Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002748-TA|BGIBMGA002748-PA|IPR002126|Cadherin
(1518 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA... 840 0.0
UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA... 820 0.0
UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D CG1... 789 0.0
UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precu... 241 1e-61
UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3; Sophophora... 238 7e-61
UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep:... 221 1e-55
UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n... 211 1e-52
UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenop... 200 2e-49
UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43; Eut... 196 3e-48
UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella ve... 195 9e-48
UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella ve... 195 9e-48
UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosop... 194 2e-47
UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep: ... 191 1e-46
UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenop... 189 4e-46
UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenop... 186 5e-45
UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome s... 179 6e-43
UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella ve... 166 5e-39
UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome sh... 165 8e-39
UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whol... 164 2e-38
UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51; Euteleosto... 161 1e-37
UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gamb... 160 3e-37
UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella ve... 159 5e-37
UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella ve... 159 7e-37
UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella ve... 159 7e-37
UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homol... 157 2e-36
UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome sh... 155 7e-36
UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella ve... 155 9e-36
UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep: C... 154 2e-35
UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella ve... 152 6e-35
UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2;... 149 6e-34
UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep:... 149 8e-34
UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42; Arthro... 148 1e-33
UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome s... 147 2e-33
UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor ... 147 2e-33
UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n... 147 2e-33
UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio "Pr... 147 2e-33
UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19; Am... 147 2e-33
UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor ... 146 4e-33
UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome sh... 146 4e-33
UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome sh... 145 7e-33
UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35; E... 145 9e-33
UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type rece... 144 1e-32
UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella ve... 144 2e-32
UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome s... 141 2e-31
UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5;... 140 2e-31
UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella ve... 140 2e-31
UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella ve... 140 2e-31
UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to Protocadhe... 140 3e-31
UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio "Pr... 140 3e-31
UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella ve... 140 4e-31
UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protei... 140 4e-31
UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA;... 139 5e-31
UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69; Eutel... 139 5e-31
UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin... 139 6e-31
UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A CG6... 138 1e-30
UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella ve... 138 1e-30
UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor; n=... 138 1e-30
UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein;... 137 3e-30
UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor ... 136 4e-30
UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenop... 136 4e-30
UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-lik... 136 4e-30
UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1... 135 1e-29
UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio "Ca... 134 1e-29
UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome sh... 134 1e-29
UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type rece... 134 2e-29
UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella ve... 133 3e-29
UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3;... 132 9e-29
UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor ... 131 2e-28
UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu rubri... 131 2e-28
UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA;... 130 2e-28
UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome sh... 130 2e-28
UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein;... 130 3e-28
UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 2... 130 3e-28
UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella ve... 130 4e-28
UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome s... 129 7e-28
UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome s... 128 1e-27
UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2;... 126 4e-27
UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome s... 126 5e-27
UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C CG3... 125 8e-27
UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n... 125 1e-26
UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|R... 125 1e-26
UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gamb... 124 1e-26
UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome s... 124 2e-26
UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumo... 124 2e-26
UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52; Eutele... 123 3e-26
UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenop... 122 6e-26
UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous... 122 1e-25
UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia ... 120 2e-25
UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-P... 120 4e-25
UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein;... 119 7e-25
UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome sh... 119 7e-25
UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia franciscana|... 119 7e-25
UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type rece... 118 9e-25
UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome sh... 118 2e-24
UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein;... 117 2e-24
UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75; Eu... 117 2e-24
UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12; Amnio... 117 2e-24
UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Dan... 117 3e-24
UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to ENSANGP000... 116 5e-24
UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadhe... 115 9e-24
UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein;... 115 9e-24
UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9; Theri... 115 1e-23
UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11; Clu... 114 2e-23
UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysi... 114 2e-23
UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabdit... 114 2e-23
UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Da... 113 3e-23
UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome s... 113 4e-23
UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Re... 113 4e-23
UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31; Eutel... 113 4e-23
UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Re... 113 4e-23
UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whol... 113 5e-23
UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio "Pr... 111 1e-22
UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3; ... 111 1e-22
UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella ve... 111 1e-22
UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella ve... 111 1e-22
UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor vari... 111 2e-22
UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52; Eutele... 111 2e-22
UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34; Eutel... 111 2e-22
UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15; ... 110 3e-22
UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|R... 109 4e-22
UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12; Clupeocephala... 109 4e-22
UniRef50_Q9UII7 Cluster: E-cadherin; n=5; Catarrhini|Rep: E-cadh... 109 4e-22
UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor (Dach... 109 6e-22
UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=... 109 6e-22
UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles gamb... 109 6e-22
UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor cons... 109 8e-22
UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Re... 109 8e-22
UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome sh... 108 1e-21
UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella ve... 108 1e-21
UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1; Oik... 108 1e-21
UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep: ... 108 1e-21
UniRef50_UPI0000F1D9C2 Cluster: PREDICTED: hypothetical protein;... 107 2e-21
UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein MGC146... 107 2e-21
UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella ve... 107 2e-21
UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|R... 107 2e-21
UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260; ... 107 2e-21
UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A CG6... 107 3e-21
UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome sh... 107 3e-21
UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Re... 106 4e-21
UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor (PC-... 106 5e-21
UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n... 106 5e-21
UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33; Eutel... 106 5e-21
UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor ... 105 7e-21
UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3; D... 105 7e-21
UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadhe... 105 7e-21
UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadhe... 105 9e-21
UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole... 105 9e-21
UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome s... 105 9e-21
UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG180... 105 9e-21
UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio reri... 105 1e-20
UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261; Euteleost... 105 1e-20
UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p - ... 104 2e-20
UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3; ... 104 2e-20
UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix met... 104 2e-20
UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n... 104 2e-20
UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-... 103 4e-20
UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16; Theri... 103 4e-20
UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep: C... 103 4e-20
UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein;... 103 5e-20
UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37; Clu... 103 5e-20
UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n... 102 7e-20
UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein;... 101 1e-19
UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadhe... 101 1e-19
UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204;... 101 1e-19
UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand ... 101 2e-19
UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28; Eutel... 100 3e-19
UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor (Vasc... 100 4e-19
UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|R... 100 4e-19
UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=11... 100 4e-19
UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor... 99 5e-19
UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17; Ther... 99 5e-19
UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49;... 100 6e-19
UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadhe... 99 8e-19
UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep:... 99 8e-19
UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor... 98 1e-18
UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor ... 98 1e-18
UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome sh... 97 3e-18
UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28; Tetrapoda|... 97 3e-18
UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadhe... 97 4e-18
UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n... 97 4e-18
UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|R... 97 4e-18
UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadhe... 96 6e-18
UniRef50_Q1KKR4 Cluster: Cadherin 5; n=5; Tetraodontidae|Rep: Ca... 96 8e-18
UniRef50_Q5DYB4 Cluster: Iron-regulated protein FrpC; n=1; Vibri... 95 1e-17
UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin ... 95 1e-17
UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 95 1e-17
UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|R... 95 1e-17
UniRef50_Q4SKV9 Cluster: Chromosome undetermined SCAF14565, whol... 95 2e-17
UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whol... 95 2e-17
UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n... 94 2e-17
UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella ve... 94 2e-17
UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella ve... 94 2e-17
UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to cadherin-r... 93 5e-17
UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio "Pa... 93 5e-17
UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome sh... 93 5e-17
UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173... 93 7e-17
UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein;... 92 9e-17
UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia... 92 9e-17
UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens "Protoca... 92 1e-16
UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12;... 92 1e-16
UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio "Ca... 91 2e-16
UniRef50_Q4T0W5 Cluster: Chromosome 1 SCAF10821, whole genome sh... 91 2e-16
UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep... 91 2e-16
UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23;... 91 2e-16
UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23; Eutel... 91 2e-16
UniRef50_P55291 Cluster: Cadherin-15 precursor; n=11; Tetrapoda|... 91 2e-16
UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome sh... 91 2e-16
UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadhe... 90 4e-16
UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor (Vasc... 90 4e-16
UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome s... 90 5e-16
UniRef50_Q4S7A7 Cluster: Chromosome 1 SCAF14716, whole genome sh... 89 7e-16
UniRef50_Q4SGA8 Cluster: Chromosome 17 SCAF14597, whole genome s... 89 1e-15
UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|R... 89 1e-15
UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13... 89 1e-15
UniRef50_Q5TAN1 Cluster: Protocadherin 8; n=14; Tetrapoda|Rep: P... 89 1e-15
UniRef50_Q32P55 Cluster: CDH23 protein; n=1; Homo sapiens|Rep: C... 89 1e-15
UniRef50_O95206 Cluster: Protocadherin-8 precursor; n=16; Tetrap... 89 1e-15
UniRef50_Q86UP0 Cluster: Cadherin-24 precursor; n=17; Euteleosto... 89 1e-15
UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadhe... 88 2e-15
UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadher... 88 2e-15
UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadhe... 87 3e-15
UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens "Protoca... 87 3e-15
UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whol... 87 3e-15
UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadheri... 87 3e-15
UniRef50_UPI0000F1F8F4 Cluster: PREDICTED: hypothetical protein;... 85 1e-14
UniRef50_Q6P3M3 Cluster: Cadherin 17, LI cadherin; n=4; Danio re... 85 1e-14
UniRef50_UPI00015B58A5 Cluster: PREDICTED: similar to GA18227-PA... 85 1e-14
UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3; ... 85 2e-14
UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01;... 85 2e-14
UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1; Taki... 84 2e-14
UniRef50_Q86T00 Cluster: Full-length cDNA clone CS0DK003YO17 of ... 84 2e-14
UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n... 84 3e-14
UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19; Euteleosto... 84 3e-14
UniRef50_UPI000155D1D0 Cluster: PREDICTED: hypothetical protein,... 83 4e-14
UniRef50_Q4SM63 Cluster: Chromosome 13 SCAF14555, whole genome s... 83 6e-14
UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep: Fc1-ca... 83 6e-14
UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadhe... 83 8e-14
UniRef50_Q68SP4 Cluster: Cadherin 5; n=3; Danio rerio|Rep: Cadhe... 83 8e-14
UniRef50_Q7YWB8 Cluster: Cadherin-like protein cad3; n=1; Aplysi... 83 8e-14
UniRef50_Q4S1I4 Cluster: Chromosome 6 SCAF14768, whole genome sh... 82 1e-13
UniRef50_UPI0000F20971 Cluster: PREDICTED: hypothetical protein,... 81 2e-13
UniRef50_UPI00015A74B2 Cluster: UPI00015A74B2 related cluster; n... 81 2e-13
UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whol... 81 2e-13
UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15; Tetrapoda|... 81 2e-13
UniRef50_UPI000155CE9C Cluster: PREDICTED: similar to reproducti... 81 2e-13
UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome s... 81 2e-13
UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep:... 81 2e-13
UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep: K... 81 3e-13
UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein;... 80 4e-13
UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1; Tak... 79 7e-13
UniRef50_Q60JK4 Cluster: Putative uncharacterized protein CBG244... 79 7e-13
UniRef50_UPI0000F20039 Cluster: PREDICTED: hypothetical protein;... 79 9e-13
UniRef50_UPI000065D984 Cluster: Homolog of Brachydanio rerio "E-... 79 9e-13
UniRef50_Q4SI11 Cluster: Chromosome 5 SCAF14581, whole genome sh... 79 9e-13
UniRef50_UPI0000E49DF5 Cluster: PREDICTED: similar to protocadhe... 79 1e-12
UniRef50_Q4T518 Cluster: Chromosome undetermined SCAF9471, whole... 79 1e-12
UniRef50_Q1LX34 Cluster: Novel cadherin domain containing protei... 79 1e-12
UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Re... 79 1e-12
UniRef50_Q6R0I8 Cluster: Cadherin-related neuronal receptor 3; n... 78 2e-12
UniRef50_Q02487 Cluster: Desmocollin-2 precursor; n=70; Mammalia... 78 2e-12
UniRef50_P55283 Cluster: Cadherin-4 precursor; n=74; cellular or... 78 2e-12
UniRef50_Q7PT49 Cluster: ENSANGP00000019477; n=1; Anopheles gamb... 78 2e-12
UniRef50_Q4T7X6 Cluster: Chromosome undetermined SCAF7949, whole... 77 3e-12
UniRef50_Q4S7A3 Cluster: Chromosome 1 SCAF14716, whole genome sh... 77 3e-12
UniRef50_P32926 Cluster: Desmoglein-3 precursor; n=18; Eukaryota... 77 3e-12
UniRef50_Q4SI27 Cluster: Chromosome 5 SCAF14581, whole genome sh... 77 5e-12
UniRef50_UPI0000E7FEE8 Cluster: PREDICTED: similar to desmocolli... 76 7e-12
UniRef50_A7S9Y2 Cluster: Predicted protein; n=1; Nematostella ve... 76 7e-12
UniRef50_P33545 Cluster: Desmocollin-2 precursor; n=7; Theria|Re... 76 7e-12
UniRef50_Q12864 Cluster: Cadherin-17 precursor; n=25; Tetrapoda|... 76 7e-12
UniRef50_Q676D4 Cluster: Cadherin; n=1; Oikopleura dioica|Rep: C... 76 9e-12
UniRef50_Q4SVQ0 Cluster: Chromosome undetermined SCAF13747, whol... 75 1e-11
UniRef50_A7T102 Cluster: Predicted protein; n=1; Nematostella ve... 75 1e-11
UniRef50_Q6V1P8 Cluster: Protocadherin protein; n=6; Catarrhini|... 75 2e-11
UniRef50_Q0E9Q8 Cluster: Protocadherin-17; n=6; Clupeocephala|Re... 74 3e-11
UniRef50_Q6R8F2 Cluster: Epithelial cadherin precursor (E-cadher... 74 3e-11
UniRef50_UPI00015A73E8 Cluster: UPI00015A73E8 related cluster; n... 74 3e-11
UniRef50_Q5W7K5 Cluster: Protocadherin-gamma; n=27; Clupeocephal... 74 3e-11
UniRef50_A6QP71 Cluster: MGC155243 protein; n=2; Bos taurus|Rep:... 74 3e-11
UniRef50_A7T9P1 Cluster: Predicted protein; n=1; Nematostella ve... 74 3e-11
UniRef50_Q02413 Cluster: Desmoglein-1 precursor; n=19; Mammalia|... 73 5e-11
UniRef50_UPI00006A195F Cluster: Cadherin-16 precursor (Kidney-sp... 73 6e-11
UniRef50_Q4SDX7 Cluster: Chromosome undetermined SCAF14628, whol... 73 6e-11
UniRef50_Q9VGW1 Cluster: Putative cadherin CG4509 precursor; n=3... 73 6e-11
UniRef50_UPI0000660666 Cluster: Homolog of Brachydanio rerio "E-... 73 8e-11
UniRef50_UPI0000D5721D Cluster: PREDICTED: similar to CG4655-PA,... 72 1e-10
UniRef50_Q4RE65 Cluster: Chromosome 2 SCAF15135, whole genome sh... 72 1e-10
UniRef50_A0NBP5 Cluster: ENSANGP00000031609; n=1; Anopheles gamb... 72 1e-10
UniRef50_UPI0000660623 Cluster: Homolog of Homo sapiens "Splice ... 71 2e-10
UniRef50_Q6T1F3 Cluster: M-cadherin; n=6; Danio rerio|Rep: M-cad... 71 2e-10
UniRef50_A7RYP6 Cluster: Predicted protein; n=1; Nematostella ve... 71 2e-10
UniRef50_A0NBP4 Cluster: ENSANGP00000031608; n=1; Anopheles gamb... 71 2e-10
UniRef50_UPI000155655F Cluster: PREDICTED: similar to hCG1685761... 71 3e-10
UniRef50_UPI0000F2080D Cluster: PREDICTED: similar to Dsg2 prote... 71 3e-10
UniRef50_Q3B7G9 Cluster: Si:busm1-71b9.3 protein; n=5; Danio rer... 71 3e-10
UniRef50_UPI00006600BE Cluster: Homolog of Homo sapiens "Desmogl... 70 4e-10
UniRef50_Q0YH47 Cluster: Cadherin; n=1; Geobacter sp. FRC-32|Rep... 70 4e-10
UniRef50_Q16Z56 Cluster: Cadherin, putative; n=1; Aedes aegypti|... 70 4e-10
UniRef50_A7S5N8 Cluster: Predicted protein; n=1; Nematostella ve... 70 4e-10
UniRef50_Q7TSF0 Cluster: Desmoglein-1 gamma precursor; n=5; Muri... 70 4e-10
UniRef50_Q9YGQ8 Cluster: Cadherin; n=3; Coelomata|Rep: Cadherin ... 70 6e-10
UniRef50_Q7PT75 Cluster: ENSANGP00000005839; n=2; Anopheles gamb... 70 6e-10
UniRef50_A6E164 Cluster: Large exoprotein; n=2; cellular organis... 69 8e-10
UniRef50_Q96AU6 Cluster: FAT3 protein; n=13; Eukaryota|Rep: FAT3... 69 8e-10
UniRef50_Q7TSF1 Cluster: Desmoglein-1 beta precursor; n=4; Theri... 69 8e-10
UniRef50_UPI0000F1F613 Cluster: PREDICTED: similar to Desmoglein... 69 1e-09
UniRef50_Q90Z37 Cluster: E-cadherin; n=19; Danio rerio|Rep: E-ca... 69 1e-09
UniRef50_Q7QEU4 Cluster: ENSANGP00000019269; n=1; Anopheles gamb... 69 1e-09
UniRef50_P55290 Cluster: Cadherin-13 precursor; n=40; Euteleosto... 69 1e-09
UniRef50_UPI0000DA24E5 Cluster: PREDICTED: similar to FAT tumor ... 68 2e-09
UniRef50_UPI00015A57B8 Cluster: UPI00015A57B8 related cluster; n... 68 2e-09
UniRef50_UPI0000E7F7D9 Cluster: PREDICTED: hypothetical protein;... 68 2e-09
UniRef50_UPI0000ECD04C Cluster: CDNA FLJ44366 fis, clone TRACH30... 68 2e-09
UniRef50_Q08BK3 Cluster: Dsc2l protein; n=5; Danio rerio|Rep: Ds... 68 2e-09
UniRef50_Q566L0 Cluster: Cdh26 protein; n=2; Xenopus tropicalis|... 67 4e-09
UniRef50_Q7UWZ8 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-09
UniRef50_Q14126 Cluster: Desmoglein-2 precursor; n=18; Theria|Re... 66 5e-09
UniRef50_UPI000155551A Cluster: PREDICTED: similar to Ksp-cadher... 66 7e-09
UniRef50_UPI0000F1D53E Cluster: PREDICTED: similar to cadherin 2... 66 7e-09
UniRef50_UPI0000DA2660 Cluster: PREDICTED: similar to FAT tumor ... 66 9e-09
UniRef50_Q5HZ99 Cluster: MGC85083 protein; n=2; Xenopus|Rep: MGC... 66 9e-09
UniRef50_Q17281 Cluster: Cadherin homolog; n=1; Botryllus schlos... 66 9e-09
UniRef50_UPI000155CFDF Cluster: PREDICTED: similar to protocadhe... 65 1e-08
UniRef50_UPI000155D19D Cluster: PREDICTED: similar to cadherin-l... 64 2e-08
UniRef50_Q4RJQ1 Cluster: Chromosome 13 SCAF15035, whole genome s... 64 2e-08
UniRef50_UPI0000F21093 Cluster: PREDICTED: similar to cadherin-l... 64 3e-08
UniRef50_UPI0000ECBA20 Cluster: Mucin and cadherin-like protein ... 64 3e-08
UniRef50_Q6AX88 Cluster: MGC81969 protein; n=1; Xenopus laevis|R... 64 3e-08
UniRef50_A3VZY4 Cluster: VCBS; n=6; Roseovarius|Rep: VCBS - Rose... 64 3e-08
UniRef50_Q9BIB5 Cluster: Calsyntenin/alcadein homolog protein 1,... 63 5e-08
UniRef50_Q172R3 Cluster: Cadherin, putative; n=1; Aedes aegypti|... 63 5e-08
UniRef50_Q86SJ6 Cluster: Desmoglein-4 precursor; n=16; Mammalia|... 63 5e-08
UniRef50_UPI000155C764 Cluster: PREDICTED: similar to protocadhe... 63 7e-08
UniRef50_Q7SZW3 Cluster: Novel protein similar to zebrafish epit... 63 7e-08
UniRef50_UPI0000E80331 Cluster: PREDICTED: similar to cadherin p... 62 9e-08
UniRef50_UPI0000E7FEEA Cluster: PREDICTED: similar to desmoglein... 62 9e-08
UniRef50_UPI0000ECCE39 Cluster: Desmoglein-1 precursor (Desmosom... 62 9e-08
UniRef50_A7SQA1 Cluster: Predicted protein; n=1; Nematostella ve... 62 9e-08
UniRef50_UPI0000E215FA Cluster: PREDICTED: similar to cadherin; ... 62 1e-07
UniRef50_A7RIY4 Cluster: Predicted protein; n=1; Nematostella ve... 62 1e-07
UniRef50_UPI000155D0E5 Cluster: PREDICTED: similar to intestinal... 62 2e-07
UniRef50_Q9NL47 Cluster: Cadherin; n=1; Ciona intestinalis|Rep: ... 62 2e-07
UniRef50_Q088L7 Cluster: Putative outer membrane adhesin like pr... 61 3e-07
UniRef50_Q4SNR2 Cluster: Chromosome 15 SCAF14542, whole genome s... 60 3e-07
UniRef50_Q86DU3 Cluster: Cadherin-like protein; n=65; Ditrysia|R... 60 5e-07
UniRef50_Q19194 Cluster: Cadherin family protein 5, isoform a; n... 60 5e-07
UniRef50_UPI0000DB741F Cluster: PREDICTED: similar to Cad96Cb CG... 60 6e-07
UniRef50_Q7Q1N1 Cluster: ENSANGP00000013153; n=1; Anopheles gamb... 60 6e-07
UniRef50_Q6ZTQ4 Cluster: Cadherin-like protein 28 precursor; n=1... 60 6e-07
UniRef50_P73089 Cluster: Fat protein; n=1; Synechocystis sp. PCC... 59 8e-07
UniRef50_A7SSY8 Cluster: Predicted protein; n=1; Nematostella ve... 59 8e-07
UniRef50_A0NB14 Cluster: ENSANGP00000025533; n=1; Anopheles gamb... 59 8e-07
UniRef50_Q8IXH8 Cluster: Cadherin-like protein 26 precursor; n=2... 59 8e-07
UniRef50_O62328 Cluster: Putative uncharacterized protein cdh-7;... 58 1e-06
UniRef50_Q61F88 Cluster: Putative uncharacterized protein CBG117... 58 2e-06
UniRef50_Q09EY8 Cluster: Cadherin-like protein; n=4; Helicoverpa... 58 2e-06
UniRef50_UPI00006A1DB7 Cluster: Cadherin-like protein 26 precurs... 57 3e-06
UniRef50_Q4SNR1 Cluster: Chromosome 15 SCAF14542, whole genome s... 57 3e-06
UniRef50_A5F7Q5 Cluster: Cadherin domain protein; n=23; Vibrio c... 57 3e-06
UniRef50_Q8I722 Cluster: FAT-like cadherin CDH-3; n=3; Bilateria... 57 3e-06
UniRef50_UPI0000660B21 Cluster: Homolog of Brachydanio rerio "E-... 57 4e-06
UniRef50_Q9VBV6 Cluster: CG13664-PA; n=5; Sophophora|Rep: CG1366... 57 4e-06
UniRef50_UPI0000D9A8A3 Cluster: PREDICTED: similar to fat tumor ... 56 6e-06
UniRef50_Q7QCW0 Cluster: ENSANGP00000016223; n=1; Anopheles gamb... 56 6e-06
UniRef50_UPI0000F2DD8E Cluster: PREDICTED: hypothetical protein;... 56 7e-06
UniRef50_UPI0000D67092 Cluster: PREDICTED: hypothetical protein;... 56 7e-06
UniRef50_Q21035 Cluster: Cadherin family protein 9; n=2; Caenorh... 56 7e-06
UniRef50_A7SV36 Cluster: Predicted protein; n=1; Nematostella ve... 56 7e-06
UniRef50_UPI0000F1DCEE Cluster: PREDICTED: similar to MGC81969 p... 55 1e-05
UniRef50_UPI000065D997 Cluster: Mucin and cadherin-like protein ... 55 2e-05
UniRef50_A7S9Y4 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-05
UniRef50_A7S4B9 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-05
UniRef50_UPI0000F1F39B Cluster: PREDICTED: similar to CDH26; n=2... 54 2e-05
UniRef50_UPI0000F21791 Cluster: PREDICTED: similar to MGC81969 p... 54 3e-05
UniRef50_Q4S7A6 Cluster: Chromosome 1 SCAF14716, whole genome sh... 54 3e-05
UniRef50_Q32PV3 Cluster: Zgc:123181; n=1; Danio rerio|Rep: Zgc:1... 54 4e-05
UniRef50_A4GJB0 Cluster: Hypothetical cadherin domain containing... 54 4e-05
UniRef50_Q7QAN5 Cluster: ENSANGP00000011927; n=1; Anopheles gamb... 54 4e-05
UniRef50_Q7YZI2 Cluster: PRCDH1; n=1; Proterospongia sp. ATCC 50... 53 5e-05
UniRef50_UPI0000F1E6B8 Cluster: PREDICTED: hypothetical protein;... 53 7e-05
UniRef50_UPI0000D5583D Cluster: PREDICTED: similar to Cadherin E... 53 7e-05
UniRef50_A0XZ16 Cluster: Polyhydroxyalkanoate synthesis represso... 53 7e-05
UniRef50_A7S9Y1 Cluster: Predicted protein; n=1; Nematostella ve... 53 7e-05
UniRef50_O75309 Cluster: Cadherin-16 precursor; n=21; Theria|Rep... 53 7e-05
UniRef50_UPI0001556456 Cluster: PREDICTED: similar to fat protei... 52 9e-05
UniRef50_Q6TM00 Cluster: Protocadherin-like protein; n=3; Tetrao... 52 9e-05
UniRef50_Q7ULP1 Cluster: Probable G-cadherin-possibly involved i... 52 9e-05
UniRef50_Q171X1 Cluster: Putative uncharacterized protein; n=1; ... 52 9e-05
UniRef50_UPI0000EBDDEA Cluster: PREDICTED: similar to Br-cadheri... 52 1e-04
UniRef50_A0IZI3 Cluster: Putative outer membrane adhesin like pr... 52 2e-04
UniRef50_UPI0000F204F9 Cluster: PREDICTED: hypothetical protein;... 51 2e-04
UniRef50_UPI0000ECAEAF Cluster: Epithelial-cadherin precursor (E... 51 2e-04
UniRef50_UPI0000F20007 Cluster: PREDICTED: hypothetical protein;... 51 3e-04
UniRef50_A6BZA6 Cluster: VCBS; n=1; Planctomyces maris DSM 8797|... 51 3e-04
UniRef50_Q7UY44 Cluster: Fat protein-possibly involved in cell-c... 50 4e-04
UniRef50_Q5BYL9 Cluster: SJCHGC04271 protein; n=1; Schistosoma j... 50 4e-04
UniRef50_UPI0001554BE0 Cluster: PREDICTED: similar to zinc finge... 50 6e-04
UniRef50_Q5C239 Cluster: SJCHGC04157 protein; n=1; Schistosoma j... 50 6e-04
UniRef50_Q4SDX5 Cluster: Chromosome undetermined SCAF14628, whol... 49 9e-04
UniRef50_Q4S5K3 Cluster: Chromosome 9 SCAF14729, whole genome sh... 49 9e-04
UniRef50_Q304D6 Cluster: Putative uncharacterized protein; n=4; ... 49 9e-04
UniRef50_A7SQA3 Cluster: Predicted protein; n=1; Nematostella ve... 49 9e-04
UniRef50_Q4SW86 Cluster: Chromosome undetermined SCAF13670, whol... 49 0.001
UniRef50_Q4SL21 Cluster: Chromosome 17 SCAF14563, whole genome s... 49 0.001
UniRef50_A7K3C4 Cluster: Autotransporter adhesin; n=6; Vibrio|Re... 48 0.002
UniRef50_Q7YZI1 Cluster: MBCDH1; n=1; Monosiga brevicollis|Rep: ... 48 0.002
UniRef50_O15202 Cluster: Cadherin; n=20; Catarrhini|Rep: Cadheri... 48 0.002
UniRef50_UPI0000DA3D77 Cluster: PREDICTED: similar to FAT tumor ... 48 0.003
UniRef50_UPI00005C16EA Cluster: PREDICTED: similar to Protocadhe... 48 0.003
UniRef50_A4A1I4 Cluster: Fat protein-possibly involved in cell-c... 48 0.003
UniRef50_UPI0000D5583E Cluster: PREDICTED: similar to CG3389-PA;... 47 0.003
UniRef50_O94985 Cluster: Calsyntenin-1 precursor; n=84; Euteleos... 47 0.003
UniRef50_Q80ZV4 Cluster: Cdh4 protein; n=4; Eutheria|Rep: Cdh4 p... 47 0.005
UniRef50_A2A3A3 Cluster: Protocadherin 15; n=10; Euarchontoglire... 47 0.005
UniRef50_UPI00015562FD Cluster: PREDICTED: hypothetical protein;... 46 0.006
UniRef50_A7S7D3 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.008
UniRef50_UPI000155CC4B Cluster: PREDICTED: similar to cadherin-8... 46 0.011
UniRef50_Q9I7K2 Cluster: CG4655-PA, isoform A; n=4; Diptera|Rep:... 46 0.011
UniRef50_UPI0000EBE0B4 Cluster: PREDICTED: hypothetical protein;... 45 0.014
UniRef50_Q0APJ1 Cluster: Cadherin precursor; n=1; Maricaulis mar... 45 0.018
UniRef50_A3VRI7 Cluster: Putative uncharacterized protein; n=1; ... 45 0.018
UniRef50_UPI00005A0191 Cluster: PREDICTED: similar to protocadhe... 44 0.024
UniRef50_Q16U55 Cluster: Putative uncharacterized protein; n=1; ... 44 0.024
UniRef50_Q89NW9 Cluster: Bll3714 protein; n=2; cellular organism... 44 0.032
UniRef50_Q0YQC9 Cluster: VCBS; n=4; root|Rep: VCBS - Chlorobium ... 44 0.032
UniRef50_A3QBF9 Cluster: Peptidase S8 and S53, subtilisin, kexin... 44 0.032
UniRef50_Q5C071 Cluster: SJCHGC07450 protein; n=1; Schistosoma j... 44 0.032
UniRef50_A7SQA0 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.032
UniRef50_Q4SYR3 Cluster: Chromosome 1 SCAF11974, whole genome sh... 44 0.043
UniRef50_Q32LQ8 Cluster: Pcdh2g6 protein; n=9; Clupeocephala|Rep... 44 0.043
UniRef50_A3U2I5 Cluster: Calcium binding hemolysin protein, puta... 43 0.056
UniRef50_Q4C8Z4 Cluster: VCBS; n=1; Crocosphaera watsonii WH 850... 43 0.075
UniRef50_Q4BY77 Cluster: Integrins alpha chain:Cadherin:Na-Ca ex... 43 0.075
UniRef50_Q1YNS7 Cluster: Cadherin domain protein; n=3; gamma pro... 42 0.13
UniRef50_Q16QB3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.13
UniRef50_Q482D1 Cluster: Glycosyl hydrolase, family 10; n=1; Col... 42 0.17
UniRef50_Q2W246 Cluster: RTX toxins and related Ca2+-binding pro... 42 0.17
UniRef50_A0YV99 Cluster: Cadherin domain protein; n=1; Lyngbya s... 42 0.17
UniRef50_A7TD52 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.23
UniRef50_Q4REY7 Cluster: Chromosome 13 SCAF15122, whole genome s... 41 0.30
UniRef50_Q05V94 Cluster: Putative uncharacterized protein; n=1; ... 41 0.30
UniRef50_Q8IM41 Cluster: Putative uncharacterized protein; n=1; ... 41 0.30
UniRef50_O14045 Cluster: tRNA 2'-phosphotransferase Tpt1; n=1; S... 41 0.30
UniRef50_UPI00006611E9 Cluster: Homolog of Brachydanio rerio "Pr... 40 0.40
UniRef50_Q0ALR4 Cluster: Serralysin precursor; n=1; Maricaulis m... 40 0.40
UniRef50_A6ANU4 Cluster: Calx-beta domain family; n=1; Vibrio ha... 40 0.40
UniRef50_A0LXF0 Cluster: Secreted protein containing cadherin do... 40 0.40
UniRef50_Q5CXK0 Cluster: CpTSP9, extracellular protein with 3 TS... 40 0.40
UniRef50_Q4S5J7 Cluster: Chromosome 9 SCAF14729, whole genome sh... 40 0.53
UniRef50_A6QNT5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.53
UniRef50_Q58EZ6 Cluster: Mucin-like protocadherin; n=4; Catarrhi... 40 0.53
UniRef50_Q9HBB8 Cluster: Mucin and cadherin-like protein precurs... 40 0.53
UniRef50_Q6GM27 Cluster: MGC84020 protein; n=8; Euteleostomi|Rep... 39 0.92
UniRef50_Q8WPL2 Cluster: Similar to protocadherin; n=1; Oikopleu... 39 0.92
UniRef50_Q2USL0 Cluster: Predicted protein; n=1; Aspergillus ory... 39 0.92
UniRef50_UPI0000DA41C0 Cluster: PREDICTED: similar to desmocolli... 39 1.2
UniRef50_UPI00004D822A Cluster: Cadherin-related tumor suppresso... 39 1.2
UniRef50_Q3AR75 Cluster: VCBS; n=1; Chlorobium chlorochromatii C... 39 1.2
UniRef50_UPI0000E80D81 Cluster: PREDICTED: hypothetical protein;... 38 1.6
UniRef50_UPI000038CC1E Cluster: COG2374: Predicted extracellular... 38 1.6
UniRef50_Q7UDU8 Cluster: Probable aggregation factor core protei... 38 1.6
UniRef50_A5UP67 Cluster: Predicted ATPase, AAA+ superfamily; n=1... 38 1.6
UniRef50_Q9V498 Cluster: Calsyntenin-1 precursor; n=4; Diptera|R... 38 1.6
UniRef50_UPI0000EBD4DB Cluster: PREDICTED: similar to cadherin 4... 38 2.1
UniRef50_Q4T6A7 Cluster: Chromosome undetermined SCAF8850, whole... 38 2.1
UniRef50_A7I315 Cluster: Putative uncharacterized protein; n=1; ... 38 2.1
UniRef50_A5BC30 Cluster: Putative uncharacterized protein; n=1; ... 38 2.1
UniRef50_A7SYG7 Cluster: Predicted protein; n=1; Nematostella ve... 38 2.1
UniRef50_A7SEI0 Cluster: Predicted protein; n=1; Nematostella ve... 38 2.1
UniRef50_A2E630 Cluster: Putative uncharacterized protein; n=1; ... 38 2.1
UniRef50_UPI0000E49142 Cluster: PREDICTED: hypothetical protein;... 38 2.8
UniRef50_A4SN36 Cluster: Transcriptional regulator, LysR family;... 38 2.8
UniRef50_A6SDK5 Cluster: Putative uncharacterized protein; n=1; ... 38 2.8
UniRef50_UPI000155324D Cluster: PREDICTED: hypothetical protein;... 37 4.9
UniRef50_A0A2I3 Cluster: Cadherin EGF LAG seven-pass G-type rece... 37 4.9
UniRef50_Q7NWV4 Cluster: Putative uncharacterized protein; n=1; ... 37 4.9
UniRef50_Q1KML3 Cluster: Polyunsaturated fatty acid synthase; n=... 37 4.9
UniRef50_Q7QL20 Cluster: ENSANGP00000014560; n=1; Anopheles gamb... 37 4.9
UniRef50_Q6KIG6 Cluster: Arginyl-tRNA synthetase; n=1; Mycoplasm... 37 4.9
UniRef50_O25028 Cluster: Flagellar P-ring protein precursor; n=5... 37 4.9
UniRef50_UPI0000E48C5A Cluster: PREDICTED: hypothetical protein,... 36 6.5
UniRef50_UPI0000498E4A Cluster: hypothetical protein 91.t00005; ... 36 6.5
UniRef50_A3IRF3 Cluster: Putative uncharacterized protein; n=1; ... 36 6.5
UniRef50_A7F2I4 Cluster: Putative uncharacterized protein; n=1; ... 36 6.5
UniRef50_UPI0000E48848 Cluster: PREDICTED: similar to Kielin; n=... 36 8.6
UniRef50_UPI00005A3590 Cluster: PREDICTED: similar to mu-protoca... 36 8.6
UniRef50_UPI0000EB1578 Cluster: Mucin and cadherin-like protein ... 36 8.6
UniRef50_Q4BYZ3 Cluster: Integrins alpha chain:Cadherin:Na-Ca ex... 36 8.6
UniRef50_Q2N8W0 Cluster: Putative uncharacterized protein; n=1; ... 36 8.6
UniRef50_Q0WIL8 Cluster: General secretion pathway protein D; n=... 36 8.6
UniRef50_A0UVP8 Cluster: Na-Ca exchanger/integrin-beta4 precurso... 36 8.6
>UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG14900-PA - Tribolium castaneum
Length = 1761
Score = 840 bits (2079), Expect = 0.0
Identities = 421/803 (52%), Positives = 553/803 (68%), Gaps = 30/803 (3%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S VN+EVTLLDANDNNP F+P+NLY F S+ K+G V+G++ A+DPDLG+NG+V Y +Q
Sbjct: 455 SAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQ 514
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ N T+ PFK++P +G +SV + + GRH LFVEASDQP NPSERR SLAVVTIEV
Sbjct: 515 KAPNNTV--PFKVDPKSGKISVNQKVVTPGRHLLFVEASDQPLNPSERRSSLAVVTIEVQ 572
Query: 561 RGT-KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
+ T KG +PDF+GAPYEFWVG NVG+GTSVGQIRV D ++ + YDLLH Y EGVP
Sbjct: 573 QQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRVADVPDRRTIIYDLLHSYHEGVP 632
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
FAVEERSG ITVVD+L YNR Y+FEAV E +++VTN T+HVVD DE+ +L+K
Sbjct: 633 FAVEERSGTITVVDNLENYNRQNYEFEAVVTNEK-EMTLVTNVTIHVVDPKDEKTILMKA 691
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+PI FHVKEN+ IG++ N N +G V F IANQ+DVT+ I+I DG+++
Sbjct: 692 GTAPIEFHVKENAGNLLIGRLGFKN-----ANSSGLV-FSIANQKDVTEHISITSDGSLY 745
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T KPLDRE RDVYR+TV+AE++KG I+G GIYQVTI+++DENDN P FEH+ YEG + EN
Sbjct: 746 TVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEHSKYEGKVTEN 805
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG-DS-LDREK 857
GTE+ ++ +I +D D G N F T+FG G E F +D NTG + F DS LDRE+
Sbjct: 806 CISGTEVDLNYLIHVSDKDTGDNGQFGVTIFGNGSEKFRLDRNTGKIFFTSADSPLDREE 865
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ--IEENSKVRIHRETKLNGTAG 915
++ L LVA+D GGL EA LIIM+ DENDN P F Q + E+ + KL G
Sbjct: 866 TGIFNLRLVAKDQGGLYDEAILIIMVEDENDNAPTFVQFIVYEDIGAEVEEYDKLGNRIG 925
Query: 916 -FTIIEVKPKNKFALDV---------DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
F +E K + L ++ PL ++ E++ +GT +IKL A D D G N
Sbjct: 926 HFEQLENSTKGTYVLTPAYTRAKKAKSKMSPLVVLKEDVGVGTPVIKLVAEDRDFGDNAV 985
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNL 1025
++YE SE YIP ++ SA+ + +YF+++ +G + V+R+LPPESEFRLNISA D G L
Sbjct: 986 VKYEMVSETYIP-NEYSAEPFHLTQYFMVHATNGEISVSRTLPPESEFRLNISASDKGGL 1044
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
D+ISVR+ ++DVNDH PVF K+WYNF+ EEA Y+R ++G+V+A D DFG NAN+TY IQ
Sbjct: 1045 KDHISVRLTIEDVNDHPPVFSKSWYNFDAEEASYSRNIIGRVEAIDGDFGPNANITYKIQ 1104
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDV 1144
D LPF I+P GVL+++G LDRET+DKY VVA+DN DV
Sbjct: 1105 EKDPKLPFAITPQGGVLTIDGVLDRETKDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDV 1164
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
NDN P FY +D+LL +PE++ SNHN++ IPVY AT+ EN+PIGT V ++FAND+
Sbjct: 1165 NDNPPSFYGYDDLL--PNPESNTYSNHNYQE--DIPVYYATVAENSPIGTPVTRIFANDS 1220
Query: 1205 DFIGNGNGLILYSLPQRKNQQNL 1227
DF GNGNGL+L+ +P +KN+QNL
Sbjct: 1221 DFTGNGNGLLLFDIPYKKNRQNL 1243
Score = 282 bits (692), Expect = 5e-74
Identities = 126/190 (66%), Positives = 163/190 (85%)
Query: 204 SGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
+G+RIHK + F IHA DQD+ + A +RY++I+GN+R +FSLD VNGSLF+E+E+D+D+
Sbjct: 261 TGERIHKLLTFDPAIHAFDQDIAIDAPIRYDIIAGNERHIFSLDHVNGSLFIEREIDIDS 320
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
E +L NTFVLQ+QASQ++NP KT ARVE+E++DLNDNLPEFEVDFYNISIVENLPNGF
Sbjct: 321 ERSLPGNTFVLQIQASQVDNPAKTGVARVEVEIMDLNDNLPEFEVDFYNISIVENLPNGF 380
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
SVLQ++A D+DQG+N EF+YQL+D GAF++D R+GWLTVR+Q+VLDRE S+LRM+VYA
Sbjct: 381 SVLQIIAVDQDQGDNAEFSYQLEDNTGAFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYA 440
Query: 384 KETNPSVVGT 393
KE PSVV +
Sbjct: 441 KEKVPSVVSS 450
Score = 209 bits (511), Expect = 4e-52
Identities = 106/204 (51%), Positives = 142/204 (69%), Gaps = 33/204 (16%)
Query: 5 RKNLNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEG 64
R NL+L+PVD++ED H FTYRD NRT VS++LA+S++ LVDSD+P+NV+KF++ CD+D+G
Sbjct: 52 RNNLSLKPVDKDEDVHYFTYRDFNRTTVSLLLARSLEDLVDSDNPRNVLKFKVSCDYDDG 111
Query: 65 DDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI 124
+D+ I++ LSVTVY+EDVND+ P+F+ PY + VDELTP G
Sbjct: 112 EDI---------ITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVG----------- 151
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
LTIF+ IRA DRDKPNTPNSDV Y+I+SGN+ G FAL+SS + L+L
Sbjct: 152 -------------LTIFRGIRASDRDKPNTPNSDVQYAIISGNERGKFALDSSQQAFLIL 198
Query: 185 RKVLDYDAGDKEFQLVIMASGKRI 208
++ LDYD GD+EF L I AS + I
Sbjct: 199 KRPLDYDTGDREFLLTIAASDRGI 222
Score = 110 bits (265), Expect = 2e-22
Identities = 171/711 (24%), Positives = 296/711 (41%), Gaps = 98/711 (13%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEV 308
+GSL+ K LD + + + L V A + T +V I + D NDN P FE
Sbjct: 741 DGSLYTVKPLDRETR-----DVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEH 795
Query: 309 DFYNISIVENLPNGFSV---LQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVR 364
Y + EN +G V + +DKD G+NG+F + + F +D +G +
Sbjct: 796 SKYEGKVTENCISGTEVDLNYLIHVSDKDTGDNGQFGVTIFGNGSEKFRLDRNTGKIFFT 855
Query: 365 N-QTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPD 423
+ + LDRE +++ AK+ G + ++ I + NAP V+ D
Sbjct: 856 SADSPLDREETGIFNLRLVAKDQG----GLYDEAILIIMVEDE--NDNAPTFVQFIVYED 909
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSM------KSNAKVGT 477
+G + E + ++ F +E + P + + + M K + VGT
Sbjct: 910 -IGAEVEEYDKLGNRIGHFEQLENSTKGTYVLTPAYTRAKKAKSKMSPLVVLKEDVGVGT 968
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLT---------ITSPFKINPNTGTVSVAESPIL 528
+ K+ A D D G N +V Y++ + + +T F ++ G +SV+ +
Sbjct: 969 PVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGEISVSRTLPP 1028
Query: 529 EGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
E L + ASD+ +++ +T + P P F + Y F
Sbjct: 1029 ESEFRLNISASDKGGLKDH-------ISVRLTIEDVNDHP--PVFSKSWYNFDAEEASYS 1079
Query: 589 GTSVGQIRVNDA-FEQN-DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE 646
+G++ D F N +++Y + + +PFA+ + GV+T+ L R + Y+F
Sbjct: 1080 RNIIGRVEAIDGDFGPNANITYK-IQEKDPKLPFAITPQGGVLTIDGVLDRETKDKYNFV 1138
Query: 647 AVALQ---ENANLSIVTNATVHVVDVNDE------RGVLLKGAHS------------PII 685
VA + +LS N V+V+DVND LL S P+
Sbjct: 1139 VVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVY 1198
Query: 686 F-HVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQK 742
+ V ENS G + +IF N S GNG G + F I +++ + I +++G + T
Sbjct: 1199 YATVAENSPIGTPVTRIF-ANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIG 1257
Query: 743 PLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTI--YIED-ENDNPPVFEHATYEGFIME 798
LD E ++++ +T++A + +S + VT+ ED ++ PVF H YE + E
Sbjct: 1258 KLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEE 1317
Query: 799 NSKIGTEIKMDNI----------------IKATDADEGTNALFMYTLFG---EGKEMFDV 839
N + ++ N+ ++A D D G N Y + G E F +
Sbjct: 1318 NVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRADEAARRFTI 1377
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDE 886
D TG V+ I + R+ +Y + A D G SS A + + + D+
Sbjct: 1378 DPITGQVRAIA-NFARDAGKVYGFDVKATDRRGADDGKSSIANVFVYVLDD 1427
Score = 85.8 bits (203), Expect = 8e-15
Identities = 122/480 (25%), Positives = 199/480 (41%), Gaps = 48/480 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VEV ++D NDN P F + Y S+ N G + ++ AVD D G N Y L+
Sbjct: 349 VEVEIMDLNDNLPEF-EVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDN-- 405
Query: 505 LTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPS--ERRYSLAVVTIEVT 560
T F ++ TG ++V + +L E R L ++ + PS + + V IEVT
Sbjct: 406 ---TGAFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGASAVNIEVT 462
Query: 561 -RGTKGNKPD-IPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEE 616
N P IP+ + Y F S++ IG VGQI D V+Y +
Sbjct: 463 LLDANDNNPTFIPNNL---YNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQKAPNN 519
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV- 675
VPF V+ +SG I+V + R + EA N + + A V ++V + G
Sbjct: 520 TVPFKVDPKSGKISVNQKVVTPGRHLLFVEASDQPLNPSERRSSLAVV-TIEVQQQTGKG 578
Query: 676 LLKG----AHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+KG +P F V N G ++GQI ++ + T L + + V
Sbjct: 579 TVKGLPDFIGAPYEFWVGGNVGVGTSVGQI---RVADVPDRRTIIYDLLHSYHEGV--PF 633
Query: 731 AIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
A+ E GTI L+ R Y + K + + VTI++ D D +
Sbjct: 634 AVEERSGTITVVDNLENYNRQNYEFEAVVTNEKEMTL---VTNVTIHVVDPKDEKTILMK 690
Query: 790 ---ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD-VDENTGV 845
A E + EN+ N++ + N+ + K++ + + +
Sbjct: 691 AGTAPIEFHVKENA--------GNLLIGRLGFKNANSSGLVFSIANQKDVTEHISITSDG 742
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEA---ELIIMIGDENDNKPEFNQIEENSKV 902
+ LDRE + +Y+L+++A + G + ++ I + DENDNKP F + KV
Sbjct: 743 SLYTVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEHSKYEGKV 802
Score = 82.6 bits (195), Expect = 8e-14
Identities = 51/131 (38%), Positives = 74/131 (56%), Gaps = 22/131 (16%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG PSLSSTA+L+VTV DVP++++ + PVF RYYE+E+EENV P+++++LN+TE Y
Sbjct: 1275 DLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEENVPVPLKVLTLNVTESY 1334
Query: 1286 E---------------------NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
N ++RY IL D RR F IDP G + + + R+
Sbjct: 1335 STTASYGHHIVRLQAKDPDLGLNGEVRYQILGRADEAARR-FTIDPITGQVRAIANFARD 1393
Query: 1325 VKDTYEVIVRA 1335
Y V+A
Sbjct: 1394 AGKVYGFDVKA 1404
Score = 74.9 bits (176), Expect = 2e-11
Identities = 119/458 (25%), Positives = 192/458 (41%), Gaps = 66/458 (14%)
Query: 166 GNDDGHFA-LESSHKPVLLLRKVLDY--DAGDKEFQLVIMASGKRIHKEILFPEPIHAID 222
GN GHF LE+S K +L A K LV++ + ++ + A D
Sbjct: 921 GNRIGHFEQLENSTKGTYVLTPAYTRAKKAKSKMSPLVVLKEDVGVGTPVI---KLVAED 977
Query: 223 QDLGVGATLRYELISG----ND--------RKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
+D G A ++YE++S N+ + F + + NG + + + L ++E
Sbjct: 978 RDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGEISVSRTLPPESE------ 1031
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
F L + AS R+ IE D+ND+ P F +YN E + + +V A
Sbjct: 1032 -FRLNISASDKGGLKDHISVRLTIE--DVNDHPPVFSKSWYNFDAEEASYSRNIIGRVEA 1088
Query: 331 TDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D D G N TY++ DPK F+I P+ G LT+ VLDRE V AK+ NP
Sbjct: 1089 IDGDFGPNANITYKIQEKDPKLPFAITPQGGVLTI--DGVLDRETKDKYNFVVVAKD-NP 1145
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
+ + + L + +E V + YD+ L N E
Sbjct: 1146 T--------------KGESLSSFVNVEVNVL----DVNDNPPSFYGYDDLL---PNPESN 1184
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL--GQNGMVLYDLQRTSNLT 506
+N N +P +Y ++ N+ +GT + ++ A D D NG++L+D+ N
Sbjct: 1185 TY-SNHNYQEDIP--VYYATVAENSPIGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNR- 1240
Query: 507 ITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT-IEVTRGT 563
+ F I+ G V+ E + H + + ASD +PS +L VVT I+V
Sbjct: 1241 -QNLFTIDSKEGIVTTIGKLDFENQNMHNITIVASDL-GSPSLSSTALLVVTVIDVPEDL 1298
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF 601
+ + P F YE V NV + V + V +++
Sbjct: 1299 Q--SMEHPVFAHRYYEVEVEENVPVPLKVLTLNVTESY 1334
Score = 72.9 bits (171), Expect = 6e-11
Identities = 59/178 (33%), Positives = 87/178 (48%), Gaps = 10/178 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN--LQANTFVLQ 275
I A+DQD G A Y+L ++ F+LDS G L + + LD E L+ + +
Sbjct: 385 IIAVDQDQGDNAEFSYQL--EDNTGAFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKE 442
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKD 334
S +++ L + +E+ LLD NDN P F + YN +L G V Q+ A D D
Sbjct: 443 KVPSVVSSKLGASAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPD 502
Query: 335 QGENGEFTYQLDD-PKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
G NG TY + P F +DP+SG ++V NQ V+ H L ++ + NPS
Sbjct: 503 LGRNGIVTYSIQKAPNNTVPFKVDPKSGKISV-NQKVVTPGRH-LLFVEASDQPLNPS 558
Score = 70.5 bits (165), Expect = 3e-10
Identities = 112/406 (27%), Positives = 175/406 (43%), Gaps = 66/406 (16%)
Query: 597 VNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEA-VALQENAN 655
V++ + N+ S + H + F V +G I+V SR P +F ++ +
Sbjct: 991 VSETYIPNEYSAEPFHLTQY---FMVHATNGEISV----SRTLPPESEFRLNISASDKGG 1043
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGA-AIGQIFHTNMSSIYGNGTG 714
L + + + DVND V K ++ F +E S IG++ + +G
Sbjct: 1044 LKDHISVRLTIEDVNDHPPVFSKSWYN---FDAEEASYSRNIIGRV--EAIDGDFGPNA- 1097
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFT-QKPLDREKRDVYRMTVIAEFN--KGVISGAGIY 771
N+ + I ++D AI G + T LDRE +D Y V+A+ N KG S +
Sbjct: 1098 NITYKI-QEKDPKLPFAITPQGGVLTIDGVLDRETKDKYNFVVVAKDNPTKGE-SLSSFV 1155
Query: 772 QVTIYIEDENDNPPVF----------EHATYEGF------------IMENSKIGTEIKMD 809
V + + D NDNPP F E TY + ENS IGT +
Sbjct: 1156 NVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVYYATVAENSPIGTPVTR- 1214
Query: 810 NIIKATDAD--EGTNALFMYTL-FGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
I A D+D N L ++ + + + ++ +F +D G+V IG LD E + M+ +++
Sbjct: 1215 --IFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIG-KLDFENQNMHNITI 1271
Query: 866 VARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
VA D G LSS A L++ + D PE Q E+ V HR + +EV+
Sbjct: 1272 VASDLGSPSLSSTALLVVTVIDV----PEDLQSMEHP-VFAHR---------YYEVEVEE 1317
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L V L G I++L A D D GLNG++RY+
Sbjct: 1318 NVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQ 1363
Score = 69.3 bits (162), Expect = 8e-10
Identities = 34/75 (45%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Query: 1440 QATDSDIGINADIRYQIL---NEQAPRFAIDPVSGTVRVVAALARDAGRVFGFXXXXXXX 1496
QA D D+G+N ++RYQIL +E A RF IDP++G VR +A ARDAG+V+GF
Sbjct: 1348 QAKDPDLGLNGEVRYQILGRADEAARRFTIDPITGQVRAIANFARDAGKVYGFDVKATDR 1407
Query: 1497 XXXXXXXXXXXNVFV 1511
NVFV
Sbjct: 1408 RGADDGKSSIANVFV 1422
Score = 66.9 bits (156), Expect = 4e-09
Identities = 85/351 (24%), Positives = 153/351 (43%), Gaps = 38/351 (10%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQ-IRVNDAFEQN----DVSYDLLHGYEEGVPFAVEER 625
P F+GAPY+ V +G ++ + IR +D + N DV Y ++ G E G FA++
Sbjct: 133 PVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNTPNSDVQYAIISGNERG-KFALDSS 191
Query: 626 SGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
++ Y+ +F +A + TN T+ + VND + K
Sbjct: 192 QQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRSTNTTIRIT-VNDNDDLSPKFTKG-- 248
Query: 685 IFHVKENSAGAAIGQIFHTNMS---SIYGNGT-----GNVRF--LIANQQDVTDDIAIAE 734
++ + N G+ H ++ +I+ +R+ + N++ + +
Sbjct: 249 VYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAPIRYDIIAGNERHIFSLDHV-- 306
Query: 735 DGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISG---AGIYQVTIYIEDENDNPPVFEHA 790
+G++F ++ +D + +R + T + + + G+ +V + I D NDN P FE
Sbjct: 307 NGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVARVEVEIMDLNDNLPEFEVD 366
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y I+EN G + I A D D+G NA F Y L + F +D TG +
Sbjct: 367 FYNISIVENLPNGFSVLQ---IIAVDQDQGDNAEFSYQL-EDNTGAFTLDSRTGWLTVRD 422
Query: 851 DS-LDREKKIMYKLSLVARD------TGGLSSEA-ELIIMIGDENDNKPEF 893
S LDREK+ ++ + A++ + L + A + + + D NDN P F
Sbjct: 423 QSVLDREKRSTLRMQVYAKEKVPSVVSSKLGASAVNIEVTLLDANDNNPTF 473
Score = 66.5 bits (155), Expect = 5e-09
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 10/188 (5%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+P G +++++ A+D D G N + Y+ L V+ V++
Sbjct: 372 IVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDNTGAFTLDSRTGWLTVRDQSVLDREKR 431
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF-KKTWYNFNVEEAQ 1058
+ + E + S L +N + V + D ND+ P F YNF
Sbjct: 432 STLRMQVYAKEKVPSVVSSKLGASAVN----IEVTLLDANDNNPTFIPNNLYNFITNSDL 487
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
V+G++ A D D G+N +TY IQ P++T +PF++ P +G +SVN ++ T ++
Sbjct: 488 KIGDVVGQIHAIDPDLGRNGIVTYSIQKAPNNT-VPFKVDPKSGKISVNQKV--VTPGRH 544
Query: 1117 ILTVVARD 1124
+L V A D
Sbjct: 545 LLFVEASD 552
Score = 66.1 bits (154), Expect = 7e-09
Identities = 133/602 (22%), Positives = 236/602 (39%), Gaps = 61/602 (10%)
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
R+V + V +++ G VT+Y+ED ND+ PVF A Y+ + E + +G I
Sbjct: 97 RNVLKFKVSCDYDDGEDIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFR 156
Query: 809 DNIIKATDADEGT--NALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
I+A+D D+ N+ Y + G + F +D + + LD
Sbjct: 157 G--IRASDRDKPNTPNSDVQYAIISGNERGKFALDSSQQAFLILKRPLDY---------- 204
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
DTG + E ++ I + P + N+ +RI + + FT K
Sbjct: 205 ---DTG----DREFLLTIAASDRGIPPRST---NTTIRITVNDNDDLSPKFT------KG 248
Query: 926 KFALDVDQLGPLFLIPENI-PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
+ +++ P+ E I + T ++A D D ++ IRY+ I ++
Sbjct: 249 VYRTRINEFYPI--TGERIHKLLTFDPAIHAFDQDIAIDAPIRYDI-----IAGNERHIF 301
Query: 985 ALEVKRYFVINERHGHVIVARSLPPES-EFRLNISALDGGNLNDNISVRVFVKDVNDHFP 1043
+L+ + ER + RSLP + ++ S +D V V + D+ND+ P
Sbjct: 302 SLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVARVEVEIMDLNDNLP 361
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F+ +YN ++ E + ++ A D D G NA +Y Q D F + TG L+
Sbjct: 362 EFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSY--QLEDNTGAFTLDSRTGWLT 419
Query: 1104 VNGE--LDRETEDKYILTVVARDN----GXXXXXXXXXXXXXXXXDVNDNSPKF-----Y 1152
V + LDRE + V A++ D NDN+P F Y
Sbjct: 420 VRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGASAVNIEVTLLDANDNNPTFIPNNLY 479
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
F + K + + + + +I++ AP T KV N
Sbjct: 480 NFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQK-APNNTVPFKVDPKSGKISVNQKV 538
Query: 1213 LI--LYSLPQRKNQQNLGLPS--LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
+ + L + Q L PS SS A++ + V + + P FI YE +
Sbjct: 539 VTPGRHLLFVEASDQPLN-PSERRSSLAVVTIEVQQQTGKGTVKGLPDFIGAPYEFWVGG 597
Query: 1269 NVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
NV + + + + + + Y +L+ + F ++ R+GT+ +V + + +
Sbjct: 598 NVGVGTSVGQIRVADVPDRRTIIYDLLHSYHEGV--PFAVEERSGTITVVDNLENYNRQN 655
Query: 1329 YE 1330
YE
Sbjct: 656 YE 657
Score = 45.6 bits (103), Expect = 0.011
Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 15/153 (9%)
Query: 231 LRYELISGNDRKLFSLDSVNGS-LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
++Y +ISGN+R F+LDS + L L++ LD D F+L + AS P ++
Sbjct: 173 VQYAIISGNERGKFALDSSQQAFLILKRPLDYDTGD----REFLLTIAASDRGIPPRSTN 228
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVM-------ATDKDQGENGEF 341
+ I + D +D P+F Y I E P G + +++ A D+D +
Sbjct: 229 TTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAPI 288
Query: 342 TYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
Y + + + FS+D +G L + + +D E
Sbjct: 289 RYDIIAGNERHIFSLDHVNGSLFIEREIDIDSE 321
Score = 44.4 bits (100), Expect = 0.024
Identities = 57/247 (23%), Positives = 102/247 (41%), Gaps = 17/247 (6%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRF- 718
+ TV+V DVND V + GA P V E G I + + +V++
Sbjct: 120 SVTVYVEDVNDHAPVFV-GA--PYQLAVDELTPVGLTIFRGIRASDRDKPNTPNSDVQYA 176
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+I+ + + ++ + ++PLD + D + IA ++G+ + + I +
Sbjct: 177 IISGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRSTNTTIRITVN 236
Query: 779 DENDNPPVFEHATY-----EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GE 832
D +D P F Y E + + +I + D I A D D +A Y + G
Sbjct: 237 DNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAPIRYDIIAGN 296
Query: 833 GKEMFDVDENTGVVKFIGD-SLDREKKI---MYKLSLVAR--DTGGLSSEAELIIMIGDE 886
+ +F +D G + + +D E+ + + L + A D + A + + I D
Sbjct: 297 ERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVARVEVEIMDL 356
Query: 887 NDNKPEF 893
NDN PEF
Sbjct: 357 NDNLPEF 363
Score = 36.3 bits (80), Expect = 6.5
Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 31/146 (21%)
Query: 1240 VTVADVPDEVEMSDKPVFISRYYELEIEE-----NVNAPVELVSLNLTEHYENFKMRYYI 1294
+T+ DV D PVF +Y + EE N+ VE + + N + Y I
Sbjct: 1052 LTIEDVNDH-----PPVFSKSWYNFDAEEASYSRNIIGRVEAID---GDFGPNANITYKI 1103
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAED 1354
+ D + F I P+ G L + DRE KD Y +V A+ P +
Sbjct: 1104 ---QEKDPKLPFAITPQGGVLTIDGVLDRETKDKYNFVVVAKDN-----------PTKGE 1149
Query: 1355 VLEGMTKYDVKVVVRIKDVNDNSPKF 1380
L V V V + DVNDN P F
Sbjct: 1150 SLSSF----VNVEVNVLDVNDNPPSF 1171
>UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG14900-PA - Nasonia vitripennis
Length = 2225
Score = 820 bits (2028), Expect = 0.0
Identities = 458/1009 (45%), Positives = 625/1009 (61%), Gaps = 71/1009 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V VEVTLLDANDNNPVFVP NL E +S+ KVGT++G+V AVD DLG NG+V Y LQ
Sbjct: 702 SSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQ 761
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
R N T PF +N +TG ++VA+SPILEGRHA+F+EA+DQPANPSERR+SLAVVTI+V
Sbjct: 762 RPGNFTGKMPFAVNSDTGVITVADSPILEGRHAIFIEAADQPANPSERRFSLAVVTIDVF 821
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
R +G+K PDF+GAPYEFWVG+NV +GTSVGQIRVN+A N+V YDLLH Y EGVPF
Sbjct: 822 R-PEGSK--APDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNGNEVVYDLLHSYHEGVPF 878
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG- 679
AVEERSG ITVVD++ RY + YDFEAV E +LS+VTN ++HVVD NDE G+ KG
Sbjct: 879 AVEERSGTITVVDEIERYKQSSYDFEAVVTNEK-SLSLVTNVSIHVVDPNDESGIFAKGT 937
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+P++FHV+EN+AGA IG + N S + NV FLIANQQDV +IAI + G ++
Sbjct: 938 TKAPLVFHVRENAAGAFIGHVVPANAS----DSLKNVHFLIANQQDVA-EIAITDTGVLY 992
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T L+REKR Y +T IAE +GV G++QV I ++DE+DN P+F + YEG I EN
Sbjct: 993 TPTGLNREKRQNYSLTAIAESPRGV----GVFQVMIIVDDEDDNAPIFSASAYEGRISEN 1048
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS---LDRE 856
S+ GTE+ M N + A D DE ++ FM+TL GEG ++F +D NTG V FIG++ LDRE
Sbjct: 1049 SQTGTEVIMTNHVSARDPDEDSS--FMFTLRGEGSDLFRIDRNTGRVFFIGNATELLDRE 1106
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ--IEENSKVRIHRETKLNGTA 914
+K +Y L +VA + SS L I + DENDN P F Q I + +R+ ++ A
Sbjct: 1107 EKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSFVQMVILPDQGIRVSKDKTDKDPA 1166
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
+ V + D PL +PEN+ IG II+L A D D G N +I Y SE+
Sbjct: 1167 PTQLTSV-------TNSDYRSPLLYVPENVTIGIPIIRLVARDPDDGKNAEITYNILSEI 1219
Query: 975 YIPPS--KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVR 1032
S + + VKRYFV++ R G + VA +LP E++ L I+A D G L DN+++R
Sbjct: 1220 GGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAETDIVLEIAARDHGGLMDNVTIR 1279
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--DTD 1090
V DVNDH PVFK++WY F+V E + R +G+ +ATDADFG NAN+TY + P+ D
Sbjct: 1280 VHAFDVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNANITYELVPTNLDNS 1339
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ FE+S G S+ G LDRET D Y V+A+D G DVNDN P+
Sbjct: 1340 VKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDGG-KIKMSSSVDIEIHVQDVNDNPPR 1398
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
FY F E+ D + + +++P+Y A++ EN+ +GT V K+ AND+DF GNG
Sbjct: 1399 FYGFQEMGRLPSNLVDVYRKDSKQ--VLVPIYYASVPENSQVGTIVTKIHANDSDFAGNG 1456
Query: 1211 NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE--------MSD--KPVFISR 1260
NG+IL+ +P + Q S+ + L+ TV ++ E + SD P S
Sbjct: 1457 NGVILFDIPHVRGQMQYF--SIDNKEGLVTTVGNLDYETQNVHNLTIVASDLGSPSLTST 1514
Query: 1261 ----YYELEIEENVNAPVELVSLNL---TEHYENFKMRYYIL------NENDTDIRRTFV 1307
L+++E + P V + E EN + IL N D IR + +
Sbjct: 1515 ALLIVRILDVDEGPDEPKRPVFQHRYYEVEVEENSPVPMRILDLNVSDNNKDEQIRYSII 1574
Query: 1308 I-----------DPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVL 1356
+ DP+NG+L+L+ SPDREV+D YE+ VR ++ K SR +P MIYPV L
Sbjct: 1575 LDEGDGREHFSLDPKNGSLFLLTSPDREVRDRYELKVRVDKVKTSRGMPVMIYPVVGKRL 1634
Query: 1357 EGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
G+ + K+++++KDVNDN+P+F RP++ +PT+A +GY V++++
Sbjct: 1635 NGLGPNEAKIILKVKDVNDNAPRFKTNGRPILAVLPTSAYYGYNVIKVE 1683
Score = 395 bits (972), Expect = e-108
Identities = 216/418 (51%), Positives = 283/418 (67%), Gaps = 33/418 (7%)
Query: 5 RKNLNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEG 64
R +L + PVD+EED+ F Y+D+N+THVSV+LAQS++ LVD+D+P+N++KFRLGCD+ +G
Sbjct: 298 RNHLTIMPVDKEEDSKYFAYKDVNKTHVSVVLAQSLEDLVDADAPRNLLKFRLGCDYSDG 357
Query: 65 DDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA-- 122
D + +S++LSVTVY+EDVND+ P F+D PYHVTVDELTPTG F + A
Sbjct: 358 SDSL--------VSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHAFD 409
Query: 123 ---PIGPSLTIPLTVPRGLTIFK-DIRAFDRD-----KP-NTPNSDVHYS-IVSGNDDGH 171
P P+ + + +G K + + R KP + D Y I+S ND G
Sbjct: 410 KDKPNTPNSDVHYAIIKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGT 469
Query: 172 FALESSHKPVLLLRKVLDYDAGDKEFQLVIMAS---------GKRIHKEILFPEPIHAID 222
+S++ + + V+D D D +F + + IHKEI F PI AID
Sbjct: 470 -PPKSTNTTITIT--VVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAID 526
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
QD + + Y++ISGN+R LF LD NG+LFL++ +DLDAE NL NTFVLQ+ ASQ++
Sbjct: 527 QDRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQID 586
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NPLK A ARVE+E+LDLNDNLPEFEVDFYNISIVENLPNGFSVLQV+A D+DQG NGEFT
Sbjct: 587 NPLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFT 646
Query: 343 YQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRI 400
Y+L+DP GAFS+DP SGWLTV++Q+VLDRE S L+MKV A E PSVV + S +
Sbjct: 647 YELNDPSGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSV 704
Score = 99.5 bits (237), Expect = 6e-19
Identities = 121/478 (25%), Positives = 198/478 (41%), Gaps = 36/478 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VEV +LD NDN P F + Y S+ N G + +V A D D G NG Y+L S
Sbjct: 596 VEVEVLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELNDPS- 653
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVE-----ASDQPANPSERRYSLAV-VTIE 558
F ++P +G ++V + +L+ F++ QP+ S +V V +
Sbjct: 654 ----GAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVT 709
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH--GY 614
+ N +P G E S+ +GT +GQ+ ND V Y L +
Sbjct: 710 LLDANDNNPVFVP---GNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQRPGNF 766
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+PFAV +GVITV D R EA N + + A V + E
Sbjct: 767 TGKMPFAVNSDTGVITVADSPILEGRHAIFIEAADQPANPSERRFSLAVVTIDVFRPEGS 826
Query: 675 VLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+P F V N G ++GQI N + NG V L+ + +
Sbjct: 827 KAPDFIGAPYEFWVGANVPVGTSVGQI-RVNEAV---NGNEVVYDLLHSYHEGVPFAVEE 882
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
GTI ++R K+ Y + K + + + V+I++ D ND +F T +
Sbjct: 883 RSGTITVVDEIERYKQSSYDFEAVVTNEKSL---SLVTNVSIHVVDPNDESGIFAKGTTK 939
Query: 794 G---FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
F + + G I +++ A +D N F+ + E+ D TGV+ +
Sbjct: 940 APLVFHVRENAAGAFI--GHVVPANASDSLKNVHFLIANQQDVAEIAITD--TGVL-YTP 994
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
L+REK+ Y L+ +A G+ +++I++ DE+DN P F+ ++ + +T
Sbjct: 995 TGLNREKRQNYSLTAIAESPRGV-GVFQVMIIVDDEDDNAPIFSASAYEGRISENSQT 1051
Score = 73.3 bits (172), Expect = 5e-11
Identities = 96/416 (23%), Positives = 170/416 (40%), Gaps = 51/416 (12%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
++ F +DS +G + + L + + VL++ A + RV D+N
Sbjct: 1236 KRYFVMDSRSGEISVAGALPAETD-------IVLEIAARDHGGLMDNVTIRVHA--FDVN 1286
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD----DPKGAFSIDP 356
D+ P F+ +Y + E F + + ATD D G+N TY+L D F +
Sbjct: 1287 DHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNANITYELVPTNLDNSVKFEVSR 1346
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEK 416
G ++ LDRE KV AK+ + + D + Q + N P
Sbjct: 1347 YQGTFSLGGN--LDRETRDLYNFKVIAKDGGKIKMSSSVDIEIHV----QDVNDNPP--- 1397
Query: 417 TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG 476
+Y Q M + + + D+ V VP +Y S+ N++VG
Sbjct: 1398 ----------------RFYGFQEMGRLPSNLVDVYRKDSKQVLVP--IYYASVPENSQVG 1439
Query: 477 TVIGKVKAVDPDLGQNG--MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--H 532
T++ K+ A D D NG ++L+D+ F I+ G V+ + E + H
Sbjct: 1440 TIVTKIHANDSDFAGNGNGVILFDIPHVRGQM--QYFSIDNKEGLVTTVGNLDYETQNVH 1497
Query: 533 ALFVEASDQPANPSERRYSLAVVTI-EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS 591
L + ASD +PS +L +V I +V G ++P P F YE V N +
Sbjct: 1498 NLTIVASDL-GSPSLTSTALLIVRILDVDEGP--DEPKRPVFQHRYYEVEVEENSPVPMR 1554
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEG-VPFAVEERSGVITVVDDLSRYNRPMYDFE 646
+ + V+D + + Y ++ +G F+++ ++G + ++ R R Y+ +
Sbjct: 1555 ILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKNGSLFLLTSPDREVRDRYELK 1610
Score = 73.3 bits (172), Expect = 5e-11
Identities = 90/369 (24%), Positives = 159/369 (43%), Gaps = 47/369 (12%)
Query: 158 DVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG-DKEFQLVIMASGKRIHKEILFPE 216
+VH + +D G +L S+ LL+ ++LD D G D+ + V + E P
Sbjct: 1495 NVHNLTIVASDLGSPSLTST---ALLIVRILDVDEGPDEPKRPVFQHRYYEVEVEENSPV 1551
Query: 217 PIHAID---QDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT 271
P+ +D D +RY +I G+ R+ FSLD NGSLFL D + +
Sbjct: 1552 PMRILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKNGSLFLLTSPDREVRDRYELKV 1611
Query: 272 FVLQVQASQ------------LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL 319
V +V+ S+ N L +A++ +++ D+NDN P F+ + I V L
Sbjct: 1612 RVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRFKTNGRPILAV--L 1669
Query: 320 PN----GFSVLQVMATDKDQGENGEFTYQL------DDPKGAFSIDPRSGWLTVRNQTVL 369
P G++V++V A D D+G NG+ YQ+ D PK F+IDP SG +
Sbjct: 1670 PTSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDSPK--FAIDPVSGQVQAAGNFAR 1727
Query: 370 DREAHSSLRMKVY----AKETNPSVVGTFA-----DSQRIAKWRRQPLETNAPLEKTTYV 420
D +K A++ S+ F + Q + ++P E +E T
Sbjct: 1728 DAGRVFGFDVKATDRAGAEDGRSSIANVFVYVLDDNKQLVMIMGKKPGEIEPEIENITSA 1787
Query: 421 FPDKVG--TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSN-LYEFSMKSNAKVGT 477
+ G + +E + E+ + ++ ++ L + N V + ++ L +++
Sbjct: 1788 LQNVTGLDVRVRKVEPHTEKNLIDISSDMYLYAVDPNLNVMIDTDTLQNVFQSKKSEIKR 1847
Query: 478 VIGKVKAVD 486
+ + K +D
Sbjct: 1848 ELERYKLLD 1856
Score = 67.3 bits (157), Expect = 3e-09
Identities = 75/267 (28%), Positives = 120/267 (44%), Gaps = 23/267 (8%)
Query: 135 PRGLTIFKDIRAFDRD-KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
PR T+F D RA D D + N P + I + D + S+ V +VLD +
Sbjct: 552 PRNGTLFLD-RAIDLDAERNLPGNTFVLQIHASQIDNPLKVASARVEV----EVLDLNDN 606
Query: 194 DKEFQLVI--MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK-LFSLDSVN 250
EF++ ++ + + + I A D+D GV YEL ND FS+D ++
Sbjct: 607 LPEFEVDFYNISIVENLPNGFSVLQVI-AYDRDQGVNGEFTYEL---NDPSGAFSVDPIS 662
Query: 251 GSLFLEKELDLDAEHN--LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-E 307
G L ++ + LD E LQ ++ Q S + ++ VE+ LLD NDN P F
Sbjct: 663 GWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVTLLDANDNNPVFVP 722
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-----KGAFSIDPRSGWLT 362
+ + + G + QV A D D G NG Y+L P K F+++ +G +T
Sbjct: 723 GNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQRPGNFTGKMPFAVNSDTGVIT 782
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPS 389
V + +L E ++ ++ + NPS
Sbjct: 783 VADSPIL--EGRHAIFIEAADQPANPS 807
Score = 65.7 bits (153), Expect = 9e-09
Identities = 34/75 (45%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 1440 QATDSDIGINADIRYQILN---EQAPRFAIDPVSGTVRVVAALARDAGRVFGFXXXXXXX 1496
+A D D G N +RYQIL + +P+FAIDPVSG V+ ARDAGRVFGF
Sbjct: 1683 EAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQVQAAGNFARDAGRVFGFDVKATDR 1742
Query: 1497 XXXXXXXXXXXNVFV 1511
NVFV
Sbjct: 1743 AGAEDGRSSIANVFV 1757
Score = 59.7 bits (138), Expect = 6e-07
Identities = 50/173 (28%), Positives = 83/173 (47%), Gaps = 16/173 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA----LEVKRYFVIN 995
I EN+P G +++++ A D D G+NG+ YE N P S D L V+ V++
Sbjct: 619 IVENLPNGFSVLQVIAYDRDQGVNGEFTYELND----PSGAFSVDPISGWLTVQDQSVLD 674
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + L E + S + N + ++ V V + D ND+ PVF V
Sbjct: 675 REQKSFLQMKVLAVEKQ----PSVVKPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVA 730
Query: 1056 EAQY-TRRVLGKVDATDADFGQNANLTYFIQ-PSD--TDLPFEISPLTGVLSV 1104
++ + +LG+V A D D G N + Y +Q P + +PF ++ TGV++V
Sbjct: 731 QSDFKVGTILGQVHAVDNDLGTNGLVRYKLQRPGNFTGKMPFAVNSDTGVITV 783
Score = 56.0 bits (129), Expect = 7e-06
Identities = 92/430 (21%), Positives = 174/430 (40%), Gaps = 35/430 (8%)
Query: 981 LSADALEVKRYFV---INERHGHVIVARSLP-------PES--EFRLNISALDGGN--LN 1026
+ D E +YF +N+ H V++A+SL P + +FRL DG + ++
Sbjct: 304 MPVDKEEDSKYFAYKDVNKTHVSVVLAQSLEDLVDADAPRNLLKFRLGCDYSDGSDSLVS 363
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK-VDATDADFGQ--NANLTYF 1083
++SV V+V+DVNDH P F Y+ V+E T + + + A D D N+++ Y
Sbjct: 364 SHLSVTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHAFDKDKPNTPNSDVHYA 423
Query: 1084 IQPSDTDLPFEI-SPLTGVLSVNGELDRETEDK-YILTVVARDNGXXXXXXXXXXXXXXX 1141
I + F + S L + LD + D+ Y+L + A D G
Sbjct: 424 IIKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRG-TPPKSTNTTITITV 482
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK--V 1199
D +D PKF E+ + E + +H + I+++ I V +
Sbjct: 483 VDNDDLDPKF--TQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQDRDIDVPVLYDII 540
Query: 1200 FANDTDF--IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
N+ + NG + + + LP +T +L + + + + ++++ V
Sbjct: 541 SGNERGLFHLDPRNGTLFLDRAIDLDAER-NLP--GNTFVLQIHASQIDNPLKVASARVE 597
Query: 1258 ISRYYELEIEENV-NAPVELVSLNLTEHYEN-FKMRYYILNENDTDIRRTFVIDPRNGTL 1315
+ L++ +N+ V+ ++++ E+ N F + I + D + F + + +
Sbjct: 598 VE---VLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELNDPSG 654
Query: 1316 YLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT-KYDVKVVVRIKDVN 1374
P + V QK ++ + V++ V+V V + D N
Sbjct: 655 AFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVTLLDAN 714
Query: 1375 DNSPKFTNGN 1384
DN+P F GN
Sbjct: 715 DNNPVFVPGN 724
Score = 51.6 bits (118), Expect = 2e-04
Identities = 87/366 (23%), Positives = 148/366 (40%), Gaps = 28/366 (7%)
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ-IRVNDAFEQN----D 605
SL + VT + P F+ APY V G ++ + I D + N D
Sbjct: 360 SLVSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHAFDKDKPNTPNSD 419
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL---SIVTNA 662
V Y ++ G E+G F++E ++ Y+ ++ + + S T
Sbjct: 420 VHYAIIKGNEQG-KFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTPPKSTNTTI 478
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI-FHTNMSSIYGNGTGNVRFL-- 719
T+ VVD +D + + IF + +I F T + +I + +V L
Sbjct: 479 TITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQDRDIDVPVLYD 538
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISG---AGIYQVTI 775
I + + +GT+F + +D + +R++ T + + + I +V +
Sbjct: 539 IISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQIDNPLKVASARVEV 598
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ D NDN P FE Y I+EN G + + A D D+G N F Y L +
Sbjct: 599 EVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ---VIAYDRDQGVNGEFTYEL-NDPSG 654
Query: 836 MFDVDENTGVVKFIGDS-LDREKKIMYKLSLVARDTG-------GLSSEAELIIMIGDEN 887
F VD +G + S LDRE+K ++ ++A + SS E+ + + D N
Sbjct: 655 AFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVTLLDAN 714
Query: 888 DNKPEF 893
DN P F
Sbjct: 715 DNNPVF 720
Score = 39.1 bits (87), Expect = 0.92
Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 22/202 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF-------NSEVYIPPSK-----LSADALE 987
+ EN P+ I+ LN D + + QIRY + P L++ E
Sbjct: 1545 VEENSPVPMRILDLNVSD--NNKDEQIRYSIILDEGDGREHFSLDPKNGSLFLLTSPDRE 1602
Query: 988 VKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
V+ + + R V +R +P + + L+G N+ + + VKDVND+ P FK
Sbjct: 1603 VRDRYELKVRVDKVKTSRGMPVMI-YPVVGKRLNGLGPNE-AKIILKVKDVNDNAPRFKT 1660
Query: 1048 TWYNFNV---EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP-FEISPLTGVL 1102
A Y V+ KV+A D D G N + Y + + D P F I P++G +
Sbjct: 1661 NGRPILAVLPTSAYYGYNVI-KVEAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQV 1719
Query: 1103 SVNGELDRETEDKYILTVVARD 1124
G R+ + V A D
Sbjct: 1720 QAAGNFARDAGRVFGFDVKATD 1741
Score = 38.7 bits (86), Expect = 1.2
Identities = 41/118 (34%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Query: 451 DANDNNPVFVPSNLYEFS-MKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITS 509
D NDN P F + + + ++A G + KV+A DPD G NG V Y Q S
Sbjct: 1650 DVNDNAPRFKTNGRPILAVLPTSAYYGYNVIKVEAEDPDEGANGQVRY--QILGGREQDS 1707
Query: 510 P-FKINPNTGTVSVAESPILE-GRHALF-VEASDQPANPSERRYSLAVVTIEVTRGTK 564
P F I+P +G V A + + GR F V+A+D+ A + R S+A V + V K
Sbjct: 1708 PKFAIDPVSGQVQAAGNFARDAGRVFGFDVKATDR-AGAEDGRSSIANVFVYVLDDNK 1764
Score = 37.5 bits (83), Expect = 2.8
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 8/129 (6%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLF 830
VT+Y+ED ND+ P F A Y + E + G I I A D D+ N+ Y +
Sbjct: 368 VTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRG--IHAFDKDKPNTPNSDVHYAII 425
Query: 831 -GEGKEMFDVDENTGVVKFIGDSLD---REKKIMYKLSLVARDTGGLSSEAELIIMIGDE 886
G + F ++ + LD +++ + +S R T S+ + I + D
Sbjct: 426 KGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTPPKSTNTTITITVVDN 485
Query: 887 NDNKPEFNQ 895
+D P+F Q
Sbjct: 486 DDLDPKFTQ 494
>UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D
CG14900-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Cad89D CG14900-PA - Apis mellifera
Length = 1730
Score = 789 bits (1952), Expect = 0.0
Identities = 463/1027 (45%), Positives = 611/1027 (59%), Gaps = 89/1027 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V+V+VTLLDANDNNP+FVP NLYE +S++KVGTV+G+V AVD DLG NGMV Y LQ
Sbjct: 443 SSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMVRYRLQ 502
Query: 501 RTSNLTI-TSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ N T T PF ++ TGT+SV+ESPILEGRHA+FVEA+DQPANPSERR SLAVVT++V
Sbjct: 503 KPGNSTARTPPFAVDEVTGTISVSESPILEGRHAIFVEAADQPANPSERRISLAVVTVDV 562
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
R + G + PDF+GAPYEFWVG+NV +GTSVGQIR+NDA + ND+ YDLLH YEEGVP
Sbjct: 563 FR-SDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVKTNDLIYDLLHSYEEGVP 621
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
FAVEERSG ITVV+++ R++R +YDFEA+ E +L ++TN ++HVVD NDERG+ +G
Sbjct: 622 FAVEERSGTITVVEEIERFDRSIYDFEAIVTDER-DLMLITNVSIHVVDPNDERGIFTRG 680
Query: 680 -AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+P++FH +EN AGA IGQI N + G+ T RF I NQQDV DI+I EDG +
Sbjct: 681 TTTAPLVFHARENMAGAYIGQILPQNGT---GSATPATRFFIVNQQDV-PDISITEDGAL 736
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+ K LDRE R Y +TVIAE +GV G++QV++ + DEND+ P F YEG I E
Sbjct: 737 YAPKGLDREARQNYSITVIAESQRGV----GVFQVSVIVLDENDHAPEFTSPLYEGRITE 792
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG---DSLDR 855
NS GT++ + I ATD DEG N F++TL GE E+F + TG+V F G +LDR
Sbjct: 793 NSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERSELFRIHPTTGLVYFEGIDDRTLDR 852
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI----EENSKVRIHRETKL- 910
E + Y ++VA+D GGL+SE+ L I + D NDN P F ++ E+ +V +T+
Sbjct: 853 EARANYSFTIVAKDNGGLTSESRLRITVTDVNDNSPVFIRMIVLPEQGVRVSNEADTEAS 912
Query: 911 ---NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
N T + + PL L+PEN IG II+L A D D G N I
Sbjct: 913 FEGNDVVADTADDTSGAGGDRAASGRRSPLLLVPENATIGAPIIRLLAEDRDEGTNAAIT 972
Query: 968 YEFNSEVYIPPSKLSADALEV--KRYFVINERHGHVIVARSLPPESEFRLNISALDGGNL 1025
Y +E + L+ +RYF ++ R G + VAR L E+ R A D G L
Sbjct: 973 YSLVNETVSGDETVVESRLDTTNRRYFHLDPRSGEISVARGLTAETNVRFLALAKDPGGL 1032
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
DNI+VR+ V DVNDH P F K+WY F+V E Y LG+V A DAD G+NAN+TY +
Sbjct: 1033 FDNITVRIHVVDVNDHPPSFDKSWYTFDVAEGTYKGYTLGRVRAVDADHGRNANVTYELT 1092
Query: 1086 PSD------TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
D FE+ P GV+ V G LDRET + L V ARDNG
Sbjct: 1093 TRDDSGVGNVSRIFEVGPGEGVIRVTGVLDRETVPVHRLLVTARDNG-VPRLSSTVEVEV 1151
Query: 1140 XXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
DVNDN P F+ +DE+ E DE + +PVY A++ EN+P+G+ V KV
Sbjct: 1152 NVLDVNDNPPVFHDYDEI------EKDENGD-------PLPVYHASVLENSPVGSRVIKV 1198
Query: 1200 FANDTDFIGNGNGLILYSL--PQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
A+DTDF GNGNGLIL+ L P + +Q + S ++ V D+ E + S + V
Sbjct: 1199 RADDTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEG---VITVVGDLDYERQRSHRLVV 1255
Query: 1258 ISRYYELEIEENVNAPVELVSLN-------LTEHYENFKMRYY--ILNEN---------- 1298
+ + A V + N TE FK RYY + EN
Sbjct: 1256 TASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEENVEVPVLVARL 1315
Query: 1299 ----DTDIR----------------RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
D+D+R + F IDPRNG+LYL DREV D YE VR +R
Sbjct: 1316 ELADDSDVRDEHVRYSIVADETKARQLFSIDPRNGSLYLTTGVDREVNDRYEAKVRVDRV 1375
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
K R +P MIYPV + L G+ + +VVVR+KDVNDN+P+F + RP++ A+PTTA +G
Sbjct: 1376 KIGRGMPVMIYPVVGERLNGLAPNEARVVVRVKDVNDNAPRFKSRGRPILAAVPTTAHYG 1435
Query: 1399 YQVMQLK 1405
Y+V++++
Sbjct: 1436 YEVVKVE 1442
Score = 352 bits (865), Expect = 5e-95
Identities = 189/408 (46%), Positives = 262/408 (64%), Gaps = 32/408 (7%)
Query: 5 RKNLNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEG 64
R ++++ PVD++EDA F Y++ N+THVS++LAQS++ LVD++ P+N++KFR+ CD+ +
Sbjct: 37 RSHISIMPVDKDEDARFFAYKETNKTHVSLMLAQSLEDLVDTEVPRNLLKFRVVCDYSDE 96
Query: 65 DDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA-- 122
+V +++LSVTVY+ED+ND+ P F+D PYHVTVDELTP G F + A
Sbjct: 97 KFIV---------TSHLSVTVYVEDINDHAPQFVDAPYHVTVDELTPVGVTIFRGIHAVD 147
Query: 123 ---PIGPSLTIPLTVPRG-------LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF 172
P P+ + + +G L R+ + N D +++V D
Sbjct: 148 GDKPNTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVIAATDRGA 207
Query: 173 ALESSHKPVLLLRKVLDYDAGDKEFQLVIMASG---------KRIHKEILFPEPIHAIDQ 223
+++ V + VLD D D +F + + I I F PI A D+
Sbjct: 208 PARTTNTTVRIT--VLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFSTPIQATDR 265
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D + A +RY++ SGN+R F LD N +L+L++ +DLDAE NL +NTF LQ+ ASQ++N
Sbjct: 266 DRDIDAPIRYDIASGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDN 325
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
PL++ ARVE+E+LDLNDNLPEFEVD YNISIVENLPNGFSVLQV+A D+DQGENG+F Y
Sbjct: 326 PLRSGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDY 385
Query: 344 QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+L DP GAFS+D RSGWLTVR+Q+VLDRE LRM+V A E PSVV
Sbjct: 386 ELVDPSGAFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVV 433
Score = 106 bits (254), Expect = 5e-21
Identities = 184/789 (23%), Positives = 314/789 (39%), Gaps = 98/789 (12%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
R+ +++ D S+ +G+L+ K LD +A N T + + Q +
Sbjct: 716 RFFIVNQQDVPDISITE-DGALYAPKGLDREARQNYSI-TVIAESQRG-------VGVFQ 766
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV---LQVMATDKDQGENGEFTYQLDDP 348
V + +LD ND+ PEF Y I EN P G V + + ATDKD+G N F + L
Sbjct: 767 VSVIVLDENDHAPEFTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGE 826
Query: 349 KG-AFSIDPRSGWLTVR--NQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRR 405
+ F I P +G + + LDREA ++ + AK+ G R+ +
Sbjct: 827 RSELFRIHPTTGLVYFEGIDDRTLDREARANYSFTIVAKDN-----GGLTSESRL-RITV 880
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
+ N+P+ V P++ G + N + V T D + S
Sbjct: 881 TDVNDNSPVFIRMIVLPEQ-GVRVSNEADTEASFEGNDVVADTADDTSGAGGDRAASGRR 939
Query: 466 E--FSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR----------TSNLTITSP--F 511
+ NA +G I ++ A D D G N + Y L S L T+ F
Sbjct: 940 SPLLLVPENATIGAPIIRLLAEDRDEGTNAAITYSLVNETVSGDETVVESRLDTTNRRYF 999
Query: 512 KINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP 571
++P +G +SVA E + F+ + P + +T+ + + P P
Sbjct: 1000 HLDPRSGEISVARGLTAE-TNVRFLALAKDPGGLFDN------ITVRIHVVDVNDHP--P 1050
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGVP-----FAVEE 624
F + Y F V G ++G++R DA +V+Y+L + GV F V
Sbjct: 1051 SFDKSWYTFDVAEGTYKGYTLGRVRAVDADHGRNANVTYELTTRDDSGVGNVSRIFEVGP 1110
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGV------LL 677
GVI V L R P++ A LS V+V+DVND V +
Sbjct: 1111 GEGVIRVTGVLDRETVPVHRLLVTARDNGVPRLSSTVEVEVNVLDVNDNPPVFHDYDEIE 1170
Query: 678 KGAH-SPI-IFH--VKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD-IA 731
K + P+ ++H V ENS G+ + ++ + + GNG G + F + + + A
Sbjct: 1171 KDENGDPLPVYHASVLENSPVGSRVIKV-RADDTDFAGNGNGLILFDLNHPGKLEKQWFA 1229
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND-------N 783
I +++G I LD E++ +R+ V A +S V + + +E+D
Sbjct: 1230 IDSKEGVITVVGDLDYERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTER 1289
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F+H YE + EN ++ + + +D + + + +++F +D
Sbjct: 1290 APTFKHRYYEVEVEENVEVPVLVARLELADDSDVRDEHVRYSIVADETKARQLFSIDPRN 1349
Query: 844 GVVKFIGDSLDREKKIMYKLSL-VARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
G + ++ +DRE Y+ + V R G + ++G+ N + N +
Sbjct: 1350 GSL-YLTTGVDREVNDRYEAKVRVDRVKIGRGMPVMIYPVVGE------RLNGLAPN-EA 1401
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGP--LFLIPENIPIGTTIIKLNALDLDS 960
R+ ++ VK N A G L +P G ++K+ A D D
Sbjct: 1402 RV-------------VVRVKDVNDNAPRFKSRGRPILAAVPTTAHYGYEVVKVEAEDPDE 1448
Query: 961 GLNGQIRYE 969
G N +IRY+
Sbjct: 1449 GANAEIRYQ 1457
Score = 89.4 bits (212), Expect = 7e-16
Identities = 171/736 (23%), Positives = 293/736 (39%), Gaps = 87/736 (11%)
Query: 217 PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
PI A D+D G+ + L G +LF + G ++ E D + +AN + +
Sbjct: 805 PITATDKDEGINQNFVFTL-HGERSELFRIHPTTGLVYFEGIDDRTLDREARAN-YSFTI 862
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A N L T+++R+ I + D+NDN P F I ++ G V T+
Sbjct: 863 VAKD-NGGL-TSESRLRITVTDVNDNSPVF------IRMIVLPEQGVRVSNEADTEASFE 914
Query: 337 ENGEFTYQLDDPKGAFSIDPRSG-----WLTVRNQTV-------LDREAHSSLRMKVYAK 384
N DD GA SG L N T+ L + +
Sbjct: 915 GNDVVADTADDTSGAGGDRAASGRRSPLLLVPENATIGAPIIRLLAEDRDEGTNAAITYS 974
Query: 385 ETNPSVVG--TFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSF 442
N +V G T +S R+ R+ + + + T + + F
Sbjct: 975 LVNETVSGDETVVES-RLDTTNRRYFHLDPRSGEISVARGLTAETNVRFLALAKDPGGLF 1033
Query: 443 VNVEVTL--LDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
N+ V + +D ND+ P F + Y F + G +G+V+AVD D G+N V Y+L
Sbjct: 1034 DNITVRIHVVDVNDHPPSF-DKSWYTFDVAEGTYKGYTLGRVRAVDADHGRNANVTYELT 1092
Query: 501 RTSNL---TITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQ--PANPSERRYS 551
+ ++ F++ P G + V + +L+ H L V A D P S
Sbjct: 1093 TRDDSGVGNVSRIFEVGPGEGVIRV--TGVLDRETVPVHRLLVTARDNGVPRLSSTVEVE 1150
Query: 552 LAVVTIEVTRGTKGNKPDI-PDFMGAP---YEFWVGSNVGIGTSVGQIRVNDA-FEQND- 605
+ V+ + + +I D G P Y V N +G+ V ++R +D F N
Sbjct: 1151 VNVLDVNDNPPVFHDYDEIEKDENGDPLPVYHASVLENSPVGSRVIKVRADDTDFAGNGN 1210
Query: 606 --VSYDLLH-GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
+ +DL H G E FA++ + GVITVV DL + + A + +S+ + A
Sbjct: 1211 GLILFDLNHPGKLEKQWFAIDSKEGVITVVGDLDYERQRSHRLVVTASDLGSPVSLTSTA 1270
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFH------VKEN-SAGAAIGQIFHTNMSSIYGNGTGN 715
V V N++ G +P H V+EN + ++ + S + +
Sbjct: 1271 AVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEENVEVPVLVARLELADDSDVRDE---H 1327
Query: 716 VRF-LIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAE---FNKGV------ 764
VR+ ++A++ +I +G+++ +DRE D Y V + +G+
Sbjct: 1328 VRYSIVADETKARQLFSIDPRNGSLYLTTGVDREVNDRYEAKVRVDRVKIGRGMPVMIYP 1387
Query: 765 ISGAGI-------YQVTIYIEDENDNPPVFEH--ATYEGFIMENSKIGTEIKMDNIIKAT 815
+ G + +V + ++D NDN P F+ + + G E+ ++A
Sbjct: 1388 VVGERLNGLAPNEARVVVRVKDVNDNAPRFKSRGRPILAAVPTTAHYGYEVVK---VEAE 1444
Query: 816 DADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----T 870
D DEG NA Y + G E F +D +G V+ + S R+ ++ + A D
Sbjct: 1445 DPDEGANAEIRYQILGREDAPRFAIDPLSGQVRSVA-SFGRDAGRVFGFDVKATDRRGAE 1503
Query: 871 GGLSSEAELIIMIGDE 886
G SS A + + + D+
Sbjct: 1504 DGRSSIANVFVYVLDD 1519
Score = 86.2 bits (204), Expect = 6e-15
Identities = 119/489 (24%), Positives = 206/489 (42%), Gaps = 34/489 (6%)
Query: 422 PDKVGTKTENIEYYDEQLMSFV-NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
P T + D L S V VEV +LD NDN P F +LY S+ N G +
Sbjct: 310 PSNTFTLQIHASQVDNPLRSGVARVEVEVLDLNDNLPEF-EVDLYNISIVENLPNGFSVL 368
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHAL---F 535
+V A D D G+NG Y+L S F ++ +G ++V + +L E R L
Sbjct: 369 QVIARDRDQGENGQFDYELVDPS-----GAFSVDARSGWLTVRDQSVLDRERRDRLRMRV 423
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM-GAPYEFWVGSNVGIGTSVGQ 594
V +P+ + R S + +++V + P F+ G YE S+ +GT +GQ
Sbjct: 424 VAVEKRPSVVAPRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQ 483
Query: 595 IR-VNDAFEQND-VSYDLL---HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA 649
+ V+D N V Y L + PFAV+E +G I+V + R EA
Sbjct: 484 VHAVDDDLGPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVSESPILEGRHAIFVEAAD 543
Query: 650 LQENANLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMS 706
N + ++ A TV V + + +P F V N G ++GQI +
Sbjct: 544 QPANPSERRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAV 603
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
T ++ + + + + A+ E GTI + ++R R +Y I + ++
Sbjct: 604 K-----TNDLIYDLLHSYEEGVPFAVEERSGTITVVEEIERFDRSIYDFEAIVTDERDLM 658
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG-TEIKMDNIIKATDADEGTNAL 824
I V+I++ D ND +F T ++ +++ + I+ T A
Sbjct: 659 L---ITNVSIHVVDPNDERGIFTRGTTTAPLVFHARENMAGAYIGQILPQNGTGSATPAT 715
Query: 825 FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
+ + +++ D+ + LDRE + Y ++++A G+ ++ +++
Sbjct: 716 RFFIV--NQQDVPDISITEDGALYAPKGLDREARQNYSITVIAESQRGV-GVFQVSVIVL 772
Query: 885 DENDNKPEF 893
DEND+ PEF
Sbjct: 773 DENDHAPEF 781
Score = 85.8 bits (203), Expect = 8e-15
Identities = 137/540 (25%), Positives = 225/540 (41%), Gaps = 75/540 (13%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F ++ RSG I+V L+ F A+A +T +HVVDVND K
Sbjct: 999 FHLDPRSGEISVARGLTAETNVR--FLALAKDPGGLFDNIT-VRIHVVDVNDHPPSFDKS 1055
Query: 680 AHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDDIAIAE-- 734
++ F V E + G +G++ + + +G NV + + + D V + I E
Sbjct: 1056 WYT---FDVAEGTYKGYTLGRV--RAVDADHGRNA-NVTYELTTRDDSGVGNVSRIFEVG 1109
Query: 735 --DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH--- 789
+G I LDRE V+R+ V A N GV + +V + + D NDNPPVF
Sbjct: 1110 PGEGVIRVTGVLDRETVPVHRLLVTARDN-GVPRLSSTVEVEVNVLDVNDNPPVFHDYDE 1168
Query: 790 ----------ATYEGFIMENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGK--- 834
Y ++ENS +G+ + ++A D D N L ++ L GK
Sbjct: 1169 IEKDENGDPLPVYHASVLENSPVGSRVIK---VRADDTDFAGNGNGLILFDLNHPGKLEK 1225
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKP 891
+ F +D GV+ +GD LD E++ ++L + A D G L+S A +I+ + +E+D +
Sbjct: 1226 QWFAIDSKEGVITVVGD-LDYERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEE 1284
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
+ K R + E ++ ++ + + DV + I + +
Sbjct: 1285 GTTERAPTFKHRYY-EVEVEENVEVPVLVARLELADDSDVRDEHVRYSIVADETKARQLF 1343
Query: 952 KLN----ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
++ +L L +G++ ++ + ++V + K+ + V Y V+ ER
Sbjct: 1344 SIDPRNGSLYLTTGVDREVNDRYEAKVRVDRVKIGR-GMPVMIYPVVGER---------- 1392
Query: 1008 PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE---EAQYTRRVL 1064
LN G + V V VKDVND+ P FK A Y V+
Sbjct: 1393 -------LN------GLAPNEARVVVRVKDVNDNAPRFKSRGRPILAAVPTTAHYGYEVV 1439
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
KV+A D D G NA + Y I + F I PL+G + R+ + V A D
Sbjct: 1440 -KVEAEDPDEGANAEIRYQILGREDAPRFAIDPLSGQVRSVASFGRDAGRVFGFDVKATD 1498
Score = 62.5 bits (145), Expect = 9e-08
Identities = 67/251 (26%), Positives = 113/251 (45%), Gaps = 34/251 (13%)
Query: 231 LRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ----------- 277
+RY +++ R+LFS+D NGSL+L +D + +A V +V+
Sbjct: 1328 VRYSIVADETKARQLFSIDPRNGSLYLTTGVDREVNDRYEAKVRVDRVKIGRGMPVMIYP 1387
Query: 278 -ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI--SIVENLPNGFSVLQVMATDKD 334
+ N L +ARV + + D+NDN P F+ I ++ G+ V++V A D D
Sbjct: 1388 VVGERLNGLAPNEARVVVRVKDVNDNAPRFKSRGRPILAAVPTTAHYGYEVVKVEAEDPD 1447
Query: 335 QGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVY------AKET 386
+G N E YQ+ + A F+IDP SG VR+ R+A V A++
Sbjct: 1448 EGANAEIRYQILGREDAPRFAIDPLSG--QVRSVASFGRDAGRVFGFDVKATDRRGAEDG 1505
Query: 387 NPSVVGTFA---DSQR--IAKWRRQPLETNAPLEKTTYVFPDKVG--TKTENIE-YYDEQ 438
S+ F D Q+ + R+P++ LE T V + G + +E + ++
Sbjct: 1506 RSSIANVFVYVLDDQKQVVMVVGRRPMDIEPQLENITAVLHNVTGFDVRVRKLEPHIEKN 1565
Query: 439 LMSFVNVEVTL 449
L+ + +V L
Sbjct: 1566 LIDTTSTDVYL 1576
Score = 62.1 bits (144), Expect = 1e-07
Identities = 50/175 (28%), Positives = 83/175 (47%), Gaps = 14/175 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA----LEVKRYFVIN 995
I EN+P G +++++ A D D G NGQ F+ E+ P S DA L V+ V++
Sbjct: 357 IVENLPNGFSVLQVIARDRDQGENGQ----FDYELVDPSGAFSVDARSGWLTVRDQSVLD 412
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF-KKTWYNFNV 1054
+ R + E + ++ +G + + ++ V V + D ND+ P+F Y
Sbjct: 413 RERRDRLRMRVVAVEKRPSV-VAPRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVA 471
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQ-PSDTDL---PFEISPLTGVLSVN 1105
VLG+V A D D G N + Y +Q P ++ PF + +TG +SV+
Sbjct: 472 RSDSKVGTVLGQVHAVDDDLGPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVS 526
Score = 61.7 bits (143), Expect = 2e-07
Identities = 83/349 (23%), Positives = 149/349 (42%), Gaps = 31/349 (8%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQ-IRVNDAFEQN----DVSYDLLHGYEEGVPFAVEER 625
P F+ APY V +G ++ + I D + N DV Y ++ G EEG F++E
Sbjct: 118 PQFVDAPYHVTVDELTPVGVTIFRGIHAVDGDKPNTPNSDVHYAIVKGNEEG-KFSLESG 176
Query: 626 SGVITVVDDLSRYNRPMYDFEAV-ALQENANLSIVTNATVH--VVDVNDERGVLLKGAHS 682
++ + Y+ +F V A + + TN TV V+D +D + +
Sbjct: 177 HRTALILREPVDYDNGDREFTLVIAATDRGAPARTTNTTVRITVLDNDDLDPKFTRDVYK 236
Query: 683 PIIFHVKENSAGAAIGQI-FHTNMSSIYGNGT--GNVRFLIANQQDVTDDIAIAEDGTIF 739
I+ +I F T + + + +R+ IA+ + ++ T++
Sbjct: 237 AKIYEFYPMPEHPIFVRINFSTPIQATDRDRDIDAPIRYDIASGNERGFFHLDPKNATLY 296
Query: 740 TQKPLDRE-KRDVYRMTVIAEFNKGVISG---AGIYQVTIYIEDENDNPPVFEHATYEGF 795
++ +D + +R++ T + + + +G+ +V + + D NDN P FE Y
Sbjct: 297 LKRAIDLDAERNLPSNTFTLQIHASQVDNPLRSGVARVEVEVLDLNDNLPEFEVDLYNIS 356
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS-LD 854
I+EN G + + A D D+G N F Y L + F VD +G + S LD
Sbjct: 357 IVENLPNGFSVLQ---VIARDRDQGENGQFDYELV-DPSGAFSVDARSGWLTVRDQSVLD 412
Query: 855 REKKIMYKLSLVA----------RDTGGLSSEAELIIMIGDENDNKPEF 893
RE++ ++ +VA R+ SS ++ + + D NDN P F
Sbjct: 413 RERRDRLRMRVVAVEKRPSVVAPRNGSSSSSSVDVDVTLLDANDNNPIF 461
Score = 58.0 bits (134), Expect = 2e-06
Identities = 105/461 (22%), Positives = 181/461 (39%), Gaps = 52/461 (11%)
Query: 911 NGTAGFTIIEVKPKN-KFALDV--DQLGPLFLIPENIPIGTTI---IKLNALDLDSGLNG 964
N T T+++ + KF DV ++ + +PE+ PI I + A D D ++
Sbjct: 213 NTTVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEH-PIFVRINFSTPIQATDRDRDIDA 271
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
IRY+ S ++ L+ K + +R + R+LP + F L I A N
Sbjct: 272 PIRYDIASG-----NERGFFHLDPKNATLYLKRAIDLDAERNLPSNT-FTLQIHASQVDN 325
Query: 1025 -LNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
L ++ V V V D+ND+ P F+ YN ++ E + +V A D D G+N Y
Sbjct: 326 PLRSGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDY 385
Query: 1083 -FIQPSDTDLPFEISPLTGVLSVNGE--LDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
+ PS F + +G L+V + LDRE D+ + VVA +
Sbjct: 386 ELVDPSGA---FSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVVAPRNGSSSS 442
Query: 1140 XXXDV-------NDNSPKFY-------------AFDELLEWKHPEADELS-NHNFESVMM 1178
DV NDN+P F +L H D+L N +
Sbjct: 443 SSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMVRYRLQ 502
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
P + + +++ + + + + + Q N PS ++
Sbjct: 503 KPGNSTARTPPFAVDEVTGTISVSESPILEGRHAIFVEAADQPAN------PSERRISLA 556
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
+VTV + S +P F+ YE + NV + + L + + + Y +L+
Sbjct: 557 VVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVKTNDLIYDLLHSY 616
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTY--EVIVRAER 1337
+ + F ++ R+GT+ +V +R + Y E IV ER
Sbjct: 617 EEGV--PFAVEERSGTITVVEEIERFDRSIYDFEAIVTDER 655
Score = 54.4 bits (125), Expect = 2e-05
Identities = 49/182 (26%), Positives = 82/182 (45%), Gaps = 16/182 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ-- 277
A D+D G YEL+ + FS+D+ +G L + + LD E + V+ V+
Sbjct: 372 ARDRDQGENGQFDYELVDPSGA--FSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKR 429
Query: 278 ---ASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDK 333
+ N ++ V++ LLD NDN P F + Y + + G + QV A D
Sbjct: 430 PSVVAPRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDD 489
Query: 334 DQGENGEFTYQLDDPKGA------FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
D G NG Y+L P + F++D +G ++V +L E ++ ++ + N
Sbjct: 490 DLGPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVSESPIL--EGRHAIFVEAADQPAN 547
Query: 388 PS 389
PS
Sbjct: 548 PS 549
Score = 46.0 bits (104), Expect = 0.008
Identities = 85/376 (22%), Positives = 146/376 (38%), Gaps = 26/376 (6%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE-AQYTRRVLGKVDATDADFGQ--NANLT 1081
+ ++SV V+V+D+NDH P F Y+ V+E + + A D D N+++
Sbjct: 100 VTSHLSVTVYVEDINDHAPQFVDAPYHVTVDELTPVGVTIFRGIHAVDGDKPNTPNSDVH 159
Query: 1082 YFIQPSDTDLPFEI-SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y I + + F + S L + +D + D+ V+A +
Sbjct: 160 YAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVIAATDRGAPARTTNTTVRIT 219
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHN-FESVMMIPVYKATIEE---NAPIGTTV 1196
D +D PKF ++ + K E + H F + +AT + +API +
Sbjct: 220 VLDNDDLDPKFTR--DVYKAKIYEFYPMPEHPIFVRINFSTPIQATDRDRDIDAPIRYDI 277
Query: 1197 AKVFANDTDFIG-NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKP 1255
A N+ F + LY LP S+T L + + V + +
Sbjct: 278 AS--GNERGFFHLDPKNATLYLKRAIDLDAERNLP--SNTFTLQIHASQVDNPLRSGVAR 333
Query: 1256 VFISRYYELEIEENV-NAPVELVSLNLTEHYEN-FKMRYYILNENDTDIRRTF---VIDP 1310
V + L++ +N+ V+L ++++ E+ N F + I + D F ++DP
Sbjct: 334 VEVE---VLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDYELVDP 390
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRAERQKY-SRELPHMIYPVAEDVLEG-MTKYDVKVVV 1368
RS V+D V+ R R + R + P G + V V V
Sbjct: 391 SGAFSVDARSGWLTVRD-QSVLDRERRDRLRMRVVAVEKRPSVVAPRNGSSSSSSVDVDV 449
Query: 1369 RIKDVNDNSPKFTNGN 1384
+ D NDN+P F GN
Sbjct: 450 TLLDANDNNPIFVPGN 465
Score = 43.6 bits (98), Expect = 0.043
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 8/152 (5%)
Query: 218 IHAIDQDLGVGATLRYELIS-GNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+HA+D DLG +RY L GN F++D V G++ + + L+ H +
Sbjct: 484 VHAVDDDLGPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVSESPILEGRHAIFVE--A 541
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNL-PEFEVDFYNISIVENLPNGFSVLQVMATD 332
A+ + A V++ D ++L P+F Y + N+P G SV Q+ D
Sbjct: 542 ADQPANPSERRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLND 601
Query: 333 KDQGENGEFTYQLDDPKGA-FSIDPRSGWLTV 363
+ + + +G F+++ RSG +TV
Sbjct: 602 AVKTNDLIYDLLHSYEEGVPFAVEERSGTITV 633
Score = 42.3 bits (95), Expect = 0.099
Identities = 54/246 (21%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-L 719
+ TV+V D+ND + + + + G I + H +V + +
Sbjct: 105 SVTVYVEDINDHAPQFVDAPYHVTVDEL--TPVGVTIFRGIHAVDGDKPNTPNSDVHYAI 162
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ ++ + + ++P+D + D VIA ++G + V I + D
Sbjct: 163 VKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVIAATDRGAPARTTNTTVRITVLD 222
Query: 780 ENDNPP-----VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEG 833
+D P V++ YE + M I I I+ATD D +A Y + G
Sbjct: 223 NDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFSTPIQATDRDRDIDAPIRYDIASGNE 282
Query: 834 KEMFDVD-ENTGVVKFIGDSLDREKKI---MYKLSLVAR--DTGGLSSEAELIIMIGDEN 887
+ F +D +N + LD E+ + + L + A D S A + + + D N
Sbjct: 283 RGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDNPLRSGVARVEVEVLDLN 342
Query: 888 DNKPEF 893
DN PEF
Sbjct: 343 DNLPEF 348
Score = 39.1 bits (87), Expect = 0.92
Identities = 35/160 (21%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
R++ + V+ +++ VT+Y+ED ND+ P F A Y + E + +G I
Sbjct: 82 RNLLKFRVVCDYSDEKFIVTSHLSVTVYVEDINDHAPQFVDAPYHVTVDELTPVGVTIFR 141
Query: 809 DNIIKATDADEGT--NALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREK-KIMYKLS 864
I A D D+ N+ Y + G + F ++ + + +D + + L
Sbjct: 142 G--IHAVDGDKPNTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLV 199
Query: 865 LVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ A D G ++ + I + D +D P+F + +K+
Sbjct: 200 IAATDRGAPARTTNTTVRITVLDNDDLDPKFTRDVYKAKI 239
Score = 38.3 bits (85), Expect = 1.6
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 28/185 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE--------LEIEENVNAPVELVSL 1279
G P+ ++ + +TV D D + V+ ++ YE + + N + P++
Sbjct: 206 GAPARTTNTTVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFSTPIQATD- 264
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ + +RY I + N+ R F +DP+N TLYL R+ D + AER
Sbjct: 265 --RDRDIDAPIRYDIASGNE---RGFFHLDPKNATLYLKRAIDLD----------AERNL 309
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGY 1399
S I+ A V + +V V + D+NDN P+F + +I P G+
Sbjct: 310 PSNTFTLQIH--ASQVDNPLRSGVARVEVEVLDLNDNLPEFEVDLYNI--SIVENLPNGF 365
Query: 1400 QVMQL 1404
V+Q+
Sbjct: 366 SVLQV 370
>UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precursor;
n=6; Coelomata|Rep: Cadherin-related tumor suppressor
precursor - Drosophila melanogaster (Fruit fly)
Length = 5147
Score = 241 bits (590), Expect = 1e-61
Identities = 212/707 (29%), Positives = 321/707 (45%), Gaps = 67/707 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D DLG A L Y ++S +FSL+ G L L LD + + ++L VQ
Sbjct: 1944 IVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYE-----EVQHYILIVQ 1998
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V +LDLNDN P F+ Y+ + EN+P V+ V A D D G
Sbjct: 1999 AQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGN 2058
Query: 338 NG--EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
NG E++ D F ID T+R + LDRE S+ + V A++ FA
Sbjct: 2059 NGLIEYSITAGDVDSEFGIDSNG---TIRTRRNLDREHRSTYTLTVTARD----CADEFA 2111
Query: 396 DSQRIAKWRRQPLETNAPLEKTTYVFPDKV-GTKTENIEYYDEQ-LMSFVNVEVTLLDAN 453
+ ET L+ Y P K T+ E + + +Q L S V V + + D N
Sbjct: 2112 SFSELE-------ETQLKLK---YRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVN 2161
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITS---- 509
D PVF+ +N E ++ N + TV+ VKAVD D G+NG + Y ++ + +
Sbjct: 2162 DEVPVFISAN--ETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPL 2219
Query: 510 PFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
PF +NP G + V ++ L + L + A D+ P L + ++
Sbjct: 2220 PFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILD-------EN 2272
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEER 625
+ P F Y V N IG V Q+ D E + Y ++ G ++ F++ E
Sbjct: 2273 DNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLG-DQNHDFSISED 2331
Query: 626 SGVITVVDDLSRYNRPMYDF----EAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+GV+ V +L+ Y E AL+ A T++++D+ND R L
Sbjct: 2332 TGVVRVAKNLNYERLSRYSLTVRAEDCALENPA--GDTAELTINILDINDNRPTFL---D 2386
Query: 682 SPIIFHVKENSAGAAIGQIFHTN-MSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIF 739
SP + V EN+ G + N + VR+ + ++ +D I A G I
Sbjct: 2387 SPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFL--KEGDSDLFRINASSGDIA 2444
Query: 740 TQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
KPLDRE++ Y +T++A + ++G GI V + ++D NDN PVFE +Y + E
Sbjct: 2445 LLKPLDREQQSEYTLTLVAMDTGSPPLTGTGI--VRVEVQDINDNDPVFELQSYHATVRE 2502
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
N GT + +ATD DEG NA + L GE F +D TG + +LDRE+
Sbjct: 2503 NLPSGTHVLTP---RATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEIS-TATTLDREET 2558
Query: 859 IMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+Y L+L+A+D T +S L I + D NDN P+F+ N V
Sbjct: 2559 SVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605
Score = 188 bits (458), Expect = 1e-45
Identities = 223/848 (26%), Positives = 355/848 (41%), Gaps = 84/848 (9%)
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ VT K + P P F+ P+ + V ++ IG ++ +R +D V++ L+ G++
Sbjct: 1809 VRVTVLDKNDSP--PQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHDG 1866
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F +E +G + + D L R + Y+ + + + + AT+ V D ND +
Sbjct: 1867 --KFLLEPSTGKLILNDTLDRETKSKYELR-IRVSDGVQYT-EAYATIQVSDTNDNPPLF 1922
Query: 677 LKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-- 733
+S F + EN+ G +GQI + G N + D +D+
Sbjct: 1923 EDTVYS---FDIPENAQRGYQVGQIVARDAD--LGQ---NAQLSYGVVSDWANDVFSLNP 1974
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G + LD E+ Y + V A+ N G S + V + D NDN P+F+ +Y
Sbjct: 1975 QTGMLTLTARLDYEEVQHYILIVQAQDN-GQPSLSTTITVYCNVLDLNDNAPIFDPMSYS 2033
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDS 852
+ EN I TE+ + A D D G N L Y++ G+ F +D N G ++ +
Sbjct: 2034 SEVFENVPIATEVVT---VSAKDIDSGNNGLIEYSITAGDVDSEFGIDSN-GTIR-TRRN 2088
Query: 853 LDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
LDRE + Y L++ ARD +S +EL P Q + ++ +L+
Sbjct: 2089 LDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLS 2148
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
T TI+ +K N + V I EN+ I T +I + A+D D G NG I Y
Sbjct: 2149 STVKVTIL-IKDVND-EVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMK 2206
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNI 1029
+D L F +N G + V +L E S + LNI+A D G +
Sbjct: 2207 EAR--DEDMGQSDPLP----FSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQST 2260
Query: 1030 SVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
++ ++ D ND+ PVF Y+ +V E ++ +V ATD D G N + Y I
Sbjct: 2261 ESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLG 2320
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
D + F IS TGV+ V L+ E +Y LTV A D D+NDN
Sbjct: 2321 DQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDN 2380
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF-ANDTDF 1206
P F D + E N + V+ + Y A + P+ + V D+D
Sbjct: 2381 RPTF--LDSPYLARVMENTVPPNGGY--VLTVNAYDA---DTPPLNSQVRYFLKEGDSDL 2433
Query: 1207 --IGNGNGLILYSLPQRKNQQ----------NLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
I +G I P + QQ + G P L+ T I+ V V D+ D +
Sbjct: 2434 FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDIND-----ND 2488
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRN 1312
PVF + Y + EN+ + +++ T+ E N K+R+ +L E+ F ID
Sbjct: 2489 PVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEH----MHRFHIDSET 2544
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
G + + DRE Y + + A+ + P A V + + + D
Sbjct: 2545 GEISTATTLDREETSVYHLTLMAQDSSITE-------PRAS---------SVNLTISVSD 2588
Query: 1373 VNDNSPKF 1380
VNDN PKF
Sbjct: 2589 VNDNIPKF 2596
Score = 165 bits (401), Expect = 8e-39
Identities = 264/1003 (26%), Positives = 408/1003 (40%), Gaps = 136/1003 (13%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V V+V + D NDN P F+ + Y ++ A GT I V D D G NG V Y
Sbjct: 1257 RLQDKVKVKVIVTDVNDNAPEFLRAP-YHVTISEGASEGTHITHVFTQDADEGLNGDVYY 1315
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPA-NPSERRYSLAV 554
L + + F ++ TG +S+ E + H L V A D +P S+ +
Sbjct: 1316 SLAKGNE---AGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITI 1372
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
V ++ + P+F + E V GT + + R +DA + + V + +
Sbjct: 1373 VVLD-------ENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISA 1425
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVND 671
G F ++ +G + + L + Y A +LS V VVD ND
Sbjct: 1426 GNRRDT-FHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDND 1484
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDD- 729
+ A I+ +KE G + T + +G G V + I+ Q+
Sbjct: 1485 NPPIFPSTA---IVRQIKE---GIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQG 1538
Query: 730 --IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ---VTIYIEDENDN 783
I E G I T + +DRE D +R+TV+A ++ S + VT+ +ED NDN
Sbjct: 1539 RHFGINTETGVIHTLREIDRESIDTFRLTVVAT-DRAQPSERQLSTEKLVTVIVEDINDN 1597
Query: 784 PPVFE--HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
PVF +A SK + M + A DAD +N L Y + +E+F +
Sbjct: 1598 APVFVSMNAAILPPKFSTSKGSSTAVMQ--VHAKDADSSSNGLVTYEIVSGPQELFKLQR 1655
Query: 842 NTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENS 900
NTG++ F G +E + Y+L+L + D + SE +S
Sbjct: 1656 NTGIITFTPGPQFKQE--VRYQLTLKSTDEA-VQSE--------------------RRSS 1692
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
+V I T +G + ++ + + ++K + G ++ EN PIGT+I+ + A L S
Sbjct: 1693 EVYITIITPGSGGSESSVPQFEQRSKLS------GSVY---ENEPIGTSILTVTA-HLAS 1742
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL-----PPESEFRL 1015
+I Y F + V S+ D R F I+ + G + A L P E E +
Sbjct: 1743 A---EIEY-FVTNVTATGSRGQVD-----RLFDIDAKLGILSTAAELDREAGPEEYEVEV 1793
Query: 1016 NISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
AL G VRV V D ND P F T + +NV E + + A D D
Sbjct: 1794 YAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPD-- 1851
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
++T+ + D F + P TG L +N LDRET+ KY L + D
Sbjct: 1852 TLGSVTFLLMDGH-DGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDG----VQYTEA 1906
Query: 1136 XXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTT 1195
D NDN P F D + + PE + ++ V I A + +NA +
Sbjct: 1907 YATIQVSDTNDNPPLFE--DTVYSFDIPEN---AQRGYQ-VGQIVARDADLGQNAQLSYG 1960
Query: 1196 VAKVFANDTDFIGNGNGLILYS--LPQRKNQ--------QNLGLPSLSSTAILMVTVADV 1245
V +AND + G++ + L + Q Q+ G PSLS+T + V D+
Sbjct: 1961 VVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDL 2020
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE-HYENFKMRYYILNENDTDIRR 1304
D + P+F Y E+ ENV E+V+++ + N + Y + D D
Sbjct: 2021 ND-----NAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVD--S 2073
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRA--------------ERQ-KYSRELPHMIY 1349
F ID NGT+ R+ DRE + TY + V A E Q K P
Sbjct: 2074 EFGID-SNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQ 2132
Query: 1350 PVAEDVL----EGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
++ L + VKV + IKDVND P F + N +
Sbjct: 2133 QTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAI 2175
Score = 151 bits (367), Expect = 1e-34
Identities = 212/854 (24%), Positives = 348/854 (40%), Gaps = 96/854 (11%)
Query: 83 VTVYIEDVNDNVPIF-LDTPYHVTVD--ELTPTGEKAFIFLI--------APIGPSLTIP 131
V + I D+NDN P+F LD T+ E G++ ++ + + I SLT
Sbjct: 928 VNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNN 987
Query: 132 LTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+ + R P S +H +++ D G L S +L+ V D+
Sbjct: 988 PNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMA-TDAGSPPLSSKLSLSVLIADVNDHT 1046
Query: 192 -AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
D + +++ + A D DLG + YE+I GN ++F + +
Sbjct: 1047 PVFDHTSYETSLPETTKVNTRFF---ALAATDIDLGDNGRISYEIIEGNTERMFGVFP-D 1102
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G LF+ LD + + + + L V P +++ V I ++D NDN P+F
Sbjct: 1103 GYLFVRAPLDRE-----ERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNST 1157
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
+ SI EN P V ++ A D+D G N E ++ L F+ID R+G+ ++ D
Sbjct: 1158 FTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGF--IKTLRPFD 1215
Query: 371 REAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTE 430
REA + A + S+ G+ A + + LE + DKV K
Sbjct: 1216 REALVKVSRNAEASGEDGSLRGSMAGNYML-------LEATVS-DNGIPRLQDKVKVK-- 1265
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
V + D NDN P F+ + Y ++ A GT I V D D G
Sbjct: 1266 ----------------VIVTDVNDNAPEFLRAP-YHVTISEGASEGTHITHVFTQDADEG 1308
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQP-ANPSE 547
NG V Y L + + F ++ TG +S+ E + H L V A D +P
Sbjct: 1309 LNGDVYYSLAKGNE---AGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLS 1365
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
S+ +V ++ + P+F + E V GT + + R +DA + +
Sbjct: 1366 SNASITIVVLD-------ENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQ 1418
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATV 664
V + + G F ++ +G + + L + Y A +LS V
Sbjct: 1419 VVFSISAGNRRDT-FHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNV 1477
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQ 723
VVD ND + A I+ +KE G + T + +G G V + I+ Q
Sbjct: 1478 LVVDDNDNPPIFPSTA---IVRQIKE---GIPLKTPIVTVTADDPDSGLNGKVSYAISKQ 1531
Query: 724 QDVTDD---IAI-AEDGTIFTQKPLDREKRDVYRMTVI----AEFNKGVISGAGIYQVTI 775
+ I E G I T + +DRE D +R+TV+ A+ ++ +S + VT+
Sbjct: 1532 EPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKL--VTV 1589
Query: 776 YIEDENDNPPVF--EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+ED NDN PVF +A SK + M + A DAD +N L Y +
Sbjct: 1590 IVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQ--VHAKDADSSSNGLVTYEIVSGP 1647
Query: 834 KEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDEND 888
+E+F + NTG++ F G +E + Y+L+L + D + SSE + I+
Sbjct: 1648 QELFKLQRNTGIITFTPGPQFKQE--VRYQLTLKSTDEAVQSERRSSEVYITIITPGSGG 1705
Query: 889 NKPEFNQIEENSKV 902
++ Q E+ SK+
Sbjct: 1706 SESSVPQFEQRSKL 1719
Score = 148 bits (359), Expect = 1e-33
Identities = 248/1102 (22%), Positives = 435/1102 (39%), Gaps = 133/1102 (12%)
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRA 146
+ DVND+ P+F + Y + EL PTG +F+ I + V + +++
Sbjct: 484 VNDVNDHEPVFEKSEYSAVLSELAPTG--SFVASITATDEDTGVNAQVHYDILSGNELKW 541
Query: 147 FDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLLR--KVLDYDAGDKEFQLVI 201
F D + I + A + P KV+ D D+ Q
Sbjct: 542 FSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQ 601
Query: 202 MASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDRKL---FSLDSVNGSLF 254
+ ++ P+ I A+ D D G ++ + L +R F+LD++ G L
Sbjct: 602 REQNVTLGEDAP-PQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLT 660
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFY-- 311
+ LD + + + + + V A P ++A A V + + D+NDN P+F Y
Sbjct: 661 TRRPLDRE-----KMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIY 715
Query: 312 -------NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-PKGAFSIDPRSGWLTV 363
+I + + + +L V A+DKD G+N Y+L+ +G F +D RSG +++
Sbjct: 716 SLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAISL 775
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPD 423
R ++ V A++ A + + K + + LE
Sbjct: 776 RGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQ---------AQ 826
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN---PVFVPSNLYEFSMKSNAKVGTVIG 480
G + + +E +++Q S N EV ++ N + ++ + N ++ T G
Sbjct: 827 AGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSG 886
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD 540
++ P D + +N +T + ++ + S A S + G+ + + D
Sbjct: 887 RITTARP---------LDREEQANYRLTI---LASSSSSSSAAASSVSYGQCIVNIAIID 934
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
N + ++L + ++P I P VG + + ++R DA
Sbjct: 935 --LNDNAPVFAL----------DRESEPTI----SLPENAAVGQEI----YLSRVRDRDA 974
Query: 601 FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIV 659
+ +SY L + + F + +GV+ + + + E +A + LS
Sbjct: 975 GVNSRISYSLTNNPNQ--QFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSK 1032
Query: 660 TNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI----FHTNMSSIYGNGTGN 715
+ +V + DVND H+P+ H ++ ++ F + I G
Sbjct: 1033 LSLSVLIADVND---------HTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGR 1083
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+ + I + + + DG +F + PLDRE+RD Y +TV + G S + + V I
Sbjct: 1084 ISYEII-EGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCR-DAGQPSRSSVVPVVI 1141
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
++ DENDN P F ++T+ I EN+ T + + A D D G NA +TL + ++
Sbjct: 1142 HVIDENDNAPQFTNSTFTFSIPENAPADTFV---GKLTAVDRDIGRNAELSFTLSSQTQD 1198
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN- 894
F +D G +K + DRE + K+S A +G S + G N
Sbjct: 1199 -FTIDTRNGFIKTL-RPFDRE--ALVKVSRNAEASGEDGS------LRGSMAGNYMLLEA 1248
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
+ +N R+ + K+ + V N A + + I E GT I +
Sbjct: 1249 TVSDNGIPRLQDKVKVK-------VIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVF 1301
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE-- 1012
D D GLNG + Y A E + F ++ G + + R L ES+
Sbjct: 1302 TQDADEGLNGDVYYSL------------AKGNEAGQ-FNLDSATGQLSLGRRLDRESQEI 1348
Query: 1013 FRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
L + A D L+ N S+ + V D ND+ P F ++ +V E T L + A
Sbjct: 1349 HHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRA 1408
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
+DAD G N+ + + I + F I +TG L ++ LD E Y L + A D G
Sbjct: 1409 SDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPS 1468
Query: 1130 XXXXXXXXXXXXXDVNDNSPKF 1151
D NDN P F
Sbjct: 1469 LSTTVLYNVLVVDD-NDNPPIF 1489
Score = 132 bits (318), Expect = 9e-29
Identities = 140/491 (28%), Positives = 224/491 (45%), Gaps = 42/491 (8%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG--TVIGKVKAVD 486
T+ + + QL + V V + D NDN PVFV N K + G T + +V A D
Sbjct: 1571 TDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKD 1630
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPAN 544
D NG+V Y++ FK+ NTG ++ P E R+ L ++++D+ A
Sbjct: 1631 ADSSSNGLVTYEIVSGPQ----ELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDE-AV 1685
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDF-MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
SERR S +TI +T G+ G++ +P F + V N IGTS+ + V
Sbjct: 1686 QSERRSSEVYITI-ITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSI--LTVTAHLAS 1742
Query: 604 NDVSYDLLHGYEEGVP------FAVEERSGVITVVDDLSRYNRP-MYDFE--AVALQENA 654
++ Y + + G F ++ + G+++ +L R P Y+ E A+AL
Sbjct: 1743 AEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQP 1802
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
S T V V+D ND L +P +++V E+ IG T + + + G
Sbjct: 1803 RTS-RTKVRVTVLDKNDSPPQFL---DTPFVYNVSED---LQIGHTIST-LRAHDPDTLG 1854
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+V FL+ + D + G + LDRE + Y + + + GV Y T
Sbjct: 1855 SVTFLLMDGHD-GKFLLEPSTGKLILNDTLDRETKSKYELRI--RVSDGV-QYTEAY-AT 1909
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-G 833
I + D NDNPP+FE Y I EN++ G ++ I A DAD G NA Y + +
Sbjct: 1910 IQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQ---IVARDADLGQNAQLSYGVVSDWA 1966
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
++F ++ TG++ LD E+ Y L + A+D G LS+ + + D NDN P
Sbjct: 1967 NDVFSLNPQTGMLTLTA-RLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAP 2025
Query: 892 EFNQIEENSKV 902
F+ + +S+V
Sbjct: 2026 IFDPMSYSSEV 2036
Score = 128 bits (310), Expect = 9e-28
Identities = 128/450 (28%), Positives = 199/450 (44%), Gaps = 34/450 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +LD NDN+PVF P Y S+ NA +G ++ +V A D D G NG + Y +
Sbjct: 2266 IRILDENDNSPVFDPKQ-YSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQ-- 2322
Query: 507 ITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPA-NPSERRYSLAVVTIEVTRGT 563
F I+ +TG V VA++ E R++L V A D NP+ L + +++
Sbjct: 2323 -NHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDIN--- 2378
Query: 564 KGNKPDIPD--FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N+P D ++ E V N G +V + + V Y L G + F
Sbjct: 2379 -DNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSD--LFR 2435
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT-VHVVDVNDERGVL-LKG 679
+ SG I ++ L R + Y VA+ + T V V D+ND V L+
Sbjct: 2436 INASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQS 2495
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDGTI 738
H+ V+EN G T ++ G +RF + + I +E G I
Sbjct: 2496 YHAT----VRENLPS---GTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHID-SETGEI 2547
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LDRE+ VY +T++A+ + A +TI + D NDN P F+ TY + E
Sbjct: 2548 STATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPE 2607
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
G + +A D D+G NA+ YT+ G + FD++ TGVV + + K
Sbjct: 2608 RISKGEFVFG---ARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKS 2664
Query: 859 ---IMYKLSLVARDTG--GLSSEAELIIMI 883
+ Y + + A D G LSS+AEL +++
Sbjct: 2665 HDDLTYTIVISAMDQGEQSLSSKAELTVIL 2694
Score = 120 bits (288), Expect = 4e-25
Identities = 130/474 (27%), Positives = 201/474 (42%), Gaps = 40/474 (8%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
++ V VT+LD NDN P+F S+ Y S+ A GT + V A D DLG N + Y L
Sbjct: 253 YLQVNVTILDVNDNPPIFDHSD-YNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAE 311
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPA--------NPSERRYSLA 553
T + F +NP TG +S E + + AS + + S R+
Sbjct: 312 TEH-----QFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRT 366
Query: 554 VVTIEVTRGTKGNKPDIPD--FMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYD 609
VT+ + T + P I F V N GT V + V D+ S
Sbjct: 367 YVTVNLL-DTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVR 425
Query: 610 LLHGYEEGVPFAVEERSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHV 666
++ G E G F +EE + ++ V L R Y+ VA+ + T + + V
Sbjct: 426 IVSGNELG-HFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDV 484
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
DVND V K +S ++ + G+ + I T+ + V + I + ++
Sbjct: 485 NDVNDHEPVFEKSEYSAVLSELAPT--GSFVASITATDEDT---GVNAQVHYDILSGNEL 539
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G I T PLDRE RD +++ A + G Q+ + I DEND P
Sbjct: 540 KWFSMDPLTGLIVTTGPLDREIRDTVELSISAR-DGGPNPKFAYTQLKVIILDENDEAPQ 598
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM----FDVDEN 842
F + E++ T + + + ATD D+GTN + L + + F +D
Sbjct: 599 FSQREQNVTLGEDAPPQTIVAL---MTATDHDQGTNGSVTFALAPSVERLYPLQFALDAL 655
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEF 893
TG + LDREK Y++S++ARD G S+ A + + + D NDN P+F
Sbjct: 656 TGQLT-TRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQF 708
Score = 117 bits (282), Expect = 2e-24
Identities = 128/469 (27%), Positives = 206/469 (43%), Gaps = 41/469 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E S VN+ +++ D NDN P F S Y ++ G + +A+D D G+N +V
Sbjct: 2574 EPRASSVNLTISVSDVNDNIPKF-DSTTYNVAVPERISKGEFVFGARALDLDDGENAVVH 2632
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVA-ESPILEGRH-----ALFVEASDQPANPSERRY 550
Y + F IN TG VS E H + + A DQ +
Sbjct: 2633 YTISGRDQ----HYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKA 2688
Query: 551 SLAVVTIEVTRGTKGNKPDI-PDFMG-APYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDV 606
L V+ P++ P F A F + +V G + ++ + +
Sbjct: 2689 ELTVIL---------RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKI 2739
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP-MYDFEAVALQ-ENANLSIVTNATV 664
Y + G G V+ SG+++V D Y +Y+ A + +L VT T+
Sbjct: 2740 RYAIAGGIM-GDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITL 2798
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
+V D ND V+ + ++ + ++E S I + ++ S GNV + + N
Sbjct: 2799 NVTDANDNAPVMEQLIYNAEV--LEEESPPQLIAVVKASDRDS---GDNGNVIYRLQNDF 2853
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
D T +I E G I+T+ LDRE+ Y V A ++GV G V +++ D+NDNP
Sbjct: 2854 DGTFEIT--ESGEIYTRMRLDREEIGDYAFVVEA-VDQGVPHMTGTASVLLHLLDKNDNP 2910
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P F + + EN++IG+ + + ++D D G NA Y+ E F ++ +G
Sbjct: 2911 PKFTR-LFSLNVTENAEIGSFVIR---VTSSDLDLGANANASYSFSENPGEKFRIEPQSG 2966
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+ G LDRE++ Y L +VA D G +E + I I D+NDN PEF
Sbjct: 2967 NITVAG-HLDREQQDEYILKVVASD-GAWRAETPITITIQDQNDNAPEF 3013
Score = 108 bits (260), Expect = 1e-21
Identities = 122/458 (26%), Positives = 184/458 (40%), Gaps = 25/458 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + L D NDN PVF Y + N VGT + + A D D +N ++ Y
Sbjct: 3314 LSSVAMLTIILTDVNDNPPVFNHKE-YHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYA 3372
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ F +N + GT+S A S E R ++ + NP S A + +
Sbjct: 3373 FLPSG--PDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAK--NPDSSMESYANLYVH 3428
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS-YDLLHGYEEG 617
V G P F+ + F V +GT VG ++ D D Y LL G
Sbjct: 3429 VL----GVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSND 3484
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F ++ +G+I V L R + +A + T+ ++ + D
Sbjct: 3485 KGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPE 3544
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDDIAI-AED 735
H ++ S A +G T + T N +F + ++ I +
Sbjct: 3545 FIKH----YYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQT 3600
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T LDRE+ Y + VI + G+ G V I +ED NDN P F G+
Sbjct: 3601 GEISTASRLDREETSTYNL-VIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGY 3659
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLF-GEGKEMFDVDENTGVVKFIGDSL 853
I EN GT I + A+D D N F Y L G+ K VD N+GVV+ S
Sbjct: 3660 ISENEPAGTSIM---TLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRST-TSF 3715
Query: 854 DREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDN 889
DRE + + + D+G +++ L I + D+NDN
Sbjct: 3716 DREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN 3753
Score = 105 bits (252), Expect = 9e-21
Identities = 219/968 (22%), Positives = 376/968 (38%), Gaps = 119/968 (12%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P F F+M + + G +I KV A P G G + Y + + + +++PN
Sbjct: 2701 PTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAI---AGGIMGDSLRVDPN 2757
Query: 517 TGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
+G +SV + + L + +++EA+D PS R S+ ++T+ VT N P +
Sbjct: 2758 SGLLSVGQDGLDYELTHLYEIWIEAADGDT-PSLR--SVTLITLNVT-DANDNAPVMEQL 2813
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
+ Y V + ++ +D + + +V Y L + ++ F + E SG I
Sbjct: 2814 I---YNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDG--TFEITE-SGEIYT 2867
Query: 632 VDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
L R Y F A+ + +++ + +H++D ND + +V E
Sbjct: 2868 RMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTR----LFSLNVTE 2923
Query: 691 NSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKR 749
N A IG + S + N + + I + G I LDRE++
Sbjct: 2924 N---AEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIE-PQSGNITVAGHLDREQQ 2979
Query: 750 DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
D Y + V+A + +TI I+D+NDN P FEH+ Y E + I +
Sbjct: 2980 DEYILKVVASDG----AWRAETPITITIQDQNDNAPEFEHSFYSFSFPE---LQQSIALV 3032
Query: 810 NIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
I ATD D +G N++ Y+L + MF +D TG + +K + +K S R
Sbjct: 3033 GQIIATDRDKQGPNSVISYSL-QQPSPMFSIDPATG-------EVFSKKAVRFKHSQYVR 3084
Query: 869 DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFA 928
+ + L ++ D N K ++ E +N I++
Sbjct: 3085 SPENMYA---LTVLATD-------------NGKPPLYSECLVN----INIVDAHNNPPKF 3124
Query: 929 LDVDQLGPLFLIPENIPIGTTIIKLNALDL-DSGLNGQIRYEFNSEVYIPPSKLSADALE 987
+ L PL P++ G I++++A D D G N ++ Y S
Sbjct: 3125 EQAEYLAPL---PQDAVRGQRIVRVHANDKQDLGTN-EMDY-------------SLMTFN 3167
Query: 988 VKRYFVINERHGHVIVARSL--PPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFP 1043
+ F + G + + + + PP + + L + A D G +D V + V N P
Sbjct: 3168 LSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTP 3227
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F Y V E + + V ATD D G N L Y I + F + TG +
Sbjct: 3228 RFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIV 3287
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
+ +LD + +Y L + +D G DVNDN P F + P
Sbjct: 3288 IQQQLDYDLIQEYHLNITVQDLG-YHPLSSVAMLTIILTDVNDNPPVFN--HKEYHCYIP 3344
Query: 1164 EADELSNHNFES-VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK 1222
E + F++ K I A + + + F G + + + +R+
Sbjct: 3345 ENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERR 3404
Query: 1223 ---NQQNLGLP--SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
Q P S+ S A L V V V + +PVF ++++ V V V
Sbjct: 3405 IYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVF---HFDVSETSAVGTRVGAV 3461
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ E+ ++ YY+L + D + F ID G +Y+ R DRE ++ V++
Sbjct: 3462 QATDKDSGEDGRV-YYLLVGSSND--KGFRIDTNTGLIYVARHLDRETQN--RVVLTVMA 3516
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPF 1397
+ Y + G + +V++ I+D ND P+F + I AP
Sbjct: 3517 KNYGS-------------IRGNDTDEAQVIISIQDGND-PPEFI--KHYYTSTISEAAPV 3560
Query: 1398 GYQVMQLK 1405
G +V +K
Sbjct: 3561 GTKVTTVK 3568
Score = 103 bits (248), Expect = 3e-20
Identities = 122/461 (26%), Positives = 194/461 (42%), Gaps = 39/461 (8%)
Query: 445 VEVTLLDANDNNPV----FVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
V V LLD ND++P+ F P ++ NA GTV+ V D D G NG +
Sbjct: 368 VTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIV 427
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVT 556
+ L F++ V + +L+ G++ L V A DQ P+ R + A +
Sbjct: 428 SGNEL---GHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQ-GTPA--RTTTAHLI 481
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
I+V P F + Y + G+ V I D V YD+L G
Sbjct: 482 IDVNDVNDHE----PVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGN 537
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-TNATVHVVDVNDER 673
E F+++ +G+I L R R + A N T V ++D NDE
Sbjct: 538 ELKW-FSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEA 596
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAI 732
+ + + E++ I + ++ + GT G+V F +A + +
Sbjct: 597 PQFSQREQNVTL---GEDAPPQTIVALM---TATDHDQGTNGSVTFALAPSVERLYPLQF 650
Query: 733 AED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
A D G + T++PLDREK Y ++VIA + V + + D NDN P F
Sbjct: 651 ALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYP 710
Query: 790 ATYEGFIMENS---KIGTEIKMDNI---IKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
Y + ++ K+ E++ + I + A+D D+G NAL Y L G+ +F +D +
Sbjct: 711 RHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARS 770
Query: 844 GVVKFIGDS-LDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
G + GD+ K YKL + ARD G S+ + I+ I
Sbjct: 771 GAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEI 811
Score = 103 bits (247), Expect = 4e-20
Identities = 121/469 (25%), Positives = 200/469 (42%), Gaps = 44/469 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL-GQNGMVLYDLQRTS 503
+ +T+ D NDN P F S Y FS + ++G++ A D D G N ++ Y LQ+ S
Sbjct: 2999 ITITIQDQNDNAPEFEHS-FYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPS 3057
Query: 504 NLTITSPFKINPNTGTV-----------SVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ F I+P TG V SP E +AL V A+D P YS
Sbjct: 3058 PM-----FSIDPATGEVFSKKAVRFKHSQYVRSP--ENMYALTVLATDNGKPPL---YSE 3107
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
+V I + N P P F A Y + + G + ++ ND + N++ Y L
Sbjct: 3108 CLVNINIVDAH--NNP--PKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSL 3163
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
+ + F+V G IT+V + P +E V + + ++ T V+ V
Sbjct: 3164 MTFNLSSI-FSVGRHDGWITLVKPIQV--PPNTRYELVVRATDRGVPPQSDETRVVIVVT 3220
Query: 671 DERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
E + + + V EN G+ I + T+ + G +R+ I+ + D
Sbjct: 3221 GENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDT---GPNGMLRYSISGGNERQDF 3277
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G I Q+ LD + Y + + + + G + + +TI + D NDNPPVF H
Sbjct: 3278 SVDERTGGIVIQQQLDYDLIQEYHLNITVQ-DLGYHPLSSVAMLTIILTDVNDNPPVFNH 3336
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF--GEGKEMFDVDENTGVVK 847
Y +I EN +GT + + A D D NA+ Y G + F ++++ G +
Sbjct: 3337 KEYHCYIPENKPVGTFVFQAH---AADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTIS 3393
Query: 848 FIGDSLDREKKIMYKLSLVARD-TGGLSSEAELIIMIGDENDNKPEFNQ 895
S D E++ +Y L + A++ + S A L + + N+ P+F Q
Sbjct: 3394 -SAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQ 3441
Score = 103 bits (246), Expect = 5e-20
Identities = 126/487 (25%), Positives = 210/487 (43%), Gaps = 51/487 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ V + +LD NDN+P F P S +A GT + A D D+G+NG+ D
Sbjct: 140 IEVRIKVLDVNDNSPEF-PEPSIAISFSESATSGTRLLLDAATDADVGENGVT--DQYEI 196
Query: 503 SNLTITSPFKI----NPN--TGTVSVAESPILE----GRHALFVEASDQPANPSERRYSL 552
+ + F++ NP+ T + + + L+ G + L + A D + P +
Sbjct: 197 VAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQV 256
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDL 610
V ++V + P P F + Y + GT V + ND + + ++Y L
Sbjct: 257 NVTILDVN-----DNP--PIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYL 309
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMY-DFEAVALQENANLSIV---------- 659
+ F V +GVI+ + R N P + ++ A Q++ ++
Sbjct: 310 AETEHQ---FTVNPETGVISTTE---RVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQD 363
Query: 660 --TNATVHVVDVNDERGVLLKG--AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
T TV+++D ND ++ + V EN+ + S NG +
Sbjct: 364 GRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTS 423
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
VR + N+ A+ + LDRE+ Y +TV+A ++G + + I
Sbjct: 424 VRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVA-MDQGTPARTTTAHLII 482
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGK 834
+ D ND+ PVFE + Y + E + G+ + I ATD D G NA Y + G
Sbjct: 483 DVNDVNDHEPVFEKSEYSAVLSELAPTGSFVAS---ITATDEDTGVNAQVHYDILSGNEL 539
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPE 892
+ F +D TG++ G LDRE + +LS+ ARD G A +L ++I DEND P+
Sbjct: 540 KWFSMDPLTGLIVTTGP-LDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQ 598
Query: 893 FNQIEEN 899
F+Q E+N
Sbjct: 599 FSQREQN 605
Score = 102 bits (244), Expect = 9e-20
Identities = 126/462 (27%), Positives = 206/462 (44%), Gaps = 39/462 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP-DLGQNGMVLYDLQRTS 503
V + ++DA++N P F + Y + +A G I +V A D DLG N M Y L T
Sbjct: 3110 VNINIVDAHNNPPKFEQAE-YLAPLPQDAVRGQRIVRVHANDKQDLGTNEMD-YSLM-TF 3166
Query: 504 NLTITSPFKINPNTGTVSVAESPIL---EGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
NL+ S F + + G +++ + PI R+ L V A+D+ P + +V VT
Sbjct: 3167 NLS--SIFSVGRHDGWITLVK-PIQVPPNTRYELVVRATDRGVPPQSDETRVVIV---VT 3220
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI-RVNDAFEQNDVSYDLLHGYEEGVP 619
G D P F Y+ V N +G+++ + +D N + + G E
Sbjct: 3221 ----GENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQD 3276
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
F+V+ER+G I + L Y + LS V T+ + DVND V
Sbjct: 3277 FSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVF-- 3334
Query: 679 GAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
H ++ EN G + Q + S N + FL + D I +GT
Sbjct: 3335 -NHKEYHCYIPENKPVGTFVFQAHAADKDSPK-NAIIHYAFLPSGP-DRHFFIMNQSNGT 3391
Query: 738 IFTQKPLDREKRDVYRMTVIAEF-NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I + D E+R +Y + + A+ + + S A +Y +++ N+ P F + +
Sbjct: 3392 ISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLY---VHVLGVNEFYPQFLQPVFHFDV 3448
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDR 855
E S +GT + ++ATD D G + Y L G + F +D NTG++ ++ LDR
Sbjct: 3449 SETSAVGTRV---GAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLI-YVARHLDR 3504
Query: 856 EKKIMYKLSLVARDTGGL----SSEAELIIMIGDENDNKPEF 893
E + L+++A++ G + + EA++II I D ND PEF
Sbjct: 3505 ETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEF 3545
Score = 99.5 bits (237), Expect = 6e-19
Identities = 120/467 (25%), Positives = 202/467 (43%), Gaps = 39/467 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V + LLD NDN P F + L+ ++ NA++G+ + +V + D DLG N Y
Sbjct: 2898 SVLLHLLDKNDNPPKF--TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENP 2955
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
F+I P +G ++VA E + + L V ASD + R + +TI+
Sbjct: 2956 G----EKFRIEPQSGNITVAGHLDREQQDEYILKVVASDG----AWRAETPITITIQ--- 3004
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-F 620
+ P+F + Y F VGQI D +Q S + + ++ P F
Sbjct: 3005 ---DQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSV-ISYSLQQPSPMF 3060
Query: 621 AVEERSGVI----TVVDDLSRYNRPMYDFEAVAL--QENANLSIVTNATVHVVDVNDERG 674
+++ +G + V S+Y R + A+ + +N + + V++ ++ D
Sbjct: 3061 SIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNI-NIVDAHN 3119
Query: 675 VLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + + + +++ G I ++ H N G + + N +
Sbjct: 3120 NPPKFEQAEYLAPLPQDAVRGQRIVRV-HANDKQDLGTNEMDYSLMTFNLSSIFS--VGR 3176
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
DG I KP+ Y + V A ++GV + +V I + EN + P F +Y+
Sbjct: 3177 HDGWITLVKPIQVPPNTRYELVVRAT-DRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQ 3235
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDS 852
+ EN +G+ I + ATD D G N + Y++ G + F VDE TG + I
Sbjct: 3236 VIVPENEPVGSTILT---VGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGI-VIQQQ 3291
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
LD + Y L++ +D G LSS A L I++ D NDN P FN E
Sbjct: 3292 LDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKE 3338
Score = 93.5 bits (222), Expect = 4e-17
Identities = 73/259 (28%), Positives = 116/259 (44%), Gaps = 22/259 (8%)
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
V + + T T II+V N ++ ++ E P G+ + + A D D+G
Sbjct: 465 VAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTG 524
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISA 1019
+N Q+ Y+ LS + L ++F ++ G ++ L E L+ISA
Sbjct: 525 VNAQVHYDI----------LSGNEL---KWFSMDPLTGLIVTTGPLDREIRDTVELSISA 571
Query: 1020 LDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
DGG N + ++V + D ND P F + N + E + ++ + ATD D G
Sbjct: 572 RDGGP-NPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGT 630
Query: 1077 NANLTYFIQPSDT---DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
N ++T+ + PS L F + LTG L+ LDRE +Y ++V+ARD G
Sbjct: 631 NGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSA 690
Query: 1134 XXXXXXXXXDVNDNSPKFY 1152
DVNDN P+FY
Sbjct: 691 TATVWLNVADVNDNDPQFY 709
Score = 91.5 bits (217), Expect = 2e-16
Identities = 81/282 (28%), Positives = 125/282 (44%), Gaps = 42/282 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN P+GT + + +A D DS N I Y F PS D + +F++N+ +G
Sbjct: 3343 IPENKPVGTFVFQAHAADKDSPKNAIIHYAFL------PS--GPD----RHFFIMNQSNG 3390
Query: 1000 HVIVARSLPPESE--FRLNISALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ A S E + L I A + ++ ++ V V VN+ +P F + ++F+V E
Sbjct: 3391 TISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSE 3450
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+G V ATD D G++ + Y + S D F I TG++ V LDRET+++
Sbjct: 3451 TSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRV 3510
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
+LTV+A++ G ++ P+F KH
Sbjct: 3511 VLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFI--------KH-------------- 3548
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
Y +TI E AP+GT V V A D D + N YS+
Sbjct: 3549 ----YYTSTISEAAPVGTKVTTVKAIDKD-VRTQNNQFSYSI 3585
Score = 90.6 bits (215), Expect = 3e-16
Identities = 94/347 (27%), Positives = 152/347 (43%), Gaps = 34/347 (9%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI- 124
+L+ AG +S+ LS++V I DVND+ P+F T Y ++ E T + F I
Sbjct: 1018 ELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDID 1077
Query: 125 -GPSLTIPLTVPRGLT-----IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
G + I + G T +F D F R + D + VS D G SS
Sbjct: 1078 LGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQ-PSRSSV 1136
Query: 179 KPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
PV++ V+D + +F S F + A+D+D+G A L + L S
Sbjct: 1137 VPVVI--HVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSS 1194
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDA----EHNLQA-------------NTFVLQVQASQ 280
+ F++D+ NG + + D +A N +A N +L+ S
Sbjct: 1195 --QTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSD 1252
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
P + +V++ + D+NDN PEF Y+++I E G + V D D+G NG+
Sbjct: 1253 NGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGD 1312
Query: 341 FTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y L + G F++D +G L++ + LDRE+ + V AK+
Sbjct: 1313 VYYSLAKGNEAGQFNLDSATGQLSLGRR--LDRESQEIHHLIVVAKD 1357
Score = 86.2 bits (204), Expect = 6e-15
Identities = 117/482 (24%), Positives = 192/482 (39%), Gaps = 61/482 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++PEN P+G+TI+ + A D D+G NG +RY + ++ F ++ER
Sbjct: 3237 IVPENEPVGSTILTVGATDDDTGPNGMLRYSISGG-------------NERQDFSVDERT 3283
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G +++ + L + E+ LNI+ D G L+ + + + DVND+ PVF Y+ +
Sbjct: 3284 GGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYI 3343
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSVNGELDRETE 1113
E + + + A D D +NA + Y PS D F I + G +S D E
Sbjct: 3344 PENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEER 3403
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y L + A++ VN+ P+F L H + E S
Sbjct: 3404 RIYTLQIKAKN--PDSSMESYANLYVHVLGVNEFYPQF-----LQPVFHFDVSETSAVGT 3456
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNLGLPSL 1232
+ K + E+ V +ND F I GLI + + QN + ++
Sbjct: 3457 RVGAVQATDKDSGEDGRVYYLLVGS--SNDKGFRIDTNTGLIYVARHLDRETQNRVVLTV 3514
Query: 1233 SSTAILMVTVADVPDEVEM-------SDKPVFISRYYELEIEENVNAPVELVSLNLTE-- 1283
+ + D DE ++ +D P FI YY I E ++ ++ +
Sbjct: 3515 MAKNYGSIRGNDT-DEAQVIISIQDGNDPPEFIKHYYTSTISEAAPVGTKVTTVKAIDKD 3573
Query: 1284 -HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
+N + Y I+N N ++++F ID + G + DRE TY +++ A
Sbjct: 3574 VRTQNNQFSYSIINGN---LKQSFKIDVQTGEISTASRLDREETSTYNLVIGA----IDT 3626
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVM 1402
LP V + ++DVNDN P FT L I P G +M
Sbjct: 3627 GLPPQ-------------TGSATVHIELEDVNDNGPTFT--PEGLNGYISENEPAGTSIM 3671
Query: 1403 QL 1404
L
Sbjct: 3672 TL 3673
Score = 83.0 bits (196), Expect = 6e-14
Identities = 66/219 (30%), Positives = 98/219 (44%), Gaps = 12/219 (5%)
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
G + + EN GT + + D DSGLNG+ S + ++L LE I
Sbjct: 391 GKVATVDENAVNGTVVAAVAVKDSDSGLNGR-----TSVRIVSGNELGHFRLEEAADLHI 445
Query: 995 NERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF--VKDVNDHFPVFKKTWYNF 1052
+G V+ + ++ L + A+D G + + V DVNDH PVF+K+ Y+
Sbjct: 446 VRVNG-VLDREEI---GKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSA 501
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E T + + ATD D G NA + Y I + F + PLTG++ G LDRE
Sbjct: 502 VLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREI 561
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D L++ ARD G D ND +P+F
Sbjct: 562 RDTVELSISARDGG-PNPKFAYTQLKVIILDENDEAPQF 599
Score = 80.2 bits (189), Expect = 4e-13
Identities = 50/147 (34%), Positives = 80/147 (54%), Gaps = 10/147 (6%)
Query: 220 AIDQDLGV-GATLRYELISGN-DRKLFSLDSVNGS-----LFLEKELDLDAEHNLQANTF 272
A D D+G G T +YE+++GN D K + + N S L LE +LD E ++
Sbjct: 180 ATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESR---GSY 236
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L + A +P + +V + +LD+NDN P F+ YN+S+ E G V+ VMA+D
Sbjct: 237 QLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASD 296
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSG 359
D G+N + TY L + + F+++P +G
Sbjct: 297 NDLGDNSKITYYLAETEHQFTVNPETG 323
Score = 79.8 bits (188), Expect = 5e-13
Identities = 57/159 (35%), Positives = 81/159 (50%), Gaps = 11/159 (6%)
Query: 218 IHAIDQDLGV-GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ AID+D+ Y +I+GN ++ F +D G + LD + + +T+ L +
Sbjct: 3567 VKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDRE-----ETSTYNLVI 3621
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P +T A V IEL D+NDN P F + N I EN P G S++ ++A+D D
Sbjct: 3622 GAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLP 3681
Query: 337 EN-GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
N G FTYQL K S+D SG VR+ T DRE
Sbjct: 3682 RNGGPFTYQLIGGKHKSWLSVDRNSG--VVRSTTSFDRE 3718
Score = 79.4 bits (187), Expect = 7e-13
Identities = 122/469 (26%), Positives = 187/469 (39%), Gaps = 41/469 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + + DANDN PV + +Y + +I VKA D D G NG V+Y
Sbjct: 2790 LRSVTLITLNVTDANDNAPV-MEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYR 2848
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
LQ + T F+I +G + E G +A VEA DQ A V
Sbjct: 2849 LQNDFDGT----FEIT-ESGEIYTRMRLDREEIGDYAFVVEAVDQGV---PHMTGTASVL 2900
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ + +K D P + V N IG+ V ++ +D + +
Sbjct: 2901 LHLL-----DKNDNPPKFTRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENP 2955
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G F +E +SG ITV L R + Y + VA + T T+ + D ND
Sbjct: 2956 GEKFRIEPQSGNITVAGHLDREQQDEYILKVVA--SDGAWRAETPITITIQDQNDNAP-- 3011
Query: 677 LKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ HS F E + A +GQI T+ G +V Q I A
Sbjct: 3012 -EFEHSFYSFSFPELQQSIALVGQIIATDRDK---QGPNSVISYSLQQPSPMFSIDPA-T 3066
Query: 736 GTIFTQKPLD-------REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G +F++K + R ++Y +TV+A N G V I I D ++NPP FE
Sbjct: 3067 GEVFSKKAVRFKHSQYVRSPENMYALTVLATDN-GKPPLYSECLVNINIVDAHNNPPKFE 3125
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATD-ADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
A Y + +++ G I + A D D GTN + + +F V + G +
Sbjct: 3126 QAEYLAPLPQDAVRGQRIVR---VHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWIT 3182
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
+ + Y+L + A D G S E ++I++ EN + P F+
Sbjct: 3183 LV-KPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFS 3230
Score = 77.4 bits (182), Expect = 3e-12
Identities = 79/311 (25%), Positives = 131/311 (42%), Gaps = 28/311 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT------VPR 136
+T+ I D+NDN P FLD+PY V E T ++ + T PL +
Sbjct: 2370 LTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDAD-TPPLNSQVRYFLKE 2428
Query: 137 GLTIFKDIRAFDRD----KPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYD 191
G + I A D KP Y++ + D G L + ++ +V D +
Sbjct: 2429 GDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTG---IVRVEVQDIN 2485
Query: 192 AGDKEFQLVIMASGKRIH----KEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D F+L + R + +L P A D+D G+ A LR+ L+ G F +D
Sbjct: 2486 DNDPVFELQSYHATVRENLPSGTHVLTPR---ATDKDEGLNAKLRFNLL-GEHMHRFHID 2541
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
S G + LD + L Q S + P + + + I + D+NDN+P+F+
Sbjct: 2542 SETGEISTATTLDRE---ETSVYHLTLMAQDSSITEP-RASSVNLTISVSDVNDNIPKFD 2597
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQ 366
YN+++ E + G V A D D GEN Y + + F I+ ++G ++ + +
Sbjct: 2598 STTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLE 2657
Query: 367 TVLDREAHSSL 377
++H L
Sbjct: 2658 LKTKTKSHDDL 2668
Score = 77.0 bits (181), Expect = 4e-12
Identities = 92/393 (23%), Positives = 170/393 (43%), Gaps = 32/393 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + S+ N+ V +L N+ P F+ ++ F + + VGT +G V+A D D G++G V
Sbjct: 3416 DSSMESYANLYVHVLGVNEFYPQFLQP-VFHFDVSETSAVGTRVGAVQATDKDSGEDGRV 3474
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPA-NPSERRYSL 552
Y L +SN F+I+ NTG + VA + R L V A + + ++ +
Sbjct: 3475 YYLLVGSSN---DKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQ 3531
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYD 609
+++I+ GN P P+F+ Y + +GT V ++ D + N SY
Sbjct: 3532 VIISIQ-----DGNDP--PEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYS 3584
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--V 667
+++G + F ++ ++G I+ L R Y+ A+ +ATVH+
Sbjct: 3585 IINGNLK-QSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQ-TGSATVHIELE 3642
Query: 668 DVNDERGVLL-KGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
DVND +G + ++ EN AG +I + ++ + NG LI +
Sbjct: 3643 DVNDNGPTFTPEGLNG----YISENEPAGTSIMTLIASD-PDLPRNGGPFTYQLIGGKHK 3697
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ G + + DRE + + E + G + +TI + D+NDNP
Sbjct: 3698 SWLSVD-RNSGVVRSTTSFDREMTPILEAIIEVE-DSGKPKQKSQHLLTITVLDQNDNPS 3755
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
+ + + N + + +K+ + ++ D D
Sbjct: 3756 T-TRSLHIAVSLFNGDLPSNVKLAD-VRPNDID 3786
Score = 73.7 bits (173), Expect = 3e-11
Identities = 100/379 (26%), Positives = 170/379 (44%), Gaps = 71/379 (18%)
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
H+ +L ES ++LNISA DGG+ + V V + DVND+ P+F + YN ++
Sbjct: 221 HLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLN 280
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD--RETE 1113
E + V A+D D G N+ +TY++ ++T+ F ++P TGV+S ++ ++T
Sbjct: 281 ETALPGTPVVTVMASDNDLGDNSKITYYL--AETEHQFTVNPETGVISTTERVNCPQQTN 338
Query: 1114 DK-------YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK-HPEA 1165
K + TV ARD+G D ND+ P ++ ++ P+
Sbjct: 339 VKSSASQKSCVFTVFARDHG-SPRQDGRTYVTVNLLDTNDHDP-------IISFRFFPDG 390
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---------IGNGNGLILY 1216
++ AT++ENA GT VA V D+D I +GN L +
Sbjct: 391 GKV---------------ATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHF 435
Query: 1217 SLPQ-------RKN----QQNLGLPSLSSTAILMVTVAD------VPDEVEMSD-KPVFI 1258
L + R N ++ +G +L+ A+ T A + D +++D +PVF
Sbjct: 436 RLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFE 495
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
Y + E + S+ T+ N ++ Y IL+ N+ + F +DP G +
Sbjct: 496 KSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNEL---KWFSMDPLTGLIV 552
Query: 1317 LVRSPDREVKDTYEVIVRA 1335
DRE++DT E+ + A
Sbjct: 553 TTGPLDREIRDTVELSISA 571
Score = 72.9 bits (171), Expect = 6e-11
Identities = 49/139 (35%), Positives = 72/139 (51%), Gaps = 10/139 (7%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D DLG A Y S N + F ++ +G++ + LD + Q + ++L+V AS
Sbjct: 2938 DLDLGANANASYSF-SENPGEKFRIEPQSGNITVAGHLDRE-----QQDEYILKVVAS-- 2989
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGE 340
+ A+ + I + D NDN PEFE FY+ S E + V Q++ATD+D QG N
Sbjct: 2990 -DGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSV 3048
Query: 341 FTYQLDDPKGAFSIDPRSG 359
+Y L P FSIDP +G
Sbjct: 3049 ISYSLQQPSPMFSIDPATG 3067
Score = 72.9 bits (171), Expect = 6e-11
Identities = 53/175 (30%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G LRY + GN+R+ FS+D G + ++++LD D N V +
Sbjct: 3251 VGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLG 3310
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+PL + A + I L D+NDN P F Y+ I EN P G V Q A DKD +
Sbjct: 3311 Y----HPLSSV-AMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPK 3365
Query: 338 NG--EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
N + + P F I +S T+ + D E +++ AK + S+
Sbjct: 3366 NAIIHYAFLPSGPDRHFFIMNQSNG-TISSAVSFDYEERRIYTLQIKAKNPDSSM 3419
Score = 72.1 bits (169), Expect = 1e-10
Identities = 84/332 (25%), Positives = 137/332 (41%), Gaps = 34/332 (10%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGL 138
+++T+ + DVNDN+P F T Y+V V E GE F + G + + T+
Sbjct: 2580 VNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRD 2639
Query: 139 TIFKDIRA--------FDRDKPNTPNSDVHYSIV-SGNDDGHFALESSHKPVLLLRK--- 186
+ DI + + D+ Y+IV S D G +L S + ++LR
Sbjct: 2640 QHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPEL 2699
Query: 187 --VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
Y A + GK I K + A G+ +RY + G
Sbjct: 2700 FPTFAYMANSHFAMSEDVRPGKMITK-------VSATSPKKGLVGKIRYAIAGGIMGDSL 2752
Query: 245 SLDSVNGSLFLEKE-LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
+D +G L + ++ LD + H + + ++A+ + P + + + + D NDN
Sbjct: 2753 RVDPNSGLLSVGQDGLDYELTH-----LYEIWIEAADGDTPSLRSVTLITLNVTDANDNA 2807
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLT 362
P E YN ++E + V A+D+D G+NG Y+L +D G F I SG +
Sbjct: 2808 PVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEI-TESGEIY 2866
Query: 363 VRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
R + LDRE V A + P + GT
Sbjct: 2867 TRMR--LDREEIGDYAFVVEAVDQGVPHMTGT 2896
Score = 70.5 bits (165), Expect = 3e-10
Identities = 47/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D G+ ++SGN+ F L+ + LD E + + L V A
Sbjct: 413 DSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDRE---EIGKYNLTVVAMDQ 469
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
P +T A + I++ D+ND+ P FE Y+ + E P G V + ATD+D G N +
Sbjct: 470 GTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQV 529
Query: 342 TYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
Y + + FS+DP +G + LDRE ++ + + A++ P+
Sbjct: 530 HYDILSGNELKWFSMDPLTGLIVTTGP--LDREIRDTVELSISARDGGPN 577
Score = 70.5 bits (165), Expect = 3e-10
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 11/168 (6%)
Query: 218 IHAID-QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+HA D QDLG + Y L++ N +FS+ +G + L K + + + L V
Sbjct: 3146 VHANDKQDLGTNE-MDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPN-----TRYELVV 3199
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+A+ P ++ + RV I + N + P F V+ Y + + EN P G ++L V ATD D G
Sbjct: 3200 RATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTG 3259
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLD--REAHSSLRMK 380
NG Y + + + FS+D R+G + ++ Q D +E H ++ ++
Sbjct: 3260 PNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQ 3307
Score = 69.7 bits (163), Expect = 6e-10
Identities = 76/296 (25%), Positives = 110/296 (37%), Gaps = 27/296 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE + T L A D+D G NG+I YE +R F + G
Sbjct: 1058 LPETTKVNTRFFALAATDIDLGDNGRISYEIIEG-------------NTERMFGVFP-DG 1103
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDN--ISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ V L E + L +S D G + + + V + V D ND+ P F + + F++
Sbjct: 1104 YLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIP 1163
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E +GK+ A D D G+NA L++ + D F I G + DRE K
Sbjct: 1164 ENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQD--FTIDTRNGFIKTLRPFDREALVK 1221
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
A V+DN + ++ K D N N
Sbjct: 1222 VSRNAEASGEDGSLRGSMAGNYMLLEATVSDNG--IPRLQDKVKVKVIVTD--VNDNAPE 1277
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
+ P Y TI E A GT + VF D D NG + YSL + L S
Sbjct: 1278 FLRAP-YHVTISEGASEGTHITHVFTQDAD--EGLNGDVYYSLAKGNEAGQFNLDS 1330
Score = 69.3 bits (162), Expect = 8e-10
Identities = 72/250 (28%), Positives = 106/250 (42%), Gaps = 22/250 (8%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E L+ A T+I ++P F F + E++ G I K++A GL G+I
Sbjct: 2681 EQSLSSKAELTVI-LRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKI 2739
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS-LPPESE--FRLNISALDGG 1023
RY + D+L V + G + V + L E + + I A DG
Sbjct: 2740 RYAIAGGIM-------GDSLRV------DPNSGLLSVGQDGLDYELTHLYEIWIEAADGD 2786
Query: 1024 --NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
+L + + V D ND+ PV ++ YN V E + +++ V A+D D G N N+
Sbjct: 2787 TPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVI 2846
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
Y +Q +D D FEI+ +G + LDRE Y V A D G
Sbjct: 2847 YRLQ-NDFDGTFEITE-SGEIYTRMRLDREEIGDYAFVVEAVDQG-VPHMTGTASVLLHL 2903
Query: 1142 XDVNDNSPKF 1151
D NDN PKF
Sbjct: 2904 LDKNDNPPKF 2913
Score = 68.9 bits (161), Expect = 1e-09
Identities = 49/172 (28%), Positives = 90/172 (52%), Gaps = 9/172 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y L+ ++ K F +D+ G +++ + LD + ++ +
Sbjct: 3461 VQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYG 3520
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
+ + N+ T +A+V I + D ND PEF +Y +I E P G V V A DKD +
Sbjct: 3521 SIRGND---TDEAQVIISIQDGNDP-PEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRT 3576
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+N +F+Y + + K +F ID ++G ++ ++ LDRE S+ + + A +T
Sbjct: 3577 QNNQFSYSIINGNLKQSFKIDVQTGEISTASR--LDREETSTYNLVIGAIDT 3626
Score = 68.5 bits (160), Expect = 1e-09
Identities = 53/186 (28%), Positives = 89/186 (47%), Gaps = 14/186 (7%)
Query: 219 HAIDQDLGVGATLRYELI-SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
HA D+D A + Y + SG DR F ++ NG++ D + + + LQ++
Sbjct: 3357 HAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYE-----ERRIYTLQIK 3411
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A ++ +++ A + + +L +N+ P+F ++ + E G V V ATDKD GE
Sbjct: 3412 AKNPDSSMES-YANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGE 3470
Query: 338 NGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
+G Y L + KG F ID +G + V LDRE + + + V AK S+ G
Sbjct: 3471 DGRVYYLLVGSSNDKG-FRIDTNTGLIYVARH--LDRETQNRVVLTVMAKNYG-SIRGND 3526
Query: 395 ADSQRI 400
D ++
Sbjct: 3527 TDEAQV 3532
Score = 67.7 bits (158), Expect = 2e-09
Identities = 50/169 (29%), Positives = 80/169 (47%), Gaps = 11/169 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y L + D +S G ++ LD + + + V+
Sbjct: 2832 VKASDRDSGDNGNVIYRLQNDFDGTFEITES--GEIYTRMRLDRE-----EIGDYAFVVE 2884
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P T A V + LLD NDN P+F +++++ EN G V++V ++D D G
Sbjct: 2885 AVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGA 2943
Query: 338 NGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N +Y ++P F I+P+SG +TV LDRE +KV A +
Sbjct: 2944 NANASYSFSENPGEKFRIEPQSGNITVAGH--LDREQQDEYILKVVASD 2990
Score = 67.3 bits (157), Expect = 3e-09
Identities = 57/196 (29%), Positives = 88/196 (44%), Gaps = 24/196 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+P GT ++ A D D GLN ++R+ E + R+ + +E G
Sbjct: 2500 VRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGE-------------HMHRFHIDSET-G 2545
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLN---DNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ A +L E S + L + A D ++++ + V DVND+ P F T YN V
Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + A D D G+NA + Y I D F+I+ TGV+S EL +T+
Sbjct: 2606 PERISKGEFVFGARALDLDDGENAVVHYTISGRDQHY-FDINTKTGVVSTKLELKTKTKS 2664
Query: 1115 ----KYILTVVARDNG 1126
Y + + A D G
Sbjct: 2665 HDDLTYTIVISAMDQG 2680
Score = 66.1 bits (154), Expect = 7e-09
Identities = 42/136 (30%), Positives = 74/136 (54%), Gaps = 11/136 (8%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
++ + L+ G+D K F L+ G L L LD + + + + L+++ S + ++ +
Sbjct: 1855 SVTFLLMDGHDGK-FLLEPSTGKLILNDTLDRETK-----SKYELRIRVS---DGVQYTE 1905
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DD 347
A I++ D NDN P FE Y+ I EN G+ V Q++A D D G+N + +Y + D
Sbjct: 1906 AYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDW 1965
Query: 348 PKGAFSIDPRSGWLTV 363
FS++P++G LT+
Sbjct: 1966 ANDVFSLNPQTGMLTL 1981
Score = 64.5 bits (150), Expect = 2e-08
Identities = 54/183 (29%), Positives = 83/183 (45%), Gaps = 19/183 (10%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE R Y++ + A + G G QV + I D NDNPP+F+H+ Y + E + G
Sbjct: 228 LDRESRGSYQLNISAR-DGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPG 286
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T + + A+D D G N+ Y L E + F V+ TGV+ + ++ ++ K
Sbjct: 287 TPVV---TVMASDNDLGDNSKITYYL-AETEHQFTVNPETGVIS-TTERVNCPQQTNVKS 341
Query: 864 S---------LVARDTGGLSSEAELIIMIG--DENDNKP--EFNQIEENSKVRIHRETKL 910
S + ARD G + + + D ND+ P F + KV E +
Sbjct: 342 SASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAV 401
Query: 911 NGT 913
NGT
Sbjct: 402 NGT 404
Score = 63.7 bits (148), Expect = 4e-08
Identities = 112/471 (23%), Positives = 188/471 (39%), Gaps = 38/471 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKV-GTVIGKVKAVDPDLGQ-NGMVLYDLQRTSN 504
+ +LD NDN P F+ S M++ G + V A D D N V Y L+ +
Sbjct: 2372 INILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDS 2431
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F+IN ++G +++ + E + L + A D + P +V +EV
Sbjct: 2432 ----DLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLT---GTGIVRVEVQ-- 2482
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
N D P F Y V N+ GT V R D E + ++LL E F
Sbjct: 2483 -DINDND-PVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLG--EHMHRF 2538
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLK 678
++ +G I+ L R +Y +A + + N T+ V DVND + K
Sbjct: 2539 HIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDN---IPK 2595
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ V E + +F + V + I+ + DI + G +
Sbjct: 2596 FDSTTYNVAVPERISKGEF--VFGARALDLDDGENAVVHYTISGRDQHYFDIN-TKTGVV 2652
Query: 739 FTQKPLDREKR---DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
T+ L + + D+ VI+ ++G S + ++T+ + + P F + F
Sbjct: 2653 STKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPP-ELFPTFAYMANSHF 2711
Query: 796 IM-ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSL 853
M E+ + G KM + AT +G Y + G + VD N+G++ D L
Sbjct: 2712 AMSEDVRPG---KMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGL 2768
Query: 854 DREKKIMYKLSLVARD--TGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
D E +Y++ + A D T L S + + + D NDN P Q+ N++V
Sbjct: 2769 DYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEV 2819
Score = 62.9 bits (146), Expect = 7e-08
Identities = 98/394 (24%), Positives = 158/394 (40%), Gaps = 62/394 (15%)
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
R +G V + N+++ Y I D F I +G ++ LDRE + Y LT++
Sbjct: 848 REVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRLTIL 907
Query: 1122 ARDNGXXXXXXXXXXXXX-----XXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
A + D+NDN+P F A D E++ + +
Sbjct: 908 ASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVF-ALDR-------ESEPTISLPENAA 959
Query: 1177 MMIPVYKATIEE-NAPIGTTVAKVFANDTDF---IGNGNGLILYSLPQRKNQQNL----- 1227
+ +Y + + + +A + + ++ N+ + IG G++ P R +L
Sbjct: 960 VGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVEL 1019
Query: 1228 -----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
G P LSS L V +ADV D PVF YE + E +L T
Sbjct: 1020 MATDAGSPPLSSKLSLSVLIADVNDHT-----PVFDHTSYETSLPETTKVNTRFFALAAT 1074
Query: 1283 --EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRAERQK 1339
+ +N ++ Y I+ E +T+ R F + P +G L+ VR+P DRE +D Y + V
Sbjct: 1075 DIDLGDNGRISYEII-EGNTE--RMFGVFP-DGYLF-VRAPLDREERDYYALTVS----- 1124
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGY 1399
D + V VV+ + D NDN+P+FTN +IP AP
Sbjct: 1125 ------------CRDAGQPSRSSVVPVVIHVIDENDNAPQFTNST--FTFSIPENAPADT 1170
Query: 1400 QVMQLKGA---IGHHPTASRTVRADTDELVFFER 1430
V +L IG + S T+ + T + R
Sbjct: 1171 FVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTR 1204
Score = 56.0 bits (129), Expect = 7e-06
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 13/147 (8%)
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
G +LF +D+ G L ELD +A + ++V A L +T++ +V + +L
Sbjct: 1759 GQVDRLFDIDAKLGILSTAAELDREAG----PEEYEVEVYAIALGGQPRTSRTKVRVTVL 1814
Query: 298 DLNDNLPEF-EVDF-YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSI 354
D ND+ P+F + F YN+S E+L G ++ + A D D G T+ L D G F +
Sbjct: 1815 DKNDSPPQFLDTPFVYNVS--EDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHDGKFLL 1870
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKV 381
+P +G L + N T LDRE S +++
Sbjct: 1871 EPSTGKL-ILNDT-LDRETKSKYELRI 1895
Score = 53.6 bits (123), Expect = 4e-05
Identities = 40/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Query: 208 IHKEILFPEPIHAIDQDL-GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
+ + I I A D+D G + + Y L + +FS+D G +F +K +
Sbjct: 3025 LQQSIALVGQIIATDRDKQGPNSVISYSLQQPSP--MFSIDPATGEVFSKKAVRFKHSQY 3082
Query: 267 LQA--NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS 324
+++ N + L V A+ P ++ V I ++D ++N P+FE Y + ++ G
Sbjct: 3083 VRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQR 3142
Query: 325 VLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTV 363
+++V A DK E Y L + FS+ GW+T+
Sbjct: 3143 IVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITL 3183
Score = 51.6 bits (118), Expect = 2e-04
Identities = 58/196 (29%), Positives = 88/196 (44%), Gaps = 24/196 (12%)
Query: 736 GTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G + T LDRE RD Y + V++ I +V I + D NDN P F +
Sbjct: 110 GEVKTNVVLDREGMRDHYDLVVLSSQPTYPI------EVRIKVLDVNDNSPEFPEPSIAI 163
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALF-MYTLFG---EGKEMFDVDEN-TGVVKFI 849
E++ GT + +D ATDAD G N + Y + + K N +G ++
Sbjct: 164 SFSESATSGTRLLLD---AATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYL 220
Query: 850 G----DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+LDRE + Y+L++ ARD G ++ + I D NDN P F+ + N +
Sbjct: 221 HLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSL- 279
Query: 904 IHRETKLNGTAGFTII 919
ET L GT T++
Sbjct: 280 --NETALPGTPVVTVM 293
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 18/151 (11%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F+LD V G + LD + + + L V +SQ P++ V I++LD+NDN
Sbjct: 103 FTLDPVTGEVKTNVVLDREG----MRDHYDLVVLSSQPTYPIE-----VRIKVLDVNDNS 153
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG---EFTYQLDDPKGAFSI----DP 356
PEF IS E+ +G +L ATD D GENG ++ + F + +P
Sbjct: 154 PEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANP 213
Query: 357 R--SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ +L + LDRE+ S ++ + A++
Sbjct: 214 SGDTSYLHLETTGNLDRESRGSYQLNISARD 244
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN----TFV 273
+ A D DLG + + Y L + F+++ G + + ++ + N++++ + V
Sbjct: 292 VMASDNDLGDNSKITYYLAETEHQ--FTVNPETGVISTTERVNCPQQTNVKSSASQKSCV 349
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-----ISIVENLPNGFSVLQV 328
V A +P + + V + LLD ND+ P F+ ++ EN NG V V
Sbjct: 350 FTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAV 409
Query: 329 MATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D G NG + ++ + G F ++ + VR VLDRE + V A +
Sbjct: 410 AVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMD 468
Score = 48.0 bits (109), Expect = 0.002
Identities = 42/132 (31%), Positives = 53/132 (40%), Gaps = 10/132 (7%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN-ANLTYFIQPS 1087
I VR+ V DVND+ P F + + E+ + L ATDAD G+N Y I
Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAG 199
Query: 1088 DTDLPFEISPLTGV--------LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
+ D F + L G LDRE+ Y L + ARD G
Sbjct: 200 NVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGG-SPPRFGYLQVNV 258
Query: 1140 XXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 259 TILDVNDNPPIF 270
Score = 45.6 bits (103), Expect = 0.011
Identities = 75/322 (23%), Positives = 130/322 (40%), Gaps = 27/322 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
LV + G ++ V V ++D+NDN P+F YH TV E P+G
Sbjct: 2461 LVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDE 2520
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKP----------NTPNSDVHYSIVSGNDDGHFALES 176
L L R + + + F D + + V++ + D E
Sbjct: 2521 GLNAKL---RFNLLGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSS--ITEP 2575
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVI--MASGKRIHK-EILFPEPIHAIDQDLGVGATLRY 233
V L V D + +F +A +RI K E +F A+D D G A + Y
Sbjct: 2576 RASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVF--GARALDLDDGENAVVHY 2633
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
ISG D+ F +++ G + + EL + + T+ + + A +++A +
Sbjct: 2634 -TISGRDQHYFDINTKTGVVSTKLELKTKTKSH-DDLTYTIVISAMDQGEQSLSSKAELT 2691
Query: 294 IELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKG 350
+ +L + P F + + ++ E++ G + +V AT +G G+ Y +
Sbjct: 2692 V-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGD 2750
Query: 351 AFSIDPRSGWLTVRNQTVLDRE 372
+ +DP SG L+V Q LD E
Sbjct: 2751 SLRVDPNSGLLSV-GQDGLDYE 2771
Score = 44.8 bits (101), Expect = 0.018
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 31/179 (17%)
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFK 1289
LSST + + + DV DEV PVFIS E I ENV ++++ ++ E N
Sbjct: 2147 LSSTVKVTILIKDVNDEV-----PVFISAN-ETAIMENVAINTVVIAVKAVDNDEGRNGY 2200
Query: 1290 MRYYILNENDTDIRRT----FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+ Y + D D+ ++ F ++P +G L +V + DRE++ +Y
Sbjct: 2201 IDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSY---------------- 2244
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
++ A D E + ++++RI D NDNSP F + ++ A G V+Q+
Sbjct: 2245 -LLNITARDRGEPPQSTESQLLIRILDENDNSPVF--DPKQYSASVAENASIGAMVLQV 2300
Score = 43.6 bits (98), Expect = 0.043
Identities = 19/50 (38%), Positives = 29/50 (58%)
Query: 1438 SPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+P+ATD D G+NA +R+ +L E RF ID +G + L R+ V+
Sbjct: 2512 TPRATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDREETSVY 2561
Score = 41.5 bits (93), Expect = 0.17
Identities = 44/193 (22%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G+P L + V V DV D P F+ Y + I E + + + + E
Sbjct: 1254 GIPRLQDKVKVKVIVTDVNDNA-----PEFLRAPYHVTISEGASEGTHITHVFTQDADEG 1308
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N + Y + N+ F +D G L L R DRE S+E+
Sbjct: 1309 LNGDVYYSLAKGNEAG---QFNLDSATGQLSLGRRLDRE----------------SQEIH 1349
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
H+I + L+ + + + + D NDN+P+FT + + ++ T+P G ++M+ +
Sbjct: 1350 HLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEV--SVLETSPTGTELMRFR 1407
Query: 1406 GAIGHHPTASRTV 1418
+ S+ V
Sbjct: 1408 ASDADQGVNSQVV 1420
Score = 41.1 bits (92), Expect = 0.23
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 17/192 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E P+GT + + A+D D +R + N Y S ++ + +K+ F I+ + G
Sbjct: 3554 ISEAAPVGTKVTTVKAIDKD------VRTQNNQFSY---SIINGN---LKQSFKIDVQTG 3601
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A L E S + L I A+D G + +V + ++DVND+ P F N +
Sbjct: 3602 EISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYIS 3661
Query: 1056 EAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + + + A+D D +N TY + + +GV+ DRE
Sbjct: 3662 ENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTP 3721
Query: 1115 KYILTVVARDNG 1126
+ D+G
Sbjct: 3722 ILEAIIEVEDSG 3733
Score = 36.7 bits (81), Expect = 4.9
Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 1436 LTSPQATDSDIGINADIRYQILN-EQAPRFAIDPVSGTVRVVAALARD 1482
+ S ATD D G+NA + Y IL+ + F++DP++G + L R+
Sbjct: 513 VASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDRE 560
>UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3;
Sophophora|Rep: Cadherin 89D precursor - Drosophila
melanogaster (Fruit fly)
Length = 2240
Score = 238 bits (583), Expect = 7e-61
Identities = 141/308 (45%), Positives = 182/308 (59%), Gaps = 36/308 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V VE+TLLD NDN P F NLYEF + NA G VIG+V A DPD G NG +LY+LQ
Sbjct: 510 SKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQ 569
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
R PF+++ GT+ V P+ GR A+FVEA+DQP NPSERR+SLAV+TIEV
Sbjct: 570 RPKGSGYI-PFRLDNKNGTIYVG-GPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVY 627
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLHGYEEGVP 619
DF+GAPYEFWVG+N +GTSVGQ+R +E D + YDLLH Y EGVP
Sbjct: 628 ATI---DDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVP 684
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS---------------------- 657
FA+EERSG+ITV+ +LS + R +Y FEAVA AN S
Sbjct: 685 FAIEERSGIITVIRELSEFKRKVYQFEAVANYLFANSSQSLVMSRSSSPLTTIASPAELS 744
Query: 658 ----IVTNATVHVVDVNDE----RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
++TN T+H+V+ ++ R V+ + + I FHV+EN G IGQ+ + N ++
Sbjct: 745 DEGVLITNLTIHIVNKPEQKVPLRPVIEEINMNVIHFHVEENVVGGIIGQLLYKNGINLV 804
Query: 710 GNGTGNVR 717
N G R
Sbjct: 805 NNELGTYR 812
Score = 227 bits (556), Expect = 1e-57
Identities = 168/420 (40%), Positives = 229/420 (54%), Gaps = 53/420 (12%)
Query: 5 RKNLNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGC----- 59
R L+ D D F + N T + V LA+S++ LVD D P+N++KFR+ C
Sbjct: 96 RSTAALKGADASGDHKYFNLTEHNATTLVVSLARSLERLVDRDVPRNLLKFRILCAGKQE 155
Query: 60 DFDEGDDL---VRIGAGLNQISAYLSVTVYIEDVNDNVP----IFL----------DTP- 101
+EG L V I + +L+V Y+ DV++N IF +TP
Sbjct: 156 KLEEGSYLSITVYIEDVNDNAPEFLNVP-YVVDVDENTSIESIIFEGVQAFDRDKPNTPN 214
Query: 102 --YHV---TVDELTPTGEKAFIFLIAPIGPSLTIP--LTVPRGLTIFK-DIRAFDRDKP- 152
H TV E + L +P P L + L G+ FK I A+DR P
Sbjct: 215 SEVHFSMSTVPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPA 274
Query: 153 NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI 212
N N+ + ++ +D P V Y EF + +G I +
Sbjct: 275 NQANTTITINVRDVDD----------LPPKFTEGV--YRTRINEFYPM---TGVPIRIPL 319
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
F PI A DQD + A+L Y++ISGN+R+LF ++ NG ++L+KE+DL+ E +L NTF
Sbjct: 320 YFAPPIMAFDQD-SLNASLVYDIISGNERQLFRVNPHNGVMYLQKEIDLE-EESLPGNTF 377
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VLQ++A Q +NPLK A AR+E+E+LDLNDN+PEFE D+YNISIVENLP GFSVLQV A D
Sbjct: 378 VLQLEARQKDNPLKKALARIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVD 437
Query: 333 KDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+DQGEN EF Y L D GAF ID R+GW+TVR+ +LDRE S+++ V A E NPS
Sbjct: 438 RDQGENSEFLYNLVETKDAAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPS 497
Score = 207 bits (506), Expect = 2e-51
Identities = 115/333 (34%), Positives = 175/333 (52%), Gaps = 9/333 (2%)
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
I + + + RE + G + K + + + PLF I E+ P+GT +++L+A
Sbjct: 1136 IPGSPRFNVDRERSVGAGLG-VVARAKSRRRMVRALTTKCPLFAIYEDTPVGTKVLQLSA 1194
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRL 1015
D D G N + YE E + + +YF I++ G + V L E L
Sbjct: 1195 SDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELSVNYPLSANIEIML 1254
Query: 1016 NISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
N++ D L D+ +R V DVN+H P FKK+WY+F+ E +Y VLG++ A D DFG
Sbjct: 1255 NLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDFG 1314
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG-XXXXXXXX 1134
+NAN+TY + SD+ LPF I P +GVL + G+LDRE +DKY V+A DN
Sbjct: 1315 ENANITYTL--SDSHLPFTIKPASGVLKIGGQLDRELKDKYSFQVIATDNAPVMQRMSSS 1372
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D+NDN P+F +D+ +A + + +M+PVYKA ++ + GT
Sbjct: 1373 VDVEVNVLDINDNRPEFIGYDD-----QTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGT 1427
Query: 1195 TVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
V ++ A D D +GNGNGL+LYS+ ++ Q L
Sbjct: 1428 FVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPL 1460
Score = 132 bits (320), Expect = 5e-29
Identities = 63/137 (45%), Positives = 89/137 (64%)
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
+ G+ +R++IANQQ+V + I+I EDGT+ T LDRE++ Y +TVI E++ G++SG
Sbjct: 848 LVGDANIKLRYIIANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSG 907
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
AGIYQV I ++D NDN P F TY G I EN +GTE+ M++ I DADEG NA F
Sbjct: 908 AGIYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRV 967
Query: 828 TLFGEGKEMFDVDENTG 844
L G+ + F ++ G
Sbjct: 968 QLQGDYSDEFSIEYVNG 984
Score = 113 bits (272), Expect = 4e-23
Identities = 65/193 (33%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Query: 1226 NLGLPSLSSTAILMVT-----VADVPDEVEMSDKP----VFISRYYELEIEENVNAPVEL 1276
++G P+LS+TAI++V V D P + P VF YYE+++ EN AP+E+
Sbjct: 1493 DVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEV 1552
Query: 1277 VSLNLTE--HYENFKMRYYILNEND-TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
+ LNL+ + EN++ ++ D TD F D +N LY ++ DRE Y++ +
Sbjct: 1553 MRLNLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRI 1612
Query: 1334 RAER-QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
RA+R + +R + YPV ++ +EG++ + +++V I D NDN+PKF +P+V +P
Sbjct: 1613 RADRLSREARNYARVSYPVVDERIEGLSLNECRILVHIADENDNAPKFRGNGQPIVAVLP 1672
Query: 1393 TTAPFGYQVMQLK 1405
+A FGY V +++
Sbjct: 1673 QSASFGYPVTRVE 1685
Score = 84.6 bits (200), Expect = 2e-14
Identities = 91/335 (27%), Positives = 144/335 (42%), Gaps = 26/335 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ +EV +LD NDN P F ++ Y S+ N G + +V AVD D G+N LY+L
Sbjct: 393 ALARIEVEVLDLNDNVPEF-EADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLV 451
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSE------RRYSL 552
T + F+I+ TG ++V + +L E R ++ + NPS ++
Sbjct: 452 ETKD--AAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGP 509
Query: 553 AVVTIEVT-RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYD 609
+ V +E+T T N P G YEF V N G +GQ+ +D E + Y+
Sbjct: 510 SKVQVEITLLDTNDNTPKFEH--GNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYE 567
Query: 610 LLHGYEEG-VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHV 666
L G +PF ++ ++G I V L R R EA N + + A T+ V
Sbjct: 568 LQRPKGSGYIPFRLDNKNGTIYVGGPLRR-GRIAVFVEATDQPTNPSERRFSLAVITIEV 626
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
D++ + GA P F V N+ G ++GQ+ + IY G + L+ +
Sbjct: 627 YATIDDQAIDFVGA--PYEFWVGANTPLGTSVGQV---RTTLIYEGGDEIMYDLLHTYSE 681
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF 760
G I + L KR VY+ +A +
Sbjct: 682 GVPFAIEERSGIITVIRELSEFKRKVYQFEAVANY 716
Score = 83.8 bits (198), Expect = 3e-14
Identities = 58/184 (31%), Positives = 95/184 (51%), Gaps = 15/184 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKE--LDLDAEHNLQANTFVL 274
++A+D+D G + Y L+ D F +DS G + + + LD + ++Q N L
Sbjct: 433 VNAVDRDQGENSEFLYNLVETKDAAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEAL 492
Query: 275 QVQASQLNNP-LKT---AQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVM 329
+ S L++ LK ++ +VEI LLD NDN P+FE + Y + N P G+ + QV+
Sbjct: 493 ERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVV 552
Query: 330 ATDKDQGENGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A D D+G NG Y+L PKG+ F +D ++G + V R ++ ++ +
Sbjct: 553 AHDPDEGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYVGGPL---RRGRIAVFVEATDQP 609
Query: 386 TNPS 389
TNPS
Sbjct: 610 TNPS 613
Score = 62.1 bits (144), Expect = 1e-07
Identities = 113/486 (23%), Positives = 198/486 (40%), Gaps = 77/486 (15%)
Query: 448 TLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTI 507
T++D N++ P F S Y F +V+G++ A+D D G+N + Y L S+L
Sbjct: 1273 TVMDVNNHAPTFKKS-WYSFDTPEGEYKDSVLGQLTAIDMDFGENANITYTLS-DSHL-- 1328
Query: 508 TSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEV------ 559
PF I P +G + + L+ +++ V A+D A +R S V + V
Sbjct: 1329 --PFTIKPASGVLKIGGQLDRELKDKYSFQVIATDN-APVMQRMSSSVDVEVNVLDINDN 1385
Query: 560 -------TRGTKGNK--PDIPD--FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--- 605
TK K P + D M Y+ ++ + GT V Q+ D +
Sbjct: 1386 RPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNG 1445
Query: 606 -VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
V Y + H + F ++ R G I+ + ++ YN Y+ V++ + S +AT
Sbjct: 1446 LVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYND--YEHLNVSVIASDVGSPALSATA 1503
Query: 665 HVVDVNDERGVLLKGAHSP-------------IIFHVKENSAGAAIGQIFHTNMSSIYGN 711
V+ + V +P + VK A ++ N+S+ G
Sbjct: 1504 IVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEVMRLNLSA--GL 1561
Query: 712 GTGNVRFLIANQQDVTDDIA------IAEDGTIFTQKPLDREKRDVYRMTVIAE-FNKGV 764
N R+ + ++ + + A A++ ++ KP DRE Y++ + A+ ++
Sbjct: 1562 NPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRIRADRLSREA 1621
Query: 765 --------------ISGAGIYQVTI--YIEDENDNPPVF--EHATYEGFIMENSKIGTEI 806
I G + + I +I DENDN P F + +++ G +
Sbjct: 1622 RNYARVSYPVVDERIEGLSLNECRILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPV 1681
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
++A D DEG NA Y L E +F +DE +G ++ +G+ L R + I Y +
Sbjct: 1682 TR---VEANDLDEGLNAEIRYRLLNEPARLFGIDELSGNIRLLGE-LSRTEHI-YGFDVK 1736
Query: 867 ARDTGG 872
A D G
Sbjct: 1737 ATDRMG 1742
Score = 61.7 bits (143), Expect = 2e-07
Identities = 107/462 (23%), Positives = 188/462 (40%), Gaps = 60/462 (12%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVP------IFLDTPYHVTVDELTPTGEKAFIFLIAP 123
I A +S Y +TV + DVNDN P +F D+ + + E T E F+ +
Sbjct: 1060 IAADTGGLSGYAHLTVLVADVNDNAPMFERISVFKDS--RLEIREYTTDMEIYFVESSSG 1117
Query: 124 I-GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
+ P T + + F+ D+ + + + +V+ + +
Sbjct: 1118 MTAPQATAAMMLAPPPYHIPGSPRFNVDRERSVGAGL--GVVARAKSRRRMVRALTTKCP 1175
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
L D G K QL AS + K L +H Q V T ++ + K
Sbjct: 1176 LFAIYEDTPVGTKVLQL--SASDEDFGKNAL----LHYELQGEQVERTPGMPMLRVHGVK 1229
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F++D ++G L + L + E + N V + LK + + ++D+N++
Sbjct: 1230 YFAIDKLSGELSVNYPLSANIE--IMLNLTVTDIDG------LKDSTC-LRFTVMDVNNH 1280
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P F+ +Y+ E + Q+ A D D GEN TY L D F+I P SG L
Sbjct: 1281 APTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTIKPASGVLK 1340
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFP 422
+ Q LDRE +V A + P + Q + ++ +E
Sbjct: 1341 IGGQ--LDRELKDKYSFQVIATDNAPVM---------------QRMSSSVDVEVNVLDIN 1383
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
D + E I YD+Q + V + + + + +P +Y+ + + + GT + ++
Sbjct: 1384 D---NRPEFIG-YDDQTKA-----VKFIPSVADRTLMLP--VYKAYLDRSTQPGTFVRQL 1432
Query: 483 KAVDPD-LGQ-NGMVLYDLQRTSNLTITSP-FKINPNTGTVS 521
A+D D +G NG+VLY ++ + +P F+I+ GT+S
Sbjct: 1433 TAIDKDNVGNGNGLVLYSIRHQE---MQAPLFQIDSRDGTIS 1471
Score = 57.6 bits (133), Expect = 2e-06
Identities = 55/183 (30%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEV-KRYFVINERH 998
I EN+P G +++++NA+D D G N + Y + +K +A A + R I R
Sbjct: 420 IVENLPTGFSVLQVNAVDRDQGENSEFLYN------LVETKDAAGAFRIDSRTGWITVRD 473
Query: 999 GHVI---VARSLPPESE-FRLNISALDGGNLN----DNISVRVFVKDVNDHFPVFKK-TW 1049
++ RS+ E N S LD +L + V + + D ND+ P F+
Sbjct: 474 DRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKFEHGNL 533
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-PSDTD-LPFEISPLTGVLSVNGE 1107
Y F V T V+G+V A D D G N +L Y +Q P + +PF + G + V G
Sbjct: 534 YEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYVGGP 593
Query: 1108 LDR 1110
L R
Sbjct: 594 LRR 596
Score = 55.6 bits (128), Expect = 1e-05
Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE--ENSKVRIHRET 908
LDREK+ +Y L ++A DTGGLS A L +++ D NDN P F +I ++S++ I T
Sbjct: 1047 LDREKQQLYNLKIIAADTGGLSGYAHLTVLVADVNDNAPMFERISVFKDSRLEIREYT 1104
Score = 54.4 bits (125), Expect = 2e-05
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVFGFXXXXXX 1495
+T +A D D G+NA+IRY++LNE A F ID +SG +R++ L+R ++GF
Sbjct: 1681 VTRVEANDLDEGLNAEIRYRLLNEPARLFGIDELSGNIRLLGELSR-TEHIYGFDVKATD 1739
Query: 1496 XXXXXXXXXXXXNVFV 1511
NVFV
Sbjct: 1740 RMGADDGRSGIVNVFV 1755
Score = 54.0 bits (124), Expect = 3e-05
Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 20/176 (11%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFN---KGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+G ++ QK +D E+ + T + + K + ++ + + D NDN P FE
Sbjct: 356 NGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVLDLNDNVPEFEADY 415
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF--GEGKEMFDVDENTGVVKFI 849
Y I+EN G + + A D D+G N+ F+Y L + F +D TG +
Sbjct: 416 YNISIVENLPTGFSVLQ---VNAVDRDQGENSEFLYNLVETKDAAGAFRIDSRTGWITVR 472
Query: 850 GDS-LDREKKIMYKLSLVA--RDTGGLS---------SEAELIIMIGDENDNKPEF 893
D LDRE++ +L++ A R+ L S+ ++ I + D NDN P+F
Sbjct: 473 DDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKF 528
Score = 53.6 bits (123), Expect = 4e-05
Identities = 56/188 (29%), Positives = 86/188 (45%), Gaps = 25/188 (13%)
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY--EN 1287
P + A + V V D+ D V P F + YY + I EN+ ++ +N + EN
Sbjct: 389 PLKKALARIEVEVLDLNDNV-----PEFEADYYNISIVENLPTGFSVLQVNAVDRDQGEN 443
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNG--TLYLVRSPDREVKDTYEVIVRA-ERQKYSREL 1344
+ Y ++ D F ID R G T+ R DRE + + ++ V A ER +
Sbjct: 444 SEFLYNLVETKDA--AGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDD 501
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
H+ P G +K V+V + + D NDN+PKF +GN +P AP GY + Q+
Sbjct: 502 KHLKKP-------GPSK--VQVEITLLDTNDNTPKFEHGNL-YEFKVPINAPTGYVIGQV 551
Query: 1405 KGAIGHHP 1412
+ H P
Sbjct: 552 ---VAHDP 556
Score = 53.6 bits (123), Expect = 4e-05
Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D N++ P F+ + Y E + + + A D D G NA YTL +
Sbjct: 1274 VMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQ---LTAIDMDFGENANITYTL-SDSHLP 1329
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG----LSSEAELIIMIGDENDNKPE 892
F + +GV+K IG LDRE K Y ++A D +SS ++ + + D NDN+PE
Sbjct: 1330 FTIKPASGVLK-IGGQLDRELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPE 1388
Query: 893 FNQIEENSK 901
F ++ +K
Sbjct: 1389 FIGYDDQTK 1397
Score = 52.0 bits (119), Expect = 1e-04
Identities = 53/194 (27%), Positives = 83/194 (42%), Gaps = 20/194 (10%)
Query: 989 KRYFVINERHGHVIVARSLPPESE------FRLNISALDGGN-LNDNIS-VRVFVKDVND 1040
++ F +N +G + + + + E E F L + A N L ++ + V V D+ND
Sbjct: 347 RQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVLDLND 406
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLT 1099
+ P F+ +YN ++ E T + +V+A D D G+N+ Y ++ D F I T
Sbjct: 407 NVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKDAAGAFRIDSRT 466
Query: 1100 GVLSVNGE--LDRETEDKYILTVVA--------RDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
G ++V + LDRE L V A D D NDN+P
Sbjct: 467 GWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTP 526
Query: 1150 KFYAFDELLEWKHP 1163
KF L E+K P
Sbjct: 527 KF-EHGNLYEFKVP 539
Score = 46.0 bits (104), Expect = 0.008
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 17/187 (9%)
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLPNGFSVLQVMATDKDQGENGEFT 342
L + R+ + + D NDN P+F + I V ++ G+ V +V A D D+G N E
Sbjct: 1639 LSLNECRILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIR 1698
Query: 343 YQ-LDDPKGAFSIDPRSGWLTV-----RNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
Y+ L++P F ID SG + + R + + + ++ RM A + +V F
Sbjct: 1699 YRLLNEPARLFGIDELSGNIRLLGELSRTEHIYGFDVKATDRMG--ADDGRSGIVNVFVY 1756
Query: 397 SQRIAKWRR-----QPLETNAPLEKTTYVFPDKVG--TKTENIEYYDEQLMSFVNVEVTL 449
AK R P+E +E D +G + +E Y L N +
Sbjct: 1757 IINEAKQVRLVVAGMPVEVERRIEGLMEALSDAIGKDVRVRLLEPYSGGLEPATNAYIYA 1816
Query: 450 LDANDNN 456
+D + N+
Sbjct: 1817 VDPHTNS 1823
Score = 45.2 bits (102), Expect = 0.014
Identities = 60/232 (25%), Positives = 97/232 (41%), Gaps = 24/232 (10%)
Query: 940 IPENIPIGTTIIK-LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ EN I + I + + A D D F+ P +LSAD YF + H
Sbjct: 188 VDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTV--PEQLSADG---SPYFALKSPH 242
Query: 999 GHVIVA-RSLPPES---EFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFKKTWYNF 1052
+++ R L ++ +F+L I A D G + N ++ + V+DV+D P F + Y
Sbjct: 243 RPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTEGVYRT 302
Query: 1053 NVEEAQYTRRVLGKVDATDAD----FGQ---NANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ E V ++ A F Q NA+L Y I + F ++P GV+ +
Sbjct: 303 RINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVYDIISGNERQLFRVNPHNGVMYLQ 362
Query: 1106 GELDRETE----DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
E+D E E + ++L + AR D+NDN P+F A
Sbjct: 363 KEIDLEEESLPGNTFVLQLEARQK-DNPLKKALARIEVEVLDLNDNVPEFEA 413
Score = 44.8 bits (101), Expect = 0.018
Identities = 43/131 (32%), Positives = 58/131 (44%), Gaps = 16/131 (12%)
Query: 737 TIFTQKPLDREKRDVYRMTVIA-EFNKGVIS-------GAGIYQVTIYIEDENDNPPVFE 788
T+ + LDRE+R ++ V A E N + G QV I + D NDN P FE
Sbjct: 470 TVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKFE 529
Query: 789 HAT-YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTG 844
H YE + N+ G I + A D DEG N +Y L G G F +D G
Sbjct: 530 HGNLYEFKVPINAPTGYVIGQ---VVAHDPDEGPNGHLLYELQRPKGSGYIPFRLDNKNG 586
Query: 845 VVKFIGDSLDR 855
+ ++G L R
Sbjct: 587 TI-YVGGPLRR 596
Score = 40.7 bits (91), Expect = 0.30
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 15/154 (9%)
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY-----EGFIMENSKIGTEI 806
+++ + A +++G + +TI + D +D PP F Y E + M I +
Sbjct: 261 FKLPIFA-WDRGTPANQANTTITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPL 319
Query: 807 KMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIM----Y 861
I A D D NA +Y + G +++F V+ + GV+ ++ +D E++ + +
Sbjct: 320 YFAPPIMAFDQD-SLNASLVYDIISGNERQLFRVNPHNGVM-YLQKEIDLEEESLPGNTF 377
Query: 862 KLSLVAR--DTGGLSSEAELIIMIGDENDNKPEF 893
L L AR D + A + + + D NDN PEF
Sbjct: 378 VLQLEARQKDNPLKKALARIEVEVLDLNDNVPEF 411
Score = 39.9 bits (89), Expect = 0.53
Identities = 55/255 (21%), Positives = 103/255 (40%), Gaps = 25/255 (9%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A ++ I N +++ + S+ L LD E V+ ++ L +
Sbjct: 852 ANIKLRYIIANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIY 911
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ---VMATDKDQGENGEFTYQL 345
Q ++++ D+NDN P+F Y I EN G + ++ D D+G N EF QL
Sbjct: 912 QVNIKVD--DVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQL 969
Query: 346 D-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWR 404
D FSI+ +G T + H + A ++ + D + +
Sbjct: 970 QGDYSDEFSIEYVNG-------TSSENSTHHKMPSTTGAFNIF-NLTDQWNDEFKYQELH 1021
Query: 405 RQPLETNAPLEKTTYV---FPDKVGTKTENIEYYDEQLMS--------FVNVEVTLLDAN 453
++TN L Y + K G E + Y+ ++++ + ++ V + D N
Sbjct: 1022 TTFMQTNFKLSSGPYFRISYTGKRGLDREKQQLYNLKIIAADTGGLSGYAHLTVLVADVN 1081
Query: 454 DNNPVFVPSNLYEFS 468
DN P+F ++++ S
Sbjct: 1082 DNAPMFERISVFKDS 1096
Score = 39.1 bits (87), Expect = 0.92
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++ LDREK+ +Y + +IA G+ +G +T+ + D NDN P+FE
Sbjct: 1044 KRGLDREKQQLYNLKIIAADTGGL---SGYAHLTVLVADVNDNAPMFE 1088
Score = 38.7 bits (86), Expect = 1.2
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 15/168 (8%)
Query: 741 QKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
++ +DR+ R++ + ++ + + +T+YIED NDN P F + Y + EN
Sbjct: 132 ERLVDRDVPRNLLKFRILCAGKQEKLEEGSYLSITVYIEDVNDNAPEFLNVPYVVDVDEN 191
Query: 800 SKIGTEIKMDNIIKATDADEGT--NALFMYT-------LFGEGKEMFDVDENTGVVKFIG 850
+ I E + ++A D D+ N+ ++ L +G F + + +
Sbjct: 192 TSI--ESIIFEGVQAFDRDKPNTPNSEVHFSMSTVPEQLSADGSPYFALKSPHRPLLILK 249
Query: 851 DSLDREKKI-MYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQ 895
LD + I +KL + A D G +++A I I D +D P+F +
Sbjct: 250 RELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTE 297
Score = 37.1 bits (82), Expect = 3.7
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 19/94 (20%)
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N K+RY I N+ + + + + + +GTL + DRE + +YE+ V E YS L
Sbjct: 853 NIKLRYIIANQQEV-VNKISITE--DGTLLTLTGLDREQQPSYELTVIVE---YSTGL-- 904
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ G Y V +++ DVNDN+PKF
Sbjct: 905 ---------VSGAGIYQVN--IKVDDVNDNAPKF 927
Score = 36.7 bits (81), Expect = 4.9
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM---FDVDENTGVVKFIGDS 852
I E++ +GT++ + A+D D G NAL Y L GE E + GV F D
Sbjct: 1179 IYEDTPVGTKVLQ---LSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDK 1235
Query: 853 LDREKKIMYKLS--------LVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
L E + Y LS L D GL L + D N++ P F +
Sbjct: 1236 LSGELSVNYPLSANIEIMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKK 1286
>UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep:
ENSANGP00000011254 - Anopheles gambiae str. PEST
Length = 1821
Score = 221 bits (540), Expect = 1e-55
Identities = 126/292 (43%), Positives = 181/292 (61%), Gaps = 31/292 (10%)
Query: 430 ENIEYYDEQL-MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
E +E YD V VE+TLLD NDN P F LYEF NA +G+ +G+++A+DPD
Sbjct: 436 ERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPD 495
Query: 489 LGQNGMVLYDLQRTS-NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSE 547
NG + Y ++ NL I PF ++P+TG + V+E+ + G+ A FVEA DQP NPSE
Sbjct: 496 DLGNGKIQYSIKNVRPNLVI--PFLLDPDTGDIRVSEA-LTYGKIAFFVEARDQPQNPSE 552
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN-DAFEQNDV 606
R+++A+VTI++ + DI +F+GAPYEFWVG++ IG+SVGQIR D ++
Sbjct: 553 SRFNVALVTIDIVCQSI---EDI-EFIGAPYEFWVGADAAIGSSVGQIRTTFDMVSDEEI 608
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLS------- 657
+DLLH Y EGVPFA+EERSG++TV++ + +++R Y+FE V L ++A +
Sbjct: 609 FFDLLHSYPEGVPFAIEERSGIVTVIESMEKFDRRCYEFETVVSYLPDSAGKNVEQLTPE 668
Query: 658 --------IVTNATVHVVDVNDERGVLLKGAH-SPIIFHVKENSAGAAIGQI 700
IVTN T+HV+ N +LL+G + +PI F VKEN IGQ+
Sbjct: 669 AYNSLEKIIVTNVTIHVIKHN---FMLLRGTNATPIEFRVKENKPNTMIGQL 717
Score = 215 bits (524), Expect = 1e-53
Identities = 105/184 (57%), Positives = 138/184 (75%), Gaps = 4/184 (2%)
Query: 204 SGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
+GK IH + PI A DQD + TL Y +++GN+R+LF + G LFL+KE+DLD+
Sbjct: 255 TGKPIHIPLYIEPPIMAFDQD-SLNETLVYGIVAGNERQLFWISPETGVLFLQKEIDLDS 313
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
E +L NTF LQ++A Q+N+P K+A ARV+IE++DLNDN+PEFEVD YNISI+ENLP GF
Sbjct: 314 E-SLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGF 372
Query: 324 SVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
S+LQV A D+DQGEN EF Y L ++PKGAF ID SGW+ VR++T LD+E SSL+M V
Sbjct: 373 SILQVNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNV 432
Query: 382 YAKE 385
+A E
Sbjct: 433 HAVE 436
Score = 198 bits (484), Expect = 7e-49
Identities = 115/284 (40%), Positives = 162/284 (57%), Gaps = 22/284 (7%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F +PEN+ +G I KL A D D N ++ YE + ++L++ E YF I+
Sbjct: 1100 FALPENVEVGKVIFKLTANDDDFEKNSKVFYEV-----VGQTELNSG--ERVSYFRIDRN 1152
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+G + VA LPPE++ +LNI+A D G L+D + V+ V DVND+ PVF+K WY FNV+E
Sbjct: 1153 NGELRVANRLPPETDVKLNITAKDVGGLSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEG 1212
Query: 1058 QY--TRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
Y T + +G+V A D D G N N+TY I D +PF ISPL G + V+GE+DRE
Sbjct: 1213 SYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKIPFSISPLDGTIRVSGEIDREMIA 1272
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y V+A DN D NDN+P+F A+D+L S+ N
Sbjct: 1273 SYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDL----------RSDRN-- 1320
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
++ +PVY A ++ NA +GT V +V A D+DF NGNGL++YSL
Sbjct: 1321 NIKRLPVYVAYLDVNAKVGTFVKQVMARDSDFRENGNGLVIYSL 1364
Score = 123 bits (297), Expect = 3e-26
Identities = 76/205 (37%), Positives = 113/205 (55%), Gaps = 33/205 (16%)
Query: 5 RKNLNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEG 64
R ++ + + D F +++N T VSVIL +S+D LVDSD PQ+++KF + C
Sbjct: 40 RNSILIPRTENSSDYEYFKLKEINSTVVSVILNRSLDGLVDSDDPQSILKFSVFCSGTSA 99
Query: 65 DDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI 124
+ S++ ++TVYIED+NDN P F++ PY VT+DE TP
Sbjct: 100 T------SAKQDNSSFFTITVYIEDINDNDPEFINLPYVVTLDESTPIE----------- 142
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVS---GNDDGHFALESSHKPV 181
TV +F I+A DRDKPNTPNSD+ Y++ + + D F LE S +P
Sbjct: 143 --------TV-----VFNRIKAIDRDKPNTPNSDLEYALAAKHMKSGDFPFRLEGSQRPS 189
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGK 206
L+L++ LDYDAG + + I+AS +
Sbjct: 190 LVLQRALDYDAGWRSMSVQIVASDR 214
Score = 114 bits (274), Expect = 2e-23
Identities = 60/186 (32%), Positives = 115/186 (61%), Gaps = 9/186 (4%)
Query: 1226 NLGLPSLSSTAILMVTV-ADVPDEVEMSDKP-VFISRYYELEIEENVNAPVELVSLNLTE 1283
+ G P SS A+L+V + D + + ++P +F +YYE+E+ EN AP ++++ L++
Sbjct: 1410 DFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYEIELRENDPAPRIVLNVTLSK 1469
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER-QKYSR 1342
Y N R+ I+ + D F ID RNG+L+L+R DRE +D+Y+V +R ++ ++ +R
Sbjct: 1470 RYANDPFRWEIVGDTFDD---QFRIDERNGSLWLLRPLDREERDSYDVRIRVQKIKRETR 1526
Query: 1343 ELPHMIYPVAEDVLEGMTKY---DVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGY 1399
+P ++Y + V + +V++++++ DVNDN+P F + P+++ +P TA +GY
Sbjct: 1527 NIPSVLYALENPVKRKSHRLFDNEVEIMIKVVDVNDNAPVFRDNYGPIISVVPDTANYGY 1586
Query: 1400 QVMQLK 1405
VM+++
Sbjct: 1587 AVMKVE 1592
Score = 108 bits (259), Expect = 1e-21
Identities = 56/118 (47%), Positives = 74/118 (62%), Gaps = 1/118 (0%)
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
V++ + N DV D + + DG + T K LDREK+DV R+T+IAE+ + AGIYQV I
Sbjct: 781 VQYSLVNSYDVADTVRLTNDGKLMTIKGLDREKQDVIRVTIIAEYFYKQRTFAGIYQVVI 840
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGE 832
+EDENDNPP F + G I ENS IGTEI ++N I +D D G N+ + L GE
Sbjct: 841 VVEDENDNPPTFNQPFFLGVIAENSPIGTEIVLNNPIIISDMDAAGPNSEYELLLSGE 898
Score = 90.6 bits (215), Expect = 3e-16
Identities = 135/560 (24%), Positives = 232/560 (41%), Gaps = 76/560 (13%)
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTI---TSPFKINPNTGTVSV 522
+F++ N +VG VI K+ A D D +N V Y++ + L S F+I+ N G + V
Sbjct: 1099 KFALPENVEVGKVIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRV 1158
Query: 523 AESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
A E L + A D + V + + P F Y F V
Sbjct: 1159 ANRLPPETDVKLNITAKDVGGLSDMLQVQFRVYDV---------NDNAPVFEKQWYTFNV 1209
Query: 583 --GSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRY 638
GS G +GQ+R N D +V+Y L+ ++ +PF++ G I V ++ R
Sbjct: 1210 DEGSYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKIPFSISPLDGTIRVSGEIDRE 1269
Query: 639 NRPMYDFEAVALQEN--ANLSIVTNATVHVVDVNDERGVL-----LKGAHSPI------I 685
Y F +A N LS + + V V+D ND L+ + I +
Sbjct: 1270 MIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYV 1329
Query: 686 FHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK-- 742
++ N+ G + Q+ + S NG G V + + Q DV +DG + T
Sbjct: 1330 AYLDVNAKVGTFVKQVMARD-SDFRENGNGLVIYSLTGQSDVLQFSIDPKDGVVTTASKF 1388
Query: 743 -PLDREKRDVY---RMTVIA-EFNKGVISGAGIYQV-----TIYIEDENDNPPVFEHATY 792
P + R Y +TV+A +F S + V T+ + PP+F + Y
Sbjct: 1389 TPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYY 1448
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGD 851
E + EN I ++ T + N F + + G+ + F +DE G + ++
Sbjct: 1449 EIELRENDP-APRI----VLNVTLSKRYANDPFRWEIVGDTFDDQFRIDERNGSL-WLLR 1502
Query: 852 SLDREKKIMY----KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
LDRE++ Y ++ + R+T + S ++ EN K + +++ +N + +
Sbjct: 1503 PLDREERDSYDVRIRVQKIKRETRNIPS-----VLYALENPVKRKSHRLFDNEVEIMIKV 1557
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLF-LIPENIPIGTTIIKLNALDLDSGLNGQI 966
+N A P + D GP+ ++P+ G ++K+ A D D+G NG++
Sbjct: 1558 VDVNDNA--------PVFR-----DNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEV 1604
Query: 967 RYEFNSEVYIPPSKLSADAL 986
RY +E PP + D+L
Sbjct: 1605 RYTLLNE---PPRLFAIDSL 1621
Score = 79.0 bits (186), Expect = 9e-13
Identities = 123/489 (25%), Positives = 204/489 (41%), Gaps = 73/489 (14%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK--VGTVIGKVKAVDPDLGQNGMVL 496
L + V+ + D NDN PVF Y F++ + G IG+V+A D D G NG V
Sbjct: 1180 LSDMLQVQFRVYDVNDNAPVF-EKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVT 1238
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
Y L + I PF I+P GT+ V+ E + V ASD N + + S A+
Sbjct: 1239 YMLITDGDQKI--PFSISPLDGTIRVSGEIDREMIASYRFRVLASD---NNFDLKLS-AM 1292
Query: 555 VTIEV-TRGTKGNKPDIPDF----------MGAP-YEFWVGSNVGIGTSVGQIRVNDA-F 601
V +EV N P+ + P Y ++ N +GT V Q+ D+ F
Sbjct: 1293 VDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKVGTFVKQVMARDSDF 1352
Query: 602 EQND---VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN---RPMYDFEAVALQENAN 655
+N V Y L G + + F+++ + GV+T + R Y+ V + + +
Sbjct: 1353 RENGNGLVIYSLT-GQSDVLQFSIDPKDGVVTTASKFTPSEAGTRKTYEHLNVTVVAS-D 1410
Query: 656 LSIVTNATVHVVDVNDERGVLLKGA--HSPIIF-------HVKENSAGAAIGQIFHTNMS 706
+++ ++ VN + L + P +F ++EN I + + +S
Sbjct: 1411 FGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYEIELRENDPAPRI--VLNVTLS 1468
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVY----RMTVIAEFN 761
Y N R+ I D I E +G+++ +PLDRE+RD Y R+ I
Sbjct: 1469 KRYANDP--FRWEIVGDT-FDDQFRIDERNGSLWLLRPLDREERDSYDVRIRVQKIKRET 1525
Query: 762 KGVISGA----------------GIYQVTIYIEDENDNPPVFE--HATYEGFIMENSKIG 803
+ + S ++ I + D NDN PVF + + + + G
Sbjct: 1526 RNIPSVLYALENPVKRKSHRLFDNEVEIMIKVVDVNDNAPVFRDNYGPIISVVPDTANYG 1585
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+ ++ATD D G+N YTL E +F +D TG ++ + +SL K+ ++
Sbjct: 1586 YAVMK---VEATDDDAGSNGEVRYTLLNEPPRLFAIDSLTGQIRLL-NSLASFKEKVFGF 1641
Query: 864 SLVARDTGG 872
+ A D G
Sbjct: 1642 DVKATDREG 1650
Score = 73.7 bits (173), Expect = 3e-11
Identities = 141/587 (24%), Positives = 243/587 (41%), Gaps = 79/587 (13%)
Query: 579 EFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDL-----LHGYEEGVPFAVEERSGVITV 631
+F + NV +G + ++ ND FE+N V Y++ L+ E F ++ +G + V
Sbjct: 1099 KFALPENVEVGKVIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRV 1158
Query: 632 VDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
+ L P D + + ++ LS + V DVND V K ++ F+V E
Sbjct: 1159 ANRLP----PETDVKLNITAKDVGGLSDMLQVQFRVYDVNDNAPVFEKQWYT---FNVDE 1211
Query: 691 NS---AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDR 746
S G IGQ+ N NG NV +++ D +I+ DGTI +DR
Sbjct: 1212 GSYPITGKKIGQV-RANDEDTGMNG--NVTYMLITDGDQKIPFSISPLDGTIRVSGEIDR 1268
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF--------------EHATY 792
E YR V+A N + + + V + + D NDN P F Y
Sbjct: 1269 EMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVY 1328
Query: 793 EGFIMENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGKEM-FDVDENTGVV--- 846
++ N+K+GT +K + A D+D E N L +Y+L G+ + F +D GVV
Sbjct: 1329 VAYLDVNAKVGTFVKQ---VMARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDGVVTTA 1385
Query: 847 -KFIGDSLDREKKIMY-KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
KF K + +++VA D G + ++++ + D + + +EE +
Sbjct: 1386 SKFTPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQ-HPVEERPPLFP 1444
Query: 905 HR----ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN-ALDLD 959
++ E + N A ++ V ++A D + ++ + I + N +L L
Sbjct: 1445 YKYYEIELRENDPAPRIVLNVTLSKRYANDPFRWE---IVGDTFDDQFRIDERNGSLWLL 1501
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN--ERHGHVIVARSLPPESEFRLNI 1017
L+ + R ++ + + K + Y + N +R H + ++E + I
Sbjct: 1502 RPLDREERDSYDVRIRVQKIKRETRNIPSVLYALENPVKRKSHRLF------DNEVEIMI 1555
Query: 1018 SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
+D +NDN V +D ++ P+ + A Y V+ KV+ATD D G N
Sbjct: 1556 KVVD---VNDNAPV---FRD--NYGPIISVV-----PDTANYGYAVM-KVEATDDDAGSN 1601
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+ Y + L F I LTG + + L E + V A D
Sbjct: 1602 GEVRYTLLNEPPRL-FAIDSLTGQIRLLNSLASFKEKVFGFDVKATD 1647
Score = 70.9 bits (166), Expect = 2e-10
Identities = 77/288 (26%), Positives = 129/288 (44%), Gaps = 17/288 (5%)
Query: 422 PDKVGT-KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
PD T + E + D +F V++ ++D NDN P F +LY S+ N G I
Sbjct: 317 PDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEF-EVDLYNISIIENLPKGFSIL 375
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEA 538
+V A+D D G+N Y L F I+ +G + V + L E R +L +
Sbjct: 376 QVNAIDRDQGENAEFYYYLMDEEP---KGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNV 432
Query: 539 -SDQPANPSERRYSLAVVTIEVT-RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
+ + +R + V +E+T T N P+ G YEF N IG+ VGQIR
Sbjct: 433 HAVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFE--QGTLYEFKTHCNASIGSKVGQIR 490
Query: 597 VNDAFE--QNDVSYDLLHGYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN 653
D + + Y + + +PF ++ +G I V + L+ Y + + EA +N
Sbjct: 491 ALDPDDLGNGKIQYSIKNVRPNLVIPFLLDPDTGDIRVSEALT-YGKIAFFVEARDQPQN 549
Query: 654 ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQI 700
+ S N + +D+ + ++ +P F V ++A G+++GQI
Sbjct: 550 PSESRF-NVALVTIDIVCQSIEDIEFIGAPYEFWVGADAAIGSSVGQI 596
Score = 68.9 bits (161), Expect = 1e-09
Identities = 115/430 (26%), Positives = 175/430 (40%), Gaps = 72/430 (16%)
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
EL SG F +D NG L + L + + L + L++ L+ V+
Sbjct: 1137 ELNSGERVSYFRIDRNNGELRVANRLPPETDVKLN----ITAKDVGGLSDMLQ-----VQ 1187
Query: 294 IELLDLNDNLPEFEVDFYNISIVE-NLP-NGFSVLQVMATDKDQGENGEFTYQL---DDP 348
+ D+NDN P FE +Y ++ E + P G + QV A D+D G NG TY L D
Sbjct: 1188 FRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQ 1247
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV-VGTFADSQRIAKWRRQP 407
K FSI P G T+R +DRE +S R +V A + N + + D + I R
Sbjct: 1248 KIPFSISPLDG--TIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRND- 1304
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
N P E T Y D + + NI+ + V V LD N FV
Sbjct: 1305 ---NNP-EFTAY---DDLRSDRNNIKR--------LPVYVAYLDVNAKVGTFVK------ 1343
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQ--NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE- 524
+V A D D + NG+V+Y L S++ F I+P G V+ A
Sbjct: 1344 -------------QVMARDSDFRENGNGLVIYSLTGQSDVL---QFSIDPKDGVVTTASK 1387
Query: 525 -SPILEGRHALF------VEASDQPANPSERRYSLAVVTIEVTRGTKGNKP---DIPDFM 574
+P G + V ASD P R S+A++ + + T P P F
Sbjct: 1388 FTPSEAGTRKTYEHLNVTVVASDFGTPP---RSSMALLIVNLQGDTLQQHPVEERPPLFP 1444
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDD 634
YE + N V + ++ + + ++++ G F ++ER+G + ++
Sbjct: 1445 YKYYEIELRENDPAPRIVLNVTLSKRYANDPFRWEIV-GDTFDDQFRIDERNGSLWLLRP 1503
Query: 635 LSRYNRPMYD 644
L R R YD
Sbjct: 1504 LDREERDSYD 1513
Score = 66.9 bits (156), Expect = 4e-09
Identities = 115/491 (23%), Positives = 206/491 (41%), Gaps = 65/491 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D G+ + Y LI+ D+K+ FS+ ++G++ + E+D + ++ +V
Sbjct: 1224 VRANDEDTGMNGNVTYMLITDGDQKIPFSISPLDGTIRVSGEIDRE-----MIASYRFRV 1278
Query: 277 QASQLNNPLK-TAQARVEIELLDLNDNLPEFEV------DFYNIS--------IVENLPN 321
AS N LK +A VE+ ++D NDN PEF D NI + N
Sbjct: 1279 LASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKV 1338
Query: 322 GFSVLQVMATDKDQGENGE--FTYQLDDPKGA--FSIDPRSGWLTVRNQTVLD----REA 373
G V QVMA D D ENG Y L FSIDP+ G +T ++ R+
Sbjct: 1339 GTFVKQVMARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDGVVTTASKFTPSEAGTRKT 1398
Query: 374 HSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIE 433
+ L + V A + + A I + L+ + P+E+ +FP K +
Sbjct: 1399 YEHLNVTVVASDFGTPPRSSMA--LLIVNLQGDTLQQH-PVEERPPLFPYKY--YEIELR 1453
Query: 434 YYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
D +NV ++ AND + + ++ + + + G+ + ++ +D + +
Sbjct: 1454 ENDPAPRIVLNVTLSKRYANDPFRWEIVGDTFDDQFRIDERNGS-LWLLRPLDREERDSY 1512
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
V +Q+ T P + E+P+ H LF + +
Sbjct: 1513 DVRIRVQKIKRETRNIP-------SVLYALENPVKRKSHRLF-----------DNEVEIM 1554
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
+ ++V N P D G P V G +V ++ +DA +V Y LL
Sbjct: 1555 IKVVDV----NDNAPVFRDNYG-PIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTLL 1609
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENAN--LSIVTNATVHVVD 668
+ E FA++ +G I +++ L+ + ++ F+ A +E A+ S + N V+V+
Sbjct: 1610 N--EPPRLFAIDSLTGQIRLLNSLASFKEKVFGFDVKATDREGADDGKSTIANVFVYVLH 1667
Query: 669 VNDERGVLLKG 679
+ E ++L G
Sbjct: 1668 AHQEVCLILAG 1678
Score = 64.9 bits (151), Expect = 2e-08
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH--NLQANTFVLQ 275
++AID+D G A Y L+ + F +D +G + + E LD E +L+ N ++
Sbjct: 377 VNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVE 436
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDKD 334
+ Q + + +VEI LLD NDN PEFE Y N G V Q+ A D D
Sbjct: 437 -RVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPD 495
Query: 335 QGENGEFTYQLDDPKG----AFSIDPRSGWLTV 363
NG+ Y + + + F +DP +G + V
Sbjct: 496 DLGNGKIQYSIKNVRPNLVIPFLLDPDTGDIRV 528
Score = 61.7 bits (143), Expect = 2e-07
Identities = 61/213 (28%), Positives = 94/213 (44%), Gaps = 24/213 (11%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG---AGIYQVTIYIEDENDNPPVFEHA 790
E G +F QK +D + + T + I+ + +V I + D NDN P FE
Sbjct: 299 ETGVLFLQKEIDLDSESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVD 358
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFI 849
Y I+EN G I + A D D+G NA F Y L E K F +D +G +
Sbjct: 359 LYNISIIENLPKGFSILQ---VNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVR 415
Query: 850 GDS-LDREKKIMYKLSLVA------RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ LD+E++ K+++ A D + ++ I + D NDN PEF Q
Sbjct: 416 DETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQ-----GT 470
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLG 935
+T N + G + +++ ALD D LG
Sbjct: 471 LYEFKTHCNASIGSKVGQIR-----ALDPDDLG 498
Score = 55.2 bits (127), Expect = 1e-05
Identities = 27/72 (37%), Positives = 38/72 (52%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVFGFXXXXXXXXXX 1499
+ATD D G N ++RY +LNE FAID ++G +R++ +LA +VFGF
Sbjct: 1592 EATDDDAGSNGEVRYTLLNEPPRLFAIDSLTGQIRLLNSLASFKEKVFGFDVKATDREGA 1651
Query: 1500 XXXXXXXXNVFV 1511
NVFV
Sbjct: 1652 DDGKSTIANVFV 1663
Score = 51.2 bits (117), Expect = 2e-04
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 29/198 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+P G +I+++NA+D D G N + Y E E K F+I+ G
Sbjct: 364 IIENLPKGFSILQVNAIDRDQGENAEFYYYLMDE-------------EPKGAFMIDHGSG 410
Query: 1000 HVIVARS--LPPE--SEFRLNISALDGGNLND------NISVRVFVKDVNDHFPVFKK-T 1048
++V L E S ++N+ A++ D + V + + D ND+ P F++ T
Sbjct: 411 WIVVRDETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGT 470
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL--PFEISPLTGVLSVNG 1106
Y F +G++ A D D N + Y I+ +L PF + P TG + V+
Sbjct: 471 LYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSIKNVRPNLVIPFLLDPDTGDIRVSE 530
Query: 1107 ELDRETEDKYILTVVARD 1124
L T K V ARD
Sbjct: 531 AL---TYGKIAFFVEARD 545
Score = 46.8 bits (106), Expect = 0.005
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Query: 1009 PESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
P++ F L I A + + RV ++ D+ND+ P F+ YN ++ E + +
Sbjct: 317 PDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFSILQ 376
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE--LDRETEDKYILTV--VA 1122
V+A D D G+NA Y++ + F I +G + V E LD+E + V V
Sbjct: 377 VNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVE 436
Query: 1123 R-DNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
R + D NDN+P+F
Sbjct: 437 RVEQYDRSRNYGKVQVEITLLDTNDNTPEF 466
Score = 45.2 bits (102), Expect = 0.014
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 15/155 (9%)
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
SL L++ LD DA + +Q+ AS NP +TA A + + L D++D P F Y
Sbjct: 189 SLVLQRALDYDAGWRSMS----VQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQY 244
Query: 312 NISIVENLP-NG-------FSVLQVMATDKDQ-GENGEFTYQLDDPKGAFSIDPRSGWLT 362
I E+ P G + +MA D+D E + + + F I P +G L
Sbjct: 245 RTRIKESFPLTGKPIHIPLYIEPPIMAFDQDSLNETLVYGIVAGNERQLFWISPETGVLF 304
Query: 363 VRNQTVLDREA--HSSLRMKVYAKETNPSVVGTFA 395
++ + LD E+ ++ +++ A++ N FA
Sbjct: 305 LQKEIDLDSESLPDNTFTLQIEAQQINDPTKSAFA 339
Score = 41.5 bits (93), Expect = 0.17
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 17/167 (10%)
Query: 1001 VIVARSLPPESEFR---LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ R+L ++ +R + I A D GN N ++RV ++DV+D P+F + Y ++
Sbjct: 190 LVLQRALDYDAGWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIK 249
Query: 1056 EA--------QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
E+ + + A D D N L Y I + F ISP TGVL + E
Sbjct: 250 ESFPLTGKPIHIPLYIEPPIMAFDQD-SLNETLVYGIVAGNERQLFWISPETGVLFLQKE 308
Query: 1108 LDRETE---DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+D ++E D + D+NDN P+F
Sbjct: 309 IDLDSESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEF 355
Score = 41.5 bits (93), Expect = 0.17
Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 12/132 (9%)
Query: 773 VTIYIEDENDNPPVFEHATY-----EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+ + + D +D PP+F A Y E F + I + ++ I A D D L
Sbjct: 225 IRVNLRDVDDLPPIFTRAQYRTRIKESFPLTGKPIHIPLYIEPPIMAFDQDSLNETLVYG 284
Query: 828 TLFGEGKEMFDVDENTGVVKFIGDSLDREKKIM----YKLSLVARDTGG--LSSEAELII 881
+ G +++F + TGV+ F+ +D + + + + L + A+ S+ A + I
Sbjct: 285 IVAGNERQLFWISPETGVL-FLQKEIDLDSESLPDNTFTLQIEAQQINDPTKSAFARVDI 343
Query: 882 MIGDENDNKPEF 893
+ D NDN PEF
Sbjct: 344 EVIDLNDNVPEF 355
Score = 37.1 bits (82), Expect = 3.7
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 846 VKFIG-DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
+ F+G + LDRE+ L ++A D L SE EL I+I D ND P F +I
Sbjct: 959 ILFMGPNKLDREEIESLTLKMMATDRDNLMSEVELKILILDVNDCAPVFERI 1010
Score = 37.1 bits (82), Expect = 3.7
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 22/131 (16%)
Query: 1255 PVFISRYYELEIEEN----VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
PVF ++Y ++E + V N + N + Y ++ + D I F I P
Sbjct: 1198 PVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKI--PFSISP 1255
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRI 1370
+GT+ + DRE+ +Y V A + +L M+ DV+V+V
Sbjct: 1256 LDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMV--------------DVEVIV-- 1299
Query: 1371 KDVNDNSPKFT 1381
D NDN+P+FT
Sbjct: 1300 MDRNDNNPEFT 1310
Score = 36.7 bits (81), Expect = 4.9
Identities = 41/161 (25%), Positives = 74/161 (45%), Gaps = 21/161 (13%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
Q + P+ S+ A + + V D+ D V P F Y + I EN+ ++ +N +
Sbjct: 328 QQINDPTKSAFARVDIEVIDLNDNV-----PEFEVDLYNISIIENLPKGFSILQVNAIDR 382
Query: 1285 Y--ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
EN + YY+++E + F+ID +G+ ++V V+D E + E++ +
Sbjct: 383 DQGENAEFYYYLMDEEP---KGAFMID--HGSGWIV------VRD--ETFLDKEQRSSLK 429
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
H + V E V+V + + D NDN+P+F G
Sbjct: 430 MNVHAVERV-EQYDRSRNYGKVQVEITLLDTNDNTPEFEQG 469
>UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n=1;
Danio rerio|Rep: UPI00015A700B UniRef100 entry - Danio
rerio
Length = 3528
Score = 211 bits (516), Expect = 1e-52
Identities = 212/799 (26%), Positives = 355/799 (44%), Gaps = 84/799 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S+ V + + D NDN PV + +L + +A GT +G + D D NG V
Sbjct: 128 LTSYSMVIIDVTDTNDNAPVIISKSL-NIPIPESALPGTEVGIINVQDRDSENNGQVRCS 186
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+Q+ + K + T + +L + + + A+D+ + P ++ + +
Sbjct: 187 IQQNVPFKLVPSIKNYYSLVTTGELDRELLS-EYNITITATDEGSPPLSSTKNIHLTVAD 245
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN-DVSYDLLHGYEE 616
V + P P F A Y+ + N + T V + DA E QN +V+Y+ H E
Sbjct: 246 VN-----DNP--PVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHISEN 298
Query: 617 GVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV--HVVDVNDER 673
+ F++++ SG IT++ L + +D + +Q L +V+ +TV V DVND
Sbjct: 299 DITIFSLDQNSGKITLIGSLDYEDEASFD---LPIQATDGLGLVSYSTVVIDVSDVNDNP 355
Query: 674 GVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIA--NQQDVTDDI 730
V + + HV+EN+ AG++I + T+ NGT L + N V+ +
Sbjct: 356 PVFQQQNYRA---HVQENNKAGSSISSVSATD-PDWRQNGTVVYSLLSSDVNGAPVSSFL 411
Query: 731 AIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+I D G I + D E+ +++ V+A N + + + + + D NDN PVF
Sbjct: 412 SINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNV-SIHVTVLDANDNAPVFSQ 470
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT---LFGEGKEMFDVDENTGVV 846
A Y+ + ENS + T + + ATDADEG N Y + + K +F++D TGV+
Sbjct: 471 AVYKVSLPENSPVDTVVV---TVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKTGVI 527
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEE-------- 898
G +D E++ + L ++A+D GL+S + ++I + D NDN P + E
Sbjct: 528 SIKG-PVDFEEEATFSLRIIAKDGSGLTSYSNVLISVSDVNDNSPIIIPLTETPGSFMPS 586
Query: 899 ----NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
S+ + RE+K + + ++ ++ + L +NIP+G+ ++KLN
Sbjct: 587 GRLITSRKPLDRESKADHFLTLSGVDGGRPSRSGTASIHIHVLD-ANDNIPVGSVLVKLN 645
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
A DLDSG+ G + Y F+ ++P + LEV + G V + + +
Sbjct: 646 ATDLDSGIYGAVSYSFS---HVPDK--TRGILEV------DSVTGEVRIMLDREKCTHYN 694
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
+ I+A+D G L + +V + V D+ND+ P+F+ Y E Q + K+ A DA
Sbjct: 695 ITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPRGTPVIKIKADDA 754
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
D GQNA + Y + D+ + I+ TG + D E + +ARD G
Sbjct: 755 DGGQNARILYSLS-EDSAIYLSINTETGEIFTIRPFDYEASTHFYAQAMARDGG-RPSFT 812
Query: 1133 XXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI 1192
D+NDN P +P VYK + ENA
Sbjct: 813 STCTIRIYITDMNDNPPVVL---------YP--------------YYTVYKTNVAENAVK 849
Query: 1193 GTTVAKVFANDTDFIGNGN 1211
GT + KV A D D N N
Sbjct: 850 GTIITKVSAFDADQGYNSN 868
Score = 198 bits (482), Expect = 1e-48
Identities = 202/725 (27%), Positives = 313/725 (43%), Gaps = 75/725 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V ++VT+LDANDN PVF +Y S+ NA GT I V A D D G G + Y+ +
Sbjct: 1247 VIIDVTVLDANDNAPVF-NQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQ 1305
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVT 560
F I+ NTG +SV E + L VEA DQ + +L V+ +
Sbjct: 1306 KGAA-AQLFNIDSNTGIISVVGEIDHEKDTKFELTVEARDQGGLTDSSKITLDVIDVN-- 1362
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVP 619
+ P + V + T++ I V DA + N + G E+ V
Sbjct: 1363 -------DNAPVINAMSFSSTVSEDAPPDTTIAIINVKDADTDDNGRVSCFIEGSEDFVV 1415
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
+ + L R Y+ VA L+ + VVDVND V +
Sbjct: 1416 KSTLRNYYSLVTNVILDREKLSEYNITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRE 1475
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGT 737
++ + + NS G +I +I + N + +++ + D+ +++ AE G
Sbjct: 1476 RVYNSYL--PENNSPGVSILRIRAHDPDE---NQNARISYIL-EESDLGTYVSVNAESGV 1529
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ + D E+ ++TV A+ + + + + + D NDN PVF Y +
Sbjct: 1530 VHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNV-TIDVTVLDVNDNAPVFNQTVYRASVT 1588
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNA---LFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
EN+ GT I + ATDAD G+N L L + + +F++DENTG+V +G ++D
Sbjct: 1589 ENAPKGTYI---TTVNATDADSGSNGHITLSFSDLKEQSRGIFNIDENTGLVSVLG-NID 1644
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
EK +++ + A D GGL+S ++LII + D NDN P + +S V +
Sbjct: 1645 FEKDKRFEIRVKATDQGGLTSTSKLIIEVVDVNDNAPVITLMSLSSPV------SEDAPP 1698
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
G TI LI N P G +I + A DLD N ++ Y
Sbjct: 1699 GTTI------------------AVLIENNTP-GLSICSVTARDLDWNQNSRVSY------ 1733
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDN-- 1028
Y+ + +S + + Y IN +G + RS E +F + A DGG+ L+ N
Sbjct: 1734 YLEDAHIS--GVPISSYVSINAENGVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKF 1791
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I + + V D ND+ PVF ++ Y V E ++ V ATDAD G N+ + Y I +
Sbjct: 1792 IDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANME 1851
Query: 1089 TDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
D+ F I+ G +SV G +D E Y + V A D G D ND
Sbjct: 1852 DDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQG----GLTDSYINIIVLDAND 1907
Query: 1147 NSPKF 1151
N+P F
Sbjct: 1908 NAPVF 1912
Score = 188 bits (459), Expect = 8e-46
Identities = 251/1020 (24%), Positives = 427/1020 (41%), Gaps = 124/1020 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S N+ +T+ D NDN PVF + +Y+ S+ N+ V TV+ V A D D GQNG V Y+
Sbjct: 233 LSSTKNIHLTVADVNDNPPVFQQA-VYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYE 291
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEAS-DQPANPSERRYSLAVVTI 557
S IT F ++ N+G +++ S E EAS D P ++ ++ T+
Sbjct: 292 FGHISENDITI-FSLDQNSGKITLIGSLDYED------EASFDLPIQATDGLGLVSYSTV 344
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDLLHGYE 615
+ + P P F Y V N G+S+ + D + QN V Y LL
Sbjct: 345 VIDVSDVNDNP--PVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDV 402
Query: 616 EGVP----FAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHV--VD 668
G P ++ +GVI V Y + M F+ + L ++N + + +N ++HV +D
Sbjct: 403 NGAPVSSFLSINGDTGVIHAVRSFD-YEQ-MKSFKVLVLARDNGSPPLSSNVSIHVTVLD 460
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVT 727
ND V + + + ENS + + + + G V + + +D
Sbjct: 461 ANDNAPVFSQAVYK---VSLPENSPVDTV--VVTVSATDADEGQNGEVTYEFGHIMEDYK 515
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+ + G I + P+D E+ + + +IA+ G+ S + V I + D NDN P+
Sbjct: 516 HLFNLDRKTGVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSN---VLISVSDVNDNSPI 572
Query: 787 FEHATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
T G M + ++ T K D + A TL G +
Sbjct: 573 IIPLTETPGSFMPSGRLITSRK--------PLDRESKADHFLTLSGVDGGRPSRSGTASI 624
Query: 846 VKFIGDSLDREK--KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+ D+ D ++ KL+ D+G + + + D+ E + + ++
Sbjct: 625 HIHVLDANDNIPVGSVLVKLNATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRIM 684
Query: 904 IHRETKLNGTAGFTIIEVKPKNKFA--------LDVDQLGPLFL-------IPENIPIGT 948
+ RE + T ++ F+ D++ P+F EN P GT
Sbjct: 685 LDREKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPRGT 744
Query: 949 TIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP 1008
+IK+ A D D G N +I Y + + I Y IN G + R
Sbjct: 745 PVIKIKADDADGGQNARILYSLSEDSAI--------------YLSINTETGEIFTIRPFD 790
Query: 1009 PESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF---NVEEAQYTR 1061
E+ F A DGG + ++R+++ D+ND+ PV +Y NV E
Sbjct: 791 YEASTHFYAQAMARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKG 850
Query: 1062 RVLGKVDATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++ KV A DAD G N+N+TY DT F+IS TG +++ G LD ET +Y L
Sbjct: 851 TIITKVSAFDADQGYNSNVTYSFTHIAEDTAHLFQISASTGDITLTGNLDYETVQQYELN 910
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSP--KFYAFDELLEWKHPEADE---LSNHNFE 1174
+ A+D DVNDNSP +F ++ P +S + +
Sbjct: 911 LQAKD---PWGLTGASKLVIDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLD 967
Query: 1175 SVMMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
S V + +E+++P I + K + TD + + ++L + G PSL
Sbjct: 968 SGKNGQV-RLALEQSSPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDE--GSPSL 1024
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKM 1290
S + + V D+ D + PVF R Y+ + EN + V L++L + + +N ++
Sbjct: 1025 FSKITISLDVTDIND-----NAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARI 1079
Query: 1291 RYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
YY+++ N + + F ++ NG ++ VRS D E +++ VRA+ P
Sbjct: 1080 AYYLIDSDVNGSPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQ----DGGSP--- 1132
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK----FTNGNRPLVTAIPTTAPFGYQVMQL 1404
P+ + VV+ ++D NDN+P+ +G + +P +A GY V ++
Sbjct: 1133 -PLCS---------NATVVINVQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKV 1182
Score = 163 bits (396), Expect = 3e-38
Identities = 218/815 (26%), Positives = 331/815 (40%), Gaps = 110/815 (13%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + VT+LDANDN PVF + +Y+ S+ N+ V TV+ V A D D GQNG V Y
Sbjct: 27 VAIHVTVLDANDNAPVFSQA-VYKVSLPENSPVDTVVVTVSATDADEGQNGKVTYVFGHV 85
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S T F +N NTG ++V + E + A + A + S ++V I+VT
Sbjct: 86 SEEDKTL-FSLNRNTGEITVTGAIDYEEKSAYELRVL---AKDAAGLTSYSMVIIDVT-D 140
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF-- 620
T N P I + + + GT VG I V D +N + + ++ VPF
Sbjct: 141 TNDNAPVI---ISKSLNIPIPESALPGTEVGIINVQDRDSEN--NGQVRCSIQQNVPFKL 195
Query: 621 --AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
+++ ++T +L R Y+ A E + LS N + V DVND V
Sbjct: 196 VPSIKNYYSLVT-TGELDRELLSEYNITITATDEGSPPLSSTKNIHLTVADVNDNPPVFQ 254
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ + + ENS + + NG F ++ D+T G
Sbjct: 255 QAVYK---VSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHISENDITIFSLDQNSGK 311
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I LD E + + + A G++S + V I + D NDNPPVF+ Y +
Sbjct: 312 ITLIGSLDYEDEASFDLPIQATDGLGLVSYS---TVVIDVSDVNDNPPVFQQQNYRAHVQ 368
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENTGVVKFIGD 851
EN+K G+ I + + ATD D N +Y+L ++ +TGV+ +
Sbjct: 369 ENNKAGSSI---SSVSATDPDWRQNGTVVYSLLSSDVNGAPVSSFLSINGDTGVIHAV-R 424
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ------IEENSKV- 902
S D E+ +K+ ++ARD G LSS + + + D NDN P F+Q + ENS V
Sbjct: 425 SFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDNAPVFSQAVYKVSLPENSPVD 484
Query: 903 -------RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI---GTTIIK 952
+ NG + + K ++D+ + I + T ++
Sbjct: 485 TVVVTVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKTGVISIKGPVDFEEEATFSLR 544
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS-LPPES 1011
+ A D SGL + S + E F+ + G +I +R L ES
Sbjct: 545 IIAKD-GSGLTSYSNVLISVSDVNDNSPIIIPLTETPGSFMPS---GRLITSRKPLDRES 600
Query: 1012 --EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ L +S +DGG + + S+ + V D ND+ PV VL K+
Sbjct: 601 KADHFLTLSGVDGGRPSRSGTASIHIHVLDANDNIPV----------------GSVLVKL 644
Query: 1068 DATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ATD D G ++Y P T E+ +TG + + LDRE Y +T+ A D
Sbjct: 645 NATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRI--MLDREKCTHYNITITAVDA 702
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
G D+NDN P F +H Y
Sbjct: 703 G-TPPLFSSKTVAITVTDINDNPPIF---------RHAN-----------------YTVQ 735
Query: 1186 IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
EN P GT V K+ A+D D G N ILYSL +
Sbjct: 736 FAENQPRGTPVIKIKADDAD--GGQNARILYSLSE 768
Score = 157 bits (380), Expect = 3e-36
Identities = 182/725 (25%), Positives = 310/725 (42%), Gaps = 78/725 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMK-SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V + + + D NDN PVF S+ Y+ S++ NA G V+ +V A D D G NG + Y R
Sbjct: 2755 VTLSLQISDVNDNAPVFEQSS-YQASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSR 2813
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEV 559
+S + F I P+TG ++V E + L ++A+D+ + V I++
Sbjct: 2814 SSGKNLDL-FHIGPDTGEITVKGHLDYERAKQFELNIDATDKGGLTDSSK-----VIIDI 2867
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T + P + + + + + T + + V D + + +P
Sbjct: 2868 T--DVNDNPPVISLIS--FSNPIPEDAAPETVIAMLNVKDLDSGKNGQVKCYISAD--MP 2921
Query: 620 FAVEERS-GVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGV 675
F V+ + +++ D L R Y+ A E + + S T+ + DVND V
Sbjct: 2922 FKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPV 2981
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL-IANQQDVTDDIAIAE 734
+ +++ I ++ NS G ++ + + S GN FL ++ + D E
Sbjct: 2982 FERQSYTAFI--IENNSPGVSVLSVKAHDRDS--GNNARISYFLDLSGSEHGNDGSKYVE 3037
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+ Q PLDRE + +++T+ A F+ G G ++ + + D NDN PVF Y
Sbjct: 3038 ---MVLQAPLDRETQHEHKLTLTA-FDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRV 3093
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ EN+ G + + ATD D+G N G+ + ++G +LD
Sbjct: 3094 SLFENAPNGAVVVR---VSATDNDQGAN----------GEITYSFSRSSG------KNLD 3134
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
L + DTG +++ LI D+ ++ + + E N V E + +
Sbjct: 3135 --------LFHIGADTGEITNFYSLIT---DQLLDREKIS--EYNITVTATDEGSPSFST 3181
Query: 915 GFTI-IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
T+ +++ N A ++ I EN G +++ + A D DSG N +I Y F +
Sbjct: 3182 NKTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLSVKAHDRDSGNNARISY-FLED 3240
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISV 1031
V + + + + +N G ++ ARS E +F + + A DGG+ + ++
Sbjct: 3241 VVV-------NGVSASTFISVNAESGEILAARSFDYEQTKDFSIRVKAQDGGSPPLSSNI 3293
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
V V D ND+ P F ++ Y ++ E + KV A D D G N +TY + S
Sbjct: 3294 NVIVLDANDNAPAFSQSVYKASIPENFSKGSSVLKVSAADGDTGSNGEVTYSLSQSSESF 3353
Query: 1092 P--FEISPLTGVLSVN---GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
F I TG ++VN LDRE +Y +TV A D G DVND
Sbjct: 3354 SGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVTATDEG-SPSFSTNKTLTLKISDVND 3412
Query: 1147 NSPKF 1151
N+P F
Sbjct: 3413 NAPVF 3417
Score = 151 bits (365), Expect = 2e-34
Identities = 212/864 (24%), Positives = 355/864 (41%), Gaps = 89/864 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK----------------- 115
GL +S Y +V + + DVNDN P+F Y V E G
Sbjct: 335 GLGLVS-YSTVVIDVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTV 393
Query: 116 AFIFLIAPI-GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
+ L + + G ++ L++ + +R+FD ++ + +V D+G L
Sbjct: 394 VYSLLSSDVNGAPVSSFLSINGDTGVIHAVRSFDYEQMKS-----FKVLVLARDNGSPPL 448
Query: 175 ESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
S+ V + VLD + F Q V S + A D D G + Y
Sbjct: 449 SSN---VSIHVTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTY 505
Query: 234 EL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
E I + + LF+LD G + ++ +D + E TF L++ A + T+ +
Sbjct: 506 EFGHIMEDYKHLFNLDRKTGVISIKGPVDFEEEA-----TFSLRIIAKDGSG--LTSYSN 558
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK---DQGENGEFTYQLDDP 348
V I + D+NDN P I + E P F + T + D+ + L
Sbjct: 559 VLISVSDVNDNSPII------IPLTET-PGSFMPSGRLITSRKPLDRESKADHFLTLSGV 611
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAH---SSLRMKVYAKETNPSVVGTFADS-QRIAKWR 404
G RSG ++ VLD + S+ +K+ A + + + G + S +
Sbjct: 612 DGGRP--SRSGTASIHIH-VLDANDNIPVGSVLVKLNATDLDSGIYGAVSYSFSHVPDKT 668
Query: 405 RQPLETNAPLEKTTYVFP-DKVGTKTENIEYYDE---QLMSFVNVEVTLLDANDNNPVFV 460
R LE ++ + + +K I D L S V +T+ D NDN P+F
Sbjct: 669 RGILEVDSVTGEVRIMLDREKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFR 728
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV 520
+N Y N GT + K+KA D D GQN +LY L S + ++ IN TG +
Sbjct: 729 HAN-YTVQFAENQPRGTPVIKIKADDADGGQNARILYSLSEDSAIYLS----INTETGEI 783
Query: 521 SVAESPILEGRHALFVEA-SDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE 579
E + +A + PS S + I +T N P + Y+
Sbjct: 784 FTIRPFDYEASTHFYAQAMARDGGRPSFT--STCTIRIYIT-DMNDNPPVVLYPYYTVYK 840
Query: 580 FWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVP-FAVEERSGVITVVDDLS 636
V N GT + ++ DA + ++V+Y H E+ F + +G IT+ +L
Sbjct: 841 TNVAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIAEDTAHLFQISASTGDITLTGNLD 900
Query: 637 RYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
Y+ A ++ L+ + + VVDVND V+ + S I +++ AG
Sbjct: 901 YETVQQYELNLQA-KDPWGLTGASKLVIDVVDVNDNSPVISMTSFSGKI--QEDSPAGTV 957
Query: 697 IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV 756
+ I ++ + G VR + T + + T+ T PLDREK + +T+
Sbjct: 958 VALI---SVQDLDSGKNGQVRLALEQSSPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTL 1014
Query: 757 IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATD 816
+A ++G S +++ + D NDN PVF Y+ ++MEN+ G + ++A+D
Sbjct: 1015 VAT-DEGSPSLFSKITISLDVTDINDNAPVFSQREYKAYVMENNSPGVSLL---TLQASD 1070
Query: 817 ADEGTNALFMYTLFGEG------KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
D G NA Y L F V+ + G++ + S D E+ +K+ + A+D
Sbjct: 1071 PDAGQNARIAYYLIDSDVNGSPVSSHFSVNADNGIIHAV-RSFDYEQMKEFKIHVRAQDG 1129
Query: 871 GG--LSSEAELIIMIGDENDNKPE 892
G L S A ++I + D+NDN P+
Sbjct: 1130 GSPPLCSNATVVINVQDQNDNAPQ 1153
Score = 142 bits (345), Expect = 5e-32
Identities = 179/723 (24%), Positives = 307/723 (42%), Gaps = 65/723 (8%)
Query: 202 MASGKRI-HKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD 260
+ G R+ HK IL+ I D L A + ++ ND N +F +K
Sbjct: 2400 LGKGHRVDHKNILYKNAIDGGDPQLSGTAQIHITVLDAND---------NAPVFTQKIYK 2450
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE-FEVDFYN-----IS 314
N T + V AS L+ + + ++ + + D++P FE++ N I
Sbjct: 2451 ASITENAVRGTVITTVSASDLD---EGSYGKITYAITNTLDDVPVLFEINETNGEVRVIG 2507
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT--VRNQTVLDRE 372
V+ + V A+D D G +D + + T + ++ +
Sbjct: 2508 TVDYEKARHYQIHVQASD-DGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITENA 2566
Query: 373 AHSSLRMKVYAKETNPSVVG--TFADSQRIAKWRR--QPLETNAPLEKTTYVFPDKVGTK 428
++ V A + + G T+A + + + + ETN ++ +K+ T
Sbjct: 2567 VRGTIITTVTASDLDEGSYGKITYAITNSLGNFPMLFEINETNGEIQTR-----EKMITL 2621
Query: 429 TENIEYY--------DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
+E+Y D QL + + +T+ DANDN P+ S +Y+ S+ N+ GTV+
Sbjct: 2622 ENPMEFYSITAVDGGDPQLSGTIPIIITVEDANDNAPICFMS-VYKTSVAENSPKGTVLT 2680
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEA 538
VKA D D GQNG V Y + +++ TI + F+I+ N G + ++ E + + V+A
Sbjct: 2681 TVKASDADQGQNGKVEYHIAKSTGGTI-NLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQA 2739
Query: 539 SDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVG-SNVGIGTSVGQIRV 597
D P S+ S+ VT+ + + + P F + Y+ V N G V ++
Sbjct: 2740 RD-PGRHSDTCKSINSVTLSLQISDVND--NAPVFEQSSYQASVQFENAPNGAVVVRVSA 2796
Query: 598 --NDAFEQNDVSYDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA 654
ND +++Y + + F + +G ITV L ++ + +
Sbjct: 2797 TDNDQGANGEITYSFSRSSGKNLDLFHIGPDTGEITVKGHLDYERAKQFELN-IDATDKG 2855
Query: 655 NLSIVTNATVHVVDVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
L+ + + + DVND V+ L +PI E++A + I N+ +
Sbjct: 2856 GLTDSSKVIIDITDVNDNPPVISLISFSNPI----PEDAAPETV--IAMLNVKDLDSGKN 2909
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
G V+ I+ + ++ T + LDREK Y +TV A ++G S + +
Sbjct: 2910 GQVKCYISADMPFKVKSSAQNFYSLITDQLLDREKISEYNITVTAT-DEGSPSFSTNKTL 2968
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
T+ I D NDN PVFE +Y FI+EN+ G + +KA D D G NA Y L G
Sbjct: 2969 TLKISDVNDNAPVFERQSYTAFIIENNSPGVSVLS---VKAHDRDSGNNARISYFLDLSG 3025
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
E + D + V + LDRE + +KL+L A D G + + + + D NDN P
Sbjct: 3026 SEHGN-DGSKYVEMVLQAPLDRETQHEHKLTLTAFDGGNPQRTGTVRICVTVIDANDNAP 3084
Query: 892 EFN 894
F+
Sbjct: 3085 VFS 3087
Score = 138 bits (334), Expect = 1e-30
Identities = 125/471 (26%), Positives = 219/471 (46%), Gaps = 35/471 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ ++D NDN+PV + + ++ ++ GTV+ + D D G+NG V L+++S T
Sbjct: 927 IDVVDVNDNSPV-ISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSSPFT 985
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
I K +P V ++P+ + + F S +S ++++VT
Sbjct: 986 I----KPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLFSKITISLDVT----DI 1037
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP----F 620
+ P F Y+ +V N G S+ ++ +D A + ++Y L+ G P F
Sbjct: 1038 NDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLIDSDVNGSPVSSHF 1097
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATV--HVVDVNDERGVLL 677
+V +G+I V Y + M +F+ V Q+ + + +NATV +V D ND +L
Sbjct: 1098 SVNADNGIIHAVRSFD-YEQ-MKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDNAPQVL 1155
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---AE 734
S + A +G + T + ++ + +G +L TD A+
Sbjct: 1156 YPVQSGASVVAEIVPRSADVGYLV-TKVVAVDVD-SGQNAWLSYKLHKATDRALFEVGAQ 1213
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+G I T + + D ++ + N SG+ I VT+ D NDN PVF Y
Sbjct: 1214 NGEIRTVRQESADDHDSLKLIAVDGGNPQR-SGSVIIDVTVL--DANDNAPVFNQTVYRA 1270
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGVVKFIGD 851
+MEN+ GT I + ATDAD G+ Y + G ++F++D NTG++ +G+
Sbjct: 1271 SVMENAPKGTYI---TTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNTGIISVVGE 1327
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+D EK ++L++ ARD GGL+ +++ + + D NDN P N + +S V
Sbjct: 1328 -IDHEKDTKFELTVEARDQGGLTDSSKITLDVIDVNDNAPVINAMSFSSTV 1377
Score = 134 bits (324), Expect = 2e-29
Identities = 198/815 (24%), Positives = 326/815 (40%), Gaps = 126/815 (15%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + ++D NDN PVF +Y + N G I +++A DPD QN + Y
Sbjct: 1453 LTSRKTFNLKVVDVNDNAPVF-RERVYNSYLPENNSPGVSILRIRAHDPDENQNARISYI 1511
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
L+ + T S +N +G V S E + V+A D + P ++ V
Sbjct: 1512 LEESDLGTYVS---VNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVTV 1568
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYDLLH 612
++V + P F Y V N GT + + DA ++ +S+ L
Sbjct: 1569 LDVN-------DNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFSDLK 1621
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G+ F ++E +G+++V+ ++ ++ A + L+ + + VVDVND
Sbjct: 1622 EQSRGI-FNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGG-LTSTSKLIIEVVDVNDN 1679
Query: 673 RGVL-LKGAHSP----------IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
V+ L SP I ++ N+ G +I + ++ N V + +
Sbjct: 1680 APVITLMSLSSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDLD---WNQNSRVSYYLE 1736
Query: 722 NQQ----DVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTI 775
+ ++ ++I AE+G + + D E+ + V A+ +S + I
Sbjct: 1737 DAHISGVPISSYVSINAENGVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHI 1796
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ D NDN PVF M ++ KAT + + T+
Sbjct: 1797 TVLDANDNAPVF--------------------MQSVYKATVTENAPKDTIVSTVSAT--- 1833
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
D DE G+ I S+ + + +L + RD G +S ++ I D F +
Sbjct: 1834 --DADE--GINSKIEYSIANMEDDVQRLFAINRDNGQVS-----VVGIID-------FER 1877
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
N ++R+ + T + I V N A Q + EN P GT + ++A
Sbjct: 1878 AR-NYEIRVQASDQGGLTDSYINIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSA 1936
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EF 1013
DLD G+NG+I Y + + +V+ F I+E G V + + E F
Sbjct: 1937 SDLDQGVNGEITYSIRNTID-----------KVRDIFEISETDGKVRLIGLVDYEQARNF 1985
Query: 1014 RLNISALDGGNLNDNISVRVFV---KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ + A D G D+ + V V DVND+ PVF+++ Y +V+ + ++ KV A
Sbjct: 1986 EIRVQASDHGGFTDSCKIIVDVIDISDVNDNAPVFEQSSYQASVQRSADVGYLVTKVVAV 2045
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV--NGELDRETEDKYILTVVARDNGXX 1128
D D GQNA L+Y + + FE+ G + LDRE +++ L + A D G
Sbjct: 2046 DVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGG-D 2104
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
D NDN+P F M VYKAT+ E
Sbjct: 2105 PQLSGSIDIHITVLDANDNAPVF--------------------------MQSVYKATVTE 2138
Query: 1189 NAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN 1223
NAP T V+ V A D D N I YS+ R++
Sbjct: 2139 NAPKDTIVSTVSATDAD--EGINSKIEYSIANRQD 2171
Score = 130 bits (314), Expect = 3e-28
Identities = 130/483 (26%), Positives = 210/483 (43%), Gaps = 33/483 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D QL + +T+LDANDN PVF +Y+ S+ NA GTVI V A D D G G +
Sbjct: 2421 DPQLSGTAQIHITVLDANDNAPVFT-QKIYKASITENAVRGTVITTVSASDLDEGSYGKI 2479
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE-GRH-ALFVEASDQPANPSERRYSLA 553
Y + T + + F+IN G V V + E RH + V+ASD +
Sbjct: 2480 TYAITNTLD-DVPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDDGGLTDSCKID-- 2536
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLL 611
V I +T + P F Y+ + N GT + + +D E + ++Y +
Sbjct: 2537 -VDIHIT--VLDANDNAPVFTHKIYKASITENAVRGTIITTVTASDLDEGSYGKITYAIT 2593
Query: 612 HGYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDV 669
+ + F + E +G I + + PM + A+ + LS + V D
Sbjct: 2594 NSLGNFPMLFEINETNGEIQTREKMITLENPMEFYSITAVDGGDPQLSGTIPIIITVEDA 2653
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTD 728
ND + + V ENS G + T +S G G V + IA T
Sbjct: 2654 NDNAPICFMSVYKT---SVAENSPK---GTVLTTVKASDADQGQNGKVEYHIAKSTGGTI 2707
Query: 729 DIAIAED--GTIFTQKPLDREKRDVYRMTVIAEF---NKGVISGAGIYQVTIYIEDENDN 783
++ + G + +D EK Y++ V A + +++ I D NDN
Sbjct: 2708 NLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDVNDN 2767
Query: 784 PPVFEHATYEGFIM-ENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDV 839
PVFE ++Y+ + EN+ G + + ATD D+G N Y+ G+ ++F +
Sbjct: 2768 APVFEQSSYQASVQFENAPNGAVVVR---VSATDNDQGANGEITYSFSRSSGKNLDLFHI 2824
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
+TG + G LD E+ ++L++ A D GGL+ +++II I D NDN P + I +
Sbjct: 2825 GPDTGEITVKGH-LDYERAKQFELNIDATDKGGLTDSSKVIIDITDVNDNPPVISLISFS 2883
Query: 900 SKV 902
+ +
Sbjct: 2884 NPI 2886
Score = 119 bits (286), Expect = 7e-25
Identities = 131/479 (27%), Positives = 207/479 (43%), Gaps = 51/479 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + VT++DANDN PVF +Y S+ NA G V+ +V A D D G NG + Y R+
Sbjct: 3070 VRICVTVIDANDNAPVF-SLPVYRVSLFENAPNGAVVVRVSATDNDQGANGEITYSFSRS 3128
Query: 503 SNLTITSPFKINPNTGTV----SVAESPILE----GRHALFVEASDQPANPSERRYSLAV 554
S + F I +TG + S+ +L+ + + V A+D+ + +L +
Sbjct: 3129 SGKNLDL-FHIGADTGEITNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTL 3187
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDL-- 610
+V + P F Y ++ N G SV ++ +D N+ +SY L
Sbjct: 3188 KISDVN-------DNAPVFERQSYTAFIMENNSPGVSVLSVKAHDRDSGNNARISYFLED 3240
Query: 611 --LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVV 667
++G +V SG I Y + DF V Q+ + + +N V V+
Sbjct: 3241 VVVNGVSASTFISVNAESGEILAARSFD-YEQTK-DFSIRVKAQDGGSPPLSSNINVIVL 3298
Query: 668 DVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND + + I EN S G+++ ++ + + G V + ++ +
Sbjct: 3299 DANDNAPAFSQSVYKASI---PENFSKGSSVLKVSAADGDT---GSNGEVTYSLSQSSES 3352
Query: 727 TDDIAIAEDGT-----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ + T T LDRE Y +TV A ++G S + +T+ I D N
Sbjct: 3353 FSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVTAT-DEGSPSFSTNKTLTLKISDVN 3411
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEGKEM 836
DN PVFE +Y FIMEN+ G + +KA D D G NA Y L G
Sbjct: 3412 DNAPVFERQSYTAFIMENNSPGVSVLS---VKAHDRDSGNNARISYFLEDVVVNGVSAST 3468
Query: 837 F-DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
F V +G + S D E+ + + + A+D G LSS + I+I D+NDN P+
Sbjct: 3469 FISVHAESGEI-LAARSFDYEQTKDFSIRVKAQDGGSPPLSSNVSVKILIQDQNDNAPQ 3526
Score = 118 bits (284), Expect = 1e-24
Identities = 115/410 (28%), Positives = 186/410 (45%), Gaps = 38/410 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++P + +G + K+ A+D+DSG N + Y+ + K + AL F + ++
Sbjct: 1168 IVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLH--------KATDRAL-----FEVGAQN 1214
Query: 999 GHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + R + L + A+DGGN + ++ + V V D ND+ PVF +T Y +V E
Sbjct: 1215 GEIRTVRQESADDHDSLKLIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQTVYRASVME 1274
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTY--FIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+ V+ATDAD G +TY + Q F I TG++SV GE+D E +
Sbjct: 1275 NAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNTGIISVVGEIDHEKDT 1334
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADELSNHN 1172
K+ LTV ARD G DVNDN+P A F + P ++ N
Sbjct: 1335 KFELTVEARDQG---GLTDSSKITLDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAIIN 1391
Query: 1173 FESVMMIPVYKAT--IE--ENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLG 1228
+ + + IE E+ + +T+ ++ T+ I + L Y++ G
Sbjct: 1392 VKDADTDDNGRVSCFIEGSEDFVVKSTLRNYYSLVTNVILDREKLSEYNITVVATDS--G 1449
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
P L+S + V DV D + PVF R Y + EN + V ++ + + EN
Sbjct: 1450 KPPLTSRKTFNLKVVDVND-----NAPVFRERVYNSYLPENNSPGVSILRIRAHDPDENQ 1504
Query: 1289 KMRY-YILNENDTDIRRTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
R YIL E+D T+V ++ +G ++ VRS D E +V V+A+
Sbjct: 1505 NARISYILEESDLG---TYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQ 1551
Score = 116 bits (279), Expect = 5e-24
Identities = 124/497 (24%), Positives = 212/497 (42%), Gaps = 45/497 (9%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T +++ D QL +++ +T+LD NDN PVF+ S +Y+ ++ NA T++ V A D
Sbjct: 2310 TDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQS-VYKATVTENAPKDTIVSTVSATD 2368
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPS 546
D G N + Y + N S + + ++ ++ L+ A D
Sbjct: 2369 ADEGINSKIEYSIANIDNGQSVSIQSYYSR----ELGKGHRVDHKNILYKNAIDGGDPQL 2424
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-- 604
+ + ++ + P F Y+ + N GT + + +D E +
Sbjct: 2425 SGTAQIHITVLDAN-------DNAPVFTQKIYKASITENAVRGTVITTVSASDLDEGSYG 2477
Query: 605 DVSYDLLHGYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA---NLSIVT 660
++Y + + ++ V F + E +G + V+ + Y A + + I
Sbjct: 2478 KITYAITNTLDDVPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDDGGLTDSCKIDV 2537
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFL 719
+ + V+D ND V H + EN A G I T +S G+ G + +
Sbjct: 2538 DIHITVLDANDNAPVF---THKIYKASITEN---AVRGTIITTVTASDLDEGSYGKITYA 2591
Query: 720 IANQQDVTDDI-AIAE-DGTIFT-QKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTI 775
I N + I E +G I T +K + E + Y +T + + G +G + I
Sbjct: 2592 ITNSLGNFPMLFEINETNGEIQTREKMITLENPMEFYSITAV---DGGDPQLSGTIPIII 2648
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGE 832
+ED NDN P+ + Y+ + ENS GT + +KA+DAD+G N Y + G
Sbjct: 2649 TVEDANDNAPICFMSVYKTSVAENSPKGTVL---TTVKASDADQGQNGKVEYHIAKSTGG 2705
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLS------SEAELIIMIGDE 886
+F++D N GV+K GD +D EK Y++ + ARD G S + L + I D
Sbjct: 2706 TINLFEIDRNAGVLKLSGD-IDYEKVKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDV 2764
Query: 887 NDNKPEFNQIEENSKVR 903
NDN P F Q + V+
Sbjct: 2765 NDNAPVFEQSSYQASVQ 2781
Score = 114 bits (274), Expect = 2e-23
Identities = 121/477 (25%), Positives = 209/477 (43%), Gaps = 46/477 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D QL +++ +T+LDANDN PVF+ S +Y+ ++ NA T++ V A D D G N +
Sbjct: 2104 DPQLSGSIDIHITVLDANDNAPVFMQS-VYKATVTENAPKDTIVSTVSATDADEGINSKI 2162
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
Y + + + F IN + G V V E + + V+ASD + + L
Sbjct: 2163 EYSIANRQD-NVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLS--GSKSEPLT 2219
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V +E N P + Y+ + N GT + + +DA + ++ +++ +
Sbjct: 2220 EVILEFL-DANDNAPVCSQTV---YKTSIAENSPKGTVLTTVSASDADQGSNSRITFSIS 2275
Query: 612 HGYEEGVP-FAVEERSGVITVVD--DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
++ F ++ GV+ + D + + + D +V + LS + + V+D
Sbjct: 2276 STADKAADIFEIDSELGVVKLTGGIDYEQRHSLLTDIRSVD-GGDPQLSGSIDIHITVLD 2334
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
VND V ++ + V EN+ I + + + + + IAN
Sbjct: 2335 VNDNAPVFMQSVYKAT---VTENAPKDTI--VSTVSATDADEGINSKIEYSIAN------ 2383
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-----AGIYQVTIYIEDENDN 783
I ++ Q RE +R+ K I G +G Q+ I + D NDN
Sbjct: 2384 ---IDNGQSVSIQSYYSRELGKGHRVDHKNILYKNAIDGGDPQLSGTAQIHITVLDANDN 2440
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVD 840
PVF Y+ I EN+ GT I + A+D DEG+ Y + + +F+++
Sbjct: 2441 APVFTQKIYKASITENAVRGTVI---TTVSASDLDEGSYGKITYAITNTLDDVPVLFEIN 2497
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS----EAELIIMIGDENDNKPEF 893
E G V+ IG ++D EK Y++ + A D GGL+ + ++ I + D NDN P F
Sbjct: 2498 ETNGEVRVIG-TVDYEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVF 2553
Score = 113 bits (271), Expect = 5e-23
Identities = 128/482 (26%), Positives = 205/482 (42%), Gaps = 57/482 (11%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + P+F+ + EN P T + ++A D D G+N +I Y + +
Sbjct: 1799 LDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSI--------ANM 1850
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVN 1039
D V+R F IN +G V V + E + + + A D G L D+ + + V D N
Sbjct: 1851 EDD---VQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQGGLTDSY-INIIVLDAN 1906
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISP 1097
D+ PVF +T Y V E ++ V A+D D G N +TY I+ + + FEIS
Sbjct: 1907 DNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKVRDIFEISE 1966
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
G + + G +D E + + V A D+G DVNDN+P F++
Sbjct: 1967 TDGKVRLIGLVDYEQARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDNAP---VFEQS 2023
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI--L 1215
+ + V+ + V +NA + + K +G NG I +
Sbjct: 2024 SYQASVQRSADVGYLVTKVVAVDVDSG---QNAWLSYKLHKATDRALFEVGAQNGEIRTV 2080
Query: 1216 YSLP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
P +++N+ NL G P LS + + +TV D D PVF+ Y+
Sbjct: 2081 RQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNA-----PVFMQSVYKAT 2135
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+ EN + +++ T+ E N K+ Y I N D ++R+ F I+ NG + +V D
Sbjct: 2136 VTENAPKDTIVSTVSATDADEGINSKIEYSIANRQD-NVRQLFDINKDNGQVRVVGIIDF 2194
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV----VRIKDVNDNSPK 1379
E YE+ V+A + P+ E +LE + D V V + +NSPK
Sbjct: 2195 EKARNYEISVQASDHLSGSKSE----PLTEVILEFLDANDNAPVCSQTVYKTSIAENSPK 2250
Query: 1380 FT 1381
T
Sbjct: 2251 GT 2252
Score = 111 bits (268), Expect = 1e-22
Identities = 124/469 (26%), Positives = 207/469 (44%), Gaps = 34/469 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S++N+ V LDANDN PVF +Y+ ++ N+ GT++ V A D D G NG + Y ++
Sbjct: 1896 SYINIIV--LDANDNAPVF-SQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIR 1952
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIE 558
T + + F+I+ G V + E + V+ASD + + V+ I
Sbjct: 1953 NTID-KVRDIFEISETDGKVRLIGLVDYEQARNFEIRVQASDHGGFTDSCKIIVDVIDIS 2011
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLLHGYEE 616
+ P F + Y+ V + +G V ++ D QN +SY L H +
Sbjct: 2012 DVND------NAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKL-HKATD 2064
Query: 617 GVPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDER 673
F V ++G I V L R + + A+ + LS + + V+D ND
Sbjct: 2065 RALFEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNA 2124
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTDDIAI 732
V ++ + V EN+ I + + + + + IAN+QD V I
Sbjct: 2125 PVFMQSVYKAT---VTENAPKDTI--VSTVSATDADEGINSKIEYSIANRQDNVRQLFDI 2179
Query: 733 AED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+D G + +D EK Y ++V A + + +V + D NDN PV
Sbjct: 2180 NKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAPVCSQTV 2239
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEMFDVDENTGVVKF 848
Y+ I ENS GT + + A+DAD+G+N+ +++ + ++F++D GVVK
Sbjct: 2240 YKTSIAENSPKGTVL---TTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVVKL 2296
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
G +D E++ + + D G LS ++ I + D NDN P F Q
Sbjct: 2297 TG-GIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQ 2344
Score = 106 bits (254), Expect = 5e-21
Identities = 114/458 (24%), Positives = 195/458 (42%), Gaps = 28/458 (6%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ + D NDN PVF S+ Y+ S++ +A VG ++ KV AVD D GQN + Y L + ++
Sbjct: 2008 IDISDVNDNAPVFEQSS-YQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRA 2066
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
+ F++ G + L+ + + + + S + I +T
Sbjct: 2067 L---FEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLS-GSIDIHIT--VLDA 2120
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVP-FAVE 623
+ P FM + Y+ V N T V + DA E + + Y + + + F +
Sbjct: 2121 NDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNVRQLFDIN 2180
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQE--NANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ +G + VV + Y+ A + +T + +D ND V + +
Sbjct: 2181 KDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAPVCSQTVY 2240
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDI--AIAEDGTI 738
I ENS G + T +S G+ + + F I++ D DI +E G +
Sbjct: 2241 KTSI---AENSPK---GTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVV 2294
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+D E+R +T I + G +G + I + D NDN PVF + Y+ + E
Sbjct: 2295 KLTGGIDYEQRHSL-LTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQSVYKATVTE 2353
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREK 857
N+ T + + + ATDADEG N+ Y++ + + + G +D K
Sbjct: 2354 NAPKDTIV---STVSATDADEGINSKIEYSIANIDNGQSVSIQSYYSRELGKGHRVD-HK 2409
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
I+YK ++ D LS A++ I + D NDN P F Q
Sbjct: 2410 NILYKNAIDGGDP-QLSGTAQIHITVLDANDNAPVFTQ 2446
Score = 101 bits (243), Expect = 1e-19
Identities = 100/410 (24%), Positives = 172/410 (41%), Gaps = 35/410 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P+ T ++ ++A D D G NG++ Y F + E K F +N G
Sbjct: 52 LPENSPVDTVVVTVSATDADEGQNGKVTYVFGHV-----------SEEDKTLFSLNRNTG 100
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V ++ E S + L + A D L V + V D ND+ PV N + E+
Sbjct: 101 EITVTGAIDYEEKSAYELRVLAKDAAGLTSYSMVIIDVTDTNDNAPVIISKSLNIPIPES 160
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
+G ++ D D N + IQ ++PF++ P L GELDRE
Sbjct: 161 ALPGTEVGIINVQDRDSENNGQVRCSIQ---QNVPFKLVPSIKNYYSLVTTGELDRELLS 217
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+Y +T+ A D G DVNDN P F + + PE +
Sbjct: 218 EYNITITATDEG-SPPLSSTKNIHLTVADVNDNPPVFQ--QAVYKVSLPENSPVDT---- 270
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG---NGNGLILYSLPQRKNQQNLGLPS 1231
V+ + A +N + + ND N + L +++ + LP
Sbjct: 271 VVVTVSATDADEGQNGEVTYEFGHISENDITIFSLDQNSGKITLIGSLDYEDEASFDLPI 330
Query: 1232 LSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEENVNAPVELVSLNLT--EHYEN 1287
++ + +V+ + V +V +++D PVF + Y ++EN A + S++ T + +N
Sbjct: 331 QATDGLGLVSYSTVVIDVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQN 390
Query: 1288 FKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ Y +L+ N + I+ G ++ VRS D E +++V+V A
Sbjct: 391 GTVVYSLLSSDVNGAPVSSFLSINGDTGVIHAVRSFDYEQMKSFKVLVLA 440
Score = 100 bits (240), Expect = 3e-19
Identities = 121/456 (26%), Positives = 190/456 (41%), Gaps = 57/456 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT I +NA D D+G G+I Y F + K +A L F I+ G
Sbjct: 1272 VMENAPKGTYITTVNATDADAGSYGRITYNFYKQ------KGAAAQL-----FNIDSNTG 1320
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V + E + F L + A D G L D+ + + V DVND+ PV ++ V E
Sbjct: 1321 IISVVGEIDHEKDTKFELTVEARDQGGLTDSSKITLDVIDVNDNAPVINAMSFSSTVSED 1380
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ ++ DAD N ++ FI+ S+ + L N LDRE +Y
Sbjct: 1381 APPDTTIAIINVKDADTDDNGRVSCFIEGSEDFVVKSTLRNYYSLVTNVILDREKLSEYN 1440
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
+TVVA D+G DVNDN+P F + + PE +N S++
Sbjct: 1441 ITVVATDSGKPPLTSRKTFNLKVV-DVNDNAPVFR--ERVYNSYLPE----NNSPGVSIL 1493
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI----LYSLPQRKN------QQNL 1227
I + +NA I + + + +G++ + Q KN Q+
Sbjct: 1494 RIRAHDPDENQNARISYILEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDG 1553
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G P LSS + VTV DV D + PVF Y + EN + ++N T+ ++
Sbjct: 1554 GSPPLSSNVTIDVTVLDVND-----NAPVFNQTVYRASVTENAPKGTYITTVNATD-ADS 1607
Query: 1288 FKMRYYILNEND--TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+ L+ +D R F ID G + ++ + D E +E+ V+A Q
Sbjct: 1608 GSNGHITLSFSDLKEQSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQ------- 1660
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
G+T K+++ + DVNDN+P T
Sbjct: 1661 -----------GGLTSTS-KLIIEVVDVNDNAPVIT 1684
Score = 100 bits (240), Expect = 3e-19
Identities = 133/497 (26%), Positives = 203/497 (40%), Gaps = 102/497 (20%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + P+F+ + EN P T + ++A D D G+N +I Y +
Sbjct: 2118 LDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANR-------- 2169
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALD--GGNLNDNIS-VRVFVK 1036
D V++ F IN+ +G V V + E + +++ A D G+ ++ ++ V +
Sbjct: 2170 -QD--NVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFL 2226
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FE 1094
D ND+ PV +T Y ++ E VL V A+DAD G N+ +T+ I + FE
Sbjct: 2227 DANDNAPVCSQTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFE 2286
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
I GV+ + G +D E +LT + +G DVNDN+P
Sbjct: 2287 IDSELGVVKLTGGIDYEQRHS-LLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAP----- 2340
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-------- 1206
V M VYKAT+ ENAP T V+ V A D D
Sbjct: 2341 ---------------------VFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEY 2379
Query: 1207 ----IGNGNGLILYSLPQR---------------KNQQNLGLPSLSSTAILMVTVADVPD 1247
I NG + + S R KN + G P LS TA + +TV D D
Sbjct: 2380 SIANIDNGQSVSIQSYYSRELGKGHRVDHKNILYKNAIDGGDPQLSGTAQIHITVLDAND 2439
Query: 1248 EVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRT 1305
+ PVF + Y+ I EN + VS + + K+ Y I N D D+
Sbjct: 2440 -----NAPVFTQKIYKASITENAVRGTVITTVSASDLDEGSYGKITYAITNTLD-DVPVL 2493
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
F I+ NG + ++ + D E Y++ V+A + L K DV
Sbjct: 2494 FEINETNGEVRVIGTVDYEKARHYQIHVQAS---------------DDGGLTDSCKIDVD 2538
Query: 1366 VVVRIKDVNDNSPKFTN 1382
+ + + D NDN+P FT+
Sbjct: 2539 IHITVLDANDNAPVFTH 2555
Score = 99.5 bits (237), Expect = 6e-19
Identities = 130/529 (24%), Positives = 216/529 (40%), Gaps = 52/529 (9%)
Query: 423 DKVGTKTENIEYYDEQLMSF-VNVEVTLL--DANDNNPVFVPSNLYEFSMKSNAKVGTVI 479
+K+ + DE SF N +TL D NDN PVF + F +++N+ G +
Sbjct: 2943 EKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIIENNSP-GVSV 3001
Query: 480 GKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFV 536
VKA D D G N + Y L + S + + V ++P+ + H L +
Sbjct: 3002 LSVKAHDRDSGNNARISYFLDLSG-----SEHGNDGSKYVEMVLQAPLDRETQHEHKLTL 3056
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
A D NP +R ++ + + +P + + +E V + S
Sbjct: 3057 TAFDG-GNP-QRTGTVRICVTVIDANDNAPVFSLPVYRVSLFENAPNGAVVVRVSATD-- 3112
Query: 597 VNDAFEQNDVSYDLLHGYEEGVP-FAVEERSGVIT-----VVDDL-SRYNRPMYDFEAVA 649
ND +++Y + + F + +G IT + D L R Y+ A
Sbjct: 3113 -NDQGANGEITYSFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREKISEYNITVTA 3171
Query: 650 LQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSI 708
E + + S T+ + DVND V + +++ I ++ NS G ++ + + S
Sbjct: 3172 TDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFI--MENNSPGVSVLSVKAHDRDS- 3228
Query: 709 YGNGTGNVRFL---IANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
GN FL + N + I++ AE G I + D E+ + + V A+
Sbjct: 3229 -GNNARISYFLEDVVVNGVSASTFISVNAESGEILAARSFDYEQTKDFSIRVKAQDGGSP 3287
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+ I + + D NDN P F + Y+ I EN G+ + + A D D G+N
Sbjct: 3288 PLSSNI---NVIVLDANDNAPAFSQSVYKASIPENFSKGSSVLK---VSAADGDTGSNGE 3341
Query: 825 FMYTLFGEGKE---MFDVDENTG--VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEA 877
Y+L + +F++D NTG V D LDRE Y +++ A D G S+
Sbjct: 3342 VTYSLSQSSESFSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVTATDEGSPSFSTNK 3401
Query: 878 ELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
L + I D NDN P F E S E N + G +++ VK ++
Sbjct: 3402 TLTLKISDVNDNAPVF---ERQSYTAFIME---NNSPGVSVLSVKAHDR 3444
Score = 97.9 bits (233), Expect = 2e-18
Identities = 107/388 (27%), Positives = 178/388 (45%), Gaps = 44/388 (11%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ E L ++A+DGG + +++ V V D ND+ PVF + Y ++ E V+ V
Sbjct: 6 QKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVTV 65
Query: 1068 DATDADFGQNANLTY-FIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
ATDAD GQN +TY F S+ D F ++ TG ++V G +D E + Y L V+A+D
Sbjct: 66 SATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYELRVLAKD- 124
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFD---ELLEWKHP--EADELSNHNFESVMMIP 1180
D NDN+P + + E P E ++ + +S
Sbjct: 125 --AAGLTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDSENNGQ 182
Query: 1181 VYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
V + +I++N P + ++ ++ T + L Y++ + G P LSST +
Sbjct: 183 V-RCSIQQNVPFKLVPSIKNYYSLVTTGELDRELLSEYNITITATDE--GSPPLSSTKNI 239
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILN 1296
+TVADV D + PVF Y++ + EN V+ V VS + +N ++ Y +
Sbjct: 240 HLTVADVND-----NPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGH 294
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVL 1356
++ DI F +D +G + L+ S D E + ++++ ++ A D L
Sbjct: 295 ISENDI-TIFSLDQNSGKITLIGSLDYEDEASFDLPIQ-----------------ATDGL 336
Query: 1357 EGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
G+ Y VV+ + DVNDN P F N
Sbjct: 337 -GLVSYST-VVIDVSDVNDNPPVFQQQN 362
Score = 92.3 bits (219), Expect = 9e-17
Identities = 127/491 (25%), Positives = 204/491 (41%), Gaps = 55/491 (11%)
Query: 431 NIEYYDEQ-LMSFVNVEVTLLDANDNNPVFVPSNLYEFS--MKSNAKVGTVIGKVKAVDP 487
NI+ D+ L V + + D NDN PV +L FS + +A TVI + D
Sbjct: 2848 NIDATDKGGLTDSSKVIIDITDVNDNPPVI---SLISFSNPIPEDAAPETVIAMLNVKDL 2904
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILE----GRHALFVEASDQP 542
D G+NG V ++ PFK+ + S+ +L+ + + V A+D+
Sbjct: 2905 DSGKNGQV------KCYISADMPFKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEG 2958
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
+ +L + +V + P F Y ++ N G SV ++ +D
Sbjct: 2959 SPSFSTNKTLTLKISDVN-------DNAPVFERQSYTAFIIENNSPGVSVLSVKAHDRDS 3011
Query: 603 QND--VSYDL-LHGYEEGVPFAVEERSGVITVV--DDLSRYNRPMYDFEAVALQE-NANL 656
N+ +SY L L G E G + S + +V L R + + A N
Sbjct: 3012 GNNARISYFLDLSGSEHG-----NDGSKYVEMVLQAPLDRETQHEHKLTLTAFDGGNPQR 3066
Query: 657 SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+ V V+D ND V + +F N GA + ++ T+ NG
Sbjct: 3067 TGTVRICVTVIDANDNAPVFSLPVYRVSLFENAPN--GAVVVRVSATDNDQ-GANGEITY 3123
Query: 717 RFLIANQQDV------TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
F ++ +++ D I ++ T + LDREK Y +TV A ++G S +
Sbjct: 3124 SFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREKISEYNITVTAT-DEGSPSFSTN 3182
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL- 829
+T+ I D NDN PVFE +Y FIMEN+ G + +KA D D G NA Y L
Sbjct: 3183 KTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLS---VKAHDRDSGNNARISYFLE 3239
Query: 830 ----FGEGKEMF-DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
G F V+ +G + S D E+ + + + A+D G + + +++
Sbjct: 3240 DVVVNGVSASTFISVNAESGEI-LAARSFDYEQTKDFSIRVKAQDGGSPPLSSNINVIVL 3298
Query: 885 DENDNKPEFNQ 895
D NDN P F+Q
Sbjct: 3299 DANDNAPAFSQ 3309
Score = 90.2 bits (214), Expect = 4e-16
Identities = 54/152 (35%), Positives = 85/152 (55%), Gaps = 10/152 (6%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE++ + ++ + G +G + + + D NDN PVF A Y+ + ENS +
Sbjct: 1 LDREQQKEVTL-ILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVD 59
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFIGDSLDREKKI 859
T + + ATDADEG N Y +FG E K +F ++ NTG + G ++D E+K
Sbjct: 60 TVVV---TVSATDADEGQNGKVTY-VFGHVSEEDKTLFSLNRNTGEITVTG-AIDYEEKS 114
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
Y+L ++A+D GL+S + +II + D NDN P
Sbjct: 115 AYELRVLAKDAAGLTSYSMVIIDVTDTNDNAP 146
Score = 89.4 bits (212), Expect = 7e-16
Identities = 97/301 (32%), Positives = 132/301 (43%), Gaps = 52/301 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT I + A DLD G G+I Y + + P F INE +G
Sbjct: 2562 ITENAVRGTIITTVTASDLDEGSYGKITYAITNSLGNFPM-----------LFEINETNG 2610
Query: 1000 HVIVAR---SLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ +L EF +I+A+DGG+ L+ I + + V+D ND+ P+ + Y +V
Sbjct: 2611 EIQTREKMITLENPMEF-YSITAVDGGDPQLSGTIPIIITVEDANDNAPICFMSVYKTSV 2669
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD--TDLPFEISPLTGVLSVNGELDRET 1112
E VL V A+DAD GQN + Y I S T FEI GVL ++G++D E
Sbjct: 2670 AENSPKGTVLTTVKASDADQGQNGKVEYHIAKSTGGTINLFEIDRNAGVLKLSGDIDYEK 2729
Query: 1113 EDKYILTVVARDNGXXX---XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
Y + V ARD G DVNDN+P F E S
Sbjct: 2730 VKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDVNDNAPVF---------------EQS 2774
Query: 1170 NHNFESVMMIPVYKATIE-ENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLG 1228
+ Y+A+++ ENAP G V +V A D D NG I YS R + +NL
Sbjct: 2775 S-----------YQASVQFENAPNGAVVVRVSATDND--QGANGEITYSF-SRSSGKNLD 2820
Query: 1229 L 1229
L
Sbjct: 2821 L 2821
Score = 89.4 bits (212), Expect = 7e-16
Identities = 88/293 (30%), Positives = 137/293 (46%), Gaps = 46/293 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ T I LN DLDSG NGQ++ ++++ P K+ + A Y +I ++
Sbjct: 2886 IPEDAAPETVIAMLNVKDLDSGKNGQVKCYISADM---PFKVKSSAQNF--YSLITDQ-- 2938
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN-FNVEE 1056
++ R SE+ + ++A D G+ + N ++ + + DVND+ PVF++ Y F +E
Sbjct: 2939 --LLDRE--KISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIIEN 2994
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
VL V A D D G NA ++YF+ S ++ + S ++ + LDRET+ ++
Sbjct: 2995 NSPGVSVLS-VKAHDRDSGNNARISYFLDLSGSEHGNDGSKYVEMV-LQAPLDRETQHEH 3052
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
LT+ A D G D NDN+P V
Sbjct: 3053 KLTLTAFDGGNPQRTGTVRICVTVI-DANDNAP--------------------------V 3085
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
+PVY+ ++ ENAP G V +V A D D NG I YS R + +NL L
Sbjct: 3086 FSLPVYRVSLFENAPNGAVVVRVSATDND--QGANGEITYSF-SRSSGKNLDL 3135
Score = 86.2 bits (204), Expect = 6e-15
Identities = 97/396 (24%), Positives = 169/396 (42%), Gaps = 36/396 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I++ N A +Q + + +G + K+ A+D+DSG N + Y+ +
Sbjct: 2007 VIDISDVNDNAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLH------ 2060
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLP----PESEFRLNISALDGGN--LNDNISV 1031
K + AL F + ++G + R P ++E L ++A+DGG+ L+ +I +
Sbjct: 2061 --KATDRAL-----FEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDI 2113
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
+ V D ND+ PVF ++ Y V E ++ V ATDAD G N+ + Y I ++
Sbjct: 2114 HITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNV 2173
Query: 1092 P--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F+I+ G + V G +D E Y ++V A D+ D NDN+P
Sbjct: 2174 RQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAP 2233
Query: 1150 --KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF- 1206
+ + P+ L+ + + T ++ A +F D++
Sbjct: 2234 VCSQTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISS-TADKAADIFEIDSELG 2292
Query: 1207 IGNGNGLILY----SLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY 1262
+ G I Y SL + G P LS + + +TV DV D + PVF+ Y
Sbjct: 2293 VVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVND-----NAPVFMQSVY 2347
Query: 1263 ELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILN 1296
+ + EN + +++ T+ E N K+ Y I N
Sbjct: 2348 KATVTENAPKDTIVSTVSATDADEGINSKIEYSIAN 2383
Score = 85.4 bits (202), Expect = 1e-14
Identities = 54/170 (31%), Positives = 84/170 (49%), Gaps = 13/170 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G A L Y+L DR LF + + NG + ++ D +H+ L++ A
Sbjct: 1184 AVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQESAD-DHDS------LKLIAV 1236
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP ++ +++ +LD NDN P F Y S++EN P G + V ATD D G G
Sbjct: 1237 DGGNPQRSGSVIIDVTVLDANDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYG 1296
Query: 340 EFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
TY KGA F+ID +G ++V + +D E + + V A++
Sbjct: 1297 RITYNFYKQKGAAAQLFNIDSNTGIISVVGE--IDHEKDTKFELTVEARD 1344
Score = 85.4 bits (202), Expect = 1e-14
Identities = 91/378 (24%), Positives = 170/378 (44%), Gaps = 48/378 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT + + A D D G NG++ Y +K + + + F I+ G
Sbjct: 2669 VAENSPKGTVLTTVKASDADQGQNGKVEYHI--------AKSTGGTINL---FEIDRNAG 2717
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLND------NISVRVFVKDVNDHFPVFKKTWYN 1051
+ ++ + E +++++ A D G +D ++++ + + DVND+ PVF+++ Y
Sbjct: 2718 VLKLSGDIDYEKVKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDVNDNAPVFEQSSYQ 2777
Query: 1052 FNVE-EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP-FEISPLTGVLSVNGEL 1108
+V+ E V+ +V ATD D G N +TY F + S +L F I P TG ++V G L
Sbjct: 2778 ASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFHIGPDTGEITVKGHL 2837
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
D E ++ L + A D G DVNDN P L+ + +P ++
Sbjct: 2838 DYERAKQFELNIDATDKG---GLTDSSKVIIDITDVNDNPPVI----SLISFSNPIPEDA 2890
Query: 1169 SNHNFESVMMIP--------VYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSL 1218
+ +++ + K I + P + ++ ++ TD + + + Y++
Sbjct: 2891 APETVIAMLNVKDLDSGKNGQVKCYISADMPFKVKSSAQNFYSLITDQLLDREKISEYNI 2950
Query: 1219 PQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
+ G PS S+ L + ++DV D + PVF + Y I EN + V ++S
Sbjct: 2951 TVTATDE--GSPSFSTNKTLTLKISDVND-----NAPVFERQSYTAFIIENNSPGVSVLS 3003
Query: 1279 LNL--TEHYENFKMRYYI 1294
+ + N ++ Y++
Sbjct: 3004 VKAHDRDSGNNARISYFL 3021
Score = 84.2 bits (199), Expect = 2e-14
Identities = 81/318 (25%), Positives = 131/318 (41%), Gaps = 22/318 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ + + D NDN P+F T Y V E +P G + + + +T TI K
Sbjct: 1898 INIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDK 1957
Query: 143 DIRAFDRDKPNTPNSDV---------HYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDA 192
F+ + + + ++ I V +D G F S K ++ + + D +
Sbjct: 1958 VRDIFEISETDGKVRLIGLVDYEQARNFEIRVQASDHGGFT--DSCKIIVDVIDISDVND 2015
Query: 193 GDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
F Q AS +R + A+D D G A L Y+L DR LF + + NG
Sbjct: 2016 NAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNG 2075
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ ++ LD E + N + V +P + + I +LD NDN P F Y
Sbjct: 2076 EIRTVRQKPLDREKQNEINLVLTAVDGG---DPQLSGSIDIHITVLDANDNAPVFMQSVY 2132
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQT 367
++ EN P V V ATD D+G N + Y + D+ + F I+ +G VR
Sbjct: 2133 KATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNVRQLFDINKDNG--QVRVVG 2190
Query: 368 VLDREAHSSLRMKVYAKE 385
++D E + + V A +
Sbjct: 2191 IIDFEKARNYEISVQASD 2208
Score = 82.6 bits (195), Expect = 8e-14
Identities = 61/182 (33%), Positives = 89/182 (48%), Gaps = 17/182 (9%)
Query: 218 IHAIDQDLGVGATLRYEL-ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D G A + Y L +SG++ +GS ++E L + Q + L +
Sbjct: 3004 VKAHDRDSGNNARISYFLDLSGSEH------GNDGSKYVEMVLQAPLDRETQ-HEHKLTL 3056
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A NP +T R+ + ++D NDN P F + Y +S+ EN PNG V++V ATD DQG
Sbjct: 3057 TAFDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRVSLFENAPNGAVVVRVSATDNDQG 3116
Query: 337 ENGEFTYQLDDPKG----AFSIDPRSGWLT----VRNQTVLDREAHSSLRMKVYA-KETN 387
NGE TY G F I +G +T + +LDRE S + V A E +
Sbjct: 3117 ANGEITYSFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREKISEYNITVTATDEGS 3176
Query: 388 PS 389
PS
Sbjct: 3177 PS 3178
Score = 80.6 bits (190), Expect = 3e-13
Identities = 61/183 (33%), Positives = 88/183 (48%), Gaps = 18/183 (9%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D+D G A + Y L ++G F S+++ +G + + D + Q F
Sbjct: 3221 VKAHDRDSGNNARISYFLEDVVVNGVSASTFISVNAESGEILAARSFDYE-----QTKDF 3275
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
++V+A +P + + + +LD NDN P F Y SI EN G SVL+V A D
Sbjct: 3276 SIRVKAQDGGSP--PLSSNINVIVLDANDNAPAFSQSVYKASIPENFSKGSSVLKVSAAD 3333
Query: 333 KDQGENGEFTYQLDDP----KGAFSIDPRSGWLTVR-NQTVLDREAHSSLRMKVYA-KET 386
D G NGE TY L G F+ID +G +TV +LDRE S + V A E
Sbjct: 3334 GDTGSNGEVTYSLSQSSESFSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVTATDEG 3393
Query: 387 NPS 389
+PS
Sbjct: 3394 SPS 3396
Score = 79.4 bits (187), Expect = 7e-13
Identities = 99/386 (25%), Positives = 169/386 (43%), Gaps = 61/386 (15%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFN--SEVYIPPS 979
+D + P+F +P EN P G +++++A D D G NG+I Y F+ S +
Sbjct: 3077 IDANDNAPVFSLPVYRVSLFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLF 3136
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFV 1035
+ AD E+ ++ + I + L E SE+ + ++A D G+ + N ++ + +
Sbjct: 3137 HIGADTGEITNFYSL-------ITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKI 3189
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
DVND+ PVF++ Y + E + V A D D G NA ++YF++ +
Sbjct: 3190 SDVNDNAPVFERQSYTAFIMENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVN-GVSA 3248
Query: 1096 SPLTGVLSVNGEL------DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
S V + +GE+ D E + + V A+D G D NDN+P
Sbjct: 3249 STFISVNAESGEILAARSFDYEQTKDFSIRVKAQDGGSPPLSSNINVIVL---DANDNAP 3305
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
AF + VYKA+I EN G++V KV A D D
Sbjct: 3306 ---AFSQ-----------------------SVYKASIPENFSKGSSVLKVSAADGD--TG 3337
Query: 1210 GNGLILYSLPQRKNQQNLGLPSL-SSTAILMVTVA-DVPDEVEMSDKPVFISRYYELEIE 1267
NG + YSL Q ++ GL ++ S+T + V V D+ D +S+ + ++ E
Sbjct: 3338 SNGEVTYSLSQ-SSESFSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVTATDEGSPS 3396
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYY 1293
+ N + L ++ ++ F+ + Y
Sbjct: 3397 FSTNKTLTLKISDVNDNAPVFERQSY 3422
Score = 79.0 bits (186), Expect = 9e-13
Identities = 78/289 (26%), Positives = 123/289 (42%), Gaps = 52/289 (17%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F+ + EN P T + ++A D D G+N +I Y +
Sbjct: 2333 LDVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANID------- 2385
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVN 1039
+ ++ ++ Y+ GH + +++ L +A+DGG+ L+ + + V D N
Sbjct: 2386 NGQSVSIQSYYSRELGKGHRVDHKNI-------LYKNAIDGGDPQLSGTAQIHITVLDAN 2438
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISP 1097
D+ PVF + Y ++ E V+ V A+D D G +TY I + D+P FEI+
Sbjct: 2439 DNAPVFTQKIYKASITENAVRGTVITTVSASDLDEGSYGKITYAITNTLDDVPVLFEINE 2498
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXX-XXXXXXXXXXXDVNDNSPKFYAFDE 1156
G + V G +D E Y + V A D+G D NDN+P F
Sbjct: 2499 TNGEVRVIGTVDYEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVF----- 2553
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
H +YKA+I ENA GT + V A+D D
Sbjct: 2554 -------------THK--------IYKASITENAVRGTIITTVTASDLD 2581
Score = 76.6 bits (180), Expect = 5e-12
Identities = 81/331 (24%), Positives = 143/331 (43%), Gaps = 28/331 (8%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP--TGEKAFIFLIAPIGPSLTIPLTVPRG 137
++ + + + D NDN P+F+ + Y TV E P T A G + I ++
Sbjct: 1791 FIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANM 1850
Query: 138 LTIFKDIRAFDRDKPNTPNSDV-------HYSI-VSGNDDGHFALESSHKPVLLLRKVLD 189
+ + A +RD + +Y I V +D G L S+ ++ VLD
Sbjct: 1851 EDDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQG--GLTDSYINII----VLD 1904
Query: 190 YDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND--RKLFSL 246
+ F Q V + + + A D D GV + Y + + D R +F +
Sbjct: 1905 ANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKVRDIFEI 1964
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE-IELLDLNDNLPE 305
+G + L +D + QA F ++VQAS + + V+ I++ D+NDN P
Sbjct: 1965 SETDGKVRLIGLVDYE-----QARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDNAPV 2019
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTV 363
FE Y S+ + G+ V +V+A D D G+N +Y+L + F + ++G +
Sbjct: 2020 FEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRT 2079
Query: 364 RNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
Q LDRE + + + + A + +P + G+
Sbjct: 2080 VRQKPLDREKQNEINLVLTAVDGGDPQLSGS 2110
Score = 76.2 bits (179), Expect = 7e-12
Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 23/245 (9%)
Query: 163 IVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAI 221
IV D G L SS+K + + VLD + F Q V A+ + + A
Sbjct: 1775 IVKAQDGGSPPL-SSNKFIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSAT 1833
Query: 222 DQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
D D G+ + + Y + + D ++LF+++ NG + + +D + +A + ++VQAS
Sbjct: 1834 DADEGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDFE-----RARNYEIRVQAS 1888
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ + I +LD NDN P F Y ++ EN P G V V A+D DQG NG
Sbjct: 1889 DQGG---LTDSYINIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNG 1945
Query: 340 EFTYQ----LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
E TY +D + F I G VR ++D E + ++V A + G F
Sbjct: 1946 EITYSIRNTIDKVRDIFEISETDG--KVRLIGLVDYEQARNFEIRVQASDH-----GGFT 1998
Query: 396 DSQRI 400
DS +I
Sbjct: 1999 DSCKI 2003
Score = 74.5 bits (175), Expect = 2e-11
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 9/167 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D A + Y L + S+++ +G + + D + N++ V+
Sbjct: 1495 IRAHDPDENQNARISYILEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVT-----VK 1549
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P ++ +++ +LD+NDN P F Y S+ EN P G + V ATD D G
Sbjct: 1550 AQDGGSPPLSSNVTIDVTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGS 1609
Query: 338 NGEFTYQLDDPK----GAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
NG T D K G F+ID +G ++V +++ +R+K
Sbjct: 1610 NGHITLSFSDLKEQSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVK 1656
Score = 73.7 bits (173), Expect = 3e-11
Identities = 132/523 (25%), Positives = 204/523 (39%), Gaps = 96/523 (18%)
Query: 929 LDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F + EN P GT I +NA D DSG NG I F+
Sbjct: 1569 LDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFS---------- 1618
Query: 982 SADALEVKR-YFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDV 1038
D E R F I+E G V V ++ E + F + + A D G L + + V DV
Sbjct: 1619 --DLKEQSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGGLTSTSKLIIEVVDV 1676
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLG-------------KVDATDADFGQNANLTYFIQ 1085
ND+ PV + V E + V A D D+ QN+ ++Y+++
Sbjct: 1677 NDNAPVITLMSLSSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDLDWNQNSRVSYYLE 1736
Query: 1086 PSD-TDLPFE----ISPLTGVLSVNGELDRETEDKYILTVVARDNGXX-XXXXXXXXXXX 1139
+ + +P I+ GVL D E ++ V A+D G
Sbjct: 1737 DAHISGVPISSYVSINAENGVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHI 1796
Query: 1140 XXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
D NDN+P V M VYKAT+ ENAP T V+ V
Sbjct: 1797 TVLDANDNAP--------------------------VFMQSVYKATVTENAPKDTIVSTV 1830
Query: 1200 FANDTDFIGNGNGLILYSLPQRKNQ-QNLGLPSLSSTAILMVTVADVPD------EVEMS 1252
A D D N I YS+ ++ Q L + + + +V + D V+ S
Sbjct: 1831 SATDAD--EGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQAS 1888
Query: 1253 DKPVFISRYYE-LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPR 1311
D+ Y + ++ N NAPV ++ T EN + + +D+ +
Sbjct: 1889 DQGGLTDSYINIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGV----- 1943
Query: 1312 NGTL-YLVRSPDREVKDTYEVIVRAERQK------YSRELPHMIYPVAEDVLEGMTKYDV 1364
NG + Y +R+ +V+D +E+ + + Y + I A D G
Sbjct: 1944 NGEITYSIRNTIDKVRDIFEISETDGKVRLIGLVDYEQARNFEIRVQASD--HGGFTDSC 2001
Query: 1365 KV---VVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
K+ V+ I DVNDN+P F + ++ +A GY V ++
Sbjct: 2002 KIIVDVIDISDVNDNAPVFEQSS--YQASVQRSADVGYLVTKV 2042
Score = 72.9 bits (171), Expect = 6e-11
Identities = 73/279 (26%), Positives = 113/279 (40%), Gaps = 46/279 (16%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT I ++A DLD G G+I Y + + +V F INE +G
Sbjct: 2453 ITENAVRGTVITTVSASDLDEGSYGKITYAITNTLD-----------DVPVLFEINETNG 2501
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDN----ISVRVFVKDVNDHFPVFKKTWYNFN 1053
V V ++ E +++++ A D G L D+ + + + V D ND+ PVF Y +
Sbjct: 2502 EVRVIGTVDYEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKAS 2561
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRE 1111
+ E ++ V A+D D G +TY I S + P FEI+ G + ++
Sbjct: 2562 ITENAVRGTIITTVTASDLDEGSYGKITYAITNSLGNFPMLFEINETNGEIQTREKMITL 2621
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
++ A D G D NDN+P
Sbjct: 2622 ENPMEFYSITAVDGG-DPQLSGTIPIIITVEDANDNAP---------------------- 2658
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+ + VYK ++ EN+P GT + V A+D D NG
Sbjct: 2659 ----ICFMSVYKTSVAENSPKGTVLTTVKASDADQGQNG 2693
Score = 71.7 bits (168), Expect = 1e-10
Identities = 71/305 (23%), Positives = 127/305 (41%), Gaps = 20/305 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G Q+S + + + + D NDN P+F+ + Y TV E P + + ++
Sbjct: 2097 LTAVDGGDPQLSGSIDIHITVLDANDNAPVFMQSVYKATVTENAP--KDTIVSTVSATDA 2154
Query: 127 SLTIPLTVPRGLTIFKD-IRA-FDRDKPNTPNSDVHYSIVSGNDDGHFALESSH-----K 179
I + + +D +R FD +K N V + ++++S K
Sbjct: 2155 DEGINSKIEYSIANRQDNVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSK 2214
Query: 180 PVLLLRKVLDY-DAGDKE---FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
L +L++ DA D Q V S + + A D D G + + + +
Sbjct: 2215 SEPLTEVILEFLDANDNAPVCSQTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSI 2274
Query: 236 ISGNDRK--LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
S D+ +F +DS G + L +D + H+L + +++ +P + +
Sbjct: 2275 SSTADKAADIFEIDSELGVVKLTGGIDYEQRHSL-----LTDIRSVDGGDPQLSGSIDIH 2329
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFS 353
I +LD+NDN P F Y ++ EN P V V ATD D+G N + Y + + S
Sbjct: 2330 ITVLDVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANIDNGQS 2389
Query: 354 IDPRS 358
+ +S
Sbjct: 2390 VSIQS 2394
Score = 71.3 bits (167), Expect = 2e-10
Identities = 81/309 (26%), Positives = 121/309 (39%), Gaps = 28/309 (9%)
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS----LTIPLTVPRGLTIFK 142
I DVNDN P+F + Y +V G + + L+ L +F+
Sbjct: 2010 ISDVNDNAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFE 2069
Query: 143 ------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
+IR R KP ++V DG S + + VLD +
Sbjct: 2070 VGAQNGEIRTV-RQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHIT--VLDANDNAPV 2126
Query: 197 F-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSL 253
F Q V A+ + + A D D G+ + + Y + + D R+LF ++ NG +
Sbjct: 2127 FMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNVRQLFDINKDNGQV 2186
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ +D + +A + + VQAS L+ V +E LD NDN P Y
Sbjct: 2187 RVVGIIDFE-----KARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAPVCSQTVYK 2241
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTV 368
SI EN P G + V A+D DQG N T+ + D F ID G V+
Sbjct: 2242 TSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELG--VVKLTGG 2299
Query: 369 LDREAHSSL 377
+D E SL
Sbjct: 2300 IDYEQRHSL 2308
Score = 66.9 bits (156), Expect = 4e-09
Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
Q L + A P ++ + + +LD NDN P F Y +S+ EN P V+
Sbjct: 5 QQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVT 64
Query: 328 VMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
V ATD D+G+NG+ TY ++ K FS++ +G +TV +D E S+ ++V A
Sbjct: 65 VSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTG--AIDYEEKSAYELRVLA 122
Query: 384 KE 385
K+
Sbjct: 123 KD 124
Score = 66.1 bits (154), Expect = 7e-09
Identities = 78/331 (23%), Positives = 133/331 (40%), Gaps = 21/331 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G S +++ V + D NDN P+F Y V++ E +P
Sbjct: 13 LTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVTVSATDADE 72
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
+T G +D F ++ NT V +I + + L K L
Sbjct: 73 GQNGKVTYVFGHVSEEDKTLFSLNR-NTGEITVTGAI-DYEEKSAYELRVLAKDAAGLTS 130
Query: 187 ----VLDYDAGDKEFQLVIMASGKRIHKEILFPEP----IHAIDQDLGVGATLRYELISG 238
++D + ++I S E P I+ D+D +R +
Sbjct: 131 YSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDSENNGQVRCSIQQN 190
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
KL + S+ L +LD E + N + + A+ +P ++ + + + D
Sbjct: 191 VPFKL--VPSIKNYYSLVTTGELDRELLSEYN---ITITATDEGSPPLSSTKNIHLTVAD 245
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSI 354
+NDN P F+ Y +S+ EN P V+ V ATD D+G+NGE TY+ ++ FS+
Sbjct: 246 VNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHISENDITIFSL 305
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D SG +T+ LD E +S + + A +
Sbjct: 306 DQNSGKITLIGS--LDYEDEASFDLPIQATD 334
Score = 66.1 bits (154), Expect = 7e-09
Identities = 80/304 (26%), Positives = 126/304 (41%), Gaps = 27/304 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS------LTI 130
+++Y V + + D NDN P+ + ++ + E G + I + +I
Sbjct: 128 LTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDSENNGQVRCSI 187
Query: 131 PLTVPRGLT-IFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVL 188
VP L K+ + Y+I ++ D+G L SS K + L V
Sbjct: 188 QQNVPFKLVPSIKNYYSLVTTGELDRELLSEYNITITATDEGSPPL-SSTKNIHLT--VA 244
Query: 189 DYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYEL--ISGNDRKLFS 245
D + FQ + + + + A D D G + YE IS ND +FS
Sbjct: 245 DVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHISENDITIFS 304
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
LD +G + L LD + E + F L +QA+ + + + V I++ D+NDN P
Sbjct: 305 LDQNSGKITLIGSLDYEDEAS-----FDLPIQAT--DGLGLVSYSTVVIDVSDVNDNPPV 357
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTV 363
F+ Y + EN G S+ V ATD D +NG Y L D GA P S +L++
Sbjct: 358 FQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGA----PVSSFLSI 413
Query: 364 RNQT 367
T
Sbjct: 414 NGDT 417
Score = 64.9 bits (151), Expect = 2e-08
Identities = 41/132 (31%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + Y L ++ LF++DS G + + DL L + + +
Sbjct: 3329 VSAADGDTGSNGEVTYSLSQSSESFSGLFNIDSNTGDITVNVTDDLLDREML--SEYNIT 3386
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A+ +P + + +++ D+NDN P FE Y I+EN G SVL V A D+D
Sbjct: 3387 VTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLSVKAHDRDS 3446
Query: 336 GENGEFTYQLDD 347
G N +Y L+D
Sbjct: 3447 GNNARISYFLED 3458
Score = 64.5 bits (150), Expect = 2e-08
Identities = 60/224 (26%), Positives = 101/224 (45%), Gaps = 26/224 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN G++++K++A D D+G NG++ Y LS + F I+ G
Sbjct: 3316 IPENFSKGSSVLKVSAADGDTGSNGEVTYS-----------LSQSSESFSGLFNIDSNTG 3364
Query: 1000 HVIVARS---LPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ V + L E SE+ + ++A D G+ + N ++ + + DVND+ PVF++ Y
Sbjct: 3365 DITVNVTDDLLDREMLSEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTA 3424
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL---- 1108
+ E + V A D D G NA ++YF++ + S V + +GE+
Sbjct: 3425 FIMENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVN-GVSASTFISVHAESGEILAAR 3483
Query: 1109 --DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
D E + + V A+D G D NDN+P+
Sbjct: 3484 SFDYEQTKDFSIRVKAQDGG-SPPLSSNVSVKILIQDQNDNAPQ 3526
Score = 62.5 bits (145), Expect = 9e-08
Identities = 165/714 (23%), Positives = 280/714 (39%), Gaps = 89/714 (12%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + Y +S D+ LFSL+ G + + +D + + + VL
Sbjct: 65 VSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYELR--VLA 122
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A+ L T+ + V I++ D NDN P NI I E+ G V + D+D
Sbjct: 123 KDAAGL-----TSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDS 177
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-KETNPSVVGTF 394
NG+ + + + ++ LDRE S + + A E +P + T
Sbjct: 178 ENNGQVRCSIQQNVPFKLVPSIKNYYSLVTTGELDRELLSEYNITITATDEGSPPLSSTK 237
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
+A P + K + V T + D N EVT +
Sbjct: 238 NIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDAD--EGQNGEVTYEFGHI 295
Query: 455 NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKIN 514
+ +++ FS+ N+ T+IG + D +Q T L + S +
Sbjct: 296 SE-----NDITIFSLDQNSGKITLIGSL-----DYEDEASFDLPIQATDGLGLVSYSTVV 345
Query: 515 PNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR--GTKGNKPDIPD 572
+ V+ P+ + ++ A Q N + S T R GT D
Sbjct: 346 IDVSDVN-DNPPVFQQQN---YRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSD 401
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVV 632
GAP ++ N G + +R D +EQ L+ + G P S +TV+
Sbjct: 402 VNGAPVSSFLSINGDTGV-IHAVRSFD-YEQMKSFKVLVLARDNGSPPLSSNVSIHVTVL 459
Query: 633 DDLSRYNRPMYD--FEAVALQENANLSIVTNATVHVVDVNDERG--VLLKGAH----SPI 684
D + N P++ V+L EN+ + V TV D ++ + V + H
Sbjct: 460 D--ANDNAPVFSQAVYKVSLPENSPVDTVV-VTVSATDADEGQNGEVTYEFGHIMEDYKH 516
Query: 685 IFHVKENSAGAAI-GQI-------FHTNMSSIYGNGTGNVRFLIANQQDVTDD----IAI 732
+F++ + +I G + F + + G+G + ++ + DV D+ I +
Sbjct: 517 LFNLDRKTGVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSNVLISVSDVNDNSPIIIPL 576
Query: 733 AE-------DGTIFT-QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
E G + T +KPLDRE + + +T ++ + G S +G + I++ D NDN
Sbjct: 577 TETPGSFMPSGRLITSRKPLDRESKADHFLT-LSGVDGGRPSRSGTASIHIHVLDANDNI 635
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDE 841
PV G ++ +K++ ATD D G Y+ + + + +VD
Sbjct: 636 PV-------GSVL--------VKLN----ATDLDSGIYGAVSYSFSHVPDKTRGILEVDS 676
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
TG V+ + LDREK Y +++ A D G L S + I + D NDN P F
Sbjct: 677 VTGEVRIM---LDREKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIF 727
Score = 60.9 bits (141), Expect = 3e-07
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 12/167 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + + Y + + ++ + S+ S + +EL H + +L
Sbjct: 2364 VSATDADEGINSKIEYSIANIDNGQSVSIQS-----YYSRELGKG--HRVDHKN-ILYKN 2415
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + A++ I +LD NDN P F Y SI EN G + V A+D D+G
Sbjct: 2416 AIDGGDPQLSGTAQIHITVLDANDNAPVFTQKIYKASITENAVRGTVITTVSASDLDEGS 2475
Query: 338 NGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
G+ TY LDD F I+ +G + V ++ H + ++
Sbjct: 2476 YGKITYAITNTLDDVPVLFEINETNGEVRVIGTVDYEKARHYQIHVQ 2522
Score = 60.5 bits (140), Expect = 3e-07
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 3/133 (2%)
Query: 218 IHAIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA-NTFVL 274
+ A D D G + Y SG + LF + + G + L D + + + + +
Sbjct: 3108 VSATDNDQGANGEITYSFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREKISEYNI 3167
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A+ +P + + +++ D+NDN P FE Y I+EN G SVL V A D+D
Sbjct: 3168 TVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLSVKAHDRD 3227
Query: 335 QGENGEFTYQLDD 347
G N +Y L+D
Sbjct: 3228 SGNNARISYFLED 3240
Score = 52.8 bits (121), Expect = 7e-05
Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ V A+ P T++ ++++D+NDN P F YN + EN G S+L++ A D
Sbjct: 1441 ITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNSPGVSILRIRAHDP 1500
Query: 334 DQGENGEFTYQLDDPK-GAF-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+ +N +Y L++ G + S++ SG V D E ++++ V A++
Sbjct: 1501 DENQNARISYILEESDLGTYVSVNAESG--VVHAVRSFDYEQIKNIKVTVKAQD 1552
Score = 52.0 bits (119), Expect = 1e-04
Identities = 75/322 (23%), Positives = 137/322 (42%), Gaps = 38/322 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRG--L 138
+ + + DVNDN P+ T + + E +P G + + + G + + L + +
Sbjct: 925 LVIDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSSPF 984
Query: 139 TIFKDIRAF-----DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA- 192
TI R + D S + ++V+ D+G +L S L + + D
Sbjct: 985 TIKPSPRKYYTLVTDAPLDREKVSSFNLTLVA-TDEGSPSLFSKITISLDVTDINDNAPV 1043
Query: 193 -GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR-----KLFSL 246
+E++ +M + +L + A D D G A + Y LI + FS+
Sbjct: 1044 FSQREYKAYVMENNSP-GVSLL---TLQASDPDAGQNARIAYYLIDSDVNGSPVSSHFSV 1099
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE- 305
++ NG + + D + Q F + V+A +P + A V I + D NDN P+
Sbjct: 1100 NADNGIIHAVRSFDYE-----QMKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDNAPQV 1154
Query: 306 -FEVDFYNISIVENLPN----GFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRS 358
+ V + E +P G+ V +V+A D D G+N +Y+L + F + ++
Sbjct: 1155 LYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQN 1214
Query: 359 GWL-TVRNQTVLDREAHSSLRM 379
G + TVR ++ D H SL++
Sbjct: 1215 GEIRTVRQESADD---HDSLKL 1233
Score = 50.4 bits (115), Expect = 4e-04
Identities = 36/171 (21%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 218 IHAIDQDLGVGATLRYELIS--GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
++A D D G + Y G +LF++DS G + + E+D + + F L
Sbjct: 1285 VNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNTGIISVVGEIDHEKD-----TKFELT 1339
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A T +++ ++++D+NDN P ++ ++ E+ P ++ + D D
Sbjct: 1340 VEARDQGG--LTDSSKITLDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAIINVKDADT 1397
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+NG + ++ + + ++ +LDRE S + V A ++
Sbjct: 1398 DDNGRVSCFIEGSEDFVVKSTLRNYYSLVTNVILDREKLSEYNITVVATDS 1448
Score = 45.2 bits (102), Expect = 0.014
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 37 AQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVR----IGAGLNQISAYLSVTVYIEDVND 92
A + + DS VVK G D+++ L+ + G Q+S + + + + DVND
Sbjct: 2278 ADKAADIFEIDSELGVVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVND 2337
Query: 93 NVPIFLDTPYHVTVDELTP 111
N P+F+ + Y TV E P
Sbjct: 2338 NAPVFMQSVYKATVTENAP 2356
Score = 39.9 bits (89), Expect = 0.53
Identities = 71/311 (22%), Positives = 128/311 (41%), Gaps = 46/311 (14%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG------------- 113
+V +G +++ + + + DVNDN P+F + Y+ + E G
Sbjct: 1443 VVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNSPGVSILRIRAHDPDE 1502
Query: 114 -EKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF 172
+ A I I L ++V + +R+FD ++ N V V D G
Sbjct: 1503 NQNARISYILEES-DLGTYVSVNAESGVVHAVRSFDYEQ--IKNIKV---TVKAQDGGSP 1556
Query: 173 ALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGA-- 229
L S+ V + VLD + F Q V AS + + ++A D D G
Sbjct: 1557 PLSSN---VTIDVTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHI 1613
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
TL + + R +F++D G + + +D + + F ++V+A+ T+
Sbjct: 1614 TLSFSDLKEQSRGIFNIDENTGLVSVLGNIDFEKDKR-----FEIRVKATDQGG--LTST 1666
Query: 290 ARVEIELLDLNDNLPEFEVDFYN--IS-----------IVENLPNGFSVLQVMATDKDQG 336
+++ IE++D+NDN P + + +S ++EN G S+ V A D D
Sbjct: 1667 SKLIIEVVDVNDNAPVITLMSLSSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDLDWN 1726
Query: 337 ENGEFTYQLDD 347
+N +Y L+D
Sbjct: 1727 QNSRVSYYLED 1737
Score = 37.9 bits (84), Expect = 2.1
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 5/87 (5%)
Query: 32 VSVILAQS-IDSLVDSDSPQNVVKFRLGCDFDEGDDL-VRIGA---GLNQISAYLSVTVY 86
+S IL +S + + V ++ VV D+++ ++ V + A G +S+ +++ V
Sbjct: 1508 ISYILEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVT 1567
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ DVNDN P+F T Y +V E P G
Sbjct: 1568 VLDVNDNAPVFNQTVYRASVTENAPKG 1594
Score = 35.9 bits (79), Expect = 8.6
Identities = 17/47 (36%), Positives = 24/47 (51%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
L+ + G Q S + + V + D NDN P+F T Y +V E P G
Sbjct: 1233 LIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQTVYRASVMENAPKG 1279
>UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenopus
tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
Length = 3555
Score = 200 bits (489), Expect = 2e-49
Identities = 231/938 (24%), Positives = 401/938 (42%), Gaps = 118/938 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
LMSF V + DANDN PVF ++Y+ ++ N V + + V A D D G N + Y
Sbjct: 1921 LMSF---RVVITDANDNFPVF-SKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYS 1976
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
+ S TSPF I+ +TG + +++P+ E H L + A D NP + A++
Sbjct: 1977 FIQLSE---TSPFTISQHTGEIRTSQAPLDRETESIHELVLTAFDG-GNPVQT--GTAII 2030
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHG 613
I V+ + P F Y + N+ + +++ ++ ND E + ++Y
Sbjct: 2031 KIIVS----DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAAS 2086
Query: 614 YEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
++ + F ++ SG + ++L Y+ +V ++ L + ++D ND
Sbjct: 2087 SKQAMNTFIIDSISGEVKTKENLDFEKIKHYEI-SVQAKDGGGLVSHAKILIQIIDFNDN 2145
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR--FLIANQQDVTDDI 730
V S ++ V N I + + + +R F +++Q + I
Sbjct: 2146 LPVF-----SQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFI 2200
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G I T++ LD EK +Y ++V A+ G++S A + T+ + D NDNPPVF++
Sbjct: 2201 INSISGAIMTKENLDFEKTKLYEISVQAKDGGGLVSHAKVLIQTLDVSDINDNPPVFKYP 2260
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDEN--TG 844
Y +I EN++ G I I+A D D NA +Y++ GE + N TG
Sbjct: 2261 NYLAYIPENNQPGASIYS---IQAIDNDSEENAKLIYSIINMNTGEPSPSSYISINPVTG 2317
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
V+ + S D E+ +++ ++A+D G L+S + I + D+ND NS +
Sbjct: 2318 VI-YAQRSFDYEQDREFQIQIMAKDNGSPPLNSSVIVTICVTDQND----------NSPL 2366
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
++ G+A + ++P + GT + K+ A+D DSG
Sbjct: 2367 VLYPSADAGGSAAYE---------------------MVPFSSEQGTLVTKVVAVDADSGH 2405
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISAL 1020
N + Y F + S+ S YFVI++ + +++ SL E+E + + ++A
Sbjct: 2406 NAWLSYHF-----LQDSETS--------YFVIDQ-YTELVLKTSLDRENENFYEIVLTAF 2451
Query: 1021 DGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
DGGN +R+ V D ND+FP+F + Y ++ E + V A+D D G N+
Sbjct: 2452 DGGNPMQTGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINS 2511
Query: 1079 NLTYFIQPSDTDL--PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
LTY + F I+P +G + LD E Y + V A+D G
Sbjct: 2512 QLTYSFSSASKQATNAFAINPQSGEVITKDILDFEKMKNYEIAVQAKDGG---GLISHAK 2568
Query: 1137 XXXXXXDVNDNSPKFYAFDELLEWKHPEADE---------LSNHNFESVMMIPVYKATIE 1187
D NDN P+ L +P ++E ++N E + Y +
Sbjct: 2569 VLIQILDENDNPPEV----SLTSITNPVSEESAPGTVVALIANDKDEGINAQITYSFSAT 2624
Query: 1188 ENAPIGTTVAKVFANDTDFIGN--GNGLILYSLP-QRKNQQNLGLPSLSSTAILMVTVAD 1244
+ + + N Y + Q + + G P + TA++ +TV D
Sbjct: 2625 SKQASRSFAINAISGEIKTKENIDFEKTKYYEISVQARISFDGGSPMQTGTALIRITVTD 2684
Query: 1245 VPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDI 1302
+ D P+F Y + I EN+ N+ V VS N + N ++ Y +
Sbjct: 2685 MNDNF-----PIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQIT-YSFSATSKQA 2738
Query: 1303 RRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
R+F I+ G + + D E YE+ V+A+ QK+
Sbjct: 2739 SRSFSINSETGEIKTKENLDFEKTKNYEISVQAKIQKH 2776
Score = 171 bits (415), Expect = 2e-40
Identities = 207/886 (23%), Positives = 369/886 (41%), Gaps = 86/886 (9%)
Query: 50 QNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDEL 109
+ V +F++ +G + VR G L +I+ + D NDN+P+F Y V++ E
Sbjct: 326 EQVKEFQIQITASDGGNPVRSGTALIRIA--------VTDSNDNLPVFTQEVYKVSISEN 377
Query: 110 TPTGEKAFIFLIAPI--GPSLTIPLTVPR--GLTIFKDIRAFD------RDKPNTP-NSD 158
P G + I + + G + + + + + K N +
Sbjct: 378 IPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFEAK 437
Query: 159 VHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEP 217
Y I V D G F +H +L+ K++ D D + + + E
Sbjct: 438 KFYEISVQAKDGGGFV---AHSKILI--KLIKLDISDVNDNAPVFTKSSYVSMVPVASEQ 492
Query: 218 ------IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT 271
+ A+D D G A L Y ++ G++ LFS+ G + + D + Q
Sbjct: 493 GALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSRVFQ-DKDRETQT-I 550
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI-----VENLPNGFSVL 326
L + AS NP+++ A + I + D NDNLP F + Y +SI + + + S +
Sbjct: 551 HELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISTLIALIEVHDQDSDI 610
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-LDREAHSSLRMKVYAKE 385
+++ D + + + + +G R Q +D ++ + +Y +
Sbjct: 611 KLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTD 670
Query: 386 TNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNV 445
T + +F L PL++ T + + T ++ + +
Sbjct: 671 TEDYSMSSFFS----INIETGVLYAQKPLDRETQSIHELILTASDG---GNPLRTGTALI 723
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS-N 504
+ + D+NDN PVF +Y+ S+ NA + + + + A D D G N + Y + +TS N
Sbjct: 724 RIIVTDSNDNLPVFT-QEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSEN 782
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
TS F INP G +++ E P+ + H L + ASD +P + A++ I VT
Sbjct: 783 NFYTSVFNINPVMGEITIKEKPLDRETQKDHELILTASDG-GDPVKT--GTAIIRIIVTD 839
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
++P F A Y+ + N+ I +SV + D E + ++Y + E +
Sbjct: 840 AND----NLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSENDIH 895
Query: 620 ---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG-V 675
F++ + +G I + L Y+ +V + + + +++ ND +
Sbjct: 896 SPMFSINQINGEIKTLQKLDFELTRNYEM-SVQATDGGGFVAHSKVLLEIINENDNAPEI 954
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQI-FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ +PI +++ G I I H + S NG L + + +
Sbjct: 955 TMTSVSTPI---PEDSEPGTVIALIKVHDHDSG--ENGEAECHLLGSPPFQLVS--TSSS 1007
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
I T LDREK +Y +T++A +KG + + + I D NDNPPVF + Y
Sbjct: 1008 YYRIITTSVLDREKVQLYNITILAN-DKGSPQLSSRKSILLDISDVNDNPPVFLKSRYIA 1066
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE------NTGVVKF 848
++ EN+ G I ++A+D D G N+ +Y++F E F V TGV+ +
Sbjct: 1067 YLPENNLPGASIYK---VQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVL-Y 1122
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE 892
S D E+ + + + A+D G LSS A LII I D+NDN P+
Sbjct: 1123 AQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPK 1168
Score = 155 bits (376), Expect = 9e-36
Identities = 188/733 (25%), Positives = 309/733 (42%), Gaps = 86/733 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
++S +N+++T+ D NDN PVF +Y+ ++ N + + + +V A D D G N + Y
Sbjct: 2778 ILSLINIQITVTDFNDNFPVFT-QEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYS 2836
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
T+ + F INP +G ++ + ++ + + S Q A S A V I+
Sbjct: 2837 FGTTAT-NVLRIFAINPKSGEITTKGN--VDFEETKYYDISVQ-AQDGGSLASHAKVLIQ 2892
Query: 559 VTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYE 615
+ N P+I + P V + GT V I+ + D+ E +V +++ G
Sbjct: 2893 IL-DENDNAPEISVTSITTP----VSEDSPTGTVVALIKAHDLDSGENGEVDCEIV-GV- 2945
Query: 616 EGVPFAVEERSG---VITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
+PF + SG I L R P Y+ + + LS + + ++D+ND
Sbjct: 2946 --IPFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHTTDKGSPTLSSLKTIRLDILDIND 3003
Query: 672 ERGVLLKGAHSPIIFHVKENSAGA------AIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
K + + + + N GA AI + N +Y T N +
Sbjct: 3004 NPPKFEKSNY--VAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTEKFPSFSYI 3061
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ + E + T LDRE + + + + A + G + I + D NDN P
Sbjct: 3062 SINSVTGGEKKS--TDTSLDRETQSNHELILTASDGGNPVQ-TGTTLIKITVTDFNDNFP 3118
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY---TLFGEGKEMFDVDEN 842
VF Y+ I EN I + + + A+D D G NA Y T +F ++ N
Sbjct: 3119 VFTQEVYKVNIHENIPINSTVLR---VNASDKDAGINAQVTYSFSTSANNVHRIFSINPN 3175
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENS 900
G + +LDREK Y +++ A D G LSS+ + + + D NDN P+F E+++
Sbjct: 3176 NGEITTKASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKF---EKSN 3232
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
V E N G +I +K +K D ++ G + N + + + +++ +
Sbjct: 3233 YVAYVTE---NNQPGSSIFSIKAIDK---DTEENGKVVYSISNNTVEFSSVSYISINPVT 3286
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL 1020
G + Y S Y E R F+I I+A+ S LN SA+
Sbjct: 3287 G----VIYALQSFDY-----------EQDREFLIQ------IMAKDSGSPS---LNSSAI 3322
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
NI+V F ND+FPVF + Y N+ E + V+A+D D G NA +
Sbjct: 3323 ------VNITVTDF----NDNFPVFTQEVYKVNIHENIPINSTVLHVNASDKDEGINAQI 3372
Query: 1081 TYFIQPSDTDL--PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
TY + ++ F I+P G + + G LDRE Y +T+ A D G
Sbjct: 3373 TYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQATDKG-SPPLSSWKTIA 3431
Query: 1139 XXXXDVNDNSPKF 1151
D+NDNSP F
Sbjct: 3432 LEVLDINDNSPVF 3444
Score = 150 bits (363), Expect = 3e-34
Identities = 233/947 (24%), Positives = 386/947 (40%), Gaps = 129/947 (13%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L S + + +LD NDN P+F+ S +Y + N G I ++ A+D D+G N V+Y
Sbjct: 1364 ELSSRKFIRLDILDVNDNPPIFIKS-VYNVYLPENNLPGASIYRIHALDLDMGDNAKVIY 1422
Query: 498 DLQRTS--NLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLA 553
+ T+ + ++S F IN TG + S + + + ASD + R A
Sbjct: 1423 SISNTNTEDFPVSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASD---GGTPVRTGTA 1479
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
++ + VT + P F Y+ + N I ++V ++ +D E + ++Y
Sbjct: 1480 LIRVIVTDA----NDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFS 1535
Query: 612 HGYEEGV---PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV- 667
+ F++ SG IT L R + ++ A + N A + ++
Sbjct: 1536 RTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTA-SDGGNPVRTGTALIQIIV 1594
Query: 668 -DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND V + ++ + EN+A ++ + N SS + + I+ +
Sbjct: 1595 TDANDNLPVFTEVLYT---VSISENTAVGSV--VLCVNASS-----NAKITYSISETNTM 1644
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI------ED 779
+ +I E G ++ Q+ D E+ + M ++A+ N G S + I+I D
Sbjct: 1645 SPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDN-GFPSMTSNTTLLIHIIDRVVVTD 1703
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNI--------IKATDADEGTNALFMYTLFG 831
NDN PVF Y I EN+ + + N + ATD DEGTNA Y+
Sbjct: 1704 ANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDEVLHVNATDRDEGTNAQITYSFIK 1763
Query: 832 EG-KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--------LSSEAELIIM 882
F ++ TGV+ + S D E+ + + + A+D G LSS + +
Sbjct: 1764 TSVSSYFSINIETGVL-YAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLD 1822
Query: 883 IGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPE 942
I D NDN P F + + + E L G + +T+ A DVD +
Sbjct: 1823 ISDVNDNPPVFRKSLYTTYL---PENNLPGASIYTV--------HATDVDS-------GD 1864
Query: 943 NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY--FVINERHGH 1000
N + +I N D + N E + ++ S D + K + + R GH
Sbjct: 1865 NAKLIYSISNANTEDFPV----SSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRSGH 1920
Query: 1001 VIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
++ FR+ I+ + NDN VF KDV Y V E
Sbjct: 1921 LM---------SFRVVIT-----DANDNFP--VFSKDV-----------YKTTVNENMPV 1953
Query: 1061 RRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTG-VLSVNGELDRETEDKYIL 1118
+ V A+D D G NA +TY FIQ S+T PF IS TG + + LDRETE + L
Sbjct: 1954 NSTVISVTASDKDEGTNAQITYSFIQLSETS-PFTISQHTGEIRTSQAPLDRETESIHEL 2012
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF------YAFDELLEWKHPEADELSNHN 1172
+ A D G D NDN+P F + +E + +N
Sbjct: 2013 VLTAFDGG-NPVQTGTAIIKIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDK 2071
Query: 1173 FE-SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
E S I Y A + A + T + + + N + + ++ G
Sbjct: 2072 DEGSNSQITYYFAASSKQA-MNTFIIDSISGEVKTKENLDFEKIKHYEISVQAKDGG--G 2128
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFK 1289
L S A +++ + D D + PVF Y++ I EN +N+ + VS N + N +
Sbjct: 2129 LVSHAKILIQIIDFNDNL-----PVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQ 2183
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+RYY + + I TF+I+ +G + + D E YE+ V+A+
Sbjct: 2184 IRYY-FSTSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQAK 2229
Score = 144 bits (350), Expect = 1e-32
Identities = 211/863 (24%), Positives = 358/863 (41%), Gaps = 81/863 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG---------EKAFIFLIAP 123
G Q+S + + I DVNDN P+F+ + Y ++ E +P +K IA
Sbjct: 236 GSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVKHQKIAF 295
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
I + P++ + I + R + I + + ++ + +
Sbjct: 296 IMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAV 355
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL--ISGND- 240
+ +E V ++ I+ +L ++A D+D G A + Y SGN+
Sbjct: 356 TDSNDNLPVFTQEVYKVSISENIPINSTVL---TVNATDRDEGTNAQIMYSFSKTSGNNL 412
Query: 241 -RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL---KTAQARVEIEL 296
+FS++ +G + ++ + +A+ + + VQA + K +++++
Sbjct: 413 HTSMFSINYTSGEIKTKQNFNFEAK-----KFYEISVQAKDGGGFVAHSKILIKLIKLDI 467
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
D+NDN P F Y + G + +V+A D D G N +Y + FSI
Sbjct: 468 SDVNDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSI 527
Query: 355 DPRSGWL-TVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIAKWRRQPLETNA 412
+G + T R DRE + + + A + NP GT RIA N
Sbjct: 528 SQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTAL--IRIAV---TDANDNL 582
Query: 413 PLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN 472
P+ T V+ + T IE +D+ +++ + D NDN PVF S+ + ++N
Sbjct: 583 PV-FTQEVYKVSISTLIALIEVHDQD-SDIKLIKLDISDVNDNAPVFTKSSYVAYIAENN 640
Query: 473 AKVGTVIGKVKAVDPDLGQNGMVLYDLQR--TSNLTITSPFKINPNTGTVSVAESPI--- 527
G I +++A D D G N ++Y + T + +++S F IN TG V A+ P+
Sbjct: 641 L-AGASIYRIQASDIDAGDNAKIIYSIYNTDTEDYSMSSFFSINIETG-VLYAQKPLDRE 698
Query: 528 LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG 587
+ H L + ASD NP R A++ I VT + ++P F Y+ + N
Sbjct: 699 TQSIHELILTASD-GGNP--LRTGTALIRIIVT----DSNDNLPVFTQEVYKVSISENAP 751
Query: 588 IGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV---PFAVEERSGVITVVD-DLSRYNRP 641
I +SV + D E + ++Y + E F + G IT+ + L R +
Sbjct: 752 INSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKEKPLDRETQK 811
Query: 642 MYDFEAVALQENANLSIVTNAT---VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
D E + + + T + V D ND V K + + EN
Sbjct: 812 --DHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYK---VSISENI--PINS 864
Query: 699 QIFHTNMSSIYGNGTG---NVRFLIANQQDVTDDI-AIAE-DGTIFTQKPLDREKRDVYR 753
+ H N + GT F+ ++ D+ + +I + +G I T + LD E Y
Sbjct: 865 SVLHVNATD-RDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYE 923
Query: 754 MTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
M+V A G ++ + +V + I +ENDN P + I E+S+ GT I +IK
Sbjct: 924 MSVQATDGGGFVAHS---KVLLEIINENDNAPEITMTSVSTPIPEDSEPGTVIA---LIK 977
Query: 814 ATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS-LDREKKIMYKLSLVARDTGG 872
D D G N L G V ++ + I S LDREK +Y ++++A D G
Sbjct: 978 VHDHDSGENGEAECHLLGSPPFQL-VSTSSSYYRIITTSVLDREKVQLYNITILANDKGS 1036
Query: 873 --LSSEAELIIMIGDENDNKPEF 893
LSS +++ I D NDN P F
Sbjct: 1037 PQLSSRKSILLDISDVNDNPPVF 1059
Score = 142 bits (344), Expect = 7e-32
Identities = 240/992 (24%), Positives = 397/992 (40%), Gaps = 118/992 (11%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
M F+ ++++ D NDN P+FV S +Y+ S+ N+ V T + V A D Q + D
Sbjct: 243 MKFIKLDIS--DVNDNPPMFVKS-VYKASISENSPVNTTVLYVNATDKVKHQKIAFIMD- 298
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTI 557
+ I+S F IN TG + S E + + ASD NP R A++ I
Sbjct: 299 --NEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDG-GNPV--RSGTALIRI 353
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV----SYDLLHG 613
VT + ++P F Y+ + N+ I ++V + D E + S+ G
Sbjct: 354 AVT----DSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSG 409
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS----IVTNATVHVVD 668
F++ SG I + + + Y+ A ++ ++ + + D
Sbjct: 410 NNLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISD 469
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
VND V K ++ ++ E GA I ++ + S G+ ++ +
Sbjct: 470 VNDNAPVFTKSSYVSMVPVASEQ--GALITKVVAVDADS--GHNAWLSYHVVQGSEPSLF 525
Query: 729 DIAIAEDGTIFTQKPL---DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I+ G I T + DRE + ++ + + A + +G + I + D NDN P
Sbjct: 526 SIS-QNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVR-SGTALIRIAVTDANDNLP 583
Query: 786 VFEHATYEGFIMENSKIGTEIKMDN---IIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
VF Y+ I + D+ +IK +D NA +F + + + EN
Sbjct: 584 VFTQEVYKVSISTLIALIEVHDQDSDIKLIKLDISDVNDNA----PVFTKSSYVAYIAEN 639
Query: 843 T----GVVKFIGDSLDR--EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP---EF 893
+ + +D KI+Y + + +SS + I G KP E
Sbjct: 640 NLAGASIYRIQASDIDAGDNAKIIYSIYNTDTEDYSMSSFFSINIETGVLYAQKPLDRET 699
Query: 894 NQIEENSKVRIHRETKLN-GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
I E L GTA II + + ++ + I EN PI +++I
Sbjct: 700 QSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVS-ISENAPINSSVII 758
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA-RSLPPES 1011
L A D D G N QI Y SK S + F IN G + + + L E+
Sbjct: 759 LTATDKDEGTNAQITYSI--------SKTSENNFYTS-VFNINPVMGEITIKEKPLDRET 809
Query: 1012 E--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ L ++A DGG+ +R+ V D ND+ PVF K Y ++ E + V
Sbjct: 810 QKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHV 869
Query: 1068 DATDADFGQNANLTY-FIQPSDTDLP---FEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
+ATD D G NA +TY FI+ S+ D+ F I+ + G + +LD E Y ++V A
Sbjct: 870 NATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQAT 929
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D G + NDN+P+ + PE E + +I V+
Sbjct: 930 DGGGFVAHSKVLLEII---NENDNAPEITMTS--VSTPIPEDSEPGT----VIALIKVHD 980
Query: 1184 ATIEENAP------------IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
EN + +T + + T + + + LY++ N + G P
Sbjct: 981 HDSGENGEAECHLLGSPPFQLVSTSSSYYRIITTSVLDREKVQLYNITILANDK--GSPQ 1038
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFI-SRYYELEIEENV-NAPVELVSLNLTEHYENFK 1289
LSS +++ ++DV D + PVF+ SRY E N+ A + V + + EN K
Sbjct: 1039 LSSRKSILLDISDVND-----NPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSK 1093
Query: 1290 MRYYILNENDT--DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
+ Y + N N + F I+ G LY RS D E + + V+A+ Y P +
Sbjct: 1094 VIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGY----PSL 1149
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
+ +++RI D NDN+PK
Sbjct: 1150 -------------SSNATLIIRIIDQNDNAPK 1168
Score = 138 bits (333), Expect = 1e-30
Identities = 185/736 (25%), Positives = 305/736 (41%), Gaps = 91/736 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + +LD NDN P +++ + ++ GTV+ +KA D D G+NG V +
Sbjct: 2883 LASHAKVLIQILDENDNAPEISVTSITT-PVSEDSPTGTVVALIKAHDLDSGENGEVDCE 2941
Query: 499 LQRTSNLTITSP----FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
+ + S +KI T T+ ++P R+ L + +D+ S SL
Sbjct: 2942 IVGVIPFKLLSSSGNFYKII-TTSTLDREKTP----RYNLTIHTTDKG---SPTLSSLKT 2993
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH 612
+ +++ + P P F + Y +V N G S+ I+ D E V Y +
Sbjct: 2994 IRLDIL--DINDNP--PKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFT 3049
Query: 613 GYEEGVP----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT---VH 665
E P ++ +G D S + E + + + T T +
Sbjct: 3050 NNTEKFPSFSYISINSVTGGEKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKIT 3109
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V D ND V + + ++ EN + N S V + + +
Sbjct: 3110 VTDFNDNFPVFTQEVYK---VNIHENIP--INSTVLRVNASDKDAGINAQVTYSFSTSAN 3164
Query: 726 VTDDIAIAE--DGTIFTQ-KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
I +G I T+ LDREK Y +T+ A +KG + + + + D ND
Sbjct: 3165 NVHRIFSINPNNGEITTKASTLDREKTPHYNITIQAT-DKGSPPLSSKKTIRLDVSDIND 3223
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
NPP FE + Y ++ EN++ G+ I IKA D D N +Y++ E V
Sbjct: 3224 NPPKFEKSNYVAYVTENNQPGSSIFS---IKAIDKDTEENGKVVYSISNNTVEFSSVS-- 3278
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+I S++ ++Y L + + E +I I ++ P N ++ V
Sbjct: 3279 -----YI--SINPVTGVIYALQ-----SFDYEQDREFLIQIMAKDSGSPSLNS---SAIV 3323
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
I T + F + F +V ++ I ENIPI +T++ +NA D D G+
Sbjct: 3324 NI---TVTDFNDNFPV--------FTQEVYKVN----IHENIPINSTVLHVNASDKDEGI 3368
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISAL 1020
N QI Y F S SA+ L R F IN ++G + + +L E S + + I A
Sbjct: 3369 NAQITYSF--------STTSANVL---RMFYINPQNGEIKIKGTLDRERSSHYNITIQAT 3417
Query: 1021 DGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
D G+ L+ ++ + V D+ND+ PVF+K+ Y V E + + A D D +N
Sbjct: 3418 DKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEENG 3477
Query: 1079 NLTYFIQPSDTD-----LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
L Y I S+T+ I+P+TGV+ D E + ++ + ++A+DNG
Sbjct: 3478 KLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQIIAKDNG-SPPLNS 3536
Query: 1134 XXXXXXXXXDVNDNSP 1149
D NDNSP
Sbjct: 3537 STIVRICVVDQNDNSP 3552
Score = 136 bits (329), Expect = 4e-30
Identities = 165/739 (22%), Positives = 302/739 (40%), Gaps = 47/739 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L++ V + ++D NDN P ++L + ++ GT+I ++ D D G+NG
Sbjct: 130 LLAQSKVLIEIIDENDNAPEISIASL-STPIPEDSAPGTLIALIEVHDQDSGENGEAECH 188
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ +S +K ++ + + L+ + + + + S + I+
Sbjct: 189 ILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLS-TMKFIK 247
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH-GYEEG 617
+ + P P F+ + Y+ + N + T+V + D + +++ + + +
Sbjct: 248 LDISDVNDNP--PMFVKSVYKASISENSPVNTTVLYVNATDKVKHQKIAFIMDNEDFPIS 305
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVL 676
F++ +GV+ + + A N S + V D ND V
Sbjct: 306 SYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDSNDNLPVF 365
Query: 677 LKGAHSPIIF-HVKENSAGAAIGQIFH---TNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + I ++ NS + TN +Y + L + +
Sbjct: 366 TQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSIN----- 420
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY--QVTIYIEDENDNPPVFEHA 790
G I T++ + E + Y ++V A+ G ++ + I + + I D NDN PVF +
Sbjct: 421 YTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFTKS 480
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKF- 848
+Y + S+ G I + A DAD G NA Y + G +F + +NTG ++
Sbjct: 481 SYVSMVPVASEQGALITK---VVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTS 537
Query: 849 -IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ----IEENSK 901
+ DRE + +++L L A D G S A + I + D NDN P F Q + ++
Sbjct: 538 RVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISTL 597
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
+ + + +++ N A + + I EN G +I ++ A D+D+G
Sbjct: 598 IALIEVHDQDSDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAG 657
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISA 1019
N +I Y +Y + + +F IN G + + L E++ L ++A
Sbjct: 658 DNAKIIYS----IY----NTDTEDYSMSSFFSINIETGVLYAQKPLDRETQSIHELILTA 709
Query: 1020 LDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
DGGN +R+ V D ND+ PVF + Y ++ E + + ATD D G N
Sbjct: 710 SDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTN 769
Query: 1078 ANLTYFIQPSDTD----LPFEISPLTGVLSVNGE-LDRETEDKYILTVVARDNGXXXXXX 1132
A +TY I + + F I+P+ G +++ + LDRET+ + L + A D G
Sbjct: 770 AQITYSISKTSENNFYTSVFNINPVMGEITIKEKPLDRETQKDHELILTASDGG-DPVKT 828
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D NDN P F
Sbjct: 829 GTAIIRIIVTDANDNLPVF 847
Score = 128 bits (308), Expect = 2e-27
Identities = 132/484 (27%), Positives = 210/484 (43%), Gaps = 38/484 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +T+ D NDN P+F +Y S+ N + + + V A D D G N + Y TS
Sbjct: 2678 IRITVTDMNDNFPIF-GQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSK 2736
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
S F IN TG + E+ L+ E S Q ++ + L+++ I++T T
Sbjct: 2737 QASRS-FSINSETGEIKTKEN--LDFEKTKNYEISVQAK--IQKHHILSLINIQITV-TD 2790
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP---FA 621
N + P F Y+ + N+ I ++V Q+ +D E + G FA
Sbjct: 2791 FND-NFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFA 2849
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ +SG IT ++ YD +V Q+ +L+ + ++D ND + +
Sbjct: 2850 INPKSGEITTKGNVDFEETKYYDI-SVQAQDGGSLASHAKVLIQILDENDNAPEI---SV 2905
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT---I 738
+ I V E+S + + + NG + + V ++ G I
Sbjct: 2906 TSITTPVSEDSPTGTVVALIKAHDLDSGENGEVDCEIV-----GVIPFKLLSSSGNFYKI 2960
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LDREK Y +T+ +KG + + + + + I D NDNPP FE + Y ++ E
Sbjct: 2961 ITTSTLDREKTPRYNLTIHTT-DKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTE 3019
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF------DVDENTGVVKFIGD- 851
N++ G I I+A D D N +Y++F E F ++ TG K D
Sbjct: 3020 NNQPGASIYS---IQAIDEDTEENGKVVYSIFTNNTEKFPSFSYISINSVTGGEKKSTDT 3076
Query: 852 SLDREKKIMYKLSLVARDTGG-LSSEAELI-IMIGDENDNKPEFNQIEENSKVRIHRETK 909
SLDRE + ++L L A D G + + LI I + D NDN P F Q E KV IH
Sbjct: 3077 SLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQ--EVYKVNIHENIP 3134
Query: 910 LNGT 913
+N T
Sbjct: 3135 INST 3138
Score = 117 bits (281), Expect = 3e-24
Identities = 125/491 (25%), Positives = 210/491 (42%), Gaps = 56/491 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
+ + + D NDN PVF +Y+ S+ +A + + + V A D D G NG + Y RT+
Sbjct: 29 LRIIVTDYNDNVPVFT-QQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAE 87
Query: 504 NLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
N T F INP G + E + + V+A D ++ + V IE+
Sbjct: 88 NAFHTQMFNINPANGEIKTKGHLNFEVTKHYEMSVQAKDGGGLLAQSK-----VLIEII- 141
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLL-----HGY 614
+ P+ A + + GT + I V+ D+ E + +L H +
Sbjct: 142 ---DENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQDSGENGEAECHILGSSPFHKF 198
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
+ P + R I L R P Y+ +A + LS + + + DVND
Sbjct: 199 RKWKPLS-SSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIKLDISDVNDNP 257
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-----FLIANQQ-DVT 727
+ +K + + ENS N + +Y N T V+ F++ N+ ++
Sbjct: 258 PMFVKSVYKA---SISENSP---------VNTTVLYVNATDKVKHQKIAFIMDNEDFPIS 305
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+I E G ++ Q+ D E+ +++ + A + G +G + I + D NDN PV
Sbjct: 306 SYFSINIETGVLYAQRSFDYEQVKEFQIQITAS-DGGNPVRSGTALIRIAVTDSNDNLPV 364
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDE 841
F Y+ I EN I + + + ATD DEGTNA MY+ MF ++
Sbjct: 365 FTQEVYKVSISENIPINSTVL---TVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINY 421
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM-----IGDENDNKPEFNQI 896
+G +K + + E K Y++S+ A+D GG + ++++I I D NDN P F +
Sbjct: 422 TSGEIK-TKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFTKS 480
Query: 897 EENSKVRIHRE 907
S V + E
Sbjct: 481 SYVSMVPVASE 491
Score = 114 bits (275), Expect = 2e-23
Identities = 107/419 (25%), Positives = 181/419 (43%), Gaps = 42/419 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF---NSEVYIPPSKLSADALEVKRYFVINE 996
+ EN G +I + A+D D+ NG++ Y N+E + S +S ++ V
Sbjct: 3017 VTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTEKFPSFSYISINS-------VTGG 3069
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ +S L ++A DGGN +++ V D ND+FPVF + Y N+
Sbjct: 3070 EKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQEVYKVNI 3129
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGE-LDRE 1111
E + +V+A+D D G NA +TY S ++ F I+P G ++ LDRE
Sbjct: 3130 HENIPINSTVLRVNASDKDAGINAQVTYSFSTSANNVHRIFSINPNNGEITTKASTLDRE 3189
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
Y +T+ A D G D+NDN PKF + + +N
Sbjct: 3190 KTPHYNITIQATDKGSPPLSSKKTIRLDVS-DINDNPPKFEKSNYVAYVTE------NNQ 3242
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAK--VFANDTDFIG-NGNGLILYSLPQRKNQQNL- 1227
S+ I EEN + +++ V + +I N ++Y+L +Q+
Sbjct: 3243 PGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDYEQDRE 3302
Query: 1228 ----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
G PSL+S+AI+ +TV D D PVF Y++ I EN+ ++
Sbjct: 3303 FLIQIMAKDSGSPSLNSSAIVNITVTDFNDNF-----PVFTQEVYKVNIHENIPINSTVL 3357
Query: 1278 SLNLTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+N ++ E + Y + ++ R F I+P+NG + + + DRE Y + ++A
Sbjct: 3358 HVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQA 3416
Score = 111 bits (267), Expect = 1e-22
Identities = 160/660 (24%), Positives = 275/660 (41%), Gaps = 76/660 (11%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ + A+ +P + +++++ D+NDN P F Y SI EN P +VL V ATDK
Sbjct: 228 ITILATDRGSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDK 287
Query: 334 DQGENGEFTYQLDD-P-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSV 390
+ + F +D P FSI+ +G L Q D E ++++ A + NP
Sbjct: 288 VKHQKIAFIMDNEDFPISSYFSINIETGVLYA--QRSFDYEQVKEFQIQITASDGGNPVR 345
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
GT RIA N P+ T V+ + +ENI +N V +
Sbjct: 346 SGTAL--IRIAV---TDSNDNLPV-FTQEVYKVSI---SENIP---------INSTVLTV 387
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
+A D + +Y FS S + T + + ++ ++ ++ +++ +
Sbjct: 388 NATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQA- 446
Query: 511 FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
G VA S IL L + + A + +++V + +G K
Sbjct: 447 -----KDGGGFVAHSKILIKLIKLDISDVNDNAPVFTKSSYVSMVPVASEQGALITKVVA 501
Query: 571 PDFMGAPYEFWVGSNV---------GIGTSVGQIRVNDAFEQNDVSYDLLH-----GYEE 616
D + + W+ +V I + G+IR + F+ D +H +
Sbjct: 502 VD-ADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSRVFQDKDRETQTIHELILTASDG 560
Query: 617 GVPF---AVEERSGVITVVDDLSRYNRPMYDFE---AVALQE-NANLSIVTNATVHVVDV 669
G P R V D+L + + +Y +AL E + S + + + DV
Sbjct: 561 GNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISTLIALIEVHDQDSDIKLIKLDISDV 620
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND V K ++ + + + N AGA+ I+ S I + + I N T+D
Sbjct: 621 NDNAPVFTKSSY--VAYIAENNLAGAS---IYRIQASDIDAGDNAKIIYSIYNTD--TED 673
Query: 730 IAIA-------EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+++ E G ++ QKPLDRE + ++ + + A + G G + I + D ND
Sbjct: 674 YSMSSFFSINIETGVLYAQKPLDRETQSIHELILTAS-DGGNPLRTGTALIRIIVTDSND 732
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMF 837
N PVF Y+ I EN+ I + + I+ ATD DEGTNA Y++ + +F
Sbjct: 733 NLPVFTQEVYKVSISENAPINSSV---IILTATDKDEGTNAQITYSISKTSENNFYTSVF 789
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+++ G + LDRE + ++L L A D G + A + I++ D NDN P F +
Sbjct: 790 NINPVMGEITIKEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK 849
Score = 110 bits (264), Expect = 3e-22
Identities = 129/493 (26%), Positives = 212/493 (43%), Gaps = 41/493 (8%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPSN------LYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
L S V V + + D NDN+P V PS YE + +++ GT++ KV AVD D G
Sbjct: 2347 LNSSVIVTICVTDQNDNSPLVLYPSADAGGSAAYEM-VPFSSEQGTLVTKVVAVDADSGH 2405
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRY 550
N + Y + S TS F I+ T V + E + + + A D NP +
Sbjct: 2406 NAWLSYHFLQDSE---TSYFVIDQYTELVLKTSLDRENENFYEIVLTAFDG-GNPMQTGT 2461
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSY 608
+L +T+ T N + P F Y+ + N+ + ++V + +D E + ++Y
Sbjct: 2462 ALIRITV-----TDAND-NFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTY 2515
Query: 609 DLLHGYEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
++ FA+ +SG + D L Y+ AV ++ L + ++
Sbjct: 2516 SFSSASKQATNAFAINPQSGEVITKDILDFEKMKNYEI-AVQAKDGGGLISHAKVLIQIL 2574
Query: 668 DVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND V L +P+ +E++ G + I + I N F ++Q
Sbjct: 2575 DENDNPPEVSLTSITNPVS---EESAPGTVVALIANDKDEGI--NAQITYSFSATSKQAS 2629
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGAGIYQVTIYIEDENDNP 784
A G I T++ +D EK Y ++V A F+ G G + I + D NDN
Sbjct: 2630 RSFAINAISGEIKTKENIDFEKTKYYEISVQARISFDGGSPMQTGTALIRITVTDMNDNF 2689
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE---MFDVDE 841
P+F Y I EN + + + + A D D+G N+ Y+ K+ F ++
Sbjct: 2690 PIFGQEVYTVSINENIPLNSTVL---CVSANDKDQGINSQITYSFSATSKQASRSFSINS 2746
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQIEENS 900
TG +K ++LD EK Y++S+ A+ + S + I + D NDN P F Q E
Sbjct: 2747 ETGEIK-TKENLDFEKTKNYEISVQAKIQKHHILSLINIQITVTDFNDNFPVFTQ--EVY 2803
Query: 901 KVRIHRETKLNGT 913
KV IH ++ T
Sbjct: 2804 KVNIHENIPIHST 2816
Score = 109 bits (263), Expect = 4e-22
Identities = 129/497 (25%), Positives = 215/497 (43%), Gaps = 42/497 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL S ++ + + D NDN PVF+ S + ++N G I KV+A D D G+N V+Y
Sbjct: 1038 QLSSRKSILLDISDVNDNPPVFLKSRYIAYLPENNLP-GASIYKVQASDLDTGENSKVIY 1096
Query: 498 DLQRTSN--LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
+ T+ ++S F IN TG + S E A+ V+A D PS +
Sbjct: 1097 SVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDN-GYPSLSSNATL 1155
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
++ I N P + F+ + Y ++ N G ++ +I D + V Y +
Sbjct: 1156 IIRI---IDQNDNAPKM--FIKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSIS 1210
Query: 612 HGYEEGVP----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VH 665
+ E P F++ +GV+ Y + +A ++N + S+ +N T +
Sbjct: 1211 NTNTEDFPVSSYFSINIETGVLYAQRSFD-YEQDKEFHMHIAAKDNGSPSLSSNTTLIIR 1269
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
++D ND +L + + E A+I + S G+ + +
Sbjct: 1270 IMDQNDNAPKILYPSTESGDSLLFEMVPFASIEALISIQEKS------GHPVYFSLRWGN 1323
Query: 726 VTDDIAIA-EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
T+ + A I T LDREK Y +T++A ++G + + + I D NDNP
Sbjct: 1324 PTEHLKTAFIFYRIITSSALDREKASWYNITILAT-DRGSPELSSRKFIRLDILDVNDNP 1382
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE------MFD 838
P+F + Y ++ EN+ G I I A D D G NA +Y++ E F
Sbjct: 1383 PIFIKSVYNVYLPENNLPGASIYR---IHALDLDMGDNAKVIYSISNTNTEDFPVSSYFS 1439
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQI 896
++ TGV+ + S D E+ + + + A D G + A + +++ D NDN P F Q
Sbjct: 1440 INIETGVL-YAQRSFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQ- 1497
Query: 897 EENSKVRIHRETKLNGT 913
E KV I T +N T
Sbjct: 1498 -EVYKVSISENTPINST 1513
Score = 109 bits (261), Expect = 8e-22
Identities = 120/472 (25%), Positives = 193/472 (40%), Gaps = 73/472 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIPI +T++++NA D D G+N QI Y F + A V R F IN + G
Sbjct: 2807 IHENIPIHSTVLQVNASDKDEGINAQITYSFGTT-----------ATNVLRIFAINPKSG 2855
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ ++ E + +++ A DGG+L + V + + D ND+ P T V E
Sbjct: 2856 EITTKGNVDFEETKYYDISVQAQDGGSLASHAKVLIQILDENDNAPEISVTSITTPVSED 2915
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
T V+ + A D D G+N + I +PF++ +G + LDRE
Sbjct: 2916 SPTGTVVALIKAHDLDSGENGEVDCEIVGV---IPFKLLSSSGNFYKIITTSTLDREKTP 2972
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+Y LT+ D G D+NDN PKF + + +N
Sbjct: 2973 RYNLTIHTTDKG-SPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTE------NNQPGA 3025
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-----------QRKN 1223
S+ I EEN G V +F N+T+ + + + + S+ R+
Sbjct: 3026 SIYSIQAIDEDTEEN---GKVVYSIFTNNTEKFPSFSYISINSVTGGEKKSTDTSLDRET 3082
Query: 1224 QQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV 1274
Q N G P + T ++ +TV D D PVF Y++ I EN+
Sbjct: 3083 QSNHELILTASDGGNPVQTGTTLIKITVTDFNDNF-----PVFTQEVYKVNIHENIPINS 3137
Query: 1275 ELVSLNLTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVI 1332
++ +N ++ + Y + + ++ R F I+P NG + S DRE Y +
Sbjct: 3138 TVLRVNASDKDAGINAQVTYSFSTSANNVHRIFSINPNNGEITTKASTLDREKTPHYNIT 3197
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
++A K S L +K ++ + + D+NDN PKF N
Sbjct: 3198 IQA-TDKGSPPL--------------SSKKTIR--LDVSDINDNPPKFEKSN 3232
Score = 107 bits (258), Expect = 2e-21
Identities = 122/466 (26%), Positives = 198/466 (42%), Gaps = 37/466 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + DANDN PVF + +Y+ S+ N + + + V A D D G N + Y +TS
Sbjct: 833 IRIIVTDANDNLPVFTKA-VYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSE 891
Query: 505 LTITSP-FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
I SP F IN G + + E + + V+A+D + + L ++
Sbjct: 892 NDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAHSKVLLEIIN----- 946
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N P+I S G ++ ++ +D+ E + LL +
Sbjct: 947 -ENDNAPEIT-MTSVSTPIPEDSEPGTVIALIKVHDHDSGENGEAECHLLGSPPFQLVST 1004
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGA 680
+IT L R +Y+ +A + + LS + + + DVND V LK
Sbjct: 1005 SSSYYRIITT-SVLDREKVQLYNITILANDKGSPQLSSRKSILLDISDVNDNPPVFLKSR 1063
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD----VTDDIAI-AED 735
+ I ++ EN+ A I+ S + V + + N V+ +I E
Sbjct: 1064 Y---IAYLPENNLPGA--SIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIET 1118
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP-VFEHATYEG 794
G ++ Q+ D E+ + M V A+ N G S + + I I D+NDN P +F + Y
Sbjct: 1119 GVLYAQRSFDYEQHKEFAMHVQAKDN-GYPSLSSNATLIIRIIDQNDNAPKMFIKSAYTI 1177
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE------NTGVVKF 848
++ EN+ G I I A D D G NA +Y++ E F V TGV+ +
Sbjct: 1178 YLPENNLPGATIYR---IHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVL-Y 1233
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
S D E+ + + + A+D G LSS LII I D+NDN P+
Sbjct: 1234 AQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAPK 1279
Score = 106 bits (255), Expect = 4e-21
Identities = 127/471 (26%), Positives = 202/471 (42%), Gaps = 54/471 (11%)
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLG---PLFL-------IPENIPIG 947
+ KV+++ T L G ++ + LD+ + P+FL +PEN G
Sbjct: 1018 DREKVQLYNITILANDKGSP--QLSSRKSILLDISDVNDNPPVFLKSRYIAYLPENNLPG 1075
Query: 948 TTIIKLNALDLDSGLNGQIRYE-FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
+I K+ A DLD+G N ++ Y FN+ + +A V YF IN G + RS
Sbjct: 1076 ASIYKVQASDLDTGENSKVIYSVFNT---------NTEAFPVSSYFSINIETGVLYAQRS 1126
Query: 1007 LPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFP-VFKKTWYNFNVEEAQYTR 1061
E EF +++ A D G +L+ N ++ + + D ND+ P +F K+ Y + E
Sbjct: 1127 FDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIKSAYTIYLPENNLPG 1186
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDT-DLP----FEISPLTGVLSVNGELDRETEDKY 1116
+ ++ A D D G NA + Y I ++T D P F I+ TGVL D E + ++
Sbjct: 1187 ATIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDYEQDKEF 1246
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY-----AFDELLEWKHPEADELSNH 1171
+ + A+DNG D NDN+PK + D LL P A +
Sbjct: 1247 HMHIAAKDNG-SPSLSSNTTLIIRIMDQNDNAPKILYPSTESGDSLLFEMVPFASIEALI 1305
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFAN-DTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
+ + PVY + N A +F T + Y++ + G P
Sbjct: 1306 SIQEKSGHPVYFSLRWGNPTEHLKTAFIFYRIITSSALDREKASWYNITILATDR--GSP 1363
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP----VELVSLNLTEHYE 1286
LSS + + + DV D + P+FI Y + + EN N P + +L+L + +
Sbjct: 1364 ELSSRKFIRLDILDVND-----NPPIFIKSVYNVYLPEN-NLPGASIYRIHALDL-DMGD 1416
Query: 1287 NFKMRYYILNENDTD--IRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N K+ Y I N N D + F I+ G LY RS D E + + + A
Sbjct: 1417 NAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAA 1467
Score = 106 bits (255), Expect = 4e-21
Identities = 111/422 (26%), Positives = 183/422 (43%), Gaps = 48/422 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIPI +T++++NA D D+G+N Q+ Y F S A V R F IN +G
Sbjct: 3129 IHENIPINSTVLRVNASDKDAGINAQVTYSF-----------STSANNVHRIFSINPNNG 3177
Query: 1000 HVIV-ARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ A +L E + + I A D G+ L+ ++R+ V D+ND+ P F+K+ Y V
Sbjct: 3178 EITTKASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKFEKSNYVAYV 3237
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP----FEISPLTGVLSVNGELDR 1110
E + + A D D +N + Y I + + I+P+TGV+ D
Sbjct: 3238 TENNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDY 3297
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E + ++++ ++A+D+G D NDN P F E+ + E +++
Sbjct: 3298 EQDREFLIQIMAKDSGSPSLNSSAIVNITVT-DFNDNFPVFT--QEVYKVNIHENIPINS 3354
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGLILYSLP---QRKNQQ 1225
+V+ + NA I + + AN +I NG I +R +
Sbjct: 3355 ----TVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHY 3410
Query: 1226 NL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
N+ G P LSS + + V D+ D + PVF Y + EN + S
Sbjct: 3411 NITIQATDKGSPPLSSWKTIALEVLDIND-----NSPVFEKSTYIAYVPENNQPGASIYS 3465
Query: 1279 LNLTEH--YENFKMRYYILNENDTDIRRT--FVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+ + EN K+ Y I+ N ++ T I+P G +Y RS D E +E+ +
Sbjct: 3466 IQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQII 3525
Query: 1335 AE 1336
A+
Sbjct: 3526 AK 3527
Score = 96.3 bits (229), Expect = 6e-18
Identities = 201/890 (22%), Positives = 344/890 (38%), Gaps = 109/890 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL----- 499
+++ + D NDN PVF S+ Y + ++ G +I KV AVD D G N + Y +
Sbjct: 463 IKLDISDVNDNAPVFTKSS-YVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSE 521
Query: 500 -------QRTSNLTITSPFK--------INPNTGTVSVAESPILEGRHALFVEASDQPAN 544
Q T + + F+ I+ T S +P+ G + + +D N
Sbjct: 522 PSLFSISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDN 581
Query: 545 -P--SERRYSLAVVT----IEV---TRGTKGNKPDIPD-------FMGAPYEFWVGSNVG 587
P ++ Y +++ T IEV K K DI D F + Y ++ N
Sbjct: 582 LPVFTQEVYKVSISTLIALIEVHDQDSDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNL 641
Query: 588 IGTSVGQIRVND--AFEQNDVSYDLLH----GYEEGVPFAVEERSGVITVVDDLSRYNRP 641
G S+ +I+ +D A + + Y + + Y F++ +GV+ L R +
Sbjct: 642 AGASIYRIQASDIDAGDNAKIIYSIYNTDTEDYSMSSFFSINIETGVLYAQKPLDRETQS 701
Query: 642 MYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIF-HVKENSAG---A 695
+++ A + N A + ++ D ND V + + I + NS+
Sbjct: 702 IHELILTA-SDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILT 760
Query: 696 AIGQIFHTNMSSIYG---NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY 752
A + TN Y N + N V +I I E KPLDRE + +
Sbjct: 761 ATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKE-------KPLDRETQKDH 813
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
+ + A + G + I + D NDN PVF A Y+ I EN I + + N
Sbjct: 814 ELILTASDGGDPVK-TGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVN-- 870
Query: 813 KATDADEGTNALFMYTLFGEGKE-----MFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
ATD DEGTNA Y+ + MF +++ G +K + LD E Y++S+ A
Sbjct: 871 -ATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTL-QKLDFELTRNYEMSVQA 928
Query: 868 RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN-- 925
D GG + +++++ I +ENDN PE ++ + E GT +I+V +
Sbjct: 929 TDGGGFVAHSKVLLEIINENDNAPEITMTSVSTPI---PEDSEPGTV-IALIKVHDHDSG 984
Query: 926 -KFALDVDQLG-PLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
+ LG P F + II + LD + I N + S +
Sbjct: 985 ENGEAECHLLGSPPFQLVSTSSSYYRIITTSVLDREKVQLYNITILANDKGSPQLSSRKS 1044
Query: 984 DALEVKRY-----FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDV 1038
L++ + R+ + +LP S +++ S LD G N + VF +
Sbjct: 1045 ILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGE-NSKVIYSVFNTN- 1102
Query: 1039 NDHFPVFKKTWYNFNVEE-AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
+ FPV ++++ N+E Y +R D+ Q+ +Q D P S
Sbjct: 1103 TEAFPV--SSYFSINIETGVLYAQR--------SFDYEQHKEFAMHVQAKDNGYPSLSSN 1152
Query: 1098 LTGVLSVNGELDRETE--DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
T ++ + + D + K T+ +N D+ DN+ Y+
Sbjct: 1153 ATLIIRIIDQNDNAPKMFIKSAYTIYLPENN--LPGATIYRIHALDLDMGDNAKVIYSIS 1210
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL 1215
P + S N E+ ++ E++ +A N + + + LI+
Sbjct: 1211 NTNTEDFPVSSYFS-INIETGVLYAQRSFDYEQDKEFHMHIA-AKDNGSPSLSSNTTLII 1268
Query: 1216 YSLPQRKNQQNLGLPSLSSTAIL---MVTVADVPDEVEMSDK---PVFIS 1259
+ Q N + PS S L MV A + + + +K PV+ S
Sbjct: 1269 RIMDQNDNAPKILYPSTESGDSLLFEMVPFASIEALISIQEKSGHPVYFS 1318
Score = 96.3 bits (229), Expect = 6e-18
Identities = 114/459 (24%), Positives = 192/459 (41%), Gaps = 55/459 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIP+ +T++ ++A D D G+N QI Y F SA + + R F IN G
Sbjct: 2701 INENIPLNSTVLCVSANDKDQGINSQITYSF-----------SATSKQASRSFSINSETG 2749
Query: 1000 HVIVARSLPPES--EFRLNISA-LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ +L E + +++ A + ++ I++++ V D ND+FPVF + Y N+ E
Sbjct: 2750 EIKTKENLDFEKTKNYEISVQAKIQKHHILSLINIQITVTDFNDNFPVFTQEVYKVNIHE 2809
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL--PFEISPLTGVLSVNGELDRETED 1114
+ +V+A+D D G NA +TY + T++ F I+P +G ++ G +D E
Sbjct: 2810 NIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEETK 2869
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y ++V A+D G D NDN+P+ + P +++
Sbjct: 2870 YYDISVQAQDGG---SLASHAKVLIQILDENDNAPEI----SVTSITTPVSEDSPTGTV- 2921
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFA-NDTDFIGNGNGLILYSLPQRKN--QQNL---- 1227
V +I + EN + + V GN +I S R+ + NL
Sbjct: 2922 -VALIKAHDLDSGENGEVDCEIVGVIPFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHT 2980
Query: 1228 ---GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
G P+LSS + + + D+ D + P F Y + EN + S+ +
Sbjct: 2981 TDKGSPTLSSLKTIRLDILDIND-----NPPKFEKSNYVAYVTENNQPGASIYSIQAIDE 3035
Query: 1285 --YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
EN K+ Y I N+T+ +F N V +++ DT +R+ S
Sbjct: 3036 DTEENGKVVYSIFT-NNTEKFPSFSYISINS----VTGGEKKSTDT-----SLDRETQSN 3085
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
H + A D + + + + D NDN P FT
Sbjct: 3086 ---HELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFT 3121
Score = 94.3 bits (224), Expect = 2e-17
Identities = 111/431 (25%), Positives = 183/431 (42%), Gaps = 43/431 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS------LTI 130
++++ V + I D NDN P T V E +PTG + + I
Sbjct: 2883 LASHAKVLIQILDENDNAPEISVTSITTPVSEDSPTGTVVALIKAHDLDSGENGEVDCEI 2942
Query: 131 PLTVPRGL-----TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+P L +K I D+ TP ++ + D G L SS K + L
Sbjct: 2943 VGVIPFKLLSSSGNFYKIITTSTLDREKTPRYNL---TIHTTDKGSPTL-SSLKTIRL-- 2996
Query: 186 KVLDYDAGDKEFQLV-IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL- 243
+LD + +F+ +A ++ I AID+D + Y + + N K
Sbjct: 2997 DILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTEKFP 3056
Query: 244 -FSLDSVNGSLFLEKE-LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
FS S+N EK+ D + Q+N ++ + AS NP++T ++I + D ND
Sbjct: 3057 SFSYISINSVTGGEKKSTDTSLDRETQSNHELI-LTASDGGNPVQTGTTLIKITVTDFND 3115
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPR 357
N P F + Y ++I EN+P +VL+V A+DKD G N + TY ++ FSI+P
Sbjct: 3116 NFPVFTQEVYKVNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANNVHRIFSINPN 3175
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEK 416
+G +T + T LDRE + + A + + S++ + + N P EK
Sbjct: 3176 NGEITTKAST-LDREKTPHYNITIQATDKGSPPL----SSKKTIRLDVSDINDNPPKFEK 3230
Query: 417 TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF--VPSNLYEFSMKSNAK 474
+ Y V TEN ++ S +++ D +N V + +N EFS S
Sbjct: 3231 SNY-----VAYVTEN----NQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYIS 3281
Query: 475 VGTVIGKVKAV 485
+ V G + A+
Sbjct: 3282 INPVTGVIYAL 3292
Score = 91.1 bits (216), Expect = 2e-16
Identities = 57/170 (33%), Positives = 86/170 (50%), Gaps = 12/170 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G A L Y + ++ F +D L L+ LD + E N + + + A
Sbjct: 2398 AVDADSGHNAWLSYHFLQDSETSYFVIDQYT-ELVLKTSLDRENE-----NFYEIVLTAF 2451
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP++T A + I + D NDN P F + Y +SI EN+P +VL V A+DKD+G N
Sbjct: 2452 DGGNPMQTGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINS 2511
Query: 340 EFTYQLDDPK----GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ TY AF+I+P+SG V + +LD E + + V AK+
Sbjct: 2512 QLTYSFSSASKQATNAFAINPQSG--EVITKDILDFEKMKNYEIAVQAKD 2559
Score = 90.2 bits (214), Expect = 4e-16
Identities = 61/188 (32%), Positives = 93/188 (49%), Gaps = 19/188 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
IHA+D D+G A + Y + + N FS++ G L+ ++ D + Q F
Sbjct: 1407 IHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDHE-----QDKEF 1461
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ + AS P++T A + + + D NDN P F + Y +SI EN P +VL+V A+D
Sbjct: 1462 HMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASD 1521
Query: 333 KDQGENGEFTYQLDDPK------GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE- 385
D+G N + TY FSI+P SG +T + LDREA +S + + A +
Sbjct: 1522 MDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKP--LDREAQTSHELILTASDG 1579
Query: 386 TNPSVVGT 393
NP GT
Sbjct: 1580 GNPVRTGT 1587
Score = 86.2 bits (204), Expect = 6e-15
Identities = 94/426 (22%), Positives = 170/426 (39%), Gaps = 47/426 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ + + D NDN P+F Y V + E P + + +T +
Sbjct: 3106 IKITVTDFNDNFPVFTQEVYKVNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANN 3165
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHF--ALESSHK--PVLLLRKVLDYDAGD---- 194
R F + PN S + H+ ++++ K P L +K + D D
Sbjct: 3166 VHRIFSIN-PNNGEITTKASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDN 3224
Query: 195 ----KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL----ISGNDRKLFSL 246
++ V + +F I AID+D + Y + + + S+
Sbjct: 3225 PPKFEKSNYVAYVTENNQPGSSIFS--IKAIDKDTEENGKVVYSISNNTVEFSSVSYISI 3282
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+ V G ++ + D + Q F++Q+ A +P + A V I + D NDN P F
Sbjct: 3283 NPVTGVIYALQSFDYE-----QDREFLIQIMAKDSGSPSLNSSAIVNITVTDFNDNFPVF 3337
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG----AFSIDPRSGWLT 362
+ Y ++I EN+P +VL V A+DKD+G N + TY F I+P++G +
Sbjct: 3338 TQEVYKVNIHENIPINSTVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIK 3397
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKTTYVF 421
++ +R +H ++ ++ K + P S + + N+P+ EK+TY
Sbjct: 3398 IKGTLDRERSSHYNITIQATDKGSPP------LSSWKTIALEVLDINDNSPVFEKSTY-- 3449
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKSNAKVGTV 478
+ EN ++ S +++ D +N +F + SN E S S + V
Sbjct: 3450 ---IAYVPEN----NQPGASIYSIQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPV 3502
Query: 479 IGKVKA 484
G + A
Sbjct: 3503 TGVIYA 3508
Score = 83.8 bits (198), Expect = 3e-14
Identities = 168/720 (23%), Positives = 284/720 (39%), Gaps = 95/720 (13%)
Query: 532 HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS 591
H L + A+D NP +R A++ I VT ++P F Y+ + + I ++
Sbjct: 9 HELILTATDG-GNP--KRTGTALLRIIVT----DYNDNVPVFTQQVYKISISESAPINST 61
Query: 592 VGQIRVNDAFEQND--VSYDLLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFE 646
V + D + + ++Y E F + +G I L+ Y+
Sbjct: 62 VTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKGHLNFEVTKHYEM- 120
Query: 647 AVALQENANLSIVTNATVHVVDVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNM 705
+V ++ L + + ++D ND + + +PI E+SA + + +
Sbjct: 121 SVQAKDGGGLLAQSKVLIEIIDENDNAPEISIASLSTPI----PEDSAPGTLIALIEVHD 176
Query: 706 SSIYGNGTGNVRFLIAN---QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNK 762
NG L ++ + ++ + I LDRE Y +T++A ++
Sbjct: 177 QDSGENGEAECHILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILAT-DR 235
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G + + + + I D NDNPP+F + Y+ I ENS + T + + ATD +
Sbjct: 236 GSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVL---YVNATDKVKHQK 292
Query: 823 -ALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAEL 879
A M F ++ TGV+ + S D E+ +++ + A D G S A +
Sbjct: 293 IAFIMDNEDFPISSYFSINIETGVL-YAQRSFDYEQVKEFQIQITASDGGNPVRSGTALI 351
Query: 880 IIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL 939
I + D NDN P F Q E KV I +N T++ V ++ Q+ F
Sbjct: 352 RIAVTDSNDNLPVFTQ--EVYKVSISENIPINS----TVLTVNATDRDEGTNAQIMYSFS 405
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN--ER 997
+ T++ +N +G+I+ + N E K+++ I+ +
Sbjct: 406 KTSGNNLHTSMFSINY------TSGEIKTKQNFN------------FEAKKFYEISVQAK 447
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
G VA S+ + + LD ++NDN V F K+ Y V A
Sbjct: 448 DGGGFVA-----HSKILIKLIKLDISDVNDNAPV-------------FTKSSYVSMVPVA 489
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL---SVNGELDRETED 1114
++ KV A DAD G NA L+Y + F IS TG + V + DRET+
Sbjct: 490 SEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSRVFQDKDRETQT 549
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF----YAFD-----ELLEWKHPEA 1165
+ L + A D G D NDN P F Y L+E ++
Sbjct: 550 IHELILTASDGG-NPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISTLIALIEVHDQDS 608
Query: 1166 D------ELSNHNFES-VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
D ++S+ N + V Y A I EN G ++ ++ A+D D N I+YS+
Sbjct: 609 DIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDID--AGDNAKIIYSI 666
Score = 83.8 bits (198), Expect = 3e-14
Identities = 87/363 (23%), Positives = 157/363 (43%), Gaps = 26/363 (7%)
Query: 31 HVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIGA-GLNQISAYLSVTVYIED 89
+ ++L S+D ++ + F G G L+RI N S +Y
Sbjct: 2427 YTELVLKTSLDRENENFYEIVLTAFDGGNPMQTGTALIRITVTDANDNFPMFSQEIYKVS 2486
Query: 90 VNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFD 148
+N+N+P+ Y D+ + + F A + + G I KDI F+
Sbjct: 2487 INENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSGEVITKDILDFE 2546
Query: 149 RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRI 208
+ K +Y I DG + SH VL+ ++LD + E L + +
Sbjct: 2547 KMK--------NYEIAVQAKDGGGLI--SHAKVLI--QILDENDNPPEVSLTSITNPVSE 2594
Query: 209 HKEILFPEPIHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHN 266
+ A D+D G+ A + Y + + + + F++++++G + ++ +D +
Sbjct: 2595 ESAPGTVVALIANDKDEGINAQITYSFSATSKQASRSFAINAISGEIKTKENIDFEKTKY 2654
Query: 267 LQANTFVLQVQAS-QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
+ + +Q + S +P++T A + I + D+NDN P F + Y +SI EN+P +V
Sbjct: 2655 YEIS---VQARISFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENIPLNSTV 2711
Query: 326 LQVMATDKDQGENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
L V A DKDQG N + TY +FSI+ +G ++ + LD E + + V
Sbjct: 2712 LCVSANDKDQGINSQITYSFSATSKQASRSFSINSETG--EIKTKENLDFEKTKNYEISV 2769
Query: 382 YAK 384
AK
Sbjct: 2770 QAK 2772
Score = 82.6 bits (195), Expect = 8e-14
Identities = 116/465 (24%), Positives = 184/465 (39%), Gaps = 66/465 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIPI ++++ +NA D D G N QI Y F K S + + F IN+ +G
Sbjct: 856 ISENIPINSSVLHVNATDRDEGTNAQITYSF--------IKTSENDIH-SPMFSINQING 906
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E + +++ A DGG + V + + + ND+ P T + + E
Sbjct: 907 EIKTLQKLDFELTRNYEMSVQATDGGGFVAHSKVLLEIINENDNAPEITMTSVSTPIPED 966
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
V+ + D D G+N + S S + LDRE Y
Sbjct: 967 SEPGTVIALIKVHDHDSGENGEAECHLLGSPPFQLVSTSSSYYRIITTSVLDREKVQLYN 1026
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
+T++A D G DVNDN P F K L +N
Sbjct: 1027 ITILANDKGSPQLSSRKSILLDIS-DVNDNPPVFL--------KSRYIAYLPENNLPGAS 1077
Query: 1178 MIPVYKATIE--ENAPIGTTV----AKVFANDTDFIGNGNGLILYS-----LPQRKN--- 1223
+ V + ++ EN+ + +V + F + F N +LY+ Q K
Sbjct: 1078 IYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAM 1137
Query: 1224 ---QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP----VEL 1276
++ G PSLSS A L++ + D D +FI Y + + EN N P +
Sbjct: 1138 HVQAKDNGYPSLSSNATLIIRIIDQNDNA----PKMFIKSAYTIYLPEN-NLPGATIYRI 1192
Query: 1277 VSLNLTEHYENFKMRYYILNENDTD--IRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+L+L + +N K+ Y I N N D + F I+ G LY RS D
Sbjct: 1193 HALDL-DMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFD------------ 1239
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
Y ++ ++ A+D + +++RI D NDN+PK
Sbjct: 1240 -----YEQDKEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAPK 1279
Score = 77.0 bits (181), Expect = 4e-12
Identities = 50/156 (32%), Positives = 84/156 (53%), Gaps = 10/156 (6%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE + + + + A + G G + I + D NDN PVF Y+ I E++ I
Sbjct: 1 LDRETLNFHELILTAT-DGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPIN 59
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFDVDENTGVVKFIGDSLDREKK 858
+ + ++ ATD D+GTN Y+ + +MF+++ G +K G L+ E
Sbjct: 60 STV---TVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKGH-LNFEVT 115
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
Y++S+ A+D GGL ++++++I I DENDN PE +
Sbjct: 116 KHYEMSVQAKDGGGLLAQSKVLIEIIDENDNAPEIS 151
Score = 76.6 bits (180), Expect = 5e-12
Identities = 102/404 (25%), Positives = 168/404 (41%), Gaps = 51/404 (12%)
Query: 1001 VIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+I + +L E S + + I A D G+ L+ +R+ + DVND+ P+F K+ YN + E
Sbjct: 1337 IITSSALDREKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPE 1396
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDT-DLP----FEISPLTGVLSVNGELDRE 1111
+ ++ A D D G NA + Y I ++T D P F I+ TGVL D E
Sbjct: 1397 NNLPGASIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDHE 1456
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+ ++ + + A D G D NDN+P F E+ + E +++
Sbjct: 1457 QDKEFHMHIAASDGG-TPVRTGTALIRVIVTDANDNTPVF--TQEVYKVSISENTPINS- 1512
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTD----FIGNGNGLILYSLPQRKNQQNL 1227
+V+ + NA I + ++ N I +G I P + Q
Sbjct: 1513 ---TVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTS 1569
Query: 1228 ----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
G P + TA++ + V D D + PVF Y + I EN ++
Sbjct: 1570 HELILTASDGGNPVRTGTALIQIIVTDANDNL-----PVFTEVLYTVSISENTAVGSVVL 1624
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+N + N K+ Y I +E +T + F I+ G LY +S D E +E+ + A+
Sbjct: 1625 CVNAS---SNAKITYSI-SETNT-MSPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKD 1679
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ P M + + + VV + D NDN+P FT
Sbjct: 1680 NGF----PSMTSNTT------LLIHIIDRVV-VTDANDNAPVFT 1712
Score = 76.6 bits (180), Expect = 5e-12
Identities = 89/340 (26%), Positives = 146/340 (42%), Gaps = 37/340 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTI 130
G ++S+ + + I DVNDN PIF+ + Y+V + E G + L +G + +
Sbjct: 1361 GSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKV 1420
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDG---HFALESSHKPV---LLL 184
++ T + ++ T S D H A PV L
Sbjct: 1421 IYSISNTNTEDFPVSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVRTGTAL 1480
Query: 185 RKVLDYDAGD------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL--- 235
+V+ DA D +E V ++ I+ +L ++A D D G A + Y
Sbjct: 1481 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVL---RVNASDMDEGTNAQITYSFSRT 1537
Query: 236 -ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
++ +FS++ +G + +K LD +A+ + + L + AS NP++T A ++I
Sbjct: 1538 SVNSLHASMFSINPTSGEITTKKPLDREAQTSHE-----LILTASDGGNPVRTGTALIQI 1592
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--- 351
+ D NDNLP F Y +SI EN G VL V A+ N + TY + +
Sbjct: 1593 IVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNAS-----SNAKITYSISETNTMSPY 1647
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSV 390
FSI+ +G L Q D E H M++ AK+ PS+
Sbjct: 1648 FSINIETGVLYA--QQSFDYEQHKQFEMEIMAKDNGFPSM 1685
Score = 74.9 bits (176), Expect = 2e-11
Identities = 52/172 (30%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A + Y I ++ F++ G + + LD E + L +
Sbjct: 1960 VTASDKDEGTNAQITYSFIQLSETSPFTISQHTGEI-RTSQAPLDRETE---SIHELVLT 2015
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A NP++T A ++I + D NDN P F + Y +S+ EN+P ++L+V A DKD+G
Sbjct: 2016 AFDGGNPVQTGTAIIKIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGS 2075
Query: 338 NGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + TY F ID SG V+ + LD E + V AK+
Sbjct: 2076 NSQITYYFAASSKQAMNTFIIDSISG--EVKTKENLDFEKIKHYEISVQAKD 2125
Score = 74.1 bits (174), Expect = 3e-11
Identities = 78/323 (24%), Positives = 140/323 (43%), Gaps = 32/323 (9%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLT---IPLT 133
+S V I D NDN P+F Y TV+E P + +T I L+
Sbjct: 1922 MSFRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYSFIQLS 1981
Query: 134 VPRGLTIFK---DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
TI + +IR S +H +++ D G+ +++ + ++ +
Sbjct: 1982 ETSPFTISQHTGEIRTSQAPLDRETES-IHELVLTAFDGGN-PVQTGTAIIKIIVSDFND 2039
Query: 191 DAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL--FSL 246
+A +E V + ++ IL + A D+D G + + Y + + + + F +
Sbjct: 2040 NAPIFTQEVYTVSLNENIPVNSTIL---RVSANDKDEGSNSQITYYFAASSKQAMNTFII 2096
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
DS++G + ++ LD + + + + VQA + + A++ I+++D NDNLP F
Sbjct: 2097 DSISGEVKTKENLDFE-----KIKHYEISVQAKDGGGLV--SHAKILIQIIDFNDNLPVF 2149
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK----GAFSIDPRSGWLT 362
+ Y +SI EN+P ++L V A DKD+G N + Y F I+ SG +
Sbjct: 2150 SQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIM 2209
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
+ LD E + V AK+
Sbjct: 2210 TKEN--LDFEKTKLYEISVQAKD 2230
Score = 73.7 bits (173), Expect = 3e-11
Identities = 45/153 (29%), Positives = 82/153 (53%), Gaps = 12/153 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+D G+ + + Y + + + + FS++S G + ++ LD + N + +
Sbjct: 2714 VSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYE-----IS 2768
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA + + + ++I + D NDN P F + Y ++I EN+P +VLQV A+DKD+
Sbjct: 2769 VQAKIQKHHILSL-INIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDE 2827
Query: 336 GENGEFTYQL----DDPKGAFSIDPRSGWLTVR 364
G N + TY + F+I+P+SG +T +
Sbjct: 2828 GINAQITYSFGTTATNVLRIFAINPKSGEITTK 2860
Score = 70.9 bits (166), Expect = 2e-10
Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 21/185 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+HA D D G A L Y + + N FS++ G L+ ++ D + Q F
Sbjct: 1855 VHATDVDSGDNAKLIYSISNANTEDFPVSSYFSINIETGVLYAQRSFDYE-----QQKEF 1909
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+Q+ + + + + + D NDN P F D Y ++ EN+P +V+ V A+D
Sbjct: 1910 QMQITQGRSGHLMS-----FRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASD 1964
Query: 333 KDQGENGEFTY---QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNP 388
KD+G N + TY QL + F+I +G + +Q LDRE S + + A + NP
Sbjct: 1965 KDEGTNAQITYSFIQLSE-TSPFTISQHTGEIRT-SQAPLDRETESIHELVLTAFDGGNP 2022
Query: 389 SVVGT 393
GT
Sbjct: 2023 VQTGT 2027
Score = 70.1 bits (164), Expect = 4e-10
Identities = 75/327 (22%), Positives = 136/327 (41%), Gaps = 39/327 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTV-------- 134
+ + + D NDN PIF Y V+++E P +T
Sbjct: 2030 IKIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQ 2089
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDV-HYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDA 192
I I + K N + HY I V D G SH +L+ +++D++
Sbjct: 2090 AMNTFIIDSISGEVKTKENLDFEKIKHYEISVQAKDGGGLV---SHAKILI--QIIDFND 2144
Query: 193 G----DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL--FSL 246
+E V + I+ IL+ + A D+D G+ + +RY + + + L F +
Sbjct: 2145 NLPVFSQEVYKVSINENIPINSTILY---VSANDKDEGINSQIRYYFSTSSKQILNTFII 2201
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE-IELLDLNDNLPE 305
+S++G++ ++ LD + + + + VQA + A+ ++ +++ D+NDN P
Sbjct: 2202 NSISGAIMTKENLDFE-----KTKLYEISVQAKDGGGLVSHAKVLIQTLDVSDINDNPPV 2256
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-------DDPKGAFSIDPRS 358
F+ Y I EN G S+ + A D D EN + Y + P SI+P +
Sbjct: 2257 FKYPNYLAYIPENNQPGASIYSIQAIDNDSEENAKLIYSIINMNTGEPSPSSYISINPVT 2316
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G + Q D E ++++ AK+
Sbjct: 2317 G--VIYAQRSFDYEQDREFQIQIMAKD 2341
Score = 69.3 bits (162), Expect = 8e-10
Identities = 86/408 (21%), Positives = 166/408 (40%), Gaps = 45/408 (11%)
Query: 8 LNLQPVDREEDAHL---FTYRDLNRTHVSVILAQSIDSLVDSDSP---QNVVKFRLGCDF 61
+N +D +A + F+ +N H S+ + + P + L
Sbjct: 1517 VNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTA 1576
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI 121
+G + VR G L QI + D NDN+P+F + Y V++ E T G + +
Sbjct: 1577 SDGGNPVRTGTALIQI--------IVTDANDNLPVFTEVLYTVSISENTAVGS-VVLCVN 1627
Query: 122 APIGPSLTIPLTVPRGLTIFKDIRA-----FDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
A +T ++ ++ + I + + + + D+G ++ S
Sbjct: 1628 ASSNAKITYSISETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMTS 1687
Query: 177 SHKPVL-LLRKVLDYDAGD------KEFQLVIMASGKRIHKEILF------PEPIH--AI 221
+ ++ ++ +V+ DA D +E V ++ ++ +L E +H A
Sbjct: 1688 NTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDEVLHVNAT 1747
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D+D G A + Y I + FS++ G L+ ++ D + + + + L
Sbjct: 1748 DRDEGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSL 1807
Query: 282 N-NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ N +++ +++++ D+NDN P F Y + EN G S+ V ATD D G+N +
Sbjct: 1808 SSNTTLSSRKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAK 1867
Query: 341 FTYQL------DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
Y + D P + FSI+ +G L Q D E +M++
Sbjct: 1868 LIYSISNANTEDFPVSSYFSINIETGVLYA--QRSFDYEQQKEFQMQI 1913
Score = 66.1 bits (154), Expect = 7e-09
Identities = 57/212 (26%), Positives = 87/212 (41%), Gaps = 22/212 (10%)
Query: 949 TIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP 1008
T++ L A D D G+N QI Y F SA + + R F IN G + ++
Sbjct: 2600 TVVALIANDKDEGINAQITYSF-----------SATSKQASRSFAINAISGEIKTKENID 2648
Query: 1009 PESE--FRLNISA---LDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
E + +++ A DGG+ +R+ V D+ND+FP+F + Y ++ E
Sbjct: 2649 FEKTKYYEISVQARISFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENIPLN 2708
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPS--DTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ V A D D G N+ +TY + F I+ TG + LD E Y ++
Sbjct: 2709 STVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEIS 2768
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V A+ D NDN P F
Sbjct: 2769 VQAKIQ--KHHILSLINIQITVTDFNDNFPVF 2798
Score = 62.9 bits (146), Expect = 7e-08
Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 8/122 (6%)
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
N L + A+ NP +T A + I + D NDN+P F Y ISI E+ P +V V
Sbjct: 7 NFHELILTATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVT 66
Query: 330 ATDKDQGENGEFTYQLD-DPKGA-----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
ATDKD G NG TY + A F+I+P +G ++ + L+ E M V A
Sbjct: 67 ATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANG--EIKTKGHLNFEVTKHYEMSVQA 124
Query: 384 KE 385
K+
Sbjct: 125 KD 126
Score = 57.6 bits (133), Expect = 2e-06
Identities = 51/187 (27%), Positives = 84/187 (44%), Gaps = 21/187 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D G + + Y + + N FS++ G L+ ++ D + Q F
Sbjct: 1081 VQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYE-----QHKEF 1135
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPE-FEVDFYNISIVENLPNGFSVLQVMAT 331
+ VQA P ++ A + I ++D NDN P+ F Y I + EN G ++ ++ A
Sbjct: 1136 AMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIKSAYTIYLPENNLPGATIYRIHAL 1195
Query: 332 DKDQGENGEFTYQL------DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
D D G+N + Y + D P + FSI+ +G L Q D E M + AK
Sbjct: 1196 DLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYA--QRSFDYEQDKEFHMHIAAK 1253
Query: 385 ET-NPSV 390
+ +PS+
Sbjct: 1254 DNGSPSL 1260
Score = 57.6 bits (133), Expect = 2e-06
Identities = 82/371 (22%), Positives = 135/371 (36%), Gaps = 47/371 (12%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ V + D NDN P+F Y V++ E TP + + +T T
Sbjct: 1481 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVN 1540
Query: 143 DIRA-----------FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+ A KP + + ++ DG + + L +++ D
Sbjct: 1541 SLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTG----TALIQIIVTD 1596
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK-LFSLDSVN 250
A D + I + + ++ A + Y + N FS++
Sbjct: 1597 ANDNLPVFTEVLYTVSISENTAVGSVVLCVNASSN--AKITYSISETNTMSPYFSINIET 1654
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD------LNDNLP 304
G L+ ++ D + Q F +++ A P T+ + I ++D NDN P
Sbjct: 1655 GVLYAQQSFDYE-----QHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAP 1709
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDK-----------DQGENGEFTYQL--DDPKGA 351
F + Y +SI EN P VL V ATDK D+G N + TY
Sbjct: 1710 VFTEEVYTVSISENAPVNAIVLCVNATDKDEVLHVNATDRDEGTNAQITYSFIKTSVSSY 1769
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSV-VGTFADSQRIAKWRRQPLE 409
FSI+ +G L Q D E M + AK+ +PS+ T S++ K +
Sbjct: 1770 FSINIETGVLYA--QRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLDISDVN 1827
Query: 410 TNAPL-EKTTY 419
N P+ K+ Y
Sbjct: 1828 DNPPVFRKSLY 1838
Score = 51.6 bits (118), Expect = 2e-04
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+A+ + + + A+ +P +++ + +++LD+NDN P F YN+ + EN G S+ +
Sbjct: 1347 KASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPENNLPGASIYR 1406
Query: 328 VMATDKDQGENGEFTYQL------DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
+ A D D G+N + Y + D P + FSI+ +G L Q D E M
Sbjct: 1407 IHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYA--QRSFDHEQDKEFHMH 1464
Query: 381 VYAKE 385
+ A +
Sbjct: 1465 IAASD 1469
Score = 48.8 bits (111), Expect = 0.001
Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 11/127 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR----KLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D+D G + Y + ++F+++ NG + + L+ + + +
Sbjct: 65 VTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKGHLNFEVTKHYE----- 119
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ VQA L AQ++V IE++D NDN PE + + I E+ G + + D+
Sbjct: 120 MSVQAKDGGGLL--AQSKVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQ 177
Query: 334 DQGENGE 340
D GENGE
Sbjct: 178 DSGENGE 184
Score = 46.4 bits (105), Expect = 0.006
Identities = 50/190 (26%), Positives = 82/190 (43%), Gaps = 21/190 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-----LFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I AID D A L Y +I+ N + S++ V G ++ ++ D + + Q
Sbjct: 2279 IQAIDNDSEENAKLIYSIINMNTGEPSPSSYISINPVTGVIYAQRSFDYEQDREFQ---- 2334
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENLP----NGFSV 325
+Q+ A +P + V I + D NDN P D + E +P G V
Sbjct: 2335 -IQIMAKDNGSPPLNSSVIVTICVTDQNDNSPLVLYPSADAGGSAAYEMVPFSSEQGTLV 2393
Query: 326 LQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+V+A D D G N +Y L D + ++ + + L ++ T LDRE + + + A
Sbjct: 2394 TKVVAVDADSGHNAWLSYHFLQDSETSYFVIDQYTELVLK--TSLDRENENFYEIVLTAF 2451
Query: 385 E-TNPSVVGT 393
+ NP GT
Sbjct: 2452 DGGNPMQTGT 2461
Score = 46.0 bits (104), Expect = 0.008
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G P LS+ + + ++DV D + P+F+ Y+ I EN ++ +N T+ ++
Sbjct: 236 GSPQLSTMKFIKLDISDVND-----NPPMFVKSVYKASISENSPVNTTVLYVNATDKVKH 290
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
K+ +I++ D I F I+ G LY RS D E +++ + A
Sbjct: 291 QKIA-FIMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITA 337
>UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43;
Euteleostomi|Rep: Uncharacterized protein FAT3 - Homo
sapiens (Human)
Length = 4558
Score = 196 bits (479), Expect = 3e-48
Identities = 296/1214 (24%), Positives = 497/1214 (40%), Gaps = 146/1214 (12%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y + S N F ++ G + +ELD ++ + F+ V+
Sbjct: 495 VSASDKDKGENGYITYSIASLNLLP-FVINQFTGVISTTEELDFESSPEIYR--FI--VR 549
Query: 278 ASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +P + ++ V I + ++NDN P FE I + P G + V A D D+
Sbjct: 550 ASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDEL 609
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
E ++ + G F ++P SG L ++ + + +++ A + AD
Sbjct: 610 ELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGE-----NLAD 664
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLD---AN 453
I + K+ +V K + +N+E LD N
Sbjct: 665 PMSI----NISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSIN 720
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKI 513
P F S + ++K + VG I K+KA D D G NG VL+ + S+ S F I
Sbjct: 721 RQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTI---SDGNTDSCFNI 777
Query: 514 NPNTGTVSVAESPILEGRHALFVEASDQP-ANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
+ TG + V E + + NP + + L + +E P
Sbjct: 778 DMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNS------PV 831
Query: 573 FMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
F+ Y + + GIGT + Q+ R D +V+Y +L ++ FA+ +G++
Sbjct: 832 FIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQ---FAINSSTGIVY 888
Query: 631 VVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
V D L R ++ Y + A + L V V + DVND + ++S +
Sbjct: 889 VADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKV-- 946
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
+++ G I + T+ + G G G VR+ + N + +I A G I K LD E
Sbjct: 947 LEDLPVGTVIAWL-ETHDPDL-GLG-GQVRYSLVNDYNGRFEIDKAS-GAIRLSKELDYE 1002
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHATYEGFIMENSKIGTE 805
K+ Y +TV A+ +S + + V + + D N+N P F G + ENS+IGT
Sbjct: 1003 KQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTS 1062
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ + A D D G +G+ + + + +G+ +F S+D E ++ +
Sbjct: 1063 VLQ---VTARDEDSGR----------DGEIQYSIRDGSGLGRF---SIDDESGVITAADI 1106
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
+ R+T G + + + + P ++ IE IEV+ N
Sbjct: 1107 LDRETMG----SYWLTVYATDRGVVPLYSTIE-------------------VYIEVEDVN 1143
Query: 926 KFALDVDQLGPLF--LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
A + P++ ++ EN P ++I++ A D DS N ++ Y S
Sbjct: 1144 DNAPLTSE--PIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSG---------- 1191
Query: 984 DALEVKRYFVINERHGHVIV-ARSLPPE--SEFRLNISALDGGNL--NDNISVRVFVKDV 1038
+ +F IN + G + +R L E +E L ++ DGG I V V V D
Sbjct: 1192 ---NPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDE 1248
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRR--VLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
ND+ P F + Y + E +R + + A D D G NA ++Y I + D F I
Sbjct: 1249 NDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFID 1308
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
P TG++S + + D ILT+ A DNG SP FDE
Sbjct: 1309 PKTGMVSSRKQFTAGSYD--ILTIKAVDNGRPQKSSTARLHIEWIKKPPP-SPIPLTFDE 1365
Query: 1157 -LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL 1215
+ E+D ++ E V ++ V A N P+ + + G G I+
Sbjct: 1366 PFYNFTVMESDRVT----EIVGVVSVQPA----NTPLWFDIVGGNFDSAFDAEKGVGTIV 1417
Query: 1216 YSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEENVNAP 1273
+ P Q+++ S+ T V V V +V + +D P F Y++ I E+V
Sbjct: 1418 IAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPD 1477
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY--EV 1331
E++ + T+ E K+ Y + + D+ R F IDP G LY D E +D + +
Sbjct: 1478 TEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNI 1537
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA- 1390
+VR + Y R L +V+V ++D ND+SP FTN PL A
Sbjct: 1538 MVRDQEFPYRRNL-------------------ARVIVNVEDANDHSPYFTN---PLYEAS 1575
Query: 1391 IPTTAPFGYQVMQL 1404
+ +A G V+Q+
Sbjct: 1576 VFESAALGSAVLQV 1589
Score = 162 bits (393), Expect = 8e-38
Identities = 205/838 (24%), Positives = 360/838 (42%), Gaps = 68/838 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--------IGPSLTIPLTV 134
VT+ IED ND+ P F Y V+E P G + I S+ +
Sbjct: 459 VTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLL 518
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
P + F + + + + +++ IV +D G S V + ++ + +
Sbjct: 519 PFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTI--RIGNVNDNS 576
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRKLFSLDSVNGSL 253
F+ V A I + I A+ D+ ++Y++ISGN+ F L+ +G L
Sbjct: 577 PLFEKV--ACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVL 634
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
L+K L ++ F L++ A+ N + + L+ +
Sbjct: 635 QLKKSL---TNSGIKNGNFALRITATDGENLADPMSINISV----LHGKVSSKSFSCRET 687
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREA 373
+ + L +++ A K E+G + + +G + + V+ +
Sbjct: 688 RVAQKLAEKL-LIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANI 746
Query: 374 HSSLRMKVYAKET--NPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTEN 431
L++K Y ++ N V+ T +D + + +ET L+ + + N
Sbjct: 747 ---LKIKAYDADSGFNGKVLFTISDGNTDSCFNID-METGQ-LKVLMPMDREHTDLYLLN 801
Query: 432 IEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
I YD Q S+ + + + DANDN+PVF+ + Y ++ ++ +GT I +V+A D D
Sbjct: 802 ITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDS-YSVNILESSGIGTEIIQVEARDKD 860
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPS 546
LG NG V Y + LT T F IN +TG V VA+ E + ++L +EA D+ A
Sbjct: 861 LGSNGEVTYSV-----LTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDK-AESG 914
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--N 604
++ +S VVT++V + P F+ + Y V ++ +GT + + +D
Sbjct: 915 QQLFS--VVTLKVFLDDVNDCS--PAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGG 970
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNA 662
V Y L++ Y F +++ SG I + +L + Y+ A + +LS V+
Sbjct: 971 QVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFV 1028
Query: 663 TVHVVDVNDERGVLLKGAHSP---IIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRF 718
V VVDVN+ L + P ++ VKENS G ++ Q+ + S G +++
Sbjct: 1029 EVEVVDVNEN----LHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDS---GRDGEIQY 1081
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
I + + E G I LDRE Y +TV A ++GV+ +V I +E
Sbjct: 1082 SIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYAT-DRGVVPLYSTIEVYIEVE 1140
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMF 837
D NDN P+ Y +MENS + I+A D D +N Y + G + F
Sbjct: 1141 DVNDNAPLTSEPIYYPVVMENSPKDVSVIQ---IQAEDPDSSSNEKLTYRITSGNPQNFF 1197
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAEL--IIMIGDENDNKPEF 893
++ TG++ LDRE++ + L + D G ++ + ++ + DENDNKP+F
Sbjct: 1198 AINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQF 1255
Score = 126 bits (305), Expect = 4e-27
Identities = 148/595 (24%), Positives = 251/595 (42%), Gaps = 49/595 (8%)
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLDDPKGAFSIDPRSGWLTVRNQTVL 369
YN+S+ +V QV D +NG EF+ D + + P + L +
Sbjct: 1430 YNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIE---AT 1486
Query: 370 DREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKT 429
DR+ L V++ + S+ D + + L+ A + ++ + +
Sbjct: 1487 DRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEA---QDKHIL--NIMVRD 1541
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
+ Y VNVE DAND++P F + LYE S+ +A +G+ + +V A+D D
Sbjct: 1542 QEFPYRRNLARVIVNVE----DANDHSPYFT-NPLYEASVFESAALGSAVLQVTALDKDK 1596
Query: 490 GQNGMVLYDLQ--RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP 545
G+N ++Y ++ T N+ FKI P G +++ + P + G+ L ++ +DQ + P
Sbjct: 1597 GENAELIYTIEAGNTGNM-----FKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPP 1651
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
+ A+V I VT + P F+ Y+ V NV IGTSV I A Q+
Sbjct: 1652 MS---ATAIVRISVTMSDNSH----PKFIHKDYQAEVNENVDIGTSVILI---SAISQST 1701
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH 665
+ Y++ G G+ F + SGVIT L Y + +Q + +NATV+
Sbjct: 1702 LIYEVKDGDINGI-FTINPYSGVITTQKALDYERTSSYQ---LIIQATNMAGMASNATVN 1757
Query: 666 V--VDVNDERGVLLKGAHSPIIFHVKE-NSAGAAIGQI-FHTNMSSIYGNGTGNVRFLIA 721
+ VD ND V L +S + NS ++ + N + + I
Sbjct: 1758 IQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIV 1817
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDE 780
+ G I T LD E + V + + ++ +V I + D
Sbjct: 1818 ESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDV 1877
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDNPPVF A +E ++ + +G E+ + ATD D Y+L + F +D
Sbjct: 1878 NDNPPVFTQAVFETILLLPTYVGVEVLK---VSATDPDSEVPPELTYSLMEGSLDHFLID 1934
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
N+GV+ ++L ++ Y L + D G S + + IM+ + D+ F Q
Sbjct: 1935 SNSGVLTIKNNNLSKDH---YMLIVKVSD-GKFYSTSMVTIMVKEAMDSGLHFTQ 1985
Score = 121 bits (291), Expect = 2e-25
Identities = 115/472 (24%), Positives = 216/472 (45%), Gaps = 37/472 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F V V ++D NDN P F+ Y S++++ G ++ +V+A+DPD G N + Y L
Sbjct: 2583 TFCTVRVIVVDENDNAPQFMTVE-YRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLY 2641
Query: 501 RTSNLTITSPFKINPNTG-TVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTIE 558
+++++ +I+P+ G V+ L+ + FV+A D ++SL V I
Sbjct: 2642 SEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVD---GGIPVKHSLIPVYIH 2698
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG----Y 614
V + +P F + Y F + + IG++V +R+ +V + ++G
Sbjct: 2699 VL----PPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRI---LPSQNVWFSTVNGERPEN 2751
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL--QENANLSIVTNATVHVVDVNDE 672
+G F +E+ +G I + L R P + F+ A + ++ + + V+D+ND
Sbjct: 2752 NKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDN 2811
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI---ANQQDVTDD 729
+ V ++ II ++ G + Q+ +M +G G V + + + + V +
Sbjct: 2812 KPVFETSSYDTII--MEGMPVGTKLTQVRAIDMD--WG-ANGQVTYSLHSDSQPEKVMEA 2866
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I + G I T K LD E + +V+A S + V++ + D NDN PVF
Sbjct: 2867 FNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFA 2926
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFG---EGKEMFDVDENTG 844
Y G + E+ G + ++ D D N Y + G G+ + ++
Sbjct: 2927 QEVYRGNVKESDPPGEVVA---VLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEW 2983
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
V ++ LDRE++ +Y L++ A D G ++A + + + D NDN P +Q+
Sbjct: 2984 KV-YVKRPLDREEQDIYFLNITATD-GLFVTQAMVEVSVSDVNDNSPVCDQV 3033
Score = 120 bits (290), Expect = 2e-25
Identities = 144/568 (25%), Positives = 240/568 (42%), Gaps = 52/568 (9%)
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
E DV Y L G E+ V F + RSG+I L+ + +Y E N +
Sbjct: 404 EPIDVEYKLSPG-EDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVT----NKEGDLKAQ 458
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLI 720
T+ + D ND + + +V E+ +G T +S G G + + I
Sbjct: 459 VTISIEDANDHTPEFQQPLYDA---YVNES---VPVGTSVLTVSASDKDKGENGYITYSI 512
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKR-DVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
A+ ++ + G I T + LD E ++YR V A VTI I +
Sbjct: 513 ASL-NLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGN 571
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--F 837
NDN P+FE +G I + +G I + A D DE L Y + G E+ F
Sbjct: 572 VNDNSPLFEKVACQGVISYDFPVGGHI---TAVSAIDIDE--LELVKYKIIS-GNELGFF 625
Query: 838 DVDENTGVVKFIGDSLDRE--KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN- 894
++ ++GV++ + SL K + L + A D L+ + I + + F+
Sbjct: 626 YLNPDSGVLQ-LKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKSFSC 684
Query: 895 -------QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-IPENIPI 946
++ E ++ KLN GF ++ N+ D+ P + + E++P+
Sbjct: 685 RETRVAQKLAEKLLIKAKANGKLNLEDGF--LDFYSINRQGPYFDKSFPSDVAVKEDLPV 742
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G I+K+ A D DSG NG++ + + + + ++K ++ H +
Sbjct: 743 GANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDL----- 797
Query: 1007 LPPESEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
+ LNI+ D GN + + + V+D ND+ PVF + Y+ N+ E+ +
Sbjct: 798 ------YLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEI 851
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+V+A D D G N +TY + +DT F I+ TG++ V +LDRE++ Y L + ARD
Sbjct: 852 IQVEARDKDLGSNGEVTYSVL-TDTQ-QFAINSSTGIVYVADQLDRESKANYSLKIEARD 909
Query: 1125 NG-XXXXXXXXXXXXXXXXDVNDNSPKF 1151
DVND SP F
Sbjct: 910 KAESGQQLFSVVTLKVFLDDVNDCSPAF 937
Score = 117 bits (282), Expect = 2e-24
Identities = 137/508 (26%), Positives = 209/508 (41%), Gaps = 66/508 (12%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF-- 970
T + V N + DQ+ L+PE+IP I+K++A D D G NG IRY
Sbjct: 3012 TQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYG 3071
Query: 971 --NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDN 1028
NSE ++ P ++ E+K +++ +P + L A DGG
Sbjct: 3072 SGNSEFFLDP-----ESGELKTLALLDRER--------IP---VYSLMAKATDGGGRFCQ 3115
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
++ + ++DVND+ PVF YN V E T+ +L +V A D D G N + Y + S
Sbjct: 3116 SNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSA 3175
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
+ F I +G++ + LDRE + Y ++V A D D+NDN
Sbjct: 3176 GGV-FSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNP 3234
Query: 1149 PKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI------GTTVAKVFAN 1202
P F D L+ PE V+ + I NA I G K N
Sbjct: 3235 PVFERRDYLV--TVPEDTSPGT----QVLAVFATSKDIGTNAEITYLIRSGNEQGKFKIN 3288
Query: 1203 DTDFIGNGNGLILYSLPQR----KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFI 1258
+ + ++ Y L +R ++ G P+LS+ A + + + DV D + P F
Sbjct: 3289 PKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVND-----NPPKFS 3343
Query: 1259 SRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
Y I E+ V V L+ + N ++ + I+N D D F +DP G +
Sbjct: 3344 QDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVN-GDRD--NEFTVDPVLGLVK 3400
Query: 1317 LVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDN 1376
+ + DRE Y ++V+A +P M V + I DVNDN
Sbjct: 3401 VKKKLDRERVSGYSLLVQA----VDSGIPAM-------------SSTATVNIDISDVNDN 3443
Query: 1377 SPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
SP FT N V I P G ++QL
Sbjct: 3444 SPVFTPANYTAV--IQENKPVGTSILQL 3469
Score = 114 bits (274), Expect = 2e-23
Identities = 122/470 (25%), Positives = 202/470 (42%), Gaps = 31/470 (6%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
NI D ++ VEV++ D NDN+PV Y + + +I KV A D D+G
Sbjct: 3002 NITATDGLFVTQAMVEVSVSDVNDNSPV-CDQVAYTALLPEDIPSNKIILKVSAKDADIG 3060
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
NG + Y L + N S F ++P +G + L R + V + A R+
Sbjct: 3061 SNGYIRYSLYGSGN----SEFFLDPESGELKTLA---LLDRERIPVYSLMAKATDGGGRF 3113
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSY 608
+ + + + N P F Y V N + +++ D V Y
Sbjct: 3114 CQSNIHL-ILEDVNDNPPV---FSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVY 3169
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHV 666
L G F+++ SG+I + L R + Y+ A ++ +LS +T T+ V
Sbjct: 3170 SLADS--AGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITV 3227
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
+D+ND V + + ++ ++ S G + +F T+ I N + +LI + +
Sbjct: 3228 LDINDNPPVFERRDY--LVTVPEDTSPGTQVLAVFATS-KDIGTNA--EITYLIRSGNEQ 3282
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+ G I + LD E + + V A+ + G + + + V I + D NDNPP
Sbjct: 3283 GKFKINPKTGGISVSEVLDYELCKRFYLVVEAK-DGGTPALSAVATVNINLTDVNDNPPK 3341
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
F Y I E++ +G + + + A D D N +++ G+ F VD G+
Sbjct: 3342 FSQDVYSAVISEDALVGDSVIL---LIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGL 3398
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
VK + LDRE+ Y L + A D+G +SS A + I I D NDN P F
Sbjct: 3399 VK-VKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVF 3447
Score = 113 bits (271), Expect = 5e-23
Identities = 119/458 (25%), Positives = 200/458 (43%), Gaps = 34/458 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+ + L D NDN PVF S+ Y + N ++ +V+AVDPD+G N V+Y L ++
Sbjct: 3117 NIHLILEDVNDNPPVF-SSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSA 3175
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F I+ ++G + + E P+ + + + V A+DQ +P + SL VTI V
Sbjct: 3176 G----GVFSIDSSSGII-ILEQPLDREQQSSYNISVRATDQ--SPGQSLSSLTTVTITVL 3228
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGV 618
+ P P F Y V + GT V + D +++Y + G E+G
Sbjct: 3229 --DINDNP--PVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQG- 3283
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVL 676
F + ++G I+V + L Y + V ++ LS V +++ DVND
Sbjct: 3284 KFKINPKTGGISVSEVLD-YELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKF 3342
Query: 677 LKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ +S +I S A +G + + G + F I N +
Sbjct: 3343 SQDVYSAVI------SEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVL 3396
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + +K LDRE+ Y + V A + G+ + + V I I D NDN PVF A Y
Sbjct: 3397 GLVKVKKKLDRERVSGYSLLVQA-VDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAV 3455
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I EN +GT I + ++ D+ L G +E F +D + G+++
Sbjct: 3456 IQENKPVGTSI-LQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPH-GILR-SAVVFQH 3512
Query: 856 EKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKP 891
+ + Y L + A+D+G S + + + +E+ +KP
Sbjct: 3513 TESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKP 3550
Score = 110 bits (265), Expect = 2e-22
Identities = 117/479 (24%), Positives = 206/479 (43%), Gaps = 31/479 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN-GMVLYDL 499
S + V + +L P F S Y F++ + +G+ + ++ + QN +
Sbjct: 2691 SLIPVYIHVLPPETFLPSFTQSQ-YSFTIAEDTAIGSTVDTLRILP---SQNVWFSTVNG 2746
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLAVVTIE 558
+R N F I TGT+ + + E A F A+ P + + V T++
Sbjct: 2747 ERPEN-NKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVD-----IVFTVD 2800
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYE- 615
V + P F + Y+ + + +GT + Q+R D V+Y L +
Sbjct: 2801 VDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQP 2860
Query: 616 EGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLSIVTNATVHVVDVND 671
E V F ++ +G I+ + DL P + F VA L E +LS +V V D+ND
Sbjct: 2861 EKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDIND 2920
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIANQQDVTDDI 730
V + + +VKE+ + + T + + N + N +
Sbjct: 2921 NAPVFAQEVYRG---NVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALG 2977
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ + ++ ++PLDRE++D+Y + + A G+ + +V++ D NDN PV +
Sbjct: 2978 LVQSEWKVYVKRPLDREEQDIYFLNITA--TDGLFVTQAMVEVSV--SDVNDNSPVCDQV 3033
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y + E+ I + A DAD G+N Y+L+G G F +D +G +K +
Sbjct: 3034 AYTALLPEDIPSNKIILK---VSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLA 3090
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LDRE+ +Y L A D GG ++ + +++ D NDN P F+ N+ V + TK
Sbjct: 3091 -LLDRERIPVYSLMAKATDGGGRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATK 3148
Score = 100 bits (240), Expect = 3e-19
Identities = 121/475 (25%), Positives = 202/475 (42%), Gaps = 36/475 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D ++ V V V + D NDN+PVFV Y +++ +A+ GT+I +V A+D D G NG V
Sbjct: 2062 DHLRVARVVVRVNIEDINDNSPVFVGLPYYA-AVQVDAEPGTLIYQVTAIDKDKGPNGEV 2120
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE---SPILEGRHALFVEASDQPANPSERRYSL 552
Y LQ F+INPN+G V + E S + + + + A D L
Sbjct: 2121 TYVLQDDYG-----HFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVEL 2175
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
+ + NK +P F Y V ++ + T + I E + Y ++
Sbjct: 2176 PITIV--------NKA-MPVFDKPFYTASVNEDIRMNTPILSINATSP-EGQGIIYIIID 2225
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G + F ++ +GV+ VV L Y A + V DVND
Sbjct: 2226 G-DPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDN 2284
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIA 731
+ + ++ + + G + Q+ + S V + ++ + + TD
Sbjct: 2285 PPIFDQPTYNTTLSEA--SLIGTPVLQVVSIDADS---ENNKMVHYQIVQDTYNSTDYFH 2339
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I + G I T + LD E V T+ + + G S + V IYI D NDNPPVF
Sbjct: 2340 IDSSSGLILTARMLDHEL--VQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQ 2397
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKF 848
YE ++ E + G + ++A+DAD Y+ L G + F +D +GV+
Sbjct: 2398 LIYESYVSELAPRGHFV---TCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVIT- 2453
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+ + + + +Y L++ D G +S A++ I + N P F+Q ++VR
Sbjct: 2454 LSNHRKQRMEPLYSLNVSVSD-GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVR 2507
Score = 91.5 bits (217), Expect = 2e-16
Identities = 90/328 (27%), Positives = 145/328 (44%), Gaps = 30/328 (9%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGL--- 138
++ + +EDVNDN P+F Y+ V E T T KA + + + P + I V L
Sbjct: 3117 NIHLILEDVNDNPPVFSSDHYNTCVYENTAT--KALLTRVQAVDPDIGINRKVVYSLADS 3174
Query: 139 -----TIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+I ++P Y+I V D SS V + VLD +
Sbjct: 3175 AGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTIT--VLDIND 3232
Query: 193 GDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
F+ LV + ++L + A +D+G A + Y + SGN++ F ++
Sbjct: 3233 NPPVFERRDYLVTVPEDTSPGTQVL---AVFATSKDIGTNAEITYLIRSGNEQGKFKINP 3289
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
G + + + LD + F L V+A P +A A V I L D+NDN P+F
Sbjct: 3290 KTGGISVSEVLDYEL-----CKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQ 3344
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
D Y+ I E+ G SV+ ++A D D NG+ + + D F++DP G + V+ +
Sbjct: 3345 DVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKK 3404
Query: 367 TVLDREAHSSLRMKVYAKETN-PSVVGT 393
LDRE S + V A ++ P++ T
Sbjct: 3405 --LDRERVSGYSLLVQAVDSGIPAMSST 3430
Score = 90.2 bits (214), Expect = 4e-16
Identities = 103/387 (26%), Positives = 170/387 (43%), Gaps = 47/387 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN + ++ A+D D G+N ++ Y SA + F I+ G +
Sbjct: 3143 ENTATKALLTRVQAVDPDIGINRKVVYSLAD---------SAGGV-----FSIDSSSGII 3188
Query: 1002 IVARSLPPESEFRLNIS--ALD---GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
I+ + L E + NIS A D G +L+ +V + V D+ND+ PVF++ Y V E
Sbjct: 3189 ILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPE 3248
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ V AT D G NA +TY I+ + F+I+P TG +SV+ LD E ++
Sbjct: 3249 DTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRF 3308
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L V A+D G DVNDN PKF ++ E D L +SV
Sbjct: 3309 YLVVEAKDGG-TPALSAVATVNINLTDVNDNPPKF--SQDVYSAVISE-DALVG---DSV 3361
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL------ 1227
+++ + N I ++ ++ + GL+ +R + +L
Sbjct: 3362 ILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVD 3421
Query: 1228 -GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH-- 1284
G+P++SSTA + + ++DV D + PVF Y I+EN ++ L +T+
Sbjct: 3422 SGIPAMSSTATVNIDISDVND-----NSPVFTPANYTAVIQENKPVGTSILQLVVTDRDS 3476
Query: 1285 -YENFKMRYYILNENDTDIRRTFVIDP 1310
+ + IL+ N+ + FV+DP
Sbjct: 3477 FHNGPPFSFSILSGNEEE---EFVLDP 3500
Score = 89.4 bits (212), Expect = 7e-16
Identities = 129/526 (24%), Positives = 217/526 (41%), Gaps = 62/526 (11%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I E +P+GT + ++ A+D+D G NGQ+ Y +S+ P K V F I+
Sbjct: 2823 IIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSD--SQPEK-------VMEAFNIDSNT 2873
Query: 999 GHVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + + L E++ F ++ A D G +L+ V V V D+ND+ PVF + Y N
Sbjct: 2874 GWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGN 2933
Query: 1054 VEEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDR 1110
V+E+ V+ + D D N ++Y I + F + + + V LDR
Sbjct: 2934 VKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDR 2993
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP--KFYAFDELLEWKHPEADEL 1168
E +D Y L + A D DVNDNSP A+ LL PE D
Sbjct: 2994 EEQDIYFLNITATDG----LFVTQAMVEVSVSDVNDNSPVCDQVAYTALL----PE-DIP 3044
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG-LILYSLPQRKNQQNL 1227
SN + ++ + A I N I ++ N F+ +G L +L R+
Sbjct: 3045 SN---KIILKVSAKDADIGSNGYIRYSLYG-SGNSEFFLDPESGELKTLALLDRERIPVY 3100
Query: 1228 GLPSLSSTA---ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
L + ++ + + ++V + PVF S +Y + EN L + +
Sbjct: 3101 SLMAKATDGGGRFCQSNIHLILEDVN-DNPPVFSSDHYNTCVYENTATKALLTRVQAVDP 3159
Query: 1285 YENFKMR-YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
+ Y L ++ + F ID +G + L + DRE + +Y + VRA Q +
Sbjct: 3160 DIGINRKVVYSLADSAGGV---FSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQS 3216
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
L + V + + D+NDN P F + LVT T+P G QV+
Sbjct: 3217 LSSL----------------TTVTITVLDINDNPPVFERRDY-LVTVPEDTSP-GTQVLA 3258
Query: 1404 LKGA---IGHHPTASRTVRADTDELVFFERLSLNGLTSPQATDSDI 1446
+ IG + + +R+ ++ F G++ + D ++
Sbjct: 3259 VFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYEL 3304
Score = 89.0 bits (211), Expect = 9e-16
Identities = 108/431 (25%), Positives = 172/431 (39%), Gaps = 46/431 (10%)
Query: 987 EVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPV 1044
++ F IN G + ++L E S ++L I A + + N +V + + D ND+ PV
Sbjct: 1710 DINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPV 1769
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVD-------ATDADFGQNANLTYFIQPSDTDLPFEISP 1097
F + Y+ ++ EA ++ +D ATDAD +NA L Y I S F +
Sbjct: 1770 FLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKFFTVDS 1829
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX-XXXXXXXXDVNDNSPKF-YAFD 1155
TG + LD ET + V RD+G DVNDN P F A
Sbjct: 1830 STGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVF 1889
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN-DTDFIGNGNGLI 1214
E + L + V ++ V + P T + + + D I + +G++
Sbjct: 1890 ETI---------LLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSLDHFLIDSNSGVL 1940
Query: 1215 LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV 1274
+ + +S ++ + + M F +Y I EN
Sbjct: 1941 TIKNNNLSKDHYMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNIT 2000
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIV 1333
++ +N + N ++Y ILN + F I +G + P DRE ++ YE++V
Sbjct: 2001 KVAIVNAVGNRLNEPLKYSILNPGNK-----FKIKSTSGVIQTTGVPFDREEQELYELVV 2055
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
A SREL H+ VA V V V I+D+NDNSP F P A+
Sbjct: 2056 EA-----SRELDHL--RVAR----------VVVRVNIEDINDNSPVFV--GLPYYAAVQV 2096
Query: 1394 TAPFGYQVMQL 1404
A G + Q+
Sbjct: 2097 DAEPGTLIYQV 2107
Score = 87.8 bits (208), Expect = 2e-15
Identities = 114/483 (23%), Positives = 194/483 (40%), Gaps = 46/483 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ D + S V + + +A D+ F S Y S+ N T + V AV L
Sbjct: 1956 VKVSDGKFYSTSMVTIMVKEAMDSGLHFTQS-FYSTSISENNTNITKVAIVNAVGNRL-- 2012
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS 551
N + Y + N FKI +G + P L+ + R +
Sbjct: 2013 NEPLKYSILNPGN-----KFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVA 2067
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYD 609
VV + + + + P F+G PY V + GT + Q+ D +V+Y
Sbjct: 2068 RVVVRVNI----EDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYV 2123
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE---AVALQENANLSIVTNATVHV 666
L Y F + SG + + + +N + + E + ++ S+ T+ + +
Sbjct: 2124 LQDDYGH---FEINPNSGNVILKE---AFNSDLSNIEYGVTILAKDGGKPSLSTSVELPI 2177
Query: 667 VDVNDERGVLLKGAHSPIIFH-VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
VN V K ++ + ++ N+ I N +S G G + ++I +
Sbjct: 2178 TIVNKAMPVFDKPFYTASVNEDIRMNTP------ILSINATSPEGQG---IIYIIIDGDP 2228
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI-YQVTIYIEDENDNP 784
+ G + PLD E Y++T+ A ++GA V + + D NDNP
Sbjct: 2229 FKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRAS---DALTGARAEVTVDLLVNDVNDNP 2285
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GKEMFDVDE 841
P+F+ TY + E S IGT + + + DAD N + Y + + + F +D
Sbjct: 2286 PIFDQPTYNTTLSEASLIGTPVLQ---VVSIDADSENNKMVHYQIVQDTYNSTDYFHIDS 2342
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEEN 899
++G++ LD E L + + D+G LSSE + I I D NDN P FNQ+
Sbjct: 2343 SSGLI-LTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYE 2401
Query: 900 SKV 902
S V
Sbjct: 2402 SYV 2404
Score = 87.8 bits (208), Expect = 2e-15
Identities = 108/405 (26%), Positives = 169/405 (41%), Gaps = 53/405 (13%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT I ++ A+D D G NG++ Y + +F IN G+VI+ +
Sbjct: 2101 GTLIYQVTAIDKDKGPNGEVTYVLQDDY---------------GHFEINPNSGNVILKEA 2145
Query: 1007 LPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV 1063
+ E+ + I A DGG + + SV + + VN PVF K +Y +V E
Sbjct: 2146 FNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTP 2205
Query: 1064 LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
+ ++AT + GQ + Y I D F I TGVL V LD E Y LT+ A
Sbjct: 2206 ILSINATSPE-GQ--GIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRAS 2262
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE-LLEWKHPEADELSNHNFESVMMIPVY 1182
D DVNDN P FD+ EA + V+ +
Sbjct: 2263 D--ALTGARAEVTVDLLVNDVNDNPP---IFDQPTYNTTLSEASLIGT----PVLQVVSI 2313
Query: 1183 KATIEENAPIGTTVAKVFANDTDF--IGNGNGLIL------YSLPQ----RKNQQNLGLP 1230
A E N + + + N TD+ I + +GLIL + L Q + + G P
Sbjct: 2314 DADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFP 2373
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP--VELVSLNLTEHYENF 1288
SLSS ++ + ++DV D + PVF YE + E V V + + +
Sbjct: 2374 SLSSEVLVHIYISDVND-----NPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFD 2428
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
++ Y IL+ ND R +F++D ++G + L + ++ Y + V
Sbjct: 2429 RLEYSILSGND---RTSFLMDSKSGVITLSNHRKQRMEPLYSLNV 2470
Score = 87.8 bits (208), Expect = 2e-15
Identities = 79/282 (28%), Positives = 133/282 (47%), Gaps = 20/282 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLL 677
F ++ SG + + L R P+Y A A + +H++ DVND V
Sbjct: 3077 FFLDPESGELKTLALLDRERIPVYSLMAKATDGGGRFC---QSNIHLILEDVNDNPPVFS 3133
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDG 736
++ ++ EN+A A+ T + ++ + N + + + +I + G
Sbjct: 3134 SDHYNTCVY---ENTATKAL----LTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSG 3186
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I ++PLDRE++ Y ++V A S + + VTI + D NDNPPVFE Y +
Sbjct: 3187 IIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTV 3246
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDR 855
E++ GT++ + AT D GTNA Y + G + F ++ TG + + + LD
Sbjct: 3247 PEDTSPGTQVL---AVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGIS-VSEVLDY 3302
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
E + L + A+D G LS+ A + I + D NDN P+F+Q
Sbjct: 3303 ELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQ 3344
Score = 83.0 bits (196), Expect = 6e-14
Identities = 91/362 (25%), Positives = 155/362 (42%), Gaps = 30/362 (8%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISA---LDGGNLNDNISVRVFVKDVNDHFPVFK 1046
FVI + G + + + L E+ F ++A LD ++ + V + V D+ND+ PVF+
Sbjct: 2757 FVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFE 2816
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI----QPSDTDLPFEISPLTGVL 1102
+ Y+ + E L +V A D D+G N +TY + QP F I TG +
Sbjct: 2817 TSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWI 2876
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH 1162
S +LD ET+ + +VVA D G D+NDN+P F E+
Sbjct: 2877 STLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVF--AQEVYRGNV 2934
Query: 1163 PEADELSNHNFESVMMIPVY-KATIEENAPIGTTVAKVFANDTDFIG--NGNGLILYSLP 1219
E+D E V ++ + + T + N + + +G + P
Sbjct: 2935 KESDPPG----EVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRP 2990
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD----KPVFISRYYELEIEENV--NAP 1273
+ +Q++ ++++T L VT A V EV +SD PV Y + E++ N
Sbjct: 2991 LDREEQDIYFLNITATDGLFVTQAMV--EVSVSDVNDNSPVCDQVAYTALLPEDIPSNKI 3048
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
+ VS + N +RY + +++ F +DP +G L + DRE Y ++
Sbjct: 3049 ILKVSAKDADIGSNGYIRYSLYGSGNSE----FFLDPESGELKTLALLDRERIPVYSLMA 3104
Query: 1334 RA 1335
+A
Sbjct: 3105 KA 3106
Score = 82.2 bits (194), Expect = 1e-13
Identities = 109/470 (23%), Positives = 191/470 (40%), Gaps = 40/470 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+VE+ + N PVF Y S+ + ++ T I + A P+ GQ ++Y +
Sbjct: 2172 SVELPITIVNKAMPVF-DKPFYTASVNEDIRMNTPILSINATSPE-GQG--IIYIIIDGD 2227
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F I+ +TG + V SP+ + + L + ASD + A VT+++
Sbjct: 2228 PF---KQFNIDFDTGVLKVV-SPLDYEVTSAYKLTIRASDALTG------ARAEVTVDLL 2277
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG-YEEG 617
+ P P F Y + IGT V Q+ DA +N+ V Y ++ Y
Sbjct: 2278 VNDVNDNP--PIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNST 2335
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVL 676
F ++ SG+I L + ++ +LS +++ DVND V
Sbjct: 2336 DYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVF 2395
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + + + Q + S + + I + D T + ++ G
Sbjct: 2396 NQLIYESYVSELAPRGHFVTCVQASDADSSDF-----DRLEYSILSGNDRTSFLMDSKSG 2450
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I + +Y + V + G+ + QV I + N P F +TY +
Sbjct: 2451 VITLSNHRKQRMEPLYSLNV--SVSDGLFTSTA--QVHIRVLGANLYSPAFSQSTYVAEV 2506
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGDSLDR 855
EN GT++ ++ATD D GT Y + + K+ F +D N V+ + LDR
Sbjct: 2507 RENVAAGTKVIH---VRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITT--ERLDR 2561
Query: 856 EKKIMYKLSLVAR--DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
E + +S+ R D GG ++ + +++ DENDN P+F +E + VR
Sbjct: 2562 ENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVR 2611
Score = 81.8 bits (193), Expect = 1e-13
Identities = 90/349 (25%), Positives = 149/349 (42%), Gaps = 30/349 (8%)
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNV 1054
G +++A+ L E S + +++ DG N+ +VF+K D ND+ P F + Y+ +
Sbjct: 1414 GTIVIAKPLDAEQRSIYNMSVEVTDGTNV---AVTQVFIKVLDNNDNGPEFSQPNYDVTI 1470
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL---PFEISPLTGVLSVNGELDRE 1111
E + +++ATD D + L+Y + S + F I P TGVL LD E
Sbjct: 1471 SEDVLPDTEILQIEATDRD--EKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHE 1528
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+DK+IL ++ RD D ND+SP Y + L E E+ L +
Sbjct: 1529 AQDKHILNIMVRDQ-EFPYRRNLARVIVNVEDANDHSP--YFTNPLYEASVFESAALGS- 1584
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQ--RKNQQNLG 1228
+V+ + ENA + T+ + I G+I + P Q L
Sbjct: 1585 ---AVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLS 1641
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDK--PVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
+ + M A V V MSD P FI + Y+ E+ ENV+ ++ ++
Sbjct: 1642 IKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISA----- 1696
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
I D DI F I+P +G + ++ D E +Y++I++A
Sbjct: 1697 -ISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQA 1744
Score = 81.8 bits (193), Expect = 1e-13
Identities = 97/395 (24%), Positives = 163/395 (41%), Gaps = 35/395 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPSLTIP 131
+S+ V+V + D+NDN P+F Y V E P GE + + + ++
Sbjct: 2905 LSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYH 2964
Query: 132 LTV--PRGL----TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+T PRG + + + + + + D+++ ++ D G F ++ + + +
Sbjct: 2965 ITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATD-GLFVTQAMVE--VSVS 3021
Query: 186 KVLDYD-AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
V D D+ ++ +K IL + A D D+G +RY L + + F
Sbjct: 3022 DVNDNSPVCDQVAYTALLPEDIPSNKIIL---KVSAKDADIGSNGYIRYSLYGSGNSEFF 3078
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
LD +G L K L L + V + A + + Q+ + + L D+NDN P
Sbjct: 3079 -LDPESGEL---KTLALLDRERIP----VYSLMAKATDGGGRFCQSNIHLILEDVNDNPP 3130
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTV 363
F D YN + EN + +V A D D G N + Y L D G FSID SG + +
Sbjct: 3131 VFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIIL 3190
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKTTYV-- 420
+ LDRE SS + V A + +P G S + N P+ E+ Y+
Sbjct: 3191 --EQPLDREQQSSYNISVRATDQSP---GQSLSSLTTVTITVLDINDNPPVFERRDYLVT 3245
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDN 455
P+ T+ + + N E+T L + N
Sbjct: 3246 VPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGN 3280
Score = 80.2 bits (189), Expect = 4e-13
Identities = 110/432 (25%), Positives = 176/432 (40%), Gaps = 35/432 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+ L S V +T+LD NDN PVF + Y ++ + GT + V A D+G N +
Sbjct: 3215 QSLSSLTTVTITVLDINDNPPVFERRD-YLVTVPEDTSPGTQVLAVFATSKDIGTNAEIT 3273
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
Y L R+ N FKINP TG +SV+E E R L VEA D P+ AV
Sbjct: 3274 Y-LIRSGN--EQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKD-GGTPA----LSAV 3325
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLH 612
T+ + + P P F Y + + +G SV + D Q + + +++
Sbjct: 3326 ATVNINLTDVNDNP--PKFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVN 3383
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVND 671
G + F V+ G++ V L R Y A+ +S + + DVND
Sbjct: 3384 GDRDN-EFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVND 3442
Query: 672 ERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTD 728
V ++ +I +EN G +I Q+ T+ S + + L N+++ V D
Sbjct: 3443 NSPVFTPANYTAVI---QENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLD 3499
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I +F Q E Y + V A+ + G + + + +E+ + P
Sbjct: 3500 PHGILRSAVVF-QHTESLE----YVLCVQAK-DSGKPQQVSHTYIRVRVIEESTHKPTAI 3553
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
ME+ G I I ATD D + + L E K +F V+ + G +
Sbjct: 3554 PLEIFIVTMEDDFPGGVI---GKIHATDQD--MYDVLTFALKSEQKSLFKVNSHDGKIIA 3608
Query: 849 IGDSLDREKKIM 860
+G LD K ++
Sbjct: 3609 LG-GLDSGKYVL 3619
Score = 78.2 bits (184), Expect = 2e-12
Identities = 79/296 (26%), Positives = 131/296 (44%), Gaps = 22/296 (7%)
Query: 72 AGLNQISAYLSVTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+G Q++A V V IE DVNDN P+F + + L PT + ++ P
Sbjct: 1857 SGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETIL--LLPTYVGVEVLKVSATDPDSE 1914
Query: 130 IPLTVPRGLTIFK-DIRAFDRDK-----PNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+P + L D D + N S HY ++ DG F S+ ++
Sbjct: 1915 VPPELTYSLMEGSLDHFLIDSNSGVLTIKNNNLSKDHYMLIVKVSDGKFY--STSMVTIM 1972
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
+++ +D +G Q S + I ++A+ L L+Y +++ ++
Sbjct: 1973 VKEAMD--SGLHFTQSFYSTSISENNTNITKVAIVNAVGNRLN--EPLKYSILNPGNK-- 2026
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F + S +G + + D E + + L V+AS+ + L+ A+ V + + D+NDN
Sbjct: 2027 FKIKSTSG-VIQTTGVPFDRE---EQELYELVVEASRELDHLRVARVVVRVNIEDINDNS 2082
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
P F Y ++ + G + QV A DKD+G NGE TY L D G F I+P SG
Sbjct: 2083 PVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSG 2138
Score = 78.2 bits (184), Expect = 2e-12
Identities = 103/414 (24%), Positives = 177/414 (42%), Gaps = 39/414 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI----GPSLTIPLTV 134
A + V V IED+NDN P+F+ PY+ V G I+ + I GP+ + +
Sbjct: 2067 ARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPG--TLIYQVTAIDKDKGPNGEVTYVL 2124
Query: 135 PRGLTIFK----DIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHK-PVLLLRKVL 188
F+ ++ N+ S++ Y + + D G +L +S + P+ ++ K +
Sbjct: 2125 QDDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAM 2184
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
DK F ++++I PI +I+ G + Y +I G+ K F++D
Sbjct: 2185 P--VFDKPFYTA------SVNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDF 2236
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL--DLNDNLPEF 306
G L + LD + + + L ++AS + L A+A V ++LL D+NDN P F
Sbjct: 2237 DTGVLKVVSPLDYEV-----TSAYKLTIRAS---DALTGARAEVTVDLLVNDVNDNPPIF 2288
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA---FSIDPRSGW-L 361
+ YN ++ E G VLQV++ D D N YQ+ D + F ID SG L
Sbjct: 2289 DQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLIL 2348
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQPLETNAPLEKTTYV 420
T R +LD E +KV + ++ PS+ I+ P N + ++
Sbjct: 2349 TAR---MLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVS 2405
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK 474
G ++ D F +E ++L ND + S ++ ++ K
Sbjct: 2406 ELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRK 2459
Score = 77.0 bits (181), Expect = 4e-12
Identities = 74/292 (25%), Positives = 132/292 (45%), Gaps = 20/292 (6%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAP-IGPSLTIPLTV 134
+S+ +VT+ + D+NDN P+F Y VTV E T G + +F + IG + I +
Sbjct: 3217 LSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLI 3276
Query: 135 PRGLTIFK---DIRAFDRDKPNTPNSDV---HYSIVSGNDDGHFALESSHKPVLLLRKVL 188
G K + + + ++ Y +V D G AL + + L V
Sbjct: 3277 RSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVN 3336
Query: 189 DYDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D ++ +++ + ++ + A D D + + +++G+ F++D
Sbjct: 3337 DNPPKFSQDVYSAVISEDALVGDSVIL---LIAEDVDSQPNGQIHFSIVNGDRDNEFTVD 3393
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
V G + ++K+LD + + + + L VQA P ++ A V I++ D+NDN P F
Sbjct: 3394 PVLGLVKVKKKLDRE-----RVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFT 3448
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENG---EFTYQLDDPKGAFSIDP 356
Y I EN P G S+LQ++ TD+D NG F+ + + F +DP
Sbjct: 3449 PANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDP 3500
Score = 72.5 bits (170), Expect = 8e-11
Identities = 52/164 (31%), Positives = 80/164 (48%), Gaps = 14/164 (8%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS-QLNNPLKT 287
+T+ E N +F ++ G++ L+K LD + + F +V A+ L+
Sbjct: 2742 STVNGERPENNKGGIFVIEQETGTIKLDKRLDRET-----SPAFHFKVAATIPLDKVDIV 2796
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-- 345
V+I++LDLNDN P FE Y+ I+E +P G + QV A D D G NG+ TY L
Sbjct: 2797 FTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHS 2856
Query: 346 -DDPK---GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
P+ AF+ID +GW++ LD E + V A +
Sbjct: 2857 DSQPEKVMEAFNIDSNTGWISTLKD--LDHETDPTFTFSVVASD 2898
Score = 69.7 bits (163), Expect = 6e-10
Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 6/154 (3%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN-----TFVLQVQASQLNNPL 285
++Y ++SG++ F + V + F + ++ N ++L V+ S L
Sbjct: 80 IKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDL 139
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A +V I++LD+ND P F Y+++I E+ P SV QV ATD D G NGEF Y
Sbjct: 140 E-AWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYF 198
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
+ FS+ P SG +++ + D + L +
Sbjct: 199 KNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEI 232
Score = 69.7 bits (163), Expect = 6e-10
Identities = 56/170 (32%), Positives = 80/170 (47%), Gaps = 10/170 (5%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D A L Y+++ +K F++DS G++ LD H A+ F
Sbjct: 1796 PLVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLD----HETIAH-FHF 1850
Query: 275 QVQASQLNNPLKTAQARVE--IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V +P TA++ VE IE+ D+NDN P F + ++ G VL+V ATD
Sbjct: 1851 HVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATD 1910
Query: 333 KDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
D E TY L + F ID SG LT++N + + H L +KV
Sbjct: 1911 PDSEVPPELTYSLMEGSLDHFLIDSNSGVLTIKNNNL--SKDHYMLIVKV 1958
Score = 69.3 bits (162), Expect = 8e-10
Identities = 141/683 (20%), Positives = 268/683 (39%), Gaps = 97/683 (14%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P+ Y F++ + +V ++G V +V P N + +D+ + S F
Sbjct: 1360 PLTFDEPFYNFTVMESDRVTEIVGVV-SVQP---ANTPLWFDIVGGN---FDSAFDAEKG 1412
Query: 517 TGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
GT+ +A+ E R + + VE +D ++AV + + N + P+F
Sbjct: 1413 VGTIVIAKPLDAEQRSIYNMSVEVTDGT--------NVAVTQVFIK--VLDNNDNGPEFS 1462
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP---FAVEERSGVITV 631
Y+ + +V T + QI D E++ +SY + H + + F ++ +GV+
Sbjct: 1463 QPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTV-HSSIDSISMRKFRIDPSTGVLYT 1521
Query: 632 VDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
+ L + + + QE + V+V D ND + +F +
Sbjct: 1522 AERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVF--ES 1579
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED--GTIFTQKPLDREK 748
+ G+A+ Q+ T + G N + + T ++ E G I K D
Sbjct: 1580 AALGSAVLQV--TALDKDKGE---NAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTT 1634
Query: 749 RDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
+ +++ + + +S I ++++ + D + P F H Y+ + EN IGT +
Sbjct: 1635 MGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSH--PKFIHKDYQAEVNENVDIGTSVI 1692
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
+ + I + L G+ +F ++ +GV+ +LD E+ Y+L + A
Sbjct: 1693 LISAISQS-------TLIYEVKDGDINGIFTINPYSGVIT-TQKALDYERTSSYQLIIQA 1744
Query: 868 RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKF 927
+ G++S A + I I ++EN + ++ +G+ + E P N
Sbjct: 1745 TNMAGMASNATVNIQI------------VDENDNAPVFLFSQYSGS----LSEAAPINSI 1788
Query: 928 ALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALE 987
+D N P+ + A D DS N + Y+
Sbjct: 1789 VRSLD----------NSPL-----VIRATDADSNRNALLVYQIVEST------------- 1820
Query: 988 VKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN----LNDNISVRVFVKDVNDH 1041
K++F ++ G + +L E+ F ++ D G+ + V + V DVND+
Sbjct: 1821 AKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDN 1880
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
PVF + + + Y + KV ATD D LTY + D F I +GV
Sbjct: 1881 PPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSLD-HFLIDSNSGV 1939
Query: 1102 LSVNGELDRETEDKYILTVVARD 1124
L++ + ++D Y+L V D
Sbjct: 1940 LTIKN--NNLSKDHYMLIVKVSD 1960
Score = 68.5 bits (160), Expect = 1e-09
Identities = 102/466 (21%), Positives = 188/466 (40%), Gaps = 50/466 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++ T I+++ A D D ++ Y +S + D++ +++ F I+ G
Sbjct: 1470 ISEDVLPDTEILQIEATDRDE--KHKLSYTVHSSI---------DSISMRK-FRIDPSTG 1517
Query: 1000 HVIVARSLPPESEFR--LNISALDGG-NLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A L E++ + LNI D N++ V V V+D NDH P F Y +V
Sbjct: 1518 VLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVF 1577
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ + +V A D D G+NA L Y I+ +T F+I P+ G++++ E D T +
Sbjct: 1578 ESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQ 1637
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS-PKFYAFDELLEWKHPEADELSNHNFE 1174
++L++ D G ++DNS PKF D E +E +
Sbjct: 1638 FVLSIKVTDQGSPPMSATAIVRISVT--MSDNSHPKFIHKD-----YQAEVNENVDIGTS 1690
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
+++ + ++T+ G N + + Y +R + L + + +
Sbjct: 1691 VILISAISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDY---ERTSSYQLIIQATNM 1747
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEE--NVNAPVELVS-----LNLTEHYEN 1287
+ ++ E + PVF+ Y + E +N+ V + + T+ N
Sbjct: 1748 AGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSN 1807
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
+ + ++ ++ F +D G + + + D E + V R S +L
Sbjct: 1808 -RNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHV-RDSGSPQL--- 1862
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
AE V+V + + DVNDN P FT + +PT
Sbjct: 1863 ---TAES--------PVEVNIEVTDVNDNPPVFTQAVFETILLLPT 1897
Score = 68.1 bits (159), Expect = 2e-09
Identities = 36/105 (34%), Positives = 60/105 (57%), Gaps = 2/105 (1%)
Query: 1022 GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
G +L V + V D+ND P+F T Y+ + E+ R + +V ATDAD G N
Sbjct: 136 GEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFY 195
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
Y+ + + DL F + P +GV+S++G L+ + +++Y L ++A D G
Sbjct: 196 YYFK-NKVDL-FSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRG 238
Score = 67.3 bits (157), Expect = 3e-09
Identities = 81/317 (25%), Positives = 128/317 (40%), Gaps = 25/317 (7%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF--IFLIAPIG 125
+R L A ++V + + DVNDN PIF Y+ T+ E + G + + A
Sbjct: 2259 IRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSE 2318
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDV-------HYSIVSGNDDGHFALESSH 178
+ + + + D D + + H ++ + D F SS
Sbjct: 2319 NNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSE 2378
Query: 179 KPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
VL+ + D + F QL+ + + F + A D D L Y ++S
Sbjct: 2379 --VLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILS 2436
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GNDR F +DS +G + L + H Q + + S +++ L T+ A+V I +L
Sbjct: 2437 GNDRTSFLMDSKSGVITL-------SNHRKQRMEPLYSLNVS-VSDGLFTSTAQVHIRVL 2488
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
N P F Y + EN+ G V+ V ATD D G G+ +Y + D K F ID
Sbjct: 2489 GANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLID 2548
Query: 356 PRSGWLTVRNQTVLDRE 372
+T LDRE
Sbjct: 2549 SNGQVITTER---LDRE 2562
Score = 66.9 bits (156), Expect = 4e-09
Identities = 48/169 (28%), Positives = 80/169 (47%), Gaps = 8/169 (4%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D+ + T+ + S + RK F +D G L+ + LD +A+ + +L +
Sbjct: 1489 DEKHKLSYTVHSSIDSISMRK-FRIDPSTGVLYTAERLDHEAQ-----DKHILNIMVRDQ 1542
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
P + ARV + + D ND+ P F Y S+ E+ G +VLQV A DKD+GEN E
Sbjct: 1543 EFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAEL 1602
Query: 342 TYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
Y ++ + F I+P G +T+ + + L +KV + + P
Sbjct: 1603 IYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPP 1651
Score = 66.1 bits (154), Expect = 7e-09
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 15/183 (8%)
Query: 946 IGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
IGT ++++ ++D DS N + Y+ + Y S D YF I+ G ++ AR
Sbjct: 2303 IGTPVLQVVSIDADSENNKMVHYQIVQDTYN-----STD------YFHIDSSSGLILTAR 2351
Query: 1006 SLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
L E L + ++D G +L+ + V +++ DVND+ PVF + Y V E
Sbjct: 2352 MLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRG 2411
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ V A+DAD L Y I + F + +GV++++ + E Y L V
Sbjct: 2412 HFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVS 2471
Query: 1122 ARD 1124
D
Sbjct: 2472 VSD 2474
Score = 64.5 bits (150), Expect = 2e-08
Identities = 38/115 (33%), Positives = 60/115 (52%), Gaps = 10/115 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y+L G D F ++ +G + + L NT +V ++ N +A
Sbjct: 408 VEYKLSPGEDAVYFKINPRSGLIVTARPL----------NTVKKEVYKLEVTNKEGDLKA 457
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+V I + D ND+ PEF+ Y+ + E++P G SVL V A+DKD+GENG TY +
Sbjct: 458 QVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSI 512
Score = 62.5 bits (145), Expect = 9e-08
Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 11/152 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y +I+ + F +DS NG + + LD E+ L+ + + V+
Sbjct: 2519 VRATDGDPGTYGQISYAIINDFAKDRFLIDS-NGQVITTERLD--RENPLEGDVSIF-VR 2574
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A L+ +T V + ++D NDN P+F Y S+ ++ G V QV A D D G
Sbjct: 2575 A--LDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGA 2632
Query: 338 NGEFTYQLDDPKGA-----FSIDPRSGWLTVR 364
N TY L IDP +GW+ +
Sbjct: 2633 NSRITYSLYSEASVSVADLLEIDPDNGWMVTK 2664
Score = 62.1 bits (144), Expect = 1e-07
Identities = 58/195 (29%), Positives = 82/195 (42%), Gaps = 23/195 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+ GT +I + A D D G GQI Y ++ K F+I+ +G
Sbjct: 2506 VRENVAAGTKVIHVRATDGDPGTYGQISYAIINDF-------------AKDRFLIDS-NG 2551
Query: 1000 HVIVARSL----PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
VI L P E + + + ALDGG +VRV V D ND+ P F Y +V
Sbjct: 2552 QVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVR 2611
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI----QPSDTDLPFEISPLTGVLSVNGELDRE 1111
++ +V A D D G N+ +TY + S DL EI P G + G ++
Sbjct: 2612 ADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADL-LEIDPDNGWMVTKGNFNQL 2670
Query: 1112 TEDKYILTVVARDNG 1126
V A D G
Sbjct: 2671 KNTVLSFFVKAVDGG 2685
Score = 61.7 bits (143), Expect = 2e-07
Identities = 51/163 (31%), Positives = 81/163 (49%), Gaps = 20/163 (12%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIY---QVTIYIEDENDNPPVFEHATYEGFIMENS 800
L+RE +D Y + V KG + G + +V I + D ND P+F TY I E++
Sbjct: 118 LNREIQDNYLLIV-----KGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAEST 172
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
+ T + + ATDAD G+N F Y F ++F V +GV+ G L+ ++K
Sbjct: 173 PLRTSVAQ---VTATDADIGSNGEFYY-YFKNKVDLFSVHPTSGVISLSG-RLNYDEKNR 227
Query: 861 YKLSLVARDTG-------GLSSEAELIIMIGDENDNKPEFNQI 896
Y L ++A D G G+SS A+L + I N++ P + +
Sbjct: 228 YDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVV 270
Score = 61.3 bits (142), Expect = 2e-07
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 14/168 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G A L Y + +GN +F ++ V G + + KE D+ FVL ++
Sbjct: 1589 VTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTT-----MGQFVLSIK 1643
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ +P +A A V I + +++ P+F Y + EN+ G SV+ + A +
Sbjct: 1644 VTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQ---- 1699
Query: 338 NGEFTYQLDDP--KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
Y++ D G F+I+P SG +T Q LD E SS ++ + A
Sbjct: 1700 -STLIYEVKDGDINGIFTINPYSGVIT--TQKALDYERTSSYQLIIQA 1744
Score = 59.3 bits (137), Expect = 8e-07
Identities = 84/338 (24%), Positives = 145/338 (42%), Gaps = 28/338 (8%)
Query: 1011 SEFRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
S ++L I A D ++V + V DVND+ P+F + YN + EA + +V +
Sbjct: 2253 SAYKLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVS 2312
Query: 1070 TDADFGQNANLTYFIQP---SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
DAD N + Y I + TD F I +G++ LD E L V + D+G
Sbjct: 2313 IDADSENNKMVHYQIVQDTYNSTDY-FHIDSSSGLILTARMLDHELVQHCTLKVRSIDSG 2371
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATI 1186
DVNDN P F++L+ + EL+ + +A+
Sbjct: 2372 FPSLSSEVLVHIYIS-DVNDNPP---VFNQLIYESY--VSELAPRGH----FVTCVQASD 2421
Query: 1187 EENAPIGTTVAKVFA-ND-TDFIGNG-NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
+++ + + ND T F+ + +G+I S +++ + L ++S + L + A
Sbjct: 2422 ADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTA 2481
Query: 1244 DVPDEVEMSD--KPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYYILNEND 1299
V V ++ P F Y E+ ENV A +++ + T+ ++ Y I+N+
Sbjct: 2482 QVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFA 2541
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDRE--VKDTYEVIVRA 1335
D F+ID NG + DRE ++ + VRA
Sbjct: 2542 KD---RFLID-SNGQVITTERLDRENPLEGDVSIFVRA 2575
Score = 58.8 bits (136), Expect = 1e-06
Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 15/177 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGND----RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ AID D G + Y L S + + F++DS G + K+LD + + TF
Sbjct: 2837 VRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDP-----TFT 2891
Query: 274 LQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V AS L ++ A V + + D+NDN P F + Y ++ E+ P G V + D
Sbjct: 2892 FSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWD 2951
Query: 333 KDQGE-NGEFTYQL--DDPKGAFSID-PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+D + N + +Y + +P+G F++ +S W V + LDRE + + A +
Sbjct: 2952 RDTSDVNRQVSYHITGGNPRGRFALGLVQSEW-KVYVKRPLDREEQDIYFLNITATD 3007
Score = 55.6 bits (128), Expect = 1e-05
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+TL YE+ G+ +F+++ +G + +K LD + + +++ L +QA+ + +
Sbjct: 1700 STLIYEVKDGDINGIFTINPYSGVITTQKALDYE-----RTSSYQLIIQATNMAG--MAS 1752
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGF------SVLQVMATDKDQGENGEF 341
A V I+++D NDN P F Y+ S+ E P N S L + ATD D N
Sbjct: 1753 NATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALL 1812
Query: 342 TYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
YQ+ K F++D +G +R LD E + V+ +++
Sbjct: 1813 VYQIVESTAKKFFTVDSSTG--AIRTIANLDHETIAHFHFHVHVRDS 1857
Score = 52.4 bits (120), Expect = 9e-05
Identities = 78/342 (22%), Positives = 133/342 (38%), Gaps = 44/342 (12%)
Query: 77 ISAYLSVTVYIE--DVNDNVPIFLDTPYHVTVDELTP---------------TGEKAFIF 119
+ Y ++ VYIE DVNDN P+ + Y+ V E +P + + +
Sbjct: 1127 VPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTY 1186
Query: 120 LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
I P + + GL I R DR++ H+ V+ D G +S+
Sbjct: 1187 RITSGNPQNFFAINIKTGL-ITTTSRKLDREQQAE-----HFLEVTVTDGGPSPKQST-- 1238
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIH---AIDQDLGVGATLRYELI 236
+ ++ +VLD + +F + EPI+ A D+D G A + Y ++
Sbjct: 1239 -IWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIV 1297
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
GND F +D G + K+ + +L ++A P K++ AR+ IE
Sbjct: 1298 DGNDDGKFFIDPKTGMVSSRKQFTAGSYD-------ILTIKAVDNGRPQKSSTARLHIEW 1350
Query: 297 LDLNDNLP---EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFS 353
+ P F+ FYN +++E+ V +++ Q N + + +
Sbjct: 1351 IKKPPPSPIPLTFDEPFYNFTVMES----DRVTEIVGVVSVQPANTPLWFDIVGGNFDSA 1406
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTF 394
D G T+ LD E S M V + TN +V F
Sbjct: 1407 FDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVF 1448
Score = 51.6 bits (118), Expect = 2e-04
Identities = 79/340 (23%), Positives = 140/340 (41%), Gaps = 36/340 (10%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-FAVEERSGVI 629
P F Y + + + TSV Q+ DA ++ + + ++ V F+V SGVI
Sbjct: 157 PLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEF--YYYFKNKVDLFSVHPTSGVI 214
Query: 630 TVVDDLSRYNRPMYDFEAVA------LQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
++ L+ + YD E +A L N +S VH+ +N+ + H P
Sbjct: 215 SLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVP 274
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG------T 737
F +++ A + + + G + + D D +A++G
Sbjct: 275 --FSLEKEPTYAVV------TVDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYK 326
Query: 738 IFTQKPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV-FEHATYEGF 795
I +K +D E Y +T+ A+ +KG + D P+ FE Y+
Sbjct: 327 IKERKQIDWESFPYGYNLTLQAK-DKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVS 385
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I E S G + I+K + E + + + GE F ++ +G++ L+
Sbjct: 386 ISEFSPPGVVVA---IVKL--SPEPIDVEYKLSP-GEDAVYFKINPRSGLI-VTARPLNT 438
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
KK +YKL + ++ G L +A++ I I D ND+ PEF Q
Sbjct: 439 VKKEVYKLEVTNKE-GDL--KAQVTISIEDANDHTPEFQQ 475
Score = 50.8 bits (116), Expect = 3e-04
Identities = 53/194 (27%), Positives = 93/194 (47%), Gaps = 21/194 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I E+ +G ++I L A D+DS NGQI + S ++ D F ++
Sbjct: 3350 VISEDALVGDSVILLIAEDVDSQPNGQIHF----------SIVNGDR---DNEFTVDPVL 3396
Query: 999 GHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G V V + L E S + L + A+D G ++ +V + + DVND+ PVF Y +
Sbjct: 3397 GLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVI 3456
Query: 1055 EEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+E + + ++ TD D F ++ I + + F + P G+L + + + TE
Sbjct: 3457 QENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDP-HGILR-SAVVFQHTE 3514
Query: 1114 D-KYILTVVARDNG 1126
+Y+L V A+D+G
Sbjct: 3515 SLEYVLCVQAKDSG 3528
Score = 49.2 bits (112), Expect = 9e-04
Identities = 72/313 (23%), Positives = 131/313 (41%), Gaps = 20/313 (6%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ VRV ++D+ND+ PVF Y V+ ++ +V A D D G N +TY +Q D
Sbjct: 2069 VVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQ--D 2126
Query: 1089 TDLPFEISPLTGVLSVNGELDRETED-KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
FEI+P +G + + + + + +Y +T++A+D G
Sbjct: 2127 DYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPV 2186
Query: 1148 SPK-FY--AFDELLEWKHPEAD-ELSNHNFESVMMIPVYKATIEE-NAPIGTTVAKVFAN 1202
K FY + +E + P ++ + ++ I + ++ N T V KV +
Sbjct: 2187 FDKPFYTASVNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKV-VS 2245
Query: 1203 DTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY 1262
D+ Y L R + G + + +L V DV D + D+P + +
Sbjct: 2246 PLDY----EVTSAYKLTIRASDALTGARAEVTVDLL---VNDVNDNPPIFDQPTYNTTLS 2298
Query: 1263 ELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
E + + PV L +++ EN KM +Y + ++ + F ID +G + R D
Sbjct: 2299 EASL---IGTPV-LQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLD 2354
Query: 1323 REVKDTYEVIVRA 1335
E+ + VR+
Sbjct: 2355 HELVQHCTLKVRS 2367
Score = 48.8 bits (111), Expect = 0.001
Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E L ++ V + +LD ND P+F P+ Y ++ + + T + +V A D D+G NG
Sbjct: 137 EDLEAWTKVNIQVLDMNDLRPLFSPTT-YSVTIAESTPLRTSVAQVTATDADIGSNGEFY 195
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVA 523
Y + +L F ++P +G +S++
Sbjct: 196 YYFKNKVDL-----FSVHPTSGVISLS 217
Score = 40.3 bits (90), Expect = 0.40
Identities = 52/190 (27%), Positives = 78/190 (41%), Gaps = 23/190 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I EN P+GT+I++L D DS NG PP S + + FV+ + H
Sbjct: 3455 VIQENKPVGTSILQLVVTDRDSFHNG------------PPFSFSILSGNEEEEFVL-DPH 3501
Query: 999 G--HVIVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G V E+ L + A D G + +RV V + + H P
Sbjct: 3502 GILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVT 3561
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + V+GK+ ATD D LT+ ++ L F+++ G + G LD
Sbjct: 3562 MEDDFPGGVIGKIHATDQDMYD--VLTFALKSEQKSL-FKVNSHDGKIIALGGLD---SG 3615
Query: 1115 KYILTVVARD 1124
KY+L V D
Sbjct: 3616 KYVLNVSVSD 3625
Score = 39.9 bits (89), Expect = 0.53
Identities = 53/237 (22%), Positives = 96/237 (40%), Gaps = 24/237 (10%)
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKI 513
D P+ +Y+ S+ + G V+ VK + V Y L + FKI
Sbjct: 371 DTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID----VEYKLSPGEDAVY---FKI 423
Query: 514 NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
NP +G + A + +E +++ + A VTI + + P+F
Sbjct: 424 NPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLK------AQVTISI----EDANDHTPEF 473
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
Y+ +V +V +GTSV + + D E ++Y + +PF + + +GVI+
Sbjct: 474 QQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSI--ASLNLLPFVINQFTGVIST 531
Query: 632 VDDLSRYNRP-MYDFEAVALQENA--NLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
++L + P +Y F A + N T+ + +VND + K A +I
Sbjct: 532 TEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVI 588
Score = 37.1 bits (82), Expect = 3.7
Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 992 FVINERHGHVIVA--RSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F+++ + G + ++ R E + LN+S DG V + V N + P F ++
Sbjct: 2443 FLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDG-LFTSTAQVHIRVLGANLYSPAFSQST 2501
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y V E + V ATD D G ++Y I F I G + LD
Sbjct: 2502 YVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDS-NGQVITTERLD 2560
Query: 1110 RET--EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
RE E + V A D G D NDN+P+F
Sbjct: 2561 RENPLEGDVSIFVRALDGG---GRTTFCTVRVIVVDENDNAPQF 2601
Score = 36.7 bits (81), Expect = 4.9
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
A D+DIG N IRY + F +DP SG ++ +A L R+
Sbjct: 3054 AKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRE 3095
Score = 36.3 bits (80), Expect = 6.5
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 1443 DSDIGINADIRYQILNEQAPRFAIDPVSGTVRV 1475
D D+G+ +RY ++N+ RF ID SG +R+
Sbjct: 963 DPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRL 995
Score = 36.3 bits (80), Expect = 6.5
Identities = 15/44 (34%), Positives = 24/44 (54%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ +G+ +S+ +V + I DVNDN P+F Y + E P G
Sbjct: 3420 VDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVG 3463
Score = 36.3 bits (80), Expect = 6.5
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 8/103 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q +S + V +++ + + P +P ++ +M+ + G VIGK+ A D D+ ++ +
Sbjct: 3531 QQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFP-GGVIGKIHATDQDM--YDVLTF 3587
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD 540
L+ S FK+N + G + +A + G++ L V SD
Sbjct: 3588 ALKSEQK----SLFKVNSHDGKI-IALGGLDSGKYVLNVSVSD 3625
>UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 2058
Score = 195 bits (475), Expect = 9e-48
Identities = 190/652 (29%), Positives = 305/652 (46%), Gaps = 62/652 (9%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK-- 349
V I + D+NDN P F Y ++EN P G VL+V A+D+DQG NG+ TY+L +
Sbjct: 906 VVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKD 965
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQ-- 406
AFSI+ +G +TV V+DREA + + V A++ PS TFA+ K
Sbjct: 966 DAFSINNVTGEITVAG--VIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNF 1023
Query: 407 ----------PLETNAPLEKTTYVFPD-KVGTKTENIEYYDEQLMSFVNVE----VTLLD 451
+ N+P+ T + PD K+ + T + + +TL+
Sbjct: 1024 PQFSFTGYEGEIAENSPVGSTITMVPDQKISSSTLRPRSSPRAPAALLTAREKRPITLI- 1082
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
ND +P+F S +Y ++ +A G VIG+V A D D G N ++ Y S+ + F
Sbjct: 1083 -NDESPLFEKS-MYYVNVSESASRGIVIGRVTATDRDEGINAIIFY-----SSNGAEAKF 1135
Query: 512 KINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
++ +TG + + +SP+ + + L V A++ A + + + +V
Sbjct: 1136 YVSRSTGDI-IVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVI-------D 1187
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGV 628
D P F + + N IGT+V +I D + +SY + +G G+ F ++ +G
Sbjct: 1188 DKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGL-FTIDNVTGE 1246
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANL-SIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
I V +L R N Y+ V +++ NL S + V V DVND V ++ I +
Sbjct: 1247 IRTVAELDRENVTQYEL-FVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYT--IEY 1303
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTI-FTQKPLD 745
+E+ G +I Q+ +I + N L + ++VTD + + A G I LD
Sbjct: 1304 WEESPEGTSILQV-----KAIDADIGDNAAVLYSIVENVTDYVTVNAITGVISLGSSQLD 1358
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE + + T+ A + GV S + V I + D NDN PVF + Y ++ EN GT
Sbjct: 1359 REVEEYFNFTIRAT-DSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTP 1417
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ ++ A+D D GTNA Y L G F +D +TG + + L+RE+ Y L+L
Sbjct: 1418 VL---VVTASDKDVGTNAKLSYVLSGVLYTRFAIDPDTGNIT-TREPLNREETGSYTLTL 1473
Query: 866 VARDTGGLSSE--AELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
A D+ + E +II + D ND+ P+F Q VR + K+ T G
Sbjct: 1474 RAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVR--EDVKVGHTVG 1523
Score = 179 bits (436), Expect = 5e-43
Identities = 262/1021 (25%), Positives = 423/1021 (41%), Gaps = 137/1021 (13%)
Query: 423 DKVGTKTENIEYYDEQLMS---FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI 479
+ + T T + YD + S V + V +LD NDN P ++ A GTV+
Sbjct: 559 ETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVL 618
Query: 480 -GKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALF 535
+ AVDPD G NG + Y + S F +N TG + ++ + + L+ + L
Sbjct: 619 LSSIAAVDPDAGSNGQLTYSMSGGD-----SRFTLNSATGRLQISPTGLDRELKDSYDLI 673
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG-IGTSVGQ 594
+ +D + P+ ++ V ++V T P+ P A Y V G I ++
Sbjct: 674 INVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPN-PAQSLATYVITVDEGPGTINKTLID 732
Query: 595 IRVND--AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
I D A V+Y L G E G F ++ +G ++V +L R + P A Q
Sbjct: 733 INATDPDADANGKVAYSL-SGDEHGF-FRLDPVTGELSVRKELDRES-PQMSRNA---QG 786
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG 712
+ + AT ++D + ++ S + +NS Q + T +S G
Sbjct: 787 DGRFLLDITATDQATPISDRKSATVRV--SITVRDTNDNSPQFQ-SQNYETRLSEAARPG 843
Query: 713 TGNVRFLIANQQD------VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
+ NV + A QD V +I ++ + L R + V+ + +K +
Sbjct: 844 S-NVIQVSATDQDLEYKGKVIYNITDGDENRKCEVEKLVRHYNWHKKNCVLCKESKCSVE 902
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
V IY++D NDN PVF + Y ++ENS GT + + A+D D+G N
Sbjct: 903 RT---YVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLR---VHASDRDQGANGKIT 956
Query: 827 YTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE---AELIIM 882
Y L K+ F ++ TG + G +DRE + L++ A D G SS AE++I
Sbjct: 957 YKLTNGNKDDAFSINNVTGEITVAG-VIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVIT 1015
Query: 883 IGDENDNKPEFN------QIEENSKV----------RIHRET---KLNGTAGFTIIEVKP 923
+ DENDN P+F+ +I ENS V +I T + + A ++ +
Sbjct: 1016 VKDENDNFPQFSFTGYEGEIAENSPVGSTITMVPDQKISSSTLRPRSSPRAPAALLTARE 1075
Query: 924 KNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
K L D+ PLF + E+ G I ++ A D D G+N I Y
Sbjct: 1076 KRPITLINDE-SPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFY-------- 1126
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD--GGNLNDNISVR 1032
S++ E K F ++ G +IV L E + + LN++A + G + V
Sbjct: 1127 -----SSNGAEAK--FYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVH 1179
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
+ V DV D P F + + E + K+ A D D G ++Y I D
Sbjct: 1180 ITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSIANGDPYGL 1237
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F I +TG + ELDRE +Y L V A+D+ DVNDN P F
Sbjct: 1238 FTIDNVTGEIRTVAELDRENVTQYELFVQAKDS--VNLVSDLLKVVVQVEDVNDNPPVFS 1295
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK-----VFAND-TDF 1206
+E+ E+ E + S++ + A I +NA + ++ + V N T
Sbjct: 1296 MPGYTIEYWE-ESPEGT-----SILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAITGV 1349
Query: 1207 IGNGNGLILYSLPQRKN----QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY 1262
I G+ + + + N + G+PS SSTA + + + D+ D + PVF + Y
Sbjct: 1350 ISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDIND-----NSPVFNNTDY 1404
Query: 1263 ELEIEENVNA--PVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRS 1320
+ EN A PV +V+ + + N K+ Y + T F IDP G +
Sbjct: 1405 YAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT----RFAIDPDTGNITTREP 1460
Query: 1321 PDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+RE +Y + +RA A EG T+ V++ + D ND+ P+F
Sbjct: 1461 LNREETGSYTLTLRAVDS-------------AIRAREGTTR----VIITVTDANDHVPQF 1503
Query: 1381 T 1381
T
Sbjct: 1504 T 1504
Score = 160 bits (389), Expect = 2e-37
Identities = 239/988 (24%), Positives = 391/988 (39%), Gaps = 133/988 (13%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN+PVF S Y + N+ GT + +V A D D G NG + Y L +N
Sbjct: 912 DVNDNDPVFNQSK-YAADVLENSPTGTPVLRVHASDRDQGANGKITYKL---TNGNKDDA 967
Query: 511 FKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F IN TG ++VA E H L V+A DQ S + ++ V+T+ K
Sbjct: 968 FSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITV------KDEND 1021
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV---EER 625
+ P F YE + N +G+++ + +Q S L P A+ E+
Sbjct: 1022 NFPQFSFTGYEGEIAENSPVGSTITMVP-----DQKISSSTLRPRSSPRAPAALLTAREK 1076
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVNDERGVLLKGAHSPI 684
+ + D+ + + MY V + E+A+ IV T D + +
Sbjct: 1077 RPITLINDESPLFEKSMY---YVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGAEA 1133
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPL 744
F+V ++ + ++Y ++A QD T + I I KP
Sbjct: 1134 KFYVSRSTGDIIVDSPLDREFKNVYILNVTAAN-IVAGAQDTTTQVHITVTDVI-DDKPY 1191
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND--NPPVFEHATYEGFIMEN--S 800
+TV N + G + ++T +D D + + Y F ++N
Sbjct: 1192 FNSSS----LTVKLSENASI--GTNVTKITALDKDIGDTISYSIANGDPYGLFTIDNVTG 1245
Query: 801 KIGT--EIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKFIGDSLDREK 857
+I T E+ +N+ + + +++ + + L ++ DV++N V G +++ +
Sbjct: 1246 EIRTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWE 1305
Query: 858 KIMYKLSL--VARDTGGLSSEAELIIMIGDENDNKPEFNQIEE-----NSKVRIHRETKL 910
+ S+ V + A ++ I + + N I +S++ E
Sbjct: 1306 ESPEGTSILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAITGVISLGSSQLDREVEEYF 1365
Query: 911 NGTAGFTIIEVKPKNKFA------LDVDQLGPLF-------LIPENIPIGTTIIKLNALD 957
N T T V K+ A +D++ P+F + EN P GT ++ + A D
Sbjct: 1366 NFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASD 1425
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRL 1015
D G N ++ Y + +Y F I+ G++ L E + L
Sbjct: 1426 KDVGTNAKLSYVLSGVLYTR--------------FAIDPDTGNITTREPLNREETGSYTL 1471
Query: 1016 NISALDGGNLNDNISVRVF--VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
+ A+D + RV V D NDH P F ++ Y F+V E +G+V TD D
Sbjct: 1472 TLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDED 1531
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
NA + Y+I +T L F ++ TG++S LDRE Y L + A+D+G
Sbjct: 1532 INDNARVRYYISSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHG-IPALES 1590
Query: 1134 XXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG 1193
DVNDN P F K L F ++ V +E A G
Sbjct: 1591 NTSVMITIEDVNDNKPLFS--------KSVYNVTLRESVFLKTQVVQVIATDPDEGAN-G 1641
Query: 1194 TTVAKVFANDTD---FIGNGNGLI------------LYSLPQRKNQQNLGLPSLSSTAIL 1238
K+ A DTD +I GLI LY+L + Q+LG P L+ +
Sbjct: 1642 QFTYKITAGDTDDVFYIDANTGLITIKAKLDYEKTSLYNL--TVSAQDLGTPPLTGACFV 1699
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYILN 1296
+ V+DV D + PVF Y E+ ENV ++++N T + + K YY +
Sbjct: 1700 EIHVSDVDD-----NAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIE 1754
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVRSP----DREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
+TD F+I ++G + L +P +RE YE+ V A + E
Sbjct: 1755 SGNTD--SMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTE--------- 1803
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
K V V+ + DVNDN+P+F
Sbjct: 1804 -------QKSLVPAVITVLDVNDNAPRF 1824
Score = 148 bits (359), Expect = 1e-33
Identities = 193/724 (26%), Positives = 307/724 (42%), Gaps = 99/724 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+G+ + YE+ISGN +F++DS G + + +D + + + F + V+
Sbjct: 175 VEARDGDVGINNPILYEIISGNSDGVFTIDSNTGVITVNGSIDAE-----KTDVFRITVK 229
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN--LPNGFSVLQVMATDKDQ 335
AS++ +P V + ++D+NDN P F Y + E+ LP Q+ TD D
Sbjct: 230 ASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGD- 288
Query: 336 GENGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+N F L GA F+IDP SG L + N+T LD Y K+ N
Sbjct: 289 -KNPVFRRVLYHLVGADSDKFAIDPTSGTLYI-NKT-LD-----------YEKQIN---- 330
Query: 392 GTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLD 451
TF + + E+ V T+T+ E + +V +TL++
Sbjct: 331 FTFDWERGCGSGGGSGWDWTGRGEEKKVV-----ATETDTSEKFSAN----ASVTLTLIN 381
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
NDN P+F S+ Y ++M GT I + A D DLG G + Y+L+ + F
Sbjct: 382 VNDNKPMFAKSS-YNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQ----AAYF 436
Query: 512 KINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP 571
+N + GT+S A+ IL+ + S + +A+ T+ VT + + P
Sbjct: 437 SVNADNGTISAAQ--ILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVT--LQDVNDNDP 492
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVI 629
+F G PY + N+ GT V Q+ D+ E +S+++ G ++G F++ SG++
Sbjct: 493 EFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAG-DDGGHFSI-NGSGLV 550
Query: 630 TVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
T +L R Y A ++ TV+V+D ND + G I ++
Sbjct: 551 TTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGL--TITTNI 608
Query: 689 KENSAG--------AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
E + G AA+ +N Y G+ RF + T + I+ G
Sbjct: 609 SEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTL---NSATGRLQISPTG---- 661
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH------ATYEG 794
LDRE +D Y + +I + G V + I D NDN P F+ ATY
Sbjct: 662 ---LDRELKDSYDL-IINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATY-- 715
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
I + GT K I ATD D N Y+L G+ F +D TG + + LD
Sbjct: 716 VITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGELS-VRKELD 774
Query: 855 REKKIM---------YKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEFNQIEENS 900
RE M + L + A D + S+ + I + D NDN P+F +N
Sbjct: 775 RESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQ--SQNY 832
Query: 901 KVRI 904
+ R+
Sbjct: 833 ETRL 836
Score = 135 bits (326), Expect = 1e-29
Identities = 132/488 (27%), Positives = 211/488 (43%), Gaps = 39/488 (7%)
Query: 443 VNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ V V + D NDN PVF +P E+ +S GT I +VKA+D D+G N VLY +
Sbjct: 1278 LKVVVQVEDVNDNPPVFSMPGYTIEYWEESPE--GTSILQVKAIDADIGDNAAVLYSIVE 1335
Query: 502 TSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+T +N TG +S+ S + +E + A+D S+A+ ++
Sbjct: 1336 N----VTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVD 1391
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ + P F Y +V N GT V + +D + +
Sbjct: 1392 INDNS-------PVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT 1444
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLL 677
FA++ +G IT + L+R Y A+ T + V D ND
Sbjct: 1445 RFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFT 1504
Query: 678 KGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ ++ F V+E+ G +G++ T+ N VR+ I++ G
Sbjct: 1505 QSGYA---FSVREDVKVGHTVGRVATTDEDI---NDNARVRYYISSGNTSLMFSVNETTG 1558
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T LDRE+ Y + + A+ + G+ + V I IED NDN P+F + Y +
Sbjct: 1559 IISTTSTLDREQNASYTLIITAK-DHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTL 1617
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDR 855
E+ + T++ + ATD DEG N F Y + G+ ++F +D NTG++ I LD
Sbjct: 1618 RESVFLKTQVVQ---VIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLIT-IKAKLDY 1673
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
EK +Y L++ A+D G L+ + I + D +DN P F+ K R E N T
Sbjct: 1674 EKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFH------KPRYSAELYENVT 1727
Query: 914 AGFTIIEV 921
G +I V
Sbjct: 1728 RGHHVITV 1735
Score = 126 bits (304), Expect = 5e-27
Identities = 203/863 (23%), Positives = 339/863 (39%), Gaps = 86/863 (9%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF-AVEERSG 627
P F PY + N +GT++ +I DA + V Y + PF ++ +G
Sbjct: 44 PVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNG 103
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+T+ L Y +A E+ + + + T +++V D + + S F+
Sbjct: 104 ELTLGGPLDFEVARSYMLVVIA--EDLGVPKLESRTTVIIEVTDISDMPPRFLQS---FY 158
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
+KE IG T + G N + +I+ D I + G I +D
Sbjct: 159 LKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGVFTID-SNTGVITVNGSID 217
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
EK DV+R+TV A S + V + + D NDN P F + Y + E+ +
Sbjct: 218 AEKTDVFRITVKASEVPDPNSNTTV-TVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGR 276
Query: 806 IKMDNIIKATDADEGTNALF---MYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
+ D + + TD D+ N +F +Y L G + F +D +G + +I +LD EK+I +
Sbjct: 277 VVSDQL-QVTDGDK--NPVFRRVLYHLVGADSDKFAIDPTSGTL-YINKTLDYEKQINFT 332
Query: 863 LSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
G S + G + K + + + K N + T+I V
Sbjct: 333 FDWERGCGSGGGSGWD---WTGRGEEKKVVATETDTSEKF------SANASVTLTLINVN 383
Query: 923 PKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
NK + + E I GT I + A D D G G + YE
Sbjct: 384 D-NKPMFAKSSYN--YTMDEEITPGTHIADITATDADLGTFGALTYELRGGQ-------- 432
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNIS---VRVFVKD 1037
YF +N +G + A+ L ++ +++ ++ DGG I+ V V ++D
Sbjct: 433 ------AAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQD 486
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND+ P F Y ++ E ++ +V ATD D G+N L++ I D F I+
Sbjct: 487 VNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSING 546
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
+G+++ ELDRET Y LTV A D+G D NDN+P+ D L
Sbjct: 547 -SGLVTTARELDRETIATYTLTVSAYDHG-VSSRHKHVQLTVNVLDENDNTPQI--TDGL 602
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILY 1216
+S +++ A + G + D+ F + + G +
Sbjct: 603 -----TITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQI 657
Query: 1217 SLP----QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYEL 1264
S + K+ +L G P +++ + VT+ DV D D P Y +
Sbjct: 658 SPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVI 717
Query: 1265 EIEENVNA-PVELVSLNLT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
++E L+ +N T + N K+ Y + D F +DP G L + +
Sbjct: 718 TVDEGPGTINKTLIDINATDPDADANGKVAYSL----SGDEHGFFRLDPVTGELSVRKEL 773
Query: 1322 DREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
DRE + Q R L + + V+V + ++D NDNSP+F
Sbjct: 774 DRESPQ-----MSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQ 828
Query: 1382 NGNRPLVTAIPTTAPFGYQVMQL 1404
+ N T + A G V+Q+
Sbjct: 829 SQN--YETRLSEAARPGSNVIQV 849
Score = 122 bits (295), Expect = 6e-26
Identities = 125/463 (26%), Positives = 200/463 (43%), Gaps = 38/463 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+ DAND+ P F S Y FS++ + KVG +G+V D D+ N V Y + + N
Sbjct: 1489 VIITVTDANDHVPQFTQSG-YAFSVREDVKVGHTVGRVATTDEDINDNARVRYYIS-SGN 1546
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
++ F +N TG +S + E + L + A D E S+ ++TIE
Sbjct: 1547 TSLM--FSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSV-MITIEDVND 1603
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
K P F + Y + +V + T V Q+ D E +Y + G + V F
Sbjct: 1604 NK------PLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDV-F 1656
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLK 678
++ +G+IT+ L +Y+ V+ Q+ L+ +HV DV+D V K
Sbjct: 1657 YIDANTGLITIKAKLDYEKTSLYNL-TVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHK 1715
Query: 679 GAHSPIIF-------HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+S ++ HV +A + H + +G + FLI Q V +
Sbjct: 1716 PRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVIT-LN 1774
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G L+RE Y + V A + + I + D NDN P F+ +
Sbjct: 1775 CTPSGC------LNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSES 1828
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIG 850
Y ++E++ T+ + +KA D DEG + ++T+ G +F +D TGV+
Sbjct: 1829 YVRSVLEDTGPITDATI-LTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRT- 1886
Query: 851 DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LDRE Y L ++A D G LSS + I + D NDN P
Sbjct: 1887 RPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLP 1929
Score = 111 bits (266), Expect = 2e-22
Identities = 121/440 (27%), Positives = 190/440 (43%), Gaps = 46/440 (10%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
II V N Q G F + E++ +G T+ ++ D D N ++RY YI
Sbjct: 1490 IITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRY------YIS 1543
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRV 1033
S F +NE G + +L E + + L I+A D G L N SV +
Sbjct: 1544 SGNTSL-------MFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMI 1596
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
++DVND+ P+F K+ YN + E+ + + + +V ATD D G N TY I DTD F
Sbjct: 1597 TIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVF 1656
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
I TG++++ +LD E Y LTV A+D G DV+DN+P F+
Sbjct: 1657 YIDANTGLITIKAKLDYEKTSLYNLTVSAQDLG-TPPLTGACFVEIHVSDVDDNAPVFH- 1714
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNG 1210
K + EL + +I V I+ A ++ + +TD IG
Sbjct: 1715 -------KPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQ 1767
Query: 1211 NGLI-LYSLPQR-KNQQNLGLPSLSSTAILMVTVAD----VPDEVEMSD----KPVFISR 1260
+G+I L P N++ L AI V + + VP + + D P F S
Sbjct: 1768 SGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSE 1827
Query: 1261 YYELEIEEN----VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
Y + E+ +A + V + E+ ++ + I++ N+ + F +D + G L
Sbjct: 1828 SYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGV---FQMDNKTGVLT 1884
Query: 1317 LVRSPDREVKDTYEVIVRAE 1336
R DRE Y ++V AE
Sbjct: 1885 RTRPLDREDTSFYSLVVMAE 1904
Score = 109 bits (263), Expect = 4e-22
Identities = 131/481 (27%), Positives = 196/481 (40%), Gaps = 44/481 (9%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN PVF Y + NA+VGT I K+ A+D D G N V Y + T T
Sbjct: 38 DYNDNAPVFTEQP-YMAKIAENARVGTTILKISAIDADSGTNSQVQYKFS-NATATQTPF 95
Query: 511 FKINPNTGTVSVAESPILE-GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPD 569
F +N G +++ E R + V ++ P + S V IEVT + P
Sbjct: 96 FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVP--KLESRTTVIIEVT--DISDMP- 150
Query: 570 IPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
P F+ + Y + N IG++V + R D N + Y+++ G +GV F ++ +G
Sbjct: 151 -PRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGV-FTIDSNTG 208
Query: 628 VITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
VITV + ++ A + + N + V VVDVND R L+ + IF
Sbjct: 209 VITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVY---IF 265
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV-TDDIAI-AEDGTIFTQKPL 744
V+E+ A G++ + G+ R ++ + +D AI GT++ K L
Sbjct: 266 DVREDV--ALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSDKFAIDPTSGTLYINKTL 323
Query: 745 DREKRDVYRMTVIAEFNKGVISG---AGIYQVTIYIEDENDNPPVFEHATYEGFIMEN-- 799
D EK+ + G SG G + + E D F + N
Sbjct: 324 DYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVN 383
Query: 800 ------SKIGTEIKMDNII---------KATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
+K MD I ATDAD GT Y L G F V+ + G
Sbjct: 384 DNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQAAYFSVNADNG 443
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSE---AELIIMIGDENDNKPEFNQIEENSK 901
+ LD + Y+ SLV +D GG E A + + + D NDN PEF + S
Sbjct: 444 TIS-AAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSD 502
Query: 902 V 902
+
Sbjct: 503 I 503
Score = 99.1 bits (236), Expect = 8e-19
Identities = 85/334 (25%), Positives = 149/334 (44%), Gaps = 25/334 (7%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLT 129
+G+ S+ SV + + D+NDN P+F +T Y+ V E P G + + +G +
Sbjct: 1374 SGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAK 1433
Query: 130 IPLTVPRGL----TIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
+ + L I D +P Y++ + D A E + + ++ +
Sbjct: 1434 LSYVLSGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITV 1493
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDR 241
DA D Q + +++ + + D+D+ A +RY + SGN
Sbjct: 1494 T-----DANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTS 1548
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
+FS++ G + LD E N ++ L + A P + V I + D+ND
Sbjct: 1549 LMFSVNETTG--IISTTSTLDREQNA---SYTLIITAKDHGIPALESNTSVMITIEDVND 1603
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
N P F YN+++ E++ V+QV+ATD D+G NG+FTY++ D F ID +G
Sbjct: 1604 NKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTG 1663
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVG 392
+T++ + LD E S + V A++ P + G
Sbjct: 1664 LITIKAK--LDYEKTSLYNLTVSAQDLGTPPLTG 1695
Score = 92.3 bits (219), Expect = 9e-17
Identities = 100/420 (23%), Positives = 181/420 (43%), Gaps = 42/420 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++ + T ++++ A D D G NGQ Y+ + D +V F I+ G +
Sbjct: 1619 ESVFLKTQVVQVIATDPDEGANGQFTYKITA----------GDTDDV---FYIDANTGLI 1665
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ L E S + L +SA D G L V + V DV+D+ PVF K Y+ + E
Sbjct: 1666 TIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYEN 1725
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYF-IQPSDTDLPFEISPLTGVLSVN----GELDRET 1112
+ V+ATD D + Y+ I+ +TD F I +GV+++N G L+RET
Sbjct: 1726 VTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRET 1785
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+Y L V A DVNDN+P+F + + ++
Sbjct: 1786 HARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRF----DSESYVRSVLEDTGPIT 1841
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ-------- 1224
+++ + E+ I T+ N + N G++ + P +
Sbjct: 1842 DATILTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVV 1901
Query: 1225 --QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFI---SRYYELEIEENVNAPVELVSL 1279
++ G P+LSS+ + +TV D+ D + + P+ + R ++EN++A V V +
Sbjct: 1902 MAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVP-VGV 1960
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ + + YY + +T+ ++ F+++ +G L + DRE + + V+A K
Sbjct: 1961 VAAQDLDTKNLIYYYIT--NTEEQKYFILNETSGELRTRITLDREDSSVHYLYVKASNDK 2018
Score = 83.4 bits (197), Expect = 4e-14
Identities = 83/308 (26%), Positives = 137/308 (44%), Gaps = 31/308 (10%)
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL 1091
+ V D ND+ PVF + Y + E + K+ A DAD G N+ + Y F + T
Sbjct: 34 LIVDDYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATATQT 93
Query: 1092 P-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
P F ++ + G L++ G LD E Y+L V+A D G D++D P+
Sbjct: 94 PFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLG-VPKLESRTTVIIEVTDISDMPPR 152
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
F L + E +E + +V+ + + N PI + ++ I +
Sbjct: 153 F-----LQSFYLKEIEE-NTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGVFTIDSN 206
Query: 1211 NGLILY--SLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
G+I S+ K + P+ ++T ++VTV DV D ++P F+
Sbjct: 207 TGVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVND-----NRPAFLQS 261
Query: 1261 YYELEIEENVNAPVELVS--LNLTEHYEN--FKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
Y ++ E+V P +VS L +T+ +N F+ Y L D+D F IDP +GTLY
Sbjct: 262 VYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSD---KFAIDPTSGTLY 318
Query: 1317 LVRSPDRE 1324
+ ++ D E
Sbjct: 319 INKTLDYE 326
Score = 82.2 bits (194), Expect = 1e-13
Identities = 94/331 (28%), Positives = 142/331 (42%), Gaps = 41/331 (12%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--I 124
+V+ G G Q A +VTV ++DVNDN P F PY + E P G F
Sbjct: 464 VVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDS 523
Query: 125 GPSLTIPLTVP----------RGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFA 173
G + + + G + R DR+ T Y++ VS D G
Sbjct: 524 GENGRLSFNISAGDDGGHFSINGSGLVTTARELDRETIAT------YTLTVSAYDHG--- 574
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQ--LVIMAS-GKRIHKEILFPEPIHAIDQDLGVGAT 230
+ S HK V L VLD + + L I + + + I A+D D G
Sbjct: 575 VSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQ 634
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L Y + G+ R F+L+S G L + LD E +++ L + + +P T
Sbjct: 635 LTYSMSGGDSR--FTLNSATGRLQISPT-GLDRELK---DSYDLIINVTDNGSPPNTNST 688
Query: 291 RVEIELLDLNDNLPEFE------VDFYNISIVENLPN-GFSVLQVMATDKDQGENGEFTY 343
V + +LD+NDN P F+ + Y I++ E +++ + ATD D NG+ Y
Sbjct: 689 TVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAY 748
Query: 344 QLD-DPKGAFSIDPRSGWLTVRNQTVLDREA 373
L D G F +DP +G L+VR + LDRE+
Sbjct: 749 SLSGDEHGFFRLDPVTGELSVRKE--LDRES 777
Score = 81.8 bits (193), Expect = 1e-13
Identities = 59/172 (34%), Positives = 84/172 (48%), Gaps = 11/172 (6%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I AID D G + ++Y+ + FSL+SVNG L L LD + A +++L
Sbjct: 68 ISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNGELTLGGPLDFEV-----ARSYMLV 122
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A L P ++ V IE+ D++D P F FY I EN P G +V+ V A D D
Sbjct: 123 VIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDV 182
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G N Y++ + G F+ID +G +TV +D E R+ V A E
Sbjct: 183 GINNPILYEIISGNSDGVFTIDSNTGVITVNGS--IDAEKTDVFRITVKASE 232
Score = 79.4 bits (187), Expect = 7e-13
Identities = 109/495 (22%), Positives = 207/495 (41%), Gaps = 36/495 (7%)
Query: 74 LNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIP 131
+N +S L V V +EDVNDN P+F Y + E +P G + A IG + +
Sbjct: 1271 VNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVL 1330
Query: 132 LTVPRGLTIFKDIRAFDR-----DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
++ +T + + A + +++ D +SS V + K
Sbjct: 1331 YSIVENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAI--K 1388
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPE-PIHAIDQDLGVGATLRYELISGNDRKLFS 245
++D + F + R ++ P + A D+D+G A L Y ++SG F+
Sbjct: 1389 LVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSY-VLSGVLYTRFA 1447
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+D G++ + L+ + + ++ L ++A + RV I + D ND++P+
Sbjct: 1448 IDPDTGNITTREPLNRE-----ETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQ 1502
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTV 363
F Y S+ E++ G +V +V TD+D +N Y + + FS++ +G +
Sbjct: 1503 FTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETTG--II 1560
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKTTY--V 420
+ LDRE ++S + + AK+ + +S + + N PL K+ Y
Sbjct: 1561 STTSTLDREQNASYTLIITAKDHGIPAL----ESNTSVMITIEDVNDNKPLFSKSVYNVT 1616
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTL-LDANDNNPVF-VPSNLYEFSMKSNAKV-GT 477
+ V KT+ ++ N + T + A D + VF + +N ++K+ T
Sbjct: 1617 LRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIKAKLDYEKT 1676
Query: 478 VIGKVKAVDPDLGQ---NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL 534
+ + DLG G ++ S++ +P P + + E+ + G H +
Sbjct: 1677 SLYNLTVSAQDLGTPPLTGACFVEI-HVSDVDDNAPVFHKPRY-SAELYEN-VTRGHHVI 1733
Query: 535 FVEASDQPANPSERR 549
V A+D A S +R
Sbjct: 1734 TVNATDIDAEASHKR 1748
Score = 75.4 bits (177), Expect = 1e-11
Identities = 48/137 (35%), Positives = 70/137 (51%), Gaps = 8/137 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA---EHNLQAN-TFV 273
I+A D D + Y L SG++ F LD V G L + KELD ++ N Q + F+
Sbjct: 733 INATDPDADANGKVAYSL-SGDEHGFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFL 791
Query: 274 LQVQASQLNNPL---KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
L + A+ P+ K+A RV I + D NDN P+F+ Y + E G +V+QV A
Sbjct: 792 LDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSA 851
Query: 331 TDKDQGENGEFTYQLDD 347
TD+D G+ Y + D
Sbjct: 852 TDQDLEYKGKVIYNITD 868
Score = 72.5 bits (170), Expect = 8e-11
Identities = 53/178 (29%), Positives = 89/178 (50%), Gaps = 11/178 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D+D +G T+ Y + +G+ LF++D+V G + ELD + + L VQ
Sbjct: 1214 ITALDKD--IGDTISYSIANGDPYGLFTIDNVTGEIRTVAELDRE-----NVTQYELFVQ 1266
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A N L + +V +++ D+NDN P F + Y I E P G S+LQV A D D G+
Sbjct: 1267 AKDSVN-LVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGD 1325
Query: 338 NGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
N Y + ++ +++ +G +++ + LDRE + A ++ PS T
Sbjct: 1326 NAAVLYSIVENVTDYVTVNAITGVISL-GSSQLDREVEEYFNFTIRATDSGVPSKSST 1382
Score = 68.9 bits (161), Expect = 1e-09
Identities = 55/167 (32%), Positives = 77/167 (46%), Gaps = 17/167 (10%)
Query: 749 RDVYRMTVIAE--FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
+D Y TV E FN G ++ G + ++D NDN PVF Y I EN+++GT I
Sbjct: 6 QDNYEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTI 65
Query: 807 KMDNIIKATDADEGTNALFMY---TLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
I A DAD GTN+ Y F ++ G + +G LD E Y L
Sbjct: 66 LK---ISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNGELT-LGGPLDFEVARSYML 121
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEF------NQIEENSKV 902
++A D G L S +II + D +D P F +IEEN+ +
Sbjct: 122 VVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPI 168
Score = 68.9 bits (161), Expect = 1e-09
Identities = 68/253 (26%), Positives = 101/253 (39%), Gaps = 14/253 (5%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
SA + V++ + D NDN P F Y + E G I S T +G
Sbjct: 808 SATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNV-------IQVSATDQDLEYKG 860
Query: 138 LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
I+ + K HY+ N + S + ++ V D + D F
Sbjct: 861 KVIYNITDGDENRKCEVEKLVRHYNWHKKNCVLCKESKCSVERTYVVIYVDDVNDNDPVF 920
Query: 198 QLVIMASGKRIHKEILFPE-PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
A+ + P +HA D+D G + Y+L +GN FS+++V G + +
Sbjct: 921 NQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVA 980
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
+D +A H TFVL VQA P + A V I + D NDN P+F Y I
Sbjct: 981 GVIDREAVH-----TFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEI 1035
Query: 316 VENLPNGFSVLQV 328
EN P G ++ V
Sbjct: 1036 AENSPVGSTITMV 1048
Score = 66.1 bits (154), Expect = 7e-09
Identities = 46/169 (27%), Positives = 82/169 (48%), Gaps = 9/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G+ A + Y +G + K F + G + ++ LD + + N ++L V
Sbjct: 1111 VTATDRDEGINAIIFYSS-NGAEAK-FYVSRSTGDIIVDSPLDREFK-----NVYILNVT 1163
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ + + +V I + D+ D+ P F + + EN G +V ++ A DKD G+
Sbjct: 1164 AANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGD 1223
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
++ DP G F+ID +G +R LDRE + + V AK++
Sbjct: 1224 TISYSIANGDPYGLFTIDNVTG--EIRTVAELDRENVTQYELFVQAKDS 1270
Score = 60.5 bits (140), Expect = 3e-07
Identities = 66/239 (27%), Positives = 101/239 (42%), Gaps = 33/239 (13%)
Query: 930 DVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DVD P+F P EN+ G +I +NA D+D+ + + VY +
Sbjct: 1705 DVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEAS-------HKRVYYRIESGN 1757
Query: 983 ADALEVKRYFVINERHGHVIVARSLPP-------ESEFRLNISALDGGNLNDNISVR--- 1032
D++ F+I E+ G VI P + + L ++A+ NL + S+
Sbjct: 1758 TDSM-----FLIGEQSG-VITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAV 1811
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEE--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
+ V DVND+ P F Y +V E T + V A D D G++ + + I + +
Sbjct: 1812 ITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNEN 1871
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F++ TGVL+ LDRE Y L V+A D G D+NDN P
Sbjct: 1872 GVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKG-EPALSSSVTVNITVLDMNDNLP 1929
Score = 59.7 bits (138), Expect = 6e-07
Identities = 49/158 (31%), Positives = 77/158 (48%), Gaps = 8/158 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA-SQLNNPLKTAQAR 291
Y + SGN +F + +G + L A + LQV A S++N + +
Sbjct: 1751 YRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRETHAR-YELQVAAISRVNLTEQKSLVP 1809
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLP--NGFSVLQVMATDKDQGENGE--FTYQLDD 347
I +LD+NDN P F+ + Y S++E+ ++L V A D D+GE+GE FT +
Sbjct: 1810 AVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGN 1869
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G F +D ++G LT LDRE S + V A++
Sbjct: 1870 ENGVFQMDNKTGVLT--RTRPLDREDTSFYSLVVMAED 1905
Score = 55.2 bits (127), Expect = 1e-05
Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 19/196 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + + ++SGN+ +F +D+ G L + LD + + + L V
Sbjct: 1848 VKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDRE-----DTSFYSLVVM 1902
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF--------YNISIVENLPNGFSVLQVM 329
A P ++ V I +LD+NDNLP + S+ ENL G V V
Sbjct: 1903 AEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVA 1962
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
A D D + + + F ++ SG L R + LDRE SS+ +Y K +N
Sbjct: 1963 AQDLDTKNLIYYYITNTEEQKYFILNETSGEL--RTRITLDRE-DSSVHY-LYVKASNDK 2018
Query: 390 VVGTFADSQRIAKWRR 405
+ Q +A+ RR
Sbjct: 2019 L--NITTLQPLARKRR 2032
Score = 44.4 bits (100), Expect = 0.024
Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
L TA+ + I L+ ND P FE Y +++ E+ G + +V ATD+D+G N Y
Sbjct: 1070 LLTAREKRPITLI--NDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS 1127
Query: 345 LDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ + F + +G + V + LDRE
Sbjct: 1128 SNGAEAKFYVSRSTGDIIV--DSPLDRE 1153
Score = 43.2 bits (97), Expect = 0.056
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FS 353
D NDN P F Y I EN G ++L++ A D D G N + Y+ + FS
Sbjct: 38 DYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATATQTPFFS 97
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++ +G LT+ LD E S + V A++
Sbjct: 98 LNSVNGELTLGGP--LDFEVARSYMLVVIAED 127
Score = 41.1 bits (92), Expect = 0.23
Identities = 50/222 (22%), Positives = 89/222 (40%), Gaps = 10/222 (4%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV-GTVIGKVKAVDPDLGQNGMVLYDL 499
S V +T+LD NDN P F + ++ + I VKA D D G++G +++ +
Sbjct: 1806 SLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTI 1865
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD--QPANPSERRYSLAVV 555
+ F+++ TG ++ E ++L V A D +PA S ++ V+
Sbjct: 1866 VSGNE---NGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVL 1922
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+ D+ F V N+ G VG + D +N + Y + E
Sbjct: 1923 DMNDNLPILQTPMDVL-IPERRTTFSVKENLDAGVPVGVVAAQDLDTKNLIYY-YITNTE 1980
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS 657
E F + E SG + L R + ++ A + N++
Sbjct: 1981 EQKYFILNETSGELRTRITLDREDSSVHYLYVKASNDKLNIT 2022
Score = 41.1 bits (92), Expect = 0.23
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 14/115 (12%)
Query: 439 LMSFVNVEVTLLDANDNNP-------VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
L S V V +T+LD NDN P V +P FS+K N G +G V A DL
Sbjct: 1911 LSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAA--QDLDT 1968
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPAN 544
++ Y + T F +N +G + + E H L+V+AS+ N
Sbjct: 1969 KNLIYYYITNTEE---QKYFILNETSGELRTRITLDREDSSVHYLYVKASNDKLN 2020
>UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1888
Score = 195 bits (475), Expect = 9e-48
Identities = 193/733 (26%), Positives = 318/733 (43%), Gaps = 50/733 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+LM V++ + D ND++PVF + YE ++K + +VG + V A D D G N +
Sbjct: 1129 ERLMGVCQVDIRIGDKNDHDPVF-QNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLT 1187
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLA 553
Y +Q ++ F I+ TGTV+ S + E + + V + + AN +
Sbjct: 1188 YSIQPQNDY-----FAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKT 1242
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V + +T GN P P F Y V ++ IG+S+ Q+ + + + Y ++ G
Sbjct: 1243 VTLVRITVLDLGNDP--PVFSQGVYVVTVREDIAIGSSLIQLSASTKTNKL-IYYSIVPG 1299
Query: 614 Y---EEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
P F + G++ L + A + +S N + + DV
Sbjct: 1300 NVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIRAETTDPPMSAFANLKIFLEDV 1359
Query: 670 NDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND + + HV EN+ G+++ Q+ + S G V + +D +D
Sbjct: 1360 NDNPPEFVMPRYQG---HVSENAPIGSSVLQVSARDRDS---GENGRVTYSFVQDKD-SD 1412
Query: 729 DIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ E+ G + T++ DRE + Y + + A N G V I I DENDNPP+F
Sbjct: 1413 KFGLDENTGLVTTREEFDREAQGRYTLALKARDN-GSPQKTTDTIVEIIITDENDNPPIF 1471
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVV 846
E Y ++E++ G E+ + A D D G NA Y + G F+V+ G +
Sbjct: 1472 EEKVYNISVLESAASGMELLK---VSAVDRDFGVNARVSYYISEGNINGAFEVNREFGTI 1528
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ G +LDRE YKL+L A+D G S EA + + + D NDN P+F E S R++
Sbjct: 1529 RLAG-TLDRENVDHYKLTLTAKD-GKYSGEATVNVYVLDINDNNPKF----EKSHYRVN- 1581
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF--LIPENIPIGTTIIKLNALDLDSGLNG 964
N AG +++++ + D+ + G + + + I + D G
Sbjct: 1582 -VSENRPAGTLVVKLRASDP---DLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIG 1637
Query: 965 QIRYEFNSEVYI-PPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALD 1021
+ + + S + D +V V+ + G + R L E S + + ++A D
Sbjct: 1638 HVMENLKAGASVMTMSAVDIDDPDVGNNAVMTDT-GVIRTRRMLDREKRSSYDIVVAATD 1696
Query: 1022 GGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
GG+ + V+V V D ND P F K + + E+ + V ATD D G NA
Sbjct: 1697 GGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAK 1756
Query: 1080 LTYFIQ-PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
L Y ++ + + PF I TG + + LD ET+ Y L V RD+G
Sbjct: 1757 LKYSLEYEAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLT 1816
Query: 1139 XXXXDVNDNSPKF 1151
D ND +P+F
Sbjct: 1817 VEVLDANDRAPRF 1829
Score = 139 bits (336), Expect = 6e-31
Identities = 194/763 (25%), Positives = 315/763 (41%), Gaps = 73/763 (9%)
Query: 422 PDKVGTK-TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
P+ +G T NI D +S V V + D N++ PVF Y + + T +
Sbjct: 1000 PELIGPYYTMNISASDGLHVSQAMVIVAIQDVNNHKPVFTDCASYHPVVMEDDPPNTFVM 1059
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD 540
+V A D D G NG V+Y +++ S F I+ TG V+ +S E + +
Sbjct: 1060 QVHADDQDTGANGEVIYSIEKPPGAL--SYFAIDDKTGIVTTLQSFDREEKPVYQIRIIG 1117
Query: 541 QPANPSERRYS---LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV 597
+ R + + V +++ G K N D P F YE + + +G SV +
Sbjct: 1118 RDGGLGSSRGAERLMGVCQVDIRIGDK-NDHD-PVFQNKQYEATIKEDFEVGRSVLHVSA 1175
Query: 598 NDAFEQNDVSYDLLHGYE-EGVPFAVEERSGVITVVDDL------SRYNRPMYDFEAVAL 650
DA ++ L + + + FA++ +G +T L + + F VA
Sbjct: 1176 TDADAGSNAK--LTYSIQPQNDYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVA- 1232
Query: 651 QENANLS--IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIF---HTN 704
+N N+S VT + V+D+ ++ V +G + + V+E+ A G+++ Q+ TN
Sbjct: 1233 NDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVY---VVTVREDIAIGSSLIQLSASTKTN 1289
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
Y GNV ++ I I++ G ++ LD ++ + +T+ AE
Sbjct: 1290 KLIYYSIVPGNVP---SSNNPPRFQIRISK-GIVWNSHRLDHKETSNFSLTIRAETTDPP 1345
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+S + I++ED NDNPP F Y+G + EN+ IG+ + + A D D G N
Sbjct: 1346 MSAFA--NLKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQ---VSARDRDSGENGR 1400
Query: 825 FMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--I 881
Y+ + + F +DENTG+V + DRE + Y L+L ARD G + I I
Sbjct: 1401 VTYSFVQDKDSDKFGLDENTGLVT-TREEFDREAQGRYTLALKARDNGSPQKTTDTIVEI 1459
Query: 882 MIGDENDNKPEFNQIEENSKVRIHRET---KLNGTAGFTIIEVKPKNKFALDVDQLGPLF 938
+I DENDN P F + N V + L +A V + + + + F
Sbjct: 1460 IITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAF 1519
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK-RYFVINER 997
+ N G TI LD ++ + ++ Y + ++ L++ +
Sbjct: 1520 EV--NREFG-TIRLAGTLDRENVDHYKLTLTAKDGKYSGEATVNVYVLDINDNNPKFEKS 1576
Query: 998 HGHVIVARSLPPES-EFRLNISALD---GGNLNDNISVR--VFVKDVNDHFPVFKKTWYN 1051
H V V+ + P + +L S D G +IS + + V DVND+ P F Y
Sbjct: 1577 HYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYI 1636
Query: 1052 FNVEE---AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+V E A + + VD D D G NA +T TGV+ L
Sbjct: 1637 GHVMENLKAGASVMTMSAVDIDDPDVGNNAVMTD----------------TGVIRTRRML 1680
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
DRE Y + V A D G D ND P+F
Sbjct: 1681 DREKRSSYDIVVAATDGG-DPPQEGKVKVKVIVDDANDQHPQF 1722
Score = 121 bits (291), Expect = 2e-25
Identities = 126/494 (25%), Positives = 222/494 (44%), Gaps = 45/494 (9%)
Query: 418 TYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT 477
T+ F + +N +Y + + S +V++ L D NDN P F + Y ++ +A VGT
Sbjct: 798 THRFTAEARNTRDNTDYAN--IDSEADVKIVLRDLNDNPPEFFELS-YRDTLPESAPVGT 854
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALF 535
+ V A D D G NG Y ++ + F ++P TG ++ E H+
Sbjct: 855 TVLSVTARDLDSGVNGQFHYFVE-------SQFFSVDPYTGWITTKRPLDFETNPTHSFL 907
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
V A D NP+ R A V +E+T + P F + Y +V + G V +
Sbjct: 908 VVAQDS-GNPA--RNGTARVIVELT----NVNDNAPRFSQSLYNVFVAEDAGSDQLVATV 960
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
+ D + + V+Y + G + F + ++GVI +V + Y ++ + +
Sbjct: 961 QATDK-DNDPVTYSIASG-DNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLH 1018
Query: 656 LSIVTNATVHVVDVNDERGVLLK-GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+S V + DVN+ + V ++ P++ ++++ + Q+ H + N G
Sbjct: 1019 VS-QAMVIVAIQDVNNHKPVFTDCASYHPVV--MEDDPPNTFVMQV-HADDQDTGAN--G 1072
Query: 715 NVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGA---- 768
V + I AI + G + T + DRE++ VY++ +I + G GA
Sbjct: 1073 EVIYSIEKPPGALSYFAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLM 1132
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
G+ QV I I D+ND+ PVF++ YE I E+ ++G + + ATDAD G+NA Y+
Sbjct: 1133 GVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLH---VSATDADAGSNAKLTYS 1189
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREK-----KIMYKLSLVARDTGGLSSEAELIIMI 883
+ + + F +D TG V L K + ++VA D G +S + ++ I
Sbjct: 1190 IQPQ-NDYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRI 1248
Query: 884 G--DENDNKPEFNQ 895
D ++ P F+Q
Sbjct: 1249 TVLDLGNDPPVFSQ 1262
Score = 108 bits (259), Expect = 1e-21
Identities = 126/541 (23%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y + D F LD G + +E D +A+ + L ++
Sbjct: 1388 VSARDRDSGENGRVTYSFVQDKDSDKFGLDENTGLVTTREEFDREAQ-----GRYTLALK 1442
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P KT VEI + D NDN P FE YNIS++E+ +G +L+V A D+D G
Sbjct: 1443 ARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGV 1502
Query: 338 NGEFTYQLDDP--KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE---TNPSVVG 392
N +Y + + GAF ++ G T+R LDRE ++ + AK+ + + V
Sbjct: 1503 NARVSYYISEGNINGAFEVNREFG--TIRLAGTLDRENVDHYKLTLTAKDGKYSGEATVN 1560
Query: 393 TFA--DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
+ + K+ + N + K+ ++ + L + ++
Sbjct: 1561 VYVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIV 1620
Query: 451 -DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV---DPDLGQNGMVLYDLQRTSNLT 506
D NDN P F P Y + N K G + + AV DPD+G N ++
Sbjct: 1621 GDVNDNKPRF-PDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVM----------- 1668
Query: 507 ITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+TG + E R + + V A+D P E + + V+ +
Sbjct: 1669 --------TDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDA----- 1715
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAV 622
P F + + + +G++V + D E + Y L + +E PF +
Sbjct: 1716 --NDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEERPFRI 1773
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVNDERGVLLKGA 680
+E +G I + L + Y + LS A TV V+D ND +
Sbjct: 1774 DETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLS 1833
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA-NQQDVTDDIAIAEDGTIF 739
+S ++ ++ G + ++ T+ S NG G +F I+ N++++ + + EDG +
Sbjct: 1834 YSAVV--REDVDIGERLLRLEVTDPDSDSQNG-GPFKFGISGNEKNLFE---LTEDGVLK 1887
Query: 740 T 740
T
Sbjct: 1888 T 1888
Score = 107 bits (257), Expect = 2e-21
Identities = 121/466 (25%), Positives = 207/466 (44%), Gaps = 46/466 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD N+N+P+F S+ Y ++ + +GT + +V A D D G N V Y ++SN
Sbjct: 1 VIVRVLDGNNNDPIFQQSS-YWVALPEGSPIGTELLRVTAEDLDSGSNADVKY---QSSN 56
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F ++ TGT+++ +++ V A DQ PS +V T+ V+ +
Sbjct: 57 ----DIFAVDETTGTITLQYQASRNKKYSFTVTAFDQ-GKPSRS----SVATVYVSIHSF 107
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR--VNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P F + YE + N + + ++ N ++ Y L+ G + F V
Sbjct: 108 SDSP--PVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQS-QFNV 164
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQE--NANL-SIVTNATV--HVVDVNDERGVLL 677
+ +G +++ L Y A+Q+ N+ + ATV V D+ND
Sbjct: 165 DRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDIND-NAPRF 223
Query: 678 KGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
P++ + + AG + ++ + S V++ + N I + G
Sbjct: 224 AIPREPLVTSIHQFRPAGTTVTKVTAYDQDS---GSHALVKYGLENADSFPFTIT-PQTG 279
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT--IYIEDENDNPPVFEHATYEG 794
I T L +RD Y V A S ++VT I + D NDNPP+F Y+
Sbjct: 280 VIKTTAELRHFERDFYAFVVTA-----TDSTPPFHKVTANIQLGDVNDNPPLFAQPVYKV 334
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDENTGVVKFIG 850
F+ EN + G I A D D+G NA Y++ +F + TGV+ +
Sbjct: 335 FVRENLQGGHVIGQ---FAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTAL- 390
Query: 851 DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
+LDRE + L++ A+DTG +S A+++I++ D ND+ P F+
Sbjct: 391 STLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFS 436
Score = 106 bits (255), Expect = 4e-21
Identities = 191/815 (23%), Positives = 313/815 (38%), Gaps = 94/815 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G ++ V + I D ND+ P+F + Y T+ E G L
Sbjct: 1127 GAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKL 1186
Query: 133 T-----------VPRGL-TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKP 180
T + R T+ + K +S V V ND+G+ S K
Sbjct: 1187 TYSIQPQNDYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNV----SRKT 1242
Query: 181 VLLLR-KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
V L+R VLD F + + ++I + + + Y ++ GN
Sbjct: 1243 VTLVRITVLDLGNDPPVFSQGVYVV--TVREDIAIGSSLIQLSASTKTNKLIYYSIVPGN 1300
Query: 240 -----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ F + G ++ LD + + + F L ++A + P+ +A A ++I
Sbjct: 1301 VPSSNNPPRFQIRISKGIVWNSHRLD-----HKETSNFSLTIRAETTDPPM-SAFANLKI 1354
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAF 352
L D+NDN PEF + Y + EN P G SVLQV A D+D GENG TY D F
Sbjct: 1355 FLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSDKF 1414
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNA 412
+D +G +T R + DREA + + A++ N S T + I + N
Sbjct: 1415 GLDENTGLVTTREE--FDREAQGRYTLALKARD-NGSPQKT---TDTIVEIIITDENDNP 1468
Query: 413 PLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLD----ANDNNPVFVPSNLYEFS 468
P +F +KV NI + ++V+ +D N ++ +
Sbjct: 1469 P------IFEEKV----YNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGA 1518
Query: 469 MKSNAKVGTV--IGKVKAVDPDLGQNGMVLYDLQRTSNLTI-TSPFKINPNTG------- 518
+ N + GT+ G + + D + + D + + T+ IN N
Sbjct: 1519 FEVNREFGTIRLAGTLDRENVDHYKLTLTAKDGKYSGEATVNVYVLDINDNNPKFEKSHY 1578
Query: 519 TVSVAESPILEGRHALFVEASDQPANPSER-RYSLAVVTIEVTRGTKGNKPDIPDFMGAP 577
V+V+E+ G + + ASD S + Y ++ + + NKP PD P
Sbjct: 1579 RVNVSENR-PAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPD---EP 1634
Query: 578 YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSR 637
Y V N+ G SV + D + DV + AV +GVI L R
Sbjct: 1635 YIGHVMENLKAGASVMTMSAVD-IDDPDVGNN-----------AVMTDTGVIRTRRMLDR 1682
Query: 638 YNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGA 695
R YD VA + + V V+ D ND+ K +F K S A
Sbjct: 1683 EKRSSYDI-VVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKR-----VFAAK-ISESA 1735
Query: 696 AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFTQKPLDREKRDVY 752
A+G T ++ G N + + + + ++ D G I LD E + Y
Sbjct: 1736 ALGSTVATVSATDRDEGV-NAKLKYSLEYEAKEERPFRIDETTGEIILALTLDYETKRNY 1794
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
R+ V + +S + +T+ + D ND P FE +Y + E+ IG + + +
Sbjct: 1795 RLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERL-LRLEV 1853
Query: 813 KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
D+D F + + G K +F++ E+ GV+K
Sbjct: 1854 TDPDSDSQNGGPFKFGISGNEKNLFELTED-GVLK 1887
Score = 99.1 bits (236), Expect = 8e-19
Identities = 149/663 (22%), Positives = 280/663 (42%), Gaps = 85/663 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+LD ++ PVF +Y +++ + +G+ + ++ A N ++ Y + +
Sbjct: 1246 VRITVLDLGNDPPVF-SQGVYVVTVREDIAIGSSLIQLSA---STKTNKLIYYSIVPGNV 1301
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ +P + V S L+ + + + A ++ S A +++
Sbjct: 1302 PSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIR-AETTDPPMS-AFANLKIFLEDV 1359
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P+F+ Y+ V N IG+SV Q+ R D+ E V+Y + ++ F +
Sbjct: 1360 NDNP--PEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQD-KDSDKFGL 1416
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGA 680
+E +G++T ++ R + Y A+ ++N + T+ V ++ D ND + +
Sbjct: 1417 DENTGLVTTREEFDREAQGRYTL-ALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKV 1475
Query: 681 HSPIIFHVKENSAG----AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
++ + + +A+ + F N Y GN+ + E G
Sbjct: 1476 YNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNR---------EFG 1526
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
TI LDRE D Y++T+ A+ G SG V +Y+ D NDN P FE + Y +
Sbjct: 1527 TIRLAGTLDRENVDHYKLTLTAK--DGKYSGEAT--VNVYVLDINDNNPKFEKSHYRVNV 1582
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN GT + ++A+D D G + GK ++D+ G++ +GD D +
Sbjct: 1583 SENRPAGTLVVK---LRASDPDLGES----------GKFLYDIS-GQGLM-IVGDVNDNK 1627
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ--IEENSKVRIHRETKLNGTA 914
+ + + L + A ++ M + D+ N + + +R R +
Sbjct: 1628 PRFPDE-PYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRS 1686
Query: 915 GFTII-----------EVKPKNKFALD-VDQLGPLFL-------IPENIPIGTTIIKLNA 955
+ I+ E K K K +D + P F I E+ +G+T+ ++A
Sbjct: 1687 SYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSA 1746
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--F 1013
D D G+N +++Y E + +R F I+E G +I+A +L E++ +
Sbjct: 1747 TDRDEGVNAKLKYSLEYEA------------KEERPFRIDETTGEIILALTLDYETKRNY 1794
Query: 1014 RLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
RL + D G + +D S+ V V D ND P F+ Y+ V E L +++ T
Sbjct: 1795 RLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVT 1854
Query: 1071 DAD 1073
D D
Sbjct: 1855 DPD 1857
Score = 90.2 bits (214), Expect = 4e-16
Identities = 117/470 (24%), Positives = 192/470 (40%), Gaps = 45/470 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+L + V +T+ D NDN P F +P S+ GT + KV A D D G + +V
Sbjct: 202 ELPAEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVK 261
Query: 497 YDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y L+ + PF I P TG + + AE E FV + P + V
Sbjct: 262 YGLENADSF----PFTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHK------V 311
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG 613
T + G + P P F Y+ +V N+ G +GQ D + + V+Y +++
Sbjct: 312 TANIQLGDVNDNP--PLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIIN- 368
Query: 614 YEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
+E+ F++ +GV+T + L R + + A +S + + V DV
Sbjct: 369 FEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDV 428
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI--ANQQDVT 727
ND G+ FHV+ ++F G G VR+ I N+Q
Sbjct: 429 NDHAPRFSSGS-----FHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYF 483
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I DG++F LD + + + + + G + + I+I + PP F
Sbjct: 484 SINHI--DGSLF----LDEKLTTLEPIDIKVTRDMGQPERSSTADIRIFIHVQA-GPPQF 536
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVV 846
+ + G + EN G + I A D MY++ G F + G +
Sbjct: 537 LSSPFVGNVTENEPKGAFVVH---ISAASLDP-----VMYSIVSGNEAGNFRLHPGVGWL 588
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
+ LD EK+ YK+ ++A D S+ E+I+ + + NDNKP+F I
Sbjct: 589 TTVRP-LDNEKQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNI 637
Score = 89.4 bits (212), Expect = 7e-16
Identities = 115/446 (25%), Positives = 186/446 (41%), Gaps = 56/446 (12%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
P GTT+ K+ A D DSG + ++Y + P F I + G +
Sbjct: 239 PAGTTVTKVTAYDQDSGSHALVKYGLENADSFP--------------FTITPQTGVIKTT 284
Query: 1005 RSLPP-ESEF-RLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E +F ++A D ++ + + DVND+ P+F + Y V E
Sbjct: 285 AELRHFERDFYAFVVTATDSTPPFHKVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGH 344
Query: 1063 VLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
V+G+ A D D G NA +TY I + S +D F I P TGVL+ LDRE ++ILT
Sbjct: 345 VIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILT 404
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
+ A+D G DVND++P+F + +E P + F++ +
Sbjct: 405 IQAKDTG-VPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVE--IPLNTPPDSRVFQARALD 461
Query: 1180 P--VYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILYSLPQRKNQQNLGLPSLSSTA 1236
P + + + G N D + L K +++G P SSTA
Sbjct: 462 PDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKVTRDMGQPERSSTA 521
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILN 1296
+ + + V+ + P F+S + + EN +V ++ + Y I++
Sbjct: 522 DIRIFI-----HVQ-AGPPQFLSSPFVGNVTENEPKGAFVVHISAA---SLDPVMYSIVS 572
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVL 1356
N+ F + P G L VR D E + Y++IV +A D+
Sbjct: 573 GNEAG---NFRLHPGVGWLTTVRPLDNEKQSRYKIIV-----------------MAMDLK 612
Query: 1357 EGMTKYDVKVVVRIKDVNDNSPKFTN 1382
++K V+V+V + +VNDN PKF N
Sbjct: 613 NRVSK--VEVIVNVLNVNDNKPKFVN 636
Score = 84.6 bits (200), Expect = 2e-14
Identities = 104/479 (21%), Positives = 190/479 (39%), Gaps = 57/479 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE PIGT ++++ A DLDSG N ++Y+ ++++ F ++E G
Sbjct: 24 LPEGSPIGTELLRVTAEDLDSGSNADVKYQSSNDI-----------------FAVDETTG 66
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEA 1057
+ + ++ ++A D G + + V+V +D PVF+K+ Y + E
Sbjct: 67 TITLQYQASRNKKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPEN 126
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+R + +V+A G L Y++ D F + LTG LS+ LD E Y
Sbjct: 127 FALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYR 186
Query: 1118 LTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
L + A D+NDN+P+F E L S H F
Sbjct: 187 LRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPL--------VTSIHQFR 238
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDF---IGNGNGLILYSLPQRKNQQN---LG 1228
++++ V N F I G+I + R +++
Sbjct: 239 PAGTTVTKVTAYDQDSGSHALVKYGLENADSFPFTITPQTGVIKTTAELRHFERDFYAFV 298
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA--PVELVSLNLTEHYE 1286
+ + ST A++ + P+F Y++ + EN+ + + +
Sbjct: 299 VTATDSTPPFHKVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGA 358
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N ++ Y I+N D+ F I P G L + + DRE + + ++A+ +P
Sbjct: 359 NARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAK----DTGVPR 414
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
M G+ ++V+ + DVND++P+F++G+ IP P +V Q +
Sbjct: 415 M---------SGL----AQIVIIVDDVNDHAPRFSSGS--FHVEIPLNTPPDSRVFQAR 458
Score = 83.8 bits (198), Expect = 3e-14
Identities = 127/524 (24%), Positives = 220/524 (41%), Gaps = 68/524 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V L + NDN P F S LY + +A ++ V+A D D N V Y + N
Sbjct: 924 VIVELTNVNDNAPRFSQS-LYNVFVAEDAGSDQLVATVQATDKD---NDPVTYSIASGDN 979
Query: 505 LTITSPFKINPNTGTVSVAES--PILEGRH-ALFVEASDQPANPSERRYSLAVVTIEVTR 561
T+ F IN TG + + + P L G + + + ASD S A+V + + +
Sbjct: 980 ---TTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDG------LHVSQAMVIVAI-Q 1029
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-- 619
+KP D A Y V + T V Q+ +D + + ++++ E+
Sbjct: 1030 DVNNHKPVFTDC--ASYHPVVMEDDPPNTFVMQVHADD--QDTGANGEVIYSIEKPPGAL 1085
Query: 620 --FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
FA+++++G++T + R +P+Y + S + V V+ G
Sbjct: 1086 SYFAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGD-- 1143
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT----GNVRFLIANQQDVTDDIAIA 733
K H P+ F K+ A I + F S ++ + T G+ L + Q D AI
Sbjct: 1144 KNDHDPV-FQNKQYEA--TIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQNDYFAID 1200
Query: 734 E-DGTIFTQKPLDREKRDVYRMTVIAEFN-----KGVISGAGIYQVTIYIEDENDNPPVF 787
GT+ ++ L E + + + + FN G +S + V I + D ++PPVF
Sbjct: 1201 RATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGNDPPVF 1260
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF------GEGKEMFDVDE 841
Y + E+ IG+ ++I+ + A TN L Y++ F +
Sbjct: 1261 SQGVYVVTVREDIAIGS-----SLIQLS-ASTKTNKLIYYSIVPGNVPSSNNPPRFQIRI 1314
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEF------N 894
+ G+V + LD ++ + L++ A T +S+ A L I + D NDN PEF
Sbjct: 1315 SKGIV-WNSHRLDHKETSNFSLTIRAETTDPPMSAFANLKIFLEDVNDNPPEFVMPRYQG 1373
Query: 895 QIEENSKVRIH--------RETKLNGTAGFTIIEVKPKNKFALD 930
+ EN+ + R++ NG ++ ++ K +KF LD
Sbjct: 1374 HVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSDKFGLD 1417
Score = 82.2 bits (194), Expect = 1e-13
Identities = 112/488 (22%), Positives = 204/488 (41%), Gaps = 45/488 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + L D NDN P+F +Y+ ++ N + G VIG+ A DPD G N V Y +
Sbjct: 311 VTANIQLGDVNDNPPLFAQP-VYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINF 369
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ + F I+P TG ++ + E RH L ++A D R LA + I V
Sbjct: 370 EDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGV---PRMSGLAQIVIIVD 426
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV 618
P F + + N + V Q R D ++ V Y ++ G ++G
Sbjct: 427 ----DVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGY 482
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F++ G + + + L+ P+ D + S + + + V L
Sbjct: 483 -FSINHIDGSLFLDEKLTTLE-PI-DIKVTRDMGQPERSSTADIRIFI-HVQAGPPQFLS 538
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
SP + +V EN A + H + +S+ V + I + + + G +
Sbjct: 539 ---SPFVGNVTENEPKGAF--VVHISAASL-----DPVMYSIVSGNEAGNFRLHPGVGWL 588
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF---EHATYEGF 795
T +PLD EK+ Y++ V+A K +S +V + + + NDN P F + EG
Sbjct: 589 TTVRPLDNEKQSRYKIIVMAMDLKNRVSKV---EVIVNVLNVNDNKPKFVNIRNGIIEGN 645
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
++++ +G+ + +I A DAD + + Y + E + N GVV D
Sbjct: 646 VLKDVAVGSRVM---VIDAVDADR--SDILSYRIEDEKARRYFSVNNEGVVTSTRVLRDL 700
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
+ ++K+S+ + ++A +++ K + Q ++ + + +E+ GT
Sbjct: 701 DSPYLFKVSVSDNGKPPMVAQAMARVVL-----LKYQPQQDQQRTSI---QESAALGTRV 752
Query: 916 FTIIEVKP 923
FT++ KP
Sbjct: 753 FTLLTAKP 760
Score = 77.4 bits (182), Expect = 3e-12
Identities = 54/165 (32%), Positives = 89/165 (53%), Gaps = 11/165 (6%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT--AQ 289
RY ++S + K F +D +G + + LD + ++ + F + + ++ N ++
Sbjct: 765 RYSIVSPLETK-FRVDPYSGDVRVRSGLDYET---VKTHRFTAEARNTRDNTDYANIDSE 820
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
A V+I L DLNDN PEF Y ++ E+ P G +VL V A D D G NG+F Y ++
Sbjct: 821 ADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQ- 879
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
FS+DP +GW+T + LD E + + V A+++ NP+ GT
Sbjct: 880 -FFSVDPYTGWITTKRP--LDFETNPTHSFLVVAQDSGNPARNGT 921
Score = 76.2 bits (179), Expect = 7e-12
Identities = 103/392 (26%), Positives = 159/392 (40%), Gaps = 47/392 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ P+GTT++ + A DLDSG+NGQ Y S+ + + F N H
Sbjct: 846 LPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQFFSVDPYTGWITTKRPLDFETNPTHS 905
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEA 1057
++VA+ D GN N + RV V+ +VND+ P F ++ YN V E
Sbjct: 906 FLVVAQ---------------DSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAED 950
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ +++ V ATD D N +TY I D F I+ TGV+ + E Y
Sbjct: 951 AGSDQLVATVQATDKD---NDPVTYSIASGDNTTNFVINNKTGVIKLVSNRKPELIGPYY 1007
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
++ +G DVN++ P F + + HP E N VM
Sbjct: 1008 TMNISASDG---LHVSQAMVIVAIQDVNNHKP---VFTDCASY-HPVVMEDDPPN-TFVM 1059
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLI--LYSLPQRKNQ--------QN 1226
+ N + ++ K + F I + G++ L S + + ++
Sbjct: 1060 QVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKTGIVTTLQSFDREEKPVYQIRIIGRD 1119
Query: 1227 LGLPSLSSTAILM-VTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTE 1283
GL S LM V D+ + PVF ++ YE I+E+ V V VS +
Sbjct: 1120 GGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDAD 1179
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
N K+ Y I +ND F ID GT+
Sbjct: 1180 AGSNAKLTYSIQPQND-----YFAIDRATGTV 1206
Score = 74.1 bits (174), Expect = 3e-11
Identities = 98/421 (23%), Positives = 172/421 (40%), Gaps = 39/421 (9%)
Query: 501 RTSNLTITSP----FKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAV 554
R + +I SP F+++P +G V V E H EA + N
Sbjct: 762 RNARYSIVSPLETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYANIDSEA 821
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
V R N P+ F Y + + +GT+V + D + + H +
Sbjct: 822 DVKIVLRDLNDNPPE---FFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQF---HYF 875
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDER 673
E F+V+ +G IT L P + F VA N + V + +VND
Sbjct: 876 VESQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNA 935
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ ++ +F ++ + + + T+ + V + IA+ + T+ +
Sbjct: 936 PRFSQSLYN--VFVAEDAGSDQLVATVQATDKDN------DPVTYSIASGDNTTNFVINN 987
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-EHATY 792
+ G I E Y I+ + +S A V + I+D N++ PVF + A+Y
Sbjct: 988 KTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQA---MVIVAIQDVNNHKPVFTDCASY 1044
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--FDVDENTGVVKFIG 850
+ME+ T + + A D D G N +Y++ + F +D+ TG+V +
Sbjct: 1045 HPVVMEDDPPNTFVMQ---VHADDQDTGANGEVIYSIEKPPGALSYFAIDDKTGIVTTL- 1100
Query: 851 DSLDREKKIMYKLSLVARDTG-GLSSEAELI-------IMIGDENDNKPEFNQIEENSKV 902
S DRE+K +Y++ ++ RD G G S AE + I IGD+ND+ P F + + +
Sbjct: 1101 QSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATI 1160
Query: 903 R 903
+
Sbjct: 1161 K 1161
Score = 73.7 bits (173), Expect = 3e-11
Identities = 95/372 (25%), Positives = 164/372 (44%), Gaps = 41/372 (11%)
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
D N++ V++ ++D+ND+ P F + Y + E+ + V A D D G N
Sbjct: 813 DYANIDSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQF 872
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
YF++ F + P TG ++ LD ET + VVA+D+G
Sbjct: 873 HYFVESQF----FSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSG-NPARNGTARVIVE 927
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF 1200
+VNDN+P+ F + L D S+ ++ +AT ++N P+ ++A
Sbjct: 928 LTNVNDNAPR---FSQSLYNVFVAEDAGSD------QLVATVQATDKDNDPVTYSIAS-G 977
Query: 1201 ANDTDF-IGNGNGLILYSLPQRKNQQNLG---LPSLSSTAILMVTVADVPDEVE--MSDK 1254
N T+F I N G+I L + + +G ++S++ L V+ A V ++ + K
Sbjct: 978 DNTTNFVINNKTGVI--KLVSNRKPELIGPYYTMNISASDGLHVSQAMVIVAIQDVNNHK 1035
Query: 1255 PVF--ISRYYELEIEEN-VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPR 1311
PVF + Y+ + +E++ N V V + + N ++ Y I E F ID +
Sbjct: 1036 PVFTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSI--EKPPGALSYFAIDDK 1093
Query: 1312 NGTLYLVRSPDREVKDTYEV-IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRI 1370
G + ++S DRE K Y++ I+ + S + L G+ + D +RI
Sbjct: 1094 TGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSR--------GAERLMGVCQVD----IRI 1141
Query: 1371 KDVNDNSPKFTN 1382
D ND+ P F N
Sbjct: 1142 GDKNDHDPVFQN 1153
Score = 68.9 bits (161), Expect = 1e-09
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 4/145 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+ G G LRY L+ G+ + F++D + G L L+K LD + + + +Q +
Sbjct: 136 VEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQ-K 194
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI--SIVENLPNGFSVLQVMATDKDQ 335
+ N P A+A V I + D+NDN P F + + SI + P G +V +V A D+D
Sbjct: 195 TWRPNMPELPAEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDS 254
Query: 336 GENGEFTYQLDDPKG-AFSIDPRSG 359
G + Y L++ F+I P++G
Sbjct: 255 GSHALVKYGLENADSFPFTITPQTG 279
Score = 65.3 bits (152), Expect = 1e-08
Identities = 61/190 (32%), Positives = 87/190 (45%), Gaps = 13/190 (6%)
Query: 724 QDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
Q D A+ E GTI Q R K+ Y TV A F++G S + + V + I +D
Sbjct: 53 QSSNDIFAVDETTGTITLQYQASRNKK--YSFTVTA-FDQGKPSRSSVATVYVSIHSFSD 109
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
+PPVF +TYE I EN + I + A G L Y + G+ + F+VD
Sbjct: 110 SPPVFRKSTYEKRIPENFALKRGIVRVEAL-ANGGGAG-GELRYYLVGGDPQSQFNVDRL 167
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVA------RDTGGLSSEAELIIMIGDENDNKPEFNQI 896
TG + + LD EK Y+L + A + L +EA ++I + D NDN P F
Sbjct: 168 TGELS-LKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIP 226
Query: 897 EENSKVRIHR 906
E IH+
Sbjct: 227 REPLVTSIHQ 236
Score = 64.1 bits (149), Expect = 3e-08
Identities = 67/317 (21%), Positives = 135/317 (42%), Gaps = 22/317 (6%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL---T 133
I + V + + D+NDN P F + Y T+ E P G + +
Sbjct: 817 IDSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFV 876
Query: 134 VPRGLTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+ ++ +P + + H +V D G+ A + + ++ L V D
Sbjct: 877 ESQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAP 936
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
+ + + +++ + A D+D + Y + SG++ F +++ G
Sbjct: 937 RFSQSLYNVFVAEDAGSDQLV--ATVQATDKD---NDPVTYSIASGDNTTNFVINNKTGV 991
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFY 311
+ +L + + L + + + AS + L +QA V + + D+N++ P F + Y
Sbjct: 992 I----KLVSNRKPELIGPYYTMNISAS---DGLHVSQAMVIVAIQDVNNHKPVFTDCASY 1044
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA---FSIDPRSGWLTVRNQTV 368
+ ++E+ P V+QV A D+D G NGE Y ++ P GA F+ID ++G +T
Sbjct: 1045 HPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKTGIVTTLQS-- 1102
Query: 369 LDREAHSSLRMKVYAKE 385
DRE ++++ ++
Sbjct: 1103 FDREEKPVYQIRIIGRD 1119
Score = 63.3 bits (147), Expect = 5e-08
Identities = 106/466 (22%), Positives = 190/466 (40%), Gaps = 59/466 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ +G +++ ++A D D+G N ++ Y + YF I+ G
Sbjct: 1160 IKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQ---------------NDYFAIDRATG 1204
Query: 1000 HVIVARSLPPESE--------FRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTW 1049
V SL E++ N+ A D GN++ VR+ V D+ + PVF +
Sbjct: 1205 TVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGV 1264
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP----SDTDLP-FEISPLTGVLSV 1104
Y V E L ++ A+ N + Y I P S + P F+I G++
Sbjct: 1265 YVVTVREDIAIGSSLIQLSASTKT---NKLIYYSIVPGNVPSSNNPPRFQIRISKGIVWN 1321
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
+ LD + + LT+ R DVNDN P+F ++
Sbjct: 1322 SHRLDHKETSNFSLTI--RAETTDPPMSAFANLKIFLEDVNDNPPEF-----VMPRYQGH 1374
Query: 1165 ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
E + SV+ + EN + T + V D+D G L + + ++
Sbjct: 1375 VSENAPIG-SSVLQVSARDRDSGENGRV--TYSFVQDKDSDKFGLDENTGLVTTREEFDR 1431
Query: 1225 QNLGLPSLS-------STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+ G +L+ S T+ ++ E + P+F + Y + + E+ + +EL+
Sbjct: 1432 EAQGRYTLALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELL 1491
Query: 1278 SLNLTEHY--ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ + N ++ YYI N I F ++ GT+ L + DRE D Y++ + A
Sbjct: 1492 KVSAVDRDFGVNARVSYYISEGN---INGAFEVNREFGTIRLAGTLDRENVDHYKLTLTA 1548
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ KYS E +Y + D+ + K++ K R+ +V++N P T
Sbjct: 1549 KDGKYSGEATVNVYVL--DINDNNPKFE-KSHYRV-NVSENRPAGT 1590
Score = 62.1 bits (144), Expect = 1e-07
Identities = 54/174 (31%), Positives = 80/174 (45%), Gaps = 15/174 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A DQD G A ++Y L + D F++ G + EL + + + + V
Sbjct: 247 VTAYDQDSGSHALVKYGLENA-DSFPFTITPQTGVIKTTAEL-----RHFERDFYAFVVT 300
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P A I+L D+NDN P F Y + + ENL G + Q A D D+G
Sbjct: 301 ATDSTPPFHKVTAN--IQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGA 358
Query: 338 NGEFTYQL---DDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N TY + +D + FSI P +G LT + LDRE S + + AK+T
Sbjct: 359 NARVTYSIINFEDSRSDNLFSIHPFTGVLTA--LSTLDREDLSRHILTIQAKDT 410
Score = 60.9 bits (141), Expect = 3e-07
Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 20/211 (9%)
Query: 186 KVLDYDAGDKEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
+VLD + D FQ V + G I E+L + A D D G A ++Y+ S ND
Sbjct: 4 RVLDGNNNDPIFQQSSYWVALPEGSPIGTELL---RVTAEDLDSGSNADVKYQ--SSND- 57
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
+F++D G++ L+ + + +++ F P +++ A V + + +D
Sbjct: 58 -IFAVDETTGTITLQYQASRNKKYSFTVTAF-------DQGKPSRSSVATVYVSIHSFSD 109
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
+ P F Y I EN +++V A G GE Y L DP+ F++D +G
Sbjct: 110 SPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTG 169
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
L+++ ++ A LR++ K P++
Sbjct: 170 ELSLKKPLDYEKVASYRLRIRAVQKTWRPNM 200
Score = 58.4 bits (135), Expect = 1e-06
Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
A D D G A + Y +I+ D + LFS+ G L LD + + +L +
Sbjct: 351 ARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDRE-----DLSRHILTI 405
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
QA P + A++ I + D+ND+ P F +++ I N P V Q A D D G
Sbjct: 406 QAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGG 465
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWL 361
NG Y + + +G FSI+ G L
Sbjct: 466 HNGLVRYSIIQGNKQGYFSINHIDGSL 492
Score = 56.8 bits (131), Expect = 4e-06
Identities = 46/164 (28%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
F +HA DQD G + Y + F++D G + + D + + Q
Sbjct: 1057 FVMQVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKTGIVTTLQSFDREEKPVYQIRII 1116
Query: 273 VLQVQASQLNNPLKT-AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ +V+I + D ND+ P F+ Y +I E+ G SVL V AT
Sbjct: 1117 GRDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSAT 1176
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
D D G N + TY + F+ID +G TV ++ L EA S
Sbjct: 1177 DADAGSNAKLTYSIQPQNDYFAIDRATG--TVTSKMSLLSEAKS 1218
Score = 54.8 bits (126), Expect = 2e-05
Identities = 36/123 (29%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V + + D N+N P+F+ ++Y + E S IGTE+ + A D D G+NA Y
Sbjct: 1 VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLR---VTAEDLDSGSNADVKYQ---S 54
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
++F VDE TG + + R KK + ++ + SS A + + I +D+ P
Sbjct: 55 SNDIFAVDETTGTIT-LQYQASRNKKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPPV 113
Query: 893 FNQ 895
F +
Sbjct: 114 FRK 116
Score = 53.2 bits (122), Expect = 5e-05
Identities = 44/166 (26%), Positives = 76/166 (45%), Gaps = 14/166 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G +RY +I GN + FS++ ++GSLFL+++L +++ + Q + S
Sbjct: 459 ALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKVTRDMGQPERS 518
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
TA R+ + + P+F + ++ EN P G V+ + A D
Sbjct: 519 ------STADIRI---FIHVQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLDP---V 566
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++ + G F + P GWLT LD E S ++ V A +
Sbjct: 567 MYSIVSGNEAGNFRLHPGVGWLTTVRP--LDNEKQSRYKIIVMAMD 610
Score = 47.6 bits (108), Expect = 0.003
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V + +LD N+N P F+ Y +++ E P G +L+V A D D G N + YQ
Sbjct: 1 VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQ--SSNDI 58
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
F++D +G +T++ Q +++ ++ K + SV +
Sbjct: 59 FAVDETTGTITLQYQASRNKKYSFTVTAFDQGKPSRSSVATVY 101
Score = 41.1 bits (92), Expect = 0.23
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V D N++ P+F+++ Y + E L +V A D D G NA++ Y S D
Sbjct: 1 VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKY---QSSND 57
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ F + TG +++ + R KY TV A D G
Sbjct: 58 I-FAVDETTGTITLQYQASR--NKKYSFTVTAFDQG 90
Score = 38.3 bits (85), Expect = 1.6
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 13/177 (7%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y ++SGN+ F L G L + LD N + + + + V A L N + ++ V
Sbjct: 568 YSIVSGNEAGNFRLHPGVGWLTTVRPLD-----NEKQSRYKIIVMAMDLKN--RVSKVEV 620
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSV-LQVMATDK-DQGENGEFTYQLDDPKG 350
+ +L++NDN P+F V+ N I N+ +V +VM D D + +Y+++D K
Sbjct: 621 IVNVLNVNDNKPKF-VNIRNGIIEGNVLKDVAVGSRVMVIDAVDADRSDILSYRIEDEKA 679
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQP 407
+ + + + D ++ ++ V P V A R+ + QP
Sbjct: 680 RRYFSVNNEGVVTSTRVLRDLDSPYLFKVSVSDNGKPPMVAQAMA---RVVLLKYQP 733
Score = 36.7 bits (81), Expect = 4.9
Identities = 51/190 (26%), Positives = 78/190 (41%), Gaps = 21/190 (11%)
Query: 930 DVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DV+ PLF P EN+ G I + A D D G N ++ Y S + S+
Sbjct: 319 DVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTY---SIINFEDSR-- 373
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGG--NLNDNISVRVFVKDV 1038
+D L F I+ G + +L E R L I A D G ++ + + V DV
Sbjct: 374 SDNL-----FSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDV 428
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
NDH P F ++ + + + A D D G N + Y I + F I+ +
Sbjct: 429 NDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHI 488
Query: 1099 TGVLSVNGEL 1108
G L ++ +L
Sbjct: 489 DGSLFLDEKL 498
>UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosophila
melanogaster|Rep: Protein dachsous precursor - Drosophila
melanogaster (Fruit fly)
Length = 3503
Score = 194 bits (472), Expect = 2e-47
Identities = 252/977 (25%), Positives = 410/977 (41%), Gaps = 124/977 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L F+ V +T+ D NDN P+F S Y ++ NA VGT + +V A D D +NG+V Y
Sbjct: 213 LRGFMTVNITIQDVNDNQPIFNQSR-YFATVPENATVGTSVLQVYASDTDADENGLVEYA 271
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ R + F+I+P TG + + ++ E + H L V A D P E + A V+
Sbjct: 272 INRRQS-DKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLE---TTAFVS 327
Query: 557 IEVTRGTKGNKPDIPD-FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD--LLHG 613
I VT N+P I F+ + + G V +I V+D + + + L+G
Sbjct: 328 IRVT-DVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNG 386
Query: 614 YEEGVPFAVEERSGVITVVD-DLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
+ + S + +V L R Y VA + L + + + DVND
Sbjct: 387 GDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVND 446
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + + V + G ++ Q+ + G + L +
Sbjct: 447 NPPEFEQDLYHANVMEVAD--PGTSVLQVLAHDRDE--GLNSALTYSLAETPETHAQWFQ 502
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I + G I T+ +D E V ++TV+A + GV + V + I D NDN P+F+ +
Sbjct: 503 IDPQTGLITTRSHIDCETEPVPQLTVVAR-DGGVPPLSSTATVLVTIHDVNDNEPIFDQS 561
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEM--FDVDENTGVVK 847
Y + EN +G I + A+D D G NA+ YT+ GEG K + F+V +G +
Sbjct: 562 FYNVSVAENEPVGRCILK---VSASDPDCGVNAMVNYTI-GEGFKHLTEFEVRSASGEIC 617
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
G+ LD E++ Y+ ++A D GGLS+ A + K + + +N V RE
Sbjct: 618 IAGE-LDFERRSSYEFPVLATDRGGLSTTAMI----------KMQLTDVNDNRPVFYPRE 666
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
K++ + PK T I+ + A D D G GQ+
Sbjct: 667 YKVS-------LRESPKASSQAS----------------STPIVAVVATDPDYGNFGQVS 703
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLND 1027
Y + ++ E+ FV+ ++ R+ P LNISA DGGNL
Sbjct: 704 YRIVAGNEAGIFRIDRSTGEI---FVVRP---DMLSVRTQPMHM---LNISATDGGNLRS 754
Query: 1028 NISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
N VF+ D P+F+K YN+ V+E V+G V A D + + Y I
Sbjct: 755 NADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIY 814
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
D D F I +G + + LD E + + +L + A DVN
Sbjct: 815 SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQA--TLGEPPVYGHTQVNIEVEDVN 872
Query: 1146 DNSPKFYAFDELLEWKHPEADELS-------NHNFESVMMIPVYKATIEENAPIGTTVAK 1198
DN+P+F A ++ PE+ EL H+ +S V + ++E+ G +
Sbjct: 873 DNAPEFEA--SMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKES---GKGLFA 927
Query: 1199 VFANDTDFIGNGNGLILYSLPQRK----NQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
+ A I + + + Y QR + G+PSLS+ ++V V DV D +
Sbjct: 928 IDARSGHLILSQH--LDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVND-----NP 980
Query: 1255 PVFISRYYELEIEE--NVNAPVELVSLNLTEHYENFKMRYYILNE---------NDTDIR 1303
PVF Y + + E ++NA + V+ + + N ++ Y I++ + +D+
Sbjct: 981 PVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVS 1040
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD 1363
+ F I P +G +YL DRE +D Y++ V +A D
Sbjct: 1041 QHFGIFPNSGWIYLRAPLDRETRDRYQLTV-----------------LATDNGTPAAHAK 1083
Query: 1364 VKVVVRIKDVNDNSPKF 1380
+V+VR+ D NDN PKF
Sbjct: 1084 TRVIVRVLDANDNDPKF 1100
Score = 167 bits (407), Expect = 2e-39
Identities = 293/1241 (23%), Positives = 500/1241 (40%), Gaps = 147/1241 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D+D G L YE+ GN F ++S G + L K L E + F L +
Sbjct: 1577 IVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIG 1636
Query: 278 ASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P K + + + + ++N P F Y +I+EN+P+G VLQV A
Sbjct: 1637 AKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGA 1696
Query: 337 ENGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
EN +Y++ P G F +D + G +T R Q DRE+ +S + VY ++ N
Sbjct: 1697 ENANLSYEI--PAGVANDLFHVDWQRGIITTRGQ--FDRESQASYVLPVYVRDAN----- 1747
Query: 393 TFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
R+ L ++A ++ + D +G T N +++D + +T+ D
Sbjct: 1748 -----------RQSTLSSSAVRKQRS---SDSIG-DTSNGQHFD-----VATIYITVGDV 1787
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
NDN+P F P + Y S+ N++ G VI V A D D G N ++Y + + + + F
Sbjct: 1788 NDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSI---TGGNLGNKFS 1843
Query: 513 INPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP 571
I+ ++G +S R+ L ++ASD+ P R+ +TI V + + P
Sbjct: 1844 IDSSSGELSARPLDREQHSRYTLQIQASDR-GQPKSRQ-GHCNITIFV----EDQNDNAP 1897
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
F + Y V + +GTSV QI DA + E FA++ +SG+IT
Sbjct: 1898 RFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITT 1957
Query: 632 VDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
V L R + Y+F +A S ++V+D+ND R + P I V
Sbjct: 1958 VGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIF---ERYPYIGQVP 2014
Query: 690 E-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDRE 747
G + ++ + + G V L A V+ I G + + L E
Sbjct: 2015 ALIQPGQTLLKV--QALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASE 2072
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV--FEHATYEGFIMENSKIGTE 805
+ + V+A +KG + + + + I + PV F++ TY + ENS GT
Sbjct: 2073 SGKLLHLEVVAR-DKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTR 2131
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDS-LDREKKIMYK 862
+ +++ +G ++ FG G E + +D +G ++ LD ++
Sbjct: 2132 LLQVVALRS----DGRRQKVQFS-FGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPS 2186
Query: 863 LSLVARDTGGLSSEAELIIMIGDENDNKPEF-------------NQIEENSKVRIHRETK 909
+S ++R L E E+ ++ +N +Q E V + R
Sbjct: 2187 MSALSRGR-ALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTAD 2245
Query: 910 LNGTAGFT--IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
A + +IE++ +N + Q + + E GT + +++A D D+G N ++R
Sbjct: 2246 APFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLR 2305
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NL 1025
Y + + +A +E ++ ++++ R + ++L I A D G +
Sbjct: 2306 YHI-----VDGNHDNAFVIEPAFSGIVRT---NIVLDREI--RDIYKLKIIATDEGVPQM 2355
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
++RV + DVND+ P F V EA V+ + A D D LTY +
Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVD--TYPALTYRLG 2412
Query: 1086 PSDT-DLP----FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
T D+ F + +G L + LD E + +Y L V+A D
Sbjct: 2413 AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASD----AAHEARTVLTVR 2468
Query: 1141 XXDVNDNSPKFYAFDELLEWK-HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
D NDN+P F A + P E+S ++ V AT ++ + V +
Sbjct: 2469 VNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTV-NATDADSEGNNSKVIYI 2527
Query: 1200 F--ANDTDFIGNGNGLILYSLPQ-------------RKNQQNLGLPSLSSTAILMVTVAD 1244
A + + NG++ ++ + R ++ G P+L S+ +L V D
Sbjct: 2528 IEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQAND 2587
Query: 1245 VPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRR 1304
S + F+ Y +I E AP+ V L L + + + NE
Sbjct: 2588 -----NGSGRSQFLQNQYRAQISE--AAPLGSVVLQLGQDALDQSLAIIAGNEES----- 2635
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
F + ++ + LV+ DRE D Y K L H P L + +
Sbjct: 2636 AFEL-LQSKAIVLVKPLDRERNDLY---------KLRLVLSHPHGPPLISSLNSSS--GI 2683
Query: 1365 KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
V++ I D NDN P F + I AP Y + QL+
Sbjct: 2684 SVIITILDANDNFPIFDRSAK-YEAEISELAPLRYSIAQLQ 2723
Score = 144 bits (349), Expect = 2e-32
Identities = 132/495 (26%), Positives = 219/495 (44%), Gaps = 51/495 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSN-----LYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
E+L + V V + +LDAND+ P FV N + ++G V+ + AVD D G
Sbjct: 1527 ERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGD 1586
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PILE-----GRHALFVEASDQPAN 544
NG + Y++ + F+IN TG + + +S P E GR L + A D
Sbjct: 1587 NGQLTYEITGGNG---EGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH-GQ 1642
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--E 602
P ++ SL + I +G+ + P F+ A Y + NV G+ V Q+ E
Sbjct: 1643 PEPKKSSLNLHLI-----VQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAE 1697
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
++SY++ G + F V+ + G+IT R ++ Y N S ++++
Sbjct: 1698 NANLSYEIPAGVANDL-FHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQ-STLSSS 1755
Query: 663 TVHVVDVNDERGVLLKGAHSPI------IFHVKENSA----GAAIGQ---------IFHT 703
V +D G G H + + V +NS G+ G + HT
Sbjct: 1756 AVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHT 1815
Query: 704 NMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKG 763
++S G ++ + +I + +PLDRE+ Y + + A
Sbjct: 1816 VVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQ 1875
Query: 764 VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA 823
S G +TI++ED+NDN P F+ + Y G + E++ +GT + I A DAD G NA
Sbjct: 1876 PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQ---ISAVDADLGVNA 1932
Query: 824 LFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL---SSEAELI 880
+Y+L E + F +D +G++ +G LDRE + Y ++A D G S+ +
Sbjct: 1933 RLVYSLANETQWQFAIDGQSGLITTVG-KLDRELQASYNFMVLATDGGRYEVRSATVPVQ 1991
Query: 881 IMIGDENDNKPEFNQ 895
I + D NDN+P F +
Sbjct: 1992 INVLDINDNRPIFER 2006
Score = 132 bits (318), Expect = 9e-29
Identities = 188/730 (25%), Positives = 297/730 (40%), Gaps = 80/730 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V ++++DA P+F + Y + +K + GTV+G V A D+ V Y +
Sbjct: 760 VFLSIIDAMQRPPIFEKAR-YNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP 818
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F I N+G + +A+ E + + + P Y V IEV +
Sbjct: 819 ---DGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPV--YGHTQVNIEV----E 869
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAV 622
+ P+F + V + +G + +D + V+Y L+ +G+ FA+
Sbjct: 870 DVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGL-FAI 928
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDERGVLLKGA 680
+ RSG + + L Y V + S+ TN T V V DVND V K
Sbjct: 929 DARSGHLILSQHLD-YESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDE 987
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI--ANQQDVTDDIAIAE---- 734
+S V + + + QI N S + + + I A +VT+ I+ ++
Sbjct: 988 YS-----VNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQH 1042
Query: 735 ------DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G I+ + PLDRE RD Y++TV+A N G + +V + + D NDN P F+
Sbjct: 1043 FGIFPNSGWIYLRAPLDRETRDRYQLTVLATDN-GTPAAHAKTRVIVRVLDANDNDPKFQ 1101
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ YE I EN + G+ + ++ A+D D G NA Y+L F V TG +
Sbjct: 1102 KSKYEFRIEENLRRGSVV---GVVTASDLDLGENAAIRYSLLPINSS-FQVHPVTGEIS- 1156
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ LDRE + +Y L + ARD G S+ + I + D NDN PE +E+ V R
Sbjct: 1157 TREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQED--VVSVR 1214
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E + GT ++ V+ A+D D +N I +I+K DS +G
Sbjct: 1215 EEQPPGT---EVVRVR-----AVDRDH-------GQNASITYSIVK----GRDSDGHGLF 1255
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR-LNISALDGGNL 1025
+ S V L + + R V G+ PP R L + LD L
Sbjct: 1256 SIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGN-------PPRETVRMLRVEVLD---L 1305
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
NDN R + F V + V R V + + ++ +TY +
Sbjct: 1306 NDN---RPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLN 1362
Query: 1086 PSDTDL---PFEISPLTGVLSVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXX 1141
P DL F+I +G L V LDRE + ++ L + A D
Sbjct: 1363 PLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEV 1422
Query: 1142 XDVNDNSPKF 1151
DVNDN+P++
Sbjct: 1423 ADVNDNAPEW 1432
Score = 127 bits (306), Expect = 3e-27
Identities = 175/750 (23%), Positives = 301/750 (40%), Gaps = 86/750 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD--PDLGQNGM-------- 494
+ V +LD NDN P F S+L F ++ +A +G V+G + ++ D+ +N +
Sbjct: 1298 LRVEVLDLNDNRPTFTSSSLV-FRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLR 1356
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSL 552
V Y L + I + F I+ ++G + VA ++ L + A D A+ + + S
Sbjct: 1357 VTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQS-SA 1415
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
V IEV N P+ P P + V +GT + DA D+ Y L
Sbjct: 1416 ITVKIEVA-DVNDNAPEWPQ---DPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRL 1471
Query: 611 LHGY-------EEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS--IVT 660
+ + E+ + F ++ +G +++ L Y AL +++N++ + T
Sbjct: 1472 IRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQT 1531
Query: 661 NATVH--VVDVNDERGVLLK----GAHSPIIFHVKENSAGAAIGQIFHTNMSS------- 707
+ TV ++D ND + G + +F G + I + S
Sbjct: 1532 SVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLT 1591
Query: 708 --IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
I G G G RF I +Q + + + T D EK + + + A+ +
Sbjct: 1592 YEITG-GNGEGRFRINSQTGIIELVKSLPPATE------DVEKGGRFNLIIGAKDHGQPE 1644
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ + ++ ++NPP F A Y I+EN G+ + + A NA
Sbjct: 1645 PKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQ---VTAKSLHGAENANL 1701
Query: 826 MYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
Y + G ++F VD G++ G DRE + Y L + RD S+ + +
Sbjct: 1702 SYEIPAGVANDLFHVDWQRGIITTRG-QFDRESQASYVLPVYVRDANRQSTLSSSAVRKQ 1760
Query: 885 DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENI 944
+D+ + + + I+ G E +P + + L V PEN
Sbjct: 1761 RSSDSIGDTSNGQHFDVATIYITV---GDVNDNSPEFRPGSCYGLSV---------PENS 1808
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
G I + A DLD G N + Y + + + E+ + E+H
Sbjct: 1809 EPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPLDREQH------ 1861
Query: 1005 RSLPPESEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
S + L I A D G + + ++ +FV+D ND+ P FK + Y +V+E
Sbjct: 1862 ------SRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLG 1915
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ ++ A DAD G NA L Y + ++T F I +G+++ G+LDRE + Y V+
Sbjct: 1916 TSVVQISAVDADLGVNARLVYSL-ANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVL 1974
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
A D G D+NDN P F
Sbjct: 1975 ATDGGRYEVRSATVPVQINVLDINDNRPIF 2004
Score = 124 bits (299), Expect = 2e-26
Identities = 178/712 (25%), Positives = 287/712 (40%), Gaps = 75/712 (10%)
Query: 215 PEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT 271
P IH + D D G A L Y + GN FS+DS +G L LD E Q +
Sbjct: 1810 PGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARP---LDRE---QHSR 1863
Query: 272 FVLQVQASQLNNPLKTAQARVEIELL--DLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ LQ+QAS P K+ Q I + D NDN P F++ Y S+ E+ P G SV+Q+
Sbjct: 1864 YTLQIQASDRGQP-KSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQIS 1922
Query: 330 ATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
A D D G N Y L ++ + F+ID +SG +T + LDRE +S V A +
Sbjct: 1923 AVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGK--LDRELQASYNFMVLATDGGR 1980
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPL-EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEV 447
V + +I + N P+ E+ Y+ + + + + V+
Sbjct: 1981 YEVRSATVPVQI---NVLDINDNRPIFERYPYI---------GQVPALIQPGQTLLKVQA 2028
Query: 448 TLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTI 507
D N + N ++ + ++ G + A ++G +L+ L +
Sbjct: 2029 LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLH-------LEV 2081
Query: 508 TSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ K NP ++ + E I E G L + E S + V +
Sbjct: 2082 VARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD 2141
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN-------DAFEQNDVSY----DLLHG 613
G + + GA E + + + + G+IRVN D F +S LH
Sbjct: 2142 GRRQKVQFSFGAGNEDGI---LSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALH- 2197
Query: 614 YEEGVPFAVEE------RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
YEE + + EE RS + N + V + A+ + + V+
Sbjct: 2198 YEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVI 2257
Query: 668 DVNDERGVLLKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQD 725
++ DE K + + V E N+ G + Q+ H S N +R+ ++ D
Sbjct: 2258 ELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQV-HAFDSDAGSN--ARLRYHIVDGNHD 2314
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I A G + T LDRE RD+Y++ +IA ++GV G + + I D NDN P
Sbjct: 2315 NAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIAT-DEGVPQMTGTATIRVQIVDVNDNQP 2373
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY----TLFGEGKEMFDVDE 841
F + E +++G I I A D D + T+ E +F +D
Sbjct: 2374 TFPPNNLV-TVSEATELGAVI---TSISANDVDTYPALTYRLGAESTVDIENMSIFALDR 2429
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+G + + LD E + Y+L ++A D + L + + DENDN P F
Sbjct: 2430 YSGKL-VLKRRLDYELQQEYELDVIASDAAH-EARTVLTVRVNDENDNAPVF 2479
Score = 124 bits (298), Expect = 2e-26
Identities = 214/896 (23%), Positives = 362/896 (40%), Gaps = 116/896 (12%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + + D NDN P S++ GT + +V+AVD D GQN + Y + +
Sbjct: 1187 VPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKG 1246
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F I+P +G + E R + L V ASD NP R ++ ++ +EV
Sbjct: 1247 RDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASD-GGNPP--RETVRMLRVEVL 1303
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI------------RVNDAFEQNDVSY 608
N+ P F + F V + +G VG I V ++FE V+Y
Sbjct: 1304 -DLNDNR---PTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTY 1359
Query: 609 DLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
L ++ + F ++ SG + V L R + + E AL A+ + ++A
Sbjct: 1360 TLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVK 1419
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIAN--- 722
++V D + PI V E +G I H ++ GT G++++ +
Sbjct: 1420 IEVADVNDNAPEWPQDPIDLQVSE---ATPVGTIIHNFTATDADTGTNGDLQYRLIRYFP 1476
Query: 723 QQDVTDDIAI------AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
Q + + + A+ + G + Q PLD E Y + V A ++ VT+
Sbjct: 1477 QLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVR 1536
Query: 777 IE--DENDNPPVFEHATYEG------FIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+ D ND+ P F G FI + ++IG + I A D D G N Y
Sbjct: 1537 LRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH---IVAVDEDSGDNGQLTYE 1593
Query: 829 LF-GEGKEMFDVDENTGVVKFIGD----SLDREKKIMYKLSLVARDTG---GLSSEAELI 880
+ G G+ F ++ TG+++ + + D EK + L + A+D G S L
Sbjct: 1594 ITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLH 1653
Query: 881 IMIGDENDNKPEFNQIEENSKVRIHRETKL-NGTAGFTIIEVKPKNKFALDVDQLGPLFL 939
+++ ++N P F Q ++R T L N +G +++V K+ + L
Sbjct: 1654 LIVQGSHNNPPRFLQ-------AVYRATILENVPSGSFVLQVTAKSLHGAENANLS---- 1702
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IP G L +D G+ R +F+ E + A V +V + +
Sbjct: 1703 --YEIPAGVA-NDLFHVDWQRGII-TTRGQFDRE---------SQASYVLPVYV-RDANR 1748
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK-TWYNFNVEEAQ 1058
++ S + +I G D ++ + V DVND+ P F+ + Y +V E
Sbjct: 1749 QSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPE-N 1807
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
V+ V A+D D G NA+L Y I + F I +G LS LDRE +Y L
Sbjct: 1808 SEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-PLDREQHSRYTL 1866
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
+ A D G D NDN+P+F +LS
Sbjct: 1867 QIQASDRGQPKSRQGHCNITIFVEDQNDNAPRF---------------KLSK-------- 1903
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
Y +++E+AP+GT+V ++ A D D N ++YSL Q ++ + L
Sbjct: 1904 ---YTGSVQEDAPLGTSVVQISAVDADL--GVNARLVYSLANETQWQF----AIDGQSGL 1954
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYI 1294
+ TV + E++ S + ++ + PV++ L++ ++ F+ YI
Sbjct: 1955 ITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYI 2010
Score = 120 bits (289), Expect = 3e-25
Identities = 125/476 (26%), Positives = 205/476 (43%), Gaps = 46/476 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG-----TVIGKVKAVDPDLGQNGMVLYDL 499
+++ L D NDN PVF P Y+ S++ + K T I V A DPD G G V Y +
Sbjct: 648 IKMQLTDVNDNRPVFYPRE-YKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRI 706
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVV 555
+ I F+I+ +TG + V +L R H L + A+D + R + AVV
Sbjct: 707 VAGNEAGI---FRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATD---GGNLRSNADAVV 760
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
+ + + +P P F A Y ++V ++ GT VG + D ++ V Y + G
Sbjct: 761 FLSIIDAMQ--RP--PIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSG 816
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+G F++E SG I + L + A + T + V DVND
Sbjct: 817 DPDGY-FSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNA 875
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
S + V E++ A H + +G V + + + A
Sbjct: 876 PEF---EASMVRISVPESAELGAPLYAAHAHDKD--SGSSGQVTYSLVKESGKGLFAIDA 930
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G + + LD E + + V A + GV S + + + ++D NDNPPVFE Y
Sbjct: 931 RSGHLILSQHLDYESSQRHTLIVTAT-DGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYS 989
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-------MFDVDENTGVV 846
+ E+ I +I + A+D D G NA Y + G + DV ++ G+
Sbjct: 990 VNVSESRSINAQIIQ---VNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIF 1046
Query: 847 K-----FIGDSLDREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDNKPEFNQ 895
++ LDRE + Y+L+++A D G ++ A+ +I+ + D NDN P+F +
Sbjct: 1047 PNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQK 1102
Score = 114 bits (274), Expect = 2e-23
Identities = 110/423 (26%), Positives = 184/423 (43%), Gaps = 39/423 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ I II++NA DLD+G N +I Y + + S + +V ++F I G
Sbjct: 992 VSESRSINAQIIQVNASDLDTGNNARITYRI-VDAGVDNVTNSISSSDVSQHFGIFPNSG 1050
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
+ + L E+ ++L + A D G + RV V+ D ND+ P F+K+ Y F +E
Sbjct: 1051 WIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIE 1110
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E V+G V A+D D G+NA + Y + P ++ F++ P+TG +S LDRE +
Sbjct: 1111 ENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSS--FQVHPVTGEISTREPLDRELREL 1168
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE---LLEWKHPEADEL---- 1168
Y L V ARD G DVNDN+P+ E + + P E+
Sbjct: 1169 YDLVVEARDQGTPVRSARVPVRIHVS-DVNDNAPEIADPQEDVVSVREEQPPGTEVVRVR 1227
Query: 1169 ---SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
+H + + + K + + + T + + +Y L +
Sbjct: 1228 AVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDG 1287
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN------------VNAP 1273
G P + +L V V D+ D ++P F S + E+ + P
Sbjct: 1288 --GNPPRETVRMLRVEVLDLND-----NRPTFTSSSLVFRVREDAALGHVVGSISPIERP 1340
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTD-IRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
++V ++ E +E+ ++ Y LN D I F ID +G L + R DREV+ + +
Sbjct: 1341 ADVVRNSVEESFEDLRVTY-TLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLE 1399
Query: 1333 VRA 1335
+RA
Sbjct: 1400 IRA 1402
Score = 102 bits (244), Expect = 9e-20
Identities = 124/480 (25%), Positives = 203/480 (42%), Gaps = 37/480 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLY-EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ- 500
+ V VT+ D NDN P F ++++ EF + +V + + A D DL Y++
Sbjct: 105 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTL--LPARDLDLEPYNTQRYNIVS 162
Query: 501 -RTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVV 555
++ S + + + S L+ ++L +EA D P R + +
Sbjct: 163 GNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDG-GTPPLRGFMTVNI 221
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHG 613
TI+ + P F + Y V N +GTSV Q+ +D A E V Y +
Sbjct: 222 TIQDVNDNQ------PIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRR 275
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
+ F ++ R+G I + L + +++ VA L ++ V DVND
Sbjct: 276 QSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVND 335
Query: 672 ERG----VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ + L SP I + A + + + Y N + + T
Sbjct: 336 NQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTT 395
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
D +I + PLDRE Y ++V+A +KG + + I D NDNPP F
Sbjct: 396 RDNSIY---LVIVHLPLDREIVSNYTLSVVAT-DKGTPPLHASKSIFLRITDVNDNPPEF 451
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTG 844
E Y +ME + GT + + A D DEG N+ Y+L + + F +D TG
Sbjct: 452 EQDLYHANVMEVADPGTSVLQ---VLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTG 508
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ +D E + + +L++VARD G LSS A +++ I D NDN+P F+Q N V
Sbjct: 509 LIT-TRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSV 567
Score = 102 bits (244), Expect = 9e-20
Identities = 162/688 (23%), Positives = 273/688 (39%), Gaps = 55/688 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + + D NDN P F +LY ++ A GT + +V A D D G N + Y L T
Sbjct: 436 SIFLRITDVNDNPPEF-EQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETP 494
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTR 561
T F+I+P TG ++ E L V A D P S A V + +
Sbjct: 495 E-THAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLS---STATVLVTI-H 549
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVP 619
N+ P F + Y V N +G + ++ + D V+Y + G++
Sbjct: 550 DVNDNE---PIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTE 606
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F V SG I + +L R Y+F +A + LS + + DVND R V
Sbjct: 607 FEVRSASGEICIAGELDFERRSSYEFPVLA-TDRGGLSTTAMIKMQLTDVNDNRPVFYPR 665
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ + + S+ A+ I + YGN G V + I + G I
Sbjct: 666 EYKVSLRESPKASSQASSTPIVAVVATDPDYGN-FGQVSYRIVAGNEAGIFRIDRSTGEI 724
Query: 739 FTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
F +P L + ++ + + A + S A V + I D PP+FE A Y ++
Sbjct: 725 FVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV-VFLSIIDAMQRPPIFEKARYNYYV 783
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDR 855
E+ GT + + A D + Y+++ G+ F ++ N+G ++ I LD
Sbjct: 784 KEDIPRGTVV---GSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR-IAKPLDH 839
Query: 856 EKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFN------QIEENSKV-----R 903
E K L++ A + ++ I + D NDN PEF + E++++
Sbjct: 840 EAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYA 899
Query: 904 IHRETKLNGTAG---FTIIEVKPKNKFALDVDQLGPLFLIP----ENIPIGTTIIKLNAL 956
H K +G++G +++++ K FA+D + G L L E+ T I+
Sbjct: 900 AHAHDKDSGSSGQVTYSLVKESGKGLFAIDA-RSGHLILSQHLDYESSQRHTLIVTATDG 958
Query: 957 DLDS-GLNGQIRYEFNSEVYIPP-SKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
+ S N I + PP + ++ V IN + V A L + R
Sbjct: 959 GVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQV-NASDLDTGNNAR 1017
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKT-WYNFNVEEAQYTR-----RVLGKVD 1068
+ +D G DN++ + DV+ HF +F + W + TR VL +
Sbjct: 1018 ITYRIVDAG--VDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDN 1075
Query: 1069 ATDADFGQNANLTYFIQPSDTDLPFEIS 1096
T A + + + +D D F+ S
Sbjct: 1076 GTPAAHAKTRVIVRVLDANDNDPKFQKS 1103
Score = 95.5 bits (227), Expect = 1e-17
Identities = 97/342 (28%), Positives = 152/342 (44%), Gaps = 43/342 (12%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP--------------TGEKAFI 118
G+ +S L++ V ++DVNDN P+F Y V V E TG A I
Sbjct: 959 GVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARI 1018
Query: 119 -FLIAPIG-PSLTIPLT---VPRGLTIFKDIR-AFDRDKPNTPNSDVHYSIVSGNDDGHF 172
+ I G ++T ++ V + IF + + R + D + V D+G
Sbjct: 1019 TYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNG-- 1076
Query: 173 ALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGA 229
++H ++ +VLD + D +FQ RI + + + + D DLG A
Sbjct: 1077 -TPAAHAKTRVIVRVLDANDNDPKFQKSKYEF--RIEENLRRGSVVGVVTASDLDLGENA 1133
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+RY L+ N F + V G + + LD + + L V+A P+++A+
Sbjct: 1134 AIRYSLLPINSS--FQVHPVTGEISTREPLDRELRE-----LYDLVVEARDQGTPVRSAR 1186
Query: 290 ARVEIELLDLNDNLPEFEVDFYNI-SIVENLPNGFSVLQVMATDKDQGENGEFTYQL--- 345
V I + D+NDN PE ++ S+ E P G V++V A D+D G+N TY +
Sbjct: 1187 VPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKG 1246
Query: 346 --DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G FSIDP SG +R + VLD E S R+ V A +
Sbjct: 1247 RDSDGHGLFSIDPTSG--VIRTRVVLDHEERSIYRLGVAASD 1286
Score = 93.1 bits (221), Expect = 5e-17
Identities = 118/490 (24%), Positives = 209/490 (42%), Gaps = 51/490 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + + V + D NDN PVF + Y ++ + + I +V A D D G N + Y
Sbjct: 963 LSTNLTILVDVQDVNDNPPVF-EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYR 1021
Query: 499 L---------QRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPS 546
+ S+ ++ F I PN+G + + +P+ R+ L V A+D P+
Sbjct: 1022 IVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYL-RAPLDRETRDRYQLTVLATDN-GTPA 1079
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQN 604
+ +V R N D P F + YEF + N+ G+ VG + + D E
Sbjct: 1080 AHAKTRVIV-----RVLDANDND-PKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENA 1133
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL-SIVTNAT 663
+ Y LL F V +G I+ + L R R +YD A + + S
Sbjct: 1134 AIRYSLL---PINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVR 1190
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+HV DVND + ++ +E G + ++ + +G ++ + I
Sbjct: 1191 IHVSDVND-NAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRD--HGQ-NASITYSIVKG 1246
Query: 724 QDVTDDIAIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+D + D G I T+ LD E+R +YR+ V A + G + + + + D
Sbjct: 1247 RDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAAS-DGGNPPRETVRMLRVEVLDL 1305
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEI-------KMDNIIKATDADEGTNALFMYTLFGEG 833
NDN P F ++ + E++ +G + + ++++ + + + YTL
Sbjct: 1306 NDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLT 1365
Query: 834 KEM----FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT----GGLSSEAELIIMIGD 885
K++ FD+D ++G + + LDRE + ++L + A DT SS + I + D
Sbjct: 1366 KDLIEAAFDIDRHSGNL-VVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVAD 1424
Query: 886 ENDNKPEFNQ 895
NDN PE+ Q
Sbjct: 1425 VNDNAPEWPQ 1434
Score = 91.5 bits (217), Expect = 2e-16
Identities = 163/709 (22%), Positives = 296/709 (41%), Gaps = 89/709 (12%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q+ + V ++D NDN P F P+NL S + ++G VI + A D D
Sbjct: 2354 QMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEAT--ELGAVITSISANDVDTYPALTYRL 2411
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAV- 554
+ T ++ S F ++ +G + + L+ + L V ASD E R L V
Sbjct: 2412 GAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEARTVLTVR 2468
Query: 555 VTIEVTRGTKGNKPDIPDFMGA-PYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS--YDLL 611
V E P + P + ++ + + + DA + + S ++
Sbjct: 2469 VNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYII 2528
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMY---DFEAVALQENANLSIVTNATVHVVD 668
+EG F+V +GV++V ++SR + D+ + ++A + ++T+ V
Sbjct: 2529 EPAQEG--FSVHPSNGVVSV--NMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQ 2584
Query: 669 VNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
ND + + + E + G+ + Q+ + ++ + N++
Sbjct: 2585 ANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQ-------SLAIIAGNEESAF 2637
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKG------VISGAGIYQVTIYIEDEN 781
+ + + I KPLDRE+ D+Y++ ++ G + S +GI V I I D N
Sbjct: 2638 E---LLQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI-SVIITILDAN 2693
Query: 782 DNPPVFEH-ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV 839
DN P+F+ A YE I E + + I I A D + N+ +Y + G + MF +
Sbjct: 2694 DNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDA-DQENTPNSEVVYDITSGNDEHMFTI 2752
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
D TGV+ F+ + LD D+G S E LII D + +P + +
Sbjct: 2753 DLVTGVL-FVNNRLDY-------------DSGAKSYE--LIIRACDSHHQRPLCSL--QP 2794
Query: 900 SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD 959
++ +H E + F + E + + EN P+G+++ + +A DLD
Sbjct: 2795 FRLELHDEN--DNEPKFPLTEY---------------VHFLAENEPVGSSVFRAHASDLD 2837
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNI 1017
G GQ+ Y PS S+ + F ++ G V A E R + +
Sbjct: 2838 KGPFGQLNYSIGP----APSDESS-----WKMFRVDSESGLVTSAFVFDYEQRQRYDMEL 2888
Query: 1018 SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR--VLGKVDATDADFG 1075
A D G +++VRV ++ ++ P F + Y F + A + V+G+V ATD+D G
Sbjct: 2889 LASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSG 2948
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+ + Y Q S F+++ +G + + +L + + L + RD
Sbjct: 2949 PDGRVVY--QLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLYMDGRD 2995
Score = 87.0 bits (206), Expect = 3e-15
Identities = 89/304 (29%), Positives = 133/304 (43%), Gaps = 21/304 (6%)
Query: 861 YKLSLVARDTGGLSSEAELIIMI--GDENDNKPEFNQIEENSKVRIHRETK--------- 909
Y++ + D GG+ S II+ G E D + E +KV++ RET+
Sbjct: 41 YQIGYIG-DFGGIDSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIP 99
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L+G ++ VK +N A Q PEN P L A DLD RY
Sbjct: 100 LSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYN 159
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LND 1027
S +LS+ ++ + G + R P + L I ALDGG L
Sbjct: 160 IVSGNVNDAFRLSSHRERDGVLYLDLQISG--FLDRETTPG--YSLLIEALDGGTPPLRG 215
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--Q 1085
++V + ++DVND+ P+F ++ Y V E + +V A+D D +N + Y I +
Sbjct: 216 FMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRR 275
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
SD + F I P TG + +N LD ET++ + L VVA+D+G DVN
Sbjct: 276 QSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHG-EQPLETTAFVSIRVTDVN 334
Query: 1146 DNSP 1149
DN P
Sbjct: 335 DNQP 338
Score = 84.6 bits (200), Expect = 2e-14
Identities = 120/534 (22%), Positives = 204/534 (38%), Gaps = 39/534 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAP-IGPSLTI 130
G+ +S+ +V V I DVNDN PIF + Y+V+V E P G + P G + +
Sbjct: 534 GVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMV 593
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
T+ G + ++ + S + A + + K+
Sbjct: 594 NYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLT 653
Query: 191 DAGD-------KEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGVGATLRYELISGNDRK 242
D D +E+++ + S K + P + A D D G + Y +++GN+
Sbjct: 654 DVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAG 713
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+F +D G +F+ + L +L + A+ N A A V + ++D
Sbjct: 714 IFRIDRSTGEIFVVRPDMLSVRTQPM---HMLNISATDGGNLRSNADAVVFLSIIDAMQR 770
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P FE YN + E++P G V V+A D Y + DP G FSI+ SG
Sbjct: 771 PPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSG- 829
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYV 420
+R LD EA S + + + A P V G + + E A + + +
Sbjct: 830 -NIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVP 888
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTL----------LDANDNNPVFVPSNLYEFSMK 470
++G +D+ S V +L +DA + + YE S +
Sbjct: 889 ESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQR 948
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG 530
V G V P L N +L D+Q ++ +P + +V+V+ES +
Sbjct: 949 HTLIVTATDGGV----PSLSTNLTILVDVQDVND----NPPVFEKDEYSVNVSESRSINA 1000
Query: 531 RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG-NKPDIPDFMGA-PYEFWV 582
+ + V ASD + R + +V V T + D+ G P W+
Sbjct: 1001 Q-IIQVNASDLDTG-NNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWI 1052
Score = 83.4 bits (197), Expect = 4e-14
Identities = 84/336 (25%), Positives = 146/336 (43%), Gaps = 29/336 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+ G + +++V + I+DVNDN PIF + Y TV E G +
Sbjct: 206 LDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADEN 265
Query: 130 --IPLTVPRGLT----IFK-DIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
+ + R + +F+ D R + + ++H +V D G LE++
Sbjct: 266 GLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETT-- 323
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMA--SGKRIHKEIL---FPEPIHAIDQDLGVGATLRYE 234
+ +V D + ++ ++ + +I + F I D D
Sbjct: 324 -AFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNV 382
Query: 235 LISGNDRKLFSLDSVNGSLFLE-KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
++G D F+L + + S++L L LD E + + L V A+ P A +
Sbjct: 383 TLNGGDGH-FALTTRDNSIYLVIVHLPLDREI---VSNYTLSVVATDKGTPPLHASKSIF 438
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-- 351
+ + D+NDN PEFE D Y+ +++E G SVLQV+A D+D+G N TY L +
Sbjct: 439 LRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHA 498
Query: 352 --FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F IDP++G +T R+ +D E ++ V A++
Sbjct: 499 QWFQIDPQTGLITTRSH--IDCETEPVPQLTVVARD 532
Score = 81.0 bits (191), Expect = 2e-13
Identities = 94/347 (27%), Positives = 149/347 (42%), Gaps = 33/347 (9%)
Query: 67 LVRIGAGLNQISAY--LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--A 122
L+ I A L + Y V + +EDVNDN P F + ++V E G +
Sbjct: 846 LLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDK 905
Query: 123 PIGPS--LTIPLTVPRGLTIFK-DIRAFD---RDKPNTPNSDVHYSIVSGNDDGHFALES 176
G S +T L G +F D R+ + +S H IV+ D G +L +
Sbjct: 906 DSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLST 965
Query: 177 SHKPVLLLRKVLDYD-AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
+ ++ ++ V D +K+ V ++ + I+ +I+ ++A D D G A + Y +
Sbjct: 966 NLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQII---QVNASDLDTGNNARITYRI 1022
Query: 236 I-SGNDRKLFSLDSVN-----------GSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
+ +G D S+ S + G ++L LD + Q L V A+
Sbjct: 1023 VDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQ-----LTVLATDNGT 1077
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
P A+ RV + +LD NDN P+F+ Y I ENL G V V A+D D GEN Y
Sbjct: 1078 PAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRY 1137
Query: 344 QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
L +F + P +G ++ R LDRE + V A++ V
Sbjct: 1138 SLLPINSSFQVHPVTGEISTREP--LDRELRELYDLVVEARDQGTPV 1182
Score = 73.7 bits (173), Expect = 3e-11
Identities = 51/170 (30%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
DQ+ + + Y++ SGND +F++D V G LF+ LD D+ ++ +++ S
Sbjct: 2728 DQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDS--GAKSYELIIRACDSHH 2785
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
PL + Q +EL D NDN P+F + Y + EN P G SV + A+D D+G G+
Sbjct: 2786 QRPLCSLQP-FRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQL 2844
Query: 342 TYQL------DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y + + F +D SG +T + V D E M++ A +
Sbjct: 2845 NYSIGPAPSDESSWKMFRVDSESGLVT--SAFVFDYEQRQRYDMELLASD 2892
Score = 71.7 bits (168), Expect = 1e-10
Identities = 161/642 (25%), Positives = 257/642 (40%), Gaps = 87/642 (13%)
Query: 718 FLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
++I + V D+AI G I T+ LDRE R Y + I +SG I +V +
Sbjct: 58 YIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIP------LSGRNI-RVLVT 110
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKE 835
++DENDN P F + EN+ E+K ++ A D D E N + G +
Sbjct: 111 VKDENDNAPTFPQTSMHIEFPENTP--REVKR-TLLPARDLDLEPYNTQRYNIVSGNVND 167
Query: 836 MFDVD---ENTGVVKF---IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEN 887
F + E GV+ I LDRE Y L + A D G L + I I D N
Sbjct: 168 AFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVN 227
Query: 888 DNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIG 947
DN+P FNQ R N T G ++++V +A D D EN G
Sbjct: 228 DNQPIFNQ------SRYFATVPENATVGTSVLQV-----YASDTD-------ADEN---G 266
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
+N D +I +YI + L + E+ V+ + HG
Sbjct: 267 LVEYAINRRQSDKEQMFRIDPR-TGAIYINKA-LDFETKELHELVVVAKDHG------EQ 318
Query: 1008 PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
P E+ ++I D + I+V +F+ D D P + + + ++ R+
Sbjct: 319 PLETTAFVSIRVTDVNDNQPTINV-IFLSD--DASPKISE-----SAQPGEFVARISVHD 370
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
+ ++ N N+T L + + V+ V+ LDRE Y L+VVA D G
Sbjct: 371 PDSKTEYA-NVNVTLNGGDGHFALTTRDNSIYLVI-VHLPLDREIVSNYTLSVVATDKG- 427
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE 1187
DVNDN P+F + H E+++ SV+ + +
Sbjct: 428 TPPLHASKSIFLRITDVNDNPPEFEQ-----DLYHANVMEVADPG-TSVLQVLAHDRDEG 481
Query: 1188 ENAPIGTTVAKVFANDTDF--IGNGNGLI---------LYSLPQ-RKNQQNLGLPSLSST 1235
N+ + ++A+ + I GLI +PQ ++ G+P LSST
Sbjct: 482 LNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST 541
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYY 1293
A ++VT+ DV D ++P+F +Y + + EN V + VS + + N M Y
Sbjct: 542 ATVLVTIHDVND-----NEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVN-AMVNY 595
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ E + F + +G + + D E + +YE V A
Sbjct: 596 TIGEGFKHLTE-FEVRSASGEICIAGELDFERRSSYEFPVLA 636
Score = 71.7 bits (168), Expect = 1e-10
Identities = 61/185 (32%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSV---NGSLFLEKELD--LDAEHNLQANTFVL 274
A D DL T RY ++SGN F L S +G L+L+ ++ LD E + L
Sbjct: 145 ARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRE---TTPGYSL 201
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
++A P V I + D+NDN P F Y ++ EN G SVLQV A+D D
Sbjct: 202 LIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTD 261
Query: 335 QGENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
ENG Y ++ D + F IDPR+G + + LD E + V AK+
Sbjct: 262 ADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINK--ALDFETKELHELVVVAKDHGEQP 319
Query: 391 VGTFA 395
+ T A
Sbjct: 320 LETTA 324
Score = 66.9 bits (156), Expect = 4e-09
Identities = 83/317 (26%), Positives = 131/317 (41%), Gaps = 31/317 (9%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
+V G + A S+ + I DVNDN P F YH V E+ G L
Sbjct: 421 VVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDE 480
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPN---TPNSDVHYSI-------VSGNDDGHFALES 176
L LT T + F D T S + V D G L S
Sbjct: 481 GLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSS 540
Query: 177 SHKPVLLLRKVLDYDA-GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
+ ++ + V D + D+ F V +A + + + IL + A D D GV A + Y +
Sbjct: 541 TATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCIL---KVSASDPDCGVNAMVNYTI 597
Query: 236 ISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
G F + S +G + + ELD + + +++ V A+ TA +++
Sbjct: 598 GEGFKHLTEFEVRSASGEICIAGELDFE-----RRSSYEFPVLATDRGGLSTTAM--IKM 650
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFS------VLQVMATDKDQGENGEFTYQL--D 346
+L D+NDN P F Y +S+ E+ P S ++ V+ATD D G G+ +Y++
Sbjct: 651 QLTDVNDNRPVFYPREYKVSLRES-PKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAG 709
Query: 347 DPKGAFSIDPRSGWLTV 363
+ G F ID +G + V
Sbjct: 710 NEAGIFRIDRSTGEIFV 726
Score = 66.1 bits (154), Expect = 7e-09
Identities = 74/280 (26%), Positives = 122/280 (43%), Gaps = 27/280 (9%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
+DL V TL L F +D +G+L + + LD + + + L AS N
Sbjct: 1353 EDLRVTYTLN-PLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS--N 1409
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NP +A V+IE+ D+NDN PE+ D ++ + E P G + ATD D G NG+
Sbjct: 1410 NPQSSA-ITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQ 1468
Query: 343 YQL-----------DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
Y+L + F +D +G L++ Q LD EA + V A + + +V
Sbjct: 1469 YRLIRYFPQLNESQEQAMSLFRMDSLTGALSL--QAPLDFEAVQEYLLIVQALDQSSNVT 1526
Query: 392 GTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL- 450
S + R + L+ N +V P+ G KT ++ D + V + +
Sbjct: 1527 ERLQTSVTV---RLRILDAND--HAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVD 1581
Query: 451 -DANDNNPVF--VPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
D+ DN + + E + N++ G +I VK++ P
Sbjct: 1582 EDSGDNGQLTYEITGGNGEGRFRINSQTG-IIELVKSLPP 1620
Score = 65.3 bits (152), Expect = 1e-08
Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 12/171 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
A D+D G+ + L Y L + + F +D G + +D + E Q L V
Sbjct: 475 AHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQ-----LTVV 529
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P ++ A V + + D+NDN P F+ FYN+S+ EN P G +L+V A+D D G
Sbjct: 530 ARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGV 589
Query: 338 NGEFTYQLDD---PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y + + F + SG + + + LD E SS V A +
Sbjct: 590 NAMVNYTIGEGFKHLTEFEVRSASGEICIAGE--LDFERRSSYEFPVLATD 638
Score = 64.9 bits (151), Expect = 2e-08
Identities = 89/349 (25%), Positives = 139/349 (39%), Gaps = 34/349 (9%)
Query: 51 NVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIF-LDTPYHVTVDEL 109
++ K RL G L+ + LN S +SV + I D NDN PIF Y + EL
Sbjct: 2657 DLYKLRLVLSHPHGPPLI---SSLNSSSG-ISVIITILDANDNFPIFDRSAKYEAEISEL 2712
Query: 110 TPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTP---NSDVHYSIVSG 166
P T V +T D F D N+ + Y +
Sbjct: 2713 APLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAK 2772
Query: 167 NDDGHF-ALESSH-KPVLLLR--KVLDYDAGDKE--FQLV----IMASGKRIHKEILFPE 216
+ + A +S H +P+ L+ ++ +D D E F L +A + + +
Sbjct: 2773 SYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVF--- 2829
Query: 217 PIHAIDQDLGVGATLRYEL----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
HA D D G L Y + + K+F +DS +G + D + Q +
Sbjct: 2830 RAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYE-----QRQRY 2884
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI--VENLPNGFSVLQVMA 330
+++ AS + + RVEIE D + P+F Y + LP G+ V QV A
Sbjct: 2885 DMELLASDMGGKKASVAVRVEIESRD--EFTPQFTERTYRFVLPAAVALPQGYVVGQVTA 2942
Query: 331 TDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
TD D G +G YQL P F ++ SG + ++ + LD + +L M
Sbjct: 2943 TDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLYM 2991
Score = 62.9 bits (146), Expect = 7e-08
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 25/190 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A+D+D G A++ Y ++ G D LFS+D +G + + LD E + + + L
Sbjct: 1226 VRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSG--VIRTRVVLDHE---ERSIYRL 1280
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK- 333
V AS NP + + +E+LDLNDN P F + E+ G V + ++
Sbjct: 1281 GVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERP 1340
Query: 334 ---------DQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
+ E+ TY L D + AF ID SG L V +LDRE S R+
Sbjct: 1341 ADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVAR--LLDREVQSEFRL 1398
Query: 380 KVYAKETNPS 389
++ A +T S
Sbjct: 1399 EIRALDTTAS 1408
Score = 60.1 bits (139), Expect = 5e-07
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 4/132 (3%)
Query: 1024 NLNDNISVRVFVKDVNDHFPVF-KKTWYNFNVEEAQYTRRVLGKVDATDADFGQ--NANL 1080
N + ISV + + D ND+FP+F + Y + E R + ++ A DAD N+ +
Sbjct: 2678 NSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEV 2737
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK-YILTVVARDNGXXXXXXXXXXXXX 1139
Y I + + F I +TGVL VN LD ++ K Y L + A D+
Sbjct: 2738 VYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRL 2797
Query: 1140 XXXDVNDNSPKF 1151
D NDN PKF
Sbjct: 2798 ELHDENDNEPKF 2809
Score = 57.2 bits (132), Expect = 3e-06
Identities = 56/239 (23%), Positives = 104/239 (43%), Gaps = 17/239 (7%)
Query: 153 NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI 212
N+ +++ +V+ D F L S + V+ L + D K Q +A+ + +
Sbjct: 2229 NSQPNEIRVVLVARTADAPF-LASYAELVIELED--ENDNSPKFSQKQFVATVSEGNNKG 2285
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
F +HA D D G A LRY ++ GN F ++ + + + LD E + +
Sbjct: 2286 TFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGI-VRTNIVLDREIR---DIY 2341
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L++ A+ P T A + ++++D+NDN P F + +++ E G + + A D
Sbjct: 2342 KLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISAND 2400
Query: 333 KDQGE------NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D E T +++ F++D SG L ++ + LD E + V A +
Sbjct: 2401 VDTYPALTYRLGAESTVDIEN-MSIFALDRYSGKLVLKRR--LDYELQQEYELDVIASD 2456
Score = 52.4 bits (120), Expect = 9e-05
Identities = 46/153 (30%), Positives = 70/153 (45%), Gaps = 25/153 (16%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHY 1285
G P L + +T+ DV D ++P+F Y + EN V V V + T+
Sbjct: 209 GTPPLRGFMTVNITIQDVND-----NQPIFNQSRYFATVPENATVGTSVLQVYASDTDAD 263
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
EN + Y I N +D + F IDPR G +Y+ ++ D E K+ +E++V
Sbjct: 264 ENGLVEYAI-NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVV------------ 310
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
VA+D E + V +R+ DVNDN P
Sbjct: 311 -----VAKDHGEQPLETTAFVSIRVTDVNDNQP 338
Score = 52.0 bits (119), Expect = 1e-04
Identities = 72/307 (23%), Positives = 127/307 (41%), Gaps = 23/307 (7%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVP 135
Q AY ++ I ++++++ + D D + I++I P ++ P
Sbjct: 2483 QPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVH---P 2539
Query: 136 RGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
+ ++ R +P +S ++ + D G AL+SS LL + D +G
Sbjct: 2540 SNGVVSVNM---SRLQPAVSSSGDYFVRIIAKDAGKPALKSS---TLLRVQANDNGSGRS 2593
Query: 196 EFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLR-YELISGNDRKLFSLDSVNGSLF 254
+F + +I P+ ++ LG A + +I+GN+ F L + ++
Sbjct: 2594 QFLQ------NQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQ-SKAIV 2646
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA-RVEIELLDLNDNLPEFEVDF-YN 312
L K LD + + + L + L ++ V I +LD NDN P F+ Y
Sbjct: 2647 LVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYE 2706
Query: 313 ISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
I E P +S+ Q+ A D DQ N E Y + + + F+ID +G L V N+
Sbjct: 2707 AEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLD 2766
Query: 369 LDREAHS 375
D A S
Sbjct: 2767 YDSGAKS 2773
Score = 40.7 bits (91), Expect = 0.30
Identities = 19/49 (38%), Positives = 28/49 (57%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVFGF 1489
A D+D+G+NA + Y + NE +FAID SG + V L R+ + F
Sbjct: 1923 AVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNF 1971
>UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep:
Cadherin - Aedes aegypti (Yellowfever mosquito)
Length = 3131
Score = 191 bits (466), Expect = 1e-46
Identities = 215/761 (28%), Positives = 330/761 (43%), Gaps = 107/761 (14%)
Query: 219 HAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+A D+D G+ + Y L + LFS+DS +G L L + LD + +Q +T + V
Sbjct: 581 NAHDKDSGMSGVITYRLSNNGPATGNLFSIDSRSGHLSLARPLDYET---VQRHTLI--V 635
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS P + + +E+ D+NDN P FE Y I + E+ P+ ++QV A D D G
Sbjct: 636 TASDSGIPSLSTNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTG 695
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFA 395
N TY++ D R+ R SS + A E N P + G F
Sbjct: 696 NNARLTYRI------LGDDQRT------------RTGKSSSK----ASEANTPEIFGIFP 733
Query: 396 DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDN 455
+S I + E T V + V T T +V V++LDANDN
Sbjct: 734 NSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTAT-----------THVIVSVLDANDN 782
Query: 456 NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
NP+F LYEF ++ N + G+VIG + A D D G N +V Y L + + F+INP
Sbjct: 783 NPIFA-KQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSL-----IPSNTSFQINP 836
Query: 516 NTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
+G ++ + E + + L VEA DQ R S+ + ++V N P+I D
Sbjct: 837 ISGEITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDV----NDNSPEIVD- 891
Query: 574 MGAPYE--FWVGSNVGIGTSVGQIRVNDA-FEQN-DVSYDLLHGYEEG--VPFAVEERSG 627
P E V IGT V ++R D + N ++Y +L G + F ++ +G
Sbjct: 892 ---PQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHGMFTIDPITG 948
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPII 685
+I L + +Y AVA +N V + V+D+ND R S ++
Sbjct: 949 LIRTKASLDHEEKTIYRL-AVAATDNGKPPRQTVRLLRIEVLDLNDNRPTF---TSSSLV 1004
Query: 686 FHVKEN-SAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIA------EDGT 737
F ++E+ G IG I S + T N + +T+DIA G
Sbjct: 1005 FRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDRNSGK 1064
Query: 738 IFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ + LDRE++ YRM + A + + + V I I D NDNPP + +I
Sbjct: 1065 LVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYI 1124
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG---KEMFDVDENTGVVKFIGDSL 853
E++ +G+ + ATD D GTNA Y + KE F +D TG + + L
Sbjct: 1125 SEDAAVGSVVFN---FTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGSLTLLA-PL 1180
Query: 854 DREKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEF-------------NQ 895
D E+ + L + A D T +++ A IM+ D NDN P+F +
Sbjct: 1181 DYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDTTVYVSDS 1240
Query: 896 IEEN----SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVD 932
+E N V I R++ NG + I+ +FA+D D
Sbjct: 1241 MEVNHIVSHVVAIDRDSGENGRVVYKIVSGNEDERFAIDPD 1281
Score = 164 bits (399), Expect = 1e-38
Identities = 141/499 (28%), Positives = 238/499 (47%), Gaps = 54/499 (10%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSM--KSNAKVGTVIGKVKAVD 486
T+ E++ + + + D NDN+P FV + ++ + +V ++ V A+D
Sbjct: 1195 TDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAID 1254
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE-----------SPILEGRHALF 535
D G+NG V+Y + + F I+P+TG V +A+ + GR+ L
Sbjct: 1255 RDSGENGRVVYKIVSGNE---DERFAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLV 1311
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
+ A+DQ S+ A +TI+V N P P F+ + Y + NV G+ V +
Sbjct: 1312 ITATDQGTPRSKE----AKITIQVVIQNTSNNP--PRFLESVYHINITENVPTGSFV--V 1363
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYD-------- 644
RV+ ++ + +L + +GV F V+ G++T R ++ MY
Sbjct: 1364 RVSAKSYNDNGNANLTYEIPKGVGDDHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQ 1423
Query: 645 --FEAVALQENANLSIVTNAT--VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
F++ A + ++S AT V + DVND L G+ P+ V ENS + I
Sbjct: 1424 NRFKSAASGTSKDMSQFDVATLVVRITDVNDHAPEFLPGSCYPLA--VPENSELSVI--- 1478
Query: 701 FHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
HT ++S G G + + I+ ++ + +I + T +PLDRE Y + + A+
Sbjct: 1479 -HTVVASDADEGLNGEITYSISGG-NIGNKFSIDMNTGALTARPLDREIHARYVLQITAQ 1536
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
S G +T+ +EDENDN P FE Y I E++ IGT + +KA DAD
Sbjct: 1537 DRGSPTSHQGHCNITVRVEDENDNDPKFELQKYIATIDEDAPIGTTVL---TVKAVDADI 1593
Query: 820 GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAEL 879
G NA +Y+L + +FD+D +GV+ G DRE++ +Y +VA D G ++ ++
Sbjct: 1594 GINARIVYSLANVTEWLFDIDSKSGVITTAG-HFDRERQSIYNFMVVATDGGRYNARSQS 1652
Query: 880 I---IMIGDENDNKPEFNQ 895
+ ++I D NDNKP F++
Sbjct: 1653 VQVQVIIADVNDNKPVFDK 1671
Score = 152 bits (369), Expect = 6e-35
Identities = 198/739 (26%), Positives = 314/739 (42%), Gaps = 85/739 (11%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV--GTVIGKVKAVDPDLGQNGMVLYDLQ 500
V V+V + D NDN PVF + Y F + A V G + + A D D G NG ++Y L
Sbjct: 1653 VQVQVIIADVNDNKPVF---DKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLN 1709
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQP-ANPSERRYSLAVVTIEV 559
N + F+INPNTG +S +S E L +E + + NP + +A IE+
Sbjct: 1710 DNPN---NAKFRINPNTGALSATQSLASENGRLLHIEVTARDKGNPPQ----VATGLIEL 1762
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR-VNDAFEQNDVSYDLLHGYEEGV 618
G + F Y+ + N IG +V + V + + Y G E+G
Sbjct: 1763 RVGDLQQELPALKFQNNSYKVNLVENTPIGQTVLHLNAVRSDGRRQKIIYSFGSGNEDGT 1822
Query: 619 PFAVEERSGVITV-------VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DV 669
F+++ +G + + + SR N D AVA + + L + ++ VV D
Sbjct: 1823 -FSIDAVTGEVKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPL-LYGYCSIKVVLQDE 1880
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND + +S ++ + N+ G + ++ + G+ + ++ D
Sbjct: 1881 NDNAPRFTQQQYSASVW--EGNNKGEFVIKV--NAFDTDQGSNAHILYHIVDGNHDNAFI 1936
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I A G + T LDRE RD Y++ VIA ++GV G + + + D NDN P F
Sbjct: 1937 IEPAFSGIVKTNIVLDREIRDKYKLKVIAT-DEGVPQMTGTATINVNVVDVNDNQPTFPP 1995
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDENTG 844
+ + E + +GT + I A D D TN Y+ FG+ K F +D +G
Sbjct: 1996 NSVIS-VSEATTVGTVLTS---ITANDVD--TNPPLTYS-FGDSPDEDAKSYFSIDRYSG 2048
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
V I LD E + ++L ++A D+ ++ L + + D NDN P+F QI ++
Sbjct: 2049 KVILI-KPLDYEARHEFQLRILASDSAHVARTL-LTVRVTDVNDNPPQFQQITYHA---- 2102
Query: 905 HRETKLNGT--AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
LNGT F F+L D NI II +NA D DS
Sbjct: 2103 ----MLNGTNFPRFKNPGTHSNISFSLITDDTDS----NSNI----AIIAVNATDSDSEN 2150
Query: 963 NGQIRYEFNSEVYIPPS-KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALD 1021
N IRY IPPS + DAL + + +++ H RS L I+A D
Sbjct: 2151 NAAIRY-----TIIPPSIGFAIDALTGQLFVNMSQVHR----TRS----GTLYLTITATD 2197
Query: 1022 GG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV--DATDADFGQN 1077
G L+ + +VR+ +K + P F ++ Y ++ E T V+ + A +
Sbjct: 2198 SGVPPLSSSTTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQVDVS 2257
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX-----XXXX 1132
+++ + I + D FEIS +G + + LDRE D Y L +V + G
Sbjct: 2258 SSIAFEIIDGNDDNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGATMMYKGMNMS 2317
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D NDN+P+F
Sbjct: 2318 SAIRVTITVEDANDNAPEF 2336
Score = 134 bits (323), Expect = 2e-29
Identities = 233/981 (23%), Positives = 389/981 (39%), Gaps = 120/981 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP-DL-----GQNGM-VLY 497
+ + +LD NDN P F S+L F ++ + VG VIG + + DL N + + Y
Sbjct: 984 LRIEVLDLNDNRPTFTSSSLV-FRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITY 1042
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
L +N F I+ N+G + VA S E + +E + S S AV T+
Sbjct: 1043 TLTPLTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNPQSSAV-TV 1101
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH-GY 614
++ + P P + P ++ + +G+ V ND+ ++ Y++
Sbjct: 1102 KIEIADVNDNP--PKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNISKPAT 1159
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS--IVTNAT--VHVVDVN 670
+ F+++ +G +T++ L + A +++N++ + T+AT + V DVN
Sbjct: 1160 AQKEFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVN 1219
Query: 671 DERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D ++ A ++ + + + S G V +++ +D +
Sbjct: 1220 DNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDS--GENGRVVYKIVSGNED--ER 1275
Query: 730 IAIAED-GTIFTQKPL------DREKRDV---YRMTVIAEFNKGVISGAGIYQVTIYIED 779
AI D G + KP D K + Y + + A S + + I++
Sbjct: 1276 FAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQN 1335
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFD 838
++NPP F + Y I EN G+ + + A ++ NA Y + G G + F
Sbjct: 1336 TSNNPPRFLESVYHINITENVPTGSFVVR---VSAKSYNDNGNANLTYEIPKGVGDDHFV 1392
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEE 898
VD G+V G + DRE K MY + + + S A G D +Q +
Sbjct: 1393 VDSVRGIVTTRG-TFDRESKDMYTVPIYVTEQNRFKSAAS-----GTSKD----MSQFDV 1442
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDL 958
+ V R T +N A E P + + L V PEN + + I + A D
Sbjct: 1443 ATLVV--RITDVNDHAP----EFLPGSCYPLAV---------PENSEL-SVIHTVVASDA 1486
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LN 1016
D GLNG+I Y + + F I+ G + AR L E R L
Sbjct: 1487 DEGLNGEITYSISGG-------------NIGNKFSIDMNTG-ALTARPLDREIHARYVLQ 1532
Query: 1017 ISALDGGNLNDN---ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
I+A D G+ + ++ V V+D ND+ P F+ Y ++E + V A DAD
Sbjct: 1533 ITAQDRGSPTSHQGHCNITVRVEDENDNDPKFELQKYIATIDEDAPIGTTVLTVKAVDAD 1592
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
G NA + Y + + T+ F+I +GV++ G DRE + Y VVA D G
Sbjct: 1593 IGINARIVYSLA-NVTEWLFDIDSKSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQ 1651
Query: 1134 XXXXXXXXXDVNDNSPKF--YAFDE-----------LLEWKHPEADELSNHNFESVMMIP 1180
DVNDN P F Y F E LL + D+ SN +
Sbjct: 1652 SVQVQVIIADVNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDN 1711
Query: 1181 VYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMV 1240
A N G A T + + NG +L+ +++ N P +T ++ +
Sbjct: 1712 PNNAKFRINPNTGALSA------TQSLASENGRLLHIEVTARDKGN---PPQVATGLIEL 1762
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDT 1300
V D+ E+ F + Y++ + EN ++ LN + Y +
Sbjct: 1763 RVGDLQQELPALK---FQNNSYKVNLVENTPIGQTVLHLNAVRSDGRRQKIIYSFGSGNE 1819
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
D TF ID G + + S + + YE R + +L + +L G
Sbjct: 1820 D--GTFSIDAVTGEVKIRNSHNLD----YERFSRLNTE--GIDLVAVARTDGSPLLYGYC 1871
Query: 1361 KYDVKVVVRIKDVNDNSPKFT 1381
+KVV ++D NDN+P+FT
Sbjct: 1872 --SIKVV--LQDENDNAPRFT 1888
Score = 118 bits (285), Expect = 9e-25
Identities = 134/496 (27%), Positives = 205/496 (41%), Gaps = 65/496 (13%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYI 976
++EV+ N A ++ + E+ P + I+++ A+D D+G N ++ Y +
Sbjct: 652 LVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILGDDQRT 711
Query: 977 PPSKLSADALEVK--RYFVINERHGHVIVARSLPPESEFRLNISAL--DGG--NLNDNIS 1030
K S+ A E F I G + + L E + R NI+ + D G L
Sbjct: 712 RTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTATTH 771
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V D ND+ P+F K Y F +EE V+G + ATDAD G NA + Y + PS+T
Sbjct: 772 VIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLIPSNTS 831
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F+I+P++G ++ LDRET+ Y L V ARD G DVNDNSP
Sbjct: 832 --FQINPISGEITTRDRLDRETKSIYDLVVEARDQG-TPYRSSRVSIKIKILDVNDNSP- 887
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
E+++ P+ D +S + + V I+ + + ++ D G+G
Sbjct: 888 -----EIVD---PQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHG 939
Query: 1211 -------NGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSD 1253
GLI ++ + G P + +L + V D+ D +
Sbjct: 940 MFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLND-----N 994
Query: 1254 KPVFISRYYELEIEENVNA--PVELVSLNLTEHYENFKMR------YYILNENDTDIRR- 1304
+P F S + E+V + +S N EN Y L DI
Sbjct: 995 RPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEG 1054
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
F ID +G L + RS DRE + Y + +RA S P + V
Sbjct: 1055 AFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNN------PQSS---------AV 1099
Query: 1365 KVVVRIKDVNDNSPKF 1380
V + I DVNDN PK+
Sbjct: 1100 TVKIEIADVNDNPPKW 1115
Score = 117 bits (282), Expect = 2e-24
Identities = 126/494 (25%), Positives = 212/494 (42%), Gaps = 59/494 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNL---YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V++ L D NDN P F P SM +N+ + T + + A D D G G + Y +
Sbjct: 329 VKIQLTDVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVATDSDSGSFGTISYRIVA 388
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVTI 557
+ I F+++ TG + VA +L R H L + ASD S + + I
Sbjct: 389 GNEAGI---FRMDRLTGEIFVARPNMLSSRSQPYHRLNISASDGGGLRSTHDAEVFISVI 445
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYE 615
+ T+ +P P F Y ++V +V T VG + +++ + + Y + G
Sbjct: 446 DATQ-----RP--PIFDKPRYTYYVKEDVKKNTVVGTVSATSSNSGSRGSIRYFIYSGDP 498
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+G FA++ SG I V L +P A + T + + DVND
Sbjct: 499 DGY-FAIDPVSGNIRVASTLDHETKPQVLLNIQATSGDPPAYGHTQVNIDIEDVNDNPPE 557
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
S + V EN IG ++ N +G + + ++N T ++ +
Sbjct: 558 F---ESSTVRISVPEN---VEIGSPLYAANAHDKDSGMSGVITYRLSNNGPATGNLFSID 611
Query: 735 D--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + +PLD E + + V A + G+ S + + + ++D NDN PVFE + Y
Sbjct: 612 SRSGHLSLARPLDYETVQRHTLIVTAS-DSGIPSLSTNLTILVEVQDVNDNAPVFERSEY 670
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------GK-----------E 835
+ E++ ++I + A DAD G NA Y + G+ GK E
Sbjct: 671 AIKVSESTPSNSQIMQ---VTAVDADTGNNARLTYRILGDDQRTRTGKSSSKASEANTPE 727
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+F + N+G + ++ LDRE + Y ++++ D G L++ +I+ + D NDN P F
Sbjct: 728 IFGIFPNSGWI-YLRTKLDREDQERYNITVIVSDNGVPTLTATTHVIVSVLDANDNNPIF 786
Query: 894 N------QIEENSK 901
QIEEN +
Sbjct: 787 AKQLYEFQIEENMR 800
Score = 117 bits (281), Expect = 3e-24
Identities = 126/486 (25%), Positives = 205/486 (42%), Gaps = 50/486 (10%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D V + + D NDN P F S+ S+ N ++G+ + A D D G +G++
Sbjct: 535 DPPAYGHTQVNIDIEDVNDNPPEF-ESSTVRISVPENVEIGSPLYAANAHDKDSGMSGVI 593
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
Y L T + F I+ +G +S+A E RH L V ASD ++
Sbjct: 594 TYRLSNNGPAT-GNLFSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLSTNLTIL 652
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V +V + P F + Y V + + + Q+ DA N+ ++Y +L
Sbjct: 653 VEVQDV-------NDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRIL 705
Query: 612 -------------HGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-N 655
E P F + SG I + L R ++ Y+ +
Sbjct: 706 GDDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPT 765
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTG 714
L+ T+ V V+D ND + K + F ++EN G+ IG I T+ + N
Sbjct: 766 LTATTHVIVSVLDANDNNPIFAKQLYE---FQIEENMRRGSVIGLITATDADAGI-NAVV 821
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ +N + I+ G I T+ LDRE + +Y + V A ++G + +
Sbjct: 822 RYSLIPSNTSFQINPIS----GEITTRDRLDRETKSIYDLVVEAR-DQGTPYRSSRVSIK 876
Query: 775 IYIEDENDN-PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF--- 830
I I D NDN P + + + E IGTE+ ++A D D G NA Y++
Sbjct: 877 IKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVR---VRAIDRDYGVNASITYSILKGR 933
Query: 831 -GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DEN 887
+G MF +D TG+++ SLD E+K +Y+L++ A D G + ++ I D N
Sbjct: 934 DSDGHGMFTIDPITGLIR-TKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLN 992
Query: 888 DNKPEF 893
DN+P F
Sbjct: 993 DNRPTF 998
Score = 105 bits (252), Expect = 9e-21
Identities = 119/484 (24%), Positives = 207/484 (42%), Gaps = 42/484 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V++++ +LD NDN+P V S++ +GT + +V+A+D D G N + Y +
Sbjct: 871 SRVSIKIKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSIL 930
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
+ + F I+P TG + S E + + L V A+D P R ++ ++ IE
Sbjct: 931 KGRDSDGHGMFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPP---RQTVRLLRIE 987
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-------QND--VSY- 608
V N+ P F + F + +VG+G +G I N+ + ND ++Y
Sbjct: 988 VL-DLNDNR---PTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYT 1043
Query: 609 --DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
L + EG F ++ SG + V L R + Y E AL +A+ + ++A
Sbjct: 1044 LTPLTNDIAEGA-FDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVK 1102
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQD 725
+++ D K P+ ++ E+ AA+G + ++ +GT +++ I+
Sbjct: 1103 IEIADVNDNPPKWPSDPMNVYISED---AAVGSVVFNFTATDNDSGTNAEIKYNISKPAT 1159
Query: 726 VTDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT--IYIEDEN 781
+ + G++ PLD E+ + + V A ++ T I + D N
Sbjct: 1160 AQKEFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVN 1219
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD 840
DN P F + + S + + + A D D G N +Y + G E F +D
Sbjct: 1220 DNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIVSGNEDERFAID 1279
Query: 841 ENTGVVK--------FIGDSLDREKKIMYKLSLVARDTG-GLSSEAELIIMIGDEN--DN 889
+TG VK FI D+ Y L + A D G S EA++ I + +N +N
Sbjct: 1280 PDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQNTSNN 1339
Query: 890 KPEF 893
P F
Sbjct: 1340 PPRF 1343
Score = 100 bits (239), Expect = 4e-19
Identities = 126/480 (26%), Positives = 201/480 (41%), Gaps = 52/480 (10%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F + E++ +G I ++ + S L I + + + L+ D E F I+
Sbjct: 1004 VFRLREDVGVGHVIGSISGNE-QSDLENLITSSNDLHITYTLTPLTNDIAEGA--FDIDR 1060
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGNLNDN----ISVRVFVKDVNDHFPVFKKTWY 1050
G ++VARSL E SE+R+ I ALD N+ ++V++ + DVND+ P +
Sbjct: 1061 NSGKLVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPM 1120
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGEL 1108
N + E V+ ATD D G NA + Y I T F I LTG L++ L
Sbjct: 1121 NVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGSLTLLAPL 1180
Query: 1109 DRETEDKYILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
D E +++L V A D + DVNDNSPKF + + +D
Sbjct: 1181 DYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKF-VVPQAQDTTVYVSD 1239
Query: 1167 ELS-NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGNGLILYSLPQRK 1222
+ NH V+ I ++ G V K+ + + D I G + + P
Sbjct: 1240 SMEVNHIVSHVVAID------RDSGENGRVVYKIVSGNEDERFAIDPDTGFVKLAKPFSS 1293
Query: 1223 N-QQNLGLPSLSSTAILMVTVAD--VPDEVE------------MSDKPVFISRYYELEIE 1267
N + S++ L++T D P E ++ P F+ Y + I
Sbjct: 1294 NFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQNTSNNPPRFLESVYHINIT 1353
Query: 1268 ENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
ENV +V ++ + + N + Y I D FV+D G + + DRE
Sbjct: 1354 ENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGDD---HFVVDSVRGIVTTRGTFDRES 1410
Query: 1326 KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV-KVVVRIKDVNDNSPKFTNGN 1384
KD Y V + Q + A + M+++DV +VVRI DVND++P+F G+
Sbjct: 1411 KDMYTVPIYVTEQNRFKS-------AASGTSKDMSQFDVATLVVRITDVNDHAPEFLPGS 1463
Score = 98.3 bits (234), Expect = 1e-18
Identities = 109/421 (25%), Positives = 176/421 (41%), Gaps = 47/421 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+P N + T ++ + A D DSG G I Y + ++ E+ FV
Sbjct: 356 MPTNSLLSTPVVVIVATDSDSGSFGTISYRIVAGNEAGIFRMDRLTGEI---FVARP--- 409
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEA 1057
+++ +RS P RLNISA DGG L VF+ D P+F K Y + V+E
Sbjct: 410 NMLSSRSQP---YHRLNISASDGGGLRSTHDAEVFISVIDATQRPPIFDKPRYTYYVKED 466
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
V+G V AT ++ G ++ YFI D D F I P++G + V LD ET+ + +
Sbjct: 467 VKKNTVVGTVSATSSNSGSRGSIRYFIYSGDPDGYFAIDPVSGNIRVASTLDHETKPQVL 526
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL------SNH 1171
L + A DVNDN P+F + + PE E+ +N
Sbjct: 527 LNIQA--TSGDPPAYGHTQVNIDIEDVNDNPPEFES--STVRISVPENVEIGSPLYAANA 582
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK----NQQNL 1227
+ + M V + N P + + + + + L Y QR +
Sbjct: 583 HDKDSGMSGVITYRLSNNGPATGNLFSIDSR-SGHLSLARPLD-YETVQRHTLIVTASDS 640
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHY 1285
G+PSLS+ ++V V DV D + PVF Y +++ E+ N+ + V+ +
Sbjct: 641 GIPSLSTNLTILVEVQDVND-----NAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTG 695
Query: 1286 ENFKMRYYILNE-------------NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
N ++ Y IL + ++ + F I P +G +YL DRE ++ Y +
Sbjct: 696 NNARLTYRILGDDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNIT 755
Query: 1333 V 1333
V
Sbjct: 756 V 756
Score = 98.3 bits (234), Expect = 1e-18
Identities = 113/464 (24%), Positives = 193/464 (41%), Gaps = 33/464 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+ V + D NDN+P F Y ++ +A +GT + VKAVD D+G N ++Y L +
Sbjct: 1549 NITVRVEDENDNDPKFELQK-YIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANVT 1607
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLAVVTIEVTRG 562
F I+ +G ++ A E + F+ + + R S+ V I
Sbjct: 1608 EWL----FDIDSKSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSVQVQVI--IAD 1661
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
NKP + P++ +G+ V G ++ I D + ++ Y L + F
Sbjct: 1662 VNDNKPVFDKY---PFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSL-NDNPNNAKF 1717
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT-VHVVDVNDERGVLLKG 679
+ +G ++ L+ N + E A + + T + V D+ E L K
Sbjct: 1718 RINPNTGALSATQSLASENGRLLHIEVTARDKGNPPQVATGLIELRVGDLQQELPAL-KF 1776
Query: 680 AHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AIAEDGT 737
++ ++ EN+ IGQ + H N G + + +D T I A+ +
Sbjct: 1777 QNNSYKVNLVENTP---IGQTVLHLNAVRSDGRRQKIIYSFGSGNEDGTFSIDAVTGEVK 1833
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGA----GIYQVTIYIEDENDNPPVFEHATYE 793
I LD E+ I G+ G + + ++DENDN P F Y
Sbjct: 1834 IRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKVVLQDENDNAPRFTQQQYS 1893
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDEN-TGVVKFIGD 851
+ E + G + + A D D+G+NA +Y + G F ++ +G+VK
Sbjct: 1894 ASVWEGNNKGEFVIK---VNAFDTDQGSNAHILYHIVDGNHDNAFIIEPAFSGIVK-TNI 1949
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
LDRE + YKL ++A D G ++ A + + + D NDN+P F
Sbjct: 1950 VLDREIRDKYKLKVIATDEGVPQMTGTATINVNVVDVNDNQPTF 1993
Score = 97.9 bits (233), Expect = 2e-18
Identities = 120/437 (27%), Positives = 192/437 (43%), Gaps = 39/437 (8%)
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQ 541
V A DPD G N MV Y L IT F+I +TG V +A E R++ +
Sbjct: 261 VSATDPDCGVNAMVNYTLGEGYK-KITE-FEIRSSTGEVCIAAELDYETRNSY-----EF 313
Query: 542 PANPSERR--YSLAVVTIEVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVN 598
P ++R + A+V I++T N+P P + +N + T V I
Sbjct: 314 PIIATDRGGLSTTAMVKIQLT-DVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVAT 372
Query: 599 DAFEQN--DVSYDLLHGYEEGVPFAVEERSGVITVV--DDLSRYNRPMYDFEAVALQENA 654
D+ + +SY ++ G E G+ F ++ +G I V + LS ++P + ++ +
Sbjct: 373 DSDSGSFGTISYRIVAGNEAGI-FRMDRLTGEIFVARPNMLSSRSQPYHRLN-ISASDGG 430
Query: 655 NLSIVTNATVH--VVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGN 711
L +A V V+D + K ++ ++VKE+ +G + T+ +S
Sbjct: 431 GLRSTHDAEVFISVIDATQRPPIFDKPRYT---YYVKEDVKKNTVVGTVSATSSNS---G 484
Query: 712 GTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
G++R+ I + D AI G I LD E + + + A G G
Sbjct: 485 SRGSIRYFIYSG-DPDGYFAIDPVSGNIRVASTLDHETKPQVLLNIQA--TSGDPPAYGH 541
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
QV I IED NDNPP FE +T + EN +IG+ + N A D D G + + Y L
Sbjct: 542 TQVNIDIEDVNDNPPEFESSTVRISVPENVEIGSPLYAAN---AHDKDSGMSGVITYRLS 598
Query: 831 GEGK---EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
G +F +D +G + + LD E + L + A D+G LS+ +++ + D
Sbjct: 599 NNGPATGNLFSIDSRSGHLS-LARPLDYETVQRHTLIVTASDSGIPSLSTNLTILVEVQD 657
Query: 886 ENDNKPEFNQIEENSKV 902
NDN P F + E KV
Sbjct: 658 VNDNAPVFERSEYAIKV 674
Score = 95.1 bits (226), Expect = 1e-17
Identities = 122/477 (25%), Positives = 206/477 (43%), Gaps = 48/477 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D ND+ P F+P + Y ++ N+++ +VI V A D D G NG + Y + S
Sbjct: 1447 VRITDVNDHAPEFLPGSCYPLAVPENSEL-SVIHTVVASDADEGLNGEITYSI---SGGN 1502
Query: 507 ITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
I + F I+ NTG ++ + R+ L + A D+ + S + + V +E
Sbjct: 1503 IGNKFSIDMNTGALTARPLDREIHARYVLQITAQDRGSPTSHQGHCNITVRVE-----DE 1557
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVE 623
N D P F Y + + IGT+V ++ DA + + Y L + E F ++
Sbjct: 1558 NDND-PKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANVTEW--LFDID 1614
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVAL---QENANLSIVTNATVHVVDVNDERGVLLKGA 680
+SGVIT R + +Y+F VA + NA V V + DVND + V K
Sbjct: 1615 SKSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSV-QVQVIIADVNDNKPVFDK-- 1671
Query: 681 HSPIIFHVKENSAGAAI--GQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ KE GA + GQ + H + + + G + + + + + G
Sbjct: 1672 -----YPFKEQ-IGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINPNTGA 1725
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV--FEHATYEGF 795
+ + L E + + V A +KG + + + D P F++ +Y+
Sbjct: 1726 LSATQSLASENGRLLHIEVTAR-DKGNPPQVATGLIELRVGDLQQELPALKFQNNSYKVN 1784
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGD-S 852
++EN+ IG + N +++ +G +Y+ FG G E F +D TG VK +
Sbjct: 1785 LVENTPIGQTVLHLNAVRS----DGRRQKIIYS-FGSGNEDGTFSIDAVTGEVKIRNSHN 1839
Query: 853 LDREKKIMYK-----LSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
LD E+ L VAR G L + +++ DENDN P F Q + ++ V
Sbjct: 1840 LDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKVVLQDENDNAPRFTQQQYSASV 1896
Score = 93.9 bits (223), Expect = 3e-17
Identities = 110/449 (24%), Positives = 179/449 (39%), Gaps = 46/449 (10%)
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG 530
SN+ + + V A D D N + Y + + + F I+ TG + V S +
Sbjct: 2132 SNSNIAIIA--VNATDSDSENNAAIRYTI-----IPPSIGFAIDALTGQLFVNMSQVHRT 2184
Query: 531 RHA---LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG 587
R L + A+D P S V +E+ +K N P F+ + Y + +
Sbjct: 2185 RSGTLYLTITATDSGVPPLS---SSTTVRLEMKSKSKAN----PHFIQSQYRLSINEDAP 2237
Query: 588 IGTSVGQIRVNDAFEQNDVS----YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMY 643
G+ + + EQ DVS ++++ G ++ F + SG I +V L R Y
Sbjct: 2238 TGSVITNLIPKAIAEQVDVSSSIAFEIIDGNDDNC-FEISYPSGAILLVKSLDREKTDYY 2296
Query: 644 DFEAVALQENA-------NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
+ V + A N+S T+ V D ND G + I +
Sbjct: 2297 ELRLVVTEPGATMMYKGMNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKY--S 2354
Query: 697 IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV 756
IGQI + + + V +++ I + G ++ LD ++ V
Sbjct: 2355 IGQISAVDADLLNSPNSEVVYQIVSGNDGGWFSIDLIT-GLLYINNNLDYDRGPTQFNLV 2413
Query: 757 IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATD 816
I + V+ ++ I + DENDN P F Y F+ EN IG I +ATD
Sbjct: 2414 IRACDSHVLPKCSVHPFVINLTDENDNEPQFPVPEYLEFVGENEPIGISI---FTARATD 2470
Query: 817 ADEG---------TNALFM-YTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
D G NA+ Y+ +G ++F VD +GV+ D E+K Y +L
Sbjct: 2471 MDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGVIN-SNAVFDYEEKNRYSFTLR 2529
Query: 867 ARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
A DTGG S ++ IMI ++ P+F +
Sbjct: 2530 ATDTGGKSKTVKVRIMIESRDEFSPQFTE 2558
Score = 89.4 bits (212), Expect = 7e-16
Identities = 93/339 (27%), Positives = 138/339 (40%), Gaps = 21/339 (6%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTI 130
G N S + V V I DVNDN P+F P+ + L G+ +
Sbjct: 1643 GGRYNARSQSVQVQVIIADVNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNG 1702
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDG-HFALESSHK--PVLLLRKV 187
+ L + F R PNT S+ S N H + + K P + +
Sbjct: 1703 EIVY--SLNDNPNNAKF-RINPNTGALSATQSLASENGRLLHIEVTARDKGNPPQVATGL 1759
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPE-PI-------HAIDQDLGVGATLRYELISGN 239
++ GD + +L + +K L PI +A+ D G + Y SGN
Sbjct: 1760 IELRVGDLQQELPALKFQNNSYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGSGN 1818
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANT--FVLQVQASQLNNPLKTAQARVEIELL 297
+ FS+D+V G + + +LD E + NT L A +PL +++ L
Sbjct: 1819 EDGTFSIDAVTGEVKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKVVLQ 1878
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK--GAFSID 355
D NDN P F Y+ S+ E G V++V A D DQG N Y + D AF I+
Sbjct: 1879 DENDNAPRFTQQQYSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHIVDGNHDNAFIIE 1938
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
P + V+ VLDRE ++KV A + P + GT
Sbjct: 1939 PAFSGI-VKTNIVLDREIRDKYKLKVIATDEGVPQMTGT 1976
Score = 83.8 bits (198), Expect = 3e-14
Identities = 56/175 (32%), Positives = 90/175 (51%), Gaps = 17/175 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G+ A +RY LI N F ++ ++G + LD + + + + L V+
Sbjct: 808 ITATDADAGINAVVRYSLIPSNTS--FQINPISGEITTRDRLDRETK-----SIYDLVVE 860
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN--ISIVENLPNGFSVLQVMATDKDQ 335
A P ++++ ++I++LD+NDN PE VD +S+ E P G V++V A D+D
Sbjct: 861 ARDQGTPYRSSRVSIKIKILDVNDNSPEI-VDPQEDVVSVREEQPIGTEVVRVRAIDRDY 919
Query: 336 GENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G N TY + D G F+IDP +G +R + LD E + R+ V A +
Sbjct: 920 GVNASITYSILKGRDSDGHGMFTIDPITG--LIRTKASLDHEEKTIYRLAVAATD 972
Score = 83.0 bits (196), Expect = 6e-14
Identities = 109/401 (27%), Positives = 175/401 (43%), Gaps = 48/401 (11%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE---KAFIFLIAP---IGPSLTI 130
+S V + + DVNDN P F Y+V++ E PT + ++A G TI
Sbjct: 323 LSTTAMVKIQLTDVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVATDSDSGSFGTI 382
Query: 131 PLTVPRG--LTIFKDIRAFDR---DKPNTPNS---DVHYSIVSGNDDGHFALESSHKPVL 182
+ G IF+ R +PN +S H +S +D G L S+H +
Sbjct: 383 SYRIVAGNEAGIFRMDRLTGEIFVARPNMLSSRSQPYHRLNISASDGG--GLRSTHDAEV 440
Query: 183 LLRKVLDYDAGDKEFQLVIMASG-KRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
+ V+D F K K+ + A + G ++RY + SG+
Sbjct: 441 FI-SVIDATQRPPIFDKPRYTYYVKEDVKKNTVVGTVSATSSNSGSRGSIRYFIYSGDPD 499
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F++D V+G++ + LD + + + +L +QA+ +P +V I++ D+ND
Sbjct: 500 GYFAIDPVSGNIRVASTLDHETKPQV-----LLNIQATS-GDPPAYGHTQVNIDIEDVND 553
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPR 357
N PEFE IS+ EN+ G + A DKD G +G TY+L + A FSID R
Sbjct: 554 NPPEFESSTVRISVPENVEIGSPLYAANAHDKDSGMSGVITYRLSNNGPATGNLFSIDSR 613
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQPLETNAPL-E 415
SG L++ LD E + V A ++ PS+ + Q + NAP+ E
Sbjct: 614 SGHLSLARP--LDYETVQRHTLIVTASDSGIPSLSTNLTILVEV-----QDVNDNAPVFE 666
Query: 416 KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
++ Y KV T + + Q+M +VT +DA+ N
Sbjct: 667 RSEYAI--KVSESTPS----NSQIM-----QVTAVDADTGN 696
Score = 83.0 bits (196), Expect = 6e-14
Identities = 150/724 (20%), Positives = 267/724 (36%), Gaps = 56/724 (7%)
Query: 445 VEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+E+ + D P +N Y+ ++ N +G + + AV D G+ ++Y +
Sbjct: 1760 IELRVGDLQQELPALKFQNNSYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGSGN 1818
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEVTR 561
F I+ TG V + S L+ L E D A L +
Sbjct: 1819 E---DGTFSIDAVTGEVKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKV 1875
Query: 562 GTKGNKPDIPDFMGAPYE--FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
+ + P F Y W G+N G D + Y ++ G +
Sbjct: 1876 VLQDENDNAPRFTQQQYSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHIVDGNHDNA- 1934
Query: 620 FAVEER-SGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
F +E SG++ L R R Y + +A E ++ V+VVDVND +
Sbjct: 1935 FIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVNVVDVNDNQPTFP 1994
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DG 736
+ +I + + G + I ++ + N F + +D +I G
Sbjct: 1995 PNS---VISVSEATTVGTVLTSITANDVDT---NPPLTYSFGDSPDEDAKSYFSIDRYSG 2048
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ KPLD E R +++ ++A + V +T+ + D NDNPP F+ TY +
Sbjct: 2049 KVILIKPLDYEARHEFQLRILASDSAHVARTL----LTVRVTDVNDNPPQFQQITYHAML 2104
Query: 797 MENS-----KIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIG 850
+ GT + + D D +N A+ E T + IG
Sbjct: 2105 NGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNAAIRYTIIPPSIG 2164
Query: 851 DSLDR-EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
++D ++ +S V R G L + I + P + ++ VR+ ++K
Sbjct: 2165 FAIDALTGQLFVNMSQVHRTRSGT-----LYLTITATDSGVPP---LSSSTTVRLEMKSK 2216
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
F ++++ L +++ P + N+ I I + +D+ S + +I +
Sbjct: 2217 SKANPHFI------QSQYRLSINEDAPTGSVITNL-IPKAIAE--QVDVSSSIAFEI-ID 2266
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI 1029
N + S S L VK ++ R + E + G N++ I
Sbjct: 2267 GNDDNCFEISYPSGAILLVKS---LDREKTDYYELRLVVTEPGATMMYK---GMNMSSAI 2320
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF--GQNANLTYFIQPS 1087
V + V+D ND+ P F+ Y + E + +G++ A DAD N+ + Y I
Sbjct: 2321 RVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEVVYQIVSG 2380
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
+ F I +TG+L +N LD + V+ + D NDN
Sbjct: 2381 NDGGWFSIDLITGLLYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHPFVINLTDENDN 2440
Query: 1148 SPKF 1151
P+F
Sbjct: 2441 EPQF 2444
Score = 83.0 bits (196), Expect = 6e-14
Identities = 124/495 (25%), Positives = 197/495 (39%), Gaps = 76/495 (15%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G +IK+NA D D G N I Y + + +A +E ++ ++++ R
Sbjct: 1903 GEFVIKVNAFDTDQGSNAHILYHI-----VDGNHDNAFIIEPAFSGIVKT---NIVLDRE 1954
Query: 1007 LPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
+ +++L + A D G + ++ V V DVND+ P F +V EA VL
Sbjct: 1955 I--RDKYKLKVIATDEGVPQMTGTATINVNVVDVNDNQPTFPPNSV-ISVSEATTVGTVL 2011
Query: 1065 GKVDATDADFGQNANLTY-FIQPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ A D D N LTY F D D F I +G + + LD E ++ L ++
Sbjct: 2012 TSITANDVD--TNPPLTYSFGDSPDEDAKSYFSIDRYSGKVILIKPLDYEARHEFQLRIL 2069
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPV 1181
A D+ DVNDN P+F N S +
Sbjct: 2070 ASDSAHVARTLLTVRVT----DVNDNPPQFQQITYHAMLNGTNFPRFKNPGTHSNISF-- 2123
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY---------SLPQRKNQQNLGLPSL 1232
+ I ++ + +A + N TD N I Y ++ Q + + +
Sbjct: 2124 --SLITDDTDSNSNIAIIAVNATDSDSENNAAIRYTIIPPSIGFAIDALTGQLFVNMSQV 2181
Query: 1233 ----SSTAILMVTVAD--VPD-------EVEMSDK----PVFISRYYELEIEENV---NA 1272
S T L +T D VP +EM K P FI Y L I E+ +
Sbjct: 2182 HRTRSGTLYLTITATDSGVPPLSSSTTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSV 2241
Query: 1273 PVELVSLNLTEHYE-NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
L+ + E + + + + I++ ND + F I +G + LV+S DRE D YE+
Sbjct: 2242 ITNLIPKAIAEQVDVSSSIAFEIIDGNDDN---CFEISYPSGAILLVKSLDREKTDYYEL 2298
Query: 1332 -IVRAERQKYSRELPHMIYPVAEDVLEGMTKYD-VKVVVRIKDVNDNSPKFTNGNRPLVT 1389
+V E P A + +GM ++V + ++D NDN+P+F G P
Sbjct: 2299 RLVVTE-------------PGATMMYKGMNMSSAIRVTITVEDANDNAPEFQPG--PYEV 2343
Query: 1390 AIPTTAPFGYQVMQL 1404
AI TAP Y + Q+
Sbjct: 2344 AISETAPIKYSIGQI 2358
Score = 81.4 bits (192), Expect = 2e-13
Identities = 85/340 (25%), Positives = 141/340 (41%), Gaps = 29/340 (8%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLT 129
A N S+ ++V + I DVNDN P + P +V + E G F F G +
Sbjct: 1090 ASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAE 1149
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPN-TPNSDVHYS-------IVSGNDDGHFALESSHKPV 181
I + + T K+ + D + T + + Y IV D E
Sbjct: 1150 IKYNISKPATAQKEFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSA 1209
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIH----KEIL-FPEPIHAIDQDLGVGATLRYELI 236
V D + +F +V A ++ E+ + AID+D G + Y+++
Sbjct: 1210 TARIMVTDVNDNSPKF-VVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIV 1268
Query: 237 SGNDRKLFSLDSVNGSLFLEKELD----LDAEHNLQANTFVLQVQASQLNNPL-KTAQAR 291
SGN+ + F++D G + L K D N + L + A+ P K A+
Sbjct: 1269 SGNEDERFAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKIT 1328
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
+++ + + ++N P F Y+I+I EN+P G V++V A + N TY++ PKG
Sbjct: 1329 IQVVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEI--PKGV 1386
Query: 352 ----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
F +D G +T R DRE+ + +Y E N
Sbjct: 1387 GDDHFVVDSVRGIVTTRG--TFDRESKDMYTVPIYVTEQN 1424
Score = 81.0 bits (191), Expect = 2e-13
Identities = 88/343 (25%), Positives = 145/343 (42%), Gaps = 39/343 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G+ ++A V V + D NDN PIF Y ++E G + A G + +
Sbjct: 762 GVPTLTATTHVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVV 821
Query: 131 PLTVPRGLTIFK----DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
++ T F+ RD+ + ++ +V D G SS + + K
Sbjct: 822 RYSLIPSNTSFQINPISGEITTRDRLDRETKSIYDLVVEARDQGT-PYRSSRVSIKI--K 878
Query: 187 VLDYDAGDKEF-----QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
+LD + E +V + + I E++ + AID+D GV A++ Y ++ G D
Sbjct: 879 ILDVNDNSPEIVDPQEDVVSVREEQPIGTEVV---RVRAIDRDYGVNASITYSILKGRDS 935
Query: 242 K---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+F++D + G + + LD + + + L V A+ P + + IE+LD
Sbjct: 936 DGHGMFTIDPITGLIRTKASLDHE-----EKTIYRLAVAATDNGKPPRQTVRLLRIEVLD 990
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-------GEFTYQL-----D 346
LNDN P F + E++ G + + ++ EN TY L D
Sbjct: 991 LNDNRPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTND 1050
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+GAF ID SG L V LDRE S RM++ A +T+ S
Sbjct: 1051 IAEGAFDIDRNSGKLVVARS--LDREQQSEYRMEIRALDTSAS 1091
Score = 81.0 bits (191), Expect = 2e-13
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AI + + V +++ +E+I GND F + +G++ L K LD + + V + A+
Sbjct: 2249 AIAEQVDVSSSIAFEIIDGNDDNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGAT 2308
Query: 280 QLNNPLKTAQA-RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD--QG 336
+ + + A RV I + D NDN PEF+ Y ++I E P +S+ Q+ A D D
Sbjct: 2309 MMYKGMNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNS 2368
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDR 371
N E YQ+ + G FSID +G L + N DR
Sbjct: 2369 PNSEVVYQIVSGNDGGWFSIDLITGLLYINNNLDYDR 2405
Score = 75.8 bits (178), Expect = 9e-12
Identities = 51/147 (34%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 218 IHAIDQDL--GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A+D DL + + Y+++SGND FS+D + G L++ LD D F L
Sbjct: 2358 ISAVDADLLNSPNSEVVYQIVSGNDGGWFSIDLITGLLYINNNLDYDRG----PTQFNLV 2413
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
++A + K + I L D NDN P+F V Y + EN P G S+ ATD D+
Sbjct: 2414 IRACDSHVLPKCSVHPFVINLTDENDNEPQFPVPEYLEFVGENEPIGISIFTARATDMDR 2473
Query: 336 GENGEFTYQLDD--PKGAFSIDPRSGW 360
GE G Y +D+ G S+D GW
Sbjct: 2474 GEYGRVNYSIDNAMTSGYSSVD--DGW 2498
Score = 72.9 bits (171), Expect = 6e-11
Identities = 55/179 (30%), Positives = 81/179 (45%), Gaps = 10/179 (5%)
Query: 209 HKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQ 268
+ E+ + A D D G+ + Y + GN FS+D G+L LD E + +
Sbjct: 1472 NSELSVIHTVVASDADEGLNGEITYSISGGNIGNKFSIDMNTGALTARP---LDREIHAR 1528
Query: 269 ANTFVLQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+VLQ+ A +P + + + D NDN P+FE+ Y +I E+ P G +VL
Sbjct: 1529 ---YVLQITAQDRGSPTSHQGHCNITVRVEDENDNDPKFELQKYIATIDEDAPIGTTVLT 1585
Query: 328 VMATDKDQGENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
V A D D G N Y L + + F ID +SG +T DRE S V A +
Sbjct: 1586 VKAVDADIGINARIVYSLANVTEWLFDIDSKSGVITTAGH--FDRERQSIYNFMVVATD 1642
Score = 72.9 bits (171), Expect = 6e-11
Identities = 55/179 (30%), Positives = 88/179 (49%), Gaps = 10/179 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D+G+ A + Y L + + LF +DS +G + D E N V+
Sbjct: 1586 VKAVDADIGINARIVYSLANVTEW-LFDIDSKSGVITTAGHFD--RERQSIYNFMVVATD 1642
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ N ++ +V++ + D+NDN P F+ + I + G ++L + ATD DQG
Sbjct: 1643 GGRYN--ARSQSVQVQVIIADVNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGS 1700
Query: 338 NGEFTYQL-DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
NGE Y L D+P A F I+P +G L+ L E L ++V A++ NP V T
Sbjct: 1701 NGEIVYSLNDNPNNAKFRINPNTGALSATQS--LASENGRLLHIEVTARDKGNPPQVAT 1757
Score = 68.5 bits (160), Expect = 1e-09
Identities = 113/493 (22%), Positives = 196/493 (39%), Gaps = 61/493 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +++V L D NDN P F Y S+ G + KV A D D G N +LY
Sbjct: 1867 LYGYCSIKVVLQDENDNAPRFTQQQ-YSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYH 1925
Query: 499 LQRTSNLTITSPFKINPN-TGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ ++ + F I P +G V ++ + ++ L V A+D+ ++ V
Sbjct: 1926 IVDGNH---DNAFIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVN 1982
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++V N+P P V +GT + I ND ++Y +
Sbjct: 1983 VVDV----NDNQPTFP----PNSVISVSEATTVGTVLTSITANDVDTNPPLTYSFGDSPD 2034
Query: 616 EGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE- 672
E F+++ SG + ++ L R ++F+ L ++ T TV V DVND
Sbjct: 2035 EDAKSYFSIDRYSGKVILIKPLDYEAR--HEFQLRILASDSAHVARTLLTVRVTDVNDNP 2092
Query: 673 ------------RGVLL-----KGAHSPIIFH-VKENSAGAAIGQIFHTNMSSIYGNGTG 714
G G HS I F + +++ + I N +
Sbjct: 2093 PQFQQITYHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNA 2152
Query: 715 NVRFLIANQQDVTDDIAIAED---GTIF-TQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
+R+ I + I A D G +F + R + +T+ A + GV +
Sbjct: 2153 AIRYTI-----IPPSIGFAIDALTGQLFVNMSQVHRTRSGTLYLTITAT-DSGVPPLSSS 2206
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD--EGTNALFMYT 828
V + ++ ++ P F + Y I E++ G+ I N+I A+ + ++++
Sbjct: 2207 TTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSVI--TNLIPKAIAEQVDVSSSIAFEI 2264
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--------GLSSEAELI 880
+ G F++ +G + + SLDREK Y+L LV + G +SS +
Sbjct: 2265 IDGNDDNCFEISYPSGAILLV-KSLDREKTDYYELRLVVTEPGATMMYKGMNMSSAIRVT 2323
Query: 881 IMIGDENDNKPEF 893
I + D NDN PEF
Sbjct: 2324 ITVEDANDNAPEF 2336
Score = 65.7 bits (153), Expect = 9e-09
Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 14/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D GV A + Y L G + F + S G + + ELD + N++ +
Sbjct: 261 VSATDPDCGVNAMVNYTLGEGYKKITEFEIRSSTGEVCIAAELDYETR-----NSYEFPI 315
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN----GFSVLQVMATD 332
A+ TA V+I+L D+NDN P F YN+S+ E++P V+ ++ATD
Sbjct: 316 IATDRGGLSTTAM--VKIQLTDVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVATD 373
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G G +Y++ + G F +D +G + V +L + R+ + A +
Sbjct: 374 SDSGSFGTISYRIVAGNEAGIFRMDRLTGEIFVARPNMLSSRSQPYHRLNISASD 428
Score = 65.7 bits (153), Expect = 9e-09
Identities = 50/136 (36%), Positives = 65/136 (47%), Gaps = 27/136 (19%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G+N SA + VT+ +ED NDN P F PY V + E API S+
Sbjct: 2313 GMNMSSA-IRVTITVEDANDNAPEFQPGPYEVAISET------------APIKYSIG--- 2356
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
I A D D N+PNS+V Y IVSGND G F+++ +L + LDYD
Sbjct: 2357 ----------QISAVDADLLNSPNSEVVYQIVSGNDGGWFSIDLI-TGLLYINNNLDYDR 2405
Query: 193 GDKEFQLVIMASGKRI 208
G +F LVI A +
Sbjct: 2406 GPTQFNLVIRACDSHV 2421
Score = 65.3 bits (152), Expect = 1e-08
Identities = 98/429 (22%), Positives = 162/429 (37%), Gaps = 45/429 (10%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I G V +A L E+ + I A D G L+ V++ + DVND+ P F
Sbjct: 288 FEIRSSTGEVCIAAELDYETRNSYEFPIIATDRGGLSTTAMVKIQLTDVNDNRPTFYPRE 347
Query: 1050 YNFNVEEAQYTRRVLGK----VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV- 1104
YN ++ E+ T +L + ATD+D G ++Y I + F + LTG + V
Sbjct: 348 YNVSLRESMPTNSLLSTPVVVIVATDSDSGSFGTISYRIVAGNEAGIFRMDRLTGEIFVA 407
Query: 1105 -NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
L ++ + L + A D G D P FD+ P
Sbjct: 408 RPNMLSSRSQPYHRLNISASDGG-GLRSTHDAEVFISVIDATQRPP---IFDK------P 457
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FIG----NGNGLILYSL 1218
+ + ++ AT + G+ +++ D D + +GN + +L
Sbjct: 458 RYTYYVKEDVKKNTVVGTVSATSSNSGSRGSIRYFIYSGDPDGYFAIDPVSGNIRVASTL 517
Query: 1219 P-QRKNQQNLGLPSLS-STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
+ K Q L + + S T ++ E + P F S + + ENV L
Sbjct: 518 DHETKPQVLLNIQATSGDPPAYGHTQVNIDIEDVNDNPPEFESSTVRISVPENVEIGSPL 577
Query: 1277 VSLNLTEHYENFK-MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N + + Y L+ N F ID R+G L L R D YE + R
Sbjct: 578 YAANAHDKDSGMSGVITYRLSNNGPATGNLFSIDSRSGHLSLARPLD------YETVQR- 630
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTA 1395
H + A D ++ ++V ++DVNDN+P F + + +
Sbjct: 631 ----------HTLIVTASDSGIPSLSTNLTILVEVQDVNDNAPVFERSEYAI--KVSEST 678
Query: 1396 PFGYQVMQL 1404
P Q+MQ+
Sbjct: 679 PSNSQIMQV 687
Score = 63.7 bits (148), Expect = 4e-08
Identities = 39/95 (41%), Positives = 54/95 (56%), Gaps = 5/95 (5%)
Query: 812 IKATDADEGTNALFMYTLFGEGKEM---FDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
+ ATD D G NA+ YTL GEG + F++ +TG V I LD E + Y+ ++A
Sbjct: 261 VSATDPDCGVNAMVNYTL-GEGYKKITEFEIRSSTGEV-CIAAELDYETRNSYEFPIIAT 318
Query: 869 DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
D GGLS+ A + I + D NDN+P F E N +R
Sbjct: 319 DRGGLSTTAMVKIQLTDVNDNRPTFYPREYNVSLR 353
Score = 62.1 bits (144), Expect = 1e-07
Identities = 75/276 (27%), Positives = 110/276 (39%), Gaps = 30/276 (10%)
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
V ATD D G NA + Y + + FEI TG + + ELD ET + Y ++A D
Sbjct: 261 VSATDPDCGVNAMVNYTLGEGYKKITEFEIRSSTGEVCIAAELDYETRNSYEFPIIATDR 320
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
G DVNDN P FY E+ + + ++ S ++ V AT
Sbjct: 321 GGLSTTAMVKIQLT---DVNDNRPTFYP----REYNVSLRESMPTNSLLSTPVV-VIVAT 372
Query: 1186 IEENAPIGTTVAKVFANDTD------------FIGNGNGLILYSLP-QRKNQQNLGLPSL 1232
++ GT ++ A + F+ N L S P R N L
Sbjct: 373 DSDSGSFGTISYRIVAGNEAGIFRMDRLTGEIFVARPNMLSSRSQPYHRLNISASDGGGL 432
Query: 1233 SST--AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKM 1290
ST A + ++V D + DKP + YY E + N V VS + +
Sbjct: 433 RSTHDAEVFISVIDATQRPPIFDKPRY--TYYVKE-DVKKNTVVGTVSATSSNSGSRGSI 489
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
RY+I + D D F IDP +G + + + D E K
Sbjct: 490 RYFIYS-GDPD--GYFAIDPVSGNIRVASTLDHETK 522
Score = 58.8 bits (136), Expect = 1e-06
Identities = 50/167 (29%), Positives = 81/167 (48%), Gaps = 15/167 (8%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ-----ASQLNN 283
A L YE+ G F +DSV G + D +++ +V + AS +
Sbjct: 1376 ANLTYEIPKGVGDDHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSK 1435
Query: 284 PLKTAQ-ARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQ-VMATDKDQGENGE 340
+ A + + + D+ND+ PEF Y +++ EN + SV+ V+A+D D+G NGE
Sbjct: 1436 DMSQFDVATLVVRITDVNDHAPEFLPGSCYPLAVPEN--SELSVIHTVVASDADEGLNGE 1493
Query: 341 FTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
TY + FSID +G LT R LDRE H+ +++ A++
Sbjct: 1494 ITYSISGGNIGNKFSIDMNTGALTAR---PLDREIHARYVLQITAQD 1537
Score = 57.2 bits (132), Expect = 3e-06
Identities = 47/174 (27%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D G A + Y ++ GN F ++ + ++ + LD E + + L+V
Sbjct: 1909 VNAFDTDQGSNAHILYHIVDGNHDNAFIIEPAFSGI-VKTNIVLDREIR---DKYKLKVI 1964
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P T A + + ++D+NDN P F + IS+ E G + + A D D
Sbjct: 1965 ATDEGVPQMTGTATINVNVVDVNDNQPTFPPNSV-ISVSEATTVGTVLTSITANDVD--T 2021
Query: 338 NGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N TY +D K FSID SG + + LD EA ++++ A ++
Sbjct: 2022 NPPLTYSFGDSPDEDAKSYFSIDRYSGKVILIKP--LDYEARHEFQLRILASDS 2073
Score = 50.0 bits (114), Expect = 5e-04
Identities = 41/177 (23%), Positives = 76/177 (42%), Gaps = 8/177 (4%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L + EN PIG +I A D+D G G++ Y ++ + S + K V
Sbjct: 2450 LEFVGENEPIGISIFTARATDMDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGV 2509
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ + + ++ + + A D G + + VR+ ++ ++ P F + Y F ++
Sbjct: 2510 INSNAVF--DYEEKNRYSFTLRATDTGGKSKTVKVRIMIESRDEFSPQFTERTYRFILKT 2567
Query: 1057 AQY----TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
V+G V ATD D G + + Y Q + F+++ TG + V +LD
Sbjct: 2568 PDTGHLPVGYVVGHVTATDRDRGPDGRIVY--QLTTQHPYFKMNRTTGAILVKKKLD 2622
Score = 50.0 bits (114), Expect = 5e-04
Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 11/129 (8%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
KLF +DSV+G + D + + N + ++A+ KT + R+ IE D +
Sbjct: 2499 KLFKVDSVSGVINSNAVFDYE-----EKNRYSFTLRATDTGGKSKTVKVRIMIESRD--E 2551
Query: 302 NLPEFEVDFYNISI----VENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
P+F Y + +LP G+ V V ATD+D+G +G YQL F ++
Sbjct: 2552 FSPQFTERTYRFILKTPDTGHLPVGYVVGHVTATDRDRGPDGRIVYQLTTQHPYFKMNRT 2611
Query: 358 SGWLTVRNQ 366
+G + V+ +
Sbjct: 2612 TGAILVKKK 2620
Score = 48.0 bits (109), Expect = 0.002
Identities = 69/251 (27%), Positives = 102/251 (40%), Gaps = 29/251 (11%)
Query: 415 EKTTYVFPDKVGTKT-ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA 473
EKT Y V T+ + Y + S + V +T+ DANDN P F P YE ++ A
Sbjct: 2291 EKTDYYELRLVVTEPGATMMYKGMNMSSAIRVTITVEDANDNAPEFQPGP-YEVAISETA 2349
Query: 474 KVGTVIGKVKAVDPDL--GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE-- 529
+ IG++ AVD DL N V+Y + ++ F I+ TG + + + +
Sbjct: 2350 PIKYSIGQISAVDADLLNSPNSEVVYQIVSGND---GGWFSIDLITGLLYINNNLDYDRG 2406
Query: 530 -GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
+ L + A D P + S+ I +T N+P P Y +VG N I
Sbjct: 2407 PTQFNLVIRACDSHVLP---KCSVHPFVINLT-DENDNEPQFP---VPEYLEFVGENEPI 2459
Query: 589 GTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVP--------FAVEERSGVI--TVVDDLS 636
G S+ R D E V+Y + + G F V+ SGVI V D
Sbjct: 2460 GISIFTARATDMDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGVINSNAVFDYE 2519
Query: 637 RYNRPMYDFEA 647
NR + A
Sbjct: 2520 EKNRYSFTLRA 2530
Score = 42.3 bits (95), Expect = 0.099
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 33/170 (19%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
+ FS+D +G + L K LD +A H Q L++ AS + A+ + + + D+N
Sbjct: 2038 KSYFSIDRYSGKVILIKPLDYEARHEFQ-----LRILAS---DSAHVARTLLTVRVTDVN 2089
Query: 301 DNLPEFEVDFYNISIV-ENLP-----------------------NGFSVLQVMATDKDQG 336
DN P+F+ Y+ + N P + +++ V ATD D
Sbjct: 2090 DNPPQFQQITYHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSE 2149
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N Y + P F+ID +G L V N + + R +L + + A ++
Sbjct: 2150 NNAAIRYTIIPPSIGFAIDALTGQLFV-NMSQVHRTRSGTLYLTITATDS 2198
Score = 42.3 bits (95), Expect = 0.099
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 12/178 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D A +RY +I + F++D++ G LF+ ++ H ++ T L +
Sbjct: 2141 VNATDSDSENNAAIRYTIIPPSIG--FAIDALTGQLFV----NMSQVHRTRSGTLYLTIT 2194
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM--ATDKDQ 335
A+ P ++ V +E+ + P F Y +SI E+ P G + ++ A +
Sbjct: 2195 ATDSGVPPLSSSTTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQV 2254
Query: 336 GENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+ +++ D F I SG + + LDRE +++ E +++
Sbjct: 2255 DVSSSIAFEIIDGNDDNCFEISYPSGAILLVKS--LDREKTDYYELRLVVTEPGATMM 2310
Score = 41.5 bits (93), Expect = 0.17
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q+ + V ++D NDN P F P+++ S+ VGTV+ + A D D N + Y
Sbjct: 1972 QMTGTATINVNVVDVNDNQPTFPPNSV--ISVSEATTVGTVLTSITANDVD--TNPPLTY 2027
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASD 540
+ + S F I+ +G V + + E RH L + ASD
Sbjct: 2028 SFGDSPDEDAKSYFSIDRYSGKVILIKPLDYEARHEFQLRILASD 2072
Score = 41.1 bits (92), Expect = 0.23
Identities = 16/44 (36%), Positives = 28/44 (63%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK 115
+G+ +S L++ V ++DVNDN P+F + Y + V E TP+ +
Sbjct: 640 SGIPSLSTNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQ 683
Score = 36.3 bits (80), Expect = 6.5
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
ATD+D GINA +RY ++ F I+P+SG + L R+ ++
Sbjct: 810 ATDADAGINAVVRYSLIPSNT-SFQINPISGEITTRDRLDRETKSIY 855
Score = 35.9 bits (79), Expect = 8.6
Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
Query: 1440 QATDSDIGINADIRYQIL----NEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+A D D G+NA I Y IL ++ F IDP++G +R A+L + ++
Sbjct: 913 RAIDRDYGVNASITYSILKGRDSDGHGMFTIDPITGLIRTKASLDHEEKTIY 964
Score = 35.9 bits (79), Expect = 8.6
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVFGF 1489
+A D+DIGINA I Y + N F ID SG + R+ ++ F
Sbjct: 1587 KAVDADIGINARIVYSLANVTEWLFDIDSKSGVITTAGHFDRERQSIYNF 1636
Score = 35.9 bits (79), Expect = 8.6
Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 13/128 (10%)
Query: 1011 SEFRLNISALDGGNLNDNISVRVFV---KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
++F L I A D L SV FV D ND+ P F Y V E + +
Sbjct: 2408 TQFNLVIRACDSHVL-PKCSVHPFVINLTDENDNEPQFPVPEYLEFVGENEPIGISIFTA 2466
Query: 1068 DATDADFGQNANLTYFIQPSDTD---------LPFEISPLTGVLSVNGELDRETEDKYIL 1118
ATD D G+ + Y I + T F++ ++GV++ N D E +++Y
Sbjct: 2467 RATDMDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGVINSNAVFDYEEKNRYSF 2526
Query: 1119 TVVARDNG 1126
T+ A D G
Sbjct: 2527 TLRATDTG 2534
Score = 35.9 bits (79), Expect = 8.6
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 12/85 (14%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKS----NAKVGTVIGKVKAVDPDLGQNGMVLYD 498
V V + + ++ +P F Y F +K+ + VG V+G V A D D G +G ++Y
Sbjct: 2540 VKVRIMIESRDEFSPQFT-ERTYRFILKTPDTGHLPVGYVVGHVTATDRDRGPDGRIVY- 2597
Query: 499 LQRTSNLTITSP-FKINPNTGTVSV 522
LT P FK+N TG + V
Sbjct: 2598 -----QLTTQHPYFKMNRTTGAILV 2617
>UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenopus
tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
Length = 2474
Score = 189 bits (461), Expect = 4e-46
Identities = 254/1025 (24%), Positives = 419/1025 (40%), Gaps = 148/1025 (14%)
Query: 410 TNAPLEKTTYVFPDKVGTKTENIEYYDE-----QLMSFVNVEVTLLDANDNNPVFVPSNL 464
TN + T+++ D+ T NI +L + ++ + + D NDN P+F S
Sbjct: 836 TNGEIRTTSFL--DRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTY 893
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS--NLTITSPFKINPNTGTVSV 522
+ ++N G+ I ++ A DPD G N ++Y + T+ ++ I+S F IN TG +
Sbjct: 894 VAYLSENNLP-GSSIYRINAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIETGVLYA 952
Query: 523 AESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
S E + + A D +PS + V+ I + N IP+F Y+
Sbjct: 953 QRSFDYEHDKEFQIGITARDH-GSPSLSSNTTLVIHI-IDHDANDN---IPEFSKEVYKV 1007
Query: 581 WVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV---PFAVEERSGVITVVDDL 635
+ N + T+V + D E ++Y + + F + SG IT DL
Sbjct: 1008 KMSENTPVNTTVLSVDATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDL 1067
Query: 636 SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG-VLLKGAHSPIIFHVKENSAG 694
+ Y+ A+ + T + ++D ND + + +PI E+S
Sbjct: 1068 DFESVQSYEI-AIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPI----PEDSMP 1122
Query: 695 AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRM 754
+ + + NG + + L A + + + I T LDREK Y +
Sbjct: 1123 GTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVS--SSSRYYRIITASFLDREKVPWYNI 1180
Query: 755 TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
T++A +KG + + + + D NDNPPVF TY ++ EN+ G+ I I+A
Sbjct: 1181 TILAT-DKGSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYR---IQA 1236
Query: 815 TDADEGTNALFMYTLFG------EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
D D G NA +Y++ F ++ +GV+ + S D E+ M+ + + AR
Sbjct: 1237 FDFDSGNNAKVVYSILNTYIQDIPVSAYFSINVVSGVL-YAQRSFDYEQHQMFSMEITAR 1295
Query: 869 DTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
D+G L+S LII I D+NDN PE N G ++ E+ P
Sbjct: 1296 DSGSPPLNSNITLIIYIIDQNDNAPEILYPSPNG-------------GGSSLFEMVP--- 1339
Query: 927 FALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
L E + T +I A+D DSG N + Y F IP S S
Sbjct: 1340 ------------LASEQGSLITKVI---AVDADSGHNSWLSYHF-----IPMSDPSP--- 1376
Query: 987 EVKRYFVINERHGHVIVARSLPPESE----FRLNISALDGGN--LNDNISVRVFVKDVND 1040
F IN+ G + + P + E +L ++A DGGN +R+ + DVND
Sbjct: 1377 -----FSINQYTGEIRTCQK-PLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAITDVND 1430
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEIS 1096
H P+F + Y ++ E+ + +V+ATD D G NA +TY I+ S L F I+
Sbjct: 1431 HIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSIN 1490
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
P +G + L+ E + Y ++V A+D +G D NDN P F
Sbjct: 1491 PASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVF-- 1548
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI----GTTVAKVFANDTDFIGN 1209
++ + E+ +++ +V ++ N I T F I
Sbjct: 1549 TQQVYKISISESAPINS----TVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINP 1604
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSS----------TAILMVTVADVPDEVEMSDKPVFIS 1259
NG I + + P S+ TA++ + V D D + PVF
Sbjct: 1605 ANGEIKTKVSNINTEDFPVSPYFSTSDGGNPLRTGTALIRIIVTDSNDNL-----PVFTQ 1659
Query: 1260 RYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRT-FVIDPRNGTLY 1316
Y++ + EN +N+ V +++ + N K+ Y I + + + F I+P G +
Sbjct: 1660 EVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNNFYTSIFHINPATGEIT 1719
Query: 1317 LVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDN 1376
+ + E K+ YE+ V+AE G KV++ I DVNDN
Sbjct: 1720 TKENLNFENKEHYEMSVQAED-------------------GGGLVAQSKVLIEITDVNDN 1760
Query: 1377 SPKFT 1381
P FT
Sbjct: 1761 VPVFT 1765
Score = 188 bits (459), Expect = 8e-46
Identities = 239/949 (25%), Positives = 400/949 (42%), Gaps = 110/949 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
VT++D NDN P ++L + +A GT++ ++ D D G NG V +S T
Sbjct: 183 VTVVDVNDNAPEMTVTSL-SLPVPEDATHGTIVAIIRVRDRDSGNNGKVNC---YSSTPT 238
Query: 507 ITSPFKINPN-TGTVS-VAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ FKINP +G S + SP+ + + + + A D+ Y V++ +
Sbjct: 239 L---FKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEG-------YPSLSVSMTINV 288
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-- 619
+ P F + ++ N G+ + + +D+ + ND + + V
Sbjct: 289 EVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDS-DINDNAPLFISDNSNSVSAM 347
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
+S V L R N+ Y A E + +LSI V + DVND + +
Sbjct: 348 LVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVNDNAPLFQQ 407
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
A + IF + N G+ QI+ + S + TG F+ + + + D ++ +
Sbjct: 408 TADT--IFIRENNPPGS---QIYIVSASD---SDTGQNSFITYSLKSPSKDNK-SKSLVL 458
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+ LDREK+ + +T+ A + G +G Q+ I ++D NDN P F H Y I E
Sbjct: 459 VLNQALDREKQASHLLTLTAA-DCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVSIPE 517
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGDSLD 854
N +G+ I ++KATD DEG N + Y+ G K++F +++N G V G LD
Sbjct: 518 NYAVGSLIV---VLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKG-LLD 573
Query: 855 REKKIMYKLSLVAR-----DTG--GLSSEAELIIMIGDENDNKPEFNQ------IEEN-- 899
E K Y++ + D G LS+ A + + D NDN P F + I EN
Sbjct: 574 YENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAENIL 633
Query: 900 --SKV-RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
S + ++ K +G + + + V + + P++ +G + KL A+
Sbjct: 634 PGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHF--ISINPDSGNVGHLVTKLRAV 691
Query: 957 DLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN 1016
D D+G N + YE + P S + V Y N + S + +
Sbjct: 692 DADAGYNAWLTYEMD-----PVS--NTTLFSVDSYSGENTYKLVTVGKLDREKSSSYNIT 744
Query: 1017 ISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTW----YNFNVEEAQYTRRVLGKVDAT 1070
++ D G L+ ++ V V D+ND+ P F+K Y + E + +V+AT
Sbjct: 745 VTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEKCTNKEVYKVRISENSPINSTVIRVNAT 804
Query: 1071 DADFGQNANLTY-FIQPSDTDL---PFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D D G N+ +TY F + SD L F+I+P G + LDRE +Y +T+++ D G
Sbjct: 805 DKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRTTSFLDRENTSQYNITILSTDRG 864
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF--ESVMMIPVYKA 1184
DVNDN+P F K LS +N S+ I Y
Sbjct: 865 -SPKLSTVKHIRLNISDVNDNAPIFK--------KSTYVAYLSENNLPGSSIYRINAYDP 915
Query: 1185 TIEENAPI-----GTTVAKVFANDTDFIGNGNGLIL----YSLPQRKNQQ------NLGL 1229
+NA I GT + + + I G++ + K Q + G
Sbjct: 916 DTGDNAKIIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHDKEFQIGITARDHGS 975
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--N 1287
PSLSS L++ + D + P F Y++++ EN ++S++ T+ E N
Sbjct: 976 PSLSSNTTLVIHII---DHDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLN 1032
Query: 1288 FKMRYYILNENDTDIRR-TFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ Y +D + TF I+P +G + R D E +YE+ + A
Sbjct: 1033 AQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEA 1081
Score = 146 bits (354), Expect = 4e-33
Identities = 191/862 (22%), Positives = 349/862 (40%), Gaps = 69/862 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S +++ V + DVNDN P+F + + + E P G + + + PL
Sbjct: 276 GYPSLSVSMTINVEVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPL 335
Query: 133 TVPRG--------LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
+ +T K + + N + +++ D+G +L S + +
Sbjct: 336 FISDNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEI 395
Query: 185 RKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
V D + + + +I + A D D G + + Y L S
Sbjct: 396 SDVNDNAPLFQQTADTIFIRENNPPGSQIYI---VSASDSDTGQNSFITYSLKSP----- 447
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
S D+ + SL L LD E QA+ +L + A+ P ++ ++ I + D+NDN
Sbjct: 448 -SKDNKSKSLVLVLNQALDREK--QAS-HLLTLTAADCGTPKRSGTTQIRILVQDVNDNA 503
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-----PKGAFSIDPRS 358
P F Y +SI EN G ++ + ATD D+GENG Y K F I+ +
Sbjct: 504 PTFRHPIYRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNN 563
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKT 417
G + ++ + + + + ++ +T + + + + I + + N PL +
Sbjct: 564 GEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGIPALSTTAYIY-FSVDDINDNPPLFTEE 622
Query: 418 TYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA-KVG 476
Y F ++ + LL A + V S + S+ ++ VG
Sbjct: 623 LYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHFISINPDSGNVG 682
Query: 477 TVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKIN-PNT-GTVSVAE-SPILEGRHA 533
++ K++AVD D G N + Y++ SN T+ S + NT V+V + +
Sbjct: 683 HLVTKLRAVDADAGYNAWLTYEMDPVSNTTLFSVDSYSGENTYKLVTVGKLDREKSSSYN 742
Query: 534 LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSV 592
+ V +D P + +L V ++ N P Y+ + N I ++V
Sbjct: 743 ITVTVTDSGTPPLSTQKTLYVEVSDLN----DNPPTFEKCTNKEVYKVRISENSPINSTV 798
Query: 593 GQIRVNDAFE--QNDVSYDLLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEA 647
++ D E + ++Y + + F + +G I L R N Y+
Sbjct: 799 IRVNATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRTTSFLDRENTSQYNITI 858
Query: 648 VALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
++ + LS V + +++ DVND + K + + + + N G++I +I
Sbjct: 859 LSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTY--VAYLSENNLPGSSIYRI------ 910
Query: 707 SIYGNGTG-NVRFLIANQQDVTDDIAIA-------EDGTIFTQKPLDREKRDVYRMTVIA 758
+ Y TG N + + + DIAI+ E G ++ Q+ D E +++ + A
Sbjct: 911 NAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHDKEFQIGITA 970
Query: 759 -EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
+ +S + I D NDN P F Y+ + EN+ + T + + ATD
Sbjct: 971 RDHGSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVNTTVLS---VDATDK 1027
Query: 818 DEGTNALFMYTLFGEGKEM-----FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
DEG NA Y+ FD++ +G + D LD E Y++++ A D GG
Sbjct: 1028 DEGLNAQITYSFSKTSDNQLHTGTFDINPTSGKITTKRD-LDFESVQSYEIAIEAMDGGG 1086
Query: 873 LSSEAELIIMIGDENDNKPEFN 894
++ +++I I DENDN PE +
Sbjct: 1087 FVAQTKVLIEIIDENDNAPEIS 1108
Score = 127 bits (306), Expect = 3e-27
Identities = 127/484 (26%), Positives = 207/484 (42%), Gaps = 33/484 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
+ + + D NDN PVF +Y+ S+ +A + + + V A D D G NG + Y RT+
Sbjct: 1534 LRIIVTDYNDNVPVFT-QQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAE 1592
Query: 504 NLTITSPFKINPNTGTVSVAESPI-LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
N T F INP G + S I E ++ NP R A++ I VT
Sbjct: 1593 NAFHTQMFNINPANGEIKTKVSNINTEDFPVSPYFSTSDGGNP--LRTGTALIRIIVT-- 1648
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV-- 618
+ ++P F Y+ V N I ++V + D E + ++Y + +
Sbjct: 1649 --DSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNNFYT 1706
Query: 619 -PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F + +G IT ++L+ N+ Y+ +V ++ L + + + DVND V
Sbjct: 1707 SIFHINPATGEITTKENLNFENKEHYEM-SVQAEDGGGLVAQSKVLIEITDVNDNVPVFT 1765
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ + + ENS + N F ++ D +
Sbjct: 1766 QAVYKA---SISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSFHLDSSTGRFYR 1822
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T+ LDREK +Y +T++A +KG + + + I D NDNPPVF + ++
Sbjct: 1823 IVTKSALDREKTALYNITIVAT-DKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLP 1881
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE------MFDVDENTGVVKFIGD 851
EN+ G+ I I+A+D D G NA +Y++ E F ++ TGV+ +
Sbjct: 1882 ENNLPGSSIYR---IQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIETGVL-YAQR 1937
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
S D E+ +++ + A D G S A + I + D NDN P F Q E KV I
Sbjct: 1938 SFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQ--EVYKVSISENIP 1995
Query: 910 LNGT 913
+N T
Sbjct: 1996 INST 1999
Score = 126 bits (304), Expect = 5e-27
Identities = 128/489 (26%), Positives = 221/489 (45%), Gaps = 44/489 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
+ + + D+NDN PVF +Y+ S+ NA + + + + A D D G N + Y + +TS
Sbjct: 1643 IRIIVTDSNDNLPVFT-QEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSK 1701
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
N TS F INP TG ++ E+ E + + + V+A D ++ + V IE+T
Sbjct: 1702 NNFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQSK-----VLIEIT- 1755
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-- 619
++P F A Y+ + N + T+V + VN + ++ +++ + +
Sbjct: 1756 ---DVNDNVPVFTQAVYKASISENSPVNTTV--LYVNATDKDEGINAQIVYSFSKTSENS 1810
Query: 620 FAVEERSGV---ITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGV 675
F ++ +G I L R +Y+ VA + + LS + + DVND V
Sbjct: 1811 FHLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPV 1870
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD----VTDDIA 731
+K S + ++ EN+ + I+ S + V + I++ + ++ +
Sbjct: 1871 FMK---SKDVAYLPENNLPGS--SIYRIQASDLDTGDNAKVIYSISSMDNEDFPISSYFS 1925
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I E G ++ Q+ D E+ +++ + A + +G + I + D NDN PVF
Sbjct: 1926 INIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVR-SGTALIRIAVTDANDNLPVFTQE 1984
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK--- 847
Y+ I EN I + + + ATD DEGTNA Y L + N+ + K
Sbjct: 1985 VYKVSISENIPINSTVL---TVNATDRDEGTNAQ-SYRLSDNQYFRLNEKTNSDLSKTPE 2040
Query: 848 -FIGDSLDREKKIMYKLSLVARDTGG-LSSEAELI-IMIGDENDNKPEFNQIEENSKVRI 904
+ LDRE + +++L L A D G L + LI I++ D NDN P F Q E KV I
Sbjct: 2041 LVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQ--EVYKVSI 2098
Query: 905 HRETKLNGT 913
+N +
Sbjct: 2099 SENAPINSS 2107
Score = 116 bits (279), Expect = 5e-24
Identities = 122/452 (26%), Positives = 198/452 (43%), Gaps = 45/452 (9%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN PVF S +Y+ S+ NA GT++ K+ A D D+G+NG Y+ + + S
Sbjct: 91 DVNDNPPVFNQS-VYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSL 149
Query: 511 FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F ++ TG V V E + + ++A D V ++V
Sbjct: 150 FSLDKYTGEVWVKGELDYEKSNTYEVLIDALDN------------VTVVDV-------ND 190
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEER-SG 627
+ P+ V + GT V IRV D N+ + F + SG
Sbjct: 191 NAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYS--STPTLFKINPAFSG 248
Query: 628 VITVV--DDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+++ L R + Y A E +LS+ V V DVND + + S
Sbjct: 249 DFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTINVEVSDVNDNAPLFQQS--SDT 306
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-EDGTIFTQKP 743
IF + N G+ I + ++ S I N F+ N V+ + A + P
Sbjct: 307 IFIRENNPPGSHIYTVSASD-SDINDNAP---LFISDNSNSVSAMLVTAPKSAQPAVDAP 362
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE + Y++ + A+ ++G S + + + I D NDN P+F+ FI EN+ G
Sbjct: 363 LDRENKSEYQVVITAK-DEGSPSLSISMTINVEISDVNDNAPLFQQTADTIFIRENNPPG 421
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
++I I+ A+D+D G N+ Y+L K+ +++ +V + +LDREK+ + L
Sbjct: 422 SQI---YIVSASDSDTGQNSFITYSLKSPSKD----NKSKSLVLVLNQALDREKQASHLL 474
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+L A D G S ++ I++ D NDN P F
Sbjct: 475 TLTAADCGTPKRSGTTQIRILVQDVNDNAPTF 506
Score = 111 bits (268), Expect = 1e-22
Identities = 133/498 (26%), Positives = 210/498 (42%), Gaps = 41/498 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL S + + + D NDN PVF+ S + ++N G+ I +++A D D G N V+Y
Sbjct: 1850 QLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLP-GSSIYRIQASDLDTGDNAKVIY 1908
Query: 498 DLQRTSN--LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
+ N I+S F IN TG + S E + + ASD NP R A
Sbjct: 1909 SISSMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASD-GGNPV--RSGTA 1965
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLH 612
++ I VT ++P F Y+ + N+ I ++V + D E N SY L
Sbjct: 1966 LIRIAVTDA----NDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQSYRL-- 2019
Query: 613 GYEEGVPFAVEERSG-------VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH 665
+ F + E++ + + L R + +++ A + N A +
Sbjct: 2020 --SDNQYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTA-SDGGNPLRTGTALIR 2076
Query: 666 VV--DVNDERGVLLKGAHS-PIIFHVKENSAG---AAIGQIFHTNMSSIYGNGTGNVRFL 719
++ D ND V + + I + NS+ A + TN Y +
Sbjct: 2077 IIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNF 2136
Query: 720 IANQQDVTDDIAIAEDGT-IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ ++ I T + +KPLDRE + + + + A + G G + I +
Sbjct: 2137 YTSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELILTAS-DGGDPVKTGTAIIRIIVT 2195
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMF 837
D NDN PVF A Y+ I EN I + + + ATD DEGTNA Y+ F
Sbjct: 2196 DANDNLPVFTKAVYKVSISENIPINSSVLH---VNATDRDEGTNAQITYSFIKTSVSSYF 2252
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
++ TGV+ + S D E+ + + + A+D G LSS A LII I D+NDN P+
Sbjct: 2253 SINIETGVL-YAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKI-L 2310
Query: 896 IEENSKVRIHRETKLNGT 913
+ I T +N T
Sbjct: 2311 YPSTENMSISENTPINST 2328
Score = 103 bits (248), Expect = 3e-20
Identities = 112/418 (26%), Positives = 177/418 (42%), Gaps = 44/418 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN PI +T+I L A D D G N +I Y SK S + F IN G
Sbjct: 1666 VSENAPINSTVIILTATDKDEGTNAKITYSI--------SKTSKNNFYTS-IFHINPATG 1716
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ +L E++ + +++ A DGG L V + + DVND+ PVF + Y ++ E
Sbjct: 1717 EITTKENLNFENKEHYEMSVQAEDGGGLVAQSKVLIEITDVNDNVPVFTQAVYKASISEN 1776
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
+ V+ATD D G NA + Y + ++ F + TG + LDRE
Sbjct: 1777 SPVNTTVLYVNATDKDEGINAQIVYSFSKT-SENSFHLDSSTGRFYRIVTKSALDREKTA 1835
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y +T+VA D G DVNDN P F ++ PE +N
Sbjct: 1836 LYNITIVATDKG-SPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYL--PE----NNLPGS 1888
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKV----FANDTDFIGNGNGLILYS-----LPQRKNQQ 1225
S+ I +NA + +++ + F + F N +LY+ Q K Q
Sbjct: 1889 SIYRIQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQ 1948
Query: 1226 ------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+ G P S TA++ + V D D + PVF Y++ I EN+ ++++
Sbjct: 1949 IQITASDGGNPVRSGTALIRIAVTDANDNL-----PVFTQEVYKVSISENIPINSTVLTV 2003
Query: 1280 NLTEHYENFKMRYYILNEND--TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N T+ E + Y L++N +T + L L + DRE + +E+I+ A
Sbjct: 2004 NATDRDEGTNAQSYRLSDNQYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTA 2061
Score = 102 bits (244), Expect = 9e-20
Identities = 215/1030 (20%), Positives = 404/1030 (39%), Gaps = 121/1030 (11%)
Query: 73 GLNQISAYLSVTVYI--EDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTI 130
G +S+ ++ ++I D NDN+P F Y V + E TP L
Sbjct: 974 GSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNA 1033
Query: 131 PLTVPRGLTIFKDIRA--FDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+T T + FD + + T D+ + V + A++
Sbjct: 1034 QITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKV 1093
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDR 241
+ D D ++ I + I ++ + P + A+ DQD G + +++
Sbjct: 1094 LIEIIDENDNAPEISIASLSAPIPEDSM-PGTVIALIKVHDQDTGRNGEVDCQILGAAPF 1152
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
++ S S + LD + + + + + A+ +P ++ ++++L D+ND
Sbjct: 1153 QIVSSSSRYYRIITASFLDRE-----KVPWYNITILATDKGSPELSSTKSIKLDLSDVND 1207
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL------DDPKGA-FSI 354
N P F Y + EN G S+ ++ A D D G N + Y + D P A FSI
Sbjct: 1208 NPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILNTYIQDIPVSAYFSI 1267
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL 414
+ SG L Q D E H M++ A+++ + ++ I Q NAP
Sbjct: 1268 NVVSGVLYA--QRSFDYEQHQMFSMEITARDSGSPPLN--SNITLIIYIIDQ--NDNAP- 1320
Query: 415 EKTTYVFPDKVGTKT-ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA 473
+ Y P+ G+ E + EQ + +V +DA+ + ++ + S S
Sbjct: 1321 -EILYPSPNGGGSSLFEMVPLASEQ--GSLITKVIAVDADSGHNSWLSYHFIPMSDPSPF 1377
Query: 474 KVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA 533
+ G+++ L + + ++ L T+ + T + +A + +
Sbjct: 1378 SINQYTGEIRTCQKPLDRENLKIHKLLLTA---FDGGNPVRTGTALIRIAITDV-NDHIP 1433
Query: 534 LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSV 592
+F + + + + V+ + T +G I + + + I +
Sbjct: 1434 MFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPAS 1493
Query: 593 GQIRV--NDAFE---QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEA 647
G+I+ N FE ++S + G +G +R+G + ++ YN + F
Sbjct: 1494 GEIKTKRNLNFEVQKHYEMSVEAKDGATDG---GNPKRTGTALLRIIVTDYNDNVPVFTQ 1550
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
+ + + S N+TV VV D+ G + I + + A FHT M +
Sbjct: 1551 QVYKISISESAPINSTVTVVTATDKD----DGTNGHITYSFSRTAENA-----FHTQMFN 1601
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
I G ++ ++N T+D ++ Y T ++ + +G
Sbjct: 1602 I-NPANGEIKTKVSNIN--TEDFPVSP-----------------YFST--SDGGNPLRTG 1639
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+ ++ + D NDN PVF Y+ + EN+ I + + I+ ATD DEGTNA Y
Sbjct: 1640 TALIRIIV--TDSNDNLPVFTQEVYKVSVSENAPINSTV---IILTATDKDEGTNAKITY 1694
Query: 828 TLFGEGK-----EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM 882
++ K +F ++ TG + ++L+ E K Y++S+ A D GGL ++++++I
Sbjct: 1695 SISKTSKNNFYTSIFHINPATGEIT-TKENLNFENKEHYEMSVQAEDGGGLVAQSKVLIE 1753
Query: 883 IGDENDNKPEFNQ------IEENSKVR-----IHRETKLNGTAGFTIIEVK--PKNKFAL 929
I D NDN P F Q I ENS V ++ K G + +N F L
Sbjct: 1754 ITDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSFHL 1813
Query: 930 DVDQLGPLFLIPENIPIG---TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
D G + I + T + + + D G + +S +I +L +
Sbjct: 1814 D-SSTGRFYRIVTKSALDREKTALYNITIVATDKG-----SPQLSSRKFI---RLDISDV 1864
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDV-NDHFPVF 1045
+ + + +LP S +R+ S LD G DN V + + N+ FP+
Sbjct: 1865 NDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTG---DNAKVIYSISSMDNEDFPI- 1920
Query: 1046 KKTWYNFNVE 1055
++++ N+E
Sbjct: 1921 -SSYFSINIE 1929
Score = 99 bits (238), Expect = 5e-19
Identities = 118/472 (25%), Positives = 199/472 (42%), Gaps = 44/472 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + DANDN PVF +Y+ S+ N + + + V A D D G N Y L
Sbjct: 1967 IRIAVTDANDNLPVFT-QEVYKVSISENIPINSTVLTVNATDRDEGTNAQS-YRLSDNQY 2024
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ + + V E P+ + H L + ASD NP R A++ I VT
Sbjct: 2025 FRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTASDG-GNPL--RTGTALIRIIVT- 2080
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
+ ++P F Y+ + N I +SV + D E + ++Y + E
Sbjct: 2081 ---DSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFY 2137
Query: 620 FAVEERSGVI--TVVDDLSRYNRPM-----YDFEAVALQENANLSIVTNATVH---VVDV 669
+V + VI +V+ +P+ D E + + + T + V D
Sbjct: 2138 TSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDA 2197
Query: 670 NDERGVLLKGAHSPIIF-HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND V K + I ++ NS+ + H N + + + + V+
Sbjct: 2198 NDNLPVFTKAVYKVSISENIPINSS------VLHVNATDRDEGTNAQITYSFI-KTSVSS 2250
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+I E G ++ Q+ D E+ + M V A+ N G S + + I I D+NDN P
Sbjct: 2251 YFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDN-GYPSLSSNATLIIRIIDQNDNAPKI 2309
Query: 788 EHATYEGF-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDE 841
+ + E I EN+ I + + N A+D DEGTNA Y+ MF ++
Sbjct: 2310 LYPSTENMSISENTPINSTVLRVN---ASDMDEGTNAQITYSFSRTSVNSLHASMFSINP 2366
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+G +K + L+ E Y++S+ A+D GG + +++++ I D NDN P F
Sbjct: 2367 TSGEIK-TNNLLNYEAIRDYEISVQAKDGGGFVAHSKILVEITDVNDNPPVF 2417
Score = 99.5 bits (237), Expect = 6e-19
Identities = 124/472 (26%), Positives = 200/472 (42%), Gaps = 75/472 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN G++I ++ A DLD+G N ++ Y +S + + + YF IN G
Sbjct: 1880 LPENNLPGSSIYRIQASDLDTGDNAKVIYSISS--------MDNEDFPISSYFSINIETG 1931
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ RS E EF++ I+A DGGN + +R+ V D ND+ PVF + Y ++
Sbjct: 1932 VLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSIS 1991
Query: 1056 EAQYTRRVLGKVDATDADFGQNA------NLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
E + V+ATD D G NA + YF T+ +P L + LD
Sbjct: 1992 ENIPINSTVLTVNATDRDEGTNAQSYRLSDNQYFRLNEKTNSDLSKTP---ELVLEKPLD 2048
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RET+ + L + A D G D NDN P F E+ + E ++
Sbjct: 2049 RETQSIHELILTASDGG-NPLRTGTALIRIIVTDSNDNLPVF--TQEVYKVSISENAPIN 2105
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFAND-TDFIGNGNGLILYSLP--------- 1219
+ SV+++ NA I +++K N+ + N N +I Y +
Sbjct: 2106 S----SVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKP 2161
Query: 1220 -QRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
R+ Q++ G P + TAI+ + V D D + PVF Y++ I EN
Sbjct: 2162 LDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNL-----PVFTKAVYKVSISEN 2216
Query: 1270 VNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
+ ++ +N T+ E N ++ Y + T + F I+ G LY RS D E
Sbjct: 2217 IPINSSVLHVNATDRDEGTNAQITYSFIK---TSVSSYFSINIETGVLYAQRSFDYEQHK 2273
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
+ + V+A+ Y P + + +++RI D NDN+PK
Sbjct: 2274 EFAMHVQAKDNGY----PSL-------------SSNATLIIRIIDQNDNAPK 2308
Score = 98.3 bits (234), Expect = 1e-18
Identities = 107/437 (24%), Positives = 181/437 (41%), Gaps = 37/437 (8%)
Query: 482 VKAVDPDLGQNGMVLYDLQRT--SNLTITSPFKINPNTGTVSVAESPILEGR---HALFV 536
V A D D GQN + Y L + + ++S INP+ G + + PI E LFV
Sbjct: 1 VSASDSDTGQNSFITYSLTESFIEGVPVSSYIAINPHAGEIRLTR-PITEAEGDAFRLFV 59
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI----PDFMGAPYEFWVGSNVGIGTSV 592
A D P+ + +++I+ + + + D+ P F + Y+ + N GT V
Sbjct: 60 VAEDH-GEPAMTALTQIIISIKDSGFARTHVEDVNDNPPVFNQSVYQCSITENAPKGTLV 118
Query: 593 GQIRVN--DAFEQNDVSYDLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAV 648
++ D + + SY+ E + F++++ +G + V +L Y+
Sbjct: 119 AKLFATDMDVGKNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLID 178
Query: 649 ALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSI 708
AL V VVDVND + + + V E++ I I
Sbjct: 179 ALD-----------NVTVVDVNDNAPEM---TVTSLSLPVPEDATHGTIVAIIRVRDRDS 224
Query: 709 YGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
NG N + A + D ++ PLDREK+ Y++ + A+ ++G S +
Sbjct: 225 GNNGKVNCYSSTPTLFKINP--AFSGDFSLIVNSPLDREKKSEYQVVITAK-DEGYPSLS 281
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+ + + D NDN P+F+ ++ FI EN+ G+ I + A+D+D NA +
Sbjct: 282 VSMTINVEVSDVNDNAPLFQQSSDTIFIRENNPPGSHI---YTVSASDSDINDNAPLFIS 338
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
V + LDRE K Y++ + A+D G LS + + I D
Sbjct: 339 DNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDV 398
Query: 887 NDNKPEFNQIEENSKVR 903
NDN P F Q + +R
Sbjct: 399 NDNAPLFQQTADTIFIR 415
Score = 97.5 bits (232), Expect = 2e-18
Identities = 116/477 (24%), Positives = 204/477 (42%), Gaps = 40/477 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V +E+T D NDN PVF + +Y+ S+ N+ V T + V A D D G N ++Y
Sbjct: 1748 SKVLIEIT--DVNDNVPVFTQA-VYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFS 1804
Query: 501 RTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+TS + F ++ +TG V +S + + AL+ S + S + ++
Sbjct: 1805 KTSE----NSFHLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLD 1860
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEE 616
++ + P P FM + ++ N G+S+ +I+ + D + V Y + E
Sbjct: 1861 IS--DVNDNP--PVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNE 1916
Query: 617 GVP----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVND 671
P F++ +GV+ + + A N S + V D ND
Sbjct: 1917 DFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDAND 1976
Query: 672 ERGVLLKGAHS-PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
V + + I ++ NS + ++ + ++ N++ +D
Sbjct: 1977 NLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQSYRLSDNQYFRLNEKTNSD-- 2034
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+++ + +KPLDRE + ++ + + A + G G + I + D NDN PVF
Sbjct: 2035 -LSKTPELVLEKPLDRETQSIHELILTAS-DGGNPLRTGTALIRIIVTDSNDNLPVFTQE 2092
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF--DVDENTGVVKF 848
Y+ I EN+ I + + I+ ATD DEGTNA Y++ + F V V+ +
Sbjct: 2093 VYKVSISENAPINSSV---IILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYY 2149
Query: 849 --------IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ LDRE + ++L L A D G + A + I++ D NDN P F +
Sbjct: 2150 KIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK 2206
Score = 95.5 bits (227), Expect = 1e-17
Identities = 107/418 (25%), Positives = 180/418 (43%), Gaps = 40/418 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
+ + + D+NDN PVF +Y+ S+ NA + + + + A D D G N + Y + +TS
Sbjct: 2075 IRIIVTDSNDNLPVFT-QEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSE 2133
Query: 504 NLTITSPFKINPN-----TGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
N TS F INP T + E P+ + H L + ASD +P + A++
Sbjct: 2134 NNFYTSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELILTASDG-GDPVKT--GTAII 2190
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG 613
I VT ++P F A Y+ + N+ I +SV + D E + ++Y +
Sbjct: 2191 RIIVTDAND----NLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKT 2246
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVND 671
F++ +GV+ + A ++N S+ +NAT + ++D ND
Sbjct: 2247 SVSSY-FSINIETGVLYAQRSFDYEQHKEFAMHVQA-KDNGYPSLSSNATLIIRIIDQND 2304
Query: 672 ERGVLLKGA--HSPIIFHVKENSAGAAIGQIFH---TNMSSIYGNGTGNVRFLIANQQDV 726
+L + + I + NS + TN Y +V L A+ +
Sbjct: 2305 NAPKILYPSTENMSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSI 2364
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G I T L+ E Y ++V A+ G ++ + ++ + I D NDNPPV
Sbjct: 2365 NPT-----SGEIKTNNLLNYEAIRDYEISVQAKDGGGFVAHS---KILVEITDVNDNPPV 2416
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
F + Y ++ EN+ G I I A D D G NA +Y+++ ++ F VD G
Sbjct: 2417 FIKSAYTIYLPENNLPGATIYR---IHALDLDMGDNAKVIYSIY-VSEKYFSVDLENG 2470
Score = 91.9 bits (218), Expect = 1e-16
Identities = 88/304 (28%), Positives = 132/304 (43%), Gaps = 40/304 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFN--SEVYIPPSKLSADALEVKRYFVINER 997
I EN PI +++I L A D D G N QI Y + SE S + + V Y ++N
Sbjct: 2098 ISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINP--VIYYKIVNTE 2155
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+++ + L E++ L ++A DGG+ +R+ V D ND+ PVF K Y +
Sbjct: 2156 ---LMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVS 2212
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ E + V+ATD D G NA +TY + F I+ TGVL D E
Sbjct: 2213 ISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQH 2272
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
++ + V A+DNG D NDN+PK +P + +S
Sbjct: 2273 KEFAMHVQAKDNG-YPSLSSNATLIIRIIDQNDNAPKIL---------YPSTENMS---- 2318
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK-NQQNLGLPSL 1232
I EN PI +TV +V A+D D N I YS + N + + S+
Sbjct: 2319 ------------ISENTPINSTVLRVNASDMD--EGTNAQITYSFSRTSVNSLHASMFSI 2364
Query: 1233 SSTA 1236
+ T+
Sbjct: 2365 NPTS 2368
Score = 89.0 bits (211), Expect = 9e-16
Identities = 122/475 (25%), Positives = 196/475 (41%), Gaps = 62/475 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P GT + KL A D+D G NG+ YEF+ +P LS F +++ G
Sbjct: 108 ITENAPKGTLVAKLFATDMDVGKNGETSYEFSK--LVPERMLS--------LFSLDKYTG 157
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V V L E + + + I ALD V V DVND+ P T + V E
Sbjct: 158 EVWVKGELDYEKSNTYEVLIDALD----------NVTVVDVNDNAPEMTVTSLSLPVPED 207
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP-LTGVLS--VNGELDRETED 1114
++ + D D G N + + S T F+I+P +G S VN LDRE +
Sbjct: 208 ATHGTIVAIIRVRDRDSGNNGKVNCY---SSTPTLFKINPAFSGDFSLIVNSPLDREKKS 264
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+Y + + A+D G DVNDN+P F + + + E + +H
Sbjct: 265 EYQVVITAKDEG-YPSLSVSMTINVEVSDVNDNAPLFQQSSDTIFIR--ENNPPGSH--- 318
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
+ + + I +NAP+ F +D N +L + P + Q + P
Sbjct: 319 -IYTVSASDSDINDNAPL-------FISDN---SNSVSAMLVTAP-KSAQPAVDAPLDRE 366
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEE-NVNAPVELVSLNLTEHYENFK--MR 1291
V DE S + IS +EI + N NAP+ + + EN +
Sbjct: 367 NKSEYQVVITAKDEGSPS---LSISMTINVEISDVNDNAPLFQQTADTIFIRENNPPGSQ 423
Query: 1292 YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPV 1351
YI++ +D+D + I Y ++SP ++ K V+V + ++ H++
Sbjct: 424 IYIVSASDSDTGQNSFI------TYSLKSPSKDNKSKSLVLVLNQALDREKQASHLLTLT 477
Query: 1352 AEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV-TAIPTTAPFGYQVMQLK 1405
A D ++ + ++DVNDN+P F P+ +IP G ++ LK
Sbjct: 478 AADCGTPKRSGTTQIRILVQDVNDNAPTF---RHPIYRVSIPENYAVGSLIVVLK 529
Score = 88.2 bits (209), Expect = 2e-15
Identities = 93/366 (25%), Positives = 151/366 (41%), Gaps = 43/366 (11%)
Query: 50 QNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDEL 109
+ V +F++ +G + VR G L +I+ + D NDN+P+F Y V++ E
Sbjct: 1942 EQVKEFQIQITASDGGNPVRSGTALIRIA--------VTDANDNLPVFTQEVYKVSISEN 1993
Query: 110 TPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPN-----------SD 158
P F+ + D TP
Sbjct: 1994 IPINSTVLTVNATDRDEGTNAQSYRLSDNQYFRLNEKTNSDLSKTPELVLEKPLDRETQS 2053
Query: 159 VHYSIVSGNDDGHFALESSHKPVLLLRKVLD-YDAGDKEFQLVIMASGKRIHKEILFPEP 217
+H I++ +D G+ + +++ D +E V ++ I+ ++
Sbjct: 2054 IHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVII--- 2110
Query: 218 IHAIDQDLGVGATLRYELISGNDRK----LFSLDSV------NGSLFLEKELDLDAEHNL 267
+ A D+D G A + Y + ++ +F+++ V N L LEK LD + + +
Sbjct: 2111 LTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKPLDRETQKDH 2170
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ L + AS +P+KT A + I + D NDNLP F Y +SI EN+P SVL
Sbjct: 2171 E-----LILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLH 2225
Query: 328 VMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
V ATD+D+G N + TY FSI+ +G L Q D E H M V AK+
Sbjct: 2226 VNATDRDEGTNAQITYSFIKTSVSSYFSINIETGVLYA--QRSFDYEQHKEFAMHVQAKD 2283
Query: 386 TN-PSV 390
PS+
Sbjct: 2284 NGYPSL 2289
Score = 86.6 bits (205), Expect = 5e-15
Identities = 71/221 (32%), Positives = 104/221 (47%), Gaps = 25/221 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIPI ++++ +NA D D G N QI Y F K S V YF IN G
Sbjct: 2213 ISENIPINSSVLHVNATDRDEGTNAQITYSF--------IKTS-----VSSYFSINIETG 2259
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFP-VFKKTWYNFNV 1054
+ RS E EF +++ A D G +L+ N ++ + + D ND+ P + + N ++
Sbjct: 2260 VLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSI 2319
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP---FEISPLTGVLSVNGELDR 1110
E + +V+A+D D G NA +TY F + S L F I+P +G + N L+
Sbjct: 2320 SENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNY 2379
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E Y ++V A+D G DVNDN P F
Sbjct: 2380 EAIRDYEISVQAKDGG---GFVAHSKILVEITDVNDNPPVF 2417
Score = 84.6 bits (200), Expect = 2e-14
Identities = 107/457 (23%), Positives = 183/457 (40%), Gaps = 55/457 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIR-YEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+PE+ GT + + D DSG NG++ Y ++ S D + + E+
Sbjct: 204 VPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLFKINPAFSGDFSLIVNSPLDREK- 262
Query: 999 GHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+SE+++ I+A D G +L+ ++++ V V DVND+ P+F+++ + E
Sbjct: 263 -----------KSEYQVVITAKDEGYPSLSVSMTINVEVSDVNDNAPLFQQSSDTIFIRE 311
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ V A+D+D NA L + +P + +V+ LDRE + +Y
Sbjct: 312 NNPPGSHIYTVSASDSDINDNAPLFISDNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEY 371
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
+ + A+D G DVNDN+P F + + + +N +
Sbjct: 372 QVVITAKDEGSPSLSISMTINVEIS-DVNDNAPLFQQTADTIFIRE------NNPPGSQI 424
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN---------L 1227
++ + +N+ I T K + D L+L R+ Q +
Sbjct: 425 YIVSASDSDTGQNSFI-TYSLKSPSKDNK--SKSLVLVLNQALDREKQASHLLTLTAADC 481
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE--HY 1285
G P S T + + V DV D P F Y + I EN +V L T+
Sbjct: 482 GTPKRSGTTQIRILVQDVNDNA-----PTFRHPIYRVSIPENYAVGSLIVVLKATDLDEG 536
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER-QKYSREL 1344
EN + Y + +++ F I+ NG ++L D E K YE+ V+ R Q +
Sbjct: 537 ENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGI 596
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
P + T Y + + D+NDN P FT
Sbjct: 597 PAL----------STTAY---IYFSVDDINDNPPLFT 620
Score = 79.8 bits (188), Expect = 5e-13
Identities = 47/135 (34%), Positives = 73/135 (54%), Gaps = 11/135 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I A D D G A + Y + S ++ FS++ G L+ ++ D + Q F
Sbjct: 1893 IQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIETGVLYAQRSFDYE-----QVKEF 1947
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+Q+ AS NP+++ A + I + D NDNLP F + Y +SI EN+P +VL V ATD
Sbjct: 1948 QIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISENIPINSTVLTVNATD 2007
Query: 333 KDQGENGEFTYQLDD 347
+D+G N + +Y+L D
Sbjct: 2008 RDEGTNAQ-SYRLSD 2021
Score = 79.8 bits (188), Expect = 5e-13
Identities = 49/151 (32%), Positives = 76/151 (50%), Gaps = 11/151 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN PI +T++++NA D+D G N QI Y F S+ S ++L F IN G
Sbjct: 2319 ISENTPINSTVLRVNASDMDEGTNAQITYSF--------SRTSVNSLHASM-FSINPTSG 2369
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ L E+ ++ +++ A DGG + + V + DVND+ PVF K+ Y + E
Sbjct: 2370 EIKTNNLLNYEAIRDYEISVQAKDGGGFVAHSKILVEITDVNDNPPVFIKSAYTIYLPEN 2429
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ ++ A D D G NA + Y I S+
Sbjct: 2430 NLPGATIYRIHALDLDMGDNAKVIYSIYVSE 2460
Score = 78.6 bits (185), Expect = 1e-12
Identities = 53/175 (30%), Positives = 84/175 (48%), Gaps = 14/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+D G A + Y I + FS++ G L+ ++ D + Q F + VQ
Sbjct: 2226 VNATDRDEGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYE-----QHKEFAMHVQ 2280
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDKDQG 336
A P ++ A + I ++D NDN P+ N+SI EN P +VL+V A+D D+G
Sbjct: 2281 AKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVNASDMDEG 2340
Query: 337 ENGEFTYQLDDPK------GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + TY FSI+P SG ++ +L+ EA + V AK+
Sbjct: 2341 TNAQITYSFSRTSVNSLHASMFSINPTSG--EIKTNNLLNYEAIRDYEISVQAKD 2393
Score = 75.8 bits (178), Expect = 9e-12
Identities = 107/454 (23%), Positives = 187/454 (41%), Gaps = 75/454 (16%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
++A D D+G N I Y +E +I + + V Y IN G + + R + E+E
Sbjct: 1 VSASDSDTGQNSFITYSL-TESFI-------EGVPVSSYIAINPHAGEIRLTRPIT-EAE 51
Query: 1013 ---FRLNISALDGG------------NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
FRL + A D G ++ D+ R V+DVND+ PVF ++ Y ++ E
Sbjct: 52 GDAFRLFVVAEDHGEPAMTALTQIIISIKDSGFARTHVEDVNDNPPVFNQSVYQCSITEN 111
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY---FIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
++ K+ ATD D G+N +Y + P F + TG + V GELD E +
Sbjct: 112 APKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSN 171
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y + + A DN DVNDN+P+ L P ++ ++
Sbjct: 172 TYEVLIDALDN-------------VTVVDVNDNAPEMTVTSLSL----PVPEDATHGTIV 214
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ--------N 1226
+++ + + ++ +F + F G+ + ++ L + K + +
Sbjct: 215 AIIRVRDRDSGNNGKVNCYSSTPTLFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKD 274
Query: 1227 LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
G PSLS + + V V+DV D + P+F + I EN + +++ ++
Sbjct: 275 EGYPSLSVSMTINVEVSDVND-----NAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDI 329
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N +I ++N + V P++ + DRE K Y+V++
Sbjct: 330 NDNAPLFI-SDNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEYQVVI------------- 375
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
A+D + + V I DVNDN+P F
Sbjct: 376 ----TAKDEGSPSLSISMTINVEISDVNDNAPLF 405
Score = 67.7 bits (158), Expect = 2e-09
Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 36/323 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF------------L 120
G ++S + + I DVNDN PIF + Y + E G + +
Sbjct: 864 GSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKI 923
Query: 121 IAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHK 179
I I + + + +I + + D + I ++ D G +L S+
Sbjct: 924 IYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHDKEFQIGITARDHGSPSLSSN-- 981
Query: 180 PVLLLRKVLDYDAGD------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
L+ ++D+DA D KE V M+ ++ +L + A D+D G+ A + Y
Sbjct: 982 -TTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVNTTVL---SVDATDKDEGLNAQITY 1037
Query: 234 ELISGNDRKL----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+D +L F ++ +G + +++LD ++ ++ + ++A ++ AQ
Sbjct: 1038 SFSKTSDNQLHTGTFDINPTSGKITTKRDLDFES-----VQSYEIAIEA--MDGGGFVAQ 1090
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
+V IE++D NDN PE + + I E+ G + + D+D G NGE Q+
Sbjct: 1091 TKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGAA 1150
Query: 350 GAFSIDPRSGWLTVRNQTVLDRE 372
+ S + + + LDRE
Sbjct: 1151 PFQIVSSSSRYYRIITASFLDRE 1173
Score = 62.5 bits (145), Expect = 9e-08
Identities = 66/251 (26%), Positives = 112/251 (44%), Gaps = 36/251 (14%)
Query: 218 IHAIDQDLGVGATLRYE---LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D+G YE L+ LFSLD G ++++ ELD + ++NT+ +
Sbjct: 121 LFATDMDVGKNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYE-----KSNTYEV 175
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A L+N + ++D+NDN PE V ++ + E+ +G V + D+D
Sbjct: 176 LIDA--LDN----------VTVVDVNDNAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRD 223
Query: 335 QGENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAK-ETNPSVVG 392
G NG+ P F I+P SG ++ + LDRE S ++ + AK E PS+
Sbjct: 224 SGNNGKVNCYSSTPT-LFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSV 282
Query: 393 TFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
+ + ++ + NAPL + + D + + N V + D
Sbjct: 283 SMTINVEVS-----DVNDNAPLFQQS---SDTIFIRENN-----PPGSHIYTVSASDSDI 329
Query: 453 NDNNPVFVPSN 463
NDN P+F+ N
Sbjct: 330 NDNAPLFISDN 340
Score = 59.7 bits (138), Expect = 6e-07
Identities = 80/336 (23%), Positives = 135/336 (40%), Gaps = 39/336 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT--- 139
+ + + D NDN+P+F Y V+V E P I +T T
Sbjct: 1643 IRIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKN 1702
Query: 140 -----IFKDIRAFD----RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
IF A ++ N N + + V D G +S +L ++ D
Sbjct: 1703 NFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQSK-----VLIEITDV 1757
Query: 191 DAGDKEF-QLVIMAS---GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
+ F Q V AS ++ +L+ ++A D+D G+ A + Y S F L
Sbjct: 1758 NDNVPVFTQAVYKASISENSPVNTTVLY---VNATDKDEGINAQIVYSF-SKTSENSFHL 1813
Query: 247 DSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
DS G + + + LD E N + + A+ +P +++ + +++ D+NDN P
Sbjct: 1814 DSSTGRFYRIVTKSALDREKTALYN---ITIVATDKGSPQLSSRKFIRLDISDVNDNPPV 1870
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL------DDP-KGAFSIDPRS 358
F + EN G S+ ++ A+D D G+N + Y + D P FSI+ +
Sbjct: 1871 FMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIET 1930
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G L Q D E ++++ A + NP GT
Sbjct: 1931 GVLYA--QRSFDYEQVKEFQIQITASDGGNPVRSGT 1964
Score = 58.4 bits (135), Expect = 1e-06
Identities = 63/297 (21%), Positives = 123/297 (41%), Gaps = 28/297 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT-------VP 135
+ + + D NDN+P+F Y V++ E P +T V
Sbjct: 2190 IRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVS 2249
Query: 136 RGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
+I + + +++ V D+G+ +L S+ L++R + D
Sbjct: 2250 SYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSN--ATLIIRIIDQNDNAP 2307
Query: 195 K----EFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL----ISGNDRKLFSL 246
K + + ++ I+ +L ++A D D G A + Y ++ +FS+
Sbjct: 2308 KILYPSTENMSISENTPINSTVL---RVNASDMDEGTNAQITYSFSRTSVNSLHASMFSI 2364
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+ +G + L+ +A + + + VQA + A +++ +E+ D+NDN P F
Sbjct: 2365 NPTSGEIKTNNLLNYEAIRDYE-----ISVQAKDGGGFV--AHSKILVEITDVNDNPPVF 2417
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
Y I + EN G ++ ++ A D D G+N + Y + + FS+D +G L V
Sbjct: 2418 IKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSIYVSEKYFSVDLENGNLYV 2474
Score = 56.4 bits (130), Expect = 6e-06
Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 10/107 (9%)
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-- 347
AR +E D+NDN P F Y SI EN P G V ++ ATD D G+NGE +Y+
Sbjct: 85 ARTHVE--DVNDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLV 142
Query: 348 PK---GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
P+ FS+D +G + V+ + LD E ++ + + A + N +VV
Sbjct: 143 PERMLSLFSLDKYTGEVWVKGE--LDYEKSNTYEVLIDALD-NVTVV 186
Score = 50.0 bits (114), Expect = 5e-04
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + ++D NDN P + + S+ N + + + +V A D D G N + Y
Sbjct: 2289 LSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVNASDMDEGTNAQITYS 2348
Query: 499 LQRTS-NLTITSPFKINPNTGTV 520
RTS N S F INP +G +
Sbjct: 2349 FSRTSVNSLHASMFSINPTSGEI 2371
Score = 48.4 bits (110), Expect = 0.002
Identities = 69/313 (22%), Positives = 128/313 (40%), Gaps = 23/313 (7%)
Query: 86 YIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR-GLTIFKDI 144
++EDVNDN P+F + Y ++ E P G L+A + + V + G T ++
Sbjct: 88 HVEDVNDNPPVFNQSVYQCSITENAPKGT-----LVAKL---FATDMDVGKNGETSYEFS 139
Query: 145 RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL-LLRKVLDYDAGDKEFQLVIMA 203
+ + + D + V + + ++++ ++ L V D D ++ + +
Sbjct: 140 KLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNVTVVDVNDNAPEMTVTS 199
Query: 204 SGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD 260
+ ++ + I D+D G + + K+ S + SL + LD
Sbjct: 200 LSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLFKINPAFSGDFSLIVNSPLD 259
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
+ + Q + + A P + + +E+ D+NDN P F+ I I EN P
Sbjct: 260 REKKSEYQ-----VVITAKDEGYPSLSVSMTINVEVSDVNDNAPLFQQSSDTIFIRENNP 314
Query: 321 NGFSVLQVMATDKDQGENGE-FTYQLDDPKGAFSID-PRSGWLTVRNQTVLDREAHSSLR 378
G + V A+D D +N F + A + P+S V LDRE S +
Sbjct: 315 PGSHIYTVSASDSDINDNAPLFISDNSNSVSAMLVTAPKSAQPAV--DAPLDRENKSEYQ 372
Query: 379 MKVYAK-ETNPSV 390
+ + AK E +PS+
Sbjct: 373 VVITAKDEGSPSL 385
Score = 42.7 bits (96), Expect = 0.075
Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
S + VE+T D NDN PVF+ S Y + N G I ++ A+D D+G N V+Y +
Sbjct: 2401 SKILVEIT--DVNDNPPVFIKS-AYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSI 2456
>UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenopus
tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
Length = 3630
Score = 186 bits (452), Expect = 5e-45
Identities = 224/923 (24%), Positives = 368/923 (39%), Gaps = 107/923 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI-------GKVKAVDPDLGQNGMVLYDL 499
V + DANDN PVF +Y S+ NA V ++ V+A D D G+N V+Y +
Sbjct: 1781 VVVTDANDNAPVFT-EEVYTVSISENAPVNAIVLCNDNAPKIVQASDLDTGENSKVIYSV 1839
Query: 500 QRTSN--LTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVV 555
T+ ++S F IN TG + S E A+ V+A D PS + + +
Sbjct: 1840 FNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDN-GYPSHQSHKWKFI 1898
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS--YDLLHG 613
++++ + P P F + Y ++ N G S+ + D ++ Y + +
Sbjct: 1899 KLDIS--DVNDNP--PVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLIYSISNA 1954
Query: 614 YEEGVPFAVEE-RSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVND 671
E P R I ++L R P Y+ +A + V + DVND
Sbjct: 1955 NTEDFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQRTSKKMIGVEISDVND 2014
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ-DVTDDI 730
+ +K + + EN+ A+ H + N L N V+
Sbjct: 2015 NAPLFIKPTYDAFL---PENNLPGALIYSLHAKDLDVGDNAKVTYSILNTNTDFSVSSYF 2071
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+I I T PLDRE ++ + V+ F+ G G + I + D NDN P+F
Sbjct: 2072 SI----NIETGAPLDRETESIHEL-VLTAFDGGNPVQTGTAIIKIIVSDFNDNAPIFTQE 2126
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y + EN + + I + A D DEG+N+ Y K+ NT FI
Sbjct: 2127 VYTVSLNENIPVNSTILR---VSANDKDEGSNSQITYYFAASSKQAM----NT----FII 2175
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
DS+ E K L D + E ++ IM D H L
Sbjct: 2176 DSISGEVKTKENL-----DFEKIEREFQIQIMAKD-------------------HGSPSL 2211
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
N + I V + + ++ + I ENIPI +TI+ ++A D D G+N QIRY F
Sbjct: 2212 NSSTNLRICIVDFNDNLPVFSQEVYKVS-INENIPINSTILYVSANDKDEGINSQIRYYF 2270
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDN 1028
S + ++ F+IN G ++ +L E + +++ A D
Sbjct: 2271 -----------STSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQANDQYTGETG 2319
Query: 1029 IS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+ +R+ V D ND+FP+F + Y ++ E + V A+D D G N+ LTY +
Sbjct: 2320 TALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSA 2379
Query: 1088 DTDL--PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
F I+P +G + + LDRE + Y +T+ A D G D+N
Sbjct: 2380 SKQATNAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKG-SPPLSSRKTIRLDVSDIN 2438
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DN+P F ++ +N S+ I EENA + + +
Sbjct: 2439 DNAPVFEKSTYIVYISE------NNEPGASIYSIQASDKDSEENAKLVYSSITSNREENL 2492
Query: 1206 FIGNGNGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKP 1255
I + ++ +P + +++ G P + TA++ +TV D+ D P
Sbjct: 2493 RIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNF-----P 2547
Query: 1256 VFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNG 1313
+F Y + I EN+ N+ V VS N + N ++ Y + R+F I+ G
Sbjct: 2548 IFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQIT-YSFSATSKQASRSFSINSETG 2606
Query: 1314 TLYLVRSPDREVKDTYEVIVRAE 1336
+ + D E YE+ V+A+
Sbjct: 2607 EIKTKENLDFEKTKNYEISVQAK 2629
Score = 161 bits (391), Expect = 1e-37
Identities = 228/940 (24%), Positives = 382/940 (40%), Gaps = 138/940 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + DANDN PVF +Y+ S+ N + + + +V A D D G N + Y RTS
Sbjct: 1355 IRVIVTDANDNTPVFT-QEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSV 1413
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
++ + V E P+ ++ H L + ASD + R A++ + VT
Sbjct: 1414 NSLHAKL----------VLERPLDREIKNIHELLLTASD---GGTPVRTGTALIRVIVTD 1460
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV- 618
+ P F Y+ + N I ++V ++ +D E + ++Y E +
Sbjct: 1461 A----NDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLH 1516
Query: 619 --PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVNDERGV 675
F++ SG I L R + +++ A + T V V D ND V
Sbjct: 1517 ASMFSINPTSGEIKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPV 1576
Query: 676 LLKGAHS-PIIFHVKENSAGAAIG---QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + I + NS + TN Y +V L A+ +
Sbjct: 1577 FTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSIN---- 1632
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I T+KPLDRE + + + + A + G G + I + D NDN PVF
Sbjct: 1633 -PTSGEITTKKPLDREAQTSHELILTAS-DGGNPVRTGTALIQIIVTDANDNLPVFTEVL 1690
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y I EN+ +G +++ +A + + F ++ TGV+ +
Sbjct: 1691 YTVSISENTAVG------SVVLCVNASSNAKITYSISETNTMSPYFSINIETGVL-YAQQ 1743
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELII------MIGDENDNKPEFNQIEENSKVR 903
S D E+ +++ ++A+D G ++S L+I ++ D NDN P F EE V
Sbjct: 1744 SFDYEQHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFT--EEVYTVS 1801
Query: 904 IHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
I +N + L +N P I++ A DLD+G N
Sbjct: 1802 ISENAPVNA------------------------IVLCNDNAP---KIVQ--ASDLDTGEN 1832
Query: 964 GQIRYE-FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISAL 1020
++ Y FN+ + +A V YF IN G + RS E EF +++ A
Sbjct: 1833 SKVIYSVFNT---------NTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAK 1883
Query: 1021 DGGNLNDNISVRVFVK----DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
D G + F+K DVND+ PVF+K+ Y + E + V ATD D G
Sbjct: 1884 DNGYPSHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGD 1943
Query: 1077 NANLTYFIQPSDTDLPFEISPLTG----VLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
NA L Y I ++T+ F + TG +++ N LDRE Y +T++A D G
Sbjct: 1944 NAKLIYSISNANTE-DFPLISSTGRFYRIVTTN-NLDRERTPFYNITILATDRG-YPQRT 2000
Query: 1133 XXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE-LSNHNFESVMMIPVYKATIEENAP 1191
DVNDN+P F P D L +N ++ ++ ++
Sbjct: 2001 SKKMIGVEISDVNDNAPLFI---------KPTYDAFLPENNLPGALIYSLHAKDLDVGDN 2051
Query: 1192 IGTTVAKVFANDTDF-IGNGNGL-ILYSLPQRKNQQNL----------GLPSLSSTAILM 1239
T + + +TDF + + + I P + +++ G P + TAI+
Sbjct: 2052 AKVTYS-ILNTNTDFSVSSYFSINIETGAPLDRETESIHELVLTAFDGGNPVQTGTAIIK 2110
Query: 1240 VTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNE 1297
+ V+D D + P+F Y + + EN VN+ + VS N + N ++ YY
Sbjct: 2111 IIVSDFND-----NAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFA-A 2164
Query: 1298 NDTDIRRTFVIDPRNGTLYLVRSPDRE-VKDTYEVIVRAE 1336
+ TF+ID +G + + D E ++ +++ + A+
Sbjct: 2165 SSKQAMNTFIIDSISGEVKTKENLDFEKIEREFQIQIMAK 2204
Score = 159 bits (387), Expect = 4e-37
Identities = 226/987 (22%), Positives = 401/987 (40%), Gaps = 119/987 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + ++D NDN P ++L + ++ GTVI +K D D G+NG V + +
Sbjct: 246 VLIEIIDENDNAPEISIASL-SAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGAAP 304
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
I S T S + + + + + A+D+ + S+ + +V
Sbjct: 305 FQIVSSSSRYYRIITASFLDREKVPW-YNITILATDKGSPELSSTKSIKIAITDVN---- 359
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVP--- 619
IP F Y+ + ++ I T+V Q+ D E ++Y L+ + +
Sbjct: 360 ---DHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASAT 416
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F++ SG I +L+ + Y+ A ++ ++ + + DVND + LK
Sbjct: 417 FSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKSYIKKVIR---LDISDVNDNPPLFLKS 473
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA------ 733
+ + ++ EN+ A I+ S + V + I+N T+D A++
Sbjct: 474 TY---VAYLPENNIPGA--SIYKIQASDLDLGDNAKVIYSISNSN--TEDFAVSSFFSIN 526
Query: 734 -EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E G +++Q+ D E+ V++M ++A I + D NDN PVF Y
Sbjct: 527 IETGVLYSQRSFDYEQHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVFTQQVY 586
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFDVDENTGVVK 847
+ I E++ I + + ++ ATD D+GTN Y+ + +MF+++ G +K
Sbjct: 587 KISISESAPINSTV---TVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIK 643
Query: 848 --FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN-QIEENSKVRI 904
DS + + ++++ TG + + M +++ K + +++N +
Sbjct: 644 TKVDADSGHNSWLSYHFIQIISQHTGEIRTSR----MFQEKDILKHKVVIMVKDNGDPSL 699
Query: 905 HRETKLNGTAGFTIIEVKPK--NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
L+ G V P+ N+F + EN PI +T+I L A D D G
Sbjct: 700 SATVTLSLAVGDHFQHVVPQINNEFNDGPSSKVYKVSVSENAPINSTVIILTATDKDEGT 759
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISAL 1020
N +I Y SK S + ++ I+ +G++++ L E S L ++A
Sbjct: 760 NAKITYSI--------SKTSKN-----NFYTIDLDNGNLVLENPLDREMQSTHELTLTAF 806
Query: 1021 DGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
DGG +++ V DVND+ PVF + Y ++ E + V+ATD D G NA
Sbjct: 807 DGGTPVRTGTALIKITVTDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINA 866
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
+ Y S+ F I +G+L V LDRET+ + L + A D G
Sbjct: 867 QIVYSFSVSEK--YFSIDLQSGMLYVKKPLDRETQTIHELILTASDGG-NPVRSGTALIR 923
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK 1198
D NDN P F E+ + E +++ +V+ + NA I + +K
Sbjct: 924 IAVTDSNDNLPVF--TQEVYKVSISENIPINS----TVLTVNATDRDEGTNAQIMYSFSK 977
Query: 1199 VFANDTDFIGNGNGLILYSLPQRKNQQNL-----------------GLPSLSSTAILMVT 1241
N+ + I Y+ + K +QN G PSLS A L +
Sbjct: 978 TSGNN---LHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTIR 1034
Query: 1242 VADVPDEVEMSDKP---VFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
+ D D V P S + + + A + V + N + Y+++ +
Sbjct: 1035 ITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGS 1094
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEG 1358
+ + F I G + RS DRE Y + ++A R PH+
Sbjct: 1095 EPSL---FSISQNTGEIRTSRSLDREKVPWYNITIQAT----DRGSPHL----------- 1136
Query: 1359 MTKYDVKVV-VRIKDVNDNSPKFTNGN 1384
++K++ + I DVNDN+P FT +
Sbjct: 1137 ---SNIKLIKLDISDVNDNAPVFTKSS 1160
Score = 151 bits (367), Expect = 1e-34
Identities = 183/726 (25%), Positives = 322/726 (44%), Gaps = 89/726 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++T+ D NDN PVF +Y+ + ++ +GTV+ ++ D D G+NG V+ +
Sbjct: 2970 IKITVTDVNDNFPVFT-QEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVI------CH 3022
Query: 505 LTITSPFKINPNTGTV-SVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ PFK+ ++G + + L+ + + ++A+D+ + P + ++ + ++
Sbjct: 3023 IVGMVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDI 3082
Query: 560 TRGTKGNKPDIPDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEE 616
+ P F + Y + V + GT V ++ DA ++ +SY L E
Sbjct: 3083 N-------DNAPVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSET 3135
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F +++ +G I L R + + E + + + T T+ + V D L
Sbjct: 3136 S-HFIIDQYTGEIRTSTSLDRETQSNH--ELILTASDGGNPVQTGTTLIKITVTDFNDNL 3192
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDDIAI-AE 734
+ ++ EN IFH N S + + ++ +V +I +
Sbjct: 3193 PEFTQEVYKVNIHENIP--LNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPK 3250
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHATY 792
+G I T+ LD+EK Y +T+ A +KG S YQ TI ++ D NDN PVFE + Y
Sbjct: 3251 NGAIKTKGTLDKEKNSHYNITIQAT-DKG--SPPLSYQKTIRLDVLDINDNSPVFEKSQY 3307
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
++ EN++ G I I+A D D N +Y++ E + +I S
Sbjct: 3308 IAYVPENNQPGASIFS---IQAIDKDTEENGKLLYSIITRNTEEMPS------ISYI--S 3356
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
++ ++Y A+ + + E I I +++ P N ++ VRI T +
Sbjct: 3357 INPVTGVIY-----AQRSFDYEQDREFKIQIMAKDNGSPPLNS---SAIVRI---TVTDF 3405
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
F + F +V ++ I ENIPI +T++ +NA D D G+N QI Y F
Sbjct: 3406 NDNFPV--------FTQEVYKVN----IHENIPINSTVLHVNASDKDEGINAQITYSF-- 3451
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDN 1028
S SA+ L R F IN ++G + + +L E S + + I A D G+ L+
Sbjct: 3452 ------STTSANVL---RMFYINPQNGEIKIKGTLDRERSSHYNITIQATDKGSPPLSSW 3502
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
++ + V D+ND+ PVF+K+ Y V E + + A D D +N L Y I S+
Sbjct: 3503 KTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEENGKLFYSIITSN 3562
Query: 1089 TD-----LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
T+ I+P+TGV+ D E + ++ + ++A+DNG D
Sbjct: 3563 TEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQIIAKDNG-SPPLNSSTIVRICVVD 3621
Query: 1144 VNDNSP 1149
NDNSP
Sbjct: 3622 QNDNSP 3627
Score = 151 bits (366), Expect = 1e-34
Identities = 222/947 (23%), Positives = 386/947 (40%), Gaps = 100/947 (10%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y D + + + + ++ DANDN P F +Y+ M N V T + V A D D G N
Sbjct: 129 KYLDRETQTLIKIIIS--DANDNIPEF-SKEVYKVKMSENTPVNTTVLSVDATDKDEGLN 185
Query: 493 GMVLYDLQRTS-NLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERR 549
+ Y +TS N T F INP +G ++ E + + +EA D ++ +
Sbjct: 186 AQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTK 245
Query: 550 YSLAVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDV 606
V IE+ N P+I + AP + + GT + I+V+ D +V
Sbjct: 246 -----VLIEII-DENDNAPEISIASLSAP----IPEDSMPGTVIALIKVHDQDTGRNGEV 295
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVH 665
+L + + +IT L R P Y+ +A + + LS + +
Sbjct: 296 DCQILGAAPFQIVSSSSRYYRIIT-ASFLDREKVPWYNITILATDKGSPELSSTKSIKIA 354
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
+ DVND + + + I + + Q+ T+ G LI D
Sbjct: 355 ITDVNDHIPMFTQEVYKVSI--SESIPINTTVLQVNATDKDE--GVNAQITYSLIRTSGD 410
Query: 726 VTDDIAIA---EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ G I T++ L+ E + Y M+V A+ +K I + + I D ND
Sbjct: 411 SLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAK-DKSYIKKV----IRLDISDVND 465
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE------M 836
NPP+F +TY ++ EN+ G I I+A+D D G NA +Y++ E
Sbjct: 466 NPPLFLKSTYVAYLPENNIPGASIYK---IQASDLDLGDNAKVIYSISNSNTEDFAVSSF 522
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAEL-IIMIGDENDNKPEF 893
F ++ TGV+ + S D E+ ++++ ++ARD G LS+ A L +I++ D NDN P F
Sbjct: 523 FSINIETGVL-YSQRSFDYEQHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVF 581
Query: 894 NQIEENSKVRIHRETKLNGTAGFTIIEVKPKN-------KFALDVDQLGPLFLIPENIPI 946
Q + K+ I +N T T++ K+ ++ NI
Sbjct: 582 TQ--QVYKISISESAPINSTV--TVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINP 637
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR- 1005
IK +D DSG N + Y F + ++ + ++ + +H VI+ +
Sbjct: 638 ANGEIK-TKVDADSGHNSWLSYHFIQIISQHTGEIRTSRMFQEKDIL---KHKVVIMVKD 693
Query: 1006 SLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKT-WYNFNVEEAQYTRRVL 1064
+ P + +S G + V +N+ F + Y +V E +
Sbjct: 694 NGDPSLSATVTLSLAVGDHFQH------VVPQINNEFNDGPSSKVYKVSVSENAPINSTV 747
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+ ATD D G NA +TY I + + + I G L + LDRE + + LT+ A D
Sbjct: 748 IILTATDKDEGTNAKITYSISKTSKNNFYTIDLDNGNLVLENPLDREMQSTHELTLTAFD 807
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA 1184
G DVNDN P F + + +A N + ++ Y
Sbjct: 808 GG-TPVRTGTALIKITVTDVNDNVP---VFTQAVY----KASISENSPVNTTVL---YVN 856
Query: 1185 TIEENAPIGTTVAKVFANDTDF--IGNGNGLILYSLPQRKNQQNL----------GLPSL 1232
+++ I + F+ + I +G++ P + Q + G P
Sbjct: 857 ATDKDEGINAQIVYSFSVSEKYFSIDLQSGMLYVKKPLDRETQTIHELILTASDGGNPVR 916
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKM 1290
S TA++ + V D D + PVF Y++ I EN+ ++++N T+ E N ++
Sbjct: 917 SGTALIRIAVTDSNDNL-----PVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQI 971
Query: 1291 RYYILNENDTDIRRT-FVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
Y + ++ + F I+ +G + ++ + E K YE+ V A+
Sbjct: 972 MYSFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVYAK 1018
Score = 144 bits (348), Expect = 2e-32
Identities = 143/563 (25%), Positives = 247/563 (43%), Gaps = 40/563 (7%)
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
T+ + D++ S+ ++ Y ++ + TF + + + N EK F
Sbjct: 2141 TILRVSANDKDEGSNSQITYYFAASSKQAMNTFIIDSISGEVKTKE---NLDFEKIEREF 2197
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
++ K ++ L S N+ + ++D NDN PVF +Y+ S+ N + + I
Sbjct: 2198 QIQIMAK----DHGSPSLNSSTNLRICIVDFNDNLPVF-SQEVYKVSINENIPINSTILY 2252
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEAS 539
V A D D G N + Y TS+ I + F IN +G + E+ E + + V+A+
Sbjct: 2253 VSANDKDEGINSQIRYYFS-TSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQAN 2311
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
DQ + A++ I VT + P F Y+ + N+ + ++V + +D
Sbjct: 2312 DQYTGET----GTALIRITVTDAND----NFPMFSQEIYKVSINENMPLNSTVLYVSASD 2363
Query: 600 AFE--QNDVSYDLLHGYEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN- 655
E + ++Y ++ FA+ +SG I L R + YD A + +
Sbjct: 2364 KDEGINSQLTYSFSSASKQATNAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPP 2423
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
LS + V D+ND V K + I++ + N GA+I I ++ S
Sbjct: 2424 LSSRKTIRLDVSDINDNAPVFEKSTY--IVYISENNEPGASIYSIQASDKDSEENAKLVY 2481
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
++++ D I+E + + PL+RE ++ + V+ F+ G G + I
Sbjct: 2482 SSITSNREENLRIDSDISE---LVLEIPLNRETESIHEI-VLTAFDGGSPMQTGTALIRI 2537
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ D NDN P+F Y I EN + + + + A D D+G N+ Y+ K+
Sbjct: 2538 TVTDMNDNFPIFGQEVYTVSINENIPLNSTVLC---VSANDKDQGINSQITYSFSATSKQ 2594
Query: 836 M---FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI--GDENDNK 890
F ++ TG +K ++LD EK Y++S+ A+D GGL S A++ I I D NDN
Sbjct: 2595 ASRSFSINSETGEIK-TKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNF 2653
Query: 891 PEFNQIEENSKVRIHRETKLNGT 913
P F Q E KV IH ++ T
Sbjct: 2654 PVFTQ--EVYKVNIHENIPIHST 2674
Score = 140 bits (340), Expect = 2e-31
Identities = 202/880 (22%), Positives = 361/880 (41%), Gaps = 76/880 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G ++S+ S+ + I DVND++P+F Y V++ E P + +
Sbjct: 341 GSPELSSTKSIKIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQI 400
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYD 191
T + D A N + ++ ++ H+ + K ++KV+ D
Sbjct: 401 TYSL-IRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKSYIKKVIRLD 459
Query: 192 AGDKEFQ--LVIMASGKRIHKEILFPEP----IHAIDQDLGVGATLRYELISGNDR---- 241
D L + ++ E P I A D DLG A + Y + + N
Sbjct: 460 ISDVNDNPPLFLKSTYVAYLPENNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAV 519
Query: 242 -KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV-EIELLDL 299
FS++ G L+ ++ D + Q F +++ A +P + A + I + D
Sbjct: 520 SSFFSINIETGVLYSQRSFDYE-----QHKVFQMEIMARDGGSPPLSNNATLFMIIVTDY 574
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGA-----FS 353
NDN+P F Y ISI E+ P +V V ATDKD G NG TY + A F+
Sbjct: 575 NDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFN 634
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP 413
I+P +G + +T +D ++ + + + + G S+ + + L+
Sbjct: 635 INPANGEI----KTKVDADSGHNSWLSYHFIQIISQHTGEIRTSRMFQE--KDILKHKVV 688
Query: 414 LEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA 473
+ P T T ++ D F +V + + ++ P S +Y+ S+ NA
Sbjct: 689 IMVKDNGDPSLSATVTLSLAVGDH----FQHVVPQINNEFNDGP---SSKVYKVSVSENA 741
Query: 474 KVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEG 530
+ + + + A D D G N + Y + +TS + + I+ + G + V E+P+ ++
Sbjct: 742 PINSTVIILTATDKDEGTNAKITYSISKTSK---NNFYTIDLDNGNL-VLENPLDREMQS 797
Query: 531 RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGT 590
H L + A D + R A++ I VT ++P F A Y+ + N + T
Sbjct: 798 THELTLTAFD---GGTPVRTGTALIKITVT----DVNDNVPVFTQAVYKASISENSPVNT 850
Query: 591 SVGQIRVNDAFEQNDVSYDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVA 649
+V + VN + ++ +++ + F+++ +SG++ V L R + +++ A
Sbjct: 851 TV--LYVNATDKDEGINAQIVYSFSVSEKYFSIDLQSGMLYVKKPLDRETQTIHELILTA 908
Query: 650 LQ-ENANLSIVTNATVHVVDVNDERGVLLKGAHS-PIIFHVKENSAGAAIGQIFH---TN 704
N S + V D ND V + + I ++ NS + TN
Sbjct: 909 SDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTN 968
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
+Y + L + + G I T++ + E + Y ++V A+ + G
Sbjct: 969 AQIMYSFSKTSGNNLHTSMFSIN-----YTSGEIKTKQNFNFEAKKFYEISVYAK-DYGS 1022
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK---ATDADEGT 821
S + +TI I D+NDN P + + E + + +I A DAD G
Sbjct: 1023 PSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGH 1082
Query: 822 NALFMY-TLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAE 878
NA Y + G +F + +NTG ++ SLDREK Y +++ A D G LS+
Sbjct: 1083 NAWLSYHVVQGSEPSLFSISQNTGEIR-TSRSLDREKVPWYNITIQATDRGSPHLSNIKL 1141
Query: 879 LIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTI 918
+ + I D NDN P F ++S V E L G + + I
Sbjct: 1142 IKLDISDVNDNAPVFT---KSSYVAYIAENNLAGASIYRI 1178
Score = 134 bits (325), Expect = 1e-29
Identities = 132/484 (27%), Positives = 215/484 (44%), Gaps = 37/484 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++T+ D NDN PVF + +Y+ S+ N+ V T + V A D D G N ++Y +
Sbjct: 819 IKITVTDVNDNVPVFTQA-VYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSVSEK 877
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I+ +G + V + E + H L + ASD NP R A++ I VT
Sbjct: 878 Y-----FSIDLQSGMLYVKKPLDRETQTIHELILTASDG-GNPV--RSGTALIRIAVT-- 927
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV----SYDLLHGYEEGV 618
+ ++P F Y+ + N+ I ++V + D E + S+ G
Sbjct: 928 --DSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHT 985
Query: 619 P-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F++ SG I + + + Y+ A + +LS + T+ + D ND +
Sbjct: 986 SMFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTIRITDQNDNVPKI 1045
Query: 677 L----KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L + S + GA I ++ + S G+ ++ + I+
Sbjct: 1046 LYPSSESVDSSFEMVPVASEQGALITKVVAVDADS--GHNAWLSYHVVQGSEPSLFSIS- 1102
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G I T + LDREK Y +T+ A ++G + I + + I D NDN PVF ++Y
Sbjct: 1103 QNTGEIRTSRSLDREKVPWYNITIQAT-DRGSPHLSNIKLIKLDISDVNDNAPVFTKSSY 1161
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY-TLFGEGKEMFDVDENTGVVKFIGD 851
+I EN+ G I I+A+D D G NA Y + G +F + +NTG ++
Sbjct: 1162 VAYIAENNLAGASIYR---IQASDIDAGDNAKLSYHVVQGSEPSLFSISQNTGEIRTSQK 1218
Query: 852 SLDREKKIMYKLSLVARDTGG-LSSEAELI-IMIGDENDNKPEFNQIEENSKVRIHRETK 909
LDRE + +++L L A D G L + LI I++ D NDN P F Q E KV I
Sbjct: 1219 PLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQ--EVYKVSISENAP 1276
Query: 910 LNGT 913
+N +
Sbjct: 1277 INSS 1280
Score = 132 bits (319), Expect = 7e-29
Identities = 130/482 (26%), Positives = 209/482 (43%), Gaps = 29/482 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + D+NDN PVF +Y+ S+ N + + + V A D D G N ++Y +TS
Sbjct: 922 IRIAVTDSNDNLPVFT-QEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSG 980
Query: 505 LTI-TSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSL-AVVTIEVTRG 562
+ TS F IN +G + ++ E + F E S + S A +TI +T
Sbjct: 981 NNLHTSMFSINYTSGEIKTKQNFNFEAKK--FYEISVYAKDYGSPSLSCNASLTIRIT-D 1037
Query: 563 TKGNKPDI--PDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG 617
N P I P F V G + ++ DA ++ +SY ++ G E
Sbjct: 1038 QNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPS 1097
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
+ F++ + +G I L R P Y+ A + +LS + + + DVND V
Sbjct: 1098 L-FSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVF 1156
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K ++ + + + N AGA+I +I S I + + + + + G
Sbjct: 1157 TKSSY--VAYIAENNLAGASIYRI---QASDIDAGDNAKLSYHVVQGSEPSLFSISQNTG 1211
Query: 737 TIFT-QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
I T QKPLDRE + ++ + + A + G G + I + D NDN PVF Y+
Sbjct: 1212 EIRTSQKPLDRETQSIHELILTAS-DGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVS 1270
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF--DVDENTGVVKFIGDSL 853
I EN+ I + + I+ ATD DEGTNA Y++ + F V V+ I +
Sbjct: 1271 ISENAPINSSV---IILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKV 1327
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
++ A D G + A + +++ D NDN P F Q E KV I T +N
Sbjct: 1328 STSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ--EVYKVSISENTPIN 1385
Query: 912 GT 913
T
Sbjct: 1386 ST 1387
Score = 124 bits (298), Expect = 2e-26
Identities = 142/518 (27%), Positives = 222/518 (42%), Gaps = 39/518 (7%)
Query: 411 NAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMK 470
N E+T Y + + ++ + L S + + +LD NDN P F SN + +
Sbjct: 2720 NVDFEETKYY---DISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTE 2776
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDL---QRTSNLTITSPFKINPNTGTVSVAESPI 527
+N + G I ++A+D D +NG V+Y + TS + F INPN G ++ +
Sbjct: 2777 NN-QPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVD 2835
Query: 528 LE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + + VEA D + S + V I+ N P F + Y +V N
Sbjct: 2836 FEEVKYYDISVEAQDGGSLVSHSK-----VLIQNVSDINDNP---PKFEKSNYVAYVTEN 2887
Query: 586 VGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEE--GVPF-AVEERSGVITVVDDLSRYNR 640
G+S+ I+ D E V Y + + E V + ++ +G +T L R +
Sbjct: 2888 NQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQ 2947
Query: 641 PMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
++ A N + T + V DVND V + + + ++++ G +
Sbjct: 2948 SNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPV--SEDSTLGTVVAL 3005
Query: 700 IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
I ++ S G V I + I T LDREK Y +T+ A
Sbjct: 3006 IEGHDLDS---GENGEVICHIVGMVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQAT 3062
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE-GFIMENSKIGTEIKMDNIIKATDAD 818
+KG + + + I D NDN PVFE +TY + +S+ GT + + A DAD
Sbjct: 3063 -DKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQGTLVTK---VVAVDAD 3118
Query: 819 EGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG-LSSE 876
G NA Y + + F +D+ TG ++ SLDRE + ++L L A D G + +
Sbjct: 3119 SGHNAWLSYHFLQDSETSHFIIDQYTGEIR-TSTSLDRETQSNHELILTASDGGNPVQTG 3177
Query: 877 AELI-IMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
LI I + D NDN PEF Q E KV IH LN T
Sbjct: 3178 TTLIKITVTDFNDNLPEFTQ--EVYKVNIHENIPLNST 3213
Score = 120 bits (288), Expect = 4e-25
Identities = 184/754 (24%), Positives = 321/754 (42%), Gaps = 103/754 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D+G A + Y +++ N FS+ S S+ +E LD E + L +
Sbjct: 2041 LHAKDLDVGDNAKVTYSILNTNTD--FSVSSYF-SINIETGAPLDRETE---SIHELVLT 2094
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A NP++T A ++I + D NDN P F + Y +S+ EN+P ++L+V A DKD+G
Sbjct: 2095 AFDGGNPVQTGTAIIKIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGS 2154
Query: 338 NGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKE-TNPSV- 390
N + TY F ID SG V+ + LD E ++++ AK+ +PS+
Sbjct: 2155 NSQITYYFAASSKQAMNTFIIDSISG--EVKTKENLDFEKIEREFQIQIMAKDHGSPSLN 2212
Query: 391 --------VGTFADSQRIAKWR--RQPLETNAPLEKT-TYVFP-DKVGTKTENIEYY--- 435
+ F D+ + + + N P+ T YV DK I YY
Sbjct: 2213 SSTNLRICIVDFNDNLPVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFST 2272
Query: 436 -DEQLM-SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN----AKVGTVIGKVKAVD--- 486
+Q++ +F+ ++ N F + LYE S+++N + GT + ++ D
Sbjct: 2273 SSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQANDQYTGETGTALIRITVTDAND 2332
Query: 487 --PDLGQ-------------NGMVLY------DLQRTSNLTIT---------SPFKINPN 516
P Q N VLY D S LT + + F INP
Sbjct: 2333 NFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAINPQ 2392
Query: 517 TGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
+G + V S + ++ + + ++A+D+ + P R ++ + ++ + P F
Sbjct: 2393 SGEI-VTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDVSDI-------NDNAPVF 2444
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND---VSYDLLHGYEEGVPFAVEERSGVIT 630
+ Y ++ N G S+ I+ +D + + V + EE + ++ +
Sbjct: 2445 EKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYSSITSNREENL--RIDSDISELV 2502
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVNDERGVLLKGAHSPIIFHVK 689
+ L+R +++ A + + T + V D+ND + + ++ +
Sbjct: 2503 LEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYT---VSIN 2559
Query: 690 ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKR 749
EN + N N F ++Q +E G I T++ LD EK
Sbjct: 2560 ENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKT 2619
Query: 750 DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
Y ++V A+ G++S A I + I + D NDN PVF Y+ I EN I + +
Sbjct: 2620 KNYEISVQAKDGGGLVSHAKI-NIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQ- 2677
Query: 810 NIIKATDADEGTNALFMYTLFGEGK----EMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ A+D DEG NA Y+ FG +F ++ +G + G ++D E+ Y +S+
Sbjct: 2678 --VNASDKDEGINAQITYS-FGTTATNVLRIFAINPKSGEITTKG-NVDFEETKYYDISV 2733
Query: 866 VARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
A+D + LSS + + I D NDN P+F +
Sbjct: 2734 QAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEK 2767
Score = 119 bits (287), Expect = 5e-25
Identities = 116/465 (24%), Positives = 208/465 (44%), Gaps = 37/465 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT-S 503
+ V + D NDN P+F+ Y+ + N G +I + A D D+G N V Y + T +
Sbjct: 2005 IGVEISDVNDNAPLFIKPT-YDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYSILNTNT 2063
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ +++S F IN TG E+ E H L + A D NP + A++ I V+
Sbjct: 2064 DFSVSSYFSINIETGAPLDRET---ESIHELVLTAFD-GGNPVQT--GTAIIKIIVS--- 2114
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV-PF 620
+ P F Y + N+ + +++ ++ ND E + ++Y ++ + F
Sbjct: 2115 -DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTF 2173
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQE---NANLSIVTNATVHVVDVNDERGVLL 677
++ SG + ++L + + +F+ + + + +L+ TN + +VD ND V
Sbjct: 2174 IIDSISGEVKTKENLD-FEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVF- 2231
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR--FLIANQQDVTDDIAIAED 735
S ++ V N I + + + +R F +++Q + I +
Sbjct: 2232 ----SQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSIS 2287
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T++ LD EK +Y ++V A N G + I + D NDN P+F Y+
Sbjct: 2288 GAIMTKENLDFEKTKLYEISVQA--NDQYTGETGTALIRITVTDANDNFPMFSQEIYKVS 2345
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE---MFDVDENTGVVKFIGDS 852
I EN + + + + A+D DEG N+ Y+ K+ F ++ +G + +
Sbjct: 2346 INENMPLNSTVL---YVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSGEI-VTSST 2401
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
LDRE K Y +++ A D G LSS + + + D NDN P F +
Sbjct: 2402 LDREMKSHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVFEK 2446
Score = 118 bits (283), Expect = 2e-24
Identities = 124/438 (28%), Positives = 188/438 (42%), Gaps = 52/438 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN PI +T++++NA D+D G N QI Y F S+ S ++L F IN G
Sbjct: 1477 ISENTPINSTVLRVNASDMDEGTNAQITYSF--------SRTSENSLHASM-FSINPTSG 1527
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ R L E++ L ++A DGG +RV V D ND+ PVF + Y ++
Sbjct: 1528 EIKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSIS 1587
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEISPLTGVLSVNGELDRE 1111
E + +V+A+D D G NA +TY F + S L F I+P +G ++ LDRE
Sbjct: 1588 ENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDRE 1647
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+ + L + A D G D NDN P F E+L N
Sbjct: 1648 AQTSHELILTASDGG-NPVRTGTALIQIIVTDANDNLP---VFTEVLY----TVSISENT 1699
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY---SLPQRKNQQ--- 1225
SV++ NA I ++++ F N +LY S +++Q
Sbjct: 1700 AVGSVVLC----VNASSNAKITYSISETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEM 1755
Query: 1226 -----NLGLPSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELEIEEN--VNAPV--- 1274
+ G PS++S L++ + D + +D PVF Y + I EN VNA V
Sbjct: 1756 EIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCN 1815
Query: 1275 ----ELVSLNLTEHYENFKMRYYILNENDT--DIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
++V + + EN K+ Y + N N + F I+ G LY RS D E
Sbjct: 1816 DNAPKIVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKE 1875
Query: 1329 YEVIVRAERQKYSRELPH 1346
+ + V+A+ Y H
Sbjct: 1876 FAMHVQAKDNGYPSHQSH 1893
Score = 117 bits (281), Expect = 3e-24
Identities = 108/413 (26%), Positives = 176/413 (42%), Gaps = 35/413 (8%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++P + GT + K+ A+D DSG N + Y F + S+ S +F+I++
Sbjct: 3098 MVPFSSEQGTLVTKVVAVDADSGHNAWLSYHF-----LQDSETS--------HFIIDQYT 3144
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + SL E S L ++A DGGN +++ V D ND+ P F + Y N+
Sbjct: 3145 GEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVNI 3204
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP-FEISPLTGVLSVNGELDRET 1112
E + V+A+D D G NA +TY F S+ L F I P G + G LD+E
Sbjct: 3205 HENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGAIKTKGTLDKEK 3264
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL---EWKHPEADELS 1169
Y +T+ A D G D+NDNSP F + E P A S
Sbjct: 3265 NSHYNITIQATDKGSPPLSYQKTIRLDVL-DINDNSPVFEKSQYIAYVPENNQPGASIFS 3323
Query: 1170 NHNFESVMMI--PVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
+ + + I N +++ + N + Y + Q +
Sbjct: 3324 IQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDYEQDREFKIQIM 3383
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
G P L+S+AI+ +TV D D PVF Y++ I EN+ ++ +N ++
Sbjct: 3384 AKDNGSPPLNSSAIVRITVTDFNDNF-----PVFTQEVYKVNIHENIPINSTVLHVNASD 3438
Query: 1284 HYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
E + Y + ++ R F I+P+NG + + + DRE Y + ++A
Sbjct: 3439 KDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQA 3491
Score = 116 bits (278), Expect = 7e-24
Identities = 181/721 (25%), Positives = 291/721 (40%), Gaps = 88/721 (12%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL-QRTSNLTITS 509
D NDN P F SN + ++N + G+ I +KA+D D +NG V+Y + T + S
Sbjct: 2867 DINDNPPKFEKSNYVAYVTENN-QPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVS 2925
Query: 510 PFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
INP TG V+ S E H L + ASD NP + +L +T+ T N
Sbjct: 2926 YISINPVTGFVTNQTSLDRETQSNHELILTASD-GGNPVQTGTTLIKITV-----TDVN- 2978
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
+ P F Y+ V + +GT V I +D + + + H VPF + SG
Sbjct: 2979 DNFPVFTQEVYKTPVSEDSTLGTVVALIEGHD-LDSGENGEVICH-IVGMVPFKLLSSSG 3036
Query: 628 ---VITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSP 683
I L R Y+ A + + LS + + D+ND V K ++
Sbjct: 3037 NFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTY 3096
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQK 742
+ + G + ++ + S + N + FL Q T I + G I T
Sbjct: 3097 EMVPF-SSEQGTLVTKVVAVDADSGH-NAWLSYHFL---QDSETSHFIIDQYTGEIRTST 3151
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE + + + + A + G + I + D NDN P F Y+ I EN +
Sbjct: 3152 SLDRETQSNHELILTASDGGNPVQ-TGTTLIKITVTDFNDNLPEFTQEVYKVNIHENIPL 3210
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVKFIGDSLDREKKI 859
+ I + A+D DEG NA Y+ +F + G +K G +LD+EK
Sbjct: 3211 NSTIFH---VNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGAIKTKG-TLDKEKNS 3266
Query: 860 MYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
Y +++ A D G LS + + + + D NDN P F E++ + E N G +
Sbjct: 3267 HYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVF---EKSQYIAYVPE---NNQPGAS 3320
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY-EFNSEVYI 976
I ++ +K D ++ G L +II N ++ S I Y N +
Sbjct: 3321 IFSIQAIDK---DTEENGKLLY---------SIITRNTEEMPS-----ISYISINPVTGV 3363
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVAR---SLPPESEFRLNISALDGGNLNDNISV-- 1031
++ S D E R F I I+A+ S P S + I+ D NDN V
Sbjct: 3364 IYAQRSFD-YEQDREFKIQ------IMAKDNGSPPLNSSAIVRITVTD---FNDNFPVFT 3413
Query: 1032 -RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V+ +++++ P+ T + N + + ++ + + N ++I P + +
Sbjct: 3414 QEVYKVNIHENIPI-NSTVLHVNASDKD--EGINAQITYSFSTTSANVLRMFYINPQNGE 3470
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ + G LDRE Y +T+ A D G D+NDNSP
Sbjct: 3471 I-----------KIKGTLDRERSSHYNITIQATDKG-SPPLSSWKTIALEVLDINDNSPV 3518
Query: 1151 F 1151
F
Sbjct: 3519 F 3519
Score = 111 bits (266), Expect = 2e-22
Identities = 127/469 (27%), Positives = 199/469 (42%), Gaps = 35/469 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +T+ D NDN P+F +Y S+ N + + + V A D D G N + Y TS
Sbjct: 2535 IRITVTDMNDNFPIF-GQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSK 2593
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
S F IN TG + E+ L+ E S Q A S A + I++T T
Sbjct: 2594 QASRS-FSINSETGEIKTKEN--LDFEKTKNYEISVQ-AKDGGGLVSHAKINIQITV-TD 2648
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP---FA 621
N + P F Y+ + N+ I ++V Q+ +D E + G FA
Sbjct: 2649 FND-NFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFA 2707
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVAL---QENANLSIVTNATVHVVDVNDERGVLLK 678
+ +SG IT ++ YD A + + LS + + ++D+ND K
Sbjct: 2708 INPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEK 2767
Query: 679 GAHSPIIFHVKENSAGA------AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + + + N GA AI + N +Y T N AN I
Sbjct: 2768 SNY--VAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNT--TSANNVHRIFSIN- 2822
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+G I T+ +D E+ Y ++V A+ ++S + + + + D NDNPP FE + Y
Sbjct: 2823 PNNGEITTKGNVDFEEVKYYDISVEAQDGGSLVSHSKV--LIQNVSDINDNPPKFEKSNY 2880
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD--ENTGVVKFIG 850
++ EN++ G+ I IKA D D N +Y++ E V V F+
Sbjct: 2881 VAYVTENNQPGSSIFS---IKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVT 2937
Query: 851 D--SLDREKKIMYKLSLVARDTGG-LSSEAELI-IMIGDENDNKPEFNQ 895
+ SLDRE + ++L L A D G + + LI I + D NDN P F Q
Sbjct: 2938 NQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQ 2986
Score = 109 bits (263), Expect = 4e-22
Identities = 124/517 (23%), Positives = 221/517 (42%), Gaps = 35/517 (6%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
+ET APL++ T + V T + Q + + +++ + D NDN P+F +Y
Sbjct: 2075 IETGAPLDRETESIHELVLTAFDGGN--PVQTGTAI-IKIIVSDFNDNAPIFT-QEVYTV 2130
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES-- 525
S+ N V + I +V A D D G N + Y +S + + F I+ +G V E+
Sbjct: 2131 SLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNT-FIIDSISGEVKTKENLD 2189
Query: 526 -PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGS 584
+E + + A D + +L + ++ ++P F Y+ +
Sbjct: 2190 FEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFN-------DNLPVFSQEVYKVSINE 2242
Query: 585 NVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV-PFAVEERSGVITVVDDLSRYNRP 641
N+ I +++ + ND E + + Y ++ + F + SG I ++L
Sbjct: 2243 NIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMTKENLDFEKTK 2302
Query: 642 MYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF 701
+Y+ A + + + V D ND + S I+ V N +
Sbjct: 2303 LYEISVQANDQYTGETGTALIRITVTDANDNFPMF-----SQEIYKVSINENMPLNSTVL 2357
Query: 702 HTNMSSIYGNGTGNVRFLIAN-QQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ + S + + ++ + T+ AI + G I T LDRE + Y +T+ A
Sbjct: 2358 YVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSGEIVTSSTLDREMKSHYDITIQAT 2417
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
+KG + + + + D NDN PVFE +TY +I EN++ G I I+A+D D
Sbjct: 2418 -DKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYS---IQASDKDS 2473
Query: 820 GTNALFMY-TLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG-LSSEA 877
NA +Y ++ +E +D + + + L+RE + ++++ L A D G + +
Sbjct: 2474 EENAKLVYSSITSNREENLRIDSDISEL-VLEIPLNRETESIHEIVLTAFDGGSPMQTGT 2532
Query: 878 ELI-IMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
LI I + D NDN P F Q E V I+ LN T
Sbjct: 2533 ALIRITVTDMNDNFPIFGQ--EVYTVSINENIPLNST 2567
Score = 108 bits (259), Expect = 1e-21
Identities = 107/415 (25%), Positives = 181/415 (43%), Gaps = 35/415 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIP+ +T++ ++A D D G+N QI Y F SA + + R F IN G
Sbjct: 2558 INENIPLNSTVLCVSANDKDQGINSQITYSF-----------SATSKQASRSFSINSETG 2606
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ +L E + +++ A DGG L + I++++ V D ND+FPVF + Y N+
Sbjct: 2607 EIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQEVYKVNIH 2666
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL--PFEISPLTGVLSVNGELDRETE 1113
E + +V+A+D D G NA +TY + T++ F I+P +G ++ G +D E
Sbjct: 2667 ENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEET 2726
Query: 1114 DKYILTVVARDNGXXX-XXXXXXXXXXXXXDVNDNSPKFYAFD---ELLEWKHPEAD--E 1167
Y ++V A+D D+NDN PKF + + E P A
Sbjct: 2727 KYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGASIYS 2786
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA---NDTDFIGNGN-GLILYSLPQRKN 1223
+ + ++ V + N V ++F+ N+ + GN
Sbjct: 2787 IQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDISV 2846
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ G +S + +L+ V+D+ D + P F Y + EN + S+ +
Sbjct: 2847 EAQDGGSLVSHSKVLIQNVSDIND-----NPPKFEKSNYVAYVTENNQPGSSIFSIKAID 2901
Query: 1284 H--YENFKMRYYILNENDTDIRRTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
EN K+ Y I N +++ I+P G + S DRE + +E+I+ A
Sbjct: 2902 KDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTA 2956
Score = 108 bits (259), Expect = 1e-21
Identities = 115/422 (27%), Positives = 185/422 (43%), Gaps = 48/422 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIP+ +TI +NA D D G+N QI Y F+S + V R F I+ ++G
Sbjct: 3204 IHENIPLNSTIFHVNASDKDEGINAQITYSFSST-----------SNNVLRIFSIHPKNG 3252
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ +L E S + + I A D G+ L+ ++R+ V D+ND+ PVF+K+ Y V
Sbjct: 3253 AIKTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVP 3312
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP----FEISPLTGVLSVNGELDR 1110
E + + A D D +N L Y I +T+ +P I+P+TGV+ D
Sbjct: 3313 ENNQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDY 3372
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E + ++ + ++A+DNG D NDN P F E+ + E +++
Sbjct: 3373 EQDREFKIQIMAKDNGSPPLNSSAIVRITVT-DFNDNFPVFT--QEVYKVNIHENIPINS 3429
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGLILYSLP---QRKNQQ 1225
+V+ + NA I + + AN +I NG I +R +
Sbjct: 3430 ----TVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHY 3485
Query: 1226 NL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
N+ G P LSS + + V D+ D + PVF Y + EN + S
Sbjct: 3486 NITIQATDKGSPPLSSWKTIALEVLDIND-----NSPVFEKSTYIAYVPENNQPGASIYS 3540
Query: 1279 LNLTEH--YENFKMRYYILNENDTDIRRT--FVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+ + EN K+ Y I+ N ++ T I+P G +Y RS D E +E+ +
Sbjct: 3541 IQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQII 3600
Query: 1335 AE 1336
A+
Sbjct: 3601 AK 3602
Score = 104 bits (250), Expect = 2e-20
Identities = 168/713 (23%), Positives = 307/713 (43%), Gaps = 98/713 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+D G+ A + Y K FS+D +G L+++K LD + + L +
Sbjct: 855 VNATDKDEGINAQIVYSF--SVSEKYFSIDLQSGMLYVKKPLDRETQ-----TIHELILT 907
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS NP+++ A + I + D NDNLP F + Y +SI EN+P +VL V ATD+D+G
Sbjct: 908 ASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGT 967
Query: 338 NGEFTYQLDDPKG------AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSV 390
N + Y G FSI+ SG ++ + + EA + VYAK+ +PS+
Sbjct: 968 NAQIMYSFSKTSGNNLHTSMFSINYTSG--EIKTKQNFNFEAKKFYEISVYAKDYGSPSL 1025
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
+ + RI + N + K Y + V + E + EQ + +V +
Sbjct: 1026 SCNASLTIRIT-------DQNDNVPKILYPSSESVDSSFEMVPVASEQ--GALITKVVAV 1076
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
DA+ + ++ ++ + S S + G+++ L + + Y N+TI +
Sbjct: 1077 DADSGHNAWLSYHVVQGSEPSLFSISQNTGEIR-TSRSLDREKVPWY------NITIQAT 1129
Query: 511 FKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
+ +P+ + + + I + +F ++S ++ I+ + G+
Sbjct: 1130 DRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNA 1189
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEEGVPFAVEER 625
+ + E S I + G+IR + E + +L + G P +
Sbjct: 1190 KLSYHVVQGSE---PSLFSISQNTGEIRTSQKPLDRETQSIHELILTASDGGNP--LRTG 1244
Query: 626 SGVITVVDDLSRYNRPMYDFEA--VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
+ +I ++ S N P++ E V++ ENA + N++V ++ D+ +G ++
Sbjct: 1245 TALIRIIVTDSNDNLPVFTQEVYKVSISENAPI----NSSVIILTATDKD----EGTNAQ 1296
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP 743
I + + + S +F N++ + G T V + + +T A DG P
Sbjct: 1297 ITYSISKTSENNFYTSVF--NINPVMGEITIKVSTSSSYYRIIT---TTASDG----GTP 1347
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
+ R + R+ V + + +Y+V+I ++N P+ NS
Sbjct: 1348 V-RTGTALIRVIVTDANDNTPVFTQEVYKVSI-----SENTPI------------NS--- 1386
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD-SLDREKKIMYK 862
T ++++ A+D DEGTNA Y+ F N+ K + + LDRE K +++
Sbjct: 1387 TVLRVN----ASDMDEGTNAQITYS-FSR------TSVNSLHAKLVLERPLDREIKNIHE 1435
Query: 863 LSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
L L A D G + A + +++ D NDN P F Q E KV I T +N T
Sbjct: 1436 LLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ--EVYKVSISENTPINST 1486
Score = 101 bits (242), Expect = 2e-19
Identities = 87/330 (26%), Positives = 147/330 (44%), Gaps = 34/330 (10%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ V + D NDN P+F Y V++ E TP + + +T T
Sbjct: 1355 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVN 1414
Query: 143 DIRA-FDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD------ 194
+ A ++P + ++H +++ +D G + + L +V+ DA D
Sbjct: 1415 SLHAKLVLERPLDREIKNIHELLLTASDGG-----TPVRTGTALIRVIVTDANDNTPVFT 1469
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL----FSLDSVN 250
+E V ++ I+ +L ++A D D G A + Y ++ L FS++ +
Sbjct: 1470 QEVYKVSISENTPINSTVL---RVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTS 1526
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + ++ LD + + N L + AS P++T A + + + D NDN P F +
Sbjct: 1527 GEIKTKRPLDRETK-----NIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEV 1581
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK------GAFSIDPRSGWLTVR 364
Y +SI EN P +VL+V A+D D+G N + TY FSI+P SG +T +
Sbjct: 1582 YKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTK 1641
Query: 365 NQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
LDREA +S + + A + NP GT
Sbjct: 1642 KP--LDREAQTSHELILTASDGGNPVRTGT 1669
Score = 95.5 bits (227), Expect = 1e-17
Identities = 116/495 (23%), Positives = 209/495 (42%), Gaps = 36/495 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + + D NDN PVF S Y + N + G I ++A D D +N ++Y
Sbjct: 2424 LSSRKTIRLDVSDINDNAPVFEKST-YIVYISENNEPGASIYSIQASDKDSEENAKLVYS 2482
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
TSN + + + + + E H + + A D S + A++ I
Sbjct: 2483 -SITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFD---GGSPMQTGTALIRIT 2538
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
VT + P F Y + N+ + ++V + ND + + ++Y ++
Sbjct: 2539 VT----DMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQ 2594
Query: 617 GV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERG 674
F++ +G I ++L Y+ A +S N + V D ND
Sbjct: 2595 ASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFP 2654
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ-DVTDDIAI- 732
V + + ++ EN + N S + + +V AI
Sbjct: 2655 VFTQEVYK---VNIHENIP--IHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAIN 2709
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEF-NKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G I T+ +D E+ Y ++V A+ +KG + + + + + I D NDNPP FE +
Sbjct: 2710 PKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSN 2769
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-------KEMFDVDENTG 844
Y ++ EN++ G I I+A D D N +Y++F +F ++ N G
Sbjct: 2770 YVAYVTENNQPGASIYS---IQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNG 2826
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM-IGDENDNKPEFNQIEENSKVR 903
+ G ++D E+ Y +S+ A+D G L S ++++I + D NDN P+F E+++ V
Sbjct: 2827 EITTKG-NVDFEEVKYYDISVEAQDGGSLVSHSKVLIQNVSDINDNPPKF---EKSNYVA 2882
Query: 904 IHRETKLNGTAGFTI 918
E G++ F+I
Sbjct: 2883 YVTENNQPGSSIFSI 2897
Score = 95.1 bits (226), Expect = 1e-17
Identities = 114/482 (23%), Positives = 207/482 (42%), Gaps = 65/482 (13%)
Query: 881 IMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLI 940
I+I D NDN P F + E KVRI T+ + ++ F ++ + + + D + L +
Sbjct: 21 IIISDANDNIPVFTK--EVYKVRI---TESSSSSLFEMVPLASEQGTLITKDTI-TLEIS 74
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP-PSKLSADALEVKRYFVINERHG 999
+P GT ++ A D D G+N RY + ++ K+ D ++
Sbjct: 75 ESTLP-GTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPE--------- 124
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+++ + L E++ +++ + D ND+ P F K Y + E
Sbjct: 125 -LVLEKYLDRETQ----------------TLIKIIISDANDNIPEFSKEVYKVKMSENTP 167
Query: 1060 TRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEISPLTGVLSVNGELDRETEDK 1115
+ VDATD D G NA +TY F + SD L F+I+P +G ++ +LD E+
Sbjct: 168 VNTTVLSVDATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQS 227
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y + + A D G D NDN+P+ L PE D +
Sbjct: 228 YEIAIEAMDGG---GFVAQTKVLIEIIDENDNAPEISIAS--LSAPIPE-DSMPG---TV 278
Query: 1176 VMMIPVYKATIEENAPI-----GTTVAKVFANDTDF--IGNGNGLILYSLPQRK---NQQ 1225
+ +I V+ N + G ++ ++ + + I + L +P
Sbjct: 279 IALIKVHDQDTGRNGEVDCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILAT 338
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+ G P LSST + + + DV D + P+F Y++ I E++ ++ +N T+
Sbjct: 339 DKGSPELSSTKSIKIAITDVNDHI-----PMFTQEVYKVSISESIPINTTVLQVNATDKD 393
Query: 1286 E--NFKMRYYIL-NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
E N ++ Y ++ D+ TF I+P +G + R+ + EV+ YE+ V A+ + Y +
Sbjct: 394 EGVNAQITYSLIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKSYIK 453
Query: 1343 EL 1344
++
Sbjct: 454 KV 455
Score = 95.1 bits (226), Expect = 1e-17
Identities = 97/423 (22%), Positives = 170/423 (40%), Gaps = 41/423 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ + + D NDN+P F Y V + E P F + + +T T
Sbjct: 3181 IKITVTDFNDNLPEFTQEVYKVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNN 3240
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK--PVLLLRKVLDYDAGDKEFQLV 200
+R F N N + ++++ K P L +K + D D
Sbjct: 3241 VLRIFSIHPKNGAIKTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSP 3300
Query: 201 IMASGKRIHKEILFPEP------IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSV 249
+ + I +P I AID+D L Y +I+ N ++ S++ V
Sbjct: 3301 VFEKSQYIAYVPENNQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPV 3360
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G ++ ++ D + Q F +Q+ A +P + A V I + D NDN P F +
Sbjct: 3361 TGVIYAQRSFDYE-----QDREFKIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQE 3415
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG----AFSIDPRSGWLTVRN 365
Y ++I EN+P +VL V A+DKD+G N + TY F I+P++G + ++
Sbjct: 3416 VYKVNIHENIPINSTVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKG 3475
Query: 366 QTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKTTYVFPDK 424
+R +H ++ ++ K + P S + + N+P+ EK+TY
Sbjct: 3476 TLDRERSSHYNITIQATDKGSPP------LSSWKTIALEVLDINDNSPVFEKSTY----- 3524
Query: 425 VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKSNAKVGTVIGK 481
+ EN ++ S +++ D +N +F + SN E S S + V G
Sbjct: 3525 IAYVPEN----NQPGASIYSIQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGV 3580
Query: 482 VKA 484
+ A
Sbjct: 3581 IYA 3583
Score = 94.3 bits (224), Expect = 2e-17
Identities = 76/318 (23%), Positives = 136/318 (42%), Gaps = 26/318 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGLTI 140
+ + + DVNDN P+F Y V E + G + + G + + + G+
Sbjct: 2970 IKITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIV-GMVP 3028
Query: 141 FKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK--PVLLLRKVLDYDAGDKEFQ 198
FK + + S + N + ++++ K P L +K + D D
Sbjct: 3029 FKLLSSSGNFYKIVTTSTLDRE---KNSHYNITIQATDKGSPPLSFQKTIRLDISDINDN 3085
Query: 199 LVIMASGKRIHKEILFPEP-------IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
+ ++ + F + A+D D G A L Y + ++ F +D G
Sbjct: 3086 APVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSHFIIDQYTG 3145
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ LD + + N + L + AS NP++T ++I + D NDNLPEF + Y
Sbjct: 3146 EIRTSTSLDRETQSNHE-----LILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVY 3200
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG----AFSIDPRSGWLTVRNQT 367
++I EN+P ++ V A+DKD+G N + TY FSI P++G ++ +
Sbjct: 3201 KVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNG--AIKTKG 3258
Query: 368 VLDREAHSSLRMKVYAKE 385
LD+E +S + + A +
Sbjct: 3259 TLDKEKNSHYNITIQATD 3276
Score = 93.9 bits (223), Expect = 3e-17
Identities = 105/415 (25%), Positives = 172/415 (41%), Gaps = 46/415 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN PI +++I L A D D G N QI Y SK S + F IN G
Sbjct: 1271 ISENAPINSSVIILTATDKDEGTNAQITYSI--------SKTSENNFYTS-VFNINPVMG 1321
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + S + +A DGG +RV V D ND+ PVF + Y ++ E
Sbjct: 1322 EITIKVSTSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISEN 1381
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ +V+A+D D G NA +TY + ++ L L + LDRE ++ +
Sbjct: 1382 TPINSTVLRVNASDMDEGTNAQITYSFSRT------SVNSLHAKLVLERPLDREIKNIHE 1435
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L + A D G D NDN+P F E+ + E +++ +V+
Sbjct: 1436 LLLTASDGG-TPVRTGTALIRVIVTDANDNTPVF--TQEVYKVSISENTPINS----TVL 1488
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTD----FIGNGNGLILYSLPQRKNQQNL------ 1227
+ NA I + ++ N I +G I P + +N+
Sbjct: 1489 RVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRETKNIHELLLT 1548
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNL 1281
G P + TA++ V V D D + PVF Y++ I EN +N+ V V+ +
Sbjct: 1549 ASDGGTPVRTGTALIRVIVTDAND-----NTPVFTQEVYKVSISENTPINSTVLRVNASD 1603
Query: 1282 TEHYENFKMRYYILNENDTDIRRT-FVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N ++ Y + + + F I+P +G + + DRE + ++E+I+ A
Sbjct: 1604 MDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTA 1658
Score = 92.7 bits (220), Expect = 7e-17
Identities = 121/504 (24%), Positives = 206/504 (40%), Gaps = 45/504 (8%)
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF-------LIPENIPIGTT 949
E++ + +H + K NG + K DV+ P+F +PEN G +
Sbjct: 1871 EQHKEFAMHVQAKDNGYPSHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGAS 1930
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
I ++A D+DSG N ++ Y ++ +S+ R++ ++ +L
Sbjct: 1931 IYTVHATDVDSGDNAKLIYSISNANTEDFPLISSTG----RFY-------RIVTTNNLDR 1979
Query: 1010 ESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E + + I A D G + V + DVND+ P+F K Y+ + E ++
Sbjct: 1980 ERTPFYNITILATDRGYPQRTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENNLPGALIY 2039
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARD 1124
+ A D D G NA +TY I ++TD F +S + + LDRETE + L + A D
Sbjct: 2040 SLHAKDLDVGDNAKVTYSILNTNTD--FSVSSYFSINIETGAPLDRETESIHELVLTAFD 2097
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLEWKHPEADEL----SNHNFE-SVM 1177
G D NDN+P F + L P + +N E S
Sbjct: 2098 GGNPVQTGTAIIKIIVS-DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNS 2156
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN-GLILYSLPQRKNQQNLGLPSLSSTA 1236
I Y A + A + T + + + N + I + ++ G PSL+S+
Sbjct: 2157 QITYYFAASSKQA-MNTFIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSST 2215
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYI 1294
L + + D D + PVF Y++ I EN+ N+ + VS N + N ++RYY
Sbjct: 2216 NLRICIVDFNDNL-----PVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYF 2270
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAED 1354
+ + I TF+I+ +G + + D E YE+ V+A Q +I D
Sbjct: 2271 -STSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQANDQYTGETGTALIRITVTD 2329
Query: 1355 VLEGMTKYDVKVVVRIKDVNDNSP 1378
+ + ++ +N+N P
Sbjct: 2330 ANDNFPMFSQEIYK--VSINENMP 2351
Score = 92.3 bits (219), Expect = 9e-17
Identities = 88/357 (24%), Positives = 152/357 (42%), Gaps = 34/357 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTV-------- 134
+ + + D NDN PIF Y V+++E P +T
Sbjct: 2109 IKIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQ 2168
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSI---VSGNDDGHFALESSHKPVLLLRKVLD-Y 190
I I + K N + + D G +L SS + + D
Sbjct: 2169 AMNTFIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNL 2228
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL--FSLDS 248
+E V + I+ IL+ + A D+D G+ + +RY + + + L F ++S
Sbjct: 2229 PVFSQEVYKVSINENIPINSTILY---VSANDKDEGINSQIRYYFSTSSKQILNTFIINS 2285
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
++G++ ++ LD + + + + VQA+ +T A + I + D NDN P F
Sbjct: 2286 ISGAIMTKENLDFE-----KTKLYEISVQANDQYTG-ETGTALIRITVTDANDNFPMFSQ 2339
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK----GAFSIDPRSGWLTVR 364
+ Y +SI EN+P +VL V A+DKD+G N + TY AF+I+P+SG +
Sbjct: 2340 EIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSG--EIV 2397
Query: 365 NQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL-EKTTYV 420
+ LDRE S + + A + + S++ + + NAP+ EK+TY+
Sbjct: 2398 TSSTLDREMKSHYDITIQATDKGSPPL----SSRKTIRLDVSDINDNAPVFEKSTYI 2450
Score = 89.0 bits (211), Expect = 9e-16
Identities = 101/413 (24%), Positives = 176/413 (42%), Gaps = 36/413 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G +I + A+D D+ NG++ VY + + A V R F IN +G
Sbjct: 2774 VTENNQPGASIYSIQAIDEDTEENGKV-------VYSIFTNNTTSANNVHRIFSINPNNG 2826
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVF-VKDVNDHFPVFKKTWYNFNVEE 1056
+ ++ E + +++ A DGG+L + V + V D+ND+ P F+K+ Y V E
Sbjct: 2827 EITTKGNVDFEEVKYYDISVEAQDGGSLVSHSKVLIQNVSDINDNPPKFEKSNYVAYVTE 2886
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP----FEISPLTGVLSVNGELDRET 1112
+ + A D D +N + Y I + + I+P+TG ++ LDRET
Sbjct: 2887 NNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRET 2946
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ + L + A D G DVNDN P F E+ +K P +++ +
Sbjct: 2947 QSNHELILTASDGG-NPVQTGTTLIKITVTDVNDNFPVF--TQEV--YKTPVSEDSTLGT 3001
Query: 1173 FESVMMIPVYKATIEENAP-IGTTVAKVFANDTDFIGNGNGLILYS-LPQRKNQQ----- 1225
V +I + EN I V V GN ++ S L + KN
Sbjct: 3002 V--VALIEGHDLDSGENGEVICHIVGMVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITI 3059
Query: 1226 ---NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
+ G P LS + + ++D+ D + +K + E+ ++V+++
Sbjct: 3060 QATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQG-TLVTKVVAVD-A 3117
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N + Y+ L +++T F+ID G + S DRE + +E+I+ A
Sbjct: 3118 DSGHNAWLSYHFLQDSETS---HFIIDQYTGEIRTSTSLDRETQSNHELILTA 3167
Score = 87.4 bits (207), Expect = 3e-15
Identities = 117/492 (23%), Positives = 204/492 (41%), Gaps = 35/492 (7%)
Query: 434 YYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
Y Q + +++ + D NDN PVF S LY + N G I V A D D G N
Sbjct: 1887 YPSHQSHKWKFIKLDISDVNDNPPVFRKS-LYTTYLPENNLPGASIYTVHATDVDSGDNA 1945
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGT-VSVAESPILEGRHALFVEASDQPANPS-ERRYS 551
++Y + + T F + +TG + + L+ F + + +R S
Sbjct: 1946 KLIYSISNAN----TEDFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQRTS 2001
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYD 609
++ +E++ + P F+ Y+ ++ N G + + D + V+Y
Sbjct: 2002 KKMIGVEIS----DVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYS 2057
Query: 610 LLHGYEEGVPFAVEERSGV-ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV- 667
+L+ F+V + I L R +++ A + N A + ++
Sbjct: 2058 ILN---TNTDFSVSSYFSINIETGAPLDRETESIHELVLTAF-DGGNPVQTGTAIIKIIV 2113
Query: 668 -DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND + + ++ + EN + N N F +++Q +
Sbjct: 2114 SDFNDNAPIFTQEVYT---VSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAM 2170
Query: 727 TDDIAIAEDGTIFTQKPLDREKRD-VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I + G + T++ LD EK + +++ ++A+ + G S + I I D NDN P
Sbjct: 2171 NTFIIDSISGEVKTKENLDFEKIEREFQIQIMAK-DHGSPSLNSSTNLRICIVDFNDNLP 2229
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM---FDVDEN 842
VF Y+ I EN I + I + A D DEG N+ Y K++ F ++
Sbjct: 2230 VFSQEVYKVSINENIPINSTIL---YVSANDKDEGINSQIRYYFSTSSKQILNTFIINSI 2286
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDT-GGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
+G + ++LD EK +Y++S+ A D G + A + I + D NDN P F+Q E K
Sbjct: 2287 SGAI-MTKENLDFEKTKLYEISVQANDQYTGETGTALIRITVTDANDNFPMFSQ--EIYK 2343
Query: 902 VRIHRETKLNGT 913
V I+ LN T
Sbjct: 2344 VSINENMPLNST 2355
Score = 86.6 bits (205), Expect = 5e-15
Identities = 109/416 (26%), Positives = 180/416 (43%), Gaps = 53/416 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++P G I K+ A+D DSG N + Y + S+ S F I++
Sbjct: 1059 MVPVASEQGALITKVVAVDADSGHNAWLSYHV-----VQGSEPSL--------FSISQNT 1105
Query: 999 GHVIVARSLPPESE--FRLNISALDGGNLN-DNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
G + +RSL E + + I A D G+ + NI +++ + DVND+ PVF K+ Y +
Sbjct: 1106 GEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYI 1165
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE-LDRETE 1113
E + ++ A+D D G NA L+Y + F IS TG + + + LDRET+
Sbjct: 1166 AENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQ 1225
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+ L + A D G D NDN P F E+ + E +++
Sbjct: 1226 SIHELILTASDGG-NPLRTGTALIRIIVTDSNDNLPVF--TQEVYKVSISENAPINS--- 1279
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFAND-TDFIGNGN---GLILYSLPQRKNQQNL-- 1227
SV+++ NA I +++K N+ + N N G I + + +
Sbjct: 1280 -SVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKVSTSSSYYRIIT 1338
Query: 1228 ------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSL 1279
G P + TA++ V V D D + PVF Y++ I EN +N+ V V+
Sbjct: 1339 TTASDGGTPVRTGTALIRVIVTDAND-----NTPVFTQEVYKVSISENTPINSTVLRVNA 1393
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + N ++ Y RT V + + L L R DRE+K+ +E+++ A
Sbjct: 1394 SDMDEGTNAQITY--------SFSRTSV-NSLHAKLVLERPLDREIKNIHELLLTA 1440
Score = 85.8 bits (203), Expect = 8e-15
Identities = 72/307 (23%), Positives = 135/307 (43%), Gaps = 23/307 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S+ ++ + + D+NDN P+F + Y V + E G + + L
Sbjct: 2420 GSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKL 2479
Query: 133 TVP-------RGLTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
L I DI + P N +H +++ D G + + +
Sbjct: 2480 VYSSITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITV 2539
Query: 185 RKVLD-YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR-- 241
+ D + +E V + ++ +L + A D+D G+ + + Y + + +
Sbjct: 2540 TDMNDNFPIFGQEVYTVSINENIPLNSTVLC---VSANDKDQGINSQITYSFSATSKQAS 2596
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
+ FS++S G + ++ LD + N + + VQA + A+ ++I + D ND
Sbjct: 2597 RSFSINSETGEIKTKENLDFEKTKNYE-----ISVQAKDGGGLVSHAKINIQITVTDFND 2651
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPR 357
N P F + Y ++I EN+P +VLQV A+DKD+G N + TY + F+I+P+
Sbjct: 2652 NFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPK 2711
Query: 358 SGWLTVR 364
SG +T +
Sbjct: 2712 SGEITTK 2718
Score = 85.4 bits (202), Expect = 1e-14
Identities = 82/317 (25%), Positives = 131/317 (41%), Gaps = 23/317 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ + + D NDN P+F Y V+++E P + + LT +
Sbjct: 2323 IRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQ 2382
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHF--ALESSHK--PVLLLRKVLDYDAGDKEFQ 198
AF + + V S + H+ ++++ K P L RK + D D
Sbjct: 2383 ATNAFAINPQS--GEIVTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDVSDINDN 2440
Query: 199 LVIMASGKRIHKEILFPEP------IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
+ I EP I A D+D A L Y I+ N + +DS
Sbjct: 2441 APVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYSSITSNREENLRIDSDISE 2500
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L LE L+ + E + + + A +P++T A + I + D+NDN P F + Y
Sbjct: 2501 LVLEIPLNRETE-----SIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYT 2555
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTV 368
+SI EN+P +VL V A DKDQG N + TY +FSI+ +G ++ +
Sbjct: 2556 VSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETG--EIKTKEN 2613
Query: 369 LDREAHSSLRMKVYAKE 385
LD E + + V AK+
Sbjct: 2614 LDFEKTKNYEISVQAKD 2630
Score = 83.4 bits (197), Expect = 4e-14
Identities = 111/468 (23%), Positives = 181/468 (38%), Gaps = 64/468 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN G +I + A D DS N ++ Y + ++ +D E+ +N
Sbjct: 2453 ISENNEPGASIYSIQASDKDSEENAKLVYSSITSNREENLRIDSDISELVLEIPLNRE-- 2510
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
ES + ++A DGG+ +R+ V D+ND+FP+F + Y ++ E
Sbjct: 2511 ---------TESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSINEN 2561
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ V A D D G N+ +TY + F I+ TG + LD E
Sbjct: 2562 IPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKTKN 2621
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y ++V A+D G D NDN P F E+ +K + + H+ +
Sbjct: 2622 YEISVQAKDGG-GLVSHAKINIQITVTDFNDNFPVF--TQEV--YKVNIHENIPIHS--T 2674
Query: 1176 VMMIPVYKATIEENAPI----GTT---VAKVFA---NDTDFIGNGN----GLILYSLPQR 1221
V+ + NA I GTT V ++FA + GN Y + +
Sbjct: 2675 VLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQ 2734
Query: 1222 KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL 1281
+ G P+LSS + + + D+ D + P F Y + EN + S+
Sbjct: 2735 AQDGDKGSPTLSSLKTIRLDILDIND-----NPPKFEKSNYVAYVTENNQPGASIYSIQA 2789
Query: 1282 TEH--YENFKMRYYILNENDT---DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ EN K+ Y I N T ++ R F I+P NG + + D E Y++ V A+
Sbjct: 2790 IDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQ 2849
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
+ + ++ + D+NDN PKF N
Sbjct: 2850 DG------------------GSLVSHSKVLIQNVSDINDNPPKFEKSN 2879
Score = 81.0 bits (191), Expect = 2e-13
Identities = 106/470 (22%), Positives = 191/470 (40%), Gaps = 58/470 (12%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGDDLVRI----GAGLNQISAYLSVTVYIEDVNDNVPIFLD 99
+DSD + V++ L + + ++V G+ + +A + +TV D+NDN PIF
Sbjct: 2494 IDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITV--TDMNDNFPIFGQ 2551
Query: 100 TPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFD--------RDK 151
Y V+++E P + +T T + R+F + K
Sbjct: 2552 EVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTK 2611
Query: 152 PNTP-NSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAG----DKEFQLVIMASG 205
N +Y I V D G SH + + V D++ +E V +
Sbjct: 2612 ENLDFEKTKNYEISVQAKDGGGLV---SHAKINIQITVTDFNDNFPVFTQEVYKVNIHEN 2668
Query: 206 KRIHKEILFPEPIHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDA 263
IH +L ++A D+D G+ A + Y + N ++F+++ +G + + +D +
Sbjct: 2669 IPIHSTVL---QVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEE 2725
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
+ +Q Q +P ++ + +++LD+NDN P+FE Y + EN G
Sbjct: 2726 TKYYDIS---VQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGA 2782
Query: 324 SVLQVMATDKDQGENGEFTYQL--------DDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
S+ + A D+D ENG+ Y + ++ FSI+P +G +T + +D E
Sbjct: 2783 SIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGN--VDFE--- 2837
Query: 376 SLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTTYVFPDKVGTKTENIEY 434
+K Y G+ ++ + N P EK+ Y V TEN
Sbjct: 2838 --EVKYYDISVEAQDGGSLVSHSKVLIQNVSDINDNPPKFEKSNY-----VAYVTEN--- 2887
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVF--VPSNLYEFSMKSNAKVGTVIGKV 482
++ S +++ D +N V + +N EFS S + V G V
Sbjct: 2888 -NQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFV 2936
Score = 79.4 bits (187), Expect = 7e-13
Identities = 98/412 (23%), Positives = 171/412 (41%), Gaps = 64/412 (15%)
Query: 8 LNLQPVDREEDAHL---FTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEG 64
+N +D +A + F+ +N H ++L + +D + +N+ + L +G
Sbjct: 1391 VNASDMDEGTNAQITYSFSRTSVNSLHAKLVLERPLDREI-----KNIHELLLTAS--DG 1443
Query: 65 DDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI 124
VR G L + V + D NDN P+F Y V++ E TP + +
Sbjct: 1444 GTPVRTGTAL--------IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDM 1495
Query: 125 GPSLTIPLTVPRGLTIFKDIRA-----------FDRDKP-NTPNSDVHYSIVSGNDDGHF 172
+T T + A +P + ++H +++ +D G
Sbjct: 1496 DEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRETKNIHELLLTASDGG-- 1553
Query: 173 ALESSHKPVLLLRKVLDYDAGD------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLG 226
+ + L +V+ DA D +E V ++ I+ +L ++A D D G
Sbjct: 1554 ---TPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVL---RVNASDMDEG 1607
Query: 227 VGATLRYEL----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
A + Y ++ +FS++ +G + +K LD +A+ + + L + AS
Sbjct: 1608 TNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHE-----LILTASDGG 1662
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NP++T A ++I + D NDNLP F Y +SI EN G VL V A+ N + T
Sbjct: 1663 NPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNAS-----SNAKIT 1717
Query: 343 YQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSV 390
Y + + FSI+ +G L Q D E H M++ AK+ PS+
Sbjct: 1718 YSISETNTMSPYFSINIETGVLYA--QQSFDYEQHKQFEMEIMAKDNGFPSM 1767
Score = 77.4 bits (182), Expect = 3e-12
Identities = 75/318 (23%), Positives = 132/318 (41%), Gaps = 23/318 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ + I D NDN+P F Y V + E TP L +T T
Sbjct: 139 IKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSFSKTSDN 198
Query: 143 DIRA--FDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
+ FD + + T D+ + V + A++ + D D
Sbjct: 199 QLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKVLIEIIDENDNAP 258
Query: 198 QLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
++ I + I ++ + P + A+ DQD G + +++ ++ S S +
Sbjct: 259 EISIASLSAPIPEDSM-PGTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVSSSSRYYRI 317
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
LD + + + + + A+ +P ++ ++I + D+ND++P F + Y +
Sbjct: 318 ITASFLDRE-----KVPWYNITILATDKGSPELSSTKSIKIAITDVNDHIPMFTQEVYKV 372
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG------AFSIDPRSGWLTVRNQT 367
SI E++P +VLQV ATDKD+G N + TY L G FSI+P SG ++ +
Sbjct: 373 SISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASG--EIKTKR 430
Query: 368 VLDREAHSSLRMKVYAKE 385
L+ E M V AK+
Sbjct: 431 NLNFEVQKHYEMSVEAKD 448
Score = 75.4 bits (177), Expect = 1e-11
Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 14/203 (6%)
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
D F++V +AS + L + + A+D D G A L Y ++ G++ LFS+ G +
Sbjct: 1054 DSSFEMVPVAS----EQGALITKVV-AVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEI 1108
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
+ LD + + + + +QA+ +P + +++++ D+NDN P F Y
Sbjct: 1109 RTSRSLDRE-----KVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVA 1163
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDR 371
I EN G S+ ++ A+D D G+N + +Y + FSI +G + +Q LDR
Sbjct: 1164 YIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPSLFSISQNTGEIRT-SQKPLDR 1222
Query: 372 EAHSSLRMKVYAKE-TNPSVVGT 393
E S + + A + NP GT
Sbjct: 1223 ETQSIHELILTASDGGNPLRTGT 1245
Score = 68.1 bits (159), Expect = 2e-09
Identities = 74/316 (23%), Positives = 131/316 (41%), Gaps = 38/316 (12%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT---IPLTVPRGLTIF 141
+ I D NDN+P+F Y V + E + + + L + G +T I L +
Sbjct: 21 IIISDANDNIPVFTKEVYKVRITESSSSSLFEMVPLASEQGTLITKDTITLEISESTLPG 80
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGND----DGHFALESSHKPVLLLRKVLDY------- 190
+ + P+ + V I+S N + S P L+L K LD
Sbjct: 81 THLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPELVLEKYLDRETQTLIK 140
Query: 191 ----DAGD------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
DA D KE V M+ ++ +L + A D+D G+ A + Y +D
Sbjct: 141 IIISDANDNIPEFSKEVYKVKMSENTPVNTTVL---SVDATDKDEGLNAQITYSFSKTSD 197
Query: 241 RKL----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+L F ++ +G + +++LD ++ ++ + ++A ++ AQ +V IE+
Sbjct: 198 NQLHTGTFDINPTSGKITTKRDLDFES-----VQSYEIAIEA--MDGGGFVAQTKVLIEI 250
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
+D NDN PE + + I E+ G + + D+D G NGE Q+ +
Sbjct: 251 IDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVSS 310
Query: 357 RSGWLTVRNQTVLDRE 372
S + + + LDRE
Sbjct: 311 SSRYYRIITASFLDRE 326
Score = 66.9 bits (156), Expect = 4e-09
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 8/114 (7%)
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ Q ++I + D NDN+PEF + Y + + EN P +VL V ATDKD+G N + TY
Sbjct: 133 RETQTLIKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSF 192
Query: 346 DDPK------GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
G F I+P SG +T + LD E+ S + + A + V T
Sbjct: 193 SKTSDNQLHTGTFDINPTSGKITTKRD--LDFESVQSYEIAIEAMDGGGFVAQT 244
Score = 65.3 bits (152), Expect = 1e-08
Identities = 77/369 (20%), Positives = 149/369 (40%), Gaps = 43/369 (11%)
Query: 8 LNLQPVDREEDAHL---FTYRDLNRTHVSVILAQSIDSLVDSDSP---QNVVKFRLGCDF 61
+N +D +A + F+ +N H S+ + + P + L
Sbjct: 1599 VNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTA 1658
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI 121
+G + VR G L QI + D NDN+P+F + Y V++ E T G + +
Sbjct: 1659 SDGGNPVRTGTALIQI--------IVTDANDNLPVFTEVLYTVSISENTAVGS-VVLCVN 1709
Query: 122 APIGPSLTIPLTVPRGLTIFKDIRA-----FDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
A +T ++ ++ + I + + + + D+G ++ S
Sbjct: 1710 ASSNAKITYSISETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMTS 1769
Query: 177 SHKPVL-LLRKVLDYDAGD------KEFQLVIMASGKRIHKEILF----PEPIHAIDQDL 225
+ ++ ++ +V+ DA D +E V ++ ++ +L P+ + A D D
Sbjct: 1770 NTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLDT 1829
Query: 226 GVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
G + + Y + + N FS++ G L+ ++ D + Q F + VQA
Sbjct: 1830 GENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYE-----QHKEFAMHVQAKD 1884
Query: 281 LNNPLKTAQAR--VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P + +++++ D+NDN P F Y + EN G S+ V ATD D G+N
Sbjct: 1885 NGYPSHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDN 1944
Query: 339 GEFTYQLDD 347
+ Y + +
Sbjct: 1945 AKLIYSISN 1953
Score = 63.7 bits (148), Expect = 4e-08
Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 7/178 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQV 276
+HA D D G A L Y + + N F L S G + + +LD E N +L
Sbjct: 1934 VHATDVDSGDNAKLIYSISNANTED-FPLISSTGRFYRIVTTNNLDRERTPFYNITIL-- 1990
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P +T++ + +E+ D+NDN P F Y+ + EN G + + A D D G
Sbjct: 1991 -ATDRGYPQRTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVG 2049
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+N + TY + + FS+ + + LDRE S + + A + NP GT
Sbjct: 2050 DNAKVTYSILNTNTDFSVSSYFS-INIETGAPLDRETESIHELVLTAFDGGNPVQTGT 2106
Score = 63.3 bits (147), Expect = 5e-08
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 244 FSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F L S +G+ + + LD E N N + +QA+ +P + Q + +++ D+NDN
Sbjct: 3029 FKLLSSSGNFYKIVTTSTLDREKNSHYN---ITIQATDKGSPPLSFQKTIRLDISDINDN 3085
Query: 303 LPEFEVDFYNISIVE-NLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
P FE Y +V + G V +V+A D D G N +Y D F ID +G
Sbjct: 3086 APVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSHFIIDQYTG 3145
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+R T LDRE S+ + + A + NP GT
Sbjct: 3146 --EIRTSTSLDRETQSNHELILTASDGGNPVQTGT 3178
Score = 61.7 bits (143), Expect = 2e-07
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 12/208 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLD--SVNGSL-FLEKELDLDAEHNLQANTFVL 274
I AID+D + Y IS N + S+ S+N F+ + LD E Q+N ++
Sbjct: 2897 IKAIDKDTEENGKVVYS-ISNNTVEFSSVSYISINPVTGFVTNQTSLDRE--TQSNHELI 2953
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ AS NP++T ++I + D+NDN P F + Y + E+ G V + D D
Sbjct: 2954 -LTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLD 3012
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
GENGE + + + + + LDRE +S + + A + +
Sbjct: 3013 SGENGEVICHIVGMVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPL--- 3069
Query: 395 ADSQRIAKWRRQPLETNAPL-EKTTYVF 421
Q+ + + NAP+ EK+TY +
Sbjct: 3070 -SFQKTIRLDISDINDNAPVFEKSTYTY 3096
Score = 54.0 bits (124), Expect = 3e-05
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S+ + + +LD NDN+PVF S + ++N + G I ++A+D D +NG + Y
Sbjct: 3499 LSSWKTIALEVLDINDNSPVFEKSTYIAYVPENN-QPGASIYSIQAIDKDTEENGKLFYS 3557
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAES 525
+ T L+ TS INP TG + S
Sbjct: 3558 IITSNTEELSSTSYISINPVTGVIYAQRS 3586
Score = 52.4 bits (120), Expect = 9e-05
Identities = 73/335 (21%), Positives = 120/335 (35%), Gaps = 45/335 (13%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+ V + D NDN P+F Y V++ E TP + + +T T
Sbjct: 1563 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVN 1622
Query: 143 DIRA-----------FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+ A KP + + ++ DG + + L +++ D
Sbjct: 1623 SLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTG----TALIQIIVTD 1678
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK-LFSLDSVN 250
A D + I + + ++ A + Y + N FS++
Sbjct: 1679 ANDNLPVFTEVLYTVSISENTAVGSVVLCVNASSN--AKITYSISETNTMSPYFSINIET 1736
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD------LNDNLP 304
G L+ ++ D + Q F +++ A P T+ + I ++D NDN P
Sbjct: 1737 GVLYAQQSFDYE-----QHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAP 1791
Query: 305 EFEVDFYNISIVENLPNGFSVL-------QVMATDKDQGENGEFTYQLDDP-------KG 350
F + Y +SI EN P VL V A+D D GEN + Y + +
Sbjct: 1792 VFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLDTGENSKVIYSVFNTNTEAFPVSS 1851
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
FSI+ +G L Q D E H M V AK+
Sbjct: 1852 YFSINIETGVLYA--QRSFDYEQHKEFAMHVQAKD 1884
>UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 20 SCAF14744, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 2413
Score = 179 bits (435), Expect = 6e-43
Identities = 247/919 (26%), Positives = 372/919 (40%), Gaps = 106/919 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V VTL D NDN PVF P Y ++K N G+ + V A DPDLG+NG V Y
Sbjct: 646 LRSAGKVNVTLRDVNDNRPVFYPLQ-YFANVKENEPSGSYVTTVSATDPDLGRNGTVKYM 704
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ T F IN NTG +S E + + L V A+D R ++ A+VT
Sbjct: 705 ITAGDAAT----FHINGNTGKISTLVPLDREEKTTYQLQVTAAD---GSGLRSHTPAIVT 757
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ V T+ N P F Y F + NVG+GT VG + +VSY + G +
Sbjct: 758 VSVL-DTQDNPPV---FSQKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQR 813
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G+ FAV +G IT + R + + + VA + N TV D+ND
Sbjct: 814 GL-FAVNS-AGQITASSPIDREEQSFHQLKVVARAGQITGEVSVNITVK--DLNDNAPRF 869
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED- 735
+ H+ + HV + IF S G V + + +Q+ I E
Sbjct: 870 I---HA--VEHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSL--KQNPRGLFHIHEKH 922
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I PL+ Y + VIAE + GV + + + D NDN PVF+ +YE
Sbjct: 923 GLITLTGPLEVTASS-YEVEVIAE-DMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVL 980
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLD 854
I E+ + + ++ATD D G N +Y + G ++F + + + +I LD
Sbjct: 981 IPESEPVNSRFFK---VEATDKDSGFNGEIVYDIAGGNTGDVFGIFPDGQL--YIKAELD 1035
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
RE + Y L LVARD LS+ + +++ D NDN+P FN N E +
Sbjct: 1036 REIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFN--STNYVFHFEEEQQRGS 1093
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
G FA D D GP + + +LNA+ + Q F+
Sbjct: 1094 LVG---------RVFAEDKD-FGPNSEVRYTFEMPQPNFELNAITGELSSTAQ----FDR 1139
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVR 1032
E S + V + V++ G + R L +++ ++ I ++NDN
Sbjct: 1140 E-----SLMRQRGAAVFSFVVVSSDQG---LPRPLKDQAKVQVYIQ-----DINDN--QP 1184
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
F KDV Y +V E+ L +V A+D D +N + Y + + +
Sbjct: 1185 KFTKDV-----------YQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAEGNEEGQ 1233
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F I +G +++ G+LD ET Y L ++A D G D NDNSP F
Sbjct: 1234 FMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGG-AEPLSSSCMLSISVLDENDNSPSF- 1291
Query: 1153 AFDELLEWKHPEADELSNHNF-ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
D L N E V + NA I ++ + T I
Sbjct: 1292 ------PKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGTFSISPNT 1345
Query: 1212 GLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRY 1261
G I Q++ G PS SS+ +++ V D D + P+F
Sbjct: 1346 GSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFND-----NPPIFTPGD 1400
Query: 1262 YELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR 1319
I EN V V ++ + T+ N ++ Y I+ + F ID G LY +
Sbjct: 1401 IFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQQ--VPRGNHFSIDASTGVLYTNQ 1458
Query: 1320 SPDREVKDTYEVIVRAERQ 1338
DRE + +E+ V+A Q
Sbjct: 1459 EVDREFSNLFELTVKATDQ 1477
Score = 138 bits (334), Expect = 1e-30
Identities = 183/696 (26%), Positives = 281/696 (40%), Gaps = 87/696 (12%)
Query: 220 AIDQDLGVGAT--LRYELISGNDRKLFSLD-SVNGS-----LFLEKELDLDAEHNLQANT 271
A D D+G Y ++ GN+++ F LD +VN S L L LD E
Sbjct: 144 ATDTDIGSNGVDHTTYRIVKGNEQRKFRLDITVNPSGEGAFLHLVSTGGLDRE---VTPF 200
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ L ++ P +V + + D+NDN P FE D Y S++E+ G S+LQV A+
Sbjct: 201 YQLLIEVEDKGEPKTFGYLQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTAS 260
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSV 390
D D+ N E Y LD+ + F IDP++G + ++ LD E+ + ++A + PS+
Sbjct: 261 DGDEAANAEIRYFLDE-ETPFQIDPKTGTIIIKEG--LDYESRREYSLTIHAVDNGVPSL 317
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
G + A + + N P+ K Y FP T DE V V LL
Sbjct: 318 SG-----RAEATIKLLDVNDNDPVVKFRY-FP-----TTSKFASVDENAQ--VGTVVALL 364
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
+D++ S +N + I LG N +++ TSP
Sbjct: 365 TVSDSD-----------SSAANGNISVSI---------LGGNEQRHFEVH-------TSP 397
Query: 511 FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
PN + VA E + L V SD P R S A + I V + P
Sbjct: 398 V---PNLSLIKVASVLDRERISSYNLTVSVSDN-GKPVARS-SFASLVIFV--NDINDHP 450
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN-DVSYDLLHGYEEGVPFAVEERS 626
I F Y + ++ G+ + + D QN ++ Y L+ G G F++ E S
Sbjct: 451 PI--FQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNALGW-FSISENS 507
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLKGAHSPII 685
G++T L R A + I T +++ DVND+ +
Sbjct: 508 GLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQST----- 562
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFTQK 742
FHV A Q+ + + G +RF + D G + T
Sbjct: 563 FHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAV 622
Query: 743 PLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LDRE++ Y + V + + + AG +V + + D NDN PVF Y + EN
Sbjct: 623 ELDREEQASYLLHVQVTDGGSPPLRSAG--KVNVTLRDVNDNRPVFYPLQYFANVKENEP 680
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
G+ + + ATD D G N Y + F ++ NTG + + LDRE+K Y
Sbjct: 681 SGSYV---TTVSATDPDLGRNGTVKYMITAGDAATFHINGNTGKISTL-VPLDREEKTTY 736
Query: 862 KLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQ 895
+L + A D GL S I+ + D DN P F+Q
Sbjct: 737 QLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQ 772
Score = 137 bits (331), Expect = 3e-30
Identities = 223/888 (25%), Positives = 361/888 (40%), Gaps = 110/888 (12%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSL--TIP 131
S+ + V +++ D NDN PIF ++ E P + + A I L +I
Sbjct: 1377 SSSIPVIIHVRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIV 1436
Query: 132 LTVPRGLTIFKDIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK-V 187
VPRG D + + + S++ V D LE+ + + V
Sbjct: 1437 QQVPRGNHFSIDASTGVLYTNQEVDREFSNLFELTVKATDQA-VPLETRRFALKNVTIWV 1495
Query: 188 LDYDAGDKEF--QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
D + F Q ++A + IL + A D D G + YEL+ G D F
Sbjct: 1496 TDQNDNIPTFLSQNALVAEPNIMIGSIL--TTVVAYDPDEGANGEVEYELVEG-DSGTFI 1552
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+D +G + L +L L + L V A+ KT++ + I L L+ P
Sbjct: 1553 MDRYSGDIRLASQL---VPSQL---VYSLTVSATDHGTERKTSRTDLTIILQGLDG--PV 1604
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGA---FSIDPRS 358
F Y + E P G +V+ + A+ +G + Y + K A F+I S
Sbjct: 1605 FSQPKYITILKEGQPPGTNVISLDASSP-RGSTSKVEYFIVAVHSGGKAAGRLFTIGRHS 1663
Query: 359 GWLTVRNQTVLDREAHSSLRM-KVYAKETNPSV----------VGTFAD---------SQ 398
G ++ LDRE S L + VYA E++ S +G F D S
Sbjct: 1664 G--VIQTAAELDREQGSDLYLVDVYAIESDASQPRTQRAETQNLGGFLDRLDQENRAGSP 1721
Query: 399 RIAKWRRQPL---ETNAPLEKTTYVFPDKVGTKTENIEYYD-----EQLM-------SFV 443
A W + + P + V P +G T+N++ ++ ++L + +
Sbjct: 1722 SAAGWLPSTVRLWKQPVPQPQLEGVLPGSLGG-TDNVDPFEFLGQIQRLSLGVCTPNNLM 1780
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRT 502
VE+TL D NDN PVF P+++ + +++ N G I ++ A D D L +L+ +
Sbjct: 1781 EVEITLQDVNDNPPVF-PNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLLFPSEGP 1839
Query: 503 SNL---TITS----PFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
+ L TI S F+I+P +G + + E R ++L V A D + S+ R ++
Sbjct: 1840 NALVTYTIISGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADDGKQS-SDMRLNIT 1898
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
V I P F A Y F + + G+ V I +D+ +V+Y L
Sbjct: 1899 VKDIN---------DHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLE 1949
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
+E F + +GV V L Y Y Q+ + +V+DVND
Sbjct: 1950 ED-DEDETFLLNPVTGVFNVTRVLD-YELQRYYILTARAQDGGGQASTVRVYFNVLDVND 2007
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
V +S + S G T ++S +G F D
Sbjct: 2008 NPPVFETTTYSASV------SESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGHFL 2061
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I +DG + TQK LDRE + Y + + + QV++ + D ND PP F
Sbjct: 2062 ITKDGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTFTS 2121
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
+I EN+ + T + + A+D+D G N+ Y+L G F + G V+ +
Sbjct: 2122 QKMT-YIQENTPVDTVVLA---VHASDSDSGPNSYVEYSLHGPFSNKFSIGTIDGDVRLV 2177
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
G+ LDRE+ Y L++VA D G LSS ++ +++ D NDN P F+Q
Sbjct: 2178 GE-LDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQ 2224
Score = 135 bits (327), Expect = 8e-30
Identities = 138/530 (26%), Positives = 232/530 (43%), Gaps = 38/530 (7%)
Query: 385 ETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVN 444
ET PS F++S R+ ++ + + + + + + N+ Q
Sbjct: 50 ETKPSFTYRFSESHRLFSING----SSGVISTSAVIDREALQSDVINVVVLSSQPTYPTE 105
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM-------VLY 497
V + +LD NDN+PVF +++ S K +A G + A D D+G NG+ V
Sbjct: 106 VRIVVLDINDNSPVFPDASIV-VSFKEDASSGRQVILDTATDTDIGSNGVDHTTYRIVKG 164
Query: 498 DLQRTSNLTITSPFKINPNT--GTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ QR L IT +NP+ + + + L+ F + + + E + + +
Sbjct: 165 NEQRKFRLDIT----VNPSGEGAFLHLVSTGGLDREVTPFYQLLIEVEDKGEPK-TFGYL 219
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+ VT + P P F Y+ V + +G+S+ Q+ +D E + ++ + +
Sbjct: 220 QVNVTIQDINDNP--PSFERDLYQASVLEDAAVGSSILQVTASDGDEAANA--EIRYFLD 275
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERG 674
E PF ++ ++G I + + L +R Y A+ +LS AT+ ++DVND
Sbjct: 276 EETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEATIKLLDVNDNDP 335
Query: 675 VLLKGAHSPI---IFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD-- 728
V+ K + P V EN+ G + + ++ S NG +V L N+Q +
Sbjct: 336 VV-KFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQRHFEVH 394
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ I LDRE+ Y +TV N ++ + + I++ D ND+PP+F+
Sbjct: 395 TSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDINDHPPIFQ 454
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
Y I E+ G+ IK + ATD D G NA Y+L G F + EN+G+V
Sbjct: 455 ETEYRVDISEDIPKGSYIKG---VSATDGDSGQNANLRYSLVSGNALGWFSISENSGLVT 511
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LDRE L++ A+D G S +LII I D ND P F Q
Sbjct: 512 SAA-LLDREATSEVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQ 560
Score = 127 bits (306), Expect = 3e-27
Identities = 127/477 (26%), Positives = 205/477 (42%), Gaps = 39/477 (8%)
Query: 431 NIEYYDEQL---MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
NI D+ L +S+ + + + D ND P F S + S+ +A GT + + A D
Sbjct: 527 NISAKDQGLQPRISYTKLIINITDVNDQVPTFTQST-FHVSLAEHAPAGTQLLVLSATDG 585
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP 545
DLG NG + + + F+++P +G +S A E + L V+ +D +P
Sbjct: 586 DLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTD-GGSP 644
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQ 603
R VT+ R N+ P F Y V N G+ V + D
Sbjct: 645 PLRSAGKVNVTL---RDVNDNR---PVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRN 698
Query: 604 NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA- 662
V Y + G + F + +G I+ + L R + Y + A + + L T A
Sbjct: 699 GTVKYMITAG--DAATFHINGNTGKISTLVPLDREEKTTYQLQVTA-ADGSGLRSHTPAI 755
Query: 663 -TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
TV V+D D V + +S ++F + G +G + T + NV +LI
Sbjct: 756 VTVSVLDTQDNPPVFSQKGYSFVMF--ENVGVGTVVGTVSATTVDL-----NTNVSYLIT 808
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ D A+ G I P+DRE++ +++ V+A G I+G V I ++D N
Sbjct: 809 S-GDQRGLFAVNSAGQITASSPIDREEQSFHQLKVVA--RAGQITGE--VSVNITVKDLN 863
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DN P F HA +EN G I KA+D DEG N + +Y+L + +F + E
Sbjct: 864 DNAPRFIHAVEHVSAVENWSTGHTIFQ---AKASDPDEGANGVVVYSLKQNPRGLFHIHE 920
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
G++ G Y++ ++A D G +S LI+ + D NDN P F+Q+
Sbjct: 921 KHGLITLTGPL--EVTASSYEVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQL 975
Score = 126 bits (303), Expect = 6e-27
Identities = 135/476 (28%), Positives = 207/476 (43%), Gaps = 43/476 (9%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E L + VNV V L D NDN P+F +N Y F + + G+++G+V A D D G N V
Sbjct: 1054 EPLSASVNVSVILDDVNDNRPLFNSTN-YVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVR 1112
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVA-----ESPILEGRHALF---VEASDQPANPSER 548
Y + F++N TG +S ES + + A+F V +SDQ +
Sbjct: 1113 YTFEMPQ-----PNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRPLK 1167
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--V 606
+ V I+ + P F Y+ V + T + ++ +D E + V
Sbjct: 1168 DQAKVQVYIQDINDNQ------PKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLV 1221
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVH 665
Y + G EEG F ++ SG IT+V L Y + +A+ A LS ++
Sbjct: 1222 QYHVAEGNEEG-QFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSIS 1280
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V+D ND K S + V EN G + + T+ S G + A
Sbjct: 1281 VLDENDNSPSFPK---SSVSVDVLENMRIGELVASVTATDTDS--GPNADITYSITATNN 1335
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
T I+ G+IF K LD E + VY++ V A+ N G S + V I++ D NDNP
Sbjct: 1336 HGTFSIS-PNTGSIFLVKKLDYETQSVYKLNVSAKDN-GRPSRSSSIPVIIHVRDFNDNP 1393
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE--GKEMFDVDEN 842
P+F I EN + T + M I A D D N Y++ + F +D +
Sbjct: 1394 PIFTPGDIFKSIPENLPVATSVMM---IVAHDTDADINGQLEYSIVQQVPRGNHFSIDAS 1450
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG-GLSSE----AELIIMIGDENDNKPEF 893
TGV+ + +DRE +++L++ A D L + + I + D+NDN P F
Sbjct: 1451 TGVL-YTNQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF 1505
Score = 107 bits (256), Expect = 3e-21
Identities = 120/468 (25%), Positives = 197/468 (42%), Gaps = 38/468 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + S + + +T+ D ND++P F + Y F + + G+++ + A D D G NG V
Sbjct: 1886 DGKQSSDMRLNITVKDINDHSPKFSRAT-YSFDIPEDTTAGSIVAAILASDSDSGVNGEV 1944
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLA 553
Y L+ F +NP TG +V L+ + L A D S R
Sbjct: 1945 TYSLEEDDE---DETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGGQASTVRVYFN 2001
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS--YDLL 611
V+ + + P P F Y V ++ G+SV + +DA + + Y +
Sbjct: 2002 VLDVN-------DNP--PVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIA 2052
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDF----EAVALQENANLSIVTNATVHVV 667
G +G F + + G + L R + Y+ +A + +V ++
Sbjct: 2053 SGDPQG-HFLIT-KDGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILL 2110
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
DVND S + +++EN+ + H + S N V + +
Sbjct: 2111 DVNDCPPTFT----SQKMTYIQENTPVDTVVLAVHASDSDSGPNSY--VEYSLHGPFSNK 2164
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I DG + LDRE+ Y +TV+A +KG + VT+ + D NDN P F
Sbjct: 2165 FSIGTI-DGDVRLVGELDREEISNYTLTVVAT-DKGEPPLSSTMDVTMVVLDVNDNTPSF 2222
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
Y+ I EN+ GT++ + ATDADEGTN +++ G + F + TG++
Sbjct: 2223 SQNIYDIEIEENTLTGTDVIQ---VFATDADEGTNGQIRFSISGSNTD-FRIYSVTGMIS 2278
Query: 848 FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ LDRE + Y L + A D G +A + I++ D ND P F
Sbjct: 2279 -VARQLDREARSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVF 2325
Score = 103 bits (246), Expect = 5e-20
Identities = 89/320 (27%), Positives = 142/320 (44%), Gaps = 23/320 (7%)
Query: 82 SVTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTV--- 134
+V VY DVNDN P+F T Y +V E P G + A GP+ + +
Sbjct: 1995 TVRVYFNVLDVNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASG 2054
Query: 135 -PRG-LTIFKDIRAFDRDKPNTPNSDVHYSIVSGND---DGHFALESSHKPVLLLRKVLD 189
P+G I KD + + + +++ ND S+ + ++L V D
Sbjct: 2055 DPQGHFLITKDGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVND 2114
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
++ + + +L +HA D D G + + Y L K FS+ ++
Sbjct: 2115 CPPTFTSQKMTYIQENTPVDTVVL---AVHASDSDSGPNSYVEYSLHGPFSNK-FSIGTI 2170
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G + L ELD + + + + L V A+ P ++ V + +LD+NDN P F +
Sbjct: 2171 DGDVRLVGELDRE-----EISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQN 2225
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVL 369
Y+I I EN G V+QV ATD D+G NG+ + + F I +G ++V Q L
Sbjct: 2226 IYDIEIEENTLTGTDVIQVFATDADEGTNGQIRFSISGSNTDFRIYSVTGMISVARQ--L 2283
Query: 370 DREAHSSLRMKVYAKETNPS 389
DREA SS + V A + S
Sbjct: 2284 DREARSSYSLLVQATDRGSS 2303
Score = 102 bits (244), Expect = 9e-20
Identities = 125/471 (26%), Positives = 193/471 (40%), Gaps = 36/471 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I VK N + + F IPE+ G+ + + A D DSG+NG++ Y +
Sbjct: 1897 ITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLEED----- 1951
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK 1036
+ F++N G V R L E + + L A DGG + V V
Sbjct: 1952 --------DEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGGQASTVRVYFNVL 2003
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
DVND+ PVF+ T Y+ +V E+ + V A+DAD G NA L Y I D F I+
Sbjct: 2004 DVNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGHFLIT 2063
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNG--XXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
G L LDRET+ Y L + D DVND P F +
Sbjct: 2064 K-DGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTFTSQ 2122
Query: 1155 DELLEWKHPEADE--LSNHNFESVMMIPVYKATIEENAPIGTTVA-KVFANDTDFIGNGN 1211
++ D L+ H +S P + P + D +G +
Sbjct: 2123 KMTYIQENTPVDTVVLAVHASDSDSG-PNSYVEYSLHGPFSNKFSIGTIDGDVRLVGELD 2181
Query: 1212 GLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
+ + + G P LSST + + V DV D + P F Y++EIEEN
Sbjct: 2182 REEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVND-----NTPSFSQNIYDIEIEENTL 2236
Query: 1272 APVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
+++ + T+ E N ++R+ I N TD R I G + + R DRE + +Y
Sbjct: 2237 TGTDVIQVFATDADEGTNGQIRFSISGSN-TDFR----IYSVTGMISVARQLDREARSSY 2291
Query: 1330 EVIVRA-ERQKYSRELPHMIYPVAEDVLEGMTKYDVK-VVVRIKDVNDNSP 1378
++V+A +R R + V DV + +++ VR+++ +N P
Sbjct: 2292 SLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLP 2342
Score = 101 bits (243), Expect = 1e-19
Identities = 119/488 (24%), Positives = 215/488 (44%), Gaps = 43/488 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ + ++ V VT+ D NDN P F +LY+ S+ +A VG+ I +V A D D N +
Sbjct: 212 EPKTFGYLQVNVTIQDINDNPPSF-ERDLYQASVLEDAAVGSSILQVTASDGDEAANAEI 270
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y L + PF+I+P TGT+ + E E R ++L + A D R
Sbjct: 271 RYFLDEET------PFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEAT 324
Query: 554 VVTIEVTRGTKGNKPDIP-DFMGAPYEFW-VGSNVGIGTSVGQIRVNDAFEQ---NDVSY 608
+ ++V N P + + +F V N +GT V + V+D+ ++S
Sbjct: 325 IKLLDVN----DNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSAANGNISV 380
Query: 609 DLLHGYEEG---VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNA 662
+L G E+ V + +I V L R Y+ V++ +N S +
Sbjct: 381 SILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNL-TVSVSDNGKPVARSSFASL 439
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ V D+ND + + + I ++ G+ I + T+ S N+R+ + +
Sbjct: 440 VIFVNDINDHPPIFQETEYRVDIS--EDIPKGSYIKGVSATDGDS---GQNANLRYSLVS 494
Query: 723 QQDVTDDIAIAEDGTIFTQKPL-DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ +I+E+ + T L DRE + + A+ ++G+ ++ I I D N
Sbjct: 495 G-NALGWFSISENSGLVTSAALLDREATSEVVLNISAK-DQGLQPRISYTKLIINITDVN 552
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMF 837
D P F +T+ + E++ GT++ ++ ATD D G N ++ E + F
Sbjct: 553 DQVPTFTQSTFHVSLAEHAPAGTQLL---VLSATDGDLGPNGTMRFSFDAETPAAAQGRF 609
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+D +G + + LDRE++ Y L + D G L S ++ + + D NDN+P F
Sbjct: 610 RLDPLSGRLSTAVE-LDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYP 668
Query: 896 IEENSKVR 903
++ + V+
Sbjct: 669 LQYFANVK 676
Score = 100 bits (239), Expect = 4e-19
Identities = 170/738 (23%), Positives = 294/738 (39%), Gaps = 90/738 (12%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q+ V+V +T+ D NDN P F+ + + S N G I + KA DPD G NG+V+Y
Sbjct: 848 QITGEVSVNITVKDLNDNAPRFIHA-VEHVSAVENWSTGHTIFQAKASDPDEGANGVVVY 906
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
L++ F I+ G +++ P+ + VE + + SL ++
Sbjct: 907 SLKQNPR----GLFHIHEKHGLITLT-GPLEVTASSYEVEVIAEDMGVPKHTSSLVLIV- 960
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYE 615
+ P F YE + + + + ++ D ++ YD+ G
Sbjct: 961 ----SVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGG-N 1015
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERG 674
G F + G + + +L R + Y+ VA LS N +V + DVND R
Sbjct: 1016 TGDVFGIFP-DGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRP 1074
Query: 675 VLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ + +FH +E G+ +G++F + +G + VR+ Q + AI
Sbjct: 1075 LFNSTNY---VFHFEEEQQRGSLVGRVFAEDKD--FGPNS-EVRYTFEMPQPNFELNAIT 1128
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G + + DRE R GA ++ + D+ P+ + A +
Sbjct: 1129 --GELSSTAQFDRESLMRQR-------------GAAVFSFVVVSSDQGLPRPLKDQAKVQ 1173
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN-TGVVKFIGDS 852
+I + + + D + +A+ ++ N + + DVDEN G+V++
Sbjct: 1174 VYIQDINDNQPKFTKD-VYQASVSESAPNVTQLLRVSAS-----DVDENKNGLVQYHVAE 1227
Query: 853 LDREKKIMY-----KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+ E + M +++LV + +S L I+ D +P + + + I
Sbjct: 1228 GNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVD-GGAEP----LSSSCMLSISVL 1282
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
+ + + F PK+ ++DV EN+ IG + + A D DSG N I
Sbjct: 1283 DENDNSPSF------PKSSVSVDV---------LENMRIGELVASVTATDTDSGPNADIT 1327
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG-- 1023
Y S A F I+ G + + + L E++ ++LN+SA D G
Sbjct: 1328 Y-------------SITATNNHGTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRP 1374
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY- 1082
+ + +I V + V+D ND+ P+F ++ E + + A D D N L Y
Sbjct: 1375 SRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYS 1434
Query: 1083 FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG--XXXXXXXXXXXXXX 1140
+Q F I TGVL N E+DRE + + LTV A D
Sbjct: 1435 IVQQVPRGNHFSIDASTGVLYTNQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIW 1494
Query: 1141 XXDVNDNSPKFYAFDELL 1158
D NDN P F + + L+
Sbjct: 1495 VTDQNDNIPTFLSQNALV 1512
Score = 98.7 bits (235), Expect = 1e-18
Identities = 134/483 (27%), Positives = 196/483 (40%), Gaps = 65/483 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+IP G+ I ++A D DSG N +RY S +S +AL +F I+E G
Sbjct: 462 ISEDIPKGSYIKGVSATDGDSGQNANLRY----------SLVSGNALG---WFSISENSG 508
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVR---VFVKDVNDHFPVFKKTWYNFNV 1054
V A L E SE LNISA D G L IS + + DVND P F ++ ++ ++
Sbjct: 509 LVTSAALLDREATSEVVLNISAKDQG-LQPRISYTKLIINITDVNDQVPTFTQSTFHVSL 567
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRE 1111
E L + ATD D G N + + P+ F + PL+G LS ELDRE
Sbjct: 568 AEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAVELDRE 627
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+ Y+L V D G DVNDN P FY K
Sbjct: 628 EQASYLLHVQVTDGG-SPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVK---------E 677
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFAND-TDFIGNGN-GLILYSLP---QRKNQQN 1226
N S + AT + GT + A D F NGN G I +P + K
Sbjct: 678 NEPSGSYVTTVSATDPDLGRNGTVKYMITAGDAATFHINGNTGKISTLVPLDREEKTTYQ 737
Query: 1227 LGLPSLSSTAILMVTVADVPDEV--EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
L + + + + T A V V + PVF + Y + ENV + +++ T
Sbjct: 738 LQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTV 797
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
N + Y I D R F ++ G + DRE + +++ V A
Sbjct: 798 DLNTNVSYLI---TSGDQRGLFAVNSA-GQITASSPIDREEQSFHQLKVVAR-------- 845
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
G +V V + +KD+NDN+P+F + V+A+ + G+ + Q
Sbjct: 846 ------------AGQITGEVSVNITVKDLNDNAPRFIHAVEH-VSAVENWST-GHTIFQA 891
Query: 1405 KGA 1407
K +
Sbjct: 892 KAS 894
Score = 96.7 bits (230), Expect = 4e-18
Identities = 122/503 (24%), Positives = 205/503 (40%), Gaps = 59/503 (11%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSE 973
I+ V N + DQL LIPE+ P+ + K+ A D DSG NG+I Y+ +
Sbjct: 959 IVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGGNTGD 1018
Query: 974 VY--IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISV 1031
V+ P +L A E+ R I ER+ V+VAR E L+ +++V
Sbjct: 1019 VFGIFPDGQLYIKA-ELDRE--IQERYNLVLVARDRAVEP-------------LSASVNV 1062
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
V + DVND+ P+F T Y F+ EE Q ++G+V A D DFG N+ + Y + +
Sbjct: 1063 SVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQPN- 1121
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
FE++ +T GEL + + + R G + K
Sbjct: 1122 -FELNAIT------GELSSTAQ--FDRESLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKV 1172
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
+ + + P+ + VY+A++ E+AP T + +V A+D D N N
Sbjct: 1173 QVYIQDINDNQPKFTK------------DVYQASVSESAPNVTQLLRVSASDVD--ENKN 1218
Query: 1212 GLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD---------EVEMSDKPVFISRYY 1262
GL+ Y + + N++ + SS I +V D V+ +P+ S
Sbjct: 1219 GLVQYHVAE-GNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCML 1277
Query: 1263 ELEI-EENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
+ + +EN N+P S + EN ++ + + TD D
Sbjct: 1278 SISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHG 1337
Query: 1322 DREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ I ++ Y + + + A+D + V++ ++D NDN P FT
Sbjct: 1338 TFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFT 1397
Query: 1382 NGNRPLVTAIPTTAPFGYQVMQL 1404
G+ + +IP P VM +
Sbjct: 1398 PGD--IFKSIPENLPVATSVMMI 1418
Score = 94.7 bits (225), Expect = 2e-17
Identities = 69/215 (32%), Positives = 105/215 (48%), Gaps = 10/215 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALE-VKRYFVINERH 998
I EN+ G I++L A D D L F SE P + ++ + F I+
Sbjct: 1805 IEENVGDGFKIMQLTATDADE-LPYVSWLLFPSEG--PNALVTYTIISGADDSFRIDPES 1861
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G +I + L E S++ L + A DG +D + + + VKD+NDH P F + Y+F++ E
Sbjct: 1862 GDLIATKKLDRERRSKYSLLVRADDGKQSSD-MRLNITVKDINDHSPKFSRATYSFDIPE 1920
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
++ + A+D+D G N +TY ++ D D F ++P+TGV +V LD E + Y
Sbjct: 1921 DTTAGSIVAAILASDSDSGVNGEVTYSLEEDDEDETFLLNPVTGVFNVTRVLDYELQRYY 1980
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
ILT A+D G DVNDN P F
Sbjct: 1981 ILTARAQDGG---GQASTVRVYFNVLDVNDNPPVF 2012
Score = 91.1 bits (216), Expect = 2e-16
Identities = 116/439 (26%), Positives = 185/439 (42%), Gaps = 34/439 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V +LD NDN PVF + Y S+ + G+ + V A D D G N + Y
Sbjct: 1994 STVRVYFNVLDVNDNPPVF-ETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFY--- 2049
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
R ++ F I + G + ++ E + + L + +D P R S A V++
Sbjct: 2050 RIASGDPQGHFLITKD-GNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVI 2108
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
+ + D P + ++ N + T V + +D+ + V Y L HG
Sbjct: 2109 LL-----DVNDCPPTFTSQKMTYIQENTPVDTVVLAVHASDSDSGPNSYVEYSL-HGPFS 2162
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGV 675
F++ G + +V +L R Y VA + LS + T+ V+DVND
Sbjct: 2163 N-KFSIGTIDGDVRLVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPS 2221
Query: 676 LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIA 733
+ + ++EN+ G + Q+F T+ GT G +RF I+ TD +
Sbjct: 2222 FSQNIYD---IEIEENTLTGTDVIQVFATDADE----GTNGQIRFSISGSN--TDFRIYS 2272
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I + LDRE R Y + V A ++G V I + D ND PVFE + Y
Sbjct: 2273 VTGMISVARQLDREARSSYSLLVQAT-DRGSSPRMDQATVNIVLLDVNDCAPVFELSPYT 2331
Query: 794 GFIMEN-SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ EN + T + + A D D+G N Y L G G + ++G + +
Sbjct: 2332 VRVQENLENLPTNVLQ---VVARDDDQGANGQLSYMLSG-GNDDGAFSLSSGGQLRLTQT 2387
Query: 853 LDREKKIMYKLSLVARDTG 871
+DRE + Y L + A D+G
Sbjct: 2388 VDREARGEYILLITATDSG 2406
Score = 90.2 bits (214), Expect = 4e-16
Identities = 110/463 (23%), Positives = 196/463 (42%), Gaps = 39/463 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V+V + D NDN P F ++Y+ S+ +A T + +V A D D +NG+V Y + +
Sbjct: 1172 VQVYIQDINDNQPKFT-KDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAEGNE 1230
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I+ ++G +++ E ++L + A D A P L++ ++
Sbjct: 1231 ---EGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVLD---- 1283
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
N P P + V N+ IG V + D D++Y + G F
Sbjct: 1284 ENDNSPSFPK---SSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGT-F 1339
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV--HVVDVNDERGVLLK 678
++ +G I +V L + +Y V+ ++N S ++ V HV D ND +
Sbjct: 1340 SISPNTGSIFLVKKLDYETQSVYKLN-VSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFTP 1398
Query: 679 GAHSPIIFHVKENS--AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AED 735
G I + EN A + + + H + I G + + I Q + +I A
Sbjct: 1399 G---DIFKSIPENLPVATSVMMIVAHDTDADI----NGQLEYSIVQQVPRGNHFSIDAST 1451
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA--GIYQVTIYIEDENDNPPVFEHATYE 793
G ++T + +DRE +++ +TV A + + VTI++ D+NDN P F +
Sbjct: 1452 GVLYTNQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF--LSQN 1509
Query: 794 GFIME-NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ E N IG+ + + A D DEG N Y L F +D +G ++
Sbjct: 1510 ALVAEPNIMIGSIL---TTVVAYDPDEGANGEVEYELVEGDSGTFIMDRYSGDIRLASQL 1566
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ +++Y L++ A D G + + I + + P F+Q
Sbjct: 1567 V--PSQLVYSLTVSATDHGTERKTSRTDLTIILQGLDGPVFSQ 1607
Score = 89.4 bits (212), Expect = 7e-16
Identities = 65/177 (36%), Positives = 97/177 (54%), Gaps = 13/177 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G +R+ ISG++ F + SV G + + ++LD +A +++ L VQ
Sbjct: 2244 VFATDADEGTNGQIRFS-ISGSNTD-FRIYSVTGMISVARQLDREAR-----SSYSLLVQ 2296
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN-GFSVLQVMATDKDQG 336
A+ + + QA V I LLD+ND P FE+ Y + + ENL N +VLQV+A D DQG
Sbjct: 2297 ATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVLQVVARDDDQG 2356
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
NG+ +Y L + GAFS+ SG QTV DREA + + A ++ SV+
Sbjct: 2357 ANGQLSYMLSGGNDDGAFSLS--SGGQLRLTQTV-DREARGEYILLITATDSGTSVL 2410
Score = 87.0 bits (206), Expect = 3e-15
Identities = 154/626 (24%), Positives = 257/626 (41%), Gaps = 98/626 (15%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY--QVTIYIEDENDNPPVFEHATYE 793
G I T +DRE + VI N V+S Y +V I + D NDN PVF A+
Sbjct: 73 GVISTSAVIDRE---ALQSDVI---NVVVLSSQPTYPTEVRIVVLDINDNSPVFPDASIV 126
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
E++ G ++ +D ATD D G+N G + + + KF D
Sbjct: 127 VSFKEDASSGRQVILDT---ATDTDIGSN--------GVDHTTYRIVKGNEQRKFRLDIT 175
Query: 854 DREKKIMYKLSLVARDTGGLSSEA----ELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
L LV+ TGGL E +L+I + D+ + K F ++ N ++
Sbjct: 176 VNPSGEGAFLHLVS--TGGLDREVTPFYQLLIEVEDKGEPKT-FGYLQVNVTIQD----- 227
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
I P + F D+ Q L E+ +G++I+++ A D D N +IRY
Sbjct: 228 ---------INDNPPS-FERDLYQASVL----EDAAVGSSILQVTASDGDEAANAEIRYF 273
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NL 1025
+ E P F I+ + G +I+ L ES E+ L I A+D G +L
Sbjct: 274 LDEET---P-------------FQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSL 317
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWY----NF-NVEEAQYTRRVLGKVDATDADFGQ-NAN 1079
+ + + DVND+ PV K ++ F +V+E V+ + +D+D N N
Sbjct: 318 SGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSAANGN 377
Query: 1080 LTYFIQPSDTDLPFEIS----PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
++ I + FE+ P ++ V LDRE Y LTV DNG
Sbjct: 378 ISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSSFA 437
Query: 1136 XXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTT 1195
D+ND+ P F + E++ ++++ ++ + + +NA + +
Sbjct: 438 SLVIFVNDINDHPPIF----QETEYRVDISEDIPKGSY--IKGVSATDGDSGQNANLRYS 491
Query: 1196 VAKVFANDTDFIGNGNGLIL-YSLPQRK---------NQQNLGLPSLSSTAILMVTVADV 1245
+ A I +GL+ +L R+ + ++ GL S L++ + DV
Sbjct: 492 LVSGNALGWFSISENSGLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDV 551
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIR 1303
D+V P F + + + E+ A +L+ L+ T+ N MR+ E +
Sbjct: 552 NDQV-----PTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAAQ 606
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTY 1329
F +DP +G L DRE + +Y
Sbjct: 607 GRFRLDPLSGRLSTAVELDREEQASY 632
Score = 87.0 bits (206), Expect = 3e-15
Identities = 83/323 (25%), Positives = 144/323 (44%), Gaps = 19/323 (5%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTI 130
G+ + ++ L + V + DVNDN P+F Y V + E P + F G + I
Sbjct: 948 GVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEI 1007
Query: 131 PLTVPRGLT-----IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ G T IF D + + + + + + + ++ D L +S ++L
Sbjct: 1008 VYDIAGGNTGDVFGIFPDGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSVILD 1067
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
V D V ++ ++ + A D+D G + +RY F
Sbjct: 1068 DVNDNRPLFNSTNYVFHFEEEQQRGSLV--GRVFAEDKDFGPNSEVRYTFEMPQPN--FE 1123
Query: 246 LDSVNGSLFLEKELDLDA---EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
L+++ G L + D ++ + +FV+ L PLK QA+V++ + D+NDN
Sbjct: 1124 LNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRPLKD-QAKVQVYIQDINDN 1182
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P+F D Y S+ E+ PN +L+V A+D D+ +NG Y + + +G F ID SG
Sbjct: 1183 QPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAEGNEEGQFMIDSSSGQ 1242
Query: 361 LTVRNQTVLDREAHSSLRMKVYA 383
+T+ + LD E SS +K+ A
Sbjct: 1243 ITLVGK--LDYETTSSYSLKIIA 1263
Score = 85.8 bits (203), Expect = 8e-15
Identities = 89/353 (25%), Positives = 148/353 (41%), Gaps = 26/353 (7%)
Query: 50 QNVVKFRLGCDFDEGDDLVRIGA--GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVD 107
Q +K L + E +LV + + +SA ++V+V ++DVNDN P+F T Y +
Sbjct: 1027 QLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTNYVFHFE 1086
Query: 108 ELTPTGEKAF-IFLI-APIGPSLTIPLTVPRGLTIFK---------DIRAFDRDKPNTPN 156
E G +F GP+ + T F+ FDR+
Sbjct: 1087 EEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQPNFELNAITGELSSTAQFDRESLMRQR 1146
Query: 157 SDVHYS-IVSGNDDG-HFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILF 214
+S +V +D G L+ K + ++ + D K + V AS +
Sbjct: 1147 GAAVFSFVVVSSDQGLPRPLKDQAKVQVYIQDINDNQP--KFTKDVYQASVSESAPNVTQ 1204
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D ++Y + GN+ F +DS +G + L +LD + + +
Sbjct: 1205 LLRVSASDVDENKNGLVQYHVAEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAV 1264
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A L++ + I +LD NDN P F ++ ++EN+ G V V ATD D
Sbjct: 1265 DGGAEPLSS-----SCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTD 1319
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G N + TY + + G FSI P +G + + + LD E S ++ V AK+
Sbjct: 1320 SGPNADITYSITATNNHGTFSISPNTGSIFLVKK--LDYETQSVYKLNVSAKD 1370
Score = 81.8 bits (193), Expect = 1e-13
Identities = 102/400 (25%), Positives = 168/400 (42%), Gaps = 52/400 (13%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ V V ++D+ND+ P F++ Y +V E + +V A+D D NA + YF+ D
Sbjct: 219 LQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTASDGDEAANAEIRYFL---D 275
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
+ PF+I P TG + + LD E+ +Y LT+ A DNG DVNDN
Sbjct: 276 EETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNG-VPSLSGRAEATIKLLDVNDND 334
Query: 1149 P--KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV-----AKVFA 1201
P KF F K DE + ++ + N I ++ + F
Sbjct: 335 PVVKFRYFPTTS--KFASVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQRHFE 392
Query: 1202 NDTDFIGNGNGLILYSLPQRK--NQQNL-------GLP-SLSSTAILMVTVADVPDEVEM 1251
T + N + + + S+ R+ + NL G P + SS A L++ V D+ D
Sbjct: 393 VHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDINDH--- 449
Query: 1252 SDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVID 1309
P+F Y ++I E++ + ++ VS + +N +RY +++ N F I
Sbjct: 450 --PPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNALG---WFSIS 504
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVR 1369
+G + DRE T EV++ + + P + Y K+++
Sbjct: 505 ENSGLVTSAALLDREA--TSEVVLNISAKDQGLQ-PRISY--------------TKLIIN 547
Query: 1370 IKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIG 1409
I DVND P FT ++ AP G Q++ L G
Sbjct: 548 ITDVNDQVPTFTQST--FHVSLAEHAPAGTQLLVLSATDG 585
Score = 81.4 bits (192), Expect = 2e-13
Identities = 89/338 (26%), Positives = 149/338 (44%), Gaps = 43/338 (12%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPI-----FLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
G+ +S T+ + DVNDN P+ F T +VDE G + ++ S
Sbjct: 313 GVPSLSGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSS 372
Query: 128 LT---IPLTVPRG---------------LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDD 169
I +++ G L++ K DR++ ++ N V S D+
Sbjct: 373 AANGNISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVS-----DN 427
Query: 170 GHFALESSHKP-VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVG 228
G SS V+ + + D+ +E + + S + I K + + + A D D G
Sbjct: 428 GKPVARSSFASLVIFVNDINDHPPIFQETEYRVDIS-EDIPKGS-YIKGVSATDGDSGQN 485
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A LRY L+SGN FS+ +G + LD +A + VL + A + +
Sbjct: 486 ANLRYSLVSGNALGWFSISENSGLVTSAALLDREATSEV-----VLNISAKDQGLQPRIS 540
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG--EFTYQLD 346
++ I + D+ND +P F +++S+ E+ P G +L + ATD D G NG F++ +
Sbjct: 541 YTKLIINITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAE 600
Query: 347 DP---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
P +G F +DP SG L+ + LDRE +S + V
Sbjct: 601 TPAAAQGRFRLDPLSGRLSTAVE--LDREEQASYLLHV 636
Score = 80.2 bits (189), Expect = 4e-13
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 28/326 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTI 130
GL +Y + + I DVND VP F + +HV++ E P G + + +GP+ T+
Sbjct: 534 GLQPRISYTKLIINITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTM 593
Query: 131 PLTVPRGLTIFKDIR------------AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
+ R A + D+ + +H + G G L S+
Sbjct: 594 RFSFDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDG---GSPPLRSAG 650
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISG 238
K + LR V D + L A+ K + + A D DLG T++Y +I+
Sbjct: 651 KVNVTLRDV--NDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKY-MITA 707
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
D F ++ G + LD + + T+ LQV A+ + A V + +LD
Sbjct: 708 GDAATFHINGNTGKISTLVPLDRE-----EKTTYQLQVTAADGSGLRSHTPAIVTVSVLD 762
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
DN P F Y+ + EN+ G V V AT D N + D +G F+++ +
Sbjct: 763 TQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQRGLFAVN-SA 821
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAK 384
G +T + +DRE S ++KV A+
Sbjct: 822 GQITA--SSPIDREEQSFHQLKVVAR 845
Score = 79.4 bits (187), Expect = 7e-13
Identities = 58/171 (33%), Positives = 84/171 (49%), Gaps = 10/171 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y + + N+ FS+ GS+FL K+LD + + + + L V
Sbjct: 1313 VTATDTDSGPNADITYSITATNNHGTFSISPNTGSIFLVKKLDYETQ-----SVYKLNVS 1367
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P +++ V I + D NDN P F SI ENLP SV+ ++A D D
Sbjct: 1368 AKDNGRPSRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADI 1427
Query: 338 NGEFTYQL--DDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG+ Y + P+G FSID +G L NQ V DRE + + V A +
Sbjct: 1428 NGQLEYSIVQQVPRGNHFSIDASTGVL-YTNQEV-DREFSNLFELTVKATD 1476
Score = 78.6 bits (185), Expect = 1e-12
Identities = 93/377 (24%), Positives = 152/377 (40%), Gaps = 50/377 (13%)
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS------ 607
++ +E+T + P P F + + NVG G + Q+ DA E VS
Sbjct: 1779 LMEVEITLQDVNDNP--PVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLLFPS 1836
Query: 608 --------YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV 659
Y ++ G ++ F ++ SG + L R R Y A + +
Sbjct: 1837 EGPNALVTYTIISGADDS--FRIDPESGDLIATKKLDRERRSKYSLLVRADDGKQSSDMR 1894
Query: 660 TNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRF 718
N TV D+ND + +S F + E++ AG+ + I ++ S G V +
Sbjct: 1895 LNITVK--DINDHSPKFSRATYS---FDIPEDTTAGSIVAAILASDSDS---GVNGEVTY 1946
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ + + G + LD E + Y +T A+ G S +Y +
Sbjct: 1947 SLEEDDEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGGQASTVRVY---FNVL 2003
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKE 835
D NDNPPVFE TY + E+ G+ + + A+DAD+G NA Y + +G
Sbjct: 2004 DVNDNPPVFETTTYSASVSESLPAGSSVV---TVVASDADDGPNAQLFYRIASGDPQGHF 2060
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG-----GLSSEAELIIMIGDENDNK 890
+ D N K +LDRE + Y L + D +S A++ +++ D ND
Sbjct: 2061 LITKDGNLRTQK----ALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCP 2116
Query: 891 PEFNQ-----IEENSKV 902
P F I+EN+ V
Sbjct: 2117 PTFTSQKMTYIQENTPV 2133
Score = 77.0 bits (181), Expect = 4e-12
Identities = 65/193 (33%), Positives = 92/193 (47%), Gaps = 23/193 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT +I++ A D D G NGQIR+ +S + + Y V G
Sbjct: 2231 IEENTLTGTDVIQVFATDADEGTNGQIRFS-----------ISGSNTDFRIYSVT----G 2275
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ VAR L E S + L + A D G+ D +V + + DVND PVF+ + Y V+
Sbjct: 2276 MISVARQLDREARSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQ 2335
Query: 1056 E--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E VL +V A D D G N L+Y + + D F +S G L + +DRE
Sbjct: 2336 ENLENLPTNVL-QVVARDDDQGANGQLSYMLSGGNDDGAFSLSS-GGQLRLTQTVDREAR 2393
Query: 1114 DKYILTVVARDNG 1126
+YIL + A D+G
Sbjct: 2394 GEYILLITATDSG 2406
Score = 74.5 bits (175), Expect = 2e-11
Identities = 81/316 (25%), Positives = 136/316 (43%), Gaps = 24/316 (7%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA--PIG 125
+++ A QI+ +SV + ++D+NDN P F+ HV+ E TG F + G
Sbjct: 840 LKVVARAGQITGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHTIFQAKASDPDEG 899
Query: 126 PSLTIPLTV---PRGL-TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
+ + ++ PRGL I + P + + V D G + +
Sbjct: 900 ANGVVVYSLKQNPRGLFHIHEKHGLITLTGPLEVTASSYEVEVIAEDMG---VPKHTSSL 956
Query: 182 LLLRKVLDYDAGDKEF-QL---VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
+L+ V D + F QL V++ + ++ + A D+D G + Y++
Sbjct: 957 VLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFF---KVEATDKDSGFNGEIVYDIAG 1013
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN +F + +G L+++ ELD +Q ++ V + PL +A V + L
Sbjct: 1014 GNTGDVFGI-FPDGQLYIKAELD----REIQERYNLVLVARDRAVEPL-SASVNVSVILD 1067
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
D+NDN P F Y E G V +V A DKD G N E Y + P+ F ++
Sbjct: 1068 DVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQPNFELNAI 1127
Query: 358 SGWLTVRNQTVLDREA 373
+G L+ Q DRE+
Sbjct: 1128 TGELSSTAQ--FDRES 1141
Score = 73.7 bits (173), Expect = 3e-11
Identities = 76/294 (25%), Positives = 119/294 (40%), Gaps = 31/294 (10%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL----TIPLTVPRG- 137
V V + DVNDN P+F Y V E P+G +++ ++ P L T+ + G
Sbjct: 652 VNVTLRDVNDNRPVFYPLQYFANVKENEPSG--SYVTTVSATDPDLGRNGTVKYMITAGD 709
Query: 138 ---LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
I + P Y + DG SH P ++ VLD
Sbjct: 710 AATFHINGNTGKISTLVPLDREEKTTYQLQVTAADGSGL--RSHTPAIVTVSVLDTQDNP 767
Query: 195 KEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
F +M + + + A DL + Y + SG+ R LF+++S
Sbjct: 768 PVFSQKGYSFVMFENVGVGTVV---GTVSATTVDLNTNVS--YLITSGDQRGLFAVNSA- 821
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + +D + + Q +A Q+ T + V I + DLNDN P F
Sbjct: 822 GQITASSPIDREEQSFHQLKVVA---RAGQI-----TGEVSVNITVKDLNDNAPRFIHAV 873
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTV 363
++S VEN G ++ Q A+D D+G NG Y L +P+G F I + G +T+
Sbjct: 874 EHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSLKQNPRGLFHIHEKHGLITL 927
Score = 70.1 bits (164), Expect = 4e-10
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 11/172 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D DLG T+R+ + F LD ++G L ELD + + + ++L
Sbjct: 580 LSATDGDLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAVELDREEQAS-----YLL 634
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
VQ + +P + +V + L D+NDN P F Y ++ EN P+G V V ATD D
Sbjct: 635 HVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPD 694
Query: 335 QGENGEFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG Y + A F I+ +G + LDRE ++ +++V A +
Sbjct: 695 LGRNGTVKYMITAGDAATFHINGNTG--KISTLVPLDREEKTTYQLQVTAAD 744
Score = 68.5 bits (160), Expect = 1e-09
Identities = 59/210 (28%), Positives = 104/210 (49%), Gaps = 20/210 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S ++V + +LD NDN P F N+Y+ ++ N GT + +V A D D G NG + +
Sbjct: 2202 LSSTMDVTMVVLDVNDNTPSF-SQNIYDIEIEENTLTGTDVIQVFATDADEGTNGQIRFS 2260
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ ++ + F+I TG +SVA E R ++L V+A+D+ ++P + ++ +V
Sbjct: 2261 ISGSN-----TDFRIYSVTGMISVARQLDREARSSYSLLVQATDRGSSPRMDQATVNIVL 2315
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNV-GIGTSVGQI--RVNDAFEQNDVSYDLLHG 613
++V P F +PY V N+ + T+V Q+ R +D +SY L G
Sbjct: 2316 LDV-------NDCAPVFELSPYTVRVQENLENLPTNVLQVVARDDDQGANGQLSYMLSGG 2368
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMY 643
++G F++ G + + + R R Y
Sbjct: 2369 NDDGA-FSLSS-GGQLRLTQTVDREARGEY 2396
Score = 66.1 bits (154), Expect = 7e-09
Identities = 89/356 (25%), Positives = 136/356 (38%), Gaps = 26/356 (7%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
L T L++ T F + V T + + S V V LLD ND P F +
Sbjct: 2068 LRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTFTSQKM--T 2125
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
++ N V TV+ V A D D G N V Y L ++ F I G V +
Sbjct: 2126 YIQENTPVDTVVLAVHASDSDSGPNSYVEYSLHG----PFSNKFSIGTIDGDVRLVGELD 2181
Query: 528 LE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + L V A+D+ P + +V ++V T P F Y+ + N
Sbjct: 2182 REEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNT-------PSFSQNIYDIEIEEN 2234
Query: 586 VGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
GT V Q+ DA E N + G F + +G+I+V L R R Y
Sbjct: 2235 TLTGTDVIQVFATDADEGTNGQIRFSISG--SNTDFRIYSVTGMISVARQLDREARSSYS 2292
Query: 645 FEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
V + + + ATV++V DVND V SP V+EN +
Sbjct: 2293 L-LVQATDRGSSPRMDQATVNIVLLDVNDCAPVF---ELSPYTVRVQENLENLPTNVLQV 2348
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA 758
G G + ++++ D +++ G + + +DRE R Y + + A
Sbjct: 2349 VARDDDQG-ANGQLSYMLSGGND-DGAFSLSSGGQLRLTQTVDREARGEYILLITA 2402
Score = 63.3 bits (147), Expect = 5e-08
Identities = 49/168 (29%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + Y L N R LF + +G + L L++ A +++ ++V A
Sbjct: 893 ASDPDEGANGVVVYSL-KQNPRGLFHIHEKHGLITLTGPLEVTA------SSYEVEVIAE 945
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ P T+ + + + D+NDN P F+ Y + I E+ P +V ATDKD G NG
Sbjct: 946 DMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNG 1005
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
E Y + + F I P G L ++ + LDRE + + A++
Sbjct: 1006 EIVYDIAGGNTGDVFGIFP-DGQLYIKAE--LDREIQERYNLVLVARD 1050
Score = 54.8 bits (126), Expect = 2e-05
Identities = 49/146 (33%), Positives = 66/146 (45%), Gaps = 21/146 (14%)
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF----------- 1074
N+ + V + ++DVND+ PVF + +EE + ++ ATDAD
Sbjct: 1777 NNLMEVEITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLLFPS 1836
Query: 1075 -GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
G NA +TY I S D F I P +G L +LDRE KY L V A D
Sbjct: 1837 EGPNALVTYTII-SGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADDG----KQSS 1891
Query: 1134 XXXXXXXXXDVNDNSPKF----YAFD 1155
D+ND+SPKF Y+FD
Sbjct: 1892 DMRLNITVKDINDHSPKFSRATYSFD 1917
Score = 44.4 bits (100), Expect = 0.024
Identities = 47/184 (25%), Positives = 81/184 (44%), Gaps = 43/184 (23%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG+ + ++ + +T+ DV D + PVF + ++ IEENV +++ L T+
Sbjct: 1770 SLGVCTPNNLMEVEITLQDVND-----NPPVFPNDILDVTIEENVGDGFKIMQLTATDAD 1824
Query: 1286 E--------------NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
E N + Y I++ D R IDP +G L + DRE + Y +
Sbjct: 1825 ELPYVSWLLFPSEGPNALVTYTIISGADDSFR----IDPESGDLIATKKLDRERRSKYSL 1880
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
+VRA+ +G D+++ + +KD+ND+SPKF+
Sbjct: 1881 LVRAD--------------------DGKQSSDMRLNITVKDINDHSPKFSRATYSFDIPE 1920
Query: 1392 PTTA 1395
TTA
Sbjct: 1921 DTTA 1924
Score = 44.0 bits (99), Expect = 0.032
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
+LFS++ +G + +D +A LQ++ + V +SQ P + V I +LD+ND
Sbjct: 64 RLFSINGSSGVISTSAVIDREA---LQSDVINVVVLSSQPTYPTE-----VRIVVLDIND 115
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
N P F +S E+ +G V+ ATD D G NG
Sbjct: 116 NSPVFPDASIVVSFKEDASSGRQVILDTATDTDIGSNG 153
Score = 44.0 bits (99), Expect = 0.032
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 18/183 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D A +RY L ++ F +D G++ +++ LD ++ + L +
Sbjct: 257 VTASDGDEAANAEIRYFL---DEETPFQIDPKTGTIIIKEGLDYESRRE-----YSLTIH 308
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-----ISIVENLPNGFSVLQVMATD 332
A P + +A I+LLD+NDN P + ++ S+ EN G V + +D
Sbjct: 309 AVDNGVPSLSGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSD 368
Query: 333 KD-QGENGEFTYQL--DDPKGAFSI--DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
D NG + + + + F + P ++ +VLDRE SS + V +
Sbjct: 369 SDSSAANGNISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNG 428
Query: 388 PSV 390
V
Sbjct: 429 KPV 431
Score = 39.5 bits (88), Expect = 0.69
Identities = 53/206 (25%), Positives = 84/206 (40%), Gaps = 14/206 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLI-API 124
+V G +S+ + VT+ + DVNDN P F Y + ++E T TG +F A
Sbjct: 2192 VVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENTLTGTDVIQVFATDADE 2251
Query: 125 GPSLTIPLTVPRGLTIFK-----DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
G + I ++ T F+ + + R S YS++ D +
Sbjct: 2252 GTNGQIRFSISGSNTDFRIYSVTGMISVARQLDREARSS--YSLLVQATDRGSSPRMDQA 2309
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI--DQDLGVGATLRYELIS 237
V ++ +LD + F+L + + E L + + D D G L Y L
Sbjct: 2310 TVNIV--LLDVNDCAPVFELSPYTVRVQENLENLPTNVLQVVARDDDQGANGQLSYMLSG 2367
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDA 263
GND FSL S G L L + +D +A
Sbjct: 2368 GNDDGAFSLSS-GGQLRLTQTVDREA 2392
>UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1677
Score = 166 bits (403), Expect = 5e-39
Identities = 204/755 (27%), Positives = 317/755 (41%), Gaps = 83/755 (10%)
Query: 410 TNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSM 469
T PL++ T F T T+ LM + + +T+LD ND+ PVF N Y S+
Sbjct: 160 TKKPLDRETTDFYQLNITATDR---GTPALMGYCLINITILDENDHAPVFT-QNSYLGSI 215
Query: 470 KSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE 529
N K G I +V A D D G NG + Y + + + S F ++ +TG + ++ E
Sbjct: 216 AENTKPGVSILRVSAADRDSGSNGDIKYAIDWDA-IQSNSIFDLDSSTGVIRTKQNLDFE 274
Query: 530 GRHALF--VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPY---EFWVGS 584
+++ V ASD PS+ LA VTI V T N P + P+ +
Sbjct: 275 VKNSYTFNVIASDGGV-PSKN--DLATVTINVL-DTNDNSPQLKITYLPPHNGDKAIRSE 330
Query: 585 NVGIGTSVGQIRVNDAFEQNDVSYDL--LHGYEEGVPFAVEERSGV-ITVVDDLSRYNRP 641
N I T++ I V D + +L +G +EG F VE I + L R P
Sbjct: 331 NSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGC-FKVEFLGFYFIQLQKPLDRELVP 389
Query: 642 MYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
Y+ + + S + + V DVND A++ I + +N G+ + Q+
Sbjct: 390 FYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQN--GSYVLQL 447
Query: 701 FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF 760
T+ G V + I D+ + G + T KPLDRE+ +T+ A+
Sbjct: 448 NATDPDE---GDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQ- 503
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ G G VT+ I D NDN P F ++Y+G I E + IG + + ATD D G
Sbjct: 504 DHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQ---VSATDVDSG 560
Query: 821 TNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI 880
N Y + ++ + E L+ + +++ S + R+T L S
Sbjct: 561 DNGRITYEISSSDAQVNGLFE-----------LNTQTGVLWTKSQLDRETKSLYS---FT 606
Query: 881 IMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLI 940
++ D D Q+ + KV + TI ++ V+ +
Sbjct: 607 VLAKDHGDP-----QLMSSVKVEL------------TISDINDNAPVFYPVEYFASIM-- 647
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
EN P G ++++ A D D G N I Y+ I + + F I+ G
Sbjct: 648 -ENEPPGK-LLQVTATDADEGTNAVISYD------IIGGNNNGN-------FSIDSSTGV 692
Query: 1001 VIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ SL E E F L ISA DGGN V V V + D+ PVF YNF V E
Sbjct: 693 ISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYE 752
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
++G+V AT D +N +++Y I D F + G++ +NG++DRE + +Y
Sbjct: 753 NVPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQY 810
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+L V+AR G D NDN+P+F
Sbjct: 811 LLAVIAR-VGTVKPLSAQATVNIEVLDRNDNAPQF 844
Score = 140 bits (338), Expect = 4e-31
Identities = 184/703 (26%), Positives = 295/703 (41%), Gaps = 83/703 (11%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
++V+V + D NDN P F P+ Y ++ + V T A DPD G NG V Y +
Sbjct: 79 ISVQVQVDDINDNEPRF-PTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASG 137
Query: 503 SN-LTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVTI 557
N T + P T+ V L+ + L + A+D+ P+ Y L +TI
Sbjct: 138 DNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDR-GTPALMGYCLINITI 196
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDL-LHGY 614
P F Y + N G S+ ++ D+ D+ Y +
Sbjct: 197 ------LDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAI 250
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
+ F ++ +GVI +L + Y F +A + + + T++V+D ND
Sbjct: 251 QSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTND-N 309
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY-----GNGTGNVRFLIANQQDV-T 727
LK + P H + A + + +TN++ I N I N D
Sbjct: 310 SPQLKITYLPP--H-NGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGC 366
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I QKPLDRE Y +T+ +KGV S + + V I + D NDN P F
Sbjct: 367 FKVEFLGFYFIQLQKPLDRELVPFYNLTLNVT-DKGVPSRSTLGFVLIDVTDVNDNSPAF 425
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--FDVDENTGV 845
Y I E ++ G+ + + ATD DEG N Y++ G G ++ F VD +G+
Sbjct: 426 TSNAYTANISELAQNGSYVLQ---LNATDPDEGDNGTVSYSITG-GNDLGWFQVDFQSGL 481
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEFNQIEENSKVR 903
V LDRE+ +++ A+D G + + + I D NDNKP F ++ + K
Sbjct: 482 VT-TAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRF--MKSSYKGT 538
Query: 904 IHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
I + G T+++V A DVD +N G ++++ D+ +N
Sbjct: 539 ISE----GASIGATVLQVS-----ATDVDS-------GDN---GRITYEISS--SDAQVN 577
Query: 964 GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG 1023
G + V S+L + + + V+ + HG + S+ E L IS
Sbjct: 578 GLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVE----LTIS----- 628
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
D+ND+ PVF Y ++ E + ++L +V ATDAD G NA ++Y
Sbjct: 629 -------------DINDNAPVFYPVEYFASIMENEPPGKLL-QVTATDADEGTNAVISYD 674
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
I + + F I TGV+S LD E E+ + L + A+D G
Sbjct: 675 IIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGG 717
Score = 137 bits (332), Expect = 2e-30
Identities = 195/729 (26%), Positives = 303/729 (41%), Gaps = 100/729 (13%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
VN+EV LD NDN P F S++ + VG V+ AVD D G+NG+V Y L T
Sbjct: 830 VNIEV--LDRNDNAPQFSTSSVI-VDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQL--T 884
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEG---RHALFVEASDQPANPSERRYSLAVVTIEV 559
SN IN +G + +A + +G ++ + V ASD + P + +TI +
Sbjct: 885 SNAE--GLLWINSTSGVIKLARK-LTDGDETQYTVQVLASDSGSPPQH-----STMTIHI 936
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
T N P P F + Y V ++ + + D+ + + Y + G EEG
Sbjct: 937 TLSI--NHP--PKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEG 992
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
+ F + G + + L + + YD A + S T+++ D ND R +
Sbjct: 993 L-FGIFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLF 1050
Query: 677 LKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ F V ENS+ G +G + + + V LI+++ D+
Sbjct: 1051 VNNTFR---FAVAENSSPGTLVGTLVAHALD--HSRTKDIVYSLISSESHFAVDV---RS 1102
Query: 736 GTIFTQKPLDREK------RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G I T+ LDRE+ +VY M A +N I V + + D NDN PVF
Sbjct: 1103 GQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAI-VIVTVTDLNDNAPVFSR 1161
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKF 848
A Y + E S G+ + IKA DADEG NA F Y+L G G + F ++ +TG +
Sbjct: 1162 AVYAITVSELSLPGSPVFR---IKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGEL-H 1217
Query: 849 IGDSLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ +LDRE Y L + A D L S A++ I +GD ND +P F E + V I
Sbjct: 1218 LSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFP--ESDYTVNITE 1275
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
+ + G +I + +K D+ Q G LI +I G D++S G++
Sbjct: 1276 DALI----GSLVINLNASDK---DIGQNG---LIKYSISNGNLAA---MFDVESA-TGRL 1321
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLN 1026
I L + ++ + + HG +P S + ++ LD +N
Sbjct: 1322 ---------IVAKSLDFETTQLYELTITAQDHG------LIPLSSTVNVTVNVLD---VN 1363
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
DN P+F V E T +G+ A+D D G NA++ + +
Sbjct: 1364 DNA-------------PLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYS 1410
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRET----EDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
F ++ T ++ +D ET D + L V+A D G
Sbjct: 1411 QTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQG-SPKLSTRKSITVQVT 1469
Query: 1143 DVNDNSPKF 1151
D NDNSP F
Sbjct: 1470 DENDNSPGF 1478
Score = 121 bits (292), Expect = 1e-25
Identities = 121/465 (26%), Positives = 218/465 (46%), Gaps = 37/465 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ FV ++VT D NDN+P F SN Y ++ A+ G+ + ++ A DPD G NG V Y +
Sbjct: 408 LGFVLIDVT--DVNDNSPAFT-SNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSI 464
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
++L F+++ +G V+ A+ E ++ + + Q + + S VT+ +
Sbjct: 465 TGGNDL---GWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGS-TTVTVTI 520
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEE- 616
G NKP FM + Y+ + IG +V Q+ D + + ++Y++ +
Sbjct: 521 IDGND-NKPR---FMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQV 576
Query: 617 -GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDER 673
G+ F + ++GV+ L R + +Y F +A +++ + ++++ V + D+ND
Sbjct: 577 NGL-FELNTQTGVLWTKSQLDRETKSLYSFTVLA-KDHGDPQLMSSVKVELTISDINDNA 634
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV-RFLIANQQDVTDDIAI 732
V + I EN + Q+ T+ GT V + I + +
Sbjct: 635 PVFYPVEYFASIM---ENEPPGKLLQVTATDADE----GTNAVISYDIIGGNNNGNFSID 687
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G I T LD E + + + + A+ + G A V + + ++ DN PVF + Y
Sbjct: 688 SSTGVISTLASLDHEVEEFFSLIISAK-DGGNKYAAKTAVVNVTVLNKADNLPVFLYEMY 746
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+ EN GT + + AT D+ N Y + G+ +F VD G++K GD
Sbjct: 747 NFTVYENVPKGTLVGR---VYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGIIKINGD 801
Query: 852 SLDREKKIMYKLSLVAR--DTGGLSSEAELIIMIGDENDNKPEFN 894
+DRE+K Y L+++AR LS++A + I + D NDN P+F+
Sbjct: 802 -MDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFS 845
Score = 111 bits (267), Expect = 1e-22
Identities = 118/439 (26%), Positives = 186/439 (42%), Gaps = 45/439 (10%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
T GF +I+V N + I E G+ +++LNA D D G NG + Y
Sbjct: 407 TLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITG 466
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNL--NDN 1028
+ L +F ++ + G V A+ L E S + I+A D G+ +
Sbjct: 467 G-----NDLG--------WFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGS 513
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+V V + D ND+ P F K+ Y + E + +V ATD D G N +TY I SD
Sbjct: 514 TTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSD 573
Query: 1089 TDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ FE++ TGVL +LDRET+ Y TV+A+D+G D+ND
Sbjct: 574 AQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHG-DPQLMSSVKVELTISDIND 632
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N+P FY + A + N ++ + A NA I + N
Sbjct: 633 NAPVFYPVEYF-------ASIMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFS 685
Query: 1207 IGNGNGLI--LYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
I + G+I L SL + ++ G + TA++ VTV + D + PV
Sbjct: 686 IDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNL-----PV 740
Query: 1257 FISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
F+ Y + ENV + + T +N + Y I++ + T++ F++D G +
Sbjct: 741 FLYEMYNFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSGDPTNL---FLVDSTGGIIK 797
Query: 1317 LVRSPDREVKDTYEVIVRA 1335
+ DRE K Y + V A
Sbjct: 798 INGDMDREEKAQYLLAVIA 816
Score = 108 bits (260), Expect = 1e-21
Identities = 206/884 (23%), Positives = 353/884 (39%), Gaps = 117/884 (13%)
Query: 41 DSLVDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPI 96
+S+ D DS V++ + DF+ + +++ G+ + +VT+ + D NDN P
Sbjct: 253 NSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSP- 311
Query: 97 FLDTPYHVTVDELTP-TGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTP 155
+ + L P G+KA + I ++ L DK +
Sbjct: 312 ------QLKITYLPPHNGDKAIRSENSLINTNIAYILVT---------------DKDSNT 350
Query: 156 NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP 215
NS I +G+D+G F +E + L+K LD + LV +
Sbjct: 351 NSQTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRE-------LVPF-----------YN 392
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
++ D+ + +TL + LI D + N F + Q ++VLQ
Sbjct: 393 LTLNVTDKGVPSRSTLGFVLIDVTDV------NDNSPAFTSNAYTANISELAQNGSYVLQ 446
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP---NGFSVLQVMATD 332
+ A+ +P + V + ND L F+VDF + + P S + + T
Sbjct: 447 LNAT---DPDEGDNGTVSYSITGGND-LGWFQVDFQSGLVTTAKPLDREQVSSVTITITA 502
Query: 333 KDQG---ENGEFTYQL-----DDPKGAFSIDPRSGWL--------TVRNQTVLDREAHSS 376
+D G + G T + +D K F G + TV + D ++ +
Sbjct: 503 QDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDN 562
Query: 377 LRMKVYAKETNPSVVGTFA-DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYY 435
R+ ++ V G F ++Q W + L+ K+ Y F V K ++
Sbjct: 563 GRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRET---KSLYSFT--VLAK----DHG 613
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D QLMS V VE+T+ D NDN PVF P Y S+ N G ++ +V A D D G N ++
Sbjct: 614 DPQLMSSVKVELTISDINDNAPVFYPVE-YFASIMENEPPGKLL-QVTATDADEGTNAVI 671
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLA 553
YD+ +N F I+ +TG +S S +E +L + A D +Y+
Sbjct: 672 SYDIIGGNN---NGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKD-----GGNKYAAK 723
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+ VT K + ++P F+ Y F V NV GT VG++ + +SY ++ G
Sbjct: 724 TAVVNVTVLNKAD--NLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSG 781
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
+ F V+ G+I + D+ R + Y +A LS + V+D ND
Sbjct: 782 DPTNL-FLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDN 840
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + S +I + +GQ +++ + G VR+ + + + I
Sbjct: 841 AP---QFSTSSVIVDI---DGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWIN 894
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G I + L Y + V+A + G S +TI+I ++PP F ++
Sbjct: 895 -STSGVIKLARKLTDGDETQYTVQVLAS-DSG--SPPQHSTMTIHITLSINHPPKFTLSS 950
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y ++ + + + + A D D G N Y++ +G E G +I
Sbjct: 951 YVTHVLASQPLSYQF---FYVVAVDQDSGKNGQLFYSI-PQGNEEGLFGIFPGGKLYIRK 1006
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
SL + K Y L + A D G S+ + I I D ND++ F
Sbjct: 1007 SLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLF 1050
Score = 100 bits (239), Expect = 4e-19
Identities = 121/494 (24%), Positives = 215/494 (43%), Gaps = 46/494 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VT+ D NDN PVF + +Y ++ + G+ + ++KA+D D G N Y L +
Sbjct: 1145 VIVTVTDLNDNAPVFSRA-VYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTG 1203
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F IN +TG + ++++ E + L V+A+D + YS A IE+T G
Sbjct: 1204 M---DKFFINSSTGELHLSKTLDRETTSSYNLVVKATDAS---NANLYSTA--KIEITVG 1255
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDLLHGYEEGVPF 620
++ P F + Y + + IG+ V + +D QN + Y + +G + F
Sbjct: 1256 DSNDQR--PVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAM-F 1312
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
VE +G + V L +Y+ A LS N TV+V+DVND +
Sbjct: 1313 DVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLF--- 1369
Query: 680 AHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIAEDGT 737
P+ V+EN + G +G+ ++ + GT ++ F + +Q +
Sbjct: 1370 PTQPVTLTVRENVNTGFPVGRCTASDRDT----GTNAHIAFSMYSQTPSKTFSVNSATCE 1425
Query: 738 IFTQKPLDREK----RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
I T +D E RD +++ V+A ++G + +T+ + DENDN P
Sbjct: 1426 ITTIAAIDLETMPAGRDSFQLVVMAT-DQGSPKLSTRKSITVQVTDENDNSP-------- 1476
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
GF+ + I A D D +N Y++ F++ +TG ++ I
Sbjct: 1477 GFVSPPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIP 1536
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDEN--DNKPEFNQIEENSKVRIHRETKLN 911
D +Y+L++ A D G S + + ++ + E P F+ + V E K+
Sbjct: 1537 D--NPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSV---TENKVA 1591
Query: 912 GTAGFTIIEVKPKN 925
GT+ T++ P++
Sbjct: 1592 GTSVVTVLAAYPQS 1605
Score = 87.4 bits (207), Expect = 3e-15
Identities = 112/461 (24%), Positives = 188/461 (40%), Gaps = 39/461 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +E+T+ D+ND PVF P + Y ++ +A +G+++ + A D D+GQNG++ Y
Sbjct: 1244 LYSTAKIEITVGDSNDQRPVF-PESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYS 1302
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ SN + + F + TG + VA+S E + L + A D P ++ V
Sbjct: 1303 I---SNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNV 1359
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYE 615
++V + P F P V NV G VG+ +D + ++
Sbjct: 1360 LDV-------NDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQT 1412
Query: 616 EGVPFAVEERSGVITVVD--DLSRYNRPMYDFEAVAL---QENANLSIVTNATVHVVDVN 670
F+V + IT + DL F+ V + Q + LS + TV V D N
Sbjct: 1413 PSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDEN 1472
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D +SP +AG+++ + N G V + I + + ++
Sbjct: 1473 D---------NSPGFVSPPAAAAGSSL-NVMTITAEDPDRNSNGKVTYSIISGNNGYFNL 1522
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ + D +Y++T+ A + G S V+++ E P F A
Sbjct: 1523 HPSTGQLQMIHQIPDNP--TIYQLTIQAS-DGGQPSRQTQTVVSVFKEGPIGGGPTFSSA 1579
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y+G + EN GT + ++ A + Y K F+V ++TGVVK
Sbjct: 1580 DYQGSVTENKVAGTSVV--TVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVK-TT 1636
Query: 851 DSLDRE-KKIMYKLSLVARDTGGLS---SEAELIIMIGDEN 887
+DRE + L + A D G S S A + I + D N
Sbjct: 1637 RGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677
Score = 80.6 bits (190), Expect = 3e-13
Identities = 71/260 (27%), Positives = 113/260 (43%), Gaps = 22/260 (8%)
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIH-AIDQDLGVGATLR 232
L S++P+ + +V D + + F + R ++ PI+ A D D G T+
Sbjct: 72 LNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVD 131
Query: 233 YELISGNDRKLFSLDSV----NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
Y + SG++ FSL + +L + + LD E + + L + A+ P
Sbjct: 132 YTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRE---TTDFYQLNITATDRGTPALMG 188
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-- 346
+ I +LD ND+ P F + Y SI EN G S+L+V A D+D G NG+ Y +D
Sbjct: 189 YCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWD 248
Query: 347 --DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWR 404
F +D +G +R + LD E +S V A + G +A
Sbjct: 249 AIQSNSIFDLDSSTG--VIRTKQNLDFEVKNSYTFNVIASD------GGVPSKNDLATVT 300
Query: 405 RQPLET--NAPLEKTTYVFP 422
L+T N+P K TY+ P
Sbjct: 301 INVLDTNDNSPQLKITYLPP 320
Score = 77.4 bits (182), Expect = 3e-12
Identities = 101/421 (23%), Positives = 164/421 (38%), Gaps = 45/421 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++ + TT A D D+G NG + Y S L A
Sbjct: 104 IRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLC------ 157
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
VI + L E+ ++LNI+A D G L + + + D NDH PVF + Y ++
Sbjct: 158 -VITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIA 216
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + +V A D D G N ++ Y I ++ F++ TGV+ LD E +
Sbjct: 217 ENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK 276
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+ Y V+A D G D NDNSP+ + + P + + +
Sbjct: 277 NSYTFNVIASDGG-VPSKNDLATVTINVLDTNDNSPQL-----KITYLPPHNGDKAIRSE 330
Query: 1174 ESVM--MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK--------- 1222
S++ I T +++ T K+ D + L Y + +K
Sbjct: 331 NSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPF 390
Query: 1223 -----NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
N + G+PS S+ +++ V DV D + P F S Y I E ++
Sbjct: 391 YNLTLNVTDKGVPSRSTLGFVLIDVTDVND-----NSPAFTSNAYTANISELAQNGSYVL 445
Query: 1278 SLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
LN T+ E N + Y I ND F +D ++G + + DRE + + + A
Sbjct: 446 QLNATDPDEGDNGTVSYSITGGNDLG---WFQVDFQSGLVTTAKPLDREQVSSVTITITA 502
Query: 1336 E 1336
+
Sbjct: 503 Q 503
Score = 74.5 bits (175), Expect = 2e-11
Identities = 68/283 (24%), Positives = 119/283 (42%), Gaps = 17/283 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPLTVPRGLTI 140
V V + D+NDN P+F Y +TV EL+ G F + A G + ++ G +
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGM 1204
Query: 141 FK-----DIRAFDRDKPNTPNSDVHYS-IVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
K K + Y+ +V D + L S+ K + + D
Sbjct: 1205 DKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVF 1264
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
E + + + ++ ++A D+D+G ++Y + +GN +F ++S G L
Sbjct: 1265 PESDYTVNITEDALIGSLVIN--LNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLI 1322
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
+ K LD + Q + Q L PL + V + +LD+NDN P F ++
Sbjct: 1323 VAKSLDFETT---QLYELTITAQDHGLI-PLSST-VNVTVNVLDVNDNAPLFPTQPVTLT 1377
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
+ EN+ GF V + A+D+D G N + + P FS++
Sbjct: 1378 VRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVN 1420
Score = 73.7 bits (173), Expect = 3e-11
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 9/170 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D D G A Y L+SG F ++S G L L K LD + +++ L V+
Sbjct: 1181 IKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRET-----TSSYNLVVK 1235
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +N + A++EI + D ND P F Y ++I E+ G V+ + A+DKD G+
Sbjct: 1236 ATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQ 1295
Query: 338 NGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y + + A F ++ +G L V LD E + + A++
Sbjct: 1296 NGLIKYSISNGNLAAMFDVESATGRLIVAKS--LDFETTQLYELTITAQD 1343
Score = 68.1 bits (159), Expect = 2e-09
Identities = 49/158 (31%), Positives = 77/158 (48%), Gaps = 7/158 (4%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAE-HNLQANTFVLQVQASQLNNPLKTAQAR 291
Y LIS F++D +G + LD + N +N +++Q +A + +K +A
Sbjct: 1087 YSLISSESH--FAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAI 1144
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG- 350
V + + DLNDN P F Y I++ E G V ++ A D D+G+N +F Y L G
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGM 1204
Query: 351 -AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
F I+ +G L + LDRE SS + V A + +
Sbjct: 1205 DKFFINSSTGELHL--SKTLDRETTSSYNLVVKATDAS 1240
Score = 59.7 bits (138), Expect = 6e-07
Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 7/168 (4%)
Query: 990 RYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
+ F N G + + E+ ++++ N ISV+V V D+ND+ P F +
Sbjct: 40 KQFGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLY 99
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS----PLTGVLSV- 1104
Y + E+ ATD D G N + Y I D F + P L V
Sbjct: 100 YTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVI 159
Query: 1105 -NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRET D Y L + A D G D ND++P F
Sbjct: 160 TKKPLDRETTDFYQLNITATDRG-TPALMGYCLINITILDENDHAPVF 206
Score = 59.7 bits (138), Expect = 6e-07
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 12/155 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA--NTFVLQVQ 277
A+DQD G L Y + GN+ LF + G L++ K L LQA ++ L V+
Sbjct: 970 AVDQDSGKNGQLFYSIPQGNEEGLFGIFP-GGKLYIRKSL-------LQALKGSYDLIVR 1021
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P +A V I + D ND+ F + + ++ EN G V ++A D
Sbjct: 1022 ATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSR 1081
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ Y L + F++D RSG +T R + LDRE
Sbjct: 1082 TKDIVYSLISSESHFAVDVRSGQITTRVR--LDRE 1114
Score = 55.6 bits (128), Expect = 1e-05
Identities = 65/294 (22%), Positives = 119/294 (40%), Gaps = 19/294 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRG-LT 139
+ + + D ND P+F ++ Y V + E G + IG + I ++ G L
Sbjct: 1250 IEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLA 1309
Query: 140 IFKDI-----RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
D+ R + + ++ ++ D G L S+ V + VLD +
Sbjct: 1310 AMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSST---VNVTVNVLDVNDNA 1366
Query: 195 KEFQLVIMASGKRIHKEILFPEP-IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
F + R + FP A D+D G A + + + S K FS++S +
Sbjct: 1367 PLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEI 1426
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
+DL+ ++F L V A+ +P + + + +++ D NDN P F
Sbjct: 1427 TTIAAIDLETMP-AGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFV-----S 1480
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQ 366
+ +V+ + A D D+ NG+ TY + G F++ P +G L + +Q
Sbjct: 1481 PPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQ 1534
Score = 52.8 bits (121), Expect = 7e-05
Identities = 88/330 (26%), Positives = 129/330 (39%), Gaps = 39/330 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVT----------VDELTP----TGEKAFI 118
GL +S+ ++VTV + DVNDN P+F P +T V T TG A I
Sbjct: 1345 GLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHI 1404
Query: 119 -FLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS 177
F + PS T +V I A D + D +V D G L S+
Sbjct: 1405 AFSMYSQTPSKTF--SVNSATCEITTIAAIDLETMPA-GRDSFQLVVMATDQGSPKL-ST 1460
Query: 178 HKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
K + + +V D + F A+G ++ + E D D + Y +I
Sbjct: 1461 RKSITV--QVTDENDNSPGFVSPPAAAAGSSLNVMTITAE-----DPDRNSNGKVTYSII 1513
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
SGN+ F+L G L + ++ + + L +QAS P + Q V +
Sbjct: 1514 SGNNG-YFNLHPSTGQLQMIHQIPDNP------TIYQLTIQASDGGQPSRQTQTVVSVFK 1566
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
P F Y S+ EN G SV+ V+A NG Y L D KG F +
Sbjct: 1567 EGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEV 1626
Query: 355 DPRSGWLTVRNQTVLDREA-HSSLRMKVYA 383
+G V+ +DRE +S + VYA
Sbjct: 1627 VKSTG--VVKTTRGIDREGMGASFNLVVYA 1654
Score = 41.9 bits (94), Expect = 0.13
Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 20/193 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN+P GT + ++ A D NG I Y S P+ L F+++
Sbjct: 748 FTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSG---DPTNL----------FLVDST 792
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + + + E +++ L + A G L+ +V + V D ND+ P F + +
Sbjct: 793 GGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVD 852
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
++ +V+ A D D G+N + Y + + L + I+ +GV+ + +L E
Sbjct: 853 IDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLW-INSTSGVIKLARKLTDGDE 911
Query: 1114 DKYILTVVARDNG 1126
+Y + V+A D+G
Sbjct: 912 TQYTVQVLASDSG 924
Score = 40.3 bits (90), Expect = 0.40
Identities = 38/159 (23%), Positives = 58/159 (36%), Gaps = 4/159 (2%)
Query: 991 YFVINERHGHVIVARSLPPESE-FRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKK 1047
YF ++ G + + +P ++L I A DGG + V VF + P F
Sbjct: 1519 YFNLHPSTGQLQMIHQIPDNPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSS 1578
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y +V E + + V A N N+ Y++ + FE+ TGV+
Sbjct: 1579 ADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTTRG 1638
Query: 1108 LDRE-TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+DRE + L V A D DVN
Sbjct: 1639 IDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677
>UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome shotgun
sequence; n=11; Clupeocephala|Rep: Chromosome 1
SCAF13750, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 4362
Score = 165 bits (401), Expect = 8e-39
Identities = 220/932 (23%), Positives = 397/932 (42%), Gaps = 82/932 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+N+ + +LD NDN PVF ++Y S+ NA+ GT++ ++ A D D G NG + Y +T
Sbjct: 2794 LNLTIEVLDTNDNRPVF-SKDIYLVSLDENAQRGTLVVQLNATDLDEGLNGEIEYSFGKT 2852
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVT 560
+ F+++ TG + V + E L ++ASD+ P S V+ I
Sbjct: 2853 QKKKVQDTFELDSVTGEIRVKGNVDFEETEVFRLDIQASDKGHLPWTAE-SRVVIKI--- 2908
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ N+P+I V + GT + I + D + + ++ ++ VPF
Sbjct: 2909 KDINDNRPEIEI---TSLSTSVPEDAKPGTVISLISIRD--KDSGLNGKVICKISGDVPF 2963
Query: 621 ----AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGV 675
++EE + L R YD A + LS V + TV+V DVND R V
Sbjct: 2964 DLTPSIEENMYSLVTKGRLDRERVAHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPV 3023
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIAI- 732
+ ++ V+ N+ GA+I + + + N N + + D+T + I
Sbjct: 3024 FNQNPFE--LYLVENNAPGASIFSVSAVD-DDLNENALVNYNIIRGDGLLNDLTAFLNIN 3080
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+E+G I K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 3081 SENGQISALKSFDFETLKTFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILYPVS 3139
Query: 793 EGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVK 847
E +I + ++ ++A DAD G N ++ L +F +D TG ++
Sbjct: 3140 SNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIR 3199
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV--RIH 905
+ S + +KL ++ +D G +S A +++ + ++P+ N + ++ +
Sbjct: 3200 TL-RSFTETDETEHKLVILVKDNGNVSLSATATVLV--KLHHRPDCNAVSKSPDYTSKYV 3256
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
ET +GT +I ++ L +GP I I G+ N L L
Sbjct: 3257 PETNYDGTLCHSIQYRSGDKRYML----VGPRMSIGSTIVPGS---HANTLVLPD----- 3304
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG 1023
R N E + K + H+++ + L E + L ++ALDGG
Sbjct: 3305 -RRRTNEEGSHRCECIWLIQFLKKVIKTGDRTSAHLVLQKQLDREKQDVISLTLTALDGG 3363
Query: 1024 N--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
N + + + V D+ND+ PVF ++ Y + E + ++ATD D NA +
Sbjct: 3364 NPPKSGTSQIIISVLDINDNAPVFSRSLYKAQIPENIQAGTTVIVLNATDEDKELNAEIE 3423
Query: 1082 YFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
+ ++ +D F I P +G + VNG++D E + + A D G
Sbjct: 3424 FSLRSKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKG-QPPMSTDCKVL 3482
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK 1198
DVNDN+P+ LL +A+ + ++ ++ V +N + +A
Sbjct: 3483 VEVLDVNDNAPEI-TVTPLLSTVKEDAEVGT-----AIALVSVLDKDGGKNGIVRAAIAN 3536
Query: 1199 --VFANDTDFIGNGNGLILYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPD 1247
F DT++ N L++ R++Q G P LSST+ + V V+DV D
Sbjct: 3537 HVPFKLDTNY-KNYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVND 3595
Query: 1248 EVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTD--IR 1303
+ P F+ + + ++EN V A ++ ++ + ++ ++RY L N +
Sbjct: 3596 -----NAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSESQPLS 3650
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
I+ G + ++S D E T++ V+A
Sbjct: 3651 SMININSETGDIVSLQSFDYEELKTFQFQVQA 3682
Score = 113 bits (271), Expect = 5e-23
Identities = 115/459 (25%), Positives = 211/459 (45%), Gaps = 36/459 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ +++T+LD NDN PVF + Y ++ N+ +GT + +V A D D G NG V+Y
Sbjct: 1376 MTIKITVLDVNDNMPVFAKES-YVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNN 1434
Query: 503 SNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
N + F+I+ +TG + + + I ++ R+ + ++ASD+ + P E S+ + +++
Sbjct: 1435 VNHRLRKLFEIDADTGEI-IVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDL 1493
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P+I + V + GT+V I V+D + + V+ ++ E VP
Sbjct: 1494 ----NDNAPEIE---VTSFSKAVPEDSKPGTTVALISVSD--KDSGVNGKVICFINEDVP 1544
Query: 620 FAVEE--RSGVITVVDD--LSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERG 674
F + ++ + +VV L R + YD A + LS +V V DVND
Sbjct: 1545 FMLSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSP 1604
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI---ANQ-QDVTDDI 730
+ +P F+V EN+ +F + + + I NQ Q +T +
Sbjct: 1605 EFVT---NPYTFYVTENNDPGT--TLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFL 1659
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I +E+G I K D E + +++ V+A + G S + V ++I D+NDN PV +
Sbjct: 1660 NINSENGQISALKSFDFEAQKMFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILY 1718
Query: 790 ATYEGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTG 844
E +I + ++ ++A DAD G N ++ L +F +D TG
Sbjct: 1719 PVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 1778
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ + S + +KL ++ +D G +S A +++
Sbjct: 1779 QIRTL-RSFTETDEAEHKLVILVKDNGNVSLSATATVLV 1816
Score = 113 bits (271), Expect = 5e-23
Identities = 115/459 (25%), Positives = 211/459 (45%), Gaps = 36/459 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ +++T+LD NDN PVF + Y ++ N+ +GT + +V A D D G NG V+Y
Sbjct: 2130 MTIKITVLDVNDNMPVFAKES-YVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNN 2188
Query: 503 SNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
N + F+I+ +TG + + + I ++ R+ + ++ASD+ + P E S+ + +++
Sbjct: 2189 VNHRLRKLFEIDADTGEI-IVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDL 2247
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P+I + V + GT+V I V+D + + V+ ++ E VP
Sbjct: 2248 ----NDNAPEIE---VTSFSKAVPEDSKPGTTVALISVSD--KDSGVNGKVICFINEDVP 2298
Query: 620 FAVEE--RSGVITVVDD--LSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERG 674
F + ++ + +VV L R + YD A + LS +V V DVND
Sbjct: 2299 FMLSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSP 2358
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI---ANQ-QDVTDDI 730
+ +P F+V EN+ +F + + + I NQ Q +T +
Sbjct: 2359 EFVT---NPYTFYVTENNDPGT--TLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFL 2413
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I +E+G I K D E + +++ V+A + G S + V ++I D+NDN PV +
Sbjct: 2414 NINSENGQISALKSFDFEAQKMFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILY 2472
Query: 790 ATYEGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTG 844
E +I + ++ ++A DAD G N ++ L +F +D TG
Sbjct: 2473 PVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2532
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ + S + +KL ++ +D G +S A +++
Sbjct: 2533 QIRTL-RSFTETDEAEHKLVILVKDNGNVSLSATATVLV 2570
Score = 110 bits (264), Expect = 3e-22
Identities = 170/725 (23%), Positives = 304/725 (41%), Gaps = 73/725 (10%)
Query: 218 IHAIDQDLGVGATLRYELISG--ND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D+D + A + + L S ND LF +D +G++ + ++D + + F +
Sbjct: 3409 LNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAILVNGKIDYE-----ENPAFEI 3463
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
QAS P + +V +E+LD+NDN PE V ++ E+ G ++ V DKD
Sbjct: 3464 HAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKEDAEVGTAIALVSVLDKD 3523
Query: 335 QGENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYA-KETNPSVVG 392
G+NG + + F +D + ++ LDRE+ + + + A E P +
Sbjct: 3524 GGKNGIVRAAIANHV-PFKLDTNYKNYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSS 3582
Query: 393 TFADSQRIAKWRRQPLETNAP--LEKTTYVFPDK---VGTKTENIEYYDEQLMSFVNVEV 447
T + +++ + NAP LE+ ++ + VG + I D + V
Sbjct: 3583 TSTVAVQVSD-----VNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRY 3637
Query: 448 TLLDAN-DNNPVFVPSNLYE-----FSMKS--NAKVGTVIGKVKAVD---PDLGQNGMV- 495
+ L N ++ P+ N+ S++S ++ T +V+A D P L N V
Sbjct: 3638 SYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVSVN 3697
Query: 496 LYDL-QRTSNLTITSPFKINPNTGTVSVAESPILEG--------RHALFV-EASDQPANP 545
++ L + +N I +P+ + + T E ++E RH + V E S N
Sbjct: 3698 VFILDENDNNPAILAPYSEHGSVNTTVSIEVVVVESGADIQTPFRHNVPVKEESFSDLNL 3757
Query: 546 SERRYSLAVVTIEVTR-----GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
+AV I + + ++ D + Y+ + N GT+V + D
Sbjct: 3758 YLLIAIVAVSAIFLLSLITLIAVRCHRTDGGLGSRSLYKAQIPENTQAGTTVIVLNATDE 3817
Query: 601 FEQ--NDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN- 655
++ ++ + L + V F ++ +SG I V + P ++ A A +
Sbjct: 3818 DKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPP 3877
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTG 714
+S V V+DVND + + ++ VKE++ G AI + + G G
Sbjct: 3878 MSTDCKVLVEVLDVNDNAPEITV---TSLLSTVKEDAEVGTAIALVSVLDKD---GGKNG 3931
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
VR IAN D ++ LDRE + + +T++A ++G + V
Sbjct: 3932 IVRAAIANHVPFKLDTNYKNYYSLVVNGALDRESQAQFNVTIVA-CDEGAPPLSSTSTVA 3990
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDN P F ++ ENS +G +K I A DAD + Y+
Sbjct: 3991 VQVSDVNDNAPRFLEQAINIYVKENSPVGATMKT---ITAVDADVDQSGQVRYSYLQSNS 4047
Query: 835 E------MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
E M +++ TG + + S D E+ ++ + A D+G LSS + + I DE
Sbjct: 4048 ESQPLSSMININSETGDIVSL-QSFDYEELKTFQFQVQATDSGVPPLSSNVSVNVFILDE 4106
Query: 887 NDNKP 891
NDN P
Sbjct: 4107 NDNNP 4111
Score = 109 bits (262), Expect = 6e-22
Identities = 136/486 (27%), Positives = 218/486 (44%), Gaps = 50/486 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQN 492
L S V V+V +LD NDN PV V SN ++ N G ++ KV+A D D+G N
Sbjct: 2450 LSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYN 2509
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRY 550
G +L+ LQ S+ ++ F ++ TG + S E H L + D
Sbjct: 2510 GWLLFALQEVSDHSL---FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATA 2566
Query: 551 SLAVVTIEVTR------------GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN 598
++ V +E G +G P+ + E +G VG SV +
Sbjct: 2567 TVLVKLVEPKEAFAASDCSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVG---SVAKDLGL 2623
Query: 599 DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
D D + ++ G + F + + +GV+ V ++ R + D V L NL I
Sbjct: 2624 DISTLADRRFRIVPGPNHHL-FQLNQDNGVLYVGKNIDR--EELCDGTKVCL---INLKI 2677
Query: 659 VTNATVHVVDVNDERGVLLKGAHS-PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
V + + + V E + A S P E + G F + + T VR
Sbjct: 2678 VVESPLEIHYVGVEIADVNDHAPSFPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVR 2737
Query: 718 FLIANQQDVTD-DIAIAEDGTI---FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ D D DI +E+ I +KPLDRE++ + +T+ A + G S +G +
Sbjct: 2738 SYKLSHNDCFDIDIRESEEDKIPFLVLKKPLDREQKAQHSLTLTA-LDGGNPSRSGSLNL 2796
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
TI + D NDN PVF Y + EN++ GT + + ATD DEG N Y+ FG+
Sbjct: 2797 TIEVLDTNDNRPVFSKDIYLVSLDENAQRGTLVVQ---LNATDLDEGLNGEIEYS-FGKT 2852
Query: 834 -----KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDE 886
++ F++D TG ++ G ++D E+ +++L + A D G L ++E+ ++I I D
Sbjct: 2853 QKKKVQDTFELDSVTGEIRVKG-NVDFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDI 2911
Query: 887 NDNKPE 892
NDN+PE
Sbjct: 2912 NDNRPE 2917
Score = 101 bits (242), Expect = 2e-19
Identities = 93/313 (29%), Positives = 140/313 (44%), Gaps = 35/313 (11%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L L+K LD +A ++ + VL A P K+ + I++LD+NDN P F + Y+
Sbjct: 184 LILQKALDREA---MKEHKLVLT--AVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYS 238
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-----KGAFSIDPRSGWLTVRNQT 367
S+ EN P G V +V ATD D+G NG+ Y K FSIDP++G + V
Sbjct: 239 ASVNENSPPGTLVTRVNATDLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTG-- 296
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFAD-SQRIAKWRRQPLETNAPLEKTTYVFPDKVG 426
V+D E + S + V A + + T+ ++ P E + ++G
Sbjct: 297 VIDFEENESYEIDVQASDKGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIG 356
Query: 427 TKTENIEYYD-----------EQLMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKS- 471
T I D L S V V+V +LD NDN PV V SN ++
Sbjct: 357 TTVALISASDLDSVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEI 416
Query: 472 --NAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PI 527
N G ++ KV+A D D+G NG +L+ LQ S+ ++ F ++ TG + S
Sbjct: 417 PRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSL---FGLDRYTGQIRTLRSFTET 473
Query: 528 LEGRHALFVEASD 540
E H L + D
Sbjct: 474 DEAEHKLVILVKD 486
Score = 101 bits (242), Expect = 2e-19
Identities = 71/221 (32%), Positives = 110/221 (49%), Gaps = 22/221 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ EN PIGTT++++NA DLD GLNG++ Y F + V +++ F I+
Sbjct: 1400 VLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNV----------NHRLRKLFEIDADT 1449
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G +IV + E + ++I A D G+ L SV++ + D+ND+ P + T ++ V
Sbjct: 1450 GEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAV 1509
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL--TGVLSV--NGELDR 1110
E + + +D D G N + FI + D+PF +SP + SV LDR
Sbjct: 1510 PEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMYSVVTKSVLDR 1566
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E E KY +T+ A+D G DVNDNSP+F
Sbjct: 1567 EHESKYDITITAKDAG-DQPLSSHRTISVSVSDVNDNSPEF 1606
Score = 101 bits (242), Expect = 2e-19
Identities = 71/221 (32%), Positives = 110/221 (49%), Gaps = 22/221 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ EN PIGTT++++NA DLD GLNG++ Y F + V +++ F I+
Sbjct: 2154 VLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNV----------NHRLRKLFEIDADT 2203
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G +IV + E + ++I A D G+ L SV++ + D+ND+ P + T ++ V
Sbjct: 2204 GEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAV 2263
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL--TGVLSV--NGELDR 1110
E + + +D D G N + FI + D+PF +SP + SV LDR
Sbjct: 2264 PEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMYSVVTKSVLDR 2320
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E E KY +T+ A+D G DVNDNSP+F
Sbjct: 2321 EHESKYDITITAKDAG-DQPLSSHRTISVSVSDVNDNSPEF 2360
Score = 99.1 bits (236), Expect = 8e-19
Identities = 113/454 (24%), Positives = 184/454 (40%), Gaps = 26/454 (5%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+NV V +LD+NDN+P+F +Y + N GT + KVKA D D G NG + Y
Sbjct: 622 LNVTVIVLDSNDNHPIF-SQEVYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFFGGQ 680
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVT 560
+ F +N TG + V E L V A+D+ P ++ + ++
Sbjct: 681 QDRRTFDIFDLNKETGEIKVKGGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKVLD-- 738
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P I + S G S+ I DA V L +
Sbjct: 739 --QNDNAPQI-EVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKVMCSLSDNSPFDLKP 795
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKG 679
+ +E + + L R + YD A LS ++ V DVND K
Sbjct: 796 SFQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDFKTLSIDVSDVNDNAP---KY 852
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-----AE 734
+HSPI ++ EN+A + QIF S N ++ + I ++ A AE
Sbjct: 853 SHSPIELYLVENNAPGS--QIFSVTASDKDLNENADISYHIIREEGGQGKNAAFLNINAE 910
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+G I K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 911 NGQISALKSFDFETLKTFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSN 969
Query: 795 FIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFI 849
E +I + ++ ++A DAD G N ++ L +F +D TG ++ +
Sbjct: 970 GSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTL 1029
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
S + +KL ++ +D G +S A +++
Sbjct: 1030 -RSFTETDEAEHKLVILVKDNGNVSLSATATVLV 1062
Score = 96.7 bits (230), Expect = 4e-18
Identities = 134/499 (26%), Positives = 216/499 (43%), Gaps = 76/499 (15%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++ KPLD+E + + + A + G + +G + I + D NDN PVF +Y +
Sbjct: 1344 LYLHKPLDKETARSHTLVLTAA-DGGKPARSGTMTIKITVLDVNDNMPVFAKESYVAVLR 1402
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
ENS IGT + N ATD D+G N GE VV G++++
Sbjct: 1403 ENSPIGTTVLQVN---ATDLDDGLN--------GE------------VVYSFGNNVNHRL 1439
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
+ ++++ DTG + + + I E ++ E + I+ + K ET+ + T
Sbjct: 1440 RKLFEIDA---DTGEIIVKGQ----IDYEMKDRYEID-IKASDKGSAPLETEKS--VKIT 1489
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I+++ N A +++ +PE+ GTT+ ++ D DSG+NG++ N +V
Sbjct: 1490 ILDL---NDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDV--- 1543
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFV 1035
P LS L+ Y V+ + ++ R ES++ + I+A D G+ L+ + ++ V V
Sbjct: 1544 PFMLSP-TLQANMYSVVTKS----VLDRE--HESKYDITITAKDAGDQPLSSHRTISVSV 1596
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-----QPSDTD 1090
DVND+ P F Y F V E L V A D D N+ ++Y I Q
Sbjct: 1597 SDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAIT 1656
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
I+ G +S D E + + VVA D+G D NDN+P
Sbjct: 1657 SFLNINSENGQISALKSFDFEAQKMFQFQVVASDSG-SPSLSSNVTVKVFILDQNDNAPV 1715
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+P + SN + E + IP N G V KV A D D IG
Sbjct: 1716 IL---------YPVS---SNGSAEGLEEIP-------RNVNAGHLVTKVRAYDAD-IGY- 1754
Query: 1211 NGLILYSLPQRKNQQNLGL 1229
NG +L++L + + GL
Sbjct: 1755 NGWLLFALQEVSDHSLFGL 1773
Score = 96.7 bits (230), Expect = 4e-18
Identities = 134/499 (26%), Positives = 216/499 (43%), Gaps = 76/499 (15%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++ KPLD+E + + + A + G + +G + I + D NDN PVF +Y +
Sbjct: 2098 LYLHKPLDKETARSHTLVLTAA-DGGKPARSGTMTIKITVLDVNDNMPVFAKESYVAVLR 2156
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
ENS IGT + N ATD D+G N GE VV G++++
Sbjct: 2157 ENSPIGTTVLQVN---ATDLDDGLN--------GE------------VVYSFGNNVNHRL 2193
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
+ ++++ DTG + + + I E ++ E + I+ + K ET+ + T
Sbjct: 2194 RKLFEIDA---DTGEIIVKGQ----IDYEMKDRYEID-IKASDKGSAPLETEKS--VKIT 2243
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I+++ N A +++ +PE+ GTT+ ++ D DSG+NG++ N +V
Sbjct: 2244 ILDL---NDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDV--- 2297
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFV 1035
P LS L+ Y V+ + ++ R ES++ + I+A D G+ L+ + ++ V V
Sbjct: 2298 PFMLSP-TLQANMYSVVTKS----VLDRE--HESKYDITITAKDAGDQPLSSHRTISVSV 2350
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-----QPSDTD 1090
DVND+ P F Y F V E L V A D D N+ ++Y I Q
Sbjct: 2351 SDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAIT 2410
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
I+ G +S D E + + VVA D+G D NDN+P
Sbjct: 2411 SFLNINSENGQISALKSFDFEAQKMFQFQVVASDSG-SPSLSSNVTVKVFILDQNDNAPV 2469
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+P + SN + E + IP N G V KV A D D IG
Sbjct: 2470 IL---------YPVS---SNGSAEGLEEIP-------RNVNAGHLVTKVRAYDAD-IGY- 2508
Query: 1211 NGLILYSLPQRKNQQNLGL 1229
NG +L++L + + GL
Sbjct: 2509 NGWLLFALQEVSDHSLFGL 2527
Score = 91.9 bits (218), Expect = 1e-16
Identities = 110/517 (21%), Positives = 206/517 (39%), Gaps = 34/517 (6%)
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
++ G N + E + V V +LD ND++P F N + +A G
Sbjct: 1247 ERAGACVINTKIVLENPLEVHYVAVEVLDVNDHSPTF-SVNQTRLEISESALPGARFQLQ 1305
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEAS 539
A DPD + LY L + + + + + V P+ H L + A+
Sbjct: 1306 GAHDPDSDAYSIQLYKLSQNEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAA 1365
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
D ++ + ++V ++P F Y + N IGT+V Q+ D
Sbjct: 1366 DGGKPARSGTMTIKITVLDVN-------DNMPVFAKESYVAVLRENSPIGTTVLQVNATD 1418
Query: 600 AFE--QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NA 654
+ +V Y + + F ++ +G I V + + Y+ + A + +A
Sbjct: 1419 LDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSA 1478
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
L + + ++D+ND + + S + +++ G + I ++ S G
Sbjct: 1479 PLETEKSVKITILDLNDNAPEIEVTSFSKAV--PEDSKPGTTVALISVSDKDS--GVNGK 1534
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ F+ + + A ++ T+ LDRE Y +T+ A+ + G + ++
Sbjct: 1535 VICFINEDVPFMLSPTLQANMYSVVTKSVLDREHESKYDITITAK-DAGDQPLSSHRTIS 1593
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDN P F Y ++ EN+ GT + + A D DE N+L Y + G
Sbjct: 1594 VSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFS---VSAQDCDERDNSLISYNIIRNGN 1650
Query: 835 E------MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDE 886
+ +++ G + + S D E + M++ +VA D+G LSS + + I D+
Sbjct: 1651 QHQAITSFLNINSENGQISAL-KSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQ 1709
Query: 887 NDNKPE-FNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
NDN P + N E N AG + +V+
Sbjct: 1710 NDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 1746
Score = 91.9 bits (218), Expect = 1e-16
Identities = 110/517 (21%), Positives = 206/517 (39%), Gaps = 34/517 (6%)
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
++ G N + E + V V +LD ND++P F N + +A G
Sbjct: 2001 ERAGACVINTKIVLENPLEVHYVAVEVLDVNDHSPTF-SVNQTRLEISESALPGARFQLQ 2059
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEAS 539
A DPD + LY L + + + + + V P+ H L + A+
Sbjct: 2060 GAHDPDSDAYSIQLYKLSQNEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAA 2119
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
D ++ + ++V ++P F Y + N IGT+V Q+ D
Sbjct: 2120 DGGKPARSGTMTIKITVLDVN-------DNMPVFAKESYVAVLRENSPIGTTVLQVNATD 2172
Query: 600 AFE--QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NA 654
+ +V Y + + F ++ +G I V + + Y+ + A + +A
Sbjct: 2173 LDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSA 2232
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
L + + ++D+ND + + S + +++ G + I ++ S G
Sbjct: 2233 PLETEKSVKITILDLNDNAPEIEVTSFSKAV--PEDSKPGTTVALISVSDKDS--GVNGK 2288
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ F+ + + A ++ T+ LDRE Y +T+ A+ + G + ++
Sbjct: 2289 VICFINEDVPFMLSPTLQANMYSVVTKSVLDREHESKYDITITAK-DAGDQPLSSHRTIS 2347
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDN P F Y ++ EN+ GT + + A D DE N+L Y + G
Sbjct: 2348 VSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFS---VSAQDCDERDNSLISYNIIRNGN 2404
Query: 835 E------MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDE 886
+ +++ G + + S D E + M++ +VA D+G LSS + + I D+
Sbjct: 2405 QHQAITSFLNINSENGQISAL-KSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQ 2463
Query: 887 NDNKPE-FNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
NDN P + N E N AG + +V+
Sbjct: 2464 NDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 2500
Score = 90.2 bits (214), Expect = 4e-16
Identities = 136/531 (25%), Positives = 225/531 (42%), Gaps = 57/531 (10%)
Query: 607 SYDLLHG--YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNAT 663
SY L H ++ + + E++ + + L R + + AL N + S N T
Sbjct: 2738 SYKLSHNDCFDIDIRESEEDKIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLT 2797
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ V+D ND R V K + + + EN+ G + Q+ T++ NG F
Sbjct: 2798 IEVLDTNDNRPVFSKDIY---LVSLDENAQRGTLVVQLNATDLDEGL-NGEIEYSFGKTQ 2853
Query: 723 QQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
++ V D + + G I + +D E+ +V+R+ + A +KG + +V I I+D N
Sbjct: 2854 KKKVQDTFELDSVTGEIRVKGNVDFEETEVFRLDIQAS-DKGHLPWTAESRVVIKIKDIN 2912
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD--- 838
DN P E + + E++K GT I ++I D D G N + + G+ FD
Sbjct: 2913 DNRPEIEITSLSTSVPEDAKPGTVI---SLISIRDKDSGLNGKVICKISGD--VPFDLTP 2967
Query: 839 -VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
++EN + G LDRE+ Y + + A D G LS+ L + + D NDN+P FNQ
Sbjct: 2968 SIEENMYSLVTKG-RLDRERVAHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQ 3026
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
+ ++ N G +I V A+D D L L+ NI G ++
Sbjct: 3027 ----NPFELYLVE--NNAPGASIFSVS-----AVD-DDLNENALVNYNIIRGDGLLN--- 3071
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRL 1015
DL + LN I E N ++ S + L+ ++ V+ G + SL S +
Sbjct: 3072 -DLTAFLN--INSE-NGQISALKS-FDFETLKTFQFQVVASDSG----SPSL--SSNVTV 3120
Query: 1016 NISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
+ LD NDN V ++ N ++ N N ++ KV A DAD G
Sbjct: 3121 KVFILD---QNDNAPVILYPVSSNGSAEGLEEIPRNVN------AGHLVTKVRAYDADIG 3171
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
N L + +Q F + TG + E ++ L ++ +DNG
Sbjct: 3172 YNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDETEHKLVILVKDNG 3222
Score = 88.6 bits (210), Expect = 1e-15
Identities = 166/697 (23%), Positives = 276/697 (39%), Gaps = 85/697 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V + D NDN P F+ + + +K N+ VG + + AVD D+ Q+G V Y
Sbjct: 3580 LSSTSTVAVQVSDVNDNAPRFLEQAINIY-VKENSPVGATMKTITAVDADVDQSGQVRYS 3638
Query: 499 -LQRTS-NLTITSPFKINPNTGT-VSVAESPILEGRHALF-VEASDQPANPSERRYSLAV 554
LQR S + ++S IN TG VS+ E + F V+A+D P S+ V
Sbjct: 3639 YLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVSVNV 3698
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
++ N P I APY N + V + + D+ +
Sbjct: 3699 FILD----ENDNNPAIL----APYSEHGSVNTTVSIEVVVV---------ESGADIQTPF 3741
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
VP V+E S DL+ Y +A+ + + +++ T+ V + G
Sbjct: 3742 RHNVP--VKEES-----FSDLNLYL-------LIAIVAVSAIFLLSLITLIAVRCHRTDG 3787
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-A 733
L G+ S + EN+ + + N Q DV D I
Sbjct: 3788 GL--GSRSLYKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDP 3845
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G I +D E+ + + A +KG + +V + + D NDN P +
Sbjct: 3846 KSGAILVNGKIDYEENPAFEIHAQAS-DKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLL 3904
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
+ E++++GT I + +++ D D G N + + D + + +L
Sbjct: 3905 STVKEDAEVGTAIALVSVL---DKDGGKNGIVRAAIANHVPFKLDTNYKNYYSLVVNGAL 3961
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
DRE + + +++VA D G LSS + + + + D NDN P F +E+ + + K N
Sbjct: 3962 DRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRF--LEQAINIYV----KEN 4015
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
G T +K DVDQ G + + ++ N+ L+ I N
Sbjct: 4016 SPVGAT---MKTITAVDADVDQSG---------QVRYSYLQSNS--ESQPLSSMI--NIN 4059
Query: 972 SEVYIPPSKLSADALEVKRY-FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNIS 1030
SE S S D E+K + F + V P S +N+ LD NDN
Sbjct: 4060 SETGDIVSLQSFDYEELKTFQFQVQATDSGV-----PPLSSNVSVNVFILDE---NDNNP 4111
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDT 1089
+ ++H V ++ ++ E + + K+ A D D G NA L+Y + +P
Sbjct: 4112 --AILAPYSEHGSVNSES-IPYSAEAGYF----VAKIRAVDLDSGYNALLSYHLSEPKGN 4164
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+L F + TG + + + L V+ DNG
Sbjct: 4165 NL-FRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNG 4200
Score = 86.6 bits (205), Expect = 5e-15
Identities = 85/335 (25%), Positives = 144/335 (42%), Gaps = 25/335 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHGYEEGVP--FAVEERS 626
P F + Y+ + N+ GT+V + D ++ ++ + L + V F ++ +S
Sbjct: 3385 PVFSRSLYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKS 3444
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPII 685
G I V + P ++ A A + +S V V+DVND + +P++
Sbjct: 3445 GAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITV---TPLL 3501
Query: 686 FHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPL 744
VKE++ G AI + + G G VR IAN D ++ L
Sbjct: 3502 STVKEDAEVGTAIALVSVLDKD---GGKNGIVRAAIANHVPFKLDTNYKNYYSLVVNGAL 3558
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
DRE + + +T++A ++G + V + + D NDN P F ++ ENS +G
Sbjct: 3559 DRESQAQFNVTIVA-CDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGA 3617
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKE------MFDVDENTGVVKFIGDSLDREKK 858
+K I A DAD + Y+ E M +++ TG + + S D E+
Sbjct: 3618 TMKT---ITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSL-QSFDYEEL 3673
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
++ + A D+G LSS + + I DENDN P
Sbjct: 3674 KTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNP 3708
Score = 85.0 bits (201), Expect = 1e-14
Identities = 59/179 (32%), Positives = 91/179 (50%), Gaps = 14/179 (7%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
++ LDREK + + ++ + G +G VT+ + D NDN P+F Y + EN
Sbjct: 593 ERLLDREKLREHHL-ILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENV 651
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK----EMFDVDENTGVVKFIGDSLDRE 856
GT + +KATD DEG N Y G+ ++FD+++ TG +K G +D E
Sbjct: 652 AAGTSVIK---VKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKG-GIDFE 707
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
K ++KL + A D G +S++ +II + D+NDN P QIE S + E GT
Sbjct: 708 KVEVFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAP---QIEVTSLSNVVPEDSKPGT 763
Score = 84.2 bits (199), Expect = 2e-14
Identities = 95/381 (24%), Positives = 163/381 (42%), Gaps = 28/381 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+++LD NDN PVF S LY+ + N + GT + + A D D N + + L+
Sbjct: 3375 ISVLDINDNAPVFSRS-LYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLRSKGQND 3433
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ F+I+P +G + V E A + +ASD+ P + V ++V
Sbjct: 3434 VLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDV----- 3488
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE- 623
+ P+ P V + +GT++ + V D + + + VPF ++
Sbjct: 3489 --NDNAPEITVTPLLSTVKEDAEVGTAIALVSVLD--KDGGKNGIVRAAIANHVPFKLDT 3544
Query: 624 --ERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGA 680
+ + V L R ++ ++ VA E A LS + V V DVND L+ A
Sbjct: 3545 NYKNYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQA 3604
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIAI-AEDGT 737
I +VKENS A + + + +G +L N Q ++ I I +E G
Sbjct: 3605 ---INIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGD 3661
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I + + D E+ ++ V A + GV + V ++I DENDN P A Y
Sbjct: 3662 IVSLQSFDYEELKTFQFQVQAT-DSGVPPLSSNVSVNVFILDENDNNPAI-LAPYS---- 3715
Query: 798 ENSKIGTEIKMDNIIKATDAD 818
E+ + T + ++ ++ + AD
Sbjct: 3716 EHGSVNTTVSIEVVVVESGAD 3736
Score = 82.2 bits (194), Expect = 1e-13
Identities = 92/337 (27%), Positives = 146/337 (43%), Gaps = 57/337 (16%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ QK LDRE +++ V+ + G + +G + I + D NDN PVF Y +
Sbjct: 184 LILQKALDREAMKEHKL-VLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVN 242
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDENTGVVKFIGDS 852
ENS GT + + ATD DEG N +Y+ FG+ K F +D TG +K G
Sbjct: 243 ENSPPGTLVTR---VNATDLDEGANGDIIYS-FGQEVDTRVKNKFSIDPKTGDIKVTG-V 297
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF------NQIEENSKV-- 902
+D E+ Y++ + A D G LS+ +II + D NDN PE + E+S++
Sbjct: 298 IDFEENESYEIDVQASDKGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGT 357
Query: 903 ------RIHRETKLNGTAGFTIIEVKPKNK-FALDVDQLGPLFL--------------IP 941
++ + +G + K F LD + P+ L IP
Sbjct: 358 TVALISASDLDSVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIP 417
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
N+ G + K+ A D D G NG + + ++S +L F ++ G +
Sbjct: 418 RNVNAGHLVTKVRAYDADIGYNGWLLFAL--------QEVSDHSL-----FGLDRYTGQI 464
Query: 1002 IVARSL--PPESEFRLNISALDGGNLNDNISVRVFVK 1036
RS E+E +L I D GN++ + + V VK
Sbjct: 465 RTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVK 501
Score = 79.8 bits (188), Expect = 5e-13
Identities = 122/503 (24%), Positives = 205/503 (40%), Gaps = 77/503 (15%)
Query: 897 EENSKVRIHRETKLNGTAGFT-----IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
EEN IH + G + ++EV N A ++ L + E+ +GT I
Sbjct: 3456 EENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKEDAEVGTAIA 3515
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
++ LD D G NG +R + V P KL + K Y+ + +V +L ES
Sbjct: 3516 LVSVLDKDGGKNGIVRAAIANHV---PFKLDTN---YKNYYSL-------VVNGALDRES 3562
Query: 1012 EFRLNIS--ALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ + N++ A D G L+ +V V V DVND+ P F + N V+E + +
Sbjct: 3563 QAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGATMKTI 3622
Query: 1068 DATDADFGQNANLTY-FIQPSDTDLP----FEISPLTGVLSVNGELDRETEDKYILTVVA 1122
A DAD Q+ + Y ++Q + P I+ TG + D E + V A
Sbjct: 3623 TAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQA 3682
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
D+G D NDN+P A P ++ S + S+ ++
Sbjct: 3683 TDSG-VPPLSSNVSVNVFILDENDNNPAILA---------PYSEHGSVNTTVSIEVV--- 3729
Query: 1183 KATIEENAPIGTTVA-KVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL-MV 1240
+E A I T V + F + L LY L + + ++S+ +L ++
Sbjct: 3730 --VVESGADIQTPFRHNVPVKEESF----SDLNLYLL--------IAIVAVSAIFLLSLI 3775
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNEN 1298
T+ V +D + Y+ +I EN A ++ LN T+ + N ++ + + ++
Sbjct: 3776 TLIAV--RCHRTDGGLGSRSLYKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLRSKG 3833
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEG 1358
D+ F IDP++G + + D E +E I+ A D +
Sbjct: 3834 QNDVLDLFRIDPKSGAILVNGKIDYEENPAFE-----------------IHAQASDKGQP 3876
Query: 1359 MTKYDVKVVVRIKDVNDNSPKFT 1381
D KV+V + DVNDN+P+ T
Sbjct: 3877 PMSTDCKVLVEVLDVNDNAPEIT 3899
Score = 79.8 bits (188), Expect = 5e-13
Identities = 103/434 (23%), Positives = 178/434 (41%), Gaps = 27/434 (6%)
Query: 463 NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV 522
+LY+ + N + GT + + A D D N + + L+ + F+I+P +G + V
Sbjct: 3793 SLYKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAILV 3852
Query: 523 AESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
E A + +ASD+ P + V ++V + P+
Sbjct: 3853 NGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDV-------NDNAPEITVTSLLS 3905
Query: 581 WVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE---ERSGVITVVDDLSR 637
V + +GT++ + V D + + + VPF ++ + + V L R
Sbjct: 3906 TVKEDAEVGTAIALVSVLD--KDGGKNGIVRAAIANHVPFKLDTNYKNYYSLVVNGALDR 3963
Query: 638 YNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
++ ++ VA E A LS + V V DVND L+ A I +VKENS A
Sbjct: 3964 ESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQA---INIYVKENSPVGA 4020
Query: 697 IGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIAI-AEDGTIFTQKPLDREKRDVYR 753
+ + + +G +L +N Q ++ I I +E G I + + D E+ ++
Sbjct: 4021 TMKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEELKTFQ 4080
Query: 754 MTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI-- 811
V A + GV + V ++I DENDN P E + + I +
Sbjct: 4081 FQVQAT-DSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVA 4139
Query: 812 -IKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
I+A D D G NAL Y L +G +F + +TG ++ D + K + L ++ D
Sbjct: 4140 KIRAVDLDSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLK-SHPLVVLVSD 4198
Query: 870 TGGLSSEAELIIMI 883
G S A + I +
Sbjct: 4199 NGEPSLSATVSIEV 4212
Score = 78.2 bits (184), Expect = 2e-12
Identities = 65/220 (29%), Positives = 101/220 (45%), Gaps = 22/220 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN+ GT++IK+ A DLD G NG+I Y F + + + D F +N+ G
Sbjct: 647 VPENVAAGTSVIKVKATDLDEGANGEIEYFFGGQ----QDRRTFD------IFDLNKETG 696
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V + E F+L++ A D G ++ + +V + V D ND+ P + T + V
Sbjct: 697 EIKVKGGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVP 756
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL----TGVLSVNGELDRE 1111
E V+ + TD D G N + + SD PF++ P L + LDRE
Sbjct: 757 EDSKPGTVISLISITDLDAGLNGKVMCSL--SDNS-PFDLKPSFQENMYSLVLKQPLDRE 813
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ Y +T+ A D G DVNDN+PK+
Sbjct: 814 SVSHYDVTITATDCG-QPALSDFKTLSIDVSDVNDNAPKY 852
Score = 78.2 bits (184), Expect = 2e-12
Identities = 68/219 (31%), Positives = 99/219 (45%), Gaps = 21/219 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN GTT+I LNA D D LN +I + SK D L++ F I+ + G
Sbjct: 3799 IPENTQAGTTVIVLNATDEDKELNAEIEFSLR-------SKGQNDVLDL---FRIDPKSG 3848
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++V + E F ++ A D G ++ + V V V DVND+ P T V+
Sbjct: 3849 AILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLLSTVK 3908
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRET 1112
E + V D D G+N + I +PF++ L VNG LDRE+
Sbjct: 3909 EDAEVGTAIALVSVLDKDGGKNGIVRAAIA---NHVPFKLDTNYKNYYSLVVNGALDRES 3965
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ ++ +T+VA D G DVNDN+P+F
Sbjct: 3966 QAQFNVTIVACDEG-APPLSSTSTVAVQVSDVNDNAPRF 4003
Score = 74.9 bits (176), Expect = 2e-11
Identities = 52/157 (33%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 1001 VIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+I+ ++L E+ E +L ++A+DGG + + + + V DVND+ PVF K Y+ +V E
Sbjct: 184 LILQKALDREAMKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNE 243
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL--PFEISPLTGVLSVNGELDRETE 1113
++ +V+ATD D G N ++ Y F Q DT + F I P TG + V G +D E
Sbjct: 244 NSPPGTLVTRVNATDLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEEN 303
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ Y + V A D G D+NDN P+
Sbjct: 304 ESYEIDVQASDKG-TIPLSTYRSVIIKVKDLNDNPPE 339
Score = 74.1 bits (174), Expect = 3e-11
Identities = 107/418 (25%), Positives = 172/418 (41%), Gaps = 52/418 (12%)
Query: 1012 EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
E L ++A+DGGN + ++V V V D ND+ P+F + Y+ +V E + KV A
Sbjct: 603 EHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKA 662
Query: 1070 TDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
TD D G N + YF Q T F+++ TG + V G +D E + + L V A D G
Sbjct: 663 TDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFEKVEVFKLDVHATDKG 722
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATI 1186
D NDN+P+ E+ + ++ S++ I A +
Sbjct: 723 -QPPMSTDCTVIIKVLDQNDNAPQI----EVTSLSNVVPEDSKPGTVISLISITDLDAGL 777
Query: 1187 EENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN---------QQNLGLPSLSSTAI 1237
+ F F N L+L R++ + G P+LS
Sbjct: 778 NGKVMCSLSDNSPFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDFKT 837
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP-VELVSLNLTEH--YENFKMRYYI 1294
L + V+DV D + P + EL + EN NAP ++ S+ ++ EN + Y+I
Sbjct: 838 LSIDVSDVND-----NAPKYSHSPIELYLVEN-NAPGSQIFSVTASDKDLNENADISYHI 891
Query: 1295 LNENDTDIRR-TFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
+ E + F+ I+ NG + ++S D E T++ V VA
Sbjct: 892 IREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQV-----------------VA 934
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKF-----TNGNRPLVTAIPTTAPFGYQVMQLK 1405
D +V V V I D NDN+P +NG+ + IP G+ V +++
Sbjct: 935 SDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 992
Score = 73.7 bits (173), Expect = 3e-11
Identities = 87/382 (22%), Positives = 163/382 (42%), Gaps = 25/382 (6%)
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
T+ VT + + P F Y V NV GTSV +++ D E + + G +
Sbjct: 621 TLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFFGGQ 680
Query: 616 EGVP----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVN 670
+ F + + +G I V + ++ + A + +S + V+D N
Sbjct: 681 QDRRTFDIFDLNKETGEIKVKGGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKVLDQN 740
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + S ++ +++ G I I T++ + G V +++
Sbjct: 741 DNAPQIEVTSLSNVV--PEDSKPGTVISLISITDLDA---GLNGKVMCSLSDNSPFDLKP 795
Query: 731 AIAEDG-TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ E+ ++ ++PLDRE Y +T+ A + G + + ++I + D NDN P + H
Sbjct: 796 SFQENMYSLVLKQPLDRESVSHYDVTITAT-DCGQPALSDFKTLSIDVSDVNDNAPKYSH 854
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKE--MFDVDENT 843
+ E +++EN+ G++I + A+D D NA Y + G+GK +++
Sbjct: 855 SPIELYLVENNAPGSQIFS---VTASDKDLNENADISYHIIREEGGQGKNAAFLNINAEN 911
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE-FNQIEENS 900
G + + S D E ++ +VA D+G LSS + + I D+NDN P + N
Sbjct: 912 GQISAL-KSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNG 970
Query: 901 KVRIHRETKLNGTAGFTIIEVK 922
E N AG + +V+
Sbjct: 971 SAEGLEEIPRNVNAGHLVTKVR 992
Score = 72.9 bits (171), Expect = 6e-11
Identities = 72/273 (26%), Positives = 120/273 (43%), Gaps = 23/273 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA-PIGPSLTIPLTVPRGLTIF 141
V V I DVND+ P F ++ + + E TP G + I P +LT+ F
Sbjct: 2688 VGVEIADVNDHAPSFPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCF 2747
Query: 142 K-DIRAFDRDK--------PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
DIR + DK P +S+ DG S + + +VLD +
Sbjct: 2748 DIDIRESEEDKIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTI--EVLDTND 2805
Query: 193 GDKEFQ--LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL---FSLD 247
F + +++ + + L + ++A D D G+ + Y +K+ F LD
Sbjct: 2806 NRPVFSKDIYLVSLDENAQRGTLVVQ-LNATDLDEGLNGEIEYSFGKTQKKKVQDTFELD 2864
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
SV G + ++ +D + + F L +QAS + TA++RV I++ D+NDN PE E
Sbjct: 2865 SVTGEIRVKGNVDFE-----ETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIE 2919
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ + S+ E+ G + + DKD G NG+
Sbjct: 2920 ITSLSTSVPEDAKPGTVISLISIRDKDSGLNGK 2952
Score = 72.1 bits (169), Expect = 1e-10
Identities = 105/427 (24%), Positives = 168/427 (39%), Gaps = 42/427 (9%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
EDG ++ K LDRE + + + I+ V I + D ND+ P F
Sbjct: 70 EDGILYVSKKLDREVICEKSNVCVINLKTVLENPLEIHYVAIEVLDVNDHSPTFPENEKR 129
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK----FI 849
I E++ G ++ A D D G + Y L +V E K +
Sbjct: 130 LEIFESTSTGARFQLQ---PARDPDGGQFTVQQYRLSPNDHFRLEVKERGEDRKMPFLIL 186
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ------IEENSK 901
+LDRE +KL L A D G S +II + D NDN P F + + ENS
Sbjct: 187 QKALDREAMKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSP 246
Query: 902 -----VRIHRETKLNGTAGFTI------IEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
R++ G G I ++ + KNKF++D + G I I
Sbjct: 247 PGTLVTRVNATDLDEGANGDIIYSFGQEVDTRVKNKFSID-PKTGD---IKVTGVIDFEE 302
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD--ALEVKRYFVINERHGHVIVARSLP 1008
+ +D+ + G I V I L+ + +E+ + + +L
Sbjct: 303 NESYEIDVQASDKGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALI 362
Query: 1009 PESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPV-FKKTWYNFNVEEAQYTRR--- 1062
S+ ++ A D G +L+ N++V+VF+ D ND+ PV N + E + R
Sbjct: 363 SASDLD-SVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVN 421
Query: 1063 ---VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++ KV A DAD G N L + +Q F + TG + E ++ L
Sbjct: 422 AGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLV 481
Query: 1120 VVARDNG 1126
++ +DNG
Sbjct: 482 ILVKDNG 488
Score = 67.3 bits (157), Expect = 3e-09
Identities = 67/233 (28%), Positives = 108/233 (46%), Gaps = 28/233 (12%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L+L K LD + A + L + A+ P ++ ++I +LD+NDN+P F + Y
Sbjct: 1344 LYLHKPLDKET-----ARSHTLVLTAADGGKPARSGTMTIKITVLDVNDNMPVFAKESYV 1398
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-----KGAFSIDPRSGWLTVRNQT 367
+ EN P G +VLQV ATD D G NGE Y + + F ID +G + V+ Q
Sbjct: 1399 AVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQI 1458
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTTY--VFPD- 423
+ + + +K K + P ++++ K L NAP +E T++ P+
Sbjct: 1459 DYEMKDRYEIDIKASDKGSAP------LETEKSVKITILDLNDNAPEIEVTSFSKAVPED 1512
Query: 424 -KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF----VPSNLYEFSMKS 471
K GT I D+ S VN +V + N++ P + +N+Y KS
Sbjct: 1513 SKPGTTVALISVSDKD--SGVNGKV-ICFINEDVPFMLSPTLQANMYSVVTKS 1562
Score = 67.3 bits (157), Expect = 3e-09
Identities = 67/233 (28%), Positives = 108/233 (46%), Gaps = 28/233 (12%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L+L K LD + A + L + A+ P ++ ++I +LD+NDN+P F + Y
Sbjct: 2098 LYLHKPLDKET-----ARSHTLVLTAADGGKPARSGTMTIKITVLDVNDNMPVFAKESYV 2152
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-----KGAFSIDPRSGWLTVRNQT 367
+ EN P G +VLQV ATD D G NGE Y + + F ID +G + V+ Q
Sbjct: 2153 AVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQI 2212
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTTY--VFPD- 423
+ + + +K K + P ++++ K L NAP +E T++ P+
Sbjct: 2213 DYEMKDRYEIDIKASDKGSAP------LETEKSVKITILDLNDNAPEIEVTSFSKAVPED 2266
Query: 424 -KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF----VPSNLYEFSMKS 471
K GT I D+ S VN +V + N++ P + +N+Y KS
Sbjct: 2267 SKPGTTVALISVSDKD--SGVNGKV-ICFINEDVPFMLSPTLQANMYSVVTKS 2316
Score = 66.9 bits (156), Expect = 4e-09
Identities = 56/177 (31%), Positives = 81/177 (45%), Gaps = 16/177 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLD---SVNGSL-FLEKELDLDAEHNLQANTFV 273
IHA T+R +S ND F +D S + FL + LD E Q +
Sbjct: 2723 IHAARDPDAATLTVRSYKLSHND--CFDIDIRESEEDKIPFLVLKKPLDREQKAQHS--- 2777
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L + A NP ++ + IE+LD NDN P F D Y +S+ EN G V+Q+ ATD
Sbjct: 2778 LTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLVSLDENAQRGTLVVQLNATDL 2837
Query: 334 DQGENGEFTY-----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+G NGE Y Q + F +D +G + V+ +D E R+ + A +
Sbjct: 2838 DEGLNGEIEYSFGKTQKKKVQDTFELDSVTGEIRVKGN--VDFEETEVFRLDIQASD 2892
Score = 66.9 bits (156), Expect = 4e-09
Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 6/146 (4%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+++ L ++ALDGGN + ++++ + V D ND+ PVF K Y +++E ++ ++
Sbjct: 2773 KAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLVSLDENAQRGTLVVQL 2832
Query: 1068 DATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+ATD D G N + Y Q FE+ +TG + V G +D E + + L + A D
Sbjct: 2833 NATDLDEGLNGEIEYSFGKTQKKKVQDTFELDSVTGEIRVKGNVDFEETEVFRLDIQASD 2892
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPK 1150
G D+NDN P+
Sbjct: 2893 KG-HLPWTAESRVVIKIKDINDNRPE 2917
Score = 66.9 bits (156), Expect = 4e-09
Identities = 44/152 (28%), Positives = 74/152 (48%), Gaps = 12/152 (7%)
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D + L L+K+LD + + + L + A NP K+ +++ I +LD+NDN P F
Sbjct: 3333 DRTSAHLVLQKQLDREKQ-----DVISLTLTALDGGNPPKSGTSQIIISVLDINDNAPVF 3387
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWL 361
Y I EN+ G +V+ + ATD+D+ N E + L +D F IDP+SG +
Sbjct: 3388 SRSLYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAI 3447
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
V + +D E + + + A + + T
Sbjct: 3448 LVNGK--IDYEENPAFEIHAQASDKGQPPMST 3477
Score = 63.7 bits (148), Expect = 4e-08
Identities = 44/159 (27%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + + +LD NDN+PVF +Y S+ N+ GT++ +V A D D G NG ++Y +
Sbjct: 216 MGIIIQVLDVNDNSPVFT-KEVYSASVNENSPPGTLVTRVNATDLDEGANGDIIYSFGQE 274
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ + + F I+P TG + V E + + V+ASD+ P Y ++ +
Sbjct: 275 VDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASDKGTIPLS-TYRSVIIKV--- 330
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
+ N P+I + V + IGT+V I +D
Sbjct: 331 KDLNDNPPEIEI---TSFSKSVPEDSRIGTTVALISASD 366
Score = 60.5 bits (140), Expect = 3e-07
Identities = 62/240 (25%), Positives = 102/240 (42%), Gaps = 15/240 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D+ L S + V++ D NDN+P FV +N Y F + N GT + V A D D N ++
Sbjct: 1583 DQPLSSHRTISVSVSDVNDNSPEFV-TNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLI 1641
Query: 496 LYDLQRTSN--LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYS 551
Y++ R N ITS IN G +S +S E + V ASD + +
Sbjct: 1642 SYNIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVT 1701
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-- 609
+ V ++ + A + NV G V ++R DA D+ Y+
Sbjct: 1702 VKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDA----DIGYNGW 1757
Query: 610 LLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
LL +E F ++ +G I + + + + + +++N N+S+ ATV V
Sbjct: 1758 LLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VILVKDNGNVSLSATATVLV 1816
Score = 60.5 bits (140), Expect = 3e-07
Identities = 62/240 (25%), Positives = 102/240 (42%), Gaps = 15/240 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D+ L S + V++ D NDN+P FV +N Y F + N GT + V A D D N ++
Sbjct: 2337 DQPLSSHRTISVSVSDVNDNSPEFV-TNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLI 2395
Query: 496 LYDLQRTSN--LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYS 551
Y++ R N ITS IN G +S +S E + V ASD + +
Sbjct: 2396 SYNIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVT 2455
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-- 609
+ V ++ + A + NV G V ++R DA D+ Y+
Sbjct: 2456 VKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDA----DIGYNGW 2511
Query: 610 LLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
LL +E F ++ +G I + + + + + +++N N+S+ ATV V
Sbjct: 2512 LLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VILVKDNGNVSLSATATVLV 2570
Score = 58.8 bits (136), Expect = 1e-06
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 19/200 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN GTT+ ++A D D N I Y + + + IN
Sbjct: 1613 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNI--------IRNGNQHQAITSFLNINSE 1664
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNF 1052
+G + +S E++ F+ + A D G+ L+ N++V+VF+ D ND+ PV N
Sbjct: 1665 NGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNG 1724
Query: 1053 NVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 1725 SAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLR 1784
Query: 1107 ELDRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 1785 SFTETDEAEHKLVILVKDNG 1804
Score = 58.8 bits (136), Expect = 1e-06
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 19/200 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN GTT+ ++A D D N I Y + + + IN
Sbjct: 2367 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNI--------IRNGNQHQAITSFLNINSE 2418
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNF 1052
+G + +S E++ F+ + A D G+ L+ N++V+VF+ D ND+ PV N
Sbjct: 2419 NGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNG 2478
Query: 1053 NVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 2479 SAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLR 2538
Query: 1107 ELDRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 2539 SFTETDEAEHKLVILVKDNG 2558
Score = 57.2 bits (132), Expect = 3e-06
Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 23/202 (11%)
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NP ++ V + +LD NDN P F + Y+ + EN+ G SV++V ATD D+G NGE
Sbjct: 615 NPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKATDLDEGANGEIE 674
Query: 343 YQLDDPK-----GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS 397
Y + F ++ +G + V+ +D E ++ V+A + + T D
Sbjct: 675 YFFGGQQDRRTFDIFDLNKETGEIKVKGG--IDFEKVEVFKLDVHATDKGQPPMST--DC 730
Query: 398 QRIAKWRRQPLETNAP-LEKTTY--VFPD--KVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
I K Q NAP +E T+ V P+ K GT I D L + +N +V +
Sbjct: 731 TVIIKVLDQ--NDNAPQIEVTSLSNVVPEDSKPGTVISLISITD--LDAGLNGKV-MCSL 785
Query: 453 NDNNPV-FVPS---NLYEFSMK 470
+DN+P PS N+Y +K
Sbjct: 786 SDNSPFDLKPSFQENMYSLVLK 807
Score = 56.8 bits (131), Expect = 4e-06
Identities = 53/175 (30%), Positives = 78/175 (44%), Gaps = 26/175 (14%)
Query: 218 IHAIDQDLGVGATLRYELISG----NDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A+D DL A + Y +I G ND F +++S NG + K D + TF
Sbjct: 3046 VSAVDDDLNENALVNYNIIRGDGLLNDLTAFLNINSENGQISALKSFDFET-----LKTF 3100
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS----------IVENLPNG 322
QV AS +P ++ V++ +LD NDN P V Y +S I N+ G
Sbjct: 3101 QFQVVASDSGSPSLSSNVTVKVFILDQNDNAP---VILYPVSSNGSAEGLEEIPRNVNAG 3157
Query: 323 FSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVLDREAH 374
V +V A D D G NG + L + F +D +G + T+R+ T D H
Sbjct: 3158 HLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDETEH 3212
Score = 56.4 bits (130), Expect = 6e-06
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 11/182 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G + Y DR+ F + +N G + ++ +D + + F L
Sbjct: 660 VKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFE-----KVEVFKL 714
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A+ P + V I++LD NDN P+ EV + + E+ G + + TD D
Sbjct: 715 DVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLD 774
Query: 335 QGENGEFTYQLDDPKGAFSIDP--RSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
G NG+ L D F + P + ++ + LDRE+ S + + A + +
Sbjct: 775 AGLNGKVMCSLSD-NSPFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALS 833
Query: 393 TF 394
F
Sbjct: 834 DF 835
Score = 55.6 bits (128), Expect = 1e-05
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 12/158 (7%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+ V+DVND V K +S V ENS + + N + + G++ + +
Sbjct: 220 IQVLDVNDNSPVFTKEVYSA---SVNENSPPGTL--VTRVNATDLDEGANGDIIYSFGQE 274
Query: 724 QD--VTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
D V + +I + G I +D E+ + Y + V A +KG I + V I ++D
Sbjct: 275 VDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQAS-DKGTIPLSTYRSVIIKVKDL 333
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
NDNPP E ++ + E+S+IGT + +I A+D D
Sbjct: 334 NDNPPEIEITSFSKSVPEDSRIGTTVA---LISASDLD 368
Score = 55.6 bits (128), Expect = 1e-05
Identities = 55/201 (27%), Positives = 87/201 (43%), Gaps = 20/201 (9%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L+L+ N P G+ I + A D D N I Y E K +A + IN
Sbjct: 859 LYLVENNAP-GSQIFSVTASDKDLNENADISYHIIREEG-GQGKNAA-------FLNINA 909
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYN 1051
+G + +S E+ F+ + A D G+ L+ N++V+VF+ D ND+ PV N
Sbjct: 910 ENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSN 969
Query: 1052 FNVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 970 GSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTL 1029
Query: 1106 GELDRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 1030 RSFTETDEAEHKLVILVKDNG 1050
Score = 55.6 bits (128), Expect = 1e-05
Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 12/169 (7%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++G ++ K +DRE+ + V S I+ V + I D ND+ P F +
Sbjct: 2649 DNGVLYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGVEIADVNDHAPSFPESEQR 2708
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD-----ENTGVVKF 848
I E++ GT + I A D D T + Y L + FD+D E+
Sbjct: 2709 LEIAEHTPPGTRFQ---IHAARDPDAATLTVRSYKL--SHNDCFDIDIRESEEDKIPFLV 2763
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ LDRE+K + L+L A D G S L I + D NDN+P F++
Sbjct: 2764 LKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSK 2812
Score = 54.8 bits (126), Expect = 2e-05
Identities = 61/240 (25%), Positives = 100/240 (41%), Gaps = 15/240 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L + ++ V + D NDN PVF N +E + N G I V AVD DL +N +V
Sbjct: 3001 DPPLSAVKSLTVYVSDVNDNRPVF-NQNPFELYLVENNAPGASIFSVSAVDDDLNENALV 3059
Query: 496 LYDLQRTSNL--TITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYS 551
Y++ R L +T+ IN G +S +S E V ASD + +
Sbjct: 3060 NYNIIRGDGLLNDLTAFLNINSENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVT 3119
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-- 609
+ V ++ + A + NV G V ++R DA D+ Y+
Sbjct: 3120 VKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDA----DIGYNGW 3175
Query: 610 LLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
LL +E F ++ +G I + + + + + +++N N+S+ ATV V
Sbjct: 3176 LLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDETEHKL-VILVKDNGNVSLSATATVLV 3234
Score = 54.4 bits (125), Expect = 2e-05
Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 12/213 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D D+ +RY + N +N + + L + + TF QVQ
Sbjct: 4025 ITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQ 4084
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLPN----GFSVLQVMAT 331
A+ P ++ V + +LD NDN P + V E++P G+ V ++ A
Sbjct: 4085 ATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAV 4144
Query: 332 DKDQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D D G N +Y L +PKG F + +G + + + + D + S + + + PS
Sbjct: 4145 DLDSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRR-MSDNDLKSHPLVVLVSDNGEPS 4203
Query: 390 VVGTFADSQRIAKWR---RQPLETNAPLEKTTY 419
+ T + + + + P N P+++ ++
Sbjct: 4204 LSATVSIEVVVVESGADIQTPFRHNVPMKEESF 4236
Score = 53.2 bits (122), Expect = 5e-05
Identities = 67/292 (22%), Positives = 120/292 (41%), Gaps = 21/292 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G S L++T+ + D NDN P+F Y V++DE G +
Sbjct: 2780 LTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLVSLDENAQRGTLVVQLNATDLDE 2839
Query: 127 SLTIPLTVPRGLTIFKDIR-AFDRD--------KPNTP--NSDVHYSIVSGNDDGHFALE 175
L + G T K ++ F+ D K N ++V + +D GH
Sbjct: 2840 GLNGEIEYSFGKTQKKKVQDTFELDSVTGEIRVKGNVDFEETEVFRLDIQASDKGHLPWT 2899
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASG-KRIHKEILFPEPIHAIDQDLGVGATLRYE 234
+ + V+ K+ D + E ++ +++ K I D+D G+ + +
Sbjct: 2900 AESRVVI---KIKDINDNRPEIEITSLSTSVPEDAKPGTVISLISIRDKDSGLNGKVICK 2956
Query: 235 LISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
ISG D S+ +++ L + LD E + + + + A+ +P +A +
Sbjct: 2957 -ISG-DVPFDLTPSIEENMYSLVTKGRLDRE---RVAHYDIIITATDCGDPPLSAVKSLT 3011
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ + D+NDN P F + + + +VEN G S+ V A D D EN Y +
Sbjct: 3012 VYVSDVNDNRPVFNQNPFELYLVENNAPGASIFSVSAVDDDLNENALVNYNI 3063
Score = 51.6 bits (118), Expect = 2e-04
Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 26/175 (14%)
Query: 218 IHAIDQDLGVGATLRYELI-----SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D+DL A + Y +I G + ++++ NG + K D + TF
Sbjct: 874 VTASDKDLNENADISYHIIREEGGQGKNAAFLNINAENGQISALKSFDFET-----LKTF 928
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS----------IVENLPNG 322
QV AS +P ++ V++ +LD NDN P V Y +S I N+ G
Sbjct: 929 QFQVVASDSGSPSLSSNVTVKVFILDQNDNAP---VILYPVSSNGSAEGLEEIPRNVNAG 985
Query: 323 FSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVLDREAH 374
V +V A D D G NG + L + F +D +G + T+R+ T D H
Sbjct: 986 HLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEH 1040
Score = 50.4 bits (115), Expect = 4e-04
Identities = 42/154 (27%), Positives = 69/154 (44%), Gaps = 24/154 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P+ S T +++ V DV D + PVF Y + EN + +N T+ E
Sbjct: 208 GRPAKSGTMGIIIQVLDVND-----NSPVFTKEVYSASVNENSPPGTLVTRVNATDLDEG 262
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N + Y E DT ++ F IDP+ G + + D E ++YE+ V+A + +P
Sbjct: 263 ANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASDK---GTIP 319
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
Y V++++KD+NDN P+
Sbjct: 320 LSTYR--------------SVIIKVKDLNDNPPE 339
Score = 50.0 bits (114), Expect = 5e-04
Identities = 68/299 (22%), Positives = 115/299 (38%), Gaps = 25/299 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G S L+VTV + D NDN PIF Y V E G +
Sbjct: 608 LTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKATDLDE 667
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGND---------DGHFALESS 177
+ G +D R FD N ++ + G D D H A +
Sbjct: 668 GANGEIEYFFGGQ--QDRRTFDIFDLNKETGEI--KVKGGIDFEKVEVFKLDVH-ATDKG 722
Query: 178 HKPV----LLLRKVLDYDAGDKEFQLVIMASG-KRIHKEILFPEPIHAIDQDLGVGATLR 232
P+ ++ KVLD + + ++ +++ K I D D G+ +
Sbjct: 723 QPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKVM 782
Query: 233 YELISGNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
L + L S SL L++ LD ++ + + + + A+ P +
Sbjct: 783 CSLSDNSPFDLKPSFQENMYSLVLKQPLDRES-----VSHYDVTITATDCGQPALSDFKT 837
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+ I++ D+NDN P++ + +VEN G + V A+DKD EN + +Y + +G
Sbjct: 838 LSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADISYHIIREEG 896
Score = 48.8 bits (111), Expect = 0.001
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 11/152 (7%)
Query: 211 EILFPEPIHAIDQDLGVG----ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
EI P+ ++ +DLG+ A R+ ++ G + LF L+ NG L++ K +D +
Sbjct: 2607 EIQIGHPVGSVAKDLGLDISTLADRRFRIVPGPNHHLFQLNQDNGVLYVGKNIDRE---E 2663
Query: 267 LQANTFVLQVQAS-QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
L T V + + +PL+ V +E+ D+ND+ P F + I E+ P G
Sbjct: 2664 LCDGTKVCLINLKIVVESPLEIHY--VGVEIADVNDHAPSFPESEQRLEIAEHTPPGTRF 2721
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
A D D +Y+L F ID R
Sbjct: 2722 QIHAARDPDAATLTVRSYKLSH-NDCFDIDIR 2752
Score = 48.4 bits (110), Expect = 0.002
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 9/152 (5%)
Query: 208 IHKEILFPEPIHAIDQDLGVG-ATLR---YELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
I +E+ + I +DLG+ A+L+ Y ++ + LF ++ +G L++ K+LD +
Sbjct: 25 ISEEVKEGTVVGNIAKDLGIDKASLKEREYRIVGASAEPLFRVNREDGILYVSKKLDREV 84
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
++N V+ ++ + L NPL+ V IE+LD+ND+ P F + + I E+ G
Sbjct: 85 ICE-KSNVCVINLK-TVLENPLEIHY--VAIEVLDVNDHSPTFPENEKRLEIFESTSTGA 140
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
A D D G+ Y+L P F ++
Sbjct: 141 RFQLQPARDPDGGQFTVQQYRL-SPNDHFRLE 171
Score = 48.0 bits (109), Expect = 0.002
Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 11/110 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQN 492
L S V V+V +LD NDN PV V SN ++ N G ++ KV+A D D+G N
Sbjct: 942 LSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYN 1001
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASD 540
G +L+ LQ S+ ++ F ++ TG + S E H L + D
Sbjct: 1002 GWLLFALQEVSDHSL---FGLDRYTGQIRTLRSFTETDEAEHKLVILVKD 1048
Score = 47.6 bits (108), Expect = 0.003
Identities = 38/127 (29%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V+V V +LD NDNNP + P ++ S+ +A+ G + K++AVD D G N
Sbjct: 4093 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDLDSGYNA 4152
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYS 551
++ Y L + F++ +TG + S H L V SD S
Sbjct: 4153 LLSYHLSEPKGNNL---FRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNGEPSLSATVS 4209
Query: 552 LAVVTIE 558
+ VV +E
Sbjct: 4210 IEVVVVE 4216
Score = 47.2 bits (107), Expect = 0.003
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P+ S T + +TV DV D + PVF Y + EN ++ +N T+ +
Sbjct: 1368 GKPARSGTMTIKITVLDVNDNM-----PVFAKESYVAVLRENSPIGTTVLQVNATDLDDG 1422
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y N + +R+ F ID G + + D E+KD YE+ ++A
Sbjct: 1423 LNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKA 1472
Score = 47.2 bits (107), Expect = 0.003
Identities = 88/365 (24%), Positives = 147/365 (40%), Gaps = 49/365 (13%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLD 99
+D+D+ + +VK ++ D++ D D+ G + SV + I D+NDN P
Sbjct: 1445 IDADTGEIIVKGQI--DYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 1502
Query: 100 TPYHVTVDELTPTGEKAFIFLIAPIGPSLT------IPLTVPRGL--TIFKDIRAFDRDK 151
T + V E + G + ++ + I VP L T+ ++ +
Sbjct: 1503 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFMLSPTLQANMYSVVTKS 1562
Query: 152 PNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF---QLVIMASGKR 207
+ Y I ++ D G L SSH+ + + V D + EF +
Sbjct: 1563 VLDREHESKYDITITAKDAGDQPL-SSHRTISV--SVSDVNDNSPEFVTNPYTFYVTENN 1619
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELI-SGNDRK----LFSLDSVNGSLFLEKELDLD 262
LF + A D D + + Y +I +GN + +++S NG + K D +
Sbjct: 1620 DPGTTLFS--VSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFDFE 1677
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-------- 314
A+ F QV AS +P ++ V++ +LD NDN P V Y +S
Sbjct: 1678 AQ-----KMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAP---VILYPVSSNGSAEGL 1729
Query: 315 --IVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVL 369
I N+ G V +V A D D G NG + L + F +D +G + T+R+ T
Sbjct: 1730 EEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTET 1789
Query: 370 DREAH 374
D H
Sbjct: 1790 DEAEH 1794
Score = 47.2 bits (107), Expect = 0.003
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P+ S T + +TV DV D + PVF Y + EN ++ +N T+ +
Sbjct: 2122 GKPARSGTMTIKITVLDVNDNM-----PVFAKESYVAVLRENSPIGTTVLQVNATDLDDG 2176
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y N + +R+ F ID G + + D E+KD YE+ ++A
Sbjct: 2177 LNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKA 2226
Score = 47.2 bits (107), Expect = 0.003
Identities = 88/365 (24%), Positives = 147/365 (40%), Gaps = 49/365 (13%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLD 99
+D+D+ + +VK ++ D++ D D+ G + SV + I D+NDN P
Sbjct: 2199 IDADTGEIIVKGQI--DYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 2256
Query: 100 TPYHVTVDELTPTGEKAFIFLIAPIGPSLT------IPLTVPRGL--TIFKDIRAFDRDK 151
T + V E + G + ++ + I VP L T+ ++ +
Sbjct: 2257 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFMLSPTLQANMYSVVTKS 2316
Query: 152 PNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF---QLVIMASGKR 207
+ Y I ++ D G L SSH+ + + V D + EF +
Sbjct: 2317 VLDREHESKYDITITAKDAGDQPL-SSHRTISV--SVSDVNDNSPEFVTNPYTFYVTENN 2373
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELI-SGNDRK----LFSLDSVNGSLFLEKELDLD 262
LF + A D D + + Y +I +GN + +++S NG + K D +
Sbjct: 2374 DPGTTLFS--VSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFDFE 2431
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-------- 314
A+ F QV AS +P ++ V++ +LD NDN P V Y +S
Sbjct: 2432 AQ-----KMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAP---VILYPVSSNGSAEGL 2483
Query: 315 --IVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVL 369
I N+ G V +V A D D G NG + L + F +D +G + T+R+ T
Sbjct: 2484 EEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTET 2543
Query: 370 DREAH 374
D H
Sbjct: 2544 DEAEH 2548
Score = 46.8 bits (106), Expect = 0.005
Identities = 110/486 (22%), Positives = 183/486 (37%), Gaps = 64/486 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IP N+ G + K+ A D D G NG + + ++S +L F ++ G
Sbjct: 2486 IPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ--------EVSDHSL-----FGLDRYTG 2532
Query: 1000 HVIVARSLPP--ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNF----- 1052
+ RS E+E +L I D GN++ + + V VK V F
Sbjct: 2533 QIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVEPKEAFAASDCSKFCPGRR 2592
Query: 1053 --NVEEA-QYTRRV---LGK-VDATDADFGQN----ANLTYFIQPSDTDLPFEISPLTGV 1101
+ E+ RRV +G V + D G + A+ + I P F+++ GV
Sbjct: 2593 GRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLADRRFRIVPGPNHHLFQLNQDNGV 2652
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW- 1160
L V +DRE + DVND++P F ++ LE
Sbjct: 2653 LYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGVEIADVNDHAPSFPESEQRLEIA 2712
Query: 1161 KH-PEADELSNHNFES--VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+H P H + V + N + + + F+ L
Sbjct: 2713 EHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCFDIDIRESEEDKIPFLVLKKPLDREQ 2772
Query: 1218 LPQRK---NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV 1274
Q + G PS S + L + V D D ++PVF Y + ++EN
Sbjct: 2773 KAQHSLTLTALDGGNPSRSGSLNLTIEVLDTND-----NRPVFSKDIYLVSLDENAQRGT 2827
Query: 1275 ELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
+V LN T+ E N ++ Y ++ TF +D G + + + D E + + +
Sbjct: 2828 LVVQLNATDLDEGLNGEIEYSFGKTQKKKVQDTFELDSVTGEIRVKGNVDFEETEVFRLD 2887
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
++A + + LP AE +VV++IKD+NDN P+ + L T++P
Sbjct: 2888 IQASDKGH---LPW----TAES----------RVVIKIKDINDNRPEIEITS--LSTSVP 2928
Query: 1393 TTAPFG 1398
A G
Sbjct: 2929 EDAKPG 2934
Score = 46.4 bits (105), Expect = 0.006
Identities = 56/195 (28%), Positives = 72/195 (36%), Gaps = 35/195 (17%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + V DVNDH P F + + E+ T A D D GQ Y + P+D
Sbjct: 109 VAIEVLDVNDHSPTFPENEKRLEIFESTSTGARFQLQPARDPDGGQFTVQQYRLSPND-H 167
Query: 1091 LPFEISPL-----TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
E+ L + LDRE ++ L + A D G DVN
Sbjct: 168 FRLEVKERGEDRKMPFLILQKALDREAMKEHKLVLTAVDGGRPAKSGTMGIIIQVL-DVN 226
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DNSP V VY A++ EN+P GT V +V N TD
Sbjct: 227 DNSP--------------------------VFTKEVYSASVNENSPPGTLVTRV--NATD 258
Query: 1206 FIGNGNGLILYSLPQ 1220
NG I+YS Q
Sbjct: 259 LDEGANGDIIYSFGQ 273
Score = 46.0 bits (104), Expect = 0.008
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y D ++ FS+D G + + +D + + ++ +
Sbjct: 254 VNATDLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFE-----ENESYEI 308
Query: 275 QVQASQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
VQAS PL T ++ V I++ DLNDN PE E+ ++ S+ E+ G +V + A+D
Sbjct: 309 DVQASDKGTIPLSTYRS-VIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALISASDL 367
Query: 334 D 334
D
Sbjct: 368 D 368
Score = 42.3 bits (95), Expect = 0.099
Identities = 53/215 (24%), Positives = 95/215 (44%), Gaps = 21/215 (9%)
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVT 1241
Y A + EN+PIGTTV +V N TD NG ++YS N + L + + ++
Sbjct: 1397 YVAVLRENSPIGTTVLQV--NATDLDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIV 1454
Query: 1242 VADVPDE--------VEMSDK---PVFISRYYELEI-EENVNAP-VELVSLNLT---EHY 1285
+ E ++ SDK P+ + ++ I + N NAP +E+ S + +
Sbjct: 1455 KGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAVPEDSK 1514
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+ +++ D+ + VI N + + SP + + Y V+ ++ + E
Sbjct: 1515 PGTTVALISVSDKDSGVNGK-VICFINEDVPFMLSPTLQA-NMYSVVTKSVLDR-EHESK 1571
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ I A+D + + V + DVNDNSP+F
Sbjct: 1572 YDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEF 1606
Score = 42.3 bits (95), Expect = 0.099
Identities = 53/215 (24%), Positives = 95/215 (44%), Gaps = 21/215 (9%)
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVT 1241
Y A + EN+PIGTTV +V N TD NG ++YS N + L + + ++
Sbjct: 2151 YVAVLRENSPIGTTVLQV--NATDLDDGLNGEVVYSFGNNVNHRLRKLFEIDADTGEIIV 2208
Query: 1242 VADVPDE--------VEMSDK---PVFISRYYELEI-EENVNAP-VELVSLNLT---EHY 1285
+ E ++ SDK P+ + ++ I + N NAP +E+ S + +
Sbjct: 2209 KGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAVPEDSK 2268
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+ +++ D+ + VI N + + SP + + Y V+ ++ + E
Sbjct: 2269 PGTTVALISVSDKDSGVNGK-VICFINEDVPFMLSPTLQA-NMYSVVTKSVLDR-EHESK 2325
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ I A+D + + V + DVNDNSP+F
Sbjct: 2326 YDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEF 2360
Score = 41.9 bits (94), Expect = 0.13
Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT----IPL 132
+SA S+TVY+ DVNDN P+F P+ + + E G A IF ++ + L +
Sbjct: 3004 LSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPG--ASIFSVSAVDDDLNENALVNY 3061
Query: 133 TVPRGLTIFKDIRAF 147
+ RG + D+ AF
Sbjct: 3062 NIIRGDGLLNDLTAF 3076
Score = 39.5 bits (88), Expect = 0.69
Identities = 54/237 (22%), Positives = 95/237 (40%), Gaps = 15/237 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L F + + + D NDN P + S + + +++NA G+ I V A D DL +N + Y
Sbjct: 832 LSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAP-GSQIFSVTASDKDLNENADISYH 890
Query: 499 LQRTSNLTITSP--FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
+ R + IN G +S +S E V ASD + ++ V
Sbjct: 891 IIREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKV 950
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD--LLH 612
++ + A + NV G V ++R DA D+ Y+ LL
Sbjct: 951 FILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDA----DIGYNGWLLF 1006
Query: 613 GYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+E F ++ +G I + + + + + +++N N+S+ ATV V
Sbjct: 1007 ALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VILVKDNGNVSLSATATVLV 1062
Score = 37.5 bits (83), Expect = 2.8
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 221 IDQDLGVGATLR----YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ +DLG+ A + ++SG+ F L + NG L + + +D + E +A V+
Sbjct: 1199 VAKDLGLDANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDRE-EVCERAGACVINT 1256
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQ 327
+ L NPL+ V +E+LD+ND+ P F V+ + I E+ LP LQ
Sbjct: 1257 KIV-LENPLEVHY--VAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQ 1305
Score = 37.5 bits (83), Expect = 2.8
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 221 IDQDLGVGATLR----YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ +DLG+ A + ++SG+ F L + NG L + + +D + E +A V+
Sbjct: 1953 VAKDLGLDANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDRE-EVCERAGACVINT 2010
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQ 327
+ L NPL+ V +E+LD+ND+ P F V+ + I E+ LP LQ
Sbjct: 2011 KIV-LENPLEVHY--VAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQ 2059
Score = 36.3 bits (80), Expect = 6.5
Identities = 17/47 (36%), Positives = 26/47 (55%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+V G +S+ +V V + DVNDN P FL+ ++ V E +P G
Sbjct: 3570 IVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVG 3616
Score = 36.3 bits (80), Expect = 6.5
Identities = 17/47 (36%), Positives = 26/47 (55%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+V G +S+ +V V + DVNDN P FL+ ++ V E +P G
Sbjct: 3973 IVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVG 4019
>UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whole
genome shotgun sequence; n=2; Euteleostomi|Rep:
Chromosome undetermined SCAF11948, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 3085
Score = 164 bits (398), Expect = 2e-38
Identities = 181/688 (26%), Positives = 307/688 (44%), Gaps = 72/688 (10%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
AT+ +++ GN +F +D G++ + K LD + Q + + L VQA+ + K A
Sbjct: 1410 ATVWFDITGGNSESVFHVDKTVGTIIIAKPLDAE-----QQSFYNLTVQAT---DGTKAA 1461
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-D 347
A+V + +LD NDN P F Y +++ E++P V+QV+A D+D+ ++ Q D
Sbjct: 1462 FAQVHVTVLDTNDNAPIFSQPTYEVTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSID 1521
Query: 348 PKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRR 405
P F I P G T+ LD EA +L + T S ++A + R
Sbjct: 1522 PSSMRFFHIHPTLG--TIHTLQSLDHEA-CALHIL------------TITVSLKLALFAR 1566
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
A KT K K ++ E+ + M+ V +EV D ND+ P+F S Y
Sbjct: 1567 GFHGYMAVNNKT------KTVKKVKDQEFPYRKNMARVLIEVK--DVNDHVPIFTRST-Y 1617
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
E S+ ++ VG+ + +V A+D D G+N V Y ++ + + F I P G ++++
Sbjct: 1618 EGSVCESSAVGSAVVQVSALDKDKGENADVQYSIESGNK---GNTFHIEPILGIITISHD 1674
Query: 526 PILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVG 583
L G + L V A+D+ + P + +V I VT P F Y +
Sbjct: 1675 LNLSSIGHYVLTVRATDKGSPPLS---TTTMVHISVTLSDNA----APKFPQEEYLAVIT 1727
Query: 584 SNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMY 643
NV +GTS+ I V+ A Q ++YD+ G +GV F + + SGVIT L Y
Sbjct: 1728 ENVAVGTSI--ITVS-AVSQTTLTYDIKQGDADGV-FQINQYSGVITTRKALDYEKTASY 1783
Query: 644 DFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT 703
A+ A ++ A + + D ND V + + +H + A A + +
Sbjct: 1784 SLIVQAVNM-AGMASNATAIIQLKDENDNPPVFQQ-----LRYHGSISEAAAVNSVVLNP 1837
Query: 704 NMSSIYGNGTG---NVRFLIANQ--QDVTDDIAIAEDGT--IFTQKPLDREKRDVYRMTV 756
+ S + T N L+ Q +DV + GT I T LD E ++ V
Sbjct: 1838 DDSPLVIKATDADRNENALLVYQIVEDVAKMFFAVDSGTGSIRTIASLDHETLAIFHFHV 1897
Query: 757 -IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
+ + + ++ G +VTI + D ND+PP F ++YE ++ + G E+ +KAT
Sbjct: 1898 FVRDSGRPQLTADGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVEVLQ---VKAT 1954
Query: 816 DADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
D DE + Y+L E F ++ +G + + E+ + V G SS
Sbjct: 1955 DPDEDVSRNLTYSLTNGVLEHFAIEPLSGTIVVKQSNFSNERFLFG----VRVSDGQFSS 2010
Query: 876 EAELIIMIGDENDNKPEFNQIEENSKVR 903
A + +++ + D+ F+Q +S ++
Sbjct: 2011 TALVNVLVREALDSGLSFSQSLYSSTIQ 2038
Score = 140 bits (338), Expect = 4e-31
Identities = 127/437 (29%), Positives = 197/437 (45%), Gaps = 32/437 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + DANDN P F+ Y + N +GT + +V A D D G NG V Y L LT
Sbjct: 804 VFIEDANDNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAYSL-----LT 858
Query: 507 ITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
T+ F IN +G V VA L L VEA D+ S+R +V T++V
Sbjct: 859 ATANFGINSTSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQR---FSVTTLKVVLEDV 915
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P F+ + Y+ ++ +GT + + D V Y L + Y F V
Sbjct: 916 NDCP--PVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLANDYNGW--FEV 971
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI--VTNATVHVVDVNDERGVLLKGA 680
+ SG I ++ +L + Y+ A +++ VT+ V VVDVN+ +
Sbjct: 972 DRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNAPY-FS 1030
Query: 681 HSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
H + VKEN+ G + Q+ G G +++ I + + E G I+
Sbjct: 1031 HFALKATVKENARIGTTLLQV--AAQDDDVGR-DGEIQYSIRDGSGLGRFAINEETGVIY 1087
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T LDRE +D Y +TV A ++GV+ V + +ED NDN P+ A Y+ + EN
Sbjct: 1088 TTDTLDRETKDSYWLTVYAT-DRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSSVQEN 1146
Query: 800 SKIGTEIKMDNIIKATDADE---GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
S G + I+A D DE L + + G + +F ++ +TG++ LDRE
Sbjct: 1147 SPEGVSVVQ---IQAQDPDETPLTAEKLSFHIVSGNPQNLFAINSHTGLITTTSRKLDRE 1203
Query: 857 KKIMYKL--SLVARDTG 871
++ + L S+ RD G
Sbjct: 1204 QQTEHNLEASVCVRDAG 1220
Score = 136 bits (329), Expect = 4e-30
Identities = 167/698 (23%), Positives = 294/698 (42%), Gaps = 45/698 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y IS F ++ +G + + LD D +++FV V+
Sbjct: 480 VSAQDGDDGENGYITYS-ISSLGALPFQINQFSGVITTTEPLDFD----FSSDSFVFIVR 534
Query: 278 ASQLNNPLKT-AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +P + ++ V I + ++NDN P FE + I +LP + V A D D+
Sbjct: 535 ASDWGSPYRRESEVYVTIHVKNVNDNQPLFEKTACHGVISRDLPADQVITTVSAIDIDEL 594
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
++ + G F+++P SG L+++ V A++ +K+ A + + +
Sbjct: 595 ALVKYKIVSGNTLGLFNLNPDSGVLSLQRSLVPAVSANA-FSLKITATDGENLSEPMYVN 653
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+ + + N +K+ K++ + F+++ N
Sbjct: 654 IS-VVEGKSFSKNINCKETMVAQRLAEKLLKKSKGSAAPKSE-EGFIDI----FSINRQT 707
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P F + + +++ + VG+ + +V A D D G NG +LY + S+ F ++ +
Sbjct: 708 PQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQILYSI---SDGNPDDCFTMDTD 764
Query: 517 TGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMG 575
TG +SV E + H L P + + L V IE N P G
Sbjct: 765 TGLISVLLPLDREKKDHYLLNLTIYDLGRPPKSAWHLLTVFIE---DANDNAPQFLQEGG 821
Query: 576 APYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVD 633
Y + N IGT V Q+ DA +V+Y LL F + SGV+ V
Sbjct: 822 --YTVVLPENTAIGTDVIQVGATDRDAGPNGEVAYSLLTATAN---FGINSTSGVVYVAG 876
Query: 634 DLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
L R ++ + A ++ + VT V + DVND V + + +++
Sbjct: 877 QLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVLEDVNDCPPVFIPSVYKTRA--LED 934
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
G + + G G G V++ +AN + ++ G I K LD E +
Sbjct: 935 LPVGTVLAWL--ETQDPDLGPG-GQVQYSLANDYNGWFEVD-RTSGAIRLMKELDYETQQ 990
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIED--ENDNPPVFEHATYEGFIMENSKIGTEIKM 808
Y ++V A+ ++ + V + + D EN N P F H + + EN++IGT +
Sbjct: 991 FYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNAPYFSHFALKATVKENARIGTTLLQ 1050
Query: 809 DNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
+ A D D G + Y++ G G F ++E TGV+ + D+LDRE K Y L++ A
Sbjct: 1051 ---VAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETGVI-YTTDTLDRETKDSYWLTVYA 1106
Query: 868 RDTGGLSSEAEL--IIMIGDENDNKPEFNQIEENSKVR 903
D G + A + + + D NDN P ++ +S V+
Sbjct: 1107 TDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSSVQ 1144
Score = 132 bits (320), Expect = 5e-29
Identities = 125/474 (26%), Positives = 211/474 (44%), Gaps = 40/474 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+S+ V+V+L+D NDN P F + Y S++S+ G ++ +V+A DPD G N + Y +
Sbjct: 2626 VSYATVQVSLVDENDNAPHFWATE-YRASVRSSVAEGFLLTQVQASDPDAGTNARITYSI 2684
Query: 500 QRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
S++ +T +I+P+ G + A ++ FV+A D +P+ R+SL V +
Sbjct: 2685 YSDSHVPVTDILEIDPDNGWIVTKGAFGHLMNSVLYFFVKAEDG-GHPA--RHSLVSVYV 2741
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHG-- 613
V IP F+ YEF V + +GT+VG +R+ + + L++G
Sbjct: 2742 HVLSPAAS----IPSFLQQHYEFSVAEDTSVGTAVGMLRLKTPPGYASLSAVFSLVNGAM 2797
Query: 614 --YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDV 669
Y + F VE+ +G+I + L Y F+A A + A L V + V V +D
Sbjct: 2798 EKYNQDGVFVVEKDTGLIRLNKPLDHELIKEYYFKATATVQQAKLDSVASVDVQVKVLDR 2857
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLI-------A 721
ND + + + + G + +I G VR+ + +
Sbjct: 2858 NDNKPEFVTESFEAAVME------GVPLATRILQVRALDADSGANGQVRYSLGGLIQSES 2911
Query: 722 NQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
Q+ + + +I ++ G I T LD E Y TV+A + S + VT+ + D
Sbjct: 2912 QQETLFNTFSIDSQSGWISTLTNLDHETSSSYVFTVVASDFGEITSFSATATVTVVVTDV 2971
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEG-KEMFD 838
NDNPP F Y G + E S G + + D D TN Y + G + F
Sbjct: 2972 NDNPPRFLEQRYFGSVQEGSPPGEVVA---ALDTRDNDGSATNRHVSYHITGGNYRGSFA 3028
Query: 839 VDENTGVVK-FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+ G K ++ LDRE++ +Y++++ A D G + + + D NDN P
Sbjct: 3029 LGLVQGEWKLYVKFRLDREERSLYRINVSASD-GLFVCHTLVHVSVLDANDNSP 3081
Score = 116 bits (280), Expect = 4e-24
Identities = 131/493 (26%), Positives = 210/493 (42%), Gaps = 41/493 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D ++ V V+V + D NDN PVFV Y +++ +A+ GT I +V A+D D G NG V
Sbjct: 2107 DHLRVARVLVKVQVEDVNDNVPVFVGLPYYA-AVQVDAEPGTAIFRVMAIDQDKGINGHV 2165
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPSERRYSL 552
Y L L F+IN TG +S+ ES + + + + A D + P
Sbjct: 2166 SYYL-----LDDHGHFEINKLTGILSLKKAFESDLSNVEYQMVIYARDHGSIPLSSTTEF 2220
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
+ + NK +P F Y V +V + T V I Q+ + Y ++
Sbjct: 2221 PITVV--------NKA-MPVFDKPFYSISVNEDVAVHTPVLGINATSPKGQS-IIYTIVD 2270
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G + + F + +GVI V+ L Y+ A + V V DVND
Sbjct: 2271 G-DPSLQFDIGFDTGVIAVIHPLDHETAARYNLTVRATDCLTGAHAEVDVDVAVKDVNDN 2329
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + K A+ ++ S IG H + + + + + I + + TD
Sbjct: 2330 QPLFKKMAYQVVL------SETVMIGTPALHVSATDKDSDKNNVIHYQIFSDHNNTDYFH 2383
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I + G I T + LD E + VIA N G + VT+ + D NDNPPVF
Sbjct: 2384 IDSSSGLILTARMLDHELVQKFDFVVIATDN-GFPPLSSEVSVTVMVSDINDNPPVFNQL 2442
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKFI 849
YE ++ E + G + ++A+DAD Y+ L G K +F +D+ TG+V +
Sbjct: 2443 LYEAYVDELAPRGHFV---TCVQASDADSSDYEKLEYSILSGNEKLVFMLDKMTGIVT-L 2498
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
+ + Y L++ D G +S A++ I + N P F Q ++V K
Sbjct: 2499 SSRYKQRMEPAYSLNISVSD-GVFTSTAQVHIKVSQGNLYAPVFEQNVYEAQV------K 2551
Query: 910 LNGTAGFTIIEVK 922
N G +++VK
Sbjct: 2552 ENSVVGTRVVQVK 2564
Score = 102 bits (245), Expect = 7e-20
Identities = 162/730 (22%), Positives = 292/730 (40%), Gaps = 51/730 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L ++ V V +LD ND P+F P+ Y ++ + + T I +V A D D+G NG
Sbjct: 124 DALLETWTKVSVQVLDMNDLRPLFSPTT-YSVTIMESTPLRTSIAQVTATDADIGSNGEF 182
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPAN--PSERRYS 551
Y L+ +L F ++P +G V ++ ++ R H L + A D+ + S
Sbjct: 183 YYFLKNKMDL-----FAVHPTSGVVLLSGKLNVDERYQHDLEILAVDRGMKLYGNNGVSS 237
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
A + + V R + + P I +P W +N I +V + D +V ++
Sbjct: 238 TAKLIVHVERVNE-HAPVISVVNSSP---WSHANSPI-YAVVTVEDPDPGLNGEVDSVVI 292
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G + F +E + N + + A+ +V VV + D
Sbjct: 293 LGGDLSEKFFLERSEENEFFIRATESLNWETHPRGCNLTLQAADRGTPQKVSVKVVQIMD 352
Query: 672 ERGVLLKGAHSPIIFHVK--ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
E+ + +++V E S + Q+ S Y V + + D
Sbjct: 353 EKQSKVAAMFEKEVYNVSLSEFSPPGTVVQVVKIKPESSY------VEYTLTPSADSAFF 406
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G I T + + ++++ V+ E + + + QV + I+D NDN P F
Sbjct: 407 RVNGVTGVISTTQWFTGVSQSLFKLDVL-EMDSELKA-----QVQVAIQDANDNTPTFHQ 460
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
++YE + E+ +GT + + A D D+G N Y++ G F +++ +GV+
Sbjct: 461 SSYEILVNESVPVGTSVL---TVSAQDGDDGENGYITYSISSLGALPFQINQFSGVIT-T 516
Query: 850 GDSLDRE-KKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENSKVR-- 903
+ LD + + + A D G SE + I + + NDN+P F + + +
Sbjct: 517 TEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKNVNDNQPLFEKTACHGVISRD 576
Query: 904 IHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
+ + + + I E+ + + LG L P++ G ++ + + S
Sbjct: 577 LPADQVITTVSAIDIDELALVKYKIVSGNTLGLFNLNPDS---GVLSLQRSLVPAVSANA 633
Query: 964 GQIRY-EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDG 1022
++ + E P ++ +E K F N +VA+ L +E L S
Sbjct: 634 FSLKITATDGENLSEPMYVNISVVEGKS-FSKNINCKETMVAQRL---AEKLLKKSKGSA 689
Query: 1023 GNLNDNISVRVFVKDVNDHFPVFKKTW-YNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
++ + +F +N P F K + + V E + +V A D D G N +
Sbjct: 690 APKSEEGFIDIF--SINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQIL 747
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
Y I + D F + TG++SV LDRE +D Y+L + D G
Sbjct: 748 YSISDGNPDDCFTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLG-RPPKSAWHLLTVFI 806
Query: 1142 XDVNDNSPKF 1151
D NDN+P+F
Sbjct: 807 EDANDNAPQF 816
Score = 99 bits (238), Expect = 5e-19
Identities = 123/486 (25%), Positives = 195/486 (40%), Gaps = 43/486 (8%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
NI D S V + + N PVF N+YE +K N+ VGT + +VKA D D G
Sbjct: 2513 NISVSDGVFTSTAQVHIKVSQGNLYAPVF-EQNVYEAQVKENSVVGTRVVQVKATDSDPG 2571
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
G V Y N F I+ N G ++ AE E +V S A +
Sbjct: 2572 VFGRVTYSFV---NDVGRERFSIDAN-GQITTAEKLDREDPSNQYVVVS-VAAQDAGGHV 2626
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSY 608
S A V + + + P F Y V S+V G + Q++ +D A ++Y
Sbjct: 2627 SYATVQVSLV----DENDNAPHFWATEYRASVRSSVAEGFLLTQVQASDPDAGTNARITY 2682
Query: 609 DLLHGYEEGVPFAVE---ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH 665
+ V +E + ++T N +Y F + + + VH
Sbjct: 2683 SIYSDSHVPVTDILEIDPDNGWIVTKGAFGHLMNSVLYFFVKAEDGGHPARHSLVSVYVH 2742
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-- 722
V+ L+ + F V E+ S G A+G + + + G + + F + N
Sbjct: 2743 VLSPAASIPSFLQQHYE---FSVAEDTSVGTAVGML---RLKTPPGYASLSAVFSLVNGA 2796
Query: 723 -QQDVTDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
++ D + + E G I KPLD E Y A + + V + + D
Sbjct: 2797 MEKYNQDGVFVVEKDTGLIRLNKPLDHELIKEYYFKATATVQQAKLDSVASVDVQVKVLD 2856
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKE 835
NDN P F ++E +ME + T I ++A DAD G N Y+L G E ++
Sbjct: 2857 RNDNKPEFVTESFEAAVMEGVPLATRILQ---VRALDADSGANGQVRYSLGGLIQSESQQ 2913
Query: 836 -----MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS---EAELIIMIGDEN 887
F +D +G + + +LD E Y ++VA D G ++S A + +++ D N
Sbjct: 2914 ETLFNTFSIDSQSGWISTL-TNLDHETSSSYVFTVVASDFGEITSFSATATVTVVVTDVN 2972
Query: 888 DNKPEF 893
DN P F
Sbjct: 2973 DNPPRF 2978
Score = 88.2 bits (209), Expect = 2e-15
Identities = 159/700 (22%), Positives = 283/700 (40%), Gaps = 84/700 (12%)
Query: 736 GTIFTQKPLDRE-KRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I T +PLD + D + V A ++ + +Y VTI++++ NDN P+FE
Sbjct: 512 GVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVY-VTIHVKNVNDNQPLFEKTACH 570
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDS 852
G I + I + A D DE AL Y + G +F+++ ++GV+
Sbjct: 571 GVISRDLPADQVI---TTVSAIDIDE--LALVKYKIVSGNTLGLFNLNPDSGVLSLQRSL 625
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET--KL 910
+ + L + A D LS + I + + N E R+ + K
Sbjct: 626 VPAVSANAFSLKITATDGENLSEPMYVNISVVEGKSFSKNINCKETMVAQRLAEKLLKKS 685
Query: 911 NGTAGFT----IIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQ 965
G+A I++ N+ + P + + E++ +G+++ +++A D D+G NGQ
Sbjct: 686 KGSAAPKSEEGFIDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQ 745
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG 1023
I Y + + D F ++ G + V L E + + LN++ D G
Sbjct: 746 ILYSISDG--------NPDDC-----FTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLG 792
Query: 1024 NLNDNI--SVRVFVKDVNDHFPVF-KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
+ + VF++D ND+ P F ++ Y + E + +V ATD D G N +
Sbjct: 793 RPPKSAWHLLTVFIEDANDNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEV 852
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG-XXXXXXXXXXXXX 1139
Y + + + F I+ +GV+ V G+LDRE + L V ARD
Sbjct: 853 AYSLLTATAN--FGINSTSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKV 910
Query: 1140 XXXDVNDNSPKFY-------AFDEL-----LEWKHPEADELSNHNFESVMMIPVYKATIE 1187
DVND P F A ++L L W + +L + Y E
Sbjct: 911 VLEDVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLANDYNGWFE 970
Query: 1188 ENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD 1247
+ T+ A + D+ Y+L + + + LS T++ V V DV +
Sbjct: 971 VDR---TSGAIRLMKELDY----ETQQFYNLSVKAKDRGKPVALLSVTSV-EVEVVDVNE 1022
Query: 1248 EVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRT 1305
+ + P F + ++EN L+ + + + +++Y I + + + R
Sbjct: 1023 NL---NAPYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSI--RDGSGLGR- 1076
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
F I+ G +Y + DRE KD+Y + V Y V+ +
Sbjct: 1077 FAINEETGVIYTTDTLDRETKDSYWLTV---------------YATDRGVVPQFA--TIA 1119
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
V V+++DVNDN+P +++ +P G V+Q++
Sbjct: 1120 VFVQVEDVNDNAP--LTSEAMYDSSVQENSPEGVSVVQIQ 1157
Score = 88.2 bits (209), Expect = 2e-15
Identities = 108/437 (24%), Positives = 178/437 (40%), Gaps = 41/437 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q S ++V L D ND PVF+PS +Y+ + VGTV+ ++ DPDLG G V Y
Sbjct: 901 QRFSVTTLKVVLEDVNDCPPVFIPS-VYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQY 959
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
L N F+++ +G + + + L+ F S + + + L+V ++
Sbjct: 960 SLANDYN----GWFEVDRTSGAIRLMKE--LDYETQQFYNLSVKAKDRGKPVALLSVTSV 1013
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYE 615
EV + P F + V N IGT++ Q+ +D ++ Y + G
Sbjct: 1014 EVEVVDVNENLNAPYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSG 1073
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT-VHVVDVNDERG 674
G FA+ E +GVI D L R + Y A T A V V DVND
Sbjct: 1074 LG-RFAINEETGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAP 1132
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ + + V+ENS G ++ QI + + F I + +
Sbjct: 1133 LTSEAMYDS---SVQENSPEGVSVVQIQAQDPDETPLTAE-KLSFHIVSGNPQNLFAINS 1188
Query: 734 EDGTI-FTQKPLDREKRDVYRMTV-IAEFNKGV---------------ISGAG------I 770
G I T + LDRE++ + + + + GV +S +G +
Sbjct: 1189 HTGLITTTSRKLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSV 1248
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
VT+ + D+NDN P+F Y+ + E + + + A D D+G N+ Y++
Sbjct: 1249 VWVTVRVLDDNDNKPIFPEKVYQVKLAERERRKKAEPIYRVF-AYDGDQGPNSDLSYSIA 1307
Query: 831 -GEGKEMFDVDENTGVV 846
G F +D T V+
Sbjct: 1308 DGNEDAKFFIDPKTAVL 1324
Score = 87.0 bits (206), Expect = 3e-15
Identities = 112/466 (24%), Positives = 180/466 (38%), Gaps = 37/466 (7%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
E + N PVF Y S+ + V T + + A P GQ+ ++Y +
Sbjct: 2219 EFPITVVNKAMPVF-DKPFYSISVNEDVAVHTPVLGINATSPK-GQS--IIYTIVDGDP- 2273
Query: 506 TITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F I +TG ++V E R+ L V A+D A ++V
Sbjct: 2274 --SLQFDIGFDTGVIAVIHPLDHETAARYNLTVRATDCLTG--------AHAEVDVDVAV 2323
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFA 621
K + P F Y+ + V IGT + D + + N + Y + + F
Sbjct: 2324 KDVNDNQPLFKKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQIFSDHNNTDYFH 2383
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGA 680
++ SG+I L +DF +A LS + TV V D+ND V +
Sbjct: 2384 IDSSSGLILTARMLDHELVQKFDFVVIATDNGFPPLSSEVSVTVMVSDINDNPPVFNQLL 2443
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ + + Q + SS Y + + I + + + G +
Sbjct: 2444 YEAYVDELAPRGHFVTCVQASDAD-SSDYEK----LEYSILSGNEKLVFMLDKMTGIVTL 2498
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
+ Y + + + GV + QV I + N PVFE YE + ENS
Sbjct: 2499 SSRYKQRMEPAYSLNI--SVSDGVFTSTA--QVHIKVSQGNLYAPVFEQNVYEAQVKENS 2554
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGDSLDRE--K 857
+GT + +KATD+D G Y+ + G+E F +D N + + LDRE
Sbjct: 2555 VVGTRVVQ---VKATDSDPGVFGRVTYSFVNDVGRERFSIDANGQITT--AEKLDREDPS 2609
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+S+ A+D GG S A + + + DENDN P F E + VR
Sbjct: 2610 NQYVVVSVAAQDAGGHVSYATVQVSLVDENDNAPHFWATEYRASVR 2655
Score = 86.6 bits (205), Expect = 5e-15
Identities = 127/490 (25%), Positives = 205/490 (41%), Gaps = 89/490 (18%)
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
G ++PEN IGT +I++ A D D+G NG++ Y S L+A A F I
Sbjct: 821 GYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAY----------SLLTATA-----NFGI 865
Query: 995 NERHGHVIVARSLPPE--SEFRLNISALD----GGNLNDNISVRVFVKDVNDHFPVFKKT 1048
N G V VA L E S F L + A D G +++V ++DVND PVF +
Sbjct: 866 NSTSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVLEDVNDCPPVFIPS 925
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
Y E VL ++ D D G + Y + +D + FE+ +G + + EL
Sbjct: 926 VYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSL-ANDYNGWFEVDRTSGAIRLMKEL 984
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND--NSPKFYAFDELLEWKHPEAD 1166
D ET+ Y L+V A+D G DVN+ N+P F F
Sbjct: 985 DYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNAPYFSHF------------ 1032
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---------IGNGNGL---- 1213
KAT++ENA IGTT+ +V A D D I +G+GL
Sbjct: 1033 --------------ALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSGLGRFA 1078
Query: 1214 ------ILYSLP--QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD----KPVFISRY 1261
++Y+ R+ + + L ++ ++ A + V++ D P+
Sbjct: 1079 INEETGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAM 1138
Query: 1262 YELEIEENVNAPVELVSLNLTEHYEN----FKMRYYILNENDTDIRRTFVIDPRNGTLYL 1317
Y+ ++EN V +V + + E K+ ++I++ N ++ F I+ G +
Sbjct: 1139 YDSSVQENSPEGVSVVQIQAQDPDETPLTAEKLSFHIVSGNPQNL---FAINSHTGLITT 1195
Query: 1318 V-RSPDREVKDTYEV---IVRAERQKYSRELPHMIYPVAEDVLEG--MTKYDVK-VVVRI 1370
R DRE + + + + + + R ++P+ V + K+ V V VR+
Sbjct: 1196 TSRKLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSVVWVTVRV 1255
Query: 1371 KDVNDNSPKF 1380
D NDN P F
Sbjct: 1256 LDDNDNKPIF 1265
Score = 81.0 bits (191), Expect = 2e-13
Identities = 109/466 (23%), Positives = 189/466 (40%), Gaps = 54/466 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+G ++Y + G+ F+++ G ++ LD + + +++ L V
Sbjct: 1051 VAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETGVIYTTDTLDRETK-----DSYWLTVY 1105
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ-- 335
A+ + A V +++ D+NDN P Y+ S+ EN P G SV+Q+ A D D+
Sbjct: 1106 ATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSSVQENSPEGVSVVQIQAQDPDETP 1165
Query: 336 --GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
E F +P+ F+I+ +G +T ++ LDRE + ++ + V
Sbjct: 1166 LTAEKLSFHIVSGNPQNLFAINSHTGLITTTSRK-LDREQQTEHNLEASVCVRDAGV--- 1221
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
R + W PL+ V G ++ S V V V +LD N
Sbjct: 1222 ---WYRASHWSVWPLQ----------VMVSDSGPSPKH---------SVVWVTVRVLDDN 1259
Query: 454 DNNPVFVPSNLYEFSM--KSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
DN P+F P +Y+ + + K I +V A D D G N + Y + + + F
Sbjct: 1260 DNKPIF-PEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSIADGNE---DAKF 1315
Query: 512 KINPNTGTVSVAES------PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
I+P T +S ++ IL + + + N ++ S A + IE R
Sbjct: 1316 FIDPKTAVLSSRKAFAAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLHIEWVRRPPA 1375
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEER 625
P + F Y F V + + VG + + + V +D+ G E V F V++
Sbjct: 1376 GPPLL--FDQPFYNFTVMESDKVSEMVGVVSLRRS--AATVWFDITGGNSESV-FHVDKT 1430
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G I + L + Y+ A + + V V+D ND
Sbjct: 1431 VGTIIIAKPLDAEQQSFYNLTVQA--TDGTKAAFAQVHVTVLDTND 1474
Score = 76.2 bits (179), Expect = 7e-12
Identities = 141/576 (24%), Positives = 233/576 (40%), Gaps = 91/576 (15%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L +I EN+ +GT+II ++A+ + + Y+ AD + F IN+
Sbjct: 1723 LAVITENVAVGTSIITVSAVSQTT-----LTYDIKQG--------DADGV-----FQINQ 1764
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + ++L E + + L + A++ + N + + +KD ND+ PVF++ Y+ ++
Sbjct: 1765 YSGVITTRKALDYEKTASYSLIVQAVNMAGMASNATAIIQLKDENDNPPVFQQLRYHGSI 1824
Query: 1055 EEAQYTRRVLGKVD-------ATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
EA V+ D ATDAD +NA L Y I + F + TG +
Sbjct: 1825 SEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIVEDVAKMFFAVDSGTGSIRTIAS 1884
Query: 1108 LDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKF-------------YA 1153
LD ET + V RD+G D ND+ P+F YA
Sbjct: 1885 LDHETLAIFHFHVFVRDSGRPQLTADGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYA 1944
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
E+L+ K + DE + N + V + E P+ T+ ++F N
Sbjct: 1945 GVEVLQVKATDPDEDVSRNLTYSLTNGVLEHFAIE--PLSGTIV---VKQSNF---SNER 1996
Query: 1214 ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
L+ + Q SSTA++ V V + D +S F Y I+EN +
Sbjct: 1997 FLFGVRVSDGQ-------FSSTALVNVLVREALDS-GLS----FSQSLYSSTIQENESGI 2044
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR-SPDREVKDTYEVI 1332
++ +N + N + Y +LN F I P +G + + DRE +++YE++
Sbjct: 2045 TQVAVVNALGNQANEPIVYTLLNGG-----MYFKIRPTSGVIQTTGVAFDREEQESYELV 2099
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
V A RE H+ VA V V V+++DVNDN P F P A+
Sbjct: 2100 VEAR-----REDDHL--RVAR----------VLVKVQVEDVNDNVPVFV--GLPYYAAVQ 2140
Query: 1393 TTAPFGYQVMQLKGAIGHHPTASRTVRADTDELVFFERLSLNGLTS-PQATDSDIGINAD 1451
A G + ++ D+ FE L G+ S +A +SD+ ++
Sbjct: 2141 VDAEPGTAIFRVMAIDQDKGINGHVSYYLLDDHGHFEINKLTGILSLKKAFESDL---SN 2197
Query: 1452 IRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+ YQ++ +I P+S T + A VF
Sbjct: 2198 VEYQMVIYARDHGSI-PLSSTTEFPITVVNKAMPVF 2232
Score = 74.1 bits (174), Expect = 3e-11
Identities = 108/405 (26%), Positives = 177/405 (43%), Gaps = 58/405 (14%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT I ++ A+D D G+NG + Y Y+ L+ +F IN+ G + + ++
Sbjct: 2146 GTAIFRVMAIDQDKGINGHVSY------YL---------LDDHGHFEINKLTGILSLKKA 2190
Query: 1007 LPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRR 1062
+ E+++ I A D G++ + + + VN PVF K +Y+ +V E+
Sbjct: 2191 FESDLSNVEYQMVIYARDHGSIPLSSTTEFPITVVNKAMPVFDKPFYSISVNEDVAVHTP 2250
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
VLG ++AT GQ+ + Y I D L F+I TGV++V LD ET +Y LTV A
Sbjct: 2251 VLG-INATSPK-GQS--IIYTIVDGDPSLQFDIGFDTGVIAVIHPLDHETAARYNLTVRA 2306
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
D DVNDN P F K LS + V
Sbjct: 2307 TD--CLTGAHAEVDVDVAVKDVNDNQPLFK--------KMAYQVVLSETVMIGTPALHV- 2355
Query: 1183 KATIEENAPIGTTVAKVFA--NDTDF--IGNGNGLIL------YSLPQRKN----QQNLG 1228
AT +++ ++F+ N+TD+ I + +GLIL + L Q+ + + G
Sbjct: 2356 SATDKDSDKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIATDNG 2415
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP--VELVSLNLTEHYE 1286
P LSS + V V+D+ D + PVF YE ++E V V + + +
Sbjct: 2416 FPPLSSEVSVTVMVSDIND-----NPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSSD 2470
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
K+ Y IL+ N+ + F++D G + L + ++ Y +
Sbjct: 2471 YEKLEYSILSGNE---KLVFMLDKMTGIVTLSSRYKQRMEPAYSL 2512
Score = 73.3 bits (172), Expect = 5e-11
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 16/190 (8%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ E + IGT + ++A D DS N I Y+ S+ + D YF I+
Sbjct: 2341 VLSETVMIGTPALHVSATDKDSDKNNVIHYQIFSD------HNNTD------YFHIDSSS 2388
Query: 999 GHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G ++ AR L E +F + A D G L+ +SV V V D+ND+ PVF + Y V
Sbjct: 2389 GLILTARMLDHELVQKFDFVVIATDNGFPPLSSEVSVTVMVSDINDNPPVFNQLLYEAYV 2448
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+E + V A+DAD L Y I + L F + +TG+++++ + E
Sbjct: 2449 DELAPRGHFVTCVQASDADSSDYEKLEYSILSGNEKLVFMLDKMTGIVTLSSRYKQRMEP 2508
Query: 1115 KYILTVVARD 1124
Y L + D
Sbjct: 2509 AYSLNISVSD 2518
Score = 72.1 bits (169), Expect = 1e-10
Identities = 86/347 (24%), Positives = 134/347 (38%), Gaps = 17/347 (4%)
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLND---NISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G + V L E+ R N++ L + V V VKDVND+ P+FKK Y +
Sbjct: 2284 GVIAVIHPLDHETAARYNLTVRATDCLTGAHAEVDVDVAVKDVNDNQPLFKKMAYQVVLS 2343
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY--FIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E V ATD D +N + Y F ++TD F I +G++ LD E
Sbjct: 2344 ETVMIGTPALHVSATDKDSDKNNVIHYQIFSDHNNTDY-FHIDSSSGLILTARMLDHELV 2402
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
K+ V+A DNG D+NDN P F++LL + DEL+
Sbjct: 2403 QKFDFVVIATDNG-FPPLSSEVSVTVMVSDINDNPP---VFNQLLYEAY--VDELAPRG- 2455
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLS 1233
V + A + + ++ + G++ S ++ + ++S
Sbjct: 2456 HFVTCVQASDADSSDYEKLEYSILSGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNIS 2515
Query: 1234 STAILMVTVADVPDEVEMSD--KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMR 1291
+ + + A V +V + PVF YE +++EN +V + T+ R
Sbjct: 2516 VSDGVFTSTAQVHIKVSQGNLYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGR 2575
Query: 1292 YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
ND R F ID NG + DRE V+V Q
Sbjct: 2576 VTYSFVNDVG-RERFSID-ANGQITTAEKLDREDPSNQYVVVSVAAQ 2620
Score = 71.7 bits (168), Expect = 1e-10
Identities = 34/96 (35%), Positives = 57/96 (59%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + VKDVNDH P+F ++ Y +V E+ + +V A D D G+NA++ Y I+ +
Sbjct: 1598 VLIEVKDVNDHVPIFTRSTYEGSVCESSAVGSAVVQVSALDKDKGENADVQYSIESGNKG 1657
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F I P+ G+++++ +L+ + Y+LTV A D G
Sbjct: 1658 NTFHIEPILGIITISHDLNLSSIGHYVLTVRATDKG 1693
Score = 70.9 bits (166), Expect = 2e-10
Identities = 85/310 (27%), Positives = 133/310 (42%), Gaps = 37/310 (11%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLTIPLTV 134
A + V V +EDVNDNVP+F+ PY+ V G F + I ++ L
Sbjct: 2112 ARVLVKVQVEDVNDNVPVFVGLPYYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYLLD 2171
Query: 135 PRG------LT-IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK-PVLLLRK 186
G LT I +AF+ D N V Y+ D G L S+ + P+ ++ K
Sbjct: 2172 DHGHFEINKLTGILSLKKAFESDLSNVEYQMVIYA----RDHGSIPLSSTTEFPITVVNK 2227
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
+ DK F + +++++ P+ I+ G ++ Y ++ G+ F +
Sbjct: 2228 AMP--VFDKPFYSI------SVNEDVAVHTPVLGINATSPKGQSIIYTIVDGDPSLQFDI 2279
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G + + LD H A + L V+A+ A+ V++ + D+NDN P F
Sbjct: 2280 GFDTGVIAVIHPLD----HETAAR-YNLTVRATDCLTGAH-AEVDVDVAVKDVNDNQPLF 2333
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA--FSIDPRSGW-LT 362
+ Y + + E + G L V ATDKD +N YQ+ D F ID SG LT
Sbjct: 2334 KKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQIFSDHNNTDYFHIDSSSGLILT 2393
Query: 363 VRNQTVLDRE 372
R +LD E
Sbjct: 2394 AR---MLDHE 2400
Score = 70.9 bits (166), Expect = 2e-10
Identities = 45/152 (29%), Positives = 71/152 (46%), Gaps = 11/152 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D GV + Y ++ R+ FS+D+ NG + ++LD + N V+ V
Sbjct: 2563 VKATDSDPGVFGRVTYSFVNDVGRERFSIDA-NGQITTAEKLDREDPSNQYV---VVSVA 2618
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + A V++ L+D NDN P F Y S+ ++ GF + QV A+D D G
Sbjct: 2619 AQDAGGHV--SYATVQVSLVDENDNAPHFWATEYRASVRSSVAEGFLLTQVQASDPDAGT 2676
Query: 338 NGEFTYQLDDPK-----GAFSIDPRSGWLTVR 364
N TY + IDP +GW+ +
Sbjct: 2677 NARITYSIYSDSHVPVTDILEIDPDNGWIVTK 2708
Score = 70.1 bits (164), Expect = 4e-10
Identities = 36/110 (32%), Positives = 60/110 (54%)
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ ++L V+AS + L +V +++LD+ND P F Y+++I+E+ P S+ QV
Sbjct: 111 DNYLLTVKASVKGDALLETWTKVSVQVLDMNDLRPLFSPTTYSVTIMESTPLRTSIAQVT 170
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
ATD D G NGEF Y L + F++ P SG + + + +D L +
Sbjct: 171 ATDADIGSNGEFYYFLKNKMDLFAVHPTSGVVLLSGKLNVDERYQHDLEI 220
Score = 70.1 bits (164), Expect = 4e-10
Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 17/218 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E +P+ T I+++ ALD DSG NGQ+RY + S+ + L F I+ + G
Sbjct: 2873 VMEGVPLATRILQVRALDADSGANGQVRYSLGGLI---QSESQQETL--FNTFSIDSQSG 2927
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLND---NISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ +L E S + + A D G + +V V V DVND+ P F + Y +V
Sbjct: 2928 WISTLTNLDHETSSSYVFTVVASDFGEITSFSATATVTVVVTDVNDNPPRFLEQRYFGSV 2987
Query: 1055 EEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDRE 1111
+E V+ +D D D N +++Y I + F + + G L V LDRE
Sbjct: 2988 QEGSPPGEVVAALDTRDNDGSATNRHVSYHITGGNYRGSFALGLVQGEWKLYVKFRLDRE 3047
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
Y + V A D D NDNSP
Sbjct: 3048 ERSLYRINVSASDG----LFVCHTLVHVSVLDANDNSP 3081
Score = 67.3 bits (157), Expect = 3e-09
Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 20/159 (12%)
Query: 239 NDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
N +F ++ G + L K LD L E+ +A V Q + + A V++++
Sbjct: 2801 NQDGVFVVEKDTGLIRLNKPLDHELIKEYYFKATATVQQAKLDSV------ASVDVQVKV 2854
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----------D 346
LD NDN PEF + + +++E +P +LQV A D D G NG+ Y L +
Sbjct: 2855 LDRNDNKPEFVTESFEAAVMEGVPLATRILQVRALDADSGANGQVRYSLGGLIQSESQQE 2914
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
FSID +SGW++ T LD E SS V A +
Sbjct: 2915 TLFNTFSIDSQSGWIS--TLTNLDHETSSSYVFTVVASD 2951
Score = 66.1 bits (154), Expect = 7e-09
Identities = 52/163 (31%), Positives = 85/163 (52%), Gaps = 13/163 (7%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
L+RE +D Y +TV A KG +V++ + D ND P+F TY IME++ +
Sbjct: 105 LNREIQDNYLLTVKASV-KGDALLETWTKVSVQVLDMNDLRPLFSPTTYSVTIMESTPLR 163
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T I + ATDAD G+N F Y L + ++F V +GVV G L+ +++ + L
Sbjct: 164 TSIAQ---VTATDADIGSNGEFYYFLKNK-MDLFAVHPTSGVVLLSG-KLNVDERYQHDL 218
Query: 864 SLVARDTG-------GLSSEAELIIMIGDENDNKPEFNQIEEN 899
++A D G G+SS A+LI+ + N++ P + + +
Sbjct: 219 EILAVDRGMKLYGNNGVSSTAKLIVHVERVNEHAPVISVVNSS 261
Score = 64.9 bits (151), Expect = 2e-08
Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D A L Y+++ + F++DS GS+ LD + + FV
Sbjct: 1841 PLVIKATDADRNENALLVYQIVEDVAKMFFAVDSGTGSIRTIASLDHETLAIFHFHVFVR 1900
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
QL A V I+++D ND+ P+F Y ++ G VLQV ATD D
Sbjct: 1901 DSGRPQLT---ADGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVEVLQVKATDPD 1957
Query: 335 QGENGEFTYQL-DDPKGAFSIDPRSGWLTVR 364
+ + TY L + F+I+P SG + V+
Sbjct: 1958 EDVSRNLTYSLTNGVLEHFAIEPLSGTIVVK 1988
Score = 64.1 bits (149), Expect = 3e-08
Identities = 60/216 (27%), Positives = 97/216 (44%), Gaps = 23/216 (10%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I+V N +A +Q + EN +GT ++++ A D D G+ G++ Y F ++V
Sbjct: 2529 IKVSQGNLYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDV--GR 2586
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLP---PESEFRL-NISALDGGNLNDNISVRVF 1034
+ S DA +G + A L P +++ + +++A D G +V+V
Sbjct: 2587 ERFSIDA------------NGQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVS 2634
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-- 1092
+ D ND+ P F T Y +V + +L +V A+D D G NA +TY I SD+ +P
Sbjct: 2635 LVDENDNAPHFWATEYRASVRSSVAEGFLLTQVQASDPDAGTNARITYSIY-SDSHVPVT 2693
Query: 1093 --FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
EI P G + G V A D G
Sbjct: 2694 DILEIDPDNGWIVTKGAFGHLMNSVLYFFVKAEDGG 2729
Score = 63.3 bits (147), Expect = 5e-08
Identities = 119/473 (25%), Positives = 193/473 (40%), Gaps = 45/473 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V+V V + D NDN PVF LYE + A G + V+A D D + Y
Sbjct: 2419 LSSEVSVTVMVSDINDNPPVF-NQLLYEAYVDELAPRGHFVTCVQASDADSSDYEKLEYS 2477
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVT 556
+ + + F ++ TG V+++ +E ++L + SD S A V
Sbjct: 2478 ILSGNEKLV---FMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDGVFT------STAQVH 2528
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHGY 614
I+V++G P F YE V N +GT V Q++ D+ V+Y ++
Sbjct: 2529 IKVSQGNLY----APVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDV 2584
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRP-MYDFEAVALQENANLSIVTNATVHVVDVNDER 673
F+++ +G IT + L R + Y +VA Q+ V +VD ND
Sbjct: 2585 GRE-RFSIDA-NGQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLVDENDN- 2641
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD----VTDD 729
H + + A G + +S GT N R + D VTD
Sbjct: 2642 -----APHFWATEYRASVRSSVAEGFLLTQVQASDPDAGT-NARITYSIYSDSHVPVTDI 2695
Query: 730 IAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ I D G I T+ V V AE + G + + V +++ + P F
Sbjct: 2696 LEIDPDNGWIVTKGAFGHLMNSVLYFFVKAE-DGGHPARHSLVSVYVHVLSPAASIPSFL 2754
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTG 844
YE + E++ +GT + M + K +A+F K +F V+++TG
Sbjct: 2755 QQHYEFSVAEDTSVGTAVGMLRL-KTPPGYASLSAVFSLVNGAMEKYNQDGVFVVEKDTG 2813
Query: 845 VVKFIGDSLDRE--KKIMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEF 893
+++ + LD E K+ +K + + L S A + + + D NDNKPEF
Sbjct: 2814 LIR-LNKPLDHELIKEYYFKATATVQQAK-LDSVASVDVQVKVLDRNDNKPEF 2864
Score = 62.5 bits (145), Expect = 9e-08
Identities = 93/379 (24%), Positives = 154/379 (40%), Gaps = 44/379 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV--LGKVDATDADFGQNANLTYFIQPSD 1088
V V V D ND+ P+F + Y + E + ++ + +V A D D G N++L+Y I +
Sbjct: 1251 VTVRVLDDNDNKPIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSIADGN 1310
Query: 1089 TDLPFEISPLTGVLSVNGELDRETED-------KYILTVVARDNGXXXXXXXXXXXXXXX 1141
D F I P T VLS T + Y ++ A DNG
Sbjct: 1311 EDAKFFIDPKTAVLSSRKAFAAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLHIEWV 1370
Query: 1142 XDVNDNSPKFYAFDE-LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF 1200
P FD+ + E+D++S V+ + AT+ + G + VF
Sbjct: 1371 RRPPAGPP--LLFDQPFYNFTVMESDKVS--EMVGVVSLRRSAATVWFDITGGNS-ESVF 1425
Query: 1201 ANDTDFIGNGNGLILYSLPQRKNQQ---NLGLPSLSST----AILMVTVADVPDEVEMSD 1253
D G I+ + P QQ NL + + T A + VTV D D +
Sbjct: 1426 HVDKTV-----GTIIIAKPLDAEQQSFYNLTVQATDGTKAAFAQVHVTVLDTND-----N 1475
Query: 1254 KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNG 1313
P+F YE+ + E++ A E++ + + + ++ Y + + D R F I P G
Sbjct: 1476 APIFSQPTYEVTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSIDPSSMRFFHIHPTLG 1535
Query: 1314 TLYLVRSPDREVKDTY--EVIVRAERQKYSRELPHMIYPV---------AEDVLEGMTKY 1362
T++ ++S D E + + V + ++R H V +D K
Sbjct: 1536 TIHTLQSLDHEACALHILTITVSLKLALFARGF-HGYMAVNNKTKTVKKVKDQEFPYRKN 1594
Query: 1363 DVKVVVRIKDVNDNSPKFT 1381
+V++ +KDVND+ P FT
Sbjct: 1595 MARVLIEVKDVNDHVPIFT 1613
Score = 62.5 bits (145), Expect = 9e-08
Identities = 34/118 (28%), Positives = 69/118 (58%), Gaps = 1/118 (0%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ ++ L V+A + ++ L+ A+ V++++ D+NDN+P F Y ++ + G ++ +
Sbjct: 2092 EQESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLPYYAAVQVDAEPGTAIFR 2151
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
VMA D+D+G NG +Y L D G F I+ +G L+++ D ++ +M +YA++
Sbjct: 2152 VMAIDQDKGINGHVSYYLLDDHGHFEINKLTGILSLKKAFESDL-SNVEYQMVIYARD 2208
Score = 61.3 bits (142), Expect = 2e-07
Identities = 51/161 (31%), Positives = 74/161 (45%), Gaps = 13/161 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L Y ++SGN++ +F LD + G + L E N V
Sbjct: 2461 VQASDADSSDYEKLEYSILSGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISV---- 2516
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++ + T+ A+V I++ N P FE + Y + EN G V+QV ATD D G
Sbjct: 2517 ----SDGVFTSTAQVHIKVSQGNLYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGV 2572
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
G TY D + FSID +G +T + LDRE S+
Sbjct: 2573 FGRVTYSFVNDVGRERFSID-ANGQITTAEK--LDREDPSN 2610
Score = 58.8 bits (136), Expect = 1e-06
Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
+A+V++ + D NDN P F Y I + E++P G SVL V A D D GENG TY +
Sbjct: 441 KAQVQVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSISS- 499
Query: 349 KGA--FSIDPRSGWLTVRNQTVLDREAHS 375
GA F I+ SG +T D + S
Sbjct: 500 LGALPFQINQFSGVITTTEPLDFDFSSDS 528
Score = 58.8 bits (136), Expect = 1e-06
Identities = 46/163 (28%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G A ++Y + SGN F ++ + G + + +L+L + +VL V+
Sbjct: 1634 VSALDKDKGENADVQYSIESGNKGNTFHIEPILGIITISHDLNLSS-----IGHYVLTVR 1688
Query: 278 ASQLNNPLKTAQARVEIELLDLNDN-LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ +P + V I + L+DN P+F + Y I EN+ G S++ V A +
Sbjct: 1689 ATDKGSPPLSTTTMVHIS-VTLSDNAAPKFPQEEYLAVITENVAVGTSIITVSAVSQT-- 1745
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSL 377
TY + D G F I+ SG +T R ++ A SL
Sbjct: 1746 ---TLTYDIKQGDADGVFQINQYSGVITTRKALDYEKTASYSL 1785
Score = 57.2 bits (132), Expect = 3e-06
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 8/132 (6%)
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--- 1084
++ V+V V D ND+ P F + V E + +V A DAD G N + Y +
Sbjct: 2847 SVDVQVKVLDRNDNKPEFVTESFEAAVMEGVPLATRILQVRALDADSGANGQVRYSLGGL 2906
Query: 1085 -----QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
Q F I +G +S LD ET Y+ TVVA D G
Sbjct: 2907 IQSESQQETLFNTFSIDSQSGWISTLTNLDHETSSSYVFTVVASDFGEITSFSATATVTV 2966
Query: 1140 XXXDVNDNSPKF 1151
DVNDN P+F
Sbjct: 2967 VVTDVNDNPPRF 2978
Score = 56.4 bits (130), Expect = 6e-06
Identities = 103/495 (20%), Positives = 205/495 (41%), Gaps = 54/495 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ V++ VTL +DN P Y + N VGT I V AV + YD++
Sbjct: 1701 TMVHISVTL---SDNAAPKFPQEEYLAVITENVAVGTSIITVSAVSQTT-----LTYDIK 1752
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ F+IN +G ++ ++ E ++L V+A + S + A++ +
Sbjct: 1753 QGD---ADGVFQINQYSGVITTRKALDYEKTASYSLIVQAVNMAGMASN---ATAIIQL- 1805
Query: 559 VTRGTKGNKPDIPD--FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ N P + G+ E ++V + + + + + L++ E
Sbjct: 1806 --KDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIVE 1863
Query: 617 GVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA----TVHVVDV 669
V FAV+ +G I + L ++ F V ++++ + + T+ V+D
Sbjct: 1864 DVAKMFFAVDSGTGSIRTIASLDHETLAIFHFH-VFVRDSGRPQLTADGPAEVTIQVMDT 1922
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND + ++ ++ ++ AG + Q+ T+ + + N+ + + N V +
Sbjct: 1923 NDSPPQFSQSSYETVL--LRPTYAGVEVLQVKATDPDE---DVSRNLTYSLTN--GVLEH 1975
Query: 730 IAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
AI GTI ++ +R ++ + V + G S + V + + + D+ F
Sbjct: 1976 FAIEPLSGTIVVKQSNFSNERFLFGVRV----SDGQFSSTAL--VNVLVREALDSGLSFS 2029
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y I EN T++ + N + N +YTL G F + +GV++
Sbjct: 2030 QSLYSSTIQENESGITQVAVVNAL-----GNQANEPIVYTLLNGGM-YFKIRPTSGVIQT 2083
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELI--IMIGDENDNKPEFNQIEENSKVRIHR 906
G + DRE++ Y+L + AR A ++ + + D NDN P F + + V++
Sbjct: 2084 TGVAFDREEQESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLPYYAAVQVDA 2143
Query: 907 ETKLNGTAGFTIIEV 921
E GTA F ++ +
Sbjct: 2144 EP---GTAIFRVMAI 2155
Score = 54.8 bits (126), Expect = 2e-05
Identities = 44/167 (26%), Positives = 74/167 (44%), Gaps = 8/167 (4%)
Query: 218 IHAIDQDLGVGATLRYELISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D + Y++ S N+ F +DS +G + + LD H L F V
Sbjct: 2355 VSATDKDSDKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLD----HEL-VQKFDFVV 2409
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P +++ V + + D+NDN P F Y + E P G V V A+D D
Sbjct: 2410 IATDNGFPPLSSEVSVTVMVSDINDNPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSS 2469
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+ + Y + + K F +D +G +T+ ++ E SL + V
Sbjct: 2470 DYEKLEYSILSGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISV 2516
Score = 52.0 bits (119), Expect = 1e-04
Identities = 94/434 (21%), Positives = 174/434 (40%), Gaps = 47/434 (10%)
Query: 989 KRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
K F++++ G V ++ E + LNIS DG V + V N + PVF+
Sbjct: 2484 KLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDGV-FTSTAQVHIKVSQGNLYAPVFE 2542
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ Y V+E + +V ATD+D G +TY F I G ++
Sbjct: 2543 QNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDVGRERFSIDA-NGQITTAE 2601
Query: 1107 ELDRET-EDKYIL-TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
+LDRE ++Y++ +V A+D G D NDN+P F+A + +
Sbjct: 2602 KLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLV---DENDNAPHFWATEYRASVRSSV 2658
Query: 1165 AD-------ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN-GLILY 1216
A+ + S+ + + I Y + + P+ T + ++ ++ + G G ++
Sbjct: 2659 AEGFLLTQVQASDPDAGTNARI-TYSIYSDSHVPV-TDILEIDPDNGWIVTKGAFGHLMN 2716
Query: 1217 S-LPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE--NVNAP 1273
S L ++ G P+ S + V V + P F+ ++YE + E +V
Sbjct: 2717 SVLYFFVKAEDGGHPARHSLVSVYVHVLSPAASI-----PSFLQQHYEFSVAEDTSVGTA 2771
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRR--TFVIDPRNGTLYLVRSPDREVKDTYEV 1331
V ++ L Y + + ++N + FV++ G + L + D E+ Y
Sbjct: 2772 VGMLRLKTPPGYASLSAVFSLVNGAMEKYNQDGVFVVEKDTGLIRLNKPLDHELIKEYYF 2831
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
A V + L+ + DV+ V++ D NDN P+F A+
Sbjct: 2832 KATA--------------TVQQAKLDSVASVDVQ--VKVLDRNDNKPEFV--TESFEAAV 2873
Query: 1392 PTTAPFGYQVMQLK 1405
P +++Q++
Sbjct: 2874 MEGVPLATRILQVR 2887
Score = 48.4 bits (110), Expect = 0.002
Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 17/180 (9%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRK-----LFSLDSVNGSLFLEKELDLDAEHNLQA 269
+ A+D D G +RY L I ++ FS+DS +G ++ +LD E +
Sbjct: 2886 VRALDADSGANGQVRYSLGGLIQSESQQETLFNTFSIDSQSG--WISTLTNLDHE---TS 2940
Query: 270 NTFVLQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+++V V AS +A A V + + D+NDN P F Y S+ E P G V +
Sbjct: 2941 SSYVFTVVASDFGEITSFSATATVTVVVTDVNDNPPRFLEQRYFGSVQEGSPPGEVVAAL 3000
Query: 329 MATDKD-QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D N +Y + + +G+F++ G + + LDRE S R+ V A +
Sbjct: 3001 DTRDNDGSATNRHVSYHITGGNYRGSFALGLVQGEWKLYVKFRLDREERSLYRINVSASD 3060
Score = 45.6 bits (103), Expect = 0.011
Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F +++ G +I+A+ L E + + L + A DG V V V D ND+ P+F +
Sbjct: 1425 FHVDKTVGTIIIAKPLDAEQQSFYNLTVQATDGTKAAF-AQVHVTVLDTNDNAPIFSQPT 1483
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS---DTDLPFEISPLTGVLSVNG 1106
Y V E + +V A D D ++ L+Y +Q S + F I P G +
Sbjct: 1484 YEVTVPEDIPADTEVIQVVAVDRD--RHHQLSYSLQSSIDPSSMRFFHIHPTLGTIHTLQ 1541
Query: 1107 ELDRETEDKYILTV 1120
LD E +ILT+
Sbjct: 1542 SLDHEACALHILTI 1555
Score = 43.6 bits (98), Expect = 0.043
Identities = 19/41 (46%), Positives = 25/41 (60%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G +S+ +SVTV + D+NDN P+F Y VDEL P G
Sbjct: 2415 GFPPLSSEVSVTVMVSDINDNPPVFNQLLYEAYVDELAPRG 2455
Score = 42.7 bits (96), Expect = 0.075
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 8/112 (7%)
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P +F+ Y +ME+ K+ + + ++ ++ F T G + +F VD+
Sbjct: 1378 PLLFDQPFYNFTVMESDKVSEMVGVVSLRRSA-----ATVWFDIT-GGNSESVFHVDKTV 1431
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
G + I LD E++ Y L++ A D G ++ A++ + + D NDN P F+Q
Sbjct: 1432 GTI-IIAKPLDAEQQSFYNLTVQATD-GTKAAFAQVHVTVLDTNDNAPIFSQ 1481
Score = 39.5 bits (88), Expect = 0.69
Identities = 19/41 (46%), Positives = 25/41 (60%)
Query: 74 LNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE 114
+ SA +VTV + DVNDN P FL+ Y +V E +P GE
Sbjct: 2955 ITSFSATATVTVVVTDVNDNPPRFLEQRYFGSVQEGSPPGE 2995
Score = 39.1 bits (87), Expect = 0.92
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 1155 DELLE-WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
D LLE W L ++ + Y TI E+ P+ T++A+V A D D IG+ NG
Sbjct: 124 DALLETWTKVSVQVLDMNDLRPLFSPTTYSVTIMESTPLRTSIAQVTATDAD-IGS-NGE 181
Query: 1214 ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
Y L KN+ +L +S +L+ +V + + + + + R +L V++
Sbjct: 182 FYYFL---KNKMDLFAVHPTSGVVLLSGKLNVDERYQHDLEILAVDRGMKLYGNNGVSST 238
Query: 1274 VELV 1277
+L+
Sbjct: 239 AKLI 242
Score = 37.1 bits (82), Expect = 3.7
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 1401 VMQLKGAIGHHPTASRT-VRADTDELVFFERLSLNGLTSP---QATDSDIGINADIRYQI 1456
++QLK + P + E + LN SP +ATD+D NA + YQI
Sbjct: 1802 IIQLKDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQI 1861
Query: 1457 LNEQAPR-FAIDPVSGTVRVVAALARDAGRVFGF 1489
+ + A FA+D +G++R +A+L + +F F
Sbjct: 1862 VEDVAKMFFAVDSGTGSIRTIASLDHETLAIFHF 1895
>UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51;
Euteleostomi|Rep: Cadherin-23 precursor - Homo sapiens
(Human)
Length = 3354
Score = 161 bits (392), Expect = 1e-37
Identities = 140/469 (29%), Positives = 215/469 (45%), Gaps = 25/469 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +V VT++D NDN P+F + + + T + ++A+D D G NG V Y
Sbjct: 1614 LSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYA 1673
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPANPSERRYSLAVV 555
+ + I + F+I+ + G ++ A+ I GR+ L V A+DQ S R S V
Sbjct: 1674 IVAGN---IVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTV 1730
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGS-NVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+ V N P P P+E G + T + R D+ V Y ++ G
Sbjct: 1731 LVNVN-DINDNVPTFPRDYEGPFEVTEGQPGPRVWTFLAHDR--DSGPNGQVEYSIMDGD 1787
Query: 615 EEGVPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
G F + GV+ V D L R Y+ A LS + V+D+ND
Sbjct: 1788 PLG-EFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDIND 1846
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
VLL + P+ + ENS ++ + H S + F I
Sbjct: 1847 NDPVLL---NLPMNITISENSPVSSF--VAHVLASDADSGCNARLTFNITAGNRERAFFI 1901
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFN--KGVISGAGIYQVTIYIEDENDNPPVFEH 789
A G + +PLDRE+ Y++T+ + N I+ + I++ DENDN P+F
Sbjct: 1902 NATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTK 1961
Query: 790 ATYEGFIMENSKIGTEIKMDN-IIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+TY+ +MENS GT + + N I A DAD+ A+ Y L G +FD++ +TGVV
Sbjct: 1962 STYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTV 2021
Query: 849 -IGDSLDRE--KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
G +DRE + +L L+A D G L+S A L+I I D+NDN+P F+
Sbjct: 2022 RSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFS 2070
Score = 156 bits (378), Expect = 5e-36
Identities = 254/1016 (25%), Positives = 428/1016 (42%), Gaps = 138/1016 (13%)
Query: 439 LMSFVNVEVTLLDANDNNPVFV--PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
L S + V + +LD NDN+PV + P N+ ++ N+ V + + V A D D G N +
Sbjct: 1831 LSSTMLVGIRVLDINDNDPVLLNLPMNI---TISENSPVSSFVAHVLASDADSGCNARLT 1887
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANP--SERRYS 551
+++ + F IN TG V+V P+ R + L + D P NP + R Y
Sbjct: 1888 FNITAGNR---ERAFFINATTGIVTV-NRPLDRERIPEYKLTISVKDNPENPRIARRDYD 1943
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV----GQIRVNDAFEQ--ND 605
L ++ + + P F + Y+ V N GT + G I DA +
Sbjct: 1944 LLLIFLS------DENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAV 1997
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITV----VDDLSRYNRPMYDFEAVALQENANLSIVTN 661
V+Y LL G + G+ F + +GV+TV + D ++ P+ + +A ++ L+ +
Sbjct: 1998 VTYQLL-GAQSGL-FDINSSTGVVTVRSGVIIDREAFSPPILELLLLA-EDIGLLNSTAH 2054
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ ++D ND R + + + H+ EN G ++ Q+ T+ S G V +
Sbjct: 2055 LLITILDDNDNRPTF---SPATLTVHLLENCPPGFSVLQVTATDEDS--GLNGELVYRIE 2109
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
A QD I + +DRE+++ YR+TV+A ++G + +G VTI I+D
Sbjct: 2110 AGAQD-RFLIHLVTGVIRVGNATIDREEQESYRLTVVAT-DRGTVPLSGTAIVTILIDDI 2167
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
ND+ P F + ++E+++ GT I NI T D N Y + G + D
Sbjct: 2168 NDSRPEFLNPIQTVSVLESAEPGTVIA--NI---TAIDHDLNPKLEYHIVG----IVAKD 2218
Query: 841 ENTGVVKFIGDSLD---REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ +V D+ +M K S + R+ L + E+ + + D + PE +
Sbjct: 2219 DTDRLVPNQEDAFAVNINTGSVMVK-SPMNRE---LVATYEVTLSVIDNASDLPERSVSV 2274
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALD 957
N+K+ ++ + T F KP F + + I E GTT+I + A+D
Sbjct: 2275 PNAKLTVNVLDVNDNTPQF-----KP---FGITYY----MERILEGATPGTTLIAVAAVD 2322
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN- 1016
D GLNG + Y +PP + + + G VI R++ E LN
Sbjct: 2323 PDKGLNGLVTYTLLD--LVPPGYVQLE----------DSSAGKVIANRTVDYEEVHWLNF 2370
Query: 1017 -ISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
+ A D G+ + V+++ D+ND+ P+F + Y V E ++ V ATDAD
Sbjct: 2371 TVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDAD 2430
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG---XXXX 1130
G A + Y + D + F I+P TG + V LDRE +D YILT +A+DN
Sbjct: 2431 SGNFALIEYSL--GDGESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNR 2488
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
DVND P+F P+ N + + AT ++
Sbjct: 2489 RENSVQVVIQVLDVNDCRPQF---------SKPQFSTSVYENEPAGTSVITMMATDQDEG 2539
Query: 1191 PIGTTVAKVFANDTD--FIGNGNGLILYSLPQRKNQQ--------NLGLPSLSSTAILMV 1240
P G + + + +GL+ P + ++ + G P L T +L+V
Sbjct: 2540 PNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGTTMLLV 2599
Query: 1241 TVADVPDEVEMSDKPVFI--SRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILN 1296
V DV D ++PVF+ L I E + + + T+ E N +RY L
Sbjct: 2600 EVIDVND-----NRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLK 2654
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVL 1356
F+IDP +G + + DRE + Y +I+ A + PV + +
Sbjct: 2655 TAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVAS---------DLGQPVPYETM 2705
Query: 1357 EGMTKYDVKVVVRIKDVNDNSPKFT----NGNRPLVTAIPTTAPFGYQVMQLKGAI 1408
+ + V ++D++DN P F + + +P +P G V + GA+
Sbjct: 2706 QPLQ-------VALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAV 2754
Score = 152 bits (369), Expect = 6e-35
Identities = 257/1011 (25%), Positives = 406/1011 (40%), Gaps = 135/1011 (13%)
Query: 432 IEYYDEQL---MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
+E Y+ L S V V V + D ND PVF ++ A +GT + V+A D D
Sbjct: 1178 VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRD 1237
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPS 546
G G+V Y + + F+I+ +TG + E + + + V A+DQ A P
Sbjct: 1238 SGDGGLVNYRILSGAE----GKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQ-APPF 1292
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV 606
+ + +T+ + F A YE + N+ +GT + +++ N +
Sbjct: 1293 NQGFCSVYITL------LNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQI 1346
Query: 607 SY--DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
+Y D + F ++ +GVITV + R Y VA + +
Sbjct: 1347 TYRFDAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYI 1406
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQ 723
V+D ND + S + + E+ +GQ T + G+ G V F +A+
Sbjct: 1407 TVLDENDNSPRFDFTSDSAV--SIPED---CPVGQRVATVKAWDPDAGSNGQVVFSLASG 1461
Query: 724 QDV-TDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+I D G +F +PLDRE+ D Y + V+A ++G + + + I D
Sbjct: 1462 NIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVAS-DRGTPPRKKDHILQVTILDI 1520
Query: 781 NDNPPVFEHAT-YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FD 838
NDNPPV E Y + EN GT + ++ATD D G N++ Y + K+M F
Sbjct: 1521 NDNPPVIESPFGYNVSVNENVGGGTAVVQ---VRATDRDIGINSVLSYYITEGNKDMTFR 1577
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQI 896
+D +G + DRE++ Y L D G LS+ + + I DENDN P F Q
Sbjct: 1578 MDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQ- 1636
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
+ +V + T+ TI ALD+D+ GP + I G + N
Sbjct: 1637 -PHYEVLLDEGPDTLNTSLITI--------QALDLDE-GPNGTVTYAIVAGNIV---NTF 1683
Query: 957 DLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN 1016
+D + G I +A L+ Y + + R+ ++ A P RL
Sbjct: 1684 RIDRHM-GVI--------------TAAKELD---YEISHGRYTLIVTATDQCPILSHRLT 1725
Query: 1017 ISALDGGNLND-NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
+ N+ND N +V F +D F V E Q RV + A D D G
Sbjct: 1726 STTTVLVNVNDINDNVPTFPRDYEG----------PFEVTEGQPGPRVWTFL-AHDRDSG 1774
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSV--NGELDRETEDKYILTVVARDNGXXXXXXX 1133
N + Y I D F ISP+ GVL V + ELDRET Y LT+ ARD G
Sbjct: 1775 PNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRG-MPPLSS 1833
Query: 1134 XXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG 1193
D+NDN P ++ +P+ TI EN+P+
Sbjct: 1834 TMLVGIRVLDINDNDP-------------------------VLLNLPM-NITISENSPVS 1867
Query: 1194 TTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD---EVE 1250
+ VA V A+D D N + R+ + + T + +P+ +
Sbjct: 1868 SFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTIS 1927
Query: 1251 MSDKPV---FISRYYELEI----EENVNAPVELVSLNLTEHYENFK--MRYYILN----- 1296
+ D P R Y+L + +EN N P+ S E EN +LN
Sbjct: 1928 VKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILA 1987
Query: 1297 -ENDTDIRR--TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
+ D DI T+ + L+ + S V VI+ +R+ +S + ++ +AE
Sbjct: 1988 LDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVII--DREAFSPPILELLL-LAE 2044
Query: 1354 DVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
D+ G+ +++ I D NDN P F+ L + P G+ V+Q+
Sbjct: 2045 DI--GLLNSTAHLLITILDDNDNRPTFSPAT--LTVHLLENCPPGFSVLQV 2091
Score = 143 bits (346), Expect = 4e-32
Identities = 215/799 (26%), Positives = 316/799 (39%), Gaps = 125/799 (15%)
Query: 403 WRRQPLETNAPLEKTT-YVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVP 461
W RQPL+ E T + D G T VN++V D NDN P F
Sbjct: 88 WLRQPLDRETKSEFTVEFSVSDHQGVITRK-----------VNIQVG--DVNDNAPTF-H 133
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS 521
+ Y + N VGT I V A DPDLG G VLY Q S F I+ G V+
Sbjct: 134 NQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF-----FAIDSARGIVT 188
Query: 522 VAESPILEGRHA--LFVEASDQP-ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPY 578
V E A L V A+DQ P +LA++ +V + P F+ PY
Sbjct: 189 VIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDV-------QDMDPIFINLPY 241
Query: 579 EFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLS 636
+ + GT+V I D + Y ++ G + FA++ SGV+T+ L
Sbjct: 242 STNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSI-FALDYISGVLTLNGLLD 300
Query: 637 RYNRPMYDFEAVALQENANLS---------IVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
R N P+Y + + L+ + T + V+D+ND +S I
Sbjct: 301 REN-PLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITE 359
Query: 688 VKENSAGAAIG-QIFH-------TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+ + + Q+ +M +Y G + F+I+ + D I
Sbjct: 360 LAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIIS-----PTSVQGKADIRIR 414
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
PLD E D Y + A N+ V G +V I + +ENDN P+F Y + EN
Sbjct: 415 VAIPLDYETVDRYDFDLFA--NESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYEN 472
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+GT + + ATD D GT FGE V F D DR
Sbjct: 473 VTVGTSVLT---VLATDNDAGT--------FGE------------VSYFFSDDPDR---- 505
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTII 919
+ L +DTG LI++I + ++ I+ + I R+ T G I
Sbjct: 506 -FSLD---KDTG-------LIMLIA-----RLDYELIQRFTLTIIARDGGGEETTGRVRI 549
Query: 920 EVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
V N + + + EN P T +++L A D DS N QI Y S
Sbjct: 550 NVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITY----------S 599
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESE------FRLNISALDGGN--LNDNISV 1031
+SA A YF I+ G+ +++ S P + E L + A+D GN LN + V
Sbjct: 600 IVSASAFG--SYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPV 657
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
+ V D ND+ P F K Y +V E + ++ATD D + I +
Sbjct: 658 TIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST 717
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPK 1150
F I+ +G ++ LDRET+ +YIL V A D G D+NDN P
Sbjct: 718 QFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPT 777
Query: 1151 FY---AFDELLEWKHPEAD 1166
+ + L+E P++D
Sbjct: 778 WKDAPYYINLVEMTPPDSD 796
Score = 118 bits (285), Expect = 9e-25
Identities = 134/498 (26%), Positives = 206/498 (41%), Gaps = 48/498 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q V +TLLD NDN+P + + Y ++ + + V AVDPDLG+NG ++Y
Sbjct: 757 QKTGIATVNITLLDINDNHPTWKDAPYY-INLVEMTPPDSDVTTVVAVDPDLGENGTLVY 815
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVA------ESP---ILEGRHALFVEASDQPANPSER 548
+Q + + +N TG + E+P E + V +D P +
Sbjct: 816 SIQPPNKF-----YSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTD-CGRPPLK 869
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
S A V + + N D P F P+ V + G S+ Q+ D E V
Sbjct: 870 ATSSATVFVNL---LDLNDND-PTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLV 925
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVH 665
SY + G + F + SGV+ +L R Y VA S + T+H
Sbjct: 926 SYRMPVGMPR-MDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIH 984
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVR---FLIA 721
V+DVNDE P +++V S + + F + N G N F+
Sbjct: 985 VLDVNDETPTFF-----PAVYNV---SVSEDVPREFRVVWLNCTDNDVGLNAELSYFITG 1036
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS--GAGIYQVTIYIED 779
D + D + T LDRE Y M ++ + G + G V + + D
Sbjct: 1037 GNVDGKFSVGY-RDAVVRTVVGLDRETTAAY-MLILEAIDNGPVGKRHTGTATVFVTVLD 1094
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY-TLFGEGKEMFD 838
NDN P+F ++YE + E+ G I +KATDADEG Y L G F
Sbjct: 1095 VNDNRPIFLQSSYEASVPEDIPEGHSILQ---LKATDADEGEFGRVWYRILHGNHGNNFR 1151
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVA--RDTGGLSSEAELIIMIGDENDNKPEFNQI 896
+ + G++ LDRE+ + L + A D G + S +I+ + D ND P F Q
Sbjct: 1152 IHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQ- 1210
Query: 897 EENSKVRIHRETKLNGTA 914
++ S++ + RET GT+
Sbjct: 1211 QQYSRLGL-RETAGIGTS 1227
Score = 107 bits (257), Expect = 2e-21
Identities = 125/441 (28%), Positives = 195/441 (44%), Gaps = 37/441 (8%)
Query: 443 VNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ V + ++D NDNNP+F PS Y+ ++ + VGT+I V A D D G ++ Y L
Sbjct: 2386 IPVYLEIVDINDNNPIFDQPS--YQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGD 2443
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPAN-PSERRYSLAVVTIE 558
S F INP TG + V S E + + L A D P + S RR + V I+
Sbjct: 2444 GE-----SKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQ 2498
Query: 559 VTRGTKGNKPDI--PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
V +P P F + YE N GTSV + D E +++Y L
Sbjct: 2499 VL-DVNDCRPQFSKPQFSTSVYE-----NEPAGTSVITMMATDQDEGPNGELTYSLEGPG 2552
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDER 673
E F V+ SG++T L Y + + VA L T V V+DVND R
Sbjct: 2553 VEA--FHVDMDSGLVTTQRPLQSYEK--FSLTVVATDGGEPPLWGTTMLLVEVIDVNDNR 2608
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL-IANQQDVTDDIAI 732
V ++ + I+ +E + + +++ T+ NG FL A +D I
Sbjct: 2609 PVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGL-NGAVRYSFLKTAGNRDWEFFIID 2667
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH--- 789
G I T + LDRE + VY + ++A + + + + +ED +DN P+F
Sbjct: 2668 PISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPK 2727
Query: 790 --ATYEGF-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
Y+ + E+S GT + N+ A DADEG NA+ Y + +E + G +
Sbjct: 2728 GSPQYQLLTVPEHSPRGTLV--GNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCL 2785
Query: 847 KFIGDSLDREKKIMYKLSLVA 867
+ D LDRE++ ++ + A
Sbjct: 2786 LVLRD-LDREREAIFSFIVKA 2805
Score = 105 bits (252), Expect = 9e-21
Identities = 122/457 (26%), Positives = 197/457 (43%), Gaps = 29/457 (6%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +LD ND P F P+ +Y S+ + + + D D+G N + Y + +
Sbjct: 983 IHVLDVNDETPTFFPA-VYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFI---TGGN 1038
Query: 507 ITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ F + V E + L +EA D P +R++
Sbjct: 1039 VDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDN--GPVGKRHTGTATVFVTVLDVN 1096
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYEEGVPFAV 622
N+P F+ + YE V ++ G S+ Q++ DA E V Y +LHG G F +
Sbjct: 1097 DNRPI---FLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHG-NHGNNFRI 1152
Query: 623 EERSGVITVVD---DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
+G++ D R + + EA S V V+V D+NDE V +
Sbjct: 1153 HVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSV-RVIVYVEDINDEAPVFTQQ 1211
Query: 680 AHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+S + ++E + G ++ + T+ S G+G G V + I + + +I G I
Sbjct: 1212 QYSRL--GLRETAGIGTSVIVVQATDRDS--GDG-GLVNYRILSGAEGKFEID-ESTGLI 1265
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LD E + Y M V A ++ G V I + +E D F +A+YE I+E
Sbjct: 1266 ITVNYLDYETKTSYMMNVSAT-DQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILE 1324
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
N +GTEI + ++ T YT + K +F +D TGV+ G +DREK
Sbjct: 1325 NLALGTEIVRVQAYSIDNLNQITYRFDAYT-STQAKALFKIDAITGVITVQG-LVDREKG 1382
Query: 859 IMYKLSLVARDTG-GLSSEAELIIMIGDENDNKPEFN 894
Y L++VA D G + S ++ I + DENDN P F+
Sbjct: 1383 DFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFD 1419
Score = 105 bits (251), Expect = 1e-20
Identities = 118/439 (26%), Positives = 185/439 (42%), Gaps = 33/439 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
S V V LLD NDN+P F NL + + G I +V A+D D G NG+V Y
Sbjct: 872 SSATVFVNLLDLNDNDPTF--QNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSY-- 927
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
R F IN ++G V E + L V ASD +L + +
Sbjct: 928 -RMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVL 986
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYE 615
+V T P F A Y V +V V + ND ++SY + G
Sbjct: 987 DVNDET-------PTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNV 1039
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHV--VDVNDE 672
+G F+V R V+ V L R Y A+ ATV V +DVND
Sbjct: 1040 DG-KFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDN 1098
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
R + L+ ++ + ++ G +I Q+ T+ G V + I + +
Sbjct: 1099 RPIFLQSSYEASV--PEDIPEGHSILQLKATDADE---GEFGRVWYRILHGNHGNNFRIH 1153
Query: 733 AEDGTIFT-QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+G + +PLDRE+ + + ++ +N + +V +Y+ED ND PVF
Sbjct: 1154 VSNGLLMRGPRPLDRERNSSH-VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQ 1212
Query: 792 YEGF-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y + E + IGT + +++ATD D G L Y + + F++DE+TG++ +
Sbjct: 1213 YSRLGLRETAGIGTSVI---VVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITV- 1268
Query: 851 DSLDREKKIMYKLSLVARD 869
+ LD E K Y +++ A D
Sbjct: 1269 NYLDYETKTSYMMNVSATD 1287
Score = 104 bits (249), Expect = 2e-20
Identities = 91/334 (27%), Positives = 155/334 (46%), Gaps = 24/334 (7%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPT-GEKAFIFLIAP-IGPSL 128
G G NQ + +V + + D+NDN P + D PY++ + E+TP + + + P +G +
Sbjct: 752 GVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENG 811
Query: 129 TIPLTVPRGLTIFK------DIRA----FDRDKPNTPNSDVHYSIV-SGNDDGHFALESS 177
T+ ++ + IR DR+ P+ +++ IV S D G L+++
Sbjct: 812 TLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKAT 871
Query: 178 HKPVLLLRKVLDYDAGDKEFQ-LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
+ + +LD + D FQ L +A + + AID D G+ + Y +
Sbjct: 872 SSATVFVN-LLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMP 930
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
G R F ++S +G + ELD + Q L+V AS P K++ + + I +
Sbjct: 931 VGMPRMDFLINSSSGVVVTTTELDRERIAEYQ-----LRVVASDAGTPTKSSTSTLTIHV 985
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
LD+ND P F YN+S+ E++P F V+ + TD D G N E +Y + + G FS+
Sbjct: 986 LDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSV 1045
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
R VR LDRE ++ + + A + P
Sbjct: 1046 GYRDA--VVRTVVGLDRETTAAYMLILEAIDNGP 1077
Score = 104 bits (249), Expect = 2e-20
Identities = 106/424 (25%), Positives = 180/424 (42%), Gaps = 22/424 (5%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G+ +S+ + V + + D+NDN P+ L+ P ++T+ E +P L A G + +
Sbjct: 1827 GMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARL 1886
Query: 131 PLTVPRG-------LTIFKDIRAFDR--DKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
+ G + I +R D+ P + S+ ++ A +
Sbjct: 1887 TFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLL 1946
Query: 182 LLLRKVLDYDA--GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
+ L D +Q +M + + PI A+D D + A + Y+L+ G
Sbjct: 1947 IFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLL-GA 2005
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
LF ++S G + + + +D E L + A + L + A + I +LD
Sbjct: 2006 QSGLFDINSSTGVVTVRSGVIIDREA-FSPPILELLLLAEDIG--LLNSTAHLLITILDD 2062
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGAFSIDPRS 358
NDN P F + ++EN P GFSVLQV ATD+D G NGE Y+++ + F I +
Sbjct: 2063 NDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHLVT 2122
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKETNP-SVVGTFADSQRIAKWRRQPLETNAPLEKT 417
G + V N T+ DRE S R+ V A + + GT + I E P++
Sbjct: 2123 GVIRVGNATI-DREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTV 2181
Query: 418 TYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT 477
+ + + GT NI D L + + + A D+ VP+ F++ N G+
Sbjct: 2182 SVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAV--NINTGS 2239
Query: 478 VIGK 481
V+ K
Sbjct: 2240 VMVK 2243
Score = 101 bits (242), Expect = 2e-19
Identities = 135/518 (26%), Positives = 204/518 (39%), Gaps = 65/518 (12%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
LN T TI EV +N + + ENI G T++ LNA DLD Y
Sbjct: 651 LNSTVPVTI-EVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSR----EYG 705
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG---N 1024
S +Y +LE F IN R G + L E SE+ L + A+DGG N
Sbjct: 706 QESIIY---------SLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHN 756
Query: 1025 LNDNI-SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
I +V + + D+ND+ P +K Y N+ E + V A D D G+N L Y
Sbjct: 757 QKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYS 816
Query: 1084 IQPSDTDLPFEISPLTG-VLSVNGELDRETEDKY------ILTVVARDNGX-XXXXXXXX 1135
IQP + + ++ TG + + + LDRE D + + V D G
Sbjct: 817 IQPPNKF--YSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSA 874
Query: 1136 XXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTT 1195
D+NDN P F + E +S + ++ + + P+G
Sbjct: 875 TVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 934
Query: 1196 VAKVFANDTDFIG------NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV 1249
N + + + + Y L R + G P+ SST+ L + V DV DE
Sbjct: 935 RMDFLINSSSGVVVTTTELDRERIAEYQL--RVVASDAGTPTKSSTSTLTIHVLDVNDET 992
Query: 1250 EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFV 1307
P F Y + + E+V +V LN T++ N ++ Y+I N + F
Sbjct: 993 -----PTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGN---VDGKFS 1044
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV 1367
+ R+ + V DRE Y +I+ A PV + T V
Sbjct: 1045 VGYRDAVVRTVVGLDRETTAAYMLILEAIDNG----------PVGKRHTGTAT-----VF 1089
Query: 1368 VRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
V + DVNDN P F + ++P P G+ ++QLK
Sbjct: 1090 VTVLDVNDNRPIFLQSS--YEASVPEDIPEGHSILQLK 1125
Score = 101 bits (241), Expect = 2e-19
Identities = 120/487 (24%), Positives = 199/487 (40%), Gaps = 44/487 (9%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T T+ +L S V V + D NDN P F F + + + G + A D
Sbjct: 1712 TATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEV-TEGQPGPRVWTFLAHD 1770
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVE----ASDQP 542
D G NG V Y + L F I+P G + V + L+ F A D+
Sbjct: 1771 RDSGPNGQVEYSIMDGDPL---GEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRG 1827
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
P + + +++ N D P + P + N + + V + +DA
Sbjct: 1828 MPPLSSTMLVGIRVLDI------NDND-PVLLNLPMNITISENSPVSSFVAHVLASDADS 1880
Query: 603 QND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT 660
+ +++++ G E F + +G++TV L R P Y N I
Sbjct: 1881 GCNARLTFNITAGNRERA-FFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1939
Query: 661 N----ATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAI----GQIFHTNMSS-IYG 710
+ + D ND + K + V ENS AG + G I + IY
Sbjct: 1940 RDYDLLLIFLSDENDNHPLFTKSTYQA---EVMENSPAGTPLTVLNGPILALDADQDIYA 1996
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE--KRDVYRMTVIAEFNKGVISGA 768
T + + D+ + T+ + +DRE + + ++AE + G+++
Sbjct: 1997 VVTYQLLGAQSGLFDINSSTGVV---TVRSGVIIDREAFSPPILELLLLAE-DIGLLNST 2052
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+TI D+NDN P F AT ++EN G + + ATD D G N +Y
Sbjct: 2053 AHLLITIL--DDNDNRPTFSPATLTVHLLENCPPGFSVLQ---VTATDEDSGLNGELVYR 2107
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
+ ++ F + TGV++ ++DRE++ Y+L++VA D G LS A + I+I D
Sbjct: 2108 IEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDI 2167
Query: 887 NDNKPEF 893
ND++PEF
Sbjct: 2168 NDSRPEF 2174
Score = 98.7 bits (235), Expect = 1e-18
Identities = 176/726 (24%), Positives = 285/726 (39%), Gaps = 85/726 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK-VKAVDPD--LGQNGMV-LYDLQRT 502
+ ++D NDN P F S Y ++ A+VG + ++ VD D LG N M +Y +
Sbjct: 336 ILVIDINDNAPEFNSSE-YSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNN 394
Query: 503 SNLTITSPFKINPNTGT-VSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S+ I SP + + VA E + + P Y+ +T+
Sbjct: 395 SHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINEN 454
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP 619
+ P F Y + NV +GTSV + NDA +VSY +
Sbjct: 455 DNR------PIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDR--- 505
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F++++ +G+I ++ L + +A ++ ++V+DVND K
Sbjct: 506 FSLDKDTGLIMLIARLDYELIQRFTLTIIA-RDGGGEETTGRVRINVLDVNDNVPTFQKD 564
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD--DIAIAED-G 736
A+ + ++EN ++ Q+ + + + I + DI++ E G
Sbjct: 565 AY---VGALRENEP--SVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYG 619
Query: 737 TIFTQKPLDREK--RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
I +PLD E+ + +TV+A + G VTI + DENDNPP F Y
Sbjct: 620 VISVSRPLDYEQISNGLIYLTVMA-MDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFV 678
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
++EN G + N + E +Y+L EG F ++ +G + LD
Sbjct: 679 SVVENIMAGATVLFLNATDLDRSREYGQESIIYSL--EGSTQFRINARSGEITTTS-LLD 735
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
RE K SE LI+ D + N K I T
Sbjct: 736 RETK----------------SEYILIVRAVDGG--------VGHNQKTGI-------ATV 764
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
T++++ + D P ++ + E P + + + A+D D G NG + Y
Sbjct: 765 NITLLDINDNHPTWKDA----PYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQ-- 818
Query: 974 VYIPPSKL-SADALEVKRYFVINERHGHVIVARSLPPESEF--RLNISALDGGN--LNDN 1028
PP+K S ++ K I H + P E+E ++ +S D G L
Sbjct: 819 ---PPNKFYSLNSTTGK----IRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKAT 871
Query: 1029 ISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
S VFV D+ND+ P F+ + V E + +V A D D G N ++Y +
Sbjct: 872 SSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPV 931
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ F I+ +GV+ ELDRE +Y L VVA D G DVND
Sbjct: 932 GMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAG-TPTKSSTSTLTIHVLDVND 990
Query: 1147 NSPKFY 1152
+P F+
Sbjct: 991 ETPTFF 996
Score = 97.1 bits (231), Expect = 3e-18
Identities = 117/419 (27%), Positives = 173/419 (41%), Gaps = 53/419 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E IP G +I ++ A+DLD GLNG + Y V +P + F+IN G V
Sbjct: 901 EGIPAGVSIYQVVAIDLDEGLNGLVSYRM--PVGMP-----------RMDFLINSSSGVV 947
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ L E +E++L + A D G + ++ + V DVND P F YN +V E
Sbjct: 948 VTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSED 1007
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ ++ TD D G NA L+YFI + D F + V+ LDRET Y+
Sbjct: 1008 VPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYM 1067
Query: 1118 LTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L + A DNG DVNDN P F E PE D H S+
Sbjct: 1068 LILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIF--LQSSYEASVPE-DIPEGH---SI 1121
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFAND--TDF-IGNGNGLILYS---LPQRKNQQ----- 1225
+ + KAT + G ++ + +F I NGL++ L + +N
Sbjct: 1122 LQL---KATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIV 1178
Query: 1226 ---NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY-ELEIEENVNAPVELVSLNL 1281
N L + S+ ++V V D+ DE PVF + Y L + E ++ +
Sbjct: 1179 EAYNHDLGPMRSSVRVIVYVEDINDEA-----PVFTQQQYSRLGLRETAGIGTSVIVVQA 1233
Query: 1282 TEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
T+ + + Y IL + F ID G + V D E K +Y + V A Q
Sbjct: 1234 TDRDSGDGGLVNYRIL----SGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQ 1288
Score = 95.5 bits (227), Expect = 1e-17
Identities = 131/529 (24%), Positives = 222/529 (41%), Gaps = 58/529 (10%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ + V++TL++ NDN P+F LY S+ N VGT + V A D D G G V Y
Sbjct: 441 VGYAKVKITLINENDNRPIF-SQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFF 499
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
+ F ++ +TG + + E R L + A D + R + V+ +
Sbjct: 500 SDDPD-----RFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVLDV 554
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYE 615
++P F Y + N T + ++R D+ N ++Y ++
Sbjct: 555 ---------NDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASA 605
Query: 616 EGVPFAVE--ERSGVITVVD--DLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVN 670
G F + E GVI+V D + + + +A+ N L+ T+ V D N
Sbjct: 606 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D K A+ + V+ AGA + + T++ G ++ I + + T
Sbjct: 666 DNPPTFSKPAY--FVSVVENIMAGATVLFLNATDLDRSREYGQESI---IYSLEGSTQFR 720
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
A G I T LDRE + Y + V A + G GI V I + D NDN P ++
Sbjct: 721 INARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKD 780
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
A Y ++E + +++ + A D D G N +Y++ K + ++ TG ++
Sbjct: 781 APYYINLVEMTPPDSDV---TTVVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTT 836
Query: 850 GDSLDREK------KIMYKLSLVARDTG----GLSSEAELIIMIGDENDNKPEFNQIEEN 899
LDRE ++M K+ + D G +S A + + + D NDN P F +
Sbjct: 837 HAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFV 896
Query: 900 SKVRIHRETKLNG-TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIG 947
++V L G AG +I +V A+D+D+ G L+ +P+G
Sbjct: 897 AEV-------LEGIPAGVSIYQV-----VAIDLDE-GLNGLVSYRMPVG 932
Score = 93.9 bits (223), Expect = 3e-17
Identities = 91/329 (27%), Positives = 146/329 (44%), Gaps = 23/329 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V + + DVNDN P F + PY V + E TP G IF++ P L +V
Sbjct: 118 VNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTP--IFIVNATDPDLGAGGSVLYSFQPPS 175
Query: 143 DIRAFDRDKPN-TPNSDVHYSIVSGNDDGHFALESSH-KPVLLLRK--VLDYDAGDKEFQ 198
A D + T ++ Y A + +P+ L ++ D D +
Sbjct: 176 QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPI 235
Query: 199 LVIMASGKRIHKEI---LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL 255
+ + I++ I AIDQD G + Y ++SGN +F+LD ++G L L
Sbjct: 236 FINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTL 295
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV----EIELLDLNDNLPEFEVDFY 311
LD E+ L ++ F+L V+ ++LN+ + A V I ++D+NDN PEF Y
Sbjct: 296 NGL--LDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEY 353
Query: 312 NISIVENLPNGFSV---LQVMATDKDQGENGEF-TYQLDDPKGAFSIDPRS----GWLTV 363
+++I E GF++ +QV+ D++ G N F Y + + F I P S + +
Sbjct: 354 SVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRI 413
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVG 392
R LD E ++A E+ P VG
Sbjct: 414 RVAIPLDYETVDRYDFDLFANESVPDHVG 442
Score = 87.4 bits (207), Expect = 3e-15
Identities = 93/351 (26%), Positives = 154/351 (43%), Gaps = 24/351 (6%)
Query: 85 VYIEDVNDNVPIFLDTP--YHVTVDELTPTGEKAFIFLIAP---IGPSLTIPLTVPRG-- 137
V I D+NDN P+ +++P Y+V+V+E G A + + A IG + + + G
Sbjct: 1515 VTILDINDNPPV-IESPFGYNVSVNE-NVGGGTAVVQVRATDRDIGINSVLSYYITEGNK 1572
Query: 138 -LTIFKD-IRAFDRDKPNTPNSD---VHYSIVSGNDDGHFALESS-HKPVLLLRKVLDYD 191
+T D I +P P+ + ++ + + D+G L ++ H V ++ + +
Sbjct: 1573 DMTFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAP 1632
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
+ V++ G L I A+D D G T+ Y +++GN F +D G
Sbjct: 1633 MFQQPHYEVLLDEGPDTLNTSLIT--IQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMG 1690
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ KELD + H Q L++ L T+ V + + D+NDN+P F D+
Sbjct: 1691 VITAAKELDYEISHGRYTLIVTATDQCPILSHRL-TSTTTVLVNVNDINDNVPTFPRDYE 1749
Query: 312 N-ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
+ E P G V +A D+D G NG+ Y + DP G F I P G L VR
Sbjct: 1750 GPFEVTEGQP-GPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVE 1808
Query: 369 LDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWR-RQPLETNAPLEKT 417
LDRE + + + A++ P + T R+ P+ N P+ T
Sbjct: 1809 LDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNIT 1859
Score = 87.0 bits (206), Expect = 3e-15
Identities = 134/517 (25%), Positives = 211/517 (40%), Gaps = 72/517 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ P+G + + A D D+G NGQ+ V+ S A A E+ N+ G
Sbjct: 1428 IPEDCPVGQRVATVKAWDPDAGSNGQV-------VFSLASGNIAGAFEI---VTTNDSIG 1477
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTW-YNFN 1053
V VAR L E + L + A D G D+I ++V + D+ND+ PV + + YN +
Sbjct: 1478 EVFVARPLDREELDHYILQVVASDRGTPPRKKDHI-LQVTILDINDNPPVIESPFGYNVS 1536
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN-GELDRET 1112
V E + +V ATD D G N+ L+Y+I + D+ F + ++G ++ DRE
Sbjct: 1537 VNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMTFRMDRISGEIATRPAPPDRER 1596
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADELSN 1170
+ Y L D G D NDN+P F ++ LL+ + P+ S
Sbjct: 1597 QSFYHLVATVEDEG-TPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLD-EGPDTLNTSL 1654
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTV----------AKVFANDTDF-IGNGNGLILYSLP 1219
+++ + T+ G V A + D+ I +G ++ +
Sbjct: 1655 ITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVT-- 1712
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+Q + L+ST ++V V D+ D V P F R YE E P V
Sbjct: 1713 -ATDQCPILSHRLTSTTTVLVNVNDINDNV-----PTF-PRDYEGPFEVTEGQPGPRVWT 1765
Query: 1280 NLTEHYE---NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP--DREVKDTYEVIVR 1334
L + N ++ Y I+ D D FVI P G L + + DRE Y + +
Sbjct: 1766 FLAHDRDSGPNGQVEYSIM---DGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTIC 1822
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTT 1394
A R +P P++ +L G +R+ D+NDN P N P+ I
Sbjct: 1823 AR----DRGMP----PLSSTMLVG---------IRVLDINDNDPVLL--NLPMNITISEN 1863
Query: 1395 AP---FGYQVMQLKGAIGHHPTASRTVRADTDELVFF 1428
+P F V+ G + + + A E FF
Sbjct: 1864 SPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFF 1900
Score = 81.4 bits (192), Expect = 2e-13
Identities = 113/492 (22%), Positives = 204/492 (41%), Gaps = 54/492 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + +LD ND P F + S+ N GT + + A D D G NG + Y L+
Sbjct: 2493 VQVVIQVLDVNDCRPQFSKPQ-FSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGP 2551
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F ++ ++G V+ + +L V A+D P L V I+V
Sbjct: 2552 G----VEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVN-- 2605
Query: 563 TKGNKPDIPDFMGAPYE--FWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH--GYEE 616
N+P F+ P + + + ++V ++ D E V Y L G +
Sbjct: 2606 --DNRPV---FVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRD 2660
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERG 674
F ++ SG+I L R ++ +Y VA + T + V D++D
Sbjct: 2661 WEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEP 2720
Query: 675 VLL---KGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ + KG+ + V E+S G +G + + + G F+ A ++ +
Sbjct: 2721 LFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGA-VDADEGPNAIVYYFIAAGNEE--KNF 2777
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKG------------VISGAGIYQVTIYIE 778
+ DG + + LDRE+ ++ V A N+ +++ + +V + +E
Sbjct: 2778 HLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLE 2837
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEM 836
D ND PP F A Y + ++K+G+E+ + A DAD G N+L Y++ + +
Sbjct: 2838 DINDQPPRFTKAEYTAGVATDAKVGSELIQ---VLALDADIGNNSLVFYSILAIHYFRAL 2894
Query: 837 FDVDENTGVVKFIG--DSLDREKKIM-------YKLSLVARDTGGLSSEAEL-IIMIGDE 886
+ E+ G V +G D + R + + + +VARD G + A + I ++ D+
Sbjct: 2895 ANDSEDVGQVFTMGSMDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDD 2954
Query: 887 NDNKPEFNQIEE 898
K N+I +
Sbjct: 2955 QRVKIVINEIPD 2966
Score = 80.6 bits (190), Expect = 3e-13
Identities = 47/148 (31%), Positives = 78/148 (52%), Gaps = 4/148 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y L G + F+++ G +++ LD + + +
Sbjct: 2424 VTATDADSGNFALIEYSLGDGESK--FAINPTTGDIYVLSSLDREKKDHYILTALAKDNP 2481
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+N + + +V I++LD+ND P+F ++ S+ EN P G SV+ +MATD+D+G
Sbjct: 2482 GDVASNRRENS-VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGP 2540
Query: 338 NGEFTYQLDDP-KGAFSIDPRSGWLTVR 364
NGE TY L+ P AF +D SG +T +
Sbjct: 2541 NGELTYSLEGPGVEAFHVDMDSGLVTTQ 2568
Score = 80.2 bits (189), Expect = 4e-13
Identities = 128/492 (26%), Positives = 206/492 (41%), Gaps = 65/492 (13%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++P+GT I+ + A D DSG I Y E K F IN G +
Sbjct: 2413 EDVPVGTIILTVTATDADSGNFALIEYSLGDG-------------ESK--FAINPTTGDI 2457
Query: 1002 IVARSLPPESEFRLNISALDGGNLND--------NISVRVFVKDVNDHFPVFKKTWYNFN 1053
V SL E + ++AL N D ++ V + V DVND P F K ++ +
Sbjct: 2458 YVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTS 2517
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E + + + ATD D G N LTY ++ + F + +G+++ L ++
Sbjct: 2518 VYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEA-FHVDMDSGLVTTQRPL--QSY 2574
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+K+ LTVVA D G DVNDN P F E L ++ +
Sbjct: 2575 EKFSLTVVATDGGEPPLWGTTMLLVEVI-DVNDNRPVFVRPPNGTILHIREEIPLRSNVY 2633
Query: 1174 ESVMMIPVYKATIEE--NAPIGTTVAKVFAN-DTDF--IGNGNGLILYSLPQRKNQQ--- 1225
E VY +E N + + K N D +F I +GLI + + Q
Sbjct: 2634 E------VYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVY 2687
Query: 1226 -------NLGLPSLSSTAI-LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+LG P T L V + D+ D + +P S Y+L + ++P +
Sbjct: 2688 SLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQL-LTVPEHSPRGTL 2746
Query: 1278 SLNLT-----EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
N+T + N + Y+I N+ + F + P +G L ++R DRE + + I
Sbjct: 2747 VGNVTGAVDADEGPNAIVYYFIAAGNE---EKNFHLQP-DGCLLVLRDLDREREAIFSFI 2802
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
V+A + S P P D++ +T +V+VV ++D+ND P+FT +
Sbjct: 2803 VKASSNR-SWTPPRGPSPTL-DLVADLTLQEVRVV--LEDINDQPPRFTKAE--YTAGVA 2856
Query: 1393 TTAPFGYQVMQL 1404
T A G +++Q+
Sbjct: 2857 TDAKVGSELIQV 2868
Score = 78.2 bits (184), Expect = 2e-12
Identities = 56/175 (32%), Positives = 88/175 (50%), Gaps = 12/175 (6%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G ++ ++PLDRE + + + ++GVI+ +V I + D NDN P F + Y
Sbjct: 83 DTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITR----KVNIQVGDVNDNAPTFHNQPYS 138
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I EN+ +GT I I+ ATD D G +Y+ F + F +D G+V I + L
Sbjct: 139 VRIPENTPVGTPI---FIVNATDPDLGAGGSVLYS-FQPPSQFFAIDSARGIVTVIRE-L 193
Query: 854 DREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
D E Y+L++ A D T LS+ A L I+I D D P F + ++ + H
Sbjct: 194 DYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEH 248
Score = 77.8 bits (183), Expect = 2e-12
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 9/177 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL-DSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A+D D G+ + Y L+ L DS G + + +D + H L V
Sbjct: 2318 VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLN-----FTV 2372
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+AS +P + A+ V +E++D+NDN P F+ Y ++ E++P G +L V ATD D G
Sbjct: 2373 RASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSG 2432
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
Y L D + F+I+P +G + V + LDRE + AK+ NP V +
Sbjct: 2433 NFALIEYSLGDGESKFAINPTTGDIYVLSS--LDREKKDHYILTALAKD-NPGDVAS 2486
Score = 76.6 bits (180), Expect = 5e-12
Identities = 53/164 (32%), Positives = 83/164 (50%), Gaps = 12/164 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G + + L SGN F + + N G +F+ + LD + + + ++L
Sbjct: 1441 VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDRE-----ELDHYIL 1495
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF-YNISIVENLPNGFSVLQVMATDK 333
QV AS P + +++ +LD+NDN P E F YN+S+ EN+ G +V+QV ATD+
Sbjct: 1496 QVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDR 1555
Query: 334 DQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDREAHS 375
D G N +Y + + F +D SG + R DRE S
Sbjct: 1556 DIGINSVLSYYITEGNKDMTFRMDRISGEIATR-PAPPDRERQS 1598
Score = 74.5 bits (175), Expect = 2e-11
Identities = 84/328 (25%), Positives = 137/328 (41%), Gaps = 25/328 (7%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPLTV 134
+S ++ + I DV D PIF++ PY + E +P G I + G I T+
Sbjct: 216 LSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTI 275
Query: 135 PRGLTIFKDIRAFDR-----------DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
G T I A D D+ N S V G + S
Sbjct: 276 VSGNT--NSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTT 333
Query: 184 LR-KVLDYDAGDKEFQLVIMASGKRIHKEILFPEP--IHAIDQDLGVGATLRYEL-ISGN 239
V+D + EF + ++ F P I +D+D +G +E+ + GN
Sbjct: 334 FNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGN 393
Query: 240 DRKLFSLD--SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
+ F + SV G + + + ++ + + + A++ + P A+V+I L+
Sbjct: 394 NSHHFIISPTSVQGKADIRIRVAIPLDYET-VDRYDFDLFANE-SVPDHVGYAKVKITLI 451
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
+ NDN P F YNIS+ EN+ G SVL V+ATD D G GE +Y D FS+D
Sbjct: 452 NENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKD 511
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G + + + LD E + + A++
Sbjct: 512 TGLIMLIAR--LDYELIQRFTLTIIARD 537
Score = 73.7 bits (173), Expect = 3e-11
Identities = 87/331 (26%), Positives = 138/331 (41%), Gaps = 22/331 (6%)
Query: 73 GLNQISAYLSVTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT- 129
G + A S TV++ D+NDN P F + P+ V E P G + + + L
Sbjct: 864 GRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNG 923
Query: 130 -----IPLTVPRGLTIFKDIRAFDRDKPNTPNSDV-HYSIVSGNDDGHFALESSHKPVLL 183
+P+ +PR + + Y + D +SS + +
Sbjct: 924 LVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTI 983
Query: 184 LRKVLDY-DAGDKEFQLVIMAS-GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
VLD D F V S + + +E ++ D D+G+ A L Y + GN
Sbjct: 984 --HVLDVNDETPTFFPAVYNVSVSEDVPREFRVVW-LNCTDNDVGLNAELSYFITGGNVD 1040
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
FS+ + + + LD E A +L+ + T A V + +LD+ND
Sbjct: 1041 GKFSVGYRDA--VVRTVVGLDRE-TTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVND 1097
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
N P F Y S+ E++P G S+LQ+ ATD D+GE G Y++ + F I +G
Sbjct: 1098 NRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNG 1157
Query: 360 WLTVRNQTVLDREAHSS--LRMKVYAKETNP 388
L +R LDRE +SS L ++ Y + P
Sbjct: 1158 -LLMRGPRPLDRERNSSHVLIVEAYNHDLGP 1187
Score = 73.3 bits (172), Expect = 5e-11
Identities = 84/322 (26%), Positives = 134/322 (41%), Gaps = 36/322 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V++ + + ND+ P+F + YN ++ E + V ATD D G ++YF SD
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFF--SDDP 503
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F + TG++ + LD E ++ LT++ARD G DVNDN P
Sbjct: 504 DRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGG---GEETTGRVRINVLDVNDNVPT 560
Query: 1151 FY--AFDELLEWKHPEADEL------------SNHNFESVMMIPVYKATIEENAPIGTTV 1196
F A+ L P +L +N S++ + + + + G V
Sbjct: 561 FQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGV 620
Query: 1197 AKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
V + D+ NGLI ++ + G P L+ST + + V D E + P
Sbjct: 621 ISV-SRPLDYEQISNGLIYLTV----MAMDAGNPPLNSTVPVTIEVFD-----ENDNPPT 670
Query: 1257 FISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYILN-ENDTDIRRTFVIDPRNG 1313
F Y + + EN+ A ++ LN T + + I + E T R I+ R+G
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFR----INARSG 726
Query: 1314 TLYLVRSPDREVKDTYEVIVRA 1335
+ DRE K Y +IVRA
Sbjct: 727 EITTTSLLDRETKSEYILIVRA 748
Score = 70.9 bits (166), Expect = 2e-10
Identities = 88/331 (26%), Positives = 134/331 (40%), Gaps = 23/331 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA---PIGPSLT 129
G +SA V V I D NDN P+F Y V +DE T + I + A GP+ T
Sbjct: 1610 GTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGT 1669
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR---- 185
+ + G I R T ++ Y I G + P+L R
Sbjct: 1670 VTYAIVAG-NIVNTFRIDRHMGVITAAKELDYEISHGRYT-LIVTATDQCPILSHRLTST 1727
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEP------IHAIDQDLGVGATLRYELISGN 239
+ + D + E+ +P A D+D G + Y ++ G+
Sbjct: 1728 TTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGD 1787
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
F + V G L + K+++LD E N L + A P ++ V I +LD+
Sbjct: 1788 PLGEFVISPVEGVLRVRKDVELDRETIAFYN---LTICARDRGMPPLSSTMLVGIRVLDI 1844
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPR 357
NDN P NI+I EN P V V+A+D D G N T+ + + + AF I+
Sbjct: 1845 NDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINAT 1904
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
+G +TV LDRE ++ + K+ NP
Sbjct: 1905 TGIVTVNRP--LDRERIPEYKLTISVKD-NP 1932
Score = 69.7 bits (163), Expect = 6e-10
Identities = 61/215 (28%), Positives = 86/215 (40%), Gaps = 21/215 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
LI E+ P+G+++ +L A D+D+ P E R+F +
Sbjct: 41 LISEDTPVGSSVTQLLAQDMDND----------------PLVFGVSGEEASRFFAVEPDT 84
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G V + + L E SEF + S D + V + V DVND+ P F Y+ + E
Sbjct: 85 GVVWLRQPLDRETKSEFTVEFSVSDHQGVITR-KVNIQVGDVNDNAPTFHNQPYSVRIPE 143
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ V+ATD D G ++ Y QP F I G+++V ELD ET Y
Sbjct: 144 NTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF--FAIDSARGIVTVIRELDYETTQAY 201
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LTV A D DV D P F
Sbjct: 202 QLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIF 236
Score = 68.9 bits (161), Expect = 1e-09
Identities = 87/327 (26%), Positives = 137/327 (41%), Gaps = 27/327 (8%)
Query: 582 VGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP 641
+ + +G+SV Q+ D ND + G E FAVE +GV+ + L R +
Sbjct: 42 ISEDTPVGSSVTQLLAQDM--DNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKS 99
Query: 642 MYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF 701
+ E ++ ++ + I + V DVND + P + EN+ IF
Sbjct: 100 EFTVE-FSVSDHQGV-ITRKVNIQVGDVNDNAPTF---HNQPYSVRIPENTPVGT--PIF 152
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEF 760
N + G+V + Q + AI + G + + LD E Y++TV A
Sbjct: 153 IVNATDPDLGAGGSVLYSF---QPPSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATD 209
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ + + I I D D P+F + Y I E+S GT ++ II A D D+G
Sbjct: 210 QDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVR---IITAIDQDKG 266
Query: 821 TNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIM-YKLSLVARDT----GGLS 874
YT+ G +F +D +GV+ G LDRE + + L + T
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNG-LLDRENPLYSHGFILTVKGTELNDDRTP 325
Query: 875 SEAELI----IMIGDENDNKPEFNQIE 897
S+A + I++ D NDN PEFN E
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSE 352
Score = 67.3 bits (157), Expect = 3e-09
Identities = 54/173 (31%), Positives = 80/173 (46%), Gaps = 8/173 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y ++ GN F + NG L + LD E N ++ VL V+
Sbjct: 1124 LKATDADEGEFGRVWYRILHGNHGNNFRIHVSNG-LLMRGPRPLDRERN---SSHVLIVE 1179
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQG 336
A + + RV + + D+ND P F Y+ + + E G SV+ V ATD+D G
Sbjct: 1180 AYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSG 1239
Query: 337 ENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
+ G Y+ L +G F ID +G + N LD E +S M V A + P
Sbjct: 1240 DGGLVNYRILSGAEGKFEIDESTGLIITVN--YLDYETKTSYMMNVSATDQAP 1290
Score = 62.9 bits (146), Expect = 7e-08
Identities = 53/170 (31%), Positives = 77/170 (45%), Gaps = 8/170 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D + Y ++S + F + G + LD E + L V
Sbjct: 583 LRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQ-ISNGLIYLTV 641
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A NP + V IE+ D NDN P F Y +S+VEN+ G +VL + ATD D+
Sbjct: 642 MAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRS 701
Query: 337 -ENGE--FTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
E G+ Y L+ F I+ RSG +T ++LDRE S + V A
Sbjct: 702 REYGQESIIYSLEG-STQFRINARSGEIT--TTSLLDRETKSEYILIVRA 748
Score = 62.5 bits (145), Expect = 9e-08
Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 15/225 (6%)
Query: 236 ISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+SG + + F+++ G ++L + LD + + + F ++ S + +V I
Sbjct: 69 VSGEEASRFFAVEPDTGVVWLRQPLDRETK-----SEFTVEFSVSDHQGVITR---KVNI 120
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
++ D+NDN P F Y++ I EN P G + V ATD D G G Y P F+I
Sbjct: 121 QVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAI 180
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS-VVGTFADSQRIAK--WRRQPLETN 411
D G +TV + LD E + ++ V A + + + + T A+ I P+ N
Sbjct: 181 DSARGIVTVIRE--LDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFIN 238
Query: 412 APLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
P Y GT I D+ + T++ N N+
Sbjct: 239 LPYSTNIYEH-SPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNS 282
Score = 61.7 bits (143), Expect = 2e-07
Identities = 59/203 (29%), Positives = 92/203 (45%), Gaps = 23/203 (11%)
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
G + I E IP+ + + ++ A D D GLNG +RY F L +F+I
Sbjct: 2617 GTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSF----------LKTAGNRDWEFFII 2666
Query: 995 NERHGHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKK-- 1047
+ G + A+ L ES+ + L + A D G ++V ++D++D+ P+F +
Sbjct: 2667 DPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPP 2726
Query: 1048 ----TWYNFNVEEAQYTRRVLGKV-DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
+ V E ++G V A DAD G NA + YFI + + F + P G L
Sbjct: 2727 KGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQP-DGCL 2785
Query: 1103 SVNGELDRETEDKYILTVVARDN 1125
V +LDRE E + V A N
Sbjct: 2786 LVLRDLDREREAIFSFIVKASSN 2808
Score = 60.5 bits (140), Expect = 3e-07
Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
N F+++ GS+ ++ ++ + + V+ + + A++ + +LD
Sbjct: 2226 NQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLD 2285
Query: 299 LNDNLPEFE---VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFS 353
+NDN P+F+ + +Y I+E G +++ V A D D+G NG TY L D P G
Sbjct: 2286 VNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQ 2345
Query: 354 IDPRSGWLTVRNQTVLDREAH 374
++ S + N+TV E H
Sbjct: 2346 LEDSSAGKVIANRTVDYEEVH 2366
Score = 58.4 bits (135), Expect = 1e-06
Identities = 41/126 (32%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + Y DR FSLD G + L LD + F L + A
Sbjct: 484 ATDNDAGTFGEVSYFFSDDPDR--FSLDKDTGLIMLIARLDYEL-----IQRFTLTIIAR 536
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
T RV I +LD+NDN+P F+ D Y ++ EN P+ ++++ ATD+D N
Sbjct: 537 DGGGEETTG--RVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNN 594
Query: 340 EFTYQL 345
+ TY +
Sbjct: 595 QITYSI 600
Score = 58.4 bits (135), Expect = 1e-06
Identities = 114/498 (22%), Positives = 199/498 (39%), Gaps = 50/498 (10%)
Query: 83 VTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPRGL 138
+ VY+E D+NDN PIF Y V E P G A G I ++ G
Sbjct: 2386 IPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGE 2445
Query: 139 TIFK------DI---RAFDRDKPNTPNSDVHYSI--VSGNDDGHFALESSHKPVLLLRKV 187
+ F DI + DR+K + HY + ++ ++ G A V ++ +V
Sbjct: 2446 SKFAINPTTGDIYVLSSLDREKKD------HYILTALAKDNPGDVASNRRENSVQVVIQV 2499
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
LD + +F ++ ++ + A DQD G L Y L G + F +
Sbjct: 2500 LDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSL-EGPGVEAFHV 2558
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D +G + ++ L F L V A+ P + +E++D+NDN P F
Sbjct: 2559 DMDSGLVTTQRPLQ-------SYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVF 2611
Query: 307 --EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-----AFSIDPRSG 359
+ + I E +P +V +V ATDKD+G NG Y G F IDP SG
Sbjct: 2612 VRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISG 2671
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTY 419
+ + LDRE+ + + + A + V ++A + ++ N PL +
Sbjct: 2672 LIQTAQR--LDRESQAVYSLILVASDLGQPVPYETMQPLQVA---LEDIDDNEPL----F 2722
Query: 420 VFPDKVGTKTENIEYYDEQLMSFVNVEVT-LLDANDNNPVFVPSNLYEFSMKSNAKVGTV 478
V P K + + + + + VT +DA++ V + + + N +
Sbjct: 2723 VRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPD 2782
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA 538
+ D D + + + ++ +SN + T P +P T+ + L+ + +
Sbjct: 2783 GCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSP---TLDLVADLTLQEVRVVLEDI 2839
Query: 539 SDQPANPSERRYSLAVVT 556
+DQP ++ Y+ V T
Sbjct: 2840 NDQPPRFTKAEYTAGVAT 2857
Score = 50.8 bits (116), Expect = 3e-04
Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 10/129 (7%)
Query: 230 TLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
T R++ + K LF +D++ G + ++ +D + + + + L V A P +
Sbjct: 1347 TYRFDAYTSTQAKALFKIDAITGVITVQGLVDRE-----KGDFYTLTVVADD-GGPKVDS 1400
Query: 289 QARVEIELLDLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-- 345
+V I +LD NDN P F+ + +SI E+ P G V V A D D G NG+ + L
Sbjct: 1401 TVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLAS 1460
Query: 346 DDPKGAFSI 354
+ GAF I
Sbjct: 1461 GNIAGAFEI 1469
Score = 49.2 bits (112), Expect = 9e-04
Identities = 79/323 (24%), Positives = 135/323 (41%), Gaps = 34/323 (10%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA--PIGPS--LTIPLTVP- 135
+ V + + DVND P F + +V E P G + GP+ LT L P
Sbjct: 2493 VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPG 2552
Query: 136 -RGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
+ D +P ++V+ D G L + +LL +V+D +
Sbjct: 2553 VEAFHVDMDSGLVTTQRPLQSYEKFSLTVVA-TDGGEPPLWGT---TMLLVEVIDVNDNR 2608
Query: 195 KEFQLVIMASGKRIHKEILFPE---PIHAIDQDLGVGATLRYELI--SGN-DRKLFSLDS 248
F + I +EI ++A D+D G+ +RY + +GN D + F +D
Sbjct: 2609 PVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDP 2668
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL--KTAQARVEIELLDLNDNLPEF 306
++G + + LD +++ + L + AS L P+ +T Q +++ L D++DN P F
Sbjct: 2669 ISGLIQTAQRLDRESQ-----AVYSLILVASDLGQPVPYETMQP-LQVALEDIDDNEPLF 2722
Query: 307 ------EVDFYNISIVENLPNGFSVLQVM-ATDKDQGENGEFTYQL--DDPKGAFSIDPR 357
+ +++ E+ P G V V A D D+G N Y + + + F + P
Sbjct: 2723 VRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQP- 2781
Query: 358 SGWLTVRNQTVLDREAHSSLRMK 380
G L V +REA S +K
Sbjct: 2782 DGCLLVLRDLDREREAIFSFIVK 2804
Score = 45.2 bits (102), Expect = 0.014
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 15/137 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G A + Y + +GN+ K F L +G L + ++LD + E +F+++ ++
Sbjct: 2753 AVDADEGPNAIVYYFIAAGNEEKNFHLQP-DGCLLVLRDLDREREAIF---SFIVKASSN 2808
Query: 280 QLNNPLKTAQA-----------RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ P + V + L D+ND P F Y + + G ++QV
Sbjct: 2809 RSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQV 2868
Query: 329 MATDKDQGENGEFTYQL 345
+A D D G N Y +
Sbjct: 2869 LALDADIGNNSLVFYSI 2885
Score = 44.8 bits (101), Expect = 0.018
Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 28/152 (18%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN--FKM 1290
+ TA + VTV DV D ++P+F+ YE + E++ ++ L T+ E ++
Sbjct: 1083 TGTATVFVTVLDVND-----NRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRV 1137
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRAERQKYSRELPHMIY 1349
Y IL+ N + F I NG L P DRE ++ +IV A Y+ +L
Sbjct: 1138 WYRILHGNHGN---NFRIHVSNGLLMRGPRPLDRERNSSHVLIVEA----YNHDL----- 1185
Query: 1350 PVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
G + V+V+V ++D+ND +P FT
Sbjct: 1186 --------GPMRSSVRVIVYVEDINDEAPVFT 1209
Score = 40.7 bits (91), Expect = 0.30
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 12/151 (7%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS----LTIPLTV 134
A S+ + D+ VP P V ++++ + +F+ P G LT+P
Sbjct: 2685 AVYSLILVASDLGQPVPYETMQPLQVALEDID---DNEPLFVRPPKGSPQYQLLTVPEHS 2741
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
PRG + A D D+ PN+ V+Y I +GN++ +F L+ LL+ + LD + +
Sbjct: 2742 PRGTLVGNVTGAVDADEG--PNAIVYYFIAAGNEEKNFHLQPD--GCLLVLRDLDRER-E 2796
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDL 225
F ++ AS R P P + DL
Sbjct: 2797 AIFSFIVKASSNRSWTPPRGPSPTLDLVADL 2827
Score = 37.5 bits (83), Expect = 2.8
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 1441 ATDSDIGINADIRYQILNEQAPR----FAIDPVSGTVRVVAALARDAGRVF 1487
ATD D G+N +RY L R F IDP+SG ++ L R++ V+
Sbjct: 2637 ATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVY 2687
>UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000007226 - Anopheles gambiae
str. PEST
Length = 1645
Score = 160 bits (388), Expect = 3e-37
Identities = 134/475 (28%), Positives = 216/475 (45%), Gaps = 27/475 (5%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + + V ++DANDN P F P+ ++ + T I V A DPD G NG V Y
Sbjct: 529 RLATTILFAVNVIDANDNPPAF-PNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRY 587
Query: 498 DL--QRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLA 553
++ Q + F INP TG + E + L V A+DQ A P++R +
Sbjct: 588 EIAHQDPQDGDGERHFGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEK 647
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+VT+ + P F P F V ++ +G +V +I D + Y LL G
Sbjct: 648 LVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLEYALLDG 707
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+ FA+E +G++ + D L R Y + V++ + S T T+ + D ND
Sbjct: 708 -DAPKKFALERETGLLKLRDTLDRETEDSYRLK-VSVTDGIQ-STETTITIQITDTNDNP 764
Query: 674 GVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V + A+S F + EN+ G +G I T+ ++ G V + A D +
Sbjct: 765 PVFAEPAYS---FDIPENAQRGFHVGVIAATDPDNVIPPNNGYVITVRAYDADTPPRFRL 821
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A G I T LD E +Y T++A+ + A + +TI ++D NDN P F T
Sbjct: 822 DASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPAFGAPT 881
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--------MFDVDENT 843
+ + + K G + KA D DEG NA +Y++ E +F+++ +T
Sbjct: 882 FHVNVPDRIKPGQFVFG---AKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINTDT 938
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
G + + LDRE Y L + A D G L+ A +++ + D+NDN P+F ++
Sbjct: 939 GEI-YTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNVLDKNDNPPKFTRL 992
Score = 145 bits (351), Expect = 9e-33
Identities = 208/938 (22%), Positives = 369/938 (39%), Gaps = 99/938 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V+VT+ D ND+ PVF ++ YE S+ + V + + A D D+G NG + Y
Sbjct: 210 LTTRTTVQVTVEDVNDHTPVFDHTS-YETSLLESMPVNSRFFALAASDADVGPNGRISYA 268
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES---PILEGRHALFVEA--SDQPANPSERRYSLA 553
+ ++ F I+ G + S L G+ L +EA SD A R +
Sbjct: 269 IVEGNDRE--EDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIK 326
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
V +V + P F+ APY + IGT + ++ +DA E DV Y +
Sbjct: 327 VFITDVN-------DNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYIS 379
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLSIVTNATVHVVDV 669
G FA+++ +G IT+ L R Y VA + LS T T+ V+D
Sbjct: 380 EG-NRAERFAIDDSTGQITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVLDE 438
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA--NQQDVT 727
ND+ + I V+ G + + T++ + F IA N++D
Sbjct: 439 NDDAPEFTQTLSQIAI--VETTPIGTELMRFRATDLDL---GANAQIAFSIAAGNRRDTF 493
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
A++ G ++ + LD E Y + + A + G A + + D NDNPP F
Sbjct: 494 HIDALS--GALYLHRALDYEDTQSYSLNISAA-DGGNPRLATTILFAVNVIDANDNPPAF 550
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ I E + T I + A D D G N Y + + + D + + G+
Sbjct: 551 PNTAIVRQIREGIPLNTPIVT---VTAEDPDSGLNGKVRYEIAHQDPQDGDGERHFGINP 607
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
G +++ L L+ R+ L ++ D+ P ++ V +
Sbjct: 608 TTG--------VIHTLHLIDREA---IDTYRLTVLATDQA--APPAQRLSAEKLVTV--- 651
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
+ V KN L +F + E++ +G T+ ++ A D D+ G++
Sbjct: 652 --------IIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVGQTVARITATDPDT--LGKLE 701
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNL 1025
Y L DA + F + G + + +L E+E +RL +S DG
Sbjct: 702 YAL----------LDGDA---PKKFALERETGLLKLRDTLDRETEDSYRLKVSVTDGIQS 748
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD--FGQNANLTYF 1083
+ ++ + + D ND+ PVF + Y+F++ E +G + ATD D N
Sbjct: 749 TET-TITIQITDTNDNPPVFAEPAYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVIT 807
Query: 1084 IQPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
++ D D P F + +G ++ LD E Y T++A+D+
Sbjct: 808 VRAYDADTPPRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDV 867
Query: 1142 XDVNDNSPKFYA--F-----DELLEWKHPEADEL--SNHNFESVMMIPVYKATIEENAPI 1192
DVNDNSP F A F D + + + + + ++ ++ IE +
Sbjct: 868 QDVNDNSPAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVIEAATEL 927
Query: 1193 GTTVAKVFANDTDFIGNGNGLILYSLPQRK---NQQNLGLPSLSSTAILMVTVADV---P 1246
T + ++ DT I L + Q + G+P L+ +A ++V V D P
Sbjct: 928 STPIFEI-NTDTGEIYTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNVLDKNDNP 986
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILN----ENDTDI 1302
+ +I + ++ P+ + + ++ F+ YY N +
Sbjct: 987 PKFTRLFSDEYILKVAAVDGAWRTETPLTITIQDQNDNAPEFEHSYYSFNFRELQKSVTF 1046
Query: 1303 RRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
R F+++ G + + D ++ Y++ + AE Y
Sbjct: 1047 RNDFMVNSVTGAVSIRNPLDYDLIQVYQLNITAEDLGY 1084
Score = 142 bits (344), Expect = 7e-32
Identities = 137/474 (28%), Positives = 214/474 (45%), Gaps = 50/474 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VT+LD NDN P+F S+ Y S+ + GT + +V A D DLG N + Y L
Sbjct: 1 VNVTILDVNDNPPIFDHSD-YIVSLNESVLPGTPVLQVMASDSDLGDNSKITYYLADAE- 58
Query: 505 LTITSPFKINPNTGTVSV-AESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F ++P TG + A L + L V A D + P S A V++ V
Sbjct: 59 ----TQFTVDPETGIATRRALDRELVAAYTLVVIARDHGSPPQS---SSATVSVAV-EDA 110
Query: 564 KGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG-YEEGVP 619
N P++ P P V + GT + Q+ D E + V Y+L+ G +
Sbjct: 111 NDNSPELYPRAFFVP----VAEDAPEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAAL 166
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAV-ALQENAN------LSIVTNATVHVVDVNDE 672
FA++ +G +T+ L + +P++ V +L+ +A L+ T V V DVND
Sbjct: 167 FAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVND- 225
Query: 673 RGVLLKGAHSPIIFHVKENSA---GAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTD 728
H+P+ H ++ + F +S G G + + I D +
Sbjct: 226 --------HTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDREE 277
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEF--NKGVISGAGIYQVTIYIEDENDNPP 785
D +I + +G I T++ DRE + + G + ++ ++I D NDN P
Sbjct: 278 DFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDVNDNAP 337
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKEMFDVDENTG 844
VF A Y I E + IGT++ + DADEG N +F Y G E F +D++TG
Sbjct: 338 VFVRAPYRVQISEGASIGTQLVR---VYTHDADEGLNGDVFYYISEGNRAERFAIDDSTG 394
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQ 895
+ + +LDRE Y+L++VA D LS+ + I + DEND+ PEF Q
Sbjct: 395 QIT-LARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQ 447
Score = 124 bits (298), Expect = 2e-26
Identities = 132/484 (27%), Positives = 200/484 (41%), Gaps = 56/484 (11%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++P+ + L A D D G NG+I Y + + + F I+ R+G +
Sbjct: 241 ESMPVNSRFFALAASDADVGPNGRISYAI------------VEGNDREEDFSIDSRNGFI 288
Query: 1002 IVARSLPPE-----SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
RS E S L + D G L D + ++VF+ DVND+ PVF + Y +
Sbjct: 289 RTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDVNDNAPVFVRAPYRVQI 348
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E L +V DAD G N ++ Y+I + F I TG +++ LDRET
Sbjct: 349 SEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAERFAIDDSTGQITLARALDRETTA 408
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y LTVVA D D ND++P+F L + E +
Sbjct: 409 SYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEF--TQTLSQIAIVETTPIGT---- 462
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG-LILYSLPQRKNQQNLGL---- 1229
+M + NA I ++A DT I +G L L+ ++ Q+ L
Sbjct: 463 ELMRFRATDLDLGANAQIAFSIAAGNRRDTFHIDALSGALYLHRALDYEDTQSYSLNISA 522
Query: 1230 -----PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLT 1282
P L++T + V V D D + P F + +I E + N P+ V+
Sbjct: 523 ADGGNPRLATTILFAVNVIDAND-----NPPAFPNTAIVRQIREGIPLNTPIVTVTAEDP 577
Query: 1283 EHYENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ N K+RY I +++ D D R F I+P G ++ + DRE DTY + V A Q
Sbjct: 578 DSGLNGKVRYEIAHQDPQDGDGERHFGINPTTGVIHTLHLIDREAIDTYRLTVLATDQ-- 635
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQ 1400
P A+ L V + V + D ND+ PKF N PLV ++ G
Sbjct: 636 -------AAPPAQR-LSAEKLVTVIIRVNVLDKNDSPPKFQ--NLPLVFSVSEDLAVGQT 685
Query: 1401 VMQL 1404
V ++
Sbjct: 686 VARI 689
Score = 118 bits (284), Expect = 1e-24
Identities = 126/472 (26%), Positives = 201/472 (42%), Gaps = 38/472 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V ++V + D NDN PVFV + Y + A +GT + +V D D G NG V Y
Sbjct: 318 RLRDRVKIKVFITDVNDNAPVFVRAP-YRVQISEGASIGTQLVRVYTHDADEGLNGDVFY 376
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ + F I+ +TG +++A + E + + A+ R + VTI
Sbjct: 377 YISEGNR---AERFAIDDSTGQITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTI 433
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYE 615
EV D P+F + + IGT + + R D +++ + G
Sbjct: 434 EVL----DENDDAPEFTQTLSQIAIVETTPIGTELMRFRATDLDLGANAQIAFSIAAGNR 489
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERG 674
F ++ SG + + L + Y A N L+ V+V+D ND
Sbjct: 490 RDT-FHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPP 548
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDD---- 729
++ I+ ++E G + T + +G G VR+ IA+Q D
Sbjct: 549 AF---PNTAIVRQIRE---GIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERH 602
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV----ISGAGIYQVTIYIE--DEND 782
I G I T +DRE D YR+TV+A +S + V I + D+ND
Sbjct: 603 FGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKND 662
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDE 841
+PP F++ + E+ +G + I ATD D T Y L G+ + F ++
Sbjct: 663 SPPKFQNLPLVFSVSEDLAVGQTVAR---ITATDPD--TLGKLEYALLDGDAPKKFALER 717
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
TG++K + D+LDRE + Y+L + D G S+E + I I D NDN P F
Sbjct: 718 ETGLLK-LRDTLDRETEDSYRLKVSVTD-GIQSTETTITIQITDTNDNPPVF 767
Score = 117 bits (282), Expect = 2e-24
Identities = 126/471 (26%), Positives = 203/471 (43%), Gaps = 37/471 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V + DANDN+P P + + +A GT+I ++ A D D G+N +V Y+L
Sbjct: 99 SSATVSVAVEDANDNSPELYPRAFF-VPVAEDAPEGTLIAQLTATDRDEGENAIVQYELV 157
Query: 501 RTSNLTITSPFKINPNTGTV----SVAESPILEGRH----ALFVEASDQPANPSERRYSL 552
T + F I+ TG + S+ +SP R +L V A+D + P R ++
Sbjct: 158 GGPT-TDAALFAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTV 216
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDL 610
V +V T P F YE + ++ + + + +DA +SY +
Sbjct: 217 QVTVEDVNDHT-------PVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAI 269
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRY---NRPMYDFEAVALQENA-NLSIVTNATVHV 666
+ G + F+++ R+G I R + EA A L V +
Sbjct: 270 VEGNDREEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFI 329
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
DVND V ++ + I S GA+IG + G F ++ +
Sbjct: 330 TDVNDNAPVFVRAPYRVQI------SEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNR 383
Query: 727 TDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ AI + G I + LDRE YR+TV+A + VTI + DEND+ P
Sbjct: 384 AERFAIDDSTGQITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAP 443
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTG 844
F + I+E + IGTE+ +ATD D G NA +++ G ++ F +D +G
Sbjct: 444 EFTQTLSQIAIVETTPIGTELMR---FRATDLDLGANAQIAFSIAAGNRRDTFHIDALSG 500
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ ++ +LD E Y L++ A D G L++ + + D NDN P F
Sbjct: 501 AL-YLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPPAF 550
Score = 91.1 bits (216), Expect = 2e-16
Identities = 129/488 (26%), Positives = 206/488 (42%), Gaps = 52/488 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMV 495
E+L++ + + V +LD ND+ P F L FS+ + VG + ++ A DPD LG+
Sbjct: 646 EKLVTVI-IRVNVLDKNDSPPKFQNLPLV-FSVSEDLAVGQTVARITATDPDTLGKLEYA 703
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
L D F + TG + + ++ E + ++ S S +
Sbjct: 704 LLDGDAPKK------FALERETGLLKLRDTLDRETEDSYRLKVSVTDGIQSTE----TTI 753
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLH 612
TI++T T N P F Y F + N G VG I D N+ +
Sbjct: 754 TIQIT-DTNDNPPV---FAEPAYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVITVR 809
Query: 613 GYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVD 668
Y+ P F ++ SG IT L + P+Y F +A + + + N T+ V D
Sbjct: 810 AYDADTPPRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQD 869
Query: 669 VNDERGVL-LKGAHSPIIFHVKENSA--GA-AIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
VND H + +K GA AI + N +Y TG + A +
Sbjct: 870 VNDNSPAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVIE---AATE 926
Query: 725 DVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAE-FNKGVISGAGIYQVTIYIEDEND 782
T I D G I+T LDRE D+ + T+I E ++GV G V + + D+ND
Sbjct: 927 LSTPIFEINTDTGEIYTTTRLDRE--DIAQYTLIVEAVDQGVPQLTGSATVLVNVLDKND 984
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFG-EGKEM---- 836
NPP F + +I++ + + + + + T D+ NA F ++ + +E+
Sbjct: 985 NPPKFTRLFSDEYILKVAAVDGAWRTETPLTITIQDQNDNAPEFEHSYYSFNFRELQKSV 1044
Query: 837 -----FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE----AELIIMIGDEN 887
F V+ TG V I + LD + +Y+L++ A D G A++II I D N
Sbjct: 1045 TFRNDFMVNSVTGAVS-IRNPLDYDLIQVYQLNITAEDLGYKPKRSIAMAQIIISIQDGN 1103
Query: 888 DNKPEFNQ 895
D PEF +
Sbjct: 1104 D-PPEFQR 1110
Score = 88.6 bits (210), Expect = 1e-15
Identities = 106/416 (25%), Positives = 165/416 (39%), Gaps = 33/416 (7%)
Query: 938 FLIP--ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
F +P E+ P GT I +L A D D G N ++YE + + DA +
Sbjct: 122 FFVPVAEDAPEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAALFAIDATTGALTLRSS 181
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ V R P + L +SA DGG+ L +V+V V+DVNDH PVF T Y +
Sbjct: 182 LQKSPKPVHR---PGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVNDHTPVFDHTSYETS 238
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E+ + A+DAD G N ++Y ++ +D + F I G + DRE
Sbjct: 239 LLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDREEDFSIDSRNGFIRTRRSFDREA 298
Query: 1113 ---EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
+ L DNG DVNDN+P F + P ++S
Sbjct: 299 LGGQSFLALEATVSDNG-AVRLRDRVKIKVFITDVNDNAPVFV--------RAPYRVQIS 349
Query: 1170 NHNFESVMMIPVYKATIEE--NAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQN 1226
++ VY +E N + +++ + I + G I L R+ +
Sbjct: 350 EGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAERFAIDDSTGQITLARALDRETTAS 409
Query: 1227 LGLPSLSSTA-----ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL 1281
L ++ A + T + E D P F ++ I E EL+
Sbjct: 410 YRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTELMRFRA 469
Query: 1282 T--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
T + N ++ + I N D TF ID +G LYL R+ D E +Y + + A
Sbjct: 470 TDLDLGANAQIAFSIAAGNRRD---TFHIDALSGALYLHRALDYEDTQSYSLNISA 522
Score = 87.4 bits (207), Expect = 3e-15
Identities = 106/390 (27%), Positives = 165/390 (42%), Gaps = 45/390 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V + DVND+ P+F + Y ++ E+ + +V A+D+D G N+ +TY++ +D +
Sbjct: 1 VNVTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITYYL--ADAE 58
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F + P TG+ + LDRE Y L V+ARD+G D NDNSP+
Sbjct: 59 TQFTVDPETGI-ATRRALDRELVAAYTLVVIARDHG-SPPQSSSATVSVAVEDANDNSPE 116
Query: 1151 FY--AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG-TTVAKVFAND--TD 1205
Y AF + PE ++ + A ++ G TT A +FA D T
Sbjct: 117 LYPRAFFVPVAEDAPEGTLIA--QLTATDRDEGENAIVQYELVGGPTTDAALFAIDATTG 174
Query: 1206 FIGNGNGLILYSLPQRK---------NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
+ + L P + + + G P L++ + VTV DV D PV
Sbjct: 175 ALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVNDHT-----PV 229
Query: 1257 FISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGT 1314
F YE + E+ VN+ ++ + + N ++ Y I+ ND + F ID RNG
Sbjct: 230 FDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDRE--EDFSIDSRNGF 287
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
+ RS DRE + + D + VK+ V I DVN
Sbjct: 288 IRTRRSFDREALGGQSFLA--------------LEATVSDNGAVRLRDRVKIKVFITDVN 333
Query: 1375 DNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
DN+P F P I A G Q++++
Sbjct: 334 DNAPVFVRA--PYRVQISEGASIGTQLVRV 361
Score = 87.0 bits (206), Expect = 3e-15
Identities = 120/478 (25%), Positives = 187/478 (39%), Gaps = 43/478 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL---GQNGMVLYDLQR 501
+ + + D NDN PVF Y F + NA+ G +G + A DPD NG V+ R
Sbjct: 753 ITIQITDTNDNPPVFAEP-AYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVI--TVR 809
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ F+++ ++G ++ A E Q ++ +E R +L +TI+V +
Sbjct: 810 AYDADTPPRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDV-Q 868
Query: 562 GTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P GAP + V + G V + D E V+ LL+ GV
Sbjct: 869 DVNDNSPAF----GAPTFHVNVPDRIKPGQFVFGAKAIDRDE--GVNARLLYSIHTGVIE 922
Query: 621 AVEERS----------GVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
A E S G I L R + Y A+ + L+ V+V+D
Sbjct: 923 AATELSTPIFEINTDTGEIYTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNVLDK 982
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG--------TGNVRFLIA 721
ND + I V + N + N R L
Sbjct: 983 NDNPPKFTRLFSDEYILKVAAVDGAWRTETPLTITIQDQNDNAPEFEHSYYSFNFRELQK 1042
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE-FNKGVISGAGIYQVTIYIEDE 780
+ D + + G + + PLD + VY++ + AE + Q+ I I+D
Sbjct: 1043 SVTFRNDFMVNSVTGAVSIRNPLDYDLIQVYQLNITAEDLGYKPKRSIAMAQIIISIQDG 1102
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKE-MFD 838
ND PP F+ YE + E IGT++ ++KA D D N F +++ G + F
Sbjct: 1103 ND-PPEFQRDLYEASVSEGDPIGTKV---IVVKAVDKDVRPQNNQFSFSIIGGNNDHSFK 1158
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--IMIGDENDNKPEFN 894
+D +G ++ LDRE +KL L A DTG + I + D NDN P F+
Sbjct: 1159 IDPQSGQIE-TARKLDRETVPTHKLLLGAIDTGTPPQTGTTVVRITVTDINDNGPTFD 1215
Score = 85.8 bits (203), Expect = 8e-15
Identities = 86/307 (28%), Positives = 140/307 (45%), Gaps = 25/307 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTI 140
V V I DVNDN PIF + Y V+++E G + + +G + I + T
Sbjct: 1 VNVTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITYYLADAETQ 60
Query: 141 FK---DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
F + R + + +V D G +SS V V DA D
Sbjct: 61 FTVDPETGIATRRALDRELVAAYTLVVIARDHGS-PPQSSSATV----SVAVEDANDNSP 115
Query: 198 QLVIMASGKRIHKEILFPE-----PIHAIDQDLGVGATLRYELISG--NDRKLFSLDSVN 250
+L A + ++ PE + A D+D G A ++YEL+ G D LF++D+
Sbjct: 116 ELYPRAFFVPVAEDA--PEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAALFAIDATT 173
Query: 251 GSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G+L L L + + T + L+V A+ +P T + V++ + D+ND+ P F+
Sbjct: 174 GALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVNDHTPVFDHT 233
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQ 366
Y S++E++P + A+D D G NG +Y + +D + FSID R+G+ +R +
Sbjct: 234 SYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDREEDFSIDSRNGF--IRTR 291
Query: 367 TVLDREA 373
DREA
Sbjct: 292 RSFDREA 298
Score = 84.6 bits (200), Expect = 2e-14
Identities = 88/339 (25%), Positives = 147/339 (43%), Gaps = 29/339 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G ++ +V V +EDVND+ P+F T Y ++ E P + F A +GP+ I
Sbjct: 206 GSPPLTTRTTVQVTVEDVNDHTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRI 265
Query: 131 PLTVPRGLTIFKDI------------RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
+ G +D R+FDR+ + + VS D+G L
Sbjct: 266 SYAIVEGNDREEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVS--DNGAVRLRDRV 323
Query: 179 KPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
K + + V D + V ++ G I +++ ++ D D G+ + Y +
Sbjct: 324 KIKVFITDVNDNAPVFVRAPYRVQISEGASIGTQLV---RVYTHDADEGLNGDVFYYISE 380
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN + F++D G + L + LD + + + V+ AS+ + +A V IE+L
Sbjct: 381 GNRAERFAIDDSTGQITLARALDRETTASYRLT--VVAHDASKQHR--LSASTTVTIEVL 436
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
D ND+ PEF I+IVE P G +++ ATD D G N + + + + + F ID
Sbjct: 437 DENDDAPEFTQTLSQIAIVETTPIGTELMRFRATDLDLGANAQIAFSIAAGNRRDTFHID 496
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
SG L + LD E S + + A + NP + T
Sbjct: 497 ALSGALYLHR--ALDYEDTQSYSLNISAADGGNPRLATT 533
Score = 83.0 bits (196), Expect = 6e-14
Identities = 89/332 (26%), Positives = 145/332 (43%), Gaps = 31/332 (9%)
Query: 78 SAYLSVTVYIEDVNDN----------VPIFLDTPYHVTVDELTPT----GEKAFIFLIAP 123
S+ +V+V +ED NDN VP+ D P + +LT T GE A +
Sbjct: 98 SSSATVSVAVEDANDNSPELYPRAFFVPVAEDAPEGTLIAQLTATDRDEGENAIVQYELV 157
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPN--SDVHYSIVSGNDDGHFALESSHKPV 181
GP+ L T +R+ + P + V VS D G L +
Sbjct: 158 GGPTTDAALFAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQ 217
Query: 182 LLLRKVLDYD-AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ + V D+ D + ++ + A D D+G + Y ++ GND
Sbjct: 218 VTVEDVNDHTPVFDHTSYETSLLESMPVNSRFF---ALAASDADVGPNGRISYAIVEGND 274
Query: 241 RKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL-- 297
R+ FS+DS NG + + D +A L +F L ++A+ +N + RV+I++
Sbjct: 275 REEDFSIDSRNGFIRTRRSFDREA---LGGQSF-LALEATVSDNGAVRLRDRVKIKVFIT 330
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSID 355
D+NDN P F Y + I E G +++V D D+G NG+ Y + + A F+ID
Sbjct: 331 DVNDNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAERFAID 390
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
+G +T+ LDRE +S R+ V A + +
Sbjct: 391 DSTGQITLAR--ALDRETTASYRLTVVAHDAS 420
Score = 79.8 bits (188), Expect = 5e-13
Identities = 50/173 (28%), Positives = 84/173 (48%), Gaps = 14/173 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D DLG A + + + +GN R F +D+++G+L+L + LD + ++ L + A+
Sbjct: 469 ATDLDLGANAQIAFSIAAGNRRDTFHIDALSGALYLHRALDYE-----DTQSYSLNISAA 523
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP + ++D NDN P F I E +P ++ V A D D G NG
Sbjct: 524 DGGNPRLATTILFAVNVIDANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNG 583
Query: 340 EFTYQL--DDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ Y++ DP+ F I+P +G + ++DREA + R+ V A +
Sbjct: 584 KVRYEIAHQDPQDGDGERHFGINPTTG--VIHTLHLIDREAIDTYRLTVLATD 634
Score = 71.7 bits (168), Expect = 1e-10
Identities = 38/94 (40%), Positives = 58/94 (61%), Gaps = 3/94 (3%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V + +LD+NDN P F+ Y +S+ E++ G VLQVMA+D D G+N + TY L D +
Sbjct: 1 VNVTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITYYLADAETQ 60
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F++DP +G T R LDRE ++ + V A++
Sbjct: 61 FTVDPETGIATRR---ALDRELVAAYTLVVIARD 91
Score = 68.5 bits (160), Expect = 1e-09
Identities = 80/325 (24%), Positives = 138/325 (42%), Gaps = 25/325 (7%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPL 132
+++SA +VT+ + D ND+ P F T + + E TP G + F + G + I
Sbjct: 423 HRLSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTELMRFRATDLDLGANAQIAF 482
Query: 133 TVPRGL---TIFKDIR--AFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRK 186
++ G T D A + YS+ +S D G+ L ++ +L
Sbjct: 483 SIAAGNRRDTFHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATT---ILFAVN 539
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELI-----SG 238
V+D A D A ++I + I PI + D D G+ +RYE+ G
Sbjct: 540 VID--ANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDG 597
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA--SQLNNPLKTAQARVEIEL 296
+ + F ++ G + +D +A + A +Q + K + + +
Sbjct: 598 DGERHFGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNV 657
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
LD ND+ P+F+ S+ E+L G +V ++ ATD D E+ D F+++
Sbjct: 658 LDKNDSPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLEYALLDGDAPKKFALER 717
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKV 381
+G L +R+ LDRE S R+KV
Sbjct: 718 ETGLLKLRD--TLDRETEDSYRLKV 740
Score = 66.9 bits (156), Expect = 4e-09
Identities = 125/516 (24%), Positives = 211/516 (40%), Gaps = 84/516 (16%)
Query: 925 NKFALDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
N LDV+ P+F + E++ GT ++++ A D D G N +I Y Y+
Sbjct: 2 NVTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITY------YL- 54
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
ADA + F ++ G + R+L E + + L + A D G+ + + +V V
Sbjct: 55 -----ADA---ETQFTVDPETG-IATRRALDRELVAAYTLVVIARDHGSPPQSSSATVSV 105
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDL 1091
V+D ND+ P + V E ++ ++ ATD D G+NA + Y + P+
Sbjct: 106 AVEDANDNSPELYPRAFFVPVAEDAPEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAA 165
Query: 1092 PFEISPLTGVLSVNGELDRETEDKY----ILTV-VARDNGXXXXXXXXXXXXXXXXDVND 1146
F I TG L++ L + + + +L++ V+ +G DVND
Sbjct: 166 LFAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVND 225
Query: 1147 NSPKFYAFDEL-LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
++P FD E E+ +++ F + A + N I + + + D
Sbjct: 226 HTP---VFDHTSYETSLLESMPVNSRFF----ALAASDADVGPNGRISYAIVEGNDREED 278
Query: 1206 F-IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVAD-----VPDEVEM-------- 1251
F I + NG I R++ L S A L TV+D + D V++
Sbjct: 279 FSIDSRNGFI----RTRRSFDREALGGQSFLA-LEATVSDNGAVRLRDRVKIKVFITDVN 333
Query: 1252 SDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVID 1309
+ PVF+ Y ++I E + +LV + + E N + YYI N + F ID
Sbjct: 334 DNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAE---RFAID 390
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVR 1369
G + L R+ DRE +Y + V A L V +
Sbjct: 391 DSTGQITLARALDRETTASYRLTVVAHDASKQHRL----------------SASTTVTIE 434
Query: 1370 IKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
+ D ND++P+FT + AI T P G ++M+ +
Sbjct: 435 VLDENDDAPEFTQTLSQI--AIVETTPIGTELMRFR 468
Score = 63.7 bits (148), Expect = 4e-08
Identities = 53/173 (30%), Positives = 83/173 (47%), Gaps = 13/173 (7%)
Query: 218 IHAIDQDLGV-GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A+D+D+ + +I GN+ F +D +G + ++LD + T L +
Sbjct: 1130 VKAVDKDVRPQNNQFSFSIIGGNNDHSFKIDPQSGQIETARKLDRET-----VPTHKLLL 1184
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P +T V I + D+NDN P F+ +++EN P V+ + ATD D
Sbjct: 1185 GAIDTGTPPQTGTTVVRITVTDINDNGPTFDPKDTIGAVLENEPPNTVVMTLAATDPDLP 1244
Query: 337 ENG-EFTYQL--DDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKE 385
NG FTYQL K F+++ SG L TVR+ LDRE L + V ++
Sbjct: 1245 PNGAPFTYQLVGGRHKSLFTLERHSGVLKTVRS---LDREQTPQLELLVVVED 1294
Score = 63.7 bits (148), Expect = 4e-08
Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 9/160 (5%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G I T + LDRE +++ ++ + G G V I + D NDN P F+
Sbjct: 1162 QSGQIETARKLDRETVPTHKL-LLGAIDTGTPPQTGTTVVRITVTDINDNGPTFDPKDTI 1220
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFG-EGKEMFDVDENTGVVKFIGD 851
G ++EN T + + ATD D N A F Y L G K +F ++ ++GV+K +
Sbjct: 1221 GAVLENEPPNTVVMT---LAATDPDLPPNGAPFTYQLVGGRHKSLFTLERHSGVLKTVR- 1276
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DENDN 889
SLDRE+ +L +V D G + I + D+ND+
Sbjct: 1277 SLDREQTPQLELLVVVEDNGKPRKRTQHTITVNVLDQNDS 1316
Score = 61.3 bits (142), Expect = 2e-07
Identities = 50/159 (31%), Positives = 81/159 (50%), Gaps = 14/159 (8%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN-NPLKT-AQARVEIELLD 298
R F ++SV G++ + LD D + L + A L P ++ A A++ I + D
Sbjct: 1047 RNDFMVNSVTGAVSIRNPLDYDL-----IQVYQLNITAEDLGYKPKRSIAMAQIIISIQD 1101
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQL--DDPKGAFSID 355
ND PEF+ D Y S+ E P G V+ V A DKD + +N +F++ + + +F ID
Sbjct: 1102 GNDP-PEFQRDLYEASVSEGDPIGTKVIVVKAVDKDVRPQNNQFSFSIIGGNNDHSFKID 1160
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
P+SG + + LDRE + ++ + A +T P GT
Sbjct: 1161 PQSGQIETARK--LDRETVPTHKLLLGAIDTGTPPQTGT 1197
Score = 57.2 bits (132), Expect = 3e-06
Identities = 70/251 (27%), Positives = 107/251 (42%), Gaps = 24/251 (9%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
E++ Y ++ ++ + +++ D ND P +LYE S+ +GT + VKAVD D+
Sbjct: 1080 EDLGYKPKRSIAMAQIIISIQDGND--PPEFQRDLYEASVSEGDPIGTKVIVVKAVDKDV 1137
Query: 490 -GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPS 546
QN + + +N FKI+P +G + A E H L + A D P
Sbjct: 1138 RPQNNQFSFSIIGGNN---DHSFKIDPQSGQIETARKLDRETVPTHKLLLGAIDTGTPP- 1193
Query: 547 ERRYSLAVVTIEVTR-GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN 604
+ VV I VT G D D +GA E N T V + D N
Sbjct: 1194 --QTGTTVVRITVTDINDNGPTFDPKDTIGAVLE-----NEPPNTVVMTLAATDPDLPPN 1246
Query: 605 DV--SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-- 660
+Y L+ G + + F +E SGV+ V L R P + V +++N T
Sbjct: 1247 GAPFTYQLVGGRHKSL-FTLERHSGVLKTVRSLDREQTPQLEL-LVVVEDNGKPRKRTQH 1304
Query: 661 NATVHVVDVND 671
TV+V+D ND
Sbjct: 1305 TITVNVLDQND 1315
Score = 55.2 bits (127), Expect = 1e-05
Identities = 47/149 (31%), Positives = 69/149 (46%), Gaps = 18/149 (12%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L Y L+ G+ K F+L+ G L L LD + E +++ L+V + + +++ +
Sbjct: 700 LEYALLDGDAPKKFALERETGLLKLRDTLDRETE-----DSYRLKVSVT---DGIQSTET 751
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GENGEF----TY 343
+ I++ D NDN P F Y+ I EN GF V + ATD D NG Y
Sbjct: 752 TITIQITDTNDNPPVFAEPAYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVITVRAY 811
Query: 344 QLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
D P F +D SG +T VLD E
Sbjct: 812 DADTPP-RFRLDASSGEIT--TAAVLDCE 837
Score = 52.8 bits (121), Expect = 7e-05
Identities = 67/278 (24%), Positives = 112/278 (40%), Gaps = 29/278 (10%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F LD+ +G + LD + ++ F L Q S P T + I++ D+NDN
Sbjct: 819 FRLDASSGEITTAAVLDCE---DMPIYHFTLMAQDSSTTEPRATL-VNLTIDVQDVNDNS 874
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---------DDPKGAFSI 354
P F +++++ + + G V A D+D+G N Y + + F I
Sbjct: 875 PAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEI 934
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQPLETNAP 413
+ +G + T LDRE + + V A + P + G+ + L+ N
Sbjct: 935 NTDTG--EIYTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNV-------LDKNDN 985
Query: 414 LEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA 473
K T +F D+ K + D + + +T+ D NDN P F S Y F+ +
Sbjct: 986 PPKFTRLFSDEYILKVAAV---DGAWRTETPLTITIQDQNDNAPEFEHS-YYSFNFRELQ 1041
Query: 474 KVGTVIG--KVKAVDPDLGQNGMVLYDLQRTSNLTITS 509
K T V +V + + YDL + L IT+
Sbjct: 1042 KSVTFRNDFMVNSVTGAVSIRNPLDYDLIQVYQLNITA 1079
Score = 50.8 bits (116), Expect = 3e-04
Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 9/167 (5%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALD-GGNLNDNISVR---VFVKDVNDHFPVF 1045
F++N G V + L + ++LNI+A D G +I++ + ++D ND P F
Sbjct: 1050 FMVNSVTGAVSIRNPLDYDLIQVYQLNITAEDLGYKPKRSIAMAQIIISIQDGNDP-PEF 1108
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
++ Y +V E + V A D D QN ++ I + D F+I P +G +
Sbjct: 1109 QRDLYEASVSEGDPIGTKVIVVKAVDKDVRPQNNQFSFSIIGGNNDHSFKIDPQSGQIET 1168
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+LDRET + L + A D G D+NDN P F
Sbjct: 1169 ARKLDRETVPTHKLLLGAIDTG-TPPQTGTTVVRITVTDINDNGPTF 1214
Score = 50.0 bits (114), Expect = 5e-04
Identities = 56/192 (29%), Positives = 80/192 (41%), Gaps = 17/192 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E PIGT +I + A+D D +R + N + S F I+ + G
Sbjct: 1117 VSEGDPIGTKVIVVKAVDKD------VRPQNNQFSF------SIIGGNNDHSFKIDPQSG 1164
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ AR L E+ +L + A+D G VR+ V D+ND+ P F V
Sbjct: 1165 QIETARKLDRETVPTHKLLLGAIDTGTPPQTGTTVVRITVTDINDNGPTFDPKDTIGAVL 1224
Query: 1056 EAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + V+ + ATD D N A TY + F + +GVL LDRE
Sbjct: 1225 ENEPPNTVVMTLAATDPDLPPNGAPFTYQLVGGRHKSLFTLERHSGVLKTVRSLDREQTP 1284
Query: 1115 KYILTVVARDNG 1126
+ L VV DNG
Sbjct: 1285 QLELLVVVEDNG 1296
Score = 48.8 bits (111), Expect = 0.001
Identities = 65/253 (25%), Positives = 101/253 (39%), Gaps = 35/253 (13%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S ++T+ I D NDN P+F + Y + E G + +IA P IP G
Sbjct: 748 STETTITIQITDTNDNPPVFAEPAYSFDIPENAQRG--FHVGVIAATDPDNVIPPN--NG 803
Query: 138 LTIFKDIRAFDRDKP-----NTPNSDVHYSIVSGNDDG---HFAL----ESSHKP-VLLL 184
I +RA+D D P + + ++ + V +D HF L S+ +P L+
Sbjct: 804 YVI--TVRAYDADTPPRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLV 861
Query: 185 RKVLDY-DAGDKEFQLVIMASGKRIHKEIL---FPEPIHAIDQDLGVGATLRYELISGN- 239
+D D D + I F AID+D GV A L Y + +G
Sbjct: 862 NLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVI 921
Query: 240 ------DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
+F +++ G ++ LD + + L V+A P T A V
Sbjct: 922 EAATELSTPIFEINTDTGEIYTTTRLDRE-----DIAQYTLIVEAVDQGVPQLTGSATVL 976
Query: 294 IELLDLNDNLPEF 306
+ +LD NDN P+F
Sbjct: 977 VNVLDKNDNPPKF 989
>UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 868
Score = 159 bits (386), Expect = 5e-37
Identities = 176/704 (25%), Positives = 298/704 (42%), Gaps = 69/704 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ D DLG A L Y + G+ +F++ S +G L K+LD + ++ + +Q
Sbjct: 166 LQCTDSDLGTNAALSYSITDGDPNSVFTVSS-SGELTTVKQLDYET-----TQSYAITIQ 219
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + A + V++ + LN+ P F YN++I E P G
Sbjct: 220 ARDTSASQLMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATP--------------IGT 265
Query: 338 NGEFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
GE TY + P G+ F ID SG +T++ LD EA +S + V A + + S +
Sbjct: 266 TGELTYSM--PSGSPFYIDSLSGVITLKQG--LDYEAVTSYVLLVTATDGDASSPKSSMV 321
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDK--VGTKTENIEYYDEQLMSFVNVEVTLL-DAN 453
+ + E + V P+ VGT ++ D + ++ ++ D N
Sbjct: 322 NVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQFKMAIISDVN 381
Query: 454 DNNPVFVPSNLYEFSMKSNA---KVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
++ P F Y + +A +G I V A D D G +G + + + +
Sbjct: 382 EHTPQFTSGGSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAIIAGNE---EDK 438
Query: 511 FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F I+ +G + + E G + L V A D + S+ V ++V
Sbjct: 439 FLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDV-------ND 491
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGV 628
+ P+ + V N +G++V ++R D E + L + GV F +++ SGV
Sbjct: 492 NAPNCSVTAHVVEVAENASVGSTVLELRCEDVDE--GANSQLTYNITTGVDFTIDKSSGV 549
Query: 629 ITVVDDLSRYNRPMYDFEAVALQ----ENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+ V L R R +Y+ E + V T+ V D ND V + ++
Sbjct: 550 VAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTT 609
Query: 685 IFHVKENSA-GAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
I EN A GA++ ++ T+ I N T ++ D +I + + T
Sbjct: 610 I---PENMASGASVARVATTDRDIGINANHTYSI-----TGGDGLGKFSIVQSTGVITAL 661
Query: 743 P-LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
P LD E + Y +++ A ++G + V I++ D NDN PVF Y I E +
Sbjct: 662 PGLDYETKYTYYLSITAR-DRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATS 720
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
GT++ + ATD D G NA Y++ G+ K F V+ +TG+++ I +LDRE
Sbjct: 721 AGTDVIP---VHATDVDTGINAEITYSIVGGDAKNQFSVN-STGMIRTIA-TLDREDIAS 775
Query: 861 YKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
Y L + A D G + + + I D NDN F+Q +++V
Sbjct: 776 YTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARV 819
Score = 147 bits (355), Expect = 3e-33
Identities = 223/910 (24%), Positives = 356/910 (39%), Gaps = 124/910 (13%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
N+ P F+P+N YE S+ + VG + V A D D G G + L++T F
Sbjct: 37 NEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDADAGSQGEDAFIF-----LSVTGNFN 91
Query: 513 INPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
++ G VS+A + E ++L + +D + + S+ V I V +
Sbjct: 92 VS-TAGVVSLATALDYESTRLYSLVLSVTDSGLSTKSTQISVKVTVIAVNEFS------- 143
Query: 571 PDFM-GAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSG 627
P F G Y +N +GTS+ Q++ D+ + +SY + G V F V SG
Sbjct: 144 PVFTSGGTYAV---TNTTVGTSITQLQCTDSDLGTNAALSYSITDGDPNSV-FTVSS-SG 198
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
+T V L Y A +A+ L V++ V V +N+ + ++ I
Sbjct: 199 ELTTVKQLDYETTQSYAITIQARDTSASQLMAVSHVDVIVQALNEYTPSFSQSEYNVTI- 257
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
S IG T Y +G+ ++ D ++ G I ++ LD
Sbjct: 258 -----SEATPIG----TTGELTYSMPSGSPFYI--------DSLS----GVITLKQGLDY 296
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E Y + V A + + VT+ ++DENDN P F A Y I EN+ +GT I
Sbjct: 297 EAVTSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEPTFTPAVYSVVIPENTTVGTSI 356
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ TD+D GTN F + + E + G + + I ++ V
Sbjct: 357 LS---LTCTDSDSGTNGQFKMAIISDVNEHTPQFTSGGSYTAVIAEDAPDTAIGVTIATV 413
Query: 867 ARDTGGLSSEAEL--IIMIGDENDN------------KPEFNQIEENSKV-----RIHRE 907
A S+ + I+ G+E D K ++ S + R H
Sbjct: 414 AATDADHGSDGAISFAIIAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGS 473
Query: 908 TKL--NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
N + T+++V N A + + + EN +G+T+++L D+D G N Q
Sbjct: 474 PNKSSNASVDVTVVDV---NDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQ 530
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG 1023
+ Y + V F I++ G V V SL E+ + LNI+ D G
Sbjct: 531 LTYNITTGVD----------------FTIDKSSGVVAVGSSLDRETRDLYELNITVRDRG 574
Query: 1024 NLNDN-----ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
N + + + V D ND+ PVF + Y + E + + +V TD D G NA
Sbjct: 575 NTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINA 634
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
N TY I D F I TGV++ LD ET+ Y L++ ARD G
Sbjct: 635 NHTYSITGGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRG-SPQLYAVAGVR 693
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE--NAPIGTTV 1196
D NDN P F L +S +IPV+ ++ NA I ++
Sbjct: 694 IFLSDTNDNKPVFSPTLYL--------TSISEATSAGTDVIPVHATDVDTGINAEITYSI 745
Query: 1197 AKVFANDTDFIGNGNGLI----------LYSLPQRKNQQNLGLPSLSSTAILMVTVADVP 1246
A + F N G+I + S + G+P + T + VT+ DV
Sbjct: 746 VGGDAKN-QFSVNSTGMIRTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVN 804
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTF 1306
D + + F +R E + V +S + + +N ++ Y I + N TD
Sbjct: 805 DNAAVFSQSAFSARVLE---DAPVGFRFMNISASDADSGDNARLTYSIQSGN-TD--NVV 858
Query: 1307 VIDPRNGTLY 1316
I+ G LY
Sbjct: 859 AIESATGALY 868
Score = 113 bits (271), Expect = 5e-23
Identities = 109/416 (26%), Positives = 186/416 (44%), Gaps = 36/416 (8%)
Query: 441 SFVNVEVTLLDANDNNP-VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
S +V+VT++D NDN P V +++ E + NA VG+ + +++ D D G N + Y
Sbjct: 478 SNASVDVTVVDVNDNAPNCSVTAHVVEVA--ENASVGSTVLELRCEDVDEGANSQLTY-- 533
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTI 557
N+T F I+ ++G V+V S E R + L + D+ ERR ++ +TI
Sbjct: 534 ----NITTGVDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTI 589
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE-- 615
EVT + + P P F Y + N+ G SV ++ D D+ + H Y
Sbjct: 590 EVT--DENDNP--PVFTQEIYTTTIPENMASGASVARVATTD----RDIGINANHTYSIT 641
Query: 616 --EGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
+G+ F++ + +GVIT + L + Y A + L V + + D ND
Sbjct: 642 GGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTND 701
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ V SP ++ + A +A + + + + + + I D + +
Sbjct: 702 NKPVF-----SPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGG-DAKNQFS 755
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G I T LDRE Y + V A ++GV VT+ I D NDN VF +
Sbjct: 756 VNSTGMIRTIATLDREDIASYTLLVQAS-DRGVPPQTETVHVTVTILDVNDNAAVFSQSA 814
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVV 846
+ ++E++ +G + N I A+DAD G NA Y++ G + ++ TG +
Sbjct: 815 FSARVLEDAPVG--FRFMN-ISASDADSGDNARLTYSIQSGNTDNVVAIESATGAL 867
Score = 81.8 bits (193), Expect = 1e-13
Identities = 68/278 (24%), Positives = 116/278 (41%), Gaps = 20/278 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLTIPLT 133
+A + +T+ + D NDN P+F Y T+ E +G I + T +T
Sbjct: 582 AAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSIT 641
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSD-----VHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
GL F +++ P D +Y ++ D G L + + L
Sbjct: 642 GGDGLGKFSIVQSTGVITA-LPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTN 700
Query: 189 DYD-AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D L ++ +++ P+HA D D G+ A + Y ++ G+ + FS
Sbjct: 701 DNKPVFSPTLYLTSISEATSAGTDVI---PVHATDVDTGINAEITYSIVGGDAKNQFS-- 755
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
VN + + LD E ++ L VQAS P +T V + +LD+NDN F
Sbjct: 756 -VNSTGMIRTIATLDRE---DIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFS 811
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
++ ++E+ P GF + + A+D D G+N TY +
Sbjct: 812 QSAFSARVLEDAPVGFRFMNISASDADSGDNARLTYSI 849
Score = 46.4 bits (105), Expect = 0.006
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMA 330
+ L +QAS P K + I++ +N+ P F + Y +S+ E+L G V+ V A
Sbjct: 9 YTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVILVTA 68
Query: 331 TDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
+D D G GE + G F++ V T LD E+ + + ++ S
Sbjct: 69 SDADAGSQGEDAFIFLSVTGNFNVSTAG---VVSLATALDYESTRLYSLVLSVTDSGLST 125
Query: 391 VGTFADSQ--RIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
T + IA P+ T+ T V VGT ++ D L + + +
Sbjct: 126 KSTQISVKVTVIAVNEFSPVFTSG---GTYAVTNTTVGTSITQLQCTDSDLGTNAALSYS 182
Query: 449 LLDANDNNPVFVPSNLYEFS 468
+ D D N VF S+ E +
Sbjct: 183 ITD-GDPNSVFTVSSSGELT 201
Score = 36.3 bits (80), Expect = 6.5
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 47 DSPQNVVKFRLGCDFDEGDDLVRI-----GAGLNQISAYLSVTVYIEDVNDNVPIFLDTP 101
DS V+ + G D++ V + G + S+ ++VTV ++D NDN P F
Sbjct: 282 DSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEPTFTPAV 341
Query: 102 YHVTVDELTPTG 113
Y V + E T G
Sbjct: 342 YSVVIPENTTVG 353
Score = 35.9 bits (79), Expect = 8.6
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G Q+ A V +++ D NDN P+F T Y ++ E T G
Sbjct: 682 GSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAG 722
>UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 850
Score = 159 bits (385), Expect = 7e-37
Identities = 233/916 (25%), Positives = 363/916 (39%), Gaps = 124/916 (13%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ--RTSNLTITSPFKIN 514
PVF P++ + ++ G +I VKA D D G NG V Y + + S F ++
Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLD 60
Query: 515 PNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
PNTG + A + LE + + A+ +S A + + G + P F
Sbjct: 61 PNTGMIKTARN--LERQQTFSYNLTIGAADHGLPSFS-ATTRVSIVVGDLNDNN--PVFN 115
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLLHGYEEGVPFAVEERS--GVIT 630
Y V N +GTS+ + DA QN V+Y + G G+ AV + S G I
Sbjct: 116 PTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIE 175
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLS--IVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
V +L R Y+ A +S + A V ++D ND + K +H+ +
Sbjct: 176 VAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDN---VPKFSHARYTGSI 232
Query: 689 KENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ----KP 743
+ENS Q+ + M++ +VR+ + N D G I T+
Sbjct: 233 QENSGPGVPVQMASSIMATDRDIESNADVRYRL-NGSDSIQFAVNPRTGVITTRVSPPPS 291
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LD E+ Y VIA G + +V I++ D NDN P F ++ + I E + IG
Sbjct: 292 LDHERTTNYTFHVIAADQAGT-GHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIG 350
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+ + A D D G N +++ + F++ + GVV
Sbjct: 351 QSVAR---VTANDPDSGLNGRIFFSINSGSEGKFEIGRSDGVV----------------- 390
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
R +G L EA+ + ++ + + ++ E V + + + T FT KP
Sbjct: 391 ----RVSGSLDREAKAVYVL-NVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFT----KP 441
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
A +VD + E + +G+ I+ A D D G N I Y + P
Sbjct: 442 ----AFNVD-------VSEGVAVGSVIVNATATDPDQGSNAAITYSMSY-----PG---- 481
Query: 984 DALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDH 1041
F IN G V + R L E++ + + A DGG L N++V V + D ND+
Sbjct: 482 --------FAINSNTGSVTITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDN 533
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
P F Y +V + ++ V+A D D G N ++TY I LPF I P TG
Sbjct: 534 SPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAI----LILPFIIVPDTGN 589
Query: 1102 LSVNGELDRETED-----KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
++ + +LDRE + Y+L + D+G D NDN P
Sbjct: 590 INTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVT-DFNDNQP------- 641
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLI- 1214
++ E N + + A E++ + + D F I G I
Sbjct: 642 --QFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTGQIR 699
Query: 1215 LYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
L R+ ++N G P LSS A + V V DV D + PVF SR YE
Sbjct: 700 LQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVND-----NPPVFTSRVYERT 754
Query: 1266 IEE-NVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+ E N A +V +N T+ N + Y I++ F I+ G + +
Sbjct: 755 MSEGNAAAGEFVVQVNATDADVERNGHVTYTIMH----GALGMFTINETTGVIRTQGVLN 810
Query: 1323 REVKDTYEVIVRAERQ 1338
RE KD Y +IV A Q
Sbjct: 811 RESKDFYTLIVMARDQ 826
Score = 155 bits (376), Expect = 9e-36
Identities = 148/483 (30%), Positives = 212/483 (43%), Gaps = 40/483 (8%)
Query: 436 DEQLMSF---VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
D L SF V + + D NDNNPVF P+N Y ++ N+ VGT + V A D D GQN
Sbjct: 88 DHGLPSFSATTRVSIVVGDLNDNNPVFNPTN-YSTTVFENSPVGTSLLDVTATDADSGQN 146
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRY 550
V Y + + + N GT+ VA + E + L + A+D S
Sbjct: 147 AYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAI 206
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV---GQIRVNDA-FEQN-D 605
++A+V I ++P F A Y + N G G V I D E N D
Sbjct: 207 AIALVRI------LDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNAD 260
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITV----VDDLSRYNRPMYDFEAVAL-QENANLSIVT 660
V Y L +G + + FAV R+GVIT L Y F +A Q +
Sbjct: 261 VRYRL-NG-SDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLA 318
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFL 719
+HV+D ND + + I S A+IGQ ++ +G G + F
Sbjct: 319 EVVIHVLDANDNTPRFIPSSIQSTI------SEAASIGQSVARVTANDPDSGLNGRIFFS 372
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
I + + +I DG + LDRE + VY + V A + G VT+ ++D
Sbjct: 373 INSGSEGKFEIG-RSDGVVRVSGSLDREAKAVYVLNVSA-IDGSYSPREGYGTVTVTLQD 430
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
NDN P F + + E +G+ I ATD D+G+NA Y++ G F +
Sbjct: 431 VNDNTPKFTKPAFNVDVSEGVAVGSVIVNAT---ATDPDQGSNAAITYSMSYPG---FAI 484
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ NTG V I LDRE K Y ++ ARD GGL S + + IGDENDN P+F ++
Sbjct: 485 NSNTGSVT-ITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQ 543
Query: 900 SKV 902
+ V
Sbjct: 544 TDV 546
Score = 149 bits (362), Expect = 4e-34
Identities = 135/505 (26%), Positives = 224/505 (44%), Gaps = 50/505 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + +LDANDN P F+PS++ + ++ A +G + +V A DPD G NG + + +
Sbjct: 316 SLAEVVIHVLDANDNTPRFIPSSI-QSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN 374
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
S F+I + G V V+ S E + + L V A D +P E ++ V +
Sbjct: 375 SGSE----GKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQD 430
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V T P F + +V G +VG + VN D + Y
Sbjct: 431 VNDNT-------PKFTKPAFNV----DVSEGVAVGSVIVNATATDPDQGSNAAITYSMSY 479
Query: 619 P-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
P FA+ +G +T+ L R + Y F V ++ L V + D ND
Sbjct: 480 PGFAINSNTGSVTITRPLDRETKQAYSF-TVHARDGGGLESNVAVNVEIGDENDN----- 533
Query: 678 KGAHSPIIFHVKENSAGAAIGQI-FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
P + + + +G I N G+V + I + I + + G
Sbjct: 534 -SPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIL----ILPFIIVPDTG 588
Query: 737 TIFTQKPLDREKRDVYRMTV----IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
I T LDRE++ +Y + ++ + GV + I + D NDN P F + Y
Sbjct: 589 NINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEY 648
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
++EN +GT++ M + A D D G N+ MY+L G G +F ++ +TG ++ + +
Sbjct: 649 SATVLENMPVGTKVTM---VTARDEDSGINSQIMYSLTG-GDGVFSIEPSTGQIR-LQKA 703
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
++RE K Y +++ A D G LSS+A++ + + D NDN P F S+V ++
Sbjct: 704 INREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVF-----TSRVYERTMSEG 758
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLG 935
N AG +++V N DV++ G
Sbjct: 759 NAAAGEFVVQV---NATDADVERNG 780
Score = 118 bits (285), Expect = 9e-25
Identities = 120/458 (26%), Positives = 190/458 (41%), Gaps = 43/458 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VTL D NDN P F + + VG+VI A DPD G N + Y +
Sbjct: 424 VTVTLQDVNDNTPKFTKP-AFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMSYPG- 481
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F IN NTG+V++ E + A + E S V +E+
Sbjct: 482 ------FAINSNTGSVTITRPLDRETKQAYSFTVHARDGGGLE---SNVAVNVEI----- 527
Query: 565 GNKPD-IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFA 621
G++ D P F Y+ V +GT V + D N+ V+Y +L +PF
Sbjct: 528 GDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAILI-----LPFI 582
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT------VHVVDVNDERGV 675
+ +G I L R + +Y L + VT T + V D ND +
Sbjct: 583 IVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQ 642
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ +S + ++ G + + + S + + + + V
Sbjct: 643 FNQSEYSATV--LENMPVGTKVTMVTARDEDSGINS---QIMYSLTGGDGVFS--IEPST 695
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I QK ++RE ++ Y +T+ A ++G + +V +++ D NDNPPVF YE
Sbjct: 696 GQIRLQKAINREAKENYHVTITAS-DRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERT 754
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E + E + + ATDAD N YT+ MF ++E TGV++ G L+R
Sbjct: 755 MSEGNAAAGEFVVQ--VNATDADVERNGHVTYTIMHGALGMFTINETTGVIRTQG-VLNR 811
Query: 856 EKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKP 891
E K Y L ++ARD G + + + + D+NDN P
Sbjct: 812 ESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTP 849
Score = 104 bits (250), Expect = 2e-20
Identities = 131/460 (28%), Positives = 198/460 (43%), Gaps = 71/460 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E IG ++ ++ A D DSGLNG+I + NS E K F I G
Sbjct: 343 ISEAASIGQSVARVTANDPDSGLNGRIFFSINS------------GSEGK--FEIGRSDG 388
Query: 1000 HVIVARSLPPESE--FRLNISALDGG-NLNDNI-SVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V V+ SL E++ + LN+SA+DG + + +V V ++DVND+ P F K +N +V
Sbjct: 389 VVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVS 448
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E V+ ATD D G NA +TY S + F I+ TG +++ LDRET+
Sbjct: 449 EGVAVGSVIVNATATDPDQGSNAAITY----SMSYPGFAINSNTGSVTITRPLDRETKQA 504
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y TV ARD G D NDNSP+F ++++ D
Sbjct: 505 YSFTVHARDGG---GLESNVAVNVEIGDENDNSPQF----PTVQYQTDVIDRTPVGTI-- 555
Query: 1176 VMMIPVYKATIEENAPIGTTV---AKVFANDTDFIGNGNGL-----ILYSLPQ---RKNQ 1224
V+ + + N + + + DT I + L LY+L +
Sbjct: 556 VLAVNAEDRDVGNNGHVTYAILILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSV 615
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLT 1282
+ G+ +S A+L ++V D D ++P F Y + EN V V +V+
Sbjct: 616 TDHGVTQFTSFALLNISVTDFND-----NQPQFNQSEYSATVLENMPVGTKVTMVTARDE 670
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
+ N ++ Y + + F I+P G + L ++ +RE K+ Y V + A R
Sbjct: 671 DSGINSQIMYSLTGGDG-----VFSIEPSTGQIRLQKAINREAKENYHVTITAS----DR 721
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
P VL D KV V + DVNDN P FT+
Sbjct: 722 GTP---------VLSS----DAKVHVHVLDVNDNPPVFTS 748
Score = 90.2 bits (214), Expect = 4e-16
Identities = 93/353 (26%), Positives = 150/353 (42%), Gaps = 24/353 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V V + D NDN+P F P+ Y+ + VGT++ V A D D+G NG V Y
Sbjct: 517 LESNVAVNVEIGDENDNSPQF-PTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYA 575
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + + IN ++ +S + L + +D S A++ I
Sbjct: 576 ILILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFT---SFALLNIS 632
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEE 616
VT P F + Y V N+ +GT V + R D+ + + Y L G +
Sbjct: 633 VTDFNDNQ----PQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGG--D 686
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGV 675
GV F++E +G I + ++R + Y A LS VHV+DVND V
Sbjct: 687 GV-FSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPV 745
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ + + AA G+ + N + G+V + I + I E
Sbjct: 746 FTSRVYERTM-----SEGNAAAGEFVVQVNATDADVERNGHVTYTIMH--GALGMFTINE 798
Query: 735 D-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G I TQ L+RE +D Y + V+A ++G + + +++ D+NDN P+
Sbjct: 799 TTGVIRTQGVLNRESKDFYTLIVMAR-DQGAVPYMDFGTIDVHVIDKNDNTPI 850
Score = 89.8 bits (213), Expect = 5e-16
Identities = 69/213 (32%), Positives = 103/213 (48%), Gaps = 22/213 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN+P+GT + + A D DSG+N QI Y S D + F I G +
Sbjct: 654 ENMPVGTKVTMVTARDEDSGINSQIMY----------SLTGGDGV-----FSIEPSTGQI 698
Query: 1002 IVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ +++ E++ + + I+A D G L+ + V V V DVND+ PVF Y + E
Sbjct: 699 RLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEG 758
Query: 1058 QYTR-RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ +V+ATDAD +N ++TY I + F I+ TGV+ G L+RE++D Y
Sbjct: 759 NAAAGEFVVQVNATDADVERNGHVTYTIMHGALGM-FTINETTGVIRTQGVLNRESKDFY 817
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
L V+ARD G D NDN+P
Sbjct: 818 TLIVMARDQG-AVPYMDFGTIDVHVIDKNDNTP 849
Score = 86.2 bits (204), Expect = 6e-15
Identities = 81/323 (25%), Positives = 141/323 (43%), Gaps = 20/323 (6%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP------SLTIPLT 133
Y +VTV ++DVNDN P F ++V V E G + I P ++T ++
Sbjct: 421 YGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVG--SVIVNATATDPDQGSNAAITYSMS 478
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
P G I + + +P + YS DG LES+ V + ++ D +
Sbjct: 479 YP-GFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG-GLESN---VAVNVEIGDENDN 533
Query: 194 DKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
+F V + + ++A D+D+G + Y ++ F + G+
Sbjct: 534 SPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAILI----LPFIIVPDTGN 589
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ +LD + + +VL + + T+ A + I + D NDN P+F Y+
Sbjct: 590 INTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYS 649
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+++EN+P G V V A D+D G N + Y L G FSI+P +G +R Q ++RE
Sbjct: 650 ATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTG--QIRLQKAINRE 707
Query: 373 AHSSLRMKVYAKETNPSVVGTFA 395
A + + + A + V+ + A
Sbjct: 708 AKENYHVTITASDRGTPVLSSDA 730
Score = 83.4 bits (197), Expect = 4e-14
Identities = 88/330 (26%), Positives = 146/330 (44%), Gaps = 29/330 (8%)
Query: 69 RIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGP 126
R G GL + ++V V I D NDN P F Y V + TP G +G
Sbjct: 512 RDGGGLE---SNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGN 568
Query: 127 S-------LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSH 178
+ L +P + DR++ + VHY + +S D G S
Sbjct: 569 NGHVTYAILILPFIIVPDTGNINTSSKLDREQQSLYTL-VHYVLNLSVTDHGVTQFTSF- 626
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELIS 237
LL V D++ +F ++ + + + A D+D G+ + + Y L
Sbjct: 627 --ALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTG 684
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
G+ +FS++ G + L+K ++ +A+ N + + + AS P+ ++ A+V + +L
Sbjct: 685 GDG--VFSIEPSTGQIRLQKAINREAKEN-----YHVTITASDRGTPVLSSDAKVHVHVL 737
Query: 298 DLNDNLPEFEVDFYNISIVE-NLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSID 355
D+NDN P F Y ++ E N G V+QV ATD D NG TY + G F+I+
Sbjct: 738 DVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTIMHGALGMFTIN 797
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G +R Q VL+RE+ + V A++
Sbjct: 798 ETTG--VIRTQGVLNRESKDFYTLIVMARD 825
Score = 74.1 bits (174), Expect = 3e-11
Identities = 83/326 (25%), Positives = 134/326 (41%), Gaps = 20/326 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
GL SA V++ + D+NDN P+F T Y TV E +P G A G + +
Sbjct: 90 GLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYV 149
Query: 131 PLTVPRGLT--IFKDIRAFDR----DKPNTPNSDVH--YSIVSGNDDGHFALESSHKPVL 182
+V G + +F+ + + + +V+ Y++ DG + + +
Sbjct: 150 TYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIA 209
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHK----EILFPEPIHAIDQDLGVGATLRYELISG 238
L+R +LD + +F + + + I A D+D+ A +RY L +G
Sbjct: 210 LVR-ILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYRL-NG 267
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+D F+++ G + +H N + V A+ + A V I +LD
Sbjct: 268 SDSIQFAVNPRTGVITTRVSPPPSLDHERTTN-YTFHVIAADQAGTGHESLAEVVIHVLD 326
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-PKGAFSIDPR 357
NDN P F +I E G SV +V A D D G NG + ++ +G F I
Sbjct: 327 ANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGKFEIGRS 386
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYA 383
G VR LDREA + + V A
Sbjct: 387 DG--VVRVSGSLDREAKAVYVLNVSA 410
Score = 72.5 bits (170), Expect = 8e-11
Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 10/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + + + SG++ K F + +G + + LD +A+ +VL V
Sbjct: 356 VTANDPDSGLNGRIFFSINSGSEGK-FEIGRSDGVVRVSGSLDREAKA-----VYVLNVS 409
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + V + L D+NDN P+F +N+ + E + G ++ ATD DQG
Sbjct: 410 AIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGS 469
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N TY + P F+I+ +G +T+ LDRE + V+A++
Sbjct: 470 NAAITYSMSYP--GFAINSNTGSVTITRP--LDRETKQAYSFTVHARD 513
Score = 70.5 bits (165), Expect = 3e-10
Identities = 69/242 (28%), Positives = 110/242 (45%), Gaps = 25/242 (10%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q SF + +++ D NDN P F S Y ++ N VGT + V A D D G N ++Y
Sbjct: 622 QFTSFALLNISVTDFNDNQPQFNQSE-YSATVLENMPVGTKVTMVTARDEDSGINSQIMY 680
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQ--PANPSERRYSLA 553
L + F I P+TG + + ++ E + + + + ASD+ P S+ + +
Sbjct: 681 SLTGGDGV-----FSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVH 735
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVG-SNVGIGTSVGQIRVNDA-FEQN-DVSYDL 610
V+ + + P P F YE + N G V Q+ DA E+N V+Y +
Sbjct: 736 VLDV-------NDNP--PVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTI 786
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
+HG G+ F + E +GVI L+R ++ Y +A + A VHV+D
Sbjct: 787 MHG-ALGM-FTINETTGVIRTQGVLNRESKDFYTLIVMARDQGAVPYMDFGTIDVHVIDK 844
Query: 670 ND 671
ND
Sbjct: 845 ND 846
Score = 70.1 bits (164), Expect = 4e-10
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 13/176 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGN-----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D G + Y ++ GN F+LD G + + L+ Q ++
Sbjct: 26 VKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLDPNTGMIKTARNLERQ-----QTFSY 80
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L + A+ P +A RV I + DLNDN P F Y+ ++ EN P G S+L V ATD
Sbjct: 81 NLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATD 140
Query: 333 KDQGENGEFTYQL--DDPKGAF-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G+N TY + D G F ++ S T+ LDRE + + + A +
Sbjct: 141 ADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATD 196
Score = 41.1 bits (92), Expect = 0.23
Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 23/157 (14%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE--HY 1285
GLPS S+T + + V D+ D + PVF Y + EN L+ + T+
Sbjct: 90 GLPSFSATTRVSIVVGDLND-----NNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSG 144
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+N + Y + + + R +GT+ + + DREV D Y + + A
Sbjct: 145 QNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGG------ 198
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
P++ + +VRI D NDN PKF++
Sbjct: 199 ---VPISRTAI-------AIALVRILDRNDNVPKFSH 225
Score = 37.1 bits (82), Expect = 3.7
Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 18/168 (10%)
Query: 304 PEFEVDFYNISIVE-NLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPK--GAFSID 355
P F YN + E + G + V ATD D G NG+ Y + DP+ F++D
Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLD 60
Query: 356 PRSGWL-TVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQPLETNAP 413
P +G + T RN L+R+ S + + A + PS T S + N P
Sbjct: 61 PNTGMIKTARN---LERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFN-P 116
Query: 414 LEKTTYVFPDK-VGTKTENIEYYDEQLMSFVNVEVTL-LDANDNNPVF 459
+T VF + VGT ++ D S N VT + A D++ +F
Sbjct: 117 TNYSTTVFENSPVGTSLLDVTATDAD--SGQNAYVTYSVTAGDSHGLF 162
Score = 36.3 bits (80), Expect = 6.5
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 1437 TSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTV 1473
+S ATD DI NAD+RY++ + +FA++P +G +
Sbjct: 246 SSIMATDRDIESNADVRYRLNGSDSIQFAVNPRTGVI 282
>UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1852
Score = 159 bits (385), Expect = 7e-37
Identities = 150/507 (29%), Positives = 234/507 (46%), Gaps = 53/507 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ + D NDN PVF PS Y+ +K N GT +V A D D NG +++ + + ++
Sbjct: 364 INVNDINDNPPVFSPS-AYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDG 419
Query: 507 ITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ F I+ +TG +S+A+SP E R+ L V+A D+ +Y A VTI + +
Sbjct: 420 V---FTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPV---KYDTAQVTIFI----E 469
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAV 622
P F + Y + + IG++V + D + + + Y L+ G +G F +
Sbjct: 470 DVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGA-FNI 528
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAH 681
+ SG I V +L R P Y + A + + S T T+ + D+ND +
Sbjct: 529 DANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIF----Q 584
Query: 682 SPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
P +F V E+S+ G IGQ+ T+ + G+VR+ +++ DV G I
Sbjct: 585 GPYVFRVSESSSPGHQIGQVAATDADD---SSNGDVRYALSDNTDVFS--INTSTGLITL 639
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
+ LD EK+ Y +TV A+ + G S + + V + ++D NDNPP F + Y + EN
Sbjct: 640 KTQLDYEKKTQYMVTVTAK-DGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENL 698
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKI 859
G + + ATDAD G N Y++ + M F +D TG + LDRE
Sbjct: 699 AAGVAV---CYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEIT-TRVPLDRETIA 754
Query: 860 MYKLSLVARDTGGL---SSEAELIIMIGDENDNKPEFN-----QIEENSK--VRI----- 904
Y L++ A D G L + + I I DENDN+P F I E+S R+
Sbjct: 755 SYSLTINA-DDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTA 813
Query: 905 -HRETKLNGTAGFTIIEVKPKNKFALD 930
R+ NG + II N F LD
Sbjct: 814 TDRDIGPNGAVTYAIISGNQGNSFQLD 840
Score = 149 bits (361), Expect = 6e-34
Identities = 133/505 (26%), Positives = 228/505 (45%), Gaps = 43/505 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N + +LD NDN PVF P + Y S+ N +G + KV A D D G+N V Y+L
Sbjct: 1084 NATIRVLDVNDNAPVFNPGS-YAKSLHENLPIGQTVAKVTATDRDEGENAKVTYEL---- 1138
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
++ TS F++NP TG V+ E + ++L V A D PS+ ++A +T+ +
Sbjct: 1139 SVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDH-GKPSQS--AVAAITLTIND 1195
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP 619
+ P F + Y V N G+++ ++ +D A V+Y ++ G G
Sbjct: 1196 LNDNS----PQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISG-NHGNA 1250
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVNDERGVLLK 678
F ++ +G ITVV + R Y+ A + T + V D ND +
Sbjct: 1251 FRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFAS 1310
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
S + + E G +IG ++ G+ F + D + A +G +
Sbjct: 1311 NETS---YGIDE---GVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVL 1364
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+K ++RE Y +T+ A ++G ++T+ + D NDNPPVF +Y G + E
Sbjct: 1365 TVKKEINRETVPTYTLTIRAS-DRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRE 1423
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREK 857
NS T + + A D+D G NA+ Y++ G ++ F ++ +GV+ LD E+
Sbjct: 1424 NSAQSTSVL---TVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVI-MTTTPLDFEE 1479
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN------ 911
K Y L + A D+ +++ + I + + ND P F Q + VR + T +
Sbjct: 1480 KSQYGLEVTATDS-KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSA 1538
Query: 912 ------GTAGFTIIEVKPKNKFALD 930
G+ ++I+ K +KF++D
Sbjct: 1539 SDRDSFGSLSYSIVGGKDSDKFSID 1563
Score = 142 bits (344), Expect = 7e-32
Identities = 145/508 (28%), Positives = 227/508 (44%), Gaps = 53/508 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+ D NDN+P+F SN + + +G+ + V A D D G N V Y + R
Sbjct: 1294 VAITVADENDNSPIFA-SNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGD- 1351
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
TS F IN G ++V + E + L + ASD+ + L VV +V
Sbjct: 1352 ---TSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVN-- 1406
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDV-SYDLLHGYEEGVPF 620
+ P P F Y V N TSV + +D+ N V Y ++ G +E F
Sbjct: 1407 ---DNP--PVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEK-RF 1460
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+ SGVI L + Y E A ++ + TN T+ V+++ND +
Sbjct: 1461 KINSTSGVIMTTTPLDFEEKSQYGLEVTAT--DSKYTAKTNVTIRVINLNDITPAFTQQN 1518
Query: 681 HSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTI 738
++ V+ENS ++ ++ ++ S G++ + I +D +D +I + G I
Sbjct: 1519 YTA---SVRENSPTSTSVVKVSASDRDSF-----GSLSYSIVGGKD-SDKFSIDQRSGII 1569
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LDRE +Y + V + G + + VTI I DENDN P F+ ++Y I+E
Sbjct: 1570 STADVLDRELVSLYAIQVRVT-DAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILE 1628
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
NS + ATDADEGTNA Y L + F + ++GV+ + LDRE K
Sbjct: 1629 NS---APSSFSFKLAATDADEGTNARITYNL--SRNDAFMIGASSGVIT-LAQPLDRENK 1682
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN------QIEENSKVRIH----- 905
Y L++ ARD G +S + + + D ND++P N + EN H
Sbjct: 1683 STYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRIL 1742
Query: 906 ---RETKLNGTAGFTIIEVKPKNKFALD 930
+T LN F+++ + K+ F LD
Sbjct: 1743 ASDADTGLNAELTFSLLSNEHKSVFTLD 1770
Score = 141 bits (342), Expect = 1e-31
Identities = 143/508 (28%), Positives = 215/508 (42%), Gaps = 45/508 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + L D NDN+P+F Y F + ++ G IG+V A D D NG V Y L
Sbjct: 565 SSTRVTIALQDINDNSPIF--QGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALS 622
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
T F IN +TG +++ E + V + + + R SL VV + V
Sbjct: 623 DN-----TDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGG-TPSRSSLTVVKVMV- 675
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV 618
+ P P F + Y VG N+ G +V + DA +SY +L G E +
Sbjct: 676 -DDVNDNP--PQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSG-NENM 731
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLL 677
FA++ +G IT L R Y A + T + + D ND +
Sbjct: 732 AFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFT 791
Query: 678 KGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
P F++ E+S G +GQ+ T+ I NG + NQ + G
Sbjct: 792 ----GPSRFNISEDSPTGTRVGQLTATD-RDIGPNGAVTYAIISGNQGNSFQ--LDPRSG 844
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ + LDRE Y + V A + G + + + + D NDN P FE + + G I
Sbjct: 845 ILSVRSTLDRETIPSYTLVVKAS-DAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEI 903
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E++ + + + +K D DEG+N +L GEG + F +D +TG V LD E
Sbjct: 904 REDASVHSTVLQ---VKVEDKDEGSNGAITLSLSGEGSDNFTID-STGFV-LSKTPLDYE 958
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF------NQIEENSKVRIHRET 908
Y+L++ ARD G S+ A++ I I + NDN P F I E+ + H
Sbjct: 959 TTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTH-VV 1017
Query: 909 KLNGTAG------FTIIEVKPKNKFALD 930
KLN T F I+E + F +D
Sbjct: 1018 KLNATDSDGTPLTFDIVEGNAGSSFKID 1045
Score = 141 bits (341), Expect = 2e-31
Identities = 125/459 (27%), Positives = 215/459 (46%), Gaps = 38/459 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL--QR 501
++ V++LD NDN P F S L+ ++ +A V + + +VK D D G NG + L +
Sbjct: 879 SIHVSVLDVNDNAPRFEKS-LFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEG 937
Query: 502 TSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ N TI S TG V ++++P+ + L V A D +PS+ + +TI
Sbjct: 938 SDNFTIDS-------TGFV-LSKTPLDYETTAAYQLTVTARDG-GSPSKSATAQVKITII 988
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
++P F+ + +V I T V ++ D+ + +++D++ G G
Sbjct: 989 NVND------NVPSFVSPAQVTSIPEDVAINTHVVKLNATDS-DGTPLTFDIVEG-NAGS 1040
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLL 677
F +++ SG+I+V L R Y A + + S+ NAT+ V+DVND V
Sbjct: 1041 SFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFN 1100
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
G+++ + + G + ++ T+ V + ++ ++ A G
Sbjct: 1101 PGSYAKSLH--ENLPIGQTVAKVTATDRDE---GENAKVTYELSVGDTSKFEVNPA-TGL 1154
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ T++PLDRE + Y + V A + G S + + +T+ I D NDN P F + Y +
Sbjct: 1155 VTTKRPLDREDQASYSLRVTA-MDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVT 1213
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDRE 856
EN+ G+ I + A+D D G N Y++ G F +D TG + +G +DRE
Sbjct: 1214 ENTANGSNILR---VLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVG-VVDRE 1269
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
Y L++ A+D+G S A + I + DENDN P F
Sbjct: 1270 ALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIF 1308
Score = 139 bits (337), Expect = 5e-31
Identities = 134/460 (29%), Positives = 210/460 (45%), Gaps = 36/460 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D NDN PVF S Y S++ N+ T + V A D D+G N ++ Y + ++
Sbjct: 1400 VVVNDVNDNPPVF-NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGND-- 1456
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV-VTIEVTRGTKG 565
FKIN +G + E + +E + ++ +Y+ VTI V
Sbjct: 1457 -EKRFKINSTSGVIMTTTPLDFEEKSQYGLEVT-----ATDSKYTAKTNVTIRVI----- 1505
Query: 566 NKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
N DI P F Y V N TSV ++ +D +SY ++ G ++ F++++
Sbjct: 1506 NLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGG-KDSDKFSIDQ 1564
Query: 625 RSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
RSG+I+ D L R +Y + V N LS +T T+ ++D ND ++S
Sbjct: 1565 RSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSS 1624
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQK 742
I ENSA ++ F +++ + N R I D I A G I +
Sbjct: 1625 SIL---ENSAPSS----FSFKLAATDADEGTNAR--ITYNLSRNDAFMIGASSGVITLAQ 1675
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + Y + + A + G A + + + D ND+ P+ ++ G + EN
Sbjct: 1676 PLDRENKSTYDLAIQAR-DHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPK 1734
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
T + I A+DAD G NA ++L E K +F +D TG + LDRE++ +Y
Sbjct: 1735 ETHVMR---ILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDIS-TKVPLDREQQAVY 1790
Query: 862 KLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEEN 899
L + D G LSS A++II + DE+DN P F E N
Sbjct: 1791 TLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYN 1830
Score = 136 bits (328), Expect = 6e-30
Identities = 138/471 (29%), Positives = 210/471 (44%), Gaps = 32/471 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T I +D + +FV + +T+ D NDN P F S +Y+ + + VG+++ ++ AVD D
Sbjct: 139 TMRISAFDGKHTTFVPL-ITVDDVNDNAPFFALS-VYKTGVYEDVAVGSIVRQLTAVDLD 196
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER 548
+G N + Y L TS F ++ + G + + E + + V Q S
Sbjct: 197 VGINARLSYSLVSGD----TSYFTVD-SQGVIRTKGAFDRETKASYQVALRAQDGG-SPS 250
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DV 606
R A V IE+ N+P F A Y V +V IG ++ + +D N D+
Sbjct: 251 RSGQATVEIEIL-DVNDNRPV---FSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADL 306
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVH 665
Y G F ++ +GV+TV L R Y +V + + L+ ++ ++
Sbjct: 307 RYSFTSGNTNHA-FTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLIN 365
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V D+ND V A+ VKEN+ Q+ T+ S + G + F I D
Sbjct: 366 VNDINDNPPVFSPSAYQS---RVKENTPAGT--QVSATDRDS---STNGALVFGIIKGND 417
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
G I K D E + Y +TV A ++GV QVTI+IED ND+ P
Sbjct: 418 DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQAR-DRGVPVKYDTAQVTIFIEDVNDHSP 476
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
VF + Y I E++ IG+ + + ATD D G Y L G K F++D N+G
Sbjct: 477 VFSPSNYSKQIPESTVIGSTVV---TVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSG 533
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEF 893
++ + LDRE Y L + ARD G SS + I + D NDN P F
Sbjct: 534 SIR-VSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIF 583
Score = 121 bits (292), Expect = 1e-25
Identities = 127/460 (27%), Positives = 196/460 (42%), Gaps = 32/460 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-L 499
S V+V + D NDN P F S LY ++ N G + V A D D G NG + Y L
Sbjct: 667 SLTVVKVMVDDVNDNPPQFAKS-LYTCTVGENLAAGVAVCYVTATDADSGANGKISYSIL 725
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
N+ T V + I ++L + A D S R+ +A T+ +
Sbjct: 726 SGNENMAFAMDRFTGEITTRVPLDRETI--ASYSLTINADD----GSLVRF-MAATTVNI 778
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
+ + + P F G P F + + GT VGQ+ D V+Y ++ G +G
Sbjct: 779 SIADENDNQ--PTFTG-PSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISG-NQG 834
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F ++ RSG+++V L R P Y A + SI + V V+DVND
Sbjct: 835 NSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRF 894
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K S ++E++ + + + G + ++ + +D+ I G
Sbjct: 895 EKSLFSG---EIREDA--SVHSTVLQVKVEDKDEGSNGAITLSLSGEG--SDNFTIDSTG 947
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ ++ PLD E Y++TV A + G S + QV I I + NDN P F I
Sbjct: 948 FVLSKTPLDYETTAAYQLTVTAR-DGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSI 1006
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E+ I T + + ATD+D GT F + G F +D+++G++ + LDRE
Sbjct: 1007 PEDVAINTHVVK---LNATDSD-GTPLTF-DIVEGNAGSSFKIDQSSGLIS-VAKRLDRE 1060
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
Y L + A +TG G S I + D NDN P FN
Sbjct: 1061 TTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFN 1100
Score = 119 bits (286), Expect = 7e-25
Identities = 121/465 (26%), Positives = 201/465 (43%), Gaps = 35/465 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+ M+ V +++ D NDN P F PS F++ ++ GT +G++ A D D+G NG V
Sbjct: 769 RFMAATTVNISIADENDNQPTFTGPS---RFNISEDSPTGTRVGQLTATDRDIGPNGAVT 825
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
Y + + + F+++P +G +SV + E + L V+ASD + S+ V
Sbjct: 826 YAIISGNQ---GNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHV 882
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
++V + P F + + + + + ++V Q++V D E ++ + L
Sbjct: 883 SVLDV-------NDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSG 935
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
E F ++ +G + L Y A + + S + +++VND
Sbjct: 936 EGSDNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNV 994
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ A + + E+ AI +++ +GT + F I +
Sbjct: 995 PSFVSPAQ---VTSIPED---VAI-NTHVVKLNATDSDGT-PLTFDIVEGNAGSSFKIDQ 1046
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY-QVTIYIEDENDNPPVFEHATY 792
G I K LDRE Y T++ + G +Y TI + D NDN PVF +Y
Sbjct: 1047 SSGLISVAKRLDRETTANY--TLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSY 1104
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ EN IG + + ATD DEG NA Y L F+V+ TG+V
Sbjct: 1105 AKSLHENLPIGQTVAK---VTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVT-TKRP 1160
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LDRE + Y L + A D G S+ A + + I D NDN P+F+Q
Sbjct: 1161 LDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQ 1205
Score = 113 bits (271), Expect = 5e-23
Identities = 121/460 (26%), Positives = 198/460 (43%), Gaps = 68/460 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALE--VKRYFVINER 997
IPE++ I T ++KLNA D D + L+ D +E F I++
Sbjct: 1006 IPEDVAINTHVVKLNATDSDG------------------TPLTFDIVEGNAGSSFKIDQS 1047
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFN 1053
G + VA+ L E+ + L + A + G+ +++ + + V DVND+ PVF Y +
Sbjct: 1048 SGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKS 1107
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ E + + KV ATD D G+NA +TY + DT FE++P TG+++ LDRE +
Sbjct: 1108 LHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTS-KFEVNPATGLVTTKRPLDREDQ 1166
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y L V A D+G D+NDNSP+F + K+ + N
Sbjct: 1167 ASYSLRVTAMDHG-KPSQSAVAAITLTINDLNDNSPQF------SQSKYTLTVTENTANG 1219
Query: 1174 ESVMMIPVYKATIEENAPIGTTV-----AKVFANDT-----DFIGNGNGLILYSLPQRKN 1223
+++ + N + ++ F D+ +G + L S +
Sbjct: 1220 SNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTIS 1279
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
++ G+P STA + +TVAD E + P+F S I+E V+ + + T+
Sbjct: 1280 AKDSGVPPWVSTAFVAITVAD-----ENDNSPIFASNETSYGIDEGVSIGSRVAVVTATD 1334
Query: 1284 HYENFKMR-YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
E + +Y + DT F I+ NG L + + +RE TY + +RA R
Sbjct: 1335 RDEGSNAQVFYSIVRGDTS---AFAINAMNGVLTVKKEINRETVPTYTLTIRAS----DR 1387
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
P M D ++ V + DVNDN P F +
Sbjct: 1388 GSP-------------MMTSDKELTVVVNDVNDNPPVFNS 1414
Score = 107 bits (257), Expect = 2e-21
Identities = 117/455 (25%), Positives = 189/455 (41%), Gaps = 55/455 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G+ I+++ A D D+G NG++ Y S + F I+ G
Sbjct: 1212 VTENTANGSNILRVLASDPDAGANGRVTYSIISGNH-------------GNAFRIDSTTG 1258
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V + E+ + L ISA D G V + V D ND+ P+F ++ ++
Sbjct: 1259 RITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGID 1318
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + V ATD D G NA + Y I DT F I+ + GVL+V E++RET
Sbjct: 1319 EGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTS-AFAINAMNGVLTVKKEINRETVPT 1377
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y LT+ A D G DVNDN P F + + + A S
Sbjct: 1378 YTLTIRASDRG-SPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQS------TS 1430
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNLGLPSL 1232
V+ + + + NA + ++ I + +G+I+ + P + K+Q L + +
Sbjct: 1431 VLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTAT 1490
Query: 1233 SS--TAILMVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK 1289
S TA VT+ + ++D P F + Y + EN +V ++ ++
Sbjct: 1491 DSKYTAKTNVTIR----VINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGS 1546
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIY 1349
+ Y I+ D+D F ID R+G + DRE+ Y + VR +
Sbjct: 1547 LSYSIVGGKDSD---KFSIDQRSGIISTADVLDRELVSLYAIQVR-------------VT 1590
Query: 1350 PVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
L +T V ++I D NDNSPKF + +
Sbjct: 1591 DAGNPPLSNLT----WVTIKILDENDNSPKFDSSS 1621
Score = 107 bits (256), Expect = 3e-21
Identities = 114/452 (25%), Positives = 192/452 (42%), Gaps = 55/452 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ IG+T++ + A DLDSG G++ Y S VK F I+ G
Sbjct: 487 IPESTVIGSTVVTVTATDLDSGPRGRLEYRLISG-------------NVKGAFNIDANSG 533
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFV--KDVNDHFPVFKKTWYNFNVE 1055
+ V+ L E+ + L + A DGG+ + + S RV + +D+ND+ P+F+ Y F V
Sbjct: 534 SIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGP-YVFRVS 592
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ +G+V ATDAD N ++ Y + +TD+ F I+ TG++++ +LD E + +
Sbjct: 593 ESSSPGHQIGQVAATDADDSSNGDVRYALS-DNTDV-FSINTSTGLITLKTQLDYEKKTQ 650
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y++TV A+D G DVNDN P+F + + L+ +
Sbjct: 651 YMVTVTAKDGG-TPSRSSLTVVKVMVDDVNDNPPQF----AKSLYTCTVGENLAAG--VA 703
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN-----QQNLGLP 1230
V + A N I ++ N + G I +P + +
Sbjct: 704 VCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINAD 763
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENF 1288
S + T ++ E ++P F I E+ + L T+ N
Sbjct: 764 DGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATDRDIGPNG 822
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
+ Y I++ N + +F +DPR+G L + + DRE +Y ++V+
Sbjct: 823 AVTYAIISGNQGN---SFQLDPRSGILSVRSTLDRETIPSYTLVVK-------------- 865
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
A D + V + DVNDN+P+F
Sbjct: 866 ---ASDAGSPQQSITASIHVSVLDVNDNAPRF 894
Score = 104 bits (249), Expect = 2e-20
Identities = 124/480 (25%), Positives = 202/480 (42%), Gaps = 67/480 (13%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I+VK +N A + +F I EN P I + A D DSG N I Y S
Sbjct: 57 VIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI-VTATDRDSGTNAAITYSLFSG---- 111
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFV 1035
+ F++N + G + L E++ + + ISA DG + + V
Sbjct: 112 -----------ENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKHTT--FVPLITV 158
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
DVND+ P F + Y V E ++ ++ A D D G NA L+Y + DT F +
Sbjct: 159 DDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY-FTV 217
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
GV+ G DRET+ Y + + A+D G DVNDN P F +
Sbjct: 218 DS-QGVIRTKGAFDRETKASYQVALRAQDGG-SPSRSGQATVEIEILDVNDNRPVFSS-- 273
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL 1215
++ ++++ +++ + NA + + N + G++
Sbjct: 274 --AQYTASVDEDVAIG--AAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVT 329
Query: 1216 YSLP---QRKNQQNLGL-------PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
S ++++ LGL P L+ T+ L++ V D+ D + PVF Y+
Sbjct: 330 VSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDIND-----NPPVFSPSAYQSR 384
Query: 1266 IEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
++EN A + VS + N + + I+ ND + F ID G + + +SPD E
Sbjct: 385 VKENTPAGTQ-VSATDRDSSTNGALVFGIIKGNDDGV---FTIDGSTGIISIAKSPDYEN 440
Query: 1326 KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD-VKVVVRIKDVNDNSPKFTNGN 1384
K Y++ V+A R +P KYD +V + I+DVND+SP F+ N
Sbjct: 441 KTRYDLTVQAR----DRGVP--------------VKYDTAQVTIFIEDVNDHSPVFSPSN 482
Score = 102 bits (244), Expect = 9e-20
Identities = 118/491 (24%), Positives = 211/491 (42%), Gaps = 67/491 (13%)
Query: 927 FALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
FAL V + G + E++ +G+ + +L A+DLD G+N ++ Y S +S D
Sbjct: 168 FALSVYKTG----VYEDVAVGSIVRQLTAVDLDVGINARLSY----------SLVSGDT- 212
Query: 987 EVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHF 1042
YF ++ + G + + E++ +++ + A DGG+ + +V + + DVND+
Sbjct: 213 ---SYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNR 268
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
PVF Y +V+E + V A+D D G NA+L Y +T+ F + +TGV+
Sbjct: 269 PVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVV 328
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEW 1160
+V+ LD E Y L + D G D+NDN P F A+ ++
Sbjct: 329 TVSRSLDFEQRSSYALGLSVTDRG-SPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKE 387
Query: 1161 KHPEADELSNHNFES----VMMIPVYKATIEENAPI-GTTVAKVFANDTDFIGNGNGLIL 1215
P ++S + +S ++ + K + I G+T A D+
Sbjct: 388 NTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDY----ENKTR 443
Query: 1216 YSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAP 1273
Y L + + G+P TA + + + DV D PVF Y +I E+ + +
Sbjct: 444 YDLTVQARDR--GVPVKYDTAQVTIFIEDVNDH-----SPVFSPSNYSKQIPESTVIGST 496
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
V V+ + ++ Y +++ N ++ F ID +G++ + DRE +Y + V
Sbjct: 497 VVTVTATDLDSGPRGRLEYRLISGN---VKGAFNIDANSGSIRVSSELDRETTPSYSLQV 553
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
A D +V + ++D+NDNSP F P V +
Sbjct: 554 E-----------------ARDGGSTSRSSSTRVTIALQDINDNSPIFQG---PYVFRVSE 593
Query: 1394 TAPFGYQVMQL 1404
++ G+Q+ Q+
Sbjct: 594 SSSPGHQIGQV 604
Score = 95.1 bits (226), Expect = 1e-17
Identities = 91/327 (27%), Positives = 154/327 (47%), Gaps = 24/327 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTV--DELTPTGEKAFIFLIAPIGPSLTIPLTVP 135
SA V + I +VNDNVP F+ +P VT +++ + G LT +
Sbjct: 978 SATAQVKITIINVNDNVPSFV-SPAQVTSIPEDVAINTHVVKLNATDSDGTPLTFDIVEG 1036
Query: 136 RGLTIFKDIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+ FK ++ K + +Y++V + ES + + +VLD +
Sbjct: 1037 NAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATI--RVLDVND 1094
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIH---AIDQDLGVGATLRYELISGNDRKLFSLDSV 249
F A K +H+ + + + A D+D G A + YEL G+ K F ++
Sbjct: 1095 NAPVFNPGSYA--KSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK-FEVNPA 1151
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G + ++ LD + + + + L+V A P ++A A + + + DLNDN P+F
Sbjct: 1152 TGLVTTKRPLDREDQAS-----YSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQS 1206
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQT 367
Y +++ EN NG ++L+V+A+D D G NG TY + + AF ID +G +TV
Sbjct: 1207 KYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVG-- 1264
Query: 368 VLDREAHSSLRMKVYAKETN-PSVVGT 393
V+DREA +S + + AK++ P V T
Sbjct: 1265 VVDREALASYNLTISAKDSGVPPWVST 1291
Score = 94.7 bits (225), Expect = 2e-17
Identities = 113/442 (25%), Positives = 186/442 (42%), Gaps = 51/442 (11%)
Query: 511 FKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F I+ +TG+++ E R+ L V A D AN + ++ V+ + K
Sbjct: 12 FTIDSSTGSITTTGRKFDRESESRYRLTVLAQDA-ANRCHKGRTVVVIDV------KDEN 64
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-----VSYDLLHGYEEGVPFAV 622
+ P+F Y F N+ T Q+ + A +++ ++Y L G + F +
Sbjct: 65 DNAPEFPLNSYVF----NIRENTPAAQVAIVTATDRDSGTNAAITYSLFSGENK---FMM 117
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
++G I V L + Y A + + + V TV DVND +
Sbjct: 118 NSKTGEIRTVTPLDHETKDSYTMRISAF-DGKHTTFVPLITVD--DVNDNAPFFALSVYK 174
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
++ ++ + G+ + Q+ ++ G N R + T + G I T+
Sbjct: 175 TGVY--EDVAVGSIVRQLTAVDLDV----GI-NARLSYSLVSGDTSYFTVDSQGVIRTKG 227
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
DRE + Y++ + A+ + G S +G V I I D NDN PVF A Y + E+ I
Sbjct: 228 AFDRETKASYQVALRAQ-DGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAI 286
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
G + + A+D D G NA Y+ G F +D TGVV + SLD E++ Y
Sbjct: 287 GAAMVT---VTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVT-VSRSLDFEQRSSY 342
Query: 862 KLSLVARDTGG--LSSEAELIIMIGDENDNKPEF------NQIEENSKV-----RIHRET 908
L L D G L+ + L+I + D NDN P F ++++EN+ R++
Sbjct: 343 ALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVSATDRDS 402
Query: 909 KLNGTAGFTIIEVKPKNKFALD 930
NG F II+ F +D
Sbjct: 403 STNGALVFGIIKGNDDGVFTID 424
Score = 93.1 bits (221), Expect = 5e-17
Identities = 94/351 (26%), Positives = 144/351 (41%), Gaps = 20/351 (5%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S +V + I DVNDN P+F Y +VDE G A + + +
Sbjct: 252 SGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIG--AAMVTVTASDKDNGNNADLRYS 309
Query: 138 LTIFKDIRAFDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY--DA 192
T AF D T + + + S G + P+ +L D
Sbjct: 310 FTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDI 369
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
D A R+ + + A D+D L + +I GND +F++D G
Sbjct: 370 NDNPPVFSPSAYQSRVKENTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGI 429
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ + K D + + + L VQA P+K A+V I + D+ND+ P F Y+
Sbjct: 430 ISIAKSPDYENK-----TRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYS 484
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLD 370
I E+ G +V+ V ATD D G G Y+L + KGAF+ID SG ++R + LD
Sbjct: 485 KQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSG--SIRVSSELD 542
Query: 371 REAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
RE S ++V A++ T S Q + N+P+ + YVF
Sbjct: 543 RETTPSYSLQVEARDGG----STSRSSSTRVTIALQDINDNSPIFQGPYVF 589
Score = 91.9 bits (218), Expect = 1e-16
Identities = 58/168 (34%), Positives = 88/168 (52%), Gaps = 8/168 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G L Y LISGN + F++D+ +GS+ + ELD + ++ LQV+
Sbjct: 500 VTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRET-----TPSYSLQVE 554
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + +++ RV I L D+NDN P F+ Y + E+ G + QV ATD D
Sbjct: 555 ARDGGSTSRSSSTRVTIALQDINDNSPIFQGP-YVFRVSESSSPGHQIGQVAATDADDSS 613
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG+ Y L D FSI+ +G +T++ Q LD E + + V AK+
Sbjct: 614 NGDVRYALSDNTDVFSINTSTGLITLKTQ--LDYEKKTQYMVTVTAKD 659
Score = 91.5 bits (217), Expect = 2e-16
Identities = 79/312 (25%), Positives = 141/312 (45%), Gaps = 18/312 (5%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-APIGPSLTIPLTVPRGLTIF 141
V + ++D NDN P F Y + E TP + A + G + I ++ G F
Sbjct: 56 VVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRDSGTNAAITYSLFSGENKF 115
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVI 201
+ TP + + A + H + L V D + F L +
Sbjct: 116 MMNSKTGEIRTVTP---LDHETKDSYTMRISAFDGKHTTFVPLITVDDVNDNAPFFALSV 172
Query: 202 MASGKRIHKEILFPEPIH---AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKE 258
+G +++++ + A+D D+G+ A L Y L+SG D F++DS G + +
Sbjct: 173 YKTG--VYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSG-DTSYFTVDS-QGVIRTKGA 228
Query: 259 LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN 318
D + + + Q + ++A +P ++ QA VEIE+LD+NDN P F Y S+ E+
Sbjct: 229 FDRETKASYQ-----VALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDED 283
Query: 319 LPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
+ G +++ V A+DKD G N + Y + AF++D +G +TV ++ + +
Sbjct: 284 VAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYA 343
Query: 377 LRMKVYAKETNP 388
L + V + + P
Sbjct: 344 LGLSVTDRGSPP 355
Score = 91.5 bits (217), Expect = 2e-16
Identities = 87/321 (27%), Positives = 144/321 (44%), Gaps = 26/321 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVP 135
+A++++TV D NDN PIF +DE G + + G + + ++
Sbjct: 1291 TAFVAITV--ADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV 1348
Query: 136 RGLTIFKDIRAFD-----RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
RG T I A + + + N + + +D G + S + +++ V D
Sbjct: 1349 RGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDN 1408
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+ S + + + A D D+G A LRY +ISGND K F ++S +
Sbjct: 1409 PPVFNSQSYI--GSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTS 1466
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + LD + + + + L+V A+ TA+ V I +++LND P F
Sbjct: 1467 GVIMTTTPLDFE-----EKSQYGLEVTATDSKY---TAKTNVTIRVINLNDITPAFTQQN 1518
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTV 368
Y S+ EN P SV++V A+D+D G +Y + K + FSID RSG ++ + V
Sbjct: 1519 YTASVRENSPTSTSVVKVSASDRD--SFGSLSYSIVGGKDSDKFSIDQRSGIISTAD--V 1574
Query: 369 LDREAHSSLRMKVYAKET-NP 388
LDRE S ++V + NP
Sbjct: 1575 LDRELVSLYAIQVRVTDAGNP 1595
Score = 87.0 bits (206), Expect = 3e-15
Identities = 87/321 (27%), Positives = 148/321 (46%), Gaps = 38/321 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGLT- 139
VT++IEDVND+ P+F + Y + E T G + GP + + G
Sbjct: 464 VTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVK 523
Query: 140 -IFK------DIR-AFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDY 190
F IR + + D+ TP+ YS+ V D G + SS + + L+ + D
Sbjct: 524 GAFNIDANSGSIRVSSELDRETTPS----YSLQVEARDGGSTSRSSSTRVTIALQDINDN 579
Query: 191 DA---GDKEFQLVIMAS-GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
G F++ +S G +I + + A D D +RY L D +FS+
Sbjct: 580 SPIFQGPYVFRVSESSSPGHQIGQ-------VAATDADDSSNGDVRYALSDNTD--VFSI 630
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
++ G + L+ +LD + + +++ V A P +++ V++ + D+NDN P+F
Sbjct: 631 NTSTGLITLKTQLDYEKK-----TQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQF 685
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVR 364
Y ++ ENL G +V V ATD D G NG+ +Y + + AF++D +G +T R
Sbjct: 686 AKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTR 745
Query: 365 NQTVLDREAHSSLRMKVYAKE 385
LDRE +S + + A +
Sbjct: 746 --VPLDRETIASYSLTINADD 764
Score = 87.0 bits (206), Expect = 3e-15
Identities = 55/167 (32%), Positives = 89/167 (53%), Gaps = 9/167 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D+G + Y +ISGN F LD +G L + LD + ++ L V+AS
Sbjct: 813 ATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGILSVRSTLDRET-----IPSYTLVVKAS 867
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ A + + +LD+NDN P FE ++ I E+ +VLQV DKD+G NG
Sbjct: 868 DAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNG 927
Query: 340 EFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
T L + F+ID +G+ V ++T LD E ++ ++ V A++
Sbjct: 928 AITLSLSGEGSDNFTID-STGF--VLSKTPLDYETTAAYQLTVTARD 971
Score = 83.4 bits (197), Expect = 4e-14
Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 21/222 (9%)
Query: 935 GP-LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
GP +F + E+ G I ++ A D D NG +RY + + F
Sbjct: 585 GPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDV---------------FS 629
Query: 994 INERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTW 1049
IN G + + L E +++ + ++A DGG + + V+V V DVND+ P F K+
Sbjct: 630 INTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSL 689
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y V E + V ATDAD G N ++Y I + ++ F + TG ++ LD
Sbjct: 690 YTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLD 749
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
RET Y LT+ A D+G D NDN P F
Sbjct: 750 RETIASYSLTINA-DDGSLVRFMAATTVNISIADENDNQPTF 790
Score = 83.0 bits (196), Expect = 6e-14
Identities = 166/657 (25%), Positives = 254/657 (38%), Gaps = 103/657 (15%)
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
+DN VF T G I +++ E K ++ T D GT + T+ K M D D
Sbjct: 622 SDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVV---KVMVD-D 677
Query: 841 ENTGVVKF--------IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDN--K 890
N +F +G++L + Y + A G + + I+ G+EN
Sbjct: 678 VNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDA--DSGANGKISYSILSGNENMAFAM 735
Query: 891 PEFNQIEENSKVRIHRET------KLNGTAGFTI--IEVKPKNKFALDVDQLGPLFLIP- 941
F E ++V + RET +N G + + N D + P F P
Sbjct: 736 DRFTG-EITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPS 794
Query: 942 -----ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
E+ P GT + +L A D D G NG + Y S F ++
Sbjct: 795 RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISG-------------NQGNSFQLDP 841
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNF 1052
R G + V +L E+ + L + A D G+ +I S+ V V DVND+ P F+K+ ++
Sbjct: 842 RSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSG 901
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E + +V D D G N +T + +D F I TG + LD ET
Sbjct: 902 EIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSD-NFTIDS-TGFVLSKTPLDYET 959
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
Y LTV ARD G +VNDN P F + ++ PE ++ H
Sbjct: 960 TAAYQLTVTARDGG-SPSKSATAQVKITIINVNDNVPSFVSPAQVT--SIPEDVAINTH- 1015
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL------------YSLPQ 1220
+ AT + P+ + + A + I +GLI Y+L
Sbjct: 1016 ------VVKLNATDSDGTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVV 1069
Query: 1221 RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVS 1278
R + S+ + A + V DV D + PVF Y + EN + V V+
Sbjct: 1070 RATETGSQGESVYNNA--TIRVLDVND-----NAPVFNPGSYAKSLHENLPIGQTVAKVT 1122
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ EN K+ Y L+ DT F ++P G + R DRE + +Y + V A
Sbjct: 1123 ATDRDEGENAKVTYE-LSVGDTS---KFEVNPATGLVTTKRPLDREDQASYSLRVTA--- 1175
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTA 1395
+ H P V + + I D+NDNSP+F+ L T TA
Sbjct: 1176 -----MDHG-KPSQSAV--------AAITLTINDLNDNSPQFSQSKYTL-TVTENTA 1217
Score = 81.8 bits (193), Expect = 1e-13
Identities = 91/375 (24%), Positives = 157/375 (41%), Gaps = 26/375 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + + NV + +++ ND P F N Y S++ N+ T + KV A D D G +
Sbjct: 1491 DSKYTAKTNVTIRVINLNDITPAFTQQN-YTASVRENSPTSTSVVKVSASDRD--SFGSL 1547
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLA 553
Y + + + F I+ +G +S A+ L +A+ V +D P +L
Sbjct: 1548 SYSIVGGKD---SDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLS---NLT 1601
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
VTI++ + P F + Y + N + ++ DA E + + +
Sbjct: 1602 WVTIKIL----DENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNAR--ITYN 1655
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDVND 671
F + SGVIT+ L R N+ YD A+ +++ ++ T+ V +D+ND
Sbjct: 1656 LSRNDAFMIGASSGVITLAQPLDRENKSTYDL-AIQARDHGTPPQASSITIRVTVIDIND 1714
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
R ++ S + V+EN + S + F + + + +
Sbjct: 1715 HRPLINS---SSLRGSVRENQPKET--HVMRILASDADTGLNAELTFSLLSNEHKSVFTL 1769
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I T+ PLDRE++ VY + I +KG S + + V I + DE+DN P F+
Sbjct: 1770 DNTTGDISTKVPLDREQQAVYTLR-IGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTE 1828
Query: 792 YEGFIMENSKIGTEI 806
Y I E+ G I
Sbjct: 1829 YNVTISESLPRGASI 1843
Score = 79.8 bits (188), Expect = 5e-13
Identities = 52/157 (33%), Positives = 82/157 (52%), Gaps = 10/157 (6%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+L Y ++ G D FS+D +G + LD + + + +QV+ + NP +
Sbjct: 1546 SLSYSIVGGKDSDKFSIDQRSGIISTADVLDREL-----VSLYAIQVRVTDAGNPPLSNL 1600
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
V I++LD NDN P+F+ Y+ SI+EN P+ FS ++ ATD D+G N TY L
Sbjct: 1601 TWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFS-FKLAATDADEGTNARITYNL-SR 1658
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
AF I SG +T+ LDRE S+ + + A++
Sbjct: 1659 NDAFMIGASSGVITLAQP--LDRENKSTYDLAIQARD 1693
Score = 77.8 bits (183), Expect = 2e-12
Identities = 50/152 (32%), Positives = 78/152 (51%), Gaps = 9/152 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLE-KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
Y ++ GND+ +F++DS GS+ ++ D ++E + + L V A N +
Sbjct: 1 YSIMDGNDQGMFTIDSSTGSITTTGRKFDRESE-----SRYRLTVLAQDAANRCHKGRTV 55
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V I++ D NDN PEF ++ Y +I EN P V V ATD+D G N TY L +
Sbjct: 56 VVIDVKDENDNAPEFPLNSYVFNIRENTP-AAQVAIVTATDRDSGTNAAITYSLFSGENK 114
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
F ++ ++G +R T LD E S M++ A
Sbjct: 115 FMMNSKTG--EIRTVTPLDHETKDSYTMRISA 144
Score = 77.0 bits (181), Expect = 4e-12
Identities = 94/354 (26%), Positives = 145/354 (40%), Gaps = 44/354 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P T+++K++A D DS F S Y +D F I++R G
Sbjct: 1523 VRENSPTSTSVVKVSASDRDS---------FGSLSYSIVGGKDSDK------FSIDQRSG 1567
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A L E S + + + D GN L++ V + + D ND+ P F + Y+ ++
Sbjct: 1568 IISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSIL 1627
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E K+ ATDAD G NA +TY + +D F I +GV+++ LDRE +
Sbjct: 1628 ENSAPSSFSFKLAATDADEGTNARITYNLSRNDA---FMIGASSGVITLAQPLDRENKST 1684
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y L + ARD+G D+ND+ P + L E H
Sbjct: 1685 YDLAIQARDHG-TPPQASSITIRVTVIDINDHRPLINS--SSLRGSVRENQPKETH---- 1737
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ---------- 1225
VM I A NA + ++ + N G I +P + QQ
Sbjct: 1738 VMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVA 1797
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+ G PSLSS A +++ V D D P F Y + I E++ +V +
Sbjct: 1798 DKGNPSLSSVADVIIDVIDEDDNC-----PRFQPTEYNVTISESLPRGASIVQV 1846
Score = 76.6 bits (180), Expect = 5e-12
Identities = 87/329 (26%), Positives = 134/329 (40%), Gaps = 28/329 (8%)
Query: 1010 ESEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
ES +RL + A D N V + VKD ND+ P F Y FN+ E +V V
Sbjct: 33 ESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQV-AIV 91
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
ATD D G NA +TY + + F ++ TG + LD ET+D Y + + A D
Sbjct: 92 TATDRDSGTNAAITYSLFSGEN--KFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG-- 147
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS-NHNFESVMMIPVYKATI 1186
DVNDN+P F+A + + S +V + A +
Sbjct: 148 ---KHTTFVPLITVDDVNDNAP-FFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARL 203
Query: 1187 EENAPIGTTVAKVFANDTDFIGNGNGLI----LYSLPQRKNQQNLGLPSLSSTAILMVTV 1242
+ G T F D+ + G S Q+ G PS S A + + +
Sbjct: 204 SYSLVSGDT--SYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEI 261
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYILNENDT 1300
DV D ++PVF S Y ++E+V +V++ + ++ N +RY + N
Sbjct: 262 LDVND-----NRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGN-- 314
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
F +D G + + RS D E + +Y
Sbjct: 315 -TNHAFTLDAVTGVVTVSRSLDFEQRSSY 342
Score = 75.8 bits (178), Expect = 9e-12
Identities = 81/324 (25%), Positives = 136/324 (41%), Gaps = 33/324 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFL----------DTPYHVTVDELTPT----GEKAFIFLIAP 123
S Y + T+ + DVNDN P+F + P TV ++T T GE A +
Sbjct: 1080 SVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELS 1139
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVL 182
+G + + GL K R DR+ YS+ V+ D G + + L
Sbjct: 1140 VGDTSKFEVNPATGLVTTK--RPLDRE------DQASYSLRVTAMDHGKPSQSAVAAITL 1191
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
+ + D + + + + + + + A D D G + Y +ISGN
Sbjct: 1192 TINDLNDNSPQFSQSKYTLTVTENTANGSNILR--VLASDPDAGANGRVTYSIISGNHGN 1249
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F +DS G + + +D +A ++ L + A P + A V I + D NDN
Sbjct: 1250 AFRIDSTTGRITVVGVVDREA-----LASYNLTISAKDSGVPPWVSTAFVAITVADENDN 1304
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWL 361
P F + + I E + G V V ATD+D+G N + Y + AF+I+ +G L
Sbjct: 1305 SPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVL 1364
Query: 362 TVRNQTVLDREAHSSLRMKVYAKE 385
TV+ + ++RE + + + A +
Sbjct: 1365 TVKKE--INRETVPTYTLTIRASD 1386
Score = 74.9 bits (176), Expect = 2e-11
Identities = 40/117 (34%), Positives = 66/117 (56%), Gaps = 5/117 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G+ A L + L+S + +F+LD+ G + + LD + Q + L++
Sbjct: 1741 ILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDRE-----QQAVYTLRIG 1795
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ NP ++ A V I+++D +DN P F+ YN++I E+LP G S++QV A D D
Sbjct: 1796 VADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852
Score = 74.5 bits (175), Expect = 2e-11
Identities = 82/354 (23%), Positives = 155/354 (43%), Gaps = 22/354 (6%)
Query: 47 DSPQNVVKFRLGCDFDEGDDL-VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVT 105
+S V+ DF+E + + A ++ +A +VT+ + ++ND P F Y +
Sbjct: 1463 NSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINLNDITPAFTQQNYTAS 1522
Query: 106 VDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDV-HYSIV 164
V E +PT + ++ ++ G D + D+ +DV +V
Sbjct: 1523 VRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKD--SDKFSIDQRSGIISTADVLDRELV 1580
Query: 165 SGNDDGHFALESSHKPVLLLR----KVLDYDAGDKEFQLVIMASGKRIHKE-ILFPEPIH 219
S ++ + P+ L K+LD + +F +S + F +
Sbjct: 1581 SLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLA 1640
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G A + Y L S ND F + + +G + L + LD + + +T+ L +QA
Sbjct: 1641 ATDADEGTNARITYNL-SRNDA--FMIGASSGVITLAQPLDRENK-----STYDLAIQAR 1692
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + + + + ++D+ND+ P S+ EN P V++++A+D D G N
Sbjct: 1693 DHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNA 1752
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV-YAKETNPSV 390
E T+ L ++ K F++D +G + + LDRE + +++ A + NPS+
Sbjct: 1753 ELTFSLLSNEHKSVFTLDNTTG--DISTKVPLDREQQAVYTLRIGVADKGNPSL 1804
Score = 67.3 bits (157), Expect = 3e-09
Identities = 84/324 (25%), Positives = 140/324 (43%), Gaps = 27/324 (8%)
Query: 74 LNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIP 131
L + A +V + I D NDN P F P + E +PTG + IGP+ +
Sbjct: 767 LVRFMAATTVNISIADENDNQPTFTG-PSRFNISEDSPTGTRVGQLTATDRDIGPNGAVT 825
Query: 132 LTV---PRGLTIFKDIRAFDRDKPNTPNSDV--HYSIVSGNDDGHFALESSHKPVLLLRK 186
+ +G + D R+ +T + + Y++V D +S + +
Sbjct: 826 YAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHV--S 883
Query: 187 VLDYDAGDKEFQLVIMASGKR----IHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
VLD + F+ + + R +H +L + D+D G + L SG
Sbjct: 884 VLDVNDNAPRFEKSLFSGEIREDASVHSTVL---QVKVEDKDEGSNGAITLSL-SGEGSD 939
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F++DS F+ + LD E + L V A +P K+A A+V+I ++++NDN
Sbjct: 940 NFTIDSTG---FVLSKTPLDYETTA---AYQLTVTARDGGSPSKSATAQVKITIINVNDN 993
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
+P F SI E++ V+++ ATD D G F + +F ID SG ++
Sbjct: 994 VPSFVSPAQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAGSSFKIDQSSGLIS 1052
Query: 363 VRNQTVLDREAHSSLRMKVYAKET 386
V + LDRE ++ + V A ET
Sbjct: 1053 VAKR--LDRETTANYTLVVRATET 1074
Score = 50.8 bits (116), Expect = 3e-04
Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DEND 888
G + MF +D +TG + G DRE + Y+L+++A+D + +++I DEND
Sbjct: 6 GNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDEND 65
Query: 889 NKPEF 893
N PEF
Sbjct: 66 NAPEF 70
Score = 42.3 bits (95), Expect = 0.099
Identities = 64/268 (23%), Positives = 107/268 (39%), Gaps = 37/268 (13%)
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNG-ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y I + F I TG ++ G + DRE+E +Y LTV+A+D
Sbjct: 1 YSIMDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQD-AANRCHKGRTVVVID 59
Query: 1141 XXDVNDNSPKF----YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV 1196
D NDN+P+F Y F+ + P A + + AT ++
Sbjct: 60 VKDENDNAPEFPLNSYVFN--IRENTPAA------------QVAIVTATDRDSGTNAAIT 105
Query: 1197 AKVFANDTDFIGNG-NGLILYSLP---QRKNQQNLGLPSLS---STAILMVTVADVPDEV 1249
+F+ + F+ N G I P + K+ + + + +T + ++TV DV D
Sbjct: 106 YSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKHTTFVPLITVDDVND-- 163
Query: 1250 EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNENDTDIRRTFVI 1308
+ P F Y+ + E+V + L + R Y L DT F +
Sbjct: 164 ---NAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY---FTV 217
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
D + G + + DRE K +Y+V +RA+
Sbjct: 218 DSQ-GVIRTKGAFDRETKASYQVALRAQ 244
Score = 41.1 bits (92), Expect = 0.23
Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 17/138 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P T ++++ A D D+GLN ++ + S E K F ++ G
Sbjct: 1728 VRENQPKETHVMRILASDADTGLNAELTFSLLSN-------------EHKSVFTLDNTTG 1774
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L E + + L I D GN L+ V + V D +D+ P F+ T YN +
Sbjct: 1775 DISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTIS 1834
Query: 1056 EAQYTRRVLGKVDATDAD 1073
E+ + +V A D D
Sbjct: 1835 ESLPRGASIVQVTARDID 1852
Score = 40.3 bits (90), Expect = 0.40
Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 31/179 (17%)
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGN-------GNGLILYSLPQRK---NQQNLGLPS 1231
Y A++ EN+P T+V KV A+D D G+ G +S+ QR + ++
Sbjct: 1519 YTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRE 1578
Query: 1232 LSSTAILMVTVADVPDEV-------------EMSDKPVFISRYYELEIEENVNAPVEL-V 1277
L S + V V D + E + P F S Y I EN +AP
Sbjct: 1579 LVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILEN-SAPSSFSF 1637
Query: 1278 SLNLTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
L T+ E R Y L+ ND F+I +G + L + DRE K TY++ ++A
Sbjct: 1638 KLAATDADEGTNARITYNLSRNDA-----FMIGASSGVITLAQPLDRENKSTYDLAIQA 1691
>UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homolog
precursor; n=49; Euteleostomi|Rep: Cadherin-related tumor
suppressor homolog precursor - Homo sapiens (Human)
Length = 4590
Score = 157 bits (382), Expect = 2e-36
Identities = 150/499 (30%), Positives = 229/499 (45%), Gaps = 46/499 (9%)
Query: 429 TENIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV 485
T NI YD Q ++ + V ++DANDN P F+ + Y + + +V + I +V+A
Sbjct: 789 TLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQES-YFVEVSEDKEVHSEIIQVEAT 847
Query: 486 DPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQP 542
D DLG NG V Y + LT T F I+ TG V++A P+ L+ H+L +EA DQ
Sbjct: 848 DKDLGPNGHVTYSI-----LTDTDTFSIDSVTGVVNIAR-PLDRELQHEHSLKIEARDQA 901
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF- 601
E + V ++V+ + P P F+ Y V ++ GT + + +D
Sbjct: 902 R---EEPQLFSTVVVKVSLEDVNDNP--PTFIPPNYRVKVREDLPEGTVIMWLEAHDPDL 956
Query: 602 -EQNDVSYDLL-HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLS 657
+ V Y LL HG EG F V++ SG + +V L + +Y+ A + +LS
Sbjct: 957 GQSGQVRYSLLDHG--EG-NFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLS 1013
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA---GAAIGQIFHTNMSSIYGNGT- 713
V VVDVN+ H P+ E A +G + T + G
Sbjct: 1014 STCYVEVEVVDVNEN-------LHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRD 1066
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
G +R+ I + V E G I T LDRE Y +TV A ++GV+ + ++
Sbjct: 1067 GEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFAT-DQGVVPLSSFIEI 1125
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GE 832
I +ED NDN P Y IMENS + I+A D D +N MY + G
Sbjct: 1126 YIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQ---IEAFDPDSSSNDKLMYKITSGN 1182
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNK 890
+ F + TG++ LDRE++ + L + D G S+ A +I+ I DENDNK
Sbjct: 1183 PQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNK 1242
Query: 891 PEFNQIEENSKVRIHRETK 909
P+F +++ K+R+ K
Sbjct: 1243 PQF--LQKFYKIRLPEREK 1259
Score = 140 bits (340), Expect = 2e-31
Identities = 137/467 (29%), Positives = 210/467 (44%), Gaps = 38/467 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++F V V L D NDN P F + YE ++ S+A GT + K A D D G N + Y +
Sbjct: 2580 VAFCTVNVILTDDNDNAPQFRATK-YEVNIGSSAAKGTSVVK-SASDADEGSNADITYAI 2637
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI-LEGRH-ALFVEASDQPANPSERRYSLAVVTI 557
+ S ++ +IN +G ++ ES I LE FV A D N S + S+ +V +
Sbjct: 2638 EADSE-SVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVD---NGSPSKESVVLVYV 2693
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY--- 614
++ + +P F Y F V +V +GT + IR A V Y L+ G
Sbjct: 2694 KILPP----EMQLPKFSEPFYTFTVSEDVPVGTEIDLIR---AEHSGTVLYSLVKGNTPE 2746
Query: 615 -EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLSIVTNATVHVVDVND 671
F ++ +SG + + L Y F +A Q++ + + ++ V D ND
Sbjct: 2747 SNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDAND 2806
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ--DVTDD 729
V SP + EN G + ++ S G V + + Q +V +
Sbjct: 2807 NSPVF---ESSPYEAFIVENLPGGS--RVIQIRASDADSGTNGQVMYSLDQSQSVEVIES 2861
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
AI E G I T K LD EKRD Y++ V+A + I + V + + D ND+PP F
Sbjct: 2862 FAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFT 2921
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGE---GKEMFDVDENTG 844
Y+G + E+ G I I+ TDAD E N Y + G G+ + +N
Sbjct: 2922 AEIYKGTVSEDDPQGGVIA---ILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEW 2978
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
V ++ LDREK+ Y L++ A D G SS+A + + + D NDN P
Sbjct: 2979 KV-YVKKPLDREKRDNYLLTITATD-GTFSSKAIVEVKVLDANDNSP 3023
Score = 125 bits (301), Expect = 1e-26
Identities = 199/848 (23%), Positives = 350/848 (41%), Gaps = 93/848 (10%)
Query: 106 VDELTPTGEKAFIFLIAPIGPSLTIP-LTVP-RGLTIFKDIRA-FDRDKPNTPNSD-VHY 161
VD +P+ E + + + P + +P + P T+ +D+ + D +S V Y
Sbjct: 2678 VDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEIDLIRAEHSGTVLY 2737
Query: 162 SIVSGND-----DGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE 216
S+V GN D F ++ L L K LD++ K +Q I+A + E+
Sbjct: 2738 SLVKGNTPESNRDESFVIDRQSGR-LKLEKSLDHET-TKWYQFSILARCTQDDHEM---- 2791
Query: 217 PIHAIDQDLGV-GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ ++D + V A + + + F ++++ G + + DA+ +
Sbjct: 2792 -VASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQV-MYS 2849
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV-----ENLP-NGFSVLQVM 329
+ SQ +++ +E + L + D Y I +V E + + +++ V
Sbjct: 2850 LDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVT 2909
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSID-PRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
TD + FT ++ KG S D P+ G + + + T D E + +V T
Sbjct: 2910 VTDVNDSPP-RFTAEIY--KGTVSEDDPQGGVIAILSTTDADSE---EINRQVTYFITGG 2963
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
+G FA +W+ + PL++ +K I D S VEV
Sbjct: 2964 DPLGQFAVETIQNEWK---VYVKKPLDR------EKRDNYLLTITATDGTFSSKAIVEVK 3014
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
+LDANDN+PV LY ++ + G +I ++ A D D+ N + Y L +
Sbjct: 3015 VLDANDNSPV-CEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSG----A 3069
Query: 509 SPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
FK+NP+TG + + +P+ A L V A+D + + VVT+E
Sbjct: 3070 EKFKLNPDTGELKTS-TPLDREEQAVYHLLVRATDGGGRFCQ---ASIVVTLEDV----- 3120
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVE 623
+ P+F PY V N GT + +++ DA + Y L+ + F++
Sbjct: 3121 -NDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADG--QFSIN 3177
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDERGVLLKGAH 681
E SG+I + L R + +Y A+ + + T V V+D+ND
Sbjct: 3178 ELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDIND---------- 3227
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYG-----NGTGNVRFLIANQQDVTDDIAIAEDG 736
+P +F +E A + + T + +Y + + I + + ++ G
Sbjct: 3228 NPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTG 3287
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+F + LD E Y +TV A + G S + + V + + D NDN PVF TY I
Sbjct: 3288 AVFIIENLDYESSHEYYLTVEAT-DGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVI 3346
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDR 855
E++ + + + A DAD +N+ Y++ G F +D G VK + LDR
Sbjct: 3347 SEDAVLEQSV---ITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVK-VTKLLDR 3402
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
E Y L++ A D G + + I + D NDN P F++ N V I N
Sbjct: 3403 ETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSR--GNYSVIIQE----NKP 3456
Query: 914 AGFTIIEV 921
GF+++++
Sbjct: 3457 VGFSVLQL 3464
Score = 124 bits (299), Expect = 2e-26
Identities = 136/476 (28%), Positives = 213/476 (44%), Gaps = 35/476 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+ D S V VT++ N ++P F+ N YE + NA + T++ +VK D D G
Sbjct: 2467 NLSVSDGVFRSSTQVHVTVIGGNLHSPAFL-QNEYEVELAENAPLHTLVMEVKTTDGDSG 2525
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
G V Y + N F IN G + E E A V + A + +
Sbjct: 2526 IYGHVTYHIV---NDFAKDRFYINER-GQIFTLEKLDRE-TPAEKVISVRLMAKDAGGKV 2580
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSY 608
+ V + +T + + P F YE +GS+ GTSV + +DA E + D++Y
Sbjct: 2581 AFCTVNVILT----DDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SASDADEGSNADITY 2635
Query: 609 DLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+ E V + + SGVIT + L + F A+ +N + S + V+V
Sbjct: 2636 -AIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAV-DNGSPSKESVVLVYV 2693
Query: 667 VDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSI-YGNGTGNVRFLIANQQ 724
+ E L K + F V E+ G I I + ++ Y GN ++
Sbjct: 2694 KILPPEMQ-LPKFSEPFYTFTVSEDVPVGTEIDLIRAEHSGTVLYSLVKGNTPESNRDES 2752
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
V D + G + +K LD E Y+ +++A + V+I ++D NDN
Sbjct: 2753 FVID----RQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNS 2808
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKEMFDVD 840
PVFE + YE FI+EN G+ + I+A+DAD GTN MY+L E E F ++
Sbjct: 2809 PVFESSPYEAFIVENLPGGSRVIQ---IRASDADSGTNGQVMYSLDQSQSVEVIESFAIN 2865
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEF 893
TG + + + LD EK+ Y++ +VA D G LSS A + + + D ND+ P F
Sbjct: 2866 METGWITTLKE-LDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRF 2920
Score = 122 bits (294), Expect = 8e-26
Identities = 166/700 (23%), Positives = 293/700 (41%), Gaps = 65/700 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D G + Y + + N F++D G++ + LD + L + L+++
Sbjct: 485 LSAVDPDEGENGYVTYSIANLNHVP-FAIDHFTGAVSTSENLD----YELMPRVYTLRIR 539
Query: 278 ASQLNNPLKT-AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS P + + I L +LNDN P FE +I +L G + V A D D+
Sbjct: 540 ASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADEL 599
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
+ ++ + + FS++P SG L+++ SL + AK + S+ T D
Sbjct: 600 QLVQYQIEAGNELDLFSLNPNSGVLSLKR----------SLMDGLGAKVSFHSLRITATD 649
Query: 397 SQRIAKWRRQPLETN---APLEKTTYVFPDKVGTKTENIE--YYDEQLMSFVNVEVTLLD 451
+ A PL N A K + ++ G E +L + VE D
Sbjct: 650 GENFAT----PLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFD 705
Query: 452 ANDNN---PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
++ N P F + +K N VG+ + + + D D G NG ++Y S
Sbjct: 706 SHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVY---AVSGGNED 762
Query: 509 SPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
S F I+ TG + + SP+ ++ L + D L VV ++
Sbjct: 763 SCFMIDMETGMLKIL-SPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDA-----N 816
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVE 623
+ P P+F+ Y V + + + + Q+ D V+Y +L + F+++
Sbjct: 817 DNP--PEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSILTDTD---TFSID 871
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+GV+ + L R + + + A +E L V + DVND +
Sbjct: 872 SVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPN 931
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ V+E+ + + + +G VR+ + + + D+ G +
Sbjct: 932 YR---VKVREDLPEGTVIMWLEAHDPDL--GQSGQVRYSLLDHGEGNFDVD-KLSGAVRI 985
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHATYEGFIME 798
+ LD EK+ VY +TV A+ +S + V + + D N+N PPVF +G + E
Sbjct: 986 VQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKE 1045
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREK 857
++ +G+ + + A D D G + Y++ G G +F + E TGV++ D LDRE
Sbjct: 1046 DAPVGSLVM---TVSAHDEDAGRDGEIRYSIRDGSGVGVFKIGEETGVIE-TSDRLDRES 1101
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
Y L++ A D G LSS E+ I + D NDN P+ ++
Sbjct: 1102 TSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSE 1141
Score = 120 bits (288), Expect = 4e-25
Identities = 120/463 (25%), Positives = 204/463 (44%), Gaps = 32/463 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ VTL D NDN P F ++ Y ++ N + GT++ +V+A D D G N +LY L ++
Sbjct: 3112 SIVVTLEDVNDNAPEF-SADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSA 3170
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F IN +G + + E P+ L+ + L ++A DQ RR + A T+ V+
Sbjct: 3171 D----GQFSINELSGIIQL-EKPLDRELQAVYTLSLKAVDQGL---PRRLT-ATGTVIVS 3221
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGV 618
+ P P F Y V ++ +GT V Q+ D +++Y ++ G E G
Sbjct: 3222 VLDINDNP--PVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHG- 3278
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
F+++ ++G + ++++L + Y A +LS V V+V D+ND V
Sbjct: 3279 KFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFS 3338
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ ++ +I S A + Q T M+ G ++ + I + + G
Sbjct: 3339 QDTYTTVI------SEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRG 3392
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ K LDRE Y +TV A N G V I + D NDN PVF Y I
Sbjct: 3393 EVKVTKLLDRETISGYTLTVQASDN-GSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVII 3451
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN +G + + ++ D+ F + G ++ F+V N V ++ R+
Sbjct: 3452 QENKPVGFSV-LQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEV--NPQGVLLTSSAIKRK 3508
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+K Y L + D G LSS + I + +E+ P +E
Sbjct: 3509 EKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLE 3551
Score = 119 bits (286), Expect = 7e-25
Identities = 123/479 (25%), Positives = 209/479 (43%), Gaps = 42/479 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+E D V + ++D ND+ P F S YE + + T I ++ AVD D +
Sbjct: 1429 VEATDGTTTILTQVFIKVIDTNDHRPQFSTSK-YEVVIPEDTAPETEILQISAVDQD--E 1485
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERR 549
++Y LQ + + F+++P TG++ +E E L V DQ P +R
Sbjct: 1486 KNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQDV-PVKRN 1544
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVS 607
++ VV + T P F + Y+ V + +G+ V Q+ D + +V
Sbjct: 1545 FARIVVNVSDTND------HAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVL 1598
Query: 608 YDLLHGY--EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATV 664
Y + G G F ++ G I +L R N+ YD A + + +S +T+ +
Sbjct: 1599 YSIESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRI 1658
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF-HTNMSSIYGNGTGNVRFLIANQ 723
V ++ +S + S G+ +G + H+ S +Y GN +
Sbjct: 1659 FVTIADNASPKFTSKEYSVELSETV--SIGSFVGMVTAHSQSSVVYEIKDGNT----GDA 1712
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D+ GTI TQK LD E +Y + + G+ + V ++++DENDN
Sbjct: 1713 FDINP-----HSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNT---TVLVHLQDENDN 1764
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDN----IIKATDADEGTNALFMYTLFGEG-KEMFD 838
PVF A Y G I E++ I + + D +I+A DAD+ +NAL +Y + F
Sbjct: 1765 APVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFA 1824
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE--AELIIMIGDENDNKPEF 893
+D +TG + + SLD E+ ++ ++ D G L +E A + + + D ND P F
Sbjct: 1825 IDSSTGAIHTV-LSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVF 1882
Score = 112 bits (270), Expect = 6e-23
Identities = 127/479 (26%), Positives = 201/479 (41%), Gaps = 62/479 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE++ G I++++A D D N +I Y KL+ D E+K ++
Sbjct: 3034 IPEDVLPGKLIMQISATDADIRSNAEITYTLLGSG-AEKFKLNPDTGELKTSTPLDREE- 3091
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
++ + L + A DGG S+ V ++DVND+ P F Y V E
Sbjct: 3092 ----------QAVYHLLVRATDGGGRFCQASIVVTLEDVNDNAPEFSADPYAITVFENTE 3141
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+L +V ATDAD G N + Y + S D F I+ L+G++ + LDRE + Y L+
Sbjct: 3142 PGTLLTRVQATDADAGLNRKILYSLIDS-ADGQFSINELSGIIQLEKPLDRELQAVYTLS 3200
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
+ A D G D+NDN P F E E+ ++++ ++
Sbjct: 3201 LKAVDQGLPRRLTATGTVIVSVLDINDNPPVF----EYREYGATVSEDI----LVGTEVL 3252
Query: 1180 PVYKAT--IEENAPIGTTVAKVFANDTDFIGNGNG--LILYSLPQRKNQQ--------NL 1227
VY A+ IE NA I ++ + I + G I+ +L + + +
Sbjct: 3253 QVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDG 3312
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHY 1285
G PSLS A + V V D+ D + PVF Y I E+ + V V + +
Sbjct: 3313 GTPSLSDVATVNVNVTDIND-----NTPVFSQDTYTTVISEDAVLEQSVITVMADDADGP 3367
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N + Y I++ N +F IDP G + + + DRE Y + V+A P
Sbjct: 3368 SNSHIHYSIIDGNQGS---SFTIDPVRGEVKVTKLLDRETISGYTLTVQAS----DNGSP 3420
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ V + + DVNDN+P F+ GN ++ I P G+ V+QL
Sbjct: 3421 PRVNTTT-------------VNIDVSDVNDNAPVFSRGNYSVI--IQENKPVGFSVLQL 3464
Score = 109 bits (263), Expect = 4e-22
Identities = 129/447 (28%), Positives = 188/447 (42%), Gaps = 30/447 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL S V V+V+L D NDN P F+P N Y ++ + GTVI ++A DPDLGQ+G V
Sbjct: 904 EPQLFSTVVVKVSLEDVNDNPPTFIPPN-YRVKVREDLPEGTVIMWLEAHDPDLGQSGQV 962
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y L F ++ +G V + + E + + L V A D+ S S
Sbjct: 963 RYSLLDHGE----GNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVS--LSSTC 1016
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLL 611
V +EV + P P F + V + +G+ V + + DA ++ Y +
Sbjct: 1017 YVEVEVVDVNENLHP--PVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIR 1074
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVN 670
G GV F + E +GVI D L R + Y A + LS + V DVN
Sbjct: 1075 DGSGVGV-FKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVN 1133
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + P I + F + SS N + N Q
Sbjct: 1134 DNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS---NDKLMYKITSGNPQGFFS-- 1188
Query: 731 AIAEDGTI-FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ G I T + LDRE++D + + V N G + I +V + I DENDN P F
Sbjct: 1189 IHPKTGLITTTSRKLDREQQDEHILEVTVTDN-GSPPKSTIARVIVKILDENDNKPQFLQ 1247
Query: 790 ATYEGFIMENSKIGTE--IKMDNIIK--ATDADEGTNALFMYTL-FGEGKEMFDVDENTG 844
Y+ + E K E + + + + ATD DEG NA Y++ G F ++ TG
Sbjct: 1248 KFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTG 1307
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTG 871
VV S E I LS+ A D G
Sbjct: 1308 VVSSKRFSAAGEYDI---LSIKAVDNG 1331
Score = 109 bits (262), Expect = 6e-22
Identities = 196/795 (24%), Positives = 328/795 (41%), Gaps = 86/795 (10%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F++ +G+I++++ + R ++ E A+ T V V+ N +
Sbjct: 411 FSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKAS----TKVLVKVLGANSNPPEFTQT 466
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAE-DGT 737
A+ EN IG + + G G V + IAN V AI G
Sbjct: 467 AYKAAF---DEN---VPIGTTIMSLSAVDPDEGENGYVTYSIANLNHVP--FAIDHFTGA 518
Query: 738 IFTQKPLDREKRD-VYRMTVIAEFNKGVISGAGIYQV-TIYIEDENDNPPVFEHATYEGF 795
+ T + LD E VY + + A + G+ + + TI + + NDN P+FE EG
Sbjct: 519 VSTSENLDYELMPRVYTLRIRAS-DWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGT 577
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLD 854
I + +G +I + A DADE L Y + G ++F ++ N+GV+ +D
Sbjct: 578 IPRDLGVGEQI---TTVSAIDADE--LQLVQYQIEAGNELDLFSLNPNSGVLSLKRSLMD 632
Query: 855 R--EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
K + L + A D G + L I I +K Q EE ++ E L
Sbjct: 633 GLGAKVSFHSLRITATD--GENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQA 690
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFL--------IPENIPIGTTIIKLNALDLDSGLNG 964
EV+ + V+ P F + EN P+G+++I +N+ DLD+G NG
Sbjct: 691 NKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNG 750
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDG 1022
++ Y + + D+ F+I+ G + + L E+ ++ LNI+ D
Sbjct: 751 KLVYAVSGG--------NEDSC-----FMIDMETGMLKILSPLDRETTDKYTLNITVYDL 797
Query: 1023 GNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
G + V V D ND+ P F + Y V E + + +V+ATD D G N ++
Sbjct: 798 GIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHV 857
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX-XXXXXXXXXX 1139
TY I +DTD F I +TGV+++ LDRE + ++ L + ARD
Sbjct: 858 TYSIL-TDTD-TFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKV 915
Query: 1140 XXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
DVNDN P F ++ ++L +M + + + ++ + ++
Sbjct: 916 SLEDVNDNPPTFIP----PNYRVKVREDLPEGTV--IMWLEAHDPDLGQSGQVRYSLLDH 969
Query: 1200 FAN--DTDFIGNGNGLILYSLPQRKNQQNL-------GLP-SLSSTAILMVTVADVPDEV 1249
D D + ++ ++K NL G P SLSST + V V DV + +
Sbjct: 970 GEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENL 1029
Query: 1250 EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF----KMRYYILNENDTDIRRT 1305
PVF S + ++E +APV + + ++ H E+ ++RY I + + +
Sbjct: 1030 H---PPVFSSFVEKGTVKE--DAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGVGV--- 1081
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM-IYPVAEDVLEGMTKYDV 1364
F I G + DRE Y + V A Q + IY EDV + +
Sbjct: 1082 FKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQ--T 1139
Query: 1365 KVVVRIKDVNDNSPK 1379
V ++ +NSPK
Sbjct: 1140 SEPVYYPEIMENSPK 1154
Score = 98.7 bits (235), Expect = 1e-18
Identities = 91/325 (28%), Positives = 142/325 (43%), Gaps = 24/325 (7%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL------TVP 135
S+ V +EDVNDN P F PY +TV E T G L + +
Sbjct: 3112 SIVVTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSAD 3171
Query: 136 RGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
+I + +KP Y++ + D G ++ V++ VLD +
Sbjct: 3172 GQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIV--SVLDINDNP 3229
Query: 195 KEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
F+ G + ++IL + +A +D+ A + Y +ISGN+ FS+DS G
Sbjct: 3230 PVFE--YREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTG 3287
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
++F+ + LD ++ H + L V+A+ P + A V + + D+NDN P F D Y
Sbjct: 3288 AVFIIENLDYESSHE-----YYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTY 3342
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVL 369
I E+ SV+ VMA D D N Y + D +F+IDP G V+ +L
Sbjct: 3343 TTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRG--EVKVTKLL 3400
Query: 370 DREAHSSLRMKVYAKET-NPSVVGT 393
DRE S + V A + +P V T
Sbjct: 3401 DRETISGYTLTVQASDNGSPPRVNT 3425
Score = 98.3 bits (234), Expect = 1e-18
Identities = 126/474 (26%), Positives = 200/474 (42%), Gaps = 35/474 (7%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
E IE + ++ V V+V + D NDN PVFV Y +K + +VG VI V AVD D
Sbjct: 2055 EVIEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAV-VKVDTEVGHVIRYVTAVDRDS 2113
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPS 546
G+NG V Y L+ F+I P G +S+ E L + + V A D NP+
Sbjct: 2114 GRNGEVHYYLKEHHE-----HFQIGP-LGEISLKKQFELDTLNKEYLVTVVAKDG-GNPA 2166
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV 606
+S V+ + +T K +P F Y + ++ + + V ++ N E V
Sbjct: 2167 ---FSAEVI-VPITVMNKA----MPVFEKPFYSAEIAESIQVHSPVVHVQANSP-EGLKV 2217
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y + G + F + +GVI V+ L P Y A + V
Sbjct: 2218 FYSITDG-DPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIV 2276
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D+ND V + +++ + + G ++ Q+ T+ S G F N
Sbjct: 2277 DDINDNPPVFAQQSYAVTLSEA--SVIGTSVVQVRATDSDSEPNRGISYQMF--GNHSKS 2332
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
D + + G I + LD E+ + + V A + G+ + + VT+ + D N NPP
Sbjct: 2333 HDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRA-VDGGMPTLSSDVIVTVDVTDLNGNPP 2391
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTG 844
+FE YE I E++ G + +KA DAD Y+ L G + F +D TG
Sbjct: 2392 LFEQQIYEARISEHAPHGHFV---TCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATG 2448
Query: 845 VVKFIGDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
++ +L R K Y L+L D G S ++ + + N + P F Q E
Sbjct: 2449 IITL--SNLHRHALKPFYSLNLSVSD-GVFRSSTQVHVTVIGGNLHSPAFLQNE 2499
Score = 96.7 bits (230), Expect = 4e-18
Identities = 125/459 (27%), Positives = 186/459 (40%), Gaps = 64/459 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+P G+ +I++ A D DSG NGQ+ Y + + ++EV F IN G
Sbjct: 2820 IVENLPGGSRVIQIRASDADSGTNGQVMYSLDQ----------SQSVEVIESFAINMETG 2869
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + L E +++ + A D G L+ V V V DVND P F Y V
Sbjct: 2870 WITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTV 2929
Query: 1055 EEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDRE 1111
E V+ + TDAD + N +TYFI D F + + + V LDRE
Sbjct: 2930 SEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDRE 2989
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
D Y+LT+ A D D NDNSP L PE D L
Sbjct: 2990 KRDNYLLTITATDG----TFSSKAIVEVKVLDANDNSP--VCEKTLYSDTIPE-DVLPG- 3041
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
+ +M I A I NA I T+ A + G + S P + +Q +
Sbjct: 3042 --KLIMQISATDADIRSNAEITYTLLGSGAEKFK-LNPDTGELKTSTPLDREEQAVYHLL 3098
Query: 1232 LSST--------AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ +T A ++VT+ DV D + P F + Y + + EN L + T+
Sbjct: 3099 VRATDGGGRFCQASIVVTLEDVND-----NAPEFSADPYAITVFENTEPGTLLTRVQATD 3153
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
N K+ Y +++ D F I+ +G + L + DRE++ Y + ++A Q
Sbjct: 3154 ADAGLNRKILYSLIDSADGQ----FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLP 3209
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
R L G V+V + D+NDN P F
Sbjct: 3210 RRL----------TATG------TVIVSVLDINDNPPVF 3232
Score = 91.9 bits (218), Expect = 1e-16
Identities = 102/388 (26%), Positives = 164/388 (42%), Gaps = 39/388 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+I +GT ++++ A D N +I Y S +S + F I+ + G
Sbjct: 3241 VSEDILVGTEVLQVYAASRDIEANAEITY----------SIISGNE---HGKFSIDSKTG 3287
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V + +L ES E+ L + A DGG +L+D +V V V D+ND+ PVF + Y +
Sbjct: 3288 AVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVIS 3347
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + V A DAD N+++ Y I + F I P+ G + V LDRET
Sbjct: 3348 EDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISG 3407
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADELSNHNF 1173
Y LTV A DNG DVNDN+P F + +++ P F
Sbjct: 3408 YTLTVQASDNG-SPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPV-------GF 3459
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILYSLPQRKNQQNLGLPSL 1232
+ ++ + + P T+ V ND F N G++L S ++ +++
Sbjct: 3460 SVLQLVVTDEDSSHNGPPFFFTI--VTGNDEKAFEVNPQGVLLTSSAIKRKEKD------ 3511
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY 1292
+L V VAD + ++S R E I P+E+ + E Y +
Sbjct: 3512 --HYLLQVKVAD-NGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGK 3568
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRS 1320
+ D T+ +DP+ L+ V S
Sbjct: 3569 IHATDQDVYDTLTYSLDPQMDNLFSVSS 3596
Score = 89.0 bits (211), Expect = 9e-16
Identities = 87/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 67 LVRIGAGL-NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-- 123
L + GL +++A +V V + D+NDN P+F Y TV E G + A
Sbjct: 3201 LKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRD 3260
Query: 124 IGPSLTIPLTVPRG-----LTIFKDIRA-FDRDKPNTPNSDVHYSIVSGNDDGHFALESS 177
I + I ++ G +I A F + + +S +Y V D G +L
Sbjct: 3261 IEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDV 3320
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
+ + + D + + S + ++ + + A D D + + Y +I
Sbjct: 3321 ATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVIT--VMADDADGPSNSHIHYSIID 3378
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN F++D V G + + K LD + + + L VQAS +P + V I++
Sbjct: 3379 GNQGSSFTIDPVRGEVKVTKLLDRET-----ISGYTLTVQASDNGSPPRVNTTTVNIDVS 3433
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE---FTYQLDDPKGAFSI 354
D+NDN P F Y++ I EN P GFSVLQ++ TD+D NG FT + + AF +
Sbjct: 3434 DVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEV 3493
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKV 381
+P+ G L + + H L++KV
Sbjct: 3494 NPQ-GVLLTSSAIKRKEKDHYLLQVKV 3519
Score = 81.8 bits (193), Expect = 1e-13
Identities = 125/482 (25%), Positives = 198/482 (41%), Gaps = 74/482 (15%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E++P+GT I DL IR E + V K + FVI+ +
Sbjct: 2712 FTVSEDVPVGTEI------DL-------IRAEHSGTVLYSLVKGNTPESNRDESFVIDRQ 2758
Query: 998 HGHVIVARSLPPESEFRLNISAL-----DGGNLNDNISVRVFVKDVNDHFPVFKKTWYN- 1051
G + + +SL E+ S L D + ++ V + VKD ND+ PVF+ + Y
Sbjct: 2759 SGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEA 2818
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS---DTDLPFEISPLTGVLSVNGEL 1108
F VE RV+ ++ A+DAD G N + Y + S + F I+ TG ++ EL
Sbjct: 2819 FIVENLPGGSRVI-QIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKEL 2877
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEAD 1166
D E D Y + VVA D+G DVND+ P+F A + + P+
Sbjct: 2878 DHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGG 2937
Query: 1167 E---LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN 1223
LS + +S + I P+G FA +T I N + + R+
Sbjct: 2938 VIAILSTTDADSEEINRQVTYFITGGDPLGQ-----FAVET--IQNEWKVYVKKPLDREK 2990
Query: 1224 QQNLGLP------SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+ N L + SS AI+ V V D D + PV Y I E+V ++
Sbjct: 2991 RDNYLLTITATDGTFSSKAIVEVKVLDAND-----NSPVCEKTLYSDTIPEDVLPGKLIM 3045
Query: 1278 SLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ T+ N ++ Y +L F ++P G L DRE + Y ++VRA
Sbjct: 3046 QISATDADIRSNAEITYTLLGSG----AEKFKLNPDTGELKTSTPLDREEQAVYHLLVRA 3101
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKY-DVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTT 1394
+G ++ +VV ++DVNDN+P+F + + +T T
Sbjct: 3102 --------------------TDGGGRFCQASIVVTLEDVNDNAPEF-SADPYAITVFENT 3140
Query: 1395 AP 1396
P
Sbjct: 3141 EP 3142
Score = 79.8 bits (188), Expect = 5e-13
Identities = 105/458 (22%), Positives = 181/458 (39%), Gaps = 58/458 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P +++++ A D DS N ++ Y+ S + +F I+ + G
Sbjct: 1148 IMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSG-------------NPQGFFSIHPKTG 1194
Query: 1000 HVIV-ARSLPPES--EFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNV 1054
+ +R L E E L ++ D G+ + RV VK D ND+ P F + +Y +
Sbjct: 1195 LITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRL 1254
Query: 1055 EEAQYT-------RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
E + R L +V ATD D G NA ++Y I+ + F I P TGV+S
Sbjct: 1255 PEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRF 1314
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
D IL++ A DNG + + + E+D
Sbjct: 1315 SAAGEYD--ILSIKAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDP 1372
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQ 1224
+++ MI V P+ + + + G G I+ + P ++K+
Sbjct: 1373 VAH-------MIGVISVE-PPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSN 1424
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTE 1283
NL + + T ++ V ++ +D +P F + YE+ I E+ E++ ++ +
Sbjct: 1425 YNLTVEATDGTTTILTQV--FIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVD 1482
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
E K+ Y + + D + F +DP G+LY D E + V Q
Sbjct: 1483 QDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQD---- 1538
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
PV + ++VV + D ND++P FT
Sbjct: 1539 -----VPVKRNF--------ARIVVNVSDTNDHAPWFT 1563
Score = 77.4 bits (182), Expect = 3e-12
Identities = 122/486 (25%), Positives = 201/486 (41%), Gaps = 55/486 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L SF+ + + + D NDN P Y M+++ K +V+ +++A DPD N ++Y
Sbjct: 1119 LSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVV-QIEAFDPDSSSNDKLMYK 1177
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
+ TS F I+P TG ++ + + H L V +D N S + ++A V
Sbjct: 1178 I--TSG-NPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTD---NGSPPKSTIARV 1231
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV---------NDAFEQNDV 606
+++ NKP F+ Y+ + R D ++
Sbjct: 1232 IVKIL-DENDNKPQ---FLQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEI 1287
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP-MYDFEAVALQENANLSIVTNATVH 665
SY + G E G F +E ++GV++ R++ YD ++ +N + +H
Sbjct: 1288 SYSIEDGNEHG-KFFIEPKTGVVSS----KRFSAAGEYDILSIKAVDNGRPQKSSTTRLH 1342
Query: 666 VVDVNDERGVL--LKGAHSPIIFHVKENSAGA-AIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ ++ + L + S F V E+ A IG I S+ G +
Sbjct: 1343 IEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVI------SVEPPGIPLWFDITGG 1396
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
D D+ GTI KPLD E++ Y +TV A I + QV I + D ND
Sbjct: 1397 NYDSHFDVDKGT-GTIIVAKPLDAEQKSNYNLTVEATDGTTTI----LTQVFIKVIDTND 1451
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFD 838
+ P F + YE I E++ TEI I A D DE N L +YTL + F
Sbjct: 1452 HRPQFSTSKYEVVIPEDTAPETEILQ---ISAVDQDE-KNKL-IYTLQSSRDPLSLKKFR 1506
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVAR--DTGGLSSEAELIIMIGDENDNKPEFNQI 896
+D TG + + + LD E L+++ R D + A +++ + D ND+ P F
Sbjct: 1507 LDPATGSL-YTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTAS 1565
Query: 897 EENSKV 902
+V
Sbjct: 1566 SYKGRV 1571
Score = 76.6 bits (180), Expect = 5e-12
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 13/151 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D L Y++ SGN + FS+ G L LD E Q + +L+V
Sbjct: 1161 IEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTG-LITTTSRKLDRE---QQDEHILEVT 1216
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE-NLPN------GFSVLQVMA 330
+ +P K+ ARV +++LD NDN P+F FY I + E P+ + +V+A
Sbjct: 1217 VTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVIA 1276
Query: 331 TDKDQGENGEFTYQLDD--PKGAFSIDPRSG 359
TDKD+G N E +Y ++D G F I+P++G
Sbjct: 1277 TDKDEGPNAEISYSIEDGNEHGKFFIEPKTG 1307
Score = 75.8 bits (178), Expect = 9e-12
Identities = 114/474 (24%), Positives = 189/474 (39%), Gaps = 62/474 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P+G+ ++ ++A D D+G +G+IRY + V F I E G
Sbjct: 1043 VKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRD----------GSGVGV---FKIGEETG 1089
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + L ES + L + A D G L+ I + + V+DVND+ P + Y +
Sbjct: 1090 VIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIM 1149
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG-ELDRETED 1114
E + +++A D D N L Y I + F I P TG+++ +LDRE +D
Sbjct: 1150 ENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQD 1209
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-YAFDELLEWKHPEADELSNHNF 1173
++IL V DNG D NDN P+F F ++ + + D N
Sbjct: 1210 EHILEVTVTDNG-SPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARR 1268
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL---------YSLPQRKNQ 1224
E + + NA I ++ + FI G++ Y + K
Sbjct: 1269 EPLYRVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYDILSIKAV 1328
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPV-FISRYYELEIEENVNAPVELVSLNLTE 1283
N G P SST L + P + S +P+ F ++ + E + PV + ++
Sbjct: 1329 DN-GRPQKSSTTRLHIEWISKP---KQSLEPISFEESFFTFTVME--SDPVAHMIGVISV 1382
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
+ + I N F +D GT+ + + D E K Y + V A
Sbjct: 1383 EPPGIPLWFDITGGN---YDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEA-------- 1431
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP-TTAP 1396
+G T +V +++ D ND+ P+F+ +V IP TAP
Sbjct: 1432 ------------TDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVV--IPEDTAP 1471
Score = 75.8 bits (178), Expect = 9e-12
Identities = 106/478 (22%), Positives = 193/478 (40%), Gaps = 39/478 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + +V++ + ++ +++ F ++Y +K N+ + + A+ + N +
Sbjct: 1959 DGRFAGLTSVKINVKESKESHLKFT-QDVYSAVVKENSTEAETLAVITAIGSPI--NEPL 2015
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y + L FKI+ +G +S +P + EA D E AV
Sbjct: 2016 FYHI-----LNPDRRFKISRTSGVLSTTGTPFDREQQ----EAFDVVVEVIEEHKPSAVA 2066
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
+ V + + P F+ PY V + +G + + D+ +V Y L
Sbjct: 2067 HVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEH 2126
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+E + E S + +L N+ V ++ N + V + +N
Sbjct: 2127 HEHFQIGPLGEIS--LKKQFELDTLNKEY--LVTVVAKDGGNPAFSAEVIVPITVMNKAM 2182
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V K +S I + + + H +S G V + I + +
Sbjct: 2183 PVFEKPFYSAEIAESIQVHS-----PVVHVQANSPEGL---KVFYSITDGDPFSQFTINF 2234
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ-VTIYIEDENDNPPVFEHATY 792
G I PLD E Y++++ A + ++GA V I ++D NDNPPVF +Y
Sbjct: 2235 NTGVINVIAPLDFEAHPAYKLSIRATDS---LTGAHAEVFVDIIVDDINDNPPVFAQQSY 2291
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEMFDVDENTGVVKFI 849
+ E S IGT + ++ATD+D N Y +FG + + F VD +TG++ +
Sbjct: 2292 AVTLSEASVIGTSVVQ---VRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLL 2348
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+LD E+ + + + A D G LSS+ + + + D N N P F Q +++ H
Sbjct: 2349 -RTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQIYEARISEH 2405
Score = 74.9 bits (176), Expect = 2e-11
Identities = 112/473 (23%), Positives = 196/473 (41%), Gaps = 49/473 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK-------VKAVDPDLGQ 491
L + V V L D NDN PVF+ + Y + +A + +V+ ++A D D
Sbjct: 1748 LSTNTTVLVHLQDENDNAPVFMQAE-YTGLISESASINSVVLTDRNVPLVIRAADADKDS 1806
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERR 549
N +++Y + S + + F I+ +TG + S E V+ D
Sbjct: 1807 NALLVYHIVEPS---VHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAE 1863
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQ--NDV 606
Y+ A VT+ V + D P P YE + G V + DA + +
Sbjct: 1864 YA-ANVTVHVI-----DINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQL 1917
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y + G G F+++ ++G +TV + +R +E + + +T+ ++V
Sbjct: 1918 IYSITEG-NIGEKFSMDYKTGALTVQNTTQLRSR----YELTVRASDGRFAGLTSVKINV 1972
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
+ + + +S + VKENS A + + G+ F D
Sbjct: 1973 KESKESHLKFTQDVYSAV---VKENSTEAETLAVI-----TAIGSPINEPLFYHILNPDR 2024
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I+ T P DRE+++ + + V + E +K S V + +ED+NDN P
Sbjct: 2025 RFKISRTSGVLSTTGTPFDREQQEAFDVVVEVIEEHKP--SAVAHVVVKVIVEDQNDNAP 2082
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV---DEN 842
VF + Y + ++++G I+ + A D D G N Y L E E F + E
Sbjct: 2083 VFVNLPYYAVVKVDTEVGHVIR---YVTAVDRDSGRNGEVHYYL-KEHHEHFQIGPLGEI 2138
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ +F D+L++E Y +++VA+D G + AE+I+ I N P F +
Sbjct: 2139 SLKKQFELDTLNKE----YLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEK 2187
Score = 74.9 bits (176), Expect = 2e-11
Identities = 108/436 (24%), Positives = 180/436 (41%), Gaps = 56/436 (12%)
Query: 990 RYFVINERHGHVIVAR----SLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
++FVI+ G + ++ +L P + LN+S DG + V V V N H P F
Sbjct: 2439 KHFVIDSATGIITLSNLHRHALKPF--YSLNLSVSDGV-FRSSTQVHVTVIGGNLHSPAF 2495
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ Y + E ++ +V TD D G ++TY I F I+ + ++
Sbjct: 2496 LQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLE 2555
Query: 1106 GELDRETEDKYILTV--VARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
+LDRET + +++V +A+D G D NDN+P+F A +
Sbjct: 2556 -KLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILT---DDNDNAPQFRATKYEVNIGSS 2611
Query: 1164 EA----------DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
A D N + I +++EN I ++ V IG N
Sbjct: 2612 AAKGTSVVKSASDADEGSNADITYAIEADSESVKENLEINK-LSGVITTKESLIGLENEF 2670
Query: 1214 ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
+ + N G PS S ++ V + +P E+++ P F +Y + E+V
Sbjct: 2671 FTFFVRAVDN----GSPSKESVVLVYVKI--LPPEMQL---PKFSEPFYTFTVSEDVPVG 2721
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRR--TFVIDPRNGTLYLVRSPDREVKDTYEV 1331
E + L EH + + Y ++ N + R +FVID ++G L L +S D E Y+
Sbjct: 2722 TE-IDLIRAEH--SGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQF 2778
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
+ A + E+ VA V V +++KD NDNSP F + P I
Sbjct: 2779 SILARCTQDDHEM------VA----------SVDVSIQVKDANDNSPVFESS--PYEAFI 2820
Query: 1392 PTTAPFGYQVMQLKGA 1407
P G +V+Q++ +
Sbjct: 2821 VENLPGGSRVIQIRAS 2836
Score = 72.9 bits (171), Expect = 6e-11
Identities = 48/180 (26%), Positives = 83/180 (46%), Gaps = 8/180 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G +RY + G+ +F + G + LD ++ + F
Sbjct: 1056 VSAHDEDAGRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQG 1115
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
L++ ++ + IE+ D+NDN P+ Y I+EN P SV+Q+ A D D
Sbjct: 1116 VVPLSSFIE-----IYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSS 1170
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
N + Y++ +P+G FSI P++G +T ++ LDRE ++V + T A
Sbjct: 1171 NDKLMYKITSGNPQGFFSIHPKTGLITTTSRK-LDREQQDEHILEVTVTDNGSPPKSTIA 1229
Score = 71.7 bits (168), Expect = 1e-10
Identities = 102/406 (25%), Positives = 169/406 (41%), Gaps = 58/406 (14%)
Query: 946 IGTTIIKLNALDLDSGLNGQIRY---EFNSEVYIPPSKLSADALEVKRYFVINERHGHVI 1002
+G I + A+D DSG NG++ Y E + I P + +K+ F ++ +
Sbjct: 2099 VGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGP----LGEISLKKQFELDTLN---- 2150
Query: 1003 VARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
E+ + + A DGGN + V V + +N PVF+K +Y+ + E+ +
Sbjct: 2151 --------KEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESI---Q 2199
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
V V A+ + + Y I D F I+ TGV++V LD E Y L++ A
Sbjct: 2200 VHSPVVHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRA 2259
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
D+ D+NDN P F + A LS + ++ V
Sbjct: 2260 TDS--LTGAHAEVFVDIIVDDINDNPPVFA--------QQSYAVTLSEASVIGTSVVQV- 2308
Query: 1183 KATIEENAPIGTTVAKVFAN-----DTDFIGNGNGLI--LYSLPQRKNQQNL-------- 1227
+AT ++ P ++F N D + + GLI L +L +++Q+
Sbjct: 2309 RATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDG 2368
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHY 1285
G+P+LSS I+ V V D+ + P+F + YE I E+ V V +
Sbjct: 2369 GMPTLSSDVIVTVDVTDL-----NGNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSS 2423
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ K++Y IL+ ND + FVID G + L +K Y +
Sbjct: 2424 DIDKLQYSILSGND---HKHFVIDSATGIITLSNLHRHALKPFYSL 2466
Score = 71.3 bits (167), Expect = 2e-10
Identities = 126/552 (22%), Positives = 229/552 (41%), Gaps = 82/552 (14%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT+++K +A D D G N I Y + AD+ VK IN+ G + S
Sbjct: 2615 GTSVVK-SASDADEGSNADITYA-----------IEADSESVKENLEINKLSGVITTKES 2662
Query: 1007 LPP-ESEF-RLNISALDGGNLNDNISVRVFVKDVNDHF--PVFKKTWYNFNVEEAQYTRR 1062
L E+EF + A+D G+ + V V+VK + P F + +Y F V E
Sbjct: 2663 LIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGT 2722
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+ + A + + + S+ D F I +G L + LD ET Y +++A
Sbjct: 2723 EIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILA 2782
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
R D NDNSP FES Y
Sbjct: 2783 RCTQDDHEMVASVDVSIQVKDANDNSPV----------------------FES----SPY 2816
Query: 1183 KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTV 1242
+A I EN P G+ V ++ A+D D NG ++YSL Q ++ + + +++ + T+
Sbjct: 2817 EAFIVENLPGGSRVIQIRASDAD--SGTNGQVMYSLDQSQSVEVIESFAINMETGWITTL 2874
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDI 1302
++ E + + ++ + +I+ + A V++ ++ + F Y ++ D
Sbjct: 2875 KELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDD- 2933
Query: 1303 RRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIY---PVAEDVLEGM 1359
P+ G + ++ + D A+ ++ +R++ + I P+ + +E +
Sbjct: 2934 -------PQGGVIAILSTTD------------ADSEEINRQVTYFITGGDPLGQFAVETI 2974
Query: 1360 TKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQ-VMQLK--GAIGHHPTASR 1416
+ KV V K D + + L+T T F + ++++K A + P +
Sbjct: 2975 QN-EWKVYV--KKPLDREKR----DNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEK 3027
Query: 1417 TVRADT-DELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRV 1475
T+ +DT E V +L + ATD+DI NA+I Y +L A +F ++P +G ++
Sbjct: 3028 TLYSDTIPEDVLPGKL----IMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKT 3083
Query: 1476 VAALARDAGRVF 1487
L R+ V+
Sbjct: 3084 STPLDREEQAVY 3095
Score = 69.3 bits (162), Expect = 8e-10
Identities = 56/179 (31%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
I A+DQD L Y L S D K F LD GSL+ ++LD +A + L
Sbjct: 1478 ISAVDQD--EKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEA-----VSPAHL 1530
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V + P+K AR+ + + D ND+ P F Y + E+ G VLQV A DKD
Sbjct: 1531 TVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKD 1590
Query: 335 QGENGEFTYQLDDPK-----GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
+G+N E Y ++ +F IDP G + + +A L +K K + P
Sbjct: 1591 KGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPP 1649
Score = 67.7 bits (158), Expect = 2e-09
Identities = 93/365 (25%), Positives = 151/365 (41%), Gaps = 45/365 (12%)
Query: 991 YFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFK 1046
+F +++ G +IVA+ L E S + L + A DG I +VF+K D NDH P F
Sbjct: 1401 HFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDG---TTTILTQVFIKVIDTNDHRPQFS 1457
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL---PFEISPLTGVLS 1103
+ Y + E + ++ A D D + L Y +Q S L F + P TG L
Sbjct: 1458 TSKYEVVIPEDTAPETEILQISAVDQD--EKNKLIYTLQSSRDPLSLKKFRLDPATGSLY 1515
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
+ +LD E LTV+ RD D ND++P F
Sbjct: 1516 TSEKLDHEAVSPAHLTVMVRDQ-DVPVKRNFARIVVNVSDTNDHAPWF------------ 1562
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN-GNGL----ILYSL 1218
A +ES + V + G +++ ++ IGN GN +L S+
Sbjct: 1563 TASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSI 1622
Query: 1219 P-----QRKNQ--QNLGLPSLSSTAILMVTVADVPDEVEMSD--KPVFISRYYELEIEEN 1269
R NQ +L + + + M + V V ++D P F S+ Y +E+ E
Sbjct: 1623 KTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSET 1682
Query: 1270 VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
V+ V + +T H ++ + Y I + N D F I+P +GT+ ++ D E Y
Sbjct: 1683 VSIG-SFVGM-VTAHSQS-SVVYEIKDGNTGD---AFDINPHSGTIITQKALDFETLPIY 1736
Query: 1330 EVIVR 1334
+I++
Sbjct: 1737 TLIIQ 1741
Score = 67.7 bits (158), Expect = 2e-09
Identities = 55/193 (28%), Positives = 86/193 (44%), Gaps = 21/193 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P+ T ++++ D DSG+ G + Y ++ K F INER G
Sbjct: 2504 LAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDF-------------AKDRFYINER-G 2549
Query: 1000 HVIVARSL----PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L P E + + A D G +V V + D ND+ P F+ T Y N+
Sbjct: 2550 QIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIG 2609
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETE 1113
+ + K A+DAD G NA++TY I+ + EI+ L+GV++ L
Sbjct: 2610 SSAAKGTSVVK-SASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLEN 2668
Query: 1114 DKYILTVVARDNG 1126
+ + V A DNG
Sbjct: 2669 EFFTFFVRAVDNG 2681
Score = 67.3 bits (157), Expect = 3e-09
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 8/168 (4%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT-----FVLQVQASQLNNPL 285
+RY+++SG+ LF + F + + N + L V+A + N +
Sbjct: 70 VRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNV 129
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A+ +V +++LD ND P F Y++S+ EN S+ +V ATD D G NGEF Y
Sbjct: 130 E-ARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSF 188
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
D F+I P SG + + + LD M++ A + + G+
Sbjct: 189 KDRTDMFAIHPTSGVIVLTGR--LDYLETKLYEMEILAADRGMKLYGS 234
Score = 64.9 bits (151), Expect = 2e-08
Identities = 54/190 (28%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +L AN N P F + Y+ + N +GT I + AVDPD G+NG V Y + ++
Sbjct: 449 VLVKVLGANSNPPEFTQT-AYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIANLNH 507
Query: 505 LTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ PF I+ TG VS +E+ ++ + L + ASD LA +T+
Sbjct: 508 V----PFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITL---- 559
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
+ P F E + ++G+G + + DA E V Y + G E + F+
Sbjct: 560 --NNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDL-FS 616
Query: 622 VEERSGVITV 631
+ SGV+++
Sbjct: 617 LNPNSGVLSL 626
Score = 64.5 bits (150), Expect = 2e-08
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 9/159 (5%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D A L Y ++ + F++DS G++ LD + + + F
Sbjct: 1794 PLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYE-----ETSIFHF 1848
Query: 275 QVQASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VQ + P A+ A V + ++D+ND P F Y S++ G V+ V ATD
Sbjct: 1849 TVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATD 1908
Query: 333 KDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVL 369
D + Y + + FS+D ++G LTV+N T L
Sbjct: 1909 ADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQL 1947
Score = 64.1 bits (149), Expect = 3e-08
Identities = 40/118 (33%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Query: 1010 ESEFRLNISALDGG-NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+ + L + AL+ N+ VRV V D ND P+F T Y+ ++ E R + +V
Sbjct: 113 KDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVS 172
Query: 1069 ATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
ATDAD G N Y+ TD+ F I P +GV+ + G LD Y + ++A D G
Sbjct: 173 ATDADIGTNGEF-YYSFKDRTDM-FAIHPTSGVIVLTGRLDYLETKLYEMEILAADRG 228
Score = 62.5 bits (145), Expect = 9e-08
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 13/171 (7%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G L +++ GN F +D G++ + K LD + + N + L V+A+ + T
Sbjct: 1386 GIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSN-----YNLTVEATDGTTTILT 1440
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD- 346
+V I+++D ND+ P+F Y + I E+ +LQ+ A D+D+ +T Q
Sbjct: 1441 ---QVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSR 1497
Query: 347 DPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
DP F +DP +G L + LD EA S + V ++ + V FA
Sbjct: 1498 DPLSLKKFRLDPATGSLYTSEK--LDHEAVSPAHLTVMVRDQDVPVKRNFA 1546
Score = 62.5 bits (145), Expect = 9e-08
Identities = 114/473 (24%), Positives = 183/473 (38%), Gaps = 59/473 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPE+ T I++++A+D D E N +Y S S D L +K+ F ++
Sbjct: 1464 VIPEDTAPETEILQISAVDQD---------EKNKLIYTLQS--SRDPLSLKK-FRLDPAT 1511
Query: 999 GHVIVARSLPPE--SEFRLNISALDGG-NLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + L E S L + D + N + + V V D NDH P F + Y V
Sbjct: 1512 GSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRV 1571
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQP---SDTDLPFEISPLTGVLSVNGELDRE 1111
E+ V+ +V A D D G+NA + Y I+ + F I P+ G + ELDR
Sbjct: 1572 YESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKELDRS 1631
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN-SPKFYAFDELLEWKHPEADELSN 1170
+ +Y L V A D G + DN SPKF + + +E ++ +S
Sbjct: 1632 NQAEYDLMVKATDKGSPPMSEITSVRIFVT--IADNASPKFTSKEYSVEL----SETVSI 1685
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGL 1229
+F ++ + + E T A + I L +LP Q +
Sbjct: 1686 GSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNM 1745
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA-PVELVSLNL------- 1281
LS+ ++V + D E + PVF+ Y I E+ + V L N+
Sbjct: 1746 AGLSTNTTVLVHLQD-----ENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAA 1800
Query: 1282 -TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ N + Y+I+ + + F ID G ++ V S D E + V Q +
Sbjct: 1801 DADKDSNALLVYHIV---EPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTV----QVH 1853
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
P + +Y V V + D+ND P F +PT
Sbjct: 1854 DMGTPRL-----------FAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPT 1895
Score = 60.5 bits (140), Expect = 3e-07
Identities = 65/277 (23%), Positives = 125/277 (45%), Gaps = 27/277 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA-FIFLI-APIGPSLTIPLTVPR 136
A++ V V +ED NDN P+F++ PY+ V T G ++ + G + + +
Sbjct: 2066 AHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKE 2125
Query: 137 GLTIFK-----DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH-KPVLLLRKVLDY 190
F+ +I + + +T N + ++V+ D G+ A + P+ ++ K +
Sbjct: 2126 HHEHFQIGPLGEISLKKQFELDTLNKEYLVTVVA-KDGGNPAFSAEVIVPITVMNKAMP- 2183
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+K F +A ++H P+ + + G + Y + G+ F+++
Sbjct: 2184 -VFEKPFYSAEIAESIQVHS------PVVHVQANSPEGLKVFYSITDGDPFSQFTINFNT 2236
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL--DLNDNLPEFEV 308
G + + LD +A + L ++A+ + L A A V ++++ D+NDN P F
Sbjct: 2237 GVINVIAPLDFEAHP-----AYKLSIRAT---DSLTGAHAEVFVDIIVDDINDNPPVFAQ 2288
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
Y +++ E G SV+QV ATD D N +YQ+
Sbjct: 2289 QSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQM 2325
Score = 60.5 bits (140), Expect = 3e-07
Identities = 77/333 (23%), Positives = 135/333 (40%), Gaps = 68/333 (20%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+ G+ +S+ + VTV + D+N N P+F Y + E P G F+
Sbjct: 2366 VDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQIYEARISEHAPHGH----FVTC------- 2414
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS---------HKP 180
++A+D D + + YSI+SGND HF ++S+ H+
Sbjct: 2415 --------------VKAYDADSSDIDK--LQYSILSGNDHKHFVIDSATGIITLSNLHRH 2458
Query: 181 VLLLRKVLDYDAGDKEF----QLVIMASGKRIHK----------EILFPEPIHAI----- 221
L L+ D F Q+ + G +H E+ P+H +
Sbjct: 2459 ALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVK 2518
Query: 222 --DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
D D G+ + Y +++ + F ++ G +F ++LD + V+ V+
Sbjct: 2519 TTDGDSGIYGHVTYHIVNDFAKDRFYINE-RGQIFTLEKLDRETPAEK-----VISVRLM 2572
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ K A V + L D NDN P+F Y ++I + G SV++ A+D D+G N
Sbjct: 2573 AKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SASDADEGSNA 2631
Query: 340 EFTYQL----DDPKGAFSIDPRSGWLTVRNQTV 368
+ TY + + K I+ SG +T + +
Sbjct: 2632 DITYAIEADSESVKENLEINKLSGVITTKESLI 2664
Score = 59.3 bits (137), Expect = 8e-07
Identities = 99/452 (21%), Positives = 183/452 (40%), Gaps = 45/452 (9%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P+ + + F++ + V +IG + P + + +D+ + S F ++
Sbjct: 1355 PISFEESFFTFTVMESDPVAHMIGVISVEPPGIP----LWFDI---TGGNYDSHFDVDKG 1407
Query: 517 TGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
TGT+ VA+ E + + L VEA+D L V I+V T ++P F
Sbjct: 1408 TGTIIVAKPLDAEQKSNYNLTVEATDGTTT------ILTQVFIKVI-DTNDHRPQ---FS 1457
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE--EGVPFAVEERSGVITVV 632
+ YE + + T + QI D E+N + Y L + F ++ +G +
Sbjct: 1458 TSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTS 1517
Query: 633 DDLSRYN-RPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN 691
+ L P + V Q+ V+V D ND ++ ++ +
Sbjct: 1518 EKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVY--ESA 1575
Query: 692 SAGAAIGQIFHT------NMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
+ G+ + Q+ N +Y +GN+ + + D + G+I T K LD
Sbjct: 1576 AVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNI--GNSFMIDPVL----GSIKTAKELD 1629
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
R + Y + V A +KG + I V I++ ++ P F Y + E IG+
Sbjct: 1630 RSNQAEYDLMVKAT-DKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSF 1688
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ M A ++ ++ G + FD++ ++G + +LD E +Y L +
Sbjct: 1689 VGM------VTAHSQSSVVYEIK-DGNTGDAFDINPHSGTI-ITQKALDFETLPIYTLII 1740
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ GLS+ +++ + DENDN P F Q E
Sbjct: 1741 QGTNMAGLSTNTTVLVHLQDENDNAPVFMQAE 1772
Score = 56.0 bits (129), Expect = 7e-06
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 15/177 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L+Y ++SGND K F +DS G + L H L+ + L +
Sbjct: 2415 VKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNL----HRHALKP-FYSLNLS 2469
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
S + + + +V + ++ N + P F + Y + + EN P V++V TD D G
Sbjct: 2470 VS---DGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGI 2526
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE--AHSSLRMKVYAKETNPSV 390
G TY + D K F I+ R T+ LDRE A + +++ AK+ V
Sbjct: 2527 YGHVTYHIVNDFAKDRFYINERGQIFTLEK---LDRETPAEKVISVRLMAKDAGGKV 2580
Score = 54.8 bits (126), Expect = 2e-05
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 4/100 (4%)
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
++ V+V V+D ND+ PVF Y V+ V+ V A D D G+N + Y+++
Sbjct: 2067 HVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEH 2126
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDK-YILTVVARDNG 1126
F+I PL G +S+ + + +T +K Y++TVVA+D G
Sbjct: 2127 HEH--FQIGPL-GEISLKKQFELDTLNKEYLVTVVAKDGG 2163
Score = 54.4 bits (125), Expect = 2e-05
Identities = 44/153 (28%), Positives = 68/153 (44%), Gaps = 11/153 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D + Y++ + + F +DS G + L + LD E + Q FV
Sbjct: 2308 VRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDY--EQSRQHTIFVRA 2365
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V P ++ V +++ DLN N P FE Y I E+ P+G V V A D D
Sbjct: 2366 VDGGM---PTLSSDVIVTVDVTDLNGNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADS 2422
Query: 336 GENGEFTYQL---DDPKGAFSIDPRSGWLTVRN 365
+ + Y + +D K F ID +G +T+ N
Sbjct: 2423 SDIDKLQYSILSGNDHK-HFVIDSATGIITLSN 2454
Score = 53.6 bits (123), Expect = 4e-05
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 11/130 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
LRY + FSL+ G + + L+ QA F L+V S + A
Sbjct: 398 LRYVFKRTPGKAKFSLNYNTGLISI-----LEPVKRQQAAHFELEVTTSD-----RKAST 447
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+V +++L N N PEF Y + EN+P G +++ + A D D+GENG TY + +
Sbjct: 448 KVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIANLNH 507
Query: 351 A-FSIDPRSG 359
F+ID +G
Sbjct: 508 VPFAIDHFTG 517
Score = 50.8 bits (116), Expect = 3e-04
Identities = 94/487 (19%), Positives = 192/487 (39%), Gaps = 56/487 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ +V + + A++ +P F S Y + +G+ +G V A V+Y+
Sbjct: 1650 MSEITSVRIFVTIADNASPKFT-SKEYSVELSETVSIGSFVGMVTA-----HSQSSVVYE 1703
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
++ + F INP++GT+ ++ E + L ++ ++ + V
Sbjct: 1704 IKDGNT---GDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTN-----TTVL 1755
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ-------IRVNDAFEQNDVSYD 609
+ + + + P FM A Y + + I + V IR DA + ++
Sbjct: 1756 VHL----QDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALL- 1810
Query: 610 LLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI----VTNAT 663
+ H E V FA++ +G I V L ++ F V + + + N T
Sbjct: 1811 VYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHF-TVQVHDMGTPRLFAEYAANVT 1869
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
VHV+D+ND V K + + ++ N + + + + I +
Sbjct: 1870 VHVIDINDCPPVFAKPLYEASLLLPTYKGV-----KVITVNATDADSSAFSQLIYSIT-E 1923
Query: 724 QDVTDDIAIA-EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
++ + ++ + G + Q R Y +TV A + AG+ V I +++ +
Sbjct: 1924 GNIGEKFSMDYKTGALTVQNTTQLRSR--YELTVRASDGRF----AGLTSVKINVKESKE 1977
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
+ F Y + ENS TE + +I A + N Y + + F +
Sbjct: 1978 SHLKFTQDVYSAVVKENS---TEAETLAVITAIGSP--INEPLFYHILNPDRR-FKISRT 2031
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII--MIGDENDNKPEFNQIEENS 900
+GV+ G DRE++ + + + + S+ A +++ ++ D+NDN P F + +
Sbjct: 2032 SGVLSTTGTPFDREQQEAFDVVVEVIEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYA 2091
Query: 901 KVRIHRE 907
V++ E
Sbjct: 2092 VVKVDTE 2098
Score = 50.0 bits (114), Expect = 5e-04
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 6/76 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD ND P+F P++ Y S+ N + T I +V A D D+G NG Y + ++
Sbjct: 135 VRVQVLDTNDLRPLFSPTS-YSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTD 193
Query: 505 LTITSPFKINPNTGTV 520
+ F I+P +G +
Sbjct: 194 M-----FAIHPTSGVI 204
Score = 50.0 bits (114), Expect = 5e-04
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 27/161 (16%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG+P ++ +L V V D D + P F+ Y +E+ E+ E++ + T+
Sbjct: 796 DLGIPQKAAWRLLHVVVVDAND-----NPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD 850
Query: 1286 --ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
N + Y IL + DT F ID G + + R DRE++ + + + A Q +RE
Sbjct: 851 LGPNGHVTYSILTDTDT-----FSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ--ARE 903
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
P + V V V ++DVNDN P F N
Sbjct: 904 EPQLFSTVV-------------VKVSLEDVNDNPPTFIPPN 931
Score = 49.2 bits (112), Expect = 9e-04
Identities = 89/358 (24%), Positives = 139/358 (38%), Gaps = 26/358 (7%)
Query: 25 RDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL---VRI-GAGLNQISAY 80
+D N V I+ S+ + DS + L D++E V++ G ++ A
Sbjct: 1804 KDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAE 1863
Query: 81 LS--VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS----LTIPLTV 134
+ VTV++ D+ND P+F Y ++ T G K S L +T
Sbjct: 1864 YAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITE 1923
Query: 135 PR-GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
G D + NT Y + DG FA +S K + K ++
Sbjct: 1924 GNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASDGRFAGLTSVKINVKESK----ESH 1979
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
K Q V A K E I AI + L Y +++ + R F + +G L
Sbjct: 1980 LKFTQDVYSAVVKENSTEAETLAVITAIGSP--INEPLFYHILNPDRR--FKISRTSGVL 2035
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYN 312
D E Q F + V+ + + P A V++ + D NDN P F + +Y
Sbjct: 2036 STTGT-PFDRE---QQEAFDVVVEVIEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYA 2091
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
+ V+ G + V A D+D G NGE Y L + F I P G ++++ Q LD
Sbjct: 2092 VVKVDT-EVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGP-LGEISLKKQFELD 2147
Score = 49.2 bits (112), Expect = 9e-04
Identities = 43/169 (25%), Positives = 82/169 (48%), Gaps = 12/169 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G + Y L ++ F + + G + L+K+ +LD + +++ V
Sbjct: 2106 VTAVDRDSGRNGEVHYYLKEHHEH--FQIGPL-GEISLKKQFELDTLNK----EYLVTVV 2158
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A NP +A+ V I ++ N +P FE FY+ I E++ V+ V A + +G
Sbjct: 2159 AKDGGNPAFSAEVIVPITVM--NKAMPVFEKPFYSAEIAESIQVHSPVVHVQA-NSPEGL 2215
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
++ DP F+I+ +G + V LD EAH + ++ + A ++
Sbjct: 2216 KVFYSITDGDPFSQFTINFNTGVINV--IAPLDFEAHPAYKLSIRATDS 2262
Score = 46.4 bits (105), Expect = 0.006
Identities = 95/403 (23%), Positives = 151/403 (37%), Gaps = 55/403 (13%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G +I +NA D DS Q+ Y + F ++ + G + V +
Sbjct: 1898 GVKVITVNATDADSSAFSQLIYSITEG-------------NIGEKFSMDYKTGALTVQNT 1944
Query: 1007 LPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
S + L + A DG SV++ VK+ + F + Y+ V+E L
Sbjct: 1945 TQLRSRYELTVRASDG-RFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAV 2003
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG-ELDRETEDKYILTVVARDN 1125
+ A G N F + D F+IS +GVLS G DRE ++ + + V +
Sbjct: 2004 ITA----IGSPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVIEE 2059
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKF-----YAFDEL-LEWKH-----PEADELSNHNFE 1174
D NDN+P F YA ++ E H D S N E
Sbjct: 2060 -HKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGE 2118
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
+ Y E+ IG + ++ + N L ++ + G P+ S+
Sbjct: 2119 ----VHYYLKEHHEHFQIG-PLGEISLKKQFELDTLNKEYLVTVVAKDG----GNPAFSA 2169
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRY 1292
I+ +TV + PVF +Y EI E+ V++PV V N E K+ Y
Sbjct: 2170 EVIVPITVMN-------KAMPVFEKPFYSAEIAESIQVHSPVVHVQANSP---EGLKVFY 2219
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
I D D F I+ G + ++ D E Y++ +RA
Sbjct: 2220 SI---TDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRA 2259
Score = 44.4 bits (100), Expect = 0.024
Identities = 59/244 (24%), Positives = 104/244 (42%), Gaps = 16/244 (6%)
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA- 693
L+R + Y AL++N N+ T V V+D ND R + ++S + EN+A
Sbjct: 108 LNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYS---VSLPENTAI 164
Query: 694 GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVY 752
+I ++ T+ + I NG F +D TD AI G I LD + +Y
Sbjct: 165 RTSIARVSATD-ADIGTNGEFYYSF-----KDRTDMFAIHPTSGVIVLTGRLDYLETKLY 218
Query: 753 RMTVI-AEFNKGVISGAGI---YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
M ++ A+ + +GI ++T++IE N+ PV T ++ + +
Sbjct: 219 EMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIVTV 278
Query: 809 DNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV-VKFIGDSLDREKKIMYKLSLVA 867
D+ + + D + ++ L + + + + VK IGD Y L+L A
Sbjct: 279 DDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQA 338
Query: 868 RDTG 871
+D G
Sbjct: 339 KDKG 342
Score = 39.5 bits (88), Expect = 0.69
Identities = 18/52 (34%), Positives = 32/52 (61%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
LT QATD+D G+N I Y +++ +F+I+ +SG +++ L R+ V+
Sbjct: 3146 LTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVY 3197
Score = 39.1 bits (87), Expect = 0.92
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKF-ALDVDQLGPLFL-------IPENIPIGTTI 950
N +V+ H + T +E + K + LD + L PLF +PEN I T+I
Sbjct: 109 NREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSI 168
Query: 951 IKLNALDLDSGLNGQIRYEF 970
+++A D D G NG+ Y F
Sbjct: 169 ARVSATDADIGTNGEFYYSF 188
Score = 39.1 bits (87), Expect = 0.92
Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 21/233 (9%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
YE+ GN F ++ +G++ +K LD + L T ++Q N + V
Sbjct: 1702 YEIKDGNTGDAFDINPHSGTIITQKALDFE---TLPIYTLIIQ----GTNMAGLSTNTTV 1754
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ-------VMATDKDQGENGEFTYQL 345
+ L D NDN P F Y I E+ VL + A D D+ N Y +
Sbjct: 1755 LVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHI 1814
Query: 346 DDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFAD--SQRI 400
+P F+ID +G + LD E S V + P + +A + +
Sbjct: 1815 VEPSVHTYFAIDSSTG--AIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHV 1872
Query: 401 AKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
P PL + + + P G K + D +F + ++ + N
Sbjct: 1873 IDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGN 1925
Score = 37.1 bits (82), Expect = 3.7
Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 14/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D + L Y + GN + FS+D G+L ++ L + + L V+
Sbjct: 1904 VNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSRYE-------LTVR 1956
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS T+ V+I + + ++ +F D Y+ + EN ++ + A E
Sbjct: 1957 ASDGRFAGLTS---VKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGSPINE 2013
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV-YAKETNPSVV 391
Y + +P F I SG L+ T DRE + + V +E PS V
Sbjct: 2014 --PLFYHILNPDRRFKISRTSGVLSTTG-TPFDREQQEAFDVVVEVIEEHKPSAV 2065
Score = 36.7 bits (81), Expect = 4.9
Identities = 16/48 (33%), Positives = 28/48 (58%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+A D D+G + +RY +L+ F +D +SG VR+V L + +V+
Sbjct: 950 EAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQVY 997
Score = 36.3 bits (80), Expect = 6.5
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
+ATD D+G N + Y IL + F+ID V+G V + L R+
Sbjct: 845 EATDKDLGPNGHVTYSILTD-TDTFSIDSVTGVVNIARPLDRE 886
>UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2270
Score = 155 bits (377), Expect = 7e-36
Identities = 231/956 (24%), Positives = 384/956 (40%), Gaps = 96/956 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A++ + G+++ Y L D F + S +G +F+ LD + + + ++L V
Sbjct: 448 VRALNTEASGGSSISYHLRPDGDAAGFGIMSDSGWIFVRSSLDREVK-----DMYLLTVL 502
Query: 278 ASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +T A V + + D NDN P + +++ ENL G +V A D+D G
Sbjct: 503 ASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERVFLAVRENLLAGTGFGRVSAIDRDAG 562
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMK--VYAKETNPSVVGTF 394
N TY+L F I+ ++G + + + +E HSS+R++ ++ N F
Sbjct: 563 LNARLTYKLLHTDRHFQINSQTGKIIIPITDI--KELHSSIRVQLLIFIPVRNLLNYVLF 620
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
+ + T L++ V + + +T+LD ND
Sbjct: 621 KPNLLCLSSTSGEISTRLALDREHQSSYQLVVVVQDG---GTPPRSATGTAHITVLDEND 677
Query: 455 NNPVFV---PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
N P F P + GTV+G V A DPD G+NG V Y L F
Sbjct: 678 NAPTFSHTRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLSGAR----AERF 733
Query: 512 KINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN-KPDI 570
+NP TG + A SP+ + + + S S + I+V + N KP+I
Sbjct: 734 TLNPMTGELKAA-SPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSNLKPNI 792
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
E ++ IG+ Q + + V+Y ++ G + F V+ G +
Sbjct: 793 FSVTMNAVEGAPPGSI-IGSVRSQNHQQSSSTEGQVTYLVVGGSDRDGTFMVDRLKGDVY 851
Query: 631 VVDDLS--RYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
+V +L + +R E + S + ++V D ND + P+ +
Sbjct: 852 LVRELDYEKGSRYTLHIEVSDFSQAFPSSHLVQLEINVQDRNDHAPHFTE---DPVTIVI 908
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE----DGTIFTQKPL 744
EN+ A F +I +G+G LI + + + + G + + L
Sbjct: 909 PENTEPGASVYTFQ----AIDKDGSGPNSELIYSIEHYWPETHLLSLDPVSGVLTLGQKL 964
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVT--IYIEDENDNPPVFEHATYEGFIMENSKI 802
DRE + V A S VT +++ DENDN PVF + +ME+ +
Sbjct: 965 DRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVFSSPSAVS-VMEDQPV 1023
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
G I + A D DEG N Y + G F ++ NTG + + +LDRE++ ++
Sbjct: 1024 GFVILY---VMARDEDEGENGRVSYRIQAGNTAGRFSLNPNTGSLSIL-KALDREEQEVF 1079
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTII 919
L++VA D G LS+ L + + D ND P F + E + V E K GT T++
Sbjct: 1080 NLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALV---IENKGPGT---TVL 1133
Query: 920 EVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
+V A+D DQ ++ G + ++ +G+ + E ++E
Sbjct: 1134 KVT-----AVDRDQGS-----NGHVTYGGVTEEGFVINPVTGVITTTK-ELDTEA---QD 1179
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFV 1035
+ A + F ++ G + +R L E +E+ L + A D G+ L+ + V+V V
Sbjct: 1180 HYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRGSPALSTTVMVQVQV 1239
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
DVND+ P+F +AD N YF+ D F +
Sbjct: 1240 MDVNDNSPIF-------------------------NADDALNGKFLYFLS-QDAHGAFTV 1273
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TGV++ + LDRE Y V A D DVNDN+P F
Sbjct: 1274 DENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVF 1329
Score = 148 bits (358), Expect = 1e-33
Identities = 178/707 (25%), Positives = 292/707 (41%), Gaps = 46/707 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V+++D NDN P F P LY S+ +++ GT + KV A DPD G NG V Y
Sbjct: 87 LSSVARVRVSVVDINDNRPAFYPV-LYTVSLSTHSSPGTSVVKVTANDPDSGLNGRVTY- 144
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
RT ++ F +N +TG +S++ S + + +E + + A V
Sbjct: 145 --RTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAAEDGGG-----LTAPVNAR 197
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V G P F A Y F V +V GTS+G +R A + S D+L+ G
Sbjct: 198 VNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVR---ASAKTGGSKDILYSISSGD 254
Query: 619 P---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
P F V+ +G I L + E A T + + D+ND
Sbjct: 255 PYGYFTVDSSTGTIRTALPLDHETCSSLELEIQARYGFPPAYGTTRVRITISDINDNAPA 314
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
L + ++ + G I I T+ S + NG + + A + D
Sbjct: 315 FLPSSSESLLL-PEITKMGTVIYTIQATDRDSGH-NGQLSFDLVSAGAAGSSGQRTFGVD 372
Query: 736 ---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + L E Y + V+A+ + G + + + ++I+ ++ P F+ TY
Sbjct: 373 RGSGEVRLIGSLSYESVPRYDLQVVAK-DGGAPQLSSTFTLVVHIQAQDARGPNFDTLTY 431
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGD 851
+ EN+ + T+ ++A + + + Y L +G F + ++G + F+
Sbjct: 432 RVELRENTPLNTQFLQ---VRALNTEASGGSSISYHLRPDGDAAGFGIMSDSGWI-FVRS 487
Query: 852 SLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
SLDRE K MY L+++A G + A + + + DENDN P +Q E + + RE
Sbjct: 488 SLDREVKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQ--ERVFLAV-REN 544
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD-SGLNGQIR 967
L GT GF + ++ L+ L + I + K+ D L+ IR
Sbjct: 545 LLAGT-GFGRVSAIDRDA-GLNARLTYKLLHTDRHFQINSQTGKIIIPITDIKELHSSIR 602
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN- 1024
+ ++IP L L ++ G + +L E S ++L + DGG
Sbjct: 603 VQL--LIFIPVRNLLNYVLFKPNLLCLSSTSGEISTRLALDREHQSSYQLVVVVQDGGTP 660
Query: 1025 -LNDNISVRVFVKDVNDHFPVFKKTWYN----FNVEEAQYTRRVLGKVDATDADFGQNAN 1079
+ + + V D ND+ P F T + V E + VLG V A D D G+N
Sbjct: 661 PRSATGTAHITVLDENDNAPTFSHTRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGT 720
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ Y + + + F ++P+TG L L +Y V A D+G
Sbjct: 721 VHYSLSGARAE-RFTLNPMTGELKAASPLRWAERSEYTFMVTAADHG 766
Score = 100 bits (240), Expect = 3e-19
Identities = 151/667 (22%), Positives = 282/667 (42%), Gaps = 53/667 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQR 501
V +E+ + D ND+ P F + + N + G + +A+D D G N ++Y ++
Sbjct: 883 VQLEINVQDRNDHAPHFTEDPV-TIVIPENTEPGASVYTFQAIDKDGSGPNSELIYSIEH 941
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEV 559
T ++P +G +++ + E +LF V A+DQ +PS+RR+ + V
Sbjct: 942 Y--WPETHLLSLDPVSGVLTLGQKLDRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFV 999
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEG 617
T ++ D +P V + +G + + R D E VSY + G G
Sbjct: 1000 T-----DENDNTPVFSSPSAVSVMEDQPVGFVILYVMARDEDEGENGRVSYRIQAGNTAG 1054
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F++ +G ++++ L R + +++ VA LS +V V+DVNDE V
Sbjct: 1055 -RFSLNPNTGSLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVF 1113
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ ++ ++ G + ++ T + G+ G+V + ++ + G
Sbjct: 1114 QRAEFEALV--IENKGPGTTVLKV--TAVDRDQGSN-GHVTYGGVTEEGF---VINPVTG 1165
Query: 737 TIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH-ATYEG 794
I T K LD E +D Y +T + + + G + ++ E E A+ G
Sbjct: 1166 VITTTKELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRG 1225
Query: 795 FIMENSKIGTEIKMDNIIKAT---DADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
++ + ++++ ++ + +AD+ N F+Y L + F VDENTGV+
Sbjct: 1226 SPALSTTVMVQVQVMDVNDNSPIFNADDALNGKFLYFLSQDAHGAFTVDENTGVIT-TSA 1284
Query: 852 SLDREKKIMYKLSLVARDTGGL---SSEAELIIMIGDENDNKPEFNQ--------IEENS 900
+LDREK Y + A D ++ A++ + + D NDN P F Q I +
Sbjct: 1285 ALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVFIQDPLVIEVSIRHSQ 1344
Query: 901 KV--RIHRETKLNGTAGFTIIE-VKPKNKFALD--VDQLGPLFLIPENIPIGTTIIKLNA 955
+V + E K G G P F+++ ++ + + T+I + A
Sbjct: 1345 RVLATMKAEDKDFGANGSVFYRFATPVKGFSINSLTGEIQATEPLQDLTQAQRTLI-VEA 1403
Query: 956 LDLDSGLNGQ--IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIV--ARSLPPES 1011
+D S + + EV + S +A +V N G ++V ++ L E
Sbjct: 1404 MDQGSPAQSAQGVVVIYVKEVVYNGIRFSRNARDVS--IQENAAKGEIMVQSSKGLDFED 1461
Query: 1012 EFRLN-ISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
RL + + + +++ + ++DVND+ P F+ Y + EAQ + +V A
Sbjct: 1462 TPRLRLVVKAESVSSTSFMAINLILQDVNDNLPRFQLQNYIAYMREAQGYDMPIIQVVAE 1521
Query: 1071 DADFGQN 1077
D D GQN
Sbjct: 1522 DVDQGQN 1528
Score = 77.0 bits (181), Expect = 4e-12
Identities = 59/216 (27%), Positives = 93/216 (43%), Gaps = 12/216 (5%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+PE +GT I + A D DSG NGQ+ ++ S A +R F ++
Sbjct: 324 LLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVSA--------GAAGSSGQRTFGVDRGS 375
Query: 999 GHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G V + SL ES + L + A DGG L+ ++ V ++ + P F Y +
Sbjct: 376 GEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQDARGPNFDTLTYRVEL 435
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E +V A + + ++++Y ++P F I +G + V LDRE +D
Sbjct: 436 RENTPLNTQFLQVRALNTEASGGSSISYHLRPDGDAAGFGIMSDSGWIFVRSSLDREVKD 495
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y+LTV+A D NDNSP+
Sbjct: 496 MYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPR 531
Score = 64.9 bits (151), Expect = 2e-08
Identities = 49/180 (27%), Positives = 77/180 (42%), Gaps = 13/180 (7%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+ +++A D D G G + Y S P D F I++ G + + L
Sbjct: 19 LAQVSATDEDRGSFGAVTYALGS----PSGNTPPDQ------FTIDKGSGQLCTSTPLDR 68
Query: 1010 ES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
+ +F L ++A DGG L+ VRV V D+ND+ P F Y ++ + K
Sbjct: 69 DEGADKFDLTVTATDGGGLSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVK 128
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
V A D D G N +TY P F ++ TGV+S++ L + + + A D G
Sbjct: 129 VTANDPDSGLNGRVTYRTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAAEDGG 188
Score = 62.1 bits (144), Expect = 1e-07
Identities = 51/173 (29%), Positives = 87/173 (50%), Gaps = 13/173 (7%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D+D G + Y L SGN F++D +G L LD D A+ F L
Sbjct: 22 VSATDEDRGSFGAVTYALGSPSGNTPPDQFTIDKGSGQLCTSTPLDRDEG----ADKFDL 77
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A+ ++ ARV + ++D+NDN P F Y +S+ + G SV++V A D D
Sbjct: 78 TVTATDGGG--LSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPD 135
Query: 335 QGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG TY+ G+ F+++ +G +++ L +A++ + M++ A++
Sbjct: 136 SGLNGRVTYRTVPGGGSAFFTLNKDTGVISLSRS--LHGKANTVISMEIAAED 186
Score = 61.7 bits (143), Expect = 2e-07
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 12/179 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQV 276
+ A D D G+ + Y + G F+L+ G + L + L H +ANT + +++
Sbjct: 129 VTANDPDSGLNGRVTYRTVPGGGSAFFTLNKDTGVISLSRSL-----HG-KANTVISMEI 182
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A ARV + ++ + P FE Y ++ E++ G S+ V A+ K G
Sbjct: 183 AAEDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRASAKTGG 242
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+ Y + DP G F++D +G T+R LD E SSL +++ A+ P GT
Sbjct: 243 SK-DILYSISSGDPYGYFTVDSSTG--TIRTALPLDHETCSSLELEIQARYGFPPAYGT 298
Score = 58.8 bits (136), Expect = 1e-06
Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 25/259 (9%)
Query: 382 YAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQ-LM 440
Y+ + +P+ +G F R +W L L++ + T T I+ D Q
Sbjct: 1590 YSLQLDPTALGMFG-IHRYNQWSGA-LRLQRALDR------EHQSTHTVIIQATDGQGHF 1641
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-L 499
+ V V + D NDN+P F P + S++ N + + + A+D D G G + Y L
Sbjct: 1642 ALAPVVVEVKDVNDNHPFF-PVEVLTASIRENQPANSAVTVLHAIDHDTGVFGHLKYFML 1700
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLAVVTIE 558
+RT T F ++PN+G + E ++ FV + N S A VT++
Sbjct: 1701 ERTG--TGKESFSVDPNSGEIRSKIPFDFEKINSFNFVAMAIDSGNHS------ATVTVQ 1752
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V G P F+ + F V G S+GQ++ ND E V +L+ + G
Sbjct: 1753 VF--VTGEDEYDPVFLSQDFSFEVPEGAKKGQSIGQVQAND--EDGGVDGIVLYSFPTGS 1808
Query: 619 P-FAVEERSGVITVVDDLS 636
P F V + +GVI + D S
Sbjct: 1809 PYFDVNKTTGVIYLKLDSS 1827
Score = 56.4 bits (130), Expect = 6e-06
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 4/158 (2%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + Q+ LDRE + + + + A +G + A V + ++D NDN P F
Sbjct: 1612 GALRLQRALDREHQSTHTVIIQATDGQGHFALA---PVVVEVKDVNDNHPFFPVEVLTAS 1668
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I EN + + + + I G FM G GKE F VD N+G ++ D
Sbjct: 1669 IRENQPANSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSGEIR-SKIPFDF 1727
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
EK + +A D+G S+ + + + E++ P F
Sbjct: 1728 EKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYDPVF 1765
Score = 55.6 bits (128), Expect = 1e-05
Identities = 39/108 (36%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y EE V G + T + A Y + D D F + P TG LS + LD
Sbjct: 1150 YGGVTEEGFVINPVTGVITTTK-ELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGLD 1208
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
RET+ +Y L VVA D G DVNDNSP F A D L
Sbjct: 1209 RETKAEYTLEVVASDRG-SPALSTTVMVQVQVMDVNDNSPIFNADDAL 1255
Score = 55.6 bits (128), Expect = 1e-05
Identities = 60/236 (25%), Positives = 103/236 (43%), Gaps = 22/236 (9%)
Query: 145 RAFDRDKPNTPNSDVHYSIVSGND-DGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMA 203
RA DR+ +T H I+ D GHFAL PV++ +V D + F + ++
Sbjct: 1618 RALDREHQST-----HTVIIQATDGQGHFALA----PVVV--EVKDVNDNHPFFPVEVLT 1666
Query: 204 SGKRIHKEILFPEPI-HAIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELD 260
+ R ++ + HAID D GV L+Y ++ +G ++ FS+D +G + ++
Sbjct: 1667 ASIRENQPANSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSGEI--RSKIP 1724
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
D E + N+F A N T +V + D D P F ++ + E
Sbjct: 1725 FDFE---KINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYD--PVFLSQDFSFEVPEGAK 1779
Query: 321 NGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
G S+ QV A D+D G +G Y F ++ +G + ++ + + SS
Sbjct: 1780 KGQSIGQVQANDEDGGVDGIVLYSFPTGSPYFDVNKTTGVIYLKLDSSSSSSSSSS 1835
Score = 54.8 bits (126), Expect = 2e-05
Identities = 73/304 (24%), Positives = 118/304 (38%), Gaps = 28/304 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS----L 128
G+ Q+S ++V + DVND P+F + V E G +
Sbjct: 1089 GIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGHV 1148
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
T G I K + HY++ +G+ DG F L S L + L
Sbjct: 1149 TYGGVTEEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDGDFHLHPS-TGALSTSRGL 1207
Query: 189 DYDAGDKEFQLVIMASGK---------RIHKEILFPE---PIHAIDQDLGVGATLRYELI 236
D + E+ L ++AS + + +++ PI D L G L + +
Sbjct: 1208 DRET-KAEYTLEVVASDRGSPALSTTVMVQVQVMDVNDNSPIFNADDALN-GKFLYF--L 1263
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
S + F++D G + LD + F + + ++ N A+V + +
Sbjct: 1264 SQDAHGAFTVDENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRN----TSAQVTVTV 1319
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM-ATDKDQGENGEFTYQLDDPKGAFSID 355
LD+NDN P F D I + ++ + VL M A DKD G NG Y+ P FSI+
Sbjct: 1320 LDVNDNAPVFIQDPLVIEV--SIRHSQRVLATMKAEDKDFGANGSVFYRFATPVKGFSIN 1377
Query: 356 PRSG 359
+G
Sbjct: 1378 SLTG 1381
Score = 54.0 bits (124), Expect = 3e-05
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P + + L+A+D D+G+ G ++Y S D N
Sbjct: 1669 IRENQPANSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDP---------NSGEI 1719
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ + F A+D GN + ++V+VFV +++ PVF ++F V E
Sbjct: 1720 RSKIPFDFEKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYDPVFLSQDFSFEVPEGAK 1779
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
+ +G+V A D D G + + Y P+ + F+++ TGV+
Sbjct: 1780 KGQSIGQVQANDEDGGVDGIVLYSF-PTGSPY-FDVNKTTGVI 1820
Score = 53.6 bits (123), Expect = 4e-05
Identities = 68/301 (22%), Positives = 115/301 (38%), Gaps = 15/301 (4%)
Query: 620 FAVEERSGVITVVDDLSR-YNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F +++ SG + L R +D A + LS V V VVD+ND R
Sbjct: 51 FTIDKGSGQLCTSTPLDRDEGADKFDLTVTAT-DGGGLSSVARVRVSVVDINDNR----- 104
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
A P+++ V ++ + + + G V + + G I
Sbjct: 105 PAFYPVLYTVSLSTHSSPGTSVVKVTANDPDSGLNGRVTYRTVPGGGSAFFTLNKDTGVI 164
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+ L + V M + AE G+ + +V + + + PVFE A Y + E
Sbjct: 165 SLSRSLHGKANTVISMEIAAEDGGGLTAPVNA-RVNVSVVGGSVTSPVFEQAQYFFTVPE 223
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ GT + +++A+ G+ + G+ F VD +TG ++ LD E
Sbjct: 224 DVLRGTSL---GVVRASAKTGGSKDILYSISSGDPYGYFTVDSSTGTIR-TALPLDHETC 279
Query: 859 IMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
+L + AR + I I D NDN P F + +S+ + E GT +T
Sbjct: 280 SSLELEIQARYGFPPAYGTTRVRITISDINDNAPAF--LPSSSESLLLPEITKMGTVIYT 337
Query: 918 I 918
I
Sbjct: 338 I 338
Score = 53.6 bits (123), Expect = 4e-05
Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 13/138 (9%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G+L L++ LD EH +T ++Q Q + L A V +E+ D+NDN P F V+
Sbjct: 1611 SGALRLQRALD--REHQ-STHTVIIQATDGQGHFAL----APVVVEVKDVNDNHPFFPVE 1663
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG----AFSIDPRSGWLTVRN 365
SI EN P +V + A D D G G Y + + G +FS+DP SG +R+
Sbjct: 1664 VLTASIRENQPANSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSG--EIRS 1721
Query: 366 QTVLDREAHSSLRMKVYA 383
+ D E +S A
Sbjct: 1722 KIPFDFEKINSFNFVAMA 1739
Score = 50.8 bits (116), Expect = 3e-04
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
G + Y + SG+ F++DS G++ L LD E ++ L++QA + P
Sbjct: 241 GGSKDILYSISSGDPYGYFTVDSSTGTI--RTALPLDHE---TCSSLELEIQA-RYGFPP 294
Query: 286 KTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
RV I + D+NDN P F ++ + E G + + ATD+D G NG+ ++
Sbjct: 295 AYGTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFD 354
Query: 345 LDDPKGA-------FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTF 394
L A F +D SG VR L E+ ++V AK+ P + TF
Sbjct: 355 LVSAGAAGSSGQRTFGVDRGSG--EVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTF 410
Score = 50.4 bits (115), Expect = 4e-04
Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 10/141 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALD---GGNLNDNISVRVFVKDVNDHFPVFK 1046
F ++E G + + +L E + + + A+D N + V V V DVND+ PVF
Sbjct: 1271 FTVDENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVFI 1330
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVN 1105
+ V ++++RVL + A D DFG N ++ Y F P F I+ LTG +
Sbjct: 1331 QDPLVIEVS-IRHSQRVLATMKAEDKDFGANGSVFYRFATPVK---GFSINSLTGEIQAT 1386
Query: 1106 GELDRETEDKYILTVVARDNG 1126
L T+ + L V A D G
Sbjct: 1387 EPLQDLTQAQRTLIVEAMDQG 1407
Score = 49.2 bits (112), Expect = 9e-04
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 14/173 (8%)
Query: 218 IHAIDQDLGVGATLRYELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I A D+D G L ++L+S + ++ F +D +G + L L ++
Sbjct: 338 IQATDRDSGHNGQLSFDLVSAGAAGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVV 397
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
A QL++ T V I+ D P F+ Y + + EN P LQV A +
Sbjct: 398 AKDGGAPQLSS---TFTLVVHIQAQDARG--PNFDTLTYRVELRENTPLNTQFLQVRALN 452
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ +Y L D F I SGW+ VR+ LDRE + V A
Sbjct: 453 TEASGGSSISYHLRPDGDAAGFGIMSDSGWIFVRSS--LDREVKDMYLLTVLA 503
Score = 49.2 bits (112), Expect = 9e-04
Identities = 71/310 (22%), Positives = 125/310 (40%), Gaps = 21/310 (6%)
Query: 578 YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE---ERSGVITVVDD 634
+ F+ ++ IGT + + ND +SY L F + + SG + +
Sbjct: 1560 FVFFFPLDMLIGTEITLVTGNDVDSSPALSYSLQLDPTALGMFGIHRYNQWSGALRLQRA 1619
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL-LKGAHSPIIFHVKENSA 693
L R ++ + A + ++ V V DVND ++ + I + NSA
Sbjct: 1620 LDREHQSTHTVIIQATDGQGHFALAP-VVVEVKDVNDNHPFFPVEVLTASIRENQPANSA 1678
Query: 694 GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVY 752
+ I H + ++G+ F++ + ++ G I ++ P D EK + +
Sbjct: 1679 VTVLHAIDHD--TGVFGHLK---YFMLERTGTGKESFSVDPNSGEIRSKIPFDFEKINSF 1733
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
+A + G S QV + EDE D PVF + + E +K G I +
Sbjct: 1734 NFVAMA-IDSGNHSATVTVQVFVTGEDEYD--PVFLSQDFSFEVPEGAKKGQSIGQ---V 1787
Query: 813 KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
+A D D G + + +Y+ F G FDV++ TGV+ LD S + +G
Sbjct: 1788 QANDEDGGVDGIVLYS-FPTGSPYFDVNKTTGVIYL---KLDSSSSSSSSSSSSSSGSGR 1843
Query: 873 LSSEAELIIM 882
EA L+ +
Sbjct: 1844 TKREARLMTL 1853
Score = 46.8 bits (106), Expect = 0.005
Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 7/94 (7%)
Query: 1063 VLGKVDATDADFGQNANLTYFI-QPSDTDLP--FEISPLTGVLSVNGELDR-ETEDKYIL 1118
+L +V ATD D G +TY + PS P F I +G L + LDR E DK+ L
Sbjct: 18 MLAQVSATDEDRGSFGAVTYALGSPSGNTPPDQFTIDKGSGQLCTSTPLDRDEGADKFDL 77
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
TV A D G D+NDN P FY
Sbjct: 78 TVTATDGGGLSSVARVRVSVV---DINDNRPAFY 108
Score = 45.6 bits (103), Expect = 0.011
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGDSLDREKKI 859
T + M + ATD D G+ Y L + F +D+ +G + LDR++
Sbjct: 14 TRVSMLAQVSATDEDRGSFGAVTYALGSPSGNTPPDQFTIDKGSGQL-CTSTPLDRDEGA 72
Query: 860 -MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+ L++ A D GGLSS A + + + D NDN+P F
Sbjct: 73 DKFDLTVTATDGGGLSSVARVRVSVVDINDNRPAF 107
Score = 44.8 bits (101), Expect = 0.018
Identities = 52/194 (26%), Positives = 83/194 (42%), Gaps = 15/194 (7%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F P ++ IGT I + D+DS + + Y + P+ L + RY N+
Sbjct: 1561 VFFFPLDMLIGTEITLVTGNDVDS--SPALSYSLQ----LDPTALGM--FGIHRY---NQ 1609
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + R+L E S + I A DG V V VKDVND+ P F ++
Sbjct: 1610 WSGALRLQRALDREHQSTHTVIIQATDGQGHFALAPVVVEVKDVNDNHPFFPVEVLTASI 1669
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYF-IQPSDTDL-PFEISPLTGVLSVNGELDRET 1112
E Q + + A D D G +L YF ++ + T F + P +G + D E
Sbjct: 1670 RENQPANSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSGEIRSKIPFDFEK 1729
Query: 1113 EDKYILTVVARDNG 1126
+ + +A D+G
Sbjct: 1730 INSFNFVAMAIDSG 1743
Score = 44.0 bits (99), Expect = 0.032
Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
++ G + ++ LD E + L V+A +++ T+ + + L D+NDNLP F
Sbjct: 1443 NAAKGEIMVQSSKGLDFEDTPRLR---LVVKAESVSS---TSFMAINLILQDVNDNLPRF 1496
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
++ Y + E ++QV+A D DQG+NG+
Sbjct: 1497 QLQNYIAYMREAQGYDMPIIQVVAEDVDQGQNGQ 1530
Score = 42.3 bits (95), Expect = 0.099
Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 12/139 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V+V + ++ +PVF+ + + F + AK G IG+V+A D D G +G+VLY
Sbjct: 1749 VTVQVFVTGEDEYDPVFLSQD-FSFEVPEGAKKGQSIGQVQANDEDGGVDGIVLYSFPTG 1807
Query: 503 S-----NLTITSPFKINPNTGTVSVAESPILEG-----RHALFVEASDQPANPSER-RYS 551
S N T + ++ + S + S G R A + + +P + R +
Sbjct: 1808 SPYFDVNKTTGVIYLKLDSSSSSSSSSSSSSSGSGRTKREARLMTLDVKAQSPLDASRTT 1867
Query: 552 LAVVTIEVTRGTKGNKPDI 570
A VTI+VT G PD+
Sbjct: 1868 TAQVTIDVTNTNFGLAPDV 1886
>UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 814
Score = 155 bits (376), Expect = 9e-36
Identities = 197/791 (24%), Positives = 325/791 (41%), Gaps = 84/791 (10%)
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
R DA V+Y ++ E F ++ +GV+ + + MY F A +
Sbjct: 28 RDQDAALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSP 87
Query: 656 L-SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+ S + V + D ND R + P+ + + S +G I + ++ + T
Sbjct: 88 IRSAIATIHVQITDTNDNRPIF-----QPMEYETRV-SENTPLGTIV-ARVKAVDKDSTS 140
Query: 715 NVRFLIANQQDVTDDIAIAEDGT--IFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIY 771
N + + Q + ++ T I T+K D EK + Y +T+ +++ +S
Sbjct: 141 NADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFA 200
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF- 830
V I + DENDNPP F Y + EN +GT + + A D D G NA+ Y++
Sbjct: 201 NVVIIVVDENDNPPEFAQKRYTATVYENFTVGTVVLR---VTAHDKDSGPNAMLKYSIHS 257
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELII--MIGDE 886
G + F + ++G + + LD+E Y L L+ D G L S +++ ++
Sbjct: 258 GNTDDAFVIIADSGDIS-LDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGV 316
Query: 887 NDNKPEF-NQ-----IEEN-----SKVRIHR-ETKLNGTAGFTIIEVKPKNKFALDVDQL 934
N++ P F N+ I EN S VR+ E ++ A F + + V+Q
Sbjct: 317 NEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLVNQT 376
Query: 935 GPL---------------FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
G + F + EN+ GT ++ L A D D G+NGQ+ Y YI S
Sbjct: 377 GDITLARELDYETRRRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFY------YIVTS 430
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN--ISALDGGNLNDNIS--VRVFV 1035
VK F N G V + L ES ++ N + A DGG+ S V+V V
Sbjct: 431 -------SVKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEV 483
Query: 1036 KDVNDHFPVFKKTWYNFNVEEA-QYTRRVL--GKVDATDADFGQNANLTYFIQPSDTDLP 1092
D ND+ PVF +Y + EA R+L D D D G NA + YF++ +
Sbjct: 484 LDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKK 543
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F I+ TG +++ +D E Y V A D G DVNDN P F
Sbjct: 544 FSINDTTGQITIKQAVDYEERSSYSFEVFASDGG-EARLTGSSSVRITIIDVNDNRPYFL 602
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK-VFANDTDFIGNGN 1211
++ A + + + + G + K V +T +
Sbjct: 603 PTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGVVTTNK 662
Query: 1212 GLILYSLPQRK---NQQNLGLPSLSST--AILMVTVADVPDEVEMSDKPVFISRYYELEI 1266
L + + + G P L+S+ +L V+V ++ D + PVF + Y I
Sbjct: 663 SLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNIND-----NSPVFSQKMYSASI 717
Query: 1267 EEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
+EN V + V+ + + N K+ + IL E ++D + FV+D G + +S D E
Sbjct: 718 DENTTVGHVILRVTASDLDSSLNGKVLFSIL-EGNSDGK--FVVDQNTGVVTTNKSLDYE 774
Query: 1325 VKDTYEVIVRA 1335
Y ++++A
Sbjct: 775 DVTEYTLVIQA 785
Score = 150 bits (363), Expect = 3e-34
Identities = 178/707 (25%), Positives = 290/707 (41%), Gaps = 57/707 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D A L Y + +GN+ F++D+ G + KE D + + + L +
Sbjct: 131 VKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFDFE-----KTERYNLTIS 185
Query: 278 ASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
S P ++ A V I ++D NDN PEF Y ++ EN G VL+V A DKD
Sbjct: 186 VSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTVVLRVTAHDKDS 245
Query: 336 GENGEFTYQL-----DDP------KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
G N Y + DD G S+D T+ N T++ + K
Sbjct: 246 GPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIK 305
Query: 385 E--TNPSVVGTFADSQR-IAKWRRQPLETNAPLEKTTY---VFPDKVGTKTENIEYYDEQ 438
N V G + R + ++ + N PL + D V I +
Sbjct: 306 RMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDA 365
Query: 439 LMSFVNVEVTLLDANDNNPV-FVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
S V + D + + YEF M N GT + + A D D G NG V Y
Sbjct: 366 ASSKVFLVNQTGDITLARELDYETRRRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFY 425
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVV 555
+ +S + F N TG VS+ E ++ + V A D + P R + A V
Sbjct: 426 YIVTSS---VKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPP---RTASAHV 479
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLHGY 614
+EV + P P F Y + IGT + ++ ND ++++ V+ ++ +
Sbjct: 480 KVEVL--DCNDNP--PVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFL 535
Query: 615 EEGV---PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVN 670
++ + F++ + +G IT+ + R Y FE A A L+ ++ + ++DVN
Sbjct: 536 KDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVN 595
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D R L + + V+ + G + Q+ +++ S + G V F I +
Sbjct: 596 DNRPYFLPTRY--YVQLVENVAIGTPVTQVTASDLDS---SLNGKVLFSILGGNSDGKFV 650
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G + T K LD E Y + + A + ++ + + + + + NDN PVF
Sbjct: 651 IDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ 710
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKF 848
Y I EN+ +G I + A+D D N ++++ G F VD+NTGVV
Sbjct: 711 KMYSASIDENTTVGHVILR---VTASDLDSSLNGKVLFSILEGNSDGKFVVDQNTGVVT- 766
Query: 849 IGDSLDREKKIMYKLSLVARDTG----GLSSEAELIIMIGDENDNKP 891
SLD E Y L + A D G S L + + + NDN P
Sbjct: 767 TNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSP 813
Score = 118 bits (283), Expect = 2e-24
Identities = 151/601 (25%), Positives = 255/601 (42%), Gaps = 56/601 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A L+Y + SGN F + + +G + L+K LD + N T VL V
Sbjct: 238 VTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENY---TLVLIVT 294
Query: 278 ASQLNNPLKTAQARV-EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ PL++ + V + + +N++ P F +FYN SI ENLP G S+++V A + D
Sbjct: 295 DMGIP-PLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVS 353
Query: 337 ENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
F Y + D + F ++ ++G +T+ + LD E ++Y T+ + V T
Sbjct: 354 VGARFIYVIKDAASSKVFLVN-QTGDITLARE--LDYETRRRYEFEMYENVTSGTQVLTL 410
Query: 395 ADSQRIAKWRRQP---LETNA-----PLEKTTYVFPDKVGTKTENIEYYDEQLMS----- 441
R Q + T++ TT V E++ Y+ +++
Sbjct: 411 FAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGS 470
Query: 442 -----FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKA---VDPDLGQNG 493
+V+V +LD NDN PVF + Y + +GT I +V A D D G N
Sbjct: 471 PPRTASAHVKVEVLDCNDNPPVFT-TLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNA 529
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYS 551
+ Y L+ + ++ F IN TG +++ ++ E R ++ V ASD S
Sbjct: 530 EIRYFLK---DAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSS 586
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYD 609
+ + I+V N+ P F+ Y + NV IGT V Q+ + D+ V +
Sbjct: 587 VRITIIDV----NDNR---PYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFS 639
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL---QENANLSIVTNATVHV 666
+L G +G F +++ +GV+T L + Y A N S V V
Sbjct: 640 ILGGNSDG-KFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSV 698
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
V++ND V + +S + EN+ + I S + + G V F I
Sbjct: 699 VNINDNSPVFSQKMYSA---SIDENTTVGHV--ILRVTASDLDSSLNGKVLFSILEGNSD 753
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPP 785
+ G + T K LD E Y + + A + ++ + + + + + NDN P
Sbjct: 754 GKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSP 813
Query: 786 V 786
V
Sbjct: 814 V 814
Score = 91.5 bits (217), Expect = 2e-16
Identities = 136/589 (23%), Positives = 240/589 (40%), Gaps = 68/589 (11%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPE+ +G T++ + A D D+ LN ++ Y S S ++ YFVI+
Sbjct: 11 IIPEDFTVGGTLLTVLARDQDAALNARVTYSIVS--------FSTES----DYFVIDNIT 58
Query: 999 GHVIVARSLPPESE--FRLNISALDGGN-LNDNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
G V ++ E++ + ++ A D G+ + I+ + V + D ND+ P+F+ Y V
Sbjct: 59 GVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRV 118
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E ++ +V A D D NA+L Y IQ + + F I TG + E D E +
Sbjct: 119 SENTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFDFEKTE 178
Query: 1115 KYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+Y LT+ D G D NDN P+F K A N
Sbjct: 179 RYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEF-------AQKRYTATVYENFTV 231
Query: 1174 ESVMM-IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ-------- 1224
+V++ + + NA + ++ +D I +G I P K
Sbjct: 232 GTVVLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVL 291
Query: 1225 --QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
++G+P L S ++V V + V P F++ +Y I EN+ +V +
Sbjct: 292 IVTDMGIPPLESIKRMVVNV--IVSGVN-EHAPRFLNEFYNASIPENLPLGTSIVRVRAV 348
Query: 1283 EHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
E + R+ Y++ D + F+++ + G + L R D E + YE E
Sbjct: 349 EDDVSVGARFIYVI--KDAASSKVFLVN-QTGDITLARELDYETRRRYE-FEMYENVTSG 404
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDV-NDNSPKFTNGNRPLVTAIPTTAPFGYQ 1400
++ + ++ + G Y + V +K V NS T G L + + + Y
Sbjct: 405 TQVLTLFAHDRDEGINGQVFYYI-VTSSVKGVFTTNS---TTGVVSLTAELDRESVYQYN 460
Query: 1401 VMQLKGAIGHHP-TASRTVRADT-----DELVF---FERLSLNGLTS----------PQA 1441
++ + G P TAS V+ + + VF + L L+ TS
Sbjct: 461 MLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDR 520
Query: 1442 TDSDIGINADIRYQILNE-QAPRFAIDPVSGTVRVVAALARDAGRVFGF 1489
D D G+NA+IRY + + + +F+I+ +G + + A+ + + F
Sbjct: 521 DDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSF 569
Score = 90.6 bits (215), Expect = 3e-16
Identities = 104/377 (27%), Positives = 164/377 (43%), Gaps = 34/377 (9%)
Query: 578 YEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDL 635
YEF + NV GT V + +D E V Y ++ +GV F +GV+++ +L
Sbjct: 393 YEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGV-FTTNSTTGVVSLTAEL 451
Query: 636 SRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIFHVKENSA 693
R + Y+ VA Q+ + +A V V+D ND V ++ + S
Sbjct: 452 DRESVYQYNMLVVA-QDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEA--TSI 508
Query: 694 GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVY 752
G I ++ + +R+ + + V+ +I + G I ++ +D E+R Y
Sbjct: 509 GTRILRVSANDRDDKDEGVNAEIRYFLKDAI-VSKKFSINDTTGQITIKQAVDYEERSSY 567
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
V A + G G V I I D NDN P F Y ++EN IGT + +
Sbjct: 568 SFEVFAS-DGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQ---V 623
Query: 813 KATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
A+D D N ++++ G + F +D+NTGVV SLD E Y L + A D G
Sbjct: 624 TASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGVVT-TNKSLDYEDVTEYTLVIQATDCG 682
Query: 872 ----GLSSEAELIIMIGDENDNKPEFNQ------IEENSKV-----RIHR---ETKLNGT 913
S L + + + NDN P F+Q I+EN+ V R+ ++ LNG
Sbjct: 683 DPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGK 742
Query: 914 AGFTIIEVKPKNKFALD 930
F+I+E KF +D
Sbjct: 743 VLFSILEGNSDGKFVVD 759
Score = 86.2 bits (204), Expect = 6e-15
Identities = 75/252 (29%), Positives = 118/252 (46%), Gaps = 25/252 (9%)
Query: 907 ETKLNGTAG--FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
E +L G++ TII+V + L L EN+ IGT + ++ A DLDS LNG
Sbjct: 578 EARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLV---ENVAIGTPVTQVTASDLDSSLNG 634
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDG 1022
++ + S L ++ FVI++ G V +SL E +E+ L I A D
Sbjct: 635 KVLF----------SILGGNS---DGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDC 681
Query: 1023 GNLNDNIS----VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
G+ N S + V V ++ND+ PVF + Y+ +++E V+ +V A+D D N
Sbjct: 682 GDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNG 741
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXX 1137
+ + I ++D F + TGV++ N LD E +Y L + A D G
Sbjct: 742 KVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGML 801
Query: 1138 XXXXXDVNDNSP 1149
++NDNSP
Sbjct: 802 HVSVVNINDNSP 813
Score = 79.0 bits (186), Expect = 9e-13
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 8/165 (4%)
Query: 220 AIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A DQD + A + Y ++S + F +D++ G + KE D + + + V+A
Sbjct: 27 ARDQDAALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQR-----MYSFSVRA 81
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+P+++A A + +++ D NDN P F+ Y + EN P G V +V A DKD N
Sbjct: 82 EDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSN 141
Query: 339 GEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+ Y + + G+F+ID +G + R + ++ +L + V
Sbjct: 142 ADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFDFEKTERYNLTISV 186
Score = 68.1 bits (159), Expect = 2e-09
Identities = 87/374 (23%), Positives = 150/374 (40%), Gaps = 32/374 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ + V + D NDN P+F P YE + N +GT++ +VKAVD D N ++Y +Q
Sbjct: 91 AIATIHVQITDTNDNRPIFQPME-YETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ 149
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+N F I+ +TG + + E R+ L + SD P+ + A V I
Sbjct: 150 NGNN---NGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGV-PALSSLNFANVVII 205
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEG 617
V + + P P+F Y V N +GT V ++ +D N + +H
Sbjct: 206 VV--DENDNP--PEFAQKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSIHSGNTD 261
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVV--DVNDERG 674
F + SG I++ L + Y + L + V+V+ VN+
Sbjct: 262 DAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAP 321
Query: 675 VLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AI 732
L ++ + EN G +I + ++ + + RF+ + + + +
Sbjct: 322 RFLNEFYNA---SIPENLPLGTSI-----VRVRAVEDDVSVGARFIYVIKDAASSKVFLV 373
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH--- 789
+ G I + LD E R Y E + V SG + + + DE N VF +
Sbjct: 374 NQTGDITLARELDYETRRRYEF----EMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVT 429
Query: 790 ATYEGFIMENSKIG 803
++ +G NS G
Sbjct: 430 SSVKGVFTTNSTTG 443
Score = 66.9 bits (156), Expect = 4e-09
Identities = 94/378 (24%), Positives = 151/378 (39%), Gaps = 47/378 (12%)
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGV 1101
P+F +T Y+ + E L V A D D NA +TY I T+ F I +TGV
Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGV 60
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ + E D ET+ Y +V A D G D NDN P F + E +
Sbjct: 61 VRSSKEFDYETQRMYSFSVRAEDRG-SPIRSAIATIHVQITDTNDNRPIFQPME--YETR 117
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL------ 1215
E L V + NA + ++ N + I N G I+
Sbjct: 118 VSENTPLGT----IVARVKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFD 173
Query: 1216 YSLPQRKN----QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
+ +R N + G+P+LSS V + V E + P F + Y + EN
Sbjct: 174 FEKTERYNLTISVSDTGVPALSSLNFANVVIIVVD---ENDNPPEFAQKRYTATVYENFT 230
Query: 1272 APVELVSLNLTEHYE----NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
V V L +T H + N ++Y I + N D FVI +G + L + D+E +
Sbjct: 231 --VGTVVLRVTAHDKDSGPNAMLKYSIHSGNTDD---AFVIIADSGDISLDKPLDKETIE 285
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPL 1387
Y +++ ++ + LE + + V V+V VN+++P+F N
Sbjct: 286 NYTLVL-------------IVTDMGIPPLESIKRMVVNVIV--SGVNEHAPRFL--NEFY 328
Query: 1388 VTAIPTTAPFGYQVMQLK 1405
+IP P G +++++
Sbjct: 329 NASIPENLPLGTSIVRVR 346
Score = 55.2 bits (127), Expect = 1e-05
Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 8/122 (6%)
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDEN 842
P+F Y I E+ +G + + A D D NA Y++ F + F +D
Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLT---VLARDQDAALNARVTYSIVSFSTESDYFVIDNI 57
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENS 900
TGVV+ D E + MY S+ A D G S+ A + + I D NDN+P F +E +
Sbjct: 58 TGVVRS-SKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYET 116
Query: 901 KV 902
+V
Sbjct: 117 RV 118
Score = 46.8 bits (106), Expect = 0.005
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 29/127 (22%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
SA ++ V I D NDN PIF Y V E TP G
Sbjct: 90 SAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLG------------------------ 125
Query: 138 LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
TI ++A D+D +T N+D+ YSI +GN++G F +++S + + RK D++ ++ +
Sbjct: 126 -TIVARVKAVDKD--STSNADLIYSIQNGNNNGSFTIDNSTGEI-MTRKEFDFEKTER-Y 180
Query: 198 QLVIMAS 204
L I S
Sbjct: 181 NLTISVS 187
Score = 36.3 bits (80), Expect = 6.5
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 30/161 (18%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
Q+ G P +++A + V V D D + PVF + YY L++ E + ++ ++ +
Sbjct: 466 QDGGSPPRTASAHVKVEVLDCND-----NPPVFTTLYYTLQLSEATSIGTRILRVSANDR 520
Query: 1285 YE-----NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ N ++RY++ D + + F I+ G + + ++ D E ER
Sbjct: 521 DDKDEGVNAEIRYFL---KDAIVSKKFSINDTTGQITIKQAVDYE-----------ERSS 566
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
YS E+ A D E V + I DVNDN P F
Sbjct: 567 YSFEV------FASDGGEARLTGSSSVRITIIDVNDNRPYF 601
>UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep:
CHz-cadherin - Gallus gallus (Chicken)
Length = 2819
Score = 154 bits (373), Expect = 2e-35
Identities = 245/978 (25%), Positives = 398/978 (40%), Gaps = 138/978 (14%)
Query: 396 DSQR-IAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
DSQ+ I K RR P L+ Y+ + +N+ L SF V V + D N+
Sbjct: 663 DSQKGIIKLRRSPAPN---LKGPQYIL--NITAIDDNVSGGPTPLSSFAEVIVGVNDINN 717
Query: 455 NNPVFVPSNLYEFS--MKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
N PVF Y S + N GT + +V+A D DLG NG V Y L ++ F
Sbjct: 718 NKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRDGASLG--FS 775
Query: 513 INPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
I+ +TG ++ S E + H L V A+DQ P + V+ +V N D
Sbjct: 776 IDSDTGVITTTRSFDREEQKEHTLSVTATDQAPEPLIGICQITVLIADV------NDND- 828
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGV 628
P F + Y++++ + IGTS ++ +D+ + + ++Y +L + F + +G
Sbjct: 829 PKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSMLAHQVQY--FQINPSTGW 886
Query: 629 ITVVDDLSRYNRPMYDFEAVA---LQENANLSI-VTNA--------------TVHVVDVN 670
+ V +S+ R + A L++ +TNA TV +
Sbjct: 887 VYVNHRISQTTRISHYIVATDGGNRSSTVELTVTITNALSQPPRWEQSRYWVTVPENTIR 946
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D R V +K A SP+ + GQ+ TNM + +L N+ D + +
Sbjct: 947 DTRIVTIK-ATSPL--GDPRVTYNLEEGQVPETNMPIRF--------YLRPNRADGSASL 995
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+AE PLD E + +TV A+ N +I A V + + D NDN P F +
Sbjct: 996 LVAE--------PLDFETTKFFSLTVRAQ-NVAMIPLASFTIVYVNVTDVNDNVPFFVSS 1046
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE---MFDVDENTGVVK 847
YE + E + +GT + + ATD D G + Y + + E F ++ TG++
Sbjct: 1047 NYEVSVPEGADVGTSVVQ---VLATDLDSGLHGQVRYFILKDASEDYQFFTIEPETGIIS 1103
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
S DREK+ Y + + ++D SSE+ + G N + + VRI
Sbjct: 1104 THA-SFDREKRASYLIEVQSQD----SSESARPGVHGHPNT---------DTAYVRIFVS 1149
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
+ F P+ + + VD E+ +G+ ++ A D D G N ++R
Sbjct: 1150 DVNDNAPAF------PQPVYEVSVD---------EDRDVGSPVVTATADDRDEGANAKLR 1194
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNL 1025
Y+ S K F + G V + +SL E E + L + A DG
Sbjct: 1195 YQITSG-------------NTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKWE 1241
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNAN-LTYF 1083
N + + + V + ND PVF + Y+ ++ EE + KV ATD D + N L+Y
Sbjct: 1242 NHTLII-INVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYS 1300
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
+ F I+ TG +S N LDRE + V+A D D
Sbjct: 1301 LHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDE-SGEGLTGFADVVIEVRD 1359
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
NDN+P F + + D ++ + + + +A + + + N+
Sbjct: 1360 TNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNE 1419
Query: 1204 TDF----IGNGNGLI---LYSLPQRKNQQNLGL------PSLSSTAILMVTVADVPDEVE 1250
+ I +G I L SL + K + L + L+ T + V DV D
Sbjct: 1420 INLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTATILVTDVNDHA- 1478
Query: 1251 MSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVI 1308
PVF+ R Y + EN +N V +VS + EN + + IL + D D + +
Sbjct: 1479 ----PVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSIL-DGDNDCKFSIET 1533
Query: 1309 DPRN--GTLYLVRSPDRE 1324
D N G ++L + D E
Sbjct: 1534 DKGNNCGFIHLRKQIDFE 1551
Score = 118 bits (283), Expect = 2e-24
Identities = 120/468 (25%), Positives = 206/468 (44%), Gaps = 32/468 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L S V V + D ND +P F S ++ +GT + +V A D D G N +
Sbjct: 490 ESALSSVAEVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEI 549
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y +Q T + +IT I+ N + + E FV + +P R A V
Sbjct: 550 SYFIQST-DFSITRHGVISSNQRLNFERANHMYE-----FVVIAVDKGHPP--RTGTASV 601
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
I++ + P F Y ++ + G T V +R D + + V Y + G E
Sbjct: 602 RIQMANVND----EAPVFSQPVYRTFLSEDAGPSTLVATVRAKDP-DGDGVLYLIAGGNE 656
Query: 616 EGVPFAVEERSGVITVV-DDLSRYNRPMYDFEAVALQENAN-----LSIVTNATVHVVDV 669
EG F ++ + G+I + P Y A+ +N + LS V V D+
Sbjct: 657 EG-NFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDI 715
Query: 670 NDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
N+ + V + + V EN G + Q+ + + NG V++ + ++ +
Sbjct: 716 NNNKPVFRECTYYSDSTWVLENQPPGTYVLQV-EAYDADLGVNG--EVKYGLMHRDGASL 772
Query: 729 DIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+I D G I T + DRE++ + ++V A ++ GI Q+T+ I D NDN P F
Sbjct: 773 GFSIDSDTGVITTTRSFDREEQKEHTLSVTAT-DQAPEPLIGICQITVLIADVNDNDPKF 831
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
E++ Y+ F+ E++ IGT + A D+D+G NA Y++ + F ++ +TG V
Sbjct: 832 ENSRYQYFLSEDTPIGTSFLR---VTAHDSDQGVNAAITYSMLAHQVQYFQINPSTGWV- 887
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
++ + + +I + +VA D G SS EL + I + P + Q
Sbjct: 888 YVNHRISQTTRISH--YIVATDGGNRSSTVELTVTITNALSQPPRWEQ 933
Score = 91.5 bits (217), Expect = 2e-16
Identities = 123/470 (26%), Positives = 192/470 (40%), Gaps = 45/470 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL-YDLQRTSNL 505
+ +++ ND PVF + + ++ + + KV A DPD + L Y L
Sbjct: 1248 INVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQG-- 1305
Query: 506 TITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGT 563
S F IN NTG +S E R V A+D+ E A V IEV R T
Sbjct: 1306 -AGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESG---EGLTGFADVVIEV-RDT 1360
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND-----AFEQNDVSYDLLHGYEEGV 618
N P + +V + T+V ++ D A ++Y ++ + +
Sbjct: 1361 NDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEI 1420
Query: 619 P---FAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F++ SG I TV+ L R Y V ++ L+ AT+ V DVND
Sbjct: 1421 NLNLFSINPVSGTICTVLGSLDREKVDKY-LLVVEARDGGGLTGTGTATILVTDVNDHAP 1479
Query: 675 VLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V L+ ++ V EN S + + + M G ++ D I
Sbjct: 1480 VFLQRIYTAF---VSENASINTEVAVV--SAMDRDEGENAMVTFSILDGDNDCKFSIETD 1534
Query: 734 ED---GTIFTQKPLDREK--RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ G I +K +D EK V+ +T+ AE + I IY+ED ND+ PVF
Sbjct: 1535 KGNNCGFIHLRKQIDFEKPHERVFNLTLKAED----MDFFSIAHCVIYVEDANDHAPVFY 1590
Query: 789 HATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGV 845
YE + E+ +GT++ + A D D G N F + L + F V + V
Sbjct: 1591 PQFYEVASLAEDVPVGTKVVQ---VSAVDLDSGLNGRFSFHLLNKSDPGGQFSVASDGWV 1647
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ + LD E Y+L ++A D G L+ A +++ + D NDN PEF
Sbjct: 1648 I--VAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEF 1695
Score = 90.6 bits (215), Expect = 3e-16
Identities = 114/479 (23%), Positives = 198/479 (41%), Gaps = 43/479 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVF--VPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQ 491
E L F +V + + D NDN P+F V + + + ++ T + ++ AVD P
Sbjct: 1345 EGLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKAST 1404
Query: 492 NGMVLYDL-QRTSNLTITSPFKINPNTGTV-SVAESPILE--GRHALFVEASDQPANPSE 547
+ ++ Y + Q N + F INP +GT+ +V S E ++ L VEA D
Sbjct: 1405 HAVLTYRIIQNVQNEINLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGGLTGT 1464
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-- 605
++ V + P F+ Y +V N I T V + D E +
Sbjct: 1465 GTATILVTDVN---------DHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAM 1515
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSR---YNRPMYD-FEAVALQENANLSIVTN 661
V++ +L G + F++E G L + + +P F E+ + + +
Sbjct: 1516 VTFSILDG-DNDCKFSIETDKGNNCGFIHLRKQIDFEKPHERVFNLTLKAEDMDFFSIAH 1574
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLI 720
++V D ND V P + V + +G ++ + + G F +
Sbjct: 1575 CVIYVEDANDHAPVFY-----PQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHL 1629
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
N+ D ++A DG + LD E Y++ VIA + G A V + ++D
Sbjct: 1630 LNKSDPGGQFSVASDGWVIVAGVLDHETVTQYQLIVIAT-DMGQPPLACSATVLVTLQDV 1688
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMD---NIIKATDADEGTN-ALFMYTLFGEGKEM 836
NDN P FE A Y + EN+ ++M+ ++ A D D N A F + L +
Sbjct: 1689 NDNGPEFE-AHYNPVVWENTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSL 1747
Query: 837 --FDVDE--NTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
F + + N + + DRE ++ L ++ D+G +SS L + IGD+ND+
Sbjct: 1748 GNFHLQDFHNGSALLTALHTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDH 1806
Score = 78.2 bits (184), Expect = 2e-12
Identities = 86/342 (25%), Positives = 150/342 (43%), Gaps = 52/342 (15%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFL-------------DTPYHVTVDELT------PTGEKAF 117
++ + V + + D NDN P+FL D+P V E+T P
Sbjct: 1347 LTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHA 1406
Query: 118 IF---LIAPIGPSLTIPLTV--PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF 172
+ +I + + + L P TI + + DR+K D + +V D G
Sbjct: 1407 VLTYRIIQNVQNEINLNLFSINPVSGTICTVLGSLDREKV-----DKYLLVVEARDGG-- 1459
Query: 173 ALESSHKPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATL 231
L + +L+ V D+ + ++ I+ E+ + A+D+D G A +
Sbjct: 1460 GLTGTGTATILVTDVNDHAPVFLQRIYTAFVSENASINTEVAV---VSAMDRDEGENAMV 1516
Query: 232 RYELISGNDRKLFSLDSVNGS----LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
+ ++ G++ FS+++ G+ + L K++D + H F L ++A ++
Sbjct: 1517 TFSILDGDNDCKFSIETDKGNNCGFIHLRKQIDFEKPHE---RVFNLTLKAEDMDF-FSI 1572
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNI-SIVENLPNGFSVLQVMATDKDQGENGEFTYQL- 345
A + +E D ND+ P F FY + S+ E++P G V+QV A D D G NG F++ L
Sbjct: 1573 AHCVIYVE--DANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHLL 1630
Query: 346 --DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
DP G FS+ GW+ V VLD E + ++ V A +
Sbjct: 1631 NKSDPGGQFSV-ASDGWVIVAG--VLDHETVTQYQLIVIATD 1669
Score = 76.6 bits (180), Expect = 5e-12
Identities = 97/410 (23%), Positives = 163/410 (39%), Gaps = 31/410 (7%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L GT TI+ + + + ++ F + EN I T + ++A+D D G N + +
Sbjct: 1461 LTGTGTATILVTDVNDHAPVFLQRIYTAF-VSENASINTEVAVVSAMDRDEGENAMVTFS 1519
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI 1029
+ ++E + H + P E F L + A D +
Sbjct: 1520 I-----LDGDNDCKFSIETDKGNNCGFIHLRKQIDFEKPHERVFNLTLKAEDMDFFSIAH 1574
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFN--VEEAQYTRRVLGKVDATDADFGQNANLTY-FIQP 1086
V ++V+D NDH PVF +Y E+ +V+ +V A D D G N ++ +
Sbjct: 1575 CV-IYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVV-QVSAVDLDSGLNGRFSFHLLNK 1632
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
SD F ++ G + V G LD ET +Y L V+A D G DVND
Sbjct: 1633 SDPGGQFSVAS-DGWVIVAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQ-DVND 1690
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N P+F A + W++ + + N S ++ + T AP + F + +F
Sbjct: 1691 NGPEFEAHYNPVVWENTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNF 1750
Query: 1207 ----IGNGNGLI--LYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMS 1252
NG+ L+ L++ + ++ + G+P +SST L V + D D +
Sbjct: 1751 HLQDFHNGSALLTALHTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDHPHSA 1810
Query: 1253 DKPVFISRYYE----LEIEENVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
+ Y+ + V AP +E RY+ILN+N
Sbjct: 1811 GYMECLIYSYDGILPTTVLGQVLAPDGDDWDRKIYQFEGKTSRYFILNDN 1860
Score = 72.5 bits (170), Expect = 8e-11
Identities = 50/153 (32%), Positives = 73/153 (47%), Gaps = 11/153 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDA--EHNLQANTFVL 274
+ A D DLGV ++Y L+ + L FS+DS G + + D + EH L
Sbjct: 747 VEAYDADLGVNGEVKYGLMHRDGASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTA--- 803
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
Q PL ++ + + D+NDN P+FE Y + E+ P G S L+V A D D
Sbjct: 804 ---TDQAPEPL-IGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSD 859
Query: 335 QGENGEFTY-QLDDPKGAFSIDPRSGWLTVRNQ 366
QG N TY L F I+P +GW+ V ++
Sbjct: 860 QGVNAAITYSMLAHQVQYFQINPSTGWVYVNHR 892
Score = 68.1 bits (159), Expect = 2e-09
Identities = 56/182 (30%), Positives = 93/182 (51%), Gaps = 16/182 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D G A LRY++ SGN + +F ++ G++F+ + LD + E + ++
Sbjct: 1182 ADDRDEGANAKLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELR--LVASDGK 1239
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN-GFSVLQVMATDKDQ-GE 337
N+ L + I +++ ND P F + Y+ SI+E L + VL+V ATD DQ +
Sbjct: 1240 WENHTL------IIINVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEAD 1293
Query: 338 NGEFTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
+Y L +GA FSI+ +G ++ + LDRE S+ R V A + + + F
Sbjct: 1294 QNALSYSLHG-QGAGSEFSINENTGEISANRR--LDREKRSTWRFLVLATDESGEGLTGF 1350
Query: 395 AD 396
AD
Sbjct: 1351 AD 1352
Score = 67.3 bits (157), Expect = 3e-09
Identities = 51/164 (31%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L Y L++ N LF++ +G L L +D + EH+L + L ++A + + L + A
Sbjct: 444 LSYSLLT-NPSGLFTVRQESGELLLTHPVDYEGEHHL----YHLLLKAVEAESALSSV-A 497
Query: 291 RVEIELLDLNDNLPEFEVDFYNI-SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
V + + D ND PEF+ Y+ +I E +P G S+LQV+ATD D G N E +Y +
Sbjct: 498 EVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQSTD 557
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
FSI R G ++ + +R H + + + +P GT
Sbjct: 558 --FSI-TRHGVISSNQRLNFERANHMYEFVVIAVDKGHPPRTGT 598
Score = 66.9 bits (156), Expect = 4e-09
Identities = 73/258 (28%), Positives = 110/258 (42%), Gaps = 30/258 (11%)
Query: 912 GTAGFT--IIEVKPKNKFA---LDVDQLGPLFLIPENIPIGTTIIKLNALDLD---SGLN 963
G GF +IEV+ N A L V + +PE+ P T ++++ A+DLD + +
Sbjct: 1346 GLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTH 1405
Query: 964 GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI-VARSLPPES--EFRLNISAL 1020
+ Y V ++++ + F IN G + V SL E ++ L + A
Sbjct: 1406 AVLTYRIIQNVQ---NEINLNL------FSINPVSGTICTVLGSLDREKVDKYLLVVEAR 1456
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
DGG L + + V DVNDH PVF + Y V E + V A D D G+NA +
Sbjct: 1457 DGGGLTGTGTATILVTDVNDHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMV 1516
Query: 1081 TYFIQPSDTDLPFEISP----LTGVLSVNGELDRET--EDKYILTVVARDNGXXXXXXXX 1134
T+ I D D F I G + + ++D E E + LT+ A D
Sbjct: 1517 TFSILDGDNDCKFSIETDKGNNCGFIHLRKQIDFEKPHERVFNLTLKAED----MDFFSI 1572
Query: 1135 XXXXXXXXDVNDNSPKFY 1152
D ND++P FY
Sbjct: 1573 AHCVIYVEDANDHAPVFY 1590
Score = 66.1 bits (154), Expect = 7e-09
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 14/173 (8%)
Query: 992 FVINERHGHVIVARSLPPE---SEFRLNISALD----GGN--LNDNISVRVFVKDVNDHF 1042
F ++ + G + + RS P ++ LNI+A+D GG L+ V V V D+N++
Sbjct: 660 FELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNK 719
Query: 1043 PVFKK-TWYNFN--VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-TDLPFEISPL 1098
PVF++ T+Y+ + V E Q + +V+A DAD G N + Y + D L F I
Sbjct: 720 PVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRDGASLGFSIDSD 779
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TGV++ DRE + ++ L+V A D DVNDN PKF
Sbjct: 780 TGVITTTRSFDREEQKEHTLSVTATDQ-APEPLIGICQITVLIADVNDNDPKF 831
Score = 64.5 bits (150), Expect = 2e-08
Identities = 58/172 (33%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN----- 282
G + Y + GN+ F LDS G + L + NL+ ++L + A N
Sbjct: 644 GDGVLYLIAGGNEEGNFELDSQKGIIKLRRS----PAPNLKGPQYILNITAIDDNVSGGP 699
Query: 283 NPLKTAQARVEIELLDLNDNLPEF-EVDFYNIS--IVENLPNGFSVLQVMATDKDQGENG 339
PL + A V + + D+N+N P F E +Y+ S ++EN P G VLQV A D D G NG
Sbjct: 700 TPLSSF-AEVIVGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNG 758
Query: 340 EFTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
E Y L GA FSID +G +T DRE + V A + P
Sbjct: 759 EVKYGLMHRDGASLGFSIDSDTGVITTTRS--FDREEQKEHTLSVTATDQAP 808
Score = 61.7 bits (143), Expect = 2e-07
Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 7/167 (4%)
Query: 220 AIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQ 275
A D D G+ +RY ++ + D + F+++ G + D + A + ++ +
Sbjct: 1067 ATDLDSGLHGQVRYFILKDASEDYQFFTIEPETGIISTHASFDREKRASYLIEVQSQDSS 1126
Query: 276 VQASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A ++ T A V I + D+NDN P F Y +S+ E+ G V+ A D+D
Sbjct: 1127 ESARPGVHGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRD 1186
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
+G N + YQ+ + KG F ++P +G + + + E LR+
Sbjct: 1187 EGANAKLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRL 1233
Score = 56.4 bits (130), Expect = 6e-06
Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 19/159 (11%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
QN+ + L+S I+ V V DV D V P F+S YE+ + E + +V + T+
Sbjct: 1016 QNVAMIPLASFTIVYVNVTDVNDNV-----PFFVSSNYEVSVPEGADVGTSVVQVLATDL 1070
Query: 1285 YENF--KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
++RY+IL + D + F I+P G + S DRE + +Y + V+++ S
Sbjct: 1071 DSGLHGQVRYFILKDASEDYQ-FFTIEPETGIISTHASFDREKRASYLIEVQSQDSSES- 1128
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVV-VRIKDVNDNSPKF 1380
A + G D V + + DVNDN+P F
Sbjct: 1129 ---------ARPGVHGHPNTDTAYVRIFVSDVNDNAPAF 1158
Score = 56.4 bits (130), Expect = 6e-06
Identities = 32/102 (31%), Positives = 55/102 (53%), Gaps = 6/102 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY----QLDD 347
V + + D+NDN+P F Y +S+ E G SV+QV+ATD D G +G+ Y +
Sbjct: 1029 VYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFILKDASE 1088
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
F+I+P +G + DRE +S ++V +++++ S
Sbjct: 1089 DYQFFTIEPETG--IISTHASFDREKRASYLIEVQSQDSSES 1128
Score = 54.4 bits (125), Expect = 2e-05
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 24/218 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE IPIGT+++++ A D DSG N +I Y S + + R+ VI+
Sbjct: 523 IPETIPIGTSLLQVLATDCDSGSNSEISYFIQSTDF-----------SITRHGVISSNQ- 570
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ R+ + + A+D G+ SVR+ + +VND PVF + Y + E
Sbjct: 571 RLNFERA---NHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSED 627
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV-NGELDRETEDKY 1116
++ V A D D + Y I + + FE+ G++ + +Y
Sbjct: 628 AGPSTLVATVRAKDPD---GDGVLYLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQY 684
Query: 1117 ILTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
IL + A D +G D+N+N P F
Sbjct: 685 ILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVF 722
Score = 53.2 bits (122), Expect = 5e-05
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 12/166 (7%)
Query: 992 FVINERHGHVIVARSLPPESE---FRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKK 1047
F + + G +++ + E E + L + A++ + +++ V V + D ND P F+
Sbjct: 456 FTVRQESGELLLTHPVDYEGEHHLYHLLLKAVEAESALSSVAEVMVHITDENDCSPEFQN 515
Query: 1048 TWYNF-NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ Y+ N+ E L +V ATD D G N+ ++YFIQ +D F I+ GV+S N
Sbjct: 516 SIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQSTD----FSIT-RHGVISSNQ 570
Query: 1107 ELDRE-TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L+ E Y V+A D G +VND +P F
Sbjct: 571 RLNFERANHMYEFVVIAVDKG-HPPRTGTASVRIQMANVNDEAPVF 615
Score = 47.6 bits (108), Expect = 0.003
Identities = 32/110 (29%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKM 1290
+ TA + + V+DV D +PV YE+ ++E+ V +PV + + + N K+
Sbjct: 1139 TDTAYVRIFVSDVNDNAPAFPQPV-----YEVSVDEDRDVGSPVVTATADDRDEGANAKL 1193
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
RY I + N + F ++P GT+++V+S D E + YE+ + A K+
Sbjct: 1194 RYQITSGNTKGV---FDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKW 1240
Score = 44.8 bits (101), Expect = 0.018
Identities = 86/343 (25%), Positives = 140/343 (40%), Gaps = 71/343 (20%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
+ T+ + DVND+ P+FL Y AF+ A I + +
Sbjct: 1466 TATILVTDVNDHAPVFLQRIY------------TAFVSENASINTEVAV----------- 1502
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALES---SHKPVLLLRKVLDYD------- 191
+ A DRD+ N+ V +SI+ G++D F++E+ ++ + LRK +D++
Sbjct: 1503 --VSAMDRDEGE--NAMVTFSILDGDNDCKFSIETDKGNNCGFIHLRKQIDFEKPHERVF 1558
Query: 192 -----AGDKEF----QLVIMASGKRIHKEILFPE--PIHAIDQDLGVGATL----RYELI 236
A D +F VI H + +P+ + ++ +D+ VG + +L
Sbjct: 1559 NLTLKAEDMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLD 1618
Query: 237 SG-NDRKLFSL---DSVNGSLFLEKELDLDAEHNLQANT---FVLQVQASQLNNPLKTAQ 289
SG N R F L G + + + L T + L V A+ + P
Sbjct: 1619 SGLNGRFSFHLLNKSDPGGQFSVASDGWVIVAGVLDHETVTQYQLIVIATDMGQPPLACS 1678
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ------VMATDKDQGENG-EFT 342
A V + L D+NDN PEFE YN + EN + SV + A D+D NG F+
Sbjct: 1679 ATVLVTLQDVNDNGPEFEA-HYNPVVWENTASPQSVQMNETSTLLYAKDRDTAANGAPFS 1737
Query: 343 YQL---DDPKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKV 381
+ L D G F + D +G + DRE H + +
Sbjct: 1738 FHLLSNFDSLGNFHLQDFHNGSALLTALHTFDREVHKVFHLPI 1780
Score = 43.2 bits (97), Expect = 0.056
Identities = 73/285 (25%), Positives = 117/285 (41%), Gaps = 27/285 (9%)
Query: 90 VNDNVPIFLDTPYHVTVDELTPTGEKAFI-----FLIAPIGPSLTIPLTVPRGL-TIFKD 143
V P F + Y V V E TP GEK + F P+ SL LT P GL T+ ++
Sbjct: 405 VGSRPPQFTNMSYSVFVPENTPPGEKVAVVEAVSFQSQPLSYSL---LTNPSGLFTVRQE 461
Query: 144 IRAFDRDKPNTPNSDVH-YSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIM 202
P + H Y ++ + AL S + ++ + D + EFQ I
Sbjct: 462 SGELLLTHPVDYEGEHHLYHLLLKAVEAESALSSVAEVMV---HITDENDCSPEFQNSIY 518
Query: 203 ASGKRIHKEILFPEP---IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKEL 259
S I + I + A D D G + + Y I D FS+ +G + + L
Sbjct: 519 -SRDNIPETIPIGTSLLQVLATDCDSGSNSEISY-FIQSTD---FSITR-HGVISSNQRL 572
Query: 260 DLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL 319
+ + +++ FV V A +P +T A V I++ ++ND P F Y + E+
Sbjct: 573 NFERANHMYE--FV--VIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSEDA 628
Query: 320 PNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVR 364
V V A D D G+ + + +G F +D + G + +R
Sbjct: 629 GPSTLVATVRAKDPD-GDGVLYLIAGGNEEGNFELDSQKGIIKLR 672
Score = 43.2 bits (97), Expect = 0.056
Identities = 24/69 (34%), Positives = 34/69 (49%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D S + + + DAND+ PVF P S+ + VGT + +V AVD D G NG
Sbjct: 1566 DMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRF 1625
Query: 496 LYDLQRTSN 504
+ L S+
Sbjct: 1626 SFHLLNKSD 1634
Score = 41.1 bits (92), Expect = 0.23
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 9/112 (8%)
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
PP F + +Y F+ EN+ G ++ + +A + Y+L +F V + +
Sbjct: 409 PPQFTNMSYSVFVPENTPPGEKVAV------VEAVSFQSQPLSYSLLTNPSGLFTVRQES 462
Query: 844 GVVKFIGDSLDRE-KKIMYKLSLVARDT-GGLSSEAELIIMIGDENDNKPEF 893
G + + +D E + +Y L L A + LSS AE+++ I DEND PEF
Sbjct: 463 GEL-LLTHPVDYEGEHHLYHLLLKAVEAESALSSVAEVMVHITDENDCSPEF 513
Score = 35.9 bits (79), Expect = 8.6
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 819 EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT-GGLSSEA 877
E T+A YTL G+E F VD +TG++ G L K+ Y +++ A D G S A
Sbjct: 342 ENTSAGVSYTLIAGGEERFQVDVDTGIIVTTGLPLVWNKE--YVVTVQASDEYGNKSPFA 399
Query: 878 ELIIMIG 884
+ I++G
Sbjct: 400 SISILVG 406
>UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 2676
Score = 152 bits (369), Expect = 6e-35
Identities = 180/687 (26%), Positives = 296/687 (43%), Gaps = 73/687 (10%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A + Y +ISGN + F +D G + + LD E F L + A+
Sbjct: 1993 AQVTYSIISGNKGRAFYVDPFTGVISVASADALDYE---STKNFRLHLVATPQGWVSLNG 2049
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS---VLQVMATDKDQGENGEFTYQL 345
++I ++D NDN P F + E+ F V++V ATD D G NG+ TY +
Sbjct: 2050 YMILDINVIDRNDNSPAFHPSNMLAQLAEDT-GAFKPRFVVKVTATDVDSGTNGKVTYSI 2108
Query: 346 --DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKW 403
+ G F+ID +G +T +LDRE +S + + ++ T + +
Sbjct: 2109 WTGNEAGVFTIDSTTGEITTAK--LLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVT- 2165
Query: 404 RRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSN 463
L N PL + T+T + VT + A D + +
Sbjct: 2166 ---DLNDNPPLFDPLSEVNIREDTRTGAV--------------VTSVVATDTDK----ES 2204
Query: 464 LYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA 523
+++KS + G I +V A D D G N + Y T++ I +KI+ +TG +S
Sbjct: 2205 RLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQID--YKIDADTGVISAR 2262
Query: 524 ESPILEGRHALF---VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
+ + R + V+A DQ P +L V I +TR K ++P + G
Sbjct: 2263 RTIDVRIRDSFIQIPVQAMDQGVPPQR---ALVYVRIIITREPKF---ELPSYFGK---- 2312
Query: 581 WVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSR 637
V N +GTSV +RV D +SY++ E F + +RSGVI+V L
Sbjct: 2313 -VPENAMMGTSVLTVRVTDNAAGLPLGRISYNI----ENSNYFRIGQRSGVISVNKPLDY 2367
Query: 638 YNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
+ + A+ + A + + ++V DVNDE+ V + + + + S G
Sbjct: 2368 ETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGY------MAQWSEGIP 2421
Query: 697 IGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMT 755
+G I ++ +G G V F I + D + G I TQ+ LD E + ++
Sbjct: 2422 VGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVS 2481
Query: 756 VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE-HATYEGFIMENSKIGTEIKMDNIIKA 814
V A ++G VTI + D NDNPPVF + ++EN + + + I A
Sbjct: 2482 VRAT-DEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYE---INA 2537
Query: 815 TDADEGTNALFMYTLF-GEGKEMFDVDENTG-VVKFIGDSLDREKKIMYKLSLVARDTGG 872
TD D G NA +T+ G G+ +F +D+ +G + I + Y L++ A D G
Sbjct: 2538 TDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGN 2597
Query: 873 --LSSEAELIIMIGDENDNKPEFNQIE 897
LSS +I+ + DE++ P FN+++
Sbjct: 2598 PPLSSNITIIVNVADEDEYDPSFNRMD 2624
Score = 144 bits (350), Expect = 1e-32
Identities = 194/758 (25%), Positives = 309/758 (40%), Gaps = 123/758 (16%)
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G+P +E +GVIT L R Y+ V V V+V D+ND
Sbjct: 2 GIPADLEYNAGVITTKTVLDREKVSAYNLTIVEFSTPPKSYTVL---VYVQDLNDNSPSF 58
Query: 677 LKGAHSPIIFHVKENSAGA---AIGQIFHTNMSSIYGNGTGNVR--FLIANQQDVTDDIA 731
++G + ++ + A+ F +N + Y +GNV F + +++D D+
Sbjct: 59 VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDL- 117
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A+ + +DRE+ D Y + + A + G + G +++I +ED NDN P F + +
Sbjct: 118 YADLVVNASSIGVDRERLDSYVLNISAS-DGGNPANHGFLRLSITVEDTNDNKPEFSNVS 176
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDENTGVVKFI 849
Y G I EN +GT I + A+D D GTNA Y++ + + +F + TGV+
Sbjct: 177 YSGTIPENIDVGTSILQ---VSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVI-VN 232
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LD E K Y + + A D K +Q+ ++ VRI
Sbjct: 233 NVRLDYEAKRSYLIVVKAED--------------------KGSSHQLSSSAIVRIE---- 268
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
+++V N LG + + EN IGT + +++ D DSG NG++
Sbjct: 269 --------VLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVT 320
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--L 1025
D ++ V+N+ + V +SL E+ F L +D G+
Sbjct: 321 LEG----------GDGYFSMKFDVLNDE-SIIAVGQSLDRETHDHFFLKAVCIDKGDPPR 369
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
S R+ V DVND P F + Y V E ++ V+A D DFG N+ L Y I
Sbjct: 370 TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIA 429
Query: 1086 PSDTDLP----FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
+ F I P +G+++ +LDRE + +LTV+ D G
Sbjct: 430 NTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRG-SPPLSDNCSVIVNL 488
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA 1201
D NDN P F S++N A++ EN+P G+ V ++ A
Sbjct: 489 TDSNDNDPYF---------------NQSSYN-----------ASLFENSPSGSPVVQLLA 522
Query: 1202 NDTDFIGNGNGLILYS---------LPQRK----NQQNLGLPSLSSTAILMVTV------ 1242
D D IG N LILYS L RK N + L SS +
Sbjct: 523 QDPD-IGE-NSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRS 580
Query: 1243 ADVPDEVEMSD----KPVFISRYYELEIEENVNAPVELVSLN-LTEHYENFKMRYYILNE 1297
+ V ++D +PVF Y +E EN + L + F + +I+ +
Sbjct: 581 CNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ 640
Query: 1298 NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ D F +D +G + L + DRE +D Y + V+A
Sbjct: 641 GNAD--EVFSVD-GSGLITLAKLLDRETQDNYLLTVKA 675
Score = 144 bits (350), Expect = 1e-32
Identities = 190/732 (25%), Positives = 309/732 (42%), Gaps = 74/732 (10%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ--NGMVLY 497
M+ V V + + D N++ P F + YE + N ++ V A D D + NG V Y
Sbjct: 1835 MAIVPVRIKIEDKNNHAPQFTKTP-YEVHIFPNTSASALVTMVTATDADTDKSTNGKVTY 1893
Query: 498 DLQRTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
L + N T S F + NTG+V S S +GRHAL++ A D +P R Y + +
Sbjct: 1894 RLDDSKNST--SLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDH-GSPPLRGYGIVQI 1950
Query: 556 TIEVTRGTKGN-KPDIPDFMG-APYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
I GN + D P F+ P + N +G+ + +R A V+Y ++ G
Sbjct: 1951 VI-------GNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR-ASSDAQVTYSIISG 2002
Query: 614 YEEGVPFAVEERSGVITV--VDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVN 670
+G F V+ +GVI+V D L + + VA + +L+ ++V+D N
Sbjct: 2003 -NKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRN 2061
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D S ++ + E++ + + + G V + I +
Sbjct: 2062 DNSPAF---HPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFT 2118
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G I T K LDRE + + VI + G+ + QV + + D NDNPP+F+
Sbjct: 2119 IDSTTGEITTAKLLDRETTASFDL-VIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPL 2177
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF-MYTLFGEGKEMFDV---DENTGVV 846
+ E I E+++ G + + ATD D+ + + + + G + V D+++G
Sbjct: 2178 S-EVNIREDTRTGAVV---TSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSN 2233
Query: 847 KFIGDS--LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
I S + +I YK+ DTG +S+ + + I D F QI + +
Sbjct: 2234 AQIKYSFPITNSDQIDYKID---ADTGVISARRTIDVRIRD------SFIQIPVQA---M 2281
Query: 905 HRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN- 963
+ + I + + KF L G +PEN +GT+++ + D +GL
Sbjct: 2282 DQGVPPQRALVYVRIIITREPKFELP-SYFGK---VPENAMMGTSVLTVRVTDNAAGLPL 2337
Query: 964 GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD 1021
G+I Y +E YF I +R G + V + L E++ F L +SA+D
Sbjct: 2338 GRISYN----------------IENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAID 2381
Query: 1022 GGNLNDNISVRVF--VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
+ + V V+ V DVND PVF ++ Y E ++ V A D D G N
Sbjct: 2382 DTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGR 2441
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
+ + IQ D F I TGV+ LD ET + ++V A D G
Sbjct: 2442 VWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEG-SPPMHTDVSVTI 2500
Query: 1140 XXXDVNDNSPKF 1151
D+NDN P F
Sbjct: 2501 RVLDLNDNPPVF 2512
Score = 138 bits (333), Expect = 1e-30
Identities = 134/486 (27%), Positives = 222/486 (45%), Gaps = 42/486 (8%)
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
++ K I++ + S +V+V + D NDNNP F ++ Y F +K N V T +G V
Sbjct: 980 EEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQAS-YAFFVKENEPVATYLGAV 1038
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD 540
A D D G NG V Y T + F ++ TG ++ ++ E + + + A+D
Sbjct: 1039 SASDSDEGSNGHVTYRFD-----TQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATD 1093
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
++P + + V+ +V + P F Y V ++ +G+S+ + D
Sbjct: 1094 GGSSPRVDKTQVTVIVRDVNDCS-------PKFSKNKYSVTVNEDLPVGSSLLTLIATDD 1146
Query: 601 FEQ---NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS 657
+Q +D++Y ++ G + F++ + +GV+T+V L R + VA + N S
Sbjct: 1147 DQQGPNSDITYMIVAGPKA---FSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQS 1203
Query: 658 I--VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
+ +T ++V+DVND V + + ++ G+ + + + G
Sbjct: 1204 LETITYIEINVLDVNDNYPVFINETTFKTV--PEKLPIGSVVAAVLAVDSDQ---GDNGK 1258
Query: 716 VRFLIAN-QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ-V 773
VR+ I N D T I G I T + LD E + Y + V A + G YQ V
Sbjct: 1259 VRYKIVNGNTDGTFKIN-ETTGVISTLRALDFEVTNRYVLRVSAT-DMGKKQQKTSYQLV 1316
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
TIY+ED NDN P F+ +I EN I T + IKA D D G N+ YT+ +
Sbjct: 1317 TIYVEDANDNRPTFDKNPIITWIYENVPINTNV---TTIKAHDDDSGLNSRIWYTIDSQS 1373
Query: 834 -KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG-----GLSSEAELIIMIGDEN 887
+ F ++ TG+++ +DRE+ Y L + A D L + A L I+I D N
Sbjct: 1374 PRAHFKINSETGLIQ-TTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLN 1432
Query: 888 DNKPEF 893
DN P+F
Sbjct: 1433 DNAPKF 1438
Score = 133 bits (322), Expect = 3e-29
Identities = 185/738 (25%), Positives = 300/738 (40%), Gaps = 71/738 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F N+ + + D NDN PVF S LY ++ GT I + A D D G NG ++Y L
Sbjct: 1732 AFANITIFIEDQNDNPPVFQQS-LYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL- 1789
Query: 501 RTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
SN T + I+ TG V A ++ + F A DQ +P +A+V +
Sbjct: 1790 --SNDTY-GVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPK-----MAIVPVR 1841
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYDLLHGY 614
+ K N P F PYE + N V + DA V+Y L
Sbjct: 1842 IKIEDKNNHA--PQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSK 1899
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDE 672
F VE +G + S + + +A +++ + + V +V ++ D+
Sbjct: 1900 NSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIA-EDHGSPPLRGYGIVQIVIGNIQDD 1958
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L +P + ENS +G T + + + N+
Sbjct: 1959 PPRFLN--QTPARVSIPENSK---VGSYITTVRARASSDAQVTYSIISGNKGRAFYVDPF 2013
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++ + LD E +R+ ++A +G +S G + I + D NDN P F +
Sbjct: 2014 TGVISVASADALDYESTKNFRLHLVAT-PQGWVSLNGYMILDINVIDRNDNSPAFHPSNM 2072
Query: 793 EGFIMENSKIGTEIKMDNIIK--ATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
+ E++ K ++K ATD D GTN Y+++ G +F +D TG +
Sbjct: 2073 LAQLAEDTGA---FKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEIT-T 2128
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
LDRE + L + D+G S+ ++ +++ D NDN P F+ + E V I +
Sbjct: 2129 AKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSE---VNIRED 2185
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPL-FLIPENIPIGTTIIKLNALDLDSGLNGQI 966
T+ G + V A D D+ L + + G I++++A D DSG N QI
Sbjct: 2186 TR----TGAVVTSV-----VATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQI 2236
Query: 967 RYEF---NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG 1023
+Y F NS+ K+ AD VI+ R + R +S ++ + A+D G
Sbjct: 2237 KYSFPITNSDQI--DYKIDADT------GVISARRTIDVRIR----DSFIQIPVQAMDQG 2284
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTY 1082
V+V+ + P F+ Y V E + V TD G ++Y
Sbjct: 2285 VPPQR--ALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISY 2342
Query: 1083 FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
I+ S+ F I +GV+SVN LD ET+ +++L V A D+
Sbjct: 2343 NIENSNY---FRIGQRSGVISVNKPLDYETKRRFLLVVSAIDD-TAPSKPVRVPVYINVS 2398
Query: 1143 DVNDNSPKFYAFDELLEW 1160
DVND P F + +W
Sbjct: 2399 DVNDEKPVFGQSGYMAQW 2416
Score = 130 bits (314), Expect = 3e-28
Identities = 124/467 (26%), Positives = 211/467 (45%), Gaps = 34/467 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
++L + +++ + D NDN P FV NL + M+ + + A+DPD GQ G V
Sbjct: 1416 DRLYNTATLKIIIQDLNDNAPKFVSRNL-TYVMEDEP-FNFQVTSITALDPDTGQGGNVE 1473
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAV 554
Y + T F ++ TG + + S E ++ L + A+D + P V
Sbjct: 1474 YRIVSPD----TGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNV 1529
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH 612
V ++V + P P+F + V N GTSV ++ D+ +++Y +
Sbjct: 1530 VVVDVN-----DNP--PEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPS 1582
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-TNATVHVVDVND 671
G E F++++ SG+I L R + Y A + + T+ ++V+D ND
Sbjct: 1583 GVEMD-KFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRND 1641
Query: 672 ERGVLLKGAHSPII-FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ SP++ V ENS I + ++ YGN T + +++ D I
Sbjct: 1642 NPPKFI----SPVVTLKVPENSPARLIYTLTVQDLD--YGNNTKVLYSIMSGNTDGAFTI 1695
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
G + T LDRE + Y+++V A+ A +TI+IED+NDNPPVF+ +
Sbjct: 1696 G-RSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTA-FANITIFIEDQNDNPPVFQQS 1753
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y I E + GT I + A+D D G+N +YTL + ++ +D TG+V +
Sbjct: 1754 LYSSTISELTPPGTSILN---LTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIV-YSA 1809
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFNQ 895
+ K Y +A+D G A + I I D+N++ P+F +
Sbjct: 1810 ARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTK 1856
Score = 124 bits (300), Expect = 1e-26
Identities = 123/462 (26%), Positives = 205/462 (44%), Gaps = 25/462 (5%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
F+ + +T+ D NDN P F SN+ Y ++ N VGT I +V A D D+G N + Y ++
Sbjct: 155 FLRLSITVEDTNDNKPEF--SNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIE 212
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
S+ F I+P TG + E + + + + S + S A+V IEV
Sbjct: 213 THSDPQAI--FGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVL 270
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEE--G 617
N P I + V N IGT V ++ V+DA + ++ L G +
Sbjct: 271 -DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFS 329
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVL 676
+ F V +I V L R + +AV + + + + + ++V DVND
Sbjct: 330 MKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKF 389
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI---AI- 732
+ + ++ EN+ + I + + +G+ + V + IAN + + AI
Sbjct: 390 DRHTYETRVW---ENATVNTLVAIVNA-VDQDFGSNSELV-YTIANTTESRSYLHWFAID 444
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G I T LDRE+ +TV+ ++G + V + + D NDN P F ++Y
Sbjct: 445 PSSGMITTATDLDREQIPQVVLTVLVH-DRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSY 503
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ ENS G+ + + A D D G N+L +Y++ F +D G+V +
Sbjct: 504 NASLFENSPSGSPVVQ---LLAQDPDIGENSLILYSILTPNTPFF-LDPRKGLVTN-SRT 558
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
LD E + Y + A D GG S A + + + D NDN+P F+
Sbjct: 559 LDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFD 600
Score = 122 bits (293), Expect = 1e-25
Identities = 134/473 (28%), Positives = 215/473 (45%), Gaps = 38/473 (8%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS-NLTITS 509
D ND P F + YE + NA V T++ V AVD D G N ++Y + T+ + +
Sbjct: 381 DVNDCAPKF-DRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLH 439
Query: 510 PFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F I+P++G ++ A E + L V D+ + P S+ +V + T N
Sbjct: 440 WFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSV-IVNL-----TDSND 493
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFAVEER 625
D P F + Y + N G+ V Q+ D E + + Y +L PF ++ R
Sbjct: 494 ND-PYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSIL---TPNTPFFLDPR 549
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDVNDERGVLLKGAHSP 683
G++T L + Y F+ VA + S NATVHV D+ND + V ++S
Sbjct: 550 KGLVTNSRTLDHEVQSSYTFQ-VAATDGGGRSC--NATVHVSLTDLNDNQPVFDPSSYS- 605
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP 743
+ + + G +I Q+ + S T RF+I Q + + ++ G I K
Sbjct: 606 -VEYFENTRIGQSICQLKAIDRDSPKFAIT---RFII-EQGNADEVFSVDGSGLITLAKL 660
Query: 744 LDREKRDVYRMTVIAEFNKGVIS-GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE +D Y +TV A G S I +T+ D ND PP+F A Y I E+S+
Sbjct: 661 LDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVL--DVNDEPPIFSKAEYNFTIQEHSQA 718
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
+ + + A D+GTNA +Y++ + + +TG + ++ +D EK
Sbjct: 719 ---LSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTL-YLQSEVDHEKIPSLY 774
Query: 863 LSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
L++ A+D G L A + I + D NDN P+FN + VR+ +T + T
Sbjct: 775 LTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFN--SSSILVRLPEDTPIGHT 825
Score = 118 bits (285), Expect = 9e-25
Identities = 128/458 (27%), Positives = 210/458 (45%), Gaps = 36/458 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V V L D+NDN+P F S+ Y S+ N+ G+ + ++ A DPD+G+N ++LY +
Sbjct: 483 SVIVNLTDSNDNDPYFNQSS-YNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI---- 537
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
LT +PF ++P G V+ + + E + + + + A R A V + +T
Sbjct: 538 -LTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVA---ATDGGGRSCNATVHVSLT-DL 592
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGVPFAV 622
N+ P F + Y N IG S+ Q++ D ++ ++ F+V
Sbjct: 593 NDNQ---PVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV 649
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVAL----QENANLSIVTNATVHVVDVNDERGVLLK 678
+ SG+IT+ L R + Y A+ Q++ N +IV + V+DVNDE + K
Sbjct: 650 -DGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIV---NITVLDVNDEPPIFSK 705
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA-IAEDGT 737
++ F ++E+S A+ I H + S GT N + + + TD+I I GT
Sbjct: 706 AEYN---FTIQEHS--QALSVIGHVHAIS-RDKGT-NAEVVYSISKGNTDNIVLINSTGT 758
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++ Q +D EK +TV A+ +KG G VTI + D NDN P F ++ +
Sbjct: 759 LYLQSEVDHEKIPSLYLTVQAK-DKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLP 817
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
E++ IG + DAD G ++L +F++D NTG +
Sbjct: 818 EDTPIGHTF---YTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNS 874
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
Y L + A+D G SS A L + + D ND P F
Sbjct: 875 ARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVF 912
Score = 113 bits (271), Expect = 5e-23
Identities = 130/487 (26%), Positives = 208/487 (42%), Gaps = 44/487 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLY--EFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
QL S V + +LD NDNNPV S + + NA +GT + +V D D G+NG V
Sbjct: 258 QLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEV 317
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA----SDQPANPSERRYS 551
L+ + F + + ++V +S E F++A P +E+ +
Sbjct: 318 NVTLEGGDGY-FSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFR 376
Query: 552 LAVVTIEVTRGTKGNKPD-IPDFMGAPYEFWVGSNVGIGTSVGQIR-VNDAFEQN-DVSY 608
+ V G+ D P F YE V N + T V + V+ F N ++ Y
Sbjct: 377 INV----------GDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVY 426
Query: 609 DLLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATV 664
+ + E FA++ SG+IT DL R P + + LS + V
Sbjct: 427 TIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIV 486
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
++ D ND + +++ +F ENS +G+ + Q+ + I N L N
Sbjct: 487 NLTDSNDNDPYFNQSSYNASLF---ENSPSGSPVVQLLAQD-PDIGENSLILYSILTPNT 542
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D G + + LD E + Y V A G A ++ + + D NDN
Sbjct: 543 PFFLD----PRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH---VSLTDLNDN 595
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDEN 842
PVF+ ++Y EN++IG I +KA D D A+ + + G E+F VD
Sbjct: 596 QPVFDPSSYSVEYFENTRIGQSICQ---LKAIDRDSPKFAITRFIIEQGNADEVFSVD-G 651
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQIEENS 900
+G++ + LDRE + Y L++ A D GG S + I+ I D ND P F++ E N
Sbjct: 652 SGLIT-LAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNF 710
Query: 901 KVRIHRE 907
++ H +
Sbjct: 711 TIQEHSQ 717
Score = 109 bits (261), Expect = 8e-22
Identities = 129/486 (26%), Positives = 210/486 (43%), Gaps = 68/486 (13%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN P+ T + ++A D D G NG + Y F+++V F+++++
Sbjct: 1023 FFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQV---------------AQFIVDKQ 1067
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + ++ L E++ + +I A DGG+ D V V V+DVND P F K Y+
Sbjct: 1068 TGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVT 1127
Query: 1054 VEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
V E L + ATD D G N+++TY I F ++ +TGVL++ LDRE
Sbjct: 1128 VNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPK--AFSLNQVTGVLTLVSPLDREV 1185
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY---AFDELLEWKHP------ 1163
++IL VVA D G DVNDN P F F + E K P
Sbjct: 1186 THRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPE-KLPIGSVVA 1244
Query: 1164 -----EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
++D+ N ++ T + N G ++ + A D + + N L + +
Sbjct: 1245 AVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTG-VISTLRALDFE-VTNRYVLRVSAT 1302
Query: 1219 PQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
K QQ +S ++ + V D D DK I+ YE +N V +
Sbjct: 1303 DMGKKQQK------TSYQLVTIYVEDANDNRPTFDKNPIITWIYE---NVPINTNVTTIK 1353
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ + N ++ Y I +++ R F I+ G + DRE Y + VRA Q
Sbjct: 1354 AHDDDSGLNSRIWYTIDSQSP---RAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQ 1410
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
++ + +Y A +K++ I+D+NDN+PKF + N +T + PF
Sbjct: 1411 AFTEQ--DRLYNTA----------TLKII--IQDLNDNAPKFVSRN---LTYVMEDEPFN 1453
Query: 1399 YQVMQL 1404
+QV +
Sbjct: 1454 FQVTSI 1459
Score = 106 bits (254), Expect = 5e-21
Identities = 127/518 (24%), Positives = 210/518 (40%), Gaps = 42/518 (8%)
Query: 412 APLEKTTYVFPDKVGTKTENIEYYDEQLMSF------VNVEVTLLDANDNNPVFVPSNLY 465
A LE V K E + Y+ ++ F V V + D NDN+P FV
Sbjct: 5 ADLEYNAGVITTKTVLDREKVSAYNLTIVEFSTPPKSYTVLVYVQDLNDNSPSFVRGTSA 64
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS---- 521
+ + N K K+ AVD D G N Y + + + G +
Sbjct: 65 KLVVFENDK--DFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLV 122
Query: 522 VAESPILEGR-----HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGA 576
V S I R + L + ASD NP+ + +T+E T K P+F
Sbjct: 123 VNASSIGVDRERLDSYVLNISASDG-GNPANHGFLRLSITVEDTNDNK------PEFSNV 175
Query: 577 PYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDD 634
Y + N+ +GTS+ Q+ +D ++ Y + + F + +GVI
Sbjct: 176 SYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVR 235
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVLLKGAHSPIIFHVKENS 692
L + Y A + ++ + ++A V V+DVND V+ + V EN+
Sbjct: 236 LDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENA 295
Query: 693 A-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDV 751
G + ++ ++ S NG NV + + ++ I + LDRE D
Sbjct: 296 TIGTQVARVSVSDADS-GKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDH 354
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
+ + + +KG I + D ND P F+ TYE + EN+ + T + I
Sbjct: 355 FFLKAVC-IDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVA---I 410
Query: 812 IKATDADEGTNALFMYTLFGEGKEM-----FDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ A D D G+N+ +YT+ + F +D ++G++ D LDRE+ L+++
Sbjct: 411 VNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATD-LDREQIPQVVLTVL 469
Query: 867 ARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
D G LS +I+ + D NDN P FNQ N+ +
Sbjct: 470 VHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASL 507
Score = 103 bits (247), Expect = 4e-20
Identities = 132/456 (28%), Positives = 197/456 (43%), Gaps = 66/456 (14%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN IG +I +L A+D DS R+ +A EV F + + G +
Sbjct: 610 ENTRIGQSICQLKAIDRDSPKFAITRFIIEQ----------GNADEV---FSV-DGSGLI 655
Query: 1002 IVARSLPPESE--FRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+A+ L E++ + L + A+DGG D+++ V + V DVND P+F K YNF ++E
Sbjct: 656 TLAKLLDRETQDNYLLTVKAVDGGG-QDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQE 714
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
V+G V A D G NA + Y I +TD I+ TG L + E+D E
Sbjct: 715 HSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINS-TGTLYLQSEVDHEKIPSL 773
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
LTV A+D G D+NDNSP+F + L+ + PE D H F +V
Sbjct: 774 YLTVQAKDKG-TPPLFGYANVTIAVIDINDNSPQFNSSSILV--RLPE-DTPIGHTFYTV 829
Query: 1177 MMIPVYKATI-EENAPIGTTVAKVFAND--------TDFIGNGNGLILYSLPQRKNQQNL 1227
+ + + + + +F D T I GN Y+LP + Q+
Sbjct: 830 SVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQ--AQDG 887
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHY 1285
G P SSTA+L + V DV D PVF + Y + E ++ + T +
Sbjct: 888 GSPPRSSTAMLELKVVDVNDY-----SPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSG 942
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRAERQKYSREL 1344
EN ++ Y ++ DT F + RNG ++S DRE + Y + V A
Sbjct: 943 ENGRISYAFDSKVDTS---KFGL--RNGGKIFIKSKLDREDIEEYNLKVIA--------- 988
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ + DVKV+V DVNDN+P F
Sbjct: 989 ------IDHGTPRRSSSADVKVIV--DDVNDNNPHF 1016
Score = 102 bits (244), Expect = 9e-20
Identities = 120/459 (26%), Positives = 202/459 (44%), Gaps = 32/459 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+E+ ++D ND +PVF + +++ +I +V A D D G+NG + Y +
Sbjct: 898 LELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNII-EVVATDVDSGENGRISYAFDSKVD 956
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
TS F + N G + + E + L V A D + + RR S A V + V
Sbjct: 957 ---TSKFGLR-NGGKIFIKSKLDREDIEEYNLKVIAID---HGTPRRSSSADVKVIVDDV 1009
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-FA 621
N P F A Y F+V N + T +G + +D+ E ++ + + ++ V F
Sbjct: 1010 NDNN----PHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGH--VTYRFDTQVAQFI 1063
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLKGA 680
V++++G IT L R + Y F VA ++ + T TV V DVND K
Sbjct: 1064 VDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNK 1123
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+S + ++ G+++ + T+ G + ++A + + + G +
Sbjct: 1124 YSVTVN--EDLPVGSSLLTLIATDDDQ-QGPNSDITYMIVAGPKAFSLNQVT---GVLTL 1177
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
PLDRE + + V+A G S I + I + D NDN PVF + T + E
Sbjct: 1178 VSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKL 1237
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKI 859
IG+ + + A D+D+G N Y + G F ++E TGV+ + +LD E
Sbjct: 1238 PIGSVVA---AVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTL-RALDFEVTN 1293
Query: 860 MYKLSLVARDTGGLSSEAE---LIIMIGDENDNKPEFNQ 895
Y L + A D G + + I + D NDN+P F++
Sbjct: 1294 RYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDK 1332
Score = 99 bits (238), Expect = 5e-19
Identities = 108/410 (26%), Positives = 175/410 (42%), Gaps = 38/410 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+PI T + + A D DSGLN +I Y +S+ + +F IN G
Sbjct: 1339 IYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQ-------------SPRAHFKINSETG 1385
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG-----NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ + E SE+ L + A D L + ++++ ++D+ND+ P F +
Sbjct: 1386 LIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTY 1445
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+E+ + +V + A D D GQ N+ Y I DT F + TGVL + G LD E
Sbjct: 1446 VMEDEPFNFQVT-SITALDPDTGQGGNVEYRIVSPDTG-KFSLDLKTGVLKLIGSLDYED 1503
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+Y L + A D G DVNDN P+F +L E +
Sbjct: 1504 VPQYTLHISATDLG-SPPLTSYQLFNVVVVDVNDNPPEFTR--DLFIGTVSE----NKPT 1556
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL-YSLPQRKNQQNLGLPS 1231
SV+ + Y NA + ++ D I +GLI+ S+ R+ + L
Sbjct: 1557 GTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTV 1616
Query: 1232 LSSTAILMVTVADVPDEVEMSDK----PVFISRYYELEIEENVNAP-VELVSLNLTEHYE 1286
++ V+ + + D+ P FIS L++ EN A + +++ ++
Sbjct: 1617 HATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQDLDYGN 1676
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
N K+ Y I++ N TD F I G L DRE K +Y++ V+A+
Sbjct: 1677 NTKVLYSIMSGN-TD--GAFTIGRSTGELSTTTKLDRETKASYQLSVQAK 1723
Score = 99.5 bits (237), Expect = 6e-19
Identities = 93/323 (28%), Positives = 137/323 (42%), Gaps = 28/323 (8%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL------T 129
Q ++Y VT+Y+ED NDN P F P + E P L T
Sbjct: 1309 QKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYT 1368
Query: 130 IPLTVPRG-LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKV 187
I PR I + P YS+ V D + + L +
Sbjct: 1369 IDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIII 1428
Query: 188 LDYDAGDKEF---QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
D + +F L + + + ++ I A+D D G G + Y ++S + K F
Sbjct: 1429 QDLNDNAPKFVSRNLTYVMEDEPFNFQVT---SITALDPDTGQGGNVEYRIVSPDTGK-F 1484
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
SLD G L L LD + + L + A+ L +P T+ + ++D+NDN P
Sbjct: 1485 SLDLKTGVLKLIGSLDYE-----DVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPP 1539
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPRSGW 360
EF D + ++ EN P G SV++V A D+D G N E TY + P G FSID SG
Sbjct: 1540 EFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSI--PSGVEMDKFSIDKHSG- 1596
Query: 361 LTVRNQTVLDREAHSSLRMKVYA 383
L V N ++LDRE + + V+A
Sbjct: 1597 LIVTN-SILDREKKDTYFLTVHA 1618
Score = 95.9 bits (228), Expect = 8e-18
Identities = 117/465 (25%), Positives = 190/465 (40%), Gaps = 37/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + NV + ++D NDN+P F S++ + + +G V D D G G V +
Sbjct: 787 LFGYANVTIAVIDINDNSPQFNSSSIL-VRLPEDTPIGHTFYTVSVFDADSGVLGRVSFS 845
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA----LFVEASDQPANPSERRYSLAV 554
L + F ++ NTG +S+ + I G A L V+A D + P L +
Sbjct: 846 LLSNPG----TLFNLDSNTGALSLTKL-IDYGNSARSYTLPVQAQDGGSPPRSSTAMLEL 900
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLH 612
++V + P F Y V +++ ++ D+ E +SY
Sbjct: 901 KVVDVNDYS-------PVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISY-AFD 952
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
+ F + G I + L R + Y+ + +A+ S + V V DVND
Sbjct: 953 SKVDTSKFGL-RNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVND 1011
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ +++ F VKEN A + S NG RF V I
Sbjct: 1012 NNPHFQQASYA---FFVKENEPVATYLGAVSASDSDEGSNGHVTYRF----DTQVAQFIV 1064
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G I T + LDRE + Y +++A + G QVT+ + D ND P F
Sbjct: 1065 DKQTGKITTSQVLDREAKASYVFSIVAT-DGGSSPRVDKTQVTVIVRDVNDCSPKFSKNK 1123
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + E+ +G+ + +I D +G N+ Y + G + F +++ TGV+ +
Sbjct: 1124 YSVTVNEDLPVGSSLL--TLIATDDDQQGPNSDITYMIVA-GPKAFSLNQVTGVLTLV-S 1179
Query: 852 SLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEF 893
LDRE + L +VA D GG L + + I + D NDN P F
Sbjct: 1180 PLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVF 1224
Score = 95.5 bits (227), Expect = 1e-17
Identities = 62/184 (33%), Positives = 95/184 (51%), Gaps = 10/184 (5%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS---VNGSLFLEKELDLDA--EHNLQ 268
F + + A+D D G +T Y ++SGN +F L S +G L+ + ++ + +
Sbjct: 75 FRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRER 134
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+++VL + AS NP R+ I + D NDN PEF Y+ +I EN+ G S+LQV
Sbjct: 135 LDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQV 194
Query: 329 MATDKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A+DKD G N E Y ++ DP+ F I P +G + N LD EA S + V A++
Sbjct: 195 SASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTG--VIVNNVRLDYEAKRSYLIVVKAED 252
Query: 386 TNPS 389
S
Sbjct: 253 KGSS 256
Score = 94.7 bits (225), Expect = 2e-17
Identities = 70/215 (32%), Positives = 107/215 (49%), Gaps = 23/215 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E P + II++ A D+DSG NG+I Y F+S+V + ++ + N G +
Sbjct: 923 ETTPPDSNIIEVVATDVDSGENGRISYAFDSKV------------DTSKFGLRNG--GKI 968
Query: 1002 IVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ L E E+ L + A+D G + + V+V V DVND+ P F++ Y F V+E
Sbjct: 969 FIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKEN 1028
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-PFEISPLTGVLSVNGELDRETEDKY 1116
+ LG V A+D+D G N ++TY DT + F + TG ++ + LDRE + Y
Sbjct: 1029 EPVATYLGAVSASDSDEGSNGHVTYRF---DTQVAQFIVDKQTGKITTSQVLDREAKASY 1085
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ ++VA D G DVND SPKF
Sbjct: 1086 VFSIVATDGG-SSPRVDKTQVTVIVRDVNDCSPKF 1119
Score = 94.3 bits (224), Expect = 2e-17
Identities = 98/369 (26%), Positives = 159/369 (43%), Gaps = 37/369 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G +++Y V + DVNDN P F + TV E PTG G + +
Sbjct: 1517 GSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAEL 1576
Query: 131 PLTVPRGLTIFK---DIRA--------FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
++P G+ + K D + DR+K +T VH + VS + S
Sbjct: 1577 TYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVS------YPFRVSST 1630
Query: 180 PVLLLRKVLDYDAGDKEF--QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
V + V+D + +F +V + + +++ + D D G + Y ++S
Sbjct: 1631 SVRI--NVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQ--DLDYGNNTKVLYSIMS 1686
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN F++ G L +LD + + + Q L VQA + P TA A + I +
Sbjct: 1687 GNTDGAFTIGRSTGELSTTTKLDRETKASYQ-----LSVQAKDITPPYYTAFANITIFIE 1741
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDP 356
D NDN P F+ Y+ +I E P G S+L + A+DKD G NG Y L +D G +SID
Sbjct: 1742 DQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDS 1801
Query: 357 RSG--WLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL 414
R+G + R +T + +E + K ++ ++V + K P T P
Sbjct: 1802 RTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIE--DKNNHAPQFTKTPY 1859
Query: 415 EKTTYVFPD 423
E ++FP+
Sbjct: 1860 E--VHIFPN 1866
Score = 91.9 bits (218), Expect = 1e-16
Identities = 127/490 (25%), Positives = 195/490 (39%), Gaps = 66/490 (13%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F+ +PE +PIG+ + + A+D D G NG++RY+ +
Sbjct: 1215 LDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNG-------- 1266
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNIS---VRVFVK 1036
+ D F INE G + R+L E + + L +SA D G S V ++V+
Sbjct: 1267 NTDGT-----FKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVE 1321
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
D ND+ P F K + E + + A D D G N+ + Y I F+I+
Sbjct: 1322 DANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKIN 1381
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXX--XXXXXXXXXXXXXXDVNDNSPKFYAF 1154
TG++ +DRE +Y L V A D D+NDN+PKF +
Sbjct: 1382 SETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVS- 1440
Query: 1155 DELLEWKHPEADELSNHNFESVMMI--PVYKATIEENAPIGTTVAKVFAND--TDFIGNG 1210
+ DE N S+ + + E + K F+ D T +
Sbjct: 1441 ---RNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGK-FSLDLKTGVLKLI 1496
Query: 1211 NGLILYSLPQ---RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
L +PQ + +LG P L+S + V V DV D + +FI E
Sbjct: 1497 GSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSE---N 1553
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
+ V V+ + N ++ Y I + + D F ID +G + DRE KD
Sbjct: 1554 KPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD---KFSIDKHSGLIVTNSILDREKKD 1610
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPL 1387
TY + V A Y P + V + + D NDN PKF + P+
Sbjct: 1611 TYFLTVHATGVSY----PFRV-------------SSTSVRINVMDRNDNPPKFIS---PV 1650
Query: 1388 VT-AIPTTAP 1396
VT +P +P
Sbjct: 1651 VTLKVPENSP 1660
Score = 88.2 bits (209), Expect = 2e-15
Identities = 99/407 (24%), Positives = 162/407 (39%), Gaps = 43/407 (10%)
Query: 1015 LNISALDGGNLNDN--ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
LNISA DGGN ++ + + + V+D ND+ P F Y+ + E + +V A+D
Sbjct: 140 LNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDK 199
Query: 1073 DFGQNANLTYFIQP-SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
D G NA + Y I+ SD F I P TGV+ N LD E + Y++ V A D G
Sbjct: 200 DIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQL 259
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
DVNDN+P + L + + + V + V A +N
Sbjct: 260 SSSAIVRIEVLDVNDNNPVIHV-SYTLGGSYQVTENATIGT--QVARVSVSDADSGKNGE 316
Query: 1192 IGTTVA---KVFANDTDFIGNGNGLILYSLPQRKNQQNL---------GLPSLSSTAILM 1239
+ T+ F+ D + + + + + R+ + G P ++
Sbjct: 317 VNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFR 376
Query: 1240 VTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEND 1299
+ V DV D D+ + +R +E VN V +V+ + N ++ Y I N +
Sbjct: 377 INVGDVNDCAPKFDRHTYETRVWE---NATVNTLVAIVNAVDQDFGSNSELVYTIANTTE 433
Query: 1300 T-DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPV-AEDVLE 1357
+ F IDP +G + DRE ++P ++ V D
Sbjct: 434 SRSYLHWFAIDPSSGMITTATDLDRE------------------QIPQVVLTVLVHDRGS 475
Query: 1358 GMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ V+V + D NDN P F + ++ +P G V+QL
Sbjct: 476 PPLSDNCSVIVNLTDSNDNDPYFNQSS--YNASLFENSPSGSPVVQL 520
Score = 88.2 bits (209), Expect = 2e-15
Identities = 134/642 (20%), Positives = 256/642 (39%), Gaps = 61/642 (9%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F + A D D G + Y + +GN+ +F++DS G + K LD + +F
Sbjct: 2087 FVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRET-----TASFD 2141
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L ++ + P K+ +V++ + DLNDN P F+ ++I E+ G V V+ATD
Sbjct: 2142 LVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVTSVVATDT 2200
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
D + TY L K A + + + + D+++ S+ ++K TN +
Sbjct: 2201 D--KESRLTYNL---KSA-----STPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDY 2250
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
D+ R+ ++ + +++ ++ + + ++ + +V + +T
Sbjct: 2251 KIDADTGVISARRTIDVRI---RDSFI---QIPVQAMDQGVPPQRALVYVRIIIT----- 2299
Query: 454 DNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVLYDLQRTSNLTITSPF 511
P F +PS Y + NA +GT + V+ D G G + Y+++ ++ F
Sbjct: 2300 -REPKFELPS--YFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNY------F 2350
Query: 512 KINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
+I +G +SV P+ + R L V A D A PS+ V + V
Sbjct: 2351 RIGQRSGVISV-NKPLDYETKRRFLLVVSAIDDTA-PSK------PVRVPVYINVSDVND 2402
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERS 626
+ P F + Y + +GT V + D+ V + + G ++G FA++ ++
Sbjct: 2403 EKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKG-SFAIDRKT 2461
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
GVI L + A E + + + T+ V+D+ND V P
Sbjct: 2462 GVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVF--RVPGPND 2519
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
V EN +++ N + + F + + G + T D
Sbjct: 2520 VQVLENL--PLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFD 2577
Query: 746 REKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
E VY+ ++ I + G + + + + DE++ P F Y+ + N+KIG
Sbjct: 2578 YENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGD 2637
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
+ + ATD D G + + ++ TG++
Sbjct: 2638 FVGQ---VTATDRDSGDQGRVFFVFYNPTSNALKMNATTGII 2676
Score = 87.8 bits (208), Expect = 2e-15
Identities = 58/172 (33%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL----FSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
++A+DQD G + L Y + + + + F++D +G + DLD E Q V
Sbjct: 411 VNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSG--MITTATDLDRE---QIPQVV 465
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V +P + V + L D NDN P F YN S+ EN P+G V+Q++A D
Sbjct: 466 LTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDP 525
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D GEN Y + P F +DPR G +T N LD E SS +V A +
Sbjct: 526 DIGENSLILYSILTPNTPFFLDPRKGLVT--NSRTLDHEVQSSYTFQVAATD 575
Score = 84.2 bits (199), Expect = 2e-14
Identities = 53/166 (31%), Positives = 86/166 (51%), Gaps = 6/166 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ D D GV + + L+S N LF+LDS G+L L K +D + A ++ L VQ
Sbjct: 829 VSVFDADSGVLGRVSFSLLS-NPGTLFNLDSNTGALSLTKLID----YGNSARSYTLPVQ 883
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P +++ A +E++++D+ND P F Y ++E P ++++V+ATD D GE
Sbjct: 884 AQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGE 943
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG +Y D R+G + ++ LDRE +KV A
Sbjct: 944 NGRISYAFDSKVDTSKFGLRNGG-KIFIKSKLDREDIEEYNLKVIA 988
Score = 83.8 bits (198), Expect = 3e-14
Identities = 94/362 (25%), Positives = 155/362 (42%), Gaps = 36/362 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI----GPSLTIPLTVPRGL 138
VTV + DVND P F Y VTV+E P G + + LIA GP+ I + G
Sbjct: 1105 VTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGS-SLLTLIATDDDQQGPNSDITYMIVAGP 1163
Query: 139 TIFKDIRAFD-------RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
F + D+ T +H +V+ + G+ +LE+ + ++ D
Sbjct: 1164 KAFSLNQVTGVLTLVSPLDREVTHRHILH--VVASDKGGNQSLET-----ITYIEINVLD 1216
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDS 248
D + + K + +++ + A+ D D G +RY++++GN F ++
Sbjct: 1217 VNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINE 1276
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL-KTAQARVEIELLDLNDNLPEFE 307
G + + LD + N +VL+V A+ + KT+ V I + D NDN P F+
Sbjct: 1277 TTGVISTLRALDFEV-----TNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFD 1331
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRN 365
+ I EN+P +V + A D D G N Y +D P+ F I+ +G ++
Sbjct: 1332 KNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETG--LIQT 1389
Query: 366 QTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP---LEKTTYVFP 422
+DRE S +KV A + + ++ + K Q L NAP TYV
Sbjct: 1390 THPIDREEISEYSLKVRATDQAFTEQDRLYNTATL-KIIIQDLNDNAPKFVSRNLTYVME 1448
Query: 423 DK 424
D+
Sbjct: 1449 DE 1450
Score = 81.8 bits (193), Expect = 1e-13
Identities = 86/327 (26%), Positives = 139/327 (42%), Gaps = 22/327 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPS 127
G + Y +VT+ + D+NDN P F + V + E TP G + + +G
Sbjct: 783 GTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRV 842
Query: 128 LTIPLTVPRGL-TIFKDIRAFDRDKP-NTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
L+ P L + + A K + NS Y++ V D G S+ L +
Sbjct: 843 SFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 902
Query: 185 RKVLDYDA--GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
V DY G+ + ++ + I + A D D G + Y S D
Sbjct: 903 VDVNDYSPVFGNWSYTAHVLETTPPDSNII----EVVATDVDSGENGRISYAFDSKVDTS 958
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F L + G +F++ +LD + + L+V A P +++ A V++ + D+NDN
Sbjct: 959 KFGLRN-GGKIFIKSKLDRE-----DIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDN 1012
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P F+ Y + EN P + V A+D D+G NG TY+ D F +D ++G +T
Sbjct: 1013 NPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQTGKIT 1072
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPS 389
VLDREA +S + A + S
Sbjct: 1073 --TSQVLDREAKASYVFSIVATDGGSS 1097
Score = 81.8 bits (193), Expect = 1e-13
Identities = 69/245 (28%), Positives = 110/245 (44%), Gaps = 13/245 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A L Y + SG + FS+D +G + LD + + +T+ L V
Sbjct: 1563 VTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKK-----DTYFLTVH 1617
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ ++ P + + V I ++D NDN P+F + + EN P + + D D G
Sbjct: 1618 ATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARL-IYTLTVQDLDYGN 1676
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
N + Y + + GAF+I +G L+ T LDRE +S ++ V AK+ P FA
Sbjct: 1677 NTKVLYSIMSGNTDGAFTIGRSTGELS--TTTKLDRETKASYQLSVQAKDITPPYYTAFA 1734
Query: 396 D-SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
+ + I P L +T GT N+ D+ S N+ TL +ND
Sbjct: 1735 NITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL--SND 1792
Query: 455 NNPVF 459
V+
Sbjct: 1793 TYGVY 1797
Score = 79.8 bits (188), Expect = 5e-13
Identities = 107/412 (25%), Positives = 156/412 (37%), Gaps = 35/412 (8%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L + E+ P + + ALD D+G G + Y S K S D
Sbjct: 1443 LTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSP---DTGKFSLDL----------- 1488
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ G + + SL E ++ L+ISA D G+ L V V DVND+ P F + +
Sbjct: 1489 KTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIG 1548
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRE 1111
V E + T + KV A D D G NA LTY I PS ++ F I +G++ N LDRE
Sbjct: 1549 TVSENKPTGTSVVKVTAYDRDSGSNAELTYSI-PSGVEMDKFSIDKHSGLIVTNSILDRE 1607
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+D Y LTV A D NDN PKF ++ K PE N
Sbjct: 1608 KKDTYFLTVHA-TGVSYPFRVSSTSVRINVMDRNDNPPKF--ISPVVTLKVPE-----NS 1659
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNLG 1228
+ + V N + ++ + IG G + + + K L
Sbjct: 1660 PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLS 1719
Query: 1229 LPSLSSTAILMVTVADVPDEVE--MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
+ + T A++ +E + PVF Y I E P LNLT +
Sbjct: 1720 VQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISE--LTPPGTSILNLTASDK 1777
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ I+ D + ID R G +Y + +K Y A+ Q
Sbjct: 1778 DSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ 1829
Score = 78.6 bits (185), Expect = 1e-12
Identities = 63/212 (29%), Positives = 97/212 (45%), Gaps = 19/212 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G+ +++L A D D G N I Y L F ++ R G V
Sbjct: 509 ENSPSGSPVVQLLAQDPDIGENSLILYSI---------------LTPNTPFFLDPRKGLV 553
Query: 1002 IVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+R+L E S + ++A DGG + N +V V + D+ND+ PVF + Y+ E
Sbjct: 554 TNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTR 613
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ + ++ A D D + A + I+ + D F + +G++++ LDRET+D Y+LT
Sbjct: 614 IGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLT 672
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V A D G DVND P F
Sbjct: 673 VKAVDGG-GQDSVNKAIVNITVLDVNDEPPIF 703
Score = 71.7 bits (168), Expect = 1e-10
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 15/217 (6%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L +PE+ PIG T ++ D DSG+ G++ + S P + + D+
Sbjct: 813 LVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSN---PGTLFNLDSNTGALSLTKLI 869
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+G+ ARS + L + A DGG+ + + + V DVND+ PVF Y +V
Sbjct: 870 DYGN--SARS------YTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHV 921
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + +V ATD D G+N ++Y F + G + + +LDRE +
Sbjct: 922 LETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRN-GGKIFIKSKLDREDIE 980
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y L V+A D+G DVNDN+P F
Sbjct: 981 EYNLKVIAIDHG-TPRRSSSADVKVIVDDVNDNNPHF 1016
Score = 70.5 bits (165), Expect = 3e-10
Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 7/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HAI +D G A + Y + GN + ++S G+L+L+ E+D + +L L VQ
Sbjct: 725 VHAISRDKGTNAEVVYSISKGNTDNIVLINST-GTLYLQSEVDHEKIPSLY-----LTVQ 778
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P A V I ++D+NDN P+F + + E+ P G + V D D G
Sbjct: 779 AKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGV 838
Query: 338 NGEFTYQ-LDDPKGAFSIDPRSGWLTV 363
G ++ L +P F++D +G L++
Sbjct: 839 LGRVSFSLLSNPGTLFNLDSNTGALSL 865
Score = 68.1 bits (159), Expect = 2e-09
Identities = 81/323 (25%), Positives = 140/323 (43%), Gaps = 31/323 (9%)
Query: 82 SVTVYIEDVNDNVPIFL-DTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT- 139
+V VY++D+NDN P F+ T + V E + I + + G + T T+ G
Sbjct: 43 TVLVYVQDLNDNSPSFVRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVG 102
Query: 140 -IFKDIRAFDRDKP--------------NTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
+FK I D D + D + +S +D G+ A +H + L
Sbjct: 103 NVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPA---NHGFLRLS 159
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGND-RK 242
V D + EF V + + ++ + A D+D+G A ++Y + + +D +
Sbjct: 160 ITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQA 219
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+F + G + LD +A+ + V++ + ++ L ++ A V IE+LD+NDN
Sbjct: 220 IFGIHPTTGVIVNNVRLDYEAKRSY---LIVVKAEDKGSSHQLSSS-AIVRIEVLDVNDN 275
Query: 303 LPEFEVDFY---NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI--DPR 357
P V + + + EN G V +V +D D G+NGE L+ G FS+ D
Sbjct: 276 NPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVL 335
Query: 358 SGWLTVRNQTVLDREAHSSLRMK 380
+ + LDRE H +K
Sbjct: 336 NDESIIAVGQSLDRETHDHFFLK 358
Score = 67.7 bits (158), Expect = 2e-09
Identities = 57/192 (29%), Positives = 93/192 (48%), Gaps = 20/192 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E IP+GT ++ ++A D DSG NG++ + S + K F I+ + G +
Sbjct: 2418 EGIPVGTIVVNVSAADKDSGANGRVWFAIQSG-------------DDKGSFAIDRKTGVI 2464
Query: 1002 IVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN-FNVEE 1056
R+L E+ +++ A D G+ ++ ++SV + V D+ND+ PVF+ N V E
Sbjct: 2465 RTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLE 2524
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED-- 1114
L +++ATD D G NA L++ + F I +G L+ N D E
Sbjct: 2525 NLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVY 2584
Query: 1115 KYILTVVARDNG 1126
+Y LT+ A D G
Sbjct: 2585 QYSLTIKATDAG 2596
Score = 66.1 bits (154), Expect = 7e-09
Identities = 86/322 (26%), Positives = 137/322 (42%), Gaps = 23/322 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTI 130
G +S SV V + D NDN P F + Y+ ++ E +P+G L IG + I
Sbjct: 474 GSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLI 533
Query: 131 PLTVPRGLTIF-----KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
++ T F K + R + S + + + + G + H + L
Sbjct: 534 LYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLN 593
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
+ D V RI + I + AID+D A R+ + GN ++FS
Sbjct: 594 D--NQPVFDPSSYSVEYFENTRIGQSIC---QLKAIDRDSPKFAITRFIIEQGNADEVFS 648
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+D +G + L K LD + + N ++L V+A +A V I +LD+ND P
Sbjct: 649 VDG-SGLITLAKLLDRETQDN-----YLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPI 702
Query: 306 FEVDFYNISIVENLPNGFSVL-QVMATDKDQGENGEFTYQLDDPKG-AFSIDPRSGWLTV 363
F YN +I E+ SV+ V A +D+G N E Y + KG +I + T+
Sbjct: 703 FSKAEYNFTIQEH-SQALSVIGHVHAISRDKGTNAEVVYSIS--KGNTDNIVLINSTGTL 759
Query: 364 RNQTVLDREAHSSLRMKVYAKE 385
Q+ +D E SL + V AK+
Sbjct: 760 YLQSEVDHEKIPSLYLTVQAKD 781
Score = 62.9 bits (146), Expect = 7e-08
Identities = 45/156 (28%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y F +D G + + LD +A+ + +V +
Sbjct: 1038 VSASDSDEGSNGHVTYRF--DTQVAQFIVDKQTGKITTSQVLDREAKAS-----YVFSIV 1090
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
A+ + + + +V + + D+ND P+F + Y++++ E+LP G S+L ++ATD D QG
Sbjct: 1091 ATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQG 1150
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
N + TY + AFS++ +G LT+ + LDRE
Sbjct: 1151 PNSDITYMIVAGPKAFSLNQVTGVLTL--VSPLDRE 1184
Score = 58.0 bits (134), Expect = 2e-06
Identities = 71/249 (28%), Positives = 103/249 (41%), Gaps = 20/249 (8%)
Query: 990 RYFVINERHGHVIVARS--LPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFP 1043
R F ++ G + VA + L ES FRL++ A G +LN + + + V D ND+ P
Sbjct: 2006 RAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSP 2065
Query: 1044 VFKKTWYNFNVEE--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
F + + E + R + KV ATD D G N +TY I + F I TG
Sbjct: 2066 AFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGE 2125
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
++ LDRET + L + D+G D+NDN P FD L E
Sbjct: 2126 ITTAKLLDRETTASFDLVIRGTDSG-IPPKSTNCQVKVVVTDLNDNPP---LFDPLSEVN 2181
Query: 1162 HPEADELSNHNFESVMMIPVYKAT-----IEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
E D + SV+ K + ++ + G + +V A D D N I Y
Sbjct: 2182 IRE-DTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQD--SGSNAQIKY 2238
Query: 1217 SLPQRKNQQ 1225
S P + Q
Sbjct: 2239 SFPITNSDQ 2247
Score = 57.6 bits (133), Expect = 2e-06
Identities = 73/314 (23%), Positives = 119/314 (37%), Gaps = 30/314 (9%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT 139
+L +++ +ED NDN P F + Y T+ E G I ++ + + +
Sbjct: 155 FLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTS--ILQVSASDKDIGTNAEIQYSIE 212
Query: 140 IFKDIRAFDRDKPNTP----NSDVHYS-------IVSGNDDGHFALESSHKPVLLLRKVL 188
D +A P T N + Y +V D G SS V + +VL
Sbjct: 213 THSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRI--EVL 270
Query: 189 DYDAGDKEFQLVIMASGK-RIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLF 244
D + + + G ++ + + + D D G + L G+
Sbjct: 271 DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSM 330
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
D +N + LD E + + F L+ +P +T + I + D+ND P
Sbjct: 331 KFDVLNDESIIAVGQSLDRETH---DHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAP 387
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA------FSIDPRS 358
+F+ Y + EN V V A D+D G N E Y + + + F+IDP S
Sbjct: 388 KFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSS 447
Query: 359 GWLTVRNQTVLDRE 372
G +T T LDRE
Sbjct: 448 GMIT--TATDLDRE 459
Score = 54.0 bits (124), Expect = 3e-05
Identities = 48/188 (25%), Positives = 89/188 (47%), Gaps = 28/188 (14%)
Query: 929 LDVDQLGPLFLIP--------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
LD++ P+F +P EN+P+ + + ++NA D DSG N ++ +
Sbjct: 2503 LDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGG------- 2555
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPES----EFRLNISALDGGN--LNDNISVRVF 1034
+ L F+I++ G + + E+ ++ L I A D GN L+ NI++ V
Sbjct: 2556 -TGQGL-----FLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVN 2609
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V D +++ P F + Y F+V +G+V ATD D G + +F+ + T +
Sbjct: 2610 VADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRV-FFVFYNPTSNALK 2668
Query: 1095 ISPLTGVL 1102
++ TG++
Sbjct: 2669 MNATTGII 2676
Score = 52.8 bits (121), Expect = 7e-05
Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D G + Y L S + ++S+DS G ++ + + + N F +
Sbjct: 1774 ASDKDSGSNGNIVYTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQ--EYNFFCIAKDQG 1830
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT--DKDQGE 337
Q +P K A V I++ D N++ P+F Y + I N V V AT D D+
Sbjct: 1831 Q--DP-KMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKST 1887
Query: 338 NGEFTYQLDDPKGAFSI 354
NG+ TY+LDD K + S+
Sbjct: 1888 NGKVTYRLDDSKNSTSL 1904
>UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Fat4 - Strongylocentrotus purpuratus
Length = 4811
Score = 149 bits (361), Expect = 6e-34
Identities = 133/469 (28%), Positives = 202/469 (43%), Gaps = 35/469 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S +++ LLD NDN+PVF S Y F + + VG +G V A DPD G NG V
Sbjct: 1658 DGTLTSTTTIDINLLDENDNDPVFSLST-YSFLVPEDEMVGEDVGVVVATDPDAGLNGEV 1716
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLA 553
Y + F ++P TG + +S E + F V A+D+ ++P R S A
Sbjct: 1717 AYSVVE-EGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMATDKGSSP---RSSTA 1772
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLL 611
V I V N P + Y V +V IGTSV + D+ ++ + +
Sbjct: 1773 TVYINVEDVNDNN----PVYNPVDYSEEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIA 1828
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA----LQENANLSIVTNATVHVV 667
G + F V +G I + +L R Y+ E VA L S ++ V
Sbjct: 1829 SG-DPSQRFTVYP-NGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRSSTAQVSIIVT 1886
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
D+ND +P + E++ I + + N L
Sbjct: 1887 DINDNAPRFT----NPDSVEIAEDTRTNVIIMVLRAEDDDVERNSYVEYYLLTPGVPFAV 1942
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ +G + PLDRE Y + V A +KG + +TIYI D NDN P F
Sbjct: 1943 SRV----EGNMQVTGPLDRETESSYALLVQAT-DKGTPPQSSTMNLTIYITDVNDNAPAF 1997
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVV 846
YE + E++ +G E + A+D DEG N++ Y++F G+ F +D TGV+
Sbjct: 1998 SMTPYEATLDEDTPVGLEFLK---VTASDPDEGLNSIIRYSIFSGDSGRAFAIDPVTGVL 2054
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEF 893
+ L+ E++ Y L++ A+D G + S + I + D NDN P F
Sbjct: 2055 S-VNSGLNYEQRSSYTLTVRAQDQGYSTQVSSVTVTITVADVNDNAPVF 2102
Score = 134 bits (323), Expect = 2e-29
Identities = 170/687 (24%), Positives = 289/687 (42%), Gaps = 57/687 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + + D NDNNPV+ P + Y + + +GT + + A D D G NG + + +
Sbjct: 1770 STATVYINVEDVNDNNPVYNPVD-YSEEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIA 1828
Query: 501 RTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ F + PN V++ E + L V ASD +P +RR S A V+I V
Sbjct: 1829 SGDP---SQRFTVYPNGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRSSTAQVSIIV 1885
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV-NDAFEQND-VSYDLLHGYEEG 617
T N P + P + + + +R +D E+N V Y LL G
Sbjct: 1886 T-DINDNAPRFTN----PDSVEIAEDTRTNVIIMVLRAEDDDVERNSYVEYYLL---TPG 1937
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
VPFAV G + V L R Y A + S N T+++ DVND
Sbjct: 1938 VPFAVSRVEGNMQVTGPLDRETESSYALLVQATDKGTPPQSSTMNLTIYITDVNDNAPAF 1997
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV-RFLIANQQDVTDDIAIAED 735
+ +P + E++ +G F +S G ++ R+ I +
Sbjct: 1998 ---SMTPYEATLDEDTP---VGLEFLKVTASDPDEGLNSIIRYSIFSGDSGRAFAIDPVT 2051
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + L+ E+R Y +TV A+ ++G + VTI + D NDN PVFE + Y
Sbjct: 2052 GVLSVNSGLNYEQRSSYTLTVRAQ-DQGYSTQVSSVTVTITVADVNDNAPVFEDS-YAPS 2109
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
IMEN+ +I ++A DAD G N + + L + +F + +G+++ + + LD
Sbjct: 2110 IMENNLPNADIVQ---VRADDADSGVNGMINFRLESDYNGLFTIGSTSGLIQ-VTEVLDY 2165
Query: 856 EKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG- 912
E + ++L ++A D+G S + + + + D+ND+ PEF + + + + + +
Sbjct: 2166 EDQNEFELIVIAEDSGTPSHQTRTTMTLTVNDDNDHDPEF--VSDFYRATVSEDASADTF 2223
Query: 913 --TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
T ++ ++ L+ D +G F I P+G I+ LD + Q Y
Sbjct: 2224 VIQVTATDVDATAALRYRLNSD-IGSKFTID---PLGGRILTTGLLDREV----QSSYLL 2275
Query: 971 NSEVYIPPSKLSADALEVKRYFVINE--RHGHVIVARSLPPESEFRLNISALDG--GNLN 1026
V PS+L+ ++ V+ V + R +LP S+ ++A+ +L
Sbjct: 2276 TVTVDDGPSRLATTSVRVEVLDVNDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLE 2335
Query: 1027 DNISVRVFV------KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
DN ++R + K V D T F E + Y ++ + A+ + +
Sbjct: 2336 DNAAIRYSITSGDTSKFVVDQDTGVVITAQGFTDENSPYDLQITAENVASGQNSAVASLR 2395
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGE 1107
F S D+ F P +G S GE
Sbjct: 2396 VIFSTASFPDITF---PFSGTSSSYGE 2419
Score = 125 bits (302), Expect = 8e-27
Identities = 160/655 (24%), Positives = 270/655 (41%), Gaps = 64/655 (9%)
Query: 441 SFVNVEVTLLDANDNNPVF---VPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+FVNV V D ND++PV +P + S + + +KA+D D +NG V
Sbjct: 179 AFVNVMVE--DENDHSPVIEVLIPEIEASGVASISETMLPGPLFNLKAIDEDREENGRVS 236
Query: 497 YDLQRTSNLTITSPFKINPNTGTVS--VAESPILEGRHALFVE-----ASDQPANPSERR 549
+ ++ S I+ TG V + SP + A++ P R
Sbjct: 237 MSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDREIIASYNLTFAAEDMGTPPRRT 296
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
Y ++ + P F+ Y + ++ +G+ V + DA E D+
Sbjct: 297 YRSIIIYVV------DENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIV 350
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHV 666
Y + G E G F ++ +G++T + L A + ++ T T+ +
Sbjct: 351 YSIT-GDEYGW-FQIDNGTGLVTTREKLDHETAAQVTLTITASDQGLEPMANTTILTIDI 408
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQD 725
DVNDE V + A+S V+ENS + Q+ T++ NG G+V + ++ Q
Sbjct: 409 QDVNDEYPVFNQIAYSET---VEENSPARDLIQVLATDLD----NGVNGDVTYTFSSDQY 461
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
E G + PLDRE++D Y + ++A + G S VTI + D+NDNPP
Sbjct: 462 SGMFSLDPESGLLQITVPLDREEQDSYELEILAS-DGGSPSLQATATVTIAVLDQNDNPP 520
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
F Y ++EN G + ++ ATD D G N +++L K F +D +G
Sbjct: 521 QFYPTEYYASVIENGPAGLFV---TVVSATDLDVGVNGAVIFSLSDSSK--FQIDSYSGN 575
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN------QIE 897
V +SLDRE++ Y L++ A+D G + A + + + D DN EF Q+E
Sbjct: 576 VT-TRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNPYRFQLE 634
Query: 898 ENSKVRIHRET------KLNGTAGFTIIEVKPKNKFALD-VDQLGPLFLIPENIPIGTTI 950
EN R T LN + I+ P F +D + L + +
Sbjct: 635 ENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYSGVIKTTLSIDREAHESAS 694
Query: 951 IKLNALDLDSGLNGQIRYE---FNSEVYIPPSKLSADALE-VKRYFVINERHGHVIVARS 1006
+L L +D NGQ E + P L D ++ V+ + V N+ + +
Sbjct: 695 FRLTVLAVDGSQNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYAAQVTDAD 754
Query: 1007 LPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
PP + + L+++ D +N V KD+ + + + YN ++ Y
Sbjct: 755 SPPNNVILYDLSVNFDDRFGINHTSGVLFLNKDLQN----YPEKEYNLQIQATDY 805
Score = 119 bits (286), Expect = 7e-25
Identities = 195/836 (23%), Positives = 334/836 (39%), Gaps = 95/836 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V V +ED ND+ P+ V + E+ +G + + P GP +F
Sbjct: 181 VNVMVEDENDHSPVI-----EVLIPEIEASGVASISETMLP-GP-------------LF- 220
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIM 202
+++A D D+ N V SI SGND F+ S P GD F L +
Sbjct: 221 NLKAIDEDREE--NGRVSMSIHSGNDRNDFSGTSISLPT-----------GDVFFLLRVS 267
Query: 203 ASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD-SVNGSLFLEKELDL 261
S I +EI+ + +D+G Y I ++ +D + + +FL++
Sbjct: 268 PSAN-IDREIIASYNLTFAAEDMGTPPRRTYRSII-----IYVVDENDHAPMFLQESYRA 321
Query: 262 DAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN--ISIVENL 319
++Q +FV V A+ + + +I D F++D ++ E L
Sbjct: 322 GLLESIQVGSFVKSVTATDADEGINA-----DIVYSITGDEYGWFQIDNGTGLVTTREKL 376
Query: 320 PNGFSV-LQVMATDKDQG-----ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREA 373
+ + + + T DQG T + D + + + + + R+
Sbjct: 377 DHETAAQVTLTITASDQGLEPMANTTILTIDIQDVNDEYPVFNQIAYSETVEENSPARDL 436
Query: 374 HSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQP----LETNAPLEKTTYVFPDKVGTKT 429
L + N V TF+ Q + P L+ PL++ D +
Sbjct: 437 IQVLATDL-DNGVNGDVTYTFSSDQYSGMFSLDPESGLLQITVPLDREEQ---DSYELEI 492
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
+ L + V + +LD NDN P F P+ Y S+ N G + V A D D+
Sbjct: 493 LASDGGSPSLQATATVTIAVLDQNDNPPQFYPTEYYA-SVIENGPAGLFVTVVSATDLDV 551
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR 549
G NG V++ +L+ +S F+I+ +G V+ ES E + + + Q +
Sbjct: 552 GVNGAVIF------SLSDSSKFQIDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAA 605
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
S A + + VT T N +F PY F + N T VG + +++Y
Sbjct: 606 QS-ATIFVTVT-DTLDNP---LEFELNPYRFQLEENRPNRTEVGTVLATSMDLNVEITYV 660
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
+++G G+ F ++ SGVI + R F L + + + T + ++D+
Sbjct: 661 IVNGDPNGL-FVIDFYSGVIKTTLSIDREAHESASFRLTVLAVDGSQNGQTVVEIEILDI 719
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND V A V EN A+G F+ + + NV L + D
Sbjct: 720 NDNAPVF---ALPEDQVDVVEN---WAVGNKFYAAQVTDADSPPNNV-ILYDLSVNFDDR 772
Query: 730 IAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I G +F K L Y + + A + G + + + + D N+N PVF
Sbjct: 773 FGINHTSGVLFLNKDLQNYPEKEYNLQIQAT-DYGTPPLSSSMNLLVTVRDVNNNAPVFV 831
Query: 789 HATYEGFIMENSKIGTEIKMDNII---KATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
+ I ++ I +++I+ ATDAD+GTN L Y + + F + + G+
Sbjct: 832 DS-----INTTLRLTESIPVNSIVIHALATDADQGTNGLISYRITSGNTDSFGIFPD-GM 885
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEEN 899
V ++ +LDRE+ Y L++ A D G ++S L I++ DENDN+P F+ N
Sbjct: 886 V-YVKRALDREQVDQYDLTIEATDGGVPSMTSTLMLEIIVLDENDNRPFFDNATYN 940
Score = 118 bits (284), Expect = 1e-24
Identities = 127/480 (26%), Positives = 219/480 (45%), Gaps = 52/480 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V+V + + D NDN P F S ++A T + V A DPD G NG V Y L T
Sbjct: 1350 VDVVIFVRDINDNAPRFTSQQAAAISRSTSAN--TRVTTVHADDPDTGVNGQVTYTLIST 1407
Query: 503 SNLTITSPFKINPNTGTVSVAES-PILEGRHALFVEASDQPANPSERR--YSLAVVTIEV 559
PF+++ TG +++ + P ++L + A D +NP ++ +SLA++ +
Sbjct: 1408 G-----VPFRLDLITGELTLTQPIPSSANIYSLDIRADDAGSNPQQQSTPFSLAIIISD- 1461
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVND---AFEQNDVSYDLLHGY 614
+ I +++ Y V N GT + + + +D A + VS G
Sbjct: 1462 ------GQSSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGV 1515
Query: 615 EEGVPFAVEERSGVI---TVVD--DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
++G +G+I V+D DL + + AV +++ TV+V+D
Sbjct: 1516 DKGSLIRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDE 1575
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTD 728
ND V G P ++EN A ++ + ++ + + D TD
Sbjct: 1576 NDNAPVFTNG---PYTASIRENVAS-------NSPVKTVMATDADLDTIIFYSIVDGATD 1625
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+I + G I T+ +DRE VY++ + A + G ++ + + DENDN PVF
Sbjct: 1626 LFSIDSTTGQIRTRGVVDRESSAVYQLQLQA--SDGTLTSTTTIDINLL--DENDNDPVF 1681
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GKEMFDVDENTG 844
+TY + E+ +G ++ ++ ATD D G N Y++ E G+++F +D TG
Sbjct: 1682 SLSTYSFLVPEDEMVGEDV---GVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATG 1738
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ + SLD E K Y ++++A D G SS A + I + D NDN P +N ++ + +V
Sbjct: 1739 AFR-LQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEV 1797
Score = 118 bits (283), Expect = 2e-24
Identities = 132/496 (26%), Positives = 218/496 (43%), Gaps = 41/496 (8%)
Query: 414 LEKTTYVFPDK-VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN 472
L K +P+K + + +Y L S +N+ VT+ D N+N PVFV S + +
Sbjct: 784 LNKDLQNYPEKEYNLQIQATDYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTES 843
Query: 473 AKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--G 530
V +++ A D D G NG++ Y + TS T F I P+ G V V + E
Sbjct: 844 IPVNSIVIHALATDADQGTNGLISYRI--TSG--NTDSFGIFPD-GMVYVKRALDREQVD 898
Query: 531 RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGT 590
++ L +EA+D L ++ ++ + P F A Y F++ IG
Sbjct: 899 QYDLTIEATDGGVPSMTSTLMLEIIVLD-------ENDNRPFFDNATYNFYLSEEDDIGA 951
Query: 591 SVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN-----RPMY 643
+VG I ND +++Y + F + +G IT L R + +P
Sbjct: 952 AVGTIHAVDNDVGGNGELTYSFTANH---TLFTLNSVTGAITSKVSLDRESLVEAGQPTT 1008
Query: 644 DFEAVALQENANLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF 701
V + ++ + +A +HVVD+ND V + ++ + + +N I ++
Sbjct: 1009 FSIRVRVHDSGQPQLQDHADVNIHVVDINDSPPVFNRESYQASVSELAQNE--TLIIRVS 1066
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN 761
T+ G+ + + +++ ++ I G I PLDRE + Y + V A +
Sbjct: 1067 ATD--DDVGDNSYILYSIVSGNEEKRFHIDHVH-GQIVLIAPLDREVTEGYVLRVKAR-D 1122
Query: 762 KGVISGAGIYQVTIYIEDENDNPPVFE-HATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
G++ +V I + DEND+ P F E + E +IG I ++ATD D
Sbjct: 1123 GGIVPQESFVEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDTI---GGVQATDMDIN 1179
Query: 821 TNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA-- 877
+N YT+ G + +F V+ N+G V G LD E Y L++ ARD G S +A
Sbjct: 1180 SNGQISYTITGGNLDGVFGVNANSGEVYLTG-YLDHEATSQYSLNITARDGGSPSLQAVV 1238
Query: 878 ELIIMIGDENDNKPEF 893
++I I D NDN P F
Sbjct: 1239 SMVINIRDCNDNSPIF 1254
Score = 116 bits (279), Expect = 5e-24
Identities = 177/703 (25%), Positives = 287/703 (40%), Gaps = 94/703 (13%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL FV ++V++LD NDN P+F S +Y S+ + V A D D NG V Y
Sbjct: 2485 QLSDFVELQVSVLDVNDNAPLFDQS-VYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSY 2543
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVV 555
+ + + F I+ ++G ++ + E + L VEA+D NPS+ ++ VV
Sbjct: 2544 AITLGNT---NNAFDIS-SSGVITTTQPLDRETVASYILTVEATDG-GNPSQSGSAIVVV 2598
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
T+ N+ Y+ + + GT V + D E N + + G +
Sbjct: 2599 TVT---DINDNRMSFTKM----YDATIPEDAPPGTHVVTLHTTDPDENNLSQFSIEAGGQ 2651
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ FA+ +G IT+ L + ++ + +++ + T V+V D ND V
Sbjct: 2652 SSL-FAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDSSHEVQTQVLVNVEDTNDNAPV 2710
Query: 676 LLKGAHS---PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + + P IF S+G I + T+ G V +++ + I
Sbjct: 2711 FTENSINTTYPEIFF----SSGNVIATVSATDADD---GDNGQVDYILKTMTEHFRVETI 2763
Query: 733 AEDGTIFTQKPL--------DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
G IF P+ D + Y +V A ++G + G V I + +N
Sbjct: 2764 NNRGWIFPVPPISYIVPSPEDTSNPNTYTFSVFA-VDRGTPALYGEASVIITVTQDNSYT 2822
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
PVF +Y + N++ T + + A D D G+NA Y+ + + G
Sbjct: 2823 PVFATPSYFSPVTANTRSNTRVLQ---VLAVDQDTGSNAAITYS----------ISDGNG 2869
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
KF V DTG + ++ + + GD + +N ++
Sbjct: 2870 TEKFD----------------VEADTGWILTKG--VSLAGDVGITYQLLVKATDNGNIKK 2911
Query: 905 HRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
ET T F I + N D D I E++ G + + A D DSG+NG
Sbjct: 2912 EDET----TVTFLITDSND-NAPVFDDDTYRSS--IAEDV--GGYVATVRAEDDDSGING 2962
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDG 1022
+I Y + ADA F I+ G V + SL E+ E ++ ++A D
Sbjct: 2963 EITYSISG----------ADAA----LFSIDAVSGIVSLVGSLDRETSDEHQIQVTAEDR 3008
Query: 1023 GNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
+ + + + V V DV+D+ PVF Y +V E + + V ATDAD G NA+
Sbjct: 3009 AMYSQSATAILIVTVTDVDDNPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADF 3068
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRET-EDKYILTVVA 1122
Y I D F I+P TG++ G LD ET + Y LTV A
Sbjct: 3069 EYIISGGDGTDFFTINPETGLILTQGNLDYETGKTTYHLTVAA 3111
Score = 112 bits (270), Expect = 6e-23
Identities = 121/465 (26%), Positives = 206/465 (44%), Gaps = 36/465 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ +V V +LD NDN P F P++ Y ++ + ++ G + ++A D DL N + Y +
Sbjct: 2286 LATTSVRVEVLDVNDNPPRFSPTS-YTATLPATSQQGCFVAAIQATDTDLEDNAAIRYSI 2344
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTIE 558
TS TS F ++ +TG V A+ E + L + A + + + AV ++
Sbjct: 2345 --TSG--DTSKFVVDQDTGVVITAQGFTDENSPYDLQITAENVASGQNS-----AVASLR 2395
Query: 559 VTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
V T + PDI F G + G NV G +V + V+Y + G G
Sbjct: 2396 VIFST-ASFPDITFPFSGTSSSY--GENVMTGMTVTTVTAIGI-----VTYSIAGG-NHG 2446
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVL 676
F V +SG ++++ +L + A N LS V V+DVND +
Sbjct: 2447 EHFGVGSQSGEVSIIKELDYEESKSFSLWIAATDTANTQLSDFVELQVSVLDVNDNAPLF 2506
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + + V+E S + + T+ S+ NG + + N + D I+ G
Sbjct: 2507 DQSVYFTSV--VEEQSGQVQVVSVSATDEDSL-SNGDVSYAITLGNTNNAFD---ISSSG 2560
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T +PLDRE Y +TV A + G S +G V + + D NDN F Y+ I
Sbjct: 2561 VITTTQPLDRETVASYILTVEAT-DGGNPSQSGSAIVVVTVTDINDNRMSFT-KMYDATI 2618
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E++ GT + + TD DE + F G+ +F ++ TG + + SLD E
Sbjct: 2619 PEDAPPGTHVV---TLHTTDPDENNLSQFSIEAGGQ-SSLFAINPITGEIT-LNSSLDFE 2673
Query: 857 KKIMYKLSLVARDTGGLSS-EAELIIMIGDENDNKPEFNQIEENS 900
+ ++ L + + D + ++++ + D NDN P F + N+
Sbjct: 2674 DEAVHYLLVKSFDPDSSHEVQTQVLVNVEDTNDNAPVFTENSINT 2718
Score = 111 bits (267), Expect = 1e-22
Identities = 121/466 (25%), Positives = 189/466 (40%), Gaps = 27/466 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V++ + + D NDN+P+F + E + G + +V A D D G NG V +
Sbjct: 1234 LQAVVSMVINIRDCNDNSPIFAYVGVPEIDEEKPE--GFEVVRVSASDSDSGVNGEVRFS 1291
Query: 499 LQRTSNLTITSPFKINPNTGTVSV-----AESPILEGRHALFVEASDQPANPSERRYSLA 553
+ +S F I+P +G ++ ES I+ + A P E R +
Sbjct: 1292 I--SSQRPSGDFFAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTAT 1349
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V + R N P A +N + T D V+Y L+
Sbjct: 1350 VDVVIFVRDINDNAPRFTSQQAAAISRSTSANTRVTTVHADDP--DTGVNGQVTYTLI-- 1405
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
GVPF ++ +G +T+ + + +Y + A +N + + ++D +
Sbjct: 1406 -STGVPFRLDLITGELTLTQPIPS-SANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQ 1463
Query: 674 GVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-A 731
+L + V+EN AG I + V + A D I A
Sbjct: 1464 SSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGVDKGSLIRA 1523
Query: 732 IAEDGTIFTQKPLDREKR---DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+G I T LDRE TV A S QVT+ + DENDN PVF
Sbjct: 1524 SVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFT 1583
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y I EN + +K + ATDAD T + Y++ ++F +D TG ++
Sbjct: 1584 NGPYTASIRENVASNSPVK---TVMATDADLDT--IIFYSIVDGATDLFSIDSTTGQIRT 1638
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
G +DRE +Y+L L A D G L+S + I + DENDN P F+
Sbjct: 1639 RG-VVDRESSAVYQLQLQASD-GTLTSTTTIDINLLDENDNDPVFS 1682
Score = 110 bits (265), Expect = 2e-22
Identities = 113/465 (24%), Positives = 200/465 (43%), Gaps = 36/465 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+++ S V + + D NDN P F + E + + + +I ++A D D+ +N V
Sbjct: 1872 EDRRSSTAQVSIIVTDINDNAPRFTNPDSVEIA--EDTRTNVIIMVLRAEDDDVERNSYV 1929
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSL 552
Y L LT PF ++ G + V P+ E +AL V+A+D+ P +L
Sbjct: 1930 EYYL-----LTPGVPFAVSRVEGNMQVT-GPLDRETESSYALLVQATDKGTPPQSSTMNL 1983
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
+ +V + P F PYE + + +G ++ +D E + + Y +
Sbjct: 1984 TIYITDV-------NDNAPAFSMTPYEATLDEDTPVGLEFLKVTASDPDEGLNSIIRYSI 2036
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDV 669
G + G FA++ +GV++V L+ R Y A + + + + T+ V DV
Sbjct: 2037 FSG-DSGRAFAIDPVTGVLSVNSGLNYEQRSSYTLTVRAQDQGYSTQVSSVTVTITVADV 2095
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND V + +++P I ++ N A I Q+ + S G + F + + +
Sbjct: 2096 NDNAPV-FEDSYAPSI--MENNLPNADIVQVRADDADS---GVNGMINFRLESDYNGLFT 2149
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I + G I + LD E ++ + + VIAE + G S +T+ + D+ND+ P F
Sbjct: 2150 IG-STSGLIQVTEVLDYEDQNEFELIVIAE-DSGTPSHQTRTTMTLTVNDDNDHDPEFVS 2207
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
Y + E++ T +I+ T D A Y L + F +D G +
Sbjct: 2208 DFYRATVSEDASADT-----FVIQVTATDVDATAALRYRLNSDIGSKFTIDPLGGRILTT 2262
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
G LDRE + Y L++ D + + + + D NDN P F+
Sbjct: 2263 G-LLDREVQSSYLLTVTVDDGPSRLATTSVRVEVLDVNDNPPRFS 2306
Score = 109 bits (262), Expect = 6e-22
Identities = 98/357 (27%), Positives = 161/357 (45%), Gaps = 28/357 (7%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F ++ G++ V L E+E + L + A D G + +++ +++ DVND+ P F
Sbjct: 1940 FAVSRVEGNMQVTGPLDRETESSYALLVQATDKGTPPQSSTMNLTIYITDVNDNAPAFSM 1999
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
T Y ++E KV A+D D G N+ + Y I D+ F I P+TGVLSVN
Sbjct: 2000 TPYEATLDEDTPVGLEFLKVTASDPDEGLNSIIRYSIFSGDSGRAFAIDPVTGVLSVNSG 2059
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKHPE 1164
L+ E Y LTV A+D G DVNDN+P F YA ++E P
Sbjct: 2060 LNYEQRSSYTLTVRAQDQG-YSTQVSSVTVTITVADVNDNAPVFEDSYA-PSIMENNLPN 2117
Query: 1165 AD--ELSNHNFES-VMMIPVYKATIEENA--PIGTTVAKVFANDTDFIGNGNGLILYSLP 1219
AD ++ + +S V + ++ + N IG+T + + + N L +
Sbjct: 2118 ADIVQVRADDADSGVNGMINFRLESDYNGLFTIGSTSGLIQVTEVLDYEDQNEFELIVI- 2176
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
++ G PS + + +TV D D P F+S +Y + E+ +A ++ +
Sbjct: 2177 ----AEDSGTPSHQTRTTMTLTVNDDNDH-----DPEFVSDFYRATVSEDASADTFVIQV 2227
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
T+ +RY + ++DI F IDP G + DREV+ +Y + V +
Sbjct: 2228 TATDVDATAALRYRL----NSDIGSKFTIDPLGGRILTTGLLDREVQSSYLLTVTVD 2280
Score = 107 bits (256), Expect = 3e-21
Identities = 114/462 (24%), Positives = 196/462 (42%), Gaps = 36/462 (7%)
Query: 463 NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS--NLTITSPFKINPNTGTV 520
N Y S++ N GT I V A D G++ V Y + + + S + + G +
Sbjct: 1472 NTYTGSVRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGVDKGSLIRASVTNGII 1530
Query: 521 ---SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAP 577
+V + L G +L + S S V +++VT + P F P
Sbjct: 1531 RTDAVLDREDLGGGSSLVATVYAVDTSSS----SSHVTSVQVTVNVLDENDNAPVFTNGP 1586
Query: 578 YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSR 637
Y + NV + V + DA + Y ++ G + F+++ +G I + R
Sbjct: 1587 YTASIRENVASNSPVKTVMATDADLDTIIFYSIVDGATD--LFSIDSTTGQIRTRGVVDR 1644
Query: 638 YNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAI 697
+ +Y + A + L+ T ++++D ND V +S ++ ++ G +
Sbjct: 1645 ESSAVYQLQLQA--SDGTLTSTTTIDINLLDENDNDPVFSLSTYSFLV--PEDEMVGEDV 1700
Query: 698 GQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED--GTIFTQKPLDREKRDVYRMT 755
G + T+ + G V + + + +D+ + G Q+ LD E + Y MT
Sbjct: 1701 GVVVATDPDA---GLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMT 1757
Query: 756 VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
V+A +KG + V I +ED NDN PV+ Y + E+ IGT + + AT
Sbjct: 1758 VMAT-DKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDVAIGTSVV---TLTAT 1813
Query: 816 DADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----- 869
D D G+N +++ G+ + F V N +V +LDRE + Y L +VA D
Sbjct: 1814 DLDSGSNGELQFSIASGDPSQRFTVYPNGTIVTI--KNLDREPESFYNLEVVASDMTLDP 1871
Query: 870 TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
SS A++ I++ D NDN P F + V I +T+ N
Sbjct: 1872 EDRRSSTAQVSIIVTDINDNAPRFTNPD---SVEIAEDTRTN 1910
Score = 105 bits (252), Expect = 9e-21
Identities = 123/485 (25%), Positives = 213/485 (43%), Gaps = 41/485 (8%)
Query: 445 VEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
VE+ +LD NDN PVF +P + + + N VG + D D N ++LYDL
Sbjct: 712 VEIEILDINDNAPVFALPED--QVDVVENWAVGNKFYAAQVTDADSPPNNVILYDL---- 765
Query: 504 NLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
++ F IN +G + + + E + L ++A+D P +L +VT+ R
Sbjct: 766 SVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQATDYGTPPLSSSMNL-LVTV---R 821
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
N P D + + ++ + + V DA + + +SY + G +
Sbjct: 822 DVNNNAPVFVDSINTTLR--LTESIPVNSIVIHALATDADQGTNGLISYRITSGNTDS-- 877
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
F + G++ V L R YD A +++ + V+D ND R
Sbjct: 878 FGIFP-DGMVYVKRALDREQVDQYDLTIEATDGGVPSMTSTLMLEIIVLDENDNRPFFDN 936
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
++ + +E+ GAA+G I H + + GNG F + + + G I
Sbjct: 937 ATYN--FYLSEEDDIGAAVGTI-HAVDNDVGGNGELTYSFTANHTLFTLNSVT----GAI 989
Query: 739 FTQKPLDREKR-DVYRMTVIAEFNKGVISGAGIYQ----VTIYIEDENDNPPVFEHATYE 793
++ LDRE + + T + + SG Q V I++ D ND+PPVF +Y+
Sbjct: 990 TSKVSLDRESLVEAGQPTTFSIRVRVHDSGQPQLQDHADVNIHVVDINDSPPVFNRESYQ 1049
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDS 852
+ E ++ T I + ATD D G N+ +Y++ G ++ F +D G + I
Sbjct: 1050 ASVSELAQNETLIIR---VSATDDDVGDNSYILYSIVSGNEEKRFHIDHVHGQIVLIAP- 1105
Query: 853 LDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LDRE Y L + ARD G + E+ E+ I + DEND++P F+ ++ ++ + ++
Sbjct: 1106 LDREVTEGYVLRVKARDGGIVPQESFVEVEITVLDENDHRPSFS-VDLQREIEVTECLQI 1164
Query: 911 NGTAG 915
T G
Sbjct: 1165 GDTIG 1169
Score = 103 bits (248), Expect = 3e-20
Identities = 128/467 (27%), Positives = 193/467 (41%), Gaps = 46/467 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
VT+ D +DN PVF+P Y + N+ T + V A D D G N Y +
Sbjct: 3021 VTVTDVDDNPPVFLPRE-YRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDG-- 3077
Query: 507 ITSPFKINPNTGTVSVAESPILE-GR--HALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
T F INP TG + + E G+ + L V A+++ A + Y+ +VT+
Sbjct: 3078 -TDFFTINPETGLILTQGNLDYETGKTTYHLTVAATNEQATMVD--YAHVIVTL------ 3128
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFA 621
G P F Y+F+V + G VG + D +D V+Y L G F
Sbjct: 3129 LGENEFYPQFTQHQYDFYVNEHATDGAPVGVVLATDDDLGDDGIVNY-LFIGGSNLQGFN 3187
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH----VVDVNDERGVLL 677
V SG ITV + R +R D +++ N +T A + ++ VND +
Sbjct: 3188 VNLESGQITVAYENGRLDRETADTVLLSVLAK-NEGPITGADIDEAEVIIHVNDGNDAPV 3246
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ ++ G+ + + + I N L N+ D A G
Sbjct: 3247 FSSEQYQARVLESEPPGSDVTVVTAADYDEIPSFRQFNYSILRGNEGDAFH--IDARTGR 3304
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T LDRE VY +TV A + G G V++ ++D NDN PVF EG +
Sbjct: 3305 ITTASLLDRETLSVYFLTVAA-IDTGNPPQTGTAVVSVELDDVNDNGPVFIGEAAEGSVF 3363
Query: 798 ENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIGD----- 851
EN E+ M ++ATD D N + F YTL ++ + +GD
Sbjct: 3364 ENEP-PNELIM--TLRATDPDSNPNPSQFTYTLL--------TSPDSSAFRLVGDELRTT 3412
Query: 852 -SLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDENDNKPEFNQ 895
+LDRE K Y + + A D + +S+ + + I I D NDN Q
Sbjct: 3413 QTLDREVKSDYYIQIEASDGESPAMSATSTIHITIADRNDNPSTLRQ 3459
Score = 100 bits (240), Expect = 3e-19
Identities = 120/467 (25%), Positives = 190/467 (40%), Gaps = 60/467 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
FL+PE+ +G + + A D D+GLNG++ Y E A +V F ++
Sbjct: 1688 FLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEE--------GAPGEDV---FYLDPA 1736
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + +SL E + + + A D G+ + +V + V+DVND+ PV+ Y+
Sbjct: 1737 TGAFRLQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEE 1796
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E + + ATD D G N L + I D F + P G + LDRE E
Sbjct: 1797 VPEDVAIGTSVVTLTATDLDSGSNGELQFSIASGDPSQRFTVYP-NGTIVTIKNLDREPE 1855
Query: 1114 DKYILTVVARDN--GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
Y L VVA D D+NDN+P+F D + E E +
Sbjct: 1856 SFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTNPDSV------EIAEDTRT 1909
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ------ 1225
N +M++ +E N+ + + GN + L +
Sbjct: 1910 NV-IIMVLRAEDDDVERNSYVEYYLLTPGVPFAVSRVEGNMQVTGPLDRETESSYALLVQ 1968
Query: 1226 --NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ G P SST L + + DV D + P F YE ++E+ +E + + ++
Sbjct: 1969 ATDKGTPPQSSTMNLTIYITDVND-----NAPAFSMTPYEATLDEDTPVGLEFLKVTASD 2023
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
E N +RY I + D R F IDP G L + + E + +Y + VRA+ Q YS
Sbjct: 2024 PDEGLNSIIRYSIFS---GDSGRAFAIDPVTGVLSVNSGLNYEQRSSYTLTVRAQDQGYS 2080
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
++ V V + + DVNDN+P F + P +
Sbjct: 2081 TQVS-----------------SVTVTITVADVNDNAPVFEDSYAPSI 2110
Score = 99.1 bits (236), Expect = 8e-19
Identities = 110/456 (24%), Positives = 191/456 (41%), Gaps = 39/456 (8%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E IG + ++A+D D G NG++ Y F + + A+ K V +R
Sbjct: 941 FYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTANHTLFTLNSVTGAITSK---VSLDR 997
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+V P R+ + L D+ V + V D+ND PVF + Y +V E
Sbjct: 998 ES--LVEAGQPTTFSIRVRVHDSGQPQLQDHADVNIHVVDINDSPPVFNRESYQASVSEL 1055
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
++ +V ATD D G N+ + Y I + + F I + G + + LDRE + Y+
Sbjct: 1056 AQNETLIIRVSATDDDVGDNSYILYSIVSGNEEKRFHIDHVHGQIVLIAPLDREVTEGYV 1115
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L V ARD G D ND+ P F + D E + E ++ +++
Sbjct: 1116 LRVKARDGG-IVPQESFVEVEITVLDENDHRPSF-SVDLQREIEVTECLQIG----DTIG 1169
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG---LILYSLPQRKNQQNL------- 1227
+ I N I T+ + + +G L Y + +Q +L
Sbjct: 1170 GVQATDMDINSNGQISYTITGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDG 1229
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVF-ISRYYELEIEENVNAPVELVSLNLTEHYE 1286
G PSL + +++ + D D + P+F E++ E+ V VS + ++
Sbjct: 1230 GSPSLQAVVSMVINIRDCND-----NSPIFAYVGVPEIDEEKPEGFEVVRVSASDSDSGV 1284
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N ++R+ I ++ + F IDP +G + DRE + I+ ++ +
Sbjct: 1285 NGEVRFSISSQRPSG--DFFAIDPESGWITTNSRIDRESE-----IMATDQFILTVHGTD 1337
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
+ PV E V VV+ ++D+NDN+P+FT+
Sbjct: 1338 LAVPV-----ESRRTATVDVVIFVRDINDNAPRFTS 1368
Score = 97.9 bits (233), Expect = 2e-18
Identities = 130/467 (27%), Positives = 201/467 (43%), Gaps = 49/467 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V +LD NDN PVF + Y S++ N + + V A D DL + ++ Y +
Sbjct: 1566 VQVTVNVLDENDNAPVFT-NGPYTASIRENVASNSPVKTVMATDADL--DTIIFYSIVDG 1622
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ T F I+ TG + E + L ++ASD + TI++
Sbjct: 1623 A----TDLFSIDSTTGQIRTRGVVDRESSAVYQLQLQASDGTLT--------STTTIDIN 1670
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGV 618
+ + P F + Y F V + +G VG + D A +V+Y ++ EEG
Sbjct: 1671 LLDENDND--PVFSLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVV---EEGA 1725
Query: 619 P----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDE 672
P F ++ +G + L Y + F V + + + ATV+ V DVND
Sbjct: 1726 PGEDVFYLDPATGAFRLQQSLD-YEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDN 1784
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIA 731
V ++P+ + +E AIG T ++ +G+ G ++F IA+ D +
Sbjct: 1785 NPV-----YNPVDYS-EEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIASG-DPSQRFT 1837
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNK--GVISGAGIYQVTIYIEDENDNPPVFEH 789
+ +GTI T K LDRE Y + V+A + QV+I + D NDN P F +
Sbjct: 1838 VYPNGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTN 1897
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
I E+++ I +++A D D N+ Y L G F V G ++
Sbjct: 1898 PDSVE-IAEDTRTNVIIM---VLRAEDDDVERNSYVEYYLLTPGVP-FAVSRVEGNMQVT 1952
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
G LDRE + Y L + A D G SS L I I D NDN P F+
Sbjct: 1953 GP-LDRETESSYALLVQATDKGTPPQSSTMNLTIYITDVNDNAPAFS 1998
Score = 94.3 bits (224), Expect = 2e-17
Identities = 109/427 (25%), Positives = 182/427 (42%), Gaps = 62/427 (14%)
Query: 927 FALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
+ +D + P+FL + E+I +G+ + + A D D G+N I Y + Y
Sbjct: 303 YVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSITGDEY---- 358
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFV 1035
+F I+ G V L E+ + L I+A D G + + + + +
Sbjct: 359 ----------GWFQIDNGTGLVTTREKLDHETAAQVTLTITASDQGLEPMANTTILTIDI 408
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
+DVND +PVF + Y+ VEE R ++ +V ATD D G N ++TY F +
Sbjct: 409 QDVNDEYPVFNQIAYSETVEENSPARDLI-QVLATDLDNGVNGDVTYTFSSDQYSGMFSL 467
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
P +G+L + LDRE +D Y L ++A D G D NDN P+FY +
Sbjct: 468 DPESGLLQITVPLDREEQDSYELEILASDGG-SPSLQATATVTIAVLDQNDNPPQFYPTE 526
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA-NDTDFIG----NG 1210
A + N + + + V AT + +G A +F+ +D+ +G
Sbjct: 527 YY-------ASVIENG--PAGLFVTVVSAT---DLDVGVNGAVIFSLSDSSKFQIDSYSG 574
Query: 1211 NGLILYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDE-VEMSDKPVFISRY 1261
N SL + + Q+ + + +A + VTV D D +E P
Sbjct: 575 NVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNP------ 628
Query: 1262 YELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
Y ++EEN E+ ++ T N ++ Y I+N + + FVID +G + S
Sbjct: 629 YRFQLEENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGL---FVIDFYSGVIKTTLSI 685
Query: 1322 DREVKDT 1328
DRE ++
Sbjct: 686 DREAHES 692
Score = 90.2 bits (214), Expect = 4e-16
Identities = 92/327 (28%), Positives = 146/327 (44%), Gaps = 27/327 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S+ +++T+YI DVNDN P F TPY T+DE TP G + F+ + A P + +
Sbjct: 1978 SSTMNLTIYITDVNDNAPAFSMTPYEATLDEDTPVGLE-FLKVTAS-DPDEGLNSIIRYS 2035
Query: 138 LTIFKDIRAFDRDKPN---TPNSDVHYS-------IVSGNDDGHFALESSHKPVLLLRKV 187
+ RAF D + NS ++Y V D G+ SS + + V
Sbjct: 2036 IFSGDSGRAFAIDPVTGVLSVNSGLNYEQRSSYTLTVRAQDQGYSTQVSSVTVTITVADV 2095
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D ++ + + +I+ + A D D GV + + L S + LF++
Sbjct: 2096 NDNAPVFEDSYAPSIMENNLPNADIV---QVRADDADSGVNGMINFRLESDYNG-LFTIG 2151
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
S +G + + + LD + + N F L V A P + + + + D ND+ PEF
Sbjct: 2152 STSGLIQVTEVLDYEDQ-----NEFELIVIAEDSGTPSHQTRTTMTLTVNDDNDHDPEFV 2206
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-FSIDPRSGWLTVRNQ 366
DFY ++ E+ V+QV ATD D Y+L+ G+ F+IDP G +
Sbjct: 2207 SDFYRATVSEDASADTFVIQVTATDVD--ATAALRYRLNSDIGSKFTIDPLGG--RILTT 2262
Query: 367 TVLDREAHSSLRMKVYAKETNPSVVGT 393
+LDRE SS + V + PS + T
Sbjct: 2263 GLLDREVQSSYLLTV-TVDDGPSRLAT 2288
Score = 88.6 bits (210), Expect = 1e-15
Identities = 91/327 (27%), Positives = 139/327 (42%), Gaps = 26/327 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVP 135
+ YL V V I DVNDN PIF T Y TV+E + G I G + I +
Sbjct: 73 TGYLIVNVTITDVNDNSPIFTQTTYFATVNESSAAGTSVVHLNATDIDQGSNGDIVYRLK 132
Query: 136 RGLTIFKDIRAFD---------RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
LT D A D R P N + V+ D G + SS +++
Sbjct: 133 NELT---DNFALDPDTGWITLLRQLPYVANG--YLFEVTATDKGSPSQSSSAFVNVMVED 187
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEP---IHAIDQDLGVGATLRYELISGNDRKL 243
D+ + I ASG E + P P + AID+D + + SGNDR
Sbjct: 188 ENDHSPVIEVLIPEIEASGVASISETMLPGPLFNLKAIDEDREENGRVSMSIHSGNDRND 247
Query: 244 FSLDSVN---GSLFLEKELDLDAEHNLQ-ANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
FS S++ G +F + A + + ++ L A + P + + I ++D
Sbjct: 248 FSGTSISLPTGDVFFLLRVSPSANIDREIIASYNLTFAAEDMGTPPRRTYRSIIIYVVDE 307
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRS 358
ND+ P F + Y ++E++ G V V ATD D+G N + Y + D G F ID +
Sbjct: 308 NDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSITGDEYGWFQIDNGT 367
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +T R + LD E + + + + A +
Sbjct: 368 GLVTTREK--LDHETAAQVTLTITASD 392
Score = 87.8 bits (208), Expect = 2e-15
Identities = 114/447 (25%), Positives = 184/447 (41%), Gaps = 60/447 (13%)
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPE-------NIPIGTTIIKLNALDLDSGLNGQIR 967
G T++E++ LD++ P+F +PE N +G D DS N I
Sbjct: 708 GQTVVEIE-----ILDINDNAPVFALPEDQVDVVENWAVGNKFYAAQVTDADSPPNNVIL 762
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP--PESEFRLNISALDGGN- 1024
Y+ + + F IN G + + + L PE E+ L I A D G
Sbjct: 763 YDLS--------------VNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQATDYGTP 808
Query: 1025 -LNDNISVRVFVKDVNDHFPVFKKTWYN-FNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
L+ ++++ V V+DVN++ PVF + + E+ ++ ATDAD G N ++Y
Sbjct: 809 PLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTNGLISY 868
Query: 1083 FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
I +TD F I P G++ V LDRE D+Y LT+ A D G
Sbjct: 869 RITSGNTD-SFGIFP-DGMVYVKRALDREQVDQYDLTIEATDGG-VPSMTSTLMLEIIVL 925
Query: 1143 DVNDNSP-------KFYAFDE-----LLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
D NDN P FY +E + H +++ N E N+
Sbjct: 926 DENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGG-NGELTYSFTANHTLFTLNS 984
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
G +KV + + G +S+ R + G P L A + + V D+ D
Sbjct: 985 VTGAITSKVSLDRESLVEAGQP-TTFSI--RVRVHDSGQPQLQDHADVNIHVVDIND--- 1038
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVI 1308
PVF Y+ + E ++ ++ T+ +N + Y I++ N+ + F I
Sbjct: 1039 --SPPVFNRESYQASVSELAQNETLIIRVSATDDDVGDNSYILYSIVSGNE---EKRFHI 1093
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIVRA 1335
D +G + L+ DREV + Y + V+A
Sbjct: 1094 DHVHGQIVLIAPLDREVTEGYVLRVKA 1120
Score = 81.8 bits (193), Expect = 1e-13
Identities = 57/165 (34%), Positives = 84/165 (50%), Gaps = 6/165 (3%)
Query: 991 YFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK 1046
+F + + G V + + L E F L I+A D N L+D + ++V V DVND+ P+F
Sbjct: 2448 HFGVGSQSGEVSIIKELDYEESKSFSLWIAATDTANTQLSDFVELQVSVLDVNDNAPLFD 2507
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
++ Y +V E Q + + V ATD D N +++Y I +T+ F+IS +GV++
Sbjct: 2508 QSVYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSYAITLGNTNNAFDISS-SGVITTTQ 2566
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRET YILTV A D G D+NDN F
Sbjct: 2567 PLDRETVASYILTVEATDGG-NPSQSGSAIVVVTVTDINDNRMSF 2610
Score = 80.2 bits (189), Expect = 4e-13
Identities = 128/569 (22%), Positives = 225/569 (39%), Gaps = 71/569 (12%)
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGD-ENDNKPEFN-QIEENSKVRIHRETKLNGTAGF 916
I+Y LS+ D G++ + ++ + D +N + E+N QI+ + L+ +
Sbjct: 761 ILYDLSVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQATD----YGTPPLSSSMNL 816
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
+ N + VD + + E+IP+ + +I A D D G NG I Y S
Sbjct: 817 LVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTNGLISYRITSG--- 873
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVR 1032
+ D+ + G V V R+L E ++ L I A DGG ++ + +
Sbjct: 874 -----NTDSFGI-------FPDGMVYVKRALDREQVDQYDLTIEATDGGVPSMTSTLMLE 921
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
+ V D ND+ P F YNF + E +G + A D D G N LTY + T
Sbjct: 922 IIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTANHT--L 979
Query: 1093 FEISPLTGVLSVNGELDRET------EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
F ++ +TG ++ LDRE+ + + V D+G D+ND
Sbjct: 980 FTLNSVTGAITSKVSLDRESLVEAGQPTTFSIRVRVHDSG-QPQLQDHADVNIHVVDIND 1038
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
+ P F E EL+ N ++ + + +N+ I ++
Sbjct: 1039 SPPVFNR-----ESYQASVSELA-QNETLIIRVSATDDDVGDNSYILYSIVSGNEEKRFH 1092
Query: 1207 IGNGNGLILYSLP-QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD----KPVF-ISR 1260
I + +G I+ P R+ + L + ++ + V E+ + D +P F +
Sbjct: 1093 IDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQESFVEVEITVLDENDHRPSFSVDL 1152
Query: 1261 YYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
E+E+ E + + + T+ N ++ Y I N + F ++ +G +YL
Sbjct: 1153 QREIEVTECLQIGDTIGGVQATDMDINSNGQISYTITGGN---LDGVFGVNANSGEVYLT 1209
Query: 1319 RSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
D E Y + + A R S L + V +V+ I+D NDNSP
Sbjct: 1210 GYLDHEATSQYSLNITA-RDGGSPSLQAV----------------VSMVINIRDCNDNSP 1252
Query: 1379 KFTNGNRPLVTAIPTTAPFGYQVMQLKGA 1407
F P I P G++V+++ +
Sbjct: 1253 IFAYVGVP---EIDEEKPEGFEVVRVSAS 1278
Score = 80.2 bits (189), Expect = 4e-13
Identities = 84/378 (22%), Positives = 160/378 (42%), Gaps = 36/378 (9%)
Query: 29 RTHVSVILAQSID--SLVDSDSPQNVVKFRLGCDFDE---GDDLVRIGAGLNQISAY--- 80
R +VS + A +D SL+ + +++ D ++ G LV ++ S+
Sbjct: 1504 RYYVSAVTAGGVDKGSLIRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHV 1563
Query: 81 --LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGL 138
+ VTV + D NDN P+F + PY ++ E + + I ++ G
Sbjct: 1564 TSVQVTVNVLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDADLDTIIFYSIVDGA 1623
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE-SSHKPVLLLRKVLDY---DAGD 194
T D+ + D +T +V + L+ + L +D D D
Sbjct: 1624 T---DLFSID----STTGQIRTRGVVDRESSAVYQLQLQASDGTLTSTTTIDINLLDEND 1676
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGN--DRKLFSLDSV 249
+ + + ++ + E + + D D G+ + Y ++ +F LD
Sbjct: 1677 NDPVFSLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPA 1736
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G+ L++ LD + + + + + V A+ + +++ A V I + D+NDN P +
Sbjct: 1737 TGAFRLQQSLDYEVKQH-----YFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPV 1791
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQT 367
Y+ + E++ G SV+ + ATD D G NGE + + DP F++ P +T++N
Sbjct: 1792 DYSEEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIASGDPSQRFTVYPNGTIVTIKN-- 1849
Query: 368 VLDREAHSSLRMKVYAKE 385
LDRE S ++V A +
Sbjct: 1850 -LDREPESFYNLEVVASD 1866
Score = 79.8 bits (188), Expect = 5e-13
Identities = 53/171 (30%), Positives = 86/171 (50%), Gaps = 10/171 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+G + + Y ++SGN+ K F +D V+G + L LD + +VL+V+
Sbjct: 1065 VSATDDDVGDNSYILYSIVSGNEEKRFHIDHVHGQIVLIAPLDREVTEG-----YVLRVK 1119
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY-NISIVENLPNGFSVLQVMATDKDQG 336
A + + VEI +LD ND+ P F VD I + E L G ++ V ATD D
Sbjct: 1120 ARDGGIVPQESFVEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDIN 1179
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG+ +Y + + G F ++ SG + + LD EA S + + A++
Sbjct: 1180 SNGQISYTITGGNLDGVFGVNANSGEVYLTG--YLDHEATSQYSLNITARD 1228
Score = 79.8 bits (188), Expect = 5e-13
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 9/167 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+DQD G A + Y + GN + F +++ G + L K + L + + T+ L V+A+
Sbjct: 2849 AVDQDTGSNAAITYSISDGNGTEKFDVEADTGWI-LTKGVSLAGDVGI---TYQLLVKAT 2904
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
N K + V + D NDN P F+ D Y SI E++ G V V A D D G NG
Sbjct: 2905 DNGNIKKEDETTVTFLITDSNDNAPVFDDDTYRSSIAEDV--GGYVATVRAEDDDSGING 2962
Query: 340 EFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
E TY + A FSID SG +++ LDRE +++V A++
Sbjct: 2963 EITYSISGADAALFSIDAVSGIVSLVGS--LDRETSDEHQIQVTAED 3007
Score = 78.6 bits (185), Expect = 1e-12
Identities = 82/324 (25%), Positives = 141/324 (43%), Gaps = 18/324 (5%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDT-PYHVTVDELTPTGEKAFIFLI--APIGPSLT 129
G +S+ +++ V + DVN+N P+F+D+ + + E P L A G +
Sbjct: 806 GTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTNGL 865
Query: 130 IPLTVPRGLT----IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
I + G T IF D + + + D + + D G ++ S+ ++L
Sbjct: 866 ISYRITSGNTDSFGIFPDGMVYVKRALDREQVDQYDLTIEATDGGVPSMTST---LMLEI 922
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
VLD + F +I IHA+D D+G L Y + + LF
Sbjct: 923 IVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTANHT--LF 980
Query: 245 SLDSVNGSLFLEKELDLDAEHNL-QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
+L+SV G++ + LD ++ Q TF ++V+ P A V I ++D+ND+
Sbjct: 981 TLNSVTGAITSKVSLDRESLVEAGQPTTFSIRVRVHDSGQPQLQDHADVNIHVVDINDSP 1040
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P F + Y S+ E N +++V ATD D G+N Y + + + F ID G +
Sbjct: 1041 PVFNRESYQASVSELAQNETLIIRVSATDDDVGDNSYILYSIVSGNEEKRFHIDHVHGQI 1100
Query: 362 TVRNQTVLDREAHSSLRMKVYAKE 385
+ LDRE ++V A++
Sbjct: 1101 VL--IAPLDREVTEGYVLRVKARD 1122
Score = 78.2 bits (184), Expect = 2e-12
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+ + Y + GN +F +++ +G ++L LD +A + + L +
Sbjct: 1171 VQATDMDINSNGQISYTITGGNLDGVFGVNANSGEVYLTGYLDHEA-----TSQYSLNIT 1225
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI-SIVENLPNGFSVLQVMATDKDQG 336
A +P A + I + D NDN P F + + I E P GF V++V A+D D G
Sbjct: 1226 ARDGGSPSLQAVVSMVINIRDCNDNSPIFA--YVGVPEIDEEKPEGFEVVRVSASDSDSG 1283
Query: 337 ENGEFTYQLDD--PKG-AFSIDPRSGWLTVRNQTVLDREA 373
NGE + + P G F+IDP SGW+T ++ +DRE+
Sbjct: 1284 VNGEVRFSISSQRPSGDFFAIDPESGWITTNSR--IDRES 1321
Score = 77.8 bits (183), Expect = 2e-12
Identities = 108/465 (23%), Positives = 181/465 (38%), Gaps = 39/465 (8%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
Y Q+ S V V +T+ D NDN PVF S Y S+ N I +V+A D D G NGM
Sbjct: 2079 YSTQVSS-VTVTITVADVNDNAPVFEDS--YAPSIMENNLPNADIVQVRADDADSGVNGM 2135
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLA 553
+ + L+ N F I +G + V E E ++ + ++ PS + +
Sbjct: 2136 INFRLESDYN----GLFTIGSTSGLIQVTEVLDYEDQNEFELIVIAEDSGTPSHQTRTTM 2191
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+T+ N D P+F+ Y V + T V Q+ D + Y L
Sbjct: 2192 TLTV-----NDDNDHD-PEFVSDFYRATVSEDASADTFVIQVTATDVDATAALRYRL--N 2243
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+ G F ++ G I L R + Y V + + + T+ V V+DVND
Sbjct: 2244 SDIGSKFTIDPLGGRILTTGLLDREVQSSY-LLTVTVDDGPSRLATTSVRVEVLDVNDNP 2302
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+++ + + A Q T++ +R+ I + D + +
Sbjct: 2303 PRFSPTSYTATLPATSQQGCFVAAIQATDTDLED-----NAAIRYSITS-GDTSKFVVDQ 2356
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G + T + ++ Y + + AE V SG ++ + +F A++
Sbjct: 2357 DTGVVITAQGF-TDENSPYDLQITAE---NVASGQNSAVASLRV--------IFSTASFP 2404
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDS 852
S + + + T + Y++ G E F V +G V I +
Sbjct: 2405 DITFPFSGTSSSYGENVMTGMTVTTVTAIGIVTYSIAGGNHGEHFGVGSQSGEVSIIKE- 2463
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
LD E+ + L + A DT LS EL + + D NDN P F+Q
Sbjct: 2464 LDYEESKSFSLWIAATDTANTQLSDFVELQVSVLDVNDNAPLFDQ 2508
Score = 76.6 bits (180), Expect = 5e-12
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 4/155 (2%)
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
++ T LDRE D Y + + A N G V + I D NDN P+F TY +
Sbjct: 43 SLVTNSLLDRETEDFYILNISATDNSST-PRTGYLIVNVTITDVNDNSPIFTQTTYFATV 101
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E+S GT + + ATD D+G+N +Y L E + F +D +TG + +
Sbjct: 102 NESSAAGTSVVH---LNATDIDQGSNGDIVYRLKNELTDNFALDPDTGWITLLRQLPYVA 158
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+++++ + + SS A + +M+ DEND+ P
Sbjct: 159 NGYLFEVTATDKGSPSQSSSAFVNVMVEDENDHSP 193
Score = 76.2 bits (179), Expect = 7e-12
Identities = 65/216 (30%), Positives = 102/216 (47%), Gaps = 20/216 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P+G +K+ A D D GLN IRY S S D+ R F I+ G
Sbjct: 2006 LDEDTPVGLEFLKVTASDPDEGLNSIIRY----------SIFSGDS---GRAFAIDPVTG 2052
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V L E S + L + A D G +++V + V DVND+ PVF+ + Y ++
Sbjct: 2053 VLSVNSGLNYEQRSSYTLTVRAQDQGYSTQVSSVTVTITVADVNDNAPVFEDS-YAPSIM 2111
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V A DAD G N + + ++ SD + F I +G++ V LD E +++
Sbjct: 2112 ENNLPNADIVQVRADDADSGVNGMINFRLE-SDYNGLFTIGSTSGLIQVTEVLDYEDQNE 2170
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ L V+A D+G D ND+ P+F
Sbjct: 2171 FELIVIAEDSGTPSHQTRTTMTLTVNDD-NDHDPEF 2205
Score = 75.8 bits (178), Expect = 9e-12
Identities = 97/376 (25%), Positives = 155/376 (41%), Gaps = 26/376 (6%)
Query: 11 QPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL--- 67
+P E L T DLN VI+ + L D V+K L D + +
Sbjct: 637 RPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYSGVIKTTLSIDREAHESASFR 696
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----AP 123
+ + A + V + I D+NDN P+F V V E G K + + +P
Sbjct: 697 LTVLAVDGSQNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYAAQVTDADSP 756
Query: 124 IGPSLTIPLTVPR----GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
+ L+V G+ + ++D N P + + I D G L SS
Sbjct: 757 PNNVILYDLSVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQI-QATDYGTPPLSSSMN 815
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI--DQDLGVGATLRYELIS 237
LL V D + F I + + + IHA+ D D G + Y + S
Sbjct: 816 ---LLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTNGLISYRITS 872
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN F + +G +++++ LD + Q + + L ++A+ P T+ +EI +L
Sbjct: 873 GNTDS-FGIFP-DGMVYVKRALDRE-----QVDQYDLTIEATDGGVPSMTSTLMLEIIVL 925
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
D NDN P F+ YN + E G +V + A D D G NGE TY F+++
Sbjct: 926 DENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTANHTLFTLNSV 985
Query: 358 SGWLTVRNQTVLDREA 373
+G +T ++ LDRE+
Sbjct: 986 TGAIT--SKVSLDRES 999
Score = 75.8 bits (178), Expect = 9e-12
Identities = 79/327 (24%), Positives = 150/327 (45%), Gaps = 28/327 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTI 130
G + S+ +V + +EDVNDN P++ Y V E G + G + +
Sbjct: 1764 GSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDVAIGTSVVTLTATDLDSGSNGEL 1823
Query: 131 PLTVPRG-----LTIFKD-----IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKP 180
++ G T++ + I+ DR+ + N +V S ++ + + + S+ +
Sbjct: 1824 QFSIASGDPSQRFTVYPNGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRS--STAQV 1881
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+++ + D V +A R + I+ + A D D+ + + Y L++
Sbjct: 1882 SIIVTDINDNAPRFTNPDSVEIAEDTRTNVIIMV---LRAEDDDVERNSYVEYYLLTPGV 1938
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
F++ V G++ + LD + E +++ L VQA+ P +++ + I + D+N
Sbjct: 1939 P--FAVSRVEGNMQVTGPLDRETE-----SSYALLVQATDKGTPPQSSTMNLTIYITDVN 1991
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRS 358
DN P F + Y ++ E+ P G L+V A+D D+G N Y + D AF+IDP +
Sbjct: 1992 DNAPAFSMTPYEATLDEDTPVGLEFLKVTASDPDEGLNSIIRYSIFSGDSGRAFAIDPVT 2051
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G L+V + L+ E SS + V A++
Sbjct: 2052 GVLSVNSG--LNYEQRSSYTLTVRAQD 2076
Score = 75.4 bits (177), Expect = 1e-11
Identities = 111/414 (26%), Positives = 179/414 (43%), Gaps = 60/414 (14%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G + ++A DLD G+NG + + + SK F I+ G+V
Sbjct: 533 ENGPAGLFVTVVSATDLDVGVNGAVIFSLSDS-----SK-----------FQIDSYSGNV 576
Query: 1002 IVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEA 1057
SL E E + L ++A DG S +FV D D+ F+ Y F +EE
Sbjct: 577 TTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNPYRFQLEEN 636
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED--K 1115
+ R +G V AT D N +TY I D + F I +GV+ +DRE +
Sbjct: 637 RPNRTEVGTVLATSMDL--NVEITYVIVNGDPNGLFVIDFYSGVIKTTLSIDREAHESAS 694
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ LTV+A D D+NDN+P F A E + D + N +
Sbjct: 695 FRLTVLAVDG----SQNGQTVVEIEILDINDNAPVF-ALPE------DQVDVVENWAVGN 743
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIG--NGNGLI-----LYSLPQRK-NQQ-- 1225
+ T ++ P + + N D G + +G++ L + P+++ N Q
Sbjct: 744 KFY--AAQVTDADSPPNNVILYDLSVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQ 801
Query: 1226 --NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFI-SRYYELEIEENVNAPVELVSLNLT 1282
+ G P LSS+ L+VTV DV ++ PVF+ S L + E++ ++ T
Sbjct: 802 ATDYGTPPLSSSMNLLVTVRDV-----NNNAPVFVDSINTTLRLTESIPVNSIVIHALAT 856
Query: 1283 EHYENFK-MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + + Y + +TD +F I P +G +Y+ R+ DRE D Y++ + A
Sbjct: 857 DADQGTNGLISYRITSGNTD---SFGIFP-DGMVYVKRALDREQVDQYDLTIEA 906
Score = 74.5 bits (175), Expect = 2e-11
Identities = 66/217 (30%), Positives = 90/217 (41%), Gaps = 25/217 (11%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ N+P I+++ A D DSG+NG I + S+ F I
Sbjct: 2110 IMENNLP-NADIVQVRADDADSGVNGMINFRLESDY--------------NGLFTIGSTS 2154
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + V L E +EF L + A D G + ++ + V D NDH P F +Y V
Sbjct: 2155 GLIQVTEVLDYEDQNEFELIVIAEDSGTPSHQTRTTMTLTVNDDNDHDPEFVSDFYRATV 2214
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + +V ATD D A L Y + SD F I PL G + G LDRE +
Sbjct: 2215 SEDASADTFVIQVTATDVD--ATAALRYRLN-SDIGSKFTIDPLGGRILTTGLLDREVQS 2271
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y+LTV D DVNDN P+F
Sbjct: 2272 SYLLTVTVDDG---PSRLATTSVRVEVLDVNDNPPRF 2305
Score = 73.7 bits (173), Expect = 3e-11
Identities = 60/214 (28%), Positives = 93/214 (43%), Gaps = 16/214 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ N T ++++ A+D D+G N I Y + + AD + V G
Sbjct: 2834 VTANTRSNTRVLQVLAVDQDTGSNAAITYSISDGNGTEKFDVEADTGWILTKGV--SLAG 2891
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V + ++L + A D GN+ D +V + D ND+ PVF Y ++ A
Sbjct: 2892 DVGIT--------YQLLVKATDNGNIKKEDETTVTFLITDSNDNAPVFDDDTYRSSI--A 2941
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + V A D D G N +TY I +D L F I ++G++S+ G LDRET D++
Sbjct: 2942 EDVGGYVATVRAEDDDSGINGEITYSISGADAAL-FSIDAVSGIVSLVGSLDRETSDEHQ 3000
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ V A D DV+DN P F
Sbjct: 3001 IQVTAEDR-AMYSQSATAILIVTVTDVDDNPPVF 3033
Score = 73.3 bits (172), Expect = 5e-11
Identities = 92/388 (23%), Positives = 160/388 (41%), Gaps = 39/388 (10%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
S+ ++V D NDH P+F + Y + E+ + V ATDAD G NA++ Y I +
Sbjct: 299 SIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSITGDEY 358
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F+I TG+++ +LD ET + LT+ A D G DVND P
Sbjct: 359 GW-FQIDNGTGLVTTREKLDHETAAQVTLTITASDQG-LEPMANTTILTIDIQDVNDEYP 416
Query: 1150 KF--YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE--NAPIGTTVAKVFANDTD 1205
F A+ E +E P D +I V ++ N + T + +
Sbjct: 417 VFNQIAYSETVEENSPARD-----------LIQVLATDLDNGVNGDVTYTFSSDQYSGMF 465
Query: 1206 FIGNGNGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKP 1255
+ +GL+ ++P + +Q+ G PSL +TA + + V D D + P
Sbjct: 466 SLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQATATVTIAVLDQND-----NPP 520
Query: 1256 VFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
F Y + EN A + + ++ T+ + I + +D+ F ID +G +
Sbjct: 521 QFYPTEYYASVIENGPAGLFVTVVSATD-LDVGVNGAVIFSLSDSS---KFQIDSYSGNV 576
Query: 1316 YLVRSPDREVKDTYEVIVRA-ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
S DRE + +Y + V A + + I+ D L+ ++++ R + +
Sbjct: 577 TTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELN-PYRFQ-LE 634
Query: 1375 DNSPKFTNGNRPLVTAIPTTAPFGYQVM 1402
+N P T L T++ Y ++
Sbjct: 635 ENRPNRTEVGTVLATSMDLNVEITYVIV 662
Score = 73.3 bits (172), Expect = 5e-11
Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 8/144 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + Y ISG D LFS+D+V+G + L LD + Q +QV
Sbjct: 2951 VRAEDDDSGINGEITYS-ISGADAALFSIDAVSGIVSLVGSLDRETSDEHQ-----IQVT 3004
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A ++A A + + + D++DN P F Y + EN P+ V+ V ATD D G
Sbjct: 3005 AEDRAMYSQSATAILIVTVTDVDDNPPVFLPREYRADVFENSPSATPVVTVTATDADTGT 3064
Query: 338 NGEFTYQLDDPKGA--FSIDPRSG 359
N +F Y + G F+I+P +G
Sbjct: 3065 NADFEYIISGGDGTDFFTINPETG 3088
Score = 72.9 bits (171), Expect = 6e-11
Identities = 116/460 (25%), Positives = 182/460 (39%), Gaps = 57/460 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT I+ + A D G + +RY ++ K S V + R
Sbjct: 1478 VRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGVDKGSLIRASVTNGII---RTD 1533
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEE 1056
V+ L S + A+D + + +++ V V V D ND+ PVF Y ++ E
Sbjct: 1534 AVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGPYTASIRE 1593
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ + V ATDAD + + Y I TDL F I TG + G +DRE+ Y
Sbjct: 1594 NVASNSPVKTVMATDADL--DTIIFYSIVDGATDL-FSIDSTTGQIRTRGVVDRESSAVY 1650
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L + A D D NDN P F + PE DE+ E V
Sbjct: 1651 QLQLQASDG----TLTSTTTIDINLLDENDNDPVFSL--STYSFLVPE-DEMVG---EDV 1700
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFA--NDTDFIGNGNGL--ILYSLPQRKNQQ------- 1225
++ N + +V + A D ++ G + SL Q
Sbjct: 1701 GVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMA 1760
Query: 1226 -NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT-- 1282
+ G SSTA + + V DV D + PV+ Y E+ E+V +V+L T
Sbjct: 1761 TDKGSSPRSSTATVYINVEDVND-----NNPVYNPVDYSEEVPEDVAIGTSVVTLTATDL 1815
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
+ N ++++ I + D + F + P NGT+ +++ DRE + Y + V A
Sbjct: 1816 DSGSNGELQFSIAS---GDPSQRFTVYP-NGTIVTIKNLDREPESFYNLEVVASDMTLDP 1871
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
E +V + + D+NDN+P+FTN
Sbjct: 1872 --------------EDRRSSTAQVSIIVTDINDNAPRFTN 1897
Score = 72.9 bits (171), Expect = 6e-11
Identities = 82/300 (27%), Positives = 132/300 (44%), Gaps = 40/300 (13%)
Query: 122 APIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
+P + T+P T +G + I+A D D + N+ + YSI SG D F ++ V
Sbjct: 2306 SPTSYTATLPATSQQGCFVAA-IQATDTDLED--NAAIRYSITSG-DTSKFVVDQDTGVV 2361
Query: 182 LLLRKVLDYDAG-DKEFQLVIMASGKR--------IHKEILFPE---PIHAIDQDLG--- 226
+ + D ++ D + +ASG+ I FP+ P G
Sbjct: 2362 ITAQGFTDENSPYDLQITAENVASGQNSAVASLRVIFSTASFPDITFPFSGTSSSYGENV 2421
Query: 227 -VGATLR---------YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
G T+ Y + GN + F + S +G + + KELD + ++ +F L +
Sbjct: 2422 MTGMTVTTVTAIGIVTYSIAGGNHGEHFGVGSQSGEVSIIKELDYE-----ESKSFSLWI 2476
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ N + +++ +LD+NDN P F+ Y S+VE V+ V ATD+D
Sbjct: 2477 AATDTANTQLSDFVELQVSVLDVNDNAPLFDQSVYFTSVVEEQSGQVQVVSVSATDEDSL 2536
Query: 337 ENGEFTY--QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
NG+ +Y L + AF I SG +T LDRE +S + V A + NPS G+
Sbjct: 2537 SNGDVSYAITLGNTNNAFDIS-SSGVITTTQP--LDRETVASYILTVEATDGGNPSQSGS 2593
Score = 72.1 bits (169), Expect = 1e-10
Identities = 99/365 (27%), Positives = 146/365 (40%), Gaps = 29/365 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
++ + +V VTLL N+ P F + Y+F + +A G +G V A D DLG +G+V Y
Sbjct: 3118 MVDYAHVIVTLLGENEFYPQFT-QHQYDFYVNEHATDGAPVGVVLATDDDLGDDGIVNYL 3176
Query: 499 LQRTSNLTITSPFKINPNTGTVSVA-ESPILEGRHALFVEASDQPANP---SERRYSLAV 554
SNL F +N +G ++VA E+ L+ A V S N + A
Sbjct: 3177 FIGGSNL---QGFNVNLESGQITVAYENGRLDRETADTVLLSVLAKNEGPITGADIDEAE 3233
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE---QNDVSYDLL 611
V I V G D P F Y+ V + G+ V + D E +Y +L
Sbjct: 3234 VIIHVNDGN-----DAPVFSSEQYQARVLESEPPGSDVTVVTAADYDEIPSFRQFNYSIL 3288
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DV 669
G EG F ++ R+G IT L R +Y F VA + N A V V DV
Sbjct: 3289 RG-NEGDAFHIDARTGRITTASLLDRETLSVY-FLTVAAIDTGNPPQTGTAVVSVELDDV 3346
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND V + A +F + I + T+ S + + D +
Sbjct: 3347 NDNGPVFIGEAAEGSVF--ENEPPNELIMTLRATDPDS--NPNPSQFTYTLLTSPDSSAF 3402
Query: 730 IAIAEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ ++ + T + LDRE K D Y ++ +S +T I D NDNP
Sbjct: 3403 RLVGDE--LRTTQTLDREVKSDYYIQIEASDGESPAMSATSTIHIT--IADRNDNPSTLR 3458
Query: 789 HATYE 793
A E
Sbjct: 3459 QARIE 3463
Score = 70.5 bits (165), Expect = 3e-10
Identities = 112/486 (23%), Positives = 193/486 (39%), Gaps = 46/486 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
SFV VE+T+LD ND+ P F E + ++G IG V+A D D+ NG + Y +
Sbjct: 1130 SFVEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDINSNGQISYTI- 1188
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + F +N N+G V + E +++L + A D +PS + V+ I
Sbjct: 1189 --TGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARD-GGSPSLQAVVSMVINI- 1244
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
R N P I ++G P + G V ++ +D+ +V + +
Sbjct: 1245 --RDCNDNSP-IFAYVGVPE---IDEEKPEGFEVVRVSASDSDSGVNGEVRFSISSQRPS 1298
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT----NATVHVV----D 668
G FA++ SG IT + R + M + + +L++ ATV VV D
Sbjct: 1299 GDFFAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTATVDVVIFVRD 1358
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ND + I + SA + + H + NG + D
Sbjct: 1359 INDNAPRFTSQQAAAI---SRSTSANTRVTTV-HADDPDTGVNGQVTYTLISTGVPFRLD 1414
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I G + +P+ ++Y + + A + + + + I I D + +
Sbjct: 1415 LIT----GELTLTQPIP-SSANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQSSILNY 1469
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE---MFDVDENTG 844
TY G + EN GTEI + + + +D T ++ + G + + G
Sbjct: 1470 VQNTYTGSVRENQPAGTEI-VTVVAQYSDGRSATVRYYVSAVTAGGVDKGSLIRASVTNG 1528
Query: 845 VVKFIGDSLDREKKIMYKLSLVAR----DTGGLSS---EAELIIMIGDENDNKPEFNQIE 897
+++ LDRE + SLVA DT SS ++ + + DENDN P F
Sbjct: 1529 IIR-TDAVLDRE-DLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGP 1586
Query: 898 ENSKVR 903
+ +R
Sbjct: 1587 YTASIR 1592
Score = 69.3 bits (162), Expect = 8e-10
Identities = 100/406 (24%), Positives = 163/406 (40%), Gaps = 31/406 (7%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA-R 1005
G I ++A D D G NGQ+ Y + + + + + +++ +
Sbjct: 2728 GNVIATVSATDADDGDNGQVDYILKTMT----EHFRVETINNRGWIFPVPPISYIVPSPE 2783
Query: 1006 SLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE-EAQYTRR 1062
+ + ++ A+D G L SV + V N + PVF Y V + R
Sbjct: 2784 DTSNPNTYTFSVFAVDRGTPALYGEASVIITVTQDNSYTPVFATPSYFSPVTANTRSNTR 2843
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG-ELDRETEDKYILTVV 1121
VL +V A D D G NA +TY I + F++ TG + G L + Y L V
Sbjct: 2844 VL-QVLAVDQDTGSNAAITYSISDGNGTEKFDVEADTGWILTKGVSLAGDVGITYQLLVK 2902
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPV 1181
A DNG D NDN+P FD+ ++ A+++ +
Sbjct: 2903 ATDNGNIKKEDETTVTFLIT-DSNDNAP---VFDDDT-YRSSIAEDVGGYVATVRAEDDD 2957
Query: 1182 YKATIEENAPIGTTVAKVFAND--TDFIGNGNGLILYSLPQRKNQ---QNLGLPSLSSTA 1236
E I A +F+ D + + L + + + Q ++ + S S+TA
Sbjct: 2958 SGINGEITYSISGADAALFSIDAVSGIVSLVGSLDRETSDEHQIQVTAEDRAMYSQSATA 3017
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYI 1294
IL+VTV DV D + PVF+ R Y ++ EN + +V++ T + N Y I
Sbjct: 3018 ILIVTVTDVDD-----NPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADFEYII 3072
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREV-KDTYEVIVRAERQK 1339
+ TD F I+P G + + D E K TY + V A ++
Sbjct: 3073 SGGDGTDF---FTINPETGLILTQGNLDYETGKTTYHLTVAATNEQ 3115
Score = 68.5 bits (160), Expect = 1e-09
Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT---FVLQVQASQLN 282
G +T E +SG F L + E + L L T ++L + A+ +
Sbjct: 9 GYISTYLIESVSGGGDDAFLLQTFRPREDAEYTVSLVTNSLLDRETEDFYILNISATDNS 68
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
+ +T V + + D+NDN P F Y ++ E+ G SV+ + ATD DQG NG+
Sbjct: 69 STPRTGYLIVNVTITDVNDNSPIFTQTTYFATVNESSAAGTSVVHLNATDIDQGSNGDIV 128
Query: 343 YQL-DDPKGAFSIDPRSGWLTVRNQ 366
Y+L ++ F++DP +GW+T+ Q
Sbjct: 129 YRLKNELTDNFALDPDTGWITLLRQ 153
Score = 66.5 bits (155), Expect = 5e-09
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 7/173 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D + Y + GN F + S +G + + LD + +++L V+
Sbjct: 2528 VSATDEDSLSNGDVSYAITLGNTNNAFDISS-SGVITTTQPLDRET-----VASYILTVE 2581
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ NP ++ A V + + D+NDN F Y+ +I E+ P G V+ + TD D+
Sbjct: 2582 ATDGGNPSQSGSAIVVVTVTDINDNRMSF-TKMYDATIPEDAPPGTHVVTLHTTDPDENN 2640
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
+F+ + F+I+P +G +T+ + + EA L +K + +++ V
Sbjct: 2641 LSQFSIEAGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDSSHEV 2693
Score = 63.3 bits (147), Expect = 5e-08
Identities = 55/176 (31%), Positives = 82/176 (46%), Gaps = 17/176 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DL + Y ++ G LFS+DS G + +D ++ + + LQ+Q
Sbjct: 1604 VMATDADLDT--IIFYSIVDGAT-DLFSIDSTTGQIRTRGVVDRES-----SAVYQLQLQ 1655
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS + T+ ++I LLD NDN P F + Y+ + E+ G V V+ATD D G
Sbjct: 1656 AS---DGTLTSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGEDVGVVVATDPDAGL 1712
Query: 338 NGEFTYQLDDP----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
NGE Y + + + F +DP +G R Q LD E M V A + S
Sbjct: 1713 NGEVAYSVVEEGAPGEDVFYLDPATG--AFRLQQSLDYEVKQHYFMTVMATDKGSS 1766
Score = 61.7 bits (143), Expect = 2e-07
Identities = 81/333 (24%), Positives = 130/333 (39%), Gaps = 28/333 (8%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDE------LTPTGEKAFIFLIAPIGPSLT----IP 131
+VT I D NDN P+F D Y ++ E T E + I S++
Sbjct: 2916 TVTFLITDSNDNAPVFDDDTYRSSIAEDVGGYVATVRAEDDDSGINGEITYSISGADAAL 2975
Query: 132 LTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
++ I + + DR+ SD H V+ D A+ S +L+ V D D
Sbjct: 2976 FSIDAVSGIVSLVGSLDRE-----TSDEHQIQVTAEDR---AMYSQSATAILIVTVTDVD 3027
Query: 192 AGDKEFQLVIMASGKRIHKEILFPE-PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
F + + P + A D D G A Y + G+ F+++
Sbjct: 3028 DNPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDGTDFFTINPET 3087
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + + LD + T+ L V A+ A V + LL N+ P+F
Sbjct: 3088 GLILTQGNLDYETGKT----TYHLTVAATN-EQATMVDYAHVIVTLLGENEFYPQFTQHQ 3142
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQT- 367
Y+ + E+ +G V V+ATD D G++G Y F+++ SG +TV +
Sbjct: 3143 YDFYVNEHATDGAPVGVVLATDDDLGDDGIVNYLFIGGSNLQGFNVNLESGQITVAYENG 3202
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFADSQRI 400
LDRE ++ + V AK P + G D +
Sbjct: 3203 RLDRETADTVLLSVLAKNEGP-ITGADIDEAEV 3234
Score = 60.5 bits (140), Expect = 3e-07
Identities = 47/163 (28%), Positives = 75/163 (46%), Gaps = 9/163 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y ++ GN+ F +D+ G + LD + + + L V A NP +T A V
Sbjct: 3285 YSILRGNEGDAFHIDARTGRITTASLLDRET-----LSVYFLTVAAIDTGNPPQTGTAVV 3339
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-GEFTYQLDDPKGA 351
+EL D+NDN P F + S+ EN P ++ + ATD D N +FTY L +
Sbjct: 3340 SVELDDVNDNGPVFIGEAAEGSVFENEPPNELIMTLRATDPDSNPNPSQFTYTLLTSPDS 3399
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+ R +R LDRE S +++ A + +P++ T
Sbjct: 3400 SAF--RLVGDELRTTQTLDREVKSDYYIQIEASDGESPAMSAT 3440
Score = 59.7 bits (138), Expect = 6e-07
Identities = 87/335 (25%), Positives = 142/335 (42%), Gaps = 31/335 (9%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVP 135
SA + V + DV+DN P+FL Y V E +P+ A G + +
Sbjct: 3014 SATAILIVTVTDVDDNPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADFEYIIS 3073
Query: 136 RGLTIFKDIRAFDRDKPNTPN--SDVHYSIVSGNDDGHFALESSHKPVLLL--RKVLDYD 191
G D F P T + + +G H + ++++ ++ V+
Sbjct: 3074 GG-----DGTDFFTINPETGLILTQGNLDYETGKTTYHLTVAATNEQATMVDYAHVIVTL 3128
Query: 192 AGDKEF--QLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSL 246
G+ EF Q +++ P+ + D DLG + Y I G++ + F++
Sbjct: 3129 LGENEFYPQFTQHQYDFYVNEHATDGAPVGVVLATDDDLGDDGIVNYLFIGGSNLQGFNV 3188
Query: 247 DSVNGSLFLEKELD-LDAEHNLQANTFVLQVQASQLNNPLKTA---QARVEIELLDLNDN 302
+ +G + + E LD E A+T +L V A P+ A +A V I + D ND
Sbjct: 3189 NLESGQITVAYENGRLDRE---TADTVLLSVLAKN-EGPITGADIDEAEVIIHVNDGND- 3243
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-GEFTYQL--DDPKGAFSIDPRSG 359
P F + Y ++E+ P G V V A D D+ + +F Y + + AF ID R+G
Sbjct: 3244 APVFSSEQYQARVLESEPPGSDVTVVTAADYDEIPSFRQFNYSILRGNEGDAFHIDARTG 3303
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
+T ++LDRE S + V A +T NP GT
Sbjct: 3304 RIT--TASLLDRETLSVYFLTVAAIDTGNPPQTGT 3336
Score = 59.3 bits (137), Expect = 8e-07
Identities = 43/142 (30%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 1010 ESEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
E + LNISA D + + V V + DVND+ P+F +T Y V E+ + +
Sbjct: 55 EDFYILNISATDNSSTPRTGYLIVNVTITDVNDNSPIFTQTTYFATVNESSAAGTSVVHL 114
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
+ATD D G N ++ Y ++ TD F + P TG +++ +L + Y+ V A D G
Sbjct: 115 NATDIDQGSNGDIVYRLKNELTD-NFALDPDTGWITLLRQLP-YVANGYLFEVTATDKG- 171
Query: 1128 XXXXXXXXXXXXXXXDVNDNSP 1149
D ND+SP
Sbjct: 172 SPSQSSSAFVNVMVEDENDHSP 193
Score = 57.2 bits (132), Expect = 3e-06
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D GV +R+ + S F++D +G + +D ++E + + F+L V
Sbjct: 1275 VSASDSDSGVNGEVRFSISSQRPSGDFFAIDPESGWITTNSRIDRESEI-MATDQFILTV 1333
Query: 277 QASQLNNPL---KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ L P+ +TA V I + D+NDN P F +I + V V A D
Sbjct: 1334 HGTDLAVPVESRRTATVDVVIFVRDINDNAPRFTSQ-QAAAISRSTSANTRVTTVHADDP 1392
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
D G NG+ TY L F +D +G LT+
Sbjct: 1393 DTGVNGQVTYTLISTGVPFRLDLITGELTL 1422
Score = 56.0 bits (129), Expect = 7e-06
Identities = 33/118 (27%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
++ V VT+ D NDN+P+F + Y ++ ++ GT + + A D D G NG ++Y L+
Sbjct: 75 YLIVNVTITDVNDNSPIFTQTT-YFATVNESSAAGTSVVHLNATDIDQGSNGDIVYRLKN 133
Query: 502 TSNLTITSPFKINPNTGTVS-VAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+T F ++P+TG ++ + + P + + V A+D+ +PS+ + V +E
Sbjct: 134 ----ELTDNFALDPDTGWITLLRQLPYVANGYLFEVTATDK-GSPSQSSSAFVNVMVE 186
Score = 56.0 bits (129), Expect = 7e-06
Identities = 71/299 (23%), Positives = 120/299 (40%), Gaps = 27/299 (9%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVP 135
Q+S ++ + V + DVNDN P+F + Y +V E +G+ + + A SL+ V
Sbjct: 2485 QLSDFVELQVSVLDVNDNAPLFDQSVYFTSVVE-EQSGQVQVVSVSATDEDSLSNG-DVS 2542
Query: 136 RGLTIFKDIRAFD--------RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
+T+ AFD +P + Y + DG +S V++ V
Sbjct: 2543 YAITLGNTNNAFDISSSGVITTTQPLDRETVASYILTVEATDGGNPSQSGSAIVVVT--V 2600
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D + F + A+ +H D D ++ + +G LF+++
Sbjct: 2601 TDINDNRMSFTKMYDATIPEDAPPGTHVVTLHTTDPD--ENNLSQFSIEAGGQSSLFAIN 2658
Query: 248 SVNGSLFLEKELDLDAE--HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+ G + L LD + E H L +F +S Q +V + + D NDN P
Sbjct: 2659 PITGEITLNSSLDFEDEAVHYLLVKSF--DPDSSH------EVQTQVLVNVEDTNDNAPV 2710
Query: 306 FEVDFYNISIVENL-PNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP--RSGWL 361
F + N + E +G + V ATD D G+NG+ Y L F ++ GW+
Sbjct: 2711 FTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILKTMTEHFRVETINNRGWI 2769
Score = 54.8 bits (126), Expect = 2e-05
Identities = 51/187 (27%), Positives = 80/187 (42%), Gaps = 20/187 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ T +I++ A D+D+ +RY NS++ SK + D L G
Sbjct: 2214 VSEDASADTFVIQVTATDVDA--TAALRYRLNSDI---GSKFTIDPLG-----------G 2257
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++ L E S + L ++ DG + SVRV V DVND+ P F T Y +
Sbjct: 2258 RILTTGLLDREVQSSYLLTVTVDDGPSRLATTSVRVEVLDVNDNPPRFSPTSYTATLPAT 2317
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + ATD D NA + Y I DT F + TGV+ + + + Y
Sbjct: 2318 SQQGCFVAAIQATDTDLEDNAAIRYSITSGDTS-KFVVDQDTGVV-ITAQGFTDENSPYD 2375
Query: 1118 LTVVARD 1124
L + A +
Sbjct: 2376 LQITAEN 2382
Score = 53.6 bits (123), Expect = 4e-05
Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 9/137 (6%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ A LRY L S K F++D + G + LD + + ++++L V +
Sbjct: 2231 DVDATAALRYRLNSDIGSK-FTIDPLGGRILTTGLLDREVQ-----SSYLLTVTVD--DG 2282
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
P + A V +E+LD+NDN P F Y ++ G V + ATD D +N Y
Sbjct: 2283 PSRLATTSVRVEVLDVNDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLEDNAAIRY 2342
Query: 344 QL-DDPKGAFSIDPRSG 359
+ F +D +G
Sbjct: 2343 SITSGDTSKFVVDQDTG 2359
Score = 53.6 bits (123), Expect = 4e-05
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
E NT+ V A P +A V I + N P F Y + N +
Sbjct: 2783 EDTSNPNTYTFSVFAVDRGTPALYGEASVIITVTQDNSYTPVFATPSYFSPVTANTRSNT 2842
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVR 364
VLQV+A D+D G N TY + D G F ++ +GW+ +
Sbjct: 2843 RVLQVLAVDQDTGSNAAITYSISDGNGTEKFDVEADTGWILTK 2885
Score = 53.2 bits (122), Expect = 5e-05
Identities = 66/252 (26%), Positives = 106/252 (42%), Gaps = 25/252 (9%)
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
++ N T+ DVND + + + + N + AA + H N + I G++
Sbjct: 76 LIVNVTI--TDVNDNSPIFTQTTYFATV-----NESSAAGTSVVHLNATDIDQGSNGDIV 128
Query: 718 FLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+ + N+ +TD+ A+ D G I + L Y V A +KG S + V +
Sbjct: 129 YRLKNE--LTDNFALDPDTGWITLLRQLPYVANG-YLFEVTAT-DKGSPSQSSSAFVNVM 184
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI--IKATDADEGTNALFMYTLF-GEG 833
+EDEND+ PV E E + I + + +KA D D N ++ G
Sbjct: 185 VEDENDHSPVIEVLIPEIEASGVASISETMLPGPLFNLKAIDEDREENGRVSMSIHSGND 244
Query: 834 KEMF---DVDENTGVVKFI-----GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
+ F + TG V F+ ++DRE Y L+ A D G + +II +
Sbjct: 245 RNDFSGTSISLPTGDVFFLLRVSPSANIDREIIASYNLTFAAEDMGTPPRRTYRSIIIYV 304
Query: 884 GDENDNKPEFNQ 895
DEND+ P F Q
Sbjct: 305 VDENDHAPMFLQ 316
Score = 48.4 bits (110), Expect = 0.002
Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 9/144 (6%)
Query: 1011 SEFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+ + L + A DGGN + + S V V V D+ND+ F K + E+A V+ +
Sbjct: 2574 ASYILTVEATDGGNPSQSGSAIVVVTVTDINDNRMSFTKMYDATIPEDAPPGTHVV-TLH 2632
Query: 1069 ATDADFGQNANLTYF-IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
TD D +N NL+ F I+ F I+P+TG +++N LD E E + L V + D
Sbjct: 2633 TTDPD--EN-NLSQFSIEAGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFD--P 2687
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKF 1151
D NDN+P F
Sbjct: 2688 DSSHEVQTQVLVNVEDTNDNAPVF 2711
Score = 48.4 bits (110), Expect = 0.002
Identities = 43/137 (31%), Positives = 53/137 (38%), Gaps = 4/137 (2%)
Query: 1016 NISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-F 1074
N + G ++ D V + V D ND PVF Y V E++ + V A D D
Sbjct: 3220 NEGPITGADI-DEAEVIIHVNDGNDA-PVFSSEQYQARVLESEPPGSDVTVVTAADYDEI 3277
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
Y I + F I TG ++ LDRET Y LTV A D G
Sbjct: 3278 PSFRQFNYSILRGNEGDAFHIDARTGRITTASLLDRETLSVYFLTVAAIDTG-NPPQTGT 3336
Query: 1135 XXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 3337 AVVSVELDDVNDNGPVF 3353
Score = 48.4 bits (110), Expect = 0.002
Identities = 46/161 (28%), Positives = 66/161 (40%), Gaps = 8/161 (4%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F I+ R G + A L E S + L ++A+D GN V V + DVND+ PVF
Sbjct: 3296 FHIDARTGRITTASLLDRETLSVYFLTVAAIDTGNPPQTGTAVVSVELDDVNDNGPVFIG 3355
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+V E + ++ + ATD D N + TY + S F + + L
Sbjct: 3356 EAAEGSVFENEPPNELIMTLRATDPDSNPNPSQFTYTLLTSPDSSAFRL--VGDELRTTQ 3413
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
LDRE + Y + + A D G D NDN
Sbjct: 3414 TLDREVKSDYYIQIEASD-GESPAMSATSTIHITIADRNDN 3453
Score = 41.9 bits (94), Expect = 0.13
Identities = 26/60 (43%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
P E + T L N LDRETED YIL + A DN DVNDNSP F
Sbjct: 34 PREDAEYTVSLVTNSLLDRETEDFYILNISATDN-SSTPRTGYLIVNVTITDVNDNSPIF 92
Score = 40.7 bits (91), Expect = 0.30
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
+A D D GIN +I Y I A F+ID VSG V +V +L R+
Sbjct: 2952 RAEDDDSGINGEITYSISGADAALFSIDAVSGIVSLVGSLDRE 2994
Score = 37.1 bits (82), Expect = 3.7
Identities = 17/39 (43%), Positives = 24/39 (61%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAAL 1479
ATD D G N DI Y++ NE FA+DP +G + ++ L
Sbjct: 116 ATDIDQGSNGDIVYRLKNELTDNFALDPDTGWITLLRQL 154
Score = 36.7 bits (81), Expect = 4.9
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 1441 ATDSDIGINADIRYQILNEQAPR-FAIDPVSGTVRVVAAL 1479
A+D D G+N+ IRY I + + R FAIDPV+G + V + L
Sbjct: 2021 ASDPDEGLNSIIRYSIFSGDSGRAFAIDPVTGVLSVNSGL 2060
Score = 36.3 bits (80), Expect = 6.5
Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 1441 ATDSDIGINADIRYQILNEQ-APRFAIDPVSGTVRVVAALARD 1482
ATD D G+N D+ Y ++Q + F++DP SG +++ L R+
Sbjct: 441 ATDLDNGVNGDVTYTFSSDQYSGMFSLDPESGLLQITVPLDRE 483
>UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep:
ENSANGP00000001238 - Anopheles gambiae str. PEST
Length = 3543
Score = 149 bits (360), Expect = 8e-34
Identities = 167/681 (24%), Positives = 290/681 (42%), Gaps = 77/681 (11%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
L+ + +F +DS G + LD + + +V A+ + P ++ +++
Sbjct: 402 LLDSRSQAMFKVDSRTGVVTTSSTLDREL-----MDVHYFRVIATDDSFPPRSGTTTLQV 456
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
+LD ND+ P FE + ++ ++ E + G +V+ + ATD+D G+N + Y + G
Sbjct: 457 NVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILG---- 512
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQ-PLETNAP 413
NQ A+ S E NP + SQ+ R + T +
Sbjct: 513 ---------ENQEQSGTAANGS-------NEGNPVEGDSNGSSQKFRIDARSCTISTRSA 556
Query: 414 LEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN- 472
L++ + T T+ E+ + V V +LD NDN P F Y ++ +
Sbjct: 557 LDREVSGMYTIMVTATDMATPQSERKSATTTVLVKILDDNDNYPQF-SERTYTVQVREDQ 615
Query: 473 -AKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG- 530
A VI ++A D D G N + Y + + S F I+ +G VS+ + E
Sbjct: 616 WANENNVIAHIQASDADQGNNAAIRYAIIGGNT---QSQFSIDSMSGDVSLVKPLDYENV 672
Query: 531 -RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG 589
+ L + A D +PS + +V + + P F + ++ V +V +G
Sbjct: 673 RSYRLVIRAQD-GGSPSRSNTTQLLVNV------LDANDNAPRFYTSQFQEAVLESVPVG 725
Query: 590 TSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEA 647
++ +++ D+ E ++++Y + ++G+P AV+ R+G I L R + Y F+
Sbjct: 726 YNIVRVQAYDSDEGANSEITYS-IQNRDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQV 784
Query: 648 VALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
VA+ S T+ V + DVND + ++ ++ G + + T+
Sbjct: 785 VAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYEAML--AEDQPPGTPVTTVTATDPD 842
Query: 707 S----IYGNGTGNV--RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF 760
Y GN RF I +Q G I +PLD ++ + +T+ A
Sbjct: 843 EDSRLHYEITAGNTRGRFAITSQNG---------RGLITIAQPLDYKQERRFALTITAT- 892
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ G + I V I I D N+ PVFE+A Y + E++ IGT + ++ A+D+D G
Sbjct: 893 DSGQRTDTAI--VNINITDANNFAPVFENAPYSASVFEDAPIGTTVL---VVSASDSDVG 947
Query: 821 TNALFMYTLFGE------GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--G 872
NA Y L E E F ++ TG + LDRE Y L++ A+D G
Sbjct: 948 INAQITYLLNDESVNGLGANEPFTINAQTGAI-ITNAKLDRESTSGYLLTVTAKDGGNPS 1006
Query: 873 LSSEAELIIMIGDENDNKPEF 893
LS ++ I + D NDN P F
Sbjct: 1007 LSDTTDVEISVTDVNDNAPVF 1027
Score = 129 bits (312), Expect = 5e-28
Identities = 129/457 (28%), Positives = 201/457 (43%), Gaps = 30/457 (6%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V +LDANDN P F S E ++S VG I +V+A D D G N + Y +Q +
Sbjct: 697 VNVLDANDNAPRFYTSQFQEAVLES-VPVGYNIVRVQAYDSDEGANSEITYSIQNRDD-- 753
Query: 507 ITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
P ++P TG + ++ E R++ V A D P S+ +VTI+
Sbjct: 754 -GMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSV-IVTIQDV---- 807
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
N D P F YE + + GT V + D E + + Y++ G G FA+
Sbjct: 808 -NDND-PTFSPKYYEAMLAEDQPPGTPVTTVTATDPDEDSRLHYEITAGNTRG-RFAITS 864
Query: 625 RSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
++G +IT+ L Y + + ++ + +++ D N+ V +S
Sbjct: 865 QNGRGLITIAQPLD-YKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYS 923
Query: 683 PIIFHVKENSAGAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFT 740
+F ++ G + + ++ I T + N + I A+ G I T
Sbjct: 924 ASVF--EDAPIGTTVLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIIT 981
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
LDRE Y +TV A+ + G S + V I + D NDN PVF+ Y+ I E++
Sbjct: 982 NAKLDRESTSGYLLTVTAK-DGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIPEDA 1040
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDSLDREKK 858
IGT + I ATD D G N Y L + + F VD +GV++ LDRE
Sbjct: 1041 LIGTSVVQ---IAATDLDMGLNGRVKYALGQKDMDEGSFVVDPISGVIR-TNKGLDRESI 1096
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+Y L+ +A D G +SS E+ I + D ND+ P F
Sbjct: 1097 PVYHLTAIASDKGTPTMSSSVEVQIRLDDVNDSPPTF 1133
Score = 122 bits (294), Expect = 8e-26
Identities = 126/464 (27%), Positives = 205/464 (44%), Gaps = 40/464 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V VT+ D NDN+P F P YE + + GT + V A DPD ++ + Y++
Sbjct: 799 SVIVTIQDVNDNDPTFSPK-YYEAMLAEDQPPGTPVTTVTATDPD--EDSRLHYEIT-AG 854
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
N G +++A+ P+ E R AL + A+D S +R A+V I +T
Sbjct: 855 NTRGRFAITSQNGRGLITIAQ-PLDYKQERRFALTITATD-----SGQRTDTAIVNINIT 908
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL----LHGY 614
P F APY V + IGT+V + +D+ ++Y L ++G
Sbjct: 909 DANNF----APVFENAPYSASVFEDAPIGTTVLVVSASDSDVGINAQITYLLNDESVNGL 964
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDER 673
PF + ++G I L R + Y A N +LS T+ + V DVND
Sbjct: 965 GANEPFTINAQTGAIITNAKLDRESTSGYLLTVTAKDGGNPSLSDTTDVEISVTDVNDNA 1024
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V + I ++ G ++ QI T++ G V++ + Q+D+ + +
Sbjct: 1025 PVFKVPLYQATI--PEDALIGTSVVQIAATDLDM---GLNGRVKYALG-QKDMDEGSFVV 1078
Query: 734 E--DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G I T K LDRE VY +T IA +KG + + +V I ++D ND+PP F
Sbjct: 1079 DPISGVIRTNKGLDRESIPVYHLTAIAS-DKGTPTMSSSVEVQIRLDDVNDSPPTFASDK 1137
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK--- 847
++ ENS +G+ + I A D DEG NA+ Y++ G+ F + G +
Sbjct: 1138 LTLYVPENSPVGSVV---GEIYAHDPDEGVNAIVHYSIIGGDDSNSFSLVTRPGSDRAQL 1194
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
LD E ++ + L ++ + I++ D NDN P
Sbjct: 1195 LTMTELDYESPRKRFELIIRAASPPLRNDVYVEILVTDVNDNAP 1238
Score = 119 bits (287), Expect = 5e-25
Identities = 108/372 (29%), Positives = 162/372 (43%), Gaps = 53/372 (14%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I + N FA + + E+ PIGTT++ ++A D D G+N QI Y N E
Sbjct: 905 INITDANNFAPVFENAPYSASVFEDAPIGTTVLVVSASDSDVGINAQITYLLNDE----- 959
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVF 1034
S + L F IN + G +I L ES + L ++A DGGN L+D V +
Sbjct: 960 ---SVNGLGANEPFTINAQTGAIITNAKLDRESTSGYLLTVTAKDGGNPSLSDTTDVEIS 1016
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-PF 1093
V DVND+ PVFK Y + E + ++ ATD D G N + Y + D D F
Sbjct: 1017 VTDVNDNAPVFKVPLYQATIPEDALIGTSVVQIAATDLDMGLNGRVKYALGQKDMDEGSF 1076
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+ P++GV+ N LDRE+ Y LT +A D G DVND+ P F A
Sbjct: 1077 VVDPISGVIRTNKGLDRESIPVYHLTAIASDKG-TPTMSSSVEVQIRLDDVNDSPPTF-A 1134
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
D+L + +P EN+P+G+ V +++A+D D N +
Sbjct: 1135 SDKL------------------TLYVP-------ENSPVGSVVGEIYAHDPD--EGVNAI 1167
Query: 1214 ILYSLPQRKNQQNLGL---PSLSSTAILMVTVADVPDE-------VEMSDKPVFISRYYE 1263
+ YS+ + + L P +L +T D + + P+ Y E
Sbjct: 1168 VHYSIIGGDDSNSFSLVTRPGSDRAQLLTMTELDYESPRKRFELIIRAASPPLRNDVYVE 1227
Query: 1264 LEIEE-NVNAPV 1274
+ + + N NAPV
Sbjct: 1228 ILVTDVNDNAPV 1239
Score = 105 bits (251), Expect = 1e-20
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 9/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G A +RY +I GN + FS+DS++G + L K LD + ++ L ++
Sbjct: 626 IQASDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYE-----NVRSYRLVIR 680
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P ++ ++ + +LD NDN P F + +++E++P G+++++V A D D+G
Sbjct: 681 AQDGGSPSRSNTTQLLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGA 740
Query: 338 NGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N E TY + D ++DPR+GW + LDRE S +V A
Sbjct: 741 NSEITYSIQNRDDGMPLAVDPRTGW--IHTTKALDREEQSRYSFQVVA 786
Score = 97.1 bits (231), Expect = 3e-18
Identities = 108/489 (22%), Positives = 199/489 (40%), Gaps = 47/489 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL----- 499
++V +LD ND+ P F + + +++ VG+ + ++A D D+G+N + Y +
Sbjct: 454 LQVNVLDCNDHTPTF-EAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILG 512
Query: 500 --QRTSNLTI----------------TSPFKINPNTGTVSVAESPILE--GRHALFVEAS 539
Q S + F+I+ + T+S + E G + + V A+
Sbjct: 513 ENQEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTAT 572
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRV 597
D SER+ + V +++ + + P F Y V + + + I+
Sbjct: 573 DMATPQSERKSATTTVLVKIL----DDNDNYPQFSERTYTVQVREDQWANENNVIAHIQA 628
Query: 598 NDAFEQND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA- 654
+DA + N+ + Y ++ G + F+++ SG +++V L N Y A +
Sbjct: 629 SDADQGNNAAIRYAIIGGNTQS-QFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSP 687
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+ S T V+V+D ND + Q + ++ +
Sbjct: 688 SRSNTTQLLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGA-----NS 742
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ + I N+ D G I T K LDRE++ Y V+A + G+ + V
Sbjct: 743 EITYSIQNRDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQVVA-VDGGIPPKSASTSVI 801
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ I+D NDN P F YE + E+ GT + + ATD DE + + T G +
Sbjct: 802 VTIQDVNDNDPTFSPKYYEAMLAEDQPPGTPV---TTVTATDPDEDSRLHYEITA-GNTR 857
Query: 835 EMFDVDENTGV-VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
F + G + I LD +++ + L++ A D+G + A + I I D N+ P F
Sbjct: 858 GRFAITSQNGRGLITIAQPLDYKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVF 917
Query: 894 NQIEENSKV 902
++ V
Sbjct: 918 ENAPYSASV 926
Score = 96.7 bits (230), Expect = 4e-18
Identities = 76/240 (31%), Positives = 111/240 (46%), Gaps = 40/240 (16%)
Query: 992 FVINERHGHVIVARSLP----PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F I ++G ++ + P E F L I+A D G D V + + D N+ PVF+
Sbjct: 860 FAITSQNGRGLITIAQPLDYKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVFEN 919
Query: 1048 TWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-----TDLPFEISPLTGV 1101
Y+ +V E+A VL V A+D+D G NA +TY + + PF I+ TG
Sbjct: 920 APYSASVFEDAPIGTTVL-VVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGA 978
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ N +LDRE+ Y+LTV A+D G DVNDN+P F
Sbjct: 979 IITNAKLDRESTSGYLLTVTAKDGG-NPSLSDTTDVEISVTDVNDNAPVF---------- 1027
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR 1221
+P+Y+ATI E+A IGT+V ++ A D D NG + Y+L Q+
Sbjct: 1028 ----------------KVPLYQATIPEDALIGTSVVQIAATDLDM--GLNGRVKYALGQK 1069
Score = 89.4 bits (212), Expect = 7e-16
Identities = 119/500 (23%), Positives = 200/500 (40%), Gaps = 57/500 (11%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
I Y+ ++L + + + +P F + LY S+ G + V+A DP+
Sbjct: 336 IVYHHQELNDTDIAKRVRRELRNQSPYFEQA-LYVASVLEEQPPGANVITVRARDPE--- 391
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERR 549
+ V+Y L + + FK++ TG V+ + + E H V A+D P
Sbjct: 392 DSPVVYSLVSLLDSRSQAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGT 451
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVS 607
+L V ++ T P F + V V +G++V IR D + D+
Sbjct: 452 TTLQVNVLDCNDHT-------PTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIE 504
Query: 608 YDLL--------------HGYEEGVP-----------FAVEERSGVITVVDDLSRYNRPM 642
Y + +G EG P F ++ RS I+ L R M
Sbjct: 505 YAITSILGENQEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGM 564
Query: 643 YDFEAVALQ----ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
Y A ++ S T V ++D ND + ++ V+E+
Sbjct: 565 YTIMVTATDMATPQSERKSATTTVLVKILDDNDNYPQFSERTYT---VQVREDQWANENN 621
Query: 699 QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA 758
I H S +R+ I + + G + KPLD E YR+ + A
Sbjct: 622 VIAHIQASDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRA 681
Query: 759 EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
+ + G S + Q+ + + D NDN P F + ++ ++E+ +G I ++A D+D
Sbjct: 682 Q-DGGSPSRSNTTQLLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVR---VQAYDSD 737
Query: 819 EGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL---S 874
EG N+ Y++ M VD TG + +LDRE++ Y +VA D GG+ S
Sbjct: 738 EGANSEITYSIQNRDDGMPLAVDPRTGWI-HTTKALDREEQSRYSFQVVAVD-GGIPPKS 795
Query: 875 SEAELIIMIGDENDNKPEFN 894
+ +I+ I D NDN P F+
Sbjct: 796 ASTSVIVTIQDVNDNDPTFS 815
Score = 88.2 bits (209), Expect = 2e-15
Identities = 110/427 (25%), Positives = 176/427 (41%), Gaps = 43/427 (10%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKK 1047
F I+ G V + + L E+ +RL I A DGG+ + + + ++ V D ND+ P F
Sbjct: 652 FSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQLLVNVLDANDNAPRFYT 711
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
+ + V E+ + +V A D+D G N+ +TY IQ D +P + P TG +
Sbjct: 712 SQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDDGMPLAVDPRTGWIHTTKA 771
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEA 1165
LDRE + +Y VVA D G DVNDN P F ++ +L P
Sbjct: 772 LDREEQSRYSFQVVAVDGG-IPPKSASTSVIVTIQDVNDNDPTFSPKYYEAMLAEDQPPG 830
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQ 1224
++ P + + G T + FA + NG GLI + P K +
Sbjct: 831 TPVTTVTATD----PDEDSRLHYEITAGNTRGR-FAITSQ---NGRGLITIAQPLDYKQE 882
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDK--PVFISRYYELEIEEN--VNAPVELVSLN 1280
+ L ++ + A V + ++ PVF + Y + E+ + V +VS +
Sbjct: 883 RRFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSASVFEDAPIGTTVLVVSAS 942
Query: 1281 LTEHYENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
++ N ++ Y + +E N F I+ + G + DRE Y + V A+
Sbjct: 943 DSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIITNAKLDRESTSGYLLTVTAKDG 1002
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA-IPTTAPF 1397
P D + V + + DVNDN+P F PL A IP A
Sbjct: 1003 G---------NPSLSDTTD--------VEISVTDVNDNAPVF---KVPLYQATIPEDALI 1042
Query: 1398 GYQVMQL 1404
G V+Q+
Sbjct: 1043 GTSVVQI 1049
Score = 87.0 bits (206), Expect = 3e-15
Identities = 118/485 (24%), Positives = 201/485 (41%), Gaps = 71/485 (14%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++P+G I+++ A D D G N +I Y + D + + ++ R G +
Sbjct: 720 ESVPVGYNIVRVQAYDSDEGANSEITYSIQNR---------DDGMPL----AVDPRTGWI 766
Query: 1002 IVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++L E S + + A+DGG + + SV V ++DVND+ P F +Y + E
Sbjct: 767 HTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYEAMLAED 826
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDRETEDK 1115
Q + V ATD D +++ L Y I +T F I+ G ++++ LD + E +
Sbjct: 827 QPPGTPVTTVTATDPD--EDSRLHYEITAGNTRGRFAITSQNGRGLITIAQPLDYKQERR 884
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ LT+ A D+G D N+ +P F E + ++ +
Sbjct: 885 FALTITATDSGQRTDTAIVNINIT---DANNFAPVF----ENAPYSASVFEDAPIGT--T 935
Query: 1176 VMMIPVYKATIEENAPI-----GTTVAKVFANDTDFIGNGNGLILYS--LPQRKNQQNL- 1227
V+++ + + NA I +V + AN+ I G I+ + L + L
Sbjct: 936 VLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIITNAKLDRESTSGYLL 995
Query: 1228 -------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
G PSLS T + ++V DV D + PVF Y+ I E+ +V +
Sbjct: 996 TVTAKDGGNPSLSDTTDVEISVTDVND-----NAPVFKVPLYQATIPEDALIGTSVVQIA 1050
Query: 1281 LTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
T+ R Y L + D D +FV+DP +G + + DRE Y +
Sbjct: 1051 ATDLDMGLNGRVKYALGQKDMD-EGSFVVDPISGVIRTNKGLDRESIPVYHLTA------ 1103
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGY 1399
+A D V+V +R+ DVND+ P F + L +P +P G
Sbjct: 1104 -----------IASDKGTPTMSSSVEVQIRLDDVNDSPPTFASDK--LTLYVPENSPVGS 1150
Query: 1400 QVMQL 1404
V ++
Sbjct: 1151 VVGEI 1155
Score = 85.4 bits (202), Expect = 1e-14
Identities = 72/250 (28%), Positives = 119/250 (47%), Gaps = 20/250 (8%)
Query: 218 IHAIDQDLGVGATLRY----ELISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D+G+ A + Y E ++G + F++++ G++ +LD ++ + +
Sbjct: 939 VSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIITNAKLDRES-----TSGY 993
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+L V A NP + VEI + D+NDN P F+V Y +I E+ G SV+Q+ ATD
Sbjct: 994 LLTVTAKDGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIPEDALIGTSVVQIAATD 1053
Query: 333 KDQGENGEFTY---QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D G NG Y Q D +G+F +DP SG +R LDRE+ + A +
Sbjct: 1054 LDMGLNGRVKYALGQKDMDEGSFVVDPISG--VIRTNKGLDRESIPVYHLTAIASDKGTP 1111
Query: 390 VVGTFADSQ-RIAKWRRQPLETNAPLEKTTYVFPDK--VGTKTENIEYYDEQLMSFVNVE 446
+ + + Q R+ P T A + T YV P+ VG+ I +D V
Sbjct: 1112 TMSSSVEVQIRLDDVNDSP-PTFASDKLTLYV-PENSPVGSVVGEIYAHDPDEGVNAIVH 1169
Query: 447 VTLLDANDNN 456
+++ +D+N
Sbjct: 1170 YSIIGGDDSN 1179
Score = 80.2 bits (189), Expect = 4e-13
Identities = 113/495 (22%), Positives = 193/495 (38%), Gaps = 66/495 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK-------------LSADAL 986
+ E + +G+T+I + A D D G N I Y S + + + D+
Sbjct: 477 VREGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQEQSGTAANGSNEGNPVEGDSN 536
Query: 987 EVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-----GGNLNDNISVRVFVKDVN 1039
+ F I+ R + +L E + + ++A D + +V V + D N
Sbjct: 537 GSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMATPQSERKSATTTVLVKILDDN 596
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRR--VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
D++P F + Y V E Q+ V+ + A+DAD G NA + Y I +T F I
Sbjct: 597 DNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYAIIGGNTQSQFSIDS 656
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
++G +S+ LD E Y L + A+D G D NDN+P+FY
Sbjct: 657 MSGDVSLVKPLDYENVRSYRLVIRAQDGG-SPSRSNTTQLLVNVLDANDNAPRFYTS--- 712
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+ EA S +++ + Y + N+ I ++ + G I +
Sbjct: 713 ---QFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDDGMPLAVDPRTGWIHTT 769
Query: 1218 LPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
+ +Q+ G+P S++ ++VT+ DV D + P F +YYE +
Sbjct: 770 KALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVND-----NDPTFSPKYYEAMLA 824
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
E+ + ++ T+ E+ ++ Y I N R F I +NG
Sbjct: 825 EDQPPGTPVTTVTATDPDEDSRLHYEITAGN---TRGRFAITSQNGR------------- 868
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPL 1387
+I A+ Y +E + A D G V + I D N+ +P F N P
Sbjct: 869 --GLITIAQPLDYKQERRFALTITATD--SGQRTDTAIVNINITDANNFAPVFENA--PY 922
Query: 1388 VTAIPTTAPFGYQVM 1402
++ AP G V+
Sbjct: 923 SASVFEDAPIGTTVL 937
Score = 70.1 bits (164), Expect = 4e-10
Identities = 103/421 (24%), Positives = 166/421 (39%), Gaps = 34/421 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSLTIPLT 133
SA +V V I D NDN P F + Y V V E E I I A G + I
Sbjct: 583 SATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYA 642
Query: 134 VPRGLTIFK-DIRAFDRD----KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+ G T + I + D KP + Y +V DG S LL VL
Sbjct: 643 IIGGNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDG--GSPSRSNTTQLLVNVL 700
Query: 189 DYDAG-----DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
D + +FQ ++ S + + + A D D G + + Y + + +D
Sbjct: 701 DANDNAPRFYTSQFQEAVLESVPVGYNIVR----VQAYDSDEGANSEITYSIQNRDDGMP 756
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
++D G + K LD + + + + QV A P K+A V + + D+NDN
Sbjct: 757 LAVDPRTGWIHTTKALDREEQ-----SRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDND 811
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P F +Y + E+ P G V V ATD D+ + + +G F+I ++G +
Sbjct: 812 PTFSPKYYEAMLAEDQPPGTPVTTVTATDPDEDSRLHYEITAGNTRGRFAITSQNGRGLI 871
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPD 423
LD + + + A ++ + P+ NAP + VF D
Sbjct: 872 TIAQPLDYKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSAS--VFED 929
Query: 424 -KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
+GT + D + +N ++T L ND + + +N F++ NA+ G +I
Sbjct: 930 APIGTTVLVVSASDSDV--GINAQITYL-LNDESVNGLGAN-EPFTI--NAQTGAIITNA 983
Query: 483 K 483
K
Sbjct: 984 K 984
Score = 62.9 bits (146), Expect = 7e-08
Identities = 63/244 (25%), Positives = 109/244 (44%), Gaps = 16/244 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L +VE+++ D NDN PVF VP LY+ ++ +A +GT + ++ A D D+G NG V Y
Sbjct: 1007 LSDTTDVEISVTDVNDNAPVFKVP--LYQATIPEDALIGTSVVQIAATDLDMGLNGRVKY 1064
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
L + F ++P +G + + L+ R ++ V A+ + V +
Sbjct: 1065 ALGQKD--MDEGSFVVDPISGVIRTNKG--LD-RESIPVYHLTAIASDKGTPTMSSSVEV 1119
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEE 616
++ + P P F +V N +G+ VG+I +D E N + + + G ++
Sbjct: 1120 QIRLDDVNDSP--PTFASDKLTLYVPENSPVGSVVGEIYAHDPDEGVNAIVHYSIIGGDD 1177
Query: 617 GVPFAVEERSG----VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
F++ R G + + +L Y P FE + + L + V DVND
Sbjct: 1178 SNSFSLVTRPGSDRAQLLTMTELD-YESPRKRFELIIRAASPPLRNDVYVEILVTDVNDN 1236
Query: 673 RGVL 676
VL
Sbjct: 1237 APVL 1240
Score = 58.8 bits (136), Expect = 1e-06
Identities = 96/392 (24%), Positives = 148/392 (37%), Gaps = 69/392 (17%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI----- 1084
+++V V D NDH P F+ ++ V E + + ATD D G+NA++ Y I
Sbjct: 453 TLQVNVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILG 512
Query: 1085 ----------------QPSDTD-----LPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
P + D F I + +S LDRE Y + V A
Sbjct: 513 ENQEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTAT 572
Query: 1124 DNGX--XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPV 1181
D D NDN P+ F E D+ +N N + I
Sbjct: 573 DMATPQSERKSATTTVLVKILDDNDNYPQ---FSERTYTVQVREDQWANEN-NVIAHIQA 628
Query: 1182 YKATIEENAPI------GTTVAKV----FANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
A NA I G T ++ + D + + + S Q+ G PS
Sbjct: 629 SDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPS 688
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFK 1289
S+T L+V V D D + P F + ++ + E+V +V + + E N +
Sbjct: 689 RSNTTQLLVNVLDAND-----NAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSE 743
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIY 1349
+ Y I N +D +DPR G ++ ++ DRE E+ +YS ++
Sbjct: 744 ITYSIQNRDD---GMPLAVDPRTGWIHTTKALDRE-----------EQSRYSFQV----- 784
Query: 1350 PVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
VA D V+V I+DVNDN P F+
Sbjct: 785 -VAVDGGIPPKSASTSVIVTIQDVNDNDPTFS 815
Score = 49.2 bits (112), Expect = 9e-04
Identities = 44/174 (25%), Positives = 77/174 (44%), Gaps = 17/174 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKRYFVIN 995
+PEN P+G+ + ++ A D D G+N + Y +S + ++ +D ++ ++
Sbjct: 1142 VPENSPVGSVVGEIYAHDPDEGVNAIVHYSIIGGDDSNSFSLVTRPGSDRAQLLTMTELD 1201
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
P F L I A ND + V + V DVND+ PV + FN
Sbjct: 1202 YES----------PRKRFELIIRAASPPLRND-VYVEILVTDVNDNAPVLRDFQVIFNNF 1250
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ V+G++ A DAD LTY I + ++ TG L+++ +L+
Sbjct: 1251 RDCFPSGVIGRIPAFDADV--TDKLTYRILSGNNANLLRLNSSTGGLTLSPQLN 1302
Score = 48.8 bits (111), Expect = 0.001
Identities = 55/221 (24%), Positives = 92/221 (41%), Gaps = 17/221 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ S V V++ L D ND+ P F L + + N+ VG+V+G++ A DPD G N +V Y
Sbjct: 1113 MSSSVEVQIRLDDVNDSPPTFASDKLTLY-VPENSPVGSVVGEIYAHDPDEGVNAIVHYS 1171
Query: 499 L----QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
+ S +T P T++ + R L + A+ P
Sbjct: 1172 IIGGDDSNSFSLVTRPGSDRAQLLTMTELDYESPRKRFELIIRAASPPLRND------VY 1225
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
V I VT N P + DF F G+ +G+I DA + ++Y +L G
Sbjct: 1226 VEILVT-DVNDNAPVLRDFQVIFNNFRDCFPSGV---IGRIPAFDADVTDKLTYRILSGN 1281
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
+ + +G +T+ L+ N P + V++ + N
Sbjct: 1282 NANL-LRLNSSTGGLTLSPQLNT-NVPKFATMEVSVTDGIN 1320
Score = 48.0 bits (109), Expect = 0.002
Identities = 69/306 (22%), Positives = 118/306 (38%), Gaps = 20/306 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S V + + DVNDN P+F Y T+ E G + L +
Sbjct: 1003 GNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIPEDALIGTSVVQIAATDLDMGLNGRV 1062
Query: 133 T-------VPRGLTIFKDIRAFDRDKPNTPNSD--VHYSIVSGNDDGHFALESSHKPVLL 183
+ G + I R V++ +D G + SS + +
Sbjct: 1063 KYALGQKDMDEGSFVVDPISGVIRTNKGLDRESIPVYHLTAIASDKGTPTMSSSVEVQIR 1122
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
L V D +L + ++ I+A D D GV A + Y +I G+D
Sbjct: 1123 LDDVNDSPPTFASDKLTLYVPENSPVGSVV--GEIYAHDPDEGVNAIVHYSIIGGDDSNS 1180
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FSL + GS + + ++ F L ++A+ + PL+ VEI + D+NDN
Sbjct: 1181 FSLVTRPGSDRAQLLTMTELDYESPRKRFELIIRAA--SPPLRN-DVYVEILVTDVNDNA 1237
Query: 304 P---EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
P +F+V F N + P+G + ++ A D D + + + ++ +G
Sbjct: 1238 PVLRDFQVIFNNFR--DCFPSGV-IGRIPAFDADVTDKLTYRILSGNNANLLRLNSSTGG 1294
Query: 361 LTVRNQ 366
LT+ Q
Sbjct: 1295 LTLSPQ 1300
Score = 39.5 bits (88), Expect = 0.69
Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 1/129 (0%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
LND + +++ + P F++ Y +V E Q + V A D + +
Sbjct: 343 LNDTDIAKRVRRELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPEDSPVVYSLVSL 402
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
S + F++ TGV++ + LDRE D + V+A D+ D
Sbjct: 403 LDSRSQAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDD-SFPPRSGTTTLQVNVLDC 461
Query: 1145 NDNSPKFYA 1153
ND++P F A
Sbjct: 462 NDHTPTFEA 470
>UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42;
Arthropoda|Rep: Neural-cadherin precursor - Drosophila
melanogaster (Fruit fly)
Length = 3097
Score = 148 bits (358), Expect = 1e-33
Identities = 205/739 (27%), Positives = 309/739 (41%), Gaps = 94/739 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN PVF + Y ++ A G+ + KV A D D G NG V Y + + N
Sbjct: 954 VVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPN 1013
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS-LAVVTIEVTRGT 563
T F ++ TG VS + EG FV + + + + + T+E+T
Sbjct: 1014 QKGTK-FTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEIT--D 1070
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG--VP 619
+ P P F Y V + IGT++ ++ +D N+ + Y L +
Sbjct: 1071 VNDNP--PLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEY 1128
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLK 678
F ++ SG I + L +R Y EA+A + LS + VVD + V
Sbjct: 1129 FEIQAESGWIVLKKPL---DRETYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWDH 1185
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDVTDDIAI----- 732
+ PI +VKEN G++ SS I GN T R + +
Sbjct: 1186 TVYGPI--YVKENMPVG--GKVVSIKASSGIEGNPTVFYRLMPGSTAQTNKFHTFYLQQR 1241
Query: 733 AEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++G I PLD E Y +T+ E N G A V I +ED ND P+F
Sbjct: 1242 PDNGDTWADIKVNHPLDYESIKEYNLTIRVE-NNGAQQLASEATVYIMLEDVNDEIPLFT 1300
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEMFDVDENTGV 845
E ++E IGT++ N I D N ++ Y + EGKE F+++ +G
Sbjct: 1301 EREQET-VLEGEPIGTKVTQVNAIDK-DGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGE 1358
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+ F DREKK Y L + ARD G S+ N N P N + + +RI
Sbjct: 1359 I-FTKTVFDREKKGAYALEVEARD-GAPSARP---------NSNGP--NSVTKF--IRIG 1403
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
K + F K+ + +VD EN I T++ + A D D + +
Sbjct: 1404 IADKNDNPPYFD------KSLYEAEVD---------ENEDIQHTVLTVTAKDHDE--SSR 1446
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNL 1025
IRYE S + F + G + VA +L E+ R + NL
Sbjct: 1447 IRYEITSG-------------NIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDNL 1493
Query: 1026 NDNIS-VRVFVKDVNDHFPVFKKTWYNFNV---EEAQYTRRVLGKVDATDADFGQNANLT 1081
+N + V + VKDVND+ PVF++ Y + ++ +RVL +V ATD D + N+
Sbjct: 1494 KENYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVL-QVTATDGDKDRPQNIV 1552
Query: 1082 YFI--QPSDTDLP----FEISPLTGVLSVNGELDRETED---KYILTVVARDNGXXXXXX 1132
YF+ Q D D P F+I+ TG + V LDR+ + ++ TV A+D G
Sbjct: 1553 YFLTGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEG-GEGLV 1611
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D+NDN+P F
Sbjct: 1612 GYADVQVNLKDINDNAPIF 1630
Score = 143 bits (347), Expect = 3e-32
Identities = 131/481 (27%), Positives = 210/481 (43%), Gaps = 31/481 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMV 495
+QL S V + L D ND P+F + ++ +GT + +V A+D D N V
Sbjct: 1277 QQLASEATVYIMLEDVNDEIPLFTERE--QETVLEGEPIGTKVTQVNAIDKDGTFPNNQV 1334
Query: 496 LYDLQRTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASD--QPANPSERRYS 551
Y + + F+IN +G + +G +AL VEA D A P+ +
Sbjct: 1335 YYYIVDSPRNEGKEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPN 1394
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
I + K + P P F + YE V N I +V + D E + + Y++
Sbjct: 1395 SVTKFIRIGIADKNDNP--PYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEIT 1452
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G G FAV+ +G I V L R Y+ +A +N + T +HV DVND
Sbjct: 1453 SGNIGGA-FAVKNMTGAIYVAGALDYETRRRYELR-LAASDNLKENYTT-VIIHVKDVND 1509
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
V + + I + + + Q+ T+ + N+ + + Q D+ A
Sbjct: 1510 NPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDK---DRPQNIVYFLTGQGIDPDNPA 1566
Query: 732 IAE------DGTIFTQKPLDREK---RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
++ G IF KPLDR++ R +R TV A+ ++G G V + ++D ND
Sbjct: 1567 NSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQ-DEGGEGLVGYADVQVNLKDIND 1625
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------GKEM 836
N P+F Y G + EN G + + D +EG+NA +Y++ G +
Sbjct: 1626 NAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPI 1685
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F+++ +TGV+K LDRE+ Y + +VA D GGL I + D ND P+F +
Sbjct: 1686 FEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDINDMPPQFTKD 1745
Query: 897 E 897
E
Sbjct: 1746 E 1746
Score = 113 bits (272), Expect = 4e-23
Identities = 123/481 (25%), Positives = 204/481 (42%), Gaps = 40/481 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L + V + D NDN P+F Y ++K +A +GT I +V A D D NG +
Sbjct: 1055 DPSLEGVCSFTVEITDVNDNPPLF-DRQKYVENVKQDASIGTNILRVSASDEDADNNGAI 1113
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+Y L N F+I +G + V + P+ + L A D+ P R V
Sbjct: 1114 VYSLTAPFNPNDLEYFEIQAESGWI-VLKKPLDRETYKLEAMAQDKGYPPLSR-----TV 1167
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGY 614
+++ + N P + D +V N+ +G V I+ + E N V Y L+ G
Sbjct: 1168 EVQIDVVDRANNPPVWDHT-VYGPIYVKENMPVGGKVVSIKASSGIEGNPTVFYRLMPGS 1226
Query: 615 EEGV----PFAVEERSGVITVVDDLSRYNRPMYDFEA-------VALQENANLSIVTNAT 663
F +++R D+ + N P+ D+E+ + ++ N + + AT
Sbjct: 1227 TAQTNKFHTFYLQQRPDNGDTWADI-KVNHPL-DYESIKEYNLTIRVENNGAQQLASEAT 1284
Query: 664 VHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
V+++ DVNDE + + ++ + G + Q+ + + N + +
Sbjct: 1285 VYIMLEDVNDEIPLFTEREQETVL---EGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDS 1341
Query: 722 NQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFN--KGVISGAGIYQVT---- 774
+ + + I + G IFT+ DREK+ Y + V A + G VT
Sbjct: 1342 PRNEGKEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTKFIR 1401
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
I I D+NDNPP F+ + YE + EN I + + A D DE + + T G
Sbjct: 1402 IGIADKNDNPPYFDKSLYEAEVDENEDIQHTVL---TVTAKDHDESSRIRYEIT-SGNIG 1457
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
F V TG + ++ +LD E + Y+L L A D + +II + D NDN P F
Sbjct: 1458 GAFAVKNMTGAI-YVAGALDYETRRRYELRLAASD-NLKENYTTVIIHVKDVNDNPPVFE 1515
Query: 895 Q 895
+
Sbjct: 1516 R 1516
Score = 108 bits (260), Expect = 1e-21
Identities = 123/470 (26%), Positives = 203/470 (43%), Gaps = 49/470 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V++ + + D NDN P F + ++ + +GT I +VKA+D D G N + Y
Sbjct: 740 VDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEY----- 794
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALF---VEASDQPANPSERRYSLAVVTIEV 559
L F ++ N G + + + +A + V A D+ P V T+ V
Sbjct: 795 --LVSDDHFAVDSN-GIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKS-----GVATVRV 846
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
TK + P F Y V N G T V + +D + ++V + + G
Sbjct: 847 Y--TKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDK-DGDNVRFGFVGGGTSSGQ 903
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-----NANLSIVTNATVHVV---DVND 671
F +E+ +GVI + + ++ Y+ A+ + N + +I T+ V VV DVND
Sbjct: 904 FVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVND 963
Query: 672 ERGVLLK-GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ--QDVTD 728
+ V + P + N G+ + ++ T+ G V++ I Q Q T
Sbjct: 964 NKPVFKDCSTYYPKVEEGAPN--GSPVIKVVATDEDK---GVNGQVKYSIVQQPNQKGTK 1018
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
E G + T K DRE D ++V + ++G S G+ T+ I D NDNPP+F
Sbjct: 1019 FTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEITDVNDNPPLF 1078
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENT 843
+ Y + +++ IGT I + A+D D N +Y+L E F++ +
Sbjct: 1079 DRQKYVENVKQDASIGTNILR---VSASDEDADNNGAIVYSLTAPFNPNDLEYFEIQAES 1135
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
G + + LDRE YKL +A+D G LS E+ I + D +N P
Sbjct: 1136 GWI-VLKKPLDRE---TYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPP 1181
Score = 107 bits (258), Expect = 2e-21
Identities = 115/478 (24%), Positives = 202/478 (42%), Gaps = 46/478 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLG 490
I+Y D Q V + + D ND P F+ L + ++ NA T + ++A DPD
Sbjct: 521 IKYTDNQ-----RVIILVKDVNDEPPYFINRPLPMQAVVQLNAPPNTPVFTLQARDPDTD 575
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSER 548
N RT F+++ +G V + + L+ + L+V+A DQ +R
Sbjct: 576 HNIHYFIVRDRTGGR-----FEVDERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGKVDDR 630
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
R+ T E G K P F YE + N + + I+ +F ++ Y
Sbjct: 631 RFQ---STPEERLSIVGGK-RAPQFYMPSYEAEIPENQKKDSDIISIKAK-SFADREIRY 685
Query: 609 DLLHGYEEGVPFAVEERSGVITVVD--DLSRYNRP-MYDFEAVALQENANLSIVTNATVH 665
L + F + SG++ + D +P +Y A +++ S + T+
Sbjct: 686 TLKAQGQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVTATEDSGGFSTSVDLTIR 745
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V DVND + +V E+ G +I ++ M S G+ + +L+++
Sbjct: 746 VTDVNDNAPKFELPDYQ--AHNVDEDIPLGTSILRV--KAMDSDSGS-NAEIEYLVSD-- 798
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
D A+ +G I K LD + + Y ++ +KG +G+ V +Y +++ND
Sbjct: 799 ---DHFAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKNDEE 855
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P F Y + EN+ T + + A+D D G N F + G F +++ TG
Sbjct: 856 PKFSQQVYTPNVDENAGPNTLV---TTVVASDKD-GDNVRFGFVGGGTSSGQFVIEDITG 911
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGL---------SSEAELIIMIGDENDNKPEF 893
V++ ++ +K Y+L++ A D G +S A +++ I D NDNKP F
Sbjct: 912 VIRLHNKAISLDKD-KYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVF 968
Score = 86.2 bits (204), Expect = 6e-15
Identities = 226/1005 (22%), Positives = 397/1005 (39%), Gaps = 157/1005 (15%)
Query: 425 VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKA 484
V + +N + D + S ++++ ++PS YE + N K + I +KA
Sbjct: 618 VKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPS--YEAEIPENQKKDSDIISIKA 675
Query: 485 VDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPAN 544
+ + Y L+ T F I P +G V +A+ E V + A
Sbjct: 676 KS---FADREIRYTLKAQGQGAGT--FNIGPTSGIVKLAKELDFEDLRQPHVYSLIVTAT 730
Query: 545 PSERRYSLAV-VTIEVTRGTKGNKP--DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF 601
+S +V +TI VT N P ++PD+ V ++ +GTS+ +++ D+
Sbjct: 731 EDSGGFSTSVDLTIRVT-DVNDNAPKFELPDYQAHN----VDEDIPLGTSILRVKAMDSD 785
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVT 660
++ + L + FAV+ ++ + N Y+F A + S V
Sbjct: 786 SGSNAEIEYLVSDDH---FAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVA 842
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSS------IYGNGT 713
V+ + NDE + ++P +V EN+ + + ++ G GT
Sbjct: 843 TVRVYTKNKNDEEPKFSQQVYTP---NVDENAGPNTLVTTVVASDKDGDNVRFGFVGGGT 899
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ- 772
+ +F+I +D+T I + LD++K ++ +T + + + V I+
Sbjct: 900 SSGQFVI---EDITGVIRLHNKAI-----SLDKDKYEL-NVTAMDDGSCCVNGDQTIHTS 950
Query: 773 ---VTIYIEDENDNPPVFEH-ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
V ++I D NDN PVF+ +TY + E + G+ + + ATD D+G N
Sbjct: 951 TAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIK---VVATDEDKGVN------ 1001
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEND 888
G+ K N KF D +TG +S+ + D
Sbjct: 1002 --GQVKYSIVQQPNQKGTKFTVDE----------------ETGEVSTNK-----VFDREG 1038
Query: 889 NKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGT 948
+ +F + K + L G FT+ E+ N D+ + + ++ IGT
Sbjct: 1039 DDGKF--VSVTVKATDQGDPSLEGVCSFTV-EITDVNDNPPLFDRQKYVENVKQDASIGT 1095
Query: 949 TIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP 1008
I++++A D D+ NG I Y + P+ L YF I G +++ + L
Sbjct: 1096 NILRVSASDEDADNNGAIVYSLTAP--FNPNDLE--------YFEIQAESGWIVLKKPLD 1145
Query: 1009 PESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN-FNVEEAQYTRRVLG 1065
E+ ++L A D G L+ + V++ V D ++ PV+ T Y V+E V G
Sbjct: 1146 RET-YKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWDHTVYGPIYVKE---NMPVGG 1201
Query: 1066 KVDATDADFGQNANLTYF--IQPSDT-------DLPFEISPLTGV----LSVNGELDRET 1112
KV + A G N T F + P T + P G + VN LD E+
Sbjct: 1202 KVVSIKASSGIEGNPTVFYRLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYES 1261
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE--LLEWKHPEADELSN 1170
+Y LT+ +NG DVND P F ++ +LE + P +++
Sbjct: 1262 IKEYNLTIRVENNGAQQLASEATVYIMLE-DVNDEIPLFTEREQETVLEGE-PIGTKVTQ 1319
Query: 1171 HN-FESVMMIP---VYKATIE-------ENAPIGTTVAKVFANDTDFIGNGNGLILYSLP 1219
N + P VY ++ E I ++F T F G +
Sbjct: 1320 VNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGEIFTK-TVFDREKKGAYALEVE 1378
Query: 1220 QRKN----QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
R + N P+ S T + + +AD D + P F YE E++EN +
Sbjct: 1379 ARDGAPSARPNSNGPN-SVTKFIRIGIADKND-----NPPYFDKSLYEAEVDENEDIQHT 1432
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++++ +H E+ ++RY I + N I F + G +Y+ + D E + YE+ + A
Sbjct: 1433 VLTVTAKDHDESSRIRYEITSGN---IGGAFAVKNMTGAIYVAGALDYETRRRYELRLAA 1489
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
++++ E T V++ +KDVNDN P F
Sbjct: 1490 ----------------SDNLKENYTT----VIIHVKDVNDNPPVF 1514
Score = 81.8 bits (193), Expect = 1e-13
Identities = 109/419 (26%), Positives = 172/419 (41%), Gaps = 46/419 (10%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVR-------VFVKDVNDHFPVFKK-TWYNFNVEEAQY 1059
+ ++ LN++A+D G+ +N + ++ VF+ DVND+ PVFK + Y VEE
Sbjct: 924 KDKYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAP 983
Query: 1060 TRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETED-KY 1116
+ KV ATD D G N + Y I QP+ F + TG +S N DRE +D K+
Sbjct: 984 NGSPVIKVVATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKF 1043
Query: 1117 I-LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ +TV A D G DVNDN P FD ++ + D N
Sbjct: 1044 VSVTVKATDQG-DPSLEGVCSFTVEITDVNDNPP---LFDRQKYVENVKQDASIGTN--- 1096
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVF-ANDTDF--IGNGNGLILYSLPQRKN-------QQ 1225
++ + + N I ++ F ND ++ I +G I+ P + Q
Sbjct: 1097 ILRVSASDEDADNNGAIVYSLTAPFNPNDLEYFEIQAESGWIVLKKPLDRETYKLEAMAQ 1156
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+ G P LS T + + V D + + D V Y + ++EN+ ++VS+ +
Sbjct: 1157 DKGYPPLSRTVEVQIDVVDRANNPPVWDHTV----YGPIYVKENMPVGGKVVSIKASSGI 1212
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
E +Y L T F T YL + PD DT+ I Y
Sbjct: 1213 EGNPTVFYRLMPGSTAQTNKF------HTFYLQQRPDN--GDTWADIKVNHPLDYESIKE 1264
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ + E+ + V + ++DVND P FT + V P G +V Q+
Sbjct: 1265 YNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTEREQETVL---EGEPIGTKVTQV 1320
Score = 79.8 bits (188), Expect = 5e-13
Identities = 122/489 (24%), Positives = 209/489 (42%), Gaps = 54/489 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ V + + D NDN PVF P+ + + + + + + +V A D D + ++Y L
Sbjct: 1496 NYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFL 1555
Query: 500 QRTS---NLTITSPFKINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYS 551
+ S F IN TG + V + P + V A D+ E
Sbjct: 1556 TGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGG---EGLVG 1612
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-L 610
A V + + K + P F Y V N G V + D + N+ S L
Sbjct: 1613 YADVQVNL----KDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARL 1668
Query: 611 LHGYEEGV-------P-FAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
++ E+ V P F +E +GVI T V L R P Y + VA+ + L
Sbjct: 1669 VYSIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAM-DGGGLKGTGT 1727
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LI 720
A++ V D+ND K F + + G A+ ++ ++ + T ++ +I
Sbjct: 1728 ASIRVKDINDMPPQFTKDEW----FTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVI 1783
Query: 721 ANQQDVTDDIAIAED----GTIFTQKPLDREKR---DVYRMTVIAEFNKGVISGAGIYQV 773
N D + + G++ +PLD E + + +R + +KG + Y V
Sbjct: 1784 DNSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVN-DKGEDNDNDKYHV 1842
Query: 774 T-----IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+ + D NDN P FE A E + E++K+GTE++ KATD D+G + Y+
Sbjct: 1843 AYSWVVVKLRDINDNKPHFERANVEVSVFEDTKVGTELEK---FKATDPDQGGKSKVSYS 1899
Query: 829 L--FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIG 884
+ + + F +++N V I SLDRE +++ ++A D G ++ A L +++
Sbjct: 1900 IDRSSDRQRQFAINQNGSVT--IQRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQ 1957
Query: 885 DENDNKPEF 893
D NDN P+F
Sbjct: 1958 DINDNAPKF 1966
Score = 78.2 bits (184), Expect = 2e-12
Identities = 175/744 (23%), Positives = 302/744 (40%), Gaps = 105/744 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + D NDN P F S LYE + N + + V A D D ++ + Y++ TS
Sbjct: 1400 IRIGIADKNDNPPYFDKS-LYEAEVDENEDIQHTVLTVTAKDHD--ESSRIRYEI--TSG 1454
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
I F + TG + VA + E R + L + ASD + Y+ ++ ++
Sbjct: 1455 -NIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDN----LKENYTTVIIHVKDVN- 1508
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE---QNDVSYDLLHGYEEGVP 619
+ P + + + + + V Q+ D + QN V + G + P
Sbjct: 1509 ---DNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNP 1565
Query: 620 ----FAVEERSGVITVVDDLSR---YNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
F + +G I V+ L R RP + F A E L + V++ D+ND
Sbjct: 1566 ANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDIND 1625
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG--NGTGNVRFLIANQQDVTDD 729
+ +G + +V EN G A G + T + Y N N R + + +++V ++
Sbjct: 1626 NAPIFPQGVY---FGNVTEN--GTA-GMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEE 1679
Query: 730 ------IAIAED-GTIFTQKP-LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
I D G I T LDRE+ Y + V+A + G + G G +I ++D N
Sbjct: 1680 ETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVA-MDGGGLKGTGT--ASIRVKDIN 1736
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
D PP F E F + GT + I+ T DE F Y + +
Sbjct: 1737 DMPPQFTKD--EWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVI----------D 1784
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
N+G + D K ++V + G S + + D+ + +I+ N K
Sbjct: 1785 NSG---YGAD----------KFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDK 1831
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
+ K + + +++++ N ++ + E+ +GT + K A D D G
Sbjct: 1832 GEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQG 1891
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISA 1019
++ Y + S+D +R F IN+ +G V + RSL E ++ I A
Sbjct: 1892 GKSKVSYSIDR---------SSDR---QRQFAINQ-NGSVTIQRSLDREVVPRHQVKILA 1938
Query: 1020 LDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
+D G+ ++ V V+D+ND+ P F K Y + E R+V+ ++ ATD D
Sbjct: 1939 IDDGSPPKTATATLTVIVQDINDNAPKFLKD-YRPVLPEHVPPRKVV-EILATDDDDRSK 1996
Query: 1078 AN---LTYFIQPSDTDL---PFEISP----LTG----VLSVNGELDRETEDKYILTVVAR 1123
+N + + PS D+ F++ G V+S DRE + +Y++ +V +
Sbjct: 1997 SNGPPFQFRLDPSADDIIRASFKVEQDQKGANGDGMAVISSLRSFDREQQKEYMIPIVIK 2056
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDN 1147
D+G DVNDN
Sbjct: 2057 DHG-SPAMTGTSTLTVIIGDVNDN 2079
Score = 72.5 bits (170), Expect = 8e-11
Identities = 116/432 (26%), Positives = 178/432 (41%), Gaps = 62/432 (14%)
Query: 992 FVINERHGHVIVARSLPPES-----EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPV 1044
F IN G + V + L + ++R + A D G L V+V +KD+ND+ P+
Sbjct: 1570 FDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPI 1629
Query: 1045 FKKTWYNFNVEE---AQYTRRVLGKVDATDADFGQNANLTYFIQPS----DTDLP-FEIS 1096
F + Y NV E A + VD D + G NA L Y I+ + +T P FEI
Sbjct: 1630 FPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIE 1689
Query: 1097 PLTGVL-SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA-- 1153
P TGV+ + LDRE Y + VVA D G D+ND P+F
Sbjct: 1690 PDTGVIKTAVCCLDRERTPDYSIQVVAMDGG---GLKGTGTASIRVKDINDMPPQFTKDE 1746
Query: 1154 -FDELLEWKH---PEA--------DELSNHNFE-SVMMIPVY---KATIEENAPIGTTVA 1197
F E+ E PE DE + F+ V+ Y K T+ N GT
Sbjct: 1747 WFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGADKFTMVRNND-GTGSL 1805
Query: 1198 KVFAN-DTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
K+ D + NG K + N + + ++V + D+ D +KP
Sbjct: 1806 KIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDIND-----NKPH 1860
Query: 1257 FISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
F E+ + E+ EL T+ + K + + +D +R F I+ +NG++
Sbjct: 1861 FERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAIN-QNGSVT 1919
Query: 1317 LVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDN 1376
+ RS DREV ++V + A +D T V+ ++D+NDN
Sbjct: 1920 IQRSLDREVVPRHQVKILA----------------IDDGSPPKTATATLTVI-VQDINDN 1962
Query: 1377 SPKFTNGNRPLV 1388
+PKF RP++
Sbjct: 1963 APKFLKDYRPVL 1974
Score = 67.3 bits (157), Expect = 3e-09
Identities = 86/332 (25%), Positives = 141/332 (42%), Gaps = 25/332 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHV-TVDELTPTGEKAFIF--LIAPIGPSLTIPLTV 134
S + +T+ + DVNDN P F Y VDE P G + + G + I V
Sbjct: 737 STSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLV 796
Query: 135 PRG-LTIFKDIRAFDRDKPNTPNSDVHYS-IVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+ + + + + N++ +Y IV+ D G +S V + K + D
Sbjct: 797 SDDHFAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGE-PPKSGVATVRVYTKNKN-DE 854
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNG 251
K Q V + + A D+D G +R+ + G F ++ + G
Sbjct: 855 EPKFSQQVYTPNVDENAGPNTLVTTVVASDKD---GDNVRFGFVGGGTSSGQFVIEDITG 911
Query: 252 SLFLE-KELDLDAEHNLQANTFVLQVQASQLNNP--LKTAQARVEIELLDLNDNLPEF-E 307
+ L K + LD + + N + + +N + T+ A V + + D+NDN P F +
Sbjct: 912 VIRLHNKAISLDKD-KYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKD 970
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY---QLDDPKGA-FSIDPRSGWLTV 363
Y + E PNG V++V+ATD+D+G NG+ Y Q + KG F++D +G V
Sbjct: 971 CSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETG--EV 1028
Query: 364 RNQTVLDREAHSSLRMKVYAKET---NPSVVG 392
V DRE + V K T +PS+ G
Sbjct: 1029 STNKVFDREGDDGKFVSVTVKATDQGDPSLEG 1060
Score = 66.9 bits (156), Expect = 4e-09
Identities = 43/162 (26%), Positives = 77/162 (47%), Gaps = 12/162 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRK--LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
A D+D GV ++Y ++ ++K F++D G + K D + + + + V+
Sbjct: 993 ATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVS---VTVK 1049
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +P +E+ D+NDN P F+ Y ++ ++ G ++L+V A+D+D
Sbjct: 1050 ATDQGDPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADN 1109
Query: 338 NGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAH 374
NG Y L P F I SGW+ ++ LDRE +
Sbjct: 1110 NGAIVYSLTAPFNPNDLEYFEIQAESGWIVLKKP--LDRETY 1149
Score = 66.1 bits (154), Expect = 7e-09
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 7/156 (4%)
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
QPL+ L+ + F +V K E+ + D+ +++ V V L D NDN P F +N+
Sbjct: 1809 QPLDYEDQLQSNGFRFRIQVNDKGEDNDN-DKYHVAYSWVVVKLRDINDNKPHFERANV- 1866
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
E S+ + KVGT + K KA DPD G V Y + R+S+ F IN N G+V++ S
Sbjct: 1867 EVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDR--QRQFAINQN-GSVTIQRS 1923
Query: 526 PILE--GRHALFVEASDQPANPSERRYSLAVVTIEV 559
E RH + + A D + P +L V+ ++
Sbjct: 1924 LDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDI 1959
Score = 63.3 bits (147), Expect = 5e-08
Identities = 45/138 (32%), Positives = 73/138 (52%), Gaps = 9/138 (6%)
Query: 231 LRYEL-ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+RY L G F++ +G + L KELD E Q + + L V A++ + T+
Sbjct: 683 IRYTLKAQGQGAGTFNIGPTSGIVKLAKELDF--EDLRQPHVYSLIVTATEDSGGFSTS- 739
Query: 290 ARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
+ I + D+NDN P+FE+ D+ ++ E++P G S+L+V A D D G N E Y + D
Sbjct: 740 VDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVSDD 799
Query: 349 KGAFSIDPRSGWLTVRNQ 366
F++D S + V N+
Sbjct: 800 H--FAVD--SNGIIVNNK 813
Score = 58.8 bits (136), Expect = 1e-06
Identities = 42/131 (32%), Positives = 69/131 (52%), Gaps = 11/131 (8%)
Query: 261 LDAEHNLQANTFVLQVQASQL-----NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
LD E LQ+N F ++Q + N+ A + V ++L D+NDN P FE +S+
Sbjct: 1811 LDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSV 1870
Query: 316 VENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDRE 372
E+ G + + ATD DQG + +Y +D D + F+I+ ++G +T+ Q LDRE
Sbjct: 1871 FEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAIN-QNGSVTI--QRSLDRE 1927
Query: 373 AHSSLRMKVYA 383
++K+ A
Sbjct: 1928 VVPRHQVKILA 1938
Score = 55.6 bits (128), Expect = 1e-05
Identities = 80/302 (26%), Positives = 128/302 (42%), Gaps = 45/302 (14%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
+D + +RYE+ SGN F++ ++ G++++ LD + + L++ AS
Sbjct: 1439 KDHDESSRIRYEITSGNIGGAFAVKNMTGAIYVAGALDYETRRR-----YELRLAAS--- 1490
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE----NLPNGFSVLQVMATDKDQGEN 338
+ LK V I + D+NDN P FE Y I E NLP VLQV ATD D+
Sbjct: 1491 DNLKENYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPK--RVLQVTATDGDKDRP 1548
Query: 339 GEFTYQL-------DDPKGA-FSIDPRSGWLTVRNQTVLDR-EAHSSLRMKVYAKETNPS 389
Y L D+P + F I+ +G + V D+ R V+A++
Sbjct: 1549 QNIVYFLTGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGE 1608
Query: 390 VVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKV--GTKTENIEYYDEQLMSFVNVEV 447
+ +AD Q K + NAP +FP V G TEN V + +
Sbjct: 1609 GLVGYADVQVNLK----DINDNAP------IFPQGVYFGNVTEN------GTAGMVVMTM 1652
Query: 448 TLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG--QNGMVLYDLQRTSNL 505
T +D +D N +Y S++ N + ++PD G + + D +RT +
Sbjct: 1653 TAVDYDDPNEGSNARLVY--SIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDY 1710
Query: 506 TI 507
+I
Sbjct: 1711 SI 1712
Score = 52.0 bits (119), Expect = 1e-04
Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 10/134 (7%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
E A D D G + + Y + +DR+ + NGS+ +++ LD + Q ++
Sbjct: 1881 EKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQNGSVTIQRSLDREVVPRHQ-----VK 1935
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD- 334
+ A +P KTA A + + + D+NDN P+F D Y + E++P V++++ATD D
Sbjct: 1936 ILAIDDGSPPKTATATLTVIVQDINDNAPKFLKD-YRPVLPEHVPPR-KVVEILATDDDD 1993
Query: 335 -QGENG-EFTYQLD 346
NG F ++LD
Sbjct: 1994 RSKSNGPPFQFRLD 2007
Score = 46.8 bits (106), Expect = 0.005
Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG--ENGEFTYQL 345
++A V I L D+ND +P F + +++E P G V QV A DKD N + Y +
Sbjct: 1281 SEATVYIMLEDVNDEIPLF-TEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIV 1339
Query: 346 DDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D P+ F I+ +SG + +TV DRE + ++V A++ PS
Sbjct: 1340 DSPRNEGKEFFEINLQSG--EIFTKTVFDREKKGAYALEVEARDGAPS 1385
Score = 46.4 bits (105), Expect = 0.006
Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 14/167 (8%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F ++ G +F+ K LD D + F V A A V++ L D+NDN
Sbjct: 1570 FDINRTTGEIFVLKPLDRDQPNGRPQWRFT--VFAQDEGGEGLVGYADVQVNLKDINDNA 1627
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKD---QGENGEFTYQ-----LDDPKGA--FS 353
P F Y ++ EN G V+ + A D D +G N Y +++ G+ F
Sbjct: 1628 PIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFE 1687
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRI 400
I+P +G + LDRE ++V A + + GT S R+
Sbjct: 1688 IEPDTGVIKTA-VCCLDRERTPDYSIQVVAMD-GGGLKGTGTASIRV 1732
Score = 44.0 bits (99), Expect = 0.032
Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 25/131 (19%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
L TN PL++ D + + +++ D + +++T+LD NDN P+F S Y+F
Sbjct: 258 LVTNRPLDREERAHYD-LSVEASDVDGLDRTVSK---IQITVLDENDNRPIF-KSLDYKF 312
Query: 468 --------SMKSNAKVG----TVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
SM+SN+ V ++GKV+A D D + Y L+ SN+ I I P
Sbjct: 313 AIAGQKSASMESNSSVTYQRFAIMGKVEATDAD---GDKIAYRLKSPSNVVI-----IVP 364
Query: 516 NTGTVSVAESP 526
TG + +A P
Sbjct: 365 QTGEIMLAGEP 375
Score = 43.6 bits (98), Expect = 0.043
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEFNQIEE 898
D+ +GV LDRE++ Y LS+ A D GL + +++ I + DENDN+P F ++
Sbjct: 251 DDESGVWLVTNRPLDREERAHYDLSVEASDVDGLDRTVSKIQITVLDENDNRPIFKSLDY 310
Query: 899 NSKVRIHRETKLNGTAGFT 917
+ + + + T
Sbjct: 311 KFAIAGQKSASMESNSSVT 329
Score = 41.1 bits (92), Expect = 0.23
Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 23/128 (17%)
Query: 1011 SEFRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNV-----------EEAQ 1058
+ + L++ A D L+ +S +++ V D ND+ P+FK Y F +
Sbjct: 270 AHYDLSVEASDVDGLDRTVSKIQITVLDENDNRPIFKSLDYKFAIAGQKSASMESNSSVT 329
Query: 1059 YTR-RVLGKVDATDADFGQNANLTYFIQ-PSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
Y R ++GKV+ATDAD + Y ++ PS+ + I P TG + + GE T ++
Sbjct: 330 YQRFAIMGKVEATDAD---GDKIAYRLKSPSNVVI---IVPQTGEIMLAGE---PTSNEL 380
Query: 1117 ILTVVARD 1124
++ V+A D
Sbjct: 381 LIEVIAHD 388
Score = 40.7 bits (91), Expect = 0.30
Identities = 32/147 (21%), Positives = 61/147 (41%), Gaps = 4/147 (2%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAE--HNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
++ F ++ +G +F + D + + + L+ A +N + + I + D
Sbjct: 1347 KEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTKFIRIGIAD 1406
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
NDN P F+ Y + EN +VL V A D D+ + + GAF++ +
Sbjct: 1407 KNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEITSGNIGGAFAVKNMT 1466
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G + V LD E +++ A +
Sbjct: 1467 GAIYVAG--ALDYETRRRYELRLAASD 1491
Score = 40.3 bits (90), Expect = 0.40
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ T +PLDRE+R Y ++V A G+ Q+T+ DENDN P+F+ Y+
Sbjct: 258 LVTNRPLDREERAHYDLSVEASDVDGLDRTVSKIQITVL--DENDNRPIFKSLDYK 311
>UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome
shotgun sequence; n=7; Euteleostomi|Rep: Chromosome 18
SCAF14485, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2244
Score = 147 bits (357), Expect = 2e-33
Identities = 164/656 (25%), Positives = 285/656 (43%), Gaps = 73/656 (11%)
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP-------NGFSVLQVMATDKDQG 336
P K+ RV +++LD NDN P F Y I + E V +V+A+D+D G
Sbjct: 9 PAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRVIASDRDDG 68
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
N E +Y ++ D G F I+P++G V ++ + L +K
Sbjct: 69 PNAEISYSIEEGDENGKFFIEPKTG--LVSSKKFSSAGEYDILTIKAVDNGRPQKSSSCR 126
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFP-----------DKVGTKTENIEYYDE------ 437
+ I K + P E++ +VF V T+ ++ + E
Sbjct: 127 LHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEASDVPVWFEITVRWG 186
Query: 438 --QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
L + V + ++D N++ P F YE ++ + GT + ++ A D D +N +
Sbjct: 187 TKALHHLLLVLIRVIDTNNHRPQF-SEKFYEVNVAEDTPPGTEVLQISASDRD-EKNKLT 244
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLA 553
L T ++ F+++P TGT+ AE+ E H L V DQ P +R
Sbjct: 245 FTLLSSTDPFSLRK-FRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDI-PVKRNLVRV 302
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLL 611
+V ++ T + P F+GAP+ V + +G++V Q+ R D +V Y L
Sbjct: 303 IVNVDDTND------NAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE 356
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVN 670
G F+++ + G ITV +L R ++ Y+ V +N + T A V + V V+
Sbjct: 357 SGNFANT-FSIDPKLGTITVAKELDRDSKAQYEL-TVKASDNGVPPLSTTAPVRIAVTVS 414
Query: 671 DERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSI-YGNGTGNVRFLIANQQDVTD 728
D + V E++ G+ + + ++ SS+ Y GN+ N D+
Sbjct: 415 DNAAP--RFTEREFSADVSESAHPGSFVALVTASSQSSVFYQIKAGNIN----NAFDINP 468
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ G + TQ+PLD E Y + + G+ + + ++++DENDN P+F
Sbjct: 469 N-----SGVVVTQRPLDYETTAQYTLVIQGTNMAGLGTNTTLL---VHLKDENDNAPIFI 520
Query: 789 HATYEGFIME----NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENT 843
+ G + E NS + T +++A+DAD NA+ +Y + F +D NT
Sbjct: 521 QKEFRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNT 580
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE--AELIIMIGDENDNKPEFNQ 895
G ++ I +LD E++ + ++ D G L +E A + I + D ND P F+Q
Sbjct: 581 GAIR-ITTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQ 635
Score = 145 bits (352), Expect = 7e-33
Identities = 156/539 (28%), Positives = 240/539 (44%), Gaps = 54/539 (10%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
TK EN + +++ V V + + D NDN PVF S+ YE + N GT + +V+A D
Sbjct: 1536 TKHENFD-----IVASVIVNIQVKDVNDNKPVF-ESDPYEAVVVENLPSGTQVIQVRASD 1589
Query: 487 PDLGQNGMVLYDLQ-RTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPA 543
D G NG V+Y L R S+ I+ F +N TG V+ + E R+ + V A+DQ
Sbjct: 1590 QDSGTNGQVIYSLDARQSSEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATDQ-- 1647
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
+R +EVT + P P F Y+ V + + V I +
Sbjct: 1648 --GDRIQHATGTRVEVTVADVNDNP--PRFTAEIYKGTVSEDDPPPSGVIAILSTTDADS 1703
Query: 604 NDVSYDLLHGYEEGVP---FAVE--ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
D++ + + G P FA+E + + V L R + Y A + +
Sbjct: 1704 EDINKQVNYFITGGDPLGQFAIEHIQNEWKVFVKKPLDREEKDNYLLNITA--SDGIFTA 1761
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVR 717
V V+D ND K +S V ENS AG I Q+ ++ + I N
Sbjct: 1762 KATVEVKVLDANDNSPQCEKALYSE---SVPENSPAGRLILQVSASD-ADIRSNAQIFYE 1817
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
A + T D ++ G + T +PLDRE+++ +R + A G A I+ V +
Sbjct: 1818 LQGAGSELFTID---SDTGELKTLQPLDREEQEEHRFKMRAVDGGGRYCEADIHVV---V 1871
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF 837
ED NDN P F Y + EN++IGT + + A D D G N+ +Y+L F
Sbjct: 1872 EDVNDNLPQFSADLYTVTVFENTEIGTYVAK---LLANDVDVGPNSNIIYSLLDSADGFF 1928
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+DE TGV+ + LDRE + Y+L +A D G LSS ++++ + D NDN P F
Sbjct: 1929 SIDEQTGVIS-LERPLDRELQSTYELRALASDQGLPRLSSVCQVVVSVLDINDNPPVFEH 1987
Query: 896 IEENSKV-----------RIH---RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLI 940
E + V R+ R+T+ NG + II F++D + G +F+I
Sbjct: 1988 REYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGIISGNEHGLFSVD-PRTGDIFVI 2045
Score = 140 bits (339), Expect = 3e-31
Identities = 133/467 (28%), Positives = 217/467 (46%), Gaps = 33/467 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ F V V L D NDN P F ++ Y+ ++ S+ GT + ++ A D D G N + Y +
Sbjct: 1331 VGFCVVNVILTDINDNAPQFRAAD-YKSTIASDVPRGTSVVRISASDLDEGSNADIEYSI 1389
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI-LEGR-HALFVEASDQPANPSERRYSLAVVTI 557
+ + F+I+P +G + ES I LE +A FV A D NP + +S+ V I
Sbjct: 1390 EADVE-NVEENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDT-GNPPQ--HSVVQVNI 1445
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY--E 615
+ + IP F A Y + V ++ IGT + I+ A + Y L+ G E
Sbjct: 1446 RIV----APETPIPKFNEAQYRYTVAEDLPIGTEIDVIQAESA---QPLIYSLVKGSTPE 1498
Query: 616 EGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVND 671
F V+ SG + + L Y F + ++ N IV + V+ V DVND
Sbjct: 1499 SNADEVFVVDRDSGALKLQKSLDHETTKWYQFLLHSQTKHENFDIVASVIVNIQVKDVND 1558
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ--QDVTDD 729
+ V + ++ V+ +G + Q+ ++ S G + L A Q +++++
Sbjct: 1559 NKPVFESDPYEAVV--VENLPSGTQVIQVRASDQDS--GTNGQVIYSLDARQSSEEISEL 1614
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
A+ +E G + T K LDREK Y + V+A I A +V + + D NDNPP F
Sbjct: 1615 FAVNSETGWVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFT 1674
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLF-GEGKEMFDVDENTGVV 846
Y+G + E+ + + I+ TDAD E N Y + G+ F ++
Sbjct: 1675 AEIYKGTVSEDDPPPSGVIA--ILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEW 1732
Query: 847 K-FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
K F+ LDRE+K Y L++ A D G +++A + + + D NDN P+
Sbjct: 1733 KVFVKKPLDREEKDNYLLNITASD-GIFTAKATVEVKVLDANDNSPQ 1778
Score = 116 bits (280), Expect = 4e-24
Identities = 131/475 (27%), Positives = 215/475 (45%), Gaps = 50/475 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V++ L D NDN PVF+ S Y ++ + VGT I +V A D D G N V + L
Sbjct: 1019 SDVFVDIILEDVNDNAPVFL-SKAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLV 1077
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQ--PANPSERRYSLAVVT 556
+ + F I+ +TGT+S A+ E +H L V A D+ PA SE +VT
Sbjct: 1078 EEKGES-SDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPALSSE-----VIVT 1131
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGY 614
I+VT + P+F Y + G + Q++ +DA +++++ + G
Sbjct: 1132 IDVT----DLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLFFFTSGN 1187
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDF-----EAVALQENANLSIVTNATVHVVDV 669
E+ + F++++ +G I + + + +P Y+ + V A L V A H
Sbjct: 1188 ED-LNFSIDKHTGAILISNHRRVHMQPFYNLSVSVSDGVFRSSAAVLVTVIGANFHSPTF 1246
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
+ V+ HS I V E A A I+ G +R+ I N D
Sbjct: 1247 SQTEFVVELVEHSEIYTPVAEAKATDADEGIY------------GQIRYQIVN-DFAKDK 1293
Query: 730 IAIAEDGTIFTQKPLDREK--RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
++ E+G IFT + LDRE V ++++A G + G V + + D NDN P F
Sbjct: 1294 FSVNENGEIFTLESLDRENNMEKVVPISLVARDGGGKV---GFCVVNVILTDINDNAPQF 1350
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GKEMFDVDENTG 844
A Y+ I + GT + I A+D DEG+NA Y++ + +E F++ +G
Sbjct: 1351 RAADYKSTIASDVPRGTSVVR---ISASDLDEGSNADIEYSIEADVENVEENFEIHPTSG 1407
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
++ +SL + +Y + A+DTG S ++ I I P+FN+ +
Sbjct: 1408 LI-VTKESLIGLENELYAFFVRAKDTGNPPQHSVVQVNIRIVAPETPIPKFNEAQ 1461
Score = 116 bits (279), Expect = 5e-24
Identities = 133/462 (28%), Positives = 207/462 (44%), Gaps = 37/462 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V + V + DANDN P+FV NL Y ++ +A+ G +I +V AVD D+GQN + Y L+
Sbjct: 819 VLLTVMVEDANDNRPMFV--NLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKE 876
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEV 559
F+I+P +G +S+ + E + F V + NP+ A V + V
Sbjct: 877 HQEF-----FQISP-SGEISLKKKLQKESLNTDFVIVVVAQDNGNPA----LSAEVEVPV 926
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T K +P F A Y + N+ + T V ++ N++ E + Y + G +
Sbjct: 927 TVVNKA----MPAFEKAFYTIEIPENIQLHTPVLHVQANNS-EGPRIVYTISEG-DPFKQ 980
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F+++ +GVI V+ L P Y A + + DVND V L
Sbjct: 981 FSIDFNTGVIHVIQPLDFETHPAYKLSVRATDSLTGAHSDVFVDIILEDVNDNAPVFLSK 1040
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTN-MSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GT 737
A +H + A +I + S GN L+ + + +D I D GT
Sbjct: 1041 A-----YHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTGT 1095
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T + LD E+ + + V A ++GV + + VTI + D NDN P F TY I
Sbjct: 1096 ISTAQLLDYEEIRQHELRVRA-VDRGVPALSSEVIVTIDVTDLNDNAPEFTQQTYNSTIS 1154
Query: 798 ENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
E + G I ++A+DAD + N LF +T E F +D++TG + I +
Sbjct: 1155 ELAPRGHFITQ---VQASDADSSDKDNLLFFFTSGNEDLN-FSIDKHTGAI-LISNHRRV 1209
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ Y LS+ D SS A L+ +IG N + P F+Q E
Sbjct: 1210 HMQPFYNLSVSVSDGVFRSSAAVLVTVIG-ANFHSPTFSQTE 1250
Score = 116 bits (279), Expect = 5e-24
Identities = 141/522 (27%), Positives = 224/522 (42%), Gaps = 54/522 (10%)
Query: 349 KGAFSID--PRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWR-- 404
KG S D P SG + + + T D E + +V T +G FA +W+
Sbjct: 1679 KGTVSEDDPPPSGVIAILSTTDADSE---DINKQVNYFITGGDPLGQFAIEHIQNEWKVF 1735
Query: 405 -RQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSN 463
++PL+ EK Y+ NI D + VEV +LDANDN+P +
Sbjct: 1736 VKKPLDRE---EKDNYLL---------NITASDGIFTAKATVEVKVLDANDNSPQCEKA- 1782
Query: 464 LYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA 523
LY S+ N+ G +I +V A D D+ N + Y+LQ + F I+ +TG +
Sbjct: 1783 LYSESVPENSPAGRLILQVSASDADIRSNAQIFYELQGAG----SELFTIDSDTGELKTL 1838
Query: 524 ESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW 581
+ E + H + A D RY A + + V + ++P F Y
Sbjct: 1839 QPLDREEQEEHRFKMRAVD-----GGGRYCEADIHVVV----EDVNDNLPQFSADLYTVT 1889
Query: 582 VGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN 639
V N IGT V ++ N D +++ Y LL +G F+++E++GVI++ L R
Sbjct: 1890 VFENTEIGTYVAKLLANDVDVGPNSNIIYSLLDS-ADGF-FSIDEQTGVISLERPLDREL 1947
Query: 640 RPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAI 697
+ Y+ A+A + LS V V V+D+ND V H V E+ S G
Sbjct: 1948 QSTYELRALASDQGLPRLSSVCQVVVSVLDINDNPPVF---EHREYTATVSEDVSVGT-- 2002
Query: 698 GQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVI 757
Q+ +S G + + I + + G IF +PLD E Y +TV
Sbjct: 2003 -QLLRVQAASRDTEANGEISYGIISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVE 2061
Query: 758 AEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
A + G + + V I + D NDN PVF Y + E++++G K + A D
Sbjct: 2062 AT-DGGSPPLSDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAELG---KTVITVNAEDL 2117
Query: 818 DEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKK 858
D +++ Y++ G F +D G +K + LDRE++
Sbjct: 2118 DGPSHSHVRYSIVDGNQGSPFTIDSARGELK-VAHQLDRERE 2158
Score = 102 bits (245), Expect = 7e-20
Identities = 117/461 (25%), Positives = 194/461 (42%), Gaps = 29/461 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ V V V + D NDN P FV + + + +A VG+ + +V A D D G+N V+Y L+
Sbjct: 298 NLVRVIVNVDDTNDNAPWFVGAP-FSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE 356
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
+ N T F I+P GT++VA+ + + + L V+ASD P + A V I
Sbjct: 357 -SGNFANT--FSIDPKLGTITVAKELDRDSKAQYELTVKASDNGVPPLS---TTAPVRIA 410
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
VT P F + V + G+ V + A Q+ V Y + G
Sbjct: 411 VTVSDNA----APRFTEREFSADVSESAHPGSFVALVT---ASSQSSVFYQIKAGNINNA 463
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F + SGV+ L Y + A L T VH+ D ND + ++
Sbjct: 464 -FDINPNSGVVVTQRPLDYETTAQYTL-VIQGTNMAGLGTNTTLLVHLKDENDNAPIFIQ 521
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD-IAI-AEDG 736
++ ++ + + + +G N + + + AI + G
Sbjct: 522 KEFRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTG 581
Query: 737 TIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
I LD E+R+ + TV + + + VTI + D ND PPVF TYE
Sbjct: 582 AIRITTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEAT 641
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLD 854
++ + G ++ I ATD+D G NA + ++ G + F +D TG++ +
Sbjct: 642 VITPTYKGVKVIQ---INATDSDSGPNAKLLLSISEGNIGDKFKMDPTTGIISVQNVTQL 698
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
R + Y+L + D G SS A + I + + +NK +F +
Sbjct: 699 RSR---YELKVRVSD-GRFSSVATVKINVKENKENKLKFTK 735
Score = 99.1 bits (236), Expect = 8e-19
Identities = 105/421 (24%), Positives = 187/421 (44%), Gaps = 44/421 (10%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGV 628
P A Y V N G + Q+ +DA +++ + Y+L E F ++ +G
Sbjct: 1777 PQCEKALYSESVPENSPAGRLILQVSASDADIRSNAQIFYELQGAGSE--LFTIDSDTGE 1834
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIF 686
+ + L R + + F+ A+ A +HVV DVND ++ +F
Sbjct: 1835 LKTLQPLDREEQEEHRFKMRAVDGGGRYC---EADIHVVVEDVNDNLPQFSADLYTVTVF 1891
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
E G + ++ ++ N+ + + + D I + G I ++PLDR
Sbjct: 1892 ENTE--IGTYVAKLLANDVDV---GPNSNIIYSLLDSADGFFSID-EQTGVISLERPLDR 1945
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E + Y + +A ++G+ + + QV + + D NDNPPVFEH Y + E+ +GT++
Sbjct: 1946 ELQSTYELRALAS-DQGLPRLSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQL 2004
Query: 807 KMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
++A D N Y + G +F VD TG + F+ LD E Y +++
Sbjct: 2005 LR---VQAASRDTEANGEISYGIISGNEHGLFSVDPRTGDI-FVIQPLDYEASHEYYITV 2060
Query: 866 VARDTGG--LSSEAELIIMIGDENDNKPEFNQ------IEENSK-----VRIHRETKLNG 912
A D G LS A + I + D NDN+P F+Q + E+++ + ++ E L+G
Sbjct: 2061 EATDGGSPPLSDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAELGKTVITVNAE-DLDG 2119
Query: 913 TA----GFTIIEVKPKNKFALD-----VDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
+ ++I++ + F +D + L EN P GT++++L D D+ N
Sbjct: 2120 PSHSHVRYSIVDGNQGSPFTIDSARGELKVAHQLDRERENRPKGTSVLQLTVTDRDASHN 2179
Query: 964 G 964
G
Sbjct: 2180 G 2180
Score = 97.1 bits (231), Expect = 3e-18
Identities = 225/998 (22%), Positives = 385/998 (38%), Gaps = 145/998 (14%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + S V++ + + +N F + Y+ ++ N+ + + AV + N +
Sbjct: 710 DGRFSSVATVKINVKENKENKLKFTKES-YKAFVQENSSEKKTLEVIAAVGNQV--NEPL 766
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y++ L F+I+ +G VS P F E + + V+
Sbjct: 767 FYNI-----LNPDKKFEISRTSGVVSTTGIPFDREAQDTF-EIVVEVTREGQSEDGAHVL 820
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGY 614
+ N+P F+ PY V + G + Q+ D QN LL +
Sbjct: 821 LTVMVEDANDNRPM---FVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEH 877
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+E F SG I++ L + + V Q+N N ++ V V VN
Sbjct: 878 QE---FFQISPSGEISLKKKLQKESLNTDFVIVVVAQDNGNPALSAEVEVPVTVVNKAMP 934
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA-NQQDVTDDIAIA 733
K ++ + EN HT + + N + R + ++ D +I
Sbjct: 935 AFEKAFYT---IEIPENIQ-------LHTPVLHVQANNSEGPRIVYTISEGDPFKQFSID 984
Query: 734 -EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA-GIYQVTIYIEDENDNPPVFEHAT 791
G I +PLD E Y+++V A + ++GA V I +ED NDN PVF
Sbjct: 985 FNTGVIHVIQPLDFETHPAYKLSVRATDS---LTGAHSDVFVDIILEDVNDNAPVFLSKA 1041
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + E S +GT I + A D+D G N + L V+E G+
Sbjct: 1042 YHANVSEASVVGTRILQ---VDAKDSDTGNNQEVFFQL---------VEEK-------GE 1082
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENS-KVR-IHRETK 909
S D + RDTG +S+ A+L+ ++ +I ++ +VR + R
Sbjct: 1083 SSD--------FFTIDRDTGTIST-AQLL-----------DYEEIRQHELRVRAVDRGVP 1122
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
+ I+V N A + Q I E P G I ++ A D DS + +
Sbjct: 1123 ALSSEVIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLFF 1182
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA--RSLPPESEFRLNISALDGGNLND 1027
F S + L F I++ G ++++ R + + + L++S DG
Sbjct: 1183 FTS---------GNEDLN----FSIDKHTGAILISNHRRVHMQPFYNLSVSVSDGV-FRS 1228
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+ +V V V N H P F +T + + E + + ATDAD G + Y I
Sbjct: 1229 SAAVLVTVIGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVND 1288
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETE-DKYI-LTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
F ++ G + LDRE +K + +++VARD G D+N
Sbjct: 1289 FAKDKFSVNE-NGEIFTLESLDRENNMEKVVPISLVARDGGGKVGFCVVNVILT---DIN 1344
Query: 1146 DNSPKFYAFD-------------ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI 1192
DN+P+F A D ++ + DE SN + E + V +EEN I
Sbjct: 1345 DNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNADIEYSIEADV--ENVEENFEI 1402
Query: 1193 GTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMS 1252
T + ++ IG N L + + ++ G P S ++ V + V E +
Sbjct: 1403 HPTSGLIVTKES-LIGLENELYAFFV----RAKDTGNPPQHS--VVQVNIRIVAPETPI- 1454
Query: 1253 DKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDT---DIRRTFVID 1309
P F Y + E++ E+ + E+ + Y L + T + FV+D
Sbjct: 1455 --PKFNEAQYRYTVAEDLPIGTEIDVIQA----ESAQPLIYSLVKGSTPESNADEVFVVD 1508
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVR 1369
+G L L +S D E Y+ ++ ++ + H + + V+ V ++
Sbjct: 1509 RDSGALKLQKSLDHETTKWYQFLLHSQTK-------HENFDIVASVI---------VNIQ 1552
Query: 1370 IKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGA 1407
+KDVNDN P F + P + P G QV+Q++ +
Sbjct: 1553 VKDVNDNKPVFESD--PYEAVVVENLPSGTQVIQVRAS 1588
Score = 95.1 bits (226), Expect = 1e-17
Identities = 104/401 (25%), Positives = 163/401 (40%), Gaps = 48/401 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P G I++++A D D N QI YE S+L F I+ G
Sbjct: 1788 VPENSPAGRLILQVSASDADIRSNAQIFYELQGA----GSEL----------FTIDSDTG 1833
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E E R + A+DGG + V V+DVND+ P F Y V E
Sbjct: 1834 ELKTLQPLDREEQEEHRFKMRAVDGGGRYCEADIHVVVEDVNDNLPQFSADLYTVTVFEN 1893
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ K+ A D D G N+N+ Y + S D F I TGV+S+ LDRE + Y
Sbjct: 1894 TEIGTYVAKLLANDVDVGPNSNIIYSLLDS-ADGFFSIDEQTGVISLERPLDRELQSTYE 1952
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L +A D G D+NDN P F E E+ ++++S
Sbjct: 1953 LRALASDQG-LPRLSSVCQVVVSVLDINDNPPVF----EHREYTATVSEDVS----VGTQ 2003
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIG----NGNGLILYSLPQRKNQQ-------- 1225
++ V A+ + A + + N+ G+ ++ L + +
Sbjct: 2004 LLRVQAASRDTEANGEISYGIISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVEAT 2063
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL--TE 1283
+ G P LS A + + + DV D ++PVF Y + E+ ++++N +
Sbjct: 2064 DGGSPPLSDMATVNINLTDVND-----NRPVFSQDVYTAVVSEDAELGKTVITVNAEDLD 2118
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
+ +RY I++ N F ID G L + DRE
Sbjct: 2119 GPSHSHVRYSIVDGNQGS---PFTIDSARGELKVAHQLDRE 2156
Score = 94.7 bits (225), Expect = 2e-17
Identities = 118/455 (25%), Positives = 199/455 (43%), Gaps = 40/455 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
NV + + D ND PVF YE ++ + G + ++ A D D G N +L + S
Sbjct: 618 NVTIEVTDVNDCPPVF-SQKTYEATVITPTYKGVKVIQINATDSDSGPNAKLLLSI---S 673
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
I FK++P TG +SV L R+ L V SD R+S +V T+++
Sbjct: 674 EGNIGDKFKMDPTTGIISVQNVTQLRSRYELKVRVSD-------GRFS-SVATVKI--NV 723
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE 623
K NK + F Y+ +V N ++ I + Y++L+ ++ F +
Sbjct: 724 KENKENKLKFTKESYKAFVQENSSEKKTLEVIAAVGNQVNEPLFYNILNPDKK---FEIS 780
Query: 624 ERSGVITVVD-DLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGAH 681
SGV++ R + ++ +E + TV V D ND R + + +
Sbjct: 781 RTSGVVSTTGIPFDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPY 840
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
++ + G I Q+ T + G +++L+ Q+ I+ G I +
Sbjct: 841 HALV--QMDAEEGHLIRQV--TAVDRDMGQ-NAEIQYLLKEHQEF---FQISPSGEISLK 892
Query: 742 KPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
K L +E + + + V+A+ N A +V + + N P FE A Y I EN
Sbjct: 893 KKLQKESLNTDFVIVVVAQDNGNPALSA---EVEVPVTVVNKAMPAFEKAFYTIEIPENI 949
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKI 859
++ T + ++A ++ EG +YT+ G+ + F +D NTGV+ I LD E
Sbjct: 950 QLHTPVLH---VQANNS-EGPR--IVYTISEGDPFKQFSIDFNTGVIHVI-QPLDFETHP 1002
Query: 860 MYKLSLVARDT-GGLSSEAELIIMIGDENDNKPEF 893
YKLS+ A D+ G S+ + I++ D NDN P F
Sbjct: 1003 AYKLSVRATDSLTGAHSDVFVDIILEDVNDNAPVF 1037
Score = 93.1 bits (221), Expect = 5e-17
Identities = 104/368 (28%), Positives = 158/368 (42%), Gaps = 72/368 (19%)
Query: 1001 VIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
V V + L E + + LNI+A DG +V V V D ND+ P +K Y+ +V E
Sbjct: 1734 VFVKKPLDREEKDNYLLNITASDG-IFTAKATVEVKVLDANDNSPQCEKALYSESVPENS 1792
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
R++ +V A+DAD NA + Y +Q + ++L F I TG L LDRE ++++
Sbjct: 1793 PAGRLILQVSASDADIRSNAQIFYELQGAGSEL-FTIDSDTGELKTLQPLDREEQEEHRF 1851
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
+ A D G DVNDN P+F A
Sbjct: 1852 KMRAVDGGGRYCEADIHVVVE---DVNDNLPQFSA------------------------- 1883
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGN-------------------GLILYSLP 1219
+Y T+ EN IGT VAK+ AND D N N G+I P
Sbjct: 1884 -DLYTVTVFENTEIGTYVAKLLANDVDVGPNSNIIYSLLDSADGFFSIDEQTGVISLERP 1942
Query: 1220 QRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
+ Q+ GLP LSS ++V+V D+ D + PVF R Y + E+
Sbjct: 1943 LDRELQSTYELRALASDQGLPRLSSVCQVVVSVLDIND-----NPPVFEHREYTATVSED 1997
Query: 1270 VNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
V+ +L+ + N ++ Y I++ N+ + F +DPR G +++++ D E
Sbjct: 1998 VSVGTQLLRVQAASRDTEANGEISYGIISGNEHGL---FSVDPRTGDIFVIQPLDYEASH 2054
Query: 1328 TYEVIVRA 1335
Y + V A
Sbjct: 2055 EYYITVEA 2062
Score = 92.7 bits (220), Expect = 7e-17
Identities = 155/609 (25%), Positives = 246/609 (40%), Gaps = 86/609 (14%)
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDN 889
F E + + V E+ + I D + E SLV T +++ E+ ++ D
Sbjct: 1457 FNEAQYRYTVAEDLPIGTEI-DVIQAESAQPLIYSLVKGSTPESNAD-EVFVVDRDSGAL 1514
Query: 890 KPEFNQIEENSK---VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF-------L 939
K + + E +K +H +TK F I+ N DV+ P+F +
Sbjct: 1515 KLQKSLDHETTKWYQFLLHSQTKHEN---FDIVASVIVNIQVKDVNDNKPVFESDPYEAV 1571
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+P GT +I++ A D DSG NGQ+ Y + ++ S++ E+ F +N G
Sbjct: 1572 VVENLPSGTQVIQVRASDQDSGTNGQVIYSLD-------ARQSSE--EISELFAVNSETG 1622
Query: 1000 HVIVARSLPPESEFRLNISAL--DGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNV 1054
V + L E R I+ L D G+ + + V V V DVND+ P F Y V
Sbjct: 1623 WVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGTV 1682
Query: 1055 -EEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDR 1110
E+ V+ + TDAD N + YFI D F I + + V LDR
Sbjct: 1683 SEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEWKVFVKKPLDR 1742
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E +D Y+L + A D D NDNSP+ L PE
Sbjct: 1743 EEKDNYLLNITASDG----IFTAKATVEVKVLDANDNSPQ--CEKALYSESVPENSPAG- 1795
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTV----AKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
++ + A I NA I + +++F D+D G L L + + +++
Sbjct: 1796 ---RLILQVSASDADIRSNAQIFYELQGAGSELFTIDSD---TGELKTLQPLDREEQEEH 1849
Query: 1227 -LGLPSLSS-----TAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL- 1279
+ ++ A + V V DV D + P F + Y + + EN + L
Sbjct: 1850 RFKMRAVDGGGRYCEADIHVVVEDVNDNL-----PQFSADLYTVTVFENTEIGTYVAKLL 1904
Query: 1280 -NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
N + N + Y +L+ D F ID + G + L R DRE++ TYE+ A Q
Sbjct: 1905 ANDVDVGPNSNIIYSLLDSAD----GFFSIDEQTGVISLERPLDRELQSTYELRALASDQ 1960
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
LP + V + VVV + D+NDN P F +R + G
Sbjct: 1961 ----GLPRL-----SSVCQ--------VVVSVLDINDNPPVFE--HREYTATVSEDVSVG 2001
Query: 1399 YQVMQLKGA 1407
Q+++++ A
Sbjct: 2002 TQLLRVQAA 2010
Score = 89.8 bits (213), Expect = 5e-16
Identities = 86/303 (28%), Positives = 136/303 (44%), Gaps = 26/303 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPRG--- 137
+ V +EDVNDN+P F Y VTV E T G L +GP+ I ++
Sbjct: 1867 IHVVVEDVNDNLPQFSADLYTVTVFENTEIGTYVAKLLANDVDVGPNSNIIYSLLDSADG 1926
Query: 138 -LTIFKDIRAFDRDKPNTPNSDVHYSIVS-GNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
+I + ++P Y + + +D G L S + V+ VLD +
Sbjct: 1927 FFSIDEQTGVISLERPLDRELQSTYELRALASDQGLPRLSSVCQVVV---SVLDINDNPP 1983
Query: 196 EFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
F+ ++ + ++L + A +D + Y +ISGN+ LFS+D G
Sbjct: 1984 VFEHREYTATVSEDVSVGTQLL---RVQAASRDTEANGEISYGIISGNEHGLFSVDPRTG 2040
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+F+ + LD +A H + + V+A+ +P + A V I L D+NDN P F D Y
Sbjct: 2041 DIFVIQPLDYEASHE-----YYITVEATDGGSPPLSDMATVNINLTDVNDNRPVFSQDVY 2095
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA-FSIDPRSGWLTVRNQTVL 369
+ E+ G +V+ V A D D + Y + D +G+ F+ID G L V +Q L
Sbjct: 2096 TAVVSEDAELGKTVITVNAEDLDGPSHSHVRYSIVDGNQGSPFTIDSARGELKVAHQ--L 2153
Query: 370 DRE 372
DRE
Sbjct: 2154 DRE 2156
Score = 89.0 bits (211), Expect = 9e-16
Identities = 91/358 (25%), Positives = 159/358 (44%), Gaps = 40/358 (11%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V + D NDN P F ++LY ++ N ++GT + K+ A D D+G N ++Y L ++
Sbjct: 1866 DIHVVVEDVNDNLPQF-SADLYTVTVFENTEIGTYVAKLLANDVDVGPNSNIIYSLLDSA 1924
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F I+ TG +S+ E P+ L+ + L ASDQ R S+ V + V
Sbjct: 1925 D----GFFSIDEQTGVISL-ERPLDRELQSTYELRALASDQGL---PRLSSVCQVVVSVL 1976
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGV 618
+ P P F Y V +V +GT + +++ D ++SY ++ G E G+
Sbjct: 1977 --DINDNP--PVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGIISGNEHGL 2032
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
F+V+ R+G I V+ L Y A + LS + +++ DVND R V
Sbjct: 2033 -FSVDPRTGDIFVIQPLDYEASHEYYITVEATDGGSPPLSDMATVNINLTDVNDNRPVFS 2091
Query: 678 KGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ ++ ++ S A +G+ + N + G +VR+ I + + + G
Sbjct: 2092 QDVYTAVV------SEDAELGKTVITVNAEDLDGPSHSHVRYSIVDGNQGSPFTIDSARG 2145
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+ LDRE+ N+ G + Q+T+ D + N P F A +G
Sbjct: 2146 ELKVAHQLDRERE-----------NRP--KGTSVLQLTVTDRDASHNGPPFTFAIVDG 2190
Score = 87.0 bits (206), Expect = 3e-15
Identities = 97/407 (23%), Positives = 176/407 (43%), Gaps = 33/407 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+ G+ +S+ + VT+ + D+NDN P F Y+ T+ EL P G FI + +
Sbjct: 1117 VDRGVPALSSEVIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGH--FITQVQASDADSS 1174
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPN-----TPNSDVH----YSIVSGNDDGHFALESSHKP 180
+ T + F DK + + VH Y++ DG F ++
Sbjct: 1175 DKDNLLFFFTSGNEDLNFSIDKHTGAILISNHRRVHMQPFYNLSVSVSDGVFRSSAAVLV 1234
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGVGATLRYELISGN 239
++ EF + ++ H EI P A D D G+ +RY++++
Sbjct: 1235 TVIGANFHSPTFSQTEFVVELVE-----HSEIYTPVAEAKATDADEGIYGQIRYQIVNDF 1289
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+ FS++ NG +F + LD E+N++ V+ + + K V + L D+
Sbjct: 1290 AKDKFSVNE-NGEIFTLESLD--RENNMEK---VVPISLVARDGGGKVGFCVVNVILTDI 1343
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSID 355
NDN P+F Y +I ++P G SV+++ A+D D+G N + Y + ++ + F I
Sbjct: 1344 NDNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNADIEYSIEADVENVEENFEIH 1403
Query: 356 PRSGWLTVRNQTV-LDREAHSSLRMKVYAKET-NPSVVGTFADSQRIAKWRRQPLETNAP 413
P SG + + + L+ E ++ V AK+T NP + RI + N
Sbjct: 1404 PTSGLIVTKESLIGLENELYAFF---VRAKDTGNPPQHSVVQVNIRIVAPETPIPKFNEA 1460
Query: 414 LEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV 460
+ T +GT+ + I+ Q + + V+ + ++N + VFV
Sbjct: 1461 QYRYTVAEDLPIGTEIDVIQAESAQPLIYSLVKGSTPESNADE-VFV 1506
Score = 85.4 bits (202), Expect = 1e-14
Identities = 58/166 (34%), Positives = 87/166 (52%), Gaps = 17/166 (10%)
Query: 231 LRYELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
L Y L+ G N ++F +D +G+L L+K LD + Q F+L Q N +
Sbjct: 1487 LIYSLVKGSTPESNADEVFVVDRDSGALKLQKSLDHETTKWYQ---FLLHSQTKHENFDI 1543
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
A V I++ D+NDN P FE D Y +VENLP+G V+QV A+D+D G NG+ Y L
Sbjct: 1544 -VASVIVNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSL 1602
Query: 346 DDPKGA------FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D + + F+++ +GW+T + LDRE + V A +
Sbjct: 1603 DARQSSEEISELFAVNSETGWVTTLKE--LDREKMQRYTIAVLATD 1646
Score = 82.6 bits (195), Expect = 8e-14
Identities = 76/288 (26%), Positives = 126/288 (43%), Gaps = 26/288 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + + Y L+ D FS+D G + LE+ LD + + +T+ L+ AS
Sbjct: 1905 ANDVDVGPNSNIIYSLLDSADG-FFSIDEQTGVISLERPLDRELQ-----STYELRALAS 1958
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ +V + +LD+NDN P FE Y ++ E++ G +L+V A +D NG
Sbjct: 1959 DQGLPRLSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANG 2018
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS 397
E +Y + + G FS+DPR+G + V LD EA + V A + + A
Sbjct: 2019 EISYGIISGNEHGLFSVDPRTGDIFVIQP--LDYEASHEYYITVEATDGGSPPLSDMA-- 2074
Query: 398 QRIAKWRRQPLETNAPLEK----TTYVFPD-KVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
+ N P+ T V D ++G + D S +V +++D
Sbjct: 2075 --TVNINLTDVNDNRPVFSQDVYTAVVSEDAELGKTVITVNAEDLDGPSHSHVRYSIVDG 2132
Query: 453 NDNNPVFVPSNLYEFSM-------KSNAKVGTVIGKVKAVDPDLGQNG 493
N +P + S E + + N GT + ++ D D NG
Sbjct: 2133 NQGSPFTIDSARGELKVAHQLDRERENRPKGTSVLQLTVTDRDASHNG 2180
Score = 81.4 bits (192), Expect = 2e-13
Identities = 83/323 (25%), Positives = 144/323 (44%), Gaps = 29/323 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE--KAFIFLIAPIGPSLTI 130
G ++ A++ +TV +ED NDN P+F++ PYH V G + + +G + I
Sbjct: 811 GQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEI 870
Query: 131 PLTVPRGLTIFK-----DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS-HKPVLLL 184
+ F+ +I + + + N+D +V D+G+ AL + PV ++
Sbjct: 871 QYLLKEHQEFFQISPSGEISLKKKLQKESLNTD-FVIVVVAQDNGNPALSAEVEVPVTVV 929
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
K + A +K F + + ++H P+ + + G + Y + G+ K F
Sbjct: 930 NKAM--PAFEKAFYTIEIPENIQLH------TPVLHVQANNSEGPRIVYTISEGDPFKQF 981
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+D G + + + LD + + L V+A+ + V+I L D+NDN P
Sbjct: 982 SIDFNTGVIHVIQPLDFETH-----PAYKLSVRATDSLTGAH-SDVFVDIILEDVNDNAP 1035
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPRSGW 360
F Y+ ++ E G +LQV A D D G N E +QL + KG F+ID +G
Sbjct: 1036 VFLSKAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTG- 1094
Query: 361 LTVRNQTVLDREAHSSLRMKVYA 383
T+ +LD E ++V A
Sbjct: 1095 -TISTAQLLDYEEIRQHELRVRA 1116
Score = 80.2 bits (189), Expect = 4e-13
Identities = 51/169 (30%), Positives = 89/169 (52%), Gaps = 11/169 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+ A + YEL G +LF++DS G L + LD + + + + F ++
Sbjct: 1801 VSASDADIRSNAQIFYEL-QGAGSELFTIDSDTGELKTLQPLDREEQ---EEHRFKMRA- 1855
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++ + +A + + + D+NDNLP+F D Y +++ EN G V +++A D D G
Sbjct: 1856 ---VDGGGRYCEADIHVVVEDVNDNLPQFSADLYTVTVFENTEIGTYVAKLLANDVDVGP 1912
Query: 338 NGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y LD G FSID ++G +++ + LDRE S+ ++ A +
Sbjct: 1913 NSNIIYSLLDSADGFFSIDEQTGVISL--ERPLDRELQSTYELRALASD 1959
Score = 77.4 bits (182), Expect = 3e-12
Identities = 103/430 (23%), Positives = 171/430 (39%), Gaps = 45/430 (10%)
Query: 988 VKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
+ F IN G V+ R L E+ ++ L I + L N ++ V +KD ND+ P+F
Sbjct: 460 INNAFDINPNSGVVVTQRPLDYETTAQYTLVIQGTNMAGLGTNTTLLVHLKDENDNAPIF 519
Query: 1046 -KKTWYNFNVEEAQYTRRVLGK------VDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
+K + E A VL + V A+DAD QNA L Y I F I
Sbjct: 520 IQKEFRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSN 579
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
TG + + LD E + + TV D G DVND P F
Sbjct: 580 TGAIRITTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVF------ 633
Query: 1158 LEWKHPEADELS-NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-L 1215
K EA ++ + V+ I + NA + ++++ D + G+I +
Sbjct: 634 -SQKTYEATVITPTYKGVKVIQINATDSDSGPNAKLLLSISEGNIGDKFKMDPTTGIISV 692
Query: 1216 YSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
++ Q +++ L + +S V + + +K F Y+ ++EN +
Sbjct: 693 QNVTQLRSRYELKV-RVSDGRFSSVATVKINVKENKENKLKFTKESYKAFVQENSSEKKT 751
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVR 1334
L + + N + Y ILN + + F I +G + P DRE +DT+E++V
Sbjct: 752 LEVIAAVGNQVNEPLFYNILNPD-----KKFEISRTSGVVSTTGIPFDREAQDTFEIVVE 806
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTT 1394
R+ S + H++ + V ++D NDN P F N P +
Sbjct: 807 VTREGQSEDGAHVL-----------------LTVMVEDANDNRPMFV--NLPYHALVQMD 847
Query: 1395 APFGYQVMQL 1404
A G+ + Q+
Sbjct: 848 AEEGHLIRQV 857
Score = 77.0 bits (181), Expect = 4e-12
Identities = 55/170 (32%), Positives = 84/170 (49%), Gaps = 12/170 (7%)
Query: 231 LRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
L + L+S D + F LD G+L+ + LD + H+ +L V + P+K
Sbjct: 243 LTFTLLSSTDPFSLRKFRLDPGTGTLYTAETLDHETMHH-----HILTVMVRDQDIPVKR 297
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
RV + + D NDN P F ++ + E+ G +VLQV A DKD+G N E Y L+
Sbjct: 298 NLVRVIVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLES 357
Query: 348 PKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
A FSIDP+ G +TV + LDR++ + + V A + + T A
Sbjct: 358 GNFANTFSIDPKLGTITVAKE--LDRDSKAQYELTVKASDNGVPPLSTTA 405
Score = 75.4 bits (177), Expect = 1e-11
Identities = 105/455 (23%), Positives = 181/455 (39%), Gaps = 52/455 (11%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ I T + + A D D G+ GQIRY+ ++ K F +NE +G +
Sbjct: 1257 EHSEIYTPVAEAKATDADEGIYGQIRYQIVNDF-------------AKDKFSVNE-NGEI 1302
Query: 1002 IVARSLPPESEFR----LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
SL E+ +++ A DGG V V + D+ND+ P F+ Y +
Sbjct: 1303 FTLESLDRENNMEKVVPISLVARDGGGKVGFCVVNVILTDINDNAPQFRAADYKSTIASD 1362
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ ++ A+D D G NA++ Y I+ + + FEI P +G++ L +
Sbjct: 1363 VPRGTSVVRISASDLDEGSNADIEYSIEADVENVEENFEIHPTSGLIVTKESLIGLENEL 1422
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPEADELSNHNF 1173
Y V A+D G PKF + + P E+
Sbjct: 1423 YAFFVRAKDTGNPPQHSVVQVNIRIVAP-ETPIPKFNEAQYRYTVAEDLPIGTEIDVIQA 1481
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLS 1233
ES P+ + ++ + P + +VF D D +G + SL + L
Sbjct: 1482 ESAQ--PLIYSLVKGSTP-ESNADEVFVVDRD---SGALKLQKSLDHETTKWYQFLLHSQ 1535
Query: 1234 STAILMVTVADVPDEVEMSD----KPVFISRYYELEIEENVNAPVELVSLNLTEHYE--N 1287
+ VA V +++ D KPVF S YE + EN+ + +++ + ++ N
Sbjct: 1536 TKHENFDIVASVIVNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTN 1595
Query: 1288 FKMRYYI-LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
++ Y + ++ +I F ++ G + ++ DRE Y + V A Q
Sbjct: 1596 GQVIYSLDARQSSEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATDQ-------- 1647
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
D ++ T +V V + DVNDN P+FT
Sbjct: 1648 ------GDRIQHAT--GTRVEVTVADVNDNPPRFT 1674
Score = 72.5 bits (170), Expect = 8e-11
Identities = 54/183 (29%), Positives = 83/183 (45%), Gaps = 13/183 (7%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P + A D D A L Y+++ F++DS G++ + LD + + NTF
Sbjct: 545 PLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALDYE-----ERNTFHF 599
Query: 275 QVQASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VQ L P A+ A V IE+ D+ND P F Y +++ G V+Q+ ATD
Sbjct: 600 TVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITPTYKGVKVIQINATD 659
Query: 333 KDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
D G N + + + F +DP +G ++V+N T L S +KV + S
Sbjct: 660 SDSGPNAKLLLSISEGNIGDKFKMDPTTGIISVQNVTQL----RSRYELKVRVSDGRFSS 715
Query: 391 VGT 393
V T
Sbjct: 716 VAT 718
Score = 71.3 bits (167), Expect = 2e-10
Identities = 82/330 (24%), Positives = 140/330 (42%), Gaps = 17/330 (5%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV--PFAVEERSGV 628
P F YE V + GT V QI +D E+N +++ LL + F ++ +G
Sbjct: 208 PQFSEKFYEVNVAEDTPPGTEVLQISASDRDEKNKLTFTLLSSTDPFSLRKFRLDPGTGT 267
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
+ + L + M+ + + ++ + N +V+V+D +P V
Sbjct: 268 LYTAETLD--HETMHHHILTVMVRDQDIPVKRNLVRVIVNVDDTNDNAPWFVGAPFSGRV 325
Query: 689 KENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
E++A G+A+ Q+ T G V L + T I + GTI K LDR+
Sbjct: 326 FESAAVGSAVLQV--TARDKDKGRNAEVVYSLESGNFANTFSID-PKLGTITVAKELDRD 382
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
+ Y +TV A N GV + V I + ++ P F + + E++ G+ +
Sbjct: 383 SKAQYELTVKASDN-GVPPLSTTAPVRIAVTVSDNAAPRFTEREFSADVSESAHPGSFVA 441
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
+ T + + +++F G FD++ N+GVV LD E Y L +
Sbjct: 442 L-----VTASSQ--SSVFYQIKAGNINNAFDINPNSGVV-VTQRPLDYETTAQYTLVIQG 493
Query: 868 RDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ GL + L++ + DENDN P F Q E
Sbjct: 494 TNMAGLGTNTTLLVHLKDENDNAPIFIQKE 523
Score = 71.3 bits (167), Expect = 2e-10
Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 16/232 (6%)
Query: 227 VGATLRYELISGNDRKLFSLDSVNGS--LFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
+ + Y + G+ F+++ + +F++K LD + + N ++L + AS +
Sbjct: 1706 INKQVNYFITGGDPLGQFAIEHIQNEWKVFVKKPLDREEKDN-----YLLNITAS---DG 1757
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
+ TA+A VE+++LD NDN P+ E Y+ S+ EN P G +LQV A+D D N + Y+
Sbjct: 1758 IFTAKATVEVKVLDANDNSPQCEKALYSESVPENSPAGRLILQVSASDADIRSNAQIFYE 1817
Query: 345 LDDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKW 403
L F+ID +G L + LDRE R K+ A + AD + +
Sbjct: 1818 LQGAGSELFTIDSDTGEL--KTLQPLDREEQEEHRFKMRAVDGGGRYCE--ADIHVVVED 1873
Query: 404 RRQPL-ETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
L + +A L T ++GT + D + N+ +LLD+ D
Sbjct: 1874 VNDNLPQFSADLYTVTVFENTEIGTYVAKLLANDVDVGPNSNIIYSLLDSAD 1925
Score = 71.3 bits (167), Expect = 2e-10
Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E++ +GT ++++ A D+ NG+I Y S F ++ R G
Sbjct: 1994 VSEDVSVGTQLLRVQAASRDTEANGEISYGIISG-------------NEHGLFSVDPRTG 2040
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V + L E+ E+ + + A DGG+ L+D +V + + DVND+ PVF + Y V
Sbjct: 2041 DIFVIQPLDYEASHEYYITVEATDGGSPPLSDMATVNINLTDVNDNRPVFSQDVYTAVVS 2100
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + V+A D D ++++ Y I + PF I G L V +LDRE E++
Sbjct: 2101 EDAELGKTVITVNAEDLDGPSHSHVRYSIVDGNQGSPFTIDSARGELKVAHQLDRERENR 2160
Score = 68.9 bits (161), Expect = 1e-09
Identities = 88/414 (21%), Positives = 181/414 (43%), Gaps = 40/414 (9%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ +G+ ++++ A D D G N ++ Y S + F I+ + G +
Sbjct: 327 ESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFA-------------NTFSIDPKLGTI 373
Query: 1002 IVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VA+ L +S ++ L + A D G L+ VR+ V ++ P F + ++ +V E+
Sbjct: 374 TVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPRFTEREFSADVSES 433
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + V A+ +++ Y I+ + + F+I+P +GV+ LD ET +Y
Sbjct: 434 AHPGSFVALVTASS-----QSSVFYQIKAGNINNAFDINPNSGVVVTQRPLDYETTAQYT 488
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLEWKHP-EADELSNHNFE 1174
L + + D NDN+P F F ++ P + L+ N
Sbjct: 489 LVIQGTN---MAGLGTNTTLLVHLKDENDNAPIFIQKEFRGVVSESAPVNSVVLTREN-- 543
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN-----LGL 1229
+ +++ A ++NA + + + FA++ I + G I + ++N + +
Sbjct: 544 TPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALDYEERNTFHFTVQV 603
Query: 1230 PSLSSTAILMVTVADVPDEV-EMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
L + T A+V EV +++D PVF + YE + V+++ +N T+ ++
Sbjct: 604 HDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITPTYKGVKVIQINATDS-DS 662
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
+L+ ++ +I F +DP G + + +++ YE+ VR ++S
Sbjct: 663 GPNAKLLLSISEGNIGDKFKMDPTTGIISVQNV--TQLRSRYELKVRVSDGRFS 714
Score = 64.9 bits (151), Expect = 2e-08
Identities = 103/429 (24%), Positives = 176/429 (41%), Gaps = 54/429 (12%)
Query: 1010 ESEFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ F + + G D ++ + V V+D ND+ P+F Y+ V+ ++ +V
Sbjct: 798 QDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQV 857
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET-EDKYILTVVARDNG 1126
A D D GQNA + Y ++ F+ISP +G +S+ +L +E+ +++ VVA+DNG
Sbjct: 858 TAVDRDMGQNAEIQYLLKEHQEF--FQISP-SGEISLKKKLQKESLNTDFVIVVVAQDNG 914
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE--WKHPEADELSNHNFESVMMIPVYKA 1184
K + E+ E H + +N E + VY
Sbjct: 915 NPALSAEVEVPVTVVNKAMPAFEKAFYTIEIPENIQLHTPVLHVQANNSEGPRI--VY-- 970
Query: 1185 TIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVAD 1244
TI E P K F+ DF G+I P S+ +T L +D
Sbjct: 971 TISEGDPF-----KQFS--IDF---NTGVIHVIQPLDFETHPAYKLSVRATDSLTGAHSD 1020
Query: 1245 VPDEVEMSD----KPVFISRYYELEIEENVNAPVELVSLNLTE-HYENFKMRYYILNEND 1299
V ++ + D PVF+S+ Y + E ++ ++ + N + ++ L E
Sbjct: 1021 VFVDIILEDVNDNAPVFLSKAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLVEEK 1080
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
+ F ID GT+ + D E +E+ VRA R +P +
Sbjct: 1081 GESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRA----VDRGVPAL------------ 1124
Query: 1360 TKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
+V V + + D+NDN+P+FT + + I AP G+ + Q++ AS
Sbjct: 1125 -SSEVIVTIDVTDLNDNAPEFT--QQTYNSTISELAPRGHFITQVQ--------ASDADS 1173
Query: 1420 ADTDELVFF 1428
+D D L+FF
Sbjct: 1174 SDKDNLLFF 1182
Score = 64.5 bits (150), Expect = 2e-08
Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 9/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELIS--GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + ++L+ G F++D G++ + LD + + L+
Sbjct: 1059 VDAKDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTGTISTAQLLDYE-----EIRQHELR 1113
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A P +++ V I++ DLNDN PEF YN +I E P G + QV A+D D
Sbjct: 1114 VRAVDRGVPALSSEVIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADS 1173
Query: 336 G--ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+N F + + FSID +G + + N + + +L + V
Sbjct: 1174 SDKDNLLFFFTSGNEDLNFSIDKHTGAILISNHRRVHMQPFYNLSVSV 1221
Score = 60.9 bits (141), Expect = 3e-07
Identities = 35/98 (35%), Positives = 53/98 (54%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ V V V D ND+ P F ++ V E+ + +V A D D G+NA + Y ++ +
Sbjct: 300 VRVIVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGN 359
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F I P G ++V ELDR+++ +Y LTV A DNG
Sbjct: 360 FANTFSIDPKLGTITVAKELDRDSKAQYELTVKASDNG 397
Score = 58.4 bits (135), Expect = 1e-06
Identities = 75/320 (23%), Positives = 127/320 (39%), Gaps = 31/320 (9%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIG 125
VR L + + V + +EDVNDN P+FL YH V E + G + + G
Sbjct: 1008 VRATDSLTGAHSDVFVDIILEDVNDNAPVFLSKAYHANVSEASVVGTRILQVDAKDSDTG 1067
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDV--------HYSIVSGNDDGHFALESS 177
+ + + D DRD + + H V D G AL S
Sbjct: 1068 NNQEVFFQLVEEKGESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPALSSE 1127
Query: 178 HKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
V++ V D + EF Q ++ + F + A D D L +
Sbjct: 1128 ---VIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLFFFT 1184
Query: 237 SGNDRKLFSLDSVNGSLFL--EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
SGN+ FS+D G++ + + + + +NL + +++ + + A V +
Sbjct: 1185 SGNEDLNFSIDKHTGAILISNHRRVHMQPFYNLSVS----------VSDGVFRSSAAVLV 1234
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAF 352
++ N + P F + + +VE+ V + ATD D+G G+ YQ+ D K F
Sbjct: 1235 TVIGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVNDFAKDKF 1294
Query: 353 SIDPRSGWLTVRNQTVLDRE 372
S++ T+ + LDRE
Sbjct: 1295 SVNENGEIFTLES---LDRE 1311
Score = 56.8 bits (131), Expect = 4e-06
Identities = 71/320 (22%), Positives = 133/320 (41%), Gaps = 25/320 (7%)
Query: 595 IRVNDAF-EQNDVS-YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ- 651
+R +DA +QN + Y ++ + FA++ +G I + L R + F
Sbjct: 548 VRASDADGDQNAMLIYQIVEPFAHNY-FAIDSNTGAIRITTALDYEERNTFHFTVQVHDL 606
Query: 652 --ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
N T+ V DVND V + + + + G + QI T+ S
Sbjct: 607 GIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATV--ITPTYKGVKVIQINATDSDS-- 662
Query: 710 GNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG 769
G L ++ ++ D + I + + + + R Y + V + G S
Sbjct: 663 --GPNAKLLLSISEGNIGDKFKMDPTTGIISVQNVT-QLRSRYELKV--RVSDGRFSS-- 715
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+ V I +++ +N F +Y+ F+ ENS +E K +I A ++ LF Y +
Sbjct: 716 VATVKINVKENKENKLKFTKESYKAFVQENS---SEKKTLEVIAAV-GNQVNEPLF-YNI 770
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--IMIGDEN 887
K+ F++ +GVV G DRE + +++ + G A ++ +M+ D N
Sbjct: 771 LNPDKK-FEISRTSGVVSTTGIPFDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDAN 829
Query: 888 DNKPEFNQIEENSKVRIHRE 907
DN+P F + ++ V++ E
Sbjct: 830 DNRPMFVNLPYHALVQMDAE 849
Score = 56.0 bits (129), Expect = 7e-06
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 14/177 (7%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A DQD G + Y L S +LF+++S G + KELD + + +
Sbjct: 1585 VRASDQDSGTNGQVIYSLDARQSSEEISELFAVNSETGWVTTLKELDRE-----KMQRYT 1639
Query: 274 LQVQASQLNNPLKTAQA-RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA-T 331
+ V A+ + ++ A RVE+ + D+NDN P F + Y ++ E+ P V+ +++ T
Sbjct: 1640 IAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGTVSEDDPPPSGVIAILSTT 1699
Query: 332 DKDQGE-NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D + N + Y + DP G F+I+ V + LDRE + + + A +
Sbjct: 1700 DADSEDINKQVNYFITGGDPLGQFAIEHIQNEWKVFVKKPLDREEKDNYLLNITASD 1756
Score = 54.8 bits (126), Expect = 2e-05
Identities = 70/292 (23%), Positives = 121/292 (41%), Gaps = 22/292 (7%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSLTIPLTVPRG 137
+VT+ + DVND P+F Y TV +TPT + + I + GP+ + L++ G
Sbjct: 618 NVTIEVTDVNDCPPVFSQKTYEATV--ITPTYKGVKVIQINATDSDSGPNAKLLLSISEG 675
Query: 138 LT--IFK-DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
FK D N Y + DG F+ ++ K + K
Sbjct: 676 NIGDKFKMDPTTGIISVQNVTQLRSRYELKVRVSDGRFSSVATVKINVKENKENKLKFTK 735
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
+ ++ + + K+ L E I A+ V L Y ++ N K F + +G +
Sbjct: 736 ESYKAFVQENSSE--KKTL--EVIAAVGNQ--VNEPLFYNIL--NPDKKFEISRTSG-VV 786
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
+ D E +TF + V+ ++ A + + + D NDN P F Y+
Sbjct: 787 STTGIPFDREAQ---DTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHAL 843
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
+ + G + QV A D+D G+N E Y L + + F I P SG ++++ +
Sbjct: 844 VQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEHQEFFQISP-SGEISLKKK 894
Score = 54.4 bits (125), Expect = 2e-05
Identities = 80/325 (24%), Positives = 128/325 (39%), Gaps = 37/325 (11%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
L+ + V + V D N+H P F + +Y NV E + ++ A+D D T
Sbjct: 190 LHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDEKNKLTFTLLS 249
Query: 1085 QPSDTDL-PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
L F + P TG L LD ET +ILTV+ RD D
Sbjct: 250 STDPFSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQ-DIPVKRNLVRVIVNVDD 308
Query: 1144 VNDNSPKFY-------AFDE------LLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
NDN+P F F+ +L+ + D+ N + + T +
Sbjct: 309 TNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFANTFSIDP 368
Query: 1191 PIGT-TVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV 1249
+GT TVAK D+ Y L + + G+P LS+TA + + V V
Sbjct: 369 KLGTITVAKELDRDSK--------AQYELTVKASDN--GVPPLSTTAPVRIAVT-----V 413
Query: 1250 EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVID 1309
+ P F R + ++ E+ + P V+L +T ++ + Y I N I F I+
Sbjct: 414 SDNAAPRFTEREFSADVSESAH-PGSFVAL-VTASSQS-SVFYQIKAGN---INNAFDIN 467
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVR 1334
P +G + R D E Y ++++
Sbjct: 468 PNSGVVVTQRPLDYETTAQYTLVIQ 492
Score = 54.0 bits (124), Expect = 3e-05
Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 24/177 (13%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G +L ++++ V D + +P F ++YE+ + E+ E++ ++ ++ E
Sbjct: 186 GTKALHHLLLVLIRVIDTNNH-----RPQFSEKFYEVNVAEDTPPGTEVLQISASDRDEK 240
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
K+ + +L+ D R F +DP GTLY + D E + + V Q
Sbjct: 241 NKLTFTLLSSTDPFSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQD-------- 292
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
PV ++ V+V+V + D NDN+P F P + +A G V+Q+
Sbjct: 293 -IPVKRNL--------VRVIVNVDDTNDNAPWFVGA--PFSGRVFESAAVGSAVLQV 338
Score = 51.2 bits (117), Expect = 2e-04
Identities = 79/330 (23%), Positives = 133/330 (40%), Gaps = 23/330 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G + L V + + D N++ P F + Y V V E TP G + + +
Sbjct: 186 GTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDEKNKLTF 245
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFA---LESSHKPVL--LLRKV 187
T+ F +R F D P T ++ H + PV L+R +
Sbjct: 246 TLLSSTDPFS-LRKFRLD-PGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVI 303
Query: 188 LDYDAGDKEFQLVIMA--SGKRIHKEILFPEPIH--AIDQDLGVGATLRYELISGNDRKL 243
++ D + + A SG+ + + A D+D G A + Y L SGN
Sbjct: 304 VNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFANT 363
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS+D G++ + KELD D++ + L V+AS P + A V I + ++
Sbjct: 364 FSIDPKLGTITVAKELDRDSKAQ-----YELTVKASDNGVPPLSTTAPVRIAVTVSDNAA 418
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P F ++ + E+ G V V A+ + + + + + AF I+P SG V
Sbjct: 419 PRFTEREFSADVSESAHPGSFVALVTASSQ---SSVFYQIKAGNINNAFDINPNSG--VV 473
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
Q LD E + + + + TN + +GT
Sbjct: 474 VTQRPLDYETTAQYTLVI--QGTNMAGLGT 501
Score = 48.0 bits (109), Expect = 0.002
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 11/119 (9%)
Query: 1017 ISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQ-------YTRRVLGKV 1067
I+ D G + SVRV V+ D ND+ P+F + Y + E + R + +V
Sbjct: 1 ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
A+D D G NA ++Y I+ D + F I P TG++S D ILT+ A DNG
Sbjct: 61 IASDRDDGPNAEISYSIEEGDENGKFFIEPKTGLVSSKKFSSAGEYD--ILTIKAVDNG 117
Score = 42.3 bits (95), Expect = 0.099
Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE--IKMDNIIK--ATDAD 818
GV + + +V + + DENDN P+F Y+ + E K E IK D + + A+D D
Sbjct: 7 GVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRVIASDRD 66
Query: 819 EGTNALFMYTL-FGEGKEMFDVDENTGVV 846
+G NA Y++ G+ F ++ TG+V
Sbjct: 67 DGPNAEISYSIEEGDENGKFFIEPKTGLV 95
Score = 36.7 bits (81), Expect = 4.9
Identities = 16/37 (43%), Positives = 22/37 (59%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
I A + V + ++DVNDN P+F PY V E P+G
Sbjct: 1543 IVASVIVNIQVKDVNDNKPVFESDPYEAVVVENLPSG 1579
>UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor
suppressor homolog 4; n=2; Danio rerio|Rep: PREDICTED:
similar to FAT tumor suppressor homolog 4 - Danio rerio
Length = 2572
Score = 147 bits (356), Expect = 2e-33
Identities = 244/1029 (23%), Positives = 430/1029 (41%), Gaps = 136/1029 (13%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ VE+ +LD NDN+PVF + +++ + ++ V A+D D G NG + Y +
Sbjct: 287 AYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLV--VSALDQDSGPNGQLEYAII 344
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + F IN TG + E +++L V+A+D+ P + + ++
Sbjct: 345 DGNK---ENSFNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLD 401
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY---E 615
V N P A V N +G +V ++ D D + + Y +
Sbjct: 402 VN----DNAPRFSKIFSAT----VPENAPVGFTVTRVTTTD----EDAGANAISRYSITD 449
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+PF + +G IT+ L+R + Y + A ++ ++ T+ T+ V D+ND
Sbjct: 450 ASLPFIIHPSTGDITISRPLNREDTDHYIAKVSA--HDSGWTVSTDVTIFVTDINDNAPR 507
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AE 734
K ++ + + + G+ + Q+ T+ + G + + I +Q T+ I +
Sbjct: 508 FSKPSY--YLDYPELTEIGSIVTQVSATDPDEGFN---GKIFYFIRSQ---TEYFRINSS 559
Query: 735 DGTIFTQKPLDREKR------DVYRMT-VIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G IF ++ L + +V R + ++ ++G+ V I + D NDNPP F
Sbjct: 560 SGEIFIKQQLRYQNSSGHNNINVNRHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTF 619
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVV 846
E +Y + ++ K+GT + +K T D+ FG E+ + +
Sbjct: 620 ESPSYFTPVTKSVKVGTRL-----LKVTAYDKKD--------FGLNSEIEYAISGGNSSN 666
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
KF LD++ + S +A DT ++ L+ + + N P + + + V+I
Sbjct: 667 KF---RLDKQTGSVTVASSLAADT----NKVYLLEITASDKGNPP----LSDRTTVKIAV 715
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG--LNG 964
+ + T F+ +N+ + V E + +GT I L+A D D +NG
Sbjct: 716 TEENHHTPEFS------QNQVTVTVS---------EALTVGTAIRTLSARDKDKDKQMNG 760
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDG 1022
I Y +S + D L F ++ + G + +A++L E++ + L +SA DG
Sbjct: 761 LITYNISSG--------NDDGL-----FSVHSQTGVLSLAKTLDYETKQKHELRVSATDG 807
Query: 1023 GNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
G + ++V + V DVND+ PVF Y V+E + + K++ATD D G NA +
Sbjct: 808 GWIAKTSYVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTTVVKMNATDKDSGSNALM 867
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y IQ SD+DL F I P TG+++ G LD E + Y LTV A N
Sbjct: 868 AYVIQSSDSDL-FIIDPNTGIITTQGFLDYEAKQVYHLTVKA-FNVPDEERCSFAYVNIQ 925
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF 1200
N+ P+F + E+S + ++ V+ A+ + G +F
Sbjct: 926 LKGANEYVPRFVSKQYYF--------EISEAAPKGTVVGEVF-ASDRDLGEDGVVYYLIF 976
Query: 1201 ANDTD---FIGNGNGLILYS-LPQRKNQQNLGLPSLSSTAILMVTVADVPDEV------- 1249
I G I S R+ ++ + L L+ A + AD+ DEV
Sbjct: 977 GRSRKRGFSINKKTGQIYVSGSLDREKEEKISLKVLAKNA-GSIRGADI-DEVLVNITVL 1034
Query: 1250 EMSDKPVFISRYYELEIEENVN--APVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV 1307
+ +D PVF Y++++ E ++ V VS ++ ++ Y + N R TF
Sbjct: 1035 DANDPPVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWSRFTYAIAANHE--RNTFT 1092
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV 1367
I+P+ G + + DRE Y + + A I V LE + +V
Sbjct: 1093 INPQTGQVSVASELDRETVPVYNLTILAVDSGSPAATGSAILIV---TLEDINDNGPTLV 1149
Query: 1368 VRIKDVNDN----SPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRADTD 1423
+V +N +P T +R A P PF Y ++ GA + T S T T
Sbjct: 1150 TTYGEVMENQRAGTPVMTLSSRDPDLA-PNQGPFTYSLVS-TGAASSYFTISPTGELTTS 1207
Query: 1424 ELVFFERLS 1432
V E++S
Sbjct: 1208 REVDREQIS 1216
Score = 128 bits (309), Expect = 1e-27
Identities = 142/543 (26%), Positives = 234/543 (43%), Gaps = 50/543 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S+V V + + D NDN PVF P + ++ N GT + K+ A D D G N ++ Y +Q
Sbjct: 814 SYVTVNIQVTDVNDNPPVFDPVEYFPV-VQENVPSGTTVVKMNATDKDSGSNALMAYVIQ 872
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
+ + F I+PNTG ++ E + + L V+A + P E R S A V I+
Sbjct: 873 SSD----SDLFIIDPNTGIITTQGFLDYEAKQVYHLTVKAFNV---PDEERCSFAYVNIQ 925
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEG 617
+ KG +P F+ Y F + GT VG++ +D ++ V Y L+ G
Sbjct: 926 L----KGANEYVPRFVSKQYYFEISEAAPKGTVVGEVFASDRDLGEDGVVYYLIFGRSRK 981
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F++ +++G I V L R + +A N + A + V VN + +
Sbjct: 982 RGFSINKKTGQIYVSGSLDREKEEKISLKVLA----KNAGSIRGADIDEVLVN----ITV 1033
Query: 678 KGAHSPIIF-------HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
A+ P +F V E + + S + + + AN + T I
Sbjct: 1034 LDANDPPVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWSRFTYAIAANHERNTFTI 1093
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G + LDRE VY +T++A + G + G + + +ED NDN P
Sbjct: 1094 N-PQTGQVSVASELDRETVPVYNLTILA-VDSGSPAATGSAILIVTLEDINDNGPTL--V 1149
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEG-KEMFDVDENTGVVKF 848
T G +MEN + GT + + + D D N F Y+L G + TG +
Sbjct: 1150 TTYGEVMENQRAGTPVM---TLSSRDPDLAPNQGPFTYSLVSTGAASSYFTISPTGELT- 1205
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+DRE+ + LS++ +D+G +SS + I + D+NDN E +E + +H
Sbjct: 1206 TSREVDREQISDFYLSVLIKDSGIPQMSSTGTVHIKVNDQNDNPSESRSVE----IYVHY 1261
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQ--LGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
N G ++ VKP++ D Q L P + +IP GT + N+ D +
Sbjct: 1262 FG--NMFPGGSLGVVKPQDPDIQDTFQCSLTPPAALLFSIPTGTCDLISNSRSTDGTFDL 1319
Query: 965 QIR 967
+R
Sbjct: 1320 SVR 1322
Score = 121 bits (292), Expect = 1e-25
Identities = 127/472 (26%), Positives = 211/472 (44%), Gaps = 41/472 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD-PDLGQNGMVLY 497
LMS V + ++D+NDN P F S Y + + KVGT + KV A D D G N + Y
Sbjct: 599 LMSETTVMINVVDSNDNPPTF-ESPSYFTPVTKSVKVGTRLLKVTAYDKKDFGLNSEIEY 657
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
+ S ++ F+++ TG+V+VA S + + L + ASD+ P R ++ +
Sbjct: 658 AI---SGGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIA 714
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYDLL 611
E T P+F V + +GT++ + D + ++Y++
Sbjct: 715 VTEENHHT-------PEFSQNQVTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNIS 767
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDV 669
G ++G+ F+V ++GV+++ L + ++ A A S VT + V DV
Sbjct: 768 SGNDDGL-FSVHSQTGVLSLAKTLDYETKQKHELRVSATDGGWIAKTSYVT-VNIQVTDV 825
Query: 670 NDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND V + P+ V+EN +G + ++ T+ S G+ + + D
Sbjct: 826 NDNPPVFDPVEYFPV---VQENVPSGTTVVKMNATDKDS----GSNALMAYVIQSSDSDL 878
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I G I TQ LD E + VY +TV A FN V I ++ N+ P F
Sbjct: 879 FIIDPNTGIITTQGFLDYEAKQVYHLTVKA-FNVPDEERCSFAYVNIQLKGANEYVPRFV 937
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVK 847
Y I E + GT + + A+D D G + + Y +FG K F +++ TG +
Sbjct: 938 SKQYYFEISEAAPKGTVV---GEVFASDRDLGEDGVVYYLIFGRSRKRGFSINKKTGQI- 993
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLS----SEAELIIMIGDENDNKPEFNQ 895
++ SLDREK+ L ++A++ G + E + I + D ND P F Q
Sbjct: 994 YVSGSLDREKEEKISLKVLAKNAGSIRGADIDEVLVNITVLDAND-PPVFTQ 1044
Score = 97.1 bits (231), Expect = 3e-18
Identities = 111/458 (24%), Positives = 180/458 (39%), Gaps = 30/458 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V + D NDN P F + Y + ++ G+++ V D D G N + Y
Sbjct: 82 LSSSATVSVVVADINDNPPRF-HHHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYS 140
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + + FKI+P G ++ +E V D NP + VT+
Sbjct: 141 LTGRN----SEKFKIDPIRGAITASEKLTGSSEVTFTVHVKDGGTNP---KTDSTTVTVR 193
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
G D P F N T V ++ + +SY + G +
Sbjct: 194 FVTG-----GDFPHIKLKDKAFTFPENQPTNTIVTKV-TGSSPRAGPLSYYIASGNLDNA 247
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLL 677
F +++ SG +++ L N Y A + S + V+DVND V
Sbjct: 248 -FHIDQLSGELSIRKPLDYENIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVNDNHPVF- 305
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
P + EN + + + + S G + + I + G
Sbjct: 306 --EQEPFHAEILENLSPQRVLVVSALDQDS---GPNGQLEYAIIDGNKENSFNINRATGE 360
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T +PLDREK Y + V A ++G+ + +V I + D NDN P F + +
Sbjct: 361 IRTTRPLDREKVAQYSLRVKAT-DRGMPPKSTAVKVLISVLDVNDNAPRFS-KIFSATVP 418
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN+ +G + + TD D G NA+ Y++ + F + +TG + I L+RE
Sbjct: 419 ENAPVGFTVTR---VTTTDEDAGANAISRYSI-TDASLPFIIHPSTGDIT-ISRPLNRED 473
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
Y + A D+G S ++ I + D NDN P F++
Sbjct: 474 TDHYIAKVSAHDSGWTVS-TDVTIFVTDINDNAPRFSK 510
Score = 93.5 bits (222), Expect = 4e-17
Identities = 115/444 (25%), Positives = 191/444 (43%), Gaps = 46/444 (10%)
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE 524
+ ++ +A GT + + + D D+G NG++ Y L F INP+TG + +
Sbjct: 3 FHTTIPEDAPTGTDVLLLNSSDSDVGLNGVISYSLSGGDG-----QFSINPSTGLIITSS 57
Query: 525 SPILEGR--HALFVEASD--QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
E R + L V ASD QP P +++VV ++ + P P F PY
Sbjct: 58 LLDRETRASYQLLVVASDGGQPT-PLSSSATVSVVVADIN-----DNP--PRFHHHPYVT 109
Query: 581 WVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRY 638
+ ++ G+ V + V D + + + Y L E F ++ G IT + L+
Sbjct: 110 HIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSE--KFKIDPIRGAITASEKLTGS 167
Query: 639 NRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
+ + N T TV V D + LK F EN
Sbjct: 168 SEVTFTVHVKDGGTNPKTDSTT-VTVRFVTGGDFPHIKLKDK----AFTFPEN------- 215
Query: 699 QIFHTNMSSIYGNG--TGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMT 755
Q +T ++ + G+ G + + IA+ ++ + I + G + +KPLD E + Y +
Sbjct: 216 QPTNTIVTKVTGSSPRAGPLSYYIASG-NLDNAFHIDQLSGELSIRKPLDYENIEKYVLW 274
Query: 756 VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
+ A ++G + +V I + D NDN PVFE + I+EN + ++ A
Sbjct: 275 IEAR-DQGFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVL----VVSAL 329
Query: 816 DADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--G 872
D D G N Y + KE F+++ TG ++ LDREK Y L + A D G
Sbjct: 330 DQDSGPNGQLEYAIIDGNKENSFNINRATGEIR-TTRPLDREKVAQYSLRVKATDRGMPP 388
Query: 873 LSSEAELIIMIGDENDNKPEFNQI 896
S+ +++I + D NDN P F++I
Sbjct: 389 KSTAVKVLISVLDVNDNAPRFSKI 412
Score = 85.8 bits (203), Expect = 8e-15
Identities = 57/163 (34%), Positives = 83/163 (50%), Gaps = 8/163 (4%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D+D + + Y + SGND LFS+ S G L L K LD + + + L+V A+
Sbjct: 753 DKDKQMNGLITYNISSGNDDGLFSVHSQTGVLSLAKTLDYETKQKHE-----LRVSATDG 807
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
KT+ V I++ D+NDN P F+ Y + EN+P+G +V+++ ATDKD G N
Sbjct: 808 GWIAKTSYVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTTVVKMNATDKDSGSNALM 867
Query: 342 TYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
Y + F IDP +G +T Q LD EA + V A
Sbjct: 868 AYVIQSSDSDLFIIDPNTGIIT--TQGFLDYEAKQVYHLTVKA 908
Score = 83.0 bits (196), Expect = 6e-14
Identities = 84/354 (23%), Positives = 154/354 (43%), Gaps = 22/354 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
DE+ SF V + L AN+ P FV S Y F + A GTV+G+V A D DLG++G+V
Sbjct: 913 DEERCSFAYVNIQLKGANEYVPRFV-SKQYYFEISEAAPKGTVVGEVFASDRDLGEDGVV 971
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y + S F IN TG + V+ S E + ++ + A S R + V
Sbjct: 972 YYLIFGRSR---KRGFSINKKTGQIYVSGSLDREKEEKISLKVLAKNAG-SIRGADIDEV 1027
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF---EQNDVSYDLLH 612
+ +T N P P F Y+ V + G V + D+ + +Y +
Sbjct: 1028 LVNIT-VLDANDP--PVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWSRFTYAIAA 1084
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND- 671
+E F + ++G ++V +L R P+Y+ +A+ + T + + +V + D
Sbjct: 1085 NHERNT-FTINPQTGQVSVASELDRETVPVYNLTILAVDSGS--PAATGSAILIVTLEDI 1141
Query: 672 -ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ G L + + ++ AG + + ++ G + + + +
Sbjct: 1142 NDNGPTLVTTYGEV---MENQRAGTPVMTL--SSRDPDLAPNQGPFTYSLVSTGAASSYF 1196
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
I+ G + T + +DRE+ + ++V+ + + G+ + V I + D+NDNP
Sbjct: 1197 TISPTGELTTSREVDREQISDFYLSVLIK-DSGIPQMSSTGTVHIKVNDQNDNP 1249
Score = 81.4 bits (192), Expect = 2e-13
Identities = 57/154 (37%), Positives = 87/154 (56%), Gaps = 12/154 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L Y + SGN F +D ++G L + K LD + N++ +VL ++A P +A
Sbjct: 235 LSYYIASGNLDNAFHIDQLSGELSIRKPLDYE---NIEK--YVLWIEARDQGFPPYSAYE 289
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--P 348
+VEI +LD+NDN P FE + ++ I+ENL + VL V A D+D G NG+ Y + D
Sbjct: 290 KVEIAVLDVNDNHPVFEQEPFHAEILENL-SPQRVLVVSALDQDSGPNGQLEYAIIDGNK 348
Query: 349 KGAFSIDPRSGWLTVRNQTVLDRE--AHSSLRMK 380
+ +F+I+ +G +R LDRE A SLR+K
Sbjct: 349 ENSFNINRATG--EIRTTRPLDREKVAQYSLRVK 380
Score = 81.0 bits (191), Expect = 2e-13
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 65/453 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IP + G+ + + D DSG N Q+ Y F I+ G
Sbjct: 111 IPASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRN--------------SEKFKIDPIRG 156
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVND-HFPVFKKTWYNFNVEEAQ 1058
+ + L SE + DGG S V V+ V FP K F E Q
Sbjct: 157 AITASEKLTGSSEVTFTVHVKDGGTNPKTDSTTVTVRFVTGGDFPHIKLKDKAFTFPENQ 216
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
T ++ KV + G L+Y+I + D F I L+G LS+ LD E +KY+L
Sbjct: 217 PTNTIVTKVTGSSPRAGP---LSYYIASGNLDNAFHIDQLSGELSIRKPLDYENIEKYVL 273
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
+ ARD G DVNDN P F E + A+ L N + + V++
Sbjct: 274 WIEARDQG-FPPYSAYEKVEIAVLDVNDNHPVF-------EQEPFHAEILENLSPQRVLV 325
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL-------G 1228
+ N + + ++ I G I + P ++ Q +L G
Sbjct: 326 VSALDQDSGPNGQLEYAIIDGNKENSFNINRATGEIRTTRPLDREKVAQYSLRVKATDRG 385
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
+P S+ ++++V DV D + P F S+ + + E NAPV +T E+
Sbjct: 386 MPPKSTAVKVLISVLDVND-----NAPRF-SKIFSATVPE--NAPVGFTVTRVTTTDEDA 437
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
I + TD F+I P G + + R +RE D Y V A ++
Sbjct: 438 GAN-AISRYSITDASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSGWT------- 489
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
V+ D V + + D+NDN+P+F+
Sbjct: 490 --VSTD-----------VTIFVTDINDNAPRFS 509
Score = 72.9 bits (171), Expect = 6e-11
Identities = 78/326 (23%), Positives = 140/326 (42%), Gaps = 36/326 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-----------EKAFIFLIAPIGPSLTIP 131
VT+++ D+NDN P F Y++ ELT G ++ F I S T
Sbjct: 494 VTIFVTDINDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEY 553
Query: 132 LTVPRG---LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+ + I + +R + N N + H IV+ +D G L S ++ V+
Sbjct: 554 FRINSSSGEIFIKQQLRYQNSSGHNNINVNRHSFIVTASDRGIKPLMSE---TTVMINVV 610
Query: 189 DYDAGDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRKL 243
D + F+ + ++ +L + A D+ D G+ + + Y + GN
Sbjct: 611 DSNDNPPTFESPSYFTPVTKSVKVGTRLL---KVTAYDKKDFGLNSEIEYAISGGNSSNK 667
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F LD GS+ + L D ++L++ AS NP + + V+I + + N +
Sbjct: 668 FRLDKQTGSVTVASSLAADTN-----KVYLLEITASDKGNPPLSDRTTVKIAVTEENHHT 722
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQLD--DPKGAFSIDPRSG 359
PEF + +++ E L G ++ + A DKD+ + NG TY + + G FS+ ++G
Sbjct: 723 PEFSQNQVTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFSVHSQTG 782
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE 385
L++ LD E ++V A +
Sbjct: 783 VLSLAK--TLDYETKQKHELRVSATD 806
Score = 72.5 bits (170), Expect = 8e-11
Identities = 79/303 (26%), Positives = 118/303 (38%), Gaps = 24/303 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTV-DELTPTGEKAFIFLIAPIGPSLTIP 131
G SAY V + + DVNDN P+F P+H + + L+P L GP+ +
Sbjct: 281 GFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLVVSALDQDSGPNGQLE 340
Query: 132 LTVPRGL--TIFKDIRAFDRDKPNTP---NSDVHYSI-VSGNDDGHFALESSHKPVLLLR 185
+ G F RA + P YS+ V D G + V +L
Sbjct: 341 YAIIDGNKENSFNINRATGEIRTTRPLDREKVAQYSLRVKATDRG---MPPKSTAVKVLI 397
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL-F 244
VLD + F + A+ + D+D G A RY + D L F
Sbjct: 398 SVLDVNDNAPRFSKIFSATVPENAPVGFTVTRVTTTDEDAGANAISRYSI---TDASLPF 454
Query: 245 SLDSVNGSLFLEKELDL-DAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
+ G + + + L+ D +H ++ +V A T V I + D+NDN
Sbjct: 455 IIHPSTGDITISRPLNREDTDH------YIAKVSAHDSG---WTVSTDVTIFVTDINDNA 505
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P F Y + E G V QV ATD D+G NG+ Y + F I+ SG + +
Sbjct: 506 PRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSSGEIFI 565
Query: 364 RNQ 366
+ Q
Sbjct: 566 KQQ 568
Score = 71.7 bits (168), Expect = 1e-10
Identities = 58/192 (30%), Positives = 93/192 (48%), Gaps = 23/192 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ P GT ++ LN+ D D GLNG I Y + D F IN G
Sbjct: 7 IPEDAPTGTDVLLLNSSDSDVGLNGVISYSLSG----------GDG-----QFSINPSTG 51
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+I + L E+ ++L + A DGG L+ + +V V V D+ND+ P F Y ++
Sbjct: 52 LIITSSLLDRETRASYQLLVVASDGGQPTPLSSSATVSVVVADINDNPPRFHHHPYVTHI 111
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+ T ++ V TD D G N+ L Y + +++ F+I P+ G ++ + +L +E
Sbjct: 112 PASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSE-KFKIDPIRGAITASEKLTGSSEV 170
Query: 1115 KYILTVVARDNG 1126
+ TV +D G
Sbjct: 171 TF--TVHVKDGG 180
Score = 70.9 bits (166), Expect = 2e-10
Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 11/181 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+D G A + Y +I +D LF +D G + + LD +A+ + L V+
Sbjct: 854 MNATDKDSGSNALMAY-VIQSSDSDLFIIDPNTGIITTQGFLDYEAKQ-----VYHLTVK 907
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + + + A V I+L N+ +P F Y I E P G V +V A+D+D GE
Sbjct: 908 AFNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEISEAAPKGTVVGEVFASDRDLGE 967
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
+G Y + K FSI+ ++G + V LDRE + +KV AK S+ G
Sbjct: 968 DGVVYYLIFGRSRKRGFSINKKTGQIYVSGS--LDREKEEKISLKVLAKNAG-SIRGADI 1024
Query: 396 D 396
D
Sbjct: 1025 D 1025
Score = 63.3 bits (147), Expect = 5e-08
Identities = 52/181 (28%), Positives = 88/181 (48%), Gaps = 12/181 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+DLG + Y LI G RK FS++ G +++ LD + E + VL
Sbjct: 958 VFASDRDLGEDGVVYY-LIFGRSRKRGFSINKKTGQIYVSGSLDREKEEKISLK--VLAK 1014
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A + + V I +LD ND P F + Y++ + E L G V V A D D
Sbjct: 1015 NAGSIRGA-DIDEVLVNITVLDANDP-PVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSV 1072
Query: 337 EN-GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVG 392
+ FTY + + + F+I+P++G ++V ++ LDRE + + A ++ +P+ G
Sbjct: 1073 PSWSRFTYAIAANHERNTFTINPQTGQVSVASE--LDRETVPVYNLTILAVDSGSPAATG 1130
Query: 393 T 393
+
Sbjct: 1131 S 1131
Score = 60.9 bits (141), Expect = 3e-07
Identities = 51/178 (28%), Positives = 76/178 (42%), Gaps = 11/178 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+++ D D+G+ + Y L SG D + FS++ G + LD + + Q L V
Sbjct: 20 LNSSDSDVGLNGVISYSL-SGGDGQ-FSINPSTGLIITSSLLDRETRASYQ-----LLVV 72
Query: 278 ASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS P ++ A V + + D+NDN P F Y I + G V V TD+D G
Sbjct: 73 ASDGGQPTPLSSSATVSVVVADINDNPPRFHHHPYVTHIPASTSTGSLVFAVTVTDEDSG 132
Query: 337 ENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
N + Y L F IDP G +T + E ++ +K TNP T
Sbjct: 133 SNSQLHYSLTGRNSEKFKIDPIRGAITASEKLTGSSEVTFTVHVK--DGGTNPKTDST 188
Score = 58.0 bits (134), Expect = 2e-06
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
++++D+D G N ++Y + D F I+P TG++ + LDRET Y L VVA D G
Sbjct: 20 LNSSDSDVGLNGVISYSLSGGDGQ--FSINPSTGLIITSSLLDRETRASYQLLVVASDGG 77
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFY 1152
D+NDN P+F+
Sbjct: 78 QPTPLSSSATVSVVVADINDNPPRFH 103
Score = 50.4 bits (115), Expect = 4e-04
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
++ +I E+ P G VL + ++D D G NG +Y L G FSI+P +G + ++LD
Sbjct: 3 FHTTIPEDAPTGTDVLLLNSSDSDVGLNGVISYSLSGGDGQFSINPSTG--LIITSSLLD 60
Query: 371 REAHSSLRMKVYAKE 385
RE +S ++ V A +
Sbjct: 61 RETRASYQLLVVASD 75
Score = 49.6 bits (113), Expect = 6e-04
Identities = 43/141 (30%), Positives = 67/141 (47%), Gaps = 9/141 (6%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F IN + G V VA L E+ + L I A+D G+ + + V ++D+ND+ P
Sbjct: 1091 FTINPQTGQVSVASELDRETVPVYNLTILAVDSGSPAATGSAILIVTLEDINDNGPTLVT 1150
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTY-FIQPSDTDLPFEISPLTGVLSVN 1105
T+ V E Q + + + D D N TY + F ISP TG L+ +
Sbjct: 1151 TYGE--VMENQRAGTPVMTLSSRDPDLAPNQGPFTYSLVSTGAASSYFTISP-TGELTTS 1207
Query: 1106 GELDRETEDKYILTVVARDNG 1126
E+DRE + L+V+ +D+G
Sbjct: 1208 REVDREQISDFYLSVLIKDSG 1228
Score = 47.2 bits (107), Expect = 0.003
Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 130 IPLTVPRGLTIFKDIR---AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
+ +TV LT+ IR A D+DK N + Y+I SGNDDG F++ S VL L K
Sbjct: 730 VTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFSVH-SQTGVLSLAK 788
Query: 187 VLDYDAGDKEFQLVIMASGKRIHK 210
LDY+ K V G I K
Sbjct: 789 TLDYETKQKHELRVSATDGGWIAK 812
Score = 35.9 bits (79), Expect = 8.6
Identities = 14/36 (38%), Positives = 22/36 (61%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
++Y++V + + DVNDN P+F Y V E P+G
Sbjct: 813 TSYVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSG 848
>UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n=1;
Danio rerio|Rep: UPI00015A7221 UniRef100 entry - Danio
rerio
Length = 3995
Score = 147 bits (356), Expect = 2e-33
Identities = 193/761 (25%), Positives = 340/761 (44%), Gaps = 73/761 (9%)
Query: 161 YSIVSGND-DGH----FALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP 215
YS+V+GN D + FA++ V+L + D++ K +++ ++A G +
Sbjct: 2709 YSLVNGNTLDSNKELSFAIDKDGGTVVLQNNI-DHEK-TKMYKIDVIAQGNHNGTNVASL 2766
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN-TFVL 274
+H QD+ + + K F +++ + + DA+ N+ ++ L
Sbjct: 2767 VSVHIEVQDVNDNKPM----FEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYTL 2822
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN--LPNGFSVLQVMATD 332
+ ++ + + I L D+ + F+ ++ L SVL V T
Sbjct: 2823 EPESDDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVL-VEVTL 2881
Query: 333 KDQGENG-EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV-YAKETNPSV 390
D+ +N +FT +L +G+ + R G V T D++ + R V Y + +P
Sbjct: 2882 TDENDNPPQFTEELY--QGSILENSRPGENIV-TLTTADKDVSAENRQIVCYITDGDP-- 2936
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
+G F+ + +W + + +PL++ DK K I D + + NVEV +L
Sbjct: 2937 LGQFSVTAVGEEWT---VISKSPLDRED---KDKYTLK---IIATDGRFQTSANVEVHVL 2987
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN+P F Y ++ N+ G VI K+ A DPD+G NG V + L +
Sbjct: 2988 DLNDNSP-FCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGPN----ADK 3042
Query: 511 FKINPNTG---TVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F ++P TG T++V + E + L V+A+D + +L V + +
Sbjct: 3043 FHLDPKTGELFTLAVLDRE-REKEYDLVVKATDGGGRSCQADVTLMVQDMN-------DN 3094
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEER 625
P P F + YE V N I T + I D ++V Y L G + G F+++E
Sbjct: 3095 P--PQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSL-QGADSGF-FSLDEI 3150
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVNDERGVLLKGAHSP 683
SGV+ + L+ + Y+ + A + + A TVHVV ++D + + L +S
Sbjct: 3151 SGVLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSV 3210
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAEDGTIFTQ 741
I + + G+ + ++S++ + T N VR+ I + + + G + +
Sbjct: 3211 QI--AESSQVGSEV-----ISVSALTKDATENEPVRYSIISGNEDGRFMINPVTGLLSVK 3263
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LD E+ Y ++V K ++S I V I I D NDNPPVF ++Y I E+
Sbjct: 3264 AALDFERCREYYLSVEGARGKPLLSD--IAMVIINITDVNDNPPVFNRSSYSTVIPEDIS 3321
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
G +M ++A D D N +Y++ G+ K+ F +D TG + + LDRE+
Sbjct: 3322 PG---EMALQVRAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFIT-LRSMLDREEITH 3377
Query: 861 YKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEEN 899
Y L++ A D G LSS ++ + + D NDN P F++I +
Sbjct: 3378 YSLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHS 3418
Score = 145 bits (352), Expect = 7e-33
Identities = 132/480 (27%), Positives = 220/480 (45%), Gaps = 42/480 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ F V++ L D NDN P F S Y+ S++S G+ + ++ A D D G+N V Y +
Sbjct: 2551 VGFCTVKIILTDENDNVPQFKASE-YDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTV 2609
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI-LEGRHALF-VEASDQ--PANPSERRYSLAVV 555
+ +T ++NP TG VSV ES + LE + F V+A D P S + VV
Sbjct: 2610 EEADEVT-EDIIEVNPFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVV 2668
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY- 614
E+ +P F Y F ++ IG +G ++ DA + Y L++G
Sbjct: 2669 PPEII---------LPRFTEPLYSFSASEDLPIGYEIGTVKA-DA--DMPLIYSLVNGNT 2716
Query: 615 ---EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDV 669
+ + FA+++ G + + +++ MY + +A + ++ + +VH V DV
Sbjct: 2717 LDSNKELSFAIDKDGGTVVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDV 2776
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTD 728
ND + + + F + +G + Q+ + + N G V + + + D + D
Sbjct: 2777 NDNKPMFEADTYKA--FLAENLPSGTTVIQVTANDADA---NINGEVSYTLEPESDDIGD 2831
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
AI ++ G I T K D E + ++R V+A + + + V + + DENDNPP F
Sbjct: 2832 MFAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQF 2891
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA----LFMYTLFGEGKEMFDVDENT 843
Y+G I+ENS+ G +NI+ T AD+ +A + Y G+ F V
Sbjct: 2892 TEELYQGSILENSRPG-----ENIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVG 2946
Query: 844 GVVKFIGDS-LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
I S LDRE K Y L ++A D G + A + + + D NDN P Q++ V
Sbjct: 2947 EEWTVISKSPLDREDKDKYTLKIIATD-GRFQTSANVEVHVLDLNDNSPFCEQLQYTEAV 3005
Score = 144 bits (349), Expect = 2e-32
Identities = 203/769 (26%), Positives = 312/769 (40%), Gaps = 89/769 (11%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
L+ N EKT D + N + S V+V + + D NDN P+F ++ Y+
Sbjct: 2736 LQNNIDHEKTKMYKIDVIAQGNHN----GTNVASLVSVHIEVQDVNDNKPMF-EADTYKA 2790
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
+ N GT + +V A D D NG V Y L+ S+ I F I+ TG ++ +
Sbjct: 2791 FLAENLPSGTTVIQVTANDADANINGEVSYTLEPESD-DIGDMFAIDSQTGWITTLKEAD 2849
Query: 528 LEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + H FV A+D + A V +EVT + + P P F Y+ + N
Sbjct: 2850 SETKQLHRFFVVATDH----GDALKQSASVLVEVTLTDENDNP--PQFTEELYQGSILEN 2903
Query: 586 VGIGTSVGQIRVND---AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDD--LSRYNR 640
G ++ + D + E + + G G F+V TV+ L R ++
Sbjct: 2904 SRPGENIVTLTTADKDVSAENRQIVCYITDGDPLG-QFSVTAVGEEWTVISKSPLDREDK 2962
Query: 641 PMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
Y + +A S N VHV+D+ND + ++ + ENS+ + I
Sbjct: 2963 DKYTLKIIATDGRFQTS--ANVEVHVLDLNDNSPFCEQLQYTEAVM---ENSSSGKV--I 3015
Query: 701 FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ S G V F + D + + G +FT LDRE+ Y + V A
Sbjct: 3016 LKISASDPDIGTNGQVSFTLHGPN--ADKFHLDPKTGELFTLAVLDREREKEYDLVVKAT 3073
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
G A VT+ ++D NDNPP F + YE + +N+ I T I +I A D D
Sbjct: 3074 DGGGRSCQA---DVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIA---VIYAKDPDT 3127
Query: 820 GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSE 876
G N+ Y+L G F +DE +GV++ + SL E K Y++ + A D G L S
Sbjct: 3128 GINSEVRYSLQGADSGFFSLDEISGVLR-LERSLADETKSTYEMKVKATDRGLPRHLFSF 3186
Query: 877 AELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGP 936
A + + + +D +P F + V+I +++ G +I V K A
Sbjct: 3187 AMITVHVVILSDYQPLF--LSSEYSVQIAESSQV----GSEVISVSALTKDA-------- 3232
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
EN P+ +II SG N R+ N + K + D + Y++ E
Sbjct: 3233 ----TENEPVRYSII--------SG-NEDGRFMINPVTGLLSVKAALDFERCREYYLSVE 3279
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
AR P S+ + I ++ ++NDN V F ++ Y+ + E
Sbjct: 3280 G------ARGKPLLSDIAMVI--INITDVNDNPPV-------------FNRSSYSTVIPE 3318
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ +V A D D N + Y I D F I P TG +++ LDRE Y
Sbjct: 3319 DISPGEMALQVRAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHY 3378
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
LTV A D G DVNDN P F + L + EA
Sbjct: 3379 SLTVQAADEG-DPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEA 3426
Score = 142 bits (345), Expect = 5e-32
Identities = 142/476 (29%), Positives = 219/476 (46%), Gaps = 34/476 (7%)
Query: 431 NIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
NI YD Q ++ + V +LDANDN P+F S Y ++ N +V I KV AVD
Sbjct: 781 NITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSR-YVVTIPENTEVDKSIFKVNAVDF 839
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP 545
DL NG Y L T T F+I +TG V V E R+ L +EA DQ A P
Sbjct: 840 DLDNNGAFKYSL-----FTFTDLFQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQ-AKP 893
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
+ +S V + V N P F+ Y+ V +V GT + + D ++
Sbjct: 894 DPQLFSFTDVVV-VLEDINDNP---PKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESG 949
Query: 606 --VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA- 662
+SY+L + E G F ++ +G +T+ +L R Y+ A+ S+ ++
Sbjct: 950 GVISYNLKNS-ESGT-FFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCF 1007
Query: 663 -TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ V+DVN+ L G +++ G ++ + T + + G G VR+ I
Sbjct: 1008 IEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSV--LTLTAVDNDLGR-DGVVRYYIH 1064
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ + E G I T LDRE Y +TV A+ + G I +V I + D N
Sbjct: 1065 DGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAK-DLGTIPLVSWTEVYIEVWDIN 1123
Query: 782 DNPPVFEHATYEGFIMEN-SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
DNPP Y G + EN K + +K + ATD D+ + + + + F +D
Sbjct: 1124 DNPPELSQPVYFGSVQENLPKDKSVLK----VSATDMDKSSEGKLAFQILDSQRIYFTID 1179
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
TGV+ + SLDRE+K + + ++ D G LSS A ++I + DENDN P+F+
Sbjct: 1180 SKTGVISTL-SSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFS 1234
Score = 142 bits (344), Expect = 7e-32
Identities = 139/467 (29%), Positives = 219/467 (46%), Gaps = 39/467 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
VN+++T + N +P F N+YE + NA+VGT + ++ A+DPD G G V Y +
Sbjct: 2452 VNIDMT--NGNKYSPYFT-QNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTI--- 2505
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
N F IN + G + V P+ + V A A R V I +T
Sbjct: 2506 INKLADEKFAINED-GQI-VTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIILT-- 2561
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYE--EGV 618
++P F + Y+ + S V G+ V QI DA E DV+Y + E E +
Sbjct: 2562 --DENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDI 2619
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
V +GV++V + L +++F+ A ++ ++ V V V E ++L
Sbjct: 2620 -IEVNPFTGVVSVKESLVGLENKIFNFKVKA-RDGGFPFYNSSVPVQVKVVPPE--IILP 2675
Query: 679 GAHSPII-FHVKEN-SAGAAIGQI-FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
P+ F E+ G IG + +M IY GN L +N++ AI +D
Sbjct: 2676 RFTEPLYSFSASEDLPIGYEIGTVKADADMPLIYSLVNGNT--LDSNKEL---SFAIDKD 2730
Query: 736 G-TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G T+ Q +D EK +Y++ VIA+ N + A + V I ++D NDN P+FE TY+
Sbjct: 2731 GGTVVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKA 2790
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVKFIGD 851
F+ EN GT + + A DAD N YTL E +MF +D TG + + +
Sbjct: 2791 FLAENLPSGTTVIQ---VTANDADANINGEVSYTLEPESDDIGDMFAIDSQTGWITTLKE 2847
Query: 852 SLDREKKIMYKLSLVARDTG-GLSSEAELI--IMIGDENDNKPEFNQ 895
+ D E K +++ +VA D G L A ++ + + DENDN P+F +
Sbjct: 2848 A-DSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTE 2893
Score = 134 bits (325), Expect = 1e-29
Identities = 167/697 (23%), Positives = 294/697 (42%), Gaps = 58/697 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D + Y I+ FS+D + G + +E D + L + L++
Sbjct: 474 VSAIDVDKDNNGFVTYA-IANTGPVPFSIDPLTGVISTSQEFD----YELMKRWYHLRIW 528
Query: 278 ASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS NP + ++ V I + ++NDN+P FE N SI + G + ++ A D D+
Sbjct: 529 ASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLDEL 588
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD-REAHSSL-RMKV------YAKETNP 388
+ + + + G FSIDP SG + + + ++ +SL +K+ Y + N
Sbjct: 589 QQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNT 648
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
V + + + T EK F + K +E+ +S V++
Sbjct: 649 VTVSITDNGEGAITHCEETGITRQLTEKLIESFRPSLNIK-------EEESISDVHI--- 698
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
N ++P FV S ++ + + + + A D D G NG ++Y + S+
Sbjct: 699 ---INQHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSI---SSGNED 752
Query: 509 SPFKINPNTGTVSVAESPILEGRHALFVEASDQPAN-PSERRYSLAVVTIEVTRGTKGNK 567
F I+ N G + V + E + + + P + L V I +
Sbjct: 753 GCFTIDVNAGDLKVICALDREQKEFYILNITVYDLGYPQTSTWKLLAVNIL----DANDN 808
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVPFAVEERS 626
P P F + Y + N + S+ ++ D N+ ++ L + + F +EE +
Sbjct: 809 P--PLFSQSRYVVTIPENTEVDKSIFKVNAVDFDLDNNGAFKYSLFTFTD--LFQIEEDT 864
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQE---NANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
GV+ V+ L R YD A + + L T+ V + D+ND + P
Sbjct: 865 GVVKVIGPLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDNPPKFV-----P 919
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP 743
++ +K + + G + + + N + T + G++ ++
Sbjct: 920 TVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSESGTFFLD-TSTGSLTLERE 978
Query: 744 LDREKRDVYRMTVIA-EFNK-GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LD EKR Y +TV A + K +S + ++ + +EN N P+F + +ME++K
Sbjct: 979 LDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLDVNENLNRPLFGEMVHTAAVMEDAK 1038
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
IGT + + A D D G + + Y + G G +F VDE TGV++ G LDRE
Sbjct: 1039 IGTSVL---TLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEETGVIQTAG-LLDREVVPH 1094
Query: 861 YKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
Y L++ A+D G L S E+ I + D NDN PE +Q
Sbjct: 1095 YWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELSQ 1131
Score = 122 bits (294), Expect = 8e-26
Identities = 182/771 (23%), Positives = 307/771 (39%), Gaps = 73/771 (9%)
Query: 595 IRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA 654
+RV+ + ++ + + F + ++GVI L NR Y+F+ A A
Sbjct: 376 VRVSVGLSLKNTTFSIQEN-PDSYKFKISAKTGVIVTSQSLDFENRNHYEFDVTANDGEA 434
Query: 655 NLSIVTNATVHVVDVNDER-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
VT V + D ND L + + +V+ ++ ++ I + +
Sbjct: 435 ----VTRVIVDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAI------DVDKDNN 484
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQ 772
G V + IAN V I G I T + D E + Y + + A + +
Sbjct: 485 GFVTYAIANTGPVPFSIDPLT-GVISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECT 543
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
VTI + + NDN PVFE I + +G EI + I A D DE ++ G
Sbjct: 544 VTITMTNVNDNVPVFERVACNASIPRDFAVG-EIIAE--ISALDLDELQQIVYRIES-GN 599
Query: 833 GKEMFDVDENTGVVKF---IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDN 889
+F +D +G++K I + + +Y L + A D ++ + + I D +
Sbjct: 600 DDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNTVTVSITDNGEG 659
Query: 890 KPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP-------- 941
EE R E + I+ + ++Q P F+I
Sbjct: 660 A--ITHCEETGITRQLTEKLIESFRPSLNIKEEESISDVHIINQHSPKFVISTPGSIDIR 717
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ + ++++ NA D DSG NG++ Y +S + +A ++K V
Sbjct: 718 EDFALNRSVLQFNATDNDSGFNGKLVYSISSGNEDGCFTIDVNAGDLK-----------V 766
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
I A + + LNI+ D G + + V + D ND+ P+F ++ Y + E
Sbjct: 767 ICALDREQKEFYILNITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSRYVVTIPENTE 826
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ + KV+A D D N Y + + TDL F+I TGV+ V G LDRET +Y LT
Sbjct: 827 VDKSIFKVNAVDFDLDNNGAFKYSLF-TFTDL-FQIEEDTGVVKVIGPLDRETFRRYDLT 884
Query: 1120 VVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
+ ARD D+NDN PKF + + K PE ++
Sbjct: 885 IEARDQAKPDPQLFSFTDVVVVLEDINDNPPKF--VPTVYKIKVPEDVPPGT----VLLW 938
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY--SLPQRKNQ-QNL-------G 1228
+ + +E I + K + T F+ G + L K Q NL G
Sbjct: 939 VESFDLDLESGGVISYNL-KNSESGTFFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHG 997
Query: 1229 LP-SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--Y 1285
P SLSS+ + + V DV + + ++P+F + + E+ +++L ++
Sbjct: 998 KPRSLSSSCFIEIEVLDVNENL---NRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLG 1054
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ +RYYI +D F +D G + DREV Y + V A+
Sbjct: 1055 RDGVVRYYI---HDGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAK 1102
Score = 119 bits (287), Expect = 5e-25
Identities = 121/448 (27%), Positives = 211/448 (47%), Gaps = 49/448 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTV--IGKVKAVDPDLGQNGMVL 496
L S V + +LD NDN+P F L++ + I ++ A D D+G NGM+
Sbjct: 1213 LSSTATVVIEVLDENDNSPQF-SHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMIT 1271
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF-VEASDQPANPSERRYSLAVV 555
Y L+ + F I+P+TG V+ A + G +++ ++A+DQ NP R S + +
Sbjct: 1272 YSLEDNNE----GRFDIHPDTGVVT-ARGQFVRGNYSILTIQATDQ-GNPP--RMSKSRL 1323
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+E + + D+ F P+ + V + VG IR +N + +D++ G E
Sbjct: 1324 HVEWLPQPEPSS-DVLAFDEPPFNYVVMETDPVTDMVGIIRTE--IPKNLLLFDIIGGDE 1380
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
E F +E+ +G I L+ + Y+ V + + +I T A + VVD+N+ R +
Sbjct: 1381 EQ-DFYIEKNTGSIVKARRLNAGKKSHYNL-TVRVTDGFQ-TITTQAYIQVVDINEHRPM 1437
Query: 676 LLKGAH--------SPI--IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
LK + SP I H+ + A A+ G +F++ SS+ ++++ +Q+
Sbjct: 1438 FLKSLYEVRVPEDTSPWKEILHISAHDADASSG-LFYSIHSSL---NPESLKYFHLDQRS 1493
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
G + ++ LD E + + V+ +K I +V +++ED ND+ P
Sbjct: 1494 ----------GVLVLKEELDYETISTHTLIVMVRDDKIPIK-KNFAKVVVHVEDCNDHIP 1542
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK--EMFDVDENT 843
F YEG I + GTE+ +KA D D G+NA +Y+ G F +D+ T
Sbjct: 1543 SFLDTHYEGIISNLALTGTEVLR---VKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGT 1599
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG 871
G ++ + D+LDR + Y L++ A D G
Sbjct: 1600 GSIR-VSDALDRLPQEHYHLTVKATDQG 1626
Score = 118 bits (285), Expect = 9e-25
Identities = 233/971 (23%), Positives = 382/971 (39%), Gaps = 117/971 (12%)
Query: 215 PEPIHAIDQDLGVGA-TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
P H + +G+ + + D F + + G + + LD + N +
Sbjct: 370 PPKTHVVRVSVGLSLKNTTFSIQENPDSYKFKISAKTGVIVTSQSLDFE-----NRNHYE 424
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
V A+ A RV +++ D NDN P F + Y S+ EN+ G SVL V A D
Sbjct: 425 FDVTAND-----GEAVTRVIVDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDV 479
Query: 334 DQGENGEFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSS-LRMKVYAKET-NPSV 390
D+ NG TY + + FSIDP +G ++ + D E ++++A ++ NP
Sbjct: 480 DKDNNGFVTYAIANTGPVPFSIDPLTGVISTSQE--FDYELMKRWYHLRIWASDSGNPF- 536
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
R+++ TN + VF ++V N + + + E++ L
Sbjct: 537 -------NRVSECTVTITMTN--VNDNVPVF-ERVAC---NASIPRDFAVGEIIAEISAL 583
Query: 451 DAND-NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITS 509
D ++ V+ + + + S V +I KA+ + LY L+ T+
Sbjct: 584 DLDELQQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITAT---DG 640
Query: 510 PFKINPNTGTVSVAESPILEGRHALFVEASDQPANP--SERRYSLAVVTIEVTRGTKGNK 567
+ +PNT TVS+ ++ H + Q R SL + E
Sbjct: 641 TYIADPNTVTVSITDNGEGAITHCEETGITRQLTEKLIESFRPSLNIKEEESISDVHIIN 700
Query: 568 PDIPDFM-GAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEE 624
P F+ P + + + SV Q ND+ + Y + G E+G F ++
Sbjct: 701 QHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSISSGNEDGC-FTIDV 759
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
+G + V+ L R + Y S V+++D ND + + S
Sbjct: 760 NAGDLKVICALDREQKEFYILNITVYDLGYPQTSTWKLLAVNILDANDNPPLF---SQSR 816
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GTIFTQK 742
+ + EN+ IF N + G ++ + TD I ED G +
Sbjct: 817 YVVTIPENTE--VDKSIFKVNAVDFDLDNNGAFKYSLFT---FTDLFQIEEDTGVVKVIG 871
Query: 743 PLDREKRDVYRMTVIAEFN-KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
PLDRE Y +T+ A K V + +ED NDNPP F Y+
Sbjct: 872 PLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDNPPKFVPTVYK-------- 923
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD-ENTGVVKFIGDSLDREKKIM 860
IK+ D GT L++ E FD+D E+ GV+ + +L +
Sbjct: 924 ----IKVPE-----DVPPGTVLLWV--------ESFDLDLESGGVISY---NLKNSESGT 963
Query: 861 YKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIE 920
+ L TG L+ E EL + K +F + + H + + ++ F IE
Sbjct: 964 FFLDT---STGSLTLEREL-------DFEKRQFYNL--TVRAVDHGKPRSLSSSCFIEIE 1011
Query: 921 VKPKNKFALDVDQLGPLF---LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
V N+ L+ G + + E+ IGT+++ L A+D D G +G +RY YI
Sbjct: 1012 VLDVNE-NLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRY------YIH 1064
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFV 1035
L V F ++E G + A L E + L + A D G + V++
Sbjct: 1065 ----DGSGLGV---FTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYI 1117
Query: 1036 K--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
+ D+ND+ P + Y +V+E + + KV ATD D L + I S + F
Sbjct: 1118 EVWDINDNPPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQILDSQR-IYF 1176
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
I TGV+S LDRE + ++I+ V+ D G D NDNSP+F
Sbjct: 1177 TIDSKTGVISTLSSLDREQKAEHIIEVMVSDKG-EPPLSSTATVVIEVLDENDNSPQF-- 1233
Query: 1154 FDELLEWKHPE 1164
+L + K PE
Sbjct: 1234 SHKLFQIKLPE 1244
Score = 113 bits (273), Expect = 3e-23
Identities = 122/442 (27%), Positives = 199/442 (45%), Gaps = 28/442 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D QL SF +V V L D NDN P FVP+ +Y+ + + GTV+ V++ D DL G++
Sbjct: 894 DPQLFSFTDVVVVLEDINDNPPKFVPT-VYKIKVPEDVPPGTVLLWVESFDLDLESGGVI 952
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y+L+ + + T F ++ +TG++++ E R F + + + + R +
Sbjct: 953 SYNLKNSESGT----FFLDTSTGSLTLERELDFEKRQ--FYNLTVRAVDHGKPRSLSSSC 1006
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
IE+ + P F + V + IGTSV + ND V Y + G
Sbjct: 1007 FIEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDG 1066
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV--TNATVHVVDVND 671
GV F V+E +GVI L R P Y + V ++ + +V T + V D+ND
Sbjct: 1067 SGLGV-FTVDEETGVIQTAGLLDREVVPHY-WLTVYAKDLGTIPLVSWTEVYIEVWDIND 1124
Query: 672 ERGVLLKGAHSPIIF-HVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
L P+ F V+EN ++ ++ T+M + G + F I + Q +
Sbjct: 1125 NPPEL----SQPVYFGSVQENLPKDKSVLKVSATDMDK---SSEGKLAFQILDSQRIYFT 1177
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I ++ G I T LDRE++ + + V+ +KG + V I + DENDN P F H
Sbjct: 1178 ID-SKTGVISTLSSLDREQKAEHIIEVMVS-DKGEPPLSSTATVVIEVLDENDNSPQFSH 1235
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
++ + E + ++ A D D G N + Y+L + FD+ +TGVV
Sbjct: 1236 KLFQIKLPERQSTAEPQDIYRMV-ARDDDVGPNGMITYSLEDNNEGRFDIHPDTGVVTAR 1294
Query: 850 GDSLDREKKIMYKLSLVARDTG 871
G + I L++ A D G
Sbjct: 1295 GQFVRGNYSI---LTIQATDQG 1313
Score = 105 bits (253), Expect = 7e-21
Identities = 108/458 (23%), Positives = 192/458 (41%), Gaps = 25/458 (5%)
Query: 446 EVTLL--DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+VTL+ D NDN P F S+ YE ++ N + T I + A DPD G N V Y LQ
Sbjct: 3083 DVTLMVQDMNDNPPQFSTSH-YEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGAD 3141
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F ++ +G + + S E + ++ +S A++T+ V +
Sbjct: 3142 S----GFFSLDEISGVLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILS 3197
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFA 621
P F+ + Y + + +G+ V + DA E V Y ++ G E+G F
Sbjct: 3198 DYQ----PLFLSSEYSVQIAESSQVGSEVISVSALTKDATENEPVRYSIISGNEDG-RFM 3252
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ +G+++V L Y + LS + +++ DVND V + ++
Sbjct: 3253 INPVTGLLSVKAALDFERCREYYLSVEGARGKPLLSDIAMVIINITDVNDNPPVFNRSSY 3312
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
S +I ++ S G Q+ ++ G + + I + G I +
Sbjct: 3313 STVI--PEDISPGEMALQVRAIDLD---GPPNNFIIYSIVSGDPKQQFSIDPRTGFITLR 3367
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LDRE+ Y +TV A ++G + QVT+ + D NDNPP+F + + E
Sbjct: 3368 SMLDREEITHYSLTVQAA-DEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEA 3426
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
+G+ I + ++ D + + + G F +D+ G + + L R K +
Sbjct: 3427 VGSGI-LQLLVTDRDTPQNGPPFSFHIVSGNEDRSFHIDQ--GGLLSVSSQLRRRGKPQH 3483
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
L + D+G LSS + I I +++ P N +E
Sbjct: 3484 LLKIQVTDSGHPPLSSICVVKINITEQSRYPPTVNPLE 3521
Score = 99.5 bits (237), Expect = 6e-19
Identities = 109/462 (23%), Positives = 190/462 (41%), Gaps = 40/462 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ ++D N++ P+F+ S LYE + + I + A D D + Y + + N
Sbjct: 1426 IQVVDINEHRPMFLKS-LYEVRVPEDTSPWKEILHISAHDADASSG--LFYSIHSSLNPE 1482
Query: 507 ITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F ++ +G + + E E H L V D P ++ ++ VV +E
Sbjct: 1483 SLKYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKI-PIKKNFAKVVVHVEDCND-- 1539
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAV 622
IP F+ YE + + GT V +++ D D+ Y G F +
Sbjct: 1540 ----HIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYSFHSGGNVDGAFKI 1595
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAH 681
++ +G I V D L R + Y A + S + T+ +
Sbjct: 1596 DQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTI----------TIKLSEF 1645
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFT 740
+P F KE + + + S+ +V + I N+ D I G +
Sbjct: 1646 TPPRFSSKEYITEISEAMPPGSPVLSVSARCPSSVLYRI-NEGDPNGTFHININSGLLSV 1704
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
+ LD E+ Y + + A G+ S A ++ +Y+ D NDN PVF Y G I E++
Sbjct: 1705 KNALDFEQHSSYHLQISATNTAGISSDAVVF---VYVIDANDNAPVFHQDVYYGQISESA 1761
Query: 801 KIGTEIKMDN----IIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDR 855
+ + + +N +IKA+DAD+ TNAL +Y + E+F +D + G + + +D
Sbjct: 1762 PVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMGTIS-LKSLIDF 1820
Query: 856 EKKIMYKLSLVARDTG----GLSSEAELIIMIGDENDNKPEF 893
E + S+ D+G S ++II + D ND P+F
Sbjct: 1821 EATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKF 1862
Score = 97.1 bits (231), Expect = 3e-18
Identities = 113/468 (24%), Positives = 190/468 (40%), Gaps = 55/468 (11%)
Query: 932 DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY 991
+QL + EN G I+K++A D D G NGQ+ + + +AD
Sbjct: 2997 EQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGP--------NADK------ 3042
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F ++ + G + L E E+ L + A DGG + V + V+D+ND+ P F +
Sbjct: 3043 FHLDPKTGELFTLAVLDREREKEYDLVVKATDGGGRSCQADVTLMVQDMNDNPPQFSTSH 3102
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y V + R + + A D D G N+ + Y +Q +D+ F + ++GVL + L
Sbjct: 3103 YEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGADSGF-FSLDEISGVLRLERSLA 3161
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
ET+ Y + V A D G ++D P F + + ++ E+ ++
Sbjct: 3162 DETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSVQ--IAESSQVG 3219
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQN 1226
+ V+ + EN P+ ++ + I GL+ +R +
Sbjct: 3220 S----EVISVSALTKDATENEPVRYSIISGNEDGRFMINPVTGLLSVKAALDFERCREYY 3275
Query: 1227 L------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
L G P LS A++++ + DV D + PVF Y I E++ +P E+
Sbjct: 3276 LSVEGARGKPLLSDIAMVIINITDVND-----NPPVFNRSSYSTVIPEDI-SPGEMALQV 3329
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ + I + D ++ F IDPR G + L DRE Y + V+
Sbjct: 3330 RAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHYSLTVQ------ 3383
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
A D + V+V V + DVNDN P F+ N L+
Sbjct: 3384 -----------AADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLI 3420
Score = 95.1 bits (226), Expect = 1e-17
Identities = 96/310 (30%), Positives = 145/310 (46%), Gaps = 22/310 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTI 140
V VYI+DVNDNVP L+ P + + + T G+ F L G + +I ++ +
Sbjct: 2046 VKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDDFGL 2105
Query: 141 FK-DIRAFD--RDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
F+ D+ D +P S Y + V +DDG +L + + ++ +
Sbjct: 2106 FRIDLYLGDVSLQRPLDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQ-----NRSHPI 2160
Query: 197 FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
FQ M ++ + I I + G L Y L N +LF++D G L +
Sbjct: 2161 FQS--MYYPLKLPENITPFTTILHVQARNPEGYRLIYNLEEDNASRLFNIDFKTGVLSVT 2218
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV 316
LD ++E +L V+A+ + A+A+VEI++ D+NDN P F+ Y +
Sbjct: 2219 DFLDFESE-----TKHILTVRATDSVSGT-FAEAKVEIDVEDINDNAPVFQNLSYVADVF 2272
Query: 317 ENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHS 375
E LP G SVLQV A D+D +N E TYQL D + F IDP SG L VLD E+
Sbjct: 2273 EGLPIGTSVLQVSAVDRDADKNAEATYQLIDKESHFFEIDPLSGVLVTTQ--VLDYESTQ 2330
Query: 376 SLRMKVYAKE 385
+KV A +
Sbjct: 2331 QFTLKVKATD 2340
Score = 88.6 bits (210), Expect = 1e-15
Identities = 92/334 (27%), Positives = 147/334 (44%), Gaps = 50/334 (14%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPRG 137
+ +V + + D NDNVP F + Y +++ G + A G + + TV
Sbjct: 2553 FCTVKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEA 2612
Query: 138 LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
+ +DI + P T V S+V LE+ + KV D G +
Sbjct: 2613 DEVTEDIIEVN---PFTGVVSVKESLVG--------LENK----IFNFKVKARDGGFPFY 2657
Query: 198 QLVIMASGKRIHKEILFP---EPIHAID--QDLGVG-----------ATLRYELISGN-- 239
+ K + EI+ P EP+++ +DL +G L Y L++GN
Sbjct: 2658 NSSVPVQVKVVPPEIILPRFTEPLYSFSASEDLPIGYEIGTVKADADMPLIYSLVNGNTL 2717
Query: 240 --DRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ-ARVEIE 295
+++L F++D G++ L+ +D + + + + V A +N A V IE
Sbjct: 2718 DSNKELSFAIDKDGGTVVLQNNIDHE-----KTKMYKIDVIAQGNHNGTNVASLVSVHIE 2772
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGA 351
+ D+NDN P FE D Y + ENLP+G +V+QV A D D NGE +Y L DD
Sbjct: 2773 VQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYTLEPESDDIGDM 2832
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F+ID ++GW+T + D E R V A +
Sbjct: 2833 FAIDSQTGWITTLKEA--DSETKQLHRFFVVATD 2864
Score = 87.8 bits (208), Expect = 2e-15
Identities = 128/539 (23%), Positives = 226/539 (41%), Gaps = 56/539 (10%)
Query: 830 FGEGKEMFDVDENTGVVKFIGD-SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEND 888
F E F E+ + IG D + ++Y SLV +T L S EL I +
Sbjct: 2677 FTEPLYSFSASEDLPIGYEIGTVKADADMPLIY--SLVNGNT--LDSNKELSFAIDKDGG 2732
Query: 889 NKPEFNQIEENS----KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF------ 938
N I+ K+ + + NGT +++ V + + DV+ P+F
Sbjct: 2733 TVVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQ---DVNDNKPMFEADTYK 2789
Query: 939 -LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ EN+P GTT+I++ A D D+ +NG++ Y L ++ ++ F I+ +
Sbjct: 2790 AFLAENLPSGTTVIQVTANDADANINGEVSY-----------TLEPESDDIGDMFAIDSQ 2838
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNL---NDNISVRVFVKDVNDHFPVFKKTWYNF 1052
G + + E++ R + A D G+ + ++ V V + D ND+ P F + Y
Sbjct: 2839 TGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTEELYQG 2898
Query: 1053 NVEEAQYTRRVLGKVDATDADF-GQNANLTYFIQPSDTDLPFEISPLTGVLSV--NGELD 1109
++ E + + D D +N + +I D F ++ + +V LD
Sbjct: 2899 SILENSRPGENIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLD 2958
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RE +DKY L ++A D D+NDNSP F E L+ + EA +
Sbjct: 2959 REDKDKYTLKIIATDG----RFQTSANVEVHVLDLNDNSP----FCEQLQ--YTEAVMEN 3008
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
+ + + ++ I I N + T+ A+ L ++ R+ ++ L
Sbjct: 3009 SSSGKVILKISASDPDIGTNGQVSFTLHGPNADKFHLDPKTGELFTLAVLDREREKEYDL 3068
Query: 1230 PSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEEN--VNAPVELVSLNLTEHY 1285
++ ADV V +M+D P F + +YE+ + +N + P+ ++ +
Sbjct: 3069 VVKATDGGGRSCQADVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTG 3128
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
N ++R Y L D+ F +D +G L L RS E K TYE+ V+A + R L
Sbjct: 3129 INSEVR-YSLQGADSGF---FSLDEISGVLRLERSLADETKSTYEMKVKATDRGLPRHL 3183
Score = 80.2 bits (189), Expect = 4e-13
Identities = 58/193 (30%), Positives = 97/193 (50%), Gaps = 20/193 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +GT +I+L A+D D G G + Y +++ AD F INE G
Sbjct: 2475 LAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINKL--------AD-----EKFAINE-DG 2520
Query: 1000 HVIVARSL----PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ ++ L P + + I A DGG +V++ + D ND+ P FK + Y+ +++
Sbjct: 2521 QIVTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIILTDENDNVPQFKASEYDISIQ 2580
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSD--TDLPFEISPLTGVLSVNGELDRETE 1113
+ ++ A DAD G+NA++TY ++ +D T+ E++P TGV+SV L
Sbjct: 2581 STVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSVKESLVGLEN 2640
Query: 1114 DKYILTVVARDNG 1126
+ V ARD G
Sbjct: 2641 KIFNFKVKARDGG 2653
Score = 79.4 bits (187), Expect = 7e-13
Identities = 186/806 (23%), Positives = 318/806 (39%), Gaps = 90/806 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI-GK------VKAVDPDLGQNGMVLY 497
V V ++DANDN PVF ++Y + +A V +++ G+ +KA D D N +++Y
Sbjct: 1734 VFVYVIDANDNAPVF-HQDVYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVY 1792
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ + + FKI+P+ GT+S+ E F S Q + E S +
Sbjct: 1793 QILEPAAHEV---FKIDPSMGTISLKSLIDFEATPEFFF--SVQVWDSGEPSLSASKPCK 1847
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+ R N P F+ YE + V V Q+ +DA + V+Y +L +
Sbjct: 1848 VIIRVLDFNDCP-PKFVLPVYEIALTWPVFQDMKVIQVTAHDA--DSAVTYMILENSNKN 1904
Query: 618 VPFAVEERSGVITVVD--DLSRYNR-PMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F +++ +GVI+V D +L +N + F+ + +TNAT + D
Sbjct: 1905 A-FKIDQSTGVISVNDSSELQSHNELKITAFDGLYKDTTVVKLNITNATKSSLKFEDR-- 1961
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
AH + V ENS I + + Y N ++F + N I
Sbjct: 1962 -----AH---VATVLENSTSVKILVVLRA--TGTYLNEP--LQFTVLNPHG--KFAVIPS 2007
Query: 735 DGTIFTQ-KPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + T P DRE++DVY + V + +F + V +YI+D NDN P +
Sbjct: 2008 SGVLHTTGVPFDREEQDVYDVAVEVRDFRSP--PRVDVTHVKVYIDDVNDNVPEILNLPK 2065
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I + ++ G + + ATD D G N +++L + +F +D G V +
Sbjct: 2066 TLLISDETEPGDVLFQ---VLATDNDFGENGSIIFSL-EDDFGLFRIDLYLGDVS-LQRP 2120
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
LD E Y L+++ D G S A I I +N + P F + K+ N
Sbjct: 2121 LDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQNRSHPIFQSMYYPLKL------PENI 2174
Query: 913 TAGFTIIEVKPKNK------FALDVDQLGPLFLIPENIPIGTTIIKL-NALDLDSGLNGQ 965
T TI+ V+ +N + L+ D LF NI T ++ + + LD +S
Sbjct: 2175 TPFTTILHVQARNPEGYRLIYNLEEDNASRLF----NIDFKTGVLSVTDFLDFESETKHI 2230
Query: 966 IRYEFNSEV--YIPPSKLSADALEVKRYFVINERHGHVI-VARSLPPESEFRLNISALDG 1022
+ V +K+ D ++ + + +V V LP + L +SA+D
Sbjct: 2231 LTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQNLSYVADVFEGLPIGTSV-LQVSAVD- 2288
Query: 1023 GNLNDNISVRVFVKDVNDHF---PVFKKTWYNFNVEEAQYTRRVLGKVDATDADF----G 1075
+ + N + D HF V + + T++ KV ATD G
Sbjct: 2289 RDADKNAEATYQLIDKESHFFEIDPLSGVLVTTQVLDYESTQQFTLKVKATDKGVPPLSG 2348
Query: 1076 Q----------NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ N N F +PS E++ ++ D +++D +++ +
Sbjct: 2349 EAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPDSKDDLQYKILSGNE 2408
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFY-----AFDELLEWKHPEADELSNHN-FESVMMI 1179
G N FY D + + P +++N N +
Sbjct: 2409 GRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGVFQKTAPVNIDMTNGNKYSPYFTQ 2468
Query: 1180 PVYKATIEENAPIGTTVAKVFANDTD 1205
+Y+A + ENA +GT V ++ A D D
Sbjct: 2469 NIYEADLAENAEVGTRVIRLAAIDPD 2494
Score = 79.0 bits (186), Expect = 9e-13
Identities = 108/459 (23%), Positives = 193/459 (42%), Gaps = 41/459 (8%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
N ++P+F S Y + N T I V+A +P+ ++Y+L+ + + F
Sbjct: 2155 NRSHPIF-QSMYYPLKLPENITPFTTILHVQARNPE---GYRLIYNLEEDNASRL---FN 2207
Query: 513 INPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
I+ TG +SV + E +H L V A+D + ++ A V I+V + +
Sbjct: 2208 IDFKTGVLSVTDFLDFESETKHILTVRATDSVSGT----FAEAKVEIDV----EDINDNA 2259
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGV 628
P F Y V + IGTSV Q+ DA + + +Y L+ +E F ++ SGV
Sbjct: 2260 PVFQNLSYVADVFEGLPIGTSVLQVSAVDRDADKNAEATYQLID--KESHFFEIDPLSGV 2317
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ L + + + A + LS + V+V+DVND + ++ +
Sbjct: 2318 LVTTQVLDYESTQQFTLKVKATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDE 2377
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
+ A G I + + + ++++ I + + G I R
Sbjct: 2378 M------ATCGNIV-IKVQASDPDSKDDLQYKILSGNEGRYFAINESSGLISFSNVCKRN 2430
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
Y +TV + GV V I + + N P F YE + EN+++GT +
Sbjct: 2431 LDPFYNLTVAV--SDGVFQKTA--PVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVI 2486
Query: 808 MDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGDSLDREK--KIMYKLS 864
+ A D D+G YT+ + E F ++E+ +V LDRE + + +
Sbjct: 2487 R---LAAIDPDDGPYGSVDYTIINKLADEKFAINEDGQIVT--SQPLDRENPSQRVIAIK 2541
Query: 865 LVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
++A+D GG + I++ DENDN P+F E + ++
Sbjct: 2542 IMAKDGGGRVGFCTVKIILTDENDNVPQFKASEYDISIQ 2580
Score = 78.2 bits (184), Expect = 2e-12
Identities = 116/510 (22%), Positives = 214/510 (41%), Gaps = 56/510 (10%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSN-AKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+V+V + D NDN P + NL + + S+ + G V+ +V A D D G+NG +++ L+
Sbjct: 2045 HVKVYIDDVNDNVPEIL--NLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDD 2102
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F+I+ G VS+ E ++ L V SD PS ++ + I+V
Sbjct: 2103 FGL-----FRIDLYLGDVSLQRPLDFESMNKYVLTVLVSDD-GQPS--LSAIGTIYIQVQ 2154
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP- 619
+ P F Y + N+ T++ ++ +N Y L++ EE
Sbjct: 2155 NRSH------PIFQSMYYPLKLPENITPFTTILHVQA-----RNPEGYRLIYNLEEDNAS 2203
Query: 620 --FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F ++ ++GV++V D L + + A + + V D+ND V
Sbjct: 2204 RLFNIDFKTGVLSVTDFLDFESETKHILTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQ 2263
Query: 678 KGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
++ +F G IG + + + + + +++ +I G
Sbjct: 2264 NLSYVADVFE------GLPIGTSVLQVSAVDRDADKNAEATYQLIDKESHFFEID-PLSG 2316
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ T + LD E + + V A +KGV +G + + + D NDNPP F +Y +
Sbjct: 2317 VLVTTQVLDYESTQQFTLKVKAT-DKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASL 2375
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E + G + ++A+D D + + EG+ F ++E++G++ F + R
Sbjct: 2376 DEMATCGNIVIK---VQASDPDSKDDLQYKILSGNEGR-YFAINESSGLISF-SNVCKRN 2430
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ------IEENSKV--RIHRET 908
Y L++ D G A + I + + N P F Q + EN++V R+ R
Sbjct: 2431 LDPFYNLTVAVSD-GVFQKTAPVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLA 2489
Query: 909 KLN------GTAGFTIIEVKPKNKFALDVD 932
++ G+ +TII KFA++ D
Sbjct: 2490 AIDPDDGPYGSVDYTIINKLADEKFAINED 2519
Score = 77.4 bits (182), Expect = 3e-12
Identities = 102/474 (21%), Positives = 197/474 (41%), Gaps = 52/474 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+P +++K++A D+D G++ ++ D+ + YF I+ + G
Sbjct: 1138 VQENLPKDKSVLKVSATDMDKSSEGKLAFQI------------LDSQRI--YFTIDSKTG 1183
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ SL E +E + + D G L+ +V + V D ND+ P F + +
Sbjct: 1184 VISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLP 1243
Query: 1056 EAQYTR--RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E Q T + + ++ A D D G N +TY ++ + + F+I P TGV++ G+ R
Sbjct: 1244 ERQSTAEPQDIYRMVARDDDVGPNGMITYSLE-DNNEGRFDIHPDTGVVTARGQFVRGNY 1302
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE-LLEWKHPEADELSNHN 1172
ILT+ A D G +S AFDE + E D +++
Sbjct: 1303 S--ILTIQATDQGNPPRMSKSRLHVEWLPQPEPSS-DVLAFDEPPFNYVVMETDPVTD-- 1357
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
M+ + + I +N + + D N ++ + + L
Sbjct: 1358 -----MVGIIRTEIPKNLLLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVR 1412
Query: 1233 SSTAILMVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMR 1291
+ +T V++++ +P+F+ YE+ + E+ + E++ ++ + + +
Sbjct: 1413 VTDGFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLF 1472
Query: 1292 YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPV 1351
Y I + + + + F +D R+G L L D E T+ +IV K +P
Sbjct: 1473 YSIHSSLNPESLKYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDK----IP------ 1522
Query: 1352 AEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
+ K KVVV ++D ND+ P F + + + I A G +V+++K
Sbjct: 1523 -------IKKNFAKVVVHVEDCNDHIPSFLDTHYEGI--ISNLALTGTEVLRVK 1567
Score = 75.8 bits (178), Expect = 9e-12
Identities = 107/418 (25%), Positives = 172/418 (41%), Gaps = 53/418 (12%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F IN G + V +L E S + L ISA + ++ + V V+V D ND+ PVF +
Sbjct: 1693 FHININSGLLSVKNALDFEQHSSYHLQISATNTAGISSDAVVFVYVIDANDNAPVFHQDV 1752
Query: 1050 YNFNVEE-AQYTRRVLGK------VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
Y + E A V G+ + A+DAD NA L Y I F+I P G +
Sbjct: 1753 YYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMGTI 1812
Query: 1103 SVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLE 1159
S+ +D E ++ +V D+G D ND PKF ++ L
Sbjct: 1813 SLKSLIDFEATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALT 1872
Query: 1160 W---KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
W + + +++ H+ +S + + + + + I + + ND+ + + N L +
Sbjct: 1873 WPVFQDMKVIQVTAHDADSAVTYMILENSNKNAFKIDQSTGVISVNDSSELQSHNELKIT 1932
Query: 1217 SLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
+ GL ++ L +T A + S K F R + + EN + L
Sbjct: 1933 AFD--------GLYKDTTVVKLNITNA-----TKSSLK--FEDRAHVATVLENSTSVKIL 1977
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRA 1335
V L T Y N +++ +LN + F + P +G L+ P DRE +D Y+V V
Sbjct: 1978 VVLRATGTYLNEPLQFTVLNPHG-----KFAVIPSSGVLHTTGVPFDREEQDVYDVAV-- 2030
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
E+ P DV V V I DVNDN P+ N + L+ + T
Sbjct: 2031 -------EVRDFRSPPRVDV--------THVKVYIDDVNDNVPEILNLPKTLLISDET 2073
Score = 70.5 bits (165), Expect = 3e-10
Identities = 56/193 (29%), Positives = 91/193 (47%), Gaps = 15/193 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L ++++ + R F++DS G + LD + Q +++V
Sbjct: 1151 VSATDMDKSSEGKLAFQILD-SQRIYFTIDSKTGVISTLSSLDRE-----QKAEHIIEVM 1204
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE--NLPNGFSVLQVMATDKDQ 335
S P ++ A V IE+LD NDN P+F + I + E + + +++A D D
Sbjct: 1205 VSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDV 1264
Query: 336 GENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
G NG TY L+D +G F I P +G +T R Q V R +S L ++ + NP
Sbjct: 1265 GPNGMITYSLEDNNEGRFDIHPDTGVVTARGQFV--RGNYSILTIQA-TDQGNPP---RM 1318
Query: 395 ADSQRIAKWRRQP 407
+ S+ +W QP
Sbjct: 1319 SKSRLHVEWLPQP 1331
Score = 69.7 bits (163), Expect = 6e-10
Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 17/174 (9%)
Query: 216 EPIHAIDQDLGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
E +H D + L Y + S K F LD +G L L++ELD + + +T
Sbjct: 1456 EILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGVLVLKEELDYET---ISTHTL 1512
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVMAT 331
++ V+ ++ P+K A+V + + D ND++P F +D + I+ NL G VL+V A
Sbjct: 1513 IVMVRDDKI--PIKKNFAKVVVHVEDCNDHIPSF-LDTHYEGIISNLALTGTEVLRVKAL 1569
Query: 332 DKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDR--EAHSSLRMK 380
DKD G N + Y + GAF ID +G ++R LDR + H L +K
Sbjct: 1570 DKDTGSNADIVYSFHSGGNVDGAFKIDQGTG--SIRVSDALDRLPQEHYHLTVK 1621
Score = 67.7 bits (158), Expect = 2e-09
Identities = 67/240 (27%), Positives = 109/240 (45%), Gaps = 25/240 (10%)
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTII 951
N+ + H + T GF I + + +D+++ P+FL +PE+ I+
Sbjct: 1400 NAGKKSHYNLTVRVTDGFQTITTQAYIQ-VVDINEHRPMFLKSLYEVRVPEDTSPWKEIL 1458
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE- 1010
++A D D+ + Y S L+ ++L +YF +++R G +++ L E
Sbjct: 1459 HISAHDADAS---------SGLFYSIHSSLNPESL---KYFHLDQRSGVLVLKEELDYET 1506
Query: 1011 -SEFRLNISALDGG-NLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
S L + D + N + V V V+D NDH P F T Y + T + +V
Sbjct: 1507 ISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRV 1566
Query: 1068 DATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
A D D G NA++ Y F + D F+I TG + V+ LDR ++ Y LTV A D G
Sbjct: 1567 KALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQG 1626
Score = 66.5 bits (155), Expect = 5e-09
Identities = 57/193 (29%), Positives = 95/193 (49%), Gaps = 19/193 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPE+I G +++ A+DLD N I Y S +S D K+ F I+ R
Sbjct: 3315 VIPEDISPGEMALQVRAIDLDGPPNNFIIY----------SIVSGDP---KQQFSIDPRT 3361
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + L E + + L + A D G+ L+ + V V V DVND+ P+F K ++ V
Sbjct: 3362 GFITLRSMLDREEITHYSLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIV 3421
Query: 1055 EEAQYTRRVLGKVDATDADFGQNA-NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+E + + ++ TD D QN ++ I + D F I G+LSV+ +L R +
Sbjct: 3422 QEGEAVGSGILQLLVTDRDTPQNGPPFSFHIVSGNEDRSFHIDQ-GGLLSVSSQLRRRGK 3480
Query: 1114 DKYILTVVARDNG 1126
+++L + D+G
Sbjct: 3481 PQHLLKIQVTDSG 3493
Score = 65.7 bits (153), Expect = 9e-09
Identities = 78/280 (27%), Positives = 117/280 (41%), Gaps = 52/280 (18%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYIPPSKLSADALEVKRYFVINERH 998
+PE++P GT ++ + + DLD G I Y NSE F ++
Sbjct: 926 VPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSE---------------SGTFFLDTST 970
Query: 999 GHVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFVKDVNDHF--PVFKKTWYN 1051
G + + R L E + L + A+D G +L+ + + + V DVN++ P+F + +
Sbjct: 971 GSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLDVNENLNRPLFGEMVHT 1030
Query: 1052 FNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
V E+A+ VL + A D D G++ + Y+I F + TGV+ G LDR
Sbjct: 1031 AAVMEDAKIGTSVL-TLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEETGVIQTAGLLDR 1089
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E Y LTV A+D G D+NDN P ELS
Sbjct: 1090 EVVPHYWLTVYAKDLG-TIPLVSWTEVYIEVWDINDNPP-----------------ELSQ 1131
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
PVY +++EN P +V KV A D D G
Sbjct: 1132 ---------PVYFGSVQENLPKDKSVLKVSATDMDKSSEG 1162
Score = 65.3 bits (152), Expect = 1e-08
Identities = 54/202 (26%), Positives = 98/202 (48%), Gaps = 13/202 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D + Y ++SG+ ++ FS+D G + L LD + + + L VQ
Sbjct: 3329 VRAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFITLRSMLDRE-----EITHYSLTVQ 3383
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +P ++ +V + + D+NDN P F +++ + E G +LQ++ TD+D +
Sbjct: 3384 AADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTDRDTPQ 3443
Query: 338 NG-EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
NG F++ + + +F ID + G L+V +Q L R +K+ ++ +P +
Sbjct: 3444 NGPPFSFHIVSGNEDRSFHID-QGGLLSVSSQ--LRRRGKPQHLLKIQVTDSGHPPLSSI 3500
Query: 394 FADSQRIAKWRRQPLETNAPLE 415
I + R P N PLE
Sbjct: 3501 CVVKINITEQSRYPPTVN-PLE 3521
Score = 64.1 bits (149), Expect = 3e-08
Identities = 79/314 (25%), Positives = 131/314 (41%), Gaps = 38/314 (12%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPLTVPRG 137
+ V V++ED ND++P FLDT Y + L TG + L G + I + G
Sbjct: 1527 FAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYSFHSG 1586
Query: 138 LTIFKDIRAFDRDKPNTPNSDV-------HYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
+ + D+ + SD HY + D F S+ PV + K+ ++
Sbjct: 1587 GNVDGAFK-IDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIKLSEF 1645
Query: 191 DAGDKEFQLVIMASGKRIHKEI--LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
F S K EI P + +++ Y + G+ F ++
Sbjct: 1646 TP--PRF------SSKEYITEISEAMPPGSPVLSVSARCPSSVLYRINEGDPNGTFHINI 1697
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
+G L ++ LD + Q +++ LQ+ A+ N ++ A V + ++D NDN P F
Sbjct: 1698 NSGLLSVKNALDFE-----QHSSYHLQISAT--NTAGISSDAVVFVYVIDANDNAPVFHQ 1750
Query: 309 DFYNISIVENLPNGFSV-------LQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSG 359
D Y I E+ P V L + A+D D+ N YQ+ +P F IDP G
Sbjct: 1751 DVYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMG 1810
Query: 360 WLTVRNQTVLDREA 373
T+ ++++D EA
Sbjct: 1811 --TISLKSLIDFEA 1822
Score = 63.7 bits (148), Expect = 4e-08
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 8/167 (4%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT-----FVLQVQASQLNNPL 285
++Y+++SG+D LF + + F + + ++ N + L V+A++
Sbjct: 63 IKYKIVSGDDDGLFQTEKEDVGDFSFLRIITRSSNSAVLNREVRDIYTLTVEATESTFDN 122
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A+ +V I++LD ND P F Y++ I E+ P S+++V ATD D G N EF Y
Sbjct: 123 R-ARTKVLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSF 181
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
F++DP +G +T+ + LD + V A++ + G
Sbjct: 182 TTRSHPFAVDPFTGTVTLVKR--LDTSQRDRYDLTVLAEDRKKKISG 226
Score = 63.7 bits (148), Expect = 4e-08
Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
L+RE RD+Y +TV E + +V I + D ND P+F A+Y I E++ I
Sbjct: 101 LNREVRDIYTLTV--EATESTFDNRARTKVLIQVLDTNDLKPLFYPASYHVVIKEDTPIK 158
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+ + + ATDAD G+NA F Y+ F F VD TG V + LD ++ Y L
Sbjct: 159 SSLVR---VSATDADIGSNAEFYYS-FTTRSHPFAVDPFTGTVTLV-KRLDTSQRDRYDL 213
Query: 864 SLVARD 869
+++A D
Sbjct: 214 TVLAED 219
Score = 63.7 bits (148), Expect = 4e-08
Identities = 39/148 (26%), Positives = 74/148 (50%), Gaps = 6/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D A Y+LI + F +D ++G L + LD ++ F L+V+
Sbjct: 2284 VSAVDRDADKNAEATYQLID-KESHFFEIDPLSGVLVTTQVLDYESTQQ-----FTLKVK 2337
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P + +A + + ++D+NDN P+F Y S+ E G V++V A+D D +
Sbjct: 2338 ATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPDSKD 2397
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
+ ++ + F+I+ SG ++ N
Sbjct: 2398 DLQYKILSGNEGRYFAINESSGLISFSN 2425
Score = 62.5 bits (145), Expect = 9e-08
Identities = 41/153 (26%), Positives = 78/153 (50%), Gaps = 10/153 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D G ++ Y +I+ + F+++ +G + + LD + N +++ A
Sbjct: 2490 AIDPDDGPYGSVDYTIINKLADEKFAINE-DGQIVTSQPLDRE---NPSQRVIAIKIMAK 2545
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ V+I L D NDN+P+F+ Y+ISI + G V+Q+MA D D+G+N
Sbjct: 2546 DGGG--RVGFCTVKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNA 2603
Query: 340 EFTYQLDD----PKGAFSIDPRSGWLTVRNQTV 368
+ TY +++ + ++P +G ++V+ V
Sbjct: 2604 DVTYTVEEADEVTEDIIEVNPFTGVVSVKESLV 2636
Score = 60.9 bits (141), Expect = 3e-07
Identities = 77/333 (23%), Positives = 138/333 (41%), Gaps = 26/333 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE-EGVP-FAVEERSGV 628
P F+ + YE V + + I +DA + + Y + E + F +++RSGV
Sbjct: 1436 PMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGV 1495
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ + ++L + + + + VHV D ND L + II +
Sbjct: 1496 LVLKEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISN 1555
Query: 688 VKENSAGA----AIGQIFHTNMSSIYG-NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
+ A+ + +N +Y + GNV Q G+I
Sbjct: 1556 LALTGTEVLRVKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGT---------GSIRVSD 1606
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDR ++ Y +TV A ++G + + VTI I+ PP F Y I E
Sbjct: 1607 ALDRLPQEHYHLTVKAT-DQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPP 1665
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
G+ + + A ++ L+ G+ F ++ N+G++ + ++LD E+ Y
Sbjct: 1666 GSPVL------SVSARCPSSVLYRINE-GDPNGTFHININSGLLS-VKNALDFEQHSSYH 1717
Query: 863 LSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
L + A +T G+SS+A + + + D NDN P F+Q
Sbjct: 1718 LQISATNTAGISSDAVVFVYVIDANDNAPVFHQ 1750
Score = 59.7 bits (138), Expect = 6e-07
Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + V D ND P+F Y+ ++E + L +V ATDAD G NA Y +
Sbjct: 128 VLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSF--TTRS 185
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
PF + P TG +++ LD D+Y LTV+A D
Sbjct: 186 HPFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAED 219
Score = 59.3 bits (137), Expect = 8e-07
Identities = 54/171 (31%), Positives = 76/171 (44%), Gaps = 13/171 (7%)
Query: 218 IHAIDQDLGVGATLRYELISG-NDRKLFSLDSVNGSLFLEKELD-LDAEHNLQANTFVLQ 275
+ A+D+D G A + Y SG N F +D GS+ + LD L EH + L
Sbjct: 1566 VKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEH------YHLT 1619
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ P ++A V I + P F Y I E +P G VL V A
Sbjct: 1620 VKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSVSARCP-- 1677
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ + DP G F I+ SG L+V+N LD E HSS +++ A T
Sbjct: 1678 -SSVLYRINEGDPNGTFHININSGLLSVKN--ALDFEQHSSYHLQISATNT 1725
Score = 59.3 bits (137), Expect = 8e-07
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 15/172 (8%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D A L Y+++ ++F +D G++ L+ +D +A F
Sbjct: 1774 PLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMGTISLKSLIDFEATPE-----FFF 1828
Query: 275 QVQASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VQ P +A +V I +LD ND P+F + Y I++ + V+QV A D
Sbjct: 1829 SVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALTWPVFQDMKVIQVTAHD 1888
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
D TY + + K AF ID +G ++V + + L ++H+ L++ +
Sbjct: 1889 ADSA----VTYMILENSNKNAFKIDQSTGVISVNDSSEL--QSHNELKITAF 1934
Score = 58.0 bits (134), Expect = 2e-06
Identities = 97/412 (23%), Positives = 167/412 (40%), Gaps = 59/412 (14%)
Query: 990 RYFVINERHGHV----IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
RYF INE G + + R+L P + L ++ DG V + + + N + P F
Sbjct: 2410 RYFAINESSGLISFSNVCKRNLDPF--YNLTVAVSDGV-FQKTAPVNIDMTNGNKYSPYF 2466
Query: 1046 KKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
+ Y ++ E A+ RV+ ++ A D D G ++ Y I D F I+ G +
Sbjct: 2467 TQNIYEADLAENAEVGTRVI-RLAAIDPDDGPYGSVDYTIINKLADEKFAINE-DGQIVT 2524
Query: 1105 NGELDRETEDKYILT--VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH 1162
+ LDRE + ++ ++A+D G D NDN P+F A + +
Sbjct: 2525 SQPLDRENPSQRVIAIKIMAKDGG---GRVGFCTVKIILTDENDNVPQFKASE------Y 2575
Query: 1163 PEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG----NGNGLILYSL 1218
+ + + + V+ I Y A +NA + TV + D I G + SL
Sbjct: 2576 DISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSVKESL 2635
Query: 1219 PQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
+N+ ++ G P +S+ + V V VP E+ + P F Y E++
Sbjct: 2636 VGLENKIFNFKVKARDGGFPFYNSSVPVQVKV--VPPEIIL---PRFTEPLYSFSASEDL 2690
Query: 1271 NAPVELVSLNLTEHYENFKMRYYILNENDTDIRR--TFVIDPRNGTLYLVRSPDREVKDT 1328
E+ ++ + + Y ++N N D + +F ID GT+ L + D E
Sbjct: 2691 PIGYEIGTVKAD---ADMPLIYSLVNGNTLDSNKELSFAIDKDGGTVVLQNNIDHEKTKM 2747
Query: 1329 YEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
Y++ V A+ + + V V + ++DVNDN P F
Sbjct: 2748 YKIDVIAQGNHNGTNVASL----------------VSVHIEVQDVNDNKPMF 2783
Score = 55.6 bits (128), Expect = 1e-05
Identities = 118/502 (23%), Positives = 199/502 (39%), Gaps = 65/502 (12%)
Query: 989 KRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
K F I++ G + V S +S L I+A DG D V++ + + F+
Sbjct: 1903 KNAFKIDQSTGVISVNDSSELQSHNELKITAFDG-LYKDTTVVKLNITNATKSSLKFEDR 1961
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG-E 1107
+ V E + ++L + AT + T + P F + P +GVL G
Sbjct: 1962 AHVATVLENSTSVKILVVLRATGTYLNEPLQFTV-LNPHGK---FAVIPSSGVLHTTGVP 2017
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
DRE +D Y + V RD DVNDN P E+L P+
Sbjct: 2018 FDREEQDVYDVAVEVRDF-RSPPRVDVTHVKVYIDDVNDNVP------EILNL--PKTLL 2068
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
+S+ ++ V AT + G + +F+ + DF G I L Q+ L
Sbjct: 2069 ISDETEPGDVLFQVL-ATDND---FGENGSIIFSLEDDF---GLFRIDLYLGDVSLQRPL 2121
Query: 1228 GLPSLSSTAILMVTVAD-----------VPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
S++ +L V V+D + +V+ P+F S YY L++ EN+ +
Sbjct: 2122 DFESMNKY-VLTVLVSDDGQPSLSAIGTIYIQVQNRSHPIFQSMYYPLKLPENITPFTTI 2180
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ + + E +++ Y + +N + R F ID + G L V D +
Sbjct: 2181 LHVQ-ARNPEGYRLIYNLEEDNAS---RLFNIDFKTGVL--------SVTDFLD------ 2222
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
+ E H++ A D + G T + KV + ++D+NDN+P F N V + P
Sbjct: 2223 ---FESETKHILTVRATDSVSG-TFAEAKVEIDVEDINDNAPVFQ--NLSYVADVFEGLP 2276
Query: 1397 FGYQVMQLKGA-IGHHPTASRTVRADTDELVFFERLSLNG-LTSPQATDSDIGINADIRY 1454
G V+Q+ A T + E FFE L+G L + Q D + ++
Sbjct: 2277 IGTSVLQVSAVDRDADKNAEATYQLIDKESHFFEIDPLSGVLVTTQVLDYESTQQFTLKV 2336
Query: 1455 QILNEQAPRFAIDPVSGTVRVV 1476
+ ++ P P+SG ++
Sbjct: 2337 KATDKGVP-----PLSGEAHII 2353
Score = 54.0 bits (124), Expect = 3e-05
Identities = 52/198 (26%), Positives = 82/198 (41%), Gaps = 13/198 (6%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-----GPSLTIP 131
+S+ + VTV + DVNDN P+F + + V E G L+ GP +
Sbjct: 3392 LSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTDRDTPQNGPPFSFH 3451
Query: 132 LTV---PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+ R I + + H + D GH L S + + +
Sbjct: 3452 IVSGNEDRSFHIDQGGLLSVSSQLRRRGKPQHLLKIQVTDSGHPPLSSICVVKINITEQS 3511
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS-GNDRKLFSLD 247
Y ++ I +G I K ++ +HA DQD L Y+L+S G D+ LFS+D
Sbjct: 3512 RYPPTVNPLEIFITTAGGPILKSVI--SKLHATDQD--PQDVLSYKLVSEGQDKGLFSVD 3567
Query: 248 SVNGSLFLEKELDLDAEH 265
+V+G + +EK LD H
Sbjct: 3568 TVDGKIVVEKNLDPGLYH 3585
Score = 53.2 bits (122), Expect = 5e-05
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ + + + V+ +P + V++ + D+NDN+PE + I + G + Q
Sbjct: 2022 EQDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQ 2081
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
V+ATD D GENG + L+D G F ID G V Q LD E+ + + V +
Sbjct: 2082 VLATDNDFGENGSIIFSLEDDFGLFRIDLYLG--DVSLQRPLDFESMNKYVLTVLVSDDG 2139
Query: 388 P---SVVGT 393
S +GT
Sbjct: 2140 QPSLSAIGT 2148
Score = 48.4 bits (110), Expect = 0.002
Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 10/124 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +LD ND P+F P++ Y +K + + + + +V A D D+G N Y S
Sbjct: 128 VLIQVLDTNDLKPLFYPAS-YHVVIKEDTPIKSSLVRVSATDADIGSNAEFYY-----SF 181
Query: 505 LTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPS--ERRYSLAVVTIEVT 560
T + PF ++P TGTV++ + R+ L V A D+ S ++ ++A V +++
Sbjct: 182 TTRSHPFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQKFGNVATVVVKIQ 241
Query: 561 RGTK 564
+ K
Sbjct: 242 KVEK 245
Score = 45.6 bits (103), Expect = 0.011
Identities = 56/205 (27%), Positives = 94/205 (45%), Gaps = 19/205 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S V V VT+ D NDN P+F N + ++ VG+ I ++ D D QNG
Sbjct: 3389 DPPLSSAVQVTVTVSDVNDNPPMFSKIN-HSLIVQEGEAVGSGILQLLVTDRDTPQNGPP 3447
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
+ S S F I+ G +SV+ G+ H L ++ +D P S+
Sbjct: 3448 -FSFHIVSGNEDRS-FHIDQG-GLLSVSSQLRRRGKPQHLLKIQVTDSGHPPLS---SIC 3501
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG--IGTSVGQIRVNDAFEQNDVSYDLL 611
VV I +T ++ P + P E ++ + G + + + ++ D Q+ +SY L+
Sbjct: 3502 VVKINITEQSR-YPPTV-----NPLEIFITTAGGPILKSVISKLHATDQDPQDVLSYKLV 3555
Query: 612 -HGYEEGVPFAVEERSGVITVVDDL 635
G ++G+ F+V+ G I V +L
Sbjct: 3556 SEGQDKGL-FSVDTVDGKIVVEKNL 3579
Score = 45.2 bits (102), Expect = 0.014
Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 17/182 (9%)
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV--KENS 692
L+R R +Y A + + T + V+D ND LK P +HV KE++
Sbjct: 101 LNREVRDIYTLTVEATESTFDNRARTKVLIQVLDTND-----LKPLFYPASYHVVIKEDT 155
Query: 693 A-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDV 751
+++ ++ T+ + I N F + D GT+ K LD +RD
Sbjct: 156 PIKSSLVRVSATD-ADIGSNAEFYYSFTTRSHPFAVDPFT----GTVTLVKRLDTSQRDR 210
Query: 752 YRMTVIAEFNKGVISG----AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
Y +TV+AE K ISG + V + I+ N + T E + + KI IK
Sbjct: 211 YDLTVLAEDRKKKISGVQKFGNVATVVVKIQKVEKNFTLISPTTAESLLTIDDKISVNIK 270
Query: 808 MD 809
M+
Sbjct: 271 ME 272
Score = 43.2 bits (97), Expect = 0.056
Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 23/163 (14%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEK--ELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
L+Y+++SGN+ + F+++ +G + + +LD +NL T + Q KTA
Sbjct: 2399 LQYKILSGNEGRYFAINESSGLISFSNVCKRNLDPFYNL---TVAVSDGVFQ-----KTA 2450
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY----Q 344
V I++ + N P F + Y + EN G V+++ A D D G G Y +
Sbjct: 2451 P--VNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINK 2508
Query: 345 LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSS--LRMKVYAKE 385
L D K A + D + V +Q LDRE S + +K+ AK+
Sbjct: 2509 LADEKFAINEDGQ----IVTSQP-LDRENPSQRVIAIKIMAKD 2546
Score = 40.3 bits (90), Expect = 0.40
Identities = 33/168 (19%), Positives = 75/168 (44%), Gaps = 13/168 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L +++I G++ + F ++ GS+ + L+ + + ++ + +T
Sbjct: 1371 LLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTV--------RVTDGFQTITT 1422
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPK 349
+ I+++D+N++ P F Y + + E+ +L + A D D ++ +P+
Sbjct: 1423 QAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPE 1482
Query: 350 GA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
F +D RSG L ++ + LD E S+ + V ++ + FA
Sbjct: 1483 SLKYFHLDQRSGVLVLKEE--LDYETISTHTLIVMVRDDKIPIKKNFA 1528
Score = 39.9 bits (89), Expect = 0.53
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 1254 KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNG 1313
KP+F Y + I+E+ LV ++ T+ +Y + T F +DP G
Sbjct: 139 KPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYY---SFTTRSHPFAVDPFTG 195
Query: 1314 TLYLVRSPDREVKDTYEVIVRAERQK 1339
T+ LV+ D +D Y++ V AE +K
Sbjct: 196 TVTLVKRLDTSQRDRYDLTVLAEDRK 221
Score = 39.9 bits (89), Expect = 0.53
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 1434 NGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAAL 1479
+ L ATD+DIG NA+ Y P FA+DP +GTV +V L
Sbjct: 159 SSLVRVSATDADIGSNAEFYYSFTTRSHP-FAVDPFTGTVTLVKRL 203
Score = 37.9 bits (84), Expect = 2.1
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
Q+ ++ V V +ED+NDN P F+ T Y + V E P G
Sbjct: 896 QLFSFTDVVVVLEDINDNPPKFVPTVYKIKVPEDVPPG 933
Score = 37.1 bits (82), Expect = 3.7
Identities = 15/40 (37%), Positives = 26/40 (65%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALA 1480
A D D GIN+++RY + + F++D +SG +R+ +LA
Sbjct: 3122 AKDPDTGINSEVRYSLQGADSGFFSLDEISGVLRLERSLA 3161
Score = 36.3 bits (80), Expect = 6.5
Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 151 KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHK 210
K T N V YSI+SGN+DG F + + +L ++ LD++ + + V A GK +
Sbjct: 3230 KDATENEPVRYSIISGNEDGRFMI-NPVTGLLSVKAALDFERCREYYLSVEGARGKPLLS 3288
Query: 211 EI 212
+I
Sbjct: 3289 DI 3290
>UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio
"Protocadherin2-gamma-v12-A.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Protocadherin2-gamma-v12-A.
- Takifugu rubripes
Length = 1441
Score = 147 bits (356), Expect = 2e-33
Identities = 180/740 (24%), Positives = 314/740 (42%), Gaps = 65/740 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ Q+ + + V +LD NDN PVF +Y+ ++ NA GT+I KV A D D G +G V
Sbjct: 191 EPQMTGTMRIYVAVLDVNDNAPVFTKP-VYKANIAENAVRGTLITKVSASDADKGSHGEV 249
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSL 552
Y + + + ++ F +N + G V + PI E + + VEA D + +
Sbjct: 250 SYVIANSMD-PASNLFHVN-SEGDV-ILNGPIDYEREKHYDIDVEAIDSGGLSDSSKIII 306
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V+ + NKP I + + A V + + T + + VND +N+ +
Sbjct: 307 DVIDVN------DNKPTI-NIISASGS--VTEDSALKTVIALMSVNDPDSENNGKVQCM- 356
Query: 613 GYEEGVPFAVEERSG-VITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVD 668
E +PF ++ S V +++ + L R Y+ E +LS T+ + D
Sbjct: 357 -INENIPFEIKFTSNNVYSLLTERELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISD 415
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQ 724
VND V + ++ I V+ N+ G ++ F N V +++ N
Sbjct: 416 VNDNPPVFERSSYEAYI--VENNTPGLSV---FTVKARDTDWNQNARVSYILEDSSVNGV 470
Query: 725 DVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
V+ ++++ D G + + D E+ + V A+ + + V I I+D+NDN
Sbjct: 471 PVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNV-SVKILIQDQNDN 529
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG---KEMFDVD 840
PP + G M + + + A D D G NAL YT+ + ++ +++
Sbjct: 530 PPQVLYPVQTGGSMVAEMVPRSADV-GYLSAEDPDVGINALKAYTISKDDCFTLKIKEIE 588
Query: 841 ENTGVVKFI-GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
V + + SLDREKK ++ L L A D G S A++ + + D ND +
Sbjct: 589 NGRKVPELVLNKSLDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVLDVNDQCSRI-RTY 647
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALD 957
+K + H + + + +I++ + P I E+ G+ + + A D
Sbjct: 648 IFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNP---IREDAQRGSVVALIRARD 704
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI 1017
DSG NG++ + S + Y ++ V+ ++ SE+ + I
Sbjct: 705 EDSGNNGKVMLHLPKD-----SPFTLKPSFGNNYALVT---SGVLDRETI---SEYNIEI 753
Query: 1018 SALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
+A D G+ L+ + V + DVND+ PVF + YN ++E +L V A+D DFG
Sbjct: 754 TATDSGSPPLSSKKIIPVSITDVNDNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDFG 813
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL------DRETEDKYILTVVARDNGXXX 1129
+NA ++Y I S +S + S NG + D E + + V A+D G
Sbjct: 814 ENAKISYSILDSKVQ-DVSVSSYVYINSDNGSIYSMHSFDYEKLKVFQIRVQAKDQG-SP 871
Query: 1130 XXXXXXXXXXXXXDVNDNSP 1149
D NDN+P
Sbjct: 872 SLSSNTTVHVFILDQNDNAP 891
Score = 129 bits (311), Expect = 7e-28
Identities = 123/467 (26%), Positives = 210/467 (44%), Gaps = 42/467 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V VE+T D NDN PVF F + +A VG+ KA+DPD+G NG+ Y L+ +
Sbjct: 91 VTVEIT--DINDNAPVFQKEEK-RFEISESAIVGSKFMLEKAIDPDIGMNGLQRYTLKPS 147
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRH---ALFVEASD--QPANPSERRYSLAVVTI 557
N + + + + + + P+ + +L + A D +P R +AV+ +
Sbjct: 148 DNFVLKLHTESDGDKKVEMILQKPLDREKQEHISLLLTAEDGGEPQMTGTMRIYVAVLDV 207
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYE 615
+ P F Y+ + N GT + ++ +DA + +VSY + + +
Sbjct: 208 N---------DNAPVFTKPVYKANIAENAVRGTLITKVSASDADKGSHGEVSYVIANSMD 258
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
G + + + YD + A+ ++ LS + + V+DVND +
Sbjct: 259 PASNLFHVNSEGDVILNGPIDYEREKHYDIDVEAI-DSGGLSDSSKIIIDVIDVNDNKPT 317
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ + S V E+SA + + N NG V+ +I +++ +I +
Sbjct: 318 INIISASG---SVTEDSALKTVIALMSVNDPDSENNG--KVQCMI--NENIPFEIKFTSN 370
Query: 736 G--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++ T++ LDRE+ Y +TV ++GV S + +T+ I D NDNPPVFE ++YE
Sbjct: 371 NVYSLLTERELDRERESEYNITVSCS-DEGVPSLSSSVTLTLQISDVNDNPPVFERSSYE 429
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENTGVVK 847
+I+EN+ G + +KA D D NA Y L V ++GVV
Sbjct: 430 AYIVENNTPGLSV---FTVKARDTDWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVVH 486
Query: 848 FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+ S D E+ + + A+D G LSS + I+I D+NDN P+
Sbjct: 487 AV-RSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQ 532
Score = 89.8 bits (213), Expect = 5e-16
Identities = 72/248 (29%), Positives = 115/248 (46%), Gaps = 20/248 (8%)
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIA 721
TV + D+ND V K F + E+ A +G F + G G R+ +
Sbjct: 92 TVEITDINDNAPVFQKEEKR---FEISES---AIVGSKFMLEKAIDPDIGMNGLQRYTLK 145
Query: 722 NQQDVTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ + DG + QKPLDREK++ + + AE + G G ++ + +
Sbjct: 146 PSDNFVLKLHTESDGDKKVEMILQKPLDREKQEHISLLLTAE-DGGEPQMTGTMRIYVAV 204
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GK 834
D NDN PVF Y+ I EN+ GT I + A+DAD+G++ Y +
Sbjct: 205 LDVNDNAPVFTKPVYKANIAENAVRGTLITK---VSASDADKGSHGEVSYVIANSMDPAS 261
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
+F V+ V+ + +D E++ Y + + A D+GGLS +++II + D NDNKP N
Sbjct: 262 NLFHVNSEGDVI--LNGPIDYEREKHYDIDVEAIDSGGLSDSSKIIIDVIDVNDNKPTIN 319
Query: 895 QIEENSKV 902
I + V
Sbjct: 320 IISASGSV 327
Score = 88.2 bits (209), Expect = 2e-15
Identities = 106/421 (25%), Positives = 179/421 (42%), Gaps = 48/421 (11%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN-SEVYIPPSKLSADALEVKRYFVINE 996
F I E+ +G+ + A+D D G+NG RY S+ ++ +D +
Sbjct: 112 FEISESAIVGSKFMLEKAIDPDIGMNGLQRYTLKPSDNFVLKLHTESDG----------D 161
Query: 997 RHGHVIVARSLPPESEFRLNI--SALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNF 1052
+ +I+ + L E + +++ +A DGG ++R++V DVND+ PVF K Y
Sbjct: 162 KKVEMILQKPLDREKQEHISLLLTAEDGGEPQMTGTMRIYVAVLDVNDNAPVFTKPVYKA 221
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLPFEISPLTGVLSVNGELDR 1110
N+ E ++ KV A+DAD G + ++Y I S F ++ G + +NG +D
Sbjct: 222 NIAENAVRGTLITKVSASDADKGSHGEVSYVIANSMDPASNLFHVNS-EGDVILNGPIDY 280
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E E Y + V A D+G DVNDN P E L
Sbjct: 281 EREKHYDIDVEAIDSG---GLSDSSKIIIDVIDVNDNKPTINIIS--ASGSVTEDSALKT 335
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL 1227
+ ++ V E N + + + + F N +L +R+++ N+
Sbjct: 336 ----VIALMSVNDPDSENNGKVQCMINENIPFEIKFTSNNVYSLLTERELDRERESEYNI 391
Query: 1228 -------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP---VELV 1277
G+PSLSS+ L + ++DV D + PVF YE I EN N P V V
Sbjct: 392 TVSCSDEGVPSLSSSVTLTLQISDVND-----NPPVFERSSYEAYIVEN-NTPGLSVFTV 445
Query: 1278 SLNLTEHYENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
T+ +N ++ Y + + N + + +G ++ VRS D E + +V+A
Sbjct: 446 KARDTDWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKA 505
Query: 1336 E 1336
+
Sbjct: 506 Q 506
Score = 75.4 bits (177), Expect = 1e-11
Identities = 70/235 (29%), Positives = 103/235 (43%), Gaps = 28/235 (11%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F P EN GT I K++A D D G +G++ Y + + P S L
Sbjct: 205 LDVNDNAPVFTKPVYKANIAENAVRGTLITKVSASDADKGSHGEVSYVIANSMD-PASNL 263
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVN 1039
F +N G VI+ + E E + +++ A+D G L+D+ + + V DVN
Sbjct: 264 ----------FHVNSE-GDVILNGPIDYEREKHYDIDVEAIDSGGLSDSSKIIIDVIDVN 312
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI---S 1096
D+ P + +V E + V+ + D D N + I + ++PFEI S
Sbjct: 313 DNKPTINIISASGSVTEDSALKTVIALMSVNDPDSENNGKVQCMI---NENIPFEIKFTS 369
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L ELDRE E +Y +TV D G DVNDN P F
Sbjct: 370 NNVYSLLTERELDRERESEYNITVSCSDEG-VPSLSSSVTLTLQISDVNDNPPVF 423
Score = 66.9 bits (156), Expect = 4e-09
Identities = 105/451 (23%), Positives = 181/451 (40%), Gaps = 63/451 (13%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+++ N P G ++ + A D D N ++ Y S + + V Y ++
Sbjct: 431 YIVENNTP-GLSVFTVKARDTDWNQNARVSYILEDS--------SVNGVPVSSYVSVSAD 481
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFP--VFKKTWYN 1051
G V RS E +F + A DGG+ L+ N+SV++ ++D ND+ P ++
Sbjct: 482 SGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGG 541
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL----PFEISPLTGVLSVNGE 1107
V E +G + A D D G NA Y I D E L +N
Sbjct: 542 SMVAEMVPRSADVGYLSAEDPDVGINALKAYTISKDDCFTLKIKEIENGRKVPELVLNKS 601
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE + + L + A D G DVND + + + HP+ +
Sbjct: 602 LDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVL-DVNDQCSRIRTYIFAKDKGHPQMEG 660
Query: 1168 LS---------NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
N N +++ V I E+A G+ VA + A D D GN NG ++ L
Sbjct: 661 HCRVQIMVIDINDNAPEIILTSVPNP-IREDAQRGSVVALIRARDED-SGN-NGKVMLHL 717
Query: 1219 PQRK-------------------------NQQNLGLPSLSSTAILMVTVADVPDEV-EMS 1252
P+ ++ N+ + + S + + + +P + +++
Sbjct: 718 PKDSPFTLKPSFGNNYALVTSGVLDRETISEYNIEITATDSGSPPLSSKKIIPVSITDVN 777
Query: 1253 DK-PVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNE--NDTDIRRTFV 1307
D PVF Y + ++EN + + VS + + EN K+ Y IL+ D +
Sbjct: 778 DNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDFGENAKISYSILDSKVQDVSVSSYVY 837
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
I+ NG++Y + S D E +++ V+A+ Q
Sbjct: 838 INSDNGSIYSMHSFDYEKLKVFQIRVQAKDQ 868
Score = 65.7 bits (153), Expect = 9e-09
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + Y L L D E LD + Q + +L + A
Sbjct: 1282 AQDPDVGSNSVKSYTLSKDECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLL-LTAI 1340
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP+KT + + +LD NDN+P F+ YNIS+ EN +L+V ATD D+G NG
Sbjct: 1341 DGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNG 1400
Query: 340 EFTYQLDD 347
E Y +
Sbjct: 1401 EIEYSFPE 1408
Score = 65.3 bits (152), Expect = 1e-08
Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 7/182 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D+G+ RY L ++ L +G +E L + Q + +L + A
Sbjct: 129 AIDPDIGMNGLQRYTLKPSDNFVLKLHTESDGDKKVEMILQKPLDREKQEHISLL-LTAE 187
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P T R+ + +LD+NDN P F Y +I EN G + +V A+D D+G +G
Sbjct: 188 DGGEPQMTGTMRIYVAVLDVNDNAPVFTKPVYKANIAENAVRGTLITKVSASDADKGSHG 247
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQ-TVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
E +Y + A S+DP S V ++ V+ R K Y + G +DS
Sbjct: 248 EVSYVI-----ANSMDPASNLFHVNSEGDVILNGPIDYEREKHYDIDVEAIDSGGLSDSS 302
Query: 399 RI 400
+I
Sbjct: 303 KI 304
Score = 65.3 bits (152), Expect = 1e-08
Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+ L ++A+DGGN ++ V V D ND+ PVF+K YN ++ E T VL KV
Sbjct: 1330 QDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKV 1389
Query: 1068 DATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ATDAD G N + Y P D F + TG + + G+LD E Y
Sbjct: 1390 EATDADEGVNGEIEYSFPEHTPQDILSVFRLDSSTGEIFLVGQLDYEKSIMY 1441
Score = 63.7 bits (148), Expect = 4e-08
Identities = 48/143 (33%), Positives = 72/143 (50%), Gaps = 14/143 (9%)
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
+D++ D I E + K LDREK+D + + + A + G G + + + D NDN
Sbjct: 1308 KDLSGDRQIPE---LVLDKTLDREKQDSHHLLLTA-IDGGNPVKTGTTTIIVTVLDNNDN 1363
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFD 838
PVF+ Y + ENS + + ++ATDADEG N Y+ F E +F
Sbjct: 1364 VPVFQKPLYNISLPENSSTSSVLLK---VEATDADEGVNGEIEYS-FPEHTPQDILSVFR 1419
Query: 839 VDENTGVVKFIGDSLDREKKIMY 861
+D +TG + +G LD EK IMY
Sbjct: 1420 LDSSTGEIFLVG-QLDYEKSIMY 1441
Score = 60.1 bits (139), Expect = 5e-07
Identities = 54/218 (24%), Positives = 98/218 (44%), Gaps = 19/218 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ + T I ++ D DS NG+++ N + P ++ + V Y ++ ER
Sbjct: 327 VTEDSALKTVIALMSVNDPDSENNGKVQCMINENI---PFEIKFTSNNV--YSLLTERE- 380
Query: 1000 HVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
ESE+ + +S D G +L+ ++++ + + DVND+ PVF+++ Y + E
Sbjct: 381 -----LDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSYEAYIVEN 435
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP----FEISPLTGVLSVNGELDRET 1112
+ V A D D+ QNA ++Y ++ S + +P +S +GV+ D E
Sbjct: 436 NTPGLSVFTVKARDTDWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQ 495
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ V A+D G D NDN P+
Sbjct: 496 IKDFHFLVKAQDGG-SPPLSSNVSVKILIQDQNDNPPQ 532
Score = 59.7 bits (138), Expect = 6e-07
Identities = 47/166 (28%), Positives = 74/166 (44%), Gaps = 9/166 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + ++ +DRE F + + ++ VT+ I D NDN PVF+
Sbjct: 54 GALLVKEKIDREALCRQTTPCALHFQVTLENPLELFPVTVEITDINDNAPVFQKEEKRFE 113
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGD 851
I E++ +G++ ++ KA D D G N L YTL K + D + V +
Sbjct: 114 ISESAIVGSKFMLE---KAIDPDIGMNGLQRYTLKPSDNFVLKLHTESDGDKKVEMILQK 170
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LDREK+ L L A D G ++ + + + D NDN P F +
Sbjct: 171 PLDREKQEHISLLLTAEDGGEPQMTGTMRIYVAVLDVNDNAPVFTK 216
Score = 57.6 bits (133), Expect = 2e-06
Identities = 52/198 (26%), Positives = 90/198 (45%), Gaps = 19/198 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G+ + ++A DLD G N +I Y I SK+ + V Y IN +G
Sbjct: 792 LKENGVPGSILYSVSASDLDFGENAKISYS------ILDSKVQD--VSVSSYVYINSDNG 843
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFP--VFKKTWYNFN 1053
+ S E F++ + A D G+ L+ N +V VF+ D ND+ P ++ + +
Sbjct: 844 SIYSMHSFDYEKLKVFQIRVQAKDQGSPSLSSNTTVHVFILDQNDNAPAVIYPSSAALGS 903
Query: 1054 VEEAQYTR-----RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+ + R +L KV A DAD G NA ++Y + + F ++ TG + +
Sbjct: 904 LSHQRMPRSAKAGHLLTKVTAVDADSGHNAWISYRLAEATDASLFTVNQYTGEVRTKRAV 963
Query: 1109 DRETEDKYILTVVARDNG 1126
+ + L + +D+G
Sbjct: 964 SEQDDSSQRLLIEIKDDG 981
Score = 55.2 bits (127), Expect = 1e-05
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
SL E+ELD + E + + + V S P ++ + +++ D+NDN P FE Y
Sbjct: 374 SLLTERELDRERE-----SEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSY 428
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
IVEN G SV V A D D +N +Y L+D
Sbjct: 429 EAYIVENNTPGLSVFTVKARDTDWNQNARVSYILED 464
Score = 55.2 bits (127), Expect = 1e-05
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
VT+LD NDN PVF LY S+ N+ +V+ KV+A D D G NG + Y +
Sbjct: 1355 VTVLDNNDNVPVF-QKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQD 1413
Query: 507 ITSPFKINPNTGTV 520
I S F+++ +TG +
Sbjct: 1414 ILSVFRLDSSTGEI 1427
Score = 51.2 bits (117), Expect = 2e-04
Identities = 51/180 (28%), Positives = 81/180 (45%), Gaps = 13/180 (7%)
Query: 223 QDLGVGAT----LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
+DLG+G + + + + ++ FS+D+ G L + +D +A Q+ + VL +Q
Sbjct: 1175 KDLGLGLSDIFDRKLRVAAEAGKQYFSVDAGKGELVVNDRIDREALCG-QSASCVLTLQV 1233
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
NPL+ R+E+E+ D+NDN P F + I E+ G L A D D G N
Sbjct: 1234 VT-ENPLQLH--RIEVEIKDINDNYPNFLTGERFLKIAESTAAGVRFLLETAQDPDVGSN 1290
Query: 339 GEFTYQLD-DPKGAFSIDPRSGWLTVRN---QTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+Y L D + + SG + LDRE S + + A + NP GT
Sbjct: 1291 SVKSYTLSKDECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGT 1350
Score = 50.0 bits (114), Expect = 5e-04
Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
N Q + + A +P RV+I ++D+NDN PE + I E+ G V
Sbjct: 638 NDQCSRIRTYIFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNPIREDAQRGSVV 697
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGA-FSIDPRSG-WLTVRNQTVLDREAHSSLRMKVYA 383
+ A D+D G NG+ L PK + F++ P G + VLDRE S +++ A
Sbjct: 698 ALIRARDEDSGNNGKVMLHL--PKDSPFTLKPSFGNNYALVTSGVLDRETISEYNIEITA 755
Query: 384 KET 386
++
Sbjct: 756 TDS 758
Score = 50.0 bits (114), Expect = 5e-04
Identities = 41/134 (30%), Positives = 69/134 (51%), Gaps = 13/134 (9%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGF--IMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
++++ + I+D NDN P F T E F I E++ G ++ A D D G+N++ Y
Sbjct: 1241 LHRIEVEIKDINDNYPNF--LTGERFLKIAESTAAGVRFLLET---AQDPDVGSNSVKSY 1295
Query: 828 TLFGE---GKEMFDVDENTGVVKFIGD-SLDREKKIMYKLSLVARDTGG--LSSEAELII 881
TL + +M D+ + + + + D +LDREK+ + L L A D G + +I+
Sbjct: 1296 TLSKDECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIV 1355
Query: 882 MIGDENDNKPEFNQ 895
+ D NDN P F +
Sbjct: 1356 TVLDNNDNVPVFQK 1369
Score = 49.2 bits (112), Expect = 9e-04
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 5/125 (4%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT- 1089
V V + D+ND+ PVF+K F + E+ A D D G N Y ++PSD
Sbjct: 91 VTVEITDINDNAPVFQKEEKRFEISESAIVGSKFMLEKAIDPDIGMNGLQRYTLKPSDNF 150
Query: 1090 --DLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
L E V + + LDRE ++ L + A D G DVND
Sbjct: 151 VLKLHTESDGDKKVEMILQKPLDREKQEHISLLLTAEDGG-EPQMTGTMRIYVAVLDVND 209
Query: 1147 NSPKF 1151
N+P F
Sbjct: 210 NAPVF 214
Score = 49.2 bits (112), Expect = 9e-04
Identities = 23/76 (30%), Positives = 42/76 (55%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+++ A+ +P +++ + + + D+NDN P F YN+ + EN G + V A+D
Sbjct: 751 IEITATDSGSPPLSSKKIIPVSITDVNDNPPVFTQPSYNVYLKENGVPGSILYSVSASDL 810
Query: 334 DQGENGEFTYQLDDPK 349
D GEN + +Y + D K
Sbjct: 811 DFGENAKISYSILDSK 826
Score = 47.2 bits (107), Expect = 0.003
Identities = 40/110 (36%), Positives = 50/110 (45%), Gaps = 11/110 (10%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPSN-----LYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
L S V V +LD NDN P V PS+ L M +AK G ++ KV AVD D G N
Sbjct: 873 LSSNTTVHVFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGHN 932
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASD 540
+ Y R + T S F +N TG V A S + L +E D
Sbjct: 933 AWISY---RLAEATDASLFTVNQYTGEVRTKRAVSEQDDSSQRLLIEIKD 979
Score = 46.8 bits (106), Expect = 0.005
Identities = 72/312 (23%), Positives = 123/312 (39%), Gaps = 21/312 (6%)
Query: 221 IDQDLGVGATL----RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I QDLG+ + + +G+ + L+ G+L +++++D +A Q L
Sbjct: 20 IAQDLGIDVKRLNSGKARIYTGDSVQYVELNRGRGALLVKEKIDREALCR-QTTPCALHF 78
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
Q + L NPL+ V +E+ D+NDN P F+ + I E+ G + A D D G
Sbjct: 79 QVT-LENPLELFP--VTVEITDINDNAPVFQKEEKRFEISESAIVGSKFMLEKAIDPDIG 135
Query: 337 ENGEFTYQLDDPKGAFSI---DPRSGWLTVRN--QTVLDREAHSSLRMKVYAKE-TNPSV 390
NG Y L P F + G V Q LDRE + + + A++ P +
Sbjct: 136 MNGLQRYTL-KPSDNFVLKLHTESDGDKKVEMILQKPLDREKQEHISLLLTAEDGGEPQM 194
Query: 391 VGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLL 450
GT + P+ K GT + D S + EV+ +
Sbjct: 195 TGTMRIYVAVLDVNDNAPVFTKPVYKANIAENAVRGTLITKVSASDADKGS--HGEVSYV 252
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
AN +P SNL+ + + + + I + D+ + L +S + I
Sbjct: 253 IANSMDPA---SNLFHVNSEGDVILNGPIDYEREKHYDIDVEAIDSGGLSDSSKI-IIDV 308
Query: 511 FKINPNTGTVSV 522
+N N T+++
Sbjct: 309 IDVNDNKPTINI 320
Score = 46.0 bits (104), Expect = 0.008
Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 21/182 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGN--DRKLFS---LDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D G A + Y ++ D + S ++S NGS++ D + + F
Sbjct: 805 VSASDLDFGENAKISYSILDSKVQDVSVSSYVYINSDNGSIYSMHSFDYE-----KLKVF 859
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF----EVDFYNIS---IVENLPNGFSV 325
++VQA +P ++ V + +LD NDN P ++S + + G +
Sbjct: 860 QIRVQAKDQGSPSLSSNTTVHVFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLL 919
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+V A D D G N +Y+L + A F+++ +G VR + + + SS R+ +
Sbjct: 920 TKVTAVDADSGHNAWISYRLAEATDASLFTVNQYTG--EVRTKRAVSEQDDSSQRLLIEI 977
Query: 384 KE 385
K+
Sbjct: 978 KD 979
Score = 39.9 bits (89), Expect = 0.53
Identities = 55/224 (24%), Positives = 94/224 (41%), Gaps = 24/224 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ IPE + G+ + L A DL GL S+++ +++A+A K+YF ++
Sbjct: 1158 YSIPEELKQGSVVGNL-AKDLGLGL---------SDIFDRKLRVAAEA--GKQYFSVDAG 1205
Query: 998 HGHVIVARSLPPESEFRLNISA-LDGGNLNDNI----SVRVFVKDVNDHFPVFKKTWYNF 1052
G ++V + E+ + S L + +N + V +KD+ND++P F
Sbjct: 1206 KGELVVNDRIDREALCGQSASCVLTLQVVTENPLQLHRIEVEIKDINDNYPNFLTGERFL 1265
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-----VLSVNGE 1107
+ E+ A D D G N+ +Y + D ++ L+G L ++
Sbjct: 1266 KIAESTAAGVRFLLETAQDPDVGSNSVKSYTLS-KDECFSLKMKDLSGDRQIPELVLDKT 1324
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE +D + L + A D G D NDN P F
Sbjct: 1325 LDREKQDSHHLLLTAIDGG-NPVKTGTTTIIVTVLDNNDNVPVF 1367
Score = 39.1 bits (87), Expect = 0.92
Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 7/104 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P + T ++VTV D D V PVF Y + + EN + L+ + T+ E
Sbjct: 1343 GNPVKTGTTTIIVTVLDNNDNV-----PVFQKPLYNISLPENSSTSSVLLKVEATDADEG 1397
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
N ++ Y DI F +D G ++LV D E Y
Sbjct: 1398 VNGEIEYSFPEHTPQDILSVFRLDSSTGEIFLVGQLDYEKSIMY 1441
Score = 35.9 bits (79), Expect = 8.6
Identities = 47/225 (20%), Positives = 87/225 (38%), Gaps = 27/225 (12%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ E + +EV + D NDN P F+ + + + G A DPD+G
Sbjct: 1231 LQVVTENPLQLHRIEVEIKDINDNYPNFLTGERF-LKIAESTAAGVRFLLETAQDPDVGS 1289
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI-------LEGRHALFVEASDQPAN 544
N + Y L + ++ K+ +G + E + + H L + A D N
Sbjct: 1290 NSVKSYTLSKDECFSL----KMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAID-GGN 1344
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN 604
P + + +VT+ N ++P F Y + N + + ++ DA E
Sbjct: 1345 PVKTGTTTIIVTV------LDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADE-- 1396
Query: 605 DVSYDLLHGYEEGVP------FAVEERSGVITVVDDLSRYNRPMY 643
V+ ++ + + E P F ++ +G I +V L MY
Sbjct: 1397 GVNGEIEYSFPEHTPQDILSVFRLDSSTGEIFLVGQLDYEKSIMY 1441
Score = 35.9 bits (79), Expect = 8.6
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+PEN + ++K+ A D D G+NG+I Y F
Sbjct: 1376 LPENSSTSSVLLKVEATDADEGVNGEIEYSF 1406
>UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19;
Amniota|Rep: Protocadherin Fat 2 precursor - Homo sapiens
(Human)
Length = 4349
Score = 147 bits (356), Expect = 2e-33
Identities = 158/690 (22%), Positives = 299/690 (43%), Gaps = 42/690 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y I+G FS+D G + K +D + L + +V+
Sbjct: 480 VTATDRDHGENGYVTYS-IAGPKALPFSIDPYLGIISTSKPMD----YELMKRIYTFRVR 534
Query: 278 ASQLNNPLKTA-QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +P + + + ++L +LNDN P FE SI ++ P G S++ + A D D+
Sbjct: 535 ASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDEL 594
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-LDREAHSSLRMKVYAKETNPSVVGTFA 395
+N ++ + F ++ SG ++++ + L +S +K+ A + T
Sbjct: 595 QNLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPT-- 652
Query: 396 DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDN 455
+ I + E +KT V T I +++ ++ N
Sbjct: 653 -TLNITVVKDPHFEVPVTCDKTG-VLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHY 710
Query: 456 NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
P F + + + T + ++ A DPD G NG ++Y + + F I
Sbjct: 711 TPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNE---EGCFDIEL 767
Query: 516 NTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMG 575
TG ++VA E + + + + ++ S ++T+ V K + P F
Sbjct: 768 ETGLLTVAAPLDYEATNFYILNVTVYDLG-TPQKSSWKLLTVNV----KDWNDNAPRFPP 822
Query: 576 APYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGVITVVD 633
Y+ + + +GT++ ++ DA +++ V Y LL E+ F++ +G + V
Sbjct: 823 GGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEK---FSLHPLTGELVVTG 879
Query: 634 DLSRYNRPMYDFEAVALQENA---NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
L R + P Y + A + + L VT+ + + DVND + H+ + V E
Sbjct: 880 HLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCIT-EHNRL--KVPE 936
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
+ + + + G VR+++ + T + + G + ++ LD E+R
Sbjct: 937 DLPPGTVLTFLDASDPDL--GPAGEVRYVLMDGAHGTFRVDLM-TGALILERELDFERRA 993
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHATYEGFIMENSKIGTEIKM 808
Y +++ A ++ + V + + D N+N PP F ++G + ENS GT++
Sbjct: 994 GYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQV-- 1051
Query: 809 DNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
++ A D D G + Y L G G F ++++TG+++ + LDRE Y L+++A
Sbjct: 1052 -IVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLA-PLDREFASYYWLTVLA 1109
Query: 868 RDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
D G LSS E+ I + D NDN P+ +Q
Sbjct: 1110 VDRGSVPLSSVTEVYIEVTDANDNPPQMSQ 1139
Score = 130 bits (313), Expect = 4e-28
Identities = 130/474 (27%), Positives = 211/474 (44%), Gaps = 30/474 (6%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++F V++ L D NDN P F S Y S++SN + + +V A D D GQN V Y +
Sbjct: 2566 VAFCTVKIILTDENDNPPQFKASE-YTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSV 2624
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI-LEGRHA-LFVEASDQPANPSERRYSLAVVTI 557
+ +INP TG V V +S + LE + F++A D P SL V +
Sbjct: 2625 NPED--LVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQD--GGPPHWN-SLVPVRL 2679
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY--- 614
+V K +P F Y F ++ G+ +G ++ A Q+ V Y L+ G
Sbjct: 2680 QVVP----KKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAA--QDPVIYSLVRGTTPE 2733
Query: 615 --EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA-LQENANLSIVTNATVHVVDVND 671
++GV F+++ +GVI V + + +Y + +A +N ++ + + + V DVND
Sbjct: 2734 SNKDGV-FSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVND 2792
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQDVTDDI 730
R V + ++ + G ++ Q+ T + G +G + R +V +
Sbjct: 2793 NRPVFEADPYKAVL--TENMPVGTSVIQV--TAIDKDTGRDGQVSYRLSADPGSNVHELF 2848
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
AI +E G I T + LD E Y V+A + I + V + I DENDN P F
Sbjct: 2849 AIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFAS 2908
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
Y G ++ENS+ G + + A D E + Y G+ F + + +
Sbjct: 2909 EEYRGSVVENSEPGELVATLKTLDA-DISEQNRQVTCYITEGDPLGQFGISQVGDEWRIS 2967
Query: 850 G-DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+LDRE Y L + A D G + + I + D NDN P+ +Q+ KV
Sbjct: 2968 SRKTLDREHTAKYLLRVTASD-GKFQASVTVEIFVLDVNDNSPQCSQLLYTGKV 3020
Score = 125 bits (301), Expect = 1e-26
Identities = 128/460 (27%), Positives = 195/460 (42%), Gaps = 26/460 (5%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V + ++ + P F LY FS + G+ IG VKAV V+Y L
Sbjct: 2673 SLVPVRLQVVPKKVSLPKF-SEPLYTFSAPEDLPEGSEIGIVKAV----AAQDPVIYSLV 2727
Query: 501 R--TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
R T F ++P+TG + V + P+ L+ D A+ + +++V++
Sbjct: 2728 RGTTPESNKDGVFSLDPDTGVIKVRK-PMDHESTKLY--QIDVMAHCLQNTDVVSLVSVN 2784
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEE 616
+ G + P F PY+ + N+ +GTSV Q+ D VSY L
Sbjct: 2785 IQVGDVNDNR--PVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGS 2842
Query: 617 GVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
V FA++ SG IT + +L Y F VA + + + A V V + DE
Sbjct: 2843 NVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQV-SITDEND 2901
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA-IA 733
+ A V ENS + T + I ++ I+ +
Sbjct: 2902 NAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVG 2961
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++ I ++K LDRE Y + V A K S V I++ D NDN P Y
Sbjct: 2962 DEWRISSRKTLDREHTAKYLLRVTASDGKFQAS----VTVEIFVLDVNDNSPQCSQLLYT 3017
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
G + E+ G I + ATD D TNA Y+L G G F +D +TG + + +L
Sbjct: 3018 GKVHEDVFPGHFILK---VSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTL-TAL 3073
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
DRE+K ++ L A D GG S +A++ + + D NDN P F
Sbjct: 3074 DRERKDVFNLVAKATDGGGRSCQADITLHVEDVNDNAPRF 3113
Score = 119 bits (287), Expect = 5e-25
Identities = 149/580 (25%), Positives = 244/580 (42%), Gaps = 51/580 (8%)
Query: 589 GTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAV 648
G+ V +RV AF ++ Y +L E V F + R+G+IT + ++R Y
Sbjct: 378 GSRVVMVRVTPAFP--NLQY-VLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIR 434
Query: 649 ALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSS 707
A+ +V + +VD N+ + + ++ + EN G ++ + T+
Sbjct: 435 TSPGQASTVVV----IDIVDCNNHAPLFNRSSYDGTL---DENIPPGTSVLAVTATDRD- 486
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVIS 766
+G G V + IA + + I G I T KP+D E + +Y V A
Sbjct: 487 -HGEN-GYVTYSIAGPKALPFSID-PYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFR 543
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+ + + + NDN P+FE G I ++ +G I + A D DE N +
Sbjct: 544 REKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMT---MSAIDVDELQNLKYE 600
Query: 827 YTLFGEGKEMFDVDENTGVVKFIGD--SLDREKKIMYKLSLVARDTGGLSSEAEL-IIMI 883
+ G E FD++ +GV+ +L + Y L + A D +S L I ++
Sbjct: 601 I-VSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVV 659
Query: 884 GDENDNKP----EFNQIEENSKVRIH---RETKLNGTAGFTIIEVKPKNKFALDVDQLGP 936
D + P + + + +K +H + + + FT + N + + P
Sbjct: 660 KDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFP 719
Query: 937 LFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
+ + E++PI T + +L A D D+G NG++ Y + AD E + F I
Sbjct: 720 QSIDVLESVPINTPLARLAATDPDAGFNGKLVY------------VIADGNE-EGCFDIE 766
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYN 1051
G + VA L E+ + LN++ D G + + V VKD ND+ P F Y
Sbjct: 767 LETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQ 826
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
+ E + ++ DAD N + Y + S T+ F + PLTG L V G LDRE
Sbjct: 827 LTISEDTEVGTTIAELTTKDADSEDNGRVRYTLL-SPTE-KFSLHPLTGELVVTGHLDRE 884
Query: 1112 TEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPK 1150
+E +YIL V ARD DVNDNSP+
Sbjct: 885 SEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQ 924
Score = 111 bits (267), Expect = 1e-22
Identities = 130/487 (26%), Positives = 208/487 (42%), Gaps = 55/487 (11%)
Query: 431 NIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
N+ YD Q S+ + V + D NDN P F P Y+ ++ + +VGT I ++ D
Sbjct: 789 NVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGG-YQLTISEDTEVGTTIAELTTKDA 847
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANP 545
D NG V Y L L+ T F ++P TG + V E R+ L VEA DQP+
Sbjct: 848 DSEDNGRVRYTL-----LSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSK- 901
Query: 546 SERRYSLA--VVTIEVTRG------TKGNKPDIPDFM--GAPYEFWVGSNVGIGTSVGQI 595
+ +S+ ++T+E T+ N+ +P+ + G F S+ +G + G++
Sbjct: 902 GHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPA-GEV 960
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
R V D HG F V+ +G + + +L R Y+ A
Sbjct: 961 RY--------VLMDGAHG-----TFRVDLMTGALILERELDFERRAGYNLSLWASDGGRP 1007
Query: 656 LSIVTNATVHVV--DVNDERGVLLKGAHSPIIFH---VKENSAGAAIGQIFHTNMSSIYG 710
L+ T V V+ DVN+ L H H V+ENS Q+
Sbjct: 1008 LARRTLCHVEVIVLDVNEN----LHPPHFASFVHQGQVQENSPSGT--QVIVVAAQDDDS 1061
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
G +++ + + + G I T PLDRE Y +TV+A ++G + + +
Sbjct: 1062 GLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLA-VDRGSVPLSSV 1120
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL- 829
+V I + D NDNPP A + I E++ +GT + + A D D + + +
Sbjct: 1121 TEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQ---LDAWDPDSSSKGKLTFNIT 1177
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEN 887
G F + TG++ LDRE K + L + D G L S + +++ I D N
Sbjct: 1178 SGNYMGFFMIHPVTGLLS-TAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVN 1236
Query: 888 DNKPEFN 894
DN P F+
Sbjct: 1237 DNPPIFS 1243
Score = 109 bits (262), Expect = 6e-22
Identities = 134/477 (28%), Positives = 204/477 (42%), Gaps = 43/477 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + +AN +P F +LYE + NA VGT + + A+D D G G + Y +
Sbjct: 2465 VPVYINTTNANKYSPEF-QQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTI--- 2520
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
N + F INPN G ++ + E + + R +A T+++
Sbjct: 2521 INKLASEKFSINPN-GQIATLQKLDRENSTERVIAIKVMARDGGGR---VAFCTVKIILT 2576
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN-DVSYDLLHGYEEGVPF 620
+ + P P F + Y + SNV + V Q+ DA E QN DV+Y + E+ V
Sbjct: 2577 DENDNP--PQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSV--NPEDLVKD 2632
Query: 621 AVEER--SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLL 677
+E +GV+ V D L DF + Q+ N+ V V + V ++ L
Sbjct: 2633 VIEINPVTGVVKVKDSLVGLENQTLDF-FIKAQDGGPPH--WNSLVPVRLQVVPKKVSLP 2689
Query: 678 KGAHSPIIFHVKEN-SAGAAIGQIFHTNMSS--IYGNGTGNVRFLIANQQDVTDDIAIAE 734
K + F E+ G+ IG + IY G +N+ V +
Sbjct: 2690 KFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTP--ESNKDGVFS--LDPD 2745
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEF--NKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G I +KP+D E +Y++ V+A N V+S + V I + D NDN PVFE Y
Sbjct: 2746 TGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVS---LVSVNIQVGDVNDNRPVFEADPY 2802
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKF 848
+ + EN +GT + + A D D G + Y L + E+F +D +G +
Sbjct: 2803 KAVLTENMPVGTSVIQ---VTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITT 2859
Query: 849 IGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ LD E Y +VA D G LSS+A + + I DENDN P F E V
Sbjct: 2860 L-QELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSV 2915
Score = 105 bits (251), Expect = 1e-20
Identities = 118/463 (25%), Positives = 206/463 (44%), Gaps = 42/463 (9%)
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
+ + N + P F+ + YE + + G + +V+A+D D G++ ++Y + + +
Sbjct: 1438 IANINHHRPQFLETR-YEVRVPQDTVPGVELLRVQAIDQDKGKS--LIYTIHGSQDPGSA 1494
Query: 509 SPFKINPNTGT-VSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
S F+++P++G V+V + + G +H L V DQ P +R + VTI V G
Sbjct: 1495 SLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEI-PIKRNF--VWVTIHVEDGNL- 1550
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVE 623
P P F YE V + GT + Q+R DA +V Y LL G EG F +
Sbjct: 1551 -HP--PRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGF-FNIN 1606
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHS 682
G+IT+ L + N + A + + + +HV + + K S
Sbjct: 1607 ALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSK---S 1663
Query: 683 PIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ E+ G+ I + + S + T +R N+ V + + G I TQ
Sbjct: 1664 EYFVEIPESIPVGSPILLVSAMSPSEV----TYELRE--GNKDGVFSMNSYS--GLISTQ 1715
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
K LD EK Y++ + G + V + I DENDN P+F +T+ G I E +
Sbjct: 1716 KKLDHEKISSYQLKIRGSNMAGAFTDV---MVVVDIIDENDNAPMFLKSTFVGQISEAAP 1772
Query: 802 IGTEIKMDN----IIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDRE 856
+ + I N +I A+D+D+ N+L +Y + E + F +D + G + + + +D E
Sbjct: 1773 LYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSE-MDYE 1831
Query: 857 KKIMYKLSLVARDTGG----LSSEAELIIMIGDENDNKPEFNQ 895
++ + D G A++II + D ND+ P F++
Sbjct: 1832 SMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSE 1874
Score = 102 bits (244), Expect = 9e-20
Identities = 116/454 (25%), Positives = 191/454 (42%), Gaps = 30/454 (6%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN P F PS+ ++ N V T + V A DPD G N V+Y L ++
Sbjct: 3105 DVNDNAPRFFPSHC-AVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAE----GH 3159
Query: 511 FKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F I+ TG + + E P+ A L V ASD P +L VT+ V G +
Sbjct: 3160 FSIDATTGVIRL-EKPLQVRPQAPLELTVRASDL-GTPIPLS-TLGTVTVSVV----GLE 3212
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
+P F+ + V + GT V Q+ Y ++ G E+G F ++ R+G
Sbjct: 3213 DYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNEQG-RFRLDARTG 3271
Query: 628 VITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
++ V L P Y + + +++LS VT V++ DVN+ R + +S
Sbjct: 3272 ILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYST--- 3328
Query: 687 HVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
V EN A +G + T + + G ++ + + + + G + K LD
Sbjct: 3329 RVLEN---ALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALD 3385
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE+ Y + + A + G + I + D NDNPP F Y + ENS IG++
Sbjct: 3386 REQASSYSLKLRAT-DSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSK 3444
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ + I+ D+ E G F V + +V + L R + Y+L +
Sbjct: 3445 V-LQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLV--TAEGLSRRAQEWYQLQI 3501
Query: 866 VARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
A D+G LSS + + + +++ P +E
Sbjct: 3502 QASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLE 3535
Score = 99 bits (238), Expect = 5e-19
Identities = 142/588 (24%), Positives = 241/588 (40%), Gaps = 49/588 (8%)
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+++QV TD++ +N + ++ +G+ + G L +T+ + + ++ Y
Sbjct: 2890 ALVQVSITDEN--DNAP-RFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYI 2946
Query: 384 KETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFV 443
E +P +G F SQ +WR +T Y+ + D + + V
Sbjct: 2947 TEGDP--LGQFGISQVGDEWRISSRKTLDREHTAKYLL---------RVTASDGKFQASV 2995
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
VE+ +LD NDN+P LY + + G I KV A D D N + Y L
Sbjct: 2996 TVEIFVLDVNDNSPQ-CSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPG 3054
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
FK++P+TG ++ + E + + A A R A +T+ V
Sbjct: 3055 ----AHEFKLDPHTGELTTLTALDRERKDVFNLVAK---ATDGGGRSCQADITLHV---- 3103
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFA 621
+ + P F + V N + T V + D + V Y L E F+
Sbjct: 3104 EDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGH--FS 3161
Query: 622 VEERSGVITVVDDLS-RYNRPM-YDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
++ +GVI + L R P+ A L LS + TV VV + D V L
Sbjct: 3162 IDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNT 3221
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
HS + ++ G + Q+ ++ TG R + N+Q A G ++
Sbjct: 3222 EHSVQV--PEDAPPGTEVLQL--ATLTRPGAEKTG-YRVVSGNEQGRFR--LDARTGILY 3274
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
LD E Y +++ K S + + V + I D N++ P F Y ++EN
Sbjct: 3275 VNASLDFETSPKYFLSIECS-RKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLEN 3333
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--FDVDENTGVVKFIGDSLDREK 857
+ +G I + ATD D N+ Y+L G G ++ F + G ++ + +LDRE+
Sbjct: 3334 ALVGDVILT---VSATDEDGPLNSDITYSLIG-GNQLGHFTIHPKKGELQ-VAKALDREQ 3388
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
Y L L A D+G L + ++ I + D NDN P F Q+ ++ V+
Sbjct: 3389 ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQ 3436
Score = 91.9 bits (218), Expect = 1e-16
Identities = 104/473 (21%), Positives = 203/473 (42%), Gaps = 34/473 (7%)
Query: 444 NVEVTLLDANDN-NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+VEV +LD N+N +P S +++ ++ N+ GT + V A D D G +G + Y L+
Sbjct: 1015 HVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAG 1074
Query: 503 SNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ L + F IN +TG + +P+ + L V A D+ + P S+ V IEV
Sbjct: 1075 TGL---AAFSINQDTGMIQTL-APLDREFASYYWLTVLAVDRGSVPLS---SVTEVYIEV 1127
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
T N P + + P + + +GTSV Q+ D+ + +++++ G G
Sbjct: 1128 T-DANDNPPQMSQAVFYPS---IQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMG 1183
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F + +G+++ L R N+ + E L +L + V ++DVND +
Sbjct: 1184 F-FMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIF 1242
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+H + E + + G ++ S + G V + I + + I + G
Sbjct: 1243 ---SHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSYEEAFSIDLVT-G 1298
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ + + ++ + + + ++ I + P F+ Y +
Sbjct: 1299 VVSSNSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTV 1358
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDR 855
ME + + + ++ EG LF + + G K+M FD+++ TG + I LD
Sbjct: 1359 METDPVNHMVGVISV-------EGRPGLFWFNISGGDKDMDFDIEKTTGSI-VIARPLDT 1410
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
++ Y L++ D + I MI + N ++P+F +E +VR+ ++T
Sbjct: 1411 RRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQF--LETRYEVRVPQDT 1461
Score = 91.9 bits (218), Expect = 1e-16
Identities = 112/478 (23%), Positives = 192/478 (40%), Gaps = 41/478 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
++S V+V + + D NDN PVF ++ Y+ + N VGT + +V A+D D G++G V Y
Sbjct: 2777 VVSLVSVNIQVGDVNDNRPVF-EADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYR 2835
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + F I+ +G ++ + E + + S A+V +
Sbjct: 2836 LSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVS 2895
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+T + P F Y V N G V ++ DA + ++ + + EG
Sbjct: 2896 IT----DENDNAPRFASEEYRGSVVENSEPGELVATLKTLDA-DISEQNRQVTCYITEGD 2950
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVA------LQENANLSIVTNATVHVVDVNDE 672
P + G+ V D+ +R D E A + + V+DVND
Sbjct: 2951 PLG---QFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVLDVNDN 3007
Query: 673 ----RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQDVT 727
+L G +F +A TN Y +G G F +
Sbjct: 3008 SPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLD------ 3061
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G + T LDRE++DV+ + A G A +T+++ED NDN P F
Sbjct: 3062 -----PHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQA---DITLHVEDVNDNAPRF 3113
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ + +N+ + T + ++ A D D+G NA +Y+L + F +D TGV++
Sbjct: 3114 FPSHCAVAVFDNTTVKTPVA---VVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIR 3170
Query: 848 FIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ L + +L++ A D G LS+ + + + D P F E + +V
Sbjct: 3171 -LEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQV 3227
Score = 88.6 bits (210), Expect = 1e-15
Identities = 154/676 (22%), Positives = 256/676 (37%), Gaps = 63/676 (9%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G I T K +D R Y++ + G V I I D N++ P+F ++Y
Sbjct: 410 ARTGLITTTKLMDFHDRAHYQLHIRTS------PGQASTVVVIDIVDCNNHAPLFNRSSY 463
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+G + EN GT + + ATD D G N Y++ G F +D G++
Sbjct: 464 DGTLDENIPPGTSVLA---VTATDRDHGENGYVTYSIAGPKALPFSIDPYLGIIS-TSKP 519
Query: 853 LDRE-KKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
+D E K +Y + A D G E + + + + NDN+P F ++ +R
Sbjct: 520 MDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPV 579
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
+ I+V ++ L N G +K ++L +G Y
Sbjct: 580 G-KSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQ--PTSY 636
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS----LPPESEFRLNISALDGGN 1024
+ S L + V+ + H V V L ++ L+ L
Sbjct: 637 SLKITASDGKNYASPTTLNIT---VVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQE 693
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTW-YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+D + +N + P F+ + + +V E+ L ++ ATD D G N L Y
Sbjct: 694 SSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYV 753
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
I + + F+I TG+L+V LD E + YIL V D G D
Sbjct: 754 IADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLG-TPQKSSWKLLTVNVKD 812
Query: 1144 VNDNSPKF----YAF---------DELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
NDN+P+F Y + E +AD N ++ P K ++
Sbjct: 813 WNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLH--- 869
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
P+ T V D ++ + ++Q + G L S L++T+ DV D
Sbjct: 870 PL--TGELVVTGHLDRESEPRYILKV---EARDQPSKG-HQLFSVTDLIITLEDVND--- 920
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVI 1308
+ P I+ + L++ E++ L L+ ++ ++RY +++ TF +
Sbjct: 921 --NSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMD----GAHGTFRV 974
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIVRAE---RQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
D G L L R D E + Y + + A R R L H + + DV E +
Sbjct: 975 DLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCH-VEVIVLDVNENLHPPHFA 1033
Query: 1366 VVVRIKDVNDNSPKFT 1381
V V +NSP T
Sbjct: 1034 SFVHQGQVQENSPSGT 1049
Score = 84.6 bits (200), Expect = 2e-14
Identities = 87/338 (25%), Positives = 145/338 (42%), Gaps = 23/338 (6%)
Query: 1011 SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+++ L ++A DG +++V +FV DVND+ P + Y V E + + KV AT
Sbjct: 2978 AKYLLRVTASDG-KFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSAT 3036
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D NA +TY + F++ P TG L+ LDRE +D + L A D G
Sbjct: 3037 DLDTDTNAQITYSLHGPGAH-EFKLDPHTGELTTLTALDRERKDVFNLVAKATDGG---G 3092
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
DVNDN+P+F+ H N ++ + + V+ ++ A
Sbjct: 3093 RSCQADITLHVEDVNDNAPRFFP-------SHCAVAVFDNTTVKTPVAV-VFARDPDQGA 3144
Query: 1191 PIGTTVAKVFANDTDF-IGNGNGLILYSLP-QRKNQQNLGLPSLSS---TAILMVTVADV 1245
+ + + F I G+I P Q + Q L L +S T I + T+ V
Sbjct: 3145 NAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTV 3204
Query: 1246 P-DEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIR 1303
V + D PVF++ + +++ E+ E++ L K Y +++ N+ +
Sbjct: 3205 TVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNE---Q 3261
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
F +D R G LY+ S D E Y + + R+ S
Sbjct: 3262 GRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSS 3299
Score = 82.6 bits (195), Expect = 8e-14
Identities = 55/173 (31%), Positives = 85/173 (49%), Gaps = 12/173 (6%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
QD + + +R N +FSLD G + + K +D ++ + + V A L
Sbjct: 2719 QDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHES-----TKLYQIDVMAHCLQ 2773
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
N + V I++ D+NDN P FE D Y + EN+P G SV+QV A DKD G +G+ +
Sbjct: 2774 NTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVS 2833
Query: 343 YQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
Y+L G+ F+ID SGW+T + LD E + V A + ++
Sbjct: 2834 YRLSADPGSNVHELFAIDSESGWITTLQE--LDCETCQTYHFHVVAYDHGQTI 2884
Score = 81.4 bits (192), Expect = 2e-13
Identities = 123/506 (24%), Positives = 209/506 (41%), Gaps = 49/506 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V++ D NDN P F Y ++ + G V+ +V A D DLG NG V Y+
Sbjct: 2056 VRVSIEDVNDNPPKFKHLPYYTI-IQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYT 2114
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F+I+P G +S+ + + ++ L V A D PS + +VT+
Sbjct: 2115 Y-----FRIDPYLGDISLKKPFDYQALNKYHLKVIARD-GGTPSLQSEEEVLVTVR---- 2164
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
K N P F Y+ V N+ + T + + E + Y+++ E + F
Sbjct: 2165 NKSN----PLFQSPYYKVRVPENITLYTPILHTQARSP-EGLRLIYNIVE-EEPLMLFTT 2218
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGA 680
+ ++GV+TV L ++ + F A + L + ATV V+ DVND +
Sbjct: 2219 DFKTGVLTVTGPLDYESKTKHVFTVRA--TDTALGSFSEATVEVLVEDVNDNPPTFSQLV 2276
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIF 739
++ I + A + Q+ ++ S G ++ + DV+ I G +
Sbjct: 2277 YTTSI--SEGLPAQTPVIQLLASDQDS--GRNRDVSYQIVEDGSDVSKFFQINGSTGEMS 2332
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T + LD E + + + V A +KG G V + + D NDNPP F YE + E
Sbjct: 2333 TVQELDYEAQQHFHVKVRA-MDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSEL 2391
Query: 800 SKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ G + ++A D D T+ L L G F ++ ++G++ + +
Sbjct: 2392 ATCGHLVLK---VQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMF-NLCKKHLD 2447
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ------IEENSKV--------RI 904
Y L + A D G + + I + N PEF Q + EN+ V I
Sbjct: 2448 SSYNLRVGASD-GVFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAI 2506
Query: 905 HRETKLNGTAGFTIIEVKPKNKFALD 930
+++ GT +TII KF+++
Sbjct: 2507 DKDSGPYGTIDYTIINKLASEKFSIN 2532
Score = 81.4 bits (192), Expect = 2e-13
Identities = 95/398 (23%), Positives = 160/398 (40%), Gaps = 26/398 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTI 140
V V IEDVNDN P F PY+ + + T G+ F +G + + T
Sbjct: 2056 VRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTY 2115
Query: 141 FKD---IRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
F+ + KP + Y + V D G +L+S + ++ +R + +
Sbjct: 2116 FRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVR-----NKSNPL 2170
Query: 197 FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
FQ R+ + I PI G L Y ++ LF+ D G L +
Sbjct: 2171 FQSPYYKV--RVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVT 2228
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV 316
LD +++ + F ++ + L + ++A VE+ + D+NDN P F Y SI
Sbjct: 2229 GPLDYESKTK---HVFTVRATDTALGS---FSEATVEVLVEDVNDNPPTFSQLVYTTSIS 2282
Query: 317 ENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
E LP V+Q++A+D+D G N + +YQ+ D F I+ +G ++ + LD E
Sbjct: 2283 EGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQE--LDYE 2340
Query: 373 AHSSLRMKVYAKET-NPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTEN 431
A +KV A + +P + G ++ P E P + G
Sbjct: 2341 AQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLK 2400
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSM 469
++ D +E +L N + F+ S+ SM
Sbjct: 2401 VQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISM 2438
Score = 80.2 bits (189), Expect = 4e-13
Identities = 67/216 (31%), Positives = 102/216 (47%), Gaps = 18/216 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT +I + A D DSGL+G+++Y + + L+A F IN+ G
Sbjct: 1041 VQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAG-----TGLAA--------FSINQDTG 1087
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L E S + L + A+D G+ L+ V + V D ND+ P + + +++
Sbjct: 1088 MIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQ 1147
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + ++DA D D LT+ I + F I P+TG+LS +LDRE +D+
Sbjct: 1148 EDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDE 1207
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+IL V DNG DVNDN P F
Sbjct: 1208 HILEVTVLDNG-EPSLKSTSRVVVGILDVNDNPPIF 1242
Score = 78.6 bits (185), Expect = 1e-12
Identities = 66/221 (29%), Positives = 100/221 (45%), Gaps = 24/221 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD-ALEVKRYFVINER 997
++ EN+P+GT++I++ A+D D+G +GQ+ Y +LSAD V F I+
Sbjct: 2805 VLTENMPVGTSVIQVTAIDKDTGRDGQVSY-----------RLSADPGSNVHELFAIDSE 2853
Query: 998 HGHVIVARSLPPES--EFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
G + + L E+ + ++ A D G L+ V+V + D ND+ P F Y
Sbjct: 2854 SGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRG 2913
Query: 1053 NVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDTDLPFEISPLTGV--LSVNGELD 1109
+V E ++ + DAD QN +T +I D F IS + +S LD
Sbjct: 2914 SVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLD 2973
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
RE KY+L V A D DVNDNSP+
Sbjct: 2974 REHTAKYLLRVTASDG----KFQASVTVEIFVLDVNDNSPQ 3010
Score = 78.2 bits (184), Expect = 2e-12
Identities = 122/502 (24%), Positives = 206/502 (41%), Gaps = 66/502 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +P T +I+L A D DSG N + Y+ + D +V ++F IN G
Sbjct: 2281 ISEGLPAQTPVIQLLASDQDSGRNRDVSYQ-----------IVEDGSDVSKFFQINGSTG 2329
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + L E++ F + + A+D G+ L V V V D+ND+ P F++ Y NV
Sbjct: 2330 EMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVS 2389
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E ++ KV A D D + L Y I + D F I+ +G++S+ + +
Sbjct: 2390 ELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSS 2449
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y L V A D + N SP+F +H EL+ +
Sbjct: 2450 YNLRVGASDG----VFRATVPVYINTTNANKYSPEFQ--------QHLYEAELAENAMVG 2497
Query: 1176 VMMIPVYKATIEENAPIGT---TVAKVFANDTDFIG-NGNGLILYSLPQRKNQQN-LGLP 1230
+I + A +++ P GT T+ A++ I NG L L + + + + +
Sbjct: 2498 TKVIDLL-AIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQKLDRENSTERVIAIK 2556
Query: 1231 SLSSTA---ILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHY 1285
++ + TV + + E + P F + Y + I+ NV ++PV V +
Sbjct: 2557 VMARDGGGRVAFCTVKIILTD-ENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEG 2615
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+N + Y + N D ++ I+P G + +VKD+ +V E Q
Sbjct: 2616 QNADVTYSV-NPEDL-VKDVIEINPVTGVV--------KVKDS---LVGLENQTLD---- 2658
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDV--NDNSPKFTNGNRPLVT-AIPTTAPFGYQVM 1402
+ A+D G ++ V VR++ V + PKF + PL T + P P G ++
Sbjct: 2659 --FFIKAQD--GGPPHWNSLVPVRLQVVPKKVSLPKF---SEPLYTFSAPEDLPEGSEIG 2711
Query: 1403 QLKGAIGHHPTASRTVRADTDE 1424
+K P VR T E
Sbjct: 2712 IVKAVAAQDPVIYSLVRGTTPE 2733
Score = 77.8 bits (183), Expect = 2e-12
Identities = 48/156 (30%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y ++SGN++ F LD+ G L++ LD + + L ++ S+ ++ + V
Sbjct: 3253 YRVVSGNEQGRFRLDARTGILYVNASLDFETSPK-----YFLSIECSRKSSSSLSDVTTV 3307
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKG 350
+ + D+N++ P+F D Y+ ++EN G +L V ATD+D N + TY L + G
Sbjct: 3308 MVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLG 3367
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
F+I P+ G L V LDRE SS +K+ A ++
Sbjct: 3368 HFTIHPKKGELQVAK--ALDREQASSYSLKLRATDS 3401
Score = 77.0 bits (181), Expect = 4e-12
Identities = 84/323 (26%), Positives = 141/323 (43%), Gaps = 27/323 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S +VTV + + D +P+FL+T + V V E P G + + +A +LT P
Sbjct: 3198 LSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTE--VLQLA----TLTRPGAEKT 3251
Query: 137 GLTIFK-DIRAFDRDKPNTPNSDVHYSIVSGNDDGHF-ALESSHKPVLLLRKVLDY---- 190
G + + + R T V+ S+ +F ++E S K L V
Sbjct: 3252 GYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNI 3311
Query: 191 -DAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLFSL 246
D + Q R+ + L + I A D+D + + + Y LI GN F++
Sbjct: 3312 TDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTI 3371
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G L + K LD + QA+++ L+++A+ P + I++ D+NDN P F
Sbjct: 3372 HPKKGELQVAKALDRE-----QASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRF 3426
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENG---EFTYQLDDPKGAFSIDPRSGWLTV 363
Y+ ++ EN P G VLQ++ +D D ENG F + AF + P GWL
Sbjct: 3427 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVT 3485
Query: 364 RNQTVLDREAHSSLRMKVYAKET 386
L R A ++++ A ++
Sbjct: 3486 AEG--LSRRAQEWYQLQIQASDS 3506
Score = 74.5 bits (175), Expect = 2e-11
Identities = 107/473 (22%), Positives = 194/473 (41%), Gaps = 35/473 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL S V+V++ D NDN P F S Y S+ N++ G ++ +K +D D+ +
Sbjct: 2885 QLSSQALVQVSITDENDNAPRFA-SEEYRGSVVENSEPGELVATLKTLDADISEQ----- 2938
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQ---PANPSERRYSLAV 554
+ Q T +T P G V + + R L E + + S+ ++ A
Sbjct: 2939 NRQVTCYITEGDPL---GQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQ-AS 2994
Query: 555 VTIEV-TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
VT+E+ N P + Y V +V G + ++ D + ++Y L
Sbjct: 2995 VTVEIFVLDVNDNSPQCSQLL---YTGKVHEDVFPGHFILKVSATDLDTDTNAQITYS-L 3050
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
HG F ++ +G +T + L R + +++ A A + S + T+HV DVND
Sbjct: 3051 HG-PGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKA-TDGGGRSCQADITLHVEDVND 3108
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ +F + + +F + V + + + + I
Sbjct: 3109 NAPRFFPSHCAVAVF--DNTTVKTPVAVVFARDPDQ---GANAQVVYSLPDSAEGHFSID 3163
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A G I +KPL + +TV A I + + VT+ + D PVF +
Sbjct: 3164 -ATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTE 3222
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ + E++ GTE+ + AT G + G + F +D TG++ ++
Sbjct: 3223 HSVQVPEDAPPGTEV----LQLATLTRPGAEKTGYRVVSGNEQGRFRLDARTGIL-YVNA 3277
Query: 852 SLDREKKIMYKLSLVA--RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
SLD E Y LS+ + + LS +++ I D N+++P+F Q +++V
Sbjct: 3278 SLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRV 3330
Score = 74.1 bits (174), Expect = 3e-11
Identities = 109/465 (23%), Positives = 194/465 (41%), Gaps = 41/465 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+FV V + + D N + P F + YE S+ GT + +V+A+D D G N V Y L
Sbjct: 1537 NFVWVTIHVEDGNLHPPRFTQLH-YEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLL 1595
Query: 501 RTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ ++ F IN G +++A+ H L V+A DQ S + + LA V I
Sbjct: 1596 KGNS---EGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQ---GSPQWHDLATVIIH 1649
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V + P F + Y + ++ +G+ I + A ++V+Y+L G ++GV
Sbjct: 1650 VYPSDR----SAPIFSKSEYFVEIPESIPVGS---PILLVSAMSPSEVTYELREGNKDGV 1702
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F++ SG+I+ L Y + + A V ++D ND + LK
Sbjct: 1703 -FSMNSYSGLISTQKKLDHEKISSYQLK-IRGSNMAGAFTDVMVVVDIIDENDNAPMFLK 1760
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-----VRFLIANQQDVTDDIAIA 733
S + + E + ++ + N I+ + + + + I + +
Sbjct: 1761 ---STFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDP 1817
Query: 734 EDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
GT+ +D E ++ V + + V+ QV I++ D ND+PP F Y
Sbjct: 1818 SMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIY 1877
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGD 851
E I+ G E+ M ++A+D D N Y++ G E + TG + +
Sbjct: 1878 EVAIVGPIHPGMELLM---VRASDEDSEVN----YSIKTGNADEAVTIHPVTGSISVLNP 1930
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELI-IMIGDENDNKPEFNQ 895
+ + KL++ A D GL + L+ I + D +F+Q
Sbjct: 1931 AF---LGLSRKLTIRASD--GLYQDTALVKISLTQVLDKSLQFDQ 1970
Score = 73.7 bits (173), Expect = 3e-11
Identities = 100/397 (25%), Positives = 165/397 (41%), Gaps = 43/397 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ P+GT++++L+A D DS G++ + S Y+ +F+I+ G
Sbjct: 1146 IQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMG-------------FFMIHPVTG 1192
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A+ L E+ E L ++ LD G +L V V + DVND+ P+F +N +
Sbjct: 1193 LLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLP 1252
Query: 1056 E--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + + + ++ A+D D G N +TY I+ S + F I +TGV+S N T
Sbjct: 1253 ERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSYEE-AFSIDLVTGVVSSNSTF---TA 1308
Query: 1114 DKY-ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE-LLEWKHPEADELSNH 1171
+Y ILT+ A D+G +S AFDE + E D + NH
Sbjct: 1309 GEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPL-AFDETYYSFTVMETDPV-NH 1366
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---IGNGNGLILYSLP---QRKNQQ 1225
M+ V E P G + D D I G I+ + P +R++
Sbjct: 1367 ------MVGVISV---EGRP-GLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNY 1416
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
NL + + + V +P F+ YE+ + ++ VEL+ + +
Sbjct: 1417 NLTVEVTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQD 1476
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+ + Y I D F +DP +G L V D
Sbjct: 1477 KGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLD 1513
Score = 73.7 bits (173), Expect = 3e-11
Identities = 111/468 (23%), Positives = 199/468 (42%), Gaps = 52/468 (11%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM-VLYDLQRTSN 504
EV + N +NP+F S Y+ + N + T I +A P+ G+ ++Y++
Sbjct: 2158 EVLVTVRNKSNPLF-QSPYYKVRVPENITLYTPILHTQARSPE----GLRLIYNIVEEEP 2212
Query: 505 LTI-TSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
L + T+ FK TG ++V E + H V A+D S + T+EV
Sbjct: 2213 LMLFTTDFK----TGVLTVTGPLDYESKTKHVFTVRATDTALG------SFSEATVEVLV 2262
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLH-GYEEGV 618
+ P P F Y + + T V Q+ +D + DVSY ++ G +
Sbjct: 2263 EDVNDNP--PTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSK 2320
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLL 677
F + +G ++ V +L + + + A+ + + L+ T V+V D+ND
Sbjct: 2321 FFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFR 2380
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI-ANQQDVTDDIAIAEDG 736
+ + + + + G + ++ + S T + +LI + QD I
Sbjct: 2381 QPQYEANVSELA--TCGHLVLKVQAIDPDS---RDTSRLEYLILSGNQD--RHFFINSSS 2433
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI--YIEDENDNP--PVFEHATY 792
I + L ++ D + +N V + G+++ T+ YI N N P F+ Y
Sbjct: 2434 GIISMFNLCKKHLD-------SSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLY 2486
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGD 851
E + EN+ +GT++ +D + A D D G YT+ + E F ++ N +
Sbjct: 2487 EAELAENAMVGTKV-ID--LLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATL--Q 2541
Query: 852 SLDREKKI--MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
LDRE + + ++ARD GG + + I++ DENDN P+F E
Sbjct: 2542 KLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASE 2589
Score = 72.5 bits (170), Expect = 8e-11
Identities = 166/726 (22%), Positives = 288/726 (39%), Gaps = 97/726 (13%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + DANDN P + Y S++ +A VGT + ++ A DPD G + ++
Sbjct: 1117 LSSVTEVYIEVTDANDNPPQMSQAVFYP-SIQEDAPVGTSVLQLDAWDPDSSSKGKLTFN 1175
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + + F I+P TG +S A+ E + H L V D PS + S VV
Sbjct: 1176 ITSGNYMGF---FMIHPVTGLLSTAQQLDRENKDEHILEVTVLDN-GEPSLKSTSRVVVG 1231
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
I N P + S V G V ++ +D E V+Y + Y
Sbjct: 1232 I---LDVNDNPPIFSHKLFNVRLPERLSPVSPGP-VYRLVASDLDEGLNGRVTYSIEDSY 1287
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER- 673
EE F+++ +GV++ S + Y+ + ++ + + +H+ + R
Sbjct: 1288 EEA--FSIDLVTGVVS---SNSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRP 1342
Query: 674 -GVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDDI 730
+ L + F V E +G I S+ G G F I+ +D+ DI
Sbjct: 1343 SSIPLAFDETYYSFTVMETDPVNHMVGVI------SVEGR-PGLFWFNISGGDKDMDFDI 1395
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY-IEDENDNPPVFEH 789
G+I +PLD +R Y +TV E G S QV I+ I + N + P F
Sbjct: 1396 E-KTTGSIVIARPLDTRRRSNYNLTV--EVTDG--SRTIATQVHIFMIANINHHRPQFLE 1450
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
YE + +++ G E+ ++A D D+G + + YT+ G ++ G
Sbjct: 1451 TRYEVRVPQDTVPGVELLR---VQAIDQDKGKSLI--YTIHGS--------QDPGSASLF 1497
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LD ++ + + D G S+ L +M+ D+ E
Sbjct: 1498 --QLDPSSGVLVTVGKL--DLGSGPSQHTLTVMVRDQ--------------------EIP 1533
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
+ + I V+ N QL +P+ I GT ++++ A+D D G+N ++ Y
Sbjct: 1534 IKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHY- 1592
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP--ESEFRLNISALDGGN--L 1025
S L ++ + +F IN G + +A+ L + L + A D G+
Sbjct: 1593 ---------SLLKGNS---EGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQW 1640
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
+D +V + V + P+F K+ Y + E+ + V A + +TY ++
Sbjct: 1641 HDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSP-----SEVTYELR 1695
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ D F ++ +G++S +LD E Y L + D N
Sbjct: 1696 EGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKI---RGSNMAGAFTDVMVVVDIIDEN 1752
Query: 1146 DNSPKF 1151
DN+P F
Sbjct: 1753 DNAPMF 1758
Score = 72.1 bits (169), Expect = 1e-10
Identities = 78/302 (25%), Positives = 127/302 (42%), Gaps = 32/302 (10%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS---------LTIPLT 133
V V + D+NDN P F Y V EL G + + I P L +
Sbjct: 2365 VVVNVSDINDNPPEFRQPQYEANVSELATCGH--LVLKVQAIDPDSRDTSRLEYLILSGN 2422
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
R I + D Y++ G DG F + PV + + +
Sbjct: 2423 QDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFR---ATVPVYI--NTTNANKY 2477
Query: 194 DKEFQLVI----MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
EFQ + +A + +++ + AID+D G T+ Y +I+ + FS++
Sbjct: 2478 SPEFQQHLYEAELAENAMVGTKVI---DLLAIDKDSGPYGTIDYTIINKLASEKFSINP- 2533
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
NG + ++LD + N ++V A + A V+I L D NDN P+F+
Sbjct: 2534 NGQIATLQKLDRE---NSTERVIAIKVMARDGGG--RVAFCTVKIILTDENDNPPQFKAS 2588
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQ 366
Y +SI N+ V+QV+A D D+G+N + TY + D K I+P +G + V++
Sbjct: 2589 EYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDS 2648
Query: 367 TV 368
V
Sbjct: 2649 LV 2650
Score = 71.7 bits (168), Expect = 1e-10
Identities = 110/473 (23%), Positives = 193/473 (40%), Gaps = 38/473 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPS--NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
+ L S V V +LD NDN P+F N+ S G V ++ A D D G NG
Sbjct: 1219 EPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVY-RLVASDLDEGLNG 1277
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH-ALFVEASDQPANPSERRYSL 552
V Y ++ + F I+ TG VS + S G + L ++A+D P L
Sbjct: 1278 RVTYSIEDSYE----EAFSIDLVTGVVS-SNSTFTAGEYNILTIKATDSGQPPLSASVRL 1332
Query: 553 AVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
+ I R + IP F Y F V + VG I V + + + +
Sbjct: 1333 HIEWIPWPRPSS-----IPLAFDETYYSFTVMETDPVNHMVGVISVEG---RPGLFWFNI 1384
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV-DVN 670
G ++ + F +E+ +G I + L R Y+ V + + + +I T + ++ ++N
Sbjct: 1385 SGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNL-TVEVTDGSR-TIATQVHIFMIANIN 1442
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
R L+ + + ++ G + ++ +I + ++ + I QD
Sbjct: 1443 HHRPQFLETRYEVRV--PQDTVPGVELLRV-----QAIDQDKGKSLIYTIHGSQDPGSAS 1495
Query: 731 AIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
D G + T LD + ++ + VTI++ED N +PP F
Sbjct: 1496 LFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRF 1555
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVV 846
YE + + GTE+ ++A DAD G NA Y+L G + F+++ G++
Sbjct: 1556 TQLHYEASVPDTIAPGTELLQ---VRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGII 1612
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
+ LD+ + L++ A D G A +II + + + P F++ E
Sbjct: 1613 T-LAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSE 1664
Score = 71.3 bits (167), Expect = 2e-10
Identities = 92/357 (25%), Positives = 140/357 (39%), Gaps = 40/357 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
VRV ++DVND+ P FK Y +++ VL +V ATD D G N +TY T
Sbjct: 2056 VRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYT- 2114
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I P G +S+ D + +KY L V+ARD G N ++P
Sbjct: 2115 -YFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVR---NKSNPL 2170
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIP-----VYKATIEENAPIGTTVAKVFANDTD 1205
F + + + PE L + P +Y EE + TT K
Sbjct: 2171 FQS--PYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVT 2228
Query: 1206 FIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+ + R LG S ++ +L+ V D P P F Y
Sbjct: 2229 GPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNP--------PTFSQLVYTTS 2280
Query: 1266 IEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
I E + A ++ L ++ N + Y I+ E+ +D+ + F I+ G + V+ D
Sbjct: 2281 ISEGLPAQTPVIQLLASDQDSGRNRDVSYQIV-EDGSDVSKFFQINGSTGEMSTVQELDY 2339
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
E + + V VRA + + L G T VVV + D+NDN P+F
Sbjct: 2340 EAQQHFHVKVRAMDK-------------GDPPLTGET----LVVVNVSDINDNPPEF 2379
Score = 70.1 bits (164), Expect = 4e-10
Identities = 66/223 (29%), Positives = 98/223 (43%), Gaps = 31/223 (13%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNI--SALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F ++ R G + V SL E+ ++ L+I S +L+D +V V + DVN+H P F +
Sbjct: 3264 FRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQ 3323
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y+ V E V+ V ATD D N+++TY + + F I P G L V
Sbjct: 3324 DPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKA 3383
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE Y L + A D+G DVNDN P+F+ +
Sbjct: 3384 LDREQASSYSLKLRATDSG-QPPLHEDTDIAIQVADVNDNPPRFFQLN------------ 3430
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
Y T++EN+PIG+ V ++ +D D NG
Sbjct: 3431 --------------YSTTVQENSPIGSKVLQLILSDPDSPENG 3459
Score = 69.3 bits (162), Expect = 8e-10
Identities = 90/330 (27%), Positives = 149/330 (45%), Gaps = 67/330 (20%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V +++ DVND+ P F + Y V + + PI P + + +
Sbjct: 1858 VIIHVRDVNDSPPRFSEQIYEVAI--------------VGPIHPGMELLM---------- 1893
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE------SSHKPVLL-LRKVLDYDAGDK 195
+RA D D S+V+YSI +GN D + S P L L + L A D
Sbjct: 1894 -VRASDED------SEVNYSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIRASDG 1946
Query: 196 EFQ---LVIMASGKRIHKEILFPEPIH--AIDQDLG-------VGA-------TLRYELI 236
+Q LV ++ + + K + F + ++ A+ ++L +GA TL Y L+
Sbjct: 1947 LYQDTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLSYFLL 2006
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+G D +F + G L + + D E Q +T L V+ P + AQ V + +
Sbjct: 2007 NGTD--MFHMVQSAGVL-QTRGVAFDRE---QQDTHELAVEVRDNRTPQRVAQGLVRVSI 2060
Query: 297 LDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
D+NDN P+F+ + +Y I I + G + QV ATD+D G NG TY+ + F ID
Sbjct: 2061 EDVNDNPPKFKHLPYYTI-IQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRID 2119
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
P G ++++ D +A + +KV A++
Sbjct: 2120 PYLGDISLKKP--FDYQALNKYHLKVIARD 2147
Score = 68.1 bits (159), Expect = 2e-09
Identities = 109/462 (23%), Positives = 184/462 (39%), Gaps = 43/462 (9%)
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTG---TVSVAESPILEGRHALFVEASDQPANP 545
LG G L D L T F + + G T VA + H L VE D N
Sbjct: 1990 LGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRD---NR 2046
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQ 603
+ +R + +V + + + P P F PY + G + Q+ D
Sbjct: 2047 TPQRVAQGLVRVSIE--DVNDNP--PKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTN 2102
Query: 604 NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
V+Y+ Y F ++ G I++ Y + +A ++ S+ +
Sbjct: 2103 GAVTYEFAEDYTY---FRIDPYLGDISLKKPFDYQALNKYHLKVIA-RDGGTPSLQSEEE 2158
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V +V V ++ L + + + V EN I HT S G + + I +
Sbjct: 2159 V-LVTVRNKSNPLFQSPYYKV--RVPENIT--LYTPILHTQARSPEGL---RLIYNIVEE 2210
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDEND 782
+ + + G + PLD E + + TV A + G S A V + +ED ND
Sbjct: 2211 EPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEA---TVEVLVEDVND 2267
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM---FDV 839
NPP F Y I E T + + A+D D G N Y + +G ++ F +
Sbjct: 2268 NPPTFSQLVYTTSISEGLPAQTPVIQ---LLASDQDSGRNRDVSYQIVEDGSDVSKFFQI 2324
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
+ +TG + + LD E + + + + A D G L+ E +++ + D NDN PEF Q +
Sbjct: 2325 NGSTGEMSTV-QELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQ 2383
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL 939
+ V ++L T G +++V+ + + D +L L L
Sbjct: 2384 YEANV-----SEL-ATCGHLVLKVQAIDPDSRDTSRLEYLIL 2419
Score = 65.7 bits (153), Expect = 9e-09
Identities = 44/138 (31%), Positives = 70/138 (50%), Gaps = 6/138 (4%)
Query: 231 LRYELISGNDRKLFSLDS--VNGSLFLE---KELDLDAEHNLQANTFVLQVQASQLNNPL 285
+RY +ISG+ +F + V FL K + + +++ L +QA++ L
Sbjct: 69 VRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEKTLEL 128
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A RV + +LD ND P F Y ++I E++P + +V ATD D G+N EF Y
Sbjct: 129 E-ALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAF 187
Query: 346 DDPKGAFSIDPRSGWLTV 363
+ F+I P SG +TV
Sbjct: 188 NTRSEMFAIHPTSGVVTV 205
Score = 65.7 bits (153), Expect = 9e-09
Identities = 45/130 (34%), Positives = 66/130 (50%), Gaps = 11/130 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L+Y L ++ F L++ G + K +D + Q + QAS +
Sbjct: 393 LQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSPGQASTV--------- 443
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
V I+++D N++ P F Y+ ++ EN+P G SVL V ATD+D GENG TY + PK
Sbjct: 444 -VVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKA 502
Query: 351 -AFSIDPRSG 359
FSIDP G
Sbjct: 503 LPFSIDPYLG 512
Score = 65.3 bits (152), Expect = 1e-08
Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 8/145 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L + + SGN F + V G L ++LD + + + +L+V
Sbjct: 1159 LDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENK-----DEHILEVT 1213
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP--NGFSVLQVMATDKDQ 335
P + +RV + +LD+NDN P F +N+ + E L + V +++A+D D+
Sbjct: 1214 VLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDE 1273
Query: 336 GENGEFTYQLDDP-KGAFSIDPRSG 359
G NG TY ++D + AFSID +G
Sbjct: 1274 GLNGRVTYSIEDSYEEAFSIDLVTG 1298
Score = 65.3 bits (152), Expect = 1e-08
Identities = 45/164 (27%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P IHA D D + L Y+++ K F +D G+L + E+D ++ + Q +V
Sbjct: 1784 PFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVH 1843
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ L P A+V I + D+ND+ P F Y ++IV + G +L V A+D+D
Sbjct: 1844 DQGSPVLFAP---RPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDED 1900
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLR 378
N ++ + + A +I P +G ++V N L ++R
Sbjct: 1901 SEVN--YSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIR 1942
Score = 64.5 bits (150), Expect = 2e-08
Identities = 64/218 (29%), Positives = 90/218 (41%), Gaps = 22/218 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++P GT + L+A D D G G++RY + F ++ G
Sbjct: 934 VPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAH--------------GTFRVDLMTG 979
Query: 1000 HVIVARSLPPESEFRLNIS--ALDGGN---LNDNISVRVFVKDVND--HFPVFKKTWYNF 1052
+I+ R L E N+S A DGG V V V DVN+ H P F +
Sbjct: 980 ALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQG 1039
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
V+E + + V A D D G + L YF++ F I+ TG++ LDRE
Sbjct: 1040 QVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREF 1099
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y LTV+A D G D NDN P+
Sbjct: 1100 ASYYWLTVLAVDRG-SVPLSSVTEVYIEVTDANDNPPQ 1136
Score = 64.5 bits (150), Expect = 2e-08
Identities = 109/480 (22%), Positives = 195/480 (40%), Gaps = 73/480 (15%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
II V P ++ A + IPE+IP+G+ I+ ++A+ ++ YE
Sbjct: 1647 IIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMS-----PSEVTYELREG---- 1697
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFV 1035
+ D + F +N G + + L E S ++L I + ++ V V +
Sbjct: 1698 ----NKDGV-----FSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDI 1748
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQ-YTRRVLGK------VDATDADFGQNANLTYFIQPSD 1088
D ND+ P+F K+ + + EA ++ K + A+D+D N+ L Y I +
Sbjct: 1749 IDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPE 1808
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDN 1147
F+I P G L++ E+D E+ + V D G DVND+
Sbjct: 1809 ALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDS 1868
Query: 1148 SPKF--YAFDELLEWK-HPEADEL--SNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
P+F ++ + HP + L + +S + + +E I +
Sbjct: 1869 PPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSEVNYSIKTGNADEAVTIHPVTGSISVL 1928
Query: 1203 DTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY 1262
+ F+G L + + + GL TA++ +++ V D+ D+ V Y
Sbjct: 1929 NPAFLGLSRKLTI--------RASDGL--YQDTALVKISLTQVLDKSLQFDQDV-----Y 1973
Query: 1263 ELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDT--DIRRTFVIDPRNGTLYLVRS 1320
++EN+ LV L ++ N + Y++LN D ++ V+ R G +
Sbjct: 1974 WAAVKENLQDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTR-GVAF---- 2028
Query: 1321 PDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
DRE +DT+E+ V + + V +G+ + V I+DVNDN PKF
Sbjct: 2029 -DREQQDTHELAVEVRDNR-----------TPQRVAQGLVR------VSIEDVNDNPPKF 2070
Score = 64.5 bits (150), Expect = 2e-08
Identities = 69/301 (22%), Positives = 129/301 (42%), Gaps = 17/301 (5%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V V+DVND+ P F + Y ++ E + + ++ A+D D G+N +++Y I +
Sbjct: 2257 TVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGS 2316
Query: 1090 DLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
D+ F+I+ TG +S ELD E + + + V A D G D+NDN
Sbjct: 2317 DVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKG-DPPLTGETLVVVNVSDINDN 2375
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI 1207
P+F EL+ V+ + + + + + + FI
Sbjct: 2376 PPEFRQ-----PQYEANVSELATCG-HLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFI 2429
Query: 1208 GNGNGLI-LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYELE 1265
+ +G+I +++L ++ + L +S + TV + + P F YE E
Sbjct: 2430 NSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLYEAE 2489
Query: 1266 IEENVNAPVELVSLNLTEHYEN--FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+ EN +++ L + + Y I+N+ ++ F I+P NG + ++ DR
Sbjct: 2490 LAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASE---KFSINP-NGQIATLQKLDR 2545
Query: 1324 E 1324
E
Sbjct: 2546 E 2546
Score = 63.7 bits (148), Expect = 4e-08
Identities = 51/157 (32%), Positives = 74/157 (47%), Gaps = 9/157 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ L+Y L +G FS++ G ++ LD E A+ + L V
Sbjct: 1054 VAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTG--MIQTLAPLDREF---ASYYWLTVL 1108
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + ++ V IE+ D NDN P+ + SI E+ P G SVLQ+ A D D
Sbjct: 1109 AVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSS 1168
Query: 338 NGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDRE 372
G+ T+ + G F I P +G L+ Q LDRE
Sbjct: 1169 KGKLTFNITSGNYMGFFMIHPVTGLLSTAQQ--LDRE 1203
Score = 63.7 bits (148), Expect = 4e-08
Identities = 51/175 (29%), Positives = 82/175 (46%), Gaps = 12/175 (6%)
Query: 218 IHAIDQDLGVGATLRYELIS---GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ AID+D G + Y L + N +LF++DS +G + +ELD + T+
Sbjct: 2819 VTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCET-----CQTYHF 2873
Query: 275 QVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
V A ++ ++QA V++ + D NDN P F + Y S+VEN G V + D
Sbjct: 2874 HVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDA 2933
Query: 334 DQGE-NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D E N + T + DP G F I + ++ LDRE + ++V A +
Sbjct: 2934 DISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASD 2988
Score = 62.9 bits (146), Expect = 7e-08
Identities = 46/139 (33%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ G+ F + V + LD EH + ++L+V AS + A VEI
Sbjct: 2946 ITEGDPLGQFGISQVGDEWRISSRKTLDREHTAK---YLLRVTAS---DGKFQASVTVEI 2999
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-AFS 353
+LD+NDN P+ Y + E++ G +L+V ATD D N + TY L P F
Sbjct: 3000 FVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFK 3059
Query: 354 IDPRSGWLTVRNQTVLDRE 372
+DP +G LT T LDRE
Sbjct: 3060 LDPHTGELT--TLTALDRE 3076
Score = 62.1 bits (144), Expect = 1e-07
Identities = 75/300 (25%), Positives = 133/300 (44%), Gaps = 49/300 (16%)
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL-------------- 174
++P T+ G + + +RA D D+ N++VHYS++ GN +G F +
Sbjct: 1563 SVPDTIAPGTELLQ-VRAMDADRG--VNAEVHYSLLKGNSEGFFNINALLGIITLAQKLD 1619
Query: 175 ESSHKPVLLLRKVLDYDAGD-KEFQLVIM------ASGKRIHKEILF---PEPIHAIDQD 224
+++H P L K D + + VI+ S K F PE I
Sbjct: 1620 QANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPI 1679
Query: 225 LGVGAT----LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
L V A + YEL GN +FS++S +G + +K+LD + + +++ L+++ S
Sbjct: 1680 LLVSAMSPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHE-----KISSYQLKIRGSN 1734
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ-------VMATDK 333
+ V ++++D NDN P F + I E P ++ + A+D
Sbjct: 1735 MAGAF--TDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDS 1792
Query: 334 DQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
D+ N Y++ +P+ F IDP G LT+ ++ +D E+ S + VY + V+
Sbjct: 1793 DKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSE--MDYESMPSFQFCVYVHDQGSPVL 1850
Score = 61.3 bits (142), Expect = 2e-07
Identities = 80/324 (24%), Positives = 126/324 (38%), Gaps = 31/324 (9%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-----KAFIFLIAPIGPSLTI 130
Q+S+ V V I D NDN P F Y +V E + GE K I+ +T
Sbjct: 2885 QLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTC 2944
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNS-----DVHYSIVSGNDDGHFALESSHKPVLLLR 185
+T L F + D + ++ + Y + DG F + + +L
Sbjct: 2945 YITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVL-- 3002
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEIL---FPEPIHAIDQDLGVGATLRYELISGNDRK 242
D D Q + ++H+++ F + A D D A + Y L G
Sbjct: 3003 -----DVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSL-HGPGAH 3056
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F LD G L LD + + V + A + ++ QA + + + D+NDN
Sbjct: 3057 EFKLDPHTGELTTLTALDRERKD-------VFNLVAKATDGGGRSCQADITLHVEDVNDN 3109
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWL 361
P F +++ +N V V A D DQG N + Y L D +G FSID +G
Sbjct: 3110 APRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTG-- 3167
Query: 362 TVRNQTVLDREAHSSLRMKVYAKE 385
+R + L + L + V A +
Sbjct: 3168 VIRLEKPLQVRPQAPLELTVRASD 3191
Score = 60.1 bits (139), Expect = 5e-07
Identities = 94/420 (22%), Positives = 167/420 (39%), Gaps = 44/420 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I + G + +++A D D G NG + YEF +E Y YF I+
Sbjct: 2078 IIQDGTEPGDVLFQVSATDEDLGTNGAVTYEF-AEDYT--------------YFRIDPYL 2122
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + + + ++ ++ L + A DGG + V V N P+F+ +Y V E
Sbjct: 2123 GDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPE 2182
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ + T A + L Y I + + F TGVL+V G LD E++ K+
Sbjct: 2183 ---NITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKH 2239
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF------YAFDELLEWKHPEADELSN 1170
+ TV A D DVNDN P F + E L + P L++
Sbjct: 2240 VFTVRATD--TALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLAS 2297
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVF-ANDTDFIGNGNGLILYSLPQ----RKNQQ 1225
+S V +E+ G+ V+K F N + + + Y Q +
Sbjct: 2298 DQ-DSGRNRDVSYQIVED----GSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAM 2352
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+ G P L+ +++V V+D+ D +P + + EL ++ V+ + +
Sbjct: 2353 DKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAID---PDSR 2409
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+ ++ Y IL+ N R F I+ +G + + + + +Y + V A + +P
Sbjct: 2410 DTSRLEYLILSGNQD---RHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVP 2466
Score = 58.8 bits (136), Expect = 1e-06
Identities = 52/173 (30%), Positives = 84/173 (48%), Gaps = 13/173 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ AIDQD G +L Y + D LF LD +G L +LDL + + +T +
Sbjct: 1470 VQAIDQDKG--KSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPS--QHTLTV 1525
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V+ ++ P+K V I + D N + P F Y S+ + + G +LQV A D D
Sbjct: 1526 MVRDQEI--PIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDAD 1583
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G N E Y L + +G F+I+ G +T+ + LD+ H+ + V A++
Sbjct: 1584 RGVNAEVHYSLLKGNSEGFFNINALLGIITLAQK--LDQANHAPHTLTVKAED 1634
Score = 58.4 bits (135), Expect = 1e-06
Identities = 76/318 (23%), Positives = 129/318 (40%), Gaps = 27/318 (8%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT---VPRGL 138
+V V +EDVNDN P F Y ++ E P L + ++ V G
Sbjct: 2257 TVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGS 2316
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV----LLLRKVLDYDAGD 194
+ K + + ++ Y A++ P+ L++ V D +
Sbjct: 2317 DVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNP 2376
Query: 195 KEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG-- 251
EF Q A+ + + AID D + L Y ++SGN + F ++S +G
Sbjct: 2377 PEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGII 2436
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
S+F + LD+ +NL+ ++ + A V I + N PEF+ Y
Sbjct: 2437 SMFNLCKKHLDSSYNLRVGA----------SDGVFRATVPVYINTTNANKYSPEFQQHLY 2486
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVL 369
+ EN G V+ ++A DKD G G Y + + + FSI+P T++ L
Sbjct: 2487 EAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQK---L 2543
Query: 370 DREAHSS--LRMKVYAKE 385
DRE + + +KV A++
Sbjct: 2544 DRENSTERVIAIKVMARD 2561
Score = 56.8 bits (131), Expect = 4e-06
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 7/167 (4%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISA--LDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F ++ G + V + + ES +++++ A L ++ +SV + V DVND+ PVF+
Sbjct: 2740 FSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEA 2799
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP---SDTDLPFEISPLTGVLSV 1104
Y + E + +V A D D G++ ++Y + S+ F I +G ++
Sbjct: 2800 DPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITT 2859
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
ELD ET Y VVA D+G D NDN+P+F
Sbjct: 2860 LQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRF 2906
Score = 56.8 bits (131), Expect = 4e-06
Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 7/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y L + FS+D+ G + LEK L + + L+ L V+
Sbjct: 3135 VFARDPDQGANAQVVYSLPDSAEGH-FSIDATTGVIRLEKPLQVRPQAPLE-----LTVR 3188
Query: 278 ASQLNNPLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS L P+ + V + ++ L D LP F +++ + E+ P G VLQ+ +
Sbjct: 3189 ASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGA 3248
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTV 363
E + + +G F +D R+G L V
Sbjct: 3249 EKTGYRVVSGNEQGRFRLDARTGILYV 3275
Score = 56.4 bits (130), Expect = 6e-06
Identities = 78/271 (28%), Positives = 104/271 (38%), Gaps = 44/271 (16%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I N+ + +I++ A D D G N + Y N P L D +E IN G
Sbjct: 2594 IQSNVSKDSPVIQVLAYDADEGQNADVTYSVN------PEDLVKDVIE------INPVTG 2641
Query: 1000 HVIVARSLPPESEFRLN--ISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V V SL L+ I A DGG + N + VR+ V P F + Y F+
Sbjct: 2642 VVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAP 2701
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISPLTGVLSVNGELDRETED 1114
E +G V A A +L P S+ D F + P TGV+ V +D E+
Sbjct: 2702 EDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTK 2761
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y + V+A DVNDN P F EAD
Sbjct: 2762 LYQIDVMAHCL-QNTDVVSLVSVNIQVGDVNDNRPVF------------EADP------- 2801
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
YKA + EN P+GT+V +V A D D
Sbjct: 2802 -------YKAVLTENMPVGTSVIQVTAIDKD 2825
Score = 55.2 bits (127), Expect = 1e-05
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
L+RE RD Y T+I + + + + +V ++I D+ND P+F +Y I E+ +
Sbjct: 107 LNREVRDSY--TLIIQATEKTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLK 164
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
+ I + ATDAD G NA F Y F EMF + +GVV G
Sbjct: 165 SPICK---VTATDADLGQNAEFYYA-FNTRSEMFAIHPTSGVVTVAG 207
Score = 54.8 bits (126), Expect = 2e-05
Identities = 50/190 (26%), Positives = 90/190 (47%), Gaps = 19/190 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN +G I+ ++A D D LN I Y I ++L +F I+ + G +
Sbjct: 3332 ENALVGDVILTVSATDEDGPLNSDITYSL-----IGGNQLG--------HFTIHPKKGEL 3378
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VA++L E S + L + A D G L+++ + + V DVND+ P F + Y+ V+E
Sbjct: 3379 QVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQEN 3438
Query: 1058 QYTRRVLGKVDATDADFGQNA-NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ ++ +D D +N ++ I + F ++P +++ G L R ++ Y
Sbjct: 3439 SPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEG-LSRRAQEWY 3497
Query: 1117 ILTVVARDNG 1126
L + A D+G
Sbjct: 3498 QLQIQASDSG 3507
Score = 53.6 bits (123), Expect = 4e-05
Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 2/94 (2%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V + D ND P+F Y + E + + KV ATDAD GQNA Y+ + ++
Sbjct: 134 VVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEF-YYAFNTRSE 192
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+ F I P +GV++V G+L+ K+ L V+A D
Sbjct: 193 M-FAIHPTSGVVTVAGKLNVTWRGKHELQVLAVD 225
Score = 53.2 bits (122), Expect = 5e-05
Identities = 42/126 (33%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + V V +LD ND P+F P + Y ++ + + + I KV A D DLGQN Y
Sbjct: 127 ELEALTRVVVHILDQNDLKPLFSPPS-YRVTISEDMPLKSPICKVTATDADLGQNAEFYY 185
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERR--YSLA 553
S + F I+P +G V+VA + G+H L V A D+ SE SLA
Sbjct: 186 AFNTRSEM-----FAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLA 240
Query: 554 VVTIEV 559
+ + V
Sbjct: 241 ALVVHV 246
Score = 52.8 bits (121), Expect = 7e-05
Identities = 105/426 (24%), Positives = 171/426 (40%), Gaps = 55/426 (12%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVF-VKDVNDHFPVFKKT 1048
F I + G +++AR L S + L + DG V +F + ++N H P F +T
Sbjct: 1393 FDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIAT-QVHIFMIANINHHRPQFLET 1451
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLT-YFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y V + L +V A D D G++ T + Q + F++ P +GVL G+
Sbjct: 1452 RYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGK 1511
Query: 1108 LDRET-EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
LD + ++ LTV+ RD D N + P+F L ++ D
Sbjct: 1512 LDLGSGPSQHTLTVMVRDQ-EIPIKRNFVWVTIHVEDGNLHPPRF----TQLHYEASVPD 1566
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQ 1225
++ ++ + A NA + ++ K N F N N L+ + +L Q+ +Q
Sbjct: 1567 TIAPGT--ELLQVRAMDADRGVNAEVHYSLLK--GNSEGFF-NINALLGIITLAQKLDQA 1621
Query: 1226 NLGLPSLSSTAILMVT-----VADVPDEVEMSDK--PVFISRYYELEIEEN--VNAPVEL 1276
N +L+ A + +A V V SD+ P+F Y +EI E+ V +P+ L
Sbjct: 1622 NHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILL 1681
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
VS Y L E + D F ++ +G + + D E +Y++ +R
Sbjct: 1682 VSAMSPSEVT------YELREGNKD--GVFSMNSYSGLISTQKKLDHEKISSYQLKIR-- 1731
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
++ T DV VVV I D NDN+P F V I AP
Sbjct: 1732 ---------------GSNMAGAFT--DVMVVVDIIDENDNAPMFLKST--FVGQISEAAP 1772
Query: 1397 FGYQVM 1402
+M
Sbjct: 1773 LYSMIM 1778
Score = 49.2 bits (112), Expect = 9e-04
Identities = 59/225 (26%), Positives = 95/225 (42%), Gaps = 20/225 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + + D NDN P F N Y +++ N+ +G+ + ++ DPD +NG Y + T
Sbjct: 3411 DIAIQVADVNDNPPRFFQLN-YSTTVQENSPIGSKVLQLILSDPDSPENGPP-YSFRITK 3468
Query: 504 NLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S F++ P+ G + AE S + + L ++ASD P SL V + VT
Sbjct: 3469 GNN-GSAFRVTPD-GWLVTAEGLSRRAQEWYQLQIQASDSGIPPLS---SLTSVRVHVTE 3523
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
+ P + VG + G VG+I D Q+ ++Y L G F+
Sbjct: 3524 QSHY----APSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFS 3579
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
V G I L R + Y F ++ + T A VHV
Sbjct: 3580 VGAPDGKIIAAQGLPRGH---YSFNVTV----SDGTFTTTAGVHV 3617
Score = 47.2 bits (107), Expect = 0.003
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 24/216 (11%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
+N + T + + A D D G N Q+ Y +P S + +F I+ G +
Sbjct: 3124 DNTTVKTPVAVVFARDPDQGANAQVVYS------LPDS--------AEGHFSIDATTGVI 3169
Query: 1002 IVARSLP--PESEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNV-E 1055
+ + L P++ L + A D G L+ +V V V + D+ PVF T ++ V E
Sbjct: 3170 RLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPE 3229
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
+A VL T + Y + + F + TG+L VN LD ET K
Sbjct: 3230 DAPPGTEVLQLATLTRPGAEKTG---YRVVSGNEQGRFRLDARTGILYVNASLDFETSPK 3286
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y L++ DVN++ P+F
Sbjct: 3287 YFLSIEC-SRKSSSSLSDVTTVMVNITDVNEHRPQF 3321
Score = 46.8 bits (106), Expect = 0.005
Identities = 35/130 (26%), Positives = 67/130 (51%), Gaps = 11/130 (8%)
Query: 236 ISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
ISG D+ + F ++ GS+ + + LD N + L V+ + + + T Q + +
Sbjct: 1384 ISGGDKDMDFDIEKTTGSIVIARPLDTRRRSN-----YNLTVEVTDGSRTIAT-QVHIFM 1437
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT-YQLDDPKGA-- 351
+ ++N + P+F Y + + ++ G +L+V A D+D+G++ +T + DP A
Sbjct: 1438 -IANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASL 1496
Query: 352 FSIDPRSGWL 361
F +DP SG L
Sbjct: 1497 FQLDPSSGVL 1506
Score = 41.5 bits (93), Expect = 0.17
Identities = 44/163 (26%), Positives = 69/163 (42%), Gaps = 28/163 (17%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL--TE 1283
+LG P SS +L V V D D P F Y+L I E+ + L +
Sbjct: 794 DLGTPQKSSWKLLTVNVKDWNDNA-----PRFPPGGYQLTISEDTEVGTTIAELTTKDAD 848
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
+N ++RY +L+ + F + P G L + DRE + Y + V A Q
Sbjct: 849 SEDNGRVRYTLLSPTEK-----FSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKG- 902
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK-FTNGNR 1385
H ++ V + +++ ++DVNDNSP+ T NR
Sbjct: 903 --HQLFSVTD------------LIITLEDVNDNSPQCITEHNR 931
>UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor
suppressor homolog 4 (Drosophila); n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to FAT tumor suppressor
homolog 4 (Drosophila) - Ornithorhynchus anatinus
Length = 1683
Score = 146 bits (354), Expect = 4e-33
Identities = 234/924 (25%), Positives = 374/924 (40%), Gaps = 96/924 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S+ +EV + D NDN P F + + + N V+ V A D D G NG + Y +
Sbjct: 255 SYERLEVEVQDVNDNAPDF-REDPFVAEIAENLPPRRVLA-VAAADRDSGPNGQLDYGIV 312
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIE 558
+ F I+ TG + E R+ L V ASD+ P R + A V +
Sbjct: 313 AGNE---EGHFAIHRATGEIRSTRPLDRESVPRYRLTVRASDRGDPP---RSATARVVVN 366
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVS-YDLLHGYEE 616
V + P A V N +G +V + +D E QN VS Y + +
Sbjct: 367 VL-DENDHSPRFSQLFSAS----VPENAPVGFTVTRATTSDEDEGQNAVSRYSIA---DS 418
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G+PFA++ +G ITV L R + Y A ++ ++ T+ V V DVND
Sbjct: 419 GLPFAIDPSTGDITVSRPLDREDVARYRIRVSA--HDSGWTVSTDVAVAVTDVNDNAPRF 476
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ ++ + E G+ + ++ T+ G V +L+ + + A+ G
Sbjct: 477 REPSYFLECPELPE--VGSGVARVAATDPDE---GPNGQVFYLLKSPSEFFRVDAVT--G 529
Query: 737 TIFTQKPLD--REKRDVY---RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
IF ++PL V+ V+ ++G VT+++ D ND+PP F A
Sbjct: 530 EIFNKQPLRYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAG 589
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIG 850
Y + ++ +GT + + A D D G N+ Y L G E F +D TG V +
Sbjct: 590 YSTPVPKDVSVGTRVIQ--VAAADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVS-VA 646
Query: 851 DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
L + ++LS+ ARD G LS+ A + I++ + N + PEF + +VR+
Sbjct: 647 APLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANAHTPEFPR----DRVRVEVPE 702
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
L A ++ + D + G LF P GT + L A D + ++ + R
Sbjct: 703 TLAVGAVVCVLAARDS-----DPAENGLLFYA---FPPGTGVSYLAAED-EQEVSIKSRV 753
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN-- 1024
E+ P ++ DA G V VA L + + FRL+++A DGG
Sbjct: 754 EYLLTGQEPAARFGLDA-----------ETGWVSVAAPLTGDVDRTFRLSVTARDGGRPP 802
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
L+ +VR+ V + N H P F + V E V+ + A DAD +N L Y +
Sbjct: 803 LSAGATVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDADPAENGLLAYAV 862
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ + F ++ TGVL++ G LD ET + +TV A D G DV
Sbjct: 863 SAGNGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDGG-WAARTGFCAVTVDVLDV 921
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
NDN P F + PE E N S + +AT ++ P + D
Sbjct: 922 NDNPPVFAGAEYT-----PEVAE----NAPSGTPVVTLRATDADSGPNAVVAYALHEADG 972
Query: 1205 DF--------IGNGNGLILYSL--PQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
D + + G + Y R + +P A VTV V E
Sbjct: 973 DLFAVDPNTGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVR-VTGVNEYI-- 1029
Query: 1255 PVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRN 1312
P F+S Y E+ E PV V + + ++ Y + E+ R+ F ++
Sbjct: 1030 PRFVSAAYGFEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESR---RKGFRVERET 1086
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAE 1336
G + + DRE + T + V A+
Sbjct: 1087 GQISVAGPLDREREGTVALRVLAK 1110
Score = 135 bits (326), Expect = 1e-29
Identities = 139/468 (29%), Positives = 199/468 (42%), Gaps = 39/468 (8%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
F V V +LD NDN PVF + Y + NA GT + ++A D D G N +V Y L
Sbjct: 911 FCAVTVDVLDVNDNPPVFAGAE-YTPEVAENAPSGTPVVTLRATDADSGPNAVVAYALHE 969
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEV 559
F ++PNTG VS E R H L V+A + P E R + A VT+ V
Sbjct: 970 ADG----DLFAVDPNTGVVSTQGFLDYETRREHRLTVKAFNV---PDEERCAFAAVTVRV 1022
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEG 617
T G IP F+ A Y F V GT VGQ+ D +VSY LL G
Sbjct: 1023 T----GVNEYIPRFVSAAYGFEVSEAAPPGTPVGQVFAGDRDRGPDGEVSY-LLFGESRR 1077
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F VE +G I+V L R +A N + A V V VN V +
Sbjct: 1078 KGFRVERETGQISVAGPLDREREGTVALRVLA----KNAGPIRGADVDEVAVN----VTV 1129
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV----RFLIANQQDVTDDIAI- 732
A+ P +F + + G T+++ + +V RF D ++
Sbjct: 1130 LDANDPPVFGAETYRVRISEGVPPGTHVTFVGAADADSVPAWSRFSYRVGPAGGDAFSVH 1189
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G + PLDRE VY +TV+A + G G + + +ED NDN PV
Sbjct: 1190 PQTGQVTVTAPLDRETLPVYNLTVLA-VDTGTPPATGRAVLLVTLEDVNDNGPVL--TVG 1246
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
E + EN GT + ++A+D D N F + L G G + +
Sbjct: 1247 EARVAENQPPGTVV---TTLRASDPDLPPNQGPFTFRLLGGGPAADYFGLSPAGLLTTAR 1303
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+DRE+ + L +V RD+G +SS ++I++ D NDN + +E
Sbjct: 1304 EIDREQVSRFLLPVVVRDSGLPPMSSTGTVLILVADRNDNPSQPRPLE 1351
Score = 120 bits (288), Expect = 4e-25
Identities = 133/463 (28%), Positives = 199/463 (42%), Gaps = 34/463 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V + + +AN + P F P + + VG V+ + A D D +NG++ Y
Sbjct: 803 LSAGATVRILVTEANAHTPEF-PRDRVRVEVPETLAVGAVVCVLAARDADPAENGLLAYA 861
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE-GR-HALFVEASDQPANPSERRYSLAVVT 556
+ + + F +N +TG +++A + E GR H + V A+D R VT
Sbjct: 862 VSAGNGEGL---FAVNASTGVLTLAGALDYETGRSHEVTVSATD---GGWAARTGFCAVT 915
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYE 615
++V + P P F GA Y V N GT V +R DA N V LH
Sbjct: 916 VDVL--DVNDNP--PVFAGAEYTPEVAENAPSGTPVVTLRATDADSGPNAVVAYALH-EA 970
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERG 674
+G FAV+ +GV++ L R + A + TV V VN+
Sbjct: 971 DGDLFAVDPNTGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVRVTGVNEYIP 1030
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ A+ F V E + G +GQ+F + G V +L+ +
Sbjct: 1031 RFVSAAYG---FEVSEAAPPGTPVGQVFAGDRDR---GPDGEVSYLLFGESRRKGFRVER 1084
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHAT 791
E G I PLDRE+ + V+A+ N G I GA + +V + + D ND PPVF T
Sbjct: 1085 ETGQISVAGPLDREREGTVALRVLAK-NAGPIRGADVDEVAVNVTVLDAND-PPVFGAET 1142
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y I E GT + + A DAD + F Y + G + F V TG V +
Sbjct: 1143 YRVRISEGVPPGTHV---TFVGAADADSVPAWSRFSYRVGPAGGDAFSVHPQTGQVT-VT 1198
Query: 851 DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LDRE +Y L+++A DTG + A L++ + D NDN P
Sbjct: 1199 APLDRETLPVYNLTVLAVDTGTPPATGRAVLLVTLEDVNDNGP 1241
Score = 110 bits (264), Expect = 3e-22
Identities = 181/705 (25%), Positives = 289/705 (40%), Gaps = 73/705 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD-LDAEHNLQANTFVLQV 276
+ A D D G + Y L S ++ F +D+V G +F ++ L L+ ++ AN V
Sbjct: 498 VAATDPDEGPNGQVFYLLKSPSE--FFRVDAVTGEIFNKQPLRYLNGTGSVHANRHSFVV 555
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK-DQ 335
S +P ++ V + ++D ND+ P F Y+ + +++ G V+QV A D D
Sbjct: 556 TCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDF 615
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
G N Y L +P F +D +GW++V L + + R+ V A++ +
Sbjct: 616 GLNSRVEYLLTGQEPAARFGLDAETGWVSV--AAPLTGDVDRTFRLSVTARDGGRPPLSA 673
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFP-DKVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
A + + E NA T FP D+V + E L V V +L A
Sbjct: 674 GATVRILV------TEANA----HTPEFPRDRVRVEV------PETLA--VGAVVCVLAA 715
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD-PDLGQNGMVLYDLQRTSNLTITSPF 511
D++P Y F GT + + A D ++ V Y L + + F
Sbjct: 716 RDSDPAENGLLFYAF------PPGTGVSYLAAEDEQEVSIKSRVEYLL---TGQEPAARF 766
Query: 512 KINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
++ TG VSVA +P+ ++ L V A D P ++ ++ E T
Sbjct: 767 GLDAETGWVSVA-APLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANAHT----- 820
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGVPFAVEERS 626
P+F V + +G V + DA E ++Y + G EG+ FAV +
Sbjct: 821 --PEFPRDRVRVEVPETLAVGAVVCVLAARDADPAENGLLAYAVSAGNGEGL-FAVNAST 877
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
GV+T+ L ++ A A + TV V+DVND V ++P
Sbjct: 878 GVLTLAGALDYETGRSHEVTVSATDGGWAARTGFCAVTVDVLDVNDNPPVFAGAEYTP-- 935
Query: 686 FHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPL 744
V EN+ +G + + T+ S G V ++ D G + TQ L
Sbjct: 936 -EVAENAPSGTPVVTLRATDADS----GPNAVVAYALHEADGDLFAVDPNTGVVSTQGFL 990
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
D E R +R+TV A FN VT+ + N+ P F A Y + E + GT
Sbjct: 991 DYETRREHRLTVKA-FNVPDEERCAFAAVTVRVTGVNEYIPRFVSAAYGFEVSEAAPPGT 1049
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKL 863
+ + A D D G + Y LFGE + F V+ TG + G LDRE++ L
Sbjct: 1050 PVGQ---VFAGDRDRGPDGEVSYLLFGESRRKGFRVERETGQISVAG-PLDREREGTVAL 1105
Query: 864 SLVARDTGGLS----SEAELIIMIGDENDNKPEFNQIEENSKVRI 904
++A++ G + E + + + D ND P F E +VRI
Sbjct: 1106 RVLAKNAGPIRGADVDEVAVNVTVLDAND-PPVFG--AETYRVRI 1147
Score = 92.7 bits (220), Expect = 7e-17
Identities = 55/173 (31%), Positives = 94/173 (54%), Gaps = 8/173 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G L Y +++GN+ F++ G + + LD ++ + L V+
Sbjct: 294 VAAADRDSGPNGQLDYGIVAGNEEGHFAIHRATGEIRSTRPLDRES-----VPRYRLTVR 348
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS +P ++A ARV + +LD ND+ P F ++ S+ EN P GF+V + +D+D+G+
Sbjct: 349 ASDRGDPPRSATARVVVNVLDENDHSPRFS-QLFSASVPENAPVGFTVTRATTSDEDEGQ 407
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
N Y + D F+IDP +G +TV LDRE + R++V A ++ +V
Sbjct: 408 NAVSRYSIADSGLPFAIDPSTGDITVSRP--LDREDVARYRIRVSAHDSGWTV 458
Score = 84.2 bits (199), Expect = 2e-14
Identities = 106/430 (24%), Positives = 173/430 (40%), Gaps = 47/430 (10%)
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF 535
G + V DPD G N + + L + + F+I+P G ++ AE E
Sbjct: 86 GLFVFAVTVTDPDTGPNSELHFSLSGSHS----ERFRIDPTRGAITAAEPLAGEAEVTFS 141
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
V D +P T+ V G D P F + +G+ V +
Sbjct: 142 VHVRDGGRSPQADS-----TTVTVRFAAAG---DFPRVRAEGRSFLFPESQQVGSPVTVV 193
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL----- 650
+ +SY + G G F ++ +G +T RP+ DFEA+
Sbjct: 194 -TGTSSRAGPLSYHVASGNFGGA-FHADQLTGQVTT-------GRPL-DFEAIQRFVVWI 243
Query: 651 -QENANL---SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
+A S V V DVND + P + + EN + + +
Sbjct: 244 EARDAGFPPFSSYERLEVEVQDVNDNAPDFRE---DPFVAEIAENLPPRRVLAVAAADRD 300
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
S NG + + N++ AI G I + +PLDRE YR+TV A ++G
Sbjct: 301 S-GPNGQLDYGIVAGNEEG---HFAIHRATGEIRSTRPLDRESVPRYRLTVRAS-DRGDP 355
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ +V + + DEND+ P F + + EN+ +G + +D DEG NA+
Sbjct: 356 PRSATARVVVNVLDENDHSPRFSQL-FSASVPENAPVGFTVTRAT---TSDEDEGQNAVS 411
Query: 826 MYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD 885
Y++ G F +D +TG + + LDRE Y++ + A D+G S ++ + + D
Sbjct: 412 RYSIADSGLP-FAIDPSTGDIT-VSRPLDREDVARYRIRVSAHDSGWTVS-TDVAVAVTD 468
Query: 886 ENDNKPEFNQ 895
NDN P F +
Sbjct: 469 VNDNAPRFRE 478
Score = 80.2 bits (189), Expect = 4e-13
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 16/184 (8%)
Query: 210 KEILFPE------PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
+ LFPE P+ + L Y + SGN F D + G + + LD +A
Sbjct: 176 RSFLFPESQQVGSPVTVVTGTSSRAGPLSYHVASGNFGGAFHADQLTGQVTTGRPLDFEA 235
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
FV+ ++A P ++ R+E+E+ D+NDN P+F D + I ENLP
Sbjct: 236 -----IQRFVVWIEARDAGFPPFSSYERLEVEVQDVNDNAPDFREDPFVAEIAENLPPR- 289
Query: 324 SVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
VL V A D+D G NG+ Y + + +G F+I +G +R+ LDRE+ R+ V
Sbjct: 290 RVLAVAAADRDSGPNGQLDYGIVAGNEEGHFAIHRATG--EIRSTRPLDRESVPRYRLTV 347
Query: 382 YAKE 385
A +
Sbjct: 348 RASD 351
Score = 69.3 bits (162), Expect = 8e-10
Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRY---EFNSEVY-IPPSKLSADALEVKRYFVIN 995
+ EN P GT ++ L A D DSG N + Y E + +++ + P + + + +
Sbjct: 937 VAENAPSGTPVVTLRATDADSGPNAVVAYALHEADGDLFAVDP---NTGVVSTQGFLDYE 993
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
R H + ++ E R +A V V V VN++ P F Y F V
Sbjct: 994 TRREHRLTVKAFNVPDEERCAFAA-----------VTVRVTGVNEYIPRFVSAAYGFEVS 1042
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
EA +G+V A D D G + ++Y + F + TG +SV G LDRE E
Sbjct: 1043 EAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESRRKGFRVERETGQISVAGPLDREREGT 1102
Query: 1116 YILTVVARDNG 1126
L V+A++ G
Sbjct: 1103 VALRVLAKNAG 1113
Score = 66.9 bits (156), Expect = 4e-09
Identities = 73/295 (24%), Positives = 113/295 (38%), Gaps = 20/295 (6%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE-LTPTGEKAFIFLIAPIGPSLTI 130
AG S+Y + V ++DVNDN P F + P+ + E L P A GP+ +
Sbjct: 248 AGFPPFSSYERLEVEVQDVNDNAPDFREDPFVAEIAENLPPRRVLAVAAADRDSGPNGQL 307
Query: 131 PLTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
+ G I + +P S Y + V +D G ++ + V+
Sbjct: 308 DYGIVAGNEEGHFAIHRATGEIRSTRPLDRESVPRYRLTVRASDRGDPPRSATARVVV-- 365
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
VLD + F + AS D+D G A RY + F
Sbjct: 366 -NVLDENDHSPRFSQLFSASVPENAPVGFTVTRATTSDEDEGQNAVSRYSIADSG--LPF 422
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
++D G + + + LD + + ++V A T V + + D+NDN P
Sbjct: 423 AIDPSTGDITVSRPLDRE-----DVARYRIRVSAHDSG---WTVSTDVAVAVTDVNDNAP 474
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
F Y + E G V +V ATD D+G NG+ Y L P F +D +G
Sbjct: 475 RFREPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLKSPSEFFRVDAVTG 529
Score = 64.5 bits (150), Expect = 2e-08
Identities = 65/219 (29%), Positives = 91/219 (41%), Gaps = 23/219 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E P GT + ++ A D D G +G++ Y E ++ F +
Sbjct: 1039 FEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGE-------------SRRKGFRVERE 1085
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNLN----DNISVRVFVKDVNDHFPVFKKTWYN 1051
G + VA L E E L + A + G + D ++V V V D ND PVF Y
Sbjct: 1086 TGQISVAGPLDREREGTVALRVLAKNAGPIRGADVDEVAVNVTVLDANDP-PVFGAETYR 1144
Query: 1052 FNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+ E + V A DAD + +Y + P+ D F + P TG ++V LDR
Sbjct: 1145 VRISEGVPPGTHVTFVGAADADSVPAWSRFSYRVGPAGGD-AFSVHPQTGQVTVTAPLDR 1203
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
ET Y LTV+A D G DVNDN P
Sbjct: 1204 ETLPVYNLTVLAVDTG-TPPATGRAVLLVTLEDVNDNGP 1241
Score = 63.3 bits (147), Expect = 5e-08
Identities = 107/437 (24%), Positives = 165/437 (37%), Gaps = 63/437 (14%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKK 1047
F ++ G V R L E+ F + I A D G + + V V+DVND+ P F++
Sbjct: 216 FHADQLTGQVTTGRPLDFEAIQRFVVWIEARDAGFPPFSSYERLEVEVQDVNDNAPDFRE 275
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
+ + E RRVL V A D D G N L Y I + + F I TG +
Sbjct: 276 DPFVAEIAENLPPRRVLA-VAAADRDSGPNGQLDYGIVAGNEEGHFAIHRATGEIRSTRP 334
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE+ +Y LTV A D G D ND+SP+ F +L PE
Sbjct: 335 LDRESVPRYRLTVRASDRG-DPPRSATARVVVNVLDENDHSPR---FSQLFSASVPE--- 387
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
NAP+G TV + +D D N + YS+ +
Sbjct: 388 ---------------------NAPVGFTVTRATTSDED--EGQNAVSRYSI------ADS 418
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
GLP + +TV+ D +++ + +S + + V+ V + ++ ++
Sbjct: 419 GLPFAIDPSTGDITVSRPLDREDVARYRIRVSAH---DSGWTVSTDVAVAVTDVNDNAPR 475
Query: 1288 FKMRYYILN-----ENDTDIRRTFVIDPRNG----TLYLVRSPDR--EVKDTYEVIVRAE 1336
F+ Y L E + + R DP G YL++SP V I +
Sbjct: 476 FREPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLKSPSEFFRVDAVTGEIFNKQ 535
Query: 1337 RQKYSREL------PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA 1390
+Y H D + V V + D ND+ P+F + T
Sbjct: 536 PLRYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAG--YSTP 593
Query: 1391 IPTTAPFGYQVMQLKGA 1407
+P G +V+Q+ A
Sbjct: 594 VPKDVSVGTRVIQVAAA 610
Score = 58.4 bits (135), Expect = 1e-06
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y L + RK F ++ G + + LD + E T L+V
Sbjct: 1054 VFAGDRDRGPDGEVSYLLFGESRRKGFRVERETGQISVAGPLDRERE-----GTVALRVL 1108
Query: 278 ASQLNNPLKTA---QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A P++ A + V + +LD ND P F + Y + I E +P G V V A D D
Sbjct: 1109 AKNAG-PIRGADVDEVAVNVTVLDANDP-PVFGAETYRVRISEGVPPGTHVTFVGAADAD 1166
Query: 335 QGEN-GEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVV 391
F+Y++ G AFS+ P++G +TV LDRE + V A +T P
Sbjct: 1167 SVPAWSRFSYRVGPAGGDAFSVHPQTGQVTV--TAPLDRETLPVYNLTVLAVDTGTPPAT 1224
Query: 392 G 392
G
Sbjct: 1225 G 1225
Score = 58.0 bits (134), Expect = 2e-06
Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 11/165 (6%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ-VTIYIEDENDNPPVFEHATYEG 794
G + T +PLD E + R V E Y+ + + ++D NDN P F +
Sbjct: 223 GQVTTGRPLDFEA--IQRFVVWIEARDAGFPPFSSYERLEVEVQDVNDNAPDFREDPFVA 280
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSL 853
I EN + + A D D G N Y + +E F + TG ++ L
Sbjct: 281 EIAENLPPRRVLA----VAAADRDSGPNGQLDYGIVAGNEEGHFAIHRATGEIRSTRP-L 335
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQI 896
DRE Y+L++ A D G S+ A +++ + DEND+ P F+Q+
Sbjct: 336 DRESVPRYRLTVRASDRGDPPRSATARVVVNVLDENDHSPRFSQL 380
Score = 53.2 bits (122), Expect = 5e-05
Identities = 107/454 (23%), Positives = 170/454 (37%), Gaps = 71/454 (15%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
P +P G + + D D+G N ++ + LS E F I+ G
Sbjct: 80 PRRLPAGLFVFAVTVTDPDTGPNSELHFS-----------LSGSHSE---RFRIDPTRGA 125
Query: 1001 VIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK-DVNDHFPVFKKTWYNFNVEEAQY 1059
+ A L E+E ++ DGG S V V+ FP + +F E+Q
Sbjct: 126 ITAAEPLAGEAEVTFSVHVRDGGRSPQADSTTVTVRFAAAGDFPRVRAEGRSFLFPESQQ 185
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ V T + G L+Y + + F LTG ++ LD E ++++
Sbjct: 186 VGSPVTVVTGTSSRAGP---LSYHVASGNFGGAFHADQLTGQVTTGRPLDFEAIQRFVVW 242
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
+ ARD G DVNDN+P F + P E++ N ++
Sbjct: 243 IEARDAG-FPPFSSYERLEVEVQDVNDNAPDFR--------EDPFVAEIA-ENLPPRRVL 292
Query: 1180 PVYKATIEENAPIGTTVAKVFAND----------TDFIGNGNGLILYSLPQRK---NQQN 1226
V A ++ P G + A + T I + L S+P+ + +
Sbjct: 293 AV-AAADRDSGPNGQLDYGIVAGNEEGHFAIHRATGEIRSTRPLDRESVPRYRLTVRASD 351
Query: 1227 LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
G P S+TA ++V V D E P F S+ + + E NAPV T E
Sbjct: 352 RGDPPRSATARVVVNVLD-----ENDHSPRF-SQLFSASVPE--NAPVGFTVTRATTSDE 403
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
+ + + + + D F IDP G + + R DRE Y + V A ++
Sbjct: 404 D-EGQNAVSRYSIADSGLPFAIDPSTGDITVSRPLDREDVARYRIRVSAHDSGWT----- 457
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
V+ D V V + DVNDN+P+F
Sbjct: 458 ----VSTD-----------VAVAVTDVNDNAPRF 476
Score = 46.4 bits (105), Expect = 0.006
Identities = 55/193 (28%), Positives = 87/193 (45%), Gaps = 22/193 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +P GT + + A D DS + R+ + + P+ DA F ++ + G
Sbjct: 1147 ISEGVPPGTHVTFVGAADADS-VPAWSRFSYR----VGPA--GGDA------FSVHPQTG 1193
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V V L E+ + L + A+D G + V ++DVND+ PV T V
Sbjct: 1194 QVTVTAPLDRETLPVYNLTVLAVDTGTPPATGRAVLLVTLEDVNDNGPVL--TVGEARVA 1251
Query: 1056 EAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETE 1113
E Q V+ + A+D D N T+ + F +SP G+L+ E+DRE
Sbjct: 1252 ENQPPGTVVTTLRASDPDLPPNQGPFTFRLLGGGPAADYFGLSP-AGLLTTAREIDREQV 1310
Query: 1114 DKYILTVVARDNG 1126
+++L VV RD+G
Sbjct: 1311 SRFLLPVVVRDSG 1323
Score = 37.1 bits (82), Expect = 3.7
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1441 ATDSDIGINADIRYQILNEQ-APRFAIDPVSGTVRVVAALARDAGRVF 1487
A D D G+N+ + Y + ++ A RF +D +G V V A L D R F
Sbjct: 610 ADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTF 657
>UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
sequence; n=4; Eumetazoa|Rep: Chromosome 7 SCAF14601,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 2970
Score = 146 bits (354), Expect = 4e-33
Identities = 170/649 (26%), Positives = 289/649 (44%), Gaps = 58/649 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V V+V + D NDN P FV NL Y +++ +A+ + I KV AVD D G NG V Y L++
Sbjct: 785 VTVQVQVEDVNDNAPEFV--NLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQ 842
Query: 502 TSNLTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
F++NP TG +++ ES + + L + A+D P R L V +
Sbjct: 843 QHR-----NFQMNPVTGELTLKKAFESDLSNAEYKLVLVATDGGFPPLSREVELPVTVV- 896
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
NK +P F Y V +V + TS+ I + E V + ++ G +
Sbjct: 897 -------NKA-MPVFDKPFYGVTVREDVAVSTSILGINASSP-EGQIVIFTIIDG-DPSF 946
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F + +G I+V+ L Y A + V V+DVND +
Sbjct: 947 QFDIGFDTGTISVIYPLDYETTQYYRLTVKATDTQTGAKSEVDVDVVVLDVNDNAPLFQN 1006
Query: 679 GAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDG 736
++S ++ EN G + ++F + S N + + L ++ + TD I + G
Sbjct: 1007 TSYSSVL---PENVMIGTTVLKVFAQDQDS-EKNAIVSYQIL-SDIYNSTDYFHIDSSSG 1061
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
IF + LD E + V A + G + + VT+ + D NDNPP F YE F+
Sbjct: 1062 LIFMARRLDYELVQRHNFIVRAT-DSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFV 1120
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDR 855
S++ ++A+DAD Y++ + M F ++ +TGV++ + + +
Sbjct: 1121 ---SELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPDTGVLR-LSNKRRQ 1176
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH-RETKLNGTA 914
K+ Y+L++ D G ++ A++I+ + N P F+Q R + E + N
Sbjct: 1177 GMKLSYQLNVSVSD-GVFTNTAQVIVQVLGANLYSPVFSQ-------RFYLAEVQENAPP 1228
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI-IKLNALDLDSGLNGQIRYEFNSE 973
G +I+V + F + + P+ T+ +++ A D DSGL GQI Y F ++
Sbjct: 1229 GSKVIQV---SLFFHSNTLIRMCPAVQPLKPLECTMTLQVRATDEDSGLFGQITYSFVND 1285
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRV 1033
+ +K + DA + E+ + R P + L + ALDGG SVRV
Sbjct: 1286 --LGKTKFAVDAAGI---ISTLEK-----LDRENPLYKDMVLTVMALDGGGRASFCSVRV 1335
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
+ D ND+ P F+ Y +++ ++ ++ A+D D G N +TY
Sbjct: 1336 ILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNGRITY 1384
Score = 125 bits (301), Expect = 1e-26
Identities = 126/468 (26%), Positives = 209/468 (44%), Gaps = 31/468 (6%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+ ++ V++EV +LD NDNNP+F +N Y ++ +GT + +V+A+DPD G NG V Y
Sbjct: 1541 EAVTTVDLEVKILDVNDNNPLF-ETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY 1599
Query: 498 DLQRTSN--LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+S+ +T +S F I+ TG ++ E + E S VV
Sbjct: 1600 VEAASSDGPITSSSVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVV 1659
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQND-VSYDLLH 612
TI V+ + P P F Y V + +G V ++ + D +QN VS+ +
Sbjct: 1660 TIAVS--DCNDNP--PRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISG 1715
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-TNATVHVVDVND 671
G GV F + G V +R D+ + + + L + T V V+D ND
Sbjct: 1716 GNPRGV-FGLAPVQGEWKVYVS-GLLDREQQDWYLLNITASDGLYVAHTAVEVTVMDAND 1773
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
R + + +S ++ I + T+ S + +++ + V D
Sbjct: 1774 NRPICNQAVYSASF--PEDIPVNKGILTVAATDADS---GSSAEIQYSLFG-IGVEDFYM 1827
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A G + T +DRE Y++ A G+ + +++ + D NDN P F
Sbjct: 1828 DANTGELRTATIMDRETTPSYKLIAQATDGGGLFCRS---DISLKVLDVNDNAPTFSSPH 1884
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + EN+ + ++A+D DEG N +YTL E+F +D +G+V +
Sbjct: 1885 YLASVYENAAPKALLTR---LQASDPDEGLNRTLVYTL-DSIDELFSIDPVSGMV-VLEK 1939
Query: 852 SLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
SLDRE + Y+L + A D G LS++ L I++ D NDN P F +
Sbjct: 1940 SLDRESQDSYRLRVQATDQAGQRGALSTQVNLTILVLDVNDNAPVFQR 1987
Score = 124 bits (299), Expect = 2e-26
Identities = 121/472 (25%), Positives = 209/472 (44%), Gaps = 37/472 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
SF +V V L D NDN P F Y S+K+N G+++ +++A DPD G NG + Y L
Sbjct: 1329 SFCSVRVILADENDNPPRFRAVE-YRMSIKANVAKGSLVTQIQASDPDAGSNGRITYSLY 1387
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPI--LEGR-HALFVEASDQPANPSERRYSLAVVTI 557
+ L++ +++ + +S + L+G + FV+A+D + S ++SL I
Sbjct: 1388 SEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATD---SGSPAKHSLVSAFI 1444
Query: 558 EVTRGTKGNKPD--IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHG 613
V PD +P F Y F + + +GT++G + + V +++
Sbjct: 1445 HVV------PPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGFFTAVVGEMVDS 1498
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT--NATVHVVDVND 671
+G F V+ SG+I + L ++ F+ + VT + V ++DVND
Sbjct: 1499 -NQGGTFLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDLEVKILDVND 1557
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDD 729
+ + + ++ G + Q+ + +G G V ++ A D +T
Sbjct: 1558 NNPLFETNTYVATV--MEGMPIGTRVVQV--RALDPDWG-ANGQVCYVEAASSDGPITSS 1612
Query: 730 IAIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
A D G I T +D E Y V+A + S + VTI + D NDNPP
Sbjct: 1613 SVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPR 1672
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGKEMFDVDENTG 844
FE Y G + E+ +G + ++K +D D + + Y G + +F + G
Sbjct: 1673 FERELYRGAVKESDSLGEVVA---VLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQG 1729
Query: 845 VVK-FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
K ++ LDRE++ Y L++ A D G + + + + D NDN+P NQ
Sbjct: 1730 EWKVYVSGLLDREQQDWYLLNITASD-GLYVAHTAVEVTVMDANDNRPICNQ 1780
Score = 113 bits (273), Expect = 3e-23
Identities = 91/293 (31%), Positives = 137/293 (46%), Gaps = 26/293 (8%)
Query: 929 LDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F +PE++ +GT ++++ A +D GLN +I Y S ++L
Sbjct: 1976 LDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEISYRIRSG-----NEL 2030
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKD 1037
F I+ G + VA L E ++ L I A DGGN L+ V + + D
Sbjct: 2031 GK--------FNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSSATVVTIDLMD 2082
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND+ P F + YN V E +++ +V A D D N +TY I D + F I P
Sbjct: 2083 VNDNAPTFSQDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITYSILKGDRNNHFWIDP 2142
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
+TG+L VN LDRE +Y L+V A D+G D+NDNSP F +
Sbjct: 2143 VTGILKVNKRLDRELVSRYSLSVQAFDSG-SPAMSSTVTLNIDISDINDNSPVFTPPNST 2201
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+ P A L S + +P + ++ N G+T+ K+ +D D NG
Sbjct: 2202 AIIQVP-APALLLVFVRSYISLPPPLSHLQLNQAAGSTLLKLSVSDKDSPKNG 2253
Score = 111 bits (266), Expect = 2e-22
Identities = 117/447 (26%), Positives = 192/447 (42%), Gaps = 28/447 (6%)
Query: 459 FVPS---NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
FVPS Y F++ + VGT +G V + P GQ G + + F ++
Sbjct: 1452 FVPSFSQPQYSFTIPEDTVVGTALGSVY-MGP--GQTGFFTAVVGEMVDSNQGGTFLVDR 1508
Query: 516 NTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMG 575
+G + +++ P+ ++F + A + R AV T+++ + P F
Sbjct: 1509 ESGLIRLSK-PLDYEEVSIF---RFKVAVTTRRDLIEAVTTVDLEVKILDVNDNNPLFET 1564
Query: 576 APYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVP----FAVEERSGVI 629
Y V + IGT V Q+R D V Y + + FA++ ++G I
Sbjct: 1565 NTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGPITSSSVFAIDSKTGWI 1624
Query: 630 TVVDDLSRYNRPMYDFEAVA--LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
T V ++ Y FE VA L E +LS T T+ V D ND + + +
Sbjct: 1625 TTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELYRGAV-- 1682
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
+ +S G + + ++ N + N + V + + ++ LDRE
Sbjct: 1683 KESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVSGLLDRE 1742
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
++D Y + + A + G+ +VT+ D NDN P+ A Y E+ + I
Sbjct: 1743 QQDWYLLNITA--SDGLYVAHTAVEVTVM--DANDNRPICNQAVYSASFPEDIPVNKGIL 1798
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
+ ATDAD G++A Y+LFG G E F +D NTG ++ +DRE YKL A
Sbjct: 1799 T---VAATDADSGSSAEIQYSLFGIGVEDFYMDANTGELR-TATIMDRETTPSYKLIAQA 1854
Query: 868 RDTGGLSSEAELIIMIGDENDNKPEFN 894
D GGL +++ + + D NDN P F+
Sbjct: 1855 TDGGGLFCRSDISLKVLDVNDNAPTFS 1881
Score = 111 bits (266), Expect = 2e-22
Identities = 161/669 (24%), Positives = 271/669 (40%), Gaps = 67/669 (10%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
NI D ++ VEVT++DANDN P+ +Y S + V I V A D D G
Sbjct: 1750 NITASDGLYVAHTAVEVTVMDANDNRPI-CNQAVYSASFPEDIPVNKGILTVAATDADSG 1808
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSER 548
+ + Y L F ++ NTG + A E + L +A+D
Sbjct: 1809 SSAEIQYSLFGIG----VEDFYMDANTGELRTATIMDRETTPSYKLIAQATDGGGLFCRS 1864
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVS 607
SL V+ + T + P ++ + YE N + +++ +D E N
Sbjct: 1865 DISLKVLDVNDNAPTFSS----PHYLASVYE-----NAAPKALLTRLQASDPDEGLNRTL 1915
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ---ENANLSIVTNATV 664
L +E F+++ SG++ + L R ++ Y A + LS N T+
Sbjct: 1916 VYTLDSIDE--LFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGALSTQVNLTI 1973
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V+DVND V + + + ++ + G + ++ T S+ + + I +
Sbjct: 1974 LVLDVNDNAPVFQRRDYGVTV--PEDVAVGTEVLRVLAT---SVDIGLNAEISYRIRSGN 2028
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDN 783
++ G+IF LD E Y +T+ A + +S A + VTI + D NDN
Sbjct: 2029 ELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSSATV--VTIDLMDVNDN 2086
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDEN 842
P F Y + E++ +G +M + A D D N Y++ G+ F +D
Sbjct: 2087 APTFSQDIYNVLVSEDASVG---QMVTRVSAEDLDSQGNGRITYSILKGDRNNHFWIDPV 2143
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENS 900
TG++K + LDRE Y LS+ A D+G +SS L I I D NDN P F +
Sbjct: 2144 TGILK-VNKRLDRELVSRYSLSVQAFDSGSPAMSSTVTLNIDISDINDNSPVFTPPNSTA 2202
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
+++ L ++ V+ + PL + N G+T++KL+ D DS
Sbjct: 2203 IIQVPAPALL-------LVFVRSY------ISLPPPLSHLQLNQAAGSTLLKLSVSDKDS 2249
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNIS 1018
NG PP + + +F +++ G + R PE+ EF L I
Sbjct: 2250 PKNG------------PPFDFRIVSGNEENFFSLDQA-GTLKSNRVFDPEAPREFTLEIQ 2296
Query: 1019 ALDGGNLNDNISVRVFVKDV--NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
D G S VF++ + + + P+ + + +G++ ATD D
Sbjct: 2297 VSDSGKPRLAASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGGPIGRIYATDRDPND 2356
Query: 1077 NANLTYFIQ 1085
+ T +Q
Sbjct: 2357 VLSFTQKLQ 2365
Score = 105 bits (252), Expect = 9e-21
Identities = 122/463 (26%), Positives = 189/463 (40%), Gaps = 48/463 (10%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
PE+IP+ I+ + A D DSG + +I+Y + + + A+ E++ +++
Sbjct: 1788 PEDIPVNKGILTVAATDADSGSSAEIQYSLFG-IGVEDFYMDANTGELRTATIMD----- 1841
Query: 1001 VIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
R P ++L A DGG L + + V DVND+ P F Y +V E
Sbjct: 1842 ----RETTPS--YKLIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAP 1895
Query: 1061 RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
+ +L ++ A+D D G N L Y + D +L F I P++G++ + LDRE++D Y L V
Sbjct: 1896 KALLTRLQASDPDEGLNRTLVYTLDSID-EL-FSIDPVSGMVVLEKSLDRESQDSYRLRV 1953
Query: 1121 VARDN-GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
A D G DVNDN+P F D + A + +
Sbjct: 1954 QATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVD 2013
Query: 1180 PVYKATIEENAPIGTTVAKVFANDTD----FIGNGNGL-ILYSLPQRKNQQNLGLPSLSS 1234
A I G + K F DT+ F+ + + + G P LSS
Sbjct: 2014 IGLNAEISYRIRSGNELGK-FNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSS 2072
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRY 1292
++ + + DV D P F Y + + E+ V V VS + N ++ Y
Sbjct: 2073 ATVVTIDLMDVNDNA-----PTFSQDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITY 2127
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
IL D F IDP G L + + DRE+ Y + V+A + P M
Sbjct: 2128 SILKG---DRNNHFWIDPVTGILKVNKRLDRELVSRYSLSVQA----FDSGSPAM----- 2175
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTA 1395
V + + I D+NDNSP FT N + +P A
Sbjct: 2176 --------SSTVTLNIDISDINDNSPVFTPPNSTAIIQVPAPA 2210
Score = 102 bits (244), Expect = 9e-20
Identities = 130/469 (27%), Positives = 204/469 (43%), Gaps = 41/469 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLY 497
L S V + + D NDN P F LY ++K + +G V+ +K D D QN +V +
Sbjct: 1653 LSSTTVVTIAVSDCNDNPPRF-ERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSF 1711
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ + + F + P G V S +L+ + + S+ Y +A +
Sbjct: 1712 YISGGNPRGV---FGLAPVQGEWKVYVSGLLDREQQDWYLLN---ITASDGLY-VAHTAV 1764
Query: 558 EVT-RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLH-G 613
EVT N+P A Y ++ + + + DA + ++ Y L G
Sbjct: 1765 EVTVMDANDNRPICNQ---AVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFGIG 1821
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
E+ F ++ +G + + R P Y A A + L ++ ++ V+DVND
Sbjct: 1822 VED---FYMDANTGELRTATIMDRETTPSYKLIAQAT-DGGGLFCRSDISLKVLDVNDNA 1877
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
H + V EN+A A+ T + + + G R L+ + + +I
Sbjct: 1878 PTF-SSPH--YLASVYENAAPKAL----LTRLQASDPD-EGLNRTLVYTLDSIDELFSID 1929
Query: 734 E-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV--TIYIEDENDNPPVFEHA 790
G + +K LDRE +D YR+ V A G GA QV TI + D NDN PVF+
Sbjct: 1930 PVSGMVVLEKSLDRESQDSYRLRVQATDQAGQ-RGALSTQVNLTILVLDVNDNAPVFQRR 1988
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--FDVDENTGVVKF 848
Y + E+ +GTE+ + AT D G NA Y + G E+ F++D N G + F
Sbjct: 1989 DYGVTVPEDVAVGTEVLR---VLATSVDIGLNAEISYRI-RSGNELGKFNIDTNLGSI-F 2043
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ D LD E Y L++ A D G LSS + I + D NDN P F+Q
Sbjct: 2044 VADDLDFEVCKDYYLTIEAWDGGNPPLSSATVVTIDLMDVNDNAPTFSQ 2092
Score = 101 bits (243), Expect = 1e-19
Identities = 118/478 (24%), Positives = 204/478 (42%), Gaps = 42/478 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ D + V + + D NDN PVF Y+ S+ + V + +V+A D D +
Sbjct: 146 VQVTDGTNFATAQVFIRVQDGNDNPPVF-SQPAYDVSVSEDIPVDMELVRVRASDMD--E 202
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERR 549
+ Y + + + F++NP TG V + E R H L + DQ P R
Sbjct: 203 RARLSYSIYGSVDPASMRLFRVNPGTGIVYTTDRLDYEARTQHILTIMVKDQEF-PFNRD 261
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
+ +V +E + +IP F Y+ + GTSV Q+ D + N ++
Sbjct: 262 LARILVAVE------DSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALD--KDNGINGQ 313
Query: 610 LLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
L + E G F ++ +G+I + L + Y V + ++ ++ A+V +
Sbjct: 314 LTYTIEAGNTGSVFGIDAATGLIFIARALDLTSVGFYTL-TVRVSDSGFPPLMATASVRI 372
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
++L SP F KE A T+++++ + + I+ D
Sbjct: 373 -------SLMLSDYSSPK-FSQKEYQAEVLTTG---THVATVTALSRSALFYDISRGNDD 421
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G I T+K LD E+ Y + V A + + VT+ + D NDN PV
Sbjct: 422 LCFYINHHTGVINTRKLLDFEQTPSYFLVVHALSMTRMEAST---TVTVQVGDVNDNSPV 478
Query: 787 FEHATYEGFIMENSKIGTEIKMDN----IIKATDADEGTNALFMYTLFGEGKEM-FDVDE 841
F+ Y G I E + + + + D+ +I+ATD D NAL ++ + E M F +D
Sbjct: 479 FQQLRYVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDETARMFFSIDS 538
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTG----GLSSEAELIIMIGDENDNKPEFNQ 895
TG ++ I SLD E + + RD+G S A++ I + + ND+ P+ +Q
Sbjct: 539 GTGSIRTIA-SLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQ 595
Score = 101 bits (241), Expect = 2e-19
Identities = 119/494 (24%), Positives = 209/494 (42%), Gaps = 57/494 (11%)
Query: 929 LDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ PLF + E +PIGT ++++ ALD D G NGQ+ Y E +
Sbjct: 1553 LDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY---VEAASSDGPI 1609
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG---NLNDNISVRVFVK 1036
++ ++ F I+ + G + + E S + + A D G +L+ V + V
Sbjct: 1610 TSSSV-----FAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVS 1664
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEI 1095
D ND+ P F++ Y V+E+ V+ + +D D QN ++++I + F +
Sbjct: 1665 DCNDNPPRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGL 1724
Query: 1096 SPLTG--VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+P+ G + V+G LDRE +D Y+L + A D D NDN P
Sbjct: 1725 APVQGEWKVYVSGLLDREQQDWYLLNITASDG----LYVAHTAVEVTVMDANDNRP--IC 1778
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
+ PE ++ + ++ + A +A I ++ + D N L
Sbjct: 1779 NQAVYSASFPEDIPVN----KGILTVAATDADSGSSAEIQYSLFGIGVEDFYMDANTGEL 1834
Query: 1214 ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEENVN 1271
++ R+ + L + ++ + +D+ +V +++D P F S +Y + EN
Sbjct: 1835 RTATIMDRETTPSYKLIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAA 1894
Query: 1272 APVELVSLNLTEHYENF-KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
L L ++ E + Y L+ D F IDP +G + L +S DRE +D+Y
Sbjct: 1895 PKALLTRLQASDPDEGLNRTLVYTLDSID----ELFSIDPVSGMVVLEKSLDRESQDSYR 1950
Query: 1331 VIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA 1390
+ V+A Q R G V + + + DVNDN+P F R
Sbjct: 1951 LRVQATDQAGQR---------------GALSTQVNLTILVLDVNDNAPVFQ--RRDYGVT 1993
Query: 1391 IPTTAPFGYQVMQL 1404
+P G +V+++
Sbjct: 1994 VPEDVAVGTEVLRV 2007
Score = 99 bits (238), Expect = 5e-19
Identities = 153/603 (25%), Positives = 253/603 (41%), Gaps = 87/603 (14%)
Query: 902 VRIHRETKLNGTAGFTI-IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
V + RE ++ A T+ ++V+ N A + L + + + I K++A+D D+
Sbjct: 771 VEVSREDEILRVARVTVQVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDT 830
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE---SEFRLNI 1017
G+NG++ Y + R F +N G + + ++ + +E++L +
Sbjct: 831 GVNGEVSYSLKQQ---------------HRNFQMNPVTGELTLKKAFESDLSNAEYKLVL 875
Query: 1018 SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQ 1076
A DGG + V + V VN PVF K +Y V E+ + +LG ++A+ + GQ
Sbjct: 876 VATDGGFPPLSREVELPVTVVNKAMPVFDKPFYGVTVREDVAVSTSILG-INASSPE-GQ 933
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
T I D F+I TG +SV LD ET Y LTV A D
Sbjct: 934 IVIFT--IIDGDPSFQFDIGFDTGTISVIYPLDYETTQYYRLTVKATD--TQTGAKSEVD 989
Query: 1137 XXXXXXDVNDNSPKFY--AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
DVNDN+P F ++ +L PE + +V+ + E+NA +
Sbjct: 990 VDVVVLDVNDNAPLFQNTSYSSVL----PENVMIGT----TVLKVFAQDQDSEKNAIVSY 1041
Query: 1195 TVAKVFANDTDF--IGNGNGLIL------YSLPQRKN----QQNLGLPSLSSTAILMVTV 1242
+ N TD+ I + +GLI Y L QR N + G P+LSS + VTV
Sbjct: 1042 QILSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPTLSSDVSVTVTV 1101
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVNAP--VELVSLNLTEHYENFKMRYYILNENDT 1300
D D + P F YE + E V V + + + ++RY I++ N+
Sbjct: 1102 TDTND-----NPPNFSQTLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNE- 1155
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
R TF+++P G L L + +K +Y++ V V +G+
Sbjct: 1156 --RMTFLMEPDTGVLRLSNKRRQGMKLSYQLNV--------------------SVSDGVF 1193
Query: 1361 KYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRA 1420
+V+V++ N SP F+ R + + AP G +V+Q+ H T R A
Sbjct: 1194 TNTAQVIVQVLGANLYSPVFS--QRFYLAEVQENAPPGSKVIQV-SLFFHSNTLIRMCPA 1250
Query: 1421 DTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQA-PRFAIDPVSGTVRVVAAL 1479
+ + L +ATD D G+ I Y +N+ +FA+D +G + + L
Sbjct: 1251 ----VQPLKPLECTMTLQVRATDEDSGLFGQITYSFVNDLGKTKFAVD-AAGIISTLEKL 1305
Query: 1480 ARD 1482
R+
Sbjct: 1306 DRE 1308
Score = 93.1 bits (221), Expect = 5e-17
Identities = 91/327 (27%), Positives = 146/327 (44%), Gaps = 30/327 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+++ + DVNDN P F Y +V E KA + + P + T+ L
Sbjct: 1866 ISLKVLDVNDNAPTFSSPHYLASVYE--NAAPKALLTRLQASDPDEGLNRTLVYTLDSID 1923
Query: 143 DIRAFDR-------DKPNTPNSDVHYSI-VSGNDD-GHFALESSHKPVLLLRKVLDYDAG 193
++ + D +K S Y + V D G S+ + +L VLD +
Sbjct: 1924 ELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGALSTQVNLTIL--VLDVNDN 1981
Query: 194 DKEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
FQ V + + E+L + A D+G+ A + Y + SGN+ F++D+
Sbjct: 1982 APVFQRRDYGVTVPEDVAVGTEVL---RVLATSVDIGLNAEISYRIRSGNELGKFNIDTN 2038
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
GS+F+ +LD + + L ++A NP ++ V I+L+D+NDN P F D
Sbjct: 2039 LGSIFVADDLDFEV-----CKDYYLTIEAWDGGNPPLSSATVVTIDLMDVNDNAPTFSQD 2093
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQT 367
YN+ + E+ G V +V A D D NG TY + D F IDP +G L V +
Sbjct: 2094 IYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITYSILKGDRNNHFWIDPVTGILKVNKR- 2152
Query: 368 VLDREAHSSLRMKVYAKET-NPSVVGT 393
LDRE S + V A ++ +P++ T
Sbjct: 2153 -LDRELVSRYSLSVQAFDSGSPAMSST 2178
Score = 79.0 bits (186), Expect = 9e-13
Identities = 71/236 (30%), Positives = 102/236 (43%), Gaps = 29/236 (12%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P F P EN + +L A D D GLN + Y +S
Sbjct: 1871 LDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDPDEGLNRTLVYTLDS--------- 1921
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDG----GNLNDNISVRVFV 1035
+ F I+ G V++ +SL ES+ +RL + A D G L+ +++ + V
Sbjct: 1922 ------IDELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGALSTQVNLTILV 1975
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
DVND+ PVF++ Y V E + +V AT D G NA ++Y I+ + F I
Sbjct: 1976 LDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEISYRIRSGNELGKFNI 2035
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
G + V +LD E Y LT+ A D G DVNDN+P F
Sbjct: 2036 DTNLGSIFVADDLDFEVCKDYYLTIEAWDGG-NPPLSSATVVTIDLMDVNDNAPTF 2090
Score = 77.4 bits (182), Expect = 3e-12
Identities = 55/179 (30%), Positives = 90/179 (50%), Gaps = 17/179 (9%)
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
A D+ D+ + GT+ KPLD E + VY MTV + G + QV I ++D
Sbjct: 112 AGSFDMQFDLQVGV-GTLIVAKPLDAEVQSVYNMTV--QVTDG--TNFATAQVFIRVQDG 166
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEM 836
NDNPPVF Y+ + E+ + E+ ++A+D DE A Y+++G +
Sbjct: 167 NDNPPVFSQPAYDVSVSEDIPVDMELVR---VRASDMDE--RARLSYSIYGSVDPASMRL 221
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEF 893
F V+ TG+V + D LD E + + L+++ +D + A +++ + D NDN P F
Sbjct: 222 FRVNPGTGIV-YTTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYF 279
Score = 76.6 bits (180), Expect = 5e-12
Identities = 109/415 (26%), Positives = 172/415 (41%), Gaps = 59/415 (14%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F IN G + + L E + L + AL + + +V V V DVND+ PVF++
Sbjct: 424 FYINHHTGVINTRKLLDFEQTPSYFLVVHALSMTRMEASTTVTVQVGDVNDNSPVFQQLR 483
Query: 1050 YNFNVEEAQYTRRV-LGK------VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
Y + EA V LG + ATD D NA L + I + F I TG +
Sbjct: 484 YVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDETARMFFSIDSGTGSI 543
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXX-XXXXXXXXDVNDNSPKF---------- 1151
LD E ++ V RD+G ++ND+ PK
Sbjct: 544 RTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLL 603
Query: 1152 ---YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG 1208
YA E+L+ + + D S+ +SV VY + +E N +V + T +
Sbjct: 604 LPTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVY-SLVESNVE-NFSVDRFSGTVT--VA 659
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
N N L + + Q + + T++ VTV V ++ ++ S Y I E
Sbjct: 660 NPN------LNKDRYQFTVKVWDGRFTSMASVTVL-VRKAIDSG--LLYTSPEYFASIPE 710
Query: 1269 NVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKD 1327
N++ + ++ H N +RY +LN + FVI P G + P DRE+ D
Sbjct: 711 NISNVTVVTVVSTIGHRLNEPLRYTLLNAGER-----FVIRPTCGVVLTTGVPFDRELAD 765
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
+YE++V R ED + + + V V V+++DVNDN+P+F N
Sbjct: 766 SYELVVEVSR---------------EDEILRVAR--VTVQVQVEDVNDNAPEFVN 803
Score = 75.8 bits (178), Expect = 9e-12
Identities = 49/160 (30%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA-RV 292
E++ N F +D +G + L K LD + + + F +V + + ++ +
Sbjct: 1494 EMVDSNQGGTFLVDRESGLIRLSKPLDYE-----EVSIFRFKVAVTTRRDLIEAVTTVDL 1548
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY----QLDDP 348
E+++LD+NDN P FE + Y +++E +P G V+QV A D D G NG+ Y D P
Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGP 1608
Query: 349 ---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F+ID ++GW+T ++ +D EA SS +V A +
Sbjct: 1609 ITSSSVFAIDSKTGWITTVSE--MDHEACSSYSFEVVASD 1646
Score = 68.9 bits (161), Expect = 1e-09
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 10/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A ++Y L G + F +D+ G L +D + ++ L Q
Sbjct: 1800 VAATDADSGSSAEIQYSLF-GIGVEDFYMDANTGELRTATIMDRET-----TPSYKLIAQ 1853
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ ++ + +++LD+NDN P F Y S+ EN + ++ A+D D+G
Sbjct: 1854 ATDGGGLF--CRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDPDEGL 1911
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y LD FSIDP SG + + LDRE+ S R++V A +
Sbjct: 1912 NRTLVYTLDSIDELFSIDPVSGMVVLEKS--LDRESQDSYRLRVQATD 1957
Score = 68.5 bits (160), Expect = 1e-09
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 8/170 (4%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G ++T LD E R + +T++ + + + + ++ + +ED NDN P F Y+
Sbjct: 229 GIVYTTDRLDYEARTQHILTIMVKDQEFPFN-RDLARILVAVEDSNDNIPYFTSTVYDAV 287
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLD 854
E+S GT + + A D D G N YT+ G +F +D TG++ FI +LD
Sbjct: 288 AYESSPFGTSVLQ---VTALDKDNGINGQLTYTIEAGNTGSVFGIDAATGLI-FIARALD 343
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
Y L++ D+G L + A + I + + + P+F+Q E ++V
Sbjct: 344 LTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSPKFSQKEYQAEV 393
Score = 65.7 bits (153), Expect = 9e-09
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Query: 224 DLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
D+ A L Y + D +LF ++ G ++ LD +A +L +
Sbjct: 199 DMDERARLSYSIYGSVDPASMRLFRVNPGTGIVYTTDRLDYEAR-----TQHILTIMVKD 253
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
P AR+ + + D NDN+P F Y+ E+ P G SVLQV A DKD G NG+
Sbjct: 254 QEFPFNRDLARILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQ 313
Query: 341 FTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
TY ++ + F ID +G + + L +L ++V
Sbjct: 314 LTYTIEAGNTGSVFGIDAATGLIFIARALDLTSVGFYTLTVRV 356
Score = 64.5 bits (150), Expect = 2e-08
Identities = 77/297 (25%), Positives = 130/297 (43%), Gaps = 34/297 (11%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGL 138
A ++V V +EDVNDN P F++ PY+ V ++ E A IF ++ + + V L
Sbjct: 783 ARVTVQVQVEDVNDNAPEFVNLPYYAAV-QVDAEPESA-IFKVSAVDRDTGVNGEVSYSL 840
Query: 139 TIFKDIRAFDRDKPN----------TPNSDVHYSIVSGNDDGHFALESSHK--PVLLLRK 186
+ R F + + S+ Y +V DG F S PV ++ K
Sbjct: 841 K--QQHRNFQMNPVTGELTLKKAFESDLSNAEYKLVLVATDGGFPPLSREVELPVTVVNK 898
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
+ DK F G + +++ I I+ G + + +I G+ F +
Sbjct: 899 AMP--VFDKPFY------GVTVREDVAVSTSILGINASSPEGQIVIFTIIDGDPSFQFDI 950
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G++ + LD + + L V+A+ K+ + V++ +LD+NDN P F
Sbjct: 951 GFDTGTISVIYPLDYET-----TQYYRLTVKATDTQTGAKS-EVDVDVVVLDVNDNAPLF 1004
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGA---FSIDPRSG 359
+ Y+ + EN+ G +VL+V A D+D +N +YQ L D + F ID SG
Sbjct: 1005 QNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDIYNSTDYFHIDSSSG 1061
Score = 64.1 bits (149), Expect = 3e-08
Identities = 43/128 (33%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G+ + Y ++ + F++D+ LEK LD E+ L + VL V
Sbjct: 1265 VRATDEDSGLFGQITYSFVNDLGKTKFAVDAAGIISTLEK---LDRENPLYKD-MVLTVM 1320
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A L+ + + V + L D NDN P F Y +SI N+ G V Q+ A+D D G
Sbjct: 1321 A--LDGGGRASFCSVRVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGS 1378
Query: 338 NGEFTYQL 345
NG TY L
Sbjct: 1379 NGRITYSL 1386
Score = 63.3 bits (147), Expect = 5e-08
Identities = 83/365 (22%), Positives = 145/365 (39%), Gaps = 35/365 (9%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLND---NISVRVFVKDVNDHFPVFK 1046
F+++ G + +++ L E S FR ++ +L + + + V + DVND+ P+F+
Sbjct: 1504 FLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDLEVKILDVNDNNPLFE 1563
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP------FEISPLTG 1100
Y V E + +V A D D+G N + Y ++ + +D P F I TG
Sbjct: 1564 TNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY-VEAASSDGPITSSSVFAIDSKTG 1622
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
++ E+D E Y VVA D G D NDN P+F EL
Sbjct: 1623 WITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFER--ELYRG 1680
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA--NDTDFIG----NGNGLI 1214
E+D L ++ V K + + V+ + N G G +
Sbjct: 1681 AVKESDSLGE-------VVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKV 1733
Query: 1215 LYSLPQRKNQQNLGLPSLSSTAILMV--TVADVPDEVEMSDKPVFISRYYELEIEEN--V 1270
S + QQ+ L +++++ L V T +V ++P+ Y E+ V
Sbjct: 1734 YVSGLLDREQQDWYLLNITASDGLYVAHTAVEVTVMDANDNRPICNQAVYSASFPEDIPV 1793
Query: 1271 NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
N + V+ + + +++Y + D F +D G L DRE +Y+
Sbjct: 1794 NKGILTVAATDADSGSSAEIQYSLFGIGVED----FYMDANTGELRTATIMDRETTPSYK 1849
Query: 1331 VIVRA 1335
+I +A
Sbjct: 1850 LIAQA 1854
Score = 62.9 bits (146), Expect = 7e-08
Identities = 131/655 (20%), Positives = 253/655 (38%), Gaps = 59/655 (9%)
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDEN 842
P +F +Y ++E + + + ++ T + T ++ + G +EMF + +N
Sbjct: 31 PLLFTQRSYNFSVLETAAVAQPV---GVVAIT---QSTTPVWFNIIGGRLAREMFYIPQN 84
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
D+++ + + + G + +L + +G KP +++ +
Sbjct: 85 ACGRNCSLDTVEADDTGAQQHPHINDAAGSFDMQFDLQVGVGTLIVAKPLDAEVQSVYNM 144
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
+ N I V+ N Q + E+IP+ ++++ A D+D
Sbjct: 145 TVQVTDGTNFATAQVFIRVQDGNDNPPVFSQPAYDVSVSEDIPVDMELVRVRASDMDE-- 202
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISAL 1020
+ R ++ + P+ + R F +N G V L E+ + L I
Sbjct: 203 --RARLSYSIYGSVDPASM--------RLFRVNPGTGIVYTTDRLDYEARTQHILTIMVK 252
Query: 1021 DGG-NLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
D N +++ + V V+D ND+ P F T Y+ E+ + +V A D D G N
Sbjct: 253 DQEFPFNRDLARILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGING 312
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
LTY I+ +T F I TG++ + LD + Y LTV D+G
Sbjct: 313 QLTYTIEAGNTGSVFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRI 372
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK 1198
+ +SPKF K +A+ L+ + + A + + +
Sbjct: 373 SLMLS-DYSSPKF-------SQKEYQAEVLTTGTHVATVTALSRSALFYDISRGNDDLCF 424
Query: 1199 VFANDTDFIGNGNGLILYSLPQR-KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
+ T I L P L + + ++ + V V DV D + + +
Sbjct: 425 YINHHTGVINTRKLLDFEQTPSYFLVVHALSMTRMEASTTVTVQVGDVNDNSPVFQQLRY 484
Query: 1258 ISRYYELEIEENV-----NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRN 1312
+ E +V P+ + + ++ ++ N + ++IL+E R F ID
Sbjct: 485 VGTISEAAPVNSVVLGDDGNPLVIQATDMDRNH-NALLVFHILDET---ARMFFSIDSGT 540
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
G++ + S D YE+ Q Y R+ P + D V +++ +
Sbjct: 541 GSIRTIASLD------YEIFSEFFFQVYVRDSGQP--PRSAD-------SPADVFIKVIN 585
Query: 1373 VNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRADTDELVF 1427
+ND+ PK + V +PT A G +V+Q++ A T+ T+++ T +LV+
Sbjct: 586 INDSPPKLSQDTYETVLLLPTYA--GVEVLQVE-ASDPDMTSDFTLKSVTPQLVY 637
Score = 62.9 bits (146), Expect = 7e-08
Identities = 42/135 (31%), Positives = 74/135 (54%), Gaps = 8/135 (5%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
LRY L++ +R F + G + L + D E A+++ L V+ S+ + L+ A+
Sbjct: 732 LRYTLLNAGER--FVIRPTCG-VVLTTGVPFDRE---LADSYELVVEVSREDEILRVARV 785
Query: 291 RVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
V++++ D+NDN PEF + +Y V+ P ++ +V A D+D G NGE +Y L
Sbjct: 786 TVQVQVEDVNDNAPEFVNLPYYAAVQVDAEPES-AIFKVSAVDRDTGVNGEVSYSLKQQH 844
Query: 350 GAFSIDPRSGWLTVR 364
F ++P +G LT++
Sbjct: 845 RNFQMNPVTGELTLK 859
Score = 62.1 bits (144), Expect = 1e-07
Identities = 48/154 (31%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+ + GN R +F L V G + LD E Q + ++L + AS + L A V
Sbjct: 1711 FYISGGNPRGVFGLAPVQGEWKVYVSGLLDRE---QQDWYLLNITAS---DGLYVAHTAV 1764
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA 351
E+ ++D NDN P Y+ S E++P +L V ATD D G + E Y L
Sbjct: 1765 EVTVMDANDNRPICNQAVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFGIGVED 1824
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F +D +G L R T++DRE S ++ A +
Sbjct: 1825 FYMDANTGEL--RTATIMDRETTPSYKLIAQATD 1856
Score = 61.3 bits (142), Expect = 2e-07
Identities = 73/295 (24%), Positives = 120/295 (40%), Gaps = 25/295 (8%)
Query: 27 LNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL-VRIGAG-----LNQISAY 80
LNRT V + SID L D +V D + D +R+ A +S
Sbjct: 1911 LNRTLVYTL--DSIDELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGALSTQ 1968
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGL 138
+++T+ + DVNDN P+F Y VTV E G + L IG + I + G
Sbjct: 1969 VNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEISYRIRSGN 2028
Query: 139 TIFK---DIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY-D 191
+ K D F D + +Y + D G+ L S+ + L V D
Sbjct: 2029 ELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSSATVVTIDLMDVNDNAP 2088
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
++ V+++ + + + + A D D + Y ++ G+ F +D V G
Sbjct: 2089 TFSQDIYNVLVSEDASVGQMVT---RVSAEDLDSQGNGRITYSILKGDRNNHFWIDPVTG 2145
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
L + K LD + + + L VQA +P ++ + I++ D+NDN P F
Sbjct: 2146 ILKVNKRLDREL-----VSRYSLSVQAFDSGSPAMSSTVTLNIDISDINDNSPVF 2195
Score = 60.5 bits (140), Expect = 3e-07
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
Query: 218 IHAIDQDLGVGATLRYELISG--NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A DQD A + Y+++S N F +DS +G +F+ + LD + +Q + F+
Sbjct: 1026 VFAQDQDSEKNAIVSYQILSDIYNSTDYFHIDSSSGLIFMARRLDYEL---VQRHNFI-- 1080
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ +P ++ V + + D NDN P F Y + E P V V A+D D
Sbjct: 1081 VRATDSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDADI 1140
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
+ Y + + + F ++P +G L + N+
Sbjct: 1141 CDAQRLRYSIVSGNERMTFLMEPDTGVLRLSNK 1173
Score = 57.2 bits (132), Expect = 3e-06
Identities = 105/449 (23%), Positives = 176/449 (39%), Gaps = 50/449 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF--IFLIAPIGPSLTIPLTVPRGLT- 139
+ V +ED NDN+P F T Y E +P G L G + + T+ G T
Sbjct: 265 ILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTG 324
Query: 140 -IFKDIRAFDR---DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA--- 192
+F A + S Y++ D F + V + + DY +
Sbjct: 325 SVFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSPKF 384
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
KE+Q ++ +G + + A+ + + L Y++ GND F ++ G
Sbjct: 385 SQKEYQAEVLTTGTHV-------ATVTALSR-----SALFYDISRGNDDLCFYINHHTGV 432
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ K LD + Q ++ L V A + A V +++ D+NDN P F+ Y
Sbjct: 433 INTRKLLDFE-----QTPSYFLVVHALSMTR--MEASTTVTVQVGDVNDNSPVFQQLRYV 485
Query: 313 ISIVENLPNGFSV-------LQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTV 363
+I E P V L + ATD D+ N + + D FSID SG ++
Sbjct: 486 GTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDETARMFFSID--SGTGSI 543
Query: 364 RNQTVLDREAHSSLRMKVYAKETN--PSVVGTFAD-SQRIAKWRRQPLETNAPLEKTTYV 420
R LD E S +VY +++ P + AD ++ P + + +T +
Sbjct: 544 RTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLL 603
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPV-FVPSNLYEFSMKSNAKVGTVI 479
P G + +E D + S + TL V SN+ FS+ + GTV
Sbjct: 604 LPTYAGVEVLQVEASDPDMTS----DFTLKSVTPQLVYSLVESNVENFSVDRFS--GTVT 657
Query: 480 GKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
++ D Q + ++D + TS ++T
Sbjct: 658 VANPNLNKDRYQFTVKVWDGRFTSMASVT 686
Score = 56.8 bits (131), Expect = 4e-06
Identities = 57/193 (29%), Positives = 91/193 (47%), Gaps = 14/193 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V+V+V +LD NDN P+F + Y + N +GT + KV A D D +N +V Y +
Sbjct: 986 SEVDVDVVVLDVNDNAPLF-QNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQI- 1043
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ T F I+ ++G + +A E RH V A+D +P+ S VT+
Sbjct: 1044 LSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRATDS-GDPT--LSSDVSVTVT 1100
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEE 616
VT T N P+F YE +V V ++ +DA + + Y ++ G E
Sbjct: 1101 VT-DTNDNP---PNFSQTLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSG-NE 1155
Query: 617 GVPFAVEERSGVI 629
+ F +E +GV+
Sbjct: 1156 RMTFLMEPDTGVL 1168
Score = 55.2 bits (127), Expect = 1e-05
Identities = 94/386 (24%), Positives = 150/386 (38%), Gaps = 43/386 (11%)
Query: 1005 RSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
R L E + +S D ++V+V V+DVND+ P F Y V+ +
Sbjct: 761 RELADSYELVVEVSREDEILRVARVTVQVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAI 820
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED-KYILTVVAR 1123
KV A D D G N ++Y ++ + F+++P+TG L++ + + + +Y L +VA
Sbjct: 821 FKVSAVDRDTGVNGEVSYSLKQQHRN--FQMNPVTGELTLKKAFESDLSNAEYKLVLVAT 878
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D G VN P FD+ D S ++ +
Sbjct: 879 DGGFPPLSREVELPVTV---VNKAMP---VFDKPFYGVTVREDVA-----VSTSILGINA 927
Query: 1184 ATIEENAPIGTTV--AKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVT 1241
++ E I T + F D F G ++Y L Q + T +
Sbjct: 928 SSPEGQIVIFTIIDGDPSFQFDIGF-DTGTISVIYPLDYETTQYYRLTVKATDTQTGAKS 986
Query: 1242 VADVPDEV-EMSDK-PVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNE 1297
DV V +++D P+F + Y + ENV V V + +N + Y IL++
Sbjct: 987 EVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSD 1046
Query: 1298 --NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDV 1355
N TD F ID +G +++ R D E+ + IVR A D
Sbjct: 1047 IYNSTDY---FHIDSSSGLIFMARRLDYELVQRHNFIVR-----------------ATDS 1086
Query: 1356 LEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ DV V V + D NDN P F+
Sbjct: 1087 GDPTLSSDVSVTVTVTDTNDNPPNFS 1112
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
G + + N T A+ G I T + LDRE +Y+ V+ A V
Sbjct: 1276 GQITYSFVNDLGKTK-FAVDAAGIISTLEKLDREN-PLYKDMVLTVMALDGGGRASFCSV 1333
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+ + DENDNPP F Y I N G+ + I+A+D D G+N Y+L+ E
Sbjct: 1334 RVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQ---IQASDPDAGSNGRITYSLYSEA 1390
Query: 834 K-EMFDVDE 841
+ + DV E
Sbjct: 1391 RLSLVDVLE 1399
Score = 51.2 bits (117), Expect = 2e-04
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 14/177 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGND-----RKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A+D D G + Y + +D +F++DS G + E+D +A +++
Sbjct: 1584 VRALDPDWGANGQVCYVEAASSDGPITSSSVFAIDSKTGWITTVSEMDHEA-----CSSY 1638
Query: 273 VLQVQASQLNNPLKTAQARV-EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+V AS L + V I + D NDN P FE + Y ++ E+ G V + +
Sbjct: 1639 SFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELYRGAVKESDSLGEVVAVLKTS 1698
Query: 332 DK---DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+ DQ F +P+G F + P G V +LDRE + + A +
Sbjct: 1699 DRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVSGLLDREQQDWYLLNITASD 1755
Score = 50.4 bits (115), Expect = 4e-04
Identities = 61/234 (26%), Positives = 103/234 (44%), Gaps = 19/234 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D GV + Y L + F ++ V G L L+K + D L + L +
Sbjct: 823 VSAVDRDTGVNGEVSYSL--KQQHRNFQMNPVTGELTLKKAFESD----LSNAEYKLVLV 876
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P VE+ + +N +P F+ FY +++ E++ S+L + A+ +G+
Sbjct: 877 ATDGGFP--PLSREVELPVTVVNKAMPVFDKPFYGVTVREDVAVSTSILGINAS-SPEGQ 933
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS 397
FT DP F I +G ++V LD E R+ V A +T T A S
Sbjct: 934 IVIFTIIDGDPSFQFDIGFDTGTISVIYP--LDYETTQYYRLTVKATDTQ-----TGAKS 986
Query: 398 QRIAKWRRQPLETNAPL-EKTTY--VFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
+ + NAPL + T+Y V P+ V T ++ + + S N V+
Sbjct: 987 EVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVS 1040
Score = 49.6 bits (113), Expect = 6e-04
Identities = 64/259 (24%), Positives = 96/259 (37%), Gaps = 22/259 (8%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTI 140
+ V V + DVNDN P+F +T Y + E G ++ I
Sbjct: 988 VDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDI 1047
Query: 141 FKDIRAFDRDKPN-----TPNSDV-----HYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
+ F D + D H IV D G L S V + V D
Sbjct: 1048 YNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPTLSSD---VSVTVTVTDT 1104
Query: 191 DAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
+ F Q + A + F + A D D+ LRY ++SGN+R F ++
Sbjct: 1105 NDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPD 1164
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G L L + + + Q N V ++ + T A+V +++L N P F
Sbjct: 1165 TGVLRLSNKRRQGMKLSYQLNVSV--------SDGVFTNTAQVIVQVLGANLYSPVFSQR 1216
Query: 310 FYNISIVENLPNGFSVLQV 328
FY + EN P G V+QV
Sbjct: 1217 FYLAEVQENAPPGSKVIQV 1235
Score = 48.8 bits (111), Expect = 0.001
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 12/137 (8%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG--PSLT 129
+G +S+ +++ + I D+NDN P+F TP + T P +F+ + I P L+
Sbjct: 2170 SGSPAMSSTVTLNIDISDINDNSPVF--TPPNSTAIIQVPAPALLLVFVRSYISLPPPLS 2227
Query: 130 -IPLTVPRGLTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
+ L G T+ K + D+D P N P D + IVSGN++ F+L+ + L +V
Sbjct: 2228 HLQLNQAAGSTLLK-LSVSDKDSPKNGPPFD--FRIVSGNEENFFSLDQA--GTLKSNRV 2282
Query: 188 LDYDAGDKEFQLVIMAS 204
D +A +EF L I S
Sbjct: 2283 FDPEA-PREFTLEIQVS 2298
Score = 47.2 bits (107), Expect = 0.003
Identities = 53/217 (24%), Positives = 87/217 (40%), Gaps = 15/217 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS-ADALEVKRYFVINERH 998
I N+ G+ + ++ A D D+G NG+I Y SE ++LS D LEV R++
Sbjct: 1356 IKANVAKGSLVTQIQASDPDAGSNGRITYSLYSE-----ARLSLVDVLEVSRFY-----S 1405
Query: 999 GHVIVARSLPPESEFRLN--ISALDGGNLNDNISVRVFVKDV-NDHF-PVFKKTWYNFNV 1054
G ++ ++ L+ + A D G+ + V F+ V D F P F + Y+F +
Sbjct: 1406 GWMMTKSNVDHLQGTVLSFFVKATDSGSPAKHSLVSAFIHVVPPDAFVPSFSQPQYSFTI 1465
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E LG V G + + S+ F + +G++ ++ LD E
Sbjct: 1466 PEDTVVGTALGSVYMGPGQTGFFTAVVGEMVDSNQGGTFLVDRESGLIRLSKPLDYEEVS 1525
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ V DVNDN+P F
Sbjct: 1526 IFRFKVAVTTRRDLIEAVTTVDLEVKILDVNDNNPLF 1562
Score = 46.4 bits (105), Expect = 0.006
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F L G+L + K LD + + + + + VQ + N A A+V I + D NDN
Sbjct: 119 FDLQVGVGTLIVAKPLDAEVQ-----SVYNMTVQVTDGTN---FATAQVFIRVQDGNDNP 170
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT-YQLDDPKG--AFSIDPRSGW 360
P F Y++S+ E++P +++V A+D D+ ++ Y DP F ++P +G
Sbjct: 171 PVFSQPAYDVSVSEDIPVDMELVRVRASDMDERARLSYSIYGSVDPASMRLFRVNPGTGI 230
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKE 385
+ ++ LD EA + + + K+
Sbjct: 231 VYTTDR--LDYEARTQHILTIMVKD 253
Score = 46.0 bits (104), Expect = 0.008
Identities = 67/331 (20%), Positives = 125/331 (37%), Gaps = 24/331 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAVEERSGV 628
P F Y+ V ++ + + ++R +D E+ +SY + + F V +G+
Sbjct: 171 PVFSQPAYDVSVSEDIPVDMELVRVRASDMDERARLSYSIYGSVDPASMRLFRVNPGTGI 230
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ D L R + + + + + V V D ND + + +
Sbjct: 231 VYTTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYFTSTVYDAVAY- 289
Query: 688 VKENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
+ + G ++ Q+ T + G NG N V A G IF + LD
Sbjct: 290 -ESSPFGTSVLQV--TALDKDNGINGQLTYTIEAGNTGSVFG--IDAATGLIFIARALDL 344
Query: 747 EKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
Y +TV +++ + ++++ + D + P F Y+ ++ GT
Sbjct: 345 TSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSS--PKFSQKEYQAEVLTT---GTH 399
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ AT +ALF G F ++ +TGV+ LD E+ Y L +
Sbjct: 400 V-------ATVTALSRSALFYDISRGNDDLCFYINHHTGVIN-TRKLLDFEQTPSYFLVV 451
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
A + + + + +GD NDN P F Q+
Sbjct: 452 HALSMTRMEASTTVTVQVGDVNDNSPVFQQL 482
Score = 44.4 bits (100), Expect = 0.024
Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 9/133 (6%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G + ++SGN+ FSLD G+L + D +A F L++Q S P
Sbjct: 2253 GPPFDFRIVSGNEENFFSLDQA-GTLKSNRVFDPEAPRE-----FTLEIQVSDSGKPRLA 2306
Query: 288 AQARVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
A + V + ++ + P ++ + + + P G + ++ ATD+D + FT +L
Sbjct: 2307 ASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGG-PIGRIYATDRDPNDVLSFTQKLQ 2365
Query: 347 DPKGAFSIDPRSG 359
K F I+ + G
Sbjct: 2366 S-KSMFKINRQDG 2377
Score = 37.5 bits (83), Expect = 2.8
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 20 HLFTYRDLNRTHVSVILAQSIDSLVDS-DSPQNVVKFRLGCDFDEGDD--LVRIGAGLNQ 76
H+ T L+R+ + +++ D L + V+ R DF++ LV + +
Sbjct: 399 HVATVTALSRSALFYDISRGNDDLCFYINHHTGVINTRKLLDFEQTPSYFLVVHALSMTR 458
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
+ A +VTV + DVNDN P+F Y T+ E P
Sbjct: 459 MEASTTVTVQVGDVNDNSPVFQQLRYVGTISEAAP 493
Score = 37.1 bits (82), Expect = 3.7
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
VT+ + D+ ++ Y I EN T + + + I N YTL
Sbjct: 685 VTVLVRKAIDSGLLYTSPEYFASIPENISNVTVVTVVSTI-----GHRLNEPLRYTLLNA 739
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL-VARDTGGLS-SEAELIIMIGDENDNK 890
G E F + GVV G DRE Y+L + V+R+ L + + + + D NDN
Sbjct: 740 G-ERFVIRPTCGVVLTTGVPFDRELADSYELVVEVSREDEILRVARVTVQVQVEDVNDNA 798
Query: 891 PEFNQIEENSKVRIHRE 907
PEF + + V++ E
Sbjct: 799 PEFVNLPYYAAVQVDAE 815
Score = 35.9 bits (79), Expect = 8.6
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
+S+ +SVTV + D NDN P F T Y V EL P
Sbjct: 1091 LSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAP 1125
>UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome shotgun
sequence; n=7; Tetraodontidae|Rep: Chromosome 1
SCAF13759, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 3762
Score = 145 bits (352), Expect = 7e-33
Identities = 136/470 (28%), Positives = 219/470 (46%), Gaps = 43/470 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +L N ++P F S +YE + NA+VGT + ++ A+DPD G G V Y +
Sbjct: 2411 VNIDMLSTNKHSPSFKQS-VYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTI----- 2464
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ + K+ ++ V P+ A + A A + + V I +T
Sbjct: 2465 INKLADEKLAIDSDGQMVTTQPLDRENPAQRIIAVKVMAKDGGGKVAFCTVRIILT---- 2520
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYEEGVPFAV 622
++P F + Y+ + S V G+ V I DA E DV+Y + EE +
Sbjct: 2521 DENDNVPQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTVDEA-EEATEDVI 2579
Query: 623 EER--SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKG 679
E +G++TV D L +++F+ A + +L NATV V V V L +
Sbjct: 2580 EINPFTGLVTVKDSLVGMENRIFNFKVQA--RDGSLPFY-NATVPVQVRVLPPEVPLPQF 2636
Query: 680 AHSPIIFHVKENS-AGAAIGQI-FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-G 736
+ F E++ G IG + +N IY GN + N +D ++ ED G
Sbjct: 2637 SEPLYTFSAVEDAPVGTEIGSVRAASNTPLIYSLVDGNT---LENNKDKV--FSLDEDSG 2691
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
T+ QKP+D E+ Y++ V+A+ N + A + ++I ++D NDN P+F+ + Y F+
Sbjct: 2692 TLVLQKPMDHERTKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLFDASPYRAFL 2751
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTL---------FGEGKEMFDVDENTGVVK 847
EN GT + + A DAD TN L Y+L EMF +DE +G +
Sbjct: 2752 AENMPAGTTVIQ---VTANDADSETNGLVTYSLEALPEEEEEEAGATEMFSIDEESGWIT 2808
Query: 848 FIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFN 894
++ D E +Y+ S+VA D GG LSS + + + DENDN P+F+
Sbjct: 2809 TTQEA-DCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFS 2857
Score = 144 bits (349), Expect = 2e-32
Identities = 237/1004 (23%), Positives = 394/1004 (39%), Gaps = 154/1004 (15%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++F V + L D NDN P F S Y+ S++S G+ + + A D D G+N V Y +
Sbjct: 2510 VAFCTVRIILTDENDNVPQFAASE-YQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTV 2568
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
T +INP TG V+V +S L G Q + S Y+ A V ++V
Sbjct: 2569 DEAEEAT-EDVIEINPFTGLVTVKDS--LVGMENRIFNFKVQARDGSLPFYN-ATVPVQV 2624
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
R P +P F Y F + +GT +G +R N + V + L ++
Sbjct: 2625 -RVLPPEVP-LPQFSEPLYTFSAVEDAPVGTEIGSVRAASNTPLIYSLVDGNTLENNKDK 2682
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDVNDERG 674
V F+++E SG + + + Y + +A Q N N ++ + + ++ V DVND
Sbjct: 2683 V-FSLDEDSGTLVLQKPMDHERTKWYQIDVMA-QGNHNGTAVASLVSISIQVQDVNDNEP 2740
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQD---VTDD 729
+ SP + EN AG + Q+ + S G T ++ L +++ T+
Sbjct: 2741 LF---DASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATEM 2797
Query: 730 IAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+I E+ G I T + D E VYR +V+A N G + + V + + DENDNPP F
Sbjct: 2798 FSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFS 2857
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT--GVV 846
Y G ++ENS G E+ + D + Y G+ F + + + G
Sbjct: 2858 LEAYRGSVVENSSPG-EVLVSMTTADADVSLENRLVTCYITDGDPLGHFAIIQQSEGGWG 2916
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ LDRE K + L ++A D G + + + + D NDN P+ Q+ ++
Sbjct: 2917 LILTQPLDREVKDRHALRVMATD-GKFQASVSVDVHVLDINDNSPQCEQL-------VYT 2968
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E ++E P ++F L V + P D G NGQ+
Sbjct: 2969 E---------AVMENSPSSRFVLKVSAVDP----------------------DVGANGQV 2997
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN 1024
Y + +AD F +N R G ++ L E+ E+ L A DGG
Sbjct: 2998 SYSLHGP--------NADK------FHLNYRTGELLTLAVLDREAEPEYNLVAKATDGGG 3043
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+ + + ++D+ND+ P F + Y V + + + A D
Sbjct: 3044 RSCQSDILLMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAKD------------- 3090
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
DT F + +G+L + L + + L V A D G +
Sbjct: 3091 --PDTCSFFSLDEFSGLLRLERPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSL 3148
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
+D P F + + + PE+ + + V+ + P+ + +
Sbjct: 3149 DDYQPVFLSSEYTAQL--PESFAVGS----QVLSLSALTRDGGGPDPVAYRIVSGNEDGR 3202
Query: 1205 DFIGNGNGLILYSLP---------QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKP 1255
+ + GL+ P + G +LS +MV V DV D + P
Sbjct: 3203 FLLDSRTGLLTLVAPLDFEASRTYYLSVEGRRGKQTLSDITTVMVNVTDVND-----NAP 3257
Query: 1256 VFISRYYELEIEEN-------VNAPVE-------LVSLNLTEHYENFKMRYYILNENDTD 1301
VF Y +EI+E+ + P + V+ + + N +RY I++ D
Sbjct: 3258 VFEEGGYRVEIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSLLRYSIVS---GD 3314
Query: 1302 IRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPV-AEDVLEGMT 1360
+ F I PR+G + + + DRE E+PH V A D +
Sbjct: 3315 PLQQFSIHPRSGEISVAAALDRE------------------EVPHYSLTVQAADGGDPPL 3356
Query: 1361 KYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ V + + DVNDN P F+ N L+ + P G V+QL
Sbjct: 3357 SSAILVTITVADVNDNPPIFSRVNHSLL--LQEGEPVGSSVLQL 3398
Score = 125 bits (302), Expect = 8e-27
Identities = 134/476 (28%), Positives = 211/476 (44%), Gaps = 36/476 (7%)
Query: 431 NIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
NI YD Q ++ V VT+ D NDN P F Y + NA+V +V+ A DP
Sbjct: 747 NITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLR-YVTRVPENAEVDSVVFTAHAADP 805
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPAN 544
DL G + + L LT T+ F I+P TG V++ ++P+ RH L + A D A
Sbjct: 806 DLDVGGRLRFSL-----LTPTNAFSIDPVTGEVTL-KAPLDRETTPRHDLQIVAKD-GAE 858
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR-VN-DAFE 602
R S VV + V + P P F+ Y+ V ++ +GT + + V+ D
Sbjct: 859 RGPRLVS--VVDLVVVLQDVNDNP--PRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLAS 914
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN- 661
V+Y+L + EG F ++ +G +T+ +L R Y A+ S+ ++
Sbjct: 915 GGLVTYNLKN--PEGGSFRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPRSLSSSC 972
Query: 662 -ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ V+DVN+ L + S ++ A + S G RF I
Sbjct: 973 FVEIEVLDVNEN---LHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRFHI 1029
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ + E G I + K LDREK Y ++V+ + G V + + D
Sbjct: 1030 QDGSGLGVFSIDEETGVICSAKILDREKMPHYWLSVLVG-DLGTEPLLSWTHVFLRVLDV 1088
Query: 781 NDNPPVFEHATYEGFIMEN-SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
NDN P Y + EN +G+ + + ATDAD + + + + FDV
Sbjct: 1089 NDNAPQLSQPVYFASVQENVDGVGSVAQ----VWATDADASSEGKLSFHMLESHRTHFDV 1144
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
D TGVV + +LDRE+K + + +V D G LSS ++I + D+NDN+P+F
Sbjct: 1145 DPKTGVVSTL-SALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPKF 1199
Score = 123 bits (297), Expect = 3e-26
Identities = 125/448 (27%), Positives = 204/448 (45%), Gaps = 30/448 (6%)
Query: 412 APLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKS 471
APL++ T D + E +L+S V++ V L D NDN P F+P N Y+ +
Sbjct: 837 APLDRETTPRHDLQIVAKDGAER-GPRLVSVVDLVVVLQDVNDNPPRFLPHN-YKIKVPE 894
Query: 472 NAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR 531
+ VGT++ V++VD DL G+V Y+L+ F+++ +TG +++ E R
Sbjct: 895 DLPVGTLLLWVESVDLDLASGGLVTYNLKNPEG----GSFRLDSSTGALTLERELDFERR 950
Query: 532 --HALFVEASDQPANPSERRYSLAVVTIEVTRGTKG-NKPDIPDFMGAPYEFWVGSNVGI 588
+ L V A D S S V IEV + ++P +F+ YE V + +
Sbjct: 951 RSYTLTVRAVDHGLPRS--LSSSCFVEIEVLDVNENLHRPLFSEFV---YEAAVMEDAAV 1005
Query: 589 GTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE 646
GTSV ++ + D + + + G GV F+++E +GVI L R P Y
Sbjct: 1006 GTSVLKLTASDKDVGRDGEFRFHIQDGSGLGV-FSIDEETGVICSAKILDREKMPHYWLS 1064
Query: 647 AVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIF-HVKENSAG-AAIGQIFHT 703
+ L T+ + V+DVND L P+ F V+EN G ++ Q++ T
Sbjct: 1065 VLVGDLGTEPLLSWTHVFLRVLDVNDNAPQL----SQPVYFASVQENVDGVGSVAQVWAT 1120
Query: 704 NMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKG 763
+ + + G + F + D+ + G + T LDRE+++ + + V+ N G
Sbjct: 1121 DADA---SSEGKLSFHMLESHRTHFDVD-PKTGVVSTLSALDREEKEEHSVEVVVSDN-G 1175
Query: 764 VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA 823
S + V I + D+NDN P F + I E + E ++ ++ A D D G+NA
Sbjct: 1176 SPSLSSTTTVVIRVLDDNDNQPKFTDKLFHIKIPEQRRSAGEQEVYRMV-ARDDDRGSNA 1234
Query: 824 LFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y L + E F +D GVV GD
Sbjct: 1235 AVTYRLQDDHSERFKIDPLLGVVTARGD 1262
Score = 111 bits (268), Expect = 1e-22
Identities = 127/510 (24%), Positives = 226/510 (44%), Gaps = 53/510 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
V V + D ND+ P F SNL + + +++ G V+ + AVD DLG+N +LY L+
Sbjct: 2000 VRVFIDDVNDSPPQF--SNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLEEDY 2057
Query: 504 NLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+L F+I+P+ G +S+ E ++ L V A D+ PS + A ++++V
Sbjct: 2058 SL-----FRIDPHAGDISLQRPLDFEALNKYVLTVLAVDE-GEPSHS--ATAQLSLQVRN 2109
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE---GV 618
+ P F Y V N+ T++ ++ +N Y L++ +E
Sbjct: 2110 QSS------PVFQTLLYPLKVPENIPPFTTILHVQA-----RNPDGYRLVYNLQEENASK 2158
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F ++ ++GV+TV D L ++ + A + + + V DVND V +
Sbjct: 2159 HFHIDFKTGVLTVTDPLDYESQRAHVLTVRASDSVTGVFSEASVEIEVEDVNDNAPVFSQ 2218
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGT 737
A+ ++ + G ++ Q+ ++ S G ++ +++ T+ I G
Sbjct: 2219 RAYGAVV--AEGLPVGTSVVQVSASDGDS--GRNRDLTFHMLRTERNETEFFDIDPHTGV 2274
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T++ LD E + + + + A N G + V + + D NDNPP F + YE +
Sbjct: 2275 IVTKQVLDHEGTNQFHLKIRATDN-GTAPLSSEASVLVNVTDVNDNPPDFVSSQYEATLD 2333
Query: 798 ENSKIGTEIKMDNIIKATDADEG-TNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E +K G + I+A+D D G N L L G F++++++G+V F + R
Sbjct: 2334 EKAKCGHIVIK---IQASDPDSGDLNKLQYKILSGNEGRYFNINQSSGIVSF-SNVCRRN 2389
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ------IEENSKV-------- 902
+ Y L++ D G A + I + N + P F Q + EN++V
Sbjct: 2390 LEPFYNLTVAVSD-GVFQKTARVNIDMLSTNKHSPSFKQSVYEAELAENAEVGTQVIRLA 2448
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVD 932
I + L G+ +TII K A+D D
Sbjct: 2449 AIDPDEGLYGSVDYTIINKLADEKLAIDSD 2478
Score = 110 bits (265), Expect = 2e-22
Identities = 161/691 (23%), Positives = 294/691 (42%), Gaps = 51/691 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y L + F++ G + LD + L + L+V
Sbjct: 445 VSATDADGGKNAFVTYALANSGPSP-FTIHPFTGVISTSGHLD----YELMRRRYHLRVW 499
Query: 278 ASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +P + ++ V I L ++NDN+P E N ++ + P G +V+Q+ A D D+
Sbjct: 500 ASDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPVDAPVGGTVVQLSAIDPDEL 559
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
+ + Q + F++D SG ++++ + S + V A + + A
Sbjct: 560 QQLRYLIQSGNELQVFAVDSVSGVISLKRAI---PPSEGSFTLSVAATDGRHQ---SEAA 613
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYY--DEQLMSFVNVEVTLLDAND 454
R+ R T A E T + +++E + E+ +F +V VT N
Sbjct: 614 VVRVTVTHRGEEATVACQE--TGISKQLTARLIQSMEPFLAQEEDEAFPDVHVT----NR 667
Query: 455 NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKIN 514
++P F P + + + + + +++A D D G +++Y + + F I+
Sbjct: 668 HSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGNQ---DGCFSID 724
Query: 515 PNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
G + + S E R+A +V ++ + V + VT + P P+F
Sbjct: 725 TFAGDLRLVCSLDRE-RNAFYVLNITVYDLGMPQKTAWRFVAVTVT--DVNDNP--PEFD 779
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV-PFAVEERSGVITVVD 633
Y V N + + V + A DV L F+++ +G +T+
Sbjct: 780 QLRYVTRVPENAEVDSVV--FTAHAADPDLDVGGRLRFSLLTPTNAFSIDPVTGEVTLKA 837
Query: 634 DLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
L R P +D + VA + L V + V + DVND L H+ I ++
Sbjct: 838 PLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFL--PHNYKIKVPED 895
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
G + + ++ G G V + + N + + + + G + ++ LD E+R
Sbjct: 896 LPVGTLLLWVESVDLDLASG---GLVTYNLKNPEGGSFRLD-SSTGALTLERELDFERRR 951
Query: 751 VYRMTVIAEFNKGV---ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
Y +TV A + G+ +S + ++ + +EN + P+F YE +ME++ +GT +
Sbjct: 952 SYTLTVRA-VDHGLPRSLSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTSVL 1010
Query: 808 MDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ A+D D G + F + + G G +F +DE TGV+ LDREK Y LS++
Sbjct: 1011 K---LTASDKDVGRDGEFRFHIQDGSGLGVFSIDEETGVI-CSAKILDREKMPHYWLSVL 1066
Query: 867 ARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
D G L S + + + D NDN P+ +Q
Sbjct: 1067 VGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQ 1097
Score = 109 bits (262), Expect = 6e-22
Identities = 120/443 (27%), Positives = 191/443 (43%), Gaps = 40/443 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ S +VE+ + D NDN PVF Y + VGT + +V A D D G+N + +
Sbjct: 2196 VFSEASVEIEVEDVNDNAPVF-SQRAYGAVVAEGLPVGTSVVQVSASDGDSGRNRDLTFH 2254
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVT 556
+ RT T F I+P+TG + + EG + L + A+D P S+ V
Sbjct: 2255 MLRTER-NETEFFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATDNGTAPLSSEASVLVNV 2313
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGY 614
+V + P PDF+ + YE + G V +I+ + D+ + N + Y +L G
Sbjct: 2314 TDV-----NDNP--PDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNKLQYKILSG- 2365
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
EG F + + SG+++ + R P Y NL++ + V
Sbjct: 2366 NEGRYFNINQSSGIVSFSNVCRRNLEPFY-----------NLTVAVSDGVFQKTARVNID 2414
Query: 675 VLLKGAHSPII---FHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+L HSP + E + A +G Q+ G+V + I N+ + +
Sbjct: 2415 MLSTNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKL-ADEKL 2473
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
AI DG + T +PLDRE R+ + K V I + DENDN P F +
Sbjct: 2474 AIDSDGQMVTTQPLDRE-NPAQRIIAVKVMAKDGGGKVAFCTVRIILTDENDNVPQFAAS 2532
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVV 846
Y+ I G+ + I A DADEG NA YT+ E +E + +++ TG+V
Sbjct: 2533 EYQVSIQSTVNKGSPVVH---IMAYDADEGRNADVTYTV-DEAEEATEDVIEINPFTGLV 2588
Query: 847 KFIGDSLDREKKIMYKLSLVARD 869
+ DSL + ++ + ARD
Sbjct: 2589 T-VKDSLVGMENRIFNFKVQARD 2610
Score = 105 bits (251), Expect = 1e-20
Identities = 118/481 (24%), Positives = 210/481 (43%), Gaps = 54/481 (11%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + + V+V+V +LD NDN+P +Y ++ N+ + KV AVDPD+G NG V
Sbjct: 2939 DGKFQASVSVDVHVLDINDNSPQ-CEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQV 2997
Query: 496 LYDLQRTSNLTITSPFKINPNTG---TVSVAESPILEGRHALFVEASDQPANPSERRYSL 552
Y L + F +N TG T++V + E + L +A+D + L
Sbjct: 2998 SYSLHGPN----ADKFHLNYRTGELLTLAVLDRE-AEPEYNLVAKATDGGGRSCQSDILL 3052
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
+ + + P P F + Y+ V N + T + + D + S+
Sbjct: 3053 MIQDM-------NDNP--PRFSSSHYQLTVFDNTTVHTPIAVLYAKD---PDTCSF---- 3096
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDVN 670
F+++E SG++ + L+ P ++ + A +L + TV VV ++
Sbjct: 3097 -------FSLDEFSGLLRLERPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLD 3149
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + V L ++ + E+ A + Q+ + + G G V + I + + +
Sbjct: 3150 DYQPVFLSSEYTA---QLPESFAVGS--QVLSLSALTRDGGGPDPVAYRIVSGNEDGRFL 3204
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G + PLD E Y ++V E +G + + I V + + D NDN PVFE
Sbjct: 3205 LDSRTGLLTLVAPLDFEASRTYYLSV--EGRRGKQTLSDITTVMVNVTDVNDNAPVFEEG 3262
Query: 791 TYEGFIMENSKIGTEIK---------MDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD 840
Y I E+ G+ + + A+D D +N+L Y++ G+ + F +
Sbjct: 3263 GYRVEIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIH 3322
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEE 898
+G + + +LDRE+ Y L++ A D G LSS + I + D NDN P F+++
Sbjct: 3323 PRSGEIS-VAAALDREEVPHYSLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNH 3381
Query: 899 N 899
+
Sbjct: 3382 S 3382
Score = 96.7 bits (230), Expect = 4e-18
Identities = 116/428 (27%), Positives = 174/428 (40%), Gaps = 39/428 (9%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T + LD E + Y+ V A G +V I ++DENDN P F +YE
Sbjct: 378 GVIVTTQKLDYESKRRYQFDVAAN------GGEAEARVVIEVKDENDNSPQFASPSYEAS 431
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ EN+ +G+ + + ATDAD G NA Y L G F + TGV+ G LD
Sbjct: 432 LDENAPVGSSVLQ---VSATDADGGKNAFVTYALANSGPSPFTIHPFTGVISTSG-HLDY 487
Query: 856 E-KKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
E + Y L + A D+G SE + I + + NDN P ++ N+ + + +
Sbjct: 488 ELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPV------D 541
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
G T++++ A+D D+L L + I G +++ A+D SG+ R
Sbjct: 542 APVGGTVVQLS-----AIDPDELQQLRYL---IQSGNE-LQVFAVDSVSGVISLKRAIPP 592
Query: 972 SEVYIPPSKLSADALEVKRYFV----INERHGHVIVA---RSLPPESEFRLNISALDGGN 1024
SE S + D V + R VA + + RL I +++
Sbjct: 593 SEGSFTLSVAATDGRHQSEAAVVRVTVTHRGEEATVACQETGISKQLTARL-IQSMEPFL 651
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTW-YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+ V N H P F + + E + ++ ATDAD G + L Y
Sbjct: 652 AQEEDEAFPDVHVTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYA 711
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
I + D F I G L + LDRE Y+L + D G D
Sbjct: 712 ISAGNQDGCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLG-MPQKTAWRFVAVTVTD 770
Query: 1144 VNDNSPKF 1151
VNDN P+F
Sbjct: 771 VNDNPPEF 778
Score = 95.1 bits (226), Expect = 1e-17
Identities = 187/795 (23%), Positives = 311/795 (39%), Gaps = 94/795 (11%)
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+G PF + +GVI L ++ Y F+ A A +V + V D ND
Sbjct: 367 DGAPFRINPLTGVIVTTQKLDYESKRRYQFDVAANGGEAEARVV----IEVKDENDNSPQ 422
Query: 676 LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
++ + EN+ G+++ Q+ T+ G V + +AN I
Sbjct: 423 FASPSYEA---SLDENAPVGSSVLQVSATDAD---GGKNAFVTYALANSGPSPFTIH-PF 475
Query: 735 DGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I T LD E R Y + V A + S VTI + + NDN P+ E
Sbjct: 476 TGVISTSGHLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCN 535
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
+ ++ +G + + A D DE ++ G ++F VD +GV+
Sbjct: 536 TTLPVDAPVGGTVVQ---LSAIDPDELQQLRYLIQ-SGNELQVFAVDSVSGVISLKRAIP 591
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMI----GDENDNKPEFNQIEENSKVRI--HRE 907
E + LS+ A D G SEA ++ + G+E + I + R+ E
Sbjct: 592 PSEGS--FTLSVAATD-GRHQSEAAVVRVTVTHRGEEATVACQETGISKQLTARLIQSME 648
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQI 966
L +V N+ + D + P + + E+ P+ +++++L A D DSG +
Sbjct: 649 PFLAQEEDEAFPDVHVTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLL 708
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN 1024
Y ++ + D F I+ G + + SL E + LNI+ D G
Sbjct: 709 VYAISAG--------NQDGC-----FSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGM 755
Query: 1025 LNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
V V V DVND+ P F + Y V E V+ A D D L +
Sbjct: 756 PQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRF 815
Query: 1083 -FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX-XXXXXXXXXXX 1140
+ P++ F I P+TG +++ LDRET ++ L +VA+D
Sbjct: 816 SLLTPTNA---FSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVV 872
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNF--ESVMM------IPVYKATIEENAPI 1192
DVNDN P+F + + K PE + ESV + + Y E
Sbjct: 873 LQDVNDNPPRFLPHNYKI--KVPEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEGGSF 930
Query: 1193 ---GTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLP-SLSSTAILMVTVADVPDE 1248
+T A + DF + Y+L R GLP SLSS+ + + V DV +
Sbjct: 931 RLDSSTGALTLERELDFERRRS----YTLTVRAVDH--GLPRSLSSSCFVEIEVLDVNEN 984
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTF 1306
+ +P+F YE + E+ ++ L ++ + + R++I + + + F
Sbjct: 985 LH---RPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGV---F 1038
Query: 1307 VIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKV 1366
ID G + + DRE Y + V ++ + + L T V
Sbjct: 1039 SIDEETGVICSAKILDREKMPHYWLSV-------------LVGDLGTEPLLSWT----HV 1081
Query: 1367 VVRIKDVNDNSPKFT 1381
+R+ DVNDN+P+ +
Sbjct: 1082 FLRVLDVNDNAPQLS 1096
Score = 91.5 bits (217), Expect = 2e-16
Identities = 92/314 (29%), Positives = 136/314 (43%), Gaps = 25/314 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSL 128
G+ Q +A+ V V + DVNDN P F Y V E F A +G L
Sbjct: 754 GMPQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRL 813
Query: 129 TIPLTVPRGLTIFKDIRA-----FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
L P + D+ TP D+ G + G L S V++
Sbjct: 814 RFSLLTPTNAFSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGP-RLVSVVDLVVV 872
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
L+ V D I +L + ++D DL G + Y L +
Sbjct: 873 LQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLW--VESVDLDLASGGLVTYNL-KNPEGGS 929
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK-TAQARVEIELLDLNDN 302
F LDS G+L LE+ELD + + ++ L V+A P ++ VEIE+LD+N+N
Sbjct: 930 FRLDSSTGALTLERELDFE-----RRRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNEN 984
Query: 303 L--PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK--GAFSIDPRS 358
L P F Y +++E+ G SVL++ A+DKD G +GEF + + D G FSID +
Sbjct: 985 LHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGVFSIDEET 1044
Query: 359 GWLTVRNQTVLDRE 372
G + + +LDRE
Sbjct: 1045 G--VICSAKILDRE 1056
Score = 91.5 bits (217), Expect = 2e-16
Identities = 123/467 (26%), Positives = 196/467 (41%), Gaps = 45/467 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI-GK------VKAVDPDLGQNG 493
+FV++ VT D NDN PVF Y + A +G ++ G+ ++A D D N
Sbjct: 1686 TFVSIYVT--DENDNAPVFRQKE-YLGQISEAADIGAMVTGEGSRPLVIQASDADRDANA 1742
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYS 551
+++Y + L++ F I+P+ GT+S+ + E R + V+ D P
Sbjct: 1743 LLVYQILEPELLSV---FSIDPSMGTISLLSAVDFEARAEYRFSVQVRDS-GEPCRYAAE 1798
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
A VT+ V P F YE V G V + DA + V+Y ++
Sbjct: 1799 PAKVTVRVL----DLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDA--DSAVAYSIV 1852
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G G F+VE SG+ITV + F + L+ + L ATV V
Sbjct: 1853 EGNLHGA-FSVEPSSGLITVSNATG-----FTGFYQLVLRASDGLH-QDLATVRV----- 1900
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
G L G H V S + + ++++ G L+ + + +
Sbjct: 1901 -NGSALTGGHLGFEQDVYTVSVAENLRTV--RTLAALKARGCLFNEPLVFSLLNPEGKFS 1957
Query: 732 I-AEDGTIFTQK-PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I A G + T P DRE+ DVY + V+ + A QV ++I+D ND+PP F +
Sbjct: 1958 ISASSGVLETTGIPFDREETDVYEVVVMVRDTRTPPRTARA-QVRVFIDDVNDSPPQFSN 2016
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
+ I E+S+ G + A D D G NA +Y+L E +F +D + G + +
Sbjct: 2017 LPFSIVIPESSEPGDVLYQ---ASAVDGDLGENASILYSL-EEDYSLFRIDPHAGDIS-L 2071
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
LD E Y L+++A D G S A + + N + P F +
Sbjct: 2072 QRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQVRNQSSPVFQTL 2118
Score = 83.0 bits (196), Expect = 6e-14
Identities = 88/329 (26%), Positives = 150/329 (45%), Gaps = 27/329 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF--IFLIAPIGPSLTIPLTVP 135
+A V V+I+DVND+ P F + P+ + + E + G+ + + +G + +I ++
Sbjct: 1995 TARAQVRVFIDDVNDSPPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLE 2054
Query: 136 RGLTIFK-DIRAFD--RDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYD 191
++F+ D A D +P + Y + V D+G E SH L + +
Sbjct: 2055 EDYSLFRIDPHAGDISLQRPLDFEALNKYVLTVLAVDEG----EPSHSATAQLSLQVR-N 2109
Query: 192 AGDKEFQLVIMASGKRIHKEIL-FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
FQ ++ ++ + I F +H ++ G L Y L N K F +D
Sbjct: 2110 QSSPVFQTLLYPL--KVPENIPPFTTILHVQARNPD-GYRLVYNLQEENASKHFHIDFKT 2166
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G L + LD +++ VL V+AS + ++A VEIE+ D+NDN P F
Sbjct: 2167 GVLTVTDPLDYESQR-----AHVLTVRASDSVTGV-FSEASVEIEVEDVNDNAPVFSQRA 2220
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQ 366
Y + E LP G SV+QV A+D D G N + T+ + + F IDP +G + +
Sbjct: 2221 YGAVVAEGLPVGTSVVQVSASDGDSGRNRDLTFHMLRTERNETEFFDIDPHTGVIVTKQ- 2279
Query: 367 TVLDREAHSSLRMKVYAKETNPSVVGTFA 395
VLD E + +K+ A + + + + A
Sbjct: 2280 -VLDHEGTNQFHLKIRATDNGTAPLSSEA 2307
Score = 80.6 bits (190), Expect = 3e-13
Identities = 105/442 (23%), Positives = 180/442 (40%), Gaps = 47/442 (10%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + + D NDN P F S+ Y+ ++ N V T I + A DPD + L S
Sbjct: 3049 DILLMIQDMNDNPPRFSSSH-YQLTVFDNTTVHTPIAVLYAKDPDTCS----FFSLDEFS 3103
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
L + + P+ P E L V+A+D+ YS+A VT+ V
Sbjct: 3104 GL-LRLERPLTPDA-------PPTFE----LKVKATDRGL--PRHLYSIATVTVAVVSLD 3149
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFA 621
P F+ + Y + + +G+ V + D + V+Y ++ G E+G F
Sbjct: 3150 DYQ----PVFLSSEYTAQLPESFAVGSQVLSLSALTRDGGGPDPVAYRIVSGNEDG-RFL 3204
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
++ R+G++T+V L Y + LS +T V+V DVND V +G +
Sbjct: 3205 LDSRTGLLTLVAPLDFEASRTYYLSVEGRRGKQTLSDITTVMVNVTDVNDNAPVFEEGGY 3264
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYG--------NGTGN--VRFLIANQQDVTDDIA 731
+KE+ ++ ++G +G N +R+ I + +
Sbjct: 3265 R---VEIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSI 3321
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
G I LDRE+ Y +TV A+ +S A + VTI + D NDNPP+F
Sbjct: 3322 HPRSGEISVAAALDREEVPHYSLTVQAADGGDPPLSSAIL--VTITVADVNDNPPIFSRV 3379
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
+ + E +G+ + + ++ D + + G + F VD+ G++
Sbjct: 3380 NHSLLLQEGEPVGSSV-LQLVVTDRDTPRNGPPFSFHIVSGNQERRFHVDQG-GLLSL-- 3435
Query: 851 DSLDREKKIMYKLSLVARDTGG 872
S KK+ L + TGG
Sbjct: 3436 -SAPLRKKVKGHHQLKIQVTGG 3456
Score = 77.0 bits (181), Expect = 4e-12
Identities = 54/161 (33%), Positives = 79/161 (49%), Gaps = 18/161 (11%)
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ-ARVEI 294
+ N K+FSLD +G+L L+K +D + + + + V A +N A + I
Sbjct: 2676 LENNKDKVFSLDEDSGTLVLQKPMDHE-----RTKWYQIDVMAQGNHNGTAVASLVSISI 2730
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-------DD 347
++ D+NDN P F+ Y + EN+P G +V+QV A D D NG TY L ++
Sbjct: 2731 QVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEE 2790
Query: 348 PKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
GA FSID SGW+T + D EA R V A +
Sbjct: 2791 EAGATEMFSIDEESGWITTTQEA--DCEAVRVYRFSVVATD 2829
Score = 76.6 bits (180), Expect = 5e-12
Identities = 124/507 (24%), Positives = 199/507 (39%), Gaps = 108/507 (21%)
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
F + V N + DQL + +PEN + + + +A D D + G++R+ +
Sbjct: 763 FVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRF----SLL 818
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGG----NLNDNI 1029
P + S D + G V + L E+ R L I A DG L +
Sbjct: 819 TPTNAFSIDPVT-----------GEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVV 867
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+ V ++DVND+ P F Y V E +L V++ D D +TY ++ +
Sbjct: 868 DLVVVLQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEG 927
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN-- 1147
F + TG L++ ELD E Y LTV A D+G DVN+N
Sbjct: 928 G-SFRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNENLH 986
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD-- 1205
P F F VY+A + E+A +GT+V K+ A+D D
Sbjct: 987 RPLFSEF--------------------------VYEAAVMEDAAVGTSVLKLTASDKDVG 1020
Query: 1206 -------FIGNGNGLILYSLPQ------------RKNQQ---------NLGLPSLSSTAI 1237
I +G+GL ++S+ + R+ +LG L S
Sbjct: 1021 RDGEFRFHIQDGSGLGVFSIDEETGVICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTH 1080
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYIL 1295
+ + V DV D +PV+ + ++ENV+ + + T + K+ +++L
Sbjct: 1081 VFLRVLDVNDNAPQLSQPVYFA-----SVQENVDGVGSVAQVWATDADASSEGKLSFHML 1135
Query: 1296 NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDV 1355
+ R F +DP+ G + + + DRE K+ + V V V D
Sbjct: 1136 ESH----RTHFDVDPKTGVVSTLSALDREEKEEHSVEV-----------------VVSDN 1174
Query: 1356 LEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
VV+R+ D NDN PKFT+
Sbjct: 1175 GSPSLSSTTTVVIRVLDDNDNQPKFTD 1201
Score = 76.6 bits (180), Expect = 5e-12
Identities = 68/229 (29%), Positives = 103/229 (44%), Gaps = 21/229 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT+++KL A D D G +G+ R+ L V F I+E G
Sbjct: 999 VMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQD----------GSGLGV---FSIDEETG 1045
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNIS--VRVFVK--DVNDHFPVFKKTWYNFNVE 1055
+ A+ L E +S L G + + VF++ DVND+ P + Y +V+
Sbjct: 1046 VICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQ 1105
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V ATDAD L++ + S F++ P TGV+S LDRE +++
Sbjct: 1106 ENVDGVGSVAQVWATDADASSEGKLSFHMLESHRT-HFDVDPKTGVVSTLSALDREEKEE 1164
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
+ + VV DNG D NDN PKF D+L K PE
Sbjct: 1165 HSVEVVVSDNGSPSLSSTTTVVIRVLDD-NDNQPKF--TDKLFHIKIPE 1210
Score = 76.6 bits (180), Expect = 5e-12
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 15/210 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
IEV+ N A Q ++ E +P+GT++++++A D DSG N + +
Sbjct: 2204 IEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQVSASDGDSGRNRDLTFHM-------- 2255
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVF 1034
L + E + +F I+ G ++ + L E ++F L I A D G L+ SV V
Sbjct: 2256 --LRTERNETE-FFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATDNGTAPLSSEASVLVN 2312
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V DVND+ P F + Y ++E ++ K+ A+D D G L Y I + F
Sbjct: 2313 VTDVNDNPPDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNKLQYKILSGNEGRYFN 2372
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARD 1124
I+ +G++S + R E Y LTV D
Sbjct: 2373 INQSSGIVSFSNVCRRNLEPFYNLTVAVSD 2402
Score = 76.6 bits (180), Expect = 5e-12
Identities = 107/465 (23%), Positives = 191/465 (41%), Gaps = 33/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V V + D NDN P FV S YE ++ AK G ++ K++A DPD G + Y
Sbjct: 2303 LSSEASVLVNVTDVNDNPPDFVSSQ-YEATLDEKAKCGHIVIKIQASDPDSGDLNKLQYK 2361
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVT 556
+ + F IN ++G VS + LE + L V SD + R V
Sbjct: 2362 ILSGNE---GRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGVFQKTAR------VN 2412
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
I++ K + P F + YE + N +GT V ++ D E V Y +++
Sbjct: 2413 IDMLSTNKHS----PSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKL 2468
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+ A++ G + L R N P AV + V TV ++ + DE
Sbjct: 2469 AD-EKLAIDS-DGQMVTTQPLDREN-PAQRIIAVKVMAKDGGGKVAFCTVRII-LTDEND 2524
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ + A S + V S + H +V + + ++ T+D+
Sbjct: 2525 NVPQFAASE--YQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTVDEAEEATEDVIEIN 2582
Query: 735 --DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + + L + ++ V A A + V + + P F Y
Sbjct: 2583 PFTGLVTVKDSLVGMENRIFNFKVQARDGSLPFYNATV-PVQVRVLPPEVPLPQFSEPLY 2641
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+E++ +GTEI ++ A++ + + TL ++F +DE++G + +
Sbjct: 2642 TFSAVEDAPVGTEI--GSVRAASNTPLIYSLVDGNTLENNKDKVFSLDEDSGTL-VLQKP 2698
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELI---IMIGDENDNKPEFN 894
+D E+ Y++ ++A+ ++ A L+ I + D NDN+P F+
Sbjct: 2699 MDHERTKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLFD 2743
Score = 75.4 bits (177), Expect = 1e-11
Identities = 90/360 (25%), Positives = 148/360 (41%), Gaps = 42/360 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
VRVF+ DVND P F ++ + E+ VL + A D D G+NA++ Y ++ D
Sbjct: 2000 VRVFIDDVNDSPPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLE-EDYS 2058
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
L F I P G +S+ LD E +KY+LTV+A D G N +SP
Sbjct: 2059 L-FRIDPHAGDISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQVR---NQSSPV 2114
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
F L K PE N I +A + + + + A+ I
Sbjct: 2115 FQTL--LYPLKVPE-------NIPPFTTILHVQARNPDGYRLVYNLQEENASKHFHIDFK 2165
Query: 1211 NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD----KPVFISRYYELEI 1266
G++ + P Q + ++ ++ + ++ E+E+ D PVF R Y +
Sbjct: 2166 TGVLTVTDPLDYESQRAHVLTVRASDSVTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVV 2225
Query: 1267 EEN--VNAPVELVSLNLTEHYENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPD 1322
E V V VS + + N + +++L N+T+ F IDP G + + D
Sbjct: 2226 AEGLPVGTSVVQVSASDGDSGRNRDLTFHMLRTERNETEF---FDIDPHTGVIVTKQVLD 2282
Query: 1323 REVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
E + + + +RA + P++ + V+V + DVNDN P F +
Sbjct: 2283 HEGTNQFHLKIRATDNGTA--------PLSS---------EASVLVNVTDVNDNPPDFVS 2325
Score = 75.4 bits (177), Expect = 1e-11
Identities = 75/309 (24%), Positives = 135/309 (43%), Gaps = 25/309 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S+ SV V + DVNDN P F+ + Y T+DE G + I P
Sbjct: 2299 GTAPLSSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGH--IVIKIQASDPDSGDLN 2356
Query: 133 TVPRGLTIFKDIRAFDRDKPN---------TPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+ + + R F+ ++ + N + Y++ DG F +++ + +
Sbjct: 2357 KLQYKILSGNEGRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGVFQ-KTARVNIDM 2415
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
L + + +A + +++ + AID D G+ ++ Y +I+ +
Sbjct: 2416 LSTNKHSPSFKQSVYEAELAENAEVGTQVI---RLAAIDPDEGLYGSVDYTIINKLADEK 2472
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
++DS +G + + LD + N ++V A K A V I L D NDN+
Sbjct: 2473 LAIDS-DGQMVTTQPLDRE---NPAQRIIAVKVMAKDGGG--KVAFCTVRIILTDENDNV 2526
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPRSG 359
P+F Y +SI + G V+ +MA D D+G N + TY +D+ + A I+P +G
Sbjct: 2527 PQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTVDEAEEATEDVIEINPFTG 2586
Query: 360 WLTVRNQTV 368
+TV++ V
Sbjct: 2587 LVTVKDSLV 2595
Score = 75.4 bits (177), Expect = 1e-11
Identities = 160/696 (22%), Positives = 282/696 (40%), Gaps = 92/696 (13%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVL 496
+L S V VEVT+ D NDN P F Y S+ N+ G V+ + D D+ +N +V
Sbjct: 2835 RLSSSVLVEVTVTDENDNPPKF-SLEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVT 2893
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
+ L + + + G + P+ ++ RHAL V A+D S S+
Sbjct: 2894 CYITDGDPLGHFAIIQQSEG-GWGLILTQPLDREVKDRHALRVMATDGKFQAS---VSVD 2949
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
V +++ N P + Y V N V ++ D VSY L
Sbjct: 2950 VHVLDIN----DNSPQCEQLV---YTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSL- 3001
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
HG F + R+G + + L R P Y+ A A + S ++ + + D+ND
Sbjct: 3002 HG-PNADKFHLNYRTGELLTLAVLDREAEPEYNLVAKAT-DGGGRSCQSDILLMIQDMND 3059
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ +F +N+ HT ++ +Y F ++
Sbjct: 3060 NPPRFSSSHYQLTVF---DNTT-------VHTPIAVLYAKDPDTCSFFSLDEFS------ 3103
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA-GIYQVTIYIEDENDNPPVFEHA 790
G + ++PL + + + V A ++G+ I VT+ + +D PVF +
Sbjct: 3104 ----GLLRLERPLTPDAPPTFELKVKAT-DRGLPRHLYSIATVTVAVVSLDDYQPVFLSS 3158
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y + E+ +G+++ ++ T G + + + G F +D TG++ +
Sbjct: 3159 EYTAQLPESFAVGSQVL--SLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTGLLTLVA 3216
Query: 851 DSLDREKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LD E Y LS+ R LS +++ + D NDN P F E R+ E K
Sbjct: 3217 P-LDFEASRTYYLSVEGRRGKQTLSDITTVMVNVTDVNDNAPVF----EEGGYRV--EIK 3269
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
+ G +++V + P+F G K+ A D D N +RY
Sbjct: 3270 EDLPPGSLVMKVPAQEP---------PVF--------GG---KVTASDQDGPSNSLLRY- 3308
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--L 1025
S +S D L+ F I+ R G + VA +L E + L + A DGG+ L
Sbjct: 3309 ---------SIVSGDPLQ---QFSIHPRSGEISVAAALDREEVPHYSLTVQAADGGDPPL 3356
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA-NLTYFI 1084
+ I V + V DVND+ P+F + ++ ++E + + ++ TD D +N ++ I
Sbjct: 3357 SSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSSVLQLVVTDRDTPRNGPPFSFHI 3416
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
+ + F + G+LS++ L ++ + + L +
Sbjct: 3417 VSGNQERRFHVDQ-GGLLSLSAPLRKKVKGHHQLKI 3451
Score = 72.9 bits (171), Expect = 6e-11
Identities = 65/218 (29%), Positives = 100/218 (45%), Gaps = 24/218 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PENIP TTI+ + A + D ++ Y E ++F I+ + G
Sbjct: 2124 VPENIPPFTTILHVQARNPDGY---RLVYNLQEE-------------NASKHFHIDFKTG 2167
Query: 1000 HVIVARSLPPESEFR--LNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ V L ES+ L + A D + SV + V+DVND+ PVF + Y V E
Sbjct: 2168 VLTVTDPLDYESQRAHVLTVRASDSVTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAE 2227
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ +V A+D D G+N +LT+ + + ++T+ F+I P TGV+ LD E
Sbjct: 2228 GLPVGTSVVQVSASDGDSGRNRDLTFHMLRTERNETEF-FDIDPHTGVIVTKQVLDHEGT 2286
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+++ L + A DNG DVNDN P F
Sbjct: 2287 NQFHLKIRATDNG-TAPLSSEASVLVNVTDVNDNPPDF 2323
Score = 71.7 bits (168), Expect = 1e-10
Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 11/154 (7%)
Query: 759 EFNKGVISGAGIYQ-VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN----IIK 813
E + + GA V+IY+ DENDN PVF Y G I E + IG + + +I+
Sbjct: 1673 EVSASTVGGASSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLVIQ 1732
Query: 814 ATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
A+DAD NAL +Y + E +F +D + G + + ++D E + Y+ S+ RD+G
Sbjct: 1733 ASDADRDANALLVYQILEPELLSVFSIDPSMGTISLL-SAVDFEARAEYRFSVQVRDSGE 1791
Query: 873 ----LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ A++ + + D ND P F S V
Sbjct: 1792 PCRYAAEPAKVTVRVLDLNDCAPHFTSPVYESSV 1825
Score = 71.3 bits (167), Expect = 2e-10
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 9/176 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D+G R+ + G+ +FS+D G + K LD + + + L V
Sbjct: 1014 ASDKDVGRDGEFRFHIQDGSGLGVFSIDEETGVICSAKILDREKMPH-----YWLSVLVG 1068
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
L + V + +LD+NDN P+ Y S+ EN+ SV QV ATD D G
Sbjct: 1069 DLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEG 1128
Query: 340 EFTY-QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
+ ++ L+ + F +DP++G V + LDRE ++V + +PS+ T
Sbjct: 1129 KLSFHMLESHRTHFDVDPKTG--VVSTLSALDREEKEEHSVEVVVSDNGSPSLSST 1182
Score = 71.3 bits (167), Expect = 2e-10
Identities = 51/187 (27%), Positives = 88/187 (47%), Gaps = 12/187 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +GT +I+L A+D D GL G + Y +++ + +D V + E
Sbjct: 2434 LAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKLADEKLAIDSDGQMVTTQPLDRENPA 2493
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
I+A + + A DGG +VR+ + D ND+ P F + Y +++
Sbjct: 2494 QRIIA----------VKVMAKDGGGKVAFCTVRIILTDENDNVPQFAASEYQVSIQSTVN 2543
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSD--TDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + A DAD G+NA++TY + ++ T+ EI+P TG+++V L +
Sbjct: 2544 KGSPVVHIMAYDADEGRNADVTYTVDEAEEATEDVIEINPFTGLVTVKDSLVGMENRIFN 2603
Query: 1118 LTVVARD 1124
V ARD
Sbjct: 2604 FKVQARD 2610
Score = 70.1 bits (164), Expect = 4e-10
Identities = 89/323 (27%), Positives = 137/323 (42%), Gaps = 40/323 (12%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTV-DELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
S + + I+D+NDN P F + Y +TV D T A ++ P S
Sbjct: 3045 SCQSDILLMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAKDPDTCSFF------- 3097
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDG-HFALESSHKPVLLLRKVLDYDAGD 194
L F + +R P TP++ + + V D G L S + + + DY
Sbjct: 3098 SLDEFSGLLRLER--PLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVF 3155
Query: 195 KEFQLVI-MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
+ + + ++L + A+ +D G + Y ++SGN+ F LDS G L
Sbjct: 3156 LSSEYTAQLPESFAVGSQVL---SLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTGLL 3212
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
L LD +A + T+ L V+ + L V + + D+NDN P FE Y +
Sbjct: 3213 TLVAPLDFEA-----SRTYYLSVEGRRGKQTLSDITT-VMVNVTDVNDNAPVFEEGGYRV 3266
Query: 314 SIVENLPNGFSVL------------QVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
I E+LP G V+ +V A+D+D N Y + DP FSI PRSG
Sbjct: 3267 EIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSG 3326
Query: 360 WLTVRNQTVLDRE--AHSSLRMK 380
++V LDRE H SL ++
Sbjct: 3327 EISV--AAALDREEVPHYSLTVQ 3347
Score = 68.9 bits (161), Expect = 1e-09
Identities = 86/333 (25%), Positives = 138/333 (41%), Gaps = 29/333 (8%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
VR + + + SV + +EDVNDN P+F Y V E P G + + A G S
Sbjct: 2187 VRASDSVTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSV-VQVSASDGDS 2245
Query: 128 -----LTIP-LTVPRGLTIFKDIRAFD-----RDKPNTPNSDVHYSIVSGNDDGHFALES 176
LT L R T F DI + + ++ + + D+G L S
Sbjct: 2246 GRNRDLTFHMLRTERNETEFFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATDNGTAPLSS 2305
Query: 177 SHKPVLLLRKVLDY--DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE 234
++ + V D D +++ + K H I I A D D G L+Y+
Sbjct: 2306 EASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGHIVI----KIQASDPDSGDLNKLQYK 2361
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
++SGN+ + F+++ +G + NL+ + L V S + + ARV I
Sbjct: 2362 ILSGNEGRYFNINQSSGIVSFSNV----CRRNLEP-FYNLTVAVS---DGVFQKTARVNI 2413
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
++L N + P F+ Y + EN G V+++ A D D+G G Y + + +
Sbjct: 2414 DMLSTNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKLADEKL 2473
Query: 355 DPRSGWLTVRNQTVLDRE--AHSSLRMKVYAKE 385
S V Q LDRE A + +KV AK+
Sbjct: 2474 AIDSDGQMVTTQP-LDRENPAQRIIAVKVMAKD 2505
Score = 68.5 bits (160), Expect = 1e-09
Identities = 58/195 (29%), Positives = 95/195 (48%), Gaps = 17/195 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D DLG A++ Y L D LF +D G + L++ LD +A N +VL V A
Sbjct: 2038 AVDGDLGENASILYSL--EEDYSLFRIDPHAGDISLQRPLDFEA-----LNKYVLTVLAV 2090
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P +A A++ +++ N + P F+ Y + + EN+P ++L V A + D G
Sbjct: 2091 DEGEPSHSATAQLSLQVR--NQSSPVFQTLLYPLKVPENIPPFTTILHVQARNPD-GYRL 2147
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQR 399
+ Q ++ F ID ++G LTV + LD E S R V + SV G F+++
Sbjct: 2148 VYNLQEENASKHFHIDFKTGVLTVTDP--LDYE---SQRAHVLTVRASDSVTGVFSEAS- 2201
Query: 400 IAKWRRQPLETNAPL 414
+ + + NAP+
Sbjct: 2202 -VEIEVEDVNDNAPV 2215
Score = 68.1 bits (159), Expect = 2e-09
Identities = 67/190 (35%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + + D NDN+P F S YE S+ NA VG+ + +V A D D G+N V Y L +
Sbjct: 409 VVIEVKDENDNSPQFA-SPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANSG- 466
Query: 505 LTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
SPF I+P TG +S + + ++ R+ L V ASD + S R S VTI +
Sbjct: 467 ---PSPFTIHPFTGVISTSGHLDYELMRRRYHLRVWASDSGSPFS--RVSECPVTITL-N 520
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N P + + +G V + VG GT V Q+ D E + Y + G E V FA
Sbjct: 521 NVNDNIP-LLERVGCNTTLPVDAPVG-GTVV-QLSAIDPDELQQLRYLIQSGNELQV-FA 576
Query: 622 VEERSGVITV 631
V+ SGVI++
Sbjct: 577 VDSVSGVISL 586
Score = 66.9 bits (156), Expect = 4e-09
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D A L Y+++ +FS+D G++ L +D +A + F +
Sbjct: 1728 PLVIQASDADRDANALLVYQILEPELLSVFSIDPSMGTISLLSAVDFEARAEYR---FSV 1784
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
QV+ S A+V + +LDLND P F Y S++ G V V A D D
Sbjct: 1785 QVRDSGEPCRYAAEPAKVTVRVLDLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDAD 1844
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQT 367
++ + GAFS++P SG +TV N T
Sbjct: 1845 SAV--AYSIVEGNLHGAFSVEPSSGLITVSNAT 1875
Score = 64.9 bits (151), Expect = 2e-08
Identities = 48/172 (27%), Positives = 88/172 (51%), Gaps = 9/172 (5%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+F + A DQD + LRY ++SG+ + FS+ +G + + LD + + +
Sbjct: 3288 VFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAALDRE-----EVPHY 3342
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L VQA+ +P ++ V I + D+NDN P F +++ + E P G SVLQ++ TD
Sbjct: 3343 SLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSSVLQLVVTD 3402
Query: 333 KDQGENG-EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+D NG F++ + + + F +D + G L++ + H L+++V
Sbjct: 3403 RDTPRNGPPFSFHIVSGNQERRFHVD-QGGLLSLSAPLRKKVKGHHQLKIQV 3453
Score = 64.5 bits (150), Expect = 2e-08
Identities = 41/101 (40%), Positives = 56/101 (55%), Gaps = 4/101 (3%)
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-D 346
A+ARV IE+ D NDN P+F Y S+ EN P G SVLQV ATD D G+N TY L +
Sbjct: 405 AEARVVIEVKDENDNSPQFASPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALAN 464
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKET 386
F+I P +G ++ LD E ++V+A ++
Sbjct: 465 SGPSPFTIHPFTGVISTSGH--LDYELMRRRYHLRVWASDS 503
Score = 64.1 bits (149), Expect = 3e-08
Identities = 98/413 (23%), Positives = 169/413 (40%), Gaps = 54/413 (13%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPE+ G + + +A+D D G N I Y + + F I+
Sbjct: 2022 VIPESSEPGDVLYQASAVDGDLGENASILYSLEEDYSL---------------FRIDPHA 2066
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + + R L E+ ++ L + A+D G + + + ++ ++ N PVF+ Y V E
Sbjct: 2067 GDISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQVRNQSSPVFQTLLYPLKVPE 2126
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ V A + D L Y +Q + F I TGVL+V LD E++ +
Sbjct: 2127 NIPPFTTILHVQARNPD---GYRLVYNLQEENASKHFHIDFKTGVLTVTDPLDYESQRAH 2183
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPEADELSNHNFE 1174
+LTV A D+ DVNDN+P F A+ ++ P
Sbjct: 2184 VLTVRASDS--VTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVG--------T 2233
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDF--IGNGNGLILYSL---PQRKNQQNL-- 1227
SV+ + N + + + N+T+F I G+I+ + NQ +L
Sbjct: 2234 SVVQVSASDGDSGRNRDLTFHMLRTERNETEFFDIDPHTGVIVTKQVLDHEGTNQFHLKI 2293
Query: 1228 -----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
G LSS A ++V V DV D + P F+S YE ++E ++ + +
Sbjct: 2294 RATDNGTAPLSSEASVLVNVTDVND-----NPPDFVSSQYEATLDEKAKCGHIVIKIQAS 2348
Query: 1283 --EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
+ + K++Y IL+ N+ R F I+ +G + R ++ Y + V
Sbjct: 2349 DPDSGDLNKLQYKILSGNE---GRYFNINQSSGIVSFSNVCRRNLEPFYNLTV 2398
Score = 62.9 bits (146), Expect = 7e-08
Identities = 46/167 (27%), Positives = 79/167 (47%), Gaps = 8/167 (4%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN-----TFVLQVQASQLNNPL 285
L Y ++SG+D LF +++ F + + + N + L V+A++ ++ L
Sbjct: 37 LDYSVVSGDDDDLFQAEALKVGDFCFLRVRTRSGNAALLNREVRDAYTLTVEATEKSSDL 96
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A+ +V + +LD ND P F Y++SI E+ SV+ V ATD D G N +F Y
Sbjct: 97 R-AKTKVLVRVLDANDLKPLFYPASYSVSIAEDAELRSSVVTVSATDADVGSNADFYYSF 155
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
F++DP +G TV L+ + V A++ + G
Sbjct: 156 TSRAHPFAVDPFTG--TVSLVRKLNHTRSQRYELTVLAEDRTKKISG 200
Score = 62.9 bits (146), Expect = 7e-08
Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
A V++ +LD+NDN P+ E Y +++EN P+ VL+V A D D G NG+ +Y L
Sbjct: 2944 ASVSVDVHVLDINDNSPQCEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSLHG 3003
Query: 348 PKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
P F ++ R+G L VLDREA + A +
Sbjct: 3004 PNADKFHLNYRTGELL--TLAVLDREAEPEYNLVAKATD 3040
Score = 61.3 bits (142), Expect = 2e-07
Identities = 117/483 (24%), Positives = 190/483 (39%), Gaps = 68/483 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E G +IK+ A D DSG +++Y+ LS + RYF IN+ G
Sbjct: 2332 LDEKAKCGHIVIKIQASDPDSGDLNKLQYKI----------LSGNE---GRYFNINQSSG 2378
Query: 1000 HVIVARSLPPESEFRLNIS-ALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEA 1057
V + E N++ A+ G V + + N H P FK++ Y + E A
Sbjct: 2379 IVSFSNVCRRNLEPFYNLTVAVSDGVFQKTARVNIDMLSTNKHSPSFKQSVYEAELAENA 2438
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ +V+ ++ A D D G ++ Y I D I G + LDRE + I
Sbjct: 2439 EVGTQVI-RLAAIDPDEGLYGSVDYTIINKLADEKLAIDS-DGQMVTTQPLDRENPAQRI 2496
Query: 1118 LT--VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ V+A+D G D NDN P+F A + + + + + +
Sbjct: 2497 IAVKVMAKDGG---GKVAFCTVRIILTDENDNVPQFAASE------YQVSIQSTVNKGSP 2547
Query: 1176 VMMIPVYKATIEENAPIGTTV--AKVFANDTDFIGNGNGLI-----LYSLPQR----KNQ 1224
V+ I Y A NA + TV A+ D I GL+ L + R K Q
Sbjct: 2548 VVHIMAYDADEGRNADVTYTVDEAEEATEDVIEINPFTGLVTVKDSLVGMENRIFNFKVQ 2607
Query: 1225 QNLG-LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
G LP ++T + V V +P EV + P F Y E+ E+ S+
Sbjct: 2608 ARDGSLPFYNATVPVQVRV--LPPEVPL---PQFSEPLYTFSAVEDAPVGTEIGSVRAA- 2661
Query: 1284 HYENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
N + Y +++ N + + + F +D +GTL L + D E Y++ V A+
Sbjct: 2662 --SNTPLIYSLVDGNTLENNKDKVFSLDEDSGTLVLQKPMDHERTKWYQIDVMAQGNHNG 2719
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQV 1401
+ + V + ++++DVNDN P F P + P G V
Sbjct: 2720 TAVASL----------------VSISIQVQDVNDNEPLFDAS--PYRAFLAENMPAGTTV 2761
Query: 1402 MQL 1404
+Q+
Sbjct: 2762 IQV 2764
Score = 60.5 bits (140), Expect = 3e-07
Identities = 39/123 (31%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ + + + V P +TA+A+V + + D+ND+ P+F ++I I E+ G + Q
Sbjct: 1976 ETDVYEVVVMVRDTRTPPRTARAQVRVFIDDVNDSPPQFSNLPFSIVIPESSEPGDVLYQ 2035
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-KET 386
A D D GEN Y L++ F IDP +G +++ Q LD EA + + V A E
Sbjct: 2036 ASAVDGDLGENASILYSLEEDYSLFRIDPHAGDISL--QRPLDFEALNKYVLTVLAVDEG 2093
Query: 387 NPS 389
PS
Sbjct: 2094 EPS 2096
Score = 58.8 bits (136), Expect = 1e-06
Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Query: 1013 FRLNISALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+ L + A + +L V V V D ND P+F Y+ ++ E R + V ATD
Sbjct: 83 YTLTVEATEKSSDLRAKTKVLVRVLDANDLKPLFYPASYSVSIAEDAELRSSVVTVSATD 142
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
AD G NA+ Y + PF + P TG +S+ +L+ +Y LTV+A D
Sbjct: 143 ADVGSNADFYYSF--TSRAHPFAVDPFTGTVSLVRKLNHTRSQRYELTVLAED 193
Score = 58.0 bits (134), Expect = 2e-06
Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
L+RE RD Y +TV A + +V + + D ND P+F A+Y I E++++
Sbjct: 75 LNREVRDAYTLTVEATEKSSDLRAKT--KVLVRVLDANDLKPLFYPASYSVSIAEDAELR 132
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+ + + ATDAD G+NA F Y+ F F VD TG V + L+ + Y+L
Sbjct: 133 SSVVT---VSATDADVGSNADFYYS-FTSRAHPFAVDPFTGTVSLV-RKLNHTRSQRYEL 187
Query: 864 SLVARD 869
+++A D
Sbjct: 188 TVLAED 193
Score = 58.0 bits (134), Expect = 2e-06
Identities = 44/146 (30%), Positives = 65/146 (44%), Gaps = 8/146 (5%)
Query: 1014 RLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA-QYTRRVLGK------ 1066
RL +SA G + + V ++V D ND+ PVF++ Y + EA V G+
Sbjct: 1671 RLEVSASTVGGASSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLV 1730
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ A+DAD NA L Y I + F I P G +S+ +D E +Y +V RD+G
Sbjct: 1731 IQASDADRDANALLVYQILEPELLSVFSIDPSMGTISLLSAVDFEARAEYRFSVQVRDSG 1790
Query: 1127 X-XXXXXXXXXXXXXXXDVNDNSPKF 1151
D+ND +P F
Sbjct: 1791 EPCRYAAEPAKVTVRVLDLNDCAPHF 1816
Score = 55.2 bits (127), Expect = 1e-05
Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 9/150 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L + ++ + R F +D G + LD + + ++V
Sbjct: 1117 VWATDADASSEGKLSFHMLESH-RTHFDVDPKTGVVSTLSALDREEKEEHS-----VEVV 1170
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG--FSVLQVMATDKDQ 335
S +P ++ V I +LD NDN P+F ++I I E + V +++A D D+
Sbjct: 1171 VSDNGSPSLSSTTTVVIRVLDDNDNQPKFTDKLFHIKIPEQRRSAGEQEVYRMVARDDDR 1230
Query: 336 GENGEFTYQL-DDPKGAFSIDPRSGWLTVR 364
G N TY+L DD F IDP G +T R
Sbjct: 1231 GSNAAVTYRLQDDHSERFKIDPLLGVVTAR 1260
Score = 53.6 bits (123), Expect = 4e-05
Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 12/150 (8%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK-TAQARVEIELLDLN 300
++FS+D +G + +E D +A + V A+ L+ ++ VE+ + D N
Sbjct: 2796 EMFSIDEESGWITTTQEADCEA-----VRVYRFSVVATDNGGGLRLSSSVLVEVTVTDEN 2850
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG-ENGEFT-YQLD-DPKGAFSIDPR 357
DN P+F ++ Y S+VEN G ++ + D D EN T Y D DP G F+I +
Sbjct: 2851 DNPPKFSLEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITDGDPLGHFAIIQQ 2910
Query: 358 S--GWLTVRNQTVLDREAHSSLRMKVYAKE 385
S GW + Q LDRE ++V A +
Sbjct: 2911 SEGGWGLILTQP-LDREVKDRHALRVMATD 2939
Score = 53.2 bits (122), Expect = 5e-05
Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V +LDAND P+F P++ Y S+ +A++ + + V A D D+G N Y
Sbjct: 96 LRAKTKVLVRVLDANDLKPLFYPAS-YSVSIAEDAELRSSVVTVSATDADVGSNADFYYS 154
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPS--ERRYSLAV 554
TS PF ++P TGTVS+ + R+ L V A D+ S ++ ++A
Sbjct: 155 F--TSR---AHPFAVDPFTGTVSLVRKLNHTRSQRYELTVLAEDRTKKISGVQKFGNVAK 209
Query: 555 VTIEVTRGTKGN 566
+T+ V + +K +
Sbjct: 210 ITVHVQKTSKAS 221
Score = 51.2 bits (117), Expect = 2e-04
Identities = 48/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 980 KLSADALEVKR-YFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVF 1034
KLS LE R +F ++ + G V +L E E + + D G+ L+ +V +
Sbjct: 1129 KLSFHMLESHRTHFDVDPKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIR 1188
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYT--RRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
V D ND+ P F ++ + E + + + + ++ A D D G NA +TY +Q D
Sbjct: 1189 VLDDNDNQPKFTDKLFHIKIPEQRRSAGEQEVYRMVARDDDRGSNAAVTYRLQ-DDHSER 1247
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F+I PL GV++ G D + ILTV A D G
Sbjct: 1248 FKIDPLLGVVTARG--DFWPGNYSILTVKATDQG 1279
Score = 50.0 bits (114), Expect = 5e-04
Identities = 42/140 (30%), Positives = 63/140 (45%), Gaps = 34/140 (24%)
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
N ++ I+ PF I+PLTGV+ +LD E++ +Y V A NG
Sbjct: 357 NASFSIKDDPDGAPFRINPLTGVIVTTQKLDYESKRRYQFDVAA--NG----GEAEARVV 410
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK 1198
D NDNSP+F + P Y+A+++ENAP+G++V +
Sbjct: 411 IEVKDENDNSPQFAS--------------------------PSYEASLDENAPVGSSVLQ 444
Query: 1199 VFANDTDFIGNGNGLILYSL 1218
V A D D G N + Y+L
Sbjct: 445 VSATDAD--GGKNAFVTYAL 462
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 10/141 (7%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ-ARVEIELLDLNDN 302
FSLD +G L LE+ L DA TF L+V+A+ P A V + ++ L+D
Sbjct: 3097 FSLDEFSGLLRLERPLTPDAPP-----TFELKVKATDRGLPRHLYSIATVTVAVVSLDDY 3151
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P F Y + E+ G VL + A +D G Y++ + G F +D R+G
Sbjct: 3152 QPVFLSSEYTAQLPESFAVGSQVLSLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTGL 3211
Query: 361 LTVRNQTVLDREAHSSLRMKV 381
LT+ LD EA + + V
Sbjct: 3212 LTL--VAPLDFEASRTYYLSV 3230
Score = 42.7 bits (96), Expect = 0.075
Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 15/172 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+ L V V + D NDN PVF Y +K + G+++ KV A +P + +
Sbjct: 3237 QTLSDITTVMVNVTDVNDNAPVFEEGG-YRVEIKEDLPPGSLVMKVPAQEPPVFGGKVTA 3295
Query: 497 YDLQRTSN----LTITS-----PFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSE 547
D SN +I S F I+P +G +SVA + L+ + Q A+ +
Sbjct: 3296 SDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAA--LDREEVPHYSLTVQAADGGD 3353
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
S A++ + +T + P P F + + +G+SV Q+ V D
Sbjct: 3354 PPLSSAIL-VTITVADVNDNP--PIFSRVNHSLLLQEGEPVGSSVLQLVVTD 3402
Score = 42.3 bits (95), Expect = 0.099
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV-------L 326
L+V AS + ++ V I + D NDN P F Y I E G V L
Sbjct: 1672 LEVSASTVGGA--SSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPL 1729
Query: 327 QVMATDKDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+ A+D D+ N YQ+ +P+ FSIDP G T+ + +D EA + R V +
Sbjct: 1730 VIQASDADRDANALLVYQILEPELLSVFSIDPSMG--TISLLSAVDFEARAEYRFSVQVR 1787
Query: 385 ET 386
++
Sbjct: 1788 DS 1789
Score = 40.7 bits (91), Expect = 0.30
Identities = 19/46 (41%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 1434 NGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAAL 1479
+ + + ATD+D+G NAD Y + P FA+DP +GTV +V L
Sbjct: 133 SSVVTVSATDADVGSNADFYYSFTSRAHP-FAVDPFTGTVSLVRKL 177
Score = 40.7 bits (91), Expect = 0.30
Identities = 47/168 (27%), Positives = 68/168 (40%), Gaps = 17/168 (10%)
Query: 509 SPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
+PF+INP TG + + E + D AN E A V IEV K
Sbjct: 369 APFRINPLTGVIVTTQKLDYESKRRY---QFDVAANGGEAE---ARVVIEV----KDEND 418
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERS 626
+ P F YE + N +G+SV Q+ DA + V+Y L + PF + +
Sbjct: 419 NSPQFASPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANSGPS--PFTIHPFT 476
Query: 627 GVITVVDDLS-RYNRPMYDFEAVALQENANLSIVTN--ATVHVVDVND 671
GVI+ L R Y A + S V+ T+ + +VND
Sbjct: 477 GVISTSGHLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVND 524
Score = 39.9 bits (89), Expect = 0.53
Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 8/117 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D+G + Y L N K F L+ G L LD +AE +
Sbjct: 2984 VSAVDPDVGANGQVSYSLHGPNADK-FHLNYRTGELLTLAVLDREAEPEYN-------LV 3035
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A + ++ Q+ + + + D+NDN P F Y +++ +N + + A D D
Sbjct: 3036 AKATDGGGRSCQSDILLMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAKDPD 3092
Score = 36.7 bits (81), Expect = 4.9
Identities = 13/37 (35%), Positives = 25/37 (67%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+++ +S+++ ++DVNDN P+F +PY + E P G
Sbjct: 2722 VASLVSISIQVQDVNDNEPLFDASPYRAFLAENMPAG 2758
Score = 36.3 bits (80), Expect = 6.5
Identities = 34/183 (18%), Positives = 79/183 (43%), Gaps = 12/183 (6%)
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAG 694
L+R R Y A +++++L T V V+D ND + + ++S I ++
Sbjct: 75 LNREVRDAYTLTVEATEKSSDLRAKTKVLVRVLDANDLKPLFYPASYSVSI--AEDAELR 132
Query: 695 AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRM 754
+++ + T+ + + N F D GT+ + L+ + Y +
Sbjct: 133 SSVVTVSATD-ADVGSNADFYYSFTSRAHPFAVDPFT----GTVSLVRKLNHTRSQRYEL 187
Query: 755 TVIAEFNKGVISG----AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN 810
TV+AE ISG + ++T++++ + PV + + + + K+ +++++
Sbjct: 188 TVLAEDRTKKISGVQKFGNVAKITVHVQKTSKASPVISQVS-KPVVSADGKVTVDVQVEA 246
Query: 811 IIK 813
+K
Sbjct: 247 GVK 249
>UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35;
Euteleostomi|Rep: FAT tumor suppressor homolog 4 - Homo
sapiens (Human)
Length = 3222
Score = 145 bits (351), Expect = 9e-33
Identities = 229/923 (24%), Positives = 385/923 (41%), Gaps = 119/923 (12%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S+ +++T+LD NDN P+F + + + N ++ V A+D D G NG + Y++
Sbjct: 949 SYEKLDITVLDVNDNAPIF-KEDPFISEILENLSPRKIL-TVSAMDKDSGPNGQLDYEIV 1006
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
N + + F IN TG + E + L +++SD+ +PS+ ++ I
Sbjct: 1007 ---NGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDK-GSPSQSTSVKVMINI- 1061
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY---E 615
N P A V N +G +V ++ +D D+ + + Y +
Sbjct: 1062 --LDENDNAPRFSQIFSAH----VPENSPLGYTVTRVTTSD----EDIGINAISRYSIMD 1111
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+PF + +G I + L+R + Y A ++ ++ T+ T+ V D+ND
Sbjct: 1112 ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSA--HDSGWTVSTDVTIFVTDINDNAPR 1169
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ ++ + E G+ + Q+F T+ G V + I +Q + A
Sbjct: 1170 FSRTSYYLDCPELTE--IGSKVTQVFATDPDE---GSNGQVFYFIKSQSEYFR--INATT 1222
Query: 736 GTIFTQKPLDREKR------DVYRMT-VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G IF ++ L + ++ R + ++ ++G S VTI I D NDN P F
Sbjct: 1223 GEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFL 1282
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y + +N K+GT K+ + D D G N+ Y + D + G K
Sbjct: 1283 KSKYFTPVTKNVKVGT--KLIRVTAIDDKDFGLNSEVEYFISN--------DNHLGKFK- 1331
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
LD DTG +S + LI D N N I +K + +
Sbjct: 1332 ----LDN-------------DTGWISVASSLI---SDLNQNF----FITVTAKDKGNPPL 1367
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
T T+ E +N + Q IPE+ IG+ + ++A D D+ +NG I+Y
Sbjct: 1368 SSQATVHITVTE---ENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKY 1424
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNL- 1025
+S + F IN G + +A++L E + + ISA+DGG +
Sbjct: 1425 SISSG-------------NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVA 1471
Query: 1026 -NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
SV V V DVND+ PVF Y V E + + ++ATDAD G NA + Y +
Sbjct: 1472 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 1531
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
Q SD+DL F I P TGV++ G LD ET+ Y LTV A N
Sbjct: 1532 QSSDSDL-FVIDPNTGVITTQGFLDFETKQSYHLTVKA-FNVPDEERCSFATVNIQLKGT 1589
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
N+ P+F + +L + E+S + ++ V+ A+ + G +F N
Sbjct: 1590 NEYVPRFVS--KLYYF------EISEAAPKGTIVGEVF-ASDRDLGTDGEVHYLIFGNSR 1640
Query: 1205 D---FIGNGNGLILYS-LPQRKNQQNLGLPSLSST--AILMVTVADVPDEV---EMSDKP 1255
I G I S + R+ ++ + L L+ +I + +V V + +D P
Sbjct: 1641 KKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPP 1700
Query: 1256 VFISRYYELEIEENV--NAPVELVSLNLTEHYENF-KMRYYILNENDTDIRRTFVIDPRN 1312
+F Y ++I E V V VS ++ ++ + Y+I + N+ F I+P+
Sbjct: 1701 IFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENG---AFSINPQT 1757
Query: 1313 GTLYLVRSPDREVKDTYEVIVRA 1335
G + + DRE Y + V A
Sbjct: 1758 GQITVTAELDRETLPIYNLSVLA 1780
Score = 130 bits (314), Expect = 3e-28
Identities = 130/477 (27%), Positives = 212/477 (44%), Gaps = 39/477 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VE+TL D NDN PVF P+++ + +++ N G+ I ++ A+D D G N +V Y + ++
Sbjct: 24 VEITLQDINDNPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGAD 82
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F+I+P +G + E R ++L V A D S+ R ++ V +
Sbjct: 83 ----DSFRIDPESGDLIATRRLDRERRSKYSLLVRA-DDGLQSSDMRINITVSDV----- 132
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPF 620
P F Y F + + G+ V I +D+ +++Y + E+G+ F
Sbjct: 133 ----NDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGI-F 187
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+ +GV + L Y Y V ++ +++DVND + +
Sbjct: 188 FLNPITGVFNLT-RLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNS 246
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+S + EN + +F N++ + + IA+ D + ++G +
Sbjct: 247 YSTSLM---ENLPVGSTVLVF--NVTDADDGINSQLTYSIAS-GDSLGQFTVDKNGVLKV 300
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISG--AGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
K LDRE + Y + V + + QV+I + D NDNPP F +I E
Sbjct: 301 LKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT-YIPE 359
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
N+ I T + +ATD D G N+ YTL F + G V+ G+ LDRE+
Sbjct: 360 NTPIDTVVFK---AQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGE-LDREEV 415
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
Y L++VA D G LSS E+++M+ D NDN P F Q KV I+ T L GT
Sbjct: 416 SNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQ--ALYKVEINENT-LTGT 469
Score = 128 bits (308), Expect = 2e-27
Identities = 129/471 (27%), Positives = 209/471 (44%), Gaps = 44/471 (9%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ +V V ++D NDN+PVF+ S+ Y ++ NA GT + + A D D G N ++ Y +Q
Sbjct: 1475 YCSVTVNVIDVNDNSPVFL-SDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQS 1533
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEV 559
+ + F I+PNTG ++ E + + L V+A + P E R S A V I++
Sbjct: 1534 SD----SDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNV---PDEERCSFATVNIQL 1586
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEG 617
KG +P F+ Y F + GT VG++ + D +V Y L+ G
Sbjct: 1587 ----KGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHY-LIFGNSRK 1641
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F + +++G I V L R + +A N + A + V VN V +
Sbjct: 1642 KGFQINKKTGQIYVSGILDREKEERVSLKVLA----KNFGSIRGADIDEVTVN----VTV 1693
Query: 678 KGAHSPIIFHVK----ENSAGAAIGQIFHTNMSSIYGNGT----GNVRFLIANQQDVTDD 729
A+ P IF + + S G IG H S + + + + I + +
Sbjct: 1694 LDANDPPIFTLNIYSVQISEGVPIGT--HVTFVSAFDSDSIPSWSRFSYFIGSGNENGAF 1751
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ G I LDRE +Y ++V+A + G S G + + +ED NDN P+
Sbjct: 1752 SINPQTGQITVTAELDRETLPIYNLSVLA-VDSGTPSATGSASLLVTLEDINDNGPML-- 1808
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKF 848
EG +MEN + GT + +++TD D N F Y L G +T V
Sbjct: 1809 TVSEGEVMENKRPGTLVM---TLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLS 1865
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+DRE+ + LS+V +D+G +SS + I + D+NDN + +E
Sbjct: 1866 TTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVE 1916
Score = 126 bits (303), Expect = 6e-27
Identities = 127/460 (27%), Positives = 202/460 (43%), Gaps = 32/460 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV-DPDLGQNGMVLY 497
L+S V + ++D+NDN P F+ S Y + N KVGT + +V A+ D D G N V Y
Sbjct: 1261 LISETTVTINIVDSNDNAPQFLKSK-YFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY 1319
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVE-ASDQPANPSERRYSLAVVT 556
+ ++L FK++ +TG +SVA S I + F+ + NP S A V
Sbjct: 1320 FISNDNHL---GKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQATVH 1374
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGY 614
I VT P+F + + + IG+ V + R DA + Y + G
Sbjct: 1375 ITVTE----ENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGN 1430
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDER 673
EEG+ FA+ +G++T+ L ++ A+ + + TV+V+DVND
Sbjct: 1431 EEGI-FAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNS 1489
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V L + P + EN+ + H N + +GT V D +
Sbjct: 1490 PVFLSDDYFPTVL---ENAPSGT--TVIHLNATDA-DSGTNAVIAYTVQSSDSDLFVIDP 1543
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I TQ LD E + Y +TV A FN V I ++ N+ P F Y
Sbjct: 1544 NTGVITTQGFLDFETKQSYHLTVKA-FNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYY 1602
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDS 852
I E + GT + + A+D D GT+ Y +FG K+ F +++ TG + ++
Sbjct: 1603 FEISEAAPKGTIV---GEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQI-YVSGI 1658
Query: 853 LDREKKIMYKLSLVARDTGGLS----SEAELIIMIGDEND 888
LDREK+ L ++A++ G + E + + + D ND
Sbjct: 1659 LDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND 1698
Score = 123 bits (297), Expect = 3e-26
Identities = 118/461 (25%), Positives = 192/461 (41%), Gaps = 35/461 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + LLD NDN P F+ L + N + TV+ K +A DPD G N + Y L
Sbjct: 331 STAQVSIILLDVNDNPPTFLSPKLTY--IPENTPIDTVVFKAQATDPDSGPNSYIEYTLL 388
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + F I G V + E + L V A+D+ + V+ ++
Sbjct: 389 NP----LGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLD 444
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
+ P F A Y+ + N GT + Q+ D E V Y +++G
Sbjct: 445 INDNN-------PIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNG-NT 496
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVDVNDERGV 675
F ++ +G ITV L R P Y A + T+ ++ ++D+ND V
Sbjct: 497 NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPV 556
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
SP +V EN + G+ + L +D + ++
Sbjct: 557 F---ELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNED--NAFTLSAS 611
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + LDRE ++ + + + A + G + G + + ++D NDN P F Y
Sbjct: 612 GELGVTQSLDRETKERFVLMITAT-DSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTT 670
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I E++ GT++ ++ A+DAD NA+ + G G F ++ +TG + LDR
Sbjct: 671 IPEDAPTGTDVL---LVNASDADASKNAVI--RIIG-GNSQFTINPSTGQI-ITSALLDR 723
Query: 856 EKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEF 893
E K Y L +V D G LSS +++ + D NDN P F
Sbjct: 724 ETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRF 764
Score = 118 bits (284), Expect = 1e-24
Identities = 122/464 (26%), Positives = 205/464 (44%), Gaps = 38/464 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + + +T+ D ND+ P F +Y F + + G+++ + A D D G NG + Y +
Sbjct: 121 SDMRINITVSDVNDHTPKF-SRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVN 179
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
I F +NP TG ++ E + + L V A D + R ++ +
Sbjct: 180 EDDEDGI---FFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVN 236
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
+ P P F Y + N+ +G++V V DA + + ++Y + G
Sbjct: 237 -------DNP--PIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSL 287
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDF--EAVALQENANLSIVTNATVHVV--DVNDE 672
G F V+ ++GV+ V+ L R ++ Y+ + L + + A V ++ DVND
Sbjct: 288 G-QFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDN 345
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L SP + ++ EN+ + +F + + + + N I
Sbjct: 346 PPTFL----SPKLTYIPENTPIDTV--VFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGT 399
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
DG + LDRE+ Y +TV+A +KG S + +V + + D NDN P+F A Y
Sbjct: 400 I-DGEVRLTGELDREEVSNYTLTVVAT-DKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 457
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+ I EN+ GT+I + A D DEGTN Y + G + F +D TG + +
Sbjct: 458 KVEINENTLTGTDIIQ---VFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAIT-VAK 513
Query: 852 SLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEF 893
LDREK Y L++ A D G + + + I++ D ND P F
Sbjct: 514 PLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVF 557
Score = 117 bits (282), Expect = 2e-24
Identities = 113/419 (26%), Positives = 183/419 (43%), Gaps = 33/419 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V +LD NDNNP+F + LY+ + N GT I +V A D D G NG V Y
Sbjct: 432 LSSSTEVVVMVLDINDNNPIFAQA-LYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYG 490
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ N F+I+ TG ++VA+ E + L V+A+D+ + P ++++V
Sbjct: 491 IV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVL 547
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG-IGTSVGQI--RVNDAFEQNDVSYDLLHG 613
+++ +P F +PY V N+G + ++ Q+ R +D + +SY L G
Sbjct: 548 LDIN-------DFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGG 600
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVND 671
E+ F + SG + V L R + + A ++ + ++ T++V+ DVND
Sbjct: 601 NEDNA-FTLSA-SGELGVTQSLDRETKERFVLMITAT-DSGSPALTGTGTINVIVDDVND 657
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
A+ I ++ G + N S + +R + N Q +
Sbjct: 658 NVPTFASKAYFTTI--PEDAPTGT---DVLLVNASDADASKNAVIRIIGGNSQFTINP-- 710
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I T LDRE +D Y + V+ + V + + D NDNPP F+H
Sbjct: 711 --STGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHP 768
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y I + G+ + + TDAD G N+ Y+L G E F +D G + G
Sbjct: 769 YVTHIPSPTLPGSFVFA---VTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAG 824
Score = 108 bits (259), Expect = 1e-21
Identities = 132/485 (27%), Positives = 199/485 (41%), Gaps = 69/485 (14%)
Query: 929 LDVDQLGPLFL------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
LDV+ P FL IPEN PI T + K A D DSG N I Y + + +K S
Sbjct: 340 LDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPL---GNKFS 396
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDV 1038
++ G V + L E S + L + A D G +L+ + V V V D+
Sbjct: 397 IGTID-----------GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDI 445
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
ND+ P+F + Y + E T + +V A D D G N + Y I +T+ F I +
Sbjct: 446 NDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSV 505
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
TG ++V LDRE Y LTV A D G D+ND P F EL
Sbjct: 506 TGAITVAKPLDREKTPTYHLTVQATDRG-STPRTDTSTVSIVLLDINDFVPVF----ELS 560
Query: 1159 EWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL--ILY 1216
+ + L +++ + N+ + + V D F + +G +
Sbjct: 561 PYSVNVPENLGTLP-RTILQVVARDDDRGSNSKL-SYVLFGGNEDNAFTLSASGELGVTQ 618
Query: 1217 SLPQRKNQQ--------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
SL + ++ + G P+L+ T + V V DV D V P F S+ Y I E
Sbjct: 619 SLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNV-----PTFASKAYFTTIPE 673
Query: 1269 NVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
+ +++ +N ++ + I+ N F I+P G + DRE KD
Sbjct: 674 DAPTGTDVLLVNASDADASKNAVIRIIGGNS-----QFTINPSTGQIITSALLDRETKDN 728
Query: 1329 YEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
Y ++V S E P++ V+V + DVNDN P+F + P V
Sbjct: 729 YTLVVVCS-DAGSPE------PLSS---------STSVLVTVTDVNDNPPRFQ--HHPYV 770
Query: 1389 TAIPT 1393
T IP+
Sbjct: 771 THIPS 775
Score = 105 bits (251), Expect = 1e-20
Identities = 124/455 (27%), Positives = 197/455 (43%), Gaps = 63/455 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ ENI G+ I++L A+D D G N + Y S AD F I+ G
Sbjct: 47 VEENIGDGSKIMQLTAMDADEGANALVTYTIIS---------GADDS-----FRIDPESG 92
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+I R L E S++ L + A DG +D + + + V DVNDH P F + Y+F++ E
Sbjct: 93 DLIATRRLDRERRSKYSLLVRADDGLQSSD-MRINITVSDVNDHTPKFSRPVYSFDIPED 151
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
++ + ATD D G N +TY + D D F ++P+TGV ++ LD E + YI
Sbjct: 152 TIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYI 211
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
LTV A D G DVNDN P F S +++ + +
Sbjct: 212 LTVRAEDGG---GQFTTIRVYFNILDVNDNPPIF-----------------SLNSYSTSL 251
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAI 1237
M EN P+G+TV VF N TD N + YS+ + +LG ++ +
Sbjct: 252 M---------ENLPVGSTVL-VF-NVTDADDGINSQLTYSI---ASGDSLGQFTVDKNGV 297
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEE-NVNAPVELVSLNLTEHYENF---KMRYY 1293
L V A + + V + ++ A V ++ L++ ++ F K+ Y
Sbjct: 298 LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYI 357
Query: 1294 ILNEN-DTDIRRTFVIDPRNG----TLYLVRSP--DREVKDTYEVIVRAERQKYSRELP- 1345
N DT + + DP +G Y + +P ++ T + VR + E+
Sbjct: 358 PENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSN 417
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ + VA D + +VVV + D+NDN+P F
Sbjct: 418 YTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIF 452
Score = 103 bits (248), Expect = 3e-20
Identities = 119/461 (25%), Positives = 187/461 (40%), Gaps = 32/461 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E L S +V VT+ D NDN P F + Y + S G+ + V D D+G N +
Sbjct: 742 EPLSSSTSVLVTVTDVNDNPPRF-QHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELH 800
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF-VEASDQPANPSERRYSLAVV 555
Y L + + F I+P G + +A P+ F V D + P + V
Sbjct: 801 YSLSGRN----SEKFHIDPLRGAI-MAAGPLNGASEVTFSVHVKDGGSFP---KTDSTTV 852
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
T+ NK D P F N + + V I + +SY + G
Sbjct: 853 TVRFV-----NKADFPKVRAKEQTFMFPENQPVSSLVTTI-TGSSLRGEPMSYYIASG-N 905
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERG 674
G F +++ +G +++ L Y A S + V+DVND
Sbjct: 906 LGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAP 965
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ P I + EN + I + + S G + + I N
Sbjct: 966 IF---KEDPFISEILENLSPRKILTVSAMDKDS---GPNGQLDYEIVNGNMENSFSINHA 1019
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I + +PLDREK Y +T I +KG S + +V I I DENDN P F +
Sbjct: 1020 TGEIRSVRPLDREKVSHYVLT-IKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSA 1077
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ ENS +G + + +D D G NA+ Y++ + F ++ +TG + I L+
Sbjct: 1078 HVPENSPLGYTVTR---VTTSDEDIGINAISRYSIM-DASLPFTINPSTGDI-VISRPLN 1132
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
RE Y++ + A D+G S ++ I + D NDN P F++
Sbjct: 1133 REDTDRYRIRVSAHDSGWTVS-TDVTIFVTDINDNAPRFSR 1172
Score = 102 bits (245), Expect = 7e-20
Identities = 99/351 (28%), Positives = 160/351 (45%), Gaps = 33/351 (9%)
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V +E+T + P P F + V N+G G+ + Q+ DA E + V+Y ++
Sbjct: 21 VFIVEITLQDINDNP--PVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII 78
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G ++ F ++ SG + L R R Y A + + N TV DVND
Sbjct: 79 SGADDS--FRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVS--DVND 134
Query: 672 ERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ +S F + E++ G+ + I T+ S G + +++ +D D I
Sbjct: 135 HTPKFSRPVYS---FDIPEDTIPGSLVAAILATDDDS---GVNGEITYIV--NEDDEDGI 186
Query: 731 AIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G + LD E + Y +TV AE G + +Y I D NDNPP+F
Sbjct: 187 FFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVY---FNILDVNDNPPIFS 243
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVK 847
+Y +MEN +G+ + + N+ TDAD+G N+ Y++ G+ F VD+N GV+K
Sbjct: 244 LNSYSTSLMENLPVGSTVLVFNV---TDADDGINSQLTYSIASGDSLGQFTVDKN-GVLK 299
Query: 848 FIGDSLDREKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEF 893
+ +LDRE + Y L + D +S A++ I++ D NDN P F
Sbjct: 300 VL-KALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 349
Score = 101 bits (241), Expect = 2e-19
Identities = 102/342 (29%), Positives = 166/342 (48%), Gaps = 30/342 (8%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-- 123
DL +I A ++ ++ V++ + DVNDN P FL +P + E TP F
Sbjct: 320 DLPQIPA--SRFTSTAQVSIILLDVNDNPPTFL-SPKLTYIPENTPIDTVVFKAQATDPD 376
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSD----VHYSI-VSGNDDGHFALESSH 178
GP+ I T+ L I D + T D +Y++ V D G +L SS
Sbjct: 377 SGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSST 436
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYEL 235
+ V++ VLD + + F + I++ L I A D D G +RY +
Sbjct: 437 EVVVM---VLDINDNNPIFAQALYKV--EINENTLTGTDIIQVFAADGDEGTNGQVRYGI 491
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
++GN + F +DSV G++ + K LD + + T+ L VQA+ + +T + V I
Sbjct: 492 VNGNTNQEFRIDSVTGAITVAKPLDRE-----KTPTYHLTVQATDRGSTPRTDTSTVSIV 546
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPN-GFSVLQVMATDKDQGENGEFTYQL--DDPKGAF 352
LLD+ND +P FE+ Y++++ ENL ++LQV+A D D+G N + +Y L + AF
Sbjct: 547 LLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAF 606
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
++ SG L V LDRE + + A ++ +P++ GT
Sbjct: 607 TLS-ASGELGVTQS--LDRETKERFVLMITATDSGSPALTGT 645
Score = 100 bits (239), Expect = 4e-19
Identities = 118/414 (28%), Positives = 175/414 (42%), Gaps = 46/414 (11%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F IPE+ G+ + + A D DSG+NG+I Y N + D + F +N
Sbjct: 146 FDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNED--------DEDGI-----FFLNPI 192
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G + R L E + + L + A DGG I V + DVND+ P+F Y+ ++
Sbjct: 193 TGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLM 252
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + TDAD G N+ LTY I D+ F + GVL V LDRE++
Sbjct: 253 ENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDK-NGVLKVLKALDRESQSF 311
Query: 1116 YILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y L V D DVNDN P F L + PE + F
Sbjct: 312 YNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF--LSPKLTY-IPENTPIDTVVF 368
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQNL----- 1227
++ P N+ I T+ N IG +G + L R+ N
Sbjct: 369 KAQATDP----DSGPNSYIEYTLLNPLGNKFS-IGTIDGEVRLTGELDREEVSNYTLTVV 423
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
G PSLSS+ ++V V D+ D + P+F Y++EI EN +++ + +
Sbjct: 424 ATDKGQPSLSSSTEVVVMVLDIND-----NNPIFAQALYKVEINENTLTGTDIIQVFAAD 478
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
E N ++RY I+N N + F ID G + + + DRE TY + V+A
Sbjct: 479 GDEGTNGQVRYGIVNGN---TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQA 529
Score = 93.5 bits (222), Expect = 4e-17
Identities = 101/356 (28%), Positives = 155/356 (43%), Gaps = 26/356 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
DE+ SF V + L N+ P FV S LY F + A GT++G+V A D DLG +G V
Sbjct: 1573 DEERCSFATVNIQLKGTNEYVPRFV-SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEV 1631
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPAN-PSERRYSLAV 554
Y + S F+IN TG + V S IL+ V N S R +
Sbjct: 1632 HYLIFGNSR---KKGFQINKKTGQIYV--SGILDREKEERVSLKVLAKNFGSIRGADIDE 1686
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF---EQNDVSYDLL 611
VT+ VT N P P F Y + V IGT V + D+ + SY +
Sbjct: 1687 VTVNVT-VLDANDP--PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIG 1743
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DV 669
G E G F++ ++G ITV +L R P+Y+ +A+ ++ S +A++ V D+
Sbjct: 1744 SGNENGA-FSINPQTGQITVTAELDRETLPIYNLSVLAV-DSGTPSATGSASLLVTLEDI 1801
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND G +L + V EN + + + N G + + + T
Sbjct: 1802 ND-NGPMLTVSEG----EVMENKRPGTLVMTLQSTDPDLPPN-QGPFTYYLLSTGPATSY 1855
Query: 730 IAIAEDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+++ G + T + +DRE+ D Y V + +S G +T+ D+NDNP
Sbjct: 1856 FSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVI--DQNDNP 1909
Score = 88.2 bits (209), Expect = 2e-15
Identities = 118/460 (25%), Positives = 194/460 (42%), Gaps = 41/460 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + D NDN P F S Y ++ +A GT + V A D D +N ++
Sbjct: 648 INVIVDDVNDNVPTFA-SKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRI------- 699
Query: 505 LTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ S F INP+TG + S + + L V SD A E S V + VT
Sbjct: 700 IGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSD--AGSPEPLSSSTSVLVTVT-- 755
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPF 620
+ P P F PY + S G+ V + V DA +++ Y L E F
Sbjct: 756 DVNDNP--PRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSE--KF 811
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
++ G I L+ + + +V +++ + + TV V VN ++
Sbjct: 812 HIDPLRGAIMAAGPLNGASEVTF---SVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAK 868
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIF 739
+F EN +++ + SS+ G + + IA+ ++ + I + G +
Sbjct: 869 EQTFMF--PENQPVSSL--VTTITGSSLRGEP---MSYYIASG-NLGNTFQIDQLTGQVS 920
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+PLD EK Y + + A + G + ++ I + D NDN P+F+ + I+EN
Sbjct: 921 ISQPLDFEKIQKYVVWIEAR-DGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILEN 979
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ + A D D G N Y + G + F ++ TG ++ + LDREK
Sbjct: 980 LSPRKILT----VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRP-LDREKV 1034
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQI 896
Y L++ + D G S + +MI DENDN P F+QI
Sbjct: 1035 SHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQI 1074
Score = 87.0 bits (206), Expect = 3e-15
Identities = 83/312 (26%), Positives = 134/312 (42%), Gaps = 19/312 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
+VT+ I D NDN P FL + Y V + G K I + A + V ++
Sbjct: 1266 TVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTK-LIRVTAIDDKDFGLNSEVEYFISND 1324
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF----ALESSHKPV----LLLRKVLDYDAG 193
+ F D +T V S++S + F A + + P+ + V + +
Sbjct: 1325 NHLGKFKLDN-DTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 1383
Query: 194 DKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
EF Q + A+ H + A D+D + ++Y + SGN+ +F+++S G
Sbjct: 1384 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGI 1443
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L L K LD + + + A +T V + ++D+NDN P F D Y
Sbjct: 1444 LTLAKALDYEL-----CQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYF 1498
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDR 371
+++EN P+G +V+ + ATD D G N Y + F IDP +G +T Q LD
Sbjct: 1499 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVIT--TQGFLDF 1556
Query: 372 EAHSSLRMKVYA 383
E S + V A
Sbjct: 1557 ETKQSYHLTVKA 1568
Score = 86.2 bits (204), Expect = 6e-15
Identities = 50/173 (28%), Positives = 92/173 (53%), Gaps = 8/173 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G L YE+++GN FS++ G + + LD + + + +VL ++
Sbjct: 988 VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDRE-----KVSHYVLTIK 1042
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+S +P ++ +V I +LD NDN P F ++ + EN P G++V +V +D+D G
Sbjct: 1043 SSDKGSPSQSTSVKVMINILDENDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGI 1101
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
N Y + D F+I+P +G + + L+RE R++V A ++ +V
Sbjct: 1102 NAISRYSIMDASLPFTINPSTGDIVISRP--LNREDTDRYRIRVSAHDSGWTV 1152
Score = 85.8 bits (203), Expect = 8e-15
Identities = 88/330 (26%), Positives = 146/330 (44%), Gaps = 28/330 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPLTVPRGLTI 140
V + ++D+NDN P+F +TV+E G K + A G + + T+ G
Sbjct: 24 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADD 83
Query: 141 FKDIRAFDRDKPNTPNSDVH----YSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
I D T D YS++ DDG L+SS + + V D + +
Sbjct: 84 SFRIDPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINIT--VSDVNDHTPK 138
Query: 197 FQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
F + + I ++ + + AI D D GV + Y + ++ +F L+ + G
Sbjct: 139 FSRPVYSFD--IPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVF 196
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
L + LD + + ++L V+A T RV +LD+NDN P F ++ Y+
Sbjct: 197 NLTRLLDYEVQQY-----YILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFSLNSYST 249
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDR 371
S++ENLP G +VL TD D G N + TY + D G F++D ++G L V LDR
Sbjct: 250 SLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLK--ALDR 306
Query: 372 EAHSSLRMKVYAKETNPSVVGTFADSQRIA 401
E+ S + V + F + +++
Sbjct: 307 ESQSFYNLVVQVHDLPQIPASRFTSTAQVS 336
Score = 81.4 bits (192), Expect = 2e-13
Identities = 82/329 (24%), Positives = 139/329 (42%), Gaps = 23/329 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--I 124
+V G +S+ V V + D+NDN PIF Y V ++E T TG A
Sbjct: 422 VVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDE 481
Query: 125 GPSLTIPLTVPRGLT-----IFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSH 178
G + + + G T I A KP + + ++ V D G +
Sbjct: 482 GTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTS 541
Query: 179 KPVLLLRKVLDYDAGDK--EFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
++L + D+ + + + + + + + IL + A D D G + L Y L
Sbjct: 542 TVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTIL---QVVARDDDRGSNSKLSYVLF 598
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
GN+ F+L S +G L + + LD + + FVL + A+ +P T + + +
Sbjct: 599 GGNEDNAFTL-SASGELGVTQSLDRETKER-----FVLMITATDSGSPALTGTGTINVIV 652
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
D+NDN+P F Y +I E+ P G VL V A+D D +N ++ F+I+P
Sbjct: 653 DDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA--VIRIIGGNSQFTINP 710
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G + +LDRE + + V +
Sbjct: 711 STG--QIITSALLDRETKDNYTLVVVCSD 737
Score = 80.2 bits (189), Expect = 4e-13
Identities = 84/314 (26%), Positives = 140/314 (44%), Gaps = 25/314 (7%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTV 134
+S+ SV V + DVNDN P F PY + T G F + A IGP+ + ++
Sbjct: 744 LSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL 803
Query: 135 P-RGLTIFK--DIR-AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
R F +R A P S+V +S V D G F S + D+
Sbjct: 804 SGRNSEKFHIDPLRGAIMAAGPLNGASEVTFS-VHVKDGGSFPKTDSTTVTVRFVNKADF 862
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+ Q + + + + I G + Y + SGN F +D +
Sbjct: 863 PKVRAKEQTFMFPENQPVSSLVT------TITGSSLRGEPMSYYIASGNLGNTFQIDQLT 916
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + + + LD + + +V+ ++A P ++ +++I +LD+NDN P F+ D
Sbjct: 917 GQVSISQPLDFE-----KIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP 971
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
+ I+ENL + +L V A DKD G NG+ Y++ + + +FSI+ +G +R+
Sbjct: 972 FISEILENL-SPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATG--EIRSVRP 1028
Query: 369 LDRE--AHSSLRMK 380
LDRE +H L +K
Sbjct: 1029 LDREKVSHYVLTIK 1042
Score = 80.2 bits (189), Expect = 4e-13
Identities = 70/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F I E P GT + ++ A D D G +G++ Y + S+ K+ F IN++
Sbjct: 1603 FEISEAAPKGTIVGEVFASDRDLGTDGEVHY-----LIFGNSR--------KKGFQINKK 1649
Query: 998 HGHVIVARSLPPESEFRLNISAL--DGGNLN----DNISVRVFVKDVNDHFPVFKKTWYN 1051
G + V+ L E E R+++ L + G++ D ++V V V D ND P+F Y+
Sbjct: 1650 TGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYS 1708
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+ E + V A D+D + + +YFI + + F I+P TG ++V ELDR
Sbjct: 1709 VQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDR 1768
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD-ELLEWKHP 1163
ET Y L+V+A D+G D+NDN P + E++E K P
Sbjct: 1769 ETLPIYNLSVLAVDSG-TPSATGSASLLVTLEDINDNGPMLTVSEGEVMENKRP 1821
Score = 79.8 bits (188), Expect = 5e-13
Identities = 119/481 (24%), Positives = 193/481 (40%), Gaps = 75/481 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ P GT ++ +NA D D+ N IR + F IN G
Sbjct: 671 IPEDAPTGTDVLLVNASDADASKNAVIRI-----------------IGGNSQFTINPSTG 713
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+I + L E++ + L + D G+ L+ + SV V V DVND+ P F+ Y ++
Sbjct: 714 QIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHI 773
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+ V TDAD G N+ L Y + +++ F I PL G + G L+ +E
Sbjct: 774 PSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSE-KFHIDPLRGAIMAAGPLNGASEV 832
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+ +V +D G + PK A ++ + PE +S+
Sbjct: 833 TF--SVHVKDGGSFPKTDSTTVTVRFVNKA--DFPKVRAKEQ--TFMFPENQPVSS---- 882
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ--RKNQQNL----- 1227
++ + P+ +A +T I G + S P K Q+ +
Sbjct: 883 ---LVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEA 939
Query: 1228 ---GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN-APVELVSLNLTE 1283
G P SS L +TV DV D + + FIS EI EN++ + VS +
Sbjct: 940 RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFIS-----EILENLSPRKILTVSAMDKD 994
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
N ++ Y I+N N + +F I+ G + VR DRE Y + ++
Sbjct: 995 SGPNGQLDYEIVNGN---MENSFSINHATGEIRSVRPLDREKVSHYVLTIK--------- 1042
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
+ D VKV++ I D NDN+P+F ++ +P +P GY V +
Sbjct: 1043 --------SSDKGSPSQSTSVKVMINILDENDNAPRF---SQIFSAHVPENSPLGYTVTR 1091
Query: 1404 L 1404
+
Sbjct: 1092 V 1092
Score = 78.6 bits (185), Expect = 1e-12
Identities = 47/131 (35%), Positives = 72/131 (54%), Gaps = 5/131 (3%)
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
++ A ++ V I ++D NDNPPVF + + EN G++I + A DADEG NAL
Sbjct: 16 LAAAEVFIVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQ---LTAMDADEGANAL 72
Query: 825 FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
YT+ + F +D +G + LDRE++ Y L LV D G SS+ + I +
Sbjct: 73 VTYTIISGADDSFRIDPESGDL-IATRRLDRERRSKYSL-LVRADDGLQSSDMRINITVS 130
Query: 885 DENDNKPEFNQ 895
D ND+ P+F++
Sbjct: 131 DVNDHTPKFSR 141
Score = 74.9 bits (176), Expect = 2e-11
Identities = 101/374 (27%), Positives = 160/374 (42%), Gaps = 43/374 (11%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + ++D+ND+ PVF + VEE + ++ A DAD G NA +TY I S D
Sbjct: 24 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTI-ISGAD 82
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I P +G L LDRE KY L V A D DVND++PK
Sbjct: 83 DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDG----LQSSDMRINITVSDVNDHTPK 138
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FI 1207
F + + PE D + ++ AT +++ G V +D D F+
Sbjct: 139 FSR--PVYSFDIPE-DTIPG------SLVAAILATDDDSGVNGEITYIVNEDDEDGIFFL 189
Query: 1208 GNGNGLI-LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYEL 1264
G+ L L + QQ L + T V + +++D P+F Y
Sbjct: 190 NPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYST 249
Query: 1265 EIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+ EN+ ++ N+T+ + N ++ Y I + D F +D +NG L ++++ D
Sbjct: 250 SLMENLPVGSTVLVFNVTDADDGINSQLTYSIAS---GDSLGQFTVD-KNGVLKVLKALD 305
Query: 1323 REVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
RE + Y ++V+ +LP + P + T +V + + DVNDN P F +
Sbjct: 306 RESQSFYNLVVQV------HDLPQI--PASR-----FTS-TAQVSIILLDVNDNPPTFLS 351
Query: 1383 GNRPLVTAIPTTAP 1396
P +T IP P
Sbjct: 352 ---PKLTYIPENTP 362
Score = 73.3 bits (172), Expect = 5e-11
Identities = 85/333 (25%), Positives = 139/333 (41%), Gaps = 26/333 (7%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAPIGP 126
+R+ A + + VT+++ D+NDN P F T Y++ ELT G K +F P
Sbjct: 1141 IRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEG 1200
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSG----NDDGH-FALESSH--K 179
S + + + I A + N + Y V+G N + H F + SS K
Sbjct: 1201 SNGQVFYFIKSQSEYFRINATTGEIFN--KQILKYQNVTGFSNVNINRHSFIVTSSDRGK 1258
Query: 180 PVLLLRKVLD---YDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLR 232
P L+ + D+ D Q + + K + + + D+D G+ + +
Sbjct: 1259 PSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVE 1318
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y + + N F LD+ G + + L D N F + V A NP ++QA V
Sbjct: 1319 YFISNDNHLGKFKLDNDTGWISVASSLISDLNQN-----FFITVTAKDKGNPPLSSQATV 1373
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKG 350
I + + N + PEF + +I E+ G V V A D+D NG Y + + +G
Sbjct: 1374 HITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEG 1433
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
F+I+ +G LT+ LD E M + A
Sbjct: 1434 IFAINSSTGILTLAK--ALDYELCQKHEMTISA 1464
Score = 71.3 bits (167), Expect = 2e-10
Identities = 50/169 (29%), Positives = 83/169 (49%), Gaps = 10/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D G A + Y + +D LF +D G + + LD + + + + L V+
Sbjct: 1514 LNATDADSGTNAVIAYT-VQSSDSDLFVIDPNTGVITTQGFLDFETKQS-----YHLTVK 1567
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + + + A V I+L N+ +P F Y I E P G V +V A+D+D G
Sbjct: 1568 AFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGT 1627
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+GE Y + + K F I+ ++G + V +LDRE + +KV AK
Sbjct: 1628 DGEVHYLIFGNSRKKGFQINKKTGQIYVSG--ILDREKEERVSLKVLAK 1674
Score = 68.5 bits (160), Expect = 1e-09
Identities = 92/405 (22%), Positives = 165/405 (40%), Gaps = 42/405 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPY-HVTVDELTPTGEKAFIFLIAPIGPSLTIP 131
G S+Y + + + DVNDN PIF + P+ ++ L+P + GP+ +
Sbjct: 943 GFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLD 1002
Query: 132 LTVPRG-----LTI------FKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKP 180
+ G +I + +R DR+K + HY + + D +S+
Sbjct: 1003 YEIVNGNMENSFSINHATGEIRSVRPLDREKVS------HYVLTIKSSDKGSPSQSTSVK 1056
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
V++ +LD + F + A + D+D+G+ A RY ++ +
Sbjct: 1057 VMI--NILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDAS- 1113
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
F+++ G + + + L+ + + + ++V A ++ T V I + D+N
Sbjct: 1114 -LPFTINPSTGDIVISRPLNRE-----DTDRYRIRVSA---HDSGWTVSTDVTIFVTDIN 1164
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
DN P F Y + E G V QV ATD D+G NG+ Y + F I+ +G
Sbjct: 1165 DNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTG- 1223
Query: 361 LTVRNQTVLDRE---AHSSLRMKVYAKETNPSVVG-TFADSQRIAKWRRQPLETNAP-LE 415
+ N+ +L + S++ + ++ S G S+ NAP
Sbjct: 1224 -EIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFL 1282
Query: 416 KTTYVFP----DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
K+ Y P KVGTK + D++ +N EV +NDN+
Sbjct: 1283 KSKYFTPVTKNVKVGTKLIRVTAIDDKDFG-LNSEVEYFISNDNH 1326
Score = 68.5 bits (160), Expect = 1e-09
Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 12/181 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+DLG + Y LI GN RK F ++ G +++ LD + E + VL
Sbjct: 1618 VFASDRDLGTDGEVHY-LIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK--VLAK 1674
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ + V + +LD ND P F ++ Y++ I E +P G V V A D D
Sbjct: 1675 NFGSIRGA-DIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSI 1732
Query: 337 EN-GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVG 392
+ F+Y + + GAFSI+P++G +TV + LDRE + V A ++ PS G
Sbjct: 1733 PSWSRFSYFIGSGNENGAFSINPQTGQITVTAE--LDRETLPIYNLSVLAVDSGTPSATG 1790
Query: 393 T 393
+
Sbjct: 1791 S 1791
Score = 68.1 bits (159), Expect = 2e-09
Identities = 61/168 (36%), Positives = 83/168 (49%), Gaps = 13/168 (7%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAE--HNLQANTFVL-QVQA 278
D D G+ + L Y + SG+ F++D NG L + K LD +++ +NL L Q+ A
Sbjct: 268 DADDGINSQLTYSIASGDSLGQFTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPA 326
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S+ T+ A+V I LLD+NDN P F + I EN P V + ATD D G N
Sbjct: 327 SRF-----TSTAQVSIILLDVNDNPPTF-LSPKLTYIPENTPIDTVVFKAQATDPDSGPN 380
Query: 339 GEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y L +P G FSI G VR LDRE S+ + V A +
Sbjct: 381 SYIEYTLLNPLGNKFSIGTIDG--EVRLTGELDREEVSNYTLTVVATD 426
Score = 66.5 bits (155), Expect = 5e-09
Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 281 LNNPLKTAQAR-VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
L PL A+ VEI L D+NDN P F D ++++ EN+ +G ++Q+ A D D+G N
Sbjct: 12 LAQPLAAAEVFIVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANA 71
Query: 340 EFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
TY + +F IDP SG L + LDRE S + V A +
Sbjct: 72 LVTYTIISGADDSFRIDPESGDLIATRR--LDRERRSKYSLLVRADD 116
Score = 63.7 bits (148), Expect = 4e-08
Identities = 90/401 (22%), Positives = 159/401 (39%), Gaps = 51/401 (12%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVND-HFPVFKKTWY 1050
F I+ G ++ A L SE ++ DGG+ S V V+ VN FP +
Sbjct: 811 FHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQ 870
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F E Q ++ + + + ++Y+I + F+I LTG +S++ LD
Sbjct: 871 TFMFPENQPVSSLVTTITGSSL---RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDF 927
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E KY++ + ARD G DVNDN+P F D + ++ L N
Sbjct: 928 EKIQKYVVWIEARDGG-FPPFSSYEKLDITVLDVNDNAPIFKE-DPFI------SEILEN 979
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI--LYSLPQRK------ 1222
+ ++ + N + + ++ I + G I + L + K
Sbjct: 980 LSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVL 1039
Query: 1223 --NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
+ G PS S++ +M+ + D E + P F S+ + + E N+P+
Sbjct: 1040 TIKSSDKGSPSQSTSVKVMINILD-----ENDNAPRF-SQIFSAHVPE--NSPLGYTVTR 1091
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+T E+ + I + D F I+P G + + R +RE D Y + V A +
Sbjct: 1092 VTTSDEDIGIN-AISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW 1150
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ V+ D V + + D+NDN+P+F+
Sbjct: 1151 T---------VSTD-----------VTIFVTDINDNAPRFS 1171
Score = 54.0 bits (124), Expect = 3e-05
Identities = 55/219 (25%), Positives = 99/219 (45%), Gaps = 23/219 (10%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
T T+++ F L++ + I E +PIGT + ++A D DS + R+ +
Sbjct: 1688 TVNVTVLDANDPPIFTLNIYSVQ----ISEGVPIGTHVTFVSAFDSDS-IPSWSRFSY-- 1740
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDN 1028
+I + F IN + G + V L E+ + L++ A+D G + +
Sbjct: 1741 --FIGSGNENGA-------FSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGS 1791
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTYFIQPS 1087
S+ V ++D+ND+ P+ T V E + ++ + +TD D N TY++ +
Sbjct: 1792 ASLLVTLEDINDNGPML--TVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLST 1849
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ GVLS E+DRE + L+VV +D+G
Sbjct: 1850 GPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSG 1888
Score = 50.4 bits (115), Expect = 4e-04
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 31/147 (21%)
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYI 1294
I+ +T+ D+ D + PVF + +L +EEN+ +++ L + E N + Y I
Sbjct: 23 IVEITLQDIND-----NPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTI 77
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAED 1354
++ D R IDP +G L R DRE + Y ++VRA+
Sbjct: 78 ISGADDSFR----IDPESGDLIATRRLDRERRSKYSLLVRAD------------------ 115
Query: 1355 VLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+G+ D+++ + + DVND++PKF+
Sbjct: 116 --DGLQSSDMRINITVSDVNDHTPKFS 140
Score = 50.4 bits (115), Expect = 4e-04
Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 11/144 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D A +R +I GN + F+++ G + LD + + N T V+
Sbjct: 684 VNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLDRETKDNY---TLVVVCS 736
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE-NLPNGFSVLQVMATDKDQG 336
+ PL ++ + V + + D+NDN P F+ Y I LP F V V TD D G
Sbjct: 737 DAGSPEPLSSSTS-VLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSF-VFAVTVTDADIG 794
Query: 337 ENGEFTYQLDDPKG-AFSIDPRSG 359
N E Y L F IDP G
Sbjct: 795 PNSELHYSLSGRNSEKFHIDPLRG 818
Score = 45.2 bits (102), Expect = 0.014
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 17/171 (9%)
Query: 36 LAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIGAGL-NQISAYLSVTVYIEDVNDNV 94
L ++ + +D+ ++ KF+L D D G + + + L + ++ +TV +D N
Sbjct: 1313 LNSEVEYFISNDN--HLGKFKL--DNDTG--WISVASSLISDLNQNFFITVTAKD-KGNP 1365
Query: 95 PIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNT 154
P+ H+TV E E + S TIP + G +I + + A DRD
Sbjct: 1366 PLSSQATVHITVTE-----ENYHTPEFSQSHMSATIPESHSIG-SIVRTVSARDRDA--A 1417
Query: 155 PNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASG 205
N + YSI SGN++G FA+ SS +L L K LDY+ K + G
Sbjct: 1418 MNGLIKYSISSGNEEGIFAINSS-TGILTLAKALDYELCQKHEMTISAIDG 1467
Score = 40.7 bits (91), Expect = 0.30
Identities = 19/36 (52%), Positives = 23/36 (63%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ Y SVTV + DVNDN P+FL Y TV E P+G
Sbjct: 1473 TGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSG 1508
Score = 37.9 bits (84), Expect = 2.1
Identities = 18/43 (41%), Positives = 25/43 (58%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
QATD D G N+ I Y +LN +F+I + G VR+ L R+
Sbjct: 371 QATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDRE 413
>UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type receptor
1 precursor; n=45; Eukaryota|Rep: Cadherin EGF LAG
seven-pass G-type receptor 1 precursor - Homo sapiens
(Human)
Length = 3014
Score = 144 bits (350), Expect = 1e-32
Identities = 190/705 (26%), Positives = 306/705 (43%), Gaps = 98/705 (13%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD NDN P+FV S+ ++ ++ N +G + ++AVD D G+N + Y L T++
Sbjct: 551 VSVQVLDVNDNEPIFV-SSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTAS 609
Query: 505 L--------------TITSPFKINPNTGTVSV-AESPILEGRHALF-VEASDQPANPSER 548
T PF+I+ ++G ++V AE E H F VEA D + P
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
S+++ ++V N D P F YE + + +G+SV ++ D + ++Y
Sbjct: 670 STSVSITVLDV------NDND-PVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITY 722
Query: 609 DLLHGYEEGVPFAVEER--SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
L G FA+ + G+IT+ L Y A + S + ++V
Sbjct: 723 QLTGGNTRN-RFALSSQRGGGLITLALPLDYKQEQQYVLAVTA--SDGTRSHTAHVLINV 779
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQD 725
D N R V + +H + ++ G +I + S TG N R Q
Sbjct: 780 TDANTHRPVF-QSSHYTVSVS-EDRPVGTSIATL------SANDEDTGENARITYVIQDP 831
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
V + GT++T LD E + Y +T++A+ N G+ + + I I D NDN P
Sbjct: 832 VPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDN-GIPQKSDTTTLEILILDANDNAP 890
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENT 843
F Y+G I E++ T I + ATD D G N +YT G +G F ++ +
Sbjct: 891 QFLWDFYQGSIFEDAPPSTSILQ---VSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTS 947
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENS 900
GV++ LDRE +Y L +A D G LS+ E+ + I D NDN P F E
Sbjct: 948 GVIR-TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMF----EKD 1002
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
++ + E N G + +++ A D D+ GP I I G + LDL
Sbjct: 1003 ELELFVEE--NNPVGSVVAKIR-----ANDPDE-GPNAQIMYQIVEG-DMRHFFQLDL-- 1051
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL 1020
LNG +R + + D EV+R +V+ V+ A S P S ++I +
Sbjct: 1052 -LNGDLR-----------AMVELD-FEVRREYVL------VVQATSAPLVSRATVHILLV 1092
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA-QYTRRVLGKVDATDADFGQNAN 1079
D NDN V P F+ + N+ ++ + V+G + A D D + N
Sbjct: 1093 D---QNDNPPV----------LPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLN 1139
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
T F+Q ++ L + P TG L ++ +LD + ++ V D
Sbjct: 1140 YT-FVQGNELRL-LLLDPATGELQLSRDLDNNRPLEALMEVSVSD 1182
Score = 127 bits (306), Expect = 3e-27
Identities = 130/471 (27%), Positives = 212/471 (45%), Gaps = 38/471 (8%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
E +++ + S +V +T+LD NDN+PVF YE + +A VG+ + ++A D D
Sbjct: 658 EAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPT-YELRLNEDAAVGSSVLTLQARDRDA 716
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTG----TVSVAESPILEGRHALFVEASDQPANP 545
N ++ Y L T T + F ++ G T+++ E ++ L V ASD
Sbjct: 717 --NSVITYQL--TGGNT-RNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGT--- 768
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
R A V I VT P F + Y V + +GTS+ + ND E
Sbjct: 769 ---RSHTAHVLINVTDANTHR----PVFQSSHYTVSVSEDRPVGTSIATLSAND--EDTG 819
Query: 606 VSYDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNA 662
+ + + ++ VP F ++ SG + + +L N+ Y +A Q+N S T
Sbjct: 820 ENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMA-QDNGIPQKSDTTTL 878
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ ++D ND L + IF ++ +I Q+ T+ S G + +
Sbjct: 879 EILILDANDNAPQFLWDFYQGSIF--EDAPPSTSILQVSATDRDS---GPNGRLLYTFQG 933
Query: 723 QQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
D D I G I TQ+ LDRE VY + +A + ++ + I D N
Sbjct: 934 GDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDIN 993
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD 840
DN P+FE E F+ EN+ +G+ + I+A D DEG NA MY + G+ + F +D
Sbjct: 994 DNAPMFEKDELELFVEENNPVGSVVAK---IRANDPDEGPNAQIMYQIVEGDMRHFFQLD 1050
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
G ++ + + LD E + Y L +V + L S A + I++ D+NDN P
Sbjct: 1051 LLNGDLRAMVE-LDFEVRREYVL-VVQATSAPLVSRATVHILLVDQNDNPP 1099
Score = 99.5 bits (237), Expect = 6e-19
Identities = 122/489 (24%), Positives = 216/489 (44%), Gaps = 44/489 (8%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
+ + ++Y + + V + D ND++PVF S Y ++ N +VG + ++A D
Sbjct: 322 RVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSE-YRERVRENLEVGYEVLTIRASDR 380
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP 545
D N + Y + + F++N ++G VS E + L VEA+DQ NP
Sbjct: 381 DSPINANLRYRVLGGA----WDVFQLNESSGVVSTRAVLDREEAAEYQLLVEANDQGRNP 436
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN 604
+ A V IEV + + P F Y V +VG+ T+V +++ D + QN
Sbjct: 437 GPLS-ATATVYIEV----EDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQN 491
Query: 605 -DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA- 662
+ Y +L G G F + SG++ V++ L + Y ++ Q+ ++ ++
Sbjct: 492 AAIHYSILSGNVAG-QFYLHSLSGILDVINPLDFEDVQKYSL-SIKAQDGGRPPLINSSG 549
Query: 663 --TVHVVDVNDERGVLLKG-------AHSPI---IFHVKENSAGAAIGQIFHTNM----S 706
+V V+DVND + + + P+ + H++ A + H + S
Sbjct: 550 VVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTAS 609
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
+ G G+ + A D I G I LDRE+ + Y V A + G
Sbjct: 610 TFLGGGSAGPK-NPAPTPDFPFQIH-NSSGWITVCAELDREEVEHYSFGVEA-VDHGSPP 666
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+ V+I + D NDN PVF TYE + E++ +G+ + ++A D D N++
Sbjct: 667 MSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVL---TLQARDRD--ANSVIT 721
Query: 827 YTLF-GEGKEMFDV-DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
Y L G + F + + G + + LD +++ Y L++ A D G S A ++I +
Sbjct: 722 YQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD-GTRSHTAHVLINVT 780
Query: 885 DENDNKPEF 893
D N ++P F
Sbjct: 781 DANTHRPVF 789
Score = 98.3 bits (234), Expect = 1e-18
Identities = 116/437 (26%), Positives = 192/437 (43%), Gaps = 68/437 (15%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F P E+ +G++++ L A D D+ N I Y+
Sbjct: 678 LDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDA--NSVITYQLTGG-------- 727
Query: 982 SADALEVKRYFVINERHGHVIVARSLP----PESEFRLNISALDGGNLNDNISVRVFVKD 1037
+ F ++ + G ++ +LP E ++ L ++A DG + V + V D
Sbjct: 728 -----NTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTR-SHTAHVLINVTD 781
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
N H PVF+ + Y +V E + + + A D D G+NA +TY IQ D F I P
Sbjct: 782 ANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQ--DPVPQFRIDP 839
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
+G + ELD E + Y LT++A+DNG D NDN+P+F
Sbjct: 840 DSGTMYTMMELDYENQVAYTLTIMAQDNG-IPQKSDTTTLEILILDANDNAPQFL----- 893
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT---DF-IGNGNGL 1213
W + + S ++ V AT ++ P G + D DF I +G+
Sbjct: 894 --WDFYQGSIFEDAP-PSTSILQV-SATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGV 949
Query: 1214 ILYSLPQRKNQQNL------------GLPS-LSSTAILMVTVADVPDEVEMSDKPVFISR 1260
I +R +++N+ G P+ LS++ + VT+ D+ D + P+F
Sbjct: 950 I--RTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDIND-----NAPMFEKD 1002
Query: 1261 YYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
EL +EEN V + V + N + N ++ Y I+ + D+R F +D NG L +
Sbjct: 1003 ELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIV---EGDMRHFFQLDLLNGDLRAM 1059
Query: 1319 RSPDREVKDTYEVIVRA 1335
D EV+ Y ++V+A
Sbjct: 1060 VELDFEVRREYVLVVQA 1076
Score = 95.5 bits (227), Expect = 1e-17
Identities = 91/314 (28%), Positives = 136/314 (43%), Gaps = 31/314 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S+ SV++ + DVNDN P+F Y + ++E G + I
Sbjct: 663 GSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITY 722
Query: 133 TVPRGLTIFKDIRAFDRDK-------PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ G T + + R P + Y + DG SH +L+
Sbjct: 723 QLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDG----TRSHTAHVLIN 778
Query: 186 KVLDYDAGDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
V D + FQ V ++ + + I + A D+D G A + Y + +
Sbjct: 779 -VTDANTHRPVFQSSHYTVSVSEDRPVGTSIA---TLSANDEDTGENARITY--VIQDPV 832
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F +D +G+++ ELD + N A T + Q + + P K+ +EI +LD ND
Sbjct: 833 PQFRIDPDSGTMYTMMELDYE---NQVAYTLTIMAQDNGI--PQKSDTTTLEILILDAND 887
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRS 358
N P+F DFY SI E+ P S+LQV ATD+D G NG Y DD G F I+P S
Sbjct: 888 NAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTS 947
Query: 359 GWLTVRNQTVLDRE 372
G +R Q LDRE
Sbjct: 948 G--VIRTQRRLDRE 959
Score = 93.5 bits (222), Expect = 4e-17
Identities = 61/180 (33%), Positives = 98/180 (54%), Gaps = 11/180 (6%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + T LDRE ++ + + V A A Y +T+ ++D ND+ PVFE + Y
Sbjct: 303 GAVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTY-ITVLVKDTNDHSPVFEQSEYRER 361
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ EN ++G E+ I+A+D D NA Y + G ++F ++E++GVV LDR
Sbjct: 362 VRENLEVGYEVL---TIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVS-TRAVLDR 417
Query: 856 EKKIMYKLSLVA----RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
E+ Y+L + A R+ G LS+ A + I + DENDN P+F+ E+N V++ + LN
Sbjct: 418 EEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFS--EQNYVVQVPEDVGLN 475
Score = 91.9 bits (218), Expect = 1e-16
Identities = 121/449 (26%), Positives = 187/449 (41%), Gaps = 61/449 (13%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
IEV+ +N + + +PE++ + T ++++ A D D G N I Y
Sbjct: 447 IEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHY---------- 496
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRV 1033
S LS + V F ++ G + V L E ++ L+I A DGG +N + V V
Sbjct: 497 SILSGN---VAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSV 553
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--------- 1084
V DVND+ P+F + + V E + + A DAD G+NA L Y +
Sbjct: 554 QVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLG 613
Query: 1085 -------QPSDT-DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
P+ T D PF+I +G ++V ELDRE + Y V A D+G
Sbjct: 614 GGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHG-SPPMSSSTS 672
Query: 1137 XXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV 1196
DVNDN P F E + E + + + I G T
Sbjct: 673 VSITVLDVNDNDPVF--TQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGGNTR 730
Query: 1197 AKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGLP------SLSSTAILMVTVADVPDEV 1249
+ FA + G GLI +LP K +Q L + S TA +++ V D
Sbjct: 731 NR-FALSSQ---RGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDA---- 782
Query: 1250 EMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV 1307
+ +PVF S +Y + + E+ V + +S N + EN ++ Y I D F
Sbjct: 783 -NTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVI-----QDPVPQFR 836
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
IDP +GT+Y + D E + Y + + A+
Sbjct: 837 IDPDSGTMYTMMELDYENQVAYTLTIMAQ 865
Score = 86.6 bits (205), Expect = 5e-15
Identities = 67/218 (30%), Positives = 100/218 (45%), Gaps = 20/218 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+ +G ++ + A D DS +N +RY ++ A +V F +NE G
Sbjct: 362 VRENLEVGYEVLTIRASDRDSPINANLRY-----------RVLGGAWDV---FQLNESSG 407
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN----LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
V L E +E++L + A D G L+ +V + V+D ND++P F + Y
Sbjct: 408 VVSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQ 467
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E + +V ATD D GQNA + Y I + F + L+G+L V LD E
Sbjct: 468 VPEDVGLNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDV 527
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
KY L++ A+D G DVNDN P F
Sbjct: 528 QKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIF 565
Score = 83.8 bits (198), Expect = 3e-14
Identities = 53/163 (32%), Positives = 80/163 (49%), Gaps = 8/163 (4%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
+D + + Y+L GN R F+L S G + L LD + Q +VL V AS
Sbjct: 712 RDRDANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQ---YVLAVTAS--- 765
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
+ ++ A V I + D N + P F+ Y +S+ E+ P G S+ + A D+D GEN T
Sbjct: 766 DGTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARIT 825
Query: 343 YQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y + DP F IDP SG T+ LD E + + + A++
Sbjct: 826 YVIQDPVPQFRIDPDSG--TMYTMMELDYENQVAYTLTIMAQD 866
Score = 79.8 bits (188), Expect = 5e-13
Identities = 110/462 (23%), Positives = 186/462 (40%), Gaps = 45/462 (9%)
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV 520
P Y+ ++ N GT+I ++ A G+ V Y ++ + F+I+ TG V
Sbjct: 246 PMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAV 305
Query: 521 SVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPY 578
S E + H L V+A D P R + +T+ V K P F + Y
Sbjct: 306 STDSVLDRETKETHVLRVKAVDYSTPP---RSATTYITVLV----KDTNDHSPVFEQSEY 358
Query: 579 EFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLS 636
V N+ +G V IR +D ++ Y +L G + F + E SGV++ L
Sbjct: 359 RERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWD--VFQLNESSGVVSTRAVLD 416
Query: 637 RYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGA 695
R Y A + N ++ ++V DE + + + V E+
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNT 476
Query: 696 AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMT 755
A+ ++ T+ G + + I + + G + PLD E Y ++
Sbjct: 477 AVLRVQATDRDQ--GQNAA-IHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLS 533
Query: 756 VIAEFN--KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
+ A+ +I+ +G+ V++ + D NDN P+F + ++ ++EN +G + I+
Sbjct: 534 IKAQDGGRPPLINSSGV--VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVH---IQ 588
Query: 814 ATDADEGTNALFMY-------TLFGEGKE-----------MFDVDENTGVVKFIGDSLDR 855
A DAD G NA Y T G G F + ++G + + LDR
Sbjct: 589 AVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAE-LDR 647
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
E+ Y + A D G +SS + I + D NDN P F Q
Sbjct: 648 EEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQ 689
Score = 79.0 bits (186), Expect = 9e-13
Identities = 114/457 (24%), Positives = 187/457 (40%), Gaps = 41/457 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P GT I++L+A G ++ Y + ++ S+ YF I+ G V
Sbjct: 256 ENEPAGTLILQLHAHYTIEGEEERVSY-YMEGLFDERSR---------GYFRIDSATGAV 305
Query: 1002 IVARSLPPESEFR--LNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
L E++ L + A+D + + + V VKD NDH PVF+++ Y V E
Sbjct: 306 STDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVREN 365
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + A+D D NANL Y + D+ F+++ +GV+S LDRE +Y
Sbjct: 366 LEVGYEVLTIRASDRDSPINANLRYRVLGGAWDV-FQLNESSGVVSTRAVLDREEAAEYQ 424
Query: 1118 LTVVARDNGXX-XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L V A D G D NDN P+F + +++ + ++
Sbjct: 425 LLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQAT 484
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFAND----TDFIG--NGNGLILYSLPQRKNQQNLGLP 1230
A I + G + + + D I + + YSL K Q P
Sbjct: 485 DRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSL-SIKAQDGGRPP 543
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENF 1288
++S+ ++ V V DV D ++P+F+S ++ + ENV PV + + EN
Sbjct: 544 LINSSGVVSVQVLDVND-----NEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENA 598
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK---DTYEVIVRAERQKYSRELP 1345
++ Y ++ D TF+ G +PD + + + V AE + E+
Sbjct: 599 RLHYRLV-----DTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDR--EEVE 651
Query: 1346 HMIYPV-AEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
H + V A D V + + DVNDN P FT
Sbjct: 652 HYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFT 688
Score = 78.2 bits (184), Expect = 2e-12
Identities = 43/135 (31%), Positives = 71/135 (52%), Gaps = 4/135 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A + Y ++SGN F L S++G L + LD + ++Q + ++ Q
Sbjct: 481 VQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFE---DVQKYSLSIKAQ 537
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
PL + V +++LD+NDN P F + +++EN+P G+ V+ + A D D GE
Sbjct: 538 DGG-RPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGE 596
Query: 338 NGEFTYQLDDPKGAF 352
N Y+L D F
Sbjct: 597 NARLHYRLVDTASTF 611
Score = 70.9 bits (166), Expect = 2e-10
Identities = 83/350 (23%), Positives = 148/350 (42%), Gaps = 30/350 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V + + DAN + PVF S+ Y S+ + VGT I + A D D G+N + Y +Q
Sbjct: 774 HVLINVTDANTHRPVFQSSH-YTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDP- 831
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
F+I+P++GT+ E + + L + A D +L ++ ++
Sbjct: 832 ----VPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDAN- 886
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP 619
+ P F+ Y+ + + TS+ Q+ D + + Y G +
Sbjct: 887 ------DNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGD 940
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLL 677
F +E SGVI L R N +Y+ A+A+ + LS V ++D+ND +
Sbjct: 941 FYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFE 1000
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDG 736
K +F + N G+ + +I + + + I + D+ + +G
Sbjct: 1001 KDELE--LFVEENNPVGSVVAKIRANDPDE---GPNAQIMYQIV-EGDMRHFFQLDLLNG 1054
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+ LD E R Y + V A + ++S A ++ I + D+NDNPPV
Sbjct: 1055 DLRAMVELDFEVRREYVLVVQAT-SAPLVSRATVH---ILLVDQNDNPPV 1100
Score = 70.1 bits (164), Expect = 4e-10
Identities = 60/205 (29%), Positives = 98/205 (47%), Gaps = 11/205 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+D + A LRY ++ G +F L+ +G + LD + +A + L V+
Sbjct: 375 IRASDRDSPINANLRYRVLGGA-WDVFQLNESSGVVSTRAVLDRE-----EAAEYQLLVE 428
Query: 278 AS-QLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A+ Q NP +A A V IE+ D NDN P+F Y + + E++ +VL+V ATD+DQ
Sbjct: 429 ANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQ 488
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
G+N Y + + G F + SG L V N + SL +K P + +
Sbjct: 489 GQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSS 548
Query: 394 FADSQRIAKWR-RQPLETNAPLEKT 417
S ++ +P+ ++P + T
Sbjct: 549 GVVSVQVLDVNDNEPIFVSSPFQAT 573
Score = 67.3 bits (157), Expect = 3e-09
Identities = 45/152 (29%), Positives = 73/152 (48%), Gaps = 8/152 (5%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
L R F +DS G++ + LD + + T VL+V+A + P ++A + +
Sbjct: 287 LFDERSRGYFRIDSATGAVSTDSVLDRETKE-----THVLRVKAVDYSTPPRSATTYITV 341
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFS 353
+ D ND+ P FE Y + ENL G+ VL + A+D+D N Y+ L F
Sbjct: 342 LVKDTNDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQ 401
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++ SG V + VLDRE + ++ V A +
Sbjct: 402 LNESSG--VVSTRAVLDREEAAEYQLLVEAND 431
Score = 66.5 bits (155), Expect = 5e-09
Identities = 50/169 (29%), Positives = 79/169 (46%), Gaps = 9/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D G L Y G+D F ++ +G + ++ LD E+ N + L V
Sbjct: 914 VSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLD--RENVAVYNLWALAV 971
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
PL +A +++ +LD+NDN P FE D + + EN P G V ++ A D D+G
Sbjct: 972 DRGS-PTPL-SASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEG 1029
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N + YQ+ D + F +D +G +R LD E + V A
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNG--DLRAMVELDFEVRREYVLVVQA 1076
Score = 64.9 bits (151), Expect = 2e-08
Identities = 61/237 (25%), Positives = 107/237 (45%), Gaps = 17/237 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V ++VT+LD NDN P+F L E ++ N VG+V+ K++A DPD G N ++Y
Sbjct: 979 LSASVEIQVTILDINDNAPMFEKDEL-ELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQ 1037
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + F+++ G + E R + L V+A+ P S A V
Sbjct: 1038 IVEGD---MRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPL------VSRATVH 1088
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV-GQIRVNDAFEQNDVSYDLLHGYE 615
I + N P +PDF + + T V G I +D + ++Y + G E
Sbjct: 1089 ILLV-DQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLNYTFVQGNE 1147
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
+ ++ +G + + DL NRP+ V++ + + S+ T+ V + D+
Sbjct: 1148 LRL-LLLDPATGELQLSRDLDN-NRPLEALMEVSVSDGIH-SVTAFCTLRVTIITDD 1201
Score = 61.7 bits (143), Expect = 2e-07
Identities = 52/170 (30%), Positives = 81/170 (47%), Gaps = 16/170 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G A + Y+++ G+ R F LD +NG L ELD + +VL VQ
Sbjct: 1021 IRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRRE-----YVLVVQ 1075
Query: 278 ASQLNNPLKTAQARVEIELLDLNDN---LPEFEVDFYNISIVENLPNGFS---VLQVMAT 331
A+ PL ++A V I L+D NDN LP+F++ F N V N N F + + A
Sbjct: 1076 ATSA--PL-VSRATVHILLVDQNDNPPVLPDFQILFNN--YVTNKSNSFPTGVIGCIPAH 1130
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
D D ++ +T+ + +DP +G L + +R + + + V
Sbjct: 1131 DPDVSDSLNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSV 1180
Score = 47.2 bits (107), Expect = 0.003
Identities = 81/343 (23%), Positives = 130/343 (37%), Gaps = 37/343 (10%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI----GP 126
G +SA +V + +ED NDN P F + Y V V E G + + G
Sbjct: 433 GRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPE--DVGLNTAVLRVQATDRDQGQ 490
Query: 127 SLTIPLTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKP 180
+ I ++ G + D P YS+ + D G L +S
Sbjct: 491 NAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGV 550
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEP-IHAIDQDLGVGATLRYELISGN 239
V + +VLD + + F + + + +P I A+D D G A L Y L+
Sbjct: 551 VSV--QVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTA 608
Query: 240 DRKL---------------FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
L F N S ++ +LD E + + V+A +P
Sbjct: 609 STFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDRE---EVEHYSFGVEAVDHGSP 665
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
++ V I +LD+NDN P F Y + + E+ G SVL + A D+D N TYQ
Sbjct: 666 PMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSVITYQ 723
Query: 345 L--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
L + + F++ + G + LD + + V A +
Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD 766
Score = 39.1 bits (87), Expect = 0.92
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 9/97 (9%)
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-----PKGAFSIDPRSG 359
+F + Y +++ EN P G +LQ+ A +GE +Y ++ +G F ID +G
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 360 WLTVRNQTVLDREAHSS--LRMKVYAKETNPSVVGTF 394
V +VLDRE + LR+K T P T+
Sbjct: 304 --AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTY 338
>UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 2493
Score = 144 bits (349), Expect = 2e-32
Identities = 133/459 (28%), Positives = 208/459 (45%), Gaps = 27/459 (5%)
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
A NNP + S+ +A+VGTV+ V A DPD G NGM+ Y + + NL + F
Sbjct: 12 APTNNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYF 71
Query: 512 KINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPD 569
I+ TG ++ E RH V+A D PS Y +++T +
Sbjct: 72 SIDQITGVITTKRGLDREFLDRHFFRVKAED-GGEPSLEGY------MDLTINVLDVNDN 124
Query: 570 IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGVPFAVEERSG 627
P F Y + + IG V +R +DA +V Y +L+ + F++ E SG
Sbjct: 125 GPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSG 184
Query: 628 VITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
+TV+ L R P Y + A Q N S + ++DVND K +S I
Sbjct: 185 AVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATI- 243
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
+E+ + Q+ T ++ G+ G V F I + D+ +G + ++ LD
Sbjct: 244 --RED---VPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLD 298
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
E V+ + V A+ +KG V I + D NDN P F + ++ I EN +G E
Sbjct: 299 YEMIGVFNLLVTAQ-DKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE 357
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
++A D D GTN ++ F + F ++ENTG + I + LDREK + +
Sbjct: 358 FYR---VQAYDKDHGTNGEITFS-FMQNDLPFSINENTGGIS-IKEELDREKVPKFTFGI 412
Query: 866 VARDTGGLSSE--AELIIMIGDENDNKPEFNQIEENSKV 902
ARD G E A++ I + D NDN P+F+Q E ++ +
Sbjct: 413 KARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSI 451
Score = 143 bits (346), Expect = 4e-32
Identities = 128/464 (27%), Positives = 207/464 (44%), Gaps = 32/464 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +TLLD NDN P F Y S+ N++ GT + +VKA+DPD G +V Y + +S
Sbjct: 428 ITITLLDINDNPPKFSQEE-YHTSIAENSRWGTSVLQVKAIDPDSGPTNVV-YSIVSSSG 485
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F+INP G ++++ + +H S S S A+V + VT
Sbjct: 486 HDRC--FRINPQ-GLITLSCTLNYNTKHVYVFSVSASDGMLS----STALVYVNVT---- 534
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAV 622
+ P+F Y V + +GTSV + D ++ +SY + E F+V
Sbjct: 535 DSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE---FSV 591
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAH 681
+E +GVI L R Y FE A L + +H+ DVND V LK ++
Sbjct: 592 DETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSY 651
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFT 740
V+E+ G++ + S + + A+ D I + G I T
Sbjct: 652 EA---KVREDIRPG--GRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRT 706
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
KPLDRE Y +TV+A ++G G +V + +ED D+PP+FE YE + E++
Sbjct: 707 LKPLDRETIPEYELTVVAT-DQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDT 765
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ + +KA D MY++ G ++FD++ NTG ++ + LD E +
Sbjct: 766 PPRSPV---ITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTL-MKLDYETQS 821
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
Y+L+ V +E +++ + D NDN P N V+
Sbjct: 822 EYRLT-VRATLSPFFTETTVMVYLKDINDNTPVLEAFHMNINVQ 864
Score = 129 bits (311), Expect = 7e-28
Identities = 137/537 (25%), Positives = 234/537 (43%), Gaps = 42/537 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L ++++ + +LD NDN P+F N+Y + + +G + V+A D D G NG V
Sbjct: 105 EPSLEGYMDLTINVLDVNDNGPIF-ERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEV 163
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLA 553
Y + + S F I +G V+V + E + L V+A DQ P ++
Sbjct: 164 KYCILNSDG--DNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVK 221
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
+ ++V T P F Y + +V + V +R D + +V ++++
Sbjct: 222 ITLLDVNDCT-------PQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV 274
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDV 669
G + F++ +G + V L +++ V Q+ + TV + +DV
Sbjct: 275 SGNDMNF-FSINRINGEVRVKQKLDYEMIGVFNL-LVTAQDKGQPFLYNQTTVDIALIDV 332
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTD 728
ND + +I EN A +GQ F+ + +GT G + F Q D+
Sbjct: 333 NDNAPQFVSSHFQTMI---PENYA---VGQEFYRVQAYDKDHGTNGEITFSFM-QNDLPF 385
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I G I ++ LDREK + + A +KGV G Q+TI + D NDNPP F
Sbjct: 386 SIN-ENTGGISIKEELDREKVPKFTFGIKAR-DKGVPFKEGTAQITITLLDINDNPPKFS 443
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEG-TNALFMYTLFGEGKEMFDVDENTGVVK 847
Y I ENS+ GT + +KA D D G TN ++ F ++ G++
Sbjct: 444 QEEYHTSIAENSRWGTSVLQ---VKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQ-GLIT 499
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+ +L+ K +Y S+ A D G LSS A + + + D N + PEF + +++V +E
Sbjct: 500 -LSCTLNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEV---KE 554
Query: 908 TKLNGTAGFTII----EVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
GT+ T++ + K + + L P F + E + T L+ +D+
Sbjct: 555 DASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDT 611
Score = 109 bits (261), Expect = 8e-22
Identities = 125/452 (27%), Positives = 194/452 (42%), Gaps = 59/452 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++P+ + + A D D G NG++ +E +S + + +F IN +G
Sbjct: 243 IREDVPVNQLVTTVRATDCDQGSNGEVFFEI----------VSGNDMN---FFSINRING 289
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V V + L E F L ++A D G L + +V + + DVND+ P F + + +
Sbjct: 290 EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIP 349
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + +V A D D G N +T+ F+Q DLPF I+ TG +S+ ELDRE
Sbjct: 350 ENYAVGQEFYRVQAYDKDHGTNGEITFSFMQ---NDLPFSINENTGGISIKEELDREKVP 406
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
K+ + ARD G D+NDN PKF E H E S
Sbjct: 407 KFTFGIKARDKG-VPFKEGTAQITITLLDINDNPPKFSQ-----EEYHTSIAENSRWG-T 459
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGLILYSLPQRKNQQNLGLPSL 1232
SV+ + KA ++ P + V ++ D F N GLI S N +++ + S+
Sbjct: 460 SVLQV---KAIDPDSGPTNVVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSV 516
Query: 1233 SSTAILMVTVADVPDEVEMSD--KPVFISRYYELEIEENVNAPVELVSLNLTEH--YENF 1288
S++ ++ + A V V S+ P F R Y E++E+ + ++++ T+ N
Sbjct: 517 SASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 576
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
K+ Y I + F +D G + S DRE DTY V A +P +
Sbjct: 577 KISYSI-----ATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTAT----DHGIPQL- 626
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
K V + I DVNDN P F
Sbjct: 627 ------------KAKSFVYIHIADVNDNDPVF 646
Score = 94.7 bits (225), Expect = 2e-17
Identities = 121/484 (25%), Positives = 208/484 (42%), Gaps = 65/484 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT + ++A D DSG NG IRY + PS+ A YF I++ G
Sbjct: 29 VSEDAEVGTVVATVSASDPDSGSNGMIRYSMS------PSQNLMSAT----YFSIDQITG 78
Query: 1000 HVIVARSLPPESEFR--LNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ R L E R + A DGG +L + + + V DVND+ P+F++ Y ++
Sbjct: 79 VITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIP 138
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LPFEISPLTGVLSVNGELDRETED 1114
E + + V A+DAD G N + Y I SD D F I ++G ++V +LDRE
Sbjct: 139 EDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVP 198
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y L V A+D G DVND +P+F +
Sbjct: 199 TYTLQVQAQDQG-NPPRSATVTVKITLLDVNDCTPQF---------SKKVYSATIREDVP 248
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFA-NDTDF--IGNGNGLILYSLPQRKNQQNLGLPS 1231
++ +AT + G ++ + ND +F I NG + + Q+ + + +G+ +
Sbjct: 249 VNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEV--RVKQKLDYEMIGVFN 306
Query: 1232 LSSTA-------ILMVTVADVPDEVEMSDK-PVFISRYYELEIEENVNAPVELVSLNL-- 1281
L TA + T D+ ++++D P F+S +++ I EN E +
Sbjct: 307 LLVTAQDKGQPFLYNQTTVDIA-LIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYD 365
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
+H N ++ + + +ND F I+ G + + DRE + ++A
Sbjct: 366 KDHGTNGEITFSFM-QNDL----PFSINENTGGISIKEELDREKVPKFTFGIKAR----D 416
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQV 1401
+ +P EG ++ + + D+NDN PKF+ T+I + +G V
Sbjct: 417 KGVPFK---------EG----TAQITITLLDINDNPPKFS--QEEYHTSIAENSRWGTSV 461
Query: 1402 MQLK 1405
+Q+K
Sbjct: 462 LQVK 465
Score = 93.1 bits (221), Expect = 5e-17
Identities = 114/413 (27%), Positives = 183/413 (44%), Gaps = 42/413 (10%)
Query: 158 DVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL-FPE 216
D H+ V D G +LE L VLD + F+ I A+ K I F
Sbjct: 92 DRHFFRVKAEDGGEPSLEGYMD---LTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVL 148
Query: 217 PIHAIDQDLGVGATLRYELI-SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G ++Y ++ S D FS+ V+G++ + K+LD + + T+ LQ
Sbjct: 149 AVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDRE-----KVPTYTLQ 203
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA NP ++A V+I LLD+ND P+F Y+ +I E++P V V ATD DQ
Sbjct: 204 VQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQ 263
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
G NGE +++ + FSI+ +G + V+ + LD E + V A++
Sbjct: 264 GSNGEVFFEIVSGNDMNFFSINRINGEVRVKQK--LDYEMIGVFNLLVTAQDKGQ----P 317
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTY---VFPDK--VGTKTENIEYYDEQLMSFVNVEVT 448
F +Q + NAP +++ + P+ VG + ++ YD+ N E+T
Sbjct: 318 FLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD--HGTNGEIT 375
Query: 449 LLDANDNNPVFVPSNLYEFSMK---SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
++ P + N S+K KV +KA D G+ + T+ +
Sbjct: 376 FSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARD-----KGVPF--KEGTAQI 428
Query: 506 TIT------SPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSL 552
TIT +P K + S+AE+ G L V+A D + P+ YS+
Sbjct: 429 TITLLDINDNPPKFSQEEYHTSIAENS-RWGTSVLQVKAIDPDSGPTNVVYSI 480
Score = 88.6 bits (210), Expect = 1e-15
Identities = 113/424 (26%), Positives = 169/424 (39%), Gaps = 45/424 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT+++++ A+D DSG + +S + +++ L + +N
Sbjct: 451 IAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQGL-ITLSCTLNYNTK 509
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
HV V ++SA DG L+ V V V D N H P FK+ Y+ V+E
Sbjct: 510 HVYV-----------FSVSASDG-MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDAS 557
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYIL 1118
+ V ATD D G NA ++Y I T +P F + TGV+ G LDRE D Y
Sbjct: 558 LGTSVLTVLATDRDTGSNAKISYSIA---TLVPEFSVDETTGVIKTAGSLDREKVDTYRF 614
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
V A D+G DVNDN P F E K E V+
Sbjct: 615 EVTATDHGIPQLKAKSFVYIHIA-DVNDNDPVF--LKPSYEAKVREDIRPGGR----VIE 667
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQ----------QNL 1227
+ A I +NA I + A F I + G+I P + +
Sbjct: 668 VSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQ 727
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHY 1285
G P ++ + V + DV D + +KP+ YE+ + E+ +PV V +
Sbjct: 728 GTPPGQASVKVKVILEDVKDSPPLFEKPL-----YEVTVPEDTPPRSPVITVKAKSQDLS 782
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
M Y I+ N + F I+P G + + D E + Y + VRA + E
Sbjct: 783 PETGMMYSIVRGNSPQV---FDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFFTETT 839
Query: 1346 HMIY 1349
M+Y
Sbjct: 840 VMVY 843
Score = 80.6 bits (190), Expect = 3e-13
Identities = 76/248 (30%), Positives = 110/248 (44%), Gaps = 24/248 (9%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L+ TA + V N A + + + E+ +GT+++ + A D D+G N +I Y
Sbjct: 523 LSSTA-LVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYS 581
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NL 1025
+ V P F ++E G + A SL E +R ++A D G L
Sbjct: 582 IATLV---PE------------FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQL 626
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTY-F 1083
V + + DVND+ PVF K Y V E+ + RV+ +V A+DAD G+NA + Y F
Sbjct: 627 KAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVI-EVSASDADIGKNAQIIYSF 685
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
D F I G++ LDRET +Y LTVVA D G D
Sbjct: 686 ASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQG-TPPGQASVKVKVILED 744
Query: 1144 VNDNSPKF 1151
V D+ P F
Sbjct: 745 VKDSPPLF 752
Score = 80.2 bits (189), Expect = 4e-13
Identities = 98/413 (23%), Positives = 171/413 (41%), Gaps = 45/413 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPEN +G ++ A D D G NG+I + F +P F INE
Sbjct: 347 MIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQND-LP--------------FSINENT 391
Query: 999 GHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + L E +F I A D G + + + D+ND+ P F + Y+ ++
Sbjct: 392 GGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSI 451
Query: 1055 -EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E +++ VL +V A D D G + + S D F I+P G+++++ L+ T+
Sbjct: 452 AENSRWGTSVL-QVKAIDPDSGPTNVVYSIVSSSGHDRCFRINP-QGLITLSCTLNYNTK 509
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y+ +V A D D N ++P+F E K E L
Sbjct: 510 HVYVFSVSASDG----MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVK--EDASLGT--- 560
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKV---FAND--TDFIGNGNGLILYSLPQRKNQQNL- 1227
SV+ + NA I ++A + F+ D T I L + + +
Sbjct: 561 -SVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTAT 619
Query: 1228 --GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
G+P L + + + + +ADV D + PVF+ YE ++ E++ ++ ++ ++
Sbjct: 620 DHGIPQLKAKSFVYIHIADVND-----NDPVFLKPSYEAKVREDIRPGGRVIEVSASDAD 674
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ ++ D + TF ID G + ++ DRE YE+ V A Q
Sbjct: 675 IGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQ 727
Score = 77.0 bits (181), Expect = 4e-12
Identities = 69/236 (29%), Positives = 103/236 (43%), Gaps = 27/236 (11%)
Query: 930 DVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DV+ P+FL P E+I G +I+++A D D G N QI Y F S +
Sbjct: 638 DVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFAS---------N 688
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNL--NDNISVRVFVKDV 1038
D + F I+ G + + L E+ E+ L + A D G ++ V+V ++DV
Sbjct: 689 GDG---QGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDV 745
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
D P+F+K Y V E R + V A D + Y I ++ F+I+P
Sbjct: 746 KDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPN 805
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
TG + +LD ET+ +Y LTV A D+NDN+P AF
Sbjct: 806 TGAIQTLMKLDYETQSEYRLTVRA----TLSPFFTETTVMVYLKDINDNTPVLEAF 857
Score = 69.3 bits (162), Expect = 8e-10
Identities = 92/387 (23%), Positives = 155/387 (40%), Gaps = 50/387 (12%)
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP---FEISPLT 1099
P F + + +V E V+ V A+D D G N + Y + PS + F I +T
Sbjct: 18 PQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQIT 77
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
GV++ LDRE D++ V A D G DVNDN P F +
Sbjct: 78 GVITTKRGLDREFLDRHFFRVKAEDGG-EPSLEGYMDLTINVLDVNDNGPIFER--NIYA 134
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNG--LILY 1216
PE + + V+ + A N + + +++ F IG +G ++
Sbjct: 135 ADIPEDKSIG----DFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK 190
Query: 1217 SLPQRK--------NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
L + K Q+ G P S+T + +T+ DV D P F + Y I E
Sbjct: 191 KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVND-----CTPQFSKKVYSATIRE 245
Query: 1269 N--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
+ VN V V + N ++ + I++ ND + F I+ NG + + + D E+
Sbjct: 246 DVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNF---FSINRINGEVRVKQKLDYEMI 302
Query: 1327 DTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRP 1386
+ ++V A+ + + L T D+ ++ DVNDN+P+F + +
Sbjct: 303 GVFNLLVTAQDK-------------GQPFLYNQTTVDIALI----DVNDNAPQFVSSH-- 343
Query: 1387 LVTAIPTTAPFGYQVMQLKGAIGHHPT 1413
T IP G + +++ H T
Sbjct: 344 FQTMIPENYAVGQEFYRVQAYDKDHGT 370
Score = 67.3 bits (157), Expect = 3e-09
Identities = 76/314 (24%), Positives = 129/314 (41%), Gaps = 26/314 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+T+ + D+NDN P F YH ++ E + G + + I P + P V +
Sbjct: 428 ITITLLDINDNPPKFSQEEYHTSIAENSRWGTS--VLQVKAIDPD-SGPTNVVYSIV--- 481
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGH---FALESSH----KPVLLLRKVLDYDAGDK 195
DR P + S + H F++ +S L+ V D +
Sbjct: 482 SSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDGMLSSTALVYVNVTDSNTHAP 541
Query: 196 EFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
EF+ ++ + + + A D+D G A + Y + + FS+D G +
Sbjct: 542 EFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE--FSVDETTGVIK 599
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
LD + + +T+ +V A+ P A++ V I + D+NDN P F Y
Sbjct: 600 TAGSLDRE-----KVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAK 654
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDR 371
+ E++ G V++V A+D D G+N + Y D +G F+ID G +R LDR
Sbjct: 655 VREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQG--IIRTLKPLDR 712
Query: 372 EAHSSLRMKVYAKE 385
E + V A +
Sbjct: 713 ETIPEYELTVVATD 726
Score = 58.8 bits (136), Expect = 1e-06
Identities = 74/319 (23%), Positives = 137/319 (42%), Gaps = 22/319 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTV-DELTPTGEKAFIFLI-APIGPSLTI 130
G+ Q+ A V ++I DVNDN P+FL Y V +++ P G + A IG + I
Sbjct: 622 GIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQI 681
Query: 131 PLTVP-----RGLTIFKDIRAFDRD-KPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLL 183
+ +G + R KP + Y + V D G ++S K ++
Sbjct: 682 IYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVI 741
Query: 184 LRKVLDYDA-GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
L V D +K V + ++ + A QDL + Y ++ GN +
Sbjct: 742 LEDVKDSPPLFEKPLYEVTVPEDTPPRSPVI---TVKAKSQDLSPETGMMYSIVRGNSPQ 798
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+F ++ G++ +LD + + + + L V+A+ +P T + V + L D+NDN
Sbjct: 799 VFDINPNTGAIQTLMKLDYETQ-----SEYRLTVRATL--SPFFT-ETTVMVYLKDINDN 850
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P E NI++ E + ++ A D D + F + K +++ SG L+
Sbjct: 851 TPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGELS 910
Query: 363 VRNQTVLDREAHSSLRMKV 381
V N+ ++ +++++ V
Sbjct: 911 V-NKKLIQASKPANIKIAV 928
Score = 52.0 bits (119), Expect = 1e-04
Identities = 58/240 (24%), Positives = 98/240 (40%), Gaps = 19/240 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
SFV + + D NDN+PVF+ + YE ++ + + G + +V A D D+G+N ++Y
Sbjct: 630 SFVYIHIA--DVNDNDPVFLKPS-YEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSF- 685
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
SN F I+ G + + E + L V A+DQ P + + V+ +
Sbjct: 686 -ASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILED 744
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEE 616
V K P F YE V + + V ++ D + + Y ++ G
Sbjct: 745 V-------KDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSP 797
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
V F + +G I + L + Y A + T V++ D+ND VL
Sbjct: 798 QV-FDINPNTGAIQTLMKLDYETQSEYRLTVRATL--SPFFTETTVMVYLKDINDNTPVL 854
Score = 46.4 bits (105), Expect = 0.006
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F IN G + L E SE+RL + A + +V V++KD+ND+ PV +
Sbjct: 800 FDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFFTET-TVMVYLKDINDNTPVLEAFH 858
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
N NV+E + K+ A D D LT+ + + ++ +G LSVN +L
Sbjct: 859 MNINVQEGKVPPEARYKIPAYDPDVSD--KLTFKVMEGNAKEWVTLNATSGELSVNKKL 915
>UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 20 SCAF14744, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 2289
Score = 141 bits (341), Expect = 2e-31
Identities = 134/471 (28%), Positives = 212/471 (45%), Gaps = 42/471 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S+V+V V + D NDN PVF P + ++ N GT + K+ A D D G N ++ Y +Q
Sbjct: 734 SYVSVTVHVTDVNDNPPVFEPDEYFPV-VQENVPSGTTVVKMNAKDGDSGANAVMAYVIQ 792
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
+ + F I+PNTGT++ E + + L V+A + P E R SLA V I+
Sbjct: 793 SSD----SDLFVIDPNTGTITTQGFLDYEAKQVYHLTVKAFNV---PDEERCSLANVNIQ 845
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEG 617
+ KG +P F+ Y F V GT VG++ +D + N V Y L+ G
Sbjct: 846 L----KGANEYVPRFVSKQYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRK 901
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F + E +G I V L R + +A N + A + V VN + +
Sbjct: 902 KGFGINETTGQIYVTGALDREKEEKISLKVLA----KNAGSIRGADIDEVFVN----ITV 953
Query: 678 KGAHSPIIF----HVKENSAGAAIGQI--FHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
A+ P +F + + S G + G + F + S + IA + D
Sbjct: 954 LDANDPPVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFSYSIAPESDQKVFTI 1013
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G + PLDRE+ VY +TV+A + G G V + +ED NDN P +
Sbjct: 1014 NTKTGQVSVAAPLDRERTPVYNLTVLA-VDTGTPPATGSATVIVNLEDINDNGPTLTTSY 1072
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLF--GEGKEMFDVDENTGVVKF 848
E +MEN + GT + + A+DAD N F+++L G F + ++ +
Sbjct: 1073 AE--VMENQRAGTAV---TTLTASDADLPPNRGPFLFSLLSSGSANSYFSLSQSGALT-- 1125
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+DRE+ + LS+V +D G +SS + + + D+NDN E +E
Sbjct: 1126 TSREIDREQISDFYLSVVIKDAGVPQMSSTGTIHVKVNDQNDNPSEPRAVE 1176
Score = 134 bits (325), Expect = 1e-29
Identities = 132/473 (27%), Positives = 220/473 (46%), Gaps = 41/473 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD-PDLGQNGMV 495
+ LMS V V ++D+NDN P F N + KS KVGT + +V A D D G N V
Sbjct: 519 QPLMSETTVIVNIVDSNDNPPQFESPNYFTPVAKS-VKVGTRLTRVVAHDKKDFGLNSEV 577
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFV--EASDQPANPSERRYSLA 553
Y + ++ +S F+++ ++G ++VA S I + V A+D+ P SL
Sbjct: 578 EYVITGGNS---SSKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLR 634
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
+ E T P+F + + ++ +GT++ + D + + ++Y++
Sbjct: 635 IAVTEENHHT-------PEFSQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNIT 687
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDV 669
G + G+ F++ RSGV+++ L + ++ A+ A S V + TVHV DV
Sbjct: 688 SGNDRGL-FSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTSYV-SVTVHVTDV 745
Query: 670 NDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND V + P+ V+EN +G + M++ G+ N Q +D
Sbjct: 746 NDNPPVFEPDEYFPV---VQENVPSGTTV-----VKMNAKDGDSGANAVMAYVIQSSDSD 797
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I GTI TQ LD E + VY +TV A FN + V I ++ N+ P F
Sbjct: 798 LFVIDPNTGTITTQGFLDYEAKQVYHLTVKA-FNVPDEERCSLANVNIQLKGANEYVPRF 856
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVV 846
Y + E + GT + + A+D D+G N + Y +FG+ K+ F ++E TG +
Sbjct: 857 VSKQYYFEVSEAAPKGTVV---GEVFASDRDQGDNGVVYYLIFGKSRKKGFGINETTGQI 913
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLS----SEAELIIMIGDENDNKPEFNQ 895
++ +LDREK+ L ++A++ G + E + I + D ND P F Q
Sbjct: 914 -YVTGALDREKEEKISLKVLAKNAGSIRGADIDEVFVNITVLDAND-PPVFTQ 964
Score = 115 bits (276), Expect = 1e-23
Identities = 120/458 (26%), Positives = 196/458 (42%), Gaps = 38/458 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + +LD NDN P F S ++ ++ NA VG + +V D D G N + Q
Sbjct: 430 VKVLINILDVNDNAPRF--SKIFSATVAENAPVGYTVTRVTTTDEDAGSNAN---ECQHW 484
Query: 503 SNLTITSPFKI-NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
++ P K N G++++ RH+ V ASD+ P ++ T+ V
Sbjct: 485 GDIC-KQPLKFQNSTAGSLNI-------NRHSFIVTASDRAVQPL-----MSETTVIVNI 531
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE---QNDVSYDLLHGYEEGV 618
+ P P F Y V +V +GT + ++ +D + ++V Y ++ G
Sbjct: 532 VDSNDNP--PQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEY-VITGGNSSS 588
Query: 619 PFAVEERSGVITVVDDL-SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F +++ SG ITV L S N+ + N LS +T+ + V + N
Sbjct: 589 KFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEFS 648
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ S I + + G AI + + + G + + I + D + G
Sbjct: 649 QSQVSATI--PESLAVGTAIRTLSARDKDK---DMNGVITYNITSGNDRGLFSINSRSGV 703
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ PLD E++ + + V A + G I+ VT+++ D NDNPPVFE Y +
Sbjct: 704 LSLAGPLDFEEKQQHNLRVSA-IDGGWIAKTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQ 762
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN GT + N A D D G NA+ Y + ++F +D NTG + G LD E
Sbjct: 763 ENVPSGTTVVKMN---AKDGDSGANAVMAYVIQSSDSDLFVIDPNTGTITTQG-FLDYEA 818
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
K +Y L++ A + S A + I + N+ P F
Sbjct: 819 KQVYHLTVKAFNVPDEERCSLANVNIQLKGANEYVPRF 856
Score = 100 bits (240), Expect = 3e-19
Identities = 125/464 (26%), Positives = 197/464 (42%), Gaps = 47/464 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN PVF S + ++ +A GT + V + D D+G NG++ Y L
Sbjct: 21 VTVFVSDVNDNAPVFSTSTFHT-TITEDAPTGTDVLLVNSSDADVGNNGVISYSLSGGHG 79
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD--QPANPSERRYSLAVVTIEVT 560
F INP TG + + E R + L V A+D QP S T+ VT
Sbjct: 80 -----QFSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSS------ATVSVT 128
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGV 618
+ P P F PY + ++ G+ V + V D A + Y L+ E
Sbjct: 129 VADINDNP--PRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSLIGRSSE-- 184
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F ++ G IT + L+ + N + T TV V
Sbjct: 185 KFKIDPIRGAITANEKLTGSSEVTLTVRVKDGGANPKTDMTT-VTVRFVT---------- 233
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT--GNVRFLIANQQDVTDDIAIAE-D 735
G P+I +KE + Q + ++++ G+ G + + IA+ ++ I +
Sbjct: 234 GGSFPVI-KLKERAFTFPESQPANHIVTTVTGSSMRGGPLSYYIASG-NLDHAFHIDQLS 291
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + PLD E Y + + A ++G + +V I I+D NDN PVFE ++
Sbjct: 292 GELSIRHPLDYEHIQKYVLWIEAR-DQGFPPYSSYEKVEITIQDVNDNYPVFEKDPFQAD 350
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLD 854
I+EN + ++ A D D G N Y++ KE F ++ TG ++ LD
Sbjct: 351 ILENLSPQRVL----VVSAVDLDSGPNGQLEYSIVDGNKENSFSINRATGEIR-TTRPLD 405
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
REK Y L + A D G + +++I I D NDN P F++I
Sbjct: 406 REKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSKI 449
Score = 100 bits (240), Expect = 3e-19
Identities = 129/482 (26%), Positives = 200/482 (41%), Gaps = 66/482 (13%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I V +N + Q IPE++ +GT I L+A D D +NG I Y S
Sbjct: 635 IAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSG----- 689
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNL--NDNISVRVF 1034
+ F IN R G + +A L E + L +SA+DGG + +SV V
Sbjct: 690 --------NDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTSYVSVTVH 741
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V DVND+ PVF+ Y V+E + + K++A D D G NA + Y IQ SD+DL F
Sbjct: 742 VTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSSDSDL-FV 800
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
I P TG ++ G LD E + Y LTV A N N+ P+F +
Sbjct: 801 IDPNTGTITTQGFLDYEAKQVYHLTVKA-FNVPDEERCSLANVNIQLKGANEYVPRFVSK 859
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGN 1211
E+S + ++ V+ A+ + G +F I
Sbjct: 860 QYYF--------EVSEAAPKGTVVGEVF-ASDRDQGDNGVVYYLIFGKSRKKGFGINETT 910
Query: 1212 GLI-LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-------EMSDKPVFISRYYE 1263
G I + R+ ++ + L L+ A + AD+ DEV + +D PVF Y+
Sbjct: 911 GQIYVTGALDREKEEKISLKVLAKNA-GSIRGADI-DEVFVNITVLDANDPPVFTQELYD 968
Query: 1264 LEIEENVNAPVELVSLNLTEHYENF----KMRYYILNENDTDIRRTFVIDPRNGTLYLVR 1319
+++ E + +P LV+ E ++ + Y I E+D ++ F I+ + G + +
Sbjct: 969 VQVSEGL-SPGGLVTFVSAEDSDSVPSWSRFSYSIAPESD---QKVFTINTKTGQVSVAA 1024
Query: 1320 SPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
DRE Y + V +A D V+V ++D+NDN P
Sbjct: 1025 PLDRERTPVYNLTV-----------------LAVDTGTPPATGSATVIVNLEDINDNGPT 1067
Query: 1380 FT 1381
T
Sbjct: 1068 LT 1069
Score = 95.1 bits (226), Expect = 1e-17
Identities = 55/145 (37%), Positives = 85/145 (58%), Gaps = 9/145 (6%)
Query: 754 MTVIAEFNK-GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
MT I++ N+ GV S +G VT+++ D NDN PVF +T+ I E++ GT++ ++
Sbjct: 1 MTEISDLNQVGVPSLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVL---LV 57
Query: 813 KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG- 871
++DAD G N + Y+L G G F ++ TG + LDRE++ Y+L +VA D G
Sbjct: 58 NSSDADVGNNGVISYSLSG-GHGQFSINPATGQI-ITSSVLDREERANYQLLVVATDGGQ 115
Query: 872 --GLSSEAELIIMIGDENDNKPEFN 894
GLSS A + + + D NDN P F+
Sbjct: 116 PQGLSSSATVSVTVADINDNPPRFH 140
Score = 87.8 bits (208), Expect = 2e-15
Identities = 58/167 (34%), Positives = 83/167 (49%), Gaps = 8/167 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D + + Y + SGNDR LFS++S +G L L LD E Q N V +
Sbjct: 669 LSARDKDKDMNGVITYNITSGNDRGLFSINSRSGVLSLAGPLDF--EEKQQHNLRVSAID 726
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ KT+ V + + D+NDN P FE D Y + EN+P+G +V+++ A D D G
Sbjct: 727 GGWI---AKTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGA 783
Query: 338 NGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N Y + F IDP +G T+ Q LD EA + V A
Sbjct: 784 NAVMAYVIQSSDSDLFVIDPNTG--TITTQGFLDYEAKQVYHLTVKA 828
Score = 87.4 bits (207), Expect = 3e-15
Identities = 91/355 (25%), Positives = 155/355 (43%), Gaps = 24/355 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
DE+ S NV + L AN+ P FV S Y F + A GTV+G+V A D D G NG+V
Sbjct: 833 DEERCSLANVNIQLKGANEYVPRFV-SKQYYFEVSEAAPKGTVVGEVFASDRDQGDNGVV 891
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y + S F IN TG + V + E + ++ + A S R + V
Sbjct: 892 YYLIFGKSR---KKGFGINETTGQIYVTGALDREKEEKISLKVLAKNAG-SIRGADIDEV 947
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF---EQNDVSYDLLH 612
+ +T N P P F Y+ V + G V + D+ + SY +
Sbjct: 948 FVNIT-VLDANDP--PVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFSYSIAP 1004
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVN 670
++ V F + ++G ++V L R P+Y+ +A+ + +AT V++ D+N
Sbjct: 1005 ESDQKV-FTINTKTGQVSVAAPLDRERTPVYNLTVLAV-DTGTPPATGSATVIVNLEDIN 1062
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D G L +++ + ++ AG A+ + T + G F + +
Sbjct: 1063 D-NGPTLTTSYAEV---MENQRAGTAVTTL--TASDADLPPNRGPFLFSLLSSGSANSYF 1116
Query: 731 AIAEDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
++++ G + T + +DRE+ D Y VI + +S G + + + D+NDNP
Sbjct: 1117 SLSQSGALTTSREIDREQISDFYLSVVIKDAGVPQMSSTG--TIHVKVNDQNDNP 1169
Score = 80.6 bits (190), Expect = 3e-13
Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G L Y + SGN F +D ++G L + LD EH +VL ++A P +
Sbjct: 269 GGPLSYYIASGNLDHAFHIDQLSGELSIRHPLDY--EH---IQKYVLWIEARDQGFPPYS 323
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+ +VEI + D+NDN P FE D + I+ENL + VL V A D D G NG+ Y + D
Sbjct: 324 SYEKVEITIQDVNDNYPVFEKDPFQADILENL-SPQRVLVVSAVDLDSGPNGQLEYSIVD 382
Query: 348 --PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ +FSI+ +G +R LDRE + +KV A +
Sbjct: 383 GNKENSFSINRATG--EIRTTRPLDREKVAQYSLKVKATD 420
Score = 77.4 bits (182), Expect = 3e-12
Identities = 43/129 (33%), Positives = 63/129 (48%), Gaps = 2/129 (1%)
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+L+ V VFV DVND+ PVF + ++ + E T + V+++DAD G N ++Y
Sbjct: 14 SLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVISYS 73
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
+ F I+P TG + + LDRE Y L VVA D G D
Sbjct: 74 LSGGHGQ--FSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSATVSVTVAD 131
Query: 1144 VNDNSPKFY 1152
+NDN P+F+
Sbjct: 132 INDNPPRFH 140
Score = 77.0 bits (181), Expect = 4e-12
Identities = 113/459 (24%), Positives = 177/459 (38%), Gaps = 40/459 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V VT+ D NDN P F + Y + ++ G+++ V D D G N + Y
Sbjct: 119 LSSSATVSVTVADINDNPPRF-HHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYS 177
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L S + FKI+P G ++ E L V D ANP + + VT+
Sbjct: 178 LIGRS----SEKFKIDPIRGAITANEKLTGSSEVTLTVRVKDGGANP---KTDMTTVTVR 230
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVG-IGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
G G+ P I + F I T+V + +SY + G +
Sbjct: 231 FVTG--GSFPVI-KLKERAFTFPESQPANHIVTTV----TGSSMRGGPLSYYIASGNLDH 283
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVL 676
F +++ SG +++ L + Y A + S + + DVND V
Sbjct: 284 A-FHIDQLSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVF 342
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K P + EN + + + ++ S G + + I + G
Sbjct: 343 EK---DPFQADILENLSPQRVLVVSAVDLDS---GPNGQLEYSIVDGNKENSFSINRATG 396
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T +PLDREK Y + V A + G+ +V I I D NDN P F + +
Sbjct: 397 EIRTTRPLDREKVAQYSLKVKAT-DWGLPQKNMAVKVLINILDVNDNAPRFS-KIFSATV 454
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN+ +G + + TD D G+NA E + D+ + +KF +
Sbjct: 455 AENAPVGYTVTR---VTTTDEDAGSNA-------NECQHWGDICKQP--LKFQNSTAGSL 502
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ + A D L SE +I+ I D NDN P+F
Sbjct: 503 NINRHSFIVTASDRAVQPLMSETTVIVNIVDSNDNPPQF 541
Score = 74.9 bits (176), Expect = 2e-11
Identities = 71/249 (28%), Positives = 110/249 (44%), Gaps = 23/249 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I++K N++ F + E P GT + ++ A D D G NG + Y +
Sbjct: 844 IQLKGANEYVPRFVSKQYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYY-----LIFGK 898
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL--DGGNLN----DNISVR 1032
S+ K+ F INE G + V +L E E ++++ L + G++ D + V
Sbjct: 899 SR--------KKGFGINETTGQIYVTGALDREKEEKISLKVLAKNAGSIRGADIDEVFVN 950
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDL 1091
+ V D ND PVF + Y+ V E ++ V A D+D + + +Y I P
Sbjct: 951 ITVLDANDP-PVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFSYSIAPESDQK 1009
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
F I+ TG +SV LDRE Y LTV+A D G D+NDN P
Sbjct: 1010 VFTINTKTGQVSVAAPLDRERTPVYNLTVLAVDTG-TPPATGSATVIVNLEDINDNGPTL 1068
Query: 1152 -YAFDELLE 1159
++ E++E
Sbjct: 1069 TTSYAEVME 1077
Score = 74.1 bits (174), Expect = 3e-11
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D G L Y ++ GN FS++ G + + LD + + + L+V+
Sbjct: 363 VSAVDLDSGPNGQLEYSIVDGNKENSFSINRATGEIRTTRPLDRE-----KVAQYSLKVK 417
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P K +V I +LD+NDN P F ++ ++ EN P G++V +V TD+D G
Sbjct: 418 ATDWGLPQKNMAVKVLINILDVNDNAPRFS-KIFSATVAENAPVGYTVTRVTTTDEDAGS 476
Query: 338 N 338
N
Sbjct: 477 N 477
Score = 73.7 bits (173), Expect = 3e-11
Identities = 72/311 (23%), Positives = 125/311 (40%), Gaps = 14/311 (4%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
GL Q + + V + I DVNDN P F + TV E P G
Sbjct: 422 GLPQKNMAVKVLINILDVNDNAPRFSKI-FSATVAENAPVGYTVTRVTTTDEDAGSNANE 480
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
G I K F + N + H IV+ +D A++ ++ ++D +
Sbjct: 481 CQHWG-DICKQPLKFQNSTAGSLNINRHSFIVTASDR---AVQPLMSETTVIVNIVDSND 536
Query: 193 GDKEFQL--VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+F+ K + + +D G+ + + Y + GN F LD +
Sbjct: 537 NPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYVITGGNSSSKFQLDKSS 596
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + + L D F++ + A+ NP + + I + + N + PEF
Sbjct: 597 GWITVASSLISDVN-----KIFMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQ 651
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
+ +I E+L G ++ + A DKD+ NG TY + + +G FSI+ RSG L++
Sbjct: 652 VSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGLFSINSRSGVLSLAGPLD 711
Query: 369 LDREAHSSLRM 379
+ + +LR+
Sbjct: 712 FEEKQQHNLRV 722
Score = 73.3 bits (172), Expect = 5e-11
Identities = 55/181 (30%), Positives = 87/181 (48%), Gaps = 11/181 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D G A + Y +I +D LF +D G++ + LD +A+ + L V+
Sbjct: 774 MNAKDGDSGANAVMAY-VIQSSDSDLFVIDPNTGTITTQGFLDYEAKQ-----VYHLTVK 827
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + + + A V I+L N+ +P F Y + E P G V +V A+D+DQG+
Sbjct: 828 AFNVPDEERCSLANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTVVGEVFASDRDQGD 887
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
NG Y + K F I+ +G + V LDRE + +KV AK S+ G
Sbjct: 888 NGVVYYLIFGKSRKKGFGINETTGQIYVTG--ALDREKEEKISLKVLAKNAG-SIRGADI 944
Query: 396 D 396
D
Sbjct: 945 D 945
Score = 71.7 bits (168), Expect = 1e-10
Identities = 78/282 (27%), Positives = 120/282 (42%), Gaps = 47/282 (16%)
Query: 940 IPENIPIGTTIIKLNALDL-DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ +++ +GT + ++ A D D GLN ++ Y I S+ F +++
Sbjct: 550 VAKSVKVGTRLTRVVAHDKKDFGLNSEVEY------VITGGNSSSK-------FQLDKSS 596
Query: 999 GHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + VA SL + F + I+A D GN L+ S+R+ V + N H P F ++ + +
Sbjct: 597 GWITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQVSATI 656
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E+ + + A D D N +TY I + F I+ +GVLS+ G LD E +
Sbjct: 657 PESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGLFSINSRSGVLSLAGPLDFEEKQ 716
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
++ L V A D G DVNDN P F E DE
Sbjct: 717 QHNLRVSAIDGG-WIAKTSYVSVTVHVTDVNDNPPVF------------EPDE------- 756
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
Y ++EN P GTTV K+ A D D N ++ Y
Sbjct: 757 -------YFPVVQENVPSGTTVVKMNAKDGD--SGANAVMAY 789
Score = 68.9 bits (161), Expect = 1e-09
Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+Q+ P + V + + D+NDN P F ++ +I E+ P G VL V ++D D G N
Sbjct: 8 NQVGVPSLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNN 67
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +Y L G FSI+P +G + +VLDRE ++ ++ V A +
Sbjct: 68 GVISYSLSGGHGQFSINPATG--QIITSSVLDREERANYQLLVVATD 112
Score = 67.3 bits (157), Expect = 3e-09
Identities = 61/212 (28%), Positives = 95/212 (44%), Gaps = 30/212 (14%)
Query: 927 FALDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
F DV+ P+F I E+ P GT ++ +N+ D D G NG I Y +
Sbjct: 24 FVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVISYSLSGG------ 77
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVF 1034
F IN G +I + L E + ++L + A DGG L+ + +V V
Sbjct: 78 ---------HGQFSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSATVSVT 128
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V D+ND+ P F Y ++ + ++ V TD D G NA L Y + ++ F+
Sbjct: 129 VADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSLIGRSSE-KFK 187
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
I P+ G ++ N +L +E LTV +D G
Sbjct: 188 IDPIRGAITANEKLTGSSE--VTLTVRVKDGG 217
Score = 63.7 bits (148), Expect = 4e-08
Identities = 80/327 (24%), Positives = 123/327 (37%), Gaps = 38/327 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IP + G+ + + D D+G N Q+ Y S++ F I+ G
Sbjct: 148 IPASTAAGSLVFAVTVTDEDAGSNAQLHYSLIGR--------SSEK------FKIDPIRG 193
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDV-NDHFPVFKKTWYNFNVEEAQ 1058
+ L SE L + DGG V V+ V FPV K F E+Q
Sbjct: 194 AITANEKLTGSSEVTLTVRVKDGGANPKTDMTTVTVRFVTGGSFPVIKLKERAFTFPESQ 253
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
++ V + G L+Y+I + D F I L+G LS+ LD E KY+L
Sbjct: 254 PANHIVTTVTGSSMRGGP---LSYYIASGNLDHAFHIDQLSGELSIRHPLDYEHIQKYVL 310
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP-EADELSNHNFESVM 1177
+ ARD G DVNDN P F K P +AD L N + + V+
Sbjct: 311 WIEARDQG-FPPYSSYEKVEITIQDVNDNYPVFE--------KDPFQADILENLSPQRVL 361
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL------- 1227
++ N + ++ ++ I G I + P ++ Q +L
Sbjct: 362 VVSAVDLDSGPNGQLEYSIVDGNKENSFSINRATGEIRTTRPLDREKVAQYSLKVKATDW 421
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDK 1254
GLP + +++ + DV D K
Sbjct: 422 GLPQKNMAVKVLINILDVNDNAPRFSK 448
Score = 62.5 bits (145), Expect = 9e-08
Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 10/192 (5%)
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+LS TV V DVND V S FH + N S G
Sbjct: 14 SLSGTCMVTVFVSDVNDNAPVF-----STSTFHTTITEDAPTGTDVLLVNSSDADVGNNG 68
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ + ++ G I T LDRE+R Y++ V+A + V+
Sbjct: 69 VISYSLSGGHGQFS--INPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSATVS 126
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDNPP F H Y I ++ G+ + + TD D G+NA Y+L G
Sbjct: 127 VTVADINDNPPRFHHHPYVTHIPASTAAGSLVFA---VTVTDEDAGSNAQLHYSLIGRSS 183
Query: 835 EMFDVDENTGVV 846
E F +D G +
Sbjct: 184 EKFKIDPIRGAI 195
Score = 60.9 bits (141), Expect = 3e-07
Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 9/165 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+++ D D+G + Y L G+ + FS++ G + LD + N Q L V
Sbjct: 57 VNSSDADVGNNGVISYSLSGGHGQ--FSINPATGQIITSSVLDREERANYQ-----LLVV 109
Query: 278 ASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P ++ A V + + D+NDN P F Y I + G V V TD+D G
Sbjct: 110 ATDGGQPQGLSSSATVSVTVADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAG 169
Query: 337 ENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
N + Y L F IDP G +T + E ++R+K
Sbjct: 170 SNAQLHYSLIGRSSEKFKIDPIRGAITANEKLTGSSEVTLTVRVK 214
Score = 60.1 bits (139), Expect = 5e-07
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG- 831
V + I D NDNPP FE Y + ++ K+GT ++ ++ D G N+ Y + G
Sbjct: 527 VIVNIVDSNDNPPQFESPNYFTPVAKSVKVGT--RLTRVVAHDKKDFGLNSEVEYVITGG 584
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN 889
F +D+++G + + SL + ++ + + A D G LS L I + +EN +
Sbjct: 585 NSSSKFQLDKSSGWIT-VASSLISDVNKIFMVGITATDRGNPPLSGLTSLRIAVTEENHH 643
Query: 890 KPEFNQIEENSKV 902
PEF+Q + ++ +
Sbjct: 644 TPEFSQSQVSATI 656
Score = 54.0 bits (124), Expect = 3e-05
Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 18/134 (13%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
++ ++A+DLDSG NGQ+ Y + +K ++ F IN G + R L
Sbjct: 360 VLVVSAVDLDSGPNGQLEYSI-----VDGNKENS--------FSINRATGEIRTTRPLDR 406
Query: 1010 E--SEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E +++ L + A D G N++V+V + DVND+ P F K ++ V E +
Sbjct: 407 EKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSKI-FSATVAENAPVGYTVT 465
Query: 1066 KVDATDADFGQNAN 1079
+V TD D G NAN
Sbjct: 466 RVTTTDEDAGSNAN 479
Score = 54.0 bits (124), Expect = 3e-05
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y + + +K F ++ G +++ LD + E + VL
Sbjct: 878 VFASDRDQGDNGVVYYLIFGKSRKKGFGINETTGQIYVTGALDREKEEKISLK--VLAKN 935
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + V I +LD ND P F + Y++ + E L G V V A D D
Sbjct: 936 AGSIRGA-DIDEVFVNITVLDANDP-PVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVP 993
Query: 338 N-GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
+ F+Y + + + F+I+ ++G ++V LDRE + V A +T P G+
Sbjct: 994 SWSRFSYSIAPESDQKVFTINTKTGQVSV--AAPLDRERTPVYNLTVLAVDTGTPPATGS 1051
Score = 50.4 bits (115), Expect = 4e-04
Identities = 70/305 (22%), Positives = 120/305 (39%), Gaps = 29/305 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTI 130
G+ +S VTV++ DVNDN P+F + +H T+ E PTG + A +G + I
Sbjct: 11 GVPSLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVI 70
Query: 131 PLTVPRGLTIF-------KDIRAFDRDKPNTPNSDVHYSIVSGNDDGH-FALESSHKPVL 182
++ G F + I + D+ N + +V D G L SS +
Sbjct: 71 SYSLSGGHGQFSINPATGQIITSSVLDREERAN---YQLLVVATDGGQPQGLSSSATVSV 127
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
+ + D V ++F + D+D G A L Y LI G +
Sbjct: 128 TVADINDNPPRFHHHPYVTHIPASTAAGSLVF--AVTVTDEDAGSNAQLHYSLI-GRSSE 184
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F +D + G++ ++L +E T ++V+ N KT V + + +
Sbjct: 185 KFKIDPIRGAITANEKLTGSSE-----VTLTVRVKDGGANP--KTDMTTVTVRFV-TGGS 236
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P ++ + E+ P V V + G +Y + + AF ID SG
Sbjct: 237 FPVIKLKERAFTFPESQPANHIVTTVTGSSM---RGGPLSYYIASGNLDHAFHIDQLSGE 293
Query: 361 LTVRN 365
L++R+
Sbjct: 294 LSIRH 298
Score = 41.9 bits (94), Expect = 0.13
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 25 RDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL-VRIGA---GLNQISAY 80
+D+N I + + L +S V+ DF+E +R+ A G ++Y
Sbjct: 676 KDMNGVITYNITSGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTSY 735
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+SVTV++ DVNDN P+F Y V E P+G
Sbjct: 736 VSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSG 768
Score = 41.5 bits (93), Expect = 0.17
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Query: 130 IPLTVPRGLTIFKDIRAFD-RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+ T+P L + IR RDK N + Y+I SGND G F++ +S VL L L
Sbjct: 652 VSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGLFSI-NSRSGVLSLAGPL 710
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAID 222
D++ + V G I K +H D
Sbjct: 711 DFEEKQQHNLRVSAIDGGWIAKTSYVSVTVHVTD 744
>UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Fat4 - Strongylocentrotus purpuratus
Length = 4601
Score = 140 bits (340), Expect = 2e-31
Identities = 187/697 (26%), Positives = 305/697 (43%), Gaps = 73/697 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +++ ND+ P+F Y ++ N G++ V+A D D G G V Y + +
Sbjct: 2380 VGINVININDHTPIF-EGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGNT 2438
Query: 505 LTITSPFKINPNTG-TVSVAESPILE-GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
I F+I+ TG T V +LE G + L VEA D P + R S +TI VT
Sbjct: 2439 DNI---FRIDQTTGQTGEVFVQGLLETGTYRLVVEARDTPGDIPSSRASSTTLTIVVT-- 2493
Query: 563 TKGNKPDI-PDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE--EGV 618
+ D+ P F G+ + V N +G + I A +D + L++ +
Sbjct: 2494 ---DIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAIN-SDATGQLVYTITGPDSQ 2549
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
F + + S I V L R + Y+F V + ++ L+ + ++V+DVND
Sbjct: 2550 TFMINQLSAGIQVNGPLDRETKDFYEF-GVIVTDSMGLTAMGTVHINVLDVNDFAPAFND 2608
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
++ F + ENS G ++ S Y NV F I + DI GTI
Sbjct: 2609 SVYN---FTIPENSPGG-----YYVGGVSAYDLDGDNVNFFIQTGGEDKFDIG-GTSGTI 2659
Query: 739 FTQKP---LDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
T P LDRE++ Y +TV +++ +SG V IY+ D ND+PP F+ + +
Sbjct: 2660 -TVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTAT--VYIYLIDINDSPPKFDASFLDQ 2716
Query: 795 FI-MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I + G I + ATD D +N + E DVD + SL
Sbjct: 2717 IISIPEDTPGNTIV--TTVTATDDDLNSNINYQIVSVSVYDED-DVDITSFFDYRTVFSL 2773
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+ + S V R+ ++ + I D N P F +EN++V I +
Sbjct: 2774 NPTNGNITLTSPVDRE---VTEKFVFSISARDLNSQNPIFGTSQENAQVTILITDINDNH 2830
Query: 914 AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII-KLNALDLDSGLNGQIRYEFNS 972
F P F L +PE+ G+ I L ALD D GLNG++ Y +
Sbjct: 2831 PAFQ----PPGTTFILRQ--------LPESFGAGSPIPGNLLALDPDLGLNGEVMYIIQN 2878
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDN 1028
+P + I++ G + + ++ E + L + A+D G +LN +
Sbjct: 2879 PSGVPVT--------------IDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTS 2924
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I V + + D ND+ PVF + + E++ + V+ATDAD G + +TY + D
Sbjct: 2925 IPVYLEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGGD 2984
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
F I+ +GV+++ ++D+ET+ +++LTV ARDN
Sbjct: 2985 G--KFTINQDSGVITLLQQVDKETQSQHMLTVFARDN 3019
Score = 136 bits (328), Expect = 6e-30
Identities = 187/694 (26%), Positives = 281/694 (40%), Gaps = 86/694 (12%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + +LD ND P+F N Y + N+ GT + +V A D DL G V Y L
Sbjct: 1567 VPVIINILDINDVTPLFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLIGN 1626
Query: 503 SNLTITSPFKINPNTGTVSVAESPI--LEGRH--ALFVEASDQPANPSERRYSLAVVTIE 558
N IN +TG +SV PI L G + V A+DQ A+P R +A VT+
Sbjct: 1627 PNF-----LTINSDTGVISV-NGPIADLSGSRNFTMTVRATDQ-ASPFLR--GVATVTVT 1677
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V T IP F + Y V NV T V ++ ++Y + V
Sbjct: 1678 VVDDTV----TIPIFTLSRYPATVIENVNADTPVTRVSATLNGNPAGITYAIDPNASPAV 1733
Query: 619 P--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F ++E +G IT + R Y F A E++ T+ V+++D ND
Sbjct: 1734 LEIFKIDENTGHITTEGAIDREVEDFYAFTVFAYHEDSVAPGSTSVWVNILDENDNPPEF 1793
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ SP+ V+EN+ G +F N A G
Sbjct: 1794 ITVPPSPV--SVRENTGGNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGG 1851
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
TI PLDRE++D Y++TV A + G S + + + I + D NDN P++ YEG I
Sbjct: 1852 TIVVTSPLDRERQDFYQLTVTAT-DGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSI 1910
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDR 855
EN+ I + D D ++ F Y++ G+ MF+++ N + + LDR
Sbjct: 1911 NENNFTSNPIIT---VMVNDLDLPSSNNFEYSIIAGDPMGMFEINSNGEIT--VSSLLDR 1965
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
E++ Y+L++ D + I D EN I ET
Sbjct: 1966 EQQETYQLTIELIDQTNSPPARTTTLAIITVGD---------ENDNTPIFAET------- 2009
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
+I V DV + GP +NIP+ L A D+D GLN I Y S+
Sbjct: 2010 --VIRV--------DVTE-GPS---SQNIPV----YMLTANDIDLGLNRDIIYAIGSQ-- 2049
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNI---S 1030
+ + +F IN G + +L E SE+ L ++A D +
Sbjct: 2050 -----------QPQSHFQINPETGMISTTTALDWETISEYTLIVTATDQSPTEPRTGTAT 2098
Query: 1031 VRVFVKDVNDHFPVFKKTWYN-FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
V V V D+ND P+F + Y ++V E + + + ATD D G +TY + S
Sbjct: 2099 VIVSVNDINDGAPMFVRDVYGPYSVVE-EVSNSYIDSFQATDTDQGLAGTVTYSVIVSVN 2157
Query: 1090 DL----PFEISPLTGVLSVNGELDRETEDKYILT 1119
D+ P + + G SV E+ D + T
Sbjct: 2158 DINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQAT 2191
Score = 122 bits (294), Expect = 8e-26
Identities = 191/734 (26%), Positives = 300/734 (40%), Gaps = 111/734 (15%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + + D NDN P F N Y ++ +N T++ V A DPD G NG+V+Y++ +
Sbjct: 3347 VSIIVRDVNDNTPTF-EENPYISTVTTN----TLLVDVHANDPDEGGNGIVIYEIVSGNE 3401
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ F+I+ TG +++ +P+ L + L V D NP R S V + +
Sbjct: 3402 ---DNRFQIDNRTGVITLV-NPLDSQLIRNYTLVVIGHDL-GNP--RLQSNTTVDLRINY 3454
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGI--GTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P P F+ P + GS V I +GQ+ +N +DV + + Y
Sbjct: 3455 -LGLNAP--PSFV-RPNQ---GSTVFITENNPLGQLIINAFAVDDDVGANGVVDYSILPN 3507
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F + +G + V L Y+ V ++ N T V V D ND +
Sbjct: 3508 F---DYNGGLIPVKPLDFETFTNYNLTVVVTDDSGNRD-TTYVAVTVTDANDHNPTFVPD 3563
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+S + + G +G + + ++ ++ + I + + + G I
Sbjct: 3564 QYSLTV--TENEPPGTQVGVVITIDGDTL--PEYTDIIYTILTGNGLGNFTINSTTGIIT 3619
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T LDREK Y +T+ AE G +G V+I + D NDN P FE Y + N
Sbjct: 3620 TATILDREKTSEYVLTIGAENPVGGTTGTAT--VSIIVRDVNDNTPTFEENPYTSTVTTN 3677
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ + +D + A D DEG N + +Y + G F +D TGV+ + E +
Sbjct: 3678 TLL-----VD--VHANDPDEGGNGIVIYEIVSGNEDNRFTIDNRTGVITLVNPL---ESQ 3727
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH-RETKLNGTAGFT 917
++ +LV +IG + N Q++ N+ V + LN F
Sbjct: 3728 LIRNYTLV---------------VIGHDLGNP----QLQSNTTVDLRINYLGLNAPPSF- 3767
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
V+P G I EN P+G II A+D D G NG + Y I
Sbjct: 3768 ---VRPNQ---------GSTVFITENNPLGLLIINAFAVDDDVGANGVVDYS------IL 3809
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRV 1033
P+ +D F I+ G + + S E + L + A D G NL+ + + +
Sbjct: 3810 PNFDYSD-------FTIDPVTGDITILVSADREIKDSYTLTVVATDRGDPNLSTSSTFVI 3862
Query: 1034 FVKDVNDHFPVFKKT-------WYNFNVEEAQYTRRVLGKVD-ATDADFGQNANLTYFIQ 1085
V D ND+ P F + N NV E ++G VD A D D G N + Y I
Sbjct: 3863 RVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLDLGANGQIFYHIV 3922
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD----NGX----XXXXXXXXXX 1137
S F I+ TGV++VNG LDRE + + ++A + NG
Sbjct: 3923 DSTVGGIFVINSTTGVVTVNGTLDREDIGVHTIYILATNDATYNGTGPYNVLDNISLKEV 3982
Query: 1138 XXXXXDVNDNSPKF 1151
D+NDN+P+F
Sbjct: 3983 KITLLDINDNAPRF 3996
Score = 116 bits (280), Expect = 4e-24
Identities = 137/514 (26%), Positives = 215/514 (41%), Gaps = 52/514 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V VT+ DAND+NP FVP Y ++ N GT +G V +D D L + ++Y + +
Sbjct: 3242 VAVTVTDANDHNPTFVPDQ-YSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTILTGN 3300
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
L F IN TG ++ A IL+ + NP A V+I + R
Sbjct: 3301 GL---GNFTINSTTGIITTAT--ILDREKTSEYVLTIGAENPVGGTTGTATVSI-IVRDV 3354
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFA 621
N P F PY V +N T + + ND E + V Y+++ G E+ F
Sbjct: 3355 NDNTPT---FEENPYISTVTTN----TLLVDVHANDPDEGGNGIVIYEIVSGNEDN-RFQ 3406
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV----VDVNDERGVLL 677
++ R+GVIT+V+ L Y + + N + +N TV + + +N +
Sbjct: 3407 IDNRTGVITLVNPLDSQLIRNYTLVVIG-HDLGNPRLQSNTTVDLRINYLGLNAPPSFVR 3465
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
S + F + N G I F + + NG V + I D +G
Sbjct: 3466 PNQGSTV-FITENNPLGQLIINAFAVD-DDVGANGV--VDYSILPNFDY--------NGG 3513
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ KPLD E Y +TV+ + G V + + D ND+ P F Y +
Sbjct: 3514 LIPVKPLDFETFTNYNLTVVVTDDSG---NRDTTYVAVTVTDANDHNPTFVPDQYSLTVT 3570
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN GT++ + I E T+ ++ L G G F ++ TG++ LDREK
Sbjct: 3571 ENEPPGTQVGVVITIDGDTLPEYTDIIYTI-LTGNGLGNFTINSTTGIIT-TATILDREK 3628
Query: 858 KIMYKLSLVARD-TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR-------IHRETK 909
Y L++ A + GG + A + I++ D NDN P F + S V +H
Sbjct: 3629 TSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYTSTVTTNTLLVDVHANDP 3688
Query: 910 LNGTAGFTIIEV---KPKNKFALDVDQLGPLFLI 940
G G I E+ N+F +D ++ G + L+
Sbjct: 3689 DEGGNGIVIYEIVSGNEDNRFTID-NRTGVITLV 3721
Score = 111 bits (268), Expect = 1e-22
Identities = 137/573 (23%), Positives = 233/573 (40%), Gaps = 60/573 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + V + ++D NDNNPVF + + ++ + +G + V A D D G +G V Y
Sbjct: 2921 LNTSIPVYLEIIDNNDNNPVFGAQS-HTTTIIESEPIGAFVFNVNATDADSGGSGRVTYS 2979
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
L + F IN ++G +++ + E +H L V A D P + + R V
Sbjct: 2980 L-----IGGDGKFTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVI 3034
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ V + P + P +G G VG I D + +D + L +
Sbjct: 3035 VNVLDAN-----EFPPVVTQPIFTIDEGGIG-GEVVGVIEAYDPDDPDDPNQSLYYVVVS 3088
Query: 617 GVP------FAVEERSGVITVVDDLSRYNR---PMYDFEAVALQE-NANLSIVTNATVHV 666
P F + +G I L R N D + + + N NL T A +++
Sbjct: 3089 SQPEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYI 3148
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG---TGNVRFLIANQ 723
D+ND + F + GQ + + ++ N N+R+ I
Sbjct: 3149 NDLNDNQPT----------FDLPLYDVTVVEGQ-YSDPIITVVANDPDQNSNLRYEILGG 3197
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
++ + DG + KPLD E Y +TV+ + G V + + D ND+
Sbjct: 3198 N--LNNTFVLVDGGLIPVKPLDFETFTNYNLTVVVTDDSG---NRDTTYVAVTVTDANDH 3252
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F Y + EN GT++ I E T+ ++ L G G F ++ T
Sbjct: 3253 NPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTI-LTGNGLGNFTINSTT 3311
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARD-TGGLSSEAELIIMIGDENDNKPEFNQ------I 896
G++ LDREK Y L++ A + GG + A + I++ D NDN P F + +
Sbjct: 3312 GIIT-TATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTV 3370
Query: 897 EENS-KVRIHRETKLNGTAGFTIIEV---KPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
N+ V +H G G I E+ N+F +D ++ G + L+ P+ + +I+
Sbjct: 3371 TTNTLLVDVHANDPDEGGNGIVIYEIVSGNEDNRFQID-NRTGVITLVN---PLDSQLIR 3426
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA 985
L + G R + N+ V + + L +A
Sbjct: 3427 NYTLVVIGHDLGNPRLQSNTTVDLRINYLGLNA 3459
Score = 111 bits (267), Expect = 1e-22
Identities = 173/714 (24%), Positives = 293/714 (41%), Gaps = 74/714 (10%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA-SQ 280
D DL Y +I+G+ +F ++S NG + + LD + Q T+ L ++ Q
Sbjct: 1927 DLDLPSSNNFEYSIIAGDPMGMFEINS-NGEITVSSLLDRE-----QQETYQLTIELIDQ 1980
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENG 339
N+P I + D NDN P F + + E V + A D D G N
Sbjct: 1981 TNSPPARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNR 2040
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS 397
+ Y + P+ F I+P +G ++ T LD E S + V A + +P+ T +
Sbjct: 2041 DIIYAIGSQQPQSHFQINPETGMIS--TTTALDWETISEYTLIVTATDQSPTEPRTGTAT 2098
Query: 398 QRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTEN--IEYY-----DEQLMSFV--NVEVT 448
++ + AP+ P V + N I+ + D+ L V +V V+
Sbjct: 2099 VIVSV---NDINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQATDTDQGLAGTVTYSVIVS 2155
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-LQRTSNLTI 507
+ D ND P+FV +S+ + I +A D D G GMV Y + + S+L
Sbjct: 2156 VNDINDGAPMFVRDVYGPYSVVEEVS-NSYIDSFQATDTDQGLAGMVTYSVIGQYSDL-- 2212
Query: 508 TSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEVTRG- 562
F I P TG +++ L+ + V A+D V+TI R
Sbjct: 2213 ---FFIQPQTGVLTIRPDRALDYETITEFNITVVATDMGVPALSSSPQTGVLTIRPDRAL 2269
Query: 563 -----TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGY 614
T+ N + MG P + S+ +G +V I +ND FE + L
Sbjct: 2270 DYETITEFNITVVATDMGNPA---LSSSTLVGINV--ININDHTPIFEGIPYTITLSKNI 2324
Query: 615 EEG----VPFAVEERSGVITVV----DDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
G V A ++ +G+ V D + N D ++ + T ++V
Sbjct: 2325 SAGSLAYVVRATDDDAGIFGEVRYQITDGNTDNIFRIDQTIDSMGATEEKTGQTLVGINV 2384
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI--ANQQ 724
+++ND + +G P + +N + ++ + G VR+ I N
Sbjct: 2385 ININDHTPI-FEGI--PYTITLSKNISAGSLAYVVRATDDD--AGIFGEVRYQITDGNTD 2439
Query: 725 DV-TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI--SGAGIYQVTIYIEDEN 781
++ D + G +F Q L+ YR+ V A G I S A +TI + D
Sbjct: 2440 NIFRIDQTTGQTGEVFVQGLLE---TGTYRLVVEARDTPGDIPSSRASSTTLTIVVTDIG 2496
Query: 782 DNPPVFEHAT-YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
D P F ++ + G + EN+ +G I M I+A ++D T L +YT+ G + F ++
Sbjct: 2497 DLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINSD-ATGQL-VYTITGPDSQTFMIN 2554
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
+ + ++ + LDRE K Y+ ++ D+ GL++ + I + D ND P FN
Sbjct: 2555 QLSAGIQ-VNGPLDRETKDFYEFGVIVTDSMGLTAMGTVHINVLDVNDFAPAFN 2607
Score = 111 bits (266), Expect = 2e-22
Identities = 141/558 (25%), Positives = 239/558 (42%), Gaps = 44/558 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN P F + YE S+ N +G+ I V+A DPDLG N +VLY + +N
Sbjct: 1464 VSVIVTDVNDNAPTFRDIS-YEESIFENHPLGSNILTVQADDPDLGVNAVVLYRIISGNN 1522
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ F ++ G +++ +P+ ++ ++ L V+A + + + + +++
Sbjct: 1523 NNL---FNVD-GQGNINLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDIND 1578
Query: 562 GTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
T P F Y + N GT V Q+ D + D++ D+ + F
Sbjct: 1579 VT-------PLFQQQNYYRPDLSENSPSGTPVLQVFAQD--QDLDLAGDVQYSLIGNPNF 1629
Query: 621 -AVEERSGVITV---VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
+ +GVI+V + DLS A Q + L V TV VVD +
Sbjct: 1630 LTINSDTGVISVNGPIADLSGSRNFTMTVRATD-QASPFLRGVATVTVTVVDDTVTIPIF 1688
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + ++ +A + ++ +++ GN G + N +I ++
Sbjct: 1689 TLSRYPATV--IENVNADTPVTRV----SATLNGNPAGITYAIDPNASPAVLEIFKIDEN 1742
Query: 737 T--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
T I T+ +DRE D Y TV A V G+ V + I DENDNPP F
Sbjct: 1743 TGHITTEGAIDREVEDFYAFTVFAYHEDSVAPGS--TSVWVNILDENDNPPEFITVPPSP 1800
Query: 795 F-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE--NTGVVKFIGD 851
+ EN+ G + + + +ATD D G NA +++ G G F+V + N G +
Sbjct: 1801 VSVRENT--GGNVPV-GLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGGTIVVTS 1857
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ-IEENSKVRIHRET 908
LDRE++ Y+L++ A D G LSS L I + D NDN P + + + E S + +
Sbjct: 1858 PLDRERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTS 1917
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
T +++ N F + P+ + N T+ L LD + Q+
Sbjct: 1918 NPIITVMVNDLDLPSSNNFEYSIIAGDPMGMFEINSNGEITVSSL--LDREQQETYQLTI 1975
Query: 969 EFNSEVYIPPSKLSADAL 986
E + PP++ + A+
Sbjct: 1976 ELIDQTNSPPARTTTLAI 1993
Score = 109 bits (263), Expect = 4e-22
Identities = 222/974 (22%), Positives = 366/974 (37%), Gaps = 151/974 (15%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN-GMVLYDLQRTS 503
V V +LDAN+ PV F++ G V+G ++A DPD + LY + +S
Sbjct: 3033 VIVNVLDANEFPPVVTQPI---FTIDEGGIGGEVVGVIEAYDPDDPDDPNQSLYYVVVSS 3089
Query: 504 NLTITSP-FKINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ F IN TG + ++ + R L V D NP+ + A++ I
Sbjct: 3090 QPEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDD-GNPNLGTPTTAIIYI 3148
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+ P F Y+ V + + ND + +++ Y++L G
Sbjct: 3149 NDLNDNQ------PTFDLPLYDVTVVEGQ-YSDPIITVVANDPDQNSNLRYEILGGNLNN 3201
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
V+ G + V L Y+ V ++ N T V V D ND +
Sbjct: 3202 TFVLVD---GGLIPVKPLDFETFTNYNLTVVVTDDSGNRD-TTYVAVTVTDANDHNPTFV 3257
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+S + + G +G + + ++ ++ + I + + + G
Sbjct: 3258 PDQYSLTV--TENEPPGTQVGAVITIDGDTL--PEYTDIIYTILTGNGLGNFTINSTTGI 3313
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T LDREK Y +T+ AE G +G V+I + D NDN P FE Y +
Sbjct: 3314 ITTATILDREKTSEYVLTIGAENPVGGTTGTAT--VSIIVRDVNDNTPTFEENPYISTVT 3371
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDRE 856
N+ + +D + A D DEG N + +Y + G F +D TGV+ + + LD +
Sbjct: 3372 TNTLL-----VD--VHANDPDEGGNGIVIYEIVSGNEDNRFQIDNRTGVITLV-NPLDSQ 3423
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH-RETKLNGTAG 915
L+ T +++IG + N +++ N+ V + LN
Sbjct: 3424 --------LIRNYT---------LVVIGHDLGNP----RLQSNTTVDLRINYLGLNAPPS 3462
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
F V+P G I EN P+G II A+D D G NG + Y
Sbjct: 3463 F----VRPNQ---------GSTVFITENNPLGQLIINAFAVDDDVGANGVVDYSI----- 3504
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFV 1035
+P + + VK + + L + D D V V V
Sbjct: 3505 LPNFDYNGGLIPVKPL--------------DFETFTNYNLTVVVTDDSGNRDTTYVAVTV 3550
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFE 1094
D NDH P F Y+ V E + +G V D D + ++ Y I + F
Sbjct: 3551 TDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLGNFT 3610
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
I+ TG+++ LDRE +Y+LT+ A + DVNDN+P F
Sbjct: 3611 INSTTGIITTATILDREKTSEYVLTIGAEN--PVGGTTGTATVSIIVRDVNDNTPTF--- 3665
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGN 1211
E + ++ + +++ V+ +E G + ++ + + D I N
Sbjct: 3666 ---------EENPYTSTVTTNTLLVDVHANDPDEGGN-GIVIYEIVSGNEDNRFTIDNRT 3715
Query: 1212 GLILYSLPQRKN----------QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRY 1261
G+I P +LG P L S + + + + + ++ P F+
Sbjct: 3716 GVITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRI----NYLGLNAPPSFVRPN 3771
Query: 1262 YELEIEENVNAPVELVSLNL----TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYL 1317
+ N P+ L+ +N + N + Y IL D F IDP G + +
Sbjct: 3772 QGSTVFITENNPLGLLIINAFAVDDDVGANGVVDYSILPNFDYS---DFTIDPVTGDITI 3828
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
+ S DRE+KD+Y + V VA D + V+R+ D NDN+
Sbjct: 3829 LVSADREIKDSYTLTV-----------------VATDRGDPNLSTSSTFVIRVLDENDNN 3871
Query: 1378 PKFTNG---NRPLV 1388
P F N P+V
Sbjct: 3872 PAFPRPDGMNNPIV 3885
Score = 107 bits (257), Expect = 2e-21
Identities = 117/457 (25%), Positives = 190/457 (41%), Gaps = 34/457 (7%)
Query: 447 VTLLDANDNNPVFVP---SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
VT+ D NDNNPVF+ N+Y S+ N + GT I +V D D G N V Y +
Sbjct: 936 VTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSI---I 992
Query: 504 NLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ I + F INP +G ++ + P + L V A++ P + T+ +T
Sbjct: 993 SGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATN-PTPGVAPATGTSTSTVIITV 1051
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVP 619
+ P P F + ++ +GT+V +I D E + ++Y + G G
Sbjct: 1052 NDVNDSP--PRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITAG-NTGGH 1108
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
F + SG +T++ L R ++ A + A S T V V+D ND +
Sbjct: 1109 FQINPVSGDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAP---Q 1165
Query: 679 GAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ + + EN + Q+ T+ ++ F I N +V I + G
Sbjct: 1166 WSPQSYVDSILENVPLNTFVLQVVATDADQ---GTNADLSFTINNANNV--PFVIDDQGN 1220
Query: 738 IFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T PL+RE Y V + + +G VTI I D ND PPV + +YE +
Sbjct: 1221 IRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFTV 1280
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E+ T + + ATD D + YT D +G ++ LD
Sbjct: 1281 SEDVNFNTFVGQ---VTATDPD--LSGTLTYTFVPADP---DFSYISGTIR-TNTQLDAN 1331
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
++ +Y++++ A D S A + I + D N+ P F
Sbjct: 1332 QQQVYQMTVFASDGVQNSQSAPVTINVLDVNNQAPSF 1368
Score = 106 bits (255), Expect = 4e-21
Identities = 128/464 (27%), Positives = 196/464 (42%), Gaps = 43/464 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V +LD NDN P + P + Y S+ N + T + +V A D D G N + + + +N
Sbjct: 1152 LKVIVLDFNDNAPQWSPQS-YVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNANN 1210
Query: 505 LTITSPFKINPNT-GTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ + N T G ++ P ++ V D +P + A VTI +
Sbjct: 1211 VPFVIDDQGNIRTSGPLNRETVP----QYNFLVTVLDN-GSPQQAGNPPATVTINIL--D 1263
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE 623
++P + D YEF V +V T VGQ+ D D+S L + + P
Sbjct: 1264 VNDEPPVLD--RNSYEFTVSEDVNFNTFVGQVTATDP----DLSGTLTYTFVPADP-DFS 1316
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
SG I L + +Y A + S T++V+DVN++ G +
Sbjct: 1317 YISGTIRTNTQLDANQQQVYQMTVFA-SDGVQNSQSAPVTINVLDVNNQAPSFGLGTY-- 1373
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF----LIANQQDVTDD--IAIAEDGT 737
+ + E+S + + N + TG + + L Q T D + E
Sbjct: 1374 -VKSLPEDSPFQTL--VVDLNATDPDNGNTGLIIYSFESLSRTQGPFTVDPYTGVVE--- 1427
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISG---AGIYQVTIYIEDENDNPPVFEHATYEG 794
I T LDRE +D Y M VIA SG G V++ + D NDN P F +YE
Sbjct: 1428 ISTTAGLDRETQDEYTMIVIAVDQPA--SGQPMTGTATVSVIVTDVNDNAPTFRDISYEE 1485
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSL 853
I EN +G+ I ++A D D G NA+ +Y + G +F+VD G + L
Sbjct: 1486 SIFENHPLGSNIL---TVQADDPDLGVNAVVLYRIISGNNNNLFNVD-GQGNINLGSTPL 1541
Query: 854 DREKKIMYKLSLVA--RDTGGLSSEAELIIMIGDENDNKPEFNQ 895
DRE + Y L + A D ++E +II I D ND P F Q
Sbjct: 1542 DREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDINDVTPLFQQ 1585
Score = 98.7 bits (235), Expect = 1e-18
Identities = 121/489 (24%), Positives = 214/489 (43%), Gaps = 46/489 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +LD N+ P F Y S+ ++ T++ + A DPD G G+++Y + S
Sbjct: 1354 VTINVLDVNNQAPSF-GLGTYVKSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSR 1412
Query: 505 LTITSPFKINPNTGTVSVAESPIL----EGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
PF ++P TG V ++ + L + + + V A DQPA+ + A V++ VT
Sbjct: 1413 --TQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQPAS-GQPMTGTATVSVIVT 1469
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDLLHGYEEGV 618
+ P F YE + N +G+++ ++ +D N V Y ++ G +
Sbjct: 1470 ----DVNDNAPTFRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRIISGNNNNL 1525
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN---ATVHVVDVNDERGV 675
F V+ + + L R + Y + N++LS+ TN ++++D+ND +
Sbjct: 1526 -FNVDGQGNINLGSTPLDREMQDQYFL--IVQAYNSDLSVGTNEVPVIINILDINDVTPL 1582
Query: 676 L-LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAI 732
+ + P + ENS +G + Q+F + + G+V++ LI N +T +
Sbjct: 1583 FQQQNYYRP---DLSENSPSGTPVLQVFAQDQDL---DLAGDVQYSLIGNPNFLTIN--- 1633
Query: 733 AEDGTIFTQKPL-DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
++ G I P+ D + MTV A G+ VT+ + D+ P+F +
Sbjct: 1634 SDTGVISVNGPIADLSGSRNFTMTVRATDQASPFL-RGVATVTVTVVDDTVTIPIFTLSR 1692
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK----EMFDVDENTGVVK 847
Y ++EN T + + AT G A Y + E+F +DENTG +
Sbjct: 1693 YPATVIENVNADTPVTR---VSAT--LNGNPAGITYAIDPNASPAVLEIFKIDENTGHIT 1747
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
G ++DRE + Y ++ A ++ + + I DENDN PEF + S V +
Sbjct: 1748 TEG-AIDREVEDFYAFTVFAYHEDSVAPGSTSVWVNILDENDNPPEFITVPP-SPVSVRE 1805
Query: 907 ETKLNGTAG 915
T N G
Sbjct: 1806 NTGGNVPVG 1814
Score = 97.5 bits (232), Expect = 2e-18
Identities = 123/482 (25%), Positives = 199/482 (41%), Gaps = 45/482 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S + V++L+ D NPVF+ + Y+ ++ VG+ + + A DPD ++
Sbjct: 708 DTSLSSTATLTVSVLNIQDTNPVFI-NTPYDVTIPETLPVGSTVQTITATDPDSNDGNII 766
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSV-----AESPILEGRHALFVEASDQPANPSERRY 550
Y+L + + F I+ TG ++V ++P+L + L V A S
Sbjct: 767 TYNLVVSDS---QGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSA----VETSSGGV 819
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG-QIRVNDA--FEQNDVS 607
S A V+ VT ++P P F Y + + + + + I VND + V+
Sbjct: 820 SFAQVSFNVTVSPANDEP--PMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVT 877
Query: 608 YDLLHGYEEGVPFAVEERSGV------ITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
L +G VPF V V I + L N Y + A+ + +
Sbjct: 878 VSLQNG--NSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDG--QDIAP 933
Query: 662 ATVHVVDVNDERGVLLKGAHSPII-FHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
V V DVND V + I + EN G I Q+ T+ S G+ +
Sbjct: 934 LMVTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADS--GSNAAVTYSI 991
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGV--ISGAGIYQVTIY 776
I+ + I G I + L Y ++V A GV +G V I
Sbjct: 992 ISGNINNVFTIN-PTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIIT 1050
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGK 834
+ D ND+PP F + FI E +++GT + I ATD D EG ++ T G
Sbjct: 1051 VNDVNDSPPRFSDDEFTVFINEAAQVGTTVTR---ITATDEDIPEGDRLTYIITAGNTGG 1107
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
F ++ +G V + LDRE + + L++ A D G S+ L +++ D NDN P+
Sbjct: 1108 H-FQINPVSGDVTLL-RQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQ 1165
Query: 893 FN 894
++
Sbjct: 1166 WS 1167
Score = 93.1 bits (221), Expect = 5e-17
Identities = 120/481 (24%), Positives = 198/481 (41%), Gaps = 46/481 (9%)
Query: 445 VEVTLLDANDNNPVF--VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ V + D ND P F +P+ Y F NA G+ + +V D D G V Y +
Sbjct: 603 IYVRITDVNDIAPTFTNLPNITYVFE---NATFGSELYQVITTDEDTFYGGFVTYSISLV 659
Query: 503 SNLTITSP----FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS-LAVVTI 557
+ T S F I G + +A S E FV + + S A +T+
Sbjct: 660 TPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDYGTGDTSLSSTATLTV 719
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYE 615
V N P F+ PY+ + + +G++V I D + + N ++Y+L+
Sbjct: 720 SVLNIQDTN----PVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGNIITYNLVVSDS 775
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPM---YDFEAVALQENAN-LSIV-TNATVHVVDVN 670
+G F +++ +G+ITV + R N + Y A++ ++ +S + V V N
Sbjct: 776 QGY-FVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQVSFNVTVSPAN 834
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV-TDD 729
DE + + ++S I + S + + N + + T V N
Sbjct: 835 DEPPMFDQNSYSASI--PESASVNSQLPITITVNDGDLITDSTVTVSLQNGNSVPFRVSP 892
Query: 730 IAIAEDGT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ GT I +PLD E Y + + A G I + + + D NDN PVF
Sbjct: 893 TQVVGSGTVDILITQPLDFENNQQYTLQLQAVDG----DGQDIAPLMVTVTDVNDNNPVF 948
Query: 788 EHAT----YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDEN 842
+ Y G I EN + GT I + TDAD G+NA Y++ G +F ++
Sbjct: 949 INRPIDNIYRGSINENDQTGTFIVQ---VSTTDADSGSNAAVTYSIISGNINNVFTINPT 1005
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARD-TGGLS-----SEAELIIMIGDENDNKPEFNQI 896
+G + L Y LS+ A + T G++ S + +II + D ND+ P F+
Sbjct: 1006 SGAITNT-QILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVNDVNDSPPRFSDD 1064
Query: 897 E 897
E
Sbjct: 1065 E 1065
Score = 87.8 bits (208), Expect = 2e-15
Identities = 114/487 (23%), Positives = 199/487 (40%), Gaps = 47/487 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEF-SMKSNAKVGTVIGKVKAVDPDLGQN----- 492
L V + L+D ND+ P F S L + S+ + T++ V A D DL N
Sbjct: 2689 LSGTATVYIYLIDINDSPPKFDASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQI 2748
Query: 493 -GMVLYD---LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER 548
+ +YD + TS + F +NP G +++ E S + N
Sbjct: 2749 VSVSVYDEDDVDITSFFDYRTVFSLNPTNGNITLTSPVDREVTEKFVFSISARDLNSQNP 2808
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF---WVGSNVGIGTSV-GQIRV--NDAFE 602
+ + +VT + P F F + + G G+ + G + D
Sbjct: 2809 IFGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGL 2868
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTN 661
+V Y + + GVP +++ +G +T++ + R +P + +A+ + +L+
Sbjct: 2869 NGEVMYIIQN--PSGVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTSIP 2926
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LI 720
+ ++D ND V +H+ I ++ GA + F+ N + G+G V + LI
Sbjct: 2927 VYLEIIDNNDNNPVFGAQSHTTTI--IESEPIGAFV---FNVNATDADSGGSGRVTYSLI 2981
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI--SGAGIYQVTIYIE 778
T + + G I + +D+E + + +TV A N G S G V + +
Sbjct: 2982 GGDGKFTIN---QDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVL 3038
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE--GTNALFMYTLFGE---- 832
D N+ PPV T F ++ IG E+ +I+A D D+ N Y +
Sbjct: 3039 DANEFPPV---VTQPIFTIDEGGIGGEVV--GVIEAYDPDDPDDPNQSLYYVVVSSQPEV 3093
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKI---MYKLSLVARDTGG--LSSEAELIIMIGDEN 887
G +F ++ TG + G LDR+ + L ++ D G L + II I D N
Sbjct: 3094 GGTLFIINNATGEIITTGP-LDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYINDLN 3152
Query: 888 DNKPEFN 894
DN+P F+
Sbjct: 3153 DNQPTFD 3159
Score = 85.0 bits (201), Expect = 1e-14
Identities = 90/323 (27%), Positives = 149/323 (46%), Gaps = 41/323 (12%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTP----YHVTVDELTPTGEKAFIFLI----API 124
G Q A L VTV DVNDN P+F++ P Y +++E TG FI + A
Sbjct: 926 GDGQDIAPLMVTV--TDVNDNNPVFINRPIDNIYRGSINENDQTG--TFIVQVSTTDADS 981
Query: 125 GPSLTIPLTVPRG-----LTIFKDIRAFDRDK---PNTPNSDVHYSIVSGNDDGHFALES 176
G + + ++ G TI A + PNTP + S+ + N A +
Sbjct: 982 GSNAAVTYSIISGNINNVFTINPTSGAITNTQILGPNTPQTYT-LSVRATNPTPGVAPAT 1040
Query: 177 SHKPVLLLRKVLDYDAGDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
++ V D + F V + ++ + I A D+D+ G L
Sbjct: 1041 GTSTSTVIITVNDVNDSPPRFSDDEFTVFINEAAQVGTTVT---RITATDEDIPEGDRLT 1097
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
Y + +GN F ++ V+G + L ++LD L+++HNL ++A+ P ++A
Sbjct: 1098 YIITAGNTGGHFQINPVSGDVTLLRQLDRELESQHNLT-------IRATDQGAPPQSATT 1150
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+++ +LD NDN P++ Y SI+EN+P VLQV+ATD DQG N + ++ +++
Sbjct: 1151 TLKVIVLDFNDNAPQWSPQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNANN 1210
Query: 351 A-FSIDPRSGWLTVRNQTVLDRE 372
F ID + +R L+RE
Sbjct: 1211 VPFVIDDQG---NIRTSGPLNRE 1230
Score = 84.6 bits (200), Expect = 2e-14
Identities = 115/468 (24%), Positives = 196/468 (41%), Gaps = 45/468 (9%)
Query: 444 NVEVTLL--DANDNNPVFVP--SNLYEFSMKSNAKVGTVI-GKVKAVDPDLGQNGMVLYD 498
N +VT+L D NDN+P F P + + + G+ I G + A+DPDLG NG V+Y
Sbjct: 2816 NAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGLNGEVMYI 2875
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVT 556
+Q S + +T I+ NTG +++ + E + L V A D+ PS + V
Sbjct: 2876 IQNPSGVPVT----IDQNTGQLTLLVTVDREQQPWVNLTVLAVDK-GTPSLN--TSIPVY 2928
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
+E+ N P F + + + IG V + DA V+Y L+ G
Sbjct: 2929 LEIIDNNDNN----PVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGG- 2983
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL----QENANLSIVTNATVHVVDVN 670
+G F + + SGVIT++ + + + + A + + T V+V+D N
Sbjct: 2984 -DG-KFTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDAN 3041
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDD 729
+ V+ + IF + E G + + + ++ + ++++Q +V
Sbjct: 3042 EFPPVVTQP-----IFTIDEGGIGGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGT 3096
Query: 730 IAIAED--GTIFTQKPLDREKR-DVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ I + G I T PLDR+ R+ + + ++ G + IYI D NDN P
Sbjct: 3097 LFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYINDLNDNQP 3156
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
F+ Y+ ++E D II D N+ Y + G V + G+
Sbjct: 3157 TFDLPLYDVTVVEGQ------YSDPIITVVANDPDQNSNLRYEILGGNLNNTFVLVDGGL 3210
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+ LD E Y L++V D G + + + D ND+ P F
Sbjct: 3211 IPV--KPLDFETFTNYNLTVVVTDDSGNRDTTYVAVTVTDANDHNPTF 3256
Score = 84.2 bits (199), Expect = 2e-14
Identities = 115/489 (23%), Positives = 194/489 (39%), Gaps = 55/489 (11%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+ + N A L + + EN G+ + ++ D D+ G + Y + + P
Sbjct: 605 VRITDVNDIAPTFTNLPNITYVFENATFGSELYQVITTDEDTFYGGFVTYSIS--LVTPS 662
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG----NLNDNISVR 1032
+ SA YF I E G + +A SL E ++ + + A D G +L+ ++
Sbjct: 663 TPGSAP----NNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDYGTGDTSLSSTATLT 718
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
V V ++ D PVF T Y+ + E + + ATD D +TY + SD+
Sbjct: 719 VSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGNIITYNLVVSDSQGY 778
Query: 1093 FEISPLTGVLSVNGELDRETE---DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F I TG+++VN ++DR+ Y L V A + ND P
Sbjct: 779 FVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQVSFNVTVSPANDEPP 838
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIP---VYKATIEENAPIGTTVAKVFANDTDF 1206
F PE+ +++ ++ + + +T+ + G +V + T
Sbjct: 839 MFD--QNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSLQNGNSVP-FRVSPTQV 895
Query: 1207 IGNGNGLILYSLP---QRKNQQNLGLPSLSST----AILMVTVADVPDEVEMSDKPVFIS 1259
+G+G IL + P + Q L L ++ A LMVTV DV D + PVFI+
Sbjct: 896 VGSGTVDILITQPLDFENNQQYTLQLQAVDGDGQDIAPLMVTVTDVND-----NNPVFIN 950
Query: 1260 R----YYELEIEENVNAPVELVSLNLTE--HYENFKMRYYILNENDTDIRRTFVIDPRNG 1313
R Y I EN +V ++ T+ N + Y I++ N I F I+P +G
Sbjct: 951 RPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGN---INNVFTINPTSG 1007
Query: 1314 TLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDV 1373
+ + TY + VRA V V++ + DV
Sbjct: 1008 AITNTQILGPNTPQTYTLSVRATNP-------------TPGVAPATGTSTSTVIITVNDV 1054
Query: 1374 NDNSPKFTN 1382
ND+ P+F++
Sbjct: 1055 NDSPPRFSD 1063
Score = 82.2 bits (194), Expect = 1e-13
Identities = 117/456 (25%), Positives = 177/456 (38%), Gaps = 54/456 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ P T ++ LNA D D+G G I Y F S + V Y + E
Sbjct: 1377 LPEDSPFQTLVVDLNATDPDNGNTGLIIYSFES------LSRTQGPFTVDPYTGVVEIST 1430
Query: 1000 HVIVARSLPPESEFRLNISALD----GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ R + E+ + + A+D G + +V V V DVND+ P F+ Y ++
Sbjct: 1431 TAGLDRET--QDEYTMIVIAVDQPASGQPMTGTATVSVIVTDVNDNAPTFRDISYEESIF 1488
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + V A D D G NA + Y I + + F + + + LDRE +D+
Sbjct: 1489 ENHPLGSNILTVQADDPDLGVNAVVLYRIISGNNNNLFNVDGQGNINLGSTPLDREMQDQ 1548
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y L V A N D+ND +P F + + P+ E S
Sbjct: 1549 YFLIVQAY-NSDLSVGTNEVPVIINILDINDVTPLF----QQQNYYRPDLSENSPSG-TP 1602
Query: 1176 VMMIPVYKATIE-----ENAPIGTTVAKVFANDTDFIG-NG-----NGLILYSLPQRKNQ 1224
V+ + ++ + + IG +DT I NG +G +++ R
Sbjct: 1603 VLQVFAQDQDLDLAGDVQYSLIGNPNFLTINSDTGVISVNGPIADLSGSRNFTMTVRATD 1662
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
Q P L A + VTV D D V + P+F Y + ENVNA + ++ T +
Sbjct: 1663 Q--ASPFLRGVATVTVTVVD--DTVTI---PIFTLSRYPATVIENVNADTPVTRVSATLN 1715
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
+ Y I + F ID G + + DREV+D Y V A +
Sbjct: 1716 GNPAGITYAIDPNASPAVLEIFKIDENTGHITTEGAIDREVEDFYAFTVFAYHE------ 1769
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ V G T V V I D NDN P+F
Sbjct: 1770 --------DSVAPGST----SVWVNILDENDNPPEF 1793
Score = 81.4 bits (192), Expect = 2e-13
Identities = 118/486 (24%), Positives = 207/486 (42%), Gaps = 75/486 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+P+ T ++++ A D D G N + + N+ +P FVI+++ G
Sbjct: 1175 ILENVPLNTFVLQVVATDADQGTNADLSFTINNANNVP--------------FVIDDQ-G 1219
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNL----NDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
++ + L E+ ++ ++ LD G+ N +V + + DVND PV + Y F
Sbjct: 1220 NIRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFT 1279
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E +G+V ATD D + LTY P+D D + ++G + N +LD +
Sbjct: 1280 VSEDVNFNTFVGQVTATDPDL--SGTLTYTFVPADPDFSY----ISGTIRTNTQLDANQQ 1333
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHP------EA 1165
Y +TV A D DVN+ +P F + + L P +
Sbjct: 1334 QVYQMTVFASDG---VQNSQSAPVTINVLDVNNQAPSFGLGTYVKSLPEDSPFQTLVVDL 1390
Query: 1166 DELSNHNFESVMMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKN 1223
+ N + ++I +++ P + V + T + + +
Sbjct: 1391 NATDPDNGNTGLIIYSFESLSRTQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVD 1450
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNL 1281
Q G P ++ TA + V V DV D + P F YE I EN + + + V +
Sbjct: 1451 QPASGQP-MTGTATVSVIVTDVND-----NAPTFRDISYEESIFENHPLGSNILTVQADD 1504
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRAERQKY 1340
+ N + Y I++ N+ ++ F +D + G + L +P DRE++D Y +IV+A Y
Sbjct: 1505 PDLGVNAVVLYRIISGNNNNL---FNVDGQ-GNINLGSTPLDREMQDQYFLIVQA----Y 1556
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN--RPLVTAIPTTAPFG 1398
+ +L + +V V++ I D+ND +P F N RP + +P G
Sbjct: 1557 NSDL-------------SVGTNEVPVIINILDINDVTPLFQQQNYYRP---DLSENSPSG 1600
Query: 1399 YQVMQL 1404
V+Q+
Sbjct: 1601 TPVLQV 1606
Score = 77.4 bits (182), Expect = 3e-12
Identities = 91/355 (25%), Positives = 144/355 (40%), Gaps = 53/355 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT I++++ D DSG N + Y S + F IN G
Sbjct: 961 INENDQTGTFIVQVSTTDADSGSNAAVTYSIISG-------------NINNVFTINPTSG 1007
Query: 1000 HVIVARSLPPESE--FRLNISALDG------GNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ + L P + + L++ A + +V + V DVND P F +
Sbjct: 1008 AITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVNDVNDSPPRFSDDEFT 1067
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
+ EA + ++ ATD D + LTY I +T F+I+P++G +++ +LDRE
Sbjct: 1068 VFINEAAQVGTTVTRITATDEDIPEGDRLTYIITAGNTGGHFQINPVSGDVTLLRQLDRE 1127
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA---FDELLEWKHPEADEL 1168
E ++ LT+ A D G D NDN+P++ D +LE +
Sbjct: 1128 LESQHNLTIRATDQG-APPQSATTTLKVIVLDFNDNAPQWSPQSYVDSILE-------NV 1179
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN---QQ 1225
+ F V+ + A NA + T+ AN+ F+ + G I S P + Q
Sbjct: 1180 PLNTF--VLQVVATDADQGTNADLSFTINN--ANNVPFVIDDQGNIRTSGPLNRETVPQY 1235
Query: 1226 NL-------GLPSLSST--AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
N G P + A + + + DV DE PV YE + E+VN
Sbjct: 1236 NFLVTVLDNGSPQQAGNPPATVTINILDVNDE-----PPVLDRNSYEFTVSEDVN 1285
Score = 77.4 bits (182), Expect = 3e-12
Identities = 57/169 (33%), Positives = 88/169 (52%), Gaps = 7/169 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLGV A + Y +ISGN+ LF++D G++ L LD E +Q F++ VQ
Sbjct: 1500 VQADDPDLGVNAVVLYRIISGNNNNLFNVDG-QGNINLGST-PLDRE--MQDQYFLI-VQ 1554
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDKDQG 336
A + + T + V I +LD+ND P F+ ++Y + EN P+G VLQV A D+D
Sbjct: 1555 AYNSDLSVGTNEVPVIINILDINDVTPLFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLD 1614
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+ Y L +I+ +G ++V N + D + M V A +
Sbjct: 1615 LAGDVQYSLIGNPNFLTINSDTGVISV-NGPIADLSGSRNFTMTVRATD 1662
Score = 77.0 bits (181), Expect = 4e-12
Identities = 57/213 (26%), Positives = 93/213 (43%), Gaps = 20/213 (9%)
Query: 943 NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI 1002
N+P+G A D D+G+N Q+ + +S F G ++
Sbjct: 1810 NVPVGL----FRATDPDAGINAQMTFS-----------ISGAGSNFFNVFQTANGGGTIV 1854
Query: 1003 VARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
V L E + ++L ++A DGGN L+ + + + V DVND++P++ + Y ++ E
Sbjct: 1855 VTSPLDRERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENN 1914
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
+T + V D D + N Y I D FEI+ G ++V+ LDRE ++ Y L
Sbjct: 1915 FTSNPIITVMVNDLDLPSSNNFEYSIIAGDPMGMFEINS-NGEITVSSLLDREQQETYQL 1973
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
T+ D D NDN+P F
Sbjct: 1974 TIELIDQTNSPPARTTTLAIITVGDENDNTPIF 2006
Score = 76.2 bits (179), Expect = 7e-12
Identities = 56/174 (32%), Positives = 83/174 (47%), Gaps = 9/174 (5%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P + A+D DLG+ + Y +I ++D G L L + +D E N VL
Sbjct: 2856 PGNLLALDPDLGLNGEVMY-IIQNPSGVPVTIDQNTGQLTLL--VTVDREQQPWVNLTVL 2912
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V P V +E++D NDN P F + +I+E+ P G V V ATD D
Sbjct: 2913 AVDKG---TPSLNTSIPVYLEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDAD 2969
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
G +G TY L G F+I+ SG +T+ Q +D+E S + V+A++ NP
Sbjct: 2970 SGGSGRVTYSLIGGDGKFTINQDSGVITLLQQ--VDKETQSQHMLTVFARD-NP 3020
Score = 74.1 bits (174), Expect = 3e-11
Identities = 107/427 (25%), Positives = 180/427 (42%), Gaps = 73/427 (17%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSL-DSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D G+ A + + ISG F++ + NG + LD E + + L V A
Sbjct: 1818 ATDPDAGINAQMTFS-ISGAGSNFFNVFQTANGGGTIVVTSPLDRERQ---DFYQLTVTA 1873
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+ NP ++ + I + D+NDN P + + Y SI EN ++ VM D D +
Sbjct: 1874 TDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSS 1933
Query: 339 GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
F Y + DP G F I+ +G +TV ++LDRE + ++ + +
Sbjct: 1934 NNFEYSIIAGDPMGMFEIN-SNGEITV--SSLLDREQQETYQLTIELID----------- 1979
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+TN+P +TT + VG + +N + E + + V+VT ++ N
Sbjct: 1980 ------------QTNSPPARTTTLAIITVGDENDNTPIFAE---TVIRVDVTEGPSSQNI 2024
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
PV++ + A D DLG N ++Y + + S F+INP
Sbjct: 2025 PVYM---------------------LTANDIDLGLNRDIIYAI---GSQQPQSHFQINPE 2060
Query: 517 TGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
TG +S + E + L V A+DQ +P+E R A V + V G + D
Sbjct: 2061 TGMISTTTALDWETISEYTLIVTATDQ--SPTEPRTGTATVIVSVNDINDGAPMFVRDVY 2118
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL---HGYEEGVPFAVEERSGVI 629
G PY V V + + + D + V+Y ++ + +G P V + G
Sbjct: 2119 G-PYS--VVEEVS-NSYIDSFQATDTDQGLAGTVTYSVIVSVNDINDGAPMFVRDVYGPY 2174
Query: 630 TVVDDLS 636
+VV+++S
Sbjct: 2175 SVVEEVS 2181
Score = 72.5 bits (170), Expect = 8e-11
Identities = 125/464 (26%), Positives = 177/464 (38%), Gaps = 50/464 (10%)
Query: 443 VNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V++ + L N P FV P+ + N +G +I AVD D+G NG+V Y
Sbjct: 3448 VDLRINYLGLNAP-PSFVRPNQGSTVFITENNPLGQLIINAFAVDDDVGANGVVDY---- 3502
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+I F N V + + L V +D N + Y V + VT
Sbjct: 3503 ----SILPNFDYNGGLIPVKPLDFETFT-NYNLTVVVTDDSGN-RDTTY----VAVTVTD 3552
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF---EQNDVSYDLLHGYEEGV 618
N +PD Y V N GT VG + D E D+ Y +L G G
Sbjct: 3553 ANDHNPTFVPD----QYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLG- 3607
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVL 676
F + +G+IT L R Y A EN ATV ++ DVND
Sbjct: 3608 NFTINSTTGIITTATILDREKTSEYVLTIGA--ENPVGGTTGTATVSIIVRDVNDNTPTF 3665
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTDDIAIAED 735
+P V N+ + H N GNG + N+ + T D
Sbjct: 3666 ---EENPYTSTVTTNTLLVDV----HANDPDEGGNGIVIYEIVSGNEDNRFTID---NRT 3715
Query: 736 GTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I PL+ + Y + VI + + + I N PP F
Sbjct: 3716 GVITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRINYLGLN-APPSFVRPNQGS 3774
Query: 795 --FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGD 851
FI EN+ +G + + N A D D G N + Y++ F +D TG + +
Sbjct: 3775 TVFITENNPLG--LLIINAF-AVDDDVGANGVVDYSILPNFDYSDFTIDPVTGDITIL-V 3830
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
S DRE K Y L++VA D G LS+ + +I + DENDN P F
Sbjct: 3831 SADREIKDSYTLTVVATDRGDPNLSTSSTFVIRVLDENDNNPAF 3874
Score = 71.7 bits (168), Expect = 1e-10
Identities = 71/263 (26%), Positives = 111/263 (42%), Gaps = 19/263 (7%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFA-LDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
R L+GTA I + + D L + IPE+ P T + + A D D LN
Sbjct: 2685 RNPPLSGTATVYIYLIDINDSPPKFDASFLDQIISIPEDTPGNTIVTTVTATDDD--LNS 2742
Query: 965 QIRYEFNS-EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALD 1021
I Y+ S VY + + F +N +G++ + + E +F +ISA D
Sbjct: 2743 NINYQIVSVSVYDEDDVDITSFFDYRTVFSLNPTNGNITLTSPVDREVTEKFVFSISARD 2802
Query: 1022 GGNLN-------DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT----RRVLGKVDAT 1070
+ N +N V + + D+ND+ P F+ F + + + + G + A
Sbjct: 2803 LNSQNPIFGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLAL 2862
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G N + Y IQ + + +P I TG L++ +DRE + LTV+A D G
Sbjct: 2863 DPDLGLNGEVMYIIQ-NPSGVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKG-TPS 2920
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYA 1153
D NDN+P F A
Sbjct: 2921 LNTSIPVYLEIIDNNDNNPVFGA 2943
Score = 70.9 bits (166), Expect = 2e-10
Identities = 174/797 (21%), Positives = 309/797 (38%), Gaps = 103/797 (12%)
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+G P V + G +VV+++S N + F+A + ++ + V V D+ND +
Sbjct: 2108 DGAPMFVRDVYGPYSVVEEVS--NSYIDSFQATDTDQGLAGTVTYSVIVSVNDINDGAPM 2165
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
++ + P + V E + + I T+ G V + + Q +D I
Sbjct: 2166 FVRDVYGP--YSVVEEVSNSYIDSFQATDTDQ---GLAGMVTYSVIGQY--SDLFFIQPQ 2218
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
+ T +P DR I EFN +T+ D P + G
Sbjct: 2219 TGVLTIRP-DR----ALDYETITEFN-----------ITVVATDMG--VPALSSSPQTGV 2260
Query: 796 --IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I + + E + I D G AL TL G + +++++T + + I ++
Sbjct: 2261 LTIRPDRALDYETITEFNITVVATDMGNPALSSSTLVGIN--VININDHTPIFEGIPYTI 2318
Query: 854 DREKKIMY-KLSLVAR---DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
K I L+ V R D G+ E I G+ DN +Q ++ E K
Sbjct: 2319 TLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGN-TDNIFRIDQTIDSMGAT---EEK 2374
Query: 910 LNGT-AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
T G +I + N + + + +NI G+ + A D D+G+ G++RY
Sbjct: 2375 TGQTLVGINVINI---NDHTPIFEGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRY 2431
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDG-GNLND 1027
+ + + R + G V V + L +RL + A D G++
Sbjct: 2432 QITD----------GNTDNIFRIDQTTGQTGEVFV-QGLLETGTYRLVVEARDTPGDIPS 2480
Query: 1028 N----ISVRVFVKDVNDHFPVFK-KTWYNFNVEEAQYTRRVLGKVDATDA-DFGQNANLT 1081
+ ++ + V D+ D P F + + NV E + + + A + L
Sbjct: 2481 SRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINSDATGQLV 2540
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
Y I D+ F I+ L+ + VNG LDRET+D Y V+ D+
Sbjct: 2541 YTITGPDSQT-FMINQLSAGIQVNGPLDRETKDFYEFGVIVTDS---MGLTAMGTVHINV 2596
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADE-------LSNHNFESVMMIPVYKATIEENAPIGT 1194
DVND +P F D + + PE +S ++ + + + E+ IG
Sbjct: 2597 LDVNDFAPAFN--DSVYNFTIPENSPGGYYVGGVSAYDLDGDNVNFFIQTGGEDKFDIGG 2654
Query: 1195 TVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
T + + Y+L + +L P LS TA + + + D+ D D
Sbjct: 2655 TSGTITVTPGAVLDREEKPF-YTLTVMVS--DLRNPPLSGTATVYIYLIDINDSPPKFDA 2711
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILN-----ENDTDI------R 1303
F+ + + I E+ + ++ T+ N + Y I++ E+D DI R
Sbjct: 2712 S-FLDQI--ISIPEDTPGNTIVTTVTATDDDLNSNINYQIVSVSVYDEDDVDITSFFDYR 2768
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD 1363
F ++P NG + L DREV + + + A R+L +++ + G ++ +
Sbjct: 2769 TVFSLNPTNGNITLTSPVDREVTEKFVFSISA------RDLN------SQNPIFGTSQEN 2816
Query: 1364 VKVVVRIKDVNDNSPKF 1380
+V + I D+NDN P F
Sbjct: 2817 AQVTILITDINDNHPAF 2833
Score = 69.7 bits (163), Expect = 6e-10
Identities = 109/438 (24%), Positives = 174/438 (39%), Gaps = 69/438 (15%)
Query: 929 LDVDQLGPLFL--------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
LD++ + PLF + EN P GT ++++ A D D L G ++Y
Sbjct: 1574 LDINDVTPLFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLIGN------- 1626
Query: 981 LSADALEVKRYFVINERHGHVIV---ARSLPPESEFRLNISALDGGN--LNDNISVRVFV 1035
+ IN G + V L F + + A D + L +V V V
Sbjct: 1627 --------PNFLTINSDTGVISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTV 1678
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D P+F + Y V E + +V AT G A +TY I P+ + EI
Sbjct: 1679 VDDTVTIPIFTLSRYPATVIENVNADTPVTRVSATLN--GNPAGITYAIDPNASPAVLEI 1736
Query: 1096 SPL---TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
+ TG ++ G +DRE ED Y TV A D NDN P+F
Sbjct: 1737 FKIDENTGHITTEGAIDREVEDFYAFTVFAYHE--DSVAPGSTSVWVNILDENDNPPEFI 1794
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE---NAPIGTTVAKVFANDTDFI-- 1207
P + N + + +++AT + NA + +++ +N +
Sbjct: 1795 TV--------PPSPVSVRENTGGNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQT 1846
Query: 1208 GNGNGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
NG G I+ + P + +Q+ G PSLSS+ L +TV DV D + P++
Sbjct: 1847 ANGGGTIVVTSPLDRERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVND-----NYPIW 1901
Query: 1258 ISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
YE I EN + P+ V +N + + Y I+ D F I+ NG +
Sbjct: 1902 TRNVYEGSINENNFTSNPIITVMVNDLDLPSSNNFEYSII---AGDPMGMFEIN-SNGEI 1957
Query: 1316 YLVRSPDREVKDTYEVIV 1333
+ DRE ++TY++ +
Sbjct: 1958 TVSSLLDREQQETYQLTI 1975
Score = 69.3 bits (162), Expect = 8e-10
Identities = 69/249 (27%), Positives = 105/249 (42%), Gaps = 15/249 (6%)
Query: 217 PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
PI AI+ D L Y I+G D + F ++ ++ + + LD + + + V
Sbjct: 2527 PIRAINSD--ATGQLVYT-ITGPDSQTFMINQLSAGIQVNGPLDRETKDFYEFGVIVTDS 2583
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
TA V I +LD+ND P F YN +I EN P G+ V V A D D G
Sbjct: 2584 MGL-------TAMGTVHINVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLD-G 2635
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFA 395
+N F Q + F I SG +TV VLDRE + V + NP + GT
Sbjct: 2636 DNVNFFIQTGG-EDKFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTAT 2694
Query: 396 DSQRIAKWRRQPLETNAP-LEKTTYVFPDKVG-TKTENIEYYDEQLMSFVNVEVTLLDAN 453
+ P + +A L++ + D G T + D+ L S +N ++ +
Sbjct: 2695 VYIYLIDINDSPPKFDASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQIVSVSVY 2754
Query: 454 DNNPVFVPS 462
D + V + S
Sbjct: 2755 DEDDVDITS 2763
Score = 68.1 bits (159), Expect = 2e-09
Identities = 56/221 (25%), Positives = 97/221 (43%), Gaps = 10/221 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS---KLSADALEVKRYFVINE 996
+ +N PI T + +++ ++ + I +++ +P S + S A + F IN
Sbjct: 1894 VNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSSNNFEYSIIAGDPMGMFEINS 1953
Query: 997 RHGHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+G + V+ L E + ++L I +D N + V D ND+ P+F +T
Sbjct: 1954 -NGEITVSSLLDREQQETYQLTIELIDQTNSPPARTTTLAIITVGDENDNTPIFAETVIR 2012
Query: 1052 FNVEEAQYTRRV-LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+V E ++ + + + A D D G N ++ Y I F+I+P TG++S LD
Sbjct: 2013 VDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYAIGSQQPQSHFQINPETGMISTTTALDW 2072
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
ET +Y L V A D D+ND +P F
Sbjct: 2073 ETISEYTLIVTATDQSPTEPRTGTATVIVSVNDINDGAPMF 2113
Score = 67.3 bits (157), Expect = 3e-09
Identities = 84/318 (26%), Positives = 124/318 (38%), Gaps = 20/318 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT---VPRGL 138
+VT+ I DVND P+ Y TV E F+ + P L+ LT VP
Sbjct: 1256 TVTINILDVNDEPPVLDRNSYEFTVSE--DVNFNTFVGQVTATDPDLSGTLTYTFVPADP 1313
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ 198
+ N Y + DG S PV + VLD + F
Sbjct: 1314 DFSYISGTIRTNTQLDANQQQVYQMTVFASDG--VQNSQSAPVTI--NVLDVNNQAPSFG 1369
Query: 199 LVIMASGKRIHKEILFPE---PIHAIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLF 254
L K + ++ F ++A D D G + Y S + F++D G +
Sbjct: 1370 LGTYV--KSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSRTQGPFTVDPYTGVVE 1427
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
+ LD E + V+ V P+ T A V + + D+NDN P F Y S
Sbjct: 1428 ISTTAGLDRETQDEYTMIVIAVDQPASGQPM-TGTATVSVIVTDVNDNAPTFRDISYEES 1486
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
I EN P G ++L V A D D G N Y++ + F++D + G + + T LDRE
Sbjct: 1487 IFENHPLGSNILTVQADDPDLGVNAVVLYRIISGNNNNLFNVDGQ-GNINL-GSTPLDRE 1544
Query: 373 AHSSLRMKVYAKETNPSV 390
+ V A ++ SV
Sbjct: 1545 MQDQYFLIVQAYNSDLSV 1562
Score = 66.5 bits (155), Expect = 5e-09
Identities = 115/519 (22%), Positives = 200/519 (38%), Gaps = 68/519 (13%)
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTI 918
+ Y +SLV T G + I D EE + + + GT ++
Sbjct: 652 VTYSISLVTPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDYGTGDTSL 711
Query: 919 IEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
L++ P+F+ IPE +P+G+T+ + A D DS I Y
Sbjct: 712 SSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGNIITYNL- 770
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE-----FRLNISALD---GG 1023
+ +D+ + YFVI++ G + V + ++ + L +SA++ GG
Sbjct: 771 ---------VVSDS---QGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGG 818
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTY 1082
+S V V ND P+F + Y+ ++ E A ++ + D D ++ +T
Sbjct: 819 VSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTV 878
Query: 1083 FIQPSDTDLPFEISPLTGV------LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
+Q + +PF +SP V + + LD E +Y L + A D
Sbjct: 879 SLQ-NGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDG----DGQDIAP 933
Query: 1137 XXXXXXDVNDNSPKFY--AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
DVNDN+P F D + E D+ ++ + A NA +
Sbjct: 934 LMVTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTF----IVQVSTTDADSGSNAAVTY 989
Query: 1195 TVAKVFANDTDFIGNGNGLI------------LYSLPQRKNQQNLGL-PSL-SSTAILMV 1240
++ N+ I +G I Y+L R G+ P+ +ST+ +++
Sbjct: 990 SIISGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVII 1049
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT-EHYENFKMRYYILNEND 1299
TV DV D P F + + I E + + T E YI+ +
Sbjct: 1050 TVNDVND-----SPPRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITAGN 1104
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
T F I+P +G + L+R DRE++ + + +RA Q
Sbjct: 1105 TG--GHFQINPVSGDVTLLRQLDRELESQHNLTIRATDQ 1141
Score = 65.3 bits (152), Expect = 1e-08
Identities = 93/344 (27%), Positives = 143/344 (41%), Gaps = 36/344 (10%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA-FIFLIAPI---GP 126
G G +S+ ++TV + ++ D P+F++TPY VT+ E P G I P G
Sbjct: 705 GTGDTSLSSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGN 764
Query: 127 SLTIPLTVP--RGLTIFKDIRAF-------DRDKPNTPNS-DVHYSIVSGNDDG-HFALE 175
+T L V +G + DRD P P + + S V + G FA
Sbjct: 765 IITYNLVVSDSQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQV 824
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
S + V + D+ + ++ ++ P I D DL +T+ L
Sbjct: 825 SFNVTVSPAND--EPPMFDQNSYSASIPESASVNSQL--PITITVNDGDLITDSTVTVSL 880
Query: 236 ISGNDRKL-FSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+GN S V GS ++ + LD E+N Q + LQ+QA + A +
Sbjct: 881 QNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQ---YTLQLQAVDGDGQ---DIAPL 934
Query: 293 EIELLDLNDNLPEF---EVD-FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--D 346
+ + D+NDN P F +D Y SI EN G ++QV TD D G N TY +
Sbjct: 935 MVTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISG 994
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
+ F+I+P SG +T N +L + + V A P V
Sbjct: 995 NINNVFTINPTSGAIT--NTQILGPNTPQTYTLSVRATNPTPGV 1036
Score = 64.9 bits (151), Expect = 2e-08
Identities = 50/174 (28%), Positives = 85/174 (48%), Gaps = 13/174 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ D D G A + Y +ISGN +F+++ +G++ + L + T+ L V+
Sbjct: 974 VSTTDADSGSNAAVTYSIISGNINNVFTINPTSGAITNTQILGPNTPQ-----TYTLSVR 1028
Query: 278 ASQLNNPLK----TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
A+ + T+ + V I + D+ND+ P F D + + I E G +V ++ ATD+
Sbjct: 1029 ATNPTPGVAPATGTSTSTVIITVNDVNDSPPRFSDDEFTVFINEAAQVGTTVTRITATDE 1088
Query: 334 DQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D E TY + + G F I+P SG +T+ Q LDRE S + + A +
Sbjct: 1089 DIPEGDRLTYIITAGNTGGHFQINPVSGDVTLLRQ--LDRELESQHNLTIRATD 1140
Score = 64.1 bits (149), Expect = 3e-08
Identities = 50/173 (28%), Positives = 76/173 (43%), Gaps = 12/173 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D G + YE++SGN+ F++D+ G + L L+ N + L V
Sbjct: 3683 VHANDPDEGGNGIVIYEIVSGNEDNRFTIDNRTGVITLVNPLESQLIRN-----YTLVVI 3737
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEV---DFYNISIVENLPNGFSVLQVMATDKD 334
L NP + V++ + L N P V + I EN P G ++ A D D
Sbjct: 3738 GHDLGNPQLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNPLGLLIINAFAVDDD 3797
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG Y + + F+IDP +G +T+ DRE S + V A +
Sbjct: 3798 VGANGVVDYSILPNFDYSDFTIDPVTGDITI--LVSADREIKDSYTLTVVATD 3848
Score = 58.4 bits (135), Expect = 1e-06
Identities = 70/282 (24%), Positives = 109/282 (38%), Gaps = 24/282 (8%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK--AFIFLIAPIGPSLT-IP 131
N+ + Y++VTV D ND+ P F+ Y +TV E P G + A I + P T I
Sbjct: 3236 NRDTTYVAVTV--TDANDHNPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDII 3293
Query: 132 LTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
T+ G TI Y + G ++ + +++R
Sbjct: 3294 YTILTGNGLGNFTINSTTGIITTATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRD 3353
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
V D +E + + + ++ HA D D G + YE++SGN+ F +
Sbjct: 3354 VNDNTPTFEENPYISTVTTNTLLVDV------HANDPDEGGNGIVIYEIVSGNEDNRFQI 3407
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D+ G + L LD N + L V L NP + V++ + L N P
Sbjct: 3408 DNRTGVITLVNPLDSQLIRN-----YTLVVIGHDLGNPRLQSNTTVDLRINYLGLNAPPS 3462
Query: 307 EV---DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
V + I EN P G ++ A D D G NG Y +
Sbjct: 3463 FVRPNQGSTVFITENNPLGQLIINAFAVDDDVGANGVVDYSI 3504
Score = 58.0 bits (134), Expect = 2e-06
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 19/164 (11%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN--NPL-KTAQ--ARVEIE 295
R +FSL+ NG++ L +D + FV + A LN NP+ T+Q A+V I
Sbjct: 2768 RTVFSLNPTNGNITLTSPVDREVTEK-----FVFSISARDLNSQNPIFGTSQENAQVTIL 2822
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSV-----LQVMATDKDQGENGEFTYQLDDPKG 350
+ D+NDN P F+ I+ LP F ++A D D G NGE Y + +P G
Sbjct: 2823 ITDINDNHPAFQPPGTTF-ILRQLPESFGAGSPIPGNLLALDPDLGLNGEVMYIIQNPSG 2881
Query: 351 A-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+ID +G LT+ +DRE + + V A + + T
Sbjct: 2882 VPVTIDQNTGQLTL--LVTVDREQQPWVNLTVLAVDKGTPSLNT 2923
Score = 56.4 bits (130), Expect = 6e-06
Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 14/179 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I + D + LRYE++ GN F L V+G L K LD + N V
Sbjct: 3177 ITVVANDPDQNSNLRYEILGGNLNNTFVL--VDGGLIPVKPLDFETFTNYNLTVVVTDDS 3234
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ-G 336
++ V + + D ND+ P F D Y++++ EN P G V V+ D D
Sbjct: 3235 GNR-------DTTYVAVTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLP 3287
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
E + Y + + G F+I+ +G +T T+LDRE S + + A+ GT
Sbjct: 3288 EYTDIIYTILTGNGLGNFTINSTTGIIT--TATILDREKTSEYVLTIGAENPVGGTTGT 3344
Score = 55.2 bits (127), Expect = 1e-05
Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 19/164 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D+G + Y ++ D F++D V G + + D + + +++ L V A+
Sbjct: 3793 AVDDDVGANGVVDYSILPNFDYSDFTIDPVTGDITILVSADREIK-----DSYTLTVVAT 3847
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVM--------A 330
+P + + I +LD NDN P F D N IV NL N F + A
Sbjct: 3848 DRGDPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNL-NVFENANISDLVGTVDGA 3906
Query: 331 TDKDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDRE 372
D D G NG+ Y + D G F I+ +G +TV LDRE
Sbjct: 3907 IDLDLGANGQIFYHIVDSTVGGIFVINSTTGVVTVNG--TLDRE 3948
Score = 53.2 bits (122), Expect = 5e-05
Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 16/137 (11%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL--KTAQA 290
Y +++GN F+++S G + LD + + + +VL + A NP+ T A
Sbjct: 3598 YTILTGNGLGNFTINSTTGIITTATILDRE-----KTSEYVLTIGAE---NPVGGTTGTA 3649
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDP 348
V I + D+NDN P FE + Y ++ N ++ V A D D+G NG Y++ +
Sbjct: 3650 TVSIIVRDVNDNTPTFEENPYTSTVTTNT----LLVDVHANDPDEGGNGIVIYEIVSGNE 3705
Query: 349 KGAFSIDPRSGWLTVRN 365
F+ID R+G +T+ N
Sbjct: 3706 DNRFTIDNRTGVITLVN 3722
Score = 51.6 bits (118), Expect = 2e-04
Identities = 41/137 (29%), Positives = 68/137 (49%), Gaps = 16/137 (11%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL--KTAQA 290
Y +++GN F+++S G + LD + + + +VL + A NP+ T A
Sbjct: 3294 YTILTGNGLGNFTINSTTGIITTATILDRE-----KTSEYVLTIGAE---NPVGGTTGTA 3345
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDP 348
V I + D+NDN P FE + Y ++ N ++ V A D D+G NG Y++ +
Sbjct: 3346 TVSIIVRDVNDNTPTFEENPYISTVTTNT----LLVDVHANDPDEGGNGIVIYEIVSGNE 3401
Query: 349 KGAFSIDPRSGWLTVRN 365
F ID R+G +T+ N
Sbjct: 3402 DNRFQIDNRTGVITLVN 3418
Score = 50.8 bits (116), Expect = 3e-04
Identities = 67/271 (24%), Positives = 109/271 (40%), Gaps = 19/271 (7%)
Query: 82 SVTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSLTIPLTVP 135
S+ VY+E D NDN P+F + T+ E P G AF+F + A G S + ++
Sbjct: 2924 SIPVYLEIIDNNDNNPVFGAQSHTTTIIESEPIG--AFVFNVNATDADSGGSGRVTYSLI 2981
Query: 136 RG---LTIFKDIRAFDR-DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
G TI +D + + H V D+ + +S ++ VLD +
Sbjct: 2982 GGDGKFTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDAN 3041
Query: 192 AGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR---KLFSLD 247
Q + I E++ + D +L Y ++S LF ++
Sbjct: 3042 EFPPVVTQPIFTIDEGGIGGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGTLFIIN 3101
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
+ G + LD D +NL L V NP I + DLNDN P F+
Sbjct: 3102 NATGEIITTGPLDRD--NNLHPARVDLDVIVYDDGNPNLGTPTTAIIYINDLNDNQPTFD 3159
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+ Y++++VE + ++ V+A D DQ N
Sbjct: 3160 LPLYDVTVVEGQYSD-PIITVVANDPDQNSN 3189
Score = 48.8 bits (111), Expect = 0.001
Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D+G + Y ++ D NG L K LD + N V +
Sbjct: 3489 AVDDDVGANGVVDYSILPNFD--------YNGGLIPVKPLDFETFTNYNLTVVVTDDSGN 3540
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ-GEN 338
+ V + + D ND+ P F D Y++++ EN P G V V+ D D E
Sbjct: 3541 R-------DTTYVAVTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEY 3593
Query: 339 GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+ Y + + G F+I+ +G +T T+LDRE S + + A+ GT
Sbjct: 3594 TDIIYTILTGNGLGNFTINSTTGIIT--TATILDREKTSEYVLTIGAENPVGGTTGT 3648
Score = 48.4 bits (110), Expect = 0.002
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 14/175 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFV-PSNL-----YEFSMKSNAKVGTVIGKVK-AVDPD 488
D L + + +LD NDNNP F P + ++ NA + ++G V A+D D
Sbjct: 3851 DPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLD 3910
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPS 546
LG NG + Y + + T+ F IN TG V+V + E G H +++ A++
Sbjct: 3911 LGANGQIFYHI---VDSTVGGIFVINSTTGVVTVNGTLDREDIGVHTIYILATNDATYNG 3967
Query: 547 ERRYS-LAVVTIEVTRGTKGNKPD-IPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
Y+ L ++++ + T + D P F + ++ +G +V + V D
Sbjct: 3968 TGPYNVLDNISLKEVKITLLDINDNAPRFTSTVISACIPFDISLGMTVVSVAVVD 4022
Score = 48.4 bits (110), Expect = 0.002
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT-FVLQVQA 278
AID DLG + Y ++ +F ++S G + + LD + ++ +T ++L
Sbjct: 3906 AIDLDLGANGQIFYHIVDSTVGGIFVINSTTGVVTVNGTLDRE---DIGVHTIYILATND 3962
Query: 279 SQLN-----NPLKTAQAR-VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ N N L + V+I LLD+NDN P F + I ++ G +V+ V D
Sbjct: 3963 ATYNGTGPYNVLDNISLKEVKITLLDINDNAPRFTSTVISACIPFDISLGMTVVSVAVVD 4022
Query: 333 KDQGENGEFTYQLD 346
D G N Y L+
Sbjct: 4023 LDGGTNLGIAYSLN 4036
Score = 46.0 bits (104), Expect = 0.008
Identities = 103/434 (23%), Positives = 166/434 (38%), Gaps = 69/434 (15%)
Query: 987 EVKRYFVINERHGHVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFVK--DVNDH 1041
E + F IN+ G + L E+ + + +S DG +ND + ++V+ DVND
Sbjct: 556 EARSIFTINQFTGQLYALPGLDYETLGNQVIITVSVTDG--INDPVPQTIYVRITDVNDI 613
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-------FE 1094
P F V E L +V TD D +TY I P F
Sbjct: 614 APTFTNLPNITYVFENATFGSELYQVITTDEDTFYGGFVTYSISLVTPSTPGSAPNNYFS 673
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYA 1153
I G++ + L+ E +Y +TVVARD G ++ D +P F
Sbjct: 674 IGETDGIIQLATSLNYEEIQQYFVTVVARDYGTGDTSLSSTATLTVSVLNIQDTNPVFI- 732
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
N + IP E P+G+TV + A D D N +
Sbjct: 733 ------------------NTPYDVTIP-------ETLPVGSTVQTITATDPD--SNDGNI 765
Query: 1214 ILYSLPQRKNQ------QNLGLPSLSS-----TAILMVTVADVPDEVEMSDKPV-FISRY 1261
I Y+L +Q Q G+ +++S +L T + VE S V F
Sbjct: 766 ITYNLVVSDSQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQVS 825
Query: 1262 YELEIE-ENVNAPV---ELVSLNLTEHYE-NFKMRYYI-LNENDTDIRRTFVIDPRNGTL 1315
+ + + N P+ S ++ E N ++ I +N+ D T + +NG
Sbjct: 826 FNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSLQNGNS 885
Query: 1316 YLVR-SPDREV-KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDV 1373
R SP + V T ++++ Q E + Y + ++G + ++V + DV
Sbjct: 886 VPFRVSPTQVVGSGTVDILI---TQPLDFE-NNQQYTLQLQAVDGDGQDIAPLMVTVTDV 941
Query: 1374 NDNSPKFTNGNRPL 1387
NDN+P F NRP+
Sbjct: 942 NDNNPVFI--NRPI 953
Score = 46.0 bits (104), Expect = 0.008
Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 10/157 (6%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
++F +D G + E +D + E F + + V + +LD ND
Sbjct: 1735 EIFKIDENTGHITTEGAIDREVEDFYAFTVFAYH------EDSVAPGSTSVWVNILDEND 1788
Query: 302 NLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF--SIDPRS 358
N PEF V +S+ EN V ATD D G N + T+ + F +
Sbjct: 1789 NPPEFITVPPSPVSVRENTGGNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTAN 1848
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTF 394
G T+ + LDRE ++ V A + NPS+ +F
Sbjct: 1849 GGGTIVVTSPLDRERQDFYQLTVTATDGGNPSLSSSF 1885
Score = 45.2 bits (102), Expect = 0.014
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 13/130 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D D G + Y+L R +F+++ G L+ LD + N ++ V
Sbjct: 538 LNATDPD---GDPITYDLFDDEARSIFTINQFTGQLYALPGLDYET----LGNQVIITVS 590
Query: 278 ASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV-ENLPNGFSVLQVMATDKDQ 335
+ +N+P+ + + + D+ND P F + NI+ V EN G + QV+ TD+D
Sbjct: 591 VTDGINDPVPQT---IYVRITDVNDIAPTF-TNLPNITYVFENATFGSELYQVITTDEDT 646
Query: 336 GENGEFTYQL 345
G TY +
Sbjct: 647 FYGGFVTYSI 656
Score = 44.8 bits (101), Expect = 0.018
Identities = 46/167 (27%), Positives = 72/167 (43%), Gaps = 13/167 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA- 278
A D D G A L + + + N+ F +D G++ L+ + VL +
Sbjct: 1190 ATDADQGTNADLSFTINNANNVP-FVIDD-QGNIRTSGPLNRETVPQYNFLVTVLDNGSP 1247
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
Q NP A V I +LD+ND P + + Y ++ E++ V QV ATD D
Sbjct: 1248 QQAGNP----PATVTINILDVNDEPPVLDRNSYEFTVSEDVNFNTFVGQVTATDPDLSGT 1303
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+T+ DP ++ SG T+R T LD +M V+A +
Sbjct: 1304 LTYTFVPADPDFSYI----SG--TIRTNTQLDANQQQVYQMTVFASD 1344
Score = 42.3 bits (95), Expect = 0.099
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 13/161 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ +RY++ GN +F +D G + ++ + L+ T+ L V+
Sbjct: 2416 VRATDDDAGIFGEVRYQITDGNTDNIFRIDQTTG-----QTGEVFVQGLLETGTYRLVVE 2470
Query: 278 ASQLNNPLKTAQA---RVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDK 333
A + +++A + I + D+ D P F + ++ EN P G + +
Sbjct: 2471 ARDTPGDIPSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRA 2530
Query: 334 -DQGENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDRE 372
+ G+ Y + P F I+ S + V LDRE
Sbjct: 2531 INSDATGQLVYTITGPDSQTFMINQLSAGIQVNGP--LDRE 2569
Score = 40.7 bits (91), Expect = 0.30
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 18/134 (13%)
Query: 774 TIYIE--DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF- 830
TIY+ D ND P F + ++ EN+ G+E+ + TD D Y++
Sbjct: 602 TIYVRITDVNDIAPTFTNLPNITYVFENATFGSELYQ---VITTDEDTFYGGFVTYSISL 658
Query: 831 -------GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG----GLSSEAEL 879
F + E G+++ + SL+ E+ Y +++VARD G LSS A L
Sbjct: 659 VTPSTPGSAPNNYFSIGETDGIIQ-LATSLNYEEIQQYFVTVVARDYGTGDTSLSSTATL 717
Query: 880 IIMIGDENDNKPEF 893
+ + + D P F
Sbjct: 718 TVSVLNIQDTNPVF 731
Score = 40.7 bits (91), Expect = 0.30
Identities = 51/251 (20%), Positives = 99/251 (39%), Gaps = 13/251 (5%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ I A D D G + Y L+ + + F +D G + + ++D D + + T+ L
Sbjct: 751 QTITATDPDSNDGNIITYNLVVSDSQGYFVIDQTTGIITVNSQMDRD--NPVLPATYPLI 808
Query: 276 VQASQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVMATDK 333
V A + ++ + AQ + + ND P F+ + Y+ SI E+ N + + D
Sbjct: 809 VSAVETSSGGVSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDG 868
Query: 334 DQGENGEFTYQLDDPKGA-FSIDPR----SGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D + T L + F + P SG + + LD E + +++ A + +
Sbjct: 869 DLITDSTVTVSLQNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDG 928
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLE---KTTYVFPDKVGTKTENIEYYDEQLMSFVNV 445
+ + P+ N P++ + + D+ GT + D S V
Sbjct: 929 QDIAPLMVTVTDVN-DNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAV 987
Query: 446 EVTLLDANDNN 456
+++ N NN
Sbjct: 988 TYSIISGNINN 998
Score = 39.9 bits (89), Expect = 0.53
Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 11/134 (8%)
Query: 417 TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG 476
T Y+ T Y +S V++TLLD NDN P F S + + + +G
Sbjct: 3954 TIYILATNDATYNGTGPYNVLDNISLKEVKITLLDINDNAPRFT-STVISACIPFDISLG 4012
Query: 477 TVIGKVKAVDPDLGQNGMVLYDL-------QRTSNLTITSPFKINPNTGTVSVAE---SP 526
+ V VD D G N + Y L L + F IN TG + +
Sbjct: 4013 MTVVSVAVVDLDGGTNLGIAYSLNSIQFINSEGERLAAINAFTINSETGQIVTNQRFGEA 4072
Query: 527 ILEGRHALFVEASD 540
L+G + V+A+D
Sbjct: 4073 YLQGYFDIVVQATD 4086
Score = 38.7 bits (86), Expect = 1.2
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 911 NGTAGFTIIE---VKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDS 960
NGT + +++ +K LD++ P F IP +I +G T++ + +DLD
Sbjct: 3966 NGTGPYNVLDNISLKEVKITLLDINDNAPRFTSTVISACIPFDISLGMTVVSVAVVDLDG 4025
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI 1002
G N I Y NS +I + L F IN G ++
Sbjct: 4026 GTNLGIAYSLNSIQFI---NSEGERLAAINAFTINSETGQIV 4064
>UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1781
Score = 140 bits (340), Expect = 2e-31
Identities = 136/470 (28%), Positives = 213/470 (45%), Gaps = 39/470 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+ D NDN PVF S+ + S+ N GT + V A DPD G N V Y S+
Sbjct: 1 VTITVQDVNDNAPVFT-SDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYATYGGSH 59
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I+ ++G + + E + +++ V ASD NPS+ + +VT+
Sbjct: 60 ---GNKFAIDASSGRIYTTGTFDRETKDDYSINVTASDH-GNPSKSSTCVVLVTV----- 110
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGVPF 620
N + P F Y F + + +G S+G + +DA E ++Y ++ E F
Sbjct: 111 -ADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVS--PEKATF 167
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKG 679
++ +G ITV L R Y A LS TV V D ND R V L
Sbjct: 168 SMNPVTGEITVGQRLDR-EGANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFL-- 224
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAEDGT 737
+H +F + S G I + ++ G+ N +R+ + G
Sbjct: 225 SHIGTVFIDENASPGTEI-----ITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGR 279
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ T + LDRE + + V+A ++ GV + VT+ + D NDN PVF + Y +
Sbjct: 280 LRTARNLDRETTPRFTLEVLA-YDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVS 338
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDSLDR 855
E E + ++ A D D G++ Y + +G+E +F ++ENTG + I LDR
Sbjct: 339 EGV---VESNIVTVV-AEDRDIGSDGSVTYCI-TQGREGGLFVINENTGTIG-ITAKLDR 392
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
E K Y L + A D G LSSEA++I+ + D+ND+ P F KV+
Sbjct: 393 ETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQ 442
Score = 134 bits (323), Expect = 2e-29
Identities = 138/468 (29%), Positives = 206/468 (44%), Gaps = 34/468 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV-GTVIGKVKAVDPDLGQNGMV 495
E S+ V +TL D NDNNPVF P Y + N V+ V+A D D V
Sbjct: 717 EPKTSYATVRITLRDVNDNNPVFSPIE-YRCELAENTTPRSVVVCSVRATDRDERGQQSV 775
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLA 553
Y + S F I+ TG + E + F + A D+ +P A
Sbjct: 776 RYSILGGSG---KDKFVIDERTGEIRATVEFDFEVTMSSFLMIAAKDEGLSPQRTADPPA 832
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V I +T G +P F+ + + V N IG SV ++ D + D V Y LL
Sbjct: 833 SVHILIT----GVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKGPDGVVLYHLL 888
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNAT--VHV 666
G + F ++ +G ++V DL + +A Q + S V +AT V V
Sbjct: 889 -GSDNQQGFDLDSNTGTLSVSGDLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTV 947
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQD 725
D ND LK +S HV E G+ IG + TN++++ + ++R+ I+
Sbjct: 948 TDANDPPR-FLKSVYSA---HVTE---GSRIGHVV-TNVTAVDDDSDIRSIRYGISAGNT 999
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ A G + T LDRE YR+TV A N G G + + ++D NDNPP
Sbjct: 1000 GNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATDN-GTPPMTGNATLVVTLDDINDNPP 1058
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTG 844
G + EN GT++ N A D D N F Y++ G F ++ ++G
Sbjct: 1059 HLTPLPCIGRVTENKPQGTQVMTLN---AEDPDLNPNRGPFKYSISGSDYGSFRLNVSSG 1115
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
VV + SLDREK+ Y +S+ D GLS+ +I + D+NDN+P+
Sbjct: 1116 VVSTV-KSLDREKQDAYNISIKVTDARGLSAVNFCMIHVEDQNDNRPK 1162
Score = 107 bits (256), Expect = 3e-21
Identities = 114/415 (27%), Positives = 179/415 (43%), Gaps = 42/415 (10%)
Query: 931 VDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKR 990
+ +G +F I EN GT II L A+D DSG+N +IRY F ++ ++
Sbjct: 224 LSHIGTVF-IDENASPGTEIITLQAVDGDSGVNAEIRYAF----------VTGNS---NN 269
Query: 991 YFVINERHGHVIVARSLPPES--EFRLNISALD-GGNLNDNIS-VRVFVKDVNDHFPVFK 1046
F IN G + AR+L E+ F L + A D G D+++ V V ++DVND+ PVF
Sbjct: 270 SFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFT 329
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ Y V E ++ V A D D G + ++TY I F I+ TG + +
Sbjct: 330 MSEYAAEVSEGVVESNIVTVV-AEDRDIGSDGSVTYCITQGREGGLFVINENTGTIGITA 388
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
+LDRET+ KY L V A D G D ND++P F L K E
Sbjct: 389 KLDRETKSKYTLRVQATDGG-SPALSSEADVIVNVLDQNDHAPVF--TPATLTVKVQE-- 443
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL---ILYSLPQRKN 1223
+ +V+ + + NA + + + N + L +Y+L R
Sbjct: 444 --DTGSGTTVIKVSAVDGDVGSNADVTYSTGMITLNRAIAFKPFSALPNPNIYNLTVR-- 499
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+N+ P + A + + V D D PVFI Y L ++ + V + + +
Sbjct: 500 ARNIYPPHYKADAAIQIEVLDTNDHA-----PVFIKSVYLLFAVQDAGSGVSIGRVEAVD 554
Query: 1284 HYE---NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ N +RY ++ N T F + P G + + S +V TY + VRA
Sbjct: 555 KFDYGPNALVRYEAISGNGTG---RFRVAPETGEVLIASSLRDDVNKTYYIRVRA 606
Score = 105 bits (251), Expect = 1e-20
Identities = 122/468 (26%), Positives = 212/468 (45%), Gaps = 44/468 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP-DLGQNGMVLYDLQRTS 503
+++ +LD ND+ PVF+ S F+++ +A G IG+V+AVD D G N +V Y+ +
Sbjct: 514 IQIEVLDTNDHAPVFIKSVYLLFAVQ-DAGSGVSIGRVEAVDKFDYGPNALVRYEAISGN 572
Query: 504 NLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
T F++ P TG V +A S + + + V ASD P + A V +EVT
Sbjct: 573 G---TGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDM-GQP--KMSDTAGVYVEVTE 626
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN-DVSYDLLHGYEEGVP 619
+ P P F A Y+ ++ +G+++ + D F +N ++SYD++ G +
Sbjct: 627 --RNLHP--PVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQEY- 681
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLL 677
F + +G + V L ++ Y V+ + + ATV + DVND V
Sbjct: 682 FGIGLTNGSLYVSKPLDYEHQENYSLN-VSATDGGKEPKTSYATVRITLRDVNDNNPVF- 739
Query: 678 KGAHSPIIF--HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
SPI + + EN+ ++ + + G +VR+ I +
Sbjct: 740 ----SPIEYRCELAENTTPRSV-VVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERT 794
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVI---SGAGIYQVTIYIEDENDNPPVFEHATY 792
G I D E + +IA ++G+ + V I I N+ PVF + +
Sbjct: 795 GEIRATVEFDFEV-TMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVF 853
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGD 851
+ EN+ IG + + ATD D+G + + +Y L G + ++ FD+D NTG + GD
Sbjct: 854 TATVAENAPIGHSVLR---VSATDKDKGPDGVVLYHLLGSDNQQGFDLDSNTGTLSVSGD 910
Query: 852 SLDREKKIMYKLSLVARD------TGGLSSEAELIIMIGDENDNKPEF 893
LD E+ + L ++A++ T + A +++ + D ND P F
Sbjct: 911 -LDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRF 956
Score = 103 bits (248), Expect = 3e-20
Identities = 100/388 (25%), Positives = 163/388 (42%), Gaps = 27/388 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VT+ D NDN+P F P+ Y F + +A VG IG V A D D+G+N + Y +
Sbjct: 106 VLVTVADNNDNSPKF-PALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPEK 164
Query: 505 LTITSPFKINPNTGTVSVAESPILEG-RHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
T F +NP TG ++V + EG +++ V A+D P + V+ +
Sbjct: 165 AT----FSMNPVTGEITVGQRLDREGANYSIRVTATDLGTPPLSASMEITVIVDDY---- 216
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFA 621
++P +G + + N GT + ++ D+ ++ Y + G F
Sbjct: 217 NDHRPVFLSHIGTVF---IDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNN-SFT 272
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGA 680
+ +G + +L R P + E +A VTN TV + DVND + V
Sbjct: 273 INSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSE 332
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
++ E S G I G+V + I ++ + GTI
Sbjct: 333 YA------AEVSEGVVESNIVTVVAEDRDIGSDGSVTYCITQGREGGLFVINENTGTIGI 386
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
LDRE + Y + V A + G + + V + + D+ND+ PVF AT + E++
Sbjct: 387 TAKLDRETKSKYTLRVQAT-DGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDT 445
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYT 828
GT + + A D D G+NA Y+
Sbjct: 446 GSGTTVIK---VSAVDGDVGSNADVTYS 470
Score = 101 bits (241), Expect = 2e-19
Identities = 116/440 (26%), Positives = 184/440 (41%), Gaps = 37/440 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V V +LD ND+ PVF P+ L ++ + GT + KV AVD D+G N V Y
Sbjct: 412 LSSEADVIVNVLDQNDHAPVFTPATL-TVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYS 470
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
T +T+ P S +P + + L V A + P + A + IE
Sbjct: 471 ---TGMITLNRAIAFKP----FSALPNPNI---YNLTVRARN--IYPPHYKAD-AAIQIE 517
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND---VSYDLLHGYE 615
V P F+ + Y + + G G S+G++ D F+ V Y+ + G
Sbjct: 518 VL----DTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNG 573
Query: 616 EGVPFAVEERSGVITVVDDL-SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
G F V +G + + L N+ Y + +S V V + N
Sbjct: 574 TG-RFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERN---- 628
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRF-LIANQQDVTDDIAI 732
L S ++ EN A+G T ++ G G + + +IA I +
Sbjct: 629 -LHPPVFSKAVYQTSENE-DIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQEYFGIGL 686
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+G+++ KPLD E ++ Y + V A + G V I + D NDN PVF Y
Sbjct: 687 T-NGSLYVSKPLDYEHQENYSLNVSAT-DGGKEPKTSYATVRITLRDVNDNNPVFSPIEY 744
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ EN+ + + ++ATD DE G ++ L G GK+ F +DE TG ++ +
Sbjct: 745 RCELAENTTPRSVVVCS--VRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATVE 802
Query: 852 SLDREKKIMYKLSLVARDTG 871
D E + L + A+D G
Sbjct: 803 -FDFEVTMSSFLMIAAKDEG 821
Score = 97.9 bits (233), Expect = 2e-18
Identities = 128/472 (27%), Positives = 198/472 (41%), Gaps = 53/472 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S NV V L D NDN PVF S Y + S V + I V A D D+G +G V Y +
Sbjct: 310 SVTNVTVVLRDVNDNQPVFTMSE-YAAEV-SEGVVESNIVTVVAEDRDIGSDGSVTYCIT 367
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASD--QPANPSERRYSLAVVT 556
+ + F IN NTGT+ + E ++ L V+A+D PA SE A V
Sbjct: 368 QGREGGL---FVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSE-----ADVI 419
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYD----L 610
+ V P F A V + G GT+V ++ D DV+Y
Sbjct: 420 VNVL----DQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSTGMIT 475
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
L+ PF+ + + P Y +A A+Q + V+D N
Sbjct: 476 LNRAIAFKPFSALPNPNIYNLTVRARNIYPPHYKADA-AIQ------------IEVLDTN 522
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D V +K + ++F V++ +G +IG++ + YG VR+ +
Sbjct: 523 DHAPVFIKSVY--LLFAVQDAGSGVSIGRVEAVDKFD-YG-PNALVRYEAISGNGTGRFR 578
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISG-AGIYQVTIYIEDENDNPPVFE 788
E G + L + Y + V A + + +S AG+Y + + + N +PPVF
Sbjct: 579 VAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVY---VEVTERNLHPPVFS 635
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
A Y+ E+ +G+ + + ATD D G N Y + G +E F + G +
Sbjct: 636 KAVYQTSENEDIAVGSALL---TVTATDRDFGRNGEISYDIIAGNSQEYFGIGLTNGSL- 691
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
++ LD E + Y L++ A D G +S A + I + D NDN P F+ IE
Sbjct: 692 YVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIE 743
Score = 93.1 bits (221), Expect = 5e-17
Identities = 106/409 (25%), Positives = 172/409 (42%), Gaps = 41/409 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+ GTT+I + A D D+G N ++ Y + F I+ G
Sbjct: 24 IAENVDDGTTVITVTATDPDAGDNAKVSYATYGGSH-------------GNKFAIDASSG 70
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + E+ ++ +N++A D GN + + + V V V D ND+ P F Y F++
Sbjct: 71 RIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIA 130
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E +G V A+DAD G+NA LTY I S F ++P+TG ++V LDRE +
Sbjct: 131 EDAAVGASIGTVSASDADIGENARLTYSI-VSPEKATFSMNPVTGEITVGQRLDREGAN- 188
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA-----FDELLEWKHPEADELSN 1170
Y + V A D G D ND+ P F + F + E L
Sbjct: 189 YSIRVTATDLG-TPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQA 247
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ---QNL 1227
+ +S + + A + N+ T+ + T + L + P+ + +L
Sbjct: 248 VDGDSGVNAEIRYAFVTGNSNNSFTINSI----TGRLRTARNLDRETTPRFTLEVLAYDL 303
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN-VNAPVELVSLNLTEHYE 1286
G+P S + V + DV D ++PVF Y E+ E V + + V +
Sbjct: 304 GVPRKDSVTNVTVVLRDVND-----NQPVFTMSEYAAEVSEGVVESNIVTVVAEDRDIGS 358
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + Y I + + FVI+ GT+ + DRE K Y + V+A
Sbjct: 359 DGSVTYCITQGREGGL---FVINENTGTIGITAKLDRETKSKYTLRVQA 404
Score = 92.7 bits (220), Expect = 7e-17
Identities = 102/363 (28%), Positives = 153/363 (42%), Gaps = 46/363 (12%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + V+DVND+ PVF + ++ E + V ATD D G NA ++Y
Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYATYGGSHG 60
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I +G + G DRET+D Y + V A D+G D NDNSPK
Sbjct: 61 NKFAIDASSGRIYTTGTFDRETKDDYSINVTASDHG-NPSKSSTCVVLVTVADNNDNSPK 119
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAK----VFAND--T 1204
F A + + A S+ + A I ENA + ++ F+ + T
Sbjct: 120 FPALHYVFDIAEDAAVG------ASIGTVSASDADIGENARLTYSIVSPEKATFSMNPVT 173
Query: 1205 DFIGNGNGL----ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
I G L YS+ R +LG P LS++ + V V D D +PVF+S
Sbjct: 174 GEITVGQRLDREGANYSI--RVTATDLGTPPLSASMEITVIVDDYNDH-----RPVFLSH 226
Query: 1261 YYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
+ I+EN + E+++L + N ++RY + N + +F I+ G L
Sbjct: 227 IGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNN---SFTINSITGRLRTA 283
Query: 1319 RSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
R+ DRE + + V A Y +P + +T V V ++DVNDN P
Sbjct: 284 RNLDRETTPRFTLEVLA----YDLGVPRK---------DSVT----NVTVVLRDVNDNQP 326
Query: 1379 KFT 1381
FT
Sbjct: 327 VFT 329
Score = 89.0 bits (211), Expect = 9e-16
Identities = 126/492 (25%), Positives = 206/492 (41%), Gaps = 45/492 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V VEVT + N + PVF + +Y+ S + VG+ + V A D D G+NG + YD+
Sbjct: 620 VYVEVT--ERNLHPPVFSKA-VYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAG 676
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
++ F I G++ V++ E + ++L V A+D P + S A V I +
Sbjct: 677 NS---QEYFGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEP---KTSYATVRITL- 729
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSN-VGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEG 617
R N P F Y + N V +R D E Q V Y +L G +
Sbjct: 730 RDVNDNN---PVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKD 786
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE---NANLSIVTNATVHVV--DVNDE 672
F ++ER+G I + + M F +A ++ + + A+VH++ VN+
Sbjct: 787 -KFVIDERTGEIRATVEFD-FEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEF 844
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
V ++ + V EN A IG + + + G V + + +
Sbjct: 845 LPVFVQSVFTAT---VAEN---APIGHSVLRVSATDKDKGPDGVVLYHLLGSDNQQGFDL 898
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVI-SGAGIYQVTIYIEDENDNPPVFE 788
+ GT+ LD E+ + + VIA+ F V S + + + D ND PP F
Sbjct: 899 DSNTGTLSVSGDLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFL 957
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y + E S+IG + + A D D ++ G F +D TG V+
Sbjct: 958 KSVYSAHVTEGSRIGHVV---TNVTAVDDDSDIRSIRYGISAGNTGNAFVMDAVTGFVRT 1014
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ LDRE Y+L++ A D G ++ A L++ + D NDN P + +V
Sbjct: 1015 AAE-LDREAIAEYRLTVTATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRV---T 1070
Query: 907 ETKLNGTAGFTI 918
E K GT T+
Sbjct: 1071 ENKPQGTQVMTL 1082
Score = 86.6 bits (205), Expect = 5e-15
Identities = 55/181 (30%), Positives = 89/181 (49%), Gaps = 10/181 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D GV A +RY ++GN F+++S+ G L + LD + F L+V
Sbjct: 245 LQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGRLRTARNLDRETTPR-----FTLEVL 299
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A L P K + V + L D+NDN P F + Y + E + +++ V+A D+D G
Sbjct: 300 AYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGVVES-NIVTVVAEDRDIGS 358
Query: 338 NGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
+G TY + + G F I+ +G T+ LDRE S ++V A + + + A
Sbjct: 359 DGSVTYCITQGREGGLFVINENTG--TIGITAKLDRETKSKYTLRVQATDGGSPALSSEA 416
Query: 396 D 396
D
Sbjct: 417 D 417
Score = 85.4 bits (202), Expect = 1e-14
Identities = 128/477 (26%), Positives = 201/477 (42%), Gaps = 49/477 (10%)
Query: 444 NVEVTLL--DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
++E+T++ D ND+ PVF+ S++ + NA GT I ++AVD D G N + Y
Sbjct: 206 SMEITVIVDDYNDHRPVFL-SHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFV- 263
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEV 559
T N + F IN TG + A + E R L V A D R+ S+ VT+ V
Sbjct: 264 TGNSN--NSFTINSITGRLRTARNLDRETTPRFTLEVLAYDLGV---PRKDSVTNVTV-V 317
Query: 560 TRGTKGNKP--DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
R N+P + ++ E V SN I T V + R D V+Y + G E G
Sbjct: 318 LRDVNDNQPVFTMSEYAAEVSEGVVESN--IVTVVAEDR--DIGSDGSVTYCITQGREGG 373
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
+ F + E +G I + L R + Y A + LS + V+V+D ND V
Sbjct: 374 L-FVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVF 432
Query: 677 LKGAHSPIIFHVK-ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+P VK + G+ I +S++ G+ + + DVT +
Sbjct: 433 -----TPATLTVKVQEDTGSGTTVI---KVSAVDGD--------VGSNADVTYSTGMITL 476
Query: 736 GTIFTQKPLDR-EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
KP ++Y +TV A N + I + D ND+ PVF + Y
Sbjct: 477 NRAIAFKPFSALPNPNIYNLTVRAR-NIYPPHYKADAAIQIEVLDTNDHAPVFIKSVYLL 535
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMY-TLFGEGKEMFDVDENTGVVKFIGDSL 853
F ++++ G+ + + + D G NAL Y + G G F V TG V I SL
Sbjct: 536 FAVQDA--GSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGEV-LIASSL 592
Query: 854 DREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN----QIEENSKVRI 904
+ Y + + A D G +S A + + + + N + P F+ Q EN + +
Sbjct: 593 RDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAV 649
Score = 82.2 bits (194), Expect = 1e-13
Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 10/171 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y++I+GN ++ F + NGSL++ K LD + + N + L V
Sbjct: 656 VTATDRDFGRNGEISYDIIAGNSQEYFGIGLTNGSLYVSKPLDYEHQEN-----YSLNVS 710
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQG 336
A+ KT+ A V I L D+NDN P F Y + EN P V V ATD+D+
Sbjct: 711 ATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDER 770
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y + K F ID R+G +R D E S + + AK+
Sbjct: 771 GQQSVRYSILGGSGKDKFVIDERTG--EIRATVEFDFEVTMSSFLMIAAKD 819
Score = 81.4 bits (192), Expect = 2e-13
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 9/173 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y G+ F++D+ +G ++ D + + + N V
Sbjct: 37 VTATDPDAGDNAKVSYATYGGSHGNKFAIDASSGRIYTTGTFDRETKDDYSIN-----VT 91
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS NP K++ V + + D NDN P+F Y I E+ G S+ V A+D D GE
Sbjct: 92 ASDHGNPSKSSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGE 151
Query: 338 NGEFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKETNP 388
N TY + P K FS++P +G +TV + LDRE A+ S+R+ T P
Sbjct: 152 NARLTYSIVSPEKATFSMNPVTGEITVGQR--LDREGANYSIRVTATDLGTPP 202
Score = 79.0 bits (186), Expect = 9e-13
Identities = 116/514 (22%), Positives = 198/514 (38%), Gaps = 58/514 (11%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
+ K++ TAG +EV +N + E+I +G+ ++ + A D D G NG+I
Sbjct: 611 QPKMSDTAG-VYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEI 669
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN 1024
Y+ ++ ++ E YF I +G + V++ L E + + LN+SA DGG
Sbjct: 670 SYDI----------IAGNSQE---YFGIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGK 716
Query: 1025 --LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR-VLGKVDATDADFGQNANLT 1081
+VR+ ++DVND+ PVF Y + E R V+ V ATD D ++
Sbjct: 717 EPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVR 776
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX--XXXXX 1139
Y I F I TG + E D E L + A+D G
Sbjct: 777 YSILGGSGKDKFVIDERTGEIRATVEFDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHI 836
Query: 1140 XXXDVNDNSPKFY--AFDELLEWKHPEADEL-------SNHNFESVMMIPVYKATIEENA 1190
VN+ P F F + P + + + V++ + + ++
Sbjct: 837 LITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDKGPDGVVLYHLLGSDNQQGF 896
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
+ + + + D G++ + + QN PS + A ++VTV D
Sbjct: 897 DLDSNTGTLSVSG-DLDNERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDA----- 950
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
+D P F+ Y + E + ++ + + + Y ++ +T FV+D
Sbjct: 951 -NDPPRFLKSVYSAHVTEGSRIGHVVTNVTAVDDDSDIRSIRYGISAGNTG--NAFVMDA 1007
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRI 1370
G + DRE Y + V A ++ MT + +VV +
Sbjct: 1008 VTGFVRTAAELDREAIAEYRLTVTA----------------TDNGTPPMTG-NATLVVTL 1050
Query: 1371 KDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
D+NDN P T P + + P G QVM L
Sbjct: 1051 DDINDNPPHLT--PLPCIGRVTENKPQGTQVMTL 1082
Score = 77.8 bits (183), Expect = 2e-12
Identities = 65/237 (27%), Positives = 103/237 (43%), Gaps = 18/237 (7%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++ V N + L +F I E+ +G +I ++A D D G N ++ Y +
Sbjct: 107 LVTVADNNDNSPKFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSI-----VS 161
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE-SEFRLNISALDGGN--LNDNISVRVF 1034
P K + F +N G + V + L E + + + ++A D G L+ ++ + V
Sbjct: 162 PEKAT---------FSMNPVTGEITVGQRLDREGANYSIRVTATDLGTPPLSASMEITVI 212
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V D NDH PVF ++E + + A D D G NA + Y +++ F
Sbjct: 213 VDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFT 272
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I+ +TG L LDRET ++ L V+A D G DVNDN P F
Sbjct: 273 INSITGRLRTARNLDRETTPRFTLEVLAYDLG-VPRKDSVTNVTVVLRDVNDNQPVF 328
Score = 77.0 bits (181), Expect = 4e-12
Identities = 51/171 (29%), Positives = 86/171 (50%), Gaps = 10/171 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D ++RY ++ G+ + F +D G + E D + + ++F++
Sbjct: 762 VRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATVEFDFE----VTMSSFLMIAA 817
Query: 278 ASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ +P +TA A V I + +N+ LP F + ++ EN P G SVL+V ATDKD+
Sbjct: 818 KDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSATDKDK 877
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
G +G Y L D + F +D +G L+V LD E + ++V AK
Sbjct: 878 GPDGVVLYHLLGSDNQQGFDLDSNTGTLSVSGD--LDNERAGIVTLRVIAK 926
Score = 72.5 bits (170), Expect = 8e-11
Identities = 77/315 (24%), Positives = 137/315 (43%), Gaps = 21/315 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL--TI 130
G +S+ V V + D ND+ P+F TP +TV TG + ++ + +
Sbjct: 408 GSPALSSEADVIVNVLDQNDHAPVF--TPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNA 465
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGND--DGHFALESSHKPVLLLRKVL 188
+T G+ AF + PN +++ V + H+ +++ + +VL
Sbjct: 466 DVTYSTGMITLNRAIAF-KPFSALPNPNIYNLTVRARNIYPPHYKADAA-----IQIEVL 519
Query: 189 DYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRKLFSL 246
D + F + V + + + + A+D+ D G A +RYE ISGN F +
Sbjct: 520 DTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRV 579
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G + + L D T+ ++V+AS + P + A V +E+ + N + P F
Sbjct: 580 APETGEVLIASSLRDDVN-----KTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVF 634
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVR 364
Y S E++ G ++L V ATD+D G NGE +Y + + + F I +G L V
Sbjct: 635 SKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQEYFGIGLTNGSLYVS 694
Query: 365 NQTVLDREAHSSLRM 379
+ + + SL +
Sbjct: 695 KPLDYEHQENYSLNV 709
Score = 71.7 bits (168), Expect = 1e-10
Identities = 66/210 (31%), Positives = 93/210 (44%), Gaps = 19/210 (9%)
Query: 947 GTTIIKLNALD-LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
G +I ++ A+D D G N +RYE +S + R+ V E G V++A
Sbjct: 544 GVSIGRVEAVDKFDYGPNALVRYE----------AISGNG--TGRFRVAPET-GEVLIAS 590
Query: 1006 SLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
SL + + + + A D G ++D V V V + N H PVF K Y + E
Sbjct: 591 SLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVG 650
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
L V ATD DFG+N ++Y I ++ F I G L V+ LD E ++ Y L V
Sbjct: 651 SALLTVTATDRDFGRNGEISYDIIAGNSQEYFGIGLTNGSLYVSKPLDYEHQENYSLNVS 710
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
A D G DVNDN+P F
Sbjct: 711 ATDGG-KEPKTSYATVRITLRDVNDNNPVF 739
Score = 70.5 bits (165), Expect = 3e-10
Identities = 69/282 (24%), Positives = 125/282 (44%), Gaps = 22/282 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTI 130
G +SA + +TV ++D ND+ P+FL V +DE G + + G + I
Sbjct: 199 GTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEI 258
Query: 131 PLTVPRGLT--------IFKDIR-AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
G + I +R A + D+ TP + V D G +S
Sbjct: 259 RYAFVTGNSNNSFTINSITGRLRTARNLDRETTPRFTLE---VLAYDLGVPRKDSVTNVT 315
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
++LR V D + S + I+ + A D+D+G ++ Y + G +
Sbjct: 316 VVLRDVNDNQPVFTMSEYAAEVSEGVVESNIV---TVVAEDRDIGSDGSVTYCITQGREG 372
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
LF ++ G++ + +LD + + + + L+VQA+ +P +++A V + +LD ND
Sbjct: 373 GLFVINENTGTIGITAKLDRETK-----SKYTLRVQATDGGSPALSSEADVIVNVLDQND 427
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ P F + + E+ +G +V++V A D D G N + TY
Sbjct: 428 HAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTY 469
Score = 66.1 bits (154), Expect = 7e-09
Identities = 85/323 (26%), Positives = 138/323 (42%), Gaps = 45/323 (13%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHV----------TVDELTPT----GEKAFIFLIAPIGPSL 128
VT+ ++DVNDN P+F + V TV +T T G+ A + A G S
Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSY-ATYGGSH 59
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKV 187
+ FDR+ + YSI V+ +D G+ S ++L V
Sbjct: 60 GNKFAIDASSGRIYTTGTFDRETKDD------YSINVTASDHGN---PSKSSTCVVLVTV 110
Query: 188 LDYDAGDKEFQLVI----MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
D + +F + +A + I + A D D+G A L Y ++S ++
Sbjct: 111 ADNNDNSPKFPALHYVFDIAEDAAVGASI---GTVSASDADIGENARLTYSIVSP-EKAT 166
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS++ V G + + + LD + AN + ++V A+ L P +A + + + D ND+
Sbjct: 167 FSMNPVTGEITVGQRLDREG-----AN-YSIRVTATDLGTPPLSASMEITVIVDDYNDHR 220
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P F + I EN G ++ + A D D G N E Y + +F+I+ +G L
Sbjct: 221 PVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGRL 280
Query: 362 -TVRNQTVLDREAHSSLRMKVYA 383
T RN LDRE ++V A
Sbjct: 281 RTARN---LDRETTPRFTLEVLA 300
Score = 60.5 bits (140), Expect = 3e-07
Identities = 99/421 (23%), Positives = 175/421 (41%), Gaps = 57/421 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ GTT+IK++A+D D G N + Y S + + R
Sbjct: 441 VQEDTGSGTTVIKVSAVDGDVGSNADVTY-------------STGMITLNRAIAFKP--- 484
Query: 1000 HVIVARSLPPESEFRLNISALD--GGNLNDNISVRVFVKDVNDHFPVFKKTWY-NFNVEE 1056
+LP + + L + A + + + ++++ V D NDH PVF K+ Y F V++
Sbjct: 485 ----FSALPNPNIYNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFIKSVYLLFAVQD 540
Query: 1057 AQYTRRVLGKVDATDA-DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
A + +G+V+A D D+G NA + Y + F ++P TG + + L +
Sbjct: 541 AG-SGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPETGEVLIASSLRDDVNKT 599
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y + V A D G + N + P F ++ E ++++ + +
Sbjct: 600 YYIRVRASDMG-QPKMSDTAGVYVEVTERNLHPPVF----SKAVYQTSENEDIAVGS--A 652
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG--NGLILYSLP-QRKNQQNL----- 1227
++ + N I + + N ++ G G NG + S P ++Q+N
Sbjct: 653 LLTVTATDRDFGRNGEISYDI--IAGNSQEYFGIGLTNGSLYVSKPLDYEHQENYSLNVS 710
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN-APVELVSLNLT 1282
G +S A + +T+ DV D + PVF Y E+ EN V + S+ T
Sbjct: 711 ATDGGKEPKTSYATVRITLRDVND-----NNPVFSPIEYRCELAENTTPRSVVVCSVRAT 765
Query: 1283 EHYENFK--MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ E + +RY IL + D FVID R G + D EV + +++ A+ +
Sbjct: 766 DRDERGQQSVRYSILGGSGKD---KFVIDERTGEIRATVEFDFEVTMSSFLMIAAKDEGL 822
Query: 1341 S 1341
S
Sbjct: 823 S 823
Score = 60.1 bits (139), Expect = 5e-07
Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D + ++RY + +GN F +D+V G + ELD +A + L V
Sbjct: 978 VTAVDDDSDI-RSIRYGISAGNTGNAFVMDAVTGFVRTAAELDREA-----IAEYRLTVT 1031
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P T A + + L D+NDN P + EN P G V+ + A D D
Sbjct: 1032 ATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLNP 1091
Query: 338 N-GEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
N G F Y + G+F ++ SG V LDRE + + +
Sbjct: 1092 NRGPFKYSISGSDYGSFRLNVSSG--VVSTVKSLDREKQDAYNISI 1135
Score = 58.4 bits (135), Expect = 1e-06
Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 5/105 (4%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPK 349
V I + D+NDN P F D + +SI EN+ +G +V+ V ATD D G+N + +Y
Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYATYGGSHG 60
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
F+ID SG + DRE + V A + NPS T
Sbjct: 61 NKFAIDASSG--RIYTTGTFDRETKDDYSINVTASDHGNPSKSST 103
Score = 48.8 bits (111), Expect = 0.001
Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 9/164 (5%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
FV++ G V A L E+ E+RL ++A D G + N ++ V + D+ND+ P
Sbjct: 1003 FVMDAVTGFVRTAAELDREAIAEYRLTVTATDNGTPPMTGNATLVVTLDDINDNPPHLTP 1062
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLPFEISPLTGVLSVNG 1106
V E + + ++A D D N Y I SD F ++ +GV+S
Sbjct: 1063 LPCIGRVTENKPQGTQVMTLNAEDPDLNPNRGPFKYSISGSDYG-SFRLNVSSGVVSTVK 1121
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
LDRE +D Y +++ D D NDN PK
Sbjct: 1122 SLDREKQDAYNISIKVTD---ARGLSAVNFCMIHVEDQNDNRPK 1162
Score = 36.7 bits (81), Expect = 4.9
Identities = 16/42 (38%), Positives = 28/42 (66%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
A+D+DIG NA + Y I++ + F+++PV+G + V L R+
Sbjct: 144 ASDADIGENARLTYSIVSPEKATFSMNPVTGEITVGQRLDRE 185
>UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 470
Score = 140 bits (340), Expect = 2e-31
Identities = 133/460 (28%), Positives = 204/460 (44%), Gaps = 34/460 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + +F+ ++V + D ND PVF P N Y ++ + V + +V AVD D G N V
Sbjct: 32 DGKFQAFLEIDVHIQDINDQYPVFSPQN-YSVAISEESWVRLPVLQVTAVDMDSGSNSQV 90
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
Y + + S F I+PNTG + V + E + L V+A D P+ A
Sbjct: 91 TYSI-----VDGNSSFSIDPNTGQIIVHRTLDFEVTRSFILRVQARDN-GKPALVSRDYA 144
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
VTI +T N P F Y F + +V GT G +R NDA + +SY +
Sbjct: 145 YVTINITDENDNN----PVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSI- 199
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVN 670
+ FAV+E +G ++VV D+ R +Y F V ++ + +V V DVN
Sbjct: 200 PDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVN 259
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + ++ I + S G I + H + I N N++ + D
Sbjct: 260 DNQPIFRPQNYTVRIS--EGTSVGTKIVWV-HAHDEDIGPNALITYHIDSGNKESIFD-- 314
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFN-KGVISGAGIYQVTIYIEDENDNPPVFEH 789
EDGTI LDRE D Y + ++A N + V I IED NDN P F
Sbjct: 315 --IEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA 372
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGV 845
+ Y I E++ IGT++ + A+D D G+NA Y + K +FDV++ TG
Sbjct: 373 SVYSVNISEDTSIGTQVLS---VYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGA 429
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
+ + ++ + ARD G L S+ + IM+
Sbjct: 430 ISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEIMV 469
Score = 109 bits (261), Expect = 8e-22
Identities = 107/403 (26%), Positives = 175/403 (43%), Gaps = 45/403 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E + ++++ A+D+DSG N Q+ Y ++ F I+ G
Sbjct: 64 ISEESWVRLPVLQVTAVDMDSGSNSQVTYSI---------------VDGNSSFSIDPNTG 108
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN----LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+IV R+L E F L + A D G D V + + D ND+ PVF K YNF+
Sbjct: 109 QIIVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFS 168
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ E V G V A DAD G+NA L+Y I D F + +TG LSV G++DRE
Sbjct: 169 ITEDVAKGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERT 228
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y VV D+G DVNDN P F + + + E +
Sbjct: 229 GIYSFVVVVTDHG-SSPRVGFAVVSVQVKDVNDNQPIFRPQNYTV--RISEGTSVGT--- 282
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR-KNQQNLGL--- 1229
++ + + I NA I + I +G ++ +L + +Q LG+
Sbjct: 283 -KIVWVHAHDEDIGPNALITYHIDSGNKESIFDIEDGTIVLNGTLDREVMDQYTLGILAT 341
Query: 1230 -----PSLS-STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
P LS AI+++T+ D+ D + P F + Y + I E+ + +++S+ ++
Sbjct: 342 DNGEPPQLSRDPAIVVITIEDIND-----NYPEFNASVYSVNISEDTSIGTQVLSVYASD 396
Query: 1284 H--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
N ++Y+I+ + DI+R F ++ G + + D E
Sbjct: 397 KDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFE 439
Score = 93.9 bits (223), Expect = 3e-17
Identities = 85/306 (27%), Positives = 142/306 (46%), Gaps = 27/306 (8%)
Query: 599 DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
D+ + V+Y ++ G F+++ +G I V L + V ++N ++
Sbjct: 83 DSGSNSQVTYSIVDGNSS---FSIDPNTGQIIVHRTLD-FEVTRSFILRVQARDNGKPAL 138
Query: 659 VTN----ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
V+ T+++ D ND V K +++ F + E+ A + N + N
Sbjct: 139 VSRDYAYVTINITDENDNNPVFDKRSYN---FSITEDVAKGTVFGFVRANDADSGKNA-- 193
Query: 715 NVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ + I ++ DV A+ E G + +DRE+ +Y V+ + G G V
Sbjct: 194 KLSYSIPDE-DVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVT-DHGSSPRVGFAVV 251
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
++ ++D NDN P+F Y I E + +GT+I + A D D G NAL Y +
Sbjct: 252 SVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVW---VHAHDEDIGPNALITYHIDSGN 308
Query: 834 KE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSE-AELIIMIGDEND 888
KE +FD+++ T V + +LDRE Y L ++A D G LS + A ++I I D ND
Sbjct: 309 KESIFDIEDGTIV---LNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDIND 365
Query: 889 NKPEFN 894
N PEFN
Sbjct: 366 NYPEFN 371
Score = 92.7 bits (220), Expect = 7e-17
Identities = 92/388 (23%), Positives = 167/388 (43%), Gaps = 27/388 (6%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISAL-DGGNLNDNISVRVFVKDVNDHFPVFKKTWY 1050
F +N+ G + V RSL ES +++ + G + + V ++D+ND +PVF Y
Sbjct: 1 FAVNKTTGDIKVTRSLDRESNASYSVTVMASDGKFQAFLEIDVHIQDINDQYPVFSPQNY 60
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+ + E + R + +V A D D G N+ +TY I D + F I P TG + V+ LD
Sbjct: 61 SVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSI--VDGNSSFSIDPNTGQIIVHRTLDF 118
Query: 1111 ETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
E +IL V ARDNG D NDN+P F + + ++++
Sbjct: 119 EVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVF----DKRSYNFSITEDVA 174
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
+ A +NA + ++ T + G + S+ +++ G+
Sbjct: 175 KGTVFG--FVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNL--SVVGDIDRERTGI 230
Query: 1230 PSL-------SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
S S+ + V V + ++P+F + Y + I E + ++V ++
Sbjct: 231 YSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVH-- 288
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA----ERQ 1338
H E+ I D+ + + + D +GT+ L + DREV D Y + + A E
Sbjct: 289 AHDEDIGPNALITYHIDSGNKES-IFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPP 347
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKV 1366
+ SR+ P ++ ED+ + +++ V
Sbjct: 348 QLSRD-PAIVVITIEDINDNYPEFNASV 374
Score = 84.6 bits (200), Expect = 2e-14
Identities = 79/280 (28%), Positives = 117/280 (41%), Gaps = 48/280 (17%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F I E++ GT + A D DSG N ++ Y E +V++ F ++E
Sbjct: 167 FSITEDVAKGTVFGFVRANDADSGKNAKLSYSIPDE-------------DVRKTFAVDEI 213
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNF 1052
G++ V + E + + D G+ + + V V VKDVND+ P+F+ Y
Sbjct: 214 TGNLSVVGDIDRERTGIYSFVVVVTDHGS-SPRVGFAVVSVQVKDVNDNQPIFRPQNYTV 272
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E + V A D D G NA +TY I + + F+I G + +NG LDRE
Sbjct: 273 RISEGTSVGTKIVWVHAHDEDIGPNALITYHIDSGNKESIFDIE--DGTIVLNGTLDREV 330
Query: 1113 EDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
D+Y L ++A DNG D+NDN P+F A
Sbjct: 331 MDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA------------------ 372
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
VY I E+ IGT V V+A+D D N +
Sbjct: 373 --------SVYSVNISEDTSIGTQVLSVYASDKDLGSNAH 404
Score = 78.2 bits (184), Expect = 2e-12
Identities = 54/176 (30%), Positives = 90/176 (51%), Gaps = 17/176 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D+D+G A + Y + SGN +F ++ +G++ L LD + + + L +
Sbjct: 287 VHAHDEDIGPNALITYHIDSGNKESIFDIE--DGTIVLNGTLDREV-----MDQYTLGIL 339
Query: 278 ASQLNNP--LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A+ P L A V I + D+NDN PEF Y+++I E+ G VL V A+DKD
Sbjct: 340 ATDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDL 399
Query: 336 GENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKE 385
G N Y + DD K F ++ +G ++ + LD E A++ + +V A++
Sbjct: 400 GSNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSN--LDFESANNRFQFQVEARD 453
Score = 77.8 bits (183), Expect = 2e-12
Identities = 50/159 (31%), Positives = 81/159 (50%), Gaps = 13/159 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D G + + Y ++ GN FS+D G + + + LD + +F+L+VQ
Sbjct: 77 VTAVDMDSGSNSQVTYSIVDGNSS--FSIDPNTGQIIVHRTLDFEV-----TRSFILRVQ 129
Query: 278 ASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A P ++ A V I + D NDN P F+ YN SI E++ G V A D D
Sbjct: 130 ARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADS 189
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
G+N + +Y + +D + F++D +G L+V +DRE
Sbjct: 190 GKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGD--IDRE 226
Score = 72.9 bits (171), Expect = 6e-11
Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 13/171 (7%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I + LDRE Y +TV+A K ++ ++I+D ND PVF Y
Sbjct: 8 GDIKVTRSLDRESNASYSVTVMASDGKF----QAFLEIDVHIQDINDQYPVFSPQNYSVA 63
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I E S + + + A D D G+N+ Y++ +G F +D NTG + + +LD
Sbjct: 64 ISEESWVRLPVLQ---VTAVDMDSGSNSQVTYSIV-DGNSSFSIDPNTGQI-IVHRTLDF 118
Query: 856 EKKIMYKLSLVARDTG--GLSSE--AELIIMIGDENDNKPEFNQIEENSKV 902
E + L + ARD G L S A + I I DENDN P F++ N +
Sbjct: 119 EVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSI 169
Score = 72.1 bits (169), Expect = 1e-10
Identities = 79/331 (23%), Positives = 135/331 (40%), Gaps = 27/331 (8%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
V + A + A+L + V+I+D+ND P+F Y V + E + +
Sbjct: 26 VTVMASDGKFQAFLEIDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSG 85
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-----------VSGNDDGHFALES 176
+T +I +F D PNT VH ++ V D+G AL S
Sbjct: 86 SNSQVTY----SIVDGNSSFSID-PNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVS 140
Query: 177 SHKPVLLLRKVLDYDAGDKEF--QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE 234
+ + + D + + F + + + + K +F + A D D G A L Y
Sbjct: 141 RDYAYVTIN-ITDENDNNPVFDKRSYNFSITEDVAKGTVFGF-VRANDADSGKNAKLSYS 198
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ + RK F++D + G+L + ++D + + + V + + + A V +
Sbjct: 199 IPDEDVRKTFAVDEITGNLSVVGDIDRE-----RTGIYSFVVVVTDHGSSPRVGFAVVSV 253
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
++ D+NDN P F Y + I E G ++ V A D+D G N TY +D
Sbjct: 254 QVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHIDSGNKESIF 313
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G + V N T LDRE + + A +
Sbjct: 314 DIEDGTI-VLNGT-LDREVMDQYTLGILATD 342
Score = 70.5 bits (165), Expect = 3e-10
Identities = 64/229 (27%), Positives = 104/229 (45%), Gaps = 37/229 (16%)
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIR 967
GF ++ V+ K DV+ P+F I E +GT I+ ++A D D G N I
Sbjct: 247 GFAVVSVQVK-----DVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALIT 301
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN- 1024
Y +S + + + G +++ +L E ++ L I A D G
Sbjct: 302 YHIDSG---------------NKESIFDIEDGTIVLNGTLDREVMDQYTLGILATDNGEP 346
Query: 1025 ---LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
D V + ++D+ND++P F + Y+ N+ E + V A+D D G NA++
Sbjct: 347 PQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQ 406
Query: 1082 YFIQPS---DTDLPFEISPLTGVLSVNGELDRET-EDKYILTVVARDNG 1126
YFI S D F+++ TG +S LD E+ +++ V ARDNG
Sbjct: 407 YFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNG 455
Score = 64.9 bits (151), Expect = 2e-08
Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
+++ + D+ND P F Y+++I E VLQV A D D G N + TY + D +
Sbjct: 41 IDVHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVDGNSS 100
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVV 391
FSIDP +G + V LD E S ++V A++ P++V
Sbjct: 101 FSIDPNTGQIIVHR--TLDFEVTRSFILRVQARDNGKPALV 139
Score = 57.6 bits (133), Expect = 2e-06
Identities = 64/227 (28%), Positives = 108/227 (47%), Gaps = 25/227 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA---PIGPSLTIPLTVPRG-- 137
V+V ++DVNDN PIF Y V + E T G K +++ A IGP+ I + G
Sbjct: 251 VSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTK-IVWVHAHDEDIGPNALITYHIDSGNK 309
Query: 138 LTIFKDIRAFDRDKPNTPNSDV--HYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
+IF DI T + +V Y++ + D+G + S P +++ + D +
Sbjct: 310 ESIF-DIEDGTIVLNGTLDREVMDQYTLGILATDNGE-PPQLSRDPAIVVITIEDINDNY 367
Query: 195 KEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI-SGND--RKLFSLD 247
EF V ++ I ++L ++A D+DLG A ++Y +I S ND +++F ++
Sbjct: 368 PEFNASVYSVNISEDTSIGTQVL---SVYASDKDLGSNAHVQYFIIASANDDIKRVFDVN 424
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
G++ LD ++ + N F QV+A P +Q VEI
Sbjct: 425 KTTGAISTTSNLDFESAN----NRFQFQVEARDNGKPALYSQTTVEI 467
Score = 57.2 bits (132), Expect = 3e-06
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+ D NDN P F S +Y ++ + +GT + V A D DLG N V Y + ++N
Sbjct: 356 VVITIEDINDNYPEFNAS-VYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASAN 414
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
I F +N TG +S + E + F + N YS V I VT
Sbjct: 415 DDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALYSQTTVEIMVT 470
Score = 36.3 bits (80), Expect = 6.5
Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 1440 QATDSDIGINADIRYQILNEQAPR-FAIDPVSGTVRVVAALARDAGRVFGF 1489
+A D+D G NA + Y I +E + FA+D ++G + VV + R+ ++ F
Sbjct: 183 RANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSF 233
>UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to
Protocadherin-like wing polarity protein stan precursor
(Protein starry night) (Protein flamingo); n=2;
Apocrita|Rep: PREDICTED: similar to Protocadherin-like
wing polarity protein stan precursor (Protein starry
night) (Protein flamingo) - Apis mellifera
Length = 3166
Score = 140 bits (339), Expect = 3e-31
Identities = 234/964 (24%), Positives = 388/964 (40%), Gaps = 138/964 (14%)
Query: 455 NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKIN 514
N + +LY ++ + G + V+A DP+ G V Y + + + ++
Sbjct: 256 NQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPE---GGTVRYSMSSLLDARSQALLVLD 312
Query: 515 PNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
P TG V+ E H V A D P +L V ++ P
Sbjct: 313 PVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLDTN-------DHAPS 365
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLH--------GYEEGVPFAV 622
F E + V +G++V ++ D A +V Y +L E+ + F +
Sbjct: 366 FEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRI 425
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENA---NLSIVTNAT--VHVVDVNDERGVLL 677
+ R+GV+T L R +Y +++ + A + NAT V V+D ND
Sbjct: 426 DPRTGVVTTRTPLDREKTEVYTV-ILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFT 484
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ +S I + +A I +I T+ S GN VR+ I + G
Sbjct: 485 ERTYSAWIPEDLDYTANPVIARIRATDADS--GNNAA-VRYAIIGGNTQNTFSIDSMVGD 541
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ KPLD E Y++ + A+ + G + + Q+ +++ D NDN P F + ++ +
Sbjct: 542 VALVKPLDYESTRSYKIVIRAQ-DGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVS 600
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN +G I I+A DADEG NA YT+ G F G S +
Sbjct: 601 ENVPVGYSILR---IQAYDADEGANAQIKYTI--------------GARDFTGASTEN-- 641
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
+ ++ V +TG L + +L E ++ +F I +S I + + T T
Sbjct: 642 ---FPIT-VNTETGWLYTTKQL----DREQCSRYQFTVIAADSG-EISKSA--SATVILT 690
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+ +V + + D ++ E+ P GT + + A D D + +I YE
Sbjct: 691 VTDVNDNDPY---FDPKNYESVVSEDDPPGTPVTSVTATDPDE--DARIHYEIT------ 739
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLP----PESEFRLNISALDGGNLNDNISVRV 1033
A + F I ++G ++ + P E F L ++A D G D V V
Sbjct: 740 -------AGNTRGRFAIASQNGRGLITIAQPLDYKQEKRFVLTVTASDSGGRTDTALVYV 792
Query: 1034 FVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-- 1090
+ D N+ PVF+ Y+ +V E+A VL V ATD+D G+NA +TY + + D
Sbjct: 793 NISDANNFSPVFENAPYSVSVFEDAPIGTTVL-VVSATDSDVGKNAQVTYSLDTDNGDQT 851
Query: 1091 -LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F I+P TG ++ LDRE Y+LTV ARD G DVNDN+P
Sbjct: 852 ASEFIINPQTGAITTTKPLDREIVPAYLLTVTARDGG-IPPLSDTTDVEISVTDVNDNAP 910
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
F A P Y+ +I E+ +GT+V +V A D D +
Sbjct: 911 VFEA--------------------------PQYQGSIPEDVLVGTSVLRVSATDAD--TD 942
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE--VEMSDKPVFISR-YYELEI 1266
NG + Y+L G ++ ST ++ T + E + K V + R L
Sbjct: 943 LNGRVRYAL----EDDGDGAFAVDSTTGIIRTAKPLDRESVAKYILKAVAMDRGSPSLST 998
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSP--D 1322
V +E V+ + +EN K+ YI + + + + DP G +V+
Sbjct: 999 VVPVTIKIEDVN-DSPPAFENDKIILYIAENSPIGSTVGEIYAHDPDEGPNAVVQYSVIG 1057
Query: 1323 REVKDTYEVIVR--AER------QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
E +++ + +R A+R ++ E P + + + D V + + DVN
Sbjct: 1058 GEDSNSFALNIRPGADRAELITLEELDYESPKKKFELVVRAASPPLRSDALVQILVTDVN 1117
Query: 1375 DNSP 1378
DN+P
Sbjct: 1118 DNAP 1121
Score = 139 bits (336), Expect = 6e-31
Identities = 178/668 (26%), Positives = 270/668 (40%), Gaps = 73/668 (10%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL---QRTSNLTI 507
D NDN P F S+ E S+ N VG I +++A D D G N + Y + T T
Sbjct: 582 DVNDNAPRFYTSHFQE-SVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTE 640
Query: 508 TSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
P +N TG + + E R+ V A+D S+ + ++T+ T
Sbjct: 641 NFPITVNTETGWLYTTKQLDREQCSRYQFTVIAADS-GEISKSASATVILTV-----TDV 694
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG-VPFAVEE 624
N D P F YE V + GT V + D E + Y++ G G A +
Sbjct: 695 NDND-PYFDPKNYESVVSEDDPPGTPVTSVTATDPDEDARIHYEITAGNTRGRFAIASQN 753
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
G+IT+ L Y + V ++ + V++ D N+ V +S
Sbjct: 754 GRGLITIAQPLD-YKQEKRFVLTVTASDSGGRTDTALVYVNISDANNFSPVFENAPYSVS 812
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDDIAIAEDGTIFTQKP 743
+F ++ G + + T+ S + N N Q ++ I + G I T KP
Sbjct: 813 VF--EDAPIGTTVLVVSATD-SDVGKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKP 869
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE Y +TV A + G+ + V I + D NDN PVFE Y+G I E+ +G
Sbjct: 870 LDREIVPAYLLTVTAR-DGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVG 928
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T + + ATDAD N Y L +G F VD TG+++ LDRE Y L
Sbjct: 929 TSVLR---VSATDADTDLNGRVRYALEDDGDGAFAVDSTTGIIR-TAKPLDRESVAKYIL 984
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
VA D G LS+ + I I D ND+ P F EN K+ ++ N G T+ E+
Sbjct: 985 KAVAMDRGSPSLSTVVPVTIKIEDVNDSPPAF----ENDKIILY--IAENSPIGSTVGEI 1038
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+A D D+ GP NA+ S + G+ F + +
Sbjct: 1039 -----YAHDPDE-GP-----------------NAVVQYSVIGGEDSNSFALNIRPGADRA 1075
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
LE Y ++ V+ A S P S+ + I D VND+
Sbjct: 1076 ELITLEELDYESPKKKFELVVRAASPPLRSDALVQILVTD----------------VNDN 1119
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
PV K FN + + +GK+ A DAD LTY I + +++ +G
Sbjct: 1120 APVLKDFQIIFNNFKDFFPTAPIGKIPAIDADV--TDKLTYTILAGNNANLIDLNRTSGE 1177
Query: 1102 LSVNGELD 1109
+ ++ +L+
Sbjct: 1178 IRLSPQLN 1185
Score = 127 bits (307), Expect = 2e-27
Identities = 125/474 (26%), Positives = 211/474 (44%), Gaps = 46/474 (9%)
Query: 445 VEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++V +LD ND+ P F P E S++ VG+ + VKA D D G+N V Y + T+
Sbjct: 352 LQVNVLDTNDHAPSFEWPEE--EASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTT 409
Query: 504 NLTITSP------FKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLAV 554
+ + T+ F+I+P TG V+ +P+ + + + + SDQ PS R+ + A
Sbjct: 410 SSSGTANTEDALIFRIDPRTGVVT-TRTPLDREKTEVYTVILSVSDQATPPSARKTANAT 468
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRVNDAFEQND--VSYDL 610
+ + V + + P F Y W+ ++ + + +IR DA N+ V Y +
Sbjct: 469 LVVRVL----DDNDNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAI 524
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVD 668
+ G + F+++ G + +V L + Y + Q+ + S T VHV D
Sbjct: 525 IGGNTQNT-FSIDSMVGDVALVKPLDYESTRSYKI-VIRAQDGGSPARSNTTQLLVHVGD 582
Query: 669 VNDERGVLLKGAHSPIIFHVKEN-SAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDV 726
VND A H +E+ S +G I +++ I +
Sbjct: 583 VND-------NAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFT 635
Query: 727 ---TDDIAI---AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
T++ I E G ++T K LDRE+ Y+ TVIA + G IS + V + + D
Sbjct: 636 GASTENFPITVNTETGWLYTTKQLDREQCSRYQFTVIAA-DSGEISKSASATVILTVTDV 694
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV- 839
NDN P F+ YE + E+ GT + + ATD DE + T G + F +
Sbjct: 695 NDNDPYFDPKNYESVVSEDDPPGTPV---TSVTATDPDEDARIHYEITA-GNTRGRFAIA 750
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+N + I LD +++ + L++ A D+GG + A + + I D N+ P F
Sbjct: 751 SQNGRGLITIAQPLDYKQEKRFVLTVTASDSGGRTDTALVYVNISDANNFSPVF 804
Score = 127 bits (307), Expect = 2e-27
Identities = 135/460 (29%), Positives = 204/460 (44%), Gaps = 38/460 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+ D NDN+P F P N YE + + GT + V A DPD ++ + Y++ N
Sbjct: 687 VILTVTDVNDNDPYFDPKN-YESVVSEDDPPGTPVTSVTATDPD--EDARIHYEI-TAGN 742
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
G +++A+ P+ E R L V ASD S R A+V + ++
Sbjct: 743 TRGRFAIASQNGRGLITIAQ-PLDYKQEKRFVLTVTASD-----SGGRTDTALVYVNISD 796
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSYDLLHGYEEG 617
+ P F APY V + IGT+V + D+ Q S D +G +
Sbjct: 797 ANNFS----PVFENAPYSVSVFEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNGDQTA 852
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVL 676
F + ++G IT L R P Y A LS T+ + V DVND V
Sbjct: 853 SEFIINPQTGAITTTKPLDREIVPAYLLTVTARDGGIPPLSDTTDVEISVTDVNDNAPVF 912
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ I ++ G ++ ++ T+ + + G VR+ + + D + + G
Sbjct: 913 EAPQYQGSI--PEDVLVGTSVLRVSATDADT---DLNGRVRYALEDDGDGAFAVD-STTG 966
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T KPLDRE Y + +A ++G S + + VTI IED ND+PP FE+ +I
Sbjct: 967 IIRTAKPLDRESVAKYILKAVA-MDRGSPSLSTVVPVTIKIEDVNDSPPAFENDKIILYI 1025
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK---FIGDS 852
ENS IG+ + I A D DEG NA+ Y++ GE F ++ G + +
Sbjct: 1026 AENSPIGSTV---GEIYAHDPDEGPNAVVQYSVIGGEDSNSFALNIRPGADRAELITLEE 1082
Query: 853 LDREKKIMYKLSLVARDTG-GLSSEAELIIMIGDENDNKP 891
LD E K LV R L S+A + I++ D NDN P
Sbjct: 1083 LDYESP-KKKFELVVRAASPPLRSDALVQILVTDVNDNAP 1121
Score = 103 bits (248), Expect = 3e-20
Identities = 137/513 (26%), Positives = 212/513 (41%), Gaps = 70/513 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +P+G+T++ + A D D+G N ++ Y S + + DAL F I+ R G
Sbjct: 375 IREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDAL----IFRIDPRTG 430
Query: 1000 HVIVARSLPPESE--FRLNISALD-----GGNLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
V L E + + +S D N ++ V V D ND++P F + Y+
Sbjct: 431 VVTTRTPLDREKTEVYTVILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFTERTYSA 490
Query: 1053 NV-EEAQYTRR-VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+ E+ YT V+ ++ ATDAD G NA + Y I +T F I + G +++ LD
Sbjct: 491 WIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIGGNTQNTFSIDSMVGDVALVKPLDY 550
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADEL 1168
E+ Y + + A+D G DVNDN+P+FY F E + P
Sbjct: 551 ESTRSYKIVIRAQDGG-SPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVSENVPVG--- 606
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTV-AKVF--ANDTDF---IGNGNGLILYSLPQRK 1222
S++ I Y A NA I T+ A+ F A+ +F + G LY+ Q
Sbjct: 607 -----YSILRIQAYDADEGANAQIKYTIGARDFTGASTENFPITVNTETGW-LYTTKQLD 660
Query: 1223 NQQ-----------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
+Q + G S S++A +++TV DV D + P F + YE + E+
Sbjct: 661 REQCSRYQFTVIAADSGEISKSASATVILTVTDVND-----NDPYFDPKNYESVVSEDDP 715
Query: 1272 APVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ S+ T+ E+ ++ Y I N R F I +NG +
Sbjct: 716 PGTPVTSVTATDPDEDARIHYEITAGN---TRGRFAIASQNGR---------------GL 757
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
I A+ Y +E ++ A D G V V I D N+ SP F N P ++
Sbjct: 758 ITIAQPLDYKQEKRFVLTVTASD--SGGRTDTALVYVNISDANNFSPVFENA--PYSVSV 813
Query: 1392 PTTAPFGYQVMQLKGAIGH-HPTASRTVRADTD 1423
AP G V+ + A T DTD
Sbjct: 814 FEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTD 846
Score = 97.5 bits (232), Expect = 2e-18
Identities = 108/415 (26%), Positives = 180/415 (43%), Gaps = 37/415 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + DAN+ +PVF + Y S+ +A +GT + V A D D+G+N V Y L +
Sbjct: 790 VYVNISDANNFSPVFENAP-YSVSVFEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNG 848
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S F INP TG ++ + P+ + + L V A D P + + +V
Sbjct: 849 DQTASEFIINPQTGAITTTK-PLDREIVPAYLLTVTARDGGIPPLSDTTDVEISVTDV-- 905
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE--GVP 619
+ P F Y+ + +V +GTSV ++ DA D++ + + E+
Sbjct: 906 -----NDNAPVFEAPQYQGSIPEDVLVGTSVLRVSATDA--DTDLNGRVRYALEDDGDGA 958
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
FAV+ +G+I L R + Y +AVA+ + +LS V T+ + DVND
Sbjct: 959 FAVDSTTGIIRTAKPLDRESVAKYILKAVAMDRGSPSLSTVVPVTIKIEDVNDSPPAF-- 1016
Query: 679 GAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI----- 732
+ II ++ ENS G+ +G+I+ + V++ + +D ++ A+
Sbjct: 1017 -ENDKIILYIAENSPIGSTVGEIYAHDPDE---GPNAVVQYSVIGGED-SNSFALNIRPG 1071
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A+ + T + LD E V+ + + S A V I + D NDN PV +
Sbjct: 1072 ADRAELITLEELDYESPKKKFELVVRAASPPLRSDA---LVQILVTDVNDNAPVLKDFQ- 1127
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
I N K I A DAD T+ L L G + D++ +G ++
Sbjct: 1128 --IIFNNFKDFFPTAPIGKIPAIDADV-TDKLTYTILAGNNANLIDLNRTSGEIR 1179
Score = 92.7 bits (220), Expect = 7e-17
Identities = 55/177 (31%), Positives = 93/177 (52%), Gaps = 15/177 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G A +RY +I GN + FS+DS+ G + L K LD ++ ++ + ++
Sbjct: 507 IRATDADSGNNAAVRYAIIGGNTQNTFSIDSMVGDVALVKPLDYES-----TRSYKIVIR 561
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P ++ ++ + + D+NDN P F + S+ EN+P G+S+L++ A D D+G
Sbjct: 562 AQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGA 621
Query: 338 NGEFTYQLD--DPKGA------FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N + Y + D GA +++ +GWL Q LDRE S + V A ++
Sbjct: 622 NAQIKYTIGARDFTGASTENFPITVNTETGWLYTTKQ--LDREQCSRYQFTVIAADS 676
Score = 80.2 bits (189), Expect = 4e-13
Identities = 90/328 (27%), Positives = 142/328 (43%), Gaps = 46/328 (14%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG------------EKAFIFLIAPIGP------ 126
V++ DVNDN P F + + +V E P G E A + IG
Sbjct: 578 VHVGDVNDNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGA 637
Query: 127 -SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ P+TV + DR++ S +++++ D G + +S +L +
Sbjct: 638 STENFPITVNTETGWLYTTKQLDREQC----SRYQFTVIAA-DSGEISKSASATVILTVT 692
Query: 186 KVLDYDA--GDKEFQLVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRK 242
V D D K ++ V+ P+ ++ D A + YE+ +GN R
Sbjct: 693 DVNDNDPYFDPKNYESVVSEDDPP-------GTPVTSVTATDPDEDARIHYEITAGNTRG 745
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F++ S NG + LD + Q FVL V AS +T A V + + D N+
Sbjct: 746 RFAIASQNGRGLITIAQPLDYK---QEKRFVLTVTASDSGG--RTDTALVYVNISDANNF 800
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-----AFSIDPR 357
P FE Y++S+ E+ P G +VL V ATD D G+N + TY LD G F I+P+
Sbjct: 801 SPVFENAPYSVSVFEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNGDQTASEFIINPQ 860
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G +T LDRE + + V A++
Sbjct: 861 TGAITTTKP--LDREIVPAYLLTVTARD 886
Score = 79.0 bits (186), Expect = 9e-13
Identities = 60/178 (33%), Positives = 88/178 (49%), Gaps = 12/178 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D+G A + Y L + N + F ++ G++ K LD + ++L
Sbjct: 826 VSATDSDVGKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKPLDREI-----VPAYLL 880
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A P + VEI + D+NDN P FE Y SI E++ G SVL+V ATD D
Sbjct: 881 TVTARDGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVGTSVLRVSATDAD 940
Query: 335 QGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSV 390
NG Y L DD GAF++D +G +R LDRE+ + +K A + +PS+
Sbjct: 941 TDLNGRVRYALEDDGDGAFAVDSTTG--IIRTAKPLDRESVAKYILKAVAMDRGSPSL 996
Score = 68.9 bits (161), Expect = 1e-09
Identities = 67/244 (27%), Positives = 109/244 (44%), Gaps = 18/244 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L +VE+++ D NDN PVF + Y+ S+ + VGT + +V A D D NG V Y
Sbjct: 892 LSDTTDVEISVTDVNDNAPVF-EAPQYQGSIPEDVLVGTSVLRVSATDADTDLNGRVRYA 950
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L+ + F ++ TG + A+ P+ A ++ + S ++ VTI+
Sbjct: 951 LEDDGD----GAFAVDSTTGIIRTAK-PLDRESVAKYILKAVAMDRGSPSLSTVVPVTIK 1005
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEE 616
+ + P P F ++ N IG++VG+I +D E + V Y ++ G E+
Sbjct: 1006 IE--DVNDSP--PAFENDKIILYIAENSPIGSTVGEIYAHDPDEGPNAVVQYSVIGG-ED 1060
Query: 617 GVPFAVEERSGV----ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
FA+ R G + +++L Y P FE V + L + V DVND
Sbjct: 1061 SNSFALNIRPGADRAELITLEELD-YESPKKKFELVVRAASPPLRSDALVQILVTDVNDN 1119
Query: 673 RGVL 676
VL
Sbjct: 1120 APVL 1123
Score = 66.5 bits (155), Expect = 5e-09
Identities = 51/159 (32%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 228 GATLRYE---LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
G T+RY L+ + L LD V G + LD ++ + +V A + P
Sbjct: 290 GGTVRYSMSSLLDARSQALLVLDPVTGRVTTRARLDRES-----VDVHYFRVLAVDDSFP 344
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
+T +++ +LD ND+ P FE SI E +P G +V+ V ATD+D G N E Y
Sbjct: 345 PRTGTTTLQVNVLDTNDHAPSFEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYS 404
Query: 345 LDDPKGA-----------FSIDPRSGWLTVRNQTVLDRE 372
+ + F IDPR+G +T R T LDRE
Sbjct: 405 ILSTTSSSGTANTEDALIFRIDPRTGVVTTR--TPLDRE 441
Score = 60.1 bits (139), Expect = 5e-07
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 8/144 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D + +RY L D F++DS G + K LD ++ ++L+
Sbjct: 934 VSATDADTDLNGRVRYALEDDGDGA-FAVDSTTGIIRTAKPLDRES-----VAKYILKAV 987
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + V I++ D+ND+ P FE D + I EN P G +V ++ A D D+G
Sbjct: 988 AMDRGSPSLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENSPIGSTVGEIYAHDPDEGP 1047
Query: 338 NGEFTYQL--DDPKGAFSIDPRSG 359
N Y + + +F+++ R G
Sbjct: 1048 NAVVQYSVIGGEDSNSFALNIRPG 1071
Score = 55.2 bits (127), Expect = 1e-05
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLF--SLDSVNGSLFLEKELDLDAEHNLQANT 271
I A D D G A ++Y + +G + F ++++ G L+ K+LD + Q +
Sbjct: 612 IQAYDADEGANAQIKYTIGARDFTGASTENFPITVNTETGWLYTTKQLDRE-----QCSR 666
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ V A+ K+A A V + + D+NDN P F+ Y + E+ P G V V AT
Sbjct: 667 YQFTVIAADSGEISKSASATVILTVTDVNDNDPYFDPKNYESVVSEDDPPGTPVTSVTAT 726
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
D D+ + + +G F+I ++G + LD + + V A ++
Sbjct: 727 DPDEDARIHYEITAGNTRGRFAIASQNGRGLITIAQPLDYKQEKRFVLTVTASDS 781
Score = 54.0 bits (124), Expect = 3e-05
Identities = 52/183 (28%), Positives = 82/183 (44%), Gaps = 21/183 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGN---------DRKLFSLDSVNGSLFLEKELDLDAEHNLQ 268
+ A DQD G A + Y ++S D +F +D G + LD + +
Sbjct: 388 VKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRIDPRTGVVTTRTPLDRE---KTE 444
Query: 269 ANTFVLQVQASQLNNPL--KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS-- 324
T +L V + Q P KTA A + + +LD NDN P+F Y+ I E+L +
Sbjct: 445 VYTVILSV-SDQATPPSARKTANATLVVRVLDDNDNYPQFTERTYSAWIPEDLDYTANPV 503
Query: 325 VLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
+ ++ ATD D G N Y + + + FSID G V LD E+ S ++ +
Sbjct: 504 IARIRATDADSGNNAAVRYAIIGGNTQNTFSIDSMVG--DVALVKPLDYESTRSYKIVIR 561
Query: 383 AKE 385
A++
Sbjct: 562 AQD 564
Score = 52.8 bits (121), Expect = 7e-05
Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 63/423 (14%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
++E RL I L+D R +++ + P F+++ Y VEE + + V A
Sbjct: 227 DAEHRLKI-VFHHRQLDDTDLGRRVRRELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRA 285
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
D + G + + + + P+TG ++ LDRE+ D + V+A D+
Sbjct: 286 RDPEGGTVRYSMSSLLDARSQALLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDD-SFP 344
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE- 1188
D ND++P F EW PE + + KAT ++
Sbjct: 345 PRTGTTTLQVNVLDTNDHAPSF-------EW--PEEEASIREGVPVGSTVVTVKATDQDA 395
Query: 1189 --NAPI-----GTTVAKVFANDTDF----IGNGNGLILYSLPQRKNQQNLGL-------- 1229
NA + TT + AN D I G++ P + + +
Sbjct: 396 GRNAEVEYSILSTTSSSGTANTEDALIFRIDPRTGVVTTRTPLDREKTEVYTVILSVSDQ 455
Query: 1230 ---PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV----NAPVELVSLNLT 1282
PS TA + V + D + P F R Y I E++ N + +
Sbjct: 456 ATPPSARKTANATLVVRVLDDN---DNYPQFTERTYSAWIPEDLDYTANPVIARIRATDA 512
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
+ N +RY I+ N + TF ID G + LV+ D E +Y++++R
Sbjct: 513 DSGNNAAVRYAIIGGN---TQNTFSIDSMVGDVALVKPLDYESTRSYKIVIR-------- 561
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVM 1402
A+D +++V + DVNDN+P+F + ++ P GY ++
Sbjct: 562 ---------AQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSH--FQESVSENVPVGYSIL 610
Query: 1403 QLK 1405
+++
Sbjct: 611 RIQ 613
Score = 46.4 bits (105), Expect = 0.006
Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 30/149 (20%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
V + G +S + VT+ IEDVND+ P F + + + E +P G + +G
Sbjct: 987 VAMDRGSPSLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENSPIG--------STVG-- 1036
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE---SSHKPVLLL 184
+I A D D+ PN+ V YS++ G D FAL + + L+
Sbjct: 1037 ---------------EIYAHDPDEG--PNAVVQYSVIGGEDSNSFALNIRPGADRAELIT 1079
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEIL 213
+ LDY++ K+F+LV+ A+ + + L
Sbjct: 1080 LEELDYESPKKKFELVVRAASPPLRSDAL 1108
Score = 41.1 bits (92), Expect = 0.23
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 6/98 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I+A D D G A ++Y +I G D F+L+ G+ E + ++ F L V+
Sbjct: 1038 IYAHDPDEGPNAVVQYSVIGGEDSNSFALNIRPGADRAELITLEELDYESPKKKFELVVR 1097
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLP---EFEVDFYN 312
A+ + PL++ A V+I + D+NDN P +F++ F N
Sbjct: 1098 AA--SPPLRS-DALVQILVTDVNDNAPVLKDFQIIFNN 1132
Score = 36.7 bits (81), Expect = 4.9
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 4/60 (6%)
Query: 144 IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMA 203
IRA D D N N+ V Y+I+ GN F+++S V L+ K LDY++ + +++VI A
Sbjct: 507 IRATDADSGN--NAAVRYAIIGGNTQNTFSIDSMVGDVALV-KPLDYES-TRSYKIVIRA 562
>UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio
"Protocadherin1-alpha-av15-vCP.; n=1; Takifugu
rubripes|Rep: Homolog of Brachydanio rerio
"Protocadherin1-alpha-av15-vCP. - Takifugu rubripes
Length = 1420
Score = 140 bits (339), Expect = 3e-31
Identities = 207/779 (26%), Positives = 320/779 (41%), Gaps = 98/779 (12%)
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN--TGTVSVAES 525
++ ++K GTVI + D D G NG ++ S +T PF++ P+ T S+
Sbjct: 236 TVPEDSKPGTVISLISVSDKDSGVNGKII------SRITSDVPFELKPSYKENTYSIVTK 289
Query: 526 PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
L+ E Q + E S V +I+V + P F+ P +F++ N
Sbjct: 290 AFLDREMTSHYEIIIQAVDCGEPPLS-TVRSIQVQ--VSDINDNSPRFIQNPLQFYLVEN 346
Query: 586 VGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMY 643
G S+ + ND E +SY + + V +G I+ + +
Sbjct: 347 NVAGASIFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFDFETLKTF 406
Query: 644 DFEAVALQENANLSIVTNATVHV--VDVNDERGVLLKGAHSPIIFH-VKENSAGAAIGQI 700
F+ VA ++ + S+ +N TV+V +D ND V+L S V+E G +
Sbjct: 407 QFQVVA-SDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHL 465
Query: 701 FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI---FTQKPLDREKRDVYRMTVI 757
T + + Y G +L+ + Q V+D ED + QK LDRE +++ +
Sbjct: 466 V-TKVRA-YDADIGYNGWLLFSLQQVSDHSLFGEDRKVPFLVLQKQLDRETASSHKLQLT 523
Query: 758 AEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
A + G + +G + I + D NDN PVF Y I EN IGT + I ATD
Sbjct: 524 A-LDGGKPAKSGAIDIIIDVLDVNDNSPVFAKELYSSTIKENVPIGTVVIQ---INATDL 579
Query: 818 DEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA 877
DEG N +Y GKEM + K+M + DT + E
Sbjct: 580 DEGANGEIIYMF---GKEM-------------------DSKLMNVFDI---DTN--TGEI 612
Query: 878 ELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPL 937
+I I E E + I+ + K + T + + ++I++ N A +++
Sbjct: 613 RVIGKIDFEESRSFELD-IQASDKAQAPLTT--DKSVMISVIDI---NDNAPEIEVTSFS 666
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
I E+ +GTT+ ++ DLDSG+NG++ + P LS +L+ Y V+
Sbjct: 667 SSIKEDSKLGTTVALISVSDLDSGINGKVICSLKED---SPFNLSP-SLQNNMYAVVTRS 722
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ R + S++ L I A D G ++ + V DVND+ P F + Y F V
Sbjct: 723 Q----LDREIV--SKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVT 776
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT-DLPF----EISPLTGVLSVNGELDR 1110
E + V A+D D NA +TY I+ T D F I+ TG + D
Sbjct: 777 ENNSPGASVFSVKASDCDENNNAMITYHIRRERTLDANFASFLNINSETGDIFALKSFDF 836
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
ET + VVA D+G D NDN+P +P + SN
Sbjct: 837 ETLKTFQFQVVASDSG-SPSLSSNVTVNVFILDQNDNAPVIL---------YPVS---SN 883
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
+ E V IP N G V KV A D D IG NG +L+SL Q + GL
Sbjct: 884 GSAEGVEEIP-------RNVNAGHLVTKVRAYDAD-IGY-NGWLLFSLQQVSDHSLFGL 933
Score = 126 bits (305), Expect = 4e-27
Identities = 127/466 (27%), Positives = 208/466 (44%), Gaps = 35/466 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+NV + +LD NDN P F + Y+ + N VG + KV A+D D G NG + Y L +T
Sbjct: 107 LNVSIIVLDNNDNIPRF-DKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKT 165
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F++NP G + + E + L +EASD+ P R + V I+V
Sbjct: 166 LVRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRVIVKVIDVK 225
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ N+ DI + V + GT + I V+D + + V+ ++ VPF
Sbjct: 226 --SSRNRSDITN--------TVPEDSKPGTVISLISVSD--KDSGVNGKIISRITSDVPF 273
Query: 621 ----AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGV 675
+ +E + I L R Y+ A+ LS V + V V D+ND
Sbjct: 274 ELKPSYKENTYSIVTKAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDINDNSPR 333
Query: 676 LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-A 733
++ +P+ F++ EN+ AGA+I + T+ + + N + + IA DVT + + +
Sbjct: 334 FIQ---NPLQFYLVENNVAGASIFSVSATD-NDVSENAV--ISYSIARLNDVTSFLNVNS 387
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G I K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 388 ENGQISALKSFDFETLKTFQFQVVAS-DSGSPSLSSNVTVNVFILDQNDNAPVILYPVSS 446
Query: 794 GFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
E +I + ++ ++A DAD G N +++L ++ +
Sbjct: 447 NGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFGEDRKVPFLVL 506
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
LDRE +KL L A D G S ++II + D NDN P F
Sbjct: 507 QKQLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVF 552
Score = 124 bits (299), Expect = 2e-26
Identities = 112/459 (24%), Positives = 208/459 (45%), Gaps = 36/459 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+++ + +LD NDN+PVF LY ++K N +GTV+ ++ A D D G NG ++Y +
Sbjct: 536 IDIIIDVLDVNDNSPVFA-KELYSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKE 594
Query: 503 SNLTITSPFKINPNTGTVSV-AESPILEGR-HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ + + F I+ NTG + V + E R L ++ASD+ P S+ + I++
Sbjct: 595 MDSKLMNVFDIDTNTGEIRVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDI- 653
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P+I + + + +GT+V I V+D + ++ ++ +E PF
Sbjct: 654 ---NDNAPEIE---VTSFSSSIKEDSKLGTTVALISVSDL--DSGINGKVICSLKEDSPF 705
Query: 621 ----AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERG 674
+++ + L R YD VA ++ + +T T+ ++ DVND
Sbjct: 706 NLSPSLQNNMYAVVTRSQLDREIVSKYDLTIVA-KDTGEPTFLTEKTISLIVSDVNDNSP 764
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-- 732
L ++ F+V EN++ A +F S N + + I ++ + + A
Sbjct: 765 KFLSSSYG---FYVTENNSPGA--SVFSVKASDCDENNNAMITYHIRRERTLDANFASFL 819
Query: 733 ---AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+E G IF K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 820 NINSETGDIFALKSFDFETLKTFQFQVVAS-DSGSPSLSSNVTVNVFILDQNDNAPVILY 878
Query: 790 ATYEGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTG 844
E +I + ++ ++A DAD G N +++L +F +D TG
Sbjct: 879 PVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFGLDRYTG 938
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ + S + +KL ++ +D G +S A +M+
Sbjct: 939 QIRTL-RSFTETDEAEHKLVILVKDNGNVSLSATATVMV 976
Score = 116 bits (279), Expect = 5e-24
Identities = 131/477 (27%), Positives = 206/477 (43%), Gaps = 42/477 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQN 492
L S V V V +LD NDN PV V SN ++ N G ++ KV+A D D+G N
Sbjct: 856 LSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYN 915
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRY 550
G +L+ LQ+ S+ ++ F ++ TG + S E H L + D
Sbjct: 916 GWLLFSLQQVSDHSL---FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATA 972
Query: 551 SLAVVTIE-----VTRGTKGNKPDIPDFM-GAPYEFWVGSNVGIGT-SVGQIRVNDAFEQ 603
++ V +E + + D D + GA ++ + G SV +++ Q
Sbjct: 973 TVMVKLVEPKEAFAASDLQSSAKDDEDMLAGARFQLKGAQDADSGRFSVQHYKLS----Q 1028
Query: 604 NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNA 662
ND H E + + ++ V L R + AL S N
Sbjct: 1029 ND------HFRLEVKDRGKDGKIPILVVQKSLDRETAGSHSLVLTALDGGKPPKSGEMNI 1082
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
++V+D+ND V K +S ++ H EN+ G + Q+ T+ NG F +
Sbjct: 1083 LINVLDINDNAPVFSKDVYS-VMLH--ENTLIGTTVIQVNATDADD-GPNGEVVYSFSNS 1138
Query: 722 NQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
Q+V D I E G I + P+D E+ + Y + V A +KG + V I I D
Sbjct: 1139 MNQNVLDLFDINEITGEITVKGPIDYEENERYEIEVEAS-DKGFVPLKTEKTVIIDITDV 1197
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P E ++ FI E+S+ GT + I D D G N + T+ +
Sbjct: 1198 NDNAPEIEVTSFSSFIPEDSRPGTTVAH---ISVNDLDSGINGKVICTISNDSPFALTPS 1254
Query: 841 ENTGVVKFIGDS-LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
+ + S LDRE++ Y L++ A+D G LSSE + +++ D NDN+PEF+
Sbjct: 1255 LKDKMFSLVTKSALDREQRDKYDLTITAKDAGQLSLSSEKTITVVVSDVNDNRPEFS 1311
Score = 102 bits (245), Expect = 7e-20
Identities = 98/359 (27%), Positives = 166/359 (46%), Gaps = 34/359 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+N+ + +LD NDN PVF ++Y + N +GT + +V A D D G NG V+Y +
Sbjct: 1080 MNILINVLDINDNAPVF-SKDVYSVMLHENTLIGTTVIQVNATDADDGPNGEVVYSFSNS 1138
Query: 503 SNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
N + F IN TG ++V + PI R+ + VEASD+ P + V I++
Sbjct: 1139 MNQNVLDLFDINEITGEITV-KGPIDYEENERYEIEVEASDKGFVPLKTE---KTVIIDI 1194
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T N P+I + ++ + GT+V I VND + ++ ++ P
Sbjct: 1195 T-DVNDNAPEIE---VTSFSSFIPEDSRPGTTVAHISVNDL--DSGINGKVICTISNDSP 1248
Query: 620 FA----VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDER 673
FA ++++ + L R R YD + ++ LS+ + T+ VV DVND R
Sbjct: 1249 FALTPSLKDKMFSLVTKSALDREQRDKYDL-TITAKDAGQLSLSSEKTITVVVSDVNDNR 1307
Query: 674 GVLLKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQDVTD 728
+ + SP F++ E N G + +F N +V + I + + ++
Sbjct: 1308 P---EFSLSPYTFYISEANQPGTS---VFSVKAFDRDDNDNAHVSYHILRDGSPENKLSS 1361
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
++I +E G I K D E + ++ V+A + G S + V ++I D+NDN PV
Sbjct: 1362 FLSINSETGDILALKSFDFEAQKTFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPV 1419
Score = 99.1 bits (236), Expect = 8e-19
Identities = 92/376 (24%), Positives = 163/376 (43%), Gaps = 31/376 (8%)
Query: 530 GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG 589
G H+L + A D P ++ + +++ + P F Y + N IG
Sbjct: 1060 GSHSLVLTALDGGKPPKSGEMNILINVLDIN-------DNAPVFSKDVYSVMLHENTLIG 1112
Query: 590 TSVGQIRVNDAFE--QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDF 645
T+V Q+ DA + +V Y + + V F + E +G ITV + Y+
Sbjct: 1113 TTVIQVNATDADDGPNGEVVYSFSNSMNQNVLDLFDINEITGEITVKGPIDYEENERYEI 1172
Query: 646 EAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
E A + L + + DVND + + S I +++ G + H +
Sbjct: 1173 EVEASDKGFVPLKTEKTVIIDITDVNDNAPEIEVTSFSSFI--PEDSRPGTTVA---HIS 1227
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG-TIFTQKPLDREKRDVYRMTVIAEFNKG 763
++ + G V I+N ++ + ++ T+ LDRE+RD Y +T+ A+ + G
Sbjct: 1228 VNDLDSGINGKVICTISNDSPFALTPSLKDKMFSLVTKSALDREQRDKYDLTITAK-DAG 1286
Query: 764 VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA 823
+S + +T+ + D NDN P F + Y +I E ++ GT + +KA D D+ NA
Sbjct: 1287 QLSLSSEKTITVVVSDVNDNRPEFSLSPYTFYISEANQPGTSVFS---VKAFDRDDNDNA 1343
Query: 824 LFMYTLFGEG------KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSS 875
Y + +G ++ TG + + S D E + ++ +VA D+G LSS
Sbjct: 1344 HVSYHILRDGSPENKLSSFLSINSETGDILAL-KSFDFEAQKTFQFQVVASDSGSPSLSS 1402
Query: 876 EAELIIMIGDENDNKP 891
+ + I D+NDN P
Sbjct: 1403 NVTVKVFILDQNDNAP 1418
Score = 95.5 bits (227), Expect = 1e-17
Identities = 174/733 (23%), Positives = 289/733 (39%), Gaps = 92/733 (12%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V ++++D NDN P ++ + S+K ++K+GT + + D D G NG V+ L+ S
Sbjct: 645 SVMISVIDINDNAPEIEVTS-FSSSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDS 703
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD--QPANPSERRYSLAVVTIEVTR 561
++ + N + ++ L + A D +P +E+ SL V +
Sbjct: 704 PFNLSPSLQNNMYAVVTRSQLDREIVSKYDLTIVAKDTGEPTFLTEKTISLIVSDVN--- 760
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
+ P F+ + Y F+V N G SV ++ +D E N+ ++Y +
Sbjct: 761 ------DNSPKFLSSSYGFYVTENNSPGASVFSVKASDCDENNNAMITYHIRRERTLDAN 814
Query: 620 FA----VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDVNDER 673
FA + +G I + + F+ VA ++ + S+ +N TV+V +D ND
Sbjct: 815 FASFLNINSETGDIFALKSFDFETLKTFQFQVVA-SDSGSPSLSSNVTVNVFILDQNDNA 873
Query: 674 GVLLKGAHSPIIFH-VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V+L S V+E G + T + + Y G +L+ + Q V+D
Sbjct: 874 PVILYPVSSNGSAEGVEEIPRNVNAGHLV-TKVRA-YDADIGYNGWLLFSLQQVSDHSLF 931
Query: 733 AED---GTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTIYIEDENDNPPVFE 788
D G I T + +++ ++ + N V +S V + E +
Sbjct: 932 GLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVMVKLVEPKEAFAASDLQ 991
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN--TGVV 846
+ + E+ G ++ A DAD G ++ Y L +V + G +
Sbjct: 992 SSAKDD---EDMLAGARFQLKG---AQDADSGRFSVQHYKLSQNDHFRLEVKDRGKDGKI 1045
Query: 847 KF--IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ SLDRE + L L A D G S E ++I + D NDN P F+ ++ V
Sbjct: 1046 PILVVQKSLDRETAGSHSLVLTALDGGKPPKSGEMNILINVLDINDNAPVFS--KDVYSV 1103
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
+H T + G T+I+V A D D GP E + + + N LDL +
Sbjct: 1104 MLHENTLI----GTTVIQVN-----ATDADD-GP---NGEVVYSFSNSMNQNVLDL-FDI 1149
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDG 1022
N E E+ + K D E +RY + E V P ++E + I D
Sbjct: 1150 N-----EITGEITV---KGPIDYEENERYEIEVEASDKGFV----PLKTEKTVIIDITD- 1196
Query: 1023 GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
+NDN P + T ++ + E + + D D G N +
Sbjct: 1197 --VNDNA-------------PEIEVTSFSSFIPEDSRPGTTVAHISVNDLDSGINGKVIC 1241
Query: 1083 FIQPSDTDLPFEISPLTG----VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
I D PF ++P L LDRE DKY LT+ A+D G
Sbjct: 1242 TI---SNDSPFALTPSLKDKMFSLVTKSALDREQRDKYDLTITAKDAG-QLSLSSEKTIT 1297
Query: 1139 XXXXDVNDNSPKF 1151
DVNDN P+F
Sbjct: 1298 VVVSDVNDNRPEF 1310
Score = 87.4 bits (207), Expect = 3e-15
Identities = 115/494 (23%), Positives = 195/494 (39%), Gaps = 40/494 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D ND++P F P F M + GT A DPD G N + Y L +
Sbjct: 1 VVVEITDVNDHSPSF-PETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDH 59
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
I T + + +S E +H+L V A D +++++ ++
Sbjct: 60 FGIEMSQSDEEKTPFLVLKQSLDREKSNKHSLVVTAVDGGKPQRSGTLNVSIIVLD---- 115
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV-- 618
N +IP F Y+ + NV +G +V ++ D E ++ Y L V
Sbjct: 116 ---NNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKTLVRNVYD 172
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
F + +G I + L Y + A + V V+DV R
Sbjct: 173 IFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRVIVKVIDVKSSRN--- 229
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIA-ED 735
S I V E+S + ++ S+ +G N + + DV ++ + ++
Sbjct: 230 ---RSDITNTVPEDSKPGTV-----ISLISVSDKDSGVNGKIISRITSDVPFELKPSYKE 281
Query: 736 GT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
T I T+ LDRE Y + +I + G + + + + + D NDN P F +
Sbjct: 282 NTYSIVTKAFLDREMTSHYEI-IIQAVDCGEPPLSTVRSIQVQVSDINDNSPRFIQNPLQ 340
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDENTGVVKFIGD 851
+++EN+ G I + ATD D NA+ Y++ + +V+ G + +
Sbjct: 341 FYLVENNVAGASIFS---VSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISAL-K 396
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE-FNQIEENSKVRIHRET 908
S D E ++ +VA D+G LSS + + I D+NDN P + N E
Sbjct: 397 SFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEI 456
Query: 909 KLNGTAGFTIIEVK 922
N AG + +V+
Sbjct: 457 PRNVNAGHLVTKVR 470
Score = 86.6 bits (205), Expect = 5e-15
Identities = 86/337 (25%), Positives = 146/337 (43%), Gaps = 30/337 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPS 127
+ G +S S+ V + D+NDN P F+ P + E G F + +
Sbjct: 307 VDCGEPPLSTVRSIQVQVSDINDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSEN 366
Query: 128 LTIPLTVPR--GLTIFKDIRAFDRDKPNTPNSDVH------YSIVSGNDDGHFALESSHK 179
I ++ R +T F ++ + + + D + +V+ +D G +L S+
Sbjct: 367 AVISYSIARLNDVTSFLNVNSENGQISALKSFDFETLKTFQFQVVA-SDSGSPSLSSNVT 425
Query: 180 P-VLLLRK-----VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
V +L + V+ Y + + ++ L + + A D D+G L +
Sbjct: 426 VNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTK-VRAYDADIGYNGWLLF 484
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
L +D LF D L L+K+LD + A++ LQ+ A P K+ +
Sbjct: 485 SLQQVSDHSLFGEDRKVPFLVLQKQLDRET-----ASSHKLQLTALDGGKPAKSGAIDII 539
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPK- 349
I++LD+NDN P F + Y+ +I EN+P G V+Q+ ATD D+G NGE Y D K
Sbjct: 540 IDVLDVNDNSPVFAKELYSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSKL 599
Query: 350 -GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F ID +G + V + +D E S + + A +
Sbjct: 600 MNVFDIDTNTGEIRVIGK--IDFEESRSFELDIQASD 634
Score = 82.6 bits (195), Expect = 8e-14
Identities = 119/475 (25%), Positives = 202/475 (42%), Gaps = 73/475 (15%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN G +I ++A D D N I Y ++L+ +V + +N
Sbjct: 341 FYLVENNVAGASIFSVSATDNDVSENAVISYSI--------ARLN----DVTSFLNVNSE 388
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNF 1052
+G + +S E+ F+ + A D G+ L+ N++V VF+ D ND+ PV N
Sbjct: 389 NGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNG 448
Query: 1053 NVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ E + R ++ KV A DAD G N L + +Q F L +
Sbjct: 449 SAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFGEDRKVPFLVLQK 508
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
+LDRET + L + A D G DVNDNSP F A
Sbjct: 509 QLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVL-DVNDNSPVF-------------AK 554
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
EL Y +TI+EN PIGT V ++ A D D NG + ++ N
Sbjct: 555 EL-------------YSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSKLMN 601
Query: 1227 LGLPSLSSTAILMVTVADVPD------EVEMSDK---PVFISRYYELE-IEENVNAP-VE 1275
+ ++ I ++ D + +++ SDK P+ + + I+ N NAP +E
Sbjct: 602 VFDIDTNTGEIRVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAPEIE 661
Query: 1276 LVSLNLTEHYENFKMRYYI----LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ S + + E+ K+ + +++ D+ I + + + + + SP + + Y V
Sbjct: 662 VTSFS-SSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDSPFNL-SPSLQ-NNMYAV 718
Query: 1332 IVRAERQKYSREL--PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
+ R++ RE+ + + VA+D E + + + + DVNDNSPKF + +
Sbjct: 719 VTRSQ---LDREIVSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSS 770
Score = 82.6 bits (195), Expect = 8e-14
Identities = 95/355 (26%), Positives = 162/355 (45%), Gaps = 30/355 (8%)
Query: 1001 VIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
++V +SL E+ L ++ALDGG + +++ + V D+ND+ PVF K Y+ + E
Sbjct: 1048 LVVQKSLDRETAGSHSLVLTALDGGKPPKSGEMNILINVLDINDNAPVFSKDVYSVMLHE 1107
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDT----DLPFEISPLTGVLSVNGELDRET 1112
+ +V+ATDAD G N + Y S DL F+I+ +TG ++V G +D E
Sbjct: 1108 NTLIGTTVIQVNATDADDGPNGEVVYSFSNSMNQNVLDL-FDINEITGEITVKGPIDYEE 1166
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELL-EWKHP--EADE 1167
++Y + V A D G DVNDN+P+ +F + E P
Sbjct: 1167 NERYEIEVEASDKG-FVPLKTEKTVIIDITDVNDNAPEIEVTSFSSFIPEDSRPGTTVAH 1225
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVA---KVFANDTDFIGNGNGLILYSLPQRKNQ 1224
+S ++ +S + V TI ++P T + K+F+ T + Y L
Sbjct: 1226 ISVNDLDSGINGKVI-CTISNDSPFALTPSLKDKMFSLVTKSALDREQRDKYDL--TITA 1282
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL--T 1282
++ G SLSS + V V+DV D ++P F Y I E + S+
Sbjct: 1283 KDAGQLSLSSEKTITVVVSDVND-----NRPEFSLSPYTFYISEANQPGTSVFSVKAFDR 1337
Query: 1283 EHYENFKMRYYILNENDTDIR-RTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ +N + Y+IL + + + +F+ I+ G + ++S D E + T++ V A
Sbjct: 1338 DDNDNAHVSYHILRDGSPENKLSSFLSINSETGDILALKSFDFEAQKTFQFQVVA 1392
Score = 77.4 bits (182), Expect = 3e-12
Identities = 122/484 (25%), Positives = 191/484 (39%), Gaps = 60/484 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+P+G T+ K++A+D D G NG+I Y + + V F +N +G
Sbjct: 132 ISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKTL----------VRNVYDIFELNPLNG 181
Query: 1000 HVIVARSLP-PESE-FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L ESE ++L+I A D G RV VK V D ++ V E
Sbjct: 182 EIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRVIVK-VIDVKSSRNRSDITNTVPED 240
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL----TGVLSVNGELDRETE 1113
V+ + +D D G N + I +D+PFE+ P T + LDRE
Sbjct: 241 SKPGTVISLISVSDKDSGVNGKI---ISRITSDVPFELKPSYKENTYSIVTKAFLDREMT 297
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y + + A D G D+NDNSP+F L++ E +N
Sbjct: 298 SHYEIIIQAVDCG-EPPLSTVRSIQVQVSDINDNSPRF--IQNPLQFYLVE----NNVAG 350
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKV-----FANDTDFIGNGNGLILYSLPQRKNQQ--- 1225
S+ + + ENA I ++A++ F N G + L + K Q
Sbjct: 351 ASIFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFDFETLKTFQFQV 410
Query: 1226 ---NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE--LEIEENVNAPVELVSLN 1280
+ G PSLSS + V + D D + PV + E EI NVNA LV+
Sbjct: 411 VASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAG-HLVT-- 467
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
K+R Y + D + + + + + DR+V +V ++
Sbjct: 468 --------KVRAY---DADIGYNGWLLFSLQQVSDHSLFGEDRKV----PFLVLQKQLDR 512
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQ 1400
H + A D + + +++ + DVNDNSP F + I P G
Sbjct: 513 ETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVF--AKELYSSTIKENVPIGTV 570
Query: 1401 VMQL 1404
V+Q+
Sbjct: 571 VIQI 574
Score = 74.5 bits (175), Expect = 2e-11
Identities = 72/265 (27%), Positives = 116/265 (43%), Gaps = 23/265 (8%)
Query: 897 EENSKVRIHRETKLNG-----TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
EEN + I E G T II++ N A +++ IPE+ GTT+
Sbjct: 1165 EENERYEIEVEASDKGFVPLKTEKTVIIDITDVNDNAPEIEVTSFSSFIPEDSRPGTTVA 1224
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
++ DLDSG+NG++ +++ P L+ +L+ K + ++ + A
Sbjct: 1225 HISVNDLDSGINGKVICTISND---SPFALT-PSLKDKMFSLVTKS------ALDREQRD 1274
Query: 1012 EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
++ L I+A D G +L+ ++ V V DVND+ P F + Y F + EA + V A
Sbjct: 1275 KYDLTITAKDAGQLSLSSEKTITVVVSDVNDNRPEFSLSPYTFYISEANQPGTSVFSVKA 1334
Query: 1070 TDADFGQNANLTYFI----QPSDTDLPF-EISPLTGVLSVNGELDRETEDKYILTVVARD 1124
D D NA+++Y I P + F I+ TG + D E + + VVA D
Sbjct: 1335 FDRDDNDNAHVSYHILRDGSPENKLSSFLSINSETGDILALKSFDFEAQKTFQFQVVASD 1394
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSP 1149
+G D NDN+P
Sbjct: 1395 SG-SPSLSSNVTVKVFILDQNDNAP 1418
Score = 74.1 bits (174), Expect = 3e-11
Identities = 55/176 (31%), Positives = 87/176 (49%), Gaps = 14/176 (7%)
Query: 218 IHAI-DQDLGVGATLRYELISGNDRKLFSLDSVNGSL--FLEKELDLDAEHNLQANTFVL 274
+HA D D G+ + Y ++S ND + + FL + LD E ++N L
Sbjct: 36 LHAARDPDTGLNSIRTY-ILSANDHFGIEMSQSDEEKTPFLVLKQSLDRE---KSNKHSL 91
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A P ++ V I +LD NDN+P F+ D Y I I EN+P G +V +V A D+D
Sbjct: 92 VVTAVDGGKPQRSGTLNVSIIVLDNNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQD 151
Query: 335 QGENGEFTYQLD-----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G NGE Y L + F ++P +G +R + +LD E + ++ + A +
Sbjct: 152 EGANGEIEYSLSKTLVRNVYDIFELNPLNG--EIRLKGMLDFEESETYKLDIEASD 205
Score = 70.1 bits (164), Expect = 4e-10
Identities = 51/174 (29%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
I+A D D G + Y D KL F +D+ G + + ++D + ++ +F L
Sbjct: 574 INATDLDEGANGEIIYMFGKEMDSKLMNVFDIDTNTGEIRVIGKIDFE-----ESRSFEL 628
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+QAS T V I ++D+NDN PE EV ++ SI E+ G +V + +D D
Sbjct: 629 DIQASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVALISVSDLD 688
Query: 335 QGENGEFTYQLDDPKGAFSIDP--RSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
G NG+ L + F++ P ++ V ++ LDRE S + + AK+T
Sbjct: 689 SGINGKVICSLKE-DSPFNLSPSLQNNMYAVVTRSQLDREIVSKYDLTIVAKDT 741
Score = 66.9 bits (156), Expect = 4e-09
Identities = 56/216 (25%), Positives = 95/216 (43%), Gaps = 17/216 (7%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++E+ N + + F + E+ GT A D D+GLN Y ++ +
Sbjct: 2 VVEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDHFG 61
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
+D E+ +++ +SL E ++ L ++A+DGG + ++V +
Sbjct: 62 IEMSQSD----------EEKTPFLVLKQSLDREKSNKHSLVVTAVDGGKPQRSGTLNVSI 111
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS---DTD 1090
V D ND+ P F K Y + E R + KV A D D G N + Y + + +
Sbjct: 112 IVLDNNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKTLVRNVY 171
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
FE++PL G + + G LD E + Y L + A D G
Sbjct: 172 DIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKG 207
Score = 65.3 bits (152), Expect = 1e-08
Identities = 52/173 (30%), Positives = 81/173 (46%), Gaps = 12/173 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD-SVNGSL-FLEKELDLDAEHNLQANTFVLQVQ 277
A D D G + Y+L + +L D +G + L + LD E A + L +
Sbjct: 1011 AQDADSGRFSVQHYKLSQNDHFRLEVKDRGKDGKIPILVVQKSLDRE---TAGSHSLVLT 1067
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K+ + + I +LD+NDN P F D Y++ + EN G +V+QV ATD D G
Sbjct: 1068 ALDGGKPPKSGEMNILINVLDINDNAPVFSKDVYSVMLHENTLIGTTVIQVNATDADDGP 1127
Query: 338 NGEFTYQLDDPKG-----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NGE Y + F I+ +G +TV+ +D E + ++V A +
Sbjct: 1128 NGEVVYSFSNSMNQNVLDLFDINEITGEITVKGP--IDYEENERYEIEVEASD 1178
Score = 58.0 bits (134), Expect = 2e-06
Identities = 44/173 (25%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y ++ N LF ++ + G + ++ +D + + +
Sbjct: 1118 VNATDADDGPNGEVVYSFSNSMNQNVLDLFDINEITGEITVKGPIDYEENERYE-----I 1172
Query: 275 QVQASQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+V+AS PLKT + V I++ D+NDN PE EV ++ I E+ G +V + D
Sbjct: 1173 EVEASDKGFVPLKTEKT-VIIDITDVNDNAPEIEVTSFSSFIPEDSRPGTTVAHISVNDL 1231
Query: 334 DQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G NG+ + +D A + + ++ ++ LDRE + + AK+
Sbjct: 1232 DSGINGKVICTISNDSPFALTPSLKDKMFSLVTKSALDREQRDKYDLTITAKD 1284
Score = 55.6 bits (128), Expect = 1e-05
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 29/333 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V V I DVND+ P F +T + E T G + + L T
Sbjct: 1 VVVEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDHF 60
Query: 143 DIRAFDRDKPNTP-----------NSDVHYSIVSGNDDGHFALESS-HKPVLLLRKVLDY 190
I D+ TP S+ H +V+ D G + + +++L +
Sbjct: 61 GIEMSQSDEEKTPFLVLKQSLDREKSNKHSLVVTAVDGGKPQRSGTLNVSIIVLDNNDNI 120
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL---ISGNDRKLFSLD 247
DK+ + ++ + + + + AIDQD G + Y L + N +F L+
Sbjct: 121 PRFDKDTYQIEISENVPVGRTVT---KVSAIDQDEGANGEIEYSLSKTLVRNVYDIFELN 177
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
+NG + L+ LD + ++ T+ L ++AS P ++ RV ++++D+ + +
Sbjct: 178 PLNGEIRLKGMLDFE-----ESETYKLDIEASDKGTPPFRSRCRVIVKVIDVKSSRNRSD 232
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP--RSGWLTVRN 365
+ ++ E+ G + + +DKD G NG+ ++ F + P + ++
Sbjct: 233 I---TNTVPEDSKPGTVISLISVSDKDSGVNGKIISRITSDV-PFELKPSYKENTYSIVT 288
Query: 366 QTVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
+ LDRE S + + A + + T Q
Sbjct: 289 KAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQ 321
Score = 55.2 bits (127), Expect = 1e-05
Identities = 108/465 (23%), Positives = 184/465 (39%), Gaps = 68/465 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IP N+ G + K+ A D D G NG + + ++S +L F ++ G
Sbjct: 892 IPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQ--------QVSDHSL-----FGLDRYTG 938
Query: 1000 HVIVARSLPP--ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ RS E+E +L I D GN++ + + V VK V + ++
Sbjct: 939 QIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVMVKLVEPKEAFAASDLQSSAKDDE 998
Query: 1058 QYTRRVLGKVD-ATDADFGQNANLTYFIQPSDT-DLPFEISPLTG---VLSVNGELDRET 1112
++ A DAD G+ + Y + +D L + G +L V LDRET
Sbjct: 999 DMLAGARFQLKGAQDADSGRFSVQHYKLSQNDHFRLEVKDRGKDGKIPILVVQKSLDRET 1058
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ L + A D G D+NDN+P
Sbjct: 1059 AGSHSLVLTALDGGKPPKSGEMNILINVL-DINDNAP----------------------- 1094
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
V VY + EN IGTTV +V A D D NG ++YS NQ L L +
Sbjct: 1095 ---VFSKDVYSVMLHENTLIGTTVIQVNATDAD--DGPNGEVVYSFSNSMNQNVLDLFDI 1149
Query: 1233 SSTA--ILMVTVADVPD------EVEMSDK---PVFISRYYELEIEE-NVNAP-VELVSL 1279
+ I + D + EVE SDK P+ + ++I + N NAP +E+ S
Sbjct: 1150 NEITGEITVKGPIDYEENERYEIEVEASDKGFVPLKTEKTVIIDITDVNDNAPEIEVTSF 1209
Query: 1280 NL---TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ + + + +N+ D+ I + N + + + +P + K + ++ ++
Sbjct: 1210 SSFIPEDSRPGTTVAHISVNDLDSGINGKVICTISNDSPFAL-TPSLKDK-MFSLVTKSA 1267
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ R+ + + A+D + + + V + DVNDN P+F+
Sbjct: 1268 LDREQRD-KYDLTITAKDAGQLSLSSEKTITVVVSDVNDNRPEFS 1311
Score = 54.4 bits (125), Expect = 2e-05
Identities = 159/823 (19%), Positives = 310/823 (37%), Gaps = 65/823 (7%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+ G Q S L+V++ + D NDN+P F Y + + E P G
Sbjct: 96 VDGGKPQRSGTLNVSIIVLDNNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGAN 155
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGH---FALESSHKPVLLLR- 185
+ T+ +++ +D + N N ++ + ++ +E+S K R
Sbjct: 156 GEIEYSLSKTLVRNV--YDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTPPFRS 213
Query: 186 ------KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
KV+D + + ++ I D+D GV + + S
Sbjct: 214 RCRVIVKVIDVKSSRNRSDITNTVPEDSKPGTVI--SLISVSDKDSGVNGKIISRITSDV 271
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+L N + K LD E + + + +QA P + +++++ D+
Sbjct: 272 PFELKPSYKENTYSIVTKAF-LDRE---MTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDI 327
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY---QLDDPKGAFSIDP 356
NDN P F + +VEN G S+ V ATD D EN +Y +L+D +++
Sbjct: 328 NDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIARLNDVTSFLNVNS 387
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFADSQRIAKWRRQPLETNAPLE 415
+G ++ D E + + +V A ++ +PS+ + I NAP+
Sbjct: 388 ENGQISALKS--FDFETLKTFQFQVVASDSGSPSLSSNVTVNVFIL-----DQNDNAPV- 439
Query: 416 KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV 475
++P E +E + + VT + A D + + L+ S+
Sbjct: 440 ---ILYPVSSNGSAEGVEEIPRNVNA--GHLVTKVRAYDADIGYNGWLLFSLQQVSD--- 491
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP-NTGTVSVAESPILEGRHAL 534
++ G+ + V P L + + + L +T+ P +G + + +L+
Sbjct: 492 HSLFGEDRKV-PFLVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDII-IDVLDVNDNS 549
Query: 535 FVEASDQPANPSERRYSLAVVTIEV--TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
V A + ++ + + V I++ T +G +I G + + + I T+
Sbjct: 550 PVFAKELYSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSKLMNVFDIDTNT 609
Query: 593 GQIRVNDAFE-QNDVSYDL-LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL 650
G+IRV + + S++L + ++ ++S +I+V+D N P + E +
Sbjct: 610 GEIRVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVID--INDNAP--EIEVTSF 665
Query: 651 QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG 710
+ TV ++ V+D L G + +I +KE+S + NM ++
Sbjct: 666 SSSIKEDSKLGTTVALISVSD----LDSGINGKVICSLKEDSP-FNLSPSLQNNMYAVVT 720
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMT---VIAEFNKGVIS- 766
+ I ++ D+T + T T+K + DV + + + + V
Sbjct: 721 R--SQLDREIVSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTEN 778
Query: 767 ---GAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN--SKIGTEIKMDNIIKATDADEGT 821
GA ++ V DEN+N + H E + N S + + +I D T
Sbjct: 779 NSPGASVFSVKASDCDENNNAMITYHIRRERTLDANFASFLNINSETGDIFALKSFDFET 838
Query: 822 NALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLS 864
F + + + N V FI D D I+Y +S
Sbjct: 839 LKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVS 881
Score = 51.2 bits (117), Expect = 2e-04
Identities = 64/291 (21%), Positives = 114/291 (39%), Gaps = 19/291 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--API 124
L + G S +++ + + D+NDN P+F Y V + E T G A
Sbjct: 1066 LTALDGGKPPKSGEMNILINVLDINDNAPVFSKDVYSVMLHENTLIGTTVIQVNATDADD 1125
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPV 181
GP+ + + + + FD ++ T + Y N+ +E+S K
Sbjct: 1126 GPNGEVVYSFSNSMNQ-NVLDLFDINEITGEITVKGPIDYE---ENERYEIEVEASDKGF 1181
Query: 182 LLLRK----VLDY-DAGDKEFQLVIMASGKRIHKEILFPEPI-HAIDQDLGVGATLRYEL 235
+ L+ ++D D D ++ + + I ++ + H DL G +
Sbjct: 1182 VPLKTEKTVIIDITDVNDNAPEIEVTSFSSFIPEDSRPGTTVAHISVNDLDSGINGKVIC 1241
Query: 236 ISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
ND S+ +F L + LD E Q + + L + A +++ + +
Sbjct: 1242 TISNDSPFALTPSLKDKMFSLVTKSALDRE---QRDKYDLTITAKDAGQLSLSSEKTITV 1298
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ D+NDN PEF + Y I E G SV V A D+D +N +Y +
Sbjct: 1299 VVSDVNDNRPEFSLSPYTFYISEANQPGTSVFSVKAFDRDDNDNAHVSYHI 1349
Score = 48.0 bits (109), Expect = 0.002
Identities = 38/124 (30%), Positives = 50/124 (40%), Gaps = 4/124 (3%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-- 1088
V V + DVNDH P F +T F + E A D D G N+ TY + +D
Sbjct: 1 VVVEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDHF 60
Query: 1089 -TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
++ T L + LDRE +K+ L V A D G D NDN
Sbjct: 61 GIEMSQSDEEKTPFLVLKQSLDREKSNKHSLVVTAVDGG-KPQRSGTLNVSIIVLDNNDN 119
Query: 1148 SPKF 1151
P+F
Sbjct: 120 IPRF 123
Score = 47.6 bits (108), Expect = 0.003
Identities = 46/156 (29%), Positives = 66/156 (42%), Gaps = 21/156 (13%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
R + N +++S G +F K D + TF QV AS +P ++
Sbjct: 807 RERTLDANFASFLNINSETGDIFALKSFDFET-----LKTFQFQVVASDSGSPSLSSNVT 861
Query: 292 VEIELLDLNDNLPEFEVDFYNISI------VENLPN----GFSVLQVMATDKDQGENG-- 339
V + +LD NDN P V Y +S VE +P G V +V A D D G NG
Sbjct: 862 VNVFILDQNDNAP---VILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWL 918
Query: 340 EFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAH 374
F+ Q F +D +G + T+R+ T D H
Sbjct: 919 LFSLQQVSDHSLFGLDRYTGQIRTLRSFTETDEAEH 954
Score = 47.2 bits (107), Expect = 0.003
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 12/111 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F I E GT++ + A D D N + Y + P +KLS+ + IN
Sbjct: 1317 FYISEANQPGTSVFSVKAFDRDDNDNAHVSYHILRDGS-PENKLSS-------FLSINSE 1368
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPV 1044
G ++ +S E++ F+ + A D G+ L+ N++V+VF+ D ND+ PV
Sbjct: 1369 TGDILALKSFDFEAQKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPV 1419
Score = 39.9 bits (89), Expect = 0.53
Identities = 59/240 (24%), Positives = 95/240 (39%), Gaps = 27/240 (11%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL------TIPLTVP 135
+V + I DVNDN P T + + E + G + + + TI P
Sbjct: 1189 TVIIDITDVNDNAPEIEVTSFSSFIPEDSRPGTTVAHISVNDLDSGINGKVICTISNDSP 1248
Query: 136 RGLTIFKDIRAFD---RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
LT + F + + D + ++ D G +L SS K + ++ V D +
Sbjct: 1249 FALTPSLKDKMFSLVTKSALDREQRDKYDLTITAKDAGQLSL-SSEKTITVV--VSDVND 1305
Query: 193 GDKEFQL---VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN--DRKLFSLD 247
EF L S +F + A D+D A + Y ++ + KL S
Sbjct: 1306 NRPEFSLSPYTFYISEANQPGTSVFS--VKAFDRDDNDNAHVSYHILRDGSPENKLSSFL 1363
Query: 248 SVN---GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+N G + K D +A+ TF QV AS +P ++ V++ +LD NDN P
Sbjct: 1364 SINSETGDILALKSFDFEAQ-----KTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAP 1418
Score = 39.9 bits (89), Expect = 0.53
Identities = 33/111 (29%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + V + D NDN P F S Y F + + GT + VKA D D N V Y
Sbjct: 1290 LSSEKTITVVVSDVNDNRPEFSLSP-YTFYISEANQPGTSVFSVKAFDRDDNDNAHVSYH 1348
Query: 499 LQR--TSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPS 546
+ R + ++S IN TG + +S E + F + +PS
Sbjct: 1349 ILRDGSPENKLSSFLSINSETGDILALKSFDFEAQKTFQFQVVASDSGSPS 1399
Score = 36.7 bits (81), Expect = 4.9
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P S T + + V D D + DK Y++EI ENV + ++ + E
Sbjct: 99 GKPQRSGTLNVSIIVLDNNDNIPRFDKDT-----YQIEISENVPVGRTVTKVSAIDQDEG 153
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y + ++ F ++P NG + L D E +TY++ + A
Sbjct: 154 ANGEIEYSLSKTLVRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEA 203
>UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 4639
Score = 140 bits (338), Expect = 4e-31
Identities = 137/482 (28%), Positives = 218/482 (45%), Gaps = 60/482 (12%)
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + + I+ G I G +VT+ + D ND P+F+ ++ + E ++
Sbjct: 630 PLDRETAAQHILD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFNVSVNEIERL 686
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMY 861
GT + ATD D G N+ Y++ +E F ++ TG + + LDRE + Y
Sbjct: 687 GTVFLT---VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS-VAKQLDRETRDQY 742
Query: 862 KLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIH-RETKLNGTAGFTI 918
L+++A+D G L+S + I +GD NDN P + +++ +R+ E +N T G +
Sbjct: 743 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP----VIQDAVIRVSLSEVVVNVTDGGSP 798
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+K + +DV P N+ ++++ A N Q+ +E +
Sbjct: 799 A-LKSRAMVVIDVTPK------PRNLTYDVSVLEGEA-------NVQVMDLKPAESHFNV 844
Query: 979 SKLSADALEVK-RYFVINERHGHV-IVARSLPPESEFRLNISALDGGNLNDNISVRVFVK 1036
S + + F IN + V ++ L+IS +GG + + V V V
Sbjct: 845 SGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVL 904
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
D+ND P+F+ +N +V E + V V ATD D G N+ LTY I + + F I+
Sbjct: 905 DINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSIN 964
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
TG +SV +LDRET D+Y LTV+A+D G D NDN P
Sbjct: 965 NKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNSTTAVAIQVGDANDNPP------- 1016
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
V+ V + ++ E A I T VA V A+D D IG NG ++Y
Sbjct: 1017 -------------------VIQDAVIQVSLSETAEIDTPVATVIASDKD-IG-ANGRLMY 1055
Query: 1217 SL 1218
S+
Sbjct: 1056 SI 1057
Score = 126 bits (305), Expect = 4e-27
Identities = 174/687 (25%), Positives = 289/687 (42%), Gaps = 73/687 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + +GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 693 VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 747
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V+ D G
Sbjct: 748 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE----------VVVNVTDGGS 797
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG---TF 394
+ + + P+ LT + +VL+ EA+ + M + E++ +V G TF
Sbjct: 798 PALKSRAMV----VIDVTPKPRNLTY-DVSVLEGEANVQV-MDLKPAESHFNVSGGNFTF 851
Query: 395 ADSQ-RIAKWRRQPLETNA-PLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
DS + L + PL++ T + TE + FV V V +LD
Sbjct: 852 FDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEG-----GTIKGFVKVTVNVLDI 906
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
ND P+F S + S+ ++GTV V A D D G N + Y + + F
Sbjct: 907 NDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGF---FS 962
Query: 513 INPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
IN TG +SVA+ E R + L V A D P S V I+V G + P
Sbjct: 963 INNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN---STTAVAIQV--GDANDNP-- 1015
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAVEERS-G 627
P A + + I T V + +D + + L++ E G F +++ S G
Sbjct: 1016 PVIQDAVIQVSLSETAEIDTPVATVIASD--KDIGANGRLMYSIESGAHGHFRIKDSSSG 1073
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
I++ LS YN+ V + + + ++ + A V V+DV K +
Sbjct: 1074 AISLAGMLS-YNQRNNYIVVVNVTDGGSPALKSRAMV-VIDVTP------KPRNLTYDVS 1125
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
V E A + + S + GN F ++ + + G+ PLDRE
Sbjct: 1126 VLEGEANVQVMDL--KPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGST----PLDRE 1179
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
+ + I+ G I G +VT+ + D ND P+F+ ++ + E ++GT
Sbjct: 1180 TAAQHILD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFL 1236
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ ATD D G N+ Y++ +E F ++ TG + + LDRE + Y L+++
Sbjct: 1237 T---VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS-VAKQLDRETRDQYTLTVM 1292
Query: 867 ARDTG--GLSSEAELIIMIGDENDNKP 891
A+D G L+S + I +GD NDN P
Sbjct: 1293 AQDGGEPPLNSTTAVAIQVGDANDNPP 1319
Score = 124 bits (300), Expect = 1e-26
Identities = 160/662 (24%), Positives = 280/662 (42%), Gaps = 60/662 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + +GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 1541 VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 1595
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 1596 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGA 1655
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVY-----AKETNPSV 390
NG Y ++ G F I D SG +++ ++ + + + V A ++ V
Sbjct: 1656 NGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV 1715
Query: 391 VGTFADSQRIAKWRRQPLETNAPLE----KTTYVFPDKVGTKTENIEYY---------DE 437
V R + LE A ++ KT + K + +Y +
Sbjct: 1716 VIDVTPKPRNLTYDVSVLEGEANVQVMDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEP 1775
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L S V + + DANDN PV + + S+ A + T + V A D D+G NG ++Y
Sbjct: 1776 PLNSTTAVAIQVGDANDNPPV-IQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMY 1834
Query: 498 DLQRTSNLTITSPFKI-NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
++ ++ F+I + ++G +S+A R+ V + S S A+V
Sbjct: 1835 SIESGAH----GHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGG-SPALKSRAMVV 1889
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+VT + D+ G +NV + + V F + ++ +
Sbjct: 1890 IDVTPKPRNLTYDVSVLEGE-------ANVQV---MDLKPVVSHFNVSGGNFTFFN--SS 1937
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G F++ + + L R + + ++L E + TV+V+D+NDE +
Sbjct: 1938 GSMFSI-NGNNLRVGSTPLDRETAAQHVLD-ISLTEGGTIKGFVKVTVNVLDINDETPLF 1995
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAE 734
SP F+V N +G +F T +S+ G+ N + + IA + +
Sbjct: 1996 ----QSP-SFNVSVNEI-ERLGTVFLT-VSATDGDAGANSALTYSIAAGNEEGFFSINNK 2048
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I K LDRE RD Y +TV+A+ + G V I + D NDNPPV + A
Sbjct: 2049 TGAISVAKQLDRETRDQYTLTVMAQ-DGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRV 2107
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF-IGDSL 853
+ E ++I T + + A+D D G N MY++ F + +++ ++ + +S
Sbjct: 2108 SLSETAEIDTPVA---TVIASDKDIGANGRLMYSIESGAHGHFQIKDSSKCRRYTVFNSF 2164
Query: 854 DR 855
DR
Sbjct: 2165 DR 2166
Score = 111 bits (267), Expect = 1e-22
Identities = 120/461 (26%), Positives = 200/461 (43%), Gaps = 42/461 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ FV V V +LD ND P+F S + S+ ++GTV V A D D G N + Y
Sbjct: 3834 IKGFVKVTVNVLDINDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 3892
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + F IN TG +SVA+ E R + L V A D P S V
Sbjct: 3893 IAAGNEEGF---FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN---STTAVA 3946
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+V G + P P A + I T V + +D + + L++ E
Sbjct: 3947 IQV--GDANDNP--PVIQDAVIRVSLSETAAIDTPVATVIASD--KDIGANGRLMYSIES 4000
Query: 617 GVP--FAVEERS-GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
G F +++ S G I++ LS YN+ V + + + ++ + A V V+DV
Sbjct: 4001 GAHGHFQIKDSSSGAISLAGMLS-YNQRNNYIVVVNVTDGGSPALKSRAMV-VIDVTP-- 4056
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + V E A Q+ + + N +G + + +I
Sbjct: 4057 ----KPRNLTYDVSVLEGEANV---QVMDLKPAESHFNASGGTFAFFGSSGSM---FSIN 4106
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
PLDRE + + + I+ G++ G +++VT+ + D ND P F+ ++
Sbjct: 4107 GTNLRVGSTPLDRETAEEHVLD-ISLTEGGIVKG--LFKVTVNVLDINDETPSFQSPSFN 4163
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDS 852
+ E ++GT + ATD+D G N+ Y++ +E +F ++ T + +
Sbjct: 4164 VSVNEIERLGTVFLT---VSATDSDAGANSALTYSIAAGNEEGVFSINNKTAAIS-VAKQ 4219
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LDRE + +Y L+++A+D G L+ A + I +GD NDN P
Sbjct: 4220 LDRETRDLYMLTVMAQDGGEPSLNRTAAVPIQVGDANDNPP 4260
Score = 109 bits (261), Expect = 8e-22
Identities = 162/675 (24%), Positives = 282/675 (41%), Gaps = 67/675 (9%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E Q +L + ++ +K +V + +LD+ND P
Sbjct: 1463 SMFSINGTNLRVGSTPLDRETAAQ---HILDISLTE-GGTIK-GFVKVTVNVLDINDETP 1517
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F+ +N+S+ E G L V ATD D G N TY + + +G FSI+ ++G ++
Sbjct: 1518 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS 1577
Query: 363 VRNQTVLDREAHSSLRMKVYAKETN-PSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
V Q LDRE + V A++ P + T A + ++ P + + +
Sbjct: 1578 VAKQ--LDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 1635
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTL-------LDANDNNPVFVP-SNLYEFSMKSNA 473
+ T + D+ + + + ++ D++ + + + ++ ++N
Sbjct: 1636 TAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNY 1695
Query: 474 KVGTVIGKVKAVDPDLGQNGMVLYDLQ-RTSNLTI-TSPFKINPN-------TGTVSVAE 524
V V+ P L MV+ D+ + NLT S + N TG +SVA+
Sbjct: 1696 IV--VVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVLEGEANVQVMDLKTGAISVAK 1753
Query: 525 SPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
E R + L V A D P S V I+V G + P P A +
Sbjct: 1754 QLDRETRDQYTLTVMAQDGGEPPLN---STTAVAIQV--GDANDNP--PVIQDAVIRVSL 1806
Query: 583 GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAVEERS-GVITVVDDLSRYN 639
I T V + +D + + L++ E G F +++ S G I++ LS YN
Sbjct: 1807 SETAAIDTPVATVIASD--KDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLS-YN 1863
Query: 640 RPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
+ V + + + ++ + A V V+DV K + V E A +
Sbjct: 1864 QRNNYIVVVNVTDGGSPALKSRAMV-VIDVTP------KPRNLTYDVSVLEGEANVQVMD 1916
Query: 700 IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ + S + GN F ++ +I + PLDRE + + I+
Sbjct: 1917 L--KPVVSHFNVSGGNFTFFNSSGSM----FSINGNNLRVGSTPLDRETAAQHVLD-ISL 1969
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
G I G +VT+ + D ND P+F+ ++ + E ++GT + ATD D
Sbjct: 1970 TEGGTIKG--FVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLT---VSATDGDA 2024
Query: 820 GTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE 876
G N+ Y++ +E F ++ TG + + LDRE + Y L+++A+D G L+S
Sbjct: 2025 GANSALTYSIAAGNEEGFFSINNKTGAIS-VAKQLDRETRDQYTLTVMAQDGGEPPLNST 2083
Query: 877 AELIIMIGDENDNKP 891
+ I +GD NDN P
Sbjct: 2084 TAVAIQVGDANDNPP 2098
Score = 107 bits (258), Expect = 2e-21
Identities = 123/461 (26%), Positives = 198/461 (42%), Gaps = 42/461 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ FV V V +LD ND P+F S + S+ ++GTV V A D D G N + Y
Sbjct: 3531 IKGFVKVTVNVLDINDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 3589
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + F IN TG +SVA+ E R + L V A D P S V
Sbjct: 3590 IAVGNEEGF---FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN---STTAVA 3643
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+V G + P P A + + I T V + +D + + L++ E
Sbjct: 3644 IQV--GDANDNP--PVIQDAVIQVSLSETAEIDTPVATVIASD--KDIGANGRLMYSIES 3697
Query: 617 GVP--FAVEERS-GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
G F +++ S G I++ LS YN+ V + + + ++ + A V V+DV
Sbjct: 3698 GAHGHFRIKDSSSGAISLAGMLS-YNQRNNYIVVVNVTDGGSPALKSRAMV-VIDVTP-- 3753
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + V E A + + + S + GN F ++ +I
Sbjct: 3754 ----KPRNLTYDVSVLEGEANVQVMDL--KPVVSHFNVSGGNFTFFNSSGSM----FSIN 3803
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ PLDRE + + I+ G I G +VT+ + D ND P+F+ ++
Sbjct: 3804 GNNLSVGSTPLDRETAAQHVLD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFN 3860
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDS 852
+ E ++GT + ATD D G N+ Y++ +E F ++ TG + +
Sbjct: 3861 VSVNEIERLGTVFLT---VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS-VAKQ 3916
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LDRE + Y L+++A+D G L+S + I +GD NDN P
Sbjct: 3917 LDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 3957
Score = 107 bits (256), Expect = 3e-21
Identities = 123/461 (26%), Positives = 197/461 (42%), Gaps = 42/461 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ FV V V +LD ND P+F S + S+ ++GTV V A D D G N + Y
Sbjct: 1196 IKGFVKVTVNVLDINDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 1254
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + F IN TG +SVA+ E R + L V A D P S V
Sbjct: 1255 IAAGNEEGF---FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN---STTAVA 1308
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+V G + P P A + I T V + +D + + L++ E
Sbjct: 1309 IQV--GDANDNP--PVIQDAVIRVSLSETAEIDTPVATVIASD--KDIGANGRLMYSIES 1362
Query: 617 GVP--FAVEERS-GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
G F +++ S G I++ LS YN+ V + + + ++ + A V V+DV
Sbjct: 1363 GAHGHFQIKDSSSGAISLAGMLS-YNQRNNYIVVVNVTDGGSPALKSRAMV-VIDVKP-- 1418
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + V E A + + S + GN F ++ + +
Sbjct: 1419 ----KPRNLTYDVSVLEGEANVQVMDL--KPAESHFNVSGGNFTFFDSSGSMFSINGTNL 1472
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G+ PLDRE + + I+ G I G +VT+ + D ND P+F+ ++
Sbjct: 1473 RVGST----PLDRETAAQHILD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFN 1525
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDS 852
+ E ++GT + ATD D G N+ Y++ +E F ++ TG + +
Sbjct: 1526 VSVNEIERLGTVFLT---VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS-VAKQ 1581
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LDRE + Y L+++A+D G L+S + I +GD NDN P
Sbjct: 1582 LDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 1622
Score = 97.1 bits (231), Expect = 3e-18
Identities = 90/322 (27%), Positives = 144/322 (44%), Gaps = 40/322 (12%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 1489 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 1548
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 1549 GANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 1607
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 1608 TAVAIQVGDANDNPP--------------------------VIQDAVIRVSLSETAAIDT 1641
Query: 1195 TVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
VA V A+D D IG NG ++YS+ + + + SS AI + + + + +
Sbjct: 1642 PVATVIASDKD-IG-ANGRLMYSI-ESGAHGHFQIKDSSSGAISLAGM------LSYNQR 1692
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGT 1314
+I + +V +++T N +L E + +++ V+D + G
Sbjct: 1693 NNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVL-EGEANVQ---VMDLKTGA 1748
Query: 1315 LYLVRSPDREVKDTYEVIVRAE 1336
+ + + DRE +D Y + V A+
Sbjct: 1749 ISVAKQLDRETRDQYTLTVMAQ 1770
Score = 94.3 bits (224), Expect = 2e-17
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 29/204 (14%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 1186 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 1245
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 1246 GANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 1304
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 1305 TAVAIQVGDANDNPP--------------------------VIQDAVIRVSLSETAEIDT 1338
Query: 1195 TVAKVFANDTDFIGNGNGLILYSL 1218
VA V A+D D IG NG ++YS+
Sbjct: 1339 PVATVIASDKD-IG-ANGRLMYSI 1360
Score = 94.3 bits (224), Expect = 2e-17
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 29/204 (14%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 1965 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 2024
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 2025 GANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 2083
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 2084 TAVAIQVGDANDNPP--------------------------VIQDAVIRVSLSETAEIDT 2117
Query: 1195 TVAKVFANDTDFIGNGNGLILYSL 1218
VA V A+D D IG NG ++YS+
Sbjct: 2118 PVATVIASDKD-IG-ANGRLMYSI 2139
Score = 94.3 bits (224), Expect = 2e-17
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 29/204 (14%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 3824 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 3883
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 3884 GANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 3942
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 3943 TAVAIQVGDANDNPP--------------------------VIQDAVIRVSLSETAAIDT 3976
Query: 1195 TVAKVFANDTDFIGNGNGLILYSL 1218
VA V A+D D IG NG ++YS+
Sbjct: 3977 PVATVIASDKD-IG-ANGRLMYSI 3998
Score = 93.5 bits (222), Expect = 4e-17
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 29/204 (14%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 2963 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 3022
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 3023 GANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 3081
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 3082 TAVAIQVGDANDNPP--------------------------VIQDAVIQVSLSETAEIDT 3115
Query: 1195 TVAKVFANDTDFIGNGNGLILYSL 1218
VA V A+D D IG NG ++YS+
Sbjct: 3116 PVATVIASDKD-IG-ANGRLMYSI 3137
Score = 93.5 bits (222), Expect = 4e-17
Identities = 70/204 (34%), Positives = 97/204 (47%), Gaps = 29/204 (14%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
L+IS +GG + + V V V D+ND P+F+ +N +V E + V V ATD D
Sbjct: 3521 LDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDA 3580
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G N+ LTY I + + F I+ TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 3581 GANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNST 3639
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P V+ V + ++ E A I T
Sbjct: 3640 TAVAIQVGDANDNPP--------------------------VIQDAVIQVSLSETAEIDT 3673
Query: 1195 TVAKVFANDTDFIGNGNGLILYSL 1218
VA V A+D D IG NG ++YS+
Sbjct: 3674 PVATVIASDKD-IG-ANGRLMYSI 3695
Score = 89.0 bits (211), Expect = 9e-16
Identities = 120/490 (24%), Positives = 213/490 (43%), Gaps = 49/490 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + DANDN PV + + + S+ A++ T + V A D D+G NG ++Y
Sbjct: 998 LNSTTAVAIQVGDANDNPPV-IQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYS 1056
Query: 499 LQRTSNLTITSPFKI-NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
++ ++ F+I + ++G +S+A R+ V + S S A+V I
Sbjct: 1057 IESGAH----GHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGG-SPALKSRAMVVI 1111
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE- 616
+VT + D+ G +NV + + + A +VS ++
Sbjct: 1112 DVTPKPRNLTYDVSVLEGE-------ANVQV------MDLKPAESHFNVSGGNFTFFDSS 1158
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G F++ + + L R + + ++L E + TV+V+D+NDE +
Sbjct: 1159 GSMFSING-TNLRVGSTPLDRETAAQHILD-ISLTEGGTIKGFVKVTVNVLDINDETPLF 1216
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAE 734
SP F+V N +G +F T +S+ G+ N + + IA + +
Sbjct: 1217 ----QSPS-FNVSVNEI-ERLGTVFLT-VSATDGDAGANSALTYSIAAGNEEGFFSINNK 1269
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I K LDRE RD Y +TV+A+ + G V I + D NDNPPV + A
Sbjct: 1270 TGAISVAKQLDRETRDQYTLTVMAQ-DGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRV 1328
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV-DENTGVVKFIGDSL 853
+ E ++I T + + A+D D G N MY++ F + D ++G + G L
Sbjct: 1329 SLSETAEIDTPVA---TVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAG-ML 1384
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
++ Y + + D G + ++ +++I D KP+ + + V L G
Sbjct: 1385 SYNQRNNYIVVVNVTDGGSPALKSRAMVVI----DVKPKPRNLTYDVSV-------LEGE 1433
Query: 914 AGFTIIEVKP 923
A ++++KP
Sbjct: 1434 ANVQVMDLKP 1443
Score = 88.6 bits (210), Expect = 1e-15
Identities = 70/207 (33%), Positives = 96/207 (46%), Gaps = 29/207 (14%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
E L+IS +GG + V V V D+ND P F+ +N +V E + V V ATD
Sbjct: 4124 EHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTVFLTVSATD 4183
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
+D G N+ LTY I + + F I+ T +SV +LDRET D Y+LTV+A+D G
Sbjct: 4184 SDAGANSALTYSIAAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMAQDGG-EPSL 4242
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
D NDN P V+ V + ++ E A
Sbjct: 4243 NRTAAVPIQVGDANDNPP--------------------------VIQDAVIRVSLSETAA 4276
Query: 1192 IGTTVAKVFANDTDFIGNGNGLILYSL 1218
I T VA V A+D D IG NG ++YS+
Sbjct: 4277 IDTPVATVIASDKD-IG-ANGRLMYSI 4301
Score = 87.8 bits (208), Expect = 2e-15
Identities = 110/449 (24%), Positives = 195/449 (43%), Gaps = 36/449 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + DANDN PV + + + S+ A++ T + V A D D+G NG ++Y
Sbjct: 3636 LNSTTAVAIQVGDANDNPPV-IQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYS 3694
Query: 499 LQRTSNLTITSPFKI-NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
++ ++ F+I + ++G +S+A R+ V + S S A+V I
Sbjct: 3695 IESGAH----GHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGG-SPALKSRAMVVI 3749
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+VT + D+ G +NV + + V F + ++ + G
Sbjct: 3750 DVTPKPRNLTYDVSVLEGE-------ANVQV---MDLKPVVSHFNVSGGNFTFFNS--SG 3797
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F++ + + L R + + ++L E + TV+V+D+NDE +
Sbjct: 3798 SMFSINGNNLSVGSTP-LDRETAAQHVLD-ISLTEGGTIKGFVKVTVNVLDINDETPLF- 3854
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAED 735
SP F+V N +G +F T +S+ G+ N + + IA + +
Sbjct: 3855 ---QSPS-FNVSVNEI-ERLGTVFLT-VSATDGDAGANSALTYSIAAGNEEGFFSINNKT 3908
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I K LDRE RD Y +TV+A+ + G V I + D NDNPPV + A
Sbjct: 3909 GAISVAKQLDRETRDQYTLTVMAQ-DGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVS 3967
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV-DENTGVVKFIGDSLD 854
+ E + I T + + A+D D G N MY++ F + D ++G + G L
Sbjct: 3968 LSETAAIDTPVA---TVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAG-MLS 4023
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ Y + + D G + ++ +++I
Sbjct: 4024 YNQRNNYIVVVNVTDGGSPALKSRAMVVI 4052
Score = 78.2 bits (184), Expect = 2e-12
Identities = 71/256 (27%), Positives = 117/256 (45%), Gaps = 17/256 (6%)
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
++L E + + TV+V+D+NDE SP F+V N +G +F T ++
Sbjct: 4129 ISLTEGGIVKGLFKVTVNVLDINDET----PSFQSPS-FNVSVNEI-ERLGTVFLTVSAT 4182
Query: 708 IYGNGTGN-VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
G + + + IA + + I K LDRE RD+Y +TV+A+ + G S
Sbjct: 4183 DSDAGANSALTYSIAAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMAQ-DGGEPS 4241
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
V I + D NDNPPV + A + E + I T + + A+D D G N M
Sbjct: 4242 LNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVAT---VIASDKDIGANGRLM 4298
Query: 827 YTLFGEGKEMFDV-DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG- 884
Y++ F + D ++G + G L +++ Y + + D G L+ E+ I++I
Sbjct: 4299 YSIESGAHGHFQIKDSSSGAISVAG-RLSYKQRNNYSVVVKVTDGGSLALESRAIVLIDV 4357
Query: 885 ---DENDNKPEFNQIE 897
EN N P F ++
Sbjct: 4358 TPTTENRNAPVFASVQ 4373
Score = 77.8 bits (183), Expect = 2e-12
Identities = 118/500 (23%), Positives = 209/500 (41%), Gaps = 51/500 (10%)
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
++L E + TV+V+D+NDE + SP F+V N +G +F T +S+
Sbjct: 2965 ISLTEGGTIKGFVKVTVNVLDINDETPLF----QSPS-FNVSVNEI-ERLGTVFLT-VSA 3017
Query: 708 IYGNGTGN--VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
G+ N + + IA + + G I K LDRE RD Y +TV+A+ + G
Sbjct: 3018 TDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQ-DGGEP 3076
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
V I + D NDNPPV + A + + E ++I T + + A+D D G N
Sbjct: 3077 PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVA---TVIASDKDIGANGRL 3133
Query: 826 MYTLFGEGKEMFDV-DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
MY++ F + D ++G + G L ++ Y + + D G + ++ I++I
Sbjct: 3134 MYSIESGALGHFQIKDWSSGAISLAG-MLSYNQRNNYIVVVNVTDGGSPALKSRAIVVI- 3191
Query: 885 DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP-KNKFALD------VDQLGPL 937
D P+ + H + L G A ++++KP ++ F + D G +
Sbjct: 3192 ---DVTPKPRNL-------THDVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSM 3241
Query: 938 FLI-PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP-SKLSADALEVKRYFVIN 995
F I N+ +G+T LD ++ + I K++ + L++ +
Sbjct: 3242 FSINGTNLRVGST-----PLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLF 3296
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK-----KTWY 1050
+ + + L +SA D G+ N ++ + N+ V + +
Sbjct: 3297 QSPSFNVSVNEIERLGTVFLTVSATD-GDAGANSALTYSIAAGNEEGLVERTILKYSNLF 3355
Query: 1051 NFNVEEAQYTRRV---LGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSVNG 1106
+F+ T + + V A+D D G N L Y I+ S F+I +G +S+ G
Sbjct: 3356 DFSDLFCSQTAEIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKDSSSGAISLAG 3414
Query: 1107 ELDRETEDKYILTVVARDNG 1126
L + YI+ V D G
Sbjct: 3415 MLSYNQRNNYIVVVNVTDGG 3434
Score = 74.9 bits (176), Expect = 2e-11
Identities = 48/152 (31%), Positives = 78/152 (51%), Gaps = 10/152 (6%)
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + + I+ G I G +VT+ + D ND P+F+ ++ + E ++
Sbjct: 2952 PLDRETAAQHILD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFNVSVNEIERL 3008
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
GT + ATD D G N+ Y++ G + F ++ TG + + LDRE + Y
Sbjct: 3009 GTVFLT---VSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAIS-VAKQLDRETRDQY 3064
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
L+++A+D G L+S + I +GD NDN P
Sbjct: 3065 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 3096
Score = 74.9 bits (176), Expect = 2e-11
Identities = 48/152 (31%), Positives = 78/152 (51%), Gaps = 10/152 (6%)
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + + I+ G I G +VT+ + D ND P+F+ ++ + E ++
Sbjct: 3510 PLDRETAAQHILD-ISLTEGGTIKG--FVKVTVNVLDINDETPLFQSPSFNVSVNEIERL 3566
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
GT + ATD D G N+ Y++ G + F ++ TG + + LDRE + Y
Sbjct: 3567 GTVFLT---VSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAIS-VAKQLDRETRDQY 3622
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
L+++A+D G L+S + I +GD NDN P
Sbjct: 3623 TLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 3654
Score = 73.7 bits (173), Expect = 3e-11
Identities = 103/402 (25%), Positives = 165/402 (41%), Gaps = 38/402 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ FV V V +LD ND P+F S + S+ ++GTV V A D D G N + Y
Sbjct: 2973 IKGFVKVTVNVLDINDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 3031
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ + F IN TG +SVA+ E R + L V A D P S V
Sbjct: 3032 IAVGNE---EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLN---STTAVA 3085
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+V G + P P A + + I T V + +D + + L++ E
Sbjct: 3086 IQV--GDANDNP--PVIQDAVIQVSLSETAEIDTPVATVIASD--KDIGANGRLMYSIES 3139
Query: 617 GV--PFAVEE-RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
G F +++ SG I++ LS YN+ V + + + ++ + A V V+DV +
Sbjct: 3140 GALGHFQIKDWSSGAISLAGMLS-YNQRNNYIVVVNVTDGGSPALKSRAIV-VIDVTPKP 3197
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
L H V E A + + S + GN F ++ + +
Sbjct: 3198 RNL---THD---VSVLEGEANVQVMDL--KPAESHFNVSGGNFTFFDSSGSMFSINGTNL 3249
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G+ PLDRE + I+ G I G +VT+ + D ND P+F+ ++
Sbjct: 3250 RVGS----TPLDRETA-AQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFN 3302
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ E ++GT + ATD D G N+ Y++ +E
Sbjct: 3303 VSVNEIERLGTVFL---TVSATDGDAGANSALTYSIAAGNEE 3341
Score = 72.1 bits (169), Expect = 1e-10
Identities = 47/166 (28%), Positives = 80/166 (48%), Gaps = 7/166 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + +GN+ +FS+++ ++ + K+LD + + ++L V
Sbjct: 4179 VSATDSDAGANSALTYSIAAGNEEGVFSINNKTAAISVAKQLDRETR-----DLYMLTVM 4233
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P A V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 4234 AQDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGA 4293
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKV 381
NG Y ++ G F I D SG ++V + + + S+ +KV
Sbjct: 4294 NGRLMYSIESGAHGHFQIKDSSSGAISVAGRLSYKQRNNYSVVVKV 4339
Score = 71.7 bits (168), Expect = 1e-10
Identities = 109/429 (25%), Positives = 174/429 (40%), Gaps = 59/429 (13%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 3845 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 3891
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S A + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 3892 SIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 3951
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
ND+ PV + ++ E + V A+D D G N L Y I+ S F+I
Sbjct: 3952 ANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKD 4010
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD- 1155
+G +S+ G L + YI+ V D G DV P+ +D
Sbjct: 4011 SSSGAISLAGMLSYNQRNNYIVVVNVTDGG----SPALKSRAMVVIDVTP-KPRNLTYDV 4065
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL 1215
+LE + +V ++ + A NA G T A ++ + F NG L +
Sbjct: 4066 SVLEGE------------ANVQVMDLKPAESHFNAS-GGTFAFFGSSGSMFSINGTNLRV 4112
Query: 1216 YSLP-QRKNQQNLGLP-SLSSTAI------LMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
S P R+ + L SL+ I + V V D+ DE P F E+
Sbjct: 4113 GSTPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNVSVNEI--- 4169
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
E + VS ++ N + Y I N+ + F I+ + + + + DRE +D
Sbjct: 4170 ERLGTVFLTVSATDSDAGANSALTYSIAAGNEEGV---FSINNKTAAISVAKQLDRETRD 4226
Query: 1328 TYEVIVRAE 1336
Y + V A+
Sbjct: 4227 LYMLTVMAQ 4235
Score = 71.3 bits (167), Expect = 2e-10
Identities = 65/239 (27%), Positives = 111/239 (46%), Gaps = 15/239 (6%)
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
++L E + TV+V+D+NDE + SP F+V N +G +F T +S+
Sbjct: 3523 ISLTEGGTIKGFVKVTVNVLDINDETPLF----QSPS-FNVSVNEI-ERLGTVFLT-VSA 3575
Query: 708 IYGNGTGN--VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
G+ N + + IA + + G I K LDRE RD Y +TV+A+ + G
Sbjct: 3576 TDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQ-DGGEP 3634
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
V I + D NDNPPV + A + + E ++I T + + A+D D G N
Sbjct: 3635 PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVA---TVIASDKDIGANGRL 3691
Query: 826 MYTLFGEGKEMFDV-DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
MY++ F + D ++G + G L ++ Y + + D G + ++ +++I
Sbjct: 3692 MYSIESGAHGHFRIKDSSSGAISLAG-MLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI 3749
Score = 68.5 bits (160), Expect = 1e-09
Identities = 43/148 (29%), Positives = 71/148 (47%), Gaps = 7/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + +GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 1238 VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 1292
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 1293 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGA 1352
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTV 363
NG Y ++ G F I D SG +++
Sbjct: 1353 NGRLMYSIESGAHGHFQIKDSSSGAISL 1380
Score = 68.5 bits (160), Expect = 1e-09
Identities = 99/425 (23%), Positives = 172/425 (40%), Gaps = 51/425 (12%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 3542 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 3588
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 3589 SIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 3648
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
ND+ PV + ++ E + V A+D D G N L Y I+ S F I
Sbjct: 3649 ANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFRIKD 3707
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
+G +S+ G L + YI+ V D G DV P+ +D
Sbjct: 3708 SSSGAISLAGMLSYNQRNNYIVVVNVTDGG----SPALKSRAMVVIDVTP-KPRNLTYD- 3761
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
+S E+ + + K + G ++ + F NGN L +
Sbjct: 3762 -----------VSVLEGEANVQVMDLKPVVSHFNVSGGNFTFFNSSGSMFSINGNNLSVG 3810
Query: 1217 SLP--QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELEIEENVNAP 1273
S P + Q++ SL+ + V + ++++D+ P+F S + + + E
Sbjct: 3811 STPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLG 3870
Query: 1274 VELVSLNLT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
++++ T + N + Y I N+ F I+ + G + + + DRE +D Y +
Sbjct: 3871 TVFLTVSATDGDAGANSALTYSIAAGNEEGF---FSINNKTGAISVAKQLDRETRDQYTL 3927
Query: 1332 IVRAE 1336
V A+
Sbjct: 3928 TVMAQ 3932
Score = 68.5 bits (160), Expect = 1e-09
Identities = 43/148 (29%), Positives = 71/148 (47%), Gaps = 7/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + +GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 3876 VSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 3930
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 3931 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGA 3990
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTV 363
NG Y ++ G F I D SG +++
Sbjct: 3991 NGRLMYSIESGAHGHFQIKDSSSGAISL 4018
Score = 68.1 bits (159), Expect = 2e-09
Identities = 61/210 (29%), Positives = 94/210 (44%), Gaps = 26/210 (12%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 1207 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 1253
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S A + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 1254 SIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 1313
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
ND+ PV + ++ E + V A+D D G N L Y I+ S F+I
Sbjct: 1314 ANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKD 1372
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+G +S+ G L + YI+ V D G
Sbjct: 1373 SSSGAISLAGMLSYNQRNNYIVVVNVTDGG 1402
Score = 68.1 bits (159), Expect = 2e-09
Identities = 61/210 (29%), Positives = 94/210 (44%), Gaps = 26/210 (12%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 1510 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 1556
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S A + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 1557 SIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 1616
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
ND+ PV + ++ E + V A+D D G N L Y I+ S F+I
Sbjct: 1617 ANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKD 1675
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+G +S+ G L + YI+ V D G
Sbjct: 1676 SSSGAISLAGMLSYNQRNNYIVVVNVTDGG 1705
Score = 66.9 bits (156), Expect = 4e-09
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 7/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 3573 VSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 3627
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 3628 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGA 3687
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTV 363
NG Y ++ G F I D SG +++
Sbjct: 3688 NGRLMYSIESGAHGHFRIKDSSSGAISL 3715
Score = 65.7 bits (153), Expect = 9e-09
Identities = 60/210 (28%), Positives = 92/210 (43%), Gaps = 26/210 (12%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 904 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 950
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 951 SIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 1010
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
ND+ PV + ++ E + V A+D D G N L Y I+ S F I
Sbjct: 1011 ANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFRIKD 1069
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+G +S+ G L + YI+ V D G
Sbjct: 1070 SSSGAISLAGMLSYNQRNNYIVVVNVTDGG 1099
Score = 65.7 bits (153), Expect = 9e-09
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 7/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + L Y + GN+ FS+++ G++ + K+LD + + + L V
Sbjct: 3015 VSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETR-----DQYTLTVM 3069
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + V I++ D NDN P + +S+ E V V+A+DKD G
Sbjct: 3070 AQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGA 3129
Query: 338 NGEFTYQLDD-PKGAFSI-DPRSGWLTV 363
NG Y ++ G F I D SG +++
Sbjct: 3130 NGRLMYSIESGALGHFQIKDWSSGAISL 3157
Score = 62.9 bits (146), Expect = 7e-08
Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 7/147 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D A + + ++SGN+ + FS+D V G + + K LD D + L + A
Sbjct: 2546 ATDADATTNAIITFVIVSGNEGEAFSIDKVTGDITISKPLDYDK----GPRVYTLNISAM 2601
Query: 280 QLNNPLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ-GE 337
+ L V I + D++D F Y I +N P G + QV A D D
Sbjct: 2602 NNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLGSLITQVHAKDMDSLNA 2661
Query: 338 NGEFT-YQLDDPKGAFSIDPRSGWLTV 363
E++ Y DP G F+I+ SG +TV
Sbjct: 2662 PVEYSIYPDSDPGGLFAINKTSGEVTV 2688
Score = 61.3 bits (142), Expect = 2e-07
Identities = 53/186 (28%), Positives = 82/186 (44%), Gaps = 19/186 (10%)
Query: 946 IGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
+GT + ++A D D+G N + Y S A + F IN + + VA+
Sbjct: 4172 LGTVFLTVSATDSDAGANSALTY-------------SIAAGNEEGVFSINNKTAAISVAK 4218
Query: 1006 SLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
L E+ + L + A DGG +LN +V + V D ND+ PV + ++ E
Sbjct: 4219 QLDRETRDLYMLTVMAQDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAID 4278
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSVNGELDRETEDKYILTV 1120
+ V A+D D G N L Y I+ S F+I +G +SV G L + + Y + V
Sbjct: 4279 TPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKDSSSGAISVAGRLSYKQRNNYSVVV 4337
Query: 1121 VARDNG 1126
D G
Sbjct: 4338 KVTDGG 4343
Score = 60.9 bits (141), Expect = 3e-07
Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 32/260 (12%)
Query: 150 DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASG---- 205
DK N + YSI SG GHF ++ S + L +L Y+ + +V + G
Sbjct: 3682 DKDIGANGRLMYSIESGAH-GHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA 3740
Query: 206 --KRIHKEI-LFPEP------IHAIDQDLGVGA-----TLRYELISGNDRKLF----SLD 247
R I + P+P + ++ + V + + +SG + F S+
Sbjct: 3741 LKSRAMVVIDVTPKPRNLTYDVSVLEGEANVQVMDLKPVVSHFNVSGGNFTFFNSSGSMF 3800
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
S+NG+ LD E Q VL + ++ +K +V + +LD+ND P F+
Sbjct: 3801 SINGNNLSVGSTPLDRETAAQ---HVLDISLTE-GGTIK-GFVKVTVNVLDINDETPLFQ 3855
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRN 365
+N+S+ E G L V ATD D G N TY + + +G FSI+ ++G ++V
Sbjct: 3856 SPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAK 3915
Query: 366 QTVLDREAHSSLRMKVYAKE 385
Q LDRE + V A++
Sbjct: 3916 Q--LDRETRDQYTLTVMAQD 3933
Score = 60.5 bits (140), Expect = 3e-07
Identities = 47/154 (30%), Positives = 74/154 (48%), Gaps = 10/154 (6%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E A VL + ++ + +V + +LD+ND P
Sbjct: 4101 SMFSINGTNLRVGSTPLDRE---TAEEHVLDISLTE--GGIVKGLFKVTVNVLDINDETP 4155
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F+ +N+S+ E G L V ATD D G N TY + + +G FSI+ ++ ++
Sbjct: 4156 SFQSPSFNVSVNEIERLGTVFLTVSATDSDAGANSALTYSIAAGNEEGVFSINNKTAAIS 4215
Query: 363 VRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFA 395
V Q LDRE + V A++ PS+ T A
Sbjct: 4216 VAKQ--LDRETRDLYMLTVMAQDGGEPSLNRTAA 4247
Score = 59.7 bits (138), Expect = 6e-07
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E Q +L + ++ +K +V + +LD+ND P
Sbjct: 615 SMFSINGTNLRVGSTPLDRETAAQ---HILDISLTE-GGTIK-GFVKVTVNVLDINDETP 669
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F+ +N+S+ E G L V ATD D G N TY + + +G FSI+ ++G ++
Sbjct: 670 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAIS 729
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
V Q LDRE + V A++
Sbjct: 730 VAKQ--LDRETRDQYTLTVMAQD 750
Score = 59.7 bits (138), Expect = 6e-07
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E Q +L + ++ +K +V + +LD+ND P
Sbjct: 2937 SMFSINGTNLRVGSTPLDRETAAQ---HILDISLTE-GGTIK-GFVKVTVNVLDINDETP 2991
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F+ +N+S+ E G L V ATD D G N TY + + +G FSI+ ++G ++
Sbjct: 2992 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAIS 3051
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
V Q LDRE + V A++
Sbjct: 3052 VAKQ--LDRETRDQYTLTVMAQD 3072
Score = 59.7 bits (138), Expect = 6e-07
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E Q +L + ++ +K +V + +LD+ND P
Sbjct: 3495 SMFSINGTNLRVGSTPLDRETAAQ---HILDISLTE-GGTIK-GFVKVTVNVLDINDETP 3549
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F+ +N+S+ E G L V ATD D G N TY + + +G FSI+ ++G ++
Sbjct: 3550 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGAIS 3609
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
V Q LDRE + V A++
Sbjct: 3610 VAKQ--LDRETRDQYTLTVMAQD 3630
Score = 58.8 bits (136), Expect = 1e-06
Identities = 81/354 (22%), Positives = 146/354 (41%), Gaps = 31/354 (8%)
Query: 993 VINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKT 1048
V++ + G + VA+ L E+ ++ L + A DGG LN +V + V D ND+ PV +
Sbjct: 1741 VMDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 1800
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSVNGE 1107
++ E + V A+D D G N L Y I+ S F+I +G +S+ G
Sbjct: 1801 VIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE-SGAHGHFQIKDSSSGAISLAGM 1859
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
L + YI+ V D G DV P+ +D
Sbjct: 1860 LSYNQRNNYIVVVNVTDGG----SPALKSRAMVVIDVTP-KPRNLTYD------------ 1902
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP--QRKNQQ 1225
+S E+ + + K + G ++ + F NGN L + S P + Q
Sbjct: 1903 VSVLEGEANVQVMDLKPVVSHFNVSGGNFTFFNSSGSMFSINGNNLRVGSTPLDRETAAQ 1962
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELEIEENVNAPVELVSLNLT-- 1282
++ SL+ + V + ++++D+ P+F S + + + E ++++ T
Sbjct: 1963 HVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDG 2022
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ N + Y I N+ F I+ + G + + + DRE +D Y + V A+
Sbjct: 2023 DAGANSALTYSIAAGNEEGF---FSINNKTGAISVAKQLDRETRDQYTLTVMAQ 2073
Score = 58.0 bits (134), Expect = 2e-06
Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 24/168 (14%)
Query: 929 LDVDQLGPLFLIPE-NIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ PLF P N+ + GT + ++A D D+G N + Y
Sbjct: 1986 LDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTY------------- 2032
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKD 1037
S A + +F IN + G + VA+ L E+ ++ L + A DGG LN +V + V D
Sbjct: 2033 SIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 2092
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
ND+ PV + ++ E + V A+D D G N L Y I+
Sbjct: 2093 ANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE 2140
Score = 58.0 bits (134), Expect = 2e-06
Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 20/320 (6%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP---IGPSLTIPLT 133
+ VTV + D+ND P F ++V+V+E+ G F+ + A G + + +
Sbjct: 4137 VKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGT-VFLTVSATDSDAGANSALTYS 4195
Query: 134 VPRG-----LTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
+ G +I A K + D++ V D G +L ++ + +V
Sbjct: 4196 IAAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMAQDGGEPSL---NRTAAVPIQV 4252
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
D + Q ++ I P + A D+D+G L Y + SG
Sbjct: 4253 GDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQIK 4312
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
DS +G++ + L +N V + L + A +++ N N P F
Sbjct: 4313 DSSSGAISVAGRLSYKQRNNYSVVVKVTDGGSLALES---RAIVLIDVTPTTENRNAPVF 4369
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
Y + ++ F VL V+ATD D G NG Y++ + F I+P SG T+R
Sbjct: 4370 ASVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRISEDTDLFYIEPTSG--TIRTA 4427
Query: 367 TVL-DREAHSSLRMKVYAKE 385
+ D++ S V A +
Sbjct: 4428 DIFADKDRGLSFSFMVQASD 4447
Score = 55.6 bits (128), Expect = 1e-05
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 13/217 (5%)
Query: 150 DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIH 209
DK N + YSI SG GHF ++ S + L +L Y+ + +V + G
Sbjct: 1650 DKDIGANGRLMYSIESGAH-GHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGG--- 1705
Query: 210 KEILFPEPIHAIDQDLGVGATLRYEL-ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQ 268
L + ID L Y++ + + + +D G++ + K+LD +
Sbjct: 1706 SPALKSRAMVVIDVT-PKPRNLTYDVSVLEGEANVQVMDLKTGAISVAKQLDRETR---- 1760
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ + L V A P + V I++ D NDN P + +S+ E V V
Sbjct: 1761 -DQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATV 1819
Query: 329 MATDKDQGENGEFTYQLDD-PKGAFSI-DPRSGWLTV 363
+A+DKD G NG Y ++ G F I D SG +++
Sbjct: 1820 IASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISL 1856
Score = 54.4 bits (125), Expect = 2e-05
Identities = 66/230 (28%), Positives = 99/230 (43%), Gaps = 20/230 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD ND P F S + S+ ++GTV V A D D G N + Y + +
Sbjct: 4143 VTVNVLDINDETPSF-QSPSFNVSVNEIERLGTVFLTVSATDSDAGANSALTYSIAAGNE 4201
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F IN T +SVA+ E R + L V A D PS R A V I+V G
Sbjct: 4202 EGV---FSINNKTAAISVAKQLDRETRDLYMLTVMAQD-GGEPSLNR--TAAVPIQV--G 4253
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV--PF 620
+ P P A + I T V + +D + + L++ E G F
Sbjct: 4254 DANDNP--PVIQDAVIRVSLSETAAIDTPVATVIASD--KDIGANGRLMYSIESGAHGHF 4309
Query: 621 AVEE-RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
+++ SG I+V LS R Y V + + +L++ + A V ++DV
Sbjct: 4310 QIKDSSSGAISVAGRLSYKQRNNYSV-VVKVTDGGSLALESRAIV-LIDV 4357
Score = 54.0 bits (124), Expect = 3e-05
Identities = 81/325 (24%), Positives = 138/325 (42%), Gaps = 32/325 (9%)
Query: 470 KSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP-NTGTVSVAESPIL 528
+ A++ T + V A D D+G NG ++Y ++ + F+I ++G +S+A
Sbjct: 483 RETAEIDTPVATVIASDKDIGANGRLMYSIESGA----LGHFQIKDWSSGAISLAGMLSY 538
Query: 529 EGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
R+ V + S S A+V I+VT + D+ G +NV +
Sbjct: 539 NQRNNYIVVVNVTDGG-SPALKSRAIVVIDVTPKPRNLTHDVSVLEGE-------ANVQV 590
Query: 589 GTSVGQIRVNDAFEQNDVSYDLLHGYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEA 647
+ + A +VS ++ G F++ + + L R + +
Sbjct: 591 ------MDLKPAESHFNVSGGNFTFFDSSGSMFSING-TNLRVGSTPLDRETAAQHILD- 642
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
++L E + TV+V+D+NDE + SP F+V N +G +F T +S+
Sbjct: 643 ISLTEGGTIKGFVKVTVNVLDINDETPLF----QSPS-FNVSVNEI-ERLGTVFLT-VSA 695
Query: 708 IYGNGTGN--VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
G+ N + + IA + + G I K LDRE RD Y +TV+A+ + G
Sbjct: 696 TDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQ-DGGEP 754
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHA 790
V I + D NDNPPV + A
Sbjct: 755 PLNSTTAVAIQVGDANDNPPVIQDA 779
Score = 53.6 bits (123), Expect = 4e-05
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 991 YFVINERHGHVIVARSLPPES------EFRLNISALDGGNLNDNISVRVFVKDVNDHFPV 1044
+F IN G +IV ++L E+ R + A D + +++ + + D+ND+ P
Sbjct: 2463 WFRINSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSS-QGSLTAILTITDINDNAPA 2521
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
F+ T + E + + + ATDAD NA +T+ I + F I +TG +++
Sbjct: 2522 FQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDITI 2581
Query: 1105 NGELDRETEDK-YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ LD + + Y L + A +N DV+D F
Sbjct: 2582 SKPLDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANF 2629
Score = 52.8 bits (121), Expect = 7e-05
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 12/192 (6%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+T+ D NDN P F + L S N +G + + A D D N ++ + + +
Sbjct: 2510 LTITDINDNAPAFQNTPL-TVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNE-- 2566
Query: 507 ITSPFKINPNTGTVSVAESPILE-GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
F I+ TG +++++ + G + S + S VVTI +T
Sbjct: 2567 -GEAFSIDKVTGDITISKPLDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINIT----- 2620
Query: 566 NKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGVPFAVE 623
+ D+P +F YE + N +G+ + Q+ D N V Y + + G FA+
Sbjct: 2621 DVDDLPANFSQKLYEAHIDKNSPLGSLITQVHAKDMDSLNAPVEYSIYPDSDPGGLFAIN 2680
Query: 624 ERSGVITVVDDL 635
+ SG +TV +L
Sbjct: 2681 KTSGEVTVDGNL 2692
Score = 51.6 bits (118), Expect = 2e-04
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ FV V V +LD ND P+F S + S+ ++GTV V A D D G N + Y
Sbjct: 651 IKGFVKVTVNVLDINDETPLF-QSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 709
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAV 554
+ + F IN TG +SVA+ E R + L V A D P ++A+
Sbjct: 710 IAAGNE---EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAI 764
Score = 51.6 bits (118), Expect = 2e-04
Identities = 137/624 (21%), Positives = 238/624 (38%), Gaps = 84/624 (13%)
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSY---DLLHGYEEGVPFAV 622
P P G+P FW + T+ G I R+ ++Y D+ H + F +
Sbjct: 2414 PGAPPTFGSP--FWSDVLPEVNTTAGTIITRLTATGGNGTITYSLEDIAHPW-----FRI 2466
Query: 623 EERSGVITVVDDLSRY----NRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
+G + V L R FE A ++ S+ A + + D+ND
Sbjct: 2467 NSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLT--AILTITDINDNAPAF-- 2522
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAIAEDG 736
++P+ EN IG T +++ + T N + F+I + + G
Sbjct: 2523 -QNTPLTVSCSENRP---IGLTVAT-LTATDADATTNAIITFVIVSGNEGEAFSIDKVTG 2577
Query: 737 TIFTQKPLDREKRD-VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
I KPLD +K VY + + A N + VTI I D +D P F YE
Sbjct: 2578 DITISKPLDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAH 2637
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDSL 853
I +NS +G+ I + A D D NA Y+++ + +F +++ +G V G+
Sbjct: 2638 IDKNSPLGSLITQ---VHAKDMD-SLNAPVEYSIYPDSDPGGLFAINKTSGEVTVDGNLR 2693
Query: 854 DREKKIMYK---------LSLVARDTGGLSS-EAELIIMIGDENDNKPEFNQIEENSKVR 903
+ ++ +LV LS+ ++ I+ G+ N + E + V
Sbjct: 2694 NGVYSLIVNAKSTTQPLAFTLVKVTVSTLSNLTYDVSILEGEANVPVMDLKPAESHFNVS 2753
Query: 904 IHRET---------KLNGT---AGFTIIEVKPKNKFALDVD--QLGPLFLIPENIPIGTT 949
T +NGT G T ++ + + LD+ + G + + I T
Sbjct: 2754 GGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKTAEIDTP 2813
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEV--YIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
+ + A D D G NG++ Y S + S+ A+ + N+R+ +++V
Sbjct: 2814 VATVIASDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVV---- 2869
Query: 1008 PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
++ DGG + + R V V D P + Y+ +V E + +V+
Sbjct: 2870 ---------VNVTDGG--SPALKSRAMV--VIDVKPKPRNLTYDVSVLEGEANVQVMDLK 2916
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
A N T+F + F I+ T + + LDRET ++IL + + G
Sbjct: 2917 PAESHFNVSGGNFTFF---DSSGSMFSING-TNLRVGSTPLDRETAAQHILDISLTEGG- 2971
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKF 1151
D+ND +P F
Sbjct: 2972 --TIKGFVKVTVNVLDINDETPLF 2993
Score = 51.6 bits (118), Expect = 2e-04
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 6/130 (4%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F ++S G L + K LD +A N + +V AS ++ + + D+NDN
Sbjct: 2464 FRINSSTGDLIVNKTLDREAMGN-GLGSLRFEVYASDSSSQ---GSLTAILTITDINDNA 2519
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P F+ +S EN P G +V + ATD D N T+ + + AFSID +G +
Sbjct: 2520 PAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDI 2579
Query: 362 TVRNQTVLDR 371
T+ D+
Sbjct: 2580 TISKPLDYDK 2589
Score = 49.2 bits (112), Expect = 9e-04
Identities = 45/141 (31%), Positives = 63/141 (44%), Gaps = 30/141 (21%)
Query: 1079 NLTYFIQPSDTDLPFEISPL-TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
NLTY + + + ++ L TG +SV +LDRET D+Y LTV+A+D G
Sbjct: 1725 NLTYDVSVLEGEANVQVMDLKTGAISVAKQLDRETRDQYTLTVMAQDGG-EPPLNSTTAV 1783
Query: 1138 XXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA 1197
D NDN P V+ V + ++ E A I T VA
Sbjct: 1784 AIQVGDANDNPP--------------------------VIQDAVIRVSLSETAAIDTPVA 1817
Query: 1198 KVFANDTDFIGNGNGLILYSL 1218
V A+D D IG NG ++YS+
Sbjct: 1818 TVIASDKD-IG-ANGRLMYSI 1836
Score = 48.8 bits (111), Expect = 0.001
Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ D+ND+ P F+ T + E + + + ATDAD NA +T+ I + F
Sbjct: 262 ITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFS 321
Query: 1095 ISPLTGVLSVNGELDRETEDK-YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I +TG ++++ LD E + Y L + A +N DV+D F
Sbjct: 322 IDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANF 379
Score = 46.8 bits (106), Expect = 0.005
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 9/137 (6%)
Query: 764 VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA 823
+++ G + I D NDN P F++ EN IG + + ATDAD TNA
Sbjct: 249 LVTRKGKLTAILTITDINDNAPAFQNTPLTVSCSENRPIGLTVA---TLTATDADATTNA 305
Query: 824 LFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREK-KIMYKLSLVARDTGG---LSSEAE 878
+ + + G E F +D+ TG + I LD E +Y L++ A + L S
Sbjct: 306 IITFVIVSGNEGEAFSIDKVTGDIT-ISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGV 364
Query: 879 LIIMIGDENDNKPEFNQ 895
+ I I D +D F+Q
Sbjct: 365 VTINITDVDDLPANFSQ 381
Score = 45.6 bits (103), Expect = 0.011
Identities = 39/137 (28%), Positives = 69/137 (50%), Gaps = 13/137 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + + DANDN PV + + S+ A + T + V A D D+G NG ++Y ++ ++
Sbjct: 4248 VPIQVGDANDNPPV-IQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAH 4306
Query: 505 LTITSPFKI-NPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
F+I + ++G +SVA + R +++ V+ +D + E R A+V I+VT
Sbjct: 4307 ----GHFQIKDSSSGAISVAGRLSYKQRNNYSVVVKVTDGGSLALESR---AIVLIDVTP 4359
Query: 562 GTKGNKPDIPDFMGAPY 578
T+ + P F Y
Sbjct: 4360 TTENR--NAPVFASVQY 4374
Score = 44.8 bits (101), Expect = 0.018
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S+ S+NG+ LD E Q +L + ++ +K +V + +LD+ND P
Sbjct: 3240 SMFSINGTNLRVGSTPLDRETAAQ---HILDISLTE-GGTIK-GFVKVTVNVLDINDETP 3294
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
F+ +N+S+ E G L V ATD D G N TY +
Sbjct: 3295 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI 3335
Score = 44.4 bits (100), Expect = 0.024
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGA 351
+ + D+NDN P F+ +S EN P G +V + ATD D N T+ + + A
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEA 319
Query: 352 FSIDPRSGWLTV 363
FSID +G +T+
Sbjct: 320 FSIDKVTGDITI 331
Score = 42.3 bits (95), Expect = 0.099
Identities = 23/50 (46%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALA-RDAGRVFGF 1489
ATDSD GIN + Y+I +E F I+P SGT+R A +D G F F
Sbjct: 4393 ATDSDTGINGVVEYRI-SEDTDLFYIEPTSGTIRTADIFADKDRGLSFSF 4441
Score = 41.9 bits (94), Expect = 0.13
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D A + + ++SGN+ + FS+D V G + + K LD E+ + T + +
Sbjct: 296 ATDADATTNAIITFVIVSGNEGEAFSIDKVTGDITISKPLDY--ENGPRVYTLNISAMNN 353
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
+ L++ V I + D++D F Y I +N P
Sbjct: 354 HTDLMLQSFGV-VTINITDVDDLPANFSQKLYEAHIDKNSP 393
Score = 38.7 bits (86), Expect = 1.2
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 10/124 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ V ++VT N N PVF S Y + + + V A D D G NG+V Y +
Sbjct: 4351 AIVLIDVTPTTENRNAPVFA-SVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRIS 4409
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALF---VEASDQPANPSERRYSLAVVTI 557
++L F I P +GT+ A+ + R F V+ASD+ P + + + A +TI
Sbjct: 4410 EDTDL-----FYIEPTSGTIRTADIFADKDRGLSFSFMVQASDKGTPPKKTKEN-AHITI 4463
Query: 558 EVTR 561
+ R
Sbjct: 4464 FLLR 4467
Score = 35.9 bits (79), Expect = 8.6
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 6/106 (5%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGV 628
P F P N IG +V + DA + +++ ++ G EG F++++ +G
Sbjct: 270 PAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSG-NEGEAFSIDKVTGD 328
Query: 629 ITVVDDLSRYNRP-MYDFEAVALQENANLSIVT--NATVHVVDVND 671
IT+ L N P +Y A+ + +L + + T+++ DV+D
Sbjct: 329 ITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDD 374
>UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protein
stan precursor; n=10; Sophophora|Rep: Protocadherin-like
wing polarity protein stan precursor - Drosophila
melanogaster (Fruit fly)
Length = 3574
Score = 140 bits (338), Expect = 4e-31
Identities = 131/458 (28%), Positives = 201/458 (43%), Gaps = 32/458 (6%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL-QRTSNL 505
V ++DANDN P F S E S+ N VG I +V+A D D G N + Y + +R N
Sbjct: 677 VNVIDANDNAPRFYTSQFQE-SVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF 735
Query: 506 TITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
P ++P TG V + E GR A V A D P S+ + +V
Sbjct: 736 ----PLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDV---- 787
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE 623
N D P F YE VG + GT V + D E + + Y++ G G FA+
Sbjct: 788 --NDND-PAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRG-RFAIT 843
Query: 624 ERSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
++G +IT+ L Y + VA ++ S +++ D N+ + +
Sbjct: 844 SQNGRGLITIAQSLD-YKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPY 902
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIF 739
S +F ++ G + + T+ + T ++ N D +I + G I
Sbjct: 903 SASVF--EDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIV 960
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T PLDRE Y +TV A+ + G S + V I + D NDN P F+ Y+ I+E+
Sbjct: 961 TNAPLDRETTSGYLLTVTAK-DGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED 1019
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDSLDREK 857
+ +GT + + A+D D G N Y L E F +D +G ++ LDRE
Sbjct: 1020 ALVGTSVIQ---VAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIR-TNKGLDRES 1075
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
++ L+ +A D G LSS E+ I + D ND+ P F
Sbjct: 1076 VAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTF 1113
Score = 123 bits (296), Expect = 4e-26
Identities = 122/474 (25%), Positives = 208/474 (43%), Gaps = 33/474 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR-TS 503
++V +LD ND++P F + +E S++ A VG+ + ++A D D+G+N + Y ++ T
Sbjct: 450 LQVNVLDCNDHSPTF-EAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTD 508
Query: 504 NLTITSP-----FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
+ F+I+ +G +S S E + L V A+D + SERR + A V
Sbjct: 509 GAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQ 568
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGT---SVGQIRVNDAFEQND--VSYDLL 611
++V + + P F Y V + GT +V IR DA + N+ + Y ++
Sbjct: 569 VKVL----DDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAII 624
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVN 670
G + F+++ SG +++V L + Y A + + S T V+V+D N
Sbjct: 625 GGNTQS-QFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDAN 683
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D + EN +G I + + I+ + D
Sbjct: 684 DNAPRFYTSQFQESVL---EN---VPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPL 737
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G + T KPLDRE++ + V+A+ + GV + V I ++D NDN P F
Sbjct: 738 AVDPRTGWVQTIKPLDREEQGRFAFQVVAK-DGGVPPKSASSSVVITVQDVNDNDPAFNP 796
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV-VKF 848
YE + E+ GT + + ATD DE + + T G + F + G +
Sbjct: 797 KYYEANVGEDQPPGTPV---TTVTATDPDEDSRLHYEITT-GNTRGRFAITSQNGRGLIT 852
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
I SLD +++ + L++ A D+GG S A + I I D N+ P F ++ V
Sbjct: 853 IAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASV 906
Score = 122 bits (293), Expect = 1e-25
Identities = 127/464 (27%), Positives = 205/464 (44%), Gaps = 40/464 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V +T+ D NDN+P F P YE ++ + GT + V A DPD ++ + Y++ T
Sbjct: 779 SVVITVQDVNDNDPAFNPK-YYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEIT-TG 834
Query: 504 NLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
N G +++A+S E R L V A+D S R A V I +T
Sbjct: 835 NTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATD-----SGGRSDTATVHINITD 889
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL----LHGYE 615
P F APY V + +GT+V + D+ ++Y L ++G
Sbjct: 890 ANNF----APIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLG 945
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERG 674
PF++ ++G I L R Y A N +LS T+ + V DVND
Sbjct: 946 SPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAP 1005
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ I +++ G ++ Q+ ++ G +++L++++ D+ D + +
Sbjct: 1006 AFKSPLYQASI--LEDALVGTSVIQVAASDPDV---GLNGRIKYLLSDR-DIEDGSFVID 1059
Query: 735 --DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
GTI T K LDRE V+ +T IA +KG + +V I +ED ND+PP F
Sbjct: 1060 PTSGTIRTNKGLDRESVAVFHLTAIA-VDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKI 1118
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK---F 848
++ ENS +G+ + I A D DEG NA+ Y++ G+ F + G +
Sbjct: 1119 TLYVPENSPVGSVV---GEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLL 1175
Query: 849 IGDSLDREKKIMYKLSLVARDTG-GLSSEAELIIMIGDENDNKP 891
LD E + LV R L ++A + I++ D NDN P
Sbjct: 1176 TMTELDYE-STRKRFELVVRAASPPLRNDAHIEILVTDVNDNAP 1218
Score = 110 bits (265), Expect = 2e-22
Identities = 57/170 (33%), Positives = 96/170 (56%), Gaps = 9/170 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G A +RY +I GN + FS+DS++G + L K LD ++ ++ L ++
Sbjct: 606 IRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYES-----VRSYRLVIR 660
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P ++ ++ + ++D NDN P F + S++EN+P G+++++V A D D+G
Sbjct: 661 AQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGA 720
Query: 338 NGEFTYQLDDPKGAF--SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N E TY + + F ++DPR+GW V+ LDRE +V AK+
Sbjct: 721 NAEITYSISERDDNFPLAVDPRTGW--VQTIKPLDREEQGRFAFQVVAKD 768
Score = 107 bits (258), Expect = 2e-21
Identities = 123/508 (24%), Positives = 215/508 (42%), Gaps = 52/508 (10%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
+ T + L++ T + T + E+ + +V+V +LD NDN P F Y
Sbjct: 530 ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQF-SERTYTV 588
Query: 468 SMKSNAKVGT---VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE 524
+ + GT + ++A D D G N + Y + + S F I+ +G VS+ +
Sbjct: 589 QVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNT---QSQFSIDSMSGDVSLVK 645
Query: 525 SPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
E + L + A D + L V I+ + P F + ++ V
Sbjct: 646 PLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDA-------NDNAPRFYTSQFQESV 698
Query: 583 GSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNR 640
NV +G ++ +++ D+ E +++Y + ++ P AV+ R+G + + L R +
Sbjct: 699 LENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDNFPLAVDPRTGWVQTIKPLDREEQ 757
Query: 641 PMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
+ F+ VA S ++ + V DVND + + ++ G +
Sbjct: 758 GRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANV--GEDQPPGTPVTT 815
Query: 700 IFHTNMSS----IYGNGTGNV--RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYR 753
+ T+ Y TGN RF I +Q G I + LD ++ +
Sbjct: 816 VTATDPDEDSRLHYEITTGNTRGRFAITSQNG---------RGLITIAQSLDYKQEKRFL 866
Query: 754 MTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
+TV A + G A ++ I I D N+ P+FE+A Y + E++ +GT + ++
Sbjct: 867 LTVAATDSGGRSDTATVH---INITDANNFAPIFENAPYSASVFEDAPVGTTVL---VVS 920
Query: 814 ATDADEGTNALFMYTLFGE------GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
ATD+D G NA Y+L E + F ++ TG + LDRE Y L++ A
Sbjct: 921 ATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI-VTNAPLDRETTSGYLLTVTA 979
Query: 868 RDTG--GLSSEAELIIMIGDENDNKPEF 893
+D G LS ++ I + D NDN P F
Sbjct: 980 KDGGNPSLSDTTDVEIGVTDVNDNAPAF 1007
Score = 105 bits (253), Expect = 7e-21
Identities = 76/238 (31%), Positives = 109/238 (45%), Gaps = 14/238 (5%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I + N FA + + E+ P+GTT++ ++A D D G+N QI Y N E
Sbjct: 885 INITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEE----- 939
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVF 1034
S + L F IN + G ++ L E S + L ++A DGGN L+D V +
Sbjct: 940 ---SINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIG 996
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-TDLPF 1093
V DVND+ P FK Y ++ E + +V A+D D G N + Y + D D F
Sbjct: 997 VTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF 1056
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I P +G + N LDRE+ + LT +A D G DVND+ P F
Sbjct: 1057 VIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKG-SPPLSSTVEVQIRLEDVNDSPPTF 1113
Score = 103 bits (248), Expect = 3e-20
Identities = 123/485 (25%), Positives = 200/485 (41%), Gaps = 62/485 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +G+T+I L A D D G N +I E+ E + L+ D + F I+ R G
Sbjct: 473 IREGATVGSTVITLRATDQDIGKNAEI--EYGIEAVTDGAGLAQD--QEMPIFRIDSRSG 528
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDN-----ISVRVFVKDVNDHFPVFKKTWYNF 1052
+ SL E+ + L ++A D + SV+V V D ND++P F + Y
Sbjct: 529 VISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTV 588
Query: 1053 NVEEAQY---TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
V E Q+ + + ATDAD G NA + Y I +T F I ++G +S+ LD
Sbjct: 589 QVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLD 648
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADE 1167
E+ Y L + A+D G D NDN+P+FY F E + P
Sbjct: 649 YESVRSYRLVIRAQDGG-SPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVG-- 705
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
+++ + Y + NA I ++++ N + G + P + +Q
Sbjct: 706 ------YNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGR 759
Query: 1228 ----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
G+P S+++ +++TV DV D + P F +YYE + E+ +
Sbjct: 760 FAFQVVAKDGGVPPKSASSSVVITVQDVND-----NDPAFNPKYYEANVGEDQPPGTPVT 814
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
++ T+ E+ ++ Y I N R F I +NG +I A+
Sbjct: 815 TVTATDPDEDSRLHYEITTGN---TRGRFAITSQNGR---------------GLITIAQS 856
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPF 1397
Y +E ++ A D G V + I D N+ +P F N P ++ AP
Sbjct: 857 LDYKQEKRFLLTVAATD--SGGRSDTATVHINITDANNFAPIFENA--PYSASVFEDAPV 912
Query: 1398 GYQVM 1402
G V+
Sbjct: 913 GTTVL 917
Score = 99.5 bits (237), Expect = 6e-19
Identities = 82/240 (34%), Positives = 118/240 (49%), Gaps = 40/240 (16%)
Query: 992 FVINERHGH--VIVARSLP--PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F I ++G + +A+SL E F L ++A D G +D +V + + D N+ P+F+
Sbjct: 840 FAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFEN 899
Query: 1048 TWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDL----PFEISPLTGV 1101
Y+ +V E+A VL V ATD+D G NA +TY + + S L PF I+P TG
Sbjct: 900 APYSASVFEDAPVGTTVL-VVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGA 958
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ N LDRET Y+LTV A+D G DVNDN+P F +
Sbjct: 959 IVTNAPLDRETTSGYLLTVTAKDGG-NPSLSDTTDVEIGVTDVNDNAPAFKS-------- 1009
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR 1221
P+Y+A+I E+A +GT+V +V A+D D +G NG I Y L R
Sbjct: 1010 ------------------PLYQASILEDALVGTSVIQVAASDPD-VGL-NGRIKYLLSDR 1049
Score = 88.2 bits (209), Expect = 2e-15
Identities = 78/250 (31%), Positives = 116/250 (46%), Gaps = 20/250 (8%)
Query: 218 IHAIDQDLGVGATLRYEL----ISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D+GV A + Y L I+G FS++ G++ LD + + +
Sbjct: 919 VSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRET-----TSGY 973
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+L V A NP + VEI + D+NDN P F+ Y SI+E+ G SV+QV A+D
Sbjct: 974 LLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASD 1033
Query: 333 KDQGENGEFTYQLDD---PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NP 388
D G NG Y L D G+F IDP SG T+R LDRE+ + + A + +P
Sbjct: 1034 PDVGLNGRIKYLLSDRDIEDGSFVIDPTSG--TIRTNKGLDRESVAVFHLTAIAVDKGSP 1091
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDK--VGTKTENIEYYDEQLMSFVNVE 446
+ T R+ P T A + T YV P+ VG+ I +D V
Sbjct: 1092 PLSSTVEVQIRLEDVNDSP-PTFASDKITLYV-PENSPVGSVVGEIHAHDPDEGVNAVVH 1149
Query: 447 VTLLDANDNN 456
+++ +D+N
Sbjct: 1150 YSIIGGDDSN 1159
Score = 81.8 bits (193), Expect = 1e-13
Identities = 95/373 (25%), Positives = 152/373 (40%), Gaps = 49/373 (13%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---- 1085
+++V V D NDH P F+ + ++ E + + ATD D G+NA + Y I+
Sbjct: 449 TLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTD 508
Query: 1086 ----PSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARD--NGXXXXXXXXXXXX 1138
D ++P F I +GV+S LDRET D Y L V A D +
Sbjct: 509 GAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQ 568
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI------ 1192
D NDN P+F + + PE D+ +V I A NA I
Sbjct: 569 VKVLDDNDNYPQF--SERTYTVQVPE-DQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG 625
Query: 1193 GTTVAKV----FANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE 1248
G T ++ + D + + + S Q+ G PS S+T L+V V D D
Sbjct: 626 GNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDAND- 684
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNENDTDIRRTFV 1307
+ P F + ++ + ENV ++ + + E Y ++E D +
Sbjct: 685 ----NAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNF--PLA 738
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV 1367
+DPR G + ++ DRE E+ +++ ++ VA+D VV
Sbjct: 739 VDPRTGWVQTIKPLDRE-----------EQGRFAFQV------VAKDGGVPPKSASSSVV 781
Query: 1368 VRIKDVNDNSPKF 1380
+ ++DVNDN P F
Sbjct: 782 ITVQDVNDNDPAF 794
Score = 81.4 bits (192), Expect = 2e-13
Identities = 95/355 (26%), Positives = 144/355 (40%), Gaps = 31/355 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
V + + DAN+ P+F + Y S+ +A VGT + V A D D+G N + Y L S
Sbjct: 883 VHINITDANNFAPIFENAP-YSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESI 941
Query: 504 -NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
L PF INP TG + V +P+ + L V A D NPS T +V
Sbjct: 942 NGLGSPDPFSINPQTGAI-VTNAPLDRETTSGYLLTVTAKD-GGNPS------LSDTTDV 993
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEG 617
G + P F Y+ + + +GTSV Q+ + D + Y L E
Sbjct: 994 EIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIED 1053
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F ++ SG I L R + ++ A+A+ + + LS + + DVND
Sbjct: 1054 GSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTF 1113
Query: 677 LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
A I +V ENS G+ +G+I H + N V + I D +
Sbjct: 1114 ---ASDKITLYVPENSPVGSVVGEI-HAHDPDEGVNAV--VHYSIIGGDDSNAFSLVTRP 1167
Query: 736 GT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G+ + T LD E V+ + + + A + I + D NDN PV
Sbjct: 1168 GSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDA---HIEILVTDVNDNAPV 1219
Score = 78.2 bits (184), Expect = 2e-12
Identities = 70/238 (29%), Positives = 105/238 (44%), Gaps = 15/238 (6%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L YE+ +GN R F++ S NG + LD + Q F+L V A+ TA
Sbjct: 827 LHYEITTGNTRGRFAITSQNGRGLITIAQSLDYK---QEKRFLLTVAATDSGGRSDTAT- 882
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK- 349
V I + D N+ P FE Y+ S+ E+ P G +VL V ATD D G N + TY L++
Sbjct: 883 -VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESI 941
Query: 350 ------GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIAK 402
FSI+P++G + LDRE S + V AK+ NPS+ T +
Sbjct: 942 NGLGSPDPFSINPQTG--AIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999
Query: 403 WRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV 460
+PL + + + VGT + D + ++ L D + + FV
Sbjct: 1000 VNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFV 1057
Score = 70.9 bits (166), Expect = 2e-10
Identities = 63/213 (29%), Positives = 98/213 (46%), Gaps = 28/213 (13%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + T LDRE DV+ V+A + +G + + + D ND+ P FE +E
Sbjct: 414 GVVTTSASLDRELMDVHYFRVVAT-DDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEAS 472
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--------FGEGKEM--FDVDENTGV 845
I E + +G+ + ++ATD D G NA Y + + +EM F +D +GV
Sbjct: 473 IREGATVGSTV---ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV 529
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSE-----AELIIMIGDENDNKPEFNQIEENS 900
+ SLDRE Y L + A D SE A + + + D+NDN P+F+ E
Sbjct: 530 IS-TRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTY 586
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQ 933
V++ E + GT T+ ++ A D DQ
Sbjct: 587 TVQV-PEDQWGGTEDNTVAHIR-----ATDADQ 613
Score = 68.5 bits (160), Expect = 1e-09
Identities = 85/361 (23%), Positives = 142/361 (39%), Gaps = 38/361 (10%)
Query: 43 LVDSDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
+VDSD +V +F++ D R+ L S Y +Y+ V + P
Sbjct: 323 IVDSDHRLKIVYHHQ--EFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAV-- 378
Query: 103 HVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYS 162
TV P +++ + V + + DR+ DVHY
Sbjct: 379 -TTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDREL-----MDVHYF 432
Query: 163 IVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL----VIMASGKRIHKEILFPEPI 218
V DD F S L VLD + F+ + G + ++ +
Sbjct: 433 RVVATDDS-FPPRSG--TTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVI---TL 486
Query: 219 HAIDQDLGVGATLRYE---------LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA 269
A DQD+G A + Y L + +F +DS +G + LD + +
Sbjct: 487 RATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSY-- 544
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF---SVL 326
+ V + + +TA A V++++LD NDN P+F Y + + E+ G +V
Sbjct: 545 HLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVA 604
Query: 327 QVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+ ATD DQG N Y + + + FSID SG +++ LD E+ S R+ + A+
Sbjct: 605 HIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKP--LDYESVRSYRLVIRAQ 662
Query: 385 E 385
+
Sbjct: 663 D 663
Score = 68.5 bits (160), Expect = 1e-09
Identities = 77/276 (27%), Positives = 122/276 (44%), Gaps = 25/276 (9%)
Query: 410 TNAPLEK-TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFS 468
TNAPL++ TT + V K + L +VE+ + D NDN P F S LY+ S
Sbjct: 961 TNAPLDRETTSGYLLTVTAKDGG----NPSLSDTTDVEIGVTDVNDNAPAF-KSPLYQAS 1015
Query: 469 MKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPIL 528
+ +A VGT + +V A DPD+G NG + Y L + F I+P +GT+ +
Sbjct: 1016 ILEDALVGTSVIQVAASDPDVGLNGRIKYLL--SDRDIEDGSFVIDPTSGTIRTNKGLDR 1073
Query: 529 EGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNV 586
E L A D+ + P + V +++ + P P F +V N
Sbjct: 1074 ESVAVFHLTAIAVDKGSPPLS-----STVEVQIRLEDVNDSP--PTFASDKITLYVPENS 1126
Query: 587 GIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAV-----EERSGVITVVDDLSRYNR 640
+G+ VG+I +D E N V + + G ++ F++ ER+ ++T+ + Y
Sbjct: 1127 PVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTE--LDYES 1184
Query: 641 PMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
FE V + L + + V DVND VL
Sbjct: 1185 TRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVL 1220
Score = 65.3 bits (152), Expect = 1e-08
Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 5/169 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y + +D ++D G + K LD + + F QV
Sbjct: 711 VQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQ-----GRFAFQVV 765
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K+A + V I + D+NDN P F +Y ++ E+ P G V V ATD D+
Sbjct: 766 AKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDS 825
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ + +G F+I ++G + LD + + V A ++
Sbjct: 826 RLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDS 874
Score = 62.5 bits (145), Expect = 9e-08
Identities = 65/218 (29%), Positives = 92/218 (42%), Gaps = 23/218 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ +GT++I++ A D D GLNG+I+Y L +D FVI+ G
Sbjct: 1016 ILEDALVGTSVIQVAASDPDVGLNGRIKY------------LLSDRDIEDGSFVIDPTSG 1063
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + L ES F L A+D G+ L+ + V++ ++DVND P F V
Sbjct: 1064 TIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVP 1123
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG----VLSVNGELDRE 1111
E V+G++ A D D G NA + Y I D F + G L ELD E
Sbjct: 1124 ENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYE 1183
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ K VV DVNDN+P
Sbjct: 1184 STRKRFELVV---RAASPPLRNDAHIEILVTDVNDNAP 1218
Score = 54.8 bits (126), Expect = 2e-05
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 9/152 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
IHA D D GV A + Y +I G+D FSL + GS + + ++ F L V+
Sbjct: 1135 IHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVR 1194
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLP---EFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A+ + PL+ A +EI + D+NDN P +F+V F N ++ P+G + ++ A D D
Sbjct: 1195 AA--SPPLRN-DAHIEILVTDVNDNAPVLRDFQVIFNNFR--DHFPSG-EIGRIPAFDAD 1248
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
+ + + ++ SG L + Q
Sbjct: 1249 VSDKLHYRILSGNNANLLRLNSSSGGLVLSPQ 1280
Score = 48.4 bits (110), Expect = 0.002
Identities = 91/420 (21%), Positives = 162/420 (38%), Gaps = 56/420 (13%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
+S+ RL I ND R +++ + P F++ Y +V E Q + V A
Sbjct: 325 DSDHRLKI-VYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRA 383
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
D + + S + F++ TGV++ + LDRE D + VVA D+
Sbjct: 384 RDPEDSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDD-SFP 442
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEEN 1189
D ND+SP F A E E E + + +V+ + I +N
Sbjct: 443 PRSGTTTLQVNVLDCNDHSPTFEA--EQFEASIREGATVGS----TVITLRATDQDIGKN 496
Query: 1190 APIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN--QQNLGLPSLSSTAI-LMVTVADVP 1246
A I + V D + + ++ + R L +S + L+VT AD+
Sbjct: 497 AEIEYGIEAV--TDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLA 554
Query: 1247 D------------EVEMSDK----PVFISRYYELEIEENVNAPVE---LVSLNLT--EHY 1285
+V++ D P F R Y +++ E+ E + + T +
Sbjct: 555 SAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQG 614
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N +RY I+ N + F ID +G + LV+ D E +Y +++R
Sbjct: 615 NNAAIRYAIIGGN---TQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIR----------- 660
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
A+D +++V + D NDN+P+F ++ P GY +++++
Sbjct: 661 ------AQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQ--FQESVLENVPVGYNIIRVQ 712
Score = 46.4 bits (105), Expect = 0.006
Identities = 49/167 (29%), Positives = 77/167 (46%), Gaps = 36/167 (21%)
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL---ESSHKPVLL 183
+L +P P G ++ +I A D D+ N+ VHYSI+ G+D F+L S + LL
Sbjct: 1119 TLYVPENSPVG-SVVGEIHAHDPDEG--VNAVVHYSIIGGDDSNAFSLVTRPGSERAQLL 1175
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRI----HKEILFPE-----PI-------------HAI 221
LDY++ K F+LV+ A+ + H EIL + P+ H
Sbjct: 1176 TMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFP 1235
Query: 222 DQDLG--------VGATLRYELISGNDRKLFSLDSVNGSLFLEKELD 260
++G V L Y ++SGN+ L L+S +G L L +L+
Sbjct: 1236 SGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLN 1282
Score = 44.8 bits (101), Expect = 0.018
Identities = 67/253 (26%), Positives = 114/253 (45%), Gaps = 27/253 (10%)
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
+NF + Y A++ E+AP+GTTV V A D+D +G N I YSL ++ LG P
Sbjct: 891 NNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD-VG-VNAQITYSL-NEESINGLGSP 947
Query: 1231 ---SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
S++ +VT A + D S + ++ + VE+ ++ ++
Sbjct: 948 DPFSINPQTGAIVTNAPL-DRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPA 1006
Query: 1288 FKMRYY---ILNEN--DTDIRRTFVIDP---RNGTLYLVRSPDREVKDTYEVI------V 1333
FK Y IL + T + + DP NG + + S DR+++D VI +
Sbjct: 1007 FKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLS-DRDIEDGSFVIDPTSGTI 1065
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYD--VKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
R + RE + + A V +G V+V +R++DVND+ P F + + +
Sbjct: 1066 RTNK-GLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDK--ITLYV 1122
Query: 1392 PTTAPFGYQVMQL 1404
P +P G V ++
Sbjct: 1123 PENSPVGSVVGEI 1135
Score = 43.6 bits (98), Expect = 0.043
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 13/137 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P+G+ + +++A D D G+N + Y I +A +L +
Sbjct: 1122 VPENSPVGSVVGEIHAHDPDEGVNAVVHYSI-----IGGDDSNAFSLVTRP----GSERA 1172
Query: 1000 HVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
++ L ES F L + A ND + + V DVND+ PV + FN
Sbjct: 1173 QLLTMTELDYESTRKRFELVVRAASPPLRND-AHIEILVTDVNDNAPVLRDFQVIFNNFR 1231
Query: 1057 AQYTRRVLGKVDATDAD 1073
+ +G++ A DAD
Sbjct: 1232 DHFPSGEIGRIPAFDAD 1248
Score = 38.3 bits (85), Expect = 1.6
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 1441 ATDSDIGINADIRYQILNEQAP--RFAIDPVSGTVRVVAALARDAGRVF 1487
A+D D+G+N I+Y + + F IDP SGT+R L R++ VF
Sbjct: 1031 ASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVF 1079
Score = 35.9 bits (79), Expect = 8.6
Identities = 23/56 (41%), Positives = 35/56 (62%), Gaps = 3/56 (5%)
Query: 1434 NGLTSPQATDSDIGINADIRYQIL--NEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
N + +ATD+D G NA IRY I+ N Q+ +F+ID +SG V +V L ++ R +
Sbjct: 601 NTVAHIRATDADQGNNAAIRYAIIGGNTQS-QFSIDSMSGDVSLVKPLDYESVRSY 655
>UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to CG7749-PA
- Nasonia vitripennis
Length = 4840
Score = 139 bits (337), Expect = 5e-31
Identities = 211/858 (24%), Positives = 361/858 (42%), Gaps = 82/858 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPR 136
+Y SV V++ D+NDN PIF Y V V E P + A G + + L +
Sbjct: 406 SYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVG 465
Query: 137 G-----LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDY 190
G I D P + Y++ VS D G+ + + V+D
Sbjct: 466 GNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIY-VIDT 524
Query: 191 DAGDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
+ D EF+ LV + + + + A D+D G A + Y I R F +
Sbjct: 525 NDNDPEFEKSEMLVYLDENEPAGTSVC---KVVARDKDSGENAYISYS-IDNIKRVPFEI 580
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT-AQARVEIELLDLNDNLPE 305
D +G + ++ LD + ++L V+A+ P + ++ ++ I+L ++NDN P+
Sbjct: 581 DHFSGVVKTKQLLDYET----MKREYLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQ 636
Query: 306 FE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWL 361
FE +D + + G ++ V A D D G TY++ + G F++DP SG L
Sbjct: 637 FEKIDCVG-HVSRYVQVGTEIITVSAIDFDAGNI--ITYRIVSGGNADGCFALDPTSGVL 693
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
+V + D + + T+ + V T K + P E +
Sbjct: 694 SVACD-LSDLKTQEMIVNVTATDGTHFADVNTLRIHLVNVKRAQGPQSKLLTDETGGFEC 752
Query: 422 PDKVGTK--TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNL---YEFSMKSNAKVG 476
D + TE I ++ M E +++ + V P L E + +A +G
Sbjct: 753 RDTGVARRLTEAIASAEKNNMRSSEDEYSMMPSRYGENVHAPEFLDFPNEIRVNESAPIG 812
Query: 477 TVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFV 536
V+ ++ A D DLG NG ++Y + + S F I+P+TG + + E F+
Sbjct: 813 FVLARLAARDRDLGYNGKLVYGISAGDS---DSVFGIDPDTGELRLIGRLDREREDEYFL 869
Query: 537 EASDQPANPSERRYS--LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ 594
+ ++ S LAV ++V + P F A F V GT + +
Sbjct: 870 NITVYDLGKPQKSASRMLAVSVLDV-------NDNAPKFEKALASFRVSEAALNGTIIFR 922
Query: 595 IRVNDA--FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
DA E V+Y L+ + F V+ +GV+TV L R + Y+ A +
Sbjct: 923 ANTTDADLGENAQVAYSLVTDTSD---FRVDRTTGVLTVFGKLDRERQSSYELRIRATDK 979
Query: 653 NA----------NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIF 701
N N ++ + A V V V+D K A + V+E+ + I I
Sbjct: 980 NGGNDKGEPDFDNPALYSEALVR-VSVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIE 1038
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEF 760
T+ G G G + + + + + I + GTI + + LD E+R V+ +T++A+
Sbjct: 1039 ATDPDE--GPG-GIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAK- 1094
Query: 761 NKG--VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
+KG +S I + + +EN + PVF + EN + T + +KA DAD
Sbjct: 1095 DKGEPSLSSETILIIEVVDVNENLHAPVFNDFVISASVSENQPLNTLVTQ---VKAKDAD 1151
Query: 819 -EGTNALFMYTL-FGEGKEMFDVDENTGV-VKFIGDSLDREKKIMYKLSLVARDTG--GL 873
G ++ Y++ G+G +F +D+ + K + LD E K Y L++ A+D G L
Sbjct: 1152 PPGGDSRIGYSIRGGDGVGLFSIDDEGNIRTKAV---LDVEAKAGYWLTVYAQDHGVVPL 1208
Query: 874 SSEAELIIMIGDENDNKP 891
SS+ ++ + + DENDN P
Sbjct: 1209 SSKLQVYVEVLDENDNTP 1226
Score = 128 bits (310), Expect = 9e-28
Identities = 131/489 (26%), Positives = 212/489 (43%), Gaps = 47/489 (9%)
Query: 431 NIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
NI YD Q + + V++LD NDN P F + L F + A GT+I + D
Sbjct: 870 NITVYDLGKPQKSASRMLAVSVLDVNDNAPKFEKA-LASFRVSEAALNGTIIFRANTTDA 928
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD----- 540
DLG+N V Y L +T TS F+++ TG ++V E + + L + A+D
Sbjct: 929 DLGENAQVAYSL-----VTDTSDFRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGN 983
Query: 541 ---QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV 597
+P + YS A+V + V + P F Y V +V + + + I
Sbjct: 984 DKGEPDFDNPALYSEALVRVSVD----DVNDNAPKFALTSYTVKVREDVPVWSVIAVIEA 1039
Query: 598 NDAFEQND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA- 654
D E + Y E F +++ SG I + L R ++ VA +
Sbjct: 1040 TDPDEGPGGIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEP 1099
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN--- 711
+LS T + VVDVN+ H+P+ F+ SA + Q +T ++ +
Sbjct: 1100 SLSSETILIIEVVDVNEN-------LHAPV-FNDFVISASVSENQPLNTLVTQVKAKDAD 1151
Query: 712 ---GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
G + + I V +I ++G I T+ LD E + Y +TV A+ + GV+ +
Sbjct: 1152 PPGGDSRIGYSIRGGDGV-GLFSIDDEGNIRTKAVLDVEAKAGYWLTVYAQ-DHGVVPLS 1209
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
QV + + DENDN P+ E Y ++ENS G + I+A D D
Sbjct: 1210 SKLQVYVEVLDENDNTPLTEQPVYYPSVLENSPAGVSVLQ---IRAFDRDVSPQQFSFAI 1266
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDE 886
G + F ++ +G++ G LDRE + + L + RD G LSS +++ + D
Sbjct: 1267 TSGNAEGYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDV 1326
Query: 887 NDNKPEFNQ 895
ND+ P F +
Sbjct: 1327 NDHSPVFEE 1335
Score = 127 bits (307), Expect = 2e-27
Identities = 222/936 (23%), Positives = 374/936 (39%), Gaps = 130/936 (13%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+ D SF +++ +L AN ++P F+ + + E S+ N G ++ V A D D G
Sbjct: 2560 NVSVSDGVYTSFARIKIEILPANRHHPKFL-NPVVEVSVLENQLPGKLVTSVLATDKDFG 2618
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
+ G + Y + + F+I+ G + V + + +H LF A+ +
Sbjct: 2619 EYGTIEYSINSDY---LKEFFEIDRENGDI-VTKKSLDREKHKLF--EIPVMASDGGGKS 2672
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSY 608
+V ++VT + P F+ Y+ + N+ + ++ +++ DA E + + Y
Sbjct: 2673 GFVIVRVKVT----DENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIY 2728
Query: 609 DLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+ + F + +G + + + + V Q+ S H
Sbjct: 2729 SIFEPQNSEIKNIFGINPDTGAVFLKKSAKPWETQPFQL-FVRAQDKGLAS-------HH 2780
Query: 667 VDVNDERGVLLKGAHS-PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
VDV E + + G P +F KE+ F + +S G +R +
Sbjct: 2781 VDVPVE--IYIMGPEDIPPLFERKEDK--------FFVSETSTIGTPITRLRTVTNTNST 2830
Query: 726 VTDDIAIAEDGTIFTQKP----------LDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
VT + A D F P LDRE +D Y + V+AE + A + ++T+
Sbjct: 2831 VTCRLVSAGDDFPFAVDPKTCRVTLSGNLDREVKDSYMIGVLAETDSSPPLTA-LAEITL 2889
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ DEND+ P FE Y + EN + GT I + A D D G+N Y+ FG
Sbjct: 2890 QVLDENDHAPKFESNPYSIAVAENIEEGTSILK---VVAHDNDLGSNGEVRYS-FGS--- 2942
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
D+ E V F D+ TG +SS ++ + E + +F
Sbjct: 2943 --DIGELANV--FTIDAY----------------TGWISS----LVQLDKEQQPEYKFQV 2978
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
I ++ H + T+ ++ N A + G + E+ GT +++L
Sbjct: 2979 IATDNGNPRH----FSRTSVLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVELTT 3034
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRL 1015
+D D+ LN + + YI +S D + F I G V VA++L E+ R
Sbjct: 3035 VDKDTELNTALDF------YI----ISGDP---RSQFAIRST-GQVYVAKALDRETRDRY 3080
Query: 1016 NISALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
+ + G V V V DVND+ P K Y + E + + V ATD D
Sbjct: 3081 ELLVVGTDGKFVFETRVIVQVLDVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDD 3140
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
NA L +++ + F + TGVL G+LDRE++ KYILT +D
Sbjct: 3141 EPNAKLRFYLTGGKNE-KFSLDKETGVLKTVGQLDRESQAKYILTAHVQDR-DKTSWECS 3198
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D+NDN+P+F + PE E+ ++ AT +++ I
Sbjct: 3199 SQLEILISDLNDNAPRFSM--QSYSATLPEDVEVGT-------LVTKVHAT-DDDIGINR 3248
Query: 1195 TVAKVF---ANDTDFIGNGNGLILYSLP---QRKNQQNL-------GLPSLSSTAILMVT 1241
+ F AND I +G++ + P + K N+ G P LSS L+V
Sbjct: 3249 KIRYEFLDSANDHFVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVN 3308
Query: 1242 VADVPDEVEMSDKPVFISRYYELEIEE--NVNAPVELVSLNLTEHYENFKMRYYILNEND 1299
V D+ D + P F S+YY + E V V V + N + Y I+ N+
Sbjct: 3309 VQDIND-----NPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADVYYTIVGGNE 3363
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ F ID ++G + + D E Y + ++A
Sbjct: 3364 ---HKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQA 3396
Score = 122 bits (294), Expect = 8e-26
Identities = 127/480 (26%), Positives = 224/480 (46%), Gaps = 51/480 (10%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKS-NAKVGTVIGKVKAVDPDLGQNGMVL 496
Q ++ V VT+LD NDN P+FV NL +++ S +A+ G VI KV A+D D G NG V
Sbjct: 2151 QRVAHTIVNVTVLDINDNCPIFV--NLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVR 2208
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLA 553
Y+L++ FK+N TG +S+ ++ LEG + L + A D +P
Sbjct: 2209 YELKKGHG----ELFKVNRKTGEISLKQN--LEGHNREYQLMIAAYDGGISPC------- 2255
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
++E++ K +P F Y V ++ + + + ++ + Y + G
Sbjct: 2256 --SVEISVNVKVIDRSMPVFDKQFYTDSVLESIEVHSPLALSIQAESPLNRKLIYSITKG 2313
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+ FA++ +GVI VVD+L + Y+ A + + ++ V+DVND
Sbjct: 2314 -NDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAEVLVSILVLDVND-- 2370
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG--NGTG---NVRFLIANQ----- 723
P F + + +F T + + N TG +R+ I N+
Sbjct: 2371 --------CPPEFSQDSYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADEL 2422
Query: 724 -QDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
++ D + E+G ++ ++ LD E D + TV+A ++GV S + V + + D N
Sbjct: 2423 GENTLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVA-MDRGVPSLSSTAHVWLTVIDMN 2481
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DNPP FE ++Y F+ E ++ G + ++ A+D D + L + G ++ + +D+
Sbjct: 2482 DNPPKFEQSSYNCFLSEEAERGQFV---TVVSASDPDLLDDKLVYTIVGGNDQQTYSIDQ 2538
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF-NQIEENS 900
+TG++ I + K M L++ D G +S A + I I N + P+F N + E S
Sbjct: 2539 STGIITLINMQNFADDK-MTLLNVSVSD-GVYTSFARIKIEILPANRHHPKFLNPVVEVS 2596
Score = 116 bits (280), Expect = 4e-24
Identities = 185/752 (24%), Positives = 311/752 (41%), Gaps = 91/752 (12%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAVEERSGVI 629
P F Y+ V + + V +++V+DA + +N + + + G EG F + +G++
Sbjct: 422 PIFSTEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVGGNEGGEFYINADTGML 481
Query: 630 TVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATV--HVVDVNDERGVLLKGAHSPIIF 686
L + Y A+ Q NA ++A V +V+D ND K S ++
Sbjct: 482 YTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDTNDNDPEFEK---SEMLV 538
Query: 687 HVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
++ EN AG ++ ++ + S + + I N + V +I G + T++ LD
Sbjct: 539 YLDENEPAGTSVCKVVARDKDS---GENAYISYSIDNIKRVPFEIDHFS-GVVKTKQLLD 594
Query: 746 RE--KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
E KR+ Y + V A Q+ I + + NDN P FE G + ++G
Sbjct: 595 YETMKRE-YLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQFEKIDCVGHVSRYVQVG 653
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
TEI + A D D G + G F +D +GV+ D D + + M +
Sbjct: 654 TEIIT---VSAIDFDAGNIITYRIVSGGNADGCFALDPTSGVLSVACDLSDLKTQEMI-V 709
Query: 864 SLVARDTGGLSSEAELII-MIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
++ A D + L I ++ + P+ + + + R+T + I +
Sbjct: 710 NVTATDGTHFADVNTLRIHLVNVKRAQGPQSKLLTDETGGFECRDTGVARRLTEAIASAE 769
Query: 923 PKN------KFALDVDQLG-----PLFL-------IPENIPIGTTIIKLNALDLDSGLNG 964
N ++++ + G P FL + E+ PIG + +L A D D G NG
Sbjct: 770 KNNMRSSEDEYSMMPSRYGENVHAPEFLDFPNEIRVNESAPIGFVLARLAARDRDLGYNG 829
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
++ Y ++ + D E++ +I E E+ LNI+ D G
Sbjct: 830 KLVYGISAGDSDSVFGIDPDTGELR-----------LIGRLDREREDEYFLNITVYDLGK 878
Query: 1025 LNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
+ S + V V DVND+ P F+K +F V EA ++ + + TDAD G+NA + Y
Sbjct: 879 PQKSASRMLAVSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGENAQVAY 938
Query: 1083 FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD-NGXXX---------XXX 1132
+ +D F + TGVL+V G+LDRE + Y L + A D NG
Sbjct: 939 SLVTDTSD--FRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDKGEPDFDNPALY 996
Query: 1133 XXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI 1192
DVNDN+PKF L + +++ + +I V +AT + P
Sbjct: 997 SEALVRVSVDDVNDNAPKF----ALTSYTVKVREDVPVWS-----VIAVIEATDPDEGP- 1046
Query: 1193 GTTVAKVFANDTD---FIG----NGNGLILYSLPQRKNQ--------QNLGLPSLSSTAI 1237
G + F+ + + F G +G L L + Q ++ G PSLSS I
Sbjct: 1047 GGIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSETI 1106
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
L++ V DV + + PVF + EN
Sbjct: 1107 LIIEVVDVNENLH---APVFNDFVISASVSEN 1135
Score = 112 bits (270), Expect = 6e-23
Identities = 123/473 (26%), Positives = 205/473 (43%), Gaps = 40/473 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNA-KVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
V ++D ND+ P S +Y + N + G I ++ A DL ++ + Y L +
Sbjct: 1526 VKVIDINDHRPELSES-IYHVEISENVVEKGEAILQLHA--QDLDEDKKLFYSLHNAQSQ 1582
Query: 506 TITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
F ++ TGT+++ E+ E H L V DQ P++R ++ +VT+
Sbjct: 1583 ASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQ-GTPAKRNFARVLVTVH----- 1636
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFA 621
+ P F+ + V IGT+V Q+ D E +SY + G G F+
Sbjct: 1637 -DHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSMTSG-NVGNVFS 1694
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGA 680
++ G I V +L Y V ++ + ++ + VHV V + D +
Sbjct: 1695 IDPDLGTIRVARELDLATASEYIL-LVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRS 1753
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ + + EN IG + I T +++F I + G I T
Sbjct: 1754 GAELAAEIYENEE---IGSF----VKHIEARSTSSLQFEIVSGNIGEAFFINPSTGVIST 1806
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
Q+ LD E Y +++ A G + V +++ D NDN P F A Y G + E +
Sbjct: 1807 QERLDYEDVKFYNLSIAATSMSGASAQCN---VIVHVLDRNDNAPQFVQAVYTGQVSEAA 1863
Query: 801 KIGTEIKMDN------IIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGDSL 853
IG+ + N +IKA DAD NAL Y + E ++ F +D +TG ++ + L
Sbjct: 1864 SIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVEELPRKFFHIDSSTGAIRTV-MLL 1922
Query: 854 DREKKIMYKLSLVARDTG--GLSSE--AELIIMIGDENDNKPEFNQIEENSKV 902
D E ++ ++ D G LSSE A++II + D ND P+F Q + N+ V
Sbjct: 1923 DHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATV 1975
Score = 111 bits (268), Expect = 1e-22
Identities = 136/497 (27%), Positives = 206/497 (41%), Gaps = 35/497 (7%)
Query: 416 KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV 475
K YV K + + + L + V VT+LD ND NP+F P+ YE ++ + V
Sbjct: 165 KDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLNPLFYPTE-YEATVTEDTPV 223
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HA 533
I KV A D DLG NG + Y T F ++P +G V++ R +
Sbjct: 224 HKSILKVSAEDADLGTNGEIYYSFAEK-----TEQFAVHPVSGVVTLTRPLRYVERPLYE 278
Query: 534 LFVEASDQPA-NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
L V+A D+ A R S A +TI V R + P+I P E SN V
Sbjct: 279 LTVQARDRGALYRMTPRASNARLTIHV-RQVNLHAPEI-SVRHLP-EILEHSNADTYAIV 335
Query: 593 GQIRVNDAFEQNDVSYDLLHGYEEG------VPFAVEERSGVITVVDDLSRYNRPMYDFE 646
+ + S +++ G +G +P E V+ ++D +
Sbjct: 336 RVLDRDTGPHGEIASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLTLR 395
Query: 647 AVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
AV S + VH+ D+ND + S I+ VK + +S
Sbjct: 396 AVDRGTPPRFSY-KSVPVHLADLNDNAPIF-----STEIYDVKVPETAPVNSPVIRLKVS 449
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA--EFNKGV 764
V I + + A+ G ++T PLD E + Y +TV A + N G
Sbjct: 450 DADQGKNALVFLEIVGGNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGT 509
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+ +V IY+ D NDN P FE + ++ EN GT + + A D D G NA
Sbjct: 510 RKQSSA-KVKIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCK---VVARDKDSGENAY 565
Query: 825 FMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE-KKIMYKLSLVARDTG---GLSSEAELI 880
Y++ + F++D +GVVK LD E K Y L + A D G SE +L
Sbjct: 566 ISYSIDNIKRVPFEIDHFSGVVK-TKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQLR 624
Query: 881 IMIGDENDNKPEFNQIE 897
I + + NDN+P+F +I+
Sbjct: 625 IKLRNVNDNRPQFEKID 641
Score = 106 bits (254), Expect = 5e-21
Identities = 163/612 (26%), Positives = 258/612 (42%), Gaps = 82/612 (13%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE+ D Y + + ++ G + + + + D NDN P FE A + E + G
Sbjct: 859 LDREREDEYFLNITV-YDLGKPQKSASRMLAVSVLDVNDNAPKFEKALASFRVSEAALNG 917
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T I N TDAD G NA Y+L + + F VD TGV+ G LDRE++ Y+L
Sbjct: 918 TIIFRAN---TTDADLGENAQVAYSLVTDTSD-FRVDRTTGVLTVFG-KLDRERQSSYEL 972
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
+ A D G + + E + DN +++ + VR+ + + F +
Sbjct: 973 RIRATDKNGGNDKGE------PDFDNPALYSE----ALVRVSVDDVNDNAPKFALTSYTV 1022
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
K + E++P+ + I + A D D G G I Y F+ E
Sbjct: 1023 K---------------VREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEE---------- 1057
Query: 984 DALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVN 1039
+E + +F I++ G + + L E L I A D G +L+ + + V DVN
Sbjct: 1058 --MESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSETILIIEVVDVN 1115
Query: 1040 D--HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEIS 1096
+ H PVF + +V E Q ++ +V A DAD G ++ + Y I+ D F I
Sbjct: 1116 ENLHAPVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGDGVGLFSID 1175
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
G + LD E + Y LTV A+D+G D NDN+P E
Sbjct: 1176 D-EGNIRTKAVLDVEAKAGYWLTVYAQDHG-VVPLSSKLQVYVEVLDENDNTP----LTE 1229
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
+ +P E S SV+ I + + + A I + +GLI
Sbjct: 1230 QPVY-YPSVLENSPAGV-SVLQIRAFDRDVSPQ-QFSFAITSGNAEGYFLINSTSGLITT 1286
Query: 1217 S--LPQRKNQ---------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
S R+NQ ++ G P LSST ++V V DV D PVF ++Y ++
Sbjct: 1287 SGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDH-----SPVFEEKFYMVQ 1341
Query: 1266 I--EENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
I +++ P+ V + + +N K++Y I + + F I P G +Y R
Sbjct: 1342 IPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKSGKG---KGKFKIHPDTGMVYSQRG--F 1396
Query: 1324 EVKDTYEVIVRA 1335
E +E+I+RA
Sbjct: 1397 EAGQEFEMIIRA 1408
Score = 103 bits (246), Expect = 5e-20
Identities = 114/487 (23%), Positives = 200/487 (41%), Gaps = 35/487 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + + V V +LD NDN P + Y + + G+ + V A D D N +
Sbjct: 3088 DGKFVFETRVIVQVLDVNDNPPYCLKYR-YREVLSEGSHPGSYVLTVLATDYDDEPNAKL 3146
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLA 553
+ L N F ++ TG + E ++ L D+ E L
Sbjct: 3147 RFYLTGGKN----EKFSLDKETGVLKTVGQLDRESQAKYILTAHVQDRDKTSWECSSQLE 3202
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
++ ++ + P F Y + +V +GT V ++ +D + Y+ L
Sbjct: 3203 ILISDLN-------DNAPRFSMQSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFL 3255
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVN 670
+ F + SG++T+ L R + MY+ A+ + LS VT V+V D+N
Sbjct: 3256 DSANDH--FVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNVQDIN 3313
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + + ++ G + ++ T+ + +V + I +
Sbjct: 3314 DNPPEFTSKYYFARVPEI--DAVGTEVARVLATSKDT---GVNADVYYTIVGGNEHKKFE 3368
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G + + LD E+ Y +T+ A + GV V I + D NDN P+F A
Sbjct: 3369 IDTKSGVVSIAEQLDYERAKDYFLTIQA-IDGGVPPLTNHATVNITVLDSNDNAPMFSQA 3427
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFI 849
+Y I E++K G ++ + A D D N Y++ G+ ++ F +D +G + +
Sbjct: 3428 SYRASIREDAKAGEKVVQ---VFANDLDSNENGQVSYSIERGDRQKQFTIDSQSGQITVL 3484
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
LDRE+ Y L + A+D G LS+ + I + D NDN P F Q N+ + +E
Sbjct: 3485 A-PLDREQIASYVLEVHAKDNGIPTLSNYVIVNIEVIDANDNPPLFAQ---NNYTTVVQE 3540
Query: 908 TKLNGTA 914
K G A
Sbjct: 3541 DKPLGYA 3547
Score = 101 bits (243), Expect = 1e-19
Identities = 107/375 (28%), Positives = 162/375 (43%), Gaps = 56/375 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++ +GT + K++A D D G+N +IRYEF +FVI+ G
Sbjct: 3224 LPEDVEVGTLVTKVHATDDDIGINRKIRYEFLDSA--------------NDHFVISPDSG 3269
Query: 1000 HVIVARSLPPESEFRLNIS--ALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V +A+ L E++ N+S A+D G L+ + V V+D+ND+ P F +Y V
Sbjct: 3270 IVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVP 3329
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V AT D G NA++ Y I + FEI +GV+S+ +LD E
Sbjct: 3330 EIDAVGTEVARVLATSKDTGVNADVYYTIVGGNEHKKFEIDTKSGVVSIAEQLDYERAKD 3389
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y LT+ A D G D NDN+ P + S
Sbjct: 3390 YFLTIQAID-GGVPPLTNHATVNITVLDSNDNA--------------PMFSQAS------ 3428
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSST 1235
Y+A+I E+A G V +VFAND D N NG + YS+ + Q+ + S S
Sbjct: 3429 ------YRASIREDAKAGEKVVQVFANDLD--SNENGQVSYSIERGDRQKQFTIDSQSGQ 3480
Query: 1236 AILMV-----TVADVPDEVEMSDKPV-FISRYYELEIE---ENVNAPVELVSLNLTEHYE 1286
++ +A EV D + +S Y + IE N N P+ + T E
Sbjct: 3481 ITVLAPLDREQIASYVLEVHAKDNGIPTLSNYVIVNIEVIDANDNPPLFAQNNYTTVVQE 3540
Query: 1287 NFKMRYYILNENDTD 1301
+ + Y +L TD
Sbjct: 3541 DKPLGYAVLKFTVTD 3555
Score = 100 bits (239), Expect = 4e-19
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 9/168 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A +D GV A + Y ++ GN+ K F +D+ +G + + ++LD + +A + L +QA
Sbjct: 3343 ATSKDTGVNADVYYTIVGGNEHKKFEIDTKSGVVSIAEQLDYE-----RAKDYFLTIQAI 3397
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P T A V I +LD NDN P F Y SI E+ G V+QV A D D ENG
Sbjct: 3398 DGGVPPLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENG 3457
Query: 340 EFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ +Y ++ D + F+ID +SG +TV LDRE +S ++V+AK+
Sbjct: 3458 QVSYSIERGDRQKQFTIDSQSGQITV--LAPLDREQIASYVLEVHAKD 3503
Score = 92.3 bits (219), Expect = 9e-17
Identities = 125/548 (22%), Positives = 235/548 (42%), Gaps = 40/548 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F V VT+ D ND+ P F+ S + + + + +GT + +V A+D D G+N + Y +
Sbjct: 1627 NFARVLVTVHDHNDHAPTFI-SEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSM- 1684
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLAVVTIE 558
TS + + F I+P+ GT+ VA L + L V+A+D +P+ + +
Sbjct: 1685 -TSG-NVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDH-GSPALSN----SIPVH 1737
Query: 559 VTRGTKGNKPDIPDFM--GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
V N P P F+ GA + N IG+ V I +A + + ++++ G
Sbjct: 1738 VMVTMADNAP--PRFVRSGAELAAEIYENEEIGSFVKHI---EARSTSSLQFEIVSG-NI 1791
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G F + +GVI+ + L + Y+ ++A + S N VHV+D ND
Sbjct: 1792 GEAFFINPSTGVISTQERLDYEDVKFYNL-SIAATSMSGASAQCNVIVHVLDRNDNAPQF 1850
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI------ 730
++ ++ + S G+ + T+ + + D+ +++
Sbjct: 1851 VQAVYTGQVSEAA--SIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVEELPRKFFH 1908
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ G I T LD E ++ V +++ K +S +V I + D ND PP F+
Sbjct: 1909 IDSSTGAIRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQ 1968
Query: 790 ATYEG-FIMENSKIGTEIKMD-NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ Y ++ K +K++ + +T A +L + G + FD+D +G +
Sbjct: 1969 SDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQSGALT 2028
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
++ + KK Y L + A D G SS A++ I + +++N Q E +
Sbjct: 2029 V--NNPENMKK-SYLLHVRASD-GKYSSVAQVNIKVA-KSENSGLVFQKEVYEGTVVENS 2083
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLI-PENIPIGTTIIKLNALDLDSGLNGQI 966
TK++ A ++ + +F+I P + I TT I+ + +D ++
Sbjct: 2084 TKVSTVAVLNVLGSALNEHVVFSILNPTEMFVIGPTSGAISTTGIRFDRETID---KYEL 2140
Query: 967 RYEFNSEV 974
E NS+V
Sbjct: 2141 IVEANSQV 2148
Score = 91.9 bits (218), Expect = 1e-16
Identities = 122/463 (26%), Positives = 199/463 (42%), Gaps = 71/463 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ ENI GT+I+K+ A D D G NG++RY F S++ E+ F I+ G
Sbjct: 2910 VAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIG-----------ELANVFTIDAYTG 2958
Query: 1000 HV--IVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFK--KTWYNFN 1053
+ +V + E++ + A D GN SV V +KD ND+ F ++ Y
Sbjct: 2959 WISSLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQAT 3018
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V+E V+ ++ D D N L ++I D F I TG + V LDRET
Sbjct: 3019 VKEDALPGTVVVELTTVDKDTELNTALDFYIISGDPRSQFAIRS-TGQVYVAKALDRETR 3077
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
D+Y L VV D DVNDN P Y L++++ E +H
Sbjct: 3078 DRYELLVVGTDG----KFVFETRVIVQVLDVNDNPP--YC----LKYRYREVLSEGSHPG 3127
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ--RKNQ------- 1224
V+ + E NA + + N+ + G +L ++ Q R++Q
Sbjct: 3128 SYVLTVLATDYDDEPNAKLRFYLTG-GKNEKFSLDKETG-VLKTVGQLDRESQAKYILTA 3185
Query: 1225 --QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
Q+ S ++ L + ++D+ D + P F + Y + E+V + ++ T
Sbjct: 3186 HVQDRDKTSWECSSQLEILISDLND-----NAPRFSMQSYSATLPEDVEVGTLVTKVHAT 3240
Query: 1283 EH--YENFKMRYYILNE-NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ N K+RY L+ ND FVI P +G + L + DRE K Y V ++A Q
Sbjct: 3241 DDDIGINRKIRYEFLDSAND-----HFVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQG 3295
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
+ +L + + ++V ++D+NDN P+FT+
Sbjct: 3296 -TPQLSSVTF----------------LIVNVQDINDNPPEFTS 3321
Score = 90.6 bits (215), Expect = 3e-16
Identities = 118/474 (24%), Positives = 207/474 (43%), Gaps = 46/474 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ-R 501
V V + +LD ND P F + Y S+ A GT + ++ A D D G N + Y ++ R
Sbjct: 2359 VLVSILVLDVNDCPPEFSQDS-YNISISEAALFGTELLRLVARDNDTGINSKIRYAIENR 2417
Query: 502 TSNL---TITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQ--PANPSERRYSLAV 554
T++ F ++P G V + S E H V A D+ P+ S L V
Sbjct: 2418 TADELGENTLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVAMDRGVPSLSSTAHVWLTV 2477
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+ + + P P F + Y ++ G V + +D +D + G
Sbjct: 2478 IDMN-------DNP--PKFEQSSYNCFLSEEAERGQFVTVVSASDPDLLDDKLVYTIVGG 2528
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+ +++++ +G+IT+++ + + V++ + S + ++ N
Sbjct: 2529 NDQQTYSIDQSTGIITLIN-MQNFADDKMTLLNVSVSDGVYTSFA-RIKIEILPANRHHP 2586
Query: 675 VLLKGAHSPII-FHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L +P++ V EN G + + T+ +G G + + I N + + I
Sbjct: 2587 KFL----NPVVEVSVLENQLPGKLVTSVLATDKD--FGE-YGTIEYSI-NSDYLKEFFEI 2638
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
E+G I T+K LDREK ++ + V+A G +G V + + DENDN PVF
Sbjct: 2639 DRENGDIVTKKSLDREKHKLFEIPVMASDGGGK---SGFVIVRVKVTDENDNSPVFLLKE 2695
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDENTGVVK 847
Y+ I N + + +KA DADEG A +Y++F E K +F ++ +TG V
Sbjct: 2696 YKASIYGNLTLNSAFLK---VKALDADEGDAAKIIYSIFEPQNSEIKNIFGINPDTGAV- 2751
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAEL---IIMIGDENDNKPEFNQIEE 898
F+ S + ++L + A+D G S ++ I ++G E D P F + E+
Sbjct: 2752 FLKKSAKPWETQPFQLFVRAQDKGLASHHVDVPVEIYIMGPE-DIPPLFERKED 2804
Score = 87.4 bits (207), Expect = 3e-15
Identities = 117/464 (25%), Positives = 190/464 (40%), Gaps = 38/464 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V +T++D NDN P F S+ Y + A+ G + V A DPDL + +V
Sbjct: 2467 LSSTAHVWLTVIDMNDNPPKFEQSS-YNCFLSEEAERGQFVTVVSASDPDLLDDKLVYTI 2525
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY-SLAVVTI 557
+ T + I+ +TG +++ + S S+ Y S A + I
Sbjct: 2526 VGGNDQQT----YSIDQSTGIITLINMQNFADDKMTLLNVS-----VSDGVYTSFARIKI 2576
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYE 615
E+ + + P F+ E V N G V + D E + Y + Y
Sbjct: 2577 EILPANRHH----PKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSINSDYL 2632
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ F ++ +G I L R +++ +A V V V D ND V
Sbjct: 2633 KEF-FEIDRENGDIVTKKSLDREKHKLFEIPVMASDGGGKSGFVI-VRVKVTDENDNSPV 2690
Query: 676 -LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIA 733
LLK + I ++ NSA + + + G+ + + Q ++ + I
Sbjct: 2691 FLLKEYKASIYGNLTLNSAFLKV-----KALDADEGDAAKIIYSIFEPQNSEIKNIFGIN 2745
Query: 734 ED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
D G +F +K + +++ V A+ +KG+ S V IYI D PP+FE
Sbjct: 2746 PDTGAVFLKKSAKPWETQPFQLFVRAQ-DKGLASHHVDVPVEIYIMGPEDIPPLFERKED 2804
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGD 851
+ F+ E S IGT I + TN+ L G + F VD T V G
Sbjct: 2805 KFFVSETSTIGTPITRLRTV------TNTNSTVTCRLVSAGDDFPFAVDPKTCRVTLSG- 2857
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+LDRE K Y + ++A L++ AE+ + + DEND+ P+F
Sbjct: 2858 NLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKF 2901
Score = 86.6 bits (205), Expect = 5e-15
Identities = 83/321 (25%), Positives = 137/321 (42%), Gaps = 25/321 (7%)
Query: 838 DVDENTGVVKF--IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD-ENDNKPEFN 894
DV+ T V K D + +KI Y+ A D +S ++ ++ + + + K +N
Sbjct: 3227 DVEVGTLVTKVHATDDDIGINRKIRYEFLDSANDHFVISPDSGIVTLAKPLDRETKAMYN 3286
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
S + + T + F I+ V+ N + +PE +GT + ++
Sbjct: 3287 V----SIQAMDQGTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVL 3342
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SE 1012
A D+G+N + Y E K+ F I+ + G V +A L E +
Sbjct: 3343 ATSKDTGVNADVYYTI------------VGGNEHKK-FEIDTKSGVVSIAEQLDYERAKD 3389
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L I A+DGG L ++ +V + V D ND+ P+F + Y ++ E + +V A
Sbjct: 3390 YFLTIQAIDGGVPPLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFAN 3449
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D +N ++Y I+ D F I +G ++V LDRE Y+L V A+DNG
Sbjct: 3450 DLDSNENGQVSYSIERGDRQKQFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNG-IPT 3508
Query: 1131 XXXXXXXXXXXXDVNDNSPKF 1151
D NDN P F
Sbjct: 3509 LSNYVIVNIEVIDANDNPPLF 3529
Score = 83.8 bits (198), Expect = 3e-14
Identities = 54/177 (30%), Positives = 92/177 (51%), Gaps = 12/177 (6%)
Query: 217 PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
PI + +T+ L+S D F++D + L LD + + +++++ V
Sbjct: 2817 PITRLRTVTNTNSTVTCRLVSAGDDFPFAVDPKTCRVTLSGNLDREVK-----DSYMIGV 2871
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A ++P TA A + +++LD ND+ P+FE + Y+I++ EN+ G S+L+V+A D D G
Sbjct: 2872 LAETDSSPPLTALAEITLQVLDENDHAPKFESNPYSIAVAENIEEGTSILKVVAHDNDLG 2931
Query: 337 ENGEFTYQLDDPKG----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NP 388
NGE Y G F+ID +GW++ Q LD+E + +V A + NP
Sbjct: 2932 SNGEVRYSFGSDIGELANVFTIDAYTGWISSLVQ--LDKEQQPEYKFQVIATDNGNP 2986
Score = 83.8 bits (198), Expect = 3e-14
Identities = 97/385 (25%), Positives = 166/385 (43%), Gaps = 47/385 (12%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
+ + + D+ND+ P F Y+ + E ++ KV ATD D G N + Y S D
Sbjct: 3201 LEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLDSAND 3260
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F ISP +G++++ LDRET+ Y +++ A D G D+NDN P+
Sbjct: 3261 -HFVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNVQ-DINDNPPE 3318
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
F + + + PE D + E ++ K T NA + T+ + I
Sbjct: 3319 FTS--KYYFARVPEIDAVGT---EVARVLATSKDT-GVNADVYYTIVGGNEHKKFEIDTK 3372
Query: 1211 NGLILYSLP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
+G++ + +R L G+P L++ A + +TV D D + P+F
Sbjct: 3373 SGVVSIAEQLDYERAKDYFLTIQAIDGGVPPLTNHATVNITVLDSND-----NAPMFSQA 3427
Query: 1261 YYELEIEENVNAPVELVSL--NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
Y I E+ A ++V + N + EN ++ Y I D ++ F ID ++G + ++
Sbjct: 3428 SYRASIREDAKAGEKVVQVFANDLDSNENGQVSYSI---ERGDRQKQFTIDSQSGQITVL 3484
Query: 1319 RSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
DRE +Y + V A+ ++ + ++ Y V V + + D NDN P
Sbjct: 3485 APLDREQIASYVLEVHAK----------------DNGIPTLSNY-VIVNIEVIDANDNPP 3527
Query: 1379 KFTNGNRPLVTAIPTTAPFGYQVMQ 1403
F N T + P GY V++
Sbjct: 3528 LFAQNN--YTTVVQEDKPLGYAVLK 3550
Score = 83.0 bits (196), Expect = 6e-14
Identities = 98/373 (26%), Positives = 162/373 (43%), Gaps = 37/373 (9%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFAVEERSGV 628
P F YE V + + S+ ++ DA ++ Y E+ FAV SGV
Sbjct: 206 PLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSFAEKTEQ---FAVHPVSGV 262
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-----TVHVVDVNDERGVLLKGAHSP 683
+T+ L RP+Y+ A A + A T+HV VN + H P
Sbjct: 263 VTLTRPLRYVERPLYELTVQARDRGALYRMTPRASNARLTIHVRQVN-LHAPEISVRHLP 321
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV---TDDIAIAEDGTIFT 740
I N+ AI ++ + +G ++A D + + +I
Sbjct: 322 EILE-HSNADTYAIVRVLDRDTGP---HGEIASLEIVAGDPDGHFRVRPLPTPGEYSIQV 377
Query: 741 QKPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
K LDRE Y +T+ A ++G V +++ D NDN P+F Y+ + E
Sbjct: 378 LKLLDREAAPQGYNLTLRA-VDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPET 436
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVKFIGDSLDREK 857
+ + + + +K +DAD+G NAL + G EG E F ++ +TG++ + LD E
Sbjct: 437 APVNSPVIR---LKVSDADQGKNALVFLEIVGGNEGGE-FYINADTGML-YTAVPLDAET 491
Query: 858 KIMYKLSLVARDTGGL----SSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
K Y L++ A D G S A++ I + D NDN PEF E S++ ++ + N
Sbjct: 492 KAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDTNDNDPEF----EKSEMLVYLDE--NEP 545
Query: 914 AGFTIIEVKPKNK 926
AG ++ +V ++K
Sbjct: 546 AGTSVCKVVARDK 558
Score = 83.0 bits (196), Expect = 6e-14
Identities = 117/492 (23%), Positives = 207/492 (42%), Gaps = 77/492 (15%)
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPE-------NIPIGTTIIKLNALDLDSGLNG 964
G +GF I+ VK D + P+FL+ E N+ + + +K+ ALD D G
Sbjct: 2670 GKSGFVIVRVK-----VTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAA 2724
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP-ESE-FRLNISALDG 1022
+I Y ++ P + E+K F IN G V + +S P E++ F+L + A D
Sbjct: 2725 KIIYS----IFEPQNS------EIKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDK 2774
Query: 1023 GNLNDNISV--RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
G + ++ V +++ D P+F++ F V E + ++ N+ +
Sbjct: 2775 GLASHHVDVPVEIYIMGPEDIPPLFERKEDKFFVSETSTIGTPITRLRTVT---NTNSTV 2831
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
T + + D PF + P T ++++G LDRE +D Y++ V+A +
Sbjct: 2832 TCRLVSAGDDFPFAVDPKTCRVTLSGNLDREVKDSYMIGVLA-ETDSSPPLTALAEITLQ 2890
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI----GTTV 1196
D ND++PKF E + A+ + S++ + + + N + G+ +
Sbjct: 2891 VLDENDHAPKF----ESNPYSIAVAENIEEGT--SILKVVAHDNDLGSNGEVRYSFGSDI 2944
Query: 1197 ---AKVFAND--TDFIGNGNGLILYSLPQRKNQ---QNLGLPSLSSTAILMVTVADVPDE 1248
A VF D T +I + L P+ K Q + G P S ++V + D D
Sbjct: 2945 GELANVFTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDN 3004
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTF 1306
Y+ ++E+ +V L + N + +YI++ D R F
Sbjct: 3005 PSAFSS---AESGYQATVKEDALPGTVVVELTTVDKDTELNTALDFYIIS---GDPRSQF 3058
Query: 1307 VIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKV 1366
I G +Y+ ++ DRE +D YE++V V D G ++ +V
Sbjct: 3059 AI-RSTGQVYVAKALDRETRDRYELLV-----------------VGTD---GKFVFETRV 3097
Query: 1367 VVRIKDVNDNSP 1378
+V++ DVNDN P
Sbjct: 3098 IVQVLDVNDNPP 3109
Score = 81.0 bits (191), Expect = 2e-13
Identities = 90/332 (27%), Positives = 144/332 (43%), Gaps = 32/332 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPR 136
A+ V V + D+NDN PIF++ PY+ V G+ + G + + + +
Sbjct: 2154 AHTIVNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKK 2213
Query: 137 GL-TIFKDIRAFDRD--KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
G +FK R K N + Y ++ DG + S V + KV+D
Sbjct: 2214 GHGELFKVNRKTGEISLKQNLEGHNREYQLMIAAYDGGISPCSVEISVNV--KVIDRSMP 2271
Query: 194 --DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
DK+F + +H + +I + + L Y + GND + F+LD G
Sbjct: 2272 VFDKQFYTDSVLESIEVHSPLAL-----SIQAESPLNRKLIYSITKGNDFEEFALDFNTG 2326
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+++ ELD + Q + L V+A+ + + A+ V I +LD+ND PEF D Y
Sbjct: 2327 VIYVVDELDYE-----QKKQYELTVRATDSVSGVY-AEVLVSILVLDVNDCPPEFSQDSY 2380
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD----DPKG-----AFSIDPRSGWLT 362
NISI E G +L+++A D D G N + Y ++ D G F +DP G +
Sbjct: 2381 NISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGIVY 2440
Query: 363 VRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
++ LD E S V A + PS+ T
Sbjct: 2441 LKRS--LDHETADSHHFTVVAMDRGVPSLSST 2470
Score = 78.6 bits (185), Expect = 1e-12
Identities = 116/464 (25%), Positives = 178/464 (38%), Gaps = 59/464 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E GT I + N D D G N Q+ Y ++ + L V +
Sbjct: 908 FRVSEAALNGTIIFRANTTDADLGENAQVAYSLVTDTSDFRVDRTTGVLTVFGKLDRERQ 967
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + R+ D L VRV V DVND+ P F T Y V E
Sbjct: 968 SSYELRIRATDKNGGNDKGEPDFDNPALYSEALVRVSVDDVNDNAPKFALTSYTVKVRED 1027
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
V+ ++ATD D G + Y F + +++ F I L+G + +LD E +
Sbjct: 1028 VPVWSVIAVIEATDPDEGPGGIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVH 1087
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDN--SPKFYAFDELLEWKHPEADELSNHNFE 1174
LT+VA+D G DVN+N +P F F
Sbjct: 1088 TLTIVAKDKGEPSLSSETILIIEVV-DVNENLHAPVFNDF-------------------- 1126
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTD----------FIGNGNGLILYSLPQRKNQ 1224
V A++ EN P+ T V +V A D D I G+G+ L+S+ N
Sbjct: 1127 ------VISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGDGVGLFSIDDEGNI 1180
Query: 1225 QNLGLPSLSSTAILMVTV-ADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ + + + A +TV A V +S K + Y E+ ++EN N P+ +
Sbjct: 1181 RTKAVLDVEAKAGYWLTVYAQDHGVVPLSSK---LQVYVEV-LDENDNTPLTEQPVYYPS 1236
Query: 1284 HYENFKMRYYILNEN--DTDI---RRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
EN +L D D+ + +F I N Y + + T +I + R
Sbjct: 1237 VLENSPAGVSVLQIRAFDRDVSPQQFSFAITSGNAEGYFL------INSTSGLITTSGR- 1289
Query: 1339 KYSRE--LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
K RE H++ D + +VVV++ DVND+SP F
Sbjct: 1290 KLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVF 1333
Score = 78.2 bits (184), Expect = 2e-12
Identities = 89/358 (24%), Positives = 148/358 (41%), Gaps = 25/358 (6%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKT 1048
F ++ G + V L E ++ L + A D + + V + V DVND P F +
Sbjct: 2319 FALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAEVLVSILVLDVNDCPPEFSQD 2378
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-------PFEISPLTGV 1101
YN ++ EA L ++ A D D G N+ + Y I+ D F + P G+
Sbjct: 2379 SYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGI 2438
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ + LD ET D + TVVA D G D+NDN PKF E +
Sbjct: 2439 VYLKRSLDHETADSHHFTVVAMDRG-VPSLSSTAHVWLTVIDMNDNPPKF----EQSSYN 2493
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND--TDFIGNGNGLILYSLP 1219
++E F V ++ + ++ + T V ND T I G+I
Sbjct: 2494 CFLSEEAERGQF--VTVVSASDPDLLDDKLVYTIVG---GNDQQTYSIDQSTGIITLINM 2548
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK--PVFISRYYELEIEENVNAPVELV 1277
Q + L ++S + + + A + E+ +++ P F++ E+ + EN P +LV
Sbjct: 2549 QNFADDKMTLLNVSVSDGVYTSFARIKIEILPANRHHPKFLNPVVEVSVLEN-QLPGKLV 2607
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ L + + + N ++ F ID NG + +S DRE +E+ V A
Sbjct: 2608 TSVLATDKDFGEYGTIEYSINSDYLKEFFEIDRENGDIVTKKSLDREKHKLFEIPVMA 2665
Score = 77.0 bits (181), Expect = 4e-12
Identities = 101/412 (24%), Positives = 174/412 (42%), Gaps = 45/412 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G +++++ A D D ++ Q +F+ + S +A + YF+IN G +
Sbjct: 1239 ENSPAGVSVLQIRAFDRD--VSPQ---QFSFAI------TSGNA---EGYFLINSTSGLI 1284
Query: 1002 IVA-RSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ R L E+ E L ++ D G L+ V V V DVNDH PVF++ +Y +
Sbjct: 1285 TTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVFEEKFYMVQIPA 1344
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ + L +V A D D G+N + Y I+ F+I P TG+ V + E ++
Sbjct: 1345 SPSLDKPLFQVLAHDQDIGKNGKIQYSIKSGKGKGKFKIHPDTGM--VYSQRGFEAGQEF 1402
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVND--NSPKFYAFDELLEWKHPEADELSNHNFE 1174
+ + A D G D N P F + ++ +E E+D+
Sbjct: 1403 EMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVE--VTESDKAG----- 1455
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
++ + +AT ++ + + + D IG +G +L + QN ++S
Sbjct: 1456 --FLVALMQATDKDGDSLWYDIVEGDTRDEFVIGRDDGNVLLAKQLDWETQNFYNLTISV 1513
Query: 1235 T-------AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE-LVSLNLTEHYE 1286
T L V V D+ D +P Y +EI ENV E ++ L+ + E
Sbjct: 1514 TDGVNEARTSLFVKVIDINDH-----RPELSESIYHVEISENVVEKGEAILQLHAQDLDE 1568
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ K+ Y + N + F +D GT+ L + DRE + + V + Q
Sbjct: 1569 DKKLFYSLHNAQSQASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQ 1620
Score = 76.6 bits (180), Expect = 5e-12
Identities = 109/438 (24%), Positives = 188/438 (42%), Gaps = 39/438 (8%)
Query: 423 DKVGTKTENIEYYDEQ-LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
DK G + +D L S V V++ D NDN P F ++ Y ++ + V +VI
Sbjct: 978 DKNGGNDKGEPDFDNPALYSEALVRVSVDDVNDNAPKFALTS-YTVKVREDVPVWSVIAV 1036
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEAS 539
++A DPD G G++ Y + + F I+ +GT+ + E R H L + A
Sbjct: 1037 IEATDPDEGPGGIIEYSF--SEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAK 1094
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
D+ PS ++ ++ + V + P DF+ + V N + T V Q++ D
Sbjct: 1095 DK-GEPSLSSETILIIEV-VDVNENLHAPVFNDFVISAS---VSENQPLNTLVTQVKAKD 1149
Query: 600 AFE---QNDVSYDLLHGYEEGVPFAVEERSGVIT-VVDDLSRYNRPMYDFEAVALQENA- 654
A + + Y + G G+ F++++ + T V D+ + Y A
Sbjct: 1150 ADPPGGDSRIGYSIRGGDGVGL-FSIDDEGNIRTKAVLDVEA--KAGYWLTVYAQDHGVV 1206
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQI--FHTNMSSIYGN 711
LS V V+D ND + + + P + ENS AG ++ QI F ++S
Sbjct: 1207 PLSSKLQVYVEVLDENDNTPLTEQPVYYPSVL---ENSPAGVSVLQIRAFDRDVSP---- 1259
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQ-KPLDREKRDVYRMTV-IAEFNKGVISGAG 769
F I + + + G I T + LDRE + + + V + + + V+S
Sbjct: 1260 --QQFSFAITSGNAEGYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTT 1317
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+V + ++D ND+ PVFE Y I + + + + A D D G N Y++
Sbjct: 1318 --RVVVQVDDVNDHSPVFEEKFYMVQIPASPSLDKPLFQ---VLAHDQDIGKNGKIQYSI 1372
Query: 830 -FGEGKEMFDVDENTGVV 846
G+GK F + +TG+V
Sbjct: 1373 KSGKGKGKFKIHPDTGMV 1390
Score = 74.9 bits (176), Expect = 2e-11
Identities = 64/206 (31%), Positives = 97/206 (47%), Gaps = 19/206 (9%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G I+K++A+DLDSG NG++RYE K L F +N + G + + ++
Sbjct: 2188 GDVIMKVHAIDLDSGDNGEVRYEL---------KKGHGEL-----FKVNRKTGEISLKQN 2233
Query: 1007 LPPES-EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
L + E++L I+A DGG ++ + V VK ++ PVF K +Y +V E+ L
Sbjct: 2234 LEGHNREYQLMIAAYDGGISPCSVEISVNVKVIDRSMPVFDKQFYTDSVLESIEVHSPLA 2293
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ A+ N L Y I + F + TGV+ V ELD E + +Y LTV A D+
Sbjct: 2294 L--SIQAESPLNRKLIYSITKGNDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDS 2351
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKF 1151
DVND P+F
Sbjct: 2352 --VSGVYAEVLVSILVLDVNDCPPEF 2375
Score = 74.5 bits (175), Expect = 2e-11
Identities = 107/472 (22%), Positives = 209/472 (44%), Gaps = 45/472 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD----LGQNGMVL 496
S V +T+ D ND P F S+ Y ++ + K++A DPD +
Sbjct: 1948 STAKVIITVSDVNDCPPKFQQSD-YNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLR 2006
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
YD+ + F I+ +G ++V ++ + L V ASD + S+A V
Sbjct: 2007 YDIIDGNQ---GQSFDIDSQSGALTVNNPENMKKSYLLHVRASDGKYS------SVAQVN 2057
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I+V + F YE V N ++V + V + V + +L+ E
Sbjct: 2058 IKVAKSENSGLV----FQKEVYEGTVVENSTKVSTVAVLNVLGSALNEHVVFSILNPTEM 2113
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV----TNATVHVVDVNDE 672
F + SG I+ R++R D + ++ N+ + T V V+D+ND
Sbjct: 2114 ---FVIGPTSGAISTTG--IRFDRETIDKYELIVEANSQVPTQRVAHTIVNVTVLDINDN 2168
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + + ++ + G I ++ ++ S G VR+ + +
Sbjct: 2169 CPIFVNLPYYAVVS--VDAQKGDVIMKVHAIDLDS---GDNGEVRYELKKGHGELFKVN- 2222
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G I ++ L+ R+ Y++ +IA ++ G IS + ++++ ++ + + PVF+ Y
Sbjct: 2223 RKTGEISLKQNLEGHNRE-YQL-MIAAYDGG-ISPCSV-EISVNVKVIDRSMPVFDKQFY 2278
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
++E+ ++ + + + + A+ N +Y++ G E F +D NTGV+ ++ D
Sbjct: 2279 TDSVLESIEVHSPLAL-----SIQAESPLNRKLIYSITKGNDFEEFALDFNTGVI-YVVD 2332
Query: 852 SLDREKKIMYKLSLVARDT-GGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
LD E+K Y+L++ A D+ G+ +E + I++ D ND PEF+Q N +
Sbjct: 2333 ELDYEQKKQYELTVRATDSVSGVYAEVLVSILVLDVNDCPPEFSQDSYNISI 2384
Score = 72.5 bits (170), Expect = 8e-11
Identities = 48/157 (30%), Positives = 78/157 (49%), Gaps = 10/157 (6%)
Query: 218 IHAIDQDLGVGATLRYELI-SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+HA D D+G+ +RYE + S ND + S DS G + L K LD + + + + +
Sbjct: 3237 VHATDDDIGINRKIRYEFLDSANDHFVISPDS--GIVTLAKPLDRETKA-----MYNVSI 3289
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
QA P ++ + + + D+NDN PEF +Y + E G V +V+AT KD G
Sbjct: 3290 QAMDQGTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTG 3349
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDR 371
N + Y + + F ID +SG +++ Q +R
Sbjct: 3350 VNADVYYTIVGGNEHKKFEIDTKSGVVSIAEQLDYER 3386
Score = 72.1 bits (169), Expect = 1e-10
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 9/167 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D A LR+ L G + K FSLD G L +LD +++ ++L
Sbjct: 3135 ATDYDDEPNAKLRFYLTGGKNEK-FSLDKETGVLKTVGQLDRESQAK-----YILTAHVQ 3188
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ +++EI + DLNDN P F + Y+ ++ E++ G V +V ATD D G N
Sbjct: 3189 DRDKTSWECSSQLEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVHATDDDIGINR 3248
Query: 340 EFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ Y+ LD F I P SG +T+ LDRE + + + A +
Sbjct: 3249 KIRYEFLDSANDHFVISPDSGIVTLAKP--LDRETKAMYNVSIQAMD 3293
Score = 71.3 bits (167), Expect = 2e-10
Identities = 54/174 (31%), Positives = 86/174 (49%), Gaps = 13/174 (7%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F + A D DL + L Y ++ GND++ +S+D G + L ++ ++ +
Sbjct: 2505 FVTVVSASDPDL-LDDKLVYTIVGGNDQQTYSIDQSTGIITL-----INMQNFADDKMTL 2558
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V S + + T+ AR++IE+L N + P+F +S++EN G V V+ATDK
Sbjct: 2559 LNVSVS---DGVYTSFARIKIEILPANRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDK 2615
Query: 334 DQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D GE G Y + D K F ID +G + + LDRE H + V A +
Sbjct: 2616 DFGEYGTIEYSINSDYLKEFFEIDRENGDIVTKKS--LDREKHKLFEIPVMASD 2667
Score = 70.5 bits (165), Expect = 3e-10
Identities = 90/325 (27%), Positives = 138/325 (42%), Gaps = 24/325 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLIAPI-GPSLTIPLTVPR---- 136
V V ++DVNDN P F T Y V V E P A I P GP I +
Sbjct: 1001 VRVSVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEEMES 1060
Query: 137 -GLTIFKDIRAFDRD--KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
G + R K + VH + D G +L S +L+ +V+D +
Sbjct: 1061 EGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSE---TILIIEVVDVNEN 1117
Query: 194 --DKEFQ-LVIMASGKRIHKEILFPEPIHAIDQDL-GVGATLRYELISGNDRKLFSLDSV 249
F VI AS + A D D G + + Y + G+ LFS+D
Sbjct: 1118 LHAPVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGDGVGLFSIDD- 1176
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G++ + LD++A+ + L V A +++ +V +E+LD NDN P E
Sbjct: 1177 EGNIRTKAVLDVEAKAG-----YWLTVYAQDHGVVPLSSKLQVYVEVLDENDNTPLTEQP 1231
Query: 310 FYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
Y S++EN P G SVLQ+ A D+D + F + +G F I+ SG +T +
Sbjct: 1232 VYYPSVLENSPAGVSVLQIRAFDRDVSPQQFSFAITSGNAEGYFLINSTSGLITTSGRK- 1290
Query: 369 LDREAHSSLRMKVYAKETNPSVVGT 393
LDRE + ++V ++ V+ +
Sbjct: 1291 LDRENQAEHILEVTVRDDGRPVLSS 1315
Score = 70.5 bits (165), Expect = 3e-10
Identities = 94/409 (22%), Positives = 180/409 (44%), Gaps = 32/409 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E GT +++L A D D+G+N +IRY + +L + L++ F ++ G
Sbjct: 2384 ISEAALFGTELLRLVARDNDTGINSKIRYAIENRT---ADELGENTLDL---FHVDPEEG 2437
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V + RSL E+ + A+D G +L+ V + V D+ND+ P F+++ YN +
Sbjct: 2438 IVYLKRSLDHETADSHHFTVVAMDRGVPSLSSTAHVWLTVIDMNDNPPKFEQSSYNCFLS 2497
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + V A+D D + L Y I + + I TG++++ + +DK
Sbjct: 2498 EEAERGQFVTVVSASDPDL-LDDKLVYTIVGGNDQQTYSIDQSTGIITLI-NMQNFADDK 2555
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
L V+ +G N + PKF + ++E E ++L S
Sbjct: 2556 MTLLNVSVSDG---VYTSFARIKIEILPANRHHPKF--LNPVVEVSVLE-NQLPGKLVTS 2609
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG-LILYSLPQRKNQQNLGLPSLSS 1234
V+ E I ++ + + I NG ++ R+ + +P ++S
Sbjct: 2610 VL---ATDKDFGEYGTIEYSINSDYLKEFFEIDRENGDIVTKKSLDREKHKLFEIPVMAS 2666
Query: 1235 ----TAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV---NAPVELVSLNLTEHYEN 1287
+ ++ V DE + S PVF+ + Y+ I N+ +A +++ +L+ E +
Sbjct: 2667 DGGGKSGFVIVRVKVTDENDNS--PVFLLKEYKASIYGNLTLNSAFLKVKALDADEG-DA 2723
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
K+ Y I +++I+ F I+P G ++L +S +++ VRA+
Sbjct: 2724 AKIIYSIFEPQNSEIKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQ 2772
Score = 69.3 bits (162), Expect = 8e-10
Identities = 74/321 (23%), Positives = 141/321 (43%), Gaps = 25/321 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-----KAFIFLIAPIGPS 127
G+ +S+ L V V + D NDN P+ Y+ +V E +P G +AF ++P S
Sbjct: 1204 GVVPLSSKLQVYVEVLDENDNTPLTEQPVYYPSVLENSPAGVSVLQIRAFDRDVSPQQFS 1263
Query: 128 LTIPLTVPRGLTIFKDIRAF---DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
I G + K + N H V+ DDG L S+ + V+ +
Sbjct: 1264 FAITSGNAEGYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQV 1323
Query: 185 RKVLDYD-AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
V D+ +++F +V + + + K + + A DQD+G ++Y + SG +
Sbjct: 1324 DDVNDHSPVFEEKFYMVQIPASPSLDKPLF---QVLAHDQDIGKNGKIQYSIKSGKGKGK 1380
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL---N 300
F + G ++ ++ + E F + ++A+ P ++ QAR+ +++++ +
Sbjct: 1381 FKIHPDTGMVYSQRGFEAGQE-------FEMIIRATDEGEPPRSHQARISVQVVETPKDS 1433
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
N P F+ ++ + E+ GF V + ATDKD G++ + D + F I G
Sbjct: 1434 PNPPVFKSLNQSVEVTESDKAGFLVALMQATDKD-GDSLWYDIVEGDTRDEFVIGRDDGN 1492
Query: 361 LTVRNQTVLDREAHSSLRMKV 381
+ + Q LD E + + +
Sbjct: 1493 VLLAKQ--LDWETQNFYNLTI 1511
Score = 69.3 bits (162), Expect = 8e-10
Identities = 51/168 (30%), Positives = 82/168 (48%), Gaps = 12/168 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+HA QDL L Y L + + ++F +DS+ G++ L + LD + +Q + +L
Sbjct: 1561 LHA--QDLDEDKKLFYSLHNAQSQASLQIFHVDSLTGTITLNEALDRET---IQEH--IL 1613
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V P K ARV + + D ND+ P F + + E P G +V+QV+A D+D
Sbjct: 1614 TVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRD 1673
Query: 335 QGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
+GEN + +Y + FSIDP G + V + L + L +K
Sbjct: 1674 RGENAQLSYSMTSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVK 1721
Score = 66.9 bits (156), Expect = 4e-09
Identities = 110/424 (25%), Positives = 178/424 (41%), Gaps = 52/424 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E PIGT ++++ A+D D G N Q+ Y S V F I+ G +
Sbjct: 1656 ETSPIGTAVVQVIAIDRDRGENAQLSYSMTSG-------------NVGNVFSIDPDLGTI 1702
Query: 1002 IVARSLP--PESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VAR L SE+ L + A D G+ L+++I V V V ++ P F ++ E
Sbjct: 1703 RVARELDLATASEYILLVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRSGAELAAEI- 1761
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
Y +G + ++L + I + F I+P TGV+S LD E Y
Sbjct: 1762 -YENEEIGSF-VKHIEARSTSSLQFEIVSGNIGEAFFINPSTGVISTQERLDYEDVKFYN 1819
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA---FDELLEWKHPEADELSNHNFE 1174
L++ A D NDN+P+F ++ E + S ++
Sbjct: 1820 LSIAAT---SMSGASAQCNVIVHVLDRNDNAPQFVQAVYTGQVSEAASIGSLVFSANSTS 1876
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL-------YSLPQ---RKNQ 1224
S ++I A E NA + + + I + G I ++P+
Sbjct: 1877 SPLVIKAEDADSELNALLNYDIVEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKV 1936
Query: 1225 QNLGLPSLS--STAILMVTVADV---PDEVEMSDKPVFISRYYELEIEENVN-APVELVS 1278
+LG P LS STA +++TV+DV P + + SD + L +NV +E
Sbjct: 1937 SDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVL----LPTWKNVAVVKLEAHD 1992
Query: 1279 LNLTEHYENF-KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ T + N +RY I++ N ++F ID ++G L V +P+ +K +Y + VRA
Sbjct: 1993 PDSTSAFTNQPSLRYDIIDGNQ---GQSFDIDSQSGAL-TVNNPE-NMKKSYLLHVRASD 2047
Query: 1338 QKYS 1341
KYS
Sbjct: 2048 GKYS 2051
Score = 66.1 bits (154), Expect = 7e-09
Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 12/145 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D G T+ Y + S ++ F +D NG + +K LD + +H L F + V AS
Sbjct: 2612 ATDKDFGEYGTIEYSINSDYLKEFFEIDRENGDIVTKKSLDRE-KHKL----FEIPVMAS 2666
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
K+ V +++ D NDN P F + Y SI NL + L+V A D D+G+
Sbjct: 2667 DGGG--KSGFVIVRVKVTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAA 2724
Query: 340 EFTYQLDDP-----KGAFSIDPRSG 359
+ Y + +P K F I+P +G
Sbjct: 2725 KIIYSIFEPQNSEIKNIFGINPDTG 2749
Score = 65.7 bits (153), Expect = 9e-09
Identities = 103/459 (22%), Positives = 187/459 (40%), Gaps = 35/459 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL-GQNGMVLYDLQRTS 503
+EV ++ N + PVF + S+ N + T++ +VKA D D G + + Y ++
Sbjct: 1109 IEVVDVNENLHAPVF-NDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGD 1167
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ + S N T +V + G + L V A D P + + V ++ T
Sbjct: 1168 GVGLFS-IDDEGNIRTKAVLDVEAKAG-YWLTVYAQDHGVVPLSSKLQVYVEVLDENDNT 1225
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVPFAV 622
+ + Y V N G SV QIR D S+ + G EG F +
Sbjct: 1226 PLTEQPV-------YYPSVLENSPAGVSVLQIRAFDRDVSPQQFSFAITSGNAEGY-FLI 1277
Query: 623 EERSGVITVVD-DLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGA 680
SG+IT L R N+ + E + LS T V V DVND
Sbjct: 1278 NSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVND--------- 1328
Query: 681 HSPII---FHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDG 736
HSP+ F++ + A ++ + ++ G G +++ I + + + G
Sbjct: 1329 HSPVFEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKSGKGKGKFKIHPDTG 1388
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+++Q+ + + + E A I + ++ NPPVF+ +
Sbjct: 1389 MVYSQRGFEAGQEFEMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEV 1448
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E+ K G + +++ATD D ++L+ + G+ ++ F + + G V + LD E
Sbjct: 1449 TESDKAGFLVA---LMQATDKD--GDSLWYDIVEGDTRDEFVIGRDDGNV-LLAKQLDWE 1502
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ Y L++ D G + L + + D ND++PE ++
Sbjct: 1503 TQNFYNLTISVTD-GVNEARTSLFVKVIDINDHRPELSE 1540
Score = 63.7 bits (148), Expect = 4e-08
Identities = 70/275 (25%), Positives = 118/275 (42%), Gaps = 17/275 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTI 130
G Q+S+ + V ++D+NDN P F Y V E+ G + L G + +
Sbjct: 3295 GTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADV 3354
Query: 131 PLTVPRGLTIFK---DIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
T+ G K D ++ ++ + + ++ + D G L ++H V +
Sbjct: 3355 YYTIVGGNEHKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQAIDGGVPPL-TNHATVNIT 3413
Query: 185 RKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
VLD + F Q AS + K + A D D + Y + G+ +K
Sbjct: 3414 --VLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENGQVSYSIERGDRQKQ 3471
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F++DS +G + + LD + Q ++VL+V A P + V IE++D NDN
Sbjct: 3472 FTIDSQSGQITVLAPLDRE-----QIASYVLEVHAKDNGIPTLSNYVIVNIEVIDANDNP 3526
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P F + Y + E+ P G++VL+ TD D N
Sbjct: 3527 PLFAQNNYTTVVQEDKPLGYAVLKFTVTDADAEPN 3561
Score = 61.7 bits (143), Expect = 2e-07
Identities = 66/224 (29%), Positives = 93/224 (41%), Gaps = 32/224 (14%)
Query: 1002 IVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
++ R P+ + L + A+D G SV V + D+ND+ P+F Y+ V E
Sbjct: 380 LLDREAAPQG-YNLTLRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAP 438
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ ++ +DAD G+NA + I + F I+ TG+L LD ET+ Y LT
Sbjct: 439 VNSPVIRLKVSDADQGKNALVFLEIVGGNEGGEFYINADTGMLYTAVPLDAETKAFYTLT 498
Query: 1120 VVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
V A D G D NDN P+F E E+
Sbjct: 499 VSAVDQGNAGTRKQSSAKVKIYVIDTNDNDPEF------------EKSEML--------- 537
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK 1222
VY ++EN P GT+V KV A D D N I YS+ K
Sbjct: 538 --VY---LDENEPAGTSVCKVVARDKD--SGENAYISYSIDNIK 574
Score = 60.5 bits (140), Expect = 3e-07
Identities = 88/410 (21%), Positives = 168/410 (40%), Gaps = 45/410 (10%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA---PIGPSLTIPLT 133
++A +T+ + D ND+ P F PY + V E G + + ++A +G + + +
Sbjct: 2881 LTALAEITLQVLDENDHAPKFESNPYSIAVAENIEEGT-SILKVVAHDNDLGSNGEVRYS 2939
Query: 134 VPRGLTIFKDIRAFDR-----------DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
+ ++ D DK P + HF+ S
Sbjct: 2940 FGSDIGELANVFTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNPRHFSRTS------ 2993
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEIL---FPEPIHAIDQDLGVGATLRYELISGN 239
+L K+ DY+ F + ++ L + +D+D + L + +ISG+
Sbjct: 2994 VLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVELTTVDKDTELNTALDFYIISGD 3053
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
R F++ S G +++ K LD + + + L V + +T RV +++LD+
Sbjct: 3054 PRSQFAIRST-GQVYVAKALDRETR-----DRYELLVVGTDGKFVFET---RVIVQVLDV 3104
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-AFSIDPRS 358
NDN P Y + E G VL V+ATD D N + + L K FS+D +
Sbjct: 3105 NDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKLRFYLTGGKNEKFSLDKET 3164
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP---LE 415
G L Q LDRE+ + + + ++ + + ++ S ++ + L NAP ++
Sbjct: 3165 GVLKTVGQ--LDRESQAKYILTAHVQDRDKT---SWECSSQL-EILISDLNDNAPRFSMQ 3218
Query: 416 KTTYVFPD--KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSN 463
+ P+ +VGT + D+ + + LD+ +++ V P +
Sbjct: 3219 SYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLDSANDHFVISPDS 3268
Score = 58.4 bits (135), Expect = 1e-06
Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 21/184 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G +L Y+++ G+ R F + +G++ L K+LD + + N + L +
Sbjct: 1461 MQATDKD---GDSLWYDIVEGDTRDEFVIGRDDGNVLLAKQLDWETQ-----NFYNLTIS 1512
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQG 336
+ N +T+ + ++++D+ND+ PE Y++ I EN + G ++LQ+ A D D
Sbjct: 1513 VTDGVNEARTS---LFVKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHAQDLD-- 1567
Query: 337 ENGEFTYQLDDPKG-----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
E+ + Y L + + F +D +G +T+ LDRE + V K+
Sbjct: 1568 EDKKLFYSLHNAQSQASLQIFHVDSLTGTITLNE--ALDRETIQEHILTVMVKDQGTPAK 1625
Query: 392 GTFA 395
FA
Sbjct: 1626 RNFA 1629
Score = 58.4 bits (135), Expect = 1e-06
Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 17/161 (10%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A D D + A L Y+++ RK F +DS G++ LD + Q N
Sbjct: 1878 PLVIKAEDADSELNALLNYDIVEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFN---- 1933
Query: 275 QVQASQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V+ S L P +++ A+V I + D+ND P+F+ YN +++ LP +V V
Sbjct: 1934 -VKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVL--LPTWKNVAVVKLEA 1990
Query: 333 KDQGENGEFTYQ-------LDDPKG-AFSIDPRSGWLTVRN 365
D FT Q +D +G +F ID +SG LTV N
Sbjct: 1991 HDPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQSGALTVNN 2031
Score = 58.0 bits (134), Expect = 2e-06
Identities = 91/372 (24%), Positives = 149/372 (40%), Gaps = 38/372 (10%)
Query: 991 YFVINERHGHVIVARSLPPESEFRLNISAL----DGGN----LNDNISVRVFVKDVNDHF 1042
+ ++ R GHV V + ++ L I A DG N L +V V + D ND
Sbjct: 147 FLLLRTRTGHVDVLNR-ERKDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLN 205
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
P+F T Y V E + + KV A DAD G N + Y ++ F + P++GV+
Sbjct: 206 PLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSF--AEKTEQFAVHPVSGVV 263
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH 1162
++ L Y LTV ARD G V +A E+
Sbjct: 264 TLTRPLRYVERPLYELTVQARDRGALYRMTPRASNARLTIHV--RQVNLHA-PEISVRHL 320
Query: 1163 PEADELSNHNFESVMMIPVYKATIEENAPIGTTVA-KVFANDTD---------FIGNGNG 1212
PE E SN + +++ + + P G + ++ A D D G +
Sbjct: 321 PEILEHSNADTYAIV-----RVLDRDTGPHGEIASLEIVAGDPDGHFRVRPLPTPGEYSI 375
Query: 1213 LILYSLPQRKNQQ--NLGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEE 1268
+L L + Q NL L ++ + VP + +++D P+F + Y++++ E
Sbjct: 376 QVLKLLDREAAPQGYNLTLRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPE 435
Query: 1269 N--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
VN+PV + ++ + +N + I+ N+ F I+ G LY D E K
Sbjct: 436 TAPVNSPVIRLKVSDADQGKNALVFLEIVGGNEGG---EFYINADTGMLYTAVPLDAETK 492
Query: 1327 DTYEVIVRAERQ 1338
Y + V A Q
Sbjct: 493 AFYTLTVSAVDQ 504
Score = 58.0 bits (134), Expect = 2e-06
Identities = 52/192 (27%), Positives = 86/192 (44%), Gaps = 19/192 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ G ++++ A DLDS NGQ+ Y S + + ++ F I+ + G
Sbjct: 3433 IREDAKAGEKVVQVFANDLDSNENGQVSY-------------SIERGDRQKQFTIDSQSG 3479
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V L E + + L + A D G L++ + V + V D ND+ P+F + Y V+
Sbjct: 3480 QITVLAPLDREQIASYVLEVHAKDNGIPTLSNYVIVNIEVIDANDNPPLFAQNNYTTVVQ 3539
Query: 1056 EAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + + K TDAD N A T+ + + F + G L + +D
Sbjct: 3540 EDKPLGYAVLKFTVTDADAEPNAAPYTFDFRSGNEGDAFRLEQ-DGTLRTATKFSNRVKD 3598
Query: 1115 KYILTVVARDNG 1126
KY+L + DNG
Sbjct: 3599 KYLLHIRVFDNG 3610
Score = 57.2 bits (132), Expect = 3e-06
Identities = 58/192 (30%), Positives = 87/192 (45%), Gaps = 17/192 (8%)
Query: 940 IPENI-PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
I EN+ G I++L+A DLD + ++ Y ++ S +L++ F ++
Sbjct: 1547 ISENVVEKGEAILQLHAQDLDE--DKKLFYSLHNAQ-------SQASLQI---FHVDSLT 1594
Query: 999 GHVIVARSLPPES--EFRLNISALDGGN-LNDNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
G + + +L E+ E L + D G N + V V V D NDH P F V
Sbjct: 1595 GTITLNEALDRETIQEHILTVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISEIIQGKV 1654
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + +V A D D G+NA L+Y + + F I P G + V ELD T
Sbjct: 1655 FETSPIGTAVVQVIAIDRDRGENAQLSYSMTSGNVGNVFSIDPDLGTIRVARELDLATAS 1714
Query: 1115 KYILTVVARDNG 1126
+YIL V A D+G
Sbjct: 1715 EYILLVKATDHG 1726
Score = 57.2 bits (132), Expect = 3e-06
Identities = 79/316 (25%), Positives = 120/316 (37%), Gaps = 25/316 (7%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V D+ND+ P+F Y V V+ KV A D D G N + Y ++ +
Sbjct: 2158 VNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKKGHGE 2217
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
L F+++ TG +S+ L+ + Y L + A D G K
Sbjct: 2218 L-FKVNRKTGEISLKQNLEGHNRE-YQLMIAAYDGGISPCSVEISVNVKVIDRSMPVFDK 2275
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIP-VYKAT----IEENAPIGTTVAKVFANDTD 1205
+ D +LE + + ES + +Y T EE A T ++ D
Sbjct: 2276 QFYTDSVLESIEVHSPLALSIQAESPLNRKLIYSITKGNDFEEFALDFNTGVIYVVDELD 2335
Query: 1206 FIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+ Y L R G+ + +IL++ V D P P F Y +
Sbjct: 2336 YEQKKQ----YELTVRATDSVSGVYAEVLVSILVLDVNDCP--------PEFSQDSYNIS 2383
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRT----FVIDPRNGTLYLVR 1319
I E EL+ L ++ N K+RY I N ++ F +DP G +YL R
Sbjct: 2384 ISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGIVYLKR 2443
Query: 1320 SPDREVKDTYEVIVRA 1335
S D E D++ V A
Sbjct: 2444 SLDHETADSHHFTVVA 2459
Score = 56.4 bits (130), Expect = 6e-06
Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 231 LRYELISGNDRKLFSLDS--VNGSLFL---EKELDLDAEHNLQANTFVLQVQASQLNNPL 285
+++ + SG+ K F + V FL + +D + + + +VL+++A+ +
Sbjct: 122 IKFRIASGDKEKFFKAEERVVGDFCFLLLRTRTGHVDVLNRERKDKYVLEIKATARRHDG 181
Query: 286 KT------AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
K AQ V + +LD ND P F Y ++ E+ P S+L+V A D D G NG
Sbjct: 182 KNRVTLLEAQTTVAVTILDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNG 241
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTV 363
E Y + F++ P SG +T+
Sbjct: 242 EIYYSFAEKTEQFAVHPVSGVVTL 265
Score = 56.4 bits (130), Expect = 6e-06
Identities = 43/154 (27%), Positives = 73/154 (47%), Gaps = 13/154 (8%)
Query: 220 AIDQDLGVGATLRYEL-------ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
A D D G+ + +RY + + N LF +D G ++L++ LD + A++
Sbjct: 2399 ARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGIVYLKRSLDHET-----ADSH 2453
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V A P ++ A V + ++D+NDN P+FE YN + E G V V A+D
Sbjct: 2454 HFTVVAMDRGVPSLSSTAHVWLTVIDMNDNPPKFEQSSYNCFLSEEAERGQFVTVVSASD 2513
Query: 333 KD-QGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
D + +T + + +SID +G +T+ N
Sbjct: 2514 PDLLDDKLVYTIVGGNDQQTYSIDQSTGIITLIN 2547
Score = 52.0 bits (119), Expect = 1e-04
Identities = 87/416 (20%), Positives = 159/416 (38%), Gaps = 39/416 (9%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
F I+ + G + V + + L++ A DG + V + V + VF+K Y
Sbjct: 2018 FDIDSQSGALTVNNPENMKKSYLLHVRASDG-KYSSVAQVNIKVAKSENSGLVFQKEVYE 2076
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG-ELDR 1110
V E + ++ + ++ + + P++ F I P +G +S G DR
Sbjct: 2077 GTVVENSTKVSTVAVLNVLGSALNEHVVFS-ILNPTEM---FVIGPTSGAISTTGIRFDR 2132
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
ET DKY L +V ++ D+NDN P F + + +
Sbjct: 2133 ETIDKYEL-IVEANSQVPTQRVAHTIVNVTVLDINDNCPIF------VNLPYYAVVSVDA 2185
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
+ +M + +N + + K + + G I + + L
Sbjct: 2186 QKGDVIMKVHAIDLDSGDNGEVRYELKKGH-GELFKVNRKTGEISLKQNLEGHNREYQLM 2244
Query: 1231 SLSSTAILMVTVADVPDEVEMSDK--PVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
+ + ++ V++ D+ PVF ++Y + E++ L E N
Sbjct: 2245 IAAYDGGISPCSVEISVNVKVIDRSMPVFDKQFYTDSVLESIEVHSPLALSIQAESPLNR 2304
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
K+ Y I ND + F +D G +Y+V D E K YE+ VR
Sbjct: 2305 KLIYSITKGNDFE---EFALDFNTGVIYVVDELDYEQKKQYELTVR-------------- 2347
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
A D + G+ +V V + + DVND P+F+ + + +I A FG ++++L
Sbjct: 2348 ---ATDSVSGVYA-EVLVSILVLDVNDCPPEFSQDSYNI--SISEAALFGTELLRL 2397
Score = 50.8 bits (116), Expect = 3e-04
Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 218 IHAIDQDLGV-GATLRYELISGNDRKLFSLDSVN--GSLFLEKELDLDAEHNLQANTFVL 274
+ +D+D G G E+++G+ F + + G ++ LD E Q + L
Sbjct: 335 VRVLDRDTGPHGEIASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQG--YNL 392
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
++A P + + V + L DLNDN P F + Y++ + E P V+++ +D D
Sbjct: 393 TLRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDAD 452
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWL 361
QG+N ++ + G F I+ +G L
Sbjct: 453 QGKNALVFLEIVGGNEGGEFYINADTGML 481
Score = 50.4 bits (115), Expect = 4e-04
Identities = 77/324 (23%), Positives = 136/324 (41%), Gaps = 39/324 (12%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA---PIGPSLTIPLTVPR 136
+ V V + D ND+ P F+ V E +P G A + +IA G + + ++
Sbjct: 1628 FARVLVTVHDHNDHAPTFISEIIQGKVFETSPIGT-AVVQVIAIDRDRGENAQLSYSMTS 1686
Query: 137 G-----LTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
G +I D+ + + + + +V D G AL +S PV ++ + D
Sbjct: 1687 GNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDHGSPALSNSI-PVHVMVTMAD- 1744
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGAT--LRYELISGNDRKLFSLDS 248
+A + + SG + EI E I + + + +T L++E++SGN + F ++
Sbjct: 1745 NAPPR-----FVRSGAELAAEIYENEEIGSFVKHIEARSTSSLQFEIVSGNIGEAFFINP 1799
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
G + ++ LD + + L + A+ ++ +AQ V + +LD NDN P+F
Sbjct: 1800 STGVISTQERLDYE-----DVKFYNLSIAATSMSGA--SAQCNVIVHVLDRNDNAPQFVQ 1852
Query: 309 DFYNISIVENLPNG---FSV------LQVMATDKDQGENGEFTYQLDD--PKGAFSIDPR 357
Y + E G FS L + A D D N Y + + P+ F ID
Sbjct: 1853 AVYTGQVSEAASIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVEELPRKFFHIDSS 1912
Query: 358 SGWLTVRNQTVLDREAHSSLRMKV 381
+G +R +LD E + V
Sbjct: 1913 TG--AIRTVMLLDHETIPEFQFNV 1934
Score = 47.6 bits (108), Expect = 0.003
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 3/95 (3%)
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMA 330
+ L V+A+ + A V + +LD+NDN P F + +Y + V+ G +++V A
Sbjct: 2138 YELIVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYAVVSVD-AQKGDVIMKVHA 2196
Query: 331 TDKDQGENGEFTYQLDDPKG-AFSIDPRSGWLTVR 364
D D G+NGE Y+L G F ++ ++G ++++
Sbjct: 2197 IDLDSGDNGEVRYELKKGHGELFKVNRKTGEISLK 2231
Score = 46.8 bits (106), Expect = 0.005
Identities = 78/312 (25%), Positives = 123/312 (39%), Gaps = 45/312 (14%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + L PLF + E+ P+ +I+K++A D D G NG+I Y F
Sbjct: 199 LDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSF----------- 247
Query: 982 SADALEVKRYFVINERHGHVIVARSL--PPESEFRLNISALDGGNL------NDNISVRV 1033
E F ++ G V + R L + L + A D G L N + +
Sbjct: 248 ----AEKTEQFAVHPVSGVVTLTRPLRYVERPLYELTVQARDRGALYRMTPRASNARLTI 303
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQY-TRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
V+ VN H P +E + T ++ +D G+ A+L I D D
Sbjct: 304 HVRQVNLHAPEISVRHLPEILEHSNADTYAIVRVLDRDTGPHGEIASLE--IVAGDPDGH 361
Query: 1093 FEISPL--TGVLSVN--GELDRETEDK-YILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
F + PL G S+ LDRE + Y LT+ A D G D+NDN
Sbjct: 362 FRVRPLPTPGEYSIQVLKLLDREAAPQGYNLTLRAVDRG-TPPRFSYKSVPVHLADLNDN 420
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI 1207
+P F E+ + K PE +++ V+ + V A +NA + + +I
Sbjct: 421 APIFST--EIYDVKVPETAPVNS----PVIRLKVSDADQGKNALVFLEIVGGNEGGEFYI 474
Query: 1208 GNGNGLILYSLP 1219
G++ ++P
Sbjct: 475 NADTGMLYTAVP 486
Score = 44.4 bits (100), Expect = 0.024
Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG P S++ +L V+V DV D +K + R E + + +L E
Sbjct: 875 DLGKPQKSASRMLAVSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGE-- 932
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y ++ + +D R +D G L + DRE + +YE+ +RA + +
Sbjct: 933 -NAQVAYSLVTDT-SDFR----VDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDK- 985
Query: 1346 HMIYPVAEDVLEGMTKYDVKVV-VRIKDVNDNSPKF 1380
E + Y +V V + DVNDN+PKF
Sbjct: 986 ------GEPDFDNPALYSEALVRVSVDDVNDNAPKF 1015
Score = 43.2 bits (97), Expect = 0.056
Identities = 38/179 (21%), Positives = 81/179 (45%), Gaps = 14/179 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HAID D G +RYEL G+ +LF ++ G + L++ L+ HN + Q+
Sbjct: 2194 VHAIDLDSGDNGEVRYELKKGHG-ELFKVNRKTGEISLKQNLE---GHNRE-----YQLM 2244
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + + + + + ++ ++P F+ FY S++E++ + + +
Sbjct: 2245 IAAYDGGISPCSVEISVNVKVIDRSMPVFDKQFYTDSVLESIEVHSPLALSIQAESPLNR 2304
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
++ + F++D +G + V ++ LD E + V A + SV G +A+
Sbjct: 2305 KLIYSITKGNDFEEFALDFNTGVIYVVDE--LDYEQKKQYELTVRATD---SVSGVYAE 2358
Score = 43.2 bits (97), Expect = 0.056
Identities = 21/52 (40%), Positives = 28/52 (53%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+T ATD DIGIN IRY+ L+ F I P SG V + L R+ ++
Sbjct: 3234 VTKVHATDDDIGINRKIRYEFLDSANDHFVISPDSGIVTLAKPLDRETKAMY 3285
>UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69;
Euteleostomi|Rep: Protocadherin-15 precursor - Homo
sapiens (Human)
Length = 1955
Score = 139 bits (337), Expect = 5e-31
Identities = 129/461 (27%), Positives = 212/461 (45%), Gaps = 33/461 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + ++DANDN P F P Y+ + ++ + G + ++ AVD D G NG + Y++
Sbjct: 493 VIVNIQVMDANDNTPTF-PEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEIL-- 549
Query: 503 SNLTITSPFKINPNTGTVSVAES-PILEGR-HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F IN TG +++A ++ GR +AL V+A+D A P+ERR S+ V IEV
Sbjct: 550 --VGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADN-APPAERRNSICTVYIEVL 606
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ P P M Y + + +G + ++ D E + ++Y + +G + V F
Sbjct: 607 PPNNQSPPRFPQLM---YSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRV-F 661
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+ E +G++T+ L R + Y A + + + V DVND V
Sbjct: 662 NLSETTGILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVF--DP 719
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ P V E A A +GQ+ T+ + G V + + N ++ I +G+I+T
Sbjct: 720 YLPRNLSVVEEEANAFVGQVKATDPDA---GINGQVHYSLGNFNNL---FRITSNGSIYT 773
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
L+RE RD Y + V+A + V + I + D +DN PVF ++TY + EN
Sbjct: 774 AVKLNREVRDYYELVVVAT-DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENL 832
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE---- 856
GT I I+A D D G N + E K F + TG + + SLD E
Sbjct: 833 PAGTTILQ---IEAKDVDLGANVSYRIR-SPEVKHFFALHPFTGELSLL-RSLDYEAFPD 887
Query: 857 KKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEFNQ 895
++ + A D G A + +++ D ND P F++
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSK 928
Score = 96.7 bits (230), Expect = 4e-18
Identities = 124/475 (26%), Positives = 206/475 (43%), Gaps = 55/475 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + + + +LD +DN+PVF S Y ++ N GT I +++A D DLG N V Y
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNST-YTVLVEENLPAGTTILQIEAKDVDLGAN--VSY--- 854
Query: 501 RTSNLTITSPFKINPNTGTVSVAES------PILEGRHALFVEASDQPANPSERRYSLAV 554
R + + F ++P TG +S+ S P E VEA D +A
Sbjct: 855 RIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP---GIAT 911
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSY-- 608
VT+ V K P F Y+ V + GT + + DA + V Y
Sbjct: 912 VTVIV----KDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRV 967
Query: 609 -DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
D+ Y + F VEE SG + +L+ ++ VA + + + ++ATV ++
Sbjct: 968 DDVQFPYPASI-FEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPV-MSSSATVKIL 1025
Query: 668 DVNDER--GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
++ + P + + + N S +Y +GN ++D
Sbjct: 1026 VLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAINQSIVYSIVSGN-------EED 1078
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF------NKGVISGAGIYQVTIYIED 779
I G I+ PLD E R Y + V A+ N V S + +V I I+D
Sbjct: 1079 TFGINNIT--GVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQD 1136
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKE 835
EN++PPVF+ Y G + E++++ T + +KATD D G ++ Y L EGKE
Sbjct: 1137 ENNHPPVFQKKFYIGGVSEDARMFTSVLR---VKATDKDTGNYSVMAYRLIIPPIKEGKE 1193
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT--GGLSSEAELIIMIGDEND 888
F V+ TG++K ++ +K ++A D GLS +A++++ + ++ D
Sbjct: 1194 GFVVETYTGLIK-TAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 87.4 bits (207), Expect = 3e-15
Identities = 121/480 (25%), Positives = 206/480 (42%), Gaps = 57/480 (11%)
Query: 441 SFVNVEVTLLDANDNNPVF---VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
S V + + D NDN PVF +P NL ++NA +G+VKA DPD G NG V Y
Sbjct: 699 STATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANA----FVGQVKATDPDAGINGQVHY 754
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
L +NL F+I N G++ A E R + L V A+D +P +LA+
Sbjct: 755 SLGNFNNL-----FRITSN-GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIK 808
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+++ + P F + Y V N+ GT++ QI D +VSY + E
Sbjct: 809 VLDIDDNS-------PVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSY-RIRSPE 860
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL-----SIVTNATVHVVDVN 670
FA+ +G ++++ L P + L E ++ + TV V D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ--DVTD 728
D V K + ++ + G I ++ + + G VR+ + + Q
Sbjct: 921 DYPPVFSKRIYKGMV--APDAVKGTPITTVYAED-ADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 729 DIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKG--VISGAGIYQVTIYIEDENDNPP 785
+ ED G + T+ L+ E ++++ V+A F+ G V+S + ++ + E P
Sbjct: 978 IFEVEEDSGRVITRVNLNEEPTTIFKLVVVA-FDDGEPVMSSSATVKILVLHPGE---IP 1033
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
F Y S++ T+ M +I A N +Y++ G ++ F ++ TG
Sbjct: 1034 RFTQEEYRP--PPVSELATKGTMVGVISAA----AINQSIVYSIVSGNEEDTFGINNITG 1087
Query: 845 VVKFIGDSLDREKKIMYKLSLVARD---------TGGLSSEAELIIMIGDENDNKPEFNQ 895
V+ ++ LD E + Y L + A S+ A++ I I DEN++ P F +
Sbjct: 1088 VI-YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQK 1146
Score = 84.2 bits (199), Expect = 2e-14
Identities = 112/453 (24%), Positives = 179/453 (39%), Gaps = 68/453 (15%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G ++I+L A+D D G NG+I YE + + F+IN+ G + +A
Sbjct: 525 GDSVIQLTAVDADEGSNGEITYEI--------------LVGAQGDFIINKTTGLITIAPG 570
Query: 1007 LPP--ESEFRLNISALDGG----NLNDNISVRVFVKDVNDHFPV-FKKTWYNFNVEEAQY 1059
+ + L + A D N +V + V N+ P F + Y+ + EA
Sbjct: 571 VEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMR 630
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
VL + ATD + ++TY I+ D F +S TG+L++ LDRE+ D+YIL
Sbjct: 631 VGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILI 687
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
+ A D DVNDN+P FD L +E +N +
Sbjct: 688 ITASDG--RPDGTSTATVNIVVTDVNDNAP---VFDPYLPRNLSVVEEEAN------AFV 736
Query: 1180 PVYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILYSLPQRKNQQNL----------G 1228
KAT + +A I V N + F NG I ++ + ++
Sbjct: 737 GQVKAT-DPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
+ ST L + V D+ D + PVF + Y + +EEN+ A ++ + +
Sbjct: 796 VHPRHSTLTLAIKVLDIDD-----NSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGA 850
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
+ Y I +++ F + P G L L+RS D E E +
Sbjct: 851 NVSYRI---RSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASI-------------TF 894
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
A D+ M V V +KD+ND P F+
Sbjct: 895 LVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Score = 72.9 bits (171), Expect = 6e-11
Identities = 115/502 (22%), Positives = 208/502 (41%), Gaps = 65/502 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI-----GKVKAVDPDLGQNGMVLYDL 499
V + + D NDN+P F + Y ++ VGT I G A D D G NG + Y +
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYA-TVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 500 QR-----TSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSL 552
Q TSN T P + TG + + + E R+ + ++A+D+ N +ERR +
Sbjct: 192 QYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 553 AVVTIEVTRGTKGNK--------PDIPDFMGAPYEFWVGS-------NVGIGT----SVG 593
+T++V G P+ D Y+ + N I T ++
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 594 QIR-VNDAFEQNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVAL 650
Q R + ++ + Y +L G E P F + R+ +++++ ++R +D A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 651 QENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH-TNMSSI 708
Q+N + L + ++D N++ ++ I ++ GA I + T+ I
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYI--LESAPVGATISDSLNLTSPLRI 426
Query: 709 YG-----NGTGNVRF-LIANQQDVTDDIAIAEDGT---IFTQKPLDREKRDVYRMTVIAE 759
T + L N D T + + G + +P+DRE++ Y ++ A
Sbjct: 427 VALDKDIEDTKDPELHLFLN--DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA- 483
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
F+ GV + V I + D NDN P F +Y+ ++ + + G + + A DADE
Sbjct: 484 FD-GVQESEPVI-VNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ---LTAVDADE 538
Query: 820 GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAEL 879
G+N Y + + F +++ TG++ I ++ Y L++ A D +
Sbjct: 539 GSNGEITYEILVGAQGDFIINKTTGLIT-IAPGVEMIVGRTYALTVQAADNAPPAERRNS 597
Query: 880 IIMIGDE-----NDNKPEFNQI 896
I + E N + P F Q+
Sbjct: 598 ICTVYIEVLPPNNQSPPRFPQL 619
Score = 67.7 bits (158), Expect = 2e-09
Identities = 38/124 (30%), Positives = 66/124 (53%), Gaps = 2/124 (1%)
Query: 227 VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN--LQANTFVLQVQASQLNNP 284
+ ++ Y ++SGN+ F ++++ G +++ LD + + L+ L+V + L P
Sbjct: 1063 INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVP 1122
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
K+ A+V IE+ D N++ P F+ FY + E+ SVL+V ATDKD G Y+
Sbjct: 1123 SKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYR 1182
Query: 345 LDDP 348
L P
Sbjct: 1183 LIIP 1186
Score = 66.9 bits (156), Expect = 4e-09
Identities = 50/159 (31%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G ++ Y + +G+ +++F+L G L L K LD ++ + ++L + AS P T
Sbjct: 645 GDSITYAIENGDPQRVFNLSETTGILTLGKALDRES-----TDRYILIITASD-GRPDGT 698
Query: 288 AQARVEIELLDLNDNLPEFEVDF-YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
+ A V I + D+NDN P F+ N+S+VE N F V QV ATD D G NG+ Y L
Sbjct: 699 STATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLG 757
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ F I ++ L+RE + V A +
Sbjct: 758 NFNNLFRITSNG---SIYTAVKLNREVRDYYELVVVATD 793
Score = 66.9 bits (156), Expect = 4e-09
Identities = 48/160 (30%), Positives = 80/160 (50%), Gaps = 10/160 (6%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F + A D D G+ + Y L GN LF + S NGS++ +L+ + + +
Sbjct: 735 FVGQVKATDPDAGINGQVHYSL--GNFNNLFRITS-NGSIYTAVKLNREVR-----DYYE 786
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V A+ + + + I++LD++DN P F Y + + ENLP G ++LQ+ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREA 373
D G N + + + K F++ P +G L++ LD EA
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEA 884
Score = 66.1 bits (154), Expect = 7e-09
Identities = 119/479 (24%), Positives = 201/479 (41%), Gaps = 50/479 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+ S V + +L N+ +P P +Y + +VG V+ ++A D + +
Sbjct: 593 ERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSIT 649
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAV 554
Y ++ + F ++ TG +++ ++ E R+ L + ASD + + S A
Sbjct: 650 YAIENGDPQRV---FNLSETTGILTLGKALDRESTDRYILIITASDGRPDGT----STAT 702
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLH 612
V I VT N P ++ P V VGQ++ D A V Y L
Sbjct: 703 VNIVVT-DVNDNAPVFDPYL--PRNLSVVEEEA-NAFVGQVKATDPDAGINGQVHYSL-- 756
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVND 671
G + F + + T V L+R R Y+ VA + T + V+D++D
Sbjct: 757 GNFNNL-FRITSNGSIYTAVK-LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDD 814
Query: 672 ERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
V ++ + V+EN AG I QI ++ NV + I + + V
Sbjct: 815 NSPVFTNSTYTVL---VEENLPAGTTILQIEAKDVDL-----GANVSYRIRSPE-VKHFF 865
Query: 731 AIAE-DGTIFTQKPLDREK---RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
A+ G + + LD E ++ ++ F+ GI VT+ ++D ND PPV
Sbjct: 866 ALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPV 925
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNA-LFMYTL----FGEGKEMFDVD 840
F Y+G + ++ GT I + A DAD G A Y + F +F+V+
Sbjct: 926 FSKRIYKGMVAPDAVKGTPI---TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVE 982
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
E++G V +L+ E ++KL +VA D G +SS A + I++ + P F Q E
Sbjct: 983 EDSGRV-ITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEE 1039
Score = 62.1 bits (144), Expect = 1e-07
Identities = 85/331 (25%), Positives = 131/331 (39%), Gaps = 29/331 (8%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
+V + + DVNDN P+F PY + AF+ + P I V L F
Sbjct: 702 TVNIVVTDVNDNAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNF 759
Query: 142 KDI-RAFDRDKPNTP---NSDV--HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
++ R T N +V +Y +V DG A+ H + L KVLD D
Sbjct: 760 NNLFRITSNGSIYTAVKLNREVRDYYELVVVATDG--AVHPRHSTLTLAIKVLDIDDNSP 817
Query: 196 EFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
F V++ IL I A D DLG A + Y + S + F+L G
Sbjct: 818 VFTNSTYTVLVEENLPAGTTIL---QIEAKDVDLG--ANVSYRIRSPEVKHFFALHPFTG 872
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
L L + LD +A + +A+ L V+A + + A V + + D+ND P F Y
Sbjct: 873 ELSLLRSLDYEAFPDQEASITFL-VEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIY 931
Query: 312 NISIVENLPNGFSVLQVMATDKDQG--ENGEFTYQLDD-----PKGAFSIDPRSGWLTVR 364
+ + G + V A D D Y++DD P F ++ SG + R
Sbjct: 932 KGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITR 991
Query: 365 NQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
L+ E + ++ V A + V+ + A
Sbjct: 992 --VNLNEEPTTIFKLVVVAFDDGEPVMSSSA 1020
Score = 60.1 bits (139), Expect = 5e-07
Identities = 67/219 (30%), Positives = 98/219 (44%), Gaps = 37/219 (16%)
Query: 929 LDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD+D P+F L+ EN+P GTTI+++ A D+D G N + Y S
Sbjct: 810 LDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSP-------- 859
Query: 982 SADALEVKRYFVINERHGHVIVARSLP----PESEFRLN--ISALD-GGNLNDNI-SVRV 1033
EVK +F ++ G + + RSL P+ E + + A D G + I +V V
Sbjct: 860 -----EVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTV 914
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLP 1092
VKD+ND+ PVF K Y V + V A DAD G A+ + + D P
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRY-RVDDVQFP 973
Query: 1093 -----FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
FE+ +G + L+ E + L VVA D+G
Sbjct: 974 YPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDG 1012
Score = 59.7 bits (138), Expect = 6e-07
Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 6/150 (4%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A+D+D+ L + +F++ + +L +D E + T+
Sbjct: 423 PLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDRE---EQQTYTF 479
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A + ++ V I+++D NDN P F Y++ + ++ G SV+Q+ A D D
Sbjct: 480 SITA--FDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 537
Query: 335 QGENGEFTYQ-LDDPKGAFSIDPRSGWLTV 363
+G NGE TY+ L +G F I+ +G +T+
Sbjct: 538 EGSNGEITYEILVGAQGDFIINKTTGLITI 567
Score = 51.2 bits (117), Expect = 2e-04
Identities = 44/177 (24%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G + YE++ G F ++ G + + +++ + T+ L VQA+
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD-FIINKTTGLITIAPGVEM-----IVGRTYALTVQAA 586
Query: 280 QLNNPLKTAQA--RVEIELLDLNDNLP-EFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
P + + V IE+L N+ P F Y++ I E + G +L + ATD+ +G
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDR-EG 645
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
++ + + DP+ F++ +G LT+ LDRE+ + + A + P T
Sbjct: 646 DSITYAIENGDPQRVFNLSETTGILTLGK--ALDRESTDRYILIITASDGRPDGTST 700
Score = 50.4 bits (115), Expect = 4e-04
Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 1/116 (0%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
+ + +I+A DG ++ + V + V D ND+ P F + Y+ V + ++ A
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
DAD G N +TY I F I+ TG++++ ++ Y LTV A DN
Sbjct: 534 VDADEGSNGEITYEILVG-AQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADN 588
Score = 46.4 bits (105), Expect = 0.006
Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 992 FVINERHGHVIVARSL--PPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F + E G VI +L P + F+L + A D G ++ + +V++ V + P F +
Sbjct: 979 FEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQ 1037
Query: 1048 TWYNFN-VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
Y V E ++G + A N ++ Y I + + F I+ +TGV+ VNG
Sbjct: 1038 EEYRPPPVSELATKGTMVGVISAAAI----NQSIVYSIVSGNEEDTFGINNITGVIYVNG 1093
Query: 1107 ELDRETEDKYILTVVA 1122
LD ET Y+L V A
Sbjct: 1094 PLDYETRTSYVLRVQA 1109
Score = 44.8 bits (101), Expect = 0.018
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Query: 740 TQKPLDREK-RDVYRMTVIAE-FNKGVISGAGIY-QVTIYIEDENDNPPVFEHATYEGFI 796
T + LDR+ +++ + V + NK V G IY +V I + D NDN P F+H +Y +
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKV--GTIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 797 MENSKIGTEI--KMDNIIKATDADEGTNALFMYTL 829
E + +GT I ATD D+G N Y +
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Score = 44.0 bits (99), Expect = 0.032
Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL-----GKVDATDADFGQNANLTYFIQ 1085
VR+ V+D ND+ P FK Y V E + G ATD D G N + Y IQ
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 1086 --PSD--TDLPFEIS-PLTGVLSVNGELDRETEDKYILTVVARD 1124
P D ++ FEI LTG + + L+ E + +Y + + A D
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQAND 236
Score = 41.1 bits (92), Expect = 0.23
Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 13/114 (11%)
Query: 246 LDSVNGSLFLEKE-LDLDAEHNLQANTFVLQVQASQLNNPLKTA-QARVEIELLDLNDNL 303
+D V LFL LD + + ++ V+QVQ +N + T V I + D NDN
Sbjct: 87 MDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQC--INKKVGTIIYHEVRIVVRDRNDNS 144
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVM-----ATDKDQGENGEFTYQL----DDP 348
P F+ + Y ++ E P G ++ ATD D G NG+ Y + DDP
Sbjct: 145 PTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDP 198
Score = 39.1 bits (87), Expect = 0.92
Identities = 17/38 (44%), Positives = 21/38 (55%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF 117
Y V + + D NDN P F Y+ TV+ELTP G F
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIF 167
Score = 38.3 bits (85), Expect = 1.6
Identities = 62/270 (22%), Positives = 111/270 (41%), Gaps = 34/270 (12%)
Query: 145 RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMAS 204
RA + ++ T + + ++ G+D G L P + L Y A E + +
Sbjct: 237 RAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELR-----T 291
Query: 205 GKRIHKEILFPEPIHAIDQDLGVGAT-----LRYELISGNDR---KLFSLDSVNGSLFLE 256
+ ++ I+ P PI AIDQD + + Y ++ G + F + L L
Sbjct: 292 PEELNPIIVTP-PIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLL 350
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV 316
+ ++ D F L ++A Q N A A + IE+LD N+ P F + Y I+
Sbjct: 351 EPVNRDFHQK-----FDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 317 ENLPNGFSV---------LQVMATDKD--QGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
E+ P G ++ L+++A DKD ++ E L+D F++ +
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 366 QTVLDREAHSSLRMKVYA----KETNPSVV 391
+DRE + + A +E+ P +V
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEPVIV 495
>UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin -
Aedes aegypti (Yellowfever mosquito)
Length = 2413
Score = 139 bits (336), Expect = 6e-31
Identities = 125/511 (24%), Positives = 229/511 (44%), Gaps = 43/511 (8%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+ D SF V++T+L AN +NP F Y+ + N G ++ VKA D D G
Sbjct: 230 NVSVTDGVYTSFTRVKITILPANLHNPTF-EHLFYDVKVNENQLAGRLVTTVKAQDKDFG 288
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
+ G + Y + I F I+ + G + V + + L+ + P +
Sbjct: 289 EFGRLTYFIISDE---IQEYFSIDKDKGEI-VTKKKLDREERKLY----EVPIMAMDSGG 340
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSY 608
T+ V G + + P P F+ Y+ + N+ T+ +++ D+ + + V Y
Sbjct: 341 RAGFTTVRVNVGDENDNP--PVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKY 398
Query: 609 DLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+ G+ F ++E +G I + R+ ++ F + + S+ T+ + +
Sbjct: 399 SIFDSQNSGIKELFGIDENTGGIYLRKSAVRWENQLFQF-FIRANDGGVPSLYTDVPIDI 457
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
++ A +P +F KE + + T ++ + +G ++ I + +
Sbjct: 458 Y--------IMSSAENPPVFEKKEKLLFLSESSLPGTVITRLKLSGNVTAKYRILSDELE 509
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+I G + K LDRE +DV+ + ++AE + A + VT++++DENDN P+
Sbjct: 510 EPQFSINNVGELRLAKTLDRELKDVHLIAILAETDSSPPLTA-VTDVTLHVQDENDNTPM 568
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENT 843
FE Y + EN + G+ I + A D+D G+N Y+L G+ +FD+D T
Sbjct: 569 FESNPYSFSLAENIEKGSSIMK---LTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYT 625
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSK 901
G + + LD+EK+ YK ++A D G S+ +II + D ND P F + +
Sbjct: 626 GWITTL-VPLDKEKREDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKAS 684
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVD 932
V E L GT +++++ +K DVD
Sbjct: 685 V---SEDALPGT---VVLQIETTDK---DVD 706
Score = 135 bits (327), Expect = 8e-30
Identities = 227/967 (23%), Positives = 383/967 (39%), Gaps = 138/967 (14%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V V+++D NDN P F + Y + +A G + V A DPD + + Y
Sbjct: 136 LSSTAHVWVSVMDMNDNPPKFEQPS-YTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYT 194
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + + L + INP +G +++ +H + S + S V I
Sbjct: 195 IAQGNEL---QTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDGVYT----SFTRVKIT 247
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEE 616
+ N P F Y+ V N G V ++ D E ++Y ++ E
Sbjct: 248 ILPANLHN----PTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISD-EI 302
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F++++ G I L R R +Y+ +A+ T V+V D ND V
Sbjct: 303 QEYFSIDKDKGEIVTKKKLDREERKLYEVPIMAMDSGGRAGFTT-VRVNVGDENDNPPVF 361
Query: 677 LKGAHSPIIF-HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDDIAIA 733
L + +I ++ N+ F N V++ I + Q+ + + I
Sbjct: 362 LLREYKALIQGNLTTNTT------FFRVKAVDSDDNQNAVVKYSIFDSQNSGIKELFGID 415
Query: 734 ED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E+ G I+ +K R + +++ + A + GV S + IYI +NPPVFE
Sbjct: 416 ENTGGIYLRKSAVRWENQLFQFFIRAN-DGGVPSLYTDVPIDIYIMSSAENPPVFEKKEK 474
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIG 850
F+ E+S GT I T N Y + + E F ++ N G ++ +
Sbjct: 475 LLFLSESSLPGTVI--------TRLKLSGNVTAKYRILSDELEEPQFSIN-NVGELR-LA 524
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
+LDRE K ++ ++++A E D+ P + + V +H + +
Sbjct: 525 KTLDRELKDVHLIAILA------------------ETDSSPPLTAVTD---VTLHVQDEN 563
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+ T F E P + F + ENI G++I+KL A D DSG NG IRY
Sbjct: 564 DNTPMF---ESNPYS------------FSLAENIEKGSSIMKLTARDSDSGSNGDIRYSL 608
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDN 1028
++EV D + + F I+ G + L E +++ + A D G +
Sbjct: 609 STEV--------GDIVNI---FDIDAYTGWITTLVPLDKEKREDYKFQVIATDNGQPKHS 657
Query: 1029 ISVRVFV--KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
V + KD ND P FK++ Y +V E V+ +++ TD D N+ Y+I
Sbjct: 658 TRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVLQIETTDKDVDLKTNIEYYIIS 717
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
D F+I +G + V LDRE+ +Y L V+ D D ND
Sbjct: 718 GDPLSQFQIKN-SGEVFVVKTLDRESISQYELGVIVTDG----KFTSTANISVTVLDAND 772
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N P Y L++++ E H V+ I N+ + + A D +
Sbjct: 773 NPP--YC----LKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLTGNGAEDFNL 826
Query: 1207 IGNGNGLILYSLPQRKNQQNLGL---------PSLSSTAILMVTVADVPDEVEMSDKPVF 1257
+ L R+ Q L P ++ + +T+ D+ D + P F
Sbjct: 827 DKDSGQLKTARQLDRETQSKFHLVAHVQDRDHPGWECSSQIEITITDLND-----NPPDF 881
Query: 1258 ISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
Y + + E+ + ++ T+ N K++Y ++ R F I P +G +
Sbjct: 882 SMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFID----SYRDHFKIAPDSGIV 937
Query: 1316 YLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVND 1375
L + DREVK Y + VRA Q L + + +VV ++D+ND
Sbjct: 938 TLAKPLDREVKAVYNLTVRATDQG-KPSLSNSAF----------------LVVNVQDIND 980
Query: 1376 NSPKFTN 1382
N P+FT+
Sbjct: 981 NPPEFTS 987
Score = 122 bits (294), Expect = 8e-26
Identities = 126/491 (25%), Positives = 212/491 (43%), Gaps = 34/491 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + S N+ VT+LDAND NP + Y + GT + +++A D D N +
Sbjct: 754 DGKFTSTANISVTVLDAND-NPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRL 812
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ L T N F ++ ++G + A E + + A Q + S
Sbjct: 813 RFYL--TGN--GAEDFNLDKDSGQLKTARQLDRETQSKFHLVAHVQDRDHPGWECS---S 865
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHG 613
IE+T + P PDF PY + + +GT V +I DA + Y +
Sbjct: 866 QIEITITDLNDNP--PDFSMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFIDS 923
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVNDE 672
Y + F + SG++T+ L R + +Y+ A Q +LS V+V D+ND
Sbjct: 924 YRD--HFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQGKPSLSNSAFLVVNVQDINDN 981
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + ++ +S G + ++ T+ + + + I +
Sbjct: 982 PPEFTSKHYFASV--LENSSIGTEVLRVLATSKDT---GINAEITYSIIGGNEHRKFAMH 1036
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G ++ +D E+ Y +T+ A + G + + V I + D NDNPP F +Y
Sbjct: 1037 NKTGVLYLADVVDYERAKDYFLTIQA-VDGGTPPLSNLATVNISVADCNDNPPQFTANSY 1095
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGD 851
I E+++ G ++ I+A D D G N+ Y + G+ FD++E+TG + G
Sbjct: 1096 TATIREDAQKGDKMLQ---IRANDMDSGENSRVSYRIERGDRMGQFDIEEDTGYISVAG- 1151
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
+LDRE Y L + ARD G LS+ + I I D NDN P F N+ + +E K
Sbjct: 1152 TLDRESISSYVLEVQARDHGSPSLSTYVLVNIEISDANDNPPLFT---SNNYTAVVQEDK 1208
Query: 910 LNGTAGFTIIE 920
GFT+++
Sbjct: 1209 ---QIGFTLLK 1216
Score = 119 bits (286), Expect = 7e-25
Identities = 133/483 (27%), Positives = 218/483 (45%), Gaps = 41/483 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V + D ND P + + Y ++ A+ GT I KV+A D D G N +V Y LQ
Sbjct: 33 VPVSVLVQDVNDCPPE-IEQDSYNITVSERAQFGTAILKVQAKDNDTGINQVVTYALQTD 91
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVT 560
S T + F ++P G + + +S E H V ASD+ PS S A V + V
Sbjct: 92 SKNT-SEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKGV-PS--LSSTAHVWVSVM 147
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGV 618
+ P P F Y + + G V + +D + + ++Y + G E
Sbjct: 148 --DMNDNP--PKFEQPSYTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYTIAQG-NELQ 202
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
+ + SG+IT+V ++ + V++ + S T + ++ N L
Sbjct: 203 TYDINPVSGIITLV-NMQNFAEKHVTILNVSVTDGVYTSF-TRVKITILPAN-----LHN 255
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIAED-G 736
+ + VK N A G++ T + G G + + I + ++ + +I +D G
Sbjct: 256 PTFEHLFYDVKVNENQLA-GRLVTTVKAQDKDFGEFGRLTYFIIS-DEIQEYFSIDKDKG 313
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T+K LDRE+R +Y + ++A + G AG V + + DENDNPPVF Y+ I
Sbjct: 314 EIVTKKKLDREERKLYEVPIMAMDSGG---RAGFTTVRVNVGDENDNPPVFLLREYKALI 370
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGDS 852
N T +KA D+D+ NA+ Y++F KE+F +DENTG + ++ S
Sbjct: 371 QGNLTTNTTFFR---VKAVDSDDNQNAVVKYSIFDSQNSGIKELFGIDENTGGI-YLRKS 426
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
R + +++ + A D G L ++ + I I +N P F E+ K+ E+ L
Sbjct: 427 AVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPPVF---EKKEKLLFLSESSL 483
Query: 911 NGT 913
GT
Sbjct: 484 PGT 486
Score = 110 bits (265), Expect = 2e-22
Identities = 123/464 (26%), Positives = 203/464 (43%), Gaps = 30/464 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + L D ND P F S+ Y+ S+ +A GTV+ +++ D D+ + Y +
Sbjct: 662 VIIRLKDYNDCPPTFKESH-YKASVSEDALPGTVVLQIETTDKDVDLKTNIEYYIISGDP 720
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
L S F+I N+G V V ++ E + + ++ +++ + I VT
Sbjct: 721 L---SQFQIK-NSGEVFVVKTLDRES-----ISQYELGVIVTDGKFT-STANISVTVLDA 770
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
+ P P + Y + V GT V QI+ ND E + F +++
Sbjct: 771 NDNP--PYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLTGNGAEDFNLDK 828
Query: 625 RSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
SG + L R + + A V +++ + + + D+ND +S
Sbjct: 829 DSGQLKTARQLDRETQSKFHLVAHVQDRDHPGWECSSQIEITITDLNDNPPDFSMNPYSV 888
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT-QK 742
+ ++ G + +I H + I N F+ D IA D I T K
Sbjct: 889 TL--PEDAEVGTLVTKI-HATDADIGINRKIKYSFI----DSYRDHFKIAPDSGIVTLAK 941
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + VY +TV A ++G S + + + ++D NDNPP F Y ++ENS I
Sbjct: 942 PLDREVKAVYNLTVRAT-DQGKPSLSNSAFLVVNVQDINDNPPEFTSKHYFASVLENSSI 1000
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMY 861
GTE+ + AT D G NA Y++ G + F + TGV+ ++ D +D E+ Y
Sbjct: 1001 GTEVLR---VLATSKDTGINAEITYSIIGGNEHRKFAMHNKTGVL-YLADVVDYERAKDY 1056
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
L++ A D G LS+ A + I + D NDN P+F + +R
Sbjct: 1057 FLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTANSYTATIR 1100
Score = 105 bits (252), Expect = 9e-21
Identities = 126/466 (27%), Positives = 204/466 (43%), Gaps = 41/466 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+E+T+ D NDN P F N Y ++ +A+VGT++ K+ A D D+G N + Y +
Sbjct: 867 IEITITDLNDNPPDF-SMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFIDSYR 925
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
FKI P++G V++A+ E + + L V A+DQ PS + VV ++
Sbjct: 926 ----DHFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQ-GKPSLSNSAFLVVNVQDIN- 979
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPF 620
+ P P+F Y V N IGT V ++ D +++Y ++ G E F
Sbjct: 980 ---DNP--PEFTSKHYFASVLENSSIGTEVLRVLATSKDTGINAEITYSIIGGNEHR-KF 1033
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLK 678
A+ ++GV+ + D + Y R F + + LS + + V D ND
Sbjct: 1034 AMHNKTGVLYLADVVD-YERAKDYFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTA 1092
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GT 737
+++ I ++ G + QI +M S V + I + D I ED G
Sbjct: 1093 NSYTATIR--EDAQKGDKMLQIRANDMDS---GENSRVSYRI-ERGDRMGQFDIEEDTGY 1146
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I LDRE Y + V A + G S + V I I D NDNPP+F Y +
Sbjct: 1147 ISVAGTLDRESISSYVLEVQAR-DHGSPSLSTYVLVNIEISDANDNPPLFTSNNYTAVVQ 1205
Query: 798 ENSKIG-TEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTGVVKFIGDSL 853
E+ +IG T +K + TDAD NA YT G F ++++ G+++
Sbjct: 1206 EDKQIGFTLLKFE----VTDADAAPNAA-PYTFDVRSGNDGGAFRIEQD-GILR-TASRF 1258
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
+ + K Y L + D G L S+ + I + +E+ P ++
Sbjct: 1259 NSKIKDTYLLGIRVFDNGSPPLYSDTWVSIKVIEESQYPPVITPLD 1304
Score = 103 bits (246), Expect = 5e-20
Identities = 90/325 (27%), Positives = 144/325 (44%), Gaps = 26/325 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPRG--- 137
+ + I D+NDN P F PY VT+ E G A IG + I +
Sbjct: 867 IEITITDLNDNPPDFSMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFIDSYRD 926
Query: 138 -LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
I D KP Y++ V D G +L +S L+ V D +
Sbjct: 927 HFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQGKPSLSNS---AFLVVNVQDINDNPP 983
Query: 196 EFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
EF + I E+L + A +D G+ A + Y +I GN+ + F++ + G
Sbjct: 984 EFTSKHYFASVLENSSIGTEVL---RVLATSKDTGINAEITYSIIGGNEHRKFAMHNKTG 1040
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
L+L +D + +A + L +QA P + A V I + D NDN P+F + Y
Sbjct: 1041 VLYLADVVDYE-----RAKDYFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTANSY 1095
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVL 369
+I E+ G +LQ+ A D D GEN +Y+++ D G F I+ +G+++V L
Sbjct: 1096 TATIREDAQKGDKMLQIRANDMDSGENSRVSYRIERGDRMGQFDIEEDTGYISVAG--TL 1153
Query: 370 DREAHSSLRMKVYAKETNPSVVGTF 394
DRE+ SS ++V A++ + T+
Sbjct: 1154 DRESISSYVLEVQARDHGSPSLSTY 1178
Score = 89.0 bits (211), Expect = 9e-16
Identities = 68/215 (31%), Positives = 105/215 (48%), Gaps = 20/215 (9%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN IGT ++++ A D+G+N +I Y S R F ++ + G +
Sbjct: 996 ENSSIGTEVLRVLATSKDTGINAEITY-------------SIIGGNEHRKFAMHNKTGVL 1042
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EE 1056
+A + E ++ L I A+DGG L++ +V + V D ND+ P F Y + E+
Sbjct: 1043 YLADVVDYERAKDYFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTANSYTATIRED 1102
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
AQ ++L ++ A D D G+N+ ++Y I+ D F+I TG +SV G LDRE+ Y
Sbjct: 1103 AQKGDKML-QIRANDMDSGENSRVSYRIERGDRMGQFDIEEDTGYISVAGTLDRESISSY 1161
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+L V ARD+G D NDN P F
Sbjct: 1162 VLEVQARDHG-SPSLSTYVLVNIEISDANDNPPLF 1195
Score = 86.2 bits (204), Expect = 6e-15
Identities = 98/405 (24%), Positives = 172/405 (42%), Gaps = 33/405 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ +GT + K++A D D G+N +I+Y F + Y K++ D+ G
Sbjct: 890 LPEDAEVGTLVTKIHATDADIGINRKIKYSF-IDSYRDHFKIAPDS-------------G 935
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V +A+ L E + + L + A D G +L+++ + V V+D+ND+ P F Y +V
Sbjct: 936 IVTLAKPLDREVKAVYNLTVRATDQGKPSLSNSAFLVVNVQDINDNPPEFTSKHYFASVL 995
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V AT D G NA +TY I + F + TGVL + +D E
Sbjct: 996 ENSSIGTEVLRVLATSKDTGINAEITYSIIGGNEHRKFAMHNKTGVLYLADVVDYERAKD 1055
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADELSNHNF 1173
Y LT+ A D G D NDN P+F A + + + D++
Sbjct: 1056 YFLTIQAVDGG-TPPLSNLATVNISVADCNDNPPQFTANSYTATIREDAQKGDKML--QI 1112
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKV-FANDTDFIGNGNGLILYSLPQ---RKNQQNLGL 1229
+ M + + G + + DT +I L S+ ++ G
Sbjct: 1113 RANDMDSGENSRVSYRIERGDRMGQFDIEEDTGYISVAGTLDRESISSYVLEVQARDHGS 1172
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK 1289
PSLS+ ++ + ++D D + P+F S Y ++E+ L+ +T+
Sbjct: 1173 PSLSTYVLVNIEISDAND-----NPPLFTSNNYTAVVQEDKQIGFTLLKFEVTDADAAPN 1227
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
Y + + F I+ ++G L + ++KDTY + +R
Sbjct: 1228 AAPYTFDVRSGNDGGAFRIE-QDGILRTASRFNSKIKDTYLLGIR 1271
Score = 83.0 bits (196), Expect = 6e-14
Identities = 86/331 (25%), Positives = 147/331 (44%), Gaps = 19/331 (5%)
Query: 1013 FRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDAT 1070
+ L I A D ++ + V V V+DVND P ++ YN V E AQ+ +L KV A
Sbjct: 16 YELLIRATDSVSGVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQFGTAIL-KVQAK 74
Query: 1071 DADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D D G N +TY +Q +T F + P GV+ + LD ET + TV+A D G
Sbjct: 75 DNDTGINQVVTYALQTDSKNTSEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKG-V 133
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
D+NDN PKF E + ++ + F V ++ +
Sbjct: 134 PSLSSTAHVWVSVMDMNDNPPKF----EQPSYTCVLSEHATRGQF--VTVVSASDPDYID 187
Query: 1189 NAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE 1248
+ + T+A+ T I +G+I Q ++++ + ++S T + + V
Sbjct: 188 HDRLTYTIAQGNELQTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDGVYTSFTRVKIT 247
Query: 1249 VEMSD--KPVFISRYYELEIEENVNAP--VELVSLNLTEHYENFKMRYYILNENDTDIRR 1304
+ ++ P F +Y++++ EN A V V + E ++ Y+I+++ +I+
Sbjct: 248 ILPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISD---EIQE 304
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
F ID G + + DRE + YEV + A
Sbjct: 305 YFSIDKDKGEIVTKKKLDREERKLYEVPIMA 335
Score = 78.6 bits (185), Expect = 1e-12
Identities = 104/410 (25%), Positives = 168/410 (40%), Gaps = 46/410 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ GT ++++ D D L I Y YI +S D L F I + G
Sbjct: 685 VSEDALPGTVVLQIETTDKDVDLKTNIEY------YI----ISGDPLS---QFQI-KNSG 730
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V V ++L ES ++ L + DG ++ V V D ND+ P K Y + E
Sbjct: 731 EVFVVKTLDRESISQYELGVIVTDG-KFTSTANISVTVLDANDNPPYCLKYRYREQLSEG 789
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + ++ A D D N+ L +++ + + F + +G L +LDRET+ K+
Sbjct: 790 VHPGTYVLQIQANDIDEPANSRLRFYLTGNGAE-DFNLDKDSGQLKTARQLDRETQSKFH 848
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L +D D+NDN P F + PE E+ V
Sbjct: 849 LVAHVQDRDHPGWECSSQIEITIT-DLNDNPPDFSMNPYSVTL--PEDAEVGT----LVT 901
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL------- 1227
I A I N I + + D I +G++ + P + K NL
Sbjct: 902 KIHATDADIGINRKIKYSFIDSY-RDHFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQ 960
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G PSLS++A L+V V D+ D + P F S++Y + EN + E++ + T
Sbjct: 961 GKPSLSNSAFLVVNVQDIND-----NPPEFTSKHYFASVLENSSIGTEVLRVLATSKDTG 1015
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y I+ N+ R F + + G LYL D E Y + ++A
Sbjct: 1016 INAEITYSIIGGNE---HRKFAMHNKTGVLYLADVVDYERAKDYFLTIQA 1062
Score = 77.8 bits (183), Expect = 2e-12
Identities = 51/166 (30%), Positives = 83/166 (50%), Gaps = 13/166 (7%)
Query: 225 LGVGATLRYELISGN-DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
L T +Y ++S + FS+++V G L L K LD + + + ++ + A ++
Sbjct: 493 LSGNVTAKYRILSDELEEPQFSINNV-GELRLAKTLDRELK-----DVHLIAILAETDSS 546
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
P TA V + + D NDN P FE + Y+ S+ EN+ G S++++ A D D G NG+ Y
Sbjct: 547 PPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTARDSDSGSNGDIRY 606
Query: 344 QLDDPKG----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
L G F ID +GW+T LD+E + +V A +
Sbjct: 607 SLSTEVGDIVNIFDIDAYTGWIT--TLVPLDKEKREDYKFQVIATD 650
Score = 76.2 bits (179), Expect = 7e-12
Identities = 93/427 (21%), Positives = 172/427 (40%), Gaps = 36/427 (8%)
Query: 921 VKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
V+ N +++Q + E GT I+K+ A D D+G+N + Y
Sbjct: 39 VQDVNDCPPEIEQDSYNITVSERAQFGTAILKVQAKDNDTGINQVVTYA----------- 87
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVK 1036
L D+ YF ++ G + + +SL E S + A D G +L+ V V V
Sbjct: 88 LQTDSKNTSEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKGVPSLSSTAHVWVSVM 147
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
D+ND+ P F++ Y + E + + V A+D D+ + LTY I + ++I+
Sbjct: 148 DMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYTIAQGNELQTYDIN 207
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
P++G++++ + + IL V D N ++P F
Sbjct: 208 PVSGIITLVNMQNFAEKHVTILNVSVTDG----VYTSFTRVKITILPANLHNPTF----- 258
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGNGL 1213
+H D N N + ++ KA ++ G + +++ I G
Sbjct: 259 ----EHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISDEIQEYFSIDKDKGE 314
Query: 1214 ILYSLPQRKNQQNL---GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
I+ + ++ L + ++ S T V E + PVF+ R Y+ I+ N+
Sbjct: 315 IVTKKKLDREERKLYEVPIMAMDSGGRAGFTTVRVNVGDENDNPPVFLLREYKALIQGNL 374
Query: 1271 --NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
N V ++ +N ++Y I + ++ I+ F ID G +YL +S R
Sbjct: 375 TTNTTFFRVKAVDSDDNQNAVVKYSIFDSQNSGIKELFGIDENTGGIYLRKSAVRWENQL 434
Query: 1329 YEVIVRA 1335
++ +RA
Sbjct: 435 FQFFIRA 441
Score = 74.1 bits (174), Expect = 3e-11
Identities = 52/169 (30%), Positives = 87/169 (51%), Gaps = 9/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D + LR+ L +GN + F+LD +G L ++LD + + + F L
Sbjct: 799 IQANDIDEPANSRLRFYL-TGNGAEDFNLDKDSGQLKTARQLDRETQ-----SKFHLVAH 852
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++P +++EI + DLNDN P+F ++ Y++++ E+ G V ++ ATD D G
Sbjct: 853 VQDRDHPGWECSSQIEITITDLNDNPPDFSMNPYSVTLPEDAEVGTLVTKIHATDADIGI 912
Query: 338 NGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + Y +D + F I P SG +T+ LDRE + + V A +
Sbjct: 913 NRKIKYSFIDSYRDHFKIAPDSGIVTLAKP--LDREVKAVYNLTVRATD 959
Score = 66.1 bits (154), Expect = 7e-09
Identities = 83/332 (25%), Positives = 140/332 (42%), Gaps = 24/332 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L+R ++ +SA + V+V ++DVND P Y++TV E G I +
Sbjct: 19 LIRATDSVSGVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQFGTA--ILKVQAKDN 76
Query: 127 SLTIPLTVPRGL-TIFKDIRAFDRDKPNTPNSDVHYSIVSGN-DDGHFALESSHKPVLLL 184
I V L T K+ + P + S+ HF + +S K V L
Sbjct: 77 DTGINQVVTYALQTDSKNTSEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKGVPSL 136
Query: 185 RK-------VLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELI 236
V+D + +F+ H F + A D D L Y +
Sbjct: 137 SSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYTIA 196
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
GN+ + + ++ V+G + L ++ ++ + + +L V + + + T+ RV+I +
Sbjct: 197 QGNELQTYDINPVSGIITL-----VNMQNFAEKHVTILNVSVT---DGVYTSFTRVKITI 248
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
L N + P FE FY++ + EN G V V A DKD GE G TY + D+ + FSI
Sbjct: 249 LPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISDEIQEYFSI 308
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
D G + + + LDRE + + A ++
Sbjct: 309 DKDKGEIVTKKK--LDREERKLYEVPIMAMDS 338
Score = 66.1 bits (154), Expect = 7e-09
Identities = 70/322 (21%), Positives = 124/322 (38%), Gaps = 28/322 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
++A VT++++D NDN P+F PY ++ E G +
Sbjct: 549 LTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTARDSDSGSNGDIRYSL 608
Query: 137 GLTIFKDIRAFDRDK-----------PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ + FD D D + +++ D+G + ++ L+
Sbjct: 609 STEVGDIVNIFDIDAYTGWITTLVPLDKEKREDYKFQVIA-TDNGQPKHSTRTTVIIRLK 667
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
D KE S + ++ I D+D+ + + Y +ISG+ F
Sbjct: 668 DYNDCPPTFKESHYKASVSEDALPGTVVLQ--IETTDKDVDLKTNIEYYIISGDPLSQFQ 725
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+ + +G +F+ K LD ++ + V + T+ A + + +LD NDN P
Sbjct: 726 IKN-SGEVFVVKTLDRESISQYELGVIVTDGKF--------TSTANISVTVLDANDNPPY 776
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTV 363
Y + E + G VLQ+ A D D+ N + L GA F++D SG L
Sbjct: 777 CLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLTG-NGAEDFNLDKDSGQLKT 835
Query: 364 RNQTVLDREAHSSLRMKVYAKE 385
Q LDRE S + + ++
Sbjct: 836 ARQ--LDRETQSKFHLVAHVQD 855
Score = 59.7 bits (138), Expect = 6e-07
Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 19/192 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ G ++++ A D+DSG N ++ Y D + F I E G
Sbjct: 1099 IREDAQKGDKMLQIRANDMDSGENSRVSYRIER----------GDRMG---QFDIEEDTG 1145
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ VA +L ES + L + A D G+ L+ + V + + D ND+ P+F Y V+
Sbjct: 1146 YISVAGTLDRESISSYVLEVQARDHGSPSLSTYVLVNIEISDANDNPPLFTSNNYTAVVQ 1205
Query: 1056 EAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + L K + TDAD N A T+ ++ + F I G+L + + +D
Sbjct: 1206 EDKQIGFTLLKFEVTDADAAPNAAPYTFDVRSGNDGGAFRIEQ-DGILRTASRFNSKIKD 1264
Query: 1115 KYILTVVARDNG 1126
Y+L + DNG
Sbjct: 1265 TYLLGIRVFDNG 1276
Score = 59.3 bits (137), Expect = 8e-07
Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 11/210 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G + + Y + G+ F ++ G + + LD ++ +++VL+VQ
Sbjct: 1112 IRANDMDSGENSRVSYRIERGDRMGQFDIEEDTGYISVAGTLDRES-----ISSYVLEVQ 1166
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + V IE+ D NDN P F + Y + E+ GF++L+ TD D
Sbjct: 1167 ARDHGSPSLSTYVLVNIEISDANDNPPLFTSNNYTAVVQEDKQIGFTLLKFEVTDADAAP 1226
Query: 338 NG---EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
N F + + GAF I+ + G L ++ + L ++V+ + P T+
Sbjct: 1227 NAAPYTFDVRSGNDGGAFRIE-QDGILRTASRFNSKIKDTYLLGIRVFDNGSPPLYSDTW 1285
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPDK 424
+ I + + P+ T PL+ + F D+
Sbjct: 1286 VSIKVIEESQYPPVIT--PLDVSINSFQDE 1313
Score = 56.0 bits (129), Expect = 7e-06
Identities = 45/147 (30%), Positives = 73/147 (49%), Gaps = 13/147 (8%)
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
++++ ELD + Q ++ L ++A+ + + +A+ V + + D+ND PE E D Y
Sbjct: 1 AIYVVDELDYE-----QRQSYELLIRATDSVSGV-SAEVPVSVLVQDVNDCPPEIEQDSY 54
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGA---FSIDPRSGWLTVRNQT 367
NI++ E G ++L+V A D D G N TY L D K F +DP G + ++
Sbjct: 55 NITVSERAQFGTAILKVQAKDNDTGINQVVTYALQTDSKNTSEYFHMDPTDGVIYLKKS- 113
Query: 368 VLDREAHSSLRMKVYAKETN-PSVVGT 393
LD E S V A + PS+ T
Sbjct: 114 -LDHETLSHHHFTVIASDKGVPSLSST 139
Score = 55.2 bits (127), Expect = 1e-05
Identities = 43/156 (27%), Positives = 68/156 (43%), Gaps = 12/156 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G L Y +IS ++ FS+D G + +K+LD + E L +V
Sbjct: 280 VKAQDKDFGEFGRLTYFIISDEIQEYFSIDKDKGEIVTKKKLDRE-ERKLY------EVP 332
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+++ + V + + D NDN P F + Y I NL + +V A D D +
Sbjct: 333 IMAMDSGGRAGFTTVRVNVGDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQ 392
Query: 338 NGEFTYQLDDP-----KGAFSIDPRSGWLTVRNQTV 368
N Y + D K F ID +G + +R V
Sbjct: 393 NAVVKYSIFDSQNSGIKELFGIDENTGGIYLRKSAV 428
Score = 40.7 bits (91), Expect = 0.30
Identities = 20/52 (38%), Positives = 28/52 (53%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+T ATD+DIGIN I+Y ++ F I P SG V + L R+ V+
Sbjct: 900 VTKIHATDADIGINRKIKYSFIDSYRDHFKIAPDSGIVTLAKPLDREVKAVY 951
Score = 36.7 bits (81), Expect = 4.9
Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 848 FIGDSLDREKKIMYKLSLVARDT-GGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ D LD E++ Y+L + A D+ G+S+E + +++ D ND PE Q N V
Sbjct: 3 YVVDELDYEQRQSYELLIRATDSVSGVSAEVPVSVLVQDVNDCPPEIEQDSYNITV 58
>UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A
CG6977-PA; n=2; Endopterygota|Rep: PREDICTED: similar to
Cad87A CG6977-PA - Apis mellifera
Length = 1907
Score = 138 bits (334), Expect = 1e-30
Identities = 250/1027 (24%), Positives = 404/1027 (39%), Gaps = 136/1027 (13%)
Query: 345 LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSL-RMKVYAKETNPSVVGTFADSQRIAKW 403
LD G D G L + TV R+ + R +Y TNP D +
Sbjct: 243 LDSLTGVVREDDPIGTLVM---TVKARDGDRGMPRKMIYELVTNPFDYFLLDDETGELRT 299
Query: 404 RRQPLETNAPLEKTTYVFPDKVGTKT--ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVP 461
+ PL A L+ +T V KV + + + D +S VT+ D ND P F
Sbjct: 300 AK-PLNREA-LKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFNR 357
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAV--DPDLGQNGMVLYDLQRTSN--LTITSPFKINPNT 517
Y + N GT + + DPD+G N + L+ ++ TI +
Sbjct: 358 RE-YNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDITDGAFTIEPTMATGSTS 416
Query: 518 GTVSVAESPI-----LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
+ VA + + + + V A + +P + S A VT+ +T + P
Sbjct: 417 VNIRVANGSLDYENPNQRKFIILVVAEEVHTDP--KLSSTATVTVSITDANDNS----PT 470
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSYDLLHGYEEGVPFAVEERSGV 628
F Y V GT V I D F ++Y LL + F+V+ +SG+
Sbjct: 471 FSNPTYTAVVLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLG--QGAQHFSVDRKSGI 528
Query: 629 ITVVDDLSRYNRPMYDFEA---------VALQENANLSIVTNATVHVVDVNDERGVLLKG 679
ITV + P D+E + + + + + D ND L+
Sbjct: 529 ITVAPCANPGTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQD 588
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSS--IYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ +I E Q + +S Y G+ L A QD T +I I G
Sbjct: 589 KYRAVIDEGAEKFEPDLKVQARDKDKTSKITYAIVGGDELDLFAIDQD-TGEITIKNKG- 646
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
P+D + ++ + + G+ + I +TI D N+N PVF H Y +
Sbjct: 647 -----PVDLTNSTHDWIALVIQASDGIFVDSAIVNITI--RDVNNNAPVFPHELYTASLP 699
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
E S IGT ++ + ATDAD G NA +Y + + F ++E TG+V + LD +
Sbjct: 700 EISPIGTVVEE---VTATDADTGINAELVYRIQKGAFDDFTINETTGIVT-VFRKLDYDN 755
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
K Y + ++A D G L+ L+I + + ND P F E + + +T + GT
Sbjct: 756 KNTYHVEVIAFDKGTPSLTGTTTLMINVENSNDKAPYFT--PETQRAEVTEDTPI-GTV- 811
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
FT + K + + +V+ L F I E I A+D NGQ
Sbjct: 812 FTTL--KATDPDSTNVEALN--FAISEPI---------TAID----RNGQ---------Q 845
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI-----S 1030
+ SK D +F ++ G V V RSL + ++I+ + + +
Sbjct: 846 VNDSKSFKD------FFAVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAPTLQQGRGT 899
Query: 1031 VRVFVKDVNDHFPVFKKTW------YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+ V + DVN P F K W Y ++E Q T ++G A DAD N I
Sbjct: 900 LVVTIIDVNHMAPEFLKPWTRENPRYLIEMQEEQPTGAIVGAFTAVDAD--SNIAGYAII 957
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
PS F I +TG++ + +D E + TVVA D+G ++
Sbjct: 958 PPSPY---FNIDNVTGIVRTSQVIDYEETKQLEFTVVAYDSG-VPQLSATTKVIVTVINI 1013
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG-TTVAKVFAND 1203
ND PKF EL E H + V KAT + P G + + + +
Sbjct: 1014 NDQDPKFE--KELYNASVKENSPPGTH-------VIVVKATDGDEGPFGEVSYSLIGDHA 1064
Query: 1204 TDF-IGNGNGLILY---SLPQRKNQQNLGLPSLSSTAILM-----VTVADVPDEVEMSD- 1253
DF IG+ G I ++ R+ N+ + ++S + TV V ++++D
Sbjct: 1065 ADFNIGHETGEITVGSAAVLDREITPNITITVMASDGAHINSRRSTTVPVVVKLIDVNDN 1124
Query: 1254 KPVFISRYYELEIEEN--VNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVID 1309
+P+F Y + EN VN P ++ + +H E N ++ Y I++ N+ + +F ++
Sbjct: 1125 RPIFTQHSYRASVAENLPVNPPAPILQVRAVDHDEGINGEVWYTIIHGNENE---SFSLN 1181
Query: 1310 PRNGTLY 1316
G LY
Sbjct: 1182 HETGILY 1188
Score = 100 bits (239), Expect = 4e-19
Identities = 165/706 (23%), Positives = 276/706 (39%), Gaps = 85/706 (12%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL------- 499
+ + ++ND P F P + + +GTV +KA DPD + + +
Sbjct: 781 INVENSNDKAPYFTPET-QRAEVTEDTPIGTVFTTLKATDPDSTNVEALNFAISEPITAI 839
Query: 500 -----QRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSER-RYS 551
Q + + F ++ TG VSV S + ++ V SD A ++ R +
Sbjct: 840 DRNGQQVNDSKSFKDFFAVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAPTLQQGRGT 899
Query: 552 LAVVTIEVTR-GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
L V I+V + KP + Y + G VG DA + N Y +
Sbjct: 900 LVVTIIDVNHMAPEFLKPWTRE--NPRYLIEMQEEQPTGAIVGAFTAVDA-DSNIAGYAI 956
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
+ F ++ +G++ + +F VA LS T V V+++
Sbjct: 957 I---PPSPYFNIDNVTGIVRTSQVIDYEETKQLEFTVVAYDSGVPQLSATTKVIVTVINI 1013
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND+ K ++ VKENS + + G V + + +
Sbjct: 1014 NDQDPKFEKELYNA---SVKENSPPGT--HVIVVKATDGDEGPFGEVSYSLIGDHAADFN 1068
Query: 730 IAIAEDG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI-YQVTIYIEDENDNPPV 786
I E G T+ + LDRE +TV+A + S V + + D NDN P+
Sbjct: 1069 IG-HETGEITVGSAAVLDREITPNITITVMASDGAHINSRRSTTVPVVVKLIDVNDNRPI 1127
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
F +Y + EN + + + +A D DEG N YT+ G E F
Sbjct: 1128 FTQHSYRASVAENLPVNPPAPILQV-RAVDHDEGINGEVWYTIIHGNENESF-------- 1178
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
SL+ E I+Y + + G E E D N P ++ + +V
Sbjct: 1179 ------SLNHETGILYPGAALLGRAGSYRIEVEA----RDGAGNGPHSDKCYVDIRV--- 1225
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI-GTTIIKLNALDLDSGLNG 964
T +N + K +F L + +PEN + I+ + A+D D G NG
Sbjct: 1226 --TPVN----------QHKPQFVLP-ELTNATVEVPENTGVLNYLILTVKAIDRDPGENG 1272
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDG 1022
++ Y K+ ++ F I++ G + L E S+F L + A D
Sbjct: 1273 RVSYHL---------KVGNRNIQETEEFSIDQETGELRSKIILDREVKSKFELVLVAADH 1323
Query: 1023 GNLNDNISVRVF---VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
G ++R+ + D ND+ P F Y+F + E + +GKV A D D G++A
Sbjct: 1324 GTPTAYETLRLLTVQLVDTNDNTPQFYDE-YHFQISENRPKDYFVGKVIAEDKDEGRHAK 1382
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ Y+I+ + + F I G + N DRET DKY+L+++A ++
Sbjct: 1383 VYYYIEAGNENYAFYIDKSDGSIYTNKSFDRETRDKYVLSILASND 1428
Score = 86.6 bits (205), Expect = 5e-15
Identities = 111/412 (26%), Positives = 169/412 (41%), Gaps = 46/412 (11%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG--TVIGKVKAVDPDLGQNGMVLYDLQ 500
V V V L+D NDN P+F + Y S+ N V I +V+AVD D G NG V Y +
Sbjct: 1112 VPVVVKLIDVNDNRPIFTQHS-YRASVAENLPVNPPAPILQVRAVDHDEGINGEVWYTII 1170
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPI-LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ F +N TG + + + G + + VEA D N V I V
Sbjct: 1171 HGNE---NESFSLNHETGILYPGAALLGRAGSYRIEVEARDGAGNGPHS--DKCYVDIRV 1225
Query: 560 TRGTKGNKPD--IPDFMGAPYEFWVGSNVGI-GTSVGQIRV--NDAFEQNDVSYDLLHG- 613
T + +KP +P+ A E V N G+ + ++ D E VSY L G
Sbjct: 1226 TPVNQ-HKPQFVLPELTNATVE--VPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGN 1282
Query: 614 --YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDV 669
+E F++++ +G + L R + ++ VA + T TV +VD
Sbjct: 1283 RNIQETEEFSIDQETGELRSKIILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDT 1342
Query: 670 NDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND H F + EN +G++ + G ++ A ++
Sbjct: 1343 NDNTPQFYDEYH----FQISENRPKDYFVGKVIAEDKDE--GRHAKVYYYIEAGNENYAF 1396
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGA------------GIYQVTI 775
I DG+I+T K DRE RD Y ++++A + + IS A G VTI
Sbjct: 1397 YID-KSDGSIYTNKSFDRETRDKYVLSILASNDPDIYISPADAGRPLMHNTDHGYVNVTI 1455
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
I DENDN P+FE Y + + + + + A+D D G N Y
Sbjct: 1456 IILDENDNSPIFERNDYYAGVNSMANVNDFVTK---VTASDLDVGDNGTLHY 1504
Score = 77.8 bits (183), Expect = 2e-12
Identities = 47/143 (32%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F++D+V G + + +D + L+ V A P +A +V + ++++ND
Sbjct: 963 FNIDNVTGIVRTSQVIDYEETKQLE-----FTVVAYDSGVPQLSATTKVIVTVININDQD 1017
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLT 362
P+FE + YN S+ EN P G V+ V ATD D+G GE +Y L D F+I +G +T
Sbjct: 1018 PKFEKELYNASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLIGDHAADFNIGHETGEIT 1077
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
V + VLDRE ++ + V A +
Sbjct: 1078 VGSAAVLDREITPNITITVMASD 1100
Score = 70.5 bits (165), Expect = 3e-10
Identities = 86/300 (28%), Positives = 123/300 (41%), Gaps = 36/300 (12%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL---TIPLTV---PRGL 138
V + D NDN P FL+ PY +E P G + I I P L TI LT P+ L
Sbjct: 117 VIVLDDNDNPPRFLNVPYEAVAEEDLPVGS-TILSGIKVIDPDLLGDTIDLTCVPQPQFL 175
Query: 139 TIFKDIRAFDRDK-------------PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ D +K P Y ++ DG L + V +
Sbjct: 176 DACEKFGIVDVEKRQNSYTGALVLRQPLDYRERPFYQLLLRASDG---LNNETTGVEI-- 230
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
KV D EF + + + A D D G+ + YEL++ N F
Sbjct: 231 KVADIQNSPPEFLDSLTGVVREDDPIGTLVMTVKARDGDRGMPRKMIYELVT-NPFDYFL 289
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL------NNPLKTAQARVEIELLDL 299
LD G L K L+ +A + L+V+A +L N+ L + A + + D+
Sbjct: 290 LDDETGELRTAKPLNREALKD-STGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDV 348
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSV--LQVMATDKDQGENGEFTYQLDD-PKGAFSIDP 356
ND P F YNI I EN+PNG + L + D D G N F+ +L+D GAF+I+P
Sbjct: 349 NDEPPTFNRREYNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDITDGAFTIEP 408
Score = 69.7 bits (163), Expect = 6e-10
Identities = 93/370 (25%), Positives = 159/370 (42%), Gaps = 44/370 (11%)
Query: 47 DSPQNVVKFRLGCDFDEGDDL----VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
D+ +V+ D++E L V +G+ Q+SA V V + ++ND P F Y
Sbjct: 966 DNVTGIVRTSQVIDYEETKQLEFTVVAYDSGVPQLSATTKVIVTVININDQDPKFEKELY 1025
Query: 103 HVTVDELTPTGEKAFIFLIA-----PIGP-SLTIPLTVPRGLTIFKDI------RAFDRD 150
+ +V E +P G + P G S ++ I + A D
Sbjct: 1026 NASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLIGDHAADFNIGHETGEITVGSAAVLD 1085
Query: 151 KPNTPNSDVHYSIVSGNDDGHF-ALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIH 209
+ TPN + V +D H + S+ PV++ K++D + F + +
Sbjct: 1086 REITPNITI---TVMASDGAHINSRRSTTVPVVV--KLIDVNDNRPIFTQHSYRASVAEN 1140
Query: 210 KEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
+ P PI A+D D G+ + Y +I GN+ + FSL+ G L+ L L
Sbjct: 1141 LPVNPPAPILQVRAVDHDEGINGEVWYTIIHGNENESFSLNHETGILYPGAAL-LG---- 1195
Query: 267 LQANTFVLQVQASQ-LNNPLKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENL-PN 321
+A ++ ++V+A N + + V+I + +N + P+F E+ + + EN
Sbjct: 1196 -RAGSYRIEVEARDGAGNGPHSDKCYVDIRVTPVNQHKPQFVLPELTNATVEVPENTGVL 1254
Query: 322 GFSVLQVMATDKDQGENGEFTYQLD------DPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
+ +L V A D+D GENG +Y L FSID +G L R++ +LDRE S
Sbjct: 1255 NYLILTVKAIDRDPGENGRVSYHLKVGNRNIQETEEFSIDQETGEL--RSKIILDREVKS 1312
Query: 376 SLRMKVYAKE 385
+ + A +
Sbjct: 1313 KFELVLVAAD 1322
Score = 67.7 bits (158), Expect = 2e-09
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 16/189 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGN----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ AID+D G + Y L GN + + FS+D G L ++ LD E + F
Sbjct: 1261 VKAIDRDPGENGRVSYHLKVGNRNIQETEEFSIDQETGEL--RSKIILDREVK---SKFE 1315
Query: 274 LQVQASQLNNPLKTAQARV-EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L + A+ P R+ ++L+D NDN P+F D Y+ I EN P + V +V+A D
Sbjct: 1316 LVLVAADHGTPTAYETLRLLTVQLVDTNDNTPQF-YDEYHFQISENRPKDYFVGKVIAED 1374
Query: 333 KDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
KD+G + + Y ++ + AF ID G ++ DRE + + A +P +
Sbjct: 1375 KDEGRHAKVYYYIEAGNENYAFYIDKSDG--SIYTNKSFDRETRDKYVLSILA-SNDPDI 1431
Query: 391 VGTFADSQR 399
+ AD+ R
Sbjct: 1432 YISPADAGR 1440
Score = 67.3 bits (157), Expect = 3e-09
Identities = 49/166 (29%), Positives = 85/166 (51%), Gaps = 10/166 (6%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y ++ G++ LF++D G + ++ + +D ++ + L +QAS + + A
Sbjct: 618 ITYAIVGGDELDLFAIDQDTGEITIKNKGPVDLTNSTH-DWIALVIQAS---DGIFVDSA 673
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
V I + D+N+N P F + Y S+ E P G V +V ATD D G N E Y++ KG
Sbjct: 674 IVNITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQ--KG 731
Query: 351 A---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
A F+I+ +G +TV + D + + + + K T PS+ GT
Sbjct: 732 AFDDFTINETTGIVTVFRKLDYDNKNTYHVEVIAFDKGT-PSLTGT 776
Score = 67.3 bits (157), Expect = 3e-09
Identities = 62/227 (27%), Positives = 100/227 (44%), Gaps = 27/227 (11%)
Query: 940 IPENIPIG--TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ EN+P+ I+++ A+D D G+NG++ Y + + E F +N
Sbjct: 1137 VAENLPVNPPAPILQVRAVDHDEGINGEVWYTI----------IHGNENES---FSLNHE 1183
Query: 998 HGHVIVARSLPPES-EFRLNISALDG---GNLNDNISVRVFVKDVNDHFPVFK-KTWYNF 1052
G + +L + +R+ + A DG G +D V + V VN H P F N
Sbjct: 1184 TGILYPGAALLGRAGSYRIEVEARDGAGNGPHSDKCYVDIRVTPVNQHKPQFVLPELTNA 1243
Query: 1053 NVEEAQYT---RRVLGKVDATDADFGQNANLTYFIQPSDTDLP----FEISPLTGVLSVN 1105
VE + T ++ V A D D G+N ++Y ++ + ++ F I TG L
Sbjct: 1244 TVEVPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGNRNIQETEEFSIDQETGELRSK 1303
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
LDRE + K+ L +VA D+G D NDN+P+FY
Sbjct: 1304 IILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDTNDNTPQFY 1350
Score = 64.9 bits (151), Expect = 2e-08
Identities = 118/488 (24%), Positives = 198/488 (40%), Gaps = 66/488 (13%)
Query: 447 VTLLDAND-NNPVFVPSNLYE--FSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+ ++ AN+ N P + N Y ++ + KVGT + +K DP+ V Y +Q
Sbjct: 11 IEMIRANNVNEPPILEPNGYPAGLTLSESTKVGTEVFVLKGHDPE---GSPVKYGIQ--- 64
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+T F +NP TG +++A+ E + + + P+ ++ ++ V V
Sbjct: 65 ---LTDHFVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYVIVLD 121
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSV-GQIRVNDAFEQNDV-------SYDLLHGYE 615
+ P P F+ PYE ++ +G+++ I+V D D L E
Sbjct: 122 DNDNP--PRFLNVPYEAVAEEDLPVGSTILSGIKVIDPDLLGDTIDLTCVPQPQFLDACE 179
Query: 616 EGVPFAVEER----SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
+ VE+R +G + + L RP Y + + N + T + V D+ +
Sbjct: 180 KFGIVDVEKRQNSYTGALVLRQPLDYRERPFYQL-LLRASDGLN-NETTGVEIKVADIQN 237
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQD--VT 727
L + V+E+ IG + T + G + L+ N D +
Sbjct: 238 SPPEFL----DSLTGVVREDD---PIGTLVMTVKARDGDRGMPRKMIYELVTNPFDYFLL 290
Query: 728 DDIAIAEDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISG--------AGIYQVTIYIE 778
DD E G + T KPL+RE +D + + + +I G + T+ I+
Sbjct: 291 DD----ETGELRTAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIK 346
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEI-KMDNIIKATDADEGTNALFMYTLFGEGKEMF 837
D ND PP F Y I EN GT + +D +K D D G N++F L F
Sbjct: 347 DVNDEPPTFNRREYNIEIPENVPNGTPLPHLDMTVK--DPDVGLNSVFSLRLEDITDGAF 404
Query: 838 DVDE-----NTGV-VKFIGDSLDREKKIMYK--LSLVARDT---GGLSSEAELIIMIGDE 886
++ +T V ++ SLD E K + +VA + LSS A + + I D
Sbjct: 405 TIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDA 464
Query: 887 NDNKPEFN 894
NDN P F+
Sbjct: 465 NDNSPTFS 472
Score = 63.7 bits (148), Expect = 4e-08
Identities = 119/467 (25%), Positives = 182/467 (38%), Gaps = 54/467 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT +I + A D D G G++ Y + +AD F I G
Sbjct: 1029 VKENSPPGTHVIVVKATDGDEGPFGEVSYSLIGDH-------AAD-------FNIGHETG 1074
Query: 1000 HVIVARSLPPESEFRLNIS----ALDGGNLNDNIS--VRVFVK--DVNDHFPVFKKTWYN 1051
+ V + + E NI+ A DG ++N S V V VK DVND+ P+F + Y
Sbjct: 1075 EITVGSAAVLDREITPNITITVMASDGAHINSRRSTTVPVVVKLIDVNDNRPIFTQHSYR 1134
Query: 1052 FNVEEAQYTR--RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+V E + +V A D D G N + Y I + + F ++ TG+L L
Sbjct: 1135 ASVAENLPVNPPAPILQVRAVDHDEGINGEVWYTIIHGNENESFSLNHETGILYPGAAL- 1193
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE--WKHPEADE 1167
Y + V ARD VN + P+F EL + PE
Sbjct: 1194 LGRAGSYRIEVEARDGAGNGPHSDKCYVDIRVTPVNQHKPQF-VLPELTNATVEVPENTG 1252
Query: 1168 LSNHNFESVMMI---PVYKATIEENAPIGT---TVAKVFANDTDFIGNGNGLILYSLPQR 1221
+ N+ +V I P + + +G + F+ D + + +IL +
Sbjct: 1253 VLNYLILTVKAIDRDPGENGRVSYHLKVGNRNIQETEEFSIDQETGELRSKIILDREVKS 1312
Query: 1222 KNQQNL-----GLPSLSST-AILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAP 1273
K + L G P+ T +L V + D D + P F Y+ +I EN +
Sbjct: 1313 KFELVLVAADHGTPTAYETLRLLTVQLVDTND-----NTPQFYDEYH-FQISENRPKDYF 1366
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
V V + + K+ YYI N+ F ID +G++Y +S DRE +D Y + +
Sbjct: 1367 VGKVIAEDKDEGRHAKVYYYIEAGNE---NYAFYIDKSDGSIYTNKSFDRETRDKYVLSI 1423
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
A P ++ V V + I D NDNSP F
Sbjct: 1424 LASNDPDIYISP---ADAGRPLMHNTDHGYVNVTIIILDENDNSPIF 1467
Score = 58.4 bits (135), Expect = 1e-06
Identities = 94/378 (24%), Positives = 158/378 (41%), Gaps = 40/378 (10%)
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
R + +TIE+ R N+P I + G P + + +GT V ++ +D E + V Y
Sbjct: 3 RITAQPLTIEMIRANNVNEPPILEPNGYPAGLTLSESTKVGTEVFVLKGHDP-EGSPVKY 61
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE---NANLSIV-TNATV 664
G + F V R+GVIT+ L R F E +IV +A V
Sbjct: 62 ----GIQLTDHFVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYV 117
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-----NVRFL 719
V+D ND L + + ++ G+ I + G+ +FL
Sbjct: 118 IVLDDNDNPPRFLNVPYEAVA--EEDLPVGSTILSGIKVIDPDLLGDTIDLTCVPQPQFL 175
Query: 720 IANQQDVTDDIAIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
A ++ D+ ++ G + ++PLD +R Y++ + A + G+ + V I
Sbjct: 176 DACEKFGIVDVEKRQNSYTGALVLRQPLDYRERPFYQLLLRA--SDGLNNETT--GVEIK 231
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D ++PP F + G + E+ IGT + +KA D D G +Y L +
Sbjct: 232 VADIQNSPPEFLDSL-TGVVREDDPIGTLVMT---VKARDGDRGMPRKMIYELVTNPFDY 287
Query: 837 FDVDENTGVVKFIGDSLDRE----KKIMYKLSLVARDT-GGLS-------SEAELIIMIG 884
F +D+ TG ++ L+RE + L + AR+ G+ S AE + I
Sbjct: 288 FLLDDETGELR-TAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIK 346
Query: 885 DENDNKPEFNQIEENSKV 902
D ND P FN+ E N ++
Sbjct: 347 DVNDEPPTFNRREYNIEI 364
Score = 56.0 bits (129), Expect = 7e-06
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
LD E+ Q +L V +P ++ A V + + D NDN P F Y ++E P
Sbjct: 426 LDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTYTAVVLETAP 485
Query: 321 NGFSVLQVMATDKDQGENGE--FTYQLDDPKGA--FSIDPRSGWLTV 363
G V+ + A D+D G G YQL +GA FS+D +SG +TV
Sbjct: 486 PGTPVITITAKDRDSGRFGTAGIAYQLLG-QGAQHFSVDRKSGIITV 531
Score = 52.0 bits (119), Expect = 1e-04
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 23/207 (11%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRY--EFNSEVYIPPSKLSADALEVKRYFVIN 995
F I EN P + K+ A D D G + ++ Y E +E Y S ++ + F
Sbjct: 1355 FQISENRPKDYFVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGSIYTNKSFDRE 1414
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGN-LNDN-----ISVRVFVKDVNDHFPVFKKTW 1049
R +V+ S+ ++ + IS D G L N ++V + + D ND+ P+F++
Sbjct: 1415 TRDKYVL---SILASNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDNSPIFERND 1471
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-----------QPSDTDLPFE-ISP 1097
Y V + KV A+D D G N L Y++ +PS + +P I
Sbjct: 1472 YYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYVASANLYKYGSEKPSGSIVPSPFIVT 1531
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARD 1124
G L +G + +D++I+ V+A++
Sbjct: 1532 QDGKLVTSGYMAEYNQDRFIVEVIAKE 1558
Score = 52.0 bits (119), Expect = 1e-04
Identities = 43/141 (30%), Positives = 67/141 (47%), Gaps = 13/141 (9%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN-----LQ 268
F + A D+D G A + Y + +GN+ F +D +GS++ K D + L
Sbjct: 1366 FVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGSIYTNKSFDRETRDKYVLSILA 1425
Query: 269 ANTFVLQVQASQLNNPL----KTAQARVEIELLDLNDNLPEFE-VDFY-NISIVENLPNG 322
+N + + + PL V I +LD NDN P FE D+Y ++ + N+ N
Sbjct: 1426 SNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDNSPIFERNDYYAGVNSMANV-ND 1484
Query: 323 FSVLQVMATDKDQGENGEFTY 343
F V +V A+D D G+NG Y
Sbjct: 1485 F-VTKVTASDLDVGDNGTLHY 1504
Score = 49.2 bits (112), Expect = 9e-04
Identities = 59/231 (25%), Positives = 97/231 (41%), Gaps = 20/231 (8%)
Query: 218 IHAIDQDLGVGAT--LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL---QANTF 272
I A D+D G T + Y+L+ G + FS+D +G + + + L + +
Sbjct: 493 ITAKDRDSGRFGTAGIAYQLL-GQGAQHFSVDRKSGIITVAPCANPGTSPCLDYEEQTEY 551
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L +A+ + +T + I L D ND+ P F D Y I E L+V A D
Sbjct: 552 FLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQDKYRAVIDEGAEKFEPDLKVQARD 611
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD--REAHSSLRMKVYAKETNPSV 390
KD+ + D F+ID +G +T++N+ +D H + + + A +
Sbjct: 612 KDKTSKITYAIVGGDELDLFAIDQDTGEITIKNKGPVDLTNSTHDWIALVIQASD----- 666
Query: 391 VGTFADSQRIAKWRRQPLETNAPL---EKTTYVFPD--KVGTKTENIEYYD 436
G F DS I + + NAP+ E T P+ +GT E + D
Sbjct: 667 -GIFVDS-AIVNITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTATD 715
Score = 48.8 bits (111), Expect = 0.001
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+VNV + +LD NDN+P+F N Y + S A V + KV A D D+G NG + Y +
Sbjct: 1450 YVNVTIIILDENDNSPIF-ERNDYYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYV-A 1507
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
++NL +K + S+ SP + + V S A ++ R+ + V+ E
Sbjct: 1508 SANL-----YKYGSEKPSGSIVPSPFIVTQDGKLV-TSGYMAEYNQDRFIVEVIAKE 1558
Score = 47.2 bits (107), Expect = 0.003
Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 6/133 (4%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
E + A D D G+ A L Y + G F+++ G + + ++LD D + NT+ ++
Sbjct: 709 EEVTATDADTGINAELVYRIQKGAFDD-FTINETTGIVTVFRKLDYDNK-----NTYHVE 762
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A P T + I + + ND P F + + E+ P G + ATD D
Sbjct: 763 VIAFDKGTPSLTGTTTLMINVENSNDKAPYFTPETQRAEVTEDTPIGTVFTTLKATDPDS 822
Query: 336 GENGEFTYQLDDP 348
+ + +P
Sbjct: 823 TNVEALNFAISEP 835
Score = 39.5 bits (88), Expect = 0.69
Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 8/99 (8%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKG 350
VEI++ D+ ++ PEF +D + E+ P G V+ V A D D+G + Y+L +P
Sbjct: 228 VEIKVADIQNSPPEF-LDSLTGVVREDDPIGTLVMTVKARDGDRGMPRKMIYELVTNPFD 286
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSS----LRMKVYAKE 385
F +D +G L R L+REA L +KV A+E
Sbjct: 287 YFLLDDETGEL--RTAKPLNREALKDSTGVLTLKVRARE 323
>UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 4187
Score = 138 bits (333), Expect = 1e-30
Identities = 180/697 (25%), Positives = 308/697 (44%), Gaps = 61/697 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G +RY L N R + F ++ G + LD D N LQV
Sbjct: 448 VSAEDLDSGGNGKVRYSL--ANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFIN---LQV 502
Query: 277 QASQLNNPLKT-AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+AS PL+ + V++ + ++NDN P + NI + N P G + V A D D
Sbjct: 503 RASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDIDI 562
Query: 336 GENGE---FTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKE---TNP 388
+ + + + AFS+DP++G L T R+ L RE ++ +E T+P
Sbjct: 563 SDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSLRGLQREFTLIIKATDGIQESPDTHP 622
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
++ R A+ + + T ++ Y K+ K E Y Q + F ++
Sbjct: 623 VILKISIVGGRQARKLQNHVSTKC-VDSPLYAKALKI--KQEQKSYSSLQPLIFATAKLH 679
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
N ++PVF S+ + + + TV+ + A D D G NG+VLY + +
Sbjct: 680 ----NRHHPVF-RSHDQNIHISESTPIATVVSQFMATDEDKGYNGLVLYSIVEGD---VD 731
Query: 509 SPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
S F IN TG ++VA E + L + A D R+ + ++ +++T +
Sbjct: 732 SVFNINMFTGELTVAMPLDRETISSYTLNISAVD---CGKHRKSAYTILNVKITDVNDCS 788
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEE 624
P F YE + N+ +G +V + +D + + ++Y +++ + G F V
Sbjct: 789 ----PVFDKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQIVNDF--GGKFRVNR 842
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV--TNATVHVVDVNDERGVLLKGAHS 682
SGV++V D L + MY E A+ + + V T+ V ++D+ND ++ +
Sbjct: 843 ISGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVKPKKFN 902
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQ 741
+ ++ A + I ++ S G G G + F + + T I ++ G I +
Sbjct: 903 VTV--QEDLLVNAVVTSIHASDPDS--GPG-GEIEFSL---PESTRKFNIDSKSGVIRLR 954
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHA-TYEGFIME 798
+ LD E++ Y +TV +KG + +V + + D N+N PVF E I E
Sbjct: 955 QRLDFEQKSTYNLTVRVT-DKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILETSINE 1013
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
NS +GT + KATD D L + G G + F +D +TG ++ G+ LD E
Sbjct: 1014 NSPVGTVVISP---KATDQDSW--YLKYAIIDGTGVDKFIIDPDTGAIRTAGE-LDHEVA 1067
Query: 859 IMYKLSLVARD--TGGLSSEAELIIMIGDENDNKPEF 893
Y L++ A+D + L + ++I I D ND P F
Sbjct: 1068 DHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYF 1104
Score = 136 bits (330), Expect = 3e-30
Identities = 129/463 (27%), Positives = 215/463 (46%), Gaps = 33/463 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V++T+L+ D + + Y+ ++ NA++G ++ + V P G V Y
Sbjct: 2631 LRSIASVKITVLE-RDARILHFGKSKYDVTVGENAEMGQIVTGLNLVVPG-GNPVDVDYR 2688
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
+ + +N F ++ +TG V V E R+ + VEA+ N R + V
Sbjct: 2689 IIKGNNDNNDRKFGVD-STGRVRVIGRLDYEIRNRYVMIVEANVSAINQIARTV-VVVQV 2746
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGY 614
+++ T P F+ PY + N+ IG+ V ++ D ++ V+Y L+
Sbjct: 2747 LDINDVT-------PKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKD 2799
Query: 615 E-EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
+ F +++ +G IT L R +P ++F+ A L+ +T V+DVND
Sbjct: 2800 KLVKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDT 2859
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
K + S + VKE+ A IGQ T ++ T F+++ I
Sbjct: 2860 PP---KFSQSEFMASVKED---ALIGQSVTTITATDEDLNTELYYFILSGDPQARFGIE- 2912
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G IF LDRE Y + + A + G+ + Q+ I IED NDNPP+ + Y
Sbjct: 2913 RKTGVIFVHGSLDRESVGSYDLNISA--SDGLFTSFA--QMKIDIEDANDNPPICTQSIY 2968
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I EN+ +G+ + + ATDAD G NA Y++FG+G F VD+N + +
Sbjct: 2969 VEHIKENTPLGSTVLT---VGATDADVGVNAELTYSVFGQGFGTFAVDKNGKMTNLV--E 3023
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
LDRE + Y + A D GG + + + I + D NDN+P F+Q
Sbjct: 3024 LDRETRPFYNFMVSAADIGGQACYSNISIHLDDVNDNRPLFSQ 3066
Score = 135 bits (327), Expect = 8e-30
Identities = 246/1039 (23%), Positives = 413/1039 (39%), Gaps = 116/1039 (11%)
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
Q L +A + + T V D+ ++ + QL+ VNV+ N +P F S
Sbjct: 164 QKLSNSARIHRLTVVARDRALPPSKPKSSRNCQLI--VNVQAV----NQFSPEF--SVKT 215
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA-- 523
+ S G V + +D D G NG + + NL K +PN V V
Sbjct: 216 QLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAVQVIKP 275
Query: 524 -ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
+ + + + + A D+ Y L V ++ + P+F + Y +
Sbjct: 276 LDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLD-------ENDNNPEFNQSRYITNL 328
Query: 583 GSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNR 640
I T V ++ D A ++ Y + G E G F + ++G I DL +R
Sbjct: 329 SELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELG-KFEINSKTGQIYTKGDLDYESR 387
Query: 641 PMYDFEAVALQ----ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
+D AL ++ +S V V+++D ND + ++ ++ + G +
Sbjct: 388 QRFDLTVAALDGVPLQSRKISTVP-VVVNILDANDHDPEFKAPEYRKDLY--EDLTPGTS 444
Query: 697 IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKR--DVYRM 754
+ F + + G G VR+ +AN + V +I + G I T LDR+ + +
Sbjct: 445 V---FTVSAEDLDSGGNGKVRYSLANLRPVPFEIE-PDTGIIRTTTNLDRDTGLPEFINL 500
Query: 755 TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
V A + V + +++ NDN PV + + N+ +G I I
Sbjct: 501 QVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDI 560
Query: 815 TDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD--SLDREKKIMYKLSLVARDTGG 872
+D+ + ++ T FG + F +D TG ++ L RE ++ K + +++
Sbjct: 561 DISDKDQSLMYKST-FGNTGKAFSLDPKTGELRTARSLRGLQREFTLIIKATDGIQESPD 619
Query: 873 LSSEAELIIMIGDENDNKPEFNQIEEN--------SKVRIHRETK-LNGTAGFTIIEVKP 923
I ++G K + N + ++I +E K + K
Sbjct: 620 THPVILKISIVGGRQARKLQ-NHVSTKCVDSPLYAKALKIKQEQKSYSSLQPLIFATAKL 678
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
N+ I E+ PI T + + A D D G NG + Y S +
Sbjct: 679 HNRHHPVFRSHDQNIHISESTPIATVVSQFMATDEDKGYNGLVLY----------SIVEG 728
Query: 984 DALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDN--ISVRVFVKDVN 1039
D V F IN G + VA L E S + LNISA+D G + + V + DVN
Sbjct: 729 D---VDSVFNINMFTGELTVAMPLDRETISSYTLNISAVDCGKHRKSAYTILNVKITDVN 785
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT 1099
D PVF KT Y + E + + V A+D D G N +TY I +D F ++ ++
Sbjct: 786 DCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQI-VNDFGGKFRVNRIS 844
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP--KFYAFDEL 1157
GV+SV LD E ++ Y + + A D+ D+NDNSP K F+
Sbjct: 845 GVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNVT 904
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILY 1216
+ + D L N S+ A+ ++ P G + + F I + +G+I
Sbjct: 905 V-----QEDLLVNAVVTSI------HASDPDSGPGGEIEFSLPESTRKFNIDSKSGVIRL 953
Query: 1217 SLP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFI-SRYYELE 1265
++K+ NL G P+L + ++V V DV E S PVF R E
Sbjct: 954 RQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDVN---ENSLAPVFSGGRILETS 1010
Query: 1266 IEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
I EN ++S T+ +++ ++Y I++ D F+IDP G + D EV
Sbjct: 1011 INENSPVGTVVISPKATDQ-DSWYLKYAIIDGTGVD---KFIIDPDTGAIRTAGELDHEV 1066
Query: 1326 KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNR 1385
D Y + V+A+ + YP+ ++ V++ I D+ND +P F
Sbjct: 1067 ADHYWLTVQAKDGE--------SYPLYT---------NIPVLINIVDLNDEAPYFAPSTY 1109
Query: 1386 PLVTAIPTTAPFGYQVMQL 1404
V A P G V+Q+
Sbjct: 1110 YPVLA--ENLPSGSSVVQV 1126
Score = 124 bits (300), Expect = 1e-26
Identities = 136/515 (26%), Positives = 225/515 (43%), Gaps = 42/515 (8%)
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
+ VG+ NI D SF +++ + DANDN P+ S +Y +K N +G+ + V
Sbjct: 2927 ESVGSYDLNISASDGLFTSFAQMKIDIEDANDNPPICTQS-IYVEHIKENTPLGSTVLTV 2985
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD 540
A D D+G N + Y + T F ++ N ++ E E R + V A+D
Sbjct: 2986 GATDADVGVNAELTYSVFGQGFGT----FAVDKNGKMTNLVELD-RETRPFYNFMVSAAD 3040
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
S+ + + R P F + Y V + + + Q++ +DA
Sbjct: 3041 IGGQACYSNISIHLDDVNDNR---------PLFSQSSYFTAVYEDAPLKKVLLQVKADDA 3091
Query: 601 FE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LS 657
++Y L+ + G F +E +G+I++ L+R + Y + LS
Sbjct: 3092 DVGVNRKLTYSLVT--DAGGTFTIETGTGIISLEKPLNRELKENYTLNVEVMDGGTPPLS 3149
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
+ + V+++ND V + +HS I+H S A IG + + +
Sbjct: 3150 SIATVQIKVLNIND---VPPEFSHS--IYHGNV-SEDAPIGNEVVRVRAVSRESSNDVIT 3203
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ I D ++GTI + LD E +Y +TV A + + Y V I +
Sbjct: 3204 YAILRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSY-VRISV 3262
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEM 836
D NDN P F Y + ENS +GT + + ATD D GTNA Y++ G +
Sbjct: 3263 TDSNDNGPEFSEKRYSAKVDENSALGTFVLQ---VFATDRDSGTNAQIKYSIAEGNDAKK 3319
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--IMIGDENDNKPEFN 894
F + E TGV+K GD +DRE+ Y+L + A+D G A+ + I + D NDN PEF+
Sbjct: 3320 FKIVEETGVIKVSGD-IDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEFS 3378
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFAL 929
+ + E+ L A +I ++P ++ AL
Sbjct: 3379 ---STNLTTVLSESSLPNAA---VIHLRPHDRDAL 3407
Score = 123 bits (296), Expect = 4e-26
Identities = 128/456 (28%), Positives = 208/456 (45%), Gaps = 34/456 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD ND P FV S+ Y S+ N +G+ + +V A D D G NGMV Y L
Sbjct: 2742 VVVQVLDINDVTPKFV-SDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKDK 2800
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEVTRG 562
L + F I+ +TG ++ + E + + V A+D N + R SL V V
Sbjct: 2801 L-VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATD---NGTTRLTSLTTVRAIVL-- 2854
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P F + + V + IG SV I D ++ Y +L G + F +
Sbjct: 2855 DVNDTP--PKFSQSEFMASVKEDALIGQSVTTITATDEDLNTELYYFILSG-DPQARFGI 2911
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
E ++GVI V L R + YD A + + + + D ND + + +
Sbjct: 2912 ERKTGVIFVHGSLDRESVGSYDLNISA--SDGLFTSFAQMKIDIEDANDNPPICTQSIY- 2968
Query: 683 PIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ H+KEN+ G+ + + T+ + + N + + + Q T A+ ++G +
Sbjct: 2969 --VEHIKENTPLGSTVLTVGATD-ADVGVNA--ELTYSVFGQGFGT--FAVDKNGKMTNL 3021
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQ-VTIYIEDENDNPPVFEHATYEGFIMENS 800
LDRE R Y V A I G Y ++I+++D NDN P+F ++Y + E++
Sbjct: 3022 VELDRETRPFYNFMVSA----ADIGGQACYSNISIHLDDVNDNRPLFSQSSYFTAVYEDA 3077
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
+ + +KA DAD G N Y+L + F ++ TG++ + L+RE K
Sbjct: 3078 PLKKVLLQ---VKADDADVGVNRKLTYSLVTDAGGTFTIETGTGIIS-LEKPLNRELKEN 3133
Query: 861 YKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
Y L++ D G LSS A + I + + ND PEF+
Sbjct: 3134 YTLNVEVMDGGTPPLSSIATVQIKVLNINDVPPEFS 3169
Score = 119 bits (286), Expect = 7e-25
Identities = 164/697 (23%), Positives = 282/697 (40%), Gaps = 71/697 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D G + Y + GN+ F ++S G ++ + +LD ++ L
Sbjct: 343 ATDKDAGSNGNIMYVITRGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPL 402
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
Q K + V + +LD ND+ PEF+ Y + E+L G SV V A D D G NG
Sbjct: 403 QSR---KISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNG 459
Query: 340 EFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREA--HSSLRMKVYAKETNPSVVGTFAD 396
+ Y L + + F I+P +G +R T LDR+ + ++V A + + +
Sbjct: 460 KVRYSLANLRPVPFEIEPDTG--IIRTTTNLDRDTGLPEFINLQVRASDFGTPL---RRE 514
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
++ + K R + + NAP+ K NI + + VT +D + ++
Sbjct: 515 TETLVKMRVKEMNDNAPVLKQFKC----------NILVDRNAPVGVLITTVTAIDIDISD 564
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ--NGMVLYDLQRTSNLTI--TSPFK 512
+ S+ + G GK ++DP G+ L LQR L I T +
Sbjct: 565 K--------DQSLMYKSTFGNT-GKAFSLDPKTGELRTARSLRGLQREFTLIIKATDGIQ 615
Query: 513 INPNTGTVSVAESPILEGRHA------LFVEASDQP-------ANPSERRYSLAVVTIEV 559
+P+T V + + I+ GR A + + D P ++ YS I
Sbjct: 616 ESPDTHPV-ILKISIVGGRQARKLQNHVSTKCVDSPLYAKALKIKQEQKSYSSLQPLIFA 674
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG 617
T K + P F + + I T V Q D + + V Y ++ G +
Sbjct: 675 T--AKLHNRHHPVFRSHDQNIHISESTPIATVVSQFMATDEDKGYNGLVLYSIVEGDVDS 732
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVL 676
V F + +G +TV L R Y A+ S T V + DVND V
Sbjct: 733 V-FNINMFTGELTVAMPLDRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVF 791
Query: 677 LKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE- 734
K + + EN +GQ + H + S G + + I N D +
Sbjct: 792 DKTVYEVTL---PEN---ITVGQTVTHVHASDKDQGTNGFITYQIVN--DFGGKFRVNRI 843
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G + LD E++++Y++ + A + G V + + D NDN P+ + +
Sbjct: 844 SGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNV 903
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ E+ + + I A+D D G ++L E F++D +GV++ + LD
Sbjct: 904 TVQEDLLVNAVV---TSIHASDPDSGPGGEIEFSL-PESTRKFNIDSKSGVIR-LRQRLD 958
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
E+K Y L++ D G L ++ E+++ + D N+N
Sbjct: 959 FEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDVNEN 995
Score = 115 bits (277), Expect = 9e-24
Identities = 120/463 (25%), Positives = 202/463 (43%), Gaps = 35/463 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ +NV++T D ND +PVF +YE ++ N VG + V A D D G NG + Y +
Sbjct: 775 TILNVKIT--DVNDCSPVF-DKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQIV 831
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F++N +G VSV + E + +E ++ ++ V + +
Sbjct: 832 N----DFGGKFRVNRISGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLL 887
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGV 618
N P + + V ++ + V I + D+ ++ + L E
Sbjct: 888 -DINDNSPIVKP---KKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSL---PESTR 940
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN--ATVHVVDVNDERGVL 676
F ++ +SGVI + L + Y+ V + + + ++ T+ V+V+DVN+
Sbjct: 941 KFNIDSKSGVIRLRQRLDFEQKSTYNL-TVRVTDKGSPALFTDVEVVVNVLDVNENSLAP 999
Query: 677 LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ + + ENS G + T+ S Y +++ I + V I +
Sbjct: 1000 VFSGGRILETSINENSPVGTVVISPKATDQDSWY------LKYAIIDGTGVDKFIIDPDT 1053
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T LD E D Y +TV A+ + I V I I D ND P F +TY
Sbjct: 1054 GAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNI-PVLINIVDLNDEAPYFAPSTYYPV 1112
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLD 854
+ EN G+ + + A D D G +L YT+ G + F +D +G++ + LD
Sbjct: 1113 LAENLPSGSSVVQ---VTAKDPDSG-GSLLRYTITKGNEQNNFVIDPQSGLITTL-RPLD 1167
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
RE K YKL++ A D G +S++ + I DENDN+PEF +
Sbjct: 1168 REFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQPEFKE 1210
Score = 115 bits (276), Expect = 1e-23
Identities = 113/466 (24%), Positives = 200/466 (42%), Gaps = 33/466 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D Q + +V VTLLD NDN+P+ P + +++ + V V+ + A DPD G G +
Sbjct: 873 DNQKVGSTHVIVTLLDINDNSPIVKPKK-FNVTVQEDLLVNAVVTSIHASDPDSGPGGEI 931
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
+ L + T F I+ +G + + + E + + L V +D+ + +
Sbjct: 932 EFSLPES-----TRKFNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVV 986
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V ++V + P F G E + N +GT V + D + + Y ++
Sbjct: 987 VNVLDVNENSLA-----PVFSGGRILETSINENSPVGTVVISPKATDQ-DSWYLKYAIID 1040
Query: 613 GYEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN--ATVHVVDV 669
G GV F ++ +G I +L Y + V ++ + + TN +++VD+
Sbjct: 1041 G--TGVDKFIIDPDTGAIRTAGELDHEVADHY-WLTVQAKDGESYPLYTNIPVLINIVDL 1097
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
NDE + P++ + +G+++ Q+ + S G +R+ I + +
Sbjct: 1098 NDEAPYFAPSTYYPVL--AENLPSGSSVVQVTAKDPDS----GGSLLRYTITKGNEQNNF 1151
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ + G I T +PLDRE + Y++TV A + G + T+ I DENDN P F+
Sbjct: 1152 VIDPQSGLITTLRPLDREFKSEYKLTVSAS-DGGTPPVSTDVTFTVKITDENDNQPEFKE 1210
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKF 848
Y + + ++ ATD D G+NA Y++ G F +D +G +
Sbjct: 1211 KQYVVGVFARQATSKSFGLYQVV-ATDEDIGSNADLRYSITKGNRDNKFIIDSRSGEIFT 1269
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
+D E Y L++VA D G ++I NKP N
Sbjct: 1270 NVSLVDGES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKN 1312
Score = 113 bits (273), Expect = 3e-23
Identities = 124/465 (26%), Positives = 202/465 (43%), Gaps = 38/465 (8%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ N+ + L D NDN P+F S+ Y ++ +A + V+ +VKA D D+G N + Y L
Sbjct: 3047 YSNISIHLDDVNDNRPLFSQSS-YFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT 3105
Query: 502 TSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ T F I TG +S+ E P+ L+ + L VE D P S+A V I+
Sbjct: 3106 DAGGT----FTIETGTGIISL-EKPLNRELKENYTLNVEVMDGGTPPLS---SIATVQIK 3157
Query: 559 VTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV-SYDLLHGYEE 616
V N D+ P+F + Y V + IG V ++R NDV +Y +L G +
Sbjct: 3158 VL-----NINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRESSNDVITYAILRGADS 3212
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGV 675
G+ F+++ ++G I V L +Y A L + + V D ND
Sbjct: 3213 GL-FSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDSNDNGPE 3271
Query: 676 LLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ +S V ENSA G + Q+F T+ S +++ IA D + E
Sbjct: 3272 FSEKRYSA---KVDENSALGTFVLQVFATDRDS---GTNAQIKYSIAEGNDAKKFKIVEE 3325
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I +DRE+ YR+ V A+ ++G+ V I + D NDN P F
Sbjct: 3326 TGVIKVSGDIDREEVASYRLKVRAQ-DQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTT 3384
Query: 795 FIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
+ E+S + ++ D D G A + +TL F + N G++ IGD
Sbjct: 3385 VLSESSLPNAAVIH---LRPHDRDALGNGAPYQFTLISGDASRFKLHSN-GLITKIGDVS 3440
Query: 854 DREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
+ + Y+L ++ D G S+E + + I + + P + +
Sbjct: 3441 HSDGQ--YRLRVLVADNGHPPQSTEVSITVKIAESKTHPPNVHPL 3483
Score = 110 bits (265), Expect = 2e-22
Identities = 122/477 (25%), Positives = 206/477 (43%), Gaps = 43/477 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+E D + V V + +LD NDN+P Y + N+ VGT++ VK DPD G
Sbjct: 1388 VEATDGYNTASVPVTINILDVNDNSPQPARRE-YRAHVAENSDVGTLVTTVK--DPDAGV 1444
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERR 549
NG V Y + +T+ S FKI ++G + + E H L ++ASD+ E
Sbjct: 1445 NGEVEYCIVQTAKAESASLFKIESHSGRILTVKPLDYETMQEHVLTIKASDRGIPKRETL 1504
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
+S+ VV+++ K P+F+ +E V + GT++ ++ D + + +
Sbjct: 1505 FSV-VVSVDDVNDHK------PEFLSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLK 1557
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y ++ G +V++ SGV+ V LS Y + V + + T V V
Sbjct: 1558 YSIVSG-NTNKSLSVDQNSGVVKVAGRLSTLVH-QYALK-VQSTDGGEPPLKTQVDVKV- 1613
Query: 668 DVNDERGVLLKGAHSPIIFHVK--ENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
RG++ A + V ENS AI + + + +Y ++ +
Sbjct: 1614 ---KVRGIVKNFAFEKPKYEVSLPENSPPDQAIATVVYNGILPVYE--------IVPGRS 1662
Query: 725 DVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D + + G I ++K D E+ ++ + A G S V + I+D+NDN
Sbjct: 1663 PCWRDFTVQRQSGVIISKKSFDAEEVTHCKLEIRANSTDGQHSST---LVIVTIQDKNDN 1719
Query: 784 PPVFEHATYEGFIMENSKIGTEI---KMDNIIK-ATDADEGTNALFMYTLFGEGKEMFDV 839
P+FEHA G + E S GT + K ++ ATD D + L + +++F +
Sbjct: 1720 QPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVETSARDVFSI 1779
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
TG + LD E Y + D+G LS+ A++ I + D ND P F+
Sbjct: 1780 HPATGAIT-TAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFS 1835
Score = 109 bits (262), Expect = 6e-22
Identities = 111/436 (25%), Positives = 191/436 (43%), Gaps = 33/436 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYE--FSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
V V + D NDN P F F+ ++ +K + +V A D D+G N + Y +
Sbjct: 1192 VTFTVKITDENDNQPEFKEKQYVVGVFARQATSK-SFGLYQVVATDEDIGSNADLRYSIT 1250
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ + + F I+ +G + S + + L + A D N + + V I+V
Sbjct: 1251 KGNR---DNKFIIDSRSGEIFTNVSLVDGESYDLTIVAED---NGLPKLSTSTNVLIDVI 1304
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+G K +K + P F Y + + I + V I D + + ++Y++ G G F
Sbjct: 1305 QGNKPSK-NAPVFWNKQYSADIQEDKRINSFVLIIGAEDP-DFDQITYNIASG-NHGNKF 1361
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
++ G ITV L R + Y A S+ T++++DVND + A
Sbjct: 1362 TIDRYGGFITVAHSLDREEKSFYSLRVEATDGYNTASVPV--TINILDVNDNSP---QPA 1416
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI---ANQQDVTDDIAIAEDGT 737
HV ENS +G + T + G V + I A + + + G
Sbjct: 1417 RREYRAHVAENSD---VGTLV-TTVKDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGR 1472
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T KPLD E + +T+ A ++G+ ++ V + ++D ND+ P F +E +
Sbjct: 1473 ILTVKPLDYETMQEHVLTIKAS-DRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVD 1531
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDRE 856
++K GT I + ATD D+GTN+ Y++ G + VD+N+GVVK G R
Sbjct: 1532 VSAKAGTAILR---VIATDKDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAG----RL 1584
Query: 857 KKIMYKLSLVARDTGG 872
++++ +L + T G
Sbjct: 1585 STLVHQYALKVQSTDG 1600
Score = 104 bits (249), Expect = 2e-20
Identities = 94/334 (28%), Positives = 152/334 (45%), Gaps = 29/334 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-----IGPSLTIPL 132
+ Y +++++++DVNDN P+F + Y V E P +K + + A + LT L
Sbjct: 3045 ACYSNISIHLDDVNDNRPLFSQSSYFTAVYEDAPL-KKVLLQVKADDADVGVNRKLTYSL 3103
Query: 133 TVPRG--LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
G TI +KP +Y++ DG SS V + KVL+
Sbjct: 3104 VTDAGGTFTIETGTGIISLEKPLNRELKENYTLNVEVMDGGTPPLSSIATVQI--KVLNI 3161
Query: 191 DAGDKEFQLVI----MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
+ EF I ++ I E++ + A+ ++ + Y ++ G D LFS+
Sbjct: 3162 NDVPPEFSHSIYHGNVSEDAPIGNEVV---RVRAVSRESS-NDVITYAILRGADSGLFSI 3217
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D NG++ + ++LD + + L V+AS P+ + + V I + D NDN PEF
Sbjct: 3218 DRKNGTIHVNRKLDYET-----TKLYTLTVEASDAGPPVLRSTSYVRISVTDSNDNGPEF 3272
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVR 364
Y+ + EN G VLQV ATD+D G N + Y + + A F I +G + V
Sbjct: 3273 SEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSIAEGNDAKKFKIVEETGVIKVS 3332
Query: 365 NQTVLDREAHSSLRMKVYAKETN--PSVVGTFAD 396
+DRE +S R+KV A++ P V T D
Sbjct: 3333 GD--IDREEVASYRLKVRAQDQGLPPQVADTVVD 3364
Score = 102 bits (245), Expect = 7e-20
Identities = 121/484 (25%), Positives = 211/484 (43%), Gaps = 37/484 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E D +S V V + D ND++P+F ++Y+ S N GT + V A D D G
Sbjct: 2416 DVEVSDSVHVSTSKVRVIIGDTNDHSPIF-SEDVYKVSFNENYPEGTFVTMVSATDLDSG 2474
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQP--ANPSER 548
+ Y + ++ F+I+ ++G + S ++ R P A
Sbjct: 2475 NYAHLTYSI---DSVDAMRKFRIDADSG---MLYSRLMFDRENSSQAIMSVPIRATDGGG 2528
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
R+ VV + + + P F Y+ + +V +GT V +D ++ +
Sbjct: 2529 RFGFCVVEVHLI----DENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAAL 2584
Query: 609 D-LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
++ G++ F + +GVI V + + Y+F V +++ N + + A+V +
Sbjct: 2585 TYVIVGHQTPPVFTINAATGVIQVSREPEVKS---YNF-FVLVKDGGNPLLRSIASVKIT 2640
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG---NVRFLIANQQ 724
+ + +L G S V EN A +GQI T ++ + G + R + N
Sbjct: 2641 VLERDARILHFG-KSKYDVTVGEN---AEMGQIV-TGLNLVVPGGNPVDVDYRIIKGNND 2695
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ + G + LD E R+ Y M I E N I+ V + + D ND
Sbjct: 2696 NNDRKFGVDSTGRVRVIGRLDYEIRNRYVM--IVEANVSAINQIARTVVVVQVLDINDVT 2753
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG---KEMFDVDE 841
P F Y I EN IG+++ + A D D G+N + Y L + KE FD+D+
Sbjct: 2754 PKFVSDPYLASIPENIDIGSKVLR---VFAEDLDSGSNGMVTYALVSKDKLVKEKFDIDQ 2810
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEEN 899
+TG + G +LDREK+ ++ + A D G L+S + ++ D ND P+F+Q E
Sbjct: 2811 HTGWITTRG-ALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFM 2869
Query: 900 SKVR 903
+ V+
Sbjct: 2870 ASVK 2873
Score = 100 bits (240), Expect = 3e-19
Identities = 126/544 (23%), Positives = 233/544 (42%), Gaps = 44/544 (8%)
Query: 377 LRMKVYAKETNPSVV------GTFA-DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKT 429
L+M VY+K ++ G F+ DS++++ + ++T+ L + + V +
Sbjct: 19 LKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNR------ESVASYE 72
Query: 430 ENIEYYDEQL---MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
N+ D++ + V +T+ D+NDN P+F+ Y ++ + + T I +++AVD
Sbjct: 73 LNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKK-YLKTIPEDIPMHTSIARIEAVD 131
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPANP 545
D+G NG++ Y + T+ F INP +G VSVA+ R H L V A D+ P
Sbjct: 132 ADVGPNGLIYYSFKEK-----TTSFAINPISGVVSVAQKLSNSARIHRLTVVARDRALPP 186
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
S+ + S I + P+ + + GI + I D D
Sbjct: 187 SKPKSSRNCQLIVNVQAVNQFSPEFS--VKTQLQNVSEGTSGIVYATLGIIDKDKGSNGD 244
Query: 606 VS-YDLLHGYEEGVPFAVEERSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
+ ++ G +G F+++ + V+ L R P + + + + +
Sbjct: 245 IDRVEITSGNLDGA-FSIKSSPNDYAVQVIKPLDRELAP-FGYNVTLTAYDKGTPVRNGS 302
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
V V+V DE + S I ++ E + + ++ T+ + GN+ ++I
Sbjct: 303 YVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDA---GSNGNIMYVIT 359
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS-GAGIYQVTIYIEDE 780
++ ++ G I+T+ LD E R + +TV A + S V + I D
Sbjct: 360 RGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDA 419
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
ND+ P F+ Y + E+ GT + + A D D G N Y+L F+++
Sbjct: 420 NDHDPEFKAPEYRKDLYEDLTPGTSV---FTVSAEDLDSGGNGKVRYSLANLRPVPFEIE 476
Query: 841 ENTGVVKFIGDSLDREKKI--MYKLSLVARDTG-GLSSEAELII--MIGDENDNKPEFNQ 895
+TG+++ +LDR+ + L + A D G L E E ++ + + NDN P Q
Sbjct: 477 PDTGIIR-TTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQ 535
Query: 896 IEEN 899
+ N
Sbjct: 536 FKCN 539
Score = 100 bits (240), Expect = 3e-19
Identities = 110/449 (24%), Positives = 200/449 (44%), Gaps = 42/449 (9%)
Query: 460 VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP---FKINPN 516
+PS+ +FS K+ + + + +VD +L + Y + T TI +P F I P+
Sbjct: 1925 LPSSDLQFSRKNYS---ASVREGVSVDSELVTVRALGYPIGSTITYTIINPSELFHIVPS 1981
Query: 517 TGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
TG +S+ L+ + + V+A D P+ + ++ V I+ + P
Sbjct: 1982 TGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVID-------RNDNQPV 2034
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
F+ +PY + V GT +GQ + DA ++ YDL+ G + G F++ ++G +
Sbjct: 2035 FINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGG-DPGY-FSISRKTGEVV 2092
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
V L P + E + T A V + V+ E V + + S ++ ++
Sbjct: 2093 VRRTLDDVKVPRL---FTLMVEATDGLFRTEAVVKIKVVDKETPVFDQLSFSKVL--AED 2147
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
G+ + T++++ NG G + + I V + G + LD E R
Sbjct: 2148 TPIGSEV-----TSVTARSPNGAG-ILYSITGGDPVNQFSIDFKTGVVTLVSSLDYETRT 2201
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN 810
Y++ V A + S V + + D ND P F + Y I E++ + T +
Sbjct: 2202 KYKLVVRATDAR--TSSHSDVAVDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVT-- 2257
Query: 811 IIKATDADEGTNALFMYTLFGEGK--EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
+KA D D G N Y + + F +D+ +GVV F+ SLD E ++++++ +VA
Sbjct: 2258 -VKAIDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVV-FVAKSLDYESRVVHEMIIVAA 2315
Query: 869 DTG--GLSSEAELIIMIGDENDNKPEFNQ 895
D G L+ E + +++ D NDN P F++
Sbjct: 2316 DEGKPSLTGETRVRVVLMDANDNAPRFDK 2344
Score = 100 bits (240), Expect = 3e-19
Identities = 112/439 (25%), Positives = 202/439 (46%), Gaps = 37/439 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V+VT+ D ND P F S LY ++ + V T + VKA+D D G N + Y +Q
Sbjct: 2218 SDVAVDVTVTDVNDVAPAFNRS-LYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQ 2276
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQ--PANPSERRYSLAVVT 556
S + + FKI+ +G V VA+S E R H + + A+D+ P+ E R + VV
Sbjct: 2277 NVSR--VGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETR--VRVVL 2332
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGY 614
++ + P F + Y + + G V +I D E + + Y + G
Sbjct: 2333 MDAN-------DNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGG- 2384
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+ F ++ +SGVIT+ + +Y + V + ++ ++S + V + D ND
Sbjct: 2385 QGRQHFQIDSQSGVITLSRVVGIKQGKVYGLD-VEVSDSVHVS-TSKVRVIIGDTNDHSP 2442
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ + + + F+ + G + + T++ S GN ++ + I + + A+
Sbjct: 2443 IFSEDVYK-VSFN-ENYPEGTFVTMVSATDLDS--GN-YAHLTYSIDSVDAMRKFRIDAD 2497
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G ++++ DRE M+V G G V +++ DENDN P+FE Y+
Sbjct: 2498 SGMLYSRLMFDRENSSQAIMSVPIRATDGG-GRFGFCVVEVHLIDENDNQPIFELKNYDT 2556
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSL 853
I + +GT + M + A+D D +NA Y + G + +F ++ TGV++ +
Sbjct: 2557 TISRSVTMGTPVLMTS---ASDPDASSNAALTYVIVGHQTPPVFTINAATGVIQ-----V 2608
Query: 854 DREKKI-MYKLSLVARDTG 871
RE ++ Y ++ +D G
Sbjct: 2609 SREPEVKSYNFFVLVKDGG 2627
Score = 98.7 bits (235), Expect = 1e-18
Identities = 120/464 (25%), Positives = 195/464 (42%), Gaps = 38/464 (8%)
Query: 439 LMSFVNVEVTLLDANDNN--PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
L + V V V +LD N+N+ PVF + E S+ N+ VGTV+ KA D D +
Sbjct: 979 LFTDVEVVVNVLDVNENSLAPVFSGGRILETSINENSPVGTVVISPKATDQDSWYLKYAI 1038
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
D T F I+P+TG + A E + L V+A D + P + +
Sbjct: 1039 ID------GTGVDKFIIDPDTGAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNIPVLI 1092
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLHG 613
+++ + P F + Y + N+ G+SV Q+ D + Y + G
Sbjct: 1093 NIVDL-------NDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGGSLLRYTITKG 1145
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVND 671
E+ F ++ +SG+IT + L R + Y V+ + + T+ TV + D ND
Sbjct: 1146 NEQN-NFVIDPQSGLITTLRPLDREFKSEYKL-TVSASDGGTPPVSTDVTFTVKITDEND 1203
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + + +F + S + Q+ T+ I N ++R+ I I
Sbjct: 1204 NQPEFKEKQYVVGVFARQATSKSFGLYQVVATD-EDIGSN--ADLRYSITKGNRDNKFII 1260
Query: 732 IAEDGTIFTQKPL-DREKRDVYRMTVIAEFN--KGVISGAGIYQVTIYIEDENDNPPVFE 788
+ G IFT L D E Y +T++AE N + + + I + N PVF
Sbjct: 1261 DSRSGEIFTNVSLVDGES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFW 1317
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y I E+ +I + + II A D D + + G F +D G +
Sbjct: 1318 NKQYSADIQEDKRINSFVL---IIGAEDPD--FDQITYNIASGNHGNKFTIDRYGGFIT- 1371
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
+ SLDRE+K Y L + A D G ++ + I I D NDN P+
Sbjct: 1372 VAHSLDREEKSFYSLRVEATD-GYNTASVPVTINILDVNDNSPQ 1414
Score = 94.3 bits (224), Expect = 2e-17
Identities = 76/232 (32%), Positives = 106/232 (45%), Gaps = 28/232 (12%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ + P F+ IPENI IG+ ++++ A DLDSG NG + Y +
Sbjct: 2747 LDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYAL----------V 2796
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKD 1037
S D L VK F I++ G + +L E + F + A D G L +VR V D
Sbjct: 2797 SKDKL-VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLD 2855
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND P F ++ + +V+E + + + ATD D N L YFI D F I
Sbjct: 2856 VNDTPPKFSQSEFMASVKEDALIGQSVTTITATDEDL--NTELYYFILSGDPQARFGIER 2913
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
TGV+ V+G LDRE+ Y L + A D D NDN P
Sbjct: 2914 KTGVIFVHGSLDRESVGSYDLNISASDG----LFTSFAQMKIDIEDANDNPP 2961
Score = 94.3 bits (224), Expect = 2e-17
Identities = 116/456 (25%), Positives = 196/456 (42%), Gaps = 57/456 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P+G+T++ + A D D G+N ++ Y + + + D K + N
Sbjct: 2972 IKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGF---GTFAVD----KNGKMTNL--- 3021
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
V + R P F ++ + + G NIS+ + DVND+ P+F ++ Y V E
Sbjct: 3022 -VELDRETRPFYNFMVSAADIGGQACYSNISIHL--DDVNDNRPLFSQSSYFTAVYEDAP 3078
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++VL +V A DAD G N LTY + +D F I TG++S+ L+RE ++ Y L
Sbjct: 3079 LKKVLLQVKADDADVGVNRKLTYSL-VTDAGGTFTIETGTGIISLEKPLNRELKENYTLN 3137
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPEADE------LSNH 1171
V D G ++ND P+F + + P +E +S
Sbjct: 3138 VEVMDGG-TPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRE 3196
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFAN-DTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
+ V+ + + I + N D+ LY+L + + G P
Sbjct: 3197 SSNDVITYAILRGADSGLFSIDRKNGTIHVNRKLDY----ETTKLYTLTVEAS--DAGPP 3250
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NF 1288
L ST+ + ++V D D + P F + Y +++EN ++ + T+ N
Sbjct: 3251 VLRSTSYVRISVTDSND-----NGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNA 3305
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
+++Y I ND + F I G + + DRE +Y + VRA+ Q LP
Sbjct: 3306 QIKYSIAEGNDA---KKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQ----GLPPQ- 3357
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
VA+ V++ + + DVNDNSP+F++ N
Sbjct: 3358 --VADTVVD----------IEVTDVNDNSPEFSSTN 3381
Score = 89.8 bits (213), Expect = 5e-16
Identities = 118/472 (25%), Positives = 193/472 (40%), Gaps = 51/472 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + V + ++D ND P F PS Y + N G+ + +V A DPD G ++ Y
Sbjct: 1084 LYTNIPVLINIVDLNDEAPYFAPSTYYPV-LAENLPSGSSVVQVTAKDPDSG-GSLLRYT 1141
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
+ + + + F I+P +G ++ P+ + + L V ASD P +
Sbjct: 1142 ITKGNE---QNNFVIDPQSGLITTLR-PLDREFKSEYKLTVSASDGGTPPVSTDVTF--- 1194
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV----NDAFEQNDVSYDLL 611
T+++T + P+F Y V + S G +V D D+ Y +
Sbjct: 1195 TVKIT----DENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSIT 1250
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDV 669
G + F ++ RSG I ++S + YD VA ++N LS TN + V+
Sbjct: 1251 KGNRDN-KFIIDSRSGEIFT--NVSLVDGESYDLTIVA-EDNGLPKLSTSTNVLIDVIQG 1306
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG--NVRFLIANQQDVT 727
N K + + +F K+ SA + ++ + I + + IA+
Sbjct: 1307 N-------KPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFDQITYNIASGNHGN 1359
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G I LDRE++ Y + V A S VTI I D NDN P
Sbjct: 1360 KFTIDRYGGFITVAHSLDREEKSFYSLRVEATDGYNTAS----VPVTINILDVNDNSPQP 1415
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY----TLFGEGKEMFDVDENT 843
Y + ENS +GT + +K D D G N Y T E +F ++ ++
Sbjct: 1416 ARREYRAHVAENSDVGTLV---TTVK--DPDAGVNGEVEYCIVQTAKAESASLFKIESHS 1470
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEF 893
G + + LD E + L++ A D G E +++ + D ND+KPEF
Sbjct: 1471 GRILTV-KPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEF 1521
Score = 84.6 bits (200), Expect = 2e-14
Identities = 90/319 (28%), Positives = 135/319 (42%), Gaps = 25/319 (7%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS-LTIPLT-----V 134
++V V + DVND P F + Y T+ E TP + A + + A G S + + V
Sbjct: 2220 VAVDVTVTDVNDVAPAFNRSLYLATISESTPV-DTAVVTVKAIDGDSGINKEINYFIQNV 2278
Query: 135 PRGLTIFK-DIRA---FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
R FK D ++ F + + VH I+ D+G +L + ++L D
Sbjct: 2279 SRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDN 2338
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+ G + F I A D D G LRY + G R+ F +DS +
Sbjct: 2339 APRFDKSMYAASILGSASPGQ--FVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDSQS 2396
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + L + + + Q + L V+ S + + + ++V + + D ND+ P F D
Sbjct: 2397 GVITLSRVVGIK-----QGKVYGLDVEVS---DSVHVSTSKVRVIIGDTNDHSPIFSEDV 2448
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTV 368
Y +S EN P G V V ATD D G TY +D D F ID SG L R +
Sbjct: 2449 YKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSGMLYSR--LM 2506
Query: 369 LDREAHSSLRMKVYAKETN 387
DRE S M V + T+
Sbjct: 2507 FDRENSSQAIMSVPIRATD 2525
Score = 81.4 bits (192), Expect = 2e-13
Identities = 127/496 (25%), Positives = 206/496 (41%), Gaps = 73/496 (14%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL--------IPENIPIGTTIIKLNALD 957
R T A FT +EV N ++ + L P+F I EN P+GT +I A D
Sbjct: 970 RVTDKGSPALFTDVEVVV-NVLDVNENSLAPVFSGGRILETSINENSPVGTVVISPKATD 1028
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRL 1015
DS ++Y D V + F+I+ G + A L E + L
Sbjct: 1029 QDSWY---LKYAI------------IDGTGVDK-FIIDPDTGAIRTAGELDHEVADHYWL 1072
Query: 1016 NISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
+ A DG + L NI V + + D+ND P F + Y + E + + +V A D D
Sbjct: 1073 TVQAKDGESYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPD 1132
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
G + L Y I + F I P +G+++ LDRE + +Y LTV A D G
Sbjct: 1133 SGGSL-LRYTITKGNEQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGG-TPPVST 1190
Query: 1134 XXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG 1193
D NDN P+F ++ A + ++ +F + + I NA +
Sbjct: 1191 DVTFTVKITDENDNQPEFKEKQYVV---GVFARQATSKSF-GLYQVVATDEDIGSNADLR 1246
Query: 1194 TTVAKVFANDTDFIGNGNGLIL--YSLPQRKN------QQNLGLPSLSSTAILMVTVADV 1245
++ K ++ I + +G I SL ++ ++ GLP LS++ +++ V +
Sbjct: 1247 YSITKGNRDNKFIIDSRSGEIFTNVSLVDGESYDLTIVAEDNGLPKLSTSTNVLIDV--I 1304
Query: 1246 PDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIR 1303
+ PVF ++ Y +I+E+ +N+ V ++ E + ++ Y I + N +
Sbjct: 1305 QGNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIG---AEDPDFDQITYNIASGNHGN-- 1359
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD 1363
F ID G + + S DRE K Y + V A +G
Sbjct: 1360 -KFTIDRYGGFITVAHSLDREEKSFYSLRVEA--------------------TDGYNTAS 1398
Query: 1364 VKVVVRIKDVNDNSPK 1379
V V + I DVNDNSP+
Sbjct: 1399 VPVTINILDVNDNSPQ 1414
Score = 79.0 bits (186), Expect = 9e-13
Identities = 115/464 (24%), Positives = 203/464 (43%), Gaps = 44/464 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L +F +V++ + D ND PVF S Y ++ + GT + V A D D N + +
Sbjct: 1813 RLSAFADVKIHVTDINDIAPVFSAST-YHATVYLPSYAGTRVTMVTATDGDSAAN--LTF 1869
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
L R T F +NP TG V+V+ + +L R ++ + N + A V I
Sbjct: 1870 SLARQD----TELFAVNPLTGVVTVSNAALLR-RDTYTIKLTVSDGNHTAH----ARVRI 1920
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
R D+ F Y V V + + + +R + ++Y +++ E
Sbjct: 1921 ---RCENLPSSDL-QFSRKNYSASVREGVSVDSELVTVRALGYPIGSTITYTIINPSE-- 1974
Query: 618 VPFAVEERSGVITVVD--DLSRYNRPMYDFEAVALQENANLSIVTNAT-VHVVDVNDERG 674
F + +GV+++ DL R + Y A ++ ++ A V V+D ND +
Sbjct: 1975 -LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQP 2033
Query: 675 VLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V + +SP ++ A G IGQ T+ + I N N+R+ + I+
Sbjct: 2034 VFI---NSPYFIVLQLGVAQGTIIGQAQATD-ADIGSN--ANLRYDLIGGDPGYFSIS-R 2086
Query: 734 EDGTIFTQKPLDREKRDVYRM-TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ G + ++ LD K V R+ T++ E G+ + ++ + ++ E PVF+ ++
Sbjct: 2087 KTGEVVVRRTLDDVK--VPRLFTLMVEATDGLFRTEAVVKIKV-VDKET---PVFDQLSF 2140
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ E++ IG+E+ + G L+ T G+ F +D TGVV + S
Sbjct: 2141 SKVLAEDTPIGSEVTS----VTARSPNGAGILYSIT-GGDPVNQFSIDFKTGVVTLV-SS 2194
Query: 853 LDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEFNQ 895
LD E + YKL + A D S S+ + + + D ND P FN+
Sbjct: 2195 LDYETRTKYKLVVRATDARTSSHSDVAVDVTVTDVNDVAPAFNR 2238
Score = 78.6 bits (185), Expect = 1e-12
Identities = 151/645 (23%), Positives = 259/645 (40%), Gaps = 47/645 (7%)
Query: 445 VEVTLLDANDNNPVF----VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL-YDL 499
V VT+ D NDN P+F + ++ E S + A + ++ AV D +G L Y++
Sbjct: 1709 VIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEI 1768
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
TS + F I+P TG ++ A+ E ++A ++ +D NP R + A V I
Sbjct: 1769 VETSARDV---FSIHPATGAITTAKVLDYEVTPQYAFKIKVTDS-GNP--RLSAFADVKI 1822
Query: 558 EVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
VT + DI P F + Y V GT V + D ++++ L ++
Sbjct: 1823 HVT-----DINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAANLTFSLAR--QD 1875
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
FAV +GV+TV + + R Y + N + +D
Sbjct: 1876 TELFAVNPLTGVVTV-SNAALLRRDTYTIKLTVSDGNHTAHARVRIRCENLPSSD----- 1929
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
L+ + V+E G ++ T + Y G+ + + I N ++ +
Sbjct: 1930 LQFSRKNYSASVRE---GVSVDSELVTVRALGYPIGS-TITYTIINPSELFHIVPSTGVM 1985
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+I LDRE D Y++ V A + V V + + D NDN PVF ++ Y +
Sbjct: 1986 SIRAGFDLDRESIDAYQVIVQAR-DDSVPPNVAQAAVHVQVIDRNDNQPVFINSPYFIVL 2044
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
GT I +ATDAD G+NA Y L G F + TG V + +LD +
Sbjct: 2045 QLGVAQGTIIGQ---AQATDADIGSNANLRYDLIGGDPGYFSISRKTGEV-VVRRTLD-D 2099
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
K+ +L+ T GL E ++ I + P F+Q+ SKV + +T +
Sbjct: 2100 VKVPRLFTLMVEATDGL-FRTEAVVKIKVVDKETPVFDQL-SFSKV-LAEDTPIGSEV-- 2154
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKL-NALDLDSGLNGQIRYEFNSEVY 975
T + + N + G + +I T ++ L ++LD ++ ++
Sbjct: 2155 TSVTARSPNGAGILYSITGGDPVNQFSIDFKTGVVTLVSSLDYETRTKYKLVVRATDART 2214
Query: 976 IPPSKLSAD--ALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDG-GNLNDNISVR 1032
S ++ D +V R ++ P + + A+DG +N I+
Sbjct: 2215 SSHSDVAVDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYF 2274
Query: 1033 V-FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
+ V V F + KK+ F + Y RV+ ++ AD G+
Sbjct: 2275 IQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGK 2319
Score = 77.8 bits (183), Expect = 2e-12
Identities = 103/335 (30%), Positives = 143/335 (42%), Gaps = 34/335 (10%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE-LTPTGEKAFIFLIAP-IGPSLTIPL 132
NQ V V + D+NDN PI ++VTV E L I P GP I
Sbjct: 874 NQKVGSTHVIVTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEF 933
Query: 133 TVPRGLTIFK-DIRAFD---RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
++P F D ++ R + + + V D G AL + + V+ VL
Sbjct: 934 SLPESTRKFNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVV---NVL 990
Query: 189 DYDAGDKEFQLVIMASGKRI-HKEILFPEPI-------HAIDQDLGVGATLRYELISGND 240
D + E L + SG RI I P+ A DQD L+Y +I G
Sbjct: 991 DVN----ENSLAPVFSGGRILETSINENSPVGTVVISPKATDQDSWY---LKYAIIDGTG 1043
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTAQARVEIELLDL 299
F +D G++ ELD H + A+ + L VQA + PL T V I ++DL
Sbjct: 1044 VDKFIIDPDTGAIRTAGELD----HEV-ADHYWLTVQAKDGESYPLYT-NIPVLINIVDL 1097
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-GEFTYQLDDPKGAFSIDPRS 358
ND P F Y + ENLP+G SV+QV A D D G + +T + + F IDP+S
Sbjct: 1098 NDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGGSLLRYTITKGNEQNNFVIDPQS 1157
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
G +T LDRE S ++ V A + V T
Sbjct: 1158 GLITTLRP--LDREFKSEYKLTVSASDGGTPPVST 1190
Score = 76.2 bits (179), Expect = 7e-12
Identities = 57/161 (35%), Positives = 79/161 (49%), Gaps = 18/161 (11%)
Query: 233 YELISGN----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
Y +I GN DRK F +DS G + + LD + + +++ S +N +T
Sbjct: 2687 YRIIKGNNDNNDRK-FGVDST-GRVRVIGRLDYEIRNRY---VMIVEANVSAINQIARTV 2741
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
V +++LD+ND P+F D Y SI EN+ G VL+V A D D G NG TY L
Sbjct: 2742 ---VVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSK 2798
Query: 349 ----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
K F ID +GW+T R LDRE S +V A +
Sbjct: 2799 DKLVKEKFDIDQHTGWITTRG--ALDREKQPSFEFQVRATD 2837
Score = 74.9 bits (176), Expect = 2e-11
Identities = 111/449 (24%), Positives = 190/449 (42%), Gaps = 49/449 (10%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
L I E+ P+ T ++ + A+D DSG+N +I Y F V S++ A +F I++
Sbjct: 2242 LATISESTPVDTAVVTVKAIDGDSGINKEINY-FIQNV----SRVGA-------FFKIDK 2289
Query: 997 RHGHVIVARSLPPESEF--RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ G V VA+SL ES + I A D G +L VRV + D ND+ P F K+ Y
Sbjct: 2290 KSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSMYAA 2349
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
++ + + + ++ ATD D G L Y I F+I +GV++++ + +
Sbjct: 2350 SILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDSQSGVITLSRVVGIKQ 2409
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
Y L V D+ D ND+SP F +++ + N N
Sbjct: 2410 GKVYGLDVEVSDS----VHVSTSKVRVIIGDTNDHSPIF--SEDVYKVSF-------NEN 2456
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDT--DFIGNGNGLILYS--LPQRKN--QQN 1226
+ + + AT ++ + + D F + + +LYS + R+N Q
Sbjct: 2457 YPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSGMLYSRLMFDRENSSQAI 2516
Query: 1227 LGLP--SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLT 1282
+ +P + V +V E ++P+F + Y+ I +V PV + S +
Sbjct: 2517 MSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDP 2576
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD-TYEVIVRAERQKYS 1341
+ N + Y I+ + F I+ G + + R P EVK + V+V+
Sbjct: 2577 DASSNAALTYVIVGHQTPPV---FTINAATGVIQVSREP--EVKSYNFFVLVKDGGNPLL 2631
Query: 1342 RELPHMIYPVAE---DVLE-GMTKYDVKV 1366
R + + V E +L G +KYDV V
Sbjct: 2632 RSIASVKITVLERDARILHFGKSKYDVTV 2660
Score = 74.9 bits (176), Expect = 2e-11
Identities = 97/357 (27%), Positives = 148/357 (41%), Gaps = 34/357 (9%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I + G + V SL ES + LNISA DG +++ ++D ND+ P+ ++
Sbjct: 2909 FGIERKTGVIFVHGSLDRESVGSYDLNISASDG-LFTSFAQMKIDIEDANDNPPICTQSI 2967
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y +++E + V ATDAD G NA LTY + F + G ++ ELD
Sbjct: 2968 YVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFG-TFAVDK-NGKMTNLVELD 3025
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RET Y V A D G DVNDN P F + + +A
Sbjct: 3026 RETRPFYNFMVSAADIG---GQACYSNISIHLDDVNDNRPLF-SQSSYFTAVYEDAPLK- 3080
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNL- 1227
+ ++ + A + N + T A T I G G+I P R+ ++N
Sbjct: 3081 ----KVLLQVKADDADVGVNRKL-TYSLVTDAGGTFTIETGTGIISLEKPLNRELKENYT 3135
Query: 1228 --------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
G P LSS A + + V ++ D P F Y + E+ E+V +
Sbjct: 3136 LNVEVMDGGTPPLSSIATVQIKVLNINDV-----PPEFSHSIYHGNVSEDAPIGNEVVRV 3190
Query: 1280 N-LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ N + Y IL D+ + F ID +NGT+++ R D E Y + V A
Sbjct: 3191 RAVSRESSNDVITYAILRGADSGL---FSIDRKNGTIHVNRKLDYETTKLYTLTVEA 3244
Score = 74.1 bits (174), Expect = 3e-11
Identities = 99/331 (29%), Positives = 145/331 (43%), Gaps = 39/331 (11%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IF---LIAPIGPS 127
+ +NQI+ + V V + D+ND P F+ PY ++ E G K +F L +
Sbjct: 2732 SAINQIARTV-VVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGM 2790
Query: 128 LTIPLTVPRGLTIFK-DIR----------AFDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
+T L L K DI A DR+K P+ + V D+G L S
Sbjct: 2791 VTYALVSKDKLVKEKFDIDQHTGWITTRGALDREKQ--PSFEFQ---VRATDNGTTRLTS 2845
Query: 177 SHKPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
+ VLD D K Q MAS K I A D+DL L Y +
Sbjct: 2846 L---TTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSVTTITATDEDLNT--ELYYFI 2900
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
+SG+ + F ++ G +F+ LD ++ ++ L + AS + L T+ A+++I+
Sbjct: 2901 LSGDPQARFGIERKTGVIFVHGSLDRES-----VGSYDLNISAS---DGLFTSFAQMKID 2952
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSI 354
+ D NDN P Y I EN P G +VL V ATD D G N E TY + G F++
Sbjct: 2953 IEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFGTFAV 3012
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D ++G +T N LDRE V A +
Sbjct: 3013 D-KNGKMT--NLVELDRETRPFYNFMVSAAD 3040
Score = 73.7 bits (173), Expect = 3e-11
Identities = 82/315 (26%), Positives = 126/315 (40%), Gaps = 13/315 (4%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTP--TGEKAFIFLIAPIGPSLTIPLTVPRGLTI 140
V + ++D NDN PIFL Y T+ E P T + A +GP+ I + T
Sbjct: 91 VNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS 150
Query: 141 F--KDIRAFDRDKPNTPNSD-VHYSIVSGNDDG-HFALESSHKPVLLLRKVLDYDAGDKE 196
F I NS +H V D + S + L+ V + E
Sbjct: 151 FAINPISGVVSVAQKLSNSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPE 210
Query: 197 FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATL-RYELISGNDRKLFSLDSVNGSLFL 255
F + + + ID+D G + R E+ SGN FS+ S +
Sbjct: 211 FSVKTQLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAV 270
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
+ LD E L + + + A P++ + + +LD NDN PEF Y ++
Sbjct: 271 QVIKPLDRE--LAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNL 328
Query: 316 VENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREA 373
E P VL+V+ATDKD G NG Y + + G F I+ ++G + + LD E+
Sbjct: 329 SELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKTGQIYTKGD--LDYES 386
Query: 374 HSSLRMKVYAKETNP 388
+ V A + P
Sbjct: 387 RQRFDLTVAALDGVP 401
Score = 71.7 bits (168), Expect = 1e-10
Identities = 76/302 (25%), Positives = 131/302 (43%), Gaps = 25/302 (8%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIP 131
+G ++SA+ V +++ D+ND P+F + YH TV + G + + + +
Sbjct: 1809 SGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAANLT 1868
Query: 132 LTVPRGLTIFKDIRAFDRDKPNTPNSDV----HYSIVSGNDDGHFALESSHKPVLLLRKV 187
++ R T + N+ + Y+I DG+ ++H V + +
Sbjct: 1869 FSLARQDTELFAVNPL-TGVVTVSNAALLRRDTYTIKLTVSDGN---HTAHARVRIRCEN 1924
Query: 188 L---DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
L D K + + G + E++ + A+ +G +T+ Y +I N +LF
Sbjct: 1925 LPSSDLQFSRKNYSASV-REGVSVDSELV---TVRALGYPIG--STITYTII--NPSELF 1976
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+ G + + DLD E + + + VQA + P AQA V ++++D NDN P
Sbjct: 1977 HIVPSTGVMSIRAGFDLDRE---SIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQP 2033
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F Y I + + G + Q ATD D G N Y L DP G FSI ++G +
Sbjct: 2034 VFINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDP-GYFSISRKTGEVV 2092
Query: 363 VR 364
VR
Sbjct: 2093 VR 2094
Score = 71.3 bits (167), Expect = 2e-10
Identities = 45/156 (28%), Positives = 77/156 (49%), Gaps = 7/156 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A DQD+ G L YE++ + R +FS+ G++ K LD + + +++ +
Sbjct: 1754 ATDQDIS-GDKLTYEIVETSARDVFSIHPATGAITTAKVLDYEVTPQ-----YAFKIKVT 1807
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP +A A V+I + D+ND P F Y+ ++ G V V ATD D N
Sbjct: 1808 DSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAANL 1867
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
F+ D + F+++P +G +TV N +L R+ ++
Sbjct: 1868 TFSLARQDTE-LFAVNPLTGVVTVSNAALLRRDTYT 1902
Score = 66.5 bits (155), Expect = 5e-09
Identities = 56/191 (29%), Positives = 85/191 (44%), Gaps = 17/191 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +GT + + D D+G+NG++ Y + +K + +L F I G
Sbjct: 1424 VAENSDVGTLVTTVK--DPDAGVNGEVEY-----CIVQTAKAESASL-----FKIESHSG 1471
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ + L E+ E L I A D G SV V V DVNDH P F + V+
Sbjct: 1472 RILTVKPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVD 1531
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ + +V ATD D G N+ L Y I +T+ + +GV+ V G L +
Sbjct: 1532 VSAKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLVH-Q 1590
Query: 1116 YILTVVARDNG 1126
Y L V + D G
Sbjct: 1591 YALKVQSTDGG 1601
Score = 66.1 bits (154), Expect = 7e-09
Identities = 50/164 (30%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGG-NLNDNISVRVFVKDVNDHFPVFKKT 1048
F I+ + G V + SL E+ +++L + A D + + +++V V V DVND P F ++
Sbjct: 2180 FSIDFKTGVVTLVSSLDYETRTKYKLVVRATDARTSSHSDVAVDVTVTDVNDVAPAFNRS 2239
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-PSDTDLPFEISPLTGVLSVNGE 1107
Y + E+ + V A D D G N + YFIQ S F+I +GV+ V
Sbjct: 2240 LYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVVFVAKS 2299
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD E+ + + +VA D G D NDN+P+F
Sbjct: 2300 LDYESRVVHEMIIVAADEG-KPSLTGETRVRVVLMDANDNAPRF 2342
Score = 63.3 bits (147), Expect = 5e-08
Identities = 65/276 (23%), Positives = 120/276 (43%), Gaps = 18/276 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAPIGPSLTIP 131
G +S+ +V + + ++ND P F + YH V E P G + + ++ + I
Sbjct: 3144 GTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVSRESSNDVIT 3203
Query: 132 LTVPRGLT--IF----KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ RG +F K+ K + + ++ V +D G L S+ +
Sbjct: 3204 YAILRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRI--- 3260
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
V D + EF ++ + + F + A D+D G A ++Y + GND K F
Sbjct: 3261 SVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSIAEGNDAKKF 3320
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+ G + + ++D + + ++ L+V+A P + A V+IE+ D+NDN P
Sbjct: 3321 KIVEETGVIKVSGDIDRE-----EVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSP 3375
Query: 305 EF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
EF + + +LPN +V+ + D+D NG
Sbjct: 3376 EFSSTNLTTVLSESSLPNA-AVIHLRPHDRDALGNG 3410
Score = 61.7 bits (143), Expect = 2e-07
Identities = 51/156 (32%), Positives = 76/156 (48%), Gaps = 12/156 (7%)
Query: 976 IPPSKLSADALEV--KRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNI 1029
I KL+ + +E + F I+ G + A+ L E ++ I D GN L+
Sbjct: 1759 ISGDKLTYEIVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNPRLSAFA 1818
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
V++ V D+ND PVF + Y+ V Y + V ATD D ANLT+ + DT
Sbjct: 1819 DVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGD--SAANLTFSLARQDT 1876
Query: 1090 DLPFEISPLTGVLSV-NGELDRETEDKYILTVVARD 1124
+L F ++PLTGV++V N L R D Y + + D
Sbjct: 1877 EL-FAVNPLTGVVTVSNAALLR--RDTYTIKLTVSD 1909
Score = 60.9 bits (141), Expect = 3e-07
Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 10/147 (6%)
Query: 222 DQDLGVGATLRYELIS---GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
D D GV + Y ++ LF ++S +G + K LD + +Q + VL ++A
Sbjct: 1439 DPDAGVNGEVEYCIVQTAKAESASLFKIESHSGRILTVKPLDYET---MQEH--VLTIKA 1493
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S P + V + + D+ND+ PEF + + + G ++L+V+ATDKD G N
Sbjct: 1494 SDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATDKDDGTN 1553
Query: 339 GEFTYQL--DDPKGAFSIDPRSGWLTV 363
+ Y + + + S+D SG + V
Sbjct: 1554 SKLKYSIVSGNTNKSLSVDQNSGVVKV 1580
Score = 60.5 bits (140), Expect = 3e-07
Identities = 43/152 (28%), Positives = 73/152 (48%), Gaps = 4/152 (2%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA-NTFVLQVQASQLNNPLKTAQARVE 293
+ISGN++ +FS+DS S F ++ N ++ ++ L V + +V
Sbjct: 33 IISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRTKRTLDRTKVN 92
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFS 353
I + D NDN P F Y +I E++P S+ ++ A D D G NG Y + +F+
Sbjct: 93 ITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTSFA 152
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
I+P SG ++V + H R+ V A++
Sbjct: 153 INPISGVVSVAQKLSNSARIH---RLTVVARD 181
Score = 59.7 bits (138), Expect = 6e-07
Identities = 52/187 (27%), Positives = 83/187 (44%), Gaps = 12/187 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE PIGT + DL G+ + +F S D+ +V + ++ +
Sbjct: 5 IPEITPIGTPV----KCDLKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTS 60
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ S+ + + LN+ D D V + V D ND+ P+F K Y + E
Sbjct: 61 KRLNRESV---ASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPED 117
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ +++A DAD G N + Y + T F I+P++GV+SV +L +
Sbjct: 118 IPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS--FAINPISGVVSVAQKLSNSAR-IHR 174
Query: 1118 LTVVARD 1124
LTVVARD
Sbjct: 175 LTVVARD 181
Score = 59.3 bits (137), Expect = 8e-07
Identities = 76/317 (23%), Positives = 126/317 (39%), Gaps = 24/317 (7%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAPIGPSLTIPLTVPRG-- 137
+ V + I D+ND P F + Y+ + E P+G + P + T+ +G
Sbjct: 1088 IPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGGSLLRYTITKGNE 1147
Query: 138 ---LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
I +P Y + VS +D G + + + + D
Sbjct: 1148 QNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQPE 1207
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
KE Q V+ ++ + + A D+D+G A LRY + GN F +DS +G +
Sbjct: 1208 FKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSITKGNRDNKFIIDSRSGEI 1267
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN---DNLPEFEVDF 310
F L +D E ++ L + A P + V I+++ N N P F
Sbjct: 1268 FTNVSL-VDGE------SYDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQ 1320
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
Y+ I E+ VL + A D D + TY + + F+ID G++TV +
Sbjct: 1321 YSADIQEDKRINSFVLIIGAEDPD---FDQITYNIASGNHGNKFTIDRYGGFITVAHS-- 1375
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE S ++V A +
Sbjct: 1376 LDREEKSFYSLRVEATD 1392
Score = 58.8 bits (136), Expect = 1e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Query: 209 HKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQ 268
+ E F + A D D G A L Y + S + + F +D+ +G L+ L D E++ Q
Sbjct: 2457 YPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSGMLY--SRLMFDRENSSQ 2514
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
A ++ V + + VE+ L+D NDN P FE+ Y+ +I ++ G VL
Sbjct: 2515 A---IMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMT 2571
Query: 329 MATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
A+D D N TY + F+I+ +G + V +
Sbjct: 2572 SASDPDASSNAALTYVIVGHQTPPVFTINAATGVIQVSRE 2611
Score = 58.0 bits (134), Expect = 2e-06
Identities = 91/344 (26%), Positives = 146/344 (42%), Gaps = 66/344 (19%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGL 138
A +V V + D NDN P+F+++PY F++ +G V +G
Sbjct: 2017 AQAAVHVQVIDRNDNQPVFINSPY----------------FIVLQLG--------VAQG- 2051
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY-------- 190
TI +A D D + N+++ Y ++ G D G+F++ V++ R + D
Sbjct: 2052 TIIGQAQATDADIGS--NANLRYDLIGG-DPGYFSISRKTGEVVVRRTLDDVKVPRLFTL 2108
Query: 191 --DAGDKEFQLVIMASGKRIHKEI-LFPE----PIHAIDQDLGV-----------GATLR 232
+A D F+ + K + KE +F + + A D +G GA +
Sbjct: 2109 MVEATDGLFRTEAVVKIKVVDKETPVFDQLSFSKVLAEDTPIGSEVTSVTARSPNGAGIL 2168
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y + G+ FS+D G + L LD + + L V+A+ + A V
Sbjct: 2169 YSITGGDPVNQFSIDFKTGVVTLVSSLDYETR-----TKYKLVVRATDARTSSHSDVA-V 2222
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK--G 350
++ + D+ND P F Y +I E+ P +V+ V A D D G N E Y + + G
Sbjct: 2223 DVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVG 2282
Query: 351 A-FSIDPRSGWLTVRNQTVLDREAHSSLRM-KVYAKETNPSVVG 392
A F ID +SG + V LD E+ M V A E PS+ G
Sbjct: 2283 AFFKIDKKSGVVFVAKS--LDYESRVVHEMIIVAADEGKPSLTG 2324
Score = 54.0 bits (124), Expect = 3e-05
Identities = 89/358 (24%), Positives = 142/358 (39%), Gaps = 42/358 (11%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V V D ND+ PVF + Y ++ ++G+ ATDAD G NANL Y + D
Sbjct: 2020 AVHVQVIDRNDNQPVFINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDP 2079
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F IS TG + V LD + +V +G V+ +P
Sbjct: 2080 GY-FSISRKTGEVVVRRTLDDVKVPRLFTLMVEATDGLFRTEAVVKIKV-----VDKETP 2133
Query: 1150 KF--YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI 1207
F +F ++L P E+++ S + +I P+ +
Sbjct: 2134 VFDQLSFSKVLAEDTPIGSEVTSVTARSPNGAGIL-YSITGGDPVNQFSIDFKTGVVTLV 2192
Query: 1208 G--NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+ Y L R S S + VTV DV D P F Y
Sbjct: 2193 SSLDYETRTKYKLVVRATDAR---TSSHSDVAVDVTVTDVNDVA-----PAFNRSLYLAT 2244
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
I E+ +V++ + N ++ Y+I +N + + F ID ++G +++ +S D
Sbjct: 2245 ISESTPVDTAVVTVKAIDGDSGINKEINYFI--QNVSRVGAFFKIDKKSGVVFVAKSLDY 2302
Query: 1324 EVKDTYE-VIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
E + +E +IV A+ K S L G T+ V+VV + D NDN+P+F
Sbjct: 2303 ESRVVHEMIIVAADEGKPS--------------LTGETR--VRVV--LMDANDNAPRF 2342
Score = 53.6 bits (123), Expect = 4e-05
Identities = 68/278 (24%), Positives = 111/278 (39%), Gaps = 18/278 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +S ++ TV I D NDN P F + Y V V T + ++ + +
Sbjct: 1184 GTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNA 1243
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGND-DGHFALESSHKPVLLLRK--VLD 189
+ +T F D + + S+V G D E + P L ++D
Sbjct: 1244 DLRYSITKGNRDNKFIIDS-RSGEIFTNVSLVDGESYDLTIVAEDNGLPKLSTSTNVLID 1302
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGAT----LRYELISGNDRKLFS 245
G+K + + K+ +I + I++ +G + Y + SGN F+
Sbjct: 1303 VIQGNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFDQITYNIASGNHGNKFT 1362
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+D G + + LD + + + + L+V+A+ N TA V I +LD+NDN P+
Sbjct: 1363 IDRYGGFITVAHSLDRE-----EKSFYSLRVEATDGYN---TASVPVTINILDVNDNSPQ 1414
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
Y + EN G V V D D G NGE Y
Sbjct: 1415 PARREYRAHVAENSDVGTLVTTV--KDPDAGVNGEVEY 1450
Score = 53.6 bits (123), Expect = 4e-05
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 26/220 (11%)
Query: 936 PLFLIPE-NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
P F++ + + GT I + A D D G N +RY+ + D YF I
Sbjct: 2039 PYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDL----------IGGDP----GYFSI 2084
Query: 995 NERHGHVIVARSLPPESE---FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ + G V+V R+L F L + A DG + + V +K V+ PVF + +
Sbjct: 2085 SRKTGEVVVRRTLDDVKVPRLFTLMVEATDGLFRTEAV---VKIKVVDKETPVFDQL--S 2139
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
F+ A+ T + +V + A A + Y I D F I TGV+++ LD E
Sbjct: 2140 FSKVLAEDTP-IGSEVTSVTARSPNGAGILYSITGGDPVNQFSIDFKTGVVTLVSSLDYE 2198
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
T KY L V A D DVND +P F
Sbjct: 2199 TRTKYKLVVRATD--ARTSSHSDVAVDVTVTDVNDVAPAF 2236
Score = 52.4 bits (120), Expect = 9e-05
Identities = 112/435 (25%), Positives = 167/435 (38%), Gaps = 67/435 (15%)
Query: 992 FVINERHGHVIVARS-LPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWY 1050
F +N G V V+ + L + + ++ DG N + VR+ +++ F + Y
Sbjct: 1879 FAVNPLTGVVTVSNAALLRRDTYTIKLTVSDG-NHTAHARVRIRCENLPSSDLQFSRKNY 1937
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG--EL 1108
+ +V E L V A G T I PS+ F I P TGV+S+ +L
Sbjct: 1938 SASVREGVSVDSELVTVRALGYPIGSTITYT-IINPSEL---FHIVPSTGVMSIRAGFDL 1993
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
DRE+ D Y + V ARD+ D NDN P F
Sbjct: 1994 DRESIDAYQVIVQARDD-SVPPNVAQAAVHVQVIDRNDNQPVFI---------------- 2036
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT---DFIGNGNGLILYS-----LPQ 1220
N + V+ + V + TI A T A + +N D IG G S +
Sbjct: 2037 -NSPYFIVLQLGVAQGTIIGQAQ--ATDADIGSNANLRYDLIGGDPGYFSISRKTGEVVV 2093
Query: 1221 RKNQQNLGLPSL-----SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
R+ ++ +P L +T L T A V +V + PVF + + E+ E
Sbjct: 2094 RRTLDDVKVPRLFTLMVEATDGLFRTEAVVKIKVVDKETPVFDQLSFSKVLAEDTPIGSE 2153
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ S +T N Y + D F ID + G + LV S D E + Y+++VRA
Sbjct: 2154 VTS--VTARSPNGAGILYSITGGDP--VNQFSIDFKTGVVTLVSSLDYETRTKYKLVVRA 2209
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA-IPTT 1394
+ S + DV V V + DVND +P F NR L A I +
Sbjct: 2210 TDARTS------------------SHSDVAVDVTVTDVNDVAPAF---NRSLYLATISES 2248
Query: 1395 APFGYQVMQLKGAIG 1409
P V+ +K G
Sbjct: 2249 TPVDTAVVTVKAIDG 2263
Score = 49.2 bits (112), Expect = 9e-04
Identities = 69/288 (23%), Positives = 119/288 (41%), Gaps = 44/288 (15%)
Query: 144 IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-----------KVLDYDA 192
+R DK + NS + YSIVSGN + +++ + V + KV D
Sbjct: 1541 LRVIATDKDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLVHQYALKVQSTDG 1600
Query: 193 GDKEF--QLVIMASGKRIHKEILFPEPIHAI--------DQDLGV----GATLRYELISG 238
G+ Q+ + + I K F +P + + DQ + G YE++ G
Sbjct: 1601 GEPPLKTQVDVKVKVRGIVKNFAFEKPKYEVSLPENSPPDQAIATVVYNGILPVYEIVPG 1660
Query: 239 NDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+ F++ +G + +K D + + + L+++A+ + + V I+
Sbjct: 1661 RSPCWRDFTVQRQSGVIISKKSFDAEEVTHCK-----LEIRANSTDGQHSSTLVIVTIQ- 1714
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVL-----QVMATDKDQGENGE-FTYQL--DDP 348
D NDN P FE + E P G +VL Q++A DQ +G+ TY++
Sbjct: 1715 -DKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDISGDKLTYEIVETSA 1773
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
+ FSI P +G +T VLD E K+ ++ + FAD
Sbjct: 1774 RDVFSIHPATGAITTAK--VLDYEVTPQYAFKIKVTDSGNPRLSAFAD 1819
Score = 49.2 bits (112), Expect = 9e-04
Identities = 49/193 (25%), Positives = 89/193 (46%), Gaps = 23/193 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +GT ++++ A D DSG N QI+Y A+ + K++ ++ E G
Sbjct: 3281 VDENSALGTFVLQVFATDRDSGTNAQIKYSI------------AEGNDAKKFKIVEET-G 3327
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ V+ + E + +RL + A D G + D + V + V DVND+ P F T +
Sbjct: 3328 VIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTV-VDIEVTDVNDNSPEFSSTNLTTVL 3386
Query: 1055 EEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E+ + + D D G A + + D F++ G+++ G++ ++
Sbjct: 3387 SESSLPNAAVIHLRPHDRDALGNGAPYQFTLISGDAS-RFKLHS-NGLITKIGDVS-HSD 3443
Query: 1114 DKYILTVVARDNG 1126
+Y L V+ DNG
Sbjct: 3444 GQYRLRVLVADNG 3456
Score = 48.0 bits (109), Expect = 0.002
Identities = 41/151 (27%), Positives = 73/151 (48%), Gaps = 11/151 (7%)
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
L+ +T+ +++ S N+ TA ARV I +NLP ++ F + ++ G SV
Sbjct: 1896 LRRDTYTIKLTVSDGNH---TAHARVRIRC----ENLPSSDLQFSRKNYSASVREGVSVD 1948
Query: 327 QVMATDKDQGE--NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+ T + G TY + +P F I P +G +++R LDRE+ + ++ V A+
Sbjct: 1949 SELVTVRALGYPIGSTITYTIINPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQAR 2008
Query: 385 ETN--PSVVGTFADSQRIAKWRRQPLETNAP 413
+ + P+V Q I + QP+ N+P
Sbjct: 2009 DDSVPPNVAQAAVHVQVIDRNDNQPVFINSP 2039
Score = 45.2 bits (102), Expect = 0.014
Identities = 83/361 (22%), Positives = 136/361 (37%), Gaps = 34/361 (9%)
Query: 990 RYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
R F + + G +I +S E + +L I A + + V V ++D ND+ P+F+
Sbjct: 1666 RDFTVQRQSGVIISKKSFDAEEVTHCKLEIRANSTDGQHSSTLVIVTIQDKNDNQPIFEH 1725
Query: 1048 TWYNFNVEEA--QYTRRVLGKVD-----ATDADFGQNANLTYFIQPSDTDLPFEISPLTG 1100
+V E Q T + K ATD D + LTY I + F I P TG
Sbjct: 1726 ARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDISGD-KLTYEIVETSARDVFSIHPATG 1784
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
++ LD E +Y + D+G D+ND +P F A
Sbjct: 1785 AITTAKVLDYEVTPQYAFKIKVTDSG-NPRLSAFADVKIHVTDINDIAPVFSAS------ 1837
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENA--PIGTTVAKVFAND--TDFIGNGNGLILY 1216
+ L ++ V M+ N + ++FA + T + N +L
Sbjct: 1838 TYHATVYLPSYAGTRVTMVTATDGDSAANLTFSLARQDTELFAVNPLTGVVTVSNAALL- 1896
Query: 1217 SLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
R++ + L V + + SD F + Y + E V+ EL
Sbjct: 1897 ----RRDTYTIKLTVSDGNHTAHARVRIRCENLPSSDLQ-FSRKNYSASVREGVSVDSEL 1951
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR--SPDREVKDTYEVIVR 1334
V++ + + Y I+N ++ F I P G + + DRE D Y+VIV+
Sbjct: 1952 VTVRALGYPIGSTITYTIINPSE-----LFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQ 2006
Query: 1335 A 1335
A
Sbjct: 2007 A 2007
Score = 37.1 bits (82), Expect = 3.7
Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 13/157 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V++EVT D NDN+P F +NL +S+ VI ++ D D NG Q T
Sbjct: 3363 VDIEVT--DVNDNSPEFSSTNLTTVLSESSLPNAAVI-HLRPHDRDALGNGA---PYQFT 3416
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S FK++ N + + +G++ L V +D P S+ V E
Sbjct: 3417 LISGDASRFKLHSNGLITKIGDVSHSDGQYRLRVLVADNGHPPQSTEVSITVKIAE---- 3472
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
+K + P++ Y GSN+ G +G+++ D
Sbjct: 3473 SKTHPPNVHPL--TVYVNLYGSNLN-GGVIGRVKATD 3506
Score = 35.9 bits (79), Expect = 8.6
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAG 1484
A D D G N +RY + N + F I+P +G +R L RD G
Sbjct: 450 AEDLDSGGNGKVRYSLANLRPVPFEIEPDTGIIRTTTNLDRDTG 493
>UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor;
n=115; Euteleostomi|Rep: Protocadherin-11 X-linked
precursor - Homo sapiens (Human)
Length = 1347
Score = 138 bits (333), Expect = 1e-30
Identities = 140/517 (27%), Positives = 223/517 (43%), Gaps = 36/517 (6%)
Query: 415 EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK 474
EK TYV KV E+ + + + V VT D NDN+PVF + + E S+ NA
Sbjct: 211 EKDTYVMKVKV----EDGGFPQRSSTAILQVSVT--DTNDNHPVFKETEI-EVSIPENAP 263
Query: 475 VGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRH 532
VGT + ++ A D D+G+N + + + F +N TG +++ E E H
Sbjct: 264 VGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNH 323
Query: 533 ALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP-DFMGAPYEFWV--GSNVGIG 589
L V ASD P+ A+V + VT N P I ++ P V N+ +
Sbjct: 324 KLLVLASDGGLMPAR-----AMVLVNVT-DVNDNVPSIDIRYIVNPVNDTVVLSENIPLN 377
Query: 590 TSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN-RPMYDFEAV 648
T + I V D ++ +E +PF + +++ + + ++
Sbjct: 378 TKIALITVTDKDADHNGRVTCFTDHE--IPFRLRPVFSNQFLLETAAYLDYESTKEYAIK 435
Query: 649 ALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSI 708
L +A + + + + V DE S + + EN++ I T +S++
Sbjct: 436 LLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG----IQLTKVSAM 491
Query: 709 YGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
+ N + D + ++ G + K LDREK D Y T++A+ N GV
Sbjct: 492 DADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDN-GVPPL 550
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMEN-SKIGTEIKMDNIIKATDADEGTNALFM 826
V + I D+NDN PVF H Y ++ EN + GT +I TD D G N+
Sbjct: 551 TSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTV----GLITVTDPDYGDNSAVT 606
Query: 827 YTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIG 884
++ E + F +D TGV++ S DREK+ Y + A D G + SS A++ I +
Sbjct: 607 LSILDENDD-FTIDSQTGVIR-PNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 664
Query: 885 DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
D NDNKP F N + + GT F +I V
Sbjct: 665 DVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
Score = 113 bits (273), Expect = 3e-23
Identities = 116/473 (24%), Positives = 203/473 (42%), Gaps = 23/473 (4%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+++ V + + D NDN P+F P+ + S+ N+ + + AVDPD+G NG+
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLF-PATVINISIPENSAINSKYTLPAAVDPDVGINGVQN 175
Query: 497 YDLQRTSNLTITSPFKINPNTGTVS--VAESPILEGRHALFVEASDQPANPSERRYSLAV 554
Y+L ++ N+ + P + + + + +V +R S A+
Sbjct: 176 YELIKSQNIFGLDVIE-TPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAI 234
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN---DVSYDL 610
+ + VT T N P F E + N +GTSV Q+ DA +N S+
Sbjct: 235 LQVSVT-DTNDNH---PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSN 290
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
L F + +G+IT+ + L R P + +A + + V+V DVN
Sbjct: 291 LVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLA-SDGGLMPARAMVLVNVTDVN 349
Query: 671 DE-RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D + ++ +P+ V + +I ++ + G V ++
Sbjct: 350 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVI-AEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ + T LD E Y + ++ A+ K ++ + + + I ++DENDN PVF
Sbjct: 410 PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAM--LFIKVKDENDNAPVFT 467
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ I EN+ G ++ + A DAD G NA Y L + F +D TG++
Sbjct: 468 QSFVTVSIPENNSPGIQLTK---VSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTV 524
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ LDREK+ Y +++A+D G L+S + + I D+NDN P F E N
Sbjct: 525 V-KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYN 576
Score = 97.9 bits (233), Expect = 2e-18
Identities = 81/246 (32%), Positives = 108/246 (43%), Gaps = 22/246 (8%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
LN +A I+VK +N A Q IPEN G + K++A+D DSG N +I Y
Sbjct: 446 LNQSA-MLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYL 504
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NL 1025
+ PP F ++ R G + V + L E E + I A D G L
Sbjct: 505 LGPDA--PPE------------FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPL 550
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
N++V V + D ND+ PVF YNF V E +G + TD D+G N+ +T I
Sbjct: 551 TSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL 610
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ D F I TGV+ N DRE ++ Y V A D G DVN
Sbjct: 611 DENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVN 667
Query: 1146 DNSPKF 1151
DN P F
Sbjct: 668 DNKPVF 673
Score = 77.8 bits (183), Expect = 2e-12
Identities = 157/658 (23%), Positives = 255/658 (38%), Gaps = 104/658 (15%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+ ++ IED NDN P+F I ENS I ++ + A D D G N + Y L
Sbjct: 122 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLP---AAVDPDVGINGVQNYEL 178
Query: 830 FGE----GKEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIM 882
G ++ + E + + I LDRE+K Y + + D G SS A L +
Sbjct: 179 IKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVS 238
Query: 883 IGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPE 942
+ D NDN P F + E I N G ++ ++ A D D I E
Sbjct: 239 VTDTNDNHPVFKETE------IEVSIPENAPVGTSVTQL-----HATDAD-------IGE 280
Query: 943 NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY-FVINERHGHV 1001
N I + +L S + ++ + N+ + K D E + ++ G +
Sbjct: 281 NAK-----IHFSFSNLVSNIARRL-FHLNATTGLITIKEPLDREETPNHKLLVLASDGGL 334
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
+ AR++ + ++ D + +I +R V VND + + N T+
Sbjct: 335 MPARAM-------VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLN--------TK 379
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDKYIL 1118
L V DAD N +T F +D ++PF + P+ +L LD E+ +Y +
Sbjct: 380 IALITVTDKDAD--HNGRVTCF---TDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAI 434
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
++A D G D NDN+P F + PE + + M
Sbjct: 435 KLLAADAG-KPPLNQSAMLFIKVKDENDNAPVF--TQSFVTVSIPENNSPGIQLTKVSAM 491
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL--------GLP 1230
+ N +G F+ D G ++ L + K + L G+P
Sbjct: 492 DADSGPNAKINYLLGPDAPPEFSLD---CRTGMLTVVKKLDREKEDKYLFTILAKDNGVP 548
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENF 1288
L+S + V++ D D + PVF Y + EN+ + V L+++ ++ +N
Sbjct: 549 PLTSNVTVFVSIIDQND-----NSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
+ IL+END F ID + G + S DRE +++Y V+
Sbjct: 604 AVTLSILDEND-----DFTIDSQTGVIRPNISFDREKQESYTFYVK-------------- 644
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF--TNGNRPLVTAIPTTAPFGYQVMQL 1404
AED KV + + DVNDN P F N +P+T P G V Q+
Sbjct: 645 ---AEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQV 698
Score = 77.4 bits (182), Expect = 3e-12
Identities = 52/168 (30%), Positives = 80/168 (47%), Gaps = 8/168 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D G A + Y L+ + FSLD G L + K+LD + E + ++ +
Sbjct: 488 VSAMDADSGPNAKINY-LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-----DKYLFTIL 541
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P T+ V + ++D NDN P F + YN + ENLP +V + TD D G+
Sbjct: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N T + D F+ID ++G +R DRE S V A++
Sbjct: 602 NSAVTLSILDENDDFTIDSQTG--VIRPNISFDREKQESYTFYVKAED 647
Score = 76.2 bits (179), Expect = 7e-12
Identities = 52/178 (29%), Positives = 91/178 (51%), Gaps = 21/178 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNG-------SLFLEKELDLDAEHNLQANTF 272
A+D D+G+ YELI + +F LD + L ++KELD + + +T+
Sbjct: 163 AVDPDVGINGVQNYELIKSQN--IFGLDVIETPEGDKMPQLIVQKELDRE-----EKDTY 215
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V++V+ P +++ A +++ + D NDN P F+ +SI EN P G SV Q+ ATD
Sbjct: 216 VMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD 275
Query: 333 KDQGENGEFTYQLDD-----PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D GEN + + + + F ++ +G +T++ LDRE + ++ V A +
Sbjct: 276 ADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP--LDREETPNHKLLVLASD 331
Score = 67.7 bits (158), Expect = 2e-09
Identities = 82/341 (24%), Positives = 143/341 (41%), Gaps = 47/341 (13%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTV 134
++I + + IED+NDN P+F T ++++ E + K L A + P + I
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSK--YTLPAAVDPDVGI--NG 172
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-KVLDYDAG 193
+ + K F D TP D ++ + L+ K +++ KV D
Sbjct: 173 VQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE-----LDREEKDTYVMKVKVEDGGFP 227
Query: 194 DKEFQLVIMASG----------KRIHKEILFPE---------PIHAIDQDLGVGATLRYE 234
+ ++ S K E+ PE +HA D D+G A + +
Sbjct: 228 QRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFS 287
Query: 235 ---LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
L+S R+LF L++ G + +++ LD + N + L V AS + L A+A
Sbjct: 288 FSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHK-----LLVLAS--DGGLMPARAM 340
Query: 292 VEIELLDLNDNLPEFEVDFY----NISIV--ENLPNGFSVLQVMATDKDQGENGEFTYQL 345
V + + D+NDN+P ++ + N ++V EN+P + + TDKD NG T
Sbjct: 341 VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTC-F 399
Query: 346 DDPKGAFSIDP-RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D + F + P S + LD E+ +K+ A +
Sbjct: 400 TDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAAD 440
Score = 64.1 bits (149), Expect = 3e-08
Identities = 44/137 (32%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+ LE LD E + + +++ A+ P A + I++ D NDN P F
Sbjct: 413 SNQFLLETAAYLDYESTKE---YAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 469
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTV 368
F +SI EN G + +V A D D G N + Y L D FS+D R+G LTV +
Sbjct: 470 FVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKK-- 527
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE + AK+
Sbjct: 528 LDREKEDKYLFTILAKD 544
Score = 63.3 bits (147), Expect = 5e-08
Identities = 103/485 (21%), Positives = 185/485 (38%), Gaps = 50/485 (10%)
Query: 940 IPENIPIGTTIIKLN-ALDLDSGLNGQIRYEFNSEVY-IPPSKLSADALEVKRYFVINER 997
+PEN+ IG + LN +L + L ++++ + +P ++ D E+ F R
Sbjct: 34 MPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEI---FTTGAR 90
Query: 998 HGHVIVARSLPPESEFRLNIS-ALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ +P + + A+ + + +R ++D+ND+ P+F T N ++ E
Sbjct: 91 IDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPE 150
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-----SPLTGVLSVNGELDRE 1111
A D D G N Y + S ++ L V ELDRE
Sbjct: 151 NSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDRE 210
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+D Y++ V D G D NDN P F + +E PE +
Sbjct: 211 EKDTYVMKVKVEDGG-FPQRSSTAILQVSVTDTNDNHPVFKETE--IEVSIPENAPVGT- 266
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN---GLILYSLP----QRKNQ 1224
SV + A I ENA I + + + +N + + N GLI P + N
Sbjct: 267 ---SVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNH 323
Query: 1225 QNLGLPS----LSSTAILMVTVADVPDEVEMSDKPVFISRYYE-LEIEENVNAPVELVSL 1279
+ L L S + + A+++V V DV D V D ++ + + + EN+ ++ +
Sbjct: 324 KLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALI 383
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+T+ + R +++ R R V ++ A
Sbjct: 384 TVTDKDADHNGRVTCFTDHEIPFRL------------------RPVFSNQFLLETAAYLD 425
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGY 1399
Y + I +A D + + +++KD NDN+P FT + +IP G
Sbjct: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSF--VTVSIPENNSPGI 483
Query: 1400 QVMQL 1404
Q+ ++
Sbjct: 484 QLTKV 488
Score = 58.4 bits (135), Expect = 1e-06
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 13/166 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I D D G + + ++ ND F++DS G + + D E + ++ V+
Sbjct: 592 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTG--VIRPNISFDRE---KQESYTFYVK 644
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN---GFSVLQVMATDKD 334
A +++ A+V I ++D+NDN P F V N S LP+ G V QV+A D D
Sbjct: 645 AEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDND 704
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ-TVLDREAHSSL 377
G N E Y + + + F+ID +G +T+ + V D H L
Sbjct: 705 TGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 750
Score = 52.8 bits (121), Expect = 7e-05
Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 11/124 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFV--PSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
S V + ++D NDN PVF+ PSN YE + S GTV+ +V AVD D G N V Y
Sbjct: 655 SSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPST-NPGTVVFQVIAVDNDTGMNAEVRY 713
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVV 555
+ + + F I+ TG +++ E + G H + V+A+D + +S+ +V
Sbjct: 714 SIVGGNTRDL---FAIDQETGNITLMEKCDVTDLGLHRVLVKAND--LGQPDSLFSVVIV 768
Query: 556 TIEV 559
+ V
Sbjct: 769 NLFV 772
Score = 52.0 bits (119), Expect = 1e-04
Identities = 51/206 (24%), Positives = 93/206 (45%), Gaps = 27/206 (13%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPT-GEKAFIFLIAP-IGPSLTI 130
G+ +++ ++V V I D NDN P+F Y+ V E P G I + P G + +
Sbjct: 546 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV 605
Query: 131 PL---------TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
L T+ + + +FDR+K + + V D G + SS K
Sbjct: 606 TLSILDENDDFTIDSQTGVIRPNISFDREKQES-----YTFYVKAEDGGRVSRSSSAKVT 660
Query: 182 LLLRKVLD------YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL 235
+ + V D + ++LV+ ++ ++F + A+D D G+ A +RY +
Sbjct: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGT---VVFQ--VIAVDNDTGMNAEVRYSI 715
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDL 261
+ GN R LF++D G++ L ++ D+
Sbjct: 716 VGGNTRDLFAIDQETGNITLMEKCDV 741
Score = 37.1 bits (82), Expect = 3.7
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS--LTIPLTVPRGLT 139
S T Y++ D + + VT++ + K +F++ P S L +P T P G
Sbjct: 638 SYTFYVK-AEDGGRVSRSSSAKVTINVVDVNDNKP-VFIVPPSNCSYELVLPSTNP-GTV 694
Query: 140 IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
+F+ I A D D N++V YSIV GN FA++ + L+ K D G
Sbjct: 695 VFQVI-AVDND--TGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLG 745
>UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 3342
Score = 137 bits (331), Expect = 3e-30
Identities = 189/710 (26%), Positives = 285/710 (40%), Gaps = 77/710 (10%)
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL---LDLNDNLPE 305
+ S+++ +DLD+ N V S N + +A EI L + ND L
Sbjct: 942 IGSSIYVATAMDLDSGDN----GLVRYRLTSNPGNTFRIVEATGEIILNKEVSYNDQL-S 996
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
FEVD E G L V+ D + +NG P P S +
Sbjct: 997 FEVDIQAYDAGEPSLEGSLTLTVIILDVN--DNGPVFTMGFYPVSILENLPISTPVVQVE 1054
Query: 366 QTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIA-KWRRQPLETNAPLEKTTYVFPDK 424
T DR A++ + + +P FA R + RQ L+ T +
Sbjct: 1055 ATDNDRGANALITYTLTPNNDSPY----FAVFPREGWLYTRQVLDRELKSTFTLTIMASD 1110
Query: 425 VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKA 484
G+ +N S V+VT++DANDN P F + Y F + N GT + +V+A
Sbjct: 1111 SGSPPQN---------SSATVQVTVVDANDNAPHFTKKS-YHFHINENLPAGTEVDRVEA 1160
Query: 485 VDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQP 542
VDPDLG NG V Y L + + TI G + E ++ L + A D
Sbjct: 1161 VDPDLGPNGQVTYTLSPSGDFTIDEE-------GVIRTTHPLDREAAYSYRLIIRAVDG- 1212
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
NP+ S A V I V N P Y+ V G V I D
Sbjct: 1213 GNPALS--SSATVYINVN-DLNDNAPVFSQ--DRTYQASVREEQPAGEFVAWIIATDTDS 1267
Query: 603 Q--NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT 660
++SY L+ + P + + SGVI+ + R + Y +A Q+ N +
Sbjct: 1268 GVLGNISYSLI----DSSPKFIIDSSGVISTAAAIDREDESYYTLTVLA-QDGGNPPMQA 1322
Query: 661 NATVHV--VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
A+V V +D+ND + A S IF EN + + + + NG
Sbjct: 1323 TASVRVRILDLNDNVPI---AAMSAYIFTADENIQPPTVVGVVSASDMDVGDNGKIYYYI 1379
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
N DV D G ++ + +D E Y +T+IA+ N + + VTI I
Sbjct: 1380 TEGNDFDVWD--VNHSSGEVYNVRVVDYEMAAHYTLTIIAQDNNVPQTHSTSISVTINIL 1437
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
D+NDN P F+ + EN I + + ATDAD G N L YT+ E ++ F
Sbjct: 1438 DQNDNTPDFDQDLIYLTLQENVGINHVLWT---VSATDADSGANGLIRYTILTE-QDFFA 1493
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEF 893
VDE TG ++ I ++D E ++ L + A+D + ++ + + + I D NDN P F
Sbjct: 1494 VDEYTGTLRTI-QNVDHEINHVFLLVIQAQDQAINVSARRAATSTVEVRIYDSNDNNPVF 1552
Query: 894 -----NQIEENSKVR---IH-----RETKLNGTAGFTIIEVKPKNKFALD 930
+ E+ V IH ++ NG G+TI KF+LD
Sbjct: 1553 VSRSSTDVMEDEPVGFNVIHIIATDEDSGENGRVGYTITSGNEDGKFSLD 1602
Score = 125 bits (301), Expect = 1e-26
Identities = 132/468 (28%), Positives = 201/468 (42%), Gaps = 36/468 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VEV + D+NDNNPVFV + + + + VG + + A D D G+NG V Y + +
Sbjct: 1538 VEVRIYDSNDNNPVFVSRSSTD--VMEDEPVGFNVIHIIATDEDSGENGRVGYTITSGNE 1595
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F ++ TG +++A S E + + L + A+D +L + I+V
Sbjct: 1596 ---DGKFSLDAVTGLLTIAHSLDHEHKRDYELVILATDHGTVQRMATQTLTIRVIDVN-- 1650
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPF 620
++P P F + Y V + GT VG + D+ ++Y+L G+ F
Sbjct: 1651 ---DQP--PRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPEEIARGM-F 1704
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDVNDERGVLLK 678
+ +G I L R R Y A+ A + T V+V+DVND
Sbjct: 1705 RINATTGEIRTKAILDREQRDSYVVTVYAMDGAFPARYDMAT-VLVYVMDVNDNNPTF-- 1761
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GT 737
A + EN + I T+ G++ + I D + +I + G
Sbjct: 1762 -APPTFDITLPENQSPGVIHNAIATDADE---GPNGDLIYSITGG-DPKNAFSINQSTGA 1816
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
IFT LDRE Y +T+ A ++G +G + + + D NDN PVF +Y I
Sbjct: 1817 IFTVGALDREDEATYTLTITAT-DQGTSPRSGTTTIRVTVTDLNDNDPVFGSMSYYKSIP 1875
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
E++ I I + ATD DEG N YTL +F +D G + G D EK
Sbjct: 1876 ESTAINATILT---VVATDDDEGLNGDVYYTLDNTTIGLFSIDPEHGEITTTG-KFDYEK 1931
Query: 858 KIMYKLSLVARDTG--GLSSE-AELIIMIGDENDNKPEFNQIEENSKV 902
+ Y + A D+G G SE ++II I D NDN P F I + V
Sbjct: 1932 ETRYTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTIPIRANV 1979
Score = 121 bits (291), Expect = 2e-25
Identities = 171/699 (24%), Positives = 274/699 (39%), Gaps = 84/699 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ + V+V L DANDN P FV Y+ + + +V A D D G NG + Y+
Sbjct: 2163 MYGYATVQVELTDANDNAPQFVQDR-YQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYE 2221
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYSLAVVT 556
+ TS T + F I+ TG V+ A+S +E + L V A D + ++ +
Sbjct: 2222 V--TSGNT-DNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGGSPQLTGTATMRIGI 2278
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
++V N+P P V ++G+G SV + D+ ++ Y
Sbjct: 2279 VDVN----DNQPVFVQM--DPVS--VSEDLGVGLSVTTVTATDSDTNPNIQYSFTSTGNP 2330
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G FA+++ SG+IT+ L R + Y E A ++ V V D ND V
Sbjct: 2331 GGYFAIDQYSGIITLARSLDRETQDGYTLELEATDTEYTTTMTLE--VIVTDENDNAPVF 2388
Query: 677 LKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ ++ + + + N A A+ + + I N F+ ++ D I
Sbjct: 2389 RQESYQVTLPELTQPNVAVVAV----NASDKDIGLNAELTYSFVDSHPSFYIDPIT---- 2440
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G IFT + ++ + + + G + + V I I D N+ PVF Y
Sbjct: 2441 GVIFTNQVIEFNDVETTIQLYVTATDSGAPALSEFVTVRIEITDVNNQSPVFVEDIYSAS 2500
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ EN +G + + A D D K + ++ KF D+ D
Sbjct: 2501 VSENVSLGHHVIT---VVAEDMDLSPE---------NSKINYFIESGNDQGKFKIDANDG 2548
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
++ +L A DT ++IG ++ +P +N
Sbjct: 2549 SITVLERLDREATDT--------YTLIIGAVDNGEP------------------VNNATA 2582
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
+IEV+ N + D + I EN T I+ ++A D D G NG++ Y S Y
Sbjct: 2583 EVVIEVEDINDHSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGTY 2642
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRL--NISALDGGNLNDNIS--- 1030
S L F I+ G V V L E R+ + A D G N S
Sbjct: 2643 ---SDL----------FAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVL 2689
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PS 1087
V + + D N+ P F + +Y+F V E + A D D G+ LTY I+ PS
Sbjct: 2690 VTITITDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIRGLGPS 2749
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ D F I P+TG + D E+ + Y V A+D G
Sbjct: 2750 NGDDYFTIDPVTGEVFTAAVFDYESANSYRFVVQAQDTG 2788
Score = 113 bits (273), Expect = 3e-23
Identities = 130/487 (26%), Positives = 204/487 (41%), Gaps = 48/487 (9%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T +E D + + + +EV + D NDN PVF + Y+ ++ + + V A D D
Sbjct: 2358 TLELEATDTEYTTTMTLEVIVTDENDNAPVFRQES-YQVTLPELTQPNVAVVAVNASDKD 2416
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTV---SVAESPILEGRHALFVEASDQPANP 545
+G N + Y S + F I+P TG + V E +E L+V A+D A P
Sbjct: 2417 IGLNAELTY-----SFVDSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSGA-P 2470
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFE 602
+ + V IE+T + P F+ Y V NV +G V + D + E
Sbjct: 2471 ALSEF--VTVRIEITDVNNQS----PVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPE 2524
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-N 661
+ ++Y + G ++G F ++ G ITV++ L R Y A+ ++ T
Sbjct: 2525 NSKINYFIESGNDQG-KFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAE 2583
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVK------ENSAGAAIGQIFHTNMSSIYGNGTGN 715
+ V D+ND HSPI HV+ EN+ + H I NG
Sbjct: 2584 VVIEVEDIND---------HSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVE 2634
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVT 774
+ D+ ++ G + + LDRE+ + TV A ++G+ + A + VT
Sbjct: 2635 YSIISGTYSDLFAIDVVS--GAVTVRGELDREEVERVEFTVQAS-DRGMENQLASVVLVT 2691
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--- 831
I I D N+ PP F Y + EN + T + A D D G Y++ G
Sbjct: 2692 ITITDFNEFPPYFPQLFYHFLVPENMPVETYVFTAG---ALDNDAGEYGELTYSIRGLGP 2748
Query: 832 -EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNK 890
G + F +D TG V F D E Y+ + A+DTGGLS + + I ++
Sbjct: 2749 SNGDDYFTIDPVTGEV-FTAAVFDYESANSYRFVVQAQDTGGLSISIQTEVNITSVDEFP 2807
Query: 891 PEFNQIE 897
P FN E
Sbjct: 2808 PMFNDQE 2814
Score = 112 bits (270), Expect = 6e-23
Identities = 119/431 (27%), Positives = 191/431 (44%), Gaps = 57/431 (13%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ GP+F I EN+PI T ++++ A D D G N I Y + P+
Sbjct: 1022 LDVNDNGPVFTMGFYPVSILENLPISTPVVQVEATDNDRGANALITYT------LTPNND 1075
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKD 1037
S YF + R G + + L E S F L I A D G+ N + +V+V V D
Sbjct: 1076 SP-------YFAVFPREGWLYTRQVLDRELKSTFTLTIMASDSGSPPQNSSATVQVTVVD 1128
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ P F K Y+F++ E + +V+A D D G N +TY + PS F I
Sbjct: 1129 ANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTLSPSG---DFTIDE 1185
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
GV+ LDRE Y L + A D G D+NDN+P F +
Sbjct: 1186 -EGVIRTTHPLDREAAYSYRLIIRAVDGG-NPALSSSATVYINVNDLNDNAP---VFSQD 1240
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
++ +E F + ++ AT ++ +G + + FI + +G+I +
Sbjct: 1241 RTYQASVREEQPAGEFVAWII-----ATDTDSGVLGNISYSLIDSSPKFIIDSSGVISTA 1295
Query: 1218 LP-QRKNQ---------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
R+++ Q+ G P + +TA + V + D+ D V P+ Y +
Sbjct: 1296 AAIDREDESYYTLTVLAQDGGNPPMQATASVRVRILDLNDNV-----PIAAMSAYIFTAD 1350
Query: 1268 ENVNAP--VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
EN+ P V +VS + + +N K+ YYI ND D+ + ++ +G +Y VR D E+
Sbjct: 1351 ENIQPPTVVGVVSASDMDVGDNGKIYYYITEGNDFDV---WDVNHSSGEVYNVRVVDYEM 1407
Query: 1326 KDTYEVIVRAE 1336
Y + + A+
Sbjct: 1408 AAHYTLTIIAQ 1418
Score = 112 bits (270), Expect = 6e-23
Identities = 116/465 (24%), Positives = 197/465 (42%), Gaps = 33/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ + +V V +LD NDN P+ S Y F+ N + TV+G V A D D+G NG + Y
Sbjct: 1320 MQATASVRVRILDLNDNVPIAAMS-AYIFTADENIQPPTVVGVVSASDMDVGDNGKIYYY 1378
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ ++ + + V V + + + L + A D N + +S +I
Sbjct: 1379 ITEGNDFDVWDVNHSSGEVYNVRVVDYE-MAAHYTLTIIAQD---NNVPQTHS---TSIS 1431
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEE 616
VT + PDF + NVGI + + DA + + Y +L E
Sbjct: 1432 VTINILDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTIL---TE 1488
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT----VHVVDVNDE 672
FAV+E +G + + ++ ++ A + N+S AT V + D ND
Sbjct: 1489 QDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSARRAATSTVEVRIYDSNDN 1548
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V + + + ++ ++ G + I T+ S G V + I + +
Sbjct: 1549 NPVFVSRSSTDVM---EDEPVGFNVIHIIATDEDS---GENGRVGYTITSGNEDGKFSLD 1602
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G + LD E + Y + ++A + G + +TI + D ND PP FE + Y
Sbjct: 1603 AVTGLLTIAHSLDHEHKRDYELVILAT-DHGTVQRMATQTLTIRVIDVNDQPPRFEQSIY 1661
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGD 851
+ E+ GT + M + A D D G N Y L E + MF ++ TG ++
Sbjct: 1662 VMNVSESQAPGTYVGM---VVAIDGDSGVNGRITYELPEEIARGMFRINATTGEIR-TKA 1717
Query: 852 SLDREKKIMYKLSLVARDTGGLSSE---AELIIMIGDENDNKPEF 893
LDRE++ Y +++ A D G + A +++ + D NDN P F
Sbjct: 1718 ILDREQRDSYVVTVYAMD-GAFPARYDMATVLVYVMDVNDNNPTF 1761
Score = 111 bits (268), Expect = 1e-22
Identities = 132/479 (27%), Positives = 210/479 (43%), Gaps = 38/479 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + + D NDN PVF + ++ +A T + V+A D D G NG V Y +
Sbjct: 1954 VQVIIDISDVNDNAPVFKTIPI-RANVTQDASSNTFVANVEADDKDSGVNGEVNYRFTQQ 2012
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S S F I+ TG ++ + L V A D +PS + V + T G
Sbjct: 2013 S-----SSFAIDTVTGVITTKSLNPGTLFYHLEVMAFDL-GSPSLSSNGIVEVWVG-TSG 2065
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ G + ++ P E +V + S + D ND+ Y L+ G E G F +
Sbjct: 2066 SGGLQFGQQTYLVQPSEAADNGDVVLSLSAF---LPDGSSSNDIVYSLVSGNENGA-FGI 2121
Query: 623 EERSG--VITVVDDLSRYN---RPMYDFEAVALQENANLS-IVTNATVHV--VDVNDERG 674
+ ++G I VV D ++ + +P A A++ N S + ATV V D ND
Sbjct: 2122 QVQAGGSAILVVADTTKLDYETQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAP 2181
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN-GTGNVRFLIANQQDVTDDIAIA 733
++ + ++ V + I+ T +S+ + GT + + + AI
Sbjct: 2182 QFVQDRYQSRVWEVPNS-------DIYVTQVSATDADEGTNGAIYYEVTSGNTDNAFAID 2234
Query: 734 E-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + T K LD E D Y +TV+A + G G + I I D NDN PVF
Sbjct: 2235 HVTGIVTTAKSLDYEIEDSYVLTVVAR-DGGSPQLTGTATMRIGIVDVNDNQPVFVQMDP 2293
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ E+ +G + + ATD+D N + +T G F +D+ +G++ + S
Sbjct: 2294 VS-VSEDLGVGLSV---TTVTATDSDTNPNIQYSFTSTGNPGGYFAIDQYSGIIT-LARS 2348
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
LDRE + Y L L A DT ++ L +++ DENDN P F Q E+ +V + T+ N
Sbjct: 2349 LDRETQDGYTLELEATDT-EYTTTMTLEVIVTDENDNAPVFRQ--ESYQVTLPELTQPN 2404
Score = 110 bits (264), Expect = 3e-22
Identities = 127/459 (27%), Positives = 198/459 (43%), Gaps = 32/459 (6%)
Query: 444 NVEVTLLDAN-DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ +VT+ A D +P S+ Y FS++ NA ++G VKA D G + Y L T
Sbjct: 806 HAQVTITVAGPDTSPPEFESSSYAFSVQENA-AQVLVGAVKAGHIDPGITFPITYTL--T 862
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S F+IN +G + S + A FV + Q A+ Y V I V
Sbjct: 863 SG-DPNDFFRINTTSGEIFTRGSGPDHEQQA-FVLITIQAASGMPPTYDDVQVNITVI-- 918
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
++P FM + + GIG+S V D+ + V Y L G F
Sbjct: 919 --DVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRLTSN--PGNTF 974
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
+ E +G I + ++S ++ ++ + A +L TV ++DVND V G
Sbjct: 975 RIVEATGEIILNKEVSYNDQLSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMG 1034
Query: 680 AHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ P+ + EN + Q+ T+ + + + D +G +
Sbjct: 1035 FY-PV--SILENLPISTPVVQVEATDNDR---GANALITYTLTPNNDSPYFAVFPREGWL 1088
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+T++ LDRE + + +T++A + G V + + D NDN P F +Y I E
Sbjct: 1089 YTRQVLDRELKSTFTLTIMAS-DSGSPPQNSSATVQVTVVDANDNAPHFTKKSYHFHINE 1147
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
N GTE+ + ++A D D G N YTL G F +DE GV++ LDRE
Sbjct: 1148 NLPAGTEV---DRVEAVDPDLGPNGQVTYTLSPSGD--FTIDEE-GVIR-TTHPLDREAA 1200
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
Y+L + A D G LSS A + I + D NDN P F+Q
Sbjct: 1201 YSYRLIIRAVDGGNPALSSSATVYINVNDLNDNAPVFSQ 1239
Score = 109 bits (261), Expect = 8e-22
Identities = 94/333 (28%), Positives = 149/333 (44%), Gaps = 23/333 (6%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
++ +G+ + V + + DVNDNVP F+ ++ E T G ++ +
Sbjct: 898 IQAASGMPPTYDDVQVNITVIDVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSG 957
Query: 128 ----LTIPLTVPRGLTIFKDIRAFDR---DKPNTPNSDVHYSI-VSGNDDGHFALESSHK 179
+ LT G T F+ + A +K + N + + + + D G +LE S
Sbjct: 958 DNGLVRYRLTSNPGNT-FRIVEATGEIILNKEVSYNDQLSFEVDIQAYDAGEPSLEGS-- 1014
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE-PIHAIDQDLGVGATLRYELISG 238
+ L +LD + F + + I P + A D D G A + Y L
Sbjct: 1015 -LTLTVIILDVNDNGPVFTMGFYPVSILENLPISTPVVQVEATDNDRGANALITYTLTPN 1073
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
ND F++ G L+ + LD + + +TF L + AS +P + + A V++ ++D
Sbjct: 1074 NDSPYFAVFPREGWLYTRQVLDRELK-----STFTLTIMASDSGSPPQNSSATVQVTVVD 1128
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
NDN P F Y+ I ENLP G V +V A D D G NG+ TY L P G F+ID
Sbjct: 1129 ANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTL-SPSGDFTIDEEG 1187
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSV 390
+R LDREA S R+ + A + NP++
Sbjct: 1188 ---VIRTTHPLDREAAYSYRLIIRAVDGGNPAL 1217
Score = 108 bits (260), Expect = 1e-21
Identities = 122/468 (26%), Positives = 203/468 (43%), Gaps = 36/468 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL + + ++D NDN PVFV + S+ + VG + V A D D N + Y
Sbjct: 2267 QLTGTATMRIGIVDVNDNQPVFVQMD--PVSVSEDLGVGLSVTTVTATDSDTNPN--IQY 2322
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
T N F I+ +G +++A S E + +E ++ Y+ +T+
Sbjct: 2323 SFTSTGNPG--GYFAIDQYSGIITLARSLDRETQDGYTLELE-----ATDTEYT-TTMTL 2374
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
EV + P F Y+ + +V + VN + + ++ +L + + +
Sbjct: 2375 EVI--VTDENDNAPVFRQESYQVTLPELTQPNVAV--VAVNASDKDIGLNAELTYSFVDS 2430
Query: 618 VP-FAVEERSGVITVVDDLSRYN--RPMYDFEAVALQENAN-LSIVTNATVHVVDVNDER 673
P F ++ +GVI + + +N A A LS + + DVN++
Sbjct: 2431 HPSFYIDPITGVI-FTNQVIEFNDVETTIQLYVTATDSGAPALSEFVTVRIEITDVNNQS 2489
Query: 674 GVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V ++ +S V EN S G + + +M N + + I + D
Sbjct: 2490 PVFVEDIYSA---SVSENVSLGHHVITVVAEDMDLSPENS--KINYFIESGNDQGKFKID 2544
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A DG+I + LDRE D Y + + A N ++ A +V I +ED ND+ P+F+H Y
Sbjct: 2545 ANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATA-EVVIEVEDINDHSPIFDHVQY 2603
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
EG I EN+ T I + ATD D G N Y++ G ++F +D +G V G+
Sbjct: 2604 EGRIAENATASTYIL---TVHATDRDIGYNGEVEYSIISGTYSDLFAIDVVSGAVTVRGE 2660
Query: 852 SLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQI 896
LDRE+ + ++ A D G L+S + I I D N+ P F Q+
Sbjct: 2661 -LDREEVERVEFTVQASDRGMENQLASVVLVTITITDFNEFPPYFPQL 2707
Score = 107 bits (258), Expect = 2e-21
Identities = 128/468 (27%), Positives = 191/468 (40%), Gaps = 38/468 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
LMS V V L D NDN PVF N Y ++ +A +GT + V A D D + G V Y
Sbjct: 698 LMSHAFVRVILEDINDNVPVFTSLN-YRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYT 756
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESP--ILEGRHALFVEASDQPANPSERRYSLAVVT 556
+ ++N F IN TG +++ S + + L V A+D S A VT
Sbjct: 757 IDSSTN---DGTFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTSANH---AQVT 810
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
I V G P+F + Y F V N VG ++ +++ + +
Sbjct: 811 ITVA----GPDTSPPEFESSSYAFSVQENAA-QVLVGAVKAGHI--DPGITFPITYTLTS 863
Query: 617 GVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV---TNATVHVVDVN 670
G P F + SG I S + F + +Q + + + V+DVN
Sbjct: 864 GDPNDFFRINTTSGEIFTRG--SGPDHEQQAFVLITIQAASGMPPTYDDVQVNITVIDVN 921
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + I S G I+ + G VR+ + + T I
Sbjct: 922 DNVPQFMAQTARTSI----PESTGIG-SSIYVATAMDLDSGDNGLVRYRLTSNPGNTFRI 976
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
A G I K + + + + + A ++ G S G +T+ I D NDN PVF
Sbjct: 977 VEAT-GEIILNKEVSYNDQLSFEVDIQA-YDAGEPSLEGSLTLTVIILDVNDNGPVFTMG 1034
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
Y I+EN I T + ++ATD D G NAL YTL F V G + +
Sbjct: 1035 FYPVSILENLPISTPVVQ---VEATDNDRGANALITYTLTPNNDSPYFAVFPREGWL-YT 1090
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
LDRE K + L+++A D+G +S A + + + D NDN P F +
Sbjct: 1091 RQVLDRELKSTFTLTIMASDSGSPPQNSSATVQVTVVDANDNAPHFTK 1138
Score = 104 bits (250), Expect = 2e-20
Identities = 134/511 (26%), Positives = 217/511 (42%), Gaps = 44/511 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D +L + V + + D NDN+PVF ++ + ++ +A V T + +V A D D G NG V
Sbjct: 265 DPRLTANTTVNIKVTDVNDNSPVFTLTS-FTATINESAPVNTTVLQVTASDEDEGLNGEV 323
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANP-SERRYSL 552
+++LQR F+I+P +G V + + E H V A D+ P S + +
Sbjct: 324 VFNLQRDDGF-----FRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMSSQPAYV 378
Query: 553 AVVTIEVTRGTKGNKP-DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYD 609
+++ I + + +PD GA V T++ +I V D + +VS
Sbjct: 379 SIMVININEKPPSLEVLFLPDG-GASQ---VSEAAVADTTLARISVTDPDDGVLTNVSMT 434
Query: 610 LLHGYEEGVPFAVEERSG------VITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NA 662
+ G + F +++ S V T R YD A + N
Sbjct: 435 ITGGAGQ---FDLQKNSNQVYFLIVATTASSFDREEVASYDISIRATDHGSPPQHAEENL 491
Query: 663 TVHVVDVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
T+ V DVND + L H+ II + + G + Q+ T+ G + +
Sbjct: 492 TIAVTDVNDNPPIFDLPLYHATII---EASEPGTPVKQVHATDADE--GVNAQIIYRISP 546
Query: 722 NQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
D +D I G + T + +DRE+ +TVIA ++G IS + + I I D
Sbjct: 547 EGTDYSDWFEINPMSGLVTTLQKVDREETGSVFLTVIAS-DEGEISLSSSVIINITITDV 605
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY---TLFGEGKEMF 837
NDN PVF +Y I+E +I + ATD DEG+ Y T F
Sbjct: 606 NDNQPVFFPGSYNASILEEQEIPYCFLQ---VNATDPDEGSAGQVTYSPSTDLVPTPSQF 662
Query: 838 DVDENTGVVKFIGDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
++ TG + I LDR+ + Y ++ A D GGL S A + +++ D NDN P F +
Sbjct: 663 SINPLTGDLCVI-SRLDRDAGQEEYNFAVKATDGGGLMSHAFVRVILEDINDNVPVFTSL 721
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKF 927
N + I + L + E + +F
Sbjct: 722 --NYRGHIEYDAALGTEVKLVVAEDRDAREF 750
Score = 104 bits (250), Expect = 2e-20
Identities = 125/470 (26%), Positives = 200/470 (42%), Gaps = 41/470 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + D NDN PVF Y+ S++ G + + A D D G G + Y
Sbjct: 1217 LSSSATVYINVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISY- 1275
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+L +SP I ++G +S A + E + L V A D P + S+ V
Sbjct: 1276 -----SLIDSSPKFIIDSSGVISTAAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRI 1330
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGY 614
+++ ++P + Y F N+ T VG + + D + + Y + G
Sbjct: 1331 LDL-------NDNVPIAAMSAYIFTADENIQPPTVVGVVSASDMDVGDNGKIYYYITEGN 1383
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVNDE 672
+ V + V SG + V + Y +A N S + T++++D ND
Sbjct: 1384 DFDV-WDVNHSSGEVYNVRVVDYEMAAHYTLTIIAQDNNVPQTHSTSISVTINILDQNDN 1442
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIA 731
+I+ + + G I + T ++ +G G +R+ I +QD A
Sbjct: 1443 ----TPDFDQDLIYLTLQENVG--INHVLWTVSATDADSGANGLIRYTILTEQDF---FA 1493
Query: 732 IAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG--AGIYQVTIYIEDENDNPPVFE 788
+ E GT+ T + +D E V+ + + A+ +S A V + I D NDN PVF
Sbjct: 1494 VDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSARRAATSTVEVRIYDSNDNNPVFV 1553
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVK 847
+ +ME+ +G + +II ATD D G N YT+ G F +D TG++
Sbjct: 1554 SRSSTD-VMEDEPVG--FNVIHII-ATDEDSGENGRVGYTITSGNEDGKFSLDAVTGLLT 1609
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFNQ 895
I SLD E K Y+L ++A D G + A L I + D ND P F Q
Sbjct: 1610 -IAHSLDHEHKRDYELVILATDHGTVQRMATQTLTIRVIDVNDQPPRFEQ 1658
Score = 101 bits (241), Expect = 2e-19
Identities = 126/462 (27%), Positives = 182/462 (39%), Gaps = 72/462 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P+G +I + A D DSG NG++ Y S K S DA+ G
Sbjct: 1560 VMEDEPVGFNVIHIIATDEDSGENGRVGYTITSGN--EDGKFSLDAVT-----------G 1606
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLN----DNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ +A SL E ++ L I A D G + +++RV DVND P F+++ Y N
Sbjct: 1607 LLTIAHSLDHEHKRDYELVILATDHGTVQRMATQTLTIRVI--DVNDQPPRFEQSIYVMN 1664
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E+Q +G V A D D G N +TY + F I+ TG + LDRE
Sbjct: 1665 VSESQAPGTYVGMVVAIDGDSGVNGRITYELPEEIARGMFRINATTGEIRTKAILDREQR 1724
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
D Y++TV A D G DVNDN+P F P +++
Sbjct: 1725 DSYVVTVYAMD-GAFPARYDMATVLVYVMDVNDNNPTF----------APPTFDITLPEN 1773
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGNGLIL------------YSL 1218
+S +I AT + P G + + D I G I Y+L
Sbjct: 1774 QSPGVIHNAIATDADEGPNGDLIYSITGGDPKNAFSINQSTGAIFTVGALDREDEATYTL 1833
Query: 1219 PQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
Q G S T + VTV D+ D + PVF S Y I E+ +++
Sbjct: 1834 TITATDQ--GTSPRSGTTTIRVTVTDLND-----NDPVFGSMSYYKSIPESTAINATILT 1886
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ T+ E Y +N T F IDP +G + D E + Y V A
Sbjct: 1887 VVATDDDEGLNGDVYYTLDNTT--IGLFSIDPEHGEITTTGKFDYEKETRYTFQVTA--- 1941
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ + G V+V++ I DVNDN+P F
Sbjct: 1942 -------------TDSGVFGPRSERVQVIIDISDVNDNAPVF 1970
Score = 99.1 bits (236), Expect = 8e-19
Identities = 127/491 (25%), Positives = 221/491 (45%), Gaps = 40/491 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
++ + + V + L D NDNNP+F N ++ T I V A D D G NG+ Y
Sbjct: 155 EMFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEAVQPYMTKINGVTATDADEGINGIQGY 214
Query: 498 DLQRTSNLTITSPFKINPN-TGT-VSVAESPILE----GRHALFVEASDQPANPSERRYS 551
+ N+ T + TG + + + L+ + L +EA D +P R +
Sbjct: 215 RIVG-GNIDNTFDLDVRVRETGVYMDIVVNKTLDRETISMYTLIIEAYDG-GDP--RLTA 270
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYD 609
V I+VT + P F + + + + T+V Q+ +D E +V ++
Sbjct: 271 NTTVNIKVTDVNDNS----PVFTLTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVFN 326
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVD 668
L ++G F ++ SG++ + L+ + +DF +A Q+ A + + A V ++
Sbjct: 327 LQR--DDGF-FRIDPASGIVYLNKVLNYEDAQAHDFLVIA-QDKAEPPMSSQPAYVSIMV 382
Query: 669 VN-DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI---ANQQ 724
+N +E+ L+ P + + A A + +++ NV I A Q
Sbjct: 383 ININEKPPSLEVLFLPDGGASQVSEAAVADTTLARISVTDPDDGVLTNVSMTITGGAGQF 442
Query: 725 DV---TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
D+ ++ + T T DRE+ Y +++ A + G +TI + D N
Sbjct: 443 DLQKNSNQVYFLIVAT--TASSFDREEVASYDISIRAT-DHGSPPQHAEENLTIAVTDVN 499
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG---KEMFD 838
DNPP+F+ Y I+E S+ GT +K + ATDADEG NA +Y + EG + F+
Sbjct: 500 DNPPIFDLPLYHATIIEASEPGTPVKQ---VHATDADEGVNAQIIYRISPEGTDYSDWFE 556
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
++ +G+V + +DRE+ L+++A D G LSS + I I D NDN+P F
Sbjct: 557 INPMSGLVTTL-QKVDREETGSVFLTVIASDEGEISLSSSVIINITITDVNDNQPVFFPG 615
Query: 897 EENSKVRIHRE 907
N+ + +E
Sbjct: 616 SYNASILEEQE 626
Score = 98.7 bits (235), Expect = 1e-18
Identities = 78/242 (32%), Positives = 111/242 (45%), Gaps = 19/242 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G +RY L S N F + G + L KE+ +N Q + F + +QA
Sbjct: 951 AMDLDSGDNGLVRYRLTS-NPGNTFRIVEATGEIILNKEVS----YNDQLS-FEVDIQAY 1004
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + + +LD+NDN P F + FY +SI+ENLP V+QV ATD D+G N
Sbjct: 1005 DAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPVSILENLPISTPVVQVEATDNDRGANA 1064
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS 397
TY L ++ F++ PR GWL R VLDRE S+ + + A ++ + A
Sbjct: 1065 LITYTLTPNNDSPYFAVFPREGWLYTRQ--VLDRELKSTFTLTIMASDSGSPPQNSSATV 1122
Query: 398 QRIAKWRRQPLETNAP-LEKTTYVFPDK----VGTKTENIEYYDEQLMSFVNVEVTLLDA 452
Q NAP K +Y F GT+ + +E D L V TL +
Sbjct: 1123 QVTV----VDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTLSPS 1178
Query: 453 ND 454
D
Sbjct: 1179 GD 1180
Score = 98.3 bits (234), Expect = 1e-18
Identities = 122/465 (26%), Positives = 186/465 (40%), Gaps = 33/465 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q M+ + + ++D ND P F S +Y ++ + GT +G V A+D D G NG + Y
Sbjct: 1635 QRMATQTLTIRVIDVNDQPPRFEQS-IYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITY 1693
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA-SDQPANPSERRYSLAVVT 556
+L F+IN TG + E R + V + A P+ RY +A V
Sbjct: 1694 ELPEE---IARGMFRINATTGEIRTKAILDREQRDSYVVTVYAMDGAFPA--RYDMATVL 1748
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN-DAFEQNDVSYDLLHGYE 615
+ V N P F ++ + N G I + D D+ Y + G
Sbjct: 1749 VYVMDVNDNN----PTFAPPTFDITLPENQSPGVIHNAIATDADEGPNGDLIYSITGGDP 1804
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERG 674
+ F++ + +G I V L R + Y A + + S T V V D+ND
Sbjct: 1805 KNA-FSINQSTGAIFTVGALDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDLNDNDP 1863
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIA 733
V G+ S + K AI T +++ G G+V + + N I
Sbjct: 1864 VF--GSMS----YYKSIPESTAINATILTVVATDDDEGLNGDVYYTLDNTTIGLFSID-P 1916
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS-GAGIYQVTIYIEDENDNPPVFEHATY 792
E G I T D EK Y V A + GV + QV I I D NDN PVF+
Sbjct: 1917 EHGEITTTGKFDYEKETRYTFQVTAT-DSGVFGPRSERVQVIIDISDVNDNAPVFKTIPI 1975
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ +++ T + ++A D D G N Y F + F +D TGV+ S
Sbjct: 1976 RANVTQDASSNTFVAN---VEADDKDSGVNGEVNYR-FTQQSSSFAIDTVTGVI--TTKS 2029
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
L+ + Y L ++A D G LSS + + +G +F Q
Sbjct: 2030 LN-PGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQ 2073
Score = 97.9 bits (233), Expect = 2e-18
Identities = 70/216 (32%), Positives = 105/216 (48%), Gaps = 19/216 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ IG++I A+DLDSG NG +RY S P F I E G
Sbjct: 936 IPESTGIGSSIYVATAMDLDSGDNGLVRYRLTSN----PGNT----------FRIVEATG 981
Query: 1000 HVIVAR--SLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+I+ + S + F ++I A D G +L ++++ V + DVND+ PVF +Y ++
Sbjct: 982 EIILNKEVSYNDQLSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPVSIL 1041
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V+ATD D G NA +TY + P++ F + P G L LDRE +
Sbjct: 1042 ENLPISTPVVQVEATDNDRGANALITYTLTPNNDSPYFAVFPREGWLYTRQVLDRELKST 1101
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ LT++A D+G D NDN+P F
Sbjct: 1102 FTLTIMASDSG-SPPQNSSATVQVTVVDANDNAPHF 1136
Score = 96.7 bits (230), Expect = 4e-18
Identities = 121/450 (26%), Positives = 195/450 (43%), Gaps = 72/450 (16%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+ +++A D D G NG I YE S F I+ G V A+SL
Sbjct: 2202 VTQVSATDADEGTNGAIYYEVTSG-------------NTDNAFAIDHVTGIVTTAKSLDY 2248
Query: 1010 ESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E E + L + A DGG+ L ++R+ + DVND+ PVF + +V E +
Sbjct: 2249 EIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVFVQ-MDPVSVSEDLGVGLSVT 2307
Query: 1066 KVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
V ATD+D N N+ Y F + F I +G++++ LDRET+D Y L + A D
Sbjct: 2308 TVTATDSD--TNPNIQYSFTSTGNPGGYFAIDQYSGIITLARSLDRETQDGYTLELEATD 2365
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA 1184
D NDN+P F E + P EL+ N +V+ +
Sbjct: 2366 ----TEYTTTMTLEVIVTDENDNAPVFR--QESYQVTLP---ELTQPNV-AVVAVNASDK 2415
Query: 1185 TIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ-----------QNLGLPSLS 1233
I NA + T + V ++ + +I G+I + N + G P+LS
Sbjct: 2416 DIGLNAEL--TYSFVDSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSGAPALS 2473
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA---PVELVSLNLTEHYENFKM 1290
+ + + DV ++ PVF+ Y + ENV+ + +V+ ++ EN K+
Sbjct: 2474 EFVTVRIEITDVNNQ-----SPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKI 2528
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y+I + ND + F ID +G++ ++ DRE DTY +I+
Sbjct: 2529 NYFIESGND---QGKFKIDANDGSITVLERLDREATDTYTLIIG---------------- 2569
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
A D E + +VV+ ++D+ND+SP F
Sbjct: 2570 -AVDNGEPVNNATAEVVIEVEDINDHSPIF 2598
Score = 93.1 bits (221), Expect = 5e-17
Identities = 87/316 (27%), Positives = 135/316 (42%), Gaps = 15/316 (4%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVP 135
S +SVT+ I D NDN P F ++T+ E + A G + I T+
Sbjct: 1427 STSISVTINILDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTIL 1486
Query: 136 RGLTIFK--DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
F + R N + H ++ S+ + +V YD+
Sbjct: 1487 TEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSARRAATSTVEVRIYDSN 1546
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAI--DQDLGVGATLRYELISGNDRKLFSLDSVNG 251
D V +S + E + IH I D+D G + Y + SGN+ FSLD+V G
Sbjct: 1547 DNNPVFVSRSSTDVMEDEPVGFNVIHIIATDEDSGENGRVGYTITSGNEDGKFSLDAVTG 1606
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
L + LD EH + L + A+ + A + I ++D+ND P FE Y
Sbjct: 1607 LLTIAHSLD--HEHK---RDYELVILATDHGTVQRMATQTLTIRVIDVNDQPPRFEQSIY 1661
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVL 369
+++ E+ G V V+A D D G NG TY+L + +G F I+ +G +R + +L
Sbjct: 1662 VMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPEEIARGMFRINATTG--EIRTKAIL 1719
Query: 370 DREAHSSLRMKVYAKE 385
DRE S + VYA +
Sbjct: 1720 DREQRDSYVVTVYAMD 1735
Score = 91.9 bits (218), Expect = 1e-16
Identities = 87/343 (25%), Positives = 149/343 (43%), Gaps = 21/343 (6%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
++ + A D D G + YE+ SGN F++D V G + K LD + E +++
Sbjct: 2200 IYVTQVSATDADEGTNGAIYYEVTSGNTDNAFAIDHVTGIVTTAKSLDYEIE-----DSY 2254
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VL V A +P T A + I ++D+NDN P F V +S+ E+L G SV V ATD
Sbjct: 2255 VLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVF-VQMDPVSVSEDLGVGLSVTTVTATD 2313
Query: 333 KDQGENGEFTY-QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
D N ++++ +P G F+ID SG +T+ LDRE +++ A +T +
Sbjct: 2314 SDTNPNIQYSFTSTGNPGGYFAIDQYSGIITLARS--LDRETQDGYTLELEATDTEYTTT 2371
Query: 392 GTFA-----DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVE 446
T ++ +R++ + P V V ++I E SFV+
Sbjct: 2372 MTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVAVNASDKDIGLNAELTYSFVDSH 2431
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +F + + EF+ + + + P L + V ++ +N
Sbjct: 2432 PSFYIDPITGVIFT-NQVIEFN-DVETTIQLYVTATDSGAPALSEFVTVRIEITDVNN-- 2487
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR 549
SP + + + SV+E+ L G H + V A D +P +
Sbjct: 2488 -QSPVFVE-DIYSASVSENVSL-GHHVITVVAEDMDLSPENSK 2527
Score = 91.1 bits (216), Expect = 2e-16
Identities = 85/331 (25%), Positives = 146/331 (44%), Gaps = 26/331 (7%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFL-----IAPIGP 126
+G +S +++V + I DVN+ P+F++ Y +V E G + ++P
Sbjct: 2467 SGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENS 2526
Query: 127 SLTIPLTVPRGLTIFKDIRAFDR-----DKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
+ + FK I A D ++ + +D + I+ D+G ++ + V
Sbjct: 2527 KINYFIESGNDQGKFK-IDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVV 2585
Query: 182 LLLRKVLDYDAGDKEFQLV-IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ + + D+ Q +A IL +HA D+D+G + Y +ISG
Sbjct: 2586 IEVEDINDHSPIFDHVQYEGRIAENATASTYIL---TVHATDRDIGYNGEVEYSIISGTY 2642
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
LF++D V+G++ + ELD + ++ F +Q + N L + V I + D N
Sbjct: 2643 SDLFAIDVVSGAVTVRGELDREEVERVE---FTVQASDRGMENQLASV-VLVTITITDFN 2698
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPKGAFSID 355
+ P F FY+ + EN+P V A D D GE GE TY + + F+ID
Sbjct: 2699 EFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIRGLGPSNGDDYFTID 2758
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
P +G V V D E+ +S R V A++T
Sbjct: 2759 PVTG--EVFTAAVFDYESANSYRFVVQAQDT 2787
Score = 89.4 bits (212), Expect = 7e-16
Identities = 116/480 (24%), Positives = 192/480 (40%), Gaps = 60/480 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E I +++NA D D G GQ+ Y ++++ PS+ S IN G
Sbjct: 621 ILEEQEIPYCFLQVNATDPDEGSAGQVTYSPSTDLVPTPSQFS-----------INPLTG 669
Query: 1000 HVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ V L ++ E+ + A DGG L + VRV ++D+ND+ PVF Y ++E
Sbjct: 670 DLCVISRLDRDAGQEEYNFAVKATDGGGLMSHAFVRVILEDINDNVPVFTSLNYRGHIEY 729
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ V A D D + +TY I S D F I+ TG++++ G LD Y
Sbjct: 730 DAALGTEVKLVVAEDRDAREFGRVTYTIDSSTNDGTFAINQTTGLITLVGSLDWVQHPVY 789
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF----YAFDELLEWKHPEADELSNHN 1172
L V+A D G + + P+F YAF + +
Sbjct: 790 TLEVIATDGGGRTSANHAQVTITVAGP-DTSPPEFESSSYAFSVQENAAQVLVGAVKAGH 848
Query: 1173 FESVMMIPVYKATIEENAP-----IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
+ + P+ T+ P I TT ++F + +L ++ Q
Sbjct: 849 IDPGITFPI-TYTLTSGDPNDFFRINTTSGEIFTRGSGPDHEQQAFVLITI-----QAAS 902
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHY 1285
G+P + +TV DV D V P F+++ I E+ + + + + + +
Sbjct: 903 GMPPTYDDVQVNITVIDVNDNV-----PQFMAQTARTSIPESTGIGSSIYVATAMDLDSG 957
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+N +RY + + TF I G + L + + ++EV ++A
Sbjct: 958 DNGLVRYRLTSNPG----NTFRIVEATGEIILNKEVSYNDQLSFEVDIQA---------- 1003
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
Y E LEG + + V I DVNDN P FT G P+ +I P V+Q++
Sbjct: 1004 ---YDAGEPSLEG----SLTLTVIILDVNDNGPVFTMGFYPV--SILENLPISTPVVQVE 1054
Score = 88.2 bits (209), Expect = 2e-15
Identities = 116/456 (25%), Positives = 196/456 (42%), Gaps = 50/456 (10%)
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
+L GTA I V + + V Q+ P+ + E++ +G ++ + A D D+ N I+Y
Sbjct: 2267 QLTGTATMRIGIVDVNDNQPVFV-QMDPVS-VSEDLGVGLSVTTVTATDSDT--NPNIQY 2322
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLN 1026
F S P YF I++ G + +ARSL E++ + L + A D
Sbjct: 2323 SFTSTGN--PGG----------YFAIDQYSGIITLARSLDRETQDGYTLELEATDT-EYT 2369
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+++ V V D ND+ PVF++ Y + E + V+A+D D G NA LTY
Sbjct: 2370 TTMTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVAVNASDKDIGLNAELTYSF-- 2427
Query: 1087 SDTDLPFEISPLTGVLSVNGELD-RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
D+ F I P+TGV+ N ++ + E L V A D+G DVN
Sbjct: 2428 VDSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSG-APALSEFVTVRIEITDVN 2486
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESV---MMIPVYKATIEENAPIGTTVAKVFAN 1202
+ SP F +++ E L +H V M + + I G K F
Sbjct: 2487 NQSPVF--VEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIESGNDQGK-FKI 2543
Query: 1203 DTDFIGNGNGLILYSLPQRKNQQ--------NLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
D + +G+ +L L + + G P ++TA +++ V D+ D
Sbjct: 2544 DAN---DGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVEDINDH-----S 2595
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRN 1312
P+F YE I EN A +++++ T+ N ++ Y I++ +D+ F ID +
Sbjct: 2596 PIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGTYSDL---FAIDVVS 2652
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
G + + DRE + E V+A + +L ++
Sbjct: 2653 GAVTVRGELDREEVERVEFTVQASDRGMENQLASVV 2688
Score = 85.4 bits (202), Expect = 1e-14
Identities = 105/418 (25%), Positives = 174/418 (41%), Gaps = 34/418 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVLY 497
L FV V + + D N+ +PVFV ++Y S+ N +G + V A D DL +N + Y
Sbjct: 2472 LSEFVTVRIEITDVNNQSPVFV-EDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINY 2530
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
++ ++ FKI+ N G+++V E E + L + A D N + A V
Sbjct: 2531 FIESGND---QGKFKIDANDGSITVLERLDREATDTYTLIIGAVD---NGEPVNNATAEV 2584
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHG 613
IEV + P F YE + N T + + D +V Y ++ G
Sbjct: 2585 VIEV----EDINDHSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISG 2640
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVND 671
+ FA++ SG +TV +L R +F A L+ V T+ + D N+
Sbjct: 2641 TYSDL-FAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITITDFNE 2699
Query: 672 ERGVLLK-GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ H + ++ + G + N + YG T ++R L + D D
Sbjct: 2700 FPPYFPQLFYHFLVPENMPVETYVFTAGAL--DNDAGEYGELTYSIRGLGPSNGD--DYF 2755
Query: 731 AIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
I G +FT D E + YR V A+ G+ Q + I ++ PP+F
Sbjct: 2756 TIDPVTGEVFTAAVFDYESANSYRFVVQAQDTGGLSISI---QTEVNITSVDEFPPMFND 2812
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
Y I + + G + + ATDAD G + + +Y+L E F ++ TG++K
Sbjct: 2813 QEYYFEIGDGADAGDYVGQ---VTATDADGGEDGVVIYSL---THEFFYIEATTGIIK 2864
Score = 85.0 bits (201), Expect = 1e-14
Identities = 115/474 (24%), Positives = 193/474 (40%), Gaps = 53/474 (11%)
Query: 445 VEVTLLDANDNNP----VFVPSNLYEFSMKSNAKVG-TVIGKVKAVDPDLG--------- 490
V + +++ N+ P +F+P S S A V T + ++ DPD G
Sbjct: 378 VSIMVININEKPPSLEVLFLPDG--GASQVSEAAVADTTLARISVTDPDDGVLTNVSMTI 435
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
G +DLQ+ SN F I T + E + + + A+D + P
Sbjct: 436 TGGAGQFDLQKNSNQVY---FLIVATTASSFDREEV---ASYDISIRATDHGSPPQHAEE 489
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
+L + +V D P P Y + GT V Q+ DA E +
Sbjct: 490 NLTIAVTDVN--------DNPPIFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQII 541
Query: 608 YDLL-HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVH 665
Y + G + F + SG++T + + R +A E +LS +
Sbjct: 542 YRISPEGTDYSDWFEINPMSGLVTTLQKVDREETGSVFLTVIASDEGEISLSSSVIINIT 601
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
+ DVND + V G+++ I ++E Q+ T+ G V + +
Sbjct: 602 ITDVNDNQPVFFPGSYNASI--LEEQEIPYCFLQVNATDPDE---GSAGQVTYSPSTDLV 656
Query: 726 VT-DDIAIAE-DGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
T +I G + LDR+ ++ Y V A G++S A V + +ED ND
Sbjct: 657 PTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAVKATDGGGLMSHAF---VRVILEDIND 713
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDE 841
N PVF Y G I ++ +GTE+K ++ A D D YT+ + F +++
Sbjct: 714 NVPVFTSLNYRGHIEYDAALGTEVK---LVVAEDRDAREFGRVTYTIDSSTNDGTFAINQ 770
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS--EAELIIMIGDENDNKPEF 893
TG++ +G SLD + +Y L ++A D GG +S A++ I + + + PEF
Sbjct: 771 TTGLITLVG-SLDWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEF 823
Score = 82.2 bits (194), Expect = 1e-13
Identities = 101/413 (24%), Positives = 172/413 (41%), Gaps = 48/413 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E P G + + A D DSG+ G I Y ++ F+I+ G
Sbjct: 1247 VREEQPAGEFVAWIIATDTDSGVLGNISYSL---------------IDSSPKFIIDSS-G 1290
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A ++ E E + L + A DGGN + SVRV + D+ND+ P+ + Y F +
Sbjct: 1291 VISTAAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRILDLNDNVPIAAMSAYIFTAD 1350
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E V+G V A+D D G N + Y+I + +D D+ ++++ +G + +D E
Sbjct: 1351 ENIQPPTVVGVVSASDMDVGDNGKIYYYITEGNDFDV-WDVNHSSGEVYNVRVVDYEMAA 1409
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y LT++A+DN D NDN+P FD+ L + + + NH
Sbjct: 1410 HYTLTIIAQDNNVPQTHSTSISVTINILDQNDNTPD---FDQDLIYLTLQENVGINHVLW 1466
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG----NGNGLILYSLPQRKNQQNLGLP 1230
+V AT ++ G + + DF G + ++ N L +
Sbjct: 1467 TV------SATDADSGANG-LIRYTILTEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVI 1519
Query: 1231 SLSSTAILMVTVADVPDEVEM------SDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
AI + VE+ + PVF+SR ++ E+ ++ + T+
Sbjct: 1520 QAQDQAINVSARRAATSTVEVRIYDSNDNNPVFVSR-SSTDVMEDEPVGFNVIHIIATDE 1578
Query: 1285 --YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
EN ++ Y I + N+ F +D G L + S D E K YE+++ A
Sbjct: 1579 DSGENGRVGYTITSGNEDG---KFSLDAVTGLLTIAHSLDHEHKRDYELVILA 1628
Score = 81.8 bits (193), Expect = 1e-13
Identities = 47/126 (37%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V+V + D ND+ P F + Y V E + + +V ATDAD G N + Y + +T
Sbjct: 2168 TVQVELTDANDNAPQFVQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVTSGNT 2227
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
D F I +TG+++ LD E ED Y+LTVVARD G DVNDN P
Sbjct: 2228 DNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGG-SPQLTGTATMRIGIVDVNDNQP 2286
Query: 1150 KFYAFD 1155
F D
Sbjct: 2287 VFVQMD 2292
Score = 81.4 bits (192), Expect = 2e-13
Identities = 49/146 (33%), Positives = 75/146 (51%), Gaps = 5/146 (3%)
Query: 1011 SEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+ + ++I A D G+ + ++ + V DVND+ P+F Y+ + EA + +V
Sbjct: 469 ASYDISIRATDHGSPPQHAEENLTIAVTDVNDNPPIFDLPLYHATIIEASEPGTPVKQVH 528
Query: 1069 ATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
ATDAD G NA + Y I P TD FEI+P++G+++ ++DRE LTV+A D G
Sbjct: 529 ATDADEGVNAQIIYRISPEGTDYSDWFEINPMSGLVTTLQKVDREETGSVFLTVIASDEG 588
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFY 1152
DVNDN P F+
Sbjct: 589 -EISLSSSVIINITITDVNDNQPVFF 613
Score = 81.0 bits (191), Expect = 2e-13
Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 11/199 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G L Y + G+ + FS++ G++F LD + E T+ L + A+
Sbjct: 1784 ATDADEGPNGDLIYSITGGDPKNAFSINQSTGAIFTVGALDREDEA-----TYTLTITAT 1838
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
++ + + + DLNDN P F Y SI E+ ++L V+ATD D+G NG
Sbjct: 1839 DQGTSPRSGTTTIRVTVTDLNDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNG 1898
Query: 340 EFTYQLDDPK-GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
+ Y LD+ G FSIDP G +T + D E + +V A T+ V G ++
Sbjct: 1899 DVYYTLDNTTIGLFSIDPEHGEITTTGK--FDYEKETRYTFQVTA--TDSGVFGPRSERV 1954
Query: 399 RIAKWRRQPLETNAPLEKT 417
++ + NAP+ KT
Sbjct: 1955 QVI-IDISDVNDNAPVFKT 1972
Score = 80.6 bits (190), Expect = 3e-13
Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 26/236 (11%)
Query: 927 FALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
+ +DV+ P F +PEN G I A D D G NG + Y
Sbjct: 1750 YVMDVNDNNPTFAPPTFDITLPENQSPGV-IHNAIATDADEGPNGDLIYSITGG------ 1802
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNL--NDNISVRVFV 1035
+ K F IN+ G + +L E E + L I+A D G + ++RV V
Sbjct: 1803 -------DPKNAFSINQSTGAIFTVGALDREDEATYTLTITATDQGTSPRSGTTTIRVTV 1855
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D+ND+ PVF Y ++ E+ + V ATD D G N ++ Y + + L F I
Sbjct: 1856 TDLNDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNGDVYYTLDNTTIGL-FSI 1914
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
P G ++ G+ D E E +Y V A D+G DVNDN+P F
Sbjct: 1915 DPEHGEITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVF 1970
Score = 80.2 bits (189), Expect = 4e-13
Identities = 53/167 (31%), Positives = 80/167 (47%), Gaps = 12/167 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLD------SVNGSLFLEKELDLDAEHNLQANT 271
+ A D D G+ Y ++ GN F LD V + + K LD + +
Sbjct: 199 VTATDADEGINGIQGYRIVGGNIDNTFDLDVRVRETGVYMDIVVNKTLDRET-----ISM 253
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ L ++A +P TA V I++ D+NDN P F + + +I E+ P +VLQV A+
Sbjct: 254 YTLIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTAS 313
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN-QTVLDREAHSSL 377
D+D+G NGE + L G F IDP SG + + D +AH L
Sbjct: 314 DEDEGLNGEVVFNLQRDDGFFRIDPASGIVYLNKVLNYEDAQAHDFL 360
Score = 80.2 bits (189), Expect = 4e-13
Identities = 84/310 (27%), Positives = 130/310 (41%), Gaps = 13/310 (4%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-EKAFIFLIAP-IGPSLTIPLTV-PRGL 138
+V V + D NDN P F YH ++E P G E + + P +GP+ + T+ P G
Sbjct: 1121 TVQVTVVDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTLSPSGD 1180
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYS-IVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
+ P + Y I+ D G+ AL SS + + + D +A
Sbjct: 1181 FTIDEEGVIRTTHPLDREAAYSYRLIIRAVDGGNPALSSSATVYINVNDLND-NAPVFSQ 1239
Query: 198 QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEK 257
AS + F I A D D GV + Y LI + + F +DS +G +
Sbjct: 1240 DRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISYSLIDSSPK--FIIDS-SGVISTAA 1296
Query: 258 ELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE 317
+D + E + + L V A NP A A V + +LDLNDN+P + Y + E
Sbjct: 1297 AIDREDE-----SYYTLTVLAQDGGNPPMQATASVRVRILDLNDNVPIAAMSAYIFTADE 1351
Query: 318 NLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSL 377
N+ V V A+D D G+NG+ Y + + D V N V+D E +
Sbjct: 1352 NIQPPTVVGVVSASDMDVGDNGKIYYYITEGNDFDVWDVNHSSGEVYNVRVVDYEMAAHY 1411
Query: 378 RMKVYAKETN 387
+ + A++ N
Sbjct: 1412 TLTIIAQDNN 1421
Score = 79.8 bits (188), Expect = 5e-13
Identities = 66/214 (30%), Positives = 99/214 (46%), Gaps = 25/214 (11%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT + +++A D D G+N QI Y ++S + + +F IN G V +
Sbjct: 521 GTPVKQVHATDADEGVNAQIIY-----------RISPEGTDYSDWFEINPMSGLVTTLQK 569
Query: 1007 LPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
+ E L + A D G +L+ ++ + + + DVND+ PVF YN ++ E Q
Sbjct: 570 VDREETGSVFLTVIASDEGEISLSSSVIINITITDVNDNQPVFFPGSYNASILEEQEIPY 629
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLP----FEISPLTGVLSVNGELDRET-EDKYI 1117
+V+ATD D G +TY PS +P F I+PLTG L V LDR+ +++Y
Sbjct: 630 CFLQVNATDPDEGSAGQVTY--SPSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYN 687
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V A D G D+NDN P F
Sbjct: 688 FAVKATDGG---GLMSHAFVRVILEDINDNVPVF 718
Score = 78.6 bits (185), Expect = 1e-12
Identities = 53/172 (30%), Positives = 87/172 (50%), Gaps = 10/172 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D GV + YEL R +F +++ G + + LD + Q +++V+ V A
Sbjct: 1680 AIDGDSGVNGRITYELPEEIARGMFRINATTGEIRTKAILDRE-----QRDSYVVTVYAM 1734
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + A V + ++D+NDN P F ++I++ EN G + +ATD D+G NG
Sbjct: 1735 DGAFPARYDMATVLVYVMDVNDNNPTFAPPTFDITLPENQSPGV-IHNAIATDADEGPNG 1793
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+ Y + DPK AFSI+ +G + LDRE ++ + + A + S
Sbjct: 1794 DLIYSITGGDPKNAFSINQSTG--AIFTVGALDREDEATYTLTITATDQGTS 1843
Score = 77.0 bits (181), Expect = 4e-12
Identities = 54/182 (29%), Positives = 88/182 (48%), Gaps = 11/182 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+D+G+ A L Y + + F +D + G +F + + E N T L V
Sbjct: 2410 VNASDKDIGLNAELTYSFVDSHPS--FYIDPITGVIFTNQVI----EFNDVETTIQLYVT 2463
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
A+ P + V IE+ D+N+ P F D Y+ S+ EN+ G V+ V+A D D
Sbjct: 2464 ATDSGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSP 2523
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
EN + Y ++ + +G F ID G +TV + LDREA + + + A + V
Sbjct: 2524 ENSKINYFIESGNDQGKFKIDANDGSITVLER--LDREATDTYTLIIGAVDNGEPVNNAT 2581
Query: 395 AD 396
A+
Sbjct: 2582 AE 2583
Score = 77.0 bits (181), Expect = 4e-12
Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 27/235 (11%)
Query: 930 DVDQLGPLFL-------IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKL 981
DV+ P+F+ + EN+ +G +I + A D+D S N +I Y S
Sbjct: 2484 DVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIESG-------- 2535
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVF--VKD 1037
+ F I+ G + V L E+ + L I A+D G +N + V V+D
Sbjct: 2536 -----NDQGKFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVED 2590
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEIS 1096
+NDH P+F Y + E + V ATD D G N + Y I + +DL F I
Sbjct: 2591 INDHSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGTYSDL-FAID 2649
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++G ++V GELDRE ++ TV A D G D N+ P F
Sbjct: 2650 VVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITITDFNEFPPYF 2704
Score = 75.4 bits (177), Expect = 1e-11
Identities = 76/329 (23%), Positives = 145/329 (44%), Gaps = 28/329 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFL-DTPYHVTVDELTPTGE-KAFIF-------L 120
+ G +S+ +V + + D+NDN P+F D Y +V E P GE A+I +
Sbjct: 1210 VDGGNPALSSSATVYINVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDTDSGV 1269
Query: 121 IAPIGPSL--TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESS 177
+ I SL + P + + A DR+ + +Y++ V D G+ ++++
Sbjct: 1270 LGNISYSLIDSSPKFIIDSSGVISTAAAIDRE------DESYYTLTVLAQDGGNPPMQAT 1323
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
+ + + D + I + + I + + A D D+G + Y +
Sbjct: 1324 ASVRVRILDLND-NVPIAAMSAYIFTADENIQPPTVVGV-VSASDMDVGDNGKIYYYITE 1381
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIEL 296
GND ++ ++ +G ++ + +D + A + L + A N P + V I +
Sbjct: 1382 GNDFDVWDVNHSSGEVYNVRVVDYE-----MAAHYTLTIIAQDNNVPQTHSTSISVTINI 1436
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
LD NDN P+F+ D +++ EN+ + V ATD D G NG Y + + F++D
Sbjct: 1437 LDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTILTEQDFFAVDE 1496
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G T+R +D E + + + A++
Sbjct: 1497 YTG--TLRTIQNVDHEINHVFLLVIQAQD 1523
Score = 74.1 bits (174), Expect = 3e-11
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 12/234 (5%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV-YIP 977
I + +N D DQ + EN+ I + ++A D DSG NG IRY +E +
Sbjct: 1434 INILDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTILTEQDFFA 1493
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKD 1037
+ + ++ ++ HV + + + +N+SA + VR++ D
Sbjct: 1494 VDEYTGTLRTIQN---VDHEINHVFLL--VIQAQDQAINVSARRAA--TSTVEVRIY--D 1544
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ PVF +E+ V+ + ATD D G+N + Y I + D F +
Sbjct: 1545 SNDNNPVFVSRSSTDVMEDEPVGFNVI-HIIATDEDSGENGRVGYTITSGNEDGKFSLDA 1603
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+TG+L++ LD E + Y L ++A D+G DVND P+F
Sbjct: 1604 VTGLLTIAHSLDHEHKRDYELVILATDHG-TVQRMATQTLTIRVIDVNDQPPRF 1656
Score = 73.7 bits (173), Expect = 3e-11
Identities = 95/415 (22%), Positives = 165/415 (39%), Gaps = 36/415 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRY---EFNSEVYIPPSKLSADALEVKRYFVINE 996
I +N+P+ T++ ++ D+ L +++ E + D+ F IN+
Sbjct: 711 INDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTIDSSTNDGTFAINQ 770
Query: 997 RHGHVIVARSLP--PESEFRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNF 1052
G + + SL + L + A DGG ++ V + V + P F+ + Y F
Sbjct: 771 TTGLITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEFESSSYAF 830
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+V+E + ++G V A D G +TY + D + F I+ +G + G
Sbjct: 831 SVQE-NAAQVLVGAVKAGHIDPGITFPITYTLTSGDPNDFFRINTTSGEIFTRGSGPDHE 889
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ ++L + +G DVNDN P+F A + PE+ + +
Sbjct: 890 QQAFVLITIQAASGMPPTYDDVQVNITVI-DVNDNVPQFMA--QTARTSIPESTGIGS-- 944
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ------- 1225
S+ + +N + + N T I G I+ + N Q
Sbjct: 945 --SIYVATAMDLDSGDNGLVRYRLTSNPGN-TFRIVEATGEIILNKEVSYNDQLSFEVDI 1001
Query: 1226 ---NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLN 1280
+ G PSL + L V + DV D + PVF +Y + I EN ++ PV V
Sbjct: 1002 QAYDAGEPSLEGSLTLTVIILDVND-----NGPVFTMGFYPVSILENLPISTPVVQVEAT 1056
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N + Y + ND+ F + PR G LY + DRE+K T+ + + A
Sbjct: 1057 DNDRGANALITYTLTPNNDSPY---FAVFPREGWLYTRQVLDRELKSTFTLTIMA 1108
Score = 72.9 bits (171), Expect = 6e-11
Identities = 73/326 (22%), Positives = 141/326 (43%), Gaps = 22/326 (6%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT--IPLT 133
+++A +V + + DVNDN P+F T + T++E P + L +
Sbjct: 267 RLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVFN 326
Query: 134 VPRGLTIFKDIRA----FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
+ R F+ A + N ++ H +V D + S +P + V++
Sbjct: 327 LQRDDGFFRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMSS--QPAYVSIMVIN 384
Query: 190 YDAGDKEFQLVIMASG--KRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLF 244
+ +++ + G ++ + + + I D D GV + + G +
Sbjct: 385 INEKPPSLEVLFLPDGGASQVSEAAVADTTLARISVTDPDDGVLTNVSMTITGGAGQFDL 444
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+S N FL + + ++ + ++A+ +P + A+ + I + D+NDN P
Sbjct: 445 QKNS-NQVYFLIVATTASSFDREEVASYDISIRATDHGSPPQHAEENLTIAVTDVNDNPP 503
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-----FSIDPRSG 359
F++ Y+ +I+E G V QV ATD D+G N + Y++ P+G F I+P SG
Sbjct: 504 IFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRI-SPEGTDYSDWFEINPMSG 562
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE 385
+T + +DRE S+ + V A +
Sbjct: 563 LVTTLQK--VDREETGSVFLTVIASD 586
Score = 71.3 bits (167), Expect = 2e-10
Identities = 109/462 (23%), Positives = 177/462 (38%), Gaps = 58/462 (12%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
P T I + A D D G+NG Y L E Y ++V
Sbjct: 191 PYMTKINGVTATDADEGINGIQGYRIVGGNIDNTFDLDVRVRETGVYM-------DIVVN 243
Query: 1005 RSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
++L E S + L I A DGG+ L N +V + V DVND+ PVF T + + E+
Sbjct: 244 KTLDRETISMYTLIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPV 303
Query: 1061 RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
+ +V A+D D G N + + +Q D F I P +G++ +N L+ E + V
Sbjct: 304 NTTVLQVTASDEDEGLNGEVVFNLQRDDGF--FRIDPASGIVYLNKVLNYEDAQAHDFLV 361
Query: 1121 VARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIP 1180
+A+D ++N+ P E+L A ++S +
Sbjct: 362 IAQDKAEPPMSSQPAYVSIMVININEKPPSL----EVLFLPDGGASQVSEAAVADTTLAR 417
Query: 1181 VYKATIEENAPIGTTVAKVF---ANDTDFIGNGNG---LILYSLPQRKNQQNL------- 1227
+ + + + + T V+ A D N N LI+ + +++ +
Sbjct: 418 I--SVTDPDDGVLTNVSMTITGGAGQFDLQKNSNQVYFLIVATTASSFDREEVASYDISI 475
Query: 1228 -----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
G P + L + V DV D + D P++ + E PV+ V
Sbjct: 476 RATDHGSPPQHAEENLTIAVTDVNDNPPIFDLPLYHATIIE---ASEPGTPVKQVHATDA 532
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
+ N ++ Y I E TD F I+P +G + ++ DRE +T V +
Sbjct: 533 DEGVNAQIIYRISPEG-TDYSDWFEINPMSGLVTTLQKVDRE--ETGSVFLTV------- 582
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
+A D E V + + I DVNDN P F G+
Sbjct: 583 --------IASDEGEISLSSSVIINITITDVNDNQPVFFPGS 616
Score = 71.3 bits (167), Expect = 2e-10
Identities = 52/166 (31%), Positives = 77/166 (46%), Gaps = 7/166 (4%)
Query: 233 YELISGNDRKLFSLD-SVNGSLFLEKELDLDAEHNLQANT-FVLQVQASQLNNPLKTAQA 290
Y L+SGN+ F + GS L ++ Q N V + + N+ A
Sbjct: 2108 YSLVSGNENGAFGIQVQAGGSAILVVADTTKLDYETQPNIRLVAEAMRTPENSSPMYGYA 2167
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDP 348
V++EL D NDN P+F D Y + E + V QV ATD D+G NG Y++ +
Sbjct: 2168 TVQVELTDANDNAPQFVQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVTSGNT 2227
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
AF+ID +G +T LD E S + V A++ +P + GT
Sbjct: 2228 DNAFAIDHVTGIVTTAKS--LDYEIEDSYVLTVVARDGGSPQLTGT 2271
Score = 70.9 bits (166), Expect = 2e-10
Identities = 58/188 (30%), Positives = 87/188 (46%), Gaps = 16/188 (8%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I + N+F QL FL+PEN+P+ T + ALD D+G G++ Y + P
Sbjct: 2692 ITITDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIRG---LGP 2748
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVK 1036
S + D YF I+ G V A ES +R + A D G L+ +I V +
Sbjct: 2749 S--NGDD-----YFTIDPVTGEVFTAAVFDYESANSYRFVVQAQDTGGLSISIQTEVNIT 2801
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
V++ P+F Y F + + +G+V ATDAD G++ + Y S T F I
Sbjct: 2802 SVDEFPPMFNDQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIY----SLTHEFFYIE 2857
Query: 1097 PLTGVLSV 1104
TG++ V
Sbjct: 2858 ATTGIIKV 2865
Score = 67.3 bits (157), Expect = 3e-09
Identities = 72/293 (24%), Positives = 124/293 (42%), Gaps = 18/293 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-KAFIFLIAPIGPSLTIPLTVPRG--- 137
+V VY+ DVNDN P F + +T+ E G I A GP+ + ++ G
Sbjct: 1746 TVLVYVMDVNDNNPTFAPPTFDITLPENQSPGVIHNAIATDADEGPNGDLIYSITGGDPK 1805
Query: 138 --LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDA-- 192
+I + A + Y++ ++ D G + + + + D D
Sbjct: 1806 NAFSINQSTGAIFTVGALDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDLNDNDPVF 1865
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
G + I S I+ IL + A D D G+ + Y L LFS+D +G
Sbjct: 1866 GSMSYYKSIPES-TAINATIL---TVVATDDDEGLNGDVYYTL-DNTTIGLFSIDPEHGE 1920
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ + D + E TF + S + P ++ + +V I++ D+NDN P F+
Sbjct: 1921 ITTTGKFDYEKETRY---TFQVTATDSGVFGP-RSERVQVIIDISDVNDNAPVFKTIPIR 1976
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
++ ++ + V V A DKD G NGE Y+ +F+ID +G +T ++
Sbjct: 1977 ANVTQDASSNTFVANVEADDKDSGVNGEVNYRFTQQSSSFAIDTVTGVITTKS 2029
Score = 65.7 bits (153), Expect = 9e-09
Identities = 79/319 (24%), Positives = 136/319 (42%), Gaps = 27/319 (8%)
Query: 582 VGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP 641
V N +GT VG ++ + +F + L+ E F +E +G+IT L R P
Sbjct: 90 VKENQPVGTFVGSLQDDTSFGS---PFTTLNPSAE---FMIESDTGIITTGAVLDRETAP 143
Query: 642 MYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE--NSAGAAIGQ 699
+F + ++V T+ + D ND + + + F V E I
Sbjct: 144 DQEFVIIVFAGEMFTALVV--TIRLNDTNDNNPIFSQDNRT---FEVTEAVQPYMTKING 198
Query: 700 IFHTNMSSIYGNGTGNVRFLIANQQDVTD-DIAIAEDGT---IFTQKPLDREKRDVYRMT 755
+ T+ NG R + N + D D+ + E G I K LDRE +Y +
Sbjct: 199 VTATDADEGI-NGIQGYRIVGGNIDNTFDLDVRVRETGVYMDIVVNKTLDRETISMYTL- 256
Query: 756 VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
+I ++ G V I + D NDN PVF ++ I E++ + T + + A+
Sbjct: 257 IIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQ---VTAS 313
Query: 816 DADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GL 873
D DEG N ++ L F +D +G+V ++ L+ E + ++A+D +
Sbjct: 314 DEDEGLNGEVVFNL-QRDDGFFRIDPASGIV-YLNKVLNYEDAQAHDFLVIAQDKAEPPM 371
Query: 874 SSE-AELIIMIGDENDNKP 891
SS+ A + IM+ + N+ P
Sbjct: 372 SSQPAYVSIMVININEKPP 390
Score = 65.7 bits (153), Expect = 9e-09
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 13/162 (8%)
Query: 218 IHAIDQDLGVGATLRYELI-SGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+HA D D GV A + Y + G D F ++ ++G + +++D + + + L
Sbjct: 527 VHATDADEGVNAQIIYRISPEGTDYSDWFEINPMSGLVTTLQKVDRE-----ETGSVFLT 581
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V AS ++ + I + D+NDN P F YN SI+E + LQV ATD D+
Sbjct: 582 VIASDEGEISLSSSVIINITITDVNDNQPVFFPGSYNASILEEQEIPYCFLQVNATDPDE 641
Query: 336 GENGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREA 373
G G+ TY L FSI+P +G L V ++ LDR+A
Sbjct: 642 GSAGQVTYSPSTDLVPTPSQFSINPLTGDLCVISR--LDRDA 681
Score = 65.7 bits (153), Expect = 9e-09
Identities = 75/325 (23%), Positives = 128/325 (39%), Gaps = 16/325 (4%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPY--HVTVDELTPTGEKAFIFL---IAPIGP-SLTI 130
+ ++ V V +ED+NDNVP+F Y H+ D T K + G + TI
Sbjct: 698 LMSHAFVRVILEDINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTI 757
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTP-NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
+ G + Y++ DG ++H V + V
Sbjct: 758 DSSTNDGTFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQVTIT--VAG 815
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
D EF+ A + + + + A D G+ + Y L SG+ F +++
Sbjct: 816 PDTSPPEFESSSYAFSVQENAAQVLVGAVKAGHIDPGITFPITYTLTSGDPNDFFRINTT 875
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G +F +H QA FVL + P +V I ++D+NDN+P+F
Sbjct: 876 SGEIFTRGS---GPDHEQQA--FVLITIQAASGMPPTYDDVQVNITVIDVNDNVPQFMAQ 930
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTV 368
SI E+ G S+ A D D G+NG Y+L +P F I +G + + +
Sbjct: 931 TARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRLTSNPGNTFRIVEATGEIILNKEVS 990
Query: 369 LDREAHSSLRMKVYAKETNPSVVGT 393
+ + + ++ Y PS+ G+
Sbjct: 991 YNDQLSFEVDIQAY-DAGEPSLEGS 1014
Score = 65.3 bits (152), Expect = 1e-08
Identities = 115/459 (25%), Positives = 181/459 (39%), Gaps = 58/459 (12%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F ENI T + ++A D+D G NG+I Y YI D +V N
Sbjct: 1346 IFTADENIQPPTVVGVVSASDMDVGDNGKIYY------YITEGN-DFDVWDV------NH 1392
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
G V R + E + + L I A D + +ISV + + D ND+ P F +
Sbjct: 1393 SSGEVYNVRVVDYEMAAHYTLTIIAQDNNVPQTHSTSISVTINILDQNDNTPDFDQDLIY 1452
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
++E VL V ATDAD G N + Y I ++ D F + TG L +D E
Sbjct: 1453 LTLQENVGINHVLWTVSATDADSGANGLIRYTIL-TEQDF-FAVDEYTGTLRTIQNVDHE 1510
Query: 1112 TEDKYILTVVARDN--GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
++L + A+D D NDN+P F + DE
Sbjct: 1511 INHVFLLVIQAQDQAINVSARRAATSTVEVRIYDSNDNNPVFVSRSS----TDVMEDEPV 1566
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL--ILYSL--PQRKNQQ 1225
N V+ I EN +G T+ + + GL I +SL +++ +
Sbjct: 1567 GFN---VIHIIATDEDSGENGRVGYTITSGNEDGKFSLDAVTGLLTIAHSLDHEHKRDYE 1623
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPV-FISRYYELEIEENVNAPVELVSLNLT-- 1282
+ L + T M T ++++D+P F Y + + E+ AP V + +
Sbjct: 1624 LVILATDHGTVQRMATQTLTIRVIDVNDQPPRFEQSIYVMNVSES-QAPGTYVGMVVAID 1682
Query: 1283 -EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
+ N ++ Y + E R F I+ G + DRE +D+Y V V Y+
Sbjct: 1683 GDSGVNGRITYELPEE---IARGMFRINATTGEIRTKAILDREQRDSYVVTV------YA 1733
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ +P D+ V+V + DVNDN+P F
Sbjct: 1734 MD---GAFPARYDM--------ATVLVYVMDVNDNNPTF 1761
Score = 63.7 bits (148), Expect = 4e-08
Identities = 68/249 (27%), Positives = 103/249 (41%), Gaps = 22/249 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL S V V +T+ D N+ P F P Y F + N V T + A+D D G+ G +
Sbjct: 2681 ENQLASVVLVTITITDFNEFPPYF-PQLFYHFLVPENMPVETYVFTAGALDNDAGEYGEL 2739
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
Y ++ F I+P TG V A E ++ V+A D S++
Sbjct: 2740 TYSIRGLGPSNGDDYFTIDPVTGEVFTAAVFDYESANSYRFVVQAQDTGG------LSIS 2793
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLL 611
+ T EV + P P F Y F +G G VGQ+ DA E V Y L
Sbjct: 2794 IQT-EVNITSVDEFP--PMFNDQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIYSLT 2850
Query: 612 HGYEEGVPFAVEERSGVITVVDDL---SRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
H + F +E +G+I V L +R R + D + +LS +N + ++
Sbjct: 2851 HEF-----FYIEATTGIIKVAKPLNSSARKRRGLEDRFTHRSRREIDLSAQSNFALKIIA 2905
Query: 669 VNDERGVLL 677
+ G L+
Sbjct: 2906 STGKPGTLI 2914
Score = 63.3 bits (147), Expect = 5e-08
Identities = 50/170 (29%), Positives = 75/170 (44%), Gaps = 23/170 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ I TI+ + A D D GLNG + Y ++ F I+ HG
Sbjct: 1874 IPESTAINATILTVVATDDDEGLNGDVYYTLDNTTI--------------GLFSIDPEHG 1919
Query: 1000 HVIVARSLPPESEFR--LNISALDGGNL---NDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ E E R ++A D G ++ + V + + DVND+ PVFK NV
Sbjct: 1920 EITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTIPIRANV 1979
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLS 1103
+ + + V+A D D G N + Y F Q S + F I +TGV++
Sbjct: 1980 TQDASSNTFVANVEADDKDSGVNGEVNYRFTQQSSS---FAIDTVTGVIT 2026
Score = 62.9 bits (146), Expect = 7e-08
Identities = 53/158 (33%), Positives = 72/158 (45%), Gaps = 13/158 (8%)
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA--QY 1059
++ R P+ EF + + A G + + V + + D ND+ P+F + F V EA Y
Sbjct: 136 VLDRETAPDQEFVIIVFA---GEMFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEAVQPY 192
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL---TGV---LSVNGELDRETE 1113
++ G V ATDAD G N Y I + D F++ TGV + VN LDRET
Sbjct: 193 MTKING-VTATDADEGINGIQGYRIVGGNIDNTFDLDVRVRETGVYMDIVVNKTLDRETI 251
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y L + A D G DVNDNSP F
Sbjct: 252 SMYTLIIEAYDGG-DPRLTANTTVNIKVTDVNDNSPVF 288
Score = 58.4 bits (135), Expect = 1e-06
Identities = 81/327 (24%), Positives = 137/327 (41%), Gaps = 42/327 (12%)
Query: 82 SVTVYIEDVNDNVPIFLDTP-YHVTVDELTPTGEKA---------------FIFLIAPIG 125
++T+ + DVNDN PIF D P YH T+ E + G I+ I+P G
Sbjct: 490 NLTIAVTDVNDNPPIF-DLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRISPEG 548
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ + + ++ DR++ + V ++++ +D+G +L SS ++
Sbjct: 549 TDYSDWFEINPMSGLVTTLQKVDREETGS----VFLTVIA-SDEGEISLSSS-----VII 598
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPE---PIHAIDQDLGVGATLRYELISG--ND 240
+ D D + + I +E P ++A D D G + Y +
Sbjct: 599 NITITDVNDNQPVFFPGSYNASILEEQEIPYCFLQVNATDPDEGSAGQVTYSPSTDLVPT 658
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
FS++ + G L + LD DA + V+A+ + A RV +E D+N
Sbjct: 659 PSQFSINPLTGDLCVISRLDRDAGQE----EYNFAVKATDGGGLMSHAFVRVILE--DIN 712
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP--KGAFSIDPRS 358
DN+P F Y I + G V V+A D+D E G TY +D G F+I+ +
Sbjct: 713 DNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTIDSSTNDGTFAINQTT 772
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +T+ LD H ++V A +
Sbjct: 773 GLITLVGS--LDWVQHPVYTLEVIATD 797
Score = 57.2 bits (132), Expect = 3e-06
Identities = 120/555 (21%), Positives = 208/555 (37%), Gaps = 53/555 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ ++ T + + A D DSG+NG++ Y F + F I+ G
Sbjct: 1979 VTQDASSNTFVANVEADDKDSGVNGEVNYRFTQQ---------------SSSFAIDTVTG 2023
Query: 1000 HVIVARSLPPESEF-RLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
VI +SL P + F L + A D G+ L+ N V V+V F + Y E
Sbjct: 2024 -VITTKSLNPGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQQTYLVQPSE 2082
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-----VLSVNGELDRE 1111
A V+ + A D + ++ Y + + + F I G V++ +LD E
Sbjct: 2083 AADNGDVVLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQVQAGGSAILVVADTTKLDYE 2142
Query: 1112 TEDKYILTVVA-RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD-ELLEWKHPEADELS 1169
T+ L A R D NDN+P+F + W+ P +D
Sbjct: 2143 TQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAPQFVQDRYQSRVWEVPNSDIYV 2202
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL---ILYSLPQRKNQQN 1226
+ A E T A + T + L I S ++
Sbjct: 2203 TQVSATDADEGTNGAIYYEVTSGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARD 2262
Query: 1227 LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
G P L+ TA + + + DV D ++PVF+ + + + E++ + + ++ T+
Sbjct: 2263 GGSPQLTGTATMRIGIVDVND-----NQPVFV-QMDPVSVSEDLGVGLSVTTVTATDSDT 2316
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N ++Y + + F ID +G + L RS DRE +D Y + + A +Y+ +
Sbjct: 2317 NPNIQYSFTSTGNPG--GYFAIDQYSGIITLARSLDRETQDGYTLELEATDTEYTTTMTL 2374
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKG 1406
+ E+ D V R + P+ T N +V + G
Sbjct: 2375 EVIVTDEN--------DNAPVFRQESYQVTLPELTQPNVAVVAVNASDKDIGLNAELTYS 2426
Query: 1407 AIGHHPT---ASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINAD---IRYQI--LN 1458
+ HP+ T T++++ F + ATDS ++ +R +I +N
Sbjct: 2427 FVDSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSGAPALSEFVTVRIEITDVN 2486
Query: 1459 EQAPRFAIDPVSGTV 1473
Q+P F D S +V
Sbjct: 2487 NQSPVFVEDIYSASV 2501
Score = 49.6 bits (113), Expect = 6e-04
Identities = 101/422 (23%), Positives = 169/422 (40%), Gaps = 52/422 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE---VYIPPSKLSADALEVKRYFVINE 996
I E+ P+ TT++++ A D D GLNG++ + + I P+ +V Y +
Sbjct: 297 INESAPVNTTVLQVTASDEDEGLNGEVVFNLQRDDGFFRIDPASGIVYLNKVLNYEDA-Q 355
Query: 997 RHGHVIVA--RSLPPESEFRLNISALDGGNLNDNI-SVRVFVKDVNDHFPVFKKTWYNFN 1053
H +++A ++ PP S +S + N+N+ S+ V +F
Sbjct: 356 AHDFLVIAQDKAEPPMSSQPAYVSIMVI-NINEKPPSLEV----------LFLPDGGASQ 404
Query: 1054 VEEAQYTRRVLGKVDATDADFG--QNANLTYFIQPSDTDLPFEISPLTGVL--SVNGELD 1109
V EA L ++ TD D G N ++T DL + + ++ + D
Sbjct: 405 VSEAAVADTTLARISVTDPDDGVLTNVSMTITGGAGQFDLQKNSNQVYFLIVATTASSFD 464
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RE Y +++ A D+G DVNDN P FD L H E S
Sbjct: 465 REEVASYDISIRATDHGSPPQHAEENLTIAVT-DVNDNPP---IFD--LPLYHATIIEAS 518
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF--IGNGNGLI--LYSLPQRKN-- 1223
V + A NA I ++ + +D+ I +GL+ L + + +
Sbjct: 519 EPG-TPVKQVHATDADEGVNAQIIYRISPEGTDYSDWFEINPMSGLVTTLQKVDREETGS 577
Query: 1224 ------QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+ G SLSS+ I+ +T+ DV D ++PVF Y I E P +
Sbjct: 578 VFLTVIASDEGEISLSSSVIINITITDVND-----NQPVFFPGSYNASILEEQEIPYCFL 632
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRT---FVIDPRNGTLYLVRSPDREV-KDTYEVIV 1333
+N T+ E + + TD+ T F I+P G L ++ DR+ ++ Y V
Sbjct: 633 QVNATDPDEGSAGQ--VTYSPSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAV 690
Query: 1334 RA 1335
+A
Sbjct: 691 KA 692
Score = 44.8 bits (101), Expect = 0.018
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 10/129 (7%)
Query: 220 AIDQDLGVGATLRYELIS---GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
A+D D G L Y + N F++D V G +F D ++ AN++ V
Sbjct: 2728 ALDNDAGEYGELTYSIRGLGPSNGDDYFTIDPVTGEVFTAAVFDYES-----ANSYRFVV 2782
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
QA + Q V I +D + P F Y I + G V QV ATD D G
Sbjct: 2783 QAQDTGGLSISIQTEVNITSVD--EFPPMFNDQEYYFEIGDGADAGDYVGQVTATDADGG 2840
Query: 337 ENGEFTYQL 345
E+G Y L
Sbjct: 2841 EDGVVIYSL 2849
Score = 41.5 bits (93), Expect = 0.17
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 1425 LVFFERLSLNG-LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDA 1483
L E + +N L + ATD+D G N IRY IL EQ FA+D +GT+R + + +
Sbjct: 1453 LTLQENVGINHVLWTVSATDADSGANGLIRYTILTEQ-DFFAVDEYTGTLRTIQNVDHEI 1511
Query: 1484 GRVF 1487
VF
Sbjct: 1512 NHVF 1515
Score = 37.5 bits (83), Expect = 2.8
Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 1441 ATDSDIGINADIRYQILN-EQAPRFAIDPVSGTVRVVAALARD 1482
ATD DIG N ++ Y I++ + FAID VSG V V L R+
Sbjct: 2622 ATDRDIGYNGEVEYSIISGTYSDLFAIDVVSGAVTVRGELDRE 2664
>UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor
suppressor homolog 4; n=5; Gallus gallus|Rep: PREDICTED:
similar to FAT tumor suppressor homolog 4 - Gallus
gallus
Length = 2498
Score = 136 bits (329), Expect = 4e-30
Identities = 133/480 (27%), Positives = 219/480 (45%), Gaps = 45/480 (9%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T +++ YDE S +NV LLD NDNNP F + YE + N G I +V A D
Sbjct: 413 TARDHLSPYDEA-QSAINV--LLLDENDNNPTFTDTQ-YEQVIFINMTAGMSILQVAADD 468
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV-AESP--ILEGRH-ALFVEASDQP 542
PD G NG + + L + F+++ +TG +S+ A P + E ++ L+V A+D
Sbjct: 469 PDDGINGAISFVLAGGNE---DGYFELDKSTGQISLKAVIPLRVNESKNFVLWVTATDGG 525
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
NP + + + +R P F+ Y V + V +++
Sbjct: 526 TNPRSSSVPVHIFAVGDSR---------PQFIQKTYNVSVEEELVSPVEVARVKYESLNP 576
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
V +L E F V+ +G+I L ++ Y ++L + T
Sbjct: 577 HIPV---ILRVLTESATFDVDV-NGIIWTKIKLDFESQNNYTLN-ISLSDGVTTDYAT-V 630
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ V DVND V G + I ++ +AG ++ + T++ + + G V + +
Sbjct: 631 FIQVTDVNDNSPVF--GITNTTIKILENTAAGTSVTSVPATDVDTGF---NGLVVYTLKG 685
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ D I G I +K LDRE + +Y + VIA ++G + + +T+ I+D ND
Sbjct: 686 AEGKMD---IDASGLILLKKELDRETQGIYNLAVIAS-DQGQPRLSAVLNLTVVIDDVND 741
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFD 838
NPPVF + YE + E+ G+E+ + ATD D G NAL Y + + +F
Sbjct: 742 NPPVFSSSRYEVSVPEDKARGSELL---TVSATDLDAGANALVKYRIISQQPLTSSPVFL 798
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
V+ TG F+ LD E +++ L A D G L++ ++I + D NDN P+FNQ+
Sbjct: 799 VNLTTGQF-FLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQV 857
Score = 113 bits (272), Expect = 4e-23
Identities = 152/613 (24%), Positives = 275/613 (44%), Gaps = 66/613 (10%)
Query: 299 LNDNLPEFEVDFYNISIV--ENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
+N L +++ +N++++ E N + + ++ +D + + L G S +
Sbjct: 184 VNKTLDYNKINHFNLTVLAKERFGNNSNTVSLIIDVQDYDTLNPY-FSLSVYNGTIS-EN 241
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAK---ETNPSVVGTFADSQRIAKWRRQPLETNAP 413
+ G L++ + + ++ + + KVY P+ TF+ S A ++T
Sbjct: 242 KLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSIS---ADSGMLEVKTAVD 298
Query: 414 LEKTTYVFPD-KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN 472
E+ Y+F + + N++ D ++ VT+ D NDN PV S+ Y S+ N
Sbjct: 299 REECPYLFVGIEAAQQDNNLKTADAVVL------VTIEDVNDNLPVLSQSS-YNVSILEN 351
Query: 473 AKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT-ITSPFKINPNTGTVSVAESPILEGR 531
G + +++AVD D G Q T +LT SPF+I+ + G ++V S +L+
Sbjct: 352 FPNGKEVLRIEAVDKDEG-------GFQGTFSLTPADSPFQISQD-GILTVRNSTLLDRE 403
Query: 532 HA----LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG 587
L V A D + E + ++ V+ ++ + P F YE + N+
Sbjct: 404 QTPSIHLQVTARDHLSPYDEAQSAINVLLLD-------ENDNNPTFTDTQYEQVIFINMT 456
Query: 588 IGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLS-RYNRPMYD 644
G S+ Q+ +D + +S+ L G E+G F +++ +G I++ + R N
Sbjct: 457 AGMSILQVAADDPDDGINGAISFVLAGGNEDGY-FELDKSTGQISLKAVIPLRVNESKNF 515
Query: 645 FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
V + ++ VH+ V D R ++ ++ V+E ++
Sbjct: 516 VLWVTATDGGTNPRSSSVPVHIFAVGDSRPQFIQKTYN---VSVEEELVSPV--EVARVK 570
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
S+ + +R L + T D+ + +G I+T+ LD E ++ Y + + + GV
Sbjct: 571 YESLNPHIPVILRVL---TESATFDVDV--NGIIWTKIKLDFESQNNYTLNI--SLSDGV 623
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+ V I + D NDN PVF I+EN+ GT + + ATD D G N L
Sbjct: 624 TTDYA--TVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSV---TSVPATDVDTGFNGL 678
Query: 825 FMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELII 881
+YTL G EGK D+D +G++ + LDRE + +Y L+++A D G LS+ L +
Sbjct: 679 VVYTLKGAEGK--MDIDA-SGLI-LLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTV 734
Query: 882 MIGDENDNKPEFN 894
+I D NDN P F+
Sbjct: 735 VIDDVNDNPPVFS 747
Score = 111 bits (267), Expect = 1e-22
Identities = 94/311 (30%), Positives = 150/311 (48%), Gaps = 21/311 (6%)
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFL-----IAPIGPSLTIPLTVPRGLTIF 141
+EDVNDN P FL Y+ +V E++ ++P+ ++ L P +
Sbjct: 115 LEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGPNSDYFY 174
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE---SSHKPVLLLRKVLDYDAGDKEFQ 198
IR + D N + Y+ ++ + A E ++ V L+ V DYD + F
Sbjct: 175 --IR--EGDGNIMVNKTLDYNKINHFNLTVLAKERFGNNSNTVSLIIDVQDYDTLNPYFS 230
Query: 199 LVIM---ASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG-SLF 254
L + S ++ + PE I A D D G+ + Y + + S++ S
Sbjct: 231 LSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISADSGM 290
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
LE + +D E + + ++A+Q +N LKTA A V + + D+NDNLP YN+S
Sbjct: 291 LEVKTAVDRE---ECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLSQSSYNVS 347
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
I+EN PNG VL++ A DKD+G + T+ L F I + G LTVRN T+LDRE
Sbjct: 348 ILENFPNGKEVLRIEAVDKDEG-GFQGTFSLTPADSPFQIS-QDGILTVRNSTLLDREQT 405
Query: 375 SSLRMKVYAKE 385
S+ ++V A++
Sbjct: 406 PSIHLQVTARD 416
Score = 108 bits (259), Expect = 1e-21
Identities = 113/453 (24%), Positives = 194/453 (42%), Gaps = 26/453 (5%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + +N+ V + D NDN PVF S+ YE S+ + G+ + V A D D G N +V Y
Sbjct: 725 RLSAVLNLTVVIDDVNDNPPVF-SSSRYEVSVPEDKARGSELLTVSATDLDAGANALVKY 783
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ LT + F +N TG +++ E VE S VV I
Sbjct: 784 RIISQQPLTSSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVV-I 842
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
V + P P F Y+ V N+ G+ V V D ++ + H
Sbjct: 843 HVL--DVNDNP--PKFNQVTYDIVVFENIQKGSPVCTFSVTD---DDEAGFSQGHFIHNS 895
Query: 618 VPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERG 674
F V + G+I++ +D L R P + + A+ E L+ + + V+DVND
Sbjct: 896 TFFTV-DIPGIISLRNDTELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVNDNNP 954
Query: 675 VLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
++S + A A +G + T++ G +L + +D + I
Sbjct: 955 EFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDE--GENARITYYL--SSEDGDNPYDIQ 1010
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+DGTI +DRE ++ Y + ++A N G+ ++I + D NDN P F Y
Sbjct: 1011 QDGTILVNGCVDRETKEKYELLLVASDN-GMPRRQNFTYISIQVLDVNDNVPQFTKVHYA 1069
Query: 794 GFI-MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I + +K G + + ATD D G N++ Y+L ++F ++ +TG + +
Sbjct: 1070 ASIPVATAKEGAFVLS---VSATDLDIGNNSVISYSLMNH-SDIFHINNHTGEIILLSSL 1125
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
++ L+++A D G L+S A + + +
Sbjct: 1126 AHVTADMVVTLTVIAADHGVPPLASNASVAVCL 1158
Score = 106 bits (255), Expect = 4e-21
Identities = 121/490 (24%), Positives = 208/490 (42%), Gaps = 43/490 (8%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T NI D + V + + D NDN+PVF +N + N GT + V A D D
Sbjct: 614 TLNISLSDGVTTDYATVFIQVTDVNDNSPVFGITNT-TIKILENTAAGTSVTSVPATDVD 672
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANP 545
G NG+V+Y L+ K++ + + + + + +G + L V ASDQ
Sbjct: 673 TGFNGLVVYTLKGAEG-------KMDIDASGLILLKKELDRETQGIYNLAVIASDQ---- 721
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQ 603
+ R S AV+ + V + P P F + YE V + G+ + + DA
Sbjct: 722 GQPRLS-AVLNLTVVIDDVNDNP--PVFSSSRYEVSVPEDKARGSELLTVSATDLDAGAN 778
Query: 604 NDVSYDLL--HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVT 660
V Y ++ F V +G + L ++ E A +L+ T
Sbjct: 779 ALVKYRIISQQPLTSSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTST 838
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIF-HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
+ +HV+DVND + + ++F ++++ S G+ N F
Sbjct: 839 HVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDDEAGFSQGHFIHNSTFF 898
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIE 778
D+ I++ D LDRE + + V A + K ++ + ++ +T+
Sbjct: 899 TV---DIPGIISLRND------TELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVL-- 947
Query: 779 DENDNPPVFEHATYEGFIMENS-KIGTEIKMDNIIKATDADEGTNALFMYTLFGE-GKEM 836
D NDN P F+ +Y ++E ++G + + + ATD DEG NA Y L E G
Sbjct: 948 DVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGH-VTATDLDEGENARITYYLSSEDGDNP 1006
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
+D+ ++ G + + +DRE K Y+L LVA D G + + I + D NDN P+F
Sbjct: 1007 YDIQQD-GTI-LVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNVPQFT 1064
Query: 895 QIEENSKVRI 904
++ + + +
Sbjct: 1065 KVHYAASIPV 1074
Score = 105 bits (251), Expect = 1e-20
Identities = 128/494 (25%), Positives = 207/494 (41%), Gaps = 45/494 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F + + +LD NDN P F + + AK G + V A D D+G N ++ Y L
Sbjct: 1045 NFTYISIQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLM 1104
Query: 501 RTSNLTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPANPSERRYSLAVVTI 557
S++ F IN +TG + + S + L V A+D P S+AV +
Sbjct: 1105 NHSDI-----FHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVPPLASNASVAVCLL 1159
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
G F + YEF + + T VG ++ V Y L + +
Sbjct: 1160 VNDTGFG------LAFESSRYEFNIPEEEPVRTVVGSVKALTGSIAIQVVY-FLRSHTD- 1211
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDF--EAVALQENANLSIVTNATVHVVDVNDERGV 675
FA+ ++ ++T+ L R + +Y+ EAV N +I TV V D+ND V
Sbjct: 1212 -KFAISDQGDIVTLA-TLDREDDNLYNIVVEAVDSVVPPNTAIAL-VTVIVNDINDNPPV 1268
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AE 734
+ + + + EN A +G T++ G+ +L Q D I
Sbjct: 1269 FSELIQTKL--SLPENMAPLDLGTFSATDLD--IGDNAFISYYL---QYDFAGMFHINTS 1321
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G + T LDRE D Y + +IA + G + ++I +ED NDN PV Y
Sbjct: 1322 TGKLMTGMSLDREMMDNYELKIIA-IDSGKPPLSASLALSIAVEDVNDNSPVLSQKLYSV 1380
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ EN + ATD D G NA+ YT+ GE F V E +G + + LD
Sbjct: 1381 TVKENDPPHVILS----TTATDKDIGYNAVIQYTIIGE--TSFHVGELSGNISTV-QPLD 1433
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
E Y +L A + G L + +++ D N+ P F ++ S +I + N
Sbjct: 1434 YESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEGPMF---DKPSYFQILLD---NS 1487
Query: 913 TAGFTIIEVKPKNK 926
TAG ++++ +++
Sbjct: 1488 TAGTLVVDIDARDE 1501
Score = 98.3 bits (234), Expect = 1e-18
Identities = 113/383 (29%), Positives = 175/383 (45%), Gaps = 48/383 (12%)
Query: 1013 FRLNISALDG--GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY---TRRVLGKV 1067
F L + A+D LN + + V DVND+ P F+ Y+F V E Y V+G V
Sbjct: 922 FTLQVWAVDAEKDGLNSSSLFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHV 981
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
ATD D G+NA +TY++ D D P++I G + VNG +DRET++KY L +VA DNG
Sbjct: 982 TATDLDEGENARITYYLSSEDGDNPYDIQQ-DGTILVNGCVDRETKEKYELLLVASDNG- 1039
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE 1187
DVNDN P+F H A IPV AT +
Sbjct: 1040 MPRRQNFTYISIQVLDVNDNVPQFTKV-------HYAAS------------IPV--ATAK 1078
Query: 1188 ENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD 1247
E G V V A D D IGN N +I YSL + ++ + + IL+ ++A V
Sbjct: 1079 E----GAFVLSVSATDLD-IGN-NSVISYSLMNHSDIFHIN--NHTGEIILLSSLAHVTA 1130
Query: 1248 EVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV 1307
++ ++ V + + + N + V L+ +N T F+ Y N + + RT V
Sbjct: 1131 DMVVT-LTVIAADHGVPPLASNASVAVCLL-VNDTGFGLAFESSRYEFNIPEEEPVRTVV 1188
Query: 1308 --IDPRNGTL-----YLVRS-PDR-EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEG 1358
+ G++ Y +RS D+ + D +++ A + L +++ + V+
Sbjct: 1189 GSVKALTGSIAIQVVYFLRSHTDKFAISDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1248
Query: 1359 MTKYDVKVVVRIKDVNDNSPKFT 1381
T + V V + D+NDN P F+
Sbjct: 1249 NTAIAL-VTVIVNDINDNPPVFS 1270
Score = 85.0 bits (201), Expect = 1e-14
Identities = 151/622 (24%), Positives = 255/622 (40%), Gaps = 106/622 (17%)
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM---YTLFG 831
+ +ED NDN P F A Y + E S I + +IK D+ + LF Y+L G
Sbjct: 113 LQLEDVNDNSPEFLQALYNTSVSEVSAINS-----TVIKVEAQDKDLSPLFSHISYSLLG 167
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT-GGLSSEAELIIMIGDENDNK 890
+ F + E G + + +LD K + L+++A++ G S+ LII + D +
Sbjct: 168 PNSDYFYIREGDGNI-MVNKTLDYNKINHFNLTVLAKERFGNNSNTVSLIIDVQDYDTLN 226
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
P F+ + NGT +NK LGPL ++PE
Sbjct: 227 PYFSL------------SVYNGTIS--------ENK-------LGPLSILPE-------- 251
Query: 951 IKLNALDLDSGLNGQIRYEFN---SEVYIPPSKLSADA--LEVKRYFVINERHGHVIVAR 1005
K+ A D D+G+N ++ Y Y +SAD+ LEVK V E ++ V
Sbjct: 252 -KIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISADSGMLEVKTA-VDREECPYLFVGI 309
Query: 1006 SLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
+ N+ D V V ++DVND+ PV ++ YN ++ E + +
Sbjct: 310 EAAQQDN---NLKTADA-------VVLVTIEDVNDNLPVLSQSSYNVSILENFPNGKEVL 359
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE--LDRETEDKYILTVVAR 1123
+++A D D G T+ + P+D+ PF+IS G+L+V LDRE L V AR
Sbjct: 360 RIEAVDKDEG-GFQGTFSLTPADS--PFQISQ-DGILTVRNSTLLDREQTPSIHLQVTAR 415
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D+ D NDN+P F + ++ + ++ S++ +
Sbjct: 416 DH-LSPYDEAQSAINVLLLDENDNNPTF------TDTQYEQVIFINMTAGMSILQVAADD 468
Query: 1184 ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS--LPQRKNQ-QNLGLPSLSSTAILMV 1240
N I +A + + G I +P R N+ +N L ++
Sbjct: 469 PDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAVIPLRVNESKNFVLWVTATDGGTNP 528
Query: 1241 TVADVPDEV-EMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
+ VP + + D +P FI + Y + +EE + +PVE+ + + + +L E+
Sbjct: 529 RSSSVPVHIFAVGDSRPQFIQKTYNVSVEEELVSPVEVARVKYESLNPHIPVILRVLTES 588
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEG 1358
TF +D NG ++ D E ++ Y + + + +G
Sbjct: 589 -----ATFDVDV-NGIIWTKIKLDFESQNNYTLNI--------------------SLSDG 622
Query: 1359 MTKYDVKVVVRIKDVNDNSPKF 1380
+T V +++ DVNDNSP F
Sbjct: 623 VTTDYATVFIQVTDVNDNSPVF 644
Score = 85.0 bits (201), Expect = 1e-14
Identities = 112/456 (24%), Positives = 196/456 (42%), Gaps = 50/456 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+ + V V + D ND PVF P + FS+ N V ++GKV A+D D G N VL
Sbjct: 1763 EKKRGYCTVVVKITDVNDWPPVFNP--VTPFSVNENVDVEFIVGKVTAMDRDTGDNAFVL 1820
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP-SERRYSLA 553
Y L + F+I+ G + + SP E ++ L V A + + P + ++
Sbjct: 1821 YSLTGGGG----NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFYQATTNVT 1876
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLL 611
V+ I+V + P F Y + +G V + D + QN + Y ++
Sbjct: 1877 VLVIDV-------NDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQGQNGLIEYYII 1929
Query: 612 HGYEEGVPFAVEERS-GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
F +E+ S G I +LSR+ V ++ + S+ + A + ++V
Sbjct: 1930 PDLNFSAFFLIEDESEGKIITTGNLSRFEEVCL---TVMAKDKGSPSLNSTAVI-TLNVI 1985
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDD 729
D R + + + + + V EN+ + H+ + +G + + I + +
Sbjct: 1986 DNRPFVPRFSENKVSISVLENTG------VDHSIYTFAVAETSGKLIVYTIVSGNEKGHF 2039
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA-----GIY-----QVTIYIED 779
+ G + T L+ E +V + ++ E N+ V S A G++ +TI ++D
Sbjct: 2040 RLDPKSGQLKTAINLNYE--EVSQYVILVEANEDVSSAAQVPSSGLFAQNVAMLTITVQD 2097
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
N+ P F ++ Y I + + ++ATD D G N L Y+L +E FDV
Sbjct: 2098 VNEK-PAFLNSMYSALIPSSVPYKYPV---ITVQATDPDAGGNGLLTYSLLNH-QEQFDV 2152
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
+ENTG + + + I L L A D GGL++
Sbjct: 2153 NENTGQI-YTVSVVGYSGPIF--LGLQAADQGGLTA 2185
Score = 84.6 bits (200), Expect = 2e-14
Identities = 120/466 (25%), Positives = 197/466 (42%), Gaps = 78/466 (16%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT++ + A D+D+G NG + Y K+ DA G
Sbjct: 653 ILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGA----EGKMDIDA------------SG 696
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ + L E++ + L + A D G L+ +++ V + DVND+ PVF + Y +V
Sbjct: 697 LILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVP 756
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRET 1112
E + L V ATD D G NA + Y I QP + F ++ TG ++ +LD ET
Sbjct: 757 EDKARGSELLTVSATDLDAGANALVKYRIISQQPLTSSPVFLVNLTTGQFFLSQKLDYET 816
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
++ + + A D G DVNDN PKF D + N
Sbjct: 817 TKQFEVELEASDGG-QPSLNTSTHVVIHVLDVNDNPPKF---------NQVTYDIVVFEN 866
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQNLGL-- 1229
+ + + T ++ A G + N T F + G+I L + + + G
Sbjct: 867 IQKGSPVCTFSVTDDDEA--GFSQGHFIHNSTFFTVDIPGIISLRNDTELDRETTPGFTL 924
Query: 1230 ---------PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE---LEIEENVNAPVELV 1277
L+S+++ +TV DV D + P F + Y LE + + AP +
Sbjct: 925 QVWAVDAEKDGLNSSSLFHITVLDVND-----NNPEFQMQSYSFAVLEGDYRLGAPAVVG 979
Query: 1278 SLNLT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ T + EN ++ YY+ +E D D + I ++GT+ + DRE K+ YE+++ A
Sbjct: 980 HVTATDLDEGENARITYYLSSE-DGD--NPYDIQ-QDGTILVNGCVDRETKEKYELLLVA 1035
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
R + T ++V+ DVNDN P+FT
Sbjct: 1036 SDNGMPRR-------------QNFTYISIQVL----DVNDNVPQFT 1064
Score = 83.4 bits (197), Expect = 4e-14
Identities = 88/372 (23%), Positives = 152/372 (40%), Gaps = 26/372 (6%)
Query: 24 YRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL-VRIGAGLNQISAYLS 82
Y LN H+ VIL +S ++ ++ DF+ ++ + I + Y +
Sbjct: 571 YESLN-PHIPVILRVLTESATFDVDVNGIIWTKIKLDFESQNNYTLNISLSDGVTTDYAT 629
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT-IPLTVPRGLTIF 141
V + + DVNDN P+F T + + E T G + + + +G
Sbjct: 630 VFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGAEGK 689
Query: 142 KDIRAFD----RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
DI A + + + ++ V +D G L + +++ V D
Sbjct: 690 MDIDASGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSS 749
Query: 198 QL-VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN---DRKLFSLDSVNGSL 253
+ V + K E+L + A D D G A ++Y +IS +F ++ G
Sbjct: 750 RYEVSVPEDKARGSELL---TVSATDLDAGANALVKYRIISQQPLTSSPVFLVNLTTGQF 806
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
FL ++LD + F ++++AS P V I +LD+NDN P+F Y+I
Sbjct: 807 FLSQKLDYET-----TKQFEVELEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDI 861
Query: 314 SIVENLPNGFSVLQVMATDKDQG--ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDR 371
+ EN+ G V TD D+ G F + F++D G +++RN T LDR
Sbjct: 862 VVFENIQKGSPVCTFSVTDDDEAGFSQGHFIHN----STFFTVD-IPGIISLRNDTELDR 916
Query: 372 EAHSSLRMKVYA 383
E ++V+A
Sbjct: 917 ETTPGFTLQVWA 928
Score = 81.8 bits (193), Expect = 1e-13
Identities = 117/477 (24%), Positives = 196/477 (41%), Gaps = 49/477 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+P T I+ L A D D+G NG + Y LS D + F I+E G
Sbjct: 1689 LEENLP-ATQIVHLIARDNDTGRNGDLTYGI----------LSGDGTK----FRIDESTG 1733
Query: 1000 HVIVARSLPPE---SEFRLNISALDGGNLNDN---ISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ S E +E+++ I A D G +V V + DVND PVF F+
Sbjct: 1734 ILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVFNPVT-PFS 1792
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E ++GKV A D D G NA + Y + ++ FEI L G + + D E
Sbjct: 1793 VNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGNI-FEIDALLGNIKIKNSPDYENV 1851
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHP-EADELSN 1170
+KY LTV A +N DVNDN+P F ++ + +P ++
Sbjct: 1852 NKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHVITV 1911
Query: 1171 HNFESVM-MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
H + + + I + ++ I GN + ++ G
Sbjct: 1912 HATDKDQGQNGLIEYYIIPDLNFSAFFLIEDESEGKIITTGNLSRFEEVCLTVMAKDKGS 1971
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK 1289
PSL+STA++ + V D V P F + + EN + + + E
Sbjct: 1972 PSLNSTAVITLNVIDNRPFV-----PRFSENKVSISVLENTGVDHSIYTFAVAETSGKL- 2025
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIY 1349
+ Y I++ N+ + F +DP++G L + + E Y ++V A +
Sbjct: 2026 IVYTIVSGNE---KGHFRLDPKSGQLKTAINLNYEEVSQYVILVEANED---------VS 2073
Query: 1350 PVAEDVLEGMTKYDVKVV-VRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
A+ G+ +V ++ + ++DVN+ P F N + IP++ P+ Y V+ ++
Sbjct: 2074 SAAQVPSSGLFAQNVAMLTITVQDVNE-KPAFLNSMYSAL--IPSSVPYKYPVITVQ 2127
Score = 80.6 bits (190), Expect = 3e-13
Identities = 115/466 (24%), Positives = 200/466 (42%), Gaps = 40/466 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V V LL + + S+ YEF++ V TV+G VKA+ + V+Y
Sbjct: 1148 LASNASVAVCLLVNDTGFGLAFESSRYEFNIPEEEPVRTVVGSVKALTGSIAI--QVVYF 1205
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTI 557
L+ + T F I+ V++A + + + VEA D P+ ++A+VT+
Sbjct: 1206 LR-----SHTDKFAISDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNT---AIALVTV 1257
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVG-SNVGIGT-SVGQIRVND-AFEQNDVSYDLLHGY 614
+ N P + + + + +GT S + + D AF +SY L Y
Sbjct: 1258 -IVNDINDNPPVFSELIQTKLSLPENMAPLDLGTFSATDLDIGDNAF----ISYYL--QY 1310
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDER 673
+ F + +G + L R Y+ + +A+ LS ++ V DVND
Sbjct: 1311 DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVNDNS 1370
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
VL + +S VKEN I T+ Y +++ I + +
Sbjct: 1371 PVLSQKLYS---VTVKENDPPHVILSTTATDKDIGY---NAVIQYTIIGE----TSFHVG 1420
Query: 734 E-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E G I T +PLD E Y T+ A FN G +T+ +ED N+ P+F+ +Y
Sbjct: 1421 ELSGNISTVQPLDYESCAHYTFTLKA-FNPGEPHLQDTTNITVIVEDVNEEGPMFDKPSY 1479
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+++NS GT + +D I A D +G + Y + G + +F++ +GV+ D
Sbjct: 1480 FQILLDNSTAGT-LVVD--IDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRD 1536
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ + L++ A D+G LS+ ++ + I N + P F++
Sbjct: 1537 LNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIAPTNISLPVFSE 1582
Score = 77.4 bits (182), Expect = 3e-12
Identities = 111/477 (23%), Positives = 199/477 (41%), Gaps = 35/477 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L N+ V + D N+ P+F + ++ + N+ GT++ + A D G + +
Sbjct: 1451 EPHLQDTTNITVIVEDVNEEGPMFDKPSYFQI-LLDNSTAGTLVVDIDARDESKGYDEGI 1509
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG---RHALFVEASDQPANPSERRYSL 552
Y++ ++ + F ++ +G +++ + ++L V A+D P +
Sbjct: 1510 FYNITDGNSEGL---FNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKV 1566
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI-GTSVGQIRVNDAFEQNDVSYDLL 611
+ VTI T +P F A Y+ S + T V QI V + V Y ++
Sbjct: 1567 S-VTIAPT------NISLPVFSEAVYQPAPLSEKTLPDTFVVQITV---LYKVPVVYSIV 1616
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G E+G F + +G I L+ + F +V +++ SI + +VH V+V D
Sbjct: 1617 AGDEKGY-FIINPSTGTIRTGKKLT-VEDSLIVF-SVRATDSSTASIFNDVSVH-VEVID 1672
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
E S + ++EN QI H G++ + I + D T
Sbjct: 1673 ENDFPPVFTFSLLEQGLEENLPAT---QIVHLIARDNDTGRNGDLTYGILS-GDGTKFRI 1728
Query: 732 IAEDGTIFTQKPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
G +++ D E+ Y++ + AE + G V + I D ND PPVF
Sbjct: 1729 DESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVFNPV 1788
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
T N + E + + A D D G NA +Y+L G G +F++D G +K I
Sbjct: 1789 TP---FSVNENVDVEFIVGK-VTAMDRDTGDNAFVLYSLTGGGGNIFEIDALLGNIK-IK 1843
Query: 851 DSLDREKKIMYKLSLVA---RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
+S D E Y L++ A + + + +++ D NDN P F Q ++ + +
Sbjct: 1844 NSPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINM 1900
Score = 73.7 bits (173), Expect = 3e-11
Identities = 80/312 (25%), Positives = 128/312 (41%), Gaps = 20/312 (6%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGL 138
A ++ V + D NDN P F DT Y + G I +A P I + L
Sbjct: 424 AQSAINVLLLDENDNNPTFTDTQYEQVIFINMTAGMS--ILQVAADDPDDGINGAISFVL 481
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL-----ESSHKPVLLLRKVLDYDAG 193
+ F+ DK S + N+ +F L + P V + G
Sbjct: 482 AGGNEDGYFELDKSTGQISLKAVIPLRVNESKNFVLWVTATDGGTNPRSSSVPVHIFAVG 541
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
D Q + + +E++ P + + + + + L + F +D VNG +
Sbjct: 542 DSRPQFIQKTYNVSVEEELVSPVEVARVKYE-SLNPHIPVILRVLTESATFDVD-VNGII 599
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
+ + +LD ++++N N L++ + T A V I++ D+NDN P F + I
Sbjct: 600 WTKIKLDFESQNNYTLNI--------SLSDGVTTDYATVFIQVTDVNDNSPVFGITNTTI 651
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREA 373
I+EN G SV V ATD D G NG Y L +G ID SG + ++ + LDRE
Sbjct: 652 KILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGAEGKMDID-ASGLILLKKE--LDRET 708
Query: 374 HSSLRMKVYAKE 385
+ V A +
Sbjct: 709 QGIYNLAVIASD 720
Score = 69.7 bits (163), Expect = 6e-10
Identities = 86/329 (26%), Positives = 139/329 (42%), Gaps = 29/329 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTI 130
G ++SA L++TV I+DVNDN P+F + Y V+V E G + + G + +
Sbjct: 722 GQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALV 781
Query: 131 --------PLTV-PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
PLT P L + F K + + + +D G +L +S V
Sbjct: 782 KYRIISQQPLTSSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVV 841
Query: 182 LLLRKVLDYDAGDKEFQLVI--MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
+ VLD + +F V + + I K P ++ D G + + + +
Sbjct: 842 I---HVLDVNDNPPKFNQVTYDIVVFENIQKGS--PVCTFSVTDDDEAGFSQGHFI---H 893
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+ F++D + G + L + +LD E F LQV A + + I +LD+
Sbjct: 894 NSTFFTVD-IPGIISLRNDTELDRE---TTPGFTLQVWAVDAEKDGLNSSSLFHITVLDV 949
Query: 300 NDNLPEFEVDFYNISIVE---NLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
NDN PEF++ Y+ +++E L V V ATD D+GEN TY L G D
Sbjct: 950 NDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDI 1009
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ + N V DRE + + A +
Sbjct: 1010 QQDGTILVNGCV-DRETKEKYELLLVASD 1037
Score = 69.7 bits (163), Expect = 6e-10
Identities = 91/353 (25%), Positives = 142/353 (40%), Gaps = 35/353 (9%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGG-NLNDNIS-VRVFVKDVNDHFPVFKK 1047
F I+++ G ++ +L E + + + + A+D N I+ V V V D+ND+ PVF +
Sbjct: 1213 FAISDQ-GDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPPVFSE 1271
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
LG ATD D G NA ++Y++Q + F I+ TG L
Sbjct: 1272 LIQTKLSLPENMAPLDLGTFSATDLDIGDNAFISYYLQYDFAGM-FHINTSTGKLMTGMS 1330
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE D Y L ++A D+G DVNDNSP +L K
Sbjct: 1331 LDREMMDNYELKIIAIDSG-KPPLSASLALSIAVEDVNDNSP-------VLSQKLYSVTV 1382
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQ------ 1220
N ++ I NA I T+ +T F +G +G I P
Sbjct: 1383 KENDPPHVILSTTATDKDIGYNAVIQYTI----IGETSFHVGELSGNISTVQPLDYESCA 1438
Query: 1221 ----RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
N G P L T + V V DV +E M DKP Y+++ + +N A +
Sbjct: 1439 HYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEGPMFDKP----SYFQI-LLDNSTAGTLV 1493
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
V ++ + + + + N D + F + +G L L R +++ Y
Sbjct: 1494 VDIDARDESKGYDEGIF-YNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLY 1545
Score = 67.7 bits (158), Expect = 2e-09
Identities = 42/129 (32%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G A + Y L G +F +D++ G++ ++ D + N + L V
Sbjct: 1806 VTAMDRDTGDNAFVLYSLTGGGGN-IFEIDALLGNIKIKNSPDYE-----NVNKYTLTVT 1859
Query: 278 A-SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A + + P A V + ++D+NDN P F + Y+ SI P G V+ V ATDKDQG
Sbjct: 1860 AVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQG 1919
Query: 337 ENGEFTYQL 345
+NG Y +
Sbjct: 1920 QNGLIEYYI 1928
Score = 66.9 bits (156), Expect = 4e-09
Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 5/142 (3%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
++ + LNIS DG D +V + V DVND+ PVF T + E + V A
Sbjct: 610 QNNYTLNISLSDGVT-TDYATVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPA 668
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
TD D G N + Y ++ ++ + + S G++ + ELDRET+ Y L V+A D G
Sbjct: 669 TDVDTGFNGLVVYTLKGAEGKMDIDAS---GLILLKKELDRETQGIYNLAVIASDQG-QP 724
Query: 1130 XXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 725 RLSAVLNLTVVIDDVNDNPPVF 746
Score = 66.5 bits (155), Expect = 5e-09
Identities = 76/304 (25%), Positives = 123/304 (40%), Gaps = 33/304 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--------- 123
G ++ V +++ DVNDN P F Y + V E G F +
Sbjct: 830 GQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDDEAGFSQG 889
Query: 124 --IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
I S + +P +++ D + D+ TP + V DG L SS
Sbjct: 890 HFIHNSTFFTVDIPGIISLRNDT---ELDRETTPGFTLQVWAVDAEKDG---LNSSS--- 940
Query: 182 LLLRKVLDYDAGDKEFQL-----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
L VLD + + EFQ+ ++ R+ + + A D D G A + Y L
Sbjct: 941 LFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGH-VTATDLDEGENARITYYLS 999
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
S + + + +G++ + +D + + + L + AS P + + I++
Sbjct: 1000 SEDGDNPYDIQQ-DGTILVNGCVDRETKEKYE-----LLLVASDNGMPRRQNFTYISIQV 1053
Query: 297 LDLNDNLPEFEVDFYNISI-VENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
LD+NDN+P+F Y SI V G VL V ATD D G N +Y L + F I+
Sbjct: 1054 LDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLMNHSDIFHIN 1113
Query: 356 PRSG 359
+G
Sbjct: 1114 NHTG 1117
Score = 65.7 bits (153), Expect = 9e-09
Identities = 90/359 (25%), Positives = 154/359 (42%), Gaps = 32/359 (8%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKK 1047
F + E G++ + L ES + + A + G +L D ++ V V+DVN+ P+F K
Sbjct: 1417 FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEGPMFDK 1476
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y + + ++ +DA D G + + Y I +++ F +S +GVL++ +
Sbjct: 1477 PSYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRD 1536
Query: 1108 LDRETEDKY-ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
L+++ Y LTV A D+G N + P F E + P ++
Sbjct: 1537 LNKQAFPLYNSLTVTATDSG-LPPLSTSVKVSVTIAPTNISLP---VFSEAVYQPAPLSE 1592
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN-DTDFIGNGNGLILYSLPQRKNQQ 1225
+ F V + +YK + + G N T I G L + +
Sbjct: 1593 KTLPDTF-VVQITVLYKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTV--------ED 1643
Query: 1226 NLGLPSLSSTAILMVTV-ADVPDEVEMSDK----PVFISRYYELEIEENVNAP--VELVS 1278
+L + S+ +T ++ DV VE+ D+ PVF E +EEN+ A V L++
Sbjct: 1644 SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVFTFSLLEQGLEENLPATQIVHLIA 1703
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT-YEVIVRAE 1336
+ + N + Y IL+ + T R ID G LY S D E + T Y+V++ AE
Sbjct: 1704 RD-NDTGRNGDLTYGILSGDGTKFR----IDESTGILYSTVSFDYEEEPTEYQVVIYAE 1757
Score = 65.3 bits (152), Expect = 1e-08
Identities = 102/457 (22%), Positives = 179/457 (39%), Gaps = 39/457 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN PVF + S+ N +G A D D+G N + Y LQ
Sbjct: 1255 VTVIVNDINDNPPVFSELIQTKLSLPENM-APLDLGTFSATDLDIGDNAFISYYLQ---- 1309
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F IN +TG + S E + L + A D P +L++ +V
Sbjct: 1310 YDFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVN-- 1367
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE--EGVPF 620
N P + + Y V N + ++ D+ Y+ + Y F
Sbjct: 1368 --DNSPVLSQKL---YSVTVKEN-----DPPHVILSTTATDKDIGYNAVIQYTIIGETSF 1417
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
V E SG I+ V L + Y F A +L TN TV V DVN+E + K
Sbjct: 1418 HVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEGPMFDKP 1477
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
++ I+ + ++AG + I + S Y G N + + + + G +
Sbjct: 1478 SYFQIL--LDNSTAGTLVVDIDARDESKGYDEGIF-YNITDGNSEGLFN--LSSTSGVLT 1532
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF-IME 798
+ L+++ +Y + + G+ + +V++ I N + PVF A Y+ + E
Sbjct: 1533 LTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIAPTNISLPVFSEAVYQPAPLSE 1592
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREK 857
+ T + ++ +Y++ G+ K F ++ +TG ++ G L E
Sbjct: 1593 KTLPDTFVVQITVLYKVPV--------VYSIVAGDEKGYFIINPSTGTIR-TGKKLTVED 1643
Query: 858 K-IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
I++ + T + ++ + + + DEND P F
Sbjct: 1644 SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVF 1680
Score = 63.7 bits (148), Expect = 4e-08
Identities = 110/447 (24%), Positives = 182/447 (40%), Gaps = 42/447 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V+V V ++D ND PVF S L E ++ N ++ + A D D G+NG + Y +
Sbjct: 1664 VSVHVEVIDENDFPPVFTFS-LLEQGLEENLPATQIVHLI-ARDNDTGRNGDLTYGILSG 1721
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ F+I+ +TG + S E + + + A D +R Y VV I
Sbjct: 1722 DG----TKFRIDESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKI-- 1775
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
T N D P F V NV + VG++ D + V Y L G G
Sbjct: 1776 ---TDVN--DWPPVFNPVTPFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGG--GG 1828
Query: 618 VPFAVEERSGVITVVD--DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
F ++ G I + + D N+ AV + TN TV V+DVND V
Sbjct: 1829 NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPV 1888
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE- 734
+ ++S I + N G + + T+ G + + I + + I +
Sbjct: 1889 FAQNSYSTSINMI--NPVGVHVITVHATDKDQ---GQNGLIEYYIIPDLNFSAFFLIEDE 1943
Query: 735 -DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+G I T L R + +TV+A+ +KG S +T+ + D P F
Sbjct: 1944 SEGKIITTGNLSRFEE--VCLTVMAK-DKGSPSLNSTAVITLNVIDNRPFVPRFSENKVS 2000
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDS 852
++EN+ + D+ I E + L +YT+ G K F +D +G +K +
Sbjct: 2001 ISVLENTGV------DHSIYTFAVAETSGKLIVYTIVSGNEKGHFRLDPKSGQLK-TAIN 2053
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAEL 879
L+ E+ Y + + A + +SS A++
Sbjct: 2054 LNYEEVSQYVILVEANE--DVSSAAQV 2078
Score = 62.9 bits (146), Expect = 7e-08
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRL-NISALDGGNLN--DNIS 1030
+Y P S A + K YF+IN G + + L E + ++ A D + +++S
Sbjct: 1606 LYKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVEDSLIVFSVRATDSSTASIFNDVS 1665
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V D ND PVF + +EE +++ + A D D G+N +LTY I D
Sbjct: 1666 VHVEVIDENDFPPVFTFSLLEQGLEENLPATQIVHLI-ARDNDTGRNGDLTYGILSGD-G 1723
Query: 1091 LPFEISPLTGVLSVNGELDRETE-DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
F I TG+L D E E +Y + + A D+G DVND P
Sbjct: 1724 TKFRIDESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPP 1783
Query: 1150 KF 1151
F
Sbjct: 1784 VF 1785
Score = 61.3 bits (142), Expect = 2e-07
Identities = 49/149 (32%), Positives = 70/149 (46%), Gaps = 9/149 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D+D G G + L + S D G L + LD E Q + LQV
Sbjct: 361 IEAVDKDEG-GFQGTFSLTPADSPFQISQD---GILTVRNSTLLDRE---QTPSIHLQVT 413
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P AQ+ + + LLD NDN P F Y I N+ G S+LQV A D D G
Sbjct: 414 ARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIFINMTAGMSILQVAADDPDDGI 473
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVR 364
NG ++ L + G F +D +G ++++
Sbjct: 474 NGAISFVLAGGNEDGYFELDKSTGQISLK 502
Score = 58.8 bits (136), Expect = 1e-06
Identities = 89/378 (23%), Positives = 149/378 (39%), Gaps = 27/378 (7%)
Query: 555 VTIEVTRGTKGNKPDI----PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ---NDVS 607
+ IE+ G D+ P+F+ A Y V I ++V ++ D + +S
Sbjct: 103 IEIEIENGRDLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHIS 162
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y LL + F + E G I V L ++ +A + N S + + V
Sbjct: 163 YSLLGPNSDY--FYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGNNSNTVSLIIDVQ 220
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDV 726
D + ++ I K +IF + + I +++ +
Sbjct: 221 DYDTLNPYFSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSN 280
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
T I+ A+ G + + +DRE+ + + A + A V + IED NDN PV
Sbjct: 281 TFSIS-ADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAV-VLVTIEDVNDNLPV 338
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEGKEMFDVDENTGV 845
++Y I+EN G E+ I+A D DE G F T F + ++ +
Sbjct: 339 LSQSSYNVSILENFPNGKEVLR---IEAVDKDEGGFQGTFSLT---PADSPFQISQDGIL 392
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDNKPEFNQIEENSKVR 903
LDRE+ L + ARD EA+ + +++ DENDN P F + +
Sbjct: 393 TVRNSTLLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIF 452
Query: 904 IHRETKLNGTAGFTIIEV 921
I N TAG +I++V
Sbjct: 453 I------NMTAGMSILQV 464
Score = 56.8 bits (131), Expect = 4e-06
Identities = 78/313 (24%), Positives = 133/313 (42%), Gaps = 21/313 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-KAFIFLIAPIG 125
++ I +G +SA L++++ +EDVNDN P+ Y VTV E P + IG
Sbjct: 1343 IIAIDSGKPPLSASLALSIAVEDVNDNSPVLSQKLYSVTVKENDPPHVILSTTATDKDIG 1402
Query: 126 PSLTIPLTVPRGLTIFK--DIRA-FDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPV 181
+ I T+ G T F ++ +P S HY+ + + G L+ +
Sbjct: 1403 YNAVIQYTII-GETSFHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNIT 1461
Query: 182 LLLRKVLDYDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+++ V + DK I+ ++ I A D+ G + Y + GN
Sbjct: 1462 VIVEDVNEEGPMFDKPSYFQILLDNSTAGTLVV---DIDARDESKGYDEGIFYNITDGNS 1518
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
LF+L S +G L L ++L+ A + L V A+ P + +V + + N
Sbjct: 1519 EGLFNLSSTSGVLTLTRDLNKQAFPLYNS----LTVTATDSGLPPLSTSVKVSVTIAPTN 1574
Query: 301 DNLPEFEVDFYNISIV--ENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
+LP F Y + + + LP+ F V+Q+ K ++ D KG F I+P +
Sbjct: 1575 ISLPVFSEAVYQPAPLSEKTLPDTF-VVQITVLYK---VPVVYSIVAGDEKGYFIINPST 1630
Query: 359 GWL-TVRNQTVLD 370
G + T + TV D
Sbjct: 1631 GTIRTGKKLTVED 1643
Score = 56.4 bits (130), Expect = 6e-06
Identities = 104/399 (26%), Positives = 169/399 (42%), Gaps = 50/399 (12%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
+ A DLD G N +I Y +SE P + D ++N V R + E
Sbjct: 981 VTATDLDEGENARITYYLSSEDGDNPYDIQQDGT-----ILVNG-----CVDRETKEKYE 1030
Query: 1013 FRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKKTWY--NFNVEEAQYTRRVLGKVDA 1069
L +++ +G N + + + V DVND+ P F K Y + V A+ VL V A
Sbjct: 1031 LLL-VASDNGMPRRQNFTYISIQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVL-SVSA 1088
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI-LTVVARDNGXX 1128
TD D G N+ ++Y + + +D+ F I+ TG + + L T D + LTV+A D+G
Sbjct: 1089 TDLDIGNNSVISYSLM-NHSDI-FHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVP 1146
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
VND E+ PE + + ++ KA
Sbjct: 1147 PLASNASVAVCLL--VNDTGFGLAFESSRYEFNIPEEEPVRT-------VVGSVKAL--- 1194
Query: 1189 NAPIGTTVAKVFANDTD---FIGNGNGLILYSLPQR-KNQQNLGLPSLSS-----TAILM 1239
I V + TD G+ + L +L + N N+ + ++ S TAI +
Sbjct: 1195 TGSIAIQVVYFLRSHTDKFAISDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIAL 1254
Query: 1240 VTVADVPDEVEMSDKPVFISRYY-ELEIEENVNAPVELVSLNLT--EHYENFKMRYYILN 1296
VTV + +++ + PVF +L + EN+ AP++L + + T + +N + YY+
Sbjct: 1255 VTV--IVNDIN-DNPPVFSELIQTKLSLPENM-APLDLGTFSATDLDIGDNAFISYYL-- 1308
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
D F I+ G L S DRE+ D YE+ + A
Sbjct: 1309 --QYDFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIA 1345
Score = 53.6 bits (123), Expect = 4e-05
Identities = 98/413 (23%), Positives = 162/413 (39%), Gaps = 45/413 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P G ++++ A+D D G + F+ P ++S D + R + +R
Sbjct: 348 ILENFPNGKEVLRIEAVDKDEG---GFQGTFSLTPADSPFQISQDGILTVRNSTLLDREQ 404
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
S+ + R ++S D ++ V + D ND+ P F T Y +
Sbjct: 405 ----TPSIHLQVTARDHLSPYDEAQS----AINVLLLDENDNNPTFTDTQYEQVIFINMT 456
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD-RETEDK-YI 1117
+ +V A D D G N +++ + + D FE+ TG +S+ + R E K ++
Sbjct: 457 AGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAVIPLRVNESKNFV 516
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLEWKHPEADELSNHNFES 1175
L V A D G V D+ P+F ++ +E + E++ +ES
Sbjct: 517 LWVTATDGGTNPRSSSVPVHIFA---VGDSRPQFIQKTYNVSVEEELVSPVEVARVKYES 573
Query: 1176 V-MMIPVYKATIEENAPIGTTVAKVFAN--DTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
+ IPV + E+A V + DF N + SL G+ +
Sbjct: 574 LNPHIPVILRVLTESATFDVDVNGIIWTKIKLDFESQNNYTLNISLSD-------GVTTD 626
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK-MR 1291
+T + VT DV D + PVF ++I EN A + S+ T+ F +
Sbjct: 627 YATVFIQVT--DVND-----NSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLV 679
Query: 1292 YYILN--ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
Y L E DI +G + L + DRE + Y + V A Q R
Sbjct: 680 VYTLKGAEGKMDI-------DASGLILLKKELDRETQGIYNLAVIASDQGQPR 725
Score = 52.4 bits (120), Expect = 9e-05
Identities = 72/301 (23%), Positives = 120/301 (39%), Gaps = 18/301 (5%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYH-VTVDELT-PTGEKAFIFLIAPIGPSLT 129
+GL +S + V+V I N ++P+F + Y + E T P I ++ + +
Sbjct: 1555 SGLPPLSTSVKVSVTIAPTNISLPVFSEAVYQPAPLSEKTLPDTFVVQITVLYKVPVVYS 1614
Query: 130 IPLTVPRGLTIFKDIRAFDRD-KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
I +G I R K T + V D + S V + +V+
Sbjct: 1615 IVAGDEKGYFIINPSTGTIRTGKKLTVEDSLIVFSVRATDS---STASIFNDVSVHVEVI 1671
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI--DQDLGVGATLRYELISGNDRKLFSL 246
D + F ++ G + + + + +H I D D G L Y ++SG+ K F +
Sbjct: 1672 DENDFPPVFTFSLLEQG--LEENLPATQIVHLIARDNDTGRNGDLTYGILSGDGTK-FRI 1728
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIELLDLNDNLPE 305
D G L+ D + E + + + A P K V +++ D+ND P
Sbjct: 1729 DESTGILYSTVSFDYEEE----PTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPV 1784
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG-AFSIDPRSGWLTVR 364
F S+ EN+ F V +V A D+D G+N Y L G F ID G + ++
Sbjct: 1785 FN-PVTPFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGNIFEIDALLGNIKIK 1843
Query: 365 N 365
N
Sbjct: 1844 N 1844
Score = 52.4 bits (120), Expect = 9e-05
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 5/136 (3%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN----LQANTFVLQVQASQLNN 283
G + Y ++SGN++ F LD +G L L+ + ++AN V +
Sbjct: 2023 GKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEANEDVSSAAQVPSSG 2082
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
A + I + D+N+ P F Y+ I ++P + V+ V ATD D G NG TY
Sbjct: 2083 LFAQNVAMLTITVQDVNEK-PAFLNSMYSALIPSSVPYKYPVITVQATDPDAGGNGLLTY 2141
Query: 344 QLDDPKGAFSIDPRSG 359
L + + F ++ +G
Sbjct: 2142 SLLNHQEQFDVNENTG 2157
Score = 51.6 bits (118), Expect = 2e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 8/163 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G A + Y L + +F +++ G L LD + N + L++ A
Sbjct: 1293 ATDLDIGDNAFISYYL-QYDFAGMFHINTSTGKLMTGMSLDREMMDNYE-----LKIIAI 1346
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P +A + I + D+NDN P Y++++ EN P +L ATDKD G N
Sbjct: 1347 DSGKPPLSASLALSIAVEDVNDNSPVLSQKLYSVTVKENDP-PHVILSTTATDKDIGYNA 1405
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
Y + + +F + SG ++ + AH + +K +
Sbjct: 1406 VIQYTIIG-ETSFHVGELSGNISTVQPLDYESCAHYTFTLKAF 1447
Score = 44.8 bits (101), Expect = 0.018
Identities = 86/334 (25%), Positives = 139/334 (41%), Gaps = 38/334 (11%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--- 123
LV G+ + + +++ + DVNDNVP F Y ++ T E AF+ ++
Sbjct: 1033 LVASDNGMPRRQNFTYISIQVLDVNDNVPQFTKVHYAASIPVATAK-EGAFVLSVSATDL 1091
Query: 124 -IGPSLTIPLTVPRGLTIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
IG + I ++ IF +I T + V ++++ D G L S
Sbjct: 1092 DIGNNSVISYSLMNHSDIFHINNHTGEIILLSSLAHVTADMVVTLTVIAA-DHGVPPLAS 1150
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDL-----GVGATL 231
+ + L L D G F L +S R I EP+ + + + +
Sbjct: 1151 NASVAVCL---LVNDTG---FGLAFESS--RYEFNIPEEEPVRTVVGSVKALTGSIAIQV 1202
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
Y L S D+ F++ S G + LD + + N + + V+A P TA A
Sbjct: 1203 VYFLRSHTDK--FAI-SDQGDIVTLATLDREDD-----NLYNIVVEAVDSVVPPNTAIAL 1254
Query: 292 VEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPK 349
V + + D+NDN P F E+ +S+ EN+ + ATD D G+N +Y L D
Sbjct: 1255 VTVIVNDINDNPPVFSELIQTKLSLPENMA-PLDLGTFSATDLDIGDNAFISYYLQYDFA 1313
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
G F I+ +G L LDRE + +K+ A
Sbjct: 1314 GMFHINTSTGKLMTGMS--LDREMMDNYELKIIA 1345
Score = 44.0 bits (99), Expect = 0.032
Identities = 37/146 (25%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL--DSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+HA D+D G + Y +I + F L D G + L E L
Sbjct: 1911 VHATDKDQGQNGLIEYYIIPDLNFSAFFLIEDESEGKIITTGNLSRFEE-------VCLT 1963
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A +P + A + + ++D +P F + +IS++EN S+ A +
Sbjct: 1964 VMAKDKGSPSLNSTAVITLNVIDNRPFVPRFSENKVSISVLENTGVDHSI-YTFAVAETS 2022
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWL 361
G+ +T + KG F +DP+SG L
Sbjct: 2023 GKLIVYTIVSGNEKGHFRLDPKSGQL 2048
Score = 40.3 bits (90), Expect = 0.40
Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE-NGEFTYQLDDPKG- 350
+++L D+NDN PEF YN S+ E +V++V A DKD +Y L P
Sbjct: 112 DLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGPNSD 171
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE---TNPSVVGTFADSQ 398
F I G + V N+T LD + + V AKE N + V D Q
Sbjct: 172 YFYIREGDGNIMV-NKT-LDYNKINHFNLTVLAKERFGNNSNTVSLIIDVQ 220
Score = 36.3 bits (80), Expect = 6.5
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
A +VTV + DVNDN P+F Y +++ + P G
Sbjct: 1871 ATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVG 1905
>UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenopus
tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
Length = 2787
Score = 136 bits (329), Expect = 4e-30
Identities = 218/938 (23%), Positives = 376/938 (40%), Gaps = 116/938 (12%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L S ++++ L D NDN PVF + ++N G+ I +++A D D G N V+Y
Sbjct: 747 ELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLP-GSSIYRIQAFDFDSGNNAKVVY 805
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLA 553
+ + SPF IN TG V L+ H L + A D NP R A
Sbjct: 806 SILMSD----PSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDG-GNPV--RTGTA 858
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
++ I +T IP F Y+ + ++ I T+V Q+ D E ++Y L+
Sbjct: 859 LIRIAIT----DVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLI 914
Query: 612 HGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQ---ENANLSIVTNATVH 665
+ + F++ SG I +L+ + Y+ A + N A +
Sbjct: 915 RTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLR 974
Query: 666 VV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIAN 722
++ D ND V + + I S A I ++ +GT G++ + +
Sbjct: 975 IIVTDYNDNVPVFTQQVYKISI------SESAPINSTVTVVTATDKDDGTNGHITYSFSR 1028
Query: 723 QQDVTDDIAIAE----DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ + +G I T++ D E+ +++ ++A+ N G + + I+I
Sbjct: 1029 TAENAFHTQMFNINPANGEIKTKRSFDYEQHKEFQINIMAKDN-GSPPLSSNATLIIHII 1087
Query: 779 DENDNPPVFEHATYEG----FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
D+NDN P + + E F + + I A+D D G NA +Y++
Sbjct: 1088 DQNDNAPKILYPSTESGGSPFFEMVPFASVQGSLITKIHASDPDAGDNAKIIYSISNINT 1147
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
E F V S++ E ++Y A+ + E + I +++ P
Sbjct: 1148 EDFPVSPYF--------SINIETGVLY-----AQRSFDYEQHKEFQMKISAKDNGSPP-- 1192
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
+ N + IH IIE+ +N A ++ PE+ GT I +
Sbjct: 1193 -LSSNVTLIIH------------IIEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIE 1239
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
D DSG NG++ + I PS + + Y ++N + R L P +
Sbjct: 1240 VHDQDSGENGEVECQI-----IGPSPFQLLSSSSRYYKIVNTGS----LDRELVPW--YN 1288
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
+ I A D G+ L+ +++ + DVND+ P+F K+ + + E + + A+D
Sbjct: 1289 ITILATDRGSPQLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPENNLPGASIYSIHASDP 1348
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXX 1129
D+G NA + Y I +PF++ TG + LDRE Y +T+VA D G
Sbjct: 1349 DYGNNAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYNITIVATDKG-SP 1407
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEEN 1189
DVNDN P F ++ PE +N S+ I +N
Sbjct: 1408 QLSSRKFIRLDISDVNDNPPVFMKSKDVAYL--PE----NNLPGSSIYRIQASDLDTGDN 1461
Query: 1190 APIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ---------QNLGLPSLSSTAILMV 1240
A + +++ + D + L+L R+ Q + G P S TA++ +
Sbjct: 1462 AKVIYSISSMDNEDFPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRI 1521
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNEN 1298
V D D + PVF Y++ I EN+ ++++N T+ E N ++ Y +
Sbjct: 1522 AVTDSNDNL-----PVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFRSS- 1575
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
F I+ G LY RS D E +++ V A+
Sbjct: 1576 ------FFSINIETGVLYAQRSFDYEQHKEFQIKVYAK 1607
Score = 132 bits (320), Expect = 5e-29
Identities = 127/489 (25%), Positives = 224/489 (45%), Gaps = 47/489 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + DANDN PVF + +Y+ S+ N + + + V A D D G N + Y +TS
Sbjct: 1945 IRIIVTDANDNLPVFTKA-VYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSE 2003
Query: 505 LTITSP-FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
I SP F IN G + + E + + V+A+D + + ++++
Sbjct: 2004 NDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGG------FVAKSILLDIS- 2056
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP 619
+ P P F+ + Y ++ N G S+ +++ +D E + V Y + + E P
Sbjct: 2057 -DVNDNP--PVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAFP 2113
Query: 620 ----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDER 673
F++ +GV+ + A ++N S+ +NAT + ++D ND
Sbjct: 2114 VSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQA-KDNGYPSLSSNATLIIRIIDQNDNA 2172
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIAI 732
I++ ENS + + + G+ +V+ + +++ Q T +
Sbjct: 2173 --------PKILYPSTENSDSLIFEMVPFASTAEDPDIGSNSVQTYKLSDNQYFTLNEKT 2224
Query: 733 AEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ DG+ F + +PLDRE ++++ + + A + G G + + + D NDN PVF
Sbjct: 2225 SSDGSKFPELVLERPLDRETKNIHELLLTAS-DGGTPVRTGTALIRVIVTDANDNTPVFT 2283
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD-ENTGVVK 847
Y+ I EN+ I + + + A+D DEGTNA Y+ F + F VD EN + +
Sbjct: 2284 QEVYKVSISENTPINSTVLR---VNASDMDEGTNAQITYS-FSRTSKYFSVDLENGNLYE 2339
Query: 848 FIGD-SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
+ + LDRE K +++L L A D G + A + +++ D NDN P F Q E KV I
Sbjct: 2340 LVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ--EVYKVSI 2397
Query: 905 HRETKLNGT 913
T +N T
Sbjct: 2398 SENTPINST 2406
Score = 126 bits (304), Expect = 5e-27
Identities = 120/462 (25%), Positives = 208/462 (45%), Gaps = 31/462 (6%)
Query: 447 VTLLDANDNNPVFVPSNLY----EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
VT++D NDN P ++L E + N G+ I V A D D GQN + Y L+
Sbjct: 220 VTVVDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSG 279
Query: 503 S-NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S N T + K + N ++ + ++ E V + P + ++ T +
Sbjct: 280 SGNQTYSLNSKFS-NYYSLVLKDNLDRES-----VAEYNVPISATDNGIPALSTTAYIYF 333
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP 619
+ P F Y F + N+ G+ + Q+ +D + + + Y LL Y EG+
Sbjct: 334 SVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMS 393
Query: 620 ----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDER 673
++ SG + VD P + V + ++ + T T V V D+ND
Sbjct: 394 VSHFISINPDSGNVFSVDSFDYEKIPQKNI-TVTVTDSGTPPLSTQKTLYVEVSDLNDNP 452
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ ++S I+ ++ N+ G ++ + T++ S N V + + D
Sbjct: 453 PTFEEKSYS--IYIMENNAPGVSLISVKATDLDS---NENSFVSYSLLRASDPKLFQVEL 507
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I T LDRE Y +T+++ ++G + + + + I D NDN P+F+ +TY
Sbjct: 508 HTGEIRTTSFLDRENTSQYNITILST-DRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYV 566
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDS 852
++ EN+ G+ I I A D D G NA +Y++ G K FD++ +G + D
Sbjct: 567 AYLSENNLPGSSIYR---INAYDPDTGDNAKIIYSIAGTNIKSTFDINPTSGKITTKRD- 622
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
LD E Y++++ A D GG ++ +++I I DENDN PE +
Sbjct: 623 LDFESVQSYEIAIEAMDGGGFVAQTKVLIEIIDENDNAPEIS 664
Score = 126 bits (303), Expect = 6e-27
Identities = 133/480 (27%), Positives = 214/480 (44%), Gaps = 41/480 (8%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNP-VFVPSNLY---EFSMKSNA-KVGTVIGKVKAVDP 487
+Y L ++ + + D NDN P + PS+ F M A + G +I KV AVD
Sbjct: 1608 DYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDA 1667
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPAN 544
D G N + Y + + S ++ F I+ NTG + ++ P+ + H L + ASD N
Sbjct: 1668 DSGHNAWLSYHVVQGSEPSL---FSISQNTGEIRTSQKPLDRETQTIHELILTASDG-GN 1723
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVG---SNVGIGTSVGQIRVND-- 599
P R A++ I VT ++P F Y+ + + GT + I V+D
Sbjct: 1724 PV--RSGTALIRIAVTDAND----NLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQD 1777
Query: 600 AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSI 658
+ E ++ LL + + + +IT L R P Y+ A + +LS
Sbjct: 1778 SGENGEIDCQLLGTGPFQLLLSSTKYYRIITT-GSLDREKVPWYNITIQATDRGSPHLSN 1836
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+ + + DVND V K ++ + + + N AGA+I +I S I + +
Sbjct: 1837 IKLIKLDISDVNDNAPVFTKSSY--VAYIAENNLAGASIYRI---QASDIDAGDNAKIIY 1891
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
I N + I+ +QKPLDRE + + + + A + G + I +
Sbjct: 1892 SIYNTEPSPFSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVK-TGTAIIRIIVT 1950
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--- 835
D NDN PVF A Y+ I EN I + + N ATD DEGTNA Y+ +
Sbjct: 1951 DANDNLPVFTKAVYKVSISENIPINSSVLHVN---ATDRDEGTNAQITYSFIKTSENDIH 2007
Query: 836 --MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
MF +++ G +K + LD E Y++S+ A D GG +++ +++ I D NDN P F
Sbjct: 2008 SPMFSINQINGEIKTL-QKLDFELTRNYEMSVQATDGGGFVAKS-ILLDISDVNDNPPVF 2065
Score = 119 bits (287), Expect = 5e-25
Identities = 171/699 (24%), Positives = 288/699 (41%), Gaps = 67/699 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + D+NDN PVF +Y+ S+ N + + + V A D D G N ++Y +
Sbjct: 1519 IRIAVTDSNDNLPVFT-QEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFR---- 1573
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALF---VEASDQPANPSERRYSLAVVTIEVTR 561
+S F IN TG + S E +H F V A D +PS A +TI +T
Sbjct: 1574 ---SSFFSINIETGVLYAQRSFDYE-QHKEFQIKVYAKDY-GSPSLS--CNASLTIRIT- 1625
Query: 562 GTKGNKPDI--PDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEE 616
N P I P F V G + ++ DA ++ +SY ++ G E
Sbjct: 1626 DQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEP 1685
Query: 617 GVPFAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERG 674
+ F++ + +G I T L R + +++ A N S + V D ND
Sbjct: 1686 SL-FSISQNTGEIRTSQKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLP 1744
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
V + + I + E+S + + + NG + + L + ++ +
Sbjct: 1745 VFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLGTGPFQLL--LSSTK 1802
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
I T LDREK Y +T+ A ++G + I + + I D NDN PVF ++Y
Sbjct: 1803 YYRIITTGSLDREKVPWYNITIQAT-DRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVA 1861
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+I EN+ G I I+A+D D G NA +Y+++ F + ++TG ++ LD
Sbjct: 1862 YIAENNLAGASIYR---IQASDIDAGDNAKIIYSIYNTEPSPFSISQHTGEIRSSQKPLD 1918
Query: 855 REKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ------IEEN-----SK 901
RE + ++L L A D G + A + I++ D NDN P F + I EN S
Sbjct: 1919 RETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSV 1978
Query: 902 VRIHRETKLNGT-AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
+ ++ + GT A T +K D P+F I + I I L LD +
Sbjct: 1979 LHVNATDRDEGTNAQITYSFIKTSEN-----DIHSPMFSINQ---INGEIKTLQKLDFEL 2030
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRY--FVINERHGHVIVARSLPPESEFRLNIS 1018
N ++ + + D +V + R+ + +LP S +++ S
Sbjct: 2031 TRNYEMSVQATDGGGFVAKSILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQAS 2090
Query: 1019 ALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE-AQYTRRVLGKVDATDADFGQN 1077
LD G N + VF + + FPV ++++ N+E Y +R D+ Q+
Sbjct: 2091 DLDTGE-NSKVIYSVFNTN-TEAFPV--SSYFSINIETGVLYAQR--------SFDYEQH 2138
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+Q D P S T ++ + + D + Y
Sbjct: 2139 KEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILY 2177
Score = 117 bits (282), Expect = 2e-24
Identities = 132/498 (26%), Positives = 227/498 (45%), Gaps = 43/498 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ + D NDN PVF S +Y+ S+ NA GT++ K+ A D D+G+NG Y+ +
Sbjct: 112 INVEDVNDNPPVFNQS-VYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPER 170
Query: 507 ITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ S F ++ TG V V E + + ++A D + L V ++V
Sbjct: 171 MLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDV----N 226
Query: 565 GNKPDIP-DFMGAPY-EFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDLLHGYEEGVPF 620
N P++ + P E N G+ + + +D+ QN ++Y L G
Sbjct: 227 DNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYS 286
Query: 621 AVEERSGVITVV--DDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVL 676
+ S ++V D+L R + Y+ ++ +N ++ T A ++ V D+ND +
Sbjct: 287 LNSKFSNYYSLVLKDNLDRESVAEYNV-PISATDNGIPALSTTAYIYFSVDDINDNPPLF 345
Query: 677 LKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ---QDVTDDIAI 732
+ + F + EN G+ I Q+ ++ S G + L+ + V+ I+I
Sbjct: 346 TEELY---FFSIAENILPGSLIFQVSASDKDS--GKNAQLLYALLESYVEGMSVSHFISI 400
Query: 733 AED-GTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIE--DENDNPPVFE 788
D G +F+ D EK +TV + + +S Q T+Y+E D NDNPP FE
Sbjct: 401 NPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLS----TQKTLYVEVSDLNDNPPTFE 456
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
+Y +IMEN+ G + +KATD D N+ Y+L ++F V+ +TG ++
Sbjct: 457 EKSYSIYIMENNAPGVSLIS---VKATDLDSNENSFVSYSLLRASDPKLFQVELHTGEIR 513
Query: 848 FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
LDRE Y +++++ D G LS+ + + I D NDN P F ++++ V
Sbjct: 514 -TTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIF---KKSTYVAYL 569
Query: 906 RETKLNGTAGFTIIEVKP 923
E L G++ + I P
Sbjct: 570 SENNLPGSSIYRINAYDP 587
Score = 116 bits (279), Expect = 5e-24
Identities = 128/485 (26%), Positives = 206/485 (42%), Gaps = 58/485 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + DANDN PVF +Y+ S+ N + + + +V A D D G N + Y RTS
Sbjct: 2268 IRVIVTDANDNTPVFT-QEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSK 2326
Query: 505 LTITSPFKINPNTGTVS--VAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
F ++ G + V E P+ ++ H L + ASD + R A++ + V
Sbjct: 2327 Y-----FSVDLENGNLYELVLERPLDREIKNIHELLLTASD---GGTPVRTGTALIRVIV 2378
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG 617
T P F Y+ + N I ++V ++ +D E + ++Y E
Sbjct: 2379 TDANDNT----PVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENS 2434
Query: 618 VP---FAVEERSGVIT--VVDDLSRY-----NRPMYDFEAVALQE------NANLSIVTN 661
+ F++ SG + D S++ RP+ D E + E + + T
Sbjct: 2435 LHASMFSINPTSGEMNEKTSSDGSKFPELVLERPL-DRETKNIHELLLTASDGGTPVRTG 2493
Query: 662 AT---VHVVDVNDERGVLLKGAHSPIIF-HVKENSAGAAIGQIFH---TNMSSIYGNGTG 714
V V D ND V + + I + NS + TN Y
Sbjct: 2494 TALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRT 2553
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+V L A+ + G I T L+ E + Y ++V A+ G ++ + ++ V
Sbjct: 2554 SVNSLHASMFSINPT-----SGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVI 2608
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----- 829
I I+D NDN P F Y I EN+ +G+ + + ATD DEG NA Y+
Sbjct: 2609 IEIQDINDNAPKFFPVLYTVSISENTAVGSVVL---CVNATDKDEGINAQITYSFSKTSE 2665
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDN 889
K MF ++ TG +K L+ E Y+LS+ A+D GG + ++++I I DENDN
Sbjct: 2666 SSLNKSMFSINPTTGEIK-TEKQLNFEGTRNYELSVQAKDGGGFVTHSKVLIEITDENDN 2724
Query: 890 KPEFN 894
PE +
Sbjct: 2725 APEIS 2729
Score = 115 bits (277), Expect = 9e-24
Identities = 128/505 (25%), Positives = 222/505 (43%), Gaps = 45/505 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + ++ + + D NDN P+F S + ++N G+ I ++ A DPD G N ++Y
Sbjct: 539 KLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLP-GSSIYRINAYDPDTGDNAKIIY 597
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVV 555
+ T+ I S F INP +G ++ E + + +EA D ++ + V
Sbjct: 598 SIAGTN---IKSTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTK-----V 649
Query: 556 TIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLH 612
IE+ N P+I + AP + + GT + I+V+ D +V +L
Sbjct: 650 LIEII-DENDNAPEISIASLSAP----IPEDSMPGTVIALIKVHDQDTGRNGEVDCQILG 704
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
+ + +IT L R P Y+ +A + + LS + + + DVND
Sbjct: 705 AAPFQIVSSSSRYYRIIT-ASFLDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVND 763
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
V K + + + + N G++I +I + S GN V ++ +
Sbjct: 764 NPPVFSKPTY--VAYLPENNLPGSSIYRIQAFDFDS--GNNAKVVYSILMSDPSPFSINQ 819
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ + KPLDRE ++++ + A F+ G G + I I D ND+ P+F
Sbjct: 820 YTGEHKVVIMKPLDRENLKIHKLLLTA-FDGGNPVRTGTALIRIAITDVNDHIPMFTQEV 878
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GE--GKEMFDVDENTGVV 846
Y+ I E+ I T + + ATD DEG NA Y+L G+ F ++ +G +
Sbjct: 879 YKVSISESIPINTTVLQ---VNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEI 935
Query: 847 KFIGDSLDREKKIMYKLSLVARD---TGG---LSSEAELIIMIGDENDNKPEFNQIEENS 900
K +L+ E + Y++S+ A+D GG + A L I++ D NDN P F Q +
Sbjct: 936 K-TKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVFTQ--QVY 992
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKN 925
K+ I +N T T++ K+
Sbjct: 993 KISISESAPINSTV--TVVTATDKD 1015
Score = 107 bits (258), Expect = 2e-21
Identities = 115/428 (26%), Positives = 190/428 (44%), Gaps = 67/428 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENIPI ++++ +NA D D G N QI Y F K S + + F IN+ +G
Sbjct: 1968 ISENIPINSSVLHVNATDRDEGTNAQITYSF--------IKTSENDIH-SPMFSINQING 2018
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E + +++ A DGG S+ + + DVND+ PVF K+ Y + E
Sbjct: 2019 EIKTLQKLDFELTRNYEMSVQATDGGGFVAK-SILLDISDVNDNPPVFLKSRYIAYLPEN 2077
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP----FEISPLTGVLSVNGELDRET 1112
+ KV A+D D G+N+ + Y + ++T+ P F I+ TGVL D E
Sbjct: 2078 NLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQ 2137
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
++ + V A+DNG D NDN+PK +P + +
Sbjct: 2138 HKEFAMHVQAKDNG-YPSLSSNATLIIRIIDQNDNAPKIL---------YPSTENSDSLI 2187
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVF-ANDTDFI---------GNGNGLILYSLPQRK 1222
FE M+P A+ E+ IG+ + + +D + G+ ++ P +
Sbjct: 2188 FE---MVPF--ASTAEDPDIGSNSVQTYKLSDNQYFTLNEKTSSDGSKFPELVLERPLDR 2242
Query: 1223 NQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--V 1270
+N+ G P + TA++ V V D D + PVF Y++ I EN +
Sbjct: 2243 ETKNIHELLLTASDGGTPVRTGTALIRVIVTDAND-----NTPVFTQEVYKVSISENTPI 2297
Query: 1271 NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY---LVRSPDREVKD 1327
N+ V V+ + + N ++ Y + + F +D NG LY L R DRE+K+
Sbjct: 2298 NSTVLRVNASDMDEGTNAQITYSFSRTS-----KYFSVDLENGNLYELVLERPLDREIKN 2352
Query: 1328 TYEVIVRA 1335
+E+++ A
Sbjct: 2353 IHELLLTA 2360
Score = 103 bits (248), Expect = 3e-20
Identities = 119/484 (24%), Positives = 212/484 (43%), Gaps = 41/484 (8%)
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
F K+ K + +++ + ++D NDN P +L ++ GT+I
Sbjct: 1179 FQMKISAKDNGSPPLSSNVTLIIHI-IEIMDENDNAPEISIRSL-STPFPEDSAPGTLIA 1236
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSP----FKINPNTGTVSVAESPILEGRHALFV 536
++ D D G+NG V + S + S +KI NTG++ P + + +
Sbjct: 1237 LIEVHDQDSGENGEVECQIIGPSPFQLLSSSSRYYKI-VNTGSLDRELVPW----YNITI 1291
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
A+D+ S + ++ + ++++ + P P F+ + + ++ N G S+ I
Sbjct: 1292 LATDRG---SPQLSTMKFIKLDIS--DVNDNP--PMFVKSTFVAYLPENNLPGASIYSIH 1344
Query: 597 VNDAFEQNDVSYDLLHGYEEG-VPFAVEERSGV---ITVVDDLSRYNRPMYDFEAVALQE 652
+D N+ G VPF ++ +G I L R +Y+ VA +
Sbjct: 1345 ASDPDYGNNAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYNITIVATDK 1404
Query: 653 NA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN 711
+ LS + + DVND V +K S + ++ EN+ + I+ S +
Sbjct: 1405 GSPQLSSRKFIRLDISDVNDNPPVFMK---SKDVAYLPENNLPGS--SIYRIQASDLDTG 1459
Query: 712 GTGNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
V + I++ + +D I+ + +KPLDRE + ++ + + A + +G
Sbjct: 1460 DNAKVIYSISSMDN--EDFPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVR-SGT 1516
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+ I + D NDN PVF Y+ I EN I + + + ATD DEGTNA MY+
Sbjct: 1517 ALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVL---TVNATDRDEGTNAQIMYSF- 1572
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEND 888
F ++ TGV+ + S D E+ +++ + A+D G LS A L I I D+ND
Sbjct: 1573 --RSSFFSINIETGVL-YAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQND 1629
Query: 889 NKPE 892
N P+
Sbjct: 1630 NVPK 1633
Score = 102 bits (245), Expect = 7e-20
Identities = 126/495 (25%), Positives = 206/495 (41%), Gaps = 40/495 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL S + + + D NDN PVF+ S + ++N G+ I +++A D D G N V+Y
Sbjct: 1408 QLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLP-GSSIYRIQASDLDTGDNAKVIY 1466
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAV 554
+ N F I+ + V E P+ + H L + ASD NP R A+
Sbjct: 1467 SISSMDN----EDFPISSYFSKL-VLEKPLDRETQTIHELILTASD-GGNPV--RSGTAL 1518
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+ I VT + ++P F Y+ + N+ I ++V + VN + +++ +
Sbjct: 1519 IRIAVT----DSNDNLPVFTQEVYKVSISENIPINSTV--LTVNATDRDEGTNAQIMYSF 1572
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
F++ +GV+ + + A + +LS + T+ + D ND
Sbjct: 1573 RSSF-FSINIETGVLYAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQNDNV 1631
Query: 674 GVLL----KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
+L + S + GA I ++ + S G+ ++ +
Sbjct: 1632 PKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADS--GHNAWLSYHVVQGSEPSLFS 1689
Query: 730 IAIAEDGTIFT-QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I+ G I T QKPLDRE + ++ + + A + G +G + I + D NDN PVF
Sbjct: 1690 IS-QNTGEIRTSQKPLDRETQTIHELILTAS-DGGNPVRSGTALIRIAVTDANDNLPVFT 1747
Query: 789 HATYE---GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
Y+ I E+S GT I +I+ D D G N L G G +
Sbjct: 1748 QEVYKVSITIIPEDSPSGTLIA---LIEVHDQDSGENGEIDCQLLGTGPFQLLLSSTKYY 1804
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
SLDREK Y +++ A D G LS+ + + I D NDN P F ++S V
Sbjct: 1805 RIITTGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFT---KSSYVA 1861
Query: 904 IHRETKLNGTAGFTI 918
E L G + + I
Sbjct: 1862 YIAENNLAGASIYRI 1876
Score = 102 bits (244), Expect = 9e-20
Identities = 70/226 (30%), Positives = 112/226 (49%), Gaps = 13/226 (5%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFN--SEVYIPPSKLSADALEVK---RYFVI 994
I EN PI +T++++NA D+D G N QI Y F+ SE + S S + + +
Sbjct: 2397 ISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSD 2456
Query: 995 NERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWY 1050
+ +++ R L E++ L ++A DGG +RV V D ND+ PVF + Y
Sbjct: 2457 GSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVY 2516
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEISPLTGVLSVNG 1106
++ E + +V+A+D D G NA +TY F + S L F I+P +G ++ N
Sbjct: 2517 KVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNN 2576
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
L+ E + Y ++V A+D G D+NDN+PKF+
Sbjct: 2577 LLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFF 2622
Score = 98.7 bits (235), Expect = 1e-18
Identities = 82/288 (28%), Positives = 134/288 (46%), Gaps = 20/288 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G A + Y IS D + F + S L LEK LD + + L +
Sbjct: 1451 IQASDLDTGDNAKVIYS-ISSMDNEDFPISSYFSKLVLEKPLDRETQ-----TIHELILT 1504
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS NP+++ A + I + D NDNLP F + Y +SI EN+P +VL V ATD+D+G
Sbjct: 1505 ASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGT 1564
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFAD 396
N + Y FSI+ +G L Q D E H ++KVYAK+ +PS+ +
Sbjct: 1565 NAQIMYSF--RSSFFSINIETGVLYA--QRSFDYEQHKEFQIKVYAKDYGSPSLSCNASL 1620
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+ RI + N + K Y + V + E + EQ + +V +DA+ +
Sbjct: 1621 TIRIT-------DQNDNVPKILYPSSESVDSSFEMVPVASEQ--GALITKVVAVDADSGH 1671
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++ ++ + S S + G+++ L + +++L T++
Sbjct: 1672 NAWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTAS 1719
Score = 94.7 bits (225), Expect = 2e-17
Identities = 119/422 (28%), Positives = 185/422 (43%), Gaps = 52/422 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P GT + KL A D+D G NG+ YEF+ +P LS F +++ G
Sbjct: 133 ITENAPKGTLVAKLFATDMDVGKNGETSYEFSK--LVPERMLSL--------FSLDKYTG 182
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV- 1054
V V L E + + I ALD G L + + V V DVND+ P T + V
Sbjct: 183 EVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEMTVTSLSLPVP 242
Query: 1055 EEAQYTRRVLGK----VDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSV--NGE 1107
E+A + G V A+D+D GQN+ +TY ++ + + + S + S+
Sbjct: 243 EDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSKFSNYYSLVLKDN 302
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA---FDELLEWKHPE 1164
LDRE+ +Y + + A DNG D+NDN P F F + E P
Sbjct: 303 LDRESVAEYNVPISATDNGIPALSTTAYIYFSVD-DINDNPPLFTEELYFFSIAENILPG 361
Query: 1165 A--DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK 1222
+ ++S + +S + A +E G +V+ + + D +GN + S K
Sbjct: 362 SLIFQVSASDKDSGKNAQLLYALLESYVE-GMSVSHFISINPD---SGNVFSVDSFDYEK 417
Query: 1223 -NQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP- 1273
Q+N+ G P LS+ L V V+D+ D + P F + Y + I EN NAP
Sbjct: 418 IPQKNITVTVTDSGTPPLSTQKTLYVEVSDLND-----NPPTFEEKSYSIYIMEN-NAPG 471
Query: 1274 VELVSLNLT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
V L+S+ T + EN + Y +L +D + F ++ G + DRE Y +
Sbjct: 472 VSLISVKATDLDSNENSFVSYSLLRASDP---KLFQVELHTGEIRTTSFLDRENTSQYNI 528
Query: 1332 IV 1333
+
Sbjct: 529 TI 530
Score = 94.3 bits (224), Expect = 2e-17
Identities = 118/497 (23%), Positives = 200/497 (40%), Gaps = 44/497 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + + D NDN PVF+ S + ++N G I KV+A D D G+N V+Y + T+
Sbjct: 2050 SILLDISDVNDNPPVFLKSRYIAYLPENNLP-GASIYKVQASDLDTGENSKVIYSVFNTN 2108
Query: 504 N--LTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEV 559
++S F IN TG + S E A+ V+A D +L + I+
Sbjct: 2109 TEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQ 2168
Query: 560 T-RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
K P + +E ++ +G V ++ +D Y L+
Sbjct: 2169 NDNAPKILYPSTENSDSLIFEMVPFASTAEDPDIGSNSVQ-TYKLSDNQYFTLNEKTSSD 2227
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT-VHVVDVNDERGVLL 677
E + + L R + +++ A + T V V D ND V
Sbjct: 2228 GSKFPE----LVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFT 2283
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD-DIAIAEDG 736
+ + + EN+ + N S + + + + D+
Sbjct: 2284 QEVYK---VSISENTP--INSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVDLENGNLY 2338
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ ++PLDRE ++++ + + A + G G + + + D NDN PVF Y+ I
Sbjct: 2339 ELVLERPLDREIKNIHELLLTAS-DGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSI 2397
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFDVDENTGVV----- 846
EN+ I + + + A+D DEGTNA Y+ + MF ++ +G +
Sbjct: 2398 SENTPINSTVLR---VNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTS 2454
Query: 847 ----KF----IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQI 896
KF + LDRE K +++L L A D G + A + +++ D NDN P F Q
Sbjct: 2455 SDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ- 2513
Query: 897 EENSKVRIHRETKLNGT 913
E KV I T +N T
Sbjct: 2514 -EVYKVSISENTPINST 2529
Score = 94.3 bits (224), Expect = 2e-17
Identities = 69/220 (31%), Positives = 107/220 (48%), Gaps = 21/220 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN PI +T++++NA D+D G N QI Y F S+ S ++L F IN G
Sbjct: 2520 ISENTPINSTVLRVNASDMDEGTNAQITYSF--------SRTSVNSLHASM-FSINPTSG 2570
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNL---NDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ L E+ ++ +++ A DGG + V + ++D+ND+ P F Y ++
Sbjct: 2571 EITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSI 2630
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEISPLTGVLSVNGELDR 1110
E V+ V+ATD D G NA +TY F + S++ L F I+P TG + +L+
Sbjct: 2631 SENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLNF 2690
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
E Y L+V A+D G D NDN+P+
Sbjct: 2691 EGTRNYELSVQAKDGG---GFVTHSKVLIEITDENDNAPE 2727
Score = 92.3 bits (219), Expect = 9e-17
Identities = 125/500 (25%), Positives = 207/500 (41%), Gaps = 44/500 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V+V + D NDN PVF PS+ Y S+ + GT AVD D+G N + Y+L
Sbjct: 1 VDVEIEDINDNYPVF-PSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNYELSANDY 59
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLAVVTIEVTR 561
T+ P I V + + + H L + A D P + ++ +E
Sbjct: 60 FTLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFD-GGKPKLSGSTQLIINVE--- 115
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGV- 618
+ P P F + Y+ + N GT V ++ D + + SY+ E +
Sbjct: 116 -DVNDNP--PVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERML 172
Query: 619 -PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
F++++ +G + V +L Y+ AL + L+ V VVDVND +
Sbjct: 173 SLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEM 232
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI------ANQQDVTDDI 730
+ + V E++ H S + TG F+ + Q + +
Sbjct: 233 ---TVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNS 289
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ ++ + LDRE Y + + A N G+ + + + ++D NDNPP+F
Sbjct: 290 KFSNYYSLVLKDNLDRESVAEYNVPISATDN-GIPALSTTAYIYFSVDDINDNPPLFTEE 348
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEG---KEMFDVDENTG 844
Y I EN G+ I + A+D D G NA +Y L + EG ++ ++G
Sbjct: 349 LYFFSIAENILPGSLIFQ---VSASDKDSGKNAQLLYALLESYVEGMSVSHFISINPDSG 405
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
V F DS D EK +++ D+G LS++ L + + D NDN P F E++ +
Sbjct: 406 NV-FSVDSFDYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFE--EKSYSI 462
Query: 903 RIHRETKLNGTAGFTIIEVK 922
I N G ++I VK
Sbjct: 463 YIME----NNAPGVSLISVK 478
Score = 90.6 bits (215), Expect = 3e-16
Identities = 106/411 (25%), Positives = 177/411 (43%), Gaps = 44/411 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ GT A+D D G N YE ++ Y LE+ + F+ +
Sbjct: 24 VPESRLPGTRFPLEGAVDADIGTNSITNYELSANDYF--------TLELPK-FIYQIKSI 74
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ +SL E S L + A DGG L+ + + + V+DVND+ PVF ++ Y ++
Sbjct: 75 QLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQLIINVEDVNDNPPVFNQSVYQCSIT 134
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY---FIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
E ++ K+ ATD D G+N +Y + P F + TG + V GELD E
Sbjct: 135 ENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEK 194
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE-ADELSNH 1171
+ Y + + A DNG DVNDN+P+ L PE A +N
Sbjct: 195 SNTYEVLIDALDNG-EHLLTGHCQLLVTVVDVNDNAPEMTVTS--LSLPVPEDATHENNP 251
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN-------Q 1224
+ + + +N+ I ++ N T + N YSL + N +
Sbjct: 252 PGSHIYTVSASDSDTGQNSFITYSLRSGSGNQT-YSLNSKFSNYYSLVLKDNLDRESVAE 310
Query: 1225 QNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVE 1275
N+ G+P+LS+TA + +V D+ D + P+F Y I EN+ + +
Sbjct: 311 YNVPISATDNGIPALSTTAYIYFSVDDIND-----NPPLFTEELYFFSIAENILPGSLIF 365
Query: 1276 LVSLNLTEHYENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
VS + + +N ++ Y +L + I+P +G ++ V S D E
Sbjct: 366 QVSASDKDSGKNAQLLYALLESYVEGMSVSHFISINPDSGNVFSVDSFDYE 416
Score = 88.6 bits (210), Expect = 1e-15
Identities = 114/486 (23%), Positives = 201/486 (41%), Gaps = 50/486 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK-AVDPDLGQNGMVLY 497
L S + + ++D NDN P LY + S++ + ++ A DPD+G N + Y
Sbjct: 2155 LSSNATLIIRIIDQNDN----APKILYPSTENSDSLIFEMVPFASTAEDPDIGSNSVQTY 2210
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAV 554
L T+ + + V E P+ + H L + ASD + R A+
Sbjct: 2211 KLSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASD---GGTPVRTGTAL 2267
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+ + VT + P F Y+ + N I ++V +RVN + + + + +
Sbjct: 2268 IRVIVTDA----NDNTPVFTQEVYKVSISENTPINSTV--LRVNASDMDEGTNAQITYSF 2321
Query: 615 EE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT----VHVVDV 669
F+V+ +G + + +R + + + L + + V T V V D
Sbjct: 2322 SRTSKYFSVDLENGNLYELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDA 2381
Query: 670 NDERGVLLK-------GAHSPI---IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
ND V + ++PI + V + + S N F
Sbjct: 2382 NDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFS 2441
Query: 720 IANQQDVTDDIAIAEDGTIF----TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
I N + + DG+ F ++PLDRE ++++ + + A + G G + +
Sbjct: 2442 I-NPTSGEMNEKTSSDGSKFPELVLERPLDRETKNIHELLLTAS-DGGTPVRTGTALIRV 2499
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-- 833
+ D NDN PVF Y+ I EN+ I + + + A+D DEGTNA Y+
Sbjct: 2500 IVTDANDNTPVFTQEVYKVSISENTPINSTVLR---VNASDMDEGTNAQITYSFSRTSVN 2556
Query: 834 ---KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE---LIIMIGDEN 887
MF ++ +G + + L+ E K Y++S+ A+D GG + ++ +II I D N
Sbjct: 2557 SLHASMFSINPTSGEIT-TNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDIN 2615
Query: 888 DNKPEF 893
DN P+F
Sbjct: 2616 DNAPKF 2621
Score = 87.8 bits (208), Expect = 2e-15
Identities = 85/333 (25%), Positives = 149/333 (44%), Gaps = 26/333 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-----KAFIFLI---API 124
G ++S+ S+ + + DVNDN P+F Y + E G +AF F A +
Sbjct: 744 GSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKV 803
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
S+ + P + + KP + N +H +++ D G+ + +
Sbjct: 804 VYSILMSDPSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIA 863
Query: 184 LRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
+ V D+ +E V ++ I+ +L ++A D+D GV A + Y LI +
Sbjct: 864 ITDVNDHIPMFTQEVYKVSISESIPINTTVL---QVNATDKDEGVNAQITYSLIRTSGDS 920
Query: 243 L----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
L FS++ +G + ++ L+ + + + + + A+ NP +T A + I + D
Sbjct: 921 LASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKD-GATDGGNPKRTGTALLRIIVTD 979
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGA-----F 352
NDN+P F Y ISI E+ P +V V ATDKD G NG TY + A F
Sbjct: 980 YNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMF 1039
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+I+P +G ++ + D E H ++ + AK+
Sbjct: 1040 NINPANG--EIKTKRSFDYEQHKEFQINIMAKD 1070
Score = 86.6 bits (205), Expect = 5e-15
Identities = 124/457 (27%), Positives = 194/457 (42%), Gaps = 55/457 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPE+ P GT I + D DSG NG+I + + P +L L +Y+
Sbjct: 1757 IIPEDSPSGTLIALIEVHDQDSGENGEIDCQL---LGTGPFQL---LLSSTKYY------ 1804
Query: 999 GHVIVARSLPPESE--FRLNISALDGGNLN-DNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
+I SL E + + I A D G+ + NI +++ + DVND+ PVF K+ Y +
Sbjct: 1805 -RIITTGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYI 1863
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-VLSVNGELDRETE 1113
E + ++ A+D D G NA + Y I ++ PF IS TG + S LDRET+
Sbjct: 1864 AENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPS-PFSISQHTGEIRSSQKPLDRETQ 1922
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+ L + A D G D NDN P F +K ++ + ++
Sbjct: 1923 KDHELILTASDGG-DPVKTGTAIIRIIVTDANDNLPVF----TKAVYKVSISENIPINS- 1976
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD----FIGNGNGLI--LYSLPQRKNQQNL 1227
SV+ + NA I + K ND I NG I L L + +N
Sbjct: 1977 -SVLHVNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKL-DFELTRNY 2034
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDK-PVFI-SRYYELEIEENV-NAPVELVSLNLTEH 1284
+ ++ V + + D +++D PVF+ SRY E N+ A + V + +
Sbjct: 2035 EMSVQATDGGGFVAKSILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDT 2094
Query: 1285 YENFKMRYYILNENDT--DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
EN K+ Y + N N + F I+ G LY RS D E + + V+A+ Y
Sbjct: 2095 GENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGY-- 2152
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
P + + +++RI D NDN+PK
Sbjct: 2153 --PSL-------------SSNATLIIRIIDQNDNAPK 2174
Score = 85.0 bits (201), Expect = 1e-14
Identities = 152/682 (22%), Positives = 273/682 (40%), Gaps = 78/682 (11%)
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDN-----------PPVFEHATYEGFIMENSK 801
+ + +A + ++GA IY++ D DN P F + + G I + K
Sbjct: 1856 KSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPSPFSISQHTGEIRSSQK 1915
Query: 802 -IGTEIKMDNIIKATDADEG----TNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
+ E + D+ + T +D G T + + + + V I +++
Sbjct: 1916 PLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPIN 1975
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
+++ ++ RD G + I + + + P F+ + N +++ ++ T +
Sbjct: 1976 SSVLH-VNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNY 2034
Query: 917 TI-IEVKPKNKFAL--------DVDQLGPLFL-------IPENIPIGTTIIKLNALDLDS 960
+ ++ F DV+ P+FL +PEN G +I K+ A DLD+
Sbjct: 2035 EMSVQATDGGGFVAKSILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDT 2094
Query: 961 GLNGQIRYE-FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNI 1017
G N ++ Y FN+ + +A V YF IN G + RS E EF +++
Sbjct: 2095 GENSKVIYSVFNT---------NTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHV 2145
Query: 1018 SALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
A D G +L+ N ++ + + D ND+ P K + + ++ V A D D G
Sbjct: 2146 QAKDNGYPSLSSNATLIIRIIDQNDNAP--KILYPSTENSDSLIFEMVPFASTAEDPDIG 2203
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGV----LSVNGELDRETEDKYILTVVARDNGXXXXX 1131
N+ TY + + E + G L + LDRET++ + L + A D G
Sbjct: 2204 SNSVQTYKLSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRT 2263
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
D NDN+P F E+ + E + N V + + T +
Sbjct: 2264 GTALIRVIVT-DANDNTPVFT--QEVYKVSISENTPI-NSTVLRVNASDMDEGTNAQITY 2319
Query: 1192 IGTTVAKVFANDTDFIGNGNGLILYSLPQR--KNQQNL-------GLPSLSSTAILMVTV 1242
+ +K F+ D + GN L+L R KN L G P + TA++ V V
Sbjct: 2320 SFSRTSKYFSVDLEN-GNLYELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIV 2378
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDT 1300
D D PVF Y++ I EN +N+ V V+ + + N ++ Y ++
Sbjct: 2379 TDANDNT-----PVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSEN 2433
Query: 1301 DIRRT-FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
+ + F I+P +G + S D E+++ + ++ + H + A D +
Sbjct: 2434 SLHASMFSINPTSGEMNEKTSSDGSKFP--ELVLERPLDRETKNI-HELLLTASDGGTPV 2490
Query: 1360 TKYDVKVVVRIKDVNDNSPKFT 1381
+ V + D NDN+P FT
Sbjct: 2491 RTGTALIRVIVTDANDNTPVFT 2512
Score = 85.0 bits (201), Expect = 1e-14
Identities = 87/338 (25%), Positives = 146/338 (43%), Gaps = 46/338 (13%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGLTI 140
+ V + D NDN P+F Y V++ E TP + + G + I + R
Sbjct: 2268 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKY 2327
Query: 141 FK------DIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
F ++ ++P + ++H +++ +D G + + L +V+ DA
Sbjct: 2328 FSVDLENGNLYELVLERPLDREIKNIHELLLTASDGG-----TPVRTGTALIRVIVTDAN 2382
Query: 194 D------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL---- 243
D +E V ++ I+ +L ++A D D G A + Y ++ L
Sbjct: 2383 DNTPVFTQEVYKVSISENTPINSTVL---RVNASDMDEGTNAQITYSFSRTSENSLHASM 2439
Query: 244 FSLD----------SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
FS++ S +GS F E L+ + + N L + AS P++T A +
Sbjct: 2440 FSINPTSGEMNEKTSSDGSKFPELVLERPLDRETK-NIHELLLTASDGGTPVRTGTALIR 2498
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK---- 349
+ + D NDN P F + Y +SI EN P +VL+V A+D D+G N + TY
Sbjct: 2499 VIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL 2558
Query: 350 --GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
FSI+P SG +T N +L+ EA + V AK+
Sbjct: 2559 HASMFSINPTSGEITTNN--LLNFEAKKDYEISVQAKD 2594
Score = 84.6 bits (200), Expect = 2e-14
Identities = 106/433 (24%), Positives = 181/433 (41%), Gaps = 51/433 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS- 503
+ V + DANDN PVF +Y+ S+ N + + + +V A D D G N + Y RTS
Sbjct: 2374 IRVIVTDANDNTPVFT-QEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSE 2432
Query: 504 NLTITSPFKINPNTGTVS-------------VAESPI---LEGRHALFVEASDQPANPSE 547
N S F INP +G ++ V E P+ + H L + ASD +
Sbjct: 2433 NSLHASMFSINPTSGEMNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASD---GGTP 2489
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-- 605
R A++ + VT + P F Y+ + N I ++V ++ +D E +
Sbjct: 2490 VRTGTALIRVIVTDA----NDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQ 2545
Query: 606 VSYDLLHGYEEGV---PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL--SIVT 660
++Y + F++ SG IT + L+ + Y+ A + S V
Sbjct: 2546 ITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVF 2605
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIF--HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+ + D+ND P+++ + EN+A ++ + N F
Sbjct: 2606 PVIIEIQDINDNAPKFF-----PVLYTVSISENTAVGSVVLCVNATDKDEGINAQITYSF 2660
Query: 719 LIANQQDVTDDIAIAE--DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
++ + + G I T+K L+ E Y ++V A+ G ++ + +V I
Sbjct: 2661 SKTSESSLNKSMFSINPTTGEIKTEKQLNFEGTRNYELSVQAKDGGGFVTHS---KVLIE 2717
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
I DENDN P A+ + E+S G+ I +I+ D D G+NA Y++ E M
Sbjct: 2718 ITDENDNAPEISIASLSTPVPEDSAPGSVIA---LIEVHDQDSGSNAKITYSI-SETNTM 2773
Query: 837 ---FDVDENTGVV 846
F ++ TGV+
Sbjct: 2774 SPYFSINIETGVL 2786
Score = 83.8 bits (198), Expect = 3e-14
Identities = 104/434 (23%), Positives = 184/434 (42%), Gaps = 58/434 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN PI +T++++NA D+D G N QI Y F+ +YF ++ +G
Sbjct: 2291 ISENTPINSTVLRVNASDMDEGTNAQITYSFS---------------RTSKYFSVDLENG 2335
Query: 1000 HV---IVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
++ ++ R L E + L ++A DGG +RV V D ND+ PVF + Y
Sbjct: 2336 NLYELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 2395
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDL---PFEISPLTGVL----SV 1104
++ E + +V+A+D D G NA +TY F + S+ L F I+P +G + S
Sbjct: 2396 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSS 2455
Query: 1105 NGE----------LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--Y 1152
+G LDRET++ + L + A D G D NDN+P F
Sbjct: 2456 DGSKFPELVLERPLDRETKNIHELLLTASDGG-TPVRTGTALIRVIVTDANDNTPVFTQE 2514
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIE-ENAPIGTTVAKVFA-NDTDFIGNG 1210
+ + P + N + + T + + A +F+ N T
Sbjct: 2515 VYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITT 2574
Query: 1211 NGLILYSLPQR-----KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
N L+ + + + + G + S +++ + D+ D + P F Y +
Sbjct: 2575 NNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDIND-----NAPKFFPVLYTVS 2629
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRT-FVIDPRNGTLYLVRSPD 1322
I EN ++ +N T+ E N ++ Y +++ + ++ F I+P G + + +
Sbjct: 2630 ISENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLN 2689
Query: 1323 REVKDTYEVIVRAE 1336
E YE+ V+A+
Sbjct: 2690 FEGTRNYELSVQAK 2703
Score = 83.0 bits (196), Expect = 6e-14
Identities = 65/219 (29%), Positives = 103/219 (47%), Gaps = 15/219 (6%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F I ENI G+ I +++A D DSG N Q+ Y E Y+ + + V + IN
Sbjct: 352 FSIAENILPGSLIFQVSASDKDSGKNAQLLYAL-LESYV-------EGMSVSHFISINPD 403
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G+V S E + + ++ D G L+ ++ V V D+ND+ P F++ Y+
Sbjct: 404 SGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSYSIY 463
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E L V ATD D +N+ ++Y ++ SD L F++ TG + LDRE
Sbjct: 464 IMENNAPGVSLISVKATDLDSNENSFVSYSLLRASDPKL-FQVELHTGEIRTTSFLDREN 522
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +T+++ D G DVNDN+P F
Sbjct: 523 TSQYNITILSTDRG-SPKLSTVKHIRLNISDVNDNAPIF 560
Score = 81.4 bits (192), Expect = 2e-13
Identities = 87/337 (25%), Positives = 146/337 (43%), Gaps = 32/337 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFI--FLIAPIGP-SLT---------I 130
V V IED+NDN P+F + Y ++V E G + + + A IG S+T
Sbjct: 1 VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNYELSANDYF 60
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
L +P+ + K I+ + + VH + D G L S + L+ V D
Sbjct: 61 TLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQ---LIINVEDV 117
Query: 191 DAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE---LISGNDRKLFSL 246
+ F Q V S + + A D D+G YE L+ LFSL
Sbjct: 118 NDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSLFSL 177
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D G ++++ ELD + ++NT+ + + A L T ++ + ++D+NDN PE
Sbjct: 178 DKYTGEVWVKGELDYE-----KSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEM 232
Query: 307 EVDFYNISIV-----ENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPR-S 358
V ++ + EN P G + V A+D D G+N TY L G +S++ + S
Sbjct: 233 TVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSKFS 292
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
+ ++ + LDRE+ + + + A + + T A
Sbjct: 293 NYYSLVLKDNLDRESVAEYNVPISATDNGIPALSTTA 329
Score = 81.4 bits (192), Expect = 2e-13
Identities = 81/306 (26%), Positives = 128/306 (41%), Gaps = 21/306 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELT--------------PTGEKAFIFLIAPIGPS 127
S+ + I DVNDN P+FL + Y + E TGE + + +
Sbjct: 2050 SILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNT 2109
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
P++ + I + R + + V D+G+ +L S+ L++R +
Sbjct: 2110 EAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMH-VQAKDNGYPSLSSN--ATLIIRII 2166
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D K S I + + F A D D+G + Y+L L
Sbjct: 2167 DQNDNAPKILYPSTENSDSLIFEMVPFAST--AEDPDIGSNSVQTYKLSDNQYFTLNEKT 2224
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
S +GS F E L+ + + N L + AS P++T A + + + D NDN P F
Sbjct: 2225 SSDGSKFPELVLERPLDRETK-NIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFT 2283
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL-TVRNQ 366
+ Y +SI EN P +VL+V A+D D+G N + TY FS+D +G L + +
Sbjct: 2284 QEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVDLENGNLYELVLE 2343
Query: 367 TVLDRE 372
LDRE
Sbjct: 2344 RPLDRE 2349
Score = 79.8 bits (188), Expect = 5e-13
Identities = 103/420 (24%), Positives = 175/420 (41%), Gaps = 52/420 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+L N+P G++I ++NA D D+G N +I Y S +K F IN
Sbjct: 568 YLSENNLP-GSSIYRINAYDPDTGDNAKIIY-------------SIAGTNIKSTFDINPT 613
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G + R L ES + + I A+DGG V + + D ND+ P + +
Sbjct: 614 SGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIP 673
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI---SPLTGVLSVNGELDRET 1112
E V+ + D D G+N + I + PF+I S + LDRE
Sbjct: 674 EDSMPGTVIALIKVHDQDTGRNGEVDCQILGA---APFQIVSSSSRYYRIITASFLDREK 730
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
Y +T++A D G DVNDN P F + PE +N
Sbjct: 731 VPWYNITILATDKG-SPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYL--PE----NNLP 783
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN---GNGLILYSLP-QRKNQQ--- 1225
S+ I + NA + ++ + ++ + F N G ++ P R+N +
Sbjct: 784 GSSIYRIQAFDFDSGNNAKVVYSI--LMSDPSPFSINQYTGEHKVVIMKPLDRENLKIHK 841
Query: 1226 ------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+ G P + TA++ + + DV D + P+F Y++ I E++ ++ +
Sbjct: 842 LLLTAFDGGNPVRTGTALIRIAITDVNDHI-----PMFTQEVYKVSISESIPINTTVLQV 896
Query: 1280 NLTEHYE--NFKMRYYIL-NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
N T+ E N ++ Y ++ D+ TF I+P +G + R+ + EV+ YE+ V A+
Sbjct: 897 NATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAK 956
Score = 78.6 bits (185), Expect = 1e-12
Identities = 112/467 (23%), Positives = 191/467 (40%), Gaps = 68/467 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN G++I ++ A DLD+G N ++ Y +S + + + YF
Sbjct: 1438 LPENNLPGSSIYRIQASDLDTGDNAKVIYSISS--------MDNEDFPISSYF------S 1483
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ + L E++ L ++A DGGN + +R+ V D ND+ PVF + Y ++
Sbjct: 1484 KLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSIS 1543
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + V+ATD D G NA + Y + S F I+ TGVL D E +
Sbjct: 1544 ENIPINSTVLTVNATDRDEGTNAQIMYSFRSSF----FSINIETGVLYAQRSFDYEQHKE 1599
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK-FYAFDELLEWKHPEADELSNHNFE 1174
+ + V A+D G D NDN PK Y E ++ E +++
Sbjct: 1600 FQIKVYAKDYG-SPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSF-EMVPVASEQGA 1657
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS-LPQRKNQQNL------ 1227
+ + A NA + V + I G I S P + Q +
Sbjct: 1658 LITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILT 1717
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEI----EENVNAP-VELVS 1278
G P S TA++ + V D D + PVF Y++ I E++ + + L+
Sbjct: 1718 ASDGGNPVRSGTALIRIAVTDANDNL-----PVFTQEVYKVSITIIPEDSPSGTLIALIE 1772
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
++ + EN ++ +L T + + + + S DRE Y + ++A
Sbjct: 1773 VHDQDSGENGEIDCQLLG---TGPFQLLLSSTKYYRIITTGSLDREKVPWYNITIQAT-- 1827
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVV-VRIKDVNDNSPKFTNGN 1384
R PH+ ++K++ + I DVNDN+P FT +
Sbjct: 1828 --DRGSPHL--------------SNIKLIKLDISDVNDNAPVFTKSS 1858
Score = 75.8 bits (178), Expect = 9e-12
Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 12/166 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN +G+ ++ +NA D D G+N QI Y F SK S +L K F IN G
Sbjct: 2630 ISENTAVGSVVLCVNATDKDEGINAQITYSF--------SKTSESSLN-KSMFSINPTTG 2680
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E + L++ A DGG + V + + D ND+ P + V E
Sbjct: 2681 EIKTEKQLNFEGTRNYELSVQAKDGGGFVTHSKVLIEITDENDNAPEISIASLSTPVPED 2740
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVL 1102
V+ ++ D D G NA +TY I ++T P F I+ TGVL
Sbjct: 2741 SAPGSVIALIEVHDQDSGSNAKITYSISETNTMSPYFSINIETGVL 2786
Score = 75.4 bits (177), Expect = 1e-11
Identities = 106/418 (25%), Positives = 175/418 (41%), Gaps = 52/418 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G+ I ++A D D+G N I Y S L++ + Y+ +
Sbjct: 248 ENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNS---KFSNYYSL------- 297
Query: 1002 IVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++ +L ES E+ + ISA D G L+ + V D+ND+ P+F + Y F++ E
Sbjct: 298 VLKDNLDRESVAEYNVPISATDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAEN 357
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-----FIQPSDTDLPFEISPLTG-VLSVNGELDRE 1111
++ +V A+D D G+NA L Y +++ I+P +G V SV+ D E
Sbjct: 358 ILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHFISINPDSGNVFSVDS-FDYE 416
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
+ +TV D+G D+NDN P F E K + N
Sbjct: 417 KIPQKNITVTVTDSGTPPLSTQKTLYVEVS-DLNDNPPTF-------EEKSYSIYIMEN- 467
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG---NGNGLILYSLPQRKN--QQN 1226
N V +I V ++ N + + + A+D + + S R+N Q N
Sbjct: 468 NAPGVSLISVKATDLDSNENSFVSYSLLRASDPKLFQVELHTGEIRTTSFLDRENTSQYN 527
Query: 1227 L-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+ G P LS+ + + ++DV D P+F Y + EN + +
Sbjct: 528 ITILSTDRGSPKLSTVKHIRLNISDVNDNA-----PIFKKSTYVAYLSENNLPGSSIYRI 582
Query: 1280 NL--TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N + +N K+ Y I T+I+ TF I+P +G + R D E +YE+ + A
Sbjct: 583 NAYDPDTGDNAKIIYSIAG---TNIKSTFDINPTSGKITTKRDLDFESVQSYEIAIEA 637
Score = 74.9 bits (176), Expect = 2e-11
Identities = 58/218 (26%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
++++ N P G ++I + A DLDS N + Y S L A + F +
Sbjct: 462 IYIMENNAP-GVSLISVKATDLDSNENSFVSY----------SLLRASD---PKLFQVEL 507
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
G + L E S++ + I + D G+ L+ +R+ + DVND+ P+FKK+ Y
Sbjct: 508 HTGEIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVA 567
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E + +++A D D G NA + Y I ++ F+I+P +G ++ +LD E+
Sbjct: 568 YLSENNLPGSSIYRINAYDPDTGDNAKIIYSIAGTNIKSTFDINPTSGKITTKRDLDFES 627
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y + + A D G D NDN+P+
Sbjct: 628 VQSYEIAIEAMDGG---GFVAQTKVLIEIIDENDNAPE 662
Score = 74.5 bits (175), Expect = 2e-11
Identities = 73/294 (24%), Positives = 129/294 (43%), Gaps = 18/294 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLI-API 124
L+ G ++S + + +EDVNDN P+F + Y ++ E P G A +F +
Sbjct: 94 LMAFDGGKPKLSGSTQLIINVEDVNDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDV 153
Query: 125 GP----SLTIPLTVP-RGLTIFKDIR----AFDRDKPNTPNSDVHYSIVSGNDDGHFALE 175
G S VP R L++F + + + + + S+ + ++ D+G L
Sbjct: 154 GKNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLT 213
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLR 232
+ ++ + V D L + H+ I+ + D D G + +
Sbjct: 214 GHCQLLVTVVDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFIT 273
Query: 233 YELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
Y L SG+ + +SL+S + + L + +LD E + N + + A+ P + A
Sbjct: 274 YSLRSGSGNQTYSLNSKFSNYYSLVLKDNLDRESVAEYN---VPISATDNGIPALSTTAY 330
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ + D+NDN P F + Y SI EN+ G + QV A+DKD G+N + Y L
Sbjct: 331 IYFSVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYAL 384
Score = 73.3 bits (172), Expect = 5e-11
Identities = 50/156 (32%), Positives = 79/156 (50%), Gaps = 14/156 (8%)
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
D F++V +AS + L + + A+D D G A L Y ++ G++ LFS+ G +
Sbjct: 1643 DSSFEMVPVAS----EQGALITKVV-AVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEI 1697
Query: 254 FL-EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+K LD + + L + AS NP+++ A + I + D NDNLP F + Y
Sbjct: 1698 RTSQKPLDRETQ-----TIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYK 1752
Query: 313 ISIV---ENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+SI E+ P+G + + D+D GENGE QL
Sbjct: 1753 VSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQL 1788
Score = 72.9 bits (171), Expect = 6e-11
Identities = 57/175 (32%), Positives = 84/175 (48%), Gaps = 15/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL-FLEKELDLDAEHNLQANTFVLQV 276
I A D D G A + Y + + + FS+ G + +K LD + + + + L +
Sbjct: 1876 IQASDIDAGDNAKIIYSIYN-TEPSPFSISQHTGEIRSSQKPLDRETQKDHE-----LIL 1929
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS +P+KT A + I + D NDNLP F Y +SI EN+P SVL V ATD+D+G
Sbjct: 1930 TASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEG 1989
Query: 337 ENGEFTYQL------DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + TY D FSI+ +G ++ LD E + M V A +
Sbjct: 1990 TNAQITYSFIKTSENDIHSPMFSINQING--EIKTLQKLDFELTRNYEMSVQATD 2042
Score = 70.9 bits (166), Expect = 2e-10
Identities = 62/212 (29%), Positives = 98/212 (46%), Gaps = 21/212 (9%)
Query: 218 IHAIDQDLGVGATLRYELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D+D G A L Y L+ + S++ +G++F D E Q N
Sbjct: 367 VSASDKDSGKNAQLLYALLESYVEGMSVSHFISINPDSGNVFSVDSFDY--EKIPQKN-- 422
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ V + P + Q + +E+ DLNDN P FE Y+I I+EN G S++ V ATD
Sbjct: 423 -ITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSYSIYIMENNAPGVSLISVKATD 481
Query: 333 KDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D EN +Y L DPK F ++ +G +R + LDRE S + + + +
Sbjct: 482 LDSNENSFVSYSLLRASDPK-LFQVELHTG--EIRTTSFLDRENTSQYNITILSTDRGSP 538
Query: 390 VVGTFADSQRIAKWRRQPLETNAPL-EKTTYV 420
+ T + + + NAP+ +K+TYV
Sbjct: 539 KLSTV----KHIRLNISDVNDNAPIFKKSTYV 566
Score = 69.7 bits (163), Expect = 6e-10
Identities = 67/254 (26%), Positives = 114/254 (44%), Gaps = 21/254 (8%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
++A D D G A + Y ++ +FS++ +G + L+ +A+ + +
Sbjct: 2533 VNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYE----- 2587
Query: 274 LQVQASQLNNPLKTAQA-RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ VQA + ++ V IE+ D+NDN P+F Y +SI EN G VL V ATD
Sbjct: 2588 ISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENTAVGSVVLCVNATD 2647
Query: 333 KDQGENGEFTYQLDDP------KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
KD+G N + TY K FSI+P +G ++ + L+ E + + V AK+
Sbjct: 2648 KDEGINAQITYSFSKTSESSLNKSMFSINPTTG--EIKTEKQLNFEGTRNYELSVQAKDG 2705
Query: 387 NPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKV-GTKTENIEYYDEQLMSFVNV 445
V + + + P + A L +T V D G+ IE +D+ S +
Sbjct: 2706 GGFVTHSKVLIEITDENDNAPEISIASL--STPVPEDSAPGSVIALIEVHDQDSGSNAKI 2763
Query: 446 EVTLLDANDNNPVF 459
++ + N +P F
Sbjct: 2764 TYSISETNTMSPYF 2777
Score = 67.3 bits (157), Expect = 3e-09
Identities = 48/178 (26%), Positives = 82/178 (46%), Gaps = 9/178 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D + + Y L+ +D KLF ++ G + LD E+ Q N +L
Sbjct: 477 VKATDLDSNENSFVSYSLLRASDPKLFQVELHTGEI--RTTSFLDRENTSQYNITIL--- 531
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++ +P + + + + D+NDN P F+ Y + EN G S+ ++ A D D G+
Sbjct: 532 STDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGD 591
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
N + Y + + K F I+P SG +T + LD E+ S + + A + V T
Sbjct: 592 NAKIIYSIAGTNIKSTFDINPTSGKITTKRD--LDFESVQSYEIAIEAMDGGGFVAQT 647
Score = 66.9 bits (156), Expect = 4e-09
Identities = 67/240 (27%), Positives = 103/240 (42%), Gaps = 21/240 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+IE+ +N A ++ IPE+ GT I + D D+G NG++ +
Sbjct: 650 LIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQI------- 702
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRV 1033
L A ++ + R+ +I A L E + + I A D G+ L+ S+++
Sbjct: 703 ---LGAAPFQI---VSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKL 756
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
+ DVND+ PVF K Y + E + ++ A D D G NA + Y I SD PF
Sbjct: 757 DLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILMSDPS-PF 815
Query: 1094 EISPLTG--VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I+ TG + + LDRE + L + A D G DVND+ P F
Sbjct: 816 SINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGG-NPVRTGTALIRIAITDVNDHIPMF 874
Score = 66.9 bits (156), Expect = 4e-09
Identities = 87/345 (25%), Positives = 145/345 (42%), Gaps = 46/345 (13%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS----- 127
G +S + + I DVNDN P+F + Y + E G + + I
Sbjct: 1830 GSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKI 1889
Query: 128 -LTIPLTVPRGLTIFK---DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+I T P +I + +IR+ + D H I++ +D G K
Sbjct: 1890 IYSIYNTEPSPFSISQHTGEIRSSQKPLDRETQKD-HELILTASDGG-----DPVKTGTA 1943
Query: 184 LRKVLDYDAGD------KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI- 236
+ +++ DA D K V ++ I+ +L ++A D+D G A + Y I
Sbjct: 1944 IIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLH---VNATDRDEGTNAQITYSFIK 2000
Query: 237 -SGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
S ND +FS++ +NG + ++LD + N + + VQA+ + + +
Sbjct: 2001 TSENDIHSPMFSINQINGEIKTLQKLDFELTRNYE-----MSVQATDGGGFVAKS---IL 2052
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP----- 348
+++ D+NDN P F Y + EN G S+ +V A+D D GEN + Y + +
Sbjct: 2053 LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAF 2112
Query: 349 --KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSV 390
FSI+ +G L Q D E H M V AK+ PS+
Sbjct: 2113 PVSSYFSINIETGVLYA--QRSFDYEQHKEFAMHVQAKDNGYPSL 2155
Score = 63.7 bits (148), Expect = 4e-08
Identities = 64/206 (31%), Positives = 92/206 (44%), Gaps = 33/206 (16%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-- 1088
V V ++D+ND++PVF + Y+ +V E++ A DAD G N+ Y + +D
Sbjct: 1 VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNYELSANDYF 60
Query: 1089 -TDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+LP I + + L + LDRE + LT++A D G DVND
Sbjct: 61 TLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGG-KPKLSGSTQLIINVEDVND 119
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N P F +SV Y+ +I ENAP GT VAK+FA D D
Sbjct: 120 NPPVFN---------------------QSV-----YQCSITENAPKGTLVAKLFATDMD- 152
Query: 1207 IGNGNGLILYSLPQRKNQQNLGLPSL 1232
+G NG Y + ++ L L SL
Sbjct: 153 VGK-NGETSYEFSKLVPERMLSLFSL 177
Score = 60.9 bits (141), Expect = 3e-07
Identities = 39/155 (25%), Positives = 73/155 (47%), Gaps = 7/155 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I+A D D G A + Y + N + F ++ +G + +++LD ++ ++ + ++
Sbjct: 582 INAYDPDTGDNAKIIYSIAGTNIKSTFDINPTSGKITTKRDLDFES-----VQSYEIAIE 636
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A ++ AQ +V IE++D NDN PE + + I E+ G + + D+D G
Sbjct: 637 A--MDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGR 694
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
NGE Q+ + S + + + LDRE
Sbjct: 695 NGEVDCQILGAAPFQIVSSSSRYYRIITASFLDRE 729
Score = 57.2 bits (132), Expect = 3e-06
Identities = 43/163 (26%), Positives = 71/163 (43%), Gaps = 13/163 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
IHA D D G A + Y + + N FS++ G L+ ++ D + Q F
Sbjct: 1125 IHASDPDAGDNAKIIYSISNINTEDFPVSPYFSINIETGVLYAQRSFDYE-----QHKEF 1179
Query: 273 VLQVQASQLNNPLKTAQARVEI---ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+++ A +P ++ + I E++D NDN PE + + E+ G + +
Sbjct: 1180 QMKISAKDNGSPPLSSNVTLIIHIIEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIE 1239
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
D+D GENGE Q+ P + S + + N LDRE
Sbjct: 1240 VHDQDSGENGEVECQIIGPSPFQLLSSSSRYYKIVNTGSLDRE 1282
Score = 54.0 bits (124), Expect = 3e-05
Identities = 69/308 (22%), Positives = 122/308 (39%), Gaps = 16/308 (5%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAP-IGPSLTI 130
G ++S + + I DVNDN PIF + Y + E G + I P G + I
Sbjct: 536 GSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKI 595
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
++ G I T D+ + V + A++ +
Sbjct: 596 IYSIA-GTNIKSTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKVLIEII 654
Query: 191 DAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDRKLFSL 246
D D ++ I + I ++ + P + A+ DQD G + +++ ++ S
Sbjct: 655 DENDNAPEISIASLSAPIPEDSM-PGTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVSS 713
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
S + LD + + + + + A+ +P ++ ++++L D+NDN P F
Sbjct: 714 SSRYYRIITASFLDRE-----KVPWYNITILATDKGSPELSSTKSIKLDLSDVNDNPPVF 768
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ--LDDPKGAFSIDPRSGWLTVR 364
Y + EN G S+ ++ A D D G N + Y + DP FSI+ +G V
Sbjct: 769 SKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILMSDP-SPFSINQYTGEHKVV 827
Query: 365 NQTVLDRE 372
LDRE
Sbjct: 828 IMKPLDRE 835
Score = 53.2 bits (122), Expect = 5e-05
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ +QA+ +P + +++++ D+NDN P F Y I EN G S+ ++ A+D
Sbjct: 1822 ITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDI 1881
Query: 334 DQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVV 391
D G+N + Y + + FSI +G + +Q LDRE + + A + +P
Sbjct: 1882 DAGDNAKIIYSIYNTEPSPFSISQHTGEIR-SSQKPLDRETQKDHELILTASDGGDPVKT 1940
Query: 392 GT 393
GT
Sbjct: 1941 GT 1942
Score = 52.0 bits (119), Expect = 1e-04
Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 8/179 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQV 276
IHA D D G A + Y + + F LDS G + + + LD E N + +
Sbjct: 1343 IHASDPDYGNNAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYN---ITI 1399
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ +P +++ + +++ D+NDN P F + EN G S+ ++ A+D D G
Sbjct: 1400 VATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTG 1459
Query: 337 ENGEFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+N + Y + F I L + + LDRE + + + A + NP GT
Sbjct: 1460 DNAKVIYSISSMDNEDFPISSYFSKLVL--EKPLDRETQTIHELILTASDGGNPVRSGT 1516
Score = 49.6 bits (113), Expect = 6e-04
Identities = 38/171 (22%), Positives = 75/171 (43%), Gaps = 8/171 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I DQD G + ++I + +L S S + LD + + + +
Sbjct: 1238 IEVHDQDSGENGEVECQIIGPSPFQLLSSSSRYYKIVNTGSLDREL-----VPWYNITIL 1292
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +P + +++++ D+NDN P F + + EN G S+ + A+D D G
Sbjct: 1293 ATDRGSPQLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPENNLPGASIYSIHASDPDYGN 1352
Query: 338 NGEFTYQLDDPKGA--FSIDPRSG-WLTVRNQTVLDREAHSSLRMKVYAKE 385
N + Y + + G F +D +G + + ++ LDRE + + + A +
Sbjct: 1353 NAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYNITIVATD 1403
Score = 47.6 bits (108), Expect = 0.003
Identities = 44/186 (23%), Positives = 79/186 (42%), Gaps = 25/186 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR----KLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D+D G + Y + ++F+++ NG + ++ D + Q N
Sbjct: 1009 VTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKRSFDYEQHKEFQIN--- 1065
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENLP----NGFSVL 326
+ A +P ++ A + I ++D NDN P+ + E +P G +
Sbjct: 1066 --IMAKDNGSPPLSSNATLIIHIIDQNDNAPKILYPSTESGGSPFFEMVPFASVQGSLIT 1123
Query: 327 QVMATDKDQGENGEFTYQL------DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRM 379
++ A+D D G+N + Y + D P FSI+ +G L Q D E H +M
Sbjct: 1124 KIHASDPDAGDNAKIIYSISNINTEDFPVSPYFSINIETGVLYA--QRSFDYEQHKEFQM 1181
Query: 380 KVYAKE 385
K+ AK+
Sbjct: 1182 KISAKD 1187
Score = 38.3 bits (85), Expect = 1.6
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 5/108 (4%)
Query: 8 LNLQPVDREEDAHLFTYRDLNRTHVSVILAQ--SIDSLVDSDSPQNVVKFRLGCDFDEGD 65
+N +D +A + TY +RT V+ + A SI+ + N++ F D++
Sbjct: 2533 VNASDMDEGTNAQI-TY-SFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEISV 2590
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ G G S V + I+D+NDN P F Y V++ E T G
Sbjct: 2591 Q-AKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENTAVG 2637
Score = 37.5 bits (83), Expect = 2.8
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 24/156 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY-- 1285
G P LS + L++ V DV D + PVF Y+ I EN + L T+
Sbjct: 100 GKPKLSGSTQLIINVEDVND-----NPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVG 154
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
+N + Y + F +D G +++ D E +TYEV++ A
Sbjct: 155 KNGETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDA---------- 204
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
E +L G +++V + DVNDN+P+ T
Sbjct: 205 ---LDNGEHLLTG----HCQLLVTVVDVNDNAPEMT 233
>UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-like
cadherin FATJ protein; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "Fat-like cadherin FATJ protein
- Takifugu rubripes
Length = 2263
Score = 136 bits (329), Expect = 4e-30
Identities = 138/490 (28%), Positives = 224/490 (45%), Gaps = 37/490 (7%)
Query: 412 APLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKS 471
A L++ F + T ++ ++ QL S V VT+ D NDN P FV +N + +
Sbjct: 133 AELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRFVSANTVKIT--E 190
Query: 472 NAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILE 529
+A + +VI ++ D D G N +VLY L N T F I+ ++G + + E + L
Sbjct: 191 DAALHSVIMTIRTEDDDDGSNALVLYYL----NTTAEGTFSIDSSSGEIHLMEMLNRELH 246
Query: 530 GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG 589
L V A D+ + SL V+ +V N D P+F Y+ V +V G
Sbjct: 247 DSLILTVTAIDEGSPRMTTSSSLTVLIEDV------NNHD-PEFSTDLYKVAVREDVRGG 299
Query: 590 TSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA 649
TS+ Q+ D ++ ++ + ++ PF+V+ GV+ V++ L R + Y A
Sbjct: 300 TSLLQVSALD--RDIGMNGEVRYMLDKARPFSVDAVRGVVMVMERLDRESDAEYTLTLTA 357
Query: 650 L---QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
+ + + + V N T V+D+ND + + HV EN + + +
Sbjct: 358 VDLGEPPRSTTAVINIT--VMDIND---FVPSFNPELLTLHVMENEEDFSKLTYQVSALD 412
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
+G + F+++ +I +GT LDRE + V+ +T+IA + G
Sbjct: 413 EDFGANSQLQYFILSGN---NGHFSITLNGTFQILHSLDREVQAVHVVTIIA-IDSGSHP 468
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
G + I + D NDN P F Y + E+S GT M + A+D DEG N
Sbjct: 469 LTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAM---VTASDIDEGVNGELS 525
Query: 827 YTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMI 883
Y L G F +DE +G + F D LDRE +Y+L ++ D T LSS + ++I
Sbjct: 526 YRLAGLDMP-FAIDETSGEL-FTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLI 583
Query: 884 GDENDNKPEF 893
GD ND+ P+F
Sbjct: 584 GDVNDHWPQF 593
Score = 122 bits (293), Expect = 1e-25
Identities = 116/461 (25%), Positives = 202/461 (43%), Gaps = 32/461 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + V + N PVF ++ FS+ + VG+ IG++ A D D G NG + Y
Sbjct: 1192 LSSLIEVTFEITGRNQFPPVFREPDV-TFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYG 1250
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ SP + ++G +++ + E + L +EA D ++ V+
Sbjct: 1251 FTHENQ---DSPLSVGEHSGILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIV 1307
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS--YDLLHGY 614
++V + P P F+ + Y V N IGTS+ ++ +DA ++ Y L G
Sbjct: 1308 LDVN-----DNP--PVFLSSSYTISVPENSEIGTSILDVKADDADSSSNAQMLYSLFSGR 1360
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDER 673
+ FA++ SG IT D +++ A+ A+ L V + + DVN+
Sbjct: 1361 MD--KFAIDPGSGTITTSDIFDYEQERVFEVTVRAMNAGAHPLFSVARVVIQITDVNEFT 1418
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + I+F + G +G++ T+ S G V + + Q
Sbjct: 1419 PTFDKNQYHFIVF--RNARIGTRVGRVTATDGDS---GPAGQVFYTMFGQSKTKGFEIDN 1473
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I+T L RE+ D + + N GV++G + + +++I N PVF + Y
Sbjct: 1474 ISGEIYTSGIL-REQADSRILLKVLARNLGVVTGVDVDETSVHISVTEFNAPVFTSSIYS 1532
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I E+S+ G+ ++I D+ ++ + G F VD ++GV+ + L
Sbjct: 1533 ANITEDSRAGS-----SVITVGVLDQDSSRVIFSIENGNTDLAFVVDPSSGVIS-VNSEL 1586
Query: 854 DREKKIMYKLSLVARDTGG-LSSE-AELIIMIGDENDNKPE 892
DRE Y L+L A +G L +E A +I+ + D NDN P+
Sbjct: 1587 DRELLSFYNLTLKAAPSGSPLDAETANVIVTVVDVNDNPPQ 1627
Score = 115 bits (277), Expect = 9e-24
Identities = 123/488 (25%), Positives = 219/488 (44%), Gaps = 36/488 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
++V V + DANDN+P+F S +Y + + ++ A D DLGQN + Y + +
Sbjct: 985 MDVTVVVTDANDNSPLFSHS-VYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVIDPS 1043
Query: 503 SN-LTITSPFKINPNTGTVSVAESPILEGRHALFV-EASDQPANPSERRYSLAVVTIEVT 560
+ + SP + +++ S + +F + D P R + V +E
Sbjct: 1044 NEEFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPL----RSNTTVTVRLEPI 1099
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ + PY VG+ V T++ Q +N++ + + Y L+ G F
Sbjct: 1100 NFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQ-DINNS--SSAIKYILIGGNASSF-F 1155
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKG 679
++E SG + + + + A+ + LS + T + N V +
Sbjct: 1156 WLQEESGKVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQFPPVFRE- 1214
Query: 680 AHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ F V E+ G+ IG+I H NG + F NQ +++ E I
Sbjct: 1215 --PDVTFSVPEDLVVGSPIGRI-HAEDRDYGTNGAISYGFTHENQDS---PLSVGEHSGI 1268
Query: 739 FTQ-KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
T K LD E +Y + + A+ + + VT+ + D NDNPPVF ++Y +
Sbjct: 1269 LTLIKELDFETDRIYHLQMEAKDGAWFTKSSPL-NVTVIVLDVNDNPPVFLSSSYTISVP 1327
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
ENS+IGT I +D +KA DAD +NA +Y+LF + F +D +G + D D E+
Sbjct: 1328 ENSEIGTSI-LD--VKADDADSSSNAQMLYSLFSGRMDKFAIDPGSGTIT-TSDIFDYEQ 1383
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ------IEENSKV--RIHRE 907
+ ++++++ A + G L S A ++I I D N+ P F++ + N+++ R+ R
Sbjct: 1384 ERVFEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRVGRV 1443
Query: 908 TKLNGTAG 915
T +G +G
Sbjct: 1444 TATDGDSG 1451
Score = 105 bits (253), Expect = 7e-21
Identities = 130/460 (28%), Positives = 189/460 (41%), Gaps = 48/460 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+NV V +LD NDN PVF+ S+ Y S+ N+++GT I VKA D D N +LY L
Sbjct: 1301 LNVTVIVLDVNDNPPVFLSSS-YTISVPENSEIGTSILDVKADDADSSSNAQMLYSLFSG 1359
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVT 560
F I+P +GT++ ++ E + V A + A+P +S+A V I++T
Sbjct: 1360 R----MDKFAIDPGSGTITTSDIFDYEQERVFEVTVRAMNAGAHPL---FSVARVVIQIT 1412
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV 618
+ P F Y F V N IGT VG++ D V Y + G +
Sbjct: 1413 DVNEFT----PTFDKNQYHFIVFRNARIGTRVGRVTATDGDSGPAGQVFYTMF-GQSKTK 1467
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-----TVHVVDVNDER 673
F ++ SG I L R D + NL +VT +VH+
Sbjct: 1468 GFEIDNISGEIYTSGIL----REQADSRILLKVLARNLGVVTGVDVDETSVHISVTEFNA 1523
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V +S I +++ AG+++ + + + V F I N +
Sbjct: 1524 PVFTSSIYSANI--TEDSRAGSSVITV------GVLDQDSSRVIFSIENGNTDLAFVVDP 1575
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I LDRE Y +T+ A G A V + + D NDNPP + +
Sbjct: 1576 SSGVISVNSELDRELLSFYNLTLKAA-PSGSPLDAETANVIVTVVDVNDNPPQLLYTEVQ 1634
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEM-FDVDENTGVVKFIGD 851
+ EN GT + + A D D N F Y L + D +
Sbjct: 1635 --VRENQPQGTIVAK---LTALDPDLPPNQGPFAYWLVNPPTDFSLTPDGELSTTR---- 1685
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
+LDRE Y++ +V RD G LSS A L I I DENDN
Sbjct: 1686 ALDREDTSAYQVLVVVRDAGMPQLSSTAMLYIRIVDENDN 1725
Score = 98.3 bits (234), Expect = 1e-18
Identities = 117/471 (24%), Positives = 210/471 (44%), Gaps = 31/471 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ D Q+ S V+V +LD NDN PVF F ++ + +VGT + D D
Sbjct: 44 TVMVQQGDSQVSS-VSVYFNVLDVNDNPPVFSRGTFSAFLLE-DTRVGTCFLSLNVSDKD 101
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSE 547
G NG V + + F INP++ AE ++ + + V ASD+ P+
Sbjct: 102 SGDNGDVKLSVDGEDEDQV---FFINPSSSLCLKAELDREMQNFYNVTVTASDRVQPPAL 158
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDV 606
+ S A + VT G + + P F+ A + + + + + IR D + N +
Sbjct: 159 QLTSTA--RVYVTVGDVND--NAPRFVSA-NTVKITEDAALHSVIMTIRTEDDDDGSNAL 213
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVH 665
L+ EG F+++ SG I +++ L+R A+ E + ++ ++ TV
Sbjct: 214 VLYYLNTTAEGT-FSIDSSSGEIHLMEMLNRELHDSLILTVTAIDEGSPRMTTSSSLTVL 272
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
+ DVN+ + + ++ G ++ Q+ + + G G VR+++ +
Sbjct: 273 IEDVNNHDPEFSTDLYKVAV--REDVRGGTSLLQV--SALDRDIGM-NGEVRYMLDKARP 327
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNP 784
+ D A G + + LDRE Y +T+ A + + S + +T+ D ND
Sbjct: 328 FSVD---AVRGVVMVMERLDRESDAEYTLTLTAVDLGEPPRSTTAVINITVM--DINDFV 382
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P F +MEN + + K+ + A D D G N+ Y + F + N G
Sbjct: 383 PSFNPELLTLHVMENEEDFS--KLTYQVSALDEDFGANSQLQYFILSGNNGHFSITLN-G 439
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ + SLDRE + ++ ++++A D+G L+ L I++GD NDN+P F
Sbjct: 440 TFQIL-HSLDREVQAVHVVTIIAIDSGSHPLTGTQTLQIIVGDINDNRPAF 489
Score = 91.5 bits (217), Expect = 2e-16
Identities = 110/428 (25%), Positives = 185/428 (43%), Gaps = 40/428 (9%)
Query: 920 EVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
E+ +N+F + F +PE++ +G+ I +++A D D G NG I Y F E P
Sbjct: 1201 EITGRNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHENQDSP- 1259
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFV 1035
LS + E G + + + L E++ + L + A DG + ++V V V
Sbjct: 1260 -LS-----------VGEHSGILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIV 1307
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
DVND+ PVF + Y +V E + V A DAD NA + Y + D F I
Sbjct: 1308 LDVNDNPPVFLSSSYTISVPENSEIGTSILDVKADDADSSSNAQMLYSLFSGRMD-KFAI 1366
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
P +G ++ + D E E + +TV A N DVN+ +P FD
Sbjct: 1367 DPGSGTITTSDIFDYEQERVFEVTVRAM-NAGAHPLFSVARVVIQITDVNEFTP---TFD 1422
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGNG 1212
+ + + N + AT ++ P G +F I N +G
Sbjct: 1423 K------NQYHFIVFRNARIGTRVGRVTATDGDSGPAGQVFYTMFGQSKTKGFEIDNISG 1476
Query: 1213 LILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD-EVEMS----DKPVFISRYYELEIE 1267
I S R+ + L + + + +VT DV + V +S + PVF S Y I
Sbjct: 1477 EIYTSGILREQADSRILLKVLARNLGVVTGVDVDETSVHISVTEFNAPVFTSSIYSANIT 1536
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
E+ A ++++ + + ++ ++ + I N N TD+ FV+DP +G + + DRE+
Sbjct: 1537 EDSRAGSSVITVGVLDQ-DSSRVIFSIENGN-TDL--AFVVDPSSGVISVNSELDRELLS 1592
Query: 1328 TYEVIVRA 1335
Y + ++A
Sbjct: 1593 FYNLTLKA 1600
Score = 90.2 bits (214), Expect = 4e-16
Identities = 101/390 (25%), Positives = 178/390 (45%), Gaps = 44/390 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E++ GT++++++ALD D G+NG++RY L+ R F ++ G
Sbjct: 292 VREDVRGGTSLLQVSALDRDIGMNGEVRY----------------MLDKARPFSVDAVRG 335
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV- 1054
V+V L ES E+ L ++A+D G + + + V D+ND P F +V
Sbjct: 336 VVMVMERLDRESDAEYTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVM 395
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + ++ +V A D DFG N+ L YFI S + F I+ L G + LDRE +
Sbjct: 396 ENEEDFSKLTYQVSALDEDFGANSQLQYFIL-SGNNGHFSIT-LNGTFQILHSLDREVQA 453
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPE----ADEL 1168
+++T++A D+G D+NDN P F A++ ++ P A
Sbjct: 454 VHVVTIIAIDSG-SHPLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVT 512
Query: 1169 SNHNFESVMMIPVYK-ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
++ E V Y+ A ++ I T ++F D + + + +Y L + ++L
Sbjct: 513 ASDIDEGVNGELSYRLAGLDMPFAIDETSGELFTTD---LLDRETVAIYRLVVIGSDKHL 569
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
P LSS+ I+ V + DV D P F++ Y + + A + ++ + +
Sbjct: 570 TWP-LSSSVIVTVLIGDVNDH-----WPQFMNGPYVAYVPTGMVAGSVVCAVGAVDEDID 623
Query: 1288 FKMR-YYILNENDTDIRRTFVIDPRNGTLY 1316
+Y L + +D+ F IDPR+G +Y
Sbjct: 624 LNAELHYSLYGHGSDL---FSIDPRSGNVY 650
Score = 88.2 bits (209), Expect = 2e-15
Identities = 114/465 (24%), Positives = 181/465 (38%), Gaps = 59/465 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ + + I+ + D D G N + Y N+ S D+ E H
Sbjct: 188 ITEDAALHSVIMTIRTEDDDDGSNALVLYYLNTTA---EGTFSIDSSS-------GEIHL 237
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++ R L L ++A+D G+ + + S+ V ++DVN+H P F Y V E
Sbjct: 238 MEMLNREL--HDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVRED 295
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
L +V A D D G N + Y + D PF + + GV+ V LDRE++ +Y
Sbjct: 296 VRGGTSLLQVSALDRDIGMNGEVRYML---DKARPFSVDAVRGVVMVMERLDRESDAEYT 352
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV- 1176
LT+ A D G D+ND P F ELL E +E +F +
Sbjct: 353 LTLTAVDLG-EPPRSTTAVINITVMDINDFVPSFN--PELLTLHVMENEE----DFSKLT 405
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL--------G 1228
+ N+ + + NG IL+SL + ++ G
Sbjct: 406 YQVSALDEDFGANSQLQYFILSGNNGHFSITLNGTFQILHSLDREVQAVHVVTIIAIDSG 465
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
L+ T L + V D+ D ++P F Y + E+ A + ++ E
Sbjct: 466 SHPLTGTQTLQIIVGDIND-----NRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGV 520
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
L+ + F ID +G L+ DRE Y ++V + H+
Sbjct: 521 NGE---LSYRLAGLDMPFAIDETSGELFTTDLLDRETVAIYRLVVIGSDK-------HLT 570
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
+P++ V+ V V I DVND+ P+F NG P V +PT
Sbjct: 571 WPLSSSVI---------VTVLIGDVNDHWPQFMNG--PYVAYVPT 604
Score = 87.8 bits (208), Expect = 2e-15
Identities = 58/173 (33%), Positives = 88/173 (50%), Gaps = 10/173 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D + + Y +I GN F LD NG L LD + +TF L ++A+
Sbjct: 819 AVDADFDNMSLVLYNIIDGNVNNYFMLDHENGLLSTTAALDRE-----DISTFNLTIEAA 873
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+LNNP +A V + +LD NDN P F ++I + E+ P G S +Q+ + D D G N
Sbjct: 874 ELNNPSHRDRATVIVSVLDRNDNAPRFS-QIFSIEVPEDSPVGHSAIQISSFDDDLGTNA 932
Query: 340 EFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
Y + D F+I+ +G++TV+ LDRE +KV A ++ SV
Sbjct: 933 VINYFIIDQLSNVPFTINFITGFITVKRP--LDRETRDQYILKVSANDSAWSV 983
Score = 87.4 bits (207), Expect = 3e-15
Identities = 99/361 (27%), Positives = 159/361 (44%), Gaps = 32/361 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + D N+ P F N Y F + NA++GT +G+V A D D G G V Y
Sbjct: 1401 LFSVARVVIQITDVNEFTPTF-DKNQYHFIVFRNARIGTRVGRVTATDGDSGPAGQVFYT 1459
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT-I 557
+ S T F+I+ +G + S IL E +D +L VVT +
Sbjct: 1460 MFGQSK---TKGFEIDNISGEIYT--SGILR-------EQADSRILLKVLARNLGVVTGV 1507
Query: 558 EVTRGT---KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+V + + + P F + Y + + G+SV + V D + + V + + +G
Sbjct: 1508 DVDETSVHISVTEFNAPVFTSSIYSANITEDSRAGSSVITVGVLDQ-DSSRVIFSIENGN 1566
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDER 673
+ + F V+ SGVI+V +L R Y+ A + L T N V VVDVND
Sbjct: 1567 TD-LAFVVDPSSGVISVNSELDRELLSFYNLTLKAAPSGSPLDAETANVIVTVVDVNDNP 1625
Query: 674 GVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
LL ++ + V+EN G + ++ T + G + + N D ++
Sbjct: 1626 PQLL---YTEV--QVRENQPQGTIVAKL--TALDPDLPPNQGPFAYWLVNPPT---DFSL 1675
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
DG + T + LDRE Y++ V+ + G+ + + I I DENDNP + + T
Sbjct: 1676 TPDGELSTTRALDREDTSAYQVLVVVR-DAGMPQLSSTAMLYIRIVDENDNPSLPRNITI 1734
Query: 793 E 793
E
Sbjct: 1735 E 1735
Score = 85.8 bits (203), Expect = 8e-15
Identities = 102/414 (24%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V + D N+++P F ++LY+ +++ + + GT + +V A+D D+G NG V Y L +
Sbjct: 268 SLTVLIEDVNNHDPEF-STDLYKVAVREDVRGGTSLLQVSALDRDIGMNGEVRYMLDKAR 326
Query: 504 NLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTR 561
PF ++ G V V E E + L + A D P R + AV+ I V
Sbjct: 327 ------PFSVDAVRGVVMVMERLDRESDAEYTLTLTAVDLGEPP---RSTTAVINITVM- 376
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNV-GIGTSVGQIRVNDA-FEQND-VSYDLLHGYEEGV 618
+P F V N Q+ D F N + Y +L G
Sbjct: 377 ---DINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFGANSQLQYFILSGNNGHF 433
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLL 677
+ +G ++ L R + ++ +A+ ++ L+ + V D+ND R
Sbjct: 434 SITL---NGTFQILHSLDREVQAVHVVTIIAIDSGSHPLTGTQTLQIIVGDINDNRPAFT 490
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DG 736
A++ I+ +++ AG + S I G + + +A + AI E G
Sbjct: 491 GEAYNTIVS--EDSPAGTVFAMV---TASDIDEGVNGELSYRLAG---LDMPFAIDETSG 542
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+FT LDRE +YR+ VI + VT+ I D ND+ P F + Y ++
Sbjct: 543 ELFTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLIGDVNDHWPQFMNGPYVAYV 602
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
G+ + + A D D NA Y+L+G G ++F +D +G V G
Sbjct: 603 PTGMVAGSVVCA---VGAVDEDIDLNAELHYSLYGHGSDLFSIDPRSGNVYTTG 653
Score = 84.6 bits (200), Expect = 2e-14
Identities = 113/457 (24%), Positives = 190/457 (41%), Gaps = 33/457 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY-DLQRTS 503
V V++LD NDN P F S ++ + ++ VG ++ + D DLG N ++ Y + + S
Sbjct: 886 VIVSVLDRNDNAPRF--SQIFSIEVPEDSPVGHSAIQISSFDDDLGTNAVINYFIIDQLS 943
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
N+ PF IN TG ++V E R ++ S AN S S+ VT+ VT
Sbjct: 944 NV----PFTINFITGFITVKRPLDRETRDQYILKVS---ANDSAWSVSMD-VTVVVTDAN 995
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVPFAV 622
+ P F + Y + V Q+ DA QN + ++ E F V
Sbjct: 996 DNS----PLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVIDPSNE--EFWV 1049
Query: 623 EERSGVITVVDDLSRYNR--PMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKG 679
SG I L+ N +Y F A +A L T TV + +N L
Sbjct: 1050 NSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTTVTVRLEPINFHPPSFL-- 1107
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
H +I + G + + T + N + +++++ + E G +
Sbjct: 1108 PHRRLIPTPYHMAVGTEV--VKFTAIDQDINNSSSAIKYILIGGNASSFFWLQEESGKVI 1165
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
++ ++ + +++ A ++G + + +VT I N PPVF + E+
Sbjct: 1166 LEQSVEGSINSFFTLSLQA-VDQGYPPLSSLIEVTFEITGRNQFPPVFREPDVTFSVPED 1224
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKK 858
+G+ I I A D D GTN Y E ++ V E++G++ I + LD E
Sbjct: 1225 LVVGSPI---GRIHAEDRDYGTNGAISYGFTHENQDSPLSVGEHSGILTLIKE-LDFETD 1280
Query: 859 IMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEF 893
+Y L + A+D SS + +++ D NDN P F
Sbjct: 1281 RIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVF 1317
Score = 79.8 bits (188), Expect = 5e-13
Identities = 56/168 (33%), Positives = 82/168 (48%), Gaps = 9/168 (5%)
Query: 988 VKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLN--DNISVRVFVKDVNDHFP 1043
V YF+++ +G + +L E S F L I A + N + D +V V V D ND+ P
Sbjct: 839 VNNYFMLDHENGLLSTTAALDREDISTFNLTIEAAELNNPSHRDRATVIVSVLDRNDNAP 898
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F + ++ V E ++ + D D G NA + YFI +++PF I+ +TG ++
Sbjct: 899 RFSQI-FSIEVPEDSPVGHSAIQISSFDDDLGTNAVINYFIIDQLSNVPFTINFITGFIT 957
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V LDRET D+YIL V A D+ D NDNSP F
Sbjct: 958 VKRPLDRETRDQYILKVSANDS----AWSVSMDVTVVVTDANDNSPLF 1001
Score = 79.0 bits (186), Expect = 9e-13
Identities = 79/282 (28%), Positives = 125/282 (44%), Gaps = 45/282 (15%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
P ++ +GT ++K A+D D +N NS I + +A +F + E G
Sbjct: 1116 PYHMAVGTEVVKFTAIDQD--IN-------NSSSAIKYILIGGNA---SSFFWLQEESGK 1163
Query: 1001 VIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
VI+ +S+ S F L++ A+D G L+ I V + N PVF++ F+V E
Sbjct: 1164 VILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQFPPVFREPDVTFSVPE 1223
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+G++ A D D+G N ++Y + D P + +G+L++ ELD ET+ Y
Sbjct: 1224 DLVVGSPIGRIHAEDRDYGTNGAISYGFTHENQDSPLSVGEHSGILTLIKELDFETDRIY 1283
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L + A+D G DVNDN P F LS+
Sbjct: 1284 HLQMEAKD-GAWFTKSSPLNVTVIVLDVNDNPPVF----------------LSSS----- 1321
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
Y ++ EN+ IGT++ V A+D D + N +LYSL
Sbjct: 1322 -----YTISVPENSEIGTSILDVKADDAD--SSSNAQMLYSL 1356
Score = 78.6 bits (185), Expect = 1e-12
Identities = 55/168 (32%), Positives = 90/168 (53%), Gaps = 9/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G + L+Y ++SGN+ FS+ ++NG+ + LD + +QA V +
Sbjct: 408 VSALDEDFGANSQLQYFILSGNNGH-FSI-TLNGTFQILHSLDRE----VQAVHVVTIIA 461
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++PL Q ++I + D+NDN P F + YN + E+ P G V A+D D+G
Sbjct: 462 IDSGSHPLTGTQT-LQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGV 520
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NGE +Y+L F+ID SG L + +LDRE + R+ V +
Sbjct: 521 NGELSYRLAGLDMPFAIDETSGELFTTD--LLDRETVAIYRLVVIGSD 566
Score = 78.6 bits (185), Expect = 1e-12
Identities = 64/233 (27%), Positives = 107/233 (45%), Gaps = 13/233 (5%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I++ N+F D+ F++ N IGT + ++ A D DSG GQ+ Y +
Sbjct: 1408 VIQITDVNEFTPTFDKNQYHFIVFRNARIGTRVGRVTATDGDSGPAGQVFYTMFGQSKTK 1467
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKD 1037
++ + E+ ++ E+ I+ + L N+ + G ++ D SV + V +
Sbjct: 1468 GFEIDNISGEIYTSGILREQADSRILLKVLAR------NLGVVTGVDV-DETSVHISVTE 1520
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
N PVF + Y+ N+ E + V D D ++ + + I+ +TDL F + P
Sbjct: 1521 FNA--PVFTSSIYSANITEDSRAGSSVITVGVLDQD---SSRVIFSIENGNTDLAFVVDP 1575
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+GV+SVN ELDRE Y LT+ A +G DVNDN P+
Sbjct: 1576 SSGVISVNSELDRELLSFYNLTLKAAPSG-SPLDAETANVIVTVVDVNDNPPQ 1627
Score = 78.2 bits (184), Expect = 2e-12
Identities = 113/467 (24%), Positives = 191/467 (40%), Gaps = 41/467 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +T++D ND P F P L M++ + +V A+D D G N + Y + +N
Sbjct: 371 INITVMDINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFGANSQLQYFILSGNN 430
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I N GT + S E + H + + A D ++P +L ++ ++
Sbjct: 431 ----GHFSITLN-GTFQILHSLDREVQAVHVVTIIAIDSGSHPLTGTQTLQIIVGDIN-- 483
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
N+P F G Y V + GT + +D E ++SY L G + +PF
Sbjct: 484 --DNRPA---FTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYRLA-GLD--MPF 535
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLK 678
A++E SG + D L R +Y + ++ LS TV + DVND +
Sbjct: 536 AIDETSGELFTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLIGDVNDHWPQFMN 595
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGT 737
G P + +V G G + + ++ + N + +D +I G
Sbjct: 596 G---PYVAYVP---TGMVAGSVVCA-VGAVDEDIDLNAELHYSLYGHGSDLFSIDPRSGN 648
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++T L + V + V + G + ++I ++ + P + G I
Sbjct: 649 VYTTGVLQWAEDLVLNVHVE---DAGETPKSDTSTISIRFQNIAEFPQISVEIL-NGSIP 704
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN +GT + ++ A A + Y G F VD+ +G + + + LD E
Sbjct: 705 ENVPVGTLVA---VVSA--ASTRAEPVSFYLASGNLDNKFHVDQVSGALT-VDNPLDYED 758
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
K + L + ARD+ SS E+ I I D NDN P+F Q E +V
Sbjct: 759 KKGFALLMEARDSASPPFSSFEEIHISISDINDNYPQFTQAEYRCEV 805
Score = 77.8 bits (183), Expect = 2e-12
Identities = 53/166 (31%), Positives = 86/166 (51%), Gaps = 9/166 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I D D G A + Y L + FS+DS +G + L + L+ + +L +L V
Sbjct: 201 IRTEDDDDGSNALVLYYL-NTTAEGTFSIDSSSGEIHLMEMLNRELHDSL-----ILTVT 254
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P T + + + + D+N++ PEF D Y +++ E++ G S+LQV A D+D G
Sbjct: 255 AIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGTSLLQVSALDRDIGM 314
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NGE Y LD + FS+D G + V + LDRE+ + + + A
Sbjct: 315 NGEVRYMLDKAR-PFSVDAVRGVVMVMER--LDRESDAEYTLTLTA 357
Score = 77.0 bits (181), Expect = 4e-12
Identities = 54/167 (32%), Positives = 76/167 (45%), Gaps = 8/167 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
IHA D+D G + Y N S+ +G L L KELD + + + LQ++
Sbjct: 1234 IHAEDRDYGTNGAISYGFTHENQDSPLSVGEHSGILTLIKELDFETDR-----IYHLQME 1288
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A K++ V + +LD+NDN P F Y IS+ EN G S+L V A D D
Sbjct: 1289 AKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSSSYTISVPENSEIGTSILDVKADDADSSS 1348
Query: 338 NGEFTYQLDDPK-GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N + Y L + F+IDP SG T+ + D E + V A
Sbjct: 1349 NAQMLYSLFSGRMDKFAIDPGSG--TITTSDIFDYEQERVFEVTVRA 1393
Score = 75.8 bits (178), Expect = 9e-12
Identities = 47/164 (28%), Positives = 84/164 (51%), Gaps = 14/164 (8%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + LD E + +Y +TV+ + +S +Y + D NDNPPVF T+ F
Sbjct: 25 GEFLLSRSLDFEVQSLYILTVMVQQGDSQVSSVSVY---FNVLDVNDNPPVFSRGTFSAF 81
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLD 854
++E++++GT N+ +D D G N ++ GE + ++F ++ ++ + + LD
Sbjct: 82 LLEDTRVGTCFLSLNV---SDKDSGDNGDVKLSVDGEDEDQVFFINPSSSLC--LKAELD 136
Query: 855 REKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEF 893
RE + Y +++ A D L+S A + + +GD NDN P F
Sbjct: 137 REMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRF 180
Score = 74.9 bits (176), Expect = 2e-11
Identities = 112/463 (24%), Positives = 192/463 (41%), Gaps = 40/463 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V V + D ND+ P F+ + Y + + G+V+ V AVD D+ N + Y
Sbjct: 573 LSSSVIVTVLIGDVNDHWPQFM-NGPYVAYVPTGMVAGSVVCAVGAVDEDIDLNAELHYS 631
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + F I+P +G +V + +L+ L + + A + + + ++I
Sbjct: 632 LYGHG----SDLFSIDPRSG--NVYTTGVLQWAEDLVLNVHVEDAGETPKS-DTSTISIR 684
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
N + P + NV +GT V + VS+ L G +
Sbjct: 685 FQ-----NIAEFPQISVEILNGSIPENVPVGTLVAVVSAAST-RAEPVSFYLASGNLDN- 737
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVL 676
F V++ SG +TV + L ++ + + +++A+ + +H + D+ND
Sbjct: 738 KFHVDQVSGALTVDNPLDYEDKKGFAL-LMEARDSASPPFSSFEEIHISISDINDNYPQF 796
Query: 677 LKGAHSPIIF--HVKENSAGAAIGQIFHTNMSSI-YGNGTGNVRFLIANQQDVTDDIAIA 733
+ + +F H NMS + Y GNV N + D
Sbjct: 797 TQAEYRCEVFENHPPSWICDVLAVDADFDNMSLVLYNIIDGNV-----NNYFMLDH---- 847
Query: 734 EDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E+G + T LDRE + +T+ AE N S V + + D NDN P F +
Sbjct: 848 ENGLLSTTAALDREDISTFNLTIEAAELNNP--SHRDRATVIVSVLDRNDNAPRFSQ-IF 904
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGD 851
+ E+S +G I + D D GTNA+ Y + + + F ++ TG + +
Sbjct: 905 SIEVPEDSPVGHSAIQ---ISSFDDDLGTNAVINYFIIDQLSNVPFTINFITGFIT-VKR 960
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
LDRE + Y L + A D+ S ++ +++ D NDN P F+
Sbjct: 961 PLDRETRDQYILKVSANDS-AWSVSMDVTVVVTDANDNSPLFS 1002
Score = 74.9 bits (176), Expect = 2e-11
Identities = 110/462 (23%), Positives = 185/462 (40%), Gaps = 32/462 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
SF + +++ D NDN P F + Y + N + V AVD D +VLY++
Sbjct: 778 SFEEIHISISDINDNYPQFTQAE-YRCEVFENHPPSWIC-DVLAVDADFDNMSLVLYNI- 834
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + + F ++ G +S + E L +EA++ NPS R + +V++
Sbjct: 835 --IDGNVNNYFMLDHENGLLSTTAALDREDISTFNLTIEAAEL-NNPSHRDRATVIVSV- 890
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI-RVNDAFEQNDVSYDLLHGYEEG 617
N P + V + +G S QI +D N V +
Sbjct: 891 --LDRNDNAPRFSQI----FSIEVPEDSPVGHSAIQISSFDDDLGTNAVINYFIIDQLSN 944
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
VPF + +G ITV L R R Y + A ++ S+ + TV V D ND +
Sbjct: 945 VPFTINFITGFITVKRPLDRETRDQYILKVSA--NDSAWSVSMDVTVVVTDANDNSPLFS 1002
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+S ++ K+ + Q+ T+ G + F + + + + + G
Sbjct: 1003 HSVYSAVLSETKDKD--VFVVQLVATDADL----GQNSQIFYVIDPSN-EEFWVNSPSGE 1055
Query: 738 IFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
IF++KP L ++Y+ TV A F+ G VT+ +E N +PP F
Sbjct: 1056 IFSKKPLTLPNSSFELYQFTVFA-FDCGDAPLRSNTTVTVRLEPINFHPPSFLPHRRLIP 1114
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ +GTE+ I D + ++A+ + G F + E +G V + S++
Sbjct: 1115 TPYHMAVGTEVVKFTAID-QDINNSSSAIKYILIGGNASSFFWLQEESGKV-ILEQSVEG 1172
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ LSL A D G LSS E+ I N P F +
Sbjct: 1173 SINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQFPPVFRE 1214
Score = 72.1 bits (169), Expect = 1e-10
Identities = 106/459 (23%), Positives = 191/459 (41%), Gaps = 37/459 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D NDN P F Y + ++ GTV V A D D G NG + Y R +
Sbjct: 475 LQIIVGDINDNRPAFT-GEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSY---RLAG 530
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
L + PF I+ +G + + E + L V SD+ + + S +VT+ +
Sbjct: 531 LDM--PFAIDETSGELFTTDLLDRETVAIYRLVVIGSDK--HLTWPLSSSVIVTVLI--- 583
Query: 563 TKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQI-RVNDAFEQNDVSYDLLHGYEEGVPF 620
G+ D P FM PY +V + + G+ V + V++ + N + L+G+ + F
Sbjct: 584 --GDVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGAVDEDIDLNAELHYSLYGHGSDL-F 640
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+++ RSG + L + + E S + ++ ++ + + ++
Sbjct: 641 SIDPRSGNVYTTGVLQWAEDLVLNVHVEDAGETPK-SDTSTISIRFQNIAEFPQISVEIL 699
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ I +V + A + + +GN + N+ V D ++ G +
Sbjct: 700 NGSIPENVPVGTLVAVVSAASTRAEPVSFYLASGN----LDNKFHV-DQVS----GALTV 750
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
PLD E + + + + A + + ++ I I D NDN P F A Y + EN
Sbjct: 751 DNPLDYEDKKGFALLMEAR-DSASPPFSSFEEIHISISDINDNYPQFTQAEYRCEVFENH 809
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ A DAD +L +Y + G F +D G++ +LDRE
Sbjct: 810 PPSWICD----VLAVDADFDNMSLVLYNIIDGNVNNYFMLDHENGLLSTTA-ALDREDIS 864
Query: 860 MYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQI 896
+ L++ A + S A +I+ + D NDN P F+QI
Sbjct: 865 TFNLTIEAAELNNPSHRDRATVIVSVLDRNDNAPRFSQI 903
Score = 71.7 bits (168), Expect = 1e-10
Identities = 88/361 (24%), Positives = 158/361 (43%), Gaps = 38/361 (10%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK-T 1048
F+++ G +++RSL E S + L + G + ++SV V DVND+ PVF + T
Sbjct: 18 FLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDSQVSSVSVYFNVLDVNDNPPVFSRGT 77
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+ F +E+ + L ++ +D D G N ++ + D D F I+P + L + EL
Sbjct: 78 FSAFLLEDTRVGTCFL-SLNVSDKDSGDNGDVKLSVDGEDEDQVFFINP-SSSLCLKAEL 135
Query: 1109 DRETEDKYILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
DRE ++ Y +TV A D DVNDN+P+F + + + +
Sbjct: 136 DREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRFVSANTV-----KITE 190
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQ 1225
+ + H+ +M I NA + A T I + +G I L + R+
Sbjct: 191 DAALHSV--IMTIRTEDDDDGSNALV-LYYLNTTAEGTFSIDSSSGEIHLMEMLNRELHD 247
Query: 1226 NL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
+L G P +++++ L V + DV + P F + Y++ + E+V L
Sbjct: 248 SLILTVTAIDEGSPRMTTSSSLTVLIEDVNNH-----DPEFSTDLYKVAVREDVRGGTSL 302
Query: 1277 VSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+ ++ + N ++RY + D R F +D G + ++ DRE Y + +
Sbjct: 303 LQVSALDRDIGMNGEVRYML------DKARPFSVDAVRGVVMVMERLDRESDAEYTLTLT 356
Query: 1335 A 1335
A
Sbjct: 357 A 357
Score = 70.9 bits (166), Expect = 2e-10
Identities = 110/484 (22%), Positives = 190/484 (39%), Gaps = 77/484 (15%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ E+ P GT + A D+D G+NG++ Y + + +P F I+E
Sbjct: 497 IVSEDSPAGTVFAMVTASDIDEGVNGELSYRL-AGLDMP--------------FAIDETS 541
Query: 999 GHVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + L E+ +RL + D L+ ++ V V + DVNDH+P F Y
Sbjct: 542 GELFTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLIGDVNDHWPQFMNGPYVAY 601
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V V+ V A D D NA L Y + +DL F I P +G + G L +
Sbjct: 602 VPTGMVAGSVVCAVGAVDEDIDLNAELHYSLYGHGSDL-FSIDPRSGNVYTTGVL--QWA 658
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+ +L V D G +D S F + E+ + L+
Sbjct: 659 EDLVLNVHVEDAG--------------ETPKSDTSTISIRFQNIAEFPQISVEILNGSIP 704
Query: 1174 ESV---MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGL 1229
E+V ++ V A P+ +A ++ + +G + P ++++ L
Sbjct: 705 ENVPVGTLVAVVSAASTRAEPVSFYLASGNLDNKFHVDQVSGALTVDNPLDYEDKKGFAL 764
Query: 1230 ---------PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
P SS + ++++D+ D + P F Y E+ EN L
Sbjct: 765 LMEARDSASPPFSSFEEIHISISDIND-----NYPQFTQAEYRCEVFENHPPSWICDVLA 819
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ ++N + Y N D ++ F++D NG L + DRE T+ + + A
Sbjct: 820 VDADFDNMSLVLY--NIIDGNVNNYFMLDHENGLLSTTAALDREDISTFNLTIEA----- 872
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQ 1400
EL + P D V+V + D NDN+P+F ++ +P +P G+
Sbjct: 873 -AELNN---PSHRD--------RATVIVSVLDRNDNAPRF---SQIFSIEVPEDSPVGHS 917
Query: 1401 VMQL 1404
+Q+
Sbjct: 918 AIQI 921
Score = 66.5 bits (155), Expect = 5e-09
Identities = 56/206 (27%), Positives = 101/206 (49%), Gaps = 19/206 (9%)
Query: 156 NSDVHYSI---VSGNDDGHFALESSHKPVLLLRKVLDYDAG-DKEFQLVIMASGKRIHKE 211
N ++H S+ V+ D+G + +S +L+ V ++D + V + R
Sbjct: 242 NRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGTS 301
Query: 212 ILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT 271
+L + A+D+D+G+ +RY L + + FS+D+V G + + + LD +++
Sbjct: 302 LL---QVSALDRDIGMNGEVRYML---DKARPFSVDAVRGVVMVMERLDRESDAE----- 350
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL--QVM 329
+ L + A L P ++ A + I ++D+ND +P F + + ++EN FS L QV
Sbjct: 351 YTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVMEN-EEDFSKLTYQVS 409
Query: 330 ATDKDQGENGEFTY-QLDDPKGAFSI 354
A D+D G N + Y L G FSI
Sbjct: 410 ALDEDFGANSQLQYFILSGNNGHFSI 435
Score = 65.7 bits (153), Expect = 9e-09
Identities = 61/212 (28%), Positives = 100/212 (47%), Gaps = 19/212 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I+ V +N A Q+ + +PE+ P+G + I++++ D D G N I Y ++
Sbjct: 887 IVSVLDRNDNAPRFSQIFSIE-VPEDSPVGHSAIQISSFDDDLGTNAVINYFIIDQLSNV 945
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFV 1035
P F IN G + V R L E+ ++ L +SA D + ++ V V V
Sbjct: 946 P-------------FTINFITGFITVKRPLDRETRDQYILKVSANDSA-WSVSMDVTVVV 991
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D ND+ P+F + Y+ + E + + ++ ATDAD GQN+ + Y I PS+ + +
Sbjct: 992 TDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVIDPSNEEF-WVN 1050
Query: 1096 SPLTGVLSVNG-ELDRETEDKYILTVVARDNG 1126
SP + S L + + Y TV A D G
Sbjct: 1051 SPSGEIFSKKPLTLPNSSFELYQFTVFAFDCG 1082
Score = 64.9 bits (151), Expect = 2e-08
Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I + D DLG A + Y +I F+++ + G + +++ LD + + ++L+V
Sbjct: 921 ISSFDDDLGTNAVINYFIIDQLSNVPFTINFITGFITVKRPLDRETR-----DQYILKVS 975
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A N+ + V + + D NDN P F Y+ + E V+Q++ATD D G+
Sbjct: 976 A---NDSAWSVSMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQ 1032
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N + Y +D F ++ SG + + L + + V+A
Sbjct: 1033 NSQIFYVIDPSNEEFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFA 1078
Score = 63.3 bits (147), Expect = 5e-08
Identities = 97/431 (22%), Positives = 172/431 (39%), Gaps = 31/431 (7%)
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
S+ N VGT++ V A L + NL + F ++ +G ++V
Sbjct: 702 SIPENVPVGTLVAVVSAASTRAEPVSFYL----ASGNLD--NKFHVDQVSGALTVDNPLD 755
Query: 528 LEGRH--ALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + AL +EA D + P + + ++ + P F A Y V N
Sbjct: 756 YEDKKGFALLMEARDSASPPFSSFEEIHISISDIN-------DNYPQFTQAEYRCEVFEN 808
Query: 586 VGIGTSVGQIRVNDAFEQND-VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
+ V+ F+ V Y+++ G F ++ +G+++ L R + ++
Sbjct: 809 HPPSWICDVLAVDADFDNMSLVLYNIIDGNVNNY-FMLDHENGLLSTTAALDREDISTFN 867
Query: 645 FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
A + N N S ATV +V V D + + I +++ G + QI ++
Sbjct: 868 LTIEAAELN-NPSHRDRATV-IVSVLDRNDNAPRFSQIFSIEVPEDSPVGHSAIQI--SS 923
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
G F+I +V I G I ++PLDRE RD Y + V A +
Sbjct: 924 FDDDLGTNAVINYFIIDQLSNVPFTINFIT-GFITVKRPLDRETRDQYILKVSANDSAWS 982
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+S VT+ + D NDN P+F H+ Y + E ++ + ++ ATDAD G N+
Sbjct: 983 VS----MDVTVVVTDANDNSPLFSHSVYSAVLSETK--DKDVFVVQLV-ATDADLGQNSQ 1035
Query: 825 FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIM 882
Y + +E + + + +L +Y+ ++ A D G L S + +
Sbjct: 1036 IFYVIDPSNEEFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTTVTVR 1095
Query: 883 IGDENDNKPEF 893
+ N + P F
Sbjct: 1096 LEPINFHPPSF 1106
Score = 63.3 bits (147), Expect = 5e-08
Identities = 77/332 (23%), Positives = 137/332 (41%), Gaps = 24/332 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--- 123
++++ A + S + VTV + D NDN P+F + Y + E T + + L+A
Sbjct: 971 ILKVSANDSAWSVSMDVTVVVTDANDNSPLFSHSVYSAVLSE-TKDKDVFVVQLVATDAD 1029
Query: 124 IGPSLTIPLTVPRGLTIF----KDIRAFDRDKPNTPNS--DVHYSIVSGNDDGHFALESS 177
+G + I + F F + PNS +++ V D G L S+
Sbjct: 1030 LGQNSQIFYVIDPSNEEFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSN 1089
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMAS-GKRIHKEILFPEPIHAIDQDLGVGAT-LRYEL 235
+ L + + + +I + E++ AIDQD+ ++ ++Y L
Sbjct: 1090 TTVTVRLEPINFHPPSFLPHRRLIPTPYHMAVGTEVV---KFTAIDQDINNSSSAIKYIL 1146
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
I GN F L +G + LE+ ++ + F L +QA P ++ V E
Sbjct: 1147 IGGNASSFFWLQEESGKVILEQSVEGSIN-----SFFTLSLQAVDQGYPPLSSLIEVTFE 1201
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFS 353
+ N P F S+ E+L G + ++ A D+D G NG +Y ++ S
Sbjct: 1202 ITGRNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHENQDSPLS 1261
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ SG LT+ + LD E +++ AK+
Sbjct: 1262 VGEHSGILTLIKE--LDFETDRIYHLQMEAKD 1291
Score = 60.9 bits (141), Expect = 3e-07
Identities = 47/169 (27%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ +DQD + + + + +GN F +D +G + + ELD + + + L ++
Sbjct: 1548 VGVLDQD---SSRVIFSIENGNTDLAFVVDPSSGVISVNSELDREL-----LSFYNLTLK 1599
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +PL A V + ++D+NDN P ++ + + + EN P G V ++ A D D
Sbjct: 1600 AAPSGSPLDAETANVIVTVVDVNDNPP--QLLYTEVQVRENQPQGTIVAKLTALDPDLPP 1657
Query: 338 N-GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N G F Y L +P FS+ P T R LDRE S+ ++ V ++
Sbjct: 1658 NQGPFAYWLVNPPTDFSLTPDGELSTTR---ALDREDTSAYQVLVVVRD 1703
Score = 60.5 bits (140), Expect = 3e-07
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+ L SGN F +D V+G+L ++ LD + + F L ++A +P ++ +
Sbjct: 728 FYLASGNLDNKFHVDQVSGALTVDNPLDYEDKKG-----FALLMEARDSASPPFSSFEEI 782
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKG 350
I + D+NDN P+F Y + EN P + + V+A D D Y + D
Sbjct: 783 HISISDINDNYPQFTQAEYRCEVFENHPPSW-ICDVLAVDADFDNMSLVLYNIIDGNVNN 841
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPS 389
F +D +G L+ LDRE S+ + + A E NPS
Sbjct: 842 YFMLDHENGLLS--TTAALDREDISTFNLTIEAAELNNPS 879
Score = 59.7 bits (138), Expect = 6e-07
Identities = 76/315 (24%), Positives = 132/315 (41%), Gaps = 21/315 (6%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S+ L+VTV + DVNDN P+FL + Y ++V E + G + + + A S + +
Sbjct: 1298 SSPLNVTVIVLDVNDNPPVFLSSSYTISVPENSEIGT-SILDVKADDADSSSNAQMLYSL 1356
Query: 138 LTIFKDIRAFDRDKPNTPNSDVH-------YSI-VSGNDDGHFALESSHKPVLLLRKVLD 189
+ D A D SD+ + + V + G L S + V+ + V +
Sbjct: 1357 FSGRMDKFAIDPGSGTITTSDIFDYEQERVFEVTVRAMNAGAHPLFSVARVVIQITDVNE 1416
Query: 190 YDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
+ DK I+ RI + + A D D G + Y + + K F +D+
Sbjct: 1417 FTPTFDKNQYHFIVFRNARIGTRV---GRVTATDGDSGPAGQVFYTMFGQSKTKGFEIDN 1473
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
++G ++ L A+ + +L+V A L + + N P F
Sbjct: 1474 ISGEIYTSGILREQADSRI-----LLKVLARNLGVVTGVDVDETSVHISVTEFNAPVFTS 1528
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
Y+ +I E+ G SV+ V D+D F+ + + AF +DP SG ++V ++
Sbjct: 1529 SIYSANITEDSRAGSSVITVGVLDQD-SSRVIFSIENGNTDLAFVVDPSSGVISVNSE-- 1585
Query: 369 LDREAHSSLRMKVYA 383
LDRE S + + A
Sbjct: 1586 LDRELLSFYNLTLKA 1600
Score = 59.3 bits (137), Expect = 8e-07
Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 10/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D A + Y L SG K F++D +G++ D + E + +
Sbjct: 1339 VKADDADSSSNAQMLYSLFSGRMDK-FAIDPGSGTITTSDIFDYEQERVFEVTVRAMNAG 1397
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +PL + ARV I++ D+N+ P F+ + Y+ + N G V +V ATD D G
Sbjct: 1398 A----HPLFSV-ARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRVGRVTATDGDSGP 1452
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
G+ Y + F ID SG + +L +A S + +KV A+
Sbjct: 1453 AGQVFYTMFGQSKTKGFEIDNISG--EIYTSGILREQADSRILLKVLAR 1499
Score = 58.8 bits (136), Expect = 1e-06
Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 12/157 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y ++ + LF L ++G L + LD + + + ++L V Q ++ + +
Sbjct: 5 ITYSVLEDDGESLFLLSPLSGEFLLSRSLDFEVQ-----SLYILTVMVQQGDSQVSSVS- 58
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DP 348
V +LD+NDN P F ++ ++E+ G L + +DKD G+NG+ +D D
Sbjct: 59 -VYFNVLDVNDNPPVFSRGTFSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVDGEDE 117
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F I+P S L ++ + LDRE + + V A +
Sbjct: 118 DQVFFINPSSS-LCLKAE--LDREMQNFYNVTVTASD 151
Score = 58.4 bits (135), Expect = 1e-06
Identities = 49/170 (28%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++ D+D G ++ + ++ ++F ++ + SL L+ ELD + + N + + V
Sbjct: 95 LNVSDKDSGDNGDVKLSVDGEDEDQVFFINP-SSSLCLKAELDREMQ-----NFYNVTVT 148
Query: 278 ASQLNNPLK---TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
AS P T+ ARV + + D+NDN P F V + I E+ ++ + D D
Sbjct: 149 ASDRVQPPALQLTSTARVYVTVGDVNDNAPRF-VSANTVKITEDAALHSVIMTIRTEDDD 207
Query: 335 QGENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
G N Y L+ +G FSID SG + +L+RE H SL + V A
Sbjct: 208 DGSNALVLYYLNTTAEGTFSIDSSSG--EIHLMEMLNRELHDSLILTVTA 255
Score = 57.2 bits (132), Expect = 3e-06
Identities = 106/457 (23%), Positives = 178/457 (38%), Gaps = 51/457 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN+P+GT + ++A R E S Y+ L F +++ G
Sbjct: 703 IPENVPVGTLVAVVSA--------ASTRAEPVS-FYLASGNLD-------NKFHVDQVSG 746
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V L E + F L + A D + + + + + D+ND++P F + Y V
Sbjct: 747 ALTVDNPLDYEDKKGFALLMEARDSASPPFSSFEEIHISISDINDNYPQFTQAEYRCEVF 806
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + V A DADF + + Y I + + F + G+LS LDRE
Sbjct: 807 E-NHPPSWICDVLAVDADFDNMSLVLYNIIDGNVNNYFMLDHENGLLSTTAALDREDIST 865
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ LT+ A + D NDN+P+ F ++ + PE D H S
Sbjct: 866 FNLTIEAAELN-NPSHRDRATVIVSVLDRNDNAPR---FSQIFSIEVPE-DSPVGH---S 917
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNLGLPSL 1232
+ I + + NA I + +N I G I P + ++Q L + +
Sbjct: 918 AIQISSFDDDLGTNAVINYFIIDQLSNVPFTINFITGFITVKRPLDRETRDQYILKVSAN 977
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY 1292
S + + V V + + P+F Y + E + V +V L T+
Sbjct: 978 DSAWSVSMDVTVVVTDAN-DNSPLFSHSVYSAVLSETKDKDVFVVQLVATD--------- 1027
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
L +N + +VIDP N + V SP E+ + + S EL + A
Sbjct: 1028 ADLGQNS---QIFYVIDPSNEEFW-VNSPSGEIFSKKPLTL----PNSSFEL-YQFTVFA 1078
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVT 1389
D + + + V VR++ +N + P F R + T
Sbjct: 1079 FDCGDAPLRSNTTVTVRLEPINFHPPSFLPHRRLIPT 1115
Score = 50.0 bits (114), Expect = 5e-04
Identities = 46/143 (32%), Positives = 64/143 (44%), Gaps = 7/143 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D GV L Y L +G D F++D +G LF LD + + V+
Sbjct: 511 VTASDIDEGVNGELSYRL-AGLDMP-FAIDETSGELFTTDLLDRET---VAIYRLVVIGS 565
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
L PL ++ V + + D+ND+ P+F Y + + G V V A D+D
Sbjct: 566 DKHLTWPLSSSVI-VTVLIGDVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGAVDEDIDL 624
Query: 338 NGEFTYQL-DDPKGAFSIDPRSG 359
N E Y L FSIDPRSG
Sbjct: 625 NAELHYSLYGHGSDLFSIDPRSG 647
Score = 48.0 bits (109), Expect = 0.002
Identities = 46/140 (32%), Positives = 62/140 (44%), Gaps = 10/140 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFKK 1047
FV++ G + V L E S + L + A G+ D +V V V DVND+ P
Sbjct: 1571 FVVDPSSGVISVNSELDRELLSFYNLTLKAAPSGSPLDAETANVIVTVVDVNDNPPQLLY 1630
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLPFEISPLTGVLSVNG 1106
T V E Q ++ K+ A D D N Y++ TD F ++P G LS
Sbjct: 1631 T--EVQVRENQPQGTIVAKLTALDPDLPPNQGPFAYWLVNPPTD--FSLTP-DGELSTTR 1685
Query: 1107 ELDRETEDKYILTVVARDNG 1126
LDRE Y + VV RD G
Sbjct: 1686 ALDREDTSAYQVLVVVRDAG 1705
Score = 41.5 bits (93), Expect = 0.17
Identities = 66/270 (24%), Positives = 110/270 (40%), Gaps = 33/270 (12%)
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
+TY + D + F +SPL+G ++ LD E + YILTV+ +
Sbjct: 5 ITYSVLEDDGESLFLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQG---DSQVSSVSVYF 61
Query: 1140 XXXDVNDNSPKFY--AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA 1197
DVNDN P F F L E + + + V +N + +V
Sbjct: 62 NVLDVNDNPPVFSRGTFSAFL----LEDTRVGT----CFLSLNVSDKDSGDNGDVKLSVD 113
Query: 1198 KVFANDTDFIGNGNGLILYSLPQRKNQQNLGL----------PSL--SSTAILMVTVADV 1245
+ FI + L L + R+ Q + P+L +STA + VTV DV
Sbjct: 114 GEDEDQVFFINPSSSLCLKAELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDV 173
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRT 1305
D + P F+S ++I E +A + V + + ++ +L +T T
Sbjct: 174 ND-----NAPRFVSA-NTVKITE--DAALHSVIMTIRTEDDDDGSNALVLYYLNTTAEGT 225
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
F ID +G ++L+ +RE+ D+ + V A
Sbjct: 226 FSIDSSSGEIHLMEMLNRELHDSLILTVTA 255
Score = 36.7 bits (81), Expect = 4.9
Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDA 1483
L A D DIG+N ++RY + ++A F++D V G V V+ L R++
Sbjct: 302 LLQVSALDRDIGMNGEVRYML--DKARPFSVDAVRGVVMVMERLDRES 347
>UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1;
n=3; Gallus gallus|Rep: PREDICTED: similar to dachsous 1
- Gallus gallus
Length = 2641
Score = 135 bits (326), Expect = 1e-29
Identities = 127/487 (26%), Positives = 209/487 (42%), Gaps = 31/487 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T+ ++ S V V + D NDN PVF+ S+ + G V V A D D
Sbjct: 1478 TDQARNVSQRRSSAVTARVFVTDVNDNAPVFLSPAAV--SVTEDRPTGFVALHVVAQDND 1535
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPS 546
LG+NG V Y L+ + F +NP+TG +SV + E +H L V A+D
Sbjct: 1536 LGENGRVSYSLRAGNG---DGRFHLNPSTGALSVVRALNREEVVQHNLTVVAADHGFPRR 1592
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV 606
L+++ ++V + P F YE V N+ G+ V Q+ D
Sbjct: 1593 SATQLLSILVLDV-------NDEAPTFEKPEYEAHVMENLPAGSPVLQVLATD--RDLGA 1643
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+ + +G G PF++ ++G+I L R + + A Q+ ++ ATV +
Sbjct: 1644 NGQVTYGGLSGGPFSIHPQTGLIVTTHPLDREEQEQHVLMVYA-QDGGLPPNLSKATVRI 1702
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
V DE + V EN + A+ + T+ G+ G + + +A+
Sbjct: 1703 T-VGDENDHTPQLESESCSVEVPENQSRVALYTLRATDPD---GDENGRLEYRVADGDPE 1758
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
D I G + T + LDRE+ Y +TV+ + + G + V + + D NDN P
Sbjct: 1759 QDFILDPVSGVLSTARALDREQVAFYSLTVVVQ-DHGTPPRSATMTVNVRVLDLNDNAPG 1817
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
F A+Y + E+ +G+ + ++A D DEGTN Y L E MF ++ +G +
Sbjct: 1818 FAQASYVVEVPEDLPVGSLVLQ---LEAEDPDEGTNGQVTYYLGNESLGMFQIEPQSGRI 1874
Query: 847 KFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+ LDRE++ Y A D+ S+ + + + D ND+ P F + V
Sbjct: 1875 R-SAQELDRERQPSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAF--LHSPVTVS 1931
Query: 904 IHRETKL 910
+ R T L
Sbjct: 1932 LSRHTPL 1938
Score = 126 bits (303), Expect = 6e-27
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 37/474 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + ++V++ D NDN P F S Y + N K G+ I +V A D D G NG V+Y++
Sbjct: 213 SQMTLDVSIQDINDNAPAFNQSR-YHTLISENLKPGSSILQVFASDADEGDNGDVIYEIN 271
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIE 558
R + F I+ TG + + + E R H L V+A D+ +P + A VTI
Sbjct: 272 RRQS-DPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDRAVHPE---VTTAFVTIH 327
Query: 559 VTRGTKGNKPDIPD-FMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYE 615
V R N+P + F+ + G V +I V+D E ++V+ L G
Sbjct: 328 V-RDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGEYSNVNVTLEGG-- 384
Query: 616 EGVPFAVEERSGVITV--VDDL-SRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
+G FA+ + +I + VD L R R YD A L + + V+D+ND
Sbjct: 385 DG-KFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAESTFVLQVIDIND 443
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD-I 730
+ + + I V G+ + Q+ + G V++ I + D
Sbjct: 444 NPPLFDQQEYKQSIPEVVY--PGSFVLQVTARDKDQ---GPNGEVQYSIVHSHDTHSSWF 498
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
AI G I T PLD EK ++TV+A ++G + + V + ++D NDN PVF
Sbjct: 499 AIDPATGIITTAAPLDYEKDPQPQLTVLAT-DRGTPALSSSAVVLVALQDVNDNEPVFRS 557
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDENTG 844
Y + EN+ +GT + ATDAD G Y+L G G F +D++TG
Sbjct: 558 NFYNVSLKENTPVGTCFLQ---VTATDADSGLFGSLSYSL-GSGIGSVVPTQFSIDKHTG 613
Query: 845 VVKFIGDSLDR-EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ LDR E Y ++ A D GGL+S + + + D NDN+P F ++
Sbjct: 614 HL-CTTQPLDRDEGTSAYDFTITAVDGGGLNSMVYVKVFLEDINDNRPVFYPLD 666
Score = 115 bits (276), Expect = 1e-23
Identities = 126/471 (26%), Positives = 206/471 (43%), Gaps = 27/471 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V L D NDN PVF SN Y S+K N VGT +V A D D G G + Y
Sbjct: 535 LSSSAVVLVALQDVNDNEPVF-RSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYS 593
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + + F I+ +TG + + P+ A D + ++V ++
Sbjct: 594 LGSGIGSVVPTQFSIDKHTGHLCTTQ-PLDRDEGT---SAYDFTITAVDGGGLNSMVYVK 649
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
V + + P F Y + + GT+V ++ +D E V+Y ++ G
Sbjct: 650 VF--LEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGNSP 707
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
+ F++ + +GVI++ LS + ++ ++ L NA V++ V
Sbjct: 708 PL-FSLNKDTGVISLSWSLSGKANTLVQL-VISAEDGGGLQAQPNARVNISVVEGTVSPP 765
Query: 677 LKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ + F V E+ GA++G + N T ++ + I++ D +I D
Sbjct: 766 VF-EQAQYFFTVPEDMLQGASVGAVRAQNPPG----HTDDIFYSISSG-DPHGYFSIDSD 819
Query: 736 -GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G + T PLD E + V + V A G +V I + D NDN P F +
Sbjct: 820 TGQLHTSLPLDHESQAVLILDVQAR--SGSPPAYSNTRVKISVSDVNDNAPTFPSPSDSI 877
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ E ++ GT + ++A D D G N + L G F V+ ++G V+ +G L
Sbjct: 878 LLPEATEPGTTVYT---LQAEDRDNGANGQVNFELVSGGDGTFSVERSSGAVRLVG-VLQ 933
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
E Y+LS+VARD+G LSS L++ + E+DN P F+ + +VR
Sbjct: 934 YEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIFDTLTYRVEVR 984
Score = 109 bits (262), Expect = 6e-22
Identities = 138/487 (28%), Positives = 207/487 (42%), Gaps = 71/487 (14%)
Query: 939 LIPENIPIGTTIIKLNALDLDS-GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
++PEN G+++ ALD D G N Q+RY + PP F ++ R
Sbjct: 1406 VVPENAQAGSSVFTFQALDGDGVGPNSQVRYALLRQE--PPGAP----------FHLDSR 1453
Query: 998 HGHVIVARSLPPES--EFRLNISALDGG-NLNDN----ISVRVFVKDVNDHFPVFKKTWY 1050
G + + +SL E+ F L + A D N++ ++ RVFV DVND+ PVF
Sbjct: 1454 SGLLSLHQSLDREAVASFLLVVEATDQARNVSQRRSSAVTARVFVTDVNDNAPVFLSP-A 1512
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+V E + T V V A D D G+N ++Y ++ + D F ++P TG LSV L+R
Sbjct: 1513 AVSVTEDRPTGFVALHVVAQDNDLGENGRVSYSLRAGNGDGRFHLNPSTGALSVVRALNR 1572
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E ++ LTVVA D+G DVND +P F + PE +
Sbjct: 1573 EEVVQHNLTVVAADHG-FPRRSATQLLSILVLDVNDEAPTF---------EKPEYEAHVM 1622
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQ----- 1224
N + + AT + G + I GLI+ + P R+ Q
Sbjct: 1623 ENLPAGSPVLQVLATDRDLGANGQVTYGGLSGGPFSIHPQTGLIVTTHPLDREEQEQHVL 1682
Query: 1225 ----QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
Q+ GLP S A + +TV D D P S +E+ EN + V L +L
Sbjct: 1683 MVYAQDGGLPPNLSKATVRITVGDENDHT-----PQLESESCSVEVPEN-QSRVALYTLR 1736
Query: 1281 LT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
T + EN ++ Y + D D + F++DP +G L R+ DRE Y + V
Sbjct: 1737 ATDPDGDENGRLEYRVA---DGDPEQDFILDPVSGVLSTARALDREQVAFYSLTV----- 1788
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
V +D + V VR+ D+NDN+P F + V +P P G
Sbjct: 1789 ------------VVQDHGTPPRSATMTVNVRVLDLNDNAPGFAQAS--YVVEVPEDLPVG 1834
Query: 1399 YQVMQLK 1405
V+QL+
Sbjct: 1835 SLVLQLE 1841
Score = 103 bits (246), Expect = 5e-20
Identities = 172/679 (25%), Positives = 274/679 (40%), Gaps = 104/679 (15%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDDIAIAED-GTIFTQKPLD 745
+E AG IG I S+ GT + I+ Q+ VT D+ I E+ G I T + LD
Sbjct: 30 EEQPAGTIIGDI-----SAGLPPGTSAYMYFISAQEGSGVTTDLWIDENRGIIKTARVLD 84
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF--EHATYEGFIMENSKIG 803
RE RD Y + IA +G+ +V I + D ND+ P F +H+T++ I E++ +G
Sbjct: 85 RETRDHY--SFIAVTPEGIT-----VEVNIQVNDINDHAPAFPKQHSTFQ--IPEHTPVG 135
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTG------VVKFIGDSLDRE 856
+ +D A DAD G Y + G+ + F ++ G + + + LDRE
Sbjct: 136 SRFPLD---PAFDADSGLLNTQGYVIKGDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRE 192
Query: 857 KKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
+ Y L L A D G SS+ L + I D NDN P FNQ R H N
Sbjct: 193 NRSSYSLVLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQ------SRYHTLISENLKP 246
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
G +I++V FA D D+ +N G I ++N D +
Sbjct: 247 GSSILQV-----FASDADE-------GDN---GDVIYEINRRQSDP-----------DQY 280
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF 1034
+ S+ L + + + H V+ AR E + + NDN
Sbjct: 281 FTIDSRTGVIKLNKGLDYEVRKVHELVVQARDRAVHPEVTTAFVTIHVRDYNDNQPTMTI 340
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ D P + + QY R + +D D+G+ +N+ ++ D
Sbjct: 341 IFLSEDGSPQISE-----GAQPGQYVAR----ISVSDPDYGEYSNVNVTLEGGDGKFALT 391
Query: 1095 ISP-LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+ ++ V+ LDRE D Y L V A D+G D+NDN P F
Sbjct: 392 TKDNIIYLICVDQLLDREERDSYDLRVTATDSG-TPPLRAESTFVLQVIDINDNPPLF-- 448
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD----FIGN 1209
+ E+K + + +F V+ + N + ++ V ++DT I
Sbjct: 449 --DQQEYKQSIPEVVYPGSF--VLQVTARDKDQGPNGEVQYSI--VHSHDTHSSWFAIDP 502
Query: 1210 GNGLILYSLP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFIS 1259
G+I + P ++ Q L G P+LSS+A+++V + DV D ++PVF S
Sbjct: 503 ATGIITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVND-----NEPVFRS 557
Query: 1260 RYYELEIEENVNAPVELVSLNLTEHYEN-FKMRYYILNENDTDIRRT-FVIDPRNGTLYL 1317
+Y + ++EN + + T+ F Y L + T F ID G L
Sbjct: 558 NFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGSVVPTQFSIDKHTGHLCT 617
Query: 1318 VRSPDR-EVKDTYEVIVRA 1335
+ DR E Y+ + A
Sbjct: 618 TQPLDRDEGTSAYDFTITA 636
Score = 100 bits (239), Expect = 4e-19
Identities = 133/481 (27%), Positives = 197/481 (40%), Gaps = 52/481 (10%)
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HA 533
G+VIG V PD G + Y + F ++ TG + A E R H
Sbjct: 1310 GSVIGSV--APPDAPARGQLTYTVIGGGG---DGTFVVDSVTGEIYAARELDYEARARHT 1364
Query: 534 LFVEASD-QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
L V A D Q PS R L +V I V + P F P V N G+SV
Sbjct: 1365 LQVSAEDTQHGYPSSR---LVLVQILV----QDCNDQAPTFPEDPITIVVPENAQAGSSV 1417
Query: 593 GQIRVNDAF---EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA 649
+ D + V Y LL G PF ++ RSG++++ L R + A
Sbjct: 1418 FTFQALDGDGVGPNSQVRYALLRQEPPGAPFHLDSRSGLLSLHQSLDREAVASFLLVVEA 1477
Query: 650 LQENANLS----IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNM 705
+ N+S A V V DVND V L SP V E+ +
Sbjct: 1478 TDQARNVSQRRSSAVTARVFVTDVNDNAPVFL----SPAAVSVTEDRPTGFVALHVVAQD 1533
Query: 706 SSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
+ + NG + L A D + G + + L+RE+ + +TV+A + G
Sbjct: 1534 NDLGENGRVSYS-LRAGNGDGRFHLN-PSTGALSVVRALNREEVVQHNLTVVAA-DHGFP 1590
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ ++I + D ND P FE YE +MEN G+ + + ATD D G N
Sbjct: 1591 RRSATQLLSILVLDVNDEAPTFEKPEYEAHVMENLPAGSPVLQ---VLATDRDLGANGQV 1647
Query: 826 MYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLS---SEAELIIM 882
Y G F + TG++ LDRE++ + L + A+D GGL S+A + I
Sbjct: 1648 TYGGLSGGP--FSIHPQTGLI-VTTHPLDREEQEQHVLMVYAQD-GGLPPNLSKATVRIT 1703
Query: 883 IGDENDNKPEFN------QIEEN-SKVRIH--RET----KLNGTAGFTIIEVKPKNKFAL 929
+GDEND+ P+ ++ EN S+V ++ R T NG + + + P+ F L
Sbjct: 1704 VGDENDHTPQLESESCSVEVPENQSRVALYTLRATDPDGDENGRLEYRVADGDPEQDFIL 1763
Query: 930 D 930
D
Sbjct: 1764 D 1764
Score = 97.9 bits (233), Expect = 2e-18
Identities = 89/318 (27%), Positives = 133/318 (41%), Gaps = 18/318 (5%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP---IGPSLTIPLTV 134
S + V + ++D ND P F + P + V E G F F +GP+ + +
Sbjct: 1379 SRLVLVQILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGDGVGPNSQVRYAL 1438
Query: 135 ----PRGLTIFKDIRAFDRDKPNTPNSDVHYS---IVSGNDDGHFALESSHKPVLLLRKV 187
P G D R+ + + + S +V D + V V
Sbjct: 1439 LRQEPPGAPFHLDSRSGLLSLHQSLDREAVASFLLVVEATDQARNVSQRRSSAVTARVFV 1498
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D + F S + A D DLG + Y L +GN F L+
Sbjct: 1499 TDVNDNAPVFLSPAAVSVTEDRPTGFVALHVVAQDNDLGENGRVSYSLRAGNGDGRFHLN 1558
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
G+L + + L+ E +Q N L V A+ P ++A + I +LD+ND P FE
Sbjct: 1559 PSTGALSVVRALN--REEVVQHN---LTVVAADHGFPRRSATQLLSILVLDVNDEAPTFE 1613
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQT 367
Y ++ENLP G VLQV+ATD+D G NG+ TY G FSI P++G + +
Sbjct: 1614 KPEYEAHVMENLPAGSPVLQVLATDRDLGANGQVTYG-GLSGGPFSIHPQTGLIVTTHP- 1671
Query: 368 VLDREAHSSLRMKVYAKE 385
LDRE + VYA++
Sbjct: 1672 -LDREEQEQHVLMVYAQD 1688
Score = 93.1 bits (221), Expect = 5e-17
Identities = 113/456 (24%), Positives = 199/456 (43%), Gaps = 34/456 (7%)
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
++D NDN P+F Y+ S+ G+ + +V A D D G NG V Y + + + T +
Sbjct: 438 VIDINDNPPLFDQQE-YKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHD-THS 495
Query: 509 SPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
S F I+P TG ++ A +P+ + + L V A+D+ P+ S + V + +
Sbjct: 496 SWFAIDPATGIITTA-APLDYEKDPQPQLTVLATDR-GTPA---LSSSAVVLVALQDVND 550
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHGYEEGVP--FA 621
N+P F Y + N +GT Q+ DA +SY L G VP F+
Sbjct: 551 NEPV---FRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGSVVPTQFS 607
Query: 622 VEERSGVITVVDDLSR-YNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+++ +G + L R YDF A+ + L+ + V + D+ND R V
Sbjct: 608 IDKHTGHLCTTQPLDRDEGTSAYDFTITAV-DGGGLNSMVYVKVFLEDINDNRPVFYPLD 666
Query: 681 HSPIIFHVKENSAGAAIGQIF-HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GTI 738
++ I ++ G A+ ++ H ++G T R ++ N + ++ +D G I
Sbjct: 667 YAASIS--TQSMPGTAVLRVTAHDKDEGMHGKVT--YRIVLGNSPPL---FSLNKDTGVI 719
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
L + + ++ + AE G+ + +V I + + +PPVFE A Y + E
Sbjct: 720 SLSWSLSGKANTLVQLVISAEDGGGLQAQPNA-RVNISVVEGTVSPPVFEQAQYFFTVPE 778
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ G + ++A + T+ +F G+ F +D +TG + LD E +
Sbjct: 779 DMLQGASV---GAVRAQNPPGHTDDIFYSISSGDPHGYFSIDSDTGQL-HTSLPLDHESQ 834
Query: 859 IMYKLSLVARD-TGGLSSEAELIIMIGDENDNKPEF 893
+ L + AR + S + I + D NDN P F
Sbjct: 835 AVLILDVQARSGSPPAYSNTRVKISVSDVNDNAPTF 870
Score = 93.1 bits (221), Expect = 5e-17
Identities = 118/462 (25%), Positives = 191/462 (41%), Gaps = 35/462 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +++++ + PVF + Y F++ + G +G V+A +P G + Y + S+
Sbjct: 753 VNISVVEGTVSPPVFEQAQ-YFFTVPEDMLQGASVGAVRAQNPP-GHTDDIFYSI---SS 807
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F I+ +TG + + E + L ++ + +P YS V I V+
Sbjct: 808 GDPHGYFSIDSDTGQLHTSLPLDHESQAVLILDVQARSGSPPA--YSNTRVKISVS-DVN 864
Query: 565 GNKPDIP---DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N P P D + P G+ V T + R N A Q V+++L+ G +G F+
Sbjct: 865 DNAPTFPSPSDSILLPEATEPGTTVY--TLQAEDRDNGANGQ--VNFELVSG-GDGT-FS 918
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGA 680
VE SG + +V L Y VA LS VHV +D +
Sbjct: 919 VERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIF---- 974
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ + V E G + F + + + + D ++E G ++
Sbjct: 975 -DTLTYRV-EVREGVPVSTRFLQVRALARDAEDVTLTYHLRADGDAASFGIMSESGWLYV 1032
Query: 741 QKPLDREKRDVYRMTVIAEF----NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ LDRE RD+Y +TV+A + G G V I I DENDN P Y +
Sbjct: 1033 KSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSPRLSEERYFFTV 1092
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN G+ + + A+D D G N+ Y L + F + TG + SLDRE
Sbjct: 1093 PENQAPGSSV---GRVMASDRDAGQNSRLTYRLL-QHDSNFLIHTQTGELS-TKHSLDRE 1147
Query: 857 KKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQI 896
+ Y+L ++ +D G S+ + + + DENDN P F I
Sbjct: 1148 LQSSYQLLVIVQDGGAPPRSATGTIYVTVLDENDNAPVFLHI 1189
Score = 91.5 bits (217), Expect = 2e-16
Identities = 59/172 (34%), Positives = 85/172 (49%), Gaps = 8/172 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D L Y + G+ + F LD V+G L + LD + Q + L V
Sbjct: 1735 LRATDPDGDENGRLEYRVADGDPEQDFILDPVSGVLSTARALDRE-----QVAFYSLTVV 1789
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
P ++A V + +LDLNDN P F Y + + E+LP G VLQ+ A D D+G
Sbjct: 1790 VQDHGTPPRSATMTVNVRVLDLNDNAPGFAQASYVVEVPEDLPVGSLVLQLEAEDPDEGT 1849
Query: 338 NGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
NG+ TY L ++ G F I+P+SG +R+ LDRE S A ++ P
Sbjct: 1850 NGQVTYYLGNESLGMFQIEPQSG--RIRSAQELDRERQPSYSFLAKAVDSAP 1899
Score = 90.2 bits (214), Expect = 4e-16
Identities = 114/455 (25%), Positives = 184/455 (40%), Gaps = 36/455 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V++++ D NDN P F PS + + GT + ++A D D G NG V ++L
Sbjct: 852 SNTRVKISVSDVNDNAPTF-PSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQVNFELV 910
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAV-VTI 557
+ T F + ++G V + E A L + A D ++L V V
Sbjct: 911 SGGDGT----FSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQA 966
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEE 616
E G P F Y V V + T Q+R A + DV+ L +
Sbjct: 967 EHDNG--------PIFDTLTYRVEVREGVPVSTRFLQVRAL-ARDAEDVTLTYHLRADGD 1017
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL---QENANLSIVTNATVHVVDVNDER 673
F + SG + V L R R +Y +A + + T + + + DE
Sbjct: 1018 AASFGIMSESGWLYVKSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDEN 1077
Query: 674 GVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + F V EN A G+++G++ M+S G N R Q ++ +
Sbjct: 1078 DNSPRLSEERYFFTVPENQAPGSSVGRV----MASDRDAGQ-NSRLTYRLLQHDSNFLIH 1132
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT- 791
+ G + T+ LDRE + Y++ VI + + G + + + + DENDN PVF H T
Sbjct: 1133 TQTGELSTKHSLDRELQSSYQLLVIVQ-DGGAPPRSATGTIYVTVLDENDNAPVFLHITG 1191
Query: 792 ---YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
++E G + ++A D DEG N Y+L G E F + TG ++
Sbjct: 1192 GQELPVQVLEEKPSGLLVAS---LQAKDPDEGENGTITYSLTGAWAERFTLHTATGELR- 1247
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
L R + Y ++ A D G + I+ I
Sbjct: 1248 TATVLRRADRAEYVFTVTASDRGMVPCTTSAIVRI 1282
Score = 88.6 bits (210), Expect = 1e-15
Identities = 117/479 (24%), Positives = 199/479 (41%), Gaps = 39/479 (8%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFS---MKSNAKVGTVIGKVKAVDPDLGQ 491
+ E +FV + V D NDN P L E + A+ G + ++ DPD G+
Sbjct: 316 HPEVTTAFVTIHVR--DYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGE 373
Query: 492 NGMVLYDLQR-TSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSER 548
V L+ +T+ I + V + E R + L V A+D P
Sbjct: 374 YSNVNVTLEGGDGKFALTTKDNI---IYLICVDQLLDREERDSYDLRVTATDSGTPPLRA 430
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
+ + I++ + P P F Y+ + V G+ V Q+ D + +V
Sbjct: 431 ESTFVLQVIDIN-----DNP--PLFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEV 483
Query: 607 SYDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATV 664
Y ++H ++ FA++ +G+IT L P +A LS V
Sbjct: 484 QYSIVHSHDTHSSWFAIDPATGIITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLV 543
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSS-IYGNGTGNVRFLIAN 722
+ DVND V ++ +KEN+ G Q+ T+ S ++G+ + ++ I +
Sbjct: 544 ALQDVNDNEPVFRSNFYN---VSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGS 600
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
I G + T +PLDR++ Y T+ A G+ S + V +++ED N
Sbjct: 601 VVPTQFSID-KHTGHLCTTQPLDRDEGTSAYDFTITAVDGGGLNS---MVYVKVFLEDIN 656
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVD 840
DN PVF Y I S GT + + A D DEG + Y + G +F ++
Sbjct: 657 DNRPVFYPLDYAASISTQSMPGTAVLR---VTAHDKDEGMHGKVTYRIVLGNSPPLFSLN 713
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEFNQIE 897
++TGV+ + SL + + +L + A D GGL ++ A + I + + + P F Q +
Sbjct: 714 KDTGVIS-LSWSLSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVSPPVFEQAQ 771
Score = 88.2 bits (209), Expect = 2e-15
Identities = 56/190 (29%), Positives = 92/190 (48%), Gaps = 13/190 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P+GT +++ A D DSGL G + Y S + V F I++ G
Sbjct: 564 LKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGI----------GSVVPTQFSIDKHTG 613
Query: 1000 HVIVARSLPPE---SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
H+ + L + S + I+A+DGG LN + V+VF++D+ND+ PVF Y ++
Sbjct: 614 HLCTTQPLDRDEGTSAYDFTITAVDGGGLNSMVYVKVFLEDINDNRPVFYPLDYAASIST 673
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ +V A D D G + +TY I ++ F ++ TGV+S++ L +
Sbjct: 674 QSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGNSPPLFSLNKDTGVISLSWSLSGKANTLV 733
Query: 1117 ILTVVARDNG 1126
L + A D G
Sbjct: 734 QLVISAEDGG 743
Score = 86.2 bits (204), Expect = 6e-15
Identities = 109/453 (24%), Positives = 187/453 (41%), Gaps = 42/453 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + +LD ND P F YE + N G+ + +V A D DLG NG V Y
Sbjct: 1598 LSILVLDVNDEAPTFEKPE-YEAHVMENLPAGSPVLQVLATDRDLGANGQVTY-----GG 1651
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
L+ PF I+P TG + V P+ + +H L V A D P +L+ T+ +T
Sbjct: 1652 LS-GGPFSIHPQTGLI-VTTHPLDREEQEQHVLMVYAQDGGLPP-----NLSKATVRITV 1704
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVG-IGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
G + + P V N + + D E + Y + G E F
Sbjct: 1705 GDEND--HTPQLESESCSVEVPENQSRVALYTLRATDPDGDENGRLEYRVADGDPE-QDF 1761
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLK 678
++ SGV++ L R Y V +Q++ S V V+D+ND
Sbjct: 1762 ILDPVSGVLSTARALDREQVAFYSL-TVVVQDHGTPPRSATMTVNVRVLDLNDNAPGF-- 1818
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAIAEDGT 737
A + + V E+ +G + + GT G V + + N+ I + G
Sbjct: 1819 -AQASYVVEVPED---LPVGSLVLQLEAEDPDEGTNGQVTYYLGNESLGMFQIE-PQSGR 1873
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I + + LDRE++ Y A + + +VT+ ++D ND+ P F H+ +
Sbjct: 1874 IRSAQELDRERQPSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFLHSPVTVSLS 1933
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG--DSLDR 855
++ + + ++A D D G NA +Y L F ++ TG ++ + SL +
Sbjct: 1934 RHTPLKQVVA---TMRAEDRDAGANASILYRL-ATPNSAFSINSYTGDIQLLQPLSSLSQ 1989
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
++ ++ ++A D G LSS ++I + +E
Sbjct: 1990 RQRTLF---ILATDLGQPALSSTGVVVIHVQEE 2019
Score = 85.8 bits (203), Expect = 8e-15
Identities = 82/298 (27%), Positives = 141/298 (47%), Gaps = 34/298 (11%)
Query: 111 PTGEKAFIFLI-APIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDD 169
P G A+++ I A G +T L + I K R DR+ + HYS ++ +
Sbjct: 46 PPGTSAYMYFISAQEGSGVTTDLWIDENRGIIKTARVLDRETRD------HYSFIAVTPE 99
Query: 170 GHFALESSHKPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGV 227
G +E + + + + D+ A K+ + + FP +P A D D G+
Sbjct: 100 G-ITVEVN----IQVNDINDHAPAFPKQHSTFQIPEHTPVGSR--FPLDP--AFDADSGL 150
Query: 228 GATLRYELISGNDRKLFSLDS---VNGSLFLEKELD--LDAEHNLQANTFVLQVQASQLN 282
T Y + N + F L++ NG L+L+ + LD E+ +++ L ++A
Sbjct: 151 LNTQGYVIKGDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRENR---SSYSLVLEAYDGG 207
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
P +++Q +++ + D+NDN P F Y+ I ENL G S+LQV A+D D+G+NG+
Sbjct: 208 TPPRSSQMTLDVSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDADEGDNGDVI 267
Query: 343 YQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE--TNPSVVGTF 394
Y+++ DP F+ID R+G ++ LD E + V A++ +P V F
Sbjct: 268 YEINRRQSDPDQYFTIDSRTG--VIKLNKGLDYEVRKVHELVVQARDRAVHPEVTTAF 323
Score = 85.0 bits (201), Expect = 1e-14
Identities = 108/462 (23%), Positives = 183/462 (39%), Gaps = 35/462 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +++ D NDN+P + Y F++ N G+ +G+V A D D GQN + Y L
Sbjct: 1069 VRISITDENDNSPR-LSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRLTYRL----- 1122
Query: 505 LTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
L S F I+ TG +S S L+ + L V D A P ++ V ++
Sbjct: 1123 LQHDSNFLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGGAPPRSATGTIYVTVLD---- 1178
Query: 563 TKGNKPDIPDFMGA---PYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P G P + G+ + Q + D E ++Y L + E
Sbjct: 1179 ENDNAPVFLHITGGQELPVQVLEEKPSGLLVASLQAKDPDEGENGTITYSLTGAWAER-- 1236
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F + +G + L R +R Y F A + + T+A V + + R +
Sbjct: 1237 FTLHTATGELRTATVLRRADRAEYVFTVTA-SDRGMVPCTTSAIVRIQVLPSSRLLPRPD 1295
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
A + ++ G+ IG + + + G + + + + + G I+
Sbjct: 1296 ATVLTLQPLEGVRPGSVIGSVAPPDAPA-----RGQLTYTVIGGGGDGTFVVDSVTGEIY 1350
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+ LD E R + + V AE + + + V I ++D ND P F + EN
Sbjct: 1351 AARELDYEARARHTLQVSAEDTQHGYPSSRLVLVQILVQDCNDQAPTFPEDPITIVVPEN 1410
Query: 800 SKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGK--EMFDVDENTGVVKFIGDSLDRE 856
++ G+ + +A D D G N+ Y L + F +D +G++ + SLDRE
Sbjct: 1411 AQAGSSV---FTFQALDGDGVGPNSQVRYALLRQEPPGAPFHLDSRSGLLS-LHQSLDRE 1466
Query: 857 KKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEF 893
+ L + A D + SS + + D NDN P F
Sbjct: 1467 AVASFLLVVEATDQARNVSQRRSSAVTARVFVTDVNDNAPVF 1508
Score = 82.6 bits (195), Expect = 8e-14
Identities = 53/172 (30%), Positives = 85/172 (49%), Gaps = 12/172 (6%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
G + Y +ISGN++ F + +G++ ++ LD E + + V Q
Sbjct: 2055 GSSGRITYSIISGNEKNAFLIQPSSGAISVQDSSSLDFEASPRLRLVV------QAETTA 2108
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ + L D+NDNLP F++ Y I E+ V+QV+A D DQG NG+ TY +
Sbjct: 2109 SFGFMAINLNLQDVNDNLPRFQLQNYVAFIWESQSYDSPVIQVLADDLDQGMNGQVTYAI 2168
Query: 346 DDP---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
+ G + IDP++G T+ +LDRE S R+ V A + P +VG+
Sbjct: 2169 NQSLPMTGLYHIDPQTG--TITTAAILDREIWSQTRLVVTAMDRGTPPLVGS 2218
Score = 81.0 bits (191), Expect = 2e-13
Identities = 121/480 (25%), Positives = 193/480 (40%), Gaps = 49/480 (10%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I+V N A + F IPE+ P+G+ A D DSGL N++ Y+
Sbjct: 107 IQVNDINDHAPAFPKQHSTFQIPEHTPVGSRFPLDPAFDADSGL-------LNTQGYVIK 159
Query: 979 SKLSADALEVK-RYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
A ++ R + ++V+ L E S + L + A DGG + +++ V
Sbjct: 160 GDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRENRSSYSLVLEAYDGGTPPRSSQMTLDV 219
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDL 1091
++D+ND+ P F ++ Y+ + E + +V A+DAD G N ++ Y I + SD D
Sbjct: 220 SIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDADEGDNGDVIYEINRRQSDPDQ 279
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
F I TGV+ +N LD E + L V ARD D NDN P
Sbjct: 280 YFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDR-AVHPEVTTAFVTIHVRDYNDNQPTM 338
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
L E P+ E + + V I V E + + T+ D F
Sbjct: 339 -TIIFLSEDGSPQISEGAQPG-QYVARISVSDPDYGEYSNVNVTLE---GGDGKFALTTK 393
Query: 1212 GLILY-----SLPQRKNQQNLGL---PSLSSTAILMVTVADVPDEVEMSDK-PVFISRYY 1262
I+Y L R+ + + L + S T L V ++++D P+F + Y
Sbjct: 394 DNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAESTFVLQVIDINDNPPLFDQQEY 453
Query: 1263 ELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRS 1320
+ I E V + V V+ + N +++Y I++ +DT F IDP G
Sbjct: 454 KQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDTH-SSWFAIDPATG------- 505
Query: 1321 PDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+I A Y ++ + +A D V+V ++DVNDN P F
Sbjct: 506 ----------IITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVNDNEPVF 555
Score = 79.4 bits (187), Expect = 7e-13
Identities = 75/282 (26%), Positives = 121/282 (42%), Gaps = 27/282 (9%)
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG-- 679
++E G+I L R R Y F AV + I + V D+ND K
Sbjct: 70 IDENRGIIKTARVLDRETRDHYSFIAVTPE-----GITVEVNIQVNDINDHAPAFPKQHS 124
Query: 680 -----AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
H+P+ + A A + +T I G+ G F + ++ + +
Sbjct: 125 TFQIPEHTPVGSRFPLDPAFDADSGLLNTQGYVIKGDNVGQA-FRLETRRGPNGVLYL-- 181
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+ LDRE R Y + V+ ++ G + + + I+D NDN P F + Y
Sbjct: 182 --DLVVSNVLDRENRSSYSL-VLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHT 238
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTGVVKFIGD 851
I EN K G+ I + A+DADEG N +Y + + + F +D TGV+K +
Sbjct: 239 LISENLKPGSSILQ---VFASDADEGDNGDVIYEINRRQSDPDQYFTIDSRTGVIK-LNK 294
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
LD E + +++L + ARD + A + I + D NDN+P
Sbjct: 295 GLDYEVRKVHELVVQARDRAVHPEVTTAFVTIHVRDYNDNQP 336
Score = 79.4 bits (187), Expect = 7e-13
Identities = 107/466 (22%), Positives = 187/466 (40%), Gaps = 43/466 (9%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+S V +T+ D ND+ P + ++ ++V + ++A DPD +NG + Y
Sbjct: 1695 LSKATVRITVGDENDHTPQLESESCSVEVPENQSRVA--LYTLRATDPDGDENGRLEY-- 1750
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
R ++ F ++P +G +S A + E ++L V D P ++ V +
Sbjct: 1751 -RVADGDPEQDFILDPVSGVLSTARALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVL 1809
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
++ + P F A Y V ++ +G+ V Q+ D E + G E
Sbjct: 1810 DLN-------DNAPGFAQASYVVEVPEDLPVGSLVLQLEAEDPDEGTNGQVTYYLGNESL 1862
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDVNDERGV 675
F +E +SG I +L R +P Y F A A+ S TV V DVND
Sbjct: 1863 GMFQIEPQSGRIRSAQELDRERQPSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPA 1922
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFH-------TNMSSIYGNGTGNVRFLIANQQDVTD 728
L HSP+ + ++ + N S +Y T N F I T
Sbjct: 1923 FL---HSPVTVSLSRHTPLKQVVATMRAEDRDAGANASILYRLATPNSAFSI---NSYTG 1976
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
DI + + + +Q+ +R ++ + + + +S G+ V I++++E F
Sbjct: 1977 DIQLLQPLSSLSQR-----QRTLF--ILATDLGQPALSSTGV--VVIHVQEEPYRGLRFP 2027
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+T E + EN+ GT + I+A + + + G K F + ++G +
Sbjct: 2028 RSTSEVVLPENAAPGTAV---TSIQAVHMGGSSGRITYSIISGNEKNAFLIQPSSGAISV 2084
Query: 849 -IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
SLD E +L + A T A + + + D NDN P F
Sbjct: 2085 QDSSSLDFEASPRLRLVVQAETTASFGFMA-INLNLQDVNDNLPRF 2129
Score = 78.2 bits (184), Expect = 2e-12
Identities = 55/166 (33%), Positives = 80/166 (48%), Gaps = 14/166 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+D G ++Y ++ +D F++D G + LD + + Q L
Sbjct: 470 VTARDKDQGPNGEVQYSIVHSHDTHSSWFAIDPATGIITTAAPLDYEKDPQPQ-----LT 524
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A+ P ++ A V + L D+NDN P F +FYN+S+ EN P G LQV ATD D
Sbjct: 525 VLATDRGTPALSSSAVVLVALQDVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADS 584
Query: 336 GENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSS 376
G G +Y L G+ FSID +G L LDR+ +S
Sbjct: 585 GLFGSLSYSLGSGIGSVVPTQFSIDKHTGHLCTTQP--LDRDEGTS 628
Score = 77.0 bits (181), Expect = 4e-12
Identities = 105/400 (26%), Positives = 168/400 (42%), Gaps = 38/400 (9%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT ++++ A D D G++G++ Y PP F +N+ G + ++ S
Sbjct: 678 GTAVLRVTAHDKDEGMHGKVTYRIVLG-NSPP------------LFSLNKDTGVISLSWS 724
Query: 1007 LPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHF--PVFKKTWYNFNVEEAQYTRR 1062
L ++ +L ISA DGG L + RV + V PVF++ Y F V E
Sbjct: 725 LSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVSPPVFEQAQYFFTVPEDMLQGA 784
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+G V A + G ++ Y I D F I TG L + LD E++ IL V A
Sbjct: 785 SVGAVRAQNPP-GHTDDIFYSISSGDPHGYFSIDSDTGQLHTSLPLDHESQAVLILDVQA 843
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA-FDELLEWKHPEADELSNHNFESVMMIPV 1181
R DVNDN+P F + D +L PEA E +
Sbjct: 844 RSGSPPAYSNTRVKISVS--DVNDNAPTFPSPSDSILL---PEATEPGTTVYTLQAEDRD 898
Query: 1182 YKATIEENAPIGTTVAKVFAND-TDFIGNGNGLILY--SLPQRKN--QQNLGLPSLSSTA 1236
A + N + + F+ + + G++ Y S R + ++ G+P LSST
Sbjct: 899 NGANGQVNFELVSGGDGTFSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTF 958
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN-LTEHYENFKMRYYIL 1295
L+V V + E + P+F + Y +E+ E V + + L E+ + Y++
Sbjct: 959 TLLVHV-----QAEHDNGPIFDTLTYRVEVREGVPVSTRFLQVRALARDAEDVTLTYHLR 1013
Query: 1296 NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ D +F I +G LY+ + DRE +D Y + V A
Sbjct: 1014 ADGDA---ASFGIMSESGWLYVKSALDRETRDLYVLTVLA 1050
Score = 77.0 bits (181), Expect = 4e-12
Identities = 55/164 (33%), Positives = 82/164 (50%), Gaps = 10/164 (6%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y + SG+ FS+DS G L LD H QA +L VQA +P + RV
Sbjct: 803 YSISSGDPHGYFSIDSDTGQLHTSLPLD----HESQA-VLILDVQARS-GSPPAYSNTRV 856
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA 351
+I + D+NDN P F +I + E G +V + A D+D G NG+ ++L G
Sbjct: 857 KISVSDVNDNAPTFPSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQVNFELVSGGDGT 916
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGTF 394
FS++ SG VR VL EA ++ R+ + A+++ P + TF
Sbjct: 917 FSVERSSG--AVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTF 958
Score = 76.6 bits (180), Expect = 5e-12
Identities = 69/224 (30%), Positives = 102/224 (45%), Gaps = 22/224 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE + G+ ++++ A D D G NG+++Y S V+ + S +F I+ G
Sbjct: 457 IPEVVYPGSFVLQVTARDKDQGPNGEVQY---SIVHSHDTHSS--------WFAIDPATG 505
Query: 1000 HVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A L E + + L + A D G L+ + V V ++DVND+ PVF+ +YN +++
Sbjct: 506 IITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVNDNEPVFRSNFYNVSLK 565
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQP---SDTDLPFEISPLTGVLSVNGELDR-E 1111
E +V ATDAD G +L+Y + S F I TG L LDR E
Sbjct: 566 ENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGSVVPTQFSIDKHTGHLCTTQPLDRDE 625
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
Y T+ A D G D+NDN P FY D
Sbjct: 626 GTSAYDFTITAVDGG---GLNSMVYVKVFLEDINDNRPVFYPLD 666
Score = 74.9 bits (176), Expect = 2e-11
Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 4/157 (2%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL-KTA 288
TL Y L + D F + S +G L+++ LD + +L T + S KT
Sbjct: 1007 TLTYHLRADGDAASFGIMSESGWLYVKSALDRETR-DLYVLTVLASAGGSGSGGEARKTG 1065
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
+ V I + D NDN P + Y ++ EN G SV +VMA+D+D G+N TY+L
Sbjct: 1066 TSTVRISITDENDNSPRLSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRLTYRLLQH 1125
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F I ++G L+ ++ LDRE SS ++ V ++
Sbjct: 1126 DSNFLIHTQTGELSTKHS--LDRELQSSYQLLVIVQD 1160
Score = 74.1 bits (174), Expect = 3e-11
Identities = 66/220 (30%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+PE GTT+ L A D D+G NGQ+ +E S D F +
Sbjct: 878 LLPEATEPGTTVYTLQAEDRDNGANGQVNFELVS---------GGDGT-----FSVERSS 923
Query: 999 GHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G V + L E+ +RL+I A D G L+ ++ V V+ +D+ P+F Y V
Sbjct: 924 GAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIFDTLTYRVEV 983
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E +V A D ++ LTY ++ F I +G L V LDRET D
Sbjct: 984 REGVPVSTRFLQVRALARD-AEDVTLTYHLRADGDAASFGIMSESGWLYVKSALDRETRD 1042
Query: 1115 KYILTVVA----RDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y+LTV+A +G D NDNSP+
Sbjct: 1043 LYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSPR 1082
Score = 72.1 bits (169), Expect = 1e-10
Identities = 87/335 (25%), Positives = 144/335 (42%), Gaps = 24/335 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE-LTPTGEKAFIFLI-APIGPSLTIPLTVP 135
S+ +++ V I+D+NDN P F + YH + E L P +F A G + + +
Sbjct: 212 SSQMTLDVSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDADEGDNGDVIYEIN 271
Query: 136 RGLTIFKDIRAFD-RDKPNTPNSDVHYSIVSGNDDGHFALESSHKP----VLLLRKVLDY 190
R + D R N + Y + ++ A + + P + V DY
Sbjct: 272 RRQSDPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDRAVHPEVTTAFVTIHVRDY 331
Query: 191 DAGDKEFQLVIMAS-GKRIHKEILFPEP----IHAIDQDLGVGATLRYELISGNDRKLFS 245
+ ++ ++ G E P I D D G + + L G D K F+
Sbjct: 332 NDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGEYSNVNVTL-EGGDGK-FA 389
Query: 246 LDSVNGSLFLE-KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
L + + ++L + LD E + +++ L+V A+ P A++ ++++D+NDN P
Sbjct: 390 LTTKDNIIYLICVDQLLDRE---ERDSYDLRVTATDSGTPPLRAESTFVLQVIDINDNPP 446
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGW 360
F+ Y SI E + G VLQV A DKDQG NGE Y + D F+IDP +G
Sbjct: 447 LFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDTHSSWFAIDPATGI 506
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
+T LD E ++ V A + + + A
Sbjct: 507 IT--TAAPLDYEKDPQPQLTVLATDRGTPALSSSA 539
Score = 71.7 bits (168), Expect = 1e-10
Identities = 44/122 (36%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+VR+ + D ND+ P + Y F V E Q +G+V A+D D GQN+ LTY + D+
Sbjct: 1068 TVRISITDENDNSPRLSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRLTYRLLQHDS 1127
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ F I TG LS LDRE + Y L V+ +D G D NDN+P
Sbjct: 1128 N--FLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGG-APPRSATGTIYVTVLDENDNAP 1184
Query: 1150 KF 1151
F
Sbjct: 1185 VF 1186
Score = 70.1 bits (164), Expect = 4e-10
Identities = 111/448 (24%), Positives = 172/448 (38%), Gaps = 46/448 (10%)
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR-HAL 534
GT+IG + A P M Q S +T+ I+ N G + A E R H
Sbjct: 35 GTIIGDISAGLPPGTSAYMYFISAQEGSG--VTTDLWIDENRGIIKTARVLDRETRDHYS 92
Query: 535 FVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ 594
F+ + + +T+EV P F F + + +G+
Sbjct: 93 FIAVTPEG------------ITVEVNIQVNDINDHAPAFPKQHSTFQIPEHTPVGSRFPL 140
Query: 595 IRVNDAFEQ--NDVSYDLLHGYEEGVPFAVEERSGV-------ITVVDDLSRYNRPMYDF 645
DA N Y ++ G G F +E R G + V + L R NR Y
Sbjct: 141 DPAFDADSGLLNTQGY-VIKGDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRENRSSYSL 199
Query: 646 EAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHT 703
A S V + D+ND + + +I EN G++I Q+F +
Sbjct: 200 VLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHTLI---SENLKPGSSILQVFAS 256
Query: 704 NMSSIYGNGTGNVRFLIANQQDVTDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFN 761
+ G+V + I +Q D + G I K LD E R V+ + V A +
Sbjct: 257 DADE---GDNGDVIYEINRRQSDPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQAR-D 312
Query: 762 KGVISGAGIYQVTIYIEDENDNPP----VFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
+ V VTI++ D NDN P +F I E ++ G + I +D
Sbjct: 313 RAVHPEVTTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVAR---ISVSDP 369
Query: 818 DEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LS 874
D G + TL G +GK +N + + LDRE++ Y L + A D+G L
Sbjct: 370 DYGEYSNVNVTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLR 429
Query: 875 SEAELIIMIGDENDNKPEFNQIEENSKV 902
+E+ ++ + D NDN P F+Q E +
Sbjct: 430 AESTFVLQVIDINDNPPLFDQQEYKQSI 457
Score = 68.9 bits (161), Expect = 1e-09
Identities = 55/160 (34%), Positives = 76/160 (47%), Gaps = 12/160 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ- 289
L Y +I G F +DSV G ++ +ELD +A LQV A + +++
Sbjct: 1327 LTYTVIGGGGDGTFVVDSVTGEIYAARELDYEARAR-----HTLQVSAEDTQHGYPSSRL 1381
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQL--D 346
V+I + D ND P F D I + EN G SV A D D G N + Y L
Sbjct: 1382 VLVQILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGDGVGPNSQVRYALLRQ 1441
Query: 347 DPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+P GA F +D RSG L++ LDREA +S + V A +
Sbjct: 1442 EPPGAPFHLDSRSGLLSLHQS--LDREAVASFLLVVEATD 1479
Score = 68.9 bits (161), Expect = 1e-09
Identities = 101/415 (24%), Positives = 167/415 (40%), Gaps = 50/415 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN + L A D D NG++ Y AD + ++ F+++ G
Sbjct: 1723 VPEN-QSRVALYTLRATDPDGDENGRLEYRV------------ADG-DPEQDFILDPVSG 1768
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ AR+L E + L + D G + ++V V V D+ND+ P F + Y V
Sbjct: 1769 VLSTARALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVLDLNDNAPGFAQASYVVEVP 1828
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E ++ +++A D D G N +TY++ + F+I P +G + ELDRE +
Sbjct: 1829 EDLPVGSLVLQLEAEDPDEGTNGQVTYYLGNESLGM-FQIEPQSGRIRSAQELDRERQPS 1887
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y A D+ DVND++P F P LS H
Sbjct: 1888 YSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFL--------HSPVTVSLSRHTPLK 1939
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-----LYSLPQRKN-----QQ 1225
++ + + A N I + G I L SL QR+
Sbjct: 1940 QVVATMRAEDRDAGANASILYRLATPNSAFSINSYTGDIQLLQPLSSLSQRQRTLFILAT 1999
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG P+LSST ++++ V + P F E+ + EN AP V+ H
Sbjct: 2000 DLGQPALSSTGVVVIHVQEEPYRGLR-----FPRSTSEVVLPENA-APGTAVTSIQAVHM 2053
Query: 1286 --ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP--DREVKDTYEVIVRAE 1336
+ ++ Y I++ N+ + F+I P +G + + S D E ++V+AE
Sbjct: 2054 GGSSGRITYSIISGNE---KNAFLIQPSSGAISVQDSSSLDFEASPRLRLVVQAE 2105
Score = 68.1 bits (159), Expect = 2e-09
Identities = 55/172 (31%), Positives = 82/172 (47%), Gaps = 13/172 (7%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
F+ + + L D NDN P F N F +S + VI +V A D D G NG V Y + +
Sbjct: 2112 FMAINLNLQDVNDNLPRFQLQNYVAFIWESQSYDSPVI-QVLADDLDQGMNGQVTYAINQ 2170
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ L +T + I+P TGT++ A E + L V A D+ P +L VV +++
Sbjct: 2171 S--LPMTGLYHIDPQTGTITTAAILDREIWSQTRLVVTAMDRGTPPLVGSATLTVVVMDI 2228
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
N P IP P+E V N+ +GT + Q+ ND +SY L+
Sbjct: 2229 N----DNSPTIP----FPWEVRVPENMLLGTQIAQLTGNDVDSGPALSYTLV 2272
Score = 64.9 bits (151), Expect = 2e-08
Identities = 90/368 (24%), Positives = 148/368 (40%), Gaps = 43/368 (11%)
Query: 992 FVINERHGHVIVARSLPPESEFR--LNISALD---GGNLNDNISVRVFVKDVNDHFPVFK 1046
FV++ G + AR L E+ R L +SA D G + + V++ V+D ND P F
Sbjct: 1340 FVVDSVTGEIYAARELDYEARARHTLQVSAEDTQHGYPSSRLVLVQILVQDCNDQAPTFP 1399
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTY-FIQPSDTDLPFEISPLTGVLSV 1104
+ V E + A D D G N+ + Y ++ PF + +G+LS+
Sbjct: 1400 EDPITIVVPENAQAGSSVFTFQALDGDGVGPNSQVRYALLRQEPPGAPFHLDSRSGLLSL 1459
Query: 1105 NGELDRETEDKYILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH 1162
+ LDRE ++L V A D DVNDN+P F +
Sbjct: 1460 HQSLDREAVASFLLVVEATDQARNVSQRRSSAVTARVFVTDVNDNAPVFLS--------- 1510
Query: 1163 PEADELSNHNFESVMMIPVYKA--TIEENAPIGTTVAKVFANDTDFIGNGNGL--ILYSL 1218
P A ++ + + V + EN + ++ + + G ++ +L
Sbjct: 1511 PAAVSVTEDRPTGFVALHVVAQDNDLGENGRVSYSLRAGNGDGRFHLNPSTGALSVVRAL 1570
Query: 1219 PQRK-NQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
+ + Q NL G P S+T +L + V DV DE +KP YE + EN+
Sbjct: 1571 NREEVVQHNLTVVAADHGFPRRSATQLLSILVLDVNDEAPTFEKP-----EYEAHVMENL 1625
Query: 1271 NA--PVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
A PV V + N ++ Y L+ F I P+ G + DRE ++
Sbjct: 1626 PAGSPVLQVLATDRDLGANGQVTYGGLSGG------PFSIHPQTGLIVTTHPLDREEQEQ 1679
Query: 1329 YEVIVRAE 1336
+ ++V A+
Sbjct: 1680 HVLMVYAQ 1687
Score = 64.1 bits (149), Expect = 3e-08
Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 8/168 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSG--LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+PEN+ +GT I +L D+DSG L+ + + ++ + E + F IN
Sbjct: 2243 VPENMLLGTQIAQLTGNDVDSGPALSYTLVLDGDAYAVLEQPAGGPGVAEGRDAFAINSS 2302
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G + + E F+L + A D GN + ++VRV V +++ P+F ++F V
Sbjct: 2303 SGELRSRLTFDYERAKAFQLLVRATDAGNASATVTVRVLVTGEDEYDPIFLSPSFSFEVP 2362
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVL 1102
E + + +G+V ATD D G + + Y + +PS F I+ TG +
Sbjct: 2363 EGAHKGQSIGRVLATDEDEGADGVVLYSLAKPSPY---FAINQTTGTI 2407
Score = 60.9 bits (141), Expect = 3e-07
Identities = 85/331 (25%), Positives = 134/331 (40%), Gaps = 28/331 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE--------LTPTGEKAFIFLIAPI 124
G +S+ V V ++DVNDN P+F Y+V++ E L T A L +
Sbjct: 531 GTPALSSSAVVLVALQDVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSL 590
Query: 125 GPSLT--IPLTVPRGLTIFKDIRAFDRDKP--NTPNSDVHYSIVSGNDDGHFALESSHKP 180
SL I VP +I K +P + + ++ D G L S
Sbjct: 591 SYSLGSGIGSVVPTQFSIDKHTGHLCTTQPLDRDEGTSAYDFTITAVDGG--GLNSMVYV 648
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ L + D S + + + H D+D G+ + Y ++ GN
Sbjct: 649 KVFLEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAH--DKDEGMHGKVTYRIVLGNS 706
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT-AQARVEIELLDL 299
LFSL+ G + L L + +ANT V V +++ L+ ARV I +++
Sbjct: 707 PPLFSLNKDTGVISLSWSL------SGKANTLVQLVISAEDGGGLQAQPNARVNISVVEG 760
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPR 357
+ P FE Y ++ E++ G SV V A G + Y + DP G FSID
Sbjct: 761 TVSPPVFEQAQYFFTVPEDMLQGASVGAVRA-QNPPGHTDDIFYSISSGDPHGYFSIDSD 819
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
+G L LD E+ + L + V A+ +P
Sbjct: 820 TGQL--HTSLPLDHESQAVLILDVQARSGSP 848
Score = 59.3 bits (137), Expect = 8e-07
Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 21/242 (8%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
+ G +I V+ + L + ++PEN GT + + A+ + G +G+I Y
Sbjct: 2008 STGVVVIHVQEEPYRGLRFPRSTSEVVLPENAAPGTAVTSIQAVHM-GGSSGRITY---- 2062
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIV--ARSLPPESEFRLNISALDGGNLNDN-I 1029
S +S + K F+I G + V + SL E+ RL + + +
Sbjct: 2063 ------SIISGNE---KNAFLIQPSSGAISVQDSSSLDFEASPRLRLVVQAETTASFGFM 2113
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-- 1087
++ + ++DVND+ P F+ Y + E+Q + +V A D D G N +TY I S
Sbjct: 2114 AINLNLQDVNDNLPRFQLQNYVAFIWESQSYDSPVIQVLADDLDQGMNGQVTYAINQSLP 2173
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
T L + I P TG ++ LDRE + L V A D G D+NDN
Sbjct: 2174 MTGL-YHIDPQTGTITTAAILDREIWSQTRLVVTAMDRG-TPPLVGSATLTVVVMDINDN 2231
Query: 1148 SP 1149
SP
Sbjct: 2232 SP 2233
Score = 58.4 bits (135), Expect = 1e-06
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 11/168 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + +EL+SG D FS++ +G++ L L +A + +
Sbjct: 892 LQAEDRDNGANGQVNFELVSGGDGT-FSVERSSGAVRLVGVLQYEASAAYRLSIVARDSG 950
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
QL++ T V+ E +DN P F+ Y + + E +P LQV A +D E
Sbjct: 951 VPQLSSTF-TLLVHVQAE----HDNGPIFDTLTYRVEVREGVPVSTRFLQVRALARD-AE 1004
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ TY L D +F I SGWL V+ + LDRE + V A
Sbjct: 1005 DVTLTYHLRADGDAASFGIMSESGWLYVK--SALDRETRDLYVLTVLA 1050
Score = 56.0 bits (129), Expect = 7e-06
Identities = 48/173 (27%), Positives = 75/173 (43%), Gaps = 14/173 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + L Y L+ + F + + G L + LD + + + Q V
Sbjct: 1105 VMASDRDAGQNSRLTYRLLQHDSN--FLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGG 1162
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEF----EVDFYNISIVENLPNGFSVLQVMATDK 333
A P ++A + + +LD NDN P F + ++E P+G V + A D
Sbjct: 1163 A-----PPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEKPSGLLVASLQAKDP 1217
Query: 334 DQGENGEFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+GENG TY L F++ +G L R TVL R + V A +
Sbjct: 1218 DEGENGTITYSLTGAWAERFTLHTATGEL--RTATVLRRADRAEYVFTVTASD 1268
Score = 55.6 bits (128), Expect = 1e-05
Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 7/143 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G + Y L GN+ +F ++ +G + +ELD + + + +F+ +
Sbjct: 1840 LEAEDPDEGTNGQVTYYL--GNESLGMFQIEPQSGRIRSAQELDRERQPSY---SFLAKA 1894
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
S P K+A RV + + D+ND+ P F +S+ + P V + A D+D G
Sbjct: 1895 VDSAPWEP-KSAAVRVTVTVQDVNDHAPAFLHSPVTVSLSRHTPLKQVVATMRAEDRDAG 1953
Query: 337 ENGEFTYQLDDPKGAFSIDPRSG 359
N Y+L P AFSI+ +G
Sbjct: 1954 ANASILYRLATPNSAFSINSYTG 1976
Score = 52.0 bits (119), Expect = 1e-04
Identities = 56/228 (24%), Positives = 98/228 (42%), Gaps = 25/228 (10%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E + GT+ I + +N + + + F +PEN G+++ ++ A D D+G N ++
Sbjct: 1060 EARKTGTSTVRI-SITDENDNSPRLSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRL 1118
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN 1024
Y L+ F+I+ + G + SL E S ++L + DGG
Sbjct: 1119 TYRL---------------LQHDSNFLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGGA 1163
Query: 1025 LNDNISVRVFVK--DVNDHFPVFKKTWYN----FNVEEAQYTRRVLGKVDATDADFGQNA 1078
+ + ++V D ND+ PVF V E + + ++ + A D D G+N
Sbjct: 1164 PPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEKPSGLLVASLQAKDPDEGENG 1223
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+TY + + + F + TG L L R +Y+ TV A D G
Sbjct: 1224 TITYSLTGAWAER-FTLHTATGELRTATVLRRADRAEYVFTVTASDRG 1270
Score = 51.2 bits (117), Expect = 2e-04
Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 7/124 (5%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
R F+++S +G L L D E +A F L V+A+ N T RV + D
Sbjct: 2294 RDAFAINSSSGEL--RSRLTFDYE---RAKAFQLLVRATDAGNASATVTVRVLVTGEDEY 2348
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
D P F ++ + E G S+ +V+ATD+D+G +G Y L P F+I+ +G
Sbjct: 2349 D--PIFLSPSFSFEVPEGAHKGQSIGRVLATDEDEGADGVVLYSLAKPSPYFAINQTTGT 2406
Query: 361 LTVR 364
+ +R
Sbjct: 2407 IYLR 2410
Score = 49.6 bits (113), Expect = 6e-04
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 15/136 (11%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V + ++ +P+F+ S + F + A G IG+V A D D G +G+VLY L +
Sbjct: 2336 VTVRVLVTGEDEYDPIFL-SPSFSFEVPEGAHKGQSIGRVLATDEDEGADGVVLYSLAKP 2394
Query: 503 SNLTITSPFKINPNTGTVSV---AESPILEGR-----HALFVEASDQPANPSERRYSLAV 554
S F IN TGT+ + ++ GR + E + P+ R S A
Sbjct: 2395 SPY-----FAINQTTGTIYLRVDSQPQAGAGRTKREPREMSFEVQARSPLPASRSAS-AQ 2448
Query: 555 VTIEVTRGTKGNKPDI 570
VTI+VT + G PD+
Sbjct: 2449 VTIDVTHTSFGLAPDL 2464
Score = 48.8 bits (111), Expect = 0.001
Identities = 87/409 (21%), Positives = 164/409 (40%), Gaps = 39/409 (9%)
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV 520
P + E + NA GT + ++AV G +G + Y + + + F I P++G +
Sbjct: 2027 PRSTSEVVLPENAAPGTAVTSIQAVHMG-GSSGRITYSIISGNE---KNAFLIQPSSGAI 2082
Query: 521 SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
SV +S L+ EAS + + + + + + + ++P F Y
Sbjct: 2083 SVQDSSSLD------FEASPRLRLVVQAETTASFGFMAINLNLQDVNDNLPRFQLQNYVA 2136
Query: 581 WVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRY 638
++ + + V Q+ +D + V+Y + + ++ ++G IT L R
Sbjct: 2137 FIWESQSYDSPVIQVLADDLDQGMNGQVTYAINQSLPMTGLYHIDPQTGTITTAAILDRE 2196
Query: 639 NRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENSA-GA 695
A+ + +V +AT+ VV D+ND + P V EN G
Sbjct: 2197 IWSQTRLVVTAM-DRGTPPLVGSATLTVVVMDINDNSPTI----PFPWEVRVPENMLLGT 2251
Query: 696 AIGQIFHTNMSS----IYGNGTGNVRFLIANQQ-------DVTDDIAI-AEDGTIFTQKP 743
I Q+ ++ S Y + + Q + D AI + G + ++
Sbjct: 2252 QIAQLTGNDVDSGPALSYTLVLDGDAYAVLEQPAGGPGVAEGRDAFAINSSSGELRSRLT 2311
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
D E+ +++ V A + G S +V + EDE D P+F ++ + E + G
Sbjct: 2312 FDYERAKAFQLLVRAT-DAGNASATVTVRVLVTGEDEYD--PIFLSPSFSFEVPEGAHKG 2368
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I + ATD DEG + + +Y+L + F +++ TG + DS
Sbjct: 2369 QSIGR---VLATDEDEGADGVVLYSL-AKPSPYFAINQTTGTIYLRVDS 2413
Score = 42.7 bits (96), Expect = 0.075
Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 23/155 (14%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G P SS L V++ D+ D ++ SRY+ L I EN+ ++ + ++ E
Sbjct: 207 GTPPRSSQMTLDVSIQDINDNAPAFNQ----SRYHTL-ISENLKPGSSILQVFASDADEG 261
Query: 1288 FKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
Y +N +D + F ID R G + L + D EV+ +E++V+A
Sbjct: 262 DNGDVIYEINRRQSDPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQAR--------DR 313
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
++P E T + V + ++D NDN P T
Sbjct: 314 AVHP------EVTTAF---VTIHVRDYNDNQPTMT 339
Score = 42.7 bits (96), Expect = 0.075
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+I++ A DLD G+NGQ+ Y N +L + + I+ + G + A L
Sbjct: 2148 VIQVLADDLDQGMNGQVTYAIN------------QSLPMTGLYHIDPQTGTITTAAILDR 2195
Query: 1010 E--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E S+ RL ++A+D G L + ++ V V D+ND+ P W V E +
Sbjct: 2196 EIWSQTRLVVTAMDRGTPPLVGSATLTVVVMDINDNSPTIPFPW-EVRVPENMLLGTQIA 2254
Query: 1066 KVDATDADFGQNANLT 1081
++ D D G + T
Sbjct: 2255 QLTGNDVDSGPALSYT 2270
Score = 37.5 bits (83), Expect = 2.8
Identities = 33/141 (23%), Positives = 54/141 (38%), Gaps = 7/141 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D G+ + Y + L+ +D G++ LD + + L V A
Sbjct: 2153 ADDLDQGMNGQVTYAINQSLPMTGLYHIDPQTGTITTAAILDREIWSQTR-----LVVTA 2207
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P A + + ++D+NDN P + + + EN+ G + Q+ D D G
Sbjct: 2208 MDRGTPPLVGSATLTVVVMDINDNSPTIPFP-WEVRVPENMLLGTQIAQLTGNDVDSGPA 2266
Query: 339 GEFTYQLDDPKGAFSIDPRSG 359
+T LD A P G
Sbjct: 2267 LSYTLVLDGDAYAVLEQPAGG 2287
Score = 36.3 bits (80), Expect = 6.5
Identities = 16/34 (47%), Positives = 23/34 (67%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
SA + VTV ++DVND+ P FL +P V++ TP
Sbjct: 1904 SAAVRVTVTVQDVNDHAPAFLHSPVTVSLSRHTP 1937
>UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio
"Cadherin-related neuronal receptor variable 9.; n=1;
Takifugu rubripes|Rep: Homolog of Brachydanio rerio
"Cadherin-related neuronal receptor variable 9. -
Takifugu rubripes
Length = 1254
Score = 134 bits (325), Expect = 1e-29
Identities = 214/931 (22%), Positives = 372/931 (39%), Gaps = 97/931 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ +NV+++ D NDN P F P +L +K N+ VG+ + ++ +D DL +N Y L
Sbjct: 219 TIINVQIS--DVNDNPPRF-PDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLL 275
Query: 501 RTSNLT-ITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTI 557
S + + + IN TG + +S E V+A+D P ++ V +
Sbjct: 276 NNSPKSGVAAMININSETGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFIL 335
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+ + + G+ + + G V +IR DA D Y+ L Y
Sbjct: 336 DENDNSPTILAPYSEH-GSVNSESIPYSAEAGYFVAKIRAVDA----DSGYNALLSYHLS 390
Query: 618 VP-----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
P F + +G I +S + + V + +N + S+ ++ VV V
Sbjct: 391 EPKGNNLFRMGTSTGEIRTKRRMSDNDLKTHPL-VVLVSDNGDPSLSATVSIEVVVVESA 449
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIA 731
+ + H P+ + + I + + G+ +V+ + I+ + + D++
Sbjct: 450 ADIQTQFRHVPMKEESFSDLNLYLLIAIVSVSAIFLLNTGSNSVKAYKISANEHFSVDVS 509
Query: 732 IAEDGT---IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
DGT + +K LDREK+ + ++T+ A + G + +G Q+ + + D NDN PVF
Sbjct: 510 SGADGTSAELVLEKALDREKQALIKLTLTA-VDGGKPARSGTLQILVNVIDVNDNTPVFS 568
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ Y+ + E +GT+I N A D DEG+N Y+L G N KF
Sbjct: 569 QSLYKVRVSEGVPVGTQILKLN---ANDLDEGSNGDLRYSLMKRG--------NVNSEKF 617
Query: 849 IGDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
S+D E +I+ K SL ++G EL + D+ + P SKV
Sbjct: 618 ---SVDPESGEIVVKASLDYEESGAY----ELRVQATDQGAS-PRSGY----SKV----- 660
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
++EV N A ++ + I E+ +GT + ++ D D G NG +
Sbjct: 661 ----------LVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDGGQNGHLS 710
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN- 1024
+ P L ++ K Y+ + +V L E S++ + I A D G
Sbjct: 711 CKIRDS---SPFALKSN---YKSYYSL-------VVDGLLDRETISQYDVTIVATDEGTP 757
Query: 1025 -LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
L+ + V + DVND+ P F N ++E ++ + A DAD NA LTY
Sbjct: 758 PLSSTAVISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADVNDNAKLTYS 817
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGEL------DRETEDKYILTVVARDNGXXXXXXXXXXX 1137
+ S IS + + S G++ + E + V A D+G
Sbjct: 818 LLDSH-QKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQATDSG-VPPLSSNVTV 875
Query: 1138 XXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA 1197
D NDNSP A + E+ S V I A NA + ++
Sbjct: 876 NVFILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS 935
Query: 1198 KVFANDTDFIGNGNGLILYSLPQRKNQ----------QNLGLPSLSSTAILMVTVADVPD 1247
+ N+ +G G I N + G PSLS+T + V V +
Sbjct: 936 EPKGNNLFRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAA 995
Query: 1248 EVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV 1307
+++ + V + ++ + + L + +L E +N K++Y + ++D F
Sbjct: 996 DIQTQFRHVPMKEESFSDLNLYLLIAIVLNATDLDEG-QNGKIKYSFIKRGNSDPSNIFD 1054
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
++ G + + D E YEV V+A Q
Sbjct: 1055 LNSDTGEIKVKGELDYEETPAYEVRVQANDQ 1085
Score = 100 bits (240), Expect = 3e-19
Identities = 119/492 (24%), Positives = 202/492 (41%), Gaps = 41/492 (8%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V V +LD NDN+P + P ++ S+ +A+ G + K++AVD D G N
Sbjct: 324 LSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNA 383
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYS 551
++ Y L + F++ +TG + S H L V SD S
Sbjct: 384 LLSYHLSEPKGNNL---FRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVS 440
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL- 610
+ VV +E + F P + S++ + + + V+ F N S +
Sbjct: 441 IEVVVVESAADIQ------TQFRHVPMKEESFSDLNLYLLIAIVSVSAIFLLNTGSNSVK 494
Query: 611 LHGYEEGVPFAVEERSGV------ITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NAT 663
+ F+V+ SG + + L R + + A+ T
Sbjct: 495 AYKISANEHFSVDVSSGADGTSAELVLEKALDREKQALIKLTLTAVDGGKPARSGTLQIL 554
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIAN 722
V+V+DVND V S ++ V+ S G +G QI N + + G++R+ +
Sbjct: 555 VNVIDVNDNTPVF-----SQSLYKVRV-SEGVPVGTQILKLNANDLDEGSNGDLRYSLMK 608
Query: 723 QQDVTDD--IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ +V + E G I + LD E+ Y + V A ++G +G +V + + D
Sbjct: 609 RGNVNSEKFSVDPESGEIVVKASLDYEESGAYELRVQAT-DQGASPRSGYSKVLVEVLDV 667
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P + I E++ +GT + + + TD D G N + +
Sbjct: 668 NDNAPEISVTSLMSPIKESAGLGTVVAL---VSVTDKDGGQNGHLSCKIRDSSPFALKSN 724
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEE 898
+ + LDRE Y +++VA D G LSS A + + I D NDN P F ++E
Sbjct: 725 YKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAVISVQISDVNDNAPRF--MDE 782
Query: 899 NSKVRIHRETKL 910
N + I +++
Sbjct: 783 NLNIYIKENSRV 794
Score = 99.5 bits (237), Expect = 6e-19
Identities = 120/473 (25%), Positives = 206/473 (43%), Gaps = 38/473 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + + ++D NDN P+F S LY+ + NA VG I + A D D G NG ++Y
Sbjct: 6 LQIRINVIDVNDNYPLFSKS-LYKVQVVENANVGATILTLSATDLDDGVNGELVYSFAER 64
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVT 560
F +N + G +++ + E A + V+A D+ A P + V I+V
Sbjct: 65 GRFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEVIDV- 123
Query: 561 RGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGV 618
N P+I + +P V + G+GT+V + +ND +N ++ + G V
Sbjct: 124 ---NDNAPEISVSSLMSP----VKEDAGLGTAVAMVTINDRDGGKNGLTNCRITG---SV 173
Query: 619 PFAVEE--RSGVITVVD-DLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERG 674
PF ++ ++ VVD L R Y+ A E +L+ T V + DVND
Sbjct: 174 PFMLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVNDNPP 233
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIA 731
+ S + ++KENS G+ + ++ T + S L+ N + V I
Sbjct: 234 ---RFPDSLLNVYLKENSPVGSTVHRL--TTLDSDLNENAKATYHLLNNSPKSGVAAMIN 288
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I +E G I + + + E+ ++ V A + GV + V ++I DENDN P
Sbjct: 289 INSETGDIISLQSFNYEELKTFQFKVQAT-DSGVPPLSSNVTVNVFILDENDNSPTILAP 347
Query: 791 TYEGFIMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVV 846
E + + I + I+A DAD G NAL Y L +G +F + +TG +
Sbjct: 348 YSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTSTGEI 407
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAEL---IIMIGDENDNKPEFNQI 896
+ D + K + L ++ D G S A + ++++ D + +F +
Sbjct: 408 RTKRRMSDNDLK-THPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHV 459
Score = 93.5 bits (222), Expect = 4e-17
Identities = 106/472 (22%), Positives = 198/472 (41%), Gaps = 36/472 (7%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ V V +LD NDN P ++L +K +A +GTV+ V D D GQNG + ++
Sbjct: 657 YSKVLVEVLDVNDNAPEISVTSLMS-PIKESAGLGTVVALVSVTDKDGGQNGHLSCKIRD 715
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+S + S +K + + + + ++ + + A+D+ P S AV++++++
Sbjct: 716 SSPFALKSNYKSYYSLVVDGLLDRETI-SQYDVTIVATDEGTPPLS---STAVISVQIS- 770
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND---VSYDLLHGYEEGV 618
+ P FM ++ N +G + + DA + ND ++Y LL +++ V
Sbjct: 771 ---DVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDA-DVNDNAKLTYSLLDSHQKDV 826
Query: 619 PFA----VEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
+ + +G I + + + F+ A LS V ++D ND
Sbjct: 827 LISTVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNS 886
Query: 674 GVLLKGAHSPIIFHVKENSAG---AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+L +P H NS +A F + ++ + N + +++
Sbjct: 887 PTIL----APYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNL 942
Query: 731 --AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G I T++ + + + V+ N A + + +E D F
Sbjct: 943 FRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFR 1002
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTG 844
H + S + + + ++ ATD DEG N Y+ G +FD++ +TG
Sbjct: 1003 HVPMKE--ESFSDLNLYLLIAIVLNATDLDEGQNGKIKYSFIKRGNSDPSNIFDLNSDTG 1060
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEFN 894
+K G+ LD E+ Y++ + A D G S+ A+L+I I DENDN PE +
Sbjct: 1061 EIKVKGE-LDYEETPAYEVRVQANDQGTTPRSAHAKLLIEIIDENDNAPEIS 1111
Score = 92.7 bits (220), Expect = 7e-17
Identities = 121/474 (25%), Positives = 194/474 (40%), Gaps = 74/474 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P+G+T+ +L LD D N + Y + P S ++A IN G
Sbjct: 244 LKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNS--PKSGVAA-------MININSETG 294
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWY---NF 1052
+I +S E F+ + A D G L+ N++V VF+ D ND+ P + +
Sbjct: 295 DIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSV 354
Query: 1053 NVEEAQYTRRV---LGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGEL 1108
N E Y+ + K+ A DAD G NA L+Y + +P +L F + TG + +
Sbjct: 355 NSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNL-FRMGTSTGEIRTKRRM 413
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH-PEADE 1167
+ L V+ DNG D +F +H P +E
Sbjct: 414 SDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQF---------RHVPMKEE 464
Query: 1168 -LSNHNFESVMMIPVYKATIEENAPIGTTVA-KVFAND---TDFIGNGNG----LILYSL 1218
S+ N ++ I A N + A K+ AN+ D +G L+L
Sbjct: 465 SFSDLNLYLLIAIVSVSAIFLLNTGSNSVKAYKISANEHFSVDVSSGADGTSAELVLEKA 524
Query: 1219 PQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
R+ Q + G P+ S T ++V V DV D + PVF Y++ + E
Sbjct: 525 LDREKQALIKLTLTAVDGGKPARSGTLQILVNVIDVND-----NTPVFSQSLYKVRVSEG 579
Query: 1270 VNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
V +++ LN + E N +RY ++ + + + F +DP +G + + S D E
Sbjct: 580 VPVGTQILKLNANDLDEGSNGDLRYSLMKRGNVNSEK-FSVDPESGEIVVKASLDYEESG 638
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
YE+ V+A Q S P Y KV+V + DVNDN+P+ +
Sbjct: 639 AYELRVQATDQGAS---PRSGYS--------------KVLVEVLDVNDNAPEIS 675
Score = 89.4 bits (212), Expect = 7e-16
Identities = 119/501 (23%), Positives = 201/501 (40%), Gaps = 33/501 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + V + D NDN P F+ NL +K N++VG +I + A D D+ N + Y
Sbjct: 759 LSSTAVISVQISDVNDNAPRFMDENL-NIYIKENSRVGDIITRASAQDADVNDNAKLTYS 817
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
L ++ I++ IN TG + +S E V+A+D P ++ V
Sbjct: 818 LLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNV 877
Query: 555 VTIEVTRGTKGNKPDI--P-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
++ N P I P G+ + + G V +IR DA D Y+ L
Sbjct: 878 FILD----ENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDA----DSGYNAL 929
Query: 612 HGYEEGVP-----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y P F + +G I +S + + V + +N + S+ ++ V
Sbjct: 930 LSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKTHPL-VVLVSDNGDPSLSATVSIEV 988
Query: 667 VDVNDERGVLLKGAHSPIIFH-VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V V + + H P+ + + I + + NG F+ D
Sbjct: 989 VVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLNATDLDEGQNGKIKYSFIKRGNSD 1048
Query: 726 VTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
++ + D G I + LD E+ Y + V A ++G + ++ I I DENDN
Sbjct: 1049 PSNIFDLNSDTGEIKVKGELDYEETPAYEVRVQAN-DQGTTPRSAHAKLLIEIIDENDNA 1107
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P + + E++++GT + +I D D G N + + + G +
Sbjct: 1108 PEISVTSLMTPLKEDAELGTIVA---LITVNDKDGGKNGVAVCKVVGSVPFKLKSNYKNE 1164
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ +LDRE +Y +++ A D G LS+ + + I D NDN P F N +
Sbjct: 1165 YSLVVDGALDRENTSVYNVTVQATDEGDPPLSTIKVITVHISDVNDNAPVFMVPVINVYL 1224
Query: 903 RIHRETKLNGTAGFTIIEVKP 923
R + +T G+ TI V P
Sbjct: 1225 RENSQT---GSVIDTISAVDP 1242
Score = 79.0 bits (186), Expect = 9e-13
Identities = 98/407 (24%), Positives = 168/407 (41%), Gaps = 37/407 (9%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V V +LD NDN+P + P ++ S+ +A+ G + K++AVD D G N
Sbjct: 869 LSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNA 928
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYS 551
++ Y L + F++ +TG + S H L V SD S
Sbjct: 929 LLSYHLSEPKGNNL---FRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVS 985
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
+ VV +E + +P + + + + I + + D + + Y +
Sbjct: 986 IEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLNATDL---DEGQNGKIKYSFI 1042
Query: 612 H--GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVD 668
+ F + +G I V +L P Y+ A + S + ++D
Sbjct: 1043 KRGNSDPSNIFDLNSDTGEIKVKGELDYEETPAYEVRVQANDQGTTPRSAHAKLLIEIID 1102
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT------GNVRFLIAN 722
ND + + + ++ +KE++ I + N NG G+V F +
Sbjct: 1103 ENDNAPEI---SVTSLMTPLKEDAELGTIVALITVNDKDGGKNGVAVCKVVGSVPFKL-- 1157
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ + ++ ++ DG LDRE VY +TV A ++G + I +T++I D ND
Sbjct: 1158 KSNYKNEYSLVVDGA------LDRENTSVYNVTVQAT-DEGDPPLSTIKVITVHISDVND 1210
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
N PVF ++ ENS+ G+ I + I A D D NA +YTL
Sbjct: 1211 NAPVFMVPVINVYLRENSQTGSVI---DTISAVDPDLDHNAKVIYTL 1254
Score = 78.6 bits (185), Expect = 1e-12
Identities = 85/341 (24%), Positives = 151/341 (44%), Gaps = 30/341 (8%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPY--HVTVD-ELTPTGEKA--FIFLIAPIGP 126
+G+ +S+ ++V V+I D NDN P L PY H +V+ E P +A F+ I +
Sbjct: 319 SGVPPLSSNVTVNVFILDENDNSPTIL-APYSEHGSVNSESIPYSAEAGYFVAKIRAVDA 377
Query: 127 S------LTIPLTVPRGLTIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
L+ L+ P+G +F+ +IR R N + +VS N D +
Sbjct: 378 DSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSA 437
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMA-SGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
S + V+++ D + + + S ++ I + G + Y
Sbjct: 438 TVSIE-VVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVSVSAIFLLNTGSNSVKAY 496
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQARV 292
+ IS N+ FS+D +G+ EL L+ + + + L + A P ++ ++
Sbjct: 497 K-ISANEH--FSVDVSSGADGTSAELVLEKALDREKQALIKLTLTAVDGGKPARSGTLQI 553
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDP 348
+ ++D+NDN P F Y + + E +P G +L++ A D D+G NG+ Y L +
Sbjct: 554 LVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNANDLDEGSNGDLRYSLMKRGNVN 613
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
FS+DP SG + V+ LD E + ++V A + S
Sbjct: 614 SEKFSVDPESGEIVVK--ASLDYEESGAYELRVQATDQGAS 652
Score = 72.5 bits (170), Expect = 8e-11
Identities = 79/290 (27%), Positives = 134/290 (46%), Gaps = 32/290 (11%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPY--HVTVD-ELTPTGEKA--FIFLIAPIGP 126
+G+ +S+ ++V V+I D NDN P L PY H +V+ E P +A F+ I +
Sbjct: 864 SGVPPLSSNVTVNVFILDENDNSPTIL-APYSEHGSVNSESIPYSAEAGYFVAKIRAVDA 922
Query: 127 S------LTIPLTVPRGLTIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
L+ L+ P+G +F+ +IR R N + +VS N D +
Sbjct: 923 DSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSA 982
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMA--SGKRIHKEILFPEPIHAIDQDLGVGATLR 232
S + V+++ D +F+ V M S ++ +L ++A D D G ++
Sbjct: 983 TVSIE-VVVVESAADIQT---QFRHVPMKEESFSDLNLYLLIAIVLNATDLDEGQNGKIK 1038
Query: 233 YELIS-GND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
Y I GN +F L+S G + ++ ELD + + + ++VQA+ ++A
Sbjct: 1039 YSFIKRGNSDPSNIFDLNSDTGEIKVKGELDYE-----ETPAYEVRVQANDQGTTPRSAH 1093
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
A++ IE++D NDN PE V + E+ G V + DKD G+NG
Sbjct: 1094 AKLLIEIIDENDNAPEISVTSLMTPLKEDAELGTIVALITVNDKDGGKNG 1143
Score = 71.7 bits (168), Expect = 1e-10
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 36/328 (10%)
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
N+ +R+ V DVND++P+F K+ Y V E + + ATD D G N L Y
Sbjct: 5 NLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSFAER 64
Query: 1088 DTDLP---FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
P F ++ G +++ G +D E Y + V ARD G DV
Sbjct: 65 GRFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKG-APPRTAHSKVLVEVIDV 123
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
NDN+P+ + L+ P ++ +V M+ + +N G T ++
Sbjct: 124 NDNAPEI-SVSSLMS---PVKEDAGLGT--AVAMVTINDRDGGKN---GLTNCRI-TGSV 173
Query: 1205 DFIGNGNGLILYSL-------PQRKNQQNL-------GLPSLSSTAILMVTVADVPDEVE 1250
F+ N YSL + +Q N+ G PSL+ T I+ V ++DV D
Sbjct: 174 PFMLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVND--- 230
Query: 1251 MSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNEN-DTDIRRTFV 1307
+ P F + ++EN V + V ++ ++ EN K Y++LN + + +
Sbjct: 231 --NPPRFPDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMIN 288
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
I+ G + ++S + E T++ V+A
Sbjct: 289 INSETGDIISLQSFNYEELKTFQFKVQA 316
Score = 70.9 bits (166), Expect = 2e-10
Identities = 54/187 (28%), Positives = 91/187 (48%), Gaps = 8/187 (4%)
Query: 218 IHAIDQDLGVGATLRYELIS-GN-DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
++A D D G LRY L+ GN + + FS+D +G + ++ LD + ++ + L+
Sbjct: 589 LNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIVVKASLDYE-----ESGAYELR 643
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA+ ++ ++V +E+LD+NDN PE V I E+ G V V TDKD
Sbjct: 644 VQATDQGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDG 703
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-KETNPSVVGTF 394
G+NG + ++ D + ++ +LDRE S + + A E P + T
Sbjct: 704 GQNGHLSCKIRDSSPFALKSNYKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTA 763
Query: 395 ADSQRIA 401
S +I+
Sbjct: 764 VISVQIS 770
Score = 70.1 bits (164), Expect = 4e-10
Identities = 64/219 (29%), Positives = 94/219 (42%), Gaps = 21/219 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +G TI+ L+A DLD G+NG++ Y F P E K F +N +G
Sbjct: 31 VVENANVGATILTLSATDLDDGVNGELVYSFAERGRFNP--------EDK--FALNAHNG 80
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
+ + ++ E + + + A D G +V V+ DVND+ P + V+
Sbjct: 81 EITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEVIDVNDNAPEISVSSLMSPVK 140
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLS--VNGELDRET 1112
E + V D D G+N I S +PF + S S V+G LDRET
Sbjct: 141 EDAGLGTAVAMVTINDRDGGKNGLTNCRITGS---VPFMLKSNYKNYYSLVVDGPLDRET 197
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +T+ A D G DVNDN P+F
Sbjct: 198 ASQYNVTITAEDEG-TPSLTGTTIINVQISDVNDNPPRF 235
Score = 67.3 bits (157), Expect = 3e-09
Identities = 78/324 (24%), Positives = 133/324 (41%), Gaps = 21/324 (6%)
Query: 218 IHAIDQDLGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D GV L Y N F+L++ NG + L+ +D + + + +
Sbjct: 44 LSATDLDDGVNGELVYSFAERGRFNPEDKFALNAHNGEITLKGNIDYE-----ENPAYEI 98
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+VQA P +TA ++V +E++D+NDN PE V + E+ G +V V D+D
Sbjct: 99 RVQARDKGAPPRTAHSKVLVEVIDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRD 158
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK-ETNPSVVGT 393
G+NG ++ + ++ LDRE S + + A+ E PS+ GT
Sbjct: 159 GGKNGLTNCRITGSVPFMLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGT 218
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
+ +I+ P L VG+ + D L LL+ +
Sbjct: 219 TIINVQISDVNDNPPRFPDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNS 278
Query: 454 DNNPVFVPSNLYE-----FSMKS--NAKVGTVIGKVKAVD---PDLGQNGMV-LYDLQRT 502
+ V N+ S++S ++ T KV+A D P L N V ++ L
Sbjct: 279 PKSGVAAMININSETGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDEN 338
Query: 503 SNL-TITSPFKINPNTGTVSVAES 525
N TI +P+ + + + S+ S
Sbjct: 339 DNSPTILAPYSEHGSVNSESIPYS 362
Score = 65.7 bits (153), Expect = 9e-09
Identities = 38/133 (28%), Positives = 73/133 (54%), Gaps = 10/133 (7%)
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+G Q+ I + D NDN P+F + Y+ ++EN+ +G I + ATD D+G N +Y
Sbjct: 3 SGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATIL---TLSATDLDDGVNGELVY 59
Query: 828 TLFGEGK----EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELII 881
+ G+ + F ++ + G + G ++D E+ Y++ + ARD G ++ +++++
Sbjct: 60 SFAERGRFNPEDKFALNAHNGEITLKG-NIDYEENPAYEIRVQARDKGAPPRTAHSKVLV 118
Query: 882 MIGDENDNKPEFN 894
+ D NDN PE +
Sbjct: 119 EVIDVNDNAPEIS 131
Score = 64.1 bits (149), Expect = 3e-08
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 7/105 (6%)
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
K+ ++ I ++D+NDN P F Y + +VEN G ++L + ATD D G NGE Y
Sbjct: 2 KSGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSF 61
Query: 346 DD-----PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ P+ F+++ +G +T++ +D E + + ++V A++
Sbjct: 62 AERGRFNPEDKFALNAHNGEITLKGN--IDYEENPAYEIRVQARD 104
Score = 58.0 bits (134), Expect = 2e-06
Identities = 80/277 (28%), Positives = 125/277 (45%), Gaps = 28/277 (10%)
Query: 436 DEQLMSFVNVEVTLLD-ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV-KAVDPDLGQNG 493
D L + V++EV +++ A D F + E S S+ + +I V A D D GQNG
Sbjct: 977 DPSLSATVSIEVVVVESAADIQTQFRHVPMKEESF-SDLNLYLLIAIVLNATDLDEGQNG 1035
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYS 551
+ Y + N ++ F +N +TG + V E A + V+A+DQ P
Sbjct: 1036 KIKYSFIKRGNSDPSNIFDLNSDTGEIKVKGELDYEETPAYEVRVQANDQGTTPRSAHAK 1095
Query: 552 LAVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYD 609
L + I+ N P+I + P + + +GT V I VND +N V+
Sbjct: 1096 LLIEIID----ENDNAPEISVTSLMTPLK----EDAELGTIVALITVNDKDGGKNGVAVC 1147
Query: 610 LLHGYEEGVPFAVEE--RSGVITVVDD-LSRYNRPMYDFEAVALQE-NANLSIVTNATVH 665
+ G VPF ++ ++ VVD L R N +Y+ A E + LS + TVH
Sbjct: 1148 KVVG---SVPFKLKSNYKNEYSLVVDGALDRENTSVYNVTVQATDEGDPPLSTIKVITVH 1204
Query: 666 VVDVNDERGVLLKGAHSPII-FHVKENS-AGAAIGQI 700
+ DVND V + P+I +++ENS G+ I I
Sbjct: 1205 ISDVNDNAPVFM----VPVINVYLRENSQTGSVIDTI 1237
Score = 56.4 bits (130), Expect = 6e-06
Identities = 57/208 (27%), Positives = 84/208 (40%), Gaps = 21/208 (10%)
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE 1010
I LNA DLD G NG+I+Y F PS + F +N G + V L E
Sbjct: 1022 IVLNATDLDEGQNGKIKYSFIKRGNSDPSNI----------FDLNSDTGEIKVKGELDYE 1071
Query: 1011 S--EFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
+ + + A D G + ++ ++ D ND+ P T ++E ++
Sbjct: 1072 ETPAYEVRVQANDQGTTPRSAHAKLLIEIIDENDNAPEISVTSLMTPLKEDAELGTIVAL 1131
Query: 1067 VDATDADFGQNANLTYFIQPSDTDLPFEIS---PLTGVLSVNGELDRETEDKYILTVVAR 1123
+ D D G+N + S +PF++ L V+G LDRE Y +TV A
Sbjct: 1132 ITVNDKDGGKNGVAVCKVVGS---VPFKLKSNYKNEYSLVVDGALDRENTSVYNVTVQAT 1188
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D G DVNDN+P F
Sbjct: 1189 DEG-DPPLSTIKVITVHISDVNDNAPVF 1215
Score = 54.4 bits (125), Expect = 2e-05
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+ A L Y L+ + + + VN + + L + + + TF +VQA+
Sbjct: 803 AQDADVNDNAKLTYSLLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQAT 862
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLP----NGFSVLQVMATDK 333
P ++ V + +LD NDN P + V E++P G+ V ++ A D
Sbjct: 863 DSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDA 922
Query: 334 DQGENGEFTYQLDDPKG 350
D G N +Y L +PKG
Sbjct: 923 DSGYNALLSYHLSEPKG 939
Score = 51.2 bits (117), Expect = 2e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 15/140 (10%)
Query: 221 IDQDLGVGATLRYELISGNDRK----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+D DL A Y L++ + + + +++S G + + L + + + TF +V
Sbjct: 260 LDSDLNENAKATYHLLNNSPKSGVAAMININSETGDI-----ISLQSFNYEELKTFQFKV 314
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLPN----GFSVLQVMA 330
QA+ P ++ V + +LD NDN P + V E++P G+ V ++ A
Sbjct: 315 QATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRA 374
Query: 331 TDKDQGENGEFTYQLDDPKG 350
D D G N +Y L +PKG
Sbjct: 375 VDADSGYNALLSYHLSEPKG 394
Score = 48.8 bits (111), Expect = 0.001
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 5/66 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVF-VPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
D L + + V + D NDN PVF VP N+Y ++ N++ G+VI + AVDPDL N
Sbjct: 1192 DPPLSTIKVITVHISDVNDNAPVFMVPVINVY---LRENSQTGSVIDTISAVDPDLDHNA 1248
Query: 494 MVLYDL 499
V+Y L
Sbjct: 1249 KVIYTL 1254
Score = 48.4 bits (110), Expect = 0.002
Identities = 40/182 (21%), Positives = 85/182 (46%), Gaps = 20/182 (10%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F I A+D D G A L Y L LF + + G + ++ + ++++L+ + V
Sbjct: 913 FVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRM---SDNDLKTHPLV 969
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA--- 330
+ V S +P +A +E+ +++ + + + F ++ + E + ++ ++A
Sbjct: 970 VLV--SDNGDPSLSATVSIEVVVVE---SAADIQTQFRHVPMKEESFSDLNLYLLIAIVL 1024
Query: 331 --TDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
TD D+G+NG+ Y DP F ++ +G + V+ + LD E + ++V A
Sbjct: 1025 NATDLDEGQNGKIKYSFIKRGNSDPSNIFDLNSDTGEIKVKGE--LDYEETPAYEVRVQA 1082
Query: 384 KE 385
+
Sbjct: 1083 ND 1084
Score = 46.0 bits (104), Expect = 0.008
Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 22/244 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++EV N A ++ + + E+ +GT + + D D G NG V
Sbjct: 117 LVEVIDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRDGGKNGLTNCRITGSV--- 173
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRV 1033
P L ++ K Y+ + +V L E S++ + I+A D G +L + V
Sbjct: 174 PFMLKSN---YKNYYSL-------VVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINV 223
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI----QPSDT 1089
+ DVND+ P F + N ++E + ++ D+D +NA TY + S
Sbjct: 224 QISDVNDNPPRFPDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGV 283
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
I+ TG + + E + V A D+G D NDNSP
Sbjct: 284 AAMININSETGDIISLQSFNYEELKTFQFKVQATDSG-VPPLSSNVTVNVFILDENDNSP 342
Query: 1150 KFYA 1153
A
Sbjct: 343 TILA 346
Score = 45.2 bits (102), Expect = 0.014
Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 13/167 (7%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+IE+ +N A ++ + + E+ +GT + + D D G NG + V
Sbjct: 1097 LIEIIDENDNAPEISVTSLMTPLKEDAELGTIVALITVNDKDGGKNGVAVCKVVGSV--- 1153
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFV 1035
P KL ++ NE V A S + + + A D G+ L+ + V +
Sbjct: 1154 PFKLKSNYK--------NEYSLVVDGALDRENTSVYNVTVQATDEGDPPLSTIKVITVHI 1205
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
DVND+ PVF N + E T V+ + A D D NA + Y
Sbjct: 1206 SDVNDNAPVFMVPVINVYLRENSQTGSVIDTISAVDPDLDHNAKVIY 1252
Score = 44.8 bits (101), Expect = 0.018
Identities = 23/72 (31%), Positives = 37/72 (51%)
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A+ P ++ A + +++ D+NDN P F + NI I EN G + + A D D
Sbjct: 749 IVATDEGTPPLSSTAVISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADV 808
Query: 336 GENGEFTYQLDD 347
+N + TY L D
Sbjct: 809 NDNAKLTYSLLD 820
Score = 43.6 bits (98), Expect = 0.043
Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 12/197 (6%)
Query: 150 DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIH 209
D TP +V V ND G S+H +L+ +++D + E + + + +
Sbjct: 1069 DYEETPAYEVR---VQANDQGTTP-RSAHAKLLI--EIIDENDNAPEISVTSLMTPLKED 1122
Query: 210 KEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQ 268
E+ I D+D G +++ KL S SL ++ LD +
Sbjct: 1123 AELGTIVALITVNDKDGGKNGVAVCKVVGSVPFKLKSNYKNEYSLVVDGALDRE-----N 1177
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ + + VQA+ +P + + + + D+NDN P F V N+ + EN G + +
Sbjct: 1178 TSVYNVTVQATDEGDPPLSTIKVITVHISDVNDNAPVFMVPVINVYLRENSQTGSVIDTI 1237
Query: 329 MATDKDQGENGEFTYQL 345
A D D N + Y L
Sbjct: 1238 SAVDPDLDHNAKVIYTL 1254
Score = 36.3 bits (80), Expect = 6.5
Identities = 18/47 (38%), Positives = 23/47 (48%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
L + G S L + V + DVNDN P+F + Y V V E P G
Sbjct: 537 LTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVPVG 583
>UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1210
Score = 134 bits (325), Expect = 1e-29
Identities = 136/501 (27%), Positives = 217/501 (43%), Gaps = 33/501 (6%)
Query: 402 KWRRQPLETNAPLE-KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV 460
KW + ++ N E K TYV KV + + S ++VT+ D NDN P+F
Sbjct: 167 KWPQLIVQQNLDREQKDTYVMKIKVE------DGGNPPKSSTAILQVTISDVNDNRPIFK 220
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV 520
S L E ++ NA +GT + ++ A D DLG N + + + F I+ +TG +
Sbjct: 221 DSEL-EVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSIDGSTGLI 279
Query: 521 SVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPY 578
+V +S L H L V ASD + PS + V + T + I G
Sbjct: 280 TVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPTIDTRYIINLVNGT-- 337
Query: 579 EFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE---ERSGVITVVDDL 635
+ N + T + I V D + D+ + + VPF ++ ++ L
Sbjct: 338 -VLLSENAPLNTKIALITVTD--KDADLYGKVACYTDHDVPFRLKPVFNDQFLLETAAPL 394
Query: 636 SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGA 695
Y + VA + + T+A V ++ + DE + I + EN+ +
Sbjct: 395 DYETTREYAIKIVA-SDRGTPPLNTSAMV-LIKIKDENDNVPIFPQPEIQLSIPENNDPS 452
Query: 696 AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRM 754
Q+ +S+ + N + D + + G + K LDREK+D Y
Sbjct: 453 T--QLI--KLSATDADSEHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREKQDRYAF 508
Query: 755 TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
TVIA+ N G S V + ++D NDN P F H Y ++ EN + + +I
Sbjct: 509 TVIAKDN-GSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTV---GLITV 564
Query: 815 TDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--G 872
TDAD G NA+ ++ GK+ F +D TGV+K + DRE++ Y + A D G
Sbjct: 565 TDADSGENAVVTLSIL-NGKDNFIIDPQTGVIK-PNITFDREQQSSYTFMVKAVDGGQPP 622
Query: 873 LSSEAELIIMIGDENDNKPEF 893
SS A++ I + D NDN+P F
Sbjct: 623 SSSYAKVTINVVDVNDNRPVF 643
Score = 125 bits (301), Expect = 1e-26
Identities = 131/501 (26%), Positives = 220/501 (43%), Gaps = 41/501 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+++ V + + D NDN P+F S + S+ N + T A DPD+G NG+
Sbjct: 87 DEIFRLVKIRFLIEDVNDNAPLF-QSTVINISIPENTAINTRYPVPSAFDPDVGINGIQH 145
Query: 497 YDLQRTSN---LTITSPFKINPNTGTVSVAESPILEGRHALFVEAS-DQPANPSERRYSL 552
Y+L ++ + L I + + V ++ E + ++ + NP + ++
Sbjct: 146 YELVKSVSEFGLDIIETPE-GDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAI 204
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDL 610
VTI + P F + E V N +GTSV Q+ DA + +
Sbjct: 205 LQVTISDVNDNR------PIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTF 258
Query: 611 LHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+ G F+++ +G+ITV L R P++ +A ++ S T V+V D
Sbjct: 259 SNQISAGTKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRAT-VIVNVTD 317
Query: 669 VND-----ERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSS-IYGNGTGNVRFLIA 721
VND + ++ + ++ + EN+ I I T+ + +YG +
Sbjct: 318 VNDNVPTIDTRYIINLVNGTVL--LSENAPLNTKIALITVTDKDADLYGKVACYTDHDVP 375
Query: 722 NQ-QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ + V +D + E T PLD E Y + ++A ++G V I I+DE
Sbjct: 376 FRLKPVFNDQFLLE-----TAAPLDYETTREYAIKIVAS-DRGTPPLNTSAMVLIKIKDE 429
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P+F + I EN+ T++ + ATDAD NA +YTL + E F+VD
Sbjct: 430 NDNVPIFPQPEIQLSIPENNDPSTQLIK---LSATDADSEHNAEIIYTLGPDAPEGFNVD 486
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEE 898
+GV+ +G LDREK+ Y +++A+D G L S + +++ D NDN P F E
Sbjct: 487 RRSGVLS-VGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEY 545
Query: 899 NSKVRIHRETKLNGTAGFTII 919
N + L GT G +
Sbjct: 546 N--FYVPENLPLFGTVGLITV 564
Score = 97.5 bits (232), Expect = 2e-18
Identities = 122/464 (26%), Positives = 195/464 (42%), Gaps = 60/464 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN I T +A D D G+NG YE V S+ D +E ++
Sbjct: 118 IPENTAINTRYPVPSAFDPDVGINGIQHYELVKSV----SEFGLDIIETPE----GDKWP 169
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+IV ++L E + + + I DGGN + ++V + DVND+ P+FK + V
Sbjct: 170 QLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFKDSELEVTVP 229
Query: 1056 EAQYTRRVLGKVDATDADFGQNANL--TYFIQPS-DTDLPFEISPLTGVLSVNGELDRET 1112
E + ++ ATDAD G NA + T+ Q S T F I TG+++V LDRE
Sbjct: 230 ENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSIDGSTGLITVKQSLDREL 289
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ L V+A D DVNDN P D L + N
Sbjct: 290 TPVHKLIVLASDG---SSTPSRATVIVNVTDVNDNVP---TIDTRYIINLVNGTVLLSEN 343
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDF----IGNGNGLILYSLPQ-------- 1220
I + T +++A + VA +D F + N L+ + P
Sbjct: 344 APLNTKIALITVT-DKDADLYGKVACYTDHDVPFRLKPVFNDQFLLETAAPLDYETTREY 402
Query: 1221 --RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
+ + G P L+++A++++ + D D V P+F +L I EN + +L+
Sbjct: 403 AIKIVASDRGTPPLNTSAMVLIKIKDENDNV-----PIFPQPEIQLSIPENNDPSTQLIK 457
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
L+ T+ + + I+ D F +D R+G L + + DRE +D Y V
Sbjct: 458 LSATD--ADSEHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREKQDRYAFTV----- 510
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
+A+D + +V V + ++D+NDNSP FT+
Sbjct: 511 ------------IAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTH 542
Score = 96.3 bits (229), Expect = 6e-18
Identities = 82/250 (32%), Positives = 111/250 (44%), Gaps = 21/250 (8%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
R T T+ +I++K +N Q IPEN T +IKL+A D DS N +
Sbjct: 411 RGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAE 470
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGG 1023
I Y L DA E F ++ R G + V + L E + R + A D G
Sbjct: 471 IIYT-----------LGPDAPEG---FNVDRRSGVLSVGKRLDREKQDRYAFTVIAKDNG 516
Query: 1024 N--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
+ L N++V++ V+D+ND+ P F YNF V E +G + TDAD G+NA +T
Sbjct: 517 STSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTVGLITVTDADSGENAVVT 576
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
I + F I P TGV+ N DRE + Y V A D G
Sbjct: 577 LSILNGKDN--FIIDPQTGVIKPNITFDREQQSSYTFMVKAVDGG-QPPSSSYAKVTINV 633
Query: 1142 XDVNDNSPKF 1151
DVNDN P F
Sbjct: 634 VDVNDNRPVF 643
Score = 89.4 bits (212), Expect = 7e-16
Identities = 117/461 (25%), Positives = 190/461 (41%), Gaps = 65/461 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P+GT++ +L+A D D G N QI + F++++ + KR+F I+ G
Sbjct: 228 VPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQI----------SAGTKRHFSIDGSTG 277
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV--- 1054
+ V +SL E +L + A DG + +V V V DVND+ P T Y N+
Sbjct: 278 LITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPTI-DTRYIINLVNG 336
Query: 1055 -----EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNG 1106
E A ++ + TD D + + +D D+PF + P+ +L
Sbjct: 337 TVLLSENAPLNTKI-ALITVTDKDADLYGKVACY---TDHDVPFRLKPVFNDQFLLETAA 392
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
LD ET +Y + +VA D G D NDN P F + ++ PE +
Sbjct: 393 PLDYETTREYAIKIVASDRG-TPPLNTSAMVLIKIKDENDNVPIFPQPE--IQLSIPENN 449
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
+ S ++ + A E NA I T+ + L + R+ Q
Sbjct: 450 DPST----QLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREKQDR 505
Query: 1227 LGLPSLS----STAILM-VTVADVPDEVEMSDKPVFISRYYELEIEENVN--APVELVSL 1279
++ ST++ VTV + ++ + P F Y + EN+ V L+++
Sbjct: 506 YAFTVIAKDNGSTSLQSNVTVKLIVQDLN-DNSPAFTHPEYNFYVPENLPLFGTVGLITV 564
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ EN + ILN D F+IDP+ G + + DRE + +Y +V+A
Sbjct: 565 TDADSGENAVVTLSILNGKD-----NFIIDPQTGVIKPNITFDREQQSSYTFMVKAVD-- 617
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ P Y KV + + DVNDN P F
Sbjct: 618 -GGQPPSSSY--------------AKVTINVVDVNDNRPVF 643
Score = 79.8 bits (188), Expect = 5e-13
Identities = 58/180 (32%), Positives = 96/180 (53%), Gaps = 14/180 (7%)
Query: 214 FPEPIHAIDQDLGVGATLRYELI-SGNDRKLFSLDSVNGSLF--LEKELDLDAEHNLQAN 270
+P P A D D+G+ YEL+ S ++ L +++ G + L + +LD E Q +
Sbjct: 128 YPVP-SAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRE---QKD 183
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
T+V++++ NP K++ A +++ + D+NDN P F+ +++ EN P G SV Q+ A
Sbjct: 184 TYVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHA 243
Query: 331 TDKDQGENGE--FTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
TD D G N + FT+ G FSID +G +TV+ LDRE ++ V A +
Sbjct: 244 TDADLGSNAQIHFTFSNQISAGTKRHFSIDGSTGLITVKQS--LDRELTPVHKLIVLASD 301
Score = 76.2 bits (179), Expect = 7e-12
Identities = 120/499 (24%), Positives = 202/499 (40%), Gaps = 53/499 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPS---NLYEFS--MKSNAKVGTVIGKVKAVDPDLGQNGMV 495
S V V + D NDN P NL + + NA + T I + D D G V
Sbjct: 307 SRATVIVNVTDVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKV 366
Query: 496 LYDLQRTSNLTITSPFKINP--NTGTVSVAESPI---LEGRHALFVEASDQPANPSERRY 550
PF++ P N + +P+ +A+ + ASD+ P
Sbjct: 367 ACYTDHDV------PFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLN--- 417
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
+ A+V I++ K ++P F + + N T + ++ DA +++
Sbjct: 418 TSAMVLIKI----KDENDNVPIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIY 473
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--D 668
G + F V+ RSGV++V L R + Y F +A ++N + S+ +N TV ++ D
Sbjct: 474 TLGPDAPEGFNVDRRSGVLSVGKRLDREKQDRYAFTVIA-KDNGSTSLQSNVTVKLIVQD 532
Query: 669 VNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ND H F+V EN +G I T+ S V I N +D
Sbjct: 533 LNDNSPAF---THPEYNFYVPENLPLFGTVGLITVTDADS---GENAVVTLSILNGKD-- 584
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I + G I DRE++ Y V A + G + +VTI + D NDN PVF
Sbjct: 585 NFIIDPQTGVIKPNITFDREQQSSYTFMVKA-VDGGQPPSSSYAKVTINVVDVNDNRPVF 643
Query: 788 --EHATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--------EGKEM 836
+ Y + N+ G + + A D D G NA Y++ + +
Sbjct: 644 VIPSSNYSYDLVRTNASPGAVVTR---VYAIDNDTGMNAELQYSIISSIIITSRVSPRGL 700
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F +D++TG + + + + + +++L + RD G S + ++ ND I
Sbjct: 701 FAIDKSTGNIT-LQEKIVAADQGLHRLVVKVRDLGQPESLHAITLVHLFVNDTVSNSTFI 759
Query: 897 EENSKVRIHRETKLNGTAG 915
+E ++R ET L+ G
Sbjct: 760 QE--QLRKSMETPLDRNIG 776
Score = 66.9 bits (156), Expect = 4e-09
Identities = 81/341 (23%), Positives = 138/341 (40%), Gaps = 42/341 (12%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE------------LTPTGE 114
+V G ++ V + I+D NDNVPIF +++ E T
Sbjct: 406 IVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLSIPENNDPSTQLIKLSATDADS 465
Query: 115 KAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
+ +I +GP V R + + DR+K D + V D+G +L
Sbjct: 466 EHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREK-----QDRYAFTVIAKDNGSTSL 520
Query: 175 ESSHKPVLLLRKVLDYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
+S+ L+++ + D E+ + + L I D D G A +
Sbjct: 521 QSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTVGL----ITVTDADSGENAVVT 576
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+++G D F +D G ++ + D E Q +++ V+A P ++ A+V
Sbjct: 577 LSILNGKDN--FIIDPQTG--VIKPNITFDRE---QQSSYTFMVKAVDGGQPPSSSYAKV 629
Query: 293 EIELLDLNDNLPEFEVDFYNIS---IVENLPNGFSVLQVMATDKDQGENGEFTYQL---- 345
I ++D+NDN P F + N S + N G V +V A D D G N E Y +
Sbjct: 630 TINVVDVNDNRPVFVIPSSNYSYDLVRTNASPGAVVTRVYAIDNDTGMNAELQYSIISSI 689
Query: 346 -----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
P+G F+ID +G +T++ + V + L +KV
Sbjct: 690 IITSRVSPRGLFAIDKSTGNITLQEKIVAADQGLHRLVVKV 730
Score = 66.5 bits (155), Expect = 5e-09
Identities = 93/357 (26%), Positives = 145/357 (40%), Gaps = 30/357 (8%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY- 102
+D + VK L + L+ + + + + +V V + DVNDNVP +DT Y
Sbjct: 272 IDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPT-IDTRYI 330
Query: 103 ------HVTVDELTPTGEKAFIFLIAPIGPSLTIPLT------VPRGLT-IFKDIRAFDR 149
V + E P K + + L + VP L +F D +
Sbjct: 331 INLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFNDQFLLET 390
Query: 150 DKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKR 207
P + Y+I + +D G L +S ++L K+ D + F Q I S
Sbjct: 391 AAPLDYETTREYAIKIVASDRGTPPLNTS---AMVLIKIKDENDNVPIFPQPEIQLSIPE 447
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHN 266
+ + A D D A + Y L G D + F++D +G L + K LD + +
Sbjct: 448 NNDPSTQLIKLSATDADSEHNAEIIYTL--GPDAPEGFNVDRRSGVLSVGKRLDREKQ-- 503
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
+ + V A + + V++ + DLNDN P F YN + ENLP +V
Sbjct: 504 ---DRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTVG 560
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ TD D GEN T + + K F IDP++G ++ DRE SS V A
Sbjct: 561 LITVTDADSGENAVVTLSILNGKDNFIIDPQTG--VIKPNITFDREQQSSYTFMVKA 615
Score = 66.1 bits (154), Expect = 7e-09
Identities = 54/166 (32%), Positives = 74/166 (44%), Gaps = 12/166 (7%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
N LE LD E + + +++ AS P A V I++ D NDN+P F
Sbjct: 383 NDQFLLETAAPLDYETTRE---YAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQP 439
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQT 367
+SI EN ++++ ATD D N E Y L D P+G F++D RSG L+V +
Sbjct: 440 EIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEG-FNVDRRSGVLSVGKR- 497
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP 413
LDRE V AK+ T S K Q L N+P
Sbjct: 498 -LDREKQDRYAFTVIAKDNG----STSLQSNVTVKLIVQDLNDNSP 538
Score = 57.2 bits (132), Expect = 3e-06
Identities = 104/464 (22%), Positives = 170/464 (36%), Gaps = 44/464 (9%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ +R ++DVND+ P+F+ T N ++ E A D D G N Y + S
Sbjct: 93 VKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSV 152
Query: 1089 TDLPFEI-----SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
++ +I L V LDRE +D Y++ + D G D
Sbjct: 153 SEFGLDIIETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGG-NPPKSSTAILQVTISD 211
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
VNDN P F D LE PE + SV + A + NA I T + +
Sbjct: 212 VNDNRPIFK--DSELEVTVPENAPMGT----SVAQLHATDADLGSNAQIHFTFSNQISAG 265
Query: 1204 TD---FIGNGNGLIL--YSLPQRKNQQNLGL------PSLSSTAILMVTVADVPDEVEMS 1252
T I GLI SL + + + S S A ++V V DV D V
Sbjct: 266 TKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPTI 325
Query: 1253 DKPVFISRYY-ELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPR 1311
D I+ + + EN ++ + +T+ + + ++D R V + +
Sbjct: 326 DTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFNDQ 385
Query: 1312 NGTLYLVRSPDREVKDTYEV-IVRAERQKYSRELPHMIYPVAEDVLEGMTKY-DVKVVVR 1369
L D E Y + IV ++R M+ +D + + + ++ +
Sbjct: 386 -FLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLS 444
Query: 1370 IKDVNDNSPKF---------TNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRA 1420
I + ND S + + N ++ + AP G+ V + G + R R
Sbjct: 445 IPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRSGVLS---VGKRLDRE 501
Query: 1421 DTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRF 1464
D F NG TS Q+ + + Q LN+ +P F
Sbjct: 502 KQDRYAFTVIAKDNGSTSLQS-----NVTVKLIVQDLNDNSPAF 540
Score = 50.4 bits (115), Expect = 4e-04
Identities = 78/353 (22%), Positives = 137/353 (38%), Gaps = 51/353 (14%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTV 134
++I + + IEDVNDN P+F T ++++ E T + + P + +
Sbjct: 87 DEIFRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPV----PSAFDPDVGING 142
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-KVLDYDAG 193
+ + K + F D TP D ++ + L+ K +++ KV D
Sbjct: 143 IQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQN-----LDREQKDTYVMKIKVEDGGNP 197
Query: 194 DKEFQLVIMAS------GKRIHK----EILFPE---------PIHAIDQDLGVGATLRYE 234
K ++ + + I K E+ PE +HA D DLG A + +
Sbjct: 198 PKSSTAILQVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFT 257
Query: 235 L---ISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
IS ++ FS+D G + +++ LD L H L VL S + P ++
Sbjct: 258 FSNQISAGTKRHFSIDGSTGLITVKQSLDRELTPVHKL----IVLASDGS--STP---SR 308
Query: 290 ARVEIELLDLNDNLPEFEVDFY------NISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
A V + + D+NDN+P + + + + EN P + + TDKD G+
Sbjct: 309 ATVIVNVTDVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVAC 368
Query: 344 QLDDPKGAFSIDP-RSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
D F + P + + LD E +K+ A + + T A
Sbjct: 369 YTDHDV-PFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSA 420
Score = 41.1 bits (92), Expect = 0.23
Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 12/167 (7%)
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
++ + D+NDN P F+ NISI EN A D D G NG Y+L
Sbjct: 94 KIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSVS 153
Query: 351 AFSID----PRSG-WLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIAKWR 404
F +D P W + Q LDRE + MK+ ++ NP T I+
Sbjct: 154 EFGLDIIETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDVN 213
Query: 405 -RQPLETNAPLEKTTYVFPDK--VGTKTENIEYYDEQLMSFVNVEVT 448
+P+ ++ LE T P+ +GT + D L S + T
Sbjct: 214 DNRPIFKDSELEVTV---PENAPMGTSVAQLHATDADLGSNAQIHFT 257
>UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type receptor
2 precursor; n=38; Euteleostomi|Rep: Cadherin EGF LAG
seven-pass G-type receptor 2 precursor - Homo sapiens
(Human)
Length = 2923
Score = 134 bits (324), Expect = 2e-29
Identities = 137/469 (29%), Positives = 213/469 (45%), Gaps = 41/469 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +V VT+LD NDNNP F Y + +A VGT + V AVD D + ++ Y
Sbjct: 590 LTASASVSVTVLDVNDNNPTFTQPE-YTVRLNEDAAVGTSVVTVSAVDRDA--HSVITYQ 646
Query: 499 LQRTSNLTITSPFKINPNTG--TVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
+ TS T + F I +G VS+A P+ LE ++ L V ASD R A
Sbjct: 647 I--TSGNT-RNRFSITSQSGGGLVSLA-LPLDYKLERQYVLAVTASDGT------RQDTA 696
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+ + VT P F + Y V + GT+V I D E + + +
Sbjct: 697 QIVVNVTDANTHR----PVFQSSHYTVNVNEDRPAGTTVVLISATD--EDTGENARITYF 750
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVN 670
E+ +P F ++ +G +T +L ++ Y A+ ++N S T + V DVN
Sbjct: 751 MEDSIPQFRIDADTGAVTTQAELDYEDQVSYTL-AITARDNGIPQKSDTTYLEILVNDVN 809
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D L+ ++ ++ ++ ++ QI T+ S G V + D D
Sbjct: 810 DNAPQFLRDSYQGSVY--EDVPPFTSVLQISATDRDS---GLNGRVFYTFQGGDDGDGDF 864
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ + G + T + LDRE Y + A +KG+ +VT+ + D NDNPPVFE
Sbjct: 865 IVESTSGIVRTLRRLDRENVAQYVLRAYA-VDKGMPPARTPMEVTVTVLDVNDNPPVFEQ 923
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKF 848
++ F+ ENS IG + + ATD DEGTNA MY + G E+F +D +G +
Sbjct: 924 DEFDVFVEENSPIGLAVAR---VTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTA 980
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ D LD E + Y L ++ + L S A + + + D NDN P E
Sbjct: 981 LVD-LDYEDRPEYVL-VIQATSAPLVSRATVHVRLLDRNDNPPVLGNFE 1027
Score = 128 bits (310), Expect = 9e-28
Identities = 128/477 (26%), Positives = 208/477 (43%), Gaps = 32/477 (6%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P F P + Y+ ++ N GT + ++A+DPD G+ G + Y + + F ++P
Sbjct: 179 PQFQPPS-YQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPV 237
Query: 517 TGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
TG V+ AE E + H V A D + RR +LA +TI V T N D P F
Sbjct: 238 TGAVTTAEELDRETKSTHVFRVTAQD---HGMPRRSALATLTILV---TDTNDHD-PVFE 290
Query: 575 GAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP---FAVEERSGVI 629
Y+ + N+ +G V +R DA ++ Y LL G G P F ++ RSGVI
Sbjct: 291 QQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEG-SGGSPSEVFEIDPRSGVI 349
Query: 630 TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
+ R Y A + + + + V D+ + + + V+
Sbjct: 350 RTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVR 409
Query: 690 ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKR 749
E+ A + S V + I + A+ G + PLD E
Sbjct: 410 EDVTPGA--PVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETT 467
Query: 750 DVYRMTVIA-EFNKGVISG-AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
Y + V A + + +S +G+ VT+ + D NDN P+F ++ ++E+ +G +
Sbjct: 468 KEYTLRVRAQDGGRPPLSNVSGL--VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVL 525
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
++A DAD G NA Y L G G + F ++ TG + + LDRE+ Y +
Sbjct: 526 H---VQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWIS-VAAELDREEVDFYSFGVE 581
Query: 867 ARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
ARD G L++ A + + + D NDN P F Q E VR++ + + GT+ T+ V
Sbjct: 582 ARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYT--VRLNEDAAV-GTSVVTVSAV 635
Score = 124 bits (299), Expect = 2e-26
Identities = 125/471 (26%), Positives = 198/471 (42%), Gaps = 38/471 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD NDN P+FV S ++ ++ + +G ++ V+A+D D G N + Y R +
Sbjct: 491 VTVQVLDINDNAPIFV-STPFQATVLESVPLGYLVLHVQAIDADAGDNARLEY---RLAG 546
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ PF IN TG +SVA E ++ VEA D S++V ++V
Sbjct: 547 VGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDN 606
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
P F Y + + +GTSV + D + ++Y + G F++
Sbjct: 607 N-------PTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRN-RFSI 658
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+SG V L + + + V+V D N R V + +H
Sbjct: 659 TSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPV-FQSSHY 717
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ + ++ AG + I T+ TG N R + + A+ G + TQ
Sbjct: 718 TVNVN-EDRPAGTTVVLISATD------EDTGENARITYFMEDSIPQFRIDADTGAVTTQ 770
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LD E + Y + + A N G+ + + I + D NDN P F +Y+G + E+
Sbjct: 771 AELDYEDQVSYTLAITARDN-GIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVP 829
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVKFIGDSLDREKKI 859
T + I ATD D G N YT G +G F V+ +G+V+ + LDRE
Sbjct: 830 PFTSVLQ---ISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTL-RRLDRENVA 885
Query: 860 MYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ------IEENSKV 902
Y L A D G + E+ + + D NDN P F Q +EENS +
Sbjct: 886 QYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPI 936
Score = 117 bits (282), Expect = 2e-24
Identities = 178/731 (24%), Positives = 298/731 (40%), Gaps = 104/731 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +++ D NDN P F Y ++ + G + +V A D D G N +V Y + +
Sbjct: 385 VFLSVEDDNDNAPQFSEKR-YVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGN- 442
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
F ++ TG + V SP+ + L V A D P L VT++V
Sbjct: 443 --ARGQFYLDAQTGALDVV-SPLDYETTKEYTLRVRAQDGGRPPLSNVSGL--VTVQVL- 496
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVPF 620
+ P F+ P++ V +V +G V ++ DA ++ + L G PF
Sbjct: 497 ---DINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPF 553
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKG 679
+ +G I+V +L R Y F A L+ + +V V+DVND +
Sbjct: 554 TINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQP 613
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA--NQQDVTDDIAIAEDGT 737
++ V+ N AA+G T +S++ + + + I N ++ + + G
Sbjct: 614 EYT-----VRLNE-DAAVGTSVVT-VSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGL 666
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ PLD + Y + V A + G Q+ + + D N + PVF+ + Y +
Sbjct: 667 VSLALPLDYKLERQYVLAVTA--SDGTRQDTA--QIVVNVTDANTHRPVFQSSHYTVNVN 722
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
E+ GT + + I ATD D G EN + F+ DS+ + +
Sbjct: 723 EDRPAGTTVVL---ISATDEDTG--------------------ENARITYFMEDSIPQFR 759
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
+ DTG ++++AEL D D Q+ + R+ + + T
Sbjct: 760 --------IDADTGAVTTQAEL-----DYED------QVSYTLAITA-RDNGIPQKSDTT 799
Query: 918 IIEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+E+ DV+ P FL + E++P T++++++A D DSGLNG++ Y F
Sbjct: 800 YLEI-----LVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTF 854
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LN 1026
D F++ G V R L E+ ++ L A+D G
Sbjct: 855 QGG-----DDGDGD-------FIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPAR 902
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+ V V V DVND+ PVF++ ++ VEE + +V ATD D G NA + Y I
Sbjct: 903 TPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVE 962
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ F++ +G L+ +LD E +Y+L + A D ND
Sbjct: 963 GNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQA----TSAPLVSRATVHVRLLDRND 1018
Query: 1147 NSPKFYAFDEL 1157
N P F+ L
Sbjct: 1019 NPPVLGNFEIL 1029
Score = 106 bits (254), Expect = 5e-21
Identities = 116/432 (26%), Positives = 188/432 (43%), Gaps = 59/432 (13%)
Query: 929 LDVDQLGPLFLIPE-------NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P F PE + +GT+++ ++A+D D+ + I Y+ S
Sbjct: 601 LDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVITYQITSG-------- 650
Query: 982 SADALEVKRYFVINERHGHVIVARSLPP----ESEFRLNISALDGGNLNDNISVRVFVKD 1037
+ F I + G +V+ +LP E ++ L ++A DG D + V V D
Sbjct: 651 -----NTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTR-QDTAQIVVNVTD 704
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
N H PVF+ + Y NV E + + + ATD D G+NA +TYF++ D+ F I
Sbjct: 705 ANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME--DSIPQFRIDA 762
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
TG ++ ELD E + Y L + ARDNG DVNDN+P+F D
Sbjct: 763 DTGAVTTQAELDYEDQVSYTLAITARDNG-IPQKSDTTYLEILVNDVNDNAPQFLR-DSY 820
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+ + F SV+ I N + T D DFI I+ +
Sbjct: 821 QGSVYEDVPP-----FTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRT 875
Query: 1218 LPQRKNQQNL------------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
L +R +++N+ G+P + + VTV DV D + PVF +++
Sbjct: 876 L-RRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVND-----NPPVFEQDEFDVF 929
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+EEN + + + T+ E N ++ Y I+ N I F +D +G L + D
Sbjct: 930 VEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGN---IPEVFQLDIFSGELTALVDLDY 986
Query: 1324 EVKDTYEVIVRA 1335
E + Y ++++A
Sbjct: 987 EDRPEYVLVIQA 998
Score = 99.5 bits (237), Expect = 6e-19
Identities = 126/488 (25%), Positives = 203/488 (41%), Gaps = 59/488 (12%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
R+ T + V+ N A + + + E++ G ++++ A D D G N
Sbjct: 374 RDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDKGSNAV 433
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG 1023
+ Y S +S +A + F ++ + G + V L E+ E+ L + A DGG
Sbjct: 434 VHY----------SIMSGNA---RGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGG 480
Query: 1024 NLN-DNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
N+S V V V D+ND+ P+F T + V E+ ++ V A DAD G NA L
Sbjct: 481 RPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARL 540
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y + D PF I+ TG +SV ELDRE D Y V ARD+G
Sbjct: 541 EYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHG-TPALTASASVSVT 599
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF 1200
DVNDN+P F PE N + +V V + ++ +A T
Sbjct: 600 VLDVNDNNPTF---------TQPEYTVRLNED-AAVGTSVVTVSAVDRDAHSVITYQITS 649
Query: 1201 ANDTDFIG----NGNGLILYSLP-QRKNQQNLGLPSLSSTAILMVTVADVPDEVEM-SDK 1254
N + +G GL+ +LP K ++ L +S T V + + + +
Sbjct: 650 GNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHR 709
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRN 1312
PVF S +Y + + E+ A +V ++ T+ EN ++ Y++ D F ID
Sbjct: 710 PVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFM-----EDSIPQFRIDADT 764
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
G + D E + +Y + + A +P + T Y + + + D
Sbjct: 765 GAVTTQAELDYEDQVSYTLAITAR----DNGIPQ----------KSDTTY---LEILVND 807
Query: 1373 VNDNSPKF 1380
VNDN+P+F
Sbjct: 808 VNDNAPQF 815
Score = 95.5 bits (227), Expect = 1e-17
Identities = 86/319 (26%), Positives = 145/319 (45%), Gaps = 36/319 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTP--------------TGEKAFI-FLIAPIGPS 127
VTV + D+NDN PIF+ TP+ TV E P G+ A + + +A +G
Sbjct: 491 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHD 550
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
P T+ G DR++ D + V D G AL +S + + V
Sbjct: 551 F--PFTINNGTGWISVAAELDREEV-----DFYSFGVEARDHGTPALTASASVSVTVLDV 603
Query: 188 LDYDAGDKEFQLVI-MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
D + + + + + + ++ + A+D+D + + Y++ SGN R FS+
Sbjct: 604 NDNNPTFTQPEYTVRLNEDAAVGTSVV---TVSAVDRD--AHSVITYQITSGNTRNRFSI 658
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
S +G + L LD + Q +VL V AS + + A++ + + D N + P F
Sbjct: 659 TSQSGGGLVSLALPLDYKLERQ---YVLAVTAS---DGTRQDTAQIVVNVTDANTHRPVF 712
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
+ Y +++ E+ P G +V+ + ATD+D GEN TY ++D F ID +G V Q
Sbjct: 713 QSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTG--AVTTQ 770
Query: 367 TVLDREAHSSLRMKVYAKE 385
LD E S + + A++
Sbjct: 771 AELDYEDQVSYTLAITARD 789
Score = 87.4 bits (207), Expect = 3e-15
Identities = 62/176 (35%), Positives = 85/176 (48%), Gaps = 15/176 (8%)
Query: 218 IHAIDQDLGVGATLRYE---LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ AID D G L Y L + FSLD V G++ +ELD + + +T V
Sbjct: 203 LRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDRETK-----STHVF 257
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+V A P ++A A + I + D ND+ P FE Y S+ ENL G+ VL V ATD D
Sbjct: 258 RVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGD 317
Query: 335 QGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y+L P F IDPRSG +R + +DRE S ++ V A +
Sbjct: 318 APPNANILYRLLEGSGGSPSEVFEIDPRSG--VIRTRGPVDREEVESYQLTVEASD 371
Score = 86.2 bits (204), Expect = 6e-15
Identities = 115/460 (25%), Positives = 191/460 (41%), Gaps = 56/460 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P GT + L A+D D G G++ Y ++ + S+ + ++F ++ G
Sbjct: 190 VPENQPAGTPVASLRAIDPDEGEAGRLEYTMDA---LFDSRSN-------QFFSLDPVTG 239
Query: 1000 HVIVARSLPPESEFR--LNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V A L E++ ++A D G + ++ + V D NDH PVF++ Y ++
Sbjct: 240 AVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLR 299
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP---FEISPLTGVLSVNGELDRET 1112
E + V ATD D NAN+ Y + P FEI P +GV+ G +DRE
Sbjct: 300 ENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPVDREE 359
Query: 1113 EDKYILTVVARDNGXX-XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH---PEADEL 1168
+ Y LTV A D G D NDN+P+F +++ + P A L
Sbjct: 360 VESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVL 419
Query: 1169 --SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
+ + + V+ + + NA G D + + R Q+
Sbjct: 420 RVTASDRDKGSNAVVHYSIMSGNAR-GQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQD 478
Query: 1227 LGLPSLSS-TAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL---- 1281
G P LS+ + ++ V V D+ D + P+F+S ++ + E+V P+ + L++
Sbjct: 479 GGRPPLSNVSGLVTVQVLDIND-----NAPIFVSTPFQATVLESV--PLGYLVLHVQAID 531
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
+ +N ++ Y + D F I+ G + + DRE D Y V A
Sbjct: 532 ADAGDNARLEYRLAGVGH-DF--PFTINNGTGWISVAAELDREEVDFYSFGVEAR----- 583
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ +T V V + DVNDN+P FT
Sbjct: 584 -----------DHGTPALTA-SASVSVTVLDVNDNNPTFT 611
Score = 86.2 bits (204), Expect = 6e-15
Identities = 66/236 (27%), Positives = 109/236 (46%), Gaps = 13/236 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A + Y ++SGN R F LD+ G+L + LD + + L+V+
Sbjct: 421 VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYET-----TKEYTLRVR 475
Query: 278 ASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P L V +++LD+NDN P F + +++E++P G+ VL V A D D G
Sbjct: 476 AQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAG 535
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+N Y+L F+I+ +GW++V + LDRE V A++ P++ +
Sbjct: 536 DNARLEYRLAGVGHDFPFTINNGTGWISVAAE--LDREEVDFYSFGVEARDHGTPALTAS 593
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPD-KVGTKTENIEYYDEQLMSFVNVEVT 448
+ S + P E T + D VGT + D S + ++T
Sbjct: 594 ASVSVTVLDVNDNNPTFTQP-EYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQIT 648
Score = 79.0 bits (186), Expect = 9e-13
Identities = 57/169 (33%), Positives = 88/169 (52%), Gaps = 12/169 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+D G A + Y + + F +D+ G++ + ELD + + + + L +
Sbjct: 734 ISATDEDTGENARITYFMEDSIPQ--FRIDADTGAVTTQAELDYEDQVS-----YTLAIT 786
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K+ +EI + D+NDN P+F D Y S+ E++P SVLQ+ ATD+D G
Sbjct: 787 ARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGL 846
Query: 338 NGE--FTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG +T+Q DD G F ++ SG VR LDRE + ++ YA
Sbjct: 847 NGRVFYTFQGGDDGDGDFIVESTSG--IVRTLRRLDRENVAQYVLRAYA 893
Score = 74.5 bits (175), Expect = 2e-11
Identities = 80/332 (24%), Positives = 137/332 (41%), Gaps = 23/332 (6%)
Query: 44 VDSDSPQNVVKFRLGCDFD-EGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
+ S S +V L D+ E ++ + A + V + D N + P+F + Y
Sbjct: 658 ITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSHY 717
Query: 103 HVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTIFK---DIRAFDRDKPNTPNS 157
V V+E P G + G + I + + F+ D A
Sbjct: 718 TVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYED 777
Query: 158 DVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL-FP 215
V Y++ ++ D+G K ++L D D Q + + +++++ F
Sbjct: 778 QVSYTLAITARDNG-----IPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFT 832
Query: 216 E--PIHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I A D+D G+ + Y G+D F ++S +G + + LD + +
Sbjct: 833 SVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRE-----NVAQY 887
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VL+ A P V + +LD+NDN P FE D +++ + EN P G +V +V ATD
Sbjct: 888 VLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATD 947
Query: 333 KDQGENGEFTYQLDDPK--GAFSIDPRSGWLT 362
D+G N + YQ+ + F +D SG LT
Sbjct: 948 PDEGTNAQIMYQIVEGNIPEVFQLDIFSGELT 979
Score = 70.1 bits (164), Expect = 4e-10
Identities = 97/383 (25%), Positives = 159/383 (41%), Gaps = 53/383 (13%)
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLT 1099
P F+ Y V E Q + + A D D G+ L Y + S ++ F + P+T
Sbjct: 179 PQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVT 238
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
G ++ ELDRET+ ++ V A+D+G D ND+ P F E E
Sbjct: 239 GAVTTAEELDRETKSTHVFRVTAQDHG-MPRRSALATLTILVTDTNDHDPVF----EQQE 293
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPI--------GTTVAKVFAND-TDFIGNG 1210
+K + L +E V+ + NA I G + ++VF D +
Sbjct: 294 YKESLRENL-EVGYE-VLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351
Query: 1211 NGLI------LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
G + Y L + Q S+TA + ++V D D + P F + Y +
Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDND-----NAPQFSEKRYVV 406
Query: 1265 EIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
++ E+V APV V+ + + N + Y I++ N R F +D + G L +V D
Sbjct: 407 QVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGN---ARGQFYLDAQTGALDVVSPLD 463
Query: 1323 REVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
E Y + VRA Q R P++ + G+ V V++ D+NDN+P F
Sbjct: 464 YETTKEYTLRVRA--QDGGRP------PLSN--VSGL------VTVQVLDINDNAPIFV- 506
Query: 1383 GNRPLVTAIPTTAPFGYQVMQLK 1405
+ P + + P GY V+ ++
Sbjct: 507 -STPFQATVLESVPLGYLVLHVQ 528
Score = 60.9 bits (141), Expect = 3e-07
Identities = 48/175 (27%), Positives = 88/175 (50%), Gaps = 14/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D A + Y L+ G+ ++F +D +G + +D + + ++ L
Sbjct: 311 VRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPVDRE-----EVESYQL 365
Query: 275 QVQAS-QLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V+AS Q +P ++ A V + + D NDN P+F Y + + E++ G VL+V A+D
Sbjct: 366 TVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASD 425
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+D+G N Y + + +G F +D ++G L V + LD E ++V A++
Sbjct: 426 RDKGSNAVVHYSIMSGNARGQFYLDAQTGALDV--VSPLDYETTKEYTLRVRAQD 478
Score = 51.6 bits (118), Expect = 2e-04
Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 14/132 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y+++ GN ++F LD +G L +DLD E + +VL +Q
Sbjct: 943 VTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGE--LTALVDLDYEDRPE---YVLVIQ 997
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLP---EFEVDF--YNISIVENLPNGFSVLQVMATD 332
A+ + PL ++A V + LLD NDN P FE+ F Y + + P G ++ +V A D
Sbjct: 998 AT--SAPL-VSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGG-AIGRVPAHD 1053
Query: 333 KDQGENGEFTYQ 344
D ++ ++++
Sbjct: 1054 PDISDSLTYSFE 1065
Score = 48.4 bits (110), Expect = 0.002
Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKG--AFSIDPRS 358
P+F+ Y ++ EN P G V + A D D+GE G Y +D D + FS+DP +
Sbjct: 179 PQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVT 238
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +T + LDRE S+ +V A++
Sbjct: 239 GAVTTAEE--LDRETKSTHVFRVTAQD 263
Score = 39.5 bits (88), Expect = 0.69
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 10/91 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF----VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
L+S V V LLD NDN PV + N Y + +S++ G IG+V A DPD+ +
Sbjct: 1003 LVSRATVHVRLLDRNDNPPVLGNFEILFNNY-VTNRSSSFPGGAIGRVPAHDPDISDS-- 1059
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
+ Y +R + L++ +N +TG + ++ +
Sbjct: 1060 LTYSFERGNELSLV---LLNASTGELKLSRA 1087
Score = 36.7 bits (81), Expect = 4.9
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 144 IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMA 203
+ A DRDK + N+ VHYSI+SGN G F L+ + L + LDY+ KE+ L + A
Sbjct: 421 VTASDRDKGS--NAVVHYSIMSGNARGQFYLD-AQTGALDVVSPLDYET-TKEYTLRVRA 476
>UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1610
Score = 133 bits (322), Expect = 3e-29
Identities = 137/482 (28%), Positives = 205/482 (42%), Gaps = 31/482 (6%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN--AKVGTVIGKVKAVDP 487
E I++ L V V VT+ + NDN P F N Y F + A ++G V A D
Sbjct: 724 EVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDN-YTFWISEGDFAVDHAIVGVVSAHDL 782
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSE 547
D + L + + T PF I+ +TG + S EG Q + P+
Sbjct: 783 DADSSNCPLCGKLQYTLGNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNR 842
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQND 605
++ +VT+ + N D P F Y V + G +V +IR ND +
Sbjct: 843 PLVNVTMVTVNL---LDVNDND-PVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNAN 898
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATV 664
VSY ++ G G F V+ +G I +V L R Y + A T +
Sbjct: 899 VSYSIVSG-NTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVII 957
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+V+DVND V L H + EN AG + ++ T+ ++ G V + + +
Sbjct: 958 YVMDVNDNSPVCL---HDTQTVRLLENLPAGHFVVKVVTTDPDEVH---NGRVEYNLTSD 1011
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D G I T + LDRE Y + V A N V + + D ND+
Sbjct: 1012 AFRVDPFT----GIITTTRALDRESIPAYNLMVTAR-NSNSSDMEVNCSVHVIVMDTNDH 1066
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F A Y E + +G+ + ++A D D+G NA YTL GE + +F ++ T
Sbjct: 1067 TPSFTMARYYISTPETTPVGSTLFR---VRAVDGDDGINAEVRYTLMGE-ESLFRINYTT 1122
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE---LIIMIGDENDNKPEFNQIEENS 900
G+V + SLDRE K Y+L + ARD G S A ++I +GD NDN+P F +
Sbjct: 1123 GIVTLV-SSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDG 1181
Query: 901 KV 902
V
Sbjct: 1182 NV 1183
Score = 129 bits (311), Expect = 7e-28
Identities = 209/850 (24%), Positives = 346/850 (40%), Gaps = 95/850 (11%)
Query: 511 FKINPNTGTVSVAESPILEG--RHALFVEASDQPAN----PSERRYSLAVVTIEVTRGTK 564
F I+ N G + +A E ++ L + AS+ N P + +VT+ V
Sbjct: 158 FDIDFNKGVIRLARELDFEQMTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVL---- 213
Query: 565 GNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFA 621
+ D+P F Y + N +G+ V Q+ D + + V+Y + F
Sbjct: 214 -DADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFN 272
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ +G IT+ L R Y +A T + V DVND + ++
Sbjct: 273 IANITGEITLNGSLDRETIAEYRLRILAYC--TIYQDHTEVLITVTDVNDNIPLFTLPSY 330
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ V EN AAIG + G N F+ + + G I
Sbjct: 331 NTT---VNEN---AAIGTYVIQVQAEDIDQGV-NASFIYEIAYAGHEFVIGEHSGIIIVN 383
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LDREK+D+Y +TVIA + +T+ + DENDN P+F A Y I EN
Sbjct: 384 GTLDREKKDLYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEP 443
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVKFIGDSLDREKK 858
GT + + A D+D G+NA+ Y + + + + F ++ G + LDRE
Sbjct: 444 PGTFVIQ---VSANDSDIGSNAMVSYAVLSDAEGHYQYFKINAKNGTIT-TSRRLDRENI 499
Query: 859 IMYKLSLVARDTGGLS----SEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
++L + A D LS S ++++ + D NDN PEF + N V ET L G A
Sbjct: 500 TTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSV---IETALPG-A 555
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
II ++K D++ +++I E G+ II SGL Q+ + + EV
Sbjct: 556 ILGIISAVDRDK---DLNG-NIVYIITEGNVEGSFIIGAR-----SGLL-QLNHTLDREV 605
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF 1034
+S +L V ++R G EF + S+L N I+V +
Sbjct: 606 ------VSKHSLRV----TASDRGG------------EFMADGSSL-----NTTINVTIN 638
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V D ND+ PV K +Y ++ E + L ++ TD D G+NA+L Y + + F
Sbjct: 639 VLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMVSGHS--KFV 696
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
+ +TG++S+N LD E + + + +VNDN P F
Sbjct: 697 VDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSF-GQ 755
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNG 1212
D W E D +H V+ A N P+ + N T I G
Sbjct: 756 DNYTFW-ISEGDFAVDHAIVGVVSAHDLDAD-SSNCPLCGKLQYTLGNSTGPFAIDKDTG 813
Query: 1213 LI--LYSLPQR--KNQ--QNLGLPSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELE 1265
++ + SL + KN + S+ + ++ VT+ V + ++++D PVF Y
Sbjct: 814 VLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTV-NLLDVNDNDPVFDRDVYTAN 872
Query: 1266 IEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+ E+ + + ++ + ++ N + Y I++ N F +D G + LV +R
Sbjct: 873 VSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGN---TGAAFHVDNVTGEIKLVSKLER 929
Query: 1324 EVKDTYEVIV 1333
E +Y + V
Sbjct: 930 EKITSYTLTV 939
Score = 128 bits (310), Expect = 9e-28
Identities = 127/462 (27%), Positives = 209/462 (45%), Gaps = 23/462 (4%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+S V+V VT+LD NDN+P FV + Y FS+ A G ++G + AVD D NG ++Y +
Sbjct: 519 VSVVDVVVTVLDINDNSPEFVRPS-YNFSVIETALPGAILGIISAVDRDKDLNGNIVYII 577
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
+ + F I +G + + + E +H+L V ASD+ SL TI
Sbjct: 578 TEGN---VEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLN-TTI 633
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
VT + +IP Y + N +G S+ + D + + ++ L H
Sbjct: 634 NVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQ-DSGENAHLLYHMVSGH 692
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGV 675
F V+ +G++++ L +P A+ + ++ LS+V V V +VND
Sbjct: 693 SKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPS 752
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG--TGNVRFLIANQQDVTDDIAIA 733
+ ++ I A +G + ++ + N G +++ + N T AI
Sbjct: 753 FGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTLGNS---TGPFAID 809
Query: 734 ED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+D G + LDRE Y +VIA+ + + VT+ + D NDN PVF+ Y
Sbjct: 810 KDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVY 869
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+ E++ G + I+A D D +NA Y++ G F VD TG +K +
Sbjct: 870 TANVSEDASPGLTVLK---IRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEIKLV-S 925
Query: 852 SLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKP 891
L+REK Y L++ + D G + S A +II + D NDN P
Sbjct: 926 KLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSP 967
Score = 120 bits (289), Expect = 3e-25
Identities = 125/461 (27%), Positives = 198/461 (42%), Gaps = 32/461 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V V ++D ND+ P F + Y S VG+ + +V+AVD D G N V Y L
Sbjct: 1055 SVHVIVMDTNDHTPSFTMARYY-ISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGEE 1113
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
+L F+IN TG V++ S E + + L VEA D+ S + ++ +
Sbjct: 1114 SL-----FRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVN 1168
Query: 562 GTKGNKPDIPDFMGAPYEFWV-GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ P F A Y+ V VG ++ D D+ Y ++ G + F
Sbjct: 1169 DNR------PTFTHAHYDGNVLEGQVGAVAAIVVALDKDEEINADIVYSIIGGNTDN-SF 1221
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKG 679
A+ +SG I + L R Y +A ++ TN T+HV DVND + +
Sbjct: 1222 AINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNI--- 1278
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
++P + +EN+ G + + +S G+ N R + +I +G I
Sbjct: 1279 TNNPGVVVTRENTPP---GSLVYILSASDLDEGS-NARVAFSGYAVPDGKFSIKPNGEIM 1334
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+ LDRE ++ + +A + + + I I DENDN PVF+ Y I EN
Sbjct: 1335 VRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISEN 1394
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
G ++ + A++ DEG LF + G+ F + TGV+ LDRE
Sbjct: 1395 ---GPSEEVIVQVNASERDEG-KLLFKIS-SGDPGGYFTIHNVTGVIS-TRKPLDREMVS 1448
Query: 860 MYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFNQIEE 898
+ L++ A D G S A + I + DEND P Q E+
Sbjct: 1449 RFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQ 1489
Score = 115 bits (276), Expect = 1e-23
Identities = 129/485 (26%), Positives = 212/485 (43%), Gaps = 43/485 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L++ V V LLD NDN+PVF ++Y ++ +A G + K++AVD DL N V Y
Sbjct: 844 LVNVTMVTVNLLDVNDNDPVF-DRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYS 902
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
+ S T + F ++ TG + + E + L V ++D A P R S A+V
Sbjct: 903 I--VSGNT-GAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVP---RRSTALVI 956
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGY 614
I V + + D + N+ G V ++ D E ++ V Y+L
Sbjct: 957 IYVMDVNDNSPVCLHDTQTVR----LLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSD- 1011
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDE 672
F V+ +G+IT L R + P Y+ A N++ + N +VHV+ D ND
Sbjct: 1012 ----AFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNSS-DMEVNCSVHVIVMDTNDH 1066
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+++ +F VR+ + ++ +
Sbjct: 1067 TPSFTMAR-----YYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGEESLFR--IN 1119
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI-SGAGIYQVTIYIEDENDNPPVFEHAT 791
G + LDRE + Y++ V A ++G+ S A + I + D NDN P F HA
Sbjct: 1120 YTTGIVTLVSSLDRENKAQYQLEVEAR-DRGIPESNANSTTILIRVGDVNDNRPTFTHAH 1178
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIG 850
Y+G ++E ++G + I+ A D DE NA +Y++ G + F ++ +G + +
Sbjct: 1179 YDGNVLE-GQVGA---VAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSGSI-YTL 1233
Query: 851 DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
LDRE Y L+++A D G ++S + I + D NDNKP I N V + RE
Sbjct: 1234 LHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKP---NITNNPGVVVTREN 1290
Query: 909 KLNGT 913
G+
Sbjct: 1291 TPPGS 1295
Score = 111 bits (266), Expect = 2e-22
Identities = 127/468 (27%), Positives = 201/468 (42%), Gaps = 40/468 (8%)
Query: 445 VEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
V +T+ D NDN P+F +PS Y ++ NA +GT + +V+A D D G N +Y++
Sbjct: 311 VLITVTDVNDNIPLFTLPS--YNTTVNENAAIGTYVIQVQAEDIDQGVNASFIYEIAYAG 368
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F I ++G + V + E + + + S +S +T+ + R
Sbjct: 369 H-----EFVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFHSNVTITV-MLRDE 422
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP-F 620
N P F A Y + N GT V Q+ ND+ ++ VSY +L E F
Sbjct: 423 NDNS---PIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHYQYF 479
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI----VTNATVHVVDVNDERGVL 676
+ ++G IT L R N + A + A LS V + V V+D+ND
Sbjct: 480 KINAKNGTITTSRRLDRENITTFRLRVTA-SDGAPLSTIRVSVVDVVVTVLDINDNSPEF 538
Query: 677 LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
++ +++ F V E + GA +G I + + GN+ ++I I A
Sbjct: 539 VRPSYN---FSVIETALPGAILGIISAVDRDK---DLNGNIVYIITEGNVEGSFIIGARS 592
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG-----IYQVTIYIEDENDNPPVFEHA 790
G + LDRE + + V A G G VTI + D NDN PV +
Sbjct: 593 GLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKV 652
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
Y I EN+ +G + + TD D G NA +Y + G F VD TG++ +
Sbjct: 653 YYTISIPENTSVGQSLIH---LNCTDQDSGENAHLLYHMV-SGHSKFVVDNVTGIMS-LN 707
Query: 851 DSLD-REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LD EK ++ +++ D G LS + + + + NDN P F Q
Sbjct: 708 KLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQ 755
Score = 110 bits (264), Expect = 3e-22
Identities = 129/468 (27%), Positives = 201/468 (42%), Gaps = 39/468 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +NV + +LD+NDN PV Y S+ N VG + + D D G+N +LY
Sbjct: 629 LNTTINVTINVLDSNDNIPV-CDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYH 687
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ ++ S F ++ TG +S+ + E + +F A + + SL VV +
Sbjct: 688 M-----VSGHSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEV-IDHGRPPLSL-VVFVN 740
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWV--GSNVGIGTSVGQIRVND--AFEQN-----DVSYD 609
VT + + P F Y FW+ G VG + +D A N + Y
Sbjct: 741 VTVDNVND--NYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYT 798
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE--NANLSIVTNATVHVV 667
L G G PFA+++ +GV+ V L R Y F +A N L VT TV+++
Sbjct: 799 L--GNSTG-PFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLL 855
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
DVND V + ++ + ++ S G + +I + + + N NV + I +
Sbjct: 856 DVNDNDPVFDRDVYTANVS--EDASPGLTVLKIRAVD-NDLASNA--NVSYSIVSGNTGA 910
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G I L+REK Y +TV + G + V IY+ D NDN PV
Sbjct: 911 AFHVDNVTGEIKLVSKLEREKITSYTLTV-GSADGGAVPRRSTALVIIYVMDVNDNSPVC 969
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
H T ++EN G + + TD DE N Y L + F VD TG++
Sbjct: 970 LHDTQTVRLLENLPAGHFVVK---VVTTDPDEVHNGRVEYNLTSDA---FRVDPFTGIIT 1023
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEF 893
+LDRE Y L + AR++ E + +++ D ND+ P F
Sbjct: 1024 -TTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSF 1070
Score = 104 bits (250), Expect = 2e-20
Identities = 119/441 (26%), Positives = 188/441 (42%), Gaps = 41/441 (9%)
Query: 911 NGTAGFTIIEVKPKNKFALDV--DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
NG + +T++ V + L V + IPEN +G+ +++++A DLD +N + Y
Sbjct: 200 NGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTY 259
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLN 1026
+ E R F I G + + SL E+ E+RL I A
Sbjct: 260 AIDKET------------NPLRMFNIANITGEITLNGSLDRETIAEYRLRILAYCT-IYQ 306
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
D+ V + V DVND+ P+F YN V E + +V A D D G NA+ Y I
Sbjct: 307 DHTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVNASFIYEIAY 366
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ + F I +G++ VNG LDRE +D Y +TV+AR+ D ND
Sbjct: 367 AGHE--FVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFHSNVTITVMLRDEND 424
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
NSP F L + P + F V+ + + I NA + V +
Sbjct: 425 NSP---IFSRAL-YSSPIYENEPPGTF--VIQVSANDSDIGSNAMVSYAVLSDAEGHYQY 478
Query: 1207 --IGNGNGLILYSLPQRKNQQNLGLPSLSSTA-------ILMVTVADVPDEV-EMSD-KP 1255
I NG I S +R +++N+ L TA + V+V DV V +++D P
Sbjct: 479 FKINAKNGTITTS--RRLDRENITTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSP 536
Query: 1256 VFISRYYELEIEENVNAPVELVSLNLTEHYENFKMR-YYILNENDTDIRRTFVIDPRNGT 1314
F+ Y + E L ++ + ++ YI+ E ++ +F+I R+G
Sbjct: 537 EFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEG--NVEGSFIIGARSGL 594
Query: 1315 LYLVRSPDREVKDTYEVIVRA 1335
L L + DREV + + V A
Sbjct: 595 LQLNHTLDREVVSKHSLRVTA 615
Score = 104 bits (249), Expect = 2e-20
Identities = 123/477 (25%), Positives = 210/477 (44%), Gaps = 43/477 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + V L D NDN+P+F + LY + N GT + +V A D D+G N MV Y +
Sbjct: 411 SNVTITVMLRDENDNSPIFSRA-LYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL 469
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIE 558
+ FKIN GT++ + E L V ASD + R ++VV +
Sbjct: 470 SDAE-GHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIR---VSVVDVV 525
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
VT + P+F+ Y F V G +G I D + ++ Y + G E
Sbjct: 526 VT--VLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVE 583
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA-------LQENANLSIVTNATVHVVDV 669
G F + RSG++ + L R + A + + ++L+ N T++V+D
Sbjct: 584 G-SFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDS 642
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRF--LIANQQDV 726
ND V K ++ + EN+ ++GQ + H N + ++ + + + + V
Sbjct: 643 NDNIPVCDKVYYT---ISIPENT---SVGQSLIHLNCTDQDSGENAHLLYHMVSGHSKFV 696
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
D++ G + K LD E++ I + G + + V + +++ NDN P
Sbjct: 697 VDNVT----GIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPS 752
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN-----ALFMYTLFGEGKEMFDVDE 841
F Y +I E + + ++ A D D ++ YTL G F +D+
Sbjct: 753 FGQDNYTFWISEGD-FAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL-GNSTGPFAIDK 810
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDT---GGLSSEAELIIMIGDENDNKPEFNQ 895
+TGV++ +G SLDRE Y S++A+D+ L + + + + D NDN P F++
Sbjct: 811 DTGVLRAVG-SLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDR 866
Score = 100 bits (240), Expect = 3e-19
Identities = 111/413 (26%), Positives = 175/413 (42%), Gaps = 52/413 (12%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
PE P+G+T+ ++ A+D D G+N ++RY E + F IN G
Sbjct: 1080 PETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE---------------ESLFRINYTTGI 1124
Query: 1001 VIVARSLPPES--EFRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVE 1055
V + SL E+ +++L + A D G N + + + V DVND+ P F Y+ NV
Sbjct: 1125 VTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVL 1184
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E Q V V A D D NA++ Y I +TD F I+ +G + LDRET D+
Sbjct: 1185 EGQ-VGAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDR 1243
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
YILTV+A D G DVNDN P +P ++ N
Sbjct: 1244 YILTVLASDRG-EPAMNSSTNVTIHVNDVNDNKPNI--------TNNPGV-VVTRENTPP 1293
Query: 1176 VMMIPVYKAT-IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN-------- 1226
++ + A+ ++E + + D F NG I+ + QN
Sbjct: 1294 GSLVYILSASDLDEGSNARVAFSGYAVPDGKFSIKPNGEIMVRDSLDREAQNRFVFYAMA 1353
Query: 1227 --LGLPSLSSTAILM-VTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
G P +S+ + + +AD E + PVF +Y + I EN + +V +N +E
Sbjct: 1354 TDSGQPPFNSSMVSFDILIAD-----ENDNNPVFDPVHYSVNISENGPSEEVIVQVNASE 1408
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
E K+ + I + D F I G + + DRE+ +++ + AE
Sbjct: 1409 RDEG-KLLFKI---SSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAE 1457
Score = 99.5 bits (237), Expect = 6e-19
Identities = 131/467 (28%), Positives = 203/467 (43%), Gaps = 52/467 (11%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN P F ++ Y+ ++ +VG V V A+D D N ++Y + + +
Sbjct: 1166 DVNDNRPTFTHAH-YDGNVLEG-QVGAVAAIVVALDKDEEINADIVYSIIGGNT---DNS 1220
Query: 511 FKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F IN +G++ E R+ L V ASD+ P+ S VTI V NKP
Sbjct: 1221 FAINNKSGSIYTLLHLDRETTDRYILTVLASDR-GEPAMN--SSTNVTIHVN-DVNDNKP 1276
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP---FAVEER 625
+I + G N G+ V + +D E ++ GY VP F+++
Sbjct: 1277 NITNNPGVVV---TRENTPPGSLVYILSASDLDEGSNARV-AFSGY--AVPDGKFSIKP- 1329
Query: 626 SGVITVVDDLSRYNRPMYDFEAVAL---QENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+G I V D L R + + F A+A Q N S+V+ + + D ND V
Sbjct: 1330 NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVS-FDILIADENDNNPVF-----D 1383
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
P+ + V + G + I N S G + F I++ G I T+K
Sbjct: 1384 PVHYSVNISENGPSEEVIVQVNASE---RDEGKLLFKISSGDPGGYFTIHNVTGVISTRK 1440
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + +T+ AE ++G S + VTI++ DEND PV E + EN+ I
Sbjct: 1441 PLDREMVSRFDLTITAE-DEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHI 1499
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----------DENTGVVKFIGDS 852
G+ + I A D D+ +N Y++ G F++ G++ G
Sbjct: 1500 GSAVAS---INAVDKDDPSNTKITYSV---GNSAFNITTQRLPFSSGSRYRGIIITAG-L 1552
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
LDRE++ Y +++ A D G + +I+ I D NDN P FNQ N
Sbjct: 1553 LDRERQDNYNITVTASD-GNHIATCNIIVRITDVNDNSPVFNQTTMN 1598
Score = 89.4 bits (212), Expect = 7e-16
Identities = 88/332 (26%), Positives = 146/332 (43%), Gaps = 21/332 (6%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI---GP 126
I G +S + V V +++VNDN P F Y + E + A + +++
Sbjct: 726 IDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDAD 785
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS----HKPVL 182
S PL T+ F DK V G + F++ + ++P++
Sbjct: 786 SSNCPLCGKLQYTLGNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLV 845
Query: 183 LLRKV----LDYDAGDKEFQL-VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
+ V LD + D F V A+ L I A+D DL A + Y ++S
Sbjct: 846 NVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVS 905
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN F +D+V G + L +L+ + + ++ L V ++ + + A V I ++
Sbjct: 906 GNTGAAFHVDNVTGEIKLVSKLERE-----KITSYTLTVGSADGGAVPRRSTALVIIYVM 960
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
D+NDN P D + ++ENLP G V++V+ TD D+ NG Y L AF +DP
Sbjct: 961 DVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNL--TSDAFRVDPF 1018
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+G +T LDRE+ + + V A+ +N S
Sbjct: 1019 TGIITTTR--ALDRESIPAYNLMVTARNSNSS 1048
Score = 85.0 bits (201), Expect = 1e-14
Identities = 65/214 (30%), Positives = 95/214 (44%), Gaps = 23/214 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN+P G ++K+ D D NG++ Y L++DA V + G +
Sbjct: 980 ENLPAGHFVVKVVTTDPDEVHNGRVEYN-----------LTSDAFRVDPFT------GII 1022
Query: 1002 IVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
R+L ES + L ++A + + + N SV V V D NDH P F Y + E
Sbjct: 1023 TTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPET 1082
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
L +V A D D G NA + Y + ++ F I+ TG++++ LDRE + +Y
Sbjct: 1083 TPVGSTLFRVRAVDGDDGINAEVRYTLMGEES--LFRINYTTGIVTLVSSLDRENKAQYQ 1140
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L V ARD G DVNDN P F
Sbjct: 1141 LEVEARDRGIPESNANSTTILIRVGDVNDNRPTF 1174
Score = 79.8 bits (188), Expect = 5e-13
Identities = 92/366 (25%), Positives = 146/366 (39%), Gaps = 49/366 (13%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V + DVND+ PVF + Y NV E + K+ A D D NAN++Y I +T
Sbjct: 850 VTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTG 909
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F + +TG + + +L+RE Y LTV + D G DVNDNSP
Sbjct: 910 AAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGG-AVPRRSTALVIIYVMDVNDNSP- 967
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+ H+ ++V ++ EN P G V KV D D + NG
Sbjct: 968 -----------------VCLHDTQTVRLL--------ENLPAGHFVVKVVTTDPDEVHNG 1002
Query: 1211 NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
+ Y+L + + T I+ T A + + + V ++E V
Sbjct: 1003 R--VEYNLTSDAFRVD------PFTGIITTTRALDRESIPAYNLMVTARNSNSSDME--V 1052
Query: 1271 NAPVELVSLNLTEHYENFKM-RYYILNENDTDIRRTF----VIDPRNG----TLYLVRSP 1321
N V ++ ++ +H +F M RYYI T + T +D +G Y +
Sbjct: 1053 NCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE 1112
Query: 1322 DREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK---VVVRIKDVNDNSP 1378
+ + Y + RE E G+ + + +++R+ DVNDN P
Sbjct: 1113 ESLFRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRP 1172
Query: 1379 KFTNGN 1384
FT+ +
Sbjct: 1173 TFTHAH 1178
Score = 77.8 bits (183), Expect = 2e-12
Identities = 88/329 (26%), Positives = 147/329 (44%), Gaps = 42/329 (12%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG---------------EKAFIFLIAPI 124
+ V + + DVNDN+P+F Y+ TV+E G +FI+ IA
Sbjct: 308 HTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVNASFIYEIAYA 367
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
G I G+ I DR+K + + ++++ + S+ ++L
Sbjct: 368 GHEFVIG--EHSGIIIVNG--TLDREKKDLYS----ITVIARETETSAGFHSNVTITVML 419
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDR-- 241
R D + F + +S ++ F + A D D+G A + Y ++S +
Sbjct: 420 R---DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHY 476
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE---IELLD 298
+ F +++ NG++ + LD + TF L+V AS PL T + V + +LD
Sbjct: 477 QYFKINAKNGTITTSRRLDRE-----NITTFRLRVTASD-GAPLSTIRVSVVDVVVTVLD 530
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDP 356
+NDN PEF YN S++E G + + A D+D+ NG Y + + +G+F I
Sbjct: 531 INDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSFIIGA 590
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
RSG L + N T LDRE S ++V A +
Sbjct: 591 RSGLLQL-NHT-LDREVVSKHSLRVTASD 617
Score = 76.6 bits (180), Expect = 5e-12
Identities = 83/321 (25%), Positives = 139/321 (43%), Gaps = 35/321 (10%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI----GPSLTIPLTVPRG 137
SV V + D ND+ P F Y+++ E TP G +F + + G + + T+
Sbjct: 1055 SVHVIVMDTNDHTPSFTMARYYISTPETTPVGST--LFRVRAVDGDDGINAEVRYTLMGE 1112
Query: 138 LTIFKD---------IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
++F+ + + DR+ N + V D G ES+ +L +V
Sbjct: 1113 ESLFRINYTTGIVTLVSSLDRE-----NKAQYQLEVEARDRG--IPESNANSTTILIRVG 1165
Query: 189 DYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
D + F G + ++ + A+D+D + A + Y +I GN F+++
Sbjct: 1166 DVNDNRPTFTHAHY-DGNVLEGQVGAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAIN 1224
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
+ +GS++ LD + + ++L V AS P + V I + D+NDN P
Sbjct: 1225 NKSGSIYTLLHLDRET-----TDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNIT 1279
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQ 366
+ + EN P G V + A+D D+G N + P G FSI P +G + VR+
Sbjct: 1280 NNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSIKP-NGEIMVRDS 1338
Query: 367 TVLDREAHSSLRMKVYAKETN 387
LDREA + R YA T+
Sbjct: 1339 --LDREAQN--RFVFYAMATD 1355
Score = 73.7 bits (173), Expect = 3e-11
Identities = 64/225 (28%), Positives = 103/225 (45%), Gaps = 24/225 (10%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E +N + TI V N ++ + + EN P G+ + L+A DLD G N ++
Sbjct: 1255 EPAMNSSTNVTI-HVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARV 1313
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL--DGGN 1024
+ S +P K S + +G ++V SL E++ R A+ D G
Sbjct: 1314 AF---SGYAVPDGKFSI------------KPNGEIMVRDSLDREAQNRFVFYAMATDSGQ 1358
Query: 1025 LNDN---ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
N +S + + D ND+ PVF Y+ N+ E + V+ +V+A++ D G+ L
Sbjct: 1359 PPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEGK---LL 1415
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ I D F I +TGV+S LDRE ++ LT+ A D G
Sbjct: 1416 FKISSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEG 1460
Score = 72.9 bits (171), Expect = 6e-11
Identities = 54/175 (30%), Positives = 81/175 (46%), Gaps = 15/175 (8%)
Query: 218 IHAIDQDLGVGATLRYELISG-NDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVL 274
+HA D D + A + Y + N ++F++ ++ G + L LD + AE+ L+ +
Sbjct: 244 VHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEITLNGSLDRETIAEYRLRILAYCT 303
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
Q V I + D+NDN+P F + YN ++ EN G V+QV A D D
Sbjct: 304 IYQD----------HTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDID 353
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
QG N F Y++ F I SG + V LDRE + V A+ET S
Sbjct: 354 QGVNASFIYEIAYAGHEFVIGEHSGIIIVNG--TLDREKKDLYSITVIARETETS 406
Score = 66.9 bits (156), Expect = 4e-09
Identities = 43/148 (29%), Positives = 72/148 (48%), Gaps = 3/148 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQ 275
I A+D+D + + Y + GN F + + +G L L LD + ++H+L+
Sbjct: 560 ISAVDRDKDLNGNIVYIITEGNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRG 619
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ + L T V I +LD NDN+P + +Y ISI EN G S++ + TD+D
Sbjct: 620 GEFMADGSSLNTT-INVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDS 678
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTV 363
GEN Y + F +D +G +++
Sbjct: 679 GENAHLLYHMVSGHSKFVVDNVTGIMSL 706
Score = 64.9 bits (151), Expect = 2e-08
Identities = 84/325 (25%), Positives = 136/325 (41%), Gaps = 35/325 (10%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLT---VPR 136
+VT+++ DVNDN P + P V E TP G +I + + G + + + VP
Sbjct: 1263 NVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPD 1322
Query: 137 GLTIFK---DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG 193
G K +I D N V Y++ + D G SS +L + D +
Sbjct: 1323 GKFSIKPNGEIMVRDSLDREAQNRFVFYAMAT--DSGQPPFNSSMVSFDIL--IADENDN 1378
Query: 194 DKEFQLV---IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+ F V + S +E++ ++A ++D G L +++ SG+ F++ +V
Sbjct: 1379 NPVFDPVHYSVNISENGPSEEVIVQ--VNASERDEG---KLLFKISSGDPGGYFTIHNVT 1433
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + K LD + + F L + A P + A V I + D ND P E
Sbjct: 1434 GVISTRKPLDRE-----MVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCE 1488
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID----PRSGWLTVRNQ 366
+S+ EN G +V + A DKD N + TY + + AF+I P S R
Sbjct: 1489 QLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGN--SAFNITTQRLPFSSGSRYRGI 1546
Query: 367 TV----LDREAHSSLRMKVYAKETN 387
+ LDRE + + V A + N
Sbjct: 1547 IITAGLLDRERQDNYNITVTASDGN 1571
Score = 64.1 bits (149), Expect = 3e-08
Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 14/171 (8%)
Query: 991 YFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFK 1046
YF I+ G + + L E S F L I+A D G + V +FV D ND PV +
Sbjct: 1426 YFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIE 1485
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-----LPFEI-SPLTG 1100
+ +V E + + ++A D D N +TY + S + LPF S G
Sbjct: 1486 QCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRG 1545
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ G LDRE +D Y +TV A D DVNDNSP F
Sbjct: 1546 IIITAGLLDRERQDNYNITVTASDGN----HIATCNIIVRITDVNDNSPVF 1592
Score = 63.3 bits (147), Expect = 5e-08
Identities = 53/174 (30%), Positives = 86/174 (49%), Gaps = 12/174 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + + + D K FS+ NG + + LD +A+ N FV
Sbjct: 1300 LSASDLDEGSNARVAFSGYAVPDGK-FSIKP-NGEIMVRDSLDREAQ-----NRFVFYAM 1352
Query: 278 ASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P ++ +I + D NDN P F+ Y+++I EN P+ ++QV A+++D+G
Sbjct: 1353 ATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEG 1412
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK-ETNPS 389
+ F DP G F+I +G ++ R LDRE S + + A+ E PS
Sbjct: 1413 KL-LFKISSGDPGGYFTIHNVTGVISTRKP--LDREMVSRFDLTITAEDEGRPS 1463
Score = 62.1 bits (144), Expect = 1e-07
Identities = 50/175 (28%), Positives = 79/175 (45%), Gaps = 12/175 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D GV A+ YE+ F + +G + + LD + + + +
Sbjct: 347 VQAEDIDQGVNASFIYEIAYAGHE--FVIGEHSGIIIVNGTLDREKKDLYSITVIARETE 404
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
S + + + + L D NDN P F Y+ I EN P G V+QV A D D G
Sbjct: 405 TSAGFH----SNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGS 460
Query: 338 NGEFTYQ-LDDPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
N +Y L D +G F I+ ++G +T + LDRE ++ R++V A + P
Sbjct: 461 NAMVSYAVLSDAEGHYQYFKINAKNGTITTSRR--LDRENITTFRLRVTASDGAP 513
Score = 61.3 bits (142), Expect = 2e-07
Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 220 AIDQDLG-VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D + + Y ++SGN+ +F +D G + L +ELD + + N
Sbjct: 133 ATDMDAEEINQRVNYAIVSGNEDGIFDIDFNKGVIRLARELDFEQMTQYKLNISASNPLT 192
Query: 279 SQLNNPLKTAQ--ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ P V + +LD +D F Y+ SI EN G V+QV A D D+
Sbjct: 193 NDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKS 252
Query: 337 ENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N TY +D +P F+I +G +T+ LDRE + R+++ A
Sbjct: 253 INAPVTYAIDKETNPLRMFNIANITGEITLNGS--LDRETIAEYRLRILA 300
Score = 60.5 bits (140), Expect = 3e-07
Identities = 86/362 (23%), Positives = 152/362 (41%), Gaps = 39/362 (10%)
Query: 50 QNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDEL 109
+N+ FRL +G L I + + V V + D+NDN P F+ Y+ +V E
Sbjct: 497 ENITTFRLRVTASDGAPLSTIRVSV------VDVVVTVLDINDNSPEFVRPSYNFSVIET 550
Query: 110 TPTGEKAFIFLIAPIGPSLT--IPLTVPRGL---TIFKDIRAFDRDKPNTPNSDV---HY 161
G I L I + G + R+ +T + +V H
Sbjct: 551 ALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSFIIGARSGLLQLNHTLDREVVSKHS 610
Query: 162 SIVSGND-DGHFALESS--HKPVLLLRKVLDYDAG----DKEFQLVIMASGKRIHKEILF 214
V+ +D G F + S + + + VLD + DK + + + + + ++
Sbjct: 611 LRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIH 670
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++ DQD G A L Y ++SG+ + F +D+V G + L K LD + + + F +
Sbjct: 671 ---LNCTDQDSGENAHLLYHMVSGHSK--FVVDNVTGIMSLNKLLDFEEKPTV----FTV 721
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE-NLPNGFSVLQVM-ATD 332
++ P + V + + ++NDN P F D Y I E + +++ V+ A D
Sbjct: 722 AIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHD 781
Query: 333 KDQGEN-----GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
D + G+ Y L + G F+ID +G +R LDRE + V A+++
Sbjct: 782 LDADSSNCPLCGKLQYTLGNSTGPFAIDKDTG--VLRAVGSLDREGIKNYTFSVIAQDSI 839
Query: 388 PS 389
P+
Sbjct: 840 PN 841
Score = 59.7 bits (138), Expect = 6e-07
Identities = 86/359 (23%), Positives = 143/359 (39%), Gaps = 30/359 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S NV + + D NDN P + +N + N G+++ + A D D G N V +
Sbjct: 1260 SSTNVTIHVNDVNDNKP-NITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAF--- 1315
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ F I PN G + V +S E R + A+D P ++ ++V+ +
Sbjct: 1316 -SGYAVPDGKFSIKPN-GEIMVRDSLDREAQNRFVFYAMATDSGQPP----FNSSMVSFD 1369
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ + + + P F Y + N + Q+ ++ ++ + + + G + G
Sbjct: 1370 ILIADEND--NNPVFDPVHYSVNISENGPSEEVIVQVNASER-DEGKLLFKISSG-DPGG 1425
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVNDERGVLL 677
F + +GVI+ L R +D A E + T+ V D ND V+
Sbjct: 1426 YFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVI- 1484
Query: 678 KGAHSPIIFHVKEN----SAGAAIGQIFHTNMSSI-YGNGTGNVRFLIANQQDVTDDIAI 732
+ V EN SA A+I + + S+ GN F I Q+ +
Sbjct: 1485 --EQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQR-LPFSSGS 1541
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I T LDRE++D Y +TV A + + + + I D NDN PVF T
Sbjct: 1542 RYRGIIITAGLLDRERQDNYNITVTASDGNHIAT----CNIIVRITDVNDNSPVFNQTT 1596
Score = 59.3 bits (137), Expect = 8e-07
Identities = 47/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (9%)
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSE 973
G+ I V +N FA ++Q L + EN IG+ + +NA+D D N +I Y NS
Sbjct: 1468 GYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSA 1527
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNL-NDNIS 1030
I +L + RY G +I A L E + + + ++A DG ++ NI
Sbjct: 1528 FNITTQRLPFSS--GSRY------RGIIITAGLLDRERQDNYNITVTASDGNHIATCNII 1579
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEE 1056
VR + DVND+ PVF +T N ++ E
Sbjct: 1580 VR--ITDVNDNSPVFNQTTMNISLHE 1603
Score = 57.6 bits (133), Expect = 2e-06
Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F +D G + + LD ++ + L V A N+ V + ++D ND+
Sbjct: 1013 FRVDPFTGIITTTRALDRES-----IPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHT 1067
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P F + Y IS E P G ++ +V A D D G N E Y L + F I+ +G +T+
Sbjct: 1068 PSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGEESLFRINYTTGIVTL 1127
Query: 364 RNQTVLDREAHSSLRMKVYAKE 385
+ LDRE + +++V A++
Sbjct: 1128 VSS--LDRENKAQYQLEVEARD 1147
Score = 36.7 bits (81), Expect = 4.9
Identities = 17/43 (39%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
+A D D GINA++RY ++ E++ F I+ +G V +V++L R+
Sbjct: 1093 RAVDGDDGINAEVRYTLMGEES-LFRINYTTGIVTLVSSLDRE 1134
>UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3;
Danio rerio|Rep: PREDICTED: similar to Fat4 - Danio
rerio
Length = 2870
Score = 132 bits (318), Expect = 9e-29
Identities = 129/469 (27%), Positives = 214/469 (45%), Gaps = 43/469 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNP-VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+ +L S V+V + L D NDN P + PS + S NA + + + ++A D D G NG
Sbjct: 171 ETRLSSSVHVTIYLKDVNDNPPFITTPSTV---SFPENAPLQSAVTVIQATDADAGSNGE 227
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQPANPSERRYSL 552
++ + + F IN +TG V + + E + + ++ D+ P Y+L
Sbjct: 228 FVFSFESAKD----ESFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPP---LYTL 280
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
+T+ V N P+F + Y V + GT + ++ +D D+ + L
Sbjct: 281 MNLTVLVEDVNDHN----PEFTQSIYSLSVYEDAPRGTILLKVGASD----RDIGPNGLV 332
Query: 613 GYE-EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVN 670
+ F V+ G++ V++ + R P Y F A+ Q + S + V+DVN
Sbjct: 333 RFSISESGFMVDSVLGIVLVIEKMDREKTPFYSFSVFAVDQGDVQRSTTATINITVLDVN 392
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAA--IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
D + +I HV EN ++ QI H + + NG N +++
Sbjct: 393 D---CVPNFLPESLIIHVLENGEDSSQHTHQI-HASDEDLGANGQLTYSIESGNDENL-- 446
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++ +GTI + LDRE + Y + VIA + G S G + I ++D NDN PVFE
Sbjct: 447 -FSLHSNGTIQILEDLDREVKSQYVLKVIA-VDSGFPSLTGTGTLIIVVDDINDNIPVFE 504
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVK 847
+ ++E+S +GT I A+D D+GT Y+L EG + F ++ +G +
Sbjct: 505 KDIFTAHVLEDSPVGTSFLR---ITASDLDDGTIGQLRYSL--EGLDFPFFINATSGDL- 558
Query: 848 FIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEF 893
F +LDRE Y+ ++ D T LSS A +++ I D NDN P F
Sbjct: 559 FTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSF 607
Score = 112 bits (269), Expect = 8e-23
Identities = 125/472 (26%), Positives = 209/472 (44%), Gaps = 29/472 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ D +L+ V V +++ NDN PVF N + S+ ++ VG + DPD
Sbjct: 58 TAGAQHGDSELIR-VRVYFNVINVNDNPPVF-SQNAFYASIPEDSPVGMCFLSLNVSDPD 115
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSE 547
G G V +L TS + + F IN +AE ++L V+A+D A P+E
Sbjct: 116 EGIYGEV--ELAVTSG-DLENKFSINQEGTLCLIAELDRETNAMYSLIVQANDH-ALPTE 171
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS 607
R S +V VT K + D P F+ P N + ++V I+ DA ++
Sbjct: 172 TRLSSSV---HVTIYLK-DVNDNPPFITTPSTVSFPENAPLQSAVTVIQATDADAGSNGE 227
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHV 666
+ + F++ +GV+ + L R + + + L + N TV V
Sbjct: 228 FVFSFESAKDESFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLV 287
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
DVND + +S ++ E++ I + I NG VRF I+ +
Sbjct: 288 EDVNDHNPEFTQSIYSLSVY---EDAPRGTILLKVGASDRDIGPNGL--VRFSISESGFM 342
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
D + G + + +DREK Y +V A ++G + + + I + D ND P
Sbjct: 343 VDSVL----GIVLVIEKMDREKTPFYSFSVFA-VDQGDVQRSTTATINITVLDVNDCVPN 397
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGV 845
F + ++EN + ++ + I A+D D G N Y++ G + +F + N G
Sbjct: 398 FLPESLIIHVLENGEDSSQ--HTHQIHASDEDLGANGQLTYSIESGNDENLFSLHSN-GT 454
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
++ + D LDRE K Y L ++A D+G L+ LII++ D NDN P F +
Sbjct: 455 IQILED-LDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNIPVFEK 505
Score = 108 bits (259), Expect = 1e-21
Identities = 122/460 (26%), Positives = 197/460 (42%), Gaps = 32/460 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V VT+ D NDN P F+ Y ++ G+V+ V A D D+ N + +
Sbjct: 587 LSSSAAVVVTIEDVNDNFPSFLYGP-YVANIPFGLTKGSVVCTVMAEDADVELNAKLNFS 645
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
LQ F IN +TGTV +++S + V D P + +T+
Sbjct: 646 LQGQH----AHLFSINSHTGTVLISDSINRRNDITIDVHVQDGAEMP---KMDTTTLTVR 698
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ K + + + +E + IGT V + +N Y L G
Sbjct: 699 FWNDSYFPKIAVQVYKNSLFE-----DAPIGTLVAIVTAETL--KNVSVYFYLPSGNFGE 751
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVL 676
F + +G +T+ D L + MY V +++ + A +H + DVND V
Sbjct: 752 VFELHPSTGELTIKDPLD-FETNMYFHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVF 810
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + ++ EN A + + + + S G + F++ + T I G
Sbjct: 811 SQDIYKCQVY---ENLASSRVCNVLAKDADS--GVFAEVLYFILGGNIESTFKID-KNRG 864
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
T+ T K LDRE+ Y +++ A +K S + + + + D ND+ P F Y +
Sbjct: 865 TLSTTKRLDREQIPYYNLSIKA-IDKENNSLLAVASIIVEVLDTNDHAPRFTKI-YVTEV 922
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDR 855
EN+ IG + I ATD D G NA+ YT+ G E F +D+ TG + F+ LDR
Sbjct: 923 PENAPIGFSVIQ---IVATDEDAGLNAVIEYTIIGHNSEFPFSIDKTTGTL-FVSHPLDR 978
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
E + Y + + A D+ S ++ I I D NDN P F+Q
Sbjct: 979 EDQDHYIVKVNANDS-AWSISTDVTIDITDVNDNAPIFSQ 1017
Score = 107 bits (257), Expect = 2e-21
Identities = 145/612 (23%), Positives = 252/612 (41%), Gaps = 53/612 (8%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN PVF +++ + ++ VGT ++ A D D G G + Y L+ + P
Sbjct: 495 DINDNIPVF-EKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLEG-----LDFP 548
Query: 511 FKINPNTG---TVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F IN +G TVS + + L + + P P ++ VVTIE
Sbjct: 549 FFINATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAV-VVTIEDVND----- 602
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
+ P F+ PY + + G+ V + DA + + + + F++ +G
Sbjct: 603 -NFPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQGQHAHLFSINSHTG 661
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ + D ++R N D V +Q+ A + + T+ V ND I
Sbjct: 662 TVLISDSINRRNDITID---VHVQDGAEMPKMDTTTLTVRFWNDSY-------FPKIAVQ 711
Query: 688 VKENSA--GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
V +NS A IG + + N + N +V + G + + PLD
Sbjct: 712 VYKNSLFEDAPIGTLVAIVTAETLKNVSVYFYLPSGNFGEVFE--LHPSTGELTIKDPLD 769
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
E + + V A + G+ + ++ + I D NDNPPVF Y+ + EN
Sbjct: 770 FETNMYFHLIVEAR-DSGIPPFSSYAELHLNISDVNDNPPVFSQDIYKCQVYENL---AS 825
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLS 864
++ N++ A DAD G A +Y + G E F +D+N G + LDRE+ Y LS
Sbjct: 826 SRVCNVL-AKDADSGVFAEVLYFILGGNIESTFKIDKNRGTLSTT-KRLDREQIPYYNLS 883
Query: 865 LVA--RDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
+ A ++ L + A +I+ + D ND+ P F +I E N GF++I++
Sbjct: 884 IKAIDKENNSLLAVASIIVEVLDTNDHAPRFTKIYVT-------EVPENAPIGFSVIQIV 936
Query: 923 PKNKFA-----LDVDQLGPLFLIPENIPIGT-TIIKLNALDLDSGLNGQIRYEFNSEVYI 976
++ A ++ +G P +I T T+ + LD + + ++ N +
Sbjct: 937 ATDEDAGLNAVIEYTIIGHNSEFPFSIDKTTGTLFVSHPLDREDQDHYIVKVNANDSAWS 996
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK 1036
+ ++ D +V I + + + + F L +SA D +L +N V F+
Sbjct: 997 ISTDVTIDITDVNDNAPIFSQPVYSVTIPEMKMHEVFILQVSATD-RDLGENAQVLYFIN 1055
Query: 1037 DVNDHFPVFKKT 1048
N+ F V T
Sbjct: 1056 PPNELFFVNAST 1067
Score = 104 bits (250), Expect = 2e-20
Identities = 114/458 (24%), Positives = 195/458 (42%), Gaps = 26/458 (5%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V + + D NDN P+F +Y ++ I +V A D DLG+N VLY + +
Sbjct: 1000 DVTIDITDVNDNAPIF-SQPVYSVTIPEMKMHEVFILQVSATDRDLGENAQVLYFINPPN 1058
Query: 504 NLTITSPFKINPNTGTVSVAESPIL---EGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F +N +TG +S ++ L E F+ + N S S+ V +
Sbjct: 1059 EL-----FFVNASTGEISNKQTIALAELESEIFTFMVVASDCGNVSLNSSSIVSVALVQY 1113
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ P VGS V ++V Q D + N+ G + F
Sbjct: 1114 NYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQ----DYLQMNNSVEYFNSGGNGSLYF 1169
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
VE+ SG + V L+ + E A ++ L + T +V E +
Sbjct: 1170 QVEQNSGRVLVNATLANSLNMILTLEITA--KDKGLPPIAAQTEISFEVIQENQFAPQFL 1227
Query: 681 HSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+S + F V E+ G+ IG+I + + NG + F N+ + + G I
Sbjct: 1228 NSQVEFFVPEDLPVGSVIGKIQGKD-KDVGSNGVISYSFDGGNENGLFSIEHFS--GLIM 1284
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
K LD EK + + ++VIA+ + G G VT+Y+ D NDNPP+F Y ++EN
Sbjct: 1285 LVKGLDFEKSETHHLSVIAK-DGGWRPKKGRLNVTVYVTDLNDNPPIFTSKDYVASVLEN 1343
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ IGT + + A D+D G ++ Y++ ++F +D G + + + D E+
Sbjct: 1344 AFIGTLVLQ---VWAKDSDTGIHSQITYSVIAGDAQLFSLDSKNGSITTL-EIFDYEQNQ 1399
Query: 860 MYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
++L++ A + G L A + I + N+ P F +
Sbjct: 1400 HFELTVKATNIGPPFLFDIARIYIQVVGVNEFIPAFQR 1437
Score = 103 bits (248), Expect = 3e-20
Identities = 92/327 (28%), Positives = 151/327 (46%), Gaps = 23/327 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTI 130
G+ + +++TV +EDVND+ P F + Y ++V E P G + IGP+ +
Sbjct: 273 GIPPLYTLMNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLV 332
Query: 131 PLTVPRG-------LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
++ L I I DR+K TP V D + + VL
Sbjct: 333 RFSISESGFMVDSVLGIVLVIEKMDREK--TPFYSFSVFAVDQGDVQRSTTATINITVLD 390
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
+ + + + + ++ +G+ + IHA D+DLG L Y + SGND L
Sbjct: 391 VNDCVP-NFLPESLIIHVLENGEDSSQHT---HQIHASDEDLGANGQLTYSIESGNDENL 446
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FSL S NG++ + ++LD + + + +VL+V A P T + I + D+NDN+
Sbjct: 447 FSLHS-NGTIQILEDLDREVK-----SQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNI 500
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P FE D + ++E+ P G S L++ A+D D G G+ Y L+ F I+ SG L
Sbjct: 501 PVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLEGLDFPFFINATSGDLF- 559
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSV 390
+ LDRE R V + +P++
Sbjct: 560 -TVSALDRETVPFYRFLVIVSDGHPTM 585
Score = 103 bits (247), Expect = 4e-20
Identities = 119/428 (27%), Positives = 189/428 (44%), Gaps = 36/428 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +N+ V + D ND+NP F S +Y S+ +A GT++ KV A D D+G NG+V +
Sbjct: 277 LYTLMNLTVLVEDVNDHNPEFTQS-IYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFS 335
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ S F ++ G V V E ++ F S + + + S TI
Sbjct: 336 ISE-------SGFMVDSVLGIVLVIEK--MDREKTPFYSFSVFAVDQGDVQRS-TTATIN 385
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRVN--DAFEQNDVSYDLLHGY 614
+T +P+F+ V N G +S QI + D ++Y + G
Sbjct: 386 IT--VLDVNDCVPNFLPESLIIHVLEN-GEDSSQHTHQIHASDEDLGANGQLTYSIESGN 442
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV-DVNDER 673
+E + F++ +G I +++DL R + Y + +A+ T + VV D+ND
Sbjct: 443 DENL-FSLHS-NGTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNI 500
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIAI 732
V K + HV E+S +G F +S +GT G +R+ + D I
Sbjct: 501 PVFEKDIFTA---HVLEDS---PVGTSFLRITASDLDDGTIGQLRYSLEG-LDFPFFIN- 552
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G +FT LDRE YR VI + + V + IED NDN P F + Y
Sbjct: 553 ATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPY 612
Query: 793 EGFIMENSKIG-TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ N G T+ + + A DAD NA ++L G+ +F ++ +TG V I D
Sbjct: 613 ----VANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQGQHAHLFSINSHTGTV-LISD 667
Query: 852 SLDREKKI 859
S++R I
Sbjct: 668 SINRRNDI 675
Score = 96.7 bits (230), Expect = 4e-18
Identities = 129/537 (24%), Positives = 217/537 (40%), Gaps = 73/537 (13%)
Query: 873 LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTII--EVKPKNKFALD 930
++ E L ++ + + ++ I + + + ET+L+ + TI +V F
Sbjct: 137 INQEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDNPPFITT 196
Query: 931 VDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKR 990
+ PEN P+ + + + A D D+G NG+ + F S + D
Sbjct: 197 PSTVS----FPENAPLQSAVTVIQATDADAGSNGEFVFSFES---------AKD-----E 238
Query: 991 YFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFK 1046
F IN G V + + L E++ R+ + D G L +++ V V+DVNDH P F
Sbjct: 239 SFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFT 298
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
++ Y+ +V E +L KV A+D D G N + + I S F + + G++ V
Sbjct: 299 QSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSISESG----FMVDSVLGIVLVIE 354
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
++DRE Y +V A D G DVND P F + L+ +
Sbjct: 355 KMDREKTPFYSFSVFAVDQG-DVQRSTTATINITVLDVNDCVPNFLP-ESLIIHVLENGE 412
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI---GNGNGLILYSLPQRKN 1223
+ S H + ++ + + A T + ND + NG IL L +
Sbjct: 413 DSSQHTHQ------IHASDEDLGANGQLTYSIESGNDENLFSLHSNGTIQILEDLDREVK 466
Query: 1224 QQ--------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
Q + G PSL+ T L++ V D+ D + + +K +F + E + V
Sbjct: 467 SQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNIPVFEKDIFTAHVLE---DSPVGTSFL 523
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ + + ++RY + + F I+ +G L+ V + DRE Y +V
Sbjct: 524 RITASDLDDGTIGQLRYSL-----EGLDFPFFINATSGDLFTVSALDRETVPFYRFLVIV 578
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
H P++ VVV I+DVNDN P F G P V IP
Sbjct: 579 SD-------GHPTMPLSS---------SAAVVVTIEDVNDNFPSFLYG--PYVANIP 617
Score = 95.1 bits (226), Expect = 1e-17
Identities = 131/498 (26%), Positives = 208/498 (41%), Gaps = 41/498 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+NV V + D NDN P+F S Y S+ NA +GT++ +V A D D G + + Y +
Sbjct: 1315 LNVTVYVTDLNDNPPIFT-SKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAG 1373
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER-RYSLAVVTIEVTR 561
F ++ G+++ E I + E + + N + +A + I+V
Sbjct: 1374 D----AQLFSLDSKNGSITTLE--IFDYEQNQHFELTVKATNIGPPFLFDIARIYIQVV- 1426
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVP 619
G IP F Y F V + T +G I D +V Y +L G +
Sbjct: 1427 ---GVNEFIPAFQRHLYNFSVSEALMPQTEIGSILATDYDLGPDGEVFY-ILVGQSKKSN 1482
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLK 678
F V++ +G I + DL + +A A V A +H + + DE
Sbjct: 1483 FVVDKHTGKIYIAKDLKTRLKNEDVLHVLAKNRGAITGFNVDEALIH-LSILDENDPPEF 1541
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSI--YGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ I+ ++ S G +I ++ + I + + ++ N + D ++ G
Sbjct: 1542 DSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWSRFSYSIEHGNINSSFIIDPVS----G 1597
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I LDRE +Y +TVIA ++G S G +V I + D ND+PP + T EGFI
Sbjct: 1598 VISVNSHLDREIWAIYNLTVIA-VDEGSPSVTGSTKVAITVNDINDSPP--KLLTTEGFI 1654
Query: 797 MENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
EN T + + + ATD D N F Y + E F + T V DR
Sbjct: 1655 RENQPADTLV---STLTATDDDLPPNQGPFTYWMM-RPAEGFSL--TTEGVLVTSKPFDR 1708
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
E ++ + +V +D G +SS I + DENDN P I N V+ + + G
Sbjct: 1709 EHDPLFHMHIVVQDAGKPPMSSTTLFHIKVLDENDNAPVPRNI--NILVKYYGSSFPGGL 1766
Query: 914 AGFTIIEVKPKNKFALDV 931
G V+P + LDV
Sbjct: 1767 IG----NVRPTDLDELDV 1780
Score = 90.6 bits (215), Expect = 3e-16
Identities = 104/425 (24%), Positives = 182/425 (42%), Gaps = 37/425 (8%)
Query: 477 TVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFV 536
T++G V+AV + +N +Y +Q + F +NP++G ++ + E +
Sbjct: 3 TIVGHVEAVYSE--KNKTSVYSVQEDDGDGL---FLLNPHSGEFLLSRALDFEIERYYIL 57
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
A Q + R + I V + P P F + + + +G +
Sbjct: 58 TAGAQHGDSELIRVRVYFNVINVN-----DNP--PVFSQNAFYASIPEDSPVGMCFLSLN 110
Query: 597 VNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA----L 650
V+D E +V + G E F++ + G + ++ +L R MY A L
Sbjct: 111 VSDPDEGIYGEVELAVTSGDLEN-KFSINQE-GTLCLIAELDRETNAMYSLIVQANDHAL 168
Query: 651 QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG 710
LS + T+++ DVND + +P EN+ + + +
Sbjct: 169 PTETRLSSSVHVTIYLKDVNDNPPFIT----TPSTVSFPENAPLQSAVTVIQATDADAGS 224
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
NG F A + + + + G ++ QKPLDRE +DV R+ + + +KG+ +
Sbjct: 225 NGEFVFSFESAKDESFSIN---SSTGVVYLQKPLDRETKDVIRVMLKVK-DKGIPPLYTL 280
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+T+ +ED ND+ P F + Y + E++ GT + + A+D D G N L +++
Sbjct: 281 MNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTILLK---VGASDRDIGPNGLVRFSIS 337
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDEND 888
G F VD G+V I + +DREK Y S+ A D G + S+ A + I + D ND
Sbjct: 338 ESG---FMVDSVLGIVLVI-EKMDREKTPFYSFSVFAVDQGDVQRSTTATINITVLDVND 393
Query: 889 NKPEF 893
P F
Sbjct: 394 CVPNF 398
Score = 87.8 bits (208), Expect = 2e-15
Identities = 116/474 (24%), Positives = 199/474 (41%), Gaps = 63/474 (13%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ P+GT+ +++ A DLD G GQ+RY S + L+ F IN G +
Sbjct: 514 EDSPVGTSFLRITASDLDDGTIGQLRY-------------SLEGLDFP--FFINATSGDL 558
Query: 1002 IVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+L E+ +R + DG L+ + +V V ++DVND+FP F Y N+
Sbjct: 559 FTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPYVANIPF 618
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
V+ V A DAD NA L + +Q L F I+ TG + ++ ++R +
Sbjct: 619 GLTKGSVVCTVMAEDADVELNAKLNFSLQGQHAHL-FSINSHTGTVLISDSINRRND--I 675
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
+ V +D D + L P ++ E++
Sbjct: 676 TIDVHVQDGAEMPKMDTTTLTVRFWNDSYFPKIAVQVYKNSLFEDAPIGTLVAIVTAETL 735
Query: 1177 MMIPVY----KATIEENAPIGTTVAKVFAND-TDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
+ VY E + + ++ D DF N + + + + ++ G+P
Sbjct: 736 KNVSVYFYLPSGNFGEVFELHPSTGELTIKDPLDFETN---MYFHLIVEARDS---GIPP 789
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV-NAPVELVSLNLTEHYENFKM 1290
SS A L + ++DV D + PVF Y+ ++ EN+ ++ V V + ++
Sbjct: 790 FSSYAELHLNISDVND-----NPPVFSQDIYKCQVYENLASSRVCNVLAKDADSGVFAEV 844
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y+IL N I TF ID GTL + DRE Y + ++A ++ + +
Sbjct: 845 LYFILGGN---IESTFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKE-----NNSLLA 896
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
VA ++V + D ND++P+FT + VT +P AP G+ V+Q+
Sbjct: 897 VA------------SIIVEVLDTNDHAPRFT---KIYVTEVPENAPIGFSVIQI 935
Score = 86.2 bits (204), Expect = 6e-15
Identities = 87/355 (24%), Positives = 154/355 (43%), Gaps = 29/355 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + ++ N+ P F +LY FS+ T IG + A D DLG +G V Y
Sbjct: 1415 LFDIARIYIQVVGVNEFIPAF-QRHLYNFSVSEALMPQTEIGSILATDYDLGPDGEVFYI 1473
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVT 556
L S S F ++ +TG + +A+ L+ L V A ++ A + A++
Sbjct: 1474 LVGQSK---KSNFVVDKHTGKIYIAKDLKTRLKNEDVLHVLAKNRGA-ITGFNVDEALIH 1529
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHG 613
+ + ++ D P+F Y V ++ IGTS+ +++ D E + SY + HG
Sbjct: 1530 LSIL-----DENDPPEFDSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWSRFSYSIEHG 1584
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDE 672
F ++ SGVI+V L R +Y+ +A+ E + +++ T + V D+ND
Sbjct: 1585 -NINSSFIIDPVSGVISVNSHLDREIWAIYNLTVIAVDEGSPSVTGSTKVAITVNDINDS 1643
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
LL ++EN + + N G + + + ++
Sbjct: 1644 PPKLLTTEG-----FIRENQPADTLVSTLTATDDDLPPN-QGPFTYWMMRP---AEGFSL 1694
Query: 733 AEDGTIFTQKPLDREKRDVYRM-TVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+G + T KP DRE ++ M V+ + K +S ++ + + DENDN PV
Sbjct: 1695 TTEGVLVTSKPFDREHDPLFHMHIVVQDAGKPPMSSTTLFHIKVL--DENDNAPV 1747
Score = 85.8 bits (203), Expect = 8e-15
Identities = 116/475 (24%), Positives = 203/475 (42%), Gaps = 44/475 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ D Q + + +T+LD ND P F+P +L +++ ++ A D DLG
Sbjct: 371 VDQGDVQRSTTATINITVLDVNDCVPNFLPESLIIHVLENGEDSSQHTHQIHASDEDLGA 430
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERR 549
NG + Y ++ ++ + F ++ N GT+ + E ++ ++ L V A D
Sbjct: 431 NGQLTYSIESGNDENL---FSLHSN-GTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGT 486
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
+L +V ++ +IP F + V + +GTS +I +D +D +
Sbjct: 487 GTLIIVVDDI-------NDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDL---DDGTIG 536
Query: 610 LLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
L EG+ PF + SG + V L R P Y F + + + + ++A V V
Sbjct: 537 QLRYSLEGLDFPFFINATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVT 596
Query: 668 --DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQ 724
DVND L G P + ++ G G + T M+ + F + Q
Sbjct: 597 IEDVNDNFPSFLYG---PYVANI---PFGLTKGSVVCTVMAEDADVELNAKLNFSLQGQH 650
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
I + GT+ ++R + D+ T+ G + T+ + ND+
Sbjct: 651 AHLFSIN-SHTGTVLISDSINR-RNDI---TIDVHVQDGA-EMPKMDTTTLTVRFWNDSY 704
Query: 785 -PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDEN 842
P Y+ + E++ IGT ++ A+ N +++ Y G E+F++ +
Sbjct: 705 FPKIAVQVYKNSLFEDAPIGT------LVAIVTAETLKNVSVYFYLPSGNFGEVFELHPS 758
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
TG + I D LD E + + L + ARD+G SS AEL + I D NDN P F+Q
Sbjct: 759 TGELT-IKDPLDFETNMYFHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQ 812
Score = 85.8 bits (203), Expect = 8e-15
Identities = 61/173 (35%), Positives = 88/173 (50%), Gaps = 10/173 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D GV A + Y ++ GN F +D G+L K LD + Q + L ++A
Sbjct: 833 AKDADSGVFAEVLYFILGGNIESTFKIDKNRGTLSTTKRLDRE-----QIPYYNLSIKAI 887
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
N A A + +E+LD ND+ P F Y + EN P GFSV+Q++ATD+D G N
Sbjct: 888 DKENNSLLAVASIIVEVLDTNDHAPRF-TKIYVTEVPENAPIGFSVIQIVATDEDAGLNA 946
Query: 340 --EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
E+T + + FSID +G L V + LDRE +KV A ++ S+
Sbjct: 947 VIEYTIIGHNSEFPFSIDKTTGTLFVSHP--LDREDQDHYIVKVNANDSAWSI 997
Score = 85.0 bits (201), Expect = 1e-14
Identities = 74/318 (23%), Positives = 137/318 (43%), Gaps = 29/318 (9%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF------------ 119
+G+ S+Y + + I DVNDN P+F Y V E + +
Sbjct: 785 SGIPPFSSYAELHLNISDVNDNPPVFSQDIYKCQVYENLASSRVCNVLAKDADSGVFAEV 844
Query: 120 LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
L +G ++ + + + DR++ P ++ + ++ A+ S
Sbjct: 845 LYFILGGNIESTFKIDKNRGTLSTTKRLDREQ--IPYYNLSIKAIDKENNSLLAVAS--- 899
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
++ +VLD + F + + I A D+D G+ A + Y +I N
Sbjct: 900 ---IIVEVLDTNDHAPRFTKIYVTEVPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGHN 956
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
FS+D G+LF+ LD + + + ++++V A N+ + V I++ D+
Sbjct: 957 SEFPFSIDKTTGTLFVSHPLDREDQDH-----YIVKVNA---NDSAWSISTDVTIDITDV 1008
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
NDN P F Y+++I E + +LQV ATD+D GEN + Y ++ P F ++ +G
Sbjct: 1009 NDNAPIFSQPVYSVTIPEMKMHEVFILQVSATDRDLGENAQVLYFINPPNELFFVNASTG 1068
Query: 360 WLTVRNQTVLDREAHSSL 377
++ QT+ E S +
Sbjct: 1069 EIS-NKQTIALAELESEI 1085
Score = 77.0 bits (181), Expect = 4e-12
Identities = 92/357 (25%), Positives = 152/357 (42%), Gaps = 35/357 (9%)
Query: 58 GCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G DF++ + ++ G L+VTVY+ D+NDN PIF Y +V E G
Sbjct: 1288 GLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFTSKDYVASVLENAFIG 1347
Query: 114 EKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFA 173
+ +T I D + F D N + + N
Sbjct: 1348 TLVLQVWAKDSDTGIHSQITYS---VIAGDAQLFSLDSKNGSITTLEIFDYEQNQHFELT 1404
Query: 174 LESSH--KPVLL-LRKVLDYDAGDKEFQLVIMASGKRIHK----EILFPEP----IHAID 222
+++++ P L + ++ G EF I A + ++ E L P+ I A D
Sbjct: 1405 VKATNIGPPFLFDIARIYIQVVGVNEF---IPAFQRHLYNFSVSEALMPQTEIGSILATD 1461
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
DLG + Y L+ + + F +D G +++ K+L + N VL V A
Sbjct: 1462 YDLGPDGEVFYILVGQSKKSNFVVDKHTGKIYIAKDLKTRLK-----NEDVLHVLAKNRG 1516
Query: 283 --NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ-GENG 339
+A + + +LD ND PEF+ Y +++ E++ G S+ +V A D D E
Sbjct: 1517 AITGFNVDEALIHLSILDENDP-PEFDSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWS 1575
Query: 340 EFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-KETNPSVVGT 393
F+Y ++ + +F IDP SG ++V + LDRE + + V A E +PSV G+
Sbjct: 1576 RFSYSIEHGNINSSFIIDPVSGVISVNSH--LDREIWAIYNLTVIAVDEGSPSVTGS 1630
Score = 76.6 bits (180), Expect = 5e-12
Identities = 82/303 (27%), Positives = 130/303 (42%), Gaps = 43/303 (14%)
Query: 120 LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
+ P P ++IPLT+ G + + + A D+D NS V Y GN +F +E +
Sbjct: 1119 MFLPFKPLVSIPLTLDVGSEVIQ-VSAVDQDYLQMNNS-VEYFNSGGNGSLYFQVEQNSG 1176
Query: 180 PVLL-------LRKVLDYDAGDKEFQLVIMASGKRIHKEIL-----------------FP 215
VL+ L +L + K+ L +A+ I E++ P
Sbjct: 1177 RVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEVIQENQFAPQFLNSQVEFFVP 1236
Query: 216 E--PIHAI-------DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
E P+ ++ D+D+G + Y GN+ LFS++ +G + L K LD +
Sbjct: 1237 EDLPVGSVIGKIQGKDKDVGSNGVISYSFDGGNENGLFSIEHFSGLIMLVKGLDFE---- 1292
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
++ T L V A K + V + + DLNDN P F Y S++EN G VL
Sbjct: 1293 -KSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFTSKDYVASVLENAFIGTLVL 1351
Query: 327 QVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
QV A D D G + + TY + FS+D ++G +T + D E + + V A
Sbjct: 1352 QVWAKDSDTGIHSQITYSVIAGDAQLFSLDSKNGSITTLE--IFDYEQNQHFELTVKATN 1409
Query: 386 TNP 388
P
Sbjct: 1410 IGP 1412
Score = 75.8 bits (178), Expect = 9e-12
Identities = 57/168 (33%), Positives = 80/168 (47%), Gaps = 9/168 (5%)
Query: 988 VKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFP 1043
++ F I++ G + + L E + L+I A+D N L S+ V V D NDH P
Sbjct: 853 IESTFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKENNSLLAVASIIVEVLDTNDHAP 912
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F K + E A V+ ++ ATD D G NA + Y I +++ PF I TG L
Sbjct: 913 RFTKIYVTEVPENAPIGFSVI-QIVATDEDAGLNAVIEYTIIGHNSEFPFSIDKTTGTLF 971
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V+ LDRE +D YI+ V A D+ DVNDN+P F
Sbjct: 972 VSHPLDREDQDHYIVKVNANDS----AWSISTDVTIDITDVNDNAPIF 1015
Score = 74.9 bits (176), Expect = 2e-11
Identities = 98/468 (20%), Positives = 195/468 (41%), Gaps = 29/468 (6%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
I+ + L++ ++ V +LD ND+ P F + +Y + NA +G + ++ A D D G
Sbjct: 887 IDKENNSLLAVASIIVEVLDTNDHAPRF--TKIYVTEVPENAPIGFSVIQIVATDEDAGL 944
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS 551
N ++ Y + ++ PF I+ TGT+ V+ E + V+ N ++ +S
Sbjct: 945 NAVIEYTIIGHNS---EFPFSIDKTTGTLFVSHPLDREDQDHYIVK-----VNANDSAWS 996
Query: 552 LAV-VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
++ VTI++T + P F Y + + Q+ D + + + L
Sbjct: 997 ISTDVTIDIT----DVNDNAPIFSQPVYSVTIPEMKMHEVFILQVSATDR-DLGENAQVL 1051
Query: 611 LHGYEEGVPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
F V +G I+ L+ ++ F VA + N+S+ +++ V V
Sbjct: 1052 YFINPPNELFFVNASTGEISNKQTIALAELESEIFTFMVVA-SDCGNVSLNSSSIVSVAL 1110
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
V + P++ G+ + Q+ + + N +V + +
Sbjct: 1111 VQYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQDYLQMN--NSVEYFNSGGNGSLY 1168
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G + L + + + A+ +KG+ A +++ + EN P F
Sbjct: 1169 FQVEQNSGRVLVNATLANSLNMILTLEITAK-DKGLPPIAAQTEISFEVIQENQFAPQFL 1227
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVK 847
++ E F+ E+ +G+ I I+ D D G+N + Y+ G + +F ++ +G++
Sbjct: 1228 NSQVEFFVPEDLPVGSVI---GKIQGKDKDVGSNGVISYSFDGGNENGLFSIEHFSGLIM 1284
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAEL--IIMIGDENDNKPEF 893
+ LD EK + LS++A+D G + L + + D NDN P F
Sbjct: 1285 LV-KGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIF 1331
Score = 74.9 bits (176), Expect = 2e-11
Identities = 114/493 (23%), Positives = 194/493 (39%), Gaps = 60/493 (12%)
Query: 920 EVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
EV +N+FA F +PE++P+G+ I K+ D D G NG I Y F
Sbjct: 1215 EVIQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSF--------- 1265
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFV 1035
D F I G +++ + L E L++ A DGG ++V V+V
Sbjct: 1266 ----DGGNENGLFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYV 1321
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D+ND+ P+F Y +V E + ++ +V A D+D G ++ +TY + D L F +
Sbjct: 1322 TDLNDNPPIFTSKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAGDAQL-FSL 1380
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
G ++ D E + LTV A + G VN+ P F
Sbjct: 1381 DSKNGSITTLEIFDYEQNQHFELTVKATNIG-PPFLFDIARIYIQVVGVNEFIPAFQR-- 1437
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTT--VAKVFANDTDFI---GNG 1210
L + EA + S++ AT + P G + + ++F+ G
Sbjct: 1438 HLYNFSVSEA-LMPQTEIGSIL------ATDYDLGPDGEVFYILVGQSKKSNFVVDKHTG 1490
Query: 1211 NGLILYSLPQR-KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK---PVFISRYYELEI 1266
I L R KN+ L + + + AI V + + + D+ P F S Y + +
Sbjct: 1491 KIYIAKDLKTRLKNEDVLHVLAKNRGAITGFNVDEALIHLSILDENDPPEFDSMLYIVAV 1550
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
E+++ + + + + + + +I +F+IDP +G + + DRE+
Sbjct: 1551 SEDISIGTSIAKVKAVDPDVILEWSRFSYSIEHGNINSSFIIDPVSGVISVNSHLDREIW 1610
Query: 1327 DTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK------F 1380
Y + V +A D KV + + D+ND+ PK F
Sbjct: 1611 AIYNLTV-----------------IAVDEGSPSVTGSTKVAITVNDINDSPPKLLTTEGF 1653
Query: 1381 TNGNRPLVTAIPT 1393
N+P T + T
Sbjct: 1654 IRENQPADTLVST 1666
Score = 73.3 bits (172), Expect = 5e-11
Identities = 79/288 (27%), Positives = 130/288 (45%), Gaps = 52/288 (18%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ P+G + LN D D G+ G++ +L+ + +++ F IN+ G
Sbjct: 96 IPEDSPVGMCFLSLNVSDPDEGIYGEV-------------ELAVTSGDLENKFSINQE-G 141
Query: 1000 HVIVARSLPPESE--FRLNISALDGG-----NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ + L E+ + L + A D L+ ++ V +++KDVND+ P F T
Sbjct: 142 TLCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDN-PPFITTPSTV 200
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E + + + ATDAD G N + + S D F I+ TGV+ + LDRET
Sbjct: 201 SFPENAPLQSAVTVIQATDADAGSNGEFVFSFE-SAKDESFSINSSTGVVYLQKPLDRET 259
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+D + + +D G DVND++P+F
Sbjct: 260 KDVIRVMLKVKDKG-IPPLYTLMNLTVLVEDVNDHNPEF--------------------- 297
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
+S+ + VY E+AP GT + KV A+D D IG NGL+ +S+ +
Sbjct: 298 TQSIYSLSVY-----EDAPRGTILLKVGASDRD-IG-PNGLVRFSISE 338
Score = 72.5 bits (170), Expect = 8e-11
Identities = 82/338 (24%), Positives = 142/338 (42%), Gaps = 26/338 (7%)
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI 121
D+ +V++ A + S VT+ I DVNDN PIF Y VT+ E+ + FI +
Sbjct: 980 DQDHYIVKVNANDSAWSISTDVTIDITDVNDNAPIFSQPVYSVTIPEMKM--HEVFILQV 1037
Query: 122 A----PIGPSLTIPLTV-PRGLTIFKDIRAFDRDKPNT-----PNSDVHYSIVSGNDDGH 171
+ +G + + + P F + + T S++ +V +D G+
Sbjct: 1038 SATDRDLGENAQVLYFINPPNELFFVNASTGEISNKQTIALAELESEIFTFMVVASDCGN 1097
Query: 172 FALESSHKPVLLLRKVLDYDAGDKEFQ-LVIMASGKRIHKEILFPEPIHAIDQD-LGVGA 229
+L SS + L + + F+ LV + + E++ + A+DQD L +
Sbjct: 1098 VSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSEVI---QVSAVDQDYLQMNN 1154
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
++ Y GN F ++ +G + + L N L++ A P AQ
Sbjct: 1155 SVEYFNSGGNGSLYFQVEQNSGRVLVNATL-----ANSLNMILTLEITAKDKGLPPIAAQ 1209
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--D 347
+ E++ N P+F + E+LP G + ++ DKD G NG +Y D +
Sbjct: 1210 TEISFEVIQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDGGN 1269
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G FSI+ SG + + LD E + + V AK+
Sbjct: 1270 ENGLFSIEHFSGLIMLVKG--LDFEKSETHHLSVIAKD 1305
Score = 69.7 bits (163), Expect = 6e-10
Identities = 79/329 (24%), Positives = 143/329 (43%), Gaps = 26/329 (7%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPS----LT 129
++S+ + VT+Y++DVNDN P F+ TP V+ E P + A G + +
Sbjct: 173 RLSSSVHVTIYLKDVNDNPP-FITTPSTVSFPENAPLQSAVTVIQATDADAGSNGEFVFS 231
Query: 130 IPLTVPRGLTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+I KP + DV ++ D G L + +L+ V
Sbjct: 232 FESAKDESFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVN 291
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
D++ + + IL + A D+D+G +R+ + F +DS
Sbjct: 292 DHNPEFTQSIYSLSVYEDAPRGTILLK--VGASDRDIGPNGLVRFSISESG----FMVDS 345
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
V G + + +++D + + + V A + ++ A + I +LD+ND +P F
Sbjct: 346 VLGIVLVIEKMDRE-----KTPFYSFSVFAVDQGDVQRSTTATINITVLDVNDCVPNFLP 400
Query: 309 DFYNISIVENLPNGFS-VLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRN 365
+ I ++EN + Q+ A+D+D G NG+ TY ++ + + FS+ T++
Sbjct: 401 ESLIIHVLENGEDSSQHTHQIHASDEDLGANGQLTYSIESGNDENLFSLHSNG---TIQI 457
Query: 366 QTVLDREAHSSLRMKVYAKETN-PSVVGT 393
LDRE S +KV A ++ PS+ GT
Sbjct: 458 LEDLDREVKSQYVLKVIAVDSGFPSLTGT 486
Score = 69.3 bits (162), Expect = 8e-10
Identities = 57/191 (29%), Positives = 93/191 (48%), Gaps = 20/191 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN PIG ++I++ A D D+GLN I Y P F I++ G
Sbjct: 922 VPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGHNSEFP-------------FSIDKTTG 968
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V+ L E + + + ++A D + + V + + DVND+ P+F + Y+ + E
Sbjct: 969 TLFVSHPLDREDQDHYIVKVNANDSA-WSISTDVTIDITDVNDNAPIFSQPVYSVTIPEM 1027
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ + +V ATD D G+NA + YFI P + +L F ++ TG +S + + I
Sbjct: 1028 KMHEVFILQVSATDRDLGENAQVLYFINPPN-EL-FFVNASTGEISNKQTIALAELESEI 1085
Query: 1118 LT--VVARDNG 1126
T VVA D G
Sbjct: 1086 FTFMVVASDCG 1096
Score = 68.1 bits (159), Expect = 2e-09
Identities = 90/374 (24%), Positives = 150/374 (40%), Gaps = 29/374 (7%)
Query: 24 YRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSV 83
Y + N+T V + D L + DF+ + + S + V
Sbjct: 12 YSEKNKTSVYSVQEDDGDGLFLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDSELIRV 71
Query: 84 TVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
VY +VNDN P+F ++ ++ E +P G F+ L P I V +T
Sbjct: 72 RVYFNVINVNDNPPVFSQNAFYASIPEDSPVG-MCFLSLNVS-DPDEGIYGEVELAVTSG 129
Query: 142 KDIRAFDRDKPNT--------PNSDVHYS-IVSGNDDG---HFALESSHKPVLLLRKVLD 189
F ++ T ++ YS IV ND L SS + L+ V D
Sbjct: 130 DLENKFSINQEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVND 189
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
V + + I A D D G + S D FS++S
Sbjct: 190 NPPFITTPSTVSFPENAPLQSAVTV---IQATDADAGSNGEFVFSFESAKDES-FSINSS 245
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G ++L+K LD + + ++ +L+V+ + PL T + + + D+ND+ PEF
Sbjct: 246 TGVVYLQKPLDRETKDVIRV---MLKVKDKGIP-PLYTLM-NLTVLVEDVNDHNPEFTQS 300
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVL 369
Y++S+ E+ P G +L+V A+D+D G NG + + + F +D G + V + +
Sbjct: 301 IYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSISE--SGFMVDSVLGIVLVIEK--M 356
Query: 370 DREAHSSLRMKVYA 383
DRE V+A
Sbjct: 357 DREKTPFYSFSVFA 370
Score = 67.7 bits (158), Expect = 2e-09
Identities = 94/411 (22%), Positives = 164/411 (39%), Gaps = 50/411 (12%)
Query: 936 PLFLIPENIPIGTTIIKLNALDLDS-GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
PL IP + +G+ +I+++A+D D +N + Y FNS +L YF +
Sbjct: 1125 PLVSIPLTLDVGSEVIQVSAVDQDYLQMNNSVEY-FNSG--------GNGSL----YFQV 1171
Query: 995 NERHGHVIVARSLPPESEF--RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWY 1050
+ G V+V +L L I+A D G + + V N P F +
Sbjct: 1172 EQNSGRVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEVIQENQFAPQFLNSQV 1231
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F V E V+GK+ D D G N ++Y + + F I +G++ + LD
Sbjct: 1232 EFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDGGNENGLFSIEHFSGLIMLVKGLDF 1291
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E + + L+V+A+D G D+NDN P F + D + A L N
Sbjct: 1292 EKSETHHLSVIAKDGG-WRPKKGRLNVTVYVTDLNDNPPIFTSKDYV-------ASVLEN 1343
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG----NGNGLILYSLPQRKNQQ- 1225
F +++ V+ + T + V A D NG+ L +NQ
Sbjct: 1344 -AFIGTLVLQVWAKDSDTGIHSQITYS-VIAGDAQLFSLDSKNGSITTLEIFDYEQNQHF 1401
Query: 1226 -------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
N+G P L A + + V V + + P F Y + E + E+ S
Sbjct: 1402 ELTVKATNIGPPFLFDIARIYIQVVGVNEFI-----PAFQRHLYNFSVSEALMPQTEIGS 1456
Query: 1279 LNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
+ T++ + ++ Y ++ ++ + FV+D G +Y+ + +K+
Sbjct: 1457 ILATDYDLGPDGEVFYILVGQSK---KSNFVVDKHTGKIYIAKDLKTRLKN 1504
Score = 66.9 bits (156), Expect = 4e-09
Identities = 57/172 (33%), Positives = 83/172 (48%), Gaps = 13/172 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++ D D G+ + + SG+ FS++ G+L L ELD E N + L VQ
Sbjct: 109 LNVSDPDEGIYGEVELAVTSGDLENKFSINQ-EGTLCLIAELD--RETNAM---YSLIVQ 162
Query: 278 ASQLNNPLKT---AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A+ P +T + V I L D+NDN P F +S EN P +V + ATD D
Sbjct: 163 ANDHALPTETRLSSSVHVTIYLKDVNDN-PPFITTPSTVSFPENAPLQSAVTVIQATDAD 221
Query: 335 QGENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NGEF + + K +FSI+ +G V Q LDRE +R+ + K+
Sbjct: 222 AGSNGEFVFSFESAKDESFSINSSTG--VVYLQKPLDRETKDVIRVMLKVKD 271
Score = 66.9 bits (156), Expect = 4e-09
Identities = 80/321 (24%), Positives = 131/321 (40%), Gaps = 25/321 (7%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S+ +V V IEDVNDN P FL PY + P G + + + L
Sbjct: 587 LSSSAAVVVTIEDVNDNFPSFLYGPYVANI----PFGLTKGSVVCTVMAEDADVELNAKL 642
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGND---DGHFALESSHKPVLLLRKVLDYDAG 193
++ +T + SI ND D H + + P + +
Sbjct: 643 NFSLQGQHAHLFSINSHTGTVLISDSINRRNDITIDVHVQ-DGAEMPKMDTTTLTVRFWN 701
Query: 194 DKEFQLVIMASGKRIHKEILFPE-PIHA----IDQDLGVGATLRYELISGNDRKLFSLDS 248
D F + + +++K LF + PI + + ++ + L SGN ++F L
Sbjct: 702 DSYFPKIAV----QVYKNSLFEDAPIGTLVAIVTAETLKNVSVYFYLPSGNFGEVFELHP 757
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
G L ++ LD E N+ F L V+A P ++ A + + + D+NDN P F
Sbjct: 758 STGELTIKDPLDF--ETNMY---FHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQ 812
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
D Y + ENL + V V+A D D G E Y + + + F ID G L+ +
Sbjct: 813 DIYKCQVYENLASS-RVCNVLAKDADSGVFAEVLYFILGGNIESTFKIDKNRGTLSTTKR 871
Query: 367 TVLDREAHSSLRMKVYAKETN 387
++ + +L +K KE N
Sbjct: 872 LDREQIPYYNLSIKAIDKENN 892
Score = 64.5 bits (150), Expect = 2e-08
Identities = 75/293 (25%), Positives = 120/293 (40%), Gaps = 15/293 (5%)
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
F L + A D G + + + + DVND+ PVF + Y V E + RV V A
Sbjct: 776 FHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQDIYKCQVYENLASSRVCN-VLAK 834
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
DAD G A + YFI + + F+I G LS LDRE Y L++ A D
Sbjct: 835 DADSGVFAEVLYFILGGNIESTFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDK-ENNS 893
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
D ND++P+ F ++ + PE + SV+ I NA
Sbjct: 894 LLAVASIIVEVLDTNDHAPR---FTKIYVTEVPENAPIG----FSVIQIVATDEDAGLNA 946
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVP-DEV 1249
I T+ + I G + S P + Q+ + +++ DV D
Sbjct: 947 VIEYTIIGHNSEFPFSIDKTTGTLFVSHPLDREDQDHYIVKVNANDSAWSISTDVTIDIT 1006
Query: 1250 EMSDK-PVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNEND 1299
+++D P+F Y + I E V ++ ++ T+ EN ++ Y+I N+
Sbjct: 1007 DVNDNAPIFSQPVYSVTIPEMKMHEVFILQVSATDRDLGENAQVLYFINPPNE 1059
Score = 64.1 bits (149), Expect = 3e-08
Identities = 81/357 (22%), Positives = 145/357 (40%), Gaps = 21/357 (5%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVND-HFPVFKKTWY 1050
F IN G V+++ S+ ++ +++ DG + + + V+ ND +FP Y
Sbjct: 654 FSINSHTGTVLISDSINRRNDITIDVHVQDGAEMPKMDTTTLTVRFWNDSYFPKIAVQVY 713
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
++ E ++ V A +N ++ +++ + FE+ P TG L++ LD
Sbjct: 714 KNSLFEDAPIGTLVAIVTAETL---KNVSVYFYLPSGNFGEVFELHPSTGELTIKDPLDF 770
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
ET + L V ARD+G DVNDN P F ++ +K + L++
Sbjct: 771 ETNMYFHLIVEARDSG-IPPFSSYAELHLNISDVNDNPPVF--SQDI--YKCQVYENLAS 825
Query: 1171 HNFESVMMIPVYKATIEE--NAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK-NQQNL 1227
+V+ E +G + F D + G L + + NL
Sbjct: 826 SRVCNVLAKDADSGVFAEVLYFILGGNIESTFKIDKN---RGTLSTTKRLDREQIPYYNL 882
Query: 1228 GLPSLSSTAILMVTVADVPDEV-EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
+ ++ ++ VA + EV + +D ++ Y E+ EN ++ + T+
Sbjct: 883 SIKAIDKENNSLLAVASIIVEVLDTNDHAPRFTKIYVTEVPENAPIGFSVIQIVATDEDA 942
Query: 1287 --NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
N + Y I+ N F ID GTL++ DRE +D Y V V A +S
Sbjct: 943 GLNAVIEYTIIGHNS---EFPFSIDKTTGTLFVSHPLDREDQDHYIVKVNANDSAWS 996
Score = 57.2 bits (132), Expect = 3e-06
Identities = 88/365 (24%), Positives = 142/365 (38%), Gaps = 41/365 (11%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF--VKDVNDHFPVFKKTW 1049
F++N G +++R+L E E ++A ++ I VRV+ V +VND+ PVF +
Sbjct: 32 FLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDSELIRVRVYFNVINVNDNPPVFSQNA 91
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ ++ E ++ +D D G + + D + F I+ G L + ELD
Sbjct: 92 FYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELAVTSGDLENKFSINQ-EGTLCLIAELD 150
Query: 1110 RETEDKYILTVVARDNG--XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
RET Y L V A D+ DVNDN P F + + PE
Sbjct: 151 RETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDN-PPFITTPSTVSF--PENAP 207
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKV-FANDTDF-IGNGNGLILYSLPQRKNQQ 1225
L + + V +AT + G V A D F I + G++ P + +
Sbjct: 208 LQS-------AVTVIQATDADAGSNGEFVFSFESAKDESFSINSSTGVVYLQKPLDRETK 260
Query: 1226 NL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
++ G+P L + L V V DV D P F Y L + E+
Sbjct: 261 DVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDH-----NPEFTQSIYSLSVYEDAPRGTI 315
Query: 1276 LVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
L+ + ++ N +R+ I F++D G + ++ DRE Y V
Sbjct: 316 LLKVGASDRDIGPNGLVRFSISESG-------FMVDSVLGIVLVIEKMDREKTPFYSFSV 368
Query: 1334 RAERQ 1338
A Q
Sbjct: 369 FAVDQ 373
Score = 49.6 bits (113), Expect = 6e-04
Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G LRY L G D F +++ +G LF LD + + F++ V
Sbjct: 525 ITASDLDDGTIGQLRYSL-EGLDFPFF-INATSGDLFTVSALDRET---VPFYRFLVIVS 579
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
PL ++ A V + + D+NDN P F Y +I L G V VMA D D
Sbjct: 580 DGHPTMPLSSSAA-VVVTIEDVNDNFPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVEL 638
Query: 338 NGEFTYQLDDPKG-AFSIDPRSGWLTV 363
N + + L FSI+ +G + +
Sbjct: 639 NAKLNFSLQGQHAHLFSINSHTGTVLI 665
Score = 47.2 bits (107), Expect = 0.003
Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 12/145 (8%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LF L+ +G L + LD + E ++L A ++ L + RV ++++NDN
Sbjct: 31 LFLLNPHSGEFLLSRALDFEIERY-----YILTAGAQHGDSEL--IRVRVYFNVINVNDN 83
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P F + + SI E+ P G L + +D D+G GE + D + FSI+ + G
Sbjct: 84 PPVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELAVTSGDLENKFSIN-QEGT 142
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKE 385
L + + LDRE ++ + V A +
Sbjct: 143 LCLIAE--LDRETNAMYSLIVQAND 165
Score = 44.4 bits (100), Expect = 0.024
Identities = 57/226 (25%), Positives = 99/226 (43%), Gaps = 25/226 (11%)
Query: 930 DVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK 989
+ D + + + E+I IGT+I K+ A+D D L R+ + S + +
Sbjct: 1540 EFDSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWS-RFSY-----------SIEHGNIN 1587
Query: 990 RYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVF 1045
F+I+ G + V L E + + L + A+D G ++ + V + V D+ND P
Sbjct: 1588 SSFIIDPVSGVISVNSHLDREIWAIYNLTVIAVDEGSPSVTGSTKVAITVNDINDSPPKL 1647
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTYF-IQPSDTDLPFEISPLTGVLS 1103
T F + E Q ++ + ATD D N TY+ ++P++ F ++ GVL
Sbjct: 1648 LTT-EGF-IRENQPADTLVSTLTATDDDLPPNQGPFTYWMMRPAE---GFSLT-TEGVLV 1701
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ DRE + + + +V +D G D NDN+P
Sbjct: 1702 TSKPFDREHDPLFHMHIVVQDAG-KPPMSSTTLFHIKVLDENDNAP 1746
Score = 42.7 bits (96), Expect = 0.075
Identities = 72/305 (23%), Positives = 125/305 (40%), Gaps = 25/305 (8%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDI 144
+Y+ +V +N PI V DE G A I IG + P ++ +
Sbjct: 917 IYVTEVPENAPIGFSVIQIVATDE--DAGLNAVIEYTI-IGHNSEFPFSIDKTTGTLFVS 973
Query: 145 RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMA 203
DR+ + HY + +D +++ + + + D + F Q V
Sbjct: 974 HPLDREDQD------HYIVKVNANDSAWSISTD-----VTIDITDVNDNAPIFSQPVYSV 1022
Query: 204 SGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
+ + +F + A D+DLG A + Y + N+ LF +++ G + ++ + L A
Sbjct: 1023 TIPEMKMHEVFILQVSATDRDLGENAQVLYFINPPNE--LFFVNASTGEISNKQTIAL-A 1079
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
E L++ F V AS N + + V + L+ N P F +SI L G
Sbjct: 1080 E--LESEIFTFMVVASDCGNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGS 1137
Query: 324 SVLQVMATDKDQGE-NGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
V+QV A D+D + N Y G+ F ++ SG + V N T L + L ++
Sbjct: 1138 EVIQVSAVDQDYLQMNNSVEYFNSGGNGSLYFQVEQNSGRVLV-NAT-LANSLNMILTLE 1195
Query: 381 VYAKE 385
+ AK+
Sbjct: 1196 ITAKD 1200
Score = 39.5 bits (88), Expect = 0.69
Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 19/142 (13%)
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGT 1314
PVF + I E+ + +SLN+++ E L D+ F I+ + GT
Sbjct: 85 PVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVE-LAVTSGDLENKFSIN-QEGT 142
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
L L+ DRE Y +IV+A LP E V V + +KDVN
Sbjct: 143 LCLIAELDRETNAMYSLIVQAN----DHALP----------TETRLSSSVHVTIYLKDVN 188
Query: 1375 DNSPKFTNGNRPLVTAIPTTAP 1396
DN P T P + P AP
Sbjct: 189 DNPPFITT---PSTVSFPENAP 207
Score = 37.9 bits (84), Expect = 2.1
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 22/194 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE I++++A D D G N Q+ Y N PP++L F +N G
Sbjct: 1024 IPEMKMHEVFILQVSATDRDLGENAQVLYFIN-----PPNEL----------FFVNASTG 1068
Query: 1000 HVIVARSLPP---ESE-FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ +++ ESE F + A D GN LN + V V + N P+F +
Sbjct: 1069 EISNKQTIALAELESEIFTFMVVASDCGNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVS 1128
Query: 1054 VEEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ + +V A D D+ Q N ++ YF + L F++ +G + VN L
Sbjct: 1129 IPLTLDVGSEVIQVSAVDQDYLQMNNSVEYFNSGGNGSLYFQVEQNSGRVLVNATLANSL 1188
Query: 1113 EDKYILTVVARDNG 1126
L + A+D G
Sbjct: 1189 NMILTLEITAKDKG 1202
>UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor
suppressor homolog 1 (Drosophila),; n=3; Danio rerio|Rep:
PREDICTED: similar to FAT tumor suppressor homolog 1
(Drosophila), - Danio rerio
Length = 1402
Score = 131 bits (316), Expect = 2e-28
Identities = 157/583 (26%), Positives = 244/583 (41%), Gaps = 82/583 (14%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLL 677
F + SGVI+V L R A Q+N + S NA V V+ DV+D
Sbjct: 179 FEINPNSGVISVTTALDREEIDQITLYIQAAQQN-DPSKTANAVVSVIIEDVDDNSP--- 234
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSI-YGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K I + ENS + T ++ + G G +R + + +I DG
Sbjct: 235 KFDQEEYIISIPENSPKDQF--VLQTIVTDLDLGGFVGTLRIIPDSVP-----FSINPDG 287
Query: 737 TIFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
I ++P LDRE ++ V A+ N + VTI + DENDN P F + YEG
Sbjct: 288 RILVKRPEDLDRETTAIFSFQVEAQENPPS-TNKETADVTIILLDENDNSPQFTDSEYEG 346
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSL 853
+ + +G E+ ++ATD DEG NA Y + FG K F ++E G + +
Sbjct: 347 KVYADQTVGMEVVK---VEATDLDEGPNAEISYFIEFGNEKGFFGLNEKDGAITLVQLIP 403
Query: 854 DREKKIM-YKLSLVARDTGGLSSEAELIIMIGDENDNKPEF------NQIEENSK----- 901
E +I+ + L + ARD G +S ++ I D+ P+F Q+EEN +
Sbjct: 404 LVENEILEFALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVEENQEDAEIV 463
Query: 902 --------------VRIHRETKLNGTAGFTIIEVKPKNKFA-----LDVDQLGPLF---- 938
+ + E K + T +I + +++ + LDV+ P F
Sbjct: 464 KVNFLSIDPFVPVTLTVETEEKSSYTVLLSISDGTNRDEASVLVEVLDVNDNSPEFEDHP 523
Query: 939 ---LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
I EN +G + + A D D+G N +++Y L F I+
Sbjct: 524 PTVSISENHIVGEDVASVKATDADAGFNAEVQYTL---------------LGGAGRFNID 568
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ G + +A L E+ E+ L I+ D G +L+ + + V D+ND+ P+F K Y
Sbjct: 569 QETGVITLAAPLDREAQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYE 628
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGEL 1108
+ E + V ATD D G NA +++ I QPS F I +G +++ G+L
Sbjct: 629 TTMFEDADVGADVVVVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGKL 688
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D +Y L V RD G DVND P F
Sbjct: 689 DYSKAKRYTLDVEGRDGG-SPSLTGSAVVIVWVEDVNDKPPVF 730
Score = 118 bits (283), Expect = 2e-24
Identities = 123/435 (28%), Positives = 202/435 (46%), Gaps = 70/435 (16%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G I PLDRE +D Y + + + ++G S + + I + D NDN P+F YE
Sbjct: 570 ETGVITLAAPLDREAQDEYHLVITVQ-DQGRPSLSTTTDLGITVTDINDNSPIFSKQQYE 628
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDENTGVVKFI 849
+ E++ +G ++ ++ ATD D+G NA+ + + + +F++D ++G V
Sbjct: 629 TTMFEDADVGADVV---VVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLA 685
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
G LD K Y L + RD G L+ A +I+ + D ND P F++ E + V I+ E
Sbjct: 686 G-KLDYSKAKRYTLDVEGRDGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYD--VSIY-E 741
Query: 908 TKLNGTAGFTIIEVKPKNKF-------------------ALDVDQLGPLFL-IPENIPIG 947
GTA +EV ++K LD++ P FL +PE I I
Sbjct: 742 NLAGGTA-LVSLEVTDEDKVVAVDQPVDGLRSTAQVIITVLDINDNNPQFLPLPELIEIQ 800
Query: 948 T---------TIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ K++A D D G NG + + +S ++F ++
Sbjct: 801 EGKYTQSSPGEVCKISATDADIGDNGLVTFSTSS---------------YSKFFSCSD-D 844
Query: 999 GHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFN- 1053
G + L E + + + I+A+D G LN+ +VRV + DVND+ PVF Y+ +
Sbjct: 845 GTLQAISELDREMQDVYDVVITAVDHGIPQLNNMTTVRVSITDVNDNAPVFSSETYSRSI 904
Query: 1054 -VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
V +A+ +L V ATD D G NA +TY S+ + TG +++ +L T
Sbjct: 905 LVRDAKVGELLL-TVSATDRDAGDNALITYSF--SEVSSMVALDAETGDITLTSDLSEVT 961
Query: 1113 EDKYI-LTVVARDNG 1126
ED + L+ +A D+G
Sbjct: 962 EDTLLTLSAIATDHG 976
Score = 116 bits (280), Expect = 4e-24
Identities = 120/405 (29%), Positives = 176/405 (43%), Gaps = 40/405 (9%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V + + D NDN P FE I EN +G ++ +KATDAD G NA YTL G
Sbjct: 505 VLVEVLDVNDNSPEFEDHPPTVSISENHIVGEDVAS---VKATDADAGFNAEVQYTLLG- 560
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK 890
G F++D+ TGV+ + LDRE + Y L + +D G LS+ +L I + D NDN
Sbjct: 561 GAGRFNIDQETGVIT-LAAPLDREAQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNS 619
Query: 891 PEFNQIE------ENSKV--------RIHRETKLNGTAGFTIIEVKPKNK---FALDVDQ 933
P F++ + E++ V ++ +N F I+ +P + F +D D
Sbjct: 620 PIFSKQQYETTMFEDADVGADVVVVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDS 679
Query: 934 LGPLFLIPENIPIGTTIIKLNALDLDSG---LNGQ-IRYEFNSEVYIPPSKLSADALEVK 989
G + L + L+ D G L G + + +V P S D +V
Sbjct: 680 -GSVTLAGKLDYSKAKRYTLDVEGRDGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYDVS 738
Query: 990 RYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
Y N G +V+ + E + +DG L V + V D+ND+ P F
Sbjct: 739 IYE--NLAGGTALVSLEVTDEDKVVAVDQPVDG--LRSTAQVIITVLDINDNNPQFLPLP 794
Query: 1050 YNFNVEEAQYTRRVLG---KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
++E +YT+ G K+ ATDAD G N +T+ S F S G L
Sbjct: 795 ELIEIQEGKYTQSSPGEVCKISATDADIGDNGLVTF--STSSYSKFFSCSD-DGTLQAIS 851
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
ELDRE +D Y + + A D+G DVNDN+P F
Sbjct: 852 ELDREMQDVYDVVITAVDHG-IPQLNNMTTVRVSITDVNDNAPVF 895
Score = 104 bits (250), Expect = 2e-20
Identities = 162/696 (23%), Positives = 283/696 (40%), Gaps = 76/696 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A ++Y L+ G R F++D G + L LD +A+ + + L +
Sbjct: 541 VKATDADAGFNAEVQYTLLGGAGR--FNIDQETGVITLAAPLDREAQ-----DEYHLVIT 593
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
P + + I + D+NDN P F Y ++ E+ G V+ VMATDKD G
Sbjct: 594 VQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVVVMATDKDDGV 653
Query: 338 NGEFTYQL--DDPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVV 391
N ++ + P F+ID SG +T+ + LD + V ++ +PS+
Sbjct: 654 NAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGK--LDYSKAKRYTLDVEGRDGGSPSLT 711
Query: 392 GTFADSQRIAKWRRQPLETNAPLEKTTY---VFPDKV-GTKTENIEYYDEQ--------- 438
G S + W + K Y ++ + GT ++E DE
Sbjct: 712 G----SAVVIVWVEDVNDKPPVFSKDEYDVSIYENLAGGTALVSLEVTDEDKVVAVDQPV 767
Query: 439 --LMSFVNVEVTLLDANDNNPVFVP-SNLYEFSM-KSNAKVGTVIGKVKAVDPDLGQNGM 494
L S V +T+LD NDNNP F+P L E K + K+ A D D+G NG+
Sbjct: 768 DGLRSTAQVIITVLDINDNNPQFLPLPELIEIQEGKYTQSSPGEVCKISATDADIGDNGL 827
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLA 553
V + S F + + +++E ++ + + + A D + + ++
Sbjct: 828 VTFSTSSYSKF-----FSCSDDGTLQAISELDREMQDVYDVVITAVD---HGIPQLNNMT 879
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V + +T N P E + S + VG++ + + D + L
Sbjct: 880 TVRVSIT-DVNDNAPVFSS------ETYSRSILVRDAKVGELLLTVSATDRDAGDNALIT 932
Query: 614 Y---EEGVPFAVEERSGVITVVDDLSRYNR-PMYDFEAVALQENA-NLSIVTNATVHVVD 668
Y E A++ +G IT+ DLS + A+A LS +H
Sbjct: 933 YSFSEVSSMVALDAETGDITLTSDLSEVTEDTLLTLSAIATDHGTPALSDEAEVLIHFKI 992
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ V + S F +KEN I + ++ G+ V + + + +DV
Sbjct: 993 ASLSESVSFES--SSYNFMIKENEPEETI----VGTVKALTGSPLVTVNYNMKSHEDV-- 1044
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN-PPVF 787
++ +GTI K LD+E + Y +TV A ++ + A + T+ ++ EN N P F
Sbjct: 1045 -FSVDAEGTIQALKSLDKEDVEWYILTVEAIDSRTPPNTA---ETTVSVQVENVNEAPEF 1100
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ Y I + I ++ATD D ++ Y+L + + DV+ +TG +
Sbjct: 1101 DAEKYTAEIFNIAPYKFPIVK---VQATDPDVDESSKLQYSLV-KPTTVLDVEASTGQLY 1156
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ S + + Y++ A D GL + + I +
Sbjct: 1157 VLDASSIVDPLVTYEVK--ATDKHGLFTTTAVEITV 1190
Score = 86.6 bits (205), Expect = 5e-15
Identities = 125/488 (25%), Positives = 207/488 (42%), Gaps = 60/488 (12%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS++ +G + +++ DLD E F QV+A + A V I LLD NDN
Sbjct: 281 FSINP-DGRILVKRPEDLDRETTA---IFSFQVEAQENPPSTNKETADVTIILLDENDNS 336
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY--QLDDPKGAFSIDPRSGWL 361
P+F Y + + G V++V ATD D+G N E +Y + + KG F ++ + G +
Sbjct: 337 PQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEFGNEKGFFGLNEKDGAI 396
Query: 362 T-------VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA--DS--QRIAKWRRQPLET 410
T V N+ +L+ + + R + P++V A DS Q + K + +E
Sbjct: 397 TLVQLIPLVENE-ILEFALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVEE 455
Query: 411 N---APLEKTTYVFPDKVGTKTENIEYYDEQ----LMSF--------VNVEVTLLDANDN 455
N A + K ++ D T +E ++ L+S +V V +LD NDN
Sbjct: 456 NQEDAEIVKVNFLSIDPFVPVTLTVETEEKSSYTVLLSISDGTNRDEASVLVEVLDVNDN 515
Query: 456 NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
+P F + S+ N VG + VKA D D G N V Y L L F I+
Sbjct: 516 SPEF-EDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTL-----LGGAGRFNIDQ 569
Query: 516 NTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
TG +++A +P+ + + L + DQ L + ++ + P
Sbjct: 570 ETGVITLA-APLDREAQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNS-------PI 621
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGY-EEGVP-FAVEERSGV 628
F YE + + +G V + D + + VS+ +++ P F ++ SG
Sbjct: 622 FSKQQYETTMFEDADVGADVVVVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSGS 681
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDERGVLLKGAHSPIIF 686
+T+ L Y + V ++ + S+ +A V V DVND+ V K + I+
Sbjct: 682 VTLAGKLDYSKAKRYTLD-VEGRDGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYDVSIY 740
Query: 687 HVKENSAG 694
EN AG
Sbjct: 741 ---ENLAG 745
Score = 84.2 bits (199), Expect = 2e-14
Identities = 88/310 (28%), Positives = 134/310 (43%), Gaps = 22/310 (7%)
Query: 984 DALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFP 1043
DA VK F+ + V + +S + + +S DG N D SV V V DVND+ P
Sbjct: 459 DAEIVKVNFLSIDPFVPVTLTVETEEKSSYTVLLSISDGTN-RDEASVLVEVLDVNDNSP 517
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F+ ++ E + V ATDAD G NA + Y + F I TGV++
Sbjct: 518 EFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTLLGGAGR--FNIDQETGVIT 575
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD---ELLEW 1160
+ LDRE +D+Y L + +D G D+NDNSP F + E
Sbjct: 576 LAAPLDREAQDEYHLVITVQDQGRPSLSTTTDLGITVT-DINDNSPIFSKQQYETTMFED 634
Query: 1161 KHPEADE---LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
AD ++ + V + + I P T +D+ + G + YS
Sbjct: 635 ADVGADVVVVMATDKDDGVNAVVSFH--IVNQQPSSDTPVFNIDSDSGSVTLA-GKLDYS 691
Query: 1218 LPQRKNQ----QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
+R ++ G PSL+ +A+++V V DV D+ PVF Y++ I EN+
Sbjct: 692 KAKRYTLDVEGRDGGSPSLTGSAVVIVWVEDVNDK-----PPVFSKDEYDVSIYENLAGG 746
Query: 1274 VELVSLNLTE 1283
LVSL +T+
Sbjct: 747 TALVSLEVTD 756
Score = 82.2 bits (194), Expect = 1e-13
Identities = 64/189 (33%), Positives = 92/189 (48%), Gaps = 6/189 (3%)
Query: 209 HKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN-GSLFLEKELDLDAEHNL 267
H + PE I A D D G+ + Y L + + S +N S + LD E
Sbjct: 141 HFSDVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDRE--- 197
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ + L +QA+Q N+P KTA A V + + D++DN P+F+ + Y ISI EN P VLQ
Sbjct: 198 EIDQITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQ 257
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
+ TD D G T ++ FSI+P G + V+ LDRE + +V A+E
Sbjct: 258 TIVTDLDLG-GFVGTLRIIPDSVPFSINP-DGRILVKRPEDLDRETTAIFSFQVEAQENP 315
Query: 388 PSVVGTFAD 396
PS AD
Sbjct: 316 PSTNKETAD 324
Score = 78.6 bits (185), Expect = 1e-12
Identities = 117/508 (23%), Positives = 211/508 (41%), Gaps = 51/508 (10%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ---YTRRVLGKVD 1068
++ + A D G L+D +V + + D ++ P F + Y +EE + ++ +
Sbjct: 92 QYTFTVKAQDTGGLSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVTPEAIK 151
Query: 1069 ATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
A D D G N + Y + P++ FEI+P +GV+SV LDRE D+ L + A
Sbjct: 152 AQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQ 211
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
DV+DNSPKF + ++ PE ++++
Sbjct: 212 N-DPSKTANAVVSVIIEDVDDNSPKFDQEEYII--SIPENSPKDQFVLQTIV------TD 262
Query: 1186 IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTA-----ILMV 1240
++ +GT ++ + F N +G IL P+ +++ + S A
Sbjct: 263 LDLGGFVGT--LRIIPDSVPFSINPDGRILVKRPEDLDRETTAIFSFQVEAQENPPSTNK 320
Query: 1241 TVADVPDEV--EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILN 1296
ADV + E + P F YE ++ + +E+V + T+ E N ++ Y+I
Sbjct: 321 ETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEF 380
Query: 1297 ENDTDIRRTFVIDPRNGTLYLVR---SPDREVKDTYEVIVRAERQKYSRELPHMIYPVA- 1352
N+ + F ++ ++G + LV+ + E+ + I + SR P +++ A
Sbjct: 381 GNE---KGFFGLNEKDGAITLVQLIPLVENEILEFALYITARDGGAISRSTPALVHIQAP 437
Query: 1353 -EDVLEGMTK-YDVKVVVRIKDVNDNSPKFTNGNR--PLVTAIPTTAPFGYQVMQLKGAI 1408
+ + + K Y +V +D F + + P+ + T Y V+
Sbjct: 438 GDSHPQFLQKTYQGQVEENQEDAEIVKVNFLSIDPFVPVTLTVETEEKSSYTVLLSISDG 497
Query: 1409 GHHPTASRTVRA--DTDELVFFE------RLSLN-----GLTSPQATDSDIGINADIRYQ 1455
+ AS V D FE +S N + S +ATD+D G NA+++Y
Sbjct: 498 TNRDEASVLVEVLDVNDNSPEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYT 557
Query: 1456 ILNEQAPRFAIDPVSGTVRVVAALARDA 1483
+L A RF ID +G + + A L R+A
Sbjct: 558 LLG-GAGRFNIDQETGVITLAAPLDREA 584
Score = 75.4 bits (177), Expect = 1e-11
Identities = 73/264 (27%), Positives = 118/264 (44%), Gaps = 15/264 (5%)
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
G+ + K + A D D+ PN+++ Y I GN+ G F L + L++ + + E
Sbjct: 355 GMEVVK-VEATDLDEG--PNAEISYFIEFGNEKGFFGLNEKDGAITLVQLIPLVENEILE 411
Query: 197 FQLVIMA-SGKRIHKEILFPEPIHAIDQDLGVGATLRYE-LISGN--DRKLFSLDSVNGS 252
F L I A G I + I A Y+ + N D ++ ++ ++
Sbjct: 412 FALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVEENQEDAEIVKVNFLSID 471
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
F+ L ++ E + +++ + + S N +A V +E+LD+NDN PEFE
Sbjct: 472 PFVPVTLTVETE---EKSSYTVLLSISDGTN---RDEASVLVEVLDVNDNSPEFEDHPPT 525
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+SI EN G V V ATD D G N E Y L G F+ID +G +T+ LDRE
Sbjct: 526 VSISENHIVGEDVASVKATDADAGFNAEVQYTLLGGAGRFNIDQETGVITL--AAPLDRE 583
Query: 373 AHSSLRMKVYAKETNPSVVGTFAD 396
A + + ++ + T D
Sbjct: 584 AQDEYHLVITVQDQGRPSLSTTTD 607
Score = 73.3 bits (172), Expect = 5e-11
Identities = 69/255 (27%), Positives = 108/255 (42%), Gaps = 18/255 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGV 628
P+F P + N +G V ++ DA +V Y LL G F +++ +GV
Sbjct: 517 PEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTLLGGAGR---FNIDQETGV 573
Query: 629 ITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
IT+ L R + Y V Q +LS T+ + V D+ND + K + +F
Sbjct: 574 ITLAAPLDREAQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMF- 632
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---AEDGTIFTQKPL 744
++ GA + + T+ V F I NQQ +D ++ G++ L
Sbjct: 633 -EDADVGADVVVVMATDKDD---GVNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGKL 688
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
D K Y + V + G S G V +++ED ND PPVF Y+ I EN GT
Sbjct: 689 DYSKAKRYTLDVEGR-DGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYDVSIYENLAGGT 747
Query: 805 EIKMDNIIKATDADE 819
+ ++ TD D+
Sbjct: 748 ALVS---LEVTDEDK 759
Score = 67.3 bits (157), Expect = 3e-09
Identities = 52/181 (28%), Positives = 85/181 (46%), Gaps = 10/181 (5%)
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
Q +D + DG I K L+ Y TV A+ G+ VTI I D ++
Sbjct: 64 QPPAPEDFDVRSDGNIRLLKHLNYNNIQQYTFTVKAQDTGGLSDTTA---VTITIVDYDN 120
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFD 838
P F+H+ Y+ I EN IKA D D G N +Y+L E + F+
Sbjct: 121 LNPYFDHSLYKATIEENEIGHFSDVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFE 180
Query: 839 VDENTGVVKFIGDSLDREK--KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
++ N+GV+ + +LDRE+ +I + ++ ++ A + ++I D +DN P+F+Q
Sbjct: 181 INPNSGVIS-VTTALDREEIDQITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQE 239
Query: 897 E 897
E
Sbjct: 240 E 240
Score = 65.7 bits (153), Expect = 9e-09
Identities = 103/408 (25%), Positives = 171/408 (41%), Gaps = 81/408 (19%)
Query: 946 IGTTIIKLNALDLDSGLNGQIRY--EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIV 1003
+G ++K+ A DLD G N +I Y EF +E K +F +NE+ G + +
Sbjct: 354 VGMEVVKVEATDLDEGPNAEISYFIEFGNE---------------KGFFGLNEKDGAITL 398
Query: 1004 ARSLPPES----EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ +P EF L I+A DGG ++ + V ++ D P F + Y VEE Q
Sbjct: 399 VQLIPLVENEILEFALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVEENQE 458
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++ KV+ D LT +T+ E S T +LS++ +R+ E ++
Sbjct: 459 DAEIV-KVNFLSIDPFVPVTLTV-----ETE---EKSSYTVLLSISDGTNRD-EASVLVE 508
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF--ESVM 1177
V+ DVNDNSP+F HP +S ++ E V
Sbjct: 509 VL---------------------DVNDNSPEFE--------DHPPTVSISENHIVGEDVA 539
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQ---------QNL 1227
+ A NA + T+ I G+I + P R+ Q Q+
Sbjct: 540 SVKATDADAGFNAEVQYTLLGGAGRFN--IDQETGVITLAAPLDREAQDEYHLVITVQDQ 597
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G PSLS+T L +TV D+ D + P+F + YE + E+ + ++V + T+ +
Sbjct: 598 GRPSLSTTTDLGITVTDIND-----NSPIFSKQQYETTMFEDADVGADVVVVMATDKDDG 652
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
N + ++I+N+ + F ID +G++ L D Y + V
Sbjct: 653 VNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDV 700
Score = 56.0 bits (129), Expect = 7e-06
Identities = 83/375 (22%), Positives = 157/375 (41%), Gaps = 29/375 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG----TVIGKVKAVDPDLGQNGMVLYDLQ 500
V +T++D ++ NP F S LY+ +++ N ++G +KA D D G N V+Y L
Sbjct: 111 VTITIVDYDNLNPYFDHS-LYKATIEEN-EIGHFSDVTPEAIKAQDGDTGINEPVVYSLT 168
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
S F+INPN+G +SV + E + L+++A+ Q +PS+ ++ V IE
Sbjct: 169 TVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQ-NDPSKTANAVVSVIIE 227
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ P F Y + N V Q V D V L + V
Sbjct: 228 DV------DDNSPKFDQEEYIISIPENSPKDQFVLQTIVTDLDLGGFVG--TLRIIPDSV 279
Query: 619 PFAVEERSGVITV-VDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDVNDERGV 675
PF++ ++ +DL R ++ F+ V QEN + + T+ ++D ND
Sbjct: 280 PFSINPDGRILVKRPEDLDRETTAIFSFQ-VEAQENPPSTNKETADVTIILLDENDNSPQ 338
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ ++ + + G + ++ T++ + + I + +D
Sbjct: 339 FTDSEYEGKVY--ADQTVGMEVVKVEATDLDE---GPNAEISYFIEFGNEKGFFGLNEKD 393
Query: 736 GTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I + + + ++ + I + G IS + ++I+ D+ P F TY+G
Sbjct: 394 GAITLVQLIPLVENEILEFALYITARDGGAISRS--TPALVHIQAPGDSHPQFLQKTYQG 451
Query: 795 FIMENSKIGTEIKMD 809
+ EN + +K++
Sbjct: 452 QVEENQEDAEIVKVN 466
Score = 54.4 bits (125), Expect = 2e-05
Identities = 83/340 (24%), Positives = 139/340 (40%), Gaps = 35/340 (10%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES- 1011
+ A D D+G+N + Y + + P++ ++ F IN G + V +L E
Sbjct: 150 IKAQDGDTGINEPVVYSLTT---VLPNEYQSN-------FEINPNSGVISVTTALDREEI 199
Query: 1012 -EFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+ L I A + + N V V ++DV+D+ P F + Y ++ E + + +
Sbjct: 200 DQITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTI 259
Query: 1069 ATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE-LDRETEDKYILTVVARDNGX 1127
TD D G I S +PF I+P +L E LDRET + V A++N
Sbjct: 260 VTDLDLGGFVGTLRIIPDS---VPFSINPDGRILVKRPEDLDRETTAIFSFQVEAQENPP 316
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE 1187
D NDNSP+F D E K AD+ + ++ V ++
Sbjct: 317 STNKETADVTIILL-DENDNSPQFT--DSEYEGK-VYADQTVG-----MEVVKVEATDLD 367
Query: 1188 ENAPIGTTVAKVFANDTDFIG----NGNGLILYSLPQRKNQQ---NLGLPSLSSTAILMV 1240
E + F N+ F G +G ++ +P +N+ L + + AI
Sbjct: 368 EGPNAEISYFIEFGNEKGFFGLNEKDGAITLVQLIPLVENEILEFALYITARDGGAISRS 427
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
T A V + P F+ + Y+ ++EEN E+V +N
Sbjct: 428 TPALVHIQAPGDSHPQFLQKTYQGQVEEN-QEDAEIVKVN 466
>UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu
rubripes|Rep: Protocadherin 2G25 - Fugu rubripes
(Japanese pufferfish) (Takifugu rubripes)
Length = 950
Score = 131 bits (316), Expect = 2e-28
Identities = 129/468 (27%), Positives = 200/468 (42%), Gaps = 31/468 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E M F V V + D NDN P F + + + +A G KA+D D+G N +
Sbjct: 113 ENPMEFYTVTVEITDINDNPPTFERDEI-RYDISESALTGARFVLEKAIDDDVGLNSLKS 171
Query: 497 YDLQRTSNLTITSPFKINPNTGT--VSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
Y L+ + N + + +N G+ V + L+ + V + E + S
Sbjct: 172 YTLKPSDNFVLKT---VNRGDGSKHVEMVLQKQLDRENQNHVSLILTALDGGEPQLS-GT 227
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLH 612
+ I VT + P P Y+ V N IGT + + D E N+ V+Y +
Sbjct: 228 MQIIVTVLDANDNP--PVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISK 285
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G+ F ++ GV+T+ ++ R Y+ + V + + LS TV V D ND
Sbjct: 286 SGAAGL-FRIDATDGVLTLSGNVDYEKRKHYELD-VQVSDQGGLSDACRVTVDVTDTNDN 343
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + S V EN+ + I N+ N G V ++ T
Sbjct: 344 PPSINIMSKSQT---VSENTKPGTV--ITMLNVQDPDSNENGRVMCVLDENIHFTIRSTT 398
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
T+ T LDRE+ Y +TV ++GV S + +T+ I D NDNPPVFE ++Y
Sbjct: 399 NNFFTVITDSELDRERESEYNITVSCS-DEGVPSLSSSVTLTLQISDVNDNPPVFERSSY 457
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENTGVV 846
E +I+EN+ G + +KA DAD NA Y L V ++GVV
Sbjct: 458 EAYIVENNTPGLSV---FTVKARDADWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVV 514
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+ S D E+ + + A+D G LSS + I+I D+NDN P+
Sbjct: 515 HAV-RSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQ 561
Score = 113 bits (271), Expect = 5e-23
Identities = 122/472 (25%), Positives = 207/472 (43%), Gaps = 38/472 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL + + VT+LDANDN PV Y+ S++ NA +GT I V A D D G NG+V
Sbjct: 221 EPQLSGTMQIIVTVLDANDNPPVCSKPE-YKASVRENAPIGTRITTVSATDKDEGNNGIV 279
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y + ++ + F+I+ G ++++ + E R + L V+ SDQ R
Sbjct: 280 TYMISKSGAAGL---FRIDATDGVLTLSGNVDYEKRKHYELDVQVSDQGGLSDACR---- 332
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
VT++VT T N P I + M V N GT + + V D + N+ + ++
Sbjct: 333 -VTVDVT-DTNDNPPSI-NIMSKSQT--VSENTKPGTVITMLNVQDP-DSNE-NGRVMCV 385
Query: 614 YEEGVPFAVEE-RSGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
+E + F + + TV+ D L R Y+ E +LS T+ + DV
Sbjct: 386 LDENIHFTIRSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDV 445
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQD 725
ND V + ++ I V+ N+ G + +F N V +++ N
Sbjct: 446 NDNPPVFERSSYEAYI--VENNTPGLS---VFTVKARDADWNQNARVSYILEDSSVNGVP 500
Query: 726 VTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
V+ +++ A+ G + + D E+ + V A+ + G + V I I+D+NDNP
Sbjct: 501 VSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQ-DGGSPPLSSNVSVKILIQDQNDNP 559
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIK---ATDADEGTNALFMYTL-FGEGKEMFDVD 840
P + G M + + ++ A D D G NA Y L + +F+V
Sbjct: 560 PQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVG 619
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
G ++ I D++ + +LS++ D G S A +I+ + D+ PE
Sbjct: 620 LQNGEIRTIRQVTDKD-AVKQRLSVIVEDNGQPSRSATVIVNVA-VADSFPE 669
Score = 95.5 bits (227), Expect = 1e-17
Identities = 54/163 (33%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
QK LDRE ++ + ++ + G +G Q+ + + D NDNPPV Y+ + EN+
Sbjct: 199 QKQLDRENQNHVSL-ILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRENA 257
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKI 859
IGT I + ATD DEG N + Y + G +F +D GV+ G ++D EK+
Sbjct: 258 PIGTRI---TTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATDGVLTLSG-NVDYEKRK 313
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
Y+L + D GGLS + + + D NDN P N + ++ V
Sbjct: 314 HYELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMSKSQTV 356
Score = 85.4 bits (202), Expect = 1e-14
Identities = 134/530 (25%), Positives = 211/530 (39%), Gaps = 62/530 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFN-SEVYIPPSKLSADALEVKRYFVINERH 998
I E+ G + A+D D GLN Y S+ ++ + D +H
Sbjct: 144 ISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDG----------SKH 193
Query: 999 GHVIVARSLPPESEFRLNI--SALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+++ + L E++ +++ +ALDGG L+ + + V V D ND+ PV K Y +V
Sbjct: 194 VEMVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASV 253
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + V ATD D G N +TY I S F I GVL+++G +D E
Sbjct: 254 RENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATDGVLTLSGNVDYEKRK 313
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE---LLEWKHP-EADELSN 1170
Y L V D G D NDN P + + E P + N
Sbjct: 314 HYELDVQVSDQG---GLSDACRVTVDVTDTNDNPPSINIMSKSQTVSENTKPGTVITMLN 370
Query: 1171 HNFESVMMIPVYKATIEENA--PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLG 1228
++EN I +T F TD + Y++ + + G
Sbjct: 371 VQDPDSNENGRVMCVLDENIHFTIRSTTNNFFTVITDSELDRERESEYNITVSCSDE--G 428
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
+PSLSS+ L + ++DV D + PVF YE I EN + + ++ + N
Sbjct: 429 VPSLSSSVTLTLQISDVND-----NPPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQ 483
Query: 1289 KMRY-YILNE---NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
R YIL + N + + +G ++ VRS D E + +V+A+
Sbjct: 484 NARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQ----DGGS 539
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK----FTNGNRPLVTAIPTTAPFGYQ 1400
P P++ +V VK++ I+D NDN P+ G + +P +A GY
Sbjct: 540 P----PLSSNV-------SVKIL--IQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYL 586
Query: 1401 VMQLKGA---IGHHPTASRTVRADTDELVFFERLSLNG--LTSPQATDSD 1445
V ++ G + S ++ TD +F L NG T Q TD D
Sbjct: 587 VTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQ-NGEIRTIRQVTDKD 635
Score = 74.9 bits (176), Expect = 2e-11
Identities = 92/318 (28%), Positives = 136/318 (42%), Gaps = 29/318 (9%)
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTG 714
LS V V+D ND V K + V+EN+ G I + T+ GN G
Sbjct: 224 LSGTMQIIVTVLDANDNPPVCSKPEYKA---SVRENAPIGTRITTVSATDKDE--GNN-G 277
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
V ++I+ A DG + +D EKR Y + V ++G +S A +VT
Sbjct: 278 IVTYMISKSGAAGLFRIDATDGVLTLSGNVDYEKRKHYELDVQVS-DQGGLSDA--CRVT 334
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDNPP + + EN+K GT I M N+ D D N M L +
Sbjct: 335 VDVTDTNDNPPSINIMSKSQTVSENTKPGTVITMLNV---QDPDSNENGRVMCVL--DEN 389
Query: 835 EMFDVDENTG-VVKFIGDS-LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK 890
F + T I DS LDRE++ Y +++ D G LSS L + I D NDN
Sbjct: 390 IHFTIRSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNP 449
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI-GTT 949
P F E S + N T G ++ VK ++ D +Q + I E+ + G
Sbjct: 450 PVF----ERSSYEAY--IVENNTPGLSVFTVKARD---ADWNQNARVSYILEDSSVNGVP 500
Query: 950 IIKLNALDLDSGLNGQIR 967
+ ++ DSG+ +R
Sbjct: 501 VSSYVSVSADSGVVHAVR 518
Score = 74.1 bits (174), Expect = 3e-11
Identities = 50/164 (30%), Positives = 76/164 (46%), Gaps = 3/164 (1%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D+G+ + Y L ++ L +++ +GS +E L + Q N L + A
Sbjct: 159 AIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDGSKHVEMVLQKQLDRENQ-NHVSLILTAL 217
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + ++ + +LD NDN P Y S+ EN P G + V ATDKD+G NG
Sbjct: 218 DGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNG 277
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
TY + G F ID G LT+ ++ H L ++V
Sbjct: 278 IVTYMISKSGAAGLFRIDATDGVLTLSGNVDYEKRKHYELDVQV 321
Score = 72.1 bits (169), Expect = 1e-10
Identities = 65/222 (29%), Positives = 96/222 (43%), Gaps = 13/222 (5%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDRE 747
+E + GA IG + S+ +G R N ++ I + +D G + + +DRE
Sbjct: 39 EEMTKGAQIGNVAQDLGLSVERLKSGKARIYTGNTEEY---IELRQDKGVLLIKDRIDRE 95
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
M F + + Y VT+ I D NDNPP FE I E++ G
Sbjct: 96 ALCGQTMPCALHFQMILENPMEFYTVTVEITDINDNPPTFERDEIRYDISESALTGARFV 155
Query: 808 MDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
++ KA D D G N+L YTL K + D + V + LDRE + L
Sbjct: 156 LE---KAIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDGSKHVEMVLQKQLDRENQNHVSL 212
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
L A D G LS ++I+ + D NDN P ++ E + VR
Sbjct: 213 ILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVR 254
Score = 60.5 bits (140), Expect = 3e-07
Identities = 106/461 (22%), Positives = 182/461 (39%), Gaps = 61/461 (13%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ IPE + G I + A DL GL+ + + +Y ++ + + K +I +R
Sbjct: 35 YSIPEEMTKGAQIGNV-AQDL--GLSVERLKSGKARIYTGNTEEYIELRQDKGVLLIKDR 91
Query: 998 -HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ +++P F++ + N + +V V + D+ND+ P F++ +++ E
Sbjct: 92 IDREALCGQTMPCALHFQMILE-----NPMEFYTVTVEITDINDNPPTFERDEIRYDISE 146
Query: 1057 AQYT--RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG----VLSVNGELDR 1110
+ T R VL K A D D G N+ +Y ++PSD + ++ G + + +LDR
Sbjct: 147 SALTGARFVLEK--AIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDGSKHVEMVLQKQLDR 204
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E ++ L + A D G D NDN P
Sbjct: 205 ENQNHVSLILTALDGG-EPQLSGTMQIIVTVLDANDNPP--------------------- 242
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
V P YKA++ ENAPIGT + V A D D GN NG++ Y + GL
Sbjct: 243 -----VCSKPEYKASVRENAPIGTRITTVSATDKD-EGN-NGIVTYMI---SKSGAAGLF 292
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKM 1290
+ +T ++ +V D + + + + + + V++ N N
Sbjct: 293 RIDATDGVLTLSGNV-DYEKRKHYELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMS 351
Query: 1291 RYYILNEN---DTDIRRTFVIDP---RNGTLYLVRSPD-----REVKDTYEVIVRAERQK 1339
+ ++EN T I V DP NG + V + R + + ++
Sbjct: 352 KSQTVSENTKPGTVITMLNVQDPDSNENGRVMCVLDENIHFTIRSTTNNFFTVITDSELD 411
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
RE + I D V + ++I DVNDN P F
Sbjct: 412 RERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVF 452
Score = 60.5 bits (140), Expect = 3e-07
Identities = 52/199 (26%), Positives = 87/199 (43%), Gaps = 19/199 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+++ N P G ++ + A D D N ++ Y S + + V Y ++
Sbjct: 460 YIVENNTP-GLSVFTVKARDADWNQNARVSYILEDS--------SVNGVPVSSYVSVSAD 510
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V RS E +F + A DGG+ L+ N+SV++ ++D ND+ P
Sbjct: 511 SGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGG 570
Query: 1054 VEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
A+ R ++ KV A D D GQNA L+Y +Q + FE+ G + +
Sbjct: 571 SMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTIRQ 630
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ + K L+V+ DNG
Sbjct: 631 VTDKDAVKQRLSVIVEDNG 649
Score = 55.2 bits (127), Expect = 1e-05
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 7/164 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y + LF +D+ +G L L +D + + + L VQ
Sbjct: 266 VSATDKDEGNNGIVTYMISKSGAAGLFRIDATDGVLTLSGNVDYEKRKHYE-----LDVQ 320
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
S L A RV +++ D NDN P + + ++ EN G + + D D E
Sbjct: 321 VSDQGG-LSDA-CRVTVDVTDTNDNPPSINIMSKSQTVSENTKPGTVITMLNVQDPDSNE 378
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
NG LD+ + + TV + LDRE S + V
Sbjct: 379 NGRVMCVLDENIHFTIRSTTNNFFTVITDSELDRERESEYNITV 422
Score = 53.2 bits (122), Expect = 5e-05
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 244 FSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F++ S + F + + +LD E + N + V S P ++ + +++ D+NDN
Sbjct: 392 FTIRSTTNNFFTVITDSELDRERESEYN---ITVSCSDEGVPSLSSSVTLTLQISDVNDN 448
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
P FE Y IVEN G SV V A D D +N +Y L+D
Sbjct: 449 PPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILED 493
Score = 43.2 bits (97), Expect = 0.056
Identities = 59/240 (24%), Positives = 95/240 (39%), Gaps = 15/240 (6%)
Query: 208 IHKEILFPEPIHAIDQDLGVGATL----RYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
I +E+ I + QDLG+ + + +GN + L G L ++ +D +A
Sbjct: 37 IPEEMTKGAQIGNVAQDLGLSVERLKSGKARIYTGNTEEYIELRQDKGVLLIKDRIDREA 96
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
Q L Q L NP++ V +E+ D+NDN P FE D I E+ G
Sbjct: 97 LCG-QTMPCALHFQMI-LENPMEFYT--VTVEITDINDNPPTFERDEIRYDISESALTGA 152
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAF---SIDPRSGWLTVRN--QTVLDREAHSSLR 378
+ A D D G N +Y L P F +++ G V Q LDRE + +
Sbjct: 153 RFVLEKAIDDDVGLNSLKSYTL-KPSDNFVLKTVNRGDGSKHVEMVLQKQLDRENQNHVS 211
Query: 379 MKVYAKE-TNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDE 437
+ + A + P + GT + P + P K + +GT+ + D+
Sbjct: 212 LILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPIGTRITTVSATDK 271
Score = 39.5 bits (88), Expect = 0.69
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN---- 321
Q F V+A +P ++ V+I + D NDN P+ + V + E +P
Sbjct: 524 QIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADV 583
Query: 322 GFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREA 373
G+ V +V+A D D G+N +Y+L + F + ++G + Q V D++A
Sbjct: 584 GYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTIRQ-VTDKDA 636
>UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG3389-PA
- Tribolium castaneum
Length = 1870
Score = 130 bits (315), Expect = 2e-28
Identities = 261/1034 (25%), Positives = 429/1034 (41%), Gaps = 164/1034 (15%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + + + D NDN P+F N YE + N KV+A D DL NG +++ +
Sbjct: 595 VQLIINIEDVNDNPPIFT-QNRYEARLLENKLDFENPLKVEARDADL--NGTKNNEIEYS 651
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
++ F I P+TG I++ R ++ EA + S R+ L V + G
Sbjct: 652 LFGDLSHNFTIEPSTG--------IIKPRTSIDFEALEGSLKDSIRQLHLTVRARDW--G 701
Query: 563 TKGNKPDIPDFM-------GAP---YEFW---VGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
T D+P ++ AP Y F+ V ++ GTS+ Q+R D F+ + +
Sbjct: 702 TPSLFSDVPLYIYVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKD-FDGSSPNNR 760
Query: 610 LLHGYEEGVP--FAVEERSGVITVV------DDLSRYNRPMYDFEAVALQ----ENANLS 657
+++ + G F + SG+I+V DL++ Y VAL EN +
Sbjct: 761 IVYRIQNGASDKFIIAPESGIISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQA 820
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNG-TGN 715
VT V ++D+N++ V + P ++EN+A G+ I ++ ++ T N
Sbjct: 821 GVT-VNVTILDINNKNPVF----YEPGSVTMRENTAVGSVIAKLKAKDLDKTAQLVYTIN 875
Query: 716 VRFLIA-NQQDVT---DDIAIAE-------DGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
+F A N++ + D AE G + + LDRE + +M ++ E +
Sbjct: 876 PKFCEAKNERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVE-DTAS 934
Query: 765 ISGAGIYQ--VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
+G I +TI IED NDN P F Y+ I ENSK G + + N++ A DAD+ N
Sbjct: 935 ETGPQISTTTITINIEDINDNSPKFRQPYYKFSITENSKNG--VTIGNVL-AEDADK--N 989
Query: 823 ALFMYTLFG--EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAE 878
YTL G E E+ +D N+G + + + +D E L++ A D+G S E
Sbjct: 990 KTITYTLDGRFEITELIYLDSNSGDL-VVANKIDHEIYDWLNLTIKATDSGIPARFSRVE 1048
Query: 879 LIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF 938
+ I I DENDN P F + E + I +T + IIE K D + G +
Sbjct: 1049 IFIQILDENDNNPFF--LGEPQSLLISEDTPVGRQV--AIIEAKD-----ADSGEFGKIT 1099
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ + I ++D DSG+ L+V E+H
Sbjct: 1100 YLLDRISSEGKF----SIDADSGI-----------------------LKVSDKLDREEKH 1132
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+++V + ++ ++ + N +I+V + DVND+ P Y N+ E
Sbjct: 1133 SYLLVIEAW---DNYQYGFNSGESRNAFKHINVTIL--DVNDNHPQLHVPPYCVNITEFH 1187
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-----FEISPLTGVLSVNGELDRETE 1113
+ + A+DAD +N I SD + +IS + L L R
Sbjct: 1188 EPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFALSQISEWSAELRTTTSL-RGRH 1246
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y L + A+D G D ND+ P F + PE N
Sbjct: 1247 GNYTLIIRAQDLG-TPSHLIEEPLHICVTDFNDHPPTFVTPPHNSTLRVPE-----NATI 1300
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN-----GLILYSLP-QRKNQQ-- 1225
S ++ + AT E+ G ++ A+ + N G++ LP RK Q+
Sbjct: 1301 GSALVKII--ATDEDVGSNGIVRYRLKADPAGHWKSFNLQPVSGILELRLPLDRKKQKVY 1358
Query: 1226 -------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
+LG+PSLSS L V V+++ D +P F+ + + EN + VE
Sbjct: 1359 DIRIEAYDLGVPSLSSDLDLTVYVSNINDY-----QPQFMGDEFTVNFTENKPSEVERQK 1413
Query: 1279 LNLTEHYENFK-------MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
L T + + + Y+I+ N+ + F + P L + R DRE KDT+ +
Sbjct: 1414 LPQTVDRDELEFDGPFAPICYFIVGGNENGL---FKLHPVEHILTVSRPLDREEKDTHLL 1470
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAI 1391
+V+A P E + +KV+V++ DVNDN+P+F +R +
Sbjct: 1471 LVKATEDCTKP-------PRNESFFDSSDDTQLKVIVKVLDVNDNAPQFI--HRVFTGGV 1521
Query: 1392 PTTAPFGYQVMQLK 1405
T FG M++K
Sbjct: 1522 STATSFGTTFMEVK 1535
Score = 101 bits (243), Expect = 1e-19
Identities = 127/476 (26%), Positives = 211/476 (44%), Gaps = 45/476 (9%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+S + + + D NDN+P F Y+FS+ N+K G IG V A D D +N + Y L
Sbjct: 940 ISTTTITINIEDINDNSPKF-RQPYYKFSITENSKNGVTIGNVLAEDAD--KNKTITYTL 996
Query: 500 QRTSNLTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
IT ++ N+G + VA + I + + L ++A+D P+ R+S +
Sbjct: 997 D--GRFEITELIYLDSNSGDLVVANKIDHEIYDWLN-LTIKATDS-GIPA--RFSRVEIF 1050
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGY 614
I++ N P F+G P + + +G V I DA E ++Y L
Sbjct: 1051 IQILDENDNN----PFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRIS 1106
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVH----VV 667
EG F+++ SG++ V D L R + Y A Q N NA H ++
Sbjct: 1107 SEG-KFSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTIL 1165
Query: 668 DVNDERGVLLKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA--NQQ 724
DVND L P ++ E + G AI FH + + G V I+ NQ+
Sbjct: 1166 DVNDNHPQL---HVPPYCVNITEFHEPGQAI-TTFHASDADDPNTSNGQVIIDISDGNQK 1221
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ I+E R + Y + + A+ + G S + I + D ND+P
Sbjct: 1222 NFFALSQISEWSAELRTTTSLRGRHGNYTLIIRAQ-DLGTPSHLIEEPLHICVTDFNDHP 1280
Query: 785 PVFEHATYEGF--IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDV 839
P F + + EN+ IG+ + I ATD D G+N + Y L + + F++
Sbjct: 1281 PTFVTPPHNSTLRVPENATIGSALVK---IIATDEDVGSNGIVRYRLKADPAGHWKSFNL 1337
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+G+++ + LDR+K+ +Y + + A D G LSS+ +L + + + ND +P+F
Sbjct: 1338 QPVSGILE-LRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQF 1392
Score = 99.5 bits (237), Expect = 6e-19
Identities = 127/487 (26%), Positives = 196/487 (40%), Gaps = 44/487 (9%)
Query: 441 SFVNVEVTLL--DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
++V + LL D NDN P+F S+ +++ +A G VI ++A D D G G V+Y
Sbjct: 139 NYVTQSLLLLVEDVNDNTPIFT-SHQSSITLREDAAPG-VIATLEATDLDEGAYGQVVYQ 196
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAV 554
LQ T S F ++ G V L+ H L V A D+ + R +
Sbjct: 197 LQEVD--TKESLFSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRA---KQGRVNTGT 251
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
+ V ++P P+F+ + N IGTSV Q+ D N + Y L
Sbjct: 252 AALLVKVEDVEDQP--PEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSS 309
Query: 613 GYEEGVP--FAVEERSGVITVVDDLSRYNRPM----YDFEAVALQENANL----SIVTNA 662
+ + F++EE +G + L R + + Y + A + + S+ T
Sbjct: 310 NSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSVTTEV 369
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG---TGNVRFL 719
TV + D+NDE G + + EN+ + M +Y + G +
Sbjct: 370 TVIITDINDETPKFRSGYYE---CEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLY 426
Query: 720 IANQQDV---TDDIAIAEDGTIFTQKP---LDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ DV T AI E + K LD EK T++A+ V
Sbjct: 427 VKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVPV 486
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+I D NDN P F YE F+ EN IG + + GT + L G
Sbjct: 487 VAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGSI 546
Query: 834 KEMFDVDENTGVVKFI---GDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDEND 888
+ M ++ TG++ G + DRE+ + L++ ARD G + +LII I D ND
Sbjct: 547 QHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDVND 606
Query: 889 NKPEFNQ 895
N P F Q
Sbjct: 607 NPPIFTQ 613
Score = 94.7 bits (225), Expect = 2e-17
Identities = 130/498 (26%), Positives = 214/498 (42%), Gaps = 69/498 (13%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLY 497
L S V + + + D ND+ P+F Y S+ + GT I +V+A D D N ++Y
Sbjct: 705 LFSDVPLYIYVQDVNDHAPLF-EYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVY 763
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEG--------RHALFVEASDQPANPSERR 549
+Q ++ F I P +G +SVA L+ ++L V A D P E +
Sbjct: 764 RIQNGAS----DKFIIAPESGIISVARGASLDPDLTQPRTLHYSLNVVALD--GAPGENQ 817
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
A VT+ VT NK P F P + N +G+ + +++ D + + Y
Sbjct: 818 LQ-AGVTVNVTILDINNKN--PVFY-EPGSVTMRENTAVGSVIAKLKAKDLDKTAQLVYT 873
Query: 610 LLHGY-----EEGV-----------PFAVEERSGVITVVDDLSRYNRPMYDF----EAVA 649
+ + E G+ F + SGV+T+ L R E A
Sbjct: 874 INPKFCEAKNERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTA 933
Query: 650 LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSI 708
+ +S T T+++ D+ND + + F + ENS G IG + +
Sbjct: 934 SETGPQIS-TTTITINIEDINDNSPKFRQPYYK---FSITENSKNGVTIGNVLAEDADK- 988
Query: 709 YGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
N T + + + + ++T+ I + + G + +D E D +T+ A + G+ +
Sbjct: 989 --NKT--ITYTLDGRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKAT-DSGIPAR 1043
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
++ I I DENDN P F I E++ +G ++ II+A DAD G Y
Sbjct: 1044 FSRVEIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQVA---IIEAKDADSGEFGKITY 1100
Query: 828 TL---FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT---GGLSSEA---- 877
L EGK F +D ++G++K + D LDRE+K Y L + A D G S E+
Sbjct: 1101 LLDRISSEGK--FSIDADSGILK-VSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAF 1157
Query: 878 -ELIIMIGDENDNKPEFN 894
+ + I D NDN P+ +
Sbjct: 1158 KHINVTILDVNDNHPQLH 1175
Score = 89.0 bits (211), Expect = 9e-16
Identities = 124/494 (25%), Positives = 205/494 (41%), Gaps = 53/494 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D D P FV + NA +GT + +V A+D D G N +LY L S
Sbjct: 256 VKVEDVEDQPPEFVRVTSVA-RIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSNSIDR 314
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV-----VTIEVTR 561
IT F + TGT+ A++ L+ R +L + + + Y + VT EVT
Sbjct: 315 ITDVFSLEETTGTLLTAKT--LD-RESLSLSSGTYILQITATEYGGKIKPPPSVTTEVTV 371
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVP 619
+ P F YE + N + T + + + + ++ + Y +G
Sbjct: 372 IITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGAS 431
Query: 620 --FAVEERSGVITVVDDLSRYNRPMYDFEAVA-----------LQENANLSIVTNATVHV 666
F + + + N D+E + ++ N + V H+
Sbjct: 432 DVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVP-VVAHI 490
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ-------IFHTNMSSIYGNGTGNVRFL 719
+D ND K + + + A A Q +F T M Y + +G+++ +
Sbjct: 491 LDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGT-MGIRYTHLSGSIQHM 549
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ N T I++ G DRE+ + +TV A + G + + Q+ I IED
Sbjct: 550 L-NLHPTTGIISVKTAGG----PNWDREQISRHYLTVEARDDLGQGNRITV-QLIINIED 603
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGT-NALFMYTLFGEGKEMF 837
NDNPP+F YE ++EN K+ E + ++A DAD GT N Y+LFG+ F
Sbjct: 604 VNDNPPIFTQNRYEARLLEN-KLDFENPLK--VEARDADLNGTKNNEIEYSLFGDLSHNF 660
Query: 838 DVDENTGVVK----FIGDSLDREKKIMYK---LSLVARDTG--GLSSEAELIIMIGDEND 888
++ +TG++K ++L+ K + L++ ARD G L S+ L I + D ND
Sbjct: 661 TIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVND 720
Query: 889 NKPEFNQIEENSKV 902
+ P F N V
Sbjct: 721 HAPLFEYTFYNKSV 734
Score = 84.2 bits (199), Expect = 2e-14
Identities = 117/514 (22%), Positives = 203/514 (39%), Gaps = 49/514 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL + V V VT+LD N+ NPVF +M+ N VG+VI K+KA DL + +
Sbjct: 815 ENQLQAGVTVNVTILDINNKNPVFYEPG--SVTMRENTAVGSVIAKLKA--KDLDKTAQL 870
Query: 496 LYD--------------LQRTSNLTITSPFKINPNTGTVSVAE----SPILEGRHALFVE 537
+Y L + S+ F ++P +G +++A+ + + + L VE
Sbjct: 871 VYTINPKFCEAKNERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVE 930
Query: 538 ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV 597
+ P + S +TI + + + P F Y+F + N G ++G +
Sbjct: 931 DTASETGP---QISTTTITINI----EDINDNSPKFRQPYYKFSITENSKNGVTIGNVLA 983
Query: 598 NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSR--YNRPMYDFEAVALQENAN 655
DA + ++Y L +E ++ SG + V + + Y+ +A A
Sbjct: 984 EDADKNKTITYTLDGRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPAR 1043
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
S V + ++D ND L S +I ++ G + I + S G
Sbjct: 1044 FSRV-EIFIQILDENDNNPFFLGEPQSLLI--SEDTPVGRQVAIIEAKDADS---GEFGK 1097
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGA---GI 770
+ +L+ A+ G + LDRE++ Y + + A + G SG
Sbjct: 1098 ITYLLDRISSEGKFSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAF 1157
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+ + I D NDN P Y I E + G I + A D + + +
Sbjct: 1158 KHINVTILDVNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISD 1217
Query: 831 GEGKEMFDVDE-NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS--EAELIIMIGDEN 887
G K F + + + + + R + Y L + A+D G S E L I + D N
Sbjct: 1218 GNQKNFFALSQISEWSAELRTTTSLRGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFN 1277
Query: 888 DNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
D+ P F NS +R+ N T G ++++
Sbjct: 1278 DHPPTFVTPPHNSTLRVPE----NATIGSALVKI 1307
Score = 77.4 bits (182), Expect = 3e-12
Identities = 92/353 (26%), Positives = 151/353 (42%), Gaps = 49/353 (13%)
Query: 69 RIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE-----------LTPTGEKAF 117
R+G G N ++ S+ + +EDVNDN PIF +T+ E T E A+
Sbjct: 134 RLGHG-NYVTQ--SLLLLVEDVNDNTPIFTSHQSSITLREDAAPGVIATLEATDLDEGAY 190
Query: 118 ---IFLIAPIGPSLTI-PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFA 173
++ + + ++ ++ G I + + + D +K +H V D
Sbjct: 191 GQVVYQLQEVDTKESLFSVSTAGGKAIVRLVGSLDYEKQT-----LHQLKVLAVDRAKQG 245
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVI----MASGKRIHKEILFPEPIHAIDQDLGVGA 229
++ LL+ KV D + EF V +A I +L + AID D GV
Sbjct: 246 RVNTGTAALLV-KVEDVEDQPPEFVRVTSVARIAENAPIGTSVL---QVTAIDGDRGVNN 301
Query: 230 TLRYELISGN-DR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
+ Y L S + DR +FSL+ G+L K LD ++ +L + T++LQ+ A++ +K
Sbjct: 302 PILYSLSSNSIDRITDVFSLEETTGTLLTAKTLDRESL-SLSSGTYILQITATEYGGKIK 360
Query: 287 ---TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT-----DKDQGEN 338
+ V + + D+ND P+F +Y I EN P + + + D DQG N
Sbjct: 361 PPPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGIN 420
Query: 339 GEFTYQLDDPKGAFSIDPRSG------WLTVRNQTVLDREAHSSLRMKVYAKE 385
G F + F I P + V+N T LD E ++ + AKE
Sbjct: 421 GTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKE 473
Score = 70.5 bits (165), Expect = 3e-10
Identities = 119/483 (24%), Positives = 196/483 (40%), Gaps = 54/483 (11%)
Query: 437 EQLMSFVNVEVTLLDANDNNP-VFVPS---NLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
E +F ++ VT+LD NDN+P + VP N+ EF A T A DP+ N
Sbjct: 1152 ESRNAFKHINVTILDVNDNHPQLHVPPYCVNITEFHEPGQAI--TTFHASDADDPNTS-N 1208
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERR 549
G V+ D+ + + +I+ + + S L GRH L + A D PS
Sbjct: 1209 GQVIIDISDGNQKNFFALSQISEWSAELRTTTS--LRGRHGNYTLIIRAQDL-GTPSH-- 1263
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYE--FWVGSNVGIGTSVGQIRVNDA-FEQNDV 606
L + + + P P F+ P+ V N IG+++ +I D N +
Sbjct: 1264 --LIEEPLHICVTDFNDHP--PTFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGI 1319
Query: 607 SYDLLHGYEEG--VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNAT 663
L G F ++ SG++ + L R + +YD A +LS + T
Sbjct: 1320 VRYRLKADPAGHWKSFNLQPVSGILELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLT 1379
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSA--GAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
V+V ++ND + + G + F + S + Q + G F++
Sbjct: 1380 VYVSNINDYQPQFM-GDEFTVNFTENKPSEVERQKLPQTVDRDELEFDGPFAPICYFIVG 1438
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF-------NKGVISGAGIYQVT 774
++ + E + +PLDRE++D + + V A N+ + Q+
Sbjct: 1439 GNENGLFKLHPVEH-ILTVSRPLDREEKDTHLLLVKATEDCTKPPRNESFFDSSDDTQLK 1497
Query: 775 IYIE--DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG- 831
+ ++ D NDN P F H + G + + GT M+ +KA DAD NA Y L G
Sbjct: 1498 VIVKVLDVNDNAPQFIHRVFTGGVSTATSFGTTF-ME--VKAEDADLDDNARMSYFLIGK 1554
Query: 832 ------EG-----KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI 880
EG ++ F VD +TG V+ D + K + ++ DTGGL A +
Sbjct: 1555 VQMTLTEGLEDLKRDPFLVDRDTGAVQLNFDPQEGMKG-YFDFMVLVNDTGGLQDMARVF 1613
Query: 881 IMI 883
I +
Sbjct: 1614 IYL 1616
Score = 67.3 bits (157), Expect = 3e-09
Identities = 53/168 (31%), Positives = 85/168 (50%), Gaps = 10/168 (5%)
Query: 219 HAIDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ + +D T+ Y L + +L LDS +G L + ++D H + + L ++
Sbjct: 980 NVLAEDADKNKTITYTLDGRFEITELIYLDSNSGDLVVANKID----HEIY-DWLNLTIK 1034
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P + ++ + I++LD NDN P F + ++ I E+ P G V + A D D GE
Sbjct: 1035 ATDSGIPARFSRVEIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGE 1094
Query: 338 NGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
G+ TY LD +G FSID SG L V ++ LDRE S + + A
Sbjct: 1095 FGKITYLLDRISSEGKFSIDADSGILKVSDK--LDREEKHSYLLVIEA 1140
Score = 66.1 bits (154), Expect = 7e-09
Identities = 101/439 (23%), Positives = 172/439 (39%), Gaps = 67/439 (15%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+ ++ K LDRE RD Y + + + + + +ED NDN P+F
Sbjct: 107 EADVYLNKELDRETRDEYPLVLTLTDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSI 166
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ E++ G ++ ATD DEG +Y ++ +VD
Sbjct: 167 TLREDAAPGVIATLE----ATDLDEGAYGQVVY-------QLQEVDT------------- 202
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
K SL + T G + ++ ++G + K +Q++ + R + GTA
Sbjct: 203 -------KESLFSVSTAGGKA---IVRLVGSLDYEKQTLHQLKVLAVDRAKQGRVNTGTA 252
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
+++V+ + ++ + I EN PIGT+++++ A+D D G+N I Y +S
Sbjct: 253 AL-LVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSN- 310
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES------EFRLNISALD-GGNLND 1027
S D + F + E G ++ A++L ES + L I+A + GG +
Sbjct: 311 -------SID--RITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKP 361
Query: 1028 ----NISVRVFVKDVNDHFPVFKKTWYNFNVEE---AQYTRRVLGKVDATDADFGQNANL 1080
V V + D+ND P F+ +Y + E LG D Q N
Sbjct: 362 PPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGING 421
Query: 1081 TYFIQPSDTDLPFEISP------LTGVLSVNGE--LDRETEDKYILTVVARDNGXXXXXX 1132
T+ + FEI+P T ++ V LD E T+VA++
Sbjct: 422 TFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKF 481
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D NDN P+F
Sbjct: 482 NEVPVVAHILDRNDNYPEF 500
Score = 66.1 bits (154), Expect = 7e-09
Identities = 150/670 (22%), Positives = 253/670 (37%), Gaps = 88/670 (13%)
Query: 744 LDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LD EK+ ++++ V+A +G ++ G + + +ED D PP F T I EN+
Sbjct: 224 LDYEKQTLHQLKVLAVDRAKQGRVN-TGTAALLVKVEDVEDQPPEFVRVTSVARIAENAP 282
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
IGT + + A D D G N +Y+L +D T V SL+ +
Sbjct: 283 IGTSVLQ---VTAIDGDRGVNNPILYSLSSNS-----IDRITDVF-----SLEETTGTLL 329
Query: 862 KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
+ R++ LSS ++ + E K++ T T I
Sbjct: 330 TAKTLDRESLSLSSGTYIL-----------QITATEYGGKIKPPPSVTTEVTVIITDIND 378
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL-----DLDSGLNG--QIRYEFNSEV 974
+ KF + I EN P+ T + L + D D G+NG Q+ + S+V
Sbjct: 379 ETP-KFRSGYYECE----IAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGASDV 433
Query: 975 Y-IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDN-ISVR 1032
+ I P+K +A F+I ++ + + + F L + N N + V
Sbjct: 434 FEITPTKAINEAT-----FMIRVKNSTFLDYEKIKTIN-FTLVAKEIVKHNPKFNEVPVV 487
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG--QNANLTYFIQPSDTD 1090
+ D ND++P F K Y V E + V A D D G + Y
Sbjct: 488 AHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGSIQ 547
Query: 1091 LPFEISPLTGVLSV----NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ P TG++SV DRE ++ LTV ARD+ DVND
Sbjct: 548 HMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDD-LGQGNRITVQLIINIEDVND 606
Query: 1147 NSPKF-------YAFDELLEWKHP------EADELSNHNFE---SVMMIPVYKATIEENA 1190
N P F + L++++P +AD N E S+ + TIE +
Sbjct: 607 NPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDLSHNFTIEPST 666
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
I + + D + + + L ++ G PSL S L + V DV D
Sbjct: 667 GI---IKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDHA- 722
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
P+F +Y + E+++ ++ + + ++ I+ F+I P
Sbjct: 723 ----PLFEYTFYNKSVPEDISGGTSILQVR-AKDFDGSSPNNRIVYRIQNGASDKFIIAP 777
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRI 1370
+G + + R + + + YS + + E+ L+ V V V I
Sbjct: 778 ESGIISVARGASLDPD-----LTQPRTLHYSLNVVALDGAPGENQLQA----GVTVNVTI 828
Query: 1371 KDVNDNSPKF 1380
D+N+ +P F
Sbjct: 829 LDINNKNPVF 838
Score = 64.9 bits (151), Expect = 2e-08
Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 10/151 (6%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
N + F L ++G L + ++LD + +Q V + AS+ + T + IE D
Sbjct: 895 NCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMV-EDTASETGPQISTTTITINIE--D 951
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKGAFSID 355
+NDN P+F +Y SI EN NG ++ V+A D D +N TY LD + +D
Sbjct: 952 INDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDAD--KNKTITYTLDGRFEITELIYLD 1009
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
SG L V N+ +D E + L + + A ++
Sbjct: 1010 SNSGDLVVANK--IDHEIYDWLNLTIKATDS 1038
Score = 62.5 bits (145), Expect = 9e-08
Identities = 77/324 (23%), Positives = 128/324 (39%), Gaps = 27/324 (8%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPR-- 136
+ + + I D NDN P FL P + + E TP G + I A G I + R
Sbjct: 1047 VEIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRIS 1106
Query: 137 ---GLTIFKDIRAFD-RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-KVLDYD 191
+I D DK + + ++ D+ + S V D
Sbjct: 1107 SEGKFSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILD 1166
Query: 192 AGDKEFQLVI---MASGKRIHKEILFPEPIHAIDQD---LGVGATLRYELISGNDRKLFS 245
D QL + + H+ HA D D G + ++ GN + F+
Sbjct: 1167 VNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVI-IDISDGNQKNFFA 1225
Query: 246 LDSVNG-SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
L ++ S L L H + L ++A L P + + I + D ND+ P
Sbjct: 1226 LSQISEWSAELRTTTSLRGRHG----NYTLIIRAQDLGTPSHLIEEPLHICVTDFNDHPP 1281
Query: 305 EFEVDFYN--ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKG---AFSIDPRS 358
F +N + + EN G ++++++ATD+D G NG Y+L DP G +F++ P S
Sbjct: 1282 TFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKADPAGHWKSFNLQPVS 1341
Query: 359 GWLTVRNQTVLDREAHSSLRMKVY 382
G L +R ++ +R++ Y
Sbjct: 1342 GILELRLPLDRKKQKVYDIRIEAY 1365
Score = 61.3 bits (142), Expect = 2e-07
Identities = 108/467 (23%), Positives = 192/467 (41%), Gaps = 62/467 (13%)
Query: 945 PIGTTIIKLNALDLDSG-LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIV 1003
P+GT I KL D D L+ +R S+ +D + V+ I+ V +
Sbjct: 67 PVGTLIYKLRGTDPDGDPLSFGVR-----------SQSGSDVIRVEN---ISPTEADVYL 112
Query: 1004 ARSLPPES--EFRLNISALDGGNLNDNI---SVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+ L E+ E+ L ++ DG + N S+ + V+DVND+ P+F + + E
Sbjct: 113 NKELDRETRDEYPLVLTLTDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSITLRE-D 171
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDT-DLPFEISPLTG--VLSVNGELDRETEDK 1115
V+ ++ATD D G + Y +Q DT + F +S G ++ + G LD E +
Sbjct: 172 AAPGVIATLEATDLDEGAYGQVVYQLQEVDTKESLFSVSTAGGKAIVRLVGSLDYEKQTL 231
Query: 1116 YILTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKFYAF-------------DELLEWK 1161
+ L V+A D DV D P+F +L+
Sbjct: 232 HQLKVLAVDRAKQGRVNTGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVT 291
Query: 1162 HPEADE-LSNHNFESVMMIPVYKATIEENAPIGT-TVAKVFANDTDFIGNGNGLILYSLP 1219
+ D ++N S+ + + T + T T+ D + + +G + +
Sbjct: 292 AIDGDRGVNNPILYSLSSNSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQIT 351
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELV 1277
+ + P +T + ++ + D+ DE P F S YYE EI EN VN P+ +
Sbjct: 352 ATEYGGKIKPPPSVTTEVTVI-ITDINDET-----PKFRSGYYECEIAENAPVNTPLTFL 405
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD-TYEVIVR-A 1335
+ E Y ++D I TF + + + +P + + + T+ + V+ +
Sbjct: 406 GSAMPEVY-----------DHDQGINGTFQLYVKGASDVFEITPTKAINEATFMIRVKNS 454
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKY-DVKVVVRIKDVNDNSPKFT 1381
Y + VA+++++ K+ +V VV I D NDN P+FT
Sbjct: 455 TFLDYEKIKTINFTLVAKEIVKHNPKFNEVPVVAHILDRNDNYPEFT 501
Score = 60.9 bits (141), Expect = 3e-07
Identities = 73/326 (22%), Positives = 136/326 (41%), Gaps = 23/326 (7%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVP 135
QIS ++T+ IED+NDN P F Y ++ E + G L + TI T+
Sbjct: 939 QIST-TTITINIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADKNKTITYTLD 997
Query: 136 RGL----TIFKDIRAFDRDKPNTPNSDVHYSI---VSGNDDGHFALESSHKPVLLLRKVL 188
I+ D + D N + +++ + + D G + + V + ++L
Sbjct: 998 GRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSG---IPARFSRVEIFIQIL 1054
Query: 189 DYDAGDKEF----QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
D + + F Q ++++ + +++ I A D D G + Y L + F
Sbjct: 1055 DENDNNPFFLGEPQSLLISEDTPVGRQVAI---IEAKDADSGEFGKITYLLDRISSEGKF 1111
Query: 245 SLDSVNGSLFLEKELDLDAEHN-LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
S+D+ +G L + +LD + +H+ L Q + + A + + +LD+NDN
Sbjct: 1112 SIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILDVNDNH 1171
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKD--QGENGEFTYQLDD--PKGAFSIDPRSG 359
P+ V Y ++I E G ++ A+D D NG+ + D K F++ S
Sbjct: 1172 PQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFALSQISE 1231
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE 385
W T R H + + + A++
Sbjct: 1232 WSAELRTTTSLRGRHGNYTLIIRAQD 1257
Score = 58.0 bits (134), Expect = 2e-06
Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 8/171 (4%)
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDA- 263
+ ++ F P+ +D + T E+ + G+ F+++ G + +D +A
Sbjct: 621 LENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDLSHNFTIEPSTGIIKPRTSIDFEAL 680
Query: 264 EHNLQANT--FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN 321
E +L+ + L V+A P + + I + D+ND+ P FE FYN S+ E++
Sbjct: 681 EGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDHAPLFEYTFYNKSVPEDISG 740
Query: 322 GFSVLQVMATDKD-QGENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQTVLD 370
G S+LQV A D D N Y++ + F I P SG ++V LD
Sbjct: 741 GTSILQVRAKDFDGSSPNNRIVYRIQNGASDKFIIAPESGIISVARGASLD 791
Score = 50.4 bits (115), Expect = 4e-04
Identities = 54/191 (28%), Positives = 90/191 (47%), Gaps = 18/191 (9%)
Query: 218 IHAIDQDLGVGATLRYELIS--GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A D+D+G +RY L + K F+L V+G LE L LD + + + ++
Sbjct: 1307 IIATDEDVGSNGIVRYRLKADPAGHWKSFNLQPVSG--ILELRLPLDRK---KQKVYDIR 1361
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT-DKD 334
++A L P ++ + + + ++ND P+F D + ++ EN P+ ++ T D+D
Sbjct: 1362 IEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTVNFTENKPSEVERQKLPQTVDRD 1421
Query: 335 QGE-NGEFT---YQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE--T 386
+ E +G F Y + + G F + P LTV LDRE + + V A E T
Sbjct: 1422 ELEFDGPFAPICYFIVGGNENGLFKLHPVEHILTVSRP--LDREEKDTHLLLVKATEDCT 1479
Query: 387 NPSVVGTFADS 397
P +F DS
Sbjct: 1480 KPPRNESFFDS 1490
Score = 49.2 bits (112), Expect = 9e-04
Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 8/161 (4%)
Query: 218 IHAIDQDLGVGATL--RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A+D D GV T+ RY +SG+ + + +L G + ++ + + Q + L
Sbjct: 522 VQALDDDSGVFGTMGIRYTHLSGSIQHMLNLHPTTGIISVKTAGGPNWDRE-QISRHYLT 580
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A ++ I + D+NDN P F + Y ++EN + + L+V A D D
Sbjct: 581 VEARDDLGQGNRITVQLIINIEDVNDNPPIFTQNRYEARLLENKLDFENPLKVEARDADL 640
Query: 336 G--ENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREA 373
+N E Y L D F+I+P +G ++ +T +D EA
Sbjct: 641 NGTKNNEIEYSLFGDLSHNFTIEPSTG--IIKPRTSIDFEA 679
Score = 48.8 bits (111), Expect = 0.001
Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 12/174 (6%)
Query: 222 DQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFL---EKELDLDAEHNLQANTFVLQVQ 277
D D G+ T + + +D ++ ++N + F+ + LD E ++ F L +
Sbjct: 414 DHDQGINGTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYE-KIKTINFTLVAK 472
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+NP K + V +LD NDN PEF + Y + + EN G +V V A D D G
Sbjct: 473 EIVKHNP-KFNEVPVVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGV 531
Query: 338 NG----EFTYQLDDPKGAFSIDPRSGWLTVRNQ--TVLDREAHSSLRMKVYAKE 385
G +T+ + ++ P +G ++V+ DRE S + V A++
Sbjct: 532 FGTMGIRYTHLSGSIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARD 585
Score = 47.2 bits (107), Expect = 0.003
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 9/151 (5%)
Query: 237 SGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
SG+D ++ ++ ++L KELD + VL + +L + Q+ + +
Sbjct: 93 SGSDVIRVENISPTEADVYLNKELDRETRDEYP---LVLTLTDGRLGHGNYVTQSLLLL- 148
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAF 352
+ D+NDN P F +I++ E+ G + + ATD D+G G+ YQL D + F
Sbjct: 149 VEDVNDNTPIFTSHQSSITLREDAAPGV-IATLEATDLDEGAYGQVVYQLQEVDTKESLF 207
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
S+ G VR LD E + ++KV A
Sbjct: 208 SVSTAGGKAIVRLVGSLDYEKQTLHQLKVLA 238
Score = 44.0 bits (99), Expect = 0.032
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N ++D + + V V +LD NDN P F+ ++ + + GT +VKA D DL
Sbjct: 1484 NESFFDSSDDTQLKVIVKVLDVNDNAPQFI-HRVFTGGVSTATSFGTTFMEVKAEDADLD 1542
Query: 491 QNGMVLYDLQRTSNLTIT--------SPFKINPNTGTVSVAESPILEGRHALF 535
N + Y L +T+T PF ++ +TG V + P EG F
Sbjct: 1543 DNARMSYFLIGKVQMTLTEGLEDLKRDPFLVDRDTGAVQLNFDP-QEGMKGYF 1594
Score = 42.7 bits (96), Expect = 0.075
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ-LNNP 284
G A + Y ++ GN+ LF L V L + + LD + + +T +L V+A++ P
Sbjct: 1427 GPFAPICYFIVGGNENGLFKLHPVEHILTVSRPLDRE-----EKDTHLLLVKATEDCTKP 1481
Query: 285 LKT---------AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ Q +V +++LD+NDN P+F + + G + ++V A D D
Sbjct: 1482 PRNESFFDSSDDTQLKVIVKVLDVNDNAPQFIHRVFTGGVSTATSFGTTFMEVKAEDADL 1541
Query: 336 GENGEFTYQL 345
+N +Y L
Sbjct: 1542 DDNARMSYFL 1551
Score = 38.7 bits (86), Expect = 1.2
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 986 LEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
L V R E+ H+++ ++ ++ N S D + + + V V V DVND+ P F
Sbjct: 1454 LTVSRPLDREEKDTHLLLVKATEDCTKPPRNESFFDSSD-DTQLKVIVKVLDVNDNAPQF 1512
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+ V A +V A DAD NA ++YF+
Sbjct: 1513 IHRVFTGGVSTATSFGTTFMEVKAEDADLDDNARMSYFL 1551
>UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome shotgun
sequence; n=41; Clupeocephala|Rep: Chromosome 1
SCAF10821, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1151
Score = 130 bits (315), Expect = 2e-28
Identities = 184/735 (25%), Positives = 307/735 (41%), Gaps = 76/735 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + VT+LDANDN PVF S +Y+ S+ N+ + T++ V A D D G N + Y
Sbjct: 222 VVIHVTVLDANDNAPVFSQS-VYKTSLPENSPLDTLVITVSAADADEGVNSEITYGFDHV 280
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
L + F ++ TG V V + E + ++ S A + A + IE+T
Sbjct: 281 --LEDENVFLLDTKTGVVRVNGAIDYEKIPSYEMQIS---AKDGLGLVAYATLIIEIT-D 334
Query: 563 TKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF- 620
N P I + P + NV G+ VG I V D +N+ + ++ VPF
Sbjct: 335 VNDNAPVIHLKSLTNP----IPENVSPGSEVGIINVQDRDSENN--RQVRCSIQQNVPFK 388
Query: 621 ---AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
+++ ++T L R Y+ A E + LS + + V DVND V
Sbjct: 389 LVASIKNYYSLVTT-GQLDRELVSDYNITISATDEGSPPLSSSKSVHLSVADVNDNPPVF 447
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDDIAIAE 734
+ ++S + + N AG+ + + + NGT L A V+ +++
Sbjct: 448 EEQSYSAYVS--ENNRAGSTLCSVSARD-PDWRQNGTVIYSLLAAEVSGAPVSSYVSVNG 504
Query: 735 D-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
D G I + D E+ +++ V+A N + + V++++ D NDNPP + E
Sbjct: 505 DTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNV-SVSVFVSDVNDNPPQILYPAPE 563
Query: 794 G--FIME-NSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
G F+ E K + + + A DAD G NA Y + +F + ++G ++
Sbjct: 564 GNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQSSDPGLFTIGVHSGEIRTQ 623
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI---EENSKVRI 904
D + + L + +D G LS+ + ++I D PE I E+NSK+
Sbjct: 624 RD-ISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISDNLAEVPELKDISYEEKNSKLTS 682
Query: 905 HRETKLNGTAGF--TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
+ L + F T I + +F + P L + I + N D+D
Sbjct: 683 YLIIALVCVSTFFLTFIIIILGVRFC---RRRKPRMLFDGAVTIPGAYLPPNYADVDG-- 737
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDG 1022
G +R +N + Y+ +L + + S++ + ISA D
Sbjct: 738 TGTLRSAYNYDAYLTTGQLDRELV------------------------SDYNITISATDE 773
Query: 1023 GN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
G+ L+ + SV + V DVND+ PVF++ Y+ V E L V A D D+ QN +
Sbjct: 774 GSPPLSSSKSVHLSVADVNDNPPVFEEQSYSAYVRENNRAGSTLCSVSARDPDWRQNGTV 833
Query: 1081 TYFIQPSD-TDLP----FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
Y + ++ + P ++ TGV+ D E + + V+ARDNG
Sbjct: 834 IYSLLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYEQLRSFKVHVMARDNG-SPPLSSNV 892
Query: 1136 XXXXXXXDVNDNSPK 1150
DVNDN P+
Sbjct: 893 SVSVFVSDVNDNPPQ 907
Score = 113 bits (271), Expect = 5e-23
Identities = 118/474 (24%), Positives = 206/474 (43%), Gaps = 42/474 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + + + + D NDN+P F ++ + ++ +A G +A D D+GQN +
Sbjct: 107 ENPLELHRISIHVQDINDNSPQFKEESI-KLEIRESAVKGARFLLGEAHDADIGQNTVQG 165
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPIL-------EGRHALFVEASDQPANPSERR 549
Y LQ+ + FK+N NT + + +L E + L + + +R
Sbjct: 166 YTLQQNDH------FKLNVNTKSSNRKYCELLLDKELDREDKQELQLLLTAVDGGSPQRS 219
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
V I VT + P F + Y+ + N + T V + DA E ++++
Sbjct: 220 ---GTVVIHVT--VLDANDNAPVFSQSVYKTSLPENSPLDTLVITVSAADADEGVNSEIT 274
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y H E+ F ++ ++GV+ V + P Y+ + ++ ++ L + +
Sbjct: 275 YGFDHVLEDENVFLLDTKTGVVRVNGAIDYEKIPSYEMQ-ISAKDGLGLVAYATLIIEIT 333
Query: 668 DVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
DVND V+ LK +PI +V S G+ +G I N+ VR I
Sbjct: 334 DVNDNAPVIHLKSLTNPIPENV---SPGSEVGII---NVQDRDSENNRQVRCSIQQNVPF 387
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+I ++ T LDRE Y +T+ A ++G + V + + D NDNPPV
Sbjct: 388 KLVASIKNYYSLVTTGQLDRELVSDYNITISAT-DEGSPPLSSSKSVHLSVADVNDNPPV 446
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVD 840
FE +Y ++ EN++ G+ + + A D D N +Y+L V+
Sbjct: 447 FEEQSYSAYVSENNRAGSTLCS---VSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVN 503
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+TGV+ + S D E+ +K+ ++ARD G LSS + + + D NDN P+
Sbjct: 504 GDTGVIHAV-RSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQ 556
Score = 79.0 bits (186), Expect = 9e-13
Identities = 110/433 (25%), Positives = 185/433 (42%), Gaps = 54/433 (12%)
Query: 995 NERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWY 1050
N ++ +++ + L E E +L ++A+DGG+ + + + V V D ND+ PVF ++ Y
Sbjct: 184 NRKYCELLLDKELDREDKQELQLLLTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQSVY 243
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELD 1109
++ E ++ V A DAD G N+ +TY F + + F + TGV+ VNG +D
Sbjct: 244 KTSLPENSPLDTLVITVSAADADEGVNSEITYGFDHVLEDENVFLLDTKTGVVRVNGAID 303
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
E Y + + A+D DVNDN+P + L +P + +S
Sbjct: 304 YEKIPSYEMQISAKDG---LGLVAYATLIIEITDVNDNAPVIH----LKSLTNPIPENVS 356
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAK-VFANDTDFIGNGNGLILYSLPQRK--NQQN 1226
+ V +I V E N + ++ + V I N L+ R+ + N
Sbjct: 357 PGS--EVGIINVQDRDSENNRQVRCSIQQNVPFKLVASIKNYYSLVTTGQLDRELVSDYN 414
Query: 1227 L-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+ G P LSS+ + ++VADV D + PVF + Y + EN A L S+
Sbjct: 415 ITISATDEGSPPLSSSKSVHLSVADVND-----NPPVFEEQSYSAYVSENNRAGSTLCSV 469
Query: 1280 NL--TEHYENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + +N + Y +L + + ++ G ++ VRS D E +++V V A
Sbjct: 470 SARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYEQLRSFKVHVMA 529
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF----TNGNRPLVTAI 1391
R S L +V V V + DVNDN P+ GN + +
Sbjct: 530 -RDNGSPPL----------------SSNVSVSVFVSDVNDNPPQILYPAPEGNSFMTELV 572
Query: 1392 PTTAPFGYQVMQL 1404
P A G V ++
Sbjct: 573 PKAAHGGSLVSKV 585
Score = 72.9 bits (171), Expect = 6e-11
Identities = 77/284 (27%), Positives = 121/284 (42%), Gaps = 49/284 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P+ T +I ++A D D G+N +I Y F+ LE + F+++ + G
Sbjct: 247 LPENSPLDTLVITVSAADADEGVNSEITYGFD------------HVLEDENVFLLDTKTG 294
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V V ++ E + + ISA DG L ++ + + DVND+ PV + E
Sbjct: 295 VVRVNGAIDYEKIPSYEMQISAKDGLGLVAYATLIIEITDVNDNAPVIHLKSLTNPIPEN 354
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE-ISPLTGVLSV--NGELDRETED 1114
+G ++ D D N + IQ ++PF+ ++ + S+ G+LDRE
Sbjct: 355 VSPGSEVGIINVQDRDSENNRQVRCSIQ---QNVPFKLVASIKNYYSLVTTGQLDRELVS 411
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y +T+ A D G DVNDN P F +E S
Sbjct: 412 DYNITISATDEG-SPPLSSSKSVHLSVADVNDNPPVF--------------EEQS----- 451
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
Y A + EN G+T+ V A D D+ NG ++YSL
Sbjct: 452 -------YSAYVSENNRAGSTLCSVSARDPDW--RQNGTVIYSL 486
Score = 71.7 bits (168), Expect = 1e-10
Identities = 55/173 (31%), Positives = 80/173 (46%), Gaps = 14/173 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKL-FSLDSVNGS---LFLEKELDLDAEHNLQANTFVLQ 275
A D D+G Y L + KL + S N L L+KELD + + LQ L
Sbjct: 153 AHDADIGQNTVQGYTLQQNDHFKLNVNTKSSNRKYCELLLDKELDREDKQELQ-----LL 207
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A +P ++ + + +LD NDN P F Y S+ EN P V+ V A D D+
Sbjct: 208 LTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQSVYKTSLPENSPLDTLVITVSAADADE 267
Query: 336 GENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G N E TY D + + F +D ++G VR +D E S M++ AK+
Sbjct: 268 GVNSEITYGFDHVLEDENVFLLDTKTG--VVRVNGAIDYEKIPSYEMQISAKD 318
Score = 68.5 bits (160), Expect = 1e-09
Identities = 60/198 (30%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G+T+ ++A D D NG + Y + V Y +N G
Sbjct: 807 VRENNRAGSTLCSVSARDPDWRQNGTVIYSLLAA--------EVSGAPVSSYVSVNGDTG 858
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK------KTW 1049
+ RS E F++++ A D G+ L+ N+SV VFV DVND+ P ++
Sbjct: 859 VIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPAPEGNSF 918
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGEL 1108
V +A + ++ KV A DAD GQNA L+Y +Q SD L F I +G + ++
Sbjct: 919 MTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQSSDPGL-FTIGVHSGEIRTQRDI 977
Query: 1109 DRETEDKYILTVVARDNG 1126
K L V +DNG
Sbjct: 978 SESDSMKQNLIVAVKDNG 995
Score = 61.3 bits (142), Expect = 2e-07
Identities = 61/235 (25%), Positives = 105/235 (44%), Gaps = 10/235 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +V +++ D NDN PVF + Y ++ N + G+ + V A DPD QNG V+Y
Sbjct: 778 LSSSKSVHLSVADVNDNPPVFEEQS-YSAYVRENNRAGSTLCSVSARDPDWRQNGTVIYS 836
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAV 554
L S ++S +N +TG + S E + + V A D + P S++V
Sbjct: 837 LLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSV 896
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLLH 612
+V P+ E + G G+ V ++ DA QN +SY ++
Sbjct: 897 FVSDVNDNPPQILYPAPEGNSFMTELVPKAAHG-GSLVSKVIAVDADSGQNAWLSYHIVQ 955
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
+ G+ F + SG I D+S + M VA+++N S+ +++++
Sbjct: 956 SSDPGL-FTIGVHSGEIRTQRDISE-SDSMKQNLIVAVKDNGQPSLSATCSMYLL 1008
Score = 58.4 bits (135), Expect = 1e-06
Identities = 83/351 (23%), Positives = 147/351 (41%), Gaps = 26/351 (7%)
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTG 714
LS + + V DVND V + ++S +V+EN+ AG+ + + + NGT
Sbjct: 778 LSSSKSVHLSVADVNDNPPVFEEQSYSA---YVRENNRAGSTLCSVSARD-PDWRQNGTV 833
Query: 715 NVRFLIANQQD--VTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
L A V+ +++ D G I + D E+ +++ V+A N + +
Sbjct: 834 IYSLLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNV- 892
Query: 772 QVTIYIEDENDNPPVFEHATYEG--FIME-NSKIGTEIKMDNIIKATDADEGTNALFMYT 828
V++++ D NDNPP + EG F+ E K + + + A DAD G NA Y
Sbjct: 893 SVSVFVSDVNDNPPQILYPAPEGNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYH 952
Query: 829 LF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
+ +F + ++G ++ D + + L + +D G LS+ + ++I D
Sbjct: 953 IVQSSDPGLFTIGVHSGEIRTQRD-ISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISD 1011
Query: 886 ENDNKPEFNQI---EENSKVRIHRETKLNGTAGF--TIIEVKPKNKFALDVDQLGPLFLI 940
PE I E+NSK+ + L + F T I + +F + P L
Sbjct: 1012 NLAEVPELKDISYEEKNSKLTSYLIIALVCVSTFFLTFIIIILGVRFC---RRRKPRMLF 1068
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY 991
+ I + N D+D G +R +N + Y+ ++D V Y
Sbjct: 1069 DGAVTIPGAYLPPNYADVDG--TGTLRSAYNYDAYLTTGSRTSDFKFVTSY 1117
Score = 46.8 bits (106), Expect = 0.005
Identities = 100/373 (26%), Positives = 150/373 (40%), Gaps = 63/373 (16%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEA--QYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ + V+D+ND+ P FK+ + E+ + R +LG +A DAD GQN Y +Q +D
Sbjct: 115 ISIHVQDINDNSPQFKEESIKLEIRESAVKGARFLLG--EAHDADIGQNTVQGYTLQQND 172
Query: 1089 TDLPFEISPLTG-----VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
++ + L ++ ELDRE + + L + A D G D
Sbjct: 173 -HFKLNVNTKSSNRKYCELLLDKELDREDKQELQLLLTAVDGG-SPQRSGTVVIHVTVLD 230
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
NDN+P F +SV YK ++ EN+P+ T V V A D
Sbjct: 231 ANDNAPVF---------------------SQSV-----YKTSLPENSPLDTLVITVSAAD 264
Query: 1204 TDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA----DVPD-EVEMSDKP-VF 1257
D N I Y +N+ L + T ++ V A +P E+++S K +
Sbjct: 265 AD--EGVNSEITYGFDHVLEDENVFLLD-TKTGVVRVNGAIDYEKIPSYEMQISAKDGLG 321
Query: 1258 ISRYYELEIE---ENVNAPV-ELVSL-NLTEHYENFKMRYYILNENDTDI---RRTFVID 1309
+ Y L IE N NAPV L SL N + I+N D D R+
Sbjct: 322 LVAYATLIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINVQDRDSENNRQVRCSI 381
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL--PHMIYPVAEDVLEGMTKYDVKVV 1367
+N LV S +K+ Y ++ + REL + I A D V
Sbjct: 382 QQNVPFKLVAS----IKNYYSLVTTGQ---LDRELVSDYNITISATDEGSPPLSSSKSVH 434
Query: 1368 VRIKDVNDNSPKF 1380
+ + DVNDN P F
Sbjct: 435 LSVADVNDNPPVF 447
Score = 45.6 bits (103), Expect = 0.011
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
N K SL+ G L +++ +D +A +A+ VL+ Q L NPL+ R+ I + D
Sbjct: 66 NSVKYCSLNLNTGELIVQERIDREALCEKKASC-VLK-QELVLENPLELH--RISIHVQD 121
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+NDN P+F+ + + I E+ G L A D D G+N Y L
Sbjct: 122 INDNSPQFKEESIKLEIRESAVKGARFLLGEAHDADIGQNTVQGYTL 168
Score = 45.6 bits (103), Expect = 0.011
Identities = 90/371 (24%), Positives = 149/371 (40%), Gaps = 33/371 (8%)
Query: 47 DSPQNVVKFRLGCDFDEGDDL-VRIGA--GLNQISAYLSVTVYIEDVNDNVPIF-LDTPY 102
D+ VV+ D+++ ++I A GL + AY ++ + I DVNDN P+ L +
Sbjct: 290 DTKTGVVRVNGAIDYEKIPSYEMQISAKDGLGLV-AYATLIIEITDVNDNAPVIHLKSLT 348
Query: 103 HVTVDELTPTGEKAFIFLIAPIGPS-----LTIPLTVPRGLTI-FKDIRAFDRDKPNTPN 156
+ + ++P E I + + +I VP L K+ +
Sbjct: 349 NPIPENVSPGSEVGIINVQDRDSENNRQVRCSIQQNVPFKLVASIKNYYSLVTTGQLDRE 408
Query: 157 SDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP 215
Y+I +S D+G L SS L + V D +E S L
Sbjct: 409 LVSDYNITISATDEGSPPLSSSKSVHLSVADVNDNPPVFEEQSYSAYVSENNRAGSTLCS 468
Query: 216 EPIHAIDQDLGVGATLRYELISG--NDRKLFSLDSVNGSL-FLEKELDLDAEHNLQANTF 272
+ A D D T+ Y L++ + + S SVNG + D E Q +F
Sbjct: 469 --VSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYE---QLRSF 523
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSVL- 326
+ V A +P ++ V + + D+NDN P+ E + + +V +G S++
Sbjct: 524 KVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPAPEGNSFMTELVPKAAHGGSLVS 583
Query: 327 QVMATDKDQGENGEFTY---QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+V+A D D G+N +Y Q DP G F+I SG +R Q + + V
Sbjct: 584 KVIAVDADSGQNAWLSYHIVQSSDP-GLFTIGVHSG--EIRTQRDISESDSMKQNLIVAV 640
Query: 384 KET-NPSVVGT 393
K+ PS+ T
Sbjct: 641 KDNGQPSLSAT 651
Score = 44.0 bits (99), Expect = 0.032
Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 218 IHAIDQDLGVGATLRYELISG--NDRKLFSLDSVNGSL-FLEKELDLDAEHNLQANTFVL 274
+ A D D T+ Y L++ + + S SVNG + D E Q +F +
Sbjct: 820 VSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVNGDTGVIHAVRSFDYE---QLRSFKV 876
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSVL-QV 328
V A +P ++ V + + D+NDN P+ E + + +V +G S++ +V
Sbjct: 877 HVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPAPEGNSFMTELVPKAAHGGSLVSKV 936
Query: 329 MATDKDQGENGEFTY---QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+A D D G+N +Y Q DP G F+I SG +R Q + + V K+
Sbjct: 937 IAVDADSGQNAWLSYHIVQSSDP-GLFTIGVHSG--EIRTQRDISESDSMKQNLIVAVKD 993
Query: 386 T-NPSVVGT 393
PS+ T
Sbjct: 994 NGQPSLSAT 1002
Score = 43.6 bits (98), Expect = 0.043
Identities = 22/72 (30%), Positives = 36/72 (50%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ + A+ +P ++ V + + D+NDN P FE Y+ + EN G ++ V A D
Sbjct: 766 ITISATDEGSPPLSSSKSVHLSVADVNDNPPVFEEQSYSAYVRENNRAGSTLCSVSARDP 825
Query: 334 DQGENGEFTYQL 345
D +NG Y L
Sbjct: 826 DWRQNGTVIYSL 837
Score = 38.3 bits (85), Expect = 1.6
Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 14/115 (12%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP-----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
L S V+V V + D NDN P + P S + E K+ A G+++ KV AVD D GQN
Sbjct: 537 LSSNVSVSVFVSDVNDNPPQILYPAPEGNSFMTELVPKA-AHGGSLVSKVIAVDADSGQN 595
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTV----SVAESPILEGRHALFVEASDQPA 543
+ Y + ++S+ + F I ++G + ++ES ++ + V+ + QP+
Sbjct: 596 AWLSYHIVQSSDPGL---FTIGVHSGEIRTQRDISESDSMKQNLIVAVKDNGQPS 647
Score = 37.1 bits (82), Expect = 3.7
Identities = 37/169 (21%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 218 IHAIDQDLGVGATLRYELISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D GV + + Y D +F LD+ G + + +D + + ++ +Q+
Sbjct: 260 VSAADADEGVNSEITYGFDHVLEDENVFLLDTKTGVVRVNGAIDYE-----KIPSYEMQI 314
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A + A A + IE+ D+NDN P + I EN+ G V + D+D
Sbjct: 315 SAK--DGLGLVAYATLIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINVQDRDSE 372
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + + + + ++ LDRE S + + A +
Sbjct: 373 NNRQVRCSIQQNVPFKLVASIKNYYSLVTTGQLDRELVSDYNITISATD 421
>UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein; n=3;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 3267
Score = 130 bits (314), Expect = 3e-28
Identities = 133/474 (28%), Positives = 218/474 (45%), Gaps = 38/474 (8%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T +++++ +E+ + + ++ +LD NDN+P FV ++ + + +VG ++ V A D
Sbjct: 1488 TASDSLKEPNERKNASIIAQMIVLDINDNSPTFVSMDIA--CVPEDTEVGLLVHHVMAKD 1545
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPAN 544
D G+NG V Y + + S F + +TG + + S E +H L V+A D
Sbjct: 1546 KDEGRNGHVTYSVSSGNE---KSYFHME-STGHLFLNSSLDYESQHVHILIVQARDNGVP 1601
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ- 603
+L V ++V + P P F Y V N G + Q+ D +
Sbjct: 1602 SLSSTQTLTVKVLDVN-----DHP--PVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEV 1654
Query: 604 -NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
+ VSY LL G + F + +G I+ L R + + A E++ +++
Sbjct: 1655 NSAVSYSLLPGPGYEL-FRINSHTGHISTSVRLDREIQSTFTLRVQA--EDSGTPSLSST 1711
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIA 721
T + V DE + + + + EN A I H +S NG G +++ I
Sbjct: 1712 TTVLCSVLDENDNAPQFSQPDLHIVIPENLAPGVI----HIVQASDIDNGLNGTIQYSIE 1767
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDE 780
+ + + D A G I T +PLDRE+R Y + + A + +S + + +T+ DE
Sbjct: 1768 DLECFSID---AVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITL--TDE 1822
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P+F +Y I E +GTEI ++I A D DEG N + ++L E F VD
Sbjct: 1823 NDNSPLFARKSYRASISEGLPVGTEIL--HLI-AWDPDEGANGVVTFSLEEENSGNFHVD 1879
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKP 891
+TGV+K + LDRE + + VA D G SS A + I + D NDN P
Sbjct: 1880 GSTGVIK-LTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTP 1932
Score = 118 bits (285), Expect = 9e-25
Identities = 142/549 (25%), Positives = 236/549 (42%), Gaps = 44/549 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ ++T+LD NDN PVF S Y + NA + T + ++ A D DLG NG V+Y + R
Sbjct: 219 LQAQITVLDENDNQPVFNQSE-YHAVILENATLMTPVCQIFATDADLGSNGQVIYGINRR 277
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F I ++G +SV + E + L V A D P +++ + V
Sbjct: 278 QS-DPNEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSGIQPESSNTFVSIKVLNVN 336
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ GAP V G V +I V+D + D+L +G+ F
Sbjct: 337 DNPPNISVLFLNEAGAPE---VSEGAGFEDYVARIAVSDPDLGDVKKIDVLLQGGDGM-F 392
Query: 621 AVEERSG---VITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
++ V+ V L R + +Y+ A LS V + V DVND V
Sbjct: 393 SLRSMDDFLYVLCVDGPLDREIKDLYELTVTASDYGCPPLSSVITFQIQVTDVNDNPPVF 452
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + I ++ G A+ ++ T+ G + + ++ ++Q +I G
Sbjct: 453 HQTIYEESID--EDVRVGTAVFRVKATDKD--LGGDSEIIYSIVQSEQKCPFNIDPTL-G 507
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T LD E+ R V+A + G S + V I++ED NDN P+F Y +
Sbjct: 508 VITTAAALDHERERELRFLVVAS-DGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATV 566
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM---FDVDENTGVVKFIGDSL 853
E++ +GT I I A A+ G+ F+Y F GK++ F ++ TG + + +
Sbjct: 567 KEHTAVGTCILQVTAIDADGAEFGSVQYFLYDGF-SGKDVHPFFHINSVTGNI-CVSQDI 624
Query: 854 DREKKIM-YKLSLVARD-------TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
D E ++ + L + A D G SS+ + I I D NDN P FN + + V +H
Sbjct: 625 DYEAGLLTFDLLIKAEDQVSLSFVKDGFSSQTFVHIGIEDVNDNAPVFNPGKYVTSVSVH 684
Query: 906 RE--TKL---------NGTAGFTIIEVKPKNKFAL-DVDQ-LGPLFLIPENIPIGTTIIK 952
+ T+L G G E++P + L +DQ G ++L + + ++ +K
Sbjct: 685 AQPGTELLNVYASDQDAGNYGKITYELQPGDSATLFTMDQSTGSVYLSSSLMQLRSSSVK 744
Query: 953 LNALDLDSG 961
L+ D G
Sbjct: 745 LSVSARDGG 753
Score = 117 bits (282), Expect = 2e-24
Identities = 124/493 (25%), Positives = 216/493 (43%), Gaps = 42/493 (8%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y L S + ++ + D NDN PVF +YE S+ + +VGT + +VKA D DLG +
Sbjct: 426 DYGCPPLSSVITFQIQVTDVNDNPPVF-HQTIYEESIDEDVRVGTAVFRVKATDKDLGGD 484
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYS 551
++Y + ++ PF I+P G ++ A + E L F+ + +PS S
Sbjct: 485 SEIIYSIVQSEQ---KCPFNIDPTLGVITTAAALDHERERELRFLVVASDGGSPS--LSS 539
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYD 609
A V I V NKP P Y V + +GT + Q+ DA E V Y
Sbjct: 540 TATVIIHV-EDVNDNKPIFPQKF---YNATVKEHTAVGTCILQVTAIDADGAEFGSVQYF 595
Query: 610 LLHGY--EEGVP-FAVEERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIV-----T 660
L G+ ++ P F + +G I V D+ Y + F+ + ++ +LS V +
Sbjct: 596 LYDGFSGKDVHPFFHINSVTGNICVSQDID-YEAGLLTFDLLIKAEDQVSLSFVKDGFSS 654
Query: 661 NATVH--VVDVNDERGVLLKGAH-SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
VH + DVND V G + + + H + G + ++ ++ + GN G +
Sbjct: 655 QTFVHIGIEDVNDNAPVFNPGKYVTSVSVHAQ---PGTELLNVYASDQDA--GN-YGKIT 708
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ + T G+++ L + + +++V A + G +S A +T+ I
Sbjct: 709 YELQPGDSATLFTMDQSTGSVYLSSSLMQLRSSSVKLSVSAR-DGGGMSAAYPANITVNI 767
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF 837
+ P +F+ A Y I E++ +G+ + +++A + G+ + F
Sbjct: 768 LQSDQPPALFQKAQYTFSISEDAPVGSSV---GLVQAITPANSVEVVSYVISSGDPQGFF 824
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEFNQ 895
+D TG++ LD E I Y + + TG L S A++ + I D NDN P F +
Sbjct: 825 SIDSQTGIIN-TAQPLDHE-SISYVILNIQFHTGTLPIHSSAQVNVSITDINDNPPVFQK 882
Query: 896 IEENSKVRIHRET 908
E+ + I R T
Sbjct: 883 TSEH--ITISRTT 893
Score = 112 bits (269), Expect = 8e-23
Identities = 168/710 (23%), Positives = 285/710 (40%), Gaps = 91/710 (12%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ V +TL D NDN PVF S Y ++ T + +V A D D G NG + Y +
Sbjct: 2121 AYARVAITLQDINDNAPVFKQS-YYRTAVWEGQIHNTYVMQVLATDSDSGVNGQISYFIM 2179
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
++ + T +V + I+ + L ++A D P ++ V ++V
Sbjct: 2180 DGNHNNAFVIDSVRGILATNAVLDREIVSS-YKLIIQAKDMGKAPLTGTCTVRVQVVDVN 2238
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P IP + N+ +G V ++ ND +Y L+ + F
Sbjct: 2239 ----DNSPTIPSMEAVT----IAENLPLGYIVTRVIANDVDLSPSATYRLIEKDDTSRSF 2290
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
A++ +G+IT L + +Y + A ++ ++ V+DVND V + +
Sbjct: 2291 AIDLYTGIITTTKILDYEEQSVYTLKVQA--SDSVHQTEAELSIQVLDVNDNSPVFSQES 2348
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
+ ++ + A + + T+ S NG + R L + D ++G++FT
Sbjct: 2349 YQVLLS--ERTLADTFVVSVLATDKDS-GKNGRVSYRLLSSPVGGFYID---PDNGSVFT 2402
Query: 741 QKPLDREKR-DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
KPL+ +V R+ V A + G + + V I + D NDN P F +Y+ I E+
Sbjct: 2403 NKPLNYVANGNVLRLLVEAR-DSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPED 2461
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+G+ + TL E K+ D ENT + I D +
Sbjct: 2462 VSVGSTL--------------------ITLLAEDKDYSD--ENTHLEYLIISGNDERRFC 2499
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTII 919
+ +S+ A + +++ D D + + S + +N T++
Sbjct: 2500 LEVVSIQAEPHSRTVGQ----LVLCDTLDRETT----DAYSLTVTVTDRGINPLNSSTVV 2551
Query: 920 EVKPKNKFALDVDQLGPLFLIPE-------NIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
VK LD++ P F PE N P+G +++++A D D G NG I Y
Sbjct: 2552 SVK-----VLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYDPDLGANGTITYNI-- 2604
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNIS--ALDGGNLNDN-I 1029
+S ++ K ++ G + V +L E + +L ++ A D G +D +
Sbjct: 2605 --------ISGNS---KGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKV 2653
Query: 1030 S---VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQ 1085
S V + V D ND+ P F YN +V E + V A D D G L+Y +
Sbjct: 2654 SFAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVT 2713
Query: 1086 PS----DTDLP-----FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
P D+ P F I PLTG + D E + + V ARD G
Sbjct: 2714 PCFVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKG 2763
Score = 109 bits (263), Expect = 4e-22
Identities = 125/482 (25%), Positives = 216/482 (44%), Gaps = 34/482 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVF--VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+L + + +T+ D NDN P F +PS E ++ + V +V+ + A D D G+NG V
Sbjct: 1178 RLNTTTTIHITVTDVNDNRPQFTHMPSTK-ELNVWAVIPVNSVVISMFAKDLDAGENGTV 1236
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLA 553
+ + T N F I+ +G V V S + R+ L V A+D P E A
Sbjct: 1237 KFSM--TDNQL--GHFSIDSLSGDVKVTSQFSSNPQMRYTLRVVATDNGLFPLEET---A 1289
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
VV I+V + + +F + F V +VG+GT +G + V++A ++ Y ++ G
Sbjct: 1290 VVHIQVYVLDQQKE----NFQSSFQHFTVLEDVGLGTIIGSLGVSNA-PDTELRYSIVEG 1344
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+ F ++ SG + V L Y F V + ++ A V ++DVND
Sbjct: 1345 -NGSLQFGIKSSSGELYVAQHLD-YEVTQRYFLVVRAEAFPTFNVTVFAAVSILDVNDHN 1402
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ +IF V E+ + + +F+ + + L + + + +
Sbjct: 1403 PWFPSNGNI-VIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAIEGLPLH 1461
Query: 734 ED---GTIFTQKPLDREKRD--VYRMTVIAEFNK-GVISGAGIYQVTIYIEDENDNPPVF 787
D G + T LDRE+ + ++R+T + A I I + D NDN P F
Sbjct: 1462 IDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNERKNASIIAQMIVL-DINDNSPTF 1520
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ E++++G + + + A D DEG N Y++ ++ + E+TG +
Sbjct: 1521 VSMDI-ACVPEDTEVGLLV---HHVMAKDKDEGRNGHVTYSVSSGNEKSYFHMESTGHL- 1575
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
F+ SLD E + ++ L + ARD G LSS L + + D ND+ P F Q N+ V +
Sbjct: 1576 FLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVLDVNDHPPVFQQHIYNTTVIEN 1635
Query: 906 RE 907
R+
Sbjct: 1636 RD 1637
Score = 109 bits (261), Expect = 8e-22
Identities = 127/458 (27%), Positives = 197/458 (43%), Gaps = 32/458 (6%)
Query: 447 VTLLDANDNNPVFVPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY-DLQRTSN 504
V++LD ND+NP F + N+ F + + GTV+ A D D + LY L +
Sbjct: 1393 VSILDVNDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPS 1452
Query: 505 LTITS-PFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEVTR 561
I P I+P+TG V+ E + V ASD P+ER+ + +++ +
Sbjct: 1453 PAIEGLPLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNERK-NASIIAQMIVL 1511
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
N P A V + +G V + D E + V+Y + G E+
Sbjct: 1512 DINDNSPTFVSMDIA----CVPEDTEVGLLVHHVMAKDKDEGRNGHVTYSVSSGNEKSY- 1566
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVNDERGVLL 677
F +E +G + + L Y V ++N +LS TV V+DVND V
Sbjct: 1567 FHMES-TGHLFLNSSLD-YESQHVHILIVQARDNGVPSLSSTQTLTVKVLDVNDHPPVFQ 1624
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ ++ + ++ G I Q+ ++ S + V + + + G
Sbjct: 1625 QHIYNTTV--IENRDPGEIIVQVTTVDLDSEVNSA---VSYSLLPGPGYELFRINSHTGH 1679
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I T LDRE + + + V AE + G S + V + DENDN P F I
Sbjct: 1680 ISTSVRLDREIQSTFTLRVQAE-DSGTPSLSSTTTVLCSVLDENDNAPQFSQPDLHIVIP 1738
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN G + +I++A+D D G N Y++ E E F +D TG+++ LDRE+
Sbjct: 1739 ENLAPG----VIHIVQASDIDNGLNGTIQYSI--EDLECFSIDAVTGMIRTTRP-LDREE 1791
Query: 858 KIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ Y L + A D G LSS A L I + DENDN P F
Sbjct: 1792 RSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLF 1829
Score = 102 bits (244), Expect = 9e-20
Identities = 124/473 (26%), Positives = 200/473 (42%), Gaps = 74/473 (15%)
Query: 929 LDVDQLGPLFL------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
LD++ P F+ +PE+ +G + + A D D G NG + Y +S
Sbjct: 1511 LDINDNSPTFVSMDIACVPEDTEVGLLVHHVMAKDKDEGRNGHVTYSVSSG--------- 1561
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGG--NLNDNISVRVFVKDV 1038
K YF + E GH+ + SL ES+ L + A D G +L+ ++ V V DV
Sbjct: 1562 ----NEKSYFHM-ESTGHLFLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVLDV 1616
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
NDH PVF++ YN V E + ++ +V D D N+ ++Y + P F I+
Sbjct: 1617 NDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGPGYELFRINSH 1676
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
TG +S + LDRE + + L V A D+G D NDN+P+F
Sbjct: 1677 TGHISTSVRLDREIQSTFTLRVQAEDSG-TPSLSSTTTVLCSVLDENDNAPQF------- 1728
Query: 1159 EWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
P+ + N + +I + +A+ +N GT + + I G+I +
Sbjct: 1729 --SQPDLHIVIPENL-APGVIHIVQASDIDNGLNGTIQYSIEDLECFSIDAVTGMIRTTR 1785
Query: 1219 P----QRKNQQNL------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
P +R N L G P LSS+A+L +T+ D E + P+F + Y I E
Sbjct: 1786 PLDREERSNYSLLITAADHGHPPLSSSALLHITLTD-----ENDNSPLFARKSYRASISE 1840
Query: 1269 NVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
+ E++ L + E N + + + EN + F +D G + L + DRE +
Sbjct: 1841 GLPVGTEILHLIAWDPDEGANGVVTFSLEEENSGN----FHVDGSTGVIKLTKPLDRETR 1896
Query: 1327 DTYEVIVRAERQKYSRELPHMIYPVAED-VLEGMTKYDVKVVVRIKDVNDNSP 1378
H+ VA D EG V ++++D+NDN+P
Sbjct: 1897 S-----------------QHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTP 1932
Score = 100 bits (239), Expect = 4e-19
Identities = 111/459 (24%), Positives = 190/459 (41%), Gaps = 32/459 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + + D NDN P V + N + I KV A DPDLG NG V++ L
Sbjct: 1916 SIATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLP 1975
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTI 557
L F+++ +G V + ++P+ + G L + A D PS L ++ +
Sbjct: 1976 EEDEL-----FQVD-GSGAVRL-KAPLSNEVSGTKLLRIRAEDL-GRPSLTSSCLLLIQL 2027
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND-AFEQNDVSYDLLHGYEE 616
++ + F YE V N G+ V + +D ++ + Y++ G E
Sbjct: 2028 -------NDEEPLLQFTEELYEVAVPENSKTGSWVANVVAHDQTSDEGMIKYNIFSG-NE 2079
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F + +G ITV D + V L EN + + + + D+ND V
Sbjct: 2080 NEAFIINPVTGDITVNDQRLLDFEVQRKVQLVVLAENGHQTAYARVAITLQDINDNAPVF 2139
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + ++ + ++ + Q+ T+ S G + + I + + + G
Sbjct: 2140 KQSYYRTAVWEGQIHN--TYVMQVLATDSDS---GVNGQISYFIMDGNHNNAFVIDSVRG 2194
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ T LDRE Y++ + A+ + G G V + + D NDN P + I
Sbjct: 2195 ILATNAVLDREIVSSYKLIIQAK-DMGKAPLTGTCTVRVQVVDVNDNSPTIP-SMEAVTI 2252
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN +G + + A D D +A + + F +D TG++ LD E
Sbjct: 2253 AENLPLGYIVTR---VIANDVDLSPSATYRLIEKDDTSRSFAIDLYTGIIT-TTKILDYE 2308
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
++ +Y L + A D+ +EAEL I + D NDN P F+Q
Sbjct: 2309 EQSVYTLKVQASDSVH-QTEAELSIQVLDVNDNSPVFSQ 2346
Score = 98.7 bits (235), Expect = 1e-18
Identities = 122/470 (25%), Positives = 204/470 (43%), Gaps = 47/470 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD-PDLGQNGMVLYDLQR 501
V+++V +LD N S+ F++ + +GT+IG + + PD + Y +
Sbjct: 1291 VHIQVYVLDQQKEN---FQSSFQHFTVLEDVGLGTIIGSLGVSNAPDTE----LRYSIVE 1343
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ + F I ++G + VA+ E F+ + A P+ A V+I
Sbjct: 1344 GNG---SLQFGIKSSSGELYVAQHLDYEVTQRYFLVVRAE-AFPTFNVTVFAAVSI---L 1396
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGYE--- 615
+ P P G F V +V GT V D + +++ Y L
Sbjct: 1397 DVNDHNPWFPS-NGNIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAI 1455
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ------ENANLSIVTNATVHVVDV 669
EG+P ++ +GV+T L R F A E N SI+ A + V+D+
Sbjct: 1456 EGLPLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNERKNASII--AQMIVLDI 1513
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTD 728
ND + S I V E++ +G + H M+ G G+V + +++ + +
Sbjct: 1514 NDNSPTFV----SMDIACVPEDTE---VGLLVHHVMAKDKDEGRNGHVTYSVSSGNEKSY 1566
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ G +F LD E + V+ + V A N GV S + +T+ + D ND+PPVF+
Sbjct: 1567 -FHMESTGHLFLNSSLDYESQHVHILIVQARDN-GVPSLSSTQTLTVKVLDVNDHPPVFQ 1624
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
Y ++EN G I + D D N+ Y+L G G E+F ++ +TG +
Sbjct: 1625 QHIYNTTVIENRDPGEIIVQ---VTTVDLDSEVNSAVSYSLLPGPGYELFRINSHTGHIS 1681
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LDRE + + L + A D+G LSS ++ + DENDN P+F+Q
Sbjct: 1682 -TSVRLDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQ 1730
Score = 98.7 bits (235), Expect = 1e-18
Identities = 91/316 (28%), Positives = 144/316 (45%), Gaps = 20/316 (6%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP---IGPSLTIPLTV 134
S+ +VT+ +ED+NDN P + P V+V + + + A +G + T+ +
Sbjct: 1915 SSIATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRL 1974
Query: 135 PRGLTIFK-DIRAFDRDKPNTPN--SDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
P +F+ D R K N S + D G +L SS LLL ++ D +
Sbjct: 1975 PEEDELFQVDGSGAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSS---CLLLIQLNDEE 2031
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
+ + + + K + + A DQ G ++Y + SGN+ + F ++ V G
Sbjct: 2032 PLLQFTEELYEVAVPENSKTGSWVANVVAHDQTSDEGM-IKYNIFSGNENEAFIINPVTG 2090
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ + + LD E + VL Q TA ARV I L D+NDN P F+ +Y
Sbjct: 2091 DITVNDQRLLDFEVQRKVQLVVLAENGHQ------TAYARVAITLQDINDNAPVFKQSYY 2144
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVL 369
++ E + V+QV+ATD D G NG+ +Y + D AF ID G L VL
Sbjct: 2145 RTAVWEGQIHNTYVMQVLATDSDSGVNGQISYFIMDGNHNNAFVIDSVRGILA--TNAVL 2202
Query: 370 DREAHSSLRMKVYAKE 385
DRE SS ++ + AK+
Sbjct: 2203 DREIVSSYKLIIQAKD 2218
Score = 96.3 bits (229), Expect = 6e-18
Identities = 109/478 (22%), Positives = 211/478 (44%), Gaps = 36/478 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++ + + S V + + D NDN PVF P Y S+ +A+ GT + V A D D G
Sbjct: 644 SLSFVKDGFSSQTFVHIGIEDVNDNAPVFNPGK-YVTSVSVHAQPGTELLNVYASDQDAG 702
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
G + Y+LQ + T+ F ++ +TG+V ++ S + ++ + S + Y
Sbjct: 703 NYGKITYELQPGDSATL---FTMDQSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSAAY 759
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR-VNDAFEQNDVSYD 609
A +T+ + + + P + F A Y F + + +G+SVG ++ + A VSY
Sbjct: 760 P-ANITVNILQSDQ--PPAL--FQKAQYTFSISEDAPVGSSVGLVQAITPANSVEVVSYV 814
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHV-- 666
+ G +G F+++ ++G+I L + + + +Q L I ++A V+V
Sbjct: 815 ISSGDPQGF-FSIDSQTGIINTAQPL---DHESISYVILNIQFHTGTLPIHSSAQVNVSI 870
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D+ND V K + H+ + +F + G + +++ + +
Sbjct: 871 TDINDNPPVFQKTSE-----HITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSHL 925
Query: 727 TDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN--DN 783
I + GT+ + R+ Y +++IAE ++G S + + I ++ D+
Sbjct: 926 ---FTIHPNLGTLMLNGDVSRDSSSRYELSIIAE-DEGHPSLSSTLGLVIEMDSSASVDD 981
Query: 784 PPVFEHATYEGFIMENSKIGTEI----KMDNIIKATDADEGTNALFMYTLFG-EGKEMFD 838
FE Y+ I E++ T + N + T ++ Y+L G F
Sbjct: 982 TLAFETLVYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFR 1041
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ TG + F+ SLD E + Y+ + A+ + + A +++M+ DENDN P F++
Sbjct: 1042 IHPETGWM-FVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSR 1098
Score = 91.1 bits (216), Expect = 2e-16
Identities = 88/316 (27%), Positives = 143/316 (45%), Gaps = 30/316 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE----KAFIFLIAPIGPSL 128
G+ +S+ ++TV + DVND+ P+F Y+ TV E GE + L + + ++
Sbjct: 1599 GVPSLSSTQTLTVKVLDVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAV 1658
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-----VSGNDDGHFALESSHKPVLL 183
+ L G +F+ I + + D V D G +L S+ +
Sbjct: 1659 SYSLLPGPGYELFR-INSHTGHISTSVRLDREIQSTFTLRVQAEDSGTPSLSST---TTV 1714
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGND 240
L VLD + +F + + E L P IH + D D G+ T++Y + D
Sbjct: 1715 LCSVLDENDNAPQFSQPDLHI---VIPENLAPGVIHIVQASDIDNGLNGTIQYSI---ED 1768
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
+ FS+D+V G + + LD + N + L + A+ +P ++ A + I L D N
Sbjct: 1769 LECFSIDAVTGMIRTTRPLDREERSN-----YSLLITAADHGHPPLSSSALLHITLTDEN 1823
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-KGAFSIDPRSG 359
DN P F Y SI E LP G +L ++A D D+G NG T+ L++ G F +D +G
Sbjct: 1824 DNSPLFARKSYRASISEGLPVGTEILHLIAWDPDEGANGVVTFSLEEENSGNFHVDGSTG 1883
Query: 360 WLTVRNQTVLDREAHS 375
++ LDRE S
Sbjct: 1884 --VIKLTKPLDRETRS 1897
Score = 90.6 bits (215), Expect = 3e-16
Identities = 105/415 (25%), Positives = 179/415 (43%), Gaps = 52/415 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+IPEN+ G I + A D+D+GLNG I+Y S + LE F I+
Sbjct: 1736 VIPENLAPGVIHI-VQASDIDNGLNGTIQY-------------SIEDLEC---FSIDAVT 1778
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + R L E S + L I+A D G+ L+ + + + + D ND+ P+F + Y ++
Sbjct: 1779 GMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLFARKSYRASI 1838
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + + A D D G N +T+ ++ ++ F + TGV+ + LDRET
Sbjct: 1839 SEGLPVGTEILHLIAWDPDEGANGVVTFSLEEENSG-NFHVDGSTGVIKLTKPLDRETRS 1897
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+++ VA D D+NDN+P K P +S+ N
Sbjct: 1898 QHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACV--------KEPMRVSVSSVNTR 1949
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP----------QRKNQ 1224
I A + GT V ++ D F +G+G + P R
Sbjct: 1950 PNRPIAKVTAQDPDLGDNGTVVFRLPEEDELFQVDGSGAVRLKAPLSNEVSGTKLLRIRA 2009
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
++LG PSL+S+ +L++ + D ++ F YE+ + EN + ++ +
Sbjct: 2010 EDLGRPSLTSSCLLLIQLNDEEPLLQ------FTEELYEVAVPENSKTGSWVANVVAHDQ 2063
Query: 1285 YENFKM-RYYILNENDTDIRRTFVIDPRNG--TLYLVRSPDREVKDTYEVIVRAE 1336
+ M +Y I + N+ + F+I+P G T+ R D EV+ +++V AE
Sbjct: 2064 TSDEGMIKYNIFSGNENE---AFIINPVTGDITVNDQRLLDFEVQRKVQLVVLAE 2115
Score = 89.0 bits (211), Expect = 9e-16
Identities = 106/472 (22%), Positives = 196/472 (41%), Gaps = 34/472 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+ V +L + D P Y FS+ +A VG+ +G V+A+ P +V Y + S
Sbjct: 762 NITVNILQS-DQPPALFQKAQYTFSISEDAPVGSSVGLVQAITP-ANSVEVVSYVI---S 816
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F I+ TG ++ A+ L+ +V + Q + +S A V + +T
Sbjct: 817 SGDPQGFFSIDSQTGIINTAQP--LDHESISYVILNIQFHTGTLPIHSSAQVNVSIT--D 872
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-NDVSYDLLHGYEEGVPFAV 622
+ P P F + GT + +D N + +LH + F +
Sbjct: 873 INDNP--PVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLH--PKSHLFTI 928
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
G + + D+SR + Y+ +A ++ + S+ + + V++++ V A
Sbjct: 929 HPNLGTLMLNGDVSRDSSSRYELSIIA-EDEGHPSLSSTLGL-VIEMDSSASVDDTLAFE 986
Query: 683 PIIFHVKENSAGAAIGQIF----HTNMSSIYGNG---TGNVRFLIANQQDVTDDIAIAED 735
+++ V+ + ++ H N S G T + + + V E
Sbjct: 987 TLVYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPET 1046
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G +F + LD E YR V A+ + V + ++DENDN PVF Y
Sbjct: 1047 GWMFVSQSLDYETEPSYRFCVCAKAQNSKMEATAT--VVVMVQDENDNAPVFSRDVYFFS 1104
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG-VVKFIGDSLD 854
+ E I +KA+D D N + + L +GK F V+ TG ++ + +LD
Sbjct: 1105 VQEGPSPHGLI---GTVKASDRDSLNNGVLSFILLTDGK-YFSVNSRTGEIINLV--ALD 1158
Query: 855 REKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
RE++ + L ++ D G L++ + I + D NDN+P+F + ++ +
Sbjct: 1159 REEQAQHVLRVMVTDQGRPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNV 1210
Score = 87.0 bits (206), Expect = 3e-15
Identities = 107/388 (27%), Positives = 155/388 (39%), Gaps = 47/388 (12%)
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
+T VV + D K L++ GG + + G NKP N + +
Sbjct: 2360 DTFVVSVLATDKDSGKNGRVSYRLLSSPVGGFYIDPDN----GSVFTNKP-LNYVANGNV 2414
Query: 902 VRIHRETKLNGTAG-FTI----IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
+R+ E + +G F + IEV N A Q IPE++ +G+T+I L A
Sbjct: 2415 LRLLVEARDSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAE 2474
Query: 957 DLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--F 1013
D D S N + Y S L +++ + + + G +++ +L E+ +
Sbjct: 2475 DKDYSDENTHLEYLIISGNDERRFCLEVVSIQAEPH---SRTVGQLVLCDTLDRETTDAY 2531
Query: 1014 RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
L ++ D G LN + V V V D+ND+ P F Y+ V E VL +V A D
Sbjct: 2532 SLTVTVTDRGINPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYD 2591
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX-XX 1130
D G N +TY I ++ + TGV+ VNG LD E + K LTV A D G
Sbjct: 2592 PDLGANGTITYNIISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDK 2651
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
D NDNSP F M P Y ++ EN
Sbjct: 2652 KVSFAVVYILVLDENDNSPFF--------------------------MFPTYNCSVSENL 2685
Query: 1191 PIGTTVAKVFANDTDFIGNGNGLILYSL 1218
P T V V A D D GL+ YS+
Sbjct: 2686 PAFTPVCTVHAVDED--AGTFGLLSYSI 2711
Score = 83.4 bits (197), Expect = 4e-14
Identities = 86/319 (26%), Positives = 135/319 (42%), Gaps = 29/319 (9%)
Query: 590 TSVGQIRVNDAFEQNDVSYDLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEA 647
T VG IR + + + + V F ++ +G+I+ L R Y+F A
Sbjct: 40 TIVGDIRAGLPAKTQSSGFFISESRDSEVFRDFEIDGDTGIISTAVVLDRERTDKYEFAA 99
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
L V ++ V DVND + +K H +V E S ++
Sbjct: 100 ATLTGE-----VIKVSIQVTDVNDNFPIFPVKIIH----LNVSELSPPGTRFELEGAQDK 150
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGT------IFTQKPLDREKRDVYRMTVIAEF 760
GT R +++ + I +G + Q LDRE D Y T+ A F
Sbjct: 151 DEGDYGTQGYRITDGEMRELFK-VEIRSNGVGMFNLDLVLQTRLDREIADFYNFTIEA-F 208
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ GV G Q I + DENDN PVF + Y I+EN+ + T + I ATDAD G
Sbjct: 209 DGGVPPKTGQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQ---IFATDADLG 265
Query: 821 TNALFMYTL---FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSS 875
+N +Y + + E F + ++G++ + LD E + Y+L + A D+G SS
Sbjct: 266 SNGQVIYGINRRQSDPNEFFIIGSSSGIIS-VNKHLDYENESYYELIVTAWDSGIQPESS 324
Query: 876 EAELIIMIGDENDNKPEFN 894
+ I + + NDN P +
Sbjct: 325 NTFVSIKVLNVNDNPPNIS 343
Score = 83.4 bits (197), Expect = 4e-14
Identities = 61/222 (27%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE 234
E + ++ VLD + F + +A + L + A D+D G + Y
Sbjct: 1498 ERKNASIIAQMIVLDINDNSPTFVSMDIACVPEDTEVGLLVHHVMAKDKDEGRNGHVTYS 1557
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ SGN++ F ++S G LFL LD +++H +L VQA P ++ + +
Sbjct: 1558 VSSGNEKSYFHMEST-GHLFLNSSLDYESQH-----VHILIVQARDNGVPSLSSTQTLTV 1611
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AF 352
++LD+ND+ P F+ YN +++EN G ++QV D D N +Y L G F
Sbjct: 1612 KVLDVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGPGYELF 1671
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
I+ +G ++ LDRE S+ ++V A+++ PS+ T
Sbjct: 1672 RINSHTGHIS--TSVRLDREIQSTFTLRVQAEDSGTPSLSST 1711
Score = 83.4 bits (197), Expect = 4e-14
Identities = 73/230 (31%), Positives = 108/230 (46%), Gaps = 17/230 (7%)
Query: 159 VHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASG---KRIHKEILFP 215
VH IV D+G +L S+ L KVLD + FQ I + R EI+
Sbjct: 1588 VHILIVQARDNGVPSLSSTQT---LTVKVLDVNDHPPVFQQHIYNTTVIENRDPGEIIVQ 1644
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ +D D V + + Y L+ G +LF ++S G + LD + + +TF L+
Sbjct: 1645 --VTTVDLDSEVNSAVSYSLLPGPGYELFRINSHTGHISTSVRLDREIQ-----STFTLR 1697
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA P ++ V +LD NDN P+F +I I ENL G + V A+D D
Sbjct: 1698 VQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDN 1756
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG Y ++D + FSID +G +R LDRE S+ + + A +
Sbjct: 1757 GLNGTIQYSIEDLE-CFSIDAVTG--MIRTTRPLDREERSNYSLLITAAD 1803
Score = 83.4 bits (197), Expect = 4e-14
Identities = 53/161 (32%), Positives = 81/161 (50%), Gaps = 4/161 (2%)
Query: 992 FVINERHGHVIV--ARSLPPESEFRLNISAL-DGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
F+IN G + V R L E + ++ + L + G+ V + ++D+ND+ PVFK++
Sbjct: 2083 FIINPVTGDITVNDQRLLDFEVQRKVQLVVLAENGHQTAYARVAITLQDINDNAPVFKQS 2142
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+Y V E Q + +V ATD+D G N ++YFI + + F I + G+L+ N L
Sbjct: 2143 YYRTAVWEGQIHNTYVMQVLATDSDSGVNGQISYFIMDGNHNNAFVIDSVRGILATNAVL 2202
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
DRE Y L + A+D G DVNDNSP
Sbjct: 2203 DREIVSSYKLIIQAKDMG-KAPLTGTCTVRVQVVDVNDNSP 2242
Score = 82.6 bits (195), Expect = 8e-14
Identities = 122/497 (24%), Positives = 194/497 (39%), Gaps = 53/497 (10%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ D + + + +LD NDN+PVF + Y+ + T + V A D D
Sbjct: 2314 TLKVQASDSVHQTEAELSIQVLDVNDNSPVFSQES-YQVLLSERTLADTFVVSVLATDKD 2372
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHA-LFVEASDQPANP 545
G+NG V Y L + F I+P+ G+V + + + G L VEA D +P
Sbjct: 2373 SGKNGRVSYRLLSSP----VGGFYIDPDNGSVFTNKPLNYVANGNVLRLLVEARDS-GDP 2427
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFE 602
+ + + V IEV + P F Y+ + +V +G+++ + D + E
Sbjct: 2428 N--LFCVTSVDIEVA----DFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDE 2481
Query: 603 QNDVSYDLLHGYEEG------VPFAVEERS---GVITVVDDLSRYNRPMYDFEAVALQEN 653
+ Y ++ G +E V E S G + + D L R Y
Sbjct: 2482 NTHLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRG 2541
Query: 654 AN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGN 711
N L+ T +V V+D+ND + V ENS G + Q+ + + N
Sbjct: 2542 INPLNSSTVVSVKVLDINDNAPAFSSPEYHA---QVSENSPVGLVLVQVSAYD-PDLGAN 2597
Query: 712 GTGNVRFLIANQQD-VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAG 769
GT + N + +T D + G I LD E+ +TV A ++
Sbjct: 2598 GTITYNIISGNSKGLITVD---SSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVS 2654
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
V I + DENDN P F TY + EN T + + A D D GT L Y++
Sbjct: 2655 FAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPV---CTVHAVDEDAGTFGLLSYSI 2711
Query: 830 F-----------GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
+ KE F +D TG + + D E + + ARD G +
Sbjct: 2712 VTPCFVDYDSSNPDKKEAFGIDPLTGDI-HTKQTFDYEGDRNFCFVVEARDKGDQVATLR 2770
Query: 879 LIIMIGDENDNKPEFNQ 895
+ I I ++ P F Q
Sbjct: 2771 VRIEIEGIDEFSPIFTQ 2787
Score = 79.8 bits (188), Expect = 5e-13
Identities = 59/185 (31%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLG T+ Y +ISGN + L ++DS G + + LD + + L T +Q
Sbjct: 2587 VSAYDPDLGANGTITYNIISGNSKGLITVDSSTGVIKVNGTLDYEEDTKL---TLTVQAS 2643
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++ K + A V I +LD NDN P F YN S+ ENLP V V A D+D G
Sbjct: 2644 DWGTSDDKKVSFAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGT 2703
Query: 338 NGEFTYQL------------DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +Y + D K AF IDP +G + + D E + V A++
Sbjct: 2704 FGLLSYSIVTPCFVDYDSSNPDKKEAFGIDPLTG--DIHTKQTFDYEGDRNFCFVVEARD 2761
Query: 386 TNPSV 390
V
Sbjct: 2762 KGDQV 2766
Score = 79.0 bits (186), Expect = 9e-13
Identities = 48/141 (34%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L ++A D G L+ I+ ++ V DVND+ PVF +T Y +++E + +V AT
Sbjct: 418 YELTVTASDYGCPPLSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKAT 477
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G ++ + Y I S+ PF I P GV++ LD E E + VVA D G
Sbjct: 478 DKDLGGDSEIIYSIVQSEQKCPFNIDPTLGVITTAAALDHERERELRFLVVASDGG-SPS 536
Query: 1131 XXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 537 LSSTATVIIHVEDVNDNKPIF 557
Score = 79.0 bits (186), Expect = 9e-13
Identities = 51/168 (30%), Positives = 82/168 (48%), Gaps = 9/168 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D GV + Y ++ GN F +DSV G L LD + +++ L +QA
Sbjct: 2163 ATDSDSGVNGQISYFIMDGNHNNAFVIDSVRGILATNAVLDREI-----VSSYKLIIQAK 2217
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ T V ++++D+NDN P ++I ENLP G+ V +V+A D D +
Sbjct: 2218 DMGKAPLTGTCTVRVQVVDVNDNSPTIP-SMEAVTIAENLPLGYIVTRVIANDVDLSPSA 2276
Query: 340 EF-TYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ + DD +F+ID +G +T +LD E S +KV A ++
Sbjct: 2277 TYRLIEKDDTSRSFAIDLYTGIITTTK--ILDYEEQSVYTLKVQASDS 2322
Score = 78.2 bits (184), Expect = 2e-12
Identities = 58/170 (34%), Positives = 92/170 (54%), Gaps = 15/170 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D DL AT Y LI +D + F++D G + K LD + + + + L+VQA
Sbjct: 2267 ANDVDLSPSAT--YRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQ-----SVYTLKVQA 2319
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S + + +A + I++LD+NDN P F + Y + + E V+ V+ATDKD G+N
Sbjct: 2320 S---DSVHQTEAELSIQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVLATDKDSGKN 2376
Query: 339 GEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSS-LRMKVYAKET 386
G +Y+ L P G F IDP +G +V L+ A+ + LR+ V A+++
Sbjct: 2377 GRVSYRLLSSPVGGFYIDPDNG--SVFTNKPLNYVANGNVLRLLVEARDS 2424
Score = 76.6 bits (180), Expect = 5e-12
Identities = 95/356 (26%), Positives = 157/356 (44%), Gaps = 26/356 (7%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISA-LDGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
F I+ G + V++SL E+E +R + A + +V V V+D ND+ PVF +
Sbjct: 1040 FRIHPETGWMFVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSRD 1099
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
Y F+V+E ++G V A+D D N L+ FI +D F ++ TG + L
Sbjct: 1100 VYFFSVQEGPSPHGLIGTVKASDRDSLNNGVLS-FILLTDGKY-FSVNSRTGEIINLVAL 1157
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY---AFDELLEWKHPEA 1165
DRE + +++L V+ D G DVNDN P+F + EL W
Sbjct: 1158 DREEQAQHVLRVMVTDQG-RPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNVWAVIPV 1216
Query: 1166 DELSNHNFESVMMI---PVYKATIEENAPIGTTVAKVFANDTDFIG--NGNGLILYSLPQ 1220
+ + F + K ++ +N +G + D + N + Y+L
Sbjct: 1217 NSVVISMFAKDLDAGENGTVKFSMTDN-QLGHFSIDSLSGDVKVTSQFSSNPQMRYTL-- 1273
Query: 1221 RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
R + GL L TA++ + V V D+ K F S + + E+V + SL
Sbjct: 1274 RVVATDNGLFPLEETAVVHIQVY-VLDQ----QKENFQSSFQHFTVLEDVGLGTIIGSLG 1328
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
++ + + ++RY I+ N + F I +G LY+ + D EV Y ++VRAE
Sbjct: 1329 VS-NAPDTELRYSIVEGNGS---LQFGIKSSSGELYVAQHLDYEVTQRYFLVVRAE 1380
Score = 75.8 bits (178), Expect = 9e-12
Identities = 76/319 (23%), Positives = 132/319 (41%), Gaps = 26/319 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAP-IGPSLTI 130
G+N +++ V+V + D+NDN P F YH V E +P G + P +G + TI
Sbjct: 2541 GINPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYDPDLGANGTI 2600
Query: 131 PLTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+ G +T+ + D ++ D + + ++
Sbjct: 2601 TYNIISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSFAVVYI 2660
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPE-PIHAIDQDLGVGATLRYELI-------- 236
VLD + F + P +HA+D+D G L Y ++
Sbjct: 2661 LVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVTPCFVDYD 2720
Query: 237 -SGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
S D+K F +D + G + ++ D + + N F V+A + + T + R+EI
Sbjct: 2721 SSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRN-----FCFVVEARDKGDQVATLRVRIEI 2775
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
E +D + P F + Y+ S+ N G S+ +MA D D G +G Y L P F++
Sbjct: 2776 EGID--EFSPIFTQNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSLVSPSSFFNV 2833
Query: 355 DPRSGWLTVRNQTVLDREA 373
+ +G L V N +V R++
Sbjct: 2834 NKTNGCLFVSN-SVYQRQS 2851
Score = 73.7 bits (173), Expect = 3e-11
Identities = 54/181 (29%), Positives = 82/181 (45%), Gaps = 6/181 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD-SVNGSLFLEKELDLDAEHNLQ-ANTFVLQVQ 277
A D+D G T Y + G R+LF ++ NG +L L + + A+ + ++
Sbjct: 147 AQDKDEGDYGTQGYRITDGEMRELFKVEIRSNGVGMFNLDLVLQTRLDREIADFYNFTIE 206
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P KT Q + +I +LD NDN P F Y+ I+EN V Q+ ATD D G
Sbjct: 207 AFDGGVPPKTGQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGS 266
Query: 338 NGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
NG+ Y ++ DP F I SG ++V + E++ L + + P T
Sbjct: 267 NGQVIYGINRRQSDPNEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSGIQPESSNT 326
Query: 394 F 394
F
Sbjct: 327 F 327
Score = 73.3 bits (172), Expect = 5e-11
Identities = 101/385 (26%), Positives = 153/385 (39%), Gaps = 45/385 (11%)
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ I A DGG + ++ V D ND+ PVF ++ Y+ + E + ++ AT
Sbjct: 201 YNFTIEAFDGGVPPKTGQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFAT 260
Query: 1071 DADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
DAD G N + Y I + SD + F I +G++SVN LD E E Y L V A D+G
Sbjct: 261 DADLGSNGQVIYGINRRQSDPNEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSG-I 319
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
+VNDN P L E PE E + + V I V + +
Sbjct: 320 QPESSNTFVSIKVLNVNDNPPNISVL-FLNEAGAPEVSEGAGFE-DYVARIAVSDPDLGD 377
Query: 1189 NAPIGTTVA---KVFA----NDTDFIGNGNGLI------LYSLPQRKNQQNLGLPSLSST 1235
I + +F+ +D ++ +G + LY L + G P LSS
Sbjct: 378 VKKIDVLLQGGDGMFSLRSMDDFLYVLCVDGPLDREIKDLYEL--TVTASDYGCPPLSSV 435
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYIL 1295
+ V DV D + PVF YE I+E+V + + T+ I
Sbjct: 436 ITFQIQVTDVND-----NPPVFHQTIYEESIDEDVRVGTAVFRVKATDKDLGGDSE-IIY 489
Query: 1296 NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDV 1355
+ ++ + F IDP G + + D E REL ++ VA D
Sbjct: 490 SIVQSEQKCPFNIDPTLGVITTAAALDHE---------------RERELRFLV--VASDG 532
Query: 1356 LEGMTKYDVKVVVRIKDVNDNSPKF 1380
V++ ++DVNDN P F
Sbjct: 533 GSPSLSSTATVIIHVEDVNDNKPIF 557
Score = 72.5 bits (170), Expect = 8e-11
Identities = 91/339 (26%), Positives = 148/339 (43%), Gaps = 27/339 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYH-VTVDELTPTGEKAFIFLI-APIGPSLTI 130
G+ + L + + D NDN P+F + YH V ++ T IF A +G + +
Sbjct: 211 GVPPKTGQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGSNGQV 270
Query: 131 PLTVPRGLT-------IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+ R + I +K ++ +Y ++ D ESS+ V +
Sbjct: 271 IYGINRRQSDPNEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSGIQPESSNTFVSI 330
Query: 184 LRKVLDYDAGDKEFQLVIM--ASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISG 238
KVL+ + ++ + A + + F + + I D DLG + L+ G
Sbjct: 331 --KVLNVNDNPPNISVLFLNEAGAPEVSEGAGFEDYVARIAVSDPDLGDVKKIDV-LLQG 387
Query: 239 NDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
D +FSL S++ L+ L + LD E + + L V AS P ++ +I++
Sbjct: 388 GDG-MFSLRSMDDFLYVLCVDGPLDREIK---DLYELTVTASDYGCPPLSSVITFQIQVT 443
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
D+NDN P F Y SI E++ G +V +V ATDKD G + E Y + + K F+ID
Sbjct: 444 DVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKATDKDLGGDSEIIYSIVQSEQKCPFNID 503
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
P G +T LD E LR V A + +PS+ T
Sbjct: 504 PTLGVIT--TAAALDHERERELRFLVVASDGGSPSLSST 540
Score = 72.1 bits (169), Expect = 1e-10
Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 11/167 (6%)
Query: 231 LRYELISGNDRKLFSLDSVN-----GSLFLEKELDLDAEHNLQANTFVLQVQASQLN-NP 284
L Y +ISGND + F L+ V+ S + + + D + + L V + NP
Sbjct: 2485 LEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRGINP 2544
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
L ++ V +++LD+NDN P F Y+ + EN P G ++QV A D D G NG TY
Sbjct: 2545 LNSSTV-VSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYDPDLGANGTITYN 2603
Query: 345 L--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+ + KG ++D +G + V LD E + L + V A + S
Sbjct: 2604 IISGNSKGLITVDSSTGVIKVNG--TLDYEEDTKLTLTVQASDWGTS 2648
Score = 71.7 bits (168), Expect = 1e-10
Identities = 111/480 (23%), Positives = 190/480 (39%), Gaps = 42/480 (8%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I EN + T + ++ A D D G NGQ+ Y N P +F+I
Sbjct: 243 VILENATLMTPVCQIFATDADLGSNGQVIYGINRRQSDP-----------NEFFIIGSSS 291
Query: 999 GHVIVARSLPPESE--FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNF-- 1052
G + V + L E+E + L ++A D G + N V + V +VND+ P + N
Sbjct: 292 GIISVNKHLDYENESYYELIVTAWDSGIQPESSNTFVSIKVLNVNDNPPNISVLFLNEAG 351
Query: 1053 --NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE-ISPLTGVLSVNGELD 1109
V E + ++ +D D G + +Q D + VL V+G LD
Sbjct: 352 APEVSEGAGFEDYVARIAVSDPDLGDVKKIDVLLQGGDGMFSLRSMDDFLYVLCVDGPLD 411
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RE +D Y LTV A D G DVNDN P F+ + E E +
Sbjct: 412 REIKDLYELTVTASDYG-CPPLSSVITFQIQVTDVNDNPPVFH--QTIYEESIDEDVRVG 468
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
F E I + K N +G + + + L +
Sbjct: 469 TAVFRVKATDKDLGGDSEIIYSIVQSEQKCPFNIDPTLGVITTAAALDHERERELRFLVV 528
Query: 1230 PSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYELEIEEN--VNAPVELVSLNLTEHYE 1286
S + L T + +++D KP+F ++Y ++E+ V + V+ + E
Sbjct: 529 ASDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAE 588
Query: 1287 NFKMRYYILNE-NDTDIRRTFVIDPRNGTLYLVRSPDREV-KDTYEVIVRAERQKYSREL 1344
++Y++ + + D+ F I+ G + + + D E T++++++AE Q
Sbjct: 589 FGSVQYFLYDGFSGKDVHPFFHINSVTGNICVSQDIDYEAGLLTFDLLIKAEDQ------ 642
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ +D T V + I+DVNDN+P F G VT++ A G +++ +
Sbjct: 643 --VSLSFVKDGFSSQT----FVHIGIEDVNDNAPVFNPGK--YVTSVSVHAQPGTELLNV 694
Score = 71.7 bits (168), Expect = 1e-10
Identities = 143/610 (23%), Positives = 240/610 (39%), Gaps = 102/610 (16%)
Query: 710 GNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG 769
G+ T R I QD+ D+ + + + + + + + Y M V+A + ++G
Sbjct: 2117 GHQTAYARVAIT-LQDINDNAPVFKQ-SYYRTAVWEGQIHNTYVMQVLATDSDSGVNG-- 2172
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
Q++ +I D N N F + G + N+ + EI + D G L
Sbjct: 2173 --QISYFIMDGNHNN-AFVIDSVRGILATNAVLDREIVSSYKLIIQAKDMGKAPLTGTCT 2229
Query: 830 FGEGKEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEND 888
++ DV++N+ + + ++ + Y ++ V + LS A ++ D+
Sbjct: 2230 VRV--QVVDVNDNSPTIPSMEAVTIAENLPLGYIVTRVIANDVDLSPSATYRLIEKDDTS 2287
Query: 889 NK---PEFNQIEENSKVRIHRETK---LNGTAGFTIIEVKPKNKF-ALDVDQLGPLF--- 938
+ I +K+ + E L A ++ + + + LDV+ P+F
Sbjct: 2288 RSFAIDLYTGIITTTKILDYEEQSVYTLKVQASDSVHQTEAELSIQVLDVNDNSPVFSQE 2347
Query: 939 ----LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE----VYIPPSKLSADALEVKR 990
L+ E T ++ + A D DSG NG++ Y S YI P S +
Sbjct: 2348 SYQVLLSERTLADTFVVSVLATDKDSGKNGRVSYRLLSSPVGGFYIDPDNGSVFTNKPLN 2407
Query: 991 YFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKT 1048
Y +G+V+ RL + A D G NL SV + V D ND+ P F +
Sbjct: 2408 YVA----NGNVL-----------RLLVEARDSGDPNLFCVTSVDIEVADFNDNAPFFTQN 2452
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDTDLPF--EI--------SP 1097
Y N+ E L + A D D+ +N +L Y I + + F E+ S
Sbjct: 2453 SYQINIPEDVSVGSTLITLLAEDKDYSDENTHLEYLIISGNDERRFCLEVVSIQAEPHSR 2512
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
G L + LDRET D Y LTV D G D+NDN+P F +
Sbjct: 2513 TVGQLVLCDTLDRETTDAYSLTVTVTDRG-INPLNSSTVVSVKVLDINDNAPAFSS---- 2567
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
P Y A + EN+P+G + +V A D D NG I Y+
Sbjct: 2568 ----------------------PEYHAQVSENSPVGLVLVQVSAYDPDL--GANGTITYN 2603
Query: 1218 LPQRKNQQNLGLPSL-SSTAILMVT-VADVPDEVEMS------------DKPVFISRYYE 1263
+ ++ GL ++ SST ++ V D ++ +++ DK V + Y
Sbjct: 2604 IISGNSK---GLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSFAVVYI 2660
Query: 1264 LEIEENVNAP 1273
L ++EN N+P
Sbjct: 2661 LVLDENDNSP 2670
Score = 71.3 bits (167), Expect = 2e-10
Identities = 76/333 (22%), Positives = 146/333 (43%), Gaps = 29/333 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFI-------------F 119
G +S+ ++ + + DVNDN P+F T Y ++DE G F
Sbjct: 428 GCPPLSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKATDKDLGGDSEI 487
Query: 120 LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
+ + + P + L + A D ++ ++ + +V+ +D G +L S+
Sbjct: 488 IYSIVQSEQKCPFNIDPTLGVITTAAALDHERER----ELRFLVVA-SDGGSPSLSSTAT 542
Query: 180 PVLLLRKVLDYDA-GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISG 238
++ + V D ++F + + IL I A + G Y+ SG
Sbjct: 543 VIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAEFGSVQYFLYDGFSG 602
Query: 239 ND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK---TAQARVEI 294
D F ++SV G++ + +++D +A L +++ + + +K ++Q V I
Sbjct: 603 KDVHPFFHINSVTGNICVSQDIDYEA--GLLTFDLLIKAEDQVSLSFVKDGFSSQTFVHI 660
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAF 352
+ D+NDN P F Y S+ + G +L V A+D+D G G+ TY+L D F
Sbjct: 661 GIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQPGDSATLF 720
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++D +G +V + L + SS+++ V A++
Sbjct: 721 TMDQSTG--SVYLSSSLMQLRSSSVKLSVSARD 751
Score = 71.3 bits (167), Expect = 2e-10
Identities = 94/362 (25%), Positives = 142/362 (39%), Gaps = 27/362 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I G + VA+ L E + L + A N + V + DVNDH P F
Sbjct: 1350 FGIKSSSGELYVAQHLDYEVTQRYFLVVRAEAFPTFNVTVFAAVSILDVNDHNPWFPSNG 1409
Query: 1050 --YNFNVEEAQYTRRVLGKVDATDADFGQNAN-----LTYFIQPSDTDLPFEISPLTGVL 1102
F V E V+ +A D D + + LT+ P+ LP I P TGV+
Sbjct: 1410 NIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAIEGLPLHIDPHTGVV 1469
Query: 1103 SVNGELDRETEDKYILTVVARDN--GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
+ NG+LDRE + I V A D+ D+NDNSP F + D
Sbjct: 1470 TTNGQLDRERTENIIFRVTASDSLKEPNERKNASIIAQMIVLDINDNSPTFVSMDIACVP 1529
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
+ E L H+ + + + G + T + + L S
Sbjct: 1530 EDTEVG-LLVHHVMAKDKDEGRNGHVTYSVSSGNEKSYFHMESTGHLFLNSSLDYESQHV 1588
Query: 1221 R---KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP---V 1274
++ G+PSLSST L V V DV D PVF Y + EN + V
Sbjct: 1589 HILIVQARDNGVPSLSSTQTLTVKVLDVNDH-----PPVFQQHIYNTTVIENRDPGEIIV 1643
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
++ +++L N + Y +L ++ F I+ G + DRE++ T+ + V+
Sbjct: 1644 QVTTVDLDSEV-NSAVSYSLLPGPGYEL---FRINSHTGHISTSVRLDREIQSTFTLRVQ 1699
Query: 1335 AE 1336
AE
Sbjct: 1700 AE 1701
Score = 70.9 bits (166), Expect = 2e-10
Identities = 126/462 (27%), Positives = 191/462 (41%), Gaps = 77/462 (16%)
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
T ++++ A D DSG+NGQI Y +I + FVI+ G + L
Sbjct: 2156 TYVMQVLATDSDSGVNGQISY------FIMDGNHN-------NAFVIDSVRGILATNAVL 2202
Query: 1008 PPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV 1063
E S ++L I A D G L +VRV V DVND+ P + + E +
Sbjct: 2203 DREIVSSYKLIIQAKDMGKAPLTGTCTVRVQVVDVNDNSPTIP-SMEAVTIAENLPLGYI 2261
Query: 1064 LGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+ +V A D D +A TY I+ DT F I TG+++ LD E + Y L V A
Sbjct: 2262 VTRVIANDVDLSPSA--TYRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQSVYTLKVQA 2319
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD-ELLEWKHPEADE-----LSNHNFESV 1176
D+ DVNDNSP F ++L + AD L+
Sbjct: 2320 SDS----VHQTEAELSIQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVLATDKDSGK 2375
Query: 1177 MMIPVYKATIEENAPIG-----TTVAKVFAN-DTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
Y+ ++P+G VF N +++ NGN +L L + ++ G P
Sbjct: 2376 NGRVSYRLL---SSPVGGFYIDPDNGSVFTNKPLNYVANGN--VLRLLVEARDS---GDP 2427
Query: 1231 SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE-HY--EN 1287
+L + + VAD D + P F Y++ I E+V+ L++L + Y EN
Sbjct: 2428 NLFCVTSVDIEVADFND-----NAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDEN 2482
Query: 1288 FKMRYYILNENDTDIRRTFVI----DPRN---GTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ Y I++ ND V+ +P + G L L + DRE D Y + V +
Sbjct: 2483 THLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRG- 2541
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
I P L T VKV+ D+NDN+P F++
Sbjct: 2542 -------INP-----LNSSTVVSVKVL----DINDNAPAFSS 2567
Score = 69.7 bits (163), Expect = 6e-10
Identities = 127/519 (24%), Positives = 202/519 (38%), Gaps = 65/519 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +P+GT I+ L A D D G NG + + E F ++ G
Sbjct: 1838 ISEGLPVGTEILHLIAWDPDEGANGVVTFSLEEEN--------------SGNFHVDGSTG 1883
Query: 1000 HVIVARSLPPE--SEFRLNISALDG---GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + + L E S+ A DG G + +V + V+D+ND+ P K +V
Sbjct: 1884 VIKLTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKEPMRVSV 1943
Query: 1055 EEAQYT-RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
R + KV A D D G N + + + P + +L F++ +G + + L E
Sbjct: 1944 SSVNTRPNRPIAKVTAQDPDLGDNGTVVFRL-PEEDEL-FQVDG-SGAVRLKAPLSNEVS 2000
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+L + A D G +ND P +EL E PE + +
Sbjct: 2001 GTKLLRIRAEDLGRPSLTSSCLLLI----QLNDEEPLLQFTEELYEVAVPENSKTGSWVA 2056
Query: 1174 ESVMMIPVY-KATIEENAPIGTTVAKVFANDT--DFIGNGNGLILYSLPQRKNQQNLGLP 1230
V + I+ N G N D N L+ + + QRK Q +
Sbjct: 2057 NVVAHDQTSDEGMIKYNIFSGNENEAFIINPVTGDITVNDQRLLDFEV-QRKVQLVVLAE 2115
Query: 1231 SLSSTAI--LMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYE 1286
+ TA + +T+ D+ D PVF YY + E N V V ++
Sbjct: 2116 NGHQTAYARVAITLQDINDNA-----PVFKQSYYRTAVWEGQIHNTYVMQVLATDSDSGV 2170
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N ++ Y+I++ N + FVID G L DRE+ +Y++I++A+
Sbjct: 2171 NGQISYFIMDGNHNN---AFVIDSVRGILATNAVLDREIVSSYKLIIQAK---------- 2217
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ-LK 1405
+ + L G V+VV DVNDNSP T + VT I P GY V + +
Sbjct: 2218 ---DMGKAPLTGTCTVRVQVV----DVNDNSP--TIPSMEAVT-IAENLPLGYIVTRVIA 2267
Query: 1406 GAIGHHPTAS-RTVRADTDELVFFERLSLNGLTSPQATD 1443
+ P+A+ R + D F L +T+ + D
Sbjct: 2268 NDVDLSPSATYRLIEKDDTSRSFAIDLYTGIITTTKILD 2306
Score = 67.7 bits (158), Expect = 2e-09
Identities = 64/197 (32%), Positives = 94/197 (47%), Gaps = 22/197 (11%)
Query: 718 FLIANQQD--VTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
F I+ +D V D I D G I T LDRE+ D Y EF ++G + +V+
Sbjct: 58 FFISESRDSEVFRDFEIDGDTGIISTAVVLDRERTDKY------EFAAATLTGE-VIKVS 110
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEG 833
I + D NDN P+F + E S GT +++ A D DEG Y + GE
Sbjct: 111 IQVTDVNDNFPIFPVKIIHLNVSELSPPGTRFELEG---AQDKDEGDYGTQGYRITDGEM 167
Query: 834 KEMFDVD-ENTGVVKF-----IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
+E+F V+ + GV F + LDRE Y ++ A D G + + + I + D
Sbjct: 168 RELFKVEIRSNGVGMFNLDLVLQTRLDREIADFYNFTIEAFDGGVPPKTGQLQAQITVLD 227
Query: 886 ENDNKPEFNQIEENSKV 902
ENDN+P FNQ E ++ +
Sbjct: 228 ENDNQPVFNQSEYHAVI 244
Score = 64.5 bits (150), Expect = 2e-08
Identities = 59/197 (29%), Positives = 90/197 (45%), Gaps = 19/197 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT I+++ A+D D EF S Y S +V +F IN G
Sbjct: 566 VKEHTAVGTCILQVTAIDADGA-------EFGSVQYFLYDGFSGK--DVHPFFHINSVTG 616
Query: 1000 HVIVARSLPPES---EFRLNISALDGGNLN---DNISVRVFV----KDVNDHFPVFKKTW 1049
++ V++ + E+ F L I A D +L+ D S + FV +DVND+ PVF
Sbjct: 617 NICVSQDIDYEAGLLTFDLLIKAEDQVSLSFVKDGFSSQTFVHIGIEDVNDNAPVFNPGK 676
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y +V L V A+D D G +TY +QP D+ F + TG + ++ L
Sbjct: 677 YVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQPGDSATLFTMDQSTGSVYLSSSLM 736
Query: 1110 RETEDKYILTVVARDNG 1126
+ L+V ARD G
Sbjct: 737 QLRSSSVKLSVSARDGG 753
Score = 64.5 bits (150), Expect = 2e-08
Identities = 81/328 (24%), Positives = 133/328 (40%), Gaps = 23/328 (7%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
++ G I + V V I D+NDN P+F T H+T+ TP G FI
Sbjct: 851 IQFHTGTLPIHSSAQVNVSITDINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSG 910
Query: 128 LTIPLTV---PRG--LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPV 181
+ P+ TI ++ + + +S Y + + D+GH +L S+ V
Sbjct: 911 FNGRIHYMLHPKSHLFTIHPNLGTLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLV 970
Query: 182 LLLRKVLDYDAGDKEFQLVIMAS-GKRIHKEI-LFPEPIHAI-DQDLGVG----ATLRYE 234
+ + D LV G+ K+ + H Q G + + Y
Sbjct: 971 IEMDSSASVDDTLAFETLVYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYS 1030
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
L + F + G +F+ + LD + E + + F + +A N A A V +
Sbjct: 1031 LKPLSGVPPFRIHPETGWMFVSQSLDYETEPSYR---FCVCAKAQ---NSKMEATATVVV 1084
Query: 295 ELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFS 353
+ D NDN P F D Y S+ E P+G + V A+D+D NG ++ L FS
Sbjct: 1085 MVQDENDNAPVFSRDVYFFSVQEGPSPHGL-IGTVKASDRDSLNNGVLSFILLTDGKYFS 1143
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKV 381
++ R+G + N LDRE + ++V
Sbjct: 1144 VNSRTG--EIINLVALDREEQAQHVLRV 1169
Score = 63.3 bits (147), Expect = 5e-08
Identities = 45/162 (27%), Positives = 77/162 (47%), Gaps = 9/162 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y + SG+ + FS+DS G + + LD ++ + +L +Q P+ ++ A+V
Sbjct: 813 YVISSGDPQGFFSIDSQTGIINTAQPLDHES-----ISYVILNIQFHTGTLPIHSS-AQV 866
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF 352
+ + D+NDN P F+ +I+I P G + A D D G NG Y L F
Sbjct: 867 NVSITDINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSHLF 926
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK-ETNPSVVGT 393
+I P G L + + R++ S + + A+ E +PS+ T
Sbjct: 927 TIHPNLGTLMLNGD--VSRDSSSRYELSIIAEDEGHPSLSST 966
Score = 63.3 bits (147), Expect = 5e-08
Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 5/139 (3%)
Query: 991 YFVINERHGHVIVARSLPPES--EFRLNISALDGG-NLNDNISVRVFVKDVNDHFPVFKK 1047
+F I+ + G + A+ L ES LNI G ++ + V V + D+ND+ PVF+K
Sbjct: 823 FFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLPIHSSAQVNVSITDINDNPPVFQK 882
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
T + + L A D D G N + Y + P F I P G L +NG+
Sbjct: 883 TSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSH--LFTIHPNLGTLMLNGD 940
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ R++ +Y L+++A D G
Sbjct: 941 VSRDSSSRYELSIIAEDEG 959
Score = 60.9 bits (141), Expect = 3e-07
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 6/131 (4%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F + A D+D G + Y L+S F +D NGS+F K L+ A N
Sbjct: 2362 FVVSVLATDKDSGKNGRVSYRLLSSPVGG-FYIDPDNGSVFTNKPLNYVAN----GNVLR 2416
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V+A +P V+IE+ D NDN P F + Y I+I E++ G +++ ++A DK
Sbjct: 2417 LLVEARDSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDK 2476
Query: 334 D-QGENGEFTY 343
D EN Y
Sbjct: 2477 DYSDENTHLEY 2487
Score = 58.8 bits (136), Expect = 1e-06
Identities = 117/476 (24%), Positives = 191/476 (40%), Gaps = 46/476 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ ++ + V V + D NDN PVF ++Y FS++ +IG VKA D D NG++
Sbjct: 1073 NSKMEATATVVVMVQDENDNAPVF-SRDVYFFSVQEGPSPHGLIGTVKASDRDSLNNGVL 1131
Query: 496 LYDLQRTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ L LT F +N TG + VA + +H L V +DQ P R +
Sbjct: 1132 SFIL-----LTDGKYFSVNSRTGEIINLVALDREEQAQHVLRVMVTDQ-GRP--RLNTTT 1183
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLL 611
+ I VT N+P M + E V + + + + V + DA E V + +
Sbjct: 1184 TIHITVT-DVNDNRPQF-THMPSTKELNVWAVIPVNSVVISMFAKDLDAGENGTVKFSMT 1241
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVN 670
+ G F+++ SG + V S + Y VA +N + A VH+ V V
Sbjct: 1242 DN-QLG-HFSIDSLSGDVKVTSQFSSNPQMRYTLRVVA-TDNGLFPLEETAVVHIQVYVL 1298
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D++ + + +++ G IG + +N +R+ I
Sbjct: 1299 DQQKENFQSSFQHFTV-LEDVGLGTIIGSLGVSNAPDT------ELRYSIVEGNGSLQFG 1351
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAE----FNKGVISGAGIYQVTIYIEDENDNPPV 786
+ G ++ + LD E Y + V AE FN V + I V D N P
Sbjct: 1352 IKSSSGELYVAQHLDYEVTQRYFLVVRAEAFPTFNVTVFAAVSILDV----NDHNPWFPS 1407
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM----FDVDEN 842
+ G + E+ GT + + N + D + L+ F + +D +
Sbjct: 1408 NGNIVIFG-VHEDVSNGTVVYVFN-ARDGDGSLHYSELYYSLTFDPSPAIEGLPLHIDPH 1465
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE---AELI--IMIGDENDNKPEF 893
TGVV G LDRE+ + A D+ +E A +I +++ D NDN P F
Sbjct: 1466 TGVVTTNG-QLDRERTENIIFRVTASDSLKEPNERKNASIIAQMIVLDINDNSPTF 1520
Score = 57.6 bits (133), Expect = 2e-06
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 10/165 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D L + L++ D K FS++S G + + LD E Q VL+V
Sbjct: 1118 VKASDRDSLNNGVLSFILLT--DGKYFSVNSRTGEII--NLVALDREEQAQ---HVLRVM 1170
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFE--VDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ P + I + D+NDN P+F +++ +P V+ + A D D
Sbjct: 1171 VTDQGRPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNVWAVIPVNSVVISMFAKDLDA 1230
Query: 336 GENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
GENG + + D+ G FSID SG + V +Q + + +LR+
Sbjct: 1231 GENGTVKFSMTDNQLGHFSIDSLSGDVKVTSQFSSNPQMRYTLRV 1275
Score = 55.2 bits (127), Expect = 1e-05
Identities = 81/334 (24%), Positives = 137/334 (41%), Gaps = 28/334 (8%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL--T 129
+G +S+ +V + D NDN P F H+ + E G I + I L T
Sbjct: 1703 SGTPSLSSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDNGLNGT 1761
Query: 130 IPLTVP--RGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRK 186
I ++ +I +P +YS+ ++ D GH L SS + L
Sbjct: 1762 IQYSIEDLECFSIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTD 1821
Query: 187 VLDYDA--GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
D K ++ I + G + EIL + A D D G + + L N F
Sbjct: 1822 ENDNSPLFARKSYRASI-SEGLPVGTEILH---LIAWDPDEGANGVVTFSLEEENSGN-F 1876
Query: 245 SLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+D G + L K LD + ++H +A V + +++ A V I++ D+NDN
Sbjct: 1877 HVDGSTGVIKLTKPLDRETRSQHVFRA------VATDGCSEGPRSSIATVTIQVEDINDN 1930
Query: 303 LPEFEVDFYNISI--VENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
P + +S+ V PN + +V A D D G+NG ++L + F +D G
Sbjct: 1931 TPACVKEPMRVSVSSVNTRPNR-PIAKVTAQDPDLGDNGTVVFRLPEEDELFQVD---GS 1986
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
VR + L E + +++ A++ PS+ +
Sbjct: 1987 GAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSS 2020
Score = 54.4 bits (125), Expect = 2e-05
Identities = 121/514 (23%), Positives = 204/514 (39%), Gaps = 66/514 (12%)
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
EV R F I+ G + A L E + +A + I V + V DVND+FP+F
Sbjct: 67 EVFRDFEIDGDTGIISTAVVLDRERTDKYEFAAAT--LTGEVIKVSIQVTDVNDNFPIFP 124
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS-PLTGV---- 1101
+ NV E A D D G Y I + F++ GV
Sbjct: 125 VKIIHLNVSELSPPGTRFELEGAQDKDEGDYGTQGYRITDGEMRELFKVEIRSNGVGMFN 184
Query: 1102 --LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
L + LDRE D Y T+ A D G D NDN P F
Sbjct: 185 LDLVLQTRLDREIADFYNFTIEAFDGG-VPPKTGQLQAQITVLDENDNQPVF-------- 235
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP 1219
+ + +V++ ENA + T V ++FA D D NG ++Y +
Sbjct: 236 ---------NQSEYHAVIL---------ENATLMTPVCQIFATDADL--GSNGQVIYGIN 275
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
+R++ N SS+ I ++V D S + ++ + E+ N V + L
Sbjct: 276 RRQSDPNEFFIIGSSSGI--ISVNKHLDYENESYYELIVTAWDSGIQPESSNTFVSIKVL 333
Query: 1280 NLTEHYENFKMRYYILNE-NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
N+ ++ N + + LNE ++ + + V PD +V+++
Sbjct: 334 NVNDNPPNISVLF--LNEAGAPEVSEGAGFEDYVARI-AVSDPDLGDVKKIDVLLQGGDG 390
Query: 1339 KYS-RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPF 1397
+S R + +Y + D G + IKD+ + + ++ P ++++ T
Sbjct: 391 MFSLRSMDDFLYVLCVD---GPLDRE------IKDLYELTVTASDYGCPPLSSVIT---- 437
Query: 1398 GYQVMQLKGAIGHHPTASRTVRADT-DELVFFERLSLNGLTSPQATDSDIGINADIRYQI 1456
+Q+ Q+ + P +T+ ++ DE V R+ + +ATD D+G +++I Y I
Sbjct: 438 -FQI-QVTDVNDNPPVFHQTIYEESIDEDV---RVG-TAVFRVKATDKDLGGDSEIIYSI 491
Query: 1457 L-NEQAPRFAIDPVSGTVRVVAALARDAGRVFGF 1489
+ +EQ F IDP G + AAL + R F
Sbjct: 492 VQSEQKCPFNIDPTLGVITTAAALDHERERELRF 525
Score = 53.6 bits (123), Expect = 4e-05
Identities = 48/222 (21%), Positives = 97/222 (43%), Gaps = 16/222 (7%)
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP-------ENIPIGTT 949
EE++K+ + + GT+ + LD + P F+ P EN+P T
Sbjct: 2631 EEDTKLTLTVQASDWGTSDDKKVSFAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTP 2690
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+ ++A+D D+G G + Y + ++ + D E F I+ G + ++
Sbjct: 2691 VCTVHAVDEDAGTFGLLSYSIVTPCFVDYDSSNPDKKEA---FGIDPLTGDIHTKQTFDY 2747
Query: 1010 ESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
E + F + A D G+ + VR+ ++ +++ P+F + Y+F++ + +G +
Sbjct: 2748 EGDRNFCFVVEARDKGDQVATLRVRIEIEGIDEFSPIFTQNVYHFSLPANPKVGQSIGYL 2807
Query: 1068 DATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGEL 1108
A D D G + + Y + PS F ++ G L V+ +
Sbjct: 2808 MAMDHDGGLDGLVEYSLVSPSSF---FNVNKTNGCLFVSNSV 2846
Score = 53.6 bits (123), Expect = 4e-05
Identities = 51/173 (29%), Positives = 77/173 (44%), Gaps = 19/173 (10%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D++ +SF V + +LD NDN+P F+ Y S+ N T + V AVD D G G++
Sbjct: 2649 DDKKVSFAVVYILVLDENDNSPFFM-FPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLL 2707
Query: 496 LYDL-------QRTSNLTITSPFKINPNTGTVSVAESPILEG-RHALF-VEASDQPANPS 546
Y + +SN F I+P TG + ++ EG R+ F VEA D+
Sbjct: 2708 SYSIVTPCFVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKGDQ-- 2765
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
V T+ V +G P F Y F + +N +G S+G + D
Sbjct: 2766 -------VATLRVRIEIEGIDEFSPIFTQNVYHFSLPANPKVGQSIGYLMAMD 2811
Score = 51.6 bits (118), Expect = 2e-04
Identities = 52/214 (24%), Positives = 86/214 (40%), Gaps = 20/214 (9%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT ++ + A D D+G G+I YE D+ + F +++ G V ++ S
Sbjct: 688 GTELLNVYASDQDAGNYGKITYELQP----------GDSATL---FTMDQSTGSVYLSSS 734
Query: 1007 LPP--ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFP--VFKKTWYNFNVEEAQYTRR 1062
L S +L++SA DGG ++ + V + P +F+K Y F++ E
Sbjct: 735 LMQLRSSSVKLSVSARDGGGMSAAYPANITVNILQSDQPPALFQKAQYTFSISEDAPVGS 794
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+G V A ++Y I D F I TG+++ LD E+ IL +
Sbjct: 795 SVGLVQAITPANSVEV-VSYVISSGDPQGFFSIDSQTGIINTAQPLDHESISYVILNI-- 851
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
+ + D+NDN P F E
Sbjct: 852 QFHTGTLPIHSSAQVNVSITDINDNPPVFQKTSE 885
Score = 51.2 bits (117), Expect = 2e-04
Identities = 80/336 (23%), Positives = 131/336 (38%), Gaps = 40/336 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPY--HVTVDELTPTGEKAFIFLIAPI--GPSL 128
G +++ ++ + + DVNDN P F P + V + P + G +
Sbjct: 1175 GRPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNVWAVIPVNSVVISMFAKDLDAGENG 1234
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTP----NSDVHYSI-VSGNDDGHFALESSHKPVLL 183
T+ ++ I + D T N + Y++ V D+G F LE + ++
Sbjct: 1235 TVKFSMTDNQLGHFSIDSLSGDVKVTSQFSSNPQMRYTLRVVATDNGLFPLEET---AVV 1291
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVG----ATLRYELISGN 239
+V D + FQ H +L + I LGV LRY ++ GN
Sbjct: 1292 HIQVYVLDQQKENFQSSFQ------HFTVLEDVGLGTIIGSLGVSNAPDTELRYSIVEGN 1345
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
F + S +G L++ + LD + + L V+A P + +LD+
Sbjct: 1346 GSLQFGIKSSSGELYVAQHLDYEV-----TQRYFLVVRAEAF--PTFNVTVFAAVSILDV 1398
Query: 300 NDNLPEF--EVDFYNISIVENLPNGFSVLQVMATDKDQG-ENGEFTYQLD-DPKGAFS-- 353
ND+ P F + + E++ NG V A D D E Y L DP A
Sbjct: 1399 NDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAIEGL 1458
Query: 354 ---IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
IDP +G +T Q LDRE ++ +V A ++
Sbjct: 1459 PLHIDPHTGVVTTNGQ--LDRERTENIIFRVTASDS 1492
Score = 50.4 bits (115), Expect = 4e-04
Identities = 53/212 (25%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 944 IPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIV 1003
IP+ + +I + A DLD+G NG +++ ++L +F I+ G V V
Sbjct: 1214 IPVNSVVISMFAKDLDAGENGTVKFSMTD------NQLG--------HFSIDSLSGDVKV 1259
Query: 1004 AR--SLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
S P+ + L + A D G L + V + V ++ F+ ++ +F V E
Sbjct: 1260 TSQFSSNPQMRYTLRVVATDNGLFPLEETAVVHIQVYVLDQQKENFQSSFQHFTVLEDVG 1319
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++G + ++A + L Y I + L F I +G L V LD E +Y L
Sbjct: 1320 LGTIIGSLGVSNA---PDTELRYSIVEGNGSLQFGIKSSSGELYVAQHLDYEVTQRYFLV 1376
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V A DVND++P F
Sbjct: 1377 VRAE---AFPTFNVTVFAAVSILDVNDHNPWF 1405
Score = 46.8 bits (106), Expect = 0.005
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V +E+ +D + +P+F N+Y FS+ +N KVG IG + A+D D G +G+V Y L
Sbjct: 2771 VRIEIEGID--EFSPIFT-QNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSLVSP 2827
Query: 503 SNLTITSPFKINPNTGTVSVAES 525
S+ F +N G + V+ S
Sbjct: 2828 SSF-----FNVNKTNGCLFVSNS 2845
Score = 46.4 bits (105), Expect = 0.006
Identities = 51/187 (27%), Positives = 77/187 (41%), Gaps = 22/187 (11%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
HA D D G + Y L + LF++ G+L L ++ D+ ++ + L + A
Sbjct: 903 HAHDTDSGFNGRIHYMLHPKSH--LFTIHPNLGTLMLNGDVSRDS-----SSRYELSIIA 955
Query: 279 SQLNNPLKTAQARVEIEL---LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA----- 330
+P ++ + IE+ ++D L FE Y + I E+ P ++QV A
Sbjct: 956 EDEGHPSLSSTLGLVIEMDSSASVDDTLA-FETLVYQVEIGESAPKDTRMIQVRAHGNRS 1014
Query: 331 --TDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
T E TY L G F I P +GW+ V LD E S R V AK
Sbjct: 1015 QHTGTSGKETSVITYSLKPLSGVPPFRIHPETGWMFVSQS--LDYETEPSYRFCVCAKAQ 1072
Query: 387 NPSVVGT 393
N + T
Sbjct: 1073 NSKMEAT 1079
Score = 45.6 bits (103), Expect = 0.011
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--P 348
+V I++ D+NDN P F V ++++ E P G A DKD+G+ G Y++ D
Sbjct: 108 KVSIQVTDVNDNFPIFPVKIIHLNVSELSPPGTRFELEGAQDKDEGDYGTQGYRITDGEM 167
Query: 349 KGAFSIDPRSGWLTVRN-----QTVLDRE 372
+ F ++ RS + + N QT LDRE
Sbjct: 168 RELFKVEIRSNGVGMFNLDLVLQTRLDRE 196
Score = 45.6 bits (103), Expect = 0.011
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
N K A ++ +LD+NDN P F V + E+ G V VMA DKD+G NG T
Sbjct: 1497 NERKNASIIAQMIVLDINDNSPTF-VSMDIACVPEDTEVGLLVHHVMAKDKDEGRNGHVT 1555
Query: 343 YQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
Y + + K F ++ +G L + + LD E+ + V A++ PS+ T
Sbjct: 1556 YSVSSGNEKSYFHME-STGHLFLNSS--LDYESQHVHILIVQARDNGVPSLSST 1606
Score = 44.0 bits (99), Expect = 0.032
Identities = 58/226 (25%), Positives = 93/226 (41%), Gaps = 32/226 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I P GT + +A D DSG NG+I Y + P S L F I+ G
Sbjct: 889 ISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLH-----PKSHL----------FTIHPNLG 933
Query: 1000 HVIVARSLPPESEFR--LNISALDGGNLNDNISVRVFVK-----DVNDHFPVFKKTWYNF 1052
+++ + +S R L+I A D G+ + + ++ + ++ V+D F+ Y
Sbjct: 934 TLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLVIEMDSSASVDDTL-AFETLVYQV 992
Query: 1053 NVEEA--QYTRRVLGKVDA-----TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ E+ + TR + + T + + +TY ++P PF I P TG + V+
Sbjct: 993 EIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPETGWMFVS 1052
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD ETE Y V A+ D NDN+P F
Sbjct: 1053 QSLDYETEPSYRFCVCAK--AQNSKMEATATVVVMVQDENDNAPVF 1096
Score = 39.1 bits (87), Expect = 0.92
Identities = 19/47 (40%), Positives = 27/47 (57%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+V G +S+ +V +++EDVNDN PIF Y+ TV E T G
Sbjct: 527 VVASDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVG 573
Score = 36.3 bits (80), Expect = 6.5
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK 115
+ V++ + DVNDN PIF H+ V EL+P G +
Sbjct: 107 IKVSIQVTDVNDNFPIFPVKIIHLNVSELSPPGTR 141
>UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 23;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to cadherin 23 - Strongylocentrotus purpuratus
Length = 1482
Score = 130 bits (314), Expect = 3e-28
Identities = 177/735 (24%), Positives = 295/735 (40%), Gaps = 71/735 (9%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG-KVKAVDPDLGQNGMV 495
EQ+ + ++ + L D +DN P F P + ++ ++ GT + ++A D D G+ G +
Sbjct: 203 EQINTNTSIYIRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEAFDLDSGEAGRI 262
Query: 496 LYDLQRTSNLT-ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
+ L+ + + S N V V S L+ V + ++ +S+
Sbjct: 263 ILSLEDDEGIFYLVSETIFNSGVVDVRVDNSSALDFERISEVTFQIKASDAQGGNFSVVT 322
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
T+ +T + P F + Y+ + N T V Q+ DA +++++LL GY
Sbjct: 323 ATVYLTN----INDNTPVFSQSQYDVSLPENSVENTPVQQLEATDADVGAELTFELL-GY 377
Query: 615 EEGVPFAVEERSGVITVVD--DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
F + +G I+V D D + +Y V + + N TV DVND
Sbjct: 378 NNDW-FNINSSTGYISVSDTADFNAELLSVYFLTCVVSDGERVSTALLNVTV--TDVNDN 434
Query: 673 RGVLLKGAHSPII--FHV---KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ +S I ++V +E G I Q+ T+ N N++
Sbjct: 435 PPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVINRMLTYSIESGNEEGKF 494
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
D + G IF + +DRE + V+ + G S G VTI IED NDN P+F
Sbjct: 495 D--INSTTGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTTLVTISIEDVNDNNPIF 552
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
A Y + EN+ GT + I A D D + + +YT+ E F V++ G++
Sbjct: 553 LAALYNAEVPENAAFGTLVAN---ITAVDMDVDSLDV-LYTI--EEASPFLVNQE-GLIT 605
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQIEENSKVRIH 905
G ++D E ++ Y L++ A D S + +MI D ND PEF+ +S
Sbjct: 606 LSG-TVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMDVNDEPPEFDTPSPSS----- 659
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
+N +A + + P + D L + P T ++ + LD+
Sbjct: 660 --LSVNESAAY--CDSLPGS------DDCHVLITLQATDPDTNTDLRYSILDVKG----- 704
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL----- 1020
Y+ NS + + F ++ G V V L E+ R +++ +
Sbjct: 705 --YDENSRLVVG---------NFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMK 753
Query: 1021 ---DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG-KVDATDADFGQ 1076
+ D+ + + V DVND+ P F NF E V+ + A D D
Sbjct: 754 AEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAED 813
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
N + Y + D IS TG+L+V +D+E D +T A+D G
Sbjct: 814 NGIVIYELL-DDAGGLVAISETTGILTVKQPIDKELNDSLTITFCAKDGG-DPPLNTTVT 871
Query: 1137 XXXXXXDVNDNSPKF 1151
DVNDN+P F
Sbjct: 872 RQIFITDVNDNTPVF 886
Score = 100 bits (239), Expect = 4e-19
Identities = 178/735 (24%), Positives = 294/735 (40%), Gaps = 87/735 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +++ D NDNNP+F+ + LY + NA GT++ + AVD D+ VLY ++ S
Sbjct: 538 VTISIEDVNDNNPIFLAA-LYNAEVPENAAFGTLVANITAVDMDVDSLD-VLYTIEEASP 595
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT-RGT 563
+ I + GTV ++ + L V A+D+ + ++ + ++V
Sbjct: 596 FLVNQEGLITLS-GTVDYE----IQMTYNLTVTATDREDTSRQGSCTVMINIMDVNDEPP 650
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRVNDAFEQNDVSYDLLH--GYEEGV- 618
+ + P + S G + ++ D D+ Y +L GY+E
Sbjct: 651 EFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTDLRYSILDVKGYDENSR 710
Query: 619 --------PFAVEERSGVITVVDDLSRYNRPMYDFEAV-----ALQENANLSIVTNATVH 665
F V+ +G + V +L R +D V A + N + +
Sbjct: 711 LVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSAELVIT 770
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V+DVND + P F E +G + N+ + + N + D
Sbjct: 771 VLDVNDNAPEFID---LPDNFTTPETDQ---VGMVISVNILADDEDAEDNGIVIYELLDD 824
Query: 726 VTDDIAIAEDGTIFTQK-PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+AI+E I T K P+D+E D +T A+ + + I+I D NDN
Sbjct: 825 AGGLVAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTR-QIFITDVNDNT 883
Query: 785 PVFEHAT-YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
PVF + E I+E++ GT + + ATDAD L G G E F ++
Sbjct: 884 PVFNVSLPNEASILEDTTNGTLVLT---VYATDADPDFGDLTYTISAGVGLEDFVINPEN 940
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ-IEENSKV 902
G + + + LDRE++ +Y L++VA D G E+ I I D NDN PEF + E++ +
Sbjct: 941 GDIT-VQNELDREEQALYTLTVVASD-GIRQDNLEVTITILDVNDNHPEFTESFPESTTI 998
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
ET G++ I+ A+D D+ P GT + + D
Sbjct: 999 ---SETAEPGSSVAAIV--------AVDDDE--P----------GTNNSAVRYIMTDENQ 1035
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL--PPESEFRLNISAL 1020
+G + ++ + V I + S DAL + +V+ V+VA L PP N S +
Sbjct: 1036 SGFFKMDYVTGVVI-LNTTSTDAL-IPGVYVL------VVVASDLGDPPLMTDPRNFSVI 1087
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
+ ND VFV+ V+ Y+ ++ A+ T LG F
Sbjct: 1088 -VTDYND--EAPVFVQP-KQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGA 1143
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI---LTVVARDNGXXXXXXXXXXX 1137
T D F I TG + + E DRET++ YI L ++ +
Sbjct: 1144 T------DDYKYFTIDETTGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTF 1197
Query: 1138 XXXXXDVNDNSPKFY 1152
D +DN P ++
Sbjct: 1198 YVQVNDTDDNEPAYW 1212
Score = 85.4 bits (202), Expect = 1e-14
Identities = 127/514 (24%), Positives = 211/514 (41%), Gaps = 62/514 (12%)
Query: 423 DKVGTKTENIEYYDEQLMSF--VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
+++ T I+ D Q +F V V L + NDN PVF S Y+ S+ N+ T +
Sbjct: 299 ERISEVTFQIKASDAQGGNFSVVTATVYLTNINDNTPVFSQSQ-YDVSLPENSVENTPVQ 357
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD 540
+++A D D+G + ++L +N F IN +TG +SV+++ L V
Sbjct: 358 QLEATDADVGAE--LTFELLGYNN----DWFNINSSTGYISVSDTADFNAE-LLSVYFLT 410
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKP----DIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
+ ER S A++ + VT N P D+ Y + G ++ Q+
Sbjct: 411 CVVSDGER-VSTALLNVTVT-DVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVL 468
Query: 597 VNDA---FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN 653
DA ++Y + G EEG F + +G+I + R FE V + +
Sbjct: 469 ATDADINVINRMLTYSIESGNEEG-KFDINSTTGMIFRKASIDRETEEA-TFEMVVMAID 526
Query: 654 A---NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIY 709
+++ T T+ + DVND + L ++ V EN+A G + I +M
Sbjct: 527 GGTPSMNGTTLVTISIEDVNDNNPIFLAALYNA---EVPENAAFGTLVANITAVDMDV-- 581
Query: 710 GNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG 769
+ +V + I + + ++G I +D E + Y +TV A + S G
Sbjct: 582 --DSLDVLYTI----EEASPFLVNQEGLITLSGTVDYEIQMTYNLTVTATDREDT-SRQG 634
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKI-------GTEIKMDNIIKATDADEGTN 822
V I I D ND PP F+ + + S + + ++ATD D T+
Sbjct: 635 SCTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTD 694
Query: 823 ALFMYT-----------LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+ + G + F VD TG V F+ LDRE + +++V D
Sbjct: 695 LRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDV-FVRTELDRETVQRFDVTVVVDDMK 753
Query: 872 G------LSSEAELIIMIGDENDNKPEFNQIEEN 899
+ AEL+I + D NDN PEF + +N
Sbjct: 754 AEENNDTQTDSAELVITVLDVNDNAPEFIDLPDN 787
Score = 81.0 bits (191), Expect = 2e-13
Identities = 171/733 (23%), Positives = 280/733 (38%), Gaps = 72/733 (9%)
Query: 374 HSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIE 433
+S L +K Y E + VVG F+D + +T F V E
Sbjct: 697 YSILDVKGY-DENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAE 755
Query: 434 YYDEQLMSFVNVEVTLLDANDNNPVFV--PSNLYEFSMKSNAKVGTVIG-KVKAVDPDLG 490
++ + +T+LD NDN P F+ P N F+ +VG VI + A D D
Sbjct: 756 ENNDTQTDSAELVITVLDVNDNAPEFIDLPDN---FTTPETDQVGMVISVNILADDEDAE 812
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVE--ASDQPANPSER 548
NG+V+Y+L + + I+ TG ++V + E +L + A D P
Sbjct: 813 DNGIVIYELLDDAGGLVA----ISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNT 868
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDF-MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-NDV 606
+ + +V T P F + P E + + GT V + DA D+
Sbjct: 869 TVTRQIFITDVNDNT-------PVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDL 921
Query: 607 SYDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQ--ENANLSIVTNAT 663
+Y + G G+ F + +G ITV ++L R + +Y VA NL + T
Sbjct: 922 TYTISAGV--GLEDFVINPENGDITVQNELDREEQALYTLTVVASDGIRQDNLEV----T 975
Query: 664 VHVVDVNDERGVLLKG-AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ ++DVND + S I E G+++ I + G VR+++ +
Sbjct: 976 ITILDVNDNHPEFTESFPESTTISETAE--PGSSVAAIVAVDDDEP-GTNNSAVRYIMTD 1032
Query: 723 Q-QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ Q + I D VY + V+A ++ + D N
Sbjct: 1033 ENQSGFFKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYN 1092
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGK----EM 836
D PVF + + I +ATD D G N + + G G +
Sbjct: 1093 DEAPVFVQPKQGATVYVDENYSGHI---TTAEATDGDLGDNGVVTFAFDTGLGATDDYKY 1149
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F +DE TG ++ ++ DRE K +Y L+ G++++++ I + + N
Sbjct: 1150 FTIDETTGAIEITSET-DRETKEIYIRLLLG--IIGMNAKSDPIR--SSQVTFYVQVNDT 1204
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKL-NA 955
++N T G + P+ L + EN+ GT + + A
Sbjct: 1205 DDNEPAYWGERTGPEGP------QDPPE----------AALLYVQENLGEGTFVGTVPEA 1248
Query: 956 LDLDSGLNGQIRY---EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
+DLDS L QI Y SE Y K S + V +++ P+ E
Sbjct: 1249 VDLDSDLYNQIYYFIVSATSEDYFILDKYSGNLTLVNPIDREKRPEFSLVIWADSNPDYE 1308
Query: 1013 FRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+N+ + DN++ V V V DVND P F++ Y V + + V+A D
Sbjct: 1309 PDMNV--IYDPLKEDNLARVTVTVSDVNDSPPRFEEDRYTAGVLYSTSFGVEVITVNAVD 1366
Query: 1072 ADFGQNANLTYFI 1084
D G+NA Y I
Sbjct: 1367 PDLGENAVTVYTI 1379
Score = 75.4 bits (177), Expect = 1e-11
Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 7/167 (4%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
L+ GN F +DS G +F+ ELD + V ++A + NN +T A + I
Sbjct: 711 LVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEE-NNDTQTDSAELVI 769
Query: 295 ELLDLNDNLPEFEVDF-YNISIVENLPNGFSV-LQVMATDKDQGENGEFTYQ-LDDPKGA 351
+LD+NDN PEF +D N + E G + + ++A D+D +NG Y+ LDD G
Sbjct: 770 TVLDVNDNAPEF-IDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYELLDDAGGL 828
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
+I +G LTV+ +D+E + SL + AK+ + T Q
Sbjct: 829 VAISETTGILTVKQP--IDKELNDSLTITFCAKDGGDPPLNTTVTRQ 873
Score = 68.5 bits (160), Expect = 1e-09
Identities = 107/423 (25%), Positives = 176/423 (41%), Gaps = 55/423 (13%)
Query: 991 YFVINERHGHVIVARSLPPESE----FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
+F IN G++ V+ + +E + L DG ++ + + V V DVND+ P+F+
Sbjct: 381 WFNINSSTGYISVSDTADFNAELLSVYFLTCVVSDGERVSTAL-LNVTVTDVNDNPPLFQ 439
Query: 1047 KTWYN-----FNVEEAQYTRRVLG--KVDATDADFGQ-NANLTYFIQPSDTDLPFEISPL 1098
Y+ +NV+ + L +V ATDAD N LTY I+ + + F+I+
Sbjct: 440 LDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVINRMLTYSIESGNEEGKFDINST 499
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
TG++ +DRETE+ VV +G DVNDN+P F A L
Sbjct: 500 TGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTTLVTISIEDVNDNNPIFLA--ALY 557
Query: 1159 EWKHPEADELSNHNFES-VMMIPVYKATIEENAPIGT-TVAKVFANDTDFIGNGNGLILY 1216
+ PE N F + V I ++ + T A F + + + +G + Y
Sbjct: 558 NAEVPE-----NAAFGTLVANITAVDMDVDSLDVLYTIEEASPFLVNQEGLITLSGTVDY 612
Query: 1217 SLPQRKNQQNLGL----PSLSSTAILMVTVADVPDEVEMSDKP------VFISRYYELEI 1266
+ N S + +M+ + DV DE D P V S Y +
Sbjct: 613 EIQMTYNLTVTATDREDTSRQGSCTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSL 672
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRYYIL-----NENDT----DIRRTFVIDPRNGTLYL 1317
+ + V L++L T+ N +RY IL +EN + F +D G +++
Sbjct: 673 PGSDDCHV-LITLQATDPDTNTDLRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDVFV 731
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
DRE ++V V + K AE+ + T ++V+ + DVNDN+
Sbjct: 732 RTELDRETVQRFDVTVVVDDMK------------AEENNDTQTD-SAELVITVLDVNDNA 778
Query: 1378 PKF 1380
P+F
Sbjct: 779 PEF 781
Score = 64.1 bits (149), Expect = 3e-08
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 12/171 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+D + YEL+ + L ++ G L +++ +D + +L TF +
Sbjct: 804 ILADDEDAEDNGIVIYELLD-DAGGLVAISETTGILTVKQPIDKELNDSLTI-TFCAKDG 861
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQG 336
PL T R +I + D+NDN P F V N SI+E+ NG VL V ATD D
Sbjct: 862 GDP---PLNTTVTR-QIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADP- 916
Query: 337 ENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ G+ TY + G F I+P +G +TV+N+ LDRE + + V A +
Sbjct: 917 DFGDLTYTISAGVGLEDFVINPENGDITVQNE--LDREEQALYTLTVVASD 965
Score = 61.7 bits (143), Expect = 2e-07
Identities = 67/266 (25%), Positives = 109/266 (40%), Gaps = 18/266 (6%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDE--LTPTGEKAFIFLIAPIGPSLTIPLTVPRGL 138
++ TVY+ ++NDN P+F + Y V++ E + T + A +G LT L
Sbjct: 321 VTATVYLTNINDNTPVFSQSQYDVSLPENSVENTPVQQLEATDADVGAELTFELLGYNN- 379
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-KVLDYDAGDKEF 197
+ +I + + +D + ++S + LL V D + F
Sbjct: 380 -DWFNINSSTGYISVSDTADFNAELLSVYFLTCVVSDGERVSTALLNVTVTDVNDNPPLF 438
Query: 198 QLVIMA-SGKRIHKEILFPEP-------IHAIDQDLGV-GATLRYELISGNDRKLFSLDS 248
QL + + S + ++L E + A D D+ V L Y + SGN+ F ++S
Sbjct: 439 QLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVINRMLTYSIESGNEEGKFDINS 498
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
G +F + +D + E TF + V A P V I + D+NDN P F
Sbjct: 499 TTGMIFRKASIDRETEEA----TFEMVVMAIDGGTPSMNGTTLVTISIEDVNDNNPIFLA 554
Query: 309 DFYNISIVENLPNGFSVLQVMATDKD 334
YN + EN G V + A D D
Sbjct: 555 ALYNAEVPENAAFGTLVANITAVDMD 580
Score = 60.9 bits (141), Expect = 3e-07
Identities = 55/190 (28%), Positives = 99/190 (52%), Gaps = 22/190 (11%)
Query: 217 PIHAIDQ-DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
P+ ++ D VGA L +EL+ G + F+++S G + + D +AE L + F+
Sbjct: 355 PVQQLEATDADVGAELTFELL-GYNNDWFNINSSTGYISVSDTADFNAE--LLSVYFLTC 411
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI-------VENLPNGFSVLQV 328
V +++ + + A + + + D+NDN P F++D Y++SI +E G ++LQV
Sbjct: 412 V----VSDGERVSTALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQV 467
Query: 329 MATDKDQGE-NGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREA-HSSLRMKVYAK 384
+ATD D N TY ++ + +G F I+ +G + + +DRE ++ M V A
Sbjct: 468 LATDADINVINRMLTYSIESGNEEGKFDINSTTG--MIFRKASIDRETEEATFEMVVMAI 525
Query: 385 E-TNPSVVGT 393
+ PS+ GT
Sbjct: 526 DGGTPSMNGT 535
Score = 60.9 bits (141), Expect = 3e-07
Identities = 153/633 (24%), Positives = 247/633 (39%), Gaps = 85/633 (13%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L + V ++ + D NDN PVF S E S+ + GT++ V A D D G +
Sbjct: 863 DPPLNTTVTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDAD-PDFGDL 921
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y + L F INP G ++V E + + L V ASD R+ +L
Sbjct: 922 TYTISAGVGL---EDFVINPENGDITVQNELDREEQALYTLTVVASD-----GIRQDNLE 973
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE----QNDVSYD 609
VTI + N P+ + P + G+SV I D E + V Y
Sbjct: 974 -VTITIL-DVNDNHPEFTE--SFPESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYI 1029
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRP-MYDFEAVA--LQENANLSIVTNATVHV 666
+ + G F ++ +GV+ + + P +Y VA L + ++ N +V V
Sbjct: 1030 MTDENQSGF-FKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRNFSVIV 1088
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D NDE V ++ ++ V EN + G I + G V F
Sbjct: 1089 TDYNDEAPVFVQPKQGATVY-VDENYS----GHITTAEATDGDLGDNGVVTFAFDTGLGA 1143
Query: 727 TDD---IAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIE--D 779
TDD I E G I DRE +++Y ++ S QVT Y++ D
Sbjct: 1144 TDDYKYFTIDETTGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVND 1203
Query: 780 ENDNPPVF--EHATYEG----------FIMENSKIGTEIKMDNIIKATDADEGT-NALFM 826
+DN P + E EG ++ EN GT + + +A D D N ++
Sbjct: 1204 TDDNEPAYWGERTGPEGPQDPPEAALLYVQENLGEGTFV--GTVPEAVDLDSDLYNQIYY 1261
Query: 827 YTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDE 886
+ + ++ F +D+ +G + + + +DREK+ E L+I
Sbjct: 1262 FIVSATSEDYFILDKYSGNLTLV-NPIDREKR----------------PEFSLVIWADSN 1304
Query: 887 NDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI 946
D +P+ N I + K + T + + P +F D G L+ +
Sbjct: 1305 PDYEPDMNVIYDPLK----EDNLARVTVTVSDVNDSPP-RFEEDRYTAGVLY----STSF 1355
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI--VA 1004
G +I +NA+D D G N Y S+ ++V F IN+ G VI V
Sbjct: 1356 GVEVITVNAVDPDLGENAVTVYTILSQKSYDADGNGGVEVDV---FAIND--GKVINSVT 1410
Query: 1005 RSLPPESEFRLNISALDGGNLN--DNISVRVFV 1035
+S + + + A D N N DN ++ V++
Sbjct: 1411 FQASDDSYYIVELQATDSLNPNFTDNATLSVYL 1443
Score = 59.7 bits (138), Expect = 6e-07
Identities = 93/374 (24%), Positives = 147/374 (39%), Gaps = 58/374 (15%)
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSP 1149
F + TG + V ELDRET ++ +TVV D DVNDN+P
Sbjct: 720 FGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSAELVITVLDVNDNAP 779
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---F 1206
+F + + PE D++ M+I V +E+A V +D
Sbjct: 780 EFIDLPD--NFTTPETDQVG-------MVISVNILADDEDAEDNGIVIYELLDDAGGLVA 830
Query: 1207 IGNGNGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
I G++ P K + G P L++T + + DV D PV
Sbjct: 831 ISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFITDVNDNT-----PV 885
Query: 1257 F-ISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
F +S E I E+ ++++ T+ +F Y ++ FVI+P NG +
Sbjct: 886 FNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTISAGVG--LEDFVINPENGDI 943
Query: 1316 YLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVND 1375
+ DRE + Y + V VA D G+ + +++V + I DVND
Sbjct: 944 TVQNELDREEQALYTLTV-----------------VASD---GIRQDNLEVTITILDVND 983
Query: 1376 NSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHP----TASRTVRADTDELVFFERL 1431
N P+FT + P T I TA G V + P +A R + D ++ FF+
Sbjct: 984 NHPEFTE-SFPESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFKMD 1042
Query: 1432 SLNGLTSPQATDSD 1445
+ G+ T +D
Sbjct: 1043 YVTGVVILNTTSTD 1056
Score = 55.2 bits (127), Expect = 1e-05
Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-----L 274
A+D D + + Y ++S F LD +G+L L +D + +
Sbjct: 1248 AVDLDSDLYNQIYYFIVSATSEDYFILDKYSGNLTLVNPIDREKRPEFSLVIWADSNPDY 1307
Query: 275 QVQASQLNNPLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ + + +PLK ARV + + D+ND+ P FE D Y ++ + G V+ V A D
Sbjct: 1308 EPDMNVIYDPLKEDNLARVTVTVSDVNDSPPRFEEDRYTAGVLYSTSFGVEVITVNAVDP 1367
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSG 359
D GEN Y + K ++ D G
Sbjct: 1368 DLGENAVTVYTILSQK-SYDADGNGG 1392
Score = 50.4 bits (115), Expect = 4e-04
Identities = 78/306 (25%), Positives = 119/306 (38%), Gaps = 29/306 (9%)
Query: 85 VYIEDVNDNVPIF-LDTPYHVTVDELTPTGEKAFIFLIAPIGPS---LTIPLTVPRGLTI 140
++I DVNDN P+F + P ++ E T G P LT ++ GL
Sbjct: 874 IFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTISAGVGLED 933
Query: 141 FK-DIRAFDRDKPNTPNSDVH--YSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
F + D N + + Y++ DG + + V + +LD + EF
Sbjct: 934 FVINPENGDITVQNELDREEQALYTLTVVASDG---IRQDNLEVTIT--ILDVNDNHPEF 988
Query: 198 QLVIMASG--KRIHKEILFPEPIHAIDQDL-GVG-ATLRYELISGNDRKLFSLDSVNGSL 253
S + I A+D D G + +RY + N F +D V G +
Sbjct: 989 TESFPESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFKMDYVTGVV 1048
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYN 312
L DA L +VL V AS L +P L T + + D ND P F
Sbjct: 1049 ILNTT-STDA---LIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEAPVFVQPKQG 1104
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA------FSIDPRSGWLTVRNQ 366
++ + + ATD D G+NG T+ D GA F+ID +G + + ++
Sbjct: 1105 ATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGATDDYKYFTIDETTGAIEITSE 1164
Query: 367 TVLDRE 372
T DRE
Sbjct: 1165 T--DRE 1168
Score = 41.1 bits (92), Expect = 0.23
Identities = 39/153 (25%), Positives = 71/153 (46%), Gaps = 7/153 (4%)
Query: 224 DLGVGATLRYELISGNDRKLFSL--DSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQ 280
DL G R L +D +F L +++ S ++ +D + + + + V Q++AS
Sbjct: 253 DLDSGEAGRIILSLEDDEGIFYLVSETIFNSGVVDVRVDNSSALDFERISEVTFQIKASD 312
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ + L ++NDN P F Y++S+ EN V Q+ ATD D G E
Sbjct: 313 AQGG-NFSVVTATVYLTNINDNTPVFSQSQYDVSLPENSVENTPVQQLEATDADVG--AE 369
Query: 341 FTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
T++ L F+I+ +G+++V + + E
Sbjct: 370 LTFELLGYNNDWFNINSSTGYISVSDTADFNAE 402
Score = 41.1 bits (92), Expect = 0.23
Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 13/112 (11%)
Query: 1292 YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE-RQKYSRELPHMIYP 1350
Y+I++ D F++D +G L LV DRE + + +++ A+ Y ++ + P
Sbjct: 1261 YFIVSATSEDY---FILDKYSGNLTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDP 1317
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVM 1402
+ ED L +V V + DVND+ P+F +R + +T+ FG +V+
Sbjct: 1318 LKEDNL-------ARVTVTVSDVNDSPPRFEE-DRYTAGVLYSTS-FGVEVI 1360
Score = 39.5 bits (88), Expect = 0.69
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 292 VEIELLDLNDNLPEFEVD-FYNISIVENLPNGFSV-LQVMATDKDQGENGEFTYQLDDPK 349
+ I L D++DN P F N +I E+ P G + + A D D GE G L+D +
Sbjct: 211 IYIRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEAFDLDSGEAGRIILSLEDDE 270
Query: 350 GAFSIDP----RSGWLTVR--NQTVLDREAHSSLRMKVYAKE 385
G F + SG + VR N + LD E S + ++ A +
Sbjct: 271 GIFYLVSETIFNSGVVDVRVDNSSALDFERISEVTFQIKASD 312
Score = 35.9 bits (79), Expect = 8.6
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE 108
++ I G ++ VT+ IEDVNDN PIFL Y+ V E
Sbjct: 522 VMAIDGGTPSMNGTTLVTISIEDVNDNNPIFLAALYNAEVPE 563
>UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 3766
Score = 130 bits (313), Expect = 4e-28
Identities = 190/779 (24%), Positives = 323/779 (41%), Gaps = 107/779 (13%)
Query: 408 LETNAPLEKTTYVFPDKV--GTKTENIEYYDEQ----LMSFVNVEVTLLDANDNNPVFVP 461
+ETN ++ + + +++ G KT ++ ++ L S +V +TL D ND+ P F
Sbjct: 1765 VETNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYSTCSVAITLEDVNDDKPTFDL 1824
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS 521
N Y+ ++ NA +GT + +KA D D G G+V Y L+ S+ F I+ N+GT++
Sbjct: 1825 GN-YDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSD----EHFAIDVNSGTLT 1879
Query: 522 VAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE 579
+S EG+ ++ V A D+ NP +AV + V + + P P F A ++
Sbjct: 1880 TKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVD---ENDSP--PQFDQAEFQ 1934
Query: 580 FWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-LLHGYEEGVPFAVEERS------GVITVV 632
V + IGTS+ ++ D ++ + + G + FAV+ S G + V
Sbjct: 1935 TSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKSGRTYGEVQVD 1994
Query: 633 DDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH----SPIIF-H 687
L + Y + A + S T + + D ND + + SPI
Sbjct: 1995 ARLDFETKSSYTIDVTAT--DGRFSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGR 2052
Query: 688 VKE-NSAGAAIGQIFHTNMSSI---YGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP 743
V E +G + +++ + S Y + F IA +Q+ + I G+ +P
Sbjct: 2053 VSEMTGSGVEVLKVYAVDTDSPNIQYTLEGSSSYFTIAARQEGGKFVGIISTGS----QP 2108
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE ++ V+A+ GV +G+ ++ + D NDN P F ++ Y G++ EN G
Sbjct: 2109 LDREATPIFSFNVLAK--DGVHTGSAYIEINV--TDINDNQPRFPNSLYVGYVEENKAAG 2164
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T + ++A D D+ L G + + + +N G KF +D ++
Sbjct: 2165 TSVMY---VQAHDDDDPY-------LGGNAEIRYTLTDNAGG-KF---KIDANTALVTTE 2210
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
++ R+T + + ++ D+ NK +KV T N A V
Sbjct: 2211 EILDRETS--PNSFTITVLATDQGANKLS------TTKVATIYVTDANDHA-----PVFT 2257
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN-----SEVYIPP 978
K F V E++ G + ++A D D+G N ++ + + Y+ P
Sbjct: 2258 KRIFRGTVS---------EDVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDP 2308
Query: 979 SKLSADALEVKRYFVINERHGHVIVA-RSLPPESEFRLNISALDGGNLNDNISVRVFVKD 1037
SK + + Y + + V V+ R +P S+ N V + + D
Sbjct: 2309 SKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSD-------------NSPAYVLITITD 2355
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ P+F YN V E + V A D D G NA + I + D FE+ P
Sbjct: 2356 ANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVP 2415
Query: 1098 -----LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
G++ LDRET + L + A+D G DVNDN P F
Sbjct: 2416 NPDNSSLGIVRTRLPLDRETTPIHHLEITAKDTG---GLTGKAHVWLTLLDVNDNGPWF 2471
Score = 101 bits (242), Expect = 2e-19
Identities = 114/436 (26%), Positives = 182/436 (41%), Gaps = 41/436 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLY-EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L + V VT+ D NDN P+F + +F + + A T+I ++AVD D G N V
Sbjct: 1084 LATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTM 1143
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+Q T + +PF I+ + + + + V A+D+ + P +YS V +
Sbjct: 1144 SIQGT--VPSNAPFTIDTPSNVLKTTTKLSTVIDYQITVRATDKGSPP---QYSETTVIV 1198
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+V N P F A Y V N +G V ++ + Y + G G
Sbjct: 1199 KVL-----NIQTPPVFGQAKYTVDVQENTKVGQQVISVKATYGDSNALLQYSFVSG-NLG 1252
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVL 676
F ++ SG ITV L R P Y VAL N + T V + D+ND+
Sbjct: 1253 DAFCIDS-SGQITVAQPLDREVLPSYTLRVRVALGNNEDF---TEVVVSLTDINDDSPTF 1308
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K + F ++ S+G +IG++ T+ S +G + RFL A+ D + +
Sbjct: 1309 TKSVYE--FFANEDISSGTSIGKVAATDRDS-GSHGQISYRFLYASDIQSMDKFDLDQTT 1365
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I + L K Y IAE V IY+ D NDN P F A+Y +
Sbjct: 1366 GIIS---LASGKSLDYEDITIAE-------------VRIYLRDINDNDPKFSAASYHAKL 1409
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDR 855
++ + + + ATD D N Y++ +E F V + G+++ + SL
Sbjct: 1410 SLDAPVLEHVVQ---VTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIR-VAKSLTT 1465
Query: 856 EKKIMYKLSLVARDTG 871
+ L+L A D+G
Sbjct: 1466 VAASSFLLTLEAADSG 1481
Score = 87.4 bits (207), Expect = 3e-15
Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 22/206 (10%)
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRD----VYRMTVIA-EFNKGVISGAGIYQVTIYIED 779
D+ + ++ +G I T LD E+ +++ V A E N + S V I +ED
Sbjct: 1758 DIDEKFSVETNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYSTCS---VAITLED 1814
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
ND+ P F+ Y+ + EN+ IGT + IKATD D G + Y L E F +
Sbjct: 1815 VNDDKPTFDLGNYDARVRENAPIGTTVIT---IKATDRDTGDAGVVTYFLKAGSDEHFAI 1871
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGG----LSSEAELIIMIGDENDNKPEFNQ 895
D N+G + S DRE + ++ + ++ARD G LS E + +++ DEND+ P+F+Q
Sbjct: 1872 DVNSGTLT-TKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQ 1930
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEV 921
E + V + T G +I+EV
Sbjct: 1931 AEFQTSV------SESATIGTSILEV 1950
Score = 81.8 bits (193), Expect = 1e-13
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 48/278 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN PIGTT+I + A D D+G G + Y K +D +F I+ G
Sbjct: 1831 VRENAPIGTTVITIKATDRDTGDAGVVTYFL---------KAGSD-----EHFAIDVNSG 1876
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN----LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ +S E + F + + A D GN L++ ++V+V V D ND P F + + +
Sbjct: 1877 TLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTS 1936
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT------GVLSVNGE 1107
V E+ + +V ATD D G NA L YFI D F + ++ G + V+
Sbjct: 1937 VSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQTISKSGRTYGEVQVDAR 1996
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LD ET+ Y + V A D D ND P F
Sbjct: 1997 LDFETKSSYTIDVTATDG----RFSATTRVLITITDANDIVPMFMTLT------------ 2040
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
++ P+Y + E G V KV+A DTD
Sbjct: 2041 ------TPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD 2072
Score = 78.6 bits (185), Expect = 1e-12
Identities = 114/483 (23%), Positives = 200/483 (41%), Gaps = 53/483 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV-KAVDPDLGQNGMVLYDLQRTS 503
+ +T+ D N+ P F ++ Y + A GT +G + K D ++G+ Y++ +
Sbjct: 118 LRITVTDTNNFQPTF-GADFYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRYEIVSGN 176
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS-----LAVVTIE 558
T TV + +L+ + V +P+ R + I+
Sbjct: 177 ERGY-----FVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGGLHGTTRIQ 231
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEG 617
+ N P P F + Y VG + + TS+ ++R DA +N Y L ++
Sbjct: 232 IDIQDTNNNP--PVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYYYLRNTQD- 288
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG--- 674
F ++ +GVI + L + E A ++ + N V V +D G
Sbjct: 289 --FTIDAITGVIRPIRMLDFQSGQQRTLEVTA-RDRGSSPKAANVNVQVTIRSDISGYPP 345
Query: 675 VLLKGAHS----PIIF--------HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V++ + S P +F ++E+ Q+ N G+ G +R+ ++
Sbjct: 346 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDA-GSTNGQLRYSLSG 404
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDRE---KRDVYRMTVIAEFNKGVISGAGIYQVTIYIE- 778
+ D + G + Q L+ + +DV + V A G SGA V + IE
Sbjct: 405 NNNFAID---STSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQ-SGALSASVNLKIEV 460
Query: 779 ---DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGK 834
D+N+N PVF E + E+S +G I+ + ATD+D+G++ +Y++ G G
Sbjct: 461 LDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRR---VSATDSDDGSDGQVVYSIIQGSGL 517
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM--IGDENDNKPE 892
+F V TG + + LDREK Y L + A D + L +M I D +D+ P+
Sbjct: 518 GVFQVQATTGDL-IVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDHFPQ 576
Query: 893 FNQ 895
F Q
Sbjct: 577 FTQ 579
Score = 78.2 bits (184), Expect = 2e-12
Identities = 112/464 (24%), Positives = 193/464 (41%), Gaps = 50/464 (10%)
Query: 452 ANDNN--PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ-NGMVLYDLQRTSNLTIT 508
++D N PVF + + S++ + V I VKA DPD G NG + Y L +N
Sbjct: 352 SSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGNNN---- 407
Query: 509 SPFKINPNTGTVSVAESPILEGRHA-----LFVEASDQPANPSERRYSLAV-VTIEVTRG 562
F I+ +G V++ +G A L V A+D+ N S +V + IEV
Sbjct: 408 --FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDR--NGQSGALSASVNLKIEVLDV 463
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPF 620
N + P F E V + +G ++ ++ D+ + +D V Y ++ G GV F
Sbjct: 464 DDNN--NAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGSGLGV-F 520
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN--ATVHVVDVNDERGVLLK 678
V+ +G + V L R YD + ++ A +N V + DV+D +
Sbjct: 521 QVQATTGDLIVAAPLDREKMSFYDL-VIKAEDKATFPKSSNLYVMVKIQDVDDHFPQFTQ 579
Query: 679 GAH-SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ + EN+ + + H S+ + TG F I + G
Sbjct: 580 PMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASSFKI-----------VPTSGL 628
Query: 738 IFTQKPLD-REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I T P+D + Y + V A + QV + I + ++PPVF++ Y +
Sbjct: 629 ILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAVSV 688
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN + + N++ D + +Y++ G E F +D +G + S D E
Sbjct: 689 PEN-----QGSIANLVCVAAIDTKGQPV-IYSIESRG-EPFGIDSKSGRFSSL-QSFDYE 740
Query: 857 KKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQIE 897
Y++ + A+ ++S +++ I I DE D P+F+Q E
Sbjct: 741 TADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSE 783
Score = 77.4 bits (182), Expect = 3e-12
Identities = 110/476 (23%), Positives = 192/476 (40%), Gaps = 72/476 (15%)
Query: 940 IPENIPIGTTIIKLNALDL-DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
I E GTT+ L D +G RYE S + +++ V+ +
Sbjct: 141 IAEEAAQGTTVGGLEKCHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATN 200
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
++ R P L + A DGG L+ +++ ++D N++ PVF+K+ Y V E
Sbjct: 201 TRIV--RD-PARPSITLTVRANDGGGLHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDT 257
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
+ +V A DAD G+N + Y+++ + F I +TGV+ LD ++ + L
Sbjct: 258 PVMTSILRVRARDADIGRNGGIYYYLRNTQ---DFTIDAITGVIRPIRMLDFQSGQQRTL 314
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
V ARD G D++ P + P E S+
Sbjct: 315 EVTARDRGSSPKAANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSS-------- 366
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN---QQNLGLPSLSS- 1234
+ +I E+ P+ + V AND D G+ NG + YSL N G+ +L +
Sbjct: 367 ---FTLSIREDFPVNGAIQVVKANDPD-AGSTNGQLRYSLSGNNNFAIDSTSGVVTLQTQ 422
Query: 1235 ----------TAILMVTVAD-----------VPDEVEMSD------KPVFISRYYELEIE 1267
L+VT D V ++E+ D PVF + EL +
Sbjct: 423 LEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVS 482
Query: 1268 EN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
E+ V + VS ++ + ++ Y I+ + + F + G L + DRE
Sbjct: 483 EDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGSGLGV---FQVQATTGDLIVAAPLDREK 539
Query: 1326 KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
Y+++++AE + +P + ++ V+V+I+DV+D+ P+FT
Sbjct: 540 MSFYDLVIKAEDK--------ATFPKSSNLY---------VMVKIQDVDDHFPQFT 578
Score = 73.7 bits (173), Expect = 3e-11
Identities = 57/170 (33%), Positives = 88/170 (51%), Gaps = 12/170 (7%)
Query: 228 GATLRYELISGN---DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
G ++ Y + N D K FS+++ NG + +LD + + + TF LQV+A + N
Sbjct: 1745 GKSIVYSPVKANADIDEK-FSVET-NGQIKTASQLDYE-QLSPGDKTFKLQVRAQEENTN 1801
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
L + V I L D+ND+ P F++ Y+ + EN P G +V+ + ATD+D G+ G TY
Sbjct: 1802 LYST-CSVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYF 1860
Query: 345 LDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE--TNPSVV 391
L F+ID SG LT + DRE S + V A++ NP +
Sbjct: 1861 LKAGSDEHFAIDVNSGTLTTKKS--FDREGQSLFSVIVIARDKGNNPGAL 1908
Score = 70.1 bits (164), Expect = 4e-10
Identities = 104/469 (22%), Positives = 185/469 (39%), Gaps = 39/469 (8%)
Query: 439 LMSFVNVEVTLLDANDNN--PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
L + VN+++ +LD +DNN PVF P L E ++ ++ VG I +V A D D G +G V+
Sbjct: 450 LSASVNLKIEVLDVDDNNNAPVFNPQQL-ELTVSEDSAVGRTIRRVSATDSDDGSDGQVV 508
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLA 553
Y + + S L + F++ TG + VA +P+ + + L ++A D+ P +
Sbjct: 509 YSIIQGSGLGV---FQVQATTGDLIVA-APLDREKMSFYDLVIKAEDKATFPKSSNLYVM 564
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V +V P F Y T V ++V D VSY +
Sbjct: 565 VKIQDV-------DDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGA 617
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDE 672
F + SG+I + P +E V + N AT V V++ +
Sbjct: 618 SS----FKIVPTSGLILTTGPIDLTTEPS-TYELVVTATSTNYGTTKRATGQVNVEITSK 672
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
++P V EN A N+ + T + + +
Sbjct: 673 TESPPVFKNTPYAVSVPENQGSIA-------NLVCVAAIDTKGQPVIYSIESRGEPFGID 725
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++ G + + D E D YR+ + A+ V I I+DE D PP F + Y
Sbjct: 726 SKSGRFSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEY 784
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNAL--FMYTLFGE-GKEMFDVDENTGVVKF- 848
+ + E + + + + I+ D D + L M + + V ++ G KF
Sbjct: 785 KVSVPEGASVRSTLSRG--IRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGGECKFV 842
Query: 849 IGDSLDR--EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
I +LD K + + + ++ G+ + ++ + + D N P F++
Sbjct: 843 IEKTLDTFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPVFSR 891
Score = 67.7 bits (158), Expect = 2e-09
Identities = 102/446 (22%), Positives = 194/446 (43%), Gaps = 59/446 (13%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
PVF + Y ++ N KVG + VKA D N ++ Y + NL F I+ +
Sbjct: 1207 PVFGQAK-YTVDVQENTKVGQQVISVKATYGD--SNALLQYSFV-SGNLG--DAFCID-S 1259
Query: 517 TGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGA 576
+G ++VA+ E + + N + ++ VV++ T N D P F +
Sbjct: 1260 SGQITVAQPLDREVLPSYTLRVRVALGNNED--FTEVVVSL-----TDIND-DSPTFTKS 1311
Query: 577 PYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHG--YEEGVPFAVEERSGVITVV 632
YEF+ ++ GTS+G++ D + +SY L+ + F +++ +G+I++
Sbjct: 1312 VYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLA 1371
Query: 633 DDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
S D+E + + E +++ D+ND S +H K +
Sbjct: 1372 SGKS------LDYEDITIAE---------VRIYLRDINDN-----DPKFSAASYHAKLSL 1411
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDV 751
+ + + + G +R+ ++A Q+ + + ++G I K L
Sbjct: 1412 DAPVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQV-LTDNGLIRVAKSLTTVAASS 1470
Query: 752 YRMTV-IAEFNKGVISGAGIYQVTIYIEDENDN---PPVFEHATYEGFIMENSKIGTEIK 807
+ +T+ A+ G+ QV +++ D PV +AT EG I N ++
Sbjct: 1471 FLLTLEAADSGDPERKGSVNVQVNVFLPDGPPKFVLDPVIVNAT-EG-IAANQRVA---- 1524
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
+ KA ++ AL L G +MF ++ ++GV+ + LD E+ Y ++++A
Sbjct: 1525 ---VAKAATSE----ALKYEILSGNTNDMFAINPSSGVILTTRE-LDYEEATGYIMNIIA 1576
Query: 868 RDTGGLSSEAELIIMIGDENDNKPEF 893
RDT S+ ++II + + NDN+P F
Sbjct: 1577 RDTRDRSASVQVIINVVNINDNEPMF 1602
Score = 67.7 bits (158), Expect = 2e-09
Identities = 52/176 (29%), Positives = 85/176 (48%), Gaps = 12/176 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A L + + GN+ F +D G++ + L+ + L+ ++ L V
Sbjct: 2278 VSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGILN----YTLR-KSYNLTVT 2332
Query: 278 ASQLNNPLKT--AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
S P+ + + A V I + D NDN P F + YN ++ E+L G V+ V A D D
Sbjct: 2333 VSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDS 2392
Query: 336 GENGEFTYQL--DDPKGAFSIDP---RSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
G+N +F + + +P F + P S VR + LDRE +++ AK+T
Sbjct: 2393 GDNAKFVFDITGGNPDDLFEVVPNPDNSSLGIVRTRLPLDRETTPIHHLEITAKDT 2448
Score = 66.9 bits (156), Expect = 4e-09
Identities = 104/458 (22%), Positives = 185/458 (40%), Gaps = 64/458 (13%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
P+ +P T++++L +D D G G++ Y+ I P+ + + R+ V + G
Sbjct: 899 PDTLPTDTSVMQLPIIDKDMGSLGEVTYQL-----IDPTVSAGETSGYDRFRV--DDSGM 951
Query: 1001 VIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+ L + ++L A DGG+ L + V + V +D F + Y+ ++ E
Sbjct: 952 IESTNILTANTLYKLQAKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENS 1011
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ + AT + G ++ + Y + Q + + F I VL + +LDRE
Sbjct: 1012 PLNTEVFRATATKS--GSSSGIAYSLVGGQIENGNTMFSIDSSGRVLLLR-QLDRERTKS 1068
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD----ELLEWKHPEADEL--- 1168
Y L V G DVNDN+P F FD + + + A+ +
Sbjct: 1069 YKLYVRGTYTGGSLTLATDVECLVTVTDVNDNTPLF-TFDRVNKQFVVDNYAPANTIIAT 1127
Query: 1169 ----SNHNFESVMMIPVYKATIEENAPIG-TTVAKVFANDTDFIGNGNGLILYSLPQRKN 1223
+ + + + T+ NAP T + V T + +I Y + R
Sbjct: 1128 LRAVDSDEGANAQVTMSIQGTVPSNAPFTIDTPSNVLKTTTKL----STVIDYQITVRAT 1183
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ G P S ++V V ++ PVF Y ++++EN +++S+ T
Sbjct: 1184 DK--GSPPQYSETTVIVKVLNI------QTPPVFGQAKYTVDVQENTKVGQQVISVKATY 1235
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
N ++Y ++ N D F ID +G + + + DREV +Y + VR
Sbjct: 1236 GDSNALLQYSFVSGNLGD---AFCID-SSGQITVAQPLDREVLPSYTLRVR--------- 1282
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
V G + +VVV + D+ND+SP FT
Sbjct: 1283 -----------VALGNNEDFTEVVVSLTDINDDSPTFT 1309
Score = 66.5 bits (155), Expect = 5e-09
Identities = 41/136 (30%), Positives = 74/136 (54%), Gaps = 6/136 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+D G + Y L +G+D F++D +G+L +K D + Q+ V+ +
Sbjct: 1844 IKATDRDTGDAGVVTYFLKAGSDEH-FAIDVNSGTLTTKKSFDREG----QSLFSVIVIA 1898
Query: 278 ASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ NNP + + V++ ++D ND+ P+F+ + S+ E+ G S+L+V+ATD+D G
Sbjct: 1899 RDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIG 1958
Query: 337 ENGEFTYQLDDPKGAF 352
+N + Y + G F
Sbjct: 1959 DNAKLEYFISGGDGRF 1974
Score = 64.1 bits (149), Expect = 3e-08
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 10/177 (5%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDS--VNGSLFLE-KELDLDAEHNLQANTF 272
E HA D+D RYE++SGN+R F ++ V FL K + + +
Sbjct: 155 EKCHAEDKDRS--GIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 212
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L V+A+ T R++I++ D N+N P FE Y +++ E+ P S+L+V A D
Sbjct: 213 TLTVRANDGGGLHGTT--RIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARD 270
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D G NG Y L + + F+ID +G +R +LD ++ ++V A++ S
Sbjct: 271 ADIGRNGGIYYYLRNTQD-FTIDAITG--VIRPIRMLDFQSGQQRTLEVTARDRGSS 324
Score = 64.1 bits (149), Expect = 3e-08
Identities = 45/164 (27%), Positives = 84/164 (51%), Gaps = 14/164 (8%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A L+Y +SGN F +DS +G + + + LD + ++ L+V+ + NN T
Sbjct: 1240 ALLQYSFVSGNLGDAFCIDS-SGQITVAQPLDREV-----LPSYTLRVRVALGNNEDFT- 1292
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--- 345
V + L D+ND+ P F Y E++ +G S+ +V ATD+D G +G+ +Y+
Sbjct: 1293 --EVVVSLTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYA 1350
Query: 346 DDPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
D + F +D +G +++ + LD E + +++Y ++ N
Sbjct: 1351 SDIQSMDKFDLDQTTGIISLASGKSLDYEDITIAEVRIYLRDIN 1394
Score = 64.1 bits (149), Expect = 3e-08
Identities = 61/226 (26%), Positives = 97/226 (42%), Gaps = 18/226 (7%)
Query: 939 LIPENIPIGTTIIK----LNALDLDSG-LNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
++PE T I + L +L ++S L + + P K +AD E ++ V
Sbjct: 1708 IVPETTRAXTVITRVPRILESLSVNSDVLKVSAQAPGGKSIVYSPVKANADIDE--KFSV 1765
Query: 994 INERHGHVIVARSL------PPESEFRLNISALDGG-NLNDNISVRVFVKDVNDHFPVFK 1046
E +G + A L P + F+L + A + NL SV + ++DVND P F
Sbjct: 1766 --ETNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYSTCSVAITLEDVNDDKPTFD 1823
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
Y+ V E + + ATD D G +TYF++ + +D F I +G L+
Sbjct: 1824 LGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLK-AGSDEHFAIDVNSGTLTTKK 1882
Query: 1107 ELDRETEDKYILTVVARDNGXX-XXXXXXXXXXXXXXDVNDNSPKF 1151
DRE + + + V+ARD G D ND+ P+F
Sbjct: 1883 SFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQF 1928
Score = 64.1 bits (149), Expect = 3e-08
Identities = 75/291 (25%), Positives = 119/291 (40%), Gaps = 29/291 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE--KAFIFLIAPIGPSLTI 130
G N++S T+Y+ D ND+ P+F + TV E G + GP+ +
Sbjct: 2232 GANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAEL 2291
Query: 131 PLTVPRGLTIFKDIRAF--DRDKPNTPNSDV-------HYSIVSGNDDGHFALESSHKPV 181
V G + AF D K S + Y++ D + S + P
Sbjct: 2292 EFVVTHG----NEPAAFYVDPSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSDNSPA 2347
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISG 238
+L + D A D + K + +++ P+ A+D D G A +++ G
Sbjct: 2348 YVLITITD--ANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGG 2405
Query: 239 NDRKLFSL--DSVNGSL-FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
N LF + + N SL + L LD E T + ++ + + T +A V +
Sbjct: 2406 NPDDLFEVVPNPDNSSLGIVRTRLPLDRE-----TTPIHHLEITAKDTGGLTGKAHVWLT 2460
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQL 345
LLD+NDN P F+ F+ I EN+ V +V A D D NG FTY +
Sbjct: 2461 LLDVNDNGPWFQPPFFVGKIKENVNVKQFVTKVSANDPDTKNNGAPFTYAI 2511
Score = 60.5 bits (140), Expect = 3e-07
Identities = 59/221 (26%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E++ +G+ ++ + A+D DSG N + ++ P D EV V N +
Sbjct: 2372 VAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGG---NPD----DLFEV----VPNPDNS 2420
Query: 1000 HVIVARS-LPPESE----FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + R+ LP + E L I+A D G L V + + DVND+ P F+ ++ +
Sbjct: 2421 SLGIVRTRLPLDRETTPIHHLEITAKDTGGLTGKAHVWLTLLDVNDNGPWFQPPFFVGKI 2480
Query: 1055 EEAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDT--DLPFEISPLTGV---LSVNGEL 1108
+E ++ + KV A D D N A TY I + F+I+ +T V +S +G
Sbjct: 2481 KENVNVKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTTDMSSSGTF 2540
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
DRET + + + D+G D NDN P
Sbjct: 2541 DRETMTTWTIGIAGTDSGRPAKSNFTYVYVDVQDD-NDNEP 2580
Score = 60.1 bits (139), Expect = 5e-07
Identities = 52/175 (29%), Positives = 85/175 (48%), Gaps = 14/175 (8%)
Query: 218 IHAIDQDLG-VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G LRY L SGN+ F++DS +G + L+ +L+ N + L V
Sbjct: 384 VKANDPDAGSTNGQLRYSL-SGNNN--FAIDSTSGVVTLQTQLEYKG--NPAQDVIDLVV 438
Query: 277 QASQLNNP--LKTAQARVEIELLDLNDN--LPEFEVDFYNISIVENLPNGFSVLQVMATD 332
A+ N +A ++IE+LD++DN P F +++ E+ G ++ +V ATD
Sbjct: 439 TATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATD 498
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G +G+ Y + G F + +G L V LDRE S + + A++
Sbjct: 499 SDDGSDGQVVYSIIQGSGLGVFQVQATTGDLIV--AAPLDREKMSFYDLVIKAED 551
Score = 60.1 bits (139), Expect = 5e-07
Identities = 68/229 (29%), Positives = 101/229 (44%), Gaps = 33/229 (14%)
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLG--PLF-------LIPENIPIGTTIIKLNALDL 958
T NG +G V K + LDVD P+F + E+ +G TI +++A D
Sbjct: 441 TDRNGQSGALSASVNLKIE-VLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDS 499
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLN 1016
D G +GQ+ Y S + L V F + G +IVA L E S + L
Sbjct: 500 DDGSDGQVVY----------SIIQGSGLGV---FQVQATTGDLIVAAPLDREKMSFYDLV 546
Query: 1017 ISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
I A D + N+ V V ++DV+DHFP F + Y E + V D D
Sbjct: 547 IKAEDKATFPKSSNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDL 606
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE-DKYILTVVA 1122
G+ +++Y I + + F+I P +G++ G +D TE Y L V A
Sbjct: 607 GE--SVSYSITGASS---FKIVPTSGLILTTGPIDLTTEPSTYELVVTA 650
Score = 59.3 bits (137), Expect = 8e-07
Identities = 92/387 (23%), Positives = 162/387 (41%), Gaps = 43/387 (11%)
Query: 755 TVIAEFNKGVISGAGIY-QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
T+IA + V S G QVT+ I+ + F T + +K+ T I ++
Sbjct: 1123 TIIATL-RAVDSDEGANAQVTMSIQGTVPSNAPFTIDTPSNVLKTTTKLSTVIDYQITVR 1181
Query: 814 ATDA------DEGT---NALFMYT--LFGEGKEMFDVDENTGVVKFIGD--SLDREKKIM 860
ATD E T L + T +FG+ K DV ENT V + + + + +
Sbjct: 1182 ATDKGSPPQYSETTVIVKVLNIQTPPVFGQAKYTVDVQENTKVGQQVISVKATYGDSNAL 1241
Query: 861 YKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIE 920
+ S V+ + G +A I G +P ++ + +R+ N ++
Sbjct: 1242 LQYSFVSGNLG----DAFCIDSSGQITVAQPLDREVLPSYTLRVRVALGNNEDFTEVVVS 1297
Query: 921 VKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
+ N + + F E+I GT+I K+ A D DSG +GQI Y F
Sbjct: 1298 LTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRF---------- 1347
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVND 1040
L A ++ F +++ G + +A + E +I+ + VR++++D+ND
Sbjct: 1348 LYASDIQSMDKFDLDQTTGIISLASGKSLDYE---DITIAE---------VRIYLRDIND 1395
Query: 1041 HFPVFKKTWYNFNVE-EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT 1099
+ P F Y+ + +A V+ +V ATD D N + Y I + + F++
Sbjct: 1396 NDPKFSAASYHAKLSLDAPVLEHVV-QVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDN 1454
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNG 1126
G++ V L ++LT+ A D+G
Sbjct: 1455 GLIRVAKSLTTVAASSFLLTLEAADSG 1481
Score = 56.8 bits (131), Expect = 4e-06
Identities = 53/173 (30%), Positives = 79/173 (45%), Gaps = 11/173 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS-Q 280
D LG A +RY L K F +D+ N +L +E+ LD E + N+F + V A+ Q
Sbjct: 2177 DPYLGGNAEIRYTLTDNAGGK-FKIDA-NTALVTTEEI-LDRETS--PNSFTITVLATDQ 2231
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG- 339
N L T + I + D ND+ P F + ++ E++ G+ V V ATD D G N
Sbjct: 2232 GANKLSTTKVAT-IYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAE 2290
Query: 340 -EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
EF + AF +DP G TV +L+ S + V + V+
Sbjct: 2291 LEFVVTHGNEPAAFYVDPSKG--TVHVSGILNYTLRKSYNLTVTVSDRGMPVL 2341
Score = 55.6 bits (128), Expect = 1e-05
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GENGEFTY 343
T A +EI + D+NDN P F Y + EN G SV+ V A D D G N E Y
Sbjct: 2129 TGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRY 2188
Query: 344 QL-DDPKGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKETNPSVVGT 393
L D+ G F ID + +T + +LDRE + +S + V A + + + T
Sbjct: 2189 TLTDNAGGKFKIDANTALVT--TEEILDRETSPNSFTITVLATDQGANKLST 2238
Score = 55.2 bits (127), Expect = 1e-05
Identities = 85/333 (25%), Positives = 136/333 (40%), Gaps = 43/333 (12%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTP--------------TGEKAFIFLIAPIGPS 127
SV + +EDVND+ P F Y V E P TG+ + G
Sbjct: 1807 SVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSD 1866
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
+ V G K ++FDR+ + S + + GN+ G + E + K +++
Sbjct: 1867 EHFAIDVNSGTLTTK--KSFDREGQSL-FSVIVIARDKGNNPGALSEEVAVKVLVVDEND 1923
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
EFQ + S I IL + A DQD+G A L Y + G+ R F++
Sbjct: 1924 SPPQFDQAEFQTSVSESAT-IGTSIL---EVVATDQDIGDNAKLEYFISGGDGRFWFAVQ 1979
Query: 248 SVNGSLFLEKELDLDAEHNLQA-NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+++ S E+ +DA + + +++ + V A+ + +A RV I + D ND +P F
Sbjct: 1980 TISKSGRTYGEVQVDARLDFETKSSYTIDVTAT---DGRFSATTRVLITITDANDIVPMF 2036
Query: 307 EV--------DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
Y + E +G VL+V A D D + Y L+ F+I R
Sbjct: 2037 MTLTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD---SPNIQYTLEGSSSYFTIAARQ 2093
Query: 359 ------GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G ++ +Q LDREA V AK+
Sbjct: 2094 EGGKFVGIISTGSQP-LDREATPIFSFNVLAKD 2125
Score = 54.4 bits (125), Expect = 2e-05
Identities = 81/345 (23%), Positives = 145/345 (42%), Gaps = 36/345 (10%)
Query: 580 FWVGS--NVGIGTSVGQIRV--NDAFEQNDVSYDLLH-----GYEEGVP-FAVEERSGVI 629
FW + TSV Q+ + D +V+Y L+ G G F V++ SG+I
Sbjct: 894 FWASKPDTLPTDTSVMQLPIIDKDMGSLGEVTYQLIDPTVSAGETSGYDRFRVDD-SGMI 952
Query: 630 TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGAHSPIIFHV 688
+ L+ +Y +A A S ATV V + V ++ + +P +
Sbjct: 953 ESTNILTA--NTLYKLQAKAKDGG---SPALEATVDVFISVYPSSDTPVRFSQNPYSASI 1007
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIAEDGTIFTQKPLDRE 747
ENS ++F + G+ +G L+ Q ++ +I G + + LDRE
Sbjct: 1008 AENSPLNT--EVFRATATKS-GSSSGIAYSLVGGQIENGNTMFSIDSSGRVLLLRQLDRE 1064
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE-HATYEGFIMENSKIGTEI 806
+ Y++ V + G ++ A + + + D NDN P+F + F+++N I
Sbjct: 1065 RTKSYKLYVRGTYTGGSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTI 1124
Query: 807 KMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLS 864
++A D+DEG NA ++ G F +D + V+K + I Y+++
Sbjct: 1125 IA--TLRAVDSDEGANAQVTMSIQGTVPSNAPFTIDTPSNVLK---TTTKLSTVIDYQIT 1179
Query: 865 LVARDTGGLSSEAELIIMIGDEN-DNKPEFNQ------IEENSKV 902
+ A D G +E +++ N P F Q ++EN+KV
Sbjct: 1180 VRATDKGSPPQYSETTVIVKVLNIQTPPVFGQAKYTVDVQENTKV 1224
Score = 53.2 bits (122), Expect = 5e-05
Identities = 29/80 (36%), Positives = 40/80 (50%)
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
A+ F ++ + N P A +VE+ + D N P F + S + LP SV+Q+
Sbjct: 852 ASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLPTDTSVMQL 911
Query: 329 MATDKDQGENGEFTYQLDDP 348
DKD G GE TYQL DP
Sbjct: 912 PIIDKDMGSLGEVTYQLIDP 931
Score = 53.2 bits (122), Expect = 5e-05
Identities = 67/321 (20%), Positives = 131/321 (40%), Gaps = 24/321 (7%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
VR+ G N+ + V V + D+ND+ P F + Y +E +G I +A
Sbjct: 1281 VRVALGNNE--DFTEVVVSLTDINDDSPTFTKSVYEFFANEDISSGTS--IGKVAATDRD 1336
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
+ DI++ D+ + + S+ SG + + + + L
Sbjct: 1337 SGSHGQISYRFLYASDIQSMDKFDLDQTTGII--SLASGKSLDYEDITIAEVRIYLR--- 1391
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEIL-FPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
D + D +F + + +L + A D D +RY +++GN F +
Sbjct: 1392 -DINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQV 1450
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+ NG + + K L + A++F+L ++A+ +P + V++ + L D P+F
Sbjct: 1451 LTDNGLIRVAKSLT-----TVAASSFLLTLEAADSGDPERKGSVNVQVNVF-LPDGPPKF 1504
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDK-DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
+D ++ N G + Q +A K E ++ + F+I+P SG +
Sbjct: 1505 VLD----PVIVNATEGIAANQRVAVAKAATSEALKYEILSGNTNDMFAINPSSGVILTTR 1560
Query: 366 QTVLDREAHSSLRMKVYAKET 386
+ LD E + M + A++T
Sbjct: 1561 E--LDYEEATGYIMNIIARDT 1579
Score = 53.2 bits (122), Expect = 5e-05
Identities = 59/213 (27%), Positives = 88/213 (41%), Gaps = 30/213 (14%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
P+ ++++ A DLD+ NG+IRY S A + F + +G + VA
Sbjct: 1414 PVLEHVVQVTATDLDTANNGRIRY-------------SIVAGNQEGAFQVLTDNGLIRVA 1460
Query: 1005 RSLPP--ESEFRLNISALDGGNLND----NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+SL S F L + A D G+ N+ V VF+ D F V N A
Sbjct: 1461 KSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVFLPDGPPKF-VLDPVIVNATEGIAA 1519
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
R + K ++A L Y I +T+ F I+P +GV+ ELD E YI+
Sbjct: 1520 NQRVAVAKAATSEA-------LKYEILSGNTNDMFAINPSSGVILTTRELDYEEATGYIM 1572
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ARD ++NDN P F
Sbjct: 1573 NIIARD---TRDRSASVQVIINVVNINDNEPMF 1602
Score = 52.8 bits (121), Expect = 7e-05
Identities = 48/177 (27%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 732 IAEDGTIFTQKPL---DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I+EDG + T+ PL D E+ ++Y +TV+ +G+ G + + I + D N+ P F
Sbjct: 76 ISEDGVVVTKNPLVYTDGEE-NLYVLTVLRR-QRGMTEGGIAWTLRITVTDTNNFQPTFG 133
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN--TGVV 846
Y G+I E + GT + + K D+ + + Y + + + V E G
Sbjct: 134 ADFYLGYIAEEAAQGTTV--GGLEKCHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQ 191
Query: 847 KFI-----GDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
KF+ + R+ + L++ A D GGL + I I D N+N P F + E
Sbjct: 192 KFLVLKATNTRIVRDPARPSITLTVRANDGGGLHGTTRIQIDIQDTNNNPPVFEKSE 248
Score = 52.0 bits (119), Expect = 1e-04
Identities = 59/239 (24%), Positives = 105/239 (43%), Gaps = 21/239 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + ++ V + L D NDN+P F ++ Y + +A V + +V A D D NG +
Sbjct: 1377 DYEDITIAEVRIYLRDINDNDPKFSAAS-YHAKLSLDAPVLEHVVQVTATDLDTANNGRI 1435
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLA 553
Y + + F++ + G + VA+S + L +EA+D + ER+ S+
Sbjct: 1436 RYSIVAGNQ---EGAFQVLTDNGLIRVAKSLTTVAASSFLLTLEAAD--SGDPERKGSVN 1490
Query: 554 V-VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V V + + G P F+ P V + GI + ++ V A + Y++L
Sbjct: 1491 VQVNVFLPDGP-------PKFVLDP--VIVNATEGIAAN-QRVAVAKAATSEALKYEILS 1540
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G + FA+ SGVI +L Y +A ++ + S ++VV++ND
Sbjct: 1541 GNTNDM-FAINPSSGVILTTRELDYEEATGYIMNIIA-RDTRDRSASVQVIINVVNIND 1597
Score = 50.8 bits (116), Expect = 3e-04
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y +I G+ +F + + G L + LD + + + + L ++
Sbjct: 494 VSATDSDDGSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLDRE-----KMSFYDLVIK 548
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A K++ V +++ D++D+ P+F Y E P V V D D GE
Sbjct: 549 AEDKATFPKSSNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGE 608
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
+ +Y + +F I P SG + L E S+ + V A TN
Sbjct: 609 S--VSYSITG-ASSFKIVPTSGLILTTGPIDLTTEP-STYELVVTATSTN 654
Score = 50.0 bits (114), Expect = 5e-04
Identities = 50/221 (22%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 156 NSDVHYSIVSGNDDGHFALESSHKPVL---LLRKVL-DYD-------AGDKEFQLVIMAS 204
N+ + YS VSGN F ++SS + + L R+VL Y +++F V+++
Sbjct: 1239 NALLQYSFVSGNLGDAFCIDSSGQITVAQPLDREVLPSYTLRVRVALGNNEDFTEVVVSL 1298
Query: 205 GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAE 264
F + ++ + + + ++ DR S ++ ++ +
Sbjct: 1299 TDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSMDK 1358
Query: 265 HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS 324
+L T ++ + + + + A V I L D+NDN P+F Y+ + + P
Sbjct: 1359 FDLDQTTGIISLASGKSLDYEDITIAEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEH 1418
Query: 325 VLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTV 363
V+QV ATD D NG Y + + +GAF + +G + V
Sbjct: 1419 VVQVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRV 1459
Score = 49.6 bits (113), Expect = 6e-04
Identities = 74/339 (21%), Positives = 139/339 (41%), Gaps = 69/339 (20%)
Query: 60 DFDEGDDLVRIGAGLN---QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA 116
D D+ ++ + +G + + V +Y+ D+NDN P F YH A
Sbjct: 1360 DLDQTTGIISLASGKSLDYEDITIAEVRIYLRDINDNDPKFSAASYH------------A 1407
Query: 117 FIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
+ L AP+ L + A D D N N + YSIV+GN +G F + +
Sbjct: 1408 KLSLDAPV-------------LEHVVQVTATDLDTAN--NGRIRYSIVAGNQEGAFQVLT 1452
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGK-------RIHKEILFPE--PIHAIDQDL-- 225
+ + + + + A L SG + + P+ P +D +
Sbjct: 1453 DNGLIRVAKSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVFLPDGPPKFVLDPVIVN 1512
Query: 226 ---GVGAT-------------LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA 269
G+ A L+YE++SGN +F+++ +G + +ELD + +A
Sbjct: 1513 ATEGIAANQRVAVAKAATSEALKYEILSGNTNDMFAINPSSGVILTTRELDYE-----EA 1567
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF---YNISIVENLPNGFSVL 326
+++ + A + ++A +V I ++++NDN P F + + + G
Sbjct: 1568 TGYIMNIIARDTRD--RSASVQVIINVVNINDNEPMFPGETNGQIDRKVAGPFAPGVIAT 1625
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
++ A DKD G+ + + + + F+ID R G L +N
Sbjct: 1626 RLTAVDKDIGDRVYYKISI-EAENYFTIDER-GQLICKN 1662
Score = 49.2 bits (112), Expect = 9e-04
Identities = 59/222 (26%), Positives = 85/222 (38%), Gaps = 22/222 (9%)
Query: 932 DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY 991
D++ F++ P T I L A+D D G N Q+ V PS
Sbjct: 1107 DRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTV---PSNAP--------- 1154
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHF-PVFKKTWY 1050
F I+ + L ++++ + A D G+ V VK +N PVF + Y
Sbjct: 1155 FTIDTPSNVLKTTTKLSTVIDYQITVRATDKGSPPQYSETTVIVKVLNIQTPPVFGQAKY 1214
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+V+E + + V AT D NA L Y + F I +G ++V LDR
Sbjct: 1215 TVDVQENTKVGQQVISVKATYGD--SNALLQYSFVSGNLGDAFCIDS-SGQITVAQPLDR 1271
Query: 1111 ETEDKYILTV-VARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E Y L V VA N D+ND+SP F
Sbjct: 1272 EVLPSYTLRVRVALGNN-----EDFTEVVVSLTDINDDSPTF 1308
Score = 48.8 bits (111), Expect = 0.001
Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 17/156 (10%)
Query: 226 GVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
G + + Y L+ G N +FS+DS +G + L ++LD + + ++ L V+ +
Sbjct: 1026 GSSSGIAYSLVGGQIENGNTMFSIDS-SGRVLLLRQLDRE-----RTKSYKLYVRGTYTG 1079
Query: 283 NPLKTA-QARVEIELLDLNDNLPEFEVDFYNIS-IVEN-LPNGFSVLQVMATDKDQGENG 339
L A + + D+NDN P F D N +V+N P + + A D D+G N
Sbjct: 1080 GSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANA 1139
Query: 340 EFTYQLDD--PKGA-FSIDPRSGWL--TVRNQTVLD 370
+ T + P A F+ID S L T + TV+D
Sbjct: 1140 QVTMSIQGTVPSNAPFTIDTPSNVLKTTTKLSTVID 1175
Score = 48.0 bits (109), Expect = 0.002
Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 32/234 (13%)
Query: 1174 ESVMMIPVY-KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
+S++ PV A I+E + T A+ D+ G + L R ++N L S
Sbjct: 1746 KSIVYSPVKANADIDEKFSVETNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYST 1805
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK--M 1290
S AI T+ DV D DKP F Y+ + EN ++++ T+ +
Sbjct: 1806 CSVAI---TLEDVND-----DKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVV 1857
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y++ +D F ID +GTL +S DRE + + VIV A R K +
Sbjct: 1858 TYFLKAGSDEH----FAIDVNSGTLTTKKSFDREGQSLFSVIVIA-RDKGNN-------- 1904
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
G +V V V + D ND+ P+F T++ +A G ++++
Sbjct: 1905 ------PGALSEEVAVKVLVVDENDSPPQFDQAE--FQTSVSESATIGTSILEV 1950
Score = 41.1 bits (92), Expect = 0.23
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
+V +TLLD NDN P F P + +K N V + KV A DPD NG
Sbjct: 2456 HVWLTLLDVNDNGPWFQPP-FFVGKIKENVNVKQFVTKVSANDPDTKNNG 2504
Score = 36.3 bits (80), Expect = 6.5
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAP-RFAIDPVSGTVRVVAAL 1479
+TS ATD+D G NA++ + + + P F +DP GTV V L
Sbjct: 2275 VTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGIL 2319
>UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
SCAF14485, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 3280
Score = 129 bits (311), Expect = 7e-28
Identities = 151/530 (28%), Positives = 228/530 (43%), Gaps = 60/530 (11%)
Query: 408 LETNAPLEK-TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYE 466
L APL++ TT F V T T+ +E+ + V +V LLD NDN PVF+ +
Sbjct: 1477 LTVTAPLDRETTSSFAFTV-TATDQARRKEERKQATVAAQVFLLDVNDNRPVFI--SAVS 1533
Query: 467 FSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL---QRTSNLTITSP------FKINP-- 515
+ +A+VG+++ + A D D G+NG+V Y + + T+ F ++P
Sbjct: 1534 VQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKGMFTLEGNTGKMPLFCLHPLC 1593
Query: 516 -----------NTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ G + +A + E + H L VEA D PS S T+EV
Sbjct: 1594 FSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVEAVDH-GLPS--LSSTQTFTVEV--A 1648
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVS-YDLL--HGYEEGV 618
++P P F + Y V N G V ++ D E+N V Y LL GYE
Sbjct: 1649 DVNDQP--PVFSQSVYNASVAENKDPGEPVARVSATDGDSEENAVVWYSLLPGPGYE--- 1703
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLL 677
F++ +G+IT L R + + A LS V+D ND +
Sbjct: 1704 LFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATVLCSVLDDNDNPPAFM 1763
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDG 736
+ S + EN AI HT +S G G + + I + + G
Sbjct: 1764 Q---SSFRISLPENLPPGAI----HTAQASDPDLGENGTILYSIVGEDCAGCFTVNSRSG 1816
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ T K LDRE++ Y +T+ A + G + Q+ + + D NDN P F +Y+ +
Sbjct: 1817 VVSTTKVLDREEKQNYTLTIQAR-DYGPTPLSSSTQLQLVLLDRNDNAPSFSRKSYQASV 1875
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDR 855
E G E+ + A D DEG N Y+L + + F VD TGV++ G LDR
Sbjct: 1876 SEGLPPGAEVLR---VSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLTGVIRTTG-PLDR 1931
Query: 856 EKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
E + Y L VA D G L+S A + + + D NDN P +Q N+ V
Sbjct: 1932 ESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQNPVNAWV 1981
Score = 125 bits (302), Expect = 8e-27
Identities = 127/479 (26%), Positives = 218/479 (45%), Gaps = 33/479 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + + +LD NDN PVF + Y S+ +A + + + +V A D DLG NG + Y++ R
Sbjct: 215 LQLRIHVLDENDNPPVFNQTE-YHASVPEDAPLMSPVCQVHATDLDLGDNGRITYEINRR 273
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F IN +G V V + E + H L V A+D A P + V + +
Sbjct: 274 QS-DPDRVFSINRTSGVVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVGVRVLNIN 332
Query: 561 RGTKGNKPDIPD-FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
+ P I F+ + V G+G V +I V+D Q + L G ++G
Sbjct: 333 ----DHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQEERVAVTLEG-DDG-K 386
Query: 620 FAVEERSG---VITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGV 675
F +++ + + V DL R + +Y+ + A + LS + V D ND
Sbjct: 387 FTLKQTADFLYALYVSADLDREEKDLYELKVRASDLGSPPLSSEVVFLLRVTDANDCHPQ 446
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAIAE 734
K A++ + ++ G+++ Q+ + G VR+ ++ + QD I E
Sbjct: 447 FEKDAYTVSV--PEDVPQGSSLIQLQARDADE---GPNGAVRYSILRSNQDRLVSIE-PE 500
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G + T PLDRE + V+A + G S + VT+ + D NDN PVF+ Y
Sbjct: 501 SGLVATAAPLDRESLEQLWFLVVAA-DGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGA 559
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKE---MFDVDENTGVVKFI 849
+ E+S +G+ + ATDAD +Y+L +G++ +F V +G + +
Sbjct: 560 SVPEHSAVGSCFLQ---VVATDADSPAFGTLLYSLSDGFDGQDQHPLFHVHPQSGEL-CV 615
Query: 850 GDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+DR+ + ++ L + A D GGLS++ + + + D NDN P FN E + H +
Sbjct: 616 SQDIDRDSGQTVHDLLIRAEDPGGLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISGHAQ 674
Score = 125 bits (301), Expect = 1e-26
Identities = 184/736 (25%), Positives = 291/736 (39%), Gaps = 70/736 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFV---PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+L + V + + D NDN P F+ S + + G+++ + A D D G+NG
Sbjct: 1179 RLNATATVHILVTDTNDNTPQFMHLPASKEVNVQIWAEIPAGSLVANMFAKDLDAGENGT 1238
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSL 552
V + L + + F+I+ TG + E R + L V ASD A P E +
Sbjct: 1239 VTFSLA-SEDEGEPPHFEIDGETGNIRTTEHFTRNTRPFYTLTVCASDGGAPPLEH---V 1294
Query: 553 AVVTIEVTRGTKG--NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
AVV ++V G++ + + P F V + + T +G RV D + Y +
Sbjct: 1295 AVVHVQV-HGSEAVDGRAEHP----LVRRFTVREDAELATVIGSARVPD---EGRFRYSI 1346
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDV 669
G + V F ++ SG I V L Y V E A L+ NA+V V V V
Sbjct: 1347 SEG-DGSVQFGIDASSGDIYVNQPLDYEAAAQYVL--VVRAEGAGLAPGANASVLVSVMV 1403
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIANQQDVTD 728
D ++ + E++ ++ F + + N VR+ + VTD
Sbjct: 1404 EDANDHTPWFPDKMVLLGLSEDATVGSLAFAFQARDADGTFPNSA--VRYGLTYDPKVTD 1461
Query: 729 DIAIAE------DGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDE 780
G++ PLDRE + TV A + + +++ D
Sbjct: 1462 SSTRFPFQMNPYTGSLTVTAPLDRETTSSFAFTVTATDQARRKEERKQATVAAQVFLLDV 1521
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV 839
NDN PVF A +ME++++G+ + A D DEG N L YT+ G K MF +
Sbjct: 1522 NDNRPVFISAVSVQ-VMEDAEVGSLLHR---FVAKDGDEGENGLVSYTILTGNKKGMFTL 1577
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ NTG + ++ L + L L+ + + +++
Sbjct: 1578 EGNTGKMPLF---------CLHPLCFSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVE 1628
Query: 900 SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD 959
+ H L+ T FT+ EV N Q + EN G + +++A D D
Sbjct: 1629 AVD--HGLPSLSSTQTFTV-EVADVNDQPPVFSQSVYNASVAENKDPGEPVARVSATDGD 1685
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNI 1017
S N + Y S L E+ F IN G + A L E + F L +
Sbjct: 1686 SEENAVVWY----------SLLPGPGYEL---FSINPDTGLITTASYLDREQQHGFTLRV 1732
Query: 1018 SALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG 1075
A D G L+ +V V D ND+ P F ++ + ++ E + A+D D G
Sbjct: 1733 QARDSGPRPLSATATVLCSVLDDNDNPPAFMQSSFRISLPE-NLPPGAIHTAQASDPDLG 1791
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
+N + Y I D F ++ +GV+S LDRE + Y LT+ ARD G
Sbjct: 1792 ENGTILYSIVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYG-PTPLSSST 1850
Query: 1136 XXXXXXXDVNDNSPKF 1151
D NDN+P F
Sbjct: 1851 QLQLVLLDRNDNAPSF 1866
Score = 107 bits (258), Expect = 2e-21
Identities = 128/515 (24%), Positives = 221/515 (42%), Gaps = 52/515 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V ++LD NDN P F+ S+ + S+ N G I +A DPDLG+NG +LY
Sbjct: 1742 LSATATVLCSVLDDNDNPPAFMQSS-FRISLPENLPPGA-IHTAQASDPDLGENGTILYS 1799
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVT 556
+ F +N +G VS + E + + L ++A D P L +V
Sbjct: 1800 IVGED---CAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVL 1856
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
++ + P F Y+ V + G V ++ D E V+Y L
Sbjct: 1857 LD-------RNDNAPSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDS 1909
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ--ENANLSIVTNATVHVVDVNDE 672
+G F+V+ +GVI L R +R Y AVA L+ V + TV V DVND
Sbjct: 1910 SQGA-FSVDSLTGVIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDN 1968
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIA 731
+ +P+ V SA QI T + G G ++F +++++++ D
Sbjct: 1969 VPIC---DQNPVNAWV---SARTLPNQIVATVTAEDSDQGENGTIQFALSDEENLFD--I 2020
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
E G I ++ + ++++ + V++ + V I+++ EN+ F +
Sbjct: 2021 NRETGEISVRRRVRAGFSGRKLEVMVSDRGRPVLTSTCL--VFIHLKGENEGLQ-FTNKV 2077
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIG 850
Y I ENS G + ++A+ + G+ +YT+F G +F ++ +TG ++
Sbjct: 2078 YNATIKENSGAGILVTK---VEAS-GEAGSRQSVVYTIFSGNENSLFSINHHTGEIRVQK 2133
Query: 851 D-SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV---RIHR 906
D +LD E L ++A D G ++ + I + D NDN P F + + V + H
Sbjct: 2134 DYALDFELSPHIHLVVLA-DNGLQTTHCRVSIHLLDVNDNAPRFERSSYRTAVWEGQAHN 2192
Query: 907 -----------ETKLNGTAGFTIIEVKPKNKFALD 930
++ +NG ++I+ P F LD
Sbjct: 2193 TYVMQMFASDADSGINGQIEYSIVSGDPNEAFILD 2227
Score = 104 bits (250), Expect = 2e-20
Identities = 93/323 (28%), Positives = 142/323 (43%), Gaps = 20/323 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
GL +S+ + TV + DVND P+F + Y+ +V E GE + ++
Sbjct: 1633 GLPSLSSTQTFTVEVADVNDQPPVFSQSVYNASVAENKDPGEP--VARVSATDGDSEENA 1690
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF----ALESSHKPVLLLRKVL 188
V L F + P+T + G A +S +P+ VL
Sbjct: 1691 VVWYSLLPGPGYELFSIN-PDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATVL 1749
Query: 189 DYDAGDKEFQLVIMASGKRIH-KEILFPEPIH---AIDQDLGVGATLRYELISGNDRKLF 244
D + M S RI E L P IH A D DLG T+ Y ++ + F
Sbjct: 1750 CSVLDDNDNPPAFMQSSFRISLPENLPPGAIHTAQASDPDLGENGTILYSIVGEDCAGCF 1809
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+++S +G + K LD + + N + L +QA ++ ++++ LLD NDN P
Sbjct: 1810 TVNSRSGVVSTTKVLDREEKQN-----YTLTIQARDYGPTPLSSSTQLQLVLLDRNDNAP 1864
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
F Y S+ E LP G VL+V A D D+G NG TY L D +GAFS+D +G
Sbjct: 1865 SFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLTG--V 1922
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
+R LDRE+ + ++ A +
Sbjct: 1923 IRTTGPLDRESRAQYTLRAVATD 1945
Score = 97.1 bits (231), Expect = 3e-18
Identities = 122/501 (24%), Positives = 200/501 (39%), Gaps = 41/501 (8%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
E +++ L S V + D ND PVF S +Y S+ N G + +V A D D
Sbjct: 1628 EAVDHGLPSLSSTQTFTVEVADVNDQPPVFSQS-VYNASVAENKDPGEPVARVSATDGDS 1686
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR 549
+N +V Y L + F INP+TG ++ A E +H + + + P R
Sbjct: 1687 EENAVVWYSLLPGPGYEL---FSINPDTGLITTASYLDREQQHGFTLRVQARDSGP---R 1740
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGT-SVGQIRVNDAFEQNDVSY 608
A T+ + + P P FM + + + N+ G Q D E + Y
Sbjct: 1741 PLSATATVLCSVLDDNDNP--PAFMQSSFRISLPENLPPGAIHTAQASDPDLGENGTILY 1798
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVV 667
++ G + F V RSGV++ L R + Y A LS T + ++
Sbjct: 1799 SIV-GEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLL 1857
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
D ND + ++ V E A ++ + G V + +
Sbjct: 1858 DRNDNAPSFSRKSYQA---SVSEGLPPGA--EVLRVSAFDPDEGPNGRVTYSLTEDSSQG 1912
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG--AGIYQVTIYIEDENDNPP 785
+ G I T PLDRE R Y + +A G G + VT+ +ED NDN P
Sbjct: 1913 AFSVDSLTGVIRTTGPLDRESRAQYTLRAVA--TDGCTQGPLTSVASVTVQVEDVNDNVP 1970
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
+ + ++ + + +I + A D+D+G N + L E + +FD++ TG
Sbjct: 1971 ICDQNPVNAWVSART-LPNQIVA--TVTAEDSDQGENGTIQFALSDE-ENLFDINRETGE 2026
Query: 846 VKFIGDSLDREKKIMY---KLSLVARDTGG--LSSEAELIIMIGDEND-----NKPEFNQ 895
+ S+ R + + KL ++ D G L+S + I + EN+ NK
Sbjct: 2027 I-----SVRRRVRAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKGENEGLQFTNKVYNAT 2081
Query: 896 IEENSKVRI-HRETKLNGTAG 915
I+ENS I + + +G AG
Sbjct: 2082 IKENSGAGILVTKVEASGEAG 2102
Score = 97.1 bits (231), Expect = 3e-18
Identities = 119/470 (25%), Positives = 192/470 (40%), Gaps = 29/470 (6%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y L S +++ LLD NDN P F + Y+ S+ G + +V A DPD G N
Sbjct: 1840 DYGPTPLSSSTQLQLVLLDRNDNAPSFSRKS-YQASVSEGLPPGAEVLRVSAFDPDEGPN 1898
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSL 552
G V Y L S+ F ++ TG + E R + A S+
Sbjct: 1899 GRVTYSLTEDSS---QGAFSVDSLTGVIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSV 1955
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
A VT++V + ++P P WV + V + D+ + + +
Sbjct: 1956 ASVTVQV----EDVNDNVPICDQNPVNAWVSARTLPNQIVATVTAEDSDQGENGTIQFAL 2011
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
EE + F + +G I+V R + + + ++T+ + + + E
Sbjct: 2012 SDEENL-FDINRETGEISV---RRRVRAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKGE 2067
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L + + +KENS GA I + S G+ V + + ++ I
Sbjct: 2068 NEGL-QFTNKVYNATIKENS-GAGI-LVTKVEASGEAGSRQSVVYTIFSGNENSLFSIN- 2123
Query: 733 AEDGTIFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
G I QK LD E + V+A+ G+ + +V+I++ D NDN P FE +
Sbjct: 2124 HHTGEIRVQKDYALDFELSPHIHLVVLAD--NGLQTTH--CRVSIHLLDVNDNAPRFERS 2179
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
+Y + E T + + A+DAD G N Y++ G+ E F +D G++
Sbjct: 2180 SYRTAVWEGQAHNTYVMQ---MFASDADSGINGQIEYSIVSGDPNEAFILDSVRGILA-T 2235
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
LDRE YKL L A D G LSS A + + + D NDN P +E
Sbjct: 2236 SIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPAIPHME 2285
Score = 95.5 bits (227), Expect = 1e-17
Identities = 123/478 (25%), Positives = 198/478 (41%), Gaps = 45/478 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S V V ++D NDN+P +P ++ + N G + +V A D DL +
Sbjct: 2258 DPPLSSTATVRVQVVDVNDNSPA-IP-HMEPVVIAENRPAGHTVTQVTANDVDLSST--I 2313
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
Y L + N ++ SPF IN TG VS+ + E + L V ASD SL
Sbjct: 2314 RYSL--SGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTVLASD----------SLH 2361
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLL 611
+ EV + P F Y+ + T V + D + +++Y LL
Sbjct: 2362 QTSGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLL 2421
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDV 669
+G F ++ SG I + V ++ + LS V + V ++D
Sbjct: 2422 SSPLQG--FYIQADSGAIFTNKPIKATANGNLIHLLVEAKDGGDPALSSVASVDVQILDT 2479
Query: 670 NDERGVLLKGAHSPIIFHVKENSAG----AAIGQIF---HTNMSSIYGNGTGNVRFLIAN 722
ND + +S I A +A Q + +T++ G RF +
Sbjct: 2480 NDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAITQGNEERRFCLEV 2539
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDEN 781
+ V + G + LDRE D Y +TV +++ ++ + + +T+ D N
Sbjct: 2540 RL-VPIENQWRNVGKLVLCNALDRETTDSYVLTVSVSDRGDPPLNSSAVVMLTV--ADRN 2596
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD 840
DN PVF Y + E+S GT + + A D D G N+L + + G K + +D
Sbjct: 2597 DNAPVFSSTEYHAQVSESSPRGTRLVQ---VSARDPDLGANSLVRFDIISGNSKGHYKLD 2653
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE-----AELIIMIGDENDNKPEF 893
+G++ + SLD E+ Y L++ A D G S + A + I + DENDN P F
Sbjct: 2654 PESGLLA-VNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVLDENDNSPHF 2710
Score = 94.7 bits (225), Expect = 2e-17
Identities = 105/451 (23%), Positives = 186/451 (41%), Gaps = 38/451 (8%)
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKI 513
+N + + +Y ++K N+ G ++ KV+A + G V+Y + + S F I
Sbjct: 2067 ENEGLQFTNKVYNATIKENSGAGILVTKVEA-SGEAGSRQSVVYTIFSGNE---NSLFSI 2122
Query: 514 NPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
N +TG + V + L+ H V +D + R S+ ++ + +
Sbjct: 2123 NHHTGEIRVQKDYALDFELSPHIHLVVLADNGLQTTHCRVSIHLLDVN---------DNA 2173
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGV 628
P F + Y V T V Q+ +DA + Y ++ G + F ++ G+
Sbjct: 2174 PRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIVSG-DPNEAFILDSVRGI 2232
Query: 629 ITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ L R P Y A Q + LS V VVDVND + H +
Sbjct: 2233 LATSIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPAI---PHMEPVVI 2289
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDR 746
+ AG + Q+ ++ + +R+ ++ + AI + G + + LD
Sbjct: 2290 AENRPAGHTVTQVTANDVDL-----SSTIRYSLSGNSSLGSPFAINQYTGVVSLTRALDY 2344
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E++ Y +TV+A + SG +V + + D NDN PVF +Y+ ++ S++ T
Sbjct: 2345 EEQAEYTLTVLASDSLHQTSG----EVKVQVLDLNDNAPVFSEDSYQ---VDLSELATAD 2397
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ + ATD D G N Y L + F + ++G + + L +
Sbjct: 2398 TLVLSVSATDRDSGPNGEITYRLLSSPLQGFYIQADSGAIFTNKPIKATANGNLIHLLVE 2457
Query: 867 ARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
A+D G LSS A + + I D ND+ P F+Q
Sbjct: 2458 AKDGGDPALSSVASVDVQILDTNDHVPTFHQ 2488
Score = 89.4 bits (212), Expect = 7e-16
Identities = 113/456 (24%), Positives = 185/456 (40%), Gaps = 30/456 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L S V V +LD NDN PVF LY S+ ++ VG+ +V A D D G +
Sbjct: 529 EPSLSSTATVTVQVLDVNDNEPVF-QRQLYGASVPEHSAVGSCFLQVVATDADSPAFGTL 587
Query: 496 LYDLQRTSNLTITSP-FKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYS 551
LY L + P F ++P +G + V++ + H L + A D P S + Y
Sbjct: 588 LYSLSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAED-PGGLSAQTY- 645
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYD 609
V +EV + + P F Y + + G V + D + V+Y
Sbjct: 646 ---VHVEV----EDLNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYG 698
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVD 668
++ G + F V+ ++G +T+ L+ A +S TVHV+
Sbjct: 699 IIPGDMSSL-FDVDPQTGTLTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLH 757
Query: 669 VNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
V + ++ F V E++ G +G + ++ + + + R + Q
Sbjct: 758 SARAPAVFHQSRYT---FTVAEDATPGTTVGTVEAVTPAAEGFSASVSYRISSGDPQGFF 814
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G I + KPLD E + + + + + + QV I + D NDN PVF
Sbjct: 815 S--IHPRSGVISSTKPLDHELQPNVLLVIQSYSDASPVYSTT--QVNIAVTDVNDNAPVF 870
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
A+ + +N GT + I A DAD G+N Y L + F +D N G V
Sbjct: 871 LRASDAVSVSQNVLPGTVLY---IAHAHDADSGSNGRVRYRLRNDRFGTFGIDRNLGTVT 927
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
I SL ++ Y L +VA D G + + L + +
Sbjct: 928 LI-QSLLGSRQQSYHLEVVAEDGGEPAQSSGLSLSV 962
Score = 88.2 bits (209), Expect = 2e-15
Identities = 115/473 (24%), Positives = 192/473 (40%), Gaps = 38/473 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + LLD NDN P F S+ Y ++ T + ++ A D D G NG + Y +
Sbjct: 2162 VSIHLLDVNDNAPRFERSS-YRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIVSGDP 2220
Query: 505 LTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F ++ G + S+ + + L ++A+DQ P S A V ++V
Sbjct: 2221 ---NEAFILDSVRGILATSIPLDREITPSYKLVLQAADQGDPPLS---STATVRVQVV-D 2273
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P IP + N G +V Q+ ND + + Y L G PFA+
Sbjct: 2274 VNDNSPAIPHMEPVV----IAENRPAGHTVTQVTANDVDLSSTIRYSLSGNSSLGSPFAI 2329
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+ +GV+++ L + Y +A S V V+D+ND V + ++
Sbjct: 2330 NQYTGVVSLTRALDYEEQAEYTLTVLASDSLHQTS--GEVKVQVLDLNDNAPVFSEDSYQ 2387
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
+ + +A + + T+ S NG R L + Q A+ G IFT K
Sbjct: 2388 VDLSELA--TADTLVLSVSATDRDS-GPNGEITYRLLSSPLQGF---YIQADSGAIFTNK 2441
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
P+ ++ + G + + + V + I D ND+ P F Y I E++
Sbjct: 2442 PIKATANGNLIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPT 2501
Query: 803 GTEIKMDNIIKATDAD-EGTNALFMYTLF-GEGKEMFDVD------EN--TGVVKFI-GD 851
+ + A D D N Y + G + F ++ EN V K + +
Sbjct: 2502 DATLL---TLSAEDQDWSPANTHLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCN 2558
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+LDRE Y L++ D G L+S A +++ + D NDN P F+ E +++V
Sbjct: 2559 ALDRETTDSYVLTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYHAQV 2611
Score = 87.4 bits (207), Expect = 3e-15
Identities = 111/397 (27%), Positives = 163/397 (41%), Gaps = 45/397 (11%)
Query: 1001 VIVARSLPPESEF-RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V+++R E +F L I A DGG + +R+ V D ND+ PVF +T Y+ +V E
Sbjct: 184 VLMSRLDREEQDFYSLTIEAFDGGVPPRTGTLQLRIHVLDENDNPPVFNQTEYHASVPED 243
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ +V ATD D G N +TY I + SD D F I+ +GV+ VN LD E +
Sbjct: 244 APLMSPVCQVHATDLDLGDNGRITYEINRRQSDPDRVFSINRTSGVVYVNKPLDYEAQAF 303
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA--FDELLEWKHPEADELSNHNF 1173
+ L V A DNG ++ND+SP E + EA L +
Sbjct: 304 HELIVSATDNG-AQPEHSSTFVGVRVLNINDHSPSISVLFLSETGDAAVSEAAGLGDFVA 362
Query: 1174 ESVMMIPVYK-----ATIEEN---APIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
+ P ++ T+E + + T ++A + LY L R +
Sbjct: 363 RISVSDPDFQEERVAVTLEGDDGKFTLKQTADFLYALYVSADLDREEKDLYELKVRAS-- 420
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
+LG P LSS + ++ V D D P F Y + + E+V L+ L +
Sbjct: 421 DLGSPPLSSEVVFLLRVTDAND-----CHPQFEKDAYTVSVPEDVPQGSSLIQLQARDAD 475
Query: 1286 E--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
E N +RY IL N R I+P +G + DRE + +V
Sbjct: 476 EGPNGAVRYSILRSNQD---RLVSIEPESGLVATAAPLDRESLEQLWFLV---------- 522
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
VA D E V V++ DVNDN P F
Sbjct: 523 -------VAADGGEPSLSSTATVTVQVLDVNDNEPVF 552
Score = 86.6 bits (205), Expect = 5e-15
Identities = 59/185 (31%), Positives = 90/185 (48%), Gaps = 10/185 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D A + Y L+ G +LFS++ G + LD + +H F L+VQ
Sbjct: 1679 VSATDGDSEENAVVWYSLLPGPGYELFSINPDTGLITTASYLDREQQHG-----FTLRVQ 1733
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +A A V +LD NDN P F + IS+ ENLP G ++ A+D D GE
Sbjct: 1734 ARDSGPRPLSATATVLCSVLDDNDNPPAFMQSSFRISLPENLPPG-AIHTAQASDPDLGE 1792
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
NG Y + +D G F+++ RSG V VLDRE + + + A++ P+ + +
Sbjct: 1793 NGTILYSIVGEDCAGCFTVNSRSG--VVSTTKVLDREEKQNYTLTIQARDYGPTPLSSST 1850
Query: 396 DSQRI 400
Q +
Sbjct: 1851 QLQLV 1855
Score = 86.2 bits (204), Expect = 6e-15
Identities = 69/221 (31%), Positives = 105/221 (47%), Gaps = 14/221 (6%)
Query: 940 IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
IPE+ P T++ L+A D D S N + Y ++ LEV+ + N+
Sbjct: 2495 IPEDTPTDATLLTLSAEDQDWSPANTHLDYAITQG-----NEERRFCLEVRLVPIENQWR 2549
Query: 999 --GHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
G +++ +L E+ + L +S D G+ LN + V + V D ND+ PVF T Y+
Sbjct: 2550 NVGKLVLCNALDRETTDSYVLTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYHA 2609
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
V E+ L +V A D D G N+ + + I ++ +++ P +G+L+VN LD E
Sbjct: 2610 QVSESSPRGTRLVQVSARDPDLGANSLVRFDIISGNSKGHYKLDPESGLLAVNQSLDYEQ 2669
Query: 1113 EDKYILTVVARDNG--XXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ KYILTV A D G D NDNSP F
Sbjct: 2670 DPKYILTVRASDGGEFSEKHQVAFAVVFITVLDENDNSPHF 2710
Score = 85.4 bits (202), Expect = 1e-14
Identities = 153/578 (26%), Positives = 240/578 (41%), Gaps = 88/578 (15%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ---- 500
V V++LD NDN PVF +LY F++ ++G V A D D G+N + Y L
Sbjct: 1059 VTVSVLDVNDNAPVF-SRDLYYFTVSEAPSPQGLVGTVSAADKDSGRNAQLSYILLSDGK 1117
Query: 501 --RTSNLTITSPFKI--------NPN-----TGTVS--VAESPILEGRHALFVEASDQPA 543
R + T SP+++ PN +G + VA + +H L V +DQ
Sbjct: 1118 FFRINAKTGQSPWQLRCFSVAWMRPNALVSPSGEIINWVALNREHHSQHTLKVMVTDQ-G 1176
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN----- 598
+P R + A V I VT T N P FM P V + G + N
Sbjct: 1177 HP--RLNATATVHILVT-DTNDN---TPQFMHLPASKEVNVQIWAEIPAGSLVANMFAKD 1230
Query: 599 -DAFEQNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
DA E V++ L +EG P F ++ +G I + +R RP Y V +
Sbjct: 1231 LDAGENGTVTFSLA-SEDEGEPPHFEIDGETGNIRTTEHFTRNTRPFYTL-TVCASDGGA 1288
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPII--FHVKENSAGAAIGQIFHTNMSSIYGNGT 713
+ A VH V V+ V + H P++ F V+E++ A + + S
Sbjct: 1289 PPLEHVAVVH-VQVHGSEAVDGRAEH-PLVRRFTVREDAELATV-------IGSARVPDE 1339
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI-YQ 772
G R+ I+ A G I+ +PLD E Y + V AE G+ GA
Sbjct: 1340 GRFRYSISEGDGSVQFGIDASSGDIYVNQPLDYEAAAQYVLVVRAE-GAGLAPGANASVL 1398
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLF 830
V++ +ED ND+ P F + E++ +G+ + +A DAD GT N+ Y L
Sbjct: 1399 VSVMVEDANDHTPWFPDKMVLLGLSEDATVGS---LAFAFQARDAD-GTFPNSAVRYGLT 1454
Query: 831 GEGKEM-------FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--- 880
+ K F ++ TG + + LDRE + ++ A D E +
Sbjct: 1455 YDPKVTDSSTRFPFQMNPYTGSLT-VTAPLDRETTSSFAFTVTATDQARRKEERKQATVA 1513
Query: 881 --IMIGDENDNKPEF-----NQIEENSKV--RIHR------ETKLNGTAGFTIIEVKPKN 925
+ + D NDN+P F Q+ E+++V +HR + NG +TI+ K
Sbjct: 1514 AQVFLLDVNDNRPVFISAVSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKG 1573
Query: 926 KFALDVDQ-LGPLFLIPENIPIGTTIIKLNALDLDSGL 962
F L+ + PLF + P+ +++ L+ L GL
Sbjct: 1574 MFTLEGNTGKMPLFCLH---PLCFSVLNLSCLHFSPGL 1608
Score = 85.0 bits (201), Expect = 1e-14
Identities = 54/164 (32%), Positives = 83/164 (50%), Gaps = 10/164 (6%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
+ G ++ Y + SGN+ LFS++ G + ++K+ LD E + + VL +N
Sbjct: 2100 EAGSRQSVVYTIFSGNENSLFSINHHTGEIRVQKDYALDFELSPHIHLVVLA------DN 2153
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
L+T RV I LLD+NDN P FE Y ++ E + V+Q+ A+D D G NG+ Y
Sbjct: 2154 GLQTTHCRVSIHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEY 2213
Query: 344 QL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ DP AF +D G L LDRE S ++ + A +
Sbjct: 2214 SIVSGDPNEAFILDSVRGILA--TSIPLDREITPSYKLVLQAAD 2255
Score = 83.4 bits (197), Expect = 4e-14
Identities = 65/214 (30%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN+P G I A D D G NG I Y E + F +N R G
Sbjct: 1771 LPENLPPGA-IHTAQASDPDLGENGTILYSIVGE-------------DCAGCFTVNSRSG 1816
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V + L E + + L I A D G L+ + +++ + D ND+ P F + Y +V
Sbjct: 1817 VVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLLDRNDNAPSFSRKSYQASVS 1876
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V A D D G N +TY + + F + LTGV+ G LDRE+ +
Sbjct: 1877 EGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLTGVIRTTGPLDRESRAQ 1936
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
Y L VA D DVNDN P
Sbjct: 1937 YTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVP 1970
Score = 83.0 bits (196), Expect = 6e-14
Identities = 114/464 (24%), Positives = 192/464 (41%), Gaps = 29/464 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + DAND +P F + Y S+ + G+ + +++A D D G NG V Y
Sbjct: 427 LSSEVVFLLRVTDANDCHPQF-EKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYS 485
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLAVVTI 557
+ R++ + S I P +G V+ A E L F+ + PS S A VT+
Sbjct: 486 ILRSNQDRLVS---IEPESGLVATAAPLDRESLEQLWFLVVAADGGEPSLS--STATVTV 540
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHGYE 615
+V N+P F Y V + +G+ Q+ DA + Y L G++
Sbjct: 541 QVL-DVNDNEPV---FQRQLYGASVPEHSAVGSCFLQVVATDADSPAFGTLLYSLSDGFD 596
Query: 616 ---EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
+ F V +SG + V D+ R + + ++ LS T V V D+ND
Sbjct: 597 GQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPGGLSAQTYVHVEVEDLNDN 656
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIA 731
V ++ I + GA + + T+ S G V + +I D+
Sbjct: 657 APVFNPDEYTVSISGHAQ--PGAEVLNVIATDRDS---GRFGQVTYGIIPGDMSSLFDVD 711
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ GT+ PL ++ + A+ +GV+S VT+++ P VF +
Sbjct: 712 -PQTGTLTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAV-VTVHVLHSARAPAVFHQSR 769
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIG 850
Y + E++ GT + + T A EG +A Y + G+ + F + +GV+
Sbjct: 770 YTFTVAEDATPGTTV--GTVEAVTPAAEGFSASVSYRISSGDPQGFFSIHPRSGVISST- 826
Query: 851 DSLDREKKIMYKLSLVA-RDTGGLSSEAELIIMIGDENDNKPEF 893
LD E + L + + D + S ++ I + D NDN P F
Sbjct: 827 KPLDHELQPNVLLVIQSYSDASPVYSTTQVNIAVTDVNDNAPVF 870
Score = 80.6 bits (190), Expect = 3e-13
Identities = 88/332 (26%), Positives = 144/332 (43%), Gaps = 30/332 (9%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGL 138
L + +++ D NDN P+F T YH +V E P + G + I + R
Sbjct: 215 LQLRIHVLDENDNPPVFNQTEYHASVPEDAPLMSPVCQVHATDLDLGDNGRITYEINRRQ 274
Query: 139 TIFKDIRAFDR-------DKPNTPNSDV-HYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
+ + + +R +KP + H IVS D+G + H + +VL+
Sbjct: 275 SDPDRVFSINRTSGVVYVNKPLDYEAQAFHELIVSATDNG---AQPEHSSTFVGVRVLNI 331
Query: 191 DAGDKEFQLVIMA-SGKRIHKEIL----FPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
+ ++ ++ +G E F I D D + G+D K F+
Sbjct: 332 NDHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQEERVA--VTLEGDDGK-FT 388
Query: 246 LDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
L L+ L DLD E + + + L+V+AS L +P +++ + + D ND P
Sbjct: 389 LKQTADFLYALYVSADLDRE---EKDLYELKVRASDLGSPPLSSEVVFLLRVTDANDCHP 445
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
+FE D Y +S+ E++P G S++Q+ A D D+G NG Y + + SI+P SG
Sbjct: 446 QFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYSILRSNQDRLVSIEPESG--L 503
Query: 363 VRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
V LDRE+ L V A + PS+ T
Sbjct: 504 VATAAPLDRESLEQLWFLVVAADGGEPSLSST 535
Score = 80.6 bits (190), Expect = 3e-13
Identities = 100/371 (26%), Positives = 159/371 (42%), Gaps = 34/371 (9%)
Query: 52 VVKFRLGCDFDEGDDL---VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE 108
VV D++E + V L+Q S V V + D+NDN P+F + Y V + E
Sbjct: 2335 VVSLTRALDYEEQAEYTLTVLASDSLHQTSG--EVKVQVLDLNDNAPVFSEDSYQVDLSE 2392
Query: 109 LTPTGEKAFIFLIAP---IGPSLTIP---LTVP-RGLTIFKDIRAFDRDKP--NTPNSDV 159
L T + + + A GP+ I L+ P +G I D A +KP T N ++
Sbjct: 2393 LA-TADTLVLSVSATDRDSGPNGEITYRLLSSPLQGFYIQADSGAIFTNKPIKATANGNL 2451
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPI 218
+ +V D G AL S + + D+ +E + + +L +
Sbjct: 2452 IHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLL---TL 2508
Query: 219 HAIDQDLGVGAT-LRYELISGNDRKLFSLDS-----VNGSLFLEKELDLDAEHNLQANTF 272
A DQD T L Y + GN+ + F L+ N + K + +A +++
Sbjct: 2509 SAEDQDWSPANTHLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSY 2568
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VL V S +P + A V + + D NDN P F Y+ + E+ P G ++QV A D
Sbjct: 2569 VLTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARD 2628
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
D G N + + + KG + +DP SG L V NQ+ LD E + V A +
Sbjct: 2629 PDLGANSLVRFDIISGNSKGHYKLDPESGLLAV-NQS-LDYEQDPKYILTVRASDG---- 2682
Query: 391 VGTFADSQRIA 401
G F++ ++A
Sbjct: 2683 -GEFSEKHQVA 2692
Score = 80.2 bits (189), Expect = 4e-13
Identities = 57/171 (33%), Positives = 85/171 (49%), Gaps = 20/171 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLG + +R+++ISGN + + LD +G L + + LD + Q ++L V+
Sbjct: 2624 VSARDPDLGANSLVRFDIISGNSKGHYKLDPESGLLAVNQSLDYE-----QDPKYILTVR 2678
Query: 278 AS---QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
AS + + + A A V I +LD NDN P F N S++ENLP V A D D
Sbjct: 2679 ASDGGEFSEKHQVAFAVVFITVLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDND 2738
Query: 335 QGENGEFTYQLDDP------------KGAFSIDPRSGWLTVRNQTVLDREA 373
G G+ TY + P K AF+IDP +G + R +RE+
Sbjct: 2739 LGSYGQLTYSILSPCFLDYDSGSPEKKEAFAIDPLTGDVHTRQTFDYERES 2789
Score = 79.0 bits (186), Expect = 9e-13
Identities = 83/307 (27%), Positives = 134/307 (43%), Gaps = 26/307 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G +S+ + + + D ND P F Y V+V E P G A GP+ +
Sbjct: 423 GSPPLSSEVVFLLRVTDANDCHPQFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAV 482
Query: 131 PLTVPRG-----LTIFKDIRAFDRDKPNTPNS-DVHYSIVSGNDDGHFALESSHKPVLLL 184
++ R ++I + P S + + +V D G +L S+ +
Sbjct: 483 RYSILRSNQDRLVSIEPESGLVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTV-- 540
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEI--LFPEPIHAIDQDLGVGATLRYELISGNDRK 242
+VLD + + FQ + + H + F + + A D D TL Y L G D +
Sbjct: 541 -QVLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVV-ATDADSPAFGTLLYSLSDGFDGQ 598
Query: 243 ----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
LF + +G L + +++D D+ + L ++A +AQ V +E+ D
Sbjct: 599 DQHPLFHVHPQSGELCVSQDIDRDSGQTVHD----LLIRAEDPGG--LSAQTYVHVEVED 652
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDP 356
LNDN P F D Y +SI + G VL V+ATD+D G G+ TY + D F +DP
Sbjct: 653 LNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYGIIPGDMSSLFDVDP 712
Query: 357 RSGWLTV 363
++G LT+
Sbjct: 713 QTGTLTL 719
Score = 78.2 bits (184), Expect = 2e-12
Identities = 108/420 (25%), Positives = 179/420 (42%), Gaps = 47/420 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ P+ + + +++A DLD G NG+I YE N P R F IN G
Sbjct: 240 VPEDAPLMSPVCQVHATDLDLGDNGRITYEINRRQSDP-----------DRVFSINRTSG 288
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNIS--VRVFVKDVNDHFP----VFKKTWYN 1051
V V + L E++ L +SA D G ++ S V V V ++NDH P +F +
Sbjct: 289 VVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVGVRVLNINDHSPSISVLFLSETGD 348
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF-EISPLTGVLSVNGELDR 1110
V EA + ++ +D DF Q + ++ D + + L V+ +LDR
Sbjct: 349 AAVSEAAGLGDFVARISVSDPDF-QEERVAVTLEGDDGKFTLKQTADFLYALYVSADLDR 407
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E +D Y L V A D G D ND P+F + PE +
Sbjct: 408 EEKDLYELKVRASDLG-SPPLSSEVVFLLRVTDANDCHPQFE--KDAYTVSVPEDVPQGS 464
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNL-- 1227
S++ + A N + ++ + + I +GL+ + P R++ + L
Sbjct: 465 ----SLIQLQARDADEGPNGAVRYSILRSNQDRLVSIEPESGLVATAAPLDRESLEQLWF 520
Query: 1228 -------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
G PSLSSTA + V V DV D ++PVF + Y + E+ + +
Sbjct: 521 LVVAADGGEPSLSSTATVTVQVLDVND-----NEPVFQRQLYGASVPEHSAVGSCFLQVV 575
Query: 1281 LTE-HYENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDREVKDT-YEVIVRAE 1336
T+ F Y L++ + D F + P++G L + + DR+ T +++++RAE
Sbjct: 576 ATDADSPAFGTLLYSLSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAE 635
Score = 77.4 bits (182), Expect = 3e-12
Identities = 113/414 (27%), Positives = 177/414 (42%), Gaps = 62/414 (14%)
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
T ++++ A D DSG+NGQI Y S +S D E F+++ G I+A S+
Sbjct: 2193 TYVMQMFASDADSGINGQIEY----------SIVSGDPNEA---FILDSVRG--ILATSI 2237
Query: 1008 PPESE----FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
P + E ++L + A D G+ L+ +VRV V DVND+ P + E +
Sbjct: 2238 PLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPAIPH-MEPVVIAENRPAG 2296
Query: 1062 RVLGKVDATDADFGQNANLTYFIQ-PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
+ +V A D D ++ + Y + S PF I+ TGV+S+ LD E + +Y LTV
Sbjct: 2297 HTVTQVTANDVDL--SSTIRYSLSGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTV 2354
Query: 1121 VARDNGXXXXXXXXXXXXXXXXDVNDNSPKF----YAFD-------ELLEWKHPEADELS 1169
+A D+ D+NDN+P F Y D + L D S
Sbjct: 2355 LASDS----LHQTSGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDS 2410
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL 1229
N E + ++ + I +F N NG +++ L + K+ G
Sbjct: 2411 GPNGEITYRL---LSSPLQGFYIQADSGAIFTN-KPIKATANGNLIHLLVEAKDG---GD 2463
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH---YE 1286
P+LSS A + V + D D V P F Y L I E+ L++L+ +
Sbjct: 2464 PALSSVASVDVQILDTNDHV-----PTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPA 2518
Query: 1287 NFKMRYYILNEND-----TDIRRTFVIDP-RN-GTLYLVRSPDREVKDTYEVIV 1333
N + Y I N+ ++R + + RN G L L + DRE D+Y + V
Sbjct: 2519 NTHLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVLTV 2572
Score = 74.5 bits (175), Expect = 2e-11
Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 10/156 (6%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE++D Y +T+ A F+ GV G Q+ I++ DENDNPPVF Y + E++ +
Sbjct: 189 LDREEQDFYSLTIEA-FDGGVPPRTGTLQLRIHVLDENDNPPVFNQTEYHASVPEDAPLM 247
Query: 804 TEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
+ + + ATD D G N Y + + +F ++ +GVV ++ LD E +
Sbjct: 248 SPVCQ---VHATDLDLGDNGRITYEINRRQSDPDRVFSINRTSGVV-YVNKPLDYEAQAF 303
Query: 861 YKLSLVARDTGGLSSEAELI--IMIGDENDNKPEFN 894
++L + A D G + + + + ND+ P +
Sbjct: 304 HELIVSATDNGAQPEHSSTFVGVRVLNINDHSPSIS 339
Score = 74.5 bits (175), Expect = 2e-11
Identities = 68/221 (30%), Positives = 101/221 (45%), Gaps = 25/221 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++P G+++I+L A D D G NG +RY + + D R I G
Sbjct: 456 VPEDVPQGSSLIQLQARDADEGPNGAVRYSI--------LRSNQD-----RLVSIEPESG 502
Query: 1000 HVIVARSLPPESEFRL--NISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V A L ES +L + A DGG +L+ +V V V DVND+ PVF++ Y +V
Sbjct: 503 LVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGASVP 562
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQP----SDTDLPFEISPLTGVLSVNGELDRE 1111
E +V ATDAD L Y + D F + P +G L V+ ++DR+
Sbjct: 563 EHSAVGSCFLQVVATDADSPAFGTLLYSLSDGFDGQDQHPLFHVHPQSGELCVSQDIDRD 622
Query: 1112 T-EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ + + L + A D G D+NDN+P F
Sbjct: 623 SGQTVHDLLIRAEDPG---GLSAQTYVHVEVEDLNDNAPVF 660
Score = 72.9 bits (171), Expect = 6e-11
Identities = 73/299 (24%), Positives = 128/299 (42%), Gaps = 18/299 (6%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISAL---DGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
F IN G + V + + E +I + D G + V + + DVND+ P F+++
Sbjct: 2120 FSINHHTGEIRVQKDYALDFELSPHIHLVVLADNGLQTTHCRVSIHLLDVNDNAPRFERS 2179
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
Y V E Q + ++ A+DAD G N + Y I D + F + + G+L+ + L
Sbjct: 2180 SYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIVSGDPNEAFILDSVRGILATSIPL 2239
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE-LLEWKHPEADE 1167
DRE Y L + A D G DVNDNSP + ++ P
Sbjct: 2240 DREITPSYKLVLQAADQG-DPPLSSTATVRVQVVDVNDNSPAIPHMEPVVIAENRPAGHT 2298
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQN 1226
++ V + + ++ N+ +G+ A I G++ L + Q
Sbjct: 2299 VTQVTANDVDLSSTIRYSLSGNSSLGSPFA---------INQYTGVVSLTRALDYEEQAE 2349
Query: 1227 LGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEENVNAPVELVSLNLTE 1283
L L+S + L T +V +V +++D PVF Y++++ E A ++S++ T+
Sbjct: 2350 YTLTVLASDS-LHQTSGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLSVSATD 2407
Score = 72.1 bits (169), Expect = 1e-10
Identities = 81/296 (27%), Positives = 126/296 (42%), Gaps = 31/296 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE--LTPTGEKAFIFLIAPIGPSLTIPLTV- 134
+ + V++++ DVNDN P F + Y V E T A G + I ++
Sbjct: 2157 TTHCRVSIHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIV 2216
Query: 135 ---PRGLTIFKDIR-----AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
P I +R + D+ TP+ + ++ D G L S+ + +
Sbjct: 2217 SGDPNEAFILDSVRGILATSIPLDREITPSYKL---VLQAADQGDPPLSSTATVRVQVVD 2273
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR--KLF 244
V D + V++A + + + A D DL +T+RY L SGN F
Sbjct: 2274 VNDNSPAIPHMEPVVIAENRPAGHTVT---QVTANDVDLS--STIRYSL-SGNSSLGSPF 2327
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+++ G + L + LD + + + L V AS + L V++++LDLNDN P
Sbjct: 2328 AINQYTGVVSLTRALDYEEQAE-----YTLTVLAS---DSLHQTSGEVKVQVLDLNDNAP 2379
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSG 359
F D Y + + E VL V ATD+D G NGE TY+ L P F I SG
Sbjct: 2380 VFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQGFYIQADSG 2435
Score = 71.7 bits (168), Expect = 1e-10
Identities = 86/332 (25%), Positives = 144/332 (43%), Gaps = 26/332 (7%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-IGPSLTI 130
+G +SA +V + D NDN P F+ + + +++ E P G P +G + TI
Sbjct: 1737 SGPRPLSATATVLCSVLDDNDNPPAFMQSSFRISLPENLPPGAIHTAQASDPDLGENGTI 1796
Query: 131 PLTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
++ T+ K +Y++ + D G L SS + L+L
Sbjct: 1797 LYSIVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVL 1856
Query: 185 RKVLDY--DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
D K +Q + + G E+L + A D D G + Y L + +
Sbjct: 1857 LDRNDNAPSFSRKSYQASV-SEGLPPGAEVL---RVSAFDPDEGPNGRVTYSLTEDSSQG 1912
Query: 243 LFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
FS+DS+ G + LD + A++ L+A V +Q PL T+ A V +++ D+N
Sbjct: 1913 AFSVDSLTGVIRTTGPLDRESRAQYTLRA---VATDGCTQ--GPL-TSVASVTVQVEDVN 1966
Query: 301 DNLPEFEVDFYNISI-VENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
DN+P + + N + LPN V V A D DQGENG + L D + F I+ +G
Sbjct: 1967 DNVPICDQNPVNAWVSARTLPNQI-VATVTAEDSDQGENGTIQFALSDEENLFDINRETG 2025
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
++VR + R S +++V + V+
Sbjct: 2026 EISVRRRV---RAGFSGRKLEVMVSDRGRPVL 2054
Score = 69.3 bits (162), Expect = 8e-10
Identities = 61/235 (25%), Positives = 100/235 (42%), Gaps = 17/235 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
++V N + + + P+ +I EN P G T+ ++ A D+D L+ IRY +
Sbjct: 2269 VQVVDVNDNSPAIPHMEPV-VIAENRPAGHTVTQVTANDVD--LSSTIRYSLSGN----- 2320
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNIS-VRVFVKD 1037
S L + F IN+ G V + R+L E + ++ L +L+ V+V V D
Sbjct: 2321 SSLGSP-------FAINQYTGVVSLTRALDYEEQAEYTLTVLASDSLHQTSGEVKVQVLD 2373
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
+ND+ PVF + Y ++ E ++ V ATD D G N +TY + S F I
Sbjct: 2374 LNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQ-GFYIQA 2432
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
+G + N + I +V +G D ND+ P F+
Sbjct: 2433 DSGAIFTNKPIKATANGNLIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFH 2487
Score = 68.9 bits (161), Expect = 1e-09
Identities = 112/478 (23%), Positives = 190/478 (39%), Gaps = 58/478 (12%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL-GQNGMVLYDLQRTSNLTITSPFKINP 515
P + Y F++ +A GT +G V+AV P G + V Y R S+ F I+P
Sbjct: 762 PAVFHQSRYTFTVAEDATPGTTVGTVEAVTPAAEGFSASVSY---RISSGDPQGFFSIHP 818
Query: 516 NTGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
+G +S + E + + L V S A+P YS V I VT + P F+
Sbjct: 819 RSGVISSTKPLDHELQPNVLLVIQSYSDASPV---YSTTQVNIAVT----DVNDNAPVFL 871
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGVITVV 632
A V NV GT + +DA ++ V Y L + + F ++ G +T++
Sbjct: 872 RASDAVSVSQNVLPGTVLYIAHAHDADSGSNGRVRYRLRN--DRFGTFGIDRNLGTVTLI 929
Query: 633 DDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
L + Y E VA E+ ++ V V D A +++ V+
Sbjct: 930 QSLLGSRQQSYHLEVVA--EDGGEPAQSSGLSLSVSV-DRSAAEDSLAFETLVYQVEIGE 986
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY 752
++ G+G+ + + V+D + + LD E + +
Sbjct: 987 GYRKDSRVIQLGPRLRLGDGSR------LSSRSVSDSSQVR---VVVLAHSLDYETQSAF 1037
Query: 753 RMTVIAEFNKGVISGA-GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
R V+A + ++ VT+ + D NDN PVF Y + S+ + +
Sbjct: 1038 RFRVLASAAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTV---SEAPSPQGLVGT 1094
Query: 812 IKATDADEGTNALFMYTLFGEGKEMFDVDENTG------------------VVKFIGD-- 851
+ A D D G NA Y L +GK F ++ TG +V G+
Sbjct: 1095 VSAADKDSGRNAQLSYILLSDGK-FFRINAKTGQSPWQLRCFSVAWMRPNALVSPSGEII 1153
Query: 852 ---SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
+L+RE + L ++ D G L++ A + I++ D NDN P+F + + +V +
Sbjct: 1154 NWVALNREHHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTPQFMHLPASKEVNV 1211
Score = 68.1 bits (159), Expect = 2e-09
Identities = 48/168 (28%), Positives = 83/168 (49%), Gaps = 9/168 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G+ + Y ++SG+ + F LDSV G L + LD E ++ L +QA+
Sbjct: 2200 ASDADSGINGQIEYSIVSGDPNEAFILDSVRG--ILATSIPLDRE---ITPSYKLVLQAA 2254
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ A V ++++D+NDN P + I EN P G +V QV A D D
Sbjct: 2255 DQGDPPLSSTATVRVQVVDVNDNSPAIP-HMEPVVIAENRPAGHTVTQVTANDVDLSSTI 2313
Query: 340 EFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
++ + G+ F+I+ +G +++ LD E + + V A ++
Sbjct: 2314 RYSLSGNSSLGSPFAINQYTGVVSLTR--ALDYEEQAEYTLTVLASDS 2359
Score = 67.3 bits (157), Expect = 3e-09
Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 13/162 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G +RY ++ N +L S++ +G + LD ++ L+ F+ V
Sbjct: 469 LQARDADEGPNGAVRYSILRSNQDRLVSIEPESGLVATAAPLDRES---LEQLWFL--VV 523
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P ++ A V +++LD+NDN P F+ Y S+ E+ G LQV+ATD D
Sbjct: 524 AADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVVATDADSPA 583
Query: 338 NGEFTYQL------DDPKGAFSIDPRSGWLTVRNQTVLDREA 373
G Y L D F + P+SG L V +DR++
Sbjct: 584 FGTLLYSLSDGFDGQDQHPLFHVHPQSGELCVSQD--IDRDS 623
Score = 66.9 bits (156), Expect = 4e-09
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 7/182 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL---QANTFVLQV 276
A D+D T Y + + F LD LDL L + + + L +
Sbjct: 142 AKDEDEDEFGTQGYRIRESEMEERFHLDHHRSGSGQHLSLDLVLMSRLDREEQDFYSLTI 201
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+A P +T ++ I +LD NDN P F Y+ S+ E+ P V QV ATD D G
Sbjct: 202 EAFDGGVPPRTGTLQLRIHVLDENDNPPVFNQTEYHASVPEDAPLMSPVCQVHATDLDLG 261
Query: 337 ENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
+NG TY+++ DP FSI+ SG + V + +A L + P
Sbjct: 262 DNGRITYEINRRQSDPDRVFSINRTSGVVYVNKPLDYEAQAFHELIVSATDNGAQPEHSS 321
Query: 393 TF 394
TF
Sbjct: 322 TF 323
Score = 65.7 bits (153), Expect = 9e-09
Identities = 50/173 (28%), Positives = 82/173 (47%), Gaps = 14/173 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ +G+ +++ A D DS G + Y + D + F ++ + G
Sbjct: 561 VPEHSAVGSCFLQVVATDADSPAFGTLLYSLSD---------GFDGQDQHPLFHVHPQSG 611
Query: 1000 HVIVARSLPPESEFRLN---ISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE- 1055
+ V++ + +S ++ I A D G L+ V V V+D+ND+ PVF Y ++
Sbjct: 612 ELCVSQDIDRDSGQTVHDLLIRAEDPGGLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISG 671
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
AQ VL V ATD D G+ +TY I P D F++ P TG L++ L
Sbjct: 672 HAQPGAEVL-NVIATDRDSGRFGQVTYGIIPGDMSSLFDVDPQTGTLTLTSPL 723
Score = 64.9 bits (151), Expect = 2e-08
Identities = 46/140 (32%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G LFL LD +++ + L V+A P ++ +E+ D+ND P F
Sbjct: 1607 GLLFLASALDYESQRLHR-----LIVEAVDHGLPSLSSTQTFTVEVADVNDQPPVFSQSV 1661
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTV 368
YN S+ EN G V +V ATD D EN Y L G FSI+P +G +T +
Sbjct: 1662 YNASVAENKDPGEPVARVSATDGDSEENAVVWYSLLPGPGYELFSINPDTGLIT--TASY 1719
Query: 369 LDREAHSSLRMKVYAKETNP 388
LDRE ++V A+++ P
Sbjct: 1720 LDREQQHGFTLRVQARDSGP 1739
Score = 64.5 bits (150), Expect = 2e-08
Identities = 113/484 (23%), Positives = 188/484 (38%), Gaps = 58/484 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V+V +LD NDN PVF + Y+ + A T++ V A D D G NG + Y L +
Sbjct: 2367 VKVQVLDLNDNAPVFSEDS-YQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSP- 2424
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHA----LFVEASDQPANPSERRYSLAVVTIEVT 560
F I ++G + PI + L VEA D +P+ S+A V +++
Sbjct: 2425 ---LQGFYIQADSGAI-FTNKPIKATANGNLIHLLVEAKDG-GDPALS--SVASVDVQIL 2477
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGYEEG 617
+P F Y + + ++ + D + + Y + G EE
Sbjct: 2478 ----DTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAITQGNEER 2533
Query: 618 --------VPFAVEERS-GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--V 666
VP + R+ G + + + L R Y V++ + + + ++A V V
Sbjct: 2534 RFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVL-TVSVSDRGDPPLNSSAVVMLTV 2592
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND V S +H + + + ++ + VRF I +
Sbjct: 2593 ADRNDNAPVF-----SSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLVRFDIISGNSK 2647
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA----EFNKGVISGAGIYQVTIYIEDEND 782
E G + + LD E+ Y +TV A EF++ + +T+ DEND
Sbjct: 2648 GHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVL--DEND 2705
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----------- 831
N P F +T ++EN T + A D D G+ Y++
Sbjct: 2706 NSPHFVFSTVNCSVLENLPAFTHTCS---VHAVDNDLGSYGQLTYSILSPCFLDYDSGSP 2762
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
E KE F +D TG V + D E++ Y + ARD GG ++ + + I ++ P
Sbjct: 2763 EKKEAFAIDPLTGDV-HTRQTFDYERESEYCFVVEARDKGGKTATVRVQVSIRGVDEFSP 2821
Query: 892 EFNQ 895
F Q
Sbjct: 2822 IFTQ 2825
Score = 64.1 bits (149), Expect = 3e-08
Identities = 62/217 (28%), Positives = 89/217 (41%), Gaps = 25/217 (11%)
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
T ++ ++A D DSG NG+I Y S S L ++ + + +L
Sbjct: 2398 TLVLSVSATDRDSGPNGEITYRLLS------SPLQGFYIQADSGAIFTNKPIKATANGNL 2451
Query: 1008 PPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
L + A DGG+ L+ SV V + D NDH P F + Y+ + E T L
Sbjct: 2452 -----IHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLL 2506
Query: 1066 KVDATDADFG-QNANLTYFIQPSDTD----LPFEISPL------TGVLSVNGELDRETED 1114
+ A D D+ N +L Y I + + L + P+ G L + LDRET D
Sbjct: 2507 TLSAEDQDWSPANTHLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTD 2566
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y+LTV D G D NDN+P F
Sbjct: 2567 SYVLTVSVSDRG-DPPLNSSAVVMLTVADRNDNAPVF 2602
Score = 62.5 bits (145), Expect = 9e-08
Identities = 48/161 (29%), Positives = 76/161 (47%), Gaps = 9/161 (5%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
G A++ Y + SG+ + FS+ +G + K LD H LQ N ++ S +
Sbjct: 796 GFSASVSYRISSGDPQGFFSIHPRSGVISSTKPLD----HELQPNVLLVIQSYSDASPVY 851
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
T Q V I + D+NDN P F +S+ +N+ G + A D D G NG Y+L
Sbjct: 852 STTQ--VNIAVTDVNDNAPVFLRASDAVSVSQNVLPGTVLYIAHAHDADSGSNGRVRYRL 909
Query: 346 -DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+D G F ID G +T+ + R+ S ++V A++
Sbjct: 910 RNDRFGTFGIDRNLGTVTLIQSLLGSRQ--QSYHLEVVAED 948
Score = 62.1 bits (144), Expect = 1e-07
Identities = 74/329 (22%), Positives = 127/329 (38%), Gaps = 30/329 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V + + D NDN P+F T YH V E +P G + + ++ P L V +
Sbjct: 2588 VMLTVADRNDNAPVFSSTEYHAQVSESSPRGTR--LVQVSARDPDLGANSLVRFDIISGN 2645
Query: 143 DIRAFDRDKPN---TPNSDVHYS-------IVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+ D + N + Y V +D G F+ + ++ VLD +
Sbjct: 2646 SKGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVLDEND 2705
Query: 193 GDKEFQL-VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS--------GNDRK- 242
F + S +HA+D DLG L Y ++S G+ K
Sbjct: 2706 NSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDSGSPEKK 2765
Query: 243 -LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F++D + G + + D + E + + V+A KTA RV++ + +++
Sbjct: 2766 EAFAIDPLTGDVHTRQTFDYERE-----SEYCFVVEARDKGG--KTATVRVQVSIRGVDE 2818
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL 361
P F Y+ + + G V VMA D D+G +G Y L FS++ +G +
Sbjct: 2819 FSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSLVSSSPFFSVNKTTGSV 2878
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSV 390
V R +H +K+ +P +
Sbjct: 2879 FVSEPVYRRRGSHGEDLVKLLVSAGSPKL 2907
Score = 59.7 bits (138), Expect = 6e-07
Identities = 62/193 (32%), Positives = 90/193 (46%), Gaps = 21/193 (10%)
Query: 721 ANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ DV D+ I A+ G I T LDRE R Y +F +G I +V I ++D
Sbjct: 58 SRDSDVFRDLEIDADTGLISTAVVLDRESRRQY------DFVAATPTGEMI-KVRIEVKD 110
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEGKEMFD 838
ND+ PVF I E S G+ K++ K D DE GT + E +E F
Sbjct: 111 VNDHSPVFPSEGLNLEISEVSPPGSRFKLEG-AKDEDEDEFGTQGYRIRE--SEMEERFH 167
Query: 839 VD-------ENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
+D ++ + + LDRE++ Y L++ A D G + +L I + DENDN
Sbjct: 168 LDHHRSGSGQHLSLDLVLMSRLDREEQDFYSLTIEAFDGGVPPRTGTLQLRIHVLDENDN 227
Query: 890 KPEFNQIEENSKV 902
P FNQ E ++ V
Sbjct: 228 PPVFNQTEYHASV 240
Score = 58.8 bits (136), Expect = 1e-06
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 19/219 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S V +T+ D NDN PVF S Y + ++ GT + +V A DPDLG N +V
Sbjct: 2579 DPPLNSSAVVMLTVADRNDNAPVF-SSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLV 2637
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
+D+ ++ +K++P +G ++V +S E ++ L V ASD + + + A
Sbjct: 2638 RFDIISGNS---KGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFA 2694
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
VV I V + P F+ + V N+ T + ND ++Y +L
Sbjct: 2695 VVFITVL----DENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSIL 2750
Query: 612 H----GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE 646
Y+ G P +E + + D+ + R +D+E
Sbjct: 2751 SPCFLDYDSGSP-EKKEAFAIDPLTGDV--HTRQTFDYE 2786
Score = 58.4 bits (135), Expect = 1e-06
Identities = 59/204 (28%), Positives = 90/204 (44%), Gaps = 30/204 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P GT +++++A D D G N +R++ +S ++ K ++ ++ G
Sbjct: 2611 VSESSPRGTRLVQVSARDPDLGANSLVRFDI----------ISGNS---KGHYKLDPESG 2657
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVR-----VFVKDVNDHFPVFKKTWYNF 1052
+ V +SL E + + L + A DGG ++ V + V D ND+ P F + N
Sbjct: 2658 LLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVLDENDNSPHFVFSTVNC 2717
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPS----DTDLP-----FEISPLTGVL 1102
+V E V A D D G LTY I P D+ P F I PLTG +
Sbjct: 2718 SVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDSGSPEKKEAFAIDPLTGDV 2777
Query: 1103 SVNGELDRETEDKYILTVVARDNG 1126
D E E +Y V ARD G
Sbjct: 2778 HTRQTFDYERESEYCFVVEARDKG 2801
Score = 57.6 bits (133), Expect = 2e-06
Identities = 57/181 (31%), Positives = 82/181 (45%), Gaps = 33/181 (18%)
Query: 1001 VIVARSLPPESE----FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
V++A SL E++ FR+ SA + N +V V V DVND+ PVF + Y F V
Sbjct: 1023 VVLAHSLDYETQSAFRFRVLASAAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTV 1082
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-------------- 1100
EA + ++G V A D D G+NA L+Y + SD F I+ TG
Sbjct: 1083 SEAPSPQGLVGTVSAADKDSGRNAQLSYILL-SDGKF-FRINAKTGQSPWQLRCFSVAWM 1140
Query: 1101 ----VLSVNGE------LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
++S +GE L+RE ++ L V+ D G D NDN+P+
Sbjct: 1141 RPNALVSPSGEIINWVALNREHHSQHTLKVMVTDQG-HPRLNATATVHILVTDTNDNTPQ 1199
Query: 1151 F 1151
F
Sbjct: 1200 F 1200
Score = 57.6 bits (133), Expect = 2e-06
Identities = 48/170 (28%), Positives = 79/170 (46%), Gaps = 20/170 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E +P G +++++A D D G NG++ Y + S A F ++ G
Sbjct: 1875 VSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTED-----SSQGA--------FSVDSLTG 1921
Query: 1000 HVIVARSLPPES--EFRLNISALDG---GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ L ES ++ L A DG G L SV V V+DVND+ P+ + N V
Sbjct: 1922 VIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQNPVNAWV 1981
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
+++ V A D+D G+N + + + SD + F+I+ TG +SV
Sbjct: 1982 SARTLPNQIVATVTAEDSDQGENGTIQFAL--SDEENLFDINRETGEISV 2029
Score = 54.0 bits (124), Expect = 3e-05
Identities = 44/166 (26%), Positives = 76/166 (45%), Gaps = 7/166 (4%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN+P T ++A+D D G GQ+ Y S ++ + + E K F I+ G V
Sbjct: 2721 ENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLD---YDSGSPEKKEAFAIDPLTGDV 2777
Query: 1002 IVARSLP--PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
++ ESE+ + A D G + V+V ++ V++ P+F + Y+F +
Sbjct: 2778 HTRQTFDYERESEYCFVVEARDKGGKTATVRVQVSIRGVDEFSPIFTQKQYHFLLPGHSK 2837
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
V+G V A D D G + + Y + S F ++ TG + V+
Sbjct: 2838 PGDVVGFVMAMDHDRGVDGIVGYSLVSSSPF--FSVNKTTGSVFVS 2881
Score = 53.2 bits (122), Expect = 5e-05
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 19/193 (9%)
Query: 953 LNALDLDSGLNGQIRY---------EFNSEVYIPPSKLSADALEVKRYFVINERHGHVI- 1002
++A D DSG N Q+ Y N++ P +L ++ R + G +I
Sbjct: 1095 VSAADKDSGRNAQLSYILLSDGKFFRINAKTGQSPWQLRCFSVAWMRPNALVSPSGEIIN 1154
Query: 1003 -VARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
VA + S+ L + D G+ LN +V + V D ND+ P F + V +
Sbjct: 1155 WVALNREHHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTPQFMHLPASKEVNVQIW 1214
Query: 1060 TRRVLGKVDAT----DADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETE 1113
G + A D D G+N +T+ + D P FEI TG + R T
Sbjct: 1215 AEIPAGSLVANMFAKDLDAGENGTVTFSLASEDEGEPPHFEIDGETGNIRTTEHFTRNTR 1274
Query: 1114 DKYILTVVARDNG 1126
Y LTV A D G
Sbjct: 1275 PFYTLTVCASDGG 1287
Score = 51.6 bits (118), Expect = 2e-04
Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 5/134 (3%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G T ++ + R F ++ GSL + LD + + A T QA + K
Sbjct: 1452 GLTYDPKVTDSSTRFPFQMNPYTGSLTVTAPLDRETTSSF-AFTVTATDQARR-KEERKQ 1509
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-- 345
A ++ LLD+NDN P F + ++ ++E+ G + + +A D D+GENG +Y +
Sbjct: 1510 ATVAAQVFLLDVNDNRPVF-ISAVSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILT 1568
Query: 346 DDPKGAFSIDPRSG 359
+ KG F+++ +G
Sbjct: 1569 GNKKGMFTLEGNTG 1582
Score = 49.6 bits (113), Expect = 6e-04
Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
L LD + + + + S N TA A V + +LD+NDN P F D Y +
Sbjct: 1025 LAHSLDYETQSAFRFRVLASAAEPSLANT---TATAAVTVSVLDVNDNAPVFSRDLYYFT 1081
Query: 315 IVE-NLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
+ E P G V V A DKD G N + +Y L F I+ ++G
Sbjct: 1082 VSEAPSPQGL-VGTVSAADKDSGRNAQLSYILLSDGKFFRINAKTG 1126
Score = 49.2 bits (112), Expect = 9e-04
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 9/131 (6%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I VR+ VKDVNDH PVF N + E A D D + Y I+ S+
Sbjct: 102 IKVRIEVKDVNDHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDEDEDEFGTQGYRIRESE 161
Query: 1089 TDLPFEI--------SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
+ F + L+ L + LDRE +D Y LT+ A D G
Sbjct: 162 MEERFHLDHHRSGSGQHLSLDLVLMSRLDREEQDFYSLTIEAFDGG-VPPRTGTLQLRIH 220
Query: 1141 XXDVNDNSPKF 1151
D NDN P F
Sbjct: 221 VLDENDNPPVF 231
Score = 49.2 bits (112), Expect = 9e-04
Identities = 56/210 (26%), Positives = 88/210 (41%), Gaps = 20/210 (9%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G ++ + A D DSG GQ+ Y I P +S+ F ++ + G + +
Sbjct: 676 GAEVLNVIATDRDSGRFGQVTYG------IIPGDMSS-------LFDVDPQTGTLTLTSP 722
Query: 1007 LPP--ESEFRLNISALDGGNLNDNISVRVFVKDVND-HFP-VFKKTWYNFNVEEAQYTRR 1062
L + +L ++A DG + V V ++ P VF ++ Y F V E
Sbjct: 723 LTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAEDATPGT 782
Query: 1063 VLGKVDA-TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+G V+A T A G +A+++Y I D F I P +GV+S LD E + +L V
Sbjct: 783 TVGTVEAVTPAAEGFSASVSYRISSGDPQGFFSIHPRSGVISSTKPLDHELQPNVLL--V 840
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ DVNDN+P F
Sbjct: 841 IQSYSDASPVYSTTQVNIAVTDVNDNAPVF 870
Score = 49.2 bits (112), Expect = 9e-04
Identities = 67/251 (26%), Positives = 104/251 (41%), Gaps = 28/251 (11%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
E+ ++ ++F V +T+LD NDN+P FV S + S+ N T V AVD DLG
Sbjct: 2684 EFSEKHQVAFAVVFITVLDENDNSPHFVFSTV-NCSVLENLPAFTHTCSVHAVDNDLGSY 2742
Query: 493 GMVLYDLQRTSNLTITS-------PFKINPNTGTVSVAES--PILEGRHALFVEASDQPA 543
G + Y + L S F I+P TG V ++ E + VEA D+
Sbjct: 2743 GQLTYSILSPCFLDYDSGSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKGG 2802
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
T+ V +G P F Y F + + G VG + D
Sbjct: 2803 K---------TATVRVQVSIRGVDEFSPIFTQKQYHFLLPGHSKPGDVVGFVMAMD---- 2849
Query: 604 NDVSYDLLHGYE--EGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIV 659
+D D + GY P F+V + +G + V + + R R + + V L +A + +
Sbjct: 2850 HDRGVDGIVGYSLVSSSPFFSVNKTTGSVFVSEPVYR-RRGSHGEDLVKLLVSAGSPKLS 2908
Query: 660 TNATVHVVDVN 670
+ T VV +N
Sbjct: 2909 SRTTTCVVFIN 2919
Score = 48.0 bits (109), Expect = 0.002
Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 10/177 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D G + Y +I G+ LF +D G+L L L +L A + L + A
Sbjct: 684 ATDRDSGRFGQVTYGIIPGDMSSLFDVDPQTGTLTLTSPLT-----DLGAASLQLLLTAQ 738
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA-TDKDQGEN 338
+ A V + +L F Y ++ E+ G +V V A T +G +
Sbjct: 739 DGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAEDATPGTTVGTVEAVTPAAEGFS 798
Query: 339 GEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+Y++ DP+G FSI PRSG + + LD E ++ + + + V T
Sbjct: 799 ASVSYRISSGDPQGFFSIHPRSG--VISSTKPLDHELQPNVLLVIQSYSDASPVYST 853
Score = 48.0 bits (109), Expect = 0.002
Identities = 36/107 (33%), Positives = 50/107 (46%), Gaps = 11/107 (10%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF----EVDFYNISIV 316
L+ EH+ Q L+V + +P A A V I + D NDN P+F N+ I
Sbjct: 1158 LNREHHSQ---HTLKVMVTDQGHPRLNATATVHILVTDTNDNTPQFMHLPASKEVNVQIW 1214
Query: 317 ENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA---FSIDPRSG 359
+P G V + A D D GENG T+ L + +G F ID +G
Sbjct: 1215 AEIPAGSLVANMFAKDLDAGENGTVTFSLASEDEGEPPHFEIDGETG 1261
Score = 47.2 bits (107), Expect = 0.003
Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 991 YFVINERHGHVIVARSLPPESEFRLNI-----SALDGGNLNDNISVRVFVKDVNDHFPVF 1045
+F I+ R G +++ + P + E + N+ S D + V + V DVND+ PVF
Sbjct: 813 FFSIHPRSG--VISSTKPLDHELQPNVLLVIQSYSDASPVYSTTQVNIAVTDVNDNAPVF 870
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ +V + VL A DAD G N + Y ++ +D F I G +++
Sbjct: 871 LRASDAVSVSQNVLPGTVLYIAHAHDADSGSNGRVRYRLR-NDRFGTFGIDRNLGTVTLI 929
Query: 1106 GELDRETEDKYILTVVARDNG 1126
L + Y L VVA D G
Sbjct: 930 QSLLGSRQQSYHLEVVAEDGG 950
Score = 44.8 bits (101), Expect = 0.018
Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 17/164 (10%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN-NPLKTAQA 290
RY + G+ F +D+ +G +++ + LD +A A +VL V+A P A
Sbjct: 1343 RYSISEGDGSVQFGIDASSGDIYVNQPLDYEA-----AAQYVLVVRAEGAGLAPGANASV 1397
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD-DP 348
V + + D ND+ P F + + E+ G A D D N Y L DP
Sbjct: 1398 LVSVMVEDANDHTPWFPDKMVLLGLSEDATVGSLAFAFQARDADGTFPNSAVRYGLTYDP 1457
Query: 349 KGA-------FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
K F ++P +G LTV LDRE SS V A +
Sbjct: 1458 KVTDSSTRFPFQMNPYTGSLTV--TAPLDRETTSSFAFTVTATD 1499
Score = 44.4 bits (100), Expect = 0.024
Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 24/155 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--Y 1285
G P L+S+A++M+TVAD D + PVF S Y ++ E+ LV ++ +
Sbjct: 2578 GDPPLNSSAVVMLTVADRND-----NAPVFSSTEYHAQVSESSPRGTRLVQVSARDPDLG 2632
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N +R+ I++ N + + +DP +G L + +S D E Y + VRA E
Sbjct: 2633 ANSLVRFDIISGNS---KGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKH 2689
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ + V V + + D NDNSP F
Sbjct: 2690 QVAFAV--------------VFITVLDENDNSPHF 2710
Score = 42.7 bits (96), Expect = 0.075
Identities = 37/110 (33%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN--APVELVSLNLTEHY 1285
GLPSLSST V VADV D+ PVF Y + EN + PV VS +
Sbjct: 1633 GLPSLSSTQTFTVEVADVNDQ-----PPVFSQSVYNASVAENKDPGEPVARVSATDGDSE 1687
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
EN + Y +L ++ F I+P G + DRE + + + V+A
Sbjct: 1688 ENAVVWYSLLPGPGYEL---FSINPDTGLITTASYLDREQQHGFTLRVQA 1734
Score = 37.5 bits (83), Expect = 2.8
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA---- 290
++S F +S + +F ++L++DA+ L + VL ++ + + +
Sbjct: 45 VLSAPSTGFFISESRDSDVF--RDLEIDADTGLISTAVVLDRESRRQYDFVAATPTGEMI 102
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+V IE+ D+ND+ P F + N+ I E P G A D+D+ E G Y++
Sbjct: 103 KVRIEVKDVNDHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDEDEDEFGTQGYRI 157
>UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF14747, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1526
Score = 128 bits (309), Expect = 1e-27
Identities = 177/696 (25%), Positives = 294/696 (42%), Gaps = 96/696 (13%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V +LD ND P F P +Y S+K + V+ ++ D D G N + Y + +
Sbjct: 826 VKVLDVNDETPTFDP-RVYNVSLKESIPRDHVVARLACSDNDAGLNAELSYFITGGNQ-- 882
Query: 507 ITSPFKINPNTGTVS--VAESPILEGRHALFVEASDQ-PANPSERRYSLAVVTIEVTRGT 563
F + G V V + + L VEA D PA RR A V +EV +
Sbjct: 883 -DGKFSVGFRDGIVRTVVGLDRETQAAYTLIVEAIDNGPAG--SRRTGTATVFVEV-QDV 938
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFA 621
N+P F+ YE V +V GTS+ Q++ DA E V Y +L G + F+
Sbjct: 939 NDNRPI---FLQNSYETSVLESVPQGTSILQVQATDADQGENGSVLYRILTGNSNNL-FS 994
Query: 622 VEERSGVITV---VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
++ ++G++T D + M + EA E + S V ++V D NDE V +
Sbjct: 995 IDRQTGLVTRGLRALDRETSSSHMLEVEAYNSDEGSMRSSV-RVIIYVNDANDEVPVFTQ 1053
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
++ + ++E +AG I G+G G V + + + D ++ ++ G +
Sbjct: 1054 QQYNRL--GLRE-TAGVGTSVIVVRATDPDTGDG-GAVAYALVSGSDRKFEVDVST-GLV 1108
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LD E + +T++ E ++ V F A YE + E
Sbjct: 1109 TTVDYLDYETKTTVYVTLLNELDEAV---------------------AFSSAGYEASLRE 1147
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYT--LFGEGKEMFDVDENTGVVKFIGDSLDRE 856
N GTE+ ++A AD + + +F +D TG + G LDRE
Sbjct: 1148 NIATGTEVIQ---VQAQSADNLNQLTYRFDPDTSPAALALFKIDSVTGRITVTG-LLDRE 1203
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
+ Y L++ + D+ K + I +S ++
Sbjct: 1204 RGDAYTLTV-----------------VADDGGPKKDSTVITSDS---------ISQQVSI 1237
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
TI++ + N D+ + I EN P+G + + A D D+GLNG I +
Sbjct: 1238 TILD-ENDNSPVFDITSDTSVD-ITENTPMGEKVAVVLARDKDAGLNGLINFTL------ 1289
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVR 1032
++ + +V + +N +G V V L ES + L + A D G+ + + S+
Sbjct: 1290 ----VAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRYLLKVRATDNGSPPRHTDHSLT 1345
Query: 1033 VFVKDVNDHFPVFK-KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
+ + DVND+ PV + + YN ++ E + +V ATD D G NA L Y+I + DL
Sbjct: 1346 INILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYITAGNQDL 1405
Query: 1092 PFEISPLTG-VLSVNGELDRETEDKYILTVVARDNG 1126
F + +TG +++ DRE + +YILTV D+G
Sbjct: 1406 TFRMDRMTGEMVTRPAPPDRERQQEYILTVTVEDDG 1441
Score = 125 bits (302), Expect = 8e-27
Identities = 236/956 (24%), Positives = 375/956 (39%), Gaps = 104/956 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK-VKAVDPDLGQNGMVLYDLQRTSNL 505
+ L+D NDN P F S Y + A+VG + ++A D D G N M L ++
Sbjct: 212 ILLIDKNDNAPKFNSSE-YRLQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTGNNSE 270
Query: 506 TIT-SPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
T SP + P L+ H S A V IE+
Sbjct: 271 YFTLSPTAVQGRADIRMRVAMP-LDYEHIRSYSFSLYANESMSDHVGFARVFIELINEND 329
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAV 622
P F Y + N GTS+ +I DA + ++ ++ Y P F++
Sbjct: 330 NR----PIFSKPLYNISLPENTAPGTSLLRILATDA---DAGTFGIVRYYFSDDPDQFSL 382
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+E +G + + L + +A ++ V+V+DVND + K A+
Sbjct: 383 DEETGWVILQASLDYELMRRFTLTVLA-RDGGGEETTGRIRVNVLDVNDNAPLFQKEAY- 440
Query: 683 PIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ ++EN A + ++ T+ S N + I + I
Sbjct: 441 --VGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYFSIIMVEGYAVISVT 498
Query: 742 KPLDREK--RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+PLD E+ + + V+ + + G + VT+ + DENDNPP F ++Y I EN
Sbjct: 499 RPLDYEQVPSGMIHLEVMVK-DGGSPALNSTVPVTVEVIDENDNPPEFSKSSYIVKIPEN 557
Query: 800 SKIGTEIKMDNIIKATDAD---EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
G E ++ ATD D E A +Y+L EG F ++ +G + LDRE
Sbjct: 558 INAG-EWATVLLVNATDLDASREFGQASLIYSL--EGSSQFRLNSRSGEITTTA-LLDRE 613
Query: 857 KKIMYKLSLVARDTGGLSSE-----AELIIMIGDENDNKPEFNQ------IEENSKVRIH 905
K Y L + A D GG+ + A + I I D NDN P + + E S +
Sbjct: 614 LKSEYILIVRAVD-GGVGPQQKTGIATVNITILDINDNAPVWRDEPYHANVVEMSPINTD 672
Query: 906 RETKL-----NGTAGFTIIEVKPKNKFALDVDQLGPLFLI----------PENIPIGTTI 950
+ L NG G + + P+N F G + P + + TI
Sbjct: 673 VISVLALDPDNGENGTVVYSISPENPFYTINSSTGKIRTSGVTLDRESSNPRDAILMRTI 732
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA-DALEVKRYFVINERHG-----HVIVA 1004
I ++A+D S Q+R ++ V++ L+ D + FV G V A
Sbjct: 733 I-ISAVDRGSP---QLRASASTTVFVNLLDLNDNDPKFLNLPFVAEVPEGLAIGSSVFKA 788
Query: 1005 RSLPPESE-------FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
S PP+S + L I A D GN ++ V V DVND P F YN +++
Sbjct: 789 FSPPPQSWTAEQIGLYYLRIIAYDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVYNVSLK 848
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ V+ ++ +D D G NA L+YFI + D F + G++ LDRET+
Sbjct: 849 ESIPRDHVVARLACSDNDAGLNAELSYFITGGNQDGKFSVGFRDGIVRTVVGLDRETQAA 908
Query: 1116 YILTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y L V A DNG DVNDN P F L+ + + S
Sbjct: 909 YTLIVEAIDNGPAGSRRTGTATVFVEVQDVNDNRPIF------LQNSYETSVLESVPQGT 962
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI---LYSLPQRKNQQ------ 1225
S++ + A EN + + +N+ I GL+ L +L + +
Sbjct: 963 SILQVQATDADQGENGSVLYRILTGNSNNLFSIDRQTGLVTRGLRALDRETSSSHMLEVE 1022
Query: 1226 --NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY-ELEIEENVNAPVELVSLNLT 1282
N S+ S+ +++ V D DEV PVF + Y L + E ++ + T
Sbjct: 1023 AYNSDEGSMRSSVRVIIYVNDANDEV-----PVFTQQQYNRLGLRETAGVGTSVIVVRAT 1077
Query: 1283 --EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ + + Y +++ +D R F +D G + V D E K T V + E
Sbjct: 1078 DPDTGDGGAVAYALVSGSD----RKFEVDVSTGLVTTVDYLDYETKTTVYVTLLNE 1129
Score = 107 bits (257), Expect = 2e-21
Identities = 138/472 (29%), Positives = 205/472 (43%), Gaps = 71/472 (15%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN P+F+ N YE S+ + GT I +V+A D D G+NG VLY + T N
Sbjct: 931 VFVEVQDVNDNRPIFL-QNSYETSVLESVPQGTSILQVQATDADQGENGSVLYRI-LTGN 988
Query: 505 LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ F I+ TG V+ + H L VEA + ++ R S+ V+
Sbjct: 989 --SNNLFSIDRQTGLVTRGLRALDRETSSSHMLEVEAYN--SDEGSMRSSVRVIIY---- 1040
Query: 562 GTKGNKPDIPDFMGAPY-EFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGV 618
++P F Y + G+GTSV +R D + V+Y L+ G +
Sbjct: 1041 -VNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYALVSGSDR-- 1097
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND-ERGVLL 677
F V+ +G++T VD L D+E T TV+V +N+ + V
Sbjct: 1098 KFEVDVSTGLVTTVDYL--------DYE-------------TKTTVYVTLLNELDEAVAF 1136
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA---- 733
A ++EN A T + + N+ L T A+A
Sbjct: 1137 SSAGYEA--SLRENIATG-------TEVIQVQAQSADNLNQLTYRFDPDTSPAALALFKI 1187
Query: 734 --EDGTIFTQKPLDREKRDVYRMTVIAE-----FNKGVISGAGI-YQVTIYIEDENDNPP 785
G I LDRE+ D Y +TV+A+ + VI+ I QV+I I DENDN P
Sbjct: 1188 DSVTGRITVTGLLDRERGDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSP 1247
Query: 786 VFEHATYEGF-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD--E 841
VF+ + I EN+ +G ++ ++ A D D G N L +TL G K++F +
Sbjct: 1248 VFDITSDTSVDITENTPMGEKVA---VVLARDKDAGLNGLINFTLVAGNMKDVFKIKTVN 1304
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
+T ++ LDRE Y L + A D G ++ L I I D NDN P
Sbjct: 1305 HTYGEVYVNAPLDRESVDRYLLKVRATDNGSPPRHTDHSLTINILDVNDNAP 1356
Score = 100 bits (240), Expect = 3e-19
Identities = 127/458 (27%), Positives = 194/458 (42%), Gaps = 58/458 (12%)
Query: 472 NAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR 531
N VG + V A DPD G G VL+ Q S F I+ GTV+V + E
Sbjct: 4 NTPVGRSVFMVNATDPDQGTGGSVLFSFQPPSPF-----FAIDGARGTVTVTKPLDYETT 58
Query: 532 HA--LFVEASDQPA-NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
A L V A+DQ P R +LA+ +V + P F PY + +V +
Sbjct: 59 SAYQLTVNATDQDKLRPLSRLANLAISITDV-------QDMDPIFTNLPYSTNIEEDVPL 111
Query: 589 ----GTSVG---------QIRVNDAFEQN-----DVSYDLLHGYEEGVPFAVEERSGVIT 630
T +G ++R A +Q+ + Y ++ G V FA++ SG +T
Sbjct: 112 ISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGNTNSV-FALDYISGSLT 170
Query: 631 VVDDLSRYNRPMYD------FEAVALQEN---ANLSIVTNATVHVVDVNDERGVLLKGAH 681
V L R N P+Y +A L+E+ ++ +++T T+ ++D ND +
Sbjct: 171 VSGQLDREN-PLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEY 229
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT---- 737
I + + G A+ N V FL N + A G
Sbjct: 230 RLQITELAQ--VGFALPLFIQAEDKDEGVNSMFQV-FLTGNNSEYFTLSPTAVQGRADIR 286
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ PLD E Y ++ A N+ + G +V I + +ENDN P+F Y +
Sbjct: 287 MRVAMPLDYEHIRSYSFSLYA--NESMSDHVGFARVFIELINENDNRPIFSKPLYNISLP 344
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN+ GT + I ATDAD GT + Y F + + F +DE TG V + SLD E
Sbjct: 345 ENTAPGTSLLR---ILATDADAGTFGIVRY-YFSDDPDQFSLDEETGWV-ILQASLDYEL 399
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ L+++ARD GG + + + + D NDN P F +
Sbjct: 400 MRRFTLTVLARDGGGEETTGRIRVNVLDVNDNAPLFQK 437
Score = 94.3 bits (224), Expect = 2e-17
Identities = 117/474 (24%), Positives = 189/474 (39%), Gaps = 42/474 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ F V + L++ NDN P+F LY S+ N GT + ++ A D D G G+V Y
Sbjct: 315 VGFARVFIELINENDNRPIF-SKPLYNISLPENTAPGTSLLRILATDADAGTFGIVRYYF 373
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTI 557
+ F ++ TG V + S E R L V A D + R + V+ +
Sbjct: 374 SDDPD-----QFSLDEETGWVILQASLDYELMRRFTLTVLARDGGGEETTGRIRVNVLDV 428
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL--HG 613
+ P F Y + N V ++R D+ N ++Y ++
Sbjct: 429 ---------NDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASA 479
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRP--MYDFEAVALQENA-NLSIVTNATVHVVDVN 670
+ + E VI+V L P M E + + L+ TV V+D N
Sbjct: 480 FPSYFSIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVIDEN 539
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D K ++ I + EN + N + + + LI + + +
Sbjct: 540 DNPPEFSKSSY---IVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEGSSQFR 596
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ G I T LDRE + Y + V A + G GI V I I D NDN PV+
Sbjct: 597 LNSRSGEITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNITILDINDNAPVWRD 656
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
Y ++E S I T++ + A D D G N +Y++ E + ++ +TG ++
Sbjct: 657 EPYHANVVEMSPINTDVIS---VLALDPDNGENGTVVYSISPE-NPFYTINSSTGKIRTS 712
Query: 850 GDSLDREKK------IMYKLSLVARDTGG----LSSEAELIIMIGDENDNKPEF 893
G +LDRE +M + + A D G S+ + + + D NDN P+F
Sbjct: 713 GVTLDRESSNPRDAILMRTIIISAVDRGSPQLRASASTTVFVNLLDLNDNDPKF 766
Score = 93.9 bits (223), Expect = 3e-17
Identities = 80/256 (31%), Positives = 118/256 (46%), Gaps = 13/256 (5%)
Query: 134 VPRGLTIFKDI-RAFDRDKPNTPNSDV--HYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
VP GL I + +AF + + +Y + D G+F S+ L KVLD
Sbjct: 775 VPEGLAIGSSVFKAFSPPPQSWTAEQIGLYYLRIIAYDAGNFPRTSTST---LTVKVLDV 831
Query: 191 DAGDKEFQ-LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
+ F V S K + D D G+ A L Y + GN FS+
Sbjct: 832 NDETPTFDPRVYNVSLKESIPRDHVVARLACSDNDAGLNAELSYFITGGNQDGKFSVGFR 891
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G + LD + + A T +++ + +T A V +E+ D+NDN P F +
Sbjct: 892 DGIVRTVVGLDRETQ---AAYTLIVEAIDNGPAGSRRTGTATVFVEVQDVNDNRPIFLQN 948
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQT 367
Y S++E++P G S+LQV ATD DQGENG Y++ + FSID ++G L R
Sbjct: 949 SYETSVLESVPQGTSILQVQATDADQGENGSVLYRILTGNSNNLFSIDRQTG-LVTRGLR 1007
Query: 368 VLDREAHSSLRMKVYA 383
LDRE SS ++V A
Sbjct: 1008 ALDRETSSSHMLEVEA 1023
Score = 83.4 bits (197), Expect = 4e-14
Identities = 58/172 (33%), Positives = 90/172 (52%), Gaps = 11/172 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLD--SVNG--SLFLEKELDLDAEHNLQANTFV 273
I A D+D GV + + ++GN+ + F+L +V G + + + LD EH +++ +F
Sbjct: 247 IQAEDKDEGVNSMFQV-FLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEH-IRSYSFS 304
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L S ++ ARV IEL++ NDN P F YNIS+ EN G S+L+++ATD
Sbjct: 305 LYANESMSDH---VGFARVFIELINENDNRPIFSKPLYNISLPENTAPGTSLLRILATDA 361
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G G Y D FS+D +GW+ + Q LD E + V A++
Sbjct: 362 DAGTFGIVRYYFSDDPDQFSLDEETGWVIL--QASLDYELMRRFTLTVLARD 411
Score = 82.6 bits (195), Expect = 8e-14
Identities = 62/185 (33%), Positives = 94/185 (50%), Gaps = 12/185 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+DQDLG + Y ++SGN +F+LD ++GSL + + LD E+ L + F L V+
Sbjct: 134 ITAMDQDLGRPRGIGYTIVSGNTNSVFALDYISGSLTVSGQ--LDRENPLYSAGFTLTVK 191
Query: 278 ASQLNNPLKTAQARV----EIELLDLNDNLPEFEVDFYNISIVENLPNGFSV-LQVMATD 332
A++L + A V I L+D NDN P+F Y + I E GF++ L + A D
Sbjct: 192 ATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITELAQVGFALPLFIQAED 251
Query: 333 KDQGENGEF-TYQLDDPKGAFSIDPRS--GWLTVRNQTV--LDREAHSSLRMKVYAKETN 387
KD+G N F + + F++ P + G +R + LD E S +YA E+
Sbjct: 252 KDEGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSYSFSLYANESM 311
Query: 388 PSVVG 392
VG
Sbjct: 312 SDHVG 316
Score = 79.8 bits (188), Expect = 5e-13
Identities = 119/485 (24%), Positives = 192/485 (39%), Gaps = 61/485 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN GT+++++ A D D+G G +RY F+ + P + S D E G
Sbjct: 343 LPENTAPGTSLLRILATDADAGTFGIVRYYFSDD----PDQFSLD-----------EETG 387
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VI+ SL E F L + A DGG +RV V DVND+ P+F+K Y ++ E
Sbjct: 388 WVILQASLDYELMRRFTLTVLARDGGGEETTGRIRVNVLDVNDNAPLFQKEAYVGSLREN 447
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTG--VLSVNGELDRETED 1114
+ + + ++ ATD D N LTY I S F I + G V+SV LD E
Sbjct: 448 EQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYFSIIMVEGYAVISVTRPLDYEQVP 507
Query: 1115 KYI--LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ L V+ +D G D NDN P+F ++ K PE ++
Sbjct: 508 SGMIHLEVMVKDGG-SPALNSTVPVTVEVIDENDNPPEFSKSSYIV--KIPE--NINAGE 562
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL------------YSLPQ 1220
+ +V+++ + + + + + + +G I Y L
Sbjct: 563 WATVLLVNATDLDASREFGQASLIYSLEGSSQFRLNSRSGEITTTALLDRELKSEYILIV 622
Query: 1221 RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
R +G + A + +T+ D+ D + PV+ Y + E +++S+
Sbjct: 623 RAVDGGVGPQQKTGIATVNITILDIND-----NAPVWRDEPYHANVVEMSPINTDVISV- 676
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
L +N EN T + + I P N Y + S +++ + + R
Sbjct: 677 LALDPDN--------GENGTVV---YSISPEN-PFYTINSSTGKIRTSGVTLDRESSNPR 724
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVK--VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
L I A D + V V + D+NDN PKF N P V +P G
Sbjct: 725 DAILMRTIIISAVDRGSPQLRASASTTVFVNLLDLNDNDPKFL--NLPFVAEVPEGLAIG 782
Query: 1399 YQVMQ 1403
V +
Sbjct: 783 SSVFK 787
Score = 79.0 bits (186), Expect = 9e-13
Identities = 48/151 (31%), Positives = 83/151 (54%), Gaps = 11/151 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTFVLQV 276
A D+D G+ + + L++GN + +F + +VN G +++ LD ++ + ++L+V
Sbjct: 1274 ARDKDAGLNGLINFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRES-----VDRYLLKV 1328
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF-YNISIVENLPNGFSVLQVMATDKDQ 335
+A+ +P + + I +LD+NDN P E YN+SI EN+ G SVL+VMATD+D
Sbjct: 1329 RATDNGSPPRHTDHSLTINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMATDRDI 1388
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVR 364
G N Y + + F +D +G + R
Sbjct: 1389 GPNAMLFYYITAGNQDLTFRMDRMTGEMVTR 1419
Score = 72.1 bits (169), Expect = 1e-10
Identities = 108/442 (24%), Positives = 191/442 (43%), Gaps = 44/442 (9%)
Query: 476 GTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA-----ESPILEG 530
G + K+ A+D DLG+ + Y + S T S F ++ +G+++V+ E+P+
Sbjct: 128 GYEVRKITAMDQDLGRPRGIGYTI--VSGNT-NSVFALDYISGSLTVSGQLDRENPLYSA 184
Query: 531 RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGT 590
L V+A++ +R S A V T + P F + Y + +G
Sbjct: 185 GFTLTVKATELK---EDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITELAQVGF 241
Query: 591 SVGQ-IRVNDAFEQ-NDVSYDLLHG----YEEGVPFAVEERSGV-ITVVDDLSRYNRPMY 643
++ I+ D E N + L G Y P AV+ R+ + + V L + Y
Sbjct: 242 ALPLFIQAEDKDEGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSY 301
Query: 644 DFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFH 702
F A + ++ + +++ ND R + K ++ + EN+A G ++ +I
Sbjct: 302 SFSLYANESMSDHVGFARVFIELINENDNRPIFSKPLYN---ISLPENTAPGTSLLRILA 358
Query: 703 TNMSSIYGNGT-GNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEF 760
T+ + GT G VR+ + D D ++ E+ G + Q LD E + +TV+A
Sbjct: 359 TDADA----GTFGIVRYYFS---DDPDQFSLDEETGWVILQASLDYELMRRFTLTVLARD 411
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
G + ++ + + D NDN P+F+ Y G + EN + + ++ATD D
Sbjct: 412 GGGEETTG---RIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVAR---LRATDEDSP 465
Query: 821 TNALFMYTLFGEGK--EMFDVDENTG-VVKFIGDSLDREK--KIMYKLSLVARDTGG--L 873
N YT+ F + G V + LD E+ M L ++ +D G L
Sbjct: 466 PNNFLTYTIISASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPAL 525
Query: 874 SSEAELIIMIGDENDNKPEFNQ 895
+S + + + DENDN PEF++
Sbjct: 526 NSTVPVTVEVIDENDNPPEFSK 547
Score = 72.1 bits (169), Expect = 1e-10
Identities = 112/463 (24%), Positives = 183/463 (39%), Gaps = 70/463 (15%)
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E+ +Y + +IA ++ G +T+ + D ND P F+ Y N + I
Sbjct: 799 EQIGLYYLRIIA-YDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVY------NVSLKESI 851
Query: 807 KMDNIIK---ATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYK 862
D+++ +D D G NA Y + G ++ F V G+V+ + LDRE + Y
Sbjct: 852 PRDHVVARLACSDNDAGLNAELSYFITGGNQDGKFSVGFRDGIVRTVV-GLDRETQAAYT 910
Query: 863 LSLVARDTGGLSSE----AELIIMIGDENDNKPEF--NQIEENSKVRIHRETKL------ 910
L + A D G S A + + + D NDN+P F N E + + + T +
Sbjct: 911 LIVEAIDNGPAGSRRTGTATVFVEVQDVNDNRPIFLQNSYETSVLESVPQGTSILQVQAT 970
Query: 911 ------NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
NG+ + I+ N F++D Q G + + T+ + ++ + G
Sbjct: 971 DADQGENGSVLYRILTGNSNNLFSID-RQTGLVTRGLRALDRETSSSHMLEVEAYNSDEG 1029
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRY--FVINERHG---HVIVARSLPPES-------- 1011
+R +Y+ + ++Y + E G VIV R+ P++
Sbjct: 1030 SMRSSVRVIIYVNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAY 1089
Query: 1012 --------EFRLNISA-----LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+F +++S +D + +V V + + D F Y ++ E
Sbjct: 1090 ALVSGSDRKFEVDVSTGLVTTVDYLDYETKTTVYVTLLNELDEAVAFSSAGYEASLRENI 1149
Query: 1059 YTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLP---FEISPLTGVLSVNGELDRETED 1114
T + +V A AD N N LTY P + F+I +TG ++V G LDRE D
Sbjct: 1150 ATGTEVIQVQAQSAD---NLNQLTYRFDPDTSPAALALFKIDSVTGRITVTGLLDRERGD 1206
Query: 1115 KYILTVVARDNG------XXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y LTVVA D G D NDNSP F
Sbjct: 1207 AYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSPVF 1249
Score = 71.7 bits (168), Expect = 1e-10
Identities = 111/454 (24%), Positives = 181/454 (39%), Gaps = 64/454 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+IP + +L D D+GLN ++ Y +I F + R G
Sbjct: 847 LKESIPRDHVVARLACSDNDAGLNAELSY------FITGGNQDGK-------FSVGFRDG 893
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDN----ISVRVFVKDVNDHFPVFKKTWYNFN 1053
V L E++ + L + A+D G +V V V+DVND+ P+F + Y +
Sbjct: 894 IVRTVVGLDRETQAAYTLIVEAIDNGPAGSRRTGTATVFVEVQDVNDNRPIFLQNSYETS 953
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN-GELDRET 1112
V E+ + +V ATDAD G+N ++ Y I +++ F I TG+++ LDRET
Sbjct: 954 VLESVPQGTSILQVQATDADQGENGSVLYRILTGNSNNLFSIDRQTGLVTRGLRALDRET 1013
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
++L V A ++ VND A DE+ + + + L
Sbjct: 1014 SSSHMLEVEAYNSDEGSMRSSVRVIIY----VND------ANDEVPVFTQQQYNRLG--- 1060
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL---PQRKNQQNLGL 1229
+ E A +GT+V V A D D G+G G + Y+L RK + ++
Sbjct: 1061 -------------LRETAGVGTSVIVVRATDPD-TGDG-GAVAYALVSGSDRKFEVDVST 1105
Query: 1230 PSLSSTAIL---MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
+++ L T V E+ + F S YE + EN+ E++ +
Sbjct: 1106 GLVTTVDYLDYETKTTVYVTLLNELDEAVAFSSAGYEASLRENIATGTEVIQVQAQSADN 1165
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
++ Y + F ID G + + DRE D Y + V A+
Sbjct: 1166 LNQLTYRFDPDTSPAALALFKIDSVTGRITVTGLLDRERGDAYTLTVVADDGG------- 1218
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
P + + +V + I D NDNSP F
Sbjct: 1219 ---PKKDSTVITSDSISQQVSITILDENDNSPVF 1249
Score = 70.5 bits (165), Expect = 3e-10
Identities = 67/247 (27%), Positives = 109/247 (44%), Gaps = 42/247 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I +N P+G ++ +NA D D G G + + F PPS +F I+ G
Sbjct: 1 ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQ-----PPSP----------FFAIDGARG 45
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
V V + L E S ++L ++A D L+ ++ + + DV D P+F Y+ N+
Sbjct: 46 TVTVTKPLDYETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTNI 105
Query: 1055 EE----AQYTRRVLG------------KVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
EE T+ LG K+ A D D G+ + Y I +T+ F + +
Sbjct: 106 EEDVPLISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGNTNSVFALDYI 165
Query: 1099 TGVLSVNGELDRET---EDKYILTVVA---RDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
+G L+V+G+LDRE + LTV A +++ D NDN+PKF
Sbjct: 166 SGSLTVSGQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFN 225
Query: 1153 AFDELLE 1159
+ + L+
Sbjct: 226 SSEYRLQ 232
Score = 65.3 bits (152), Expect = 1e-08
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 6/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G ++ Y +++GN LFS+D G L LD E +++ +L+V+
Sbjct: 967 VQATDADQGENGSVLYRILTGNSNNLFSIDRQTG-LVTRGLRALDRE---TSSSHMLEVE 1022
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQG 336
A + + RV I + D ND +P F YN + + E G SV+ V ATD D G
Sbjct: 1023 AYNSDEGSMRSSVRVIIYVNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTG 1082
Query: 337 ENGEFTYQL-DDPKGAFSIDPRSGWLT 362
+ G Y L F +D +G +T
Sbjct: 1083 DGGAVAYALVSGSDRKFEVDVSTGLVT 1109
Score = 64.1 bits (149), Expect = 3e-08
Identities = 83/316 (26%), Positives = 138/316 (43%), Gaps = 41/316 (12%)
Query: 83 VTVYIEDVNDNVPIFLDTPY-----------------HVTVDELTPTGEKAFIFLIAPIG 125
+ V + DVNDN P+F Y T ++ P + + A
Sbjct: 421 IRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAF 480
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
PS + + G + R D ++ P+ +H ++ D G AL S+ PV +
Sbjct: 481 PSY-FSIIMVEGYAVISVTRPLDYEQ--VPSGMIHLEVMV-KDGGSPALNST-VPVTV-- 533
Query: 186 KVLDYDAGDKEFQL--VIMASGKRIHK-EILFPEPIHAIDQDLG--VG-ATLRYELISGN 239
+V+D + EF I+ + I+ E ++A D D G A+L Y L G+
Sbjct: 534 EVIDENDNPPEFSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSL-EGS 592
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ--LNNPLKTAQARVEIELL 297
+ F L+S +G + LD + + + ++L V+A + KT A V I +L
Sbjct: 593 SQ--FRLNSRSGEITTTALLDRELK-----SEYILIVRAVDGGVGPQQKTGIATVNITIL 645
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
D+NDN P + + Y+ ++VE P V+ V+A D D GENG Y + ++I+
Sbjct: 646 DINDNAPVWRDEPYHANVVEMSPINTDVISVLALDPDNGENGTVVYSISPENPFYTINSS 705
Query: 358 SGWLTVRNQTVLDREA 373
+G + T LDRE+
Sbjct: 706 TGKIRTSGVT-LDRES 720
Score = 61.3 bits (142), Expect = 2e-07
Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 10/185 (5%)
Query: 417 TTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG 476
T V D G K ++ + + V +T+LD NDN+PVF ++ + N +G
Sbjct: 1209 TLTVVADDGGPKKDSTVITSDSISQ--QVSITILDENDNSPVFDITSDTSVDITENTPMG 1266
Query: 477 TVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHAL 534
+ V A D D G NG++ + L + + +N G V V E R+ L
Sbjct: 1267 EKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRYLL 1326
Query: 535 FVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ 594
V A+D + P +SL + ++V N P I G Y + NVG GTSV +
Sbjct: 1327 KVRATDNGSPPRHTDHSLTINILDV----NDNAPVIESQKG--YNVSISENVGGGTSVLR 1380
Query: 595 IRVND 599
+ D
Sbjct: 1381 VMATD 1385
Score = 54.0 bits (124), Expect = 3e-05
Identities = 81/341 (23%), Positives = 135/341 (39%), Gaps = 57/341 (16%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK---------------AFIFLIAPIGP 126
+V V ++DVNDN PIFL Y +V E P G + ++ I
Sbjct: 930 TVFVEVQDVNDNRPIFLQNSYETSVLESVPQGTSILQVQATDADQGENGSVLYRILTGNS 989
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
+ + GL + + +RA DR+ ++ +V +D+G ++ SS + ++ +
Sbjct: 990 NNLFSIDRQTGL-VTRGLRALDRETSSSHMLEVE---AYNSDEG--SMRSSVRVIIYVND 1043
Query: 187 VLDYDA--GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
D +++ + + + ++ + A D D G G + Y L+SG+DRK F
Sbjct: 1044 ANDEVPVFTQQQYNRLGLRETAGVGTSVIV---VRATDPDTGDGGAVAYALVSGSDRK-F 1099
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+D G + LD + KT V + LL+ D
Sbjct: 1100 EVDVSTGLVTTVDYLDYET----------------------KTT---VYVTLLNELDEAV 1134
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA---FSIDPRSGWL 361
F Y S+ EN+ G V+QV A D + + D A F ID +G +
Sbjct: 1135 AFSSAGYEASLRENIATGTEVIQVQAQSADNLNQLTYRFDPDTSPAALALFKIDSVTGRI 1194
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAK 402
TV +LDRE + + V A + P T S I++
Sbjct: 1195 TVTG--LLDRERGDAYTLTVVADDGGPKKDSTVITSDSISQ 1233
Score = 53.2 bits (122), Expect = 5e-05
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 8/150 (5%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA---RVEIELLDL 299
LF +DSV G + + LD + + T V + ++ + T+ + +V I +LD
Sbjct: 1184 LFKIDSVTGRITVTGLLDRE-RGDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDE 1242
Query: 300 NDNLPEFEVDF-YNISIVENLPNGFSVLQVMATDKDQGENG--EFTYQLDDPKGAFSIDP 356
NDN P F++ ++ I EN P G V V+A DKD G NG FT + K F I
Sbjct: 1243 NDNSPVFDITSDTSVDITENTPMGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIKT 1302
Query: 357 -RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ V LDRE+ +KV A +
Sbjct: 1303 VNHTYGEVYVNAPLDRESVDRYLLKVRATD 1332
Score = 52.4 bits (120), Expect = 9e-05
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 14/173 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G +RY D+ FSLD G + L+ LD + F L V
Sbjct: 356 ILATDADAGTFGIVRYYFSDDPDQ--FSLDEETGWVILQASLDYELMRR-----FTLTVL 408
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A T + RV + LD+NDN P F+ + Y S+ EN V ++ ATD+D
Sbjct: 409 ARDGGGEETTGRIRVNV--LDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPP 466
Query: 338 NGEFTYQLDDPK---GAFSIDPRSGWLTVRNQTVLDREAHSS--LRMKVYAKE 385
N TY + FSI G+ + LD E S + ++V K+
Sbjct: 467 NNFLTYTIISASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKD 519
Score = 50.8 bits (116), Expect = 3e-04
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ S V V + + DAND PVF ++ A VGT + V+A DPD G G V Y
Sbjct: 1031 MRSSVRVIIYVNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYA 1090
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFV 536
L S+ F+++ +TG V+ + E + ++V
Sbjct: 1091 LVSGSD----RKFEVDVSTGLVTTVDYLDYETKTTVYV 1124
Score = 47.2 bits (107), Expect = 0.003
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+Q V +T+LD NDN PV+ Y ++ + + T + V A+DPD G+NG V+
Sbjct: 632 QQKTGIATVNITILDINDNAPVW-RDEPYHANVVEMSPINTDVISVLALDPDNGENGTVV 690
Query: 497 YDLQRTSNL-TI-TSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSL 552
Y + + TI +S KI + T+ S + + + A D+ +P R +
Sbjct: 691 YSISPENPFYTINSSTGKIRTSGVTLDRESSNPRDAILMRTIIISAVDR-GSPQLRASAS 749
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
V + + N D P F+ P+ V + IG+SV
Sbjct: 750 TTVFVNL---LDLNDND-PKFLNLPFVAEVPEGLAIGSSV 785
Score = 46.8 bits (106), Expect = 0.005
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + +LD NDN PV Y S+ N GT + +V A D D+G N M+ Y +
Sbjct: 1343 SLTINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYI-TAG 1401
Query: 504 NLTITSPFKINPNTGTVSVAESP 526
N +T F+++ TG + +P
Sbjct: 1402 NQDLT--FRMDRMTGEMVTRPAP 1422
Score = 46.0 bits (104), Expect = 0.008
Identities = 27/71 (38%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
I++N P G SV V ATD DQG G + P F+ID G +TV LD E
Sbjct: 1 ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQPPSPFFAIDGARGTVTVTKP--LDYETT 58
Query: 375 SSLRMKVYAKE 385
S+ ++ V A +
Sbjct: 59 SAYQLTVNATD 69
Score = 43.2 bits (97), Expect = 0.056
Identities = 50/185 (27%), Positives = 81/185 (43%), Gaps = 24/185 (12%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
GT+ KPLD E Y++TV A + + + + I I D D P+F + Y
Sbjct: 45 GTVTVTKPLDYETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTN 104
Query: 796 IMENSKI--GTEIKMDNI-----------IKATDADEGTNALFMYTLF-GEGKEMFDVDE 841
I E+ + T+ + + I A D D G YT+ G +F +D
Sbjct: 105 IEEDVPLISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGNTNSVFALDY 164
Query: 842 NTGVVKFIGDSLDREKKIM---YKLSLVARD--TGGLSSEAELI----IMIGDENDNKPE 892
+G + G LDRE + + L++ A + S+A ++ I++ D+NDN P+
Sbjct: 165 ISGSLTVSG-QLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPK 223
Query: 893 FNQIE 897
FN E
Sbjct: 224 FNSSE 228
Score = 42.7 bits (96), Expect = 0.075
Identities = 17/41 (41%), Positives = 25/41 (60%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
G G Q + +V + I D+NDN P++ D PYH V E++P
Sbjct: 628 GVGPQQKTGIATVNITILDINDNAPVWRDEPYHANVVEMSP 668
Score = 38.3 bits (85), Expect = 1.6
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 11/102 (10%)
Query: 74 LNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT 133
L +S ++ + I DV D PIF + PY ++E P LI+ L T
Sbjct: 73 LRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVP--------LISQTQTHLGPLHT 124
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE 175
+G + K I A D+D P + Y+IVSGN + FAL+
Sbjct: 125 ALQGYEVRK-ITAMDQDL-GRPRG-IGYTIVSGNTNSVFALD 163
>UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2;
Euteleostomi|Rep: Protocadherin-9 precursor. - Takifugu
rubripes
Length = 1011
Score = 126 bits (305), Expect = 4e-27
Identities = 128/463 (27%), Positives = 203/463 (43%), Gaps = 28/463 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL--- 499
+ +++ + D NDN P+F PS + S+ N + + A DPD G N + Y+L
Sbjct: 127 IKIKIIVKDTNDNAPMF-PSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELING 185
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
Q L I + + V ++ E + ++ + S ++ S A++ + V
Sbjct: 186 QSAFGLDIVETPE-GEKWPQLIVQQNLDREQKDTYVMKIKVEDGG-SPQKSSTAILQVTV 243
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T N+ P F E + N IGTSV Q++ DA + + G +
Sbjct: 244 T-DVNDNR---PVFKEGQIEVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPA 299
Query: 620 ----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE-RG 674
FA+ SG+ITV L R ++ +A +++ + T T++V DVND
Sbjct: 300 TKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARAT-VTINVTDVNDNPPN 358
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ L+ SPI V + +I +S + G V I ++DV +
Sbjct: 359 IDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFI--EKDVPFHLKAVY 416
Query: 735 DG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
D + T LD E Y ++A + G S V + +EDENDN P+F
Sbjct: 417 DNQYLLETSALLDYEGTKEYNFKIVAS-DSGKPSLNQTALVRVRLEDENDNAPIFTQPVI 475
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
E +MEN+K + I ATD D G NA +Y L G FD+D TGV+
Sbjct: 476 ELAVMENNKRDLFL---TTISATDEDSGKNAEIVYQL-GPNASFFDLDRKTGVLT-ASRV 530
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
DRE + + ++ ARD G L ++A +I+ + DENDN P+F
Sbjct: 531 FDREDQDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKF 573
Score = 121 bits (292), Expect = 1e-25
Identities = 145/544 (26%), Positives = 236/544 (43%), Gaps = 50/544 (9%)
Query: 402 KWRRQPLETNAPLE-KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV 460
KW + ++ N E K TYV KV + Q S ++VT+ D NDN PVF
Sbjct: 201 KWPQLIVQQNLDREQKDTYVMKIKVE------DGGSPQKSSTAILQVTVTDVNDNRPVFK 254
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV 520
+ E + N+ +GT + +++A D D+G N + Y + F +N +G +
Sbjct: 255 EGQI-EVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRLFALNSTSGLI 313
Query: 521 SVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP-DFMGAP 577
+V E H L V ASD ++P+ A VTI VT N P+I ++ +P
Sbjct: 314 TVQRPLDREETAIHKLSVLASDGSSSPAR-----ATVTINVT-DVNDNPPNIDLRYIISP 367
Query: 578 YE--FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF---AVEERSGVITVV 632
++ I T + I V+D + D++ ++ E+ VPF AV + ++
Sbjct: 368 INGTVFLSEKDPINTKIALITVSD--KDTDINGKVICFIEKDVPFHLKAVYDNQYLLETS 425
Query: 633 DDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPII-FHVKE 690
L Y+F+ VA +L+ V + D ND + + P+I V E
Sbjct: 426 ALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNAPIFTQ----PVIELAVME 481
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
N+ +F T +S+ + N + + + + G + + DRE +D
Sbjct: 482 NNKR----DLFLTTISATDEDSGKNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQD 537
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN 810
+ TV A N G V + + DENDN P F H ++ F+ EN + +
Sbjct: 538 RFLFTVTARDN-GTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTV---G 593
Query: 811 IIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
+I TD+D G NA ++ + E F +D +GV+K S DRE++ Y + A D+
Sbjct: 594 VITVTDSDAGENAAVSLSILND-NENFILDPFSGVIK-SNVSFDREQQSSYTFDVRAVDS 651
Query: 871 G--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFA 928
G SS A++ I + D NDN P N+ ++ L+ G + EV FA
Sbjct: 652 GRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKL---VPLSSIPGSVVAEV-----FA 703
Query: 929 LDVD 932
+D D
Sbjct: 704 VDGD 707
Score = 95.1 bits (226), Expect = 1e-17
Identities = 131/496 (26%), Positives = 206/496 (41%), Gaps = 72/496 (14%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V V DVND R V +G I H+ ENSA G ++ Q+ T+ + I N + ++
Sbjct: 241 VTVTDVNDNRPVFKEGQ---IEVHIPENSAIGTSVVQLQATD-ADIGANA--EIHYVFGT 294
Query: 723 QQDVTDDIAIA---EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
Q A G I Q+PLDRE+ +++++V+A + G S A VTI + D
Sbjct: 295 QVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLA--SDGSSSPARA-TVTINVTD 351
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
NDNPP + +I+ ++ + ++ D + + T+ + D
Sbjct: 352 VNDNPPNIDLR----YIIS--------PINGTVFLSEKDPINTKIALITVSDK-----DT 394
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFNQIE 897
D N V+ FI + K +Y + + L E E I + KP NQ
Sbjct: 395 DINGKVICFIEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQ-- 452
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALD 957
+ VR+ E + + FT +P + A+ + LFL TTI +A D
Sbjct: 453 -TALVRVRLEDENDNAPIFT----QPVIELAVMENNKRDLFL--------TTI---SATD 496
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRL 1015
DSG N +I Y+ +F ++ + G + +R E + F
Sbjct: 497 EDSGKNAEIVYQLGPNA---------------SFFDLDRKTGVLTASRVFDREDQDRFLF 541
Query: 1016 NISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
++A D G L +V V V D ND+ P F + F V E +G + TD+D
Sbjct: 542 TVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSD 601
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
G+NA ++ I + + F + P +GV+ N DRE + Y V A D+G
Sbjct: 602 AGENAAVSLSILNDNEN--FILDPFSGVIKSNVSFDREQQSSYTFDVRAVDSG-RPPCSS 658
Query: 1134 XXXXXXXXXDVNDNSP 1149
DVNDN+P
Sbjct: 659 AAKVTINVIDVNDNTP 674
Score = 93.1 bits (221), Expect = 5e-17
Identities = 111/421 (26%), Positives = 181/421 (42%), Gaps = 59/421 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN IGT++++L A D D G N +I Y F ++V P+ KR F +N G
Sbjct: 262 IPENSAIGTSVVQLQATDADIGANAEIHYVFGTQV--SPA--------TKRLFALNSTSG 311
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW----YNFN 1053
+ V R L E +L++ A DG + +V + V DVND+ P + N
Sbjct: 312 LITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPNIDLRYIISPINGT 371
Query: 1054 V--EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGEL 1108
V E + + +D D N + FI + D+PF + + +L + L
Sbjct: 372 VFLSEKDPINTKIALITVSDKDTDINGKVICFI---EKDVPFHLKAVYDNQYLLETSALL 428
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-YAFDELLEWKHPE--- 1164
D E +Y +VA D+G D NDN+P F EL ++ +
Sbjct: 429 DYEGTKEYNFKIVASDSG-KPSLNQTALVRVRLEDENDNAPIFTQPVIELAVMENNKRDL 487
Query: 1165 -------ADELSNHNFESVMMIPVYKATIEENAPIGT-TVAKVFANDTDFIGNGNGLILY 1216
DE S N E V + + + + G T ++VF + L+
Sbjct: 488 FLTTISATDEDSGKNAEIVYQLGPNASFFDLDRKTGVLTASRVFDRE------DQDRFLF 541
Query: 1217 SLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPV 1274
++ R N G P L + A ++VTV D E + P F +++ + EN+ + V
Sbjct: 542 TVTARDN----GTPPLQTQATVIVTVLD-----ENDNNPKFTHNHFQFFVSENLPKYSTV 592
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
++++ ++ EN + ILN+N+ F++DP +G + S DRE + +Y VR
Sbjct: 593 GVITVTDSDAGENAAVSLSILNDNE-----NFILDPFSGVIKSNVSFDREQQSSYTFDVR 647
Query: 1335 A 1335
A
Sbjct: 648 A 648
Score = 82.2 bits (194), Expect = 1e-13
Identities = 117/468 (25%), Positives = 192/468 (41%), Gaps = 65/468 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN I + +A D D+G N +YE + S D +E E+
Sbjct: 152 IPENTLINSRFAIPSATDPDTGPNSVHKYELING----QSAFGLDIVETPE----GEKWP 203
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+IV ++L E + + + I DGG+ + + ++V V DVND+ PVFK+ ++
Sbjct: 204 QLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKEGQIEVHIP 263
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYF----IQPSDTDLPFEISPLTGVLSVNGELDRE 1111
E + ++ ATDAD G NA + Y + P+ L F ++ +G+++V LDRE
Sbjct: 264 ENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRL-FALNSTSGLITVQRPLDRE 322
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKH-PEADE 1167
+ L+V+A D DVNDN P Y + E D
Sbjct: 323 ETAIHKLSVLASDG---SSSPARATVTINVTDVNDNPPNIDLRYIISPINGTVFLSEKDP 379
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAK------VFANDTDFIGNGNGLILYSLPQR 1221
++ + +I V + N + + K D ++ + L+ Y +
Sbjct: 380 INT----KIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYLLETSALLDYEGTKE 435
Query: 1222 KN----QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
N + G PSL+ TA++ V + D E + P+F EL + EN + L
Sbjct: 436 YNFKIVASDSGKPSLNQTALVRVRLED-----ENDNAPIFTQPVIELAVMENNKRDLFLT 490
Query: 1278 SLNLTEHYENFKMR-YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+++ T+ Y L N + F +D + G L R DRE +D + V A
Sbjct: 491 TISATDEDSGKNAEIVYQLGPNAS----FFDLDRKTGVLTASRVFDREDQDRFLFTVTA- 545
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
R + L + V+V + D NDN+PKFT+ +
Sbjct: 546 RDNGTPPL----------------QTQATVIVTVLDENDNNPKFTHNH 577
Score = 78.6 bits (185), Expect = 1e-12
Identities = 59/178 (33%), Positives = 91/178 (51%), Gaps = 13/178 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL---QANTFVLQV 276
A D D G + +YELI+G + F LD V EK L + NL Q +T+V+++
Sbjct: 167 ATDPDTGPNSVHKYELING--QSAFGLDIVETPEG-EKWPQLIVQQNLDREQKDTYVMKI 223
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ +P K++ A +++ + D+NDN P F+ + I EN G SV+Q+ ATD D G
Sbjct: 224 KVEDGGSPQKSSTAILQVTVTDVNDNRPVFKEGQIEVHIPENSAIGTSVVQLQATDADIG 283
Query: 337 ENGEFTYQLDD-----PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
N E Y K F+++ SG +TV Q LDRE + ++ V A + + S
Sbjct: 284 ANAEIHYVFGTQVSPATKRLFALNSTSGLITV--QRPLDREETAIHKLSVLASDGSSS 339
Score = 78.6 bits (185), Expect = 1e-12
Identities = 58/189 (30%), Positives = 87/189 (46%), Gaps = 13/189 (6%)
Query: 198 QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEK 257
+L +M + KR LF I A D+D G A + Y+L G + F LD G L +
Sbjct: 476 ELAVMENNKRD----LFLTTISATDEDSGKNAEIVYQL--GPNASFFDLDRKTGVLTASR 529
Query: 258 ELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE 317
D + + + F+ V A P QA V + +LD NDN P+F + + + E
Sbjct: 530 VFDREDQ-----DRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSE 584
Query: 318 NLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSL 377
NLP +V + TD D GEN + + + F +DP SG +++ DRE SS
Sbjct: 585 NLPKYSTVGVITVTDSDAGENAAVSLSILNDNENFILDPFSG--VIKSNVSFDREQQSSY 642
Query: 378 RMKVYAKET 386
V A ++
Sbjct: 643 TFDVRAVDS 651
Score = 63.3 bits (147), Expect = 5e-08
Identities = 46/153 (30%), Positives = 66/153 (43%), Gaps = 6/153 (3%)
Query: 244 FSLDSV-NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F L +V + LE LD E + N ++ AS P A V + L D NDN
Sbjct: 410 FHLKAVYDNQYLLETSALLDYEGTKEYN---FKIVASDSGKPSLNQTALVRVRLEDENDN 466
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P F ++++EN + + ATD+D G+N E YQL F +D ++G LT
Sbjct: 467 APIFTQPVIELAVMENNKRDLFLTTISATDEDSGKNAEIVYQLGPNASFFDLDRKTGVLT 526
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
V DRE V A++ + T A
Sbjct: 527 A--SRVFDREDQDRFLFTVTARDNGTPPLQTQA 557
Score = 61.3 bits (142), Expect = 2e-07
Identities = 77/320 (24%), Positives = 135/320 (42%), Gaps = 38/320 (11%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE----------LTPTGEKA 116
+V +G ++ V V +ED NDN PIF + V E ++ T E +
Sbjct: 440 IVASDSGKPSLNQTALVRVRLEDENDNAPIFTQPVIELAVMENNKRDLFLTTISATDEDS 499
Query: 117 F--IFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
++ +GP+ + + R + R FDR+ + D V+ D+G L
Sbjct: 500 GKNAEIVYQLGPNASF-FDLDRKTGVLTASRVFDRE-----DQDRFLFTVTARDNGTPPL 553
Query: 175 ESSHKPVLLLRKVLDYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
++ ++ + D + FQ + + + + I D D G A +
Sbjct: 554 QTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGV----ITVTDSDAGENAAVS 609
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
++ ND + F LD +G ++ + D E Q +++ V+A P ++ A+V
Sbjct: 610 LSIL--NDNENFILDPFSG--VIKSNVSFDRE---QQSSYTFDVRAVDSGRPPCSSAAKV 662
Query: 293 EIELLDLNDNLPEFEVDFYNISI----VENLPNGFSVLQVMATDKDQGENGEFTYQL--D 346
I ++D+NDN P N S + ++P G V +V A D D G N E Y +
Sbjct: 663 TINVIDVNDNTPIVIYPPSNTSFKLVPLSSIP-GSVVAEVFAVDGDTGMNAELKYTIVSG 721
Query: 347 DPKGAFSIDPRSGWLTVRNQ 366
+ KG F IDP +G +T+ +
Sbjct: 722 NNKGLFRIDPVTGNITLEEK 741
Score = 60.9 bits (141), Expect = 3e-07
Identities = 88/364 (24%), Positives = 138/364 (37%), Gaps = 30/364 (8%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I +++ VKD ND+ P+F N ++ E ATD D G N+ Y +
Sbjct: 127 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQ 186
Query: 1089 TDLPFEI-----SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
+ +I L V LDRE +D Y++ + D G D
Sbjct: 187 SAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGG-SPQKSSTAILQVTVTD 245
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI----GTTVAKV 1199
VNDN P F + +E PE + SV+ + A I NA I GT V+
Sbjct: 246 VNDNRPVFK--EGQIEVHIPENSAIGT----SVVQLQATDADIGANAEIHYVFGTQVSPA 299
Query: 1200 FANDTDFIGNGNGLILYSLPQRKNQQNL-GLPSLSSTAILMVTVADVPDEV-EMSDKPVF 1257
+ + +GLI P + + + L L+S A V V +++D P
Sbjct: 300 -TKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPN 358
Query: 1258 ISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYL 1317
I Y I +N V L + N K+ +++ DTDI + +
Sbjct: 359 IDLRY---IISPINGTVFLSEKDPI----NTKIALITVSDKDTDINGKVICFIEKDVPFH 411
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
+++ V D ++ + Y + VA D + V VR++D NDN+
Sbjct: 412 LKA----VYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNA 467
Query: 1378 PKFT 1381
P FT
Sbjct: 468 PIFT 471
Score = 59.3 bits (137), Expect = 8e-07
Identities = 45/151 (29%), Positives = 74/151 (49%), Gaps = 10/151 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFV--PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
S V + ++D NDN P+ + PSN + ++ G+V+ +V AVD D G N + Y
Sbjct: 658 SAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDGDTGMNAELKYT 717
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
+ +N + F+I+P TG +++ E P + G H L V SD + ++L +V
Sbjct: 718 IVSGNNKGL---FRIDPVTGNITLEEKPAVTDIGLHRLVVNISD--LGYPKSLHTLVLVF 772
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVG 587
+ V T GN I D + E + N+G
Sbjct: 773 LYV-NDTVGNSTLIYDLIRRTMETPIDRNIG 802
Score = 49.6 bits (113), Expect = 6e-04
Identities = 50/171 (29%), Positives = 71/171 (41%), Gaps = 13/171 (7%)
Query: 226 GVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-----LQVQAS 279
GV A L Y L+S D L + S G +F +D E +F +++
Sbjct: 59 GVSANLVYRLVSKAGDNPLVRVLSSTGEIFTTSNR-IDREKLCPGPSFEDSECSFEIEVV 117
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
L N +++I + D NDN P F NISI EN ATD D G N
Sbjct: 118 ILPNDYFRL-IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS 176
Query: 340 EFTYQLDDPKGAFSID----PR-SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y+L + + AF +D P W + Q LDRE + MK+ ++
Sbjct: 177 VHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVED 227
Score = 42.7 bits (96), Expect = 0.075
Identities = 43/174 (24%), Positives = 75/174 (43%), Gaps = 22/174 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN+P +T+ + D D+G N + S L F+++
Sbjct: 580 FFVSENLPKYSTVGVITVTDSDAGENAAV---------------SLSILNDNENFILDPF 624
Query: 998 HGHVI--VARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPV--FKKTWYN 1051
G + V+ +S + ++ A+D G + V + V DVND+ P+ + + +
Sbjct: 625 SGVIKSNVSFDREQQSSYTFDVRAVDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTS 684
Query: 1052 FN-VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
F V + V+ +V A D D G NA L Y I + F I P+TG +++
Sbjct: 685 FKLVPLSSIPGSVVAEVFAVDGDTGMNAELKYTIVSGNNKGLFRIDPVTGNITL 738
>UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14979, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 2982
Score = 126 bits (304), Expect = 5e-27
Identities = 129/473 (27%), Positives = 201/473 (42%), Gaps = 42/473 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V +LD NDN P+FV S ++ ++ N +G I ++AVD D G N + Y R ++
Sbjct: 469 VTVQVLDVNDNAPIFV-STPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEY---RLTS 524
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
T PF IN +TG + VA E + VEA DQ S+++ ++V
Sbjct: 525 TTPNFPFAINNSTGWIVVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDN 584
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
P+F Y + + +GTSV + D + V+Y + G F++
Sbjct: 585 N-------PEFTQKAYYMRLNEDAAVGTSVLTVSAVDQDINSVVTYQISSGNTRN-RFSI 636
Query: 623 EERS--GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+S G+IT+ L Y A + L V+V D N R V + +
Sbjct: 637 TSQSGGGLITLALPLDYKLERQYVLTITA--SDGTLFDTAKVFVNVTDANTHRPV-FQSS 693
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIAEDGTIF 739
H + + ++ G + I T+ TG N R + + G +
Sbjct: 694 HYTVNIN-EDRPMGTTVVLISATD------EDTGENARITYFMDDSIPQFDIDPDSGAVT 746
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
TQ LD E + Y + + A N G+ + + I + D NDN P F Y G +ME+
Sbjct: 747 TQMELDYEDQVSYTLAITARDN-GIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMED 805
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVKFIGDSLDREK 857
+ T + + ATD D G N YT G +G F ++ +G+V+ + LDRE
Sbjct: 806 VPVFTSVVQ---VSATDRDSGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTL-RRLDREN 861
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ------IEENSKV 902
+Y L A D G L + + + I D NDN P F + +EENS +
Sbjct: 862 VPVYNLQAFAVDKGVPALKTPVNIHVTILDVNDNPPVFEKDELDIMVEENSPI 914
Score = 125 bits (301), Expect = 1e-26
Identities = 129/462 (27%), Positives = 210/462 (45%), Gaps = 39/462 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ S ++ +T+LD NDNNP F Y + +A VGT + V AVD D+ N +V Y
Sbjct: 568 MSSSASISMTVLDVNDNNPEFT-QKAYYMRLNEDAAVGTSVLTVSAVDQDI--NSVVTYQ 624
Query: 499 LQRTSNLTITSPFKINPNTG----TVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
+ S+ + F I +G T+++ LE ++ L + ASD + A
Sbjct: 625 I---SSGNTRNRFSITSQSGGGLITLALPLDYKLERQYVLTITASDGTL------FDTAK 675
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
V + VT P F + Y + + +GT+V I D E + + +
Sbjct: 676 VFVNVTDANTHR----PVFQSSHYTVNINEDRPMGTTVVLISATD--EDTGENARITYFM 729
Query: 615 EEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVND 671
++ +P F ++ SG +T +L ++ Y A+ ++N S T + V DVND
Sbjct: 730 DDSIPQFDIDPDSGAVTTQMELDYEDQVSYTL-AITARDNGIPQKSDTTYLEILVNDVND 788
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
L+ + + +++ ++ Q+ T+ S G V + +D D
Sbjct: 789 NGPRFLRDHYVGSV--MEDVPVFTSVVQVSATDRDS---GLNGRVFYTFQGGEDGDGDFI 843
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I + G + T + LDRE VY + A +KGV + + + I D NDNPPVFE
Sbjct: 844 IESTSGIVRTLRRLDRENVPVYNLQAFA-VDKGVPALKTPVNIHVTILDVNDNPPVFEKD 902
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
+ + ENS IG + + ATD DEG+NA MY + G E+F +D +G + +
Sbjct: 903 ELDIMVEENSPIGLVV---GHVSATDPDEGSNAQIMYQIVEGNIPEVFQLDIFSGELTSL 959
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
D LD E + Y + +V + L S A + I + D+NDN P
Sbjct: 960 ID-LDYETRNEYVI-VVQATSAPLVSRATVHIKLVDKNDNVP 999
Score = 112 bits (270), Expect = 6e-23
Identities = 117/444 (26%), Positives = 195/444 (43%), Gaps = 57/444 (12%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+ + T+++V N + Q + E+ +GT+++ ++A+D D +N + Y+
Sbjct: 571 SASISMTVLDVNDNNP---EFTQKAYYMRLNEDAAVGTSVLTVSAVDQD--INSVVTYQI 625
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP----ESEFRLNISALDGGNLN 1026
+S + F I + G ++ +LP E ++ L I+A DG L
Sbjct: 626 SSG-------------NTRNRFSITSQSGGGLITLALPLDYKLERQYVLTITASDG-TLF 671
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
D V V V D N H PVF+ + Y N+ E + + + ATD D G+NA +TYF+
Sbjct: 672 DTAKVFVNVTDANTHRPVFQSSHYTVNINEDRPMGTTVVLISATDEDTGENARITYFM-- 729
Query: 1087 SDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
D +P F+I P +G ++ ELD E + Y L + ARDNG DVN
Sbjct: 730 -DDSIPQFDIDPDSGAVTTQMELDYEDQVSYTLAITARDNG-IPQKSDTTYLEILVNDVN 787
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DN P+F D + + F SV+ + N + T D D
Sbjct: 788 DNGPRFLR-DHYVGSVMEDVPV-----FTSVVQVSATDRDSGLNGRVFYTFQGGEDGDGD 841
Query: 1206 FIGNGNGLILYSLPQRKNQQNL------------GLPSLSSTAILMVTVADVPDEVEMSD 1253
FI I+ +L +R +++N+ G+P+L + + VT+ DV D +
Sbjct: 842 FIIESTSGIVRTL-RRLDRENVPVYNLQAFAVDKGVPALKTPVNIHVTILDVND-----N 895
Query: 1254 KPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPR 1311
PVF ++ +EEN + V VS + N ++ Y I+ N I F +D
Sbjct: 896 PPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVEGN---IPEVFQLDIF 952
Query: 1312 NGTLYLVRSPDREVKDTYEVIVRA 1335
+G L + D E ++ Y ++V+A
Sbjct: 953 SGELTSLIDLDYETRNEYVIVVQA 976
Score = 110 bits (265), Expect = 2e-22
Identities = 116/424 (27%), Positives = 182/424 (42%), Gaps = 26/424 (6%)
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEAS 539
+KAVD D G+ G + Y ++ + S F ++P G VS E E + H V A
Sbjct: 183 LKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETKDTHVFRVTAV 242
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
D A RR ++A +TI V+ N P F Y+ + N+ IG V +R D
Sbjct: 243 DHGA---PRRTAMATLTITVSDTNDHN----PVFEQQDYKENIRENLEIGYEVLTVRATD 295
Query: 600 --AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS 657
A ++ Y +++G F ++ RSGVI + R Y A + +
Sbjct: 296 GDAPVNGNILYRIINGNGSNDVFEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPG 355
Query: 658 IVT-NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+ ATVH+V V D+ + + + V E+ A +I + V
Sbjct: 356 PRSATATVHIV-VEDDNDNAPQFSEKRYVVQVPEDMAPNT--EILQVTATDEDRGSNAVV 412
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN-KGVISG-AGIYQVT 774
F I + A+ G + LD E Y + + A+ + +S +G+ VT
Sbjct: 413 HFSIMSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNISGL--VT 470
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDN P+F ++ ++EN +G I I+A DAD G N+ Y L
Sbjct: 471 VQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIH---IQAVDADSGDNSRLEYRLTSTTP 527
Query: 835 EM-FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
F ++ +TG + + LDRE Y + ARD G +SS A + + + D NDN P
Sbjct: 528 NFPFAINNSTGWI-VVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDNNP 586
Query: 892 EFNQ 895
EF Q
Sbjct: 587 EFTQ 590
Score = 102 bits (245), Expect = 7e-20
Identities = 95/317 (29%), Positives = 146/317 (46%), Gaps = 32/317 (10%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPL----TVPR 136
VTV + DVNDN PIF+ TP+ TV E P G + A G + + T P
Sbjct: 469 VTVQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPN 528
Query: 137 GLTIFKD-----IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+ + A + D+ + D + V D G+ + SS + VLD +
Sbjct: 529 FPFAINNSTGWIVVAAELDRESV---DFYNFGVEARDQGYPVMSSSAS---ISMTVLDVN 582
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLFSLDS 248
+ EF A R++++ + A+DQD + + + Y++ SGN R FS+ S
Sbjct: 583 DNNPEFTQ--KAYYMRLNEDAAVGTSVLTVSAVDQD--INSVVTYQISSGNTRNRFSITS 638
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
+G + L LD + Q +VL + AS TA +V + + D N + P F+
Sbjct: 639 QSGGGLITLALPLDYKLERQ---YVLTITASD-GTLFDTA--KVFVNVTDANTHRPVFQS 692
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
Y ++I E+ P G +V+ + ATD+D GEN TY +DD F IDP SG V Q
Sbjct: 693 SHYTVNINEDRPMGTTVVLISATDEDTGENARITYFMDDSIPQFDIDPDSG--AVTTQME 750
Query: 369 LDREAHSSLRMKVYAKE 385
LD E S + + A++
Sbjct: 751 LDYEDQVSYTLAITARD 767
Score = 98.7 bits (235), Expect = 1e-18
Identities = 105/464 (22%), Positives = 200/464 (43%), Gaps = 35/464 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ + +T+ D ND+NPVF + Y+ +++ N ++G + V+A D D NG +LY +
Sbjct: 251 AMATLTITVSDTNDHNPVFEQQD-YKENIRENLEIGYEVLTVRATDGDAPVNGNILYRII 309
Query: 501 RTSNLTITSPFKINPNTGTV---SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ F+I+ +G + + + +E + L VEA+DQ +P R A T+
Sbjct: 310 NGNG--SNDVFEIDSRSGVIRTRGLVDREQVEA-YMLLVEANDQGRDPGPRS---ATATV 363
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYE 615
+ + + + P F Y V ++ T + Q+ D ++ V + ++ G
Sbjct: 364 HIV--VEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDRGSNAVVHFSIMSGNT 421
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTN-ATVHVVDVNDE 672
G F ++ ++G + +V L Y + Q+ LS ++ TV V+DVND
Sbjct: 422 RG-QFYIDAQTGKMDLVSHLDYEANKEYTLR-IRAQDGGRPPLSNISGLVTVQVLDVNDN 479
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + +P V EN +G I H + + + +
Sbjct: 480 APIFVS---TPFQATVLEN---VPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPNFPFAI 533
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I LDRE D Y V A ++G + +++ + D NDN P F
Sbjct: 534 NNSTGWIVVAAELDRESVDFYNFGVEAR-DQGYPVMSSSASISMTVLDVNDNNPEFTQKA 592
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDV-DENTGVVKFI 849
Y + E++ +GT +++ + D+ N++ Y + G + F + ++ G + +
Sbjct: 593 YYMRLNEDAAVGT-----SVLTVSAVDQDINSVVTYQISSGNTRNRFSITSQSGGGLITL 647
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
LD + + Y L++ A D G L A++ + + D N ++P F
Sbjct: 648 ALPLDYKLERQYVLTITASD-GTLFDTAKVFVNVTDANTHRPVF 690
Score = 96.3 bits (229), Expect = 6e-18
Identities = 84/338 (24%), Positives = 150/338 (44%), Gaps = 25/338 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSL 128
G + +A ++T+ + D ND+ P+F Y + E G + AP+ ++
Sbjct: 245 GAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGDAPVNGNI 304
Query: 129 TIPLTVPRGLT-IFK-DIRAF---DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+ G +F+ D R+ R + + + +V ND G S +
Sbjct: 305 LYRIINGNGSNDVFEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPGPRSATATVH 364
Query: 184 LRKVLDYDAGDK--EFQLVIMASGKRI-HKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ D D + E + V+ + EIL + A D+D G A + + ++SGN
Sbjct: 365 IVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEIL---QVTATDEDRGSNAVVHFSIMSGNT 421
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIELLDL 299
R F +D+ G + L LD +A + L+++A P L V +++LD+
Sbjct: 422 RGQFYIDAQTGKMDLVSHLDYEANKE-----YTLRIRAQDGGRPPLSNISGLVTVQVLDV 476
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPR 357
NDN P F + +++EN+P G+S++ + A D D G+N Y+L P F+I+
Sbjct: 477 NDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPNFPFAINNS 536
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
+GW+ V + LDRE+ V A++ V+ + A
Sbjct: 537 TGWIVVAAE--LDRESVDFYNFGVEARDQGYPVMSSSA 572
Score = 85.0 bits (201), Expect = 1e-14
Identities = 97/407 (23%), Positives = 160/407 (39%), Gaps = 30/407 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+ IG ++ + A D D+ +NG I Y I S D E+ + G
Sbjct: 278 IRENLEIGYEVLTVRATDGDAPVNGNILYR------IINGNGSNDVFEIDSRSGVIRTRG 331
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
V + N D G + +V + V+D ND+ P F + Y V E
Sbjct: 332 LVDREQVEAYMLLVEANDQGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMA 391
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
+ +V ATD D G NA + + I +T F I TG + + LD E +Y L
Sbjct: 392 PNTEILQVTATDEDRGSNAVVHFSIMSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLR 451
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF-ESVMM 1178
+ A+D G DVNDN+P F + +A L N S++
Sbjct: 452 IRAQDGGRPPLSNISGLVTVQVLDVNDNAPIFVSTPF-------QATVLENVPLGYSIIH 504
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ----------QNLG 1228
I A +N+ + + N I N G I+ + + ++ G
Sbjct: 505 IQAVDADSGDNSRLEYRLTSTTPNFPFAINNSTGWIVVAAELDRESVDFYNFGVEARDQG 564
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF 1288
P +SS+A + +TV DV D + P F + Y + + E+ +++++ + N
Sbjct: 565 YPVMSSSASISMTVLDVND-----NNPEFTQKAYYMRLNEDAAVGTSVLTVSAVDQDINS 619
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ Y I + N T R + G + L D +++ Y + + A
Sbjct: 620 VVTYQISSGN-TRNRFSITSQSGGGLITLALPLDYKLERQYVLTITA 665
Score = 83.0 bits (196), Expect = 6e-14
Identities = 58/174 (33%), Positives = 86/174 (49%), Gaps = 13/174 (7%)
Query: 218 IHAIDQDLGVGATLRY---ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A+D D G L Y L LF++D NG++ + LD + + +T V
Sbjct: 183 LKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETK-----DTHVF 237
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+V A P +TA A + I + D ND+ P FE Y +I ENL G+ VL V ATD D
Sbjct: 238 RVTAVDHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGD 297
Query: 335 QGENGEFTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y++ + G+ F ID RSG +R + ++DRE + + V A +
Sbjct: 298 APVNGNILYRIINGNGSNDVFEIDSRSG--VIRTRGLVDREQVEAYMLLVEAND 349
Score = 82.6 bits (195), Expect = 8e-14
Identities = 106/448 (23%), Positives = 176/448 (39%), Gaps = 48/448 (10%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G + L A+D D G G++ Y F ++ S F ++ +G V
Sbjct: 177 GRPSLVLKAVDADEGEAGRLEY-FIEALFDSRSN---------SLFAVDPANGAVSTVEV 226
Query: 1007 LPPESEFR--LNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E++ ++A+D G ++ + V D NDH PVF++ Y N+ E
Sbjct: 227 LDRETKDTHVFRVTAVDHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGY 286
Query: 1063 VLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ V ATD D N N+ Y I + ++ FEI +GV+ G +DRE + Y+L V
Sbjct: 287 EVLTVRATDGDAPVNGNILYRIINGNGSNDVFEIDSRSGVIRTRGLVDREQVEAYMLLVE 346
Query: 1122 ARDNGXX-XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIP 1180
A D G D NDN+P+F +++ A +
Sbjct: 347 ANDQGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDR 406
Query: 1181 VYKATIEENAPIGTTVAKVF----ANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS-T 1235
A + + G T + + D + + + R Q+ G P LS+ +
Sbjct: 407 GSNAVVHFSIMSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNIS 466
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL--TEHYENFKMRYY 1293
++ V V DV D + P+F+S ++ + ENV ++ + + +N ++ Y
Sbjct: 467 GLVTVQVLDVND-----NAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYR 521
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
+ T F I+ G + + DRE D Y V A Q YPV
Sbjct: 522 L---TSTTPNFPFAINNSTGWIVVAAELDRESVDFYNFGVEARDQG---------YPVMS 569
Query: 1354 DVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ + + DVNDN+P+FT
Sbjct: 570 S--------SASISMTVLDVNDNNPEFT 589
Score = 79.4 bits (187), Expect = 7e-13
Identities = 92/361 (25%), Positives = 154/361 (42%), Gaps = 31/361 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L V V + DAN + PVF S+ Y ++ + +GT + + A D D G+N +
Sbjct: 667 DGTLFDTAKVFVNVTDANTHRPVFQSSH-YTVNINEDRPMGTTVVLISATDEDTGENARI 725
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y + + F I+P++G V+ E + + L + A D L
Sbjct: 726 TYFMDDS-----IPQFDIDPDSGAVTTQMELDYEDQVSYTLAITARDNGIPQKSDTTYLE 780
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
++ +V + P F+ Y V +V + TSV Q+ D V Y
Sbjct: 781 ILVNDV-------NDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRVFYTFQ 833
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVN 670
G + F +E SG++ + L R N P+Y+ +A A+ + L N V ++DVN
Sbjct: 834 GGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVPALKTPVNIHVTILDVN 893
Query: 671 DERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD- 728
D V K + V+ENS G +G + T+ N + + N +V
Sbjct: 894 DNPPVFEK---DELDIMVEENSPIGLVVGHVSATDPDE-GSNAQIMYQIVEGNIPEVFQL 949
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
DI G + + LD E R+ Y + V+ + ++S A ++ I + D+NDN PV +
Sbjct: 950 DIF---SGELTSLIDLDYETRNEY-VIVVQATSAPLVSRATVH---IKLVDKNDNVPVLK 1002
Query: 789 H 789
+
Sbjct: 1003 N 1003
Score = 72.1 bits (169), Expect = 1e-10
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 12/169 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+D G A + Y + + F +D +G++ + ELD + + + + L +
Sbjct: 712 ISATDEDTGENARITYFMDDSIPQ--FDIDPDSGAVTTQMELDYEDQVS-----YTLAIT 764
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K+ +EI + D+NDN P F D Y S++E++P SV+QV ATD+D G
Sbjct: 765 ARDNGIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGL 824
Query: 338 NGE--FTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG +T+Q +D G F I+ SG VR LDRE ++ +A
Sbjct: 825 NGRVFYTFQGGEDGDGDFIIESTSG--IVRTLRRLDRENVPVYNLQAFA 871
Score = 67.3 bits (157), Expect = 3e-09
Identities = 81/331 (24%), Positives = 133/331 (40%), Gaps = 21/331 (6%)
Query: 44 VDSDSPQNVVKFRLGCDFD-EGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
+ S S ++ L D+ E ++ I A + V V + D N + P+F + Y
Sbjct: 636 ITSQSGGGLITLALPLDYKLERQYVLTITASDGTLFDTAKVFVNVTDANTHRPVFQSSHY 695
Query: 103 HVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTIFK---DIRAFDRDKPNTPNS 157
V ++E P G + G + I + + F D A
Sbjct: 696 TVNINEDRPMGTTVVLISATDEDTGENARITYFMDDSIPQFDIDPDSGAVTTQMELDYED 755
Query: 158 DVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE 216
V Y++ ++ D+G + +L+ V D G + + + S
Sbjct: 756 QVSYTLAITARDNGIPQKSDTTYLEILVNDV--NDNGPRFLRDHYVGSVMEDVPVFTSVV 813
Query: 217 PIHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLD--AEHNLQANTFV 273
+ A D+D G+ + Y G D F ++S +G + + LD + +NLQA F
Sbjct: 814 QVSATDRDSGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQA--FA 871
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ L P+ + + +LD+NDN P FE D +I + EN P G V V ATD
Sbjct: 872 VDKGVPALKTPVN-----IHVTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDP 926
Query: 334 DQGENGEFTYQLDDPK--GAFSIDPRSGWLT 362
D+G N + YQ+ + F +D SG LT
Sbjct: 927 DEGSNAQIMYQIVEGNIPEVFQLDIFSGELT 957
Score = 61.7 bits (143), Expect = 2e-07
Identities = 82/329 (24%), Positives = 147/329 (44%), Gaps = 37/329 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFL----------DTPYHVTVDELTPT----GEKAFI 118
G+ Q S + + + DVNDN P FL D P +V +++ T G +
Sbjct: 769 GIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRV 828
Query: 119 FLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
F G + I + +R DR+ N P ++ V D G AL++
Sbjct: 829 FYTFQGGEDGDGDFIIESTSGIVRTLRRLDRE--NVPVYNLQAFAV---DKGVPALKT-- 881
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELIS 237
PV + +LD + F+ + + I L + A D D G A + Y+++
Sbjct: 882 -PVNIHVTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVE 940
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN ++F LD +G L +DLD E N +V+ VQA+ + PL ++A V I+L+
Sbjct: 941 GNIPEVFQLDIFSGE--LTSLIDLDYE---TRNEYVIVVQAT--SAPL-VSRATVHIKLV 992
Query: 298 DLNDNLP---EFEVDF--YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF 352
D NDN+P F++ F Y + + P+G + ++ A D D + +++++ +
Sbjct: 993 DKNDNVPVLKNFQIIFNNYVTNKYSSFPSGV-IGRIPAHDPDVSDQLHYSFEVGNELNLV 1051
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
++ +G + + +R +S+R+ V
Sbjct: 1052 LLNQSTGEIQLSQALDNNRPLEASMRISV 1080
Score = 47.2 bits (107), Expect = 0.003
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Query: 811 IIKATDADEGTNA---LFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
++KA DADEG F+ LF +F VD G V + + LDRE K + +
Sbjct: 182 VLKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTV-EVLDRETKDTHVFRVT 240
Query: 867 ARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
A D G ++ A L I + D ND+ P F Q + +R + E
Sbjct: 241 AVDHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLE 283
>UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C
CG31009-PA, partial; n=3; Endopterygota|Rep: PREDICTED:
similar to Cad99C CG31009-PA, partial - Apis mellifera
Length = 1556
Score = 125 bits (302), Expect = 8e-27
Identities = 120/458 (26%), Positives = 200/458 (43%), Gaps = 35/458 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+SFV V L D NDN P+ +P + ++++ + V+ KV+A D D G+N + Y +
Sbjct: 459 LSFV---VILNDVNDNAPM-LPM-IPPITVQAG-ETKKVVTKVEATDNDEGENAEITYSI 512
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
SN + FKI+P TG + + ++ V+A+D+ +YS +V + V
Sbjct: 513 YHVSNNGLHK-FKIDPRTGVIESVRKLNAGEQFSITVQATDKGG-----KYSQTIVEVNV 566
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
G P F YE V I +++ + D E + VSY ++ G +
Sbjct: 567 IPGPNTRSPV---FQQPVYEVQVSEGASINSTMTIVHAVDP-ENDPVSYSIVSGNDLR-Q 621
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
FA+ ++SGVITV+ L R + Y + +++ L + V D+ND+ +
Sbjct: 622 FAIGDKSGVITVIRKLDREDLTRYQL-LIKAEDSGGLFSTATVNIKVTDINDKNPEFVG- 679
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
P F VKE A IG++ H + N + + + T D E G +
Sbjct: 680 --LPYEFSVKEGEARKLIGRV-HAEDADEGINA--EITYFAPDDIPFTVD---PETGDVL 731
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T+ LD E+ D Y+ V A A VT+ + D D PVF ++YE + EN
Sbjct: 732 TKIVLDYEQNDEYKFVVTARDGAPDYRLATA-TVTVKVIDVEDEVPVFHQSSYEARVKEN 790
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI-GDSLDREKK 858
I +++ T D T Y + E+F +D+ TGV+K G +RE +
Sbjct: 791 ------IPDYTVLQVTADDPDTKKQITYMIKQGDTELFAIDQRTGVIKTTRGLDYERESQ 844
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
+ + V + S +++ + D ND P F +
Sbjct: 845 HILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSV 882
Score = 102 bits (244), Expect = 9e-20
Identities = 103/356 (28%), Positives = 163/356 (45%), Gaps = 27/356 (7%)
Query: 990 RYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
R F I ++ G + V R L E + ++L I A D G L +V + V D+ND P F
Sbjct: 620 RQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSGGLFSTATVNIKVTDINDKNPEFVG 679
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y F+V+E + R+++G+V A DAD G NA +TYF + D+PF + P TG +
Sbjct: 680 LPYEFSVKEGE-ARKLIGRVHAEDADEGINAEITYF---APDDIPFTVDPETGDVLTKIV 735
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLEWKHPEA 1165
LD E D+Y V ARD G DV D P F+ +++ ++ P+
Sbjct: 736 LDYEQNDEYKFVVTARD-GAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENIPDY 794
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
L + P K I G T T I GL +R++Q
Sbjct: 795 TVL-----QVTADDPDTKKQITYMIKQGDTELFAIDQRTGVIKTTRGLDY----ERESQH 845
Query: 1226 NLGLPSLSSTAILMVTVADVPDEV-EMSD-KPVFISRYYELEIEENVNAPVELVSLNLTE 1283
L + ++ +T+ L + V V +++D PVF S + +++++ +++L T+
Sbjct: 846 ILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPITLDDDIPIGTTVINLIATD 905
Query: 1284 H---YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT-YEVIVRA 1335
++RY I+ + + F+IDP G L VR R+ DT Y+V VRA
Sbjct: 906 SDGTAPGNQVRYEIVGRGIAN--KYFMIDPDTGVL-RVRDDLRKETDTEYQVDVRA 958
Score = 99.1 bits (236), Expect = 8e-19
Identities = 115/435 (26%), Positives = 194/435 (44%), Gaps = 42/435 (9%)
Query: 445 VEVTLLDA-NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
VEV ++ N +PVF +YE + A + + + V AVDP+ N V Y + +
Sbjct: 562 VEVNVIPGPNTRSPVF-QQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIVSGN 617
Query: 504 NLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+L F I +G ++V E R+ L ++A D S +S A V I+VT
Sbjct: 618 DLR---QFAIGDKSGVITVIRKLDREDLTRYQLLIKAED-----SGGLFSTATVNIKVTD 669
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N P+F+G PYEF V +G++ DA E ++ ++ + + +PF
Sbjct: 670 INDKN----PEFVGLPYEFSVKEGEA-RKLIGRVHAEDADE--GINAEITYFAPDDIPFT 722
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGA 680
V+ +G + L Y F A + + T TV V+DV DE V + +
Sbjct: 723 VDPETGDVLTKIVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSS 782
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIF 739
+ VKEN + Q+ + + + ++I +Q T+ AI + G I
Sbjct: 783 YEA---RVKENIPDYTVLQVTADDPDT-----KKQITYMI--KQGDTELFAIDQRTGVIK 832
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T + LD E+ + + + N + G+ +V + ++D ND PPVF + ++
Sbjct: 833 TTRGLDYERESQHILIIGTVENTSDLPGSTT-RVVVNVQDVNDIPPVFTSVPRPITLDDD 891
Query: 800 SKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEG--KEMFDVDENTGVVKFIGDSLDRE 856
IGT + N+I ATD+D Y + G G + F +D +TGV++ + D L +E
Sbjct: 892 IPIGTTV--INLI-ATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLR-VRDDLRKE 947
Query: 857 KKIMYKLSLVARDTG 871
Y++ + A D G
Sbjct: 948 TDTEYQVDVRAYDMG 962
Score = 94.3 bits (224), Expect = 2e-17
Identities = 132/508 (25%), Positives = 206/508 (40%), Gaps = 47/508 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + D ND NP FV YEFS+K + +IG+V A D D G N + Y
Sbjct: 657 LFSTATVNIKVTDINDKNPEFV-GLPYEFSVK-EGEARKLIGRVHAEDADEGINAEITYF 714
Query: 499 LQRTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
PF ++P TG V + + V A D + R + A VT
Sbjct: 715 APD------DIPFTVDPETGDVLTKIVLDYEQNDEYKFVVTARD---GAPDYRLATATVT 765
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
++V + ++P F + YE V N+ T V Q+ +D + ++Y + G E
Sbjct: 766 VKVI----DVEDEVPVFHQSSYEARVKENIPDYT-VLQVTADDPDTKKQITYMIKQGDTE 820
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERG 674
FA+++R+GVI L Y R + EN + T V+V DVND
Sbjct: 821 --LFAIDQRTGVIKTTRGLD-YERESQHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPP 877
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAIA 733
V PI + G + + T+ G GN VR+ I + I
Sbjct: 878 V-FTSVPRPITLD-DDIPIGTTVINLIATDSD---GTAPGNQVRYEIVGRGIANKYFMID 932
Query: 734 ED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV----FE 788
D G + + L +E Y++ V A ++ G + + V +Y+ PP F
Sbjct: 933 PDTGVLRVRDDLRKETDTEYQVDVRA-YDMGEPQLSSVTTVPVYVRHVATVPPEIGLGFA 991
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD---VDENTGV 845
+Y + E++ T IK+ II + D T L G ++F+ +E
Sbjct: 992 ENSYNVEVPEDAGDNTLIKIITIINSHAHD--TTPLKCEIYSGNEDDLFEAGVTEERNCA 1049
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE----LIIMIGDENDNKPEFNQIEENSK 901
+K +LD E Y++ + GL + + I + D NDNKPEF E + K
Sbjct: 1050 LKLKKGALDYETTESYQVKIKLESLSGLLNSGRNTTMVKIQVVDVNDNKPEFIFPENDLK 1109
Query: 902 V---RIHRETKLNGTAGFTIIEVKPKNK 926
+ R + G T+I+VK +K
Sbjct: 1110 LSRGRYFAAIPRSAQFGSTVIQVKAHDK 1137
Score = 91.9 bits (218), Expect = 1e-16
Identities = 178/692 (25%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 249 VNGS-LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
+NG L L + LD D E NL F L Q N K V + + D+NDN P+F
Sbjct: 57 LNGKRLQLLEPLDRDDE-NLSHVVFQLSCTVKQTN---KKRTIPVIVRVSDINDNAPKFI 112
Query: 308 VDFYNISIVENLPNGFSVLQ-VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
Y ++ E P G ++ + V+A D D G NG Y + G I G RN+
Sbjct: 113 NTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEYSIAPGDGT-GIGNNDG--VGRNR 169
Query: 367 -TVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKV 425
T D + S+ + + T V D +R ++ L ++ + F
Sbjct: 170 ITTADGYGYFSINLPHQGQVT----VNRTLDFERTQRYLVTILASDRA-RNVSERFTSTT 224
Query: 426 GTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI---GKV 482
T T NI D+Q SF+ LLD NP Y S+ S G + K+
Sbjct: 225 -TLTVNIRDDDDQDPSFIYQGCMLLDGACINPE------YSASVSSGVLSGILNISPEKI 277
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASD 540
+AVD D N + Y + F+INPNTG V A + R + ++A +
Sbjct: 278 QAVDMD-SINAPIHYSFLSGNPPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVE 336
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV----GQ-- 594
+R + A +TI V + N P I + E +V N IGT V G
Sbjct: 337 VS---EAKRSATAKLTITV-KPVDSNPPIIT---ASSIEGFVDENAPIGTKVIDKDGDPI 389
Query: 595 -IRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM---YDFEAVAL 650
+ V+DA D + +E F + SG++ V ++ + P + F+ VA
Sbjct: 390 VLTVSDADLGPDDPKPA-YSFELTTNFFAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAR 448
Query: 651 QENANLSIVTNATVHVV-DVNDERGVL--------LKGAHSPIIFHVKENSAGAAIGQIF 701
++ + + V ++ DVND +L G ++ V+ G+
Sbjct: 449 EKTGVAASAPLSFVVILNDVNDNAPMLPMIPPITVQAGETKKVVTKVEATDNDE--GENA 506
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN 761
S + + G +F I + V + + G F+ +K Y T++ E N
Sbjct: 507 EITYSIYHVSNNGLHKFKIDPRTGVIESVRKLNAGEQFSITVQATDKGGKYSQTIV-EVN 565
Query: 762 KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT 821
VI G N PVF+ YE + E + I + + I+ A D +
Sbjct: 566 --VIPGP------------NTRSPVFQQPVYEVQVSEGASINSTM---TIVHAVDPE--- 605
Query: 822 NALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI 880
N Y++ G F + + +GV+ I LDRE Y+L + A D+GGL S A +
Sbjct: 606 NDPVSYSIVSGNDLRQFAIGDKSGVITVIR-KLDREDLTRYQLLIKAEDSGGLFSTATVN 664
Query: 881 IMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
I + D ND PEF + V+ KL G
Sbjct: 665 IKVTDINDKNPEFVGLPYEFSVKEGEARKLIG 696
Score = 88.6 bits (210), Expect = 1e-15
Identities = 125/492 (25%), Positives = 191/492 (38%), Gaps = 74/492 (15%)
Query: 930 DVDQLGPLF--LIPENIPIGTT---IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
DV+ P+ + P + G T + K+ A D D G N +I Y +Y +S +
Sbjct: 467 DVNDNAPMLPMIPPITVQAGETKKVVTKVEATDNDEGENAEITYS----IY----HVSNN 518
Query: 985 ALEVKRYFVINERHGHVIVARSLPPESEFRLNISALD-GGNLNDNISVRVFVKDVNDHFP 1043
L F I+ R G + R L +F + + A D GG + I + N P
Sbjct: 519 GLHK---FKIDPRTGVIESVRKLNAGEQFSITVQATDKGGKYSQTIVEVNVIPGPNTRSP 575
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
VF++ Y V E + V A D + N ++Y I + F I +GV++
Sbjct: 576 VFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIVSGNDLRQFAIGDKSGVIT 632
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
V +LDRE +Y L + A D+G D+ND +P+F K
Sbjct: 633 VIRKLDREDLTRYQLLIKAEDSG---GLFSTATVNIKVTDINDKNPEFVGLPYEFSVKEG 689
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI---GNGNGLILYSLPQ 1220
EA +L V+ +E I + +D F G+ L L
Sbjct: 690 EARKLIGR---------VHAEDADEG--INAEITYFAPDDIPFTVDPETGDVLTKIVLDY 738
Query: 1221 RKNQQ-------NLGLPSLS-STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
+N + G P +TA + V V DV DEV PVF YE ++EN+
Sbjct: 739 EQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEV-----PVFHQSSYEARVKENI-- 791
Query: 1273 PVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
P V + + K Y++ + DT++ F ID R G + R D
Sbjct: 792 PDYTVLQVTADDPDTKKQITYMIKQGDTEL---FAIDQRTGVIKTTRGLD---------- 838
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIP 1392
Y RE H++ + + +VVV ++DVND P FT+ RP+ +
Sbjct: 839 -------YERESQHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPI--TLD 889
Query: 1393 TTAPFGYQVMQL 1404
P G V+ L
Sbjct: 890 DDIPIGTTVINL 901
Score = 63.7 bits (148), Expect = 4e-08
Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 14/171 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA+D + + Y ++SGND + F++ +G + + ++LD + + L ++
Sbjct: 599 VHAVDPE---NDPVSYSIVSGNDLRQFAIGDKSGVITVIRKLDRE-----DLTRYQLLIK 650
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A T A V I++ D+ND PEF Y S+ E + +V A D D+G
Sbjct: 651 AEDSGGLFST--ATVNIKVTDINDKNPEFVGLPYEFSVKEGEARKL-IGRVHAEDADEGI 707
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
N E TY D F++DP +G V + VLD E + + V A++ P
Sbjct: 708 NAEITYFAPDDI-PFTVDPETG--DVLTKIVLDYEQNDEYKFVVTARDGAP 755
Score = 61.7 bits (143), Expect = 2e-07
Identities = 110/445 (24%), Positives = 183/445 (41%), Gaps = 49/445 (11%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN-GQ 965
E K + TA TI VKP + + + EN PIGT +I + + ++
Sbjct: 339 EAKRSATAKLTIT-VKPVDSNPPIITASSIEGFVDENAPIGTKVIDKDGDPIVLTVSDAD 397
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALD--GG 1023
+ + Y + A++ V+NE + + R P FR + A + G
Sbjct: 398 LGPDDPKPAYSFELTTNFFAIDPSGMLVVNEEN----LDRDPPSPGRFRFQVVAREKTGV 453
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+ +S V + DVND+ P+ V+ + T++V+ KV+ATD D G+NA +TY
Sbjct: 454 AASAPLSFVVILNDVNDNAPMLPMI-PPITVQAGE-TKKVVTKVEATDNDEGENAEITYS 511
Query: 1084 I-QPSDTDL-PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
I S+ L F+I P TGV+ +L+ +++ +TV A D G
Sbjct: 512 IYHVSNNGLHKFKIDPRTGVIESVRKLN--AGEQFSITVQATDKG--GKYSQTIVEVNVI 567
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA 1201
N SP F + E + E +++ + + A EN P+ ++ V
Sbjct: 568 PGPNTRSPVFQ--QPVYEVQVSEGASINS-------TMTIVHAVDPENDPVSYSI--VSG 616
Query: 1202 ND-TDF-IGNGNGLI-LYSLPQRKNQQNLGL-------PSLSSTAILMVTVADVPDEVEM 1251
ND F IG+ +G+I + R++ L L STA + + V D+ D+
Sbjct: 617 NDLRQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSGGLFSTATVNIKVTDINDK--- 673
Query: 1252 SDKPVFISRYYELEIEE-NVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
P F+ YE ++E + V + N ++ Y+ DI F +DP
Sbjct: 674 --NPEFVGLPYEFSVKEGEARKLIGRVHAEDADEGINAEITYFA----PDDI--PFTVDP 725
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRA 1335
G + D E D Y+ +V A
Sbjct: 726 ETGDVLTKIVLDYEQNDEYKFVVTA 750
Score = 55.6 bits (128), Expect = 1e-05
Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D G+ A + Y D F++D G + + LD + Q + + V
Sbjct: 698 VHAEDADEGINAEITY---FAPDDIPFTVDPETGDVLTKIVLDYE-----QNDEYKFVVT 749
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + A A V ++++D+ D +P F Y + EN+P+ ++VLQV A D D +
Sbjct: 750 ARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENIPD-YTVLQVTADDPDTKK 808
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSL 377
+ + D + F+ID R+G + +RE+ L
Sbjct: 809 QITYMIKQGDTE-LFAIDQRTGVIKTTRGLDYERESQHIL 847
Score = 54.4 bits (125), Expect = 2e-05
Identities = 54/180 (30%), Positives = 86/180 (47%), Gaps = 21/180 (11%)
Query: 231 LRYELISGNDRKLFSL---DSVNGSLFLEK-ELDLDAEHNLQANTFVLQVQASQLNNPLK 286
L+ E+ SGN+ LF + N +L L+K LD + + Q L+ + LN+
Sbjct: 1025 LKCEIYSGNEDDLFEAGVTEERNCALKLKKGALDYETTESYQVK-IKLESLSGLLNSGRN 1083
Query: 287 TAQARVEIELLDLNDNLPEF---EVDF------YNISIVENLPNGFSVLQVMATDKDQGE 337
T V+I+++D+NDN PEF E D Y +I + G +V+QV A DKD G+
Sbjct: 1084 TTM--VKIQVVDVNDNKPEFIFPENDLKLSRGRYFAAIPRSAQFGSTVIQVKAHDKDNGK 1141
Query: 338 NGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK-ETNPSVVGTF 394
G+ Y++ +G+ F++D SG +R D + L K + NP+ F
Sbjct: 1142 YGKLEYRILGGRGSDYFAMDTSSG--IIRTTATFDNVDPAELPFKFDVRVRDNPNSTDNF 1199
Score = 49.6 bits (113), Expect = 6e-04
Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTI 140
+ V V + D+NDN P F++TPY TV ELTP G F ++A + G+
Sbjct: 95 IPVIVRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVA---------VDADAGVNG 145
Query: 141 FKDIRAFDRDKPNTPNSD--VHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ 198
+ D N+D I + + G+F++ H+ + + + LD++ + +
Sbjct: 146 IVEYSIAPGDGTGIGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFER-TQRYL 204
Query: 199 LVIMASGK 206
+ I+AS +
Sbjct: 205 VTILASDR 212
Score = 47.6 bits (108), Expect = 0.003
Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 9/152 (5%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+I D +LF++D G + + LD + E + +L + + + L + RV +
Sbjct: 813 MIKQGDTELFAIDQRTGVIKTTRGLDYERE-----SQHILIIGTVENTSDLPGSTTRVVV 867
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLDDPKGA-- 351
+ D+ND P F I++ +++P G +V+ ++ATD D G + Y++ A
Sbjct: 868 NVQDVNDIPPVFTSVPRPITLDDDIPIGTTVINLIATDSDGTAPGNQVRYEIVGRGIANK 927
Query: 352 -FSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
F IDP +G L VR+ + + + ++ Y
Sbjct: 928 YFMIDPDTGVLRVRDDLRKETDTEYQVDVRAY 959
Score = 45.6 bits (103), Expect = 0.011
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
L H+++ ++ V + K + V+VR+ D+NDN+PKF N P T +P P G + +
Sbjct: 75 LSHVVFQLSCTVKQTNKKRTIPVIVRVSDINDNAPKFI--NTPYETTVPELTPVGSTIFK 132
Score = 41.5 bits (93), Expect = 0.17
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 992 FVINERHGHVIVARSLPPESEFR--LNISALDGGNLNDNISVRVFV--KDVNDHFPVFKK 1047
F I++R G + R L E E + L I ++ + + RV V +DVND PVF
Sbjct: 822 FAIDQRTGVIKTTRGLDYERESQHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTS 881
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF--IQPSDTDLPFEISPLTGVLSVN 1105
+++ + + ATD+D N + + + F I P TGVL V
Sbjct: 882 VPRPITLDDDIPIGTTVINLIATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVR 941
Query: 1106 GELDRETEDKYILTVVARDNG 1126
+L +ET+ +Y + V A D G
Sbjct: 942 DDLRKETDTEYQVDVRAYDMG 962
Score = 41.1 bits (92), Expect = 0.23
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F++D + E+ LD D F QV A + +A + L D+NDN
Sbjct: 416 FAIDPSGMLVVNEENLDRDPP---SPGRFRFQVVAREKTGVAASAPLSFVVILNDVNDNA 472
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSG 359
P + I++ V +V ATD D+GEN E TY + ++ F IDPR+G
Sbjct: 473 PMLPM-IPPITVQAGETKKV-VTKVEATDNDEGENAEITYSIYHVSNNGLHKFKIDPRTG 530
Score = 40.3 bits (90), Expect = 0.40
Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 23/151 (15%)
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK-VDATDADFGQNANLTY 1082
N I V V V D+ND+ P F T Y V E + K V A DAD G N + Y
Sbjct: 90 NKKRTIPVIVRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEY 149
Query: 1083 FIQPSD-TDLP------------------FEIS-PLTGVLSVNGELDRETEDKYILTVVA 1122
I P D T + F I+ P G ++VN LD E +Y++T++A
Sbjct: 150 SIAPGDGTGIGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILA 209
Query: 1123 RD--NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D D +D P F
Sbjct: 210 SDRARNVSERFTSTTTLTVNIRDDDDQDPSF 240
Score = 37.9 bits (84), Expect = 2.1
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
Query: 29 RTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFD-EGDDLVRIGAGLNQISAYLSVT--- 84
+ ++ ++ Q L D V+K G D++ E ++ IG N S T
Sbjct: 807 KKQITYMIKQGDTELFAIDQRTGVIKTTRGLDYERESQHILIIGTVENTSDLPGSTTRVV 866
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
V ++DVND P+F P +T+D+ P G
Sbjct: 867 VNVQDVNDIPPVFTSVPRPITLDDDIPIG 895
>UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n=3;
Xenopus tropicalis|Rep: UPI00006A1F6A UniRef100 entry -
Xenopus tropicalis
Length = 644
Score = 125 bits (301), Expect = 1e-26
Identities = 125/444 (28%), Positives = 197/444 (44%), Gaps = 35/444 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V+LLD NDN+PVF P Y +++ N + + V A DPDLG NG + Y
Sbjct: 213 LSSTAKVIVSLLDVNDNSPVFYPVQ-YFANIQENEPPASFVATVTASDPDLGINGTIRYS 271
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVT 556
++ TS F+++P TG +S + E + A L V A+D S ++ A+VT
Sbjct: 272 IRAGD----TSKFQVHPETGAISTKAALDREEKTAYQLQVVATDGGGLQS---HNHAIVT 324
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG-TSVGQIRVNDAFEQND--VSYDLLHG 613
I V T+ N P F Y F S + T V ++ +D E N+ +SY ++ G
Sbjct: 325 ITVL-DTQDNP---PSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKG 380
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDE 672
EE F ++ +G + +V L Y A+ A LS + ++ V+D ND
Sbjct: 381 NEE-KHFTMDSSTGQVALVGRLDYEATASYSLIIQAVDSGAVPLSATSTLSIEVLDENDN 439
Query: 673 RGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
K A + V EN G + + T+ S ++ + I +
Sbjct: 440 SPSFPKAA---LFVDVVENMRVGELVSSVTATDSDS---GDNADIHYSITGTNNHGTFSI 493
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G+IF K LD E + +Y++ + A+ +KG + V I + D NDNPP F
Sbjct: 494 SPNTGSIFLAKKLDFETQALYKLNITAK-DKGNPPRSSTMSVIIKVRDFNDNPPSF--PA 550
Query: 792 YEGFIMENS-KIGTEIKMDNI---IKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
F+ +N+ + + ++ I A D DEG+N Y + E F VD +G ++
Sbjct: 551 VPTFVSQNAFAADPSLAIGSVLSTITAFDPDEGSNGEIEYEIISGDTETFIVDRYSGDLR 610
Query: 848 FIGDSLDREKKIMYKLSLVARDTG 871
L ++Y L + A D G
Sbjct: 611 VAAPML--PSHLIYSLIVAATDLG 632
Score = 108 bits (260), Expect = 1e-21
Identities = 115/466 (24%), Positives = 193/466 (41%), Gaps = 41/466 (8%)
Query: 445 VEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
V +T+LD NDN+PVF P + E S + G+ I V A D D G N + Y + +
Sbjct: 107 VRITVLDINDNSPVFQEPHSKVEIS--EDLPPGSYICGVSASDGDTGLNANLRYSIVSGN 164
Query: 504 NLTITSPFKINPNTGTVSVAESPIL---------EGRHALFVEASDQPANPSERRYSLAV 554
L F I+ N+G + + + R L + A+D P + V
Sbjct: 165 KL---GWFSISENSGLLDPLSGKLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIV 221
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
++V + P F Y + N + V + +D + Y +
Sbjct: 222 SLLDVNDNS-------PVFYPVQYFANIQENEPPASFVATVTASDPDLGINGTIRYSIRA 274
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVN 670
G + F V +G I+ L R + Y + VA + L +A T+ V+D
Sbjct: 275 G--DTSKFQVHPETGAISTKAALDREEKTAYQLQVVAT-DGGGLQSHNHAIVTITVLDTQ 331
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D +G++S + + + Q+ + S + G + + I +
Sbjct: 332 DNPPSFSQGSYS----FASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKGNEEKHFT 387
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G + LD E Y + +I + G + + ++I + DENDN P F A
Sbjct: 388 MDSSTGQVALVGRLDYEATASYSL-IIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPKA 446
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFI 849
++EN ++G ++ + + ATD+D G NA Y++ G F + NTG + F+
Sbjct: 447 ALFVDVVENMRVG---ELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNTGSI-FL 502
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
LD E + +YKL++ A+D G SS +II + D NDN P F
Sbjct: 503 AKKLDFETQALYKLNITAKDKGNPPRSSTMSVIIKVRDFNDNPPSF 548
Score = 101 bits (243), Expect = 1e-19
Identities = 120/476 (25%), Positives = 198/476 (41%), Gaps = 63/476 (13%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ P+F P E++P G+ I ++A D D+GLN +RY + +KL
Sbjct: 112 LDINDNSPVFQEPHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSI-----VSGNKL 166
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKD 1037
++ + +++ G + L E + R L I A D G L+ V V + D
Sbjct: 167 GWFSIS-ENSGLLDPLSGKLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLD 225
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND+ PVF Y N++E + + V A+D D G N + Y I+ DT F++ P
Sbjct: 226 VNDNSPVFYPVQYFANIQENEPPASFVATVTASDPDLGINGTIRYSIRAGDTS-KFQVHP 284
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF----YA 1153
TG +S LDRE + Y L VVA D G D DN P F Y+
Sbjct: 285 ETGAISTKAALDREEKTAYQLQVVATDGG-GLQSHNHAIVTITVLDTQDNPPSFSQGSYS 343
Query: 1154 FDELLEWKHPEADELS------NHNFESVMMIPVYKATIEENAPIGTTVAKV-FANDTDF 1206
F + E L + ++ + K E++ + ++ +V D+
Sbjct: 344 FASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKGNEEKHFTMDSSTGQVALVGRLDY 403
Query: 1207 IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEI 1266
+ YSL + + G LS+T+ L + V D E + P F +++
Sbjct: 404 EATAS----YSLIIQ--AVDSGAVPLSATSTLSIEVLD-----ENDNSPSFPKAALFVDV 452
Query: 1267 EEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
EN V V V+ ++ +N + Y I N+ TF I P G+++L + D E
Sbjct: 453 VENMRVGELVSSVTATDSDSGDNADIHYSITGTNN---HGTFSISPNTGSIFLAKKLDFE 509
Query: 1325 VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ Y++ + A+D + V+++++D NDN P F
Sbjct: 510 TQALYKLNI-----------------TAKDKGNPPRSSTMSVIIKVRDFNDNPPSF 548
Score = 95.1 bits (226), Expect = 1e-17
Identities = 90/349 (25%), Positives = 144/349 (41%), Gaps = 26/349 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL---- 128
G +S+ V V + DVNDN P+F Y + E P +F+ + P L
Sbjct: 209 GTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPA--SFVATVTASDPDLGING 266
Query: 129 TIPLTVPRGLT----IFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLL 183
TI ++ G T + + A Y + V D G SH ++
Sbjct: 267 TIRYSIRAGDTSKFQVHPETGAISTKAALDREEKTAYQLQVVATDGGGL---QSHNHAIV 323
Query: 184 LRKVLDYDAGDKEFQL--VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
VLD F AS + + + + D D G + Y ++ GN+
Sbjct: 324 TITVLDTQDNPPSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKGNEE 383
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
K F++DS G + L LD +A ++ L +QA +A + + IE+LD ND
Sbjct: 384 KHFTMDSSTGQVALVGRLDYEA-----TASYSLIIQAVDSGAVPLSATSTLSIEVLDEND 438
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
N P F + +VEN+ G V V ATD D G+N + Y + + G FSI P +G
Sbjct: 439 NSPSFPKAALFVDVVENMRVGELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNTG 498
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFADSQRIAKWRRQP 407
+ + + LD E + ++ + AK+ NP T + ++ + P
Sbjct: 499 SIFLAKK--LDFETQALYKLNITAKDKGNPPRSSTMSVIIKVRDFNDNP 545
Score = 87.0 bits (206), Expect = 3e-15
Identities = 59/174 (33%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-----LEKELDLDAEHNLQANTF 272
+ A D D G+ A LRY ++SGN FS+ +G L L DLD E Q +
Sbjct: 143 VSASDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSGKLSNRADLDRE---QQDRC 199
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
LQ+ A+ L P ++ A+V + LLD+NDN P F Y +I EN P V V A+D
Sbjct: 200 TLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPASFVATVTASD 259
Query: 333 KDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G NG Y + F + P +G + + LDRE ++ +++V A +
Sbjct: 260 PDLGINGTIRYSIRAGDTSKFQVHPETG--AISTKAALDREEKTAYQLQVVATD 311
Score = 77.0 bits (181), Expect = 4e-12
Identities = 59/192 (30%), Positives = 89/192 (46%), Gaps = 13/192 (6%)
Query: 706 SSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI 765
S + GN G F I+ + D ++ G + + LDRE++D + ++A + G
Sbjct: 159 SIVSGNKLG--WFSISENSGLLDPLS----GKLSNRADLDREQQDRCTLQILAT-DLGTP 211
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ +V + + D NDN PVF Y I EN + + + A+D D G N
Sbjct: 212 PLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPASFVAT---VTASDPDLGINGTI 268
Query: 826 MYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG- 884
Y++ F V TG + +LDRE+K Y+L +VA D GGL S I+ I
Sbjct: 269 RYSIRAGDTSKFQVHPETGAISTKA-ALDREEKTAYQLQVVATDGGGLQSHNHAIVTITV 327
Query: 885 -DENDNKPEFNQ 895
D DN P F+Q
Sbjct: 328 LDTQDNPPSFSQ 339
Score = 76.2 bits (179), Expect = 7e-12
Identities = 60/210 (28%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL 1007
T ++++++ D+D G NG I Y +++F ++ G V + L
Sbjct: 355 TQVLRVSSSDVDEGNNGLISYSIMKG-------------NEEKHFTMDSSTGQVALVGRL 401
Query: 1008 PPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV 1063
E+ + L I A+D G L+ ++ + V D ND+ P F K +V E +
Sbjct: 402 DYEATASYSLIIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPKAALFVDVVENMRVGEL 461
Query: 1064 LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
+ V ATD+D G NA++ Y I ++ F ISP TG + + +LD ET+ Y L + A+
Sbjct: 462 VSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNTGSIFLAKKLDFETQALYKLNITAK 521
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
D G D NDN P F A
Sbjct: 522 DKG-NPPRSSTMSVIIKVRDFNDNPPSFPA 550
Score = 72.5 bits (170), Expect = 8e-11
Identities = 97/364 (26%), Positives = 144/364 (39%), Gaps = 35/364 (9%)
Query: 992 FVINERHGHVIVARSLPPESEFR--LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F IN G + ++ ES +N+ L VR+ V D+ND+ PVF++
Sbjct: 67 FSINSTTGSIYTTSNIDRESLISDVINLVVLSSQPTYPT-EVRITVLDINDNSPVFQEPH 125
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS-------PLTGVL 1102
+ E + V A+D D G NANL Y I + F IS PL+G L
Sbjct: 126 SKVEISEDLPPGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSGKL 185
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL--LEW 1160
S +LDRE +D+ L ++A D G DVNDNSP FY ++
Sbjct: 186 SNRADLDREQQDRCTLQILATDLG-TPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQE 244
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL-----IL 1215
P A ++ + TI + G T +T I L
Sbjct: 245 NEPPASFVATVTASDPDL--GINGTIRYSIRAGDTSKFQVHPETGAISTKAALDREEKTA 302
Query: 1216 YSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL----EIEENVN 1271
Y L Q GL S + AI+ +TV D D + P F Y E+ N+
Sbjct: 303 YQL-QVVATDGGGLQS-HNHAIVTITVLDTQD-----NPPSFSQGSYSFASISELASNMT 355
Query: 1272 APVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ + S ++ E N + Y I+ N+ + F +D G + LV D E +Y +
Sbjct: 356 QVLRVSSSDVDEG-NNGLISYSIMKGNE---EKHFTMDSSTGQVALVGRLDYEATASYSL 411
Query: 1332 IVRA 1335
I++A
Sbjct: 412 IIQA 415
Score = 63.7 bits (148), Expect = 4e-08
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 11/152 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A + Y + N+ FS+ GS+FL K+LD + + + L +
Sbjct: 465 VTATDSDSGDNADIHYSITGTNNHGTFSISPNTGSIFLAKKLDFETQA-----LYKLNIT 519
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFE-----VDFYNISIVENLPNGFSVLQVMATD 332
A NP +++ V I++ D NDN P F V + +L G + + A D
Sbjct: 520 AKDKGNPPRSSTMSVIIKVRDFNDNPPSFPAVPTFVSQNAFAADPSLAIGSVLSTITAFD 579
Query: 333 KDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTV 363
D+G NGE Y+ + F +D SG L V
Sbjct: 580 PDEGSNGEIEYEIISGDTETFIVDRYSGDLRV 611
Score = 62.9 bits (146), Expect = 7e-08
Identities = 47/150 (31%), Positives = 73/150 (48%), Gaps = 15/150 (10%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LFS++S GS++ +D ++ L ++ L V +SQ P + V I +LD+NDN
Sbjct: 66 LFSINSTTGSIYTTSNIDRES---LISDVINLVVLSSQPTYPTE-----VRITVLDINDN 117
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGW 360
P F+ + I E+LP G + V A+D D G N Y + + G FSI SG
Sbjct: 118 SPVFQEPHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGL 177
Query: 361 L-----TVRNQTVLDREAHSSLRMKVYAKE 385
L + N+ LDRE +++ A +
Sbjct: 178 LDPLSGKLSNRADLDREQQDRCTLQILATD 207
Score = 62.9 bits (146), Expect = 7e-08
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 20/173 (11%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY--QVTIYIEDENDNPPVFEHATYE 793
G+I+T +DRE + N V+S Y +V I + D NDN PVF+ +
Sbjct: 74 GSIYTTSNIDRES------LISDVINLVVLSSQPTYPTEVRITVLDINDNSPVFQEPHSK 127
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDS 852
I E+ G+ I + A+D D G NA Y++ K F + EN+G++ +
Sbjct: 128 VEISEDLPPGSYICG---VSASDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSGK 184
Query: 853 L------DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
L DRE++ L ++A D G LSS A++I+ + D NDN P F ++
Sbjct: 185 LSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQ 237
Score = 54.4 bits (125), Expect = 2e-05
Identities = 70/314 (22%), Positives = 127/314 (40%), Gaps = 22/314 (7%)
Query: 368 VLDREAHSSLRMKVYAKETNPSVVGTFADSQRI---AKWRRQPLETNAPLEKTTYVFPDK 424
+ + E +S V A + + + GT S R +K++ P ET A K +K
Sbjct: 242 IQENEPPASFVATVTASDPDLGINGTIRYSIRAGDTSKFQVHP-ETGAISTKAALDREEK 300
Query: 425 VGTKTENIEYYDEQLMSFVN--VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
+ + + L S + V +T+LD DN P F + S+ A T + +V
Sbjct: 301 TAYQLQVVATDGGGLQSHNHAIVTITVLDTQDNPPSFSQGSYSFASISELASNMTQVLRV 360
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASD 540
+ D D G NG++ Y + + + F ++ +TG V++ E ++L ++A D
Sbjct: 361 SSSDVDEGNNGLISYSIMKGNE---EKHFTMDSSTGQVALVGRLDYEATASYSLIIQAVD 417
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--N 598
A P +L++ ++ N P P A V N+ +G V + +
Sbjct: 418 SGAVPLSATSTLSIEVLD----ENDNSPSFPK---AALFVDVVENMRVGELVSSVTATDS 470
Query: 599 DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLS 657
D+ + D+ Y + G F++ +G I + L + +Y A + N S
Sbjct: 471 DSGDNADIHYSITGTNNHGT-FSISPNTGSIFLAKKLDFETQALYKLNITAKDKGNPPRS 529
Query: 658 IVTNATVHVVDVND 671
+ + V D ND
Sbjct: 530 STMSVIIKVRDFND 543
Score = 52.0 bits (119), Expect = 1e-04
Identities = 61/217 (28%), Positives = 93/217 (42%), Gaps = 24/217 (11%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
IEV +N + + + EN+ +G + + A D DSG N I Y
Sbjct: 431 IEVLDENDNSPSFPKAALFVDVVENMRVGELVSSVTATDSDSGDNADIHY---------- 480
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVF 1034
S F I+ G + +A+ L E++ ++LNI+A D GN + +SV +
Sbjct: 481 ---SITGTNNHGTFSISPNTGSIFLAKKLDFETQALYKLNITAKDKGNPPRSSTMSVIIK 537
Query: 1035 VKDVNDHFPVFKK--TWYNFNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSDT 1089
V+D ND+ P F T+ + N A + VL + A D D G N + Y I DT
Sbjct: 538 VRDFNDNPPSFPAVPTFVSQNAFAADPSLAIGSVLSTITAFDPDEGSNGEIEYEIISGDT 597
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ F + +G L V + + Y L V A D G
Sbjct: 598 E-TFIVDRYSGDLRVAAPM-LPSHLIYSLIVAATDLG 632
Score = 37.9 bits (84), Expect = 2.1
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
A+D D+GIN IRY I +F + P +G + AAL R+
Sbjct: 257 ASDPDLGINGTIRYSIRAGDTSKFQVHPETGAISTKAALDRE 298
>UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|Rep:
Protocadherin 15a - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1796
Score = 125 bits (301), Expect = 1e-26
Identities = 132/465 (28%), Positives = 206/465 (44%), Gaps = 41/465 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V++ ++DANDN P F + Y + +N G + ++ A D D G NG++ Y +
Sbjct: 498 VTVDILVIDANDNTPTFAQVS-YSVEIFTNMLPGETVLQLMAQDADAGLNGLITYAILAG 556
Query: 503 SNLTITSPFKINPNTGTVSVAESPILE-GR-HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F IN TG +++A +L GR +AL V A+D A +ERR S+ V IEV
Sbjct: 557 DH----GDFIINNRTGRITLAPGVMLTVGRSYALTVRAADN-APDTERRSSITTVYIEV- 610
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P F Y + + IG + ++ D E + ++Y + G + V F
Sbjct: 611 --LPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDR-ELDPITYRIETGDPQEV-F 666
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLK 678
+ G++ + L R Y + + + ++ ATV +V DVND
Sbjct: 667 NLSRTIGLLLLAKPLDRETIDQY--RLIVTASDGHPGGISTATVSIVITDVNDNDPTF-- 722
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
P V+E A +GQ+ T+ G G VR+ + + + +I G+I
Sbjct: 723 DLTLPRNLTVREEEANVFVGQVRATDPD---GGLNGQVRYRLLSFASL---FSINSTGSI 776
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHATYEGFI 796
FT PLDRE R R +I E + G + +T+ +E D NDN PVF Y +
Sbjct: 777 FTAVPLDRETRS--RYDLIVEASDGAVDPRRT-TITLLVEVLDINDNSPVFSQPVYTVNV 833
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
EN+ G+ I + A DAD +N + ++F V+ TGV+ + +LD E
Sbjct: 834 PENTPAGSIILR---LTAVDADLVSNVTYRIKT-EAALQLFAVNRLTGVISVL-QALDFE 888
Query: 857 K----KIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEFNQ 895
Y + A D GG+ A + + I D ND P F Q
Sbjct: 889 SLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDFSPVFRQ 933
Score = 94.7 bits (225), Expect = 2e-17
Identities = 119/468 (25%), Positives = 199/468 (42%), Gaps = 55/468 (11%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + V +LD NDN+PVF +Y ++ N G++I ++ AVD DL N V Y ++
Sbjct: 808 ITLLVEVLDINDNSPVF-SQPVYTVNVPENTPAGSIILRLTAVDADLVSN--VTYRIKTE 864
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEG------RHALFVEASDQPANPSERRYSLAVVT 556
+ L + F +N TG +SV ++ E + VEA D A V+
Sbjct: 865 AALQL---FAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPP---GTATVS 918
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ +T + P F A Y+ V N GT + + D + + + ++
Sbjct: 919 VRITDMNDFS----PVFRQALYKGLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRVDQ 974
Query: 617 ------GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
G F VE +G++ +L+ +P F+ V + + + TN T + V
Sbjct: 975 ELSPYSGSIFDVETDTGLVITKVNLNE--QPTTVFKLVVMAYDDGEPVKTNRTTVEITVL 1032
Query: 671 DERGVLLKGAHSPIIFHVKENSA-GAAIGQIFH--TNMSSIYGNGTGNVRFLIANQQDVT 727
+ + V EN+ G +G I TN + +Y +GN + +
Sbjct: 1033 QPSRIPIFTEEEYRFSPVSENAPIGTPVGLILAAATNTTVVYSIVSGNEGGVFTVNKST- 1091
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF------NKGVISGAGIYQVTIYIEDEN 781
G I+T K LD E Y + V A+ N S +V I ++DEN
Sbjct: 1092 --------GIIYTNKSLDYENVTSYVLRVQADSLTVILANLRAPSKTNTAKVFINVQDEN 1143
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMF 837
D+PPVF Y G + E++K T + I ATD D G + Y L EG++ F
Sbjct: 1144 DHPPVFSRQVYIGGVTEDTKTFTTVLK---IVATDVDTGNYSKMAYRLIIPPTTEGQDSF 1200
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDT--GGLSSEAELIIMI 883
++ TGV+K ++ +K +VA D GL+S+A++++ +
Sbjct: 1201 VIEPYTGVIK-SAIMFRNMRRSYFKFQVVATDDYGKGLTSKADVVVSV 1247
Score = 94.3 bits (224), Expect = 2e-17
Identities = 122/481 (25%), Positives = 208/481 (43%), Gaps = 57/481 (11%)
Query: 440 MSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+S V + + D NDN+P F +P NL ++N +G+V+A DPD G NG V
Sbjct: 703 ISTATVSIVITDVNDNDPTFDLTLPRNLTVREEEANV----FVGQVRATDPDGGLNGQVR 758
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
Y L L+ S F IN +TG++ A E R+ L VEASD +P +L V
Sbjct: 759 YRL-----LSFASLFSIN-STGSIFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLV 812
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+++ + P F Y V N G+ + ++ DA ++V+Y +
Sbjct: 813 EVLDINDNS-------PVFSQPVYTVNVPENTPAGSIILRLTAVDADLVSNVTYRIKTEA 865
Query: 615 EEGVPFAVEERSGVITVVDDLS----RYNRPMYDFEAVALQENANLSIVT-NATVHVVDV 669
+ FAV +GVI+V+ L Y FE AL L T +V + D+
Sbjct: 866 ALQL-FAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDM 924
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTD 728
ND V + + ++ E G I + + G VR+ + + +
Sbjct: 925 NDFSPVFRQALYKGLVAPNAEK--GTVITTVLAEDQDP-PGTPASKVRYRVDQELSPYSG 981
Query: 729 DIAIAE--DGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPP 785
I E G + T+ L+ + V+++ V+A + + V + ++T+ + P
Sbjct: 982 SIFDVETDTGLVITKVNLNEQPTTVFKLVVMAYDDGEPVKTNRTTVEITVL---QPSRIP 1038
Query: 786 VFEHATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENT 843
+F Y + EN+ IGT + + I+ A TN +Y++ G +F V+++T
Sbjct: 1039 IFTEEEYRFSPVSENAPIGTPVGL--ILAA-----ATNTTVVYSIVSGNEGGVFTVNKST 1091
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARD---------TGGLSSEAELIIMIGDENDNKPEFN 894
G++ + SLD E Y L + A ++ A++ I + DEND+ P F+
Sbjct: 1092 GII-YTNKSLDYENVTSYVLRVQADSLTVILANLRAPSKTNTAKVFINVQDENDHPPVFS 1150
Query: 895 Q 895
+
Sbjct: 1151 R 1151
Score = 74.5 bits (175), Expect = 2e-11
Identities = 129/552 (23%), Positives = 213/552 (38%), Gaps = 46/552 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L ++ +E+ +LD N+ P F S+ F +S++ VGT I + L + D
Sbjct: 380 LPAYSKLEIEILDENNQAPYFQQSSYRGFVSESSS-VGTTISASANLTAPLAIIALD-ND 437
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
++ T + + +N T ++ S I R ++ D+ + Y+L +V +
Sbjct: 438 IEETKDPQLK--ITLNEYTSIFTITTSGIT--RFLTLLKPVDREI---QTNYTLTLVATD 490
Query: 559 VTRGTKGNKPDI---------PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VS 607
+ ++ DI P F Y + +N+ G +V Q+ DA + ++
Sbjct: 491 GVQQSRPVTVDILVIDANDNTPTFAQVSYSVEIFTNMLPGETVLQLMAQDADAGLNGLIT 550
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ---ENANLSIVTNATV 664
Y +L G + G F + R+G IT+ + Y A + S +T +
Sbjct: 551 YAILAG-DHG-DFIINNRTGRITLAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYI 608
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V+ N++ P+ + E S IG I ++ R + Q
Sbjct: 609 EVLPPNNQ-----SPPRFPLQTYNLEISEAMRIGAILLNLQATDRELDPITYRIETGDPQ 663
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+V + G + KPLDRE D YR+ V A + G G V+I I D NDN
Sbjct: 664 EVFN--LSRTIGLLLLAKPLDRETIDQYRLIVTA--SDGHPGGISTATVSIVITDVNDND 719
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P F+ + + + ++ATD D G N Y L +F ++ +TG
Sbjct: 720 PTFDLTLPRNLTVREEEANVFVGQ---VRATDPDGGLNGQVRYRLLSFA-SLFSIN-STG 774
Query: 845 VVKFIGDSLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ F LDRE + Y L + A D + L++ + D NDN P F+Q V
Sbjct: 775 SI-FTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLVEVLDINDNSPVFSQ--PVYTV 831
Query: 903 RIHRETKLNG-TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
+ T T ++ + + L L N G I L ALD +S
Sbjct: 832 NVPENTPAGSIILRLTAVDADLVSNVTYRIKTEAALQLFAVNRLTG-VISVLQALDFESL 890
Query: 962 LNGQIRYEFNSE 973
G Y F E
Sbjct: 891 AAGNSTYTFEVE 902
Score = 71.3 bits (167), Expect = 2e-10
Identities = 113/450 (25%), Positives = 183/450 (40%), Gaps = 56/450 (12%)
Query: 943 NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI 1002
N+ G T+++L A D D+GLNG I Y L+ D + F+IN R G +
Sbjct: 526 NMLPGETVLQLMAQDADAGLNGLITYAI----------LAGDHGD----FIINNRTGRIT 571
Query: 1003 VARS--LPPESEFRLNISALDGGNLNDNIS--VRVFVKDV---NDHFPVFKKTWYNFNVE 1055
+A L + L + A D + S V+++ + N P F YN +
Sbjct: 572 LAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYIEVLPPNNQSPPRFPLQTYNLEIS 631
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
EA +L + ATD + +TY I+ D F +S G+L + LDRET D+
Sbjct: 632 EAMRIGAILLNLQATDRELDP---ITYRIETGDPQEVFNLSRTIGLLLLAKPLDRETIDQ 688
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y L V A D DVNDN P FD L P L+ E+
Sbjct: 689 YRLIVTASDG--HPGGISTATVSIVITDVNDNDP---TFDLTL----PR--NLTVREEEA 737
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGLPSLSS 1234
+ + +AT + G ++ + + F N G I ++P R+ + L +S
Sbjct: 738 NVFVGQVRATDPDGGLNGQVRYRLLSFASLFSINSTGSIFTAVPLDRETRSRYDLIVEAS 797
Query: 1235 TAIL---MVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKM 1290
+ T+ + + ++++D PVF Y + + EN A ++ L + +
Sbjct: 798 DGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVSNV 857
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y I E + F ++ G + ++++ D E + A Y+ E+ + +
Sbjct: 858 TYRIKTEAALQL---FAVNRLTGVISVLQALDFE-------SLAAGNSTYTFEVEALDH- 906
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
VL T V VRI D+ND SP F
Sbjct: 907 --GGVLPPGT---ATVSVRITDMNDFSPVF 931
Score = 64.9 bits (151), Expect = 2e-08
Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 11/170 (6%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
K +DRE + + + AE + G A ++ I I DEN+ P F+ ++Y GF+ E+S
Sbjct: 356 KSVDRELYQRFSLVIKAEQDNGHPLPA-YSKLEIEILDENNQAPYFQQSSYRGFVSESSS 414
Query: 802 IGTEIKMD-NI-----IKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIG--DS 852
+GT I N+ I A D D E T + E +F + +G+ +F+
Sbjct: 415 VGTTISASANLTAPLAIIALDNDIEETKDPQLKITLNEYTSIFTI-TTSGITRFLTLLKP 473
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+DRE + Y L+LVA D S + I++ D NDN P F Q+ + ++
Sbjct: 474 VDREIQTNYTLTLVATDGVQQSRPVTVDILVIDANDNTPTFAQVSYSVEI 523
Score = 64.9 bits (151), Expect = 2e-08
Identities = 56/214 (26%), Positives = 98/214 (45%), Gaps = 12/214 (5%)
Query: 151 KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMAS-GKRIH 209
KP + Y ++ DGH S+ +++ V D D F L + + R
Sbjct: 679 KPLDRETIDQYRLIVTASDGHPGGISTATVSIVITDVND---NDPTFDLTLPRNLTVREE 735
Query: 210 KEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA 269
+ +F + A D D G+ +RY L+S LFS++S GS+F LD +
Sbjct: 736 EANVFVGQVRATDPDGGLNGQVRYRLLSF--ASLFSINST-GSIFTAVPLDRETR----- 787
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ + L V+AS + + +E+LD+NDN P F Y +++ EN P G +L++
Sbjct: 788 SRYDLIVEASDGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLT 847
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
A D D N + + + F+++ +G ++V
Sbjct: 848 AVDADLVSNVTYRIKTEAALQLFAVNRLTGVISV 881
Score = 64.9 bits (151), Expect = 2e-08
Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 7/137 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKT 287
T+ Y ++SGN+ +F+++ G ++ K LD + + L+ L V + L P KT
Sbjct: 1071 TVVYSIVSGNEGGVFTVNKSTGIIYTNKSLDYENVTSYVLRVQADSLTVILANLRAPSKT 1130
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
A+V I + D ND+ P F Y + E+ +VL+++ATD D G + Y+L
Sbjct: 1131 NTAKVFINVQDENDHPPVFSRQVYIGGVTEDTKTFTTVLKIVATDVDTGNYSKMAYRLII 1190
Query: 348 P-----KGAFSIDPRSG 359
P + +F I+P +G
Sbjct: 1191 PPTTEGQDSFVIEPYTG 1207
Score = 61.7 bits (143), Expect = 2e-07
Identities = 154/676 (22%), Positives = 263/676 (38%), Gaps = 83/676 (12%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQAR-VEIELLDLNDNLPEFEVDFYNISIVENL 319
LD + T V+Q+Q + N + T V I + D NDN P F+ Y +S+ E
Sbjct: 108 LDRDPPSSITTIVVQIQCT--NELVGTVILHEVRIVVRDRNDNTPRFQQPRYYVSVNELT 165
Query: 320 PNGFSVLQVM-----ATDKDQGENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREA 373
P G ++ ATD D G NG+ Y + +P DP S TVR L
Sbjct: 166 PVGTTIFTGFSGNNGATDIDDGPNGQIEYAIQYNPN-----DPMSN-RTVRIAGTLSGNI 219
Query: 374 HSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIE 433
+ R+ Y + T ++ ++ N ++ Y + T T ++
Sbjct: 220 VLAERLN-YEERTRYLII----------------VQAN---DRAPYPGTRRTATTTLTLD 259
Query: 434 YYDEQLMSFVNVEVTLL-DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL--- 489
D + + + L+ + D NPV + E + + V ++A+D D
Sbjct: 260 VLDGDDLGPMFLPCVLVNNTQDCNPVTYRVAIPELTDPNKLNPLNVTPPIRAIDQDRNIQ 319
Query: 490 --GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANP 545
+LY + + T F +N +T + + +S E R +L ++A +P
Sbjct: 320 PPSDRPGILYFILVGTPSTYPEFFTLNRSTAELRLLKSVDRELYQRFSLVIKAEQDNGHP 379
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV-------GQIRV- 597
L + ++ + N+ P F + Y +V + +GT++ + +
Sbjct: 380 LPAYSKLEIEILD-----ENNQ--APYFQQSSYRGFVSESSSVGTTISASANLTAPLAII 432
Query: 598 ---NDAFEQNDVSYDL-LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN 653
ND E D + L+ Y + +T++ + R + Y VA +
Sbjct: 433 ALDNDIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLKPVDREIQTNYTLTLVA-TDG 491
Query: 654 ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
S + V+D ND + ++S IF G + Q+ + +
Sbjct: 492 VQQSRPVTVDILVIDANDNTPTFAQVSYSVEIF--TNMLPGETVLQLMAQDADA---GLN 546
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
G + + I D D I G I + Y +TV A N
Sbjct: 547 GLITYAIL-AGDHGDFIINNRTGRITLAPGVMLTVGRSYALTVRAADNAPDTERRSSI-T 604
Query: 774 TIYIE---DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
T+YIE N +PP F TY I E +IG I ++ ++ATD + + T
Sbjct: 605 TVYIEVLPPNNQSPPRFPLQTYNLEISEAMRIGA-ILLN--LQATDRELDPITYRIET-- 659
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDEND 888
G+ +E+F++ G++ + LDRE Y+L + A D GG+S+ A + I+I D ND
Sbjct: 660 GDPQEVFNLSRTIGLL-LLAKPLDRETIDQYRLIVTASDGHPGGIST-ATVSIVITDVND 717
Query: 889 NKPEFN-QIEENSKVR 903
N P F+ + N VR
Sbjct: 718 NDPTFDLTLPRNLTVR 733
Score = 58.0 bits (134), Expect = 2e-06
Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
P I A+D D+ + ++ +F++ + + FL +D E ++
Sbjct: 428 PLAIIALDNDIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLKPVDREIQTNYTLTLV 487
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
Q + P+ V+I ++D NDN P F Y++ I N+ G +VLQ+MA D D
Sbjct: 488 ATDGVQQSRPVT-----VDILVIDANDNTPTFAQVSYSVEIFTNMLPGETVLQLMAQDAD 542
Query: 335 QGENGEFTYQ-LDDPKGAFSIDPRSGWLTV 363
G NG TY L G F I+ R+G +T+
Sbjct: 543 AGLNGLITYAILAGDHGDFIINNRTGRITL 572
Score = 58.0 bits (134), Expect = 2e-06
Identities = 106/447 (23%), Positives = 179/447 (40%), Gaps = 52/447 (11%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
++ + L + A DG + ++V + V D ND+ P F + Y+ + + ++ A
Sbjct: 479 QTNYTLTLVATDGVQQSRPVTVDILVIDANDNTPTFAQVSYSVEIFTNMLPGETVLQLMA 538
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG-XX 1128
DAD G N +TY I D F I+ TG +++ + Y LTV A DN
Sbjct: 539 QDADAGLNGLITYAILAGDHG-DFIINNRTGRITLAPGVMLTVGRSYALTVRAADNAPDT 597
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
N+ SP + L+ + E E ++++ +AT E
Sbjct: 598 ERRSSITTVYIEVLPPNNQSPPRFP----LQTYNLEISEAM--RIGAILL--NLQATDRE 649
Query: 1189 NAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQQNL------GLPSLSSTAILM 1239
PI + + + GL+L + P + +Q L G P STA +
Sbjct: 650 LDPITYRIETGDPQEVFNLSRTIGLLLLAKPLDRETIDQYRLIVTASDGHPGGISTATVS 709
Query: 1240 VTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEND 1299
+ + DV D D + + R + EE N V V + N ++RY +L+
Sbjct: 710 IVITDVNDNDPTFD--LTLPRNLTVR-EEEANVFVGQVRATDPDGGLNGQVRYRLLS--- 763
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
F I+ G+++ DRE + Y++IV A D
Sbjct: 764 --FASLFSIN-STGSIFTAVPLDRETRSRYDLIVE-----------------ASDGAVDP 803
Query: 1360 TKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA-IPTTAPFGYQVMQLKGAIGHHPTASRTV 1418
+ + ++V + D+NDNSP F ++P+ T +P P G +++L A+ ++ T
Sbjct: 804 RRTTITLLVEVLDINDNSPVF---SQPVYTVNVPENTPAGSIILRLT-AVDADLVSNVTY 859
Query: 1419 RADTD-ELVFFERLSLNGLTSP-QATD 1443
R T+ L F L G+ S QA D
Sbjct: 860 RIKTEAALQLFAVNRLTGVISVLQALD 886
Score = 50.0 bits (114), Expect = 5e-04
Identities = 86/344 (25%), Positives = 142/344 (41%), Gaps = 45/344 (13%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE--KAFIFLIAPIG--------- 125
+ AY + + I D N+ P F + Y V E + G A L AP+
Sbjct: 380 LPAYSKLEIEILDENNQAPYFQQSSYRGFVSESSSVGTTISASANLTAPLAIIALDNDIE 439
Query: 126 ----PSLTIPL---TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
P L I L T +T R KP +Y++ DG ++ S
Sbjct: 440 ETKDPQLKITLNEYTSIFTITTSGITRFLTLLKPVDREIQTNYTLTLVATDG---VQQS- 495
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYEL 235
+PV + +L DA D ++ I +L E + A D D G+ + Y +
Sbjct: 496 RPVTV--DILVIDANDNTPTFAQVSYSVEIFTNMLPGETVLQLMAQDADAGLNGLITYAI 553
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP---LKTAQARV 292
++G D F +++ G + L + L ++ L V+A+ N P +++ V
Sbjct: 554 LAG-DHGDFIINNRTGRITLAPGVMLTV-----GRSYALTVRAAD-NAPDTERRSSITTV 606
Query: 293 EIELLDLNDNLP-EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPK 349
IE+L N+ P F + YN+ I E + G +L + ATD+ E TY+++ DP+
Sbjct: 607 YIEVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDR---ELDPITYRIETGDPQ 663
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
F++ G L + LDRE R+ V A + +P + T
Sbjct: 664 EVFNLSRTIGLLLLAKP--LDRETIDQYRLIVTASDGHPGGIST 705
Score = 49.2 bits (112), Expect = 9e-04
Identities = 63/263 (23%), Positives = 110/263 (41%), Gaps = 20/263 (7%)
Query: 82 SVTVYIEDVNDNVPIF-LDTPYHVTVDELTPTGEKAFIFL--IAPIGPSLTIPLTVPRGL 138
+V++ I DVNDN P F L P ++TV E E+A +F+ + P + V L
Sbjct: 707 TVSIVITDVNDNDPTFDLTLPRNLTVRE-----EEANVFVGQVRATDPDGGLNGQVRYRL 761
Query: 139 TIFKDIRAFDRDK------PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
F + + + P + Y ++ DG A++ + LL +VLD +
Sbjct: 762 LSFASLFSINSTGSIFTAVPLDRETRSRYDLIVEASDG--AVDPRRTTITLLVEVLDIND 819
Query: 193 GDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
F Q V + + A+D DL T R + + +LF+++ + G
Sbjct: 820 NSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVSNVTYRIKTEAA--LQLFAVNRLTG 877
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ + + LD ++ +T+ +V+A L A V + + D+ND P F Y
Sbjct: 878 VISVLQALDFESLA-AGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDFSPVFRQALY 936
Query: 312 NISIVENLPNGFSVLQVMATDKD 334
+ N G + V+A D+D
Sbjct: 937 KGLVAPNAEKGTVITTVLAEDQD 959
Score = 46.0 bits (104), Expect = 0.008
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 30/201 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P G+ I++L A+D D L + Y +E AL++ F +N G
Sbjct: 833 VPENTPAGSIILRLTAVDAD--LVSNVTYRIKTEA----------ALQL---FAVNRLTG 877
Query: 1000 HVIVARSLPPE------SEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ V ++L E S + + ALD G + +V V + D+ND PVF++ Y
Sbjct: 878 VISVLQALDFESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDFSPVFRQALYK 937
Query: 1052 FNVEEAQYTRRVLGKVDATDAD-FGQNANLTYF-----IQPSDTDLPFEISPLTGVLSVN 1105
V V+ V A D D G A+ + + P + F++ TG++
Sbjct: 938 GLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRVDQELSPYSGSI-FDVETDTGLVITK 996
Query: 1106 GELDRETEDKYILTVVARDNG 1126
L+ + + L V+A D+G
Sbjct: 997 VNLNEQPTTVFKLVVMAYDDG 1017
Score = 43.2 bits (97), Expect = 0.056
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDT 1089
V + V+D NDH PVF + Y V E T + K+ ATD D G + + Y I P T
Sbjct: 1135 VFINVQDENDHPPVFSRQVYIGGVTEDTKTFTTVLKIVATDVDTGNYSKMAYRLIIPPTT 1194
Query: 1090 D--LPFEISPLTGVLSVNGELDRETEDKYI-LTVVARDN 1125
+ F I P TGV+ + + R Y VVA D+
Sbjct: 1195 EGQDSFVIEPYTGVIK-SAIMFRNMRRSYFKFQVVATDD 1232
Score = 39.5 bits (88), Expect = 0.69
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL-----GKVDATDADFGQNANLTYFIQ 1085
VR+ V+D ND+ P F++ Y +V E + G ATD D G N + Y IQ
Sbjct: 138 VRIVVRDRNDNTPRFQQPRYYVSVNELTPVGTTIFTGFSGNNGATDIDDGPNGQIEYAIQ 197
Query: 1086 PSDTD-LPFEISPLTGVLSVN----GELDRETEDKYILTVVARD 1124
+ D + + G LS N L+ E +Y++ V A D
Sbjct: 198 YNPNDPMSNRTVRIAGTLSGNIVLAERLNYEERTRYLIIVQAND 241
Score = 39.1 bits (87), Expect = 0.92
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 740 TQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T + LDR+ + + V + ++ +++V I + D NDN P F+ Y + E
Sbjct: 104 TGRVLDRDPPSSITTIVVQIQCTNELVGTVILHEVRIVVRDRNDNTPRFQQPRYYVSVNE 163
Query: 799 NSKIGTEI--KMDNIIKATDADEGTNALFMYTL 829
+ +GT I ATD D+G N Y +
Sbjct: 164 LTPVGTTIFTGFSGNNGATDIDDGPNGQIEYAI 196
Score = 37.5 bits (83), Expect = 2.8
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF 117
V + + D NDN P F Y+V+V+ELTP G F
Sbjct: 138 VRIVVRDRNDNTPRFQQPRYYVSVNELTPVGTTIF 172
Score = 35.9 bits (79), Expect = 8.6
Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 13/117 (11%)
Query: 217 PIHAIDQDLGVGAT-----LRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQ 268
PI AIDQD + + Y ++ G + F+L+ L L K +D +
Sbjct: 308 PIRAIDQDRNIQPPSDRPGILYFILVGTPSTYPEFFTLNRSTAELRLLKSVDRELYQR-- 365
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
F L ++A Q N A +++EIE+LD N+ P F+ Y + E+ G ++
Sbjct: 366 ---FSLVIKAEQDNGHPLPAYSKLEIEILDENNQAPYFQQSSYRGFVSESSSVGTTI 419
>UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000002131 - Anopheles gambiae
str. PEST
Length = 603
Score = 124 bits (300), Expect = 1e-26
Identities = 148/487 (30%), Positives = 221/487 (45%), Gaps = 53/487 (10%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN PVF +YE S+ + T + ++K D D G+N V ++ +
Sbjct: 1 DINDNAPVF-NREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVGGNE---GGE 56
Query: 511 FKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F++NP TG + +V L+ + L V A DQ NP R+ S A V I V + T N P
Sbjct: 57 FRVNPETGMLYTAVPLDAELKAFYTLTVSAIDQ-GNPGTRKQSSAKVKINV-QDTNDNDP 114
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVPFAVEERS 626
F A +V N GTSV ++ R D E +SY + + + VPF ++ S
Sbjct: 115 I---FETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLND--VPFDIDHFS 169
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV----DVNDERGVLLK---- 678
G + L Y ++ + L + +V DVND R +
Sbjct: 170 GTVRT-SKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCL 228
Query: 679 ---GAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
++PI + SA G + + S + +G N+ VT I++
Sbjct: 229 GRIPRYTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNL-------DSVTGIISVGC 281
Query: 735 D-GTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
D + LDRE++D Y + + + + K S + I +TI DENDN P FE +
Sbjct: 282 DLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLTIL--DENDNVPKFEKSLA 339
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ EN+ GT I +KATDAD G NA Y+L + K+ F VD TGV+ +
Sbjct: 340 SFRVTENAINGTIIFR---VKATDADLGQNAKITYSLVTDTKD-FRVDPETGVLTVVA-P 394
Query: 853 LDREKKIMYKLSLVARDTGG------LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
LDRE++ +Y+L + A D GG L S+A + + + D NDN PEF ++ VRI R
Sbjct: 395 LDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEF--AVQDLTVRI-R 451
Query: 907 ETKLNGT 913
E GT
Sbjct: 452 EDVPRGT 458
Score = 123 bits (296), Expect = 4e-26
Identities = 126/474 (26%), Positives = 218/474 (45%), Gaps = 43/474 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V++ + D NDN+P+F +NL + + N GT + KV A D DLG+N + Y +
Sbjct: 98 SSAKVKINVQDTNDNDPIFETANLTIY-VDENEPAGTSVTKVTARDKDLGENAYISYSIA 156
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEG---RHALFVEASDQPANPSERRYSLAVVTI 557
+++ PF I+ +GTV ++ E + L V ASD P R+ + +V I
Sbjct: 157 NLNDV----PFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGL-PYRRQTEMQLV-I 210
Query: 558 EVTRGTKGNKPDIP--DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++ R N+P D +G + IGT + + D + V+Y LL G+E
Sbjct: 211 KL-RDVNDNRPQFERIDCLGR-----IPRYTPIGTEIFTLSALDFDYGSVVTYRLLSGFE 264
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-------TNATVHVVD 668
+G F ++ +G+I+V DL+ Y + N+++ + + + +
Sbjct: 265 DGC-FNLDSVTGIISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLT 323
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ DE + K S F V EN+ I IF + + + + D D
Sbjct: 324 ILDENDNVPKFEKSLASFRVTENAINGTI--IFRVKATDADLGQNAKITYSLVT--DTKD 379
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ---VTIYIEDENDNPP 785
E G + PLDRE+++VY + + A G + +Y V + ++D NDN P
Sbjct: 380 FRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAP 439
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDENT 843
F I E+ GT + ++ A D D GT++ +Y+ G+G+ F +D+ +
Sbjct: 440 EFAVQDLTVRIREDVPRGTVV---TVVSAIDLDSGTSSEIVYSFGENGDGEGSFRIDKQS 496
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK--PEF 893
G ++ LD E++ ++ L + A D G LSSE +I+ + D N+N+ P+F
Sbjct: 497 GTIR-TARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQF 549
Score = 103 bits (247), Expect = 4e-20
Identities = 122/462 (26%), Positives = 200/462 (43%), Gaps = 59/462 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE P T +I+L D D G N ++ E I + F +N G
Sbjct: 18 VPETSPPNTPVIRLKVTDRDEGKNAKVFLE------IVGGNEGGE-------FRVNPETG 64
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN----LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ A L E + + L +SA+D GN + V++ V+D ND+ P+F+
Sbjct: 65 MLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIFETANLTIY 124
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET- 1112
V+E + + KV A D D G+NA ++Y I + D+PF+I +G + + LD E+
Sbjct: 125 VDENEPAGTSVTKVTARDKDLGENAYISYSI-ANLNDVPFDIDHFSGTVRTSKLLDYESM 183
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL--LEWKHPEADE--- 1167
+Y+L V A D G DVNDN P+F D L + P E
Sbjct: 184 RREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPRYTPIGTEIFT 243
Query: 1168 LSNHNFESVMMIPVYK--ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ- 1224
LS +F+ ++ Y+ + E+ +V + + D N +I Y +R+++
Sbjct: 244 LSALDFDYGSVV-TYRLLSGFEDGCFNLDSVTGIISVGCDL--NDLKIIGYLDRERQDEY 300
Query: 1225 ------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
+LG P S + IL +T+ D D V +K + R E I + V+
Sbjct: 301 LLNITVYDLGKPQKSISKILPLTILDENDNVPKFEKSLASFRVTENAINGTIIFRVKATD 360
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+L +N K+ Y ++ + + F +DP G L +V DRE ++ YE+ +RA
Sbjct: 361 ADLG---QNAKITYSLVTDT-----KDFRVDPETGVLTVVAPLDRERQEVYELKIRATDG 412
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ P +Y D V V + D+NDN+P+F
Sbjct: 413 GGDQNTP-ALYS------------DALVRVTVDDINDNAPEF 441
Score = 95.9 bits (228), Expect = 8e-18
Identities = 74/243 (30%), Positives = 112/243 (46%), Gaps = 11/243 (4%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I+++ N +++ L IP PIGT I L+ALD D G + Y S
Sbjct: 209 VIKLRDVNDNRPQFERIDCLGRIPRYTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDG 266
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNIS--VRVFV 1035
L + + +N+ +I + E+ LNI+ D G +IS + + +
Sbjct: 267 CFNLDSVTGIISVGCDLNDLK--IIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLTI 324
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D ND+ P F+K+ +F V E ++ +V ATDAD GQNA +TY + D F +
Sbjct: 325 LDENDNVPKFEKSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLVTDTKD--FRV 382
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNG---XXXXXXXXXXXXXXXXDVNDNSPKFY 1152
P TGVL+V LDRE ++ Y L + A D G D+NDN+P+F
Sbjct: 383 DPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFA 442
Query: 1153 AFD 1155
D
Sbjct: 443 VQD 445
Score = 91.5 bits (217), Expect = 2e-16
Identities = 87/317 (27%), Positives = 139/317 (43%), Gaps = 21/317 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRGLTI 140
V + ++D NDN PIF + VDE P G +G + I ++ +
Sbjct: 102 VKINVQDTNDNDPIFETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLNDV 161
Query: 141 FKDIRAFDRDKPNTPNSDVH-----YSI-VSGNDDG-HFALESSHKPVLLLRKVLDYDAG 193
DI F + D Y + V +D G + ++ + V+ LR V D
Sbjct: 162 PFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVND---N 218
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRKLFSLDSVNGS 252
+F+ + RI + I + D G+ + Y L+SG + F+LDSV G
Sbjct: 219 RPQFERIDCLG--RIPRYTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNLDSVTGI 276
Query: 253 LFLEKEL-DLDAEHNL---QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
+ + +L DL L + + ++L + L P K+ + + +LD NDN+P+FE
Sbjct: 277 ISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFEK 336
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
+ + EN NG + +V ATD D G+N + TY L F +DP +G LTV
Sbjct: 337 SLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLVTDTKDFRVDPETGVLTV--VAP 394
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE +K+ A +
Sbjct: 395 LDRERQEVYELKIRATD 411
Score = 85.4 bits (202), Expect = 1e-14
Identities = 65/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
E G ++T PLD E + Y +TV A + N G + +V I ++D NDN P+FE A
Sbjct: 62 ETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSA-KVKINVQDTNDNDPIFETAN 120
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
++ EN GT + + A D D G NA Y++ FD+D +G V+
Sbjct: 121 LTIYVDENEPAGTSVTK---VTARDKDLGENAYISYSIANLNDVPFDIDHFSGTVR-TSK 176
Query: 852 SLDREK-KIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
LD E + Y L + A D G +E +L+I + D NDN+P+F +I+ RI R
Sbjct: 177 LLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERID--CLGRIPRY 234
Query: 908 TKLNGTAGFTI 918
T + GT FT+
Sbjct: 235 TPI-GTEIFTL 244
Score = 83.0 bits (196), Expect = 6e-14
Identities = 155/598 (25%), Positives = 234/598 (39%), Gaps = 72/598 (12%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVPFAVEERSGVI 629
P F YE V T V +++V D E + L + G EG F V +G++
Sbjct: 7 PVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVGGNEGGEFRVNPETGML 66
Query: 630 TVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATV--HVVDVNDERGVLLKGAHSPIIF 686
L + Y A+ Q N ++A V +V D ND + + +
Sbjct: 67 YTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIF---ETANLTI 123
Query: 687 HVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
+V EN AG ++ ++ T G + + IAN DV DI GT+ T K LD
Sbjct: 124 YVDENEPAGTSVTKV--TARDKDLGENA-YISYSIANLNDVPFDIDHFS-GTVRTSKLLD 179
Query: 746 REK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
E R Y + V A Q+ I + D NDN P FE G I + IGT
Sbjct: 180 YESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPRYTPIGT 239
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLS 864
EI + A D D G+ + L G F++D TG++ +G L+ + KI+ L
Sbjct: 240 EIFT---LSALDFDYGSVVTYRL-LSGFEDGCFNLDSVTGIIS-VGCDLN-DLKIIGYLD 293
Query: 865 LVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK 924
+D E ++ I + KP+ + SK+ TI++ +
Sbjct: 294 RERQD--------EYLLNITVYDLGKPQ----KSISKI-----------LPLTILD---E 327
Query: 925 NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
N ++ F + EN GT I ++ A D D G N +I Y ++
Sbjct: 328 NDNVPKFEKSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLVTDT---------- 377
Query: 985 ALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN------LNDNISVRVFVK 1036
+ F ++ G + V L E + + L I A DGG L + VRV V
Sbjct: 378 -----KDFRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVD 432
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEI 1095
D+ND+ P F + E V+ V A D D G ++ + Y F + D + F I
Sbjct: 433 DINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGENGDGEGSFRI 492
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN--SPKF 1151
+G + LD E + L V A D G DVN+N +P+F
Sbjct: 493 DKQSGTIRTARMLDFEERQVHSLIVKAIDRG-TPSLSSETSVIVEVIDVNENRFAPQF 549
Score = 78.2 bits (184), Expect = 2e-12
Identities = 55/164 (33%), Positives = 78/164 (47%), Gaps = 11/164 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLG A + Y L++ D K F +D G L + LD + + +
Sbjct: 356 VKATDADLGQNAKITYSLVT--DTKDFRVDPETGVLTVVAPLDRERQEVYELKIRATDGG 413
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
Q N P + A V + + D+NDN PEF V + I E++P G V V A D D G
Sbjct: 414 GDQ-NTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGT 472
Query: 338 NGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLD---REAHS 375
+ E Y D +G+F ID +SG T+R +LD R+ HS
Sbjct: 473 SSEIVYSFGENGDGEGSFRIDKQSG--TIRTARMLDFEERQVHS 514
Score = 77.4 bits (182), Expect = 3e-12
Identities = 59/155 (38%), Positives = 81/155 (52%), Gaps = 10/155 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D+D G A + E++ GN+ F ++ G L+ + LDAE L+A + L V A
Sbjct: 35 DRDEGKNAKVFLEIVGGNEGGEFRVNPETGMLYTA--VPLDAE--LKA-FYTLTVSAIDQ 89
Query: 282 NNP--LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP K + A+V+I + D NDN P FE I + EN P G SV +V A DKD GEN
Sbjct: 90 GNPGTRKQSSAKVKINVQDTNDNDPIFETANLTIYVDENEPAGTSVTKVTARDKDLGENA 149
Query: 340 EFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREA 373
+Y + + F ID SG TVR +LD E+
Sbjct: 150 YISYSIANLNDVPFDIDHFSG--TVRTSKLLDYES 182
Score = 62.5 bits (145), Expect = 9e-08
Identities = 53/154 (34%), Positives = 75/154 (48%), Gaps = 17/154 (11%)
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEM 836
D NDN PVF YE + E S T + +K TD DEG NA + G EG E
Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIR---LKVTDRDEGKNAKVFLEIVGGNEGGE- 56
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG----LSSEAELIIMIGDENDNKPE 892
F V+ TG++ + LD E K Y L++ A D G S A++ I + D NDN P
Sbjct: 57 FRVNPETGML-YTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPI 115
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
F E + + I+ + N AG ++ +V ++K
Sbjct: 116 F----ETANLTIYVDE--NEPAGTSVTKVTARDK 143
Score = 60.9 bits (141), Expect = 3e-07
Identities = 56/183 (30%), Positives = 78/183 (42%), Gaps = 29/183 (15%)
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
D+ND+ PVF + Y +V E + ++ TD D G+NA + I + F ++
Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVGGNEGGEFRVN 60
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
P TG+L LD E + Y LTV A D G D NDN P F
Sbjct: 61 PETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIF---- 116
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL 1215
E +N + +Y ++EN P GT+V KV A D D +G N I
Sbjct: 117 -----------ETAN--------LTIY---VDENEPAGTSVTKVTARDKD-LGE-NAYIS 152
Query: 1216 YSL 1218
YS+
Sbjct: 153 YSI 155
Score = 59.7 bits (138), Expect = 6e-07
Identities = 73/286 (25%), Positives = 130/286 (45%), Gaps = 28/286 (9%)
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN-DVSYDLLHGYEEGVPFAVEERS 626
++P F + F V N GT + +++ DA QN ++Y L+ ++ F V+ +
Sbjct: 330 NVPKFEKSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLVTDTKD---FRVDPET 386
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENANLS---IVTNATVHVV--DVNDERGVLLKGAH 681
GV+TVV L R + +Y+ + A + + + ++A V V D+ND A
Sbjct: 387 GVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEF---AV 443
Query: 682 SPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAI-AEDGTI 738
+ ++E+ G + + ++ S GT + + + D I + GTI
Sbjct: 444 QDLTVRIREDVPRGTVVTVVSAIDLDS----GTSSEIVYSFGENGDGEGSFRIDKQSGTI 499
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHATYEGFI 796
T + LD E+R V+ + V A ++G S + V + + D N+N P FE G I
Sbjct: 500 RTARMLDFEERQVHSLIVKA-IDRGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAI 558
Query: 797 MENSKIGTEIKMDNIIKATDAD-EGTNALFMYTL-FGEGKEMFDVD 840
EN G ++ + A DAD G ++ Y++ G+G +F +D
Sbjct: 559 AENKPPGAQVMQ---VLAKDADLPGPDSRVTYSIKGGDGLGIFTID 601
Score = 59.3 bits (137), Expect = 8e-07
Identities = 43/144 (29%), Positives = 73/144 (50%), Gaps = 11/144 (7%)
Query: 218 IHAIDQDLGVGATLRYEL-ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ AID D G + + Y +G+ F +D +G++ + LD + Q ++ + V
Sbjct: 463 VSAIDLDSGTSSEIVYSFGENGDGEGSFRIDKQSGTIRTARMLDFEER---QVHSLI--V 517
Query: 277 QASQLNNPLKTAQARVEIELLDLNDN--LPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+A P +++ V +E++D+N+N P+FE +I EN P G V+QV+A D D
Sbjct: 518 KAIDRGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPGAQVMQVLAKDAD 577
Query: 335 -QGENGEFTYQL--DDPKGAFSID 355
G + TY + D G F+ID
Sbjct: 578 LPGPDSRVTYSIKGGDGLGIFTID 601
Score = 55.6 bits (128), Expect = 1e-05
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 13/165 (7%)
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
D+NDN P F + Y +S+ E P V+++ TD+D+G+N + ++ + G F ++
Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVGGNEGGEFRVN 60
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYA-KETNPSVVGTFADSQRIAKWRRQPLETNAPL 414
P +G L LD E + + V A + NP GT S K Q N P+
Sbjct: 61 PETGML--YTAVPLDAELKAFYTLTVSAIDQGNP---GTRKQSSAKVKINVQDTNDNDPI 115
Query: 415 EKTT--YVFPDK---VGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
+T ++ D+ GT + D+ L + ++ + ND
Sbjct: 116 FETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLND 160
Score = 49.6 bits (113), Expect = 6e-04
Identities = 53/194 (27%), Positives = 81/194 (41%), Gaps = 15/194 (7%)
Query: 412 APLEKTTY-VFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMK 470
APL++ V+ K+ + L S V VT+ D NDN P F +L ++
Sbjct: 393 APLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDL-TVRIR 451
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG 530
+ GTV+ V A+D D G + ++Y N F+I+ +GT+ A E
Sbjct: 452 EDVPRGTVVTVVSAIDLDSGTSSEIVYSF--GENGDGEGSFRIDKQSGTIRTARMLDFEE 509
Query: 531 R--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM--GAPYEFWVGSNV 586
R H+L V+A D+ S+ V I+V P D++ GA + N
Sbjct: 510 RQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFA--PQFEDYVLTGA-----IAENK 562
Query: 587 GIGTSVGQIRVNDA 600
G V Q+ DA
Sbjct: 563 PPGAQVMQVLAKDA 576
Score = 45.2 bits (102), Expect = 0.014
Identities = 47/156 (30%), Positives = 76/156 (48%), Gaps = 19/156 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++P GT + ++A+DLDSG + +I Y F + D + F I+++ G
Sbjct: 450 IREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGE---------NGDG---EGSFRIDKQSG 497
Query: 1000 HVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDH--FPVFKKTWYNFN 1053
+ AR L E L + A+D G +L+ SV V V DVN++ P F+
Sbjct: 498 TIRTARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGA 557
Query: 1054 VEEAQYTRRVLGKVDATDADF-GQNANLTYFIQPSD 1088
+ E + + +V A DAD G ++ +TY I+ D
Sbjct: 558 IAENKPPGAQVMQVLAKDADLPGPDSRVTYSIKGGD 593
Score = 39.5 bits (88), Expect = 0.69
Identities = 19/48 (39%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
+ATD+D+G NA I Y ++ + F +DP +G + VVA L R+ V+
Sbjct: 357 KATDADLGQNAKITYSLVTD-TKDFRVDPETGVLTVVAPLDRERQEVY 403
>UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 18
SCAF15030, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1521
Score = 124 bits (299), Expect = 2e-26
Identities = 161/626 (25%), Positives = 260/626 (41%), Gaps = 77/626 (12%)
Query: 744 LDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE++D Y + + + + S + +V+I D NDN P FE +TYE + EN+
Sbjct: 364 LDREQKDSYELILRVRDGGNPPRSSQALLRVSI--TDVNDNSPQFERSTYEAEMAENAPP 421
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDSLDREKK 858
GT + ++A+D D G N Y +FG E + +DE TG + + +DRE+
Sbjct: 422 GTPVLQ---VRASDRDVGVNGQVEY-VFGAATESVRRLLRLDEATGWLSVL-HRIDREEV 476
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
+ ++ ARD G + +++ + DENDN P +I + ++ + L
Sbjct: 477 AQLRFTVTARDRGQPPRTDRTTVVLAVRDENDNVPVV-EIRKIGRIPVRDGAAL--VPEN 533
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
+++ D DQ EN + T++ D+ L E +
Sbjct: 534 VLVDTPVALVQVSDRDQ-------GENGAVTCTVVG----DVPFTLKPA------GETVL 576
Query: 977 PPSKLSADALE--VKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVR 1032
PP + DA + K+YF+ H E+ + I A+D G +L+ N S+
Sbjct: 577 PPLP-AEDAFDRNKKKYFL------HTSALLDYETTKEYSVTIVAVDSGSPSLSSNSSLM 629
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
V V D+NDH P+F ++ + E + V ATDAD G+NA + + + P+ P
Sbjct: 630 VRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDADSGKNAEIAFSLDPAGNG-P 688
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK-- 1150
F I G + G LDRE ++Y L V+A+D G D NDN+PK
Sbjct: 689 FYIDADNGDIRATGVLDREQRERYELRVIAKDKG-TPSLQGSATVVIQVTDRNDNAPKFA 747
Query: 1151 -----FYAFDELLEWKH------PEADELSNHNFESVMMI------PVYKATIEENAPIG 1193
FY + LL +ADE N + I + +T +E+A G
Sbjct: 748 QEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKG 807
Query: 1194 TTVAKVFANDTDFIGNG-----NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE 1248
N+T I + L +Y+ R + G P ++TA + + V D D
Sbjct: 808 QEEMFSIENNTGTIFSSASFDREKLSIYTF--RVRAVDGGEPRKTATATVSLFVTDENDN 865
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVI 1308
P S Y L + V V ++ N +RY ++ N R F I
Sbjct: 866 APSITSPANES-YTLLPPASSARTVVRTVKAVDSDSGLNADLRYALVGGNP---YRLFEI 921
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIVR 1334
NG + L +R + + ++VR
Sbjct: 922 GHTNGVITLAEPLERRHRGLHRLVVR 947
Score = 104 bits (250), Expect = 2e-20
Identities = 137/495 (27%), Positives = 211/495 (42%), Gaps = 67/495 (13%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V++ D NDN+P F S YE M NA GT + +V+A D D+G NG V Y +
Sbjct: 392 LRVSITDVNDNSPQFERST-YEAEMAENAPPGTPVLQVRASDRDVGVNGQVEYVFGAATE 450
Query: 505 LTITSPFKINPNTGTVSVAE----SPILEGRHALFVEASDQPANPSERRYSLAVV----T 556
++ +++ TG +SV + + R + QP LAV
Sbjct: 451 -SVRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRGQPPRTDRTTVVLAVRDENDN 509
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN---------DV 606
+ V K + + D GA V NV + T V ++V+D + +N DV
Sbjct: 510 VPVVEIRKIGRIPVRD--GAAL---VPENVLVDTPVALVQVSDRDQGENGAVTCTVVGDV 564
Query: 607 SYDLLHGYEEGVP-------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSI 658
+ L E +P F ++ + L Y VA+ + +LS
Sbjct: 565 PFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSVTIVAVDSGSPSLSS 624
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVR 717
++ V VVD+ND + A S + H EN S G + + T+ S +
Sbjct: 625 NSSLMVRVVDINDHPPIF---AQSVVEVHFAENNSPGERVVTVVATDADS---GKNAEIA 678
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
F + + I A++G I LDRE+R+ Y + VIA+ +KG S G V I +
Sbjct: 679 FSLDPAGNGPFYID-ADNGDIRATGVLDREQRERYELRVIAK-DKGTPSLQGSATVVIQV 736
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFG----- 831
D NDN P F + ++ EN + + M + TDADEG NA L ++ G
Sbjct: 737 TDRNDNAPKFAQEIFTFYVKENLLANSPVGM---VTVTDADEGENAELSLFVEIGGPEER 793
Query: 832 ------------EG-KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE 876
+G +EMF ++ NTG + F S DREK +Y + A D G ++
Sbjct: 794 KMVGSTEDEDAEKGQEEMFSIENNTGTI-FSSASFDREKLSIYTFRVRAVDGGEPRKTAT 852
Query: 877 AELIIMIGDENDNKP 891
A + + + DENDN P
Sbjct: 853 ATVSLFVTDENDNAP 867
Score = 85.4 bits (202), Expect = 1e-14
Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 7/160 (4%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ T LD E Y +T++A + G S + + + + D ND+PP+F + E
Sbjct: 594 LHTSALLDYETTKEYSVTIVA-VDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFA 652
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN+ G + + ATDAD G NA ++L G F +D + G ++ G LDRE+
Sbjct: 653 ENNSPGERVVT---VVATDADSGKNAEIAFSLDPAGNGPFYIDADNGDIRATG-VLDREQ 708
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ Y+L ++A+D G L A ++I + D NDN P+F Q
Sbjct: 709 RERYELRVIAKDKGTPSLQGSATVVIQVTDRNDNAPKFAQ 748
Score = 85.0 bits (201), Expect = 1e-14
Identities = 114/485 (23%), Positives = 185/485 (38%), Gaps = 51/485 (10%)
Query: 445 VEVTLLDANDNNPVF-------VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
V + + D NDN PV +P + N V T + V+ D D G+NG V
Sbjct: 499 VVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLVDTPVALVQVSDRDQGENGAV-- 556
Query: 498 DLQRTSNLTITSPFKINPNTGTVSV---AESPILEGRHALFVEASDQPANPSERRYSLAV 554
T + PF + P TV AE + F+ S + + YS+ +
Sbjct: 557 ----TCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSVTI 612
Query: 555 VTIEVTRGTKGNKPDI-----------PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
V ++ + + + P F + E N G V + DA
Sbjct: 613 VAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDADSG 672
Query: 604 NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
+ PF ++ +G I L R R Y+ +A ++ S+ +AT
Sbjct: 673 KNAEIAFSLDPAGNGPFYIDADNGDIRATGVLDREQRERYELRVIA-KDKGTPSLQGSAT 731
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTN--------MSSIYGNGTG 714
V V+ V D K A F+VKEN A + +G + T+ +S G
Sbjct: 732 V-VIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGGP 790
Query: 715 NVRFLIANQQDVTDDIAIAE-------DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
R ++ + +D + E GTIF+ DREK +Y V A + G
Sbjct: 791 EERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRA-VDGGEPRK 849
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
V++++ DENDN P E + + + +KA D+D G NA Y
Sbjct: 850 TATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVV-RTVKAVDSDSGLNADLRY 908
Query: 828 TLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIG 884
L G +F++ GV+ + + L+R + +++L + D+G L + A + I I
Sbjct: 909 ALVGGNPYRLFEIGHTNGVIT-LAEPLERRHRGLHRLVVRVTDSGIPSLCATALVHIFIN 967
Query: 885 DENDN 889
D N
Sbjct: 968 DSLAN 972
Score = 77.4 bits (182), Expect = 3e-12
Identities = 41/122 (33%), Positives = 69/122 (56%), Gaps = 6/122 (4%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
Q +++ L ++ NP +++QA + + + D+NDN P+FE Y + EN P G VLQ
Sbjct: 368 QKDSYELILRVRDGGNPPRSSQALLRVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQ 427
Query: 328 VMATDKDQGENGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
V A+D+D G NG+ Y + + +D +GWL+V ++ +DRE + LR V A
Sbjct: 428 VRASDRDVGVNGQVEYVFGAATESVRRLLRLDEATGWLSVLHR--IDREEVAQLRFTVTA 485
Query: 384 KE 385
++
Sbjct: 486 RD 487
Score = 68.5 bits (160), Expect = 1e-09
Identities = 112/449 (24%), Positives = 186/449 (41%), Gaps = 79/449 (17%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P GT ++++ A D D G+NGQ+ Y F A V+R ++E G +
Sbjct: 417 ENAPPGTPVLQVRASDRDVGVNGQVEYVFG-----------AATESVRRLLRLDEATGWL 465
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNFNVEE 1056
V + E ++ R ++A D G D +V + V+D ND+ PV + + V +
Sbjct: 466 SVLHRIDREEVAQLRFTVTARDRGQPPRTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRD 525
Query: 1057 --AQYTRRVL-----GKVDATDADFGQNANLT--------YFIQPS-DTDLP-------F 1093
A VL V +D D G+N +T + ++P+ +T LP F
Sbjct: 526 GAALVPENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAF 585
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+ + L + LD ET +Y +T+VA D+G D+ND+ P F
Sbjct: 586 DRNKKKYFLHTSALLDYETTKEYSVTIVAVDSGSPSLSSNSSLMVRVV-DINDHPPIFA- 643
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGL 1213
++E E +N E V+ + A +NA I ++ N +I NG
Sbjct: 644 -QSVVEVHFAE----NNSPGERVVTVVATDADSGKNAEIAFSLDPA-GNGPFYIDADNGD 697
Query: 1214 I----LYSLPQRKNQQ------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
I + QR+ + + G PSL +A +++ V D D P F +
Sbjct: 698 IRATGVLDREQRERYELRVIAKDKGTPSLQGSATVVIQVTDRNDNA-----PKFAQEIFT 752
Query: 1264 LEIEENV--NAPVELVSLNLTEHYENFKMRYYIL-----------NENDTDIRR----TF 1306
++EN+ N+PV +V++ + EN ++ ++ + D D + F
Sbjct: 753 FYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKGQEEMF 812
Query: 1307 VIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
I+ GT++ S DRE Y VRA
Sbjct: 813 SIENNTGTIFSSASFDREKLSIYTFRVRA 841
Score = 64.5 bits (150), Expect = 2e-08
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
FL LD E + + ++ V + +P ++ + + + ++D+ND+ P F +
Sbjct: 593 FLHTSALLDYETTKEYSVTIVAVDSG---SPSLSSNSSLMVRVVDINDHPPIFAQSVVEV 649
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDRE 372
EN G V+ V+ATD D G+N E + LD G F ID +G +R VLDRE
Sbjct: 650 HFAENNSPGERVVTVVATDADSGKNAEIAFSLDPAGNGPFYIDADNG--DIRATGVLDRE 707
Query: 373 AHSSLRMKVYAKET-NPSVVGT 393
++V AK+ PS+ G+
Sbjct: 708 QRERYELRVIAKDKGTPSLQGS 729
Score = 58.4 bits (135), Expect = 1e-06
Identities = 93/365 (25%), Positives = 145/365 (39%), Gaps = 44/365 (12%)
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK----KIM 860
++K+ N+ GT + + G E F +D TG + +DREK +++
Sbjct: 171 DVKIGNVAADLGLTAGTGSGDVTFALESGSEYFKIDNVTGELTTGPRRIDREKLPQCQMI 230
Query: 861 YK-----LSLVARDTGGLSSEAELI---IMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
+ L G L S +L ++I D NDN P F E + R+T +
Sbjct: 231 FDENECFLDFEVSVIGPLQSWVDLFEGRVVITDINDNTPSFPSPEPFTCFP-PRQTGILA 289
Query: 913 TAGFTIIEVKPKNKFAL-DVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
T + N F + ++QL P + G+ I ++ AL G NG+ N
Sbjct: 290 EMALTDM-----NSFRMVQLEQLQP-----DAQREGSPITRVEALGDRRGRNGE-----N 334
Query: 972 SEVYIPPSKLS-ADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LN 1026
KL AD + E+ +IV +L E + + L + DGGN +
Sbjct: 335 GGARSTVFKLQVADIPD-------GEKQPQLIVKGTLDREQKDSYELILRVRDGGNPPRS 387
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+RV + DVND+ P F+++ Y + E + +V A+D D G N + Y
Sbjct: 388 SQALLRVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQVRASDRDVGVNGQVEYVFGA 447
Query: 1087 SDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ + + TG LSV +DRE + TV ARD G D
Sbjct: 448 ATESVRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRG-QPPRTDRTTVVLAVRDE 506
Query: 1145 NDNSP 1149
NDN P
Sbjct: 507 NDNVP 511
Score = 55.6 bits (128), Expect = 1e-05
Identities = 38/123 (30%), Positives = 55/123 (44%), Gaps = 6/123 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G A + + L + F +D+ NG + LD + Q + L+V A
Sbjct: 666 ATDADSGKNAEIAFSLDPAGNGP-FYIDADNGDIRATGVLDRE-----QRERYELRVIAK 719
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P A V I++ D NDN P+F + + + ENL V V TD D+GEN
Sbjct: 720 DKGTPSLQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENA 779
Query: 340 EFT 342
E +
Sbjct: 780 ELS 782
Score = 55.2 bits (127), Expect = 1e-05
Identities = 86/372 (23%), Positives = 140/372 (37%), Gaps = 38/372 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S ++ V ++D ND+ P+F S + E N G + V A D D G+N + +
Sbjct: 622 LSSNSSLMVRVVDINDHPPIFAQS-VVEVHFAENNSPGERVVTVVATDADSGKNAEIAFS 680
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
L N PF I+ + G + E R+ L V A D+ PS + A V
Sbjct: 681 LDPAGN----GPFYIDADNGDIRATGVLDREQRERYELRVIAKDK-GTPSLQ--GSATVV 733
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL---LHG 613
I+VT + P F + F+V N+ + VG + V DA E + L + G
Sbjct: 734 IQVT----DRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGG 789
Query: 614 YEE----------------GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS 657
EE F++E +G I R +Y F A+
Sbjct: 790 PEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDGGEPRK 849
Query: 658 IVT-NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
T ++ V D ND + A+ +SA + + + S ++
Sbjct: 850 TATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVRTVKAVDSDS---GLNADL 906
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
R+ + +G I +PL+R R ++R+ V+ + G+ S V I+
Sbjct: 907 RYALVGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRL-VVRVTDSGIPSLCATALVHIF 965
Query: 777 IEDENDNPPVFE 788
I D N + E
Sbjct: 966 INDSLANASLVE 977
Score = 52.4 bits (120), Expect = 9e-05
Identities = 59/228 (25%), Positives = 96/228 (42%), Gaps = 12/228 (5%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L G+A +I+V +N A Q F + EN+ + + + D D G N ++
Sbjct: 726 LQGSAT-VVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLF 784
Query: 970 FN----SEVYIPPSKLSADALE-VKRYFVINERHGHVIVARSLPPE--SEFRLNISALDG 1022
E + S DA + + F I G + + S E S + + A+DG
Sbjct: 785 VEIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDG 844
Query: 1023 GNLNDNIS--VRVFVKDVNDHFP-VFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNA 1078
G + V +FV D ND+ P + ++ + A R V+ V A D+D G NA
Sbjct: 845 GEPRKTATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVRTVKAVDSDSGLNA 904
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+L Y + + FEI GV+++ L+R + L V D+G
Sbjct: 905 DLRYALVGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRLVVRVTDSG 952
Score = 45.2 bits (102), Expect = 0.014
Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 24/153 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G PSLSS + LMV V D+ D P+F E+ EN N+P E V + ++
Sbjct: 618 GSPSLSSNSSLMVRVVDINDH-----PPIFAQSVVEVHFAEN-NSPGERVVTVVATDADS 671
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
K + +I F +DP + + + + +++ T V+ R +R++Y +
Sbjct: 672 GK---------NAEI--AFSLDPAGNGPFYIDADNGDIRAT-GVLDREQRERYELRV--- 716
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+A+D + VV+++ D NDN+PKF
Sbjct: 717 ---IAKDKGTPSLQGSATVVIQVTDRNDNAPKF 746
Score = 44.0 bits (99), Expect = 0.032
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 15/135 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+D+GV + Y + + R+L LD G L + +D + L+
Sbjct: 428 VRASDRDVGVNGQVEYVFGAATESVRRLLRLDEATGWLSVLHRIDREEVAQLR-----FT 482
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN--------ISIVENLPNGFSVLQ 327
V A P +T + V + + D NDN+P E+ + EN+ V
Sbjct: 483 VTARDRGQPPRTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLVDTPVAL 542
Query: 328 VMATDKDQGENGEFT 342
V +D+DQGENG T
Sbjct: 543 VQVSDRDQGENGAVT 557
Score = 44.0 bits (99), Expect = 0.032
Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 13/172 (7%)
Query: 227 VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
VG+T + G + ++FS+++ G++F D + + + + +V+A P K
Sbjct: 796 VGSTEDEDAEKGQE-EMFSIENNTGTIFSSASFDRE-----KLSIYTFRVRAVDGGEPRK 849
Query: 287 TAQARVEIELLDLNDNLPEFEVDF-YNISIVENLPNGFSVLQ-VMATDKDQGENGEFTYQ 344
TA A V + + D NDN P + +++ + +V++ V A D D G N + Y
Sbjct: 850 TATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVRTVKAVDSDSGLNADLRYA 909
Query: 345 L--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
L +P F I +G +T+ L+R R+ V ++ PS+ T
Sbjct: 910 LVGGNPYRLFEIGHTNGVITLAEP--LERRHRGLHRLVVRVTDSGIPSLCAT 959
Score = 41.1 bits (92), Expect = 0.23
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D G+ A LRY L+ GN +LF + NG + L + L+ + + V++V
Sbjct: 893 VKAVDSDSGLNADLRYALVGGNPYRLFEIGHTNGVITLAEPLE---RRHRGLHRLVVRVT 949
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
S + + TA + I N +L E ++
Sbjct: 950 DSGIPSLCATALVHIFINDSLANASLVEAQI 980
Score = 37.1 bits (82), Expect = 3.7
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L V G LDRE +D Y L + RD G DVNDNSP+F
Sbjct: 358 LIVKGTLDREQKDSYELILRVRDGGNPPRSSQALLRVSIT-DVNDNSPQF 406
>UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumor
suppressor homolog precursor; n=3; Diptera|Rep: Putative
fat-like cadherin-related tumor suppressor homolog
precursor - Drosophila melanogaster (Fruit fly)
Length = 4705
Score = 124 bits (299), Expect = 2e-26
Identities = 128/510 (25%), Positives = 224/510 (43%), Gaps = 50/510 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+T+LD NDN PV + L F + +A++GTV+ + A D D G N V Y L
Sbjct: 862 ITILDVNDNRPV-IQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALS-----V 915
Query: 507 ITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
S F +N TG + + P+ + +AL + A D +P +L V ++
Sbjct: 916 ECSDFTVNATTGCLRL-NKPLDREKQDNYALHITAKDG-GSPVLSSEALVYVLVDDVND- 972
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFA 621
+ P F Y F V ++ GT + I D ++ + L ++ F
Sbjct: 973 -----NAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFR 1027
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGA 680
+++ +G I L N+ +++ A+ + +L+ + + ++DVN+ R
Sbjct: 1028 IDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENR---FAPE 1084
Query: 681 HSPIIFH--VKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
++ VKEN G + + +M ++ N + + I D A+ + G+
Sbjct: 1085 FDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNS--KITYSITGG-DGLGIFAVNDQGS 1141
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
I + LD E ++ Y +T+ A+ + ++ + +V I +E+ENDN P+ + Y +
Sbjct: 1142 ITSLSQLDAETKNFYWLTLCAQ-DCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVT 1200
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDRE 856
E S EI +KA D D Y + G F++D TGV+K LDRE
Sbjct: 1201 EASVENVEIIT---LKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRE 1257
Query: 857 KKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ------IEENSKVR----- 903
+ + L + D G LSS + +++ + D NDN PEF+Q + ++ V
Sbjct: 1258 NQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQ 1317
Query: 904 ---IHRETKLNGTAGFTIIEVKPKNKFALD 930
I ++ NG ++I K KNKF +D
Sbjct: 1318 VHAIDSDSGENGRITYSIKSGKGKNKFRID 1347
Score = 122 bits (295), Expect = 6e-26
Identities = 117/468 (25%), Positives = 212/468 (45%), Gaps = 33/468 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ +V + + D NDN P F + Y S+ N++ + KV A D D G NG + Y L+
Sbjct: 2858 AYADVLIDVRDENDNYPKF-DNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLE 2916
Query: 501 RTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ I + F I+ +G +++ S ++ + V A+D N + + VTI+
Sbjct: 2917 SDTE-NIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAAD---NGHPKHDAKVPVTIK 2972
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS-VGQIRVNDAFEQNDVSYDLLHGYEEG 617
+ + P F V N GT + + ++ E+ ++ + ++ G ++
Sbjct: 2973 IV----DYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSG-DKQ 3027
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F + +SG + + L R Y+ +A + + N + V D+ND L
Sbjct: 3028 AQFQIG-KSGELFIAKPLDREQLMFYNLSIIAT--DGKFTAKANVEIDVKDINDNTPYCL 3084
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-EDG 736
K +H+ N + +IG + +I + +RF ++ + DD +I E G
Sbjct: 3085 KPR-----YHISTNES-ISIGTTL-VEVKAIDFDFQSKLRFYLSGKG--ADDFSIGKESG 3135
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ LDRE Y++ + K ++ I + D NDN P+F A Y +
Sbjct: 3136 ILKVASALDRETTPKYKLVAHVQDGKDFTQEC-FSEIIITVNDINDNMPIFSMAQYRVSV 3194
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
E++++ T I + A D D G N Y+L GE + F + ++TG+++ + SLDRE
Sbjct: 3195 PEDAQLNTLITK---VHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIR-LHKSLDRE 3250
Query: 857 KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ L++ A D G L S A + + I D NDN PEF+ + + K+
Sbjct: 3251 TISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKI 3298
Score = 121 bits (291), Expect = 2e-25
Identities = 163/638 (25%), Positives = 275/638 (43%), Gaps = 70/638 (10%)
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDV 606
RR++ V I++ K +IP F YE + I V +++V+D +N +
Sbjct: 376 RRFAYKSVPIQI----KPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNAL 431
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVH 665
Y + G EG F + SG++ L + Y A+ Q N ++A V
Sbjct: 432 VYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVK 491
Query: 666 --VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V D+ND + + + I + + N AG+ + ++ + S + + IAN
Sbjct: 492 ISVQDMNDNDPIF-ENVNKVISIN-ENNLAGSFVVKLTAKDRDS---GENSYISYSIANL 546
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTIYIEDEND 782
V +I G + T LD E +I + G+ +++I ++D ND
Sbjct: 547 NAVPFEIDHFS-GIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDIND 605
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVD 840
N P FE G + +++ +GTE+ + A D D G + Y L +G E F++D
Sbjct: 606 NRPQFERVNCYGKVTKSAPMGTEVF---VTSAIDFDAGD--IISYRL-SDGNEDGCFNLD 659
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI-------GDENDNKPEF 893
+G + S D +K + L T G +LII + G ++ F
Sbjct: 660 PTSGSLSI---SCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGF 716
Query: 894 NQIE--ENSKVRIHRET---------KLNGTAGFTIIEVKPKNKFALDVDQLGPLFL--- 939
E E R ET K + F+ + + P +++ +V + P F+
Sbjct: 717 GSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTP-SRYGQNVHR--PEFVNFP 773
Query: 940 ----IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
I E++ +G T+ + A D D G NG++ + + Y ++ D E++ +I
Sbjct: 774 QELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQ---II- 829
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFN 1053
G++ R ++E+ LNI+ D GN + S + + + DVND+ PV +KT F
Sbjct: 830 ---GYLDRER----QNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFR 882
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ E+ V+ + ATDAD G NA +TY + +D F ++ TG L +N LDRE +
Sbjct: 883 LTESARIGTVVHCLHATDADSGINAQVTYALSVECSD--FTVNATTGCLRLNKPLDREKQ 940
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D Y L + A+D G DVNDN+P F
Sbjct: 941 DNYALHITAKDGG-SPVLSSEALVYVLVDDVNDNAPVF 977
Score = 116 bits (279), Expect = 5e-24
Identities = 193/849 (22%), Positives = 345/849 (40%), Gaps = 75/849 (8%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPR 136
AY SV + I+ + N+PIF Y V++ E P ++ +G + + L +
Sbjct: 379 AYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVG 438
Query: 137 G-----LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFAL--ESSHKPVLLLRKVL 188
G I D K Y++ VS D + +SS K + ++ +
Sbjct: 439 GNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMN 498
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
D D + VI + + F + A D+D G + + Y + + N F +D
Sbjct: 499 DNDPIFENVNKVISINENNLAGS--FVVKLTAKDRDSGENSYISYSIANLNAVP-FEIDH 555
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT-AQARVEIELLDLNDNLPEFE 307
+G + LD + + L ++AS P + + ++ I + D+NDN P+FE
Sbjct: 556 FSGIVKTTSLLDFET----MKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFE 611
Query: 308 -VDFYNISIVENLPNGFSVLQVMATDKDQGE---------NGEFTYQLDDPKGAFSI--D 355
V+ Y + ++ P G V A D D G+ N + + LD G+ SI D
Sbjct: 612 RVNCYG-KVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCD 670
Query: 356 PRSGWLTVRNQTVLDREA-HSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPL 414
+ LT R V + H S + + + G + + + L
Sbjct: 671 LKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRL 730
Query: 415 EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK 474
+T + + N++ + S +++ + N + P FV + E S+ + +
Sbjct: 731 AETLSL------AEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFV-NFPQELSINESVQ 783
Query: 475 VGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRH 532
+G + ++A D DLG NG +++ + S+ S F+I+P+ G + + + +
Sbjct: 784 LGETVAWIEAKDRDLGYNGKLVFAI---SDGDYDSVFRIDPDRGELQIIGYLDRERQNEY 840
Query: 533 ALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
L + D NP++ + +TI N+P I + F + + IGT V
Sbjct: 841 VLNITVYDL-GNPTKSTSKMLPITI---LDVNDNRPVIQKTLAT---FRLTESARIGTVV 893
Query: 593 GQIRVNDAFEQNDVSYDLLHGYE-EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
+ DA + ++ + + E F V +G + + L R + Y A +
Sbjct: 894 HCLHATDA--DSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITA-K 950
Query: 652 ENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
+ + + + A V+V+ DVND V G IF V+E+ + + I
Sbjct: 951 DGGSPVLSSEALVYVLVDDVNDNAPVF--GVQE-YIFKVREDLPRGTVLAVIEAVDEDIG 1007
Query: 710 GNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
N ++F + + + I G I TQ LD E + V+ + +++ + G S
Sbjct: 1008 PN--AEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNL-IVSAIDGGDPSLT 1064
Query: 769 GIYQVTIYIEDENDN--PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTNALF 825
+ I I D N+N P F+ YEG + EN GT + + A D D N+
Sbjct: 1065 SDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMN---VTARDMDTVDLNSKI 1121
Query: 826 MYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIM 882
Y++ G+G +F V++ + LD E K Y L+L A+D LS+ E+ I
Sbjct: 1122 TYSITGGDGLGIFAVNDQGSITSL--SQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQ 1179
Query: 883 IGDENDNKP 891
+ +ENDN P
Sbjct: 1180 VENENDNIP 1188
Score = 112 bits (270), Expect = 6e-23
Identities = 117/486 (24%), Positives = 212/486 (43%), Gaps = 44/486 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
I D +F N+ V ++D NDN P F ++Y ++ N + +VI ++ A D D +
Sbjct: 1476 ISVTDGTFTAFTNLLVQVIDINDNPPQFA-KDVYHVNISENIEEESVIMQLHATDRD--E 1532
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERR 549
+ + Y L T + + + F+I+ +G V V + E +H L V DQ A P +R
Sbjct: 1533 DKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGA-PGKRN 1591
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVS 607
Y+ +V + + P+F + V + IG+ + ++R D+ ++
Sbjct: 1592 YAKIIVNVH------DHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQ 1645
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y ++ G G F ++ G+IT+ +L+ Y + A+ + N + + VH++
Sbjct: 1646 YSIITG-NVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAV-DLGNPPLSSQIPVHII 1703
Query: 668 DVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
E K + I + EN G + Q+ + SSI+ N +I+ ++
Sbjct: 1704 VTMSENDPP-KFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFN-------IISG--NI 1753
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ I G I +D E V+ +TV + + + + I+I D NDN P
Sbjct: 1754 NESFRINPSTGVIVINGNIDYESIKVFNLTVKGT---NMAAESSCQNIIIHILDANDNIP 1810
Query: 786 VFEHATYEGFIMENSKIGTEI------KMDNI-IKATDADEGTNALFMYTLFGE-GKEMF 837
F Y G + E++ IG+ + D++ ++ DAD G N + Y + + K F
Sbjct: 1811 YFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFF 1870
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG----GLSSEAELIIMIGDENDNKPEF 893
+D TG ++ + LD E Y + D G ++ A + I + + ND P F
Sbjct: 1871 KIDSTTGAIELL-RQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVF 1929
Query: 894 NQIEEN 899
N+ E N
Sbjct: 1930 NERELN 1935
Score = 108 bits (259), Expect = 1e-21
Identities = 127/514 (24%), Positives = 217/514 (42%), Gaps = 44/514 (8%)
Query: 421 FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
F DK T NI D ++ ++++LL N +P+F S YE + N G I
Sbjct: 2530 FTDKSSTVL-NISVSDGVHTAYARLKISLLPENVYSPLFDQST-YEAQVPENLLHGHNII 2587
Query: 481 KVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASD 540
VKA D D G + Y++ I F I+ TG ++ + E + V
Sbjct: 2588 TVKASDGDFGTYANLYYEIVSEEMKKI---FLIDQTTGVITSKVTFDREKKDEYVVLLKV 2644
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--N 598
SL V+ ++V ++P F+ Y+ V + V ++ ++ +
Sbjct: 2645 SDGGGKFGFASLKVIVVDVN-------DNVPYFLLKEYKMVVSTTVEANQTILTVKAKDD 2697
Query: 599 DAFEQNDVSYDLLH-GYEEGVPFAVE--ERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
D + V + ++ ++ V +E E++G I Y Y F V +
Sbjct: 2698 DIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQF-FVRASDRGE 2756
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
+ V + + + + S ++ ++ G + ++ + GN T
Sbjct: 2757 PQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLH------MIGNYT-- 2808
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+F IA QD I++ G + Q+ LDRE+++ + + V+AE + + A V I
Sbjct: 2809 FKFSIAADQD---HFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFA-YADVLI 2864
Query: 776 YIEDENDNPPVFEHATYEGFIMENS-KIGTEIKMDNIIKATDADEGTNALFMYTLFGEG- 833
+ DENDN P F++ Y + ENS K+ + +K + ATDAD G N Y L +
Sbjct: 2865 DVRDENDNYPKFDNTFYSASVAENSEKVISLVK----VSATDADTGPNGDIRYYLESDTE 2920
Query: 834 --KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDN 889
+ +FD+D +G + + SLDRE + Y ++A D G +A+ + I I D NDN
Sbjct: 2921 NIQNIFDIDIYSGWITLL-TSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDN 2979
Query: 890 KPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
P F E V E L GT ++ + P
Sbjct: 2980 APVFKLPIEGLSV---FENALPGTVLINLLLIDP 3010
Score = 103 bits (246), Expect = 5e-20
Identities = 60/168 (35%), Positives = 92/168 (54%), Gaps = 9/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+GV A + Y ++SGN++ F +DS G L L LD + + + L +Q
Sbjct: 3311 VYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYE-----MSKFYFLTIQ 3365
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + A V I +LD+NDN P F + Y I++ E++ G +L V ATD+D
Sbjct: 3366 AIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDV 3425
Query: 338 NGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG TY ++ D G FSIDP++G ++V LDRE S +++ A
Sbjct: 3426 NGLVTYNIERGDNIGQFSIDPKNGTISVSRP--LDRETISHYTLEIQA 3471
Score = 99.1 bits (236), Expect = 8e-19
Identities = 113/466 (24%), Positives = 205/466 (43%), Gaps = 35/466 (7%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
F + +T+ D NDN P+F + Y S+ +A++ T+I KV A+D D G N + Y L
Sbjct: 3168 FSEIIITVNDINDNMPIFSMAQ-YRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMG 3226
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEV 559
++ FKI+ +TG + + +S E L V+A D + +S+A V + +
Sbjct: 3227 ENH----DYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGV---PKLHSIATVAVNI 3279
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEG 617
+ P P+F Y + N GT V ++ D D+ Y ++ G E+G
Sbjct: 3280 L--DINDNP--PEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQG 3335
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV--VDVNDERGV 675
F ++ +G + + L Y + F + + + NA V++ +D+ND
Sbjct: 3336 -KFKMDSTTGDLVLNATLD-YEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPT 3393
Query: 676 LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
L+ + +V E+ G+ I + T+ S + G V + I ++ +
Sbjct: 3394 FLQNLYR---INVNEDIFVGSKILDVKATDEDS---DVNGLVTYNIERGDNIGQFSIDPK 3447
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+GTI +PLDRE Y + + A ++G + I I D NDN P+F + Y
Sbjct: 3448 NGTISVSRPLDRETISHYTLEIQA-CDQGDPQRCNSVPININILDTNDNAPIFSSSNYSV 3506
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKE--MFDVDENTGVVKFIGD 851
+ EN +G K +DADE N YT G E +F ++++ +
Sbjct: 3507 VLQENRLLGYVFL---TFKISDADETPNTT-PYTFDIRSGNEGGLFRLEQDGSLRTASRF 3562
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ + + + + ++ + T L S+A +++ I +E+ P +E
Sbjct: 3563 NHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLE 3608
Score = 98.7 bits (235), Expect = 1e-18
Identities = 125/488 (25%), Positives = 203/488 (41%), Gaps = 71/488 (14%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E+ IGT + L+A D DSG+N Q+ Y + E +D F +N
Sbjct: 881 FRLTESARIGTVVHCLHATDADSGINAQVTYALSVEC--------SD-------FTVNAT 925
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + + + L E + + L+I+A DGG+ L+ V V V DVND+ PVF Y F
Sbjct: 926 TGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFK 985
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRET 1112
V E VL ++A D D G NA + + ++ D F I TG + G LD E
Sbjct: 986 VREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYEN 1045
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ + L V A D G DVN+N +F PE D+
Sbjct: 1046 KQVHNLIVSAIDGG-DPSLTSDMSIVIMIIDVNEN--RF----------APEFDDF---- 1088
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTD----------FIGNGNGLILYSLPQRK 1222
VY+ ++EN P GT V V A D D I G+GL ++++ +
Sbjct: 1089 --------VYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQG 1140
Query: 1223 NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV---ELVSL 1279
+ +L + +T+ + + + Y ++E EN N P+ + +
Sbjct: 1141 SITSLSQLDAETKNFYWLTLC--AQDCAIVPLSNCVEVYIQVE-NENDNIPLTDKPVYYV 1197
Query: 1280 NLTE-HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
N+TE EN ++ + D D +T + +G L D + +++ +
Sbjct: 1198 NVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTG-----VIKTTER 1252
Query: 1339 KYSRE--LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
K RE H++ D + ++VV + D+NDNSP+F R +P++A
Sbjct: 1253 KLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF--DQRVYKVQVPSSAT 1310
Query: 1397 FGYQVMQL 1404
+ Q+
Sbjct: 1311 VNQSIFQV 1318
Score = 97.1 bits (231), Expect = 3e-18
Identities = 150/653 (22%), Positives = 267/653 (40%), Gaps = 93/653 (14%)
Query: 773 VTIYIEDENDN-PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT---NALFMYT 828
+ Y+E + +N +F+ Y G+I + + E++ + K AD G +A T
Sbjct: 2911 IRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVT 2970
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIM---YKLSLVARDTGGLSSEAELIIMIGD 885
+ ++ D ++N V K + L + + ++L+ D E + I+ GD
Sbjct: 2971 I-----KIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGD 3025
Query: 886 ENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFAL---------DVDQLGP 936
+ + +F QI ++ ++ I + + + + KF D++ P
Sbjct: 3026 K---QAQF-QIGKSGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTP 3081
Query: 937 LFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK 989
L P E+I IGTT++++ A+D D F S++ S AD
Sbjct: 3082 YCLKPRYHISTNESISIGTTLVEVKAIDFD----------FQSKLRFYLSGKGADD---- 3127
Query: 990 RYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVF 1045
F I + G + VA +L E+ +++L DG + + + V D+ND+ P+F
Sbjct: 3128 --FSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIF 3185
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
Y +V E ++ KV A D DFG N + Y + + D F+IS TG++ ++
Sbjct: 3186 SMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDY-FKISKSTGIIRLH 3244
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
LDRET + LTV A D G D+NDN P ++ + +
Sbjct: 3245 KSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNIL-DINDN-PPEFSMRQY----SCKI 3298
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPI------GTTVAKVFANDTDFIGNGNGLILYSLP 1219
E + H E V + I NA I G K + T N + Y +
Sbjct: 3299 LENATHGTE-VCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMS 3357
Query: 1220 Q----RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
+ + G P LS+ A + +++ D+ D + P F+ Y + + E++ +
Sbjct: 3358 KFYFLTIQAIDGGTPPLSNNAYVNISILDIND-----NSPTFLQNLYRINVNEDIFVGSK 3412
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
++ + T+ + E +I + F IDP+NGT+ + R DRE Y + ++A
Sbjct: 3413 ILDVKATDEDSDVNGLVTYNIERGDNIGQ-FSIDPKNGTISVSRPLDRETISHYTLEIQA 3471
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
Q + V + + I D NDN+P F++ N +V
Sbjct: 3472 CDQG-----------------DPQRCNSVPININILDTNDNAPIFSSSNYSVV 3507
Score = 93.5 bits (222), Expect = 4e-17
Identities = 110/432 (25%), Positives = 189/432 (43%), Gaps = 44/432 (10%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS-GLNGQIRYEFNSEVYI 976
II+V +N+FA + D + EN P GT ++ + A D+D+ LN +I Y
Sbjct: 1073 IIDVN-ENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITG---- 1127
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVR 1032
D L + F +N++ G + L E++ + L + A D L++ + V
Sbjct: 1128 ------GDGLGI---FAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVY 1177
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
+ V++ ND+ P+ K Y NV EA + + A D D +TY I +
Sbjct: 1178 IQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGY 1237
Query: 1093 FEISPLTGVL-SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
FEI TGV+ + +LDRE + ++IL V DNG D+NDNSP+F
Sbjct: 1238 FEIDSKTGVIKTTERKLDRENQAEHILEVAISDNG-SPVLSSTSRIVVSVLDINDNSPEF 1296
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
+ + + P + ++ +S+ + + EN I ++ + I +
Sbjct: 1297 --DQRVYKVQVPSSATVN----QSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQR 1350
Query: 1212 GLILYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
G I + P + ++ G+P S TA V + VP + P+ + + E
Sbjct: 1351 GHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTA--RVNIVVVPVNPNSQNAPLIVRKTSE 1408
Query: 1264 --LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
+++ EN + P LV+ L +N ++ Y I N ND + TF I NG + L +
Sbjct: 1409 NVVDLTEN-DKPGFLVTQILAVDDDNDQLWYNISNGNDDN---TFYIGQDNGNILLSKYL 1464
Query: 1322 DREVKDTYEVIV 1333
D E + +Y + +
Sbjct: 1465 DYETQQSYNLTI 1476
Score = 90.2 bits (214), Expect = 4e-16
Identities = 84/320 (26%), Positives = 137/320 (42%), Gaps = 28/320 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDN--VPIFLDTPYHVTVDELTPTGEKAFIFLIAP---- 123
I G +++ +S+ + I DVN+N P F D Y V E P G F+ +
Sbjct: 1056 IDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKG--TFVMNVTARDMD 1113
Query: 124 ---IGPSLTIPLTVPRGLTIFK-----DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE 175
+ +T +T GL IF I + + T N ++ + D L
Sbjct: 1114 TVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKN--FYWLTLCAQDCAIVPLS 1171
Query: 176 SSHKPVLLLRKVLD-YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE 234
+ + + + D DK V + + EI+ + A D D+ T+ Y
Sbjct: 1172 NCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEII---TLKAFDPDIDPTQTITYN 1228
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
++SGN F +DS G + E LD E+ + +L+V S +P+ ++ +R+ +
Sbjct: 1229 IVSGNLVGYFEIDSKTG-VIKTTERKLDRENQAE---HILEVAISDNGSPVLSSTSRIVV 1284
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AF 352
+LD+NDN PEF+ Y + + + S+ QV A D D GENG TY + KG F
Sbjct: 1285 SVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKF 1344
Query: 353 SIDPRSGWLTVRNQTVLDRE 372
ID + G + + D E
Sbjct: 1345 RIDSQRGHIHIAKPLDSDNE 1364
Score = 90.2 bits (214), Expect = 4e-16
Identities = 111/466 (23%), Positives = 193/466 (41%), Gaps = 32/466 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + + NVE+ + D NDN P + Y S + +GT + +VKA+D D Q+ +
Sbjct: 3060 DGKFTAKANVEIDVKDINDNTPYCLKPR-YHISTNESISIGTTLVEVKAIDFDF-QSKLR 3117
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANP-SERRYSLAV 554
Y + ++ F I +G + VA + E + A Q ++ +S +
Sbjct: 3118 FYLSGKGAD-----DFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEII 3172
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN-DVSYDLLH 612
+T+ ++P F A Y V + + T + ++ D F N + Y L+
Sbjct: 3173 ITV------NDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMG 3226
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
E F + + +G+I + L R +++ A L + V+++D+ND
Sbjct: 3227 --ENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDIND 3284
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+S I ++ + G + +++ T SI ++ + I + +
Sbjct: 3285 NPPEFSMRQYSCKI--LENATHGTEVCKVYAT---SIDIGVNADIHYFIMSGNEQGKFKM 3339
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G + LD E Y +T+ A + G + V I I D NDN P F
Sbjct: 3340 DSTTGDLVLNATLDYEMSKFYFLTIQA-IDGGTPPLSNNAYVNISILDINDNSPTFLQNL 3398
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIG 850
Y + E+ +G++I +D +KATD D N L Y + G+ F +D G + +
Sbjct: 3399 YRINVNEDIFVGSKI-LD--VKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTIS-VS 3454
Query: 851 DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
LDRE Y L + A D G + + I I D NDN P F+
Sbjct: 3455 RPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFS 3500
Score = 87.4 bits (207), Expect = 3e-15
Identities = 83/324 (25%), Positives = 149/324 (45%), Gaps = 29/324 (8%)
Query: 61 FDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG----EKA 116
F E ++ G N A S+ + + DVNDN P+F++ PY+ TV P G +
Sbjct: 2101 FVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVK 2160
Query: 117 FIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRD-KPNTPNSDVHYSIVSGNDDGHFALE 175
I L + + L G D ++ + K + + +Y + DG
Sbjct: 2161 AIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPC 2220
Query: 176 SSHKPVLLLRKVLDYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
SS P+ + KV+D +K+F V + ++ + +I+ + +G +L Y
Sbjct: 2221 SSEAPLQV--KVIDRSMPVFEKQFYTVSVKEDVEMYSALSV-----SIEAESPLGRSLIY 2273
Query: 234 ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
+ S + + F +D GS+F+ ELD + + ++ + ++A+ + + A+ +
Sbjct: 2274 TISS--ESQSFEIDYNTGSIFVVNELDYE-----KISSHDVSIRATDSLSGVY-AEVVLS 2325
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--- 350
+ ++D+ND PE E D YN++I EN G +L++ ATD D G N + +Y ++ G
Sbjct: 2326 VSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNN 2385
Query: 351 --AFSIDPRSGWLTVRNQTVLDRE 372
F ID G L ++ T LD E
Sbjct: 2386 SELFYIDVTDGNLYLK--TPLDYE 2407
Score = 86.2 bits (204), Expect = 6e-15
Identities = 110/476 (23%), Positives = 194/476 (40%), Gaps = 39/476 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V + + + NDN P+ +Y ++ + I +KA DPD+ + Y+
Sbjct: 1170 LSNCVEVYIQVENENDNIPL-TDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYN 1228
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
+ + NL F+I+ TG + E + + H L V SD + + V
Sbjct: 1229 IV-SGNLV--GYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVS 1285
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
+++ + P+F Y+ V S+ + S+ Q+ +D+ E ++Y + G
Sbjct: 1286 VLDINDNS-------PEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSG 1338
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAV--ALQENANLSIVTNATVHVVDVND 671
+ F ++ + G I + L N +A + + + + V N V V+ N
Sbjct: 1339 KGKN-KFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARV-NIVVVPVNPNS 1396
Query: 672 ERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ L+ S + + EN G + QI + + + + I+N D
Sbjct: 1397 QNAPLIVRKTSENVVDLTENDKPGFLVTQILAVD------DDNDQLWYNISNGNDDNTFY 1450
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
++G I K LD E + Y +T+ G + + + + D NDNPP F
Sbjct: 1451 IGQDNGNILLSKYLDYETQQSYNLTI--SVTDGTFTA--FTNLLVQVIDINDNPPQFAKD 1506
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY--TLFGEGKEMFDVDENTGVVKF 848
Y I EN + + I + ATD DE + T +F +D +G V
Sbjct: 1507 VYHVNISENIEEESVIMQ---LHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNV-I 1562
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ LD EK + L + +D G G + A++I+ + D ND+ PEF SKV
Sbjct: 1563 VTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKV 1618
Score = 85.8 bits (203), Expect = 8e-15
Identities = 85/310 (27%), Positives = 137/310 (44%), Gaps = 29/310 (9%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-----KAFIF-----LIAPIG 125
+ +A +V + ++D+NDN P L YH++ +E G KA F L +
Sbjct: 3062 KFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLS 3121
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGH-FALESSHKPVLLL 184
++ + I K A DR+ TP Y +V+ DG F E + ++ +
Sbjct: 3122 GKGADDFSIGKESGILKVASALDRE--TTPK----YKLVAHVQDGKDFTQECFSEIIITV 3175
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF 244
+ D Q + ++ +HA+D+D GV ++Y L+ G + F
Sbjct: 3176 NDINDNMPIFSMAQYRVSVPEDAQLNTLI--TKVHAMDKDFGVNRQIKYSLM-GENHDYF 3232
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
+ G + L K LD + + F L V+A P + A V + +LD+NDN P
Sbjct: 3233 KISKSTGIIRLHKSLDRET-----ISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPP 3287
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLT 362
EF + Y+ I+EN +G V +V AT D G N + Y + + +G F +D +G L
Sbjct: 3288 EFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDL- 3346
Query: 363 VRNQTVLDRE 372
V N T LD E
Sbjct: 3347 VLNAT-LDYE 3355
Score = 84.2 bits (199), Expect = 2e-14
Identities = 95/422 (22%), Positives = 177/422 (41%), Gaps = 33/422 (7%)
Query: 991 YFVINERHGHV-IVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVF 1045
YF I+ + G + R L E+ E L ++ D G+ L+ + V V D+ND+ P F
Sbjct: 1237 YFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEF 1296
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ Y V + + + +V A D+D G+N +TY I+ F I G + +
Sbjct: 1297 DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIA 1356
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
LD + E + + + A DNG VN NS L+ K E
Sbjct: 1357 KPLDSDNE--FEIHIKAEDNGIPKKSQTARVNIVVV-PVNPNSQNA----PLIVRKTSEN 1409
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS-LPQRKNQ 1224
N + ++ A ++N + ++ ++T +IG NG IL S + Q
Sbjct: 1410 VVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQ 1469
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPV-FISRYYELEIEENVNAPVELVSLNLTE 1283
Q+ L + + ++++D P F Y + I EN+ ++ L+ T+
Sbjct: 1470 QSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATD 1529
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
E+ K+ Y++ D F ID +G + + + R + +K ++
Sbjct: 1530 RDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQ--------------RLDFEKTAQH 1575
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
+ +I V + G Y K++V + D ND+ P+FT + + + +P +A G ++ +
Sbjct: 1576 I--LIVFVKDQGAPGKRNY-AKIIVNVHDHNDHHPEFT--AKIIQSKVPESAAIGSKLAE 1630
Query: 1404 LK 1405
++
Sbjct: 1631 VR 1632
Score = 84.2 bits (199), Expect = 2e-14
Identities = 128/478 (26%), Positives = 195/478 (40%), Gaps = 65/478 (13%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I + P+N ++ DQ +PEN+ G II + A D D G + YE SE
Sbjct: 2555 ISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSE----- 2609
Query: 979 SKLSADALEVKRYFVINERHGHVI--VARSLPPESEFRLNISALDGGNLNDNISVRVFVK 1036
E+K+ F+I++ G + V + E+ + + DGG S++V V
Sbjct: 2610 --------EMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVV 2661
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP---- 1092
DVND+ P F Y V + + V A D D N ++ + I D
Sbjct: 2662 DVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDV 2721
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
EI+ TG + + + + Y V A D G + + N P F
Sbjct: 2722 IEINEKTGDIVFKSKAESYGVNSYQFFVRASDRG-EPQFHSEVPVSIEIIETDANIPTFE 2780
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
LL K E+ + MI Y T + A+ F+ + +G
Sbjct: 2781 KSSVLL--KIIESTP-PGTVLTKLHMIGNY-----------TFKFSIAADQDHFMISDSG 2826
Query: 1213 -LILYSLPQRKNQQ--NLGLPSLSSTAILMVTVADVPDEV--EMSDKPVFISRYYELEIE 1267
LIL R+ Q+ NL + + +ST + ADV +V E + P F + +Y +
Sbjct: 2827 ELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVA 2886
Query: 1268 ENVNAPVELVSLNLT--EHYENFKMRYYILNENDTD-IRRTFVIDPRNGTLYLVRSPDRE 1324
EN + LV ++ T + N +RYY+ E+DT+ I+ F ID +G + L+ S DRE
Sbjct: 2887 ENSEKVISLVKVSATDADTGPNGDIRYYL--ESDTENIQNIFDIDIYSGWITLLTSLDRE 2944
Query: 1325 VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIK--DVNDNSPKF 1380
V+ Y V +A D G K+D KV V IK D NDN+P F
Sbjct: 2945 VQSEYNFKV-----------------IAAD--NGHPKHDAKVPVTIKIVDYNDNAPVF 2983
Score = 83.4 bits (197), Expect = 4e-14
Identities = 58/162 (35%), Positives = 88/162 (54%), Gaps = 8/162 (4%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE+++ Y + + ++ G + + + I I D NDN PV + + E+++IG
Sbjct: 832 LDRERQNEYVLNITV-YDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIG 890
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T + + + ATDAD G NA Y L E + F V+ TG ++ + LDREK+ Y L
Sbjct: 891 TVV---HCLHATDADSGINAQVTYALSVECSD-FTVNATTGCLR-LNKPLDREKQDNYAL 945
Query: 864 SLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+ A+D G LSSEA + +++ D NDN P F E KVR
Sbjct: 946 HITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVR 987
Score = 81.8 bits (193), Expect = 1e-13
Identities = 54/160 (33%), Positives = 86/160 (53%), Gaps = 14/160 (8%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
T ++ + + D + S DS G L L++ LD + + +++ ++ + S + P+ A
Sbjct: 2808 TFKFSIAADQDHFMIS-DS--GELILQQTLDREQQ---ESHNLIVVAETSTV--PVFFAY 2859
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP- 348
A V I++ D NDN P+F+ FY+ S+ EN S+++V ATD D G NG+ Y L+
Sbjct: 2860 ADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDT 2919
Query: 349 ---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ F ID SGW+T+ T LDRE S KV A +
Sbjct: 2920 ENIQNIFDIDIYSGWITL--LTSLDREVQSEYNFKVIAAD 2957
Score = 81.4 bits (192), Expect = 2e-13
Identities = 118/464 (25%), Positives = 192/464 (41%), Gaps = 46/464 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV----------KAVDPDLGQNG 493
N+ + +LDANDN P FV N Y ++ +A +G+ + KV + D D+G NG
Sbjct: 1797 NIIIHILDANDNIPYFV-QNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNG 1855
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYS 551
MV Y + +L + FKI+ TG + + E + V SD P +
Sbjct: 1856 MVEYHI--VDDLA-KNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDM-GKPKLHSTT 1911
Query: 552 LAVVTIEVTRGTKGNKPDIPD-FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
A VTI V N D P F + V Q+ DA + + + +D+
Sbjct: 1912 TAHVTIRVI-----NVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDA-DNDTLRFDI 1965
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
+ G F +E+ +G+IT + N D+ + S + + V+
Sbjct: 1966 VDGNTNEC-FQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAI 2024
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDD 729
D + ++ F + N+ A IG + ++ GN NV + I N + D
Sbjct: 2025 DSNFAFQRESYRFSAF--ENNTKVATIGLV------NVIGNTLDENVEYRILNPTQLFD- 2075
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGA--GIYQVTIYIEDENDNPP 785
I I+ T DRE +D+YR+ V A+ G+ S + + I + D NDN P
Sbjct: 2076 IGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCP 2135
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
+F + Y + + GT I +KA D D N Y L E+F +D +G
Sbjct: 2136 LFVNMPYYATVSIDDPKGTIIMQ---VKAIDLDSAENGEVRYELKKGNGELFKLDRKSGE 2192
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEN 887
+ I ++ + Y+L++ A D SSEA L + + D +
Sbjct: 2193 LS-IKQHVEGHNR-NYELTVAAYDGAITPCSSEAPLQVKVIDRS 2234
Score = 77.0 bits (181), Expect = 4e-12
Identities = 79/334 (23%), Positives = 144/334 (43%), Gaps = 18/334 (5%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + V+D ND++P F T+Y+ +V E L KV ATDAD G N ++ Y+++ +
Sbjct: 2862 VLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTEN 2921
Query: 1091 LP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
+ F+I +G +++ LDRE + +Y V+A DNG D NDN+
Sbjct: 2922 IQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNG-HPKHDAKVPVTIKIVDYNDNA 2980
Query: 1149 PKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG 1208
P F +E + L ++++I IE+ V+ F
Sbjct: 2981 P---VFKLPIEGLSVFENALPGTVLINLLLI---DPDIEKQEMDFFIVSG--DKQAQFQI 3032
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-EMSDK-PVFISRYYELEI 1266
+G + + P + Q S+ +T A+V +V +++D P + Y +
Sbjct: 3033 GKSGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHIST 3092
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
E+++ LV + + K+R+Y+ + D F I +G L + + DRE
Sbjct: 3093 NESISIGTTLVEVKAIDFDFQSKLRFYLSGKGADD----FSIGKESGILKVASALDRETT 3148
Query: 1327 DTYEVIVRAERQK-YSRELPHMIYPVAEDVLEGM 1359
Y+++ + K +++E I D+ + M
Sbjct: 3149 PKYKLVAHVQDGKDFTQECFSEIIITVNDINDNM 3182
Score = 75.8 bits (178), Expect = 9e-12
Identities = 108/465 (23%), Positives = 182/465 (39%), Gaps = 42/465 (9%)
Query: 940 IPENIPIGTT----IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
IPEN +G T ++ L GLN +++Y S K + + I
Sbjct: 68 IPEN-SLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIR 126
Query: 996 ERHGHVIVARSLPPESEFRLNISA-LDGGNLND---NISVRVFVKDVNDHFPVFKKTWYN 1051
R +V++ R E R+ L N++ ++ + V D ND P+F T Y
Sbjct: 127 TRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYT 186
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
+ E + + KV A DAD G N + Y+ D++ F I P TG +++ +L
Sbjct: 187 VVIPEDTPKYQSILKVTADDADLGINGEI-YYSLLMDSEY-FAIHPTTGEITLLQQLQYA 244
Query: 1112 TEDKYILTVVARDNGX----XXXXXXXXXXXXXXXDVNDNSPKFY--AFDELLEWKHPEA 1165
+ LTVVA D G VN +P+ + F + +P
Sbjct: 245 ENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLI 304
Query: 1166 DELSNHNFESV-MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
+ N + + + + I + P GT + K ++ N L Q+
Sbjct: 305 YGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFA--HLNQQHFI 362
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDK--PVFISRYYELEIEEN--VNAPVELVSLN 1280
NL L + VP +++ K P+F YE+ I E +N PV + ++
Sbjct: 363 YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVS 422
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ +N + I+ N+ D F I+P +G LY + D E K +Y + V A
Sbjct: 423 DPDLGKNALVYLEIVGGNEGD---EFRINPDSGMLYTAKQLDAEKKSSYTLTVSA----- 474
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNR 1385
+ + + + KV + ++D+NDN P F N N+
Sbjct: 475 ----------IDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNK 509
Score = 75.4 bits (177), Expect = 1e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 23/263 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +++LD NDN+P F+ NLY ++ + VG+ I VKA D D NG+V Y+++R N
Sbjct: 3380 VNISILDINDNSPTFL-QNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDN 3438
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I+P GT+SV+ E + L ++A DQ +P +R + + I +
Sbjct: 3439 I---GQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQ-GDP--QRCNSVPININIL-D 3491
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV---SYDLLHGYEEGVP 619
T N P F + Y + N +G +++DA E + ++D+ G E G+
Sbjct: 3492 TNDN---APIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGL- 3547
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQ--ENANLSIVTNATVHVVDVNDERGVLL 677
F +E+ + T SR+N + D + ++ +N + ++A V V + + + +
Sbjct: 3548 FRLEQDGSLRTA----SRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPI 3603
Query: 678 KGAHSPIIFHVKENSAGAAIGQI 700
I +++ +GA IG++
Sbjct: 3604 VTPLEVTINSFEDDFSGAFIGKV 3626
Score = 71.7 bits (168), Expect = 1e-10
Identities = 73/277 (26%), Positives = 123/277 (44%), Gaps = 27/277 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-EKAFIFLIAP-IGPSLTIPLTV 134
+S + V + +E+ NDN+P+ Y+V V E + E + P I P+ TI +
Sbjct: 1170 LSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNI 1229
Query: 135 PRGLTI--FKD------IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
G + F+ I+ +R K + N H V+ +D+G L S+ + V+ +
Sbjct: 1230 VSGNLVGYFEIDSKTGVIKTTER-KLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLD 1288
Query: 187 VLDYDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
+ D D+ V + S +++ I +HAID D G + Y + SG + F
Sbjct: 1289 INDNSPEFDQRVYKVQVPSSATVNQSIF---QVHAIDSDSGENGRITYSIKSGKGKNKFR 1345
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN--- 302
+DS G + + K LD D N F + ++A P K+ ARV I ++ +N N
Sbjct: 1346 IDSQRGHIHIAKPLDSD-------NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQN 1398
Query: 303 --LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
L + + + EN GF V Q++A D D +
Sbjct: 1399 APLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQ 1435
Score = 68.5 bits (160), Expect = 1e-09
Identities = 113/495 (22%), Positives = 212/495 (42%), Gaps = 50/495 (10%)
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
PVF Y S+K + ++ + + + LG++ ++Y + S F+I+ N
Sbjct: 2236 PVF-EKQFYTVSVKEDVEMYSALSVSIEAESPLGRS--LIYTISSESQ-----SFEIDYN 2287
Query: 517 TGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
TG++ V E H + + A+D + Y+ V+++ + P+I +
Sbjct: 2288 TGSIFVVNELDYEKISSHDVSIRATDSLSGV----YAEVVLSVSIM-DVNDCYPEIESDI 2342
Query: 575 GAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSY--DLLHGYEEGVPFAVEERSGVIT 630
Y + N GT + +I ND+ +SY + ++G F ++ G +
Sbjct: 2343 ---YNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLY 2399
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
+ L Y + Y V ++++ + S+ + + V + R + K + II VK+
Sbjct: 2400 LKTPLD-YEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYDSII-PVKD 2457
Query: 691 --NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFTQKPLD 745
++A + + T +S G V A +D++D ++ G +D
Sbjct: 2458 LNDNAPCFVEPSYFTKVSVAAVRGQF-VALPKAYDKDISDTDSLEYKIVYGNELQTYSID 2516
Query: 746 R-----EKRDVYRMTVIAEFNKGVISGAGIY----QVTIYIEDENDNPPVFEHATYEGFI 796
+ +++ T + + G++ ++ I + EN P+F+ +TYE +
Sbjct: 2517 KLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQV 2576
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDSLDR 855
EN G I +KA+D D GT A Y + E K++F +D+ TGV+ + DR
Sbjct: 2577 PENLLHGHNIIT---VKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVIT-SKVTFDR 2632
Query: 856 EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
EKK Y + L D GG A L +++ D NDN P F + + K+ + + N
Sbjct: 2633 EKKDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYF--LLKEYKMVVSTTVEANQ--- 2687
Query: 916 FTIIEVKPKNKFALD 930
TI+ VK K+ +D
Sbjct: 2688 -TILTVKAKDDDIVD 2701
Score = 68.5 bits (160), Expect = 1e-09
Identities = 65/236 (27%), Positives = 101/236 (42%), Gaps = 21/236 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I+V+ +N D + EN +++K++A D D+G NG IRY
Sbjct: 2863 LIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRY--------- 2913
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFV 1035
L +D ++ F I+ G + + SL E SE+ + A D G+ + V V +
Sbjct: 2914 --YLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTI 2971
Query: 1036 K--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
K D ND+ PVFK +V E VL + D D + + +FI D F
Sbjct: 2972 KIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDI-EKQEMDFFIVSGDKQAQF 3030
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+I +G L + LDRE Y L+++A D D+NDN+P
Sbjct: 3031 QIGK-SGELFIAKPLDREQLMFYNLSIIATDG----KFTAKANVEIDVKDINDNTP 3081
Score = 68.1 bits (159), Expect = 2e-09
Identities = 99/420 (23%), Positives = 187/420 (44%), Gaps = 50/420 (11%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F + E++P GT + + A+D D G N +I++ E + + F I++
Sbjct: 983 IFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEET------------QDEELFRIDK 1030
Query: 997 RHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDH--FPVFKKTWY 1050
G + L E++ L +SA+DGG +L ++S+ + + DVN++ P F Y
Sbjct: 1031 HTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVY 1090
Query: 1051 NFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
V+E + + V A D D N+ +TY I D F ++ + S++ +LD
Sbjct: 1091 EGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLS-QLD 1149
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
ET++ Y LT+ A+D + NDN P D+ + + + E S
Sbjct: 1150 AETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENE-NDNIP---LTDKPVYYVN--VTEAS 1203
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ--RKNQ--- 1224
N E ++ + + I+ I + I + G+I + + R+NQ
Sbjct: 1204 VENVE-IITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEH 1262
Query: 1225 ------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVEL 1276
+ G P LSST+ ++V+V D+ D + P F R Y++++ + VN +
Sbjct: 1263 ILEVAISDNGSPVLSSTSRIVVSVLDIND-----NSPEFDQRVYKVQVPSSATVNQSIFQ 1317
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
V ++ EN ++ Y I + + F ID + G +++ + D + + +E+ ++AE
Sbjct: 1318 VHAIDSDSGENGRITYSIKSGKG---KNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAE 1372
Score = 67.3 bits (157), Expect = 3e-09
Identities = 72/312 (23%), Positives = 134/312 (42%), Gaps = 21/312 (6%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLI-APIGPS--LTIPL 132
+S+ + V + D+NDN P F Y V V + F + I + G + +T +
Sbjct: 1276 LSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSI 1335
Query: 133 TVPRGLTIFK-DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+G F+ D + +SD + I +D +S V ++ V+ +
Sbjct: 1336 KSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIV--VVPVN 1393
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGV---GATLRYELISGNDRKLFSLDS 248
+ L++ + + + +P + Q L V L Y + +GND F +
Sbjct: 1394 PNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQ 1453
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
NG++ L K LD + + Q+ + V TA + ++++D+NDN P+F
Sbjct: 1454 DNGNILLSKYLDYETQ---QSYNLTISVTDGTF-----TAFTNLLVQVIDINDNPPQFAK 1505
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEF-TYQLDDPK--GAFSIDPRSGWLTVRN 365
D Y+++I EN+ ++Q+ ATD+D+ + + + DP F ID SG + V
Sbjct: 1506 DVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQ 1565
Query: 366 QTVLDREAHSSL 377
+ ++ A L
Sbjct: 1566 RLDFEKTAQHIL 1577
Score = 66.9 bits (156), Expect = 4e-09
Identities = 45/155 (29%), Positives = 82/155 (52%), Gaps = 12/155 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D+ +L Y+++ GN+ + +S+D + G + L+ L+ + ++ VL + S
Sbjct: 2489 AYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDK-----SSTVLNISVS 2543
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ + TA AR++I LL N P F+ Y + ENL +G +++ V A+D D G
Sbjct: 2544 ---DGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYA 2600
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
Y++ ++ K F ID +G +T ++ DRE
Sbjct: 2601 NLYYEIVSEEMKKIFLIDQTTGVIT--SKVTFDRE 2633
Score = 66.1 bits (154), Expect = 7e-09
Identities = 49/166 (29%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 225 LGVGATLRYELISGNDRKLFSLDS--VNGSLFLEKELDLD--AEHNLQANTFVLQVQAS- 279
+G+ A ++Y +ISG+ KLF + V FL + + + +V++V+A
Sbjct: 91 VGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHV 150
Query: 280 ---QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
N +A + I++LD ND P F Y + I E+ P S+L+V A D D G
Sbjct: 151 HLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLG 210
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
NGE Y L F+I P +G +T+ Q +H L + Y
Sbjct: 211 INGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAY 256
Score = 66.1 bits (154), Expect = 7e-09
Identities = 77/361 (21%), Positives = 147/361 (40%), Gaps = 27/361 (7%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
S+ + V DVND+ P+F Y V ++ +V A D D +N + Y ++ +
Sbjct: 2122 SIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNG 2181
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+L F++ +G LS+ ++ + Y LTV A D ++ + P
Sbjct: 2182 EL-FKLDRKSGELSIKQHVEGHNRN-YELTVAAYDGAITPCSSEAPLQVKV---IDRSMP 2236
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI-- 1207
F + K E V M +IE +P+G ++ ++++
Sbjct: 2237 VFEKQFYTVSVK------------EDVEMYSALSVSIEAESPLGRSLIYTISSESQSFEI 2284
Query: 1208 --GNGNGLILYSLPQRK-NQQNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYE 1263
G+ ++ L K + ++ + + S + + V ++++D P S Y
Sbjct: 2285 DYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYN 2344
Query: 1264 LEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
L I EN + +++ +N T++ N K+ YYI + N + F ID +G LYL
Sbjct: 2345 LTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPL 2404
Query: 1322 DREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV--KVVVRIKDVNDNSPK 1379
D E + ++V + + +L Y + ++ +KD+NDN+P
Sbjct: 2405 DYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYDSIIPVKDLNDNAPC 2464
Query: 1380 F 1380
F
Sbjct: 2465 F 2465
Score = 65.7 bits (153), Expect = 9e-09
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 7/196 (3%)
Query: 222 DQDLGVGATL-RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
D+D G+ + R E++ GN F L + EL+ A N Q + L + A
Sbjct: 312 DKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAED 371
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
L P + A V I++ + N+P F + Y +SI E P V+++ +D D G+N
Sbjct: 372 LGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNAL 431
Query: 341 FTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
++ + F I+P SG L Q LD E SS + V A + + VG+ S
Sbjct: 432 VYLEIVGGNEGDEFRINPDSGMLYTAKQ--LDAEKKSSYTLTVSA--IDQANVGSRKQSS 487
Query: 399 RIAKWRRQPLETNAPL 414
K Q + N P+
Sbjct: 488 AKVKISVQDMNDNDPI 503
Score = 65.7 bits (153), Expect = 9e-09
Identities = 62/241 (25%), Positives = 104/241 (43%), Gaps = 27/241 (11%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++ V N + + DQ +P + + +I +++A+D DSG NG+I Y S
Sbjct: 1283 VVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSG---- 1338
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFV 1035
+ K F I+ + GH+ +A+ L ++EF ++I A D G + V + V
Sbjct: 1339 ---------KGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVV 1389
Query: 1036 KDVNDHFP----VFKKTWYN-FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
VN + + +KT N ++ E ++ ++ A D D N L Y I + D
Sbjct: 1390 VPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISNGNDD 1446
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I G + ++ LD ET+ Y LT+ D D+NDN P+
Sbjct: 1447 NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG----TFTAFTNLLVQVIDINDNPPQ 1502
Query: 1151 F 1151
F
Sbjct: 1503 F 1503
Score = 64.9 bits (151), Expect = 2e-08
Identities = 50/209 (23%), Positives = 97/209 (46%), Gaps = 11/209 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D V + Y + G++ FS+D NG++ + + LD + + + L++Q
Sbjct: 3416 VKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRET-----ISHYTLEIQ 3470
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + + I +LD NDN P F Y++ + EN G+ L +D D+
Sbjct: 3471 ACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETP 3530
Query: 338 N-GEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
N +T+ + + G F ++ + G L ++ + + ++++V+ T P +
Sbjct: 3531 NTTPYTFDIRSGNEGGLFRLE-QDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAW 3589
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPD 423
+ I + + P+ T PLE T F D
Sbjct: 3590 VVVKIIEESQYPPIVT--PLEVTINSFED 3616
Score = 63.7 bits (148), Expect = 4e-08
Identities = 74/265 (27%), Positives = 115/265 (43%), Gaps = 22/265 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI---GPSLTIPLTV 134
+A+ ++ V + D+NDN P F YHV + E E + L A L L
Sbjct: 1484 TAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEE-ESVIMQLHATDRDEDKKLFYHLHA 1542
Query: 135 ---PRGLTIFKDIRAFDRDKPNTPNSDV-----HYSIVSGNDDGHFALESSHKPVLLLRK 186
P L +F+ I + + T D H IV D G + K ++
Sbjct: 1543 TQDPSSLALFR-IDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIV---N 1598
Query: 187 VLDYDAGDKEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGVGATLRYELISGNDRKLFS 245
V D++ EF I+ S I + AID+D G A ++Y +I+GN +F
Sbjct: 1599 VHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFE 1658
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+D G + L L+++ + ++LQV+A L NP ++Q V I + ++ P+
Sbjct: 1659 IDPTFGIITLAGNLNIN-----KIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPK 1713
Query: 306 FEVDFYNISIVENLPNGFSVLQVMA 330
F + I I ENLP G V QV A
Sbjct: 1714 FPTNNIAIEIFENLPIGTFVTQVTA 1738
Score = 61.7 bits (143), Expect = 2e-07
Identities = 86/374 (22%), Positives = 147/374 (39%), Gaps = 39/374 (10%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
LNIS DG + +++ + N + P+F ++ Y V E + V A+D DF
Sbjct: 2538 LNISVSDGVH-TAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDF 2596
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
G ANL Y I + F I TGV++ DRE +D+Y++ + D G
Sbjct: 2597 GTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGG---GKFGF 2653
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
DVNDN P F L E+K V T+E N
Sbjct: 2654 ASLKVIVVDVNDNVPYFL----LKEYK------------------MVVSTTVEAN----Q 2687
Query: 1195 TVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
T+ V A D D + NG+ + + + Q+ N + + + + + ++
Sbjct: 2688 TILTVKAKDDDIVDNGS--VHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSY 2745
Query: 1255 PVFI--SRYYELEIEENVNAPVELVSLNLT-EHYENFKMRYYILNENDTDIRRTFVIDPR 1311
F+ S E + V +E++ + +E + I+ T +
Sbjct: 2746 QFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIG 2805
Query: 1312 NGTLYLVRSPDRE---VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVV 1368
N T + D++ + D+ E+I++ + +E H + VAE + V++
Sbjct: 2806 NYTFKFSIAADQDHFMISDSGELILQQTLDREQQE-SHNLIVVAETSTVPVFFAYADVLI 2864
Query: 1369 RIKDVNDNSPKFTN 1382
++D NDN PKF N
Sbjct: 2865 DVRDENDNYPKFDN 2878
Score = 61.3 bits (142), Expect = 2e-07
Identities = 101/395 (25%), Positives = 160/395 (40%), Gaps = 71/395 (17%)
Query: 844 GVVKFIGDSLDR--EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
G+V IG++LD E +I+ L D G +SS A + + + K + E +K
Sbjct: 2050 GLVNVIGNTLDENVEYRILNPTQLF--DIG-ISSGALKTTGVIFDREVKDLYRLFVE-AK 2105
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLN 954
++ N T I++ LDV+ PLF+ + + P GT I+++
Sbjct: 2106 SMLYDGMNSNVRRAVTSIDIS-----VLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVK 2160
Query: 955 ALDLDSGLNGQIRYEF---NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
A+DLDS NG++RYE N E++ K + L +K++ GH
Sbjct: 2161 AIDLDSAENGEVRYELKKGNGELFKLDRK--SGELSIKQHV-----EGH---------NR 2204
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+ L ++A DG + + VK ++ PVF+K +Y +V+E L +
Sbjct: 2205 NYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAE 2264
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
+ G+ +L Y I S FEI TG + V ELD E + +++ A D+
Sbjct: 2265 SPLGR--SLIYTI--SSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDS--LSGV 2318
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
DVND P+ E+D +Y TI ENA
Sbjct: 2319 YAEVVLSVSIMDVNDCYPEI------------ESD--------------IYNLTIPENAS 2352
Query: 1192 IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
GT + K+ A D D N + Y + Q N
Sbjct: 2353 FGTQILKINATDND--SGANAKLSYYIESINGQNN 2385
Score = 60.9 bits (141), Expect = 3e-07
Identities = 94/376 (25%), Positives = 158/376 (42%), Gaps = 47/376 (12%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKT 1048
F I+ G + V L E S ++I A D + + + V + DVND +P +
Sbjct: 2282 FEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESD 2341
Query: 1049 WYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQ----PSDTDLPFEISPLTGVLS 1103
YN + E A + ++L K++ATD D G NA L+Y+I+ ++++L F I G L
Sbjct: 2342 IYNLTIPENASFGTQIL-KINATDNDSGANAKLSYYIESINGQNNSEL-FYIDVTDGNLY 2399
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
+ LD E + + V +D+G S K +D ++ P
Sbjct: 2400 LKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKL-IYDSII----P 2454
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---------IGNGNGLI 1214
D N + P Y + A G VA A D D I GN L
Sbjct: 2455 VKDLNDN---APCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQ 2511
Query: 1215 LYSLPQRKN----QQNLGLPSLSSTAILMVTVAD----------VPDEVEMSDKPVFISR 1260
YS+ + Q L SST +L ++V+D + E P+F
Sbjct: 2512 TYSIDKLTGVISLQNMLNFTDKSST-VLNISVSDGVHTAYARLKISLLPENVYSPLFDQS 2570
Query: 1261 YYELEIEENVNAPVELVSLNLTE-HYENFKMRYY-ILNENDTDIRRTFVIDPRNGTLYLV 1318
YE ++ EN+ ++++ ++ + + YY I++E ++++ F+ID G +
Sbjct: 2571 TYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSE---EMKKIFLIDQTTGVITSK 2627
Query: 1319 RSPDREVKDTYEVIVR 1334
+ DRE KD Y V+++
Sbjct: 2628 VTFDREKKDEYVVLLK 2643
Score = 60.5 bits (140), Expect = 3e-07
Identities = 51/205 (24%), Positives = 93/205 (45%), Gaps = 15/205 (7%)
Query: 183 LLRKVLDYDAGDKEFQLVI--MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
LL +V+D + +F + + + I +E + + +HA D+D L Y L + D
Sbjct: 1489 LLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQ-LHATDRD--EDKKLFYHLHATQD 1545
Query: 241 RK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
LF +DS++G++ + + LD + + +L V P K A++ + +
Sbjct: 1546 PSSLALFRIDSISGNVIVTQRLDFE-----KTAQHILIVFVKDQGAPGKRNYAKIIVNVH 1600
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID 355
D ND+ PEF + E+ G + +V A D+D G N E Y + + F ID
Sbjct: 1601 DHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEID 1660
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMK 380
P G +T+ +++ L++K
Sbjct: 1661 PTFGIITLAGNLNINKIQEYMLQVK 1685
Score = 60.5 bits (140), Expect = 3e-07
Identities = 102/443 (23%), Positives = 170/443 (38%), Gaps = 43/443 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRY-------EFNSEV-YIPPSKLSADALEVKRY 991
IPEN GT I+K+NA D DSG N ++ Y + NSE+ YI + + Y
Sbjct: 2347 IPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDY 2406
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF------VKDVNDHFPVF 1045
I H V V P R N+ + G L IS ++ VKD+ND+ P F
Sbjct: 2407 EQIKYHHIVVNVKDHGSPSLSSRSNVF-ITGRILCRFISYKLIYDSIIPVKDLNDNAPCF 2465
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ Y V A + + A D D +L Y I + + I LTGV+S+
Sbjct: 2466 VEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQ 2525
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
L+ + +L + D N SP F E + PE
Sbjct: 2526 NMLNFTDKSSTVLNISVSDG----VHTAYARLKISLLPENVYSPLF--DQSTYEAQVPE- 2578
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL--YSLPQRKN 1223
+ L HN ++ + A + + I G+I + + K
Sbjct: 2579 NLLHGHN---IITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKK 2635
Query: 1224 QQNLGLPSLS------STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+ + L +S A L V V DV D V P F+ + Y++ + V A ++
Sbjct: 2636 DEYVVLLKVSDGGGKFGFASLKVIVVDVNDNV-----PYFLLKEYKMVVSTTVEANQTIL 2690
Query: 1278 SLNLTEH--YENFKMRYYILNE-NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
++ + +N + + I+ + ND ++ I+ + G + + ++Y+ VR
Sbjct: 2691 TVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVR 2750
Query: 1335 AERQKYSRELPHMIYPVAEDVLE 1357
A + H PV+ +++E
Sbjct: 2751 ASDR--GEPQFHSEVPVSIEIIE 2771
Score = 60.1 bits (139), Expect = 5e-07
Identities = 92/370 (24%), Positives = 161/370 (43%), Gaps = 43/370 (11%)
Query: 36 LAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIG--AGLNQISAYLSVTVYIEDVNDN 93
+A D + SDS + +++ L + E +L+ + + + AY V + + D NDN
Sbjct: 2813 IAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDN 2872
Query: 94 VPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPSLTIPLTVPRGLTIFKDIRAFD 148
P F +T Y +V E EK + A GP+ I + ++I D
Sbjct: 2873 YPKFDNTFYSASVAE---NSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDID 2929
Query: 149 ---------RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL 199
S+ ++ +++ D+GH + PV + K++DY+ F+L
Sbjct: 2930 IYSGWITLLTSLDREVQSEYNFKVIAA-DNGH-PKHDAKVPVTI--KIVDYNDNAPVFKL 2985
Query: 200 VIMASGKRIHKEILFPEPIHA----IDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL 255
I G + + L P + ID D+ + + ++SG+ + F + +G LF+
Sbjct: 2986 PI--EGLSVFENAL-PGTVLINLLLIDPDIEK-QEMDFFIVSGDKQAQFQIGK-SGELFI 3040
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
K LD + Q + L + A+ + TA+A VEI++ D+NDN P Y+IS
Sbjct: 3041 AKPLDRE-----QLMFYNLSIIAT---DGKFTAKANVEIDVKDINDNTPYCLKPRYHIST 3092
Query: 316 VENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
E++ G ++++V A D D F Y FSI SG L V + LDRE
Sbjct: 3093 NESISIGTTLVEVKAIDFDFQSKLRF-YLSGKGADDFSIGKESGILKV--ASALDRETTP 3149
Query: 376 SLRMKVYAKE 385
++ + ++
Sbjct: 3150 KYKLVAHVQD 3159
Score = 59.3 bits (137), Expect = 8e-07
Identities = 58/253 (22%), Positives = 104/253 (41%), Gaps = 19/253 (7%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D+GV + Y ++ + F +DS G++ L ++LD + + V + +L
Sbjct: 1848 DADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKL 1907
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
++ T A V I ++++ND P F N+++ V QV A D D + F
Sbjct: 1908 HS---TTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD-NDTLRF 1963
Query: 342 TYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIA 401
+ F I+ +G +T RN +L+ E + V A + G F+ +
Sbjct: 1964 DIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASD------GIFSAILIVK 2017
Query: 402 KWRRQPLETNAPLEKTTYVFPD-KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV 460
+++N ++ +Y F + TK I VNV LD N +
Sbjct: 2018 IKVLSAIDSNFAFQRESYRFSAFENNTKVATI--------GLVNVIGNTLDENVEYRILN 2069
Query: 461 PSNLYEFSMKSNA 473
P+ L++ + S A
Sbjct: 2070 PTQLFDIGISSGA 2082
Score = 58.8 bits (136), Expect = 1e-06
Identities = 92/443 (20%), Positives = 175/443 (39%), Gaps = 38/443 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L S V V +LD NDN P F Y + NA GT + KV A D+G N + Y
Sbjct: 3268 KLHSIATVAVNILDINDNPPEF-SMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHY 3326
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
+ + FK++ TG + + + E + L ++A D P + +
Sbjct: 3327 FIMSGNE---QGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNIS 3383
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+++ + P F+ Y V ++ +G+ + ++ D E +DV+ + + E
Sbjct: 3384 ILDINDNS-------PTFLQNLYRINVNEDIFVGSKILDVKATD--EDSDVNGLVTYNIE 3434
Query: 616 EG---VPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVND 671
G F+++ ++G I+V L R Y E A Q + ++++D ND
Sbjct: 3435 RGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTND 3494
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI- 730
+ +S ++ +EN +G +F T S + + +
Sbjct: 3495 NAPIFSSSNYSVVL---QEN---RLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLF 3548
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ +DG++ T + +D + + + F+ G V + I +E+ PP+
Sbjct: 3549 RLEQDGSLRTASRFNHNLQDEF-VIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPL 3607
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKEMFDVDENTGVV 846
E+ G I + A+D D+ F + ++F++ NTG +
Sbjct: 3608 EVTINSFEDDFSGAFI---GKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKI 3664
Query: 847 KFIGDSLDREKKIMYKLSLVARD 869
I +LD +YKL++ D
Sbjct: 3665 YAI-SNLDIG---LYKLNVSVSD 3683
Score = 58.4 bits (135), Expect = 1e-06
Identities = 78/332 (23%), Positives = 135/332 (40%), Gaps = 25/332 (7%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPSLTIPLTV 134
+S+ V V ++DVNDN P+F Y V E P G + + IGP+ I ++
Sbjct: 957 LSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSL 1016
Query: 135 PRGLTIFKDIRAFDRDKP----------NTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
+D F DK + N VH IVS D G +L S V+++
Sbjct: 1017 KEET---QDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMI 1073
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQD-LGVGATLRYELISGNDRKL 243
V + + V K + F + A D D + + + + Y + G+ +
Sbjct: 1074 IDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGI 1133
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F+++ GS+ +LD + + N T Q A PL V I++ + NDN+
Sbjct: 1134 FAVND-QGSITSLSQLDAETK-NFYWLTLCAQDCAIV---PLSNC-VEVYIQVENENDNI 1187
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P + Y +++ E ++ + A D D TY + + G F ID ++G +
Sbjct: 1188 PLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVI 1247
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+ LDRE + ++V + V+ +
Sbjct: 1248 KT-TERKLDRENQAEHILEVAISDNGSPVLSS 1278
Score = 58.0 bits (134), Expect = 2e-06
Identities = 57/191 (29%), Positives = 86/191 (45%), Gaps = 16/191 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENI + I++L+A D D + ++ Y ++ PS L+ F I+ G
Sbjct: 1512 ISENIEEESVIMQLHATDRDE--DKKLFYHLHATQ--DPSSLAL--------FRIDSISG 1559
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+VIV + L E ++ L + D G + + V V D NDH P F V
Sbjct: 1560 NVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVP 1619
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ L +V A D D G NA + Y I + FEI P G++++ G L+ +
Sbjct: 1620 ESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQE 1679
Query: 1116 YILTVVARDNG 1126
Y+L V A D G
Sbjct: 1680 YMLQVKAVDLG 1690
Score = 57.2 bits (132), Expect = 3e-06
Identities = 99/437 (22%), Positives = 161/437 (36%), Gaps = 48/437 (10%)
Query: 988 VKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
+ F IN G +++ ++ ES F L + + + ++ + + D ND+ P F
Sbjct: 1753 INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYF 1812
Query: 1046 KKTWYNFNVEEA----QYTRRVLGK------VDATDADFGQNANLTYFIQPSDTDLPFEI 1095
+ Y + E+ Y +V + DAD G N + Y I F+I
Sbjct: 1813 VQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKI 1872
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
TG + + +LD ET Y V D G +VND P F
Sbjct: 1873 DSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNER 1932
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI 1214
+ + P FE+V + V A +N + + N+ I G+I
Sbjct: 1933 ELNVTLFLP--------TFENVFVRQV-SAKDADNDTLRFDIVDGNTNECFQIEKYTGII 1983
Query: 1215 L---YSLPQRKNQQNLGLPSLSSTAIL-MVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
+ + +N ++ L +S I + + + + F Y EN
Sbjct: 1984 TTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFEN- 2042
Query: 1271 NAPVELVSL-NLTEHYENFKMRYYILNENDT-DIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
N V + L N+ + + + Y ILN DI + G ++ DREVKD
Sbjct: 2043 NTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIF-----DREVKDL 2097
Query: 1329 YEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
Y + V A+ Y + +V +T D+ V+ DVNDN P F N P
Sbjct: 2098 YRLFVEAKSMLYD--------GMNSNVRRAVTSIDISVL----DVNDNCPLFV--NMPYY 2143
Query: 1389 TAIPTTAPFGYQVMQLK 1405
+ P G +MQ+K
Sbjct: 2144 ATVSIDDPKGTIIMQVK 2160
Score = 56.8 bits (131), Expect = 4e-06
Identities = 60/238 (25%), Positives = 99/238 (41%), Gaps = 14/238 (5%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI-RYEFNSEVYIP 977
I VK N +A ++ + P + P+ I+++N D D+G+NG I R E P
Sbjct: 276 ISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVN--DKDTGINGNIGRLEIVDGN--P 331
Query: 978 PSKLSADALEVK-RYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI--SVRVF 1034
A E K Y++ + H+ + + L + A D G SV +
Sbjct: 332 DGTFLLKAAETKDEYYIELNQFAHLNQQHFI-----YNLTLLAEDLGTPRRFAYKSVPIQ 386
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+K + + P+F + Y ++ E + ++ +D D G+NA + I + F
Sbjct: 387 IKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFR 446
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I+P +G+L +LD E + Y LTV A D D+NDN P F
Sbjct: 447 INPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIF 504
Score = 54.8 bits (126), Expect = 2e-05
Identities = 52/210 (24%), Positives = 93/210 (44%), Gaps = 26/210 (12%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ P FL + E+I +G+ I+ + A D DS +NG + Y I
Sbjct: 3385 LDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQ--- 3441
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLN--DNISVRVFVKD 1037
F I+ ++G + V+R L E S + L I A D G+ +++ + + + D
Sbjct: 3442 ----------FSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILD 3491
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLPFEIS 1096
ND+ P+F + Y+ ++E + V +DAD N T+ I+ + F +
Sbjct: 3492 TNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLE 3551
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNG 1126
G L + +D++++ V DNG
Sbjct: 3552 Q-DGSLRTASRFNHNLQDEFVIQVRVFDNG 3580
Score = 53.2 bits (122), Expect = 5e-05
Identities = 34/128 (26%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G A L YE++S +K+F +D G + ++ D E + + +V+ ++
Sbjct: 2589 VKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTG--VITSKVTFDRE---KKDEYVVLLK 2643
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
S K A +++ ++D+NDN+P F + Y + + + ++L V A D D +
Sbjct: 2644 VSDGGG--KFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVD 2701
Query: 338 NGEFTYQL 345
NG +Q+
Sbjct: 2702 NGSVHFQI 2709
Score = 49.6 bits (113), Expect = 6e-04
Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 11/169 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D + LR+ L SG FS+ +G L + LD + + V VQ
Sbjct: 3105 VKAIDFDFQ--SKLRFYL-SGKGADDFSIGKESGILKVASALDRETTPKYK---LVAHVQ 3158
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + + + + I + D+NDN+P F + Y +S+ E+ + +V A DKD G
Sbjct: 3159 DGK--DFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGV 3216
Query: 338 NGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + Y L + F I +G +R LDRE S + V A++
Sbjct: 3217 NRQIKYSLMGENHDYFKISKSTG--IIRLHKSLDRETISLFNLTVKAED 3263
Score = 46.8 bits (106), Expect = 0.005
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 13/136 (9%)
Query: 431 NIEYYDEQLMSF---VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
++ +D + S+ N+ + +LD ND +P+F P+ + K +++ KV A D
Sbjct: 149 HVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSIL-KVTADDA 207
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES-PILEGRH-ALFVEASDQPA-- 543
DLG NG + Y L S F I+P TG +++ + E H L V A D+ +
Sbjct: 208 DLGINGEIYYSLLMDSEY-----FAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWV 262
Query: 544 NPSERRYSLAVVTIEV 559
N + S V+I V
Sbjct: 263 NHQNHQASKTKVSISV 278
Score = 46.8 bits (106), Expect = 0.005
Identities = 67/279 (24%), Positives = 120/279 (43%), Gaps = 51/279 (18%)
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL-----LRKVLDYDAGDKEF 197
++RA DRD + N+++ YSI++GN F ++ + + L + K+ +Y K
Sbjct: 1630 EVRAIDRDSGH--NAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAV 1687
Query: 198 QLVIMASGKRIHKEIL----------FPEPIHAID--QDLGVG-----------ATLRYE 234
L +I I+ FP AI+ ++L +G +++ +
Sbjct: 1688 DLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFN 1747
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ISGN + F ++ G + + +D ++ F L V+ + N +++ + I
Sbjct: 1748 IISGNINESFRINPSTGVIVINGNIDYES-----IKVFNLTVKGT--NMAAESSCQNIII 1800
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV----------MATDKDQGENGEFTYQ 344
+LD NDN+P F + Y ++ E+ G VL+V D D G NG Y
Sbjct: 1801 HILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYH 1860
Query: 345 LDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+ D K F ID +G + + Q LD E ++ V
Sbjct: 1861 IVDDLAKNFFKIDSTTGAIELLRQ--LDYETNAGYTFDV 1897
Score = 45.2 bits (102), Expect = 0.014
Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 34/203 (16%)
Query: 940 IPENIPIGTTIIK----------LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK 989
+PE+ IG+ ++K L D D G+NG + Y ++ K
Sbjct: 1821 LPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDL-------------AK 1867
Query: 990 RYFVINERHGHVIVARSLPPESE----FRLNISALDGGNLNDNISVRVFVK--DVNDHFP 1043
+F I+ G + + R L E+ F + +S + L+ + V ++ +VND P
Sbjct: 1868 NFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPP 1927
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
VF + N + + + +V A DAD N L + I +T+ F+I TG+++
Sbjct: 1928 VFNERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVDGNTNECFQIEKYTGIIT 1984
Query: 1104 V-NGE-LDRETEDKYILTVVARD 1124
N E L+ E + Y L V A D
Sbjct: 1985 TRNFEILNNENDRDYALHVRASD 2007
Score = 45.2 bits (102), Expect = 0.014
Identities = 110/506 (21%), Positives = 204/506 (40%), Gaps = 66/506 (13%)
Query: 889 NKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGT 948
+K F++ +++ V + + + G GF ++V +DV+ P FL+ E + +
Sbjct: 2626 SKVTFDREKKDEYVVLLKVSDGGGKFGFASLKV-----IVVDVNDNVPYFLLKEYKMVVS 2680
Query: 949 TIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP 1008
T ++ N L + N V+ + S D VK INE+ G ++
Sbjct: 2681 TTVEANQTILTVKAKDDDIVD-NGSVHFQIVQKSNDKA-VKDVIEINEKTGDIVFKSKAE 2738
Query: 1009 PE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
+ ++ + A D G + + V + + + + + P F+K+ + E+ VL
Sbjct: 2739 SYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVL 2798
Query: 1065 GKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
K+ N T+ F +D D F IS +G L + LDRE ++ + L VVA
Sbjct: 2799 TKLHMI-------GNYTFKFSIAADQD-HFMISD-SGELILQQTLDREQQESHNLIVVA- 2848
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
+ D NDN PKF ++ F Y
Sbjct: 2849 ETSTVPVFFAYADVLIDVRDENDNYPKF------------------DNTF--------YS 2882
Query: 1184 ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
A++ EN+ ++ KV A D D NG+ + Y +N QN+ + S I ++T
Sbjct: 2883 ASVAENSEKVISLVKVSATDADTGPNGD-IRYYLESDTENIQNIFDIDIYSGWITLLTSL 2941
Query: 1244 DVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILN--EN--- 1298
D + E + K + + + + PV + ++ ++ FK+ L+ EN
Sbjct: 2942 DREVQSEYNFKVIAADNGHP---KHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALP 2998
Query: 1299 DTDIRRTFVIDP---RNGTLYLVRSPDREVKDTYEVIVRAE---RQKYSRELPHMIYPVA 1352
T + +IDP + + + S D++ + +++ E + RE M Y ++
Sbjct: 2999 GTVLINLLLIDPDIEKQEMDFFIVSGDKQAQ--FQIGKSGELFIAKPLDRE-QLMFYNLS 3055
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSP 1378
+G V + +KD+NDN+P
Sbjct: 3056 IIATDGKFTAKANVEIDVKDINDNTP 3081
Score = 44.8 bits (101), Expect = 0.018
Identities = 49/206 (23%), Positives = 95/206 (46%), Gaps = 21/206 (10%)
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSL 253
KE+++V+ + + ++ IL + A D D+ ++ ++++ ND+ + + +N
Sbjct: 2673 KEYKMVVSTTVEA-NQTIL---TVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEIN--- 2725
Query: 254 FLEKELDLDAEHNLQA---NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
EK D+ + ++ N++ V+AS P ++ V IE+++ + N+P FE
Sbjct: 2726 --EKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSS 2783
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
+ I+E+ P G + T N F + + + F I SG L + Q LD
Sbjct: 2784 VLLKIIESTPPG-----TVLTKLHMIGNYTFKFSIAADQDHFMISD-SGELIL--QQTLD 2835
Query: 371 REAHSSLRMKVYAKETNPSVVGTFAD 396
RE S + V A+ + V +AD
Sbjct: 2836 REQQESHNLIVVAETSTVPVFFAYAD 2861
Score = 37.1 bits (82), Expect = 3.7
Identities = 49/209 (23%), Positives = 90/209 (43%), Gaps = 23/209 (11%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM- 494
D Q + V + + +LD NDN P+F SN Y ++ N +G V K D D N
Sbjct: 3476 DPQRCNSVPININILDTNDNAPIFSSSN-YSVVLQENRLLGYVFLTFKISDADETPNTTP 3534
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSL 552
+D+ R+ N F++ + G++ A + L+ + V D P YS
Sbjct: 3535 YTFDI-RSGN--EGGLFRLEQD-GSLRTASRFNHNLQDEFVIQVRVFDNGTPP---LYSD 3587
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGS--NVGIGTSVGQIRVNDAFEQNDVSYDL 610
A V +++ + P I P E + S + G +G++ +D + +++++ L
Sbjct: 3588 AWVVVKIIE--ESQYPPIV----TPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSL 3641
Query: 611 LHG----YEEGVPFAVEERSGVITVVDDL 635
+ G Y+ F + +G I + +L
Sbjct: 3642 VSGPDDMYQSSKLFNISNNTGKIYAISNL 3670
Score = 36.7 bits (81), Expect = 4.9
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 1429 ERLSLNGL-TSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
E LN L T A D D G+N I+Y ++ E F I +G +R+ +L R+ +F
Sbjct: 3196 EDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLF 3255
>UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52;
Euteleostomi|Rep: Protocadherin-7 precursor - Homo
sapiens (Human)
Length = 1069
Score = 123 bits (297), Expect = 3e-26
Identities = 168/643 (26%), Positives = 266/643 (41%), Gaps = 75/643 (11%)
Query: 744 LDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE+RD Y +T+ + + S I +V I D NDN P FE + YE + ENS
Sbjct: 266 LDREQRDSYELTLRVRDGGDPPRSSQAILRVLI--TDVNDNSPRFEKSVYEADLAENSAP 323
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDSLDREKK 858
GT I ++A D D G N Y +FG E + +DE +G + + +DRE+
Sbjct: 324 GTPILQ---LRAADLDVGVNGQIEY-VFGAATESVRRLLRLDETSGWLSVL-HRIDREEV 378
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
+ +++ARD G + +A +++ I DENDN P IE RI + + A
Sbjct: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVP---SIEIRKIGRIPLKDGVANVAED 435
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
+++ D DQ EN + T++ G + ++
Sbjct: 436 VLVDTPIALVQVSDRDQ-------GENGVVTCTVV------------GDVPFQLK----- 471
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVF 1034
P S D K+YF+ H EF + I A+D G +L+ S+ V
Sbjct: 472 PASDTEGDQ-NKKKYFL------HTSTPLDYEATREFNVVIVAVDSGSPSLSSKNSLIVK 524
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V D ND+ P+F ++ E + V ATDAD G+NA + Y + S + F
Sbjct: 525 VGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGI-FA 583
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
I P +G + VN LDRE D+Y V A+D G D NDN PKF
Sbjct: 584 IDPDSGDILVNTVLDREQTDRYEFKVNAKDKG-IPVLQGSTTVIVQVADKNDNDPKF--M 640
Query: 1155 DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI 1214
++ + E + ++ V M+ V A NA + + + N+ I N G I
Sbjct: 641 QDVFTFYVKENLQPNS----PVGMVTVMDADKGRNAEMSLYIEE--NNNIFSIENDTGTI 694
Query: 1215 LYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
++ + Q G P S+TA + + V D D P IS Y L
Sbjct: 695 YSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNIS-YTLL 753
Query: 1265 EIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
NV V V ++ N + Y I+ N + F IDP +G + LV ++
Sbjct: 754 PPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF---KLFEIDPTSGVVSLVGKLTQK 810
Query: 1325 VKDTYEVIVRA-ERQKYSRELPHMIYPVAEDVLEGMTKYDVKV 1366
+ ++V+ + + S+ +++ + + T D ++
Sbjct: 811 HYGLHRLVVQVNDSGQPSQSTTTVVHVFVNESVSNATAIDSQI 853
Score = 95.1 bits (226), Expect = 1e-17
Identities = 122/470 (25%), Positives = 205/470 (43%), Gaps = 46/470 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + D NDN+P F S +YE + N+ GT I +++A D D+G NG + Y +
Sbjct: 294 LRVLITDVNDNSPRFEKS-VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATE 352
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQPANPSERRYSLAVVTIEVTRG 562
++ +++ +G +SV E + L V A D+ P + A V + + +
Sbjct: 353 -SVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDK---ATVVLNI-KD 407
Query: 563 TKGNKP--DIPDFMGAPYEFWVGS---NVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEE 616
N P +I P + V + +V + T + ++V+D + +N V + G
Sbjct: 408 ENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVG--- 464
Query: 617 GVPFAVEERSGVITVVDDLSRY---NRPMYDFEA--------VALQENA-NLSIVTNATV 664
VPF ++ S + + + P+ D+EA VA+ + +LS + V
Sbjct: 465 DVPFQLKPASDTEGDQNKKKYFLHTSTPL-DYEATREFNVVIVAVDSGSPSLSSKNSLIV 523
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V D ND + G ++ + N G + + T+ S G N +
Sbjct: 524 KVGDTNDNPPMF--GQSVVEVYFPENNIPGERVATVLATDADS--GK---NAEIAYSLDS 576
Query: 725 DVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
V AI D G I LDRE+ D Y V A+ +KG+ G V + + D+NDN
Sbjct: 577 SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK-DKGIPVLQGSTTVIVQVADKNDN 635
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F + ++ EN + + + M + DAD+G NA M E +F ++ +T
Sbjct: 636 DPKFMQDVFTFYVKENLQPNSPVGM---VTVMDADKGRNA-EMSLYIEENNNIFSIENDT 691
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
G + + S DRE + Y + A D G S+ A + + + DENDN P
Sbjct: 692 GTI-YSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAP 740
Score = 81.0 bits (191), Expect = 2e-13
Identities = 111/413 (26%), Positives = 173/413 (41%), Gaps = 56/413 (13%)
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
E+ +IV +L E + L + DGG+ + +RV + DVND+ P F+K+ Y
Sbjct: 255 EKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYE 314
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELD 1109
++ E + ++ A D D G N + Y + + + +G LSV +D
Sbjct: 315 ADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRID 374
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RE ++ TV+ARD G D NDN P + + + P D ++
Sbjct: 375 REEVNQLRFTVMARDRG-QPPKTDKATVVLNIKDENDNVP---SIEIRKIGRIPLKDGVA 430
Query: 1170 NHNFESVMMIPVYKATIE-----ENAPIGTTVAKVF------ANDTDFIGNGNGLILY-S 1217
N + ++ P+ + EN + TV A+DT+ N L+ S
Sbjct: 431 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 490
Query: 1218 LP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
P + + N+ G PSLSS L+V V D D + P+F E+
Sbjct: 491 TPLDYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTND-----NPPMFGQSVVEVYFP 545
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
EN N P E V+ L ++ K I D+ + F IDP +G + + DRE D
Sbjct: 546 EN-NIPGERVATVLATDADSGK-NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTD 603
Query: 1328 TYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
YE V A+ + +P VL+G T V+V++ D NDN PKF
Sbjct: 604 RYEFKVNAK----DKGIP---------VLQGST----TVIVQVADKNDNDPKF 639
Score = 81.0 bits (191), Expect = 2e-13
Identities = 49/160 (30%), Positives = 81/160 (50%), Gaps = 7/160 (4%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ T PLD E + + ++A + G S + + + + D NDNPP+F + E +
Sbjct: 487 LHTSTPLDYEATREFNVVIVA-VDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFP 545
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
EN+ G + + ATDAD G NA Y+L +F +D ++G + + LDRE+
Sbjct: 546 ENNIPGERVA---TVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDI-LVNTVLDREQ 601
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
Y+ + A+D G L +I+ + D+NDN P+F Q
Sbjct: 602 TDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ 641
Score = 80.2 bits (189), Expect = 4e-13
Identities = 106/464 (22%), Positives = 197/464 (42%), Gaps = 52/464 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAK-------VGTVIGKVKAVDPDLGQNGMVLY 497
V + + D NDN P + +K V T I V+ D D G+NG+V
Sbjct: 401 VVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVV-- 458
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
T + PF++ P + T + + F+ S + R +++ +V +
Sbjct: 459 ----TCTVVGDVPFQLKPASDTEGD------QNKKKYFLHTSTPLDYEATREFNVVIVAV 508
Query: 558 EV---TRGTK-------GNKPDIPDFMG-APYEFWVGSNVGIGTSVGQIRVNDAF--EQN 604
+ + +K G+ D P G + E + N G V + DA +
Sbjct: 509 DSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNA 568
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
+++Y L G+ FA++ SG I V L R Y+F+ A ++ + ++ +T
Sbjct: 569 EIAYSL-DSSVMGI-FAIDPDSGDILVNTVLDREQTDRYEFKVNA--KDKGIPVLQGSTT 624
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+V V D+ K F+VKEN + +G + T M + G ++ N
Sbjct: 625 VIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMV--TVMDADKGRNAEMSLYIEENN 682
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
+ + + GTI++ DRE + Y V A + G + V++++ DENDN
Sbjct: 683 NIFSIE---NDTGTIYSTMSFDREHQTTYTFRVKA-VDGGDPPRSATATVSLFVMDENDN 738
Query: 784 PPVF---EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDV 839
P ++ +Y + +S + T + + ATD+D+G NA Y++ G ++F++
Sbjct: 739 APTVTLPKNISYT-LLPPSSNVRTVVAT---VLATDSDDGINADLNYSIVGGNPFKLFEI 794
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
D +GVV +G L ++ +++L + D+G S ++ +
Sbjct: 795 DPTSGVVSLVG-KLTQKHYGLHRLVVQVNDSGQPSQSTTTVVHV 837
Score = 71.7 bits (168), Expect = 1e-10
Identities = 103/448 (22%), Positives = 184/448 (41%), Gaps = 58/448 (12%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
Q +++ L ++ +P +++QA + + + D+NDN P FE Y + EN G +LQ
Sbjct: 270 QRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQ 329
Query: 328 VMATDKDQGENGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ A D D G NG+ Y + + +D SGWL+V ++ +DRE + LR V A
Sbjct: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHR--IDREEVNQLRFTVMA 387
Query: 384 KETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFV 443
++ R QP +T +K T V + + +N+ + + + +
Sbjct: 388 RD------------------RGQPPKT----DKATVVL--NIKDENDNVPSIEIRKIGRI 423
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG----TVIGKV----KAVDPDLGQNGMV 495
++ + + ++ V P L + S + + G TV+G V K G
Sbjct: 424 PLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKK 483
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y L ++ L + + N V + SP L +++L V+ D NP S+ V
Sbjct: 484 KYFLHTSTPLDYEATREFNVVIVAVD-SGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEV 542
Query: 556 -----TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNV----GIGTSVGQIRVNDAF--EQN 604
I R D A + + S+V I G I VN EQ
Sbjct: 543 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQT 602
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
D ++ ++G+P + ++ V D + M D ++EN + N+ V
Sbjct: 603 DRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKEN----LQPNSPV 658
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENS 692
+V V D KG ++ + +++EN+
Sbjct: 659 GMVTVMDAD----KGRNAEMSLYIEENN 682
Score = 69.7 bits (163), Expect = 6e-10
Identities = 47/133 (35%), Positives = 65/133 (48%), Gaps = 6/133 (4%)
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
FL LD E + N ++ V + +P +++ + +++ D NDN P F +
Sbjct: 486 FLHTSTPLDYEATREFNVVIVAVDSG---SPSLSSKNSLIVKVGDTNDNPPMFGQSVVEV 542
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDRE 372
EN G V V+ATD D G+N E Y LD G F+IDP SG + V TVLDRE
Sbjct: 543 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILV--NTVLDRE 600
Query: 373 AHSSLRMKVYAKE 385
KV AK+
Sbjct: 601 QTDRYEFKVNAKD 613
Score = 66.5 bits (155), Expect = 5e-09
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 8/164 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G A + Y L S + +F++D +G + + LD + Q + + +V A
Sbjct: 559 ATDADSGKNAEIAYSLDS-SVMGIFAIDPDSGDILVNTVLDRE-----QTDRYEFKVNAK 612
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P+ V +++ D NDN P+F D + + ENL V V D D+G N
Sbjct: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNA 672
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
E + +++ FSI+ +G T+ + DRE ++ +V A
Sbjct: 673 EMSLYIEENNNIFSIENDTG--TIYSTMSFDREHQTTYTFRVKA 714
Score = 66.1 bits (154), Expect = 7e-09
Identities = 78/308 (25%), Positives = 127/308 (41%), Gaps = 28/308 (9%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
+V + +G +S+ S+ V + D NDN P+F + V E GE+ L
Sbjct: 505 IVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADS 564
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDK----PNT----PNSDVHYSIVSGNDDGHFALESSH 178
+ ++ I A D D NT +D + V+ D G L+ S
Sbjct: 565 GKNAEIAYSLDSSVM-GIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGS- 622
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP-EPIHAID-QDLGVGATLRYELI 236
++ +V D + D +F + KE L P P+ + D G L
Sbjct: 623 --TTVIVQVADKNDNDPKFMQDVFTF---YVKENLQPNSPVGMVTVMDADKGRNAEMSLY 677
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+ +FS+++ G+++ + D EH T+ +V+A +P ++A A V + +
Sbjct: 678 IEENNNIFSIENDTGTIY--STMSFDREHQ---TTYTFRVKAVDGGDPPRSATATVSLFV 732
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNG---FSVLQVMATDKDQGENGEFTYQL--DDPKGA 351
+D NDN P + NIS P+ V V+ATD D G N + Y + +P
Sbjct: 733 MDENDNAPTVTLP-KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKL 791
Query: 352 FSIDPRSG 359
F IDP SG
Sbjct: 792 FEIDPTSG 799
Score = 59.7 bits (138), Expect = 6e-07
Identities = 63/248 (25%), Positives = 109/248 (43%), Gaps = 22/248 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI-AN 722
V + DVND K + + ENSA I + + G + ++ A
Sbjct: 296 VLITDVNDNSPRFEKSVYEA---DLAENSAPGT--PILQLRAADLDVGVNGQIEYVFGAA 350
Query: 723 QQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ V + + E G + +DRE+ + R TV+A ++G V + I+DEN
Sbjct: 351 TESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMAR-DRGQPPKTDKATVVLNIKDEN 409
Query: 782 DNPPVFEHATYEGFIMEN--SKIGTEIKMDN---IIKATDADEGTNALFMYTLFGEG--- 833
DN P E +++ + + ++ +D +++ +D D+G N + T+ G+
Sbjct: 410 DNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQ 469
Query: 834 -KEMFDVDENTGVVKFI---GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDEN 887
K D + + K+ LD E + + +VA D+G LSS+ LI+ +GD N
Sbjct: 470 LKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTN 529
Query: 888 DNKPEFNQ 895
DN P F Q
Sbjct: 530 DNPPMFGQ 537
Score = 52.4 bits (120), Expect = 9e-05
Identities = 75/308 (24%), Positives = 134/308 (43%), Gaps = 28/308 (9%)
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKT-TYVFP 422
R TVL +A S ++ A + SV+G FA + N L++ T +
Sbjct: 553 RVATVLATDADSGKNAEI-AYSLDSSVMGIFAIDPDSGD-----ILVNTVLDREQTDRYE 606
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
KV K + I L V V + D NDN+P F+ +++ F +K N + + +G V
Sbjct: 607 FKVNAKDKGIPV----LQGSTTVIVQVADKNDNDPKFM-QDVFTFYVKENLQPNSPVGMV 661
Query: 483 KAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD 540
+D D G+N + ++ +N+ F I +TGT+ S E + + V+A D
Sbjct: 662 TVMDADKGRNAEMSLYIEENNNI-----FSIENDTGTIYSTMSFDREHQTTYTFRVKAVD 716
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
P R + A V++ V N P + Y S+ + T V + D+
Sbjct: 717 GGDPP---RSATATVSLFV-MDENDNAPTVTLPKNISYTLLPPSS-NVRTVVATVLATDS 771
Query: 601 FE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
+ D++Y ++ G + F ++ SGV+++V L++ + ++ V + ++ S
Sbjct: 772 DDGINADLNYSIVGGNPFKL-FEIDPTSGVVSLVGKLTQKHYGLHRL-VVQVNDSGQPSQ 829
Query: 659 VTNATVHV 666
T VHV
Sbjct: 830 STTTVVHV 837
Score = 52.0 bits (119), Expect = 1e-04
Identities = 82/364 (22%), Positives = 145/364 (39%), Gaps = 49/364 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D+GV + Y + + R+L LD +G L + +D + + N
Sbjct: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE-----EVNQLRFT 384
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN--------ISIVENLPNGFSVLQ 327
V A P KT +A V + + D NDN+P E+ ++ E++ +
Sbjct: 385 VMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIAL 444
Query: 328 VMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-K 384
V +D+DQGENG T + D P F + P S T +Q H+S + A +
Sbjct: 445 VQVSDRDQGENGVVTCTVVGDVP---FQLKPASD--TEGDQNKKKYFLHTSTPLDYEATR 499
Query: 385 ETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVN 444
E N +V + S ++ ++ T P G + + + +
Sbjct: 500 EFNVVIVAVDSGSPSLSSKNSLIVKVG-----DTNDNPPMFGQSVVEVYFPENNIPGERV 554
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V DA+ + +S+ S +V+G + A+DPD +G +L +
Sbjct: 555 ATVLATDADSGKNAEI-----AYSLDS-----SVMG-IFAIDPD---SGDILVNTVLDRE 600
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
T FK+N + P+L+G + V+ +D+ N ++ ++ V T V +
Sbjct: 601 QTDRYEFKVNAKDKGI-----PVLQGSTTVIVQVADK--NDNDPKFMQDVFTFYVKENLQ 653
Query: 565 GNKP 568
N P
Sbjct: 654 PNSP 657
Score = 45.2 bits (102), Expect = 0.014
Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGA 351
++ +LD+NDN P F +++ EN P G L ATD+D G NG Y+ L +P G
Sbjct: 130 QVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGG 189
Query: 352 FS 353
S
Sbjct: 190 GS 191
Score = 44.0 bits (99), Expect = 0.032
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+V +LD NDN P F PS + +++ N VGT+ A D D G+NG+ Y+L
Sbjct: 130 QVIVLDINDNTPTF-PSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 182
Score = 40.3 bits (90), Expect = 0.40
Identities = 21/42 (50%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 1441 ATDSDIGINADIRYQILNEQAPR-FAIDPVSGTVRVVAALAR 1481
ATDSD GINAD+ Y I+ + F IDP SG V +V L +
Sbjct: 768 ATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQ 809
Score = 39.5 bits (88), Expect = 0.69
Identities = 21/46 (45%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+LDRE++ Y+L+L RD G SS+A L ++I D NDN P F +
Sbjct: 265 ALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEK 310
Score = 36.7 bits (81), Expect = 4.9
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 1426 VFFERLSLNG--LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
V+F ++ G + + ATD+D G NA+I Y + + FAIDP SG + V L R+
Sbjct: 542 VYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
>UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenopus
tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
Length = 2689
Score = 122 bits (295), Expect = 6e-26
Identities = 141/558 (25%), Positives = 249/558 (44%), Gaps = 56/558 (10%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T T+ + + V V + + D NDN+P + +L S+ +A++G+++ ++ A D
Sbjct: 914 TATDQAANISHRRCTSVIVRIVIQDINDNSPQVL--SLPVASVMEDAQIGSLVHRIVAKD 971
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPA 543
PD G+NG + + ++ + + F ++ TG +++ S I ++ + L + A D
Sbjct: 972 PDEGRNGKIGFHIKEGNAQQV---FLLDETTGWLTL-HSEIDREVQDHYILTILALDDGI 1027
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
+L + I+V T P F YE V N G V ++ D
Sbjct: 1028 PSLSVTQTLTISLIDVNDKT-------PTFTQGLYEAAVPENQDPGLYVIKVAAVDYDLG 1080
Query: 604 ND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVT 660
N+ ++Y++L G G F + +G + R + + E + + LS T
Sbjct: 1081 NNSVLTYEILPGPAYG-HFRINPETGELVTTTVFDREQQDRFIIEVLVKDGGSPPLSSTT 1139
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFL 719
++D ND +L + V EN +G I HT +++ G G + F
Sbjct: 1140 AILCSILDENDHTPEVL---FPDVEIRVPENQD---LG-IIHTVLAADKDAGNNGRLHFQ 1192
Query: 720 IANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
I + ++ AI G ++ + LDRE + +TV + G + I ++ I +
Sbjct: 1193 ITDG-NMGGYFAINNTSGQLWATRTLDREDFSSFTITVECH-DLGTPHRSTIAKLRITVL 1250
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
DENDNPP F + Y + E+ KIG+ + ++A+DADEG N MY+L + + F
Sbjct: 1251 DENDNPPTFPKSQYRTLVREDLKIGSAVLK---LQASDADEGLNKEIMYSLIDDTQGAFT 1307
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFNQ 895
V+ TG + I +LDRE K Y +VA D S+ ++++ I D NDN P F +
Sbjct: 1308 VNRTTGNIVTI-RTLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTE 1366
Query: 896 -----------IEENSKVRIHR---ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-I 940
+E + +H + LNGT + +I+ N F + G + L +
Sbjct: 1367 NPIHVLISPKVLENKTIANVHASDVDLGLNGTVVYNLIK---SNPFFYITQEKGEVKLQM 1423
Query: 941 PENIPIGTTIIKLNALDL 958
P +T++++ A DL
Sbjct: 1424 PLPAEFSSTVLQVQASDL 1441
Score = 99.1 bits (236), Expect = 8e-19
Identities = 117/488 (23%), Positives = 201/488 (41%), Gaps = 38/488 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q ++ V V + D NDN PVF + F + T + +V A D D G NG + Y
Sbjct: 1547 QYTTYCRVTVFIQDDNDNAPVFDQLDYISF-VSEGQPFNTFVIQVFAADGDSGINGQIDY 1605
Query: 498 DLQRTSNLTITSPFKINPNTGTVS--VAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ + + F ++ G +S V ++ + L V+A+D+ +PS S +VV
Sbjct: 1606 SIISGNE---NNAFVLDSRHGILSTNVILDREIKSSYRLTVQATDR-GSPSCS--STSVV 1659
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
T+ + N P IP + + G S+G I ND + D+SY
Sbjct: 1660 TVLIL-DINDNAPTIPPMNTV----LIAEDAAPGYSIGSISANDVDLRPDLSYTFTENGN 1714
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
G+ FA++ SG+IT+ + L + A ++ + V+DVND V
Sbjct: 1715 PGLKFAIDRYSGIITLTESLDYEESSQHCLRIQA--SDSVYHTEAELIIKVLDVNDNPPV 1772
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNM-SSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ + + + E++ I + T+ S IYG T + I+ + + +
Sbjct: 1773 FTQNIYKVALPELTESN--TFITTVSATDQDSEIYGPITYKI---ISPLKGFVINTTSGK 1827
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+++T PL +E + +I + G +++ I D N+ P F Y
Sbjct: 1828 LRSVYTDMPLGKENKSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYV 1887
Query: 795 FIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVK------ 847
+ E++ +G + + A D D NAL +++ G E++ V+
Sbjct: 1888 NVSEDALVGDTVL---TLTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIV 1944
Query: 848 ----FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSK 901
I LD E ++L + + G L+S A +II I D NDN P F+ E +
Sbjct: 1945 TGKLIINQPLDFEVASAHRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVS 2004
Query: 902 VRIHRETK 909
VR H K
Sbjct: 2005 VREHYPLK 2012
Score = 98.7 bits (235), Expect = 1e-18
Identities = 121/458 (26%), Positives = 190/458 (41%), Gaps = 54/458 (11%)
Query: 936 PLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
P+ + E+ IG+ + ++ A D D G NG+I + +A +V F+++
Sbjct: 950 PVASVMEDAQIGSLVHRIVAKDPDEGRNGKIGFHIKE----------GNAQQV---FLLD 996
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
E G + + + E + + L I ALD G +L+ ++ + + DVND P F + Y
Sbjct: 997 ETTGWLTLHSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLIDVNDKTPTFTQGLYE 1056
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
V E Q + KV A D D G N+ LTY I P F I+P TG L DRE
Sbjct: 1057 AAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEILPGPAYGHFRINPETGELVTTTVFDRE 1116
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS-N 1170
+D++I+ V+ +D G D ND++P+ D +E + PE +L
Sbjct: 1117 QQDRFIIEVLVKDGG-SPPLSSTTAILCSILDENDHTPEVLFPD--VEIRVPENQDLGII 1173
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI----LYSLPQRKNQQN 1226
H + + G N+T + S +
Sbjct: 1174 HTVLAADKDAGNNGRLHFQITDGNMGGYFAINNTSGQLWATRTLDREDFSSFTITVECHD 1233
Query: 1227 LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE 1286
LG P S+ A L +TV D E + P F Y + E++ ++ L ++ E
Sbjct: 1234 LGTPHRSTIAKLRITVLD-----ENDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADE 1288
Query: 1287 --NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
N ++ Y +++ D + F ++ G + +R+ DREVK Y V
Sbjct: 1289 GLNKEIMYSLID----DTQGAFTVNRTTGNIVTIRTLDREVKHQYVFRV----------- 1333
Query: 1345 PHMIYPVAEDV-LEGMTKYDVKVVVRIKDVNDNSPKFT 1381
VA D L VKV+V I+DVNDNSP FT
Sbjct: 1334 ------VASDCSLRNPKSATVKVLVYIEDVNDNSPVFT 1365
Score = 97.1 bits (231), Expect = 3e-18
Identities = 123/461 (26%), Positives = 209/461 (45%), Gaps = 38/461 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN PVF PS Y S+ S+ + GT I V A+D D G G V Y+L +
Sbjct: 75 VRVDIEDINDNAPVFEPST-YVTSISSHTQPGTEILNVMAIDRDEGLFGDVTYELLSGEH 133
Query: 505 LTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+S F I+ +TG + + S + + +L V A D+ S A VT+ + +
Sbjct: 134 ---SSLFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLTSAVN---ATVTMNILK- 186
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-NDVSYDLLHGYEEGVPFA 621
P I F + Y F + +V G++VG ++ + VSY ++ G + F
Sbjct: 187 -TATAPAI--FEKSRYTFVIAEDVPKGSAVGTVKAREPLNSLEPVSYRIISGNVHQM-FT 242
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ + G+I +L + P+ + ++++ T V + D ND V +
Sbjct: 243 IHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDNPPV-FSSEN 301
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIAEDGTIFT 740
I H + S G AI T++ S + G + + IA++ QD+ I + G ++
Sbjct: 302 ERISVH-QNTSPGTAIYIAQATDLDSGF---NGQISYSIASENQDLF--IIDSTFGVLYL 355
Query: 741 QKPLDREKRDVYRMTVIAE-FNKGVISGAGIYQVTIYIE-DENDNPPVFEHATYEGFIME 798
L + V + ++AE + VIS + +TI +E ++ N F + + I E
Sbjct: 356 NATLSSVREHV--LLILAEDYGHPVIS--SLLTLTIIVEQNKQSNTLSFFNLVHRTEISE 411
Query: 799 NSKIGTEIKMDNIIKA-TDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFIGDSLDRE 856
I + I +KA T + T++ MY+L F + ++TG + F+ S+D E
Sbjct: 412 TLPINSHILQ---VKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTGWI-FLRRSVDYE 467
Query: 857 KKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEFN 894
K + L +VA ++ A +I+ I DENDN P F+
Sbjct: 468 KSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFD 508
Score = 95.9 bits (228), Expect = 8e-18
Identities = 103/413 (24%), Positives = 185/413 (44%), Gaps = 35/413 (8%)
Query: 481 KVKAVDPDLGQNGMVLYDL-QRTSNLTITSPFKINPNTGTVSVAESPILEG---RHALFV 536
KVKA D D G G + Y + N + F+I+P++G + V+ E + L V
Sbjct: 2 KVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLLV 61
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
+A D+ ++ A V +++ + + P F + Y + S+ GT + +
Sbjct: 62 KAEDEGGLSAQ-----AFVRVDI----EDINDNAPVFEPSTYVTSISSHTQPGTEILNVM 112
Query: 597 VNDAFEQ--NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA 654
D E DV+Y+LL G E F ++ +G+I ++ LS +VA ++
Sbjct: 113 AIDRDEGLFGDVTYELLSG-EHSSLFTIDSSTGIIYLISVLSHLEDSWVSL-SVAARDKG 170
Query: 655 NLSIVTNATV--HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG 712
L+ NATV +++ + K ++ +I ++ G+A+G + +
Sbjct: 171 GLTSAVNATVTMNILKTATAPAIFEKSRYTFVI--AEDVPKGSAVGTV--KAREPLNSLE 226
Query: 713 TGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ 772
+ R + N + + G I TQK LD E + +TV ++ + + Q
Sbjct: 227 PVSYRIISGNVHQMF--TIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSS--TQ 282
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V + I D NDNPPVF + +N+ GT I I +ATD D G N Y++ E
Sbjct: 283 VNVTITDANDNPPVFSSENERISVHQNTSPGTAI---YIAQATDLDSGFNGQISYSIASE 339
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMI 883
+++F +D GV+ ++ +L ++ + L ++A D G +SS L I++
Sbjct: 340 NQDLFIIDSTFGVL-YLNATLSSVRE--HVLLILAEDYGHPVISSLLTLTIIV 389
Score = 93.1 bits (221), Expect = 5e-17
Identities = 94/354 (26%), Positives = 154/354 (43%), Gaps = 28/354 (7%)
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVS 607
+L+V T ++P PD + V +V +GT + + ND + E + +
Sbjct: 817 NLSVFLTIYIEDTNDHRPLFPDHI---IVLGVDEDVPVGTLLYTFKANDKDGSLENSKIR 873
Query: 608 YDL-LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS--IVTNATV 664
Y L HG E PF + E G +T ++L R + A + AN+S T+ V
Sbjct: 874 YSLNTHGTGEN-PFFIHEWEGALTTANELDREMAESFVLTVTATDQAANISHRRCTSVIV 932
Query: 665 HVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIA 721
+V D+ND +L S + V E+ A IG + H ++ G G + F I
Sbjct: 933 RIVIQDINDNSPQVL----SLPVASVMED---AQIGSLVHRIVAKDPDEGRNGKIGFHIK 985
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ G + +DRE +D Y +T++A + G+ S + +TI + D N
Sbjct: 986 EGNAQQVFLLDETTGWLTLHSEIDREVQDHYILTILA-LDDGIPSLSVTQTLTISLIDVN 1044
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD 840
D P F YE + EN G + + A D D G N++ Y + G F ++
Sbjct: 1045 DKTPTFTQGLYEAAVPENQDPGLYVIK---VAAVDYDLGNNSVLTYEILPGPAYGHFRIN 1101
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
TG + DRE++ + + ++ +D G LSS ++ I DEND+ PE
Sbjct: 1102 PETGEL-VTTTVFDREQQDRFIIEVLVKDGGSPPLSSTTAILCSILDENDHTPE 1154
Score = 88.6 bits (210), Expect = 1e-15
Identities = 107/454 (23%), Positives = 192/454 (42%), Gaps = 36/454 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
++ + G+ +S ++T+ + DVND P F Y V E G ++ +A +
Sbjct: 1020 ILALDDGIPSLSVTQTLTISLIDVNDKTPTFTQGLYEAAVPENQDPG--LYVIKVAAVDY 1077
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK----PVL 182
L + + F R P T V ++ F +E K P L
Sbjct: 1078 DLGNNSVLTYEILPGPAYGHF-RINPETGEL-VTTTVFDREQQDRFIIEVLVKDGGSPPL 1135
Query: 183 -----LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
+L +LD + E + ++++ + A D+D G L +++
Sbjct: 1136 SSTTAILCSILDENDHTPEVLFPDVEIRVPENQDLGIIHTVLAADKDAGNNGRLHFQITD 1195
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN F++++ +G L+ + LD + ++F + V+ L P ++ A++ I +L
Sbjct: 1196 GNMGGYFAINNTSGQLWATRTLDRE-----DFSSFTITVECHDLGTPHRSTIAKLRITVL 1250
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDP 356
D NDN P F Y + E+L G +VL++ A+D D+G N E Y L DD +GAF+++
Sbjct: 1251 DENDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSLIDDTQGAFTVNR 1310
Query: 357 RSG-WLTVRNQTVLDREAHSSLRMKVYAKE---TNP--SVVGTFADSQRIAKWRRQPLET 410
+G +T+R LDRE +V A + NP + V + + P+ T
Sbjct: 1311 TTGNIVTIR---TLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVND--NSPVFT 1365
Query: 411 NAPLEKTTYVFPDKVGTKT-ENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSM 469
P+ + P + KT N+ D L V L+ +N + + M
Sbjct: 1366 ENPIH--VLISPKVLENKTIANVHASDVDLGLNGTVVYNLIKSNPFFYITQEKGEVKLQM 1423
Query: 470 KSNAKVGTVIGKVKAVDPDLGQN---GMVLYDLQ 500
A+ + + +V+A D + N G+V+ D+Q
Sbjct: 1424 PLPAEFSSTVLQVQASDLGIPPNTVTGLVIIDIQ 1457
Score = 87.0 bits (206), Expect = 3e-15
Identities = 185/796 (23%), Positives = 324/796 (40%), Gaps = 90/796 (11%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
I A +Q + Y VTV+I+D NDN P+F Y V E P F+ +
Sbjct: 1541 ISAESSQYTTYCRVTVFIQDDNDNAPVFDQLDYISFVSEGQPFN--TFVIQVFAADGDSG 1598
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPN---TPNSDVHYSI-------VSGNDDGHFALESSHK 179
I + + + AF D + + N + I V D G + S+
Sbjct: 1599 INGQIDYSIISGNENNAFVLDSRHGILSTNVILDREIKSSYRLTVQATDRGSPSCSSTSV 1658
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN 239
+L+ + D V++A I I A D DL + + +GN
Sbjct: 1659 VTVLILDINDNAPTIPPMNTVLIAEDAAPGYSI---GSISANDVDLRPDLSYTFTE-NGN 1714
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
F++D +G + L + LD + +++ L++QAS + + +A + I++LD+
Sbjct: 1715 PGLKFAIDRYSGIITLTESLDYE-----ESSQHCLRIQAS---DSVYHTEAELIIKVLDV 1766
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
NDN P F + Y +++ E + + V ATD+D G TY++ P F I+ SG
Sbjct: 1767 NDNPPVFTQNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKIISPLKGFVINTTSG 1826
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTY 419
L R ++ + + K T ++ D+ PL + A L T
Sbjct: 1827 KL---------RSVYTDMPLGKENKSTEIQILIVAMDN------GSPPLTSTAMLSVTIL 1871
Query: 420 VFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSN-LYEFSMKSNAKVGTV 478
+ T +E+I Y + + V V L A D + + P N L +FS+
Sbjct: 1872 DVNNYAPTFSEDIYYVNVSEDALVGDTVLTLTAMDLD--WSPKNALIDFSI--------- 1920
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFV 536
+G N L+ L+ +S + PF + TG + + + E H L +
Sbjct: 1921 ----------IGGNAHNLFYLE-SSEVLSHIPFIV---TGKLIINQPLDFEVASAHRLDI 1966
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
S+Q P S A + I + + P P F + Y V + + +++ I
Sbjct: 1967 FVSNQGFPPLN---SSATIIINIL--DSNDNP--PLFSNSEYHVSVREHYPLKSTIIIIS 2019
Query: 597 V--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA 654
+D E D++Y ++ G +E V F ++ ++G +T+V L Y A +
Sbjct: 2020 ATDSDTGENADITYSIVSGNDENV-FTIDAQNGTVTLVQPLDYEETMKYSLTLQARDGHG 2078
Query: 655 NLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIF-HVKENSAGAAIGQIFHTNMSSIYGN 711
+ V A ++ V+D ND L + S I+ +V S ++ I S YG
Sbjct: 2079 SKRNVAFALLSITVLDENDFAPKFLFQSQSCNIYENVPFFSPVCSVNAI--DLDSGQYGI 2136
Query: 712 GTGNVRFLIAN-QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
+ +++ N QQ + + G I+T+ +D E ++ R ++ + S A +
Sbjct: 2137 LSFSIQSSCFNDQQHPATFLIDSLTGDIYTKHRIDYEMQE--RHCLVVQVKDRSESSACV 2194
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
V I IE E++ PVF Y + E + G EI + A D DEG + + Y L
Sbjct: 2195 L-VYIDIEGEDEFQPVFYQNQYLFDLPEENIGGQEI---GKVGALDNDEGLDGVVHYFL- 2249
Query: 831 GEGKEMFDVDENTGVV 846
+ + F ++ +G++
Sbjct: 2250 EKPSQFFSINMTSGMI 2265
Score = 84.6 bits (200), Expect = 2e-14
Identities = 84/318 (26%), Positives = 135/318 (42%), Gaps = 25/318 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI---------APIGPSLTIPLT 133
+T+YIED ND+ P+F D + VDE P G + F + I SL T
Sbjct: 822 LTIYIEDTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLENSKIRYSLNTHGT 881
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL-LLRKVLDYDA 192
I + A N + ++ S V A SH+ ++ +++ D
Sbjct: 882 GENPFFIHEWEGALTT--ANELDREMAESFVLTVTATDQAANISHRRCTSVIVRIVIQDI 939
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSV 249
D Q++ + + ++ +H I D D G + + + GN +++F LD
Sbjct: 940 NDNSPQVLSLPVAS-VMEDAQIGSLVHRIVAKDPDEGRNGKIGFHIKEGNAQQVFLLDET 998
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G L L E+D + + + ++L + A P + + I L+D+ND P F
Sbjct: 999 TGWLTLHSEIDREVQDH-----YILTILALDDGIPSLSVTQTLTISLIDVNDKTPTFTQG 1053
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPK-GAFSIDPRSGWLTVRNQT 367
Y ++ EN G V++V A D D G N TY+ L P G F I+P +G L T
Sbjct: 1054 LYEAAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEILPGPAYGHFRINPETGELV--TTT 1111
Query: 368 VLDREAHSSLRMKVYAKE 385
V DRE ++V K+
Sbjct: 1112 VFDREQQDRFIIEVLVKD 1129
Score = 83.4 bits (197), Expect = 4e-14
Identities = 100/372 (26%), Positives = 158/372 (42%), Gaps = 40/372 (10%)
Query: 987 EVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLND-NISV--RVFVKDVNDH 1041
E K +FV++ G V V+R L E S + L+I + ++ N+SV ++++D NDH
Sbjct: 773 ENKGHFVVDSLTGDVYVSRHLDFETISYYGLSIDIQEIDKISPPNLSVFLTIYIEDTNDH 832
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDT-DLPFEISPLT 1099
P+F V+E +L A D D +N+ + Y + T + PF I
Sbjct: 833 RPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLENSKIRYSLNTHGTGENPFFIHEWE 892
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNGXXXXXX--XXXXXXXXXXDVNDNSPKFYAFDEL 1157
G L+ ELDRE + ++LTV A D D+NDNSP+ +
Sbjct: 893 GALTTANELDREMAESFVLTVTATDQAANISHRRCTSVIVRIVIQDINDNSPQVLSL--- 949
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIE-ENAPIGTTVAKVFANDTDFIGNGNG-LIL 1215
P A + + S++ V K E N IG + + A + G L L
Sbjct: 950 -----PVASVMEDAQIGSLVHRIVAKDPDEGRNGKIGFHIKEGNAQQVFLLDETTGWLTL 1004
Query: 1216 YSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEI 1266
+S R+ Q + G+PSLS T L +++ DV D+ P F YE +
Sbjct: 1005 HSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLIDVNDKT-----PTFTQGLYEAAV 1059
Query: 1267 EENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
EN + + ++ + ++ N + Y IL F I+P G L DRE
Sbjct: 1060 PENQDPGLYVIKVAAVDYDLGNNSVLTYEIL---PGPAYGHFRINPETGELVTTTVFDRE 1116
Query: 1325 VKDTY--EVIVR 1334
+D + EV+V+
Sbjct: 1117 QQDRFIIEVLVK 1128
Score = 83.4 bits (197), Expect = 4e-14
Identities = 61/191 (31%), Positives = 90/191 (47%), Gaps = 11/191 (5%)
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
SI G N+ +L +V I G + +PLD E +R+ + N+G
Sbjct: 1919 SIIGGNAHNLFYL--ESSEVLSHIPFIVTGKLIINQPLDFEVASAHRLDIFVS-NQGFPP 1975
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+ I I D NDNPP+F ++ Y + E+ + + I II ATD+D G NA
Sbjct: 1976 LNSSATIIINILDSNDNPPLFSNSEYHVSVREHYPLKSTI---IIISATDSDTGENADIT 2032
Query: 827 YTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE---AELIIM 882
Y++ G + +F +D G V + LD E+ + Y L+L ARD G A L I
Sbjct: 2033 YSIVSGNDENVFTIDAQNGTVTLV-QPLDYEETMKYSLTLQARDGHGSKRNVAFALLSIT 2091
Query: 883 IGDENDNKPEF 893
+ DEND P+F
Sbjct: 2092 VLDENDFAPKF 2102
Score = 81.4 bits (192), Expect = 2e-13
Identities = 115/475 (24%), Positives = 186/475 (39%), Gaps = 34/475 (7%)
Query: 439 LMSFVNVEVTL-LDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L S VN VT+ + P + Y F + + G+ +G VKA +P L V Y
Sbjct: 172 LTSAVNATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREP-LNSLEPVSY 230
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
R + + F I+ G + + E + + Q + S +S V +
Sbjct: 231 ---RIISGNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSV--FSSTQVNV 285
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV--GQIRVNDAFEQNDVSYDLLHGYE 615
+T + P P F V N GT++ Q D+ +SY + +
Sbjct: 286 TITDAN--DNP--PVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQ 341
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ F ++ GV+ + LS + A S++T T+ +V+ N +
Sbjct: 342 D--LFIIDSTFGVLYLNATLSSVREHVLLILAEDYGHPVISSLLT-LTI-IVEQNKQSNT 397
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI--- 732
L + ++ H E S I H Y T + I T D A
Sbjct: 398 L---SFFNLV-HRTEISETLPINS--HILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRI 451
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G IF ++ +D EK + + V+A + + I DENDN P F+HAT
Sbjct: 452 HQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHAT 511
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ F + S + + I+A D D G N Y L EG F + TG +
Sbjct: 512 HF-FTVNESPVPHGVI--GSIQAFDRDSGNNGQLSYFLLSEGNN-FLISSKTGEIINCA- 566
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDNKPEFNQIEENSKVRI 904
SLDRE+K ++L+++ D G A + I++ D NDNKP F Q+ ++ +
Sbjct: 567 SLDRERKAHHELNVLVTDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLHV 621
Score = 81.4 bits (192), Expect = 2e-13
Identities = 131/532 (24%), Positives = 215/532 (40%), Gaps = 56/532 (10%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
++Q + ++ V +LD NDN+P F + + F++ + VIG ++A D D G NG +
Sbjct: 484 EDQQTATASIIVKILDENDNSPSFDHATHF-FTVNESPVPHGVIGSIQAFDRDSGNNGQL 542
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
Y L N F I+ TG + S E + H L V +D N + RR +
Sbjct: 543 SYFLLSEGN-----NFLISSKTGEIINCASLDRERKAHHELNVLVTD---NGTPRRNATT 594
Query: 554 VVTIEVTRGTKGNKPDIPDFM-GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V I + NKP P G V V + D N+ +
Sbjct: 595 TVYI-IVADLNDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFF 653
Query: 613 GYEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVA-------LQENANLSIVTNATV 664
+E F + +G I L+ RP Y A L E+ ++I T
Sbjct: 654 ASDESFGQFVINASTGEIWTTKALTAKLRPQYGLTVTASDQGTPPLVEHTVVNIEITITA 713
Query: 665 HVVDVNDERGVLLKGAHSPII--FHVKENSAGAA-IGQIFHTNMSSIYGNGTGNVRFLIA 721
V+ + K I V EN+ IG + + + + + + +A
Sbjct: 714 EVLQHPPKVSFKEKTKTVSKIKTMKVPENTYPTQKIGSVISHEEAFLLSS---KMHYRLA 770
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDE 780
N+++ + + G ++ + LD E Y +++ I E +K ++ +TIYIED
Sbjct: 771 NEENKGHFVVDSLTGDVYVSRHLDFETISYYGLSIDIQEIDKISPPNLSVF-LTIYIEDT 829
Query: 781 NDNPPVF-EHATYEGFIMENSKIGTEIKMDNIIKATDADEG-TNALFMYTL--FGEGKEM 836
ND+ P+F +H G + E+ +GT + KA D D N+ Y+L G G+
Sbjct: 830 NDHRPLFPDHIIVLG-VDEDVPVGTLL---YTFKANDKDGSLENSKIRYSLNTHGTGENP 885
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE-----LIIMIGDENDNKP 891
F + E G + + LDRE + L++ A D S + I+I D NDN P
Sbjct: 886 FFIHEWEGALT-TANELDREMAESFVLTVTATDQAANISHRRCTSVIVRIVIQDINDNSP 944
Query: 892 E-----FNQIEENSKV--RIHR------ETKLNGTAGFTIIEVKPKNKFALD 930
+ + E++++ +HR + NG GF I E + F LD
Sbjct: 945 QVLSLPVASVMEDAQIGSLVHRIVAKDPDEGRNGKIGFHIKEGNAQQVFLLD 996
Score = 79.4 bits (187), Expect = 7e-13
Identities = 109/467 (23%), Positives = 188/467 (40%), Gaps = 37/467 (7%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L S + ++LD ND+ P V P E + N +G +I V A D D G NG + +
Sbjct: 1135 LSSTTAILCSILDENDHTPEVLFPD--VEIRVPENQDLG-IIHTVLAADKDAGNNGRLHF 1191
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ ++ + F IN +G + + E + + R + +
Sbjct: 1192 QI---TDGNMGGYFAINNTSGQLWATRTLDREDFSSFTITVECHDLGTPHRS---TIAKL 1245
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYE 615
+T + + P P F + Y V ++ IG++V +++ +DA E ++ Y L+ +
Sbjct: 1246 RITVLDENDNP--PTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSLIDDTQ 1303
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDER 673
F V +G I + L R + Y F VA + S V++ DVND
Sbjct: 1304 GA--FTVNRTTGNIVTIRTLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVNDNS 1361
Query: 674 GVLLKGA-HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V + H I V EN A + H + + NGT + +N
Sbjct: 1362 PVFTENPIHVLISPKVLENKTIANV----HASDVDLGLNGTVVYNLIKSNPFFYITQ--- 1414
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E G + Q PL E ++ + G+ + I D F H Y
Sbjct: 1415 -EKGEVKLQMPLPAEFSSTVLQVQASDLGIPPNTVTGLVIIDI---QGLDKEIAFVHNFY 1470
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
E I+ENS+ GT + + DE + YT+F G+ K F+++ TG +
Sbjct: 1471 EAIILENSEAGTLVVTVKALYHNPNDE----IIHYTVFSGDKKGAFNLNPITGDLMVKEP 1526
Query: 852 SL-DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
L D E + L +++ ++ ++ + + I D+NDN P F+Q++
Sbjct: 1527 RLLDFETVNKFNL-IISAESSQYTTYCRVTVFIQDDNDNAPVFDQLD 1572
Score = 78.6 bits (185), Expect = 1e-12
Identities = 109/443 (24%), Positives = 176/443 (39%), Gaps = 57/443 (12%)
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS-GLNGQIRYEFNSEVY 975
TII + K L L I E +PI + I+++ A ++ + +I Y + +
Sbjct: 386 TIIVEQNKQSNTLSFFNLVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTID 445
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL-DGGNLNDN----IS 1030
P F I++ G + + RS+ E N+ + G+ D S
Sbjct: 446 SAP-------------FRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQQTATAS 492
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
+ V + D ND+ P F + F V E+ V+G + A D D G N L+YF+ +
Sbjct: 493 IIVKILDENDNSPSFDHATHFFTVNESPVPHGVIGSIQAFDRDSGNNGQLSYFLLSEGNN 552
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F IS TG + LDRE + + L V+ DNG D+NDN P
Sbjct: 553 --FLISSKTGEIINCASLDRERKAHHELNVLVTDNG-TPRRNATTTVYIIVADLNDNKP- 608
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---- 1206
F +L K ++ E +++ VY + +A TV FA+D F
Sbjct: 609 --YFPQLASGKQLHV-KVMEGQAEPMLVATVYAK--DPDAGNNGTVVYFFASDESFGQFV 663
Query: 1207 -------IGNGNGLILYSLPQ---RKNQQNLGLPSLSSTAILMVTV---ADV---PDEVE 1250
I L PQ + G P L ++ + + A+V P +V
Sbjct: 664 INASTGEIWTTKALTAKLRPQYGLTVTASDQGTPPLVEHTVVNIEITITAEVLQHPPKVS 723
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF----KMRYYILNENDTDIRRTF 1306
+K +S+ +++ EN P + + ++ H E F KM Y + NE + + F
Sbjct: 724 FKEKTKTVSKIKTMKVPEN-TYPTQKIG-SVISHEEAFLLSSKMHYRLANEEN---KGHF 778
Query: 1307 VIDPRNGTLYLVRSPDREVKDTY 1329
V+D G +Y+ R D E Y
Sbjct: 779 VVDSLTGDVYVSRHLDFETISYY 801
Score = 78.2 bits (184), Expect = 2e-12
Identities = 85/344 (24%), Positives = 148/344 (43%), Gaps = 37/344 (10%)
Query: 47 DSPQNVVKFRLGCDFDEGDD-LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVT 105
D ++ D++E +RI A + + + + DVNDN P+F Y V
Sbjct: 1722 DRYSGIITLTESLDYEESSQHCLRIQASDSVYHTEAELIIKVLDVNDNPPVFTQNIYKVA 1781
Query: 106 VDELTPTGEKAFIFLIAPIGPSLTI--PLTVP-----RGLTIFKD---IRAFDRDKP--- 152
+ ELT + FI ++ I P+T +G I +R+ D P
Sbjct: 1782 LPELTESN--TFITTVSATDQDSEIYGPITYKIISPLKGFVINTTSGKLRSVYTDMPLGK 1839
Query: 153 NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI 212
++++ IV+ D+G L S+ + + V +Y E + S + +
Sbjct: 1840 ENKSTEIQILIVA-MDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYVNVSEDALVGDT 1898
Query: 213 LFPEPIHAIDQDLGV-GATLRYELISGNDRKLFSLDS----------VNGSLFLEKELDL 261
+ + A+D D A + + +I GN LF L+S V G L + + LD
Sbjct: 1899 VLT--LTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIVTGKLIINQPLDF 1956
Query: 262 DAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN 321
+ A+ L + S P + A + I +LD NDN P F Y++S+ E+ P
Sbjct: 1957 EV-----ASAHRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSVREHYPL 2011
Query: 322 GFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTV 363
+++ + ATD D GEN + TY + + + F+ID ++G +T+
Sbjct: 2012 KSTIIIISATDSDTGENADITYSIVSGNDENVFTIDAQNGTVTL 2055
Score = 77.8 bits (183), Expect = 2e-12
Identities = 102/396 (25%), Positives = 169/396 (42%), Gaps = 47/396 (11%)
Query: 921 VKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
++ N A DQL + + E P T +I++ A D DSG+NGQI Y S
Sbjct: 1558 IQDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDY----------SI 1607
Query: 981 LSADALEVKRYFVINERHG----HVIVARSLPPESEFRLNISALDGG--NLNDNISVRVF 1034
+S + FV++ RHG +VI+ R + +S +RL + A D G + + V V
Sbjct: 1608 ISGNE---NNAFVLDSRHGILSTNVILDREI--KSSYRLTVQATDRGSPSCSSTSVVTVL 1662
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ D+ND+ P E+A +G + A D D + + T F + + L F
Sbjct: 1663 ILDINDNAPTIPPMNTVLIAEDAA-PGYSIGSISANDVDLRPDLSYT-FTENGNPGLKFA 1720
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--- 1151
I +G++++ LD E ++ L + A D+ DVNDN P F
Sbjct: 1721 IDRYSGIITLTESLDYEESSQHCLRIQASDS----VYHTEAELIIKVLDVNDNPPVFTQN 1776
Query: 1152 ---YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE--ENAPIGTTVAKVFANDTDF 1206
A EL E + +S + +S + P+ I + I TT K+ + TD
Sbjct: 1777 IYKVALPELTE-SNTFITTVSATDQDSEIYGPITYKIISPLKGFVINTTSGKLRSVYTDM 1835
Query: 1207 -IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+G N + + G P L+STA+L VT+ DV + P F Y +
Sbjct: 1836 PLGKENKST--EIQILIVAMDNGSPPLTSTAMLSVTILDVNNYA-----PTFSEDIYYVN 1888
Query: 1266 IEENV---NAPVELVSLNLTEHYENFKMRYYILNEN 1298
+ E+ + + L +++L +N + + I+ N
Sbjct: 1889 VSEDALVGDTVLTLTAMDLDWSPKNALIDFSIIGGN 1924
Score = 77.4 bits (182), Expect = 3e-12
Identities = 102/439 (23%), Positives = 181/439 (41%), Gaps = 26/439 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ S V VT+ DANDN PVF N S+ N GT I +A D D G NG + Y
Sbjct: 277 VFSSTQVNVTITDANDNPPVFSSEN-ERISVHQNTSPGTAIYIAQATDLDSGFNGQISYS 335
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + N + F I+ G + + + H L + A D +P SL +TI
Sbjct: 336 I-ASENQDL---FIIDSTFGVLYLNATLSSVREHVLLILAEDY-GHPVIS--SLLTLTII 388
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV---NDAFEQNDVSYDLLHGYE 615
V + + N F + + + I + + Q++ N +++ Y L
Sbjct: 389 VEQNKQSN---TLSFFNLVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTI- 444
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ PF + + +G I + + ++ + VA + A++ +V + DE
Sbjct: 445 DSAPFRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQQTATASI-IVKILDENDN 503
Query: 676 LLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
H+ F V E+ IG I + S GN G + + + ++ + + + ++
Sbjct: 504 SPSFDHATHFFTVNESPVPHGVIGSIQAFDRDS--GN-NGQLSYFLLSEGN--NFLISSK 558
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-EHATYE 793
G I LDRE++ + + V+ N G V I + D NDN P F + A+ +
Sbjct: 559 TGEIINCASLDRERKAHHELNVLVTDN-GTPRRNATTTVYIIVADLNDNKPYFPQLASGK 617
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDS 852
++ + E + + A D D G N +Y E F ++ +TG + + +
Sbjct: 618 QLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFFASDESFGQFVINASTGEI-WTTKA 676
Query: 853 LDREKKIMYKLSLVARDTG 871
L + + Y L++ A D G
Sbjct: 677 LTAKLRPQYGLTVTASDQG 695
Score = 77.4 bits (182), Expect = 3e-12
Identities = 66/235 (28%), Positives = 107/235 (45%), Gaps = 15/235 (6%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSK 980
LDV+ P F + E+ +G T++ L A+DLD S N I +
Sbjct: 1871 LDVNNYAPTFSEDIYYVNVSEDALVGDTVLTLTAMDLDWSPKNALIDFSIIGGNAHNLFY 1930
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVK 1036
L + + F++ G +I+ + L E S RL+I + G LN + ++ + +
Sbjct: 1931 LESSEVLSHIPFIVT---GKLIINQPLDFEVASAHRLDIFVSNQGFPPLNSSATIIINIL 1987
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
D ND+ P+F + Y+ +V E + + + ATD+D G+NA++TY I + + F I
Sbjct: 1988 DSNDNPPLFSNSEYHVSVREHYPLKSTIIIISATDSDTGENADITYSIVSGNDENVFTID 2047
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
G +++ LD E KY LT+ ARD D ND +PKF
Sbjct: 2048 AQNGTVTLVQPLDYEETMKYSLTLQARDGHGSKRNVAFALLSITVLDENDFAPKF 2102
Score = 72.9 bits (171), Expect = 6e-11
Identities = 53/166 (31%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y + SG+ + F+L+ + G L +++ LD E + N ++ ++SQ T
Sbjct: 1499 IHYTVFSGDKKGAFNLNPITGDLMVKEPRLLDFETVNKFN-LIISAESSQY-----TTYC 1552
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDP 348
RV + + D NDN P F+ Y + E P V+QV A D D G NG+ Y + +
Sbjct: 1553 RVTVFIQDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSIISGNE 1612
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
AF +D R G L+ +LDRE SS R+ V A + +PS T
Sbjct: 1613 NNAFVLDSRHGILS--TNVILDREIKSSYRLTVQATDRGSPSCSST 1656
Score = 71.3 bits (167), Expect = 2e-10
Identities = 95/379 (25%), Positives = 150/379 (39%), Gaps = 36/379 (9%)
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE 1010
IK+ A D DSG GQI Y + S F I+ G + V+ + E
Sbjct: 1 IKVKATDADSGPFGQIHYSVYDGFHNTKESQS---------FRIDPDSGRICVSNDIDKE 51
Query: 1011 S---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
S + L + A D G L+ VRV ++D+ND+ PVF+ + Y ++ + V
Sbjct: 52 SGPTSYDLLVKAEDEGGLSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNV 111
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI-LTVVARDNG 1126
A D D G ++TY + + F I TG++ + L ED ++ L+V ARD G
Sbjct: 112 MAIDRDEGLFGDVTYELLSGEHSSLFTIDSSTGIIYLISVLS-HLEDSWVSLSVAARDKG 170
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI--PVYKA 1184
+P + E + A+++ + + P+
Sbjct: 171 GLTSAVNATVTMNILKTA--TAPAIF---EKSRYTFVIAEDVPKGSAVGTVKAREPLNSL 225
Query: 1185 TIEENAPIGTTVAKVFANDTDF--IGNGNGLILYSLP--QRKNQQNLGLPSLSSTAILMV 1240
I V ++F T F I L SLP Q LG S+ S+ + V
Sbjct: 226 EPVSYRIISGNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNV 285
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYYILNEN 1298
T+ D D + PVF S + + +N + + T+ F ++ Y I +EN
Sbjct: 286 TITDAND-----NPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASEN 340
Query: 1299 DTDIRRTFVIDPRNGTLYL 1317
D+ F+ID G LYL
Sbjct: 341 Q-DL---FIIDSTFGVLYL 355
Score = 69.3 bits (162), Expect = 8e-10
Identities = 47/139 (33%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Query: 1011 SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
++F L ISA + V VF++D ND+ PVF + Y V E Q + +V A
Sbjct: 1535 NKFNLIISA-ESSQYTTYCRVTVFIQDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAA 1593
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G N + Y I + + F + G+LS N LDRE + Y LTV A D G
Sbjct: 1594 DGDSGINGQIDYSIISGNENNAFVLDSRHGILSTNVILDREIKSSYRLTVQATDRG-SPS 1652
Query: 1131 XXXXXXXXXXXXDVNDNSP 1149
D+NDN+P
Sbjct: 1653 CSSTSVVTVLILDINDNAP 1671
Score = 67.3 bits (157), Expect = 3e-09
Identities = 55/170 (32%), Positives = 83/170 (48%), Gaps = 10/170 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D DLG+ T+ Y LI N F + G + L ++ L AE ++ VLQVQ
Sbjct: 1386 VHASDVDLGLNGTVVYNLIKSN--PFFYITQEKGEVKL--QMPLPAEF----SSTVLQVQ 1437
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT-DKDQG 336
AS L P T V I++ L+ + F +FY I+EN G V+ V A
Sbjct: 1438 ASDLGIPPNTVTGLVIIDIQGLDKEI-AFVHNFYEAIILENSEAGTLVVTVKALYHNPND 1496
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
E +T D KGAF+++P +G L V+ +LD E + + + A+ +
Sbjct: 1497 EIIHYTVFSGDKKGAFNLNPITGDLMVKEPRLLDFETVNKFNLIISAESS 1546
Score = 67.3 bits (157), Expect = 3e-09
Identities = 75/313 (23%), Positives = 135/313 (43%), Gaps = 29/313 (9%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI---- 121
D+ G +++ ++ + I D NDN P+F ++ YHV+V E P K+ I +I
Sbjct: 1965 DIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSVREHYPL--KSTIIIISATD 2022
Query: 122 APIGPSLTIPLTVPRG-----LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
+ G + I ++ G TI +P + YS+ DGH S
Sbjct: 2023 SDTGENADITYSIVSGNDENVFTIDAQNGTVTLVQPLDYEETMKYSLTLQARDGH---GS 2079
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEP---IHAIDQDLGVGATLRY 233
L + D D + + + I++ + F P ++AID D G L +
Sbjct: 2080 KRNVAFALLSITVLDENDFAPKFLFQSQSCNIYENVPFFSPVCSVNAIDLDSGQYGILSF 2139
Query: 234 ELISG--NDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+ S ND++ F +DS+ G ++ + +D + + + + V+QV+ + +A
Sbjct: 2140 SIQSSCFNDQQHPATFLIDSLTGDIYTKHRIDYEMQ---ERHCLVVQVK----DRSESSA 2192
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
V I++ ++ P F + Y + E G + +V A D D+G +G Y L+ P
Sbjct: 2193 CVLVYIDIEGEDEFQPVFYQNQYLFDLPEENIGGQEIGKVGALDNDEGLDGVVHYFLEKP 2252
Query: 349 KGAFSIDPRSGWL 361
FSI+ SG +
Sbjct: 2253 SQFFSINMTSGMI 2265
Score = 64.9 bits (151), Expect = 2e-08
Identities = 45/143 (31%), Positives = 72/143 (50%), Gaps = 8/143 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y +ISGN ++F++ + G + +KELD ++ VL VQ SQL + + +V
Sbjct: 230 YRIISGNVHQMFTIHTQFGIIRTQKELDFES-----LPLVVLTVQ-SQLGSSSVFSSTQV 283
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGA 351
+ + D NDN P F + IS+ +N G ++ ATD D G NG+ +Y + + +
Sbjct: 284 NVTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQDL 343
Query: 352 FSIDPRSGWLTVRNQTVLDREAH 374
F ID G L + N T+ H
Sbjct: 344 FIIDSTFGVLYL-NATLSSVREH 365
Score = 62.9 bits (146), Expect = 7e-08
Identities = 43/148 (29%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 218 IHAIDQDLGVGATLRYELISG----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D D G + Y + G + + F +D +G + + ++D ++ ++
Sbjct: 3 VKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESG----PTSYD 58
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V+A +AQA V +++ D+NDN P FE Y SI + G +L VMA D+
Sbjct: 59 LLVKAEDEGG--LSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDR 116
Query: 334 DQGENGEFTYQL--DDPKGAFSIDPRSG 359
D+G G+ TY+L + F+ID +G
Sbjct: 117 DEGLFGDVTYELLSGEHSSLFTIDSSTG 144
Score = 61.7 bits (143), Expect = 2e-07
Identities = 74/323 (22%), Positives = 127/323 (39%), Gaps = 27/323 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G + + + V V I D NDN P+F ++V + T G +I + +
Sbjct: 273 GSSSVFSSTQVNVTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQI 332
Query: 133 T---VPRGLTIFKDIRAFDRDKPNTPNSDV--HYSIVSGNDDGHFALESSHKPVLLLRKV 187
+ +F F N S V H ++ D GH + S +L L +
Sbjct: 333 SYSIASENQDLFIIDSTFGVLYLNATLSSVREHVLLILAEDYGHPVISS----LLTLTII 388
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAID----QDLGVGATLRYELISGNDRKL 243
++ + + I + + I + + + Y L D
Sbjct: 389 VEQNKQSNTLSFFNLVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAP 448
Query: 244 FSLDSVNGSLFLEKELDLDAE--HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F + G +FL + +D + HNL+ V S +TA A + +++LD ND
Sbjct: 449 FRIHQSTGWIFLRRSVDYEKSKTHNLKV------VATSGDREDQQTATASIIVKILDEND 502
Query: 302 NLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
N P F+ + ++ E+ +P+G + + A D+D G NG+ +Y L F I ++G
Sbjct: 503 NSPSFDHATHFFTVNESPVPHGV-IGSIQAFDRDSGNNGQLSYFLLSEGNNFLISSKTG- 560
Query: 361 LTVRNQTVLDRE--AHSSLRMKV 381
+ N LDRE AH L + V
Sbjct: 561 -EIINCASLDRERKAHHELNVLV 582
Score = 61.3 bits (142), Expect = 2e-07
Identities = 100/414 (24%), Positives = 167/414 (40%), Gaps = 52/414 (12%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+ E++ IG+ ++KL A D D GLN +I Y + + F +N
Sbjct: 1267 LVREDLKIGSAVLKLQASDADEGLNKEIMYSLID--------------DTQGAFTVNRTT 1312
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLND---NISVRVFVKDVNDHFPVFKKTWYNFN 1053
G+++ R+L E ++ + A D N + V V+++DVND+ PVF + +
Sbjct: 1313 GNIVTIRTLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTENPIHVL 1372
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ + + V A+D D G N + Y + S+ F I+ G + + L E
Sbjct: 1373 ISPKVLENKTIANVHASDVDLGLNGTVVYNLIKSNPF--FYITQEKGEVKLQMPLPAEFS 1430
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+L V A D G D+ D+ + + H + + N
Sbjct: 1431 ST-VLQVQASDLG----IPPNTVTGLVIIDIQ-------GLDKEIAFVHNFYEAIILENS 1478
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN---GLILYSLP-----QRKNQQ 1225
E+ ++ KA + N VF+ D N N G ++ P + N+
Sbjct: 1479 EAGTLVVTVKA-LYHNPNDEIIHYTVFSGDKKGAFNLNPITGDLMVKEPRLLDFETVNKF 1537
Query: 1226 NLGLPSLSS--TAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNL 1281
NL + + SS T VTV D + PVF Y + E N V V
Sbjct: 1538 NLIISAESSQYTTYCRVTVFIQDDN---DNAPVFDQLDYISFVSEGQPFNTFVIQVFAAD 1594
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N ++ Y I++ N+ + FV+D R+G L DRE+K +Y + V+A
Sbjct: 1595 GDSGINGQIDYSIISGNENN---AFVLDSRHGILSTNVILDREIKSSYRLTVQA 1645
Score = 60.5 bits (140), Expect = 3e-07
Identities = 71/310 (22%), Positives = 129/310 (41%), Gaps = 18/310 (5%)
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM-YDFEAVALQENANLSIVTNATVHV 666
YD H +E F ++ SG I V +D+ + + P YD V ++ LS V +
Sbjct: 21 YDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDL-LVKAEDEGGLSAQAFVRVDI 79
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQD 725
D+ND V + I G I + + ++G+ T L++ +
Sbjct: 80 EDINDNAPVFEPSTYVTSIS--SHTQPGTEILNVMAIDRDEGLFGDVTYE---LLSGEHS 134
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I + G I+ L + ++V A +KG ++ A VT+ I P
Sbjct: 135 SLFTID-SSTGIIYLISVLSHLEDSWVSLSVAAR-DKGGLTSAVNATVTMNILKTATAPA 192
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
+FE + Y I E+ G+ + +KA + + + G +MF + G+
Sbjct: 193 IFEKSRYTFVIAEDVPKGSAV---GTVKAREPLNSLEPVSYRIISGNVHQMFTIHTQFGI 249
Query: 846 VKFIGDSLDREKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
++ LD E + L++ ++ + + S ++ + I D NDN P F+ EN ++ +
Sbjct: 250 IR-TQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDNPPVFS--SENERISV 306
Query: 905 HRETKLNGTA 914
H+ T GTA
Sbjct: 307 HQNTS-PGTA 315
Score = 52.8 bits (121), Expect = 7e-05
Identities = 99/471 (21%), Positives = 187/471 (39%), Gaps = 41/471 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +LD NDN PVF N+Y+ ++ + T I V A D D G + Y + ++
Sbjct: 1761 IKVLDVNDNPPVFT-QNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKI-----IS 1814
Query: 507 ITSPFKINPNTGTVSVAESPILEGRH------ALFVEASDQPANPSERRYSLAVVTIEVT 560
F IN +G + + + G+ + + A D + P L+V ++V
Sbjct: 1815 PLKGFVINTTSGKLRSVYTDMPLGKENKSTEIQILIVAMDNGSPPLTSTAMLSVTILDVN 1874
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLHGYEEGVP 619
DI ++ + VG V T++ D +N + + ++ G +
Sbjct: 1875 NYAPTFSEDIY-YVNVSEDALVGDTVLTLTAMDL----DWSPKNALIDFSIIGGNAHNLF 1929
Query: 620 F--AVEERSGVITVVDDLSRYNRPMYDFEAVALQE------NANLSIVTNATVHVVDVND 671
+ + E S + +V N+P+ DFE + N + ++ ++++ D
Sbjct: 1930 YLESSEVLSHIPFIVTGKLIINQPL-DFEVASAHRLDIFVSNQGFPPLNSSATIIINILD 1988
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV-TDDI 730
++S V+E+ + I S N + N ++V T D
Sbjct: 1989 SNDNPPLFSNSEYHVSVREHYPLKSTIIIISATDSDTGENADITYSIVSGNDENVFTID- 2047
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
A++GT+ +PLD E+ Y +T+ A G ++I + DEND P F
Sbjct: 2048 --AQNGTVTLVQPLDYEETMKYSLTLQARDGHGSKRNVAFALLSITVLDENDFAPKFLFQ 2105
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKE--MFDVDENTG 844
+ I EN + + + A D D G + +++ F + + F +D TG
Sbjct: 2106 SQSCNIYENVPFFSPVCS---VNAIDLDSGQYGILSFSIQSSCFNDQQHPATFLIDSLTG 2162
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ + +D E + + L + +D S+ + I I E++ +P F Q
Sbjct: 2163 DI-YTKHRIDYEMQERHCLVVQVKDRSESSACVLVYIDIEGEDEFQPVFYQ 2212
Score = 50.0 bits (114), Expect = 5e-04
Identities = 46/184 (25%), Positives = 82/184 (44%), Gaps = 21/184 (11%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + P FL I EN+P + + +NA+DLDSG G + + S +
Sbjct: 2093 LDENDFAPKFLFQSQSCNIYENVPFFSPVCSVNAIDLDSGQYGILSFSIQSSCFNDQQHP 2152
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGNLNDNISVRVFVKDVN 1039
+ F+I+ G + + E + R L + D + + V + ++ +
Sbjct: 2153 AT--------FLIDSLTGDIYTKHRIDYEMQERHCLVVQVKDRSESSACVLVYIDIEGED 2204
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-PSDTDLPFEISPL 1098
+ PVF + Y F++ E + +GKV A D D G + + YF++ PS F I+
Sbjct: 2205 EFQPVFYQNQYLFDLPEENIGGQEIGKVGALDNDEGLDGVVHYFLEKPSQF---FSINMT 2261
Query: 1099 TGVL 1102
+G++
Sbjct: 2262 SGMI 2265
Score = 48.4 bits (110), Expect = 0.002
Identities = 78/361 (21%), Positives = 143/361 (39%), Gaps = 32/361 (8%)
Query: 988 VKRYFVINERHGHVIVARSLPPESEFRLNI---SALDGGNLNDNISVRVFVKDVNDHFPV 1044
V + F I+ + G + + L ES + + S L ++ + V V + D ND+ PV
Sbjct: 237 VHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDNPPV 296
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
F +V + + ATD D G N ++Y I + DL F I GVL +
Sbjct: 297 FSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQDL-FIIDSTFGVLYL 355
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
N L E ++L ++A D G + N+ F F+ + + E
Sbjct: 356 NATLSSVRE--HVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSF--FNLVHRTEISE 411
Query: 1165 ADELSNHNFESVMMIPVY-KATIEENAPIGTTVAKVFANDTDFIGNGNGLILY--SLPQR 1221
+++H ++ + Y + T ++ I +++ + I G I S+
Sbjct: 412 TLPINSH----ILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTGWIFLRRSVDYE 467
Query: 1222 KNQ-QNLGLPSLS--------STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
K++ NL + + S +TA ++V + D D D E + V
Sbjct: 468 KSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNESPVPHGVIG 527
Query: 1273 PVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
++ + N ++ Y++L+E + F+I + G + S DRE K +E+
Sbjct: 528 SIQAFD---RDSGNNGQLSYFLLSEGN-----NFLISSKTGEIINCASLDRERKAHHELN 579
Query: 1333 V 1333
V
Sbjct: 580 V 580
Score = 48.0 bits (109), Expect = 0.002
Identities = 58/244 (23%), Positives = 102/244 (41%), Gaps = 10/244 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID+D G+ + YEL+SG LF++DS G ++L L +L+ + L V
Sbjct: 111 VMAIDRDEGLFGDVTYELLSGEHSSLFTIDSSTGIIYLISVLS-----HLEDSWVSLSVA 165
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK-DQG 336
A A V + +L FE Y I E++P G +V V A + +
Sbjct: 166 ARDKGGLTSAVNATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREPLNSL 225
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
E + + F+I + G +R Q LD E+ + + V ++ + SV +
Sbjct: 226 EPVSYRIISGNVHQMFTIHTQFG--IIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQV 283
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+ I P ++ E+ + GT + D L S N +++ A++N
Sbjct: 284 NVTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATD--LDSGFNGQISYSIASENQ 341
Query: 457 PVFV 460
+F+
Sbjct: 342 DLFI 345
Score = 48.0 bits (109), Expect = 0.002
Identities = 46/154 (29%), Positives = 65/154 (42%), Gaps = 17/154 (11%)
Query: 218 IHAIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I A D+D G L Y L+S GN+ F + S G + LD + + + + N V
Sbjct: 529 IQAFDRDSGNNGQLSYFLLSEGNN---FLISSKTGEIINCASLDRERKAHHELNVLV--- 582
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEF----EVDFYNISIVENLPNGFSVLQVMATD 332
+ P + A V I + DLNDN P F ++ ++E V V A D
Sbjct: 583 --TDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVYAKD 640
Query: 333 KDQGENGEFTY--QLDDPKGAFSIDPRSG--WLT 362
D G NG Y D+ G F I+ +G W T
Sbjct: 641 PDAGNNGTVVYFFASDESFGQFVINASTGEIWTT 674
Score = 47.6 bits (108), Expect = 0.003
Identities = 103/439 (23%), Positives = 173/439 (39%), Gaps = 67/439 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE T I ++A D DS + G I Y+ I P K FVIN G
Sbjct: 1782 LPELTESNTFITTVSATDQDSEIYGPITYKI-----ISPLK----------GFVINTTSG 1826
Query: 1000 HV-IVARSLP-----PESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ V +P +E ++ I A+D G+ L + V + DVN++ P F + Y
Sbjct: 1827 KLRSVYTDMPLGKENKSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYY 1886
Query: 1052 FNVEEAQYTRRVLGKVDATDADF------------GQNANLTYFIQPSD--TDLPFEISP 1097
NV E + + A D D+ G NA+ ++++ S+ + +PF +
Sbjct: 1887 VNVSEDALVGDTVLTLTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIV-- 1944
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
TG L +N LD E + L + + G D NDN P F +
Sbjct: 1945 -TGKLIINQPLDFEVASAHRLDIFVSNQG-FPPLNSSATIIINILDSNDNPPLFSNSEYH 2002
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI----GNGNGL 1213
+ + E L + ++++I + ENA I T + V ND + NG
Sbjct: 2003 VSVR--EHYPLKS----TIIIISATDSDTGENADI--TYSIVSGNDENVFTIDAQNGTVT 2054
Query: 1214 ILYSLPQRKN-------QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEI 1266
++ L + Q G S + A ++++ V DE + + P F+ + I
Sbjct: 2055 LVQPLDYEETMKYSLTLQARDGHGSKRNVAFALLSIT-VLDENDFA--PKFLFQSQSCNI 2111
Query: 1267 EENVNAPVELVSLNLTE----HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
ENV + S+N + Y ND TF+ID G +Y D
Sbjct: 2112 YENVPFFSPVCSVNAIDLDSGQYGILSFSIQSSCFNDQQHPATFLIDSLTGDIYTKHRID 2171
Query: 1323 REVKDTYEVIVRAERQKYS 1341
E+++ + ++V+ + + S
Sbjct: 2172 YEMQERHCLVVQVKDRSES 2190
Score = 47.2 bits (107), Expect = 0.003
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 7/102 (6%)
Query: 812 IKATDADEGTNALFMYTLFG-----EGKEMFDVDENTGVVKFIGDSLDREK-KIMYKLSL 865
+KATDAD G Y+++ + + F +D ++G + + + +D+E Y L +
Sbjct: 3 VKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRI-CVSNDIDKESGPTSYDLLV 61
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
A D GGLS++A + + I D NDN P F + + H +
Sbjct: 62 KAEDEGGLSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQ 103
Score = 47.2 bits (107), Expect = 0.003
Identities = 108/520 (20%), Positives = 194/520 (37%), Gaps = 49/520 (9%)
Query: 887 NDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI 946
ND E + V+ E L+ A F ++++ N A + + I +
Sbjct: 46 NDIDKESGPTSYDLLVKAEDEGGLSAQA-FVRVDIEDINDNAPVFEPSTYVTSISSHTQP 104
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG--HVIVA 1004
GT I+ + A+D D GL G + YE S E F I+ G ++I
Sbjct: 105 GTEILNVMAIDRDEGLFGDVTYELLSG-------------EHSSLFTIDSSTGIIYLISV 151
Query: 1005 RSLPPESEFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
S +S L+++A D G L N +V + + +F+K+ Y F + E
Sbjct: 152 LSHLEDSWVSLSVAARDKGGLTSAVNATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGS 211
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+G V A + ++Y I + F I G++ ELD E+ +LTV
Sbjct: 212 AVGTVKARE-PLNSLEPVSYRIISGNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTV-- 268
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
+ D NDN P F + +E + + + + ++ + +
Sbjct: 269 QSQLGSSSVFSSTQVNVTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGF 328
Query: 1183 KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK---NQQNLGLPSLSSTAILM 1239
I + I + +F D+ F L S+ + ++ G P +SS +
Sbjct: 329 NGQISYS--IASENQDLFIIDSTFGVLYLNATLSSVREHVLLILAEDYGHPVISS----L 382
Query: 1240 VTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEND 1299
+T+ + ++ + S+ F + + EI E +L + H +++ Y N
Sbjct: 383 LTLTIIVEQNKQSNTLSFFNLVHRTEISE---------TLPINSHI--LQVKAYTRNTQS 431
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA-EDVLEG 1358
T + + P + +P R + T + +R Y + H + VA E
Sbjct: 432 TSSEIMYSLSPT-----IDSAPFRIHQSTGWIFLR-RSVDYEKSKTHNLKVVATSGDRED 485
Query: 1359 MTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
++V+I D NDNSP F + T + P G
Sbjct: 486 QQTATASIIVKILDENDNSPSFDHATH-FFTVNESPVPHG 524
Score = 46.4 bits (105), Expect = 0.006
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Query: 227 VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
+ + + Y L + ++ F +DS+ G +++ + LD + + + ++ +++ P
Sbjct: 761 LSSKMHYRLANEENKGHFVVDSLTGDVYVSRHLDFETISYYGLSIDIQEI--DKISPPNL 818
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG-ENGEFTYQL 345
+ + IE D ND+ P F + + E++P G + A DKD EN + Y L
Sbjct: 819 SVFLTIYIE--DTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLENSKIRYSL 876
Query: 346 D---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ + F I G LT N+ LDRE S + V A +
Sbjct: 877 NTHGTGENPFFIHEWEGALTTANE--LDREMAESFVLTVTATD 917
Score = 45.6 bits (103), Expect = 0.011
Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 16/169 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + Y + S N + LF +DS G L+L L EH VL + A
Sbjct: 321 ATDLDSGFNGQISYSIASEN-QDLFIIDSTFGVLYLNATLSSVREH-------VLLILAE 372
Query: 280 QLNNPLKTAQARVEIELLDLN--DNLPEFEVDFYNISIVENLPNGFSVLQVMA-TDKDQG 336
+P+ ++ + I +++ N N F + I E LP +LQV A T Q
Sbjct: 373 DYGHPVISSLLTLTI-IVEQNKQSNTLSFFNLVHRTEISETLPINSHILQVKAYTRNTQS 431
Query: 337 ENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ E Y L F I +GW+ +R +D E + +KV A
Sbjct: 432 TSSEIMYSLSPTIDSAPFRIHQSTGWIFLRRS--VDYEKSKTHNLKVVA 478
Score = 35.9 bits (79), Expect = 8.6
Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 1429 ERLSLNGLTSP-------QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALA 1480
ER+S++ TSP QATD D G N I Y I +E F ID G + + A L+
Sbjct: 302 ERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQDLFIIDSTFGVLYLNATLS 360
>UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous-2 -
Homo sapiens (Human)
Length = 2916
Score = 122 bits (293), Expect = 1e-25
Identities = 129/476 (27%), Positives = 214/476 (44%), Gaps = 33/476 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVLY 497
L S V + + + D ND++P F L S++ N +GT++ A D D N + Y
Sbjct: 1035 LSSTVFLSIDVEDQNDHSPSF-QDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQY 1093
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVV 555
++ S+ T+PF I+P+ GT+ E L V ASDQ N ++RR
Sbjct: 1094 YIE--SHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTA 1151
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG 613
I + N P F+ P V +V +G+ V I +D E + V+Y +L G
Sbjct: 1152 QIVILDVNDHN----PTFISFPNAH-VKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSG 1206
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
E + F ++E SG++T L + + +AL + LS TV V+DVNDE
Sbjct: 1207 -NENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDE 1265
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-- 730
V + + VKEN F T + ++ + N + + ++
Sbjct: 1266 APVFKQHLYEA---SVKENQNPGE----FVTRVEALDRDSGVNSKLQFEIMPGASFELFE 1318
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
++ G + T LDRE ++V+ + V+ + G S + + +EDEND+ P F +
Sbjct: 1319 INSDTGEVVTTTILDREIQEVFTLRVLVR-DGGFPSLSSTTTILCTVEDENDHAPEFIVS 1377
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
+Y+ ++EN E ++ + A+D D G N Y + G E F ++E +G +
Sbjct: 1378 SYDIEVLENQ----EPEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSGELSTT 1433
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+LDRE+ + L ++ D G SS L + + D ND+ P F + S VR
Sbjct: 1434 R-ALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVR 1488
Score = 119 bits (287), Expect = 5e-25
Identities = 168/687 (24%), Positives = 285/687 (41%), Gaps = 58/687 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
LRY L D +F + G ++L ++ D ++ F + L N T
Sbjct: 621 LRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVIV 680
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
RV D NDN P F D + + E+ +P G + ++ A D D G+NG+ Y L
Sbjct: 681 RV----WDENDNSPTFLHDVLFLKVEESPVPQGV-IGKITAIDMDSGKNGQLLYFLLSDG 735
Query: 350 GAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKETNPSVV--GTFAD--SQRIAKWR 404
F ++P +G T+ T D A S ++ + + V F + + W
Sbjct: 736 KFFKMNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWV 795
Query: 405 RQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF---VP 461
E E T V D+ G+ N + + V V++ D NDN P F +P
Sbjct: 796 ALDREHRGHHEMTVLV-TDR-GSPPRN---------ATMAVYVSVTDINDNRPFFPQCLP 844
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS 521
+ V ++ V A DPD G N V Y + S+ + FKI+ N G +
Sbjct: 845 GKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSV---SSEDSSDHFKIDANNGEIR 901
Query: 522 VAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE 579
+ R + + V A+DQ P + + AVV I+V +KG +
Sbjct: 902 TTTILSYDYRPSYRMSVIATDQGVPPLQGQ---AVVNIQVIPLSKGRAIMSQNIR----H 954
Query: 580 FWVGSNVGIGTSVGQIRVNDAFEQN---DVSYDLLHGYEEGVPFAVEERSGVITVVDDLS 636
+ N+ + I+ +D +Q+ + + ++ ++G F ++ +G + + +L
Sbjct: 955 LIIPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDG-HFEIDSSTGDLFLSKELD 1013
Query: 637 RYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGAHSPIIFHVKENSAGA 695
Y F + + NLS+ ++TV + +DV D+ I+ V+EN
Sbjct: 1014 YETTSHYLFRVITTDHSKNLSL--SSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIG 1071
Query: 696 AIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYR 753
+ +F N G+ +++ I + T+ I GT+ T LDRE
Sbjct: 1072 TLVYVF--NAKDDDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVI 1129
Query: 754 MTVIAEFNKGVISGAGIYQVT--IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
+TV A ++ + +T I I D ND+ P F + + E+ +G+ + +
Sbjct: 1130 LTVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTF-ISFPNAHVKEDVTVGSLV---HH 1185
Query: 812 IKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
I A D DEG N Y++ + M F +DE++G++ LD E K + L+++A D
Sbjct: 1186 ITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLT-TTCPLDYEMKTQHILTVLALDD 1244
Query: 871 G--GLSSEAELIIMIGDENDNKPEFNQ 895
G LSS L + + D ND P F Q
Sbjct: 1245 GTPALSSSQTLTVTVLDVNDEAPVFKQ 1271
Score = 118 bits (284), Expect = 1e-24
Identities = 114/482 (23%), Positives = 208/482 (43%), Gaps = 39/482 (8%)
Query: 425 VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKA 484
V + + D +L S + ++ +LD ND+NP F+ + +K + VG+++ + A
Sbjct: 1132 VTASDQAVNVTDRRLRS-LTAQIVILDVNDHNPTFI--SFPNAHVKEDVTVGSLVHHITA 1188
Query: 485 VDPDLGQNGMVLYD-LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASD 540
DPD G+NG V Y L N+T F ++ ++G ++ P+ ++ +H L V A D
Sbjct: 1189 HDPDEGRNGKVTYSILSGNENMT----FMLDESSGLLTTT-CPLDYEMKTQHILTVLALD 1243
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--N 598
+L V ++V + P F YE V N G V ++
Sbjct: 1244 DGTPALSSSQTLTVTVLDV-------NDEAPVFKQHLYEASVKENQNPGEFVTRVEALDR 1296
Query: 599 DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLS 657
D+ + + ++++ G + F + +G + L R + ++ + +LS
Sbjct: 1297 DSGVNSKLQFEIMPGASFEL-FEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLS 1355
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
T V D ND + ++ V EN + + ++M + GN
Sbjct: 1356 STTTILCTVEDENDHAPEFIVSSYD---IEVLENQEPEVVYTVLASDMDA--GNNRAVEY 1410
Query: 718 FLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+I D + I E G + T + LDRE+ + + ++ + G + + + +
Sbjct: 1411 HIIDGNTD--ECFTINEMSGELSTTRALDREQISNFTLVILCS-DLGDPPRSSVIHLQVR 1467
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D ND+ P F Y+ + E++++GT + ++ A D DEG N Y L E
Sbjct: 1468 VLDANDHSPSFPTLYYQSSVREDAEVGTVVL---VLSAVDKDEGLNGQTEYFLTDEASGA 1524
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDNKPEF 893
F +D +G +K ++LDRE + + S VARD G S+ + + + D NDN P
Sbjct: 1525 FTIDPMSGTLK-TSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVL 1583
Query: 894 NQ 895
Q
Sbjct: 1584 EQ 1585
Score = 113 bits (273), Expect = 3e-23
Identities = 153/609 (25%), Positives = 260/609 (42%), Gaps = 45/609 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D S ++++V +LDAND++P F P+ Y+ S++ +A+VGTV+ + AVD D G NG
Sbjct: 1455 DPPRSSVIHLQVRVLDANDHSPSF-PTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQT 1513
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y L ++ F I+P +GT+ + + E R A + + R + ++
Sbjct: 1514 EYFLTDEAS----GAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVII 1569
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+ VT N P + P++ ++ + +R +D + + E
Sbjct: 1570 KVYVT-DVNDNDPVLEQ---NPFDVFLSPESPTNQTTVIVRADD-LDLGPNGTVVFSFAE 1624
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
F++++ +G I + S P++ V Q + T + V+ + E V
Sbjct: 1625 TQSMFSIDKYTGEIQFQQNPSSEYFPIWLQLKVTDQ---GIPARTTTGLLVIHMEGE-DV 1680
Query: 676 LLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
+ +H V EN AG +I + SI + ++ N+ V + +
Sbjct: 1681 KISFSHHLYKGLVTENCEAGTSIVTVKAFAPDSIQDSMKYSI--FSGNEDGVLSLCSKSG 1738
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY-QVTIYIEDENDNPPVFEHATYE 793
T+ K LD E R+ ++ V+AE SG Y +V + I+DENDN P FE + Y+
Sbjct: 1739 QLTVKEPKFLDFEVRNEVQLIVLAES-----SGHRAYCKVAVLIQDENDNSPCFEQSIYQ 1793
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKFIGDS 852
+ E+ + + ATD D G N L Y+ L G +E F +D +GV+
Sbjct: 1794 ASVSESQLYNAHVIQ---VFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVIT-TKAI 1849
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LD E Y L + A D G LS+ + + + D NDN P F E V I E L
Sbjct: 1850 LDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAFLPSE---AVEI-TEDSL 1905
Query: 911 NG--TAGFTIIEVKPKNKFALDV---DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
G ++ +V + F G F I +N + ++ + LD + +
Sbjct: 1906 PGVIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQNTGV---VVLVKTLDFEEMTEYE 1962
Query: 966 IRYEFNSEVYIPPSKLSADALEVK-RYFVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
+ + + V+ L L+V V ++ V V S+P L +SA D +
Sbjct: 1963 LLIQISDSVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSV-LTLSATDLES 2021
Query: 1025 LNDNISVRV 1033
N+NIS R+
Sbjct: 2022 -NENISYRI 2029
Score = 104 bits (249), Expect = 2e-20
Identities = 88/326 (26%), Positives = 151/326 (46%), Gaps = 27/326 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI----GPSL 128
G +S+ ++TV + DVND P+F Y +V E GE F+ + + G +
Sbjct: 1245 GTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGE--FVTRVEALDRDSGVNS 1302
Query: 129 TIPLTVPRGLTI-FKDIRAFDRDKPNTPNSDVH----YSIVSGNDDGHFALESSHKPVLL 183
+ + G + +I + + T D +++ DG F SS +L
Sbjct: 1303 KLQFEIMPGASFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILC 1362
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGND 240
+ D D + ++ + + E PE ++ + D D G + Y +I GN
Sbjct: 1363 TVE----DENDHAPEFIVSSYDIEV-LENQEPEVVYTVLASDMDAGNNRAVEYHIIDGNT 1417
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
+ F+++ ++G L + LD + Q + F L + S L +P +++ +++ +LD N
Sbjct: 1418 DECFTINEMSGELSTTRALDRE-----QISNFTLVILCSDLGDPPRSSVIHLQVRVLDAN 1472
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSG 359
D+ P F +Y S+ E+ G VL + A DKD+G NG+ Y L D+ GAF+IDP SG
Sbjct: 1473 DHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSG 1532
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE 385
T++ LDREA S A++
Sbjct: 1533 --TLKTSNTLDREARSQHTFSAVARD 1556
Score = 100 bits (239), Expect = 4e-19
Identities = 111/465 (23%), Positives = 199/465 (42%), Gaps = 44/465 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V + D NDN P F+PS E + ++ G ++ V D DL N ++ + SN
Sbjct: 1878 IKVQVTDINDNAPAFLPSEAVEIT--EDSLPGVIVTHVSVHDVDL--NSAFIFSFAKESN 1933
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I+ NTG V + ++ E + L ++ SD Y+ + + V
Sbjct: 1934 PG--TKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSV------HYTEGALVVRVL-- 1983
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P F Y+ V ++ +G SV + D ++SY +L +E F++
Sbjct: 1984 DVNDNP--PVFSQDFYQVTVPESIPVGYSVLTLSATDLESNENISYRILSSSKE---FSI 2038
Query: 623 EERSGVITVVDD---LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL-LK 678
+ ++G I + L + + EA + N +L +T + + D+N+ +K
Sbjct: 2039 DPKNGTIFTISPVLLLDTISTTQFLVEA-SDGGNPDLRALTLVEIGIEDMNNYAPEFTVK 2097
Query: 679 GAHSPIIFHVKENSAGAAIGQIFH--------TNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ + S I H S I GN N + +
Sbjct: 2098 SYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFH---VETKFFHSEY 2154
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G + LDRE + + ++A + G + ++I + D NDNPP F
Sbjct: 2155 PYKQVGYLVLLHSLDREASASHELVILAS-DSGCPPLSSTAVISIQVLDVNDNPPNFSSL 2213
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
+Y + E++ +G+ I ++ A D D G++A +Y + G K F ++ENTGV+ I
Sbjct: 2214 SYHTHVKESTPLGSHI---TVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLI 2270
Query: 850 GDSLDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEF 893
LD EK + L++ A D S A + + + D+ND+ P+F
Sbjct: 2271 -KPLDYEKMTKFTLTVQASDAEKKHFSFAVVFVSVLDDNDHAPQF 2314
Score = 97.5 bits (232), Expect = 2e-18
Identities = 115/438 (26%), Positives = 194/438 (44%), Gaps = 49/438 (11%)
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEV 974
F I+V+ +N + + + EN+PIGT + NA D D S LN +I+Y
Sbjct: 1040 FLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQY------ 1093
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG-NLND---- 1027
YI + F+I+ G ++ L ES L ++A D N+ D
Sbjct: 1094 YIESHNPGTNP------FLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLR 1147
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+++ ++ + DVNDH P F ++ N +V+E ++ + A D D G+N +TY I
Sbjct: 1148 SLTAQIVILDVNDHNPTFI-SFPNAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSG 1206
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
+ ++ F + +G+L+ LD E + ++ILTV+A D+G DVND
Sbjct: 1207 NENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDG-TPALSSSQTLTVTVLDVNDE 1265
Query: 1148 SPKFYAFDELLEWKHPEADELSNHN-FESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
+P F + L EA N N E V + N+ + + + +
Sbjct: 1266 AP---VFKQHLY----EASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFE 1318
Query: 1207 IGNGNG-LILYSLPQRKNQQ---------NLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
I + G ++ ++ R+ Q+ + G PSLSST ++ TV D D P
Sbjct: 1319 INSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHA-----PE 1373
Query: 1257 FISRYYELEIEENVNAPVELVSL-NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
FI Y++E+ EN V L + + N + Y+I++ N TD F I+ +G L
Sbjct: 1374 FIVSSYDIEVLENQEPEVVYTVLASDMDAGNNRAVEYHIIDGN-TD--ECFTINEMSGEL 1430
Query: 1316 YLVRSPDREVKDTYEVIV 1333
R+ DRE + +++
Sbjct: 1431 STTRALDREQISNFTLVI 1448
Score = 97.5 bits (232), Expect = 2e-18
Identities = 105/418 (25%), Positives = 177/418 (42%), Gaps = 34/418 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + VT+LD ND PVF +LYE S+K N G + +V+A+D D G N + ++
Sbjct: 1249 LSSSQTLTVTVLDVNDEAPVF-KQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFE 1307
Query: 499 LQRTSNLTITSPFKINPNTG---TVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ ++ + F+IN +TG T ++ + I E L V D PS + +
Sbjct: 1308 IMPGASFEL---FEINSDTGEVVTTTILDREIQE-VFTLRVLVRD-GGFPSLSSTTTILC 1362
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN-DAFEQNDVSYDLLHGY 614
T+E P+F+ + Y+ V N + + DA V Y ++ G
Sbjct: 1363 TVE------DENDHAPEFIVSSYDIEVLENQEPEVVYTVLASDMDAGNNRAVEYHIIDGN 1416
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDVND 671
+ F + E SG ++ L R + +F V L + S V + V V+D ND
Sbjct: 1417 TDEC-FTINEMSGELSTTRALDR--EQISNFTLVILCSDLGDPPRSSVIHLQVRVLDAND 1473
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDI 730
P +++ A +G + + G G + + ++ I
Sbjct: 1474 H------SPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTI 1527
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
GT+ T LDRE R + + +A S + + +Y+ D NDN PV E
Sbjct: 1528 D-PMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQN 1586
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
++ F+ S + I++A D D G N +++ F E + MF +D+ TG ++F
Sbjct: 1587 PFDVFLSPESPTN---QTTVIVRADDLDLGPNGTVVFS-FAETQSMFSIDKYTGEIQF 1640
Score = 94.3 bits (224), Expect = 2e-17
Identities = 164/701 (23%), Positives = 286/701 (40%), Gaps = 81/701 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ V V + D NDN+P F S +Y+ S+ + + +V A D D G NG++ Y +
Sbjct: 1769 AYCKVAVLIQDENDNSPCFEQS-IYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSIL 1827
Query: 501 RTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ F+I+ +G ++ L ++L V+A+D+ R + V+ ++
Sbjct: 1828 SGNQ---EEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGM---PRLSNTTVIKVQ 1881
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
VT +P E + + SV + +N AF + G
Sbjct: 1882 VTDINDNAPAFLPSEAVEITEDSLPGVIVTHVSVHDVDLNSAF-----IFSFAKESNPGT 1936
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVDVNDERGVLL 677
FA+++ +GV+ +V L Y+ + +Q + ++ A V V+DVND V
Sbjct: 1937 KFAIDQNTGVVVLVKTLDFEEMTEYE---LLIQISDSVHYTEGALVVRVLDVNDNPPVFS 1993
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ + + + G ++ + T++ S N + R L ++++ D ++GT
Sbjct: 1994 QDFYQVTV--PESIPVGYSVLTLSATDLES---NENISYRILSSSKEFSIDP----KNGT 2044
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
IFT P+ ++ + G + V I IED N+ P F +Y +
Sbjct: 2045 IFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLS 2104
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
E++ +G+ + + I E T + + G + F V+ KF K
Sbjct: 2105 EDALVGSTLVTFSNIDHDWTRENTYVEYSI-ISGNSQNNFHVE-----TKFFHSEYPY-K 2157
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
++ Y + L + D +S EL+I+ D L+ TA +
Sbjct: 2158 QVGYLVLLHSLDREASASH-ELVILASDSGC-------------------PPLSSTAVIS 2197
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I +V N + L + E+ P+G+ I ++A D D+G + +I Y S
Sbjct: 2198 I-QVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEIIYNIISG---- 2252
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVR-VF 1034
K +F + E G + + + L E ++F L + A D + + +V V
Sbjct: 2253 ---------NEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEKKHFSFAVVFVS 2303
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPS------ 1087
V D NDH P F + ++ V E + ++A D D G LTY + P
Sbjct: 2304 VLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVSPCFLTHGM 2363
Query: 1088 --DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D DL F I PLTG + LD E +KY LTV A+D G
Sbjct: 2364 SYDHDL-FLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKG 2403
Score = 91.9 bits (218), Expect = 1e-16
Identities = 76/291 (26%), Positives = 132/291 (45%), Gaps = 18/291 (6%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V ++D ND+ P F+++ Y +V E+Q + +V ATD D G N + Y I + +
Sbjct: 1773 VAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQE 1832
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F+I L+GV++ LD E Y L V A D G D+NDN+P
Sbjct: 1833 EAFQIDALSGVITTKAILDYELTSSYSLIVQATDKG-MPRLSNTTVIKVQVTDINDNAPA 1891
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGN 1209
F EA E++ + V++ V ++ N+ + AK T F I
Sbjct: 1892 FLP---------SEAVEITEDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQ 1942
Query: 1210 GNG-LILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELEIE 1267
G ++L + L S ++ A V ++++D PVF +Y++ +
Sbjct: 1943 NTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVP 2002
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
E++ +++L+ T+ N + Y IL+ + + F IDP+NGT++ +
Sbjct: 2003 ESIPVGYSVLTLSATDLESNENISYRILSSS-----KEFSIDPKNGTIFTI 2048
Score = 90.2 bits (214), Expect = 4e-16
Identities = 182/835 (21%), Positives = 313/835 (37%), Gaps = 71/835 (8%)
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
+F Y F V +V + +G ++ + ++ + + + G F++ R G I
Sbjct: 376 EFERPKYTFLVYEDVPEDSPIGTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRT 435
Query: 632 VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN 691
L +P+ A +A T + V+DVND L+ S I +
Sbjct: 436 RKPLDHETQPVVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAFLR--TSDEIRISQTT 493
Query: 692 SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDV 751
G A ++ G +R+ IA+ Q I A G +F L ++
Sbjct: 494 PPGTA---LYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRAL-GVLFLNGSLGAGEQRE 549
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP-VFEHATYEGFIMENSKIGTEIKMDN 810
+T+ AE ++GV A + +T+ IE +P FEH Y+ + E+ T++ +
Sbjct: 550 LTLTLRAE-DQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQM-LQT 607
Query: 811 IIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA--R 868
+ L MF + TG + ++ D E Y + A
Sbjct: 608 QAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWI-YLRRQFDYESTQTYNFRVFAWIP 666
Query: 869 DTGGLSS-EAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG-FTIIEVKPKNK 926
+ G L + +I+ + DENDN P F + + +++ G G T I++
Sbjct: 667 EDGFLQNVSTTVIVRVWDENDNSPTF--LHDVLFLKVEESPVPQGVIGKITAIDMDSGKN 724
Query: 927 FALDVDQL--GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
L L G F + N TI + D + +G + F+S+ +L A
Sbjct: 725 GQLLYFLLSDGKFFKMNPNTGPAGTIYVITWADGAAAFSG-TDFAFSSD------ELQAF 777
Query: 985 ALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHF 1042
L+ + + E VA + + D G+ N ++V V V D+ND+
Sbjct: 778 VLK-SLFCELGEGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNR 836
Query: 1043 PVFKKTW----YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL 1098
P F + + V E Q ++ V A D D G NA +TY + D+ F+I
Sbjct: 837 PFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDAN 896
Query: 1099 TGVLSVNGELDRETEDKYILTVVARD------NGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
G + L + Y ++V+A D G ++ N
Sbjct: 897 NGEIRTTTILSYDYRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLI 956
Query: 1153 AFDELLEWKHPEADELSNH---NFESVMMIPVYKATIEENAPIGTTVAKVF-ANDTDFIG 1208
+ L K + S+H ++ + + + + I ++ +F + + D+
Sbjct: 957 IPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYET 1016
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
+ L+ + + +NL SLSST L + V D D P F + +EE
Sbjct: 1017 TSH--YLFRVITTDHSKNL---SLSSTVFLSIDVEDQNDH-----SPSFQDELIVISVEE 1066
Query: 1269 NVNAPVELVSLNLTE---HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
NV + N + + N +++YYI + N F+I P GTL V DRE
Sbjct: 1067 NVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPG--TNPFLIHPSFGTLVTVSRLDRES 1124
Query: 1326 KDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
T + V A Q + V + L +T V I DVND++P F
Sbjct: 1125 IPTVILTVTASDQAVN---------VTDRRLRSLTAQIV-----ILDVNDHNPTF 1165
Score = 81.0 bits (191), Expect = 2e-13
Identities = 102/399 (25%), Positives = 159/399 (39%), Gaps = 42/399 (10%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F INE G + R+L E S F L I D G+ + I ++V V D NDH P F
Sbjct: 1421 FTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPT 1480
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
+Y +V E V+ + A D D G N YF+ + F I P++G L +
Sbjct: 1481 LYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLT-DEASGAFTIDPMSGTLKTSNT 1539
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP--KFYAFDELLEWKHPEA 1165
LDRE ++ + VARD DVNDN P + FD L + P
Sbjct: 1540 LDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTN 1599
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
+ + + P + + F N + Q K
Sbjct: 1600 QTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDKYTGEIQFQQNPSSEYFPIWLQLK-VT 1658
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN-LTEH 1284
+ G+P+ ++T +L++ + ++V++S F Y+ + EN A +V++
Sbjct: 1659 DQGIPARTTTGLLVIHMEG--EDVKIS----FSHHLYKGLVTENCEAGTSIVTVKAFAPD 1712
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP---DREVKDTYEVIVRAERQKYS 1341
M+Y I + N+ + + ++G L V+ P D EV++ ++IV AE
Sbjct: 1713 SIQDSMKYSIFSGNEDGV---LSLCSKSGQL-TVKEPKFLDFEVRNEVQLIVLAESS--- 1765
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
H Y KV V I+D NDNSP F
Sbjct: 1766 ---GHRAY--------------CKVAVLIQDENDNSPCF 1787
Score = 79.8 bits (188), Expect = 5e-13
Identities = 70/234 (29%), Positives = 104/234 (44%), Gaps = 26/234 (11%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F + EN G + ++ ALD DSG+N ++++E +P +
Sbjct: 1260 LDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEI-----MPGASF 1314
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKD 1037
F IN G V+ L E + F L + DGG +L+ ++ V+D
Sbjct: 1315 --------ELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVED 1366
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
NDH P F + Y+ V E Q V+ V A+D D G N + Y I +TD F I+
Sbjct: 1367 ENDHAPEFIVSSYDIEVLENQ-EPEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTINE 1425
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++G LS LDRE + L ++ D G D ND+SP F
Sbjct: 1426 MSGELSTTRALDREQISNFTLVILCSDLG-DPPRSSVIHLQVRVLDANDHSPSF 1478
Score = 79.4 bits (187), Expect = 7e-13
Identities = 93/367 (25%), Positives = 151/367 (41%), Gaps = 38/367 (10%)
Query: 991 YFVINERHGHVIVARSLPPE--SEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVF 1045
+F I+ G + +++ L E S + + D +L+ + + + V+D NDH P F
Sbjct: 996 HFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLSIDVEDQNDHSPSF 1055
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDTDL-PFEISPLTGVLS 1103
+ +VEE ++ +A D D N+ + Y+I+ + PF I P G L
Sbjct: 1056 QDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLV 1115
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX--DVNDNSPKFYAFDELLEWK 1161
LDRE+ ILTV A D DVND++P F +F +
Sbjct: 1116 TVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFPNAHVKE 1175
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-- 1219
L +H I + N + ++ N T + +GL+ + P
Sbjct: 1176 DVTVGSLVHH-------ITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLD 1228
Query: 1220 -QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
+ K Q L G P+LSS+ L VTV DV DE PVF YE ++EN N
Sbjct: 1229 YEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDEA-----PVFKQHLYEASVKENQN 1283
Query: 1272 APVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD-- 1327
+ + + N K+++ I+ ++ F I+ G + DRE+++
Sbjct: 1284 PGEFVTRVEALDRDSGVNSKLQFEIMPGASFEL---FEINSDTGEVVTTTILDREIQEVF 1340
Query: 1328 TYEVIVR 1334
T V+VR
Sbjct: 1341 TLRVLVR 1347
Score = 76.2 bits (179), Expect = 7e-12
Identities = 79/315 (25%), Positives = 134/315 (42%), Gaps = 19/315 (6%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVP 135
S + + VY+ DVNDN P+ P+ V + +PT + I +GP+ T+ +
Sbjct: 1564 STTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFA 1623
Query: 136 RGLTIFK-DIRAFDRDKPNTPNSDVH--YSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
++F D + P+S+ + + D G A ++ V+ + +
Sbjct: 1624 ETQSMFSIDKYTGEIQFQQNPSSEYFPIWLQLKVTDQGIPARTTTGLLVIHMEGEDVKIS 1683
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGS 252
++ I+ + A D + +++Y + SGN+ + SL S +G
Sbjct: 1684 FSHHLYKGLVTENCEAGTSIV---TVKAFAPD-SIQDSMKYSIFSGNEDGVLSLCSKSGQ 1739
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L +++ LD E + VL + A +V + + D NDN P FE Y
Sbjct: 1740 LTVKEPKFLDFEVRNEVQLIVLAESSGH------RAYCKVAVLIQDENDNSPCFEQSIYQ 1793
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLD 370
S+ E+ V+QV ATD D G NG Y + + + AF ID SG +T + +LD
Sbjct: 1794 ASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTK--AILD 1851
Query: 371 REAHSSLRMKVYAKE 385
E SS + V A +
Sbjct: 1852 YELTSSYSLIVQATD 1866
Score = 74.5 bits (175), Expect = 2e-11
Identities = 44/151 (29%), Positives = 83/151 (54%), Gaps = 7/151 (4%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++PEN+PI +TI +NALD D+G G++ Y S ++ +S D F+I+
Sbjct: 2322 IVPENLPISSTICSINALDFDAGPYGELTYSIVSPCFLTHG-MSYD----HDLFLIDPLT 2376
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + + L E+ ++ L + A D G+ ++ V V ++ +++ P+F + Y F + E
Sbjct: 2377 GDIHAKQILDYENGNKYCLTVQAKDKGDATASLVVWVDIEGIDEFEPIFTQDQYFFTLPE 2436
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
R+++G+V+A+DAD G + + Y + S
Sbjct: 2437 KNKDRQLIGRVEASDADAGIDGVILYSLGTS 2467
Score = 74.1 bits (174), Expect = 3e-11
Identities = 56/178 (31%), Positives = 85/178 (47%), Gaps = 18/178 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G A + Y +ISGN++ F L+ G L+L K LD + + F L VQ
Sbjct: 2232 VSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYE-----KMTKFTLTVQ 2286
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS + A V + +LD ND+ P+F ++ + ENLP ++ + A D D G
Sbjct: 2287 ASDAEKK-HFSFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGP 2345
Query: 338 NGEFTYQLDDP----------KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
GE TY + P F IDP +G + + +LD E + + V AK+
Sbjct: 2346 YGELTYSIVSPCFLTHGMSYDHDLFLIDPLTG--DIHAKQILDYENGNKYCLTVQAKD 2401
Score = 71.7 bits (168), Expect = 1e-10
Identities = 67/229 (29%), Positives = 102/229 (44%), Gaps = 14/229 (6%)
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPI 218
H V DDG AL SS L VLD + F Q + AS K F +
Sbjct: 1235 HILTVLALDDGTPALSSSQT---LTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRV 1291
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A+D+D GV + L++E++ G +LF ++S G + LD + + F L+V
Sbjct: 1292 EALDRDSGVNSKLQFEIMPGASFELFEINSDTGEVVTTTILDREIQ-----EVFTLRVLV 1346
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P ++ + + D ND+ PEF V Y+I ++EN V V+A+D D G N
Sbjct: 1347 RDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLEN-QEPEVVYTVLASDMDAGNN 1405
Query: 339 GEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y + D F+I+ SG L+ LDRE S+ + + +
Sbjct: 1406 RAVEYHIIDGNTDECFTINEMSGELSTTR--ALDREQISNFTLVILCSD 1452
Score = 71.3 bits (167), Expect = 2e-10
Identities = 53/178 (29%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G + Y ++SGN+ F LD +G L LD E Q +L V
Sbjct: 1186 ITAHDPDEGRNGKVTYSILSGNENMTFMLDESSG--LLTTTCPLDYEMKTQ---HILTVL 1240
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P ++ + + +LD+ND P F+ Y S+ EN G V +V A D+D G
Sbjct: 1241 ALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGV 1300
Query: 338 NGEFTYQLDDPKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
N + +++ P +F + + S V T+LDRE ++V ++ PS+ T
Sbjct: 1301 NSKLQFEI-MPGASFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSST 1357
Score = 68.9 bits (161), Expect = 1e-09
Identities = 41/128 (32%), Positives = 71/128 (55%), Gaps = 11/128 (8%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F++D G + L K LD + + + L +Q S + + + + + +LD+NDN
Sbjct: 1938 FAIDQNTGVVVLVKTLDFE-----EMTEYELLIQIS---DSVHYTEGALVVRVLDVNDNP 1989
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL-T 362
P F DFY +++ E++P G+SVL + ATD + EN +Y++ FSIDP++G + T
Sbjct: 1990 PVFSQDFYQVTVPESIPVGYSVLTLSATDLESNEN--ISYRILSSSKEFSIDPKNGTIFT 2047
Query: 363 VRNQTVLD 370
+ +LD
Sbjct: 2048 ISPVLLLD 2055
Score = 68.5 bits (160), Expect = 1e-09
Identities = 115/480 (23%), Positives = 199/480 (41%), Gaps = 63/480 (13%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V +LD NDN PVF + Y+ ++ + VG + + A D + +N + Y + L+
Sbjct: 1980 VRVLDVNDNPPVF-SQDFYQVTVPESIPVGYSVLTLSATDLESNEN--ISYRI-----LS 2031
Query: 507 ITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I+P GT+ SP+L VEASD NP R +L + IE
Sbjct: 2032 SSKEFSIDPKNGTIFTI-SPVLLLDTISTTQFLVEASDG-GNPDLRALTLVEIGIEDMNN 2089
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSV---GQIRVNDAFEQNDVSYDLLHGYEEGVP 619
P+F Y + + +G+++ I + E V Y ++ G +
Sbjct: 2090 YA------PEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQN-N 2142
Query: 620 FAVE----------ERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVD 668
F VE ++ G + ++ L R ++ +A LS ++ V+D
Sbjct: 2143 FHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLD 2202
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDV 726
VND ++ HVKE++ +G H + S TG+ +I N +
Sbjct: 2203 VNDNPPNFSSLSYHT---HVKESTP---LGS--HITVVSANDRDTGSHAEIIYNIISGNE 2254
Query: 727 TDDIAIAED-GTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNP 784
+ E+ G ++ KPLD EK + +TV A + K S A ++ + + D+ND+
Sbjct: 2255 KGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEKKHFSFAVVF---VSVLDDNDHA 2311
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---------FGEGKE 835
P F +++ + EN I + I I A D D G Y++ +
Sbjct: 2312 PQFMFSSFSCIVPENLPISSTICS---INALDFDAGPYGELTYSIVSPCFLTHGMSYDHD 2368
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+F +D TG + LD E Y L++ A+D G ++ + + I ++ +P F Q
Sbjct: 2369 LFLIDPLTGDI-HAKQILDYENGNKYCLTVQAKDKGDATASLVVWVDIEGIDEFEPIFTQ 2427
Score = 67.3 bits (157), Expect = 3e-09
Identities = 111/465 (23%), Positives = 186/465 (40%), Gaps = 37/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + T+ D ND+ P F+ S+ Y+ + N + V+ V A D D G N V Y
Sbjct: 1354 LSSTTTILCTVEDENDHAPEFIVSS-YDIEVLENQEP-EVVYTVLASDMDAGNNRAVEYH 1411
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
+ + F IN +G +S + E L + SD P L V
Sbjct: 1412 IIDGNT---DECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRV 1468
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
++ + P P Y+ V + +GT V + D E + + E
Sbjct: 1469 LDAN----DHSPSFPTLY---YQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEA 1521
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA----LQENANLSIVTNATVHVVDVNDE 672
F ++ SG + + L R R + F AVA +Q + + +++ V+V DVND
Sbjct: 1522 SGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIK--VYVTDVNDN 1579
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
VL +P + S I + + NGT V F A Q +
Sbjct: 1580 DPVL---EQNPFDVFLSPESPTNQTTVIVRADDLDLGPNGT--VVFSFAETQSMFSIDKY 1634
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G I Q+ E ++ + + +G+ + + I++E E D F H Y
Sbjct: 1635 T--GEIQFQQNPSSEYFPIWLQLKVTD--QGIPARTTTGLLVIHMEGE-DVKISFSHHLY 1689
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+G + EN + GT I +KA D +++ Y++F G + + +G +
Sbjct: 1690 KGLVTENCEAGTSIV---TVKAFAPDSIQDSM-KYSIFSGNEDGVLSLCSKSGQLTVKEP 1745
Query: 852 S-LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
LD E + +L +V ++ G + ++ ++I DENDN P F Q
Sbjct: 1746 KFLDFEVRNEVQL-IVLAESSGHRAYCKVAVLIQDENDNSPCFEQ 1789
Score = 65.7 bits (153), Expect = 9e-09
Identities = 88/364 (24%), Positives = 156/364 (42%), Gaps = 34/364 (9%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I++ G V++ ++L E +E+ L I D + + V V V DVND+ PVF + +
Sbjct: 1938 FAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALV-VRVLDVNDNPPVFSQDF 1996
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-VLSVNGEL 1108
Y V E+ + + ATD + N N++Y I S + F I P G + +++ L
Sbjct: 1997 YQVTVPESIPVGYSVLTLSATDLE--SNENISYRILSSSKE--FSIDPKNGTIFTISPVL 2052
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
+T V A D G D+N+ +P+F L
Sbjct: 2053 LLDTISTTQFLVEASDGGNPDLRALTLVEIGIE-DMNNYAPEFTVKSYNLSLSEDALVGS 2111
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN-------GNGLILYSLPQR 1221
+ F ++ + T E + I F +T F + G ++L+SL +
Sbjct: 2112 TLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDRE 2171
Query: 1222 KNQQN--------LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VN 1271
+ + G P LSSTA++ + V DV D + P F S Y ++E+ +
Sbjct: 2172 ASASHELVILASDSGCPPLSSTAVISIQVLDVND-----NPPNFSSLSYHTHVKESTPLG 2226
Query: 1272 APVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ + +VS N + + ++ Y I++ N+ + F ++ G LYL++ D E + +
Sbjct: 2227 SHITVVSANDRDTGSHAEIIYNIISGNE---KGHFYLEENTGVLYLIKPLDYEKMTKFTL 2283
Query: 1332 IVRA 1335
V+A
Sbjct: 2284 TVQA 2287
Score = 63.7 bits (148), Expect = 4e-08
Identities = 96/428 (22%), Positives = 182/428 (42%), Gaps = 35/428 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLY 497
L + VE+ + D N+ P F + Y S+ +A VG+ + +D D +N V Y
Sbjct: 2074 LRALTLVEIGIEDMNNYAPEFTVKS-YNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEY 2132
Query: 498 DL---QRTSNLTITSPFKINP----NTGTVSVAESPILEGR--HALFVEASDQPANPSER 548
+ +N + + F + G + + S E H L + ASD P
Sbjct: 2133 SIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLS- 2191
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDV 606
S AV++I+V + P P+F Y V + +G+ + + ND ++
Sbjct: 2192 --STAVISIQVL--DVNDNP--PNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEI 2245
Query: 607 SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y+++ G E+G F +EE +GV+ ++ L + A V V
Sbjct: 2246 IYNIISGNEKG-HFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEKKHFSFAVVFVSV 2304
Query: 667 VDVNDERGVLLKGAHSPII-FHVKENSAGAAIGQIFHTNMSSIYGNGTGNV--RFLIANQ 723
+D ND + + S I+ ++ +S +I + + YG T ++ + +
Sbjct: 2305 LDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFD--AGPYGELTYSIVSPCFLTHG 2362
Query: 724 QDVTDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
D+ + + G I ++ LD E + Y +TV A+ +KG + + + V + IE +
Sbjct: 2363 MSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAK-DKGDATASLV--VWVDIEGID 2419
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
+ P+F Y + E +K + ++ ++A+DAD G + + +Y+L G F V++
Sbjct: 2420 EFEPIFTQDQYFFTLPEKNK---DRQLIGRVEASDADAGIDGVILYSL-GTSSPFFSVNK 2475
Query: 842 NTGVVKFI 849
G + I
Sbjct: 2476 TNGNIYLI 2483
Score = 62.1 bits (144), Expect = 1e-07
Identities = 89/363 (24%), Positives = 147/363 (40%), Gaps = 38/363 (10%)
Query: 47 DSPQNVVKFRLGCDFDEGDD---LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYH 103
D VV DF+E + L++I ++ L V V DVNDN P+F Y
Sbjct: 1941 DQNTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVL--DVNDNPPVFSQDFYQ 1998
Query: 104 VTVDELTPTGEKAFIFLIAPIGPSLTIPLTV----------PRGLTIFKDIRAFDRDKPN 153
VTV E P G + + I + P+ TIF D +
Sbjct: 1999 VTVPESIPVGYSVLTLSATDLESNENISYRILSSSKEFSIDPKNGTIFTISPVLLLDTIS 2058
Query: 154 TPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL 213
T +V +D G+ L + L L ++ D + + + + + ++ L
Sbjct: 2059 TTQF-----LVEASDGGNPDLRA-----LTLVEIGIEDMNNYAPEFTVKSYNLSLSEDAL 2108
Query: 214 FPEPIHA---IDQDLGVGAT-LRYELISGNDRKLFSLDS-VNGSLFLEKELD-LDAEHNL 267
+ ID D T + Y +ISGN + F +++ S + K++ L H+L
Sbjct: 2109 VGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSL 2168
Query: 268 QANTFV---LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS 324
L + AS P ++ A + I++LD+NDN P F Y+ + E+ P G
Sbjct: 2169 DREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSH 2228
Query: 325 VLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
+ V A D+D G + E Y + + KG F ++ +G L + LD E + + V
Sbjct: 2229 ITVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKP--LDYEKMTKFTLTVQ 2286
Query: 383 AKE 385
A +
Sbjct: 2287 ASD 2289
Score = 59.3 bits (137), Expect = 8e-07
Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
Query: 208 IHKEILFPEPIHAID--QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH 265
+++++ PI + + L + Y + SG+ FS+ G++ K LD H
Sbjct: 386 VYEDVPEDSPIGTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLD----H 441
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
Q VL VQA QL + + V I ++D+NDN P F I I + P G ++
Sbjct: 442 ETQP-VVVLTVQA-QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTAL 499
Query: 326 LQVMATDKDQGENGEFTYQLDDPK-GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
A D+D G NG Y + P+ G F+ID G L + + +L ++ +
Sbjct: 500 YLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQ 559
Query: 385 ETNP 388
+P
Sbjct: 560 GVHP 563
Score = 58.0 bits (134), Expect = 2e-06
Identities = 37/143 (25%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + Y ++SGN + F +D+++G + + LD + +++ L VQ
Sbjct: 1809 VFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTKAILDYEL-----TSSYSLIVQ 1863
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P + +++++ D+NDN P F + + I E+ G V V D D
Sbjct: 1864 ATDKGMPRLSNTTVIKVQVTDINDNAPAF-LPSEAVEITEDSLPGVIVTHVSVHDVDLNS 1922
Query: 338 NGEFTYQLD-DPKGAFSIDPRSG 359
F++ + +P F+ID +G
Sbjct: 1923 AFIFSFAKESNPGTKFAIDQNTG 1945
Score = 56.4 bits (130), Expect = 6e-06
Identities = 92/415 (22%), Positives = 165/415 (39%), Gaps = 48/415 (11%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E P+ + + A D D G N ++ Y +SE K+ A+ E++ +++ +
Sbjct: 854 EGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDY--- 910
Query: 1002 IVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+R+++ A D G L V + V ++ + + + + E
Sbjct: 911 --------RPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLK 962
Query: 1060 TRRVLGKVDATD-ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
+++ + ++D N L + I D D FEI TG L ++ ELD ET Y+
Sbjct: 963 PTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLF 1022
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
V+ D+ D ND+SP F DEL+ E N +
Sbjct: 1023 RVITTDHSKNLSLSSTVFLSIDVEDQNDHSPSFQ--DELIVISVEE-------NVPIGTL 1073
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
+ V+ A ++ + + + + + G LI S L S+ T IL
Sbjct: 1074 VYVFNAKDDDGSFLNSRIQYYIESHNP--GTNPFLIHPSFGTLVTVSRLDRESI-PTVIL 1130
Query: 1239 MVTVAD----VPDE-----------VEMSD-KPVFISRYYELEIEEN--VNAPVELVSLN 1280
VT +D V D ++++D P FIS + ++E+ V + V ++ +
Sbjct: 1131 TVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTFIS-FPNAHVKEDVTVGSLVHHITAH 1189
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ N K+ Y IL+ N+ TF++D +G L D E+K + + V A
Sbjct: 1190 DPDEGRNGKVTYSILSGNE---NMTFMLDESSGLLTTTCPLDYEMKTQHILTVLA 1241
Score = 56.0 bits (129), Expect = 7e-06
Identities = 47/157 (29%), Positives = 70/157 (44%), Gaps = 6/157 (3%)
Query: 999 GHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G++++ SL E+ L I A D G L+ + + V DVND+ P F Y+ +V
Sbjct: 2160 GYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHV 2219
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+E+ + V A D D G +A + Y I + F + TGVL + LD E
Sbjct: 2220 KESTPLGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMT 2279
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
K+ LTV A D D ND++P+F
Sbjct: 2280 KFTLTVQASD--AEKKHFSFAVVFVSVLDDNDHAPQF 2314
Score = 54.8 bits (126), Expect = 2e-05
Identities = 70/303 (23%), Positives = 127/303 (41%), Gaps = 21/303 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-- 124
LVR G G +S+ ++ +ED ND+ P F+ + Y + V E E + L + +
Sbjct: 1345 LVRDG-GFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLE-NQEPEVVYTVLASDMDA 1402
Query: 125 GPSLTIPLTVPRGLTI-FKDIRAFDRDKPNTPNSD----VHYSIVSGNDDGHFALESSHK 179
G + + + G T I + T D ++++V D SS
Sbjct: 1403 GNNRAVEYHIIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSS-- 1460
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISG 238
+ L +VLD + F + S R E+ + A+D+D G+ Y ++
Sbjct: 1461 VIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEY-FLTD 1519
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDA--EHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
F++D ++G+L LD +A +H A +Q S+ + +++ +
Sbjct: 1520 EASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVI------IKVYV 1573
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
D+NDN P E + +++ + P + + V A D D G NG + + + FSID
Sbjct: 1574 TDVNDNDPVLEQNPFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDK 1633
Query: 357 RSG 359
+G
Sbjct: 1634 YTG 1636
Score = 53.6 bits (123), Expect = 4e-05
Identities = 44/158 (27%), Positives = 72/158 (45%), Gaps = 20/158 (12%)
Query: 218 IHAIDQDLGVGATLRYELISG----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D D G+ + Y L G + F +D +G + + +++D + + T+
Sbjct: 79 VTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERD----PATYD 134
Query: 274 LQVQASQLNNPLKT----------AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
L V+A + T AQA V ++L D+NDN P F Y SI + G
Sbjct: 135 LLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGT 194
Query: 324 SVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
++ V+ATD+D G G Y+L + F+ID +G
Sbjct: 195 EIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTG 232
Score = 52.8 bits (121), Expect = 7e-05
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 21/166 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT ++ L+A+D D GLNGQ Y E F I+ G
Sbjct: 1487 VREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEA--------------SGAFTIDPMSG 1532
Query: 1000 HVIVARSLPPESEFRLNISALDG-----GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + +L E+ + SA+ G+ + + ++V+V DVND+ PV ++ ++ +
Sbjct: 1533 TLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFL 1592
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG 1100
T + V A D D G N + + ++T F I TG
Sbjct: 1593 SPESPTNQTTVIVRADDLDLGPNGTVVFSF--AETQSMFSIDKYTG 1636
Score = 52.8 bits (121), Expect = 7e-05
Identities = 98/407 (24%), Positives = 164/407 (40%), Gaps = 51/407 (12%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+I++ A DLDSGLNG I Y S LS + E F I+ G + L
Sbjct: 1806 VIQVFATDLDSGLNGLIEY----------SILSGNQEEA---FQIDALSGVITTKAILDY 1852
Query: 1010 E--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E S + L + A D G L++ ++V V D+ND+ P F + + E ++
Sbjct: 1853 ELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAFLPS-EAVEITEDSLPGVIVT 1911
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
V D D +A + F + S+ F I TGV+ + LD E +Y L + D+
Sbjct: 1912 HVSVHDVDL-NSAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDS 1970
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
DVNDN P F + + PE+ + SV+ +
Sbjct: 1971 ----VHYTEGALVVRVLDVNDNPPVF--SQDFYQVTVPESIPVG----YSVLTLSA--TD 2018
Query: 1186 IEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQ------RKNQQNLGLPSLSSTAIL 1238
+E N I ++ ++ +F I NG I P Q + + +
Sbjct: 2019 LESNENIS---YRILSSSKEFSIDPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLR 2075
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH---YENFKMRYYIL 1295
+T+ ++ E + P F + Y L + E+ LV+ + +H EN + Y I+
Sbjct: 2076 ALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSII 2135
Query: 1296 ---NENDTDIRRTFVID----PRNGTLYLVRSPDREVKDTYEVIVRA 1335
++N+ + F + G L L+ S DRE ++E+++ A
Sbjct: 2136 SGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILA 2182
Score = 51.2 bits (117), Expect = 2e-04
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
Query: 750 DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
D RMT +A KG +S +V + ED NDN PVF +TY I + ++ GTEI
Sbjct: 143 DEQRMTHLA-LVKGGLSAQAFVRVDL--EDVNDNHPVFNPSTYVTSISDETQPGTEI--I 197
Query: 810 NIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
N++ ATD D G Y L G +F +D TG+
Sbjct: 198 NVL-ATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGL 233
Score = 50.4 bits (115), Expect = 4e-04
Identities = 57/228 (25%), Positives = 91/228 (39%), Gaps = 34/228 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+IP+G +++ L+A DL+S N I Y L + F I+ ++G
Sbjct: 2001 VPESIPVGYSVLTLSATDLES--NENISYRI---------------LSSSKEFSIDPKNG 2043
Query: 1000 HVIVARS---LPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ L S + + A DGGN L V + ++D+N++ P F YN ++
Sbjct: 2044 TIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSL 2103
Query: 1055 EEAQYTRRVLGKVDATDADF-GQNANLTYFIQPSDTDLPFEIS----------PLTGVLS 1103
E L D D+ +N + Y I ++ F + G L
Sbjct: 2104 SEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLV 2163
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ LDRE + L ++A D+G DVNDN P F
Sbjct: 2164 LLHSLDREASASHELVILASDSG-CPPLSSTAVISIQVLDVNDNPPNF 2210
Score = 50.0 bits (114), Expect = 5e-04
Identities = 60/255 (23%), Positives = 107/255 (41%), Gaps = 24/255 (9%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLN 282
DL + Y ++S + K FS+D NG++F + L LD +T V+AS
Sbjct: 2018 DLESNENISYRILSSS--KEFSIDPKNGTIFTISPVLLLDT-----ISTTQFLVEASDGG 2070
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEF 341
NP A VEI + D+N+ PEF V YN+S+ E+ G +++ D D EN
Sbjct: 2071 NPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYV 2130
Query: 342 TYQL--DDPKGAFSIDPR----------SGWLTVRNQTVLDREAHSSLRMKVYAKETN-P 388
Y + + + F ++ + G+L + + LDREA +S + + A ++ P
Sbjct: 2131 EYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHS--LDREASASHELVILASDSGCP 2188
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
+ T S ++ P ++ T +G+ + D S +
Sbjct: 2189 PLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEIIYN 2248
Query: 449 LLDANDNNPVFVPSN 463
++ N+ ++ N
Sbjct: 2249 IISGNEKGHFYLEEN 2263
Score = 49.2 bits (112), Expect = 9e-04
Identities = 104/417 (24%), Positives = 157/417 (37%), Gaps = 49/417 (11%)
Query: 982 SADALEVKRYFV-INERHGHVIVARSLP----PESEFRLNISALDGGNLND--NISVRVF 1034
SAD RY + + G I+ +LP + L +SA DGG L N V +
Sbjct: 307 SADGEAAARYVANLAKILGEGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIH 366
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ F++ Y F V E +G V A + + + Y I D F
Sbjct: 367 IFQTTLAPAEFERPKYTFLVYEDVPEDSPIGTVKAREP-LNSSEPIFYRISSGDLGGKFS 425
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY-A 1153
I P G + LD ET+ +LTV A+ DVNDN P F
Sbjct: 426 IHPRLGTIRTRKPLDHETQPVVVLTVQAQLG--SAPACSSTEVNITVMDVNDNHPAFLRT 483
Query: 1154 FDEL-LEWKHP--EADELSNHNFESVMMIPVYKATIEENAP----IGTTVAKVFANDTDF 1206
DE+ + P A L+ + + +I P I + +F N +
Sbjct: 484 SDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGS-- 541
Query: 1207 IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEI 1266
+G G L +L R Q + A+L++TV V ++ E S F Y++E+
Sbjct: 542 LGAGEQREL-TLTLRAEDQGVH----PQAALLVLTV--VIEKREHSPSWTFEHLVYQVEV 594
Query: 1267 EENVNAPVELVSLN---LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
E+++ +++ L +RY + D+ + F I P G +YL R D
Sbjct: 595 SESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAM---FGIRPYTGWIYLRRQFDY 651
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
E TY V A + ED + V+VR+ D NDNSP F
Sbjct: 652 ESTQTYNFRVFAW--------------IPEDGF--LQNVSTTVIVRVWDENDNSPTF 692
Score = 48.4 bits (110), Expect = 0.002
Identities = 65/275 (23%), Positives = 114/275 (41%), Gaps = 23/275 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL- 499
S V +T++D NDN+P F+ ++ E + GT + +A D D G+NG++ Y +
Sbjct: 462 SSTEVNITVMDVNDNHPAFLRTS-DEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIA 520
Query: 500 -QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ I + G++ E L L + A DQ +P + +L V+T+
Sbjct: 521 SPQPGVFAIDRALGVLFLNGSLGAGEQREL----TLTLRAEDQGVHP---QAALLVLTVV 573
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ + + + P F Y+ V ++ T + Q + + Q S L + E V
Sbjct: 574 IEK--REHSPSW-TFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAAS-PLRYSLEPSV 629
Query: 619 P---FAVEERSGVITVVDDLSRYNRPMYDFEAVA-LQENANL-SIVTNATVHVVDVNDER 673
F + +G I + + Y+F A + E+ L ++ T V V D ND
Sbjct: 630 DSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNS 689
Query: 674 GVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSS 707
L H + V+E+ IG+I +M S
Sbjct: 690 PTFL---HDVLFLKVEESPVPQGVIGKITAIDMDS 721
Score = 48.0 bits (109), Expect = 0.002
Identities = 31/97 (31%), Positives = 46/97 (47%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
E R+ AL G L+ VRV ++DVND+ PVF + Y ++ + + V ATD
Sbjct: 144 EQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATD 203
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
D G + Y + P + F I TG+ S E+
Sbjct: 204 QDSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEVEI 240
Score = 46.8 bits (106), Expect = 0.005
Identities = 32/77 (41%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V L D NDN+PVF PS Y S+ + GT I V A D D G G V Y+L +
Sbjct: 163 VRVDLEDVNDNHPVFNPST-YVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGN- 220
Query: 505 LTITSPFKINPNTGTVS 521
++S F I+ TG S
Sbjct: 221 --VSSLFTIDSTTGLYS 235
Score = 45.6 bits (103), Expect = 0.011
Identities = 48/199 (24%), Positives = 82/199 (41%), Gaps = 15/199 (7%)
Query: 205 GKRIHKEILFPEPIHAI-------DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEK 257
GK +H ++L +P++ + D D G A + Y + S + F +D+ NG +
Sbjct: 845 GKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTT 904
Query: 258 ELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE 317
L D ++ + V A+ P QA V I+++ L+ + ++ I E
Sbjct: 905 ILSYD-----YRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPE 959
Query: 318 NL-PNGFSVLQVMATDKDQGENGE--FTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
NL P L + Q NG+ F+ DD G F ID +G L + + + +H
Sbjct: 960 NLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSH 1019
Query: 375 SSLRMKVYAKETNPSVVGT 393
R+ N S+ T
Sbjct: 1020 YLFRVITTDHSKNLSLSST 1038
Score = 45.2 bits (102), Expect = 0.014
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 15/150 (10%)
Query: 218 IHAIDQDLGVGATLRYELIS--------GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQA 269
I+A+D D G L Y ++S D LF +D + G + ++ LD +
Sbjct: 2336 INALDFDAGPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYE-----NG 2390
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
N + L VQA + + V+IE +D + P F D Y ++ E + + +V
Sbjct: 2391 NKYCLTVQAKDKGDATASLVVWVDIEGIDEFE--PIFTQDQYFFTLPEKNKDRQLIGRVE 2448
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
A+D D G +G Y L FS++ +G
Sbjct: 2449 ASDADAGIDGVILYSLGTSSPFFSVNKTNG 2478
Score = 41.1 bits (92), Expect = 0.23
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 10/170 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLG T+ + + +FS+D G E+ + + LQ++
Sbjct: 1605 VRADDLDLGPNGTVVFSF--AETQSMFSIDKYTG------EIQFQQNPSSEYFPIWLQLK 1656
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ P +T + I + + D F Y + EN G S++ V A D +
Sbjct: 1657 VTDQGIPARTTTGLLVIHM-EGEDVKISFSHHLYKGLVTENCEAGTSIVTVKAFAPDSIQ 1715
Query: 338 NG-EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ +++ + G S+ +SG LTV+ LD E + +++ V A+ +
Sbjct: 1716 DSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESS 1765
Score = 39.1 bits (87), Expect = 0.92
Identities = 19/40 (47%), Positives = 24/40 (60%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKEL 259
A DQD G+ T+ YELI GN LF++DS G E E+
Sbjct: 201 ATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEVEI 240
Score = 39.1 bits (87), Expect = 0.92
Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 9/184 (4%)
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
I +G I+ PL + + V A+ G+ + VTI+I P FE
Sbjct: 323 ILGEGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINA-DVTIHIFQTTLAPAEFERPK 381
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + E+ + I +KA + + +F G+ F + G ++
Sbjct: 382 YTFLVYEDVPEDSPI---GTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIR-TRK 437
Query: 852 SLDREKKIMYKLSLVAR-DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LD E + + L++ A+ + S E+ I + D NDN P F + + ++RI + T
Sbjct: 438 PLDHETQPVVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAF--LRTSDEIRISQTTP- 494
Query: 911 NGTA 914
GTA
Sbjct: 495 PGTA 498
Score = 38.3 bits (85), Expect = 1.6
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDA 1483
A D D G+N Y + +E + F IDP+SGT++ L R+A
Sbjct: 1502 AVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLKTSNTLDREA 1544
Score = 37.9 bits (84), Expect = 2.1
Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 19/101 (18%)
Query: 812 IKATDADEGTNALFMYTLFG-----EGKEMFDVDENTGVVKFIGDSLDREKK-IMYKLSL 865
+ A+DAD G Y+L+ E + F +D + G + + +DRE+ Y L +
Sbjct: 79 VTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQI-CVSQDIDRERDPATYDLLV 137
Query: 866 VARD------------TGGLSSEAELIIMIGDENDNKPEFN 894
A+D GGLS++A + + + D NDN P FN
Sbjct: 138 EAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFN 178
Score = 37.1 bits (82), Expect = 3.7
Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 8/113 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+++ SF V V++LD ND+ P F+ S+ + + N + + I + A+D D G G +
Sbjct: 2291 EKKHFSFAVVFVSVLDDNDHAPQFMFSS-FSCIVPENLPISSTICSINALDFDAGPYGEL 2349
Query: 496 LYDLQRTSNLTITSP-----FKINPNTGTVSVAESPILE--GRHALFVEASDQ 541
Y + LT F I+P TG + + E ++ L V+A D+
Sbjct: 2350 TYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDK 2402
Score = 35.9 bits (79), Expect = 8.6
Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 156 NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
N +H+SIV+ + DGHF ++SS L L K LDY+
Sbjct: 981 NGKLHFSIVADDKDGHFEIDSSTGD-LFLSKELDYE 1015
>UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia
californica|Rep: Cadherin-related protein - Aplysia
californica (California sea hare)
Length = 1172
Score = 120 bits (290), Expect = 2e-25
Identities = 124/472 (26%), Positives = 204/472 (43%), Gaps = 35/472 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V + + D NDN P F PS + + N VG A+D D GQN + Y L
Sbjct: 150 VVVNINITDINDNMPTFKPSEI-TLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEP 208
Query: 503 SN-LTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIE 558
S ++ ++N VA++ + L+G + L V A D A PS +T+
Sbjct: 209 SGPFSLDVERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGA-PS----LTGTMTVH 263
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEE 616
V + P F Y + VG +G VG++ D + DV Y L+ ++
Sbjct: 264 VN--VTDENDNSPVFTQEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKD 321
Query: 617 ---GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVND 671
G FAVE+ +G IT+ L Y+ V ++ +++ +T A ++ +V+V +
Sbjct: 322 QRGGELFAVEQLTGEITIKAPLE-YDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGN 380
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAA----IGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
L + + S GA +G++ T+ +G V+ A+ T
Sbjct: 381 NAPRLSITLQKTVRANTVRISEGARNKTFVGKLTATDNDP---GDSGKVQCHSAHPNFQT 437
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I + TI LDRE++D +T++ + G + + D NDNPP F
Sbjct: 438 NRIG-PHEFTIIMNGTLDRERQDTIDVTLVCS-DAGAPRKTSSSSFRVVVTDVNDNPPRF 495
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
TY + E + +G I ++A D D G N F Y+LF + ++F +D G++
Sbjct: 496 SQETYVVNVTEENIVGKHILK---LRAEDPDYGVNKEFSYSLFPKENDVFGIDSKDGILT 552
Query: 848 FIGDSLDR--EKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+ D E+K+ ++ R T L S A +++ I D NDN PE E
Sbjct: 553 -ARTTFDHELERKVNVIVTATDRGTPSLVSTATVVVNILDINDNYPELTTTE 603
Score = 85.8 bits (203), Expect = 8e-15
Identities = 122/466 (26%), Positives = 191/466 (40%), Gaps = 64/466 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN +G T A+D D+G N Y + PS +L+V+R +N R
Sbjct: 175 IPENNAVGLTKPLPTAMDRDTGQNSVQHYTL-----LEPS--GPFSLDVERR--LNNRFR 225
Query: 1000 HVIVA-RSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+VA SL E + + L + A DGG +L ++V V V D ND+ PVF + Y+++V
Sbjct: 226 LSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNSPVFTQEEYSYSV 285
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP----FEISPLTGVLSVNGELDR 1110
E + V+GK+ ATD D G+NA++ Y + S D F + LTG +++ L+
Sbjct: 286 GETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQLTGEITIKAPLEY 345
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
+ + V ARD G +V +N+P+ L + +S
Sbjct: 346 DAGSTFSAVVEARDRG-DIARLTEARLSLSIVNVGNNAPRLSI--TLQKTVRANTVRISE 402
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG-----LILYSLPQRKNQQ 1225
V K T +N P + + + +F N G +I+ R+ Q
Sbjct: 403 GARNKTF---VGKLTATDNDPGDSGKVQCHSAHPNFQTNRIGPHEFTIIMNGTLDRERQD 459
Query: 1226 NL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
+ G P +S++ V V DV D + P F Y + + E +
Sbjct: 460 TIDVTLVCSDAGAPRKTSSSSFRVVVTDVND-----NPPRFSQETYVVNVTEENIVGKHI 514
Query: 1277 VSLNLTE-HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ L + Y K Y L + D+ F ID ++G L + D E++ VIV A
Sbjct: 515 LKLRAEDPDYGVNKEFSYSLFPKENDV---FGIDSKDGILTARTTFDHELERKVNVIVTA 571
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
R P ++ VVV I D+NDN P+ T
Sbjct: 572 T----DRGTPSLVSTAT-------------VVVNILDINDNYPELT 600
Score = 81.8 bits (193), Expect = 1e-13
Identities = 116/469 (24%), Positives = 189/469 (40%), Gaps = 33/469 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V + D NDN+PVF Y +S+ +VG V+GK+ A D DLG+N V Y
Sbjct: 256 LTGTMTVHVNVTDENDNSPVFTQEE-YSYSVGETERVGEVVGKLTATDVDLGKNADVRYS 314
Query: 499 L-QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF---VEASDQP--ANPSERRYSL 552
L T + F + TG +++ ++P+ + F VEA D+ A +E R SL
Sbjct: 315 LIFSTKDQRGGELFAVEQLTGEITI-KAPLEYDAGSTFSAVVEARDRGDIARLTEARLSL 373
Query: 553 AVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
++V + G + I + T VG++ D +
Sbjct: 374 SIVNV----GNNAPRLSITLQKTVRANTVRISEGARNKTFVGKLTATDNDPGDSGKVQCH 429
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVDVN 670
+ + I + L R + D V A +++ V V DVN
Sbjct: 430 SAHPNFQTNRIGPHEFTIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVN 489
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + ++ +EN G I ++ + YG L + DV
Sbjct: 490 DNPPRFSQETY--VVNVTEENIVGKHILKLRAEDPD--YGVNKEFSYSLFPKENDVFG-- 543
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
++DG + + D E + V A ++G S V + I D NDN P E
Sbjct: 544 IDSKDGILTARTTFDHELERKVNVIVTAT-DRGTPSLVSTATVVVNILDINDNYP--ELT 600
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVK 847
T E + E G ++ + ++ TD D G NA ++++ +MF VD + V
Sbjct: 601 TTELRVPEE---GGKMMLVGTLEGTDKDSGRNARLIFSMPPTSDITGQMFKVDPDGRV-- 655
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSS--EAELIIMIGDENDNKPEFN 894
F +LDRE + Y LS+ RD G + +++ D ND+ P F+
Sbjct: 656 FAIQNLDRESRSFYSLSIELRDDGVEPKVVYGTVNVIVEDVNDHAPSFH 704
Score = 74.1 bits (174), Expect = 3e-11
Identities = 151/664 (22%), Positives = 257/664 (38%), Gaps = 94/664 (14%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V I I D NDN P F+ + I EN+ +G + A D D G N++ YTL E
Sbjct: 152 VNINITDINDNMPTFKPSEITLDIPENNAVGLTKPLPT---AMDRDTGQNSVQHYTLL-E 207
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
F +D ++R ++LSLVA + + +++ E+ P
Sbjct: 208 PSGPFSLD------------VERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPS 255
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
+ +H + V +N + Q + + E +G + K
Sbjct: 256 LT-----GTMTVH-------------VNVTDENDNSPVFTQEEYSYSVGETERVGEVVGK 297
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE-- 1010
L A D+D G N +RY S ++ + + F + + G + + L +
Sbjct: 298 LTATDVDLGKNADVRY---SLIFSTKDQRGGEL------FAVEQLTGEITIKAPLEYDAG 348
Query: 1011 SEFRLNISALDGGNLNDNISVRVFVKDVN--DHFP----VFKKTWY--NFNVEEAQYTRR 1062
S F + A D G++ R+ + VN ++ P +KT + E +
Sbjct: 349 STFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTVRANTVRISEGARNKT 408
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+GK+ ATD D G + + + I P + +NG LDRE +D +T+V
Sbjct: 409 FVGKLTATDNDPGDSGKVQCHSAHPNFQTN-RIGPHEFTIIMNGTLDRERQDTIDVTLVC 467
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
D G DVNDN P+F E E + + H + P Y
Sbjct: 468 SDAG-APRKTSSSSFRVVVTDVNDNPPRF--SQETYVVNVTEENIVGKHILKLRAEDPDY 524
Query: 1183 KATIEENAPIGTTVAKVFANDT-DFIGNGNGLILYSLPQRKN----QQNLGLPSLSSTAI 1237
E + + VF D+ D I + L ++ N + G PSL STA
Sbjct: 525 GVNKEFSYSLFPKENDVFGIDSKDGILTARTTFDHELERKVNVIVTATDRGTPSLVSTAT 584
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNE 1297
++V + D+ D + P + EL + E + + +L T+ R
Sbjct: 585 VVVNILDIND-----NYPELTTT--ELRVPEEGGKMMLVGTLEGTDKDSGRNARLIFSMP 637
Query: 1298 NDTDIR-RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVL 1356
+DI + F +DP +G ++ +++ DRE + Y + + + +D +
Sbjct: 638 PTSDITGQMFKVDP-DGRVFAIQNLDRESRSFYSLSIE----------------LRDDGV 680
Query: 1357 EGMTKYDVKVVVRIKDVNDNSPKF---TNGNRPL--VTAIPTTAPFGYQVMQLKGAIGHH 1411
E Y V V ++DVND++P F T N+ + V ++PT P ++ G G +
Sbjct: 681 EPKVVYGT-VNVIVEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPI-TRLNATDGDAGEN 738
Query: 1412 PTAS 1415
T S
Sbjct: 739 QTIS 742
Score = 63.7 bits (148), Expect = 4e-08
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 4/126 (3%)
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+T + + S P KT+ + + + D+NDN P F + Y +++ E G +L++
Sbjct: 459 DTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVTEENIVGKHILKLR 518
Query: 330 ATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-N 387
A D D G N EF+Y L F ID + G LT R T D E + + V A +
Sbjct: 519 AEDPDYGVNKEFSYSLFPKENDVFGIDSKDGILTAR--TTFDHELERKVNVIVTATDRGT 576
Query: 388 PSVVGT 393
PS+V T
Sbjct: 577 PSLVST 582
Score = 62.1 bits (144), Expect = 1e-07
Identities = 95/423 (22%), Positives = 172/423 (40%), Gaps = 35/423 (8%)
Query: 469 MKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPIL 528
+ A+ T +GK+ A D D G +G V + T +I P+ T+ + +
Sbjct: 400 ISEGARNKTFVGKLTATDNDPGDSGKVQCHSAHPNFQTN----RIGPHEFTIIMNGTLDR 455
Query: 529 EGRHALFVE--ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNV 586
E + + V SD A S VV +V + P P F Y V
Sbjct: 456 ERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVN-----DNP--PRFSQETYVVNVTEEN 508
Query: 587 GIGTSVGQIRVNDA-FEQN-DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
+G + ++R D + N + SY L +E F ++ + G++T +
Sbjct: 509 IVGKHILKLRAEDPDYGVNKEFSYSLFP--KENDVFGIDSKDGILTARTTFDHELERKVN 566
Query: 645 FEAVALQENANLSIVTNATV--HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
V + S+V+ ATV +++D+ND L + + +E +G +
Sbjct: 567 V-IVTATDRGTPSLVSTATVVVNILDINDNYPELT----TTELRVPEEGGKMMLVGTLEG 621
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDI-AIAEDGTIFTQKPLDREKRDVYRMTVIAEFN 761
T+ S + F + D+T + + DG +F + LDRE R Y +++ E
Sbjct: 622 TDKDS---GRNARLIFSMPPTSDITGQMFKVDPDGRVFAIQNLDRESRSFYSLSI--ELR 676
Query: 762 KGVISGAGIY-QVTIYIEDENDNPPVFEHATYEGFIMENS-KIGTEIKMDNIIKATDADE 819
+ +Y V + +ED ND+ P F T + + + T + + + ATD D
Sbjct: 677 DDGVEPKVVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITR-LNATDGDA 735
Query: 820 GTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
G N Y +F G+ ++F ++++TG + F+ + + L + A D G E++
Sbjct: 736 GENQTISYYIFSGDKTDLFRLEKDTGNL-FLRRKVKATDDQLQTLMVAAHDWGVDQQESQ 794
Query: 879 LII 881
I
Sbjct: 795 TFI 797
Score = 57.6 bits (133), Expect = 2e-06
Identities = 52/180 (28%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D GV Y L + +F +DS +G L D H L+ V+ V
Sbjct: 517 LRAEDPDYGVNKEFSYSLFP-KENDVFGIDSKDGILTARTTFD----HELERKVNVI-VT 570
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ P + A V + +LD+NDN PE + + E V + TDKD G
Sbjct: 571 ATDRGTPSLVSTATVVVNILDINDNYPELTTT--ELRVPEEGGKMMLVGTLEGTDKDSGR 628
Query: 338 NGEFTYQL---DDPKG-AFSIDPRSGWLTVRNQTVLDREAHS--SLRMKVYAKETNPSVV 391
N + + D G F +DP ++N LDRE+ S SL +++ P VV
Sbjct: 629 NARLIFSMPPTSDITGQMFKVDPDGRVFAIQN---LDRESRSFYSLSIELRDDGVEPKVV 685
Score = 56.8 bits (131), Expect = 4e-06
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD---SVNGSLFLEKELDLDAEHNLQANTFVLQV 276
A+D+D G + Y L+ + FSLD +N L D + LQ + + L V
Sbjct: 190 AMDRDTGQNSVQHYTLLEPSGP--FSLDVERRLNNRFRLSLVADASLDRELQGH-YTLLV 246
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P T V + + D NDN P F + Y+ S+ E G V ++ ATD D G
Sbjct: 247 VAEDGGAPSLTGTMTVHVNVTDENDNSPVFTQEEYSYSVGETERVGEVVGKLTATDVDLG 306
Query: 337 ENGEFTYQL----DDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+N + Y L D +G F+++ +G +T++ L+ +A S+ V A++
Sbjct: 307 KNADVRYSLIFSTKDQRGGELFAVEQLTGEITIK--APLEYDAGSTFSAVVEARD 359
Score = 52.0 bits (119), Expect = 1e-04
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 6/108 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V I + D+NDN+P F+ + I EN G + A D+D G+N Y L +P G
Sbjct: 152 VNINITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSGP 211
Query: 352 FSIDPRSGW-----LTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
FS+D L++ LDRE + V A++ PS+ GT
Sbjct: 212 FSLDVERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGT 259
Score = 51.2 bits (117), Expect = 2e-04
Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 18/169 (10%)
Query: 220 AIDQDLGVGATLRYELI-SGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
A D DLG A +RY LI S D++ LF+++ + G + ++ L+ DA +TF
Sbjct: 300 ATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQLTGEITIKAPLEYDA-----GSTFSAV 354
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY------NISIVENLPNGFSVLQVM 329
V+A + + +AR+ + ++++ +N P + + I E N V ++
Sbjct: 355 VEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTVRANTVRISEGARNKTFVGKLT 414
Query: 330 ATDKDQGENGEFTYQLDDPKGAFS-IDPRSGWLTVRNQTVLDREAHSSL 377
ATD D G++G+ P + I P T+ LDRE ++
Sbjct: 415 ATDNDPGDSGKVQCHSAHPNFQTNRIGPHE--FTIIMNGTLDRERQDTI 461
Score = 48.8 bits (111), Expect = 0.001
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 6/128 (4%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPS 1087
+ V + + D+ND+ P FK + ++ E A D D GQN+ Y ++PS
Sbjct: 150 VVVNINITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPS 209
Query: 1088 ---DTDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
D+ ++ + L + LDRE + Y L VVA D G D
Sbjct: 210 GPFSLDVERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGG-APSLTGTMTVHVNVTD 268
Query: 1144 VNDNSPKF 1151
NDNSP F
Sbjct: 269 ENDNSPVF 276
Score = 46.4 bits (105), Expect = 0.006
Identities = 53/182 (29%), Positives = 80/182 (43%), Gaps = 21/182 (11%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
L D DSG N ++ + P S ++ +V + G V ++L ES
Sbjct: 619 LEGTDKDSGRNARLIFSMP-----PTSDITGQMFKV-------DPDGRVFAIQNLDRESR 666
Query: 1013 --FRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFK-KTWYNFNVEEAQY--TRRVLG 1065
+ L+I D G + +V V V+DVNDH P F T N V T +
Sbjct: 667 SFYSLSIELRDDGVEPKVVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPIT 726
Query: 1066 KVDATDADFGQNANLTYFIQPSD-TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+++ATD D G+N ++Y+I D TDL F + TG L + ++ + L V A D
Sbjct: 727 RLNATDGDAGENQTISYYIFSGDKTDL-FRLEKDTGNLFLRRKVKATDDQLQTLMVAAHD 785
Query: 1125 NG 1126
G
Sbjct: 786 WG 787
Score = 45.2 bits (102), Expect = 0.014
Identities = 78/346 (22%), Positives = 137/346 (39%), Gaps = 28/346 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
LV AG + ++ S V + DVNDN P F Y V V E G+ I + P
Sbjct: 465 LVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVTEENIVGKH--ILKLRAEDP 522
Query: 127 SLTIPLTVPRGLTIFK-DIRAFD-RDKPNTPNSDVHYS-------IVSGNDDGHFALESS 177
+ L + D+ D +D T + + IV+ D G +L S+
Sbjct: 523 DYGVNKEFSYSLFPKENDVFGIDSKDGILTARTTFDHELERKVNVIVTATDRGTPSLVST 582
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
V+ +LD + E + + K +L + D+D G A L + +
Sbjct: 583 ATVVV---NILDINDNYPELTTTELRVPEEGGKMMLVGT-LEGTDKDSGRNARLIFSMPP 638
Query: 238 GND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
+D ++F +D +G +F + LD ++ + + L ++ K V +
Sbjct: 639 TSDITGQMFKVDP-DGRVFAIQNLDRESR-----SFYSLSIELRDDGVEPKVVYGTVNVI 692
Query: 296 LLDLNDNLPEFEVDF---YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKG 350
+ D+ND+ P F +S V +LP + ++ ATD D GEN +Y + D
Sbjct: 693 VEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITRLNATDGDAGENQTISYYIFSGDKTD 752
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
F ++ +G L +R + + +L + + + TF D
Sbjct: 753 LFRLEKDTGNLFLRRKVKATDDQLQTLMVAAHDWGVDQQESQTFID 798
Score = 37.9 bits (84), Expect = 2.1
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
Query: 1441 ATDSDIGINADIRYQIL-----NEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
ATD D+G NAD+RY ++ FA++ ++G + + A L DAG F
Sbjct: 300 ATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQLTGEITIKAPLEYDAGSTF 351
>UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-PA -
Drosophila melanogaster (Fruit fly)
Length = 1706
Score = 120 bits (288), Expect = 4e-25
Identities = 123/453 (27%), Positives = 194/453 (42%), Gaps = 30/453 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+++ V L D NDN P + ++ ++ +V A D D G N +V Y +
Sbjct: 484 LSLTVHLRDVNDNAPKLAMVAPISITAGDQSE-SRLVTQVTATDNDEGPNAVVTYSIYHV 542
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
SN I F IN TG + + ++++ V+A+D S+ A+V + VT G
Sbjct: 543 SNNGIQK-FTINATTGEIRTQGRLLAGEQYSITVQATDIGGLSSQ-----AIVEVSVTPG 596
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
KP P F YE V I ++V + D E + V Y ++ G + FAV
Sbjct: 597 PN-TKP--PRFQKPIYEVQVSEGAEINSTVTVVHAEDP-ENDAVVYSIISGNDLR-QFAV 651
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+ SGVI V+ L R + Y A ++ LS + V D+ND+ + +
Sbjct: 652 GQESGVIIVIRKLDRESLTRYQLILKA-EDTGGLSSSATVNIKVTDINDKNPEF-EASTL 709
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
P +F V+E A A++G + T+ G N + D+ I A G I T K
Sbjct: 710 PYVFQVEEGKAQASVGVVHATDADE----GI-NAEITYSIPTDIPFTIN-ATSGEILTAK 763
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LD E+ + Y+ V A+ + + G VT+ + D D P F A + I EN
Sbjct: 764 ELDYEQLNEYKFVVTAK-DGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENE-- 820
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
E + ++A D D Y L E+F V E +G V+ I LD E + ++
Sbjct: 821 --ENFLVATVQAFDPDSMPE--ITYVLRKGNAELFKVSEKSGEVRTI-KGLDYESQKQHQ 875
Query: 863 LSL--VARDTGGLSSEAELIIMIGDENDNKPEF 893
L++ + D G L++ + D ND P F
Sbjct: 876 LTIGTIENDGNGPGDTILLVVDVEDRNDLPPRF 908
Score = 98.7 bits (235), Expect = 1e-18
Identities = 165/662 (24%), Positives = 271/662 (40%), Gaps = 62/662 (9%)
Query: 249 VNGS-LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
+NG L L + LD D E NL + V QV + + K + + + D+NDN P F
Sbjct: 88 LNGKKLQLLQPLDRD-EENL--SHIVFQVSCTTRSTGKKRT-IPIIVRVSDINDNAPRFM 143
Query: 308 VDFYNISIVENLPNGFSVLQ-VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
Y +++ E+ P G ++ + + A DKD G NG Y + + P S N
Sbjct: 144 NTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEYFIAEG------SPNS-----TNV 192
Query: 367 TVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVG 426
+ + + + + + +V T D ++I + + ++ + T
Sbjct: 193 EKYSADGYGTFAIS-FPHQGQVTVAKTL-DFEKIQTYYLTIVASDR--ARNTADRLSSTT 248
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG--TVI-GKVK 483
T T NI ++ SF+ LD NP Y S+ + + +G TV+ +++
Sbjct: 249 TLTVNIADSNDLDPSFIYSGCVSLDGACINPE------YSASVPAGSLLGVLTVLPERIQ 302
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPA 543
AVD D N + Y F+I+ +TG + ++ + +
Sbjct: 303 AVDLDT-INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEV 361
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN----- 598
+P +R++ A + I V + N P I + E +V N IGT V N
Sbjct: 362 SPGPQRFTTAKLEIFV-KPVDANPPVI---SSSQAEGYVDENSPIGTRVLDAHGNPISFM 417
Query: 599 --DA-FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP---MYDFEAVALQE 652
DA +D D + YE P G++ V ++ + P + F+ VA +
Sbjct: 418 TTDADLSDSDPKPDYI--YELTTPSFNVTGDGILVVNEENLDRDPPAPGRFKFQVVAREP 475
Query: 653 NAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN 711
N S + TVH+ DVND L A PI + S + Q+ T+ + N
Sbjct: 476 RTNAASAPLSLTVHLRDVNDNAPKLAMVA--PISITAGDQSESRLVTQVTATD-NDEGPN 532
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
+ + A G I TQ L ++ Y +TV A + G +S I
Sbjct: 533 AVVTYSIYHVSNNGIQKFTINATTGEIRTQGRLLAGEQ--YSITVQAT-DIGGLSSQAIV 589
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+V++ N PP F+ YE + E ++I + + ++ A D + +A+ + G
Sbjct: 590 EVSV-TPGPNTKPPRFQKPIYEVQVSEGAEINSTV---TVVHAEDPE--NDAVVYSIISG 643
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
F V + +GV+ I LDRE Y+L L A DTGGLSS A + I + D ND P
Sbjct: 644 NDLRQFAVGQESGVIIVI-RKLDRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNP 702
Query: 892 EF 893
EF
Sbjct: 703 EF 704
Score = 87.4 bits (207), Expect = 3e-15
Identities = 64/182 (35%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Query: 990 RYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
R F + + G +IV R L ES ++L + A D G L+ + +V + V D+ND P F+
Sbjct: 647 RQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEA 706
Query: 1048 TW--YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ Y F VEE + V G V ATDAD G NA +TY I TD+PF I+ +G +
Sbjct: 707 STLPYVFQVEEGKAQASV-GVVHATDADEGINAEITYSIP---TDIPFTINATSGEILTA 762
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
ELD E ++Y V A+D G D+ D PKF D ++ PE
Sbjct: 763 KELDYEQLNEYKFVVTAKD-GAPDARLGTASVTVMVLDLPDEVPKF--SDARIDVHIPEN 819
Query: 1166 DE 1167
+E
Sbjct: 820 EE 821
Score = 87.0 bits (206), Expect = 3e-15
Identities = 117/452 (25%), Positives = 192/452 (42%), Gaps = 44/452 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S VEV++ + P +YE + A++ + + V A DP+ N V+Y
Sbjct: 583 LSSQAIVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPE---NDAVVYS 639
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
+ ++L F + +G + V E R+ L ++A D S A V
Sbjct: 640 IISGNDLR---QFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGGLSSS-----ATVN 691
Query: 557 IEVTRGTKGNKPDIPDFMGA--PYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
I+VT N P+F + PY F V SVG + DA E ++ ++ +
Sbjct: 692 IKVTDINDKN----PEFEASTLPYVFQVEEGKA-QASVGVVHATDADE--GINAEITYSI 744
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDER 673
+PF + SG I +L Y F A + + T + TV V+D+ DE
Sbjct: 745 PTDIPFTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDE- 803
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ K + + I H+ EN + + + S+ + +++ ++
Sbjct: 804 --VPKFSDARIDVHIPENEENFLVATVQAFDPDSM-----PEITYVLRKGNAELFKVS-E 855
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G + T K LD E + +++T+ N G G I V + +ED ND PP F
Sbjct: 856 KSGEVRTIKGLDYESQKQHQLTIGTIENDGNGPGDTILLV-VDVEDRNDLPPRFITVPDP 914
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNA--LFMYTLFGEGK--EMFDVDENTGVVKFI 849
+ ++ IGT I + A D D GT+ + Y + G GK + F VD +TG V+ I
Sbjct: 915 VTVNDDQGIGTIIA---TLPAIDGD-GTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVR-I 969
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAEL 879
D L +E+ Y++ + A D G LSS A L
Sbjct: 970 RDELRKEEDTEYQVDIRAYDLGEPQLSSVAPL 1001
Score = 83.0 bits (196), Expect = 6e-14
Identities = 159/638 (24%), Positives = 251/638 (39%), Gaps = 98/638 (15%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
+PLDR++ ++ + + + + D NDN P F + YE + E++
Sbjct: 97 QPLDRDEENLSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFMNTPYEVTVPESTP 156
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGK------EMFDVD-ENTGVVKF------ 848
+GT I + I+A D D G N L Y EG E + D T + F
Sbjct: 157 VGTTIFRN--IQALDKDAGVNGLVEY-FIAEGSPNSTNVEKYSADGYGTFAISFPHQGQV 213
Query: 849 -IGDSLDREKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ +LD EK Y L++VA D LSS L + I D ND P F I
Sbjct: 214 TVAKTLDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADSNDLDPSF--IYSGC-- 269
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQ-LGPLFLIPENIPIGTTIIKLNALDLDSG 961
L+G + P+ ++ LG L ++PE ++ A+DLD+
Sbjct: 270 -----VSLDGAC------INPEYSASVPAGSLLGVLTVLPE---------RIQAVDLDT- 308
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI---- 1017
+N IRY F S + P AD YF I+E G + +++ + + +I
Sbjct: 309 INSPIRYSFASGM---PGNY-AD------YFQIDESTGVLKQTKAVDTSTAKKYDIIVKA 358
Query: 1018 -SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE-AQYTRRVLG------KVDA 1069
G + +FVK V+ + PV + V+E + RVL
Sbjct: 359 EEVSPGPQRFTTAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMT 418
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE-LDRE--TEDKYILTVVARDNG 1126
TDAD + +I T F ++ G+L VN E LDR+ ++ VVAR+
Sbjct: 419 TDADLSDSDPKPDYIYELTTP-SFNVTG-DGILVVNEENLDRDPPAPGRFKFQVVARE-P 475
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE------LSNHNFESVMMIP 1180
DVNDN+PK + +++ + N E +
Sbjct: 476 RTNAASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVV 535
Query: 1181 VYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMV 1240
Y N + K N T G +L Q + LSS AI+ V
Sbjct: 536 TYSIYHVSN----NGIQKFTINATTGEIRTQGRLLAGEQYSITVQATDIGGLSSQAIVEV 591
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEE--NVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
+V P+ + P F YE+++ E +N+ V +V E EN + Y I++ N
Sbjct: 592 SVTPGPN----TKPPRFQKPIYEVQVSEGAEINSTVTVVH---AEDPENDAVVYSIISGN 644
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
D R F + +G + ++R DRE Y++I++AE
Sbjct: 645 DL---RQFAVGQESGVIIVIRKLDRESLTRYQLILKAE 679
Score = 77.0 bits (181), Expect = 4e-12
Identities = 118/524 (22%), Positives = 226/524 (43%), Gaps = 57/524 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK-VKAVDPDLGQNGMVLYDLQR 501
+ + V + D NDN P F+ + YE ++ + VGT I + ++A+D D G NG+V Y +
Sbjct: 126 IPIIVRVSDINDNAPRFM-NTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEYFIAE 184
Query: 502 TS-NLTITSPFKIN---------PNTGTVSVAESPILE--GRHALFVEASDQPANPSERR 549
S N T + + P+ G V+VA++ E + L + ASD+ N ++R
Sbjct: 185 GSPNSTNVEKYSADGYGTFAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTADRL 244
Query: 550 YSLAVVTIEVTRGTKGNKPDI----PDFMGAPYEFWVGSNVGIGTSVGQIRV----NDAF 601
S +T+ + + I GA ++V G+ +G + V A
Sbjct: 245 SSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAV 304
Query: 602 EQNDVSYDLLHGYEEGVP------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
+ + ++ + + + G+P F ++E +GV+ + YD A + +
Sbjct: 305 DLDTINSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEVSPG 364
Query: 656 LSIVTNATVHV-VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
T A + + V D ++ + + +V ENS H N S T
Sbjct: 365 PQRFTTAKLEIFVKPVDANPPVISSSQAE--GYVDENSPIGTRVLDAHGNPISFM---TT 419
Query: 715 NVRFLIANQQD------VTDDIAIAEDG-TIFTQKPLDRE--KRDVYRMTVIAEFNKGVI 765
+ ++ + T + DG + ++ LDR+ ++ V+A +
Sbjct: 420 DADLSDSDPKPDYIYELTTPSFNVTGDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNA 479
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ A + +T+++ D NDN P I + +E ++ + ATD DEG NA+
Sbjct: 480 ASAPL-SLTVHLRDVNDNAPKLAMVAP---ISITAGDQSESRLVTQVTATDNDEGPNAVV 535
Query: 826 MYTLF---GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM 882
Y+++ G + F ++ TG ++ G L E+ Y +++ A D GGLSS+A + +
Sbjct: 536 TYSIYHVSNNGIQKFTINATTGEIRTQGRLLAGEQ---YSITVQATDIGGLSSQAIVEVS 592
Query: 883 IGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK-PKN 925
+ + KP Q + +V++ ++N T T++ + P+N
Sbjct: 593 VTPGPNTKPPRFQ-KPIYEVQVSEGAEINSTV--TVVHAEDPEN 633
Score = 68.9 bits (161), Expect = 1e-09
Identities = 115/489 (23%), Positives = 193/489 (39%), Gaps = 58/489 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L S V + + D ND NP F S L Y F ++ K +G V A D D G N + Y
Sbjct: 684 LSSSATVNIKVTDINDKNPEFEASTLPYVFQVE-EGKAQASVGVVHATDADEGINAEITY 742
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVV 555
++ PF IN +G + A+ E + V A D + R A V
Sbjct: 743 ------SIPTDIPFTINATSGEILTAKELDYEQLNEYKFVVTAKD---GAPDARLGTASV 793
Query: 556 TIEVTRGTKGNKPD-IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
T+ V + PD +P F A + + N V ++ D +++Y L G
Sbjct: 794 TVMVL-----DLPDEVPKFSDARIDVHIPENEE-NFLVATVQAFDPDSMPEITYVLRKGN 847
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
E F V E+SG + + L ++ + ++ + N + + VVDV D
Sbjct: 848 AE--LFKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGP--GDTILLVVDVEDRND 903
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT--GN-VRFLIANQQDVTDDIA 731
+ + P V ++ IG I T + +I G+GT GN VR+ I +
Sbjct: 904 LPPRFITVPDPVTVNDDQ---GIGTIIAT-LPAIDGDGTSPGNVVRYEIVGRGKAPKYFQ 959
Query: 732 IAED-GTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIY-------IEDEND 782
+ D G + + L +E+ Y++ + A + + +S +V ++ E + D
Sbjct: 960 VDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLD 1019
Query: 783 NP-------------PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
N F +Y + E+ + + +K+ I+ + + +G A +
Sbjct: 1020 NKLESGTGMSSESIGLAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFV 1079
Query: 830 FGEGKEMFDVDE-NTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIG 884
G G +F++ + G + LD E K Y L L L + I++
Sbjct: 1080 SGNGGGIFNLSSADHGCNLLLIQPLDFENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQ 1139
Query: 885 DENDNKPEF 893
DENDN PEF
Sbjct: 1140 DENDNAPEF 1148
Score = 62.9 bits (146), Expect = 7e-08
Identities = 139/617 (22%), Positives = 233/617 (37%), Gaps = 84/617 (13%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVG---QIRVNDAFEQNDVSYDLLHGYEEGV--------- 618
P FM PYE V + +GT++ Q DA V Y + G
Sbjct: 140 PRFMNTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADG 199
Query: 619 --PFAVE-ERSGVITVVDDLSRYNRPMYDFEAVALQENAN----LSIVTNATVHVVDVND 671
FA+ G +TV L Y VA N LS T TV++ D ND
Sbjct: 200 YGTFAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADSND 259
Query: 672 -ERGVLLKGAHS--PIIFHVKENS---AGAAIG--QIFHTNMSSIYGNGTGN-VRFLIAN 722
+ + G S + + ++ AG+ +G + + ++ + + +R+ A+
Sbjct: 260 LDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAVDLDTINSPIRYSFAS 319
Query: 723 QQ--DVTDDIAIAEDGTIFTQ-KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ D I E + Q K +D Y + V AE ++ I+++
Sbjct: 320 GMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEVSPGPQRFTTAKLEIFVKP 379
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
+ NPPV + EG++ ENS IGT + DA G FM T D
Sbjct: 380 VDANPPVISSSQAEGYVDENSPIGTRV--------LDA-HGNPISFMTT---------DA 421
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNK--PEFNQIE 897
D + DS D + +Y+L+ T + + I+++ +EN ++ P + +
Sbjct: 422 D--------LSDS-DPKPDYIYELT-----TPSFNVTGDGILVVNEENLDRDPPAPGRFK 467
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALD 957
R R + T+ ++ N A + + P+ + + + ++ A D
Sbjct: 468 FQVVAREPRTNAASAPLSLTV-HLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATD 526
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI 1017
D G N + Y +Y +S + ++ F IN G + L ++ + +
Sbjct: 527 NDEGPNAVVTYS----IY----HVSNNGIQK---FTINATTGEIRTQGRLLAGEQYSITV 575
Query: 1018 SALDGGNLNDNISVRVFVKD-VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
A D G L+ V V V N P F+K Y V E + V A D +
Sbjct: 576 QATDIGGLSSQAIVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPE--- 632
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
N + Y I + F + +GV+ V +LDRE+ +Y L + A D G
Sbjct: 633 NDAVVYSIISGNDLRQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTG---GLSSSAT 689
Query: 1137 XXXXXXDVNDNSPKFYA 1153
D+ND +P+F A
Sbjct: 690 VNIKVTDINDKNPEFEA 706
Score = 59.3 bits (137), Expect = 8e-07
Identities = 83/331 (25%), Positives = 142/331 (42%), Gaps = 30/331 (9%)
Query: 75 NQISAYLSVTVYIEDVNDNVP-IFLDTPYHVTVDELTPTGEKAFIFLIA-PIGPSLTIPL 132
N SA LS+TV++ DVNDN P + + P +T + + + + GP+ +
Sbjct: 478 NAASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTY 537
Query: 133 TV----PRGLTIFKDIRAFDRDKPNTPN--SDVHYSI-VSGNDDGHFALESSHKPVLLLR 185
++ G+ F I A + + YSI V D G + ++ + +
Sbjct: 538 SIYHVSNNGIQKFT-INATTGEIRTQGRLLAGEQYSITVQATDIGGLSSQAIVEVSVTPG 596
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
K V ++ G I+ + +HA D + + Y +ISGND + F+
Sbjct: 597 PNTKPPRFQKPIYEVQVSEGAEINSTVTV---VHAEDPE---NDAVVYSIISGNDLRQFA 650
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
+ +G + + ++LD ++ + L ++A ++ A V I++ D+ND PE
Sbjct: 651 VGQESGVIIVIRKLDRES-----LTRYQLILKAEDTGG--LSSSATVNIKVTDINDKNPE 703
Query: 306 FEVDF--YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
FE Y + E SV V ATD D+G N E TY + F+I+ SG +
Sbjct: 704 FEASTLPYVFQVEEGKAQA-SVGVVHATDADEGINAEITYSIPTDI-PFTINATSGEILT 761
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSV-VGT 393
+ LD E + + V AK+ P +GT
Sbjct: 762 AKE--LDYEQLNEYKFVVTAKDGAPDARLGT 790
Score = 56.8 bits (131), Expect = 4e-06
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 12/152 (7%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
R E +SGN +F+L S + L LD E+ + + NPLK +
Sbjct: 1075 RCEFVSGNGGGIFNLSSADHGCNLLLIQPLDFENKSSYSLQLRLTSHRYFVNPLKDTTS- 1133
Query: 292 VEIELLDLNDNLPEFEVD--------FYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
VEI + D NDN PEFE + FY + + E + ++LQV ATD+D G+ G Y
Sbjct: 1134 VEIIVQDENDNAPEFEFNRLRGQQDTFYTV-VTEEMDVDTTILQVRATDRDSGKFGTVRY 1192
Query: 344 QL-DDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
L DD + ++ P S ++ + VL H
Sbjct: 1193 TLYDDDENRVNM-PTSFFMMSEDTGVLRTAKH 1223
Score = 51.6 bits (118), Expect = 2e-04
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 14/165 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D G+ A + Y + + F++++ +G + KELD + Q N + V
Sbjct: 727 VHATDADEGINAEITYSIPTDIP---FTINATSGEILTAKELDYE-----QLNEYKFVVT 778
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + A V + +LDL D +P+F ++ I EN N F V V A D D
Sbjct: 779 AKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEEN-FLVATVQAFDPD--S 835
Query: 338 NGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
E TY L F + +SG VR LD E+ ++ +
Sbjct: 836 MPEITYVLRKGNAELFKVSEKSG--EVRTIKGLDYESQKQHQLTI 878
Score = 47.2 bits (107), Expect = 0.003
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 26/219 (11%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+ T + ++ KN + L +F + E ++ ++A D D G+N +I Y
Sbjct: 687 SATVNIKVTDINDKNP-EFEASTLPYVFQVEEG-KAQASVGVVHATDADEGINAEITYSI 744
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLN 1026
++ IP F IN G ++ A+ L E +E++ ++A DG
Sbjct: 745 PTD--IP--------------FTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARL 788
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
SV V V D+ D P F + ++ E + ++ V A D D +TY ++
Sbjct: 789 GTASVTVMVLDLPDEVPKFSDARIDVHIPENE-ENFLVATVQAFDPD--SMPEITYVLRK 845
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ +L F++S +G + LD E++ ++ LT+ +N
Sbjct: 846 GNAEL-FKVSEKSGEVRTIKGLDYESQKQHQLTIGTIEN 883
Score = 46.4 bits (105), Expect = 0.006
Identities = 109/474 (22%), Positives = 185/474 (39%), Gaps = 67/474 (14%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V V +LD D P F + + + + N + ++ V+A DPD + Y L R
Sbjct: 792 SVTVMVLDLPDEVPKFSDARI-DVHIPENEE-NFLVATVQAFDPDSMPE--ITYVL-RKG 846
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPAN-PSERRYSLAVVTIEVT 560
N + FK++ +G V + E + H L + + N P + L VV +E
Sbjct: 847 NAEL---FKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGPGDT--ILLVVDVE-- 899
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEEG 617
+ + P P F+ P V + GIGT + + D N V Y+++ +
Sbjct: 900 --DRNDLP--PRFITVPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNVVRYEIVGRGKAP 955
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMY--DFEAVALQENANLSIVTNATVHV--------- 666
F V+ +G + + D+L + Y D A L E LS V V V
Sbjct: 956 KYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGE-PQLSSVAPLRVDVHHLLSSGNN 1014
Query: 667 ---VDVNDERGVLLKGAHSPIIFH-------VKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+D E G + + F V E+ + ++ S G+G
Sbjct: 1015 EIKLDNKLESGTGMSSESIGLAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAF 1074
Query: 717 R--FLIANQQDVTDDIAIAEDG-TIFTQKPLDREKRDVYRMTVIAEFNKGVISGA-GIYQ 772
R F+ N + + ++ A+ G + +PLD E + Y + + ++ ++
Sbjct: 1075 RCEFVSGNGGGIFN-LSSADHGCNLLLIQPLDFENKSSYSLQLRLTSHRYFVNPLKDTTS 1133
Query: 773 VTIYIEDENDNPPVFE-------HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
V I ++DENDN P FE T+ + E + T I ++ATD D G
Sbjct: 1134 VEIIVQDENDNAPEFEFNRLRGQQDTFYTVVTEEMDVDTTILQ---VRATDRDSGKFGTV 1190
Query: 826 MYTLFGEGK-------EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
YTL+ + + F + E+TGV++ E + ARD+ G
Sbjct: 1191 RYTLYDDDENRVNMPTSFFMMSEDTGVLR-TAKHFKNENDFPLTFLVEARDSDG 1243
Score = 46.0 bits (104), Expect = 0.008
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 15/126 (11%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTI 140
+ + V + D+NDN P F++TPY VTV E TP G F + A + + GL
Sbjct: 126 IPIIVRVSDINDNAPRFMNTPYEVTVPESTPVGTTIFRNIQA-LDKDAGV-----NGLVE 179
Query: 141 FKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLV 200
+ PN+ N + + S + G FA+ H+ + + K LD++ + + L
Sbjct: 180 Y----FIAEGSPNSTNVEKY----SADGYGTFAISFPHQGQVTVAKTLDFEK-IQTYYLT 230
Query: 201 IMASGK 206
I+AS +
Sbjct: 231 IVASDR 236
Score = 44.8 bits (101), Expect = 0.018
Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISAL--DGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F ++E+ G V + L ES+ +L I + DG D I + V V+D ND P F
Sbjct: 851 FKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFIT 910
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVN 1105
V + Q ++ + A D D N+ + P F++ P TG + +
Sbjct: 911 VPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVRIR 970
Query: 1106 GELDRETEDKYILTVVARDNG 1126
EL +E + +Y + + A D G
Sbjct: 971 DELRKEEDTEYQVDIRAYDLG 991
Score = 41.1 bits (92), Expect = 0.23
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
L H+++ V+ K + ++VR+ D+NDN+P+F N P +P + P G + +
Sbjct: 106 LSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFM--NTPYEVTVPESTPVGTTIFR 163
Score = 39.1 bits (87), Expect = 0.92
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 15/115 (13%)
Query: 1025 LNDNISVRVFVKDVNDHFPVF--------KKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
L D SV + V+D ND+ P F + T+Y EE +L +V ATD D G+
Sbjct: 1128 LKDTTSVEIIVQDENDNAPEFEFNRLRGQQDTFYTVVTEEMDVDTTIL-QVRATDRDSGK 1186
Query: 1077 NANLTYFIQPSD---TDLP---FEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
+ Y + D ++P F +S TGVL E + V ARD+
Sbjct: 1187 FGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAKHFKNENDFPLTFLVEARDS 1241
Score = 36.3 bits (80), Expect = 6.5
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 9/100 (9%)
Query: 434 YYDEQLMSFVNVEVTLLDANDNNPVFVPSNL------YEFSMKSNAKVGTVIGKVKAVDP 487
Y+ L +VE+ + D NDN P F + L + + V T I +V+A D
Sbjct: 1123 YFVNPLKDTTSVEIIVQDENDNAPEFEFNRLRGQQDTFYTVVTEEMDVDTTILQVRATDR 1182
Query: 488 DLGQNGMVLYDLQRTSNLTITSP---FKINPNTGTVSVAE 524
D G+ G V Y L + P F ++ +TG + A+
Sbjct: 1183 DSGKFGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAK 1222
>UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1139
Score = 119 bits (286), Expect = 7e-25
Identities = 175/781 (22%), Positives = 325/781 (41%), Gaps = 57/781 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G AY + + +N+ +P+ +TP+ ++V + G F ++I SL +
Sbjct: 404 GAMNYEAYFTNDFFNTTINELMPV--NTPF-LSVAPRSAVGNTGFSYVITD--SSLPFSI 458
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
G+ AFD D+ TP + +++ N ++ + V++L D +
Sbjct: 459 GTHTGMLSV----AFDLDRETTP--EYEFTVAVRNAKQQTIADT--RVVVILSDANDNNP 510
Query: 193 G-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
++E V + + H ++L + A D DLG + Y + + N F++D G
Sbjct: 511 SFEEEIYTVEVEENRPAHSQVLV---VRASDPDLGENGFISYSIANLNAVP-FTIDHETG 566
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT-AQARVEIELLDLNDNLPEFEVDF 310
S+ K LD + + + L+V+AS +P + A+A V + L++LNDN P+FE
Sbjct: 567 SINTSKVLDYET----MRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFEKIN 622
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
+I ++ P+G ++ + A D D+ + + FSI+P+SG LT+
Sbjct: 623 CVGAIAKSFPSGRAIALISALDFDE-NRPRYWITSGNVNDLFSINPQSGNLTLSRPVADS 681
Query: 371 REAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTE 430
SLR++ T+ S + T A Q + +++
Sbjct: 682 DPLFYSLRIEARDGPTSVSYMRTNMTITNNANPSPQAHARGLKVTCQETDVAEEIEELYG 741
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
+E ++++ L +N + P F + +A VG + V A D D G
Sbjct: 742 QLEASNQEVEHLPPNYAELYSSNVHEPEFETGFRTSVEVPEDAPVGGTVLTVNANDLDHG 801
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSE 547
NG +LY + S+ S F+++ TG + V P+ + + + V+ SD P
Sbjct: 802 FNGKLLYAI---SDGNDKSHFQMDFETGELKVL-MPLDRETQSTYDVTVKISDM-GKPQH 856
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
R S +T+ T N + P F Y+ + + +G S + +D E +
Sbjct: 857 TRKSPLTITL-----TDVN-DNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQE 910
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATV 664
V Y ++ + F ++ +G ++V L R P+++ A ++ LS V
Sbjct: 911 VRYSII---SDSPSFDIDIITGELSVAGPLDRETNPVHEIRVQATDLSDSPLSSSVIVRV 967
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
+ D+ND L + I ++ GAA+ + + NGT R +
Sbjct: 968 SLDDINDNPPRCLLPEYKVKI--REDLPTGAAVLSV-QAHDPDNPPNGTVRYRLDTSGSS 1024
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN- 783
+ D + GT+ + LD E +Y + V+A ++G+ + + ++ + + D N+N
Sbjct: 1025 KFSID---TDYGTLRLVEMLDYEVTQLYEI-VVAIRDEGIPAMSSTCRIVVEVVDVNENT 1080
Query: 784 -PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDE 841
PVF + G + E TE+ I A D D G + YT+ G G F +D
Sbjct: 1081 HAPVFPNYVLTGSVHEGHINDTEVM---TISAADMDMGIDGEVSYTIRDGSGLGRFSIDS 1137
Query: 842 N 842
+
Sbjct: 1138 S 1138
Score = 106 bits (254), Expect = 5e-21
Identities = 193/823 (23%), Positives = 314/823 (38%), Gaps = 79/823 (9%)
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMV--LYDLQRTSNLTITSPFKINPNTGTVSVAES 525
++ N+++GTV V D D G NG + L + +P + +A S
Sbjct: 309 TVSRNSEIGTVFAVVGVTDEDGGVNGEIAALDIIDGDPGGFFRVQPSPSPGRYQLQIARS 368
Query: 526 PILEGR-HA--LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
+ HA + V ASD+ +P S ++V V G + F + +
Sbjct: 369 LLSSSLPHAFNVTVAASDRGLSPK----STSLVVGVVLDGAMNYEAY---FTNDFFNTTI 421
Query: 583 GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
+ + T + A SY + + +PF++ +G+++V DL R P
Sbjct: 422 NELMPVNTPFLSVAPRSAVGNTGFSYVIT---DSSLPFSIGTHTGMLSVAFDLDRETTPE 478
Query: 643 YDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
Y+F T V + D ND + ++ V+EN A Q+
Sbjct: 479 YEFTVAVRNAKQQTIADTRVVVILSDANDNNPSFEEEIYT---VEVEENRP--AHSQVLV 533
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK-RDVYRMTVIAEFN 761
S G + + IAN V I E G+I T K LD E R YR+ V A
Sbjct: 534 VRASDPDLGENGFISYSIANLNAVPFTID-HETGSINTSKVLDYETMRHQYRLRVRASDW 592
Query: 762 KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT 821
V + + + NDN P FE G I ++ G I + I A D DE
Sbjct: 593 GSPFRREAKAVVIVNLINLNDNRPKFEKINCVGAIAKSFPSGRAIAL---ISALDFDENR 649
Query: 822 NALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
++ + G ++F ++ +G + D + + Y L + ARD S +
Sbjct: 650 PRYWITS--GNVNDLFSINPQSGNLTLSRPVADSDP-LFYSLRIEARDGPTSVSYMRTNM 706
Query: 882 MIGDENDNKPEFNQ------IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLG 935
I + + P+ + +E E A +E P N L +
Sbjct: 707 TITNNANPSPQAHARGLKVTCQETDVAEEIEELYGQLEASNQEVEHLPPNYAELYSSNVH 766
Query: 936 -PLFL--------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
P F +PE+ P+G T++ +NA DLD G NG++ Y + D
Sbjct: 767 EPEFETGFRTSVEVPEDAPVGGTVLTVNANDLDHGFNGKLLYAISD---------GNDKS 817
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
+ F E + + R + + IS + + + + DVND+ P F
Sbjct: 818 HFQMDFETGELKVLMPLDRETQSTYDVTVKISDMGKPQHTRKSPLTITLTDVNDNAPQFD 877
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
Y+ + E V A+D D G+N + Y I SD+ F+I +TG LSV G
Sbjct: 878 LKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSII-SDSP-SFDIDIITGELSVAG 935
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
LDRET + + V A D D+NDN P+ L E+K +
Sbjct: 936 PLDRETNPVHEIRVQATDL-SDSPLSSSVIVRVSLDDINDNPPRCL----LPEYKVKIRE 990
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPI----GTTVAKVFANDTDFIGNGNGLILYSLPQRK 1222
+L +V+ + + N + T+ + F+ DTD+ G ++ L
Sbjct: 991 DLPTG--AAVLSVQAHDPDNPPNGTVRYRLDTSGSSKFSIDTDY---GTLRLVEMLDYEV 1045
Query: 1223 NQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
Q ++ G+P++SST ++V V DV E + PVF
Sbjct: 1046 TQLYEIVVAIRDEGIPAMSSTCRIVVEVVDVN---ENTHAPVF 1085
Score = 74.1 bits (174), Expect = 3e-11
Identities = 113/476 (23%), Positives = 192/476 (40%), Gaps = 50/476 (10%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + + D N+ P+F+ N Y ++ + V + I +V+A D D G NG V Y +
Sbjct: 176 STAEVHIVVQDVNEQPPLFLRGN-YAATISEDYPVFSNIIQVEAHDSDSGTNGEVYYSFR 234
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ T F I+ TG VS+ P+ + + L V A D+ P + V +
Sbjct: 235 QQ-----TDQFAIHTTTGVVSLTR-PLDFDQQSSYTLTVVAKDRGFTPYGGLPLTSPVQL 288
Query: 558 EV-TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHG 613
+ + + P+I + V N IGT + V D + D++ G
Sbjct: 289 RIYVQQVNKHSPEI----RIEKQPTVSRNSEIGTVFAVVGVTDEDGGVNGEIAALDIIDG 344
Query: 614 YEEGVPFAVEERSG----VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
+ G F V+ + + L + P + F + LS +T VV
Sbjct: 345 -DPGGFFRVQPSPSPGRYQLQIARSLLSSSLP-HAFNVTVAASDRGLS--PKSTSLVV-- 398
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN---MSSIYGNGTGNVRF-LIANQQD 725
GV+L GA + + + I ++ N +S + GN F +
Sbjct: 399 ----GVVLDGAMNYEAYFTND-FFNTTINELMPVNTPFLSVAPRSAVGNTGFSYVITDSS 453
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ I G + LDRE Y TV + + I+ +V + + D NDN
Sbjct: 454 LPFSIG-THTGMLSVAFDLDRETTPEYEFTVAVRNAKQQTIADT---RVVVILSDANDNN 509
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P FE Y + EN +++ +++A+D D G N Y++ F +D TG
Sbjct: 510 PSFEEEIYTVEVEENRPAHSQVL---VVRASDPDLGENGFISYSIANLNAVPFTIDHETG 566
Query: 845 VVKFIGDSLDRE-KKIMYKLSLVARDTGG-LSSEAELIIMIG--DENDNKPEFNQI 896
+ LD E + Y+L + A D G EA+ ++++ + NDN+P+F +I
Sbjct: 567 SIN-TSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFEKI 621
Score = 71.3 bits (167), Expect = 2e-10
Identities = 51/171 (29%), Positives = 86/171 (50%), Gaps = 13/171 (7%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
++RE R Y +T IA+ + G + +V I ++D N+ PP+F Y I E+ +
Sbjct: 151 VNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVF 210
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+ I ++A D+D GTN Y+ F + + F + TGVV + LD +++ Y L
Sbjct: 211 SNIIQ---VEAHDSDSGTNGEVYYS-FRQQTDQFAIHTTTGVVS-LTRPLDFDQQSSYTL 265
Query: 864 SLVARDTG-------GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
++VA+D G L+S +L I + N + PE +IE+ V + E
Sbjct: 266 TVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEI-RIEKQPTVSRNSE 315
Score = 58.8 bits (136), Expect = 1e-06
Identities = 87/311 (27%), Positives = 133/311 (42%), Gaps = 37/311 (11%)
Query: 1039 NDHFPVFKKTWYNFNVE---EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
N H P F+ T + +VE +A VL V+A D D G N L Y I + F++
Sbjct: 764 NVHEPEFE-TGFRTSVEVPEDAPVGGTVL-TVNANDLDHGFNGKLLYAISDGNDKSHFQM 821
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
TG L V LDRET+ Y +TV D G DVNDN+P+F
Sbjct: 822 DFETGELKVLMPLDRETQSTYDVTVKISDMGKPQHTRKSPLTITLT-DVNDNAPQFDL-- 878
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEE--NAPIGTTVAKVFAN-DTDFIGNGNG 1212
+ + PE E+ + + V+ + +E N + ++ + D D I G
Sbjct: 879 KQYDVAIPEDAEVG------LSFLAVHASDRDEGRNQEVRYSIISDSPSFDIDII-TGEL 931
Query: 1213 LILYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
+ L + N +L LSS+ I+ V++ D+ D + P + Y++
Sbjct: 932 SVAGPLDRETNPVHEIRVQATDLSDSPLSSSVIVRVSLDDIND-----NPPRCLLPEYKV 986
Query: 1265 EIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+I E++ A V V + ++ N +RY + DT F ID GTL LV D
Sbjct: 987 KIREDLPTGAAVLSVQAHDPDNPPNGTVRYRL----DTSGSSKFSIDTDYGTLRLVEMLD 1042
Query: 1323 REVKDTYEVIV 1333
EV YE++V
Sbjct: 1043 YEVTQLYEIVV 1053
Score = 57.6 bits (133), Expect = 2e-06
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 1003 VARSLPPESEFRLNISALDGG-NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
V R + PE + GG V + V+DVN+ P+F + Y + E
Sbjct: 151 VNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVF 210
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ +V+A D+D G N + Y + TD F I TGV+S+ LD + + Y LTVV
Sbjct: 211 SNIIQVEAHDSDSGTNGEVYYSFR-QQTD-QFAIHTTTGVVSLTRPLDFDQQSSYTLTVV 268
Query: 1122 ARDNG 1126
A+D G
Sbjct: 269 AKDRG 273
Score = 53.6 bits (123), Expect = 4e-05
Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 9/203 (4%)
Query: 260 DLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL 319
+L ++ ++ + S T+ A V I + D+N+ P F Y +I E+
Sbjct: 148 NLKVNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDY 207
Query: 320 PNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
P +++QV A D D G NGE Y F+I +G +++ LD + SS +
Sbjct: 208 PVFSNIIQVEAHDSDSGTNGEVYYSFRQQTDQFAIHTTTGVVSLTRP--LDFDQQSSYTL 265
Query: 380 KVYAKETNPSVVGTFADSQRI-AKWRRQPLETNAP---LEKTTYVFPD-KVGTKTENIEY 434
V AK+ + G + + + Q + ++P +EK V + ++GT +
Sbjct: 266 TVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEIRIEKQPTVSRNSEIGTVFAVVGV 325
Query: 435 YDEQLMSFVNVEVTLLDANDNNP 457
DE VN E+ LD D +P
Sbjct: 326 TDED--GGVNGEIAALDIIDGDP 346
Score = 52.8 bits (121), Expect = 7e-05
Identities = 52/196 (26%), Positives = 91/196 (46%), Gaps = 21/196 (10%)
Query: 635 LSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENS 692
++R RP Y A+A + + + A VH+V DVN++ + L+G ++ I ++
Sbjct: 151 VNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATIS--EDYP 208
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDV 751
+ I Q+ + S GT + QQ TD AI G + +PLD +++
Sbjct: 209 VFSNIIQVEAHDSDS----GTNGEVYYSFRQQ--TDQFAIHTTTGVVSLTRPLDFDQQSS 262
Query: 752 YRMTVIAEFNKGVISGAGI-----YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
Y +TV+A+ ++G G+ Q+ IY++ N + P + + NS+IGT
Sbjct: 263 YTLTVVAK-DRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEI-RIEKQPTVSRNSEIGTVF 320
Query: 807 KMDNIIKATDADEGTN 822
++ TD D G N
Sbjct: 321 A---VVGVTDEDGGVN 333
Score = 47.2 bits (107), Expect = 0.003
Identities = 98/451 (21%), Positives = 180/451 (39%), Gaps = 75/451 (16%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P + ++ + A D D G NG I Y + +P F I+ G
Sbjct: 521 VEENRPAHSQVLVVRASDPDLGENGFISYSIANLNAVP--------------FTIDHETG 566
Query: 1000 HVIVARSLPPES---EFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ ++ L E+ ++RL + A D G+ V V + ++ND+ P F+K
Sbjct: 567 SINTSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFEKINCVGA 626
Query: 1054 VEEAQYTRRVLGKVDATDADFGQ--------NANLTYFIQPSDTDLPF-----EISPLTG 1100
+ ++ + R + + A D D + N N + I P +L + PL
Sbjct: 627 IAKSFPSGRAIALISALDFDENRPRYWITSGNVNDLFSINPQSGNLTLSRPVADSDPLFY 686
Query: 1101 VLSVNGELDRETEDKYI---LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY----A 1153
L + D T Y+ +T+ N DV + + Y A
Sbjct: 687 SLRIEAR-DGPTSVSYMRTNMTITNNANPSPQAHARGLKVTCQETDVAEEIEELYGQLEA 745
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIE--ENAPIGTTVAKVFANDTDF----- 1206
++ +E P EL + N ++ ++E E+AP+G TV V AND D
Sbjct: 746 SNQEVEHLPPNYAELYSSNVHEPEFETGFRTSVEVPEDAPVGGTVLTVNANDLDHGFNGK 805
Query: 1207 ----IGNGNGLILYSLPQRKNQQNLGLP---SLSSTAILMVTVADV---------PDEVE 1250
I +GN + + + + +P ST + V ++D+ P +
Sbjct: 806 LLYAISDGNDKSHFQMDFETGELKVLMPLDRETQSTYDVTVKISDMGKPQHTRKSPLTIT 865
Query: 1251 MSD----KPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRR 1304
++D P F + Y++ I E+ + ++++ ++ E N ++RY I++++
Sbjct: 866 LTDVNDNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSIISDSP----- 920
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+F ID G L + DRE +E+ V+A
Sbjct: 921 SFDIDIITGELSVAGPLDRETNPVHEIRVQA 951
Score = 46.0 bits (104), Expect = 0.008
Identities = 110/494 (22%), Positives = 184/494 (37%), Gaps = 70/494 (14%)
Query: 930 DVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DV++ PLFL I E+ P+ + II++ A D DSG NG++ Y F + +
Sbjct: 186 DVNEQPPLFLRGNYAATISEDYPVFSNIIQVEAHDSDSGTNGEVYYSFRQQTDQFAIHTT 245
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHF 1042
+ + R +++ + + + + F + G L + +R++V+ VN H
Sbjct: 246 TGVVSLTRPLDFDQQSSYTLTV--VAKDRGF----TPYGGLPLTSPVQLRIYVQQVNKHS 299
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF-IQPSDTDLPFEI--SPLT 1099
P + V V V TD D G N + I D F + SP
Sbjct: 300 PEI-RIEKQPTVSRNSEIGTVFAVVGVTDEDGGVNGEIAALDIIDGDPGGFFRVQPSPSP 358
Query: 1100 G---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
G + L + +TV A D G V D + + A+
Sbjct: 359 GRYQLQIARSLLSSSLPHAFNVTVAASDRGLSPKSTSLVVGV-----VLDGAMNYEAY-- 411
Query: 1157 LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF---IGNGNGL 1213
++ N +M + ++ + +G T D+ IG G+
Sbjct: 412 -------FTNDFFNTTINELMPVNTPFLSVAPRSAVGNTGFSYVITDSSLPFSIGTHTGM 464
Query: 1214 ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD----KPVFISRYYELEIEEN 1269
+ + + +++ T+AD V +SD P F Y +E+EEN
Sbjct: 465 LSVAFDLDRETTPEYEFTVAVRNAKQQTIADTRVVVILSDANDNNPSFEEEIYTVEVEEN 524
Query: 1270 --VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE-VK 1326
++ V +V + + EN + Y I N N F ID G++ + D E ++
Sbjct: 525 RPAHSQVLVVRASDPDLGENGFISYSIANLNAV----PFTIDHETGSINTSKVLDYETMR 580
Query: 1327 DTYEVIVRAE--RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
Y + VRA + RE A+ V V+V + ++NDN PKF N
Sbjct: 581 HQYRLRVRASDWGSPFRRE--------AKAV----------VIVNLINLNDNRPKFEKIN 622
Query: 1385 RPLVTAIPTTAPFG 1398
V AI + P G
Sbjct: 623 --CVGAIAKSFPSG 634
>UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome shotgun
sequence; n=6; Clupeocephala|Rep: Chromosome 9 SCAF14710,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 4006
Score = 119 bits (286), Expect = 7e-25
Identities = 129/479 (26%), Positives = 200/479 (41%), Gaps = 31/479 (6%)
Query: 455 NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKIN 514
N F P Y+ + N GT + + A DPD G G V Y + N + F I+
Sbjct: 923 NRHPFFPQYNYQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSMAPLMNSRSSDYFHIH 982
Query: 515 PNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
P TG ++ ++ E H V A+D S R +V I V+ P
Sbjct: 983 PETGLITTTQTLDREHMDLHYFRVTATDY---GSSRLSGTTMVAITVS----DRNDHSPI 1035
Query: 573 FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGY--EEGVPFAVEERSGV 628
F Y + NV G + Q+R D+ ++ Y + F ++ RSG+
Sbjct: 1036 FEQTEYRETIRENVEEGYPILQLRATDSDSPTNANIRYRFIGDMVAVARAAFEIDPRSGL 1095
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGAHSPIIFH 687
IT + R Y + A + +ATV V + V DE + + + +
Sbjct: 1096 ITTRGVVDRELNEHYTLQVEASDQGKEPG-PRSATVKVFITVLDENDNVPQFSEKRYVVA 1154
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
VKEN + +I + + + V + I + + G I PLD E
Sbjct: 1155 VKENVRPHS--EILRVSATDRDKDSNAAVHYNIISGNSRGQFSIDSVTGEIQVVAPLDYE 1212
Query: 748 KRDVYRMTVIAEFN--KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
Y + V A+ N + + GI V++ + D NDNPP+F ++ ++E+S +G+
Sbjct: 1213 AEREYTLRVRAQDNGRPPLSNNTGI--VSVQVTDVNDNPPIFVSTPFQASVLESSPVGSS 1270
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLS 864
I I+A D D G NA Y L G + F ++ TG V + +LDRE Y
Sbjct: 1271 ILH---IQAIDTDSGDNARLEYKLTGTSSDTPFIINSATGWVT-VRSTLDRESVEHYFFG 1326
Query: 865 LVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
+ ARD G LS+ A + I + D NDN PEF Q E +++ E GT+ T+ V
Sbjct: 1327 VEARDYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARL---NEDAAVGTSVVTVTAV 1382
Score = 106 bits (255), Expect = 4e-21
Identities = 112/470 (23%), Positives = 193/470 (41%), Gaps = 29/470 (6%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y +L V +T+ D ND++P+F + Y +++ N + G I +++A D D N
Sbjct: 1010 DYGSSRLSGTTMVAITVSDRNDHSPIFEQTE-YRETIRENVEEGYPILQLRATDSDSPTN 1068
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASDQPANPSERRY 550
+ Y + F+I+P +G ++ L + L VEASDQ P R
Sbjct: 1069 ANIRYRFIGDMVAVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPRS- 1127
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSY 608
T++V ++P F Y V NV + + ++ D + ++ V Y
Sbjct: 1128 ----ATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHY 1183
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN---ATVH 665
+++ G G F+++ +G I VV L Y V Q+N + N +V
Sbjct: 1184 NIISGNSRG-QFSIDSVTGEIQVVAPLDYEAEREYTLR-VRAQDNGRPPLSNNTGIVSVQ 1241
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V DVND + + +P V E+S + I H + + +
Sbjct: 1242 VTDVNDNPPIFVS---TPFQASVLESSPVGS--SILHIQAIDTDSGDNARLEYKLTGTSS 1296
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
T I + G + + LDRE + Y V A + G + VTI + D NDN P
Sbjct: 1297 DTPFIINSATGWVTVRSTLDRESVEHYFFGVEAR-DYGTPPLSATASVTITVMDVNDNHP 1355
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
F Y + E++ +GT +++ T D N+ Y + G + F + G
Sbjct: 1356 EFLQKEYYARLNEDAAVGT-----SVVTVTAVDRDVNSAVTYQITGGNTRNRFAISTAGG 1410
Query: 845 V-VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+ + LD +++ Y L++ A D L ++ I I D N ++P F
Sbjct: 1411 AGLLSLALPLDYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVF 1459
Score = 104 bits (250), Expect = 2e-20
Identities = 107/412 (25%), Positives = 176/412 (42%), Gaps = 33/412 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN P+FV S ++ S+ ++ VG+ I ++A+D D G N + Y L TS+
Sbjct: 1238 VSVQVTDVNDNPPIFV-STPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSS 1296
Query: 505 LTITSPFKINPNTGTVSVAESPILEG-RHALF-VEASDQPANPSERRYSLAVVTIEVTRG 562
T PF IN TG V+V + E H F VEA D P S+ + ++V
Sbjct: 1297 DT---PFIINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDV--- 1350
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P+F+ Y + + +GTSV + D + V+Y + G FA+
Sbjct: 1351 ----NDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGNTRN-RFAI 1405
Query: 623 EER--SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+G++++ L Y A + L +++ D N R V + A
Sbjct: 1406 STAGGAGLLSLALPLDYKQERRYVLTVTA--SDRTLHDTCQVHINITDANTHRPV-FQSA 1462
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIAEDGTIF 739
H + V E+S ++ M S + G N R + ++ + G I
Sbjct: 1463 HYSV--SVNEDSPPGSL-----VVMISATDDDVGENARITYLLEDNIPQFRIDSATGAIT 1515
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
Q LD E + Y + + A+ N G+ + V + + D NDN P F Y+G + E+
Sbjct: 1516 LQAELDYEDQMTYTLAITAKDN-GIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSED 1574
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVKFI 849
+ T + I ATD D N YT +G F ++ +G+++ I
Sbjct: 1575 APPFTSVLQ---ISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGILRTI 1623
Score = 103 bits (247), Expect = 4e-20
Identities = 101/411 (24%), Positives = 186/411 (45%), Gaps = 69/411 (16%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ +GT+++ + A+D D +N + Y+ + F I+ G
Sbjct: 1368 EDAAVGTSVVTVTAVDRD--VNSAVTYQITGG-------------NTRNRFAISTAGGAG 1412
Query: 1002 IVARSLP----PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+++ +LP E + L ++A D L+D V + + D N H PVF+ Y+ +V E
Sbjct: 1413 LLSLALPLDYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVFQSAHYSVSVNED 1471
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
++ + ATD D G+NA +TY ++ D F I TG +++ ELD E + Y
Sbjct: 1472 SPPGSLVVMISATDDDVGENARITYLLE--DNIPQFRIDSATGAITLQAELDYEDQMTYT 1529
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L + A+DNG DVNDN+P+F
Sbjct: 1530 LAITAKDNG-IPQKSDTTYVEVNVNDVNDNAPQF-------------------------- 1562
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAI 1237
+ P Y+ ++ E+AP T+V ++ A D D + NG + Y+ + + G ++ T+
Sbjct: 1563 LSPRYQGSVSEDAPPFTSVLQISATDRD--AHANGRVQYTF--QNGEDGDGDFTIEPTSG 1618
Query: 1238 LMVTVADVPDE----------VEMSDK-PVFISRYYELEIEEN--VNAPVELVSLNLTEH 1284
++ T+ P + ++++DK PVF + +E+ ++EN V + V ++ +
Sbjct: 1619 ILRTIEACPPQRTPVHIQVTVLDVNDKAPVFPADDFEVLVKENSAVGSVVAQITATDPDE 1678
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y I+ N +I F +D +G L + D E ++ Y ++V+A
Sbjct: 1679 GANAQIMYQIVEGNIPEI---FQMDIFSGELTSLIDLDYETRNEYVIVVQA 1726
Score = 101 bits (243), Expect = 1e-19
Identities = 98/320 (30%), Positives = 145/320 (45%), Gaps = 31/320 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G +++S V + + D ND+ PIF T Y T+ E G + L A S T
Sbjct: 1012 GSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVEEGYP-ILQLRATDSDSPTNAN 1070
Query: 133 TVPR--GLTIFKDIRAFDRDKPN---TPNSDV------HYSI-VSGNDDGHFALESSHKP 180
R G + AF+ D + T V HY++ V +D G S
Sbjct: 1071 IRYRFIGDMVAVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPRS-AT 1129
Query: 181 VLLLRKVLDYDAGDKEFQ----LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
V + VLD + +F +V + R H EIL + A D+D A + Y +I
Sbjct: 1130 VKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEIL---RVSATDRDKDSNAAVHYNII 1186
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP-LKTAQARVEIE 295
SGN R FS+DSV G + + LD +AE + L+V+A P L V ++
Sbjct: 1187 SGNSRGQFSIDSVTGEIQVVAPLDYEAERE-----YTLRVRAQDNGRPPLSNNTGIVSVQ 1241
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFS 353
+ D+NDN P F + S++E+ P G S+L + A D D G+N Y+L F
Sbjct: 1242 VTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSSDTPFI 1301
Query: 354 IDPRSGWLTVRNQTVLDREA 373
I+ +GW+TVR + LDRE+
Sbjct: 1302 INSATGWVTVR--STLDRES 1319
Score = 97.5 bits (232), Expect = 2e-18
Identities = 116/450 (25%), Positives = 190/450 (42%), Gaps = 51/450 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+ + I++++A D D N + Y +S ++ + F I+ G
Sbjct: 1155 VKENVRPHSEILRVSATDRDKDSNAAVHYNI----------ISGNS---RGQFSIDSVTG 1201
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNIS-VRVFVKDVNDHFPVFKKTWYNFNV 1054
+ V L E+E + L + A D G L++N V V V DVND+ P+F T + +V
Sbjct: 1202 EIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQASV 1261
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E+ + + A D D G NA L Y + + +D PF I+ TG ++V LDRE+ +
Sbjct: 1262 LESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSSDTPFIINSATGWVTVRSTLDRESVE 1321
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y V ARD G DVNDN P+F + A S
Sbjct: 1322 HYFFGVEARDYG-TPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVT 1380
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
+V T + G FA T G GL+ +LP Q+ + ++++
Sbjct: 1381 AVDRDVNSAVTYQIT---GGNTRNRFAIST---AGGAGLLSLALPLDYKQERRYVLTVTA 1434
Query: 1235 TAILMVTVADVPDEVEMSD--KPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKM 1290
+ + V + ++ +PVF S +Y + + E+ + V ++S + EN ++
Sbjct: 1435 SDRTLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMISATDDDVGENARI 1494
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y+L +N R ID G + L D E + TY + + A+ +P
Sbjct: 1495 T-YLLEDNIPQFR----IDSATGAITLQAELDYEDQMTYTLAITAK----DNGIPQ---- 1541
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ T Y V V + DVNDN+P+F
Sbjct: 1542 ------KSDTTY---VEVNVNDVNDNAPQF 1562
Score = 96.7 bits (230), Expect = 4e-18
Identities = 111/421 (26%), Positives = 176/421 (41%), Gaps = 39/421 (9%)
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
++L+GT I V +N + +Q I EN+ G I++L A D DS N IR
Sbjct: 1014 SRLSGTT-MVAITVSDRNDHSPIFEQTEYRETIRENVEEGYPILQLRATDSDSPTNANIR 1072
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLND 1027
Y F ++ ++ A E+ + G +V R L + L + A D G
Sbjct: 1073 YRFIGDMVA----VARAAFEIDPRSGLITTRG--VVDREL--NEHYTLQVEASDQGKEPG 1124
Query: 1028 --NISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+ +V+VF+ D ND+ P F + Y V+E + +V ATD D NA + Y
Sbjct: 1125 PRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHYN 1184
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
I ++ F I +TG + V LD E E +Y L V A+DNG D
Sbjct: 1185 IISGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTD 1244
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
VNDN P F + + E+ + + S++ I +NA + + ++D
Sbjct: 1245 VNDNPPIFVSTP--FQASVLESSPVGS----SILHIQAIDTDSGDNARLEYKLTGT-SSD 1297
Query: 1204 TDFIGNG--NGLILYSLPQRKN---------QQNLGLPSLSSTAILMVTVADVPDEVEMS 1252
T FI N + + S R++ ++ G P LS+TA + +TV DV D
Sbjct: 1298 TPFIINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVND----- 1352
Query: 1253 DKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRN 1312
+ P F+ + Y + E+ +V++ + N + Y I N R F I
Sbjct: 1353 NHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGN---TRNRFAISTAG 1409
Query: 1313 G 1313
G
Sbjct: 1410 G 1410
Score = 96.7 bits (230), Expect = 4e-18
Identities = 126/475 (26%), Positives = 203/475 (42%), Gaps = 60/475 (12%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y L + +V +T++D NDN+P F+ Y + +A VGT + V AVD D+ N
Sbjct: 1331 DYGTPPLSATASVTITVMDVNDNHPEFLQKEYYA-RLNEDAAVGTSVVTVTAVDRDV--N 1387
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERR 549
V Y + N G +S+A P+ E R+ L V ASD+ + +
Sbjct: 1388 SAVTYQITG-GNTRNRFAISTAGGAGLLSLA-LPLDYKQERRYVLTVTASDRTLHDT--- 1442
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVS 607
V I +T P F A Y V + G+ V I +D E ++
Sbjct: 1443 ---CQVHINITDANTHR----PVFQSAHYSVSVNEDSPPGSLVVMISATDDDVGENARIT 1495
Query: 608 YDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATV 664
Y L E+ +P F ++ +G IT+ +L ++ Y A+ ++N S T V
Sbjct: 1496 YLL----EDNIPQFRIDSATGAITLQAELDYEDQMTYTL-AITAKDNGIPQKSDTTYVEV 1550
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
+V DVND L + + ++ ++ QI T+ + + G V++ N +
Sbjct: 1551 NVNDVNDNAPQFLSPRYQGSVS--EDAPPFTSVLQISATDRDA---HANGRVQYTFQNGE 1605
Query: 725 DVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D D I G + T + ++ V+ QVT+ D ND
Sbjct: 1606 DGDGDFTIEPTSGILRTIEACPPQRTPVH------------------IQVTVL--DVNDK 1645
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDEN 842
PVF +E + ENS +G+ + I ATD DEG NA MY + G E+F +D
Sbjct: 1646 APVFPADDFEVLVKENSAVGSVVAQ---ITATDPDEGANAQIMYQIVEGNIPEIFQMDIF 1702
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+G + + D LD E + Y + +V + L S A + I + D+NDN+P +
Sbjct: 1703 SGELTSLID-LDYETRNEYVI-VVQATSAPLVSRATVRIKLVDQNDNRPTLQDFQ 1755
Score = 90.6 bits (215), Expect = 3e-16
Identities = 113/457 (24%), Positives = 190/457 (41%), Gaps = 52/457 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT++I ++A D D G G++ Y + + S+D YF I+ G
Sbjct: 937 VAENQPPGTSVILMSASDPDPGDAGRVSYSMAPLM----NSRSSD------YFHIHPETG 986
Query: 1000 HVIVARSLPPESE----FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ ++L E FR+ + L+ V + V D NDH P+F++T Y +
Sbjct: 987 LITTTQTLDREHMDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIR 1046
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FI--QPSDTDLPFEISPLTGVLSVNGELDRET 1112
E + ++ ATD+D NAN+ Y FI + FEI P +G+++ G +DRE
Sbjct: 1047 ENVEEGYPILQLRATDSDSPTNANIRYRFIGDMVAVARAAFEIDPRSGLITTRGVVDREL 1106
Query: 1113 EDKYILTVVARDNGXX-XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK-----HPEAD 1166
+ Y L V A D G D NDN P+F ++ K H E
Sbjct: 1107 NEHYTLQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEIL 1166
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
+S + + V+ I N+ ++ V + + + R Q+
Sbjct: 1167 RVSATDRDKDSNAAVHYNIISGNSRGQFSIDSV-TGEIQVVAPLDYEAEREYTLRVRAQD 1225
Query: 1227 LGLPSLS-STAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTE 1283
G P LS +T I+ V V DV D + P+F+S ++ + E+ V + + + T+
Sbjct: 1226 NGRPPLSNNTGIVSVQVTDVND-----NPPIFVSTPFQASVLESSPVGSSILHIQAIDTD 1280
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
+N ++ Y + T F+I+ G + + + DRE + Y E + Y
Sbjct: 1281 SGDNARLEYKL---TGTSSDTPFIINSATGWVTVRSTLDRESVEHY--FFGVEARDYGTP 1335
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
P++ V + + DVNDN P+F
Sbjct: 1336 ------PLSA---------TASVTITVMDVNDNHPEF 1357
Score = 87.0 bits (206), Expect = 3e-15
Identities = 95/327 (29%), Positives = 149/327 (45%), Gaps = 48/327 (14%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D+G A + Y L+ N + F +DS G++ L+ ELD + + T+ L +
Sbjct: 1481 ISATDDDVGENARITY-LLEDNIPQ-FRIDSATGAITLQAELDYEDQM-----TYTLAIT 1533
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K+ VE+ + D+NDN P+F Y S+ E+ P SVLQ+ ATD+D
Sbjct: 1534 AKDNGIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHA 1593
Query: 338 NG--EFTYQL-DDPKGAFSIDPRSGWL-TVR-----------NQTVLDREAHSSL----R 378
NG ++T+Q +D G F+I+P SG L T+ TVLD + +
Sbjct: 1594 NGRVQYTFQNGEDGDGDFTIEPTSGILRTIEACPPQRTPVHIQVTVLDVNDKAPVFPADD 1653
Query: 379 MKVYAKETN------PSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGT----- 427
+V KE + + T D A+ Q +E N P +F ++ +
Sbjct: 1654 FEVLVKENSAVGSVVAQITATDPDEGANAQIMYQIVEGNIPEIFQMDIFSGELTSLIDLD 1713
Query: 428 -KTEN-----IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY--EF-SMKSNAKVGTV 478
+T N ++ L+S V + L+D NDN P + F S +SN+ V
Sbjct: 1714 YETRNEYVIVVQATSAPLVSRATVRIKLVDQNDNRPTLQDFQIIFNNFVSNRSNSFPSGV 1773
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNL 505
IG++ A DPD+ + Y + R + L
Sbjct: 1774 IGRIPAHDPDVSDR--LYYTIDRGNEL 1798
Score = 83.0 bits (196), Expect = 6e-14
Identities = 56/168 (33%), Positives = 86/168 (51%), Gaps = 10/168 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D V + + Y++ GN R F++ + G+ L L LD + Q +VL V
Sbjct: 1379 VTAVDRD--VNSAVTYQITGGNTRNRFAISTAGGAGLLSLALPLDYK---QERRYVLTVT 1433
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS T Q V I + D N + P F+ Y++S+ E+ P G V+ + ATD D GE
Sbjct: 1434 ASD-RTLHDTCQ--VHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMISATDDDVGE 1490
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N TY L+D F ID +G +T+ Q LD E + + + AK+
Sbjct: 1491 NARITYLLEDNIPQFRIDSATGAITL--QAELDYEDQMTYTLAITAKD 1536
Score = 70.9 bits (166), Expect = 2e-10
Identities = 76/314 (24%), Positives = 132/314 (42%), Gaps = 18/314 (5%)
Query: 158 DVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE- 216
D+HY V+ D G L + ++ V D + F+ R + E +P
Sbjct: 1000 DLHYFRVTATDYGSSRLSGT---TMVAITVSDRNDHSPIFEQTEYRETIRENVEEGYPIL 1056
Query: 217 PIHAIDQDLGVGATLRYELISGN---DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D D A +RY I R F +D +G + +D + + +
Sbjct: 1057 QLRATDSDSPTNANIRYRFIGDMVAVARAAFEIDPRSGLITTRGVVDRELNEH-----YT 1111
Query: 274 LQVQAS-QLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
LQV+AS Q P ++A +V I +LD NDN+P+F Y +++ EN+ +L+V AT
Sbjct: 1112 LQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRVSAT 1171
Query: 332 DKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D+D+ N Y + + +G FSID +G + V + E +LR++ P
Sbjct: 1172 DRDKDSNAAVHYNIISGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPL 1231
Query: 390 VVGTFADSQRIAKWR-RQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
T S ++ P+ + P + + + VG+ +I+ D +E
Sbjct: 1232 SNNTGIVSVQVTDVNDNPPIFVSTPFQ-ASVLESSPVGSSILHIQAIDTDSGDNARLEYK 1290
Query: 449 LLDANDNNPVFVPS 462
L + + P + S
Sbjct: 1291 LTGTSSDTPFIINS 1304
Score = 65.3 bits (152), Expect = 1e-08
Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 10/130 (7%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
LD EH + +V A+ + + V I + D ND+ P FE Y +I EN+
Sbjct: 994 LDREH---MDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVE 1050
Query: 321 NGFSVLQVMATDKDQGENGEFTYQ-LDD----PKGAFSIDPRSGWLTVRNQTVLDREAHS 375
G+ +LQ+ ATD D N Y+ + D + AF IDPRSG +T R V+DRE +
Sbjct: 1051 EGYPILQLRATDSDSPTNANIRYRFIGDMVAVARAAFEIDPRSGLITTRG--VVDRELNE 1108
Query: 376 SLRMKVYAKE 385
++V A +
Sbjct: 1109 HYTLQVEASD 1118
Score = 61.7 bits (143), Expect = 2e-07
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA-EHNLQANTFVLQV 276
I AID D G A L Y+L + F ++S G + + LD ++ EH + V
Sbjct: 1274 IQAIDTDSGDNARLEYKLTGTSSDTPFIINSATGWVTVRSTLDRESVEH------YFFGV 1327
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+A P +A A V I ++D+NDN PEF Y + E+ G SV+ V A D+D
Sbjct: 1328 EARDYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRD-- 1385
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSG 359
N TYQ+ + + F+I G
Sbjct: 1386 VNSAVTYQITGGNTRNRFAISTAGG 1410
Score = 60.1 bits (139), Expect = 5e-07
Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 16/203 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V+++VT+LD ND PVF P++ +E +K N+ VG+V+ ++ A DPD G N ++Y +
Sbjct: 1633 VHIQVTVLDVNDKAPVF-PADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQIVEG 1691
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ I F+++ +G ++ E R + + V+A+ P S A V I++
Sbjct: 1692 N---IPEIFQMDIFSGELTSLIDLDYETRNEYVIVVQATSAPL------VSRATVRIKLV 1742
Query: 561 RGTKGNKPDIPDFMGAPYEFWVG-SNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N+P + DF F SN +G+I +D + + Y + G E +
Sbjct: 1743 -DQNDNRPTLQDFQIIFNNFVSNRSNSFPSGVIGRIPAHDPDVSDRLYYTIDRGNELHL- 1800
Query: 620 FAVEERSGVITVVDDLSRYNRPM 642
+ SG I + L NRP+
Sbjct: 1801 LLLNHTSGEIRLSRKLDN-NRPL 1822
Score = 58.4 bits (135), Expect = 1e-06
Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 40/233 (17%)
Query: 930 DVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYIPPSKL 981
DV+ P FL P E+ P T++++++A D D+ NG+++Y F N E
Sbjct: 1554 DVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGE-------- 1605
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
D F I G + + PP+ + ++V V DVND
Sbjct: 1606 DGDG-----DFTIEPTSGILRTIEACPPQ---------------RTPVHIQVTVLDVNDK 1645
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
PVF + V+E V+ ++ ATD D G NA + Y I + F++ +G
Sbjct: 1646 APVFPADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQIVEGNIPEIFQMDIFSGE 1705
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
L+ +LD ET ++Y++ V A D NDN P F
Sbjct: 1706 LTSLIDLDYETRNEYVIVVQA----TSAPLVSRATVRIKLVDQNDNRPTLQDF 1754
Score = 38.7 bits (86), Expect = 1.2
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPKGAFSIDPRS 358
P F Y + + EN P G SV+ + A+D D G+ G +Y + F I P +
Sbjct: 926 PFFPQYNYQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSMAPLMNSRSSDYFHIHPET 985
Query: 359 GWLTVRNQTVLDRE 372
G +T QT LDRE
Sbjct: 986 GLITT-TQT-LDRE 997
>UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia
franciscana|Rep: Af1-cadherin - Artemia sanfranciscana
(Brine shrimp) (Artemia franciscana)
Length = 1566
Score = 119 bits (286), Expect = 7e-25
Identities = 132/490 (26%), Positives = 220/490 (44%), Gaps = 38/490 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
VT+ D NDN P+F N Y ++ ++KV + +V A D D G+N + Y L+ + +
Sbjct: 209 VTITDKNDNAPIF-DKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSLRANRDES 267
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEVTRGTK 564
F+I+P +G + + ++ E F V A+ PS + A V I+V +
Sbjct: 268 DLDYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNE--TTAQVNIKVVSSNR 325
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV----PF 620
P+ + + N G + +R E+ V + L++G E F
Sbjct: 326 -RAPEFTEVPDHIIDIEESFN-DFGRPIVTLRAVSNIEKPVVYFSLVNGQTEDTNKEETF 383
Query: 621 AVEER-SGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLK 678
+ ER +G + + + +++ + +Q + ++S T + V+D NDE +
Sbjct: 384 RLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETIVRLRVLDSNDEIPSFID 443
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGT 737
++ ENSA Q F + +I +GT + TD +I +E G
Sbjct: 444 IESGSVL----ENSA----VQTFVLRIRAIDKDGTSPNNKVTYRLLSNTDTFSIDSETGE 495
Query: 738 IFTQKPLDREKRDVYRMTVIAEFN-KGVISGAGI---YQVTIYIE--DENDNPPVFEHAT 791
I T K LDRE+ Y +TV A+ + G+ YQ +E D+NDNPP FE T
Sbjct: 496 IRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPRFEQPT 555
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIG 850
Y I E++ I ++ +I+ T D+ A+ Y + G F V+E +GV++ +
Sbjct: 556 YNAEIAEDADINSK-----VIEVTARDKDDFAVIRYDITDGNVDNAFMVEEKSGVIR-VN 609
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR--IHRET 908
+ LD EK Y L + A D G S EA + + I + NDN P F ++ VR I E
Sbjct: 610 NQLDYEKITDYYLRVRASD-GIHSDEATVHVSISNVNDNPPIFENMQNPHVVRNIIEEEK 668
Query: 909 KLNGTAGFTI 918
+ + A T+
Sbjct: 669 RPDPIAKITV 678
Score = 73.7 bits (173), Expect = 3e-11
Identities = 118/481 (24%), Positives = 201/481 (41%), Gaps = 56/481 (11%)
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
A + P F+ N E S+ GT + KV+A DPD G G V Y++ R+ + F
Sbjct: 106 AINTRPTFIKCN--ETSIPEGENAGTFVTKVEAYDPDQGPAGKVRYEIIRSQ--SAEKQF 161
Query: 512 KINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
+N TG ++ A + P E + V+A D+ + + T VT K +
Sbjct: 162 NVNSYTGEITTAKVFDRDEPKREKLLYVTVKAVDEGFPALD-----VLCTFSVTITDKND 216
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG--VPFAV 622
+ P F Y + + + +V ++ D E + ++Y L +E F +
Sbjct: 217 --NAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSLRANRDESDLDYFQI 274
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAV-ALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ +SG I +V + + Y FE V A ++ S T A V++ V+ R
Sbjct: 275 DPQSGFIKLVKAIEA-EKVDYQFELVAAARDGGTPSNETTAQVNIKVVSSNRRAPEFTEV 333
Query: 682 SPIIFHVKE--NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ------DVTDDIAIA 733
I ++E N G I + ++ V F + N Q + T +
Sbjct: 334 PDHIIDIEESFNDFGRPI-----VTLRAVSNIEKPVVYFSLVNGQTEDTNKEETFRLVER 388
Query: 734 EDGT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+GT IF + LD E Y++ + + N +S I V + + D ND P F
Sbjct: 389 ANGTMDIFLARKLDYETVSNYQLNIRVQ-NDFDVSAETI--VRLRVLDSNDEIPSFIDIE 445
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
G ++ENS + T + I+A D D N Y L + F +D TG ++ +
Sbjct: 446 -SGSVLENSAVQTFVLR---IRAIDKDGTSPNNKVTYRLL-SNTDTFSIDSETGEIRTL- 499
Query: 851 DSLDREKKIMYKLSLVARD-------TGGLSS--EAELIIMIGDENDNKPEFNQIEENSK 901
LDRE+ Y +++ A+D + GL + + + + + D+NDN P F Q N++
Sbjct: 500 KRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPRFEQPTYNAE 559
Query: 902 V 902
+
Sbjct: 560 I 560
Score = 68.9 bits (161), Expect = 1e-09
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 23/198 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE GT + K+ A D D G G++RYE + + + E + F +N G
Sbjct: 121 IPEGENAGTFVTKVEAYDPDQGPAGKVRYEI----------IRSQSAE--KQFNVNSYTG 168
Query: 1000 HVIVARSLPPESEFR-----LNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+ A+ + R + + A+D G L+ + V + D ND+ P+F K Y
Sbjct: 169 EITTAKVFDRDEPKREKLLYVTVKAVDEGFPALDVLCTFSVTITDKNDNAPIFDKNDYRE 228
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLP-FEISPLTGVLSVNGELD 1109
+ + + + +V ATD D G+NA +TY ++ + ++DL F+I P +G + + ++
Sbjct: 229 TIPQDSKVNQTVMRVAATDIDEGENARITYSLRANRDESDLDYFQIDPQSGFIKLVKAIE 288
Query: 1110 RETED-KYILTVVARDNG 1126
E D ++ L ARD G
Sbjct: 289 AEKVDYQFELVAAARDGG 306
Score = 68.1 bits (159), Expect = 2e-09
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 214 FPEPIHAIDQDLGVGATLRYELI-SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
F + A D D G +RYE+I S + K F+++S G + K D D +
Sbjct: 130 FVTKVEAYDPDQGPAGKVRYEIIRSQSAEKQFNVNSYTGEITTAKVFDRDEPK--REKLL 187
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ V+A P + + D NDN P F+ + Y +I ++ +V++V ATD
Sbjct: 188 YVTVKAVDEGFPALDVLCTFSVTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATD 247
Query: 333 KDQGENGEFTYQL-----DDPKGAFSIDPRSGWL 361
D+GEN TY L + F IDP+SG++
Sbjct: 248 IDEGENARITYSLRANRDESDLDYFQIDPQSGFI 281
Score = 65.7 bits (153), Expect = 9e-09
Identities = 56/200 (28%), Positives = 87/200 (43%), Gaps = 9/200 (4%)
Query: 191 DAGDKEFQLVIMASGKRIHKEIL--FPEPIHAIDQD-LGVGATLRYELISGNDRKLFSLD 247
D+ D+ + + SG + + F I AID+D + Y L+S D FS+D
Sbjct: 433 DSNDEIPSFIDIESGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRLLSNTDT--FSID 490
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP--LKTAQARVEIELLDLNDNLPE 305
S G + K LD + + S L + Q + ++E+LD NDN P
Sbjct: 491 SETGEIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPR 550
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
FE YN I E+ V++V A DKD + + AF ++ +SG + V N
Sbjct: 551 FEQPTYNAEIAEDADINSKVIEVTARDKDDFAVIRYDITDGNVDNAFMVEEKSGVIRVNN 610
Query: 366 QTVLDREAHSSLRMKVYAKE 385
Q LD E + ++V A +
Sbjct: 611 Q--LDYEKITDYYLRVRASD 628
Score = 65.3 bits (152), Expect = 1e-08
Identities = 85/341 (24%), Positives = 140/341 (41%), Gaps = 33/341 (9%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
+ G + + +V I D NDN PIF Y T+ + + + I
Sbjct: 194 VDEGFPALDVLCTFSVTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGEN 253
Query: 130 IPLTVP-RGLTIFKDIRAFDRDKPN----------TPNSDVHYSIVSGNDDGHFALESSH 178
+T R D+ F D + D + +V+ DG S+
Sbjct: 254 ARITYSLRANRDESDLDYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDG--GTPSNE 311
Query: 179 KPVLLLRKVLDYDAGDKEFQLV------IMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
+ KV+ + EF V I S + I+ + I++ + + +
Sbjct: 312 TTAQVNIKVVSSNRRAPEFTEVPDHIIDIEESFNDFGRPIVTLRAVSNIEKPVVYFSLVN 371
Query: 233 YELISGNDRKLFSL-DSVNGSL--FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+ N + F L + NG++ FL ++LD + N Q N ++VQ N+ +A+
Sbjct: 372 GQTEDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLN---IRVQ----NDFDVSAE 424
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLDDP 348
V + +LD ND +P F +D + S++EN VL++ A DKD N + TY+L
Sbjct: 425 TIVRLRVLDSNDEIPSF-IDIESGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRLLSN 483
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
FSID +G +R LDRE SS + V A++ PS
Sbjct: 484 TDTFSIDSETG--EIRTLKRLDREETSSYAVTVQAQDGAPS 522
Score = 50.8 bits (116), Expect = 3e-04
Identities = 72/284 (25%), Positives = 118/284 (41%), Gaps = 25/284 (8%)
Query: 886 ENDNKPE-FNQIEE-NSKVRIHRETKLN-GTAGFTIIEVKPKNKFALDVDQLGPLFLIPE 942
E+ NK E F +E N + I KL+ T + ++ +N F + + + L ++
Sbjct: 375 EDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETIVRLRVLDS 434
Query: 943 N--IPIGTTIIKLNALDLDSGLNGQIRYE-FNSEVYIPPSKLSADALEVKRYFVINERHG 999
N IP I + L+ + +R + + P +K++ L F I+ G
Sbjct: 435 NDEIPSFIDIESGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRLLSNTDTFSIDSETG 494
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLN---DNI------SVRVFVKDVNDHFPVFKKT 1048
+ + L E S + + + A DG + D + +V V D ND+ P F++
Sbjct: 495 EIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPRFEQP 554
Query: 1049 WYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
YN + E+A +V+ +V A D D A + Y I + D F + +GV+ VN +
Sbjct: 555 TYNAEIAEDADINSKVI-EVTARDKD--DFAVIRYDITDGNVDNAFMVEEKSGVIRVNNQ 611
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD E Y L V A D +VNDN P F
Sbjct: 612 LDYEKITDYYLRVRASDG----IHSDEATVHVSISNVNDNPPIF 651
Score = 40.7 bits (91), Expect = 0.30
Identities = 42/176 (23%), Positives = 79/176 (44%), Gaps = 16/176 (9%)
Query: 988 VKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
V F++ E+ G + V L E +++ L + A DG + +D +V V + +VND+ P+F
Sbjct: 593 VDNAFMVEEKSGVIRVNNQLDYEKITDYYLRVRASDGIH-SDEATVHVSISNVNDNPPIF 651
Query: 1046 KKTWYNF---NVEEAQYTRRVLGKVDATDADF---GQNANLTYFI-QPSDTDLPFEISPL 1098
+ N+ E + + K+ D D+ G+N +T+ + + F I+P
Sbjct: 652 ENMQNPHVVRNIIEEEKRPDPIAKITVRDPDWDKGGKNPYITFSLDRTGQYAKHFRITP- 710
Query: 1099 TGVLSVNGELDRETEDKY---ILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSP 1149
G L ++ +DR+ + Y + ++A D D+NDN+P
Sbjct: 711 EGELFLDKGIDRDPPNGYPQARVNIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAP 766
Score = 39.1 bits (87), Expect = 0.92
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 5/111 (4%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE-LEIEENVNAPVELVSLNLTEHYE 1286
G P+L VT+ D D + DK + Y E + + VN V V+ + E
Sbjct: 197 GFPALDVLCTFSVTITDKNDNAPIFDK----NDYRETIPQDSKVNQTVMRVAATDIDEGE 252
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
N ++ Y + D F IDP++G + LV++ + E D +V A R
Sbjct: 253 NARITYSLRANRDESDLDYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAAR 303
Score = 37.9 bits (84), Expect = 2.1
Identities = 29/126 (23%), Positives = 61/126 (48%), Gaps = 13/126 (10%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+ + KN A D+ IP++ + T++++ A D+D G N +I Y
Sbjct: 209 VTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSL-------- 260
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFV 1035
+ + D ++ YF I+ + G + + +++ E +F L +A DGG ++ + +V +
Sbjct: 261 -RANRDESDLD-YFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNETTAQVNI 318
Query: 1036 KDVNDH 1041
K V+ +
Sbjct: 319 KVVSSN 324
>UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type receptor
3 precursor; n=60; Eukaryota|Rep: Cadherin EGF LAG
seven-pass G-type receptor 3 precursor - Homo sapiens
(Human)
Length = 3312
Score = 118 bits (285), Expect = 9e-25
Identities = 134/487 (27%), Positives = 217/487 (44%), Gaps = 39/487 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +V VT+LD NDN P F Y + +A VGT + V AVD D N + Y
Sbjct: 736 LSASASVTVTVLDVNDNRPEFTMKE-YHLRLNEDAAVGTSVVSVTAVDRDA--NSAISYQ 792
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR-YSLAVVTI 557
+ T T + F I+ G V + L+ + + + S+R + V I
Sbjct: 793 I--TGGNT-RNRFAISTQGGVGLVTLALPLDYKQERYFKLV---LTASDRALHDHCYVHI 846
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY--E 615
+T P F A Y V + +G+++ I +D +DV + Y E
Sbjct: 847 NITDANTHR----PVFQSAHYSVSVNEDRPMGSTIVVISASD----DDVGENARITYLLE 898
Query: 616 EGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVNDE 672
+ +P F ++ SG IT+ L ++ Y A+ ++N + T V V DVND
Sbjct: 899 DNLPQFRIDADSGAITLQAPLDYEDQVTYTL-AITARDNGIPQKADTTYVEVMVNDVNDN 957
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ ++ ++ ++ ++ QI T+ + + G V++ N +D D I
Sbjct: 958 APQFVASHYTGLVS--EDAPPFTSVLQISATDRDA---HANGRVQYTFQNGEDGDGDFTI 1012
Query: 733 AE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G + T + LDRE VY +T A ++GV + + ++D NDN PVF
Sbjct: 1013 EPTSGIVRTVRRLDREAVSVYELTAYA-VDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEE 1071
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIG 850
+E + ENS +G+ + I A D DEG NA MY + G E+F +D +G + +
Sbjct: 1072 FEVRVKENSIVGSVVAQ---ITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALI 1128
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN--QIEENSKVRIHRET 908
D LD E + Y + +V + L S A + + + D+NDN P N QI N+ V +T
Sbjct: 1129 D-LDYEARQEYVI-VVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDT 1186
Query: 909 KLNGTAG 915
+G G
Sbjct: 1187 FPSGIIG 1193
Score = 109 bits (261), Expect = 8e-22
Identities = 118/458 (25%), Positives = 188/458 (41%), Gaps = 27/458 (5%)
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
A + +P F P Y+ + N GT + +V A DPD G+ G ++Y L N F
Sbjct: 318 AANRHPQF-PQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELF 376
Query: 512 KINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPD 569
I+P +G + A + E RH L V A D +P ++ VT+
Sbjct: 377 SIDPQSGLIRTAAALDRESMERHYLRVTAQDH-GSPRLSATTMVAVTV------ADRNDH 429
Query: 570 IPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL----HGYEEGVPFAVE 623
P F A Y + NV G + Q+R DA ++ Y + F ++
Sbjct: 430 SPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEID 489
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGAHS 682
RSG+I+ + R + Y+ V + +ATV V + V DE + +
Sbjct: 490 PRSGLISTSGRVDREHMESYEL-VVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEK 548
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
+ V+E+ + + + + G V + I + + G I
Sbjct: 549 RYVAQVREDVRPHTV--VLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVA 606
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLD E Y + + A+ +I + D ND+ P+F ++ ++EN+ +
Sbjct: 607 PLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPL 666
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGDSLDREKKIMY 861
G + I+A DAD G NA Y+L G + F ++ TG V G LDRE Y
Sbjct: 667 GHSVIH---IQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSG-PLDRESVEHY 722
Query: 862 KLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
+ ARD G LS+ A + + + D NDN+PEF E
Sbjct: 723 FFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKE 760
Score = 103 bits (246), Expect = 5e-20
Identities = 119/481 (24%), Positives = 198/481 (41%), Gaps = 33/481 (6%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + V VT+ D ND++PVF + Y +++ N + G I +++A D D N + Y
Sbjct: 412 RLSATTMVAVTVADRNDHSPVFEQAQ-YRETLRENVEEGYPILQLRATDGDAPPNANLRY 470
Query: 498 DL--QRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
+ + F+I+P +G +S + E + L VEASDQ P R A
Sbjct: 471 RFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRS---A 527
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V + +T + P F Y V +V T V ++ D + + V Y+++
Sbjct: 528 TVRVHIT--VLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNII 585
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN---ATVHVVD 668
G G FA++ +G I VV L Y + Q+ + N A++ VVD
Sbjct: 586 SGNSRG-HFAIDSLTGEIQVVAPLDFEAEREYALR-IRAQDAGRPPLSNNTGLASIQVVD 643
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ND + + +P V EN A +G + H + + + T
Sbjct: 644 INDHIPIFVS---TPFQVSVLEN---APLGHSVIHIQAVDADHGENARLEYSLTGVAPDT 697
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ + G + PLDRE + Y V A + G + VT+ + D NDN P F
Sbjct: 698 PFVINSATGWVSVSGPLDRESVEHYFFGVEAR-DHGSPPLSASASVTVTVLDVNDNRPEF 756
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV- 845
Y + E++ +GT +++ T D N+ Y + G + F + GV
Sbjct: 757 TMKEYHLRLNEDAAVGT-----SVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVG 811
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+ + LD +++ +KL L A D L + I I D N ++P F + V
Sbjct: 812 LVTLALPLDYKQERYFKLVLTASDR-ALHDHCYVHINITDANTHRPVFQSAHYSVSVNED 870
Query: 906 R 906
R
Sbjct: 871 R 871
Score = 99.5 bits (237), Expect = 6e-19
Identities = 123/467 (26%), Positives = 201/467 (43%), Gaps = 66/467 (14%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+PEN GT ++++ A D D+G G++ VY + +++ +LE+ F I+ +
Sbjct: 333 LVPENEAAGTAVLRVVAQDPDAGEAGRL-------VYSLAALMNSRSLEL---FSIDPQS 382
Query: 999 GHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + A +L ES R L ++A D G+ L+ V V V D NDH PVF++ Y +
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETL 442
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQP----SDTDLPFEISPLTGVLSVNGELD 1109
E + ++ ATD D NANL Y F+ P + FEI P +G++S +G +D
Sbjct: 443 RENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVD 502
Query: 1110 RETEDKYILTVVARDNGXX-XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
RE + Y L V A D G D NDN+P+F + + + +++
Sbjct: 503 REHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVR----EDV 558
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP--------- 1219
H V+ + + N + + + I + G I P
Sbjct: 559 RPHTV--VLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREY 616
Query: 1220 -QRKNQQNLGLPSLS-STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
R Q+ G P LS +T + + V D+ D + P+F+S +++ + EN ++
Sbjct: 617 ALRIRAQDAGRPPLSNNTGLASIQVVDINDHI-----PIFVSTPFQVSVLENAPLGHSVI 671
Query: 1278 SLNL--TEHYENFKMRYYILN-ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+ +H EN ++ Y + DT FVI+ G + + DRE + Y V
Sbjct: 672 HIQAVDADHGENARLEYSLTGVAPDT----PFVINSATGWVSVSGPLDRESVEHYFFGVE 727
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
A H P++ V V + DVNDN P+FT
Sbjct: 728 AR--------DHGSPPLSA---------SASVTVTVLDVNDNRPEFT 757
Score = 98.3 bits (234), Expect = 1e-18
Identities = 119/497 (23%), Positives = 205/497 (41%), Gaps = 56/497 (11%)
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
++ Y L+ VA DT + + A + + D + + R H L+ +A T
Sbjct: 685 RLEYSLTGVAPDTPFVINSATGWVSVSGPLDRE-SVEHYFFGVEARDHGSPPLSASASVT 743
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+ V N + + E+ +GT+++ + A+D D+ N I Y+
Sbjct: 744 VT-VLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--NSAISYQITGG---- 796
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLP----PESEFRLNISALDGGNLNDNISVRV 1033
+ F I+ + G +V +LP E F+L ++A D L+D+ V +
Sbjct: 797 ---------NTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA-LHDHCYVHI 846
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
+ D N H PVF+ Y+ +V E + + + A+D D G+NA +TY ++ D F
Sbjct: 847 NITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLE--DNLPQF 904
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
I +G +++ LD E + Y L + ARDNG DVNDN+P+F A
Sbjct: 905 RIDADSGAITLQAPLDYEDQVTYTLAITARDNG-IPQKADTTYVEVMVNDVNDNAPQFVA 963
Query: 1154 --FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
+ L+ P F SV+ I N + T D DF
Sbjct: 964 SHYTGLVSEDAPP--------FTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPT 1015
Query: 1212 GLILYSLPQRKNQQ-----------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
I+ ++ + + + G+P L + + V V DV D + PVF +
Sbjct: 1016 SGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVND-----NAPVFPAE 1070
Query: 1261 YYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
+E+ ++EN V + V ++ + N + Y I+ N I F +D +G L +
Sbjct: 1071 EFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGN---IPELFQMDIFSGELTAL 1127
Query: 1319 RSPDREVKDTYEVIVRA 1335
D E + Y ++V+A
Sbjct: 1128 IDLDYEARQEYVIVVQA 1144
Score = 96.7 bits (230), Expect = 4e-18
Identities = 115/427 (26%), Positives = 176/427 (41%), Gaps = 43/427 (10%)
Query: 905 HRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
H +L+ T + V +N + +Q + EN+ G I++L A D D+ N
Sbjct: 408 HGSPRLSATT-MVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNA 466
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDG 1022
+RY F PP+ +A A F I+ R G + + + E + L + A D
Sbjct: 467 NLRYRFVG----PPAARAAAAAA----FEIDPRSGLISTSGRVDREHMESYELVVEASDQ 518
Query: 1023 GN----LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
G + + V + V D ND+ P F + Y V E V+ +V ATD D N
Sbjct: 519 GQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANG 578
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
+ Y I ++ F I LTG + V LD E E +Y L + A+D G
Sbjct: 579 LVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLAS 638
Query: 1139 XXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF-ESVMMIPVYKATIEENAPIGTTVA 1197
D+ND+ P F + + L N SV+ I A ENA + ++
Sbjct: 639 IQVVDINDHIPIFVSTPF-------QVSVLENAPLGHSVIHIQAVDADHGENARLEYSLT 691
Query: 1198 KVFANDTDF-IGNGNGLILYSLP-QRKNQQNL---------GLPSLSSTAILMVTVADVP 1246
V A DT F I + G + S P R++ ++ G P LS++A + VTV DV
Sbjct: 692 GV-APDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVN 750
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTF 1306
D ++P F + Y L + E+ +VS+ + N + Y I N R F
Sbjct: 751 D-----NRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGN---TRNRF 802
Query: 1307 VIDPRNG 1313
I + G
Sbjct: 803 AISTQGG 809
Score = 93.5 bits (222), Expect = 4e-17
Identities = 52/159 (32%), Positives = 83/159 (52%), Gaps = 10/159 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D + Y +ISGN R F++DS+ G + + LD +AE + L+++
Sbjct: 567 VTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAERE-----YALRIR 621
Query: 278 ASQLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P L I+++D+ND++P F + +S++EN P G SV+ + A D D G
Sbjct: 622 AQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHG 681
Query: 337 ENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREA 373
EN Y L P F I+ +GW++V LDRE+
Sbjct: 682 ENARLEYSLTGVAPDTPFVINSATGWVSVSGP--LDRES 718
Score = 89.8 bits (213), Expect = 5e-16
Identities = 194/834 (23%), Positives = 317/834 (38%), Gaps = 113/834 (13%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDL--LHGYEEGVPFAVEERS 626
P F Y+ V N GT+V ++ D A E + Y L L F+++ +S
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
G+I L R + + A + LS T V V D ND V + + +
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETL 442
Query: 686 FHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFTQ 741
+EN G I Q+ T+ N RF+ A D G I T
Sbjct: 443 ---RENVEEGYPILQLRATD-GDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTS 498
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISG--AGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+DRE + Y + V A ++G G + +V I + DENDN P F Y + E+
Sbjct: 499 GRVDREHMESYELVVEAS-DQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVRED 557
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ T +++ T D +A G +++ F DSL E ++
Sbjct: 558 VRPHTV-----VLRVTATDRDKDA--------NGLVHYNIISGNSRGHFAIDSLTGEIQV 604
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTII 919
+ L A E E + I ++ +P + N+ G A ++
Sbjct: 605 VAPLDFEA--------EREYALRIRAQDAGRPP---LSNNT-----------GLASIQVV 642
Query: 920 EVKPKNKFALDVD-QLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
++ + Q+ L EN P+G ++I + A+D D G N ++ Y P
Sbjct: 643 DINDHIPIFVSTPFQVSVL----ENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTP 698
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVF 1034
FVIN G V V+ L ES + + A D G+ L+ + SV V
Sbjct: 699 -------------FVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVT 745
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
V DVND+ P F Y+ + E + V A D D N+ ++Y I +T F
Sbjct: 746 VLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRD--ANSAISYQITGGNTRNRFA 803
Query: 1095 ISPL--TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
IS G++++ LD + E +Y V+ + D N + P F
Sbjct: 804 ISTQGGVGLVTLALPLDYKQE-RYFKLVLTASD---RALHDHCYVHINITDANTHRPVFQ 859
Query: 1153 A--FDELLEWKHPEADELS--NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG 1208
+ + + P + + + + V +E+N P A A
Sbjct: 860 SAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPL 919
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
+ + Y+L G+P + T + V V DV D P F++ +Y + E
Sbjct: 920 DYEDQVTYTLAITARDN--GIPQKADTTYVEVMVNDVNDNA-----PQFVASHYTGLVSE 972
Query: 1269 NVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
+ ++ ++ T+ + N +++Y N D D F I+P +G + VR DRE
Sbjct: 973 DAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGD--GDFTIEPTSGIVRTVRRLDREAV 1030
Query: 1327 DTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
YE+ A R +P + PV+ + V ++DVNDN+P F
Sbjct: 1031 SVYELTAYA----VDRGVPPLRTPVS-------------IQVMVQDVNDNAPVF 1067
Score = 83.8 bits (198), Expect = 3e-14
Identities = 80/290 (27%), Positives = 134/290 (46%), Gaps = 27/290 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D+G A + Y L+ N + F +D+ +G++ L+ LD + + T+ L +
Sbjct: 880 ISASDDDVGENARITY-LLEDNLPQ-FRIDADSGAITLQAPLDYEDQV-----TYTLAIT 932
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P K VE+ + D+NDN P+F Y + E+ P SVLQ+ ATD+D
Sbjct: 933 ARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHA 992
Query: 338 NG--EFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
NG ++T+Q +D G F+I+P SG VR LDREA S + YA + + T
Sbjct: 993 NGRVQYTFQNGEDGDGDFTIEPTSG--IVRTVRRLDREAVSVYELTAYAVDRGVPPLRTP 1050
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
Q + Q + NAP VFP + + + ++ V ++T +D ++
Sbjct: 1051 VSIQVMV----QDVNDNAP------VFP----AEEFEVRVKENSIVGSVVAQITAVDPDE 1096
Query: 455 NNPVFVPSNLYEFSMKSNAKVGTVIGKVKA-VDPDLGQNGMVLYDLQRTS 503
+ + E ++ ++ G++ A +D D + +Q TS
Sbjct: 1097 GPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATS 1146
Score = 83.0 bits (196), Expect = 6e-14
Identities = 82/311 (26%), Positives = 137/311 (44%), Gaps = 22/311 (7%)
Query: 84 TVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIGPS--LTIPLT--VPRG 137
++ + D+ND++PIF+ TP+ V+V E P G + A G + L LT P
Sbjct: 638 SIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDT 697
Query: 138 LTIFKDIRAF-DRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
+ + P S HY V D G L +S + VLD +
Sbjct: 698 PFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVT---VLDVNDNRP 754
Query: 196 EFQLVIMASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
EF + R++++ + ++ D + + Y++ GN R F++ + G
Sbjct: 755 EFTM--KEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGL 812
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
+ L LD + Q F L + AS + L V I + D N + P F+ Y++S
Sbjct: 813 VTLALPLDYK---QERYFKLVLTAS--DRALHD-HCYVHINITDANTHRPVFQSAHYSVS 866
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
+ E+ P G +++ + A+D D GEN TY L+D F ID SG +T+ Q LD E
Sbjct: 867 VNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITL--QAPLDYEDQ 924
Query: 375 SSLRMKVYAKE 385
+ + + A++
Sbjct: 925 VTYTLAITARD 935
Score = 77.8 bits (183), Expect = 2e-12
Identities = 65/224 (29%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYIPPSKLSADALEVKRYFVINER 997
L+ E+ P T++++++A D D+ NG+++Y F N E D F I
Sbjct: 969 LVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGE--------DGDG-----DFTIEPT 1015
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V R L E S + L A+D G L +S++V V+DVND+ PVF +
Sbjct: 1016 SGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVR 1075
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V+E V+ ++ A D D G NA++ Y I + F++ +G L+ +LD E
Sbjct: 1076 VKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEAR 1135
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
+Y++ V A D NDNSP F L
Sbjct: 1136 QEYVIVVQA----TSAPLVSRATVHVRLVDQNDNSPVLNNFQIL 1175
Score = 76.6 bits (180), Expect = 5e-12
Identities = 107/452 (23%), Positives = 185/452 (40%), Gaps = 44/452 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L V + + DAN + PVF ++ Y S+ + +G+ I + A D D+G+N +
Sbjct: 835 DRALHDHCYVHINITDANTHRPVFQSAH-YSVSVNEDRPMGSTIVVISASDDDVGENARI 893
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y L+ NL F+I+ ++G +++ ++P+ + A N ++ V
Sbjct: 894 TYLLE--DNL---PQFRIDADSGAITL-QAPLDYEDQVTYTLAITARDNGIPQKADTTYV 947
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
+ V + P F+ + Y V + TSV QI DA V Y +G
Sbjct: 948 EVMV----NDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNG 1003
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDE 672
+ F +E SG++ V L R +Y+ A A+ L + V V DVND
Sbjct: 1004 EDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDN 1063
Query: 673 RGVLLKGAHSPIIFHVKENS-AGAAIGQIFHT------NMSSIYGNGTGNVRFLIANQQD 725
V VKENS G+ + QI N +Y GN+ L Q D
Sbjct: 1064 APVF---PAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELF--QMD 1118
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ G + LD E R Y + V+ + ++S A ++ + + D+NDN P
Sbjct: 1119 IF-------SGELTALIDLDYEARQEY-VIVVQATSAPLVSRATVH---VRLVDQNDNSP 1167
Query: 786 VFEH--ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
V + + ++ S + I A D D + + + G ++ V++ +
Sbjct: 1168 VLNNFQILFNNYVSNRSDTFPS-GIIGRIPAYDPDVSDHLFYSFER-GNELQLLVVNQTS 1225
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
G ++ + LD + ++ S++ T GL S
Sbjct: 1226 GELR-LSRKLDNNRPLV--ASMLVTVTDGLHS 1254
Score = 68.5 bits (160), Expect = 1e-09
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 17/176 (9%)
Query: 220 AIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
A D D G L Y L ++ +LFS+D +G + LD ++ L+V
Sbjct: 349 AQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIRTAAALDRESMER-----HYLRV 403
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A +P +A V + + D ND+ P FE Y ++ EN+ G+ +LQ+ ATD D
Sbjct: 404 TAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAP 463
Query: 337 ENGEFTYQLDDP-------KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y+ P AF IDPRSG ++ + +DRE S + V A +
Sbjct: 464 PNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGR--VDREHMESYELVVEASD 517
Score = 58.8 bits (136), Expect = 1e-06
Identities = 65/236 (27%), Positives = 105/236 (44%), Gaps = 20/236 (8%)
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE-PI 218
HY V+ D G L ++ ++ V D + F+ R + E +P +
Sbjct: 399 HYLRVTAQDHGSPRLSAT---TMVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQL 455
Query: 219 HAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
A D D A LRY + + F +D +G + +D EH ++
Sbjct: 456 RATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVD--REH---MESYE 510
Query: 274 LQVQAS-QLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
L V+AS Q P ++A RV I +LD NDN P+F Y + E++ VL+V AT
Sbjct: 511 LVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTAT 570
Query: 332 DKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+D+ NG Y + + +G F+ID +G + V LD EA +++ A++
Sbjct: 571 DRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQV--VAPLDFEAEREYALRIRAQD 624
Score = 57.2 bits (132), Expect = 3e-06
Identities = 96/408 (23%), Positives = 161/408 (39%), Gaps = 62/408 (15%)
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP--SDTDL 1091
F + N H P F + Y V E + + +V A D D G+ L Y + + L
Sbjct: 315 FRRAANRH-PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSL 373
Query: 1092 P-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I P +G++ LDRE+ +++ L V A+D+G D ND+SP
Sbjct: 374 ELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHG-SPRLSATTMVAVTVADRNDHSPV 432
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP--------IGTTVAKVFAN 1202
F E +++ E N E I +AT + P +G A+ A
Sbjct: 433 F----EQAQYR-----ETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAA 483
Query: 1203 DTDFIGNGNGLI------------LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
I +GLI Y L + Q S+T + +TV D E
Sbjct: 484 AAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLD-----E 538
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVI 1308
+ P F + Y ++ E+V ++ + T+ + N + Y I++ N R F I
Sbjct: 539 NDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNS---RGHFAI 595
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVV 1368
D G + +V D E + Y + +RA Q R P++ + G+ +
Sbjct: 596 DSLTGEIQVVAPLDFEAEREYALRIRA--QDAGRP------PLSNNT--GLAS------I 639
Query: 1369 RIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASR 1416
++ D+ND+ P F + P ++ AP G+ V+ ++ H +R
Sbjct: 640 QVVDINDHIPIFV--STPFQVSVLENAPLGHSVIHIQAVDADHGENAR 685
Score = 54.0 bits (124), Expect = 3e-05
Identities = 45/169 (26%), Positives = 85/169 (50%), Gaps = 14/169 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A+D D G A + Y+++ GN +LF +D +G L +LD +A +V+ VQ
Sbjct: 1089 ITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQE-----YVIVVQ 1143
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLP---EFEVDFYNI--SIVENLPNGFSVLQVMATD 332
A+ PL ++A V + L+D NDN P F++ F N + + P+G + ++ A D
Sbjct: 1144 ATSA--PL-VSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGI-IGRIPAYD 1199
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
D ++ ++++ + ++ SG L + + +R +S+ + V
Sbjct: 1200 PDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTV 1248
Score = 46.4 bits (105), Expect = 0.006
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-----FSIDPRS 358
P+F Y + EN G +VL+V+A D D GE G Y L + FSIDP+S
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G +R LDRE+ ++V A++
Sbjct: 383 G--LIRTAAALDRESMERHYLRVTAQD 407
Score = 44.0 bits (99), Expect = 0.032
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 4/65 (6%)
Query: 139 TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ 198
T+ + A DRDK N VHY+I+SGN GHFA++S + ++ LD++A ++E+
Sbjct: 562 TVVLRVTATDRDKD--ANGLVHYNIISGNSRGHFAIDSLTGEIQVVAP-LDFEA-EREYA 617
Query: 199 LVIMA 203
L I A
Sbjct: 618 LRIRA 622
>UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF13750, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 728
Score = 118 bits (283), Expect = 2e-24
Identities = 129/471 (27%), Positives = 206/471 (43%), Gaps = 45/471 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
++++V +LDANDN P F S LY+ + NA G+ + ++ A D D G NG V+Y +
Sbjct: 199 LSIDVNVLDANDNTPTFSKS-LYKARVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKR 257
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVT 560
N F I+ +G V+V + E + A + V+A D+ +P L V ++V
Sbjct: 258 GNFNPADVFVIDAESGEVTVKAALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDV- 316
Query: 561 RGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGV 618
N P+I + P V + IG++V + V D +N + + G V
Sbjct: 317 ---NDNAPEIAVTSLVNP----VKEDAEIGSAVALVTVTDKDSGKNGKTRTEIVG---SV 366
Query: 619 PFAV--EERSGVITVVD-DLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERG 674
PF + ++ VVD L R Y A E + LS VHV DVND
Sbjct: 367 PFKLLSNYKNYYSLVVDGPLDREKCSSYSITITAADEGSPPLSSTILVIVHVADVNDNAP 426
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIANQQDVTDD---- 729
+ + +VKENS +G + HT + V + + + +T
Sbjct: 427 AF---SSPEVNIYVKENS---PVGALIHTITATDPDKEENAIVTYSVMHGSRITQQKTWL 480
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I+I +E G I + + D E+ ++ V A + GV + + I+I D NDN P+F+
Sbjct: 481 ISINSETGDIVSLQSFDYEELKTFQFQVQAT-DSGVPPLSSTTVIQIHISDVNDNAPLFK 539
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG------EGKEMFDVDEN 842
+ ENS +G I I D D NA Y+L + +++ +
Sbjct: 540 EPVVNVHVKENSPVGITIL---TITTADLDREENAKVTYSLIDGLFNSISVRSAVNINSD 596
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
TG + + S D E+ ++ + A D+G LSS + + I DENDN P
Sbjct: 597 TGDITIL-QSFDYEEVKTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNP 646
Score = 103 bits (248), Expect = 3e-20
Identities = 172/699 (24%), Positives = 288/699 (41%), Gaps = 92/699 (13%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T N+E + +EV + D NDN PVF+ + Y ++ + G AVD D
Sbjct: 76 TLNLEAILSDPVVLHRIEVVISDLNDNAPVFLEKS-YSLNISEWSPTGERFLLPLAVDAD 134
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANP 545
G N + Y L ++ + + V + + A L + A D P
Sbjct: 135 TGSNSVTTYRLNSNEYFSLDVQSGDDQSASAELVLLRSLDREKQAVLKLTLTALDGGKPP 194
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
S+ V ++ T P F + Y+ V N G+ V Q+ D E ++
Sbjct: 195 KTGSLSIDVNVLDANDNT-------PTFSKSLYKARVNENAPAGSPVIQLSATDLDEGDN 247
Query: 606 --VSYDLLH--GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVT 660
V Y + + F ++ SG +TV L + ++ A + + S +
Sbjct: 248 GRVVYSFVKRGNFNPADVFVIDAESGEVTVKAALDYETQSAFEVHVQARDKGFSPRSANS 307
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGT-----G 714
V VVDVND + A + ++ VKE++ G+A+ + T+ S T G
Sbjct: 308 KLLVEVVDVNDNAPEI---AVTSLVNPVKEDAEIGSAVALVTVTDKDSGKNGKTRTEIVG 364
Query: 715 NVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+V F L++N ++ ++ DG PLDREK Y +T+ A ++G + V
Sbjct: 365 SVPFKLLSNYKNY---YSLVVDG------PLDREKCSSYSITITAA-DEGSPPLSSTILV 414
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+++ D NDN P F ++ ENS +G I + I ATD D+ NA+ Y++
Sbjct: 415 IVHVADVNDNAPAFSSPEVNIYVKENSPVGALI---HTITATDPDKEENAIVTYSVMHGS 471
Query: 834 K------EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
+ + ++ TG + + S D E+ ++ + A D+G LSS + I I D
Sbjct: 472 RITQQKTWLISINSETGDIVSL-QSFDYEELKTFQFQVQATDSGVPPLSSTTVIQIHISD 530
Query: 886 ENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIP 945
NDN P F + V +H K N G TI+ + D+D+ EN
Sbjct: 531 VNDNAPLFKE----PVVNVH--VKENSPVGITILTIT-----TADLDR-------EENAK 572
Query: 946 IGTTIIK--LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY-FVINERHGHVI 1002
+ ++I N++ + S +N NS+ S D EVK + F + V
Sbjct: 573 VTYSLIDGLFNSISVRSAVN------INSDTGDITILQSFDYEEVKTFQFQVQATDSGV- 625
Query: 1003 VARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
P S +N+ LD NDN + ++H V ++ ++ E +
Sbjct: 626 ----PPLSSNVSVNVFILDE---NDNNP--AILAPYSEHGSVNSES-IPYSAEAGYF--- 672
Query: 1063 VLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTG 1100
+ K+ A D+D G NA L+Y + +P +L F + TG
Sbjct: 673 -VAKIRAVDSDSGYNALLSYHLSEPKGNNL-FRMGTSTG 709
Score = 96.3 bits (229), Expect = 6e-18
Identities = 134/560 (23%), Positives = 229/560 (40%), Gaps = 64/560 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E P G + A+D D+G N Y NS Y S D
Sbjct: 115 ISEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNEYFSLDVQSGDDQSAS---------A 165
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ RSL E + +L ++ALDGG ++S+ V V D ND+ P F K+ Y V
Sbjct: 166 ELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKARVN 225
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP--FEISPLTGVLSVNGELDRET 1112
E + ++ ATD D G N + Y F++ + + F I +G ++V LD ET
Sbjct: 226 ENAPAGSPVIQLSATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEVTVKAALDYET 285
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ + + V ARD G DVNDN+P+ A L+ +A+ S
Sbjct: 286 QSAFEVHVQARDKG-FSPRSANSKLLVEVVDVNDNAPEI-AVTSLVNPVKEDAEIGSAVA 343
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG-------NGNGLILYSLPQRKNQQ 1225
+V K +G+ K+ +N ++ + YS+ +
Sbjct: 344 LVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYYSLVVDGPLDREKCSSYSITITAADE 403
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTE 1283
G P LSST +++V VADV D + P F S + ++EN V A + ++ +
Sbjct: 404 --GSPPLSSTILVIVHVADVND-----NAPAFSSPEVNIYVKENSPVGALIHTITATDPD 456
Query: 1284 HYENFKMRYYILNENDTDIRRTFV--IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
EN + Y +++ + ++T++ I+ G + ++S D E T++ V+A
Sbjct: 457 KEENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSG-- 514
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA-IPTTAPFGYQ 1400
+ P++ + + + I DVNDN+P F P+V + +P G
Sbjct: 515 ------VPPLSSTTV---------IQIHISDVNDNAPLF---KEPVVNVHVKENSPVGIT 556
Query: 1401 VMQLKGAIGHHPTASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILNE- 1459
++ + A ++ + D L F +S+ + + DI I Y+ +
Sbjct: 557 ILTITTADLDREENAKVTYSLIDGL--FNSISVRSAVNINSDTGDITILQSFDYEEVKTF 614
Query: 1460 ----QAPRFAIDPVSGTVRV 1475
QA + P+S V V
Sbjct: 615 QFQVQATDSGVPPLSSNVSV 634
Score = 82.6 bits (195), Expect = 8e-14
Identities = 58/174 (33%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNG---SLFLEKELDLDAEHNLQANTFVLQV 276
A+D D G + Y L N + FSLD +G S E L + QA L +
Sbjct: 130 AVDADTGSNSVTTYRL---NSNEYFSLDVQSGDDQSASAELVLLRSLDREKQA-VLKLTL 185
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P KT +++ +LD NDN P F Y + EN P G V+Q+ ATD D+G
Sbjct: 186 TALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKARVNENAPAGSPVIQLSATDLDEG 245
Query: 337 ENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+NG Y +P F ID SG +TV+ LD E S+ + V A++
Sbjct: 246 DNGRVVYSFVKRGNFNPADVFVIDAESGEVTVK--AALDYETQSAFEVHVQARD 297
Score = 78.6 bits (185), Expect = 1e-12
Identities = 83/334 (24%), Positives = 150/334 (44%), Gaps = 30/334 (8%)
Query: 576 APYEFWVGSNVGIGTSVGQIRVNDAFEQNDV---SYDLLHGYEEGVPFAVEERSGVITVV 632
A F V V GT VG + + D+ + +++ GY + F ++G + V
Sbjct: 2 AQTSFSVSEEVDKGTVVGNLAKHLNVNIRDLHARNLNIVSGYSKKY-FEANSKTGDLVVN 60
Query: 633 DDLSRYNRPMYDFEAVALQENANLS---IVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
+ + R + L A LS ++ V + D+ND V L+ ++S I
Sbjct: 61 ERIDREELCPNTVKCT-LNLEAILSDPVVLHRIEVVISDLNDNAPVFLEKSYSLNI---- 115
Query: 690 ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD-DIAIAEDGTIFTQ----KPL 744
S + G+ F ++ G+ +V N + D+ +D + + + L
Sbjct: 116 --SEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNEYFSLDVQSGDDQSASAELVLLRSL 173
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
DREK+ V ++T+ A + G G + + + D NDN P F + Y+ + EN+ G+
Sbjct: 174 DREKQAVLKLTLTA-LDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKARVNENAPAGS 232
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGK----EMFDVDENTGVVKFIGDSLDREKKIM 860
+ + ATD DEG N +Y+ G ++F +D +G V + +LD E +
Sbjct: 233 PVIQ---LSATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEVT-VKAALDYETQSA 288
Query: 861 YKLSLVARDTG--GLSSEAELIIMIGDENDNKPE 892
+++ + ARD G S+ ++L++ + D NDN PE
Sbjct: 289 FEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPE 322
Score = 77.8 bits (183), Expect = 2e-12
Identities = 98/419 (23%), Positives = 175/419 (41%), Gaps = 35/419 (8%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V ++D NDN P ++L +K +A++G+ + V D D G+NG ++ +
Sbjct: 311 VEVVDVNDNAPEIAVTSLVN-PVKEDAEIGSAVALVTVTDKDSGKNGKTRTEIVGSVPFK 369
Query: 507 ITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ S +K N ++ V + P+ + +++ + A+D+ + P + V +V
Sbjct: 370 LLSNYK---NYYSL-VVDGPLDREKCSSYSITITAADEGSPPLSSTILVIVHVADVN--- 422
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG----YEEG 617
+ P F +V N +G + I D ++ + V+Y ++HG ++
Sbjct: 423 ----DNAPAFSSPEVNIYVKENSPVGALIHTITATDPDKEENAIVTYSVMHGSRITQQKT 478
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
++ +G I + + F+ A LS T +H+ DVND L
Sbjct: 479 WLISINSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSTTVIQIHISDVNDN-APL 537
Query: 677 LKGAHSPII-FHVKENS-AGAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAIA 733
K P++ HVKENS G I I ++ T ++ + N V + I
Sbjct: 538 FK---EPVVNVHVKENSPVGITILTITTADLDREENAKVTYSLIDGLFNSISVRSAVNIN 594
Query: 734 ED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
D G I + D E+ ++ V A + GV + V ++I DENDN P
Sbjct: 595 SDTGDITILQSFDYEEVKTFQFQVQAT-DSGVPPLSSNVSVNVFILDENDNNPAILAPYS 653
Query: 793 EGFIMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
E + + I + I+A D+D G NAL Y L +G +F + +TG ++
Sbjct: 654 EHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNALLSYHLSEPKGNNLFRMGTSTGEIR 712
Score = 70.1 bits (164), Expect = 4e-10
Identities = 88/334 (26%), Positives = 146/334 (43%), Gaps = 29/334 (8%)
Query: 43 LVDSDSPQNVVKFRLGCDFDEGDDLVRIGA---GLNQISAYLSVTVYIEDVNDNVPIFLD 99
++D++S + VK L + + V + A G + SA + V + DVNDN P
Sbjct: 267 VIDAESGEVTVKAALDYETQSAFE-VHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAV 325
Query: 100 TPYHVTVDELTPTGEKAFIFLIAPI-----GPSLT-IPLTVP-RGLTIFKDIRAFDRDKP 152
T V E G + + G + T I +VP + L+ +K+ + D P
Sbjct: 326 TSLVNPVKEDAEIGSAVALVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYYSLVVDGP 385
Query: 153 NTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKE 211
YSI ++ D+G L S+ +L++ V D + F + + +
Sbjct: 386 LDREKCSSYSITITAADEGSPPLSST---ILVIVHVADVNDNAPAFSSPEVNIYVKENSP 442
Query: 212 I-LFPEPIHAIDQDLGVGATLRYELISGN---DRK--LFSLDSVNGSLFLEKELDLDAEH 265
+ I A D D A + Y ++ G+ +K L S++S G + + D +
Sbjct: 443 VGALIHTITATDPDKEENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYE--- 499
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
+ TF QVQA+ P ++ ++I + D+NDN P F+ N+ + EN P G ++
Sbjct: 500 --ELKTFQFQVQATDSGVPPLSSTTVIQIHISDVNDNAPLFKEPVVNVHVKENSPVGITI 557
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGAF-SIDPRS 358
L + D D+ EN + TY L D G F SI RS
Sbjct: 558 LTITTADLDREENAKVTYSLID--GLFNSISVRS 589
Score = 62.5 bits (145), Expect = 9e-08
Identities = 67/243 (27%), Positives = 101/243 (41%), Gaps = 23/243 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++EV N A ++ + + E+ IG+ + + D DSG NG+ R E V
Sbjct: 310 LVEVVDVNDNAPEIAVTSLVNPVKEDAEIGSAVALVTVTDKDSGKNGKTRTEIVGSV--- 366
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
P KL ++ K Y+ + +V L E S + + I+A D G+ L+ I V V
Sbjct: 367 PFKLLSN---YKNYYSL-------VVDGPLDREKCSSYSITITAADEGSPPLSSTILVIV 416
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-----PSD 1088
V DVND+ P F N V+E ++ + ATD D +NA +TY +
Sbjct: 417 HVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDKEENAIVTYSVMHGSRITQQ 476
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
I+ TG + D E + V A D+G DVNDN+
Sbjct: 477 KTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSG-VPPLSSTTVIQIHISDVNDNA 535
Query: 1149 PKF 1151
P F
Sbjct: 536 PLF 538
Score = 61.3 bits (142), Expect = 2e-07
Identities = 43/127 (33%), Positives = 68/127 (53%), Gaps = 9/127 (7%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF--VLQVQASQLNNPLKTAQARV 292
++SG +K F +S G L + + +D + L NT L ++A L++P+ R+
Sbjct: 39 IVSGYSKKYFEANSKTGDLVVNERIDRE---ELCPNTVKCTLNLEAI-LSDPV--VLHRI 92
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF 352
E+ + DLNDN P F Y+++I E P G L +A D D G N TY+L+ + F
Sbjct: 93 EVVISDLNDNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNE-YF 151
Query: 353 SIDPRSG 359
S+D +SG
Sbjct: 152 SLDVQSG 158
Score = 54.0 bits (124), Expect = 3e-05
Identities = 53/224 (23%), Positives = 90/224 (40%), Gaps = 20/224 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV-INERH 998
+ EN P+G I + A D D N + Y + S+++ + K + + IN
Sbjct: 437 VKENSPVGALIHTITATDPDKEENAIVTYSV-----MHGSRIT----QQKTWLISINSET 487
Query: 999 GHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G ++ +S E F+ + A D G L+ +++ + DVND+ P+FK+ N +V
Sbjct: 488 GDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSTTVIQIHISDVNDNAPLFKEPVVNVHV 547
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-----FIQPSDTDLPFEISPLTGVLSVNGELD 1109
+E + + D D +NA +TY I+ TG +++ D
Sbjct: 548 KENSPVGITILTITTADLDREENAKVTYSLIDGLFNSISVRSAVNINSDTGDITILQSFD 607
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
E + V A D+G D NDN+P A
Sbjct: 608 YEEVKTFQFQVQATDSG-VPPLSSNVSVNVFILDENDNNPAILA 650
Score = 52.4 bits (120), Expect = 9e-05
Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 19/171 (11%)
Query: 218 IHAIDQDLGVGATLRYELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I D D A + Y LI G + R +++S G + + + D + + TF
Sbjct: 560 ITTADLDREENAKVTYSLIDGLFNSISVRSAVNINSDTGDITILQSFDYE-----EVKTF 614
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLPN----GFSVL 326
QVQA+ P ++ V + +LD NDN P + V E++P G+ V
Sbjct: 615 QFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVA 674
Query: 327 QVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWL-TVRNQTVLDREAH 374
++ A D D G N +Y L +PKG F + +G + T R + D ++H
Sbjct: 675 KIRAVDSDSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSH 725
Score = 50.0 bits (114), Expect = 5e-04
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 18/176 (10%)
Query: 989 KRYFVINERHGHVIVARSLPPES------EFRLNISALDGGNLNDNI---SVRVFVKDVN 1039
K+YF N + G ++V + E + LN+ A+ L+D + + V + D+N
Sbjct: 45 KKYFEANSKTGDLVVNERIDREELCPNTVKCTLNLEAI----LSDPVVLHRIEVVISDLN 100
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD---TDLPF-EI 1095
D+ PVF + Y+ N+ E T A DAD G N+ TY + ++ D+ +
Sbjct: 101 DNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNEYFSLDVQSGDD 160
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ L + LDRE + LT+ A D G D NDN+P F
Sbjct: 161 QSASAELVLLRSLDREKQAVLKLTLTALDGG-KPPKTGSLSIDVNVLDANDNTPTF 215
Score = 46.0 bits (104), Expect = 0.008
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V+V V +LD NDNNP + P ++ S+ +A+ G + K++AVD D G N
Sbjct: 628 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNA 687
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV 520
++ Y L + F++ +TG +
Sbjct: 688 LLSYHLSEPKGNNL---FRMGTSTGEI 711
Score = 41.5 bits (93), Expect = 0.17
Identities = 15/33 (45%), Positives = 23/33 (69%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK 115
+ V I D+NDN P+FL+ Y + + E +PTGE+
Sbjct: 92 IEVVISDLNDNAPVFLEKSYSLNISEWSPTGER 124
>UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1026
Score = 117 bits (282), Expect = 2e-24
Identities = 137/554 (24%), Positives = 232/554 (41%), Gaps = 34/554 (6%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+ Y M ++V V ++D ND+NPVF PS L E + A + I +A DPD G
Sbjct: 84 NVLYRKGGAMHLLSVRVEVMDLNDHNPVF-PSLLQEVEISETASLRMRIPLDRAADPDAG 142
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA-SDQPANPSERR 549
NG+ Y L + + + V + E + +L +E + NP +
Sbjct: 143 PNGLQTYTLSSNQHFALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSG 202
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
+ +VTI + + P F AP + N GT V +R D + +V
Sbjct: 203 STKIIVTI------LDSNDNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVE 256
Query: 608 YDLL-HG-YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATV 664
Y L H E F++ ++G +T+ L + +Y+ + A N + +
Sbjct: 257 YSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQI 316
Query: 665 HVVDVNDERG---VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ D+ND + SP+ V E + + + + NG V L
Sbjct: 317 KLQDINDNAPRIHITWTPPDSPVAT-VTEGAPNETFLALVMVSDADYGANGQVQVHILTG 375
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ I ++ I T LDREK+ Y +T++A+ + G S + I +T+++ DEN
Sbjct: 376 SGPFRLKQIH-GDNYMIVTNGTLDREKQMEYNLTLLAQ-DSGDPSLSCIKHLTVHVLDEN 433
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEGKEM 836
DNPP+F + Y + EN+ G ++A D D G + +++ G
Sbjct: 434 DNPPIFTKSHYRSILKENNTPGFHFL---TVEAHDVDLGLSGQVSFSIRESNELGTPTAF 490
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
F V ++G V + SLD E+ +Y + A D G ++S A +++ I D NDN P
Sbjct: 491 FSVHPSSGEVT-VQQSLDYEESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIY 549
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
+ + + +N G + E+ K A++ + N P G +
Sbjct: 550 EPLPKKGIAL-LNVPVNVDKGEIVTELGDK---AMEDNFHKHRNYSSLNKPEGFLATTIR 605
Query: 955 ALDLDSGLNGQIRY 968
A D DSGLNG++ +
Sbjct: 606 ASDPDSGLNGRLNF 619
Score = 89.8 bits (213), Expect = 5e-16
Identities = 124/489 (25%), Positives = 203/489 (41%), Gaps = 70/489 (14%)
Query: 680 AHSPIIFHV-KENSAGAAIGQIFHTNMSSIYGNG-TGNVR-FLIANQQDVTDDIAIAEDG 736
AH I + V +E G +G++ + + G TG++ F + + DG
Sbjct: 4 AHLTIQYRVWEEQPPGTRVGRL----LDDLRERGETGSLENFQVVQHGHALPVTVASRDG 59
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHATYEG 794
T+ T LDRE+ FN G ++ +++ +E D ND+ PVF E
Sbjct: 60 TVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHNPVFPSLLQEV 119
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
I E + + I +D +A D D G N L YTL + F +D V+ G +
Sbjct: 120 EISETASLRMRIPLD---RAADPDAGPNGLQTYTL--SSNQHFALD-----VRSFGGAKQ 169
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
E + +L R+ L + EL ++ D+ N P+ ++K+ + T L+
Sbjct: 170 AELVVTKELD---RE---LQASLELELIAWDKG-NPPKSG----STKIIV---TILDSND 215
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
I E P + + EN GT ++ L A D D G NG++ Y +
Sbjct: 216 NSPIFEEAPS------------VIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKH- 262
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNIS 1030
LEV+R F I+ + G + + L E + + ++I A D G + +
Sbjct: 263 ---------SPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHK 313
Query: 1031 VRVFVKDVNDHFPVFKKTWYN-----FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
+++ ++D+ND+ P TW V E L V +DAD+G N + I
Sbjct: 314 LQIKLQDINDNAPRIHITWTPPDSPVATVTEGAPNETFLALVMVSDADYGANGQVQVHIL 373
Query: 1086 PSDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
PF + + G ++ NG LDRE + +Y LT++A+D+G
Sbjct: 374 TGSG--PFRLKQIHGDNYMIVTNGTLDREKQMEYNLTLLAQDSG-DPSLSCIKHLTVHVL 430
Query: 1143 DVNDNSPKF 1151
D NDN P F
Sbjct: 431 DENDNPPIF 439
Score = 86.2 bits (204), Expect = 6e-15
Identities = 77/257 (29%), Positives = 114/257 (44%), Gaps = 16/257 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G Y L S N + S G+ E + + + LQA+ L++ A
Sbjct: 136 AADPDAGPNGLQTYTL-SSNQHFALDVRSFGGAKQAELVVTKELDRELQAS-LELELIAW 193
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
NP K+ ++ + +LD NDN P FE I + EN G VL + ATD DQG NG
Sbjct: 194 DKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANG 253
Query: 340 EFTYQLD-----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
E Y L + + FSI P++G LT+ Q LD E + + + A++ P+ +
Sbjct: 254 EVEYSLSKHSPLEVQRLFSIHPKTGALTL--QGPLDFEEKNVYEVDIQARDLGPNGI--- 308
Query: 395 ADSQRIAKWRRQPLETNAPLEKTTYVFPDK-VGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
S + + Q + NAP T+ PD V T TE +E ++ V V AN
Sbjct: 309 -PSHHKLQIKLQDINDNAPRIHITWTPPDSPVATVTEGAP--NETFLALVMVSDADYGAN 365
Query: 454 DNNPVFVPSNLYEFSMK 470
V + + F +K
Sbjct: 366 GQVQVHILTGSGPFRLK 382
Score = 71.7 bits (168), Expect = 1e-10
Identities = 71/263 (26%), Positives = 114/263 (43%), Gaps = 39/263 (14%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SE 1012
A D D+G NG Y +S + AL+V+ + + ++V + L E +
Sbjct: 136 AADPDAGPNGLQTYTLSSNQHF--------ALDVRSFG--GAKQAELVVTKELDRELQAS 185
Query: 1013 FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
L + A D GN + S ++ V D ND+ P+F++ + E ++ + AT
Sbjct: 186 LELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELAENTIRGTIVLNLRAT 245
Query: 1071 DADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
D D G N + Y + P + F I P TG L++ G LD E ++ Y + + ARD G
Sbjct: 246 DPDQGANGEVEYSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLG- 304
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE 1187
D+NDN+P+ + + W P++ PV AT+
Sbjct: 305 PNGIPSHHKLQIKLQDINDNAPRIH-----ITWTPPDS--------------PV--ATVT 343
Query: 1188 ENAPIGTTVAKVFANDTDFIGNG 1210
E AP T +A V +D D+ NG
Sbjct: 344 EGAPNETFLALVMVSDADYGANG 366
Score = 55.6 bits (128), Expect = 1e-05
Identities = 46/158 (29%), Positives = 72/158 (45%), Gaps = 14/158 (8%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL-EKELDLDAEHNLQANTFVLQVQASQ 280
D D G ++ +++G+ F L ++G ++ LD E ++ N +L A
Sbjct: 359 DADYGANGQVQVHILTGSGP--FRLKQIHGDNYMIVTNGTLDREKQMEYNLTLL---AQD 413
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+P + + + +LD NDN P F Y + EN GF L V A D D G +G+
Sbjct: 414 SGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQ 473
Query: 341 FTY------QLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
++ +L P FS+ P SG +TV Q LD E
Sbjct: 474 VSFSIRESNELGTPTAFFSVHPSSGEVTV--QQSLDYE 509
Score = 55.2 bits (127), Expect = 1e-05
Identities = 46/152 (30%), Positives = 62/152 (40%), Gaps = 7/152 (4%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
E N+ GG ++ +SVRV V D+NDH PVF + E R + A D
Sbjct: 80 ELAFNVLYRKGGAMH-LLSVRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAAD 138
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGV----LSVNGELDRETEDKYILTVVARDNGX 1127
D G N TY + S+ ++ G L V ELDRE + L ++A D G
Sbjct: 139 PDAGPNGLQTYTLS-SNQHFALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKG- 196
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
D NDNSP F ++E
Sbjct: 197 NPPKSGSTKIIVTILDSNDNSPIFEEAPSVIE 228
Score = 52.8 bits (121), Expect = 7e-05
Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 17/223 (7%)
Query: 936 PLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
P+ + E P T + + D D G NGQ++ + P +L + Y ++
Sbjct: 338 PVATVTEGAPNETFLALVMVSDADYGANGQVQVHILTGS--GPFRLKQ--IHGDNYMIVT 393
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+G + + + E+ L + A D G+ L+ + V V D ND+ P+F K+ Y
Sbjct: 394 --NGTLDREKQM----EYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSI 447
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-DTDLP---FEISPLTGVLSVNGELD 1109
++E V+A D D G + +++ I+ S + P F + P +G ++V LD
Sbjct: 448 LKENNTPGFHFLTVEAHDVDLGLSGQVSFSIRESNELGTPTAFFSVHPSSGEVTVQQSLD 507
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
E Y V A D G DVNDN P Y
Sbjct: 508 YEESRVYSFIVEAVDQG-YPPMTSIAAVLVEIQDVNDNYPIIY 549
Score = 42.7 bits (96), Expect = 0.075
Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 4/92 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G+ L + + GN +F LD +G + ++ L TF L ++
Sbjct: 604 IRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSGEFY----VNTTNATELIGRTFKLGIE 659
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
S + P+ + + +E+ ++ D+L D
Sbjct: 660 VSDMGTPILSTRTTLEVTFINFRDHLKNLSHD 691
Score = 42.3 bits (95), Expect = 0.099
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V +E++DLND+ P F + I E + A D D G NG TY L +
Sbjct: 98 VRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQ-H 156
Query: 352 FSIDPRSGWLTVRNQTV----LDREAHSSLRMKVYA-KETNPSVVGT 393
F++D RS + + V LDRE +SL +++ A + NP G+
Sbjct: 157 FALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGS 203
>UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75;
Eukaryota|Rep: Protocadherin1-alpha-av15-vCP - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 939
Score = 117 bits (282), Expect = 2e-24
Identities = 119/458 (25%), Positives = 203/458 (44%), Gaps = 34/458 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + + +LD NDN PVF+ +Y ++ N VGT I +V A D D GQNG+V+Y L
Sbjct: 228 MTIIIDVLDINDNAPVFI-KEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHD 286
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
N + F +NP TG + V E + + + ++ASD+ P S VTI++
Sbjct: 287 VNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKS---VTIKIA 343
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N+P I + + GT+V I V+D + ++ + E +PF
Sbjct: 344 -DVNDNEPQIE---VTSLSSTIPEDSKPGTTVALISVSDL--DSGINGRVTCSLSENIPF 397
Query: 621 AV----EERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGV 675
+ +E + + L R YD A LS V + TV + DVND
Sbjct: 398 QLMPSSQENTYSLVTTSALDRETIAHYDITLEAKDAGQPPLSSVKSVTVQISDVNDNSP- 456
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQDVTDDIA 731
+ + SP F+V EN+A +F + S V + I + T I
Sbjct: 457 --EFSSSPYAFYVMENNAPGK--SLFSVSASDKDTGENSAVSYQIWRDGGAENKFTSFIN 512
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH- 789
I +E+G I+ K D E ++ ++A + G S + V ++I D+NDN PV +
Sbjct: 513 INSENGEIYALKSFDFETSKTFQFHILAT-DSGSPSLSSNVTVNVFILDQNDNVPVILYP 571
Query: 790 ATYEGFIMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLFGEGK-EMFDVDENTGV 845
+ G +I + ++ ++A DAD G N +++L + +F +D TG
Sbjct: 572 VSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQ 631
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ + S + +KL ++ +D G +S A +++
Sbjct: 632 IRTL-RSFTETDEAQHKLVILVKDNGNVSLSATATVIV 668
Score = 100 bits (240), Expect = 3e-19
Identities = 118/510 (23%), Positives = 209/510 (40%), Gaps = 36/510 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N++ E + V V ++D ND+ P+F P + G A DPD G
Sbjct: 107 NLKIALENPLEIHYVTVDVIDVNDHAPMF-PEQEKRLEISETVLPGARFQLQAARDPDSG 165
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSE 547
N + Y L T I + V + + P+ + L + A D P
Sbjct: 166 SNSVQTYKLSHTEYFRIEIKDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKS 225
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND- 605
+ ++ + +++ + P F+ Y + N +GT++ ++ D E QN
Sbjct: 226 GKMTIIIDVLDI-------NDNAPVFIKEVYSVTLNENTPVGTTILRVNATDLDEGQNGV 278
Query: 606 VSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNA 662
V Y L H + + F V +G I V L + +Y+ + A + A L+ +
Sbjct: 279 VVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSV 338
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNM-SSIYGNGTGNVRFLIA 721
T+ + DVND + + S I +++ G + I +++ S I G T ++ I
Sbjct: 339 TIKIADVNDNEPQIEVTSLSSTI--PEDSKPGTTVALISVSDLDSGINGRVTCSLSENIP 396
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
Q + ++ T LDRE Y +T+ A+ + G + + VT+ I D N
Sbjct: 397 FQLMPSSQ---ENTYSLVTTSALDRETIAHYDITLEAK-DAGQPPLSSVKSVTVQISDVN 452
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KE 835
DN P F + Y ++MEN+ G + + A+D D G N+ Y ++ +G
Sbjct: 453 DNSPEFSSSPYAFYVMENNAPGKSLFS---VSASDKDTGENSAVSYQIWRDGGAENKFTS 509
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE- 892
+++ G + + S D E ++ ++A D+G LSS + + I D+NDN P
Sbjct: 510 FININSENGEI-YALKSFDFETSKTFQFHILATDSGSPSLSSNVTVNVFILDQNDNVPVI 568
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
+ N E N AG + +V+
Sbjct: 569 LYPVSANGSAEGVEEIPRNVNAGHLVTKVR 598
Score = 86.6 bits (205), Expect = 5e-15
Identities = 71/238 (29%), Positives = 111/238 (46%), Gaps = 29/238 (12%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ P+F+ + EN P+GTTI+++NA DLD G NG + Y +V KL
Sbjct: 235 LDINDNAPVFIKEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDV---NDKL 291
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKD 1037
++ F +N G ++V L E + + ++I A D G L + SV + + D
Sbjct: 292 -------RKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIAD 344
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND+ P + T + + E + + +D D G N +T + ++PF++ P
Sbjct: 345 VNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLDSGINGRVTCSL---SENIPFQLMP 401
Query: 1098 L----TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
T L LDRET Y +T+ A+D G DVNDNSP+F
Sbjct: 402 SSQENTYSLVTTSALDRETIAHYDITLEAKDAG-QPPLSSVKSVTVQISDVNDNSPEF 458
Score = 85.4 bits (202), Expect = 1e-14
Identities = 92/342 (26%), Positives = 154/342 (45%), Gaps = 32/342 (9%)
Query: 1014 RLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+L ++ALDGG + +++ + V D+ND+ PVF K Y+ + E + +V+ATD
Sbjct: 211 KLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPVGTTILRVNATD 270
Query: 1072 ADFGQNANLTYFIQPSDTD---LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D GQN + Y + D F ++P+TG + V G LD E +D Y + + A D G
Sbjct: 271 LDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKG-I 329
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE-------LSNHNFESVMMIPV 1181
DVNDN P+ L PE + +S + +S + V
Sbjct: 330 APLTTDKSVTIKIADVNDNEPQIEVTS--LSSTIPEDSKPGTTVALISVSDLDSGINGRV 387
Query: 1182 YKATIEENAP---IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
++ EN P + ++ ++ T + + Y + ++ G P LSS +
Sbjct: 388 -TCSLSENIPFQLMPSSQENTYSLVTTSALDRETIAHYDI--TLEAKDAGQPPLSSVKSV 444
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP---VELVSLNLTEHYENFKMRYYIL 1295
V ++DV D + P F S Y + EN NAP + VS + + EN + Y I
Sbjct: 445 TVQISDVND-----NSPEFSSSPYAFYVMEN-NAPGKSLFSVSASDKDTGENSAVSYQIW 498
Query: 1296 NENDTDIRRT-FV-IDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + + T F+ I+ NG +Y ++S D E T++ + A
Sbjct: 499 RDGGAENKFTSFININSENGEIYALKSFDFETSKTFQFHILA 540
Score = 83.4 bits (197), Expect = 4e-14
Identities = 126/544 (23%), Positives = 231/544 (42%), Gaps = 65/544 (11%)
Query: 620 FAVEERSGVITVVDDLSRYN-----RPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F+V + GV+ V L R N P +AL+ + VT V V+DVND
Sbjct: 77 FSVNQNDGVLYVKGKLDRENVCERSTPCLINLKIALENPLEIHYVT---VDVIDVND--- 130
Query: 675 VLLKGAHSPIIFHVK---ENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDI 730
H+P+ + E S G F + +G+ +V+ + +++ + +I
Sbjct: 131 ------HAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEI 184
Query: 731 AIA-EDGTI---FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
EDG + QKPLDRE ++ + A + G +G + I + D NDN PV
Sbjct: 185 KDRYEDGKVPVLILQKPLDREVTKSIKLQLTA-LDGGRPPKSGKMTIIIDVLDINDNAPV 243
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDEN 842
F Y + EN+ +GT I + ATD DEG N + +Y+L + +++F+V+
Sbjct: 244 FIKEVYSVTLNENTPVGTTILR---VNATDLDEGQNGVVVYSLGHDVNDKLRKLFNVNPV 300
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENS 900
TG + G LD E K +Y++ + A D G L+++ + I I D NDN+P QIE S
Sbjct: 301 TGEIVVTG-LLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEP---QIEVTS 356
Query: 901 KVRIHRETKLNGTAGFTI----IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
E GT I ++ + + + P L+P + +++ +AL
Sbjct: 357 LSSTIPEDSKPGTTVALISVSDLDSGINGRVTCSLSENIPFQLMPSSQENTYSLVTTSAL 416
Query: 957 DLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY-----FVINERHGHVIVARSLPPES 1011
D ++ + I E P S + + +++ + + ++ + P +S
Sbjct: 417 DRETIAHYDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKS 476
Query: 1012 EFRLNISALDGGNLNDNISVRV------------FVKDVNDHFPVFKKTWYNFNVEEAQY 1059
F ++ S D G N +S ++ F+ +++ ++ ++F + +
Sbjct: 477 LFSVSASDKDTGE-NSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKT-F 534
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG--ELDRETEDKYI 1117
+L D+ N + FI + ++P + P++ S G E+ R ++
Sbjct: 535 QFHILA-TDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHL 593
Query: 1118 LTVV 1121
+T V
Sbjct: 594 VTKV 597
Score = 70.5 bits (165), Expect = 3e-10
Identities = 43/138 (31%), Positives = 75/138 (54%), Gaps = 12/138 (8%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L L+K LD + +++ LQ+ A P K+ + + I++LD+NDN P F + Y+
Sbjct: 196 LILQKPLDREVTKSIK-----LQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYS 250
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQT 367
+++ EN P G ++L+V ATD D+G+NG Y L D + F+++P +G + V
Sbjct: 251 VTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTG-- 308
Query: 368 VLDREAHSSLRMKVYAKE 385
+LD E + + A +
Sbjct: 309 LLDFEVKDIYEIDIQASD 326
Score = 68.1 bits (159), Expect = 2e-09
Identities = 81/289 (28%), Positives = 121/289 (41%), Gaps = 41/289 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ GTT+ ++ DLDSG+NG++ + + P +L + E V
Sbjct: 361 IPEDSKPGTTVALISVSDLDSGINGRVTCSLSENI---PFQLMPSSQENTYSLVTTSALD 417
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+A + + + A D G L+ SV V + DVND+ P F + Y F V E
Sbjct: 418 RETIAH-------YDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMEN 470
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL------DRE 1111
+ L V A+D D G+N+ ++Y I D + + + S NGE+ D E
Sbjct: 471 NAPGKSLFSVSASDKDTGENSAVSYQIW-RDGGAENKFTSFININSENGEIYALKSFDFE 529
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
T + ++A D+G D NDN P +P + +N
Sbjct: 530 TSKTFQFHILATDSG-SPSLSSNVTVNVFILDQNDNVPVIL---------YPVS---ANG 576
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
+ E V IP N G V KV A D D IG NG +L+SL +
Sbjct: 577 SAEGVEEIP-------RNVNAGHLVTKVRAYDAD-IGY-NGWLLFSLQE 616
Score = 67.3 bits (157), Expect = 3e-09
Identities = 68/298 (22%), Positives = 119/298 (39%), Gaps = 21/298 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G S +++ + + D+NDN P+F+ Y VT++E TP G +
Sbjct: 214 LTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPVGTTILRVNATDLDE 273
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPN-----------SDVHYSIVSGNDDGHFALE 175
+ G + +R P T D++ + +D G L
Sbjct: 274 GQNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPL- 332
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASG-KRIHKEILFPEPIHAIDQDLGVGATLRYE 234
++ K V + K+ D + + + ++ ++S K I D D G+ +
Sbjct: 333 TTDKSVTI--KIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLDSGINGRVTCS 390
Query: 235 LISGNDRKLFSLDSVNG-SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
L +L N SL LD + + + + ++A P ++ V
Sbjct: 391 LSENIPFQLMPSSQENTYSLVTTSALDRETIAH-----YDITLEAKDAGQPPLSSVKSVT 445
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
+++ D+NDN PEF Y ++EN G S+ V A+DKD GEN +YQ+ GA
Sbjct: 446 VQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSASDKDTGENSAVSYQIWRDGGA 503
Score = 60.5 bits (140), Expect = 3e-07
Identities = 47/173 (27%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y L ++ RKLF+++ V G + + LD + + + + +
Sbjct: 266 VNATDLDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVK-----DIYEI 320
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+QAS T V I++ D+NDN P+ EV + +I E+ G +V + +D D
Sbjct: 321 DIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLD 380
Query: 335 QGENGEFTYQLDDPKGAFSIDPRS--GWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG T L + F + P S ++ + LDRE + + + AK+
Sbjct: 381 SGINGRVTCSLSE-NIPFQLMPSSQENTYSLVTTSALDRETIAHYDITLEAKD 432
Score = 59.3 bits (137), Expect = 8e-07
Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN G ++ ++A D D+G N + Y+ + + + IN
Sbjct: 465 FYVMENNAPGKSLFSVSASDKDTGENSAVSYQIWRD--------GGAENKFTSFININSE 516
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNF 1052
+G + +S E+ F+ +I A D G+ L+ N++V VF+ D ND+ PV N
Sbjct: 517 NGEIYALKSFDFETSKTFQFHILATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANG 576
Query: 1053 NVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 577 SAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLR 636
Query: 1107 ELDRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 637 SFTETDEAQHKLVILVKDNG 656
Score = 58.4 bits (135), Expect = 1e-06
Identities = 79/336 (23%), Positives = 131/336 (38%), Gaps = 37/336 (11%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG 125
D+ G+ ++ SVT+ I DVNDN P T T+ E + G + ++ +
Sbjct: 321 DIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLD 380
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKP----NTPNSD----VHYSI-VSGNDDGHFALES 176
+ +T I + ++ T D HY I + D G L S
Sbjct: 381 SGINGRVTCSLSENIPFQLMPSSQENTYSLVTTSALDRETIAHYDITLEAKDAGQPPLSS 440
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI 236
+ + V D + LF + A D+D G + + Y++
Sbjct: 441 VKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFS--VSASDKDTGENSAVSYQIW 498
Query: 237 --SGNDRKLFS---LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
G + K S ++S NG ++ K D + + TF + A+ +P ++
Sbjct: 499 RDGGAENKFTSFININSENGEIYALKSFDFET-----SKTFQFHILATDSGSPSLSSNVT 553
Query: 292 VEIELLDLNDNLPEFEVDFYNISI------VENLPN----GFSVLQVMATDKDQGENGEF 341
V + +LD NDN+P V Y +S VE +P G V +V A D D G NG
Sbjct: 554 VNVFILDQNDNVP---VILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWL 610
Query: 342 TYQLDD--PKGAFSIDPRSGWL-TVRNQTVLDREAH 374
+ L + F++D +G + T+R+ T D H
Sbjct: 611 LFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQH 646
Score = 48.8 bits (111), Expect = 0.001
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 56/374 (14%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V DVNDH P+F + + E A D D G N+ TY + ++
Sbjct: 121 VTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEY- 179
Query: 1091 LPFEISP-----LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
EI VL + LDRE L + A D G D+N
Sbjct: 180 FRIEIKDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGG-RPPKSGKMTIIIDVLDIN 238
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DN+P F + V + + + T P+GTT+ +V N TD
Sbjct: 239 DNAPVF---------------------IKEVYSVTLNENT-----PVGTTILRV--NATD 270
Query: 1206 FIGNGNGLILYSLPQRKNQQ-------NLGLPSLSSTAILMVTVADVPD-EVEMSDK--- 1254
NG+++YSL N + N + T +L V D+ + +++ SDK
Sbjct: 271 LDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIA 330
Query: 1255 PVFISRYYELEIEE-NVNAP-VELVSLNLT---EHYENFKMRYYILNENDTDIRRTFVID 1309
P+ + ++I + N N P +E+ SL+ T + + +++ D+ I
Sbjct: 331 PLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLDSGINGRVTCS 390
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM-IYPVAEDVLEGMTKYDVKVVV 1368
+ + +E +TY ++ + + + H I A+D + V V
Sbjct: 391 LSENIPFQLMPSSQE--NTYSLVTTSALDR--ETIAHYDITLEAKDAGQPPLSSVKSVTV 446
Query: 1369 RIKDVNDNSPKFTN 1382
+I DVNDNSP+F++
Sbjct: 447 QISDVNDNSPEFSS 460
Score = 48.4 bits (110), Expect = 0.002
Identities = 47/172 (27%), Positives = 85/172 (49%), Gaps = 14/172 (8%)
Query: 221 IDQDLGVGA-TLR---YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ +DLG+ TL+ + ++S + +FS++ +G L+++ +LD E+ + +T L
Sbjct: 50 VAKDLGIDPKTLKERGFRIVSTSGESMFSVNQNDGVLYVKGKLD--RENVCERSTPCLIN 107
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
L NPL+ V ++++D+ND+ P F + I E + G A D D G
Sbjct: 108 LKIALENPLEIHY--VTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSG 165
Query: 337 ENGEFTYQLDDPKGAFSIDPR----SGWLTVR-NQTVLDREAHSSLRMKVYA 383
N TY+L + F I+ + G + V Q LDRE S+++++ A
Sbjct: 166 SNSVQTYKLSHTE-YFRIEIKDRYEDGKVPVLILQKPLDREVTKSIKLQLTA 216
Score = 46.8 bits (106), Expect = 0.005
Identities = 36/110 (32%), Positives = 53/110 (48%), Gaps = 11/110 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF---VPSNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQN 492
L S V V V +LD NDN PV V +N ++ N G ++ KV+A D D+G N
Sbjct: 548 LSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYN 607
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASD 540
G +L+ LQ S ++ F ++ TG + S E +H L + D
Sbjct: 608 GWLLFSLQEVSEHSL---FALDRYTGQIRTLRSFTETDEAQHKLVILVKD 654
>UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12;
Amniota|Rep: Protocadherin-16 precursor - Homo sapiens
(Human)
Length = 3298
Score = 117 bits (282), Expect = 2e-24
Identities = 126/451 (27%), Positives = 199/451 (44%), Gaps = 33/451 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V L D NDN+P F P+ + N GT I ++A+DPD G N V + L
Sbjct: 880 VRVLLDDVNDNSPAF-PAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGG 938
Query: 505 LTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F ++P TG V + P H L +EA D + P + L VV +V G
Sbjct: 939 ----GAFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDV--G 992
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV--PF 620
T+G P F Y + S GT V Q++ A + ++Y L EG PF
Sbjct: 993 TRGLAPR---FNSPTYRVDLPSGTTAGTQVLQVQAQ-APDGGPITYHLA---AEGASSPF 1045
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTN-ATVHVVDVN-DERGVLL 677
+E +SG + V L R + +Y + +A+ A L T ATV V +N +E L
Sbjct: 1046 GLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRL 1105
Query: 678 KGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AED 735
+ P V EN G ++G++F T+ S G + + + + + I +
Sbjct: 1106 --SEDPTFLAVAENQPPGTSVGRVFATDRDS---GPNGRLTYSLQQLSEDSKAFRIHPQT 1160
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + T + LDRE++ Y++ V + + G + V + + D NDN P F A+
Sbjct: 1161 GEVTTLQTLDREQQSSYQLLVQVQ-DGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAG 1219
Query: 796 IMENSKIGTEIKMDNII---KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
++ + ++ +A D DEG N +YTL G G E+F + ++G +
Sbjct: 1220 GGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHSGEL-LTAAP 1278
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
L R ++ Y L+L A D G A L +++
Sbjct: 1279 LIRAERPHYVLTLSAHDQGSPPRSASLQLLV 1309
Score = 115 bits (277), Expect = 9e-24
Identities = 131/463 (28%), Positives = 199/463 (42%), Gaps = 32/463 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++VTLLD ND+ P F S + +S A G+ + +V A D D G NG V Y++ R +
Sbjct: 241 LDVTLLDINDHAPAFNQSRYHAVVSESLAP-GSPVLQVFASDADAGVNGAVTYEINRRQS 299
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
PF I+ +TG + + E R H L V+A D A+P A VT+ V R
Sbjct: 300 -EGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHP---ELGSAFVTVHV-RD 354
Query: 563 TKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N+P + F+ A V G V +I V+D + + ++ EG FA
Sbjct: 355 ANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEG-HFA 413
Query: 622 VEERSGVI---TVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
+ + VI V L R R Y+ A + L +HV DVND
Sbjct: 414 LSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFD 473
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGT-GNVRFLIANQQDVTDDIAIAED 735
+ + P E A+ F +++ GT G V + +A
Sbjct: 474 RQLYRP------EPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTS 527
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T LD E ++ V+A + G+ A V++ ++D NDN P F+ Y
Sbjct: 528 GIITTAASLDYELEPQPQLIVVAT-DGGLPPLASSATVSVALQDVNDNEPQFQRTFYNAS 586
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYT----LFGEGKEMFDVDENTGVVKFIGD 851
+ E ++ GT + ATDAD G L Y+ L G F +D ++G V
Sbjct: 587 LPEGTQPGTCFLQ---VTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDV-CTTR 642
Query: 852 SLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+LDR++ + ++ A D GGL S + + + DENDN P+F
Sbjct: 643 TLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPPQF 685
Score = 105 bits (253), Expect = 7e-21
Identities = 124/465 (26%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT---VIGKVKAVDPDLGQNGMV 495
L + V+V +T+ D ND+ P F S L + T + ++A D D G N +
Sbjct: 1940 LSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASI 1999
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLA 553
LY L T T ++ TG + VA SP+ G LF+ A+D P+ +
Sbjct: 2000 LYRLAGTPPPGTT----VDSYTGEIRVARSPVALGPRDRVLFIVATDL-GRPARSATGVI 2054
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLH 612
+V G +G P F A E + N GT + R A N ++Y +L
Sbjct: 2055 IV------GLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAGGTNGPITYSILS 2108
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G E+G F+++ +G ITV V E+ T T+ + D ND
Sbjct: 2109 GNEKGT-FSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAFTVLTLTLQDANDN 2167
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
L+ + + F + + Q+ ++ G+G G + + +A Q +
Sbjct: 2168 APRFLRPHY--VAFLPESRPLEGPLLQVEADDLDQ--GSG-GQISYSLAASQPARGLFHV 2222
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
GTI T LDRE R+ ++A ++G + G +T+ + D NDN P
Sbjct: 2223 DPTTGTITTTAILDREIWAETRLVLMAT-DRGSPALVGSATLTVMVIDTNDNRPTIPQP- 2280
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIG 850
+E + E++ +G+EI + D D G + Y L G ++ F V G V G
Sbjct: 2281 WELRVSEDALLGSEIAQ---VTGNDVDSGP--VLWYVLSPSGPQDPFSVGRYGGRVSLTG 2335
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
LD E+ Y+L L+A D G A L +++ D NDN P F+Q
Sbjct: 2336 P-LDFEQCDRYQLQLLAHD-GPHEGRANLTVLVEDVNDNAPAFSQ 2378
Score = 101 bits (241), Expect = 2e-19
Identities = 120/460 (26%), Positives = 198/460 (43%), Gaps = 33/460 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQR 501
+ V+V + D N++ P F L ++ N + G + +A D D G N V Y L R
Sbjct: 1420 LRVQVQVQDENEHAPAFARDPL-ALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLR 1478
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEV 559
+++ TG +S E AL VEA+D+PAN S RR + + V
Sbjct: 1479 QE--PPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFV 1536
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEG 617
T ++ D +P + + G + + R D E VSY L G +
Sbjct: 1537 T-----DENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASGGDG- 1590
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVDVNDERGVL 676
F + +G ++VV L R R + VA + T TV V DVNDE
Sbjct: 1591 -HFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTF 1649
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ +S ++ + N G ++ + T+ G V + + + + D + G
Sbjct: 1650 QQQEYSVLL--RENNPPGTSLLTLRATDPDV---GANGQVTYGGVSSESFSLD---PDTG 1701
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ T + LDRE+++ +TV A+ ++G V + +EDEND+ P F A +
Sbjct: 1702 VLTTLRALDREEQEEINLTVYAQ-DRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEV 1760
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDR 855
E G + + +++A+D D G N Y + G+ F +D +G + LDR
Sbjct: 1761 PE----GQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTM-RPLDR 1815
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
E + ++L + ARD G LS+ L + + D ND+ P F
Sbjct: 1816 EVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAF 1855
Score = 99 bits (238), Expect = 5e-19
Identities = 125/499 (25%), Positives = 206/499 (41%), Gaps = 39/499 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNL-----YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
V V +LD NDN+P F+ ++ + GT++ ++A DPD G+NG +LY L
Sbjct: 1197 VHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTL 1256
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTI 557
+ F ++P++G + A I R + L + A DQ + P L V +
Sbjct: 1257 TGPGS----ELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1312
Query: 558 EVTRGTKGNKPDIPDFMGA---PYEFWVGSNVGI--GTSVGQIRVNDAFEQNDVSYDLLH 612
R + PD+ + A P V + G+ G+ +G + + ++Y L+
Sbjct: 1313 PSARLAEP-PPDLAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVG 1371
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVND 671
G + FA++ SG + + L P + V + + V V D N+
Sbjct: 1372 GADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENE 1431
Query: 672 ERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDD 729
A P+ + EN GAA+ + S G G +VR+ + Q+
Sbjct: 1432 HAPAF---ARDPLALALPENPEPGAAL---YTFRASDADGPGPNSDVRYRLLRQEPPVPA 1485
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT--IYIEDENDNPPV 786
+ + A G + + LDRE + V A S +V+ +++ DENDN PV
Sbjct: 1486 LRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPV 1545
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
F + + E+ G + A D D G A Y L G F + +TG +
Sbjct: 1546 FASPSRVR-LPEDQPPGPAALH---VVARDPDLGEAARVSYRLASGGDGHFRLHSSTGAL 1601
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
+ LDRE++ + L++VA D G S+ L + + D ND P F Q E + +
Sbjct: 1602 SVVRP-LDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSV---L 1657
Query: 905 HRETKLNGTAGFTIIEVKP 923
RE GT+ T+ P
Sbjct: 1658 LRENNPPGTSLLTLRATDP 1676
Score = 96.7 bits (230), Expect = 4e-18
Identities = 120/467 (25%), Positives = 195/467 (41%), Gaps = 34/467 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V L D NDN P F Y S+ + GT +V A D D G G++ Y
Sbjct: 558 LASSATVSVALQDVNDNEPQF-QRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYS 616
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + + PF+I+ ++G V + + + F D + ++V ++
Sbjct: 617 LGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSF----DFTVTAVDGGGLKSMVYVK 672
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEE 616
V + + P P F Y + + GT+V ++R +D + +SY +L G
Sbjct: 673 VFLSDENDNP--PQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSP 730
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
+ F ++E+SG++TV L+R + E + ++ L +A VD++ G
Sbjct: 731 PL-FTLDEQSGLLTVAWPLARRANSVVQLE-IGAEDGGGLQAEPSAR---VDISIVPGTP 785
Query: 677 LKGAHSPI--IFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI- 732
+ +F V E+ A G ++G + N T L + D ++
Sbjct: 786 TPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVT-----LSLSGGDPRGLFSLD 840
Query: 733 AEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A G + T +PLDRE V + V A GV + +V + ++D NDN P F
Sbjct: 841 AVSGLLQTLRPLDRELLGPVLELEVRA--GSGVPPAFAVARVRVLLDDVNDNSPAFPAPE 898
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ N+ GT I ++A D D G N+ +TL G F VD TG V+ +
Sbjct: 899 DTVLLPPNTAPGTPI---YTLRALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHVRLM-R 954
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN--KPEFN 894
L ++L L ARD G +S L +++ D P FN
Sbjct: 955 PLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFN 1001
Score = 93.9 bits (223), Expect = 3e-17
Identities = 62/173 (35%), Positives = 90/173 (52%), Gaps = 11/173 (6%)
Query: 215 PEPIHAI--DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
P +H + D DLG A + Y L SG D F L S G+L + + LD + Q
Sbjct: 1562 PAALHVVARDPDLGEAARVSYRLASGGDGH-FRLHSSTGALSVVRPLDRE-----QRAEH 1615
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
VL V AS +P ++A + + + D+ND P F+ Y++ + EN P G S+L + ATD
Sbjct: 1616 VLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATD 1675
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G NG+ TY +FS+DP +G LT LDRE + + VYA++
Sbjct: 1676 PDVGANGQVTYG-GVSSESFSLDPDTGVLTTLR--ALDREEQEEINLTVYAQD 1725
Score = 92.3 bits (219), Expect = 9e-17
Identities = 116/464 (25%), Positives = 188/464 (40%), Gaps = 50/464 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ P G + + A D D G ++ Y S D +F ++ G
Sbjct: 1554 LPEDQPPGPAALHVVARDPDLGEAARVSYRLAS---------GGDG-----HFRLHSSTG 1599
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V R L E +E L + A D G+ + + + V V DVND P F++ Y+ +
Sbjct: 1600 ALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLR 1659
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E L + ATD D G N +TY S++ F + P TGVL+ LDRE +++
Sbjct: 1660 ENNPPGTSLLTLRATDPDVGANGQVTYGGVSSES---FSLDPDTGVLTTLRALDREEQEE 1716
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKHPEADELSNHN 1172
LTV A+D G D ND++P F + E+ E + P+ + +
Sbjct: 1717 INLTVYAQDRG-SPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQDPQTLTMLRAS 1775
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
V + I + P G V + + + + + + + R ++ G P+L
Sbjct: 1776 DPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPAL 1835
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY 1292
S+T +L VTV D D P F Y +E+ E+V P + L L H +
Sbjct: 1836 SATLLLTVTVLDANDHA-----PAFPVPAYSVEVPEDV--PAGTLLLQLQAHDPDAGANG 1888
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
++ F+++P +G L + DRE +Y V A
Sbjct: 1889 HVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSA----------------V 1932
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
+ G V V + ++DVND++P F PL +P P
Sbjct: 1933 DGAAAGPLSTTVSVTITVRDVNDHAPTFPTS--PLRLRLPRPGP 1974
Score = 90.6 bits (215), Expect = 3e-16
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 8/167 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+G L+Y ++ G+ F LD +G + LD + E F L+++
Sbjct: 1772 LRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTMRPLDREVEP-----AFQLRIE 1826
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P +A + + +LD ND+ P F V Y++ + E++P G +LQ+ A D D G
Sbjct: 1827 ARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGA 1886
Query: 338 NGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG TY L GAF ++P SG L R LDRE S V A
Sbjct: 1887 NGHVTYYLGAGTAGAFLLEPSSGEL--RTAAALDREQCPSYTFSVSA 1931
Score = 89.8 bits (213), Expect = 5e-16
Identities = 119/475 (25%), Positives = 208/475 (43%), Gaps = 45/475 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L+ + V ++D NDN P +P +E + +A +G+ I +V D D +G VL+
Sbjct: 2257 LVGSATLTVMVIDTNDNRPT-IPQP-WELRVSEDALLGSEIAQVTGNDVD---SGPVLWY 2311
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
+ S PF + G VS+ E R+ L + A D P E R +L V+
Sbjct: 2312 VLSPSGPQ--DPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHD---GPHEGRANLTVLV 2366
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGY 614
+V + P F + Y+ + + G+++ + D + +SY L
Sbjct: 2367 EDVN-------DNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASPA 2419
Query: 615 EEGVPFAVEERSGVI-TVVDDLSRYNRPMYDFEAVA-LQENANLSIVTNATVHVV--DVN 670
+ F+V+ +G + T+V ++ + + V +++ ATVHV D N
Sbjct: 2420 DG---FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQN 2476
Query: 671 DER-GVLLKGAHSPIIFHVKENS------AGAAIGQIFHTNMS-SIYGNGTGNVRFLIAN 722
D L + + S A A G H + SI G V L
Sbjct: 2477 DHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLEPR 2536
Query: 723 QQDVTDDIAIAED--GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ + G + +PLD E Y +TV A ++G + + VT+ + D
Sbjct: 2537 LAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAA-DRGQPPQSSVVPVTVTVLDV 2595
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDV 839
NDNPPVF A+Y + E++ +G E+ ++A+DAD G + L +T+ G+ +F++
Sbjct: 2596 NDNPPVFTRASYRVTVPEDTPVGAELLH---VEASDADPGPHGLVRFTVSSGDPSGLFEL 2652
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEF 893
DE++G ++ + +LD E + ++L + A D G + A + I + D ND+ P F
Sbjct: 2653 DESSGTLR-LAHALDCETQARHQLVVQAADPAGAHFALAPVTIEVQDVNDHGPAF 2706
Score = 89.0 bits (211), Expect = 9e-16
Identities = 108/450 (24%), Positives = 195/450 (43%), Gaps = 40/450 (8%)
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKI 513
+ P F P E +++ NA GT I +AV G NG + Y + + F I
Sbjct: 2063 ERGPRF-PRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSGNE---KGTFSI 2117
Query: 514 NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
P+TG ++V + L+ + + Q + +++ +T++ + P F
Sbjct: 2118 QPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAFTVLTLTLQDAND------NAPRF 2171
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYEEGVPFAVEERSGVITV 631
+ Y ++ + + + Q+ +D + + +SY L F V+ +G IT
Sbjct: 2172 LRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITT 2231
Query: 632 VDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDERGVLLKGAHSPIIFHVK 689
L R +A + + ++V +AT V V+D ND R + + P V
Sbjct: 2232 TAILDREIWAETRLVLMAT-DRGSPALVGSATLTVMVIDTNDNRPTIPQ----PWELRVS 2286
Query: 690 ENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDRE 747
E++ G+ I Q+ ++ S G V + + + D ++ G + PLD E
Sbjct: 2287 EDALLGSEIAQVTGNDVDS------GPVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFE 2340
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
+ D Y++ ++A + G G +T+ +ED NDN P F + Y+ ++E++ G+ I
Sbjct: 2341 QCDRYQLQLLA--HDGPHEGRA--NLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAIL 2396
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV-KFIGD-SLDREKKIMYKLSL 865
+ ATD D G N Y L + F VD N G + +G +L + + L
Sbjct: 2397 S---VSATDRDSGANGHISYHL-ASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVL 2452
Query: 866 VARDTG--GLSSEAELIIMIGDENDNKPEF 893
ARD G G ++ A + + + D+ND+ P F
Sbjct: 2453 EARDHGAPGRAARATVHVQLQDQNDHAPSF 2482
Score = 89.0 bits (211), Expect = 9e-16
Identities = 117/479 (24%), Positives = 197/479 (41%), Gaps = 55/479 (11%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+ V + D NDN P F S LY+ + + G+ I V A D D G NG + Y L +
Sbjct: 2361 NLTVLVEDVNDNAPAFSQS-LYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASPA 2419
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHA-----LFVEASDQPANPSERRYSLAVVTIE 558
+ F ++PN GT+ + G + +EA D A P R + A V ++
Sbjct: 2420 D-----GFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGA-PG--RAARATVHVQ 2471
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND---VSYDLLHGYE 615
+ + P F + Y V ++ G+++ + DA V Y ++ G
Sbjct: 2472 L----QDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISG-N 2526
Query: 616 EGVPFAVEERS--------------GVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVT 660
G F +E R G + +++ L + Y+ A S V
Sbjct: 2527 WGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVV 2586
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
TV V+DVND V + ++ + ++ GA ++ H S G VRF +
Sbjct: 2587 PVTVTVLDVNDNPPVFTRASYRVTV--PEDTPVGA---ELLHVEASDADPGPHGLVRFTV 2641
Query: 721 ANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
++ D + + E GT+ LD E + +++ V A G + + VTI ++D
Sbjct: 2642 SSG-DPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAG--AHFALAPVTIEVQD 2698
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-----GEGK 834
ND+ P F + EN GT + + A D D G Y+L EG+
Sbjct: 2699 VNDHGPAFPLNLLSTSVAENQPPGTLV---TTLHAIDGDAGAFGRLRYSLLEAGPGPEGR 2755
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
E F ++ +TG ++ D E ++L + A D G LS+ + +++ E++ P F
Sbjct: 2756 EAFALNSSTGELR-ARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYDPVF 2813
Score = 88.6 bits (210), Expect = 1e-15
Identities = 120/486 (24%), Positives = 194/486 (39%), Gaps = 51/486 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V + D ND+ P F P + + GT A D D G+ G Y L
Sbjct: 127 VEVTVRVADINDHAPAF-PQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSG- 184
Query: 503 SNLTITSPFKINPNTGTVSVAESPIL-----EGR--HALFVEASDQPANPSERRYSLAVV 555
T + P V E + E R + L +EA D + P + L V
Sbjct: 185 DGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVT 244
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHG 613
+++ P F + Y V ++ G+ V Q+ +DA V+Y++
Sbjct: 245 LLDIN-------DHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRR 297
Query: 614 YEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-ATVHVVDVND 671
EG PF+++ +G++ + L R +++ A A+ + + TVHV D ND
Sbjct: 298 QSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDAND 357
Query: 672 ERG----VLLKGAHSPIIFHVKENSAGAAI--------GQIFHTNMSSIYGNGTGNVRFL 719
+ + L SP + A G H N+S G G F
Sbjct: 358 NQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEG----HFA 413
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
++ Q V + +A + LDRE+RD Y + V A + G +++ D
Sbjct: 414 LSTQDSVIYLVCVA--------RRLDREERDAYNLRVTAT-DSGSPPLRAEAAFVLHVTD 464
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFD 838
NDN P F+ Y + + + + A D D+GTN Y+L G F
Sbjct: 465 VNDNAPAFDRQLYRPEPLPEVALPGSFVVR--VTARDPDQGTNGQVTYSLAPGAHTHWFS 522
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
+D +G++ SLD E + +L +VA D G L+S A + + + D NDN+P+F +
Sbjct: 523 IDPTSGIITTAA-SLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRT 581
Query: 897 EENSKV 902
N+ +
Sbjct: 582 FYNASL 587
Score = 87.8 bits (208), Expect = 2e-15
Identities = 115/477 (24%), Positives = 205/477 (42%), Gaps = 47/477 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F + +TL DANDN P F+ + F +S G ++ +V+A D D G G + Y L
Sbjct: 2153 AFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLL-QVEADDLDQGSGGQISYSL- 2210
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
++ F ++P TGT++ E L + A+D+ + +L V+ I+
Sbjct: 2211 -AASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVID 2269
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
T N+P IP P+E V + +G+ + Q+ ND + V + +L
Sbjct: 2270 ----TNDNRPTIPQ----PWELRVSEDALLGSEIAQVTGNDV-DSGPVLWYVLSPSGPQD 2320
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
PF+V G +++ L Y + +A + N TV V DVND +
Sbjct: 2321 PFSVGRYGGRVSLTGPLDFEQCDRYQLQLLA--HDGPHEGRANLTVLVEDVNDNAPAFSQ 2378
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ ++ ++ G+AI + T+ S G++ + +A+ D +GT+
Sbjct: 2379 SLYQVML--LEHTPPGSAILSVSATDRDS---GANGHISYHLASPADGFS--VDPNNGTL 2431
Query: 739 FT---QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
FT L + + + A + G A V + ++D+ND+ P F + Y
Sbjct: 2432 FTIVGTVALGHDGSGAVDVVLEAR-DHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVA 2490
Query: 796 IMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLF-GEGKEMFDVD-------ENTGV- 845
+ E+ G+ + ++ATDAD ++A Y++ G +F ++ E+ G
Sbjct: 2491 VTEDLPPGSTLL---TLEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPG 2547
Query: 846 VKFIG-----DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ +G + LD E Y L++ A D G SS + + + D NDN P F +
Sbjct: 2548 PRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTR 2604
Score = 82.6 bits (195), Expect = 8e-14
Identities = 135/605 (22%), Positives = 235/605 (38%), Gaps = 65/605 (10%)
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFL--IPENIPIGTTIIKLN 954
E + ++R+ + + G FT++ + ++ L P ++ +PE+ P+ ++++
Sbjct: 2135 EVSPRLRLVLQAESGGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVE 2194
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SE 1012
A DLD G GQI Y A + + F ++ G + L E +E
Sbjct: 2195 ADDLDQGSGGQISYSL------------AASQPARGLFHVDPTTGTITTTAILDREIWAE 2242
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
RL + A D G+ L + ++ V V D ND+ P + W V E + +V
Sbjct: 2243 TRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPW-ELRVSEDALLGSEIAQVTGN 2301
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G L Y + PS PF + G +S+ G LD E D+Y L ++A D
Sbjct: 2302 DVDSGPV--LWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG----P 2355
Query: 1131 XXXXXXXXXXXXDVNDNSPKF-YAFDELLEWKH------------PEADELSNHNFESVM 1177
DVNDN+P F + +++ +H + D +N + +
Sbjct: 2356 HEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL 2415
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAI 1237
P +++ N T+ A D G+G + L R + G P ++ A
Sbjct: 2416 ASPADGFSVDPNNGTLFTIVGTVALGHD----GSGAVDVVLEARDH----GAPGRAARAT 2467
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE---HYENFKMRYYI 1294
+ V + D D P F +Y + + E++ L++L T+ + + Y I
Sbjct: 2468 VHVQLQDQNDHA-----PSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSI 2522
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAED 1354
++ N R F ++PR P +V E + + + A D
Sbjct: 2523 ISGN---WGRVFQLEPRLAEAGESAGPGPR---ALGCLVLLEPLDFESLTQYNLTVAAAD 2576
Query: 1355 VLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGA---IGHH 1411
+ V V V + DVNDN P FT + + +P P G +++ ++ + G H
Sbjct: 2577 RGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRV--TVPEDTPVGAELLHVEASDADPGPH 2634
Query: 1412 PTASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSG 1471
TV + +F S L A D + + Q + FA+ PV+
Sbjct: 2635 GLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHFALAPVTI 2694
Query: 1472 TVRVV 1476
V+ V
Sbjct: 2695 EVQDV 2699
Score = 81.0 bits (191), Expect = 2e-13
Identities = 87/329 (26%), Positives = 137/329 (41%), Gaps = 19/329 (5%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPIG 125
VR G+G+ A V V ++DVNDN P F V + T G + L G
Sbjct: 865 VRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSG 924
Query: 126 PSLTIPLTVPRG----LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
+ + T+ G T+ +P P+ + + DG +SH
Sbjct: 925 VNSRVTFTLLAGGGGAFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSH--- 981
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIH--KEILFPEPIHAIDQDLGVGATLRYELISGN 239
LR V+ D G + + R+ + + G + Y L +
Sbjct: 982 FRLRVVVQ-DVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGGPITYHLAAEG 1040
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
F L+ +G L++ LD +A+ V+ V S+ +T A V + +L+
Sbjct: 1041 ASSPFGLEPQSGWLWVRAALDREAQELYILK--VMAVSGSKAELGQQTGTATVRVSILNQ 1098
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY---QLDDPKGAFSIDP 356
N++ P D +++ EN P G SV +V ATD+D G NG TY QL + AF I P
Sbjct: 1099 NEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHP 1158
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++G +T QT LDRE SS ++ V ++
Sbjct: 1159 QTGEVTTL-QT-LDREQQSSYQLLVQVQD 1185
Score = 79.8 bits (188), Expect = 5e-13
Identities = 117/433 (27%), Positives = 178/433 (41%), Gaps = 45/433 (10%)
Query: 919 IEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDS-GLNGQIRYEF-NSEVY 975
++V+ +N+ A + PL L +PEN G + A D D G N +RY E
Sbjct: 1424 VQVQDENEHAPAFAR-DPLALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPP 1482
Query: 976 IPPSKLSA--DALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRV 1033
+P +L A AL R +++ + + +A +S RV
Sbjct: 1483 VPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAA--------RVSARV 1534
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
FV D ND+ PVF + E Q V A D D G+ A ++Y + S D F
Sbjct: 1535 FVTDENDNAPVFASP-SRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLA-SGGDGHF 1592
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-- 1151
+ TG LSV LDRE +++LTVVA D+G DVND +P F
Sbjct: 1593 RLHSSTGALSVVRPLDREQRAEHVLTVVASDHG-SPPRSATQVLTVSVADVNDEAPTFQQ 1651
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI--GTTVAKVFANDTDFIGN 1209
+ LL +P S++ + + N + G ++ F+ D D
Sbjct: 1652 QEYSVLLRENNPPG--------TSLLTLRATDPDVGANGQVTYGGVSSESFSLDPD---T 1700
Query: 1210 GNGLILYSLPQRKNQQNLGLPSL-----SSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
G L +L R+ Q+ + L S + VTV V E E P F S + L
Sbjct: 1701 GVLTTLRAL-DREEQEEINLTVYAQDRGSPPQLTHVTVR-VAVEDENDHAPTFGSAHLSL 1758
Query: 1265 EIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
E+ E + P L L ++ N +++Y IL D D FV+D +G +R D
Sbjct: 1759 EVPEGQD-PQTLTMLRASDPDVGANGQLQYRIL---DGDPSGAFVLDLASGEFGTMRPLD 1814
Query: 1323 REVKDTYEVIVRA 1335
REV+ +++ + A
Sbjct: 1815 REVEPAFQLRIEA 1827
Score = 78.6 bits (185), Expect = 1e-12
Identities = 51/181 (28%), Positives = 88/181 (48%), Gaps = 10/181 (5%)
Query: 207 RIHKEILFPEPIHAID-QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH 265
R+ ++ L I + D+ G L Y L + FS+ G + L LD +
Sbjct: 2284 RVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFE--- 2340
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
Q + + LQ+ A + P + +A + + + D+NDN P F Y + ++E+ P G ++
Sbjct: 2341 --QCDRYQLQLLAH--DGPHE-GRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAI 2395
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAK 384
L V ATD+D G NG +Y L P FS+DP +G L T+ L + ++ + + A+
Sbjct: 2396 LSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEAR 2455
Query: 385 E 385
+
Sbjct: 2456 D 2456
Score = 76.2 bits (179), Expect = 7e-12
Identities = 109/467 (23%), Positives = 177/467 (37%), Gaps = 35/467 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V++ D ND P F Y ++ N GT + ++A DPD+G NG V Y
Sbjct: 1637 VSVADVNDEAPTFQQQE-YSVLLRENNPPGTSLLTLRATDPDVGANGQVTY------GGV 1689
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+ F ++P+TG ++ + E + L V A D+ + P L VT+ V +
Sbjct: 1690 SSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPP-----QLTHVTVRV--AVE 1742
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVPFAV 622
P F A V T + +R + D + Y +L G G F +
Sbjct: 1743 DENDHAPTFGSAHLSLEVPEGQDPQT-LTMLRASDPDVGANGQLQYRILDGDPSGA-FVL 1800
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ SG + L R P + A LS TV V+D ND A+
Sbjct: 1801 DLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAY 1860
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
S + ++ AG + Q+ + + G+V + + + G + T
Sbjct: 1861 SVEV--PEDVPAGTLLLQLQAHDPDA---GANGHVTYYL-GAGTAGAFLLEPSSGELRTA 1914
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE-GFIMENS 800
LDRE+ Y +V A + VTI + D ND+ P F +
Sbjct: 1915 AALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGP 1974
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD--SLDREKK 858
T ++A D D G NA +Y L G VD TG ++ +L +
Sbjct: 1975 SFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDR 2034
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQIEENSKVR 903
+++ +VA D G + A +I++G E + P F + + +R
Sbjct: 2035 VLF---IVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIR 2078
Score = 74.9 bits (176), Expect = 2e-11
Identities = 111/459 (24%), Positives = 183/459 (39%), Gaps = 34/459 (7%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN P F + A G+ + +V A DPD G NG V Y L ++ T
Sbjct: 464 DVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAH---THW 520
Query: 511 FKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F I+P +G ++ A S LE + L V A+D P +++V +V
Sbjct: 521 FSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNE----- 575
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ--NDVSYDLLHGYEEG--VPFAVEE 624
P F Y + GT Q+ DA +SY L G PF ++
Sbjct: 576 --PQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDA 633
Query: 625 RSGVITVVDDLSRYNRPM-YDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSP 683
SG + L R P +DF A+ + L + V + D ND ++
Sbjct: 634 HSGDVCTTRTLDRDQGPSSFDFTVTAV-DGGGLKSMVYVKVFLSDENDNPPQFYPREYAA 692
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV-TDDIAIAEDGTIFTQK 742
I ++ G A+ ++ + +G + L N + T D + G +
Sbjct: 693 SIS--AQSPPGTAVLRL-RAHDPDQGSHGRLSYHILAGNSPPLFTLD---EQSGLLTVAW 746
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PL R V ++ + AE + G + +V I I PP+FE Y + E+
Sbjct: 747 PLARRANSVVQLEIGAE-DGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAP 805
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
GT + I++A + + + G+ + +F +D +G+++ + LDRE +
Sbjct: 806 GTSV---GIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTL-RPLDRE-LLGPV 860
Query: 863 LSLVARDTGGLS---SEAELIIMIGDENDNKPEFNQIEE 898
L L R G+ + A + +++ D NDN P F E+
Sbjct: 861 LELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPED 899
Score = 74.5 bits (175), Expect = 2e-11
Identities = 86/302 (28%), Positives = 126/302 (41%), Gaps = 28/302 (9%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTV- 134
S+ + VTV + DVNDN P+F Y VTV E TP G + A GP + TV
Sbjct: 2583 SSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVS 2642
Query: 135 ---PRGLTIFKDIRAFDR--DKPNTPNSDVHYSIVSGNDDG--HFALESSHKPVLLLRKV 187
P GL + R + H +V D HFAL PV + +V
Sbjct: 2643 SGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHFALA----PVTI--EV 2696
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGND----RK 242
D + F L ++++ ++ +HAID D G LRY L+ R+
Sbjct: 2697 QDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGRE 2756
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
F+L+S G L + D EH +F L V A+ N +A V + + ++
Sbjct: 2757 AFALNSSTGEL--RARVPFDYEHT---ESFRLLVGAADAGN--LSASVTVSVLVTGEDEY 2809
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P F ++ + E G S+ V ATD+D G +G Y L F I+ +G L
Sbjct: 2810 DPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALY 2869
Query: 363 VR 364
+R
Sbjct: 2870 LR 2871
Score = 74.1 bits (174), Expect = 3e-11
Identities = 55/186 (29%), Positives = 90/186 (48%), Gaps = 16/186 (8%)
Query: 212 ILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT 271
I+ P +HA G + Y ++SGN++ FS+ G++ + LD E + +
Sbjct: 2087 IVSPRAVHAG----GTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLR- 2141
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
VLQ ++ A + + L D NDN P F Y + E+ P +LQV A
Sbjct: 2142 LVLQAESGGA-----FAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEAD 2196
Query: 332 DKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-N 387
D DQG G+ +Y L +G F +DP +G T+ +LDRE + R+ + A + +
Sbjct: 2197 DLDQGSGGQISYSLAASQPARGLFHVDPTTG--TITTTAILDREIWAETRLVLMATDRGS 2254
Query: 388 PSVVGT 393
P++VG+
Sbjct: 2255 PALVGS 2260
Score = 73.7 bits (173), Expect = 3e-11
Identities = 110/462 (23%), Positives = 174/462 (37%), Gaps = 30/462 (6%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ V V V + D ND+ P F ++L + T + ++A DPD+G NG + Y +
Sbjct: 1732 LTHVTVRVAVEDENDHAPTFGSAHL-SLEVPEGQDPQT-LTMLRASDPDVGANGQLQYRI 1789
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ GT+ + + E L +EA D P+ L VT+
Sbjct: 1790 LDGDPSGAFVLDLASGEFGTMRPLDREV-EPAFQLRIEARD-GGQPALSATLLLTVTV-- 1845
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEG 617
P F Y V +V GT + Q++ + DA V+Y L G
Sbjct: 1846 ----LDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYL--GAGTA 1899
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVNDERGV 675
F +E SG + L R P Y F A+ A LS + T+ V DVND
Sbjct: 1900 GAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPT 1959
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL--IANQQDVTDDIAIA 733
SP+ + + + + + + N L +A +
Sbjct: 1960 F---PTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSY 2016
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ P+ RD V + + S G+ + + ++ E + P F A+ E
Sbjct: 2017 TGEIRVARSPVALGPRDRVLFIVATDLGRPARSATGV--IIVGLQGEAERGPRFPRASSE 2074
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKF-IGD 851
I EN+ GT I + A GTN Y+ L G K F + +TG + +
Sbjct: 2075 ATIRENAPPGTPIVSPRAVHA----GGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAE 2130
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
LD E +L L A ++GG + L + + D NDN P F
Sbjct: 2131 GLDFEVSPRLRLVLQA-ESGGAFAFTVLTLTLQDANDNAPRF 2171
Score = 73.3 bits (172), Expect = 5e-11
Identities = 70/218 (32%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIAE-DGTIFTQKPLDR 746
+E AG IG I + G + F+ A + V D+AI E G + T + LDR
Sbjct: 53 EEQPAGTLIGDI---SAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDR 109
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E+RD YR T + GA + +VT+ + D ND+ P F A + E++ GT
Sbjct: 110 EQRDRYRFTAVTP------DGATV-EVTVRVADINDHAPAFPQARAALQVPEHTAFGTRY 162
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVD-----ENTGVVKF-IGDSLDREKKI 859
++ A DAD G Y L G+G E F ++ + T V + + LDRE +
Sbjct: 163 PLE---PARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRS 219
Query: 860 MYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
Y L L A D G ++A L + + D ND+ P FNQ
Sbjct: 220 HYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQ 257
Score = 73.3 bits (172), Expect = 5e-11
Identities = 66/221 (29%), Positives = 97/221 (43%), Gaps = 24/221 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE G+ ++++ A D D G NGQ+ Y + +F I+ G
Sbjct: 482 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHT-------------HWFSIDPTSG 528
Query: 1000 HVIVARSLPPESEFR--LNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A SL E E + L + A DGG L + +V V ++DVND+ P F++T+YN ++
Sbjct: 529 IITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLP 588
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQP---SDTDLPFEISPLTGVLSVNGELDRET 1112
E +V ATDAD G L+Y + S PF I +G + LDR+
Sbjct: 589 EGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQ 648
Query: 1113 -EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
+ TV A D G D NDN P+FY
Sbjct: 649 GPSSFDFTVTAVDGG---GLKSMVYVKVFLSDENDNPPQFY 686
Score = 72.9 bits (171), Expect = 6e-11
Identities = 90/308 (29%), Positives = 125/308 (40%), Gaps = 26/308 (8%)
Query: 83 VTVYIEDVNDNVP----IFLDTPYHVTVDELTPTGEK-AFIFLIAPI-GPSLTIPLTVPR 136
VTV++ D NDN P IFL V E P G+ A I + P G + +++
Sbjct: 348 VTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEG 407
Query: 137 GLTIF----KDIRAF---DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
G F +D + + + D + V+ D G L + VL + V D
Sbjct: 408 GEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVND 467
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
+A + QL + F + A D D G + Y L G FS+D
Sbjct: 468 -NAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPT 526
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G + LD + E Q L V A+ P + A V + L D+NDN P+F+
Sbjct: 527 SGIITTAASLDYELEPQPQ-----LIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRT 581
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-----FSIDPRSGWLTVR 364
FYN S+ E G LQV ATD D G G +Y L G+ F ID SG V
Sbjct: 582 FYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSG--DVC 639
Query: 365 NQTVLDRE 372
LDR+
Sbjct: 640 TTRTLDRD 647
Score = 72.1 bits (169), Expect = 1e-10
Identities = 91/359 (25%), Positives = 148/359 (41%), Gaps = 29/359 (8%)
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS--VGQIRVNDAFEQNDVSYDLLHG 613
T+EVT P F A V + GT + R DA Y L G
Sbjct: 126 TVEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGY-ALSG 184
Query: 614 YEEGVPFAVEERSGV-------ITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVH 665
G F +E R G + V +L R NR Y + A + V
Sbjct: 185 DGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVT 244
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
++D+ND + + ++ + + G+ + Q+F ++ + G V + I +Q
Sbjct: 245 LLDINDHAPAFNQSRYHAVVS--ESLAPGSPVLQVFASDADA---GVNGAVTYEINRRQS 299
Query: 726 VTDD-IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D +I A G + ++PLD E+R V+ + V A + G G VT+++ D NDN
Sbjct: 300 EGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQAR-DGGAHPELGSAFVTVHVRDANDN 358
Query: 784 PP----VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFD 838
P +F A + E + G + I +D D+G A +L G EG
Sbjct: 359 QPSMTVIFLSADGSPQVSEAAPPGQLVAR---ISVSDPDDGDFAHVNVSLEGGEGHFALS 415
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
++ + + LDRE++ Y L + A D+G L +EA ++ + D NDN P F++
Sbjct: 416 TQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDR 474
Score = 72.1 bits (169), Expect = 1e-10
Identities = 55/172 (31%), Positives = 87/172 (50%), Gaps = 8/172 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE-KELDLDAEHNLQANT-FVLQVQ 277
A D D G T Y L + F L++ G EL + E + + + ++LQ++
Sbjct: 167 ARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLE 226
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + AQA +++ LLD+ND+ P F Y+ + E+L G VLQV A+D D G
Sbjct: 227 AYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGV 286
Query: 338 NGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG TY+++ + G FSID +G L + + LD E + V A++
Sbjct: 287 NGAVTYEINRRQSEGDGPFSIDAHTGLLQL--ERPLDFEQRRVHELVVQARD 336
Score = 70.1 bits (164), Expect = 4e-10
Identities = 117/471 (24%), Positives = 189/471 (40%), Gaps = 36/471 (7%)
Query: 441 SFVNVEVTLLDANDNNP----VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+FV V V DANDN P +F+ ++ + A G ++ ++ DPD G V
Sbjct: 346 AFVTVHVR--DANDNQPSMTVIFLSADGSP-QVSEAAPPGQLVARISVSDPDDGDFAHVN 402
Query: 497 YDLQR-TSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
L+ + +++ + V VA E R A L V A+D + P A
Sbjct: 403 VSLEGGEGHFALSTQDSV---IYLVCVARRLDREERDAYNLRVTATDSGSPPLRAE---A 456
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+ VT N P + P + G R D V+Y L G
Sbjct: 457 AFVLHVT-DVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPG 515
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVND 671
F+++ SG+IT L P VA + + ++ATV V DVND
Sbjct: 516 AHTHW-FSIDPTSGIITTAASLDYELEPQPQLIVVAT-DGGLPPLASSATVSVALQDVND 573
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDVTDDI 730
+ ++ + + G Q+ T+ S +G + ++ + + I
Sbjct: 574 NEPQFQRTFYNASL--PEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRI 631
Query: 731 AIAEDGTIFTQKPLDREKR-DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
A G + T + LDR++ + TV A G+ S + V +++ DENDNPP F
Sbjct: 632 D-AHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKS---MVYVKVFLSDENDNPPQFYP 687
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY-TLFGEGKEMFDVDENTGVVKF 848
Y I S GT + ++A D D+G++ Y L G +F +DE +G++
Sbjct: 688 REYAASISAQSPPGTAVLR---LRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLT- 743
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEFNQIE 897
+ L R + +L + A D GGL +E A + I I P F Q++
Sbjct: 744 VAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQ 794
Score = 69.3 bits (162), Expect = 8e-10
Identities = 50/156 (32%), Positives = 69/156 (44%), Gaps = 6/156 (3%)
Query: 1001 VIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN-VE 1055
V VAR L E + L ++A D G+ L + + V DVND+ P F + Y +
Sbjct: 424 VCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLP 483
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + +V A D D G N +TY + P F I P +G+++ LD E E +
Sbjct: 484 EVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQ 543
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L VVA D G DVNDN P+F
Sbjct: 544 PQLIVVATDGG-LPPLASSATVSVALQDVNDNEPQF 578
Score = 68.9 bits (161), Expect = 1e-09
Identities = 72/261 (27%), Positives = 101/261 (38%), Gaps = 18/261 (6%)
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
E+ + R T T T+ V N A Q +PE+ GT A
Sbjct: 110 EQRDRYRFTAVTPDGATVEVTV-RVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPAR 168
Query: 957 DLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
D D+G G Y + E + ++ D V V E S
Sbjct: 169 DADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRE--------NRSH 220
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L + A DGG+ + V + D+NDH P F ++ Y+ V E+ + +V A+
Sbjct: 221 YMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFAS 280
Query: 1071 DADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
DAD G N +TY I + S+ D PF I TG+L + LD E + L V ARD G
Sbjct: 281 DADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGG-A 339
Query: 1129 XXXXXXXXXXXXXXDVNDNSP 1149
D NDN P
Sbjct: 340 HPELGSAFVTVHVRDANDNQP 360
Score = 67.7 bits (158), Expect = 2e-09
Identities = 79/288 (27%), Positives = 111/288 (38%), Gaps = 49/288 (17%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+P N GT I L ALD DSG+N ++ + L+ F ++
Sbjct: 902 LLPPNTAPGTPIYTLRALDPDSGVNSRVTFTL----------LAGGG----GAFTVDPTT 947
Query: 999 GHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDH--FPVFKKTWYNF 1052
GHV + R L P L + A DGG+ + +RV V+DV P F Y
Sbjct: 948 GHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRV 1007
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
++ + +V A D G +TY + PF + P +G L V LDRE
Sbjct: 1008 DLPSGTTAGTQVLQVQAQAPDGGP---ITYHLAAEGASSPFGLEPQSGWLWVRAALDREA 1064
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
++ YIL V+A +N N + LS
Sbjct: 1065 QELYILKVMAVSGSKAELGQQTGTATVRVSILNQNE---------------HSPRLSED- 1108
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
P + A + EN P GT+V +VFA D D NG + YSL Q
Sbjct: 1109 -------PTFLA-VAENQPPGTSVGRVFATDRD--SGPNGRLTYSLQQ 1146
Score = 67.3 bits (157), Expect = 3e-09
Identities = 107/467 (22%), Positives = 188/467 (40%), Gaps = 34/467 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V+V L D NDN P F P Y S+ + + GT + +++A DPD G +G + Y
Sbjct: 665 LKSMVYVKVFLSDENDNPPQFYPRE-YAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYH 723
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ ++ + F ++ +G ++VA + +E + + S A V I
Sbjct: 724 ILAGNSPPL---FTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPS-ARVDIS 779
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV-NDAFEQNDVSYDLLHGYEEG 617
+ GT P P F Y F V +V GTSVG ++ N V+ L G G
Sbjct: 780 IVPGT----PTPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRG 835
Query: 618 VPFAVEERSGVITVVDDLSR-YNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
+ F+++ SG++ + L R P+ + E A V V + DVND
Sbjct: 836 L-FSLDAVSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAF 894
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
A + + G I + + S N L T D G
Sbjct: 895 --PAPEDTVLLPPNTAPGTPIYTLRALDPDSGV-NSRVTFTLLAGGGGAFTVD---PTTG 948
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN--PPVFEHATYEG 794
+ +PL + + + A + G +++ + ++D P F TY
Sbjct: 949 HVRLMRPLGPSGGPAHELELEAR-DGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRV 1007
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDSL 853
+ + GT++ ++A D G Y L EG F ++ +G + ++ +L
Sbjct: 1008 DLPSGTTAGTQVLQ---VQAQAPDGGP---ITYHLAAEGASSPFGLEPQSGWL-WVRAAL 1060
Query: 854 DREKKIMYKLSLVA-----RDTGGLSSEAELIIMIGDENDNKPEFNQ 895
DRE + +Y L ++A + G + A + + I ++N++ P ++
Sbjct: 1061 DREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSE 1107
Score = 67.3 bits (157), Expect = 3e-09
Identities = 52/168 (30%), Positives = 75/168 (44%), Gaps = 9/168 (5%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDG-----GNLNDNISVRVFVKDVNDHFPV 1044
F + + G + V +L E++ + L + A+ G G +VRV + + N+H P
Sbjct: 1045 FGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPR 1104
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISPLTGVLS 1103
+ V E Q +G+V ATD D G N LTY +Q S+ F I P TG ++
Sbjct: 1105 LSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVT 1164
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE + Y L V +D G D+NDNSP F
Sbjct: 1165 TLQTLDREQQSSYQLLVQVQDGG-SPPRSTTGTVHVAVLDLNDNSPTF 1211
Score = 66.9 bits (156), Expect = 4e-09
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 8/218 (3%)
Query: 940 IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ E++P G+T++ L A D D S + + Y S + +L E R
Sbjct: 2491 VTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRA 2550
Query: 999 -GHVIVARSLPPES--EFRLNISALDGGNLNDN--ISVRVFVKDVNDHFPVFKKTWYNFN 1053
G +++ L ES ++ L ++A D G + + V V V DVND+ PVF + Y
Sbjct: 2551 LGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVT 2610
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E L V+A+DAD G + + + + D FE+ +G L + LD ET+
Sbjct: 2611 VPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQ 2670
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ L V A D DVND+ P F
Sbjct: 2671 ARHQLVVQAAD--PAGAHFALAPVTIEVQDVNDHGPAF 2706
Score = 66.9 bits (156), Expect = 4e-09
Identities = 55/182 (30%), Positives = 81/182 (44%), Gaps = 20/182 (10%)
Query: 930 DVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DV+ GP F + EN P GT + L+A+D D+G G++RY +
Sbjct: 2698 DVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLE---------A 2748
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVND 1040
E + F +N G + E FRL + A D GNL+ +++V V V ++
Sbjct: 2749 GPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDE 2808
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG 1100
+ PVF ++F V E LG V ATD D G + + Y + S F I+ TG
Sbjct: 2809 YDPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTG 2866
Query: 1101 VL 1102
L
Sbjct: 2867 AL 2868
Score = 66.1 bits (154), Expect = 7e-09
Identities = 57/174 (32%), Positives = 83/174 (47%), Gaps = 14/174 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G +R+ + SG+ LF LD +G+L L LD + + Q L VQ
Sbjct: 2624 VEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQ-----LVVQ 2678
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ A A V IE+ D+ND+ P F ++ + S+ EN P G V + A D D G
Sbjct: 2679 AADPAGA-HFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGA 2737
Query: 338 NGEFTYQL----DDPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G Y L P+G AF+++ +G L R + D E S R+ V A +
Sbjct: 2738 FGRLRYSLLEAGPGPEGREAFALNSSTGEL--RARVPFDYEHTESFRLLVGAAD 2789
Score = 65.3 bits (152), Expect = 1e-08
Identities = 51/190 (26%), Positives = 82/190 (43%), Gaps = 13/190 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE GT +++ A D DSG G + Y + + S F I+ G
Sbjct: 587 LPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSP----------PFRIDAHSG 636
Query: 1000 HVIVARSLPPE---SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
V R+L + S F ++A+DGG L + V+VF+ D ND+ P F Y ++
Sbjct: 637 DVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPPQFYPREYAASISA 696
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ ++ A D D G + L+Y I ++ F + +G+L+V L R
Sbjct: 697 QSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLTVAWPLARRANSVV 756
Query: 1117 ILTVVARDNG 1126
L + A D G
Sbjct: 757 QLEIGAEDGG 766
Score = 65.3 bits (152), Expect = 1e-08
Identities = 44/127 (34%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
LD E Q N L V A+ P +++ V + +LD+NDN P F Y +++ E+ P
Sbjct: 2560 LDFESLTQYN---LTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTP 2616
Query: 321 NGFSVLQVMATDKDQGENG--EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLR 378
G +L V A+D D G +G FT DP G F +D SG T+R LD E + +
Sbjct: 2617 VGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSG--TLRLAHALDCETQARHQ 2674
Query: 379 MKVYAKE 385
+ V A +
Sbjct: 2675 LVVQAAD 2681
Score = 64.9 bits (151), Expect = 2e-08
Identities = 117/491 (23%), Positives = 195/491 (39%), Gaps = 69/491 (14%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA----LEVKRYFVI 994
++ E++ G+ ++++ A D D+G+NG + YE N S DA L+++R
Sbjct: 263 VVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDF 322
Query: 995 NERHGHVIVARSLPPESEFRLNISALDGGNLND--NISVRVFVKDVNDHFP----VFKKT 1048
+R H +V + A DGG + + V V V+D ND+ P +F
Sbjct: 323 EQRRVHELV-------------VQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSA 369
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP-LTGVLSVNGE 1107
+ V EA +++ ++ +D D G A++ ++ + + ++ V
Sbjct: 370 DGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARR 429
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE D Y L V A D+G DVNDN+P AFD L P +
Sbjct: 430 LDREERDAYNLRVTATDSG-SPPLRAEAAFVLHVTDVNDNAP---AFDRQLYRPEPLPEV 485
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLIL------YSL-PQ 1220
+F V+ + N + ++A I +G+I Y L PQ
Sbjct: 486 ALPGSF--VVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQ 543
Query: 1221 RK---NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV 1277
+ + GLP L+S+A + V + DV D ++P F +Y + E +
Sbjct: 544 PQLIVVATDGGLPPLASSATVSVALQDVND-----NEPQFQRTFYNASLPEGTQPGTCFL 598
Query: 1278 SLNLTEHYEN-FKMRYYILNEN-DTDIRRTFVIDPRNGTLYLVRSPDREV-KDTYEVIVR 1334
+ T+ F + Y L + F ID +G + R+ DR+ +++ V
Sbjct: 599 QVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVT 658
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTT 1394
A V G K V V V + D NDN P+F R +I
Sbjct: 659 A-------------------VDGGGLKSMVYVKVFLSDENDNPPQFY--PREYAASISAQ 697
Query: 1395 APFGYQVMQLK 1405
+P G V++L+
Sbjct: 698 SPPGTAVLRLR 708
Score = 64.9 bits (151), Expect = 2e-08
Identities = 50/179 (27%), Positives = 75/179 (41%), Gaps = 13/179 (7%)
Query: 218 IHAIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D+D G L Y L D K F + G + + LD + Q +++ L V
Sbjct: 1127 VFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDRE-----QQSSYQLLV 1181
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEF------EVDFYNISIVENLPNGFSVLQVMA 330
Q +P ++ V + +LDLNDN P F I + + +P G V + A
Sbjct: 1182 QVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQA 1241
Query: 331 TDKDQGENGEFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D D+GENG Y L P FS+ P SG L + H L + + + + P
Sbjct: 1242 KDPDEGENGTILYTLTGPGSELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPP 1300
Score = 64.9 bits (151), Expect = 2e-08
Identities = 95/382 (24%), Positives = 158/382 (41%), Gaps = 41/382 (10%)
Query: 992 FVINERHGHVIVARSLPPES--EFR-LNISALDGGNLNDNI-SVRVFVKDVNDHFPVFKK 1047
F ++ G + +AR L E+ +R L + A G + V+V V+D N+H P F +
Sbjct: 1379 FALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFAR 1438
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADF-GQNANLTYFIQPSDTDLP-FEISPLTGVLSVN 1105
+ E L A+DAD G N+++ Y + + +P + TG LS
Sbjct: 1439 DPLALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAP 1498
Query: 1106 GELDRETEDKYILTVVARDN--GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
LDRET +L V A D D NDN+P F + + + P
Sbjct: 1499 RGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASPSRV---RLP 1555
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRK 1222
E D+ + + + + E A + +A D F + + G + P +
Sbjct: 1556 E-DQPPG---PAALHVVARDPDLGEAARVSYRLAS--GGDGHFRLHSSTGALSVVRPLDR 1609
Query: 1223 NQQ----------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
Q+ + G P S+T +L V+VADV DE P F + Y + + EN
Sbjct: 1610 EQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEA-----PTFQQQEYSVLLRENNPP 1664
Query: 1273 PVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
L++L T+ N ++ Y ++ +F +DP G L +R+ DRE ++
Sbjct: 1665 GTSLLTLRATDPDVGANGQVTYGGVSS------ESFSLDPDTGVLTTLRALDREEQEEIN 1718
Query: 1331 VIVRAERQKYSRELPHMIYPVA 1352
+ V A+ + +L H+ VA
Sbjct: 1719 LTVYAQDRGSPPQLTHVTVRVA 1740
Score = 64.9 bits (151), Expect = 2e-08
Identities = 74/319 (23%), Positives = 132/319 (41%), Gaps = 27/319 (8%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA---PIGPSLTIPLTV 134
+A +S V++ D NDN P+F +P V + E P G A + ++A +G + + +
Sbjct: 1527 AARVSARVFVTDENDNAPVFA-SPSRVRLPEDQPPGPAA-LHVVARDPDLGEAARVSYRL 1584
Query: 135 PRG----LTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
G + A +P + H V +D G ++ + + V D
Sbjct: 1585 ASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVND 1644
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV 249
++ + ++ L + A D D+G + Y +S FSLD
Sbjct: 1645 EAPTFQQQEYSVLLRENNPPGTSLLT--LRATDPDVGANGQVTYGGVSSES---FSLDPD 1699
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
G L + LD + + + L V A +P + V + + D ND+ P F
Sbjct: 1700 TGVLTTLRALDREEQEEIN-----LTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSA 1754
Query: 310 FYNISIVENL-PNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
++ + E P ++L+ A+D D G NG+ Y++ DP GAF +D SG
Sbjct: 1755 HLSLEVPEGQDPQTLTMLR--ASDPDVGANGQLQYRILDGDPSGAFVLDLASG--EFGTM 1810
Query: 367 TVLDREAHSSLRMKVYAKE 385
LDRE + ++++ A++
Sbjct: 1811 RPLDREVEPAFQLRIEARD 1829
Score = 63.3 bits (147), Expect = 5e-08
Identities = 84/326 (25%), Positives = 131/326 (40%), Gaps = 23/326 (7%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSL 128
G +SA L +TV + D ND+ P F Y V V E P G A +
Sbjct: 1831 GQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHV 1890
Query: 129 TIPLTV-PRGLTIFK----DIR-AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
T L G + + ++R A D+ P+ S V G G L ++ +
Sbjct: 1891 TYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAG--PLSTTVSVTI 1948
Query: 183 LLRKVLDYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+R V D+ +L + G L + A D+D G A++ Y L +G
Sbjct: 1949 TVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRL-AGTP 2007
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
++DS G + + + + L VL + A+ L P ++A + + L
Sbjct: 2008 PPGTTVDSYTGEIRVAR-----SPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEA 2062
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRS 358
+ P F +I EN P G ++ A G NG TY + + KG FSI P +
Sbjct: 2063 ERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSGNEKGTFSIQPST 2121
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAK 384
G +TVR+ LD E LR+ + A+
Sbjct: 2122 GAITVRSAEGLDFEVSPRLRLVLQAE 2147
Score = 62.9 bits (146), Expect = 7e-08
Identities = 58/202 (28%), Positives = 94/202 (46%), Gaps = 24/202 (11%)
Query: 936 PLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
P FL + EN P GT++ ++ A D DSG NG++ Y +LS D+ + F I
Sbjct: 1109 PTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSL--------QQLSEDS----KAFRI 1156
Query: 995 NERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKT-- 1048
+ + G V ++L E S ++L + DGG+ + +V V V D+ND+ P F +
Sbjct: 1157 HPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASG 1216
Query: 1049 ----WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
V + ++ + A D D G+N + Y + ++L F + P +G L
Sbjct: 1217 AAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSEL-FSLHPHSGELLT 1275
Query: 1105 NGELDRETEDKYILTVVARDNG 1126
L R Y+LT+ A D G
Sbjct: 1276 AAPLIRAERPHYVLTLSAHDQG 1297
Score = 61.7 bits (143), Expect = 2e-07
Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D GV + + + L++G F++D G + L + L L+++
Sbjct: 916 LRALDPDSGVNSRVTFTLLAGGGGA-FTVDPTTGHVRLMRPLGPSG-----GPAHELELE 969
Query: 278 ASQLNNPLKTAQARVEIELLDLNDN--LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A +P +T+ R+ + + D+ P F Y + + G VLQV A D
Sbjct: 970 ARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPD- 1028
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
G TY L + F ++P+SGWL VR LDREA +KV A + + +G
Sbjct: 1029 --GGPITYHLAAEGASSPFGLEPQSGWLWVR--AALDREAQELYILKVMAVSGSKAELG 1083
Score = 60.9 bits (141), Expect = 3e-07
Identities = 45/132 (34%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A + L G+ R LFSLD+V+G L + LD + L L+V+A P A
Sbjct: 822 APVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRE----LLGPVLELEVRAGS-GVPPAFA 876
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDD 347
ARV + L D+NDN P F + + N G + + A D D G N T+ L
Sbjct: 877 VARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAG 936
Query: 348 PKGAFSIDPRSG 359
GAF++DP +G
Sbjct: 937 GGGAFTVDPTTG 948
Score = 60.1 bits (139), Expect = 5e-07
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y L S D FS+D NG+LF A VL+
Sbjct: 2398 VSATDRDSGANGHISYHLASPADG--FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLE-- 2453
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A P + A+A V ++L D ND+ P F + Y +++ E+LP G ++L + ATD D
Sbjct: 2454 ARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDAD 2510
Score = 59.3 bits (137), Expect = 8e-07
Identities = 53/171 (30%), Positives = 85/171 (49%), Gaps = 13/171 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A + GVGA L Y L+ G D + F+LD+ +G L+L + LD +A +A L V+A
Sbjct: 1355 AAPEPAGVGA-LTYTLVGGADPEGTFALDAASGRLYLARPLDFEAGPPWRA----LTVRA 1409
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGE 337
RV++++ D N++ P F D +++ EN G ++ A+D D G
Sbjct: 1410 EGPGGA-GARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGP 1468
Query: 338 NGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + Y+L + P A +D R+G L+ LDRE +L + V A +
Sbjct: 1469 NSDVRYRLLRQEPPVPALRLDARTGALSAPRG--LDRETTPALLLLVEATD 1517
Score = 58.8 bits (136), Expect = 1e-06
Identities = 53/173 (30%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Query: 218 IHAIDQDLGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G L Y L +G + F +D+ +G + + LD D ++F
Sbjct: 600 VTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQG----PSSFDF 655
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A LK+ V++ L D NDN P+F Y SI P G +VL++ A D D
Sbjct: 656 TVTAVD-GGGLKS-MVYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPD 713
Query: 335 QGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
QG +G +Y + + F++D +SG LTV L R A+S +++++ A++
Sbjct: 714 QGSHGRLSYHILAGNSPPLFTLDEQSGLLTV--AWPLARRANSVVQLEIGAED 764
Score = 58.8 bits (136), Expect = 1e-06
Identities = 44/152 (28%), Positives = 70/152 (46%), Gaps = 23/152 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++P GT +++L A D D+G NG + Y Y+ A F++ G
Sbjct: 1864 VPEDVPAGTLLLQLQAHDPDAGANGHVTY------YLGAGTAGA--------FLLEPSSG 1909
Query: 1000 HVIVARSLPPES--EFRLNISALDG---GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ A +L E + ++SA+DG G L+ +SV + V+DVNDH P F + +
Sbjct: 1910 ELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRL 1969
Query: 1055 EEA----QYTRRVLGKVDATDADFGQNANLTY 1082
L + A D D G NA++ Y
Sbjct: 1970 PRPGPSFSTPTLALATLRAEDRDAGANASILY 2001
Score = 58.0 bits (134), Expect = 2e-06
Identities = 60/220 (27%), Positives = 97/220 (44%), Gaps = 27/220 (12%)
Query: 921 VKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
V P LDV+ P+F +PE+ P+G ++ + A D D G +G +R+ +S
Sbjct: 2585 VVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSG 2644
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGNLNDNIS- 1030
PS L F ++E G + +A +L E++ R L + A D + ++
Sbjct: 2645 ---DPSGL----------FELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHFALAP 2691
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--- 1087
V + V+DVNDH P F + +V E Q ++ + A D D G L Y + +
Sbjct: 2692 VTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPG 2751
Query: 1088 -DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+ F ++ TG L D E + + L V A D G
Sbjct: 2752 PEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAG 2791
Score = 57.2 bits (132), Expect = 3e-06
Identities = 87/318 (27%), Positives = 128/318 (40%), Gaps = 22/318 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--- 123
+V GL +++ +V+V ++DVNDN P F T Y+ ++ E T G F+ + A
Sbjct: 548 VVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGT-CFLQVTATDAD 606
Query: 124 IGPSLTIPLTVPRGLTIFKD----IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
GP + ++ GL I A D T D S D A++
Sbjct: 607 SGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQG-PSSFDFTVTAVDGGGL 665
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELI 236
++ KV D D Q I + + A D D G L Y ++
Sbjct: 666 KSMVYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHIL 725
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+GN LF+LD +G L + L A +Q L++ A ARV+I +
Sbjct: 726 AGNSPPLFTLDEQSGLLTVAWPLARRANSVVQ-----LEIGAEDGGGLQAEPSARVDISI 780
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSI 354
+ P FE Y S+ E++ G SV V A + G T L DP+G FS+
Sbjct: 781 VPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSL 839
Query: 355 DPRSGWLTVRNQTVLDRE 372
D SG L + LDRE
Sbjct: 840 DAVSGLL--QTLRPLDRE 855
Score = 56.0 bits (129), Expect = 7e-06
Identities = 61/213 (28%), Positives = 89/213 (41%), Gaps = 19/213 (8%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
P GT +++L A D D G +G++ Y + PP F ++E+ G + VA
Sbjct: 699 PPGTAVLRLRAHDPDQGSHGRLSYHILAG-NSPP------------LFTLDEQSGLLTVA 745
Query: 1005 RSLP--PESEFRLNISALDGGNLNDNISVRVFVKDV--NDHFPVFKKTWYNFNVEEAQYT 1060
L S +L I A DGG L S RV + V P+F++ Y F+V E
Sbjct: 746 WPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAP 805
Query: 1061 RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
+G V A + G+ A +T + D F + ++G+L LDRE +L +
Sbjct: 806 GTSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGP-VLEL 863
Query: 1121 VARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
R DVNDNSP F A
Sbjct: 864 EVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPA 896
Score = 54.4 bits (125), Expect = 2e-05
Identities = 70/275 (25%), Positives = 104/275 (37%), Gaps = 25/275 (9%)
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
+F Q + + + G A T++ V+ N A Q ++ E+ P G+ I+
Sbjct: 2338 DFEQCDRYQLQLLAHDGPHEGRANLTVL-VEDVNDNAPAFSQSLYQVMLLEHTPPGSAIL 2396
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
++A D DSG NG I Y S P S D + ++ G V +
Sbjct: 2397 SVSATDRDSGANGHISYHLAS----PADGFSVDPNNGTLFTIV----GTVALGHDGSGAV 2448
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+ L +V V ++D NDH P F + Y V E L ++ATD
Sbjct: 2449 DVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATD 2508
Query: 1072 ADFGQ-NANLTYFIQPSDTDLPFEISP--------------LTGVLSVNGELDRETEDKY 1116
AD + +A + Y I + F++ P G L + LD E+ +Y
Sbjct: 2509 ADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQY 2568
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LTV A D G DVNDN P F
Sbjct: 2569 NLTVAAADRG-QPPQSSVVPVTVTVLDVNDNPPVF 2602
Score = 53.2 bits (122), Expect = 5e-05
Identities = 47/176 (26%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK--LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D GV + YE+ FS+D+ G L LE+ LD + Q L
Sbjct: 277 VFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFE-----QRRVHELV 331
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS----IVENLPNGFSVLQVMAT 331
VQA + A V + + D NDN P V F + + E P G V ++ +
Sbjct: 332 VQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVS 391
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKET 386
D D G+ L+ +G F++ + + V LDRE + ++V A ++
Sbjct: 392 DPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDS 447
Score = 51.2 bits (117), Expect = 2e-04
Identities = 94/424 (22%), Positives = 156/424 (36%), Gaps = 33/424 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V L D ND+ P F S+ Y ++ + G+ + ++A D D G D S
Sbjct: 2468 VHVQLQDQNDHAPSFTLSH-YRVAVTEDLPPGSTLLTLEATDAD-GSRSHAAVDYSIISG 2525
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPAN-PSERRYSLAVVT------- 556
F++ P + P G AL +P + S +Y+L V
Sbjct: 2526 -NWGRVFQLEPRLAEAGESAGP---GPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPP 2581
Query: 557 ----IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
+ VT + P F A Y V + +G + + +DA V + +
Sbjct: 2582 QSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTV 2641
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
G G+ F ++E SG + + L + + A + T+ V DVN
Sbjct: 2642 SSGDPSGL-FELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHFALAPVTIEVQDVN 2700
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDD 729
D S V EN + H G L A + +
Sbjct: 2701 DHGPAFPLNLLST---SVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREA 2757
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
A+ + G + + P D E + +R+ V A + G +S + V + EDE D PVF
Sbjct: 2758 FALNSSTGELRARVPFDYEHTESFRLLVGAA-DAGNLSASVTVSVLVTGEDEYD--PVFL 2814
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ + E ++ G + ++ATD D G + L +Y+L F +++ TG +
Sbjct: 2815 APAFHFQVPEGARRGHSL---GHVQATDEDGGADGLVLYSL-ATSSPYFGINQTTGALYL 2870
Query: 849 IGDS 852
DS
Sbjct: 2871 RVDS 2874
Score = 43.6 bits (98), Expect = 0.043
Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 7/143 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G G + Y L + R LF +D G++ LD + + A T ++ +
Sbjct: 2193 VEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDRE----IWAETRLV-L 2247
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ +P A + + ++D NDN P + + + E+ G + QV D D G
Sbjct: 2248 MATDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGNDVDSG 2306
Query: 337 ENGEFTYQLDDPKGAFSIDPRSG 359
+ P+ FS+ G
Sbjct: 2307 PVLWYVLSPSGPQDPFSVGRYGG 2329
Score = 41.9 bits (94), Expect = 0.13
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V V + ++ +PVF+ + + F + A+ G +G V+A D D G +G+VLY
Sbjct: 2793 LSASVTVSVLVTGEDEYDPVFL-APAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYS 2851
Query: 499 LQRTSNLTITSPFKINPNTGTV 520
L +S F IN TG +
Sbjct: 2852 LATSSPY-----FGINQTTGAL 2868
Score = 41.1 bits (92), Expect = 0.23
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 7/162 (4%)
Query: 226 GVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
G + +RY L+ LD+ G+L + LD + L A+
Sbjct: 1467 GPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRR 1526
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
ARV + D NDN P F + + E+ P G + L V+A D D GE +Y+
Sbjct: 1527 AARVSARVFVT--DENDNAPVFASPS-RVRLPEDQPPGPAALHVVARDPDLGEAARVSYR 1583
Query: 345 L-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
L G F + +G L+V LDRE + + V A +
Sbjct: 1584 LASGGDGHFRLHSSTGALSVVRP--LDREQRAEHVLTVVASD 1623
Score = 36.3 bits (80), Expect = 6.5
Identities = 16/32 (50%), Positives = 21/32 (65%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
++TV +EDVNDN P F + Y V + E TP G
Sbjct: 2361 NLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPG 2392
Score = 35.9 bits (79), Expect = 8.6
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 820 GTNALFMYTLFG-EGKEM---FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
GT A MY + EG + +DE++GVV+ LDRE++ Y+ + V D +
Sbjct: 71 GTAAPLMYFISAQEGSGVGTDLAIDEHSGVVR-TARVLDREQRDRYRFTAVTPD----GA 125
Query: 876 EAELIIMIGDENDNKPEFNQIEENSKVRIH 905
E+ + + D ND+ P F Q +V H
Sbjct: 126 TVEVTVRVADINDHAPAFPQARAALQVPEH 155
>UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Danio
rerio|Rep: Protocadherin2-gamma-v12-sCP1 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 955
Score = 117 bits (281), Expect = 3e-24
Identities = 116/472 (24%), Positives = 208/472 (44%), Gaps = 42/472 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
M + V + D NDN P F + ++F + +A VG KA DPD+G N + Y L
Sbjct: 110 MELYTITVEITDINDNAPNFQKRD-FKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSL 168
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASD--QPANPSERRYSLAV 554
+ T + + + + + + + ++ L +EA D P + +AV
Sbjct: 169 KPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAV 228
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
+ I + P FM Y+ G+ + + D E ++V+Y +
Sbjct: 229 LDIN---------DNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISD 279
Query: 613 GYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
+ + F V E++G + +++ Y + + + ++ LS + V+DVN
Sbjct: 280 TMDSVMADMFLVNEQTGEL-ILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVN 338
Query: 671 DERGVL--LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
D + L +HS V E S + I N+ + +G V+ +++ +
Sbjct: 339 DNSPSINILSSSHS-----VSEGSKFGTV--IAMLNVDDLDSGASGQVQCVMSEEIPFVI 391
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ ++ T++ LDRE+ Y ++VI ++GV S + +T+ I D NDNPPVF+
Sbjct: 392 KSQSSNFFSLQTEQELDRERETEYNISVICS-DEGVPSLSSSVSLTVQISDVNDNPPVFK 450
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY-----TLFGEGKEMF-DVDEN 842
+ YE F+MEN+ G I +KA+DAD NA Y T+ G + V +
Sbjct: 451 KSNYEAFVMENNTPGLSI---FTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPD 507
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+G++ + S D E + + A+D G LSS + + + D+NDN P+
Sbjct: 508 SGLITAV-RSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQ 558
Score = 97.9 bits (233), Expect = 2e-18
Identities = 144/565 (25%), Positives = 230/565 (40%), Gaps = 80/565 (14%)
Query: 916 FTI-IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
+TI +E+ N A + + F I E+ +G + A D D G N Y
Sbjct: 113 YTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLK--- 169
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNIS 1030
P K LE++ ++ +I+ ++L E S F L + A DGG+ L+ +
Sbjct: 170 --PTDKFR---LELQSQ-ADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQ 223
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-DT 1089
+ + V D+ND+ PVF + Y E +L V ATD D G N+ +TY+I + D+
Sbjct: 224 IHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDS 283
Query: 1090 DLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
+ F ++ TG L +NG D E Y LT+ A+D G DVNDN
Sbjct: 284 VMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQG---GLSNACKVIIDVLDVNDN 340
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI 1207
SP +L H ++ F +V I + ++ G V V + + F+
Sbjct: 341 SPSI----NILSSSHSVSE---GSKFGTV--IAMLNVDDLDSGASG-QVQCVMSEEIPFV 390
Query: 1208 GNGNGLILYSLP-------QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSD 1253
+SL +R+ + N+ G+PSLSS+ L V ++DV D +
Sbjct: 391 IKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVND-----N 445
Query: 1254 KPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNE---NDTDIRRTFVID 1309
PVF YE + EN + + ++ ++ N R YIL + + + +
Sbjct: 446 PPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVH 505
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVR 1369
P +G + VRS D E + V+ A+D +V V V
Sbjct: 506 PDSGLITAVRSFDYETLKDFHFRVK-----------------AQDGGSPPLSSNVTVKVT 548
Query: 1370 IKDVNDNSPK----FTNGNRPLVTAIPTTAPFGYQVMQLKGA---IGHHPTASRTVRADT 1422
++D NDN+P+ G + +P A GY V ++ G + S ++
Sbjct: 549 VQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAP 608
Query: 1423 DELVFFERLSLNG--LTSPQATDSD 1445
D +F L NG T Q TD D
Sbjct: 609 DRALFEVGLQ-NGEIRTVRQVTDKD 632
Score = 95.5 bits (227), Expect = 1e-17
Identities = 109/472 (23%), Positives = 194/472 (41%), Gaps = 35/472 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L V + + +LD NDN PVF+ Y+ + A G+++ V A D D G N V
Sbjct: 215 DPVLSGTVQIHIAVLDINDNAPVFMQKE-YKATATEEAPKGSILTVVSATDTDEGSNSEV 273
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLA 553
Y + T + + F +N TG + + E + L + A DQ + + +
Sbjct: 274 TYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIID 333
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V+ + N P I + + + + GS GT + + V+D + S +
Sbjct: 334 VLDV------NDNSPSI-NILSSSHSVSEGSK--FGTVIAMLNVDDL--DSGASGQVQCV 382
Query: 614 YEEGVPFAVEERSG---VITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDV 669
E +PF ++ +S + +L R Y+ + E +LS + TV + DV
Sbjct: 383 MSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDV 442
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ----D 725
ND V K + F ++ N+ G + IF S N V +++ +
Sbjct: 443 NDNPPVFKKSNYE--AFVMENNTPGLS---IFTVKASDADWNQNARVSYILEDSTVSGVS 497
Query: 726 VTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
V+ +++ D G I + D E + V A+ + G + V + ++D+NDN
Sbjct: 498 VSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQ-DGGSPPLSSNVTVKVTVQDQNDNA 556
Query: 785 P--VFEHATYEGFIMENSKIGTEI-KMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVD 840
P ++ T + E ++ + + A D D G NA Y L + +F+V
Sbjct: 557 PQVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVG 616
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
G ++ + D++ + KL++V D G S A + I + D+ PE
Sbjct: 617 LQNGEIRTVRQVTDKD-AVKQKLTVVVEDNGQPSRSAVVSINVA-VADSFPE 666
Score = 87.8 bits (208), Expect = 2e-15
Identities = 74/249 (29%), Positives = 115/249 (46%), Gaps = 20/249 (8%)
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH----TNMSSIYG-NGTGNVR 717
TV + D+ND K I A +G+ F TN Y T R
Sbjct: 116 TVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFR 175
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ +Q D + ++ + QK LDRE + + + + A F+ G +G Q+ I +
Sbjct: 176 LELQSQADGSKNVEM------ILQKALDREMQSSFTLLLEA-FDGGDPVLSGTVQIHIAV 228
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY----TLFGEG 833
D NDN PVF Y+ E + G+ + ++ ATD DEG+N+ Y T+
Sbjct: 229 LDINDNAPVFMQKEYKATATEEAPKGSIL---TVVSATDTDEGSNSEVTYYISDTMDSVM 285
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+MF V+E TG + + D EK Y+L++ A+D GGLS+ ++II + D NDN P
Sbjct: 286 ADMFLVNEQTGEL-ILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSI 344
Query: 894 NQIEENSKV 902
N + + V
Sbjct: 345 NILSSSHSV 353
Score = 73.3 bits (172), Expect = 5e-11
Identities = 119/527 (22%), Positives = 212/527 (40%), Gaps = 48/527 (9%)
Query: 458 VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ-RTSNLTITSPFKINPN 516
V++ +S+ G+++G + DLG + L + R + T ++N N
Sbjct: 20 VYIARGQVSYSIPEEMAKGSMVGNIAQ---DLGLDLQRLKSGKARIFSRDSTEYIELNRN 76
Query: 517 TGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGA 576
TG + + E E A + + L +T+E+T + P+F
Sbjct: 77 TGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEIT----DINDNAPNFQKR 132
Query: 577 PYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY--EEGVPFAVEERS---GVITV 631
++F + + +G + + AF+ DV + L Y + F +E +S G V
Sbjct: 133 DFKFEISESAMVGA---RFMLGKAFDP-DVGTNSLQSYSLKPTDKFRLELQSQADGSKNV 188
Query: 632 VDDLSR-YNRPMYDFEAVALQENANLSIVTNATVH----VVDVNDERGVLLKGAHSPIIF 686
L + +R M + L+ V + TV V+D+ND V ++ +
Sbjct: 189 EMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATA- 247
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTDDIAIAED--GTIFTQKP 743
+E G+ + + T+ V + I++ D V D+ + + G +
Sbjct: 248 -TEEAPKGSILTVVSATDTDE---GSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGH 303
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
D EK Y +T+ A+ ++G +S A +V I + D NDN P + + E SK G
Sbjct: 304 FDYEKVSHYELTIHAK-DQGGLSNA--CKVIIDVLDVNDNSPSINILSSSHSVSEGSKFG 360
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
T I M N+ D D G + + E + + LDRE++ Y +
Sbjct: 361 TVIAMLNV---DDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNI 417
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
S++ D G LSS L + I D NDN P F + + V N T G +I V
Sbjct: 418 SVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFV------MENNTPGLSIFTV 471
Query: 922 KPKNKFALDVDQLGPL-FLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
K + D +Q + +++ ++ G ++ ++ DSGL +R
Sbjct: 472 KASD---ADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVR 515
Score = 70.9 bits (166), Expect = 2e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + Y L + +L +GS +E L + +Q++ F L ++A
Sbjct: 153 AFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSS-FTLLLEAF 211
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P+ + ++ I +LD+NDN P F Y + E P G + V ATD D+G N
Sbjct: 212 DGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNS 271
Query: 340 EFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
E TY + D + F ++ ++G L + D E S + ++AK+
Sbjct: 272 EVTYYISDTMDSVMADMFLVNEQTGELILNGH--FDYEKVSHYELTIHAKD 320
Score = 66.9 bits (156), Expect = 4e-09
Identities = 93/428 (21%), Positives = 172/428 (40%), Gaps = 39/428 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S + + + + D+NDN P+F+ Y T E P G + +T
Sbjct: 218 LSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYI 277
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDD----GHFALESSHKPVLLL----RKVL 188
T+ D D N ++ I++G+ D H+ L K L + ++
Sbjct: 278 SDTM--DSVMADMFLVNEQTGEL---ILNGHFDYEKVSHYELTIHAKDQGGLSNACKVII 332
Query: 189 DY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAID-QDLGVGATLRYELISGNDRKLFSL 246
D D D + I++S + + F I ++ DL GA+ + + + + F +
Sbjct: 333 DVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIP-FVI 391
Query: 247 DSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
S + + F L+ E +LD E + N V+ S P ++ + +++ D+NDN P
Sbjct: 392 KSQSSNFFSLQTEQELDRERETEYNISVI---CSDEGVPSLSSSVSLTVQISDVNDNPPV 448
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-------KGAFSIDPRS 358
F+ Y ++EN G S+ V A+D D +N +Y L+D S+ P S
Sbjct: 449 FKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDS 508
Query: 359 GWLT-VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKT 417
G +T VR+ D E +V A++ + S K Q NAP
Sbjct: 509 GLITAVRS---FDYETLKDFHFRVKAQDGGSPPL----SSNVTVKVTVQDQNDNAP---- 557
Query: 418 TYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT 477
++P + GT + ++ +V +D + ++ L + ++ +VG
Sbjct: 558 QVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGL 617
Query: 478 VIGKVKAV 485
G+++ V
Sbjct: 618 QNGEIRTV 625
Score = 64.1 bits (149), Expect = 3e-08
Identities = 57/199 (28%), Positives = 89/199 (44%), Gaps = 19/199 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F++ N P G +I + A D D N ++ Y + + V Y ++
Sbjct: 457 FVMENNTP-GLSIFTVKASDADWNQNARVSYILEDS--------TVSGVSVSSYVSVHPD 507
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDH-----FPVFKKT 1048
G + RS E+ +F + A DGG+ L+ N++V+V V+D ND+ +PV T
Sbjct: 508 SGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQTGT 567
Query: 1049 WYNFN-VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
V A ++ KV A D D GQNA L+Y +Q + FE+ G + +
Sbjct: 568 SVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQ 627
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ + K LTVV DNG
Sbjct: 628 VTDKDAVKQKLTVVVEDNG 646
Score = 45.6 bits (103), Expect = 0.011
Identities = 64/212 (30%), Positives = 95/212 (44%), Gaps = 26/212 (12%)
Query: 199 LVIMASGK---RIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV------ 249
LV +A G+ I +E+ + I QDLG+ L SG R +FS DS
Sbjct: 19 LVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQ---RLKSGKAR-IFSRDSTEYIELN 74
Query: 250 -NGSLFLEKELDLDAEHNLQANTFVLQVQASQ-LNNPLKTAQARVEIELLDLNDNLPEFE 307
N L L KE +D E +L A T + L+NP++ + +E+ D+NDN P F+
Sbjct: 75 RNTGLLLIKE-KMDRE-SLCAKTTPCALHLQMILDNPMELYT--ITVEITDINDNAPNFQ 130
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN-- 365
+ I E+ G + A D D G N +Y L P F ++ +S +N
Sbjct: 131 KRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSL-KPTDKFRLELQSQADGSKNVE 189
Query: 366 ---QTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
Q LDRE SS + + A + +P + GT
Sbjct: 190 MILQKALDREMQSSFTLLLEAFDGGDPVLSGT 221
Score = 37.5 bits (83), Expect = 2.8
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 38/219 (17%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-------- 124
G+ +S+ +S+TV I DVNDN P+F + Y V E G F +
Sbjct: 425 GVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARV 484
Query: 125 ----------GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
G S++ ++V + +R+FD + D H+ V D G L
Sbjct: 485 SYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYE----TLKDFHFR-VKAQDGGSPPL 539
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVI-MASGKRIHKEIL--------FPEPIHAIDQDL 225
S+ + KV D D Q++ + +G + EI+ + A+D D
Sbjct: 540 SSN-----VTVKVTVQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDS 594
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKEL-DLDA 263
G A L Y+L DR LF + NG + +++ D DA
Sbjct: 595 GQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDA 633
>UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to
ENSANGP00000011295; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000011295 - Nasonia
vitripennis
Length = 1949
Score = 116 bits (279), Expect = 5e-24
Identities = 145/572 (25%), Positives = 245/572 (42%), Gaps = 85/572 (14%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
++I + D N+N P F H Y I E S +GT ++ + ATDAD G NA +Y +
Sbjct: 766 ISITVRDVNNNAPAFAHDLYTASIPELSPVGTVVEE---LTATDADSGINAELVYRIQKG 822
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK 890
G F V+E +G V F+ LD +++ Y + ++A D G L+ L+I + + ND
Sbjct: 823 GFNDFAVNETSGAV-FVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKP 881
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
P F+ + ++V E GT FT ++ A+D D P L N I I
Sbjct: 882 PYFSPGTQRAEV---TEDTAIGTV-FTTLK-------AIDPDSTDPEAL---NFAISEPI 927
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE 1010
A+D NGQ +++ K +F ++ + G V V +SL +
Sbjct: 928 ---TAID----RNGQ--------------RVNDSTTAFKDFFAVDRKTGQVSVVKSLDRD 966
Query: 1011 SEFRLNISALDGGNLNDNI-----SVRVFVKDVNDHFPVFKKTW------YNFNVEEAQY 1059
++++ + + ++ V + DVN P F + W Y+ ++E Q
Sbjct: 967 IAATVSLTLVVTDTSAPTLQQGKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQP 1026
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
T ++G ATDAD N Y I+P F I+ +TG++ + +D E + T
Sbjct: 1027 TGAIVGAFTATDAD---NNIAGYAIEPPSP--YFHINNVTGIVRTSQIIDYEETKQLEFT 1081
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
VVA D G +VND PKF +H + N + +
Sbjct: 1082 VVAYDTG-VPQLSTSAKVTVTIINVNDEDPKF---------EHKSYNATVKENSQPGTRV 1131
Query: 1180 PVYKATIEENAPIG-TTVAKVFANDTDF-IGNGNGLILY---SLPQRKNQQNLGLPSLSS 1234
V KA + P G T + + + +DF IG+ G I ++ R+ + + ++S
Sbjct: 1132 TVVKAIDADEGPFGEVTYSLIGEHASDFNIGHETGEITVGGATVLDREIIPEITISVMAS 1191
Query: 1235 TAILMVT--VADVPDEVEMSD----KPVFISRYYELEIEEN--VNAPVELVSLNLTEHYE 1286
M + VP +++ D +P+F Y + EN VN P ++ + ++ E
Sbjct: 1192 DNAPMNSRRSTSVPVVIKLVDVNDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDE 1251
Query: 1287 --NFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
N ++ Y I+ N+ +F ++P G LY
Sbjct: 1252 GVNGEVWYKIIKGNENG---SFALNPETGILY 1280
Score = 102 bits (245), Expect = 7e-20
Identities = 126/486 (25%), Positives = 202/486 (41%), Gaps = 44/486 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL + V VT+++ ND +P F + Y ++K N++ GT + VKA+D D G G V Y
Sbjct: 1091 QLSTSAKVTVTIINVNDEDPKFEHKS-YNATVKENSQPGTRVTVVKAIDADEGPFGEVTY 1149
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLA 553
L S F I TG ++V + +L+ + V ASD S R S+
Sbjct: 1150 SLIGEH----ASDFNIGHETGEITVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVP 1205
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG--TSVGQIRV--NDAFEQNDVSYD 609
VV V N+ P F Y V N+ + + Q+R ND +V Y
Sbjct: 1206 VVIKLV--DVNDNR---PIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYK 1260
Query: 610 LLHGYEEGVPFAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
++ G E G FA+ +G++ V L R EA + N V V+
Sbjct: 1261 IIKGNENG-SFALNPETGILYPAVSLLGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIP 1319
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG-NGTGNVRFLIANQQ-DV 726
VN + + V EN + + G NG + + N+
Sbjct: 1320 VNQHKPEFIMPELPNATVEVPENGGEPNYLVMTVKAIDRDSGDNGKVSYHMKVGNRNVQE 1379
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
T++ +I E G + + LDRE ++ + + ++A + + + +T+ + D NDN P
Sbjct: 1380 TEEFSINQETGELRAKIILDRETKNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVP 1439
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKEMFDVDENTG 844
F + Y + EN + + A D DEG +A ++ Y G F +D++ G
Sbjct: 1440 EF-YEEYNFNVPENRPKDYYV---GKVTAEDKDEGRHAKVYYYIKAGNADRAFYIDKSDG 1495
Query: 845 VVKFIGDSLDREKKIMYKLSLVA----------RDTGGLSSEAE-----LIIMIGDENDN 889
+ + S DREK+ Y L+++A +DT E + I I DENDN
Sbjct: 1496 SI-YTNRSFDREKRDSYLLTILAANDPDIYVDPKDTDHSRKNLEHGYVNVTIKILDENDN 1554
Query: 890 KPEFNQ 895
P F +
Sbjct: 1555 PPAFER 1560
Score = 91.9 bits (218), Expect = 1e-16
Identities = 114/431 (26%), Positives = 183/431 (42%), Gaps = 47/431 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVG--TVIGKVKAVDPDLGQNGMVLYDLQ 500
V V + L+D NDN P+F + Y S+ N V I +V+AVD D G NG V Y +
Sbjct: 1204 VPVVIKLVDVNDNRPIFTQHS-YRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYKII 1262
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPAN-PSERRYSLAVVTIE 558
+ + F +NP TG + A S + + + + VEA D P ++ V I
Sbjct: 1263 KGNE---NGSFALNPETGILYPAVSLLGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIP 1319
Query: 559 VTRGTKGNKPD--IPDFMGAPYEFWVGSNVGIGTS-VGQIRV--NDAFEQNDVSYDLLHG 613
V + +KP+ +P+ A E V N G V ++ D+ + VSY + G
Sbjct: 1320 VNQ----HKPEFIMPELPNATVE--VPENGGEPNYLVMTVKAIDRDSGDNGKVSYHMKVG 1373
Query: 614 ---YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVD 668
+E F++ + +G + L R + ++ VA + + T TV ++D
Sbjct: 1374 NRNVQETEEFSINQETGELRAKIILDRETKNKFELVLVAADHGSPTAYETLRLLTVLLID 1433
Query: 669 VNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
ND + + F+V EN +G++ T G ++ A D
Sbjct: 1434 TNDN----VPEFYEEYNFNVPENRPKDYYVGKV--TAEDKDEGRHAKVYYYIKAGNADRA 1487
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA------------GIYQVTI 775
I DG+I+T + DREKRD Y +T++A + + G VTI
Sbjct: 1488 FYID-KSDGSIYTNRSFDREKRDSYLLTILAANDPDIYVDPKDTDHSRKNLEHGYVNVTI 1546
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
I DENDNPP FE + Y + + I ++ + A+DAD G N Y +
Sbjct: 1547 KILDENDNPPAFERSAYFAGVNSMANIN---ELVTKVTASDADLGDNGTLQYYVASANLY 1603
Query: 836 MFDVDENTGVV 846
+ D+ +G +
Sbjct: 1604 KYGSDKPSGSI 1614
Score = 84.6 bits (200), Expect = 2e-14
Identities = 55/165 (33%), Positives = 86/165 (52%), Gaps = 9/165 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + T + +D E+ TV+A ++ GV + +VT+ I + ND P FEH +Y
Sbjct: 1062 GIVRTSQIIDYEETKQLEFTVVA-YDTGVPQLSTSAKVTVTIINVNDEDPKFEHKSYNAT 1120
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS-LD 854
+ ENS+ GT + ++KA DADEG Y+L GE F++ TG + G + LD
Sbjct: 1121 VKENSQPGTRV---TVVKAIDADEGPFGEVTYSLIGEHASDFNIGHETGEITVGGATVLD 1177
Query: 855 REKKIMYKLSLVARDTGGL----SSEAELIIMIGDENDNKPEFNQ 895
RE +S++A D + S+ ++I + D NDN+P F Q
Sbjct: 1178 REIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFTQ 1222
Score = 78.6 bits (185), Expect = 1e-12
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 15/181 (8%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
++ + A+D DSG NG++ Y K+ ++ F IN+ G + L
Sbjct: 1350 VMTVKAIDRDSGDNGKVSYHM---------KVGNRNVQETEEFSINQETGELRAKIILDR 1400
Query: 1010 ESE--FRLNISALDGGNLNDNISVR---VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
E++ F L + A D G+ ++R V + D ND+ P F + YNFNV E + +
Sbjct: 1401 ETKNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEE-YNFNVPENRPKDYYV 1459
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
GKV A D D G++A + Y+I+ + D F I G + N DRE D Y+LT++A +
Sbjct: 1460 GKVTAEDKDEGRHAKVYYYIKAGNADRAFYIDKSDGSIYTNRSFDREKRDSYLLTILAAN 1519
Query: 1125 N 1125
+
Sbjct: 1520 D 1520
Score = 76.6 bits (180), Expect = 5e-12
Identities = 71/287 (24%), Positives = 132/287 (45%), Gaps = 20/287 (6%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F P+ +D + + Y ++ GN +F +DS +G + + K +D ++ +
Sbjct: 690 FEPPLRVQARDRDKTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTNGGDSI 749
Query: 274 -LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L VQAS + + +A + I + D+N+N P F D Y SI E P G V ++ ATD
Sbjct: 750 SLTVQAS---DGTFSDKALISITVRDVNNNAPAFAHDLYTASIPELSPVGTVVEELTATD 806
Query: 333 KDQGENGEFTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-KETNP 388
D G N E Y++ KG F+++ SG + V + LD + ++ ++V A + +P
Sbjct: 807 ADSGINAELVYRIQ--KGGFNDFAVNETSGAVFVSRK--LDYDQRNTYHVEVIAFDKGSP 862
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGT-----KTENIEYYDEQLMSF- 442
S+ GT + +P + ++ +GT K + + D + ++F
Sbjct: 863 SLTGTTTLMINVENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFA 922
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL 489
++ +T +D N V + ++ + K G V VK++D D+
Sbjct: 923 ISEPITAIDRNGQR-VNDSTTAFKDFFAVDRKTGQV-SVVKSLDRDI 967
Score = 69.3 bits (162), Expect = 8e-10
Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 6/146 (4%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F +++V G + + +D + L+ QL+ A+V + ++++ND
Sbjct: 1055 FHINNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLST-----SAKVTVTIINVNDED 1109
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLT 362
P+FE YN ++ EN G V V A D D+G GE TY L + F+I +G +T
Sbjct: 1110 PKFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSLIGEHASDFNIGHETGEIT 1169
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNP 388
V TVLDRE + + V A + P
Sbjct: 1170 VGGATVLDREIIPEITISVMASDNAP 1195
Score = 68.5 bits (160), Expect = 1e-09
Identities = 110/486 (22%), Positives = 202/486 (41%), Gaps = 46/486 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V++ ++L DAND+ P F Y + A+ +V+A D D + + Y +
Sbjct: 658 VSLRLSLADANDSPPKFQHKK-YRAVIDEGAEKFEPPLRVQARDRD--KTSKITYSIVEG 714
Query: 503 SNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYS-LAVVTIEVT 560
+ + I F+I+ ++G +++A+ +P+ ++ S+ +S A+++I V
Sbjct: 715 NKMGI---FRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQASDGTFSDKALISITV- 770
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV-- 618
R N P F Y + +GT V ++ DA + ++ +L++ ++G
Sbjct: 771 RDVNNNAPA---FAHDLYTASIPELSPVGTVVEELTATDA--DSGINAELVYRIQKGGFN 825
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
FAV E SG + V L R Y E +A + + +L+ T ++V + ND+
Sbjct: 826 DFAVNETSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPPYFS 885
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIA--------NQQDVT 727
G E + AIG +F T + +I + T + F I+ N Q V
Sbjct: 886 PGTQRA------EVTEDTAIGTVF-TTLKAIDPDSTDPEALNFAISEPITAIDRNGQRVN 938
Query: 728 DDIAIAED--------GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
D +D G + K LDR+ +T++ G + + I D
Sbjct: 939 DSTTAFKDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQGKGNLVVTIID 998
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
N P F + ++ E I+ A A + N + Y + F +
Sbjct: 999 VNHFAPEFARPWTREDPKYSIEMQEEQPTGAIVGAFTATDADNNIAGYAI-EPPSPYFHI 1057
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+ TG+V+ +D E+ + ++VA DTG LS+ A++ + I + ND P+F
Sbjct: 1058 NNVTGIVR-TSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKVTVTIINVNDEDPKFEHKS 1116
Query: 898 ENSKVR 903
N+ V+
Sbjct: 1117 YNATVK 1122
Score = 65.7 bits (153), Expect = 9e-09
Identities = 47/148 (31%), Positives = 73/148 (49%), Gaps = 6/148 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D G + Y LI G F++ G + + LD E + V+
Sbjct: 1134 VKAIDADEGPFGEVTYSLI-GEHASDFNIGHETGEITVGGATVLDREIIPEITISVMASD 1192
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG--FSVLQVMATDKDQ 335
+ +N+ T+ V I+L+D+NDN P F Y S+ ENL +LQV A D D+
Sbjct: 1193 NAPMNSRRSTS-VPVVIKLVDVNDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDE 1251
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWL 361
G NGE Y++ + G+F+++P +G L
Sbjct: 1252 GVNGEVWYKIIKGNENGSFALNPETGIL 1279
Score = 64.9 bits (151), Expect = 2e-08
Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 15/173 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGN----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ AID+D G + Y + GN + + FS++ G L + LD + + N F
Sbjct: 1353 VKAIDRDSGDNGKVSYHMKVGNRNVQETEEFSINQETGELRAKIILDRETK-----NKFE 1407
Query: 274 LQVQASQLNNPLKTAQARV-EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L + A+ +P R+ + L+D NDN+PEF + YN ++ EN P + V +V A D
Sbjct: 1408 LVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEE-YNFNVPENRPKDYYVGKVTAED 1466
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
KD+G + + Y + + AF ID G ++ DRE S + + A
Sbjct: 1467 KDEGRHAKVYYYIKAGNADRAFYIDKSDG--SIYTNRSFDREKRDSYLLTILA 1517
Score = 64.1 bits (149), Expect = 3e-08
Identities = 110/463 (23%), Positives = 178/463 (38%), Gaps = 47/463 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN GT + + A+D D G G++ Y E + + + E+ G
Sbjct: 1121 VKENSQPGTRVTVVKAIDADEGPFGEVTYSLIGE-HASDFNIGHETGEI-------TVGG 1172
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLND--NISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
++ R + P E +++ A D +N + SV V +K DVND+ P+F + Y +V
Sbjct: 1173 ATVLDREIIP--EITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFTQHSYRASVA 1230
Query: 1056 E--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + + +V A D D G N + Y I + + F ++P TG+L L +
Sbjct: 1231 ENLSVNPPAPILQVRAVDNDEGVNGEVWYKIIKGNENGSFALNPETGILYPAVSLLGRAQ 1290
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y + V ARD VN + P+F + L E E
Sbjct: 1291 -SYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKPEFIMPE--LPNATVEVPENGGEPN 1347
Query: 1174 ESVMMIPVYKATIEENAPIG--TTVAKVFANDTD--FIGNGNGLILYSL---PQRKNQQN 1226
VM + +N + V +T+ I G + + + KN+
Sbjct: 1348 YLVMTVKAIDRDSGDNGKVSYHMKVGNRNVQETEEFSINQETGELRAKIILDRETKNKFE 1407
Query: 1227 L-------GLPSLSST-AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
L G P+ T +L V + D D V P F Y + EN +
Sbjct: 1408 LVLVAADHGSPTAYETLRLLTVLLIDTNDNV-----PEFYEE-YNFNVPENRPKDYYVGK 1461
Query: 1279 LNLTEHYENFKMR-YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ + E + YY + + D R F ID +G++Y RS DRE +D+Y + + A
Sbjct: 1462 VTAEDKDEGRHAKVYYYIKAGNAD--RAFYIDKSDGSIYTNRSFDREKRDSYLLTILAAN 1519
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
P +++ G V V ++I D NDN P F
Sbjct: 1520 DPDIYVDPKDTDHSRKNLEHGY----VNVTIKILDENDNPPAF 1558
Score = 62.9 bits (146), Expect = 7e-08
Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 992 FVINERHGHVIVARSLPPE--------SEFRLNISALDGGNLNDNISVRVFVKDVNDHFP 1043
F I+ G + +A+ P + L + A DG +D + + V+DVN++ P
Sbjct: 720 FRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQASDG-TFSDKALISITVRDVNNNAP 778
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F Y ++ E V+ ++ ATDAD G NA L Y IQ + F ++ +G +
Sbjct: 779 AFAHDLYTASIPELSPVGTVVEELTATDADSGINAELVYRIQKGGFN-DFAVNETSGAVF 837
Query: 1104 VNGELDRETEDKYILTVVARDNG 1126
V+ +LD + + Y + V+A D G
Sbjct: 838 VSRKLDYDQRNTYHVEVIAFDKG 860
Score = 59.7 bits (138), Expect = 6e-07
Identities = 83/346 (23%), Positives = 154/346 (44%), Gaps = 40/346 (11%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF--LIAPI 124
+V G+ Q+S VTV I +VND P F Y+ TV E + G + + + A
Sbjct: 1082 VVAYDTGVPQLSTSAKVTVTIINVNDEDPKFEHKSYNATVKENSQPGTRVTVVKAIDADE 1141
Query: 125 GPSLTIPLT-VPRGLTIFK------DIR---AFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
GP + + + + F +I A D+ P ++ S+++ ++ +
Sbjct: 1142 GPFGEVTYSLIGEHASDFNIGHETGEITVGGATVLDREIIP--EITISVMASDNAPMNSR 1199
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATL 231
S+ PV++ K++D + F + + + P PI A+D D GV +
Sbjct: 1200 RSTSVPVVI--KLVDVNDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEV 1257
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL-NNPLKTAQA 290
Y++I GN+ F+L+ G L+ L L +A ++ ++V+A +
Sbjct: 1258 WYKIIKGNENGSFALNPETGILYPAVSL-LG-----RAQSYKIKVEARDMAGKGPHFDTC 1311
Query: 291 RVEIELLDLNDNLPEF---EVDFYNISIVEN--LPNGFSVLQVMATDKDQGENGEFTYQL 345
+ + ++ +N + PEF E+ + + EN PN + V+ V A D+D G+NG+ +Y +
Sbjct: 1312 NIYVRVIPVNQHKPEFIMPELPNATVEVPENGGEPN-YLVMTVKAIDRDSGDNGKVSYHM 1370
Query: 346 D------DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
FSI+ +G L R + +LDRE + + + A +
Sbjct: 1371 KVGNRNVQETEEFSINQETGEL--RAKIILDRETKNKFELVLVAAD 1414
Score = 52.4 bits (120), Expect = 9e-05
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN-----LQANTF 272
+ A D+D G A + Y + +GN + F +D +GS++ + D + + L AN
Sbjct: 1462 VTAEDKDEGRHAKVYYYIKAGNADRAFYIDKSDGSIYTNRSFDREKRDSYLLTILAANDP 1521
Query: 273 VLQVQASQLNNPLKTAQ---ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ V ++ K + V I++LD NDN P FE Y + V +V
Sbjct: 1522 DIYVDPKDTDHSRKNLEHGYVNVTIKILDENDNPPAFERSAYFAGVNSMANINELVTKVT 1581
Query: 330 ATDKDQGENGEFTY 343
A+D D G+NG Y
Sbjct: 1582 ASDADLGDNGTLQY 1595
Score = 51.2 bits (117), Expect = 2e-04
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 726 VTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFN--KGVISGAGIYQVTIYIEDEND 782
+TD + + G + KPLDRE+ D R V E + +G + + + DEND
Sbjct: 425 LTDKFVVDQRTGVMTLAKPLDREEADTIRFRVTLEDSVPQGQQPNIVGVEAHVIVLDEND 484
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTN---ALFMYTLFGEGKEMFD 838
NPP F YE + E+S GT I I+ TD D G N F + F
Sbjct: 485 NPPQFLGVPYEAVVAEDSPPGTTIL--PAIRVTDPDLLGENIQVTCIPQPQFPDACTKFG 542
Query: 839 V-----DENTGV-VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
+ ++T + + LD +++ Y+L L A D G S+ + I + D ++ PE
Sbjct: 543 IVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQASD-GSNSNSTGVEIKVTDIQNSPPE 601
Query: 893 F 893
F
Sbjct: 602 F 602
Score = 51.2 bits (117), Expect = 2e-04
Identities = 49/205 (23%), Positives = 94/205 (45%), Gaps = 20/205 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF---NSEVYIPPSKLSADALEVKRYFVI 994
F +PEN P + K+ A D D G + ++ Y N++ K S ++ R F
Sbjct: 1447 FNVPENRPKDYYVGKVTAEDKDEGRHAKVYYYIKAGNADRAFYIDK-SDGSIYTNRSFDR 1505
Query: 995 NERHGHVI-VARSLPPESEFRLNISALDGGNLNDN-ISVRVFVKDVNDHFPVFKKTWYNF 1052
+R +++ + + P+ + NL ++V + + D ND+ P F+++ Y
Sbjct: 1506 EKRDSYLLTILAANDPDIYVDPKDTDHSRKNLEHGYVNVTIKILDENDNPPAFERSAYFA 1565
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFI-----------QPSDTDL--PFEISPLT 1099
V ++ KV A+DAD G N L Y++ +PS + + PF ++
Sbjct: 1566 GVNSMANINELVTKVTASDADLGDNGTLQYYVASANLYKYGSDKPSGSIVPSPFNVTQ-D 1624
Query: 1100 GVLSVNGELDRETEDKYILTVVARD 1124
G L +G + +D++I+ +VA++
Sbjct: 1625 GKLVTSGYMAEYNQDRFIVEIVAKE 1649
Score = 49.6 bits (113), Expect = 6e-04
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 14/141 (9%)
Query: 419 YVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTV 478
YV P +N+E+ +VNV + +LD NDN P F S Y + S A + +
Sbjct: 1524 YVDPKDTDHSRKNLEH------GYVNVTIKILDENDNPPAFERS-AYFAGVNSMANINEL 1576
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA 538
+ KV A D DLG NG + Y + ++NL +K + + S+ SP + V
Sbjct: 1577 VTKVTASDADLGDNGTLQYYV-ASANL-----YKYGSDKPSGSIVPSPFNVTQDGKLV-T 1629
Query: 539 SDQPANPSERRYSLAVVTIEV 559
S A ++ R+ + +V E+
Sbjct: 1630 SGYMAEYNQDRFIVEIVAKEI 1650
Score = 47.6 bits (108), Expect = 0.003
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 20/186 (10%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
EPI AID++ G + + D F++D G + + K LD D + V
Sbjct: 925 EPITAIDRN---GQRVNDSTTAFKD--FFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTD 979
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEF------EVDFYNISIVENLPNGFSVLQVM 329
A L + + + ++D+N PEF E Y+I + E P G V
Sbjct: 980 TSAPTLQQ----GKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQPTGAIVGAFT 1035
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
ATD D G Y ++ P F I+ +G VR ++D E L V A +T
Sbjct: 1036 ATDADNNIAG---YAIEPPSPYFHINNVTG--IVRTSQIIDYEETKQLEFTVVAYDTGVP 1090
Query: 390 VVGTFA 395
+ T A
Sbjct: 1091 QLSTSA 1096
Score = 43.2 bits (97), Expect = 0.056
Identities = 48/184 (26%), Positives = 76/184 (41%), Gaps = 18/184 (9%)
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V A+ N +T + + L D ND+ P+F+ Y I E L+V A D
Sbjct: 641 VTSESATDDNGKGQTTSVSLRLSLADANDSPPKFQHKKYRAVIDEGAEKFEPPLRVQARD 700
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD----REAHSSLRMKVYAKETNP 388
+D+ ++ + G F ID SG +T+ + +D S+ + V A +
Sbjct: 701 RDKTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQASD--- 757
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPL---EKTTYVFPD--KVGTKTENIEYYDEQLMSFV 443
GTF+D I+ R + NAP + T P+ VGT E + D S +
Sbjct: 758 ---GTFSDKALISITVRD-VNNNAPAFAHDLYTASIPELSPVGTVVEELTATDAD--SGI 811
Query: 444 NVEV 447
N E+
Sbjct: 812 NAEL 815
Score = 37.9 bits (84), Expect = 2.1
Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
S D+ G+L L++ LD Q L +QAS +N T VEI++ D+ ++ P
Sbjct: 549 SQDTYIGALVLQQPLDYKERPFYQ-----LLLQASDGSNSNSTG---VEIKVTDIQNSPP 600
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
EF +D + E+ P G V+ V A D D+G + Y+L
Sbjct: 601 EF-LDSLTGVVKEDDPIGTLVMTVKARDGDRGMPRKIVYEL 640
>UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadherin
LKC; n=2; Gallus gallus|Rep: PREDICTED: similar to
protocadherin LKC - Gallus gallus
Length = 1497
Score = 115 bits (277), Expect = 9e-24
Identities = 137/472 (29%), Positives = 200/472 (42%), Gaps = 40/472 (8%)
Query: 451 DANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITS 509
D NDN PVF NL YE S+ N VG+VI V A D D G V Y +Q T T
Sbjct: 316 DRNDNAPVF--QNLPYETSVLENTTVGSVIYTVFANDSDTGTAARVSYSIQEVIPDT-TK 372
Query: 510 PFKINPNTGTVSVAESPILEGRHALFVEAS--DQPANPSERRYSLAVVTIEVTRGTKGNK 567
++ + SV + L+ F + Q R ++ + T +
Sbjct: 373 NHRLFYILSSGSVVLNNSLDYTMNTFFQLKILAQDGGGLLRNETVIQSSTTYLSITVIDV 432
Query: 568 PDI-PDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEE 624
P++ P F+ PY V +GT+V + D + +SY + VPFA+ +
Sbjct: 433 PNLDPRFLNEPYSGSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFTNA---SVPFAIND 489
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-------TVHVVDVNDERGVLL 677
+G ITV L R P + L +NL I N TV V DVND +
Sbjct: 490 TTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFY 549
Query: 678 KGAHSPIIFHVKENSAGAAI----GQIFHTNMSSIYGN---GTGNVRFLIANQQDVTDDI 730
+ + + H + N G+ I ++ +N+S + + GT N F + Q
Sbjct: 550 QCSSNCNFIHTQSNFTGSIIEHSSSKVPVSNLSIVARDPDKGT-NGTFELYLQGTSASAF 608
Query: 731 AIAED---GT----IFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
++ GT I Q P +D E V + +IA VTI + D N
Sbjct: 609 TVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTN 668
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVD 840
D+ P F +TY +MENS GT I + I A D D G + Y L E +E+F V+
Sbjct: 669 DHIPEFPQSTYNLRVMENSPDGTIIATN--ITAYDPDSGASGQITYQLLPESIQEIFMVN 726
Query: 841 ENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+G V G LDRE + +Y +L A+D G + L I + D+NDN+P
Sbjct: 727 ATSGAVLVRNGSLLDREMRPVYYANLQAKDGGNMMGTTLLEITVLDKNDNEP 778
Score = 107 bits (256), Expect = 3e-21
Identities = 164/728 (22%), Positives = 293/728 (40%), Gaps = 100/728 (13%)
Query: 581 WVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNR 640
+V ++ IG Q+ D + + ++Y + + F ++GV+T+ + L R ++
Sbjct: 233 YVAEDLQIGEFAFQLMAYD-IDGDTITYSI--SGSDSFYFTANAQTGVVTLRNLLDRESQ 289
Query: 641 PMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
V + + N ++ + V D ND V + P V EN+ +G +
Sbjct: 290 ARLTI-LVTVSDGINEAVSRRLPIIVEDRNDNAPVF---QNLPYETSVLENTT---VGSV 342
Query: 701 FHTNMSSIYGNGTGNVRFLIANQQDVTDDIA------IAEDGTIFTQKPLDREKRDVYRM 754
+T ++ GT R + Q+ + D I G++ LD +++
Sbjct: 343 IYTVFANDSDTGTA-ARVSYSIQEVIPDTTKNHRLFYILSSGSVVLNNSLDYTMNTFFQL 401
Query: 755 TVIAEFNKGVISGAGIYQ-----VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
++A+ G++ + Q ++I + D + P F + Y G + E +GT +
Sbjct: 402 KILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLT- 460
Query: 810 NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK--LSLVA 867
+ A D D G N Y+ F F +++ TG + + LDRE+ + L ++A
Sbjct: 461 --VTAMDRDTGVNDKISYS-FTNASVPFAINDTTGTIT-VSQVLDREQLPSEEVLLEVLA 516
Query: 868 RDT-----GGLSSEAELI-IMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
R++ G ++ + L+ +++ D NDNKP+F Q N IH ++ G +IIE
Sbjct: 517 RESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNF-IHTQSNFTG----SIIEH 571
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+P+ + + A D D G NG E+Y+ +
Sbjct: 572 S------------------SSKVPVSN--LSIVARDPDKGTNGTF------ELYLQGT-- 603
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFR----LNISALDGGNLND---NISVRVF 1034
SA A V ++ ++V + E + + A D GN D +V +
Sbjct: 604 SASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLIANDTGNPTDCCSTATVTID 663
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG-KVDATDADFGQNANLTYFIQPSDTDLPF 1093
+ D NDH P F ++ YN V E ++ + A D D G + +TY + P F
Sbjct: 664 LIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQITYQLLPESIQEIF 723
Query: 1094 EISPLTG-VLSVNGE-LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ +G VL NG LDRE Y + A+D G D NDN P
Sbjct: 724 MVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGG---NMMGTTLLEITVLDKNDNEPII 780
Query: 1152 YA--FDELLEWKHPEADELSNHNFE-----SVMMIPVYKATIEENAPIGTTVAK---VFA 1201
F + E ++ + N E S + + N I T + +
Sbjct: 781 IGSYFISVEEGQNVSTQIRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEP 840
Query: 1202 NDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRY 1261
D + + + G ++ ++ + G+P LS+ + +TVADV D + PVF+ +
Sbjct: 841 LDREAVDDEAGQMVVTV----EVYDHGVPQLSTMVNVTITVADVND-----NTPVFLQQS 891
Query: 1262 YELEIEEN 1269
YE I E+
Sbjct: 892 YEFSIFES 899
Score = 80.6 bits (190), Expect = 3e-13
Identities = 128/561 (22%), Positives = 228/561 (40%), Gaps = 72/561 (12%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG-KVKAVDPDLGQNGMVLYDL 499
S V + L+D ND+ P F P + Y + N+ GT+I + A DPD G +G + Y L
Sbjct: 656 STATVTIDLIDTNDHIPEF-PQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQITYQL 714
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
S I F +N +G V V +L+ A+ Q + + +E+
Sbjct: 715 LPES---IQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGN---MMGTTLLEI 768
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGV 618
T K + P +G+ Y V + T + I ++ N ++ + ++ G
Sbjct: 769 TVLDKNDNE--PIIIGS-YFISVEEGQNVSTQIRAIDNDEEGTPNSELGFKIVPGLYSN- 824
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEA------VALQENA--NLSIVTNATVHVVDVN 670
F + + +G + ++ L +R D EA V + ++ LS + N T+ V DVN
Sbjct: 825 NFTISQTTGELHNIEPL---DREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVN 881
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN---------MSSIYGNGTGNVRFLIA 721
D V L+ ++ F + E+S G+ +G + T+ +S TG+ FLI+
Sbjct: 882 DNTPVFLQQSYE---FSIFESSDGSFVGDVMATDADRTEINSRISFQLEKSTGSSNFLIS 938
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--D 779
+ + + + + + ++ + V+AE N + I V++ + D
Sbjct: 939 SSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAE-NTAADNSGNIANVSVLVNILD 997
Query: 780 ENDNPPVFEHATYEGF-IMENSKIGTEIKMDNIIKATDADEGTNALF---MYTLFGEGKE 835
ND PP ++ EG + EN GT+ + + + A+D D + +F + G
Sbjct: 998 VNDEPPTIVPSSLEGVSVREN---GTQQDLVHTVFASDRDTNHSLVFEELSVACYKGGSS 1054
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+V + V+ G L I Y+L V +L + + D K NQ
Sbjct: 1055 AGEVCWDWFVLLPNGSVLANSFDIDYELCDV----------VQLTMRVEDLYTQKG--NQ 1102
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
+N ++I II++ L V G ++PE P+ + + A
Sbjct: 1103 YSQNETLQIR------------IIDINDNAPVFLPVS--GTFVVVPEISPVDLQVATVKA 1148
Query: 956 LDLDSGLNGQIRYEFNSEVYI 976
D DSGL G + + S V +
Sbjct: 1149 TDADSGLEGTVFFNIISVVLV 1169
Score = 78.6 bits (185), Expect = 1e-12
Identities = 141/568 (24%), Positives = 222/568 (39%), Gaps = 59/568 (10%)
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
TV T +DR+ + + K+ TN SV D+ + P E+
Sbjct: 457 TVLTVTAMDRD--TGVNDKISYSFTNASVPFAINDTTGTITVSQVLDREQLPSEEVLL-- 512
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF--VPSNLYEFSMKSN------- 472
+V + N++ Y + V V + D NDN P F SN +SN
Sbjct: 513 --EVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIE 570
Query: 473 ---AKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT-SPFKINPNTGTVSV-AESPI 527
+KV + A DPD G NG LQ TS T SP +I TG V + ++P
Sbjct: 571 HSSSKVPVSNLSIVARDPDKGTNGTFELYLQGTSASAFTVSPTRI-VGTGEVQILVQNPS 629
Query: 528 ---LEGRHALFVE-ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVG 583
E H + V+ ++ NP++ S A VTI++ IP+F + Y V
Sbjct: 630 AVDYEITHVMVVQLIANDTGNPTD-CCSTATVTIDLI----DTNDHIPEFPQSTYNLRVM 684
Query: 584 SNVGIGTSVG-QIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDD--LSRY 638
N GT + I D+ ++Y LL + + F V SG + V + L R
Sbjct: 685 ENSPDGTIIATNITAYDPDSGASGQITYQLLPESIQEI-FMVNATSGAVLVRNGSLLDRE 743
Query: 639 NRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
RP+Y + + ++ N+ T + V+D ND +++ G++ V+E G +
Sbjct: 744 MRPVY-YANLQAKDGGNMMGTTLLEITVLDKNDNEPIII-GSY---FISVEE---GQNVS 795
Query: 699 QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD--VYRMTV 756
+ G + F I + G + +PLDRE D +M V
Sbjct: 796 TQIRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVV 855
Query: 757 IAE-FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK---IG--------- 803
E ++ GV + + VTI + D NDN PVF +YE I E+S +G
Sbjct: 856 TVEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFESSDGSFVGDVMATDADR 915
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
TEI + + +N L + G G + N GV ++ ++
Sbjct: 916 TEINSRISFQLEKSTGSSNFLISSSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLA 975
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKP 891
A D G + +++ I D ND P
Sbjct: 976 ENTAADNSGNIANVSVLVNILDVNDEPP 1003
Score = 75.8 bits (178), Expect = 9e-12
Identities = 44/128 (34%), Positives = 72/128 (56%), Gaps = 5/128 (3%)
Query: 270 NTFVLQVQASQLNNPLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV-LQ 327
+ V+Q+ A+ NP A V I+L+D ND++PEF YN+ ++EN P+G +
Sbjct: 637 HVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATN 696
Query: 328 VMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ A D D G +G+ TYQL + + F ++ SG + VRN ++LDRE + AK+
Sbjct: 697 ITAYDPDSGASGQITYQLLPESIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKD 756
Query: 386 TNPSVVGT 393
+++GT
Sbjct: 757 -GGNMMGT 763
Score = 63.3 bits (147), Expect = 5e-08
Identities = 57/205 (27%), Positives = 97/205 (47%), Gaps = 13/205 (6%)
Query: 218 IHAIDQDLGVGATLRY---ELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D G A + Y E+I + + +LF + S +GS+ L LD Q
Sbjct: 346 VFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILS-SGSVVLNNSLDYTMNTFFQLK-I 403
Query: 273 VLQVQASQLNNP--LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
+ Q L N ++++ + I ++D+ + P F + Y+ S+ E P G +VL V A
Sbjct: 404 LAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLTVTA 463
Query: 331 TDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSS--LRMKVYAKETNP 388
D+D G N + +Y + F+I+ +G +TV VLDRE S + ++V A+E+N
Sbjct: 464 MDRDTGVNDKISYSFTNASVPFAINDTTGTITV--SQVLDREQLPSEEVLLEVLARESNL 521
Query: 389 SVVGTFADSQRIAKWRRQPLETNAP 413
+ G A + + + N P
Sbjct: 522 DIYGNVAQASTLVTVLVTDVNDNKP 546
Score = 55.6 bits (128), Expect = 1e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 218 IHAIDQDL-GV-GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I AID D G + L ++++ G F++ G L + LD +A + +A V+
Sbjct: 798 IRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDD-EAGQMVVT 856
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+ P + V I + D+NDN P F Y SI E+ F V VMATD D+
Sbjct: 857 VEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFESSDGSF-VGDVMATDADR 915
Query: 336 GE-NGEFTYQLDDPKGA 351
E N ++QL+ G+
Sbjct: 916 TEINSRISFQLEKSTGS 932
Score = 48.4 bits (110), Expect = 0.002
Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G T+ Y ISG+D F+ ++ G + L LD ++ QA +L + +N +
Sbjct: 254 GDTITYS-ISGSDSFYFTANAQTGVVTLRNLLDRES----QARLTILVTVSDGIN---EA 305
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
R+ I + D NDN P F+ Y S++EN G + V A D D G +Y + +
Sbjct: 306 VSRRLPIIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVFANDSDTGTAARVSYSIQE 365
Score = 44.8 bits (101), Expect = 0.018
Identities = 52/197 (26%), Positives = 94/197 (47%), Gaps = 30/197 (15%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D GV + Y N F+++ G++ + + LD + L + +L+V
Sbjct: 461 VTAMDRDTGVNDKISYSFT--NASVPFAINDTTGTITVSQVLDRE---QLPSEEVLLEVL 515
Query: 278 ASQLNNPL--KTAQARVEIELL--DLNDNLPEF-----EVDFYNI------SIVENLPNG 322
A + N + AQA + +L D+NDN P+F +F + SI+E+ +
Sbjct: 516 ARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSK 575
Query: 323 FSV--LQVMATDKDQGENGEFTYQLDDPK-GAFSIDPR----SG--WLTVRNQTVLDREA 373
V L ++A D D+G NG F L AF++ P +G + V+N + +D E
Sbjct: 576 VPVSNLSIVARDPDKGTNGTFELYLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEI 635
Query: 374 HSSLRMKVYAKET-NPS 389
+ +++ A +T NP+
Sbjct: 636 THVMVVQLIANDTGNPT 652
Score = 44.8 bits (101), Expect = 0.018
Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 11/158 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G + Y+L+ + +++F +++ +G++ + LD E + +Q
Sbjct: 697 ITAYDPDSGASGQITYQLLPESIQEIFMVNATSGAVLVRNGSLLDRE---MRPVYYANLQ 753
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A N + T +EI +LD NDN P + Y IS+ E N + ++ + D++
Sbjct: 754 AKDGGNMMGT--TLLEITVLDKNDNEP-IIIGSYFISVEEG-QNVSTQIRAIDNDEEGTP 809
Query: 338 NGEFTYQLDDP--KGAFSIDPRSGWLTVRNQTVLDREA 373
N E +++ F+I +G L N LDREA
Sbjct: 810 NSELGFKIVPGLYSNNFTISQTTGEL--HNIEPLDREA 845
Score = 42.7 bits (96), Expect = 0.075
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +T++D + +P F+ + Y S+ VGT + V A+D D G N + Y S
Sbjct: 425 LSITVIDVPNLDPRFL-NEPYSGSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFTNAS- 482
Query: 505 LTITSPFKINPNTGTVSVAE 524
PF IN TGT++V++
Sbjct: 483 ----VPFAINDTTGTITVSQ 498
Score = 40.3 bits (90), Expect = 0.40
Identities = 45/166 (27%), Positives = 77/166 (46%), Gaps = 15/166 (9%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALE--VKRYFVINERHG 999
E I IG+ I +++ ++ QIR N E P S+L + F I++ G
Sbjct: 777 EPIIIGSYFI---SVEEGQNVSTQIRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTG 833
Query: 1000 HVIVARSLPPES------EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ L E+ + + + D G L+ ++V + V DVND+ PVF + Y
Sbjct: 834 ELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYE 893
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEIS 1096
F++ E+ +G V ATDAD + N+ +++ ++ S F IS
Sbjct: 894 FSIFESS-DGSFVGDVMATDADRTEINSRISFQLEKSTGSSNFLIS 938
Score = 39.1 bits (87), Expect = 0.92
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE 108
G+ Q+S ++VT+ + DVNDN P+FL Y ++ E
Sbjct: 863 GVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFE 898
Score = 37.5 bits (83), Expect = 2.8
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 12/120 (10%)
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVT 1241
Y ++ E P+GTTV V A D D N I YS N +P + +T
Sbjct: 444 YSGSVPEGCPVGTTVLTVTAMDRD--TGVNDKISYSF------TNASVPFAINDTTGTIT 495
Query: 1242 VADVPDEVEMSDKPVF---ISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEN 1298
V+ V D ++ + V ++R L+I NV LV++ +T+ +N K ++Y + N
Sbjct: 496 VSQVLDREQLPSEEVLLEVLARESNLDIYGNVAQASTLVTVLVTDVNDN-KPQFYQCSSN 554
Score = 37.5 bits (83), Expect = 2.8
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 132 LTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS----HKPVLLLRKV 187
++V G + IRA D D+ TPNS++ + IV G +F + + H L R+
Sbjct: 786 ISVEEGQNVSTQIRAIDNDEEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREA 845
Query: 188 LDYDAG 193
+D +AG
Sbjct: 846 VDDEAG 851
Score = 36.7 bits (81), Expect = 4.9
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
LV + G+N+ + + + +ED NDN P+F + PY +V E T G
Sbjct: 295 LVTVSDGINE-AVSRRLPIIVEDRNDNAPVFQNLPYETSVLENTTVG 340
>UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1326
Score = 115 bits (277), Expect = 9e-24
Identities = 122/468 (26%), Positives = 206/468 (44%), Gaps = 29/468 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L + VT+LD++D++PVF ++ Y+ S+ N VG I +V+A DPD G NG +
Sbjct: 217 DPVLSGVTTLNVTVLDSDDHSPVFDRTS-YQVSVAENIGVGQHIIQVRASDPDTGTNGQI 275
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLA 553
+YD + + I F+I+ +G +SV E H + + A++ NP ++
Sbjct: 276 IYDFGGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVT 335
Query: 554 VVTIEVTRGTKGNKPDIP-DFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
V I+V NKP + +G F + N V +RV D + +L
Sbjct: 336 VNLIDV----NDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTD-MDTGVNGQAIL 390
Query: 612 HGYEEGVPFAVEE-RSG--VITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVV 667
++ F +E R G + L R + Y+ +A + LS V V
Sbjct: 391 TLEDDFGHFYLESFREGQYFLKTAGVLDREDIDFYNITILAEDRGSPVLSSRRRFAVFVD 450
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
D ND + + I + N G + + + + G V + + + +D +
Sbjct: 451 DENDNSPIFSSSVYHATI--SENNEPGHRVATVQAIDKDEL---ENGEVVYSLLDDKDGS 505
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I +G + LDRE + + +I ++G G +T+ + D NDN P F
Sbjct: 506 FGIH-PFNGVLTANVSLDREDGESIDL-MIRACDRGQPQGCSDVPLTVRVLDMNDNGPTF 563
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
E I EN GT + ATDADEG N Y++ + +F +DE++G +
Sbjct: 564 GGDLIEMRIDENKPSGTIV---GRAVATDADEGDNGRLRYSILTDA--VFRIDEDSGRI- 617
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ LDRE + +Y ++ A D G ++ A +++ + D ND+ PEF
Sbjct: 618 YSTAELDREIQELYHFTVRAVDDGLSPKTATATVVVTVNDGNDHSPEF 665
Score = 90.2 bits (214), Expect = 4e-16
Identities = 111/414 (26%), Positives = 171/414 (41%), Gaps = 54/414 (13%)
Query: 744 LDREKRDVYRMTVIAEFNKG-VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE +D Y MT+ A+ V+SG VT+ D +D+ PVF+ +Y+ + EN +
Sbjct: 198 LDRENKDNYVMTLYADDGGDPVLSGVTTLNVTVL--DSDDHSPVFDRTSYQVSVAENIGV 255
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
G I ++A+D D GTN +Y FG G V KI+ +
Sbjct: 256 GQHIIQ---VRASDPDTGTNGQIIYD-FG------------GSVS---------AKII-E 289
Query: 863 LSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
L + ++G LS ++EL D D +Q+ + + T +I+V
Sbjct: 290 LFEIDSESGWLSVKSEL-----DFEDESS--HQVSIRATNNVPNPLPDFTTVTVNLIDVN 342
Query: 923 PKNKFALDVDQLGP---LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS 979
NK L + LG I EN P + + D+D+G+NGQ +
Sbjct: 343 D-NKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLEDDF----G 397
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKD 1037
++ +YF+ + V+ + + + I A D G+ L+ VFV D
Sbjct: 398 HFYLESFREGQYFL---KTAGVLDREDI---DFYNITILAEDRGSPVLSSRRRFAVFVDD 451
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ P+F + Y+ + E + V A D D +N + Y + D D F I P
Sbjct: 452 ENDNSPIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVYSLL-DDKDGSFGIHP 510
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
GVL+ N LDRE + L + A D G D+NDN P F
Sbjct: 511 FNGVLTANVSLDREDGESIDLMIRACDRG-QPQGCSDVPLTVRVLDMNDNGPTF 563
Score = 75.8 bits (178), Expect = 9e-12
Identities = 54/185 (29%), Positives = 92/185 (49%), Gaps = 16/185 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSL---DSVNGSLFLEKEL--DLDAEHNLQANTFVL 274
A D+D+G A Y L S + F L + G + ++ E+ LD E+ + +V+
Sbjct: 153 ASDEDIGENAIQGYRL-SDEYAETFGLVQNEFPGGLIIIQLEVIGSLDRENK---DNYVM 208
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A +P+ + + + +LD +D+ P F+ Y +S+ EN+ G ++QV A+D D
Sbjct: 209 TLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASDPD 268
Query: 335 QGENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
G NG+ Y A F ID SGWL+V+++ LD E SS ++ + A P+
Sbjct: 269 TGTNGQIIYDFGGSVSAKIIELFEIDSESGWLSVKSE--LDFEDESSHQVSIRATNNVPN 326
Query: 390 VVGTF 394
+ F
Sbjct: 327 PLPDF 331
Score = 75.4 bits (177), Expect = 1e-11
Identities = 123/460 (26%), Positives = 188/460 (40%), Gaps = 53/460 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE++ GT A D D G N Y + E Y L + E +I +
Sbjct: 138 IPESVVPGTRFPLSTASDEDIGENAIQGYRLSDE-YAETFGLVQN--EFPGGLIIIQLE- 193
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VI + + + + + A DGG+ L+ ++ V V D +DH PVF +T Y +V E
Sbjct: 194 -VIGSLDRENKDNYVMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAEN 252
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY----FIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ + +V A+D D G N + Y + +L FEI +G LSV ELD E E
Sbjct: 253 IGVGQHIIQVRASDPDTGTNGQIIYDFGGSVSAKIIEL-FEIDSESGWLSVKSELDFEDE 311
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK--FYAFDELLEWKH-----PEAD 1166
+ +++ A +N DVNDN P+ A + +KH PE
Sbjct: 312 SSHQVSIRATNN-VPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFKHIAENSPEDV 370
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK---N 1223
+++ + +A + G + F F+ L +
Sbjct: 371 DVAYVRVTDMDTGVNGQAILTLEDDFGHFYLESFREGQYFLKTAGVLDREDIDFYNITIL 430
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP---VELVSLN 1280
++ G P LSS V V D E + P+F S Y I EN N P V V
Sbjct: 431 AEDRGSPVLSSRRRFAVFVDD-----ENDNSPIFSSSVYHATISEN-NEPGHRVATVQAI 484
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ EN ++ Y +L++ D +F I P NG L S DRE ++ ++++RA
Sbjct: 485 DKDELENGEVVYSLLDDKD----GSFGIHPFNGVLTANVSLDREDGESIDLMIRA----C 536
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
R P +G + DV + VR+ D+NDN P F
Sbjct: 537 DRGQP-----------QGCS--DVPLTVRVLDMNDNGPTF 563
Score = 72.9 bits (171), Expect = 6e-11
Identities = 85/321 (26%), Positives = 136/321 (42%), Gaps = 19/321 (5%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S ++ V + D +D+ P+F T Y V+V E G+ + +
Sbjct: 220 LSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASDPDTGTNGQIIYDF 279
Query: 137 GLTIF-KDIRAFDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD--Y 190
G ++ K I F+ D + + S++ + S + A + P+ V
Sbjct: 280 GGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVTVNLI 339
Query: 191 DAGDKEFQLVIMA---SGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLF 244
D D + +L I A G+ H PE + + D+ G + L +D F
Sbjct: 340 DVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLEDDFGHF 399
Query: 245 SLDSVN-GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
L+S G FL+ LD E + + + + A +P+ +++ R + + D NDN
Sbjct: 400 YLESFREGQYFLKTAGVLDRE---DIDFYNITILAEDRGSPVLSSRRRFAVFVDDENDNS 456
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLT 362
P F Y+ +I EN G V V A DKD+ ENGE Y LDD G+F I P +G LT
Sbjct: 457 PIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVYSLLDDKDGSFGIHPFNGVLT 516
Query: 363 VRNQTVLDREAHSSLRMKVYA 383
LDRE S+ + + A
Sbjct: 517 A--NVSLDREDGESIDLMIRA 535
Score = 68.1 bits (159), Expect = 2e-09
Identities = 73/269 (27%), Positives = 115/269 (42%), Gaps = 22/269 (8%)
Query: 1015 LNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L I A D G ++ + V V D+ND+ P F ++E + + ++G+ ATDA
Sbjct: 531 LMIRACDRGQPQGCSDVPLTVRVLDMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDA 590
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
D G N L Y I TD F I +G + ELDRE ++ Y TV A D+G
Sbjct: 591 DEGDNGRLRYSIL---TDAVFRIDEDSGRIYSTAELDREIQELYHFTVRAVDDG-LSPKT 646
Query: 1133 XXXXXXXXXXDVNDNSPKFYAFDELLEWKH-PEADELSNHNFESVMMIPVYKATIEENAP 1191
D ND+SP+F + + P + + H +M + +ENA
Sbjct: 647 ATATVVVTVNDGNDHSPEFIVPSAKNDIRFIPVSADPGLH----IMTVESEDEDKDENAA 702
Query: 1192 IGTTVAKVFANDTDFI-GNGNGLILYSL-PQRKNQQNL-------GLPSLSSTAILMVTV 1242
+ ++ N I NG + L P + ++ G PS SSTA+L V +
Sbjct: 703 VSYAISHGNTNGAFGIQANGQVVTAQDLEPMWEGVHDITIRATDGGNPSASSTAVLRVVI 762
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVN 1271
A+ + + S P + + L I+ +N
Sbjct: 763 AN--EGFKRSLPPANFTALFNLTIDYYLN 789
Score = 67.7 bits (158), Expect = 2e-09
Identities = 52/185 (28%), Positives = 82/185 (44%), Gaps = 14/185 (7%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G + Y+ +S +LF +DS +G L ++ ELD + E + Q +
Sbjct: 262 VRASDPDTGTNGQIIYDFGGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRA- 320
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-----IVENLPNGFSVLQVM 329
+ + NPL V + L+D+NDN P + I EN P V V
Sbjct: 321 ---TNNVPNPLPDFTT-VTVNLIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVR 376
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDP-RSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
TD D G NG+ L+D G F ++ R G ++ VLDRE + + A++
Sbjct: 377 VTDMDTGVNGQAILTLEDDFGHFYLESFREGQYFLKTAGVLDREDIDFYNITILAEDRGS 436
Query: 389 SVVGT 393
V+ +
Sbjct: 437 PVLSS 441
Score = 66.9 bits (156), Expect = 4e-09
Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 9/166 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID+D + Y L+ D F + NG L LD + ++ L ++
Sbjct: 481 VQAIDKDELENGEVVYSLLDDKDGS-FGIHPFNGVLTANVSLDREDGESID-----LMIR 534
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + + + +LD+NDN P F D + I EN P+G V + +ATD D+G+
Sbjct: 535 ACDRGQPQGCSDVPLTVRVLDMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDADEGD 594
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
NG Y + F ID SG + + LDRE V A
Sbjct: 595 NGRLRYSI-LTDAVFRIDEDSG--RIYSTAELDREIQELYHFTVRA 637
Score = 56.4 bits (130), Expect = 6e-06
Identities = 49/180 (27%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 220 AIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D + + A + ++ N+ SLDS G L LDLD E ++ + +++
Sbjct: 45 ADDLAITIDANTEFSMLGVPNETAYVSLDSQTGEL--TTVLDLDREELCPGSSALCEIEV 102
Query: 279 SQLNNPLKTAQA-RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + L T + V++ + D+ND+ PEF D N+SI E++ G A+D+D GE
Sbjct: 103 NAIE--LGTREVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDIGE 160
Query: 338 NGEFTYQLDDPK----GAFSIDPRSGWLTVRNQTV--LDREAHSSLRMKVYAKETNPSVV 391
N Y+L D G + G + ++ + + LDRE + M +YA + V+
Sbjct: 161 NAIQGYRLSDEYAETFGLVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYADDGGDPVL 220
Score = 55.6 bits (128), Expect = 1e-05
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
+ ++A++ G + I+V+V + D+NDH P F+ N ++ E+ A+D D
Sbjct: 100 IEVNAIELGT-REVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDI 158
Query: 1075 GQNANLTYFIQPSDTDL------PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
G+NA Y + + F + L V G LDRE +D Y++T+ A D+G
Sbjct: 159 GENAIQGYRLSDEYAETFGLVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYA-DDGGD 217
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKF 1151
D +D+SP F
Sbjct: 218 PVLSGVTTLNVTVLDSDDHSPVF 240
Score = 51.2 bits (117), Expect = 2e-04
Identities = 55/192 (28%), Positives = 86/192 (44%), Gaps = 15/192 (7%)
Query: 715 NVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQ 772
N F + + T +++ ++ G + T LDRE+ + E N + +
Sbjct: 55 NTEFSMLGVPNETAYVSLDSQTGELTTVLDLDREELCPGSSALCEIEVNAIELGTREVIT 114
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V + I D ND+ P F I E+ GT + A+D D G NA+ Y L E
Sbjct: 115 VKVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLST---ASDEDIGENAIQGYRLSDE 171
Query: 833 GKEMFDVDENT---GVV----KFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMI 883
E F + +N G++ + IG SLDRE K Y ++L A D G LS L + +
Sbjct: 172 YAETFGLVQNEFPGGLIIIQLEVIG-SLDRENKDNYVMTLYADDGGDPVLSGVTTLNVTV 230
Query: 884 GDENDNKPEFNQ 895
D +D+ P F++
Sbjct: 231 LDSDDHSPVFDR 242
Score = 50.4 bits (115), Expect = 4e-04
Identities = 77/283 (27%), Positives = 116/283 (40%), Gaps = 31/283 (10%)
Query: 629 ITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ V+ L R N+ Y A + LS VT V V+D +D V + ++
Sbjct: 192 LEVIGSLDRENKDNYVMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQ---VS 248
Query: 688 VKEN-SAGAAIGQI------FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
V EN G I Q+ TN IY G G+V I ++ +E G +
Sbjct: 249 VAENIGVGQHIIQVRASDPDTGTNGQIIYDFG-GSVSAKIIELFEID-----SESGWLSV 302
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE-HATYEG----F 795
+ LD E +++++ A N VT+ + D NDN P A +G
Sbjct: 303 KSELDFEDESSHQVSIRAT-NNVPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFKH 361
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF--DVDENTGVVKFIGDSL 853
I ENS ++ ++ TD D G N + TL + + E +K G L
Sbjct: 362 IAENSPEDVDVAY---VRVTDMDTGVNGQAILTLEDDFGHFYLESFREGQYFLKTAG-VL 417
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
DRE Y ++++A D G LSS + + DENDN P F+
Sbjct: 418 DREDIDFYNITILAEDRGSPVLSSRRRFAVFVDDENDNSPIFS 460
Score = 44.8 bits (101), Expect = 0.018
Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 13/151 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G LRY +++ +F +D +G ++ ELD + + + V+A
Sbjct: 587 ATDADEGDNGRLRYSILTD---AVFRIDEDSGRIYSTAELDREIQE-----LYHFTVRAV 638
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS---IVENLPNGFSVLQVMATDKDQG 336
KTA A V + + D ND+ PEF V I + G ++ V + D+D+
Sbjct: 639 DDGLSPKTATATVVVTVNDGNDHSPEFIVPSAKNDIRFIPVSADPGLHIMTVESEDEDKD 698
Query: 337 ENGEFTYQLD--DPKGAFSIDPRSGWLTVRN 365
EN +Y + + GAF I +T ++
Sbjct: 699 ENAAVSYAISHGNTNGAFGIQANGQVVTAQD 729
Score = 39.1 bits (87), Expect = 0.92
Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Query: 445 VEVTLLDANDNNPVF-VPSNLYEFS-MKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V VT+ D ND++P F VPS + + +A G I V++ D D +N V Y +
Sbjct: 651 VVVTVNDGNDHSPEFIVPSAKNDIRFIPVSADPGLHIMTVESEDEDKDENAAVSYAI--- 707
Query: 503 SNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S+ F I N V+ + P+ EG H + + A+D NPS ++ V I
Sbjct: 708 SHGNTNGAFGIQANGQVVTAQDLEPMWEGVHDITIRATD-GGNPSASSTAVLRVVI-ANE 765
Query: 562 GTKGNKP 568
G K + P
Sbjct: 766 GFKRSLP 772
>UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9;
Theria|Rep: dachsous 2 isoform 1 - Bos Taurus
Length = 2131
Score = 115 bits (276), Expect = 1e-23
Identities = 117/501 (23%), Positives = 218/501 (43%), Gaps = 42/501 (8%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTEN---IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNL 464
L T +PL++ P V T T + + D +L S + +V +LD ND++P F +
Sbjct: 328 LVTTSPLDRERV--PTVVLTVTASDQAVNVTDRRLRSLM-AKVVILDVNDHSPTFTSFPI 384
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-LQRTSNLTITSPFKINPNTGTVSVA 523
++ +A VG+++ + A DPD G+NG V + L N+ F ++ ++G ++ A
Sbjct: 385 AH--VREDAAVGSLVHHITAQDPDAGRNGRVTFSILSGNENMA----FMLDESSGFLTTA 438
Query: 524 ESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF 580
SP+ ++ +H L + A D +L + ++V + P F YE
Sbjct: 439 -SPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDV-------NDEAPVFKQHLYEA 490
Query: 581 WVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRY 638
V N G V ++ D+ + + ++++ G + F + +G + L R
Sbjct: 491 SVKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPG-ASFMLFQINSDTGEVVTAATLDRE 549
Query: 639 NRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
+ + L + ++ TV + V DE + V EN +
Sbjct: 550 VQEVLTLR--VLVHDGGAPALSGTTVILCTVRDENDHAPQIVVPRDDIEVLENQEPGLVY 607
Query: 699 QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVI 757
++M + NG + N + A+ E G + T + LDRE+ + + ++
Sbjct: 608 TFLASDMDA-GSNGAVTYHIIDGNTDEY---FAVNEMSGELSTTRALDREEVSNFTLVIL 663
Query: 758 AEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
+ G + Q+ + + D+ND+ P F Y+ + E++++GT + ++ + D
Sbjct: 664 CS-DLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVL---VLSSADE 719
Query: 818 DEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA 877
DEG N MY+L E F +D G ++ +LDRE + + L VARD G S +
Sbjct: 720 DEGLNGQTMYSLVHESSGAFTIDPVAGTLR-TSRALDREARSEHVLKAVARDCGVQGSRS 778
Query: 878 ELIIM---IGDENDNKPEFNQ 895
+++ + D NDN P Q
Sbjct: 779 TTVVIKVHVTDVNDNSPVLEQ 799
Score = 113 bits (273), Expect = 3e-23
Identities = 126/474 (26%), Positives = 211/474 (44%), Gaps = 33/474 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVLYDL 499
S V + V + D ND++P F S+ N VGT++ A D D N + Y +
Sbjct: 251 STVFLSVAVEDQNDHSPSF-REEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFI 309
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRH---ALFVEASDQPANPSERRYSLAVVT 556
+ +N +PF I+P++GT+ V SP+ R L V ASDQ N ++RR +
Sbjct: 310 E--ANHPGMNPFLIHPSSGTL-VTTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAK 366
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGY 614
+ V + P F A V + +G+ V I D A V++ +L G
Sbjct: 367 V-VILDVNDHSPTFTSFPIAH----VREDAAVGSLVHHITAQDPDAGRNGRVTFSILSG- 420
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDER 673
E + F ++E SG +T L + + +AL LS T+ V+DVNDE
Sbjct: 421 NENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEA 480
Query: 674 GVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V + + VKEN + G + ++ + S + ++F I
Sbjct: 481 PVFKQHLYEA---SVKENQNPGEFVTRVEAVDRDSGINS---KLQFEIMPGASFMLFQIN 534
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++ G + T LDRE ++V + V+ + G + +G + + DEND+ P
Sbjct: 535 SDTGEVVTAATLDREVQEVLTLRVLVH-DGGAPALSGTTVILCTVRDENDHAPQIVVPRD 593
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+ ++EN + G + A+D D G+N Y + G E F V+E +G +
Sbjct: 594 DIEVLENQEPG----LVYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGELSTTR- 648
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+LDRE+ + L ++ D G SS A+L + + D+ND+ P F +++ + VR
Sbjct: 649 ALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVR 702
Score = 109 bits (262), Expect = 6e-22
Identities = 145/602 (24%), Positives = 251/602 (41%), Gaps = 41/602 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S ++V +LD ND++P F P Y+ S++ +A+VGT + + + D D G NG +Y L
Sbjct: 674 STAQLQVRVLDDNDHSPSF-PRLQYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLV 732
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
S + F I+P GT+ + + E R ++A + R + V+ + VT
Sbjct: 733 HES----SGAFTIDPVAGTLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVT 788
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P + P + ++ S + +R +D + + + V
Sbjct: 789 -DVNDNSPVLEQ---NPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSV-L 843
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
++ E +G I + S P++ + A+ + T V ++ D R +
Sbjct: 844 SINEYTGAIQLQQIPSSEYFPIW-LQLKAVDQGVPARTTTGLLVIHMEGEDVRISFSQHL 902
Query: 681 HSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+ I V EN AG +I I SI + +V N+ V + + + T+
Sbjct: 903 YKGI---VPENCEAGTSIVTIKAFAPDSIRDSIKYSV--FSGNEDGVFSLCSKSGEVTVK 957
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
K LD E R ++ V+AE ++G +V ++I+D ND+PP FE + Y+ + E
Sbjct: 958 EPKFLDFEVRKEVQLIVLAE-SRG---RKAYSKVAVFIQDLNDHPPHFEQSVYQVSVSEG 1013
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
I + ATD D G+N L Y+ L G +F +D +GV+ LD E
Sbjct: 1014 QFYNHHIVQ---VFATDLDSGSNGLVEYSILSGNQGNVFQMDPLSGVLT-ASAILDYEYT 1069
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
Y L + A D G LS + I + D NDN P F E V E L GT
Sbjct: 1070 STYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPSEAVEIV----ENSLPGTIVT 1125
Query: 917 TI----IEVKPKNKFA-LDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
I ++ P F+ + G F I N + ++ + LD + +++ + +
Sbjct: 1126 RISVYDVDSNPAFTFSFVKESNSGTKFAIDRNTGV---VVLVETLDFEEATKYELQIQIS 1182
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISV 1031
V+ ++ L+V + + + + L P L I A D + ++NI+
Sbjct: 1183 DLVHQTEGTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVES-SENITY 1241
Query: 1032 RV 1033
R+
Sbjct: 1242 RI 1243
Score = 105 bits (252), Expect = 9e-21
Identities = 127/461 (27%), Positives = 203/461 (44%), Gaps = 66/461 (14%)
Query: 936 PLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
P+ + E+ +G+ + + A D D+G NG++ + S LS + F+++
Sbjct: 383 PIAHVREDAAVGSLVHHITAQDPDAGRNGRVTF----------SILSGNE---NMAFMLD 429
Query: 996 ERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
E G + A L E S+ L + ALDGG L+ + ++ + V DVND PVFK+ Y
Sbjct: 430 ESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEAPVFKQHLYE 489
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
+V+E Q + +V+A D D G N+ L + I P + + F+I+ TG + LDRE
Sbjct: 490 ASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPGASFMLFQINSDTGEVVTAATLDRE 549
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA---FDELLEWKHPE---- 1164
++ L V+ D G D ND++P+ E+LE + P
Sbjct: 550 VQEVLTLRVLVHDGG-APALSGTTVILCTVRDENDHAPQIVVPRDDIEVLENQEPGLVYT 608
Query: 1165 --ADELSNHNFESVMMIPVYKATIEENA--PIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
A ++ + +V + T E A + ++ A D + + N +IL S
Sbjct: 609 FLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGELSTTRALDREEVSNFTLVILCS--- 665
Query: 1221 RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
+LG P SSTA L V V D D P F Y+ + E+ ++ L+
Sbjct: 666 -----DLGSPPQSSTAQLQVRVLDDNDH-----SPSFPRLQYQASVREDAQVGTTVLVLS 715
Query: 1281 LTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ E N + Y +++E+ F IDP GTL R+ DRE R+E
Sbjct: 716 SADEDEGLNGQTMYSLVHESS----GAFTIDPVAGTLRTSRALDRE--------ARSE-- 761
Query: 1339 KYSRELPHMIYPVAEDV-LEGMTKYDVKVVVRIKDVNDNSP 1378
H++ VA D ++G V + V + DVNDNSP
Sbjct: 762 -------HVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSP 795
Score = 96.3 bits (229), Expect = 6e-18
Identities = 55/167 (32%), Positives = 93/167 (55%), Gaps = 8/167 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + Y +I GN + F+++ ++G L + LD + + + F L + S
Sbjct: 611 ASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGELSTTRALDRE-----EVSNFTLVILCS 665
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
L +P +++ A++++ +LD ND+ P F Y S+ E+ G +VL + + D+D+G NG
Sbjct: 666 DLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEGLNG 725
Query: 340 EFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ Y L + GAF+IDP +G T+R LDREA S +K A++
Sbjct: 726 QTMYSLVHESSGAFTIDPVAG--TLRTSRALDREARSEHVLKAVARD 770
Score = 89.8 bits (213), Expect = 5e-16
Identities = 97/404 (24%), Positives = 169/404 (41%), Gaps = 36/404 (8%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++PEN GT+I+ + A DS + I+Y S + D + F + +
Sbjct: 906 IVPENCEAGTSIVTIKAFAPDS-IRDSIKYSVFSG--------NEDGV-----FSLCSKS 951
Query: 999 GHVIVARSLPPESEFRLNISAL---DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G V V + E R + + + V VF++D+NDH P F+++ Y +V
Sbjct: 952 GEVTVKEPKFLDFEVRKEVQLIVLAESRGRKAYSKVAVFIQDLNDHPPHFEQSVYQVSVS 1011
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E Q+ + +V ATD D G N + Y I + F++ PL+GVL+ + LD E
Sbjct: 1012 EGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQGNVFQMDPLSGVLTASAILDYEYTST 1071
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y L V A D G D+NDN+P F EA E+ ++
Sbjct: 1072 YSLIVQAMDKG-MPRLSDTTVIKIQVTDINDNAPIFLP---------SEAVEIVENSLPG 1121
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
++ + ++ N + K + T F I G+++ + +
Sbjct: 1122 TIVTRISVYDVDSNPAFTFSFVKESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQIQI 1181
Query: 1235 TAILMVTVADVPDEV-EMSDK-PVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY 1292
+ ++ T V V +++D PVF Y++ I E V ++++ T+ + + Y
Sbjct: 1182 SDLVHQTEGTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSENITY 1241
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPD-REVKDTYEVIVRA 1335
IL+ + + F +DP NGT++ + E K T +V A
Sbjct: 1242 RILSSS-----KMFSVDPTNGTIFTINPVFLMERKSTIRFLVEA 1280
Score = 88.6 bits (210), Expect = 1e-15
Identities = 112/464 (24%), Positives = 200/464 (43%), Gaps = 42/464 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D NDN P+F+PS E + N+ GT++ ++ D D N + + SN
Sbjct: 1092 IKIQVTDINDNAPIFLPSEAVE--IVENSLPGTIVTRISVYDVD--SNPAFTFSFVKESN 1147
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I+ NTG V + E+ E ++ L ++ SD + +E ++ V+ +
Sbjct: 1148 SG--TKFAIDRNTGVVVLVETLDFEEATKYELQIQISDL-VHQTEGTVTVHVLDVN---- 1200
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P P F Y+ + V +G V I D +++Y +L + F+V
Sbjct: 1201 ---DNP--PVFSQDSYQVTISELVPLGHPVLTIVATDVESSENITYRILSSSKM---FSV 1252
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVND-------ER 673
+ +G I ++ + R V + +L VT + D+N+ E
Sbjct: 1253 DPTNGTIFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQDMNNYAPEFAIEY 1312
Query: 674 GVLLKGAHSPIIFHVKENSA--GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
L +P+ + S + H S I GN N + + +
Sbjct: 1313 YNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFH---VETSFIHSEYS 1369
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G + LDRE + + ++A F+ G + V+I + D +DNPP F
Sbjct: 1370 YKQVGYLVLLHHLDREATASHELVLLA-FDHGCPPLSSSATVSIEVLDVDDNPPAFSSLE 1428
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIG 850
Y I E++ G+ I ++ A+D D G++A Y L G K+ F ++E TGV+ I
Sbjct: 1429 YYVHIKESTPPGSPI---IVVSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTGVLSLI- 1484
Query: 851 DSLDREKKIMYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEF 893
LD E+ I + L++ A D S A + + + D+ND+ P+F
Sbjct: 1485 KPLDYEETIKFILTVQASDEERKHFSFAIVFVNVLDDNDHAPQF 1528
Score = 85.0 bits (201), Expect = 1e-14
Identities = 115/471 (24%), Positives = 205/471 (43%), Gaps = 39/471 (8%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ V V + D ND+ P F S +Y+ S+ I +V A D D G NG+V Y +
Sbjct: 983 AYSKVAVFIQDLNDHPPHFEQS-VYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSIL 1041
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + F+++P +G ++ + E ++L V+A D+ R V+ I+
Sbjct: 1042 SGNQGNV---FQMDPLSGVLTASAILDYEYTSTYSLIVQAMDKGM---PRLSDTTVIKIQ 1095
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
VT + P F+ + V +++ GT V +I V D ++ + G
Sbjct: 1096 VT----DINDNAPIFLPSEAVEIVENSLP-GTIVTRISVYDVDSNPAFTFSFVKESNSGT 1150
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLK 678
FA++ +GV+ +V+ L Y+ + + + + + + T TVHV+DVND V +
Sbjct: 1151 KFAIDRNTGVVVLVETLDFEEATKYELQ-IQISDLVHQTEGT-VTVHVLDVNDNPPVFSQ 1208
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
++ I + G + I T++ S + N+ + I + + +GTI
Sbjct: 1209 DSYQVTISELVP--LGHPVLTIVATDVES-----SENITYRILSSSKMFS--VDPTNGTI 1259
Query: 739 FTQKPLD-REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
FT P+ E++ R V A + G + V I+D N+ P F Y +
Sbjct: 1260 FTINPVFLMERKSTIRFLVEAS-DGGFPDLKAVTLVETEIQDMNNYAPEFAIEYYNLSLS 1318
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD----ENTGVVKFIG--- 850
E++ +G + + I E T+ + + G + F V+ + K +G
Sbjct: 1319 EDTPVGRTLVTFSTIDHDWTRENTHVEYSI-ISGNSQNNFHVETSFIHSEYSYKQVGYLV 1377
Query: 851 --DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
LDRE ++L L+A D G LSS A + I + D +DN P F+ +E
Sbjct: 1378 LLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLE 1428
Score = 83.0 bits (196), Expect = 6e-14
Identities = 114/466 (24%), Positives = 190/466 (40%), Gaps = 34/466 (7%)
Query: 445 VEVTLLDANDNNPVF----VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
V V++ D NDN P F LY + V ++ V A D D G N V+Y +
Sbjct: 39 VHVSVTDINDNRPYFPQCLAGKELY-VKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSV- 96
Query: 501 RTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
S+ + FKI+ N+G + S + + V ASDQ P + + AV+ I+
Sbjct: 97 --SSEDSSDHFKIDANSGEIRTTRVLSRDYGPSYRMTVIASDQGVPPLQGQ---AVINIQ 151
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ---NDVSYDLLHGYE 615
V +KG + + N+ + I+ D ++ + + + +
Sbjct: 152 VIPLSKGRTVISQNIR----HLVIPENLKPTKVMSLIKSPDHLQRQHGGKLHFSIAADDK 207
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERG 674
+G F V+ +G + + +L Y V + N + N+TV + V V D+
Sbjct: 208 DG-HFEVDSSTGDLFLSKELDYEMMSHYLLRVVTKDHSRNPPV--NSTVFLSVAVEDQND 264
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE 734
I+ V EN+ + IF+ + F+ AN + +
Sbjct: 265 HSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFIEANHPGMNPFLIHPS 324
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI--YQVTIYIEDENDNPPVFEHATY 792
GT+ T PLDRE+ +TV A ++ + + I D ND+ P F
Sbjct: 325 SGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAKVVILDVNDHSPTFTSFPI 384
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIGD 851
+ E++ +G+ + + I A D D G N +++ + M F +DE++G +
Sbjct: 385 -AHVREDAAVGSLV---HHITAQDPDAGRNGRVTFSILSGNENMAFMLDESSGFLT-TAS 439
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LD E K + L+L+A D G LSS L I + D ND P F Q
Sbjct: 440 PLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEAPVFKQ 485
Score = 79.8 bits (188), Expect = 5e-13
Identities = 103/443 (23%), Positives = 191/443 (43%), Gaps = 40/443 (9%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD-SGLNG 964
R +N T F + V+ +N + + + +PEN P+GT + NA D D S LN
Sbjct: 245 RNPPVNSTV-FLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNS 303
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDG 1022
+I+Y +I + + F+I+ G ++ L E L ++A D
Sbjct: 304 RIQY------FIEANHPGMNP------FLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQ 351
Query: 1023 G-NLND----NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
N+ D ++ +V + DVNDH P F ++ +V E ++ + A D D G+N
Sbjct: 352 AVNVTDRRLRSLMAKVVILDVNDHSPTFT-SFPIAHVREDAAVGSLVHHITAQDPDAGRN 410
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
+T+ I + ++ F + +G L+ LD E + ++ILT++A D G
Sbjct: 411 GRVTFSILSGNENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGG-TPTLSSSQTL 469
Query: 1138 XXXXXDVNDNSPKF--YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE-ENAPIGT 1194
DVND +P F + ++ ++ + ++ E+V + ++ E P +
Sbjct: 470 TITVLDVNDEAPVFKQHLYEASVKENQNPGEFVT--RVEAVDRDSGINSKLQFEIMPGAS 527
Query: 1195 TVAKVFANDTDFIGNGNGL---ILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEM 1251
+ +DT + L + L R + G P+LS T +++ TV D D
Sbjct: 528 FMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDENDHA-- 585
Query: 1252 SDKPVFISRYYELEIEENVNAPVELVSL-NLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
P + ++E+ EN + L + + N + Y+I++ N TD F ++
Sbjct: 586 ---PQIVVPRDDIEVLENQEPGLVYTFLASDMDAGSNGAVTYHIIDGN-TD--EYFAVNE 639
Query: 1311 RNGTLYLVRSPDREVKDTYEVIV 1333
+G L R+ DRE + +++
Sbjct: 640 MSGELSTTRALDREEVSNFTLVI 662
Score = 78.6 bits (185), Expect = 1e-12
Identities = 91/366 (24%), Positives = 150/366 (40%), Gaps = 38/366 (10%)
Query: 991 YFVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVF 1045
+F ++ G + +++ L E S + L + D +N + + V V+D NDH P F
Sbjct: 210 HFEVDSSTGDLFLSKELDYEMMSHYLLRVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSF 269
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFG-QNANLTYFIQPSDTDL-PFEISPLTGVLS 1103
++ + +V E ++ +A D D N+ + YFI+ + + PF I P +G L
Sbjct: 270 REEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFIEANHPGMNPFLIHPSSGTLV 329
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX--DVNDNSPKFYAFDELLEWK 1161
LDRE +LTV A D DVND+SP F +F +
Sbjct: 330 TTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAKVVILDVNDHSPTFTSFPIAHVRE 389
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-- 1219
L +H I N + ++ N + +G + + P
Sbjct: 390 DAAVGSLVHH-------ITAQDPDAGRNGRVTFSILSGNENMAFMLDESSGFLTTASPLD 442
Query: 1220 -QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
+ K+Q L G P+LSS+ L +TV DV DE PVF YE ++EN N
Sbjct: 443 YEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEA-----PVFKQHLYEASVKENQN 497
Query: 1272 APVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD-- 1327
+ + + N K+++ I+ + F I+ G + + DREV++
Sbjct: 498 PGEFVTRVEAVDRDSGINSKLQFEIMPGASFML---FQINSDTGEVVTAATLDREVQEVL 554
Query: 1328 TYEVIV 1333
T V+V
Sbjct: 555 TLRVLV 560
Score = 75.4 bits (177), Expect = 1e-11
Identities = 72/273 (26%), Positives = 123/273 (45%), Gaps = 27/273 (9%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+++Y + SGN+ +FSL S +G + +++ LD E + VL + A
Sbjct: 931 SIKYSVFSGNEDGVFSLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESRG------RKAY 984
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG--EFTYQLDD 347
++V + + DLND+ P FE Y +S+ E ++QV ATD D G NG E++ +
Sbjct: 985 SKVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGN 1044
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQP 407
F +DP SG LT +LD E S+ + V A + + +D+ + K +
Sbjct: 1045 QGNVFQMDPLSGVLTA--SAILDYEYTSTYSLIVQAMDKG---MPRLSDT-TVIKIQVTD 1098
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
+ NAP+ P +E +E + L + +++ D D+NP F S + E
Sbjct: 1099 INDNAPI-----FLP------SEAVEIVENSLPGTIVTRISVYDV-DSNPAFTFSFVKES 1146
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ + + G V V+ L Y+LQ
Sbjct: 1147 NSGTKFAIDRNTGVVVLVE-TLDFEEATKYELQ 1178
Score = 73.7 bits (173), Expect = 3e-11
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 12/168 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I D D T + S + K F++D G + L + LD + +A + LQ+Q
Sbjct: 1127 ISVYDVDSNPAFTFSFVKESNSGTK-FAIDRNTGVVVLVETLDFE-----EATKYELQIQ 1180
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
S L + + V + +LD+NDN P F D Y ++I E +P G VL ++ATD + E
Sbjct: 1181 ISDL---VHQTEGTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSE 1237
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N TY++ FS+DP +G + N L E S++R V A +
Sbjct: 1238 N--ITYRILSSSKMFSVDPTNGTIFTINPVFL-MERKSTIRFLVEASD 1282
Score = 73.7 bits (173), Expect = 3e-11
Identities = 59/178 (33%), Positives = 86/178 (48%), Gaps = 18/178 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D+G A + Y L SGN+++ F L+ G L L K LD + + F+L VQ
Sbjct: 1446 VSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTGVLSLIKPLDYE-----ETIKFILTVQ 1500
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS + A V + +LD ND+ P+F N ++ ENLP ++ V A D D G
Sbjct: 1501 ASDEERK-HFSFAIVFVNVLDDNDHAPQFMFPNLNCAVPENLPVFSTICSVNALDFDAGP 1559
Query: 338 NGEFTYQLDDP----------KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+ TY + P F IDP +G + Q VLD E + + V AK+
Sbjct: 1560 YGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTG--DISAQQVLDYENDNKYCLIVQAKD 1615
Score = 73.7 bits (173), Expect = 3e-11
Identities = 41/148 (27%), Positives = 80/148 (54%), Gaps = 7/148 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN+P+ +TI +NALD D+G G + Y + P L + +F+I+ G
Sbjct: 1537 VPENLPVFSTICSVNALDFDAGPYGDMTYSI-----VSPCPLPHEMPHDHNFFLIDPLTG 1591
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E++ + L + A D + ++ V V V+ +++ P+F + Y F++ E
Sbjct: 1592 DISAQQVLDYENDNKYCLIVQAKDKADSTASVVVWVDVEGIDEFEPIFTQDQYFFSLPEK 1651
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQ 1085
+ R ++G+V+A+DAD G + + Y ++
Sbjct: 1652 SHVRHLIGRVEASDADAGVDGVILYSLE 1679
Score = 72.9 bits (171), Expect = 6e-11
Identities = 79/304 (25%), Positives = 138/304 (45%), Gaps = 33/304 (10%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTV------- 134
+VTV++ DVNDN P+F Y VT+ EL P G + + S I +
Sbjct: 1191 TVTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSENITYRILSSSKMF 1250
Query: 135 ---PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
P TIF F ++ +T + + +V +D G L++ L+ ++ D +
Sbjct: 1251 SVDPTNGTIFTINPVFLMERKST----IRF-LVEASDGGFPDLKAV---TLVETEIQDMN 1302
Query: 192 AGDKEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGAT-LRYELISGNDRKLFSL 246
EF + + ++ + + ++ ID D T + Y +ISGN + F +
Sbjct: 1303 NYAPEFAIEYYNLSLSEDTPVGRTLV---TFSTIDHDWTRENTHVEYSIISGNSQNNFHV 1359
Query: 247 D-SVNGSLFLEKELD-LDAEHNLQANTFV---LQVQASQLNNPLKTAQARVEIELLDLND 301
+ S S + K++ L H+L L + A P ++ A V IE+LD++D
Sbjct: 1360 ETSFIHSEYSYKQVGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDD 1419
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
N P F Y + I E+ P G ++ V A+D+D G + E +Y L + K F ++ ++G
Sbjct: 1420 NPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTG 1479
Query: 360 WLTV 363
L++
Sbjct: 1480 VLSL 1483
Score = 71.3 bits (167), Expect = 2e-10
Identities = 67/234 (28%), Positives = 101/234 (43%), Gaps = 26/234 (11%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F + EN G + ++ A+D DSG+N ++++E +P +
Sbjct: 474 LDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEI-----MPGASF 528
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL--DGG--NLNDNISVRVFVKD 1037
F IN G V+ A +L E + L + L DGG L+ + V+D
Sbjct: 529 --------MLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRD 580
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
NDH P + V E Q V + A+D D G N +TY I +TD F ++
Sbjct: 581 ENDHAPQIVVPRDDIEVLENQEPGLVYTFL-ASDMDAGSNGAVTYHIIDGNTDEYFAVNE 639
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++G LS LDRE + L ++ D G D ND+SP F
Sbjct: 640 MSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDD-NDHSPSF 692
Score = 68.9 bits (161), Expect = 1e-09
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 6/177 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G + + ++SGN+ F LD +G L LD + + + +L +
Sbjct: 400 ITAQDPDAGRNGRVTFSILSGNENMAFMLDESSGFLTTASPLDYEIK-----SQHILTLL 454
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P ++ + I +LD+ND P F+ Y S+ EN G V +V A D+D G
Sbjct: 455 ALDGGTPTLSSSQTLTITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGI 514
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
N + +++ S V LDRE L ++V + P++ GT
Sbjct: 515 NSKLQFEIMPGASFMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGT 571
Score = 68.1 bits (159), Expect = 2e-09
Identities = 95/407 (23%), Positives = 167/407 (41%), Gaps = 51/407 (12%)
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
I+++ A DLDSG NG + Y S LS + V F ++ G + + L
Sbjct: 1020 IVQVFATDLDSGSNGLVEY----------SILSGNQGNV---FQMDPLSGVLTASAILDY 1066
Query: 1010 E--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E S + L + A+D G L+D +++ V D+ND+ P+F + + E ++
Sbjct: 1067 EYTSTYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPS-EAVEIVENSLPGTIVT 1125
Query: 1066 KVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
++ D D N T+ F++ S++ F I TGV+ + LD E KY L + D
Sbjct: 1126 RISVYDVD--SNPAFTFSFVKESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQIQISD 1183
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKF------YAFDELLEWKHPEADELSNHNFESVMM 1178
DVNDN P F EL+ HP ++ + ES
Sbjct: 1184 ----LVHQTEGTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTIVAT-DVESSEN 1238
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAIL 1238
I + + + T +F + F+ I + + + G P L + ++
Sbjct: 1239 ITYRILSSSKMFSVDPTNGTIFTINPVFLMERKSTIRFLV----EASDGGFPDLKAVTLV 1294
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH---YENFKMRYYIL 1295
+ D+ + P F YY L + E+ LV+ + +H EN + Y I+
Sbjct: 1295 ETEIQDMNNYA-----PEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSII 1349
Query: 1296 ---NENDTDIRRTFVIDPRN----GTLYLVRSPDREVKDTYEVIVRA 1335
++N+ + +F+ + G L L+ DRE ++E+++ A
Sbjct: 1350 SGNSQNNFHVETSFIHSEYSYKQVGYLVLLHHLDREATASHELVLLA 1396
Score = 64.9 bits (151), Expect = 2e-08
Identities = 58/221 (26%), Positives = 102/221 (46%), Gaps = 18/221 (8%)
Query: 940 IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE-- 996
+ E+ P+G T++ + +D D + N + Y S S + V+ F+ +E
Sbjct: 1317 LSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGN-------SQNNFHVETSFIHSEYS 1369
Query: 997 --RHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWY 1050
+ G++++ L E+ L + A D G L+ + +V + V DV+D+ P F Y
Sbjct: 1370 YKQVGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEY 1429
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
+++E+ + V A+D D G +A ++Y++ + F + TGVLS+ LD
Sbjct: 1430 YVHIKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTGVLSLIKPLDY 1489
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E K+ILTV A D D ND++P+F
Sbjct: 1490 EETIKFILTVQASDE--ERKHFSFAIVFVNVLDDNDHAPQF 1528
Score = 63.7 bits (148), Expect = 4e-08
Identities = 82/317 (25%), Positives = 130/317 (41%), Gaps = 25/317 (7%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPY-HVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT 139
L V I DVND+ P F P HV D + G + + ++ G
Sbjct: 363 LMAKVVILDVNDHSPTFTSFPIAHVREDAAVGSLVHHITAQDPDAGRNGRVTFSILSG-- 420
Query: 140 IFKDIRAFDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVL-----LLRKVLDYD 191
+ AF D+ + T S + Y I S + AL+ P L L VLD +
Sbjct: 421 --NENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGG-TPTLSSSQTLTITVLDVN 477
Query: 192 AGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
F Q + AS K F + A+D+D G+ + L++E++ G LF ++S
Sbjct: 478 DEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPGASFMLFQINSDT 537
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G + LD + + L L+V P + + + D ND+ P+ V
Sbjct: 538 GEVVTAATLDREVQEVL-----TLRVLVHDGGAPALSGTTVILCTVRDENDHAPQIVVPR 592
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTV 368
+I ++EN G V +A+D D G NG TY + D F+++ SG L+
Sbjct: 593 DDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGELSTTR--A 649
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE S+ + + +
Sbjct: 650 LDREEVSNFTLVILCSD 666
Score = 61.7 bits (143), Expect = 2e-07
Identities = 66/215 (30%), Positives = 96/215 (44%), Gaps = 33/215 (15%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDVD P F I E+ P G+ II ++A D D G + ++ Y S
Sbjct: 1415 LDVDDNPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSG-------- 1466
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVK--D 1037
K++F + E+ G + + + L E +F L + A D + + ++ VFV D
Sbjct: 1467 -----NEKQHFCLEEKTGVLSLIKPLDYEETIKFILTVQASDEERKHFSFAI-VFVNVLD 1520
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLP-- 1092
NDH P F N V E + V+A D D G ++TY I P ++P
Sbjct: 1521 DNDHAPQFMFPNLNCAVPENLPVFSTICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHD 1580
Query: 1093 ---FEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
F I PLTG +S LD E ++KY L V A+D
Sbjct: 1581 HNFFLIDPLTGDISAQQVLDYENDNKYCLIVQAKD 1615
Score = 59.7 bits (138), Expect = 6e-07
Identities = 114/493 (23%), Positives = 199/493 (40%), Gaps = 74/493 (15%)
Query: 930 DVDQLGPLFLIPENIPI------GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
D++ P+FL E + I GT + +++ D+DS N + F E S
Sbjct: 1098 DINDNAPIFLPSEAVEIVENSLPGTIVTRISVYDVDS--NPAFTFSFVKE--------SN 1147
Query: 984 DALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
+ F I+ G V++ +L E +++ L I D + + +V V V DVND+
Sbjct: 1148 SGTK----FAIDRNTGVVVLVETLDFEEATKYELQIQISDLVHQTEG-TVTVHVLDVNDN 1202
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG- 1100
PVF + Y + E + + ATD + +N +TY I S F + P G
Sbjct: 1203 PPVFSQDSYQVTISELVPLGHPVLTIVATDVESSEN--ITYRILSSSK--MFSVDPTNGT 1258
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
+ ++N E + V A D G D+N+ +P+F L
Sbjct: 1259 IFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQ-DMNNYAPEFAIEYYNLSL 1317
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN-------GNGL 1213
+ F ++ + T E + I F +T FI + G +
Sbjct: 1318 SEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFHVETSFIHSEYSYKQVGYLV 1377
Query: 1214 ILYSLPQRKNQQNL--------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+L+ L + + G P LSS+A + + V DV D + P F S Y +
Sbjct: 1378 LLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDD-----NPPAFSSLEYYVH 1432
Query: 1266 IEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
I+E+ +P+ +VS + + + ++ YY+ + N+ ++ F ++ + G L L++ D
Sbjct: 1433 IKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSGNE---KQHFCLEEKTGVLSLIKPLDY 1489
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
E +T + I+ Q E H + + V V + D ND++P+F
Sbjct: 1490 E--ETIKFILTV--QASDEERKHFSFAI--------------VFVNVLDDNDHAPQFMFP 1531
Query: 1384 NRPLVTAIPTTAP 1396
N L A+P P
Sbjct: 1532 N--LNCAVPENLP 1542
Score = 57.6 bits (133), Expect = 2e-06
Identities = 51/213 (23%), Positives = 88/213 (41%), Gaps = 14/213 (6%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E P+ + + A DLD G N ++ Y +SE K+ A++ E++ V++ +G
Sbjct: 68 EGQPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSGEIRTTRVLSRDYG-- 125
Query: 1002 IVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+R+ + A D G L + + V ++ V + + + E
Sbjct: 126 ---------PSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLK 176
Query: 1060 TRRVLGKVDATDADFGQNANLTYF-IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
+V+ + + D Q+ +F I D D FE+ TG L ++ ELD E Y+L
Sbjct: 177 PTKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFEVDSSTGDLFLSKELDYEMMSHYLL 236
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
VV +D+ D ND+SP F
Sbjct: 237 RVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSF 269
Score = 57.6 bits (133), Expect = 2e-06
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 9/144 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA--EHNLQANTFVLQ 275
+ + D+D G+ Y L+ + F++D V G+L + LD +A EH L+A
Sbjct: 714 LSSADEDEGLNGQTMYSLVHESSGA-FTIDPVAGTLRTSRALDREARSEHVLKAVARDCG 772
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQ S ++ +++ + D+NDN P E + +I + P + + A+D D
Sbjct: 773 VQGS------RSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQSPTNQTAAILRASDPDS 826
Query: 336 GENGEFTYQLDDPKGAFSIDPRSG 359
G NG T+ +P+ SI+ +G
Sbjct: 827 GPNGTVTFSFAEPQSVLSINEYTG 850
Score = 54.8 bits (126), Expect = 2e-05
Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 11/129 (8%)
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV-----DFYNISIVEN 318
+H +A+ V V S +P ++A V + + D+NDN P F + Y + ++E
Sbjct: 12 DHEQRAHHQVA-VLVSDHGSPPRSATTLVHVSVTDINDNRPYFPQCLAGKELY-VKVLEG 69
Query: 319 LPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
P V V A D D+G N E Y + +D F ID SG +R VL R+ S
Sbjct: 70 QPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSG--EIRTTRVLSRDYGPS 127
Query: 377 LRMKVYAKE 385
RM V A +
Sbjct: 128 YRMTVIASD 136
Score = 54.8 bits (126), Expect = 2e-05
Identities = 47/162 (29%), Positives = 72/162 (44%), Gaps = 10/162 (6%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G L + + + + F +DS G LFL KELD + + ++ + V NP
Sbjct: 195 GGKLHFSIAADDKDGHFEVDSSTGDLFLSKELD----YEMMSHYLLRVVTKDHSRNPPVN 250
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG-ENGEFTY--Q 344
+ + + + D ND+ P F +F IS+ EN P G V A D D N Y +
Sbjct: 251 STVFLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFIE 310
Query: 345 LDDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ P F I P SG T+ + LDRE ++ + V A +
Sbjct: 311 ANHPGMNPFLIHPSSG--TLVTTSPLDRERVPTVVLTVTASD 350
Score = 54.4 bits (125), Expect = 2e-05
Identities = 64/246 (26%), Positives = 102/246 (41%), Gaps = 15/246 (6%)
Query: 657 SIVTNATVHVVDVNDERGVLLKG-AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
S T V V D+ND R + A + V E G + + T + G
Sbjct: 34 SATTLVHVSVTDINDNRPYFPQCLAGKELYVKVLE---GQPVNMLVTTVFAKDLDEGNNA 90
Query: 716 VRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
+ +D +D I A G I T + L R+ YRMTVIA ++GV G +
Sbjct: 91 EVIYSVSSEDSSDHFKIDANSGEIRTTRVLSRDYGPSYRMTVIAS-DQGVPPLQGQAVIN 149
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATD-ADEGTNALFMYTLFGEG 833
I + + V I EN K K+ ++IK+ D +++ +
Sbjct: 150 IQVIPLSKGRTVISQNIRHLVIPENLK---PTKVMSLIKSPDHLQRQHGGKLHFSIAADD 206
Query: 834 KE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD---TGGLSSEAELIIMIGDENDN 889
K+ F+VD +TG + F+ LD E Y L +V +D ++S L + + D+ND+
Sbjct: 207 KDGHFEVDSSTGDL-FLSKELDYEMMSHYLLRVVTKDHSRNPPVNSTVFLSVAVEDQNDH 265
Query: 890 KPEFNQ 895
P F +
Sbjct: 266 SPSFRE 271
Score = 54.4 bits (125), Expect = 2e-05
Identities = 79/333 (23%), Positives = 137/333 (41%), Gaps = 74/333 (22%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L+ G +S+ +V++ + DV+DN P F Y+V + E TP G
Sbjct: 1394 LLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKESTPPGS------------ 1441
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
P+ V + A DRD + +++V Y + SGN+ HF LE + L++
Sbjct: 1442 ----PIIV---------VSASDRDVGS--HAEVSYYLTSGNEKQHFCLEEKTGVLSLIKP 1486
Query: 187 ---------VLDYDAGDKE-----FQLVIM-ASGKRIHK-EILFPE-------------- 216
+L A D+E F +V + H + +FP
Sbjct: 1487 LDYEETIKFILTVQASDEERKHFSFAIVFVNVLDDNDHAPQFMFPNLNCAVPENLPVFST 1546
Query: 217 --PIHAIDQDLGVGATLRYELISG--------NDRKLFSLDSVNGSLFLEKELDLDAEHN 266
++A+D D G + Y ++S +D F +D + G + ++ LD + +
Sbjct: 1547 ICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTGDISAQQVLDYEND-- 1604
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
N + L VQA + TA V +++ +++ P F D Y S+ E +
Sbjct: 1605 ---NKYCLIVQAKDKAD--STASVVVWVDVEGIDEFEPIFTQDQYFFSLPEKSHVRHLIG 1659
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
+V A+D D G +G Y L+ P FS++ +G
Sbjct: 1660 RVEASDADAGVDGVILYSLETPSPFFSVNKTNG 1692
Score = 54.0 bits (124), Expect = 3e-05
Identities = 75/293 (25%), Positives = 132/293 (45%), Gaps = 37/293 (12%)
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR-KVL 188
+P G +I I+AF P++ + YS+ SGN+DG F+L S V + K L
Sbjct: 907 VPENCEAGTSIVT-IKAF---APDSIRDSIKYSVFSGNEDGVFSLCSKSGEVTVKEPKFL 962
Query: 189 DYDAGDKEFQLVIMAS--GKRIHKEIL------------FPEPIHAIDQDLG------VG 228
D++ KE QL+++A G++ + ++ F + ++ + G +
Sbjct: 963 DFEV-RKEVQLIVLAESRGRKAYSKVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIV 1021
Query: 229 ATLRYELISGNDRKL-FSLDSVN-GSLFLEKELD--LDAEHNLQ---ANTFVLQVQASQL 281
+L SG++ + +S+ S N G++F L L A L +T+ L VQA
Sbjct: 1022 QVFATDLDSGSNGLVEYSILSGNQGNVFQMDPLSGVLTASAILDYEYTSTYSLIVQAMDK 1081
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
P + ++I++ D+NDN P F + + IVEN G V ++ D D F
Sbjct: 1082 GMPRLSDTTVIKIQVTDINDNAPIF-LPSEAVEIVENSLPGTIVTRISVYDVDSNPAFTF 1140
Query: 342 TYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
++ + G F+ID +G + V +T LD E + +++ + GT
Sbjct: 1141 SFVKESNSGTKFAIDRNTG-VVVLVET-LDFEEATKYELQIQISDLVHQTEGT 1191
Score = 52.8 bits (121), Expect = 7e-05
Identities = 48/171 (28%), Positives = 79/171 (46%), Gaps = 23/171 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GTT++ L++ D D GLNGQ Y E S+ A F I+ G
Sbjct: 701 VREDAQVGTTVLVLSSADEDEGLNGQTMYSLVHE--------SSGA------FTIDPVAG 746
Query: 1000 HVIVARSLPPE--SEFRLNISALD---GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ +R+L E SE L A D G+ + + ++V V DVND+ PV ++ + +
Sbjct: 747 TLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVLEQNPLDIFL 806
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSV 1104
T + + A+D D G N +T+ F +P I+ TG + +
Sbjct: 807 SSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSV---LSINEYTGAIQL 854
Score = 47.2 bits (107), Expect = 0.003
Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYN----FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
V V V D+ND+ P F + V E Q ++ V A D D G NA + Y +
Sbjct: 39 VHVSVTDINDNRPYFPQCLAGKELYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSVSS 98
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D+ F+I +G + L R+ Y +TV+A D G
Sbjct: 99 EDSSDHFKIDANSGEIRTTRVLSRDYGPSYRMTVIASDQG 138
Score = 42.3 bits (95), Expect = 0.099
Identities = 18/43 (41%), Positives = 27/43 (62%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDA 1483
+ D D G+N Y +++E + F IDPV+GT+R AL R+A
Sbjct: 716 SADEDEGLNGQTMYSLVHESSGAFTIDPVAGTLRTSRALDREA 758
Score = 41.9 bits (94), Expect = 0.13
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F + +G+L LD + + + + L++ A+V I LD+ND+
Sbjct: 319 FLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAKVVI--LDVNDHS 376
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P F F + E+ G V + A D D G NG T+ + + AF +D SG+L
Sbjct: 377 PTF-TSFPIAHVREDAAVGSLVHHITAQDPDAGRNGRVTFSILSGNENMAFMLDESSGFL 435
Query: 362 TVRNQTVLDREAHS 375
T + LD E S
Sbjct: 436 TTASP--LDYEIKS 447
Score = 41.1 bits (92), Expect = 0.23
Identities = 47/177 (26%), Positives = 77/177 (43%), Gaps = 16/177 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + +LD +DN P F S Y +K + G+ I V A D D+G + V Y
Sbjct: 1404 LSSSATVSIEVLDVDDNPPAF-SSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYY 1462
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
L TS F + TG +S+ + E + L V+ASD+ + +S A+V
Sbjct: 1463 L--TSG-NEKQHFCLEEKTGVLSLIKPLDYEETIKFILTVQASDE----ERKHFSFAIVF 1515
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
+ V + P FM V N+ + +++ + DA D++Y ++
Sbjct: 1516 VNVL----DDNDHAPQFMFPNLNCAVPENLPVFSTICSVNALDFDAGPYGDMTYSIV 1568
Score = 39.9 bits (89), Expect = 0.53
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V + ++ P+F Y FS+ + V +IG+V+A D D G +G++LY L+
Sbjct: 1623 VVVWVDVEGIDEFEPIFTQDQ-YFFSLPEKSHVRHLIGRVEASDADAGVDGVILYSLETP 1681
Query: 503 SNLTITSPFKINPNTGTVSVAES-PILEGR 531
S F +N G + ++ + P+++ +
Sbjct: 1682 SPF-----FSVNKTNGNIYLSRALPLIKSQ 1706
Score = 35.9 bits (79), Expect = 8.6
Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 24/156 (15%)
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE---HYE 1286
P ++ST L V V D D P F + + + EN + N + +
Sbjct: 247 PPVNSTVFLSVAVEDQNDH-----SPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFL 301
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N +++Y+I E + F+I P +GTL DRE T + V A Q +
Sbjct: 302 NSRIQYFI--EANHPGMNPFLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVN----- 354
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
V + L + KVV I DVND+SP FT+
Sbjct: 355 ----VTDRRLRSLM---AKVV--ILDVNDHSPTFTS 381
>UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11;
Clupeocephala|Rep: Protocadherin2-gamma-v5-sCP1 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 969
Score = 114 bits (275), Expect = 2e-23
Identities = 127/462 (27%), Positives = 189/462 (40%), Gaps = 33/462 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN P+F P + NA +G +A+D D+G NG+ Y L T N
Sbjct: 130 VTVEVQDINDNAPLF-PKESVNLEISENAVLGARFPLDRAMDTDVGLNGIQSYKLHPTDN 188
Query: 505 LTITSPFKINPNTGTVSVAESPI-LEGRHAL-FVEASDQPANPSERRYSLAVVTIEVTRG 562
+ + N + + + E R + V + +P + V I VT
Sbjct: 189 FKLEVHSLTDGNKYIEMILQRELDREERDEIKLVLLATDGGSPQKS----GTVKIHVT-- 242
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL-LHGYEEGVP 619
+ P + ++ V N GT +G + DA E VSY L EE
Sbjct: 243 ILDANDNAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYFALANKEEREL 302
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F + +G +T++ L ++ Y A ++ LS + V D ND +
Sbjct: 303 FNINSETGEVTLLAHLDYESQNSYQLNINA-RDKGGLSDTCKIVIDVTDENDNPPTIQLM 361
Query: 680 AHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ S I ENS G + I N+ G V F I + +E ++
Sbjct: 362 SFSNTI---AENSPVGTTVAVI---NVEDADSGKNGLVHFSINQNIPFKIESTFSEYYSL 415
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T LDRE Y +T++ ++G + + + I D NDNPP F Y+ F+ E
Sbjct: 416 ITDDMLDRETVTEYNITILVS-DQGSPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNE 474
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENTGVVKFIGDS 852
N+ G I +KA DAD G NA Y L E + VD TG V + S
Sbjct: 475 NNSPGVTIL---TVKANDADWGPNAQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAV-KS 530
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
D E+ + ++ ARD G LSSE + I I D+NDN P+
Sbjct: 531 FDFEQLKSFSFNVTARDGGSPPLSSEVTITINIQDQNDNAPQ 572
Score = 105 bits (251), Expect = 1e-20
Identities = 122/498 (24%), Positives = 206/498 (41%), Gaps = 66/498 (13%)
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIA 721
TV V D+ND + K + + + EN A +G F + + G ++ + +
Sbjct: 131 TVEVQDINDNAPLFPKES---VNLEISEN---AVLGARFPLDRAMDTDVGLNGIQSYKLH 184
Query: 722 NQQDVTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ ++ DG + Q+ LDRE+RD ++ ++A + G +G ++ + I
Sbjct: 185 PTDNFKLEVHSLTDGNKYIEMILQRELDREERDEIKLVLLAT-DGGSPQKSGTVKIHVTI 243
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF 837
D NDN PV + + ++ + ENS GT + + A DADEG N
Sbjct: 244 LDANDNAPVCKQSVFKTEVRENSPAGTVM---GTVSAADADEGVN--------------- 285
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
G V + ++E++ ++ ++ +TG E L+ + E+ N + N I
Sbjct: 286 ------GHVSYYFALANKEERELFNIN---SETG----EVTLLAHLDYESQNSYQLN-IN 331
Query: 898 ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALD 957
K + K+ +I+V +N + + I EN P+GTT+ +N D
Sbjct: 332 ARDKGGLSDTCKI-------VIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVINVED 384
Query: 958 LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI 1017
DSG NG + + N + P K+ + E Y +I + ++ R E + +
Sbjct: 385 ADSGKNGLVHFSINQNI---PFKIESTFSEY--YSLITDD----MLDRETVTEYNITILV 435
Query: 1018 SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
S + N ++ V + DVND+ P F Y V E + V A DAD+G N
Sbjct: 436 SDQGSPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPN 495
Query: 1078 ANLTYFIQPSD-TDLPF----EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
A L+YF++ D P + LTG + D E + V ARD G
Sbjct: 496 AQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAVKSFDFEQLKSFSFNVTARDGG-SPPLS 554
Query: 1133 XXXXXXXXXXDVNDNSPK 1150
D NDN+P+
Sbjct: 555 SEVTITINIQDQNDNAPQ 572
Score = 96.3 bits (229), Expect = 6e-18
Identities = 126/467 (26%), Positives = 198/467 (42%), Gaps = 51/467 (10%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V ++D ND V + V+ENS AG +G + + NG + F +AN
Sbjct: 241 VTILDANDNAPVCKQSVFKT---EVRENSPAGTVMGTVSAADADEGV-NGHVSYYFALAN 296
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+++ +E G + LD E ++ Y++ + A +KG +S ++ I + DEND
Sbjct: 297 KEERELFNINSETGEVTLLAHLDYESQNSYQLNINAR-DKGGLSDT--CKIVIDVTDEND 353
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
NPP + ++ I ENS +GT + + N+ DAD G N L +++ + +
Sbjct: 354 NPPTIQLMSFSNTIAENSPVGTTVAVINV---EDADSGKNGLVHFSINQNIPFKIESTFS 410
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEENS 900
D LDRE Y ++++ D G + S L + I D NDN P+F E +
Sbjct: 411 EYYSLITDDMLDRETVTEYNITILVSDQGSPARHSNKTLNVKISDVNDNPPKFGSDEYKT 470
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
V N + G TI+ VK + QL FL E+I G + L ++D
Sbjct: 471 FV------NENNSPGVTILTVKANDADWGPNAQLS-YFLKDEDIR-GAPLSSLVSVD--- 519
Query: 961 GLNGQIRYEFNSEVYIPPSKLSADALEVKRY-FVINERHGHVIVARSLPPESEFRLNISA 1019
L G + + S D ++K + F + R G S P SE + I+
Sbjct: 520 ALTGTVH-----------AVKSFDFEQLKSFSFNVTARDG-----GSPPLSSEVTITINI 563
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
D NDN ++ V V + V A ++ KV A D D GQNA
Sbjct: 564 QD---QNDNAPQVLY--PVQTGASVVAEI-----VPRAVDVGYLVTKVVAVDVDSGQNAW 613
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
L+Y +Q + FE+ G + ++ + K LTVV DNG
Sbjct: 614 LSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNG 660
Score = 95.1 bits (226), Expect = 1e-17
Identities = 133/532 (25%), Positives = 223/532 (41%), Gaps = 64/532 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN +G A+D D GLNG Y+ + P LEV ++
Sbjct: 153 ISENAVLGARFPLDRAMDTDVGLNGIQSYKLH-----PTDNFK---LEVHS-LTDGNKYI 203
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+I+ R L E E +L + A DGG+ + + + V + D ND+ PV K++ + V
Sbjct: 204 EMILQRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVR 263
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETE 1113
E V+G V A DAD G N +++Y+ ++ + F I+ TG +++ LD E++
Sbjct: 264 ENSPAGTVMGTVSAADADEGVNGHVSYYFALANKEERELFNINSETGEVTLLAHLDYESQ 323
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP--KFYAFDELLEWKHPEADELSNH 1171
+ Y L + ARD G D NDN P + +F + P ++
Sbjct: 324 NSYQLNINARDKG---GLSDTCKIVIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVI 380
Query: 1172 NFESV--MMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
N E + +I +N P I +T ++ ++ TD + + + Y++ + Q
Sbjct: 381 NVEDADSGKNGLVHFSINQNIPFKIESTFSEYYSLITDDMLDRETVTEYNITILVSDQ-- 438
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP---VELVSLNLTEH 1284
G P+ S L V ++DV D + P F S Y+ + EN N+P + V N +
Sbjct: 439 GSPARHSNKTLNVKISDVND-----NPPKFGSDEYKTFVNEN-NSPGVTILTVKANDADW 492
Query: 1285 YENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
N ++ Y++ +E+ + +D GT++ V+S D E ++ V A R S
Sbjct: 493 GPNAQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAVKSFDFEQLKSFSFNVTA-RDGGSP 551
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK----FTNGNRPLVTAIPTTAPFG 1398
L +V + + I+D NDN+P+ G + +P G
Sbjct: 552 PL----------------SSEVTITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVG 595
Query: 1399 YQVMQLKGA---IGHHPTASRTVRADTDELVFFERLSLNG--LTSPQATDSD 1445
Y V ++ G + S ++ D +F L NG T Q TD D
Sbjct: 596 YLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQ-NGEIRTVRQVTDKD 646
Score = 89.8 bits (213), Expect = 5e-16
Identities = 115/464 (24%), Positives = 195/464 (42%), Gaps = 34/464 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + VT+LDANDN PV S +++ ++ N+ GTV+G V A D D G NG V Y
Sbjct: 237 VKIHVTILDANDNAPVCKQS-VFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYF-AL 294
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+N F IN TG V++ E +++ + + A + I+VT
Sbjct: 295 ANKEERELFNINSETGEVTLLAHLDYESQNSYQLNIN---ARDKGGLSDTCKIVIDVT-- 349
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH-GYEEGVPFA 621
+ + P P + + N +GT+V I V DA + L+H + +PF
Sbjct: 350 DENDNP--PTIQLMSFSNTIAENSPVGTTVAVINVEDA---DSGKNGLVHFSINQNIPFK 404
Query: 622 VEER-SGVITVVDD--LSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDERGVL 676
+E S +++ D L R Y+ + + + + + +N T V + DVND
Sbjct: 405 IESTFSEYYSLITDDMLDRETVTEYNI-TILVSDQGSPARHSNKTLNVKISDVNDNPPKF 463
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ---QDVTDDIAI- 732
G+ F + NS G I + + +G FL ++ +++
Sbjct: 464 --GSDEYKTFVNENNSPGVTILTVKANDAD--WGPNAQLSYFLKDEDIRGAPLSSLVSVD 519
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A GT+ K D E+ + V A + G + +TI I+D+NDN P +
Sbjct: 520 ALTGTVHAVKSFDFEQLKSFSFNVTAR-DGGSPPLSSEVTITINIQDQNDNAPQVLYPVQ 578
Query: 793 EGFIMENSKIGTEIKMDNIIK---ATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKF 848
G + + + + ++ A D D G NA Y L + +F+V G ++
Sbjct: 579 TGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRT 638
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
+ D++ + KL++V D G S A + I + D+ PE
Sbjct: 639 VRQVTDKD-AVKQKLTVVVEDNGQPSRSAVVSINVA-VADSFPE 680
Score = 66.5 bits (155), Expect = 5e-09
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 9/176 (5%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ GT+ ++ +DRE+ F+ V + +++VT+ ++D NDN P+F +
Sbjct: 91 DKGTLVVKERIDREELCKQTTPCSFSFDLIVENPIQLHRVTVEVQDINDNAPLFPKESVN 150
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKFI 849
I EN+ +G +D +A D D G N + Y L +V D N + +
Sbjct: 151 LEISENAVLGARFPLD---RAMDTDVGLNGIQSYKLHPTDNFKLEVHSLTDGNKYIEMIL 207
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
LDRE++ KL L+A D G S ++ + I D NDN P Q ++VR
Sbjct: 208 QRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVR 263
Score = 64.9 bits (151), Expect = 2e-08
Identities = 42/170 (24%), Positives = 84/170 (49%), Gaps = 7/170 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D+G+ Y+L ++ KL +G+ ++E L + + + + L + A+
Sbjct: 168 AMDTDVGLNGIQSYKLHPTDNFKLEVHSLTDGNKYIEMILQRELDRE-ERDEIKLVLLAT 226
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P K+ ++ + +LD NDN P + + + EN P G + V A D D+G NG
Sbjct: 227 DGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNG 286
Query: 340 EFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+Y + + F+I+ +G +T+ LD E+ +S ++ + A++
Sbjct: 287 HVSYYFALANKEERELFNINSETGEVTLLAH--LDYESQNSYQLNINARD 334
Score = 58.0 bits (134), Expect = 2e-06
Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 11/171 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGN--DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D GV + Y N +R+LF+++S G + L LD +++ N++ L
Sbjct: 275 VSAADADEGVNGHVSYYFALANKEERELFNINSETGEVTLLAHLDYESQ-----NSYQLN 329
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A T ++ I++ D NDN P ++ ++ +I EN P G +V + D D
Sbjct: 330 INARDKGGLSDTC--KIVIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVINVEDADS 387
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+NG + ++ F I+ S + ++ +LDRE + + + +
Sbjct: 388 GKNGLVHFSINQ-NIPFKIESTFSEYYSLITDDMLDRETVTEYNITILVSD 437
Score = 54.4 bits (125), Expect = 2e-05
Identities = 72/332 (21%), Positives = 128/332 (38%), Gaps = 20/332 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L+ G Q S + + V I D NDN P+ + + V E +P G A
Sbjct: 223 LLATDGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVRENSPAGTVMGTVSAADADE 282
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL--LL 184
+ ++ L ++ F+ + + + + + + + K L
Sbjct: 283 GVNGHVSYYFALANKEERELFNINSETGEVTLLAHLDYESQNSYQLNINARDKGGLSDTC 342
Query: 185 RKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGND 240
+ V+D D D + +M+ I + + I D D G + + +
Sbjct: 343 KIVIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVINVEDADSGKNGLVHFSINQNIP 402
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
K+ S S SL + LD + + + + S +P + + + +++ D+N
Sbjct: 403 FKIESTFSEYYSLITDDMLDRET-----VTEYNITILVSDQGSPARHSNKTLNVKISDVN 457
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGA-----FS 353
DN P+F D Y + EN G ++L V A D D G N + +Y L +D +GA S
Sbjct: 458 DNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPNAQLSYFLKDEDIRGAPLSSLVS 517
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+D +G TV D E S V A++
Sbjct: 518 VDALTG--TVHAVKSFDFEQLKSFSFNVTARD 547
Score = 53.6 bits (123), Expect = 4e-05
Identities = 58/228 (25%), Positives = 93/228 (40%), Gaps = 14/228 (6%)
Query: 927 FALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
+ +DV + IPE +P G+ + + A DL ++ I + + V + D
Sbjct: 33 YGMDVVYCNVRYSIPEEMPEGSFVGNI-AKDLGIEISRLISGK--ARVVTKSGRQYVDLS 89
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
K V+ ER + + P S F ++ + L+ V V V+D+ND+ P+F
Sbjct: 90 RDKGTLVVKERIDREELCKQTTPCS-FSFDLIVENPIQLH---RVTVEVQDINDNAPLFP 145
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-----V 1101
K N + E A D D G N +Y + P+D + E+ LT
Sbjct: 146 KESVNLEISENAVLGARFPLDRAMDTDVGLNGIQSYKLHPTD-NFKLEVHSLTDGNKYIE 204
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ + ELDRE D+ L ++A D G D NDN+P
Sbjct: 205 MILQRELDREERDEIKLVLLATDGG-SPQKSGTVKIHVTILDANDNAP 251
Score = 49.6 bits (113), Expect = 6e-04
Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 19/167 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR-----KLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D G A L Y L + R L S+D++ G++ K D + Q +F
Sbjct: 485 VKANDADWGPNAQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAVKSFDFE-----QLKSF 539
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN----GFSVL 326
V A +P +++ + I + D NDN P+ + V + E +P G+ V
Sbjct: 540 SFNVTARDGGSPPLSSEVTITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVT 599
Query: 327 QVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWL-TVRNQTVLD 370
+V+A D D G+N +Y+L + F + ++G + TVR T D
Sbjct: 600 KVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKD 646
Score = 44.8 bits (101), Expect = 0.018
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ NP++ RV +E+ D+NDN P F + N+ I EN G A D D G NG
Sbjct: 121 VENPIQLH--RVTVEVQDINDNAPLFPKESVNLEISENAVLGARFPLDRAMDTDVGLNGI 178
Query: 341 FTYQLDDPKGAFSIDPRS-----GWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
+Y+L P F ++ S ++ + Q LDRE +++ + A + +P GT
Sbjct: 179 QSYKL-HPTDNFKLEVHSLTDGNKYIEMILQRELDREERDEIKLVLLATDGGSPQKSGT 236
Score = 41.5 bits (93), Expect = 0.17
Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V + + + D NDN P V P +++ + VG ++ KV AVD D GQN
Sbjct: 553 LSSEVTITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNA 612
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ Y LQ+ + + N TV V + ++ + + VE + QP+ + ++
Sbjct: 613 WLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINV 672
Query: 553 AV 554
AV
Sbjct: 673 AV 674
>UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysia
californica|Rep: Cadherin-like protein cad2 - Aplysia
californica (California sea hare)
Length = 736
Score = 114 bits (275), Expect = 2e-23
Identities = 124/489 (25%), Positives = 211/489 (43%), Gaps = 34/489 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L S + VE+ ++ ND+ P F+ S F + + +VG +I +KA +G V
Sbjct: 42 EPSLESHIPVEILVMGRNDSPPKFLESRR-PFFVDEDEQVGAIIATIKA-----RSSGPV 95
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ LQ + S + P TV L R S + ++ R S A+V
Sbjct: 96 V--LQHCTRFH--SKCQNKPAIFTVDSLGRLRLMRRLDWETTPSYRLFVRAQSRTSPALV 151
Query: 556 T-IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHG 613
+E+ + + P F PY+ V + + Q++ +D + N + + L G
Sbjct: 152 DHMEIGIEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNPLKFTLGPG 211
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAV-------ALQENA---NLSIVTNA 662
+ F+++ +SG I ++ L R + Y+ V +L+++ +L+ T+
Sbjct: 212 MQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSV 271
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ V D ND K + + + GA G + T ++ +G +
Sbjct: 272 LITVTDCNDNPPAFEKQNYPTAV------NEGALPGTVLITLDTTDADSGPNSDVTYYIT 325
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ D I G +F KPLDRE + YR+ V A V VT+ + D+ND
Sbjct: 326 EGDQLGRFEIHSTGELFVNKPLDRETKAQYRLRVAATDGAYVT----FTTVTVDVLDDND 381
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
N PV + F M+ S I I+ DA N+ Y+L GEG + F +D+
Sbjct: 382 NAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSYSLTGEGADHFLIDKE 441
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
TG+++ LDRE + ++L+ VARD GGLS ++I + D DN P F Q
Sbjct: 442 TGLIR-TAKLLDRETQPEFELTAVARDGGGLSCTTLVLIYLKDVXDNAPTFTQGTLRKLY 500
Query: 903 RIHRETKLN 911
IH + +++
Sbjct: 501 SIHEDAEIH 509
Score = 113 bits (271), Expect = 5e-23
Identities = 128/467 (27%), Positives = 208/467 (44%), Gaps = 37/467 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +V +T+ D NDN P F N Y ++ A GTV+ + D D G N V Y
Sbjct: 265 LTTTTSVLITVTDCNDNPPAFEKQN-YPTAVNEGALPGTVLITLDTTDADSGPNSDVTYY 323
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVV 555
+ L F+I+ +TG + V P+ + ++ L V A+D + V
Sbjct: 324 ITEGDQL---GRFEIH-STGELFV-NKPLDRETKAQYRLRVAATDGAY------VTFTTV 372
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHG 613
T++V I F+ + S V IR DA + VSY L
Sbjct: 373 TVDVLDDNDNAPVCISRFIKW-FRMKTSSKALPIAHVRGIRDADAPSTVNSRVSYSLTG- 430
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
E F +++ +G+I L R +P ++ AVA ++ LS T +++ DV D
Sbjct: 431 -EGADHFLIDKETGLIRTAKLLDRETQPEFELTAVA-RDGGGLSCTTLVLIYLKDVXDNA 488
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAI 732
+G + + + E+ A I + ++ G + +R+ A +D + +I
Sbjct: 489 PTFTQGTLRKL-YSIHED---AEIHTLXIRLVAIDTDTGINSQIRYRXA--RDXINTFSI 542
Query: 733 AED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
D G + L RE+ Y +TV+A +N + + + + D NDNPP F+H++
Sbjct: 543 HPDSGIVSLIAALGRERNPSYNLTVVA-YNPISPTSPRKLTIMVTVLDVNDNPPEFQHSS 601
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIG 850
Y I E++ +GT I I AT D G NA Y++ G + F +D N GV+ +
Sbjct: 602 YYATIQESANVGTPI---IXITATSLDIGXNADITYSIAAGNEQGKFSIDPNKGVL-VVT 657
Query: 851 DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ LD E Y ++++A D G L+ A + I I D NDN P F+Q
Sbjct: 658 EPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQ 704
Score = 97.5 bits (232), Expect = 2e-18
Identities = 123/466 (26%), Positives = 199/466 (42%), Gaps = 29/466 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L+ + + + + D NDN P F Y+ ++ +AK I +++A D DL Q + +
Sbjct: 150 LVDHMEIGIEVRDVNDNPPFFA-CMPYQATVSESAKSQHQIIQLQASDRDL-QTNPLKFT 207
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSER--RYSLAV 554
L + S F I+ +G + + E ++ L V SD P++ + +Y
Sbjct: 208 L-GPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLT 266
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
T V + P F Y V GT + + DA +DV+Y +
Sbjct: 267 TTTSVLITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITE 326
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G + G F + +G + V L R + Y VA + A ++ T TV V+D ND
Sbjct: 327 GDQLG-RFEIHS-TGELFVNKPLDRETKAQYRLR-VAATDGAYVTF-TTVTVDVLDDNDN 382
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V + + F +K +S I + + T N R + + D I
Sbjct: 383 APVCI--SRFIKWFRMKTSSKALPIAHV--RGIRDADAPSTVNSRVSYSLTGEGADHFLI 438
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
E G I T K LDRE + + +T +A + G +S + V IY++D DN P F T
Sbjct: 439 DKETGLIRTAKLLDRETQPEFELTAVAR-DGGGLSCTTL--VLIYLKDVXDNAPTFTQGT 495
Query: 792 YEGF--IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
I E+++I T + + A D D G N+ Y + F + ++G+V I
Sbjct: 496 LRKLYSIHEDAEIHT---LXIRLVAIDTDTGINSQIRYRXARDXINTFSIHPDSGIVSLI 552
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEF 893
+L RE+ Y L++VA + +S +L IM+ D NDN PEF
Sbjct: 553 A-ALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEF 597
Score = 88.2 bits (209), Expect = 2e-15
Identities = 67/222 (30%), Positives = 102/222 (45%), Gaps = 19/222 (8%)
Query: 934 LGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
L L+ I E+ I T I+L A+D D+G+N QIRY + + D + F
Sbjct: 496 LRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRY-----------RXARDXINT---FS 541
Query: 994 INERHGHVIVARSLPPESEFRLNISALDGGNLNDN----ISVRVFVKDVNDHFPVFKKTW 1049
I+ G V + +L E N++ + ++ +++ V V DVND+ P F+ +
Sbjct: 542 IHPDSGIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEFQHSS 601
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y ++E+ + + AT D G NA++TY I + F I P GVL V LD
Sbjct: 602 YYATIQESANVGTPIIXITATSLDIGXNADITYSIAAGNEQGKFSIDPNKGVLVVTEPLD 661
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E +Y +TV+A D G DVNDN P+F
Sbjct: 662 HELAREYFITVLATDRG-TPPLTDTAIVSINITDVNDNPPRF 702
Score = 83.0 bits (196), Expect = 6e-14
Identities = 100/369 (27%), Positives = 151/369 (40%), Gaps = 39/369 (10%)
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+L SV + V D ND+ P F+K Y V E VL +D TDAD G N+++TY+
Sbjct: 264 SLTTTTSVLITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYY 323
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
I D FEI TG L VN LDRET+ +Y L V A D D
Sbjct: 324 ITEGDQLGRFEIHS-TGELFVNKPLDRETKAQYRLRVAATDG----AYVTFTTVTVDVLD 378
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
NDN+P ++W + + V I A N+ + ++ A D
Sbjct: 379 DNDNAP--VCISRFIKWFRMKTSSKA-LPIAHVRGIRDADAPSTVNSRVSYSLTGEGA-D 434
Query: 1204 TDFIGNGNGLI-LYSLPQRKNQQNLGLPS-------LSSTAILMVTVADVPDEVEMSDKP 1255
I GLI L R+ Q L + LS T ++++ + DV D +
Sbjct: 435 HFLIDKETGLIRTAKLLDRETQPEFELTAVARDGGGLSCTTLVLIYLKDVXDNAPTFTQG 494
Query: 1256 VFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
Y E E + LV+++ T+ N ++RY D TF I P +G +
Sbjct: 495 TLRKLYSIHEDAEIHTLXIRLVAID-TDTGINSQIRY----RXARDXINTFSIHPDSGIV 549
Query: 1316 YLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVND 1375
L+ + RE +Y + V VA + + + + ++V + DVND
Sbjct: 550 SLIAALGRERNPSYNLTV-----------------VAYNPISPTSPRKLTIMVTVLDVND 592
Query: 1376 NSPKFTNGN 1384
N P+F + +
Sbjct: 593 NPPEFQHSS 601
Score = 71.7 bits (168), Expect = 1e-10
Identities = 67/271 (24%), Positives = 121/271 (44%), Gaps = 21/271 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYE-FSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
V + L D DN P F L + +S+ +A++ T+ ++ A+D D G N + Y R
Sbjct: 477 VLIYLKDVXDNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRYRXARDX 536
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ F I+P++G VS+ + E + L V A + + S R+ ++ V ++V
Sbjct: 537 ----INTFSIHPDSGIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDV-- 590
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVP 619
+ P P+F + Y + + +GT + I D D++Y + G E+G
Sbjct: 591 ---NDNP--PEFQHSSYYATIQESANVGTPIIXITATSLDIGXNADITYSIAAGNEQG-K 644
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
F+++ GV+ V + L Y +A L+ ++++ DVND +
Sbjct: 645 FSIDPNKGVLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQ 704
Query: 679 GAHSPIIFHVKEN-SAGAAIGQIFHTNMSSI 708
A P+ HVK N G I ++ T+ S+
Sbjct: 705 DALPPV--HVKXNVHEGTXIFKVMATDXDSL 733
Score = 68.9 bits (161), Expect = 1e-09
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Query: 991 YFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
+F+I++ G + A+ L E+ EF L A DGG L+ V +++KDV D+ P F +
Sbjct: 435 HFLIDKETGLIRTAKLLDRETQPEFELTAVARDGGGLSCTTLVLIYLKDVXDNAPTFTQG 494
Query: 1049 WYN--FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+++ E + ++ A D D G N+ + Y D F I P +G++S+
Sbjct: 495 TLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRY-RXARDXINTFSIHPDSGIVSLIA 553
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L RE Y LTVVA N DVNDN P+F
Sbjct: 554 ALGRERNPSYNLTVVAY-NPISPTSPRKLTIMVTVLDVNDNPPEF 597
Score = 65.7 bits (153), Expect = 9e-09
Identities = 47/146 (32%), Positives = 71/146 (48%), Gaps = 8/146 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D G+ + +RY + + FS+ +G + L L E N N L V A
Sbjct: 517 AIDTDTGINSQIRYRX-ARDXINTFSIHPDSGIVSLIAALG--RERNPSYN---LTVVAY 570
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P + + + +LD+NDN PEF+ Y +I E+ G ++ + AT D G N
Sbjct: 571 NPISPTSPRKLTIMVTVLDVNDNPPEFQHSSYYATIQESANVGTPIIXITATSLDIGXNA 630
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTV 363
+ TY + + +G FSIDP G L V
Sbjct: 631 DITYSIAAGNEQGKFSIDPNKGVLVV 656
Score = 63.7 bits (148), Expect = 4e-08
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D+G A + Y + +GN++ FS+D G L + + LD H L A + + V
Sbjct: 619 ITATSLDIGXNADITYSIAAGNEQGKFSIDPNKGVLVVTEPLD----HEL-AREYFITVL 673
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVD-FYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P T A V I + D+NDN P F D + + N+ G + +VMATD D
Sbjct: 674 ATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHVKXNVHEGTXIFKVMATDXDSL 733
Query: 337 EN 338
N
Sbjct: 734 AN 735
Score = 62.5 bits (145), Expect = 9e-08
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 16/197 (8%)
Query: 197 FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLF 254
+Q + S K H+ I + A D+DL L++ L G +FS+D+ +G +
Sbjct: 175 YQATVSESAKSQHQII----QLQASDRDLQTNP-LKFTLGPGMQAMASIFSIDAKSGWIM 229
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNN----PLKTAQARVEIELLDLNDNLPEFEVDF 310
L +LD + + V +S L P T V I + D NDN P FE
Sbjct: 230 LLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFEKQN 289
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
Y ++ E G ++ + TD D G N + TY + D G F I +G L V
Sbjct: 290 YPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIH-STGELFVNKP-- 346
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE + R++V A +
Sbjct: 347 LDRETKAQYRLRVAATD 363
Score = 59.3 bits (137), Expect = 8e-07
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 11/154 (7%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
N +F++DS+ G L L + LD + ++ L V+A +P + IE+ D
Sbjct: 109 NKPAIFTVDSL-GRLRLMRRLDWET-----TPSYRLFVRAQSRTSPALVDHMEIGIEVRD 162
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTY--QLDDPKGAFSID 355
+NDN P F Y ++ E+ + ++Q+ A+D+D N +FT + FSID
Sbjct: 163 VNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNPLKFTLGPGMQAMASIFSID 222
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
+SGW+ + T LDRE S + V ++ S
Sbjct: 223 AKSGWIML--LTKLDRETQSQYNLTVVVSDSPSS 254
Score = 56.0 bits (129), Expect = 7e-06
Identities = 55/198 (27%), Positives = 94/198 (47%), Gaps = 25/198 (12%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + LD E YR+ V A+ ++ + ++ I + D NDNPP F Y+
Sbjct: 120 GRLRLMRRLDWETTPSYRLFVRAQ-SRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQAT 178
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGD 851
+ E++K +I ++A+D D TN L +TL G G + +F +D +G + +
Sbjct: 179 VSESAKSQHQIIQ---LQASDRDLQTNPL-KFTL-GPGMQAMASIFSIDAKSGWIMLL-T 232
Query: 852 SLDREKKIMYKLSLVARDT-----------GGLSSEAELIIMIGDENDNKPEFNQIEENS 900
LDRE + Y L++V D+ L++ ++I + D NDN P F ++N
Sbjct: 233 KLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFE--KQNY 290
Query: 901 KVRIHRETKLNGTAGFTI 918
++ E L GT T+
Sbjct: 291 PTAVN-EGALPGTVLITL 307
Score = 53.6 bits (123), Expect = 4e-05
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 14/160 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ + VT+LD NDN P F S+ Y +++ +A VGT I + A D+G N + Y +
Sbjct: 581 LTIMVTVLDVNDNPPEFQHSSYYA-TIQESANVGTPIIXITATSLDIGXNADITYSIAAG 639
Query: 503 SNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ F I+PN G + V E P+ L + + V A+D+ P A+V+I +
Sbjct: 640 NE---QGKFSIDPNKGVLVVTE-PLDHELAREYFITVLATDRGTPPLT---DTAIVSINI 692
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
T N P P V NV GT + ++ D
Sbjct: 693 T-DVNDNPPRFSQDALPPVH--VKXNVHEGTXIFKVMATD 729
Score = 53.2 bits (122), Expect = 5e-05
Identities = 87/379 (22%), Positives = 147/379 (38%), Gaps = 54/379 (14%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
L D++ + + V+DVND+ P F Y V E+ ++ + ++ A+D D N L + +
Sbjct: 150 LVDHMEIGIEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNP-LKFTL 208
Query: 1085 QPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARD--------NGXXXXXXXX 1134
P + F I +G + + +LDRET+ +Y LTVV D +G
Sbjct: 209 GPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTT 268
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
D NDN P F + +P A ++ ++I + T ++ P
Sbjct: 269 TSVLITVTDCNDNPPAFE------KQNYPTA--VNEGALPGTVLITL-DTTDADSGPNSD 319
Query: 1195 TVAKVFANDT--DFIGNGNGLILYSLP---QRKNQQNLGLPSLSSTAILMVTV-ADVPDE 1248
+ D F + G + + P + K Q L + + + TV DV D+
Sbjct: 320 VTYYITEGDQLGRFEIHSTGELFVNKPLDRETKAQYRLRVAATDGAYVTFTTVTVDVLDD 379
Query: 1249 VEMSDKPVFISRY---YELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNENDTDIRR 1304
+ + PV ISR+ + ++ + + + R Y L D
Sbjct: 380 ND--NAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSYSLTGEGAD--- 434
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
F+ID G + + DRE + +E+ VA D G
Sbjct: 435 HFLIDKETGLIRTAKLLDRETQPEFELTA-----------------VARD--GGGLSCTT 475
Query: 1365 KVVVRIKDVNDNSPKFTNG 1383
V++ +KDV DN+P FT G
Sbjct: 476 LVLIYLKDVXDNAPTFTQG 494
Score = 47.6 bits (108), Expect = 0.003
Identities = 86/373 (23%), Positives = 145/373 (38%), Gaps = 30/373 (8%)
Query: 988 VKRYFVINERHGHVIVARSL-PPESE-FRLNISALDGG--NLNDNISVRVFVKDVNDHFP 1043
V++ F +N G ++ SL E++ F+ + A DGG +L +I V + V ND P
Sbjct: 4 VEKLFDVNAYSGEIVPRDSLIDAENQLFQFFVRAADGGEPSLESHIPVEILVMGRNDSPP 63
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
F ++ F V+E + ++ + A + + T F G L
Sbjct: 64 KFLESRRPFFVDEDEQVGAIIATIKARSSGPVVLQHCTRFHSKCQNKPAIFTVDSLGRLR 123
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF------DEL 1157
+ LD ET Y L V A+ DVNDN P F E
Sbjct: 124 LMRRLDWETTPSYRLFVRAQSR-TSPALVDHMEIGIEVRDVNDNPPFFACMPYQATVSES 182
Query: 1158 LEWKHPEAD-ELSNHNFESVMMIPVYKATIEENAPIGTTVAK------VFANDTDFIGNG 1210
+ +H + S+ + ++ + ++ A I + AK + D +
Sbjct: 183 AKSQHQIIQLQASDRDLQTNPLKFTLGPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQY 242
Query: 1211 NGLILYS-LPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
N ++ S P +++ PSL++T +++TV D D + P F + Y + E
Sbjct: 243 NLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCND-----NPPAFEKQNYPTAVNEG 297
Query: 1270 VNAPVELVSLNLT--EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
L++L+ T + N + YYI + D F I G L++ + DRE K
Sbjct: 298 ALPGTVLITLDTTDADSGPNSDVTYYI---TEGDQLGRFEIH-STGELFVNKPLDRETKA 353
Query: 1328 TYEVIVRAERQKY 1340
Y + V A Y
Sbjct: 354 QYRLRVAATDGAY 366
Score = 41.5 bits (93), Expect = 0.17
Identities = 19/42 (45%), Positives = 27/42 (64%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
A D+D GIN+ IRY+ + F+I P SG V ++AAL R+
Sbjct: 517 AIDTDTGINSQIRYRXARDXINTFSIHPDSGIVSLIAALGRE 558
Score = 39.5 bits (88), Expect = 0.69
Identities = 43/144 (29%), Positives = 61/144 (42%), Gaps = 18/144 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ +GT II + A LD G N I Y S A + F I+ G
Sbjct: 606 IQESANVGTPIIXITATSLDIGXNADITY-------------SIAAGNEQGKFSIDPNKG 652
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK-TWYNFNV 1054
++V L E E+ + + A D G L D V + + DVND+ P F + +V
Sbjct: 653 VLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHV 712
Query: 1055 EEAQYTRRVLGKVDATDADFGQNA 1078
+ + + KV ATD D NA
Sbjct: 713 KXNVHEGTXIFKVMATDXDSLANA 736
Score = 39.1 bits (87), Expect = 0.92
Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 10/156 (6%)
Query: 1233 SSTAILMVTVADVPDEV-EMSDKPVFISRY-YELEIEENVNAPVELVSLNLTEHYENFKM 1290
S T+ +V ++ EV +++D P F + Y+ + E+ + +++ L ++
Sbjct: 144 SRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNP 203
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
+ L + F ID ++G + L+ DRE + Y + V S YP
Sbjct: 204 LKFTLGPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYP 263
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRP 1386
+T V++ + D NDN P F N P
Sbjct: 264 -------SLTT-TTSVLITVTDCNDNPPAFEKQNYP 291
Score = 37.1 bits (82), Expect = 3.7
Identities = 16/51 (31%), Positives = 36/51 (70%), Gaps = 2/51 (3%)
Query: 156 NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGK 206
N+D+ YSI +GN+ G F+++ +K VL++ + LD++ +E+ + ++A+ +
Sbjct: 629 NADITYSIAAGNEQGKFSID-PNKGVLVVTEPLDHELA-REYFITVLATDR 677
Score = 36.7 bits (81), Expect = 4.9
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 1441 ATDSDIGINADIRYQIL--NEQAPRFAIDPVSGTVRVVAALARDAGRVF 1487
AT DIG NADI Y I NEQ +F+IDP G + V L + R +
Sbjct: 621 ATSLDIGXNADITYSIAAGNEQG-KFSIDPNKGVLVVTEPLDHELAREY 668
>UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabditis
elegans|Rep: Cadherin-4 precursor - Caenorhabditis
elegans
Length = 4307
Score = 114 bits (275), Expect = 2e-23
Identities = 99/338 (29%), Positives = 154/338 (45%), Gaps = 25/338 (7%)
Query: 569 DIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
D P F P Y + + G +V + D E + + Y LL G E F+V R G
Sbjct: 2479 DKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLDGSESQF-FSVHPRQG 2537
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
ITV L + ++AN TV V ++ E + + ++S +F
Sbjct: 2538 TITVAKKLEHKAGVTLSL-TIKATDSANPPHHATTTVEV-NIASESVKVPRFSNSHYLFS 2595
Query: 688 VKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI----AIAEDGTIFTQK 742
V E++ G IG++ +RF I + +D G I +
Sbjct: 2596 VMEDADVGNVIGRVQQMETE------IDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKS 2649
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF-IMENSK 801
LDRE+++ ++MT+ A+ GV + I VT+ I D NDN P F H YE F I E++
Sbjct: 2650 SLDRERKNQWKMTIRADAAGGVHA---ITTVTVDIGDVNDNAPAF-HGDYERFTISEDAA 2705
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
+GT + I A D D+ + ++L E FD++EN+G + + LDREK Y
Sbjct: 2706 VGTSV---TIFSAMDRDDSPSGRIRFSLVEENP-YFDLNENSGWLT-VASQLDREKIDHY 2760
Query: 862 KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
KL A D GG +++ I++ D ND+ P+F + E N
Sbjct: 2761 KLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFN 2798
Score = 107 bits (258), Expect = 2e-21
Identities = 157/659 (23%), Positives = 277/659 (42%), Gaps = 78/659 (11%)
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-----QGENGEF 341
+++A + + D+ND +PEF + I ++ G + + ATD D E+ +
Sbjct: 2281 SSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKL 2340
Query: 342 TYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRI 400
Y++ D + F+I P +G L++ D + + + T+ +V A
Sbjct: 2341 LYKIVDGDETLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGIIVNKSALLTVA 2400
Query: 401 AKWRRQPLE------TNAPLEKTTYVFPDKVGTKTENIEY-----------YDEQLM--- 440
K PL+ T++ + +P + KT I Y L+
Sbjct: 2401 VKGGVPPLQFSLAPTTSSNSSTSKEAWPVAIDRKTGRIHVSRVLNYHRDKRYQIPLVVED 2460
Query: 441 -----SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+F + ++++D ND P FV Y S+ +AK G + V A D D +N +
Sbjct: 2461 ATGRRAFSTLTLSVIDINDKPPFFVLP-FYSTSISESAKEGDTVMMVSATDDD--ENDTI 2517
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH----ALFVEASDQPANPSERRYS 551
Y L S + F ++P GT++VA+ LE + +L ++A+D ANP
Sbjct: 2518 EYSLLDGSE---SQFFSVHPRQGTITVAKK--LEHKAGVTLSLTIKATDS-ANPPHH--- 2568
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
A T+EV ++ K +P F + Y F V + +G +G+++ + E +++ + ++
Sbjct: 2569 -ATTTVEVNIASESVK--VPRFSNSHYLFSVMEDADVGNVIGRVQQMET-EIDEIRFTIV 2624
Query: 612 HGYEEG---VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
G EE +PF+VE +G I V L R + + + + +T TV + D
Sbjct: 2625 PGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKM-TIRADAAGGVHAITTVTVDIGD 2683
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
VND G + F + E++A IF + + +G +RF + + D
Sbjct: 2684 VND-NAPAFHGDYER--FTISEDAAVGTSVTIF--SAMDRDDSPSGRIRFSLVEENPYFD 2738
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G + LDREK D Y++ A G + TI + D ND+PP FE
Sbjct: 2739 --LNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTD---LPFTIVVSDVNDSPPQFE 2793
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
E F ++ T + IK D + F + G + +F +D N ++
Sbjct: 2794 K---EEFNIDLHLPSTSPILHFSIKDDDLSPNNVSQF-FIPKGNEEGVFWIDSNNDLLLK 2849
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNK---PEFNQ---IEENSK 901
+ + E K+ Y+L + A D G + ++ I + D+ PE N+ + ENSK
Sbjct: 2850 RPEIV--ENKMQYQLKVTAFD-GVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSK 2905
Score = 107 bits (256), Expect = 3e-21
Identities = 145/538 (26%), Positives = 237/538 (44%), Gaps = 67/538 (12%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
L +A + ++ V+ KV I +E+L +V + +LD+ND+ PVF + +
Sbjct: 445 LRVSAKINRSERVYNFKVIASLHGI---NEKLAE-KDVSIEILDSNDHAPVFSAKWMRQT 500
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
+ K G V+ KV A D D G+NG ++Y TS L P +IN NTG +++ E P
Sbjct: 501 PIVIG-KPGDVLVKVDATDQDEGENGKIVYKF--TSEL----PLEINANTGEITLVEVPK 553
Query: 528 LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK---GNKPDI---------PDFMG 575
V A D P R +L ++ + GTK KP I P F
Sbjct: 554 KGNSWPATVWAIDL-GLPLSRMSALNLMFYK--NGTKIPAKPKPIIIQESENKHSPVFSS 610
Query: 576 APYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLH---GYEEGVPFAVEERSGVITV 631
P V + IGT V +++ ND N ++H G V V+E+SG ITV
Sbjct: 611 FPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEV-LTVDEQSGEITV 669
Query: 632 VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND-ERGVLLKGA---------- 680
DLS+ + E + +Q + + +N + + V+ + G +K +
Sbjct: 670 ASDLSKLMKE--KLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVKTMKLRIKD 727
Query: 681 ---HSP----IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI- 732
HSP + ++++ + IF + G G ++F + N Q+ + I+I
Sbjct: 728 VNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISID 787
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP--VFEHA 790
A+ G + K LDRE +DV+ +IA ++G + +TI +ED NDNPP V +H+
Sbjct: 788 AKTGIVKLLKSLDREDQDVHTFAIIAS-DEGFPMRVSVTNLTISVEDVNDNPPKCVVQHS 846
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
I E+ G + + + A D D G N+ + L E K F +D ++G +
Sbjct: 847 --RARIPEDLPHGAFV---SCMAAFDEDIGQNSKLKFLLNSE-KVPFRIDHHSGCIFIHA 900
Query: 851 DS--LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGD--ENDNKPEFNQIEENSKV 902
LD K + LS+ D G LS+ L + + D N EF+ + + + V
Sbjct: 901 PEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASV 958
Score = 95.1 bits (226), Expect = 1e-17
Identities = 115/440 (26%), Positives = 187/440 (42%), Gaps = 61/440 (13%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+++G + ++R +R VY VIA + G+ V+I I D ND+ PVF
Sbjct: 440 SKNGILRVSAKINRSER-VYNFKVIASLH-GINEKLAEKDVSIEILDSNDHAPVFSAKWM 497
Query: 793 EGFIMENSKIGTE-IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ K G +K+D ATD DEG N +Y E +++ NTG + +
Sbjct: 498 RQTPIVIGKPGDVLVKVD----ATDQDEGENGKIVYKFTSELP--LEINANTGEITLVEV 551
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
+K + ++ A D G S + ++ +N K I K I +E++
Sbjct: 552 P---KKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTK-----IPAKPKPIIIQESE-- 601
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY--- 968
NK + + + E+ PIGT + KL A D D+G NG IRY
Sbjct: 602 -------------NKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIH 648
Query: 969 -------------EFNSEVYIPP--SKLSADALEVKRYFVINERHGHVIVARSLPPESEF 1013
E + E+ + SKL + LEV V +H V ++ S F
Sbjct: 649 DIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKH----VTSNI---SNF 701
Query: 1014 RLNISALDGGN-LNDNI-SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+L +SA+D G + ++ ++++ +KDVN+H P F + Y + E + + + KV A D
Sbjct: 702 QLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTAND 761
Query: 1072 ADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D G N + + + + I TG++ + LDRE +D + ++A D G
Sbjct: 762 FDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEG-FPM 820
Query: 1131 XXXXXXXXXXXXDVNDNSPK 1150
DVNDN PK
Sbjct: 821 RVSVTNLTISVEDVNDNPPK 840
Score = 90.2 bits (214), Expect = 4e-16
Identities = 85/292 (29%), Positives = 129/292 (44%), Gaps = 22/292 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F +++ +GV+TVV L ++ VA + V V+D ND K
Sbjct: 3038 FQIDDINGVVTVVKPLDSEILGFFNLTVVA--SDGEFEDKATILVTVIDQNDNAPTFEKS 3095
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTI 738
+S + ++ S G ++ H S G+ + + + DVT + + A+ G +
Sbjct: 3096 TYSMKV--MESESIGY---ELAHFRASG--GDQNETIEYYL-KPSDVTSFVNLNAQTGIL 3147
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
KPLD E ++TV+A+ + GV QV I + DENDN P FE Y G + E
Sbjct: 3148 TLAKPLDFETLSALKLTVVAK-DSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKE 3206
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE-----NTGVVKFIGDSL 853
NSK G ++ +KA D D Y L + D N+ I S+
Sbjct: 3207 NSKSGEKVL---TVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSI 3263
Query: 854 DREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
D EK Y L ++A+D G L SEA L I + DEND+ P F+ + V+
Sbjct: 3264 DYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQ 3315
Score = 89.8 bits (213), Expect = 5e-16
Identities = 111/462 (24%), Positives = 206/462 (44%), Gaps = 37/462 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL S V V V +LD NDN+P F + ++ +S++S K + ++ AVD D G+N +
Sbjct: 1148 EPQLCSNVIVIVNVLDENDNSPTFTQA-IHHYSVRS--KFAGKLCRIFAVDADEGENARL 1204
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y++ + F I+ N G + +E+ + +AL V+A+D P ++ + VV
Sbjct: 1205 TYNITEGD-----ARFSID-NNGNIIASEAIHGDESYALTVQATDH-GTPGQQFAATRVV 1257
Query: 556 TIEVTRGTK--GNKPDIPDFMG--APYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
+ G K +K P+ G + Y + +G +VG++ +DA + +++ + +
Sbjct: 1258 LTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDA-DGDELWWSIS 1316
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G + V F V + +G + + + R A ++TV ++ V+
Sbjct: 1317 SGDPDSV-FDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQA----WDHSTV-IIQVSR 1370
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT--DD 729
+ K + S V E A+G +T +S GT + F + + DV D
Sbjct: 1371 QISQRPKFSASHYQTDVSER---VAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDK 1427
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I + G + +PLD E R+ + + + + + V I DENDN P F
Sbjct: 1428 IRVEPSSGNVIVMEPLDYEA--ARRIRAVVQVQQANMKSFATFSVN--INDENDNSPYFV 1483
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
T F+ E+ + + + A D D G N + Y++ G + +F +D +G V+
Sbjct: 1484 GHTAFAFVDESDTVDDVLA---TVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVR 1540
Query: 848 FIGDSLDRE-KKIMYKLSLVARDTGGLSSEAELIIMIGDEND 888
+ LD E + + L + A D+ S + E+ + I + N+
Sbjct: 1541 -LAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIRNSNE 1581
Score = 89.4 bits (212), Expect = 7e-16
Identities = 123/488 (25%), Positives = 204/488 (41%), Gaps = 48/488 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S +++ + D N+++P F + Y + N K G I KV A D D G NG + + L
Sbjct: 717 SVKTMKLRIKDVNNHSPQFDEVSYY-LRISENEKPGKDIFKVTANDFDGGNNGKIKFSLG 775
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQ--PANPSERRYSLAVVT 556
+N +S I+ TG V + +S E + H + ASD+ P S +++V
Sbjct: 776 --NNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVED 833
Query: 557 IEVTRG---TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+ + ++ IP+ + P+ +V +GQ N LL+
Sbjct: 834 VNDNPPKCVVQHSRARIPEDL--PHGAFVSCMAAFDEDIGQ---------NSKLKFLLNS 882
Query: 614 YEEGVPFAVEERSGVITVVDD---LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
E VPF ++ SG I + L + P ++ ++ + ++ + + T+ +HV V+
Sbjct: 883 --EKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNL-SIEVADHGDPILSTSCHLHVELVD 939
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD---VT 727
+ H I F A T + I TG+ + + A + +
Sbjct: 940 ------IAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIG 993
Query: 728 DD----IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI----SGAGIYQVTIYIED 779
D +I + GT+ T LDRE + Y +TV A +K + + V I I D
Sbjct: 994 GDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILD 1053
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFD 838
ND+ PV + Y + ENS I A D D A M+ + G+ + F
Sbjct: 1054 RNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFR 1113
Query: 839 VDENTGVVKFIG-DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+D +G + G LDREK+ ++L + D G L S +I+ + DENDN P F Q
Sbjct: 1114 IDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQ 1173
Query: 896 IEENSKVR 903
+ VR
Sbjct: 1174 AIHHYSVR 1181
Score = 81.8 bits (193), Expect = 1e-13
Identities = 121/519 (23%), Positives = 219/519 (42%), Gaps = 55/519 (10%)
Query: 453 NDNNPVFVPSNLYEF-SMKSNAKVGTVIGKVKAVDPDLGQNGMVLY---DLQRTSNLTIT 508
N ++PVF S+ E + +A +GTV+ K++A D D G NG + Y D+ +S+ +T
Sbjct: 602 NKHSPVF--SSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLT 659
Query: 509 SPFKINPNTGTVSVAE--SPILEGR-HALFVEASD-QPANPSERRYSLAVVTIEVTRGTK 564
++ +G ++VA S +++ + L V+ + + + L V I+ K
Sbjct: 660 ----VDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVK 715
Query: 565 GNKPDI-----------PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
+ + P F Y + N G + ++ ND N+ + + L
Sbjct: 716 SSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLG 775
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVN 670
+ E+ +++ ++G++ ++ L R ++ ++ F +A E + + VTN T+ V DVN
Sbjct: 776 NNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVN 835
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + HS + E+ A I N ++FL+ N + V I
Sbjct: 836 DNPPKCVV-QHSRA--RIPEDLPHGAFVSCMAAFDEDIGQNS--KLKFLL-NSEKVPFRI 889
Query: 731 AIAEDGTIFT---QKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
G IF + PLD K + +++ +A+ ++S + V + N
Sbjct: 890 D-HHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIE 948
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
F+ E + ENS+IGTE+ M + D + Y + G+G F +D+ G
Sbjct: 949 FDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQK-GT 1007
Query: 846 VKFIGDSLDREKKIMYKLSLVARDT-GGLSSE------AELIIMIGDENDNKPEFNQIEE 898
V+ LDRE K Y +++ ARD+ L + + I I D ND++P
Sbjct: 1008 VR-TTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRP------V 1060
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPL 937
K N A I++V+ + +D D PL
Sbjct: 1061 AKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPL 1099
Score = 80.6 bits (190), Expect = 3e-13
Identities = 109/405 (26%), Positives = 179/405 (44%), Gaps = 49/405 (12%)
Query: 511 FKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F I+P TG +S + + + A L V+A NP R +L VV IE
Sbjct: 1941 FFIHPGTGVISSSGIALDREKSAIIRLVVQAKSHEKNPVMAR-ALVVVGIE------NIN 1993
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
+ P FMG PY+ +G + IGT V + +V D ND D++ E +P + G
Sbjct: 1994 DETPIFMGTPYDITIGHS-DIGTVVLEPKVID----NDEG-DVVTISSENMPEYFKIVGG 2047
Query: 628 VITVVDDLSRYNRP--MYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
+ + L ++F+ +A + + + VVD R V + ++ +I
Sbjct: 2048 KVVLGKKLPSIEEEDLEFNFKLIAKDNGSVHRVEEPVKIRVVD--KARPVFSQNVYTAVI 2105
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD------VTDDIAIAEDGTIF 739
KE++ + + + SS+ G + + I +++ +T ++ + +
Sbjct: 2106 S--KESTKKSTV-LVKVMAKSSLQSKSKGLIGYRILDKKSPFSVDFLTGEVRLNNLKMLA 2162
Query: 740 -TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T + E R+V R +IA+ +I +GI + PVFE Y E
Sbjct: 2163 ETNYTFEVEAREVTRPKMIAKAQVEIIVKSGI----------TTHAPVFEKLKYTASTPE 2212
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
++ IG + IKAT +DE N Y+L G + ++ TG V G LD EK
Sbjct: 2213 STSIGQRLLT---IKATTSDE--NDTIEYSL--SGSKDIEIHPETGDVTITGQ-LDYEKT 2264
Query: 859 IMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
Y L LVA +G +SSEAE I++I D ND PEF + + ++K+
Sbjct: 2265 QKYDLKLVATSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDVSAKI 2309
Score = 78.6 bits (185), Expect = 1e-12
Identities = 81/279 (29%), Positives = 121/279 (43%), Gaps = 27/279 (9%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I++ +G V V + L E F L + A DG D ++ V V D ND+ P F+K+
Sbjct: 3038 FQIDDINGVVTVVKPLDSEILGFFNLTVVASDG-EFEDKATILVTVIDQNDNAPTFEKST 3096
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y+ V E++ L A+ D QN + Y+++PSD ++ TG+L++ LD
Sbjct: 3097 YSMKVMESESIGYELAHFRASGGD--QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLD 3154
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
ET LTVVA+D+G D NDN+PKF + K+ + +
Sbjct: 3155 FETLSALKLTVVAKDSG-VPPLETEAQVEISVMDENDNAPKFE------KEKYVGKVKEN 3207
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD-----FIGNGNG--LILYSLPQRK 1222
+ + E V+ + E + + V TD F N NG LI S+ K
Sbjct: 3208 SKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEK 3267
Query: 1223 -NQQNL-------GLPSLSSTAILMVTVADVPDEVEMSD 1253
+ NL G P L S A+L + V D D D
Sbjct: 3268 IKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFD 3306
Score = 70.1 bits (164), Expect = 4e-10
Identities = 110/470 (23%), Positives = 188/470 (40%), Gaps = 42/470 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+S N+ +++ D NDN P V + + + G + + A D D+GQN + + L
Sbjct: 822 VSVTNLTISVEDVNDNPPKCVVQH-SRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLL 880
Query: 500 QRTSNLTITSPFKINPNTGTVSV-AESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
PF+I+ ++G + + A L+ F S + A+ + S + +
Sbjct: 881 NSEK-----VPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTS-CHLH 934
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV-----SYDLLHG 613
V + +F E V N IGT V I + ++ V Y ++ G
Sbjct: 935 VELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGG 994
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL------SIVTNATVHVV 667
+G P ++ G + L R + Y A +L V + + ++
Sbjct: 995 --DGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRIL 1052
Query: 668 DVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
D ND R V K + I V ENS A I ++ T+ + + + F I
Sbjct: 1053 DRNDHRPVAKKPMY---IASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQ 1109
Query: 727 TDDIAIAEDGTIFTQ--KPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDN 783
+ G I T + LDREK+ + + V I + + + I V + + DENDN
Sbjct: 1110 SFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVI--VIVNVLDENDN 1167
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F A + + SK ++ I A DADEG NA Y + EG F +D N
Sbjct: 1168 SPTFTQAIHHYSV--RSKFAGKLCR---IFAVDADEGENARLTYNI-TEGDARFSIDNNG 1221
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
++ +++ ++ Y L++ A D G G A +++ + KP
Sbjct: 1222 NII--ASEAIHGDES--YALTVQATDHGTPGQQFAATRVVLTANSAGQKP 1267
Score = 69.7 bits (163), Expect = 6e-10
Identities = 103/460 (22%), Positives = 183/460 (39%), Gaps = 43/460 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNL---YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ V + + NDN P + L + ++ ++ I ++ A D D + + D
Sbjct: 2976 ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVD--- 3032
Query: 502 TSNLTITSPFKINPNTGTVSVA---ESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
F+I+ G V+V +S IL G L V ASD E + ++ V I+
Sbjct: 3033 ----DFGGLFQIDDINGVVTVVKPLDSEIL-GFFNLTVVASD---GEFEDKATILVTVID 3084
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ P F + Y V + IG + R + + + Y L +
Sbjct: 3085 -------QNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPS--DVT 3135
Query: 619 PFA-VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F + ++G++T+ L VA +++ + T A V + V DE
Sbjct: 3136 SFVNLNAQTGILTLAKPLDFETLSALKLTVVA-KDSGVPPLETEAQVEI-SVMDENDNAP 3193
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD-----IAI 732
K + VKENS ++ + G V + + + T D AI
Sbjct: 3194 KFEKEKYVGKVKENSKSGE--KVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAI 3251
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+G + + +D EK Y + VIA+ + G + I++EDEND+ P F+
Sbjct: 3252 NSNGDVLISQSIDYEKIKKYNLKVIAK-DGGRPPLRSEALLEIHVEDENDHAPTFDDCNM 3310
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ E IG + ++ +D D N A F + G+G + F V+E ++
Sbjct: 3311 TALVQEGEAIGHRLLKFSV---SDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELL--TAK 3365
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
L+ KK Y L+++A+D G +++ L I I + + P
Sbjct: 3366 KLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAP 3405
Score = 67.3 bits (157), Expect = 3e-09
Identities = 73/271 (26%), Positives = 113/271 (41%), Gaps = 18/271 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR------ 136
+TV IE++NDN P ++ V++DE PT E A ++ + R
Sbjct: 2976 ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVDDFG 3035
Query: 137 GLTIFKDIRAFDRD-KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
GL DI KP +++ DG F +++ +L V+D +
Sbjct: 3036 GLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEFEDKAT-----ILVTVIDQNDNAP 3090
Query: 196 EFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL 255
F+ S K + E + E H T+ Y L + +L++ G L L
Sbjct: 3091 TFEKSTY-SMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTL 3149
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
K LD + L+ L V A P +A+VEI ++D NDN P+FE + Y +
Sbjct: 3150 AKPLDFETLSALK-----LTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKV 3204
Query: 316 VENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
EN +G VL V A D D G +Y+L+
Sbjct: 3205 KENSKSGEKVLTVKALDVDSEHFGAVSYELE 3235
Score = 66.9 bits (156), Expect = 4e-09
Identities = 43/166 (25%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Query: 202 MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDL 261
M +G + + L P + AID+D G + Y ++S D ++FS+D +G++ + D
Sbjct: 1698 MPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGAIRTQMSFDF 1757
Query: 262 DAEHNLQANTFVLQVQASQLNNPLKTA--QARVEIELLDLNDNLPEFEVDFYNISIVENL 319
+ + + VQA + P + + + + + ++D ND P F + +IS++
Sbjct: 1758 E-----KMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPT 1812
Query: 320 PNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRN 365
NG SV A D D G Y + D FS+D ++G + V++
Sbjct: 1813 ANGVSVGGQTAQDMD--SVGSLRYFIKDQSVPFSVDSKTGDVLVKD 1856
Score = 66.1 bits (154), Expect = 7e-09
Identities = 86/366 (23%), Positives = 139/366 (37%), Gaps = 36/366 (9%)
Query: 38 QSIDSLVDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDN 93
Q S++ D+ +VK D ++ D ++ G + ++T+ +EDVNDN
Sbjct: 778 QEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDN 837
Query: 94 VPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGP---------SLTIPLTVPRGL-T 139
P + + E P G AF+ +A IG S +P +
Sbjct: 838 PPKCVVQHSRARIPEDLPHG--AFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGC 895
Query: 140 IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL-----RKVLDYDAGD 194
IF + D TP ++ + D S H V L+ +++D
Sbjct: 896 IFIHAPEYPLDYHKTPFFNLSIEVADHGDP--ILSTSCHLHVELVDIAHNHLAIEFDDVA 953
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
KE + I E++ E D+ L Y +I G+ FS+D G++
Sbjct: 954 KEASVY---ENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQ-KGTVR 1009
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
LD + + + +P + V I +LD ND+ P + Y S
Sbjct: 1010 TTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIAS 1069
Query: 315 IVENLPNGFSVLQVMATDKDQGENGE-----FTYQLDDPKGAFSIDPRSGWLTVRNQTVL 369
+ EN P +++V ATD D +N F + DP+ F ID SG++T L
Sbjct: 1070 VAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRL 1129
Query: 370 DREAHS 375
DRE S
Sbjct: 1130 DREKQS 1135
Score = 65.7 bits (153), Expect = 9e-09
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 15/190 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G ++ + ALD+DS G + YE E+ S+ + D + F IN +G
Sbjct: 3204 VKENSKSGEKVLTVKALDVDSEHFGAVSYEL--EIV---SETTTDTPVLP--FAINS-NG 3255
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V++++S+ E ++ L + A DGG L + + V+D NDH P F V+
Sbjct: 3256 DVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQ 3315
Query: 1056 EAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + L K +D D +N A T IQ D F+++ +L+ +L+ +D
Sbjct: 3316 EGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQ-GDGAKSFKVNEKLELLTAK-KLEYRKKD 3373
Query: 1115 KYILTVVARD 1124
KY+LTV+A+D
Sbjct: 3374 KYLLTVIAKD 3383
Score = 60.9 bits (141), Expect = 3e-07
Identities = 118/544 (21%), Positives = 204/544 (37%), Gaps = 40/544 (7%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ + SF V + D NDN+P FV + F +S+ V V+ V A D D G+
Sbjct: 1455 VQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDT-VDDVLATVTAFDKDRGE 1513
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSER 548
NG+V Y + + S FKI+ +G V +A+ E +H L + A D AN +
Sbjct: 1514 NGIVTYSIVSGNE---ESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKD 1570
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
SL + P+ F Y+ + + GT V V +A VSY
Sbjct: 1571 EMSLHI-------RNSNEAPETAKFDRKVYQTTLYDSTRPGTPV---LVLNALHHGTVSY 1620
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRY-NRPMYDFEAVALQENANLSIVTNATVHVV 667
L F V SG + + L++ +R + A+ ++ + ++
Sbjct: 1621 KL---EPNCTFFEVHTLSGAVHLATWLTKLKHRKSVECTAI-VESTEGQQDIAKVIAKII 1676
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN--GTGNVRFLIANQQD 725
N + + + I + + +S+I + G V + + + +D
Sbjct: 1677 RTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKD 1736
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ--VTIYIEDENDN 783
G I TQ D EK Y V A F+ G + + + + DEND
Sbjct: 1737 EQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQA-FDMGQPPRRSLMPSLIVVTVIDENDE 1795
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
PP F + + ++ + G + A D D + + + F VD T
Sbjct: 1796 PPRFPSNSLDISMILPTANGVSVGGQT---AQDMDSVGSLRY---FIKDQSVPFSVDSKT 1849
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
G V + + ++ L + D +S I I EN +K +F + E ++ +
Sbjct: 1850 GDVLVKDSNGISDMTKLFDLEVFVTDGKQSASYVMKISTISTEN-SKFKFTRNEYHTSL- 1907
Query: 904 IHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
I T G+ ++ + K V+ F+ P GT +I + + LD +
Sbjct: 1908 IENTTLPPGSIILSVATIGDKLDHFSIVNPHEAFFIHP-----GTGVISSSGIALDREKS 1962
Query: 964 GQIR 967
IR
Sbjct: 1963 AIIR 1966
Score = 60.5 bits (140), Expect = 3e-07
Identities = 47/175 (26%), Positives = 86/175 (49%), Gaps = 22/175 (12%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELD---------LDAE-H 265
+ A D+D G +RY + I+G+ ++ ++D +G + + +L LD + H
Sbjct: 630 LQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQVH 689
Query: 266 NLQANT-----FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
++ T F L+V A P+K++ +++ + D+N++ P+F+ Y + I EN
Sbjct: 690 YIKHVTSNISNFQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEK 749
Query: 321 NGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
G + +V A D D G NG+ + L + SID ++G V+ LDRE
Sbjct: 750 PGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTG--IVKLLKSLDRE 802
Score = 60.5 bits (140), Expect = 3e-07
Identities = 42/147 (28%), Positives = 74/147 (50%), Gaps = 6/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G +++ L + ++ + S+D+ G + L K LD + + +TF +
Sbjct: 757 VTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQ---DVHTFA--I 811
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS P++ + + I + D+NDN P+ V I E+LP+G V + A D+D G
Sbjct: 812 IASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIG 871
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTV 363
+N + + L+ K F ID SG + +
Sbjct: 872 QNSKLKFLLNSEKVPFRIDHHSGCIFI 898
Score = 60.5 bits (140), Expect = 3e-07
Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 13/146 (8%)
Query: 231 LRYELISGNDRK----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
+R+ ++ G++ FS++ G + ++ LD + + N + + ++A
Sbjct: 2619 IRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERK-----NQWKMTIRADAAGGV-- 2671
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
A V +++ D+NDN P F D+ +I E+ G SV A D+D +G + L
Sbjct: 2672 HAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLV 2731
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ F ++ SGWLTV +Q LDRE
Sbjct: 2732 EENPYFDLNENSGWLTVASQ--LDRE 2755
Score = 60.1 bits (139), Expect = 5e-07
Identities = 83/342 (24%), Positives = 152/342 (44%), Gaps = 43/342 (12%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-------- 121
I AG S+ ++ + I+DVN++ P F + Y++ + E G+ F
Sbjct: 708 IDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNN 767
Query: 122 APIGPSL------TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALE 175
I SL + +++ I K +++ DR+ + DVH + +D+G F +
Sbjct: 768 GKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDRE-----DQDVHTFAIIASDEG-FPMR 821
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI---LFPEPIHAIDQDLGVGATLR 232
S + + + D D + V+ S RI +++ F + A D+D+G + L+
Sbjct: 822 VSVTNLTISVE----DVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLK 877
Query: 233 YELISGNDRKLFSLDSVNGSLFLEK-ELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
+ L S ++ F +D +G +F+ E LD + F L ++ + +P+ +
Sbjct: 878 FLLNS--EKVPFRIDHHSGCIFIHAPEYPLDYH---KTPFFNLSIEVADHGDPILSTSCH 932
Query: 292 VEIELLDLNDNLPEFEVDFY--NISIVENLPNGFSVLQVMATD-----KDQGENGEFTYQ 344
+ +EL+D+ N E D S+ EN G V+ + A + K + EN E+
Sbjct: 933 LHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRII 992
Query: 345 LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
D FSID + TVR +LDRE S+ + V A+++
Sbjct: 993 GGDGWPHFSIDQKG---TVRTTHLLDRETKSAYWITVEARDS 1031
Score = 59.7 bits (138), Expect = 6e-07
Identities = 59/236 (25%), Positives = 101/236 (42%), Gaps = 30/236 (12%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+D++ P F++P E+ G T++ ++A D D N I Y
Sbjct: 2475 IDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDE--NDTIEYSL----------- 2521
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVN 1039
D E ++F ++ R G + VA+ L ++ L I A D N + + V V +
Sbjct: 2522 -LDGSE-SQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIAS 2579
Query: 1040 DHF--PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEIS 1096
+ P F + Y F+V E V+G+V + + + + + SD+ LPF +
Sbjct: 2580 ESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVE 2639
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
TG + V LDRE ++++ +T+ A G DVNDN+P F+
Sbjct: 2640 RSTGKIIVKSSLDRERKNQWKMTIRADAAG---GVHAITTVTVDIGDVNDNAPAFH 2692
Score = 58.0 bits (134), Expect = 2e-06
Identities = 134/623 (21%), Positives = 232/623 (37%), Gaps = 68/623 (10%)
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGK 834
E EN + PVF + E++ IGT + ++A D D G N Y + G
Sbjct: 599 ESENKHSPVFSSFPEIVEVTEDAPIGTVVAK---LQANDEDTGYNGFIRYVIHDIAGSSH 655
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
E+ VDE +G + D K+M K L D + I N F
Sbjct: 656 EVLTVDEQSGEITVASDL----SKLM-KEKLEVLDVQ--------VHYIKHVTSNISNF- 701
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
Q++ ++ I T + + + +K N + D++ I EN G I K+
Sbjct: 702 QLKVSA---IDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVT 758
Query: 955 ALDLDSGLNGQIRYEF-NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEF 1013
A D D G NG+I++ N++ + A VK ++ V + + F
Sbjct: 759 ANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGF 818
Query: 1014 RLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
+ +S ++ + V+DVND+ P + E + + A D D
Sbjct: 819 PMRVSV---------TNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDED 869
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG---ELDRETEDKYILTVVARDNGXXXX 1130
GQN+ L + + + +PF I +G + ++ LD + L++ D+G
Sbjct: 870 IGQNSKLKFLL--NSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHG-DPI 926
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
D+ N FD++ + EA N + +++ K T +E
Sbjct: 927 LSTSCHLHVELVDIAHNHLAI-EFDDVAK----EASVYENSEIGTEVIMIEAKETGDEQ- 980
Query: 1191 PIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV 1249
KV A + ++ I G+G +S+ Q+ + L + + +TV +
Sbjct: 981 -------KVKAENLEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKT 1033
Query: 1250 EMSDKP--VFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILN---------EN 1298
++ P + + ++ N + PV + + EN I+ +N
Sbjct: 1034 DLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDN 1093
Query: 1299 DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEG 1358
D F I+ R R T I R +R+K S H ++ D E
Sbjct: 1094 DAAAPLMFKIE-RGDPQSFFRIDLTSGYITTSGIRRLDREKQSE---HELWVSICDGGEP 1149
Query: 1359 MTKYDVKVVVRIKDVNDNSPKFT 1381
+V V+V + D NDNSP FT
Sbjct: 1150 QLCSNVIVIVNVLDENDNSPTFT 1172
Score = 57.2 bits (132), Expect = 3e-06
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 15/188 (7%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LF +D +NG + + K LD + F L V AS K A + + ++D NDN
Sbjct: 3037 LFQIDDINGVVTVVKPLDSEI-----LGFFNLTVVASDGEFEDK---ATILVTVIDQNDN 3088
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
P FE Y++ ++E+ G+ + A+ DQ E E+ + D +++ ++G LT
Sbjct: 3089 APTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILT 3148
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTTYVF 421
+ LD E S+L++ V AK++ + T A + NAP EK YV
Sbjct: 3149 LAKP--LDFETLSALKLTVVAKDSGVPPLETEAQVEISV----MDENDNAPKFEKEKYVG 3202
Query: 422 PDKVGTKT 429
K +K+
Sbjct: 3203 KVKENSKS 3210
Score = 57.2 bits (132), Expect = 3e-06
Identities = 98/407 (24%), Positives = 163/407 (40%), Gaps = 41/407 (10%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + + VT++D NDN P F S Y + + +G + +A D QN +
Sbjct: 3069 DGEFEDKATILVTVIDQNDNAPTFEKST-YSMKVMESESIGYELAHFRASGGD--QNETI 3125
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
Y L+ + +TS +N TG +++A+ E A L V A D P E A
Sbjct: 3126 EYYLKPSD---VTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETE---A 3179
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLL 611
V I V + P F Y V N G V ++ D ++ VSY+L
Sbjct: 3180 QVEISV----MDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELE 3235
Query: 612 HGYEEG-----VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TV 664
E +PFA+ +G + + + Y+ + +A ++ + + A +
Sbjct: 3236 IVSETTTDTPVLPFAINS-NGDVLISQSIDYEKIKKYNLKVIA-KDGGRPPLRSEALLEI 3293
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQ 723
HV D ND + ++ G AIG ++ ++S + G G F + Q
Sbjct: 3294 HVEDENDHAPTFDDCNMTALV------QEGEAIGHRLLKFSVSDLDGPKNG-APFTVEIQ 3346
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D + E + T K L+ K+D Y +TVIA+ KG + +TI+I + +
Sbjct: 3347 GDGAKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDC---PLTIFIRQTSRH 3403
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTL 829
P + + ++N I +KA+D D E N L + L
Sbjct: 3404 APTMKPMKIQINTLQNELPEGII---GRLKASDEDEEDQNGLLRFGL 3447
Score = 56.8 bits (131), Expect = 4e-06
Identities = 57/199 (28%), Positives = 94/199 (47%), Gaps = 25/199 (12%)
Query: 936 PLFL--IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
P+++ + EN P I+K+ A D D N P + + + +F
Sbjct: 1064 PMYIASVAENSPANVVIVKVEATDADDVDNDAAA----------PLMFKIERGDPQSFFR 1113
Query: 994 INERHGHVIVA--RSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
I+ G++ + R L E SE L +S DGG L N+ V V V D ND+ P F +
Sbjct: 1114 IDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQ 1173
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
++++V +++ + L ++ A DAD G+NA LTY I ++ D F I +++
Sbjct: 1174 AIHHYSVR-SKFAGK-LCRIFAVDADEGENARLTYNI--TEGDARFSIDNNGNIIASEA- 1228
Query: 1108 LDRETEDKYILTVVARDNG 1126
++ Y LTV A D+G
Sbjct: 1229 --IHGDESYALTVQATDHG 1245
Score = 56.8 bits (131), Expect = 4e-06
Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A + + + ++D+ND P F + FY+ SI E+ G +V+ V ATD D+ + E++
Sbjct: 2464 RRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLD 2523
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NP 388
FS+ PR G +TV + L+ +A +L + + A ++ NP
Sbjct: 2524 GSESQFFSVHPRQGTITVAKK--LEHKAGVTLSLTIKATDSANP 2565
Score = 55.6 bits (128), Expect = 1e-05
Identities = 80/324 (24%), Positives = 135/324 (41%), Gaps = 28/324 (8%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTV---DELTPTGEKAFIFLIAPIGPSLTIP 131
N + A V V IE++ND PIF+ TPY +T+ D T E I G +TI
Sbjct: 1977 NPVMARALVVVGIENINDETPIFMGTPYDITIGHSDIGTVVLEPKVI--DNDEGDVVTIS 2034
Query: 132 L-TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLD 189
+P I + P+ D+ ++ + D+G ++ +PV + +V+D
Sbjct: 2035 SENMPEYFKIVGGKVVLGKKLPSIEEEDLEFNFKLIAKDNG--SVHRVEEPVKI--RVVD 2090
Query: 190 --YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLD 247
+ +++ +L + Q G + Y ++ + + FS+D
Sbjct: 2091 KARPVFSQNVYTAVISKESTKKSTVLVKVMAKSSLQSKSKG-LIGYRIL--DKKSPFSVD 2147
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD-LNDNLPEF 306
+ G + L L + AE N + +V+A ++ P A+A+VEI + + + P F
Sbjct: 2148 FLTGEVRL-NNLKMLAETN-----YTFEVEAREVTRPKMIAKAQVEIIVKSGITTHAPVF 2201
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQ 366
E Y S E+ G +L + AT D EN Y L K I P +G +T+ Q
Sbjct: 2202 EKLKYTASTPESTSIGQRLLTIKATTSD--ENDTIEYSLSGSKD-IEIHPETGDVTITGQ 2258
Query: 367 TVLDREAHSSLRMKVYAKETNPSV 390
LD E +K+ A + V
Sbjct: 2259 --LDYEKTQKYDLKLVATSSGKQV 2280
Score = 55.6 bits (128), Expect = 1e-05
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 19/217 (8%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
LF + E+ +G I ++ ++ + +IR+ +P S+ S L F +
Sbjct: 2593 LFSVMEDADVGNVIGRVQQMETEID---EIRFTI-----VPGSEESDSFLP----FSVER 2640
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G +IV SL E +++++ I A G ++ +V V + DVND+ P F + F +
Sbjct: 2641 STGKIIVKSSLDRERKNQWKMTIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTI 2700
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + A D D + + + + + + F+++ +G L+V +LDRE D
Sbjct: 2701 SEDAAVGTSVTIFSAMDRDDSPSGRIRFSL--VEENPYFDLNENSGWLTVASQLDREKID 2758
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y L A D G DVND+ P+F
Sbjct: 2759 HYKLIARATDEG---GFNTDLPFTIVVSDVNDSPPQF 2792
Score = 55.2 bits (127), Expect = 1e-05
Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 20/189 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F I E+ +GT++ +A+D D +G+IR+ +E YF +NE
Sbjct: 2698 FTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSL---------------VEENPYFDLNEN 2742
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G + VA L E ++L A D G N ++ + V DVND P F+K +N ++
Sbjct: 2743 SGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL- 2801
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
T +L D D N +FI + + F I +L E+ E + +
Sbjct: 2802 HLPSTSPIL-HFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNNDLLLKRPEI-VENKMQ 2859
Query: 1116 YILTVVARD 1124
Y L V A D
Sbjct: 2860 YQLKVTAFD 2868
Score = 54.0 bits (124), Expect = 3e-05
Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 5/161 (3%)
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
K + +A + I+ E A D D A L +++ G+ + F +D +G +
Sbjct: 1063 KPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYIT 1122
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
LD E + +V + P + V + +LD NDN P F ++ S
Sbjct: 1123 TSGIRRLDREKQSEHELWVSICDGGE---PQLCSNVIVIVNVLDENDNSPTFTQAIHHYS 1179
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
+ + ++ A D D+GEN TY + + FSID
Sbjct: 1180 VRSKFAG--KLCRIFAVDADEGENARLTYNITEGDARFSID 1218
Score = 53.6 bits (123), Expect = 4e-05
Identities = 100/427 (23%), Positives = 170/427 (39%), Gaps = 48/427 (11%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT- 139
L T+ + DVND+ P F +++ + + + F + P+ +P+G
Sbjct: 2776 LPFTIVVSDVNDSPPQFEKEEFNIDLHLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEE 2835
Query: 140 -IFKDIRAFDR--DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
+F D +P + + Y + DG F E+S K + L+ D D E
Sbjct: 2836 GVFWIDSNNDLLLKRPEIVENKMQYQLKVTAFDGVF--ETSTKVKINLKSSKDSDIRCPE 2893
Query: 197 F-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL 255
+ VI+A + +L + LG T + +S ND +F ++ NG + +
Sbjct: 2894 ANKTVILAENSKKGTVVLGESSL------LGPNVTFK---LSDNDGNVFVVNFRNGIVKV 2944
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
++ +D E N Q L +Q + + + + + + +LNDN P+ +SI
Sbjct: 2945 KESDQIDYEKNQQLEFHRLTIQDNS-----EVCKELITVVIENLNDNRPKIIEKLLKVSI 2999
Query: 316 VENLPNGFS----VLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDR 371
ENLP + +++A D D E +F +DD G F ID +G +TV LD
Sbjct: 3000 DENLPTSEDARQYITRIVAEDADFDEI-KFR-MVDDFGGLFQIDDINGVVTVVKP--LDS 3055
Query: 372 EAHSSLRMKVYAK----ETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTY-----VFP 422
E + V A E +++ T D A + + +E + F
Sbjct: 3056 EILGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFR 3115
Query: 423 DKVGTKTENIEYY--DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG 480
G + E IEYY + SFVN+ N + + +F S K+ TV+
Sbjct: 3116 ASGGDQNETIEYYLKPSDVTSFVNL-------NAQTGILTLAKPLDFETLSALKL-TVVA 3167
Query: 481 KVKAVDP 487
K V P
Sbjct: 3168 KDSGVPP 3174
Score = 52.8 bits (121), Expect = 7e-05
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
Query: 1031 VRVFVKD-VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
V + VK + H PVF+K Y + E+ + L + AT +D +N + Y + S
Sbjct: 2186 VEIIVKSGITTHAPVFEKLKYTASTPESTSIGQRLLTIKATTSD--ENDTIEYSLSGSKD 2243
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
EI P TG +++ G+LD E KY L +VA +G DVND P
Sbjct: 2244 ---IEIHPETGDVTITGQLDYEKTQKYDLKLVATSSG--KQVSSEAEFIVLIEDVNDEMP 2298
Query: 1150 KFYAFD 1155
+F D
Sbjct: 2299 EFIRSD 2304
Score = 52.4 bits (120), Expect = 9e-05
Identities = 63/223 (28%), Positives = 98/223 (43%), Gaps = 21/223 (9%)
Query: 992 FVINERHGHVIVARSLP-PESEFRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKK 1047
F I ++G + V+ + E + + A G +N+ ++ V + + D NDH PVF
Sbjct: 436 FAIGSKNGILRVSAKINRSERVYNFKVIASLHG-INEKLAEKDVSIEILDSNDHAPVFSA 494
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
W VL KVDATD D G+N + Y ++LP EI+ TG +++ E
Sbjct: 495 KWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVY---KFTSELPLEINANTGEITL-VE 550
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
+ ++ + + TV A D G N K A + + + E++
Sbjct: 551 VPKK-GNSWPATVWAIDLGLPLSRMSALNLMFY-----KNGTKIPAKPKPIIIQ--ESEN 602
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+ F S I + E+APIGT VAK+ AND D NG
Sbjct: 603 KHSPVFSSFPEI----VEVTEDAPIGTVVAKLQANDEDTGYNG 641
Score = 50.4 bits (115), Expect = 4e-04
Identities = 86/409 (21%), Positives = 159/409 (38%), Gaps = 37/409 (9%)
Query: 994 INERHGHVIVARSLPPESEFRLNISAL--DGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
I+ + G + V+R L + R I + D ++ + V D+ND P F +Y+
Sbjct: 2431 IDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGRRAFSTLTLSVIDINDKPPFFVLPFYS 2490
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
++ E+ + V ATD D +N + Y + F + P G ++V +L+ +
Sbjct: 2491 TSISESAKEGDTVMMVSATDDD--ENDTIEYSLLDGSESQFFSVHPRQGTITVAKKLEHK 2548
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
LT+ A D+ + + P+F L +AD +
Sbjct: 2549 AGVTLSLTIKATDSANPPHHATTTVEVNIASE-SVKVPRFSNSHYLFSVME-DAD--VGN 2604
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGLP 1230
V + I G+ + F + G ++ SL +RKNQ + +
Sbjct: 2605 VIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIR 2664
Query: 1231 SLSSTAILMVTVADVPDEVEMSDK-PVFISRYYELEIEEN--VNAPVELVSLNLTEHYEN 1287
+ ++ + +T V D +++D P F Y I E+ V V + S + +
Sbjct: 2665 ADAAGGVHAITTVTV-DIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPS 2723
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
++R+ ++ EN F ++ +G L + DRE D Y++I RA
Sbjct: 2724 GRIRFSLVEENP-----YFDLNENSGWLTVASQLDREKIDHYKLIARATD---------- 2768
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
EG D+ + + DVND+ P+F + +P+T+P
Sbjct: 2769 ---------EGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLHLPSTSP 2808
Score = 46.8 bits (106), Expect = 0.005
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLN-ISALDGGNLNDNISVRVFVKDVND 1040
S D + ++ + G+VIV L E+ R+ + + N+ + V + D ND
Sbjct: 1418 SVDDVAMEDKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKSFATFSVNINDEND 1477
Query: 1041 HFPVFK-KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT 1099
+ P F T + F V+E+ VL V A D D G+N +TY I + + F+I +
Sbjct: 1478 NSPYFVGHTAFAF-VDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKS 1536
Query: 1100 GVLSVNGELDRETED-KYILTVVARDN 1125
G + + LD E + + IL + A D+
Sbjct: 1537 GEVRLAKPLDPELQHVESILRIRAIDS 1563
Score = 46.8 bits (106), Expect = 0.005
Identities = 40/158 (25%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
T+ Y L+ G++ + FS+ G++ + K+L EH T L ++A+ NP A
Sbjct: 2516 TIEYSLLDGSESQFFSVHPRQGTITVAKKL----EHKAGV-TLSLTIKATDSANPPHHAT 2570
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY----QL 345
VE+ + + +P F Y S++E+ G + +V + + E FT +
Sbjct: 2571 TTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEI-RFTIVPGSEE 2629
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
D FS++ +G + V++ LDRE + +M + A
Sbjct: 2630 SDSFLPFSVERSTGKIIVKSS--LDRERKNQWKMTIRA 2665
Score = 46.0 bits (104), Expect = 0.008
Identities = 28/86 (32%), Positives = 45/86 (52%)
Query: 259 LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN 318
L + A+ N + +V AS K A+ V IE+LD ND+ P F + + +
Sbjct: 445 LRVSAKINRSERVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVI 504
Query: 319 LPNGFSVLQVMATDKDQGENGEFTYQ 344
G +++V ATD+D+GENG+ Y+
Sbjct: 505 GKPGDVLVKVDATDQDEGENGKIVYK 530
Score = 44.8 bits (101), Expect = 0.018
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ-------VMATDKDQGENGEFT 342
A+V +++ N + P F Y +I EN+P G SVL V A D+D G NG
Sbjct: 1669 AKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVG 1728
Query: 343 YQLDDPKG--AFSIDPRSGWLTVRNQTVLDRE 372
Y++ PK FS+D SG +R Q D E
Sbjct: 1729 YRMLSPKDEQMFSVDQYSG--AIRTQMSFDFE 1758
Score = 44.4 bits (100), Expect = 0.024
Identities = 32/144 (22%), Positives = 73/144 (50%), Gaps = 13/144 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y ++SGN+ LF +D+ +G + L K LD + +H +++ +L+++
Sbjct: 1504 VTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQH-VES---ILRIR 1559
Query: 278 ASQLNNPLKTAQARVEIELLDLND--NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A +++ + + + + + + N+ +F+ Y ++ ++ G VL + A
Sbjct: 1560 A--IDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNAL---- 1613
Query: 336 GENGEFTYQLDDPKGAFSIDPRSG 359
+G +Y+L+ F + SG
Sbjct: 1614 -HHGTVSYKLEPNCTFFEVHTLSG 1636
Score = 41.5 bits (93), Expect = 0.17
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 290 ARVEIELLDLNDNLPEFEV--DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
AR+ + ++D ND P F V Y I ++L +VL+V A+D D G N + L +
Sbjct: 137 ARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSLVN 196
Query: 348 PKGAFSIDPRSGWL 361
F ++P +GW+
Sbjct: 197 RSHDFIVEPVTGWV 210
Score = 39.9 bits (89), Expect = 0.53
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 13/143 (9%)
Query: 994 INERHGHVIVARSLPPES--EFRLNISALDGGN-LNDNISVRVFVKDVNDHFPVFKKTWY 1050
I+ G V + L E ++ L + A G ++ V ++DVND P F ++
Sbjct: 2246 IHPETGDVTITGQLDYEKTQKYDLKLVATSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDV 2305
Query: 1051 NFNVEEAQYTRRVLGKVDATDADF-----GQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+ + ++ T + + + ATD D ++ L Y I D L F ISP TG LS+
Sbjct: 2306 SAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGDETL-FNISPATGELSLA 2364
Query: 1106 GELDRE---TED-KYILTVVARD 1124
++++ ED K +L V D
Sbjct: 2365 RPVEQDDLVNEDTKKVLNVSVTD 2387
Score = 38.7 bits (86), Expect = 1.2
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L + + + ++D ND +PVF V YE + + + + + +V+A D D+G N + +
Sbjct: 133 LETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYF 192
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQ 541
L S+ F + P TG V + G+++L V++ D+
Sbjct: 193 SLVNRSH-----DFIVEPVTGWVRSLRH-VKPGKYSLKVKSEDR 230
Score = 36.3 bits (80), Expect = 6.5
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F+++S NG + + + +D + + + L+V A P ++A +EI + D ND+
Sbjct: 3249 FAINS-NGDVLISQSIDYE-----KIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHA 3302
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLD-DPKGAFSIDPRSGWL 361
P F+ + E G +L+ +D D +NG FT ++ D +F ++ + L
Sbjct: 3303 PTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELL 3362
Query: 362 TVR 364
T +
Sbjct: 3363 TAK 3365
Score = 35.9 bits (79), Expect = 8.6
Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 10/122 (8%)
Query: 1039 NDHFPVFKKTWYNFNVEEAQYT-RRVLGK------VDATDADFGQNANLTY-FIQPSDTD 1090
N H P+F++ Y + E T VL K V A D D G N + Y + P D
Sbjct: 1679 NQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQ 1738
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSP 1149
+ F + +G + D E +Y V A D G D ND P
Sbjct: 1739 M-FSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPP 1797
Query: 1150 KF 1151
+F
Sbjct: 1798 RF 1799
>UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Danio
rerio|Rep: protocadherin 1 gamma 1 - Danio rerio
Length = 932
Score = 113 bits (273), Expect = 3e-23
Identities = 120/475 (25%), Positives = 197/475 (41%), Gaps = 33/475 (6%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
+ E+ E + N+ + + D NDN PVF P + + A G+ + +A D D+G
Sbjct: 102 HFEFILENPLELHNIALEVQDVNDNPPVF-PKGSIKLEISEGAPTGSKLQLTRARDLDVG 160
Query: 491 QNGMVLYDLQRTSNLTI-TSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR 549
N + Y L + + + T K + + G H+L + A D P+
Sbjct: 161 INSVQTYILSQNKHFVLDTKSSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGT 220
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
+ VV I++ + P F Y + N +GTSV +I D E ++
Sbjct: 221 VVIEVVVIDM-------NDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEGANGEIK 273
Query: 608 YDLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y + H + F ++E G I+V+ L Y+ E V ++ + + +
Sbjct: 274 YYINHLSDNTKQLFKIDENYGEISVIGQLDHEKASSYEVE-VQAEDGGGQTGHCKVVIEI 332
Query: 667 VDVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
DVND V+ +K + I + + G I I N+ + I+
Sbjct: 333 DDVNDNAPVISVKSLKNKI---PENTTPGTEIAVI---NVKDQDSGENSRISCSISPNLP 386
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I + T LDRE+ D Y +T+IA + G+ + I + D NDN P
Sbjct: 387 FQLQPYIKSYFILTTSSSLDREQIDNYNVTIIAT-DGGIPPLFSNISLNIQVSDVNDNSP 445
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEM---FDV 839
FE +Y +I EN + GT + + A D D N +Y+L G M +
Sbjct: 446 RFELHSYFIYISENKQAGTSVCS---VSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSI 502
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+ +TGV+ + S D E+ + + +VARD G LSS + + I DENDN P+
Sbjct: 503 NGDTGVIHTV-RSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQ 556
Score = 95.5 bits (227), Expect = 1e-17
Identities = 132/567 (23%), Positives = 224/567 (39%), Gaps = 39/567 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V +EV ++D NDN P+F LY + N+ +GT + K+ A D D G NG + Y +
Sbjct: 221 VVIEVVVIDMNDNAPLF-SQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHL 279
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S+ T FKI+ N G +SV L+ A E Q A + V IE+
Sbjct: 280 SDNT-KQLFKIDENYGEISVIGQ--LDHEKASSYEVEVQ-AEDGGGQTGHCKVVIEID-D 334
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P I + + N GT + I V D + + + + +PF +
Sbjct: 335 VNDNAPVI---SVKSLKNKIPENTTPGTEIAVINVKD--QDSGENSRISCSISPNLPFQL 389
Query: 623 E---ERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLK 678
+ + ++T L R Y+ +A L + + V DVND
Sbjct: 390 QPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRF-- 447
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA--NQQDVTDDIAIAED- 735
HS I+ + AG ++ + N NGT + + N ++ ++I D
Sbjct: 448 ELHSYFIYISENKQAGTSVCSV-SANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDT 506
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I T + D E+ + + V+A N + + V ++I DENDN P + +G
Sbjct: 507 GVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNV-TVKVFITDENDNSPQILYPVPDGK 565
Query: 796 IMENSKIGTEIKMDNIIK---ATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGD 851
+ + +++ A DAD G NA Y + +F + ++G +K D
Sbjct: 566 SLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRD 625
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI---EENSKVRIHR 906
+ + L + +D G LS+ + ++I D PE + + NSK+ +
Sbjct: 626 -ISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVPELKDMSYEDNNSKLTSYL 684
Query: 907 ETKLNGTAGF--TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNG 964
L F T I + KF + P L + + + + N D+D G
Sbjct: 685 IIALVSVCAFFLTFIIMMLAVKFC---HRRKPRLLFDGAVAVPSAYLPPNYADVDGA--G 739
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRY 991
+R +N + Y+ ++D V Y
Sbjct: 740 TLRSSYNYDAYLTTGSRTSDFKFVSSY 766
Score = 84.2 bits (199), Expect = 2e-14
Identities = 111/416 (26%), Positives = 172/416 (41%), Gaps = 45/416 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E P G+ + A DLD G+N Y + + L+ K +R+
Sbjct: 139 ISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHF--------VLDTKSS---KDRYV 187
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDN--ISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ SL E+ E L +SA+DGGN ++ + + V V D+ND+ P+F + YN +
Sbjct: 188 DIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLS 247
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + K+ ATD D G N + Y+I +T F+I G +SV G+LD E
Sbjct: 248 ENSALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQLDHEKA 307
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y + V A D G DVNDN+P + L+ K PE +
Sbjct: 308 SSYEVEVQAEDGG---GQTGHCKVVIEIDDVNDNAPVISV--KSLKNKIPE----NTTPG 358
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILYSLPQRKNQQNL----- 1227
+ +I V EN+ I +++ +I + L S R+ N
Sbjct: 359 TEIAVINVKDQDSGENSRISCSISPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTII 418
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL--VSLNL 1281
G+P L S L + V+DV D + P F Y + I EN A + VS N
Sbjct: 419 ATDGGIPPLFSNISLNIQVSDVND-----NSPRFELHSYFIYISENKQAGTSVCSVSAND 473
Query: 1282 TEHYENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ +N + Y ++ N + I+ G ++ VRS D E + V V A
Sbjct: 474 PDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVA 529
Score = 79.0 bits (186), Expect = 9e-13
Identities = 56/173 (32%), Positives = 91/173 (52%), Gaps = 15/173 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT---FVLQV 276
A D D+G+ + Y ++S N K F LD+ + ++ +D+ +++L T L +
Sbjct: 154 ARDLDVGINSVQTY-ILSQN--KHFVLDTKSSK---DRYVDIVLKNSLDRETRGEHSLIL 207
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A NP + +E+ ++D+NDN P F YN + EN G SV+++ ATD+D+G
Sbjct: 208 SAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEG 267
Query: 337 ENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NGE Y + D+ K F ID G ++V Q LD E SS ++V A++
Sbjct: 268 ANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQ--LDHEKASSYEVEVQAED 318
Score = 77.8 bits (183), Expect = 2e-12
Identities = 99/338 (29%), Positives = 147/338 (43%), Gaps = 42/338 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN GT I +N D DSG N +I + + P +L +K YF++
Sbjct: 351 IPENTTPGTEIAVINVKDQDSGENSRISCSISPNL---PFQLQP---YIKSYFILT---- 400
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ SL E + + I A DGG L NIS+ + V DVND+ P F+ Y +
Sbjct: 401 ---TSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYIS 457
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP----FEISPLTGVLSVNGELDR 1110
E + + V A D D+ QN + Y + PS+ + +P I+ TGV+ D
Sbjct: 458 ENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDY 517
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK-FYAFDE---LLEWKHPEAD 1166
E + + VVARDNG D NDNSP+ Y + L+ P+A
Sbjct: 518 EQFRNFSVKVVARDNG-SPPLSSNVTVKVFITDENDNSPQILYPVPDGKSLMTEMVPKA- 575
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI--LYSLPQRKN- 1223
LS V+ + A +NA + + K IG +G I + + N
Sbjct: 576 TLSGSLVSKVIAV---DADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNM 632
Query: 1224 QQNL-------GLPSLSSTAILMVTVADVPDEV-EMSD 1253
+QNL G PSLS+T ++ + ++D EV E+ D
Sbjct: 633 KQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVPELKD 670
Score = 64.1 bits (149), Expect = 3e-08
Identities = 45/171 (26%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A D+D G ++Y + +S N ++LF +D G + + +LD + +A+++ ++
Sbjct: 259 ITATDEDEGANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQLDHE-----KASSYEVE 313
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA +T +V IE+ D+NDN P V I EN G + + D+D
Sbjct: 314 VQAEDGGG--QTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDS 371
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
GEN + + P F + P + + + LDRE + + + A +
Sbjct: 372 GENSRISCSI-SPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATD 421
Score = 63.3 bits (147), Expect = 5e-08
Identities = 47/175 (26%), Positives = 88/175 (50%), Gaps = 11/175 (6%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G +F + +DRE I F + + ++ + + ++D NDNPPVF + +
Sbjct: 77 DSGDLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKGSIK 136
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG--- 850
I E + G++++ + +A D D G N++ Y L + K F +D + +++
Sbjct: 137 LEISEGAPTGSKLQ---LTRARDLDVGINSVQTYIL-SQNKH-FVLDTKSSKDRYVDIVL 191
Query: 851 -DSLDREKKIMYKLSLVARDTGGLSSEAELII--MIGDENDNKPEFNQIEENSKV 902
+SLDRE + + L L A D G + ++I ++ D NDN P F+Q N+++
Sbjct: 192 KNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARL 246
Score = 62.1 bits (144), Expect = 1e-07
Identities = 60/235 (25%), Positives = 105/235 (44%), Gaps = 10/235 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S +++ + + D NDN+P F + Y + N + GT + V A DPD QNG VLY
Sbjct: 427 LFSNISLNIQVSDVNDNSPRF-ELHSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYS 485
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAV 554
L + + ++S IN +TG + S E ++ V A D + P ++ V
Sbjct: 486 LVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKV 545
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLLH 612
+ + +PD E + + G+ V ++ DA QN +SY +L
Sbjct: 546 FITDENDNSPQILYPVPDGKSLMTEMVPKATLS-GSLVSKVIAVDADSGQNAWLSYQILK 604
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
+ G+ F + SG I D+S + M +++++N S+ T V+++
Sbjct: 605 STDPGL-FTIGLHSGEIKTQRDISESDN-MKQNLVISVKDNGQPSLSTTCVVNLL 657
Score = 50.4 bits (115), Expect = 4e-04
Identities = 48/151 (31%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQV 276
I+ DQD G + + IS N F L S F L LD E Q + + + +
Sbjct: 364 INVKDQDSGENSRISCS-ISPN--LPFQLQPYIKSYFILTTSSSLDRE---QIDNYNVTI 417
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ P + + I++ D+NDN P FE+ Y I I EN G SV V A D D
Sbjct: 418 IATDGGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWR 477
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQT 367
+NG Y L P + P S +L++ T
Sbjct: 478 QNGTVLYSL-VPSEVNGV-PMSSFLSINGDT 506
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/158 (27%), Positives = 71/158 (44%), Gaps = 9/158 (5%)
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
DR+ +D +G LF+ + +D + A+ ++ + L NPL+ +E++ D+
Sbjct: 68 DRRYCEIDLDSGDLFVSERIDREMLCGT-ASPCIMHFEFI-LENPLELHNIALEVQ--DV 123
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
NDN P F + I E P G + A D D G N TY L K F +D +S
Sbjct: 124 NDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNK-HFVLDTKSS 182
Query: 360 ---WLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
++ + + LDRE + + A + NP GT
Sbjct: 183 KDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGT 220
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 27/153 (17%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P S T ++ V V D+ D P+F Y + EN ++ + T+ E
Sbjct: 213 GNPPNSGTVVIEVVVIDMNDNA-----PLFSQPLYNARLSENSALGTSVIKITATDEDEG 267
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N +++YYI + +D + ++ F ID G + ++ D E +YEV V+AE
Sbjct: 268 ANGEIKYYINHLSD-NTKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDG------- 319
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
G T + KVV+ I DVNDN+P
Sbjct: 320 -----------GGQTGH-CKVVIEIDDVNDNAP 340
Score = 44.4 bits (100), Expect = 0.024
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSD 1088
++ + V+DVND+ PVF K + E T L A D D G N+ TY + Q
Sbjct: 115 NIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKH 174
Query: 1089 TDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
L + S V + + LDRET ++ L + A D G D+NDN
Sbjct: 175 FVLDTKSSKDRYVDIVLKNSLDRETRGEHSLILSAVDGG-NPPNSGTVVIEVVVIDMNDN 233
Query: 1148 SPKF 1151
+P F
Sbjct: 234 APLF 237
Score = 43.2 bits (97), Expect = 0.056
Identities = 74/310 (23%), Positives = 124/310 (40%), Gaps = 42/310 (13%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI------------APIG 125
+ + V + I+DVNDN P+ + E T G + + + I
Sbjct: 323 TGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSIS 382
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
P+L L P + F + D+ N +V + D G L S+ + L
Sbjct: 383 PNLPFQLQ-PYIKSYFILTTSSSLDREQIDNYNV---TIIATDGGIPPLFSN---ISLNI 435
Query: 186 KVLDYDAGDKEFQL----VIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISG--N 239
+V D + F+L + ++ K+ + + A D D T+ Y L+ N
Sbjct: 436 QVSDVNDNSPRFELHSYFIYISENKQAGTSVC---SVSANDPDWRQNGTVLYSLVPSEVN 492
Query: 240 DRKLFSLDSVNGSL-FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+ S S+NG + D E Q F ++V A +P ++ V++ + D
Sbjct: 493 GVPMSSFLSINGDTGVIHTVRSFDYE---QFRNFSVKVVARDNGSPPLSSNVTVKVFITD 549
Query: 299 LNDNLPE--FEVDFYNISIVENLP----NGFSVLQVMATDKDQGENGEFTYQL---DDPK 349
NDN P+ + V + E +P +G V +V+A D D G+N +YQ+ DP
Sbjct: 550 ENDNSPQILYPVPDGKSLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTDP- 608
Query: 350 GAFSIDPRSG 359
G F+I SG
Sbjct: 609 GLFTIGLHSG 618
>UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 13
SCAF14555, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1382
Score = 113 bits (272), Expect = 4e-23
Identities = 81/247 (32%), Positives = 127/247 (51%), Gaps = 25/247 (10%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFN-------KGVISGAGIYQVTIYIEDENDNPPV 786
E G I+T+ DRE R Y + V +E K + V ++I D NDN PV
Sbjct: 64 ELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPV 123
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGV 845
F YE + E++ +G + + ATD DEG NA Y + K +FD++ G
Sbjct: 124 FAQRLYEVGVDEDADVGLAVVT---VSATDEDEGANAKLRYQITSGNKGGVFDIEPEVGT 180
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+ F+ LD E++ YKL ++A D G A +++ + ++ND P F+ E V
Sbjct: 181 I-FVAQPLDYEQQKRYKLLVLASD-GRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVT-- 236
Query: 906 RETKLNGTAGFTIIEVKPKN----KFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
+L+G+ F ++++ +N +FA L PL PE++P+GT+II++ A D DSG
Sbjct: 237 --EELDGSPVF-VLQIDDENDNAPEFASSSHLLPPL---PEDVPVGTSIIQVVATDTDSG 290
Query: 962 LNGQIRY 968
LNG+I Y
Sbjct: 291 LNGEILY 297
Score = 98.7 bits (235), Expect = 1e-18
Identities = 96/337 (28%), Positives = 145/337 (43%), Gaps = 30/337 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA----LEVKRYFVIN 995
+ E IGT++++++A D D GLNGQI Y S+ S D + + F
Sbjct: 18 VTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFRIDPELGIIYTEAVFDRE 77
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
R +++ +S + R + +D VRVF+ DVND+ PVF + Y V+
Sbjct: 78 ARSSYLLEVQSEDGQESARPGKNKQPN---SDTAYVRVFISDVNDNKPVFAQRLYEVGVD 134
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + V ATD D G NA L Y I + F+I P G + V LD E + +
Sbjct: 135 EDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPEVGTIFVAQPLDYEQQKR 194
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD--------- 1166
Y L V+A D + ND +P F + +E E D
Sbjct: 195 YKLLVLASDG----RWEDYAAIVVTVVNKNDEAPVF-SMNEYYGSVTEELDGSPVFVLQI 249
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS-LPQRKNQQ 1225
+ N N + E+ P+GT++ +V A DTD NG ILYS LPQ
Sbjct: 250 DDENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTD--SGLNGEILYSILPQSDPHG 307
Query: 1226 NL---GLPSLSSTAILMVTVADVPD---EVEMSDKPV 1256
+ G P+L+++ + + + D D E+E + PV
Sbjct: 308 HFATAGTPALTASVTVHLLLLDTNDNGPELETAYAPV 344
Score = 91.1 bits (216), Expect = 2e-16
Identities = 83/294 (28%), Positives = 133/294 (45%), Gaps = 37/294 (12%)
Query: 218 IHAIDQDLGVGATLRYELISGN--DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+DLG+ + Y L+S + D LF +D G ++ E D +A ++++L+
Sbjct: 31 VSAHDKDLGLNGQITYTLLSDSSGDHSLFRIDPELGIIYTEAVFDREAR-----SSYLLE 85
Query: 276 VQAS---QLNNPLKTAQ-----ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
VQ+ + P K Q A V + + D+NDN P F Y + + E+ G +V+
Sbjct: 86 VQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPVFAQRLYEVGVDEDADVGLAVVT 145
Query: 328 VMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
V ATD+D+G N + YQ+ + G F I+P G + V LD E ++ V A +
Sbjct: 146 VSATDEDEGANAKLRYQITSGNKGGVFDIEPEVGTIFVAQP--LDYEQQKRYKLLVLASD 203
Query: 386 TNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNV 445
G + D I N E + + G+ TE + D + + +
Sbjct: 204 ------GRWEDYAAIV-----VTVVNKNDEAPVFSMNEYYGSVTEEL---DGSPVFVLQI 249
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ D NDN P F S+ + + VGT I +V A D D G NG +LY +
Sbjct: 250 D----DENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTDSGLNGEILYSI 299
Score = 75.4 bits (177), Expect = 1e-11
Identities = 112/463 (24%), Positives = 187/463 (40%), Gaps = 41/463 (8%)
Query: 451 DANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP 510
D NDN P F S++YE S+ A++GT + +V A D DLG NG + Y L S+ S
Sbjct: 1 DVNDNVPFFT-SSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSS-GDHSL 58
Query: 511 FKINPNTGTVSVAESPILEGRHALFVEA-------SDQPANPSERRYSLAVVTIEVTRGT 563
F+I+P G + E R + +E S +P + A V + ++
Sbjct: 59 FRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFIS-DV 117
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFA 621
NK P F YE V + +G +V + D E + Y + G + GV F
Sbjct: 118 NDNK---PVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGV-FD 173
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+E G I V L + Y + + L + V VV+ NDE V +
Sbjct: 174 IEPEVGTIFVAQPLDYEQQKRY--KLLVLASDGRWEDYAAIVVTVVNKNDEAPVF---SM 228
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ V E G+ + + + + + L +DV +I + T
Sbjct: 229 NEYYGSVTEELDGSPVFVLQIDDENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTD 288
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT------IYIEDENDNPPVFEHATYEGF 795
L+ E +Y + ++ G + AG +T + + D NDN P E A Y
Sbjct: 289 SGLNGE--ILYSILPQSD-PHGHFATAGTPALTASVTVHLLLLDTNDNGPELETA-YAPV 344
Query: 796 IMENSKIGTEI---KMDNIIKATDADEGTNA----LFMYTLFGEGKEMFDVDENTGVVKF 848
+ ENS + + ++ D D N L + +L+ + D + ++
Sbjct: 345 LWENSPAPQVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVDFHLQDHGNGSAMLTA 404
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN 889
+ DRE++ + L ++ D+G +++ L I IGD+NDN
Sbjct: 405 L-RMFDRERQSEFHLPVIMVDSGDPPMTATNTLTITIGDQNDN 446
Score = 67.7 bits (158), Expect = 2e-09
Identities = 41/96 (42%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKG---AFS 353
D+NDN+P F Y S+ E G SVLQV A DKD G NG+ TY L D G F
Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFR 60
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
IDP G + + V DREA SS ++V +++ S
Sbjct: 61 IDPELG--IIYTEAVFDREARSSYLLEVQSEDGQES 94
Score = 66.9 bits (156), Expect = 4e-09
Identities = 52/187 (27%), Positives = 97/187 (51%), Gaps = 24/187 (12%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKM 1290
S TA + V ++DV D +KPVF R YE+ ++E+ + + +V+++ T+ E N K+
Sbjct: 105 SDTAYVRVFISDVND-----NKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKL 159
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER---QKYSRELPHM 1347
RY I + N + F I+P GT+++ + D E + Y+++V A + Y+ + +
Sbjct: 160 RYQITSGNKGGV---FDIEPEVGTIFVAQPLDYEQQKRYKLLVLASDGRWEDYAAIVVTV 216
Query: 1348 IYPVAEDVLEGMTKYDVKV----------VVRIKDVNDNSPKFTNGNRPLVTAIPTTAPF 1397
+ E + M +Y V V++I D NDN+P+F + + L+ +P P
Sbjct: 217 VNKNDEAPVFSMNEYYGSVTEELDGSPVFVLQIDDENDNAPEFASSSH-LLPPLPEDVPV 275
Query: 1398 GYQVMQL 1404
G ++Q+
Sbjct: 276 GTSIIQV 282
Score = 66.5 bits (155), Expect = 5e-09
Identities = 106/500 (21%), Positives = 201/500 (40%), Gaps = 63/500 (12%)
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
D NDN P F + YE + E ++IGT + + A D D G N YTL
Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQ---VSAHDKDLGLNGQITYTL--------- 48
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEE 898
+ +++G +D E I+Y ++ R EA ++ ++++ E + +
Sbjct: 49 LSDSSGDHSLF--RIDPELGIIYTEAVFDR-------EARSSYLLEVQSEDGQESARPGK 99
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDL 958
N + + +T + + KP FA + ++G + E+ +G ++ ++A D
Sbjct: 100 NKQP--NSDTAYVRVFISDVNDNKPV--FAQRLYEVG----VDEDADVGLAVVTVSATDE 151
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNIS 1018
D G N ++RY+ S F I G + VA+ L E + R +
Sbjct: 152 DEGANAKLRYQITSG-------------NKGGVFDIEPEVGTIFVAQPLDYEQQKRYKLL 198
Query: 1019 AL-DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQ 1076
L G D ++ V V + ND PVF Y +V EE + + ++D + + +
Sbjct: 199 VLASDGRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTEELDGSPVFVLQIDDENDNAPE 258
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
A+ ++ + P D+P S + V++ + + E Y + + +G
Sbjct: 259 FASSSHLLPPLPEDVPVGTS-IIQVVATDTDSGLNGEILYSILPQSDPHGHFATAGTPAL 317
Query: 1137 XXXXXX-----DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
D NDN P+ + W++ A ++ N S ++ V + + E P
Sbjct: 318 TASVTVHLLLLDTNDNGPELETAYAPVLWENSPAPQVVWLNQSSTLLHVVDRDSPENGPP 377
Query: 1192 IGTTVAKVFANDTDFIGNGNG---LILYSLPQRKNQQNL---------GLPSLSSTAILM 1239
++ +++ D +GNG L + R+ Q G P +++T L
Sbjct: 378 YYLSLPSLYSVDFHLQDHGNGSAMLTALRMFDRERQSEFHLPVIMVDSGDPPMTATNTLT 437
Query: 1240 VTVADVPDEV-EMSDKPVFI 1258
+T+ D D + +K V++
Sbjct: 438 ITIGDQNDNAHQAGEKDVYV 457
Score = 55.2 bits (127), Expect = 1e-05
Identities = 104/420 (24%), Positives = 167/420 (39%), Gaps = 47/420 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN PVF LYE + +A VG + V A D D G N + Y + +
Sbjct: 110 VRVFISDVNDNKPVFA-QRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNK 168
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F I P GT+ VA+ E R+ L V ASD Y+ VVT+ V +
Sbjct: 169 GGV---FDIEPEVGTIFVAQPLDYEQQKRYKLLVLASD----GRWEDYAAIVVTV-VNKN 220
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ + ++ G+ E GS V + + ND + S LL E VP
Sbjct: 221 DEAPVFSMNEYYGSVTEELDGSPVFVLQIDDE---NDNAPEFASSSHLLPPLPEDVPVGT 277
Query: 623 EERSGVITVVD-----DLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGV 675
V T D ++ P D ++ + TVH ++D ND G
Sbjct: 278 SIIQVVATDTDSGLNGEILYSILPQSDPHG-HFATAGTPALTASVTVHLLLLDTND-NGP 335
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY------GNGTGNVRFLIANQQDVTDD 729
L+ A++P+++ ENS Q+ N SS + + ++ + D
Sbjct: 336 ELETAYAPVLW---ENSPAP---QVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVD 389
Query: 730 IAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ + G + + DRE++ + + VI + G +TI I D+NDN
Sbjct: 390 FHLQDHGNGSAMLTALRMFDRERQSEFHLPVIM-VDSGDPPMTATNTLTITIGDQNDN-- 446
Query: 786 VFEHATYEGFIMENSKIGTEIKMD-NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
H E + +S+ G + A D D+ N YTL + F +++++G
Sbjct: 447 --AHQAGEKDVYVHSRKGRVGNAALGKVYAPDPDDWDNK--TYTLETSAAKYFSLNQSSG 502
Score = 50.0 bits (114), Expect = 5e-04
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 4/64 (6%)
Query: 294 IELLDLNDNLPEFEVDFYNIS-IVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPK 349
+++ D NDN PEF + + + E++P G S++QV+ATD D G NGE Y + DP
Sbjct: 247 LQIDDENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTDSGLNGEILYSILPQSDPH 306
Query: 350 GAFS 353
G F+
Sbjct: 307 GHFA 310
Score = 49.2 bits (112), Expect = 9e-04
Identities = 80/347 (23%), Positives = 137/347 (39%), Gaps = 38/347 (10%)
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYE-EGVPFAVEER 625
++P F + YE V IGTSV Q+ +D ++Y LL + F ++
Sbjct: 5 NVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFRIDPE 64
Query: 626 SGVITVVDDLSRYNRPMYDFEAVAL--QENANL-------SIVTNATVHVVDVNDERGVL 676
G+I R R Y E + QE+A S V + DVND + V
Sbjct: 65 LGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPVF 124
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + + ++ G A+ + T+ N + N+ V D E G
Sbjct: 125 AQRLYEVGVD--EDADVGLAVVTVSATDEDE-GANAKLRYQITSGNKGGVFD--IEPEVG 179
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
TIF +PLD E++ Y++ V+A + A + + + ++ND PVF Y G +
Sbjct: 180 TIFVAQPLDYEQQKRYKLLVLASDGRWEDYAA----IVVTVVNKNDEAPVFSMNEYYGSV 235
Query: 797 MENSKIGTEIKMDNIIKATD-ADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
E G+ + + I D A E ++ + E DV T +++ + D
Sbjct: 236 TEELD-GSPVFVLQIDDENDNAPEFASSSHLLPPLPE-----DVPVGTSIIQVVATDTDS 289
Query: 856 --EKKIMYKL--------SLVARDTGGLSSEAELIIMIGDENDNKPE 892
+I+Y + T L++ + +++ D NDN PE
Sbjct: 290 GLNGEILYSILPQSDPHGHFATAGTPALTASVTVHLLLLDTNDNGPE 336
Score = 41.5 bits (93), Expect = 0.17
Identities = 41/146 (28%), Positives = 61/146 (41%), Gaps = 29/146 (19%)
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI 121
++G + R G S V V+I DVNDN P+F Y V VDE G +
Sbjct: 89 EDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPVFAQRLYEVGVDEDADVG-------L 141
Query: 122 APIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
A + S T D+ N+ + Y I SGN G F +E
Sbjct: 142 AVVTVSAT--------------------DEDEGANAKLRYQITSGNKGGVFDIE-PEVGT 180
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKR 207
+ + + LDY+ K ++L+++AS R
Sbjct: 181 IFVAQPLDYEQ-QKRYKLLVLASDGR 205
Score = 40.7 bits (91), Expect = 0.30
Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 1255 PVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRN 1312
P F S YE + E + V VS + + N ++ Y +L+++ D F IDP
Sbjct: 7 PFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGD-HSLFRIDPEL 65
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
G +Y DRE + +Y + V++E + S P ++ T Y V V I D
Sbjct: 66 GIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSD------TAY---VRVFISD 116
Query: 1373 VNDNSPKF 1380
VNDN P F
Sbjct: 117 VNDNKPVF 124
>UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Rep:
LOC555688 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1078
Score = 113 bits (272), Expect = 4e-23
Identities = 117/456 (25%), Positives = 194/456 (42%), Gaps = 33/456 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-LQR 501
V + + ++D+NDNNPVF +Y ++ N+ + T++ + A DPD G NG V+Y +
Sbjct: 213 VQLNIKVIDSNDNNPVF-DEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFINF 271
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVTI 557
SNLT FKI+P TG ++V + +L+ H + V+A D N + V I
Sbjct: 272 VSNLT-KQMFKIDPKTGVITV--NGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVI 328
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
++ N P+I V N +G + +RV+D + + + +
Sbjct: 329 DI----NDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSD--NDSGANGKVQCRLQGN 382
Query: 618 VPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERG 674
VPF + E T++ D L R R MY+ +A L + V V D ND
Sbjct: 383 VPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAVKVTDENDNPP 442
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ--DVTDDIAI 732
K + ++ EN+ A + NGT + + + + V + +
Sbjct: 443 YFTKPHYQAMVL---ENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTV 499
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE---- 788
+G I+ + + E + V A+ + G V I + D NDN PV
Sbjct: 500 NSNGEIYGVRAFNHEDTRTFEFKVSAK-DGGDPPLTSNATVRIVVLDVNDNTPVMTTPPL 558
Query: 789 -HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ T E I +N+ +G + IKA D DEG N Y++ F++D+ G V+
Sbjct: 559 VNGTAEVSIPKNAGVGYLVTQ---IKADDYDEGENGRLTYSISEGDMAYFEIDQINGEVR 615
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ K Y++++VA D G S A I+I
Sbjct: 616 -TTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVI 650
Score = 101 bits (243), Expect = 1e-19
Identities = 113/470 (24%), Positives = 191/470 (40%), Gaps = 37/470 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
M +++ ++D NDN P F P+N + + NA GT A DPD G NG+ Y +
Sbjct: 101 MEICVIKIEIIDVNDNAPRF-PTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTI 159
Query: 500 QRTSNLTITSPFKINPNTGTVS--VAESPI---LEGRHALFVEASDQPANPSERRYSLAV 554
T N K + ++ V E + + R+ + A D P L +
Sbjct: 160 --TPNDIFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNI 217
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
I+ + + P F Y V N I T V + D E +V Y ++
Sbjct: 218 KVID-------SNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFIN 270
Query: 613 GYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDV 669
F ++ ++GVITV L +++ + A N + V+V+D+
Sbjct: 271 FVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDI 330
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND + + + + V EN+ + + + + NG R Q +V
Sbjct: 331 NDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKVQCRL----QGNVPFR 386
Query: 730 IAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ E T+ LDRE+RD+Y +T++AE + G + + DENDNPP F
Sbjct: 387 LNEFESFSTLLVDGRLDREQRDMYNLTILAE-DSGYPPLRSSKSFAVKVTDENDNPPYFT 445
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-----GEGKEMFDVDENT 843
Y+ ++EN+ G + + A D D G N Y + G E + +
Sbjct: 446 KPHYQAMVLENNVPGAFLL---AVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSN 502
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
G + + + + E ++ + A+D G L+S A + I++ D NDN P
Sbjct: 503 GEIYGV-RAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTP 551
Score = 100 bits (240), Expect = 3e-19
Identities = 82/286 (28%), Positives = 139/286 (48%), Gaps = 25/286 (8%)
Query: 648 VALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
++L+ +N + + ++DVND + + I + EN AA G F +S
Sbjct: 92 ISLEVMSNSMEICVIKIEIIDVNDNAP---RFPTNHIDIEISEN---AAPGTRFPLEGAS 145
Query: 708 IYGNGTGNVRFLIANQQDVTD-DIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNK 762
+G+ ++ D+ +I DG+ + +K LDRE + Y + AE +
Sbjct: 146 DPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAE-DG 204
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G +G Q+ I + D NDN PVF+ Y ++ENS I T + +D + ATD DEGTN
Sbjct: 205 GDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINT-LVID--LNATDPDEGTN 261
Query: 823 ALFMYTLF----GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE 876
+Y+ K+MF +D TGV+ + LD E+ ++++ + A+D G + +
Sbjct: 262 GEVVYSFINFVSNLTKQMFKIDPKTGVIT-VNGVLDHEELHIHEIDVQAKDLGPNSIPAH 320
Query: 877 AELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
++I+ + D NDN PE + ENS++ E N G+ I V+
Sbjct: 321 CKVIVNVIDINDNAPEIKLLSENSEM---VEVSENAPLGYVIALVR 363
Score = 88.6 bits (210), Expect = 1e-15
Identities = 148/542 (27%), Positives = 224/542 (41%), Gaps = 65/542 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT A D DSG NG Y I P+ + LE+K +
Sbjct: 129 ISENAAPGTRFPLEGASDPDSGSNGIQTYT------ITPNDIFG--LEIKTRGD-GSKIA 179
Query: 1000 HVIVARSLPPESEFR--LNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
++V ++L E++ R ++A DGG+ + +V++ +K D ND+ PVF + Y NV
Sbjct: 180 ELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVL 239
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQ--PSDTDLPFEISPLTGVLSVNGELDRET 1112
E ++ ++ATD D G N + Y FI + T F+I P TGV++VNG LD E
Sbjct: 240 ENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEE 299
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ + V A+D G D+NDN+P+ E + E E+S N
Sbjct: 300 LHIHEIDVQAKDLG-PNSIPAHCKVIVNVIDINDNAPEIKLLSE-----NSEMVEVS-EN 352
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFAND----TDFIGNGNGLILYSLP-QRKNQQNL 1227
+I + + + ++ G ++ N +F L+ L ++++ NL
Sbjct: 353 APLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNL 412
Query: 1228 -------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV-NAPVELVSL 1279
G P L S+ V V D D KP Y + +E NV A + VS
Sbjct: 413 TILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKP----HYQAMVLENNVPGAFLLAVSA 468
Query: 1280 NLTEHYENFKMRYYILNENDTDIR-RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ N + Y I+ + ++V NG +Y VR+ + E T+E V A
Sbjct: 469 RDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSA--- 525
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG---NRPLVTAIPTTA 1395
K + P + T V++VV DVNDN+P T N +IP A
Sbjct: 526 KDGGDPP---------LTSNAT---VRIVV--LDVNDNTPVMTTPPLVNGTAEVSIPKNA 571
Query: 1396 PFGYQVMQLKGAIGHHPTASR-TVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRY 1454
GY V Q+K R T ++ +FE +NG T G NA Y
Sbjct: 572 GVGYLVTQIKADDYDEGENGRLTYSISEGDMAYFEIDQING---EVRTTKTFGENAKPSY 628
Query: 1455 QI 1456
QI
Sbjct: 629 QI 630
Score = 75.8 bits (178), Expect = 9e-12
Identities = 59/216 (27%), Positives = 91/216 (42%), Gaps = 20/216 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ N+P G ++ ++A D D G+NG + YE K + V+ Y +N +
Sbjct: 453 VLENNVP-GAFLLAVSARDPDLGMNGTVSYEI--------IKSEVRGMSVESYVTVNS-N 502
Query: 999 GHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + R+ E F +SA DGG+ L N +VR+ V DVND+ PV
Sbjct: 503 GEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGT 562
Query: 1055 EEAQYTRR-----VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
E + ++ ++ A D D G+N LTY I D FEI + G +
Sbjct: 563 AEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGDMAY-FEIDQINGEVRTTKTFG 621
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ Y +TVVA D+G D+N
Sbjct: 622 ENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLN 657
Score = 75.4 bits (177), Expect = 1e-11
Identities = 54/181 (29%), Positives = 86/181 (47%), Gaps = 16/181 (8%)
Query: 220 AIDQDLGVGATLRYEL----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
A D D G Y + I G + K S L +EK LD + + + + +
Sbjct: 144 ASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELVVEKTLDRETQ-----SRYTFE 198
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A +P K+ ++ I+++D NDN P F+ Y ++++EN P V+ + ATD D+
Sbjct: 199 LTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDE 258
Query: 336 GENGEFTYQLDD-----PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
G NGE Y + K F IDP++G +TV VLD E + V AK+ P+
Sbjct: 259 GTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNG--VLDHEELHIHEIDVQAKDLGPNS 316
Query: 391 V 391
+
Sbjct: 317 I 317
Score = 74.1 bits (174), Expect = 3e-11
Identities = 84/329 (25%), Positives = 131/329 (39%), Gaps = 21/329 (6%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVP---IFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
G N I A+ V V + D+NDN P + + V V E P G + ++
Sbjct: 313 GPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSGAN 372
Query: 130 ------IPLTVPRGLTIFKDIRAFDRD-KPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
+ VP L F+ D + + D++ + D G+ L SS +
Sbjct: 373 GKVQCRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAV 432
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK 242
+ D + M + L + A D DLG+ T+ YE+I R
Sbjct: 433 KVTDENDNPPYFTKPHYQAMVLENNVPGAFLLA--VSARDPDLGMNGTVSYEIIKSEVRG 490
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+ S++S + + A ++ TF +V A +P T+ A V I +LD+NDN
Sbjct: 491 M-SVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDN 549
Query: 303 LPEFEVD-----FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-FSIDP 356
P +SI +N G+ V Q+ A D D+GENG TY + + A F ID
Sbjct: 550 TPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGDMAYFEIDQ 609
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G VR A S ++ V A +
Sbjct: 610 ING--EVRTTKTFGENAKPSYQITVVAHD 636
Score = 60.9 bits (141), Expect = 3e-07
Identities = 56/231 (24%), Positives = 96/231 (41%), Gaps = 11/231 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + V + D NDN P F + Y+ + N G + V A DPDLG NG V Y+
Sbjct: 424 LRSSKSFAVKVTDENDNPPYFTKPH-YQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYE 482
Query: 499 LQRTS--NLTITSPFKINPNTGTVSVAESPILEGRHALF-VEASDQPANPSERRYSLAVV 555
+ ++ +++ S +N N V + R F V A D P ++ +V
Sbjct: 483 IIKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIV 542
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHG 613
++V T P + E + N G+G V QI+ + D E ++Y + G
Sbjct: 543 VLDVNDNTP--VMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEG 600
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
+ F +++ +G + +P Y VA ++ S+ +A +
Sbjct: 601 --DMAYFEIDQINGEVRTTKTFGENAKPSYQITVVA-HDHGQTSLSASAYI 648
Score = 58.4 bits (135), Expect = 1e-06
Identities = 44/175 (25%), Positives = 79/175 (45%), Gaps = 12/175 (6%)
Query: 218 IHAIDQDLGVGATLRYELI---SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y I S +++F +D G + + LD + H + +
Sbjct: 251 LNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHE-----I 305
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN---ISIVENLPNGFSVLQVMAT 331
VQA L A +V + ++D+NDN PE ++ N + + EN P G+ + V +
Sbjct: 306 DVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVS 365
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
D D G NG+ +L F ++ + T+ LDRE + + A+++
Sbjct: 366 DNDSGANGKVQCRLQG-NVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDS 419
Score = 58.0 bits (134), Expect = 2e-06
Identities = 67/274 (24%), Positives = 116/274 (42%), Gaps = 15/274 (5%)
Query: 629 ITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
+ V L R + Y FE A + S + V+D ND V + ++ +
Sbjct: 181 LVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYT---VN 237
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDDIAIAED--GTIFTQKPL 744
V ENS + + N + G V + N ++T + + G I L
Sbjct: 238 VLENSPINTL--VIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVL 295
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
D E+ ++ + V A+ + G S +V + + D NDN P + + ++E S+
Sbjct: 296 DHEELHIHEIDVQAK-DLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAP 354
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS-LDREKKIMYKL 863
+ +++ +D D G N L +G F ++E + D LDRE++ MY L
Sbjct: 355 LGYVIALVRVSDNDSGANGKVQCRL--QGNVPFRLNEFESFSTLLVDGRLDREQRDMYNL 412
Query: 864 SLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+++A D+G L S + + DENDN P F +
Sbjct: 413 TILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTK 446
Score = 48.4 bits (110), Expect = 0.002
Identities = 45/165 (27%), Positives = 76/165 (46%), Gaps = 13/165 (7%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+IS ++ + +L S G L ++++D DA F+ ++N ++ ++I
Sbjct: 55 VISNSEPRWVNL-SPAGLLITKQKIDRDAVCRQTPKCFI---SLEVMSNSMEICV--IKI 108
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
E++D+NDN P F + +I I EN G A+D D G NG TY + P F +
Sbjct: 109 EIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTI-TPNDIFGL 167
Query: 355 D--PRSGWLTVRNQTV---LDREAHSSLRMKVYAKE-TNPSVVGT 393
+ R + V LDRE S ++ A++ +P GT
Sbjct: 168 EIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGT 212
Score = 47.2 bits (107), Expect = 0.003
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLY----EFSMKSNAKVGTVIGKVKAVDPDLGQ 491
D L S V + +LD NDN PV L E S+ NA VG ++ ++KA D D G+
Sbjct: 530 DPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGE 589
Query: 492 NGMVLYDL 499
NG + Y +
Sbjct: 590 NGRLTYSI 597
>UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31;
Euteleostomi|Rep: Protocadherin-19 precursor - Homo
sapiens (Human)
Length = 1148
Score = 113 bits (272), Expect = 4e-23
Identities = 120/463 (25%), Positives = 204/463 (44%), Gaps = 32/463 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + V + + + D+NDNNPVF S Y S+ N+ T + ++ A DPD G NG V
Sbjct: 215 DPPRLGTVGLSIKVTDSNDNNPVFSEST-YAVSVPENSPPNTPVIRLNASDPDEGTNGQV 273
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
+Y N F+I+P++G V+V + E H L V+A D N +
Sbjct: 274 VYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVT 333
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V ++ T N P I + + E V + G + +RV+D + ++ +
Sbjct: 334 VSVLD----TNDNPPVI-NLLSVNSELVEVSESAPPGYVIALVRVSD--RDSGLNGRVQC 386
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNA---TVHVVD 668
VPF ++E T++ D R +R +D + +Q + + ++ +A TV + D
Sbjct: 387 RLLGNVPFRLQEYESFSTILVD-GRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITD 445
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--V 726
ND K + I V+EN+ A + NG+ + + + + +D V
Sbjct: 446 ENDNHPHFSKPYYQVI---VQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPV 502
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
++I G I+ + + E+ + V+A+ + G+ S V + I D NDN P
Sbjct: 503 FTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAK-DGGLPSLQSNATVRVIILDVNDNTP 561
Query: 786 VFE-----HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
V + T E +I NS IG + ++KA D DEG N Y + + F++D
Sbjct: 562 VITAPPLINGTAEVYIPRNSGIGYLV---TVVKAEDYDEGENGRVTYDMTEGDRGFFEID 618
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ G V+ + K Y+L +VA D G S A +++I
Sbjct: 619 QVNGEVR-TTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660
Score = 94.7 bits (225), Expect = 2e-17
Identities = 118/470 (25%), Positives = 191/470 (40%), Gaps = 36/470 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
M ++V + D NDN P F P+ E + A GT I A DPD G G+ Y+L
Sbjct: 110 MEICVIKVEIKDLNDNAPSF-PAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYEL 168
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVT 556
+ + + + V E + + ++ + A D P R ++
Sbjct: 169 TPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPP---RLGTVGLS 225
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY 614
I+VT N P F + Y V N T V ++ +D E V Y +GY
Sbjct: 226 IKVTDSNDNN----PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYS-FYGY 280
Query: 615 EEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVN 670
F ++ SG++TV L +Y+ + A N + TV V+D N
Sbjct: 281 VNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTN 340
Query: 671 DERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D V+ L +S ++ V E++ + + + NG R L+ N +
Sbjct: 341 DNPPVINLLSVNSELV-EVSESAPPGYVIALVRVSDRDSGLNGRVQCR-LLGNVPFRLQE 398
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
TI LDRE+ D Y +T+ A + GV T+ I DENDN P F
Sbjct: 399 --YESFSTILVDGRLDREQHDQYNLTIQAR-DGGVPMLQSAKSFTVLITDENDNHPHFSK 455
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEM-----FDVDENT 843
Y+ + EN+ G + + A D D G N Y + + ++M ++ N+
Sbjct: 456 PYYQVIVQENNTPGAYLLS---VSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNS 512
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
G + + S + E+ ++ ++A+D G L S A + ++I D NDN P
Sbjct: 513 GDI-YALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTP 561
Score = 91.1 bits (216), Expect = 2e-16
Identities = 115/417 (27%), Positives = 173/417 (41%), Gaps = 40/417 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P T +I+LNA D D G NGQ+ Y F Y+ + F I+ G
Sbjct: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYG--YVND--------RTRELFQIDPHSG 296
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYN---F 1052
V V +L E + L++ A D G ++ + V V V D ND+ PV N
Sbjct: 297 LVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELV 356
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT--GVLSVNGELDR 1110
V E+ V+ V +D D G N + + ++PF + + V+G LDR
Sbjct: 357 EVSESAPPGYVIALVRVSDRDSGLNGRVQCRLL---GNVPFRLQEYESFSTILVDGRLDR 413
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKHPEADE 1167
E D+Y LT+ ARD G D NDN P F Y + E P A
Sbjct: 414 EQHDQYNLTIQARDGG-VPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYL 472
Query: 1168 LS------NHNFESVMMIPVYKATIEENAPIGTTVA-KVFANDTDFIGNGNGLILYSLPQ 1220
LS + + + + + + P+ T V+ + D + + N +
Sbjct: 473 LSVSARDPDLGLNGSVSYQIVPSQVRD-MPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531
Query: 1221 RKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVS 1278
+ ++ GLPSL S A + V + DV D + P I+ E+ I N + V +V
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ EN ++ Y + E D R F ID NG + R+ K +YE+IV A
Sbjct: 592 AEDYDEGENGRVT-YDMTEGD---RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVA 644
Score = 88.6 bits (210), Expect = 1e-15
Identities = 55/171 (32%), Positives = 91/171 (53%), Gaps = 11/171 (6%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ +K LDRE + Y + A + G G ++I + D NDN PVF +TY +
Sbjct: 190 LVVEKSLDRETQSHYSFRITA-LDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVP 248
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFIGDSL 853
ENS T + N A+D DEGTN +Y+ +G +E+F +D ++G+V G +L
Sbjct: 249 ENSPPNTPVIRLN---ASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTG-AL 304
Query: 854 DREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
D E+ +Y+L + A+D G + + ++ + + D NDN P N + NS++
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSEL 355
Score = 80.6 bits (190), Expect = 3e-13
Identities = 141/545 (25%), Positives = 225/545 (41%), Gaps = 67/545 (12%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+E+K N A I E GT I +A D DSG G YE + P
Sbjct: 117 VEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYE------LTP 170
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLN--DNISVRVF 1034
++L LE+K R ++V +SL E S + I+ALDGG+ + + +
Sbjct: 171 NELFG--LEIKTRGD-GSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIK 227
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY----FIQPSDTD 1090
V D ND+ PVF ++ Y +V E + +++A+D D G N + Y ++ +
Sbjct: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
L F+I P +G+++V G LD E Y L V A+D G D NDN P
Sbjct: 288 L-FQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLG-PNSIPAHCKVTVSVLDTNDNPPV 345
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND----TDF 1206
LL + E E+S + +I + + + ++ G ++ N ++
Sbjct: 346 I----NLLS-VNSELVEVS-ESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEY 399
Query: 1207 IGNGNGLILYSLPQRKNQQ-NL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFI 1258
L+ L + ++ Q NL G+P L S V + D E + P F
Sbjct: 400 ESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITD-----ENDNHPHFS 454
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIR-RTFV-IDPRNGT 1314
YY++ ++EN L+S++ + N + Y I+ D+ T+V I+P +G
Sbjct: 455 KPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGD 514
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
+Y +RS + E +E V A+ LP + + V+V+ I DVN
Sbjct: 515 IYALRSFNHEQTKAFEFKVLAK----DGGLPSL-----------QSNATVRVI--ILDVN 557
Query: 1375 DNSPKFTNG---NRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRADTD-ELVFFER 1430
DN+P T N IP + GY V +K R T+ + FFE
Sbjct: 558 DNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEI 617
Query: 1431 LSLNG 1435
+NG
Sbjct: 618 DQVNG 622
Score = 73.7 bits (173), Expect = 3e-11
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 18/197 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ EN G ++ ++A D D GLNG + Y+ I PS++ + V Y IN
Sbjct: 461 IVQENNTPGAYLLSVSARDPDLGLNGSVSYQ------IVPSQVRD--MPVFTYVSINPNS 512
Query: 999 GHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + RS E F + A DGG +L N +VRV + DVND+ PV
Sbjct: 513 GDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGT 572
Query: 1055 EEAQYTRR-----VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
E R ++ V A D D G+N +TY + D FEI + G +
Sbjct: 573 AEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGF-FEIDQVNGEVRTTRTFG 631
Query: 1110 RETEDKYILTVVARDNG 1126
++ Y L VVA D+G
Sbjct: 632 ESSKSSYELIVVAHDHG 648
Score = 72.9 bits (171), Expect = 6e-11
Identities = 106/448 (23%), Positives = 177/448 (39%), Gaps = 36/448 (8%)
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP----FKINPNTGTVS 521
++S++ + GTVI V D + G L Q ++ +++ INP++G +
Sbjct: 26 KYSVEEEQRAGTVIANVAK---DAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLL- 81
Query: 522 VAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW 581
V + I R L ++ + S+ + I+V K + P F A E
Sbjct: 82 VTKQKI--DRDLLCRQSPKCIISLEVMSSSMEICVIKVE--IKDLNDNAPSFPAAQIELE 137
Query: 582 VGSNVGIGTSVGQIRVNDAFEQNDVS-----YDLLHGYEEGVPFAVE---ERSGVITVVD 633
+ GT +I ++ A++ + S Y+L G+ R + V
Sbjct: 138 ISEAASPGT---RIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEK 194
Query: 634 DLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
L R + Y F AL + T ++ V D ND V + ++ V ENS
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA---VSVPENS 251
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIAE--DGTIFTQKPLDREKR 749
+ N S G V + D T ++ + G + LD E+
Sbjct: 252 PPNT--PVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEG 309
Query: 750 DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
VY + V A+ + G S +VT+ + D NDNPPV + ++E S+ +
Sbjct: 310 HVYELDVQAK-DLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368
Query: 810 NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
+++ +D D G N L G E+ + + LDRE+ Y L++ ARD
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTI-LVDGRLDREQHDQYNLTIQARD 427
Query: 870 TGG--LSSEAELIIMIGDENDNKPEFNQ 895
G L S ++I DENDN P F++
Sbjct: 428 GGVPMLQSAKSFTVLITDENDNHPHFSK 455
Score = 72.1 bits (169), Expect = 1e-10
Identities = 53/180 (29%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSV---NGSLFLEKELDLDAEHNLQANTFVLQV 276
A D D G YEL +LF L+ +GS F E ++ + Q++ + ++
Sbjct: 153 AYDPDSGSFGVQTYEL---TPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSH-YSFRI 208
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A +P + + I++ D NDN P F Y +S+ EN P V+++ A+D D+G
Sbjct: 209 TALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEG 268
Query: 337 ENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
NG+ Y D + F IDP SG +TV LD E + V AK+ P+ +
Sbjct: 269 TNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTG--ALDYEEGHVYELDVQAKDLGPNSI 326
Score = 66.9 bits (156), Expect = 4e-09
Identities = 89/369 (24%), Positives = 145/369 (39%), Gaps = 36/369 (9%)
Query: 43 LVDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFL 98
L D +V D++EG D+ G N I A+ VTV + D NDN P+
Sbjct: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347
Query: 99 DTPYH---VTVDELTPTGEKAFIFLIAPIGPSLTIPL------TVPRGLTIFKDIRAFDR 149
+ V V E P G + ++ L + VP L ++
Sbjct: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILV 407
Query: 150 D-KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD-YDAGDKEFQLVIMASGKR 207
D + + D + + D G L+S+ +L+ D + K + VI+
Sbjct: 408 DGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNT 467
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELISGN--DRKLFSLDSVN---GSLFLEKELDLD 262
+L + A D DLG+ ++ Y+++ D +F+ S+N G ++ + + +
Sbjct: 468 PGAYLL---SVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHE 524
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD-----FYNISIVE 317
Q F +V A P + A V + +LD+NDN P + I
Sbjct: 525 -----QTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPR 579
Query: 318 NLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
N G+ V V A D D+GENG TY + + +G F ID +G VR + SS
Sbjct: 580 NSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEIDQVNG--EVRTTRTFGESSKSS 637
Query: 377 LRMKVYAKE 385
+ V A +
Sbjct: 638 YELIVVAHD 646
Score = 60.5 bits (140), Expect = 3e-07
Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y ++ R+LF +D +G + + LD + H + L
Sbjct: 260 LNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGH-----VYEL 314
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN---ISIVENLPNGFSVLQVMAT 331
VQA L A +V + +LD NDN P + N + + E+ P G+ + V +
Sbjct: 315 DVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVS 374
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+D G NG +L F + + T+ LDRE H + + A++
Sbjct: 375 DRDSGLNGRVQCRLLG-NVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARD 427
Score = 41.5 bits (93), Expect = 0.17
Identities = 41/175 (23%), Positives = 77/175 (44%), Gaps = 14/175 (8%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQAR 291
+ ++S + L ++ +G L ++++D D + L+V +S + +
Sbjct: 61 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICV------ 114
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
+++E+ DLNDN P F + I E G + A D D G G TY+L P
Sbjct: 115 IKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYEL-TPNEL 173
Query: 352 FSIDPR-----SGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRI 400
F ++ + S + + + LDRE S ++ A + +P +GT S ++
Sbjct: 174 FGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKV 228
Score = 41.5 bits (93), Expect = 0.17
Identities = 35/126 (27%), Positives = 48/126 (38%), Gaps = 7/126 (5%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
++V +KD+ND+ P F + EA + A D D G TY + P++
Sbjct: 115 IKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNEL- 173
Query: 1091 LPFEI-----SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
EI L V LDRET+ Y + A D G D N
Sbjct: 174 FGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGG-DPPRLGTVGLSIKVTDSN 232
Query: 1146 DNSPKF 1151
DN+P F
Sbjct: 233 DNNPVF 238
>UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Rep:
Cadherin 87A precursor - Drosophila melanogaster (Fruit
fly)
Length = 1975
Score = 113 bits (272), Expect = 4e-23
Identities = 119/438 (27%), Positives = 194/438 (44%), Gaps = 47/438 (10%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA--KVGTVIGKVKAVDPDLGQNGMV 495
Q + + + +LD NDN PVF ++Y ++ NA + + +V+A+D D G G V
Sbjct: 1190 QKSATATIHINILDVNDNAPVFT-RDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDV 1248
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSL 552
Y + + + + FK++ +G V A+S L G+H L + A D + + +
Sbjct: 1249 RYIITAGNEMGL---FKLDAQSGIVYPAQS--LSGKHGAYELTISARDTQGSGTMESTTK 1303
Query: 553 AVVTI-EVTRGTKGNKPD--IPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVS 607
A++T+ V R +KP+ IP A E G V + +R ND E VS
Sbjct: 1304 AIITVLRVNR----HKPEFVIPALSNATIEI-PGDIVQPDYLLLTVRAMDNDTEENGKVS 1358
Query: 608 YDLL---HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNAT 663
Y L ++ F ++E +G + L+R NR YD VA N + +
Sbjct: 1359 YHLQVNNRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLS 1418
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V +VD N+ R A +P + ENS G + +I H +S + +++
Sbjct: 1419 VSIVDANENRPE-FPDASNPYKVSINENS-GRDV-KIGHIQAASRSKHNRDIFYYMLLGN 1475
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN---------------KGVISGA 768
+D + G I+T K LDRE+ DVY + ++A K +
Sbjct: 1476 EDGAFYVD-KLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDN 1534
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+ +V I + D NDNPPVFE Y + N+K+G I ++ ATDAD+G NA +
Sbjct: 1535 TVAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAI---TLVNATDADQGKNAKIEFM 1591
Query: 829 LFGEGKEMFDVDENTGVV 846
+ F ++TG +
Sbjct: 1592 IVASNLYKFGATKSTGSI 1609
Score = 101 bits (241), Expect = 2e-19
Identities = 136/542 (25%), Positives = 231/542 (42%), Gaps = 46/542 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + +V V +++ NDN+P F S+ Y F++ N+ GTV GKV+A D D+G G + Y
Sbjct: 1083 LTATADVVVDIINLNDNDPKFSQSDYY-FNVTENSPRGTVAGKVEAHDGDVGVFGEITYT 1141
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVT 556
L +N F I+ TG V VA S IL+ L + Q P+ + S A T
Sbjct: 1142 LIGENN----KYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKS-ATAT 1196
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-----DVSYDLL 611
I + + P F Y V N ++V A +Q+ DV Y +
Sbjct: 1197 IHI--NILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQV-QAIDQDEGLYGDVRYIIT 1253
Query: 612 HGYEEGVPFAVEERSGVITVVDDLS-RYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
G E G+ F ++ +SG++ LS ++ A Q + + T A + V+ VN
Sbjct: 1254 AGNEMGL-FKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGTMESTTKAIITVLRVN 1312
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNM-SSIYGNGTGNVRFLIANQ-QDVTD 728
+ + A S + + + M + NG + + N+ + T
Sbjct: 1313 RHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTG 1372
Query: 729 DIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I E G + + L+R+ R Y + ++A + G + +++ I D N+N P F
Sbjct: 1373 EFKIDEVTGELRAKTQLNRKNRANYDIILVAR-DAGNPPFESLRLLSVSIVDANENRPEF 1431
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
A+ + N G ++K+ + I+A + +F Y L G F VD+ TG +
Sbjct: 1432 PDASNPYKVSINENSGRDVKIGH-IQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDI- 1489
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+ SLDRE+ +Y L ++A S +A+L I + + F S ++R+
Sbjct: 1490 YTNKSLDREETDVYTLYILA------SIKADLHI----SEEERASF------SIKTLNRD 1533
Query: 908 TKLNGTAGFTIIEVKPKNK-FALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
+ A T+++V F + G + N +G I +NA D D G N +I
Sbjct: 1534 NTVAKVA-ITVLDVNDNPPVFEKPIYYAG----VNANAKMGAAITLVNATDADQGKNAKI 1588
Query: 967 RY 968
+
Sbjct: 1589 EF 1590
Score = 93.5 bits (222), Expect = 4e-17
Identities = 129/492 (26%), Positives = 210/492 (42%), Gaps = 60/492 (12%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+TL N P L + N VGTV+ +++A DP+ V Y +
Sbjct: 14 LTLAKGETNLPPVFTQTLNNIILYENVTVGTVVFRLEAYDPE---GSPVTYGAIGADH-- 68
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHAL-FVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
F ++P +G +++ + E + L F+ + +P VV + +T
Sbjct: 69 ----FSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILD 124
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSV-GQIRVNDAFEQNDVSYDLLHGYEEGVPFA--- 621
+ P+F PYE V + +GT++ +I V D + S DL ++ P A
Sbjct: 125 LNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGE-SLDLKCLPQQQSPEACRK 183
Query: 622 ----VEERSGVI----TVVDDLSRYNRPM-YDFEAVALQENANLSIVTNATVHVVDVNDE 672
+ +R I V++D YN+ M Y F+ A T V DV D+
Sbjct: 184 FRLHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQ--TTFEARVKDVQDK 241
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V +G+ S +I E+S + H TG R ++ + + +D +
Sbjct: 242 PPVF-QGSLSTVI---DEDSPINTLVLTVHAR-----DGDTGEPRKIVYDLRTNPNDYFL 292
Query: 733 --AEDGTIFTQKPLDREKRD----VYRMTVIA-EFNKGVISG----AGIYQVTIYIEDEN 781
A+ G + T KPLDRE + + + + A E GV S + + T+ I D N
Sbjct: 293 LDAQTGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVN 352
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
D+PPVF H Y ++EN+ GT + +D + +DAD G N+ F L + +FDV+
Sbjct: 353 DSPPVFNHKEYSVSLLENTLPGTPLALD--MSVSDADVGINSKFALRL-DDVSGVFDVEP 409
Query: 842 N--TGV----VKFIGDSLDREKKIMYK--LSLVARDTG---GLSSEAELIIMIGDENDNK 890
TG ++ +LD E K + +VA +T LSS A + + + D NDNK
Sbjct: 410 KLVTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNK 469
Query: 891 PEFNQIEENSKV 902
P F Q ++ V
Sbjct: 470 PVFEQESYSASV 481
Score = 92.7 bits (220), Expect = 7e-17
Identities = 152/627 (24%), Positives = 251/627 (40%), Gaps = 74/627 (11%)
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAF 601
A R S +VV++ ++ T N D P +P Y V + S ++ DA
Sbjct: 641 ATDDNGRGSASVVSLRISV-TDAN--DSPPVCESPLYRASVDEGAVVFDSPLIVKARDAD 697
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVD----DLSRYNRPMYDFEAVALQENANLS 657
+ +SY + + F ++ +G I + D++ N F A
Sbjct: 698 TMSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAH 757
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNV 716
N TV DVN+ + ++S + V+ENS G ++ ++ T++ + +
Sbjct: 758 CGVNITVR--DVNNHVPNFEQQSYSAV---VEENSEIGTSVERVHATDLDT---GKNAEL 809
Query: 717 RFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
R+ I QQ DD I E G +F + LD ++R+ Y++ + A ++G S G +TI
Sbjct: 810 RYRI--QQGSFDDFGIVETTGEVFVSRKLDFDRRNTYQLQIQAS-DQGTPSLTGTATLTI 866
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIG----TEIKMDNIIKATDADEGTNALFMYTLFG 831
+++ ND P F AT + ++ G T I +D + +A E + +
Sbjct: 867 NVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDK 926
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
EGKE+ D+ K + R K+ L L + + +++ D P
Sbjct: 927 EGKELPHYDQFKEYFK-----ISRNGKVSVNKQL----DRNLFAVMRINVLVTDST--AP 975
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
+++ + I + +N P+ V+Q + E P+GT +
Sbjct: 976 N---VQQGRGLLIIQIIDVNKNP--------PRFNAPWSVEQPQIKLQMVEEQPVGTVLT 1024
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE- 1010
L A D DS + EFN + YF IN+ G + L E
Sbjct: 1025 TLQANDEDSSIG-----EFN--------------ISDNDYFAINQTSGMIYTIARLDYEV 1065
Query: 1011 -SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
E + ++ D G L V V + ++ND+ P F ++ Y FNV E V GKV
Sbjct: 1066 VKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKV 1125
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTG-VLSVNGE-LDRETEDKYILTVVARDN 1125
+A D D G +TY + + + F I TG V+ N LDRE + L+VVA+D
Sbjct: 1126 EAHDGDVGVFGEITYTL-IGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDK 1184
Query: 1126 G-XXXXXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN+P F
Sbjct: 1185 APAAVQKSATATIHINILDVNDNAPVF 1211
Score = 87.8 bits (208), Expect = 2e-15
Identities = 135/494 (27%), Positives = 205/494 (41%), Gaps = 43/494 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+E D + V +T+ D N++ P F + Y ++ N+++GT + +V A D D G+
Sbjct: 747 VEANDGLFTAHCGVNITVRDVNNHVPNFEQQS-YSAVVEENSEIGTSVERVHATDLDTGK 805
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERR 549
N + Y +Q+ S F I TG V V+ + R+ L ++ASDQ PS
Sbjct: 806 NAELRYRIQQGS----FDDFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQ-GTPSLT- 859
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
A +TI V N D P F+ A V ++ G V + D N + +
Sbjct: 860 -GTATLTINVQNS---NDKD-PYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALE 914
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVD 668
G ++ A+++ + D Y + + + +V Q + NL V V V D
Sbjct: 915 FA-GTDDIT--AIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTD 971
Query: 669 VNDERGVLLKGAHSPIIFHVKEN----SAGAAIGQIFHTNMSSIYGNGTGNV-RFLIANQ 723
+G I V +N +A ++ Q + + G V L AN
Sbjct: 972 STAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQP-QIKLQMVEEQPVGTVLTTLQAND 1030
Query: 724 QDVT---------DDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+D + D AI + G I+T LD E + V + GV + V
Sbjct: 1031 EDSSIGEFNISDNDYFAINQTSGMIYTIARLDYEVVKEVKFQVTVS-DTGVPALTATADV 1089
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+ I + NDN P F + Y + ENS GT + ++A D D G YTL GE
Sbjct: 1090 VVDIINLNDNDPKFSQSDYYFNVTENSPRGT---VAGKVEAHDGDVGVFGEITYTLIGEN 1146
Query: 834 KEMFDVDENTGVVKFIGDS-LDREKKIMYKLSLVARDTGGL----SSEAELIIMIGDEND 888
+ F +D TG V S LDRE+ LS+VA+D S+ A + I I D ND
Sbjct: 1147 NKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVND 1206
Query: 889 NKPEFNQIEENSKV 902
N P F + NS V
Sbjct: 1207 NAPVFTRDVYNSTV 1220
Score = 84.6 bits (200), Expect = 2e-14
Identities = 86/347 (24%), Positives = 151/347 (43%), Gaps = 39/347 (11%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
G ++ ++T+ +++ ND P F+ H V P G+ ++ + + P +
Sbjct: 854 GTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQ--LVYTLIALDPDVANHN 911
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDV--HYSIVSGN---------DDGHFAL------- 174
+ T DI A D++ P+ D Y +S N D FA+
Sbjct: 912 ALEFAGT--DDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLV 969
Query: 175 -ESSHKPV-----LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVG 228
+S+ V LL+ +++D + F +I +++ +P+ + L
Sbjct: 970 TDSTAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQAN 1029
Query: 229 ---ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
+++ IS ND F+++ +G ++ LD + ++ QV S P
Sbjct: 1030 DEDSSIGEFNISDND--YFAINQTSGMIYTIARLDYEVVKEVK-----FQVTVSDTGVPA 1082
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
TA A V +++++LNDN P+F Y ++ EN P G +V A D D G GE TY L
Sbjct: 1083 LTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTL 1142
Query: 346 -DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+ FSID +G + V N ++LDRE L + V A++ P+ V
Sbjct: 1143 IGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAV 1189
Score = 80.6 bits (190), Expect = 3e-13
Identities = 82/299 (27%), Positives = 129/299 (43%), Gaps = 30/299 (10%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLTIPLTV---- 134
+T I D+NDN P F +TPY V+E G F + +G SL +
Sbjct: 118 ITFIILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQS 177
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDG--HFALESSHKP----VLLLRKVL 188
P F+ + RD + V ++ N HF +E++ P +V
Sbjct: 178 PEACRKFR-LHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVK 236
Query: 189 DYDAGDKEFQ---LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
D FQ ++ I+ +L +HA D D G + Y+L + N F
Sbjct: 237 DVQDKPPVFQGSLSTVIDEDSPINTLVL---TVHARDGDTGEPRKIVYDLRT-NPNDYFL 292
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN------PLKTAQARVEIELLDL 299
LD+ G L K LD +A + L ++A +L N PL +A A+ + + D+
Sbjct: 293 LDAQTGELRTAKPLDREALED-STGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDV 351
Query: 300 NDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPR 357
ND+ P F Y++S++EN LP L + +D D G N +F +LDD G F ++P+
Sbjct: 352 NDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPK 410
Score = 77.4 bits (182), Expect = 3e-12
Identities = 54/176 (30%), Positives = 90/176 (51%), Gaps = 9/176 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+GV + Y LI G + K FS+D+ G++ + LD E ++ T + Q
Sbjct: 1125 VEAHDGDVGVFGEITYTLI-GENNKYFSIDAYTGNVMVANSSILDREQ-IKELTLSVVAQ 1182
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN--LPNGFSVLQVMATDKDQ 335
K+A A + I +LD+NDN P F D YN ++ EN ++LQV A D+D+
Sbjct: 1183 DKAPAAVQKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDE 1242
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
G G+ Y + + G F +D +SG + Q++ + H + + + A++T S
Sbjct: 1243 GLYGDVRYIITAGNEMGLFKLDAQSG-IVYPAQSLSGK--HGAYELTISARDTQGS 1295
Score = 72.1 bits (169), Expect = 1e-10
Identities = 116/472 (24%), Positives = 187/472 (39%), Gaps = 57/472 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN P GT K+ A D D G+ G+I Y E +YF I+
Sbjct: 1110 FNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGEN--------------NKYFSIDAY 1155
Query: 998 HGHVIVARS--LPPES--EFRLNISALDGG----NLNDNISVRVFVKDVNDHFPVFKKTW 1049
G+V+VA S L E E L++ A D + ++ + + DVND+ PVF +
Sbjct: 1156 TGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTRDV 1215
Query: 1050 YNFNVEE--AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
YN V E A L +V A D D G ++ Y I + F++ +G++
Sbjct: 1216 YNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSGIVYPAQS 1275
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
L + Y LT+ ARD VN + P+F L +
Sbjct: 1276 LSGK-HGAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEF-VIPALSNATIEIPGD 1333
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT---DF-IGNGNG-LILYSLPQRK 1222
+ ++ ++ + EEN + + N+ +F I G L + RK
Sbjct: 1334 IVQPDY-LLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLNRK 1392
Query: 1223 NQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVF--ISRYYELEIEENVN 1271
N+ N G P S +L V++ D + ++P F S Y++ I EN
Sbjct: 1393 NRANYDIILVARDAGNPPFESLRLLSVSIVDANE-----NRPEFPDASNPYKVSINENSG 1447
Query: 1272 APVELVSLNLTEHYE-NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
V++ + + N + YY+L N+ F +D G +Y +S DRE D Y
Sbjct: 1448 RDVKIGHIQAASRSKHNRDIFYYMLLGNEDG---AFYVDKLTGDIYTNKSLDREETDVYT 1504
Query: 1331 VIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD--VKVVVRIKDVNDNSPKF 1380
+ + A +L A ++ + + + KV + + DVNDN P F
Sbjct: 1505 LYILA---SIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDVNDNPPVF 1553
Score = 71.7 bits (168), Expect = 1e-10
Identities = 52/185 (28%), Positives = 90/185 (48%), Gaps = 9/185 (4%)
Query: 212 ILFPEPIHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQA 269
++F P+ +D + + Y I G+++ +F +D G + + LD NL +
Sbjct: 683 VVFDSPLIVKARDADTMSRISYR-IRGSEQVESIFDIDRETGQIIIRPNATLDVT-NLNS 740
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ + V+A N+ L TA V I + D+N+++P FE Y+ + EN G SV +V
Sbjct: 741 DQLIFAVEA---NDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVH 797
Query: 330 ATDKDQGENGEFTYQLDDPK-GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
ATD D G+N E Y++ F I +G + V + DR L+++ + + P
Sbjct: 798 ATDLDTGKNAELRYRIQQGSFDDFGIVETTGEVFVSRKLDFDRRNTYQLQIQA-SDQGTP 856
Query: 389 SVVGT 393
S+ GT
Sbjct: 857 SLTGT 861
Score = 62.1 bits (144), Expect = 1e-07
Identities = 68/271 (25%), Positives = 113/271 (41%), Gaps = 28/271 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
++ +S+ + + D ND+ P+ Y +VDE + I I + RG
Sbjct: 650 ASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKARDADTMSRISYRI-RG 708
Query: 138 LTIFKDIRAFDRD------KPNTP------NSDVHYSIVSGNDDGHFALESSHKPV-LLL 184
+ I DR+ +PN NSD V ND L ++H V + +
Sbjct: 709 SEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEAND----GLFTAHCGVNITV 764
Query: 185 RKVLDYDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
R V ++ +++ ++ I + E +HA D D G A LRY + G+
Sbjct: 765 RDVNNHVPNFEQQSYSAVVEENSEIGTSV---ERVHATDLDTGKNAELRYRIQQGSFDD- 820
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F + G +F+ ++LD D + NT+ LQ+QAS P T A + I + + ND
Sbjct: 821 FGIVETTGEVFVSRKLDFD-----RRNTYQLQIQASDQGTPSLTGTATLTINVQNSNDKD 875
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
P F + + + P G V ++A D D
Sbjct: 876 PYFVPATQHAEVRADAPPGQLVYTLIALDPD 906
Score = 59.3 bits (137), Expect = 8e-07
Identities = 79/319 (24%), Positives = 133/319 (41%), Gaps = 32/319 (10%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVP 135
Q SA ++ + I DVNDN P+F Y+ TV E A + + I + V
Sbjct: 1190 QKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVR 1249
Query: 136 RGLTIFKDIRAFDRDK------PNTPNSDVH--YSI-VSGND-DGHFALESSHKPVLLLR 185
+T ++ F D P S H Y + +S D G +ES+ K ++
Sbjct: 1250 YIITAGNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGTMESTTKAII--- 1306
Query: 186 KVLDYDAGDKEFQLVIMASGK-RIHKEILFPE----PIHAIDQDLGVGATLRYELISGND 240
VL + EF + +++ I +I+ P+ + A+D D + Y L N
Sbjct: 1307 TVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNR 1366
Query: 241 RKL----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
+ F +D V G L + +L+ +AN ++ V N P ++ + + + +
Sbjct: 1367 NEQQTGEFKIDEVTGELRAKTQLN----RKNRANYDIILVARDAGNPPFESLRL-LSVSI 1421
Query: 297 LDLNDNLPEF--EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFS 353
+D N+N PEF + Y +SI EN + + A + + F Y L + GAF
Sbjct: 1422 VDANENRPEFPDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFY 1481
Query: 354 IDPRSGWLTVRNQTVLDRE 372
+D +G + LDRE
Sbjct: 1482 VDKLTG--DIYTNKSLDRE 1498
Score = 57.6 bits (133), Expect = 2e-06
Identities = 108/470 (22%), Positives = 188/470 (40%), Gaps = 66/470 (14%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI-GKVKAVDPDLGQNGMVLYDLQR 501
V + +LD NDN P F + YE + +A VGT I K+ D D+ + L L +
Sbjct: 116 VPITFIILDLNDNPPEF-QNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQ 174
Query: 502 TSNLTITSPFKINPNTGTVSVAESPIL------EGRHALF---VEASDQPANPSERRYSL 552
+ F+++ ++ E+ ++ + ++ +EA+D P + ++ +
Sbjct: 175 QQSPEACRKFRLHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDGP-HKTQTTFEA 233
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDL 610
V ++ +KP P F G+ + + I T V + R D E + YDL
Sbjct: 234 RVKDVQ-------DKP--PVFQGS-LSTVIDEDSPINTLVLTVHARDGDTGEPRKIVYDL 283
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRY---NRPMYDFEAVALQENAN--------LSIV 659
+ F ++ ++G + L R + + +E N S
Sbjct: 284 RTNPNDY--FLLDAQTGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSAT 341
Query: 660 TNATVHVVDVNDERGVLLKGAHS-----------PIIFHVKENSAGAAIGQIFHTNMSSI 708
ATV + DVND V +S P+ + + A I F + +
Sbjct: 342 AKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDV 401
Query: 709 YGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
G + L+ V +A +GT+ + P R+ + + V+AE +
Sbjct: 402 SGVFDVEPK-LVTGYSQVNIRVA---NGTLDYENPNQRK----FIVLVVAEETDTNPRLS 453
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFM 826
+T+ + D NDN PVFE +Y + E + G I I A D D G+ ++
Sbjct: 454 STATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIA---TITARDVDSGSYGDSGIR 510
Query: 827 YTLFGEGKEMFDVDENTGVVKFI-----GDSLDREKKIMYKLSLVARDTG 871
Y+L G G E+F V+E TGV+ G+S RE++ + + V D G
Sbjct: 511 YSLSGTGAELFHVNEQTGVISLANCHDNGESNRRERRDLNEDEHVEEDDG 560
Score = 53.2 bits (122), Expect = 5e-05
Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEH--------NLQANTFVLQVQASQLNNP 284
Y ++ GN+ F +D + G ++ K LD + +++A+ + + + + +
Sbjct: 1469 YYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFS-- 1526
Query: 285 LKTAQ-----ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+KT A+V I +LD+NDN P FE Y + N G ++ V ATD DQG+N
Sbjct: 1527 IKTLNRDNTVAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNA 1586
Query: 340 EFTYQL 345
+ + +
Sbjct: 1587 KIEFMI 1592
Score = 52.8 bits (121), Expect = 7e-05
Identities = 87/373 (23%), Positives = 151/373 (40%), Gaps = 51/373 (13%)
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIY--IEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
Y ++ F G Q T ++D D PPVF+ + I E+S I T +
Sbjct: 208 YNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDKPPVFQ-GSLSTVIDEDSPINTLVLT- 265
Query: 810 NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
+ A D D G +Y L + F +D TG ++ LDRE D
Sbjct: 266 --VHARDGDTGEPRKIVYDLRTNPNDYFLLDAQTGELR-TAKPLDRE---------ALED 313
Query: 870 TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFAL 929
+ G+ S L+I + + P + + T A TI +V
Sbjct: 314 STGIIS---LVIRARELVNGVPSDDPL-----------TSATAKATVTIRDVNDSPPVFN 359
Query: 930 DVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ--IRYEFNSEVYIPPSKLSADALE 987
+ + L+ +P + ++ D D G+N + +R + S V+ KL
Sbjct: 360 HKEY--SVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKL------ 411
Query: 988 VKRYFVINERHGHVIVARSLPPESEFRLNISALD---GGNLNDNISVRVFVKDVNDHFPV 1044
V Y +N R + + P + +F + + A + L+ ++ V V D ND+ PV
Sbjct: 412 VTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPV 471
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ--NANLTYFIQPSDTDLPFEISPLTGVL 1102
F++ Y+ +V EA + + + A D D G ++ + Y + + +L F ++ TGV+
Sbjct: 472 FEQESYSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGAEL-FHVNEQTGVI 530
Query: 1103 SV-----NGELDR 1110
S+ NGE +R
Sbjct: 531 SLANCHDNGESNR 543
Score = 50.8 bits (116), Expect = 3e-04
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+LD NDN PVF +Y + +NAK+G I V A D D G+N + + + SN
Sbjct: 1539 VAITVLDVNDNPPVF-EKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIV-ASN 1596
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
L +K T S+ SP + + A+ A ++ R+ L +V E+
Sbjct: 1597 L-----YKFGATKSTGSIVPSPFAISQDGR-ISANTIMAEYNQDRFELEIVAREL 1645
Score = 49.6 bits (113), Expect = 6e-04
Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 3/108 (2%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
LD E+ Q VL V NP ++ A + + +LD NDN P FE + Y+ S+ E
Sbjct: 427 LDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAAL 486
Query: 321 NGFSVLQVMATDKDQGENGE--FTYQLDDPKG-AFSIDPRSGWLTVRN 365
G + + A D D G G+ Y L F ++ ++G +++ N
Sbjct: 487 PGQYIATITARDVDSGSYGDSGIRYSLSGTGAELFHVNEQTGVISLAN 534
Score = 49.6 bits (113), Expect = 6e-04
Identities = 45/170 (26%), Positives = 75/170 (44%), Gaps = 12/170 (7%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
Q LD E Y ++ A + G S A + + I + D ND+PPV E Y + E +
Sbjct: 624 QTCLDYESETTYFLSYKATDDNGRGS-ASVVSLRISVTDANDSPPVCESPLYRASVDEGA 682
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG-VVKFIGDSLDREKKI 859
+ I+KA DAD + + + + +FD+D TG ++ +LD
Sbjct: 683 VV---FDSPLIVKARDADTMSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLN 739
Query: 860 MYKLSLVARDTGGL-SSEAELIIMIGDENDNKPEFNQ------IEENSKV 902
+L GL ++ + I + D N++ P F Q +EENS++
Sbjct: 740 SDQLIFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEI 789
Score = 48.8 bits (111), Expect = 0.001
Identities = 59/226 (26%), Positives = 93/226 (41%), Gaps = 18/226 (7%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEF--NSEVYIPPSKLSADALEVKRYFVIN- 995
+I E+ PI T ++ ++A D D+G +I Y+ N Y L A E++ ++
Sbjct: 252 VIDEDSPINTLVLTVHARDGDTGEPRKIVYDLRTNPNDYF---LLDAQTGELRTAKPLDR 308
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
E SL + +N D + V ++DVND PVF Y+ ++
Sbjct: 309 EALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLL 368
Query: 1056 EAQYTRRVLG-KVDATDADFGQNANLTYFIQPSDTDLPFEISP--LTGVLSVN-----GE 1107
E L + +DAD G N+ + ++ D F++ P +TG VN G
Sbjct: 369 ENTLPGTPLALDMSVSDADVGINSK--FALRLDDVSGVFDVEPKLVTGYSQVNIRVANGT 426
Query: 1108 LDRETED--KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD E + K+I+ VVA + D NDN P F
Sbjct: 427 LDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVF 472
Score = 45.2 bits (102), Expect = 0.014
Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 14/112 (12%)
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
N V + V DVND+ PVF+K Y V + V+ATDAD G+NA + + I
Sbjct: 1534 NTVAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIV 1593
Query: 1086 PSD-------------TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
S+ PF IS G +S N + +D++ L +VAR+
Sbjct: 1594 ASNLYKFGATKSTGSIVPSPFAISQ-DGRISANTIMAEYNQDRFELEIVARE 1644
Score = 44.8 bits (101), Expect = 0.018
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG--MV 495
+L S + V++LDANDN PVF + Y S+ A G I + A D D G G +
Sbjct: 451 RLSSTATITVSVLDANDNKPVFEQES-YSASVSEAALPGQYIATITARDVDSGSYGDSGI 509
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVA 523
Y L T F +N TG +S+A
Sbjct: 510 RYSLSGTG----AELFHVNEQTGVISLA 533
Score = 41.9 bits (94), Expect = 0.13
Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V Q + P KT Q E + D+ D P F+ + I E+ P VL V A D
Sbjct: 213 VYHFQIEATDGPHKT-QTTFEARVKDVQDKPPVFQGSLSTV-IDEDSPINTLVLTVHARD 270
Query: 333 KDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREA 373
D GE + Y L +P F +D ++G L R LDREA
Sbjct: 271 GDTGEPRKIVYDLRTNPNDYFLLDAQTGEL--RTAKPLDREA 310
Score = 39.1 bits (87), Expect = 0.92
Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVL-QVQASQLNNPLKTAQARVEIELLDLNDN 302
FS+D V+G++ L K LD + + L+ + +V + + + +LDLNDN
Sbjct: 69 FSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDN 128
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
PEF+ Y + E+ G ++ + T KD+ GE
Sbjct: 129 PPEFQNTPYEADVNEDAAVGTTIFDKI-TVKDRDIVGE 165
Score = 38.7 bits (86), Expect = 1.2
Identities = 46/154 (29%), Positives = 64/154 (41%), Gaps = 20/154 (12%)
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
E + PPVF + EN +GT + ++A D EG+ T G + F V
Sbjct: 20 ETNLPPVFTQTLNNIILYENVTVGTVVFR---LEAYDP-EGSPV----TYGAIGADHFSV 71
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE--------LIIMIGDENDNKP 891
D +G + I LDRE+K K + RD E+E + +I D NDN P
Sbjct: 72 DPVSGNITLI-KPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPP 130
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
EF + V E GT F I VK ++
Sbjct: 131 EFQNTPYEADV---NEDAAVGTTIFDKITVKDRD 161
Score = 36.3 bits (80), Expect = 6.5
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 11/77 (14%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
F +DP +G + L++ DRE KDT + +V + + P E + + +V
Sbjct: 69 FSVDPVSGNITLIKPLDREEKDTLKFLV---------SIRDRVDPEGESERDNVV--EVP 117
Query: 1366 VVVRIKDVNDNSPKFTN 1382
+ I D+NDN P+F N
Sbjct: 118 ITFIILDLNDNPPEFQN 134
>UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whole
genome shotgun sequence; n=2; cellular organisms|Rep:
Chromosome undetermined SCAF14743, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 2087
Score = 113 bits (271), Expect = 5e-23
Identities = 171/672 (25%), Positives = 278/672 (41%), Gaps = 73/672 (10%)
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
F L+V+ + + + V + + D+NDN+P F Y ++ E G SV QV A
Sbjct: 569 FTLRVRVQNVASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAA 628
Query: 332 DKDQGENGEFTYQ-LDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMK-VYA--- 383
D D G +G Y L D G F ID SG + R DRE +S ++ +Y
Sbjct: 629 DLDSGPHGTVRYLILRDDSGDWRFFDIDSLSGAIVSRAS--FDREQKASYLLESLYEVSV 686
Query: 384 ---KETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGT--KTENIEYYDE- 437
KE ++ A+ + + + A + +VGT ++Y E
Sbjct: 687 EEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGTIFVARPLDYEAER 746
Query: 438 --QLMSFVN---------VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
QL + V V +L+ ND PVF S + + +++ +I +V A D
Sbjct: 747 RYQLRLVASDGKWENETLVVVEVLNRNDEAPVFSQSQYHAAVTEELSQLPVLILQVSATD 806
Query: 487 PDL-GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPA 543
PD G + Y L F ++ +G++ E R V A+D+
Sbjct: 807 PDQEADQGALRYSLHGQG---AGGEFTVDQRSGSIYAHRRLDREERPTWRFLVLATDE-- 861
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIP-DFMGAPYEF--WVGSNVGIGTSVGQIRVNDA 600
A V +EV R N P P + A F V N TSV ++R D
Sbjct: 862 -GGAGLTGFADVLLEV-RDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEMRATDL 919
Query: 601 FEQN-----DVSYDLLHGYEEGVP---FAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQ 651
+ N ++Y ++ + F++ +G I TV+ L R + V +
Sbjct: 920 DDPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERH-LVVVEAR 978
Query: 652 ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN 711
+ L+ AT+ V DVND V + +S + ++ G+ + + + M G
Sbjct: 979 DGEGLAGTGTATIIVSDVNDHAPVFTQRLYSAQV--TEDLEVGSQV--LVVSAMDQDEGQ 1034
Query: 712 GTGNVRFLIANQQD---VTDDIAIAEDGTIFTQKPLDREK--RDVYRMTVIAEFNKGVIS 766
++ +D + + G I QK +D EK V+ +TV AE + S
Sbjct: 1035 NAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKPQERVFNLTVKAE-DSDFFS 1093
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ + +ED ND+ PVF YE + E++ GT + + A+DAD G N
Sbjct: 1094 ---LSSCLVRVEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQ---VTASDADSGQNGRL 1147
Query: 826 MYTLFGEGKEM--FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELII 881
Y++ + + F VD++ V+ + SLDREK +++ L+A D G L+ A LI+
Sbjct: 1148 SYSISRQSDPLGQFLVDQSGWVL--LAGSLDREKTSQHRILLLATDAGTPALTGTAVLIV 1205
Query: 882 MIGDENDNKPEF 893
+ D NDN PEF
Sbjct: 1206 TVLDVNDNGPEF 1217
Score = 110 bits (265), Expect = 2e-22
Identities = 123/460 (26%), Positives = 214/460 (46%), Gaps = 47/460 (10%)
Query: 459 FVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTG 518
++ +LYE S++ + +VG VI V A D D G N + Y + +++ F + P G
Sbjct: 676 YLLESLYEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSM---GAFDVEPEVG 732
Query: 519 TVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMG 575
T+ VA P+ E R+ L + ASD + + +V +EV + P F
Sbjct: 733 TIFVAR-PLDYEAERRYQLRLVASDG------KWENETLVVVEVLN----RNDEAPVFSQ 781
Query: 576 APYEFWVGSNVG-IGTSVGQIRVNDAFEQND---VSYDLLHGYEEGVPFAVEERSGVITV 631
+ Y V + + + Q+ D ++ D + Y L HG G F V++RSG I
Sbjct: 782 SQYHAAVTEELSQLPVLILQVSATDPDQEADQGALRYSL-HGQGAGGEFTVDQRSGSIYA 840
Query: 632 VDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVL---LKGAHSPIIFH 687
L R RP + F +A E A L+ + + V DVND A +
Sbjct: 841 HRRLDREERPTWRFLVLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGR 900
Query: 688 VKENS-AGAAIGQIFHTNMS--SIYGNG--TGNVRFLIANQQDVTDDIAIAEDGTIFTQ- 741
V ENS A ++ ++ T++ ++ N T ++ + NQ ++ GTI+T
Sbjct: 901 VAENSPADTSVMEMRATDLDDPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVL 960
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
+ LDRE+ + + + V A +G+ AG TI + D ND+ PVF Y + E+ +
Sbjct: 961 RSLDREEAERHLVVVEARDGEGL---AGTGTATIIVSDVNDHAPVFTQRLYSAQVTEDLE 1017
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMF---DVDENTGVVKFIGDSLDRE 856
+G+++ ++ A D DEG NA +++ G E ++ F D GV++ + +D E
Sbjct: 1018 VGSQVL---VVSAMDQDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIR-LQKKVDFE 1073
Query: 857 K--KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
K + ++ L++ A D+ S + ++ + D ND+ P F+
Sbjct: 1074 KPQERVFNLTVKAEDS-DFFSLSSCLVRVEDANDHAPVFS 1112
Score = 94.3 bits (224), Expect = 2e-17
Identities = 96/327 (29%), Positives = 144/327 (44%), Gaps = 45/327 (13%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTV 134
++++ +V V + DVNDNVP FL + Y TV E TG A + GP T+ +
Sbjct: 583 LASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLI 642
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAG- 193
R + D R FD D +SG + + K LL + +
Sbjct: 643 LRDDS--GDWRFFDIDS------------LSGAIVSRASFDREQKASYLLESLYEVSVEE 688
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
DKE VI+ + A D+D G A LRY++ +GN F ++ G++
Sbjct: 689 DKEVGFVIIT--------------VTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGTI 734
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
F+ + LD +AE Q L++ AS +T V +E+L+ ND P F Y+
Sbjct: 735 FVARPLDYEAERRYQ-----LRLVASDGKWENETL---VVVEVLNRNDEAPVFSQSQYHA 786
Query: 314 SIVENLPN-GFSVLQVMATDKDQ-GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVL 369
++ E L +LQV ATD DQ + G Y L G F++D RSG + + L
Sbjct: 787 AVTEELSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGSIYAHRR--L 844
Query: 370 DREAHSSLRMKVYAKETNPSVVGTFAD 396
DRE + R V A + + + FAD
Sbjct: 845 DREERPTWRFLVLATDEGGAGLTGFAD 871
Score = 84.6 bits (200), Expect = 2e-14
Identities = 82/331 (24%), Positives = 133/331 (40%), Gaps = 20/331 (6%)
Query: 578 YEFWVGSNVGIGTSVGQIRVNDAFEQNDVS--YDLLHGYEEGVPFAVEERSGVITVVDDL 635
YE V + +G + + ND E + Y + G G F VE G I V L
Sbjct: 682 YEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGA-FDVEPEVGTIFVARPL 740
Query: 636 SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGA 695
Y VA + T V V++ NDE V + + + + +
Sbjct: 741 DYEAERRYQLRLVA--SDGKWENETLVVVEVLNRNDEAPVFSQSQYHAAVTE-ELSQLPV 797
Query: 696 AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMT 755
I Q+ T+ G +R+ + Q + G+I+ + LDRE+R +R
Sbjct: 798 LILQVSATDPDQEADQGA--LRYSLHGQGAGGEFTVDQRSGSIYAHRRLDREERPTWRFL 855
Query: 756 VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE------HATYEGFIMENSKIGTEIKMD 809
V+A ++G G V + + D NDN P F + G + ENS T +
Sbjct: 856 VLAT-DEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEM 914
Query: 810 NIIKATDADEGTNALFMYTLFGEGKE-----MFDVDENTGVVKFIGDSLDREKKIMYKLS 864
D + G NA+ Y++ + +F ++ TG + + SLDRE+ + +
Sbjct: 915 RATDLDDPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVV 974
Query: 865 LVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+ ARD GL+ I++ D ND+ P F Q
Sbjct: 975 VEARDGEGLAGTGTATIIVSDVNDHAPVFTQ 1005
Score = 81.4 bits (192), Expect = 2e-13
Identities = 64/186 (34%), Positives = 96/186 (51%), Gaps = 20/186 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGN-DRKLF-SLDSVN--GSLFLEKELDLDAEHNLQANTFV 273
+ A+DQD G A + + ++ G+ DRK F D VN G + L+K++D + Q F
Sbjct: 1025 VSAMDQDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKP---QERVFN 1081
Query: 274 LQVQASQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIV-ENLPNGFSVLQVMAT 331
L V+A + L + RVE D ND+ P F FY + + E+ G V QV A+
Sbjct: 1082 LTVKAEDSDFFSLSSCLVRVE----DANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTAS 1137
Query: 332 DKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-N 387
D D G+NG +Y + DP G F +D +SGW+ + LDRE S R+ + A +
Sbjct: 1138 DADSGQNGRLSYSISRQSDPLGQFLVD-QSGWVLLAGS--LDREKTSQHRILLLATDAGT 1194
Query: 388 PSVVGT 393
P++ GT
Sbjct: 1195 PALTGT 1200
Score = 75.8 bits (178), Expect = 9e-12
Identities = 67/245 (27%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L GT TII V N A Q + E++ +G+ ++ ++A+D D G N + +
Sbjct: 983 LAGTGTATII-VSDVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQNAAVTFS 1041
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI 1029
L D + + + ++ V P E F L + A D + +
Sbjct: 1042 IVGGDEDRKFFLETDRVNRRGVIRLQKK-----VDFEKPQERVFNLTVKAEDSDFFSLS- 1095
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFN-VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
S V V+D NDH PVF +Y + E ++ +V A+DAD GQN L+Y I
Sbjct: 1096 SCLVRVEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRLSYSISRQS 1155
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
L + +G + + G LDRE ++ + ++A D G DVNDN
Sbjct: 1156 DPLGQFLVDQSGWVLLAGSLDREKTSQHRILLLATDAG-TPALTGTAVLIVTVLDVNDNG 1214
Query: 1149 PKFYA 1153
P+F A
Sbjct: 1215 PEFEA 1219
Score = 74.5 bits (175), Expect = 2e-11
Identities = 96/345 (27%), Positives = 153/345 (44%), Gaps = 49/345 (14%)
Query: 940 IPENIPIGTTIIKLNALDLDS---GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+ EN P T+++++ A DLD G N + Y V ++++ + F IN
Sbjct: 901 VAENSPADTSVMEMRATDLDDPNVGANAILTYSIIQNVR---NQINLNL------FSING 951
Query: 997 RHGHVI-VARSLPPESEFR--LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + V RSL E R + + A DG L + + V DVNDH PVF + Y+
Sbjct: 952 ATGTIYTVLRSLDREEAERHLVVVEARDGEGLAGTGTATIIVSDVNDHAPVFTQRLYSAQ 1011
Query: 1054 V-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP----LTGVLSVNGEL 1108
V E+ + +VL V A D D GQNA +T+ I D D F + GV+ + ++
Sbjct: 1012 VTEDLEVGSQVL-VVSAMDQDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKV 1070
Query: 1109 DRE--TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
D E E + LTV A D+ D ND++P F + EA
Sbjct: 1071 DFEKPQERVFNLTVKAEDS----DFFSLSSCLVRVEDANDHAPVFSP-------QFYEAA 1119
Query: 1167 ELSNHNFESVMMIPVYKATIE--ENAPIGTTVAKVFANDTDFIGNGNGLILY--SLPQRK 1222
LS ++ V + + +N + ++++ F+ + +G +L SL + K
Sbjct: 1120 ALSEDTAAGTIVTQVTASDADSGQNGRLSYSISRQSDPLGQFLVDQSGWVLLAGSLDREK 1179
Query: 1223 NQQ--------NLGLPSLSSTAILMVTVADVPD---EVEMSDKPV 1256
Q + G P+L+ TA+L+VTV DV D E E + +P+
Sbjct: 1180 TSQHRILLLATDAGTPALTGTAVLIVTVLDVNDNGPEFEAAYRPM 1224
Score = 73.7 bits (173), Expect = 3e-11
Identities = 97/372 (26%), Positives = 157/372 (42%), Gaps = 37/372 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVF-VPS----NLYEFSMKSNAKVGTVIGKVKAV---DPDLG 490
L F +V + + D NDN P F P+ + + N+ T + +++A DP++G
Sbjct: 866 LTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEMRATDLDDPNVG 925
Query: 491 QNGMVLYD-LQRTSNLTITSPFKINPNTGTV-SVAESPILE--GRHALFVEASDQPANPS 546
N ++ Y +Q N + F IN TGT+ +V S E RH + VEA D
Sbjct: 926 ANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVVVEARD-----G 980
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN- 604
E TI V+ P F Y V ++ +G+ V + D E QN
Sbjct: 981 EGLAGTGTATIIVS----DVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQNA 1036
Query: 605 DVSYDLLHGYEEGVPFAVEE---RSGVITVVDDLSRYNRPMYD-FEAVALQENANLSIVT 660
V++ ++ G E+ F + R GVI + + + +P F E+++ ++
Sbjct: 1037 AVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVD-FEKPQERVFNLTVKAEDSDFFSLS 1095
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFL 719
+ V V D ND V SP + S A G I +S +G G + +
Sbjct: 1096 SCLVRVEDANDHAPVF-----SPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRLSYS 1150
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIE 778
I+ Q D + + G + LDREK +R+ ++A + ++G + VT+
Sbjct: 1151 ISRQSDPLGQFLVDQSGWVLLAGSLDREKTSQHRILLLATDAGTPALTGTAVLIVTVL-- 1208
Query: 779 DENDNPPVFEHA 790
D NDN P FE A
Sbjct: 1209 DVNDNGPEFEAA 1220
Score = 69.7 bits (163), Expect = 6e-10
Identities = 93/360 (25%), Positives = 152/360 (42%), Gaps = 43/360 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +G II + A D D G N ++RY+ + + + A F + G
Sbjct: 686 VEEDKEVGFVIITVTANDEDEGANAKLRYQIAAG-----NSMGA--------FDVEPEVG 732
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EE 1056
+ VAR L E+E ++L + A DG N+ + V V V + ND PVF ++ Y+ V EE
Sbjct: 733 TIFVARPLDYEAERRYQLRLVASDGKWENETLVV-VEVLNRNDEAPVFSQSQYHAAVTEE 791
Query: 1057 AQYTRRVLGKVDATDADF-GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
++ +V ATD D L Y + F + +G + + LDRE
Sbjct: 792 LSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGSIYAHRRLDREERPT 851
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ V+A D G DVNDN+P F+ L +A+
Sbjct: 852 WRFLVLATDEG-GAGLTGFADVLLEVRDVNDNAP-FFPCPAL------QAE--------- 894
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG-NGLILYSLPQR-KNQQNLGLPSLS 1233
+ + EN+P T+V ++ A D D G N ++ YS+ Q +NQ NL L S++
Sbjct: 895 ----GCFVGRVAENSPADTSVMEMRATDLDDPNVGANAILTYSIIQNVRNQINLNLFSIN 950
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYY 1293
+ TV D E +++ + + + E +VS ++ +H F R Y
Sbjct: 951 GATGTIYTVLRSLDR-EEAERHLVVVEARDGEGLAGTGTATIIVS-DVNDHAPVFTQRLY 1008
Score = 59.3 bits (137), Expect = 8e-07
Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 49/350 (14%)
Query: 1005 RSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
RS S I A DGGN + ++ + VF+ +V++ P + + Y V E +
Sbjct: 451 RSSAQTSRIVRQIVASDGGNRSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKI 510
Query: 1065 GKVDATDADFGQNANLTYFI---QPSDTDLP--FEISPL----TGVLSVNGELDRETEDK 1115
+ AT + G + +TY + Q +T++P F + P + + V LD ET
Sbjct: 511 VTIKAT-SPLG-DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGF 568
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
+ L V + N DVNDN P F LS+
Sbjct: 569 FTLRVRVQ-NVASVPLASFTTVYVNVTDVNDNVPFF----------------LSS----- 606
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSST 1235
Y+AT+ E A GT+VA+V A D D +G + Y L R + + + S
Sbjct: 607 -----TYEATVPEGAQTGTSVAQVSAADLD--SGPHGTVRY-LILRDDSGDWRFFDIDSL 658
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYY 1293
+ +V+ A E + S + YE+ +EE+ ++++ + E N K+RY
Sbjct: 659 SGAIVSRASFDREQKAS---YLLESLYEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQ 715
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
I N F ++P GT+++ R D E + Y++ + A K+ E
Sbjct: 716 IAAGNSMG---AFDVEPEVGTIFVARPLDYEAERRYQLRLVASDGKWENE 762
Score = 54.8 bits (126), Expect = 2e-05
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
F+ +SGA + + + D + YE + E+ ++G I + A D DE
Sbjct: 653 FDIDSLSGAIVSRASF---DREQKASYLLESLYEVSVEEDKEVGFVIIT---VTANDEDE 706
Query: 820 GTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
G NA Y + G FDV+ G + F+ LD E + Y+L LVA D G +E
Sbjct: 707 GANAKLRYQIAAGNSMGAFDVEPEVGTI-FVARPLDYEAERRYQLRLVASD-GKWENETL 764
Query: 879 LIIMIGDENDNKPEFNQIEENSKV 902
+++ + + ND P F+Q + ++ V
Sbjct: 765 VVVEVLNRNDEAPVFSQSQYHAAV 788
Score = 53.2 bits (122), Expect = 5e-05
Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 17/177 (9%)
Query: 716 VRFLIA-NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
VRF + N+ D + I +AE+ LD E + + V + N + A V
Sbjct: 540 VRFYVKPNRADGSASILVAEN--------LDFETTGFFTLRVRVQ-NVASVPLASFTTVY 590
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ + D NDN P F +TYE + E ++ GT + + A D D G + Y + +
Sbjct: 591 VNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQ---VSAADLDSGPHGTVRYLILRDDS 647
Query: 835 ---EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEND 888
FD+D +G + S DRE+K Y L + + E +I+ ND
Sbjct: 648 GDWRFFDIDSLSGAI-VSRASFDREQKASYLLESLYEVSVEEDKEVGFVIITVTAND 703
Score = 51.2 bits (117), Expect = 2e-04
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 222 DQDLGVGATLRYELISGNDRK----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
D ++G A L Y +I + LFS++ G+++ LD E +A ++ V+
Sbjct: 921 DPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLR-SLDRE---EAERHLVVVE 976
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A T A + + D+ND+ P F Y+ + E+L G VL V A D+D+G+
Sbjct: 977 ARDGEGLAGTGTATIIVS--DVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQ 1034
Query: 338 NGEFTYQL 345
N T+ +
Sbjct: 1035 NAAVTFSI 1042
Score = 50.8 bits (116), Expect = 3e-04
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 8/141 (5%)
Query: 986 LEVKRYFVINERHGH--VIVARSLPPESE----FRLNISALDGGNLNDNISVRVFVKDVN 1039
+ V+ Y N G ++VA +L E+ R+ + + L +V V V DVN
Sbjct: 538 MPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNVASVPLASFTTVYVNVTDVN 597
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD--LPFEISP 1097
D+ P F + Y V E T + +V A D D G + + Y I D+ F+I
Sbjct: 598 DNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLILRDDSGDWRFFDIDS 657
Query: 1098 LTGVLSVNGELDRETEDKYIL 1118
L+G + DRE + Y+L
Sbjct: 658 LSGAIVSRASFDREQKASYLL 678
Score = 45.6 bits (103), Expect = 0.011
Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 12/127 (9%)
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG--KEMFDVDEN 842
P + + ++EN GT + ++A DAD G N Y + F +D +
Sbjct: 130 PQCHNYSQRAVVLENQPPGTGVLR---VQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPD 186
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENS 900
G + S DRE++ + LS+ A D L ++ +++ D+NDN+P+F ENS
Sbjct: 187 AGYITTTV-SFDRERQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKF----ENS 241
Query: 901 KVRIHRE 907
+ + +E
Sbjct: 242 RYQSTQE 248
Score = 44.8 bits (101), Expect = 0.018
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 714 GNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ 772
G V++ I ++ V+ I D G I T DRE++ + ++V A ++ GI Q
Sbjct: 165 GQVKYGIMHRDGVSSGFHIDPDAGYITTTVSFDRERQREFTLSVTAT-DQADEPLIGICQ 223
Query: 773 VTIYIEDENDNPPVFEHATYE 793
+T+ + D+NDN P FE++ Y+
Sbjct: 224 ITVLVADQNDNEPKFENSRYQ 244
Score = 44.4 bits (100), Expect = 0.024
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDR 371
++EN P G VL+V A D D G NG+ Y + D F IDP +G++T DR
Sbjct: 141 VLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPDAGYIT--TTVSFDR 198
Query: 372 EAHSSLRMKVYAKE 385
E + V A +
Sbjct: 199 ERQREFTLSVTATD 212
Score = 44.0 bits (99), Expect = 0.032
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 2/87 (2%)
Query: 1066 KVDATDADFGQNANLTYFIQPSD-TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+V A DAD G N + Y I D F I P G ++ DRE + ++ L+V A D
Sbjct: 153 RVQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPDAGYITTTVSFDRERQREFTLSVTATD 212
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D NDN PKF
Sbjct: 213 Q-ADEPLIGICQITVLVADQNDNEPKF 238
Score = 44.0 bits (99), Expect = 0.032
Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 15/133 (11%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
DQ+ GA LRY L F++D +GS++ + LD + + T+ V A+
Sbjct: 808 DQEADQGA-LRYSLHGQGAGGEFTVDQRSGSIYAHRRLDRE-----ERPTWRFLVLATDE 861
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS------IVENLPNGFSVLQVMATDKDQ 335
T A V +E+ D+NDN P F + EN P SV+++ ATD D
Sbjct: 862 GGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEMRATDLDD 921
Query: 336 ---GENGEFTYQL 345
G N TY +
Sbjct: 922 PNVGANAILTYSI 934
Score = 43.6 bits (98), Expect = 0.043
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 11/126 (8%)
Query: 1365 KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG-YQVMQLKGAIGHHPTASRTVRADTD 1423
+V+V I DVN+N P F P A P P G ++ L+ H + R V
Sbjct: 87 QVIVGINDVNNNKPVFLEVRGPRGRA-PGVGPQGPLPLLHLRLFPQCHNYSQRAV----- 140
Query: 1424 ELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQ--APRFAIDPVSGTVRVVAALAR 1481
V + G+ QA D+D+G+N ++Y I++ + F IDP +G + + R
Sbjct: 141 --VLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPDAGYITTTVSFDR 198
Query: 1482 DAGRVF 1487
+ R F
Sbjct: 199 ERQREF 204
Score = 39.1 bits (87), Expect = 0.92
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 472 NAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTG--TVSVAESPILE 529
N GT + +V+A D DLG NG V Y + ++S F I+P+ G T +V+ +
Sbjct: 144 NQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDG--VSSGFHIDPDAGYITTTVSFDRERQ 201
Query: 530 GRHALFVEASDQPANP 545
L V A+DQ P
Sbjct: 202 REFTLSVTATDQADEP 217
>UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio
"Protocadherin2-gamma-v5-A.; n=3; Clupeocephala|Rep:
Homolog of Brachydanio rerio "Protocadherin2-gamma-v5-A.
- Takifugu rubripes
Length = 715
Score = 111 bits (268), Expect = 1e-22
Identities = 71/196 (36%), Positives = 103/196 (52%), Gaps = 9/196 (4%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
QKPLDRE+ + +IA + G +G + I + D NDN PVF + Y+ IMEN+
Sbjct: 202 QKPLDRERHPHLSLKLIA-VDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIMENT 260
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGVVKFIGDSLDREK 857
KIGT + + ATDAD G L Y+L G E+F +DE+TG + G +D EK
Sbjct: 261 KIGTNVV---TVNATDADSGIYGLITYSLSKMKGGAAEIFTIDESTGAITVSG-PIDYEK 316
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFT 917
Y++ + ARD GGL+ ++++ + D NDN P N I+ +S + L+ F
Sbjct: 317 DRKYEVRVEARDRGGLTGTSKVVFDVSDVNDNPPVINVIDADSDKNGQIKCSLDRKLPFK 376
Query: 918 IIEVKPKNKFALDVDQ 933
IE N + L DQ
Sbjct: 377 -IESSLTNYYNLISDQ 391
Score = 90.6 bits (215), Expect = 3e-16
Identities = 99/378 (26%), Positives = 160/378 (42%), Gaps = 47/378 (12%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQ 277
A D D+G A Y L + L + +GS ++E L LD E + + ++ V
Sbjct: 162 ADDMDVGQNALQNYVLSQNENFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVD 221
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
P ++ ++I +LD NDN+P F Y SI+EN G +V+ V ATD D G
Sbjct: 222 GG---TPQRSGTVNIDITVLDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGI 278
Query: 338 NGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMK------------- 380
G TY L KG F+ID +G +TV +++ +R++
Sbjct: 279 YGLITYSLSKMKGGAAEIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKV 338
Query: 381 ---VYAKETNPSVVGTF-ADSQRIAKW-----RRQPLETNAPLEKTTYVFPDKVGTKTEN 431
V NP V+ ADS + + R+ P + + L + D+ + E+
Sbjct: 339 VFDVSDVNDNPPVINVIDADSDKNGQIKCSLDRKLPFKIESSLTNYYNLISDQFFDR-ES 397
Query: 432 IEYYD----------EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
+ Y+ L + + + + D NDN P+F + + +++N+ GT I
Sbjct: 398 VSKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSP-GTSIFT 456
Query: 482 VKAVDPDLGQNGMVLYDLQRT--SNLTITSPFKINPNTGTVSVAESPILEGRHAL--FVE 537
V A D D QN + Y L+ T S I+S +N G +S A S E L V+
Sbjct: 457 VSARDSDWNQNARISYILEETHISGSPISSYLSLNSENGVISAARSFDYEQIKELQIVVK 516
Query: 538 ASDQPANPSERRYSLAVV 555
A D + P S+ ++
Sbjct: 517 AQDGGSPPLSSNVSVKIL 534
Score = 86.2 bits (204), Expect = 6e-15
Identities = 112/476 (23%), Positives = 192/476 (40%), Gaps = 53/476 (11%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY-EFSMKSNAKVGTVIGKVKAVDPDL 489
+IE E + + V +LD ND+ PVF + + + +A GT A D D+
Sbjct: 108 SIEVILENPLELHRITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDV 167
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA-LFVEASDQPANPSER 548
GQN + Y L + N + + + V + P+ RH L ++ +R
Sbjct: 168 GQNALQNYVLSQNENFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQR 227
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
V I++T ++P F + Y+ + N IGT+V + DA +
Sbjct: 228 S---GTVNIDIT--VLDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLI 282
Query: 607 SYDL--LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV 664
+Y L + G + F ++E +G ITV + Y+ A ++ L+ +
Sbjct: 283 TYSLSKMKGGAAEI-FTIDESTGAITVSGPIDYEKDRKYEVRVEA-RDRGGLTGTSKVVF 340
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V DVND + P+I N+ + G ++ + +
Sbjct: 341 DVSDVND---------NPPVI------------------NVIDADSDKNGQIKCSLDRKL 373
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ ++ + + + DRE Y +TV A + G + + + I D NDN
Sbjct: 374 PFKIESSLTNYYNLISDQFFDRESVSKYNITVTAT-DSGTPPLSTSTTLHLIISDVNDNA 432
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEG-KEMFD 838
P+FE +Y +I+EN+ GT I + A D+D NA Y L G
Sbjct: 433 PLFEKQSYSAYIVENNSPGTSI---FTVSARDSDWNQNARISYILEETHISGSPISSYLS 489
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
++ GV+ S D E+ ++ + A+D G LSS + I+I D+NDN P+
Sbjct: 490 LNSENGVIS-AARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQ 544
Score = 79.8 bits (188), Expect = 5e-13
Identities = 112/450 (24%), Positives = 186/450 (41%), Gaps = 65/450 (14%)
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L + A+DGG + +++ + V D ND+ PVF ++ Y ++ E + V+ATDA
Sbjct: 215 LKLIAVDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDA 274
Query: 1073 DFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D G +TY + F I TG ++V+G +D E + KY + V ARD G
Sbjct: 275 DSGIYGLITYSLSKMKGGAAEIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRG---G 331
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
DVNDN P D AD N K +++
Sbjct: 332 LTGTSKVVFDVSDVNDNPPVINVID---------ADSDKNGQI---------KCSLDRKL 373
Query: 1191 P--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE 1248
P I +++ + +D + + Y++ G P LS++ L + ++DV D
Sbjct: 374 PFKIESSLTNYYNLISDQFFDRESVSKYNITVTATDS--GTPPLSTSTTLHLIISDVND- 430
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNE---NDTDIRR 1304
+ P+F + Y I EN + + +++ + N R YIL E + + I
Sbjct: 431 ----NAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNARISYILEETHISGSPISS 486
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
++ NG + RS D E +++V+A+ P P++ +V V
Sbjct: 487 YLSLNSENGVISAARSFDYEQIKELQIVVKAQ----DGGSP----PLSSNV-------SV 531
Query: 1365 KVVVRIKDVNDNSPK----FTNGNRPLVTAIPTTAPFGYQVMQLKGA---IGHHPTASRT 1417
K++ I+D NDN P+ G + +P +A GY V ++ G + S
Sbjct: 532 KIL--IQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYK 589
Query: 1418 VRADTDELVFFERLSLNG--LTSPQATDSD 1445
++ TD +F L NG T Q TD D
Sbjct: 590 LQKATDRALFEVGLQ-NGEIRTIRQVTDKD 618
Score = 69.3 bits (162), Expect = 8e-10
Identities = 58/199 (29%), Positives = 95/199 (47%), Gaps = 19/199 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+++ N P GT+I ++A D D N +I Y E +I S +S+ Y +N
Sbjct: 443 YIVENNSP-GTSIFTVSARDSDWNQNARISYILE-ETHISGSPISS-------YLSLNSE 493
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+G + ARS E E ++ + A DGG+ L+ N+SV++ ++D ND+ P
Sbjct: 494 NGVISAARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGG 553
Query: 1054 VEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
A+ R ++ KV A D D GQNA L+Y +Q + FE+ G + +
Sbjct: 554 SMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTIRQ 613
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ + K L+V+ DNG
Sbjct: 614 VTDKDAVKQRLSVIVEDNG 632
Score = 67.7 bits (158), Expect = 2e-09
Identities = 66/217 (30%), Positives = 94/217 (43%), Gaps = 42/217 (19%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN IGT ++ +NA D DSG+ G I Y SK+ A E+ F I+E G
Sbjct: 256 IMENTKIGTNVVTVNATDADSGIYGLITYSL--------SKMKGGAAEI---FTIDESTG 304
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V+ + E + + + + A D G L V V DVND+ PV
Sbjct: 305 AITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKVVFDVSDVNDNPPV------------- 351
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-SPLTGVLSVNGE--LDRETED 1114
++ DAD +N + + D LPF+I S LT ++ + DRE+
Sbjct: 352 ---------INVIDADSDKNGQIKCSL---DRKLPFKIESSLTNYYNLISDQFFDRESVS 399
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
KY +TV A D+G DVNDN+P F
Sbjct: 400 KYNITVTATDSG-TPPLSTSTTLHLIISDVNDNAPLF 435
Score = 58.8 bits (136), Expect = 1e-06
Identities = 50/205 (24%), Positives = 93/205 (45%), Gaps = 19/205 (9%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
+N +D DS NGQI+ + ++ P K+ + Y +I+++ S+ S+
Sbjct: 352 INVIDADSDKNGQIKCSLDRKL---PFKIESSLTNY--YNLISDQF---FDRESV---SK 400
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ + ++A D G L+ + ++ + + DVND+ P+F+K Y+ + E + V A
Sbjct: 401 YNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSAR 460
Query: 1071 DADFGQNANLTYFIQP-----SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
D+D+ QNA ++Y ++ S ++ GV+S D E + K + VV +
Sbjct: 461 DSDWNQNARISYILEETHISGSPISSYLSLNSENGVISAARSFDYE-QIKELQIVVKAQD 519
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPK 1150
G D NDN P+
Sbjct: 520 GGSPPLSSNVSVKILIQDQNDNPPQ 544
Score = 53.2 bits (122), Expect = 5e-05
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 11/163 (6%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKL-FSLDSVNGSLF-LEKELDLDAEHNLQANTF 272
P I+ ID D ++ L DRKL F ++S + + L + D E + +
Sbjct: 349 PPVINVIDADSDKNGQIKCSL----DRKLPFKIESSLTNYYNLISDQFFDRE---SVSKY 401
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ V A+ P + + + + D+NDN P FE Y+ IVEN G S+ V A D
Sbjct: 402 NITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARD 461
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
D +N +Y L++ S P S +L++ ++ + A S
Sbjct: 462 SDWNQNARISYILEETH--ISGSPISSYLSLNSENGVISAARS 502
Score = 52.4 bits (120), Expect = 9e-05
Identities = 51/159 (32%), Positives = 74/159 (46%), Gaps = 18/159 (11%)
Query: 770 IYQVTIYIEDENDNPPVF----EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
++++T+ + D ND+ PVF +H + E I E++ GT+ + A D D G NAL
Sbjct: 119 LHRITVEVLDINDHAPVFPNQDKHVSLE--ISESALTGTQFPLQG---ADDMDVGQNALQ 173
Query: 826 MYTLFGEG----KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAEL 879
Y L K+ + D + V + LDRE+ L L+A D G S +
Sbjct: 174 NYVLSQNENFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNI 233
Query: 880 IIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTI 918
I + D NDN P FNQ K I TK+ GT T+
Sbjct: 234 DITVLDANDNVPVFNQ--SVYKASIMENTKI-GTNVVTV 269
Score = 48.0 bits (109), Expect = 0.002
Identities = 36/122 (29%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V+V++ + D NDN P V P ++ + +A VG ++ KV AVD D GQN
Sbjct: 525 LSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNA 584
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ Y LQ+ ++ + N T+ V + ++ R ++ VE + QP+ + ++
Sbjct: 585 WLSYKLQKATDRALFEVGLQNGEIRTIRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNV 644
Query: 553 AV 554
AV
Sbjct: 645 AV 646
Score = 47.2 bits (107), Expect = 0.003
Identities = 79/294 (26%), Positives = 114/294 (38%), Gaps = 48/294 (16%)
Query: 938 FLIPENIPIGTTIIKLN---ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
+ IPE + G+ I L LDL +G+ R + ++L+ D K V+
Sbjct: 36 YSIPEEMKKGSVIGNLAQDLGLDLKRLRSGRARIVTGENIQY--TELNTD----KGILVV 89
Query: 995 NERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF--KKTWYNF 1052
NER + + P S F + + + L+ + V V D+NDH PVF + +
Sbjct: 90 NERIDREQLCGDVTPCS-FSIEVILENPLELH---RITVEVLDINDHAPVFPNQDKHVSL 145
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG----VLSVNGEL 1108
+ E+ T A D D GQNA Y + ++ + + + G + + L
Sbjct: 146 EISESALTGTQFPLQGADDMDVGQNALQNYVLSQNENFILKQHANPDGSKYVEMVLQKPL 205
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
DRE L ++A D G D NDN P F
Sbjct: 206 DRERHPHLSLKLIAVDGG-TPQRSGTVNIDITVLDANDNVPVFN---------------- 248
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK 1222
+SV YKA+I EN IGT V V A D D GLI YSL + K
Sbjct: 249 -----QSV-----YKASIMENTKIGTNVVTVNATDAD--SGIYGLITYSLSKMK 290
Score = 46.0 bits (104), Expect = 0.008
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 19/169 (11%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D A + Y L ISG+ + SL+S NG + + D + LQ
Sbjct: 457 VSARDSDWNQNARISYILEETHISGSPISSYLSLNSENGVISAARSFDYEQIKELQ---- 512
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN----GFSVL 326
+ V+A +P ++ V+I + D NDN P+ + V + E +P G+ V
Sbjct: 513 -IVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVT 571
Query: 327 QVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREA 373
+V+A D D G+N +Y+L + F + ++G + Q V D++A
Sbjct: 572 KVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTIRQ-VTDKDA 619
Score = 41.1 bits (92), Expect = 0.23
Identities = 50/213 (23%), Positives = 91/213 (42%), Gaps = 13/213 (6%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAE-HNLQANTFVLQVQASQLNNPLKTAQA 290
R +++G + + L++ G L + + +D + ++ +F ++V L NPL+
Sbjct: 66 RARIVTGENIQYTELNTDKGILVVNERIDREQLCGDVTPCSFSIEVI---LENPLELH-- 120
Query: 291 RVEIELLDLNDNLPEF--EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
R+ +E+LD+ND+ P F + ++ I E+ G A D D G+N Y L
Sbjct: 121 RITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQN 180
Query: 349 KGAF---SIDP-RSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIAKW 403
+ +P S ++ + Q LDRE H L +K+ A + P GT +
Sbjct: 181 ENFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDA 240
Query: 404 RRQPLETNAPLEKTTYVFPDKVGTKTENIEYYD 436
N + K + + K+GT + D
Sbjct: 241 NDNVPVFNQSVYKASIMENTKIGTNVVTVNATD 273
>UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 2779
Score = 111 bits (268), Expect = 1e-22
Identities = 127/452 (28%), Positives = 200/452 (44%), Gaps = 40/452 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + L D NDN P+F P N Y +++ K + V A D D G G V Y +
Sbjct: 627 ISIRLKDVNDNWPIFYP-NEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI----- 680
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
L+ +S F INP TG V A+ P+ GR L V A D SE ++ + I+ + TK
Sbjct: 681 LSESSSFSINPVTGEV-FAQKPLARGRFHLVVSAKDGGGQSSENSANIHITVID--KDTK 737
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
P F + YE ++ G ++G + + V Y + G ++ F+++E
Sbjct: 738 -----TPQFSRSKYEIRTTEDILPGIAIGSVGA-----MSKVKYSIYSG-DQDHNFSIDE 786
Query: 625 RSGVITVVDDLSRY-NRPMYDFEAVALQENANL-SIVTNATVHVVDVNDERGVLLKGAHS 682
+G I V +RY + ++D V L A L S +N T V+ + D + + S
Sbjct: 787 DTGKIYV----TRYLDADVHD--TVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSS 840
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDGTIFTQ 741
+ ++E+ + + F+ +S G VR+ I + + G + T
Sbjct: 841 LVEISIRED---LKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTG 897
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LD E Y++ V A + G+ + + I++ D NDN P FE + Y ++ENS
Sbjct: 898 SLLDYEATRNYKLRVKAT-DLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSP 956
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
T + + A D D N +Y + G E F +DE G V + S+DRE
Sbjct: 957 PKTIV---GKVVARDKDSLENGQIVYRI-TNGSEYFGIDEKLGNV-YTKRSIDREVISHV 1011
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+S+VA D G SS A I + D NDN P
Sbjct: 1012 DISIVAEDKGVPPRSSTASARISVLDVNDNPP 1043
Score = 95.5 bits (227), Expect = 1e-17
Identities = 119/457 (26%), Positives = 200/457 (43%), Gaps = 26/457 (5%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ ++DANDN PVF S Y S+ +N +G+ + V+A D D+G+N + YD+++TS
Sbjct: 221 IEIIDANDNAPVFSRSR-YTASVSANISIGSHLITVQATDADIGENSRISYDIKKTS-AP 278
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
S F I+ +G ++ S + H + V ASD +PS S AVVTI V T +
Sbjct: 279 SNSNFAIS-QSGVITTTASLLPASTHDVIVVASDH-GSPS--LSSSAVVTITVLGSTLSS 334
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERS 626
P ++ + N +G+ V RV+ A + D L+ G P ++
Sbjct: 335 PPLDIIWLVESNSAHLMENSTLGSIVA--RVSIAQQYRDTKLRLI-GSSALCPQQTDQAH 391
Query: 627 GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
+ ++ + L+++ + I + + D+ND HS I
Sbjct: 392 VYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQLLTIGDINDN----APQWHSSQI- 446
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
H+ N G T G G +R+ + + + V+ D E G IF +D
Sbjct: 447 HISLNRTQG--GSRTLTAKDPDLGQ-NGWIRYSVLDTELVSID---KETGRIFVPNTIDC 500
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
+ V AE + G + + QV + D PP FE A ++ I E++ IGT +
Sbjct: 501 NIGSEIKFRVRAE-DGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCL 559
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ A ++ G + Y+L + E VD +G V I + D EK+ Y+ +++
Sbjct: 560 VK---VVANNSQCGNSKRIRYSLQNQ-DEHLTVDTMSGTV-CIQKTFDFEKQKSYQTTVI 614
Query: 867 ARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
A + +S + + I + D NDN P F E + VR
Sbjct: 615 ATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVR 651
Score = 92.3 bits (219), Expect = 9e-17
Identities = 63/233 (27%), Positives = 117/233 (50%), Gaps = 14/233 (6%)
Query: 156 NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFP 215
++DVH +++ + ES+ V++ + D++ +F ++ I +++
Sbjct: 798 DADVHDTVLLNIQATLPSGESNQTQVVIF--IEDHNDNPPQFSSSLVEIS--IREDLKLH 853
Query: 216 EPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
EP + + D+D +RY +IS + +D G L LD +A N +
Sbjct: 854 EPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRN-----Y 908
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L+V+A+ L P +++ + I +LD+NDN PEFE +Y + ++EN P V +V+A D
Sbjct: 909 KLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARD 968
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
KD ENG+ Y++ + F ID + G V + +DRE S + + + A++
Sbjct: 969 KDSLENGQIVYRITNGSEYFGIDEKLG--NVYTKRSIDREVISHVDISIVAED 1019
Score = 81.4 bits (192), Expect = 2e-13
Identities = 89/324 (27%), Positives = 146/324 (45%), Gaps = 29/324 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
I N ++ +++ ++DVNDN PIF YH+TV E P E+ + + A S T
Sbjct: 614 IATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVRE-GPKPEEPLLVVSASDMDSGT 672
Query: 130 IP------LTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
L+ +I KP + +VS D G +SS +
Sbjct: 673 FGEVSYHILSESSSFSINPVTGEVFAQKPLARGR--FHLVVSAKDGGG---QSSENSANI 727
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
V+D D +F R ++IL P AI +G + ++Y + SG+
Sbjct: 728 HITVIDKDTKTPQFSRSKYEI--RTTEDIL---PGIAIGS-VGAMSKVKYSIYSGDQDHN 781
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS+D G +++ + LD D +T +L +QA+ + ++ Q +V I + D NDN
Sbjct: 782 FSIDEDTGKIYVTRYLDADVH-----DTVLLNIQATLPSG--ESNQTQVVIFIEDHNDNP 834
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWL 361
P+F ISI E+L V A+DKD+ +NGE Y + P + ID +G L
Sbjct: 835 PQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQL 894
Query: 362 TVRNQTVLDREAHSSLRMKVYAKE 385
+ ++LD EA + +++V A +
Sbjct: 895 S--TGSLLDYEATRNYKLRVKATD 916
Score = 79.4 bits (187), Expect = 7e-13
Identities = 113/464 (24%), Positives = 188/464 (40%), Gaps = 46/464 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + V LLD P F + L++ + + +GT + KV A + G + + Y
Sbjct: 520 LSTDLQVVADLLDTESKPPQFEKA-LWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYS 578
Query: 499 LQ-RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
LQ + +LT+ + +GTV + ++ E + + AN SE SL + +
Sbjct: 579 LQNQDEHLTVDTM------SGTVCIQKTFDFEKQKSYQTTVIATNAN-SETSTSLISIRL 631
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWV--GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
K + P F Y V G V D+ +VSY +L
Sbjct: 632 ------KDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHIL---S 682
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
E F++ +G + L+R + V+ ++ S +A +H+ ++ +
Sbjct: 683 ESSSFSINPVTGEVFAQKPLARGRFHL----VVSAKDGGGQSSENSANIHITVIDKDTKT 738
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
I ++ G AIG + V++ I + D + +I ED
Sbjct: 739 PQFSRSKYEIRTTEDILPGIAIGSV----------GAMSKVKYSIYSG-DQDHNFSIDED 787
Query: 736 -GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G I+ + LD + D + + A G + QV I+IED NDNPP F + E
Sbjct: 788 TGKIYVTRYLDADVHDTVLLNIQATLPSGESNQT---QVVIFIEDHNDNPPQFSSSLVEI 844
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSL 853
I E+ K+ +++A+D D+ N Y++ ++D+ TG + G L
Sbjct: 845 SIREDLKLHEPF---YVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLS-TGSLL 900
Query: 854 DREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
D E YKL + A D G SS L I + D NDN PEF +
Sbjct: 901 DYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEK 944
Score = 78.2 bits (184), Expect = 2e-12
Identities = 113/476 (23%), Positives = 202/476 (42%), Gaps = 39/476 (8%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMK-SNAKVGTVIGKVKAVDP 487
T I+ D +F N+ + + D NDN P F LY+ ++ + G K++A
Sbjct: 1999 TLTIKATDGSFDTFTNLTIFVSDINDNAPTF-SKPLYQTTVSPATFSPGQPFAKIEA--H 2055
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSE 547
DL G + Y L + S+ S F++ P +G + + P R+ + V A+D PS
Sbjct: 2056 DLDARGALTYSLGQGSS----SIFRVAPESGALFMKVLPPAGERYLVTVTATDNGV-PS- 2109
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS 607
+S +V + V G + D P F A + F V N IG +G + E +
Sbjct: 2110 --FSTSV-PVSVIIG-EAEPTDKPGFEKAEFRFEVMENSKIGLQIGNL---SGEESREFH 2162
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y + E F+++ + G + V + R R ++F+ V + S HV+
Sbjct: 2163 YRI-QDPEASKIFSID-KFGRLFVAGPIDREQRATHEFQ-VEIDNEMMTSQKVQCKCHVI 2219
Query: 668 --DVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
D ND V A+ +K++ A G IGQI ++ S G V + I +
Sbjct: 2220 VLDENDNLPVFTSVAY---YLSLKDSMAHGQKIGQIMASDQDS---GENGRVSYRILSGN 2273
Query: 725 DVTDDIAIAEDGTI----FTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIED 779
D+ + G+I + LD +++ V A + + G QV++ +
Sbjct: 2274 DLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSS 2333
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
+ + P F YE ++E++ +GT ++ I+A++ N +Y+L E + +
Sbjct: 2334 WSGSAPFFVLPVYEVHVLEDTSVGTVLQK---IRASNRLGMRNDGLLYSL-KEHQGKLGI 2389
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
D TG + + LD E + + + L D G S+ L I++ ++ P F +
Sbjct: 2390 DVKTGELT-LKTHLDWESEPIISMYLSVSDGNGRSAVVPLKIVVEPVDEFAPVFTK 2444
Score = 75.4 bits (177), Expect = 1e-11
Identities = 106/485 (21%), Positives = 199/485 (41%), Gaps = 52/485 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+T+ D NDN P + S ++ ++ T+ K DPDLGQNG + Y + T ++
Sbjct: 429 LTIGDINDNAPQWHSSQIHISLNRTQGGSRTLTAK----DPDLGQNGWIRYSVLDTELVS 484
Query: 507 ITSPFK--INPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
I PNT ++ E + + E PA ++ + ++ E
Sbjct: 485 IDKETGRIFVPNTIDCNIGS----EIKFRVRAEDGGSPALSTDLQVVADLLDTE------ 534
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVPFAV 622
+KP P F A ++ + + IGT + ++ N++ N + Y L + E V
Sbjct: 535 -SKP--PQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEH---LTV 588
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+ SG + + + Y +A N+ S + ++ + DVND +
Sbjct: 589 DTMSGTVCIQKTFDFEKQKSYQTTVIATNANSETS-TSLISIRLKDVNDNWPIFY----- 642
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
P +H+ + + S + G V + I ++ + G +F QK
Sbjct: 643 PNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSSFSINPVT--GEVFAQK 700
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PL R + + + V A+ + G S + I + D++ P F + YE E+
Sbjct: 701 PLARGR---FHLVVSAK-DGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILP 756
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
G I G + Y+++ G+ F +DE+TG + ++ LD +
Sbjct: 757 GIAI----------GSVGAMSKVKYSIYSGDQDHNFSIDEDTGKI-YVTRYLDADVHDTV 805
Query: 862 KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
L++ A G S++ +++I I D NDN P+F+ ++ I + KL+ F +++
Sbjct: 806 LLNIQATLPSGESNQTQVVIFIEDHNDNPPQFS--SSLVEISIREDLKLH--EPFYVVQA 861
Query: 922 KPKNK 926
K+K
Sbjct: 862 SDKDK 866
Score = 73.3 bits (172), Expect = 5e-11
Identities = 90/337 (26%), Positives = 160/337 (47%), Gaps = 35/337 (10%)
Query: 436 DEQLMSFVNVE----VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
D ++M+ V+ V +LD NDN PVF S Y S+K + G IG++ A D D G+
Sbjct: 2203 DNEMMTSQKVQCKCHVIVLDENDNLPVFT-SVAYYLSLKDSMAHGQKIGQIMASDQDSGE 2261
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE---SPILEGRHA---LFVEASDQPANP 545
NG V Y + ++L I + +NP+TG++ + E + + E +A + VEA D +P
Sbjct: 2262 NGRVSYRILSGNDLNIVT---LNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDH-GHP 2317
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF-EQN 604
+ AV ++V+ P F+ YE V + +GT + +IR ++ +N
Sbjct: 2318 AR----AAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRN 2373
Query: 605 DVSYDLLHGYEEGV-PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
D LL+ +E ++ ++G +T+ L + P+ +++ + S V
Sbjct: 2374 D---GLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISM-YLSVSDGNGRSAVVPLK 2429
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+ V V++ V K +++ I AG ++GQ+ + G G V++ I+++
Sbjct: 2430 IVVEPVDEFAPVFTKSSYTLQI--PISTPAGESVGQMQAIDED---GGVHGVVKYSISDR 2484
Query: 724 QDVTDDIAIAE-DGTIFTQKPL-DREKRDVYRMTVIA 758
Q + I E G I QKPL R + ++TV+A
Sbjct: 2485 QST---VKIEEHTGIIRLQKPLVSRRNLTIEQITVVA 2518
Score = 66.9 bits (156), Expect = 4e-09
Identities = 58/214 (27%), Positives = 90/214 (42%), Gaps = 20/214 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++ + + A D D NG++RY S P S + D G
Sbjct: 846 IREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSH--PGSSIEIDQFT-----------G 892
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L E+ ++L + A D G + N+++ + V DVND+ P F+K+WY V
Sbjct: 893 QLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVL 952
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + ++GKV A D D +N + Y I ++ F I G + +DRE
Sbjct: 953 ENSPPKTIVGKVVARDKDSLENGQIVYRI--TNGSEYFGIDEKLGNVYTKRSIDREVISH 1010
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+++VA D G DVNDN P
Sbjct: 1011 VDISIVAEDKG-VPPRSSTASARISVLDVNDNPP 1043
Score = 65.3 bits (152), Expect = 1e-08
Identities = 35/115 (30%), Positives = 59/115 (51%), Gaps = 1/115 (0%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQ-ANTFVLQVQASQLNNPLKTAQA 290
R+ ++ GN +F L S + L+ +L ++ + + + + + L ++A P K Q
Sbjct: 158 RFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQL 217
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
R IE++D NDN P F Y S+ N+ G ++ V ATD D GEN +Y +
Sbjct: 218 RCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDI 272
Score = 65.3 bits (152), Expect = 1e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D DLG +RY ++ D +L S+D G +F+ +D + ++ +V+A
Sbjct: 462 AKDPDLGQNGWIRYSVL---DTELVSIDKETGRIFVPNTIDCNIGSEIK-----FRVRAE 513
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P + +V +LLD P+FE + + I E+ P G +++V+A + G +
Sbjct: 514 DGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSK 573
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
Y L + ++D SG TV Q D E S + V A N
Sbjct: 574 RIRYSLQNQDEHLTVDTMSG--TVCIQKTFDFEKQKSYQTTVIATNAN 619
Score = 65.3 bits (152), Expect = 1e-08
Identities = 45/172 (26%), Positives = 85/172 (49%), Gaps = 5/172 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A DQD G + Y ++SGND + +L+ GS+ L + D + A T+ + V+
Sbjct: 2252 IMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNA-TWQILVE 2310
Query: 278 ASQLNNPLKTAQARVEIEL--LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A +P + A +V++ L + + P F + Y + ++E+ G + ++ A+++
Sbjct: 2311 ARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLG 2370
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
N Y L + +G ID ++G LT++ T LD E+ + M + + N
Sbjct: 2371 MRNDGLLYSLKEHQGKLGIDVKTGELTLK--THLDWESEPIISMYLSVSDGN 2420
Score = 64.9 bits (151), Expect = 2e-08
Identities = 52/207 (25%), Positives = 99/207 (47%), Gaps = 13/207 (6%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y + K+FS+D G LF+ +D + Q T QV+ + Q +
Sbjct: 2163 YRIQDPEASKIFSIDKF-GRLFVAGPIDRE-----QRATHEFQVEIDNEMMTSQKVQCKC 2216
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKG 350
+ +LD NDNLP F Y +S+ +++ +G + Q+MA+D+D GENG +Y++ +
Sbjct: 2217 HVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLN 2276
Query: 351 AFSIDPRSGWLTVR--NQTVLDREAHSSLRMKVYAKE-TNP--SVVGTFADSQRIAKWRR 405
+++P +G + + N LD +++ ++ V A++ +P + VG S +++ W
Sbjct: 2277 IVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSG 2336
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENI 432
P+ + + VGT + I
Sbjct: 2337 SAPFFVLPVYEVHVLEDTSVGTVLQKI 2363
Score = 62.9 bits (146), Expect = 7e-08
Identities = 65/277 (23%), Positives = 125/277 (45%), Gaps = 17/277 (6%)
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRA 146
I D+NDN P + + H++++ T G + +G + I +V + D
Sbjct: 431 IGDINDNAPQWHSSQIHISLNR-TQGGSRTLTAKDPDLGQNGWIRYSVLDTELVSIDKET 489
Query: 147 FDRDKPNTPNSDVHYSI---VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMA 203
PNT + ++ I V D G AL + + ++ +LD ++ +F+ +
Sbjct: 490 GRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTD---LQVVADLLDTESKPPQFEKALWQ 546
Query: 204 SGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD 262
I + A + G +RY L N + ++D+++G++ ++K D +
Sbjct: 547 VEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL--QNQDEHLTVDTMSGTVCIQKTFDFE 604
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG 322
+ + Q T V+ A+ +T+ + + I L D+NDN P F + Y++++ E
Sbjct: 605 KQKSYQ--TTVIATNANS-----ETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPE 657
Query: 323 FSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
+L V A+D D G GE +Y + +FSI+P +G
Sbjct: 658 EPLLVVSASDMDSGTFGEVSYHILSESSSFSINPVTG 694
Score = 62.9 bits (146), Expect = 7e-08
Identities = 49/162 (30%), Positives = 66/162 (40%), Gaps = 3/162 (1%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I+E G + V R L + LNI A ++ V +F++D ND+ P F +
Sbjct: 782 FSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSL 841
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
++ E V A+D D +N + Y I S EI TG LS LD
Sbjct: 842 VEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLD 901
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E Y L V A D G DVNDN+P+F
Sbjct: 902 YEATRNYKLRVKATDLG-IPPRSSNMTLFIHVLDVNDNAPEF 942
Score = 62.5 bits (145), Expect = 9e-08
Identities = 69/267 (25%), Positives = 111/267 (41%), Gaps = 22/267 (8%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA-VEERSGVI 629
P F +F V + IGT +G I E Y ++ E+ F V+ERSG I
Sbjct: 20 PTFCQCLTKFTVPESAQIGTRIGWIS-GKREESAAPKYFVVFPDEQTSKFLKVDERSGEI 78
Query: 630 TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
+ + L R +D AV ++E+ + +V+V+DE A + +
Sbjct: 79 STIAHLDYEKRSKFDIVAVKVEESGETIDI------LVEVDDENDNAPSFADQVVKLEIS 132
Query: 690 ENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-------DGTIFTQK 742
E A +G F + +V + Q +V + +A +
Sbjct: 133 EF---AQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNG 189
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDRE RD Y + + A+ + G + G + +I I D NDN PVF + Y + N I
Sbjct: 190 QLDREFRDKYELLIEAQ-DGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISI 248
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTL 829
G+ + ++ATDAD G N+ Y +
Sbjct: 249 GSHL---ITVQATDADIGENSRISYDI 272
Score = 62.1 bits (144), Expect = 1e-07
Identities = 95/392 (24%), Positives = 157/392 (40%), Gaps = 49/392 (12%)
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
L A D D G NG IRY + +S D E R FV N ++ SE
Sbjct: 460 LTAKDPDLGQNGWIRYSV-----LDTELVSIDK-ETGRIFVPNTIDCNI--------GSE 505
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ + A DGG+ L+ ++ V + D P F+K + + E L KV A
Sbjct: 506 IKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVAN 565
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
++ G + + Y +Q D L + ++G + + D E + Y TV+A +
Sbjct: 566 NSQCGNSKRIRYSLQNQDEHL--TVDTMSGTVCIQKTFDFEKQKSYQTTVIATN---ANS 620
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFD-ELLEWKHPEADE----LSNHNFESVMMIPVYKAT 1185
DVNDN P FY + L + P+ +E +S + +S V
Sbjct: 621 ETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI 680
Query: 1186 IEENA--PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
+ E++ I +VFA + G ++ S Q S ++A + +TV
Sbjct: 681 LSESSSFSINPVTGEVFAQKP--LARGRFHLVVSAKDGGGQ------SSENSANIHITVI 732
Query: 1244 DVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIR 1303
D + + P F YE+ E++ + + S+ K++Y I + D D
Sbjct: 733 D-----KDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAMS-----KVKYSIYS-GDQD-- 779
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
F ID G +Y+ R D +V DT + ++A
Sbjct: 780 HNFSIDEDTGKIYVTRYLDADVHDTVLLNIQA 811
Score = 61.3 bits (142), Expect = 2e-07
Identities = 113/513 (22%), Positives = 210/513 (40%), Gaps = 48/513 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + + D NDN P F S+L E S++ + K+ V+A D D +NG V Y + +
Sbjct: 823 VVIFIEDHNDNPPQF-SSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHP 881
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S +I+ TG +S E + L V+A+D P +L + ++V
Sbjct: 882 ---GSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDV--- 935
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEEGVPF 620
+ P+F + Y V N T VG++ R D+ E + Y + +G E F
Sbjct: 936 ----NDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEY---F 988
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
++E+ G + + R D VA + S +A + V+DVND L
Sbjct: 989 GIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCL-- 1046
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAEDGTI 738
+ +PI+ AG+ + T ++ G G+V + Q + + +G +
Sbjct: 1047 SITPIVV-----PAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSSL---FVVKSNGDV 1098
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
+ ++ L+ R++VI ++GV + + V + I + + + E ++ +I
Sbjct: 1099 YLRRQLNASDERHQRLSVIVS-DQGVPRKSVVCHVPVRISKGSADIQIQE--PFQKYIEI 1155
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
T ++ + AT G ++ + + E F + E GV+ I + R
Sbjct: 1156 PKSCPTGCRL-TTLNAT----GVSSWLIQS--SEISNHFAIRE--GVLFMISHPIHRPP- 1205
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV--RIHRETKLNGTAGF 916
Y L +V D +L ++ E NK E +I +++ + +I R + + F
Sbjct: 1206 --YSLVIVLSDKNDRQKSIQLRVLASGEAANKEETIRISDSNSIGTKIGRLGEKSADGSF 1263
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTT 949
+ L++DQ G L + + + G T
Sbjct: 1264 -FYRFSSEESCPLELDQTGGLLYLADGLRRGDT 1295
Score = 60.9 bits (141), Expect = 3e-07
Identities = 47/189 (24%), Positives = 85/189 (44%), Gaps = 22/189 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE+ PIGT ++K+ A + G + +IRY ++ + ++ G
Sbjct: 549 IPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQ---------------DEHLTVDTMSG 593
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V + ++ E + ++ + A + + + + +KDVND++P+F Y+ V E
Sbjct: 594 TVCIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREG 653
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
L V A+D D G ++Y I + F I+P+TG + L R ++
Sbjct: 654 PKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPLAR---GRFH 708
Query: 1118 LTVVARDNG 1126
L V A+D G
Sbjct: 709 LVVSAKDGG 717
Score = 59.3 bits (137), Expect = 8e-07
Identities = 67/272 (24%), Positives = 112/272 (41%), Gaps = 24/272 (8%)
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFK 1046
+ ++ ++ER G + L E + +I A+ + I + V V D ND+ P F
Sbjct: 64 QTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESGETIDILVEVDDENDNAPSFA 123
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP------LTG 1100
+ E TD D + + I + + F+++ L
Sbjct: 124 DQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQA 183
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
L VNG+LDRE DKY L + A+D G D NDN+P F
Sbjct: 184 DLVVNGQLDREFRDKYELLIEAQDGG-KPAKIGQLRCSIEIIDANDNAPVF-------SR 235
Query: 1161 KHPEADELSNHNFES-VMMIPVYKATIEENAPIGTTVAKVFA-NDTDFIGNGNGLILYS- 1217
A +N + S ++ + A I EN+ I + K A ++++F + +G+I +
Sbjct: 236 SRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTA 295
Query: 1218 --LPQRKNQ-----QNLGLPSLSSTAILMVTV 1242
LP + + G PSLSS+A++ +TV
Sbjct: 296 SLLPASTHDVIVVASDHGSPSLSSSAVVTITV 327
Score = 58.8 bits (136), Expect = 1e-06
Identities = 115/512 (22%), Positives = 199/512 (38%), Gaps = 57/512 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VT+ D NDN P S E + +++VG V+ + +A D D+GQNG ++L S
Sbjct: 1713 VRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDS- 1771
Query: 505 LTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ + P TG + + S + + L V P E+ +E++
Sbjct: 1772 ---SGSLDLVPETGDLVLRRLSSLQSWKIKLRVVDHGVPGLYVEK-------NLEISNRN 1821
Query: 564 KGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P +F+ Y S + G GQ E ++Y ++ G + F+V
Sbjct: 1822 PQTEAKAPLEFLKQTYL----STIDEGLPRGQFIAKLQPELAGLTYSIVEGNIDSA-FSV 1876
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
+ GVI +L R Y + + + I T V V ++ND
Sbjct: 1877 DS-EGVIRTNLELDREILERYSLKVIG--TGSGQQIGTRVDVRVNNLNDNVPSFPMSKPR 1933
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED--GTIFT 740
+ +++ S A +G N++ + FL+++ T + GTI
Sbjct: 1934 RVPENLRVGSYVATVGAKDVDNLAPLR-------YFLVSDSSGQTPTHFNIDQFTGTIHL 1986
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
PLD E + +T+ A S +TI++ D NDN P F Y+ +
Sbjct: 1987 TAPLDFEVLPEHTLTIKATDG----SFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSP-- 2040
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV--VKFIGDSLDREKK 858
T K D Y+L +F V +G +K + + +R
Sbjct: 2041 --ATFSPGQPFAKIEAHDLDARGALTYSLGQGSSSIFRVAPESGALFMKVLPPAGER--- 2095
Query: 859 IMYKLSLVARDTG--GLSSEAELIIMIGD-ENDNKPEFNQIE------ENSKVRIHRETK 909
Y +++ A D G S+ + ++IG+ E +KP F + E ENSK+ + +
Sbjct: 2096 --YLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGL-QIGN 2152
Query: 910 LNG--TAGFTIIEVKPKNKFALDVDQLGPLFL 939
L+G + F P+ +D+ G LF+
Sbjct: 2153 LSGEESREFHYRIQDPEASKIFSIDKFGRLFV 2184
Score = 58.0 bits (134), Expect = 2e-06
Identities = 50/190 (26%), Positives = 92/190 (48%), Gaps = 21/190 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN+ +G+ + + A D+D+ +RY S+ + + +F I++ G
Sbjct: 1935 VPENLRVGSYVATVGAKDVDN--LAPLRYFLVSD----------SSGQTPTHFNIDQFTG 1982
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + L E E L I A DG + + ++ +FV D+ND+ P F K Y V A
Sbjct: 1983 TIHLTAPLDFEVLPEHTLTIKATDG-SFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPA 2041
Query: 1058 QYT-RRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
++ + K++A D D LTY + + + F ++P +G L + ++ ++Y
Sbjct: 2042 TFSPGQPFAKIEAHDLD--ARGALTYSLGQGSSSI-FRVAPESGALFM--KVLPPAGERY 2096
Query: 1117 ILTVVARDNG 1126
++TV A DNG
Sbjct: 2097 LVTVTATDNG 2106
Score = 53.6 bits (123), Expect = 4e-05
Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 20/187 (10%)
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN K FS++S GS+ + L LD E + + ++ N+ V + +
Sbjct: 1668 GNAPK-FSINSTTGSISV---LPLDREASQEHLLIIILTDGGSRND-----SCTVRVTVA 1718
Query: 298 DLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSID 355
D NDN P+ + + + I E+ G + + A+D D G+NG+F+++ L+D G+ +
Sbjct: 1719 DQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLV 1778
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLE 415
P +G L +R + L K+ + + V G + + R E APLE
Sbjct: 1779 PETGDLVLRRLSSLQ-------SWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLE 1831
Query: 416 --KTTYV 420
K TY+
Sbjct: 1832 FLKQTYL 1838
Score = 52.4 bits (120), Expect = 9e-05
Identities = 80/336 (23%), Positives = 143/336 (42%), Gaps = 33/336 (9%)
Query: 569 DIPDF-MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAVEER 625
++P F M P V N+ +G+ V + D + Y L+ P F +++
Sbjct: 1923 NVPSFPMSKPRR--VPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQF 1980
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
+G I + L P + A + + TN T+ V D+ND K + +
Sbjct: 1981 TGTIHLTAPLDFEVLPEHTLTIKAT--DGSFDTFTNLTIFVSDINDNAPTFSKPLYQTTV 2038
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
+ A + GQ F + + + G + + + +A E G +F +
Sbjct: 2039 -----SPATFSPGQPF-AKIEAHDLDARGALTYSLGQGSSSIFRVA-PESGALFMKVLPP 2091
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYI-EDENDNPPVFEHATYEGFIMENSKIGT 804
+R Y +TV A N GV S + V++ I E E + P FE A + +MENSKIG
Sbjct: 2092 AGER--YLVTVTATDN-GVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGL 2148
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKL 863
+I + ++ E F Y + E ++F +D+ + F+ +DRE++ ++
Sbjct: 2149 QI---GNLSGEESRE-----FHYRIQDPEASKIFSIDKFGRL--FVAGPIDREQRATHEF 2198
Query: 864 SLVARDTGGLSS---EAELIIMIGDENDNKPEFNQI 896
V D ++S + + +++ DENDN P F +
Sbjct: 2199 Q-VEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSV 2233
Score = 49.6 bits (113), Expect = 6e-04
Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 17/194 (8%)
Query: 718 FLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
F++ + + + + E G I T LD EKR + + + K SG I + +
Sbjct: 57 FVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAV----KVEESGETI-DILVE 111
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKE 835
++DENDN P F + I E +++GT + + TD D + + + G
Sbjct: 112 VDDENDNAPSFADQVVKLEISEFAQLGTSFALPTV---TDGDGPKFDVHRFVILQGNVNN 168
Query: 836 MF-----DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAEL--IIMIGDEND 888
+F V+E + LDRE + Y+L + A+D G + +L I I D ND
Sbjct: 169 VFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDAND 228
Query: 889 NKPEFNQIEENSKV 902
N P F++ + V
Sbjct: 229 NAPVFSRSRYTASV 242
Score = 49.2 bits (112), Expect = 9e-04
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 11/149 (7%)
Query: 987 EVKRYFVINERHGHVIVARSLPPES----EFRLNISALDGGNLNDNISVRVFVKDVNDHF 1042
E + F I ++ G + VA + E EF++ I + V V D ND+
Sbjct: 2169 EASKIFSI-DKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNL 2227
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF-EISPLTGV 1101
PVF Y +++++ + +G++ A+D D G+N ++Y I S DL ++P TG
Sbjct: 2228 PVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRIL-SGNDLNIVTLNPDTGS 2286
Query: 1102 LSVN----GELDRETEDKYILTVVARDNG 1126
+ +N +LD + + V ARD+G
Sbjct: 2287 IQLNEWNDAQLDEFPNATWQILVEARDHG 2315
Score = 47.6 bits (108), Expect = 0.003
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Query: 992 FVINERHGHV-IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFP-VFKKTW 1049
F IN G + ++ E L I DGG+ ND+ +VRV V D ND+ P + T
Sbjct: 1673 FSINSTTGSISVLPLDREASQEHLLIIILTDGGSRNDSCTVRVTVADQNDNKPQLDASTP 1732
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
+ E+ VL + A+D D GQN ++ + D+ ++ P TG L
Sbjct: 1733 SELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELL-EDSSGSLDLVPETGDL 1784
Score = 47.2 bits (107), Expect = 0.003
Identities = 105/413 (25%), Positives = 163/413 (39%), Gaps = 73/413 (17%)
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT-YEGFIMENSK 801
PLDRE + + +I + G + + +VT+ D+NDN P + +T E I E+S+
Sbjct: 1686 PLDREASQEHLLIIILT-DGGSRNDSCTVRVTV--ADQNDNKPQLDASTPSELEIAESSR 1742
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
+G + +A+D D G N F + L + D+ TG + S + KI
Sbjct: 1743 VGDVLHR---FRASDMDIGQNGKFSFELLEDSSGSLDLVPETGDLVLRRLSSLQSWKI-- 1797
Query: 862 KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
KL +V GL E L I N N Q E + + ++T L+ TI E
Sbjct: 1798 KLRVVDHGVPGLYVEKNLEI----SNRNP----QTEAKAPLEFLKQTYLS-----TIDEG 1844
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
P+ +F L PE + +I++ N +DS + +SE I +
Sbjct: 1845 LPRGQFIAK--------LQPELAGLTYSIVEGN---IDSA------FSVDSEGVIRTN-- 1885
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
LE+ R I ER+ ++ + R+++ NLNDN+
Sbjct: 1886 ----LELDR--EILERYSLKVIGTGSGQQIGTRVDVRV---NNLNDNV----------PS 1926
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPL 1098
FP+ K N+ Y + V A D D A L YF+ T F I
Sbjct: 1927 FPMSKPRRVPENLRVGSY----VATVGAKDVD--NLAPLRYFLVSDSSGQTPTHFNIDQF 1980
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TG + + LD E ++ LT+ A D D+NDN+P F
Sbjct: 1981 TGTIHLTAPLDFEVLPEHTLTIKATDG----SFDTFTNLTIFVSDINDNAPTF 2029
Score = 44.8 bits (101), Expect = 0.018
Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 9/162 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D + Y + +G++ F +D G+++ ++ +D + ++ + + A
Sbjct: 966 ARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYTKRSIDREVISHVD-----ISIVAE 1018
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P +++ A I +LD+NDN P + I + P ++ ++A D D+G NG
Sbjct: 1019 DKGVPPRSSTASARISVLDVNDNPPSC-LSITPIVVPAGSPLSTAIGTIVAMDPDKGLNG 1077
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
Y+ F + +G + +R Q E H L + V
Sbjct: 1078 SVLYRAQLQSSLFVV-KSNGDVYLRRQLNASDERHQRLSVIV 1118
Score = 44.8 bits (101), Expect = 0.018
Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + +++LD NDN P + ++ + + + + T IG + A+DPD G NG VLY Q
Sbjct: 1027 STASARISVLDVNDNPPSCL--SITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQ 1084
Query: 501 RTSNLTI 507
S+L +
Sbjct: 1085 LQSSLFV 1091
Score = 43.6 bits (98), Expect = 0.043
Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 13/182 (7%)
Query: 218 IHAIDQDLGVGATLRYELISG-----NDRKLFSLDSVNGSLFLEK---ELDLDAEHNLQA 269
+H ++ D VG L+ S ND L+SL G L ++ EL L + ++
Sbjct: 2348 VHVLE-DTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWES 2406
Query: 270 NTFV-LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ + + S N ++ +E +D + P F Y + I + P G SV Q+
Sbjct: 2407 EPIISMYLSVSDGNGRSAVVPLKIVVEPVD--EFAPVFTKSSYTLQIPISTPAGESVGQM 2464
Query: 329 MATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKETN 387
A D+D G +G Y + D + I+ +G + ++ V R + + Y+ T
Sbjct: 2465 QAIDEDGGVHGVVKYSISDRQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTK 2524
Query: 388 PS 389
S
Sbjct: 2525 QS 2526
Score = 40.7 bits (91), Expect = 0.30
Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Query: 994 INERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
I+ + G + + L ESE + +S DG + + +++ V+ V++ PVF K+ Y
Sbjct: 2389 IDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAVVPLKIVVEPVDEFAPVFTKSSYT 2448
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL-DR 1110
+ + +G++ A D D G + + Y I SD +I TG++ + L R
Sbjct: 2449 LQIPISTPAGESVGQMQAIDEDGGVHGVVKYSI--SDRQSTVKIEEHTGIIRLQKPLVSR 2506
Query: 1111 ETEDKYILTVVA 1122
+TVVA
Sbjct: 2507 RNLTIEQITVVA 2518
Score = 40.3 bits (90), Expect = 0.40
Identities = 52/189 (27%), Positives = 77/189 (40%), Gaps = 23/189 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P T + K+ A D DS NGQI Y + YF I+E+ G+V
Sbjct: 953 ENSPPKTIVGKVVARDKDSLENGQIVYRITNG---------------SEYFGIDEKLGNV 997
Query: 1002 IVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
RS+ E S ++I A D G + S R+ V DVND+ P + V
Sbjct: 998 YTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDN-PPSCLSITPIVVPAG 1056
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+G + A D D G N ++ Y Q + + G + + +L+ E
Sbjct: 1057 SPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSS---LFVVKSNGDVYLRRQLNASDERHQR 1113
Query: 1118 LTVVARDNG 1126
L+V+ D G
Sbjct: 1114 LSVIVSDQG 1122
Score = 39.5 bits (88), Expect = 0.69
Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F ++ TG + + LDRE + L ++ D G + + + + D+NDNKP+ +
Sbjct: 1673 FSINSTTGSISVL--PLDREASQEHLLIIILTDGGSRNDSCTVRVTVADQNDNKPQLD-A 1729
Query: 897 EENSKVRIHRETKLNGTA---GFTIIEVKPKNKFALDV--DQLGPLFLIPE 942
S++ I +++ + +++ KF+ ++ D G L L+PE
Sbjct: 1730 STPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLVPE 1780
Score = 37.9 bits (84), Expect = 2.1
Identities = 70/344 (20%), Positives = 144/344 (41%), Gaps = 29/344 (8%)
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVPFAVEERS 626
++P F Y + ++ G +GQI +D + E VSY +L G + + + +
Sbjct: 2226 NLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNI-VTLNPDT 2284
Query: 627 GVITVVDDLSRYNRPMYD-FEAVALQ---ENANLSIVTNATVHVVDVNDERGVLLKGAHS 682
G I L+ +N D F Q E + A V V V+ + A
Sbjct: 2285 GSI----QLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPF 2340
Query: 683 PII----FHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
++ HV E+ S G + +I +N + +G + L +Q + D+ + G
Sbjct: 2341 FVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGL--LYSLKEHQGKLGIDV---KTGE 2395
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ + LD E + M + G + + + I +E ++ PVF ++Y I
Sbjct: 2396 LTLKTHLDWESEPIISMYLSVSDGNG---RSAVVPLKIVVEPVDEFAPVFTKSSYTLQIP 2452
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
++ G + ++A D D G + + Y++ + + ++E+TG+++ + R
Sbjct: 2453 ISTPAGESVGQ---MQAIDEDGGVHGVVKYSI-SDRQSTVKIEEHTGIIRLQKPLVSRRN 2508
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
+ ++++VA + S+ + + IG D +P ++ +SK
Sbjct: 2509 LTIEQITVVAYSSPTKQSKTTVYLEIG-PFDVQPSLPKLLLHSK 2551
Score = 37.5 bits (83), Expect = 2.8
Identities = 48/194 (24%), Positives = 79/194 (40%), Gaps = 16/194 (8%)
Query: 178 HKPVLLLRKVL-DYDAGDKEFQLVIMASGKRIHKE-ILFPEPIHAIDQDLG------VGA 229
H+P L VL D + K QL ++ASG+ +KE + ++I +G
Sbjct: 1202 HRPPYSLVIVLSDKNDRQKSIQLRVLASGEAANKEETIRISDSNSIGTKIGRLGEKSADG 1261
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+ Y S L LD G L+L L HN F + + + +
Sbjct: 1262 SFFYRFSSEESCPL-ELDQTGGLLYLADGLRRGDTHNFSC--FFEKFNTTDGS----AEE 1314
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
RV++E+ + P F+ ++I E+ P G + V AT D + +Y+
Sbjct: 1315 MRVDLEISRTKSDKPRFDTGHLRVNIREDTPTGSIITTVNATVSDDSAS-PISYRFPLLI 1373
Query: 350 GAFSIDPRSGWLTV 363
FSID +G +T+
Sbjct: 1374 DNFSIDQFTGDITL 1387
Score = 36.3 bits (80), Expect = 6.5
Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A L Y ++ GN FS+DS + L+LD E + L+V + + T
Sbjct: 1859 AGLTYSIVEGNIDSAFSVDSEG---VIRTNLELDREI---LERYSLKVIGTGSGQQIGT- 1911
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
RV++ + +LNDN+P F + + ENL G V V A D D
Sbjct: 1912 --RVDVRVNNLNDNVPSFPMSKPR-RVPENLRVGSYVATVGAKDVD 1954
>UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 479
Score = 111 bits (267), Expect = 1e-22
Identities = 124/445 (27%), Positives = 198/445 (44%), Gaps = 42/445 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSN------------AKVGTVIGKVKAVDPDLGQN 492
V + ++D NDNNP+F S LYE ++ N A VG I ++ D D +N
Sbjct: 45 VVIDVVDTNDNNPIFELS-LYETTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAEN 103
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRY 550
+ +L+ S S F ++ N+G +S+A E + L V A D P +
Sbjct: 104 SQL--NLRVVSG-DPNSTFFLS-NSGEISIARKLDYERLQMYNLTVVAWDS-GKPVLQSL 158
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQND-VSY 608
A V I + R N+P F YE WV N+ G V Q++ DA ++QN + Y
Sbjct: 159 KPANVVIRI-RDDNDNQPV---FSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVY 214
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVV 667
++ + F V E +G I + + L Y F +A S T+ V V+
Sbjct: 215 SMVRNNSK---FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVM 271
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
DVND + + + A Q T+ S + ++IA+ +
Sbjct: 272 DVNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGS-----NAKIEYIIASG-NTN 325
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I G + K +D E R +Y +T++A + G I V + IEDENDNPPVF
Sbjct: 326 NSFDIDNHGFVTVNKAIDFETRKIYNLTIMAR-DCGDPVLTSIVSVVLLIEDENDNPPVF 384
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVV 846
+ Y + EN I +I + A+D+D G N+ Y+ G + F ++ NTG++
Sbjct: 385 DLPYYFVRMYENVSIRADIIR---VHASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMI 441
Query: 847 KFIGDSLDREKKIMYKLSLVARDTG 871
+ +D E+K +Y+ S++A D G
Sbjct: 442 -YTRHEIDFEEKRVYEFSVIASDQG 465
Score = 95.1 bits (226), Expect = 1e-17
Identities = 84/298 (28%), Positives = 130/298 (43%), Gaps = 22/298 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATV--HVVDVNDERGVL 676
FAV + GVIT+ L ++ A + +L T A V VVD ND +
Sbjct: 1 FAVNDY-GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIF 59
Query: 677 LKGAHSPIIFHVKENSAG--------AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ I ++ +AG A +GQ S + L D
Sbjct: 60 ELSLYETTI--LENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNS 117
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVF 787
++ G I + LD E+ +Y +TV+A + K V+ V I I D+NDN PVF
Sbjct: 118 TFFLSNSGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVF 177
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
YE +++EN G + +KA DAD N +Y++ F V+E TG +
Sbjct: 178 SRDLYEAWVLENITAGQFVVQ---VKAKDADYQQNGRLVYSMV-RNNSKFRVNETTGEI- 232
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
++ +SLD E+ Y ++A D+G SS + +++ D NDN P F++ S VR
Sbjct: 233 YLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVR 290
Score = 90.2 bits (214), Expect = 4e-16
Identities = 84/316 (26%), Positives = 145/316 (45%), Gaps = 25/316 (7%)
Query: 588 IGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDF 645
+G ++ ++ V ND E + ++ ++ G F SG I++ L MY+
Sbjct: 86 VGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFL--SNSGEISIARKLDYERLQMYNL 143
Query: 646 EAVALQENANL--SIV-TNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
VA + S+ N + + D ND + V + + + ++ +AG + Q+
Sbjct: 144 TVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEAWV--LENITAGQFVVQVKA 201
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNK 762
+ Y V ++ N + G I+ + LD E+ Y +IA +
Sbjct: 202 KDAD--YQQNGRLVYSMVRNNSKFRVN---ETTGEIYLSESLDFEETKEYVFGIIAS-DS 255
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE-IKMDNIIKATDADEGT 821
GV + V + + D NDN P F+ Y+ + ENS +GT IK ++A D D G+
Sbjct: 256 GVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTAIK----VQAIDTDTGS 311
Query: 822 NALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAE 878
NA Y + G FD+D N G V + ++D E + +Y L+++ARD G L+S
Sbjct: 312 NAKIEYIIASGNTNNSFDID-NHGFVT-VNKAIDFETRKIYNLTIMARDCGDPVLTSIVS 369
Query: 879 LIIMIGDENDNKPEFN 894
++++I DENDN P F+
Sbjct: 370 VVLLIEDENDNPPVFD 385
Score = 89.0 bits (211), Expect = 9e-16
Identities = 134/524 (25%), Positives = 219/524 (41%), Gaps = 110/524 (20%)
Query: 852 SLDREKKIMYKLSLVARDTGGLSSE----AELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
SLD E+ + L++ A D G S E A ++I + D NDN P F ++ ++
Sbjct: 14 SLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIF-------ELSLYET 66
Query: 908 TKL-NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
T L N TAG ++ ++ E P+G TI++L D D+ N Q+
Sbjct: 67 TILENTTAGSSV--------------------MVSEYAPVGQTILRLTVSDNDTAENSQL 106
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN 1024
N V +S D +F+ N G + +AR L E + L + A D G
Sbjct: 107 ----NLRV------VSGDPNST--FFLSNS--GEISIARKLDYERLQMYNLTVVAWDSGK 152
Query: 1025 --LND--NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
L +V + ++D ND+ PVF + Y V E + + +V A DAD+ QN L
Sbjct: 153 PVLQSLKPANVVIRIRDDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRL 212
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y + +++ F ++ TG + ++ LD E +Y+ ++A D+G
Sbjct: 213 VYSMVRNNS--KFRVNETTGEIYLSESLDFEETKEYVFGIIASDSG-VEPKSSSTSVRVI 269
Query: 1141 XXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF 1200
DVNDN P F F +YK+T+ EN+P+GTT KV
Sbjct: 270 VMDVNDNVPTFDRF--------------------------LYKSTVRENSPVGTTAIKVQ 303
Query: 1201 ANDTD---------FIGNGN----------GLILYSLP---QRKNQQNLGLPSLSSTAIL 1238
A DTD I +GN G + + + + NL + + +
Sbjct: 304 AIDTDTGSNAKIEYIIASGNTNNSFDIDNHGFVTVNKAIDFETRKIYNLTIMARDCGDPV 363
Query: 1239 MVTVADVP--DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYYI 1294
+ ++ V E E + PVF YY + + ENV+ +++ ++ ++ F ++RY
Sbjct: 364 LTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGFNSEIRY-- 421
Query: 1295 LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ + + F I+ G +Y D E K YE V A Q
Sbjct: 422 -SFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQ 464
Score = 82.2 bits (194), Expect = 1e-13
Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 18/191 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P+GTT IK+ A+D D+G N +I Y I S + ++ ++ + HG
Sbjct: 289 VRENSPVGTTAIKVQAIDTDTGSNAKIEY-------IIASGNTNNSFDI-------DNHG 334
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V V +++ E+ + L I A D G+ L +SV + ++D ND+ PVF +Y +
Sbjct: 335 FVTVNKAIDFETRKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMY 394
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E R + +V A+D+D G N+ + Y PF I+ TG++ E+D E +
Sbjct: 395 ENVSIRADIIRVHASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFEEKRV 454
Query: 1116 YILTVVARDNG 1126
Y +V+A D G
Sbjct: 455 YEFSVIASDQG 465
Score = 77.8 bits (183), Expect = 2e-12
Identities = 83/327 (25%), Positives = 140/327 (42%), Gaps = 27/327 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
Q + NV + + D NDN PVF +LYE + N G + +VKA D D QNG ++Y
Sbjct: 156 QSLKPANVVIRIRDDNDNQPVF-SRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVY 214
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAES-PILEGRHALF-VEASDQPANPSERRYSLAVV 555
+ R + S F++N TG + ++ES E + +F + ASD P S+ V+
Sbjct: 215 SMVRNN-----SKFRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVI 269
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG 613
++V ++P F Y+ V N +GT+ +++ D + Y + G
Sbjct: 270 VMDV-------NDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYIIASG 322
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDE 672
F ++ G +TV + R +Y+ +A + L+ + + + + D ND
Sbjct: 323 NTNN-SFDIDNH-GFVTVNKAIDFETRKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDN 380
Query: 673 RGVLLKGAHSPIIF-HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
V P F + EN + A I + S +R+ V
Sbjct: 381 PPVF----DLPYYFVRMYENVSIRA--DIIRVHASDSDSGFNSEIRYSFPVGFVVKPFAI 434
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIA 758
A G I+T+ +D E++ VY +VIA
Sbjct: 435 NANTGMIYTRHEIDFEEKRVYEFSVIA 461
Score = 69.3 bits (162), Expect = 8e-10
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 12/153 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D G A + Y + SGN F +D+ +G + + K +D + + L +
Sbjct: 302 VQAIDTDTGSNAKIEYIIASGNTNNSFDIDN-HGFVTVNKAIDFETR-----KIYNLTIM 355
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P+ T+ V + + D NDN P F++ +Y + + EN+ +++V A+D D G
Sbjct: 356 ARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGF 415
Query: 338 NGEFTYQLDDPKG----AFSIDPRSGWLTVRNQ 366
N E Y P G F+I+ +G + R++
Sbjct: 416 NSEIRYSF--PVGFVVKPFAINANTGMIYTRHE 446
Score = 68.9 bits (161), Expect = 1e-09
Identities = 45/180 (25%), Positives = 83/180 (46%), Gaps = 12/180 (6%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
F + A D D L Y ++ N + F ++ G ++L + LD + + +V
Sbjct: 195 FVVQVKAKDADYQQNGRLVYSMVRNNSK--FRVNETTGEIYLSESLDFE-----ETKEYV 247
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ AS K++ V + ++D+NDN+P F+ Y ++ EN P G + ++V A D
Sbjct: 248 FGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDT 307
Query: 334 DQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
D G N + Y + + +F ID G++TV +D E + + A++ V+
Sbjct: 308 DTGSNAKIEYIIASGNTNNSFDID-NHGFVTVNK--AIDFETRKIYNLTIMARDCGDPVL 364
Score = 62.5 bits (145), Expect = 9e-08
Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 11/238 (4%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D + L ++SG+ F L + +G + + ++LD + + + L V A
Sbjct: 97 DNDTAENSQLNLRVVSGDPNSTFFLSN-SGEISIARKLDYE-----RLQMYNLTVVAWDS 150
Query: 282 NNPLKTA--QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P+ + A V I + D NDN P F D Y ++EN+ G V+QV A D D +NG
Sbjct: 151 GKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNG 210
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQR 399
Y + F ++ +G + + LD E + A ++ + +
Sbjct: 211 RLVYSMVRNNSKFRVNETTGEIYLSES--LDFEETKEYVFGIIASDSGVEPKSSSTSVRV 268
Query: 400 IAKWRRQPLET-NAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
I + T + L K+T VGT ++ D S +E + N NN
Sbjct: 269 IVMDVNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYIIASGNTNN 326
Score = 60.9 bits (141), Expect = 3e-07
Identities = 64/238 (26%), Positives = 111/238 (46%), Gaps = 21/238 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E S +V V ++D NDN P F LY+ +++ N+ VGT KV+A+D D G N +
Sbjct: 258 EPKSSSTSVRVIVMDVNDNVPTF-DRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIE 316
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAV 554
Y + S T S F I+ N G V+V ++ E R + L + A D +P V
Sbjct: 317 YII--ASGNTNNS-FDID-NHGFVTVNKAIDFETRKIYNLTIMARD-CGDPVLTSIVSVV 371
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
+ IE ++ D P PY F + NV I + ++ +D+ +++ Y
Sbjct: 372 LLIE-------DENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGFNSEIRYSFP 424
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
G+ PFA+ +G+I ++ + +Y+F +A + + ++ + + VDV
Sbjct: 425 VGFVV-KPFAINANTGMIYTRHEIDFEEKRVYEFSVIA--SDQGIPVLRDVAIVRVDV 479
Score = 54.4 bits (125), Expect = 2e-05
Identities = 104/423 (24%), Positives = 178/423 (42%), Gaps = 73/423 (17%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVK----DVNDHFPVF 1045
F +N+ +G + + +SL E + F L I+A D G + + R V D ND+ P+F
Sbjct: 1 FAVND-YGVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIF 59
Query: 1046 KKTWYNFNVEE----------AQY--TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
+ + Y + E ++Y + + ++ +D D +N+ L + D + F
Sbjct: 60 ELSLYETTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTF 119
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKFY 1152
+S +G +S+ +LD E Y LTVVA D+G D NDN P F
Sbjct: 120 FLSN-SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVF- 177
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN--- 1209
+ D W + ++ F V+ + A ++N G V + N++ F N
Sbjct: 178 SRDLYEAW---VLENITAGQF--VVQVKAKDADYQQN---GRLVYSMVRNNSKFRVNETT 229
Query: 1210 GNGLILYSLPQRKNQQ--------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRY 1261
G + SL + ++ + G+ SS+ + V V DV D V P F
Sbjct: 230 GEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNV-----PTFDRFL 284
Query: 1262 YELEIEENVNAPVELVSLNL----TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYL 1317
Y+ + E N+PV ++ + T+ N K+ Y I + N + +F ID +G + +
Sbjct: 285 YKSTVRE--NSPVGTTAIKVQAIDTDTGSNAKIEYIIASGNTNN---SFDID-NHGFVTV 338
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
++ D E + Y + + A + VL + V VV+ I+D NDN
Sbjct: 339 NKAIDFETRKIYNLTIMAR-------------DCGDPVLTSI----VSVVLLIEDENDNP 381
Query: 1378 PKF 1380
P F
Sbjct: 382 PVF 384
Score = 50.0 bits (114), Expect = 5e-04
Identities = 58/219 (26%), Positives = 89/219 (40%), Gaps = 23/219 (10%)
Query: 60 DFDEGDD----LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK 115
DF+E + ++ +G+ S+ SV V + DVNDNVP F Y TV E +P G
Sbjct: 239 DFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTT 298
Query: 116 AFIF--LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPN--TPNSDVHYS-------IV 164
A + G + I + G T +FD D T N + + +
Sbjct: 299 AIKVQAIDTDTGSNAKIEYIIASGNT----NNSFDIDNHGFVTVNKAIDFETRKIYNLTI 354
Query: 165 SGNDDGHFALESSHKPVLLLRKVLDY-DAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQ 223
D G L S VLL+ D D + V M I +I+ +HA D
Sbjct: 355 MARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADII---RVHASDS 411
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD 262
D G + +RY G K F++++ G ++ E+D +
Sbjct: 412 DSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFE 450
Score = 48.4 bits (110), Expect = 0.002
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 22/160 (13%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNP-LKTA-QARVEIELLDLNDNLPEFEVDFYNISIVEN 318
LD+E N TF L + A P L+TA +A V I+++D NDN P FE+ Y +I+EN
Sbjct: 15 LDSERN---TTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYETTILEN 71
Query: 319 ------------LPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVR 364
P G ++L++ +D D EN + ++ DP F + SG +++
Sbjct: 72 TTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFLS-NSGEISIA 130
Query: 365 NQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWR 404
+ LD E + V A ++ V+ + + + + R
Sbjct: 131 RK--LDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIR 168
Score = 44.0 bits (99), Expect = 0.032
Identities = 36/108 (33%), Positives = 46/108 (42%), Gaps = 6/108 (5%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L S V+V + + D NDN PVF Y M N + I +V A D D G N +
Sbjct: 361 DPVLTSIVSVVLLIEDENDNPPVF-DLPYYFVRMYENVSIRADIIRVHASDSDSGFNSEI 419
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQ 541
Y + PF IN NTG + E + + V ASDQ
Sbjct: 420 RYSFPVG---FVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQ 464
Score = 41.1 bits (92), Expect = 0.23
Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 20/128 (15%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V + + D NDN PIF + Y T+ E T G + AP+G ++ + LTV
Sbjct: 45 VVIDVVDTNDNNPIFELSLYETTILENTTAGSSVMVSEYAPVGQTI-LRLTV-------- 95
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIM 202
D NS ++ +VSG+ + F L +S + + + RK LDY+ + + L ++
Sbjct: 96 ------SDNDTAENSQLNLRVVSGDPNSTFFLSNSGE-ISIARK-LDYER-LQMYNLTVV 146
Query: 203 A--SGKRI 208
A SGK +
Sbjct: 147 AWDSGKPV 154
Score = 35.9 bits (79), Expect = 8.6
Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 20/160 (12%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G+PSL TA + V DV D + + P+F YE I EN A ++ +
Sbjct: 33 GMPSLE-TATRAIVVIDVVDTND--NNPIFELSLYETTILENTTAGSSVMVSEYAPVGQT 89
Query: 1288 FKMRYYILNENDT----DIRRTFVIDPRNGTLYLVRSPDREV--KDTYEVIVRAERQKYS 1341
+R + ++NDT + V N T +L S + + K YE + Q Y+
Sbjct: 90 I-LRLTV-SDNDTAENSQLNLRVVSGDPNSTFFLSNSGEISIARKLDYERL-----QMYN 142
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
L + + + VL+ + VV+RI+D NDN P F+
Sbjct: 143 --LTVVAWDSGKPVLQSLKP--ANVVIRIRDDNDNQPVFS 178
>UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 943
Score = 111 bits (267), Expect = 1e-22
Identities = 161/627 (25%), Positives = 254/627 (40%), Gaps = 86/627 (13%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
P F+ PY V N G +V ++ DA ++ + G F V G +
Sbjct: 326 PKFVNLPYSGTVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGAAG-KFVVSSE-GYVV 383
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK- 689
V ++ R + Y+F+ +A+L NA V + D G+ P+ +K
Sbjct: 384 VSGNIDRETQDTYEFKVSV--SDADLG--PNADVRFSFIPDSSGLDKLFTIDPVSGDIKT 439
Query: 690 ------ENSAGAAIGQIFHTNMSSIYGNGT--GNVRFLIANQQDVT---DDIAI--AEDG 736
E +G S G N RF+ + T D+IA G
Sbjct: 440 LATFDREERVSYGLGIRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIANKRGNSG 499
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ T LDRE VY + V A G + + T+ ++D NDN PVF EG+
Sbjct: 500 LVKTSSSLDRETTPVYTLVVRATDGGGKEVTSSL---TVILDDVNDNAPVFSRP--EGYT 554
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDR 855
E + G + + + +ATD D G NA +Y+L F +D TGV+K SLDR
Sbjct: 555 FEVQEGGVGLSVGTV-QATDRDSGINAATLYSLKSVADYSKFIIDSKTGVIK-TSFSLDR 612
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR------- 906
E + + ++ARDTG LS+E +I+ + D ND++P F+Q + + V+ R
Sbjct: 613 ETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKRASHVILT 672
Query: 907 ------ETKLNGTAGFTIIEVKPKNKFALD-----VDQLGPLFLIPENIPIGTTIIKLNA 955
+ +N + I N F LD + GP L E T ++ ++
Sbjct: 673 LTATDSDRGINSALHYMIDSGNFGNSFTLDALTGSLSTTGP--LDREVRAEYTLLVFVSD 730
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI---NERHGHVIV---ARSLPP 1009
L ++ L +R V+I ++ +Y + + G I+ AR +
Sbjct: 731 LQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDS 790
Query: 1010 ESEFRLNISALDGGNLN----DNISVRVFVKDVNDHFPVFKKTWYNFNV----------- 1054
L+ S + G +L D+ S RV+VK D P + Y V
Sbjct: 791 GISQNLHYSIVSGNSLGRFFIDSSSARVYVKSPLDRDPPRNEGAYTLEVTITISDVNDSP 850
Query: 1055 ---EEAQYTRRV-----LGKV----DATDADFGQNANLTYFIQPSDTDLP--FEISPLTG 1100
+A Y+ R+ LG V D D G N ++Y I +++ P F ++P +G
Sbjct: 851 PEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSG 910
Query: 1101 VLSVNGELDRETEDK-YILTVVARDNG 1126
LSV+ E D +T K Y L + A D G
Sbjct: 911 ALSVSTEFDFDTGRKSYSLVLTATDKG 937
Score = 91.9 bits (218), Expect = 1e-16
Identities = 140/590 (23%), Positives = 240/590 (40%), Gaps = 82/590 (13%)
Query: 793 EGFIMENSKIGTEIK--MDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVK 847
EG+++ + I E + + + +DAD G NA ++ + ++F +D +G +K
Sbjct: 379 EGYVVVSGNIDRETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTIDPVSGDIK 438
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEN-----DNKPE------FNQI 896
+ + DRE+++ Y L + D S + + I ++ DN+ N+
Sbjct: 439 TLA-TFDREERVSYGLGIRVIDQP--SGQQGRYVYIANKRFIRSRDNQTTRKGDNIANKR 495
Query: 897 EENSKVRIHRETKLNGTAGFTII---------EVKPKNKFALD-VDQLGPLFLIPENIP- 945
+ V+ T +T++ EV LD V+ P+F PE
Sbjct: 496 GNSGLVKTSSSLDRETTPVYTLVVRATDGGGKEVTSSLTVILDDVNDNAPVFSRPEGYTF 555
Query: 946 ------IGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+G ++ + A D DSG+N Y S AD + F+I+ + G
Sbjct: 556 EVQEGGVGLSVGTVQATDRDSGINAATLYSLKSV---------ADYSK----FIIDSKTG 602
Query: 1000 HVIVARSLPPESEFRLNISAL--DGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + SL E++ +LNI + D G+ L+ + + V V D+NDH P F + Y+ V+
Sbjct: 603 VIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQ 662
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E + + +L + ATD+D G N+ L Y I + F + LTG LS G LDRE +
Sbjct: 663 EKRASHVIL-TLTATDSDRGINSALHYMIDSGNFGNSFTLDALTGSLSTTGPLDREVRAE 721
Query: 1116 YILTVVARD-NGXXXX---XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
Y L V D G D+NDNSP F L +
Sbjct: 722 YTLLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSL--------TIPED 773
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGLILYSLP-QRKNQQNLG 1228
+I V I+ + V N FI + + + P R +N G
Sbjct: 774 TAPGTGIIQVQARDIDSGISQNLHYSIVSGNSLGRFFIDSSSARVYVKSPLDRDPPRNEG 833
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YE 1286
+L T +T++DV D P F Y + I EN+ ++ + +
Sbjct: 834 AYTLEVT----ITISDVND-----SPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGT 884
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV-KDTYEVIVRA 1335
N ++ Y+I + N R F ++P +G L + D + + +Y +++ A
Sbjct: 885 NGQISYHISSGNSETPPR-FSVNPSSGALSVSTEFDFDTGRKSYSLVLTA 933
Score = 85.0 bits (201), Expect = 1e-14
Identities = 89/320 (27%), Positives = 142/320 (44%), Gaps = 48/320 (15%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V V IEDVNDN P+F++TPY ++V E T G T F
Sbjct: 120 VRVQIEDVNDNTPVFINTPYSISVKENT-------------------------LGTTGFA 154
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK--VLDYDAGDKEFQLV 200
++A D D+ N+ + YSI GN+ F + + + + VLDY+ K F L
Sbjct: 155 -VKATDADQGQ--NALIKYSITGGNEANMFKIGAYEGTISVFPDSGVLDYEKY-KSFNLT 210
Query: 201 IMAS------GKRIHKEILFPEPIHAIDQDLGVGATLRYEL-ISGNDRKLFSLDSV---N 250
+ AS G R +F + +D V + Y ++ + K F + +V +
Sbjct: 211 VSASDLGGVNGSRTAVTSVFIR-VEDVDDLPAVFSPDYYTAKVAESSTKGFYVTTVTARD 269
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQL---NNPLKTAQARVEIELLDLNDNLPEFE 307
G L L K + + + + + +S + + K A V+I + D+NDN P+F
Sbjct: 270 GDLSLNKPVSYFIDQGITTSPQHYEPVSSSIKAISTIHKAVFATVQITITDINDNAPKFV 329
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQT 367
Y+ ++ EN P G +VL+V A D D G+N +FTY L G F + G++ V
Sbjct: 330 NLPYSGTVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGAAGKFVVS-SEGYVVVSGN- 387
Query: 368 VLDREAHSSLRMKVYAKETN 387
+DRE + KV + +
Sbjct: 388 -IDRETQDTYEFKVSVSDAD 406
Score = 80.6 bits (190), Expect = 3e-13
Identities = 111/432 (25%), Positives = 176/432 (40%), Gaps = 49/432 (11%)
Query: 482 VKAVDPDLGQNGMVLYD-----LQRTSNLTITSPFKI---NPNTGTVSVAESPILEGR-- 531
++ +D GQ G +Y ++ N T I N+G V + S E
Sbjct: 455 IRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIANKRGNSGLVKTSSSLDRETTPV 514
Query: 532 HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS 591
+ L V A+D E SL V+ +V N P G +E G G+G S
Sbjct: 515 YTLVVRATD--GGGKEVTSSLTVILDDVN----DNAPVFSRPEGYTFEVQEG---GVGLS 565
Query: 592 VGQIRVNDAFEQ-NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL 650
VG ++ D N + L + F ++ ++GVI L R + + +A
Sbjct: 566 VGTVQATDRDSGINAATLYSLKSVADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIAR 625
Query: 651 QENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
+ LS V+V D+ND R + +S V+E A I + T+
Sbjct: 626 DTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVT---VQEKRASHVILTLTATDSD--- 679
Query: 710 GNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS-G 767
G + + + + + + A G++ T PLDRE R Y + V +G S G
Sbjct: 680 -RGINSALHYMIDSGNFGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLG 738
Query: 768 AGIYQ---VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
+ V ++IED NDN PVF + Y I E++ GT I ++A D D G +
Sbjct: 739 IPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQ---VQARDIDSGISQN 795
Query: 825 FMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
Y++ G F +D ++ V ++ LDR+ R+ G + E+ I I
Sbjct: 796 LHYSIVSGNSLGRFFIDSSSARV-YVKSPLDRDPP---------RNEGAYT--LEVTITI 843
Query: 884 GDENDNKPEFNQ 895
D ND+ PEF+Q
Sbjct: 844 SDVNDSPPEFSQ 855
Score = 80.6 bits (190), Expect = 3e-13
Identities = 107/438 (24%), Positives = 170/438 (38%), Gaps = 42/438 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V L D NDN PVF Y F ++ VG +G V+A D D G N LY L+ +
Sbjct: 532 SLTVILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVGTVQATDRDSGINAATLYSLKSVA 590
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ S F I+ TG + + S E + L + + + + ++ + VT
Sbjct: 591 DY---SKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGII-VNVT--- 643
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE 623
P F Y V + + N + ++ G F ++
Sbjct: 644 -DINDHRPAFSQRQYSVTVQEKRASHVILTLTATDSDRGINSALHYMIDSGNFGNSFTLD 702
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLSIVTN----ATVHVVDVNDERGVLL 677
+G ++ L R R Y LQ NA+L I V + D+ND V
Sbjct: 703 ALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFP 762
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ +S I ++ + G I Q+ ++ S + N+ + I + + +
Sbjct: 763 QSQYSLTI--PEDTAPGTGIIQVQARDIDS---GISQNLHYSIVSGNSLGRFFIDSSSAR 817
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++ + PLD RD R GA +VTI I D ND+PP F A Y I
Sbjct: 818 VYVKSPLD---RDPPRN-----------EGAYTLEVTITISDVNDSPPEFSQAMYSVRIP 863
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE---MFDVDENTGVVKFIGD-SL 853
EN +GT + + + D D GTN Y + E F V+ ++G + +
Sbjct: 864 ENITLGTVVLQPSCV---DRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDF 920
Query: 854 DREKKIMYKLSLVARDTG 871
D +K Y L L A D G
Sbjct: 921 DTGRK-SYSLVLTATDKG 937
Score = 77.0 bits (181), Expect = 4e-12
Identities = 81/304 (26%), Positives = 126/304 (41%), Gaps = 21/304 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
S+TV ++DVNDN P+F P T E+ G + + I L
Sbjct: 532 SLTVILDDVNDNAPVF-SRPEGYTF-EVQEGGVGLSVGTVQATDRDSGINAATLYSLKSV 589
Query: 142 KDIRAFDRDKP----------NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
D F D + D V D G L + ++ + + D+
Sbjct: 590 ADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHR 649
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
+ Q + KR IL + A D D G+ + L Y + SGN F+LD++ G
Sbjct: 650 PAFSQRQYSVTVQEKRASHVIL---TLTATDSDRGINSALHYMIDSGNFGNSFTLDALTG 706
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQAS-QLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
SL LD + FV +Q + L PL+ + A V + + D+NDN P F
Sbjct: 707 SLSTTGPLDREVRAEYTLLVFVSDLQGNASLGIPLRDS-AVVNVFIEDMNDNSPVFPQSQ 765
Query: 311 YNISIVENLPNGFSVLQVMATDKDQG--ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
Y+++I E+ G ++QV A D D G +N ++ + G F ID S + V++
Sbjct: 766 YSLTIPEDTAPGTGIIQVQARDIDSGISQNLHYSIVSGNSLGRFFIDSSSARVYVKSP-- 823
Query: 369 LDRE 372
LDR+
Sbjct: 824 LDRD 827
Score = 72.1 bits (169), Expect = 1e-10
Identities = 109/409 (26%), Positives = 170/409 (41%), Gaps = 67/409 (16%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P GT ++ + A+D + N QI Y+ LS + K V E
Sbjct: 38 LPENQPTGTGVLTVRAVDNE---NDQITYQ-----------LSGEDGRFKINSVTGEITS 83
Query: 1000 HVIVARS-LPPESEFRLNISALD----GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+V + R LP + A D G + ++ VRV ++DVND+ PVF T Y+ +V
Sbjct: 84 NVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRVQIEDVNDNTPVFINTPYSISV 143
Query: 1055 EEAQYTRRVLG-KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV---NGELDR 1110
+E T G V ATDAD GQNA + Y I + F+I G +SV +G LD
Sbjct: 144 KE--NTLGTTGFAVKATDADQGQNALIKYSITGGNEANMFKIGAYEGTISVFPDSGVLDY 201
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E + LTV A D G + D+ P ++ D + + E S
Sbjct: 202 EKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDDLPAVFSPD----YYTAKVAESST 257
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLP 1230
F V + + N P+ + FI G + + PQ + +
Sbjct: 258 KGF-YVTTVTARDGDLSLNKPV-----------SYFIDQG----ITTSPQHYEPVSSSIK 301
Query: 1231 SLSST-----AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--- 1282
++S+ A + +T+ D+ D + P F++ Y + E N+P L L +T
Sbjct: 302 AISTIHKAVFATVQITITDIND-----NAPKFVNLPYSGTVPE--NSPTGLTVLRVTAQD 354
Query: 1283 -EHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
+ +N K Y + T FV+ G + + + DRE +DTYE
Sbjct: 355 ADSGDNAKFTYSL-----TGAAGKFVVS-SEGYVVVSGNIDRETQDTYE 397
Score = 72.1 bits (169), Expect = 1e-10
Identities = 51/179 (28%), Positives = 80/179 (44%), Gaps = 22/179 (12%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ L Y ++SGN F +DS + ++++ LD D N A T
Sbjct: 783 VQARDIDSGISQNLHYSIVSGNSLGRFFIDSSSARVYVKSPLDRDPPRNEGAYTL----- 837
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
V I + D+ND+ PEF Y++ I EN+ G VLQ D+D G
Sbjct: 838 -------------EVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGT 884
Query: 338 NGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
NG+ +Y + + FS++P SG L+V + D S + + P++ G
Sbjct: 885 NGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALSG 943
Score = 69.7 bits (163), Expect = 6e-10
Identities = 60/262 (22%), Positives = 114/262 (43%), Gaps = 16/262 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G+ A Y L S D F +DS G ++ LD E Q N ++V
Sbjct: 569 VQATDRDSGINAATLYSLKSVADYSKFIIDSKTG--VIKTSFSLDRETQDQLN---IRVI 623
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P +A+ + + + D+ND+ P F Y++++ E + +L + ATD D+G
Sbjct: 624 ARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKRAS-HVILTLTATDSDRGI 682
Query: 338 NGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV-VGTF 394
N Y +D +F++D +G L+ LDRE + + V+ + + +G
Sbjct: 683 NSALHYMIDSGNFGNSFTLDALTGSLSTTGP--LDREVRAEYTLLVFVSDLQGNASLGIP 740
Query: 395 ADSQRIAKWRRQPLETNAPL---EKTTYVFPDKVGTKTENIEYYDEQLMSFV--NVEVTL 449
+ + + N+P+ + + P+ T I+ + S + N+ ++
Sbjct: 741 LRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDSGISQNLHYSI 800
Query: 450 LDANDNNPVFVPSNLYEFSMKS 471
+ N F+ S+ +KS
Sbjct: 801 VSGNSLGRFFIDSSSARVYVKS 822
Score = 66.5 bits (155), Expect = 5e-09
Identities = 51/155 (32%), Positives = 75/155 (48%), Gaps = 11/155 (7%)
Query: 736 GTIFTQKPLDREK---RDVYRMTVIAEFNKGVISGAGI-YQVTIYIEDENDNPPVFEHAT 791
G I + +DREK ++ IA KG + V + IED NDN PVF +
Sbjct: 79 GEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRVQIEDVNDNTPVFINTP 138
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIG 850
Y + EN+ +GT +KATDAD+G NAL Y++ G + MF + G +
Sbjct: 139 YSISVKENT-LGTT---GFAVKATDADQGQNALIKYSITGGNEANMFKIGAYEGTISVFP 194
Query: 851 DS--LDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
DS LD EK + L++ A D GG++ + +
Sbjct: 195 DSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSV 229
Score = 66.5 bits (155), Expect = 5e-09
Identities = 138/585 (23%), Positives = 226/585 (38%), Gaps = 95/585 (16%)
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE-FNQIEENSKVRIHRETKLNGTAGF 916
K Y ++ ARD G LS + I P+ + + + K + T
Sbjct: 258 KGFYVTTVTARD-GDLSLNKPVSYFIDQGITTSPQHYEPVSSSIKAISTIHKAVFATVQI 316
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
TI ++ +++ G +PEN P G T++++ A D DSG N + Y
Sbjct: 317 TITDINDNAPKFVNLPYSGT---VPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGAA-- 371
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRV- 1033
FV++ G+V+V+ ++ E++ + +S D +L N VR
Sbjct: 372 -------------GKFVVSSE-GYVVVSGNIDRETQDTYEFKVSVSDA-DLGPNADVRFS 416
Query: 1034 FVKDVNDHFPVFK--------KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY--- 1082
F+ D + +F KT F+ EE LG + D GQ Y
Sbjct: 417 FIPDSSGLDKLFTIDPVSGDIKTLATFDREER--VSYGLG-IRVIDQPSGQQGRYVYIAN 473
Query: 1083 --FIQPSDTDLPFEISPL------TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXX 1134
FI+ D + + +G++ + LDRET Y L V A D G
Sbjct: 474 KRFIRSRDNQTTRKGDNIANKRGNSGLVKTSSSLDRETTPVYTLVVRATDGGGKEVTSSL 533
Query: 1135 XXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGT 1194
DVNDN+P F PE + + +AT ++
Sbjct: 534 TVILD---DVNDNAPVF---------SRPEGYTFEVQEGGVGLSVGTVQATDRDSGINAA 581
Query: 1195 TV--AKVFANDTDFI-GNGNGLILYSLP-QRKNQQNL---------GLPSLSSTAILMVT 1241
T+ K A+ + FI + G+I S R+ Q L G P LS+ ++V
Sbjct: 582 TLYSLKSVADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVN 641
Query: 1242 VADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTD 1301
V D+ D +P F R Y + ++E + V +++L T+ + + ++ +
Sbjct: 642 VTDINDH-----RPAFSQRQYSVTVQEKRASHV-ILTLTATDSDRGINSALHYMIDSG-N 694
Query: 1302 IRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTK 1361
+F +D G+L DREV+ Y ++V + + L G+
Sbjct: 695 FGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASL-------------GIPL 741
Query: 1362 YDVKVV-VRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
D VV V I+D+NDNSP F L T TAP G ++Q++
Sbjct: 742 RDSAVVNVFIEDMNDNSPVFPQSQYSL-TIPEDTAP-GTGIIQVQ 784
Score = 64.5 bits (150), Expect = 2e-08
Identities = 109/436 (25%), Positives = 172/436 (39%), Gaps = 56/436 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+E L+ N+P Y + N GT + V+AVD +N + Y L
Sbjct: 14 IEAALIQGQANSPPRFVETQYVGRLPENQPTGTGVLTVRAVD---NENDQITYQLSGEDG 70
Query: 505 LTITSPFKINPNTGTVSV---AESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
FKIN TG ++ + L G + L +A A + Y V + V
Sbjct: 71 R-----FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYR---VDVPVRV 122
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLLHGYEEGVP 619
+ + P F+ PY V N +GT+ ++ DA + QN + Y + G E +
Sbjct: 123 QIEDVNDNTPVFINTPYSISVKENT-LGTTGFAVKATDADQGQNALIKYSITGGNEANM- 180
Query: 620 FAVEERSGVITVVDDLSRYNRPMY-DFE-AVALQE----NANLSIVTNATVHVVDVNDER 673
F + G I+V D + Y F V+ + N + + VT+ + V DV+D
Sbjct: 181 FKIGAYEGTISVFPDSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDD-- 238
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
L SP + K A ++ + T +++ G+ + N Q +T
Sbjct: 239 ---LPAVFSPDYYTAKV--AESSTKGFYVTTVTARDGDLSLNKPVSYFIDQGITTSPQHY 293
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E P+ + I+ +K V + V I I D NDN P F + Y
Sbjct: 294 E--------PVSSS------IKAISTIHKAVFA-----TVQITITDINDNAPKFVNLPYS 334
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
G + ENS G + + A DAD G NA F Y+L G + F V VV + ++
Sbjct: 335 GTVPENSPTGLTVLR---VTAQDADSGDNAKFTYSLTGAAGK-FVVSSEGYVV--VSGNI 388
Query: 854 DREKKIMYKLSLVARD 869
DRE + Y+ + D
Sbjct: 389 DRETQDTYEFKVSVSD 404
Score = 54.8 bits (126), Expect = 2e-05
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 5/102 (4%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ V +T+ D ND+ P F + +Y + N +GTV+ + VD DLG NG + Y + +
Sbjct: 837 LEVTITISDVNDSPPEFSQA-MYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHIS-S 894
Query: 503 SNLTITSPFKINPNTGTVSVA-ESPILEGR--HALFVEASDQ 541
N F +NP++G +SV+ E GR ++L + A+D+
Sbjct: 895 GNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDK 936
Score = 52.8 bits (121), Expect = 7e-05
Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V V + D NDN PVF+ + Y S+K N +GT VKA D D GQN ++ Y +
Sbjct: 118 VPVRVQIEDVNDNTPVFI-NTPYSISVKENT-LGTTGFAVKATDADQGQNALIKYSITGG 175
Query: 503 SNLTITSPFKINPNTGTVSV-AESPILE 529
+ + FKI GT+SV +S +L+
Sbjct: 176 NEANM---FKIGAYEGTISVFPDSGVLD 200
Score = 52.0 bits (119), Expect = 1e-04
Identities = 49/161 (30%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELD---LDAEHNLQANTFVLQVQASQLNNPLKT 287
+ Y+L SG D + F ++SV G + +D L + L+ + + + +
Sbjct: 61 ITYQL-SGEDGR-FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDV 118
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
RV+IE D+NDN P F Y+IS+ EN G + V ATD DQG+N Y +
Sbjct: 119 P-VRVQIE--DVNDNTPVFINTPYSISVKEN-TLGTTGFAVKATDADQGQNALIKYSITG 174
Query: 348 PKGA--FSIDPRSGWLTV-RNQTVLDREAHSSLRMKVYAKE 385
A F I G ++V + VLD E + S + V A +
Sbjct: 175 GNEANMFKIGAYEGTISVFPDSGVLDYEKYKSFNLTVSASD 215
Score = 50.8 bits (116), Expect = 3e-04
Identities = 66/229 (28%), Positives = 99/229 (43%), Gaps = 31/229 (13%)
Query: 407 PLETNAPLEKTTYVF-PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
PL+ E T VF D G + I D + V V + D NDN+PVF P + Y
Sbjct: 713 PLDREVRAEYTLLVFVSDLQGNASLGIPLRDSAV-----VNVFIEDMNDNSPVF-PQSQY 766
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
++ + GT I +V+A D D G + + Y + ++L F I+ ++ V V +S
Sbjct: 767 SLTIPEDTAPGTGIIQVQARDIDSGISQNLHYSIVSGNSL---GRFFIDSSSARVYV-KS 822
Query: 526 PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
P+ D P N E Y+L V +T + P P+F A Y + N
Sbjct: 823 PL----------DRDPPRN--EGAYTLEVT---ITISDVNDSP--PEFSQAMYSVRIPEN 865
Query: 586 VGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP-FAVEERSGVITV 631
+ +GT V Q D +SY + G E P F+V SG ++V
Sbjct: 866 ITLGTVVLQPSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSV 914
Score = 47.6 bits (108), Expect = 0.003
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 286 KTAQARVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
K + + + L D+NDN P F + Y + E G SV V ATD+D G N Y
Sbjct: 527 KEVTSSLTVILDDVNDNAPVFSRPEGYTFEVQEG-GVGLSVGTVQATDRDSGINAATLYS 585
Query: 345 LDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
L F ID ++G ++ LDRE L ++V A++T
Sbjct: 586 LKSVADYSKFIIDSKTG--VIKTSFSLDRETQDQLNIRVIARDT 627
Score = 44.4 bits (100), Expect = 0.024
Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 20/141 (14%)
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGA---IGHHPTASRTVRADT 1422
V + I D+NDN+PKF N P +P +P G V+++ G + + ++
Sbjct: 314 VQITITDINDNAPKFVN--LPYSGTVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGAA 371
Query: 1423 DELVFFER----LSLNGLTSPQAT--------DSDIGINADIRYQILNEQA---PRFAID 1467
+ V +S N Q T D+D+G NAD+R+ + + + F ID
Sbjct: 372 GKFVVSSEGYVVVSGNIDRETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTID 431
Query: 1468 PVSGTVRVVAALARDAGRVFG 1488
PVSG ++ +A R+ +G
Sbjct: 432 PVSGDIKTLATFDREERVSYG 452
Score = 39.5 bits (88), Expect = 0.69
Identities = 16/36 (44%), Positives = 24/36 (66%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ + +V + I D+NDN P F++ PY TV E +PTG
Sbjct: 309 AVFATVQITITDINDNAPKFVNLPYSGTVPENSPTG 344
Score = 38.7 bits (86), Expect = 1.2
Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-IVENLPNGFSVLQVMATDKDQGENG 339
+ NP +E L+ N P V+ + + EN P G VL V A D EN
Sbjct: 3 VTNPWIFVLLLIEAALIQGQANSPPRFVETQYVGRLPENQPTGTGVLTVRAVDN---END 59
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ TYQL G F I+ +G +T + +DRE
Sbjct: 60 QITYQLSGEDGRFKINSVTGEIT--SNVNIDRE 90
Score = 38.7 bits (86), Expect = 1.2
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 47 DSPQNVVKFRLGCDFDEGDDL-VRIGA---GLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
DS V+K D + D L +R+ A G Q+SA + + V + D+ND+ P F Y
Sbjct: 598 DSKTGVIKTSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQY 657
Query: 103 HVTVDE 108
VTV E
Sbjct: 658 SVTVQE 663
Score = 37.5 bits (83), Expect = 2.8
Identities = 40/149 (26%), Positives = 63/149 (42%), Gaps = 19/149 (12%)
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
I+ + ++PP F Y G + EN GT + ++A D + N Y L GE
Sbjct: 19 IQGQANSPPRFVETQYVGRLPENQPTGTGVL---TVRAVDNE---NDQITYQLSGEDGR- 71
Query: 837 FDVDENTGVVKFIGDSLDREK---KIMYKLSLVARDTGGLS----SEAELIIMIGDENDN 889
F ++ TG + ++DREK + + +A D G + + + I D NDN
Sbjct: 72 FKINSVTGEIT-SNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRVQIEDVNDN 130
Query: 890 KPEFNQIEENSKVRIHRETKLNGTAGFTI 918
P F N+ I + GT GF +
Sbjct: 131 TPVF----INTPYSISVKENTLGTTGFAV 155
Score = 37.5 bits (83), Expect = 2.8
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
Query: 1439 PQATDSDIGINADIRYQILN---EQAPRFAIDPVSGTVRVVAALARDAGR 1485
P D D+G N I Y I + E PRF+++P SG + V D GR
Sbjct: 875 PSCVDRDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGR 924
>UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor
variable 6; n=16; Clupeocephala|Rep: Cadherin-related
neuronal receptor variable 6 - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 939
Score = 111 bits (266), Expect = 2e-22
Identities = 111/468 (23%), Positives = 199/468 (42%), Gaps = 35/468 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ EV +LD NDN+P F PS+ + ++ A +G A D D+G N + Y L
Sbjct: 111 LNMYRFEVNVLDVNDNSPTF-PSSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKL 169
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLAVVT 556
+ ++ + + V + + + L + A D P + V
Sbjct: 170 SANEHFSLDAQSGGEQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNV 229
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL-HG 613
I+V +IP F + Y+ + N + SV + DA ++ Y + HG
Sbjct: 230 IDVN-------DNIPVFTKSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHG 282
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-TNATVHVVDVND 671
++ + FA+ + +G ITV+ L + + A + + + V ++DVND
Sbjct: 283 IDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVND 342
Query: 672 ERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ + + + +I VKE S G +G I + S G+V+ I +
Sbjct: 343 N---IPEISVTSLINVVKEGSPKGTMVGLITVKDDDS---GENGSVKLKILDSLPFALQN 396
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
++ PLDRE Y +T+ A ++G + + +++ D NDN P F
Sbjct: 397 TYKNKYSLVVDGPLDRESASEYNVTISAA-DEGSPPLSSTSVIAVHVSDVNDNAPRFPEP 455
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFDVDENTGV 845
++ ENS+IG + + + A D D G NA Y+L K M +++ +TG
Sbjct: 456 VINVYVKENSQIGAVL---HTVSAVDPDVGDNARITYSLLESSKSGPVTSMININSDTGD 512
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+ + S + E+ ++ + A D+G LSS + + + DENDN P
Sbjct: 513 LHSL-QSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSP 559
Score = 94.3 bits (224), Expect = 2e-17
Identities = 127/458 (27%), Positives = 199/458 (43%), Gaps = 41/458 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V++ V ++D NDN PVF S LY+ + NA V + V A D D G NG + Y +
Sbjct: 223 VHIIVNVIDVNDNIPVFTKS-LYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKH 281
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTIEVT 560
F IN TG ++V E +A+ V+A D+ + P + V ++V
Sbjct: 282 GIDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVN 341
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGV 618
+IP+ V GT VG I V +D+ E V +L + +
Sbjct: 342 -------DNIPEISVTSLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKIL----DSL 390
Query: 619 PFAVEE--RSGVITVVDD-LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERG 674
PFA++ ++ VVD L R + Y+ A E + LS + VHV DVND
Sbjct: 391 PFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAP 450
Query: 675 VLLKGAHSPII-FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF---LIANQQD--VTD 728
+ P+I +VKENS IG + HT +S++ + N R L+ + + VT
Sbjct: 451 RFPE----PVINVYVKENSQ---IGAVLHT-VSAVDPDVGDNARITYSLLESSKSGPVTS 502
Query: 729 DIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I I D G + + + + E+ + V A + GV + V +++ DENDN P
Sbjct: 503 MININSDTGDLHSLQSFNYEEIKTFEFKVQAT-DSGVPPLSSNVTVNVFVLDENDNSPAI 561
Query: 788 --EHATYEGFIMENSKIGTEIKMDNI-IKATDADEGTNALFMYTLF-GEGKEMFDVDENT 843
++ EN E I+A DAD G NAL Y + +G +F + ++
Sbjct: 562 LAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNLFRIGTSS 621
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
G ++ D + K + L ++ D G S A + I
Sbjct: 622 GEIRTKRRMSDNDLK-THPLVILVCDNGEPSLSATVSI 658
Score = 81.8 bits (193), Expect = 1e-13
Identities = 99/362 (27%), Positives = 157/362 (43%), Gaps = 36/362 (9%)
Query: 570 IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH-GYEEGVP----FAVEE 624
+P F V GT+VG I E N +L H G++ P F V
Sbjct: 21 LPRISSGQIAFSVSEEASPGTTVGNI----VKELNLNLQELEHRGFQIVGPNKRYFDVNM 76
Query: 625 RSGVITVVDDLSRYNRPMYDFE-AVALQENANLSI-VTNATVHVVDVNDERGVLLKGAHS 682
++G++ V D L R + A+ L+ N + + V+V+DVND S
Sbjct: 77 KTGILQVKDKLDREEICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTF---PSS 133
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF--LIANQQDVTDDIAIAEDGT--- 737
+ +V E A IG+ + + G +V+ L AN+ D + E
Sbjct: 134 RLQLNVSE---AAFIGERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQSVSAE 190
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ QK LDREK+ V R+T+ A + G +G + + + D NDN PVF + Y+ I+
Sbjct: 191 LVLQKALDREKQPVIRLTLTA-VDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARIL 249
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFDVDENTGVVKFIGDSL 853
EN+ + + + A DAD G N Y+ G E F +++ TG + +G L
Sbjct: 250 ENAPVEFSV---ITVNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMG-KL 305
Query: 854 DREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
D E ++ + ARD G + ++++ I D NDN PE I S + + +E
Sbjct: 306 DHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPE---ISVTSLINVVKEGSPK 362
Query: 912 GT 913
GT
Sbjct: 363 GT 364
Score = 80.2 bits (189), Expect = 4e-13
Identities = 56/179 (31%), Positives = 95/179 (53%), Gaps = 22/179 (12%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLD-------SVNGSLFLEKELDLDAEHNLQANT 271
+A D D+G+ + Y+L S N+ FSLD SV+ L L+K LD + + ++
Sbjct: 153 NAFDADVGINSVKSYKL-SANEH--FSLDAQSGGEQSVSAELVLQKALDREKQPVIR--- 206
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
L + A P ++ + + ++D+NDN+P F Y I+EN P FSV+ V A
Sbjct: 207 --LTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFSVITVNAR 264
Query: 332 DKDQGENGEFTYQ-----LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D G NGE Y +D +F+I+ +G +TV + LD E+++++ ++V A++
Sbjct: 265 DADAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMGK--LDHESNNAIEIRVQARD 321
Score = 78.6 bits (185), Expect = 1e-12
Identities = 68/219 (31%), Positives = 98/219 (44%), Gaps = 21/219 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P+ ++I +NA D D+GLNG+I Y F K D + F IN+ G
Sbjct: 248 ILENAPVEFSVITVNARDADAGLNGEIEYSF--------IKHGID--KNIESFAINKETG 297
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLN--DNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V L ES + + A D G+ + V V + DVND+ P T V+
Sbjct: 298 EITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLINVVK 357
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL---TGVLSVNGELDRET 1112
E ++G + D D G+N ++ I S LPF + L V+G LDRE+
Sbjct: 358 EGSPKGTMVGLITVKDDDSGENGSVKLKILDS---LPFALQNTYKNKYSLVVDGPLDRES 414
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +T+ A D G DVNDN+P+F
Sbjct: 415 ASEYNVTISAADEG-SPPLSSTSVIAVHVSDVNDNAPRF 452
Score = 72.5 bits (170), Expect = 8e-11
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 13/210 (6%)
Query: 946 IGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
IG NA D D G+N Y+ ++ + S V V+ + A
Sbjct: 145 IGERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQSVSAELVLQK-------AL 197
Query: 1006 SLPPESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRV 1063
+ RL ++A+DGG + +V + V DVND+ PVF K+ Y + E
Sbjct: 198 DREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFS 257
Query: 1064 LGKVDATDADFGQNANLTY-FIQPS-DTDL-PFEISPLTGVLSVNGELDRETEDKYILTV 1120
+ V+A DAD G N + Y FI+ D ++ F I+ TG ++V G+LD E+ + + V
Sbjct: 258 VITVNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMGKLDHESNNAIEIRV 317
Query: 1121 VARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
ARD G DVNDN P+
Sbjct: 318 QARDKG-STPRVAHCKVLVEIMDVNDNIPE 346
Score = 69.7 bits (163), Expect = 6e-10
Identities = 80/318 (25%), Positives = 136/318 (42%), Gaps = 30/318 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPR 136
A+ V V I DVNDN+P T V E +P G + + G + ++ L +
Sbjct: 329 AHCKVLVEIMDVNDNIPEISVTSLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKILD 388
Query: 137 GLTI-----FKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDY 190
L +K+ + D P S Y++ +S D+G L S+ ++ V D
Sbjct: 389 SLPFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTS---VIAVHVSDV 445
Query: 191 DAGDKEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELI----SGNDRKLFS 245
+ F ++ + + +I + A+D D+G A + Y L+ SG + +
Sbjct: 446 NDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSGPVTSMIN 505
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
++S G L + + + + TF +VQA+ P ++ V + +LD NDN P
Sbjct: 506 INSDTGDLHSLQSFNYE-----EIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPA 560
Query: 306 FEVDFYNISIV--ENLPN----GFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPR 357
+ + V EN+P G+ V ++ A D D G N +Y + +PKG F I
Sbjct: 561 ILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNLFRIGTS 620
Query: 358 SGWL-TVRNQTVLDREAH 374
SG + T R + D + H
Sbjct: 621 SGEIRTKRRMSDNDLKTH 638
Score = 65.7 bits (153), Expect = 9e-09
Identities = 56/246 (22%), Positives = 106/246 (43%), Gaps = 11/246 (4%)
Query: 218 IHAIDQDLGVGATLRYELIS-GNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G+ + Y I G D+ + F+++ G + + +LD ++ N +
Sbjct: 261 VNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMGKLDHESN-----NAIEI 315
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+VQA + + A +V +E++D+NDN+PE V + E P G V + D D
Sbjct: 316 RVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLINVVKEGSPKGTMVGLITVKDDD 375
Query: 335 QGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV-YAKETNPSVVG 392
GENG + LD A ++ + V + LDRE+ S + + A E +P +
Sbjct: 376 SGENGSVKLKILDSLPFALQNTYKNKYSLVVDGP-LDRESASEYNVTISAADEGSPPLSS 434
Query: 393 TFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDA 452
T + ++ P+ ++G + D + + +LL++
Sbjct: 435 TSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLES 494
Query: 453 NDNNPV 458
+ + PV
Sbjct: 495 SKSGPV 500
Score = 61.7 bits (143), Expect = 2e-07
Identities = 67/249 (26%), Positives = 100/249 (40%), Gaps = 23/249 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++E+ N ++ + ++ E P GT + + D DSG NG ++ +
Sbjct: 334 LVEIMDVNDNIPEISVTSLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKI------- 386
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRV 1033
D+L ++ ++V L ES E+ + ISA D G+ L+ + V
Sbjct: 387 -----LDSLPFALQNTYKNKYS-LVVDGPLDRESASEYNVTISAADEGSPPLSSTSVIAV 440
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP- 1092
V DVND+ P F + N V+E VL V A D D G NA +TY + S P
Sbjct: 441 HVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSGPV 500
Query: 1093 ---FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
I+ TG L + E + V A D+G D NDNSP
Sbjct: 501 TSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSG-VPPLSSNVTVNVFVLDENDNSP 559
Query: 1150 KFYA-FDEL 1157
A + EL
Sbjct: 560 AILAPYSEL 568
Score = 58.0 bits (134), Expect = 2e-06
Identities = 60/248 (24%), Positives = 101/248 (40%), Gaps = 15/248 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + D NDN P F P + +K N+++G V+ V AVDPD+G N + Y L +S
Sbjct: 438 IAVHVSDVNDNAPRF-PEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSK 496
Query: 505 L-TITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+TS IN +TG + +S E V+A+D P ++ V ++
Sbjct: 497 SGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDEND 556
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-- 619
+ + +G+ + + G V +IR DA D Y+ L Y P
Sbjct: 557 NSPAILAPYSE-LGSVNTENIPYSAEAGYFVAKIRAVDA----DSGYNALLSYHISEPKG 611
Query: 620 ---FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F + SG I +S + + + + +N S+ ++ V V V
Sbjct: 612 NNLFRIGTSSGEIRTKRRMSDNDLKTHPL-VILVCDNGEPSLSATVSIDAVVVESGGDVK 670
Query: 677 LKGAHSPI 684
H+P+
Sbjct: 671 TPFRHAPV 678
Score = 56.4 bits (130), Expect = 6e-06
Identities = 55/198 (27%), Positives = 83/198 (41%), Gaps = 21/198 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN IG + ++A+D D G N +I Y S+ + V IN G
Sbjct: 461 VKENSQIGAVLHTVSAVDPDVGDNARITYSLLE---------SSKSGPVTSMININSDTG 511
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF--- 1052
+ +S E F + A D G L+ N++V VFV D ND+ P +
Sbjct: 512 DLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSV 571
Query: 1053 NVEEAQYTRRV---LGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGEL 1108
N E Y+ + K+ A DAD G NA L+Y I +P +L F I +G + +
Sbjct: 572 NTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNL-FRIGTSSGEIRTKRRM 630
Query: 1109 DRETEDKYILTVVARDNG 1126
+ L ++ DNG
Sbjct: 631 SDNDLKTHPLVILVCDNG 648
Score = 55.2 bits (127), Expect = 1e-05
Identities = 63/248 (25%), Positives = 93/248 (37%), Gaps = 16/248 (6%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V+V+DVND V K + I EN+ + + NG F+
Sbjct: 227 VNVIDVNDNIPVFTKSLYKARIL---ENAPVEFSVITVNARDADAGLNGEIEYSFIKHGI 283
Query: 724 QDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ AI E G I LD E + + V A +KG +V + I D ND
Sbjct: 284 DKNIESFAINKETGEITVMGKLDHESNNAIEIRVQAR-DKGSTPRVAHCKVLVEIMDVND 342
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
N P + + E S GT M +I D D G N +
Sbjct: 343 NIPEISVTSLINVVKEGSPKGT---MVGLITVKDDDSGENGSVKLKILDSLPFALQNTYK 399
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ----- 895
+ LDRE Y +++ A D G LSS + + + + D NDN P F +
Sbjct: 400 NKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINV 459
Query: 896 -IEENSKV 902
++ENS++
Sbjct: 460 YVKENSQI 467
Score = 48.0 bits (109), Expect = 0.002
Identities = 52/174 (29%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Query: 989 KRYFVINERHGHVIVARSLPPES------EFRLNISALDGGNLNDNISVRVFVKDVNDHF 1042
KRYF +N + G + V L E + L + A+ LN V V DVND+
Sbjct: 69 KRYFDVNMKTGILQVKDKLDREEICGQSLKCALELEAIVNSPLN-MYRFEVNVLDVNDNS 127
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-----DTDLPFEISP 1097
P F + NV EA + +A DAD G N+ +Y + + D E S
Sbjct: 128 PTFPSSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQS- 186
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ L + LDRE + LT+ A D G DVNDN P F
Sbjct: 187 VSAELVLQKALDREKQPVIRLTLTAVDGG-KPPRSGTVHIIVNVIDVNDNIPVF 239
Score = 44.8 bits (101), Expect = 0.018
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 10/153 (6%)
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
I G +++ F ++ G L ++ +LD + E Q+ L+++A +N+PL R E+
Sbjct: 64 IVGPNKRYFDVNMKTGILQVKDKLDRE-EICGQSLKCALELEAI-VNSPLN--MYRFEVN 119
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
+LD+NDN P F +++ E G A D D G N +Y+L FS+D
Sbjct: 120 VLDVNDNSPTFPSSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKL-SANEHFSLD 178
Query: 356 PRSGW-----LTVRNQTVLDREAHSSLRMKVYA 383
+SG + Q LDRE +R+ + A
Sbjct: 179 AQSGGEQSVSAELVLQKALDREKQPVIRLTLTA 211
Score = 43.2 bits (97), Expect = 0.056
Identities = 67/306 (21%), Positives = 118/306 (38%), Gaps = 30/306 (9%)
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F+++ TG+L V +LDRE L DVNDNSP F
Sbjct: 72 FDVNMKTGILQVKDKLDREEICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTFP 131
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA--KVFANDTDFIGNG 1210
+ L+ EA + E + + A + N+ ++ + F+ D G
Sbjct: 132 S--SRLQLNVSEAAFIG----ERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQ 185
Query: 1211 N---GLILYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFI 1258
+ L+L R+ Q + G P S T ++V V DV D + PVF
Sbjct: 186 SVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNI-----PVFT 240
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
Y+ I EN ++++N + N ++ Y + +F I+ G +
Sbjct: 241 KSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETGEIT 300
Query: 1317 LVRSPDREVKDTYEVIVRAERQKYSRELPH-MIYPVAEDVLEGMTKYDVKVVVRIKDVND 1375
++ D E + E+ V+A + + + H + DV + + + V ++ + V +
Sbjct: 301 VMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLINV--VKE 358
Query: 1376 NSPKFT 1381
SPK T
Sbjct: 359 GSPKGT 364
Score = 41.1 bits (92), Expect = 0.23
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP-SNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQNG 493
L S V V V +LD NDN+P + P S L + ++ +A+ G + K++AVD D G N
Sbjct: 541 LSSNVTVNVFVLDENDNSPAILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNA 600
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV 520
++ Y + + F+I ++G +
Sbjct: 601 LLSYHISEPKGNNL---FRIGTSSGEI 624
>UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52;
Euteleostomi|Rep: Protocadherin-1 precursor - Homo
sapiens (Human)
Length = 1026
Score = 111 bits (266), Expect = 2e-22
Identities = 132/492 (26%), Positives = 211/492 (42%), Gaps = 45/492 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ VT+LD NDN P F + YE + N+ +G + +VKA D D G N + Y +
Sbjct: 232 LRVTVLDTNDNAPKFERPS-YEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPE 290
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQPANPSERRYSLAVVTIEVTRG 562
+ + +++ NTG ++V E L V A D+ NP R + VVT+ +
Sbjct: 291 V-VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQV-VVTV---KD 345
Query: 563 TKGNKPDIPDFMGAPYEFW------VGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
N P I + G + +V T+V ++V+D E + + + +
Sbjct: 346 MNDNAPTI-EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGD- 403
Query: 617 GVPFAVEERSGVITVVDDLSRY----NRPM-------YDFEAVALQE-NANLSIVTNATV 664
VPF + + S T D +Y P+ Y E VA+ N LS + V
Sbjct: 404 -VPFQLRQASE--TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKV 460
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
VVDVND V + + + F + N G I +I ++ S + + + +
Sbjct: 461 QVVDVNDNAPVFTQSV-TEVAFP-ENNKPGEVIAEITASDADS---GSNAELVYSLEPEP 515
Query: 725 DVTDDIAIA-EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
I+ E G I + LDRE+R+ Y + V+A ++G S G V + + D NDN
Sbjct: 516 AAKGLFTISPETGEIQVKTSLDREQRESYELKVVAA-DRGSPSLQGTATVLVNVLDCNDN 574
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F + Y +MEN + + M +I D D+G NA ++ + + F + T
Sbjct: 575 DPKFMLSGYNFSVMENMPALSPVGMVTVI---DGDKGENAQVQLSVEQDNGD-FVIQNGT 630
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSK 901
G + S DRE++ Y L A D G S+ + I + DENDN P S
Sbjct: 631 GTI-LSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSH 689
Query: 902 VRIHRETKLNGT 913
+ +T+L T
Sbjct: 690 KLLTPQTRLGET 701
Score = 110 bits (265), Expect = 2e-22
Identities = 123/467 (26%), Positives = 203/467 (43%), Gaps = 40/467 (8%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
++ + D NDN P F S + ++ N +G++ A D D G NG+ Y+LQ +
Sbjct: 133 QIEVQDINDNTPNFA-SPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQVAEDQ 191
Query: 506 TITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKG 565
P I +S + L ++ D + P L V ++ T
Sbjct: 192 EEKQPQLIVMGNLDRERWDS------YDLTIKVQDGGSPPRATSALLRVTVLD----TND 241
Query: 566 NKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVP--FAV 622
N P F YE + N IG SV Q++ ND+ + + + H E V +
Sbjct: 242 NAPK---FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRL 298
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL-LKG- 679
+ +G+ITV + R + F +A N S V V D+ND + ++G
Sbjct: 299 DRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGI 358
Query: 680 ---AHSPIIFHVKENSA---GAAIGQIFHTNM---SSIYGNGTGNVRFLIANQQDVTDDI 730
H + ++ E+ A A+ Q+ + +++ G+V F + + D
Sbjct: 359 GLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDS 418
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ + T PLD EK Y + ++A + G + + + + D NDN PVF +
Sbjct: 419 K--KKYFLQTTTPLDYEKVKDYTIEIVA-VDSGNPPLSSTNSLKVQVVDVNDNAPVFTQS 475
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE--GKEMFDVDENTGVVKF 848
E EN+K G I I A+DAD G+NA +Y+L E K +F + TG ++
Sbjct: 476 VTEVAFPENNKPGEVIAE---ITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ- 531
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ SLDRE++ Y+L +VA D G L A +++ + D NDN P+F
Sbjct: 532 VKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKF 578
Score = 94.7 bits (225), Expect = 2e-17
Identities = 109/436 (25%), Positives = 175/436 (40%), Gaps = 34/436 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E++ T + + D D G N + +V + S + K+ + +
Sbjct: 370 ISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQ---- 425
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++ + I A+D GN L+ S++V V DVND+ PVF ++ E
Sbjct: 426 -TTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPEN 484
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKY 1116
V+ ++ A+DAD G NA L Y ++P F ISP TG + V LDRE + Y
Sbjct: 485 NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESY 544
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L VVA D G D NDN PKF L + + + V
Sbjct: 545 ELKVVAADRG-SPSLQGTATVLVNVLDCNDNDPKFM----LSGYNFSVMENMP--ALSPV 597
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNL-------- 1227
M+ V ENA + +V + ++ DF I NG G IL SL + QQ+
Sbjct: 598 GMVTVIDGDKGENAQVQLSVEQ---DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAV 654
Query: 1228 --GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
G+P S+ + + V D D P S + L + + V V+ +
Sbjct: 655 DGGVPPRSAYVGVTINVLDENDNAPYITAPSNTS-HKLLTPQTRLGETVSQVAAEDFDSG 713
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR-AERQKYSREL 1344
N ++ Y I N + F I +G + L + +R + ++V+ ++R K R
Sbjct: 714 VNAELIYSIAGGNPYGL---FQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYG 770
Query: 1345 PHMIYPVAEDVLEGMT 1360
+++ + L T
Sbjct: 771 TALVHLYVNETLANRT 786
Score = 84.6 bits (200), Expect = 2e-14
Identities = 133/515 (25%), Positives = 204/515 (39%), Gaps = 72/515 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN IG+ A D D+G NG YE +++ D E+
Sbjct: 155 IPENTNIGSLFPIPLASDRDAGPNGVASYEL---------QVAEDQ---------EEKQP 196
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+IV +L E + L I DGG+ S +RV V D ND+ P F++ Y +
Sbjct: 197 QLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFERPSYEAELS 256
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQ-PSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + +V A D+D G NA + Y F Q P + TG+++V G +DRE
Sbjct: 257 ENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDL 316
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+V+A+D G D+NDN+P L +S
Sbjct: 317 STLRFSVLAKDRG-TNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 375
Query: 1174 E--SVMMIPVYKATIEENAPIGTTVAKVF------ANDTDFIGNGNGLILYSLP---QRK 1222
E +V ++ V ENA + VA A++T + + P ++
Sbjct: 376 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKV 435
Query: 1223 NQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
+ G P LSST L V V DV D + PVF E+ EN N P E
Sbjct: 436 KDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND-----NAPVFTQSVTEVAFPEN-NKPGE 489
Query: 1276 LVS-LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV-IV 1333
+++ + ++ E + + F I P G + + S DRE +++YE+ +V
Sbjct: 490 VIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVV 549
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF--TNGNRPLVTAI 1391
A+R S L+G V+V + D NDN PKF + N ++ +
Sbjct: 550 AADRGSPS--------------LQG----TATVLVNVLDCNDNDPKFMLSGYNFSVMENM 591
Query: 1392 PTTAPFGYQVMQLKGAIGHHPTASRTVRADTDELV 1426
P +P G V + G G + +V D + V
Sbjct: 592 PALSPVG-MVTVIDGDKGENAQVQLSVEQDNGDFV 625
Score = 81.8 bits (193), Expect = 1e-13
Identities = 73/257 (28%), Positives = 124/257 (48%), Gaps = 27/257 (10%)
Query: 643 YDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPII-FHVKENSAGAAIGQIF 701
++ L +NA+ ++ + V D+ND SP+I + EN+ IG +F
Sbjct: 114 FEVSITDLVQNASPRLL-EGQIEVQDINDNT----PNFASPVITLAIPENTN---IGSLF 165
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEF 760
++S G V + + V +D + + LDRE+ D Y +T+ + +
Sbjct: 166 PIPLASDRDAGPNGVA---SYELQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDG 221
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ + + +VT+ D NDN P FE +YE + ENS IG + +KA D+D+G
Sbjct: 222 GSPPRATSALLRVTVL--DTNDNAPKFERPSYEAELSENSPIGHSVIQ---VKANDSDQG 276
Query: 821 TNALFMYTLFGEGKE----MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD--TGGLS 874
NA YT F + E + +D NTG++ G +DRE + S++A+D T S
Sbjct: 277 ANAEIEYT-FHQAPEVVRRLLRLDRNTGLITVQG-PVDREDLSTLRFSVLAKDRGTNPKS 334
Query: 875 SEAELIIMIGDENDNKP 891
+ A++++ + D NDN P
Sbjct: 335 ARAQVVVTVKDMNDNAP 351
Score = 80.6 bits (190), Expect = 3e-13
Identities = 60/182 (32%), Positives = 87/182 (47%), Gaps = 19/182 (10%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
LFP P+ A D+D G YEL D+ + L + LD + + +++
Sbjct: 164 LFPIPL-ASDRDAGPNGVASYELQVAEDQ-----EEKQPQLIVMGNLDRE-----RWDSY 212
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L ++ +P + A + + +LD NDN P+FE Y + EN P G SV+QV A D
Sbjct: 213 DLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKAND 272
Query: 333 KDQGENGEFTYQLDDP----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE--T 386
DQG N E Y + +D +G +TV Q +DRE S+LR V AK+ T
Sbjct: 273 SDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITV--QGPVDREDLSTLRFSVLAKDRGT 330
Query: 387 NP 388
NP
Sbjct: 331 NP 332
Score = 79.0 bits (186), Expect = 9e-13
Identities = 93/381 (24%), Positives = 158/381 (41%), Gaps = 21/381 (5%)
Query: 414 LEKTTYVFPDKVGTKTENIEYYDE---QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMK 470
L+ TT + +KV T I D L S +++V ++D NDN PVF S + E +
Sbjct: 424 LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQS-VTEVAFP 482
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG 530
N K G VI ++ A D D G N ++Y L+ F I+P TG + V S E
Sbjct: 483 ENNKPGEVIAEITASDADSGSNAELVYSLE--PEPAAKGLFTISPETGEIQVKTSLDREQ 540
Query: 531 R--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
R + L V A+D+ +PS + + +V + N D P FM + Y F V N+
Sbjct: 541 RESYELKVVAADR-GSPSLQGTATVLVNV-----LDCNDND-PKFMLSGYNFSVMENMPA 593
Query: 589 GTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAV 648
+ VG + V D + + L + G F ++ +G I R + Y F+
Sbjct: 594 LSPVGMVTVIDGDKGENAQVQLSVEQDNG-DFVIQNGTGTILSSLSFDREQQSTYTFQLK 652
Query: 649 ALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
A+ S T++V+D ND + +++ + G + Q+ + S
Sbjct: 653 AVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDS 712
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
+ + IA + G I +K ++R ++R+ V+ ++G
Sbjct: 713 ---GVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRL-VVKVSDRGKPPR 768
Query: 768 AGIYQVTIYIEDENDNPPVFE 788
G V +Y+ + N + E
Sbjct: 769 YGTALVHLYVNETLANRTLLE 789
Score = 77.0 bits (181), Expect = 4e-12
Identities = 97/380 (25%), Positives = 166/380 (43%), Gaps = 41/380 (10%)
Query: 45 DSDSPQNVVKFRLGCD-FDEGDDLVRI---GAGLNQISAYLSVTVYIEDVNDNVPIFLDT 100
+ PQ +V L + +D D +++ G+ SA L VTV D NDN P F
Sbjct: 192 EEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVL--DTNDNAPKFERP 249
Query: 101 PYHVTVDELTPTGEKAFIFLI--APIGPSLTIPLTVPRGLTIFKDIRAFDRDK------- 151
Y + E +P G + G + I T + + + + DR+
Sbjct: 250 SYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQG 309
Query: 152 --PNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ---LVIMASGK 206
S + +S+++ D G +S+ V++ K ++ +A E + LV G
Sbjct: 310 PVDREDLSTLRFSVLA-KDRGTNP-KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGM 367
Query: 207 RIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDRKLFSLDSVNGS-----LFLEK 257
E + E A+ D+D G A + +++G+ S GS FL+
Sbjct: 368 ANISEDVAEETAVALVQVSDRDEGENAAVTC-VVAGDVPFQLRQASETGSDSKKKYFLQT 426
Query: 258 ELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE 317
LD E + + +++ A NP ++ ++++++D+NDN P F ++ E
Sbjct: 427 TTPLDYE---KVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPE 483
Query: 318 NLPNGFSVLQVMATDKDQGENGEFTYQLD-DP--KGAFSIDPRSGWLTVRNQTVLDREAH 374
N G + ++ A+D D G N E Y L+ +P KG F+I P +G + V+ T LDRE
Sbjct: 484 NNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVK--TSLDREQR 541
Query: 375 SSLRMKVYAKET-NPSVVGT 393
S +KV A + +PS+ GT
Sbjct: 542 ESYELKVVAADRGSPSLQGT 561
Score = 73.3 bits (172), Expect = 5e-11
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I A D D G A L Y L K LF++ G + ++ LD + Q ++ L+V
Sbjct: 494 ITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDRE-----QRESYELKV 548
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ +P A V + +LD NDN P+F + YN S++EN+P V V D D+G
Sbjct: 549 VAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKG 608
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
EN + ++ G F I +G T+ + DRE S+ ++ A
Sbjct: 609 ENAQVQLSVEQDNGDFVIQNGTG--TILSSLSFDREQQSTYTFQLKA 653
Score = 68.1 bits (159), Expect = 2e-09
Identities = 143/585 (24%), Positives = 238/585 (40%), Gaps = 89/585 (15%)
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
I ++D NDN P F I EN+ IG+ + I A+D D G N + Y L +
Sbjct: 134 IEVQDINDNTPNFASPVITLAIPENTNIGS---LFPIPLASDRDAGPNGVASYEL----Q 186
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
D +E + +G+ LDRE+ Y L++ +D G ++ A L + + D NDN P+
Sbjct: 187 VAEDQEEKQPQLIVMGN-LDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPK 245
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
F + E N G ++I+VK A D DQ N I T +
Sbjct: 246 F------ERPSYEAELSENSPIGHSVIQVK-----ANDSDQ-------GANAEIEYTFHQ 287
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
+ + +R + N+ + + + L R+ V+ + G + P +
Sbjct: 288 APEV-----VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRG------TNPKSAR 336
Query: 1013 FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
++ ++ D +NDN + + ++ + + N + + A+ T L V +D
Sbjct: 337 AQVVVTVKD---MNDN-APTIEIRGIG--LVTHQDGMANISEDVAEETAVAL--VQVSDR 388
Query: 1073 DFGQNANLTYFIQPSDTDLPFEI--SPLTG-------VLSVNGELDRETEDKYILTVVAR 1123
D G+NA +T + D+PF++ + TG L LD E Y + +VA
Sbjct: 389 DEGENAAVTCVVA---GDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAV 445
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D+G DVNDN+P F + E PE +N E + I
Sbjct: 446 DSG-NPPLSSTNSLKVQVVDVNDNAPVF--TQSVTEVAFPE----NNKPGEVIAEITASD 498
Query: 1184 ATIEENAPIGTTVAKVFANDTDFI---GNGNGLILYSLPQRKNQQ--------NLGLPSL 1232
A NA + ++ A F G + SL + + + + G PSL
Sbjct: 499 ADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSL 558
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA--PVELVSLNLTEHYENFKM 1290
TA ++V V D D + P F+ Y + EN+ A PV +V++ + EN ++
Sbjct: 559 QGTATVLVNVLDCND-----NDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQV 613
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + +N FVI GT+ S DRE + TY ++A
Sbjct: 614 QLSVEQDNG-----DFVIQNGTGTILSSLSFDREQQSTYTFQLKA 653
Score = 62.9 bits (146), Expect = 7e-08
Identities = 87/343 (25%), Positives = 136/343 (39%), Gaps = 27/343 (7%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--AP 123
++V + +G +S+ S+ V + DVNDN P+F + V E GE A
Sbjct: 441 EIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDAD 500
Query: 124 IGPSLTI-----PLTVPRGL-TIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALES 176
G + + P +GL TI + Y + V D G +L+
Sbjct: 501 SGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQG 560
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEP-IHAIDQDLGVGATLRYEL 235
+ +L VLD + D +F L + L P + ID D G A ++ +
Sbjct: 561 T---ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSV 617
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
N + NG+ + L D E Q +T+ Q++A P ++A V I
Sbjct: 618 EQDNGDFVIQ----NGTGTILSSLSFDRE---QQSTYTFQLKAVDGGVPPRSAYVGVTIN 670
Query: 296 LLDLNDNLPEFEV--DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGA 351
+LD NDN P + + + G +V QV A D D G N E Y + +P G
Sbjct: 671 VLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGL 730
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
F I SG +T+ + ++R H R+ V + P GT
Sbjct: 731 FQIGSHSGAITLEKE--IERRHHGLHRLVVKVSDRGKPPRYGT 771
Score = 58.0 bits (134), Expect = 2e-06
Identities = 123/557 (22%), Positives = 215/557 (38%), Gaps = 67/557 (12%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
++ +PE P T I L A D G + + + EV P ++ ++ +
Sbjct: 39 VYKVPEEQPPNTLIGSLAA---DYGFP-DVGHLYKLEVGAPYLRVDGKTGDIFTTETSID 94
Query: 997 RHGHVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
R G LP + EF ++I+ L + ++ V+D+ND+ P F
Sbjct: 95 REGLRECQNQLPGDPCILEFEVSITDLVQNASPRLLEGQIEVQDINDNTPNFASPVITLA 154
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ E + A+D D G N +Y +Q ++ E P L V G LDRE
Sbjct: 155 IPENTNIGSLFPIPLASDRDAGPNGVASYELQVAEDQE--EKQPQ---LIVMGNLDRERW 209
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
D Y LT+ +D G D NDN+PKF + P
Sbjct: 210 DSYDLTIKVQDGGSPPRATSALLRVTVL-DTNDNAPKF---------ERPS--------- 250
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLS 1233
Y+A + EN+PIG +V +V AND+D N I Y+ Q L
Sbjct: 251 --------YEAELSENSPIGHSVIQVKANDSD--QGANAEIEYTFHQAPEVVRRLLRLDR 300
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYY 1293
+T ++TV D ++S + ++ A V + ++ ++ ++R
Sbjct: 301 NTG--LITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGI 358
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
L + + + LV+ DR+ + V + ++P + +E
Sbjct: 359 GLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTC-----VVAGDVPFQLRQASE 413
Query: 1354 DVLEGMTKYDVKVVV-----RIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAI 1408
+ KY ++ ++KD +GN PL +T QV+ +
Sbjct: 414 TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPL----SSTNSLKVQVVDVN--- 466
Query: 1409 GHHPTASRTVRADTDELVFFERLSLNGLTSP-QATDSDIGINADIRYQILNEQAPR--FA 1465
+ P +++V E+ F E + + A+D+D G NA++ Y + E A + F
Sbjct: 467 DNAPVFTQSV----TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFT 522
Query: 1466 IDPVSGTVRVVAALARD 1482
I P +G ++V +L R+
Sbjct: 523 ISPETGEIQVKTSLDRE 539
Score = 43.6 bits (98), Expect = 0.043
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV---EIELLDLNDNLPEFEVDFY 311
+++E + ++ L + +L+ + S + + ++ A R+ +IE+ D+NDN P F
Sbjct: 93 IDREGLRECQNQLPGDPCILEFEVS-ITDLVQNASPRLLEGQIEVQDINDNTPNFASPVI 151
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
++I EN G +A+D+D G NG +Y+L
Sbjct: 152 TLAIPENTNIGSLFPIPLASDRDAGPNGVASYEL 185
>UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34;
Euteleostomi|Rep: Protocadherin-10 precursor - Homo
sapiens (Human)
Length = 1040
Score = 111 bits (266), Expect = 2e-22
Identities = 120/429 (27%), Positives = 180/429 (41%), Gaps = 45/429 (10%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G ++ + +DRE+ + + + + ++QV I + D NDNPP F
Sbjct: 69 ETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLT 128
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKFI 849
I E++ GT +++ A D D GTN+L Y + DV D N +
Sbjct: 129 VEISESATPGTRFPLES---AFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVL 185
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LDRE++ +++ L A D GG +G+ + + +
Sbjct: 186 EKPLDREQQAVHRYVLTAVDGGGGGG-------VGEGGGG---------GGGAGLPPQQQ 229
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
GTA TI V N DQ +PEN P GT +I+LNA D D G NG++ Y
Sbjct: 230 RTGTALLTI-RVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYS 288
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-GGN-L 1025
F+S +I P + F ++ R G + V+ L E +++ + A D G N +
Sbjct: 289 FSS--HISP--------RARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAV 338
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
+ V V V D ND+ P + V E V+ TD D +N + +
Sbjct: 339 PAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELL 398
Query: 1086 PSDTDLPFEI-SPLTGVLSVNGE--LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
D+PF + S ++ E LDRE D Y LTVVARD G
Sbjct: 399 ---GDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRG-EPALSTSKSIQVQVS 454
Query: 1143 DVNDNSPKF 1151
DVNDN+P+F
Sbjct: 455 DVNDNAPRF 463
Score = 108 bits (260), Expect = 1e-21
Identities = 125/494 (25%), Positives = 201/494 (40%), Gaps = 48/494 (9%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E + E + VE+ +LD NDN P F +L + +A GT A DPD+G
Sbjct: 94 HLEVFLENPLELFQVEIEVLDINDNPPSFPEPDL-TVEISESATPGTRFPLESAFDPDVG 152
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPAN--- 544
N + Y++ S ++ + + N V E P+ + H + A D
Sbjct: 153 TNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGV 212
Query: 545 -------------PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS 591
P ++R A++TI V + ++P F Y + N GT
Sbjct: 213 GEGGGGGGGAGLPPQQQRTGTALLTIRVL----DSNDNVPAFDQPVYTVSLPENSPPGTL 268
Query: 592 VGQIRVNDAFE-QN-DVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEA 647
V Q+ D E QN +V Y F + R+G + V +L P+Y
Sbjct: 269 VIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYV 328
Query: 648 VALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS 706
A N + V V+D ND + + S + V E +A + +F
Sbjct: 329 QAKDLGPNAVPAHCKVLVRVLDANDNAPEI---SFSTVKEAVSEGAAPGTVVALFSVTDR 385
Query: 707 SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS 766
NG V+ + + TI T+ PLDRE D Y +TV+A ++G +
Sbjct: 386 DSEENG--QVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVAR-DRGEPA 442
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+ + + + D NDN P F Y+ ++ EN+ G I + ATD DEG NA
Sbjct: 443 LSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYA---VSATDRDEGANAQLA 499
Query: 827 YTLFG---EGKEMF---DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEA 877
Y++ +G +F ++ G + + S D E+ + + ARD G L+ A
Sbjct: 500 YSILECQIQGMSVFTYVSINSENGYLYALR-SFDYEQLKDFSFQVEARDAGSPQALAGNA 558
Query: 878 ELIIMIGDENDNKP 891
+ I+I D+NDN P
Sbjct: 559 TVNILIVDQNDNAP 572
Score = 87.0 bits (206), Expect = 3e-15
Identities = 116/464 (25%), Positives = 191/464 (41%), Gaps = 46/464 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +LD+NDN P F +Y S+ N+ GT++ ++ A DPD GQNG V+Y +
Sbjct: 238 IRVLDSNDNVPAF-DQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPR 296
Query: 507 ITSPFKINPNTGTVSVA------ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F ++P TG + V+ ESP+ + ++V+A D N + V ++
Sbjct: 297 ARELFGLSPRTGRLEVSGELDYEESPV----YQVYVQAKDLGPNAVPAHCKVLVRVLD-- 350
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P+I F G+ G ++ + D+ E V +LL VPF
Sbjct: 351 --ANDNAPEI-SFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELL----GDVPF 403
Query: 621 AVEER-SGVITVVDD--LSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVL 676
++ T+V + L R Y VA LS + V V DVND
Sbjct: 404 RLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRF 463
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ----DVTDDIAI 732
+ + ++ + N GA I + T+ + + I Q V ++I
Sbjct: 464 SQPVYD--VYVTENNVPGAYIYAVSATDRDE---GANAQLAYSILECQIQGMSVFTYVSI 518
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF---- 787
+E+G ++ + D E+ + V A + AG V I I D+NDN P
Sbjct: 519 NSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPL 578
Query: 788 --EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
+ T ++ S + + A DAD+G NA Y++ G +F +D TG
Sbjct: 579 PGRNGTPAREVLPRS--AEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTG 636
Query: 845 VVKFIGD-SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
++ R+ + Y+L + RD G LSS A L++ + D
Sbjct: 637 ELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 74.1 bits (174), Expect = 3e-11
Identities = 42/111 (37%), Positives = 61/111 (54%), Gaps = 7/111 (6%)
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+T A + I +LD NDN+P F+ Y +S+ EN P G V+Q+ ATD D+G+NGE Y
Sbjct: 230 RTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSF 289
Query: 346 D---DPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
P+ F + PR+G L V + LD E ++ V AK+ P+ V
Sbjct: 290 SSHISPRARELFGLSPRTGRLEVSGE--LDYEESPVYQVYVQAKDLGPNAV 338
Score = 62.5 bits (145), Expect = 9e-08
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 8/179 (4%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y IS R+LF L G L + ELD + ++ + +
Sbjct: 272 LNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYE-----ESPVYQV 326
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
VQA L A +V + +LD NDN PE ++ E G V TD+D
Sbjct: 327 YVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRD 386
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
ENG+ +L + T+ + LDREA S + V A++ + T
Sbjct: 387 SEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALST 445
Score = 61.7 bits (143), Expect = 2e-07
Identities = 63/223 (28%), Positives = 87/223 (39%), Gaps = 22/223 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E GT + + D DS NGQ++ E +V P +L + K Y+ I
Sbjct: 367 VSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDV---PFRLKSS---FKNYYTI----- 415
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L E+ + L + A D G L+ + S++V V DVND+ P F + Y+ V
Sbjct: 416 --VTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVT 473
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYF-----IQPSDTDLPFEISPLTGVLSVNGELDR 1110
E + V ATD D G NA L Y IQ I+ G L D
Sbjct: 474 ENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDY 533
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
E + V ARD G D NDN+P A
Sbjct: 534 EQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVA 576
Score = 58.8 bits (136), Expect = 1e-06
Identities = 73/293 (24%), Positives = 125/293 (42%), Gaps = 29/293 (9%)
Query: 71 GAGL---NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAPI-G 125
GAGL Q + +T+ + D NDNVP F Y V++ E +P G + P G
Sbjct: 221 GAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEG 280
Query: 126 PSLTIPLTV-----PRGLTIF----KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALES 176
+ + + PR +F + R + + S V+ V D G A+ +
Sbjct: 281 QNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPA 340
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLR 232
H VL+ +VLD + E + ++ K E P + A+ D+D ++
Sbjct: 341 -HCKVLV--RVLDANDNAPE---ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQ 394
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
EL+ +L S ++ E LD +A +++ L V A P + +
Sbjct: 395 CELLGDVPFRLKSSFKNYYTIVTEAPLDREA-----GDSYTLTVVARDRGEPALSTSKSI 449
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
++++ D+NDN P F Y++ + EN G + V ATD+D+G N + Y +
Sbjct: 450 QVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSI 502
Score = 57.6 bits (133), Expect = 2e-06
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + LD E+ VY++ V A+ + G + +V + + D NDN P +T +
Sbjct: 308 GRLEVSGELDYEESPVYQVYVQAK-DLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEA 366
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E + GT + + ++ TD D N L G+ LDR
Sbjct: 367 VSEGAAPGTVVALFSV---TDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDR 423
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
E Y L++VARD G LS+ + + + D NDN P F+Q
Sbjct: 424 EAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQ 465
Score = 57.6 bits (133), Expect = 2e-06
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 23/204 (11%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+++ N+P G I ++A D D G N Q+ Y + + V Y IN
Sbjct: 470 VYVTENNVP-GAYIYAVSATDRDEGANAQLAYSI--------LECQIQGMSVFTYVSINS 520
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+G++ RS E +F + A D G+ L N +V + + D ND+ P
Sbjct: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
Query: 1052 FNVEEAQYTRR-------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
N A+ +L +V A DAD G+NA LTY I + F + TG L
Sbjct: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
Query: 1105 NGEL--DRETEDKYILTVVARDNG 1126
+ R+ + Y L + RD+G
Sbjct: 641 ARRVPAKRDPQRPYELVIEVRDHG 664
Score = 54.0 bits (124), Expect = 3e-05
Identities = 77/336 (22%), Positives = 128/336 (38%), Gaps = 30/336 (8%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSL 128
G N + A+ V V + D NDN P + V E G +F + + +
Sbjct: 334 GPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQV 393
Query: 129 TIPLT--VPRGL-TIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
L VP L + FK+ + P + Y++ V D G AL +S + +
Sbjct: 394 QCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQV 453
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL- 243
V D + + + + ++ + A D+D G A L Y ++ + +
Sbjct: 454 SDVNDNAPRFSQPVYDVYVTENNVPGAYIYA--VSATDRDEGANAQLAYSILECQIQGMS 511
Query: 244 ----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA-QARVEIELLD 298
S++S NG L+ + D + Q F QV+A +P A A V I ++D
Sbjct: 512 VFTYVSINSENGYLYALRSFDYE-----QLKDFSFQVEARDAGSPQALAGNATVNILIVD 566
Query: 299 LNDNLPEFEVDF---YNISIVENLPN----GFSVLQVMATDKDQGENGEFTYQL--DDPK 349
NDN P E LP G+ + +V A D D GEN TY + +
Sbjct: 567 QNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEM 626
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F +D R+G L + R+ + + ++
Sbjct: 627 NLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662
Score = 49.2 bits (112), Expect = 9e-04
Identities = 41/139 (29%), Positives = 67/139 (48%), Gaps = 9/139 (6%)
Query: 221 IDQDLGVGATLR----YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I +DLG+ T ++ + + L+ G L++ +++D + + Q+ + VL +
Sbjct: 37 IAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYVNEKIDRE-QICKQSPSCVLHL 95
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ L NPL+ Q VEIE+LD+NDN P F + I E+ G A D D G
Sbjct: 96 EVF-LENPLELFQ--VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVG 152
Query: 337 ENGEFTYQLDDPKGAFSID 355
N Y++ P FS+D
Sbjct: 153 TNSLRDYEI-TPNSYFSLD 170
Score = 44.0 bits (99), Expect = 0.032
Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 24/151 (15%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKM 1290
+ TA+L + V D D V D+PV Y + + EN ++ LN T+ E N ++
Sbjct: 231 TGTALLTIRVLDSNDNVPAFDQPV-----YTVSLPENSPPGTLVIQLNATDPDEGQNGEV 285
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
Y + R F + PR G L + D E Y+V V+
Sbjct: 286 VYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQ---------------- 329
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
A+D+ KV+VR+ D NDN+P+ +
Sbjct: 330 -AKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359
>UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15;
Eutheria|Rep: Protocadherin alpha 5 precursor - Homo
sapiens (Human)
Length = 936
Score = 110 bits (264), Expect = 3e-22
Identities = 121/425 (28%), Positives = 177/425 (41%), Gaps = 56/425 (13%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++G +F +DRE+ R V ++ V + ++D NDNPP F
Sbjct: 79 QNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQR 138
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
FI+E+ + ++ A+D D G NA Y L E FD+D T
Sbjct: 139 LFILESRMPDSRFPLEG---ASDLDIGANAQLRYRL--NPNEYFDLDVKTN--------- 184
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
E++ + L LV R + E +++ + KPE L GT
Sbjct: 185 --EEETNF-LELVLRKSLDREETQEHRLLVIATDGGKPE-----------------LTGT 224
Query: 914 AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
+I V N A + D+ + EN P GT +IKLNA D D G+N +I Y F
Sbjct: 225 VQL-LINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFF--- 280
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNI 1029
S L D +VK F+IN G + V L E + + +NI A+D L+ +
Sbjct: 281 -----SNLVLD--DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHC 333
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
V V + DVND+ P T V+E V+ + +D D G N +T + P
Sbjct: 334 KVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMP--- 390
Query: 1090 DLPFE-ISPLTGVLS--VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+PF+ +S S ++ LDRE+ Y L V ARD G DVND
Sbjct: 391 HVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGG-SPSLWATASVSVEVADVND 449
Query: 1147 NSPKF 1151
N+P F
Sbjct: 450 NAPAF 454
Score = 82.6 bits (195), Expect = 8e-14
Identities = 60/176 (34%), Positives = 89/176 (50%), Gaps = 18/176 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD---SVNGSLFLEKEL--DLDAEHNLQANTFVL 274
A D D+G A LRY L N + F LD + + FLE L LD E + V+
Sbjct: 156 ASDLDIGANAQLRYRL---NPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVI 212
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A+ P T ++ I +LD NDN PEF+ YN+ ++EN P+G V+++ A+D D
Sbjct: 213 ---ATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDAD 269
Query: 335 QGENGEFTY-----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G N E Y LDD K F I+ +G + V + LD E ++S + + A +
Sbjct: 270 EGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE--LDYEDYNSYEINIDAMD 323
Score = 81.0 bits (191), Expect = 2e-13
Identities = 107/452 (23%), Positives = 187/452 (41%), Gaps = 35/452 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V + + +LDANDN P F S +Y + NA GT++ K+ A D D G N ++Y
Sbjct: 220 ELTGTVQLLINVLDANDNAPEFDKS-IYNVRLLENAPSGTLVIKLNASDADEGINKEIVY 278
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVV 555
+ S F IN NTG + V E + + ++A D+ P + V
Sbjct: 279 FFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVK 338
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++V T P+ V + + T + I V+D + + +
Sbjct: 339 LLDVNDNT-------PEMAITTLFLPVKEDAPLSTVIALISVSD--RDSGANGQVTCSLM 389
Query: 616 EGVPF-AVEERSGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
VPF V ++V D L R + +Y+ A + +L + +V V DVND
Sbjct: 390 PHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVND 449
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQDVT 727
+ ++ +F VKEN+ IF + V + + ++ ++
Sbjct: 450 NAPAFAQPQYT--VF-VKENNPPGC--HIFTVSARDADAQENALVSYSLVERRVGERPLS 504
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+++ AE G ++ +PLD E+ ++ + V A + GV + +++ DENDN P
Sbjct: 505 SYVSVHAESGKVYALQPLDHEEVELLQFQVSAR-DAGVPPLGSNVTLQVFVLDENDNAPA 563
Query: 787 FEHATYEGFIMENSK-IGTEIKMDNI---IKATDADEGTNALFMYTLF---GEGKEMFDV 839
G S+ + + ++ ++A D D G NA Y L G + F V
Sbjct: 564 LLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFRV 623
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
TG + SLD + ++L ++ +D G
Sbjct: 624 GLYTGEIS-TTRSLDETEAPRHRLLVLVKDHG 654
Score = 75.4 bits (177), Expect = 1e-11
Identities = 117/479 (24%), Positives = 187/479 (39%), Gaps = 38/479 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E ++ + +VEV + D NDN P F F ++S + A D D+G
Sbjct: 104 HLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMP-DSRFPLEGASDLDIG 162
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPN-TGTVSVAESPILEGR----HALFVEASDQPANP 545
N + Y L + K N T + + L+ H L V A+D P
Sbjct: 163 ANAQLRYRLNPNEYFDLD--VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDG-GKP 219
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--Q 603
T+++ + P+F + Y + N GT V ++ +DA E
Sbjct: 220 E------LTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGIN 273
Query: 604 NDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVT 660
++ Y + + V F + +G I V +L + Y+ A+ ++ LS
Sbjct: 274 KEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHC 333
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
V ++DVND + A + + VKE++ + + I ++S G V +
Sbjct: 334 KVVVKLLDVNDNTPEM---AITTLFLPVKEDAPLSTV--IALISVSDRDSGANGQVTCSL 388
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
++ LDRE VY + V A + G S V++ + D
Sbjct: 389 MPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTAR-DGGSPSLWATASVSVEVADV 447
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEG--K 834
NDN P F Y F+ EN+ G I + A DAD NAL Y+L GE
Sbjct: 448 NDNAPAFAQPQYTVFVKENNPPGCHIFT---VSARDADAQENALVSYSLVERRVGERPLS 504
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
V +G V + LD E+ + + + ARD G L S L + + DENDN P
Sbjct: 505 SYVSVHAESGKVYAL-QPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAP 562
Score = 63.3 bits (147), Expect = 5e-08
Identities = 78/343 (22%), Positives = 137/343 (39%), Gaps = 23/343 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
++ G +++ + + + + D NDN P F + Y+V + E P+G +
Sbjct: 211 VIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADE 270
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTP----NSDVHYSIVSGNDDGHFALESSHKPVL 182
+ + + D+++ NT N ++ Y + + A++ S P+
Sbjct: 271 GINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLS 330
Query: 183 LLRKVLD--YDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELIS 237
KV+ D D ++ I + ++ I I D+D G + L+
Sbjct: 331 GHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMP 390
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
KL S SL L+ LD ++ + + L V A +P A A V +E+
Sbjct: 391 HVPFKLVSTFKNYYSLVLDSALDRES-----VSVYELVVTARDGGSPSLWATASVSVEVA 445
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL------DDPKGA 351
D+NDN P F Y + + EN P G + V A D D EN +Y L + P +
Sbjct: 446 DVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSS 505
Query: 352 F-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
+ S+ SG V LD E L+ +V A++ +G+
Sbjct: 506 YVSVHAESG--KVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546
Score = 60.9 bits (141), Expect = 3e-07
Identities = 61/221 (27%), Positives = 92/221 (41%), Gaps = 21/221 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV N A Q + EN P G I ++A D D+ N + Y E +
Sbjct: 442 VEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL-VERRVGE 500
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVF 1034
LS+ Y ++ G V + L E + +SA D G L N++++VF
Sbjct: 501 RPLSS-------YVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 553
Query: 1035 VKDVNDHFPVFKKTWYNFN-------VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
V D ND+ P V + V+ KV A D D G NA L+Y +QP+
Sbjct: 554 VLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPA 613
Query: 1088 --DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+PF + TG +S LD ++ L V+ +D+G
Sbjct: 614 PGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHG 654
Score = 60.1 bits (139), Expect = 5e-07
Identities = 44/188 (23%), Positives = 88/188 (46%), Gaps = 9/188 (4%)
Query: 218 IHAIDQDLGVGATLRY---ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G+ + Y L+ + + F ++S G + + ELD + N++ +
Sbjct: 263 LNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYE-----DYNSYEI 317
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A + + +V ++LLD+NDN PE + + + E+ P + + +D+D
Sbjct: 318 NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRD 377
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G NG+ T L + + ++ + LDRE+ S + V A++ +PS+ T
Sbjct: 378 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWAT 437
Query: 394 FADSQRIA 401
+ S +A
Sbjct: 438 ASVSVEVA 445
Score = 55.2 bits (127), Expect = 1e-05
Identities = 69/227 (30%), Positives = 98/227 (43%), Gaps = 32/227 (14%)
Query: 937 LFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
LFL + E+ P+ T I ++ D DSG NGQ+ V P KL + K Y+ +
Sbjct: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHV---PFKLVST---FKNYYSL- 406
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
++ +L ES + L ++A DGG+ L SV V V DVND+ P F + Y
Sbjct: 407 ------VLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYT 460
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE---- 1107
V+E + V A DAD +NA ++Y S + PL+ +SV+ E
Sbjct: 461 VFVKENNPPGCHIFTVSARDADAQENALVSY----SLVERRVGERPLSSYVSVHAESGKV 516
Query: 1108 -----LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
LD E + V ARD G D NDN+P
Sbjct: 517 YALQPLDHEEVELLQFQVSARDAG-VPPLGSNVTLQVFVLDENDNAP 562
Score = 52.0 bits (119), Expect = 1e-04
Identities = 57/237 (24%), Positives = 94/237 (39%), Gaps = 14/237 (5%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
++V+D ND K ++ + EN+ + + N S + + +N
Sbjct: 229 INVLDANDNAPEFDKSIYN---VRLLENAPSGTL--VIKLNASDADEGINKEIVYFFSNL 283
Query: 724 --QDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
DV I + G I LD E + Y + + A +K +G +V + + D
Sbjct: 284 VLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDA-MDKSTFPLSGHCKVVVKLLDV 342
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P T + E++ + T I + I +D D G N +L
Sbjct: 343 NDNTPEMAITTLFLPVKEDAPLSTVIAL---ISVSDRDSGANGQVTCSLMPHVPFKLVST 399
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ +LDRE +Y+L + ARD G L + A + + + D NDN P F Q
Sbjct: 400 FKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQ 456
Score = 45.6 bits (103), Expect = 0.011
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 24/154 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P L+ T L++ V D D DK + Y + + EN + ++ LN ++ E
Sbjct: 217 GKPELTGTVQLLINVLDANDNAPEFDKSI-----YNVRLLENAPSGTLVIKLNASDADEG 271
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y+ N D++ F+I+ G + + D E ++YE+ + A +
Sbjct: 272 INKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDA--------MD 323
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
+P L G KVVV++ DVNDN+P+
Sbjct: 324 KSTFP-----LSG----HCKVVVKLLDVNDNTPE 348
Score = 43.6 bits (98), Expect = 0.043
Identities = 80/331 (24%), Positives = 125/331 (37%), Gaps = 29/331 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT--- 133
+S + V V + DVNDN P T + V E P + ++ +T
Sbjct: 329 LSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSL 388
Query: 134 ---VPRGL-TIFKDIRAFDRDKPNTPNS-DVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
VP L + FK+ + D S V+ +V+ D G +L ++ + + V
Sbjct: 389 MPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVN 448
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN--DRKLFSL 246
D + Q + +F + A D D A + Y L+ +R L S
Sbjct: 449 DNAPAFAQPQYTVFVKENNPPGCHIFT--VSARDADAQENALVSYSLVERRVGERPLSSY 506
Query: 247 DSVN---GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
SV+ G ++ + LD + LQ QV A P + +++ +LD NDN
Sbjct: 507 VSVHAESGKVYALQPLDHEEVELLQ-----FQVSARDAGVPPLGSNVTLQVFVLDENDNA 561
Query: 304 PEF---EVDFYNISIVENLPN----GFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
P V ++ E +P G V +V A D D G N +Y+L G+ I
Sbjct: 562 PALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPF 621
Query: 357 RSGWLTVRNQTV--LDREAHSSLRMKVYAKE 385
R G T T LD R+ V K+
Sbjct: 622 RVGLYTGEISTTRSLDETEAPRHRLLVLVKD 652
Score = 43.2 bits (97), Expect = 0.056
Identities = 52/185 (28%), Positives = 88/185 (47%), Gaps = 19/185 (10%)
Query: 221 IDQDLGVG-ATL---RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQ 275
I QDLG+ A L + + S L ++ NG LF+ +D + +A + L+
Sbjct: 47 IAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLE 106
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKD 334
V ++ PL+ VE+ + D+NDN P F + I+E+ +P+ L+ A+D D
Sbjct: 107 VI---VDRPLQVFH--VEVAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLE-GASDLD 160
Query: 335 QGENGEFTYQLDDPKGAFSIDPR-----SGWLTVRNQTVLDREAHSSLRMKVYAKE-TNP 388
G N + Y+L +P F +D + + +L + + LDRE R+ V A + P
Sbjct: 161 IGANAQLRYRL-NPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKP 219
Query: 389 SVVGT 393
+ GT
Sbjct: 220 ELTGT 224
>UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|Rep:
Pcdh1g18 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 868
Score = 109 bits (263), Expect = 4e-22
Identities = 115/473 (24%), Positives = 197/473 (41%), Gaps = 40/473 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E M V V + D NDN+P F+ S + E + +G AVDPD+G N +
Sbjct: 92 ENPMELYRVTVDIQDINDNSPAFLKSKI-EQEISELVLIGARFPLESAVDPDVGVNALQK 150
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y LQ T + + + + V SP+ + H+L + A D +
Sbjct: 151 YTLQPTDHFKLNVQNAEDGSKNVEIVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHIN 210
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
++ ++V + P F + Y+ + N T V ++ DA E S+ + +
Sbjct: 211 IIILDVN-------DNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADES---SHGIQYY 260
Query: 614 YEEGVP-----FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+E P F+++ SG + V + + + A +++ L+ + + V+D
Sbjct: 261 FEHATPTVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKA-KDHGGLTDSSEIIIDVID 319
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
VND + + + S + ++ + G I I N+ + + I
Sbjct: 320 VNDNKPKITIMSFSSAVS--EDAAPGTVIAMI---NVQDLDSGDNSKISCSIDLNSPFKI 374
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVF 787
++ + T LDRE+ Y +T+ A + +S I + + I D ND+ P F
Sbjct: 375 ISSLTNYYNLVTDSELDREQTAEYNITITAVDGGNPPLSVKEI--LNLKISDVNDHAPQF 432
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEM---FDVDE 841
+Y FI EN+ T I +KA D D G NA Y L G + ++
Sbjct: 433 VQESYNAFIAENNPPSTTIL---TVKAEDMDWGPNAKVSYFLIDADLNGAPLASYISINS 489
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+GVV + S D E+ +K+ + A+D G LSS L I+I D+NDN P+
Sbjct: 490 ESGVV-YAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNAPQ 541
Score = 97.5 bits (232), Expect = 2e-18
Identities = 61/176 (34%), Positives = 97/176 (55%), Gaps = 11/176 (6%)
Query: 733 AEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
AEDG+ I PLDREK++ + + ++ F+ G + + I I D NDN PVF
Sbjct: 166 AEDGSKNVEIVLHSPLDREKKNHHSL-ILTAFDGGKPQRSATLHINIIILDVNDNAPVFS 224
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG--KEMFDVDENTGVV 846
++Y+ I+EN+ T + + ATDADE ++ + Y K +F +D ++G V
Sbjct: 225 QSSYKTSIVENAPKSTVVIR---VSATDADESSHGIQYYFEHATPTVKALFSIDADSGDV 281
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
K G +D EK +K+ + A+D GGL+ +E+II + D NDNKP+ + +S V
Sbjct: 282 KVTGQ-IDYEKHKQFKIKVKAKDHGGLTDSSEIIIDVIDVNDNKPKITIMSFSSAV 336
Score = 84.2 bits (199), Expect = 2e-14
Identities = 58/169 (34%), Positives = 87/169 (51%), Gaps = 6/169 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D+GV A +Y L + KL ++ +GS +E L + + N L + A
Sbjct: 138 AVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNVEIVLHSPLDRE-KKNHHSLILTAF 196
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++A + I +LD+NDN P F Y SIVEN P V++V ATD D+ +G
Sbjct: 197 DGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHG 256
Query: 340 -EFTYQLDDP--KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
++ ++ P K FSID SG + V Q +D E H ++KV AK+
Sbjct: 257 IQYYFEHATPTVKALFSIDADSGDVKVTGQ--IDYEKHKQFKIKVKAKD 303
Score = 79.4 bits (187), Expect = 7e-13
Identities = 115/475 (24%), Positives = 192/475 (40%), Gaps = 41/475 (8%)
Query: 925 NKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
N LDV+ P+F I EN P T +I+++A D D +G I+Y F +
Sbjct: 210 NIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHG-IQYYFE---HAT 265
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFV 1035
P+ VK F I+ G V V + E +F++ + A D G L D+ + + V
Sbjct: 266 PT--------VKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGGLTDSSEIIIDV 317
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE- 1094
DVND+ P ++ V E V+ ++ D D G N+ ++ I D + PF+
Sbjct: 318 IDVNDNKPKITIMSFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSI---DLNSPFKI 374
Query: 1095 ISPLTGV--LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
IS LT L + ELDRE +Y +T+ A D G DVND++P+F
Sbjct: 375 ISSLTNYYNLVTDSELDREQTAEYNITITAVDGG-NPPLSVKEILNLKISDVNDHAPQFV 433
Query: 1153 --AFDELLEWKHPEADELSNHNFESVMMIPVYKAT---IE---ENAPIGTTVAKVFANDT 1204
+++ + +P + + E + P K + I+ AP+ + ++ +
Sbjct: 434 QESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGAPLASYISINSESGV 493
Query: 1205 DFIGNG-NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
+ + L S + Q+ G P LSS L + + D D PV
Sbjct: 494 VYAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNAPQVLYPVQTGASVV 553
Query: 1264 LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRS-PD 1322
EI LV+ + ++ + + R F + +NG + VR D
Sbjct: 554 AEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAADRALFEVGLQNGEIRTVRQVTD 613
Query: 1323 RE-VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDN 1376
++ VK V+V Q + + VA+ E ++++ K NDN
Sbjct: 614 KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEF--TDFTHEKQYNDN 666
Score = 73.7 bits (173), Expect = 3e-11
Identities = 82/336 (24%), Positives = 146/336 (43%), Gaps = 25/336 (7%)
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L ++A DGG + + + + + DVND+ PVF ++ Y ++ E V+ +V ATDA
Sbjct: 191 LILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDA 250
Query: 1073 DFGQNANLTYFIQPSDT-DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
D + YF + T F I +G + V G++D E ++ + V A+D+G
Sbjct: 251 DESSHGIQYYFEHATPTVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHG---GL 307
Query: 1132 XXXXXXXXXXXDVNDNSPK--FYAFDELLEWKHPEADELSNHNFESVMMIPVYK--ATIE 1187
DVNDN PK +F + ++ N + + K +I+
Sbjct: 308 TDSSEIIIDVIDVNDNKPKITIMSFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSID 367
Query: 1188 ENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADV 1245
N+P I +++ + TD + Y++ + G P LS IL + ++DV
Sbjct: 368 LNSPFKIISSLTNYYNLVTDSELDREQTAEYNI--TITAVDGGNPPLSVKEILNLKISDV 425
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE---NFKMRYYILNE--NDT 1300
D P F+ Y I EN N P + E + N K+ Y++++ N
Sbjct: 426 NDHA-----PQFVQESYNAFIAEN-NPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGA 479
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ I+ +G +Y +S D E ++++ V+A+
Sbjct: 480 PLASYISINSESGVVYAEKSFDYEQLKSFKMQVKAQ 515
Score = 67.3 bits (157), Expect = 3e-09
Identities = 73/252 (28%), Positives = 108/252 (42%), Gaps = 24/252 (9%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G + + +DRE+ F+ + + +Y+VT+ I+D NDN P F + E
Sbjct: 61 ENGHLVIKNKIDREELCGEISACSVSFDVILENPMELYRVTVDIQDINDNSPAFLKSKIE 120
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKFI 849
I E IG +++ A D D G NAL YTL +V D + V +
Sbjct: 121 QEISELVLIGARFPLES---AVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNVEIVL 177
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
LDREKK + L L A D G S+ + I+I D NDN P F+Q + +
Sbjct: 178 HSPLDREKKNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSI----- 232
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG---LNG 964
N +I V + D G + P T+ L ++D DSG + G
Sbjct: 233 -VENAPKSTVVIRVSATD---ADESSHGIQYYFEHATP---TVKALFSIDADSGDVKVTG 285
Query: 965 QIRYEFNSEVYI 976
QI YE + + I
Sbjct: 286 QIDYEKHKQFKI 297
Score = 67.3 bits (157), Expect = 3e-09
Identities = 79/334 (23%), Positives = 130/334 (38%), Gaps = 25/334 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L G Q SA L + + I DVNDN P+F + Y ++ E P
Sbjct: 193 LTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADE 252
Query: 127 SLT-IPLTVPRGLTIFKDIRAFDRDKPNTP-NSDVHYSI-----VSGNDDGHFALESSHK 179
S I K + + D D + + Y + H L S +
Sbjct: 253 SSHGIQYYFEHATPTVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGGLTDSSE 312
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAID-QDLGVGATLRYELISG 238
++ + D D + ++ IM+ + ++ I I+ QDL G +
Sbjct: 313 IIIDV-----IDVNDNKPKITIMSFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSID 367
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+ + S+ L + +LD E + N + V NP + + + +++ D
Sbjct: 368 LNSPFKIISSLTNYYNLVTDSELDREQTAEYNITITAVDGG---NPPLSVKEILNLKISD 424
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP--KGA----- 351
+ND+ P+F + YN I EN P ++L V A D D G N + +Y L D GA
Sbjct: 425 VNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGAPLASY 484
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
SI+ SG V + D E S +M+V A++
Sbjct: 485 ISINSESG--VVYAEKSFDYEQLKSFKMQVKAQD 516
Score = 66.9 bits (156), Expect = 4e-09
Identities = 108/402 (26%), Positives = 170/402 (42%), Gaps = 56/402 (13%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A+ G + +D EK +++ V A+ + G+ + ++ I + D NDN P ++
Sbjct: 276 ADSGDVKVTGQIDYEKHKQFKIKVKAKDHGGLTDSS---EIIIDVIDVNDNKPKITIMSF 332
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN-TGVVKFIGD 851
+ E++ GT I M N+ D D G N+ ++ + F + + T + D
Sbjct: 333 SSAVSEDAAPGTVIAMINV---QDLDSGDNSKISCSI--DLNSPFKIISSLTNYYNLVTD 387
Query: 852 S-LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
S LDRE+ Y +++ A D G LS + L + I D ND+ P+F Q N+ +
Sbjct: 388 SELDREQTAEYNITITAVDGGNPPLSVKEILNLKISDVNDHAPQFVQESYNAFI------ 441
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ--I 966
N TI+ VK A D+D GP N + +I D+ LNG
Sbjct: 442 AENNPPSTTILTVK-----AEDMD-WGP------NAKVSYFLI-------DADLNGAPLA 482
Query: 967 RY-EFNSEVYIPPSKLSADALEVKRY-FVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
Y NSE + ++ S D ++K + + + G S P S LNI D
Sbjct: 483 SYISINSESGVVYAEKSFDYEQLKSFKMQVKAQDG-----GSPPLSSNVTLNIIIQD--- 534
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
NDN ++ V V + V A ++ KV A D D GQNA L+Y +
Sbjct: 535 QNDNAPQVLY--PVQTGASVVAEI-----VPRAADVGYLVTKVVAVDVDSGQNAWLSYKL 587
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
Q + FE+ G + ++ + K LTVV DNG
Sbjct: 588 QKAADRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNG 629
Score = 52.8 bits (121), Expect = 7e-05
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 19/167 (11%)
Query: 218 IHAIDQDLGVGATLRYELISG--NDRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTF 272
+ A D D G A + Y LI N L S S+N G ++ EK D + Q +F
Sbjct: 454 VKAEDMDWGPNAKVSYFLIDADLNGAPLASYISINSESGVVYAEKSFDYE-----QLKSF 508
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN----GFSVL 326
+QV+A +P ++ + I + D NDN P+ + V + E +P G+ V
Sbjct: 509 KMQVKAQDGGSPPLSSNVTLNIIIQDQNDNAPQVLYPVQTGASVVAEIVPRAADVGYLVT 568
Query: 327 QVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVLD 370
+V+A D D G+N +Y+L + F + ++G + TVR T D
Sbjct: 569 KVVAVDVDSGQNAWLSYKLQKAADRALFEVGLQNGEIRTVRQVTDKD 615
Score = 47.2 bits (107), Expect = 0.003
Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 24/224 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ IPE + +G+ + + ALDL G + + V+ +AD+ E Y +++
Sbjct: 14 YSIPEEMQVGSFVGNI-ALDL--GFEPKRLVSGKARVF------TADSSE---YIGLDKE 61
Query: 998 HGHVIVARSLPPESEFRLNISALDGG------NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+GH+++ + E E ISA N + V V ++D+ND+ P F K+
Sbjct: 62 NGHLVIKNKIDRE-ELCGEISACSVSFDVILENPMELYRVTVDIQDINDNSPAFLKSKIE 120
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD----TDLPFEISPLTGVLSVNGE 1107
+ E A D D G NA Y +QP+D E + ++
Sbjct: 121 QEISELVLIGARFPLESAVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNVEIVLHSP 180
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE ++ + L + A D G DVNDN+P F
Sbjct: 181 LDREKKNHHSLILTAFDGG-KPQRSATLHINIIILDVNDNAPVF 223
Score = 43.2 bits (97), Expect = 0.056
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 6/122 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V + + + D NDN P V P +++ + A VG ++ KV AVD D GQN
Sbjct: 522 LSSNVTLNIIIQDQNDNAPQVLYPVQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNA 581
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ Y LQ+ ++ + N TV V + ++ + + VE + QP+ + ++
Sbjct: 582 WLSYKLQKAADRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINV 641
Query: 553 AV 554
AV
Sbjct: 642 AV 643
>UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12;
Clupeocephala|Rep: Protocadherin 2A37 - Fugu rubripes
(Japanese pufferfish) (Takifugu rubripes)
Length = 1013
Score = 109 bits (263), Expect = 4e-22
Identities = 128/512 (25%), Positives = 207/512 (40%), Gaps = 36/512 (7%)
Query: 426 GTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV 485
GT + N+E E + NVEV +LD NDN P F P + Y+ + +A GT A
Sbjct: 103 GTCSLNLEVVLENPLDVHNVEVEILDVNDNAPQF-PRDEYQLEVSESALTGTRFHIEGAQ 161
Query: 486 DPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQP 542
D D G N + Y L R +LT+ S + + N + + P L H L + A D
Sbjct: 162 DADDGSNSVKQYRLSRNDHLTLDSVKQFSNNKHIELILKKPFDRELMPSHELILTAID-- 219
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
+ +R A + + + + P F + Y+ + N G V ++ D E
Sbjct: 220 -GGTPQRSGTARINVRILDA----NDNAPVFGSSVYKVKLSENSPKGALVIKLNAADIDE 274
Query: 603 --QNDVSYDLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLS 657
DV Y E V F+++ +G I V +++ Y+ A+ + A ++
Sbjct: 275 GSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPVA 334
Query: 658 IVTNATVHVVDVNDE-RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
V ++DVND ++L SP V+E++ + + N +G
Sbjct: 335 ANCKVVVDILDVNDNVPEIVLSSLSSP----VREDARADTVVALISVNDRD---SGQNKQ 387
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
L + TI T LDRE Y +TV A + G + +
Sbjct: 388 VTLEIGPNLPFAIKSFRNHYTIVTSAFLDRETIKSYNVTVSA-VDGGTPPLSSQMSFMVD 446
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D NDNPP FE +Y ++ EN+ G + +++ATDAD NA YT+ +
Sbjct: 447 VADVNDNPPRFEQTSYTVYVTENNAPGASL---CVVRATDADAAENARITYTVISDNNYG 503
Query: 837 FDVDENTGVVKFIGD-----SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
V + G+ + D EK + + A+D G LS + + I D+ND+
Sbjct: 504 IPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPPLSRVVTVYLYIMDQNDH 563
Query: 890 KPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
P+ N + K N AG + +V
Sbjct: 564 VPKIFYPPTNGSLTTEMLMK-NAEAGVLVSKV 594
Score = 99.5 bits (237), Expect = 6e-19
Identities = 112/456 (24%), Positives = 198/456 (43%), Gaps = 35/456 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LDANDN PVF S++Y+ + N+ G ++ K+ A D D G NG V Y +
Sbjct: 231 INVRILDANDNAPVF-GSSVYKVKLSENSPKGALVIKLNAADIDEGSNGDVFYSFSSYTP 289
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F ++ +TG + V + E + ++++A D+ P + V ++V
Sbjct: 290 ERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDV--- 346
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
++P+ + + V + T V I VND + L G +PFA+
Sbjct: 347 ----NDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTLEIG--PNLPFAI 400
Query: 623 EERSGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
+ T+V L R Y+ A+ LS + V V DVND +
Sbjct: 401 KSFRNHYTIVTSAFLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQT 460
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ--DVTDDIAIAED-G 736
+++ ++ + N+ GA++ + T+ + N + N V ++I + G
Sbjct: 461 SYT--VYVTENNAPGASLCVVRATDADAA-ENARITYTVISDNNYGIPVASYVSIKPNTG 517
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG-- 794
+ + D EK + V A+ N GV + + V +YI D+ND+ P + G
Sbjct: 518 EAYALRAFDFEKLREFHFQVKAQDN-GVPPLSRVVTVYLYIMDQNDHVPKIFYPPTNGSL 576
Query: 795 ---FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDENTGVVKFI 849
+M+N++ G + + A D D G NA MYTL ++F V E TG ++
Sbjct: 577 TTEMLMKNAEAGVLVSK---VVAWDGDAGQNAWLMYTLKQTNTDLDLFKVHEYTGEIRTT 633
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
++ + + L+++ RD G LS+ A L I +
Sbjct: 634 RHVIE-DNSTSFVLTVLVRDHGLPPLSTTATLHIHV 668
Score = 85.4 bits (202), Expect = 1e-14
Identities = 69/218 (31%), Positives = 98/218 (44%), Gaps = 20/218 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G +IKLNA D+D G NG + Y F+S Y P V++ F ++ G
Sbjct: 254 LSENSPKGALVIKLNAADIDEGSNGDVFYSFSS--YTPE--------RVRQMFSLDTDTG 303
Query: 1000 HVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V ++ E + + + I A+D G + N V V + DVND+ P + + V
Sbjct: 304 EIRVKNNIDYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVR 363
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDRETE 1113
E V+ + D D GQN +T I P +LPF I + + LDRET
Sbjct: 364 EDARADTVVALISVNDRDSGQNKQVTLEIGP---NLPFAIKSFRNHYTIVTSAFLDRETI 420
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y +TV A D G DVNDN P+F
Sbjct: 421 KSYNVTVSAVDGG-TPPLSSQMSFMVDVADVNDNPPRF 457
Score = 81.0 bits (191), Expect = 2e-13
Identities = 76/302 (25%), Positives = 139/302 (46%), Gaps = 34/302 (11%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-------NATVHVVDVNDE 672
FA+ ++G +TV D + R + +F + NL +V N V ++DVND
Sbjct: 78 FAINHKNGKLTVSDRIDR--ETICEFTGTC---SLNLEVVLENPLDVHNVEVEILDVNDN 132
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVT-DDI 730
P + E S A G FH + +G+ +V+ + ++ +T D +
Sbjct: 133 ------APQFPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDHLTLDSV 186
Query: 731 AIAEDGT---IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ + +KP DRE + + ++ + G +G ++ + I D NDN PVF
Sbjct: 187 KQFSNNKHIELILKKPFDRELMPSHEL-ILTAIDGGTPQRSGTARINVRILDANDNAPVF 245
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENT 843
+ Y+ + ENS G + + A D DEG+N Y+ ++MF +D +T
Sbjct: 246 GSSVYKVKLSENSPKGALVIK---LNAADIDEGSNGDVFYSFSSYTPERVRQMFSLDTDT 302
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSK 901
G ++ + +++D E+ Y++ + A D G +++ ++++ I D NDN PE +S
Sbjct: 303 GEIR-VKNNIDYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSP 361
Query: 902 VR 903
VR
Sbjct: 362 VR 363
Score = 71.7 bits (168), Expect = 1e-10
Identities = 102/416 (24%), Positives = 169/416 (40%), Gaps = 39/416 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ GT A D D G N +Y + + L+ D+ VK++ N +H
Sbjct: 145 VSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDH-----LTLDS--VKQFS--NNKHI 195
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
+I+ + E L ++A+DGG + + R+ V+ D ND+ PVF + Y +
Sbjct: 196 ELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLS 255
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRET 1112
E ++ K++A D D G N ++ Y P F + TG + V +D E
Sbjct: 256 ENSPKGALVIKLNAADIDEGSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEE 315
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ Y + + A D G DVNDN P+ L P ++
Sbjct: 316 TNSYEMYIQAMDKG-PAPVAANCKVVVDILDVNDNVPEIV----LSSLSSPVREDARADT 370
Query: 1173 FESVMMI-----PVYKATIEENAPIGTTVAKVFANDTDFIGNG--NGLILYSLPQRKNQQ 1225
+++ + K E P K F N + + + + S +
Sbjct: 371 VVALISVNDRDSGQNKQVTLEIGPNLPFAIKSFRNHYTIVTSAFLDRETIKSYNVTVSAV 430
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP-VELVSLNLT-- 1282
+ G P LSS MV VADV D + P F Y + + EN NAP L + T
Sbjct: 431 DGGTPPLSSQMSFMVDVADVND-----NPPRFEQTSYTVYVTEN-NAPGASLCVVRATDA 484
Query: 1283 EHYENFKMRYYILNENDTDIR-RTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ EN ++ Y ++++N+ I ++V I P G Y +R+ D E + V+A+
Sbjct: 485 DAAENARITYTVISDNNYGIPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQ 540
Score = 71.7 bits (168), Expect = 1e-10
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + +Y L + L S+ + + +E L + L + ++ + A
Sbjct: 160 AQDADDGSNSVKQYRLSRNDHLTLDSVKQFSNNKHIELILKKPFDRELMPSHELI-LTAI 218
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ AR+ + +LD NDN P F Y + + EN P G V+++ A D D+G NG
Sbjct: 219 DGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLSENSPKGALVIKLNAADIDEGSNG 278
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+ Y + + FS+D +G + V+N +D E +S M + A + P+ V
Sbjct: 279 DVFYSFSSYTPERVRQMFSLDTDTGEIRVKNN--IDYEETNSYEMYIQAMDKGPAPV 333
Score = 64.1 bits (149), Expect = 3e-08
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 18/219 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+++V N +Q + EN G ++ + A D D+ N +I Y S+
Sbjct: 444 MVDVADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITYTVISD---- 499
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRV 1033
+ + V Y I G R+ E EF + A D G L+ ++V +
Sbjct: 500 ----NNYGIPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPPLSRVVTVYL 555
Query: 1034 FVKDVNDHFP--VFKKTWYNFNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSD 1088
++ D NDH P + T + E ++ KV A D D GQNA L Y ++ ++
Sbjct: 556 YIMDQNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAWLMYTLKQTN 615
Query: 1089 TDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
TDL F++ TG + + + ++LTV+ RD+G
Sbjct: 616 TDLDLFKVHEYTGEIRTTRHVIEDNSTSFVLTVLVRDHG 654
Score = 62.5 bits (145), Expect = 9e-08
Identities = 43/169 (25%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y S R++FSLD+ G + ++ +D + + N++ +
Sbjct: 267 LNAADIDEGSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYE-----ETNSYEM 321
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+QA A +V +++LD+NDN+PE + + + E+ V + D+D
Sbjct: 322 YIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRD 381
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
G+N + T ++ P F+I T+ LDRE S + V A
Sbjct: 382 SGQNKQVTLEI-GPNLPFAIKSFRNHYTIVTSAFLDRETIKSYNVTVSA 429
Score = 62.1 bits (144), Expect = 1e-07
Identities = 67/286 (23%), Positives = 110/286 (38%), Gaps = 15/286 (5%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L I G Q S + V I D NDN P+F + Y V + E +P G A I
Sbjct: 215 LTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLSENSPKGALVIKLNAADIDE 274
Query: 127 SLTIPLTVPRGLTIFKDIR---AFDRDKPNTP-NSDVHYSIVSGNDDGHFALESSHKPVL 182
+ + +R + D D +++ Y + + A++ PV
Sbjct: 275 GSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPVA 334
Query: 183 LLRKVLD--YDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELIS 237
KV+ D D ++V+ + + ++ + I D+D G + E+
Sbjct: 335 ANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTLEI-- 392
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
F++ S + LD E ++ + V A P ++Q +++
Sbjct: 393 -GPNLPFAIKSFRNHYTIVTSAFLDRE---TIKSYNVTVSAVDGGTPPLSSQMSFMVDVA 448
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
D+NDN P FE Y + + EN G S+ V ATD D EN TY
Sbjct: 449 DVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITY 494
Score = 60.9 bits (141), Expect = 3e-07
Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 24/222 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ T + ++ D DSG N Q+ E + +K + H
Sbjct: 362 VREDARADTVVALISVNDRDSGQNKQVTLEIGPNL----------PFAIKSF----RNHY 407
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ + L E+ + + +SA+DGG L+ +S V V DVND+ P F++T Y V
Sbjct: 408 TIVTSAFLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVT 467
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP----FEISPLTGVLSVNGELDR 1110
E L V ATDAD +NA +TY I ++ +P I P TG D
Sbjct: 468 ENNAPGASLCVVRATDADAAENARITYTVISDNNYGIPVASYVSIKPNTGEAYALRAFDF 527
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
E ++ V A+DNG D ND+ PK +
Sbjct: 528 EKLREFHFQVKAQDNG-VPPLSRVVTVYLYIMDQNDHVPKIF 568
Score = 55.2 bits (127), Expect = 1e-05
Identities = 44/143 (30%), Positives = 67/143 (46%), Gaps = 9/143 (6%)
Query: 208 IHKEILFPEPIHAIDQDLGVG----ATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLD 262
I +E+ P+ I QDLG+ + R + S G R+ F+++ NG L + +D +
Sbjct: 37 IPEELENGAPVGDIVQDLGLDPRKLSARRIRVTSDGTHRRYFAINHKNGKLTVSDRIDRE 96
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG 322
T L ++ L NPL VE+E+LD+NDN P+F D Y + + E+ G
Sbjct: 97 TICEF-TGTCSLNLEVV-LENPLDVHN--VEVEILDVNDNAPQFPRDEYQLEVSESALTG 152
Query: 323 FSVLQVMATDKDQGENGEFTYQL 345
A D D G N Y+L
Sbjct: 153 TRFHIEGAQDADDGSNSVKQYRL 175
Score = 52.4 bits (120), Expect = 9e-05
Identities = 58/205 (28%), Positives = 86/205 (41%), Gaps = 18/205 (8%)
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEV------KRYFVINERHGHVIVARSLPPES--EFR 1014
NG + ++ + P KLSA + V +RYF IN ++G + V+ + E+ EF
Sbjct: 43 NGAPVGDIVQDLGLDPRKLSARRIRVTSDGTHRRYFAINHKNGKLTVSDRIDRETICEFT 102
Query: 1015 ----LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
LN+ + L D +V V + DVND+ P F + Y V E+ T A
Sbjct: 103 GTCSLNLEVVLENPL-DVHNVEVEILDVNDNAPQFPRDEYQLEVSESALTGTRFHIEGAQ 161
Query: 1071 DADFGQNANLTYFIQPSD---TDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNG 1126
DAD G N+ Y + +D D + S + L + DRE + L + A D G
Sbjct: 162 DADDGSNSVKQYRLSRNDHLTLDSVKQFSNNKHIELILKKPFDRELMPSHELILTAIDGG 221
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKF 1151
D NDN+P F
Sbjct: 222 -TPQRSGTARINVRILDANDNAPVF 245
Score = 40.7 bits (91), Expect = 0.30
Identities = 54/234 (23%), Positives = 95/234 (40%), Gaps = 10/234 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S ++ V + D NDN P F ++ + ++NA G + V+A D D +N + Y
Sbjct: 437 LSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAP-GASLCVVRATDADAAENARITYT 495
Query: 499 LQRTSN--LTITSPFKINPNTGTVSVAESPILEG-RHALF-VEASDQPANPSERRYSLAV 554
+ +N + + S I PNTG + E R F V+A D P R ++ +
Sbjct: 496 VISDNNYGIPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPPLSRVVTVYL 555
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH 612
++ + K P G+ + N G V ++ DA + + Y L
Sbjct: 556 YIMD--QNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAWLMYTLKQ 613
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
+ F V E +G I + N + V ++++ + T AT+H+
Sbjct: 614 TNTDLDLFKVHEYTGEIRTTRHVIEDNSTSFVL-TVLVRDHGLPPLSTTATLHI 666
>UniRef50_Q9UII7 Cluster: E-cadherin; n=5; Catarrhini|Rep: E-cadherin
- Homo sapiens (Human)
Length = 901
Score = 109 bits (263), Expect = 4e-22
Identities = 132/473 (27%), Positives = 197/473 (41%), Gaps = 55/473 (11%)
Query: 701 FHTNMSSIYGNGT--GNVRFLIANQQDVTDDIAI----AEDGTIFTQKPLDREKRDVYRM 754
F N+ I N G V + I Q T + + E G + +PLDRE+ Y +
Sbjct: 171 FPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTL 230
Query: 755 TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
A + G + ++ I + D+NDN P F ++G +ME + GT + M+ + A
Sbjct: 231 FSHAVSSNGNAVEDPM-EILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSV-ME--VTA 286
Query: 815 TDADEGT---NALFMYTLFGE-----GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
TDAD+ NA YT+ + K MF ++ NTGV+ + LDRE Y L +
Sbjct: 287 TDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQ 346
Query: 867 ARDT--GGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV--K 922
A D GLS+ A +I + D NDN P FN +V + + T T +
Sbjct: 347 AADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNT 406
Query: 923 PKNKFALDV-DQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
P + + + G F++ N P+ I A DL N + +S Y P L
Sbjct: 407 PAWEAVYTILNDDGGQFVVTTN-PVNNDGILKTAKDLARCRN----WHPHSCSY--PCPL 459
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
D E K+ +++ HV V +P F ++++ +V V V DVN+
Sbjct: 460 GLD-FEAKQQYIL-----HVAVTNVVP----FEVSLT-------TSTATVTVDVLDVNE- 501
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
P+F V E + + A + D +TY I DT EI+P TG
Sbjct: 502 APIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW-RDTANWLEINPDTGA 560
Query: 1102 LSVNGELDRE-----TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+S ELDRE Y ++A DNG DVNDN+P
Sbjct: 561 ISTRAELDREDFEHVKNSTYTALIIATDNG-SPVATGTGTLLLILSDVNDNAP 612
Score = 54.4 bits (125), Expect = 2e-05
Identities = 53/172 (30%), Positives = 74/172 (43%), Gaps = 13/172 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISAL--DGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F+I G + V L E + + L A+ +G + D + + + V D ND+ P F +
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFG---QNANLTYFIQPSDTDLP----FEISPLTG 1100
+ +V E + +V ATDAD NA + Y I D +LP F I+ TG
Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324
Query: 1101 VLS-VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V+S V LDRE+ Y L V A D D NDN P F
Sbjct: 325 VISVVTTGLDRESFPTYTLVVQAADL-QGEGLSTTATAVITVTDTNDNPPIF 375
Score = 48.0 bits (109), Expect = 0.002
Identities = 96/386 (24%), Positives = 153/386 (39%), Gaps = 50/386 (12%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD---LGQNGMVLYD- 498
+ + +T+ D NDN P F +++ S+ A GT + +V A D D N + Y
Sbjct: 246 MEILITVTDQNDNKPEFT-QEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI 304
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVV 555
L + L + F IN NTG +SV + + + L V+A+D E + A
Sbjct: 305 LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADL---QGEGLSTTATA 361
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY- 614
I VT T N P F Y+ V N + ++V DA N +++ ++
Sbjct: 362 VITVT-DTNDNP---PIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTIL 416
Query: 615 -EEGVPFAVE----ERSGVITVVDDLSR----------YNRPM-YDFEAVALQENANLSI 658
++G F V G++ DL+R Y P+ DFE A Q+
Sbjct: 417 NDDGGQFVVTTNPVNNDGILKTAKDLARCRNWHPHSCSYPCPLGLDFE--AKQQYILHVA 474
Query: 659 VTNATVHVVDVNDERGV----LLKGAHSPIIFHVK---ENSAGAAIGQIFHTNMSSIYGN 711
VTN V + +L +PI + E S +GQ T+ ++ +
Sbjct: 475 VTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEI-TSYTAQEPD 533
Query: 712 GTGNVRFLIANQQDVTDDIAIAED-GTIFTQKPLDRE-----KRDVYRMTVIAEFNKGVI 765
+ +D + + I D G I T+ LDRE K Y +IA N +
Sbjct: 534 TFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPV 593
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G + + + D NDN P+ E T
Sbjct: 594 A-TGTGTLLLILSDVNDNAPIPEPRT 618
Score = 47.6 bits (108), Expect = 0.003
Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
T+ L A N + I + D NDN PEF + + S++E G SV++V A
Sbjct: 227 TYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTA 286
Query: 331 TDKDQGENG-----EFTYQLDDP----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
TD D N +T DP K F+I+ +G ++V T LDRE+ + + V
Sbjct: 287 TDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVT-TGLDRESFPTYTLVV 345
Query: 382 YAKETNPSVVGTFA 395
A + + T A
Sbjct: 346 QAADLQGEGLSTTA 359
Score = 46.0 bits (104), Expect = 0.008
Identities = 54/231 (23%), Positives = 88/231 (38%), Gaps = 15/231 (6%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
F +E +G + V + L R Y + A+ N N + + V D ND + +
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI----AE 734
+ ++ G ++ ++ T+ + + I +Q D +
Sbjct: 265 EVFKGSV--MEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRN 322
Query: 735 DGTI-FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I LDRE Y + V A +G V I + D NDNPP+F TY+
Sbjct: 323 TGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAV-ITVTDTNDNPPIFNPTTYK 381
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALF--MYTLFGEGKEMFDVDEN 842
G + EN + I +K TDAD + +YT+ + F V N
Sbjct: 382 GQVPEN-EANVVI---TTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTN 428
>UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor
(Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1).; n=2;
Xenopus tropicalis|Rep: Protocadherin-16 precursor
(Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1). -
Xenopus tropicalis
Length = 2375
Score = 109 bits (262), Expect = 6e-22
Identities = 130/474 (27%), Positives = 204/474 (43%), Gaps = 41/474 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+Q +SF + ++LLD NDN P F ++ ++ G+ + +V A DPD G NG V
Sbjct: 1226 QQHLSFATLTISLLDLNDNAPRFQLPRYTAYTQEAQPD-GSPLIQVLAEDPDQGLNGQVT 1284
Query: 497 YDLQRTSNLTITSPFKINPNTG---TVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
Y ++ + F+I+P TG T ++ + I H L V A+D+ + P S A
Sbjct: 1285 YSFDQSQ--AMKDLFRIDPQTGAITTAAILDREIWSQAH-LVVIATDRGSPPLT---SSA 1338
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL-H 612
+T+ VT N P P E V + IG+ + Q+ ND +SY LL
Sbjct: 1339 TLTVLVT-DVNDNSPTTP----LQLELSVPEDAVIGSEILQVTGNDVDSGPALSYTLLVD 1393
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G EG F + G I + L +R Y V + +L+ T+ + DVND
Sbjct: 1394 GAMEGA-FTMLRYGGQIWLSRQLDYEDRKSYSL-TVQTSDGKHLT-HAELTLTLQDVNDN 1450
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
K + I ++ +AG + + T+ S G V + + + I
Sbjct: 1451 SPEFGKSLYQVSI--LEHAAAGTPLFTVRATDRDS---GDNGRVSYRVLSPVGGAFHIH- 1504
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++GT+F K ++ + + ++ + G S A + V + D ND+ P F + Y
Sbjct: 1505 PDNGTLFANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQY 1564
Query: 793 EGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYT-LFGEGKEMFDVDEN----TGVV 846
+ E+ +G+ + I++ TDAD NA YT L G F V G
Sbjct: 1565 SASVPEDLPLGSTVL---ILEVTDADFTQENAALDYTILSGNTDNAFQVQSGMRFWNGRF 1621
Query: 847 KFIG-----DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ IG DSLD E Y L+L A D G S ++I + D NDN P F
Sbjct: 1622 QQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLDINDNPPVF 1675
Score = 103 bits (248), Expect = 3e-20
Identities = 122/488 (25%), Positives = 208/488 (42%), Gaps = 48/488 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ D + ++ + +TL D NDN+P F S LY+ S+ +A GT + V+A D D G
Sbjct: 1427 VQTSDGKHLTHAELTLTLQDVNDNSPEFGKS-LYQVSILEHAAAGTPLFTVRATDRDSGD 1485
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL---FVEASDQPANPSER 548
NG V Y + + F I+P+ GT+ + L+ + L VEA D +PS
Sbjct: 1486 NGRVSYRVLSP----VGGAFHIHPDNGTLFANKLVELDPQSPLVDVLVEARDH-GSPSLA 1540
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVS 607
SL V V + P F + Y V ++ +G++V + V DA F Q + +
Sbjct: 1541 --SLTTVQFLVVDANDHS----PTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQENAA 1594
Query: 608 --YDLLHGYEEGVPFAVE----------ERSGVITVVDDLSRYNRPMYDFEAVALQENA- 654
Y +L G + F V+ ++ G I + D L Y+ A
Sbjct: 1595 LDYTILSGNTDNA-FQVQSGMRFWNGRFQQIGSIILTDSLDFEAISFYNLTLGASDRGVP 1653
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
S ++V+D+ND V + +S ++ +E G+ + ++ + S G
Sbjct: 1654 QRSHSVPVLINVLDINDNPPVFPRPLYSVLLS--EEAPVGSEVLRVLAQDSDS---GSNG 1708
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
V + I + + G I + LDRE++ ++ + V+A +G + + VT
Sbjct: 1709 LVHYSITSGDESRLFQINEATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVT 1768
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--- 831
I + D NDN P F I EN T + I A D D G YT+
Sbjct: 1769 IEVRDINDNKPYFPVQILTTSIRENQPANTPLTK---IHAIDLDTGVYGQLFYTMLDLAV 1825
Query: 832 ------EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD 885
GK+MF V+ +G ++ S D E+ ++ + + A D G S+ + +++
Sbjct: 1826 AGSGMLMGKDMFVVNRTSGELR-SKQSFDYERIKVFNMVVKAMDAGNFSATVTVQVLVTG 1884
Query: 886 ENDNKPEF 893
E++ P F
Sbjct: 1885 EDEYNPVF 1892
Score = 97.9 bits (233), Expect = 2e-18
Identities = 88/320 (27%), Positives = 150/320 (46%), Gaps = 23/320 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQR 501
V++EV + D ND++P F P + + +A VG+ + +A D D G N V Y L R
Sbjct: 564 VHIEVEVQDRNDHSPAF-PEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLR 622
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ S F+++ TG + VA++ E + L VEASDQ N S++R + + +
Sbjct: 623 QDPGSPGSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFI 682
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIG-TSVGQIRVN-DAFEQNDVSYDLLHGYEEG 617
+ P F+ P W+ ++ +G T++ + + D + V Y L+ G +EG
Sbjct: 683 S----DRNDHAPQFI-TPLVVWLPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEG 737
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
F + SG +TVV L R Y+ VA+ + LS +V ++DVNDE
Sbjct: 738 -KFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSF 796
Query: 677 LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
K + V+EN G + ++ + +G V + + + D E
Sbjct: 797 EKPQYDA---QVQENQPVGTTVLRVVALDRDL---GQSGRVTYGGVSGDEFALD---PET 847
Query: 736 GTIFTQKPLDREKRDVYRMT 755
G + T+ PLDRE +++Y++T
Sbjct: 848 GVLTTKVPLDREAKELYKLT 867
Score = 96.3 bits (229), Expect = 6e-18
Identities = 132/480 (27%), Positives = 211/480 (43%), Gaps = 48/480 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNL-YEFSMK--SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V +T+LD NDN P F+ N E S++ K G I ++A DPD G+NG V Y L
Sbjct: 354 VHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENGTVTYSLAG 413
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV---TIE 558
T T + P V++A PI H++ + P PS + V +
Sbjct: 414 TGYKT--DRLVVAPLA--VALAPPPI----HSMPMHDFSPPTPPSWPPHVFNVTPFTAFQ 465
Query: 559 VTRGTK-GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
V ++ +K + + +P E + G+ +G + Y LL G
Sbjct: 466 VIPASRYPSKSNPSSLVLSPME-----GLAPGSLLGSLAPR--MPHGSRIYTLLDE-PHG 517
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE--NANLSIVTNATVHV-VDVNDERG 674
+ F V+ ++G I +V +L ++P + F V+++E A+L V VH+ V+V D
Sbjct: 518 I-FMVDGQTGSIFLVGELDFESQPRFSFR-VSVEEVREASLGYVPPHVVHIEVEVQDRND 575
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY-GNGTGN-VRFLIANQQDVTDDIAI 732
P+ V E+ A +G T +S + G G + VR+ + Q +
Sbjct: 576 HSPAFPEDPLTLVVPED---AHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTF 632
Query: 733 ---AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT--IYIEDENDNPPVF 787
AE G ++ + LDRE+ Y + V A +S VT ++I D ND+ P F
Sbjct: 633 RLDAETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQF 692
Query: 788 EHATYEGFIMENSKIG-TEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGV 845
++ E+ +G T I M A D D G N Y L G E F + ++G
Sbjct: 693 ITPLVV-WLPEDLPVGSTAIYM----VAQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGA 747
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+ + +LDRE Y L++VA D G LSS L + + D ND P F + + +++V+
Sbjct: 748 LTVVR-TLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQ 806
Score = 95.9 bits (228), Expect = 8e-18
Identities = 89/316 (28%), Positives = 138/316 (43%), Gaps = 43/316 (13%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D DLG + Y+L+ GND F L +G+L + + LD + + L V A
Sbjct: 715 AQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGALTVVRTLDRETTEG-----YNLTVVAM 769
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ + + LLD+ND P FE Y+ + EN P G +VL+V+A D+D G++G
Sbjct: 770 DHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSG 829
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQR 399
TY F++DP +G LT + LDREA ++Y N +V+G +
Sbjct: 830 RVTYG-GVSGDEFALDPETGVLTTK--VPLDREA-----KELYKLTGNNNVLGQWQTVLP 881
Query: 400 IAK-----------W-----RRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFV 443
+A W +PL +P E+T +V +G + L S
Sbjct: 882 VAPVPIGVALYIYIWGGGSLYLEPLSGMSPKERTVFVQATDLG---------EPPLSSTA 932
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+ V L + P F P E S+ N+ G+V+G A G G + Y +
Sbjct: 933 VLVVHLREEAPQGPRF-PQEAIEISLPENSPEGSVVGTATAAHTG-GSTGRISYSFLSGN 990
Query: 504 NLTITSPFKINPNTGT 519
+I+P TGT
Sbjct: 991 E---NGALRIHPTTGT 1003
Score = 89.0 bits (211), Expect = 9e-16
Identities = 150/649 (23%), Positives = 253/649 (38%), Gaps = 75/649 (11%)
Query: 515 PNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
P G ++VA++ +L+ RH L ++A Q + S A +TI + +
Sbjct: 1196 PPAGQITVAQAAMLDYEQNPRHKLVLQAETQ------QHLSFATLTISLL----DLNDNA 1245
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGV 628
P F Y + G+ + Q+ D + V+Y F ++ ++G
Sbjct: 1246 PRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTYSFDQSQAMKDLFRIDPQTGA 1305
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFH 687
IT L R +A + L+ TV V DVND +P+
Sbjct: 1306 ITTAAILDREIWSQAHLVVIATDRGSPPLTSSATLTVLVTDVNDNSPT------TPLQLE 1359
Query: 688 VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
+ +I + + + L+ + + + G I+ + LD E
Sbjct: 1360 LSVPEDAVIGSEILQVTGNDVDSGPALSYTLLVDGAMEGAFTM-LRYGGQIWLSRQLDYE 1418
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
R Y +TV K + ++T+ ++D NDN P F + Y+ I+E++ GT +
Sbjct: 1419 DRKSYSLTVQTSDGKHLTHA----ELTLTLQDVNDNSPEFGKSLYQVSILEHAAAGTPLF 1474
Query: 808 MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI-MYKLSLV 866
++ATD D G N Y + F + + G + F ++ + + + + +
Sbjct: 1475 T---VRATDRDSGDNGRVSYRVLSPVGGAFHIHPDNGTL-FANKLVELDPQSPLVDVLVE 1530
Query: 867 ARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK 924
ARD G L+S + ++ D ND+ P F+Q + ++ V + L T I+EV
Sbjct: 1531 ARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQYSASV--PEDLPLGSTV--LILEV--- 1583
Query: 925 NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
D D EN + TI+ N D + +R+ +N S + D
Sbjct: 1584 ----TDAD------FTQENAALDYTILSGNT-DNAFQVQSGMRF-WNGRFQQIGSIILTD 1631
Query: 985 ALEVKRYFVINERHGHVIVARSLPPES-EFRLNISALDGGNLNDNISVRVFVKDVNDHFP 1043
+L+ + N G R +P S + I+ LD +NDN P
Sbjct: 1632 SLDFEAISFYNLTLG--ASDRGVPQRSHSVPVLINVLD---INDNP-------------P 1673
Query: 1044 VFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
VF + Y+ + EEA VL +V A D+D G N + Y I D F+I+ TG +
Sbjct: 1674 VFPRPLYSVLLSEEAPVGSEVL-RVLAQDSDSGSNGLVHYSITSGDESRLFQINEATGAI 1732
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ LDRE + + L V+A D D+NDN P F
Sbjct: 1733 RLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYF 1781
Score = 85.4 bits (202), Expect = 1e-14
Identities = 102/390 (26%), Positives = 156/390 (40%), Gaps = 34/390 (8%)
Query: 449 LLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTIT 508
+ D NDN P F PS + ++S +G+VI + +A DPD G NG V Y+L +I
Sbjct: 55 ITDVNDNPPAF-PSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYELDSPGPFSID 113
Query: 509 SPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
++ TG +S + R+ + V ASD L V+ +E+ +
Sbjct: 114 GSGQLRA-TGLLS-------QERYDVRVLASDGGTPQLSSALELTVLLMELQKE------ 159
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGV 628
P + Y V + + Q+R L + V F++E SG
Sbjct: 160 --PACGASDYRVEVREGSPPLSRLLQVRAQPPGAGEGQLIYRLRPDADAVGFSIEADSGW 217
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
+ V L R +R Y +A + V V D ND L +
Sbjct: 218 LYVRGALDRESREAYVLAVLASAGPGTRTATCTVRVRVTDENDNSPRL---SEERFFLSA 274
Query: 689 KENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE 747
EN G +G++ T+ + G V + + + +D G + T++ LDRE
Sbjct: 275 TENRPPGETVGRVSATDRDA---GPNGRVSYRLPPLE--SDFHINPHTGELSTRRVLDRE 329
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI----MENSKIG 803
+ Y++ VIA+ + G + V I + DENDN P F H I ME K G
Sbjct: 330 LQATYQLLVIAQ-DGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSG 388
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEG 833
I ++A D DEG N Y+L G G
Sbjct: 389 MFIAS---LQAKDPDEGENGTVTYSLAGTG 415
Score = 85.0 bits (201), Expect = 1e-14
Identities = 89/318 (27%), Positives = 145/318 (45%), Gaps = 22/318 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+T+YI DVNDN P F +P+H T+ +P + IF P V L
Sbjct: 51 LTLYITDVNDNPPAF-PSPFH-TLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYELDSPG 108
Query: 143 --DIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDA-GDKEFQ 198
I + + S Y + V +D G L S+ + +LL ++ A G +++
Sbjct: 109 PFSIDGSGQLRATGLLSQERYDVRVLASDGGTPQLSSALELTVLLMELQKEPACGASDYR 168
Query: 199 LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKE 258
+ + + + + + A G G + Y L D FS+++ +G L++
Sbjct: 169 VEVREGSPPLSRLL----QVRAQPPGAGEGQLI-YRLRPDADAVGFSIEADSGWLYVRGA 223
Query: 259 LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN 318
LD ++ +VL V AS +TA V + + D NDN P + + +S EN
Sbjct: 224 LDRESRE-----AYVLAVLASA-GPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATEN 277
Query: 319 LPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLR 378
P G +V +V ATD+D G NG +Y+L + F I+P +G L+ R VLDRE ++ +
Sbjct: 278 RPPGETVGRVSATDRDAGPNGRVSYRLPPLESDFHINPHTGELSTRR--VLDRELQATYQ 335
Query: 379 MKVYAKETNP---SVVGT 393
+ V A++ SV GT
Sbjct: 336 LLVIAQDGGAPPRSVTGT 353
Score = 84.6 bits (200), Expect = 2e-14
Identities = 81/295 (27%), Positives = 127/295 (43%), Gaps = 36/295 (12%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS-GLNGQIRYEF-NSEVYI 976
+EV+ +N + + ++PE+ +G+++ A D D G N Q+RY +
Sbjct: 568 VEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGS 627
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPE-SEFRLNISALDGGNLNDNISVRVFV 1035
P S DA E +V + + L E S+ +N+S + +++ RVF+
Sbjct: 628 PGSTFRLDA-ETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQ----QRSTSVTARVFI 682
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
D NDH P F + E+ + V A D D G N + Y + + + F++
Sbjct: 683 SDRNDHAPQFITPLVVWLPEDLPVGSTAIYMV-AQDPDLGDNGKVGYQLVGGNDEGKFQL 741
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFD 1155
P +G L+V LDRET + Y LTVVA D+G DVND +P F
Sbjct: 742 HPSSGALTVVRTLDRETTEGYNLTVVAMDHG-SPRLSSTQTLSVSLLDVNDEAPSF---- 796
Query: 1156 ELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
+ P+ Y A ++EN P+GTTV +V A D D +G
Sbjct: 797 -----EKPQ-----------------YDAQVQENQPVGTTVLRVVALDRDLGQSG 829
Score = 82.2 bits (194), Expect = 1e-13
Identities = 102/396 (25%), Positives = 177/396 (44%), Gaps = 62/396 (15%)
Query: 734 EDGTIFTQKPLDREK--RDVYRMTV--IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+ G+IF LD E R +R++V + E + G + + + + ++D ND+ P F
Sbjct: 524 QTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVP-PHVVHIEVEVQDRNDHSPAFPE 582
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ E++ +G+ + +A+D D G N+ Y+L + D + F
Sbjct: 583 DPLTLVVPEDAHVGSSVFT---FQASDHDGPGPNSQVRYSLLRQ-------DPGSPGSTF 632
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
LD E ++Y + R+ E +++ + +D +Q R T
Sbjct: 633 ---RLDAETGVLYVAQALDRE------EVSSYLLVVEASDQAVNVSQ---------QRST 674
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIR 967
+ + + +N A + PL + +PE++P+G+T I + A D D G NG++
Sbjct: 675 SVTAR-----VFISDRNDHAPQF--ITPLVVWLPEDLPVGSTAIYMVAQDPDLGDNGKVG 727
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN- 1024
Y+ L E K F ++ G + V R+L E+ + L + A+D G+
Sbjct: 728 YQ-----------LVGGNDEGK--FQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSP 774
Query: 1025 -LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
L+ ++ V + DVND P F+K Y+ V+E Q + +V A D D GQ+ +TY
Sbjct: 775 RLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSGRVTYG 834
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
D F + P TGVL+ LDRE ++ Y LT
Sbjct: 835 GVSGD---EFALDPETGVLTTKVPLDREAKELYKLT 867
Score = 79.8 bits (188), Expect = 5e-13
Identities = 57/164 (34%), Positives = 82/164 (50%), Gaps = 11/164 (6%)
Query: 225 LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
+G T+ + +GN R SL G + + + LD E N + + VLQ + Q
Sbjct: 1173 MGSMGTVWAQYGNGNARVCGSLVPPAGQITVAQAAMLDYEQNPR-HKLVLQAETQQ---- 1227
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
+ A + I LLDLNDN P F++ Y E P+G ++QV+A D DQG NG+ TY
Sbjct: 1228 -HLSFATLTISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTYS 1286
Query: 345 LDDP---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D K F IDP++G +T +LDRE S + V A +
Sbjct: 1287 FDQSQAMKDLFRIDPQTGAIT--TAAILDREIWSQAHLVVIATD 1328
Score = 79.0 bits (186), Expect = 9e-13
Identities = 79/313 (25%), Positives = 128/313 (40%), Gaps = 24/313 (7%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIP 131
A Q ++ ++T+ + D+NDN P F Y E P G L L
Sbjct: 1223 AETQQHLSFATLTISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQ 1282
Query: 132 LTVPRGLT-IFKDIRAFDRDKPNTPNSDV--------HYSIVSGNDDGHFALESSHKPVL 182
+T + KD+ D + + + +V D G L SS +
Sbjct: 1283 VTYSFDQSQAMKDLFRIDPQTGAITTAAILDREIWSQAHLVVIATDRGSPPLTSSATLTV 1342
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL-ISGNDR 241
L+ V D ++ QL + ++ E + D+ G L Y L + G
Sbjct: 1343 LVTDVND-NSPTTPLQLELSVP----EDAVIGSEILQVTGNDVDSGPALSYTLLVDGAME 1397
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F++ G ++L ++LD + ++ L VQ S + A + + L D+ND
Sbjct: 1398 GAFTMLRYGGQIWLSRQLDYE-----DRKSYSLTVQTSDGKH---LTHAELTLTLQDVND 1449
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP-KGAFSIDPRSGW 360
N PEF Y +SI+E+ G + V ATD+D G+NG +Y++ P GAF I P +G
Sbjct: 1450 NSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSPVGGAFHIHPDNGT 1509
Query: 361 LTVRNQTVLDREA 373
L LD ++
Sbjct: 1510 LFANKLVELDPQS 1522
Score = 77.0 bits (181), Expect = 4e-12
Identities = 54/174 (31%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P T + K++A+DLD+G+ GQ+ Y + + + L K FV+N G
Sbjct: 1790 IRENQPANTPLTKIHAIDLDTGVYGQLFYTM-----LDLAVAGSGMLMGKDMFVVNRTSG 1844
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ +S E F + + A+D GN + ++V+V V +++ PVF ++NF V E
Sbjct: 1845 ELRSKQSFDYERIKVFNMVVKAMDAGNFSATVTVQVLVTGEDEYNPVFISPFFNFEVPEG 1904
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDR 1110
LG V ATD D G + + Y F +PS F I+ TG + + + R
Sbjct: 1905 AVKGESLGHVQATDEDEGADGVVLYSFSKPSPY---FGINETTGNIYLKTDSQR 1955
Score = 73.7 bits (173), Expect = 3e-11
Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 6/163 (3%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKT 1048
F I G + V +L ES + L + A G G +VRV V D ND+ P +
Sbjct: 209 FSIEADSGWLYVRGALDRESREAYVLAVLASAGPGTRTATCTVRVRVTDENDNSPRLSEE 268
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+ + E + +G+V ATD D G N ++Y + P ++D F I+P TG LS L
Sbjct: 269 RFFLSATENRPPGETVGRVSATDRDAGPNGRVSYRLPPLESD--FHINPHTGELSTRRVL 326
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
DRE + Y L V+A+D G D NDN+P F
Sbjct: 327 DRELQATYQLLVIAQDGG-APPRSVTGTVHITVLDENDNAPTF 368
Score = 73.3 bits (172), Expect = 5e-11
Identities = 45/119 (37%), Positives = 64/119 (53%), Gaps = 7/119 (5%)
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
SG+ R L SLD +G L L + LD + Q +L+VQ P A+AR+ + +
Sbjct: 2 SGDPRGLLSLDPHSGLLSLVRPLDRE-----QTEKLLLEVQGRS-GAPPAYARARLTLYI 55
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
D+NDN P F F+ + + +P G + + ATD D G NG+ Y+LD P G FSID
Sbjct: 56 TDVNDNPPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYELDSP-GPFSID 113
Score = 73.3 bits (172), Expect = 5e-11
Identities = 95/417 (22%), Positives = 169/417 (40%), Gaps = 33/417 (7%)
Query: 513 INPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPD 572
++P++G +S+ E L +E + P Y+ A +T+ +T N P P
Sbjct: 11 LDPHSGLLSLVRPLDREQTEKLLLEVQGRSGAPPA--YARARLTLYIT-DVNDNPPAFP- 66
Query: 573 FMGAPYE-FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
+P+ + S + IG+ + + + D + + + + PF+++ SG +
Sbjct: 67 ---SPFHTLRLQSPIPIGSVIFRAQATDP--DTGFNGQVYYELDSPGPFSIDG-SGQLRA 120
Query: 632 VDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
LS+ YD +A LS TV ++++ E GA + V+
Sbjct: 121 TGLLSQER---YDVRVLASDGGTPQLSSALELTVLLMELQKEPAC---GASD---YRVEV 171
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
+ ++ G G G + + + D A+ G ++ + LDRE R+
Sbjct: 172 REGSPPLSRLLQVRAQPP-GAGEGQLIYRLRPDADAVGFSIEADSGWLYVRGALDRESRE 230
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN 810
Y + V+A G + V + + DENDN P + EN G +
Sbjct: 231 AYVLAVLASAGPG--TRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPPGETV---G 285
Query: 811 IIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
+ ATD D G N Y L + F ++ +TG + LDRE + Y+L ++A+D
Sbjct: 286 RVSATDRDAGPNGRVSYRL-PPLESDFHINPHTGELS-TRRVLDRELQATYQLLVIAQDG 343
Query: 871 GG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
G S + I + DENDN P F + N+ I + +G I ++ K+
Sbjct: 344 GAPPRSVTGTVHITVLDENDNAPTF--LHPNAGKEISLQVMEGKKSGMFIASLQAKD 398
Score = 68.1 bits (159), Expect = 2e-09
Identities = 54/191 (28%), Positives = 83/191 (43%), Gaps = 13/191 (6%)
Query: 161 YSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL----VIMASGKRIHKEILFPE 216
Y++ G D S PVL+ VLD + F V+++ + E+L
Sbjct: 1641 YNLTLGASDRGVPQRSHSVPVLI--NVLDINDNPPVFPRPLYSVLLSEEAPVGSEVL--- 1695
Query: 217 PIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G + Y + SG++ +LF ++ G++ L + LD + + L
Sbjct: 1696 RVLAQDSDSGSNGLVHYSITSGDESRLFQINEATGAIRLARHLDRERQALHALVVLALDG 1755
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
Q Q N L V IE+ D+NDN P F V SI EN P + ++ A D D G
Sbjct: 1756 QGGQANFAL----VPVTIEVRDINDNKPYFPVQILTTSIRENQPANTPLTKIHAIDLDTG 1811
Query: 337 ENGEFTYQLDD 347
G+ Y + D
Sbjct: 1812 VYGQLFYTMLD 1822
Score = 67.3 bits (157), Expect = 3e-09
Identities = 87/329 (26%), Positives = 137/329 (41%), Gaps = 38/329 (11%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF----------------LIAP 123
+ +T+ ++DVNDN P F + Y V++ E G F +++P
Sbjct: 1437 HAELTLTLQDVNDNSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSP 1496
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
+G + I P T+F + + + D P +P DV +V D G +L S L
Sbjct: 1497 VGGAFHIH---PDNGTLFAN-KLVELD-PQSPLVDV---LVEARDHGSPSLASLTTVQFL 1548
Query: 184 LRKVLDYDAGDKEFQL-VIMASGKRIHKEILFPEPIHA-IDQDLGVGATLRYELISGNDR 241
+ D+ + Q + + +L E A Q+ A L Y ++SGN
Sbjct: 1549 VVDANDHSPTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQE---NAALDYTILSGNTD 1605
Query: 242 KLFSLDSV----NGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQARVEIEL 296
F + S NG + L + +A +F L + AS P ++ V I +
Sbjct: 1606 NAFQVQSGMRFWNGRFQQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINV 1665
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
LD+NDN P F Y++ + E P G VL+V+A D D G NG Y + D F I
Sbjct: 1666 LDINDNPPVFPRPLYSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITSGDESRLFQI 1725
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ +G +R LDRE + + V A
Sbjct: 1726 NEATG--AIRLARHLDRERQALHALVVLA 1752
Score = 66.9 bits (156), Expect = 4e-09
Identities = 87/365 (23%), Positives = 143/365 (39%), Gaps = 27/365 (7%)
Query: 511 FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA-VVTIEVTRGTKGNKPD 569
F ++ TG++ + E + S + + Y VV IEV +
Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVE--VQDRNDH 576
Query: 570 IPDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGYEEGVP---FAVE 623
P F P V + +G+SV + +D + V Y LL + G P F ++
Sbjct: 577 SPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLR-QDPGSPGSTFRLD 635
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENANLS----IVTNATVHVVDVNDERGVLLKG 679
+GV+ V L R Y A + N+S A V + D ND +
Sbjct: 636 AETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFI-- 693
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+P++ + E+ + I+ G+ G V + + D G +
Sbjct: 694 --TPLVVWLPEDLPVGSTA-IYMVAQDPDLGDN-GKVGYQLVGGNDEGKFQLHPSSGALT 749
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+ LDRE + Y +TV+A + G + +++ + D ND P FE Y+ + EN
Sbjct: 750 VVRTLDRETTEGYNLTVVA-MDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQEN 808
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+GT + + A D D G + Y G + F +D TGV+ LDRE K
Sbjct: 809 QPVGTTVLR---VVALDRDLGQSGRVTYG--GVSGDEFALDPETGVLT-TKVPLDREAKE 862
Query: 860 MYKLS 864
+YKL+
Sbjct: 863 LYKLT 867
Score = 66.1 bits (154), Expect = 7e-09
Identities = 108/456 (23%), Positives = 196/456 (42%), Gaps = 55/456 (12%)
Query: 425 VGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKA 484
V E ++ L S V+ ++DAND++P F S Y S+ + +G+ + ++
Sbjct: 1525 VDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQ-YSASVPEDLPLGSTVLILEV 1583
Query: 485 VDPDLGQNGMVL-YDLQ--RTSN-LTITSPFKI----NPNTGTVSVAESPILEGR--HAL 534
D D Q L Y + T N + S + G++ + +S E + L
Sbjct: 1584 TDADFTQENAALDYTILSGNTDNAFQVQSGMRFWNGRFQQIGSIILTDSLDFEAISFYNL 1643
Query: 535 FVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQ 594
+ ASD+ +R +S+ V+ I V N P P + Y + +G+ V +
Sbjct: 1644 TLGASDRGV--PQRSHSVPVL-INVL-DINDNPPVFPRPL---YSVLLSEEAPVGSEVLR 1696
Query: 595 IRVNDAFEQND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
+ D+ ++ V Y + G E + F + E +G I + L R + ++ +AL
Sbjct: 1697 VLAQDSDSGSNGLVHYSITSGDESRL-FQINEATGAIRLARHLDRERQALHALVVLALDG 1755
Query: 653 N---ANLSIVTNATVHVVDVNDERG-----VLLKG------AHSPII-FHVKENSAGAAI 697
AN ++V T+ V D+ND + +L A++P+ H + G
Sbjct: 1756 QGGQANFALVP-VTIEVRDINDNKPYFPVQILTTSIRENQPANTPLTKIHAIDLDTGV-Y 1813
Query: 698 GQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV 756
GQ+F+T + ++ G+G L+ V + + G + +++ D E+ V+ M V
Sbjct: 1814 GQLFYTMLDLAVAGSG-----MLMGKDMFVVNRTS----GELRSKQSFDYERIKVFNMVV 1864
Query: 757 IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATD 816
A + G S QV + EDE + PVF + + E + G + ++ATD
Sbjct: 1865 KA-MDAGNFSATVTVQVLVTGEDEYN--PVFISPFFNFEVPEGAVKGESL---GHVQATD 1918
Query: 817 ADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
DEG + + +Y+ F + F ++E TG + DS
Sbjct: 1919 EDEGADGVVLYS-FSKPSPYFGINETTGNIYLKTDS 1953
Score = 64.9 bits (151), Expect = 2e-08
Identities = 49/168 (29%), Positives = 86/168 (51%), Gaps = 16/168 (9%)
Query: 226 GVGATLRYELIS---GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ-- 280
G + +RY L+ G+ F LD+ G L++ + LD + + ++++L V+AS
Sbjct: 611 GPNSQVRYSLLRQDPGSPGSTFRLDAETGVLYVAQALDRE-----EVSSYLLVVEASDQA 665
Query: 281 LN-NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+N + ++ + + D ND+ P+F + + E+LP G + + ++A D D G+NG
Sbjct: 666 VNVSQQRSTSVTARVFISDRNDHAPQFITPLV-VWLPEDLPVGSTAIYMVAQDPDLGDNG 724
Query: 340 EFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ YQL + +G F + P SG LTV LDRE + V A +
Sbjct: 725 KVGYQLVGGNDEGKFQLHPSSGALTV--VRTLDRETTEGYNLTVVAMD 770
Score = 63.7 bits (148), Expect = 4e-08
Identities = 91/366 (24%), Positives = 146/366 (39%), Gaps = 44/366 (12%)
Query: 992 FVINERHGHVIVARSLPPESE----FRLNISALDGGNLN----DNISVRVFVKDVNDHFP 1043
F+++ + G + + L ES+ FR+++ + +L + + V V+D NDH P
Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHSP 578
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADF-GQNANLTYFIQPSDTDLP---FEISPLT 1099
F + V E + + A+D D G N+ + Y + D P F + T
Sbjct: 579 AFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLDAET 638
Query: 1100 GVLSVNGELDRETEDKYILTVVARDN--GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
GVL V LDRE Y+L V A D D ND++P+F L
Sbjct: 639 GVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQF--ITPL 696
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI----GNGNGL 1213
+ W PE + + V P + +N +G + V ND +G
Sbjct: 697 VVWL-PEDLPVGSTAIYMVAQDP----DLGDNGKVGYQL--VGGNDEGKFQLHPSSGALT 749
Query: 1214 ILYSLPQRKNQ-QNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
++ +L + + NL G P LSST L V++ DV DE +KP Y+ +
Sbjct: 750 VVRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKP-----QYDAQ 804
Query: 1266 IEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV 1325
++E N PV L + + + + F +DP G L DRE
Sbjct: 805 VQE--NQPVGTTVLRVVALDRDLGQSGRVTYGGVSG--DEFALDPETGVLTTKVPLDREA 860
Query: 1326 KDTYEV 1331
K+ Y++
Sbjct: 861 KELYKL 866
Score = 63.3 bits (147), Expect = 5e-08
Identities = 81/295 (27%), Positives = 118/295 (40%), Gaps = 59/295 (20%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ GT + + A D DSG NG++ Y S V F I+ +G
Sbjct: 1463 ILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSPV--------------GGAFHIHPDNG 1508
Query: 1000 HVIVAR--SLPPESEF-RLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + L P+S + + A D G+ L +V+ V D NDH P F ++ Y+ +V
Sbjct: 1509 TLFANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQYSASV 1568
Query: 1055 EEAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISP----------LTGVLS 1103
E + ++ TDADF Q NA L Y I +TD F++ G +
Sbjct: 1569 PEDLPLGSTVLILEVTDADFTQENAALDYTILSGNTDNAFQVQSGMRFWNGRFQQIGSII 1628
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
+ LD E Y LT+ A D G D+NDN P
Sbjct: 1629 LTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVL-DINDNPP-------------- 1673
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL 1218
V P+Y + E AP+G+ V +V A D+D NGL+ YS+
Sbjct: 1674 ------------VFPRPLYSVLLSEEAPVGSEVLRVLAQDSD--SGSNGLVHYSI 1714
Score = 62.5 bits (145), Expect = 9e-08
Identities = 78/278 (28%), Positives = 108/278 (38%), Gaps = 52/278 (18%)
Query: 944 IPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIV 1003
IPIG+ I + A D D+G NGQ+ YE +S P S D R
Sbjct: 78 IPIGSVIFRAQATDPDTGFNGQVYYELDS-----PGPFSIDGSGQLR------------- 119
Query: 1004 ARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
A L + + + + A DGG L+ + + V + ++ P + Y V E
Sbjct: 120 ATGLLSQERYDVRVLASDGGTPQLSSALELTVLLMELQKE-PACGASDYRVEVREGSPPL 178
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
L +V A G+ L Y ++P + F I +G L V G LDRE+ + Y+L V+
Sbjct: 179 SRLLQVRAQPPGAGEG-QLIYRLRPDADAVGFSIEADSGWLYVRGALDRESREAYVLAVL 237
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPV 1181
A + D NDNSP+ LS F
Sbjct: 238 A--SAGPGTRTATCTVRVRVTDENDNSPR-----------------LSEERF-------F 271
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP 1219
AT EN P G TV +V A D D NG + Y LP
Sbjct: 272 LSAT--ENRPPGETVGRVSATDRD--AGPNGRVSYRLP 305
Score = 62.1 bits (144), Expect = 1e-07
Identities = 77/330 (23%), Positives = 139/330 (42%), Gaps = 30/330 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGPSLTI 130
G+ Q S + V + + D+NDN P+F Y V + E P G + L + G + +
Sbjct: 1651 GVPQRSHSVPVLINVLDINDNPPVFPRPLYSVLLSEEAPVGSEVLRVLAQDSDSGSNGLV 1710
Query: 131 PLTVPRG--LTIFKDIRAFDRDKP----NTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
++ G +F+ A + + +H +V D + PV +
Sbjct: 1711 HYSITSGDESRLFQINEATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTI- 1769
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFP-EPIHAIDQDLGVGATLRYEL----ISGN 239
+V D + F + I+ + R ++ P IHAID D GV L Y + ++G+
Sbjct: 1770 -EVRDINDNKPYFPVQILTTSIRENQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGS 1828
Query: 240 D----RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
+ +F ++ +G L ++ D + + F + V+A N +A V++
Sbjct: 1829 GMLMGKDMFVVNRTSGELRSKQSFDYE-----RIKVFNMVVKAMDAGN--FSATVTVQVL 1881
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
+ ++ P F F+N + E G S+ V ATD+D+G +G Y P F I+
Sbjct: 1882 VTGEDEYNPVFISPFFNFEVPEGAVKGESLGHVQATDEDEGADGVVLYSFSKPSPYFGIN 1941
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G + ++ D + H S R K +E
Sbjct: 1942 ETTGNIYLKT----DSQRHRSGRSKRETRE 1967
Score = 59.7 bits (138), Expect = 6e-07
Identities = 48/154 (31%), Positives = 70/154 (45%), Gaps = 20/154 (12%)
Query: 936 PLF--LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
PL+ L+ E P+G+ ++++ A D DSG NG + Y S + R F
Sbjct: 1678 PLYSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITSG-------------DESRLFQ 1724
Query: 994 INERHGHVIVARSLPPESE--FRLNISALDGGNLNDN---ISVRVFVKDVNDHFPVFKKT 1048
INE G + +AR L E + L + ALDG N + V + V+D+ND+ P F
Sbjct: 1725 INEATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYFPVQ 1784
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
++ E Q L K+ A D D G L Y
Sbjct: 1785 ILTTSIRENQPANTPLTKIHAIDLDTGVYGQLFY 1818
Score = 59.3 bits (137), Expect = 8e-07
Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 9/149 (6%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+F +D GS+FL ELD +++ V +V+ + L + +E+E+ D ND+
Sbjct: 518 IFMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGY-VPPHVVHIEVEVQDRNDH 576
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQL-----DDPKGAFSIDP 356
P F D + + E+ G SV A+D D G N + Y L P F +D
Sbjct: 577 SPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLDA 636
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G L V LDRE SS + V A +
Sbjct: 637 ETGVLYVAQ--ALDREEVSSYLLVVEASD 663
Score = 54.0 bits (124), Expect = 3e-05
Identities = 58/232 (25%), Positives = 103/232 (44%), Gaps = 21/232 (9%)
Query: 415 EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK 474
E ++Y+ + + N+ +Q + V V + D ND+ P F+ + + +
Sbjct: 651 EVSSYLLVVEASDQAVNVS---QQRSTSVTARVFISDRNDHAPQFITPLVVW--LPEDLP 705
Query: 475 VGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVA---ESPILEGR 531
VG+ + A DPDLG NG V Y L ++ F+++P++G ++V + EG
Sbjct: 706 VGSTAIYMVAQDPDLGDNGKVGYQLVGGND---EGKFQLHPSSGALTVVRTLDRETTEG- 761
Query: 532 HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTS 591
+ L V A D + +L+V ++V + P F Y+ V N +GT+
Sbjct: 762 YNLTVVAMDHGSPRLSSTQTLSVSLLDV-------NDEAPSFEKPQYDAQVQENQPVGTT 814
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMY 643
V +RV S + +G G FA++ +GV+T L R + +Y
Sbjct: 815 V--LRVVALDRDLGQSGRVTYGGVSGDEFALDPETGVLTTKVPLDREAKELY 864
Score = 50.8 bits (116), Expect = 3e-04
Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN+P + S N G +G+V A D D G NG V Y L
Sbjct: 251 VRVRVTDENDNSPRLSEERFF-LSATENRPPGETVGRVSATDRDAGPNGRVSYRLP---- 305
Query: 505 LTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANP 545
+ S F INP+TG +S L+ + L V A D A P
Sbjct: 306 -PLESDFHINPHTGELSTRRVLDRELQATYQLLVIAQDGGAPP 347
Score = 50.0 bits (114), Expect = 5e-04
Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y L F ++ G L + LD + LQA T+ L V
Sbjct: 287 VSATDRDAGPNGRVSYRLPPLESD--FHINPHTGELSTRRVLDRE----LQA-TYQLLVI 339
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEF----EVDFYNISIVENLPNGFSVLQVMATDK 333
A P ++ V I +LD NDN P F ++ ++E +G + + A D
Sbjct: 340 AQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDP 399
Query: 334 DQGENGEFTYQL 345
D+GENG TY L
Sbjct: 400 DEGENGTVTYSL 411
Score = 49.2 bits (112), Expect = 9e-04
Identities = 41/135 (30%), Positives = 61/135 (45%), Gaps = 14/135 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V+V + ++ NPVF+ S + F + A G +G V+A D D G +G+VLY +
Sbjct: 1876 VTVQVLVTGEDEYNPVFI-SPFFNFEVPEGAVKGESLGHVQATDEDEGADGVVLYSFSKP 1934
Query: 503 SNLTITSPFKINPNTGTV--SVAESPILEGR-----HALFVEASDQPANPSERRYSLAVV 555
S F IN TG + GR + +E PS R + A V
Sbjct: 1935 SPY-----FGINETTGNIYLKTDSQRHRSGRSKRETREMTLEVHAHSPLPSS-RVATAQV 1988
Query: 556 TIEVTRGTKGNKPDI 570
T++VT + G PD+
Sbjct: 1989 TVDVTHTSFGLAPDL 2003
Score = 48.0 bits (109), Expect = 0.002
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D G+ + Y K LF +D G++ LD E QA+ V+ A
Sbjct: 1272 AEDPDQGLNGQVTYSFDQSQAMKDLFRIDPQTGAI--TTAAILDREIWSQAHLVVI---A 1326
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+ +P T+ A + + + D+NDN P + +S+ E+ G +LQV D D G
Sbjct: 1327 TDRGSPPLTSSATLTVLVTDVNDNSPTTPLQL-ELSVPEDAVIGSEILQVTGNDVDSGPA 1385
Query: 339 GEFTYQLDDP-KGAFSIDPRSG--WLTVRNQTVLDREAHS 375
+T +D +GAF++ G WL+ R DR+++S
Sbjct: 1386 LSYTLLVDGAMEGAFTMLRYGGQIWLS-RQLDYEDRKSYS 1424
Score = 47.6 bits (108), Expect = 0.003
Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 23/149 (15%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G T+ +++A D D+G NG++ Y +PP L +D F IN G +
Sbjct: 276 ENRPPGETVGRVSATDRDAGPNGRVSYR------LPP--LESD-------FHINPHTGEL 320
Query: 1002 IVARSLPPE--SEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVF----KKTWYNFN 1053
R L E + ++L + A DGG ++ +V + V D ND+ P F +
Sbjct: 321 STRRVLDRELQATYQLLVIAQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQ 380
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTY 1082
V E + + + + A D D G+N +TY
Sbjct: 381 VMEGKKSGMFIASLQAKDPDEGENGTVTY 409
Score = 43.6 bits (98), Expect = 0.043
Identities = 53/229 (23%), Positives = 91/229 (39%), Gaps = 29/229 (12%)
Query: 1248 EVEMSDK----PVFISRYYELEIEENVNAPVELVSLNLTEHY---ENFKMRYYILNENDT 1300
EVE+ D+ P F L + E+ + + + ++H N ++RY +L ++
Sbjct: 567 EVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPG 626
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
TF +D G LY+ ++ DRE +Y ++V A Q + +
Sbjct: 627 SPGSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQAVN--------------VSQQR 672
Query: 1361 KYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG----YQVMQLKGAIGHHPTASR 1416
V V I D ND++P+F PLV +P P G Y V Q +G +
Sbjct: 673 STSVTARVFISDRNDHAPQFIT---PLVVWLPEDLPVGSTAIYMVAQ-DPDLGDNGKVGY 728
Query: 1417 TVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRFA 1465
+ DE F S LT + D + ++ ++ +PR +
Sbjct: 729 QLVGGNDEGKFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLS 777
Score = 40.7 bits (91), Expect = 0.30
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
+++ DVND+ P F ++ ++ V+ + ATD D G N + Y + D+ P
Sbjct: 53 LYITDVNDNPPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYEL---DSPGP 109
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F I +G L G L +E +Y + V+A D G
Sbjct: 110 FSIDG-SGQLRATGLLSQE---RYDVRVLASDGG 139
>UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=5;
Gallus gallus|Rep: GammaA-like protocadherin precursor -
Gallus gallus (Chicken)
Length = 811
Score = 109 bits (262), Expect = 6e-22
Identities = 125/471 (26%), Positives = 193/471 (40%), Gaps = 41/471 (8%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
M +EV + D NDN P F + E A +G +A DPD+G N + Y L
Sbjct: 115 MKVYPIEVEITDINDNTPSFGEGQI-ELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYAL 173
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASD--QPANPSERRYSLAV 554
+ +++ + V + H L + ASD PA R +AV
Sbjct: 174 SGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAV 233
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH 612
+ + P F A Y V +V +G+++ ++ D + DV Y
Sbjct: 234 LDAN---------DNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQE 284
Query: 613 GYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
E+ F +E ++G I +V +L Y+F V + LS TV V DVND
Sbjct: 285 VLEQISNTFHIEPKTGAIRLVRNLDFEEADFYEF-LVQAHDGGGLSDDAKITVSVTDVND 343
Query: 672 ERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
+ ++ A S I E++A + + H NG VR + +
Sbjct: 344 NAPEISVRSALSEI----SEDAAPGTVVALLHVQDRDSGANG--EVRCSLGEGVPFRLER 397
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
A+ + ++ T + LDRE+ Y +TV A +G + + + D NDN PVF A
Sbjct: 398 ALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAV-LALRVLDVNDNAPVFAEA 456
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-------EMFDVDENT 843
Y + EN+ G + ++A DAD G NA Y L EG+ V T
Sbjct: 457 RYSARLPENNAEGALVL---TVRAWDADWGQNARVRYRL-REGRLRGAPLSSYVSVQAET 512
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
G + + S D E+ +L + A D G LSS + ++I DENDN P+
Sbjct: 513 GAL-YALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQ 562
Score = 79.4 bits (187), Expect = 7e-13
Identities = 63/240 (26%), Positives = 112/240 (46%), Gaps = 21/240 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIAN 722
V + D+ND +G ++ N A IG + + GT +++ + ++
Sbjct: 122 VEITDINDNTPSFGEGQ-----IELRTNEM-AVIGMRYALRRAHDPDMGTNSLQSYALSG 175
Query: 723 QQDVTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ + + DG + K LDRE+ + + + A + G + G ++ + +
Sbjct: 176 DEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRAS-DGGDPARTGTARIRVAVL 234
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-- 836
D NDN P F A Y + E+ +G+ + + ATD D+GTN Y LF E E
Sbjct: 235 DANDNAPAFSQAVYTVRVPEDVPVGSTLLR---VTATDPDDGTNGDVKY-LFQEVLEQIS 290
Query: 837 --FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
F ++ TG ++ + + LD E+ Y+ + A D GGLS +A++ + + D NDN PE +
Sbjct: 291 NTFHIEPKTGAIRLVRN-LDFEEADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAPEIS 349
Score = 79.0 bits (186), Expect = 9e-13
Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++P+G+T++++ A D D G NG ++Y F + ++ F I + G
Sbjct: 252 VPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLE-----------QISNTFHIEPKTG 300
Query: 1000 HVIVARSLP-PESEF-RLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + R+L E++F + A DGG L+D+ + V V DVND+ P + E
Sbjct: 301 AIRLVRNLDFEEADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAPEISVRSALSEISED 360
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS-PLTGVLSV--NGELDRETED 1114
V+ + D D G N + + +PF + L SV ELDRE
Sbjct: 361 AAPGTVVALLHVQDRDSGANGEVRCSL---GEGVPFRLERALDDYYSVVTARELDRERAS 417
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +TV A D G DVNDN+P F
Sbjct: 418 EYNVTVRAADGG-SPALRSGAVLALRVLDVNDNAPVF 453
Score = 73.7 bits (173), Expect = 3e-11
Identities = 54/154 (35%), Positives = 80/154 (51%), Gaps = 12/154 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL---QANTFVLQV 276
A D D+G + Y L SG++ FSL SV EK +L L +A L +
Sbjct: 158 AHDPDMGTNSLQSYAL-SGDEH--FSL-SVQAGADGEKRPELVLAKALDREEAAFHELLL 213
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+AS +P +T AR+ + +LD NDN P F Y + + E++P G ++L+V ATD D G
Sbjct: 214 RASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDG 273
Query: 337 ENGEFTY----QLDDPKGAFSIDPRSGWL-TVRN 365
NG+ Y L+ F I+P++G + VRN
Sbjct: 274 TNGDVKYLFQEVLEQISNTFHIEPKTGAIRLVRN 307
Score = 67.7 bits (158), Expect = 2e-09
Identities = 74/258 (28%), Positives = 109/258 (42%), Gaps = 24/258 (9%)
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
V+ H L+ A T+ V N A ++ L I E+ GT + L+ D DSG
Sbjct: 320 VQAHDGGGLSDDAKITV-SVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSG 378
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISA 1019
NG++R V P +L AL+ Y+ V+ AR L E SE+ + + A
Sbjct: 379 ANGEVRCSLGEGV---PFRLER-ALD--DYY-------SVVTARELDRERASEYNVTVRA 425
Query: 1020 LDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
DGG+ L + + V DVND+ PVF + Y+ + E ++ V A DAD+GQN
Sbjct: 426 ADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQN 485
Query: 1078 ANLTYFIQP-----SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
A + Y ++ + + TG L D E + L V A D G
Sbjct: 486 ARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGG-APPLS 544
Query: 1133 XXXXXXXXXXDVNDNSPK 1150
D NDN+P+
Sbjct: 545 SNVSVRLLIADENDNAPQ 562
Score = 66.9 bits (156), Expect = 4e-09
Identities = 52/170 (30%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
E+ +++A++L E L + A DGG+ +RV V D ND+ P F + Y
Sbjct: 190 EKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYT 249
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP--SDTDLPFEISPLTGVLSVNGELD 1109
V E L +V ATD D G N ++ Y Q F I P TG + + LD
Sbjct: 250 VRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQISNTFHIEPKTGAIRLVRNLD 309
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
E D Y V A D G DVNDN+P+ L E
Sbjct: 310 FEEADFYEFLVQAHDGG---GLSDDAKITVSVTDVNDNAPEISVRSALSE 356
Score = 57.2 bits (132), Expect = 3e-06
Identities = 43/150 (28%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+H D+D G +R L G +L S+ +ELD + +A+ + + V+
Sbjct: 370 LHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRE-----RASEYNVTVR 424
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ +P + A + + +LD+NDN P F Y+ + EN G VL V A D D G+
Sbjct: 425 AADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQ 484
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQT 367
N Y+L + G P S +++V+ +T
Sbjct: 485 NARVRYRLRE--GRLRGAPLSSYVSVQAET 512
Score = 56.8 bits (131), Expect = 4e-06
Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 9/169 (5%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G + T + +DRE+ + V +Y + + I D NDN P F
Sbjct: 80 ASSGHLVTAERIDREQLCRLLEKCVLRCELIVEGEMKVYPIEVEITDINDNTPSFGEGQI 139
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK----F 848
E E + IG + +A D D GTN+L Y L G+ V K
Sbjct: 140 ELRTNEMAVIGMRYALR---RAHDPDMGTNSLQSYALSGDEHFSLSVQAGADGEKRPELV 196
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ +LDRE+ ++L L A D G + A + + + D NDN P F+Q
Sbjct: 197 LAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQ 245
Score = 53.6 bits (123), Expect = 4e-05
Identities = 56/200 (28%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 711 NGT-GNVRFLIANQ-QDVTDDIAIA-EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
+GT G+V++L + +++ I + G I + LD E+ D Y V A G+
Sbjct: 272 DGTNGDVKYLFQEVLEQISNTFHIEPKTGAIRLVRNLDFEEADFYEFLVQAHDGGGLSDD 331
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
A ++T+ + D NDN P + I E++ GT + + + D D G N
Sbjct: 332 A---KITVSVTDVNDNAPEISVRSALSEISEDAAPGTVVAL---LHVQDRDSGANGEVRC 385
Query: 828 TLFGEGKEMF---DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIM 882
+L GEG +D+ VV LDRE+ Y +++ A D G L S A L +
Sbjct: 386 SL-GEGVPFRLERALDDYYSVVT--ARELDRERASEYNVTVRAADGGSPALRSGAVLALR 442
Query: 883 IGDENDNKPEFNQIEENSKV 902
+ D NDN P F + ++++
Sbjct: 443 VLDVNDNAPVFAEARYSARL 462
Score = 48.0 bits (109), Expect = 0.002
Identities = 43/155 (27%), Positives = 65/155 (41%), Gaps = 25/155 (16%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G P+ + TA + V V D D P F Y + + E+V L+ + T+ +
Sbjct: 219 GDPARTGTARIRVAVLDANDNA-----PAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDG 273
Query: 1288 FKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
Y+ E I TF I+P+ G + LVR+ D E D YE +V+A
Sbjct: 274 TNGDVKYLFQEVLEQISNTFHIEPKTGAIRLVRNLDFEEADFYEFLVQAHD--------- 324
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
G D K+ V + DVNDN+P+ +
Sbjct: 325 ----------GGGLSDDAKITVSVTDVNDNAPEIS 349
Score = 45.2 bits (102), Expect = 0.014
Identities = 45/155 (29%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + +LD NDN PVF + Y + N G ++ V+A D D GQN V Y
Sbjct: 433 LRSGAVLALRVLDVNDNAPVFAEAR-YSARLPENNAEGALVLTVRAWDADWGQNARVRYR 491
Query: 499 LQ--RTSNLTITSPFKINPNTGTVSVAES-PILEGRHA-LFVEASDQPANPSERRYSLAV 554
L+ R ++S + TG + S E R L+V A D A P S+ +
Sbjct: 492 LREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRL 551
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIG 589
+ + N P + AP GS G+G
Sbjct: 552 LIAD----ENDNAPQVLYPPAAPGP-GPGSGAGVG 581
Score = 43.2 bits (97), Expect = 0.056
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 9/170 (5%)
Query: 218 IHAIDQDLGVGATLRY--ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G ++Y + + F ++ G++ L + LD + +A+ +
Sbjct: 265 VTATDPDDGTNGDVKYLFQEVLEQISNTFHIEPKTGAIRLVRNLDFE-----EADFYEFL 319
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA + A++ + + D+NDN PE V I E+ G V + D+D
Sbjct: 320 VQAHDGGG--LSDDAKITVSVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDS 377
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NGE L + + +V LDRE S + V A +
Sbjct: 378 GANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAAD 427
>UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles
gambiae|Rep: ENSANGP00000018135 - Anopheles gambiae str.
PEST
Length = 1880
Score = 109 bits (262), Expect = 6e-22
Identities = 164/682 (24%), Positives = 280/682 (41%), Gaps = 77/682 (11%)
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK 483
K+ E++ M+ +++T+LD NDNNP F Y+ S+ N++ G + V
Sbjct: 920 KLACVVEDVAAERGDQMANTFLKITVLDENDNNPKF-RKPFYKHSIAENSQYGVAVCTVV 978
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQ 541
A D D QN V Y L+ + ++ TG + V E L V A+D
Sbjct: 979 AEDAD--QNKTVKYSLEGEKG--VLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAADT 1034
Query: 542 PANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF 601
P R S V ++V N P F+ + +++V N +G + I D
Sbjct: 1035 GTPP---RASFVEVFVQVLDENDNN----PYFVDSVNDYYVSENASVGAEIAIILAKD-L 1086
Query: 602 EQND---VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE------ 652
+ D ++Y +L F+++ G++ V L R Y A
Sbjct: 1087 DSGDFGRITY-ILDRVSSKEKFSIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYL 1145
Query: 653 -NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN 711
+ + + +HV+D ND V+ K + +I + ++ I ++ T+ N
Sbjct: 1146 NGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMI--TEYHNINDPIVKLRATDADDPT-N 1202
Query: 712 GTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
G G + F I + + + A+ I+++ PL + Y + +I + G +
Sbjct: 1203 GNGQLSFDIVDPSGIFYIQQVSAQYAEIYSRGPL-KNLHGNYTLELIVS-DLGGVPNTAR 1260
Query: 771 YQVTIYIEDENDNPPVF--EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
V I + D ND+ PVF + EN+ +G + A D D G NA+ Y
Sbjct: 1261 ETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQ---VHAYDEDVGENAIVRYR 1317
Query: 829 L----FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELII 881
L G ++ F +D+ TG + + SLDRE+++MY L + A D G LSS +LI+
Sbjct: 1318 LKMDTMGNFRK-FSLDKETGELS-LAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDLIV 1375
Query: 882 MIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
+ D NDN P+F + +E LN T T + + +D D L PL P
Sbjct: 1376 YVRDVNDNLPQF----------LLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLD-GP 1424
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
+ I+ N D GL+ + ++ E + K S L +K
Sbjct: 1425 AASVVCYYIVHGNE-DGHFGLD-PVSHDLTVEKELDREKKSLYKLHIK------------ 1470
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
A + L+ ++ GNL + V++ D+ND+ PVF+ + + +
Sbjct: 1471 --ATEECTNANLSLDTTS-HSGNL---LKATVYINDINDNSPVFESKIFTGGISTSSLFG 1524
Query: 1062 RVLGKVDATDADFGQNANLTYF 1083
+ ++ ATD D G N + Y+
Sbjct: 1525 ATILQLQATDEDDGLNGLVRYY 1546
Score = 95.5 bits (227), Expect = 1e-17
Identities = 188/743 (25%), Positives = 285/743 (38%), Gaps = 105/743 (14%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG-QNGMVLY 497
L + V V V + D ND PVF+ S Y + + G + +V A+D D N V Y
Sbjct: 720 LTAQVEVTVYVQDVNDYAPVFLESQ-YAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTY 778
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+Q+ + F I +TG +S+ L+ + A D A S Y L V
Sbjct: 779 RIQQGGD----GRFVIGASTGEISITHGASLDPN----LLAPD--ALGSGSTYVLEVFA- 827
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL------- 610
T G G++ G+ + +N +GT V ++ D E + Y +
Sbjct: 828 --TDGGNGDQ----QLQGS----CLVNNTPVGTEVYRLMATDPDEGAMLRYYIDRSLSEG 877
Query: 611 ---------LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA---LQENANLSI 658
L Y+ F + E +G++ + L R V E +
Sbjct: 878 KTEEGALVKLDDYDFAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMA 937
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFH-VKENSA-GAAIGQIFHTNMSSIYGNGTGNV 716
T + V+D ND K P H + ENS G A+ + + N T V
Sbjct: 938 NTFLKITVLDENDNNPKFRK----PFYKHSIAENSQYGVAVCTVVAEDADQ---NKT--V 988
Query: 717 RFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
++ + ++ V + + + ++ G I + +D E+ +V A + G A +V +
Sbjct: 989 KYSLEGEKGVLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAA-DTGTPPRASFVEVFV 1047
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ DENDN P F + + ++ EN+ +G EI II A D D G Y L
Sbjct: 1048 QVLDENDNNPYFVDSVNDYYVSENASVGAEIA---IILAKDLDSGDFGRITYIL------ 1098
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDEN-DNKPEFN 894
D + KF S+D EK I+ R G L E M+ E DN P +
Sbjct: 1099 ----DRVSSKEKF---SIDPEKGIL-------RVAGALDREETAEYMLAVEAWDNYP-YG 1143
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
+ S+ +I V N + + +I E I I+KL
Sbjct: 1144 YLNGESRNAFKH----------ILIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLR 1193
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
A D D NG + F+ + PS + +Y I R G + ++L
Sbjct: 1194 ATDADDPTNGNGQLSFD---IVDPSGIFYIQQVSAQYAEIYSR-GPL---KNLHGNYTLE 1246
Query: 1015 LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK----VDAT 1070
L +S L G +V + V D NDH PVF N V+ + T LGK V A
Sbjct: 1247 LIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENT--TLGKPFFQVHAY 1304
Query: 1071 DADFGQNANLTYFIQPSDTD--LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D D G+NA + Y ++ F + TG LS+ LDRE + Y L + A D G
Sbjct: 1305 DEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIP 1364
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P+F
Sbjct: 1365 TPLSSTVDLIVYVRDVNDNLPQF 1387
Score = 78.6 bits (185), Expect = 1e-12
Identities = 120/499 (24%), Positives = 199/499 (39%), Gaps = 50/499 (10%)
Query: 441 SFVNVEVTLL--DANDNNPVFVP-SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+FV LL D NDN P+F P +++ E + S + T + +AVD D G G V+Y
Sbjct: 150 NFVTQSFLLLVEDINDNEPIFKPFASVLEVAEDSPPGILTTL---EAVDKDEGAYGQVVY 206
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+Q S + G V +A + E +H + + R + +
Sbjct: 207 YIQGLSEENNVFSISTSNGKGVVRLARALDYERQHFYHINVLAVD-RAIQGRINTGTAAL 265
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI-----RVNDAFEQNDVSYDLLH 612
V ++P P+F+ + + IGT V + V ++ +++
Sbjct: 266 LVRVKDVEDQP--PEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNRIIY 323
Query: 613 GYEEGVP--FAVEERSGVITVVDDLSRYN--RPM---YDFEAVALQENANL---SIVTNA 662
G F ++ G + L R + P+ + E VA++E+ S
Sbjct: 324 GISNNGSELFEIDRLKGSLRTKQKLDREDSTNPINGAFILEVVAIEESKLQPAPSSTMEI 383
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSI--YGNG-TGNVRFL 719
TV V DVNDE + + EN+ + + +++ + Y G G R
Sbjct: 384 TVIVTDVNDEIPRFRSDGYE---CEIGENAQENTLARFIDGSINEVFDYDQGKNGTFRLS 440
Query: 720 IANQQDVTDDI---AIAEDGTIFTQKP---LDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ D+ + I AI E K LD E+ +TV+A + Q+
Sbjct: 441 LHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVVASEVESA-GRTSTAQI 499
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE---GTNALFMYTLF 830
+ + D+NDN P F YE + EN GT + ++ATD+D GT + L
Sbjct: 500 RVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQ---LQATDSDSGLFGTEGVRYANLT 556
Query: 831 GEGKEMFDVDENTGVVKFIGDS---LDREKKIMYKLSLVARDTGGLSSE--AELIIMIGD 885
G +D + G V + DRE + LS+ ARD GG + LI+ + D
Sbjct: 557 GSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTVPLILNVLD 616
Query: 886 ENDNKPEFNQIEENSKVRI 904
NDN P F +++ +VR+
Sbjct: 617 VNDNAPVF--VQKRYEVRL 633
Score = 74.1 bits (174), Expect = 3e-11
Identities = 117/501 (23%), Positives = 204/501 (40%), Gaps = 51/501 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPD--LGQNG 493
E +F ++ + +LD NDN PV PS + N + I K++A D D NG
Sbjct: 1148 ESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHN--INDPIVKLRATDADDPTNGNG 1205
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYS 551
+ +D+ S + +++ + + P+ L G + L + SD P+ R
Sbjct: 1206 QLSFDIVDPSGIFYIQ--QVSAQYAEI-YSRGPLKNLHGNYTLELIVSDLGGVPNTARE- 1261
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYD 609
T+++ + + V N +G Q+ D E V Y
Sbjct: 1262 ----TVDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVRYR 1317
Query: 610 L-LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHV 666
L + F++++ +G +++ L R + MYD A + LS + V+V
Sbjct: 1318 LKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDLIVYV 1377
Query: 667 VDVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTN-MSSIYGNGTGNVRFLIA--N 722
DVND LLK H+ + + + + + G V + I N
Sbjct: 1378 RDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGN 1437
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-------EFNKGVISGAG-IYQVT 774
+ ++ D T+ +K LDREK+ +Y++ + A + S +G + + T
Sbjct: 1438 EDGHFGLDPVSHDLTV--EKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNLLKAT 1495
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+YI D NDN PVFE + G I +S G I ++ATD D+G N L Y GE +
Sbjct: 1496 VYINDINDNSPVFESKIFTGGISTSSLFGATILQ---LQATDEDDGLNGLVRYYRHGEVR 1552
Query: 835 ------------EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIM 882
+ F V+ +TG V + + + + S++A D+ G A + I
Sbjct: 1553 KTLAEGLDDLRSDPFLVEADTGQV-LLNFFPQKSMRGYFDFSVLANDSYGCHDRAHVFIY 1611
Query: 883 IGDENDNKPEFNQIEENSKVR 903
+ E D + +F + S++R
Sbjct: 1612 LIRE-DQRVKFILRQRPSEIR 1631
Score = 73.7 bits (173), Expect = 3e-11
Identities = 84/340 (24%), Positives = 144/340 (42%), Gaps = 43/340 (12%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-----------EKAF---IFLIAPIGPS 127
S + +ED+NDN PIF + V E +P G E A+ ++ I +
Sbjct: 155 SFLLLVEDINDNEPIFKPFASVLEVAEDSPPGILTTLEAVDKDEGAYGQVVYYIQGLSEE 214
Query: 128 LTI-PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRK 186
+ ++ G + + RA D ++ + H ++++ + + + LL +
Sbjct: 215 NNVFSISTSNGKGVVRLARALDYERQHF----YHINVLAVDRAIQGRINTG--TAALLVR 268
Query: 187 VLDYDAGDKEF---QLVIMAS-----GKRIHKEILFPEPIHAIDQDLGVGATLRYELISG 238
V D + EF Q V+ S G + I + A+D D G+ + Y IS
Sbjct: 269 VKDVEDQPPEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNRIIYG-ISN 327
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN--NPLKTAQARVEIEL 296
N +LF +D + GSL +++LD + N F+L+V A + + P ++ + + +
Sbjct: 328 NGSELFEIDRLKGSLRTKQKLDREDSTNPINGAFILEVVAIEESKLQPAPSSTMEITVIV 387
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT-----DKDQGENGEFTYQLDDPKGA 351
D+ND +P F D Y I EN + + D DQG+NG F L P
Sbjct: 388 TDVNDEIPRFRSDGYECEIGENAQENTLARFIDGSINEVFDYDQGKNGTFRLSLHPPSDI 447
Query: 352 FSIDPRSG------WLTVRNQTVLDREAHSSLRMKVYAKE 385
F + P+ L V++ ++LD E L + V A E
Sbjct: 448 FEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVVASE 487
Score = 70.5 bits (165), Expect = 3e-10
Identities = 58/182 (31%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 221 IDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
ID+ L G T L+ +D F L+ NG L + K LD + ++ V V
Sbjct: 870 IDRSLSEGKTEEGALVKLDDYDFAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVA 929
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + + + A ++I +LD NDN P+F FY SI EN G +V V+A D DQ
Sbjct: 930 AERGD---QMANTFLKITVLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDADQ-- 984
Query: 338 NGEFTYQLDDPKGAFS---IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
N Y L+ KG +D +G + VRN+ +D E +S L V A +T +F
Sbjct: 985 NKTVKYSLEGEKGVLELLHVDDETGEIVVRNR--IDHEEYSWLNFSVRAADTGTPPRASF 1042
Query: 395 AD 396
+
Sbjct: 1043 VE 1044
Score = 68.9 bits (161), Expect = 1e-09
Identities = 124/499 (24%), Positives = 205/499 (41%), Gaps = 80/499 (16%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + V +LD NDN P F +YE + N GTV+ +++A D D G G +
Sbjct: 495 STAQIRVVVLDQNDNFPEF-SQPVYEIDVPENVTAGTVLLQLQATDSDSGLFGT---EGV 550
Query: 501 RTSNLT--ITSPFKINPNTGTVSV--AESPILEG----RHALFVEASDQPANPSERRYSL 552
R +NLT I+S ++P+ GTV++ +ESP+ + +H L VEA D + L
Sbjct: 551 RYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTVPL 610
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSY 608
+ ++V + P F+ YE + N S + D+ + V Y
Sbjct: 611 ILNVLDVN-------DNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEY 663
Query: 609 DLLHGYEEGVPFAVEERSGVITVVD--DLSRYNRP--MYDFEAVALQENAN------LSI 658
L+ + F V+ R+G ++V + D R D +AL A L+
Sbjct: 664 RLIGAHHSDY-FHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAADGGEPPLTA 722
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
TV+V DVND V L+ ++ +I ++ +G + ++ + + N +V +
Sbjct: 723 QVEVTVYVQDVNDYAPVFLESQYAIVI--PEDTPSGLPVLRVTAMDGDGSFPN--NHVTY 778
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
I D I A G I + ++A + Y + ++
Sbjct: 779 RIQQGGDGRFVIG-ASTGEISITHGASLDP------NLLA---PDALGSGSTYVLEVFAT 828
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGK- 834
D + + + ++ N+ +GTE+ + ATD DEG A+ Y + EGK
Sbjct: 829 DGGNGDQQLQGSC----LVNNTPVGTEVYR---LMATDPDEG--AMLRYYIDRSLSEGKT 879
Query: 835 --------------EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT----GGLSSE 876
F ++E G++K I LDREK KL+ V D G +
Sbjct: 880 EEGALVKLDDYDFAAAFILNETNGLLK-IAKLLDREKIAEIKLACVVEDVAAERGDQMAN 938
Query: 877 AELIIMIGDENDNKPEFNQ 895
L I + DENDN P+F +
Sbjct: 939 TFLKITVLDENDNNPKFRK 957
Score = 66.1 bits (154), Expect = 7e-09
Identities = 124/503 (24%), Positives = 199/503 (39%), Gaps = 72/503 (14%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ + EN +G I + A DLDSG G+I Y D + K F I+
Sbjct: 1066 YYVSENASVGAEIAIILAKDLDSGDFGRITYIL-------------DRVSSKEKFSIDPE 1112
Query: 998 HGHVIVARSLPPE--SEFRLNISALDG---GNLNDNIS-----VRVFVKDVNDHFPVFKK 1047
G + VA +L E +E+ L + A D G LN + + V D ND+ PV +K
Sbjct: 1113 KGILRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQK 1172
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNAN--LTY-FIQPSDTDLPFEISPLTGVLSV 1104
+ E + K+ ATDAD N N L++ + PS ++S +
Sbjct: 1173 PSGCSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVDPSGIFYIQQVSAQYAEIYS 1232
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
G L + Y L ++ D G D ND++P F K E
Sbjct: 1233 RGPL-KNLHGNYTLELIVSDLGGVPNTARETVDICVT-DFNDHAPVFVVPSGNTTVKVFE 1290
Query: 1165 ADELSNHNFESVMMIPVYKATIEENAPIGTTVAK-VFANDTDF-IGNGNGLILYSLPQRK 1222
L F+ + Y + ENA + + N F + G + + +
Sbjct: 1291 NTTLGKPFFQ----VHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDR 1346
Query: 1223 NQQNL----------GLPS-LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN 1271
QQ + G+P+ LSST L+V V DV D + P F+ + L E++
Sbjct: 1347 EQQMMYDLRIEAYDQGIPTPLSSTVDLIVYVRDVNDNL-----PQFLLKEISLNFTEHMT 1401
Query: 1272 APVELVSLNLTEHYENFK---------MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
E + L T + + YYI++ N+ F +DP + L + + D
Sbjct: 1402 PGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGNEDG---HFGLDPVSHDLTVEKELD 1458
Query: 1323 REVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
RE K Y++ ++A + + L + ++L K V I D+NDNSP F
Sbjct: 1459 REKKSLYKLHIKATEECTNANLSLDTTSHSGNLL--------KATVYINDINDNSPVFE- 1509
Query: 1383 GNRPLVTAIPTTAPFGYQVMQLK 1405
++ I T++ FG ++QL+
Sbjct: 1510 -SKIFTGGISTSSLFGATILQLQ 1531
Score = 66.1 bits (154), Expect = 7e-09
Identities = 69/252 (27%), Positives = 108/252 (42%), Gaps = 42/252 (16%)
Query: 930 DVDQLGPLFLIP---------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
D + P+F++P EN +G +++A D D G N +RY +
Sbjct: 1269 DFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVRY-----------R 1317
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFV 1035
L D + R F +++ G + +A SL E + + L I A D G L+ + + V+V
Sbjct: 1318 LKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDLIVYV 1377
Query: 1036 KDVNDHFPVF--KKTWYNFNVEEAQYTRRVLGKVDATDADF-----GQNANLT-YFIQPS 1087
+DVND+ P F K+ NF T R+ D D D+ G A++ Y+I
Sbjct: 1378 RDVNDNLPQFLLKEISLNFTEHMTPGTERIR-LPDTVDQDYLDPLDGPAASVVCYYIVHG 1436
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN--------GXXXXXXXXXXXXX 1139
+ D F + P++ L+V ELDRE + Y L + A +
Sbjct: 1437 NEDGHFGLDPVSHDLTVEKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNLLKATV 1496
Query: 1140 XXXDVNDNSPKF 1151
D+NDNSP F
Sbjct: 1497 YINDINDNSPVF 1508
Score = 65.7 bits (153), Expect = 9e-09
Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 7/171 (4%)
Query: 222 DQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
D D G T R L +D ++ ++N + F + D + L V AS+
Sbjct: 428 DYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVVASE 487
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ + +T+ A++ + +LD NDN PEF Y I + EN+ G +LQ+ ATD D G G
Sbjct: 488 VESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGLFGT 547
Query: 341 FTYQLDDPKGAFS----IDPRSGWLTV--RNQTVLDREAHSSLRMKVYAKE 385
+ + G+ S +DP +G +T+ V DRE + V A++
Sbjct: 548 EGVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARD 598
Score = 65.7 bits (153), Expect = 9e-09
Identities = 61/220 (27%), Positives = 91/220 (41%), Gaps = 12/220 (5%)
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPI 218
HY V D+G + V L+ VLD + F Q K E P +
Sbjct: 590 HYLSVEARDNGG---RGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVV 646
Query: 219 HAIDQDL--GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL----QANTF 272
A D DL + + Y LI + F +D G L + + +D + + T
Sbjct: 647 EARDSDLEGSPNSAVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTI 706
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L ++A+ P TAQ V + + D+ND P F Y I I E+ P+G VL+V A D
Sbjct: 707 ALTIEAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMD 766
Query: 333 KDQG-ENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQTVLD 370
D N TY++ G F I +G +++ + LD
Sbjct: 767 GDGSFPNNHVTYRIQQGGDGRFVIGASTGEISITHGASLD 806
Score = 62.1 bits (144), Expect = 1e-07
Identities = 48/171 (28%), Positives = 74/171 (43%), Gaps = 10/171 (5%)
Query: 221 IDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
+ +D T++Y L +L +D G + + +D + L V+A+
Sbjct: 978 VAEDADQNKTVKYSLEGEKGVLELLHVDDETGEIVVRNRIDHEEYSWLN-----FSVRAA 1032
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + + V +++LD NDN P F + + EN G + ++A D D G+ G
Sbjct: 1033 DTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFG 1092
Query: 340 EFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
TY LD K FSIDP G L V LDRE + + V A + P
Sbjct: 1093 RITYILDRVSSKEKFSIDPEKGILRVAG--ALDREETAEYMLAVEAWDNYP 1141
Score = 58.4 bits (135), Expect = 1e-06
Identities = 123/476 (25%), Positives = 195/476 (40%), Gaps = 65/476 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P G + L A+D D G GQ+ Y YI LS E F I+ +G
Sbjct: 179 VAEDSPPGI-LTTLEAVDKDEGAYGQVVY------YI--QGLS----EENNVFSISTSNG 225
Query: 1000 HVIV--ARSLPPESE--FRLNISALDG---GNLNDNIS-VRVFVKDVNDHFPVFKKTWYN 1051
+V AR+L E + + +N+ A+D G +N + + V VKDV D P F T
Sbjct: 226 KGVVRLARALDYERQHFYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEFLVTQPV 285
Query: 1052 FNV-EEAQYTRRV------LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
+ E+A V L V A D D G N + Y I + ++L FEI L G L
Sbjct: 286 VRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNRIIYGISNNGSEL-FEIDRLKGSLRT 344
Query: 1105 NGELDRETEDK-----YILTVVA-RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
+LDRE +IL VVA ++ DVND P+F +
Sbjct: 345 KQKLDREDSTNPINGAFILEVVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYEC 404
Query: 1159 E-WKHPEADELSNHNFESVMMI--------PVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
E ++ + + L+ S+ + ++ ++ + I + K N+ F
Sbjct: 405 EIGENAQENTLARFIDGSINEVFDYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATF--- 461
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK----PVFISRYYELE 1265
G + S+ + + L L ++S + V + D+ P F YE++
Sbjct: 462 GLRVKDPSMLDYERVRELSLTVVASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEID 521
Query: 1266 IEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV-IDPRNGTLYLVRSPDRE 1324
+ ENV A L+ L T+ + N T +F+ +DP GT+ L+ S +
Sbjct: 522 VPENVTAGTVLLQLQATDSDSGLFGTEGVRYANLTGSISSFLHLDPHAGTVTLMAS-ESP 580
Query: 1325 VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
V D E+I QK H + A D + V +++ + DVNDN+P F
Sbjct: 581 VFDR-EII-----QK------HYLSVEARDNGGRGNRNTVPLILNVLDVNDNAPVF 624
Score = 58.0 bits (134), Expect = 2e-06
Identities = 55/181 (30%), Positives = 88/181 (48%), Gaps = 21/181 (11%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+HA D+D+G A +RY L GN RK FSLD G L L LD + Q + L
Sbjct: 1301 VHAYDEDVGENAIVRYRLKMDTMGNFRK-FSLDKETGELSLAASLDRE-----QQMMYDL 1354
Query: 275 QVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT-D 332
+++A P ++ + + + D+NDNLP+F + +++ E++ G +++ T D
Sbjct: 1355 RIEAYDQGIPTPLSSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVD 1414
Query: 333 KD-----QGENGEFT-YQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAK 384
+D G Y + + G F +DP S LTV + LDRE S ++ + A
Sbjct: 1415 QDYLDPLDGPAASVVCYYIVHGNEDGHFGLDPVSHDLTVEKE--LDREKKSLYKLHIKAT 1472
Query: 385 E 385
E
Sbjct: 1473 E 1473
Score = 54.0 bits (124), Expect = 3e-05
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ--- 289
Y ++ GN+ F LD V+ L +EKELD + + + + + + + N L T
Sbjct: 1431 YYIVHGNEDGHFGLDPVSHDLTVEKELDREKKSLYKLHIKATE-ECTNANLSLDTTSHSG 1489
Query: 290 --ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ + + D+NDN P FE + I + G ++LQ+ ATD+D G NG Y
Sbjct: 1490 NLLKATVYINDINDNSPVFESKIFTGGISTSSLFGATILQLQATDEDDGLNGLVRY 1545
Score = 52.8 bits (121), Expect = 7e-05
Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN--ISIVENLPNGF 323
NL N + L++ S L TA+ V+I + D ND+ P F V N + + EN G
Sbjct: 1238 NLHGN-YTLELIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGK 1296
Query: 324 SVLQVMATDKDQGENGEFTYQLD-DPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
QV A D+D GEN Y+L D G FS+D +G L++ +++ LR+
Sbjct: 1297 PFFQVHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRI 1356
Query: 380 KVY 382
+ Y
Sbjct: 1357 EAY 1359
Score = 50.0 bits (114), Expect = 5e-04
Identities = 129/568 (22%), Positives = 221/568 (38%), Gaps = 71/568 (12%)
Query: 615 EEGVPFAVEERSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT---VHVVDV 669
EE F++ +G V+ + L + Y +A+ I T V V DV
Sbjct: 213 EENNVFSISTSNGKGVVRLARALDYERQHFYHINVLAVDRAIQGRINTGTAALLVRVKDV 272
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT--NMSSIYGNGTGNVRFLIANQQDVT 727
D+ L P++ ++ G + + ++ + ++ G+ N R + + +
Sbjct: 273 EDQPPEFL--VTQPVVRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNRIIYGISNNGS 330
Query: 728 DDIAIAE-DGTIFTQKPLDREK-----RDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDE 780
+ I G++ T++ LDRE + + V+A E +K + + ++T+ + D
Sbjct: 331 ELFEIDRLKGSLRTKQKLDREDSTNPINGAFILEVVAIEESKLQPAPSSTMEITVIVTDV 390
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
ND P F YE I EN A E T A F + G E+FD D
Sbjct: 391 NDEIPRFRSDGYECEIGEN-----------------AQENTLARF---IDGSINEVFDYD 430
Query: 841 EN-TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ G + SL I + A +EA + + D + ++ ++ E
Sbjct: 431 QGKNGTFRL---SLHPPSDIFEVIPKRA------INEATFGLRVKDPS--MLDYERVREL 479
Query: 900 SKVRIHRETKLNG---TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL 956
S + E + G TA ++ + + F + Q +PEN+ GT +++L A
Sbjct: 480 SLTVVASEVESAGRTSTAQIRVVVLDQNDNFP-EFSQPVYEIDVPENVTAGTVLLQLQAT 538
Query: 957 DLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN 1016
D DSGL G + + S L D + +E + R + + L+
Sbjct: 539 DSDSGLFGTEGVRYANLTGSISSFLHLDPHAGTVTLMASESP---VFDREII--QKHYLS 593
Query: 1017 ISALD-GGNLNDN-ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
+ A D GG N N + + + V DVND+ PVF + Y ++E + V+A D+D
Sbjct: 594 VEARDNGGRGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDL 653
Query: 1075 --GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK---------YILTVVAR 1123
N+ + Y + + F + TG LSV +D E + LT+ A
Sbjct: 654 EGSPNSAVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAA 713
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D G DVND +P F
Sbjct: 714 DGG-EPPLTAQVEVTVYVQDVNDYAPVF 740
Score = 47.2 bits (107), Expect = 0.003
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L I A DGG L + V V+V+DVND+ PVF ++ Y + E + + +V A D
Sbjct: 708 LTIEAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDG 767
Query: 1073 DFG-QNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
D N ++TY IQ D F I TG +S+
Sbjct: 768 DGSFPNNHVTYRIQQGG-DGRFVIGASTGEISI 799
Score = 46.0 bits (104), Expect = 0.008
Identities = 17/37 (45%), Positives = 28/37 (75%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
++A + VTVY++DVND P+FL++ Y + + E TP+G
Sbjct: 720 LTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSG 756
Score = 44.8 bits (101), Expect = 0.018
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQ 275
I A D D G + Y L + ++ FS+D G L + LD + AE+ L +
Sbjct: 1081 ILAKDLDSGDFGRITYILDRVSSKEKFSIDPEKGILRVAGALDREETAEYMLAVEAWD-N 1139
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
LN + A + I +LD NDN+P + I E ++++ ATD D
Sbjct: 1140 YPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLRATDADD 1199
Query: 336 --GENGEFTYQLDDPKGAFSI 354
NG+ ++ + DP G F I
Sbjct: 1200 PTNGNGQLSFDIVDPSGIFYI 1220
Score = 43.6 bits (98), Expect = 0.043
Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 22/219 (10%)
Query: 941 PENIPIGTTIIKLNALDLDSG-LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
PE P+GT I +L D D L ++ +S + S++A + + E
Sbjct: 75 PET-PVGTLIYRLRGYDADGDPLTFGVQKSADSHIIRLKQNTSSEAFVYLNHELDRE--- 130
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVF---VKDVNDHFPVFKKTWYNFNVEE 1056
AR E+ L ++ DG N + F V+D+ND+ P+FK V E
Sbjct: 131 ----ARE-----EYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAE 181
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISPLT--GVLSVNGELDRETE 1113
+L ++A D D G + Y+IQ S+ + F IS GV+ + LD E +
Sbjct: 182 -DSPPGILTTLEAVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARALDYERQ 240
Query: 1114 DKYILTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y + V+A D DV D P+F
Sbjct: 241 HFYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEF 279
Score = 42.7 bits (96), Expect = 0.075
Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 8/134 (5%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
++L ELD +A T +L + +L Q+ + + + D+NDN P F+
Sbjct: 121 VYLNHELDREAREEY---TLILTLTDGRLGEGNFVTQSFLLL-VEDINDNEPIFKPFASV 176
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQ---LDDPKGAFSIDPRSGWLTVRNQTVL 369
+ + E+ P G + + A DKD+G G+ Y L + FSI +G VR L
Sbjct: 177 LEVAEDSPPGI-LTTLEAVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARAL 235
Query: 370 DREAHSSLRMKVYA 383
D E + V A
Sbjct: 236 DYERQHFYHINVLA 249
Score = 41.1 bits (92), Expect = 0.23
Identities = 48/180 (26%), Positives = 81/180 (45%), Gaps = 22/180 (12%)
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV---NAPVELVSLNLT-EHYENFK 1289
+T L++ V DV D PVF+ + YE+ ++EN +P+ + + + E N
Sbjct: 606 NTVPLILNVLDVNDNA-----PVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSA 660
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIY 1349
+ Y ++ + +D F +D R G L + RE D +E + + +R + I
Sbjct: 661 VEYRLIGAHHSDY---FHVDRRTGRLSV-----REAVD-FERLESSGGSGDTRTIALTIE 711
Query: 1350 PVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIG 1409
A D E V+V V ++DVND +P F +V IP P G V+++ G
Sbjct: 712 --AADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIV--IPEDTPSGLPVLRVTAMDG 767
Score = 35.9 bits (79), Expect = 8.6
Identities = 18/56 (32%), Positives = 24/56 (42%)
Query: 1104 VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
+N ELDRE ++Y L + D D+NDN P F F +LE
Sbjct: 123 LNHELDREAREEYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLE 178
>UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor
constant; n=6; Clupeocephala|Rep: Cadherin-related
neuronal receptor constant - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 1009
Score = 109 bits (261), Expect = 8e-22
Identities = 128/491 (26%), Positives = 199/491 (40%), Gaps = 36/491 (7%)
Query: 426 GTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV 485
GT T +++ E +V+V +LDANDN+P+F P + Y+ + A+ G A
Sbjct: 102 GTCTLSLDVVLESPFEQHSVDVEILDANDNSPLF-PRDEYQLEISEGAQPGARFSIEGAQ 160
Query: 486 DPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQP 542
D D N + Y L +L + S V + P L H + A+D
Sbjct: 161 DSDDASNSVRHYRLTPNEHLALDSTKPPADGKQVELVLKKPFDRELLQSHQFLITATDGG 220
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
+ P R A + + V T N +P F + Y+ + N +G V ++ D E
Sbjct: 221 SPP---RSGTARINVRVL-DTNDN---VPVFDSSVYKVKLRENSPVGALVIKLNATDRDE 273
Query: 603 --QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LS 657
+V Y + V F+V+ SG I V ++ Y+ A ++
Sbjct: 274 GSNGEVYYSFSSYTPDKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRGQGAVA 333
Query: 658 IVTNATVHVVDVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+ V V+DVND ++L SP V+E++ + + N +G
Sbjct: 334 VHCKVVVEVLDVNDNPPEIVLSSLSSP----VREDARADTVVALISINDKD---SGQNKQ 386
Query: 717 RFLIANQQDVTDDI-AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
L D+ I + TI T LDRE Y +TV A + G + V +
Sbjct: 387 VSLDIIPPDLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTAT-DGGTPPLSSSMTVRV 445
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ D NDNPP F+ +Y ++ EN+ + +IKATD D G NA YT+ +
Sbjct: 446 EVADINDNPPRFKQTSYTVYVSENNAPSAPL---CVIKATDPDAGENARITYTILTDNNH 502
Query: 836 MFDVDENTGVVKFIGD-----SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEND 888
V V G+ S D EK + + A+D G LS A + I I D ND
Sbjct: 503 GVSVGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQDNGVPPLSRVATVYIYIMDSND 562
Query: 889 NKPEFNQIEEN 899
+ P+F + N
Sbjct: 563 HSPQFARAVAN 573
Score = 99 bits (238), Expect = 5e-19
Identities = 109/456 (23%), Positives = 193/456 (42%), Gaps = 37/456 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LD NDN PVF S++Y+ ++ N+ VG ++ K+ A D D G NG V Y +
Sbjct: 230 INVRVLDTNDNVPVF-DSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTP 288
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ F ++ ++G + V + E + ++++A+D+ + V ++V
Sbjct: 289 DKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVN-- 346
Query: 563 TKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGYEEGVP 619
N P+I + +P V + T V I +ND + + VS D++ +P
Sbjct: 347 --DNPPEIVLSSLSSP----VREDARADTVVALISINDKDSGQNKQVSLDII---PPDLP 397
Query: 620 FAVEERSGVITVVDD--LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVL 676
F ++ T+V L R Y+ A LS V V D+ND
Sbjct: 398 FKIKSFRNHYTIVTSALLDRETISSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRF 457
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA--- 733
+ +++ +V EN+A +A + N L N V+ ++
Sbjct: 458 KQTSYT---VYVSENNAPSAPLCVIKATDPDAGENARITYTILTDNNHGVSVGSYVSVKP 514
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G ++ + D EK + V A+ N GV + + V IYI D ND+ P F A
Sbjct: 515 ATGEVYALRSFDFEKLREFHFQVKAQDN-GVPPLSRVATVYIYIMDSNDHSPQFARAVAN 573
Query: 794 G-----FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVK 847
G I+ +S+ G + A D D G NA +Y L + ++F + E+TG ++
Sbjct: 574 GSHSTETILRHSEAGVLVSR---ALAWDLDAGENAWLLYNLHHAPELDLFKIHEHTGEIR 630
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
++ + ++ L++ RD G + A I +
Sbjct: 631 TTRRVIE-DNSTVFSLTVHVRDHGSPARSASTTINV 665
Score = 86.6 bits (205), Expect = 5e-15
Identities = 68/216 (31%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P+G +IKLNA D D G NG++ Y F+S Y P +V++ F ++ G +
Sbjct: 255 ENSPVGALVIKLNATDRDEGSNGEVYYSFSS--YTPD--------KVRQMFSVDADSGEI 304
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V ++ E + + + I A D G + + V V V DVND+ P + + V E
Sbjct: 305 RVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVRED 364
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG--VLSVNGELDRETEDK 1115
V+ + D D GQN ++ I P DLPF+I + + LDRET
Sbjct: 365 ARADTVVALISINDKDSGQNKQVSLDIIP--PDLPFKIKSFRNHYTIVTSALLDRETISS 422
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y +TV A D G D+NDN P+F
Sbjct: 423 YNVTVTATDGG-TPPLSSSMTVRVEVADINDNPPRF 457
Score = 77.8 bits (183), Expect = 2e-12
Identities = 61/225 (27%), Positives = 108/225 (48%), Gaps = 16/225 (7%)
Query: 690 ENSAGAAIGQIFHTNMSSIYGNGTGNVRF--LIANQQDVTDDIAIAEDGT---IFTQKPL 744
E S GA G F + + + +VR L N+ D DG + +KP
Sbjct: 143 EISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGKQVELVLKKPF 202
Query: 745 DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
DRE ++ + A + G +G ++ + + D NDN PVF+ + Y+ + ENS +G
Sbjct: 203 DRELLQSHQFLITAT-DGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVKLRENSPVGA 261
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFIGDSLDREKKIM 860
+ + ATD DEG+N Y+ + ++MF VD ++G ++ + ++D E+
Sbjct: 262 LVIK---LNATDRDEGSNGEVYYSFSSYTPDKVRQMFSVDADSGEIR-VKSNVDYEETNS 317
Query: 861 YKLSLVARD--TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
Y++ + A D G ++ ++++ + D NDN PE +S VR
Sbjct: 318 YEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVR 362
Score = 75.4 bits (177), Expect = 1e-11
Identities = 47/150 (31%), Positives = 78/150 (52%), Gaps = 12/150 (8%)
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D L L+K D + LQ++ F+ + A+ +P ++ AR+ + +LD NDN+P F
Sbjct: 190 DGKQVELVLKKPFDREL---LQSHQFL--ITATDGGSPPRSGTARINVRVLDTNDNVPVF 244
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWL 361
+ Y + + EN P G V+++ ATD+D+G NGE Y D + FS+D SG +
Sbjct: 245 DSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKVRQMFSVDADSGEI 304
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
V++ +D E +S M + A + V
Sbjct: 305 RVKSN--VDYEETNSYEMYIQAADRGQGAV 332
Score = 70.1 bits (164), Expect = 4e-10
Identities = 62/221 (28%), Positives = 97/221 (43%), Gaps = 23/221 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ T + ++ D DSG N Q+ + IPP ++K + H
Sbjct: 361 VREDARADTVVALISINDKDSGQNKQVSLDI-----IPPDL----PFKIKSF----RNHY 407
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ + L E S + + ++A DGG L+ +++VRV V D+ND+ P FK+T Y V
Sbjct: 408 TIVTSALLDRETISSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVS 467
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-----TDLPFEISPLTGVLSVNGELDR 1110
E L + ATD D G+NA +TY I + + P TG + D
Sbjct: 468 ENNAPSAPLCVIKATDPDAGENARITYTILTDNNHGVSVGSYVSVKPATGEVYALRSFDF 527
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E ++ V A+DNG D ND+SP+F
Sbjct: 528 EKLREFHFQVKAQDNG-VPPLSRVATVYIYIMDSNDHSPQF 567
Score = 69.3 bits (162), Expect = 8e-10
Identities = 81/339 (23%), Positives = 139/339 (41%), Gaps = 31/339 (9%)
Query: 1017 ISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
I+A DGG+ + + R+ V+ D ND+ PVF + Y + E ++ K++ATD D
Sbjct: 214 ITATDGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVKLRENSPVGALVIKLNATDRDE 273
Query: 1075 GQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
G N + Y P F + +G + V +D E + Y + + A D G
Sbjct: 274 GSNGEVYYSFSSYTPDKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRG-QGAV 332
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
DVNDN P+ L P ++ V +I + +N
Sbjct: 333 AVHCKVVVEVLDVNDNPPEIV----LSSLSSPVREDARADTV--VALISINDKDSGQNKQ 386
Query: 1192 IGTTV--------AKVFANDTDFIGNG--NGLILYSLPQRKNQQNLGLPSLSSTAILMVT 1241
+ + K F N + + + + S + G P LSS+ + V
Sbjct: 387 VSLDIIPPDLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTATDGGTPPLSSSMTVRVE 446
Query: 1242 VADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNEND 1299
VAD+ D + P F Y + + EN +AP+ ++ + EN ++ Y IL +N+
Sbjct: 447 VADIND-----NPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAGENARITYTILTDNN 501
Query: 1300 TDIR-RTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ ++V + P G +Y +RS D E + V+A+
Sbjct: 502 HGVSVGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQ 540
Score = 66.5 bits (155), Expect = 5e-09
Identities = 43/171 (25%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D+D G + Y S R++FS+D+ +G + ++ +D + + N++ +
Sbjct: 266 LNATDRDEGSNGEVYYSFSSYTPDKVRQMFSVDADSGEIRVKSNVDYE-----ETNSYEM 320
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+QA+ +V +E+LD+NDN PE + + + E+ V + DKD
Sbjct: 321 YIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTVVALISINDKD 380
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+N + + + P F I T+ +LDRE SS + V A +
Sbjct: 381 SGQNKQVSLDIIPPDLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTATD 431
Score = 52.0 bits (119), Expect = 1e-04
Identities = 60/274 (21%), Positives = 110/274 (40%), Gaps = 18/274 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF- 141
+ V + D NDNVP+F + Y V + E +P G A + + V + +
Sbjct: 230 INVRVLDTNDNVPVFDSSVYKVKLRENSPVG--ALVIKLNATDRDEGSNGEVYYSFSSYT 287
Query: 142 ----KDIRAFDRDKPNTP-NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD--YDAGD 194
+ + + D D S+V Y + + A + V + KV+ D D
Sbjct: 288 PDKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVND 347
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSLDSVNG 251
++V+ + + ++ + I D+D G + ++I + F + S
Sbjct: 348 NPPEIVLSSLSSPVREDARADTVVALISINDKDSGQNKQVSLDIIPPD--LPFKIKSFRN 405
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
+ LD E +++ + V A+ P ++ V +E+ D+NDN P F+ Y
Sbjct: 406 HYTIVTSALLDRE---TISSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSY 462
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ + EN + + ATD D GEN TY +
Sbjct: 463 TVYVSENNAPSAPLCVIKATDPDAGENARITYTI 496
Score = 50.8 bits (116), Expect = 3e-04
Identities = 51/197 (25%), Positives = 82/197 (41%), Gaps = 19/197 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN + + A D D+G N +I Y ++ + + V Y + G
Sbjct: 466 VSENNAPSAPLCVIKATDPDAGENARITYTILTD--------NNHGVSVGSYVSVKPATG 517
Query: 1000 HVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V RS E EF + A D G L+ +V +++ D NDH P F + N +
Sbjct: 518 EVYALRSFDFEKLREFHFQVKAQDNGVPPLSRVATVYIYIMDSNDHSPQFARAVANGSHS 577
Query: 1056 EAQYTRR-----VLGKVDATDADFGQNANLTYFIQPS-DTDLPFEISPLTGVLSVNGELD 1109
R ++ + A D D G+NA L Y + + + DL F+I TG + +
Sbjct: 578 TETILRHSEAGVLVSRALAWDLDAGENAWLLYNLHHAPELDL-FKIHEHTGEIRTTRRVI 636
Query: 1110 RETEDKYILTVVARDNG 1126
+ + LTV RD+G
Sbjct: 637 EDNSTVFSLTVHVRDHG 653
Score = 44.4 bits (100), Expect = 0.024
Identities = 45/176 (25%), Positives = 73/176 (41%), Gaps = 17/176 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
I A D D G A + Y +++ N+ + S+ G ++ + D + + F
Sbjct: 479 IKATDPDAGENARITYTILTDNNHGVSVGSYVSVKPATGEVYALRSFDFE-----KLREF 533
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-----IVENLPNGFSVLQ 327
QV+A P + A V I ++D ND+ P+F N S I+ + G V +
Sbjct: 534 HFQVKAQDNGVPPLSRVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVSR 593
Query: 328 VMATDKDQGENGEFTYQLDD-PK-GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+A D D GEN Y L P+ F I +G + + + D SL + V
Sbjct: 594 ALAWDLDAGENAWLLYNLHHAPELDLFKIHEHTGEIRTTRRVIEDNSTVFSLTVHV 649
Score = 43.2 bits (97), Expect = 0.056
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
R + S R+ F+++ G L + +D + + T L + L +P + Q
Sbjct: 65 RIRISSDTARRYFNINHKTGKLVISDRIDRETLCEF-SGTCTLSLDVV-LESPFE--QHS 120
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
V++E+LD NDN P F D Y + I E G A D D N Y+L
Sbjct: 121 VDVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRL 174
Score = 40.7 bits (91), Expect = 0.30
Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 14/182 (7%)
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPES--EFR----LNISALDGGNLNDNISVRV 1033
++S+D +RYF IN + G ++++ + E+ EF L++ + + SV V
Sbjct: 67 RISSDT--ARRYFNINHKTGKLVISDRIDRETLCEFSGTCTLSLDVVLESPFEQH-SVDV 123
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-TDLP 1092
+ D ND+ P+F + Y + E A D+D N+ Y + P++ L
Sbjct: 124 EILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALD 183
Query: 1093 FEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
P G L + DRE + + A D G D NDN P
Sbjct: 184 STKPPADGKQVELVLKKPFDRELLQSHQFLITATDGG-SPPRSGTARINVRVLDTNDNVP 242
Query: 1150 KF 1151
F
Sbjct: 243 VF 244
Score = 39.5 bits (88), Expect = 0.69
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 13/128 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF---VPSNLYEF-SMKSNAKVGTVIGKVKAVDPDLGQNGM 494
L V + ++D+ND++P F V + + ++ +++ G ++ + A D D G+N
Sbjct: 547 LSRVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVSRALAWDLDAGENAW 606
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF-----VEASDQPANPSERR 549
+LY+L L + FKI+ +TG + ++E +F V PA +
Sbjct: 607 LLYNLHHAPELDL---FKIHEHTGEIRTTRR-VIEDNSTVFSLTVHVRDHGSPARSASTT 662
Query: 550 YSLAVVTI 557
++AV+ +
Sbjct: 663 INVAVMEL 670
>UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Rep:
Protocadherin alpha - Macaca fuscata (Japanese macaque)
Length = 937
Score = 109 bits (261), Expect = 8e-22
Identities = 120/425 (28%), Positives = 177/425 (41%), Gaps = 56/425 (13%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++G +F +DRE+ V ++ V + ++D NDNPPVF
Sbjct: 80 QNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQKN 139
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
FI E+ + + ++ A+DAD G NAL Y L E F +D T
Sbjct: 140 LFIAESRPLDSRFPLEG---ASDADIGENALLTYRL--SPNEYFSLDVPTS--------- 185
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+++ K L LV R EL +++ + KPE L GT
Sbjct: 186 NQQVK---PLGLVLRKPLDREETPELHLLLTATDGGKPE-----------------LTGT 225
Query: 914 AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
+I V N A D+ +PEN+ IGT +I NA DLD GLNG I Y F+S+
Sbjct: 226 VQL-LITVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD 284
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNI 1029
V + ++K F ++ G + V + E ++ + A+D G L +
Sbjct: 285 V----------SPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHC 334
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V V DVND+ P T + E V+ + D DFG N +T + P
Sbjct: 335 TVLVEVVDVNDNAPQLTLTSLFLPISEDAQPGTVITLISVFDRDFGVNGQVTCSLTP--- 391
Query: 1090 DLPFE-ISPLTGVLS--VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+PF+ +S S ++ LDRE+ Y L V ARD G DVND
Sbjct: 392 HVPFKLVSTFKNYYSLVLDSVLDRESVSAYELVVTARDGG-SPSLWATASVSVEVADVND 450
Query: 1147 NSPKF 1151
N+P F
Sbjct: 451 NAPAF 455
Score = 84.6 bits (200), Expect = 2e-14
Identities = 99/405 (24%), Positives = 172/405 (42%), Gaps = 31/405 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V + +T+LD NDN PVF LY + N +GT++ A D D G NG ++Y
Sbjct: 221 ELTGTVQLLITVLDVNDNAPVF-DRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIY 279
Query: 498 DLQRTSNLTITSPFKINPNTGTVSV-AESPILEGR-HALFVEASDQPANPSERRYSLAVV 555
+ I S F ++P +G ++V E R H + VEA D+ P ++ V
Sbjct: 280 SFSSDVSPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVE 339
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++V + P + + GT + I V D V+ +
Sbjct: 340 VVDVN-------DNAPQLTLTSLFLPISEDAQPGTVITLISVFD--RDFGVNGQVTCSLT 390
Query: 616 EGVPFAVEE--RSGVITVVDD-LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
VPF + ++ V+D L R + Y+ A + +L + +V V DVND
Sbjct: 391 PHVPFKLVSTFKNYYSLVLDSVLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVND 450
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN----QQDVT 727
+ ++ +F VKEN+ IF + V + + ++ ++
Sbjct: 451 NAPAFTQSEYT--VF-VKENNPPGC--HIFTVSARDADAQENALVSYSLVERRVGERALS 505
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+++ AE G ++ +PLD E+ ++ + V A + GV S + + +++ DENDN PV
Sbjct: 506 SYVSVHAESGKVYALQPLDHEELELLQFQVSAR-DAGVPSLSSNATLQVFVLDENDNAPV 564
Query: 787 FEHATYEGFIMENSK-IGTEIKMDNI---IKATDADEGTNALFMY 827
G S+ + + ++ ++A DAD G NA Y
Sbjct: 565 LLAPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Score = 81.8 bits (193), Expect = 1e-13
Identities = 117/479 (24%), Positives = 181/479 (37%), Gaps = 38/479 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E ++ + +V+V + D NDN PVF P+ + + + + A D D+G
Sbjct: 105 HLEVIVDRPLQVFHVDVEVKDINDNPPVF-PATQKNLFIAESRPLDSRFPLEGASDADIG 163
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSE 547
+N ++ Y L ++ P V P+ L + A+D
Sbjct: 164 ENALLTYRLSPNEYFSLDVPTSNQQVKPLGLVLRKPLDREETPELHLLLTATDGGKPELT 223
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
L + ++V + P F Y + NV IGT V +D E D
Sbjct: 224 GTVQLLITVLDVN-------DNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGD 276
Query: 606 VSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
+ Y + F ++ SG ITV+ + + A+ + L + + T
Sbjct: 277 IIYSFSSDVSPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGF-LPLAGHCT 335
Query: 664 V--HVVDVNDERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
V VVDVND L L PI + + I +F + G V +
Sbjct: 336 VLVEVVDVNDNAPQLTLTSLFLPISEDAQPGTVITLIS-VFDRDFGV-----NGQVTCSL 389
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
++ LDRE Y + V A + G S V++ + D
Sbjct: 390 TPHVPFKLVSTFKNYYSLVLDSVLDRESVSAYELVVTAR-DGGSPSLWATASVSVEVADV 448
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEG--K 834
NDN P F + Y F+ EN+ G I + A DAD NAL Y+L GE
Sbjct: 449 NDNAPAFTQSEYTVFVKENNPPGCHI---FTVSARDADAQENALVSYSLVERRVGERALS 505
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
V +G V + LD E+ + + + ARD G LSS A L + + DENDN P
Sbjct: 506 SYVSVHAESGKV-YALQPLDHEELELLQFQVSARDAGVPSLSSNATLQVFVLDENDNAP 563
Score = 64.5 bits (150), Expect = 2e-08
Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS-------LFLEKELDLDAEHNLQANTF 272
A D D+G A L Y L + + FSLD + L L K LD + L
Sbjct: 157 ASDADIGENALLTYRL---SPNEYFSLDVPTSNQQVKPLGLVLRKPLDREETPELH---- 209
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L + A+ P T ++ I +LD+NDN P F+ Y + + EN+ G V+ A+D
Sbjct: 210 -LLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASD 268
Query: 333 KDQGENGEFTYQLD-----DPKGAFSIDPRSGWLTV 363
D+G NG+ Y D K F +DP SG +TV
Sbjct: 269 LDEGLNGDIIYSFSSDVSPDIKSKFHMDPVSGAITV 304
Score = 61.7 bits (143), Expect = 2e-07
Identities = 76/293 (25%), Positives = 116/293 (39%), Gaps = 24/293 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L G +++ + + + + DVNDN P+F T Y V + E G + +
Sbjct: 212 LTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDE 271
Query: 127 SLTIPLTVPRGLTIFKDIRA-FDRDKPNTP----------NSDVHYSIVSGNDDGHFALE 175
L + + DI++ F D + S H V D G L
Sbjct: 272 GLNGDIIYSFSSDVSPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFLPL- 330
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLR 232
+ H VL+ +V+D + D QL + + I ++ I I D+D GV +
Sbjct: 331 AGHCTVLV--EVVDVN--DNAPQLTLTSLFLPISEDAQPGTVITLISVFDRDFGVNGQVT 386
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
L KL S SL L+ LD ++ + + L V A +P A A V
Sbjct: 387 CSLTPHVPFKLVSTFKNYYSLVLDSVLDRES-----VSAYELVVTARDGGSPSLWATASV 441
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+E+ D+NDN P F Y + + EN P G + V A D D EN +Y L
Sbjct: 442 SVEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
Score = 60.1 bits (139), Expect = 5e-07
Identities = 81/344 (23%), Positives = 146/344 (42%), Gaps = 41/344 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPT--------------GEKAFIFLIAPIGPSL 128
V V ++D+NDN P+F T ++ + E P GE A L + P+
Sbjct: 119 VDVEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENAL--LTYRLSPNE 176
Query: 129 TIPLTVPRGLTIFKDIRAFDR---DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
L VP K + R D+ TP ++H +++ D G L + V LL
Sbjct: 177 YFSLDVPTSNQQVKPLGLVLRKPLDREETP--ELHL-LLTATDGGKPELTGT---VQLLI 230
Query: 186 KVLDYDAG----DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL---ISG 238
VLD + D+ V + I ++ P +A D D G+ + Y +S
Sbjct: 231 TVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHP---NASDLDEGLNGDIIYSFSSDVSP 287
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+ + F +D V+G++ + +D + ++ + V+A V +E++D
Sbjct: 288 DIKSKFHMDPVSGAITVIGHMDFE-----ESRAHKIPVEAVDKGFLPLAGHCTVLVEVVD 342
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
+NDN P+ + + I E+ G + + D+D G NG+ T L +
Sbjct: 343 VNDNAPQLTLTSLFLPISEDAQPGTVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFK 402
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIA 401
+ ++ +VLDRE+ S+ + V A++ +PS+ T + S +A
Sbjct: 403 NYYSLVLDSVLDRESVSAYELVVTARDGGSPSLWATASVSVEVA 446
Score = 59.3 bits (137), Expect = 8e-07
Identities = 62/221 (28%), Positives = 93/221 (42%), Gaps = 21/221 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV N A Q + EN P G I ++A D D+ N + Y E +
Sbjct: 443 VEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL-VERRVGE 501
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVF 1034
LS+ Y ++ G V + L E + +SA D G +L+ N +++VF
Sbjct: 502 RALSS-------YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPSLSSNATLQVF 554
Query: 1035 VKDVNDHFPVFKKTWY-------NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP- 1086
V D ND+ PV + V + V+ KV A DAD G NA L+Y QP
Sbjct: 555 VLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEFQPV 614
Query: 1087 -SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+PF + TG +S L ++ L V+ +D+G
Sbjct: 615 AVSARIPFRVGLYTGEISTTRALGETDAPRHRLLVLVKDHG 655
Score = 54.4 bits (125), Expect = 2e-05
Identities = 66/242 (27%), Positives = 104/242 (42%), Gaps = 20/242 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+ V+DVND V + ++ + EN + + + H N S + G++ + ++
Sbjct: 230 ITVLDVNDNAPVFDRTLYT---VKLPENVSIGTL--VIHPNASDLDEGLNGDIIYSFSS- 283
Query: 724 QDVTDDIAIA-----EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
DV+ DI G I +D E+ +++ V A +KG + AG V + +
Sbjct: 284 -DVSPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEA-VDKGFLPLAGHCTVLVEVV 341
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
D NDN P + I E+++ GT I +I D D G N +L
Sbjct: 342 DVNDNAPQLTLTSLFLPISEDAQPGTVI---TLISVFDRDFGVNGQVTCSLTPHVPFKL- 397
Query: 839 VDENTGVVKFIGDS-LDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQ 895
V + DS LDRE Y+L + ARD G S + A + + + D NDN P F Q
Sbjct: 398 VSTFKNYYSLVLDSVLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFTQ 457
Query: 896 IE 897
E
Sbjct: 458 SE 459
Score = 54.4 bits (125), Expect = 2e-05
Identities = 72/244 (29%), Positives = 105/244 (43%), Gaps = 21/244 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
++EV N A + L LFL I E+ GT I ++ D D G+NGQ+ V
Sbjct: 337 LVEVVDVNDNAPQLT-LTSLFLPISEDAQPGTVITLISVFDRDFGVNGQVTCSLTPHV-- 393
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVF 1034
P KL + K Y+ + V+ S+ S + L ++A DGG +L SV V
Sbjct: 394 -PFKLVS---TFKNYYSL--VLDSVLDRESV---SAYELVVTARDGGSPSLWATASVSVE 444
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDL 1091
V DVND+ P F ++ Y V+E + V A DAD +NA ++Y + + + L
Sbjct: 445 VADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERAL 504
Query: 1092 PFEIS--PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+S +G + LD E + V ARD G D NDN+P
Sbjct: 505 SSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG-VPSLSSNATLQVFVLDENDNAP 563
Query: 1150 KFYA 1153
A
Sbjct: 564 VLLA 567
Score = 47.6 bits (108), Expect = 0.003
Identities = 48/158 (30%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQARVEIELLDLND 301
L ++ NG LF+ +D + A + L+V ++ PL+ V++E+ D+ND
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVI---VDRPLQVFH--VDVEVKDIND 128
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID-PRSGW 360
N P F N+ I E+ P A+D D GEN TY+L P FS+D P S
Sbjct: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRL-SPNEYFSLDVPTSNQ 187
Query: 361 ----LTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
L + + LDRE L + + A + P + GT
Sbjct: 188 QVKPLGLVLRKPLDREETPELHLLLTATDGGKPELTGT 225
Score = 47.2 bits (107), Expect = 0.003
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 24/156 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P L+ T L++TV DV D + PVF Y +++ ENV+ ++ N ++ E
Sbjct: 218 GKPELTGTVQLLITVLDVND-----NAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEG 272
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N + Y ++ DI+ F +DP +G + ++ D E +++ V A + + LP
Sbjct: 273 LNGDIIYSFSSDVSPDIKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGF---LP 329
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
L G V+V + DVNDN+P+ T
Sbjct: 330 ----------LAG----HCTVLVEVVDVNDNAPQLT 351
Score = 44.0 bits (99), Expect = 0.032
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFS------MKSNAKVGTVIGKVKAVDPDLGQN 492
L S ++V +LD NDN PV + + + + G V+ KV+AVD D G N
Sbjct: 545 LSSNATLQVFVLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASDQPANPSERRY 550
+ Y+ Q + ++ PF++ TG +S A RH L V D PS
Sbjct: 605 AWLSYEFQPVA-VSARIPFRVGLYTGEISTTRALGETDAPRHRLLVLVKDH-GEPSLTAT 662
Query: 551 SLAVVTI 557
+ +V++
Sbjct: 663 ATVLVSL 669
Score = 37.5 bits (83), Expect = 2.8
Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 5/62 (8%)
Query: 1429 ERLSLNGLT-SPQATDSDIGINADIRYQILNEQAP----RFAIDPVSGTVRVVAALARDA 1483
E +S+ L P A+D D G+N DI Y ++ +P +F +DPVSG + V+ + +
Sbjct: 253 ENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPVSGAITVIGHMDFEE 312
Query: 1484 GR 1485
R
Sbjct: 313 SR 314
>UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 881
Score = 108 bits (260), Expect = 1e-21
Identities = 128/514 (24%), Positives = 221/514 (42%), Gaps = 44/514 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
++ ++VE+ + D ND+ P F P N + N +G+ A+D D+G+N +
Sbjct: 108 KEKFQLIHVEIEVKDINDHPPRF-PHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQS 166
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPIL-------EGRHALFVEASDQPANPSERR 549
Y++ +S+ + ++ + AE ++ E + + V A+D + R
Sbjct: 167 YNISPSSHFEV----EVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGGVHA---R 219
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
+V I+V + P F + + + +G V ++ D E +V+
Sbjct: 220 SGSMLVNIKVLDSNDNS----PSFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVNGEVT 275
Query: 608 YDLLHGY--EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH 665
Y L G+ E G F V+ +G +T+ + R +Y+ A AN S+ + VH
Sbjct: 276 YALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLYELVIKASDMGAN-SVPSTCKVH 334
Query: 666 --VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIAN 722
VVDVND + +P V + AA +S +G+ G VR +
Sbjct: 335 IDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSLLG 394
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ + A + I T LDRE+ Y +TV+AE + G + Q T+ ++DEND
Sbjct: 395 HEHFSLQQAYGDSFMIITTTALDRERIPEYNLTVVAE-DLGNPPFKTVRQYTVRVKDEND 453
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF------GEGKEM 836
NPP+F YE ++EN+ G+ + + A D D G NA Y + G
Sbjct: 454 NPPLFSKTLYEVSVLENNIPGSYV---TTVVARDPDVGENAKVSYKVLDAEVPGGSPVST 510
Query: 837 F-DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ VD ++G + + S D E L + A D G LSS + + I + D+NDN P F
Sbjct: 511 YVSVDSHSGSL-YTLRSFDYETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYF 569
Query: 894 N-QIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
+ +N + N AG+ + V +++
Sbjct: 570 TFPVLQNDSADV--PLPFNAPAGYLALRVSAEDE 601
Score = 87.4 bits (207), Expect = 3e-15
Identities = 114/473 (24%), Positives = 203/473 (42%), Gaps = 40/473 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +LD+NDN+P F S+L + ++ VG + +V A DPD G NG V Y L +
Sbjct: 225 VNIKVLDSNDNSPSFEHSSL-TVELDEDSPVGHRVLRVHAFDPDEGVNGEVTYALAAGFS 283
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPAN--PSERRYSLAVVTIEVT 560
+ F ++P TG V++ E R + L ++ASD AN PS + + VV +
Sbjct: 284 PEVGRLFHVDPYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDN 343
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV 618
KP P G + + V I +D ++ V LL G+E
Sbjct: 344 APEISIKPMTPGSDGVAS---ITEAAAADSFVALISTSDRDSGSNGYVRVSLL-GHEH-- 397
Query: 619 PFAVEERSG---VITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERG 674
F++++ G +I L R P Y+ VA N V TV V D ND
Sbjct: 398 -FSLQQAYGDSFMIITTTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPP 456
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL---IANQQDVTDDIA 731
+ K + + ++ N G+ + + + + N + + L + V+ ++
Sbjct: 457 LFSKTLYEVSV--LENNIPGSYVTTVVARD-PDVGENAKVSYKVLDAEVPGGSPVSTYVS 513
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ + G+++T + D E + + AE ++G S + + I + D+NDN P F
Sbjct: 514 VDSHSGSLYTLRSFDYETLQQIDLVIQAE-DRGSPSLSSTSTIRIKVVDQNDNYPYFTFP 572
Query: 791 TYEGFIME-----NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
+ + N+ G + + A D DEG N + + +F +F VD+++G
Sbjct: 573 VLQNDSADVPLPFNAPAG---YLALRVSAEDEDEGMNKVLSFQIFQGDTNLFRVDKDSGE 629
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
+ + L E + ++ + D G LSS A + ++ +D +P +Q+
Sbjct: 630 I-VLKQWLSAEIGDVLEIKISVSDNGRSPLSSSATIRFLV---SDTEPSADQV 678
Score = 80.6 bits (190), Expect = 3e-13
Identities = 87/327 (26%), Positives = 145/327 (44%), Gaps = 34/327 (10%)
Query: 588 IGTSVGQIRVN---DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN----- 639
+GT +G + + D + D S+ L+ V + E G+++V D + R
Sbjct: 36 LGTEIGNLSRDLKIDPADDPDTSFRLMQENNSSV-IQMREVDGLLSVADVIDREQLCPRS 94
Query: 640 -RPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIG 698
R + F+ V ++ ++ + + V D+ND + H+ + EN +G
Sbjct: 95 LRCLITFDIV-VRAKEKFQLI-HVEIEVKDINDHPP---RFPHNETHLEIVEN---VPLG 146
Query: 699 QIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYR 753
F ++ G ++ + I+ ++ EDG F + + LDRE D Y
Sbjct: 147 SRFPLEIALDQDVGENYIQSYNISPSSHFEVEVRDQEDGLKFAELVLVRELDREVEDSYT 206
Query: 754 MTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
+ V A + GV + +G V I + D NDN P FEH++ + E+S +G + +
Sbjct: 207 IKVTAT-DGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSPVGHRVLR---VH 262
Query: 814 ATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
A D DEG N Y L E +F VD TG V G +D E++ +Y+L + A D
Sbjct: 263 AFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKG-LVDFERRRLYELVIKASD 321
Query: 870 TGGLS--SEAELIIMIGDENDNKPEFN 894
G S S ++ I + D NDN PE +
Sbjct: 322 MGANSVPSTCKVHIDVVDVNDNAPEIS 348
Score = 70.9 bits (166), Expect = 2e-10
Identities = 50/172 (29%), Positives = 84/172 (48%), Gaps = 7/172 (4%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
FP I A+DQD+G Y + + ++ D +G F E L + + ++ +++
Sbjct: 149 FPLEI-ALDQDVGENYIQSYNISPSSHFEVEVRDQEDGLKFAELVLVRELDREVE-DSYT 206
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
++V A+ ++ V I++LD NDN P FE + + E+ P G VL+V A D
Sbjct: 207 IKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSPVGHRVLRVHAFDP 266
Query: 334 DQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
D+G NGE TY L + F +DP +G +T++ +R L +K
Sbjct: 267 DEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLYELVIK 318
Score = 64.1 bits (149), Expect = 3e-08
Identities = 122/507 (24%), Positives = 203/507 (40%), Gaps = 91/507 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS-KLSADALEVKRYFVINERH 998
I EN+P+G+ ALD D G N Y + + + D L+ ++ E
Sbjct: 139 IVENVPLGSRFPLEIALDQDVGENYIQSYNISPSSHFEVEVRDQEDGLKFAELVLVRELD 198
Query: 999 GHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-E 1055
V E + + ++A DGG + ++ V + V D ND+ P F+ + + E
Sbjct: 199 REV--------EDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDE 250
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPS---DTDLPFEISPLTGVLSVNGELDRET 1112
++ RVL +V A D D G N +TY + + F + P TG +++ G +D E
Sbjct: 251 DSPVGHRVL-RVHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFER 309
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
Y L + A D G DVNDN+P+ ++ P +D +
Sbjct: 310 RRLYELVIKASDMG-ANSVPSTCKVHIDVVDVNDNAPEI-----SIKPMTPGSDGV---- 359
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKN---QQNLG- 1228
A+I E A + VA + +D D NG + SL ++ QQ G
Sbjct: 360 -----------ASITEAAAADSFVALISTSDRD--SGSNGYVRVSLLGHEHFSLQQAYGD 406
Query: 1229 -LPSLSSTAILMVTVADVPDEV---EMSDKPVFISRYYELEI-EENVNAP--------VE 1275
+++TA+ + + V ++ + P R Y + + +EN N P V
Sbjct: 407 SFMIITTTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVS 466
Query: 1276 LVSLNLTEHY------------ENFKMRYYILN---ENDTDIRRTFVIDPRNGTLYLVRS 1320
++ N+ Y EN K+ Y +L+ + + +D +G+LY +RS
Sbjct: 467 VLENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRS 526
Query: 1321 PDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
D E +++++AE R P L + +KVV D NDN P F
Sbjct: 527 FDYETLQQIDLVIQAE----DRGSPS---------LSSTSTIRIKVV----DQNDNYPYF 569
Query: 1381 T---NGNRPLVTAIPTTAPFGYQVMQL 1404
T N +P AP GY +++
Sbjct: 570 TFPVLQNDSADVPLPFNAPAGYLALRV 596
Score = 58.4 bits (135), Expect = 1e-06
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 19/188 (10%)
Query: 220 AIDQDLGVGATLRYELIS-----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFV 273
A D D+G A + Y+++ G+ + S+DS +GSL+ + D + +
Sbjct: 482 ARDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRSFDYETLQQID----- 536
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSVLQV 328
L +QA +P ++ + + I+++D NDN P F + D ++ + N P G+ L+V
Sbjct: 537 LVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAPAGYLALRV 596
Query: 329 MATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
A D+D+G N ++Q+ F +D SG + ++ L E L +K+ +
Sbjct: 597 SAEDEDEGMNKVLSFQIFQGDTNLFRVDKDSGEIVLKQW--LSAEIGDVLEIKISVSDNG 654
Query: 388 PSVVGTFA 395
S + + A
Sbjct: 655 RSPLSSSA 662
Score = 57.2 bits (132), Expect = 3e-06
Identities = 58/187 (31%), Positives = 87/187 (46%), Gaps = 20/187 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE-KELDLDAEHNLQANTFVLQV 276
I D+D G +R L+ G++ FSL G F+ LD E + N L V
Sbjct: 375 ISTSDRDSGSNGYVRVSLL-GHEH--FSLQQAYGDSFMIITTTALDRERIPEYN---LTV 428
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A L NP + + + D NDN P F Y +S++EN G V V+A D D G
Sbjct: 429 VAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVG 488
Query: 337 ENGEFTYQLDD---PKGA-----FSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKET- 386
EN + +Y++ D P G+ S+D SG L T+R+ D E + + + A++
Sbjct: 489 ENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRS---FDYETLQQIDLVIQAEDRG 545
Query: 387 NPSVVGT 393
+PS+ T
Sbjct: 546 SPSLSST 552
Score = 51.6 bits (118), Expect = 2e-04
Identities = 94/369 (25%), Positives = 140/369 (37%), Gaps = 39/369 (10%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS- 1087
I V + VKD+NDH P F + + E A D D G+N +Y I PS
Sbjct: 114 IHVEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNISPSS 173
Query: 1088 --DTDLPFEISPLT-GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ ++ + L L + ELDRE ED Y + V A D G D
Sbjct: 174 HFEVEVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGG-VHARSGSMLVNIKVLDS 232
Query: 1145 NDNSPKF--YAFDELLEWKHPEADE-LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA 1201
NDNSP F + L+ P L H F+ + + T A V ++F
Sbjct: 233 NDNSPSFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVN-GEVTYALAAGFSPEVGRLFH 291
Query: 1202 NDTDFIGNGNGLILYSLPQRK------NQQNLGLPSLSSTAILMVTVADVPDEV-EMSDK 1254
D + G L +R+ ++G S+ ST + + V DV D E+S K
Sbjct: 292 VD-PYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIK 350
Query: 1255 PVFISRYYELEIEENVNAP--VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRN 1312
P+ I E A V L+S + + N +R +L +++ + +
Sbjct: 351 PMTPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSLLGHEHFSLQQAY---GDS 407
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
+ + DRE Y + V VAED+ K + VR+KD
Sbjct: 408 FMIITTTALDRERIPEYNLTV-----------------VAEDLGNPPFKTVRQYTVRVKD 450
Query: 1373 VNDNSPKFT 1381
NDN P F+
Sbjct: 451 ENDNPPLFS 459
Score = 51.6 bits (118), Expect = 2e-04
Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 17/182 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+HA D D GV + Y L +G +LF +D G + L+ +D + + + L
Sbjct: 261 VHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFE-----RRRLYEL 315
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN------ISIVENLPNGFSVLQV 328
++AS + + +V I+++D+NDN PE + SI E V +
Sbjct: 316 VIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVALI 375
Query: 329 MATDKDQGENGEFTYQLDDPKGAFSIDPRSG-WLTVRNQTVLDREAHSSLRMKVYAKET- 386
+D+D G NG L + FS+ G + T LDRE + V A++
Sbjct: 376 STSDRDSGSNGYVRVSLLGHE-HFSLQQAYGDSFMIITTTALDRERIPEYNLTVVAEDLG 434
Query: 387 NP 388
NP
Sbjct: 435 NP 436
Score = 50.0 bits (114), Expect = 5e-04
Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 14/161 (8%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQAN-TFVLQVQASQLNNPLKTAQ 289
+ L+ N+ + + V+G L + +D + +L+ TF + V+A + K
Sbjct: 59 FRLMQENNSSVIQMREVDGLLSVADVIDREQLCPRSLRCLITFDIVVRAKE-----KFQL 113
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
VEIE+ D+ND+ P F + ++ IVEN+P G +A D+D GEN +Y + P
Sbjct: 114 IHVEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNI-SPS 172
Query: 350 GAFSI---DPRSGWLTVRNQTV--LDREAHSSLRMKVYAKE 385
F + D G V LDRE S +KV A +
Sbjct: 173 SHFEVEVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATD 213
Score = 46.0 bits (104), Expect = 0.008
Identities = 51/197 (25%), Positives = 85/197 (43%), Gaps = 18/197 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ NIP G+ + + A D D G N ++ Y+ + +P V Y ++
Sbjct: 467 VLENNIP-GSYVTTVVARDPDVGENAKVSYKV-LDAEVPGGS------PVSTYVSVDSHS 518
Query: 999 GHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNFN 1053
G + RS E+ + L I A D G+ L+ ++R+ V D ND++P F N +
Sbjct: 519 GSLYTLRSFDYETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDS 578
Query: 1054 VEEAQYTRRVLG----KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ G +V A D D G N L++ I DT+L F + +G + + L
Sbjct: 579 ADVPLPFNAPAGYLALRVSAEDEDEGMNKVLSFQIFQGDTNL-FRVDKDSGEIVLKQWLS 637
Query: 1110 RETEDKYILTVVARDNG 1126
E D + + DNG
Sbjct: 638 AEIGDVLEIKISVSDNG 654
>UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 4354
Score = 108 bits (260), Expect = 1e-21
Identities = 117/462 (25%), Positives = 203/462 (43%), Gaps = 33/462 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V+VEV +LD NDN P+++ + +N++ G + +++A D D G +G+V Y L+
Sbjct: 1809 VDVEVVVLDVNDNRPIWMERERLA-RVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSP 1867
Query: 503 SN-------LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
SN PF INP T + VA S + + R+ L V A D R + +
Sbjct: 1868 SNDAKRKRRSPPQHPFTINPKTRQMEVAGS-LKDQRYDLDVFAFDY----GIPRLTSDTI 1922
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
T+ V G P P F Y F V + + VG I + + Y ++ G
Sbjct: 1923 TLNVDGSAAGQLP--PRFSKVSYHFMVSEDAKYLSLVGIILAR-SISGARLDYKIVSGNV 1979
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERG 674
A+ + ++ + D R ++ Y+ + A ++ + L + + V++ ND
Sbjct: 1980 GDKFIAMGDGRILLNSLLDFER-DQTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFP 2038
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG--NGTGNVRFLIANQQDVTDDIAI 732
+ +S I + + G + ++ + + G + + I ++ I
Sbjct: 2039 YFDQQLYSVQI--PESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYI 2096
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
G I LD E + + + V A +KG S G+ V + + + NDN P F +
Sbjct: 2097 DPATGKISVSVALDYEDQRYHLLKVYAT-DKGKKSFQGLCFVNVTLTNVNDNRPTFLKSA 2155
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
YE + E + G + I+ A DAD Y+ G G F VD++TGV+ +
Sbjct: 2156 YEFRVAEGAATGESLA---IVVAVDAD---GDAVTYSKAG-GALQFSVDQSTGVIT-LNS 2207
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+LD K Y L ++A+D+GGL+S + + D N+N P+F
Sbjct: 2208 ALDPNKN-QYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQF 2248
Score = 108 bits (259), Expect = 1e-21
Identities = 128/484 (26%), Positives = 210/484 (43%), Gaps = 44/484 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+ V + DAND PVF S+ Y ++ N + T + +V+A D D G NG + Y ++
Sbjct: 235 NIRVNVEDANDQTPVF-ESSQYRETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPV 293
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
N S F I+ TG + VA++ R H L++ A D+ P R + A V I +
Sbjct: 294 N----SYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPP--RTSAEATVEISLRE 347
Query: 562 GTKG-NKPDIPD--------FMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDL 610
+G PD D F + Y F + + ++ +R ND N
Sbjct: 348 NIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADNDPIGPNKRLRYS 407
Query: 611 LHGYEEGVP-FAVEERSGVITVVDDLSRYNRP---MYDFEAVALQEN-ANLSIVTNATVH 665
L G GV FA++ SGV+T+ D + N P +YD A + +LS T +
Sbjct: 408 LSG--NGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQGPGSLSATTQLLIE 465
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGT---GNVRFLIA 721
+ DV DE + I + EN + + + T+ S+ GN + G V + I
Sbjct: 466 IQDV-DENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSV-GNPSSPDGKVVYSIV 523
Query: 722 NQQDVTDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ + G + P LDRE Y + V A N + ++ + I + DE
Sbjct: 524 GGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSSRLF-LMINLLDE 582
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
+DN P F Y + EN GT + ++ DADEG N YT+ G + ++
Sbjct: 583 DDNFPYFSQPIYIAQVPENQPSGTFV---TVVVGRDADEGFNP--SYTVITPGVP-YKIE 636
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVAR--DTGGLSSEAELIIMIGDENDNKPEFNQIEE 898
+TGV++ SLD+ + +L ++ R G +++ ++ I + + + P F
Sbjct: 637 PSTGVIR-TSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTPY 695
Query: 899 NSKV 902
+ KV
Sbjct: 696 SVKV 699
Score = 107 bits (258), Expect = 2e-21
Identities = 217/915 (23%), Positives = 359/915 (39%), Gaps = 116/915 (12%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+L+ + + + + D NDN P F+ + Y S+ S+A G+ I V+A D D G N +
Sbjct: 2335 ERLLWYCYLTINVEDVNDNRPYFLAAK-YFGSVFSSAPNGSNILTVQATDADSGSNAKIK 2393
Query: 497 YDLQRTSN--LTITSPFKINPNTGTVSVAESPILEGRHALF-VEASDQPANPSERRYSLA 553
Y L ++ + S + NT A + G+ L V A D + +
Sbjct: 2394 YALLDSAGGLFRLDSSGILRTNTNP---ARLQLETGKKLLLEVSAKDVESIAGTQPGKPT 2450
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
T ++ +P P F Y + N+ G++V +I + ++SY+ +
Sbjct: 2451 KYTTQIEILVSNEEP--PKFSQQVYTASINENMETGSTVTRITATSSTGA-EISYENVDT 2507
Query: 614 YEEG-VPFAVEERSGVITVVDDLSRYNR-PMYDFEAVALQENANLSIVTNATVHVVDVND 671
+ F V+ +IT D Y R Y+ + A + L ++++DVND
Sbjct: 2508 NPRAKILFRVQPDGYIIT--GDRPDYERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVND 2565
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
L ++ ++ A + +M +I +G+ R + +D +
Sbjct: 2566 VSPAFLLAINTRNARVLENKPAPTKV-----ISMKAIDDDGSEPHRRVTYEMKDNPNFQI 2620
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
A G I T+ LDRE Y + V A+ GV + I +T+ D+ND PPVF +
Sbjct: 2621 DASTGMITTKTTLDREVTPKYDVEVTAK--DGVNKESAILYITVV--DQNDQPPVFAPKS 2676
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + E D+ GT+ L +Y DV EN + FI
Sbjct: 2677 YAISVPE-----------------DSPIGTSVLDIYATDA------DVGENAKITYFISK 2713
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
D E K S+V G EL++ + K +F + + K +
Sbjct: 2714 G-DPEGKF----SIVTSPVKG-----ELVV------NGKLDFETKSSYTLEVTATDGKFS 2757
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSG-LN 963
TA T+ DV+ L P+F P EN G ++ + A D+DS ++
Sbjct: 2758 DTAVVTVT--------IQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDIDSPTIS 2809
Query: 964 GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG 1023
+ I P + S +V + R G + R P F + A DG
Sbjct: 2810 FSLDDRGKDYFQITPIRASGPG----NVWVGDIRTGSKQLDREESPVKVF--TVIANDGK 2863
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANL 1080
+ +RV + DVND+ P F + Y VEE + + + + A D D G NA L
Sbjct: 2864 H-TAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKL 2922
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRE-TEDKYILTVVARDNGXXXXXXXXXXXXX 1139
+Y + S D F I PL+G++ DRE T +K+ + V A D G
Sbjct: 2923 SYELTDSAGD-KFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAG-NPRLSASVDGII 2980
Query: 1140 XXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
D ND+ PKF ++ E + + SV+ + + NA V +
Sbjct: 2981 HVSDANDHKPKFTE-----KFYRGSVAENAPPGY-SVLRVTATDEDVGPNAEFEFVVVQG 3034
Query: 1200 FANDTDFIGNGNGLILYS--LPQRKNQQ--------NLGLPSL--SSTAILMVTVADVPD 1247
+I NG +L S L K ++ + G+P L TA +++ + D D
Sbjct: 3035 NDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDAND 3094
Query: 1248 EVEMSDKPVFISRYYELEIEENVNA--PVELVSLNLTEHYENFKMRYYILNENDTDIRRT 1305
+ P FI + Y + E+V A PV V+ + N + I +D D T
Sbjct: 3095 -----NAPEFIPKIYNASVLEDVGARQPVLTVTAVDKDSGPNGNFTFAIDPRSDPDDAFT 3149
Query: 1306 FVIDPRNGTLYLVRS 1320
+P N ++ ++R+
Sbjct: 3150 IEPNPNNASIGIIRT 3164
Score = 106 bits (255), Expect = 4e-21
Identities = 124/501 (24%), Positives = 226/501 (45%), Gaps = 46/501 (9%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
K + E + L S V+V++ +++AND+ P F LY + + VG ++ +V A D
Sbjct: 2009 KVKATEQIPDGLDSTVDVKIDVINANDHFPYF-DQQLYSVQIPESTAVGVLVQEVTAKDC 2067
Query: 488 DLGQN-----GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD 540
D + G + Y ++ + F I+P TG +SV+ + E + H L V A+D
Sbjct: 2068 DCLSSCTCSPGFLTYSIEPSKEQ--GGKFYIDPATGKISVSVALDYEDQRYHLLKVYATD 2125
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
+ + L V + +T N+ P F+ + YEF V G S+ + DA
Sbjct: 2126 KGKKSFQ---GLCFVNVTLT-NVNDNR---PTFLKSAYEFRVAEGAATGESLAIVVAVDA 2178
Query: 601 FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT 660
+ + V+Y G + F+V++ +GVIT+ L N+ Y + +A +++ L+
Sbjct: 2179 -DGDAVTYSKAGG---ALQFSVDQSTGVITLNSALDP-NKNQYTLQVMA-KDSGGLTSTV 2232
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ T +V D N+ + + + + + + I Q+ T+ G + + I
Sbjct: 2233 SVTFNVADANNN---VPQFTNCGTVSIRENDPRDTKITQLTATDADR---GQNGQITYSI 2286
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGAGIY--QVTIY 776
+ T G + + LDRE +D Y + AE +K S ++ +TI
Sbjct: 2287 EDASSQTLFSIEPRTGVVRSLTSLDRENKDSYNAIIKAEDGSSKQDESERLLWYCYLTIN 2346
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ED NDN P F A Y G + ++ G+ I ++ATDAD G+NA Y L +
Sbjct: 2347 VEDVNDNRPYFLAAKYFGSVFSSAPNGSNIL---TVQATDADSGSNAKIKYALLDSAGGL 2403
Query: 837 FDVDENTGVVKFIGD----SLDREKKIMYKLSL-----VARDTGGLSSEAELIIMIGDEN 887
F +D ++G+++ + L+ KK++ ++S +A G ++ I I N
Sbjct: 2404 FRLD-SSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQPGKPTKYTTQIEILVSN 2462
Query: 888 DNKPEFNQIEENSKVRIHRET 908
+ P+F+Q + + + ET
Sbjct: 2463 EEPPKFSQQVYTASINENMET 2483
Score = 105 bits (251), Expect = 1e-20
Identities = 101/332 (30%), Positives = 153/332 (46%), Gaps = 36/332 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA-FIFLIAPIGP------SLTI 130
+A + V + DVNDN P F +PY V+E P+G +I + P L+
Sbjct: 2865 TAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSY 2924
Query: 131 PLTVPRG--------LTIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPV 181
LT G + K FDR++ TPN + + V D G+ L +S +
Sbjct: 2925 ELTDSAGDKFSIDPLSGLIKTKVTFDREQ--TPNK---FKVRVKATDAGNPRLSASVDGI 2979
Query: 182 LLLRKVLDYDAGDKE-FQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ + D+ E F +A +L + A D+D+G A + ++ GND
Sbjct: 2980 IHVSDANDHKPKFTEKFYRGSVAENAPPGYSVL---RVTATDEDVGPNAEFEFVVVQGND 3036
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ-ARVEIELLDL 299
F +D NG++ + LD + + T L V A + PL+ + A V IE+LD
Sbjct: 3037 PHAFYIDPFNGTVLVSGILDYEKKKEY---TITLTV-ADRGMPPLQGDETAYVVIEILDA 3092
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKGAFSIDP 356
NDN PEF YN S++E++ VL V A DKD G NG FT+ +D DP AF+I+P
Sbjct: 3093 NDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDKDSGPNGNFTFAIDPRSDPDDAFTIEP 3152
Query: 357 RSGWLT---VRNQTVLDREAHSSLRMKVYAKE 385
+ +R + LD+E S +KV A +
Sbjct: 3153 NPNNASIGIIRTRVPLDQEKTPSFHLKVTATD 3184
Score = 91.9 bits (218), Expect = 1e-16
Identities = 122/465 (26%), Positives = 185/465 (39%), Gaps = 34/465 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VT+ D ND PVF S LYE ++ N G + V A D D L D R +
Sbjct: 2762 VTVTIQDVNDLPPVF-SSPLYESRIQENTGPGAGVVMVTASDIDSPTISFSLDD--RGKD 2818
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+P + + G V V + I G L E S E+
Sbjct: 2819 YFQITPIRAS-GPGNVWVGD--IRTGSKQLDREESPVKVFTVIANDGKHTAQAEIRVNLT 2875
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND-----AFEQNDVSYDLLHGYEEGVP 619
+ P F +PY +V N GTSV I+ D A +SY+L G
Sbjct: 2876 DVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTDS--AGDK 2933
Query: 620 FAVEERSGVITVVDDLSRYNRP-MYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLL 677
F+++ SG+I R P + A N LS + +HV D ND +
Sbjct: 2934 FSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSDANDHKPKFT 2993
Query: 678 KGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ + V EN+ G ++ ++ T+ + N F++ D +G
Sbjct: 2994 EKFYRG---SVAENAPPGYSVLRVTATD-EDVGPNA--EFEFVVVQGNDPHAFYIDPFNG 3047
Query: 737 TIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
T+ LD EK+ Y +T+ +A+ + G V I I D NDN P F Y
Sbjct: 3048 TVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKIYNAS 3107
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF--GEGKEMFDVDENT-----GVVKF 848
++E+ +G + + A D D G N F + + + + F ++ N G+++
Sbjct: 3108 VLED--VGARQPVLTVT-AVDKDSGPNGNFTFAIDPRSDPDDAFTIEPNPNNASIGIIR- 3163
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
LD+EK + L + A D GGL E E+ I + D NDN P F
Sbjct: 3164 TRVPLDQEKTPSFHLKVTATDAGGLQGEGEVRINVIDVNDNGPWF 3208
Score = 91.1 bits (216), Expect = 2e-16
Identities = 123/470 (26%), Positives = 200/470 (42%), Gaps = 80/470 (17%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ PIGT+++ + A D D G N +I Y F S+ P K S VK V+N +
Sbjct: 2681 VPEDSPIGTSVLDIYATDADVGENAKITY-FISK-GDPEGKFSIVTSPVKGELVVNGK-- 2736
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+S + L ++A D G +D V V ++DVND PVF Y ++E
Sbjct: 2737 -----LDFETKSSYTLEVTATD-GKFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTG 2790
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG----------VLSVNGELD 1109
+ V A+D D + +++ + D F+I+P+ + + + +LD
Sbjct: 2791 PGAGVVMVTASDID---SPTISFSLDDRGKDY-FQITPIRASGPGNVWVGDIRTGSKQLD 2846
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
RE + TV+A D DVNDN+P+F A + + E ++ S
Sbjct: 2847 REESPVKVFTVIANDG----KHTAQAEIRVNLTDVNDNAPRFPASPYI---GYVEENKPS 2899
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG------NGLI----LYSLP 1219
SVM Y ++++ P+ AK+ TD G+ +GLI +
Sbjct: 2900 G---TSVM----YIQAVDDDDPLAGGNAKLSYELTDSAGDKFSIDPLSGLIKTKVTFDRE 2952
Query: 1220 QRKNQ-------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
Q N+ + G P LS++ ++ V+D D KP F ++Y + EN
Sbjct: 2953 QTPNKFKVRVKATDAGNPRLSASVDGIIHVSDANDH-----KPKFTEKFYRGSVAENAPP 3007
Query: 1273 PVELVSLNLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYE 1330
++ + T+ N + + ++ ND F IDP NGT+ + D E K Y
Sbjct: 3008 GYSVLRVTATDEDVGPNAEFEFVVVQGNDP---HAFYIDPFNGTVLVSGILDYEKKKEYT 3064
Query: 1331 VIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ + R +P P+ D T Y VV+ I D NDN+P+F
Sbjct: 3065 ITLTVA----DRGMP----PLQGD----ETAY---VVIEILDANDNAPEF 3099
Score = 89.4 bits (212), Expect = 7e-16
Identities = 115/444 (25%), Positives = 182/444 (40%), Gaps = 39/444 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+L S V +VT++D NDN P F + + S + T + +A+D D G G V
Sbjct: 1090 ELASEVVAKVTIVDVNDNGPRFAFHESSKTVVIDSFSAKDTQL--ARALDADSGSLGEVT 1147
Query: 497 YDL---QRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSL 552
Y + + TSNL PF IN TG + + E +G + + + A ++
Sbjct: 1148 YGIDGGRSTSNL----PFNINVKTGMIFATREILYTQGSSYIIIVVATDGATDGSQKIQK 1203
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V ++V + P P F Y V G+G +V +R + + Y +
Sbjct: 1204 FTVNVQVL-----DTPRPPSFPQKTYSAPVTETAGVGDTVTTVRAVYSKPNAFLKYTFVS 1258
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDF-EAVALQENANLSIVTNATVHVVDVND 671
G E+ F V G+I+V L R Y V L ++ + T V++ D+ND
Sbjct: 1259 GNEDNT-FCV-NGFGIISVAKSLDREKVAGYTLGMRVTLGQHVD---DTTVYVNLTDIND 1313
Query: 672 E-----RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
+ + + + + A+ F +N +Y +G + D
Sbjct: 1314 DAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSILSG-----VHPDWDK 1368
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+I A G I T+ LD E + + + AE N +GI QV I + D NDN PV
Sbjct: 1369 YFNIDSA-TGKITTKMTLDYETHKSHTLFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPV 1427
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
F A Y I + GT + + ATD D G N Y++ G +E F ++E GV
Sbjct: 1428 FAAAFYRAKISLGAVKGTSVLQ---VHATDLDSGQNGQITYSIIQGNEEEAFTINEQ-GV 1483
Query: 846 VKFIGDSLDREKKIMYKLSLVARD 869
+ + SL + L + ARD
Sbjct: 1484 I-LVDKSLTTVAADKFSLKVEARD 1506
Score = 88.2 bits (209), Expect = 2e-15
Identities = 167/696 (23%), Positives = 275/696 (39%), Gaps = 77/696 (11%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN-GS-LFLEKELDLDAEHNL----QA 269
E HA D+D Y +ISGN++ F +++V GS + K L L
Sbjct: 155 EQCHATDRD--TSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDN 212
Query: 270 NTFV-LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
N ++ L VQ + NP + A + + + D ND P FE Y +I EN P SVL+V
Sbjct: 213 NPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRV 272
Query: 329 MATDKDQGENGEFTYQLDDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-- 385
ATDKD G NG Y + +P + F+ID +G +R LD A + + A++
Sbjct: 273 RATDKDDGTNGGIYYYMKNPVNSYFTIDAITG--VIRVAKTLDYNARDKHTLYISARDRG 330
Query: 386 ----TNPSVVGTFADSQRIAKWRRQPLETNA-PLEKTTYVFPDKVGTKTENIEYYDEQLM 440
T+ + + I W PL +A P E T FP T + ++ + +
Sbjct: 331 DPPRTSAEATVEISLRENIQGW---PLPDSADPKENTKPYFPQSRYTFSIREDFPPKGAL 387
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++ A DN+P+ P+ +S+ N + K A+DP+ G + L D
Sbjct: 388 -------LVMRAADNDPI-GPNKRLRYSLSGNG-----VSKF-AIDPESGV--VTLTDSV 431
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
N + + T T + L L +E D N + R+ +E++
Sbjct: 432 DYENTPNNHVYDL---TVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEIS 488
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
K N + + A VG N + V Y ++ G GV F
Sbjct: 489 ENLKQN--SLVTTVSATDSDSVG--------------NPSSPDGKVVYSIVGGTGLGV-F 531
Query: 621 AVEERSGVITV-VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
V+ +G + V V L R Y V +NA + + ++++ DE
Sbjct: 532 RVDSNTGEVKVAVPSLDREGTSQYTL-VVKASDNATFPRSSRLFL-MINLLDEDDNFPYF 589
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+ I V EN F T + + N + + V I G I
Sbjct: 590 SQPIYIAQVPENQPSGT----FVTVVVGRDADEGFNPSYTVIT-PGVPYKIE-PSTGVIR 643
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T K LD+ + + VI + S QV I + + + PPVF++ Y + E
Sbjct: 644 TSKSLDQSELSTRELQVIVRVSTAG-SKTADGQVNITVISKVNRPPVFKNTPYSVKVPE- 701
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
++G + N+ D + + YTL +F+VD+++G + +S + E
Sbjct: 702 -EMG---PLPNLFCIAAVDSLSRPV-QYTLAPGADGLFEVDKDSGRL-HTKNSFNYENVD 755
Query: 860 MYKLSLVARDTGGLS-SEAELIIMIGDENDNKPEFN 894
Y L + AR + + A L + + +E D P+F+
Sbjct: 756 RYNLRIEARTSSVQEVASASLTVEVTEEKD-LPKFS 790
Score = 87.4 bits (207), Expect = 3e-15
Identities = 106/469 (22%), Positives = 191/469 (40%), Gaps = 45/469 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
+ + VEV ++D ND+ P F+ + Y S+ S+ G+ + V+A D D+G N V Y+
Sbjct: 881 MFATAQVEVNVIDVNDHKPEFLQES-YWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYE 939
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L R N + F +N N +S A + R+ L + ASD + R S A V +
Sbjct: 940 LLRQEN---SERFILNDN-NQLSTASTLTPNVRYQLLIRASDS----ATRNPSSAQVPVY 991
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE-- 616
V+ + P + F + Y + + T V + + + ++Y+L+ GY++
Sbjct: 992 VSVYSPSESPIV--FDKSSYNQNLPEDSSANTLVFTAKATRSGSSSGITYELVGGYKQIG 1049
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN--ATVHVVDVNDE-- 672
F+++ +G + ++ L + + A + + + A V +VDVND
Sbjct: 1050 EAMFSIKPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGP 1109
Query: 673 RGVLLKGAHSPII--FHVKENSAGAAI----GQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
R + + + +I F K+ A+ G + G T N+ F I
Sbjct: 1110 RFAFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRSTSNLPFNIN----- 1164
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA-GIYQVTIYIED-ENDNP 784
+ G IF + + + Y + V+A G G+ I + T+ ++ + P
Sbjct: 1165 ------VKTGMIFATREILYTQGSSYIIIVVA--TDGATDGSQKIQKFTVNVQVLDTPRP 1216
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG 844
P F TY + E + +G D + NA YT ++ G
Sbjct: 1217 PSFPQKTYSAPVTETAGVG-----DTVTTVRAVYSKPNAFLKYTFVSGNEDNTFCVNGFG 1271
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
++ + SLDREK Y L + G + + + + D ND+ P F
Sbjct: 1272 IIS-VAKSLDREKVAGYTLGMRV-TLGQHVDDTTVYVNLTDINDDAPHF 1318
Score = 85.0 bits (201), Expect = 1e-14
Identities = 109/444 (24%), Positives = 185/444 (41%), Gaps = 52/444 (11%)
Query: 1010 ESEFRLNISALDG--GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
++++ L + A + L+ + V++ V + NDHFP F + Y+ + E+ ++ +V
Sbjct: 2003 QTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFPYFDQQLYSVQIPESTAVGVLVQEV 2062
Query: 1068 DATDADFGQNAN-----LTYFIQPS-DTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
A D D + LTY I+PS + F I P TG +SV+ LD E + ++L V
Sbjct: 2063 TAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVY 2122
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPV 1181
A D G +VNDN P F E++ E ES+ ++
Sbjct: 2123 ATDKG-KKSFQGLCFVNVTLTNVNDNRPTF--LKSAYEFRVAEGAATG----ESLAIVVA 2175
Query: 1182 YKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY--SLPQRKNQQNLGLPS-----LSS 1234
A + T +K + G+I +L KNQ L + + L+S
Sbjct: 2176 VDADGD-----AVTYSKAGGALQFSVDQSTGVITLNSALDPNKNQYTLQVMAKDSGGLTS 2230
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRY 1292
T + VAD + V P F + + I EN ++ L T + +N ++ Y
Sbjct: 2231 TVSVTFNVADANNNV-----PQF-TNCGTVSIRENDPRDTKITQLTATDADRGQNGQITY 2284
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
I D + F I+PR G + + S DRE KD+Y I++AE
Sbjct: 2285 SI---EDASSQTLFSIEPRTGVVRSLTSLDRENKDSYNAIIKAEDGSSK----------- 2330
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHP 1412
+D E + Y + + ++DVNDN P F ++ ++AP G ++ ++
Sbjct: 2331 QDESERLLWY-CYLTINVEDVNDNRPYFLAAK--YFGSVFSSAPNGSNILTVQATDADSG 2387
Query: 1413 TASRTVRADTDELVFFERLSLNGL 1436
+ ++ A D RL +G+
Sbjct: 2388 SNAKIKYALLDSAGGLFRLDSSGI 2411
Score = 83.8 bits (198), Expect = 3e-14
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 14/179 (7%)
Query: 217 PIHAIDQDLGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
P+ A+D D G + Y ++SG + K F++DS G + + LD + +
Sbjct: 1340 PVIAVDHDFGSNGKILYSILSGVHPDWDKYFNIDSATGKITTKMTLDYETH-----KSHT 1394
Query: 274 LQVQASQLNNPLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L ++A +P + + A+V+I+++D NDN P F FY I G SVLQV ATD
Sbjct: 1395 LFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHATD 1454
Query: 333 KDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D G+NG+ TY + + + AF+I+ + L ++ T + A +KV A++ N S
Sbjct: 1455 LDSGQNGQITYSIIQGNEEEAFTINEQGVILVDKSLTTV---AADKFSLKVEARDKNAS 1510
Score = 80.6 bits (190), Expect = 3e-13
Identities = 101/400 (25%), Positives = 164/400 (41%), Gaps = 34/400 (8%)
Query: 992 FVINERHGHVIVARSLPP-ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWY 1050
F +++ G + + +L P ++++ L + A D G L +SV V D N++ P F
Sbjct: 2194 FSVDQSTGVITLNSALDPNKNQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCG- 2252
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
++ E + ++ ATDAD GQN +TY I+ + + F I P TGV+ LDR
Sbjct: 2253 TVSIRENDPRDTKITQLTATDADRGQNGQITYSIEDASSQTLFSIEPRTGVVRSLTSLDR 2312
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXX----XXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
E +D Y + A D DVNDN P F A K+ +
Sbjct: 2313 ENKDSYNAIIKAEDGSSKQDESERLLWYCYLTINVEDVNDNRPYFLAA------KYFGSV 2366
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQN 1226
S N +++ + A NA I A + + F + +G+ L N
Sbjct: 2367 FSSAPNGSNILTVQATDADSGSNAKI--KYALLDSAGGLFRLDSSGI----LRTNTNPAR 2420
Query: 1227 LGLPSLSSTAILMVTVADVPDEV-EMSDKPVFISRYYELEI--EENVNAPVELVSLNLTE 1283
L L + +L V+ DV KP + E+ + EE ++ + ++ E
Sbjct: 2421 LQLET-GKKLLLEVSAKDVESIAGTQPGKPTKYTTQIEILVSNEEPPKFSQQVYTASINE 2479
Query: 1284 HYENFKMRYYILNENDTDIRRTFV---IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKY 1340
+ E I + T ++ +PR L+ V+ PD I+ +R Y
Sbjct: 2480 NMETGSTVTRITATSSTGAEISYENVDTNPRAKILFRVQ-PD-------GYIITGDRPDY 2531
Query: 1341 SRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
R + + A+D + + VKVV+ I DVND SP F
Sbjct: 2532 ERGTTYNMQFAAKD-KKTLLYSTVKVVINIIDVNDVSPAF 2570
Score = 77.8 bits (183), Expect = 2e-12
Identities = 109/431 (25%), Positives = 176/431 (40%), Gaps = 63/431 (14%)
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T KP+ R+ + Y M + + G S +G + + +ED ND PVFE + Y I EN
Sbjct: 203 TGKPIVRDDNNPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAEN 262
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ I T + ++ATD D+GTN Y + F +D TGV++ + +LD +
Sbjct: 263 TPIQTSVLR---VRATDKDDGTNGGIYYYMKNPVNSYFTIDAITGVIR-VAKTLDYNARD 318
Query: 860 MYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
+ L + ARD G S+EA + I + + P + +++ + K N F
Sbjct: 319 KHTLYISARDRGDPPRTSAEATVEISLRENIQGWP----LPDSA------DPKENTKPYF 368
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS-GLNGQIRYEFNSEVY 975
P++++ F I E+ P ++ + A D D G N ++RY
Sbjct: 369 ------PQSRYT---------FSIREDFPPKGALLVMRAADNDPIGPNKRLRY------- 406
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSL-----PPESEFRLNISALD--GGNLNDN 1028
LS + + F I+ G V + S+ P + L ++A D G+L+
Sbjct: 407 ----SLSGNGVS---KFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQGPGSLSAT 459
Query: 1029 ISVRVFVKDV--NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN-----ANLT 1081
+ + ++DV N + P F + E ++ V ATD+D N +
Sbjct: 460 TQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPSSPDGKVV 519
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVN-GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y I F + TG + V LDRE +Y L V A DN
Sbjct: 520 YSIVGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDN-ATFPRSSRLFLMIN 578
Query: 1141 XXDVNDNSPKF 1151
D +DN P F
Sbjct: 579 LLDEDDNFPYF 589
Score = 77.8 bits (183), Expect = 2e-12
Identities = 80/314 (25%), Positives = 124/314 (39%), Gaps = 9/314 (2%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLIAPIGPSLTIPLTVPR-GLTI 140
V V + +VNDN P FL + Y V E TGE A + + G ++T ++
Sbjct: 2137 VNVTLTNVNDNRPTFLKSAYEFRVAEGAATGESLAIVVAVDADGDAVTYSKAGGALQFSV 2196
Query: 141 FKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLV 200
+ + PN + + V D G L S+ V + V D + +F
Sbjct: 2197 DQSTGVITLNSALDPNKNQYTLQVMAKDSG--GLTST---VSVTFNVADANNNVPQFTNC 2251
Query: 201 IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD 260
S + + A D D G + Y + + + LFS++ G + LD
Sbjct: 2252 GTVSIRENDPRDTKITQLTATDADRGQNGQITYSIEDASSQTLFSIEPRTGVVRSLTSLD 2311
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
+ + + A + Q + + I + D+NDN P F Y S+ + P
Sbjct: 2312 RENKDSYNAIIKAEDGSSKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAP 2371
Query: 321 NGFSVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
NG ++L V ATD D G N + Y LD G F +D T N L E L +
Sbjct: 2372 NGSNILTVQATDADSGSNAKIKYALLDSAGGLFRLDSSGILRTNTNPARLQLETGKKLLL 2431
Query: 380 KVYAKETNPSVVGT 393
+V AK+ S+ GT
Sbjct: 2432 EVSAKDVE-SIAGT 2444
Score = 73.7 bits (173), Expect = 3e-11
Identities = 53/176 (30%), Positives = 83/176 (47%), Gaps = 6/176 (3%)
Query: 954 NALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
+A D D SG+ G N + Y + + R F++ + G IV P
Sbjct: 158 HATDRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPY-- 215
Query: 1013 FRLNISALDGGNLNDN--ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
L + DGGN + + ++RV V+D ND PVF+ + Y + E + + +V AT
Sbjct: 216 IMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRAT 275
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D D G N + Y+++ + + F I +TGV+ V LD DK+ L + ARD G
Sbjct: 276 DKDDGTNGGIYYYMK-NPVNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRG 330
Score = 73.3 bits (172), Expect = 5e-11
Identities = 82/302 (27%), Positives = 128/302 (42%), Gaps = 40/302 (13%)
Query: 120 LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH- 178
+ AP ++++P P G ++ DI A D D N+ + Y I G+ +G F++ +S
Sbjct: 2671 VFAPKSYAISVPEDSPIGTSVL-DIYATDADVGE--NAKITYFISKGDPEGKFSIVTSPV 2727
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL-------------FPEPIHA--IDQ 223
K L++ LD++ V GK ++ F P++ I +
Sbjct: 2728 KGELVVNGKLDFETKSSYTLEVTATDGKFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQE 2787
Query: 224 DLGVGATLRYELISGNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVL-QVQASQ 280
+ G GA + S D FSLD F + N+ Q +
Sbjct: 2788 NTGPGAGVVMVTASDIDSPTISFSLDDRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDR 2847
Query: 281 LNNPLK-----------TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+P+K TAQA + + L D+NDN P F Y + EN P+G SV+ +
Sbjct: 2848 EESPVKVFTVIANDGKHTAQAEIRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQ 2907
Query: 330 ATDKDQ---GENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A D D G N + +Y+L D G FSIDP SG ++ + DRE + + KV K
Sbjct: 2908 AVDDDDPLAGGNAKLSYELTDSAGDKFSIDPLSG--LIKTKVTFDRE-QTPNKFKVRVKA 2964
Query: 386 TN 387
T+
Sbjct: 2965 TD 2966
Score = 72.9 bits (171), Expect = 6e-11
Identities = 113/474 (23%), Positives = 195/474 (41%), Gaps = 44/474 (9%)
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT-VIGK 481
+KV T + Q + V V L D ND+ P F S +Y S+K T ++
Sbjct: 1282 EKVAGYTLGMRVTLGQHVDDTTVYVNLTDINDDAPHFT-SAIYRRSIKEGLAEDTEILPP 1340
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEAS 539
V AVD D G NG +LY + + F I+ TG ++ + E H LF+ A
Sbjct: 1341 VIAVDHDFGSNGKILYSILSGVHPDWDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAE 1400
Query: 540 DQPANPSERRYS-LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN 598
D N S +R S +A V I+V + P F A Y + GTSV Q+
Sbjct: 1401 D---NGSPKRLSGIAQVDIDVI----DRNDNSPVFAAAFYRAKISLGAVKGTSVLQVHAT 1453
Query: 599 --DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL 656
D+ + ++Y ++ G EE F + E+ GVI V L+ + + A +NA+
Sbjct: 1454 DLDSGQNGQITYSIIQGNEEEA-FTINEQ-GVILVDKSLTTVAADKFSLKVEARDKNASP 1511
Query: 657 ---SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
S+ V++ D V SP+ +VKE G + ++ + +
Sbjct: 1512 RSGSVTVEINVYLPDGPPMFVV------SPVTVYVKE-------GVPANHRVAGVKAATS 1558
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ + + + + G++ + LD E+R Y + + A + + + ++
Sbjct: 1559 EALTYTLLSGNEAGMFRINPSTGSLDATRELDYEERRRYELKIEARDTR---DRSAMVEL 1615
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIG----TEIKMDNIIKATDADEGTNALFMYTL 829
I + + NDN P F +G I + IG T+I +I A + + +
Sbjct: 1616 IIIVVNINDNKPTFVDIV-DGQI-DRKAIGTCSPTDIAEGEVITRLGAFDRDGDEITFIV 1673
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ K++F +D + GVV D K +Y ++ A D G E ++ + +
Sbjct: 1674 PDDVKDLFKID-SRGVVTAKKPIEDLPK--IYPFNVKALDNGEPPQETDVKVRL 1724
Score = 71.3 bits (167), Expect = 2e-10
Identities = 60/223 (26%), Positives = 101/223 (45%), Gaps = 23/223 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+P + P G++++ + A D+D G N Q+RYE + E F++N+ +
Sbjct: 910 VPSSTPAGSSLVTVQAEDMDIGTNAQVRYELLRQ-------------ENSERFILNDNN- 955
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDN---ISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ A +L P ++L I A D N + + V V V ++ VF K+ YN N+ E
Sbjct: 956 QLSTASTLTPNVRYQLLIRASDSATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPE 1015
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP---FEISPLTGVLSVNGELDRETE 1113
++ AT + G ++ +TY + + F I P TG + + +LD ET+
Sbjct: 1016 DSSANTLVFTAKATRS--GSSSGITYELVGGYKQIGEAMFSIKPDTGQVYLIKKLDFETK 1073
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDE 1156
+ + V A+ +G DVNDN P+F AF E
Sbjct: 1074 SYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRF-AFHE 1115
Score = 69.3 bits (162), Expect = 8e-10
Identities = 83/338 (24%), Positives = 140/338 (41%), Gaps = 29/338 (8%)
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSV--GQIRVNDAFEQND-VSYDLLHGYEEGVP--FAVE 623
D P F A Y + + T + I V+ F N + Y +L G F ++
Sbjct: 1314 DAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSILSGVHPDWDKYFNID 1373
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDVNDERGVLLKGA 680
+G IT L + + ++N + LS + + V+D ND V
Sbjct: 1374 SATGKITTKMTLDYETHKSHTL-FIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAA- 1431
Query: 681 HSPIIFHVKENSAGAAIG-QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
F+ + S GA G + + + + G + + I Q + + I E G I
Sbjct: 1432 -----FYRAKISLGAVKGTSVLQVHATDLDSGQNGQITYSII-QGNEEEAFTINEQGVIL 1485
Query: 740 TQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
K L D + + V A + N SG+ ++ +Y+ D PP+F + ++ E
Sbjct: 1486 VDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVYLPD---GPPMFVVSPVTVYVKE 1542
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKK 858
+ ++ + AT + AL L G MF ++ +TG + + LD E++
Sbjct: 1543 G--VPANHRVAGVKAAT-----SEALTYTLLSGNEAGMFRINPSTGSLDATRE-LDYEER 1594
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
Y+L + ARDT S+ ELII++ + NDNKP F I
Sbjct: 1595 RRYELKIEARDTRDRSAMVELIIIVVNINDNKPTFVDI 1632
Score = 68.9 bits (161), Expect = 1e-09
Identities = 116/468 (24%), Positives = 187/468 (39%), Gaps = 46/468 (9%)
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDRE--KRDVYRMTVIAEFNKGVI 765
++ + +G+V L V I+E G + + + ++ E K + Y +TV+ +
Sbjct: 49 LFDSSSGDVFSLYQADPTVPLLFQISEVGHVTSTQEIEYEIGKTNKYDLTVLQRPRGETL 108
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHAT---YEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G I + I I D N+ PVF+ + YEGF+ E + T ++ ATD D T+
Sbjct: 109 GGIAI-TLRITILDVNNFHPVFQLSQGEHYEGFVKEGTAENTIVEGLEQCHATDRD--TS 165
Query: 823 ALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
+ Y++ G K F V+ V+ IG + K LV + TG + I+
Sbjct: 166 GIRGYSIISGNEKGYFKVE----TVQ-IGSGVTSRK------FLVLKTTG------KPIV 208
Query: 882 MIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
+DN P I +V +GTA + V+ N + I
Sbjct: 209 ----RDDNNP---YIMLTVQVTDGGNPSHSGTANIRV-NVEDANDQTPVFESSQYRETIA 260
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV--YIPPSKLSADALEVKRYFVINERHG 999
EN PI T+++++ A D D G NG I Y + V Y ++ + V + N R
Sbjct: 261 ENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPVNSYFTIDAITG-VIRVAKTLDYNARDK 319
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEE 1056
H + + R + A +L +NI + + P F ++ Y F++ E
Sbjct: 320 HTLYISARDRGDPPRTSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIRE 379
Query: 1057 AQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
+ L + A D D G N L Y + + F I P +GV+++ +D E
Sbjct: 380 DFPPKGALLVMRAADNDPIGPNKRLRYSLSGNGVS-KFAIDPESGVVTLTDSVDYENTPN 438
Query: 1116 ---YILTVVARDNG-XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
Y LTV A D G D N NSP+F +LE
Sbjct: 439 NHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILE 486
Score = 68.1 bits (159), Expect = 2e-09
Identities = 73/276 (26%), Positives = 123/276 (44%), Gaps = 25/276 (9%)
Query: 150 DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF--QLVIMASGKR 207
D NTPN+ V+ V+ D G +L ++ + ++ ++ V D + F Q I+ +
Sbjct: 432 DYENTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDV-DENKNSPRFDPQQAILEISEN 490
Query: 208 IHKEILFPEPIHAIDQDLGVG------ATLRYELISGNDRKLFSLDSVNGSLFLEKELDL 261
+ + L + A D D VG + Y ++ G +F +DS G + + L
Sbjct: 491 LKQNSLVTT-VSATDSD-SVGNPSSPDGKVVYSIVGGTGLGVFRVDSNTGEVKVAVP-SL 547
Query: 262 DAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN 321
D E Q + L V+AS ++++ + I LLD +DN P F Y + EN P+
Sbjct: 548 DREGTSQ---YTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPS 604
Query: 322 GFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
G V V+ D D+G N +T + P + I+P +G +R LD+ S+ ++V
Sbjct: 605 GTFVTVVVGRDADEGFNPSYT--VITPGVPYKIEPSTG--VIRTSKSLDQSELSTRELQV 660
Query: 382 YAKETNPSVVGTFADSQ----RIAKWRRQPLETNAP 413
+ + AD Q I+K R P+ N P
Sbjct: 661 IVRVSTAG--SKTADGQVNITVISKVNRPPVFKNTP 694
Score = 67.3 bits (157), Expect = 3e-09
Identities = 86/348 (24%), Positives = 143/348 (41%), Gaps = 26/348 (7%)
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + VA+SL E + + L + G +++D +V V + D+ND P F Y +++E
Sbjct: 1271 GIISVAKSLDREKVAGYTLGMRVTLGQHVDDT-TVYVNLTDINDDAPHFTSAIYRRSIKE 1329
Query: 1057 A-QYTRRVLGKVDATDADFGQNANLTYFIQPS---DTDLPFEISPLTGVLSVNGELDRET 1112
+L V A D DFG N + Y I D D F I TG ++ LD ET
Sbjct: 1330 GLAEDTEILPPVIAVDHDFGSNGKILYSILSGVHPDWDKYFNIDSATGKITTKMTLDYET 1389
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
+ L + A DNG D NDNSP F A ++S
Sbjct: 1390 HKSHTLFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAF--------YRAKISLGA 1441
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILY--SLPQ-RKNQQNLG 1228
+ ++ V+ ++ T + + N+ + F N G+IL SL ++ +L
Sbjct: 1442 VKGTSVLQVHATDLDSGQNGQITYSIIQGNEEEAFTINEQGVILVDKSLTTVAADKFSLK 1501
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
+ + A V V + D P+F+ + ++E V A + + +
Sbjct: 1502 VEARDKNASPRSGSVTVEINVYLPDGPPMFVVSPVTVYVKEGVPANHRVAGVKAA---TS 1558
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ Y +L+ N+ + F I+P G+L R D E + YE+ + A
Sbjct: 1559 EALTYTLLSGNEAGM---FRINPSTGSLDATRELDYEERRRYELKIEA 1603
Score = 66.9 bits (156), Expect = 4e-09
Identities = 97/410 (23%), Positives = 179/410 (43%), Gaps = 44/410 (10%)
Query: 511 FKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKP 568
F+++ ++G + S E R+ L +EA S + + A +T+EVT +
Sbjct: 734 FEVDKDSGRLHTKNSFNYENVDRYNLRIEARTS----SVQEVASASLTVEVTE-----EK 784
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQ----IRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
D+P F Y+ V + GT++ I + + +Q D S + + F V +
Sbjct: 785 DLPKFSSDSYQLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLHTLYNFEVTQ 844
Query: 625 RSGV----ITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKG 679
+SG + L + Y F A N N+ V+V+DVND + L+
Sbjct: 845 QSGRCFLRVQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQE 904
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAIAEDGTI 738
++ + AG+++ + +M GT VR+ + Q++ ++ + ++ +
Sbjct: 905 SYWLSV--PSSTPAGSSLVTVQAEDMDI----GTNAQVRYELLRQEN-SERFILNDNNQL 957
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T L R Y++ + A + + V + + +++P VF+ ++Y + E
Sbjct: 958 STASTLTPNVR--YQLLIRASDSATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPE 1015
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDENTGVVKFIGDSLD 854
+S T + KAT + G+++ Y L G G+ MF + +TG V I LD
Sbjct: 1016 DSSANTLVFT---AKATRS--GSSSGITYELVGGYKQIGEAMFSIKPDTGQVYLI-KKLD 1069
Query: 855 REKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENSK 901
E K + +++ A+ +GG L+SE + I D NDN P F E+SK
Sbjct: 1070 FETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRF-AFHESSK 1118
Score = 66.9 bits (156), Expect = 4e-09
Identities = 84/309 (27%), Positives = 130/309 (42%), Gaps = 31/309 (10%)
Query: 91 NDNVPIFLDTPYHVTVDELTPTGEKAF-IFLIAPIGPSLTIPL--TVPRGLTIFK---DI 144
N+ P F Y +++E TG I + G ++ T PR +F+ D
Sbjct: 2462 NEEPPKFSQQVYTASINENMETGSTVTRITATSSTGAEISYENVDTNPRAKILFRVQPDG 2521
Query: 145 RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMAS 204
D+P+ Y++ D L S+ K V+ ++D + F L I
Sbjct: 2522 YIITGDRPDYERGTT-YNMQFAAKDKKTLLYSTVKVVI---NIIDVNDVSPAFLLAINTR 2577
Query: 205 GKRIHKEILFPEPI---HAIDQDLGVG-ATLRYELISGNDRKLFSLDSVNGSLFLEKELD 260
R+ + P + AID D + YE+ D F +D+ G + + LD
Sbjct: 2578 NARVLENKPAPTKVISMKAIDDDGSEPHRRVTYEM---KDNPNFQIDASTGMITTKTTLD 2634
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
+ + ++V A + + A + I ++D ND P F Y IS+ E+ P
Sbjct: 2635 REVTPK-----YDVEVTAK---DGVNKESAILYITVVDQNDQPPVFAPKSYAISVPEDSP 2686
Query: 321 NGFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSI--DPRSGWLTVRNQTVLDREAHSS 376
G SVL + ATD D GEN + TY + DP+G FSI P G L V + LD E SS
Sbjct: 2687 IGTSVLDIYATDADVGENAKITYFISKGDPEGKFSIVTSPVKGELVVNGK--LDFETKSS 2744
Query: 377 LRMKVYAKE 385
++V A +
Sbjct: 2745 YTLEVTATD 2753
Score = 64.1 bits (149), Expect = 3e-08
Identities = 66/224 (29%), Positives = 97/224 (43%), Gaps = 28/224 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G +++++ A D D G N + +EF V + + A F I+ +G
Sbjct: 3001 VAENAPPGYSVLRVTATDEDVGPNAE--FEF---VVVQGNDPHA--------FYIDPFNG 3047
Query: 1000 HVIVARSLPPES--EFRLNISALDGG----NLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
V+V+ L E E+ + ++ D G ++ V + + D ND+ P F YN +
Sbjct: 3048 TVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKIYNAS 3107
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISP-----LTGVLSVNGE 1107
V E R+ + V A D D G N N T+ I P SD D F I P G++
Sbjct: 3108 VLEDVGARQPVLTVTAVDKDSGPNGNFTFAIDPRSDPDDAFTIEPNPNNASIGIIRTRVP 3167
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD+E + L V A D G DVNDN P F
Sbjct: 3168 LDQEKTPSFHLKVTATDAG---GLQGEGEVRINVIDVNDNGPWF 3208
Score = 62.1 bits (144), Expect = 1e-07
Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 23/266 (8%)
Query: 892 EFNQIEENSKVRIHRETK--LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTT 949
E +Q + N KV+ + L+ T I + + F QL + IPE+ +G
Sbjct: 2000 ERDQTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFPYFDQQLYSV-QIPESTAVGVL 2058
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+ ++ A D D + F + I PSK E F I+ G + V+ +L
Sbjct: 2059 VQEVTAKDCDCLSSCTCSPGFLT-YSIEPSK------EQGGKFYIDPATGKISVSVALDY 2111
Query: 1010 ESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
E + L + A D G + V V + +VND+ P F K+ Y F V E T L
Sbjct: 2112 EDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEGAATGESLA 2171
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
V A DAD +TY + L F + TGV+++N LD +++Y L V+A+D+
Sbjct: 2172 IVVAVDAD---GDAVTY--SKAGGALQFSVDQSTGVITLNSALD-PNKNQYTLQVMAKDS 2225
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKF 1151
G D N+N P+F
Sbjct: 2226 G---GLTSTVSVTFNVADANNNVPQF 2248
Score = 61.3 bits (142), Expect = 2e-07
Identities = 60/191 (31%), Positives = 87/191 (45%), Gaps = 17/191 (8%)
Query: 940 IPENIPIGTTIIK-LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
I E + T I+ + A+D D G NG+I Y S V+ P + +YF I+
Sbjct: 1327 IKEGLAEDTEILPPVIAVDHDFGSNGKILYSILSGVH--P--------DWDKYFNIDSAT 1376
Query: 999 GHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + +L E+ L I A D G+ L+ V + V D ND+ PVF +Y
Sbjct: 1377 GKITTKMTLDYETHKSHTLFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAFYRAK 1436
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ + +V ATD D GQN +TY I + + F I+ GV+ V+ L
Sbjct: 1437 ISLGAVKGTSVLQVHATDLDSGQNGQITYSIIQGNEEEAFTINE-QGVILVDKSLTTVAA 1495
Query: 1114 DKYILTVVARD 1124
DK+ L V ARD
Sbjct: 1496 DKFSLKVEARD 1506
Score = 60.1 bits (139), Expect = 5e-07
Identities = 76/291 (26%), Positives = 127/291 (43%), Gaps = 23/291 (7%)
Query: 67 LVRIG-AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG 125
+VR+ AG +++TV I VN P+F +TPY V V E G +F IA +
Sbjct: 661 IVRVSTAGSKTADGQVNITV-ISKVN-RPPVFKNTPYSVKVPE--EMGPLPNLFCIAAVD 716
Query: 126 P-SLTIPLTVPRG----LTIFKDI-RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK 179
S + T+ G + KD R ++ N N D + + + S+
Sbjct: 717 SLSRPVQYTLAPGADGLFEVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVASASL 776
Query: 180 PVLLLR-KVLDYDAGDKEFQLVI---MASGKRIHKEILFPEPIHAIDQ-DLGVGATLRYE 234
V + K L + D +QL + A G + +L + + DQ D + A
Sbjct: 777 TVEVTEEKDLPKFSSDS-YQLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLH 835
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ F + +G FL + + +L A+ + V+A+ N A A+VE+
Sbjct: 836 TLYN-----FEVTQQSGRCFLRVQAGGKLDAHL-ASKYTFNVRATDRNFRNMFATAQVEV 889
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
++D+ND+ PEF + Y +S+ + P G S++ V A D D G N + Y+L
Sbjct: 890 NVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYEL 940
Score = 60.1 bits (139), Expect = 5e-07
Identities = 121/490 (24%), Positives = 179/490 (36%), Gaps = 76/490 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN P T I +L A D D G NGQI Y S + + F I R G
Sbjct: 2256 IRENDPRDTKITQLTATDADRGQNGQITY-------------SIEDASSQTLFSIEPRTG 2302
Query: 1000 HVIVARSLPPESEFRLN--ISALDGGNLNDNIS-------VRVFVKDVNDHFPVFKKTWY 1050
V SL E++ N I A DG + D + + V+DVND+ P F Y
Sbjct: 2303 VVRSLTSLDRENKDSYNAIIKAEDGSSKQDESERLLWYCYLTINVEDVNDNRPYFLAAKY 2362
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN---GE 1107
+V + + V ATDAD G NA + Y + S L F + +G+L N
Sbjct: 2363 FGSVFSSAPNGSNILTVQATDADSGSNAKIKYALLDSAGGL-FRLDS-SGILRTNTNPAR 2420
Query: 1108 LDRETEDKYILTVVARD----NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHP 1163
L ET K +L V A+D G N+ PKF
Sbjct: 2421 LQLETGKKLLLEVSAKDVESIAGTQPGKPTKYTTQIEILVSNEEPPKF---------SQQ 2471
Query: 1164 EADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD---FIGNGNGLILY-SLP 1219
N N E+ + AT A I + V N F +G I+ P
Sbjct: 2472 VYTASINENMETGSTVTRITATSSTGAEI--SYENVDTNPRAKILFRVQPDGYIITGDRP 2529
Query: 1220 --QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFI--SRYYELEIEENVNAPV 1274
+R N+ + +L TV V + ++++D P F+ + EN AP
Sbjct: 2530 DYERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPT 2589
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
+++S+ + + R D F ID G + + DREV Y+V V
Sbjct: 2590 KVISMKAIDDDGSEPHRRVTYEMKDNP---NFQIDASTGMITTKTTLDREVTPKYDVEVT 2646
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTT 1394
A+ +G+ K + + + D ND P F + ++P
Sbjct: 2647 AK--------------------DGVNKESAILYITVVDQNDQPPVF--APKSYAISVPED 2684
Query: 1395 APFGYQVMQL 1404
+P G V+ +
Sbjct: 2685 SPIGTSVLDI 2694
Score = 60.1 bits (139), Expect = 5e-07
Identities = 57/220 (25%), Positives = 95/220 (43%), Gaps = 21/220 (9%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++ ++ + A+D DSG NG + I P DA ++ N + +
Sbjct: 3110 EDVGARQPVLTVTAVDKDSGPNGNFTFA------IDPRSDPDDAFTIEP----NPNNASI 3159
Query: 1002 IVARS-LPPESE----FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ R+ +P + E F L ++A D G L VR+ V DVND+ P F ++ ++E
Sbjct: 3160 GIIRTRVPLDQEKTPSFHLKVTATDAGGLQGEGEVRINVIDVNDNGPWFVPPFFVGQIKE 3219
Query: 1057 AQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGV-----LSVNGELDR 1110
R+ + K+ A D D F ++ +T+ I F++ P++ L G DR
Sbjct: 3220 GVSARQFVTKLKAYDPDAFVKDQVITFSIYNGTVGENFKLDPVSVTNESVDLHSYGVFDR 3279
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
E + + + A DN DVNDN+PK
Sbjct: 3280 EAAPVWKIGIEAVDNVGPKPQKNFTYVYVDVLDVNDNAPK 3319
Score = 59.3 bits (137), Expect = 8e-07
Identities = 103/465 (22%), Positives = 183/465 (39%), Gaps = 41/465 (8%)
Query: 456 NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINP 515
+P+ + Y ++ ++ T++ KA G + + Y+L + F I P
Sbjct: 1000 SPIVFDKSSYNQNLPEDSSANTLVFTAKATRS--GSSSGITYELVGGYKQIGEAMFSIKP 1057
Query: 516 NTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMG 575
+TG V + + E + + + + + S V + + N P F
Sbjct: 1058 DTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKVTIV-DVNDNGPRFA-FHE 1115
Query: 576 APYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE-EGVPFAVEERSGVITVVDD 634
+ + S T + + D+ +V+Y + G +PF + ++G+I +
Sbjct: 1116 SSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRSTSNLPFNINVKTGMIFATRE 1175
Query: 635 LSRYNRPMYDFEAVALQENANLSI-VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA 693
+ Y VA + S + TV+V ++ R P F K SA
Sbjct: 1176 ILYTQGSSYIIIVVATDGATDGSQKIQKFTVNVQVLDTPR---------PPSFPQKTYSA 1226
Query: 694 G----AAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
A +G T + ++Y +++ ++ +D T + G I K LDREK
Sbjct: 1227 PVTETAGVGDTV-TTVRAVYSKPNAFLKYTFVSGNEDNT--FCVNGFGIISVAKSLDREK 1283
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHATYEGFIMENSKIGTEI 806
Y + + V G + T+Y+ D ND+ P F A Y I E TEI
Sbjct: 1284 VAGYTLGM------RVTLGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEI 1337
Query: 807 KMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
+ +I A D D G+N +Y++ + + F++D TG + +LD E +
Sbjct: 1338 -LPPVI-AVDHDFGSNGKILYSILSGVHPDWDKYFNIDSATGKIT-TKMTLDYETHKSHT 1394
Query: 863 LSLVARDTGG---LSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
L + A D G LS A++ I + D NDN P F +K+ +
Sbjct: 1395 LFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAFYRAKISL 1439
Score = 57.6 bits (133), Expect = 2e-06
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 15/166 (9%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
GA L Y+++SGN F + +G + L LD + + Q N L+V+A++
Sbjct: 1967 GARLDYKIVSGNVGDKF-IAMGDGRILLNSLLDFERDQT-QYN---LKVKATEQIPDGLD 2021
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-----QGENGEFT 342
+ V+I++++ ND+ P F+ Y++ I E+ G V +V A D D G T
Sbjct: 2022 STVDVKIDVINANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLT 2081
Query: 343 YQLDDPK---GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y ++ K G F IDP +G ++V LD E +KVYA +
Sbjct: 2082 YSIEPSKEQGGKFYIDPATGKISV--SVALDYEDQRYHLLKVYATD 2125
Score = 55.6 bits (128), Expect = 1e-05
Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 17/163 (10%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A L+Y +SGN+ F VNG + LD E + T ++V Q
Sbjct: 1250 AFLKYTFVSGNEDNTFC---VNGFGIISVAKSLDRE-KVAGYTLGMRVTLGQ-----HVD 1300
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL-QVMATDKDQGENGEFTYQL-- 345
V + L D+ND+ P F Y SI E L +L V+A D D G NG+ Y +
Sbjct: 1301 DTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSILS 1360
Query: 346 ---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D F+ID +G +T + LD E H S + + A++
Sbjct: 1361 GVHPDWDKYFNIDSATGKITTK--MTLDYETHKSHTLFIRAED 1401
Score = 54.8 bits (126), Expect = 2e-05
Identities = 63/209 (30%), Positives = 92/209 (44%), Gaps = 27/209 (12%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT++++++A DLDSG NGQI Y S + + E F INE+ G ++V +S
Sbjct: 1444 GTSVLQVHATDLDSGQNGQITY----------SIIQGNEEEA---FTINEQ-GVILVDKS 1489
Query: 1007 LPPES--EFRLNISALDGGNLNDNISVRVFVKD-VNDHFPVFKKTWYNFNVEEA-QYTRR 1062
L + +F L + A D + SV V + + D P+F + V+E R
Sbjct: 1490 LTTVAADKFSLKVEARDKNASPRSGSVTVEINVYLPDGPPMFVVSPVTVYVKEGVPANHR 1549
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
V G AT + LTY + + F I+P TG L ELD E +Y L + A
Sbjct: 1550 VAGVKAAT------SEALTYTLLSGNEAGMFRINPSTGSLDATRELDYEERRRYELKIEA 1603
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
RD ++NDN P F
Sbjct: 1604 RD---TRDRSAMVELIIIVVNINDNKPTF 1629
Score = 54.4 bits (125), Expect = 2e-05
Identities = 98/403 (24%), Positives = 160/403 (39%), Gaps = 41/403 (10%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISA-LDGG--NLNDNISVRVFVKDVNDHFPVFK 1046
F I G V + + L E++ F + + A GG L + +V + DVND+ P F
Sbjct: 1053 FSIKPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRFA 1112
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP--SDTDLPFEISPLTGVLSV 1104
+ V ++ + A DAD G +TY I S ++LPF I+ TG++
Sbjct: 1113 FHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRSTSNLPFNINVKTGMIFA 1172
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
E+ YI+ VVA D V D +P+ +F + + P
Sbjct: 1173 TREILYTQGSSYIIIVVATDG--ATDGSQKIQKFTVNVQVLD-TPRPPSFPQ-KTYSAP- 1227
Query: 1165 ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
E + + VY + NA + T D F NG G+I S+ + ++
Sbjct: 1228 VTETAGVGDTVTTVRAVYS---KPNAFLKYTFVS-GNEDNTFCVNGFGII--SVAKSLDR 1281
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMS----DKPVFISRYYELEIEENVNAPVELVSLN 1280
+ + +L L V D V ++ D P F S Y I+E + E++
Sbjct: 1282 EKVAGYTLGMRVTLGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPV 1341
Query: 1281 LTEHYE---NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ ++ N K+ Y IL+ D + F ID G + + D E ++ + +RAE
Sbjct: 1342 IAVDHDFGSNGKILYSILSGVHPDWDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAED 1401
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ L G+ + D+ V+ D NDNSP F
Sbjct: 1402 NGSPKR------------LSGIAQVDIDVI----DRNDNSPVF 1428
Score = 48.8 bits (111), Expect = 0.001
Identities = 88/361 (24%), Positives = 144/361 (39%), Gaps = 29/361 (8%)
Query: 774 TIYIE--DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
T+YI D D P AT E + EN I+ + + D E T F + +
Sbjct: 321 TLYISARDRGDPPRTSAEATVEISLREN------IQGWPLPDSADPKENTKPYFPQSRYT 374
Query: 832 EG-KEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD-END 888
+E F V++ D + K++ Y LS + E+ ++ + + +
Sbjct: 375 FSIREDFPPKGALLVMRAADNDPIGPNKRLRYSLSGNGVSKFAIDPESGVVTLTDSVDYE 434
Query: 889 NKPEFNQIEENSKVRIHRETKLNGTAGFTI-IEVKPKNKFALDVDQLGPLFLIPENIPIG 947
N P + + L+ T I I+ +NK + D + I EN+
Sbjct: 435 NTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQN 494
Query: 948 TTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA-RS 1006
+ + ++A D DS G VY S + L V F ++ G V VA S
Sbjct: 495 SLVTTVSATDSDSV--GNPSSPDGKVVY---SIVGGTGLGV---FRVDSNTGEVKVAVPS 546
Query: 1007 LPPE--SEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E S++ L + A D + + + + + D +D+FP F + Y V E Q +
Sbjct: 547 LDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGT 606
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
+ V DAD G N + T I P +P++I P TGV+ + LD+ L V+
Sbjct: 607 FVTVVVGRDADEGFNPSYT-VITPG---VPYKIEPSTGVIRTSKSLDQSELSTRELQVIV 662
Query: 1123 R 1123
R
Sbjct: 663 R 663
Score = 48.4 bits (110), Expect = 0.002
Identities = 67/299 (22%), Positives = 118/299 (39%), Gaps = 27/299 (9%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPR 136
A V V + DVND+ P FL Y ++V TP G IG + + + R
Sbjct: 883 ATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYELLR 942
Query: 137 GLT----IFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYD 191
I D TPN V Y + + +D S+ PV V Y
Sbjct: 943 QENSERFILNDNNQLSTASTLTPN--VRYQLLIRASDSATRNPSSAQVPVY----VSVYS 996
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDL-GVGATLRYELISGNDR---KLFSLD 247
+ + + + ++ + G + + YEL+ G + +FS+
Sbjct: 997 PSESPIVFDKSSYNQNLPEDSSANTLVFTAKATRSGSSSGITYELVGGYKQIGEAMFSIK 1056
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV-EIELLDLNDNLPEF 306
G ++L K+LD + + + F + V+A ++ A V ++ ++D+NDN P F
Sbjct: 1057 PDTGQVYLIKKLDFETK-----SYFPIAVRAKYSGGAIELASEVVAKVTIVDVNDNGPRF 1111
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPRSGWL 361
+ ++V + + A D D G GE TY +D + F+I+ ++G +
Sbjct: 1112 AFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRSTSNLPFNINVKTGMI 1170
Score = 47.6 bits (108), Expect = 0.003
Identities = 94/417 (22%), Positives = 163/417 (39%), Gaps = 48/417 (11%)
Query: 418 TYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT 477
T V DK K E + V VE+ + D P+FV S + + +K
Sbjct: 1491 TTVAADKFSLKVEARDKNASPRSGSVTVEINVY-LPDGPPMFVVSPVTVY-VKEGVPANH 1548
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALF 535
+ VKA + + Y L + + F+INP+TG++ E R + L
Sbjct: 1549 RVAGVKAATSEA-----LTYTLLSGNEAGM---FRINPSTGSLDATRELDYEERRRYELK 1600
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW-VGSNVGIGTSVGQ 594
+EA D R S V I + NKP D + + +G+ + G+
Sbjct: 1601 IEARDT------RDRSAMVELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGE 1654
Query: 595 IRVN-DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN 653
+ AF+++ + + F ++ R GV+T + + +Y F AL +N
Sbjct: 1655 VITRLGAFDRDGDEITFIVPDDVKDLFKIDSR-GVVTAKKPIEDLPK-IYPFNVKAL-DN 1711
Query: 654 ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNG 712
T+ V +V V+ + P HV+ N G + T + + NG
Sbjct: 1712 GEPPQETDVKVRLVFVH----------YRPDQKHVRVNVREDTPTGSVIAT-VRRYFPNG 1760
Query: 713 TGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ 772
V L+ + + ++ +G + PLD E + +RMTV E +
Sbjct: 1761 I--VSLLLPEKAN----FSVRANGDVILLTPLDYESQQFHRMTVREELG----NQTNDVD 1810
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
V + + D NDN P++ + NS+ G ++ ++A D D+G++ L Y L
Sbjct: 1811 VEVVVLDVNDNRPIWMERERLARVNTNSRAGAQVYQ---LEARDEDDGSSGLVGYQL 1864
Score = 47.2 bits (107), Expect = 0.003
Identities = 69/280 (24%), Positives = 110/280 (39%), Gaps = 27/280 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDT---------PYHVTVDELTPT----GEKAFIFLIAP 123
+++ +SVT + D N+NVP F + P + +LT T G+ I
Sbjct: 2228 LTSTVSVTFNVADANNNVPQFTNCGTVSIRENDPRDTKITQLTATDADRGQNGQITYSIE 2287
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
S T+ PR + + + + DR+ ++ N+ + S D L +
Sbjct: 2288 DASSQTLFSIEPR-TGVVRSLTSLDRENKDSYNAIIKAEDGSSKQDESERLLWYCYLTIN 2346
Query: 184 LRKVLD---YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ V D Y K F V ++ IL + A D D G A ++Y L+
Sbjct: 2347 VEDVNDNRPYFLAAKYFGSVFSSAPNG--SNIL---TVQATDADSGSNAKIKYALLDSAG 2401
Query: 241 RKLFSLDSVNGSLFLEKE---LDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
LF LDS +G L L L+ L V++ P K + +IE+L
Sbjct: 2402 G-LFRLDS-SGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQPGKPTKYTTQIEIL 2459
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
N+ P+F Y SI EN+ G +V ++ AT E
Sbjct: 2460 VSNEEPPKFSQQVYTASINENMETGSTVTRITATSSTGAE 2499
Score = 44.4 bits (100), Expect = 0.024
Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 28/283 (9%)
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ G+LD KY V A D DVND+ P+F E
Sbjct: 853 VQAGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVI-DVNDHKPEF--LQESYWLS 909
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR 1221
P + + S++ + I NA + + + N FI N N + +
Sbjct: 910 VPSSTPAGS----SLVTVQAEDMDIGTNAQVRYELLRQ-ENSERFILNDNNQLSTASTLT 964
Query: 1222 KNQQNLGLPSLSSTAILMVTVADVPDEVEM---SDKP-VFISRYYELEIEENVNAPVELV 1277
N + L S +A + A VP V + S+ P VF Y + E+ +A +
Sbjct: 965 PNVRYQLLIRASDSATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSANTLVF 1024
Query: 1278 SLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ T + + Y ++ F I P G +YL++ D E K + + VRA
Sbjct: 1025 TAKATRSGSSSGITYELVGGYKQIGEAMFSIKPDTGQVYLIKKLDFETKSYFPIAVRA-- 1082
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
KYS +A +V+ +T I DVNDN P+F
Sbjct: 1083 -KYSGG----AIELASEVVAKVT---------IVDVNDNGPRF 1111
Score = 41.9 bits (94), Expect = 0.13
Identities = 37/135 (27%), Positives = 66/135 (48%), Gaps = 17/135 (12%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L Y L+SGN+ +F ++ GSL +ELD + + + L+++A + ++A
Sbjct: 1561 LTYTLLSGNEAGMFRINPSTGSLDATRELDYE-----ERRRYELKIEARDTRD--RSAMV 1613
Query: 291 RVEIELLDLNDNLPEF------EVDFYNISIVE--NLPNGFSVLQVMATDKDQGENGEFT 342
+ I ++++NDN P F ++D I ++ G + ++ A D+D G+ F
Sbjct: 1614 ELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRD-GDEITFI 1672
Query: 343 YQLDDPKGAFSIDPR 357
DD K F ID R
Sbjct: 1673 VP-DDVKDLFKIDSR 1686
Score = 41.9 bits (94), Expect = 0.13
Identities = 84/383 (21%), Positives = 151/383 (39%), Gaps = 38/383 (9%)
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
P+K + + + + +L + V+ + + DAND+ P F Y S+ NA G + +
Sbjct: 2955 PNKFKVRVKATDAGNPRLSASVDGIIHVSDANDHKPKFT-EKFYRGSVAENAPPGYSVLR 3013
Query: 482 VKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEAS 539
V A D D+G N + + + ++ F I+P GTV V+ E + + + + +
Sbjct: 3014 VTATDEDVGPNAEFEFVVVQGND---PHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVA 3070
Query: 540 DQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV-- 597
D+ P + A V IE+ + P+F+ Y V +VG V +
Sbjct: 3071 DRGMPPLQGD-ETAYVVIEILDA----NDNAPEFIPKIYNASVLEDVGARQPVLTVTAVD 3125
Query: 598 NDAFEQNDVSYDLLHGYEEGVPFAVEERS-----GVITVVDDLSRYNRPMYDFEAVALQE 652
D+ + ++ + + F +E G+I L + P + + A +
Sbjct: 3126 KDSGPNGNFTFAIDPRSDPDDAFTIEPNPNNASIGIIRTRVPLDQEKTPSFHLKVTA-TD 3184
Query: 653 NANLSIVTNATVHVVDVNDER---------GVLLKGAHS-PIIFHVKENSAGAAIGQIFH 702
L ++V+DVND G + +G + + +K A +
Sbjct: 3185 AGGLQGEGEVRINVIDVNDNGPWFVPPFFVGQIKEGVSARQFVTKLKAYDPDAFVKDQVI 3244
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNK 762
T SIY NGT F + + VT++ +F DRE V+++ + A N
Sbjct: 3245 T--FSIY-NGTVGENFKL-DPVSVTNESVDLHSYGVF-----DREAAPVWKIGIEAVDNV 3295
Query: 763 GVISGAGIYQVTIYIEDENDNPP 785
G V + + D NDN P
Sbjct: 3296 GPKPQKNFTYVYVDVLDVNDNAP 3318
Score = 39.9 bits (89), Expect = 0.53
Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 1011 SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
S++ N+ A D N+ V V V DVNDH P F + Y +V + L V
Sbjct: 865 SKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVTVQ 924
Query: 1069 ATDADFGQNANLTY 1082
A D D G NA + Y
Sbjct: 925 AEDMDIGTNAQVRY 938
Score = 39.9 bits (89), Expect = 0.53
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 20/180 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D+G A +RYEL+ + + F L+ N L L + + L +++
Sbjct: 923 VQAEDMDIGTNAQVRYELLRQENSERFILND-NNQLSTASTLTPNVRYQL-----LIRAS 976
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK--DQ 335
S NP +AQ V + + +++ F+ YN +NLP S ++ T K
Sbjct: 977 DSATRNP-SSAQVPVYVSVYSPSESPIVFDKSSYN----QNLPEDSSANTLVFTAKATRS 1031
Query: 336 GENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
G + TY+L + FSI P +G + + + LD E S + V AK + ++
Sbjct: 1032 GSSSGITYELVGGYKQIGEAMFSIKPDTGQVYLIKK--LDFETKSYFPIAVRAKYSGGAI 1089
Score = 38.7 bits (86), Expect = 1.2
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 14/140 (10%)
Query: 998 HGHVIVARSLPPESE-FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+G VI+ L ES+ F + GN +++ V V V DVND+ P++ + V
Sbjct: 1777 NGDVILLTPLDYESQQFHRMTVREELGNQTNDVDVEVVVLDVNDNRPIWMERERLARVNT 1836
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL----------PFEISPLTGVLSVNG 1106
+ +++A D D G + + Y ++ D PF I+P T + V G
Sbjct: 1837 NSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDAKRKRRSPPQHPFTINPKTRQMEVAG 1896
Query: 1107 ELDRETEDKYILTVVARDNG 1126
L + +Y L V A D G
Sbjct: 1897 SL---KDQRYDLDVFAFDYG 1913
Score = 38.7 bits (86), Expect = 1.2
Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
NG + L LD +++ F +L N +T VE+ +LD+NDN P +
Sbjct: 1777 NGDVILLTPLDYESQQ------FHRMTVREELGN--QTNDVDVEVVVLDVNDNRPIWMER 1828
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
+ N G V Q+ A D+D G +G YQL P
Sbjct: 1829 ERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSP 1867
Score = 37.5 bits (83), Expect = 2.8
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 8/122 (6%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F +D G + + LD + + +L+V A+ V + L ++NDN
Sbjct: 2094 FYIDPATGKISVSVALDYEDQRY-----HLLKVYATDKGKKSFQGLCFVNVTLTNVNDNR 2148
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTV 363
P F Y + E G S+ V+A D D TY FS+D +G +T+
Sbjct: 2149 PTFLKSAYEFRVAEGAATGESLAIVVAVDAD---GDAVTYSKAGGALQFSVDQSTGVITL 2205
Query: 364 RN 365
+
Sbjct: 2206 NS 2207
>UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1;
Oikopleura dioica|Rep: Protocadherin 10-like protein -
Oikopleura dioica (Tunicate)
Length = 900
Score = 108 bits (259), Expect = 1e-21
Identities = 119/501 (23%), Positives = 208/501 (41%), Gaps = 51/501 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
+Q + N+ + +LD NDN+P F S + S+ +A++GT++ A D D Q +
Sbjct: 188 QQFFNVFNIRLLILDLNDNSPKFSEST-FHLSLPESAEIGTILRLSPATDDDTFQYQVKK 246
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE-------GRHALFVEASDQPANPSERR 549
Y L+ FKI N+G + + ++ RH L + A D E
Sbjct: 247 YFLESEQKPIF---FKIAENSGNFQIPQVELIRELDVNKRARHVLKIIAEDGGGRRGE-- 301
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD 609
A + IE+ + P F + + V N I + + + +DA ++ +
Sbjct: 302 ---AELIIEI----EDINDHSPIFESSQIKVDVSENASIASQITTLYASDA--DKGINGE 352
Query: 610 LLHGYEEGV-PFAVEER------SGVITVVDDLSRYNRPMYDFEAVALQENANLS-IVTN 661
+++ ++E V P +V E+ +G +T+ L + + A + S T
Sbjct: 353 VVYSFQENVNPISVTEKFNLNRSTGELTIAKSLDFESAEKFVLHVKAEDKGVGSSPAYTT 412
Query: 662 ATVHVVDVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
++++D ND + + S ++ GA I + ++ + + I
Sbjct: 413 VVINLIDENDNSPQIRISWLGSAPEKIAEDADLGAYIALV------NVQDDDNDEIHLEI 466
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
N D + + T+ LDRE+ Y + +IA + G I + I +ED
Sbjct: 467 QNSSDFELENNSRNRYILKTKSYLDRERIKNYNLKLIAR-DSGFPVRETIENLKIIVEDV 525
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
NDN P F H Y I EN++ G I I A D DEG NA Y L + +F++D
Sbjct: 526 NDNAPFFRHGQYNVHIDENNEPGAVILQ---ILAEDQDEGQNAELSYAL-DDSSGLFEID 581
Query: 841 ENTGVVKFIGDSLDREKKI----MYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
G + + +S+D EK ++A D G LS E+ + I D N+ +P F
Sbjct: 582 SENGNIIAL-ESIDAEKHTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQPSF- 639
Query: 895 QIEENSKVRIHRETKLNGTAG 915
+ N I + +K+ + G
Sbjct: 640 -MSRNYNFSIEKNSKIGASVG 659
Score = 72.9 bits (171), Expect = 6e-11
Identities = 101/407 (24%), Positives = 171/407 (42%), Gaps = 51/407 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIR-YEFNSE---VYIPPSKLSAD----ALEVKRY 991
+PE+ IGT I++L+ D Q++ Y SE ++ ++ S + +E+ R
Sbjct: 219 LPESAEIGT-ILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQIPQVELIRE 277
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+N+R HV L I A DGG + + ++D+NDH P+F+ +
Sbjct: 278 LDVNKRARHV-------------LKIIAEDGGGRRGEAELIIEIEDINDHSPIFESSQIK 324
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ----PSDTDLPFEISPLTGVLSVNGE 1107
+V E + + A+DAD G N + Y Q P F ++ TG L++
Sbjct: 325 VDVSENASIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTIAKS 384
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LD E+ +K++L V A D G D NDNSP+ + W ++
Sbjct: 385 LDFESAEKFVLHVKAEDKG-VGSSPAYTTVVINLIDENDNSPQI-----RISWLGSAPEK 438
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG-NGLIL----YSLPQRK 1222
++ + + I + ++N I + ++D + N N IL Y +R
Sbjct: 439 IA-EDADLGAYIALVNVQDDDNDEIHLEIQN--SSDFELENNSRNRYILKTKSYLDRERI 495
Query: 1223 NQQNLGLPSLSSTAILMVTVADVPDEVE-MSDK-PVFISRYYELEIEENVNAPVELVSLN 1280
NL L + S + T+ ++ VE ++D P F Y + I+EN N P ++
Sbjct: 496 KNYNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDEN-NEPGAVILQI 554
Query: 1281 LTEHY---ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
L E +N ++ Y + D F ID NG + + S D E
Sbjct: 555 LAEDQDEGQNAELSYAL-----DDSSGLFEIDSENGNIIALESIDAE 596
Score = 71.7 bits (168), Expect = 1e-10
Identities = 58/182 (31%), Positives = 93/182 (51%), Gaps = 20/182 (10%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA----GIYQVTIYIEDENDNPPVFE 788
A G + T+K +DREK + E V++ ++ + + I D NDN P F
Sbjct: 154 AHSGDLTTKKEIDREKICGIKKECALEIE--VLASPQQFFNVFNIRLLILDLNDNSPKFS 211
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF-DVDENTG--- 844
+T+ + E+++IGT +++ ATD D + Y L E K +F + EN+G
Sbjct: 212 ESTFHLSLPESAEIGTILRLS---PATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQ 268
Query: 845 --VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
V+ I + LD K+ + L ++A D GG EAELII I D ND+ P F E+S++
Sbjct: 269 IPQVELIRE-LDVNKRARHVLKIIAEDGGGRRGEAELIIEIEDINDHSPIF----ESSQI 323
Query: 903 RI 904
++
Sbjct: 324 KV 325
Score = 70.1 bits (164), Expect = 4e-10
Identities = 48/165 (29%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 221 IDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV------- 273
I +D +GA + + +D L+ N S F E E + + L+ +++
Sbjct: 439 IAEDADLGAYIALVNVQDDDNDEIHLEIQNSSDF-ELENNSRNRYILKTKSYLDRERIKN 497
Query: 274 --LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
L++ A P++ ++I + D+NDN P F YN+ I EN G +LQ++A
Sbjct: 498 YNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAE 557
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
D+D+G+N E +Y LDD G F ID +G + +D E H++
Sbjct: 558 DQDEGQNAELSYALDDSSGLFEIDSENGNIIALES--IDAEKHTN 600
Score = 64.5 bits (150), Expect = 2e-08
Identities = 55/201 (27%), Positives = 87/201 (43%), Gaps = 20/201 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+++ + D NDN P F Y + N + G VI ++ A D D GQN + Y L +S
Sbjct: 517 NLKIIVEDVNDNAPFFRHGQ-YNVHIDENNEPGAVILQILAEDQDEGQNAELSYALDDSS 575
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR-----HALFVEASDQPANPSERRYSLAVVTIE 558
L F+I+ G + ES E F+ + PS ++ V I
Sbjct: 576 GL-----FEIDSENGNIIALESIDAEKHTNGTDFVSFIIIASDHGQPSLSGFTEVKVFIN 630
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ P FM Y F + N IG SVGQ+ ND + + + L E +
Sbjct: 631 DLNEFQ------PSFMSRNYNFSIEKNSKIGASVGQLEANDMDKTAKMHFSL---ERENL 681
Query: 619 PFAVEERSGVITVVDDLSRYN 639
PF++ +R+G I++ L ++
Sbjct: 682 PFSINDRTGEISLSRSLLNFS 702
Score = 60.1 bits (139), Expect = 5e-07
Identities = 48/147 (32%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQV 276
I A DQD G A L Y L + LF +DS NG++ + +D AE + FV +
Sbjct: 554 ILAEDQDEGQNAELSYALDDSSG--LFEIDSENGNIIALESID--AEKHTNGTDFVSFII 609
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
AS P + V++ + DLN+ P F YN SI +N G SV Q+ A D D
Sbjct: 610 IASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGASVGQLEANDMD-- 667
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTV 363
+ + + L+ FSI+ R+G +++
Sbjct: 668 KTAKMHFSLERENLPFSINDRTGEISL 694
Score = 55.2 bits (127), Expect = 1e-05
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 34/218 (15%)
Query: 995 NERHGHVIVARS-LPPE--SEFRLNISALDGG-NLNDNI-SVRVFVKDVNDHFPVFKKTW 1049
N R+ +++ +S L E + L + A D G + + I ++++ V+DVND+ P F+
Sbjct: 477 NSRNRYILKTKSYLDRERIKNYNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQ 536
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD--TDLPFEISPLTGVLSVNGE 1107
YN +++E V+ ++ A D D GQNA L+Y + S ++ E + + S++ E
Sbjct: 537 YNVHIDENNEPGAVILQILAEDQDEGQNAELSYALDDSSGLFEIDSENGNIIALESIDAE 596
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
D ++A D+G D+N+ P F +
Sbjct: 597 KHTNGTDFVSFIIIASDHG-QPSLSGFTEVKVFINDLNEFQPSFMS-------------- 641
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
N+NF +IE+N+ IG +V ++ AND D
Sbjct: 642 -RNYNF-----------SIEKNSKIGASVGQLEANDMD 667
Score = 51.6 bits (118), Expect = 2e-04
Identities = 47/177 (26%), Positives = 84/177 (47%), Gaps = 27/177 (15%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN G I+++ A D D G N ++ Y + + F I+ +G
Sbjct: 541 IDENNEPGAVILQILAEDQDEGQNAELSYALDDSSGL---------------FEIDSENG 585
Query: 1000 HVIVARSLPPE-----SEF-RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
++I S+ E ++F I A D G +L+ V+VF+ D+N+ P F YN
Sbjct: 586 NIIALESIDAEKHTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYN 645
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
F++E+ +G+++A D D + A + + ++ +LPF I+ TG +S++ L
Sbjct: 646 FSIEKNSKIGASVGQLEANDMD--KTAKMHFSLERE--NLPFSINDRTGEISLSRSL 698
Score = 51.2 bits (117), Expect = 2e-04
Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L F V+V + D N+ P F+ N Y FS++ N+K+G +G+++A D D + + +
Sbjct: 619 LSGFTEVKVFINDLNEFQPSFMSRN-YNFSIEKNSKIGASVGQLEANDMD--KTAKMHFS 675
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES 525
L+R NL PF IN TG +S++ S
Sbjct: 676 LER-ENL----PFSINDRTGEISLSRS 697
Score = 48.8 bits (111), Expect = 0.001
Identities = 93/402 (23%), Positives = 169/402 (42%), Gaps = 68/402 (16%)
Query: 1010 ESEFRLNISALDGGNLNDNI-SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+ E L I L N+ ++R+ + D+ND+ P F ++ ++ ++ E+ +L
Sbjct: 174 KKECALEIEVLASPQQFFNVFNIRLLILDLNDNSPKFSESTFHLSLPESAEIGTILRLSP 233
Query: 1069 ATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN-----GELDRETEDKYILTVVAR 1123
ATD D Q YF++ + F+I+ +G + ELD +++L ++A
Sbjct: 234 ATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQIPQVELIRELDVNKRARHVLKIIAE 293
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D G D+ND+SP F E+ ++ K
Sbjct: 294 DGG---GRRGEAELIIEIEDINDHSPIF------------ESSQI--------------K 324
Query: 1184 ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
+ ENA I + + ++A+D D NG ++YS + N ++ + + +T+A
Sbjct: 325 VDVSENASIASQITTLYASDAD--KGINGEVVYSFQENVNPISVTEKFNLNRSTGELTIA 382
Query: 1244 DVPD---------EVEMSDKPVFISRYYELE----IEENVNAPVELVSL--NLTEHY-EN 1287
D V+ DK V S Y I+EN N+P +S + E E+
Sbjct: 383 KSLDFESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAED 442
Query: 1288 FKMRYYI--LNENDTDIRRTFVIDPRNGTLYLV--RSPDREVKDTYEVIVRAERQKYSRE 1343
+ YI +N D D ++ +N + + + S +R + T + R + Y+ +
Sbjct: 443 ADLGAYIALVNVQDDD-NDEIHLEIQNSSDFELENNSRNRYILKTKSYLDRERIKNYNLK 501
Query: 1344 L--PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
L +PV E T ++K++V +DVNDN+P F +G
Sbjct: 502 LIARDSGFPVRE------TIENLKIIV--EDVNDNAPFFRHG 535
Score = 44.8 bits (101), Expect = 0.018
Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 17/177 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGND----RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
++A D D G+ + Y + + F+L+ G L + K LD ++ A FV
Sbjct: 340 LYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTIAKSLDFES-----AEKFV 394
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS---IVENLPNGFSVLQVMA 330
L V+A A V I L+D NDN P+ + + + I E+ G + V
Sbjct: 395 LHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAEDADLGAYIALVNV 454
Query: 331 TDKDQGENGEFTYQLDDPKGAFSIDPRS-GWLTVRNQTVLDREAHSSLRMKVYAKET 386
D D N E ++ + F ++ S ++ ++ LDRE + +K+ A+++
Sbjct: 455 QDDD---NDEIHLEIQN-SSDFELENNSRNRYILKTKSYLDRERIKNYNLKLIARDS 507
Score = 44.0 bits (99), Expect = 0.032
Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 4/136 (2%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEK-ELDLDAEHNLQANTFVLQVQA 278
A D D +Y L S F + +G+ + + EL + + N +A VL++ A
Sbjct: 234 ATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQIPQVELIRELDVNKRAR-HVLKIIA 292
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+ +A + IE+ D+ND+ P FE + + EN + + A+D D+G N
Sbjct: 293 EDGGG--RRGEAELIIEIEDINDHSPIFESSQIKVDVSENASIASQITTLYASDADKGIN 350
Query: 339 GEFTYQLDDPKGAFSI 354
GE Y + S+
Sbjct: 351 GEVVYSFQENVNPISV 366
Score = 42.3 bits (95), Expect = 0.099
Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA-R 291
+++I G + + +D+ +G L +KE+D + ++ L+++ L +P +
Sbjct: 139 FKIIEGQNHEYLEIDAHSGDLTTKKEIDREKICGIKKEC-ALEIEV--LASPQQFFNVFN 195
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ + +LDLNDN P+F +++S+ E+ G + ATD D
Sbjct: 196 IRLLILDLNDNSPKFSESTFHLSLPESAEIGTILRLSPATDDD 238
>UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep:
Protocadherin - Aedes aegypti (Yellowfever mosquito)
Length = 605
Score = 108 bits (259), Expect = 1e-21
Identities = 111/373 (29%), Positives = 168/373 (45%), Gaps = 27/373 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ V +T+ D NDN P+F S Y ++ NA +GT + +V A D D G+NGMV Y + R
Sbjct: 240 MTVNITIQDVNDNQPIFNQSR-YFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRR 298
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F+I+PNTG +SV + E + H L V A D+ P E + A V+I VT
Sbjct: 299 QS-DKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLE---TTAFVSIRVT 354
Query: 561 RGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVND---AFEQNDVSYDLLHGYEE 616
N+P I F+ + + G V +I VND E ++V+ L G E
Sbjct: 355 -DVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGG--E 411
Query: 617 GVPFAVEERSGVITVVD---DLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDE 672
G F + R +I +V L R +P Y VA N L + V D+ND
Sbjct: 412 G-HFGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDN 470
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
K + + V + G ++ Q+ T + GN + L+ + I
Sbjct: 471 APEFEKEIYHANVMEVAD--PGTSVIQV--TAIDKDEGNNSAIAYSLLDTPDTHSQWFQI 526
Query: 733 -AEDGTIFTQKPLDREKRDVYRMTVIAEFNK-GVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ G I T+ +D E V ++ V+A+ N +S G VTI+ D NDN P+F+ +
Sbjct: 527 DSNSGLITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIH--DVNDNEPIFDQS 584
Query: 791 TYEGFIMENSKIG 803
Y + EN G
Sbjct: 585 FYNVSVAENEPKG 597
Score = 95.1 bits (226), Expect = 1e-17
Identities = 120/479 (25%), Positives = 195/479 (40%), Gaps = 35/479 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ-- 500
V V + +LD NDN P F P+ L N A D DLG+ Y++
Sbjct: 128 VRVVIRVLDENDNAPTF-PTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNIVSG 186
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVT 556
+N S + + + + L+ ++L VEA D NP R +T
Sbjct: 187 NVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYSLVVEALDG-GNPPLRGQMTVNIT 245
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--AFEQNDVSYDLLHGY 614
I+ + P F + Y V N IGT+V Q+ D A E V Y +
Sbjct: 246 IQDVNDNQ------PIFNQSRYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQ 299
Query: 615 -EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
++ F ++ +G+I+V L + +++ VA L ++ V DVND
Sbjct: 300 SDKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDN 359
Query: 673 RGVL----LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ ++ L +P I + A + + + Y N + + T
Sbjct: 360 QPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGEGHFGLTTR 419
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
D I + PLDRE + Y ++V+A + G + + + D NDN P FE
Sbjct: 420 DNIIY---LVIVSLPLDREIKPNYTLSVVAT-DTGNPPLHAAKTIFLTVTDINDNAPEFE 475
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGV 845
Y +ME + GT + + A D DEG N+ Y+L + F +D N+G+
Sbjct: 476 KEIYHANVMEVADPGTSVIQ---VTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNSGL 532
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ +D E + +L +VA+D G +SS +++ I D NDN+P F+Q N V
Sbjct: 533 IT-TRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSV 590
Score = 95.1 bits (226), Expect = 1e-17
Identities = 122/456 (26%), Positives = 194/456 (42%), Gaps = 44/456 (9%)
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
PEN P A DLD G RY S +LS+ ++ + +G
Sbjct: 154 PENTPRDVKRTLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGVLYLDLQING- 212
Query: 1001 VIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+ R P + L + ALDGGN L ++V + ++DVND+ P+F ++ Y V E
Sbjct: 213 -FLDRETTPA--YSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQSRYFATVPENA 269
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ +V ATD D G+N + Y I + SD D F I P TG++SVN LD ET++ +
Sbjct: 270 TIGTTVLQVYATDQDAGENGMVEYAINRRQSDKDQMFRIDPNTGLISVNKPLDFETKELH 329
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L VVA+D G DVNDN P L + P+ E S E V
Sbjct: 330 ELVVVAKDRG-LQPLETTAFVSIRVTDVNDNQPIINVI-FLSDDATPKISE-SAQPGEFV 386
Query: 1177 MMIPVYKATIE-ENAPIGTTVAKVFAN-DTDFIGNGNGLILYSLP-QRKNQQN------- 1226
I V + E + + T++ + N L++ SLP R+ + N
Sbjct: 387 ARISVNDPDSKTEYSNVNVTLSGGEGHFGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVA 446
Query: 1227 --LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH 1284
G P L + + +TV D+ D +K ++ + +E+ + + +++ +++ E
Sbjct: 447 TDTGNPPLHAAKTIFLTVTDINDNAPEFEKEIYHANV--MEVADPGTSVIQVTAIDKDEG 504
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
N + Y +L+ DT + F ID +G + RA + +
Sbjct: 505 -NNSAIAYSLLDTPDTH-SQWFQIDSNSGL----------------ITTRAHIDCETDPV 546
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
P +I ++ M+ V+V I DVNDN P F
Sbjct: 547 PQLIVVAKDNGFPPMSSTGT-VLVTIHDVNDNEPIF 581
Score = 85.0 bits (201), Expect = 1e-14
Identities = 64/175 (36%), Positives = 87/175 (49%), Gaps = 14/175 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSV---NGSLFLEKELD--LDAEHNLQANTFVL 274
A D DLG T RY ++SGN F L S +G L+L+ +++ LD E + L
Sbjct: 168 ARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGVLYLDLQINGFLDRE---TTPAYSL 224
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V+A NP Q V I + D+NDN P F Y ++ EN G +VLQV ATD+D
Sbjct: 225 VVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQD 284
Query: 335 QGENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
GENG Y ++ D F IDP +G ++V LD E + V AK+
Sbjct: 285 AGENGMVEYAINRRQSDKDQMFRIDPNTGLISVNKP--LDFETKELHELVVVAKD 337
Score = 75.8 bits (178), Expect = 9e-12
Identities = 83/335 (24%), Positives = 140/335 (41%), Gaps = 27/335 (8%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPS 127
+ G + ++V + I+DVNDN PIF + Y TV E G G +
Sbjct: 229 LDGGNPPLRGQMTVNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQDAGEN 288
Query: 128 LTIPLTVPRGLTIFKDIRAFDRD-------KP-NTPNSDVHYSIVSGNDDGHFALESSHK 179
+ + R + + D + KP + ++H +V D G LE++
Sbjct: 289 GMVEYAINRRQSDKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETT-- 346
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGK--RIHKEIL---FPEPIHAIDQDLGVGATLRYE 234
+ +V D + ++ ++ +I + F I D D +
Sbjct: 347 -AFVSIRVTDVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNV 405
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+SG + F L + + ++L + L + ++ N + L V A+ NP A + +
Sbjct: 406 TLSGGEGH-FGLTTRDNIIYLVI-VSLPLDREIKPN-YTLSVVATDTGNPPLHAAKTIFL 462
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA--- 351
+ D+NDN PEFE + Y+ +++E G SV+QV A DKD+G N Y L D
Sbjct: 463 TVTDINDNAPEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQ 522
Query: 352 -FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F ID SG +T R +D E ++ V AK+
Sbjct: 523 WFQIDSNSGLITTRAH--IDCETDPVPQLIVVAKD 555
Score = 66.9 bits (156), Expect = 4e-09
Identities = 88/353 (24%), Positives = 150/353 (42%), Gaps = 47/353 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN IGTT++++ A D D+G NG + Y N + +D + F I+ G
Sbjct: 265 VPENATIGTTVLQVYATDQDAGENGMVEYAIN--------RRQSDK---DQMFRIDPNTG 313
Query: 1000 HVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFN-- 1053
+ V + L E++ L + A D G L V + V DVND+ P+ + + +
Sbjct: 314 LISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDAT 373
Query: 1054 --VEEAQYTRRVLGKVDATDADFG---QNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+ E+ + ++ D D N N+T L + + V+ V+ L
Sbjct: 374 PKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGEGHFGLTTRDNIIYLVI-VSLPL 432
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
DRE + Y L+VVA D G D+NDN+P+F E H E+
Sbjct: 433 DREIKPNYTLSVVATDTG-NPPLHAAKTIFLTVTDINDNAPEFEK-----EIYHANVMEV 486
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF--IGNGNGLILY---------S 1217
++ SV+ + N+ I ++ + + I + +GLI
Sbjct: 487 ADPG-TSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNSGLITTRAHIDCETDP 545
Query: 1218 LPQR-KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
+PQ ++ G P +SST ++VT+ DV D ++P+F +Y + + EN
Sbjct: 546 VPQLIVVAKDNGFPPMSSTGTVLVTIHDVND-----NEPIFDQSFYNVSVAEN 593
Score = 58.4 bits (135), Expect = 1e-06
Identities = 76/248 (30%), Positives = 103/248 (41%), Gaps = 29/248 (11%)
Query: 687 HVKEN--SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD-DIAIAED-GTIFTQK 742
HV+E S G IG ++G +G ++ D D+AI G I T+
Sbjct: 47 HVRELEVSEGVPIGHQIGFIGEFLHGVDSGPPYLIVPVPGSAVDTDLAIDHTTGEIRTKV 106
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
LDREKR Y + I +SG + +V I + DENDN P F A EN+
Sbjct: 107 LLDREKRASYSLVAIP------LSGENV-RVVIRVLDENDNAPTFPTALMNIEFPENTP- 158
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD---ENTGVVKF---IGDSLDR 855
++K + A D D G Y + G F + E GV+ I LDR
Sbjct: 159 -RDVKR-TLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGVLYLDLQINGFLDR 216
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
E Y L + A D G L + + I I D NDN+P FNQ R N T
Sbjct: 217 ETTPAYSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQ------SRYFATVPENAT 270
Query: 914 AGFTIIEV 921
G T+++V
Sbjct: 271 IGTTVLQV 278
Score = 56.8 bits (131), Expect = 4e-06
Identities = 75/278 (26%), Positives = 122/278 (43%), Gaps = 35/278 (12%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPI----FLDTPYHVTVDELTPTGEKAFIFLIAPIGP-- 126
GL + V++ + DVNDN PI FL + E GE F+ I+ P
Sbjct: 339 GLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDATPKISESAQPGE--FVARISVNDPDS 396
Query: 127 -----SLTIPLTVPRG---LT-----IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFA 173
++ + L+ G LT I+ I + D+ PN + S+V+ D G+
Sbjct: 397 KTEYSNVNVTLSGGEGHFGLTTRDNIIYLVIVSLPLDREIKPNYTL--SVVA-TDTGNPP 453
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVIM-ASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
L ++ K + L V D + EF+ I A+ + + AID+D G + +
Sbjct: 454 LHAA-KTIFLT--VTDINDNAPEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIA 510
Query: 233 YELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
Y L+ D + F +DS +G + +D + + Q L V A P ++
Sbjct: 511 YSLLDTPDTHSQWFQIDSNSGLITTRAHIDCETDPVPQ-----LIVVAKDNGFPPMSSTG 565
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
V + + D+NDN P F+ FYN+S+ EN P G +L+V
Sbjct: 566 TVLVTIHDVNDNEPIFDQSFYNVSVAENEPKGRCILKV 603
Score = 50.8 bits (116), Expect = 3e-04
Identities = 89/333 (26%), Positives = 132/333 (39%), Gaps = 36/333 (10%)
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEE--AQYTRRVLGKVDATDADFGQNANLTYFI 1084
+N+ V + V D ND+ P F N E + +R L A D D G+ Y I
Sbjct: 126 ENVRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLN--PARDLDLGRYNTQRYNI 183
Query: 1085 QPSDTDLPFEIS---PLTGV----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
+ + F +S GV L +NG LDRET Y L V A D G
Sbjct: 184 VSGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYSLVVEALDGG-NPPLRGQMTV 242
Query: 1138 XXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA 1197
DVNDN P F PE + +V+ + EN + +
Sbjct: 243 NITIQDVNDNQPIFNQSRYFA--TVPENATIGT----TVLQVYATDQDAGENGMVEYAIN 296
Query: 1198 KVFAN-DTDF-IGNGNGLILYSLP---QRKNQQNL-------GLPSLSSTAILMVTVADV 1245
+ ++ D F I GLI + P + K L GL L +TA + + V DV
Sbjct: 297 RRQSDKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDV 356
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRT 1305
D + + +F+S +I E+ P E V+ ++ + + K Y +N +
Sbjct: 357 NDNQPIIN-VIFLSDDATPKISESAQ-PGEFVA-RISVNDPDSKTEYSNVNVTLSGGEGH 413
Query: 1306 FVIDPRNGTLYL--VRSP-DREVKDTYEVIVRA 1335
F + R+ +YL V P DRE+K Y + V A
Sbjct: 414 FGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVA 446
Score = 45.2 bits (102), Expect = 0.014
Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 14/180 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK--LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
++A DQD G + Y + K +F +D G + + K LD + + L V +
Sbjct: 278 VYATDQDAGENGMVEYAINRRQSDKDQMFRIDPNTGLISVNKPLDFETKE-LHELVVVAK 336
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN----ISIVENLPNGFSVLQVMAT 331
+ Q PL+T A V I + D+NDN P V F + I E+ G V ++
Sbjct: 337 DRGLQ---PLETT-AFVSIRVTDVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVN 392
Query: 332 DKD-QGENGEFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKET-NP 388
D D + E L +G F + R + V LDRE + + V A +T NP
Sbjct: 393 DPDSKTEYSNVNVTLSGGEGHFGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNP 452
Score = 41.5 bits (93), Expect = 0.17
Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 15/125 (12%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT++I++ A+D D G N I Y S + P + ++F I+ G +
Sbjct: 490 GTSVIQVTAIDKDEGNNSAIAY---SLLDTPDTH--------SQWFQIDSNSGLITTRAH 538
Query: 1007 LPPESEF--RLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
+ E++ +L + A D G ++ +V V + DVND+ P+F +++YN +V E + R
Sbjct: 539 IDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSVAENEPKGR 598
Query: 1063 VLGKV 1067
+ KV
Sbjct: 599 CILKV 603
Score = 41.1 bits (92), Expect = 0.23
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGDDLVRIGA--GLNQISAYLSVTVYIEDVNDNVPIFLDTP 101
+DS+S + + C+ D L+ + G +S+ +V V I DVNDN PIF +
Sbjct: 526 IDSNSGLITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSF 585
Query: 102 YHVTVDELTPTG 113
Y+V+V E P G
Sbjct: 586 YNVSVAENEPKG 597
Score = 39.1 bits (87), Expect = 0.92
Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 8/117 (6%)
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
PL RV I +LD NDN P F NI EN P A D D G Y
Sbjct: 122 PLSGENVRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRY 181
Query: 344 QL--DDPKGAFSID---PRSG--WLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVG 392
+ + AF + R G +L ++ LDRE + + V A + NP + G
Sbjct: 182 NIVSGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYSLVVEALDGGNPPLRG 238
>UniRef50_UPI0000F1D9C2 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 825
Score = 107 bits (258), Expect = 2e-21
Identities = 73/217 (33%), Positives = 107/217 (49%), Gaps = 13/217 (5%)
Query: 686 FHVKENSAG---AAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
F V E AG IG++ HT+M G G ++++ + + + + G I K
Sbjct: 472 FFVIEEYAGPEPVLIGRL-HTDMD----RGDGRTKYVLRGEGAGSVFVIDEKTGNIHVTK 526
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE++D YR+ A ++ + Q I ++D NDNPPVFE Y + E + I
Sbjct: 527 PLDREEKDEYRLIATATDSQTERALEPSSQFIIRVQDINDNPPVFEEGPYSATVPEMANI 586
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYK 862
GT I A D G +A +YTL +G+ F VD TG+++ LDRE + Y
Sbjct: 587 GTSIIQVTASDADDPTYGNSARLVYTLV-QGQPHFSVDPQTGILRTAVPDLDREAQDQYL 645
Query: 863 LSLVARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
+ L A+D GGLS + + + D NDN P F Q
Sbjct: 646 VVLQAKDMGGHLGGLSGTTTVTVRLTDVNDNPPRFVQ 682
Score = 83.0 bits (196), Expect = 6e-14
Identities = 69/236 (29%), Positives = 112/236 (47%), Gaps = 14/236 (5%)
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVV 667
+L G G F ++E++G I V L R + Y A A ++ ++ + V
Sbjct: 503 VLRGEGAGSVFVIDEKTGNIHVTKPLDREEKDEYRLIATATDSQTERALEPSSQFIIRVQ 562
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDV 726
D+ND V +G +S + + + G +I Q+ ++ YGN V L+ Q
Sbjct: 563 DINDNPPVFEEGPYSATVPEMA--NIGTSIIQVTASDADDPTYGNSARLVYTLVQGQPHF 620
Query: 727 TDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNP 784
+ D + G + T P LDRE +D Y + + A+ G + G +G VT+ + D NDNP
Sbjct: 621 SVD---PQTGILRTAVPDLDREAQDQYLVVLQAKDMGGHLGGLSGTTTVTVRLTDVNDNP 677
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV 839
P F +++ + E + G E+ I ATDAD G NA YT+ GE + F++
Sbjct: 678 PRFVQSSWLFSVSELAVPGAEV---GRISATDADLGENAKLEYTILDGESGDTFNI 730
Score = 79.0 bits (186), Expect = 9e-13
Identities = 69/230 (30%), Positives = 106/230 (46%), Gaps = 18/230 (7%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
FVI+E+ G++ V + L E E+RL +A D L + + V+D+ND+ PVF+
Sbjct: 513 FVIDEKTGNIHVTKPLDREEKDEYRLIATATDSQTERALEPSSQFIIRVQDINDNPPVFE 572
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVL- 1102
+ Y+ V E + +V A+DAD +G +A L Y + F + P TG+L
Sbjct: 573 EGPYSATVPEMANIGTSIIQVTASDADDPTYGNSARLVYTLVQGQPH--FSVDPQTGILR 630
Query: 1103 SVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ +LDRE +D+Y++ + A+D G DVNDN P+F L
Sbjct: 631 TAVPDLDREAQDQYLVVLQAKDMGGHLGGLSGTTTVTVRLTDVNDNPPRFVQSSWLF--- 687
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
EL+ E V I A + ENA + T+ + DT I N
Sbjct: 688 --SVSELAVPGAE-VGRISATDADLGENAKLEYTILDGESGDTFNISGAN 734
Score = 64.5 bits (150), Expect = 2e-08
Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 13/183 (7%)
Query: 210 KEILFPEPIHA----IDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH 265
+E PEP+ D D G G T +Y L +F +D G++ + K LD + +
Sbjct: 476 EEYAGPEPVLIGRLHTDMDRGDGRT-KYVLRGEGAGSVFVIDEKTGNIHVTKPLDREEKD 534
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
+ + SQ L+ + + I + D+NDN P FE Y+ ++ E G S+
Sbjct: 535 EYR---LIATATDSQTERALEPSSQFI-IRVQDINDNPPVFEEGPYSATVPEMANIGTSI 590
Query: 326 LQVMATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
+QV A+D D G + Y L + FS+DP++G L LDREA + +
Sbjct: 591 IQVTASDADDPTYGNSARLVYTLVQGQPHFSVDPQTGILRTAVPD-LDREAQDQYLVVLQ 649
Query: 383 AKE 385
AK+
Sbjct: 650 AKD 652
Score = 55.6 bits (128), Expect = 1e-05
Identities = 53/182 (29%), Positives = 92/182 (50%), Gaps = 25/182 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE IGT+II++ A D D G NS ++L ++ + +F ++ + G
Sbjct: 580 VPEMANIGTSIIQVTASDADDPTYG------NS------ARLVYTLVQGQPHFSVDPQTG 627
Query: 1000 HVIVARSLPP-----ESEFRLNISALD-GGNL---NDNISVRVFVKDVNDHFPVFKKTWY 1050
I+ ++P + ++ + + A D GG+L + +V V + DVND+ P F ++ +
Sbjct: 628 --ILRTAVPDLDREAQDQYLVVLQAKDMGGHLGGLSGTTTVTVRLTDVNDNPPRFVQSSW 685
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT--GVLSVNGEL 1108
F+V E +G++ ATDAD G+NA L Y I ++ F IS V+ +N E+
Sbjct: 686 LFSVSELAVPGAEVGRISATDADLGENAKLEYTILDGESGDTFNISGANQEAVIILNKEM 745
Query: 1109 DR 1110
R
Sbjct: 746 IR 747
Score = 50.4 bits (115), Expect = 4e-04
Identities = 42/130 (32%), Positives = 58/130 (44%), Gaps = 8/130 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y L+ G FS+D G L DLD E Q +++ +QA
Sbjct: 598 ADDPTYGNSARLVYTLVQGQPH--FSVDPQTGILRTAVP-DLDREAQDQ---YLVVLQAK 651
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ L + V + L D+NDN P F + S+ E G V ++ ATD D GE
Sbjct: 652 DMGGHLGGLSGTTTVTVRLTDVNDNPPRFVQSSWLFSVSELAVPGAEVGRISATDADLGE 711
Query: 338 NGEFTYQLDD 347
N + Y + D
Sbjct: 712 NAKLEYTILD 721
Score = 50.0 bits (114), Expect = 5e-04
Identities = 32/114 (28%), Positives = 53/114 (46%), Gaps = 18/114 (15%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
FVID + G +++ + DRE KD Y +I A + E LE +++
Sbjct: 513 FVIDEKTGNIHVTKPLDREEKDEYRLIATATDSQ------------TERALEPSSQF--- 557
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
++R++D+NDN P F G P +P A G ++Q+ + PT + R
Sbjct: 558 -IIRVQDINDNPPVFEEG--PYSATVPEMANIGTSIIQVTASDADDPTYGNSAR 608
Score = 46.4 bits (105), Expect = 0.006
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 18/205 (8%)
Query: 509 SPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGN 566
S F I+ TG + V + E + + L A+D + S ++ ++ +
Sbjct: 511 SVFVIDEKTGNIHVTKPLDREEKDEYRLIATATDSQTERALEPSSQFIIRVQDIN----D 566
Query: 567 KPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGVP-FAVEE 624
P P F PY V IGTS+ Q+ +DA + S L++ +G P F+V+
Sbjct: 567 NP--PVFEEGPYSATVPEMANIGTSIIQVTASDADDPTYGNSARLVYTLVQGQPHFSVDP 624
Query: 625 RSGVI-TVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDVNDERGVLLKGA 680
++G++ T V DL R + Y A + LS T TV + DVND +
Sbjct: 625 QTGILRTAVPDLDREAQDQYLVVLQAKDMGGHLGGLSGTTTVTVRLTDVNDNPP---RFV 681
Query: 681 HSPIIFHVKENSA-GAAIGQIFHTN 704
S +F V E + GA +G+I T+
Sbjct: 682 QSSWLFSVSELAVPGAEVGRISATD 706
Score = 45.2 bits (102), Expect = 0.014
Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V V L D NDN P FV S+ + FS+ A G +G++ A D DLG+N + Y
Sbjct: 660 LSGTTTVTVRLTDVNDNPPRFVQSS-WLFSVSELAVPGAEVGRISATDADLGENAKLEYT 718
Query: 499 L 499
+
Sbjct: 719 I 719
Score = 40.3 bits (90), Expect = 0.40
Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 3/101 (2%)
Query: 1052 FNVEEAQYTRRVL-GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F +EE VL G++ TD D G + Y ++ F I TG + V LDR
Sbjct: 473 FVIEEYAGPEPVLIGRLH-TDMDRG-DGRTKYVLRGEGAGSVFVIDEKTGNIHVTKPLDR 530
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E +D+Y L A D+ D+NDN P F
Sbjct: 531 EEKDEYRLIATATDSQTERALEPSSQFIIRVQDINDNPPVF 571
Score = 39.9 bits (89), Expect = 0.53
Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 20/184 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV---DPDLGQNGMVLYDLQRTS 503
+ + D NDN PVF Y ++ A +GT I +V A DP G + ++Y L +
Sbjct: 559 IRVQDINDNPPVF-EEGPYSATVPEMANIGTSIIQVTASDADDPTYGNSARLVYTLVQGQ 617
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F ++P TG + A + + ++ + ++A D + L+ T
Sbjct: 618 -----PHFSVDPQTGILRTAVPDLDREAQDQYLVVLQAKDMGGHLG----GLSGTTTVTV 668
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGV 618
R T N + P F+ + + F V G VG+I DA E + Y +L G E G
Sbjct: 669 RLTDVN-DNPPRFVQSSWLFSVSELAVPGAEVGRISATDADLGENAKLEYTILDG-ESGD 726
Query: 619 PFAV 622
F +
Sbjct: 727 TFNI 730
>UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein
MGC146652; n=1; Xenopus tropicalis|Rep: Putative
uncharacterized protein MGC146652 - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 911
Score = 107 bits (258), Expect = 2e-21
Identities = 122/454 (26%), Positives = 199/454 (43%), Gaps = 33/454 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + +LD NDN PVF + Y+ ++ N + TV+ K+ A D D G N + Y ++
Sbjct: 228 ITIIVLDVNDNAPVFDQPS-YKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTS 286
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F +NPNTG + + E H LFV+A D + R+ ++ +EV
Sbjct: 287 TAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVD---GGTPRQEGRCLIQVEV-ED 342
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I F E V + IGT VG I V D + + + D+ G +PF +
Sbjct: 343 INDNSPEI-IFTSNANE--VPEDAPIGTVVGFITVRD--KDSGKNGDVQLGVSPDLPFKI 397
Query: 623 EERSGVITVV--DDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLLKG 679
+ ++V + L R P Y + A + LS T ++V DVND R V +
Sbjct: 398 QPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQS 457
Query: 680 AHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD---VTDDIAI-AE 734
++ H+KEN G + + T+ G+ + + +Q D V+ + I +
Sbjct: 458 VYNA---HIKENIEPGTLLCTVSATDPD--VGSNSDLTYSISESQIDGSSVSSFVFINSN 512
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN-PPVFEHATYE 793
G I+ Q+ D E+ V +T E + G V I+I D NDN P V +
Sbjct: 513 TGDIYAQRSFDYEQFQVLTITARVE-DSGSPKLFSNVSVHIFILDTNDNAPSVLYPGDSK 571
Query: 794 GFIMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLFGE-GKEMFDVDENTGVVKFI 849
GFI + KI + I A D D G NA Y + G+ +F++ + TG ++ I
Sbjct: 572 GFIAQ-EKIPQSASAGYLVTKISAIDPDSGHNAWLSYRVVEPIGQTLFEISQYTGEIRII 630
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
L+ + + L + D G + A + ++I
Sbjct: 631 RSFLEIDNTEQH-LVISVSDHGEPALSATVTVII 663
Score = 85.4 bits (202), Expect = 1e-14
Identities = 74/251 (29%), Positives = 109/251 (43%), Gaps = 21/251 (8%)
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
E +G+ TII V N A DQ + EN+P+ T ++KLNA DLD G+N +I
Sbjct: 219 EQPRSGSTLITII-VLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEI 277
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG- 1023
Y F+ + K F +N G + + + E + L + A+DGG
Sbjct: 278 SYLFDHHT----------STAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVDGGT 327
Query: 1024 -NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
++V V+D+ND+ P T V E V+G + D D G+N ++
Sbjct: 328 PRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKDSGKNGDVQL 387
Query: 1083 FIQPSDTDLPFEISPLTGVLSV--NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
+ P DLPF+I P S+ + LDRE +Y + + A D G
Sbjct: 388 GVSP---DLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLG-SPALSNQTVILLN 443
Query: 1141 XXDVNDNSPKF 1151
DVNDN P F
Sbjct: 444 VSDVNDNRPVF 454
Score = 83.4 bits (197), Expect = 4e-14
Identities = 92/354 (25%), Positives = 151/354 (42%), Gaps = 29/354 (8%)
Query: 589 GTSVGQIRVNDAFEQNDVSYDLL--HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE 646
GT VG + + D+ L G F V++++G +TV D + R +
Sbjct: 41 GTLVGNVAQDLGLNMADIEKRRLSLRSGANGRYFFVDQKTGALTVRDRIDRESLCGSSLS 100
Query: 647 AVA-LQENANLSI-VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
+ L+ + + + ++DVND L I + E A + T
Sbjct: 101 CLLPLELGIEKPFELFSVDIEILDVNDNSPSFLSDNQ---IIQIIEIFANPGVRFPLDTA 157
Query: 705 MSSIYG-NGTGNVR-----FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA 758
S G NG + F + +++ D IAE + +K LDRE++ + + + A
Sbjct: 158 EDSDVGINGINQYKINPNPFFSLSVKNLKDGTLIAE---LVLEKKLDREEKGQHELLLTA 214
Query: 759 EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
F+ G +G +TI + D NDN PVF+ +Y+ + EN + T + + ATD D
Sbjct: 215 -FDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMK---LNATDLD 270
Query: 819 EGTNA----LFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLS 874
EG NA LF + K +F ++ NTG + +I +D EK Y+L + A D G
Sbjct: 271 EGVNAEISYLFDHHTSTAAKGIFGLNPNTGEI-YIKGFVDFEKTHFYELFVKAVDGGTPR 329
Query: 875 SEAELIIM--IGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
E +I + D NDN PE I ++ + + + GF + K K
Sbjct: 330 QEGRCLIQVEVEDINDNSPEI--IFTSNANEVPEDAPIGTVVGFITVRDKDSGK 381
Score = 82.2 bits (194), Expect = 1e-13
Identities = 105/402 (26%), Positives = 166/402 (41%), Gaps = 41/402 (10%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--E 1012
A D D G+NG +Y+ N P S +K +I E +++ + L E +
Sbjct: 157 AEDSDVGINGINQYKIN-----PNPFFSLSVKNLKDGTLIAE----LVLEKKLDREEKGQ 207
Query: 1013 FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
L ++A DGG + + + + V DVND+ PVF + Y + E V+ K++AT
Sbjct: 208 HELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNAT 267
Query: 1071 DADFGQNANLTYFIQPSDTDLP---FEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
D D G NA ++Y + F ++P TG + + G +D E Y L V A D G
Sbjct: 268 DLDEGVNAEISYLFDHHTSTAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVDGG- 326
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIE 1187
D+NDNSP+ E PE + V I V
Sbjct: 327 TPRQEGRCLIQVEVEDINDNSPEIIFTSNANE--VPEDAPIGT----VVGFITVRDKDSG 380
Query: 1188 ENAPIGTTVAKVFANDTDFIGNGNGLILYS-LPQRKNQQ--------NLGLPSLSSTAIL 1238
+N + V+ N L+ L + K Q +LG P+LS+ ++
Sbjct: 381 KNGDVQLGVSPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVI 440
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYIL- 1295
++ V+DV D ++PVF Y I+EN+ L +++ T+ N + Y I
Sbjct: 441 LLNVSDVND-----NRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISE 495
Query: 1296 NENDTDIRRTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
++ D +FV I+ G +Y RS D E + R E
Sbjct: 496 SQIDGSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVE 537
Score = 81.4 bits (192), Expect = 2e-13
Identities = 61/215 (28%), Positives = 99/215 (46%), Gaps = 16/215 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ PIGT + + D DSG NG ++ + ++ P K+ RY ++ H
Sbjct: 359 VPEDAPIGTVVGFITVRDKDSGKNGDVQLGVSPDL---PFKIQPFK---NRYSLVTSEH- 411
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ R P+ +L S L L++ + + V DVND+ PVF ++ YN +++E
Sbjct: 412 ---LDREKTPQYTIQLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQSVYNAHIKENIE 468
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY--- 1116
+L V ATD D G N++LTY I S D +S + S G++ + Y
Sbjct: 469 PGTLLCTVSATDPDVGSNSDLTYSISESQID-GSSVSSFVFINSNTGDIYAQRSFDYEQF 527
Query: 1117 -ILTVVAR-DNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+LT+ AR ++ D NDN+P
Sbjct: 528 QVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAP 562
Score = 76.6 bits (180), Expect = 5e-12
Identities = 115/537 (21%), Positives = 218/537 (40%), Gaps = 44/537 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+ +V++ +LD NDN+P F+ N ++ A G A D D+G NG+
Sbjct: 110 EKPFELFSVDIEILDVNDNSPSFLSDNQIIQIIEIFANPGVRFPLDTAEDSDVGINGINQ 169
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y + +++ + V E + +G+H L + A D P +
Sbjct: 170 YKINPNPFFSLSVKNLKDGTLIAELVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLIT 229
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
++ ++V + P F Y+ + N+ + T V ++ D E ++SY
Sbjct: 230 IIVLDV-------NDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFD 282
Query: 612 HGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVD 668
H F + +G I + + Y+ A+ V V D
Sbjct: 283 HHTSTAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVDGGTPRQEGRCLIQVEVED 342
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ND ++ +++ + ++ G +G I + S G+V+ ++ D+
Sbjct: 343 INDNSPEIIFTSNANEV--PEDAPIGTVVGFITVRDKDS---GKNGDVQLGVS--PDLPF 395
Query: 729 DIAIAEDG-TIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPV 786
I ++ ++ T + LDREK Y + + A + +S + + + + D NDN PV
Sbjct: 396 KIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTV--ILLNVSDVNDNRPV 453
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-----GEGKEMF-DVD 840
F + Y I EN + GT + + ATD D G+N+ Y++ G F ++
Sbjct: 454 FSQSVYNAHIKENIEPGTLL---CTVSATDPDVGSNSDLTYSISESQIDGSSVSSFVFIN 510
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEE 898
NTG + + S D E+ + ++ D+G L S + I I D NDN P +
Sbjct: 511 SNTGDI-YAQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVLYPGD 569
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENI-PIGTTIIKLN 954
+ + + +AG+ + ++ A+D D +L + PIG T+ +++
Sbjct: 570 SKGFIAQEKIPQSASAGYLVTKIS-----AIDPDSGHNAWLSYRVVEPIGQTLFEIS 621
Score = 65.3 bits (152), Expect = 1e-08
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 16/155 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVN---GSLFLEKELD--LDAEHNLQANTFVL 274
A D D+G+ +Y++ N FSL N G+L E L+ LD E Q +
Sbjct: 157 AEDSDVGINGINQYKI---NPNPFFSLSVKNLKDGTLIAELVLEKKLDREEKGQHELLLT 213
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ P ++ + I +LD+NDN P F+ Y I++ ENLP V+++ ATD D
Sbjct: 214 AFDGGE--QP-RSGSTLITIIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLD 270
Query: 335 QGENGEFTYQLDD-----PKGAFSIDPRSGWLTVR 364
+G N E +Y D KG F ++P +G + ++
Sbjct: 271 EGVNAEISYLFDHHTSTAAKGIFGLNPNTGEIYIK 305
Score = 63.3 bits (147), Expect = 5e-08
Identities = 64/278 (23%), Positives = 114/278 (41%), Gaps = 23/278 (8%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+T+ + DVNDN P+F Y +T+ E P + + ++
Sbjct: 228 ITIIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTST 287
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIM 202
+ PNT +++ G E +H L + K +D +E + +I
Sbjct: 288 AAKGIFGLNPNT--GEIYIK-------GFVDFEKTHFYELFV-KAVDGGTPRQEGRCLIQ 337
Query: 203 ASGKRIHK---EILFPEPIHAIDQDLGVGATLRYELISGNDR-KLFSLD-SVNGSL---- 253
+ I+ EI+F + + +D +G + + + D K + V+ L
Sbjct: 338 VEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKDSGKNGDVQLGVSPDLPFKI 397
Query: 254 --FLEKELDLDAEHNLQANT--FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
F + + +EH + T + +Q+ AS L +P + Q + + + D+NDN P F
Sbjct: 398 QPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQS 457
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
YN I EN+ G + V ATD D G N + TY + +
Sbjct: 458 VYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISE 495
Score = 59.3 bits (137), Expect = 8e-07
Identities = 58/199 (29%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I ENI GT + ++A D D G N + Y S+ D V + IN G
Sbjct: 463 IKENIEPGTLLCTVSATDPDVGSNSDLTYSI--------SESQIDGSSVSSFVFINSNTG 514
Query: 1000 HVIVARSLPPESEFRLNISAL--DGGN--LNDNISVRVFVKDVNDHFP--VFKKTWYNFN 1053
+ RS E L I+A D G+ L N+SV +F+ D ND+ P ++ F
Sbjct: 515 DIYAQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVLYPGDSKGFI 574
Query: 1054 VEE----AQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTG-VLSVNGE 1107
+E + ++ K+ A D D G NA L+Y ++P L FEIS TG + +
Sbjct: 575 AQEKIPQSASAGYLVTKISAIDPDSGHNAWLSYRVVEPIGQTL-FEISQYTGEIRIIRSF 633
Query: 1108 LDRETEDKYILTVVARDNG 1126
L+ + +++++ V+ D+G
Sbjct: 634 LEIDNTEQHLVISVS-DHG 651
Score = 55.2 bits (127), Expect = 1e-05
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D GV A + Y S + +F L+ G ++++ +D + H + L
Sbjct: 264 LNATDLDEGVNAEISYLFDHHTSTAAKGIFGLNPNTGEIYIKGFVDFEKTH-----FYEL 318
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V+A P + + +++E+ D+NDN PE + E+ P G V + DKD
Sbjct: 319 FVKAVDGGTPRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKD 378
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+NG+ + P F I P ++ LDRE +++ A +
Sbjct: 379 SGKNGDVQLGV-SPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASD 428
Score = 53.6 bits (123), Expect = 4e-05
Identities = 74/305 (24%), Positives = 124/305 (40%), Gaps = 35/305 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----------APIGPSLTIPL 132
+ V +ED+NDN P + T V E P G + +G S +P
Sbjct: 336 IQVEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKDSGKNGDVQLGVSPDLPF 395
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA 192
+ + + + D+ TP + ++ +D G AL S++ V+LL V D +
Sbjct: 396 KIQPFKNRYSLVTSEHLDREKTPQYTIQ---LTASDLGSPAL--SNQTVILLN-VSDVND 449
Query: 193 GDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL----ISGNDRKLFS-L 246
F Q V A K + + A D D+G + L Y + I G+ F +
Sbjct: 450 NRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQIDGSSVSSFVFI 509
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE- 305
+S G ++ ++ D + Q T +V+ S +P + V I +LD NDN P
Sbjct: 510 NSNTGDIYAQRSFDYE---QFQVLTITARVEDS--GSPKLFSNVSVHIFILDTNDNAPSV 564
Query: 306 -FEVDFYNISIVENLPN----GFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRS 358
+ D E +P G+ V ++ A D D G N +Y++ +P G F I +
Sbjct: 565 LYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHNAWLSYRVVEPIGQTLFEISQYT 624
Query: 359 GWLTV 363
G + +
Sbjct: 625 GEIRI 629
Score = 46.4 bits (105), Expect = 0.006
Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 438 QLMSFVNVEVTLLDANDNNP-VFVPSNLYEF----SMKSNAKVGTVIGKVKAVDPDLGQN 492
+L S V+V + +LD NDN P V P + F + +A G ++ K+ A+DPD G N
Sbjct: 543 KLFSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHN 602
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
+ Y + T+ F+I+ TG + + S
Sbjct: 603 AWLSYRVVEPIGQTL---FEISQYTGEIRIIRS 632
Score = 44.8 bits (101), Expect = 0.018
Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 221 IDQDLGVGAT----LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ QDLG+ R L SG + + F +D G+L + +D ++ + +L +
Sbjct: 47 VAQDLGLNMADIEKRRLSLRSGANGRYFFVDQKTGALTVRDRIDRESLCGSSLSC-LLPL 105
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN-GFSVLQVMATDKDQ 335
+ + P + V+IE+LD+NDN P F D I I+E N G A D D
Sbjct: 106 ELG-IEKPFELFS--VDIEILDVNDNSPSFLSDNQIIQIIEIFANPGVRFPLDTAEDSDV 162
Query: 336 GENGEFTYQLDDPKGAFSIDPRS 358
G NG Y++ +P FS+ ++
Sbjct: 163 GINGINQYKI-NPNPFFSLSVKN 184
>UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 4697
Score = 107 bits (258), Expect = 2e-21
Identities = 129/502 (25%), Positives = 207/502 (41%), Gaps = 47/502 (9%)
Query: 390 VVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTL 449
V G D+ RI + Q + N PL+ V V E Y ++ + V V +TL
Sbjct: 1000 VGGNKNDAFRIDRTTGQ-IAVNKPLDYE--VLQSYVLNVRATCETYTPKIAAEVAVAITL 1056
Query: 450 LDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVK------------AVDPDLGQNGMVL 496
D NDN+PVF + SN ++ S TV+ K + AVD D G V
Sbjct: 1057 TDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKARRFTYYVIYEKALAVDADSESFGTVR 1116
Query: 497 YDL-QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
Y + +SN + PF ++ ++G + R V SL +
Sbjct: 1117 YSINSASSNPSSDLPFSLDASSGQMKTTRVIKYSDRAEYTVALVATDGGGKSTTTSLVIK 1176
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
+ N+P P F YEF V N +GT +G I A + Y + G
Sbjct: 1177 VFNI------NEP--PKFPQPKYEFSVPENKQVGTEIGAITATYADPNTLLKYSITRGNI 1228
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ F V + GVI++ L + + +A+ +N + V TV+ D+ND +
Sbjct: 1229 DDT-FCVNSK-GVISLAKALDSETKASFTLDAMVSHGTSNHTTVVQITVN--DINDNWPI 1284
Query: 676 LLKGAHSPII-FHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD--IA 731
+ P+ V+E+ A G + ++ T++ G G + + I QD+ A
Sbjct: 1285 M-----EPVYNVEVREDQAPGTELVKVVATDLD---GGVGGTITYTIIQTQDIGSSSLFA 1336
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+ A G I + LD E + + + V AE A I +V + + D ND+ P F +
Sbjct: 1337 VNASTGVITLVQKLDAEDINKHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSS 1396
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFI 849
Y + + + + ATDAD G+NA Y + G ++ +F ++ G+V +
Sbjct: 1397 QYLASVPYEFPVNFHVFQ---VIATDADSGSNAELTYAITGGNEDGIFKINSENGLVS-L 1452
Query: 850 GDSLDREKKIMYKLSLVARDTG 871
L KI +KLSL A D G
Sbjct: 1453 ARPLASSAKIKHKLSLKATDNG 1474
Score = 107 bits (257), Expect = 2e-21
Identities = 110/463 (23%), Positives = 195/463 (42%), Gaps = 32/463 (6%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ-NGMVLYDLQ 500
F+ ++VT DANDN P+F +YE S++ + GT + V A+D D + Y +
Sbjct: 2723 FLTIKVT--DANDNAPLF-SKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSID 2779
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F+I+ +TG ++ SP+ + + ++ R + V +++
Sbjct: 2780 KRGE----QYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRAEVMVTLVDIN 2835
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEE--G 617
P F PY + N IGT+V ++ D + N + +++ E+ G
Sbjct: 2836 -------DQAPFFPNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIYSLEDNNG 2888
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
++ SG++T + + R F+ + ++ TV V DE
Sbjct: 2889 GYVTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKP 2948
Query: 678 KGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K V E++ G A+ ++ T+ + Y NG N F++ + I G
Sbjct: 2949 KFVRQYYYASVSESTRTGVAVTRVEATDEDTGY-NGMMNY-FIVQGNEPYAFFIE-PRTG 3005
Query: 737 TIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
+ LD E + Y + V +++ + + V + I D+N +PP F +E
Sbjct: 3006 VVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHEAS 3065
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN-----TGVVKFIG 850
+ E+ +G + IKATD D + G+ + MF + E+ T ++ G
Sbjct: 3066 VREDVPLGYSVLT---IKATDIDTVDSFHRFLISSGDEENMFTITESESEKMTAIITVRG 3122
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
LDRE+K Y + +V DT G S E + I + D NDN P F
Sbjct: 3123 -KLDRERKSFYNMIVVVNDTSGQSDECIVKITVTDANDNGPHF 3164
Score = 102 bits (245), Expect = 7e-20
Identities = 133/477 (27%), Positives = 205/477 (42%), Gaps = 49/477 (10%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+++ + V+++DANDN P+F + Y S+ A VG + +VKA+D D G N V Y
Sbjct: 2294 INYCLIIVSVVDANDNYPLF-HIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTF 2352
Query: 500 QRTSNLTITSPFKINPNTGTVSV-AESPILEGRHALFVEASDQ-PANPS---ERRYSLAV 554
S+ F I TG V+V + G L V++S+ P S + R +
Sbjct: 2353 VEPSD-----KFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTL 2407
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLH 612
V I+VT + P F Y V N +GT++GQIR A QN+ + Y LH
Sbjct: 2408 VVIDVT------TVEPPMFERHLYNISVRENAAVGTTIGQIR---AVSQNNRPIMYQPLH 2458
Query: 613 ---GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN---ATVHV 666
+E + ++ S V + D N F AV + + +++ + V V
Sbjct: 2459 ENPNAKEEIGIEIDTGSIVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTV 2518
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
+DVND + IF ENS G I ++ ++ TG V + + +D
Sbjct: 2519 IDVNDHTPTFNMETYECRIF---ENSPVGTGIIRVHAEDLD------TGRVTYSLHPSRD 2569
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ GTI DRE+ Y +T IA ++ V I + D ND PP
Sbjct: 2570 YQKFTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVF-VKIDVLDANDQPP 2628
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT-- 843
F + + E++ IG+ + +I +D T+ F + G K F V T
Sbjct: 2629 SFPDKNLQASVREDAPIGSSV-YKAVILDSDMVFDTSMHF-FISGGNEKHKFRVVTVTQQ 2686
Query: 844 ----GVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
G+V+ IG LD E + +KL L D G S L I + D NDN P F+++
Sbjct: 2687 SSFYGLVEVIG-RLDYETQREFKLRLTISD-GKTSDFGFLTIKVTDANDNAPLFSKL 2741
Score = 99.5 bits (237), Expect = 6e-19
Identities = 119/466 (25%), Positives = 200/466 (42%), Gaps = 34/466 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V VT++D ND+ P F YE + N+ VGT I +V A D D G+ V Y
Sbjct: 2508 LFSTCFVNVTVIDVNDHTPTF-NMETYECRIFENSPVGTGIIRVHAEDLDTGR---VTYS 2563
Query: 499 LQRTSNLTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
L + + F I+ GT+ +V E R++L A+D + P + + +
Sbjct: 2564 LHPSRDY---QKFTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKIDV 2620
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS-YDLLHGYE 615
++ ++P P F + V + IG+SV + + D+ D S + + G
Sbjct: 2621 LDAN-----DQP--PSFPDKNLQASVREDAPIGSSVYKAVILDSDMVFDTSMHFFISGGN 2673
Query: 616 EGVPF---AVEERSGVITVVDDLSRYN-RPMYDFEAVALQENANLSIVTNATVHVVDVND 671
E F V ++S +V+ + R + +F+ + S T+ V D ND
Sbjct: 2674 EKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTISDGKTSDFGFLTIKVTDAND 2733
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ K + + +E+ AG ++ + ++ S + + I + + I+
Sbjct: 2734 NAPLFSKLVYEVSLR--EESPAGTSVVTVSAIDIDSPPVQEA--ITYSIDKRGEQYFRIS 2789
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ PLDREK Y TV A K G +V + + D ND P F +
Sbjct: 2790 SSTGEITCGASPLDREKLLYYFFTVYASDGKN----QGRAEVMVTLVDINDQAPFFPNPP 2845
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y + EN IGT + + I D + G N +Y+L +D ++G+V I
Sbjct: 2846 YYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIYSLEDNNGGYVTIDSSSGLVTSI-K 2904
Query: 852 SLDRE--KKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+DRE ++ +K+++ A D G LS L + DEND+KP+F
Sbjct: 2905 MVDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKPKF 2950
Score = 91.5 bits (217), Expect = 2e-16
Identities = 114/466 (24%), Positives = 199/466 (42%), Gaps = 38/466 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQR 501
V VTL+D ND P F P+ Y ++ N +GT + ++A+D P+ G N ++Y L+
Sbjct: 2827 VMVTLVDINDQAPFF-PNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIYSLED 2885
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ +T T V + E + V A+DQ P+ ++ V E
Sbjct: 2886 NNGGYVTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQ-GQPALSGTTVLQVFFEDEN 2944
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGVP 619
K P F+ Y V + G +V ++ D + ++Y ++ G E
Sbjct: 2945 DHK------PKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQG-NEPYA 2997
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
F +E R+GV+ V L ++ Y+ + + N V++ D+ +
Sbjct: 2998 FFIEPRTGVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHPPRF 3057
Query: 680 AHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIA-----NQQDVTDDIAIA 733
A V+E+ G ++ I T++ ++ RFLI+ N +T+ +
Sbjct: 3058 AQKVHEASVREDVPLGYSVLTIKATDIDTV----DSFHRFLISSGDEENMFTITESESEK 3113
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
I + LDRE++ Y M V+ G S I ++T+ D NDN P F+ + +
Sbjct: 3114 MTAIITVRGKLDRERKSFYNMIVVVNDTSGQ-SDECIVKITV--TDANDNGPHFQPSYFS 3170
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFG-EGKEMFDVDENTGVVK---- 847
GF+ EN I +E + I ATD D +N F +TL + F + ++T
Sbjct: 3171 GFVREN--IDSE-QFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQV 3227
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
F + DRE YKL + A D+G + + + + + D N+++P
Sbjct: 3228 FAYGTFDRELTPFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEP 3273
Score = 90.2 bits (214), Expect = 4e-16
Identities = 94/401 (23%), Positives = 175/401 (43%), Gaps = 27/401 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V++T+ D NDN P+ P +Y ++ + GT + KV A D D G G + Y + +T +
Sbjct: 1271 VQITVNDINDNWPIMEP--VYNVEVREDQAPGTELVKVVATDLDGGVGGTITYTIIQTQD 1328
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ +S F +N +TG +++ + E +H L+V+A D P +Y+ A+ + V G
Sbjct: 1329 IGSSSLFAVNASTGVITLVQKLDAEDINKHVLYVKAEDGGPTP---KYA-AITKVVVLVG 1384
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYEEGVPF 620
+ P F + Y V + V Q+ DA + +++Y + G E+G+ F
Sbjct: 1385 DVNDHA--PRFSSSQYLASVPYEFPVNFHVFQVIATDADSGSNAELTYAITGGNEDGI-F 1441
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+ +G++++ L+ + + A I T+ + V + D +L K
Sbjct: 1442 KINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRRIGTSTIIVFVILAD---LLPKFP 1498
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT 740
SP+I +VKE G++ M+S + R L N + +++ G +
Sbjct: 1499 VSPLIVNVKEGVLPG--GRVTTVKMTS---SRLMTYRILEGNDEGYFRMDSLS--GDLLA 1551
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
K LD E + M + + G A + + + +ED ND PVF G +M
Sbjct: 1552 LKELDYEDVRTFTMRIKGQDTDG---NADVVTLVVNLEDVNDCSPVFA-GEVGGEVMLRV 1607
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
+ + ++K D+ + L EG+ +F +D+
Sbjct: 1608 EEPFLVAGVPVVKLDVYDKDAGDRLTFELSDEGERIFTIDD 1648
Score = 87.4 bits (207), Expect = 3e-15
Identities = 98/412 (23%), Positives = 179/412 (43%), Gaps = 33/412 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ V + L + NDN P F S L+ ++ + VGT I +V A D D ++ + + T
Sbjct: 1982 IPVIIHLKNINDNYPRFTKS-LFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPG-ELT 2039
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEVT 560
++ T F I+P+TG +S A S E L V+ D+ +P+ + + + V
Sbjct: 2040 YSIDNTDMFAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVN 2099
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+ P F + Y F + +G + + D + + ++Y + G + P+
Sbjct: 2100 DNS-------PVFAQSNYAFQISETAEVGNELAFVTATDR-DGDPITY-TIEG--DSGPY 2148
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
++ SG+IT+ + + N Y+F+ A + + T+ + ++D N+ +
Sbjct: 2149 IIDPSSGIITLSRE-APVNVWEYNFKVKA--TDGIFTATTDVLLDIIDQNNHKPQFTNCG 2205
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRF-LIANQQDVTDDIAIAEDGTI 738
S VKE + GQ+ ++ G G V + L+ D + D G I
Sbjct: 2206 ESSRT--VKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELVIGFTDFSID---NTTGVI 2260
Query: 739 FTQKPLDREKRDVYRMTVIAE----FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
T+ PLDRE+ + V A+ + + + + D NDN P+F Y
Sbjct: 2261 KTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVS 2320
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
+ + + +G + +KA D D G+NA YT F E + F +++ TG+V
Sbjct: 2321 SVYQKAPVGHSLVR---VKAIDLDTGSNAKVEYT-FVEPSDKFAIEKTTGIV 2368
Score = 86.2 bits (204), Expect = 6e-15
Identities = 116/478 (24%), Positives = 196/478 (41%), Gaps = 41/478 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKS---NAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+V + ++D N++ P F ++K N G V+ +V+A D D G NG V Y+L
Sbjct: 2186 DVLLDIIDQNNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYEL- 2244
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSE--RRYSLAVVT 556
+ + F I+ TG + E + + V A D +E R + ++
Sbjct: 2245 ----VIGFTDFSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLII 2300
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ V + P F Y V +G S+ +++ D ++ + E
Sbjct: 2301 VSVVDA----NDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTF-VEP 2355
Query: 617 GVPFAVEERSGVITVVDDLSRY----NRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
FA+E+ +G++TV DLS + + V + + T+ V+DV
Sbjct: 2356 SDKFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV 2415
Query: 673 RGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + H I V+EN+A G IGQI ++ N + + + ++I
Sbjct: 2416 EPPMFE-RHLYNI-SVRENAAVGTTIGQI-----RAVSQNNRPIMYQPLHENPNAKEEIG 2468
Query: 732 IAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ---VTIYIEDENDNPPVF 787
I D G+I T LD E + Y + +A S ++ V + + D ND+ P F
Sbjct: 2469 IEIDTGSIVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTF 2528
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
TYE I ENS +GT I + A D D G ++ + F +D G ++
Sbjct: 2529 NMETYECRIFENSPVGTGIIR---VHAEDLDTGRVTYSLHP--SRDYQKFTIDTQRGTIR 2583
Query: 848 FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
DRE++ Y L+ +A D G S++ + I + D ND P F + VR
Sbjct: 2584 -NAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVR 2640
Score = 86.2 bits (204), Expect = 6e-15
Identities = 67/217 (30%), Positives = 103/217 (47%), Gaps = 22/217 (10%)
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD---SGLNGQIRY--EFN 971
T++++ + F + LF EN IGT + + A+D D +G N +I Y E N
Sbjct: 2830 TLVDINDQAPFFPNPPYYAALF---ENRAIGTNVTVMQAIDNDDPNAGGNTKIIYSLEDN 2886
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNI 1029
+ Y+ S +K +V R E F++ + A D G L+
Sbjct: 2887 NGGYVTIDSSSGLVTSIK------------MVDREALQEDSFKVTVRATDQGQPALSGTT 2934
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
++VF +D NDH P F + +Y +V E+ T + +V+ATD D G N + YFI +
Sbjct: 2935 VLQVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQGNE 2994
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F I P TGV+ V+G LD E++ Y L V+ D G
Sbjct: 2995 PYAFFIEPRTGVVRVSGILDFESKKSYELIVMVSDMG 3031
Score = 81.0 bits (191), Expect = 2e-13
Identities = 87/353 (24%), Positives = 154/353 (43%), Gaps = 22/353 (6%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISAL-DGGNLNDNISVRVFVKDVNDHFPVFKKTWY 1050
F +N + G + +A++L E++ + A+ G N V++ V D+ND++P+ + Y
Sbjct: 1232 FCVNSK-GVISLAKALDSETKASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPV-Y 1289
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSD--TDLPFEISPLTGVLSVNGE 1107
N V E Q L KV ATD D G +TY IQ D + F ++ TGV+++ +
Sbjct: 1290 NVEVREDQAPGTELVKVVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLVQK 1349
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LD E +K++L V A D G DVND++P+F + L P
Sbjct: 1350 LDAEDINKHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLA--SVPYEFP 1407
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP---QRKNQ 1224
++ H F+ + A NA + + + I + NGL+ + P K +
Sbjct: 1408 VNFHVFQVI----ATDADSGSNAELTYAITGGNEDGIFKINSENGLVSLARPLASSAKIK 1463
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFISRYYELEIEENVNAPVELVSLNLTE 1283
L L + + + + + V ++D P F + ++E V + ++ +T
Sbjct: 1464 HKLSLKATDNGVPRRIGTSTIIVFVILADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMT- 1522
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ M Y IL ND F +D +G L ++ D E T+ + ++ +
Sbjct: 1523 --SSRLMTYRILEGNDEGY---FRMDSLSGDLLALKELDYEDVRTFTMRIKGQ 1570
Score = 79.4 bits (187), Expect = 7e-13
Identities = 75/304 (24%), Positives = 121/304 (39%), Gaps = 23/304 (7%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-EKAFIFLIAPIGPSLT 129
G N + +Y ++T+ VNDN P+F + Y + E G E AF+ G +T
Sbjct: 2081 GGSPNIMQSYANITLL--PVNDNSPVFAQSNYAFQISETAEVGNELAFVTATDRDGDPIT 2138
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
+ G I P + Y+ DG F + +L ++D
Sbjct: 2139 YTIEGDSGPYIIDPSSGIITLSREAPVNVWEYNFKVKATDGIFTATTD-----VLLDIID 2193
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEP-------IHAIDQDLGVGATLRYELISGNDRK 242
+ +F R KEI P + A D+D G+ + YEL+ G
Sbjct: 2194 QNNHKPQF--TNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELVIGFTD- 2250
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL--KTAQARVEIELLDLN 300
FS+D+ G ++ LD E + V N L + + ++D N
Sbjct: 2251 -FSIDNTTG--VIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDAN 2307
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
DN P F + Y S+ + P G S+++V A D D G N + Y +P F+I+ +G
Sbjct: 2308 DNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDKFAIEKTTGI 2367
Query: 361 LTVR 364
+TV+
Sbjct: 2368 VTVK 2371
Score = 73.7 bits (173), Expect = 3e-11
Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 15/193 (7%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVN--GSLFLE-KELDLDAEHNLQANTF 272
E HA D+D G Y +ISGN++ F ++N FL+ DL + NT
Sbjct: 144 ENCHAEDRD--TGGISSYTIISGNEKGYFKTSTINVGEERFLQILTTDLPITRDT-TNTI 200
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
L V+A +P +T ++ I + + N+N P+FE + Y ++E V +V A D
Sbjct: 201 KLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKD 260
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA-------KE 385
DQG +G Y L F+++P +G + + LD + SS ++ V A +E
Sbjct: 261 TDQGMSGSVYYYLSPLSSYFTVNPITGVVILVG--TLDYQKQSSYQLTVMATDRGSPRRE 318
Query: 386 TNPSVVGTFADSQ 398
V+ T DSQ
Sbjct: 319 AATKVILTIKDSQ 331
Score = 73.7 bits (173), Expect = 3e-11
Identities = 60/185 (32%), Positives = 87/185 (47%), Gaps = 15/185 (8%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT ++K+ A DLD G+ G I Y I S L F +N G + + +
Sbjct: 1300 GTELVKVVATDLDGGVGGTITYTIIQTQDIGSSSL----------FAVNASTGVITLVQK 1349
Query: 1007 LPPE--SEFRLNISALDGGNLNDNISVR---VFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
L E ++ L + A DGG ++ V V DVNDH P F + Y +V
Sbjct: 1350 LDAEDINKHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPVN 1409
Query: 1062 RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVV 1121
+ +V ATDAD G NA LTY I + D F+I+ G++S+ L + K+ L++
Sbjct: 1410 FHVFQVIATDADSGSNAELTYAITGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLK 1469
Query: 1122 ARDNG 1126
A DNG
Sbjct: 1470 ATDNG 1474
Score = 72.9 bits (171), Expect = 6e-11
Identities = 71/284 (25%), Positives = 125/284 (44%), Gaps = 20/284 (7%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A + YE+ SGN R F + ++ G + ++ + + N + L V AS+L
Sbjct: 1925 ALIAYEITSGNVRNSFKIGTLTGEIRHNNFMN----YEIHENVYNLTVTASELIPRGHQT 1980
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-----GEFTY 343
+ V I L ++NDN P F + ++ E++P G S+LQV ATD D ++ GE TY
Sbjct: 1981 EIPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTY 2040
Query: 344 QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKW 403
+D+ F+I P +G ++ + + L +KV K +P+++ ++A+ +
Sbjct: 2041 SIDN-TDMFAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLL--- 2096
Query: 404 RRQPLETNAPL-EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFV-- 460
P+ N+P+ ++ Y F + N E +T D+ P +
Sbjct: 2097 ---PVNDNSPVFAQSNYAFQISETAEVGN-ELAFVTATDRDGDPITYTIEGDSGPYIIDP 2152
Query: 461 PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
S + S ++ V KVKA D VL D+ +N
Sbjct: 2153 SSGIITLSREAPVNVWEYNFKVKATDGIFTATTDVLLDIIDQNN 2196
Score = 72.5 bits (170), Expect = 8e-11
Identities = 70/284 (24%), Positives = 124/284 (43%), Gaps = 26/284 (9%)
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
+PF+++ SG + + +R Y VA + S T+ + V ++N+
Sbjct: 1130 LPFSLDASSGQMKTTRVIKYSDRAEYTVALVAT-DGGGKSTTTSLVIKVFNINEPP---- 1184
Query: 678 KGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
K F V EN G IG I T Y + +++ I + ++ D + G
Sbjct: 1185 KFPQPKYEFSVPENKQVGTEIGAITAT-----YADPNTLLKYSIT-RGNIDDTFCVNSKG 1238
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I K LD E + + T+ A + G + + Q+T+ D NDN P+ E Y +
Sbjct: 1239 VISLAKALDSETKASF--TLDAMVSHGTSNHTTVVQITV--NDINDNWPIME-PVYNVEV 1293
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDENTGVVKFIG-- 850
E+ GTE+ + ATD D G YT+ +F V+ +TGV+ +
Sbjct: 1294 REDQAPGTELVK---VVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLVQKL 1350
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
D+ D K ++Y + T ++ ++++++GD ND+ P F+
Sbjct: 1351 DAEDINKHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFS 1394
Score = 72.1 bits (169), Expect = 1e-10
Identities = 87/301 (28%), Positives = 122/301 (40%), Gaps = 42/301 (13%)
Query: 115 KAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
K F P P +VP + +I A + PN+ + YSI GN D F +
Sbjct: 1176 KVFNINEPPKFPQPKYEFSVPENKQVGTEIGAITATYAD-PNTLLKYSITRGNIDDTFCV 1234
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMAS-GKRIHKEIL----------FP--EPIH-- 219
S K V+ L K LD + F L M S G H ++ +P EP++
Sbjct: 1235 NS--KGVISLAKALDSET-KASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPVYNV 1291
Query: 220 ----------------AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL-FLEKELDLD 262
A D D GVG T+ Y +I D SL +VN S + LD
Sbjct: 1292 EVREDQAPGTELVKVVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLVQKLD 1351
Query: 263 AEHNLQANTFVLQVQASQLN-NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN 321
AE N VL V+A P A +V + + D+ND+ P F Y S+ P
Sbjct: 1352 AE---DINKHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPV 1408
Query: 322 GFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
F V QV+ATD D G N E TY + + G F I+ +G +++ + L +
Sbjct: 1409 NFHVFQVIATDADSGSNAELTYAITGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSL 1468
Query: 380 K 380
K
Sbjct: 1469 K 1469
Score = 68.1 bits (159), Expect = 2e-09
Identities = 51/167 (30%), Positives = 85/167 (50%), Gaps = 10/167 (5%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D + G + Y L N+ ++DS +G + K +D +A LQ ++F + V+A+
Sbjct: 2870 DPNAGGNTKIIYSL-EDNNGGYVTIDSSSGLVTSIKMVDREA---LQEDSFKVTVRATDQ 2925
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
P + +++ D ND+ P+F +Y S+ E+ G +V +V ATD+D G NG
Sbjct: 2926 GQPALSGTTVLQVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMM 2985
Query: 342 TY---QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
Y Q ++P AF I+PR+G VR +LD E+ S + V +
Sbjct: 2986 NYFIVQGNEPY-AFFIEPRTG--VVRVSGILDFESKKSYELIVMVSD 3029
Score = 67.7 bits (158), Expect = 2e-09
Identities = 107/478 (22%), Positives = 184/478 (38%), Gaps = 48/478 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ PIG+++ K LD D + + + + ++ + Y ++
Sbjct: 2639 VREDAPIGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVE---- 2694
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
VI + EF+L ++ DG +D + + V D ND+ P+F K Y ++ E
Sbjct: 2695 -VIGRLDYETQREFKLRLTISDG-KTSDFGFLTIKVTDANDNAPLFSKLVYEVSLREESP 2752
Query: 1060 TRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTGVLSVNGE-LDRETEDKYI 1117
+ V A D D +TY I F IS TG ++ LDRE Y
Sbjct: 2753 AGTSVVTVSAIDIDSPPVQEAITYSIDKRGEQY-FRISSSTGEITCGASPLDREKLLYYF 2811
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP-----KFYA--FDELLEWKHPEADELSN 1170
TV A D D+ND +P +YA F+ + + +
Sbjct: 2812 FTVYASDG----KNQGRAEVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAID 2867
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNLGL 1229
++ + ++E+N T+ T + + L S + G
Sbjct: 2868 NDDPNAGGNTKIIYSLEDNNGGYVTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQ 2927
Query: 1230 PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFK 1289
P+LS T +L V D D KP F+ +YY + E+ V + + T+ +
Sbjct: 2928 PALSGTTVLQVFFEDENDH-----KPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYN 2982
Query: 1290 --MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
M Y+I+ N+ F I+PR G + + D E K +YE+IV +P +
Sbjct: 2983 GMMNYFIVQGNEP---YAFFIEPRTGVVRVSGILDFESKKSYELIVMVS----DMGMPQL 3035
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
+ A+++ V V I D N + P+F + ++ P GY V+ +K
Sbjct: 3036 L---ADNL--------AYVFVNITDDNTHPPRF--AQKVHEASVREDVPLGYSVLTIK 3080
Score = 66.9 bits (156), Expect = 4e-09
Identities = 88/339 (25%), Positives = 147/339 (43%), Gaps = 38/339 (11%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFL--DTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT 133
+I+A ++V + + DVNDN P+FL P VTV+ TP F L
Sbjct: 1045 KIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKARRFTYYVIYEKALA 1104
Query: 134 VPRGLTIFKDIRAFDRDKPNTPNSDVHYSI--VSGNDDGHFALESSHKPVLLLRKVLDYD 191
V F +R + P+SD+ +S+ SG ++ S + + V D
Sbjct: 1105 VDADSESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTRVIKYSDRAEYTVALVAT-D 1163
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIH--AIDQDLGVG-------AT-------LRYEL 235
G K ++ I++ FP+P + ++ ++ VG AT L+Y +
Sbjct: 1164 GGGKSTTTSLVIKVFNINEPPKFPQPKYEFSVPENKQVGTEIGAITATYADPNTLLKYSI 1223
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
GN F ++S G + L K LD + + + F L S + T V+I
Sbjct: 1224 TRGNIDDTFCVNS-KGVISLAKALDSETKAS-----FTLDAMVSHGTSNHTTV---VQIT 1274
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY---QLDD--PKG 350
+ D+NDN P E YN+ + E+ G +++V+ATD D G G TY Q D
Sbjct: 1275 VNDINDNWPIME-PVYNVEVREDQAPGTELVKVVATDLDGGVGGTITYTIIQTQDIGSSS 1333
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
F+++ +G +T+ + LD E + + V A++ P+
Sbjct: 1334 LFAVNASTGVITLVQK--LDAEDINKHVLYVKAEDGGPT 1370
Score = 64.9 bits (151), Expect = 2e-08
Identities = 146/675 (21%), Positives = 274/675 (40%), Gaps = 82/675 (12%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS-QLNNPLKT 287
A + Y ++ GN F +D G + + K LD + LQ+ +VL V+A+ + P
Sbjct: 993 AAITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEV---LQS--YVLNVRATCETYTPKIA 1047
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
A+ V I L D+NDN P F + + N + V N ++ Q + + FTY +
Sbjct: 1048 AEVAVAITLTDVNDNSPVFLL-YSNPTTV--TVNSYTPEQTVVF-----KARRFTYYVIY 1099
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQP 407
K A ++D D E+ ++R + + +NPS F+
Sbjct: 1100 EK-ALAVD-------------ADSESFGTVRYSINSASSNPSSDLPFS------------ 1133
Query: 408 LETNAPLEKTTYV--FPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
L+ ++ KTT V + D+ + + ++ + + + N+ P P Y
Sbjct: 1134 LDASSGQMKTTRVIKYSDRAEYTVALVATDGGGKSTTTSLVIKVFNINE--PPKFPQPKY 1191
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
EFS+ N +VGT IG + A D N ++ Y + R + I F +N + G +S+A++
Sbjct: 1192 EFSVPENKQVGTEIGAITATYAD--PNTLLKYSITRGN---IDDTFCVN-SKGVISLAKA 1245
Query: 526 PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + + ++A ++ + ++ +T+ N P M Y V +
Sbjct: 1246 LDSETKASFTLDA--MVSHGTSNHTTVVQITV---NDINDNWP----IMEPVYNVEVRED 1296
Query: 586 VGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGVP--FAVEERSGVITVVD--DLSRYN 639
GT + ++ D ++Y ++ + G FAV +GVIT+V D N
Sbjct: 1297 QAPGTELVKVVATDLDGGVGGTITYTIIQTQDIGSSSLFAVNASTGVITLVQKLDAEDIN 1356
Query: 640 RPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
+ + +A + +T V V DVND + + + E + Q
Sbjct: 1357 KHVLYVKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPY--EFPVNFHVFQ 1414
Query: 700 IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ T+ S G+ + +D I +E+G + +PL + +++++ A
Sbjct: 1415 VIATDADS--GSNAELTYAITGGNEDGIFKIN-SENGLVSLARPLASSAKIKHKLSLKAT 1471
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
N GV G + +++ D P F + + E G + +K T
Sbjct: 1472 DN-GVPRRIGTSTIIVFV-ILADLLPKFPVSPLIVNVKEGVLPGGRV---TTVKMT---- 1522
Query: 820 GTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
++ L Y + G + F +D +G + + + LD E + + + +DT G +
Sbjct: 1523 -SSRLMTYRILEGNDEGYFRMDSLSGDLLALKE-LDYEDVRTFTMRIKGQDTDGNADVVT 1580
Query: 879 LIIMIGDENDNKPEF 893
L++ + D ND P F
Sbjct: 1581 LVVNLEDVNDCSPVF 1595
Score = 64.5 bits (150), Expect = 2e-08
Identities = 108/446 (24%), Positives = 180/446 (40%), Gaps = 44/446 (9%)
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQ-NGMVLYDLQRTSNLTITSPFKINPNTGTVSVA 523
Y ++ S+ T I V A D D + N VL+ ++ + + F+I+ +TGT++
Sbjct: 863 YWATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTGTITST 922
Query: 524 ESPILEGRHALFVEASDQPANPSERRYSLAV-VTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
+ L V+A+D + P E + S+ V V +T K F A Y +
Sbjct: 923 NLLAANNEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVK--------FAEANYAKTI 974
Query: 583 GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
++ IG SV Q+ A ++Y ++ G + F ++ +G I V L
Sbjct: 975 QESLVIGNSVLQV---TATGPAAITYSIVGGNKNDA-FRIDRTTGQIAVNKPLDYEVLQS 1030
Query: 643 YDFEAVALQENANLSIVTNATVHV--VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
Y A E I V + DVND V L ++ + + +
Sbjct: 1031 YVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKA 1090
Query: 701 FHTNMSSIY---------GNGTGNVRFLI-ANQQDVTDDIAI---AEDGTIFTQKPLDRE 747
IY G VR+ I + + + D+ A G + T + +
Sbjct: 1091 RRFTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTRVIKYS 1150
Query: 748 KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
R Y + ++A G + + I + + N+ PP F YE + EN ++GTEI
Sbjct: 1151 DRAEYTVALVATDGGGKSTTTSL---VIKVFNINE-PPKFPQPKYEFSVPENKQVGTEI- 1205
Query: 808 MDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
I AT AD N L Y++ G + F V+ + GV+ + +LD E K + L
Sbjct: 1206 --GAITATYAD--PNTLLKYSITRGNIDDTFCVN-SKGVIS-LAKALDSETKASFTLD-- 1257
Query: 867 ARDTGGLSSEAELI-IMIGDENDNKP 891
A + G S+ ++ I + D NDN P
Sbjct: 1258 AMVSHGTSNHTTVVQITVNDINDNWP 1283
Score = 64.5 bits (150), Expect = 2e-08
Identities = 42/149 (28%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
N ++ ++ GS+ +LD ++ +N + FV ++ + L + V + ++D
Sbjct: 2462 NAKEEIGIEIDTGSIVTSSKLDYESVNNYELQ-FVAVETSTDKSETLLFSTCFVNVTVID 2520
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDP 356
+ND+ P F ++ Y I EN P G +++V A D D G TY L + F+ID
Sbjct: 2521 VNDHTPTFNMETYECRIFENSPVGTGIIRVHAEDLD---TGRVTYSLHPSRDYQKFTIDT 2577
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ G T+RN V DRE S + A +
Sbjct: 2578 QRG--TIRNAVVFDREEESRYSLTAIATD 2604
Score = 64.1 bits (149), Expect = 3e-08
Identities = 93/420 (22%), Positives = 175/420 (41%), Gaps = 39/420 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ +++ + N+N P F Y + ++ + + +V A D D G +G V Y L
Sbjct: 220 IHISVENRNENTPKFEKEE-YTAMVMEETQLNSPVARVHAKDTDQGMSGSVYYYLS---- 274
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
++S F +NP TG V + + + + + L V A+D+ +P + ++TI+ ++
Sbjct: 275 -PLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDR-GSPRREAATKVILTIKDSQF 332
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF------EQNDV---SYDLLH- 612
+ P AP V + + T+V + + F ND + LL+
Sbjct: 333 SPPADSADPGANTAP----VFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYS 388
Query: 613 --GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVD 668
G E G+ FA++ S V+T+ L P V + + ++ +A V++ D
Sbjct: 389 LSGPEAGL-FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKD 447
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
V++ + + + + I VKE++A IF + G + + + + V
Sbjct: 448 VDENQNLPVFDPKAQAI-SVKEDTALGT--SIFTAKATDEDSGPDGELEYSMVAGEGVGY 504
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I G + T DR+ V + VIA +KG + + I +E +D P F
Sbjct: 505 VILNETTGVVTTAAMFDRKTNPVVEV-VIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFT 563
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVK 847
Y +++ S T + A A + N Y L G ++F V+ +TGV++
Sbjct: 564 QPAYSATVLDGSPENT------FVVALHATDYENTQIEYRLVNVGVNDLFQVERSTGVIR 617
Score = 63.3 bits (147), Expect = 5e-08
Identities = 44/154 (28%), Positives = 77/154 (50%), Gaps = 8/154 (5%)
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T P+ R+ + ++ V A + G + Q+ I +E+ N+N P FE Y +ME
Sbjct: 188 TDLPITRDTTNTIKLVVEAR-DSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMVMEE 246
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+++ + + + A D D+G + Y L F V+ TGVV +G +LD +K+
Sbjct: 247 TQLNSPVAR---VHAKDTDQGMSGSVYYYL-SPLSSYFTVNPITGVVILVG-TLDYQKQS 301
Query: 860 MYKLSLVARDTGGLSSEA--ELIIMIGDENDNKP 891
Y+L+++A D G EA ++I+ I D + P
Sbjct: 302 SYQLTVMATDRGSPRREAATKVILTIKDSQFSPP 335
Score = 61.3 bits (142), Expect = 2e-07
Identities = 79/336 (23%), Positives = 136/336 (40%), Gaps = 33/336 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF------------- 119
G NQ A + VT+ D+ND P F + PY+ + E G +
Sbjct: 2819 GKNQGRAEVMVTLV--DINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGN 2876
Query: 120 --LIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESS 177
+I + + +T+ + I+ DR+ + V V D G AL +
Sbjct: 2877 TKIIYSLEDNNGGYVTIDSSSGLVTSIKMVDREALQEDSFKV---TVRATDQGQPALSGT 2933
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS 237
VL + + D K + AS + + + A D+D G + Y ++
Sbjct: 2934 --TVLQVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQ 2991
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
GN+ F ++ G + + LD +++ + + V + QL L A V + +
Sbjct: 2992 GNEPYAFFIEPRTGVVRVSGILDFESKKSYELIVMVSDMGMPQL---LADNLAYVFVNIT 3048
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN-GEFTYQLDDPKGAFSI-- 354
D N + P F + S+ E++P G+SVL + ATD D ++ F D + F+I
Sbjct: 3049 DDNTHPPRFAQKVHEASVREDVPLGYSVLTIKATDIDTVDSFHRFLISSGDEENMFTITE 3108
Query: 355 ---DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
+ + +TVR + LDRE S M V +T+
Sbjct: 3109 SESEKMTAIITVRGK--LDRERKSFYNMIVVVNDTS 3142
Score = 60.9 bits (141), Expect = 3e-07
Identities = 34/115 (29%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 1014 RLNISALDGGNLNDNIS--VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+L + A D G+ ++ + + V++ N++ P F+K Y V E + +V A D
Sbjct: 201 KLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKD 260
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D G + ++ Y++ P + F ++P+TGV+ + G LD + + Y LTV+A D G
Sbjct: 261 TDQGMSGSVYYYLSPLSSY--FTVNPITGVVILVGTLDYQKQSSYQLTVMATDRG 313
Score = 60.5 bits (140), Expect = 3e-07
Identities = 90/410 (21%), Positives = 162/410 (39%), Gaps = 36/410 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P+GT II+++A DLD+ G++ Y + P ++ +R + N V
Sbjct: 2539 ENSPVGTGIIRVHAEDLDT---GRVTYSLH-----PSRDYQKFTIDTQRGTIRNA----V 2586
Query: 1002 IVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ R ES + L A D G+ + + V++ V D ND P F +V E
Sbjct: 2587 VFDRE--EESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAP 2644
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT------GVLSVNGELDRETE 1113
+ K D+D + ++ +FI + F + +T G++ V G LD ET+
Sbjct: 2645 IGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQ 2704
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPEADELSNH 1171
++ L + D D NDN+P F ++ L + P +
Sbjct: 2705 REFKLRLTISDG----KTSDFGFLTIKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTV 2760
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPS 1231
+ + PV +A G ++ ++ + + L L
Sbjct: 2761 SAIDIDSPPVQEAITYSIDKRGEQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGK 2820
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYE-LEIEENVNAPVELVSLNLTEHYENFKM 1290
A +MVT+ D+ D+ P + + +E I NV ++ + + N K+
Sbjct: 2821 NQGRAEVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTV-MQAIDNDDPNAGGNTKI 2879
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREV--KDTYEVIVRAERQ 1338
Y + + N + ID +G + ++ DRE +D+++V VRA Q
Sbjct: 2880 IYSLEDNNGGYV----TIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQ 2925
Score = 59.7 bits (138), Expect = 6e-07
Identities = 99/388 (25%), Positives = 157/388 (40%), Gaps = 44/388 (11%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN-----ANLTYF 1083
I V + +K++ND++P F K+ + V E + +V ATD D ++ LTY
Sbjct: 1982 IPVIIHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYS 2041
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
I +TD+ F ISP TGV+S LD E +L V D G
Sbjct: 2042 I--DNTDM-FAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKG-GSPNIMQSYANITLLP 2097
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
VNDNSP F + ++ E E+ N + AT + PI T+ +
Sbjct: 2098 VNDNSPVFAQSN--YAFQISETAEVGNE-------LAFVTATDRDGDPITYTIEG--DSG 2146
Query: 1204 TDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSD-KPVFI---- 1258
I +G+I S N ++ I T + D ++ ++ KP F
Sbjct: 2147 PYIIDPSSGIITLSREAPVNVWEYNFKVKATDGIFTATTDVLLDIIDQNNHKPQFTNCGE 2206
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYL 1317
S EI EN+ + L+ + T+ Y L TD F ID G +
Sbjct: 2207 SSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELVIGFTD----FSIDNTTGVIKT 2262
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
DRE ++VRA+ + R + L Y + ++V + D NDN
Sbjct: 2263 RYPLDRERTSKQYIVVRAKDGGHRR-----------NELFRNINYCL-IIVSVVDANDNY 2310
Query: 1378 PKFTNGNRPLVTAIPTTAPFGYQVMQLK 1405
P F + +R V+++ AP G+ ++++K
Sbjct: 2311 PLF-HIHR-YVSSVYQKAPVGHSLVRVK 2336
Score = 59.3 bits (137), Expect = 8e-07
Identities = 94/413 (22%), Positives = 160/413 (38%), Gaps = 48/413 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGL-NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ + P T I+ + A DLD N Q+ ++F S+ AD+ R F I+
Sbjct: 867 VSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSD---------ADSSGQNR-FQIDSST 916
Query: 999 GHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + L +E++L + A D G+ + +SV V V F + Y ++E
Sbjct: 917 GTITSTNLLAANNEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQE 976
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ + +V AT A +TY I + + F I TG ++VN LD E Y
Sbjct: 977 SLVIGNSVLQVTATGP-----AAITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSY 1031
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
+L V A DVNDNSP F L + +P ++++ E
Sbjct: 1032 VLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVF------LLYSNPTTVTVNSYTPEQT 1085
Query: 1177 MMIPVYKAT---IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP--------QRKNQQ 1225
++ + T I E A ++ F I + + LP Q K +
Sbjct: 1086 VVFKARRFTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTR 1145
Query: 1226 NLGLPSLSSTAILMV---------TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL 1276
+ + + +V T + V +++ P F YE + EN E+
Sbjct: 1146 VIKYSDRAEYTVALVATDGGGKSTTTSLVIKVFNINEPPKFPQPKYEFSVPENKQVGTEI 1205
Query: 1277 VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
++ T N ++Y I N D TF ++ + G + L ++ D E K ++
Sbjct: 1206 GAITATYADPNTLLKYSITRGNIDD---TFCVNSK-GVISLAKALDSETKASF 1254
Score = 57.2 bits (132), Expect = 3e-06
Identities = 122/547 (22%), Positives = 219/547 (40%), Gaps = 76/547 (13%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ V V + D ND+ P F S+ Y S+ V + +V A D D G N + Y +
Sbjct: 1375 AITKVVVLVGDVNDHAPRF-SSSQYLASVPYEFPVNFHVFQVIATDADSGSNAELTYAIT 1433
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEG---RHALFVEASDQPANPSERRYSLAVVTI 557
+ I FKIN G VS+A P+ +H L ++A+D N RR + + +
Sbjct: 1434 GGNEDGI---FKINSENGLVSLAR-PLASSAKIKHKLSLKATD---NGVPRRIGTSTIIV 1486
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
V +P F +P V V G V +++ + ++Y +L G +EG
Sbjct: 1487 FVILADL-----LPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS---RLMTYRILEGNDEG 1538
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F ++ SG + + +L + + + N +VT V++ DVND V
Sbjct: 1539 Y-FRMDSLSGDLLALKELDYEDVRTFTMRIKGQDTDGNADVVT-LVVNLEDVNDCSPVFA 1596
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
++ V+E A + + +Y G+ R + I ++G
Sbjct: 1597 GEVGGEVMLRVEEPFLVAGVPVV----KLDVYDKDAGD-RLTFELSDEGERIFTIDDEGQ 1651
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ R V +T F T+ + D + +PP H T +
Sbjct: 1652 LIPT-------RSVNDITEPLSF-------------TVTVRD-SASPP---HVTSSRVTL 1687
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG--------KEMFDVDENTGVVKFI 849
K+G + +++ ++ DA G F+ +F + F +DE G ++ +
Sbjct: 1688 NFEKLGEALPVESRVRE-DAYIGMIVTFVPKVFPKSVFKITYPKDPAFSIDE-IGDIR-V 1744
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSS---EAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
LD EK++ Y L++ ++ G S + ++I + D NDN P F I RI++
Sbjct: 1745 AKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFTGI-----TRIYK 1799
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPL--FLIPENIPIGTTIIKLNALDLDSGLNG 964
N G ++ + N LD ++ G + ++P + P G + ++ LN
Sbjct: 1800 RINKNSLNGSPVLSL---NALDLDYERNGEVGFQIVPRDGPFGINPVD-EMIETTGNLNK 1855
Query: 965 QIRYEFN 971
+ YEF+
Sbjct: 1856 E-SYEFD 1861
Score = 55.2 bits (127), Expect = 1e-05
Identities = 54/201 (26%), Positives = 97/201 (48%), Gaps = 18/201 (8%)
Query: 725 DVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D TD AI+ D G I LD E + V E +KG I + NDN
Sbjct: 2043 DNTDMFAISPDTGVISPAVSLDYEMSSWVVLVVKVE-DKGGSPNIMQSYANITLLPVNDN 2101
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
PVF + Y I E +++G E+ + ATD D YT+ G+ + +D ++
Sbjct: 2102 SPVFAQSNYAFQISETAEVGNELA---FVTATDRDGDP---ITYTIEGDSGP-YIIDPSS 2154
Query: 844 GVVKFIGDSLDREKKI-MYKLSLVARDTGGL-SSEAELIIMIGDENDNKPEFNQIEENSK 901
G++ +L RE + +++ + + T G+ ++ ++++ I D+N++KP+F E+S
Sbjct: 2155 GII-----TLSREAPVNVWEYNFKVKATDGIFTATTDVLLDIIDQNNHKPQFTNCGESS- 2208
Query: 902 VRIHRETKLNGTAGFTIIEVK 922
R +E N +G +++V+
Sbjct: 2209 -RTVKEIAENLPSGQVLMQVQ 2228
Score = 54.4 bits (125), Expect = 2e-05
Identities = 54/200 (27%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSL--PP 1009
K A+D DS G +RY NS P S L F ++ G + R +
Sbjct: 1101 KALAVDADSESFGTVRYSINSASSNPSSDLP---------FSLDASSGQMKTTRVIKYSD 1151
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
+E+ + + A DGG + S+ + V ++N+ P F + Y F+V E + +G + A
Sbjct: 1152 RAEYTVALVATDGGGKSTTTSLVIKVFNINEP-PKFPQPKYEFSVPENKQVGTEIGAITA 1210
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
T AD N L Y I + D F ++ GV+S+ LD ET+ + L +
Sbjct: 1211 TYAD--PNTLLKYSITRGNIDDTFCVNS-KGVISLAKALDSETKASFTLDAMV----SHG 1263
Query: 1130 XXXXXXXXXXXXXDVNDNSP 1149
D+NDN P
Sbjct: 1264 TSNHTTVVQITVNDINDNWP 1283
Score = 54.0 bits (124), Expect = 3e-05
Identities = 39/121 (32%), Positives = 48/121 (39%), Gaps = 4/121 (3%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V DVNDH P F Y + E + +V A D D G+ +TY + PS
Sbjct: 2514 VNVTVIDVNDHTPTFNMETYECRIFENSPVGTGIIRVHAEDLDTGR---VTYSLHPSRDY 2570
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I G + DRE E +Y LT +A D G D ND P
Sbjct: 2571 QKFTIDTQRGTIRNAVVFDREEESRYSLTAIATDAG-SPPFSTQVFVKIDVLDANDQPPS 2629
Query: 1151 F 1151
F
Sbjct: 2630 F 2630
Score = 53.6 bits (123), Expect = 4e-05
Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 16/190 (8%)
Query: 733 AEDGTIFTQKPLDRE--KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
++ G + + KP + + + + +T++ V G + + I+D N+ P F +
Sbjct: 66 SDAGVVTSAKPFEYRIGESNTFTLTIVKRQRSQVFGGTAT-TLLVTIKDSNNFLPTFGSS 124
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDE-NTGVVKF 848
Y G +ME SK T +K A D D T + YT+ G K F N G +F
Sbjct: 125 VYNGTVMEGSKEDTVVKGLENCHAEDRD--TGGISSYTIISGNEKGYFKTSTINVGEERF 182
Query: 849 I-----GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSK 901
+ + R+ KL + ARD+G + ++ I + + N+N P+F + E +
Sbjct: 183 LQILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAM 242
Query: 902 VRIHRETKLN 911
V ET+LN
Sbjct: 243 VM--EETQLN 250
Score = 53.6 bits (123), Expect = 4e-05
Identities = 55/197 (27%), Positives = 92/197 (46%), Gaps = 20/197 (10%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV--FEHATYE 793
G + LD +K+ Y++TV+A ++G +V + I+D +PP +
Sbjct: 287 GVVILVGTLDYQKQSSYQLTVMAT-DRGSPRREAATKVILTIKDSQFSPPADSADPGANT 345
Query: 794 GFIMENSKIGTEIKMDN-------IIKATDADE-GTNALFMYTLFGEGKEMFDVDENTGV 845
+ + T ++ D + ATD D G N +Y+L G +F +D ++ V
Sbjct: 346 APVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYSLSGPEAGLFAIDPDSAV 405
Query: 846 VKFIGDSLDREK-KIMYKLSLVARDTG--GLSSEAELIIMIG--DENDNKPEFNQIEENS 900
V + +LD EK + L++ A D G LS+ A LI+ I DEN N P F+ +
Sbjct: 406 VT-LAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFD--PKAQ 462
Query: 901 KVRIHRETKLNGTAGFT 917
+ + +T L GT+ FT
Sbjct: 463 AISVKEDTAL-GTSIFT 478
Score = 53.6 bits (123), Expect = 4e-05
Identities = 83/362 (22%), Positives = 134/362 (37%), Gaps = 39/362 (10%)
Query: 992 FVINERHGHVIVARSLPPES-EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWY 1050
++I+ G + ++R P E+ + A DG V + + D N+H P F
Sbjct: 2148 YIIDPSSGIITLSREAPVNVWEYNFKVKATDG-IFTATTDVLLDIIDQNNHKPQFTNCGE 2206
Query: 1051 NFN----VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ + E + +VL +V ATD D G N + Y + TD F I TGV+
Sbjct: 2207 SSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELVIGFTD--FSIDNTTGVIKTRY 2264
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXX----XXXXXXXDVNDNSPKFYAF-------- 1154
LDRE K + V A+D G D NDN P F+
Sbjct: 2265 PLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQ 2324
Query: 1155 -----DELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
L+ K + D SN E + P K IE+ I TV ++ T F+
Sbjct: 2325 KAPVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDKFAIEKTTGI-VTVKTDLSSFTGFV-- 2381
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
L + S ++G ++++ V V + P+F Y + + EN
Sbjct: 2382 --TLQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV-------EPPMFERHLYNISVREN 2432
Query: 1270 VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
+ + N + Y L+EN + + I+ G++ D E + Y
Sbjct: 2433 AAVGTTIGQIRAVSQ-NNRPIMYQPLHEN-PNAKEEIGIEIDTGSIVTSSKLDYESVNNY 2490
Query: 1330 EV 1331
E+
Sbjct: 2491 EL 2492
Score = 52.0 bits (119), Expect = 1e-04
Identities = 79/356 (22%), Positives = 145/356 (40%), Gaps = 26/356 (7%)
Query: 992 FVINERHGHVIVARSLPPE---SEFRLNISALDGGN--LNDNISVRVFVKDV--NDHFPV 1044
F I+ V +A +L E + L ++A D G+ L+ + + V++KDV N + PV
Sbjct: 397 FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPV 456
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
F +V+E + ATD D G + L Y + + ++ TGV++
Sbjct: 457 FDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTT 516
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
DR+T + + A D G V+D P+F +
Sbjct: 517 AAMFDRKTNPVVEVVIAAHDKG-TFPRTSKFYLLIQVEKVDDMYPEF--------TQPAY 567
Query: 1165 ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
+ + + + E+ ++ ++ AT EN I + V ND + G+I + K +
Sbjct: 568 SATVLDGSPENTFVVALH-ATDYENTQIEYRLVNVGVNDLFQVERSTGVIRTAREPAKTR 626
Query: 1225 QNLGLPSL----SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
+ L S +T+ ++ + P F + +E+++ EN LV L
Sbjct: 627 GDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVCLA 686
Query: 1281 LTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
T+ + + Y I + F +D +G ++RS D E+++ Y V V+AE
Sbjct: 687 ATDG-DLGSITYSITGGGN----GKFAVDQHSGKFSVLRSFDYELENGYIVQVQAE 737
Score = 51.6 bits (118), Expect = 2e-04
Identities = 47/169 (27%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
Query: 220 AIDQDL-GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D G L Y L SG + LF++D + + L LD + + L V A
Sbjct: 373 ATDNDPPGPNQRLLYSL-SGPEAGLFAIDPDSAVVTLAAALDYEKGPTV----INLTVTA 427
Query: 279 SQLNNPLKTAQAR--VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ +P +A A V I+ +D N NLP F+ IS+ E+ G S+ ATD+D G
Sbjct: 428 TDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSG 487
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+GE Y + +G + V + DR+ + + + + A +
Sbjct: 488 PDGELEYSMVAGEGVGYVILNETTGVVTTAAMFDRKTNPVVEVVIAAHD 536
Score = 49.6 bits (113), Expect = 6e-04
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 9/112 (8%)
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GENGEFTYQL 345
+A V + L+D+ND P F Y ++ EN G +V + A D D G N + Y L
Sbjct: 2824 RAEVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIYSL 2883
Query: 346 DDPKGAF-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN---PSVVGT 393
+D G + +ID SG +T + ++DREA KV + T+ P++ GT
Sbjct: 2884 EDNNGGYVTIDSSSGLVT--SIKMVDREALQEDSFKVTVRATDQGQPALSGT 2933
Score = 48.8 bits (111), Expect = 0.001
Identities = 106/443 (23%), Positives = 176/443 (39%), Gaps = 74/443 (16%)
Query: 1029 ISVRVFVKDVNDHFPVF----KKTWYNFNVEEAQYT-----RR-----VLGKVDATDADF 1074
++V + + DVND+ PVF T N + T RR + K A DAD
Sbjct: 1050 VAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKARRFTYYVIYEKALAVDADS 1109
Query: 1075 GQNANLTYFIQPSDT----DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
+ Y I + + DLPF + +G + + +Y + +VA D G
Sbjct: 1110 ESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTRVIKYSDRAEYTVALVATDGGGKST 1169
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE-N 1189
++N+ PKF E+ PE ++ I AT + N
Sbjct: 1170 TTSLVIKVF---NINE-PPKFP--QPKYEFSVPENKQVGTE-------IGAITATYADPN 1216
Query: 1190 APIGTTVAKVFANDTDFIGNGNGLI-LYSLPQRKNQQNLGLPSLSS------TAILMVTV 1242
+ ++ + +DT F N G+I L + + + L ++ S T ++ +TV
Sbjct: 1217 TLLKYSITRGNIDDT-FCVNSKGVISLAKALDSETKASFTLDAMVSHGTSNHTTVVQITV 1275
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYYILNENDT 1300
D+ D + + PV Y +E+ E+ ELV + T+ + Y I+ D
Sbjct: 1276 NDINDNWPIME-PV-----YNVEVREDQAPGTELVKVVATDLDGGVGGTITYTIIQTQDI 1329
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
F ++ G + LV+ D E + K H++Y AED G T
Sbjct: 1330 GSSSLFAVNASTGVITLVQKLDAE-----------DINK------HVLYVKAED--GGPT 1370
Query: 1361 -KYDV--KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRT 1417
KY KVVV + DVND++P+F++ + ++P P + V Q+ + +
Sbjct: 1371 PKYAAITKVVVLVGDVNDHAPRFSSSQ--YLASVPYEFPVNFHVFQVIATDADSGSNAEL 1428
Query: 1418 VRADT--DELVFFERLSLNGLTS 1438
A T +E F+ S NGL S
Sbjct: 1429 TYAITGGNEDGIFKINSENGLVS 1451
Score = 48.4 bits (110), Expect = 0.002
Identities = 60/223 (26%), Positives = 93/223 (41%), Gaps = 28/223 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ G + ++ A D D+G NG + Y F + P + F I R G
Sbjct: 2959 VSESTRTGVAVTRVEATDEDTGYNGMMNY-FIVQGNEPYA------------FFIEPRTG 3005
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN---LNDNIS-VRVFVKDVNDHFPVFKKTWYNFN 1053
V V+ L ES+ + L + D G L DN++ V V + D N H P F + + +
Sbjct: 3006 VVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHEAS 3065
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP-----LTGVLSVNGEL 1108
V E + + ATD D + + + I D + F I+ +T +++V G+L
Sbjct: 3066 VREDVPLGYSVLTIKATDIDTVDSFH-RFLISSGDEENMFTITESESEKMTAIITVRGKL 3124
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
DRE + Y + VV D D NDN P F
Sbjct: 3125 DRERKSFYNMIVVVND---TSGQSDECIVKITVTDANDNGPHF 3164
Score = 47.6 bits (108), Expect = 0.003
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 14/140 (10%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y ++ GND F +DS++G L KELD + TF ++++ +
Sbjct: 1527 MTYRILEGNDEGYFRMDSLSGDLLALKELDYE-----DVRTFTMRIKGQDTDGNADVVTL 1581
Query: 291 RVEIELLDLNDNLPEF--EVDFYNISIVEN--LPNGFSVLQVMATDKDQGENGEFTYQL- 345
V +E D+ND P F EV + VE L G V+++ DKD G+ T++L
Sbjct: 1582 VVNLE--DVNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGD--RLTFELS 1637
Query: 346 DDPKGAFSIDPRSGWLTVRN 365
D+ + F+ID + R+
Sbjct: 1638 DEGERIFTIDDEGQLIPTRS 1657
Score = 47.6 bits (108), Expect = 0.003
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS+D + G + + K LD + + + T ++ +A + + + V I ++D+NDN+
Sbjct: 1734 FSIDEI-GDIRVAKPLDFEKQVSY---TLTVR-EAESIGSSPRVFDRVVVISVIDVNDNV 1788
Query: 304 PEFE-VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
P F + I +N NG VL + A D D NGE +Q+ G F I+P
Sbjct: 1789 PRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQIVPRDGPFGINP 1842
Score = 47.2 bits (107), Expect = 0.003
Identities = 80/364 (21%), Positives = 143/364 (39%), Gaps = 42/364 (11%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGDDLVRIGA-----GLNQISAYLSVTVYIEDV--NDNVPI 96
+D DS VV D+++G ++ + G +SA + VYI+DV N N+P+
Sbjct: 399 IDPDSA--VVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPV 456
Query: 97 FLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRG----LTIFKDIR----- 145
F ++V E T G F GP + ++ G I +
Sbjct: 457 FDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTT 516
Query: 146 AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLD-YDAGDKEFQLVIMAS 204
A D+ P +V +++ +D G F S ++ + KV D Y + +
Sbjct: 517 AAMFDRKTNPVVEV---VIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVLD 573
Query: 205 GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAE 264
G E F +HA D + + Y L++ LF ++ G + +E
Sbjct: 574 GS---PENTFVVALHATDYE---NTQIEYRLVNVGVNDLFQVERSTGVIRTARE-PAKTR 626
Query: 265 HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS 324
+ + N +++ ++ + A V I + + +P F + I + EN S
Sbjct: 627 GDQEFNQLIIEA-----SDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDS 681
Query: 325 VLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
++ + ATD G+ G TY + G F++D SG +V D E + ++V A
Sbjct: 682 LVCLAATD---GDLGSITYSITGGGNGKFAVDQHSGKFSVLRS--FDYELENGYIVQVQA 736
Query: 384 KETN 387
+ N
Sbjct: 737 ETPN 740
Score = 46.8 bits (106), Expect = 0.005
Identities = 76/321 (23%), Positives = 121/321 (37%), Gaps = 37/321 (11%)
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
D F I + G + V LD E + Y LTV ++ DVNDN P
Sbjct: 1731 DPAFSIDEI-GDIRVAKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVP 1789
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV----AKVFANDTD 1205
+F + +K + L N V+ + E N +G + N D
Sbjct: 1790 RFTGITRI--YKRINKNSL---NGSPVLSLNALDLDYERNGEVGFQIVPRDGPFGINPVD 1844
Query: 1206 -FIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVT-VADVPDEVEMSDKPVFISRYYE 1263
I L S + G+P L+ST I MV VA+VP E+ D Y
Sbjct: 1845 EMIETTGNLNKESYEFDVYAFDYGIPRLNSTTIPMVVHVAEVPPIFEVLDND---HNMYR 1901
Query: 1264 LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
E E + EL+ Y + Y I + N +R +F I GTL
Sbjct: 1902 FETAETSHGG-ELIGTVKAVSYSKALIAYEITSGN---VRNSFKI----GTL------TG 1947
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
E++ + Y+ + A +++ + ++ V++ +K++NDN P+FT
Sbjct: 1948 EIRHNNFMNYEIHENVYN------LTVTASELIPRGHQTEIPVIIHLKNINDNYPRFTKS 2001
Query: 1384 NRPLVTAIPTTAPFGYQVMQL 1404
TA+ P G ++Q+
Sbjct: 2002 --LFTTAVNEDVPVGTSILQV 2020
Score = 46.0 bits (104), Expect = 0.008
Identities = 72/285 (25%), Positives = 119/285 (41%), Gaps = 31/285 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E++P+GT+I+++ A D D + P +L+ +++ F I+ G
Sbjct: 2007 VNEDVPVGTSILQVTATDCDC----------SKSCLCAPGELTY-SIDNTDMFAISPDTG 2055
Query: 1000 HVIVARSLPPE--SEFRLNISALD-GGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ A SL E S L + D GG+ N S + + VND+ PVF ++ Y F +
Sbjct: 2056 VISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVNDNSPVFAQSNYAFQIS 2115
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E L V ATD D +TY I+ D+ P+ I P +G+++++ E +
Sbjct: 2116 ETAEVGNELAFVTATDRD---GDPITYTIE-GDSG-PYIIDPSSGIITLSREAPVNVWE- 2169
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y V A D D N++ P+F E E++ N S
Sbjct: 2170 YNFKVKATDG----IFTATTDVLLDIIDQNNHKPQFTNCGE----SSRTVKEIA-ENLPS 2220
Query: 1176 VMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLP 1219
++ +AT E+ G ++ TDF I N G+I P
Sbjct: 2221 GQVLMQVQATDEDRGLNGEVEYELVIGFTDFSIDNTTGVIKTRYP 2265
Score = 45.6 bits (103), Expect = 0.011
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D G + Y L D + F++D+ G++ D + E + + L
Sbjct: 2550 VHAEDLDTG---RVTYSLHPSRDYQKFTIDTQRGTIRNAVVFDREEE-----SRYSLTAI 2601
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
A+ +P + Q V+I++LD ND P F S+ E+ P G SV + + D D
Sbjct: 2602 ATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSSVYKAVILDSD 2658
Score = 42.3 bits (95), Expect = 0.099
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE-FTYQLDD-PKGA 351
I++ D NDN P F Y +S+ E P G SV+ V A D D E TY +D +
Sbjct: 2726 IKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSIDKRGEQY 2785
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F I +G +T + LDRE VYA +
Sbjct: 2786 FRISSSTGEITC-GASPLDREKLLYYFFTVYASD 2818
Score = 42.3 bits (95), Expect = 0.099
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 20/192 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL---DSVNGSLFLEKELDLDAEHNLQANTFVL 274
I A D D V + R+ + SG++ +F++ +S + + LD E N V+
Sbjct: 3079 IKATDIDT-VDSFHRFLISSGDEENMFTITESESEKMTAIITVRGKLDRERKSFYNMIVV 3137
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
S ++ + V+I + D NDN P F+ +++ + EN+ + V + ATD D
Sbjct: 3138 VNDTSGQSD-----ECIVKITVTDANDNGPHFQPSYFSGFVRENIDSEQFVTTISATDPD 3192
Query: 335 QGENG-EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP--SVV 391
NG FT+ L + K +S +++ TV A + +E P ++
Sbjct: 3193 MPSNGPPFTFTLINTK-------QSSQFRIKDSTVTSNTA-QVFAYGTFDRELTPFYKLL 3244
Query: 392 GTFADSQRIAKW 403
+DS R A W
Sbjct: 3245 VNASDSGRPAMW 3256
Score = 41.9 bits (94), Expect = 0.13
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 12/107 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D DLG ++ Y + G + K F++D +G + + D + E N +++QVQA
Sbjct: 687 ATDGDLG---SITYSITGGGNGK-FAVDQHSGKFSVLRSFDYELE-----NGYIVQVQAE 737
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
N KT+ A V++ + +++D LP F Y +++ E G ++L
Sbjct: 738 TPN--AKTSSANVKLIISNIDD-LPSFAKPEYTLTVPEGTTPGTTIL 781
Score = 41.9 bits (94), Expect = 0.13
Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM---YTL 829
V I++++ NDN P F + + + E+ +GT I + ATD D + L T
Sbjct: 1984 VIIHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQ---VTATDCDCSKSCLCAPGELTY 2040
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS--EAELIIMIGDEN 887
+ +MF + +TGV+ SLD E L + D GG + ++ I + N
Sbjct: 2041 SIDNTDMFAISPDTGVIS-PAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVN 2099
Query: 888 DNKPEFNQ 895
DN P F Q
Sbjct: 2100 DNSPVFAQ 2107
Score = 40.7 bits (91), Expect = 0.30
Identities = 43/193 (22%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E++P+G +++ + A D+D+ ++ R+ +S + + E ++ I G
Sbjct: 3066 VREDVPLGYSVLTIKATDIDT-VDSFHRFLISSGD--EENMFTITESESEKMTAIITVRG 3122
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ R +S + + + D +D V++ V D ND+ P F+ ++++ V E
Sbjct: 3123 KLDRER----KSFYNMIVVVNDTSGQSDECIVKITVTDANDNGPHFQPSYFSGFVRENID 3178
Query: 1060 TRRVLGKVDATDADFGQNA-NLTYFIQPSDTDLPFEI-----SPLTGVLSVNGELDRETE 1113
+ + + + ATD D N T+ + + F I + T + G DRE
Sbjct: 3179 SEQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQVFAYGTFDRELT 3238
Query: 1114 DKYILTVVARDNG 1126
Y L V A D+G
Sbjct: 3239 PFYKLLVNASDSG 3251
Score = 36.7 bits (81), Expect = 4.9
Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 10/173 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD-LDAEHNLQANTFVLQV 276
+ AID D G A + Y + +D+ F+++ G + ++ +L LQ +
Sbjct: 2335 VKAIDLDTGSNAKVEYTFVEPSDK--FAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVP 2392
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ + Q V I++ + P FE YNIS+ EN G ++ Q+ A ++
Sbjct: 2393 ITVSVGEDDRDRQTLVVIDVTTVEP--PMFERHLYNISVRENAAVGTTIGQIRAVSQN-- 2448
Query: 337 ENGEFTYQ--LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
N YQ ++P I ++ + LD E+ ++ ++ A ET+
Sbjct: 2449 -NRPIMYQPLHENPNAKEEIGIEIDTGSIVTSSKLDYESVNNYELQFVAVETS 2500
Score = 35.9 bits (79), Expect = 8.6
Identities = 40/167 (23%), Positives = 70/167 (41%), Gaps = 20/167 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT+I A D DSG +G++ Y S A E Y ++NE G
Sbjct: 466 VKEDTALGTSIFTAKATDEDSGPDGELEY-------------SMVAGEGVGYVILNETTG 512
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V A ++ + I+A D G + + V+ V+D +P F + Y+ V
Sbjct: 513 VVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVL 572
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
+ + + ATD +N + Y + + F++ TGV+
Sbjct: 573 DGSPENTFVVALHATDY---ENTQIEYRLVNVGVNDLFQVERSTGVI 616
Score = 35.9 bits (79), Expect = 8.6
Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 14/161 (8%)
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
Y++TV A + G VT+ + P F A Y I E+ IG +
Sbjct: 931 YKLTVKAT-DTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESLVIGNSVLQ--- 986
Query: 812 IKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD- 869
+ AT A Y++ G K + F +D TG + + LD E Y L++ A
Sbjct: 987 VTATGP-----AAITYSIVGGNKNDAFRIDRTTGQIA-VNKPLDYEVLQSYVLNVRATCE 1040
Query: 870 --TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
T +++E + I + D NDN P F + V ++ T
Sbjct: 1041 TYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYT 1081
>UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|Rep:
Paraxial protocadherin - Xenopus laevis (African clawed
frog)
Length = 979
Score = 107 bits (257), Expect = 2e-21
Identities = 122/471 (25%), Positives = 205/471 (43%), Gaps = 40/471 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+NV+V + D ND++P F PS + + ++ VGT I A+D D+G N + + +
Sbjct: 113 LNVKVEVRDINDHSPHF-PSEIMHVEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQISNN 171
Query: 503 SNLTITSPFKIN--PNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
S+ +I + + V + E ++ + + + A D PS AVV I V
Sbjct: 172 SHFSIDVLTRADGVKYADLVLMRELDREIQPTYIMELLAMDGGV-PSLS--GTAVVNIRV 228
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY----- 614
+ P F + + + +G + ++ D + V+ ++++G+
Sbjct: 229 LDFNDNS----PVFERSTIAVDLVEDAPLGYLLLELHATD--DDEGVNGEIVYGFSTLAS 282
Query: 615 -EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
E F + R+G +T+ + + Y+FE A N L+ TVH++DVND
Sbjct: 283 QEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGPNPLTATCKVTVHILDVNDN 342
Query: 673 RGVL----LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ L ++ + + + + I I T+ +S G VR + +
Sbjct: 343 TPAITITPLTTVNAGVAYIPETATKENFIALISTTDRAS---GSNGQVRCTLYGHEHFKL 399
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
A + I T LDRE Y +TV+AE + G S T+ + DENDN PVF
Sbjct: 400 QQAYEDSYMIVTTSTLDRENIAAYSLTVVAE-DLGFPSLKTKKYYTVKVSDENDNAPVFS 458
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEGKEMF-DVDEN 842
YE I+EN+ G+ I + A D+D N Y L G+ F +D +
Sbjct: 459 KPQYEASILENNAPGSYI---TTVIARDSDSDQNGKVNYRLVDAKVMGQSLTTFVSLDAD 515
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+GV++ + SLD EK + A D G LS+ +L + I D+NDN P
Sbjct: 516 SGVLRAV-RSLDYEKLKQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNCP 565
Score = 93.9 bits (223), Expect = 3e-17
Identities = 111/453 (24%), Positives = 188/453 (41%), Gaps = 20/453 (4%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +LD NDN+PVF S + + +A +G ++ ++ A D D G NG ++Y ++
Sbjct: 224 VNIRVLDFNDNSPVFERSTI-AVDLVEDAPLGYLLLELHATDDDEGVNGEIVYGFSTLAS 282
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ FKIN TG+V++ E + + V+A D NP + V ++V
Sbjct: 283 QEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGPNPLTATCKVTVHILDVNDN 342
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND-AFEQNDVSYDLLHGYEEGVPFA 621
T + A + + + I D A N L+G+E
Sbjct: 343 TPAITITPLTTVNAGVAY-IPETATKENFIALISTTDRASGSNGQVRCTLYGHEHFKLQQ 401
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKGA 680
E S +I L R N Y VA +L TV V D ND V K
Sbjct: 402 AYEDSYMIVTTSTLDRENIAAYSLTVVAEDLGFPSLKTKKYYTVKVSDENDNAPVFSKPQ 461
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ--QDVTDDIAI-AEDGT 737
+ I ++ N+ G+ I + + S NG N R + A Q +T +++ A+ G
Sbjct: 462 YEASI--LENNAPGSYITTVIARDSDSDQ-NGKVNYRLVDAKVMGQSLTTFVSLDADSGV 518
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ + LD EK + A N G+ + Q+ + I D+NDN PV +
Sbjct: 519 LRAVRSLDYEKLKQLDFEIEAADN-GIPQLSTRVQLNLRIVDQNDNCPVITNPLLNNGSG 577
Query: 798 ENSKIGTEIKMDNII---KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
E + + ++ KA D+DEG N+ YT+ + +F +++ +G V F+ L+
Sbjct: 578 E-VLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILRDPSRLFAINKESGEV-FLKKQLN 635
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
+ + + D G LS+ A + ++ D
Sbjct: 636 SDHSEDLSIVVAVYDLGRPSLSTNATVKFILTD 668
Score = 86.2 bits (204), Expect = 6e-15
Identities = 139/593 (23%), Positives = 228/593 (38%), Gaps = 75/593 (12%)
Query: 579 EFWVGSNVGIGTSVGQIRVNDAFEQNDV---SYDLLHGYEEGVPFAVEERSGVITVVDDL 635
++++ GT + + + F D+ ++ L+ + + V E G +++++ +
Sbjct: 26 QYYIDEEEPPGTVIAVLSQHSIFNTTDIPATNFRLMKQFNNSL-IGVRESDGQLSIMERI 84
Query: 636 SRYNRPMYDFEAVALQENANLSI----VTNATVHVVDVNDERGVLLKGAHSPI-IFHVKE 690
R + + S + N V V D+ND H P I HV E
Sbjct: 85 DREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDH------SPHFPSEIMHV-E 137
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIAIAEDGTIFTQ----KPLD 745
S +++G ++ G+ +++ F I+N + D+ DG + + LD
Sbjct: 138 VSESSSVGTRIPLEIAIDEDVGSNSIQNFQISNNSHFSIDVLTRADGVKYADLVLMRELD 197
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE + Y M ++A + GV S +G V I + D NDN PVFE +T ++E++ +G
Sbjct: 198 REIQPTYIMELLA-MDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLGYL 256
Query: 806 IKMDNIIKATDADEGTNALFMY---TLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
+ + ATD DEG N +Y TL E +++F ++ TG V G +D E K Y
Sbjct: 257 LLE---LHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGSVTLEGQ-VDFETKQTY 312
Query: 862 KLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
+ + A+D G N + KV +H + T TI +
Sbjct: 313 EFEVQAQDLGP---------------------NPLTATCKVTVHILDVNDNTPAITITPL 351
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
N G + IPE I ++ D SG NGQ+R + +
Sbjct: 352 TTVNA--------GVAY-IPETATKENFIALISTTDRASGSNGQVRCTLYGHEHFKLQQA 402
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
D+ + ++ + I A SL +E L +L V V D ND+
Sbjct: 403 YEDSYMIVTTSTLDREN---IAAYSLTVVAE------DLGFPSLKTKKYYTVKVSDENDN 453
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-----FIQPSDTDLPFEIS 1096
PVF K Y ++ E + V A D+D QN + Y + +
Sbjct: 454 APVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQSLTTFVSLD 513
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+GVL LD E + + A DNG D NDN P
Sbjct: 514 ADSGVLRAVRSLDYEKLKQLDFEIEAADNG-IPQLSTRVQLNLRIVDQNDNCP 565
Score = 79.4 bits (187), Expect = 7e-13
Identities = 48/175 (27%), Positives = 90/175 (51%), Gaps = 8/175 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID+D+G + +++ + + + L +G + + L + + +Q T+++++ A
Sbjct: 153 AIDEDVGSNSIQNFQISNNSHFSIDVLTRADGVKYADLVLMRELDREIQP-TYIMELLAM 211
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + A V I +LD NDN P FE + +VE+ P G+ +L++ ATD D+G NG
Sbjct: 212 DGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLGYLLLELHATDDDEGVNG 271
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
E Y + + F I+ R+G +T+ Q +D E + +V A++ P+
Sbjct: 272 EIVYGFSTLASQEVRQLFKINSRTGSVTLEGQ--VDFETKQTYEFEVQAQDLGPN 324
Score = 60.5 bits (140), Expect = 3e-07
Identities = 101/420 (24%), Positives = 168/420 (40%), Gaps = 50/420 (11%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E+ P+G +++L+A D D G+NG+I Y F S L++ EV++ F IN R G V
Sbjct: 249 EDAPLGYLLLELHATDDDEGVNGEIVYGF--------STLASQ--EVRQLFKINSRTGSV 298
Query: 1002 IVARSLPPES----EFRLNISALDGGNLNDNISVRVFVKDVNDHFP---VFKKTWYNFNV 1054
+ + E+ EF + L L V V + DVND+ P + T N V
Sbjct: 299 TLEGQVDFETKQTYEFEVQAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGV 358
Query: 1055 ---EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
E + + TD G N + + + + + ++ LDRE
Sbjct: 359 AYIPETATKENFIALISTTDRASGSNGQVRCTLYGHEHFKLQQAYEDSYMIVTTSTLDRE 418
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
Y LTVVA D G D NDN+P F EA L N+
Sbjct: 419 NIAAYSLTVVAEDLG-FPSLKTKKYYTVKVSDENDNAPVF-------SKPQYEASILENN 470
Query: 1172 NFESVMMIPVYK-ATIEENAPIGTTV--AKVFAND-TDFIG--NGNGLI--LYSLPQRKN 1223
S + + + + ++N + + AKV T F+ +G++ + SL K
Sbjct: 471 APGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKL 530
Query: 1224 QQ--------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE--LEIEENVNAP 1273
+Q + G+P LS+ L + + D D + P+ + E L I N
Sbjct: 531 KQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYL 590
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
V + ++ N ++ Y IL D R F I+ +G ++L + + + + ++V
Sbjct: 591 VFQLKAEDSDEGHNSQLFYTILR----DPSRLFAINKESGEVFLKKQLNSDHSEDLSIVV 646
Score = 56.8 bits (131), Expect = 4e-06
Identities = 84/336 (25%), Positives = 133/336 (39%), Gaps = 34/336 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPY---HVTVDELTPTGEKA-FIFLIAPI---- 124
G N ++A VTV+I DVNDN P TP + V + T K FI LI+
Sbjct: 322 GPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIALISTTDRAS 381
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
G + + T+ G FK +A++ S + ++ A E P L
Sbjct: 382 GSNGQVRCTL-YGHEHFKLQQAYEDSYMIVTTSTLDRENIAAYSLTVVA-EDLGFPSLKT 439
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEIL-------FPEPIHAIDQDLGVGATLRYELIS 237
+K D+ + S + IL + + A D D + Y L+
Sbjct: 440 KKYYTVKVSDENDNAPVF-SKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVD 498
Query: 238 ----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
G F SLD+ +G L + LD + L +++A+ P + + ++
Sbjct: 499 AKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLD-----FEIEAADNGIPQLSTRVQL 553
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENL-----PNGFSVLQVMATDKDQGENGEFTYQ-LD 346
+ ++D NDN P N E L P + V Q+ A D D+G N + Y L
Sbjct: 554 NLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILR 613
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
DP F+I+ SG + ++ Q D S+ + VY
Sbjct: 614 DPSRLFAINKESGEVFLKKQLNSDHSEDLSIVVAVY 649
Score = 56.4 bits (130), Expect = 6e-06
Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 20/180 (11%)
Query: 218 IHAIDQDLGVGATLRY---ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+HA D D GV + Y L S R+LF ++S GS+ LE ++D + + T+
Sbjct: 260 LHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQ-----TYEF 314
Query: 275 QVQASQLN-NPLKTAQARVEIELLDLNDNLPEFEV---DFYNISIV---ENLPNGFSVLQ 327
+VQA L NPL TA +V + +LD+NDN P + N + E +
Sbjct: 315 EVQAQDLGPNPL-TATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIAL 373
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDP--RSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ TD+ G NG+ L + F + ++ V T LDRE ++ + V A++
Sbjct: 374 ISTTDRASGSNGQVRCTLYGHE-HFKLQQAYEDSYMIVTTST-LDRENIAAYSLTVVAED 431
Score = 49.6 bits (113), Expect = 6e-04
Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 24/156 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G+PSLS TA++ + V D D + PVF +++ E+ L+ L+ T+ E
Sbjct: 214 GVPSLSGTAVVNIRVLDFND-----NSPVFERSTIAVDLVEDAPLGYLLLELHATDDDEG 268
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y ++R+ F I+ R G++ L D E K TYE V+
Sbjct: 269 VNGEIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQ----------- 317
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
A+D+ KV V I DVNDN+P T
Sbjct: 318 ------AQDLGPNPLTATCKVTVHILDVNDNTPAIT 347
Score = 48.8 bits (111), Expect = 0.001
Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 11/130 (8%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
++V+V V+D+NDH P F + V E+ + A D D G N+ + I
Sbjct: 113 LNVKVEVRDINDHSPHFPSEIMHVEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQI---S 169
Query: 1089 TDLPFEISPLT---GV----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
+ F I LT GV L + ELDRE + YI+ ++A D G
Sbjct: 170 NNSHFSIDVLTRADGVKYADLVLMRELDREIQPTYIMELLAMDGG-VPSLSGTAVVNIRV 228
Query: 1142 XDVNDNSPKF 1151
D NDNSP F
Sbjct: 229 LDFNDNSPVF 238
Score = 43.2 bits (97), Expect = 0.056
Identities = 45/190 (23%), Positives = 87/190 (45%), Gaps = 14/190 (7%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQV 276
H+I + AT + L+ + L + +G L + + +D + +L N + V
Sbjct: 45 HSIFNTTDIPAT-NFRLMKQFNNSLIGVRESDGQLSIMERIDREQICRQSLHCNLALDVV 103
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
S+ + L V++E+ D+ND+ P F + ++ + E+ G + +A D+D G
Sbjct: 104 SFSKGHFKL----LNVKVEVRDINDHSPHFPSEIMHVEVSESSSVGTRIPLEIAIDEDVG 159
Query: 337 ENGEFTYQLDDPKGAFSID--PRSGWLTVRNQTV---LDREAHSSLRMKVYAKETN-PSV 390
N +Q+ + FSID R+ + + + LDRE + M++ A + PS+
Sbjct: 160 SNSIQNFQISN-NSHFSIDVLTRADGVKYADLVLMRELDREIQPTYIMELLAMDGGVPSL 218
Query: 391 VGTFADSQRI 400
GT + R+
Sbjct: 219 SGTAVVNIRV 228
>UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260;
Amniota|Rep: Protocadherin beta 1 precursor - Homo
sapiens (Human)
Length = 818
Score = 107 bits (257), Expect = 2e-21
Identities = 129/495 (26%), Positives = 200/495 (40%), Gaps = 58/495 (11%)
Query: 936 PLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN 995
PL IPE+ P+G+ +A DLD GLNG Y ++ Y R+
Sbjct: 138 PLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANGYFHLHT---------RFCSHG 188
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
++ +++ + L E E L I+A+DGG+ + + V V DVNDH P F + Y
Sbjct: 189 PKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYR 248
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELD 1109
V E ++ V A D D G N +TY + P F+I P G + + G LD
Sbjct: 249 AQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDPQNGEVRLRGPLD 308
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY---AFDELLEWKHPE-A 1165
E + Y + + A D G DVNDN P+ L E P+
Sbjct: 309 FEAIETYDIDIQATDGG---GLSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTV 365
Query: 1166 DELSNHNFESVMMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKN 1223
L + + + E+ P I T ++ TD + + Y++
Sbjct: 366 VALFTIRDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNI--TIV 423
Query: 1224 QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
+ G PSLS+ ++ V ++DV D + P+F Y L + EN N+P + E
Sbjct: 424 AMDTGPPSLSAETMIEVLISDVND-----NPPIFREDSYILTVREN-NSPAVFIGKVHAE 477
Query: 1284 HY---ENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
EN ++ Y +L D + I+ NG LY +R+ D E ++ +V+A
Sbjct: 478 DLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTMDYEAIQDFQFVVKATDG 537
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP----KFTNGNRPLVTAIPTT 1394
+ L ++ V+VVV D NDN P NG P +P +
Sbjct: 538 GF---------------LSLSSQVTVRVVV--LDDNDNRPMILYPLQNGTLPCNDLVPRS 580
Query: 1395 APFGYQVMQLKGAIG 1409
A GY V ++ G
Sbjct: 581 AEAGYLVTKVVAVDG 595
Score = 96.7 bits (230), Expect = 4e-18
Identities = 119/499 (23%), Positives = 198/499 (39%), Gaps = 34/499 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E L SF EV + D NDN PVF+ + + +G+ A D D+G NG+
Sbjct: 112 EPLQSF-RAEVRVFDINDNAPVFLNKEPL-LKIPESTPLGSRFPLQSAQDLDVGLNGLQN 169
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLA 553
Y L + + F + V P+ L + A D + P +
Sbjct: 170 YTLSANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIH 229
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
VV ++V +P F Y V N G+ V + D E + ++Y L
Sbjct: 230 VVVLDVN-------DHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLA 282
Query: 612 HGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
E + F ++ ++G + + L YD + A + LS + V VVDVN
Sbjct: 283 QNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQAT-DGGGLSAHSKVLVEVVDVN 341
Query: 671 DERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D V++ SP+ E+S + +F I G V +
Sbjct: 342 DNPPEVMVSSVSSPL----PEDSPPQTVVALFTIRDRDIRVGG--KVTCFLREDLPFVIK 395
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
++ T + LDRE+ Y +T++A + G S + + + I D NDNPP+F
Sbjct: 396 PTFGNSYSLVTDRSLDREEVSGYNITIVA-MDTGPPSLSAETMIEVLISDVNDNPPIFRE 454
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDENTGV 845
+Y + EN+ I + A D D G NA Y+L G+ + N+G
Sbjct: 455 DSYILTVRENNSPAVFI---GKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGN 511
Query: 846 VKFIG-DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
K ++D E ++ + A D G LSS+ + +++ D+NDN+P +N +
Sbjct: 512 GKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTL 571
Query: 903 RIHRETKLNGTAGFTIIEV 921
+ + AG+ + +V
Sbjct: 572 PCNDLVPRSAEAGYLVTKV 590
Score = 72.9 bits (171), Expect = 6e-11
Identities = 104/458 (22%), Positives = 190/458 (41%), Gaps = 35/458 (7%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V +LD ND+ P F +Y + N+ G+++ V AVD D G N + Y L +
Sbjct: 227 HIHVVVLDVNDHVPQF-SRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNP 285
Query: 504 NLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTR 561
I F+I+P G V + E + + ++A+D + + + VV +
Sbjct: 286 E-AILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVN--- 341
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
+ P P+ M + + + T V + D V + E +PF
Sbjct: 342 ----DNP--PEVMVSSVSSPLPEDSPPQTVVALFTIRD--RDIRVGGKVTCFLREDLPFV 393
Query: 622 VEERSG-VITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
++ G ++V D L R Y+ VA+ +LS T V + DVND +
Sbjct: 394 IKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFR 453
Query: 678 KGAHSPIIFHVKENSAGAA-IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA--- 733
+ ++ I V+EN++ A IG++ H + N L D++ I+
Sbjct: 454 EDSY---ILTVRENNSPAVFIGKV-HAEDLDLGENAQITYSLLPPKNGDLSVFAYISINS 509
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+G ++ + +D E ++ V A + G +S + V + + D+NDN P+ +
Sbjct: 510 GNGKLYALRTMDYEAIQDFQFVVKAT-DGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQN 568
Query: 794 GFIMENSKIGTEIKMDNIIK---ATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
G + N + + ++ A D D G N+ Y L +F V G + +
Sbjct: 569 GTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNGEIHTL 628
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
+R+ +M KL ++ +D G LS+ L I++ D
Sbjct: 629 RQISERD-PMMQKLIILVQDHGQPALSTTVSLNILLVD 665
Score = 71.7 bits (168), Expect = 1e-10
Identities = 54/172 (31%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQVQ 277
A D D+G+ Y L + L + +G + E L+ LD E + N L +
Sbjct: 157 AQDLDVGLNGLQNYTLSANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVN---LTIT 213
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P K+ A + + +LD+ND++P+F Y + EN PNG V V A D D+G
Sbjct: 214 AVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGT 273
Query: 338 NGEFTYQL-DDPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N TY L +P+ F IDP++G VR + LD EA + + + A +
Sbjct: 274 NKAITYSLAQNPEAILKTFQIDPQNG--EVRLRGPLDFEAIETYDIDIQATD 323
Score = 60.5 bits (140), Expect = 3e-07
Identities = 90/354 (25%), Positives = 154/354 (43%), Gaps = 33/354 (9%)
Query: 32 VSVILAQSIDSLVDSDS--PQN-VVKFRLGCDFD--EGDDLVRIGAGLNQISAYLSVTVY 86
++ LAQ+ ++++ + PQN V+ R DF+ E D+ +SA+ V V
Sbjct: 277 ITYSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVE 336
Query: 87 IEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLTIPLTVPRGLTI-- 140
+ DVNDN P + + + E +P +F I +G +T L I
Sbjct: 337 VVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLREDLPFVIKP 396
Query: 141 -FKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ 198
F + + D+ Y+I + D G +L + +L+ V D +E
Sbjct: 397 TFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDS 456
Query: 199 LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI--SGNDRKLF---SLDSVNGSL 253
++ + + +F +HA D DLG A + Y L+ D +F S++S NG L
Sbjct: 457 YILTV--RENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKL 514
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
+ + +D +A + Q FV V+A+ ++Q V + +LD NDN P N
Sbjct: 515 YALRTMDYEAIQDFQ---FV--VKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNG 569
Query: 314 SIVEN--LPN----GFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
++ N +P G+ V +V+A D D G+N +Y L G FS+ ++G
Sbjct: 570 TLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNG 623
Score = 59.7 bits (138), Expect = 6e-07
Identities = 58/201 (28%), Positives = 93/201 (46%), Gaps = 20/201 (9%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+ + EN I K++A DLD G N QI Y +PP + D L V Y IN
Sbjct: 458 ILTVRENNSPAVFIGKVHAEDLDLGENAQITYSL-----LPPK--NGD-LSVFAYISINS 509
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+G + R++ E+ +F+ + A DGG +L+ ++VRV V D ND+ P+ N
Sbjct: 510 GNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNG 569
Query: 1053 N------VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVN 1105
V + ++ KV A D D GQN+ L+Y + + TDL F + G +
Sbjct: 570 TLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKA-TDLGLFSVQRQNGEIHTL 628
Query: 1106 GELDRETEDKYILTVVARDNG 1126
++ L ++ +D+G
Sbjct: 629 RQISERDPMMQKLIILVQDHG 649
Score = 55.2 bits (127), Expect = 1e-05
Identities = 48/174 (27%), Positives = 77/174 (44%), Gaps = 11/174 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A+D D G + Y L + K F +D NG + L LD +A T+ +
Sbjct: 264 VTAVDLDEGTNKAITYSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEA-----IETYDID 318
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+QA+ +A ++V +E++D+NDN PE V + + E+ P V D+D
Sbjct: 319 IQATDGGG--LSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDI 376
Query: 336 GENGEFTYQLDDPKGAFSIDPRSG-WLTVRNQTVLDREAHSSLRMKVYAKETNP 388
G+ T L + F I P G ++ LDRE S + + A +T P
Sbjct: 377 RVGGKVTCFLREDL-PFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGP 429
Score = 44.0 bits (99), Expect = 0.032
Identities = 40/134 (29%), Positives = 63/134 (47%), Gaps = 5/134 (3%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
++G A L+S ++ F L G LF++++LD ++ +A+ VL + L
Sbjct: 55 EVGKLAARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCG-KADPCVLHFEVV-LVE 112
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
PL++ +A E+ + D+NDN P F + I E+ P G A D D G NG Y
Sbjct: 113 PLQSFRA--EVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNY 170
Query: 344 QLDDPKGAFSIDPR 357
L G F + R
Sbjct: 171 TL-SANGYFHLHTR 183
>UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A
CG6445-PA, isoform A; n=2; Apocrita|Rep: PREDICTED:
similar to Cad74A CG6445-PA, isoform A - Apis mellifera
Length = 1843
Score = 107 bits (256), Expect = 3e-21
Identities = 124/510 (24%), Positives = 224/510 (43%), Gaps = 46/510 (9%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
+Y + MS NV V + D NDNNPVF + Y+ S+ + K ++ VKA D D
Sbjct: 1036 DYEITRKMSEANVIVEVQDTNDNNPVFAQKD-YKISVLESEKPSKIVLNVKATDMDSSNT 1094
Query: 493 GMVL---YDLQRTSNL-TITSPFKINPNTGTVSVAESPILEGRH----ALFVEASDQPAN 544
+ Y R S + + F++ P TG + +A + L+ +V ASD P
Sbjct: 1095 EQEVRRGYGEVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQG 1154
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN 604
+E+R + A+VT++V + P F Y + N G SV I D E
Sbjct: 1155 GAEQRSTRALVTVDVL----DVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDK 1210
Query: 605 D--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
++Y+++ E F ++ ++G I L+ R + ++ + ++
Sbjct: 1211 GGVINYEIIDEGEASGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDV 1270
Query: 663 --TVHVVDVNDERGV-LLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSS-IYGNGTGNVR 717
T+++ DV GV L + ++ ENS G+ + Q+ ++ NG +
Sbjct: 1271 ILTLYIGDVVSNDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFK 1330
Query: 718 FLIANQ--QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
FL +D + +E G I T+K LDRE +D Y + ++A+ + G + +
Sbjct: 1331 FLEDGNFGKDASAFRINSETGLITTRKLLDREAKDSYTLILVAQ-DLGNPPQQATRVLQV 1389
Query: 776 YIEDENDNPPVF----EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-F 830
+ D +D+ P F + E ++E + IG ++ +I+A D D G N + Y + +
Sbjct: 1390 IVNDIDDHKPHFKRNLDSPPVELAVLEETPIGAKV---GVIEAIDEDIGENGMIDYAIVY 1446
Query: 831 GEGKEMFDVD--ENTGVVKFIGDSLDREKKIMYKLSL----VARDTGGL---------SS 875
G +F V+ EN V LDRE+ + L++ + G + S
Sbjct: 1447 GNEAGLFLVERLENNSAVIRSNGRLDRERADHHLLTIKCFPYSTKKGDIVPKPYNRQDPS 1506
Query: 876 EAELIIMIGDENDNKPEFNQIEENSKVRIH 905
E ++++ + D +DN+P+F + VR++
Sbjct: 1507 ERQVLVKVLDIDDNRPKFKKENVTLGVRLN 1536
Score = 102 bits (244), Expect = 9e-20
Identities = 180/728 (24%), Positives = 289/728 (39%), Gaps = 104/728 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG---QNGMV----LY 497
V V ++D N+ P F S Y + A +G + KV A DPD + +V
Sbjct: 808 VTVNMIDVNNKPPTFNEST-YLVYVSERAAIGEPVLKVAATDPDSDAYLEYSIVEPIRAV 866
Query: 498 D-----LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA----LFVEASDQPANPSER 548
D L+ T+ + F+IN TG ++V + +L+ + A L V+ D A +
Sbjct: 867 DKTGVALKNTAPYDYKTAFRINSTTGLITV--NRVLDYQVAAVVILTVQVQDLNAVVDKE 924
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE-------FWVGSNVGIGTSVGQIRVNDAF 601
R + +EVT + D P F + V +GT++ + +
Sbjct: 925 RQ---ITRVEVTIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSAREPT 981
Query: 602 EQNDVS-YDLLH-GYEEG-VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS- 657
V ++L+ +EG V V+ + V++ D N+ F+ AL + ++
Sbjct: 982 TGYPVQRFELVREDDDEGYVNVGVQSGNVVLSKRLDYEALNQKFIQFKVRALARDYEITR 1041
Query: 658 --IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA---GAAIGQIFHTNMSSIYGNG 712
N V V D ND V + + + ++ S + +N G
Sbjct: 1042 KMSEANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNTEQEVRRG 1101
Query: 713 TGNVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEF--NKGVISGAG 769
G VR+ LI ++ + I + I T LDREK+ V R V+A G +
Sbjct: 1102 YGEVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRST 1161
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
VT+ + D NDN P FE Y I EN+ G + I ATD DE + Y +
Sbjct: 1162 RALVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVN---ITATDPDEDKGGVINYEI 1218
Query: 830 FGEGKE--MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
EG+ +F++D TG + + + Y + + D G L S+ L + IGD
Sbjct: 1219 IDEGEASGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIGD 1278
Query: 886 --ENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPEN 943
ND P F + I N T G + +V A D D N
Sbjct: 1279 VVSNDGVPLFIRPTLEEVAYISE----NSTIGSPVFQV-----VASDPDD--------PN 1321
Query: 944 IPIGTTIIKLNALDLDSGLNGQ--IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
+P G K L+ G G+ + NSE + ++ D E K + + +
Sbjct: 1322 LPNGKITFKF----LEDGNFGKDASAFRINSETGLITTRKLLDR-EAKDSYTL------I 1370
Query: 1002 IVARSL--PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+VA+ L PP+ R+ ++V V D++DH P FK+ + VE A
Sbjct: 1371 LVAQDLGNPPQQATRV---------------LQVIVNDIDDHKPHFKRNLDSPPVELAVL 1415
Query: 1060 TRRVLGK----VDATDADFGQNANLTYFIQPSDTDLPFEISPL---TGVLSVNGELDRET 1112
+G ++A D D G+N + Y I + F + L + V+ NG LDRE
Sbjct: 1416 EETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLVERLENNSAVIRSNGRLDRER 1475
Query: 1113 EDKYILTV 1120
D ++LT+
Sbjct: 1476 ADHHLLTI 1483
Score = 83.8 bits (198), Expect = 3e-14
Identities = 176/733 (24%), Positives = 310/733 (42%), Gaps = 83/733 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + L+Y + SG + F +DS +G + + + LD E + + V A
Sbjct: 739 ANDPD-GRDSLLQYHIASGA-KDNFVIDSSSGVITVSPDARLDLESG--GEKYEVIVYAI 794
Query: 280 QLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P++ TA V + ++D+N+ P F Y + + E G VL+V ATD D +
Sbjct: 795 DSGTPVRETATTTVTVNMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPDS--D 852
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQ 398
Y + +P A +D ++G + ++N D + ++ R+ T V D Q
Sbjct: 853 AYLEYSIVEPIRA--VD-KTG-VALKNTAPYDYK--TAFRIN---STTGLITVNRVLDYQ 903
Query: 399 --RIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+ Q + NA ++K + +V T I+ Y + +F N + NN
Sbjct: 904 VAAVVILTVQVQDLNAVVDKERQITRVEV---TIYIQAYSDDNPTFTNP-----GWSPNN 955
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P S+ +GT + + A +P G + ++L R + +
Sbjct: 956 PTI------RISVPEEQPLGTTLLMLSAREPTTGYP-VQRFELVREDD--DEGYVNVGVQ 1006
Query: 517 TGTVSVAESPILEGRHALFVEASDQP-ANPSE--RRYSLAVVTIEVTRGTKGNKPDIP-- 571
+G V +++ E + F++ + A E R+ S A V +EV + T N P
Sbjct: 1007 SGNVVLSKRLDYEALNQKFIQFKVRALARDYEITRKMSEANVIVEV-QDTNDNNPVFAQK 1065
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-----NDVSYDLLHGYEEGVPFAVEERS 626
D+ + E S + + + ++ ++ +V Y L+ E F VE +
Sbjct: 1066 DYKISVLESEKPSKIVLNVKATDMDSSNTEQEVRRGYGEVRYSLIG--ENANMFEVEPIT 1123
Query: 627 GVITVVDD--LSRYNRPMYDFEAVA--LQENANLSIVTNA--TVHVVDVNDERGVLLKGA 680
G I + + L R + + F VA + + T A TV V+DVND + A
Sbjct: 1124 GNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRSTRALVTVDVLDVNDNAPTFEQEA 1183
Query: 681 HSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-EDGTI 738
++ +I EN+ +G ++ I T+ G G + + I ++ + + I + G I
Sbjct: 1184 YTAVI---PENAPSGVSVVNITATDPDEDKG---GVINYEIIDEGEASGLFEIDHKTGEI 1237
Query: 739 FTQKPLDREKR-DVYRMTVIAEFNKGVISGAGIYQVTIYIED--ENDNPPVFEHATYE-- 793
++ + L + R + Y M + E + G +T+YI D ND P+F T E
Sbjct: 1238 YSARALTGKGRTEPYIMRIRGE-DGGEPELYSDVILTLYIGDVVSNDGVPLFIRPTLEEV 1296
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTL-----FGEGKEMFDVDENTGVV 846
+I ENS IG+ + + A+D D+ N + FG+ F ++ TG++
Sbjct: 1297 AYISENSTIGSPVFQ---VVASDPDDPNLPNGKITFKFLEDGNFGKDASAFRINSETGLI 1353
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAE--LIIMIGDENDNKPEFNQIEENSKVR- 903
LDRE K Y L LVA+D G +A L +++ D +D+KP F + ++ V
Sbjct: 1354 T-TRKLLDREAKDSYTLILVAQDLGNPPQQATRVLQVIVNDIDDHKPHFKRNLDSPPVEL 1412
Query: 904 -IHRETKLNGTAG 915
+ ET + G
Sbjct: 1413 AVLEETPIGAKVG 1425
Score = 77.0 bits (181), Expect = 4e-12
Identities = 127/499 (25%), Positives = 209/499 (41%), Gaps = 66/499 (13%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L + V V +LD D PVF+ + Y ++ N G I V+A D D G+ +L
Sbjct: 231 RLQARATVAVDVLDVQDQPPVFLNAP-YSAALPENTAAGHTILTVRARDGDTGEPRSLLL 289
Query: 498 DL--QRTSNLTITSPFKINPNTG---TVSVA---ESP-ILE--GRHALFVEASDQPANPS 546
L + + + + + + G T +V+ E P IL+ G + V+A++ N
Sbjct: 290 TLEDEDSGHFDLDVSREGDATVGKLVTTNVSLDREDPRILQNGGIYTFQVKATELINNEI 349
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIR--VNDAFEQ 603
+ ++VTI VT + D+ P F + + ++G T + + V+D
Sbjct: 350 PAETATSIVTIVVT-----DVDDLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVG 404
Query: 604 NDVSYDLLHGYEEGVP-----FAV--EERSGVITVV----------DDLSRYNRPMYDFE 646
+ Y L + G P F V EE G + VV D+ R +FE
Sbjct: 405 ENAKYTLALRDDPGYPGISRAFVVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQLEFE 464
Query: 647 AVALQENANLSIVTNATVHV--VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
VAL N +V ++ VHV D ND + + + ++ G G +F +
Sbjct: 465 VVALVAN---QVVASSRVHVRLKDANDHSPEFSQSVYK--LSLPEDAGIGTRFGDVFARD 519
Query: 705 M-SSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKG 763
S +G T +R A++ + G I K LD E + Y +T+ A+ G
Sbjct: 520 YDSGSFGELTYTLRGFGADKFATN-----PKTGGISVSKALDYEAQKSYSLTMEAKDGGG 574
Query: 764 VISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD---EG 820
+S I I +ED NDN P FE Y + E + T ++ATDAD +G
Sbjct: 575 RVSAVNI---LIELEDVNDNKPAFEQKEYTRTVREGA---TSFDPQMFVRATDADGPMQG 628
Query: 821 TNALFMYTLFGEG---KEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTG--GLS 874
N Y++ ++F ++ +TG V D ++ +Y+L++ A D G L
Sbjct: 629 -NGKVTYSISSHNSMTNDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLF 687
Query: 875 SEAELIIMIGDENDNKPEF 893
SE L + +G + KP F
Sbjct: 688 SETRLSVRVGVPGNQKPIF 706
Score = 77.0 bits (181), Expect = 4e-12
Identities = 45/132 (34%), Positives = 69/132 (52%), Gaps = 4/132 (3%)
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+V + ++D ND+ P F + Y+ + E++ IGT + A D D G+ YTL G
Sbjct: 478 RVHVRLKDANDHSPEFSQSVYKLSLPEDAGIGTRF---GDVFARDYDSGSFGELTYTLRG 534
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
G + F + TG + + +LD E + Y L++ A+D GG S ++I + D NDNKP
Sbjct: 535 FGADKFATNPKTGGIS-VSKALDYEAQKSYSLTMEAKDGGGRVSAVNILIELEDVNDNKP 593
Query: 892 EFNQIEENSKVR 903
F Q E VR
Sbjct: 594 AFEQKEYTRTVR 605
Score = 75.8 bits (178), Expect = 9e-12
Identities = 160/723 (22%), Positives = 293/723 (40%), Gaps = 92/723 (12%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGN-DRKLFSLDSVNGS----------LFLEKELDLDA 263
P I D+D GV A + E +S + D + + +V+ + L K LD +
Sbjct: 152 PGTITITDRDGGVNADVHVECVSASRDDDVCDVFNVSTEKLAEGKYDVQISLAKSLDYER 211
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
++ N + AS ++ L+ A+A V +++LD+ D P F Y+ ++ EN G
Sbjct: 212 RNSYLINLLAID-GASDVSRRLQ-ARATVAVDVLDVQDQPPVFLNAPYSAALPENTAAGH 269
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
++L V A D D G +PRS LT+ ++ H L +
Sbjct: 270 TILTVRARDGDTG------------------EPRSLLLTLEDED----SGHFDLDVSREG 307
Query: 384 KETNPSVVGTFADSQRIAKWRRQP-LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSF 442
T +V T ++ R P + N + Y F K T+ N E E S
Sbjct: 308 DATVGKLVTT-----NVSLDREDPRILQNGGI----YTFQVKA-TELINNEIPAETATSI 357
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV--DPDLGQNGMVLYDLQ 500
V + VT D +D PVF + ++ + T + + + D D+G+N L+
Sbjct: 358 VTIVVT--DVDDLMPVF-NQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALR 414
Query: 501 RTSNLT-ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSL-AVVTIE 558
I+ F + P V +++ R+ ++ + + + + A+V +
Sbjct: 415 DDPGYPGISRAFVVGPEEAQGRVPV--VVKARNVSVLDYDVEDIARRQLEFEVVALVANQ 472
Query: 559 VTRGT------KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDL 610
V + K P+F + Y+ + + GIGT G + R D+ +++Y
Sbjct: 473 VVASSRVHVRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTY-T 531
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
L G+ FA ++G I+V L + Y A +S V N + + DVN
Sbjct: 532 LRGFGAD-KFATNPKTGGISVSKALDYEAQKSYSLTMEAKDGGGRVSAV-NILIELEDVN 589
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + + ++ V+E + + G G V + I++ +T+D+
Sbjct: 590 DNKPAFEQKEYTRT---VREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDV 646
Query: 731 -AIAED-GTIFTQKPL--DREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
I D G + K + D +R +Y + + A + G ++++ + + P+
Sbjct: 647 FKINRDTGEVTMAKAVRSDDTERGIYELAIRAT-DAGTPPLFSETRLSVRVGVPGNQKPI 705
Query: 787 FE---------HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF 837
F +TY ++EN+ GTE+ + A D D G ++L Y + K+ F
Sbjct: 706 FRGNYKSNLPGPSTYRARLLENASPGTEVIR---VVANDPD-GRDSLLQYHIASGAKDNF 761
Query: 838 DVDENTGVVKFIGDS-LDREK-KIMYKLSLVARDTGGLSSE---AELIIMIGDENDNKPE 892
+D ++GV+ D+ LD E Y++ + A D+G E + + + D N+ P
Sbjct: 762 VIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTVNMIDVNNKPPT 821
Query: 893 FNQ 895
FN+
Sbjct: 822 FNE 824
Score = 72.9 bits (171), Expect = 6e-11
Identities = 156/659 (23%), Positives = 262/659 (39%), Gaps = 93/659 (14%)
Query: 728 DDIAIAEDGTIFTQKP---LDREKR-DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D+ I + T P LD E + Y + V A + + VT+ + D N+
Sbjct: 759 DNFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTVNMIDVNNK 818
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
PP F +TY ++ E + IG + ++K D ++A Y++ E + T
Sbjct: 819 PPTFNESTYLVYVSERAAIG-----EPVLKVAATDPDSDAYLEYSIV----EPIRAVDKT 869
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGGL-----------SSEAELIIMIGDENDNKPE 892
GV +L YK + T GL ++ L + + D N +
Sbjct: 870 GV------ALKNTAPYDYKTAFRINSTTGLITVNRVLDYQVAAVVILTVQVQDLNAVVDK 923
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
QI +V I+ + + FT P N + + +PE P+GTT++
Sbjct: 924 ERQITR-VEVTIYIQAYSDDNPTFTNPGWSPNNP-TIRIS-------VPEEQPLGTTLLM 974
Query: 953 LNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKR--YFVINERHGHVIVARS 1006
L+A + +G Q R+E + E Y+ S + + KR Y +N++ V R+
Sbjct: 975 LSAREPTTGYPVQ-RFELVREDDDEGYVNVGVQSGNVVLSKRLDYEALNQKFIQFKV-RA 1032
Query: 1007 LPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
L + E +S +V V V+D ND+ PVF + Y +V E++ +++
Sbjct: 1033 LARDYEITRKMS---------EANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLN 1083
Query: 1067 VDATDADFGQN--------ANLTYFIQPSDTDLPFEISPLTGVLSV--NGELDRETEDKY 1116
V ATD D + Y + + ++ FE+ P+TG + + N LDRE +
Sbjct: 1084 VKATDMDSSNTEQEVRRGYGEVRYSLIGENANM-FEVEPITGNIQIATNTTLDREKQSVL 1142
Query: 1117 ILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHPEADELSNHN 1172
VVA D G DVNDN+P F A+ ++ P + N
Sbjct: 1143 RFYVVASDMPQGGAEQRSTRALVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNIT 1202
Query: 1173 F----ESVMMIPVYKATIEENA----PIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
E + Y+ E A I ++++ G G R
Sbjct: 1203 ATDPDEDKGGVINYEIIDEGEASGLFEIDHKTGEIYSARA-LTGKGR---TEPYIMRIRG 1258
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE--LEIEEN--VNAPV-ELVSL 1279
++ G P L S IL + + DV V P+FI E I EN + +PV ++V+
Sbjct: 1259 EDGGEPELYSDVILTLYIGDV---VSNDGVPLFIRPTLEEVAYISENSTIGSPVFQVVAS 1315
Query: 1280 NLTE-HYENFKMRYYILNE-NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ + + N K+ + L + N F I+ G + + DRE KD+Y +I+ A+
Sbjct: 1316 DPDDPNLPNGKITFKFLEDGNFGKDASAFRINSETGLITTRKLLDREAKDSYTLILVAQ 1374
Score = 72.1 bits (169), Expect = 1e-10
Identities = 178/806 (22%), Positives = 307/806 (38%), Gaps = 133/806 (16%)
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE 524
Y + NA GT + +V A DPD G++ ++ Y + + F I+ ++G ++V+
Sbjct: 720 YRARLLENASPGTEVIRVVANDPD-GRDSLLQYHIASGAK----DNFVIDSSSGVITVSP 774
Query: 525 SPILE-----GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE 579
L+ ++ + V A D E A T+ V NKP P F + Y
Sbjct: 775 DARLDLESGGEKYEVIVYAIDSGTPVRET----ATTTVTVNMIDVNNKP--PTFNESTYL 828
Query: 580 FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG----------------YEEGVPFAVE 623
+V IG V ++ D + Y ++ Y+ F +
Sbjct: 829 VYVSERAAIGEPVLKVAATDPDSDAYLEYSIVEPIRAVDKTGVALKNTAPYDYKTAFRIN 888
Query: 624 ERSGVITV-------VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
+G+ITV V + + D AV +E + T+++ +D+
Sbjct: 889 STTGLITVNRVLDYQVAAVVILTVQVQDLNAVVDKERQITRV--EVTIYIQAYSDDNPTF 946
Query: 677 LKGAHSP----IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
SP I V E +G + G RF + + D + +
Sbjct: 947 TNPGWSPNNPTIRISVPEEQP---LGTTLLMLSAREPTTGYPVQRFELVREDDDEGYVNV 1003
Query: 733 A-EDGTIFTQKPLDRE----KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ G + K LD E K +++ +A + + V + ++D NDN PVF
Sbjct: 1004 GVQSGNVVLSKRLDYEALNQKFIQFKVRALAR-DYEITRKMSEANVIVEVQDTNDNNPVF 1062
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
Y+ ++E+ K ++I ++ +KATD D + +GE + + EN + +
Sbjct: 1063 AQKDYKISVLESEK-PSKIVLN--VKATDMDSSNTEQEVRRGYGEVRYSL-IGENANMFE 1118
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+ I + + T L E + ++ + P+ E+ S
Sbjct: 1119 V--------EPITGNIQIATNTT--LDREKQSVLRFYVVASDMPQ-GGAEQRS------- 1160
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
T ++V N A +Q +IPEN P G +++ + A D D G I
Sbjct: 1161 -----TRALVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVIN 1215
Query: 968 YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE---FRLNISALDGG- 1023
YE D E F I+ + G + AR+L + + + I DGG
Sbjct: 1216 YEI------------IDEGEASGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGE 1263
Query: 1024 -NLNDNISVRVFVKDV--NDHFPVFKKTWYN--FNVEEAQYTRRVLGKVDATDADFGQ-- 1076
L ++ + +++ DV ND P+F + + E + +V A+D D
Sbjct: 1264 PELYSDVILTLYIGDVVSNDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLP 1323
Query: 1077 NANLTY-FIQPSD---TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
N +T+ F++ + F I+ TG+++ LDRE +D Y L +VA+D G
Sbjct: 1324 NGKITFKFLEDGNFGKDASAFRINSETGLITTRKLLDREAKDSYTLILVAQDLG-NPPQQ 1382
Query: 1133 XXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPI 1192
D++D+ P F N +S PV A +EE PI
Sbjct: 1383 ATRVLQVIVNDIDDHKPHF------------------KRNLDSP---PVELAVLEE-TPI 1420
Query: 1193 GTTVAKVFANDTDFIGNGNGLILYSL 1218
G V + A D D IG NG+I Y++
Sbjct: 1421 GAKVGVIEAIDED-IGE-NGMIDYAI 1444
Score = 69.3 bits (162), Expect = 8e-10
Identities = 83/347 (23%), Positives = 134/347 (38%), Gaps = 36/347 (10%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+ + AL + + V V +KD NDH P F ++ Y ++ E G V A D
Sbjct: 460 QLEFEVVALVANQVVASSRVHVRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARD 519
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXX 1131
D G LTY ++ D F +P TG +SV+ LD E + Y LT+ A+D G
Sbjct: 520 YDSGSFGELTYTLRGFGAD-KFATNPKTGGISVSKALDYEAQKSYSLTMEAKDGG---GR 575
Query: 1132 XXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP 1191
DVNDN P F E E+ + ++ + + + ++ N
Sbjct: 576 VSAVNILIELEDVNDNKPAF----EQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGK 631
Query: 1192 IGTTVA--KVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTA-------ILMVTV 1242
+ +++ ND I G + + R + G+ L+ A + T
Sbjct: 632 VTYSISSHNSMTNDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETR 691
Query: 1243 ADVPDEVEMSDKPVFISRY---------YELEIEENVNAPVELVSLNLTEHYENFKMRYY 1293
V V + KP+F Y Y + EN + E++ + + + Y
Sbjct: 692 LSVRVGVPGNQKPIFRGNYKSNLPGPSTYRARLLENASPGTEVIRVVANDPDGRDSLLQY 751
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK-----DTYEVIVRA 1335
+ D FVID +G + + SPD + + YEVIV A
Sbjct: 752 HIASGAKD---NFVIDSSSGVITV--SPDARLDLESGGEKYEVIVYA 793
Score = 59.3 bits (137), Expect = 8e-07
Identities = 73/294 (24%), Positives = 120/294 (40%), Gaps = 38/294 (12%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+ +K N + + Q +PE+ IGT + A D DSG G++ Y
Sbjct: 481 VRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTYTLRG------ 534
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK 1036
AD F N + G + V+++L E++ + L + A DGG +++ + ++
Sbjct: 535 --FGADK------FATNPKTGGISVSKALDYEAQKSYSLTMEAKDGGGRVSAVNILIELE 586
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD--FGQNANLTYFIQP--SDTDLP 1092
DVND+ P F++ Y V E + V ATDAD N +TY I S T+
Sbjct: 587 DVNDNKPAFEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDV 646
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F+I+ TG +++ + + ++ I + R V N +
Sbjct: 647 FKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRVGVPGNQKPIF 706
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIP-VYKATIEENAPIGTTVAKVFANDTD 1205
N++S + P Y+A + ENA GT V +V AND D
Sbjct: 707 -----------------RGNYKSNLPGPSTYRARLLENASPGTEVIRVVANDPD 743
Score = 53.2 bits (122), Expect = 5e-05
Identities = 42/158 (26%), Positives = 76/158 (48%), Gaps = 14/158 (8%)
Query: 238 GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
G D F ++S G + K LD +A+ +++ L + A L NP + A +++ +
Sbjct: 1338 GKDASAFRINSETGLITTRKLLDREAK-----DSYTLILVAQDLGNPPQQATRVLQVIVN 1392
Query: 298 DLNDNLPEFEVDF----YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGA 351
D++D+ P F+ + ++++E P G V + A D+D GENG Y + + G
Sbjct: 1393 DIDDHKPHFKRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGL 1452
Query: 352 FSIDP-RSGWLTVRNQTVLDREA--HSSLRMKVYAKET 386
F ++ + +R+ LDRE H L +K + T
Sbjct: 1453 FLVERLENNSAVIRSNGRLDRERADHHLLTIKCFPYST 1490
Score = 52.8 bits (121), Expect = 7e-05
Identities = 57/232 (24%), Positives = 98/232 (42%), Gaps = 28/232 (12%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE----DENDNPPVFEH 789
+ G + +K LDRE +D+ + +I+ ++G I+G+ V++ E DENDNPPV+
Sbjct: 75 DSGVVVLRKALDRESQDLIEV-IISITDEG-IAGSEPNTVSLRREIAVLDENDNPPVYHG 132
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
Y + E++ +G + I TD D G NA DV V+ +
Sbjct: 133 RPYAARVPESAHVGGLLVPPGTITITDRDGGVNA--------------DVH-----VECV 173
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
S D + ++ +S G + L + E N N + + + R +
Sbjct: 174 SASRDDDVCDVFNVSTEKLAEGKYDVQISLAKSLDYERRNSYLINLLAIDGASDVSRRLQ 233
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
T +++V+ + L+ L PEN G TI+ + A D D+G
Sbjct: 234 ARATVAVDVLDVQDQPPVFLNAPYSAAL---PENTAAGHTILTVRARDGDTG 282
Score = 49.6 bits (113), Expect = 6e-04
Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 9/126 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSV-NGSLFLEKELDLDAE----HNLQANTF 272
I AID+D+G + Y ++ GN+ LF ++ + N S + LD E H L F
Sbjct: 1427 IEAIDEDIGENGMIDYAIVYGNEAGLFLVERLENNSAVIRSNGRLDRERADHHLLTIKCF 1486
Query: 273 VLQVQASQL----NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ + N ++ +V +++LD++DN P+F+ + + + N+P S++ +
Sbjct: 1487 PYSTKKGDIVPKPYNRQDPSERQVLVKVLDIDDNRPKFKKENVTLGVRLNVPIDTSLITL 1546
Query: 329 MATDKD 334
A D D
Sbjct: 1547 EALDAD 1552
Score = 47.2 bits (107), Expect = 0.003
Identities = 56/199 (28%), Positives = 85/199 (42%), Gaps = 24/199 (12%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE--DENDNPPVFEHATY 792
D I K LD E+R+ Y + ++A +S + T+ ++ D D PPVF +A Y
Sbjct: 198 DVQISLAKSLDYERRNSYLINLLAIDGASDVSRRLQARATVAVDVLDVQDQPPVFLNAPY 257
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV------DENTGVV 846
+ EN+ G I ++A D D G + TL E FD+ D G +
Sbjct: 258 SAALPENTAAGHTIL---TVRARDGDTGEPRSLLLTLEDEDSGHFDLDVSREGDATVGKL 314
Query: 847 KFIGDSLDRE-KKIM-----YKLSLVARDTGGLSSEAE-----LIIMIGDENDNKPEFNQ 895
SLDRE +I+ Y + A + AE + I++ D +D P FNQ
Sbjct: 315 VTTNVSLDREDPRILQNGGIYTFQVKATELINNEIPAETATSIVTIVVTDVDDLMPVFNQ 374
Query: 896 IEENSKVR--IHRETKLNG 912
N + I ++T L G
Sbjct: 375 KYFNITISEDIGKDTPLPG 393
Score = 45.2 bits (102), Expect = 0.014
Identities = 59/223 (26%), Positives = 101/223 (45%), Gaps = 30/223 (13%)
Query: 1187 EENAPIG---TTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
E +A +G TT + D + NG G+ + + + N +P+ ++T+I+ + V
Sbjct: 306 EGDATVGKLVTTNVSLDREDPRILQNG-GIYTFQVKATELINN-EIPAETATSIVTIVVT 363
Query: 1244 DVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT----EHYENFKMRYYILNEND 1299
DV D + PVF +Y+ + I E++ L LN+ + EN K + ++
Sbjct: 364 DVDDLM-----PVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALRDDPG 418
Query: 1300 -TDIRRTFVIDPRNG---TLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDV 1355
I R FV+ P +V++ + V D Y+V A RQ ++ VA V
Sbjct: 419 YPGISRAFVVGPEEAQGRVPVVVKARNVSVLD-YDVEDIARRQLEFE----VVALVANQV 473
Query: 1356 LEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG 1398
+ +V VR+KD ND+SP+F+ L ++P A G
Sbjct: 474 VASS-----RVHVRLKDANDHSPEFSQSVYKL--SLPEDAGIG 509
Score = 38.3 bits (85), Expect = 1.6
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 10/100 (10%)
Query: 991 YFVINERHGHVIVARSLPPESE--FRLNISALD---GGNLNDNISVR--VFVKDVNDHFP 1043
YF +N G V++ ++L ES+ + IS D G+ + +S+R + V D ND+ P
Sbjct: 69 YFTVNRDSGVVVLRKALDRESQDLIEVIISITDEGIAGSEPNTVSLRREIAVLDENDNPP 128
Query: 1044 VFKKTWYNFNVEEAQYTRRVL---GKVDATDADFGQNANL 1080
V+ Y V E+ + +L G + TD D G NA++
Sbjct: 129 VYHGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADV 168
Score = 38.3 bits (85), Expect = 1.6
Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 26/192 (13%)
Query: 940 IPENIPIGTTIIK---LNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYF 992
+PE+ +G ++ + D D G+N + E S + +S + L +Y
Sbjct: 139 VPESAHVGGLLVPPGTITITDRDGGVNADVHVECVSASRDDDVCDVFNVSTEKLAEGKYD 198
Query: 993 VINERHGHVIVARSLPPE--SEFRLNISALDGGN-----LNDNISVRVFVKDVNDHFPVF 1045
V + +A+SL E + + +N+ A+DG + L +V V V DV D PVF
Sbjct: 199 V------QISLAKSLDYERRNSYLINLLAIDGASDVSRRLQARATVAVDVLDVQDQPPVF 252
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT-----DLPFEISPLTG 1100
Y+ + E + V A D D G+ +L ++ D+ D+ E G
Sbjct: 253 LNAPYSAALPENTAAGHTILTVRARDGDTGEPRSLLLTLEDEDSGHFDLDVSREGDATVG 312
Query: 1101 -VLSVNGELDRE 1111
+++ N LDRE
Sbjct: 313 KLVTTNVSLDRE 324
Score = 36.7 bits (81), Expect = 4.9
Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI---GKVKAVDPDLGQNGMVLYD-LQR 501
E+ +LD NDN PV+ Y + +A VG ++ G + D D G N V + +
Sbjct: 117 EIAVLDENDNPPVY-HGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADVHVECVSA 175
Query: 502 TSNLTITSPFKINPN-------TGTVSVAESPILEGRHALFVE--ASDQPANPSERRYSL 552
+ + + F ++ +S+A+S E R++ + A D ++ S R +
Sbjct: 176 SRDDDVCDVFNVSTEKLAEGKYDVQISLAKSLDYERRNSYLINLLAIDGASDVSRRLQAR 235
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
A V ++V ++P P F+ APY + N G ++ +R D
Sbjct: 236 ATVAVDVL--DVQDQP--PVFLNAPYSAALPENTAAGHTILTVRARD 278
Score = 36.3 bits (80), Expect = 6.5
Identities = 49/180 (27%), Positives = 77/180 (42%), Gaps = 24/180 (13%)
Query: 992 FVINERHGHVIVARSLPPESE----FRLNISALDGGN----LNDNISVRVFVKDVNDHFP 1043
F IN G V +A+++ + + L I A D G +SVRV V + P
Sbjct: 647 FKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRVGVP--GNQKP 704
Query: 1044 VFKKTWYNFNVEEAQYTRRVLG---------KVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+F+ + + + Y R+L +V A D D G+++ L Y I D F
Sbjct: 705 IFRGNYKSNLPGPSTYRARLLENASPGTEVIRVVANDPD-GRDSLLQYHIASGAKD-NFV 762
Query: 1095 ISPLTGVLSVNGE--LDRETE-DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
I +GV++V+ + LD E+ +KY + V A D+G DVN+ P F
Sbjct: 763 IDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTVNMIDVNNKPPTF 822
>UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
SCAF13750, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2845
Score = 107 bits (256), Expect = 3e-21
Identities = 116/457 (25%), Positives = 205/457 (44%), Gaps = 34/457 (7%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+N+ V + D NDN PV Y ++K NA GT + V A DPD G N + Y L+
Sbjct: 1991 LNITVIVSDINDNPPV-CDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSK 2049
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+ PF ++ TG ++V E + + + V A+D+ + S + VV +E
Sbjct: 2050 LRGIHSDPFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADK-GSVSLSTHCNVVVRVE-- 2106
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P+I + + GT V + V D + V+ ++ +PF
Sbjct: 2107 -DVNDNPPEIEI---TSLSSSIPEDAPPGTVVALMGVTD--RDSGVNGQVICSVPAHLPF 2160
Query: 621 ----AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERG 674
+ + S + D L + + MYD + A ++ + ++ + +H V+DVND R
Sbjct: 2161 DLKPSPDGHSYSLVTKDYLDKESTHMYDIQITA-KDLGSPALSSTKVIHVDVLDVNDNRP 2219
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ-DVTDDIAI 732
+ + SP F+V EN+ AG+++ + +++ S G LI NQ +T + I
Sbjct: 2220 LF---SESPYTFYVPENNKAGSSVFTVSASDVDS--GQNAALSYSLIRNQDLTITSFLNI 2274
Query: 733 AE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
E +GTI K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 2275 NEANGTISALKTFDFETLKTFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILYPV 2333
Query: 792 YEGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVV 846
E +I + ++ ++A DAD G N ++ L +F +D TG +
Sbjct: 2334 SSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQI 2393
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ + S + +KL ++ +D G +S A +++
Sbjct: 2394 RTL-RSFTETDEAEHKLVILVKDNGNVSLSATATVLV 2429
Score = 96.7 bits (230), Expect = 4e-18
Identities = 127/513 (24%), Positives = 215/513 (41%), Gaps = 63/513 (12%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
IIE+ N A + + E+ +G+ A DL+ G+N Y+ N+ Y
Sbjct: 1885 IIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINNNQYF- 1943
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
+E + F + + +I+ R L E ++ L ++ALDGG + N+++ V
Sbjct: 1944 -------RVETEE-FGEDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITV 1995
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-- 1091
V D+ND+ PV K Y V+E L V+A+D D G N+ + Y ++ +
Sbjct: 1996 IVSDINDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHS 2055
Query: 1092 -PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP- 1149
PF + TG L+V LD E + Y + V+A D G DVNDN P
Sbjct: 2056 DPFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADKG-SVSLSTHCNVVVRVEDVNDNPPE 2114
Query: 1150 -KFYAFDELLEWKHPE---------ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV 1199
+ + + P D S N + + +P + + +P G + + V
Sbjct: 2115 IEITSLSSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAHLPFDLKPSPDGHSYSLV 2174
Query: 1200 FANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFIS 1259
D++ + +Y + + ++LG P+LSST ++ V V DV D ++P+F
Sbjct: 2175 ---TKDYL-DKESTHMYDI--QITAKDLGSPALSSTKVIHVDVLDVND-----NRPLFSE 2223
Query: 1260 RYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYL 1317
Y + EN + V VS + + +N + Y ++ D I I+ NGT+
Sbjct: 2224 SPYTFYVPENNKAGSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISA 2283
Query: 1318 VRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNS 1377
+++ D E T++ V VA D +V V V I D NDN+
Sbjct: 2284 LKTFDFETLKTFQFQV-----------------VASDSGSPSLSSNVTVKVFILDQNDNA 2326
Query: 1378 PKF-----TNGNRPLVTAIPTTAPFGYQVMQLK 1405
P +NG+ + IP G+ V +++
Sbjct: 2327 PVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 2359
Score = 96.3 bits (229), Expect = 6e-18
Identities = 120/519 (23%), Positives = 213/519 (41%), Gaps = 42/519 (8%)
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK 483
K+ N++ E + V + +LD NDN P F P Y + +A VG+
Sbjct: 1863 KMAPCVANLKAVVENPLEMHQVIIEILDVNDNAPKF-PEENYTLEVLESAMVGSRFQIEG 1921
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTI-TSPFKINPNTGTVSVAESPILE--GRHALFVEASD 540
A D ++G N + Y + + T F + + + E +H L V A D
Sbjct: 1922 AHDLEVGINSLQTYKINNNQYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVTALD 1981
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
++ V+ ++ + P + D Y V N GT + + +D
Sbjct: 1982 GGKPIKSGNLNITVIVSDIN-----DNPPVCDKQ--KYVVTVKENAPEGTFLLTVNASDP 2034
Query: 601 FE--QNDVSYDL---LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA- 654
E + + Y L L G PF ++ +G +TV L + +Y+ + +A + +
Sbjct: 2035 DEGMNSAIEYSLRSKLRGIHSD-PFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSV 2093
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+LS N V V DVND + + S I ++ G + + T+ S G
Sbjct: 2094 SLSTHCNVVVRVEDVNDNPPEIEITSLSSSI--PEDAPPGTVVALMGVTDRDS----GV- 2146
Query: 715 NVRFLIANQQDVTDDIAIAEDG---TIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGI 770
N + + + + D+ + DG ++ T+ LD+E +Y + + A + +S +
Sbjct: 2147 NGQVICSVPAHLPFDLKPSPDGHSYSLVTKDYLDKESTHMYDIQITAKDLGSPALSSTKV 2206
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
V + D NDN P+F + Y ++ EN+K G+ + + A+D D G NA Y+L
Sbjct: 2207 IHVDVL--DVNDNRPLFSESPYTFYVPENNKAGSSVFT---VSASDVDSGQNAALSYSLI 2261
Query: 831 GEGK----EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIG 884
+++E G + + + D E ++ +VA D+G LSS + + I
Sbjct: 2262 RNQDLTITSFLNINEANGTISAL-KTFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFIL 2320
Query: 885 DENDNKPE-FNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
D+NDN P + N E N AG + +V+
Sbjct: 2321 DQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 2359
Score = 90.6 bits (215), Expect = 3e-16
Identities = 65/245 (26%), Positives = 127/245 (51%), Gaps = 22/245 (8%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FL 719
N V + D+ND +G H+ + S +++G+ F N ++ G+ +V+ +
Sbjct: 1118 NIEVEITDINDNAPHFRRGT-----MHL-DISESSSVGERFSLNNAADPDVGSNSVKDYH 1171
Query: 720 IANQQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
++ + + +I DGT F K LDRE + V+ + ++ + GV + G + +
Sbjct: 1172 LSASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNL-ILTAVDGGVPTRTGTASIVV 1230
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA--LFMYTLFGEG 833
+ D NDN P F+ Y +MENS IG+ + + ATD DEG+N+ ++ Y+L+
Sbjct: 1231 RVLDVNDNAPSFDREKYVVDVMENSPIGSLVLK---LNATDLDEGSNSDIVYSYSLYTSE 1287
Query: 834 K--EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN 889
+ ++F ++ G ++ + + ++ E ++++ ++A D G LS + +L I + D NDN
Sbjct: 1288 RTQQVFHLNPENGEIR-VREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDN 1346
Query: 890 KPEFN 894
PE +
Sbjct: 1347 HPEIS 1351
Score = 82.2 bits (194), Expect = 1e-13
Identities = 111/472 (23%), Positives = 190/472 (40%), Gaps = 36/472 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + N+EV + D NDN P F ++ + ++ VG A DPD+G N +
Sbjct: 1111 ENPVRMFNIEVEITDINDNAPHFRRGTMH-LDISESSSVGERFSLNNAADPDVGSNSVKD 1169
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + + +I + + + ++ H L + A D S+
Sbjct: 1170 YHLSASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIV 1229
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV--SYD 609
V ++V + P F Y V N IG+ V ++ D E +D+ SY
Sbjct: 1230 VRVLDVN-------DNAPSFDREKYVVDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYS 1282
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL-SIVTNATVHVVD 668
L F + +G I V + ++ + +++ E +A + NL S T+ V D
Sbjct: 1283 LYTSERTQQVFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTD 1342
Query: 669 VNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ND + +K SP VKEN + I ++S G V I ++
Sbjct: 1343 MNDNHPEISIKSFQSP----VKENIDVETV--IAVVSVSDKDSGDNGVVDLHIPDKMPFK 1396
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ + +PLDREK Y +T ++G + +T+ + D NDN P F
Sbjct: 1397 LRQSSDNYYELVVSEPLDREKVPEYDITFTVT-DRGSPPLSDNETMTLELLDVNDNVPRF 1455
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDE 841
+ Y + EN+ G + + A D D N +Y + + +F ++
Sbjct: 1456 PQSFYTIRVTENNAPGALLSS---LTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINP 1512
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
G + + + D E + + + ARD+G LSS + I+I D+NDN P
Sbjct: 1513 ENGNLYAL-KTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAP 1563
Score = 78.6 bits (185), Expect = 1e-12
Identities = 86/331 (25%), Positives = 146/331 (44%), Gaps = 28/331 (8%)
Query: 588 IGTSVGQIRVN---DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
+G++VG I + D D + LL G ++ + F V GV++V + R
Sbjct: 1806 VGSAVGNIAKDLGLDVGRLTDRNLRLLSGTKQDL-FKVNPSDGVLSVKRRVDREELCAKM 1864
Query: 645 FEAVALQENA--NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
VA + N + + ++DVND K V E+ A +G F
Sbjct: 1865 APCVANLKAVVENPLEMHQVIIEILDVNDNAP---KFPEENYTLEVLES---AMVGSRFQ 1918
Query: 703 TNMSSIYGNGTGNVR-FLIANQQDV-TDDIAIAEDGTI---FTQKPLDREKRDVYRMTVI 757
+ G +++ + I N Q + EDG + + LDRE+ + + V
Sbjct: 1919 IEGAHDLEVGINSLQTYKINNNQYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVT 1978
Query: 758 AEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
A + G +G +T+ + D NDNPPV + Y + EN+ GT + + A+D
Sbjct: 1979 A-LDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKENAPEGTFLL---TVNASDP 2034
Query: 818 DEGTNALFMYT----LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG-- 871
DEG N+ Y+ L G + F++D TG + + LD E+K +Y++ ++A D G
Sbjct: 2035 DEGMNSAIEYSLRSKLRGIHSDPFNLDSTTGKLT-VKAGLDYEEKQVYEIKVLAADKGSV 2093
Query: 872 GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
LS+ +++ + D NDN PE +S +
Sbjct: 2094 SLSTHCNVVVRVEDVNDNPPEIEITSLSSSI 2124
Score = 77.4 bits (182), Expect = 3e-12
Identities = 110/454 (24%), Positives = 188/454 (41%), Gaps = 30/454 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V +LD NDN P F Y + N+ +G+++ K+ A D D G N ++Y +
Sbjct: 1227 SIVVRVLDVNDNAPSF-DREKYVVDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYSLYT 1285
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVE--ASDQPANPSERRYSLAVVTIEVTR 561
+ F +NP G + V E E +E ASD+ N + L TI+VT
Sbjct: 1286 SERTQQVFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKL---TIQVT- 1341
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
N P+I ++ V N+ + T + + V+D + D LH + +PF
Sbjct: 1342 DMNDNHPEISI---KSFQSPVKENIDVETVIAVVSVSDK-DSGDNGVVDLH-IPDKMPFK 1396
Query: 622 VEERSG---VITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERGVLL 677
+ + S + V + L R P YD V + + LS T+ ++DVND +
Sbjct: 1397 LRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDN---VP 1453
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI----A 733
+ S V EN+A A+ ++ N V F++ + T +
Sbjct: 1454 RFPQSFYTIRVTENNAPGALLSSLTAFDPDLHEN-QYLVYFILEKEIANTSMSMLFSINP 1512
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA-TY 792
E+G ++ K D E + + A + G + V I I D+NDN PV
Sbjct: 1513 ENGNLYALKTFDYEIEKEFLFHIEAR-DSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRA 1571
Query: 793 EGFIMENSKIGTEIKMDNIIK--ATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFI 849
+G ++E + K + K A D D N+ Y L +F +D+ G ++ +
Sbjct: 1572 QGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRTM 1631
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
R+ + +L +VA+D G + A + I +
Sbjct: 1632 RMFSYRDPR-HQRLVVVAKDNGDPALSATVTIKL 1664
Score = 77.0 bits (181), Expect = 4e-12
Identities = 107/474 (22%), Positives = 194/474 (40%), Gaps = 34/474 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFV-----PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V + ++D NDN PV V ++ E + + G+++ KV A+D D N
Sbjct: 1545 LSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 1604
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ Y L + ++ T+ S + N T+ + + RH V + +P+ A
Sbjct: 1605 RITYQLLQVTDATLFSLDQYNGEIRTMRMFS--YRDPRHQRLVVVAKDNGDPA----LSA 1658
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
VTI+++ K D P E+ + S++ + +G V+ + ++
Sbjct: 1659 TVTIKLSTVETAVKA-YSDMTEVPLEYDIFSDLNLYLVIGLGSVSFLLLITILVTIVIKC 1717
Query: 614 YEEGVPFAVEE-RSGVI----TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV---- 664
+ A R+ VI + + D + + Y + ++ L E +V V
Sbjct: 1718 QKPKASKAAPACRNSVISERNSTIADSTLVSNDAY-WYSLFLAETRKGKLVVRQPVPKGS 1776
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+ + RG L ++E G+A+G I + N+R L +
Sbjct: 1777 RYIVSSIPRGTGLTDTSGSAPSTLQEELKVGSAVGNIAKDLGLDVGRLTDRNLRLLSGTK 1836
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
QD+ DG + ++ +DRE+ +A V + ++QV I I D NDN
Sbjct: 1837 QDLFK--VNPSDGVLSVKRRVDREELCAKMAPCVANLKAVVENPLEMHQVIIEILDVNDN 1894
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE-- 841
P F Y ++E++ +G+ +++ A D + G N+L Y + + +E
Sbjct: 1895 APKFPEENYTLEVLESAMVGSRFQIEG---AHDLEVGINSLQTYKINNNQYFRVETEEFG 1951
Query: 842 NTGVVKF--IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
G V F + LDRE+ + L + A D G S + +++ D NDN P
Sbjct: 1952 EDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPP 2005
Score = 72.1 bits (169), Expect = 1e-10
Identities = 85/350 (24%), Positives = 158/350 (45%), Gaps = 33/350 (9%)
Query: 1001 VIVARSLPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+I+ ++L E + L ++A+DGG S+ V V DVND+ P F + Y +V E
Sbjct: 1194 LILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYVVDVME 1253
Query: 1057 AQYTRRVLGKVDATDADFGQNANL--TYFIQPSD-TDLPFEISPLTGVLSVNGELDRETE 1113
++ K++ATD D G N+++ +Y + S+ T F ++P G + V ++ E
Sbjct: 1254 NSPIGSLVLKLNATDLDEGSNSDIVYSYSLYTSERTQQVFHLNPENGEIRVREMINYEDL 1313
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
+ + V+A D G D+NDN P+ + ++ P + +
Sbjct: 1314 KLFEMEVIASDKGPNLLSGQCKLTIQVT-DMNDNHPEI----SIKSFQSPVKENIDVETV 1368
Query: 1174 ESVMMIPVYKA----TIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRK---NQQ 1225
+V+ + + ++ + P ++D + + L +P+
Sbjct: 1369 IAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVT 1428
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--- 1282
+ G P LS + + + DV D V P F +Y + + EN NAP L+S +LT
Sbjct: 1429 DRGSPPLSDNETMTLELLDVNDNV-----PRFPQSFYTIRVTEN-NAPGALLS-SLTAFD 1481
Query: 1283 -EHYENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
+ +EN + Y+IL + +T + F I+P NG LY +++ D E++ +
Sbjct: 1482 PDLHENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEKEF 1531
Score = 71.3 bits (167), Expect = 2e-10
Identities = 47/178 (26%), Positives = 86/178 (48%), Gaps = 8/178 (4%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
+A D D+G + Y L + + +G+ F + L + +QA L + A
Sbjct: 1156 NAADPDVGSNSVKDYHLSASEHFSINIQTGRDGTKFADLILTKALDREMQA-VHNLILTA 1214
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P +T A + + +LD+NDN P F+ + Y + ++EN P G VL++ ATD D+G N
Sbjct: 1215 VDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYVVDVMENSPIGSLVLKLNATDLDEGSN 1274
Query: 339 GEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+ Y + + F ++P +G + VR +++ E M+V A + P+++
Sbjct: 1275 SDIVYSYSLYTSERTQQVFHLNPENGEIRVRE--MINYEDLKLFEMEVIASDKGPNLL 1330
Score = 70.1 bits (164), Expect = 4e-10
Identities = 67/247 (27%), Positives = 105/247 (42%), Gaps = 22/247 (8%)
Query: 912 GTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
GTA ++ V N A D+ + + EN PIG+ ++KLNA DLD G N I Y ++
Sbjct: 1224 GTASI-VVRVLDVNDNAPSFDREKYVVDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYS 1282
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LND 1027
+Y + ++ F +N +G + V + E F + + A D G L+
Sbjct: 1283 --LY--------TSERTQQVFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSG 1332
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+ + V D+ND+ P + V+E V+ V +D D G N + I
Sbjct: 1333 QCKLTIQVTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDK 1392
Query: 1088 DTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+PF++ + L V+ LDRE +Y +T D G DV
Sbjct: 1393 ---MPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRG-SPPLSDNETMTLELLDV 1448
Query: 1145 NDNSPKF 1151
NDN P+F
Sbjct: 1449 NDNVPRF 1455
Score = 68.5 bits (160), Expect = 1e-09
Identities = 57/215 (26%), Positives = 96/215 (44%), Gaps = 15/215 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ ENI + T I ++ D DSG NG + ++ + S + E+ V++E
Sbjct: 442 VKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYEL----VVSEP-- 495
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ R PE + ++ L+DN ++ + + DVND+ P F +++Y V E
Sbjct: 496 ---LDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNA 552
Query: 1060 TRRVLGKVDATDADFGQNANLTYFI---QPSDTDLP--FEISPLTGVLSVNGELDRETED 1114
+L + A D D +N L YFI + ++T + F I+P G L D E E
Sbjct: 553 PGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEK 612
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+++ + ARD+G D NDN+P
Sbjct: 613 EFLFHIEARDSG-SPPLSSNVTVHIVIVDQNDNAP 646
Score = 68.5 bits (160), Expect = 1e-09
Identities = 57/215 (26%), Positives = 96/215 (44%), Gaps = 15/215 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ ENI + T I ++ D DSG NG + ++ + S + E+ V++E
Sbjct: 1359 VKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYEL----VVSEP-- 1412
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+ R PE + ++ L+DN ++ + + DVND+ P F +++Y V E
Sbjct: 1413 ---LDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNA 1469
Query: 1060 TRRVLGKVDATDADFGQNANLTYFI---QPSDTDLP--FEISPLTGVLSVNGELDRETED 1114
+L + A D D +N L YFI + ++T + F I+P G L D E E
Sbjct: 1470 PGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEK 1529
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+++ + ARD+G D NDN+P
Sbjct: 1530 EFLFHIEARDSG-SPPLSSNVTVHIVIVDQNDNAP 1563
Score = 68.1 bits (159), Expect = 2e-09
Identities = 155/678 (22%), Positives = 258/678 (38%), Gaps = 80/678 (11%)
Query: 47 DSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPY 102
DS + + G D++E ++ G +S + +V V +EDVNDN P T
Sbjct: 2061 DSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSL 2120
Query: 103 HVTVDELTPTGEKAFIFLIAPIGPSL------TIPLTVPRGLTIFKDIRAFDR-DKPNTP 155
++ E P G + + + ++P +P L D ++ K
Sbjct: 2121 SSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAHLPFDLKPSPDGHSYSLVTKDYLD 2180
Query: 156 NSDVH-YSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL 213
H Y I ++ D G AL S+ + + V D E +
Sbjct: 2181 KESTHMYDIQITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKAGSSV 2240
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFS---LDSVNGSLFLEKELDLDAEHNLQAN 270
F + A D D G A L Y LI D + S ++ NG++ K D +
Sbjct: 2241 FT--VSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISALKTFDFET-----LK 2293
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS----------IVENLP 320
TF QV AS +P ++ V++ +LD NDN P V Y +S I N+
Sbjct: 2294 TFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAP---VILYPVSSNGSAEGLEEIPRNVN 2350
Query: 321 NGFSVLQVMATDKDQGENGEFTYQLDD--PKGAFSIDPRSGWL-TVRNQTVLDREAHSSL 377
G V +V A D D G NG + L + F +D +G + T+R+ T D H
Sbjct: 2351 AGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEH--- 2407
Query: 378 RMKVYAKET-NPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKT--ENIEY 434
++ + K+ N S+ T ++ +P E A + + V D+ G T I
Sbjct: 2408 KLVILVKDNGNVSLSATATVLVKLV----EPKEAFAASDVQSSVRDDEGGHVTFYLMITL 2463
Query: 435 YDEQLMSFVNVEVTLL----DANDNNPVFVPSNLYEFSM------KSNAK-------VGT 477
++ +++ V + + D +VP Y+ ++ +S K GT
Sbjct: 2464 GSVSVLFIISIIVLIAMQCSKSPDYTSKYVPETNYDGTLCHSIQYRSGDKRYIEANQPGT 2523
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQR--TSNLTITSPFKINPNTGTVSVAESPILE--GRHA 533
+ VKA D D N V Y + R + +TS IN TG + +S E
Sbjct: 2524 SVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDFETLKTFQ 2583
Query: 534 LFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG 593
V ASD + ++ V ++ + A + NV G V
Sbjct: 2584 FQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVT 2643
Query: 594 QIRVNDAFEQNDVSYD--LLHGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEAV 648
++R DA D+ Y+ LL +E F ++ +G I + + + + +
Sbjct: 2644 KVRAYDA----DIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VI 2698
Query: 649 ALQENANLSIVTNATVHV 666
+++N N+S+ ATV V
Sbjct: 2699 LVKDNGNVSLSATATVLV 2716
Score = 67.3 bits (157), Expect = 3e-09
Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 21/200 (10%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F +PEN G+++ ++A D+DSG N + Y S + L + + INE
Sbjct: 2228 FYVPENNKAGSSVFTVSASDVDSGQNAALSY----------SLIRNQDLTITSFLNINEA 2277
Query: 998 HGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPV-FKKTWYNF 1052
+G + ++ E+ F+ + A D G +L+ N++V+VF+ D ND+ PV N
Sbjct: 2278 NGTISALKTFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNG 2337
Query: 1053 NVEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
+ E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 2338 SAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLR 2397
Query: 1107 ELDRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 2398 SFTETDEAEHKLVILVKDNG 2417
Score = 63.3 bits (147), Expect = 5e-08
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 35/288 (12%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S L++TV + D+NDN P+ Y VTV E P G F+ + P + +
Sbjct: 1988 SGNLNITVIVSDINDNPPVCDKQKYVVTVKENAPEG--TFLLTVNASDPDEGMNSAIEYS 2045
Query: 138 LTIFKDIRAFDRDKPNTPNSDVHYSIVSG---------------NDDGHFALESSHKPVL 182
L +R D N ++ ++ +G D G +L S+H V+
Sbjct: 2046 LR--SKLRGIHSDPFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSL-STHCNVV 2102
Query: 183 LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISG 238
+ +V D + E ++ ++S E P + A+ D+D GV + + +
Sbjct: 2103 V--RVEDVNDNPPEIEITSLSSSI---PEDAPPGTVVALMGVTDRDSGVNGQVICSVPAH 2157
Query: 239 NDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELL 297
L S D + SL + LD ++ H + +Q+ A L +P ++ + +++L
Sbjct: 2158 LPFDLKPSPDGHSYSLVTKDYLDKESTH-----MYDIQITAKDLGSPALSSTKVIHVDVL 2212
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
D+NDN P F Y + EN G SV V A+D D G+N +Y L
Sbjct: 2213 DVNDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVDSGQNAALSYSL 2260
Score = 61.3 bits (142), Expect = 2e-07
Identities = 70/300 (23%), Positives = 126/300 (42%), Gaps = 34/300 (11%)
Query: 69 RIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGP 126
R+ A + ++ V I D+NDN P F H+ + E + GE+ + A +G
Sbjct: 1105 RLDATIENPVRMFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGS 1164
Query: 127 S------------LTIPLTVPRGLTIFKDI---RAFDRDKPNTPNSDVHYSIVSGNDDGH 171
+ +I + R T F D+ +A DR+ VH I++ D G
Sbjct: 1165 NSVKDYHLSASEHFSINIQTGRDGTKFADLILTKALDREM-----QAVHNLILTAVDGGV 1219
Query: 172 FALESSHKPVLLLRKVLDYDAG-DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGAT 230
+ V+ + V D D+E +V + I +L ++A D D G +
Sbjct: 1220 PTRTGTASIVVRVLDVNDNAPSFDREKYVVDVMENSPIGSLVL---KLNATDLDEGSNSD 1276
Query: 231 LRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
+ Y S +++F L+ NG + + + ++ + F ++V AS L +
Sbjct: 1277 IVYSYSLYTSERTQQVFHLNPENGEIRVREMINYE-----DLKLFEMEVIASDKGPNLLS 1331
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
Q ++ I++ D+NDN PE + + + EN+ + V +DKD G+NG + D
Sbjct: 1332 GQCKLTIQVTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPD 1391
Score = 59.3 bits (137), Expect = 8e-07
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 13/134 (9%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
++ + + I D NDN P F T I E+S +G ++N A D D G+N++ Y L
Sbjct: 1116 MFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNN---AADPDVGSNSVKDYHL 1172
Query: 830 FGEGKEMFDVDENTGV--VKF----IGDSLDREKKIMYKLSLVARDTG--GLSSEAELII 881
E F ++ TG KF + +LDRE + ++ L L A D G + A +++
Sbjct: 1173 --SASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVV 1230
Query: 882 MIGDENDNKPEFNQ 895
+ D NDN P F++
Sbjct: 1231 RVLDVNDNAPSFDR 1244
Score = 58.0 bits (134), Expect = 2e-06
Identities = 47/175 (26%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 220 AIDQDLGVGATLRYELISGN----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
A D ++G+ + Y++ + + + F D L L ++LD + Q L+
Sbjct: 1922 AHDLEVGINSLQTYKINNNQYFRVETEEFGEDGKVPFLILHRQLDRE-----QTAQHWLK 1976
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A P+K+ + + + D+NDN P + Y +++ EN P G +L V A+D D+
Sbjct: 1977 VTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDE 2036
Query: 336 GENGEFTYQLDDP-----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G N Y L F++D +G LTV+ LD E +KV A +
Sbjct: 2037 GMNSAIEYSLRSKLRGIHSDPFNLDSTTGKLTVK--AGLDYEEKQVYEIKVLAAD 2089
Score = 58.0 bits (134), Expect = 2e-06
Identities = 53/198 (26%), Positives = 89/198 (44%), Gaps = 20/198 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I N P GT++ + A D D N ++ Y + P +KL++ + IN G
Sbjct: 2516 IEANQP-GTSVFAVKAFDRDENDNARVSYHILRDGS-PENKLTS-------FLNINSETG 2566
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK-KTWYNFNV 1054
++ +S E+ F+ + A D G+ L+ N++V+VF+ D ND+ PV N +
Sbjct: 2567 DILALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSA 2626
Query: 1055 EEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
E + R ++ KV A DAD G N L + +Q F + TG +
Sbjct: 2627 EGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSF 2686
Query: 1109 DRETEDKYILTVVARDNG 1126
E ++ L ++ +DNG
Sbjct: 2687 TETDEAEHKLVILVKDNG 2704
Score = 57.6 bits (133), Expect = 2e-06
Identities = 43/164 (26%), Positives = 74/164 (45%), Gaps = 6/164 (3%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G I ++ ++ E ++ M VIA +KG +G ++TI + D NDN P +++
Sbjct: 1298 ENGEIRVREMINYEDLKLFEMEVIAS-DKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQ 1356
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
+ EN + T I ++ +D D G N + + + + + + L
Sbjct: 1357 SPVKENIDVETVIA---VVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELVVSEPL 1413
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
DREK Y ++ D G LS + + + D NDN P F Q
Sbjct: 1414 DREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQ 1457
Score = 55.6 bits (128), Expect = 1e-05
Identities = 102/457 (22%), Positives = 184/457 (40%), Gaps = 41/457 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + N+EV + D NDN P F ++ + ++ VG A DPD+G N +
Sbjct: 312 ENPVRMFNIEVEITDINDNAPHFRRGTMH-LDISESSSVGERFSLNNAADPDVGSNSVKD 370
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
Y L + + F IN TG + ++ +A D+ + ++L +
Sbjct: 371 YHLSASEH------FSINIQTGRDGTKFADLI------LTKALDREM---QAVHNLILTA 415
Query: 557 IEVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++ T+ + D P+ ++ V N+ + T + + V+D ++ DL H
Sbjct: 416 VDGGVPTRTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDL-H-IP 473
Query: 616 EGVPFAVEERSG---VITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVND 671
+ +PF + + S + V + L R P YD V + + LS T+ ++DVND
Sbjct: 474 DKMPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVND 533
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + S V EN+A A+ ++ N V F++ + T
Sbjct: 534 N---VPRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQY-LVYFILEKEIANTSMSM 589
Query: 732 I----AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ E+G ++ K D E + + A + G + V I I D+NDN PV
Sbjct: 590 LFSINPENGNLYALKTFDYEIEKEFLFHIEAR-DSGSPPLSSNVTVHIVIVDQNDNAPVI 648
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVV 846
+ + G E D + A D D N+ Y L +F +D+ G +
Sbjct: 649 ----VSPWRAQGLCGGGE---DPQVIALDVDSVHNSRITYKLLQVTDATLFSLDQYNGEI 701
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ + R+ + +L +VA+D G + A + I +
Sbjct: 702 RTMRMFSYRDPR-HQRLVVVAKDNGDPALSATVTIKL 737
Score = 54.8 bits (126), Expect = 2e-05
Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 27/242 (11%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FL 719
N V + D+ND +G H+ + S +++G+ F N ++ G+ +V+ +
Sbjct: 319 NIEVEITDINDNAPHFRRGT-----MHL-DISESSSVGERFSLNNAADPDVGSNSVKDYH 372
Query: 720 IANQQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
++ + + +I DGT F K LDRE + V+ + + A + G G+ T
Sbjct: 373 LSASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTA------VDG-GVPTRT- 424
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
D NDN P +++ + EN + T I ++ +D D G N + + +
Sbjct: 425 ---DMNDNHPEISIKSFQSPVKENIDVETVIA---VVSVSDKDSGDNGVVDLHIPDKMPF 478
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ + + LDREK Y ++ D G LS + + + D NDN P F
Sbjct: 479 KLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRF 538
Query: 894 NQ 895
Q
Sbjct: 539 PQ 540
Score = 54.0 bits (124), Expect = 3e-05
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 20/198 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G + L A D D N + Y F E I + +S F IN +G
Sbjct: 1464 VTENNAPGALLSSLTAFDPDLHENQYLVY-FILEKEIANTSMSM-------LFSINPENG 1515
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTW-YNFNV 1054
++ ++ E EF +I A D G+ L+ N++V + + D ND+ PV W +V
Sbjct: 1516 NLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGSV 1575
Query: 1055 EEAQYTR-----RVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGEL 1108
E + R ++ KV A D D N+ +TY +Q +D L F + G +
Sbjct: 1576 VEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATL-FSLDQYNGEIRTMRMF 1634
Query: 1109 DRETEDKYILTVVARDNG 1126
L VVA+DNG
Sbjct: 1635 SYRDPRHQRLVVVAKDNG 1652
Score = 52.4 bits (120), Expect = 9e-05
Identities = 93/429 (21%), Positives = 166/429 (38%), Gaps = 37/429 (8%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA-TY 792
E+G ++ K D E + + A + G + V I I D+NDN PV
Sbjct: 840 ENGNLYALKTFDYEIEKEFLFHIEAR-DSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRA 898
Query: 793 EGFIMENSKIGTEIKMDNIIK--ATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFI 849
+G ++E + K + K A D D N+ Y L +F +D+ G ++ +
Sbjct: 899 QGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRTM 958
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
R+ + +L +VA+D G + A + I + ++ + E + E
Sbjct: 959 RMFSYRDPRHQ-RLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTE-----VPLEYD 1012
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
+ ++ + + + L LI + I K A + E
Sbjct: 1013 IFSDLNLYLV---------IGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVISE 1063
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI 1029
NS + + +S DA F+ R G ++V + +P S RL+ + + +
Sbjct: 1064 RNSTI-ADSTLVSNDAYWYS-LFLAETRKGKLVVRQPVPKGSP-RLDATIENPVRM---F 1117
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
++ V + D+ND+ P F++ + ++ E+ +A D D G N+ Y + S+
Sbjct: 1118 NIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASE- 1176
Query: 1090 DLPFEISPLTG-------VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
F I+ TG L + LDRE + + L + A D G
Sbjct: 1177 --HFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGG-VPTRTGTASIVVRVL 1233
Query: 1143 DVNDNSPKF 1151
DVNDN+P F
Sbjct: 1234 DVNDNAPSF 1242
Score = 51.6 bits (118), Expect = 2e-04
Identities = 80/354 (22%), Positives = 138/354 (38%), Gaps = 39/354 (11%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-- 123
+++ G N +S +T+ + D+NDN P + V E + ++
Sbjct: 1319 EVIASDKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKD 1378
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAFDR----------DKPNTPNSDVHYSIVSGNDDGHFA 173
G + + L +P + FK ++ D D+ P D+ +++ D G
Sbjct: 1379 SGDNGVVDLHIPDKMP-FKLRQSSDNYYELVVSEPLDREKVPEYDITFTVT---DRGSPP 1434
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRY 233
L + L L V D + I + +L + A D DL L Y
Sbjct: 1435 LSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALL--SSLTAFDPDLHENQYLVY 1492
Query: 234 -----ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
E+ + + LFS++ NG+L+ K D + E F+ ++A +P ++
Sbjct: 1493 FILEKEIANTSMSMLFSINPENGNLYALKTFDYEIE-----KEFLFHIEARDSGSPPLSS 1547
Query: 289 QARVEIELLDLNDNLPEFEVDF--YNISIVENLP----NGFSVLQVMATDKDQGENGEFT 342
V I ++D NDN P + + E +P G V +V+A D D N T
Sbjct: 1548 NVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRIT 1607
Query: 343 YQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
YQL A FS+D +G +R + R+ V AK+ +P++ T
Sbjct: 1608 YQLLQVTDATLFSLDQYNG--EIRTMRMFSYRDPRHQRLVVVAKDNGDPALSAT 1659
Score = 50.0 bits (114), Expect = 5e-04
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTW-YNFNVEEAQYTR----- 1061
E EF +I A D G+ L+ N++V + + D ND+ PV W +V E + R
Sbjct: 57 EKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKG 116
Query: 1062 RVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
++ KV A D D N+ +TY +Q +D L F + G + L V
Sbjct: 117 SLVAKVIALDVDSVHNSRITYQLLQVTDATL-FSLDQYNGEIRTMRMFSYRDPRHQRLVV 175
Query: 1121 VARDNG 1126
VA+DNG
Sbjct: 176 VAKDNG 181
Score = 49.6 bits (113), Expect = 6e-04
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 12/166 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+G L+SG + LF ++ +G L +++ +D + E + V ++A + N
Sbjct: 1820 DVGRLTDRNLRLLSGTKQDLFKVNPSDGVLSVKRRVDRE-ELCAKMAPCVANLKAV-VEN 1877
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
PL+ Q V IE+LD+NDN P+F + Y + ++E+ G A D + G N TY
Sbjct: 1878 PLEMHQ--VIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTY 1935
Query: 344 QLDDPK------GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
++++ + F D + +L + Q LDRE + +KV A
Sbjct: 1936 KINNNQYFRVETEEFGEDGKVPFLILHRQ--LDREQTAQHWLKVTA 1979
Score = 49.2 bits (112), Expect = 9e-04
Identities = 52/192 (27%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G + L A D D N + Y F E I + +S F IN +G
Sbjct: 547 VTENNAPGALLSSLTAFDPDLHENQYLVY-FILEKEIANTSMSM-------LFSINPENG 598
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ ++ E EF +I A D G+ L+ N++V + + D ND+ PV W +
Sbjct: 599 NLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGLC 658
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+V+ A D D N+ +TY +Q +D L F + G +
Sbjct: 659 GGGEDPQVI----ALDVDSVHNSRITYKLLQVTDATL-FSLDQYNGEIRTMRMFSYRDPR 713
Query: 1115 KYILTVVARDNG 1126
L VVA+DNG
Sbjct: 714 HQRLVVVAKDNG 725
Score = 48.8 bits (111), Expect = 0.001
Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 7/156 (4%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+E G I K D E ++ V+A + G S + V ++I D+NDN PV +
Sbjct: 2563 SETGDILALKSFDFETLKTFQFQVVAS-DSGSPSLSSNVTVKVFILDQNDNAPVILYPVS 2621
Query: 793 EGFIMEN-SKIGTEIKMDNI---IKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVK 847
E +I + ++ ++A DAD G N ++ L +F +D TG ++
Sbjct: 2622 SNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIR 2681
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ S + +KL ++ +D G +S A +++
Sbjct: 2682 TL-RSFTETDEAEHKLVILVKDNGNVSLSATATVLV 2716
Score = 48.4 bits (110), Expect = 0.002
Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 14/166 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L E+ + + LFS++ NG+L+ K D + E F+ ++A +P ++
Sbjct: 578 LEKEIANTSMSMLFSINPENGNLYALKTFDYEIE-----KEFLFHIEARDSGSPPLSSNV 632
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
V I ++D NDN P + + L G QV+A D D N TY+L
Sbjct: 633 TVHIVIVDQNDNAPVIVSPWR----AQGLCGGGEDPQVIALDVDSVHNSRITYKLLQVTD 688
Query: 351 A--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
A FS+D +G +R + R+ V AK+ +P++ T
Sbjct: 689 ATLFSLDQYNG--EIRTMRMFSYRDPRHQRLVVVAKDNGDPALSAT 732
Score = 47.2 bits (107), Expect = 0.003
Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 13/108 (12%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT----E 1283
G P LS + + + DV D V P F +Y + + EN NAP L+S +LT +
Sbjct: 514 GSPPLSDNETMTLELLDVNDNV-----PRFPQSFYTIRVTEN-NAPGALLS-SLTAFDPD 566
Query: 1284 HYENFKMRYYILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
+EN + Y+IL + +T + F I+P NG LY +++ D E++ +
Sbjct: 567 LHENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEKEF 614
Score = 46.4 bits (105), Expect = 0.006
Identities = 87/405 (21%), Positives = 155/405 (38%), Gaps = 37/405 (9%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA-T 791
AE+G ++ K D E + + A + G + V I I D+NDN PV
Sbjct: 41 AENGNLYALKTFDYEIEKEFLFHIEAR-DSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWR 99
Query: 792 YEGFIMENSKIGTEIKMDNIIK--ATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKF 848
+G ++E + K + K A D D N+ Y L +F +D+ G ++
Sbjct: 100 AQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRT 159
Query: 849 IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
+ R+ + +L +VA+D G + A + I + ++ + E + E
Sbjct: 160 MRMFSYRDPRHQ-RLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTE-----VPLEY 213
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRY 968
+ ++ + + + L LI + I K A +
Sbjct: 214 DIFSDLNLYLV---------IGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVIS 264
Query: 969 EFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDN 1028
E NS + + +S DA F+ R G ++V + +P S I N
Sbjct: 265 ERNSTI-ADSTLVSNDAYWYS-LFLAETRKGKLVVRQPVPKGSRLDATIE-----NPVRM 317
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
++ V + D+ND+ P F++ + ++ E+ +A D D G N+ Y + S+
Sbjct: 318 FNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASE 377
Query: 1089 TDLPFEISPLTG-------VLSVNGELDRETEDKYILTVVARDNG 1126
F I+ TG L + LDRE + + L + A D G
Sbjct: 378 ---HFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGG 419
Score = 45.6 bits (103), Expect = 0.011
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 13/162 (8%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ +PLDREK Y +T ++G + +T+ + D NDN P F + Y +
Sbjct: 490 LVVSEPLDREKVPEYDITFTVT-DRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVT 548
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENTGVVKFIGD 851
EN+ G + + A D D N +Y + + +F ++ G + +
Sbjct: 549 ENNAPGALLSS---LTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINPENGNLYAL-K 604
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
+ D E + + + ARD+G LSS + I+I D+NDN P
Sbjct: 605 TFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAP 646
Score = 45.2 bits (102), Expect = 0.014
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-- 351
+ELLD+NDN+P F FY I + EN G + + A D D EN Y + + + A
Sbjct: 526 LELLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANT 585
Query: 352 -----FSIDPRSG 359
FSI+P +G
Sbjct: 586 SMSMLFSINPENG 598
Score = 42.3 bits (95), Expect = 0.099
Identities = 39/160 (24%), Positives = 71/160 (44%), Gaps = 12/160 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVP-----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V + ++D NDN PV V ++ E + + G+++ KV A+D D N
Sbjct: 74 LSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 133
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ Y L + ++ T+ S + N T+ + + RH V + +P+ A
Sbjct: 134 RITYQLLQVTDATLFSLDQYNGEIRTMRMFS--YRDPRHQRLVVVAKDNGDPA----LSA 187
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG 593
VTI+++ K D P E+ + S++ + +G
Sbjct: 188 TVTIKLSTVETAVKA-YSDMTEVPLEYDIFSDLNLYLVIG 226
Score = 42.3 bits (95), Expect = 0.099
Identities = 39/160 (24%), Positives = 71/160 (44%), Gaps = 12/160 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVP-----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V + ++D NDN PV V ++ E + + G+++ KV A+D D N
Sbjct: 872 LSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 931
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ Y L + ++ T+ S + N T+ + + RH V + +P+ A
Sbjct: 932 RITYQLLQVTDATLFSLDQYNGEIRTMRMFS--YRDPRHQRLVVVAKDNGDPA----LSA 985
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG 593
VTI+++ K D P E+ + S++ + +G
Sbjct: 986 TVTIKLSTVETAVKA-YSDMTEVPLEYDIFSDLNLYLVIG 1024
Score = 41.5 bits (93), Expect = 0.17
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 10/120 (8%)
Query: 812 IKATDADEGTNALFMYTLFGEGK------EMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+KA D DE NA Y + +G +++ TG + + S D E ++ +
Sbjct: 2528 VKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILAL-KSFDFETLKTFQFQV 2586
Query: 866 VARDTG--GLSSEAELIIMIGDENDNKPE-FNQIEENSKVRIHRETKLNGTAGFTIIEVK 922
VA D+G LSS + + I D+NDN P + N E N AG + +V+
Sbjct: 2587 VASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVR 2646
Score = 39.9 bits (89), Expect = 0.53
Identities = 77/336 (22%), Positives = 136/336 (40%), Gaps = 42/336 (12%)
Query: 1001 VIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
+I+ ++L E + L ++A+DGG + R D+ND+ P + V+E
Sbjct: 395 LILTKALDREMQAVHNLILTAVDGG-----VPTRT---DMNDNHPEISIKSFQSPVKENI 446
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDK 1115
V+ V +D D G N + I +PF++ + L V+ LDRE +
Sbjct: 447 DVETVIAVVSVSDKDSGDNGVVDLHIPDK---MPFKLRQSSDNYYELVVSEPLDREKVPE 503
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKHPEADELSNHN 1172
Y +T D G DVNDN P+F + + E P A S
Sbjct: 504 YDITFTVTDRG-SPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTA 562
Query: 1173 FESVMMIPVYKA-TIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL---- 1227
F+ + Y I E T+++ +F+ + + NGN L + ++ L
Sbjct: 563 FDPDLHENQYLVYFILEKEIANTSMSMLFSINPE---NGNLYALKTFDYEIEKEFLFHIE 619
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE 1283
G P LSS + + + D D + PV +S + + P ++++L++ +
Sbjct: 620 ARDSGSPPLSSNVTVHIVIVDQND-----NAPVIVSPWRAQGLCGGGEDP-QVIALDV-D 672
Query: 1284 HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR 1319
N ++ Y +L D + F +D NG + +R
Sbjct: 673 SVHNSRITYKLLQVTDATL---FSLDQYNGEIRTMR 705
Score = 37.5 bits (83), Expect = 2.8
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ NP++ +E+E+ D+NDN P F ++ I E+ G A D D G N
Sbjct: 311 IENPVR--MFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSV 368
Query: 341 FTYQLDDPKGAFSIDPRSG 359
Y L + FSI+ ++G
Sbjct: 369 KDYHLSASE-HFSINIQTG 386
Score = 37.5 bits (83), Expect = 2.8
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
+ NP++ +E+E+ D+NDN P F ++ I E+ G A D D G N
Sbjct: 1110 IENPVR--MFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSV 1167
Query: 341 FTYQLDDPKGAFSIDPRSG 359
Y L + FSI+ ++G
Sbjct: 1168 KDYHLSASE-HFSINIQTG 1185
Score = 37.1 bits (82), Expect = 3.7
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
D+NDN PE + + + EN+ + V +DKD G+NG + D
Sbjct: 425 DMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPD 474
>UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Rep:
Protocadherin-21 - Homo sapiens (Human)
Length = 858
Score = 106 bits (255), Expect = 4e-21
Identities = 117/469 (24%), Positives = 194/469 (41%), Gaps = 29/469 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + + DAND P F+ Y + + G++I KV AVD D G G V Y LQ
Sbjct: 120 VVILVTDANDEAPRFIQEP-YVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQ---- 174
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV---TIEVTR 561
+ SPF ++ ++G + + L+ + + + R + VV T VT
Sbjct: 175 -NLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTV 233
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP 619
+ + P F+G PY +V + G+ V ++ D + N + Y L++G +G
Sbjct: 234 NVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSLVNG-NDGA- 291
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV----HVVDVNDERGV 675
F + E SG I++ ++ R +Y+ + + S ATV +VD+N+
Sbjct: 292 FEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVTIRIVDLNNHPPT 351
Query: 676 LL--KGAHSPIIFHVKENSAGAAI--GQIFHTNMSSIYGNGTGNVRFLIANQ--QDVTDD 729
G + + E+ I G N S N N++ + + V
Sbjct: 352 FYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLVGPRGIFRVVPQT 411
Query: 730 IAIAEDGTIFTQK--PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ TI + +D EK V ++A + V I + D NDN P F
Sbjct: 412 VLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKF 471
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV- 846
+ Y I EN+ G+ + + A D D G Y+ +G G ++F + +TG++
Sbjct: 472 DSLYYVARIPENAPGGSSVV---AVTAVDPDTGPWGEVKYSTYGTGADLFLIHPSTGLIY 528
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
SLD E Y + A D G S AE+ I + D ND+ P+F +
Sbjct: 529 TQPWASLDAEATARYNFYVKAEDMEGKYSVAEVFITLLDVNDHPPQFGK 577
Score = 85.8 bits (203), Expect = 8e-15
Identities = 139/596 (23%), Positives = 239/596 (40%), Gaps = 85/596 (14%)
Query: 580 FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN 639
F + + +G+ V + D E + +SY + F+V+ G IT+V++L R
Sbjct: 41 FSLPEDTPVGSHVYTLNGTDP-EGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDRER 99
Query: 640 RPMYDFEAV-ALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAI 697
+ EA+ ++ + NL + + V D NDE ++ P + V E+ AG+ I
Sbjct: 100 ED--EIEAIISISDGLNL-VAEKVVILVTDANDEAPRFIQ---EPYVALVPEDIPAGSII 153
Query: 698 GQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQK--PLDREKRDVYRM 754
++ + + G+G G+V + + Q++ A+ G + Q LD E+ + +
Sbjct: 154 FKVHAVDRDT--GSG-GSVTYFL---QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYI 207
Query: 755 TVIAEFNKGVISGAGIY-----QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
TV+A+ G + GA + VT+ +ED D PVF Y G++ E++ G+E+
Sbjct: 208 TVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLK- 266
Query: 810 NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
+ A D D G +Y+L F+++E +G + ++++ Y+L + +
Sbjct: 267 --VVAMDGDRGKPNRILYSLVNGNDGAFEINETSGAISITQSPAQLQREV-YELHVQVTE 323
Query: 870 TGGLSSEA-----ELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK 924
S A + I I D N++ P F G +G P+
Sbjct: 324 MSPAGSPAAQATVPVTIRIVDLNNHPPTF-----------------YGESG-------PQ 359
Query: 925 NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
N+F L +++ P I +K+ D D G N +FN ++ P
Sbjct: 360 NRFELSMNEHPPQGEILRG-------LKITVNDSDQGANA----KFNLQLVGP-----RG 403
Query: 985 ALEVKRYFVINERHGHVIVARSLPPESE------FR-LNISALDGGNLNDNISVRVFVKD 1037
V V+NE +IV S + E F+ L + + V + + D
Sbjct: 404 IFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLD 463
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ P F +Y + E + V A D D G + Y + DL F I P
Sbjct: 464 TNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYSTYGTGADL-FLIHP 522
Query: 1098 LTGVLSVN--GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TG++ LD E +Y V A D DVND+ P+F
Sbjct: 523 STGLIYTQPWASLDAEATARYNFYVKAED---MEGKYSVAEVFITLLDVNDHPPQF 575
Score = 68.5 bits (160), Expect = 1e-09
Identities = 76/274 (27%), Positives = 118/274 (43%), Gaps = 22/274 (8%)
Query: 211 EILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS------LDSVNGSLFLEKELDLDAE 264
EIL I D D G A +L+ R +F L+ ++ +E +D E
Sbjct: 374 EILRGLKITVNDSDQGANAKFNLQLVG--PRGIFRVVPQTVLNEAQVTIIVENSAAIDFE 431
Query: 265 HNLQANTFVLQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
++ ++ A ++N P K ++ A V I+LLD NDN+P+F+ +Y I EN P G
Sbjct: 432 ---KSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGS 488
Query: 324 SVLQVMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
SV+ V A D D G GE Y F I P +G + + LD EA + V
Sbjct: 489 SVVAVTAVDPDTGPWGEVKYSTYGTGADLFLIHPSTGLIYTQPWASLDAEATARYNFYVK 548
Query: 383 AK--ETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLM 440
A+ E SV F + P + ++K T V V K E I+ E+
Sbjct: 549 AEDMEGKYSVAEVFI---TLLDVNDHPPQFGKSVQKKTMVLGTPV--KIEAIDEDAEEPN 603
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAK 474
+ V+ +T A N + S+ E +K++ +
Sbjct: 604 NLVDYSIT--HAEPANVFDINSHTGEIWLKNSIR 635
Score = 68.1 bits (159), Expect = 2e-09
Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 8/145 (5%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
R +FS+D G++ L +ELD + E ++A +++ L +V I + D N
Sbjct: 77 RSVFSVDPTFGNITLVEELDREREDEIEA--------IISISDGLNLVAEKVVILVTDAN 128
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
D P F + Y + E++P G + +V A D+D G G TY L + F++D SG
Sbjct: 129 DEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQNLHSPFAVDRHSGV 188
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKE 385
L ++ LD E + + V AK+
Sbjct: 189 LRLQAGATLDYERSRTHYITVVAKD 213
Score = 67.3 bits (157), Expect = 3e-09
Identities = 110/466 (23%), Positives = 195/466 (41%), Gaps = 50/466 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D D PVFV + Y + + G+ + KV A+D D G+ +LY L ++
Sbjct: 231 VTVNVEDVQDMAPVFVGTPYYGYVYEDTLP-GSEVLKVVAMDGDRGKPNRILYSLVNGND 289
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F+IN +G +S+ +SP R + +P+ + A V + +
Sbjct: 290 ----GAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVTIRIVDL 345
Query: 565 GNKPDIPDFMGAP-----YEFWVGSNVGIGTSVG--QIRVNDAFEQNDVSYDLL----HG 613
N P P F G +E + + G + +I VND+ + + ++L G
Sbjct: 346 NNHP--PTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLVGPRG 403
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYN---RPMYDFEAVALQENA--NLSIVTNATVHVVD 668
VP V + V +V++ + + + F+ +A++ N S + + ++D
Sbjct: 404 IFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLD 463
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
ND + K + + EN+ G + + T + G G V++ + D
Sbjct: 464 TNDN---VPKFDSLYYVARIPENAPGGS-SVVAVTAVDPDTGPW-GEVKY--STYGTGAD 516
Query: 729 DIAI-AEDGTIFTQK--PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
I G I+TQ LD E Y V AE +G S A ++ I + D ND+PP
Sbjct: 517 LFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDMEGKYSVAEVF---ITLLDVNDHPP 573
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
F + + ++ +GT +K++ I + DA+E N + E +FD++ +TG
Sbjct: 574 QFGKSVQKKTMV----LGTPVKIEAIDE--DAEEPNNLVDYSITHAEPANVFDINSHTGE 627
Query: 846 V--KFIGDSLDREKKI------MYKLSLVARDTGGLSSEAELIIMI 883
+ K SLD I ++ L + A+D G S ++ I
Sbjct: 628 IWLKNSIRSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKI 673
Score = 66.5 bits (155), Expect = 5e-09
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 23/194 (11%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G + Y L++GND F ++ +G++ + + + LQ + L VQ +
Sbjct: 269 AMDGDRGKPNRILYSLVNGNDGA-FEINETSGAISITQ-----SPAQLQREVYELHVQVT 322
Query: 280 QLN---NPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNG--FSVLQVM 329
+++ +P A V I ++DLN++ P F + + +S+ E+ P G L++
Sbjct: 323 EMSPAGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKIT 382
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRS------GWLTVRNQTVLDREAHSSLRMKVYA 383
D DQG N +F QL P+G F + P++ + V N +D E L K+ A
Sbjct: 383 VNDSDQGANAKFNLQLVGPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLA 442
Query: 384 KETN-PSVVGTFAD 396
E N P + AD
Sbjct: 443 VEVNTPEKFSSTAD 456
Score = 64.9 bits (151), Expect = 2e-08
Identities = 107/470 (22%), Positives = 192/470 (40%), Gaps = 50/470 (10%)
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKI 513
DN N+ FS+ + VG+ + + DP+ + Y + + + + S F +
Sbjct: 28 DNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPE---GDPISYHI--SFDPSTRSVFSV 82
Query: 514 NPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDF 573
+P G +++ E L+ +EA ++ L +V +V + P F
Sbjct: 83 DPTFGNITLVEE--LDREREDEIEAIISISD------GLNLVAEKVVILVTDANDEAPRF 134
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITV 631
+ PY V ++ G+ + ++ D V+Y L + + PFAV+ SGV+ +
Sbjct: 135 IQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQNLHS---PFAVDRHSGVLRL 191
Query: 632 VDDLSR-YNRPMYDFEAVALQENAN--------LSIVTNATVHVVDVNDERGVLLKGAHS 682
+ Y R + V ++ S T TV+V DV D V + +
Sbjct: 192 QAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYY 251
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
++ ++ G+ + ++ M G + + + N D +I TQ
Sbjct: 252 GYVY--EDTLPGSEVLKV--VAMDGDRGK-PNRILYSLVNGNDGAFEINETSGAISITQS 306
Query: 743 PLDREKRDVYRMTV-IAEFNK-GVISGAGIYQVTIYIEDENDNPPVFEHAT-----YEGF 795
P + R+VY + V + E + G + VTI I D N++PP F + +E
Sbjct: 307 PAQLQ-REVYELHVQVTEMSPAGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELS 365
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE---NTGVVKFIGDS 852
+ E+ G EI I D+D+G NA F L G V + N V I ++
Sbjct: 366 MNEHPPQG-EILRGLKITVNDSDQGANAKFNLQLVGPRGIFRVVPQTVLNEAQVTIIVEN 424
Query: 853 -----LDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEFNQI 896
++ K + +KL V +T SS A+++I + D NDN P+F+ +
Sbjct: 425 SAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKFDSL 474
Score = 64.5 bits (150), Expect = 2e-08
Identities = 59/194 (30%), Positives = 86/194 (44%), Gaps = 22/194 (11%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
LF +PE+ P+G+ + LN D + I Y + + PS S F ++
Sbjct: 40 LFSLPEDTPVGSHVYTLNGTDPEGD---PISYHISFD----PSTRSV--------FSVDP 84
Query: 997 RHGHVIVARSLPPESEFRLN--ISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G++ + L E E + IS DG NL V + V D ND P F + Y V
Sbjct: 85 TFGNITLVEELDREREDEIEAIISISDGLNLVAE-KVVILVTDANDEAPRFIQEPYVALV 143
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV--LSVNGELDRET 1112
E ++ KV A D D G ++TYF+Q + PF + +GV L LD E
Sbjct: 144 PEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQ--NLHSPFAVDRHSGVLRLQAGATLDYER 201
Query: 1113 EDKYILTVVARDNG 1126
+ +TVVA+D G
Sbjct: 202 SRTHYITVVAKDGG 215
Score = 58.4 bits (135), Expect = 1e-06
Identities = 63/248 (25%), Positives = 107/248 (43%), Gaps = 12/248 (4%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
LN A +I V N A Q + L+PE+IP G+ I K++A+D D+G G + Y
Sbjct: 113 LNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTY- 171
Query: 970 FNSEVYIPPS-KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDN 1028
F ++ P + + L ++ ++ + + RL+ + + +
Sbjct: 172 FLQNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVV---FSAT 228
Query: 1029 ISVRVFVKDVNDHFPVFKKT-WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+V V V+DV D PVF T +Y + E+ VL KV A D D G+ + Y + +
Sbjct: 229 TTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVL-KVVAMDGDRGKPNRILYSL-VN 286
Query: 1088 DTDLPFEISPLTGVLSVN---GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
D FEI+ +G +S+ +L RE + ++ V D+
Sbjct: 287 GNDGAFEINETSGAISITQSPAQLQREVYELHV-QVTEMSPAGSPAAQATVPVTIRIVDL 345
Query: 1145 NDNSPKFY 1152
N++ P FY
Sbjct: 346 NNHPPTFY 353
Score = 56.8 bits (131), Expect = 4e-06
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 10/197 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN-LQANTFVLQV 276
+HA+D+D G G ++ Y L N F++D +G L L+ LD E + T V +
Sbjct: 156 VHAVDRDTGSGGSVTYFL--QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKD 213
Query: 277 QASQLNNP--LKTAQARVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATDK 333
+L+ + +A V + + D+ D P F +Y + LP G VL+V+A D
Sbjct: 214 GGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLP-GSEVLKVVAMDG 272
Query: 334 DQGENGEFTYQL-DDPKGAFSIDPRSGWLTV-RNQTVLDREAHS-SLRMKVYAKETNPSV 390
D+G+ Y L + GAF I+ SG +++ ++ L RE + +++ + +P+
Sbjct: 273 DRGKPNRILYSLVNGNDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAA 332
Query: 391 VGTFADSQRIAKWRRQP 407
T + RI P
Sbjct: 333 QATVPVTIRIVDLNNHP 349
Score = 50.4 bits (115), Expect = 4e-04
Identities = 61/199 (30%), Positives = 86/199 (43%), Gaps = 25/199 (12%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E+ S +V + LLD NDN P F S Y + NA G+ + V AVDPD G G V
Sbjct: 449 EKFSSTADVVIQLLDTNDNVPKF-DSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVK 507
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSL 552
Y T F I+P+TG + L+ R+ +V+A D E +YS+
Sbjct: 508 YSTYGTG----ADLFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDM-----EGKYSV 558
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN-DAFEQND-VSYDL 610
A V I T + D P G + + +GT V ++ DA E N+ V Y +
Sbjct: 559 AEVFI-----TLLDVNDHPPQFGKSVQ---KKTMVLGTPVKIEAIDEDAEEPNNLVDYSI 610
Query: 611 LHGYEEGVPFAVEERSGVI 629
H V F + +G I
Sbjct: 611 THAEPANV-FDINSHTGEI 628
Score = 37.1 bits (82), Expect = 3.7
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAF 117
DE + ++ I GLN ++ V + + D ND P F+ PY V E P G F
Sbjct: 101 DEIEAIISISDGLNLVAE--KVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIF 154
Score = 36.7 bits (81), Expect = 4.9
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK 115
SA +VTV +EDV D P+F+ TPY+ V E T G +
Sbjct: 226 SATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSE 263
>UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor
(PC-LKC).; n=3; Xenopus tropicalis|Rep: Protocadherin
LKC precursor (PC-LKC). - Xenopus tropicalis
Length = 1312
Score = 106 bits (254), Expect = 5e-21
Identities = 179/726 (24%), Positives = 296/726 (40%), Gaps = 71/726 (9%)
Query: 212 ILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSV--NGSLFLEKELDLDAEHNLQA 269
I+F D D V T + I ND + +L + NGS+ L L+ + +
Sbjct: 144 IVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLNGSIILNDTLNYNEKSIFYQ 203
Query: 270 NTFVLQVQASQLNNPL--KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
T + +N ++ A V ++++DL D P+F Y++SI EN+ G ++ +
Sbjct: 204 MTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAPYSVSIEENIALGTTIFR 263
Query: 328 VMATDKDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
V A D D+G N E Y + D G F I+ +SG + V + +DREA ++
Sbjct: 264 VTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAK--IDREA--------LVQD 313
Query: 386 TNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNV 445
++ A + + N EK T T T + ++ +F N
Sbjct: 314 GEQVLLTVMAQEKNL----------NVNAEKAT-----STTTVTVRVLDINDNKPNFYNC 358
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG-MVLYDLQRTSN 504
E+ D D + S L E S+ +V K+ DPD +NG LY + +
Sbjct: 359 EI---DDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQD 415
Query: 505 LTITSPFKINPNTGTVS--VAESPILEGRHALFVEASDQPANPS--ERRYSLAVVTIEVT 560
SP ++ NTG + V +S ++ +E AN + + S A VTI++
Sbjct: 416 CFTVSPARVQ-NTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSYATVTIDII 474
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEGV 618
P+F Y V N GT +G I D+ E ++Y LL +
Sbjct: 475 ----DINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQI 530
Query: 619 PFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
F V+ SG IT V+ L R R +Y + + + N + + ++D NDE
Sbjct: 531 -FHVDSDSGEITAVNGNLLDRERRSLY-YATLQAADGLNATGTALLEITILDENDEIPTA 588
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ G+++ IF V EN+ I QI + N + + F + ++ G
Sbjct: 589 I-GSYN--IF-VNENTDDVRI-QIEAFDADEPNTNNS-RIEFELLPSVLSSNFSVNVTTG 642
Query: 737 TIFTQKPLDR----EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
I + PLDR EK + + + ++ GV S + VTI +ED NDN PVF Y
Sbjct: 643 LITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVEDLNDNVPVFSKTVY 702
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-----KEMFDVDENTGVVK 847
+ F+ E S I ++ + + + F + G G + + G++
Sbjct: 703 DFFVNE-STIAAQVGILLVSDQDQTELNNRVSFRISQGGSGNFIIRNQKVESGLYNGILS 761
Query: 848 FIGD-SLDREKKIMYKLSLVARDTG--GLS--SEAELIIMIGDENDNKPEFNQIEENSKV 902
D LD E + Y L + A+D G G+S + A + + D ND P + N+
Sbjct: 762 LDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATATASVQVLDLNDEPPYVDPSSLNNLF 821
Query: 903 RIHRET 908
+ T
Sbjct: 822 LLENRT 827
Score = 104 bits (249), Expect = 2e-20
Identities = 132/488 (27%), Positives = 214/488 (43%), Gaps = 58/488 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR--TSN 504
V + D NDN+PVF+ YE S++ + +G+++ V AVD D V Y + ++
Sbjct: 114 VIVEDRNDNDPVFL-GIPYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPND 172
Query: 505 LTITSPFKINPN-----TGTVSVAESPILEGRHALFVEASDQPA---NPSERRYSLAVVT 556
L + F I N T++ E I + + + A+D+ N R +LA V+
Sbjct: 173 LQSNNLFYILLNGSIILNDTLNYNEKSIF---YQMTINATDKGGLFHNHFMYRSTLAYVS 229
Query: 557 IEVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHG 613
++V + PD+ P F+ APY + N+ +GT++ ++ D +++ Y +
Sbjct: 230 LKVI-----DLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDS 284
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-----QENANLSI-----VTNAT 663
G+ F + +SG I V + R + D E V L ++N N++ T T
Sbjct: 285 SRHGL-FDINSKSGEIFVTAKIDR-EALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVT 342
Query: 664 VHVVDVNDERGVLLK--------GAHSPIIF--HVKENSA-GAAIGQIFHTNMSSIYG-N 711
V V+D+ND + A + F ++E+S+ + ++ T N
Sbjct: 343 VRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKN 402
Query: 712 GTGNVRFLIANQQD--VTDDIAIAEDGTIFT----QKPLDREKRDVYRMTVIAEFNKGVI 765
G N+ +L QD + G I +D EK + I + G+
Sbjct: 403 GNFNL-YLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQ 461
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
VTI I D ND+ P F TY +MEN GT+I I ATD D G
Sbjct: 462 DCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQI---GTITATDLDSGELGKI 518
Query: 826 MYTLFGEG-KEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
Y L E +++F VD ++G + + G+ LDRE++ +Y +L A D + A L I I
Sbjct: 519 TYQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGLNATGTALLEITI 578
Query: 884 GDENDNKP 891
DEND P
Sbjct: 579 LDENDEIP 586
Score = 67.3 bits (157), Expect = 3e-09
Identities = 81/345 (23%), Positives = 140/345 (40%), Gaps = 45/345 (13%)
Query: 53 VKFRLGCDFDEGDD-LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
V+ L D++ G LV++ + + V +ED NDN P+FL PY ++ E P
Sbjct: 81 VQLALPLDYEVGFQYLVQLLRNIPALQVIRQFPVIVEDRNDNDPVFLGIPYEASIREDQP 140
Query: 112 TGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFD------------RDKPNTPNSDV 159
G F +P+T I D+++ + D N +
Sbjct: 141 LGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLNGSIILNDTLNYNEKSI 200
Query: 160 HYSI-VSGNDDG-----HFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEIL 213
Y + ++ D G HF S+ V L KV+D D + Q + I + I
Sbjct: 201 FYQMTINATDKGGLFHNHFMYRSTLAYVSL--KVIDLP--DLDPQFINAPYSVSIEENIA 256
Query: 214 FPEPIH---AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDA---EHNL 267
I AID D G+ ++Y + + LF ++S +G +F+ ++D +A +
Sbjct: 257 LGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAKIDREALVQDGEQ 316
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF------EVDFY---NISIVEN 318
T + Q + +N T+ V + +LD+NDN P F + DF +S +
Sbjct: 317 VLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGE 376
Query: 319 LPNGFSV------LQVMATDKDQGENGEFT-YQLDDPKGAFSIDP 356
+ S+ L++ D D+ +NG F Y + F++ P
Sbjct: 377 IEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSP 421
Score = 66.9 bits (156), Expect = 4e-09
Identities = 80/325 (24%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ P+G+ + ++A+D D +G++ ++ + IP S + Y ++N G
Sbjct: 135 IREDQPLGSIVFSVSAVDFDD--DGRVPVTYSIDEIIPNDLQSNNLF----YILLN---G 185
Query: 1000 HVIVARSLPPESE---FRLNISALDGGNLNDN--------ISVRVFVKDVNDHFPVFKKT 1048
+I+ +L + +++ I+A D G L N V + V D+ D P F
Sbjct: 186 SIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINA 245
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
Y+ ++EE + +V A D D G N + Y IQ S F+I+ +G + V ++
Sbjct: 246 PYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAKI 305
Query: 1109 DRET----EDKYILTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
DRE ++ +LTV+A++ N D+NDN P FY
Sbjct: 306 DREALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNC------- 358
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA--KVFANDTDFIGNGNGLILYSLP 1219
E+ + +F + + + IEE++ I VA K+ +D D NGN LY
Sbjct: 359 -----EIDDCDFSAAPTLS-FLGEIEEHSSIRVPVAKLKITGHDPDKDKNGN-FNLYLRG 411
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVAD 1244
+ ++ + + +T ++ V V D
Sbjct: 412 KDQDCFTVSPARVQNTGLIQVLVKD 436
Score = 64.5 bits (150), Expect = 2e-08
Identities = 68/258 (26%), Positives = 106/258 (41%), Gaps = 28/258 (10%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V + + D+NDH P F + Y V E +G + ATD D G+ +TY + P
Sbjct: 468 TVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESI 527
Query: 1090 DLPFEISPLTG-VLSVNGE-LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
F + +G + +VNG LDRE Y T+ A D D ND
Sbjct: 528 RQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADG---LNATGTALLEITILDENDE 584
Query: 1148 SP----KFYAF------DELLEWKHPEADE--LSNHNFESVMMIPVYKATIEENAPIGTT 1195
P + F D ++ + +ADE +N E ++ V + N G
Sbjct: 585 IPTAIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTG-L 643
Query: 1196 VAKVFANDTDFIG-NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
+ + D + I NG I+ ++ +LG+PSLSS + + V D+ D V
Sbjct: 644 ITSIGPLDREAIDEKDNGCIVLTV----KLYDLGVPSLSSEVNVTINVEDLNDNV----- 694
Query: 1255 PVFISRYYELEIEENVNA 1272
PVF Y+ + E+ A
Sbjct: 695 PVFSKTVYDFFVNESTIA 712
Score = 60.1 bits (139), Expect = 5e-07
Identities = 61/219 (27%), Positives = 95/219 (43%), Gaps = 20/219 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT I + A DLDSG G+I Y+ E + +D+ E+ +N G
Sbjct: 492 VMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQIFHVDSDSGEIT---AVN---G 545
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
+++ S + + A DG N + + + D ND P + YN V E
Sbjct: 546 NLL---DRERRSLYYATLQAADGLNATGTALLEITILDENDEIPTAIGS-YNIFVNENTD 601
Query: 1060 TRRVLGKVDATDAD--FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK-- 1115
R+ +++A DAD N+ + + + PS F ++ TG+++ G LDRE D+
Sbjct: 602 DVRI--QIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTGLITSIGPLDREAIDEKD 659
Query: 1116 ---YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+LTV D G D+NDN P F
Sbjct: 660 NGCIVLTVKLYDLG-VPSLSSEVNVTINVEDLNDNVPVF 697
Score = 56.8 bits (131), Expect = 4e-06
Identities = 71/302 (23%), Positives = 124/302 (41%), Gaps = 31/302 (10%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT--I 130
G+ +S+ ++VT+ +ED+NDNVP+F T Y V+E T + + + L +
Sbjct: 673 GVPSLSSEVNVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQVGILLVSDQDQTELNNRV 732
Query: 131 PLTVPRGLT-------------IFKDIRAFDRDKPNTPNSDVHYS-IVSGNDDG-----H 171
+ +G + ++ I + D D + +Y+ I+ D+G H
Sbjct: 733 SFRISQGGSGNFIIRNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSH 792
Query: 172 FALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAID--QDLGVGA 229
A ++ VL L Y + + + + E+L H D +L A
Sbjct: 793 TATATASVQVLDLNDEPPY-VDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQA 851
Query: 230 TLRYELISGNDRKLFSLDSV----NGSLFLEKELDLDAEHNLQANTFVLQVQAS-QLNNP 284
+GND D + NG LF+ +D E +L+V+ L
Sbjct: 852 LSLQCFKNGNDIGNICYDWIWLAPNGELFVNDTEVVDYEL-CDVMVMMLRVEDKLTLIGD 910
Query: 285 LKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ + +++LD+NDN PEF +VD + + + P + V V ATDKD G N +
Sbjct: 911 RYSKNESLRVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKF 970
Query: 344 QL 345
+
Sbjct: 971 SI 972
Score = 54.8 bits (126), Expect = 2e-05
Identities = 112/501 (22%), Positives = 204/501 (40%), Gaps = 83/501 (16%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+D+ L P F+ I ENI +GTTI ++ A+D D G+N +I+Y +
Sbjct: 233 IDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDI 292
Query: 982 SADALEVKRYFVINE----RHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKD 1037
++ + E+ I+ + G ++ + E LN++A + ++VRV D
Sbjct: 293 NSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKN--LNVNA-EKATSTTTVTVRVL--D 347
Query: 1038 VNDHFPVFKKTWYNFNVEEAQY----TRRVLG---------------KVDATDADFGQNA 1078
+ND+ P F YN +++ + T LG K+ D D +N
Sbjct: 348 INDNKPNF----YNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNG 403
Query: 1079 NLTYFIQPSDTDLPFEISPL----TGVLSV----NGELDRE-TEDKYILTVVARDNGXXX 1129
N +++ D D F +SP TG++ V + +D E + +VA D G
Sbjct: 404 NFNLYLRGKDQDC-FTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQD 462
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH--PEADELSNHNFESVMMIPVYKATIE 1187
D+ND++P+F LE P+ ++ + + K T +
Sbjct: 463 CCSYATVTIDII-DINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQ 521
Query: 1188 ENAPIGTTVAKVFANDTDF--IGNGNGLIL----YSLPQRKNQQNLGLPSLSSTAILMVT 1241
+ ++ ++F D+D I NG +L SL Q GL + + TA+L +T
Sbjct: 522 L---LPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGL-NATGTALLEIT 577
Query: 1242 VADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE-HYENFKMRYYILNENDT 1300
+ D DE+ P I Y E + +++ + + E + N ++ + +L +
Sbjct: 578 ILDENDEI-----PTAIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELL---PS 629
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
+ F ++ G + + DRE D E+ L +Y + L
Sbjct: 630 VLSSNFSVNVTTGLITSIGPLDREAID--------EKDNGCIVLTVKLYDLGVPSLSS-- 679
Query: 1361 KYDVKVVVRIKDVNDNSPKFT 1381
+V V + ++D+NDN P F+
Sbjct: 680 --EVNVTINVEDLNDNVPVFS 698
Score = 52.0 bits (119), Expect = 1e-04
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ-NANLTY 1082
+L+ ++V + V+D+ND+ PVF KT Y+F V E+ +V G + +D D + N +++
Sbjct: 676 SLSSEVNVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQV-GILLVSDQDQTELNNRVSF 734
Query: 1083 FIQPSDT------DLPFEISPLTGVLSVNGE--LDRETEDKYILTVVARDNG-XXXXXXX 1133
I + + E G+LS++ + LD ET+ Y L + A+DNG
Sbjct: 735 RISQGGSGNFIIRNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTA 794
Query: 1134 XXXXXXXXXDVNDNSP 1149
D+ND P
Sbjct: 795 TATASVQVLDLNDEPP 810
Score = 51.2 bits (117), Expect = 2e-04
Identities = 63/294 (21%), Positives = 123/294 (41%), Gaps = 17/294 (5%)
Query: 63 EGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA 122
E + +V GL +Y +VT+ I D+ND+ P F Y++ V E P G +
Sbjct: 449 EVEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITAT 508
Query: 123 PIGPSLTIPLT---VPRGL-TIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHF 172
+ +T +P + IF +I A + + + ++Y+ + DG
Sbjct: 509 DLDSGELGKITYQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQA-ADGLN 567
Query: 173 ALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
A ++ + +L + + + + + + + +I E A D+ + +
Sbjct: 568 ATGTALLEITILDENDEIPTAIGSYNIFVNENTDDVRIQI---EAFDA-DEPNTNNSRIE 623
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+EL+ FS++ G + LD +A VL V+ L P +++ V
Sbjct: 624 FELLPSVLSSNFSVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNV 683
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE-NGEFTYQL 345
I + DLNDN+P F Y+ + E+ V ++ +D+DQ E N ++++
Sbjct: 684 TINVEDLNDNVPVFSKTVYDFFVNES-TIAAQVGILLVSDQDQTELNNRVSFRI 736
Score = 45.2 bits (102), Expect = 0.014
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 12/111 (10%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
I Q + +ED NDN PVF YE I E+ +G+ + + A D D+ Y++
Sbjct: 109 IRQFPVIVEDRNDNDPVFLGIPYEASIREDQPLGSIVFS---VSAVDFDDDGRVPVTYSI 165
Query: 830 FG------EGKEMFDVDENTGVVKFIGDSLD-REKKIMYKLSLVARDTGGL 873
+ +F + N ++ + D+L+ EK I Y++++ A D GGL
Sbjct: 166 DEIIPNDLQSNNLFYILLNGSII--LNDTLNYNEKSIFYQMTINATDKGGL 214
Score = 39.9 bits (89), Expect = 0.53
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 23/154 (14%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKM 1290
S+ A + + V D+PD P FI+ Y + IEEN+ + + + N ++
Sbjct: 223 STLAYVSLKVIDLPDL-----DPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEI 277
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE--VKDTYEVIVRAERQKYSRELPHMI 1348
+Y I D+ F I+ ++G +++ DRE V+D +V++ Q+ + +
Sbjct: 278 QYSI---QDSSRHGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNVN--- 331
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
AE T V VR+ D+NDN P F N
Sbjct: 332 ---AEKATSTTT-----VTVRVLDINDNKPNFYN 357
Score = 37.9 bits (84), Expect = 2.1
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I++V LDVD++ ++P+ PI + + A D DSGLN +++ S +I
Sbjct: 922 ILDVNDNAPEFLDVDEV--FVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVEFIS 979
Query: 978 PSKLSADALEVKRYFVINER---HGHVIVARSLPP--ESEFRLNISALDGGN 1024
+ L + +E+ G + VA SL + +R+ + A D GN
Sbjct: 980 GDS-TRPLLNIFTIVTTSEKEIYQGSIRVASSLDATLKGNYRVTVIAEDSGN 1030
Score = 36.7 bits (81), Expect = 4.9
Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 8/143 (5%)
Query: 991 YFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI-SVRVFVKDVNDHFPVFKKTW 1049
YF +N G V +A L E F+ + L I V V+D ND+ PVF
Sbjct: 71 YFNVNLMTGEVQLALPLDYEVGFQYLVQLLRNIPALQVIRQFPVIVEDRNDNDPVFLGIP 130
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSD--TDLPFEISPLTGVLSV 1104
Y ++ E Q ++ V A D D +TY I P+D ++ F I L G + +
Sbjct: 131 YEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYIL-LNGSIIL 189
Query: 1105 NGELD-RETEDKYILTVVARDNG 1126
N L+ E Y +T+ A D G
Sbjct: 190 NDTLNYNEKSIFYQMTINATDKG 212
>UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069E6F7 UniRef100 entry -
Xenopus tropicalis
Length = 602
Score = 106 bits (254), Expect = 5e-21
Identities = 145/506 (28%), Positives = 217/506 (42%), Gaps = 67/506 (13%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V++ + D ND++P F P + + + GT A DPD+G++G+ Y L R
Sbjct: 86 VQVDILVRDVNDHSPTF-PVHSLQLQVSELTPPGTSFRLPAAWDPDIGEHGLKGYALLRG 144
Query: 503 SNLTITSPFKINPNTG---------------TVSVAESPILE-------GRHALFVEASD 540
S +PF I G T+ + +++ + L VEA D
Sbjct: 145 SQ---EAPFIIRYGHGKTHNKRMVEGVGADSTLHPLDLVLIQWLDREELDNYQLEVEAFD 201
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
NP RR +V I V + P P F Y+ WV N IGTSV + D
Sbjct: 202 G-GNP--RRTGRLIVDIVVMDAN--DNP--PVFDQLDYKGWVWENAPIGTSVCTVHATDP 254
Query: 601 F--EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
+V Y L G EG F V+E SG I+V L R ++ V ++ +
Sbjct: 255 DLGSNGEVRYSLRFG--EGY-FTVDEESGEISVSRPLDREQISIHQL-VVQARDGGDQPE 310
Query: 659 VTNA--TVHVVDVNDERGVLLKGAHSPIIFHV--KENSAGAAIGQ----IFHTNMS---- 706
VT+ TV V+DVND G H +I E S GA G+ IF ++
Sbjct: 311 VTSILLTVKVLDVNDNS----PGIHITLITESGRPEVSEGARTGEYLARIFVSDPDLESE 366
Query: 707 -SIYGNGTGNVRFLI-ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
++ G R ++ + + A + + PLDRE +D+Y + ++A ++ G
Sbjct: 367 DEVWVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELKDMYELQILA-WDTGS 425
Query: 765 ISGAGIYQVTIYIEDENDNPPVF-EHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTN 822
+ + + D ND PP+F + Y+ I E + IGT + M +KA D DE G N
Sbjct: 426 PPLQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLM---LKAQDLDEDGPN 482
Query: 823 ALFMYTLF-GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAEL 879
+ Y+L + F ++ TGV+ I LD E + L VA D G LSS +
Sbjct: 483 SRVTYSLQESQNSSSFILEPGTGVLS-IAQLLDHESAPVLNLVAVATDHGSPPLSSSCTI 541
Query: 880 IIMIGDENDNKPEFNQIEENSKVRIH 905
I + D NDN P F Q N ++ H
Sbjct: 542 TITVEDTNDNDPIFLQQFYNVSLQEH 567
Score = 77.8 bits (183), Expect = 2e-12
Identities = 92/371 (24%), Positives = 153/371 (41%), Gaps = 24/371 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V++ ++DANDN PVF + Y+ + NA +GT + V A DPDLG NG V Y L+
Sbjct: 213 VDIVVMDANDNPPVFDQLD-YKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGEG 271
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F ++ +G +SV+ E H L V+A D P L V ++V
Sbjct: 272 Y-----FTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDN 326
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVG-----IGTSVGQIRVND-AFEQNDVSYDLLHGYEE 616
+ G + G P E G+ G I S + D + + D L+ E
Sbjct: 327 SPGIHITLITESGRP-EVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTERRLILEGGE 385
Query: 617 GVPFAVEERSG---VITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
G F+++ + V L R + MY+ + +A + L + V D+ND+
Sbjct: 386 G-SFSLQPAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQ 444
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ L+ + S G A+ + ++ N V + + Q+ + I
Sbjct: 445 PPMFLQPEGYQATIS-EATSIGTAVLMLKAQDLDEDGPNS--RVTYSLQESQNSSSFILE 501
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G + + LD E V + +A + G + +TI +ED NDN P+F Y
Sbjct: 502 PGTGVLSIAQLLDHESAPVLNLVAVAT-DHGSPPLSSSCTITITVEDTNDNDPIFLQQFY 560
Query: 793 EGFIMENSKIG 803
+ E++ +G
Sbjct: 561 NVSLQEHTVLG 571
Score = 77.4 bits (182), Expect = 3e-12
Identities = 137/567 (24%), Positives = 228/567 (40%), Gaps = 84/567 (14%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+E G + T + LDRE+R+ Y F + G + QV I + D ND+ P F +
Sbjct: 55 SETGIVSTLQVLDRERREHY------SFVAATLQGE-VVQVDILVRDVNDHSPTFPVHSL 107
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ + E + GT ++ A D D G + L Y L G + E ++++ G
Sbjct: 108 QLQVSELTPPGTSFRLP---AAWDPDIGEHGLKGYALL-RGSQ-----EAPFIIRY-GHG 157
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
K+++ V D+ + LI + E + + ++E R +L
Sbjct: 158 KTHNKRMVEG---VGADSTLHPLDLVLIQWLDREELDNYQL-EVEAFDGGNPRRTGRL-- 211
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
I V N DQL + EN PIGT++ ++A D D G NG++RY
Sbjct: 212 ---IVDIVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRF 268
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNIS 1030
+ YF ++E G + V+R L E S +L + A DGG+ + S
Sbjct: 269 G---------------EGYFTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPEVTS 313
Query: 1031 VRVFVK--DVNDHFPVFKKTWYNFN----VEEAQYTRRVLGKVDATDADFGQ-------- 1076
+ + VK DVND+ P T + V E T L ++ +D D
Sbjct: 314 ILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEG 373
Query: 1077 NANLTYFIQPSDTDLPFE-ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
+ ++ + + P L VN LDRE +D Y L ++A D G
Sbjct: 374 DTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELKDMYELQILAWDTG-SPPLQSHK 432
Query: 1136 XXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIG-- 1193
D+ND P F E + EA + +V+M+ ++E+ P
Sbjct: 433 TLLLSVTDLNDQPPMFLQ-PEGYQATISEATSIGT----AVLMLKA--QDLDEDGPNSRV 485
Query: 1194 TTVAKVFANDTDFI-GNGNGLI-LYSLPQRKNQQNLGL---------PSLSSTAILMVTV 1242
T + N + FI G G++ + L ++ L L P LSS+ + +TV
Sbjct: 486 TYSLQESQNSSSFILEPGTGVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITITV 545
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEEN 1269
D D + P+F+ ++Y + ++E+
Sbjct: 546 EDTND-----NDPIFLQQFYNVSLQEH 567
Score = 75.8 bits (178), Expect = 9e-12
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ + + L+V+A NP +T + V+I ++D NDN P F+ Y + EN P G SV
Sbjct: 189 ELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCT 248
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
V ATD D G NGE Y L +G F++D SG ++V LDRE S ++ V A++
Sbjct: 249 VHATDPDLGSNGEVRYSLRFGEGYFTVDEESGEISVSRP--LDREQISIHQLVVQARD 304
Score = 65.3 bits (152), Expect = 1e-08
Identities = 87/336 (25%), Positives = 138/336 (41%), Gaps = 36/336 (10%)
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
++L + A DGGN + V + V D ND+ PVF + Y V E + V AT
Sbjct: 193 YQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCTVHAT 252
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G N + Y ++ + F + +G +SV+ LDRE + L V ARD G
Sbjct: 253 DPDLGSNGEVRYSLRFGEGY--FTVDEESGEISVSRPLDREQISIHQLVVQARDGG-DQP 309
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
DVNDNSP + + E PE E E + I V +E
Sbjct: 310 EVTSILLTVKVLDVNDNSPGIH-ITLITESGRPEVSE-GARTGEYLARIFVSDPDLESED 367
Query: 1191 PI---GTTVAKVF--ANDTDFIGNGNGLILYSL----PQRKNQQNL----------GLPS 1231
+ G T ++ + F G LY L P + +++ G P
Sbjct: 368 EVWVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPP 427
Query: 1232 LSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVN---APVELVSLNLTEHYENF 1288
L S L+++V D+ D+ M +P Y+ I E + A + L + +L E N
Sbjct: 428 LQSHKTLLLSVTDLNDQPPMFLQP----EGYQATISEATSIGTAVLMLKAQDLDEDGPNS 483
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
++ Y + ++ +F+++P G L + + D E
Sbjct: 484 RVTYSLQESQNSS---SFILEPGTGVLSIAQLLDHE 516
Score = 55.6 bits (128), Expect = 1e-05
Identities = 79/328 (24%), Positives = 136/328 (41%), Gaps = 32/328 (9%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLIAP-IGPSLTIPLTVPRG- 137
L V + + D NDN P+F Y V E P G + P +G + + ++ G
Sbjct: 211 LIVDIVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGE 270
Query: 138 --LTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
T+ ++ +P + +H +V D G + +LL KVLD +
Sbjct: 271 GYFTVDEESGEISVSRPLDREQISIHQLVVQARDGGD---QPEVTSILLTVKVLDVNDNS 327
Query: 195 KEFQLVI--------MASGKRIHK---EILFPEP-IHAIDQDLGVGATLRYELISGNDRK 242
+ + ++ G R + I +P + + D+ G T R ++ G +
Sbjct: 328 PGIHITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTERRLILEGGEGS 387
Query: 243 LFSLDSVNGSL-FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
FSL L FL LD E + + LQ+ A +P + + + + DLND
Sbjct: 388 -FSLQPAGPQLYFLCVNAPLDRE---LKDMYELQILAWDTGSPPLQSHKTLLLSVTDLND 443
Query: 302 NLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQ-GENGEFTYQLDDPK--GAFSIDPR 357
P F + + Y +I E G +VL + A D D+ G N TY L + + +F ++P
Sbjct: 444 QPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTYSLQESQNSSSFILEPG 503
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G L++ +LD E+ L + A +
Sbjct: 504 TGVLSIAQ--LLDHESAPVLNLVAVATD 529
Score = 49.6 bits (113), Expect = 6e-04
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL-GQNGMVLY 497
L S + +++ D ND P+F+ Y+ ++ +GT + +KA D D G N V Y
Sbjct: 428 LQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTY 487
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAE 524
LQ + N +S F + P TG +S+A+
Sbjct: 488 SLQESQN---SSSFILEPGTGVLSIAQ 511
Score = 40.7 bits (91), Expect = 0.30
Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
Query: 220 AIDQDLGVGAT---LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
A+D+ L G +R L G+ + F L +G + ++ +D+E + + VL
Sbjct: 9 AVDEGLPPGTLVGDIRAGLPEGSPGEGFFLSEEDGESLVLRDFQVDSETGIVSTLQVLDR 68
Query: 277 QASQ----LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+ + + L+ +V+I + D+ND+ P F V + + E P G S A D
Sbjct: 69 ERREHYSFVAATLQGEVVQVDILVRDVNDHSPTFPVHSLQLQVSELTPPGTSFRLPAAWD 128
Query: 333 KDQGENGEFTYQL 345
D GE+G Y L
Sbjct: 129 PDIGEHGLKGYAL 141
Score = 39.5 bits (88), Expect = 0.69
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 221 IDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
+D+D G + + Y L + F L+ G L + + LD ++ A L A+
Sbjct: 476 LDED-GPNSRVTYSLQESQNSSSFILEPGTGVLSIAQLLDHES-----APVLNLVAVATD 529
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+P ++ + I + D NDN P F FYN+S+ E+ G LQ+
Sbjct: 530 HGSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSLQEHTVLGHCFLQL 577
Score = 37.9 bits (84), Expect = 2.1
Identities = 17/41 (41%), Positives = 26/41 (63%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G +S+ ++T+ +ED NDN PIFL Y+V++ E T G
Sbjct: 531 GSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSLQEHTVLG 571
>UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33;
Euteleostomi|Rep: Protocadherin-18 precursor - Homo
sapiens (Human)
Length = 1128
Score = 106 bits (254), Expect = 5e-21
Identities = 123/473 (26%), Positives = 189/473 (39%), Gaps = 32/473 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E L F ++EV +LD NDN+P F S L + +A VGT I A DPD+G+N +
Sbjct: 109 EHLQLF-HIEVEVLDINDNSPQFSRS-LIPIEISESAAVGTRIPLDSAFDPDVGENSLHT 166
Query: 497 YDLQRTS--NLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLA 553
Y L N+ + + + V E L+ + L + ASD +R +
Sbjct: 167 YSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGV---PQRSGSS 223
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
++ I ++ + P F Y + N +GT + + D E + Y
Sbjct: 224 ILKISISDSNDNS----PAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFS 279
Query: 612 HGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVD 668
+ F ++ G +T+ + Y+ + A N + + VVD
Sbjct: 280 SHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVD 339
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVT 727
VND + + SP + G I +G G + +
Sbjct: 340 VNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFK 399
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ I T LDREKR Y +TVIAE ++G S + + T+ I D NDNPP F
Sbjct: 400 LQKTYENNYLILTNATLDREKRSEYSLTVIAE-DRGTPSLSTVKHFTVQINDINDNPPHF 458
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEM---FDVDE 841
+ + YE I EN+ G I + ATD D G N YT+ F G + +D
Sbjct: 459 QRSRYEFVISENNSPGAYI---TTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDP 515
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDENDNKP 891
+ G + + D E+ + ARD G L S +++ I DENDN P
Sbjct: 516 SNGAIYALR-IFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVP 567
Score = 92.7 bits (220), Expect = 7e-17
Identities = 109/454 (24%), Positives = 192/454 (42%), Gaps = 30/454 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++++ D+NDN+P F + Y + N+ VGT++ + A DPD G NG ++Y +
Sbjct: 225 LKISISDSNDNSPAFEQQS-YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVS 283
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
I FKI+ G +++ + E + + V+A D N + + ++V
Sbjct: 284 PKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDV--- 340
Query: 563 TKGNKPDIPDFMGAPYE---FWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGV 618
NKP+I + +P + ++ I T V +RV D N LHG+
Sbjct: 341 -NDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFK 399
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
E + +I L R R Y +A +LS V + TV + D+ND
Sbjct: 400 LQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQ 459
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTDDIAI-AED 735
+ + +I + NS GA I + T+ G T + +T + I +
Sbjct: 460 RSRYEFVI--SENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSN 517
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY--IEDENDNPPV-----FE 788
G I+ + D E +V ++T + E G + T+ I DENDN PV
Sbjct: 518 GAIYALRIFDHE--EVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALR 575
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKEMFDVDENTGVVK 847
+ T E I + ++ G + I+A D D G NA L + G + +F +D + +
Sbjct: 576 NNTAEITIPKGAESGFHVTR---IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDI- 631
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
S+D ++LS++ +D G ++++
Sbjct: 632 HTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLL 665
Score = 80.2 bits (189), Expect = 4e-13
Identities = 54/168 (32%), Positives = 84/168 (50%), Gaps = 11/168 (6%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A+ + + LDRE + Y + + A + GV +G + I I D NDN P FE +Y
Sbjct: 186 AKYAELIVVRELDRELKSSYELQLTAS-DMGVPQRSGSSILKISISDSNDNSPAFEQQSY 244
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK----EMFDVDENTGVVKF 848
++ENS +GT + +D + ATD DEG N +Y+ E F +D G +
Sbjct: 245 IIQLLENSPVGT-LLLD--LNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTL 301
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
+D E Y++ + A+D G + + ++II + D NDNKPE N
Sbjct: 302 F-KQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEIN 348
Score = 77.8 bits (183), Expect = 2e-12
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 8/177 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + Y L + + + +G+ + E + + + L+++ + LQ+ AS
Sbjct: 154 AFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELKSS-YELQLTAS 212
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+ P ++ + ++I + D NDN P FE Y I ++EN P G +L + ATD D+G NG
Sbjct: 213 DMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANG 272
Query: 340 EFTYQLD---DPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
+ Y PK F ID G LT+ Q +D E S + V A++ P+ +
Sbjct: 273 KIVYSFSSHVSPKIMETFKIDSERGHLTLFKQ--VDYEITKSYEIDVQAQDLGPNSI 327
Score = 70.1 bits (164), Expect = 4e-10
Identities = 61/243 (25%), Positives = 99/243 (40%), Gaps = 21/243 (8%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I + N + +Q + + EN P+GT ++ LNA D D G NG+I Y F+S V
Sbjct: 227 ISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHV---- 282
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVF 1034
+ ++ F I+ GH+ + + + E + +++ A D G ++ + + +
Sbjct: 283 ------SPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIK 336
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQY------TRRVLGKVDATDADFGQNANLTYFIQPSD 1088
V DVND+ P + EE Y + V D D G N + +
Sbjct: 337 VVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHG 396
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
+ ++ N LDRE +Y LTV+A D G D+NDN
Sbjct: 397 HFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRG-TPSLSTVKHFTVQINDINDNP 455
Query: 1149 PKF 1151
P F
Sbjct: 456 PHF 458
Score = 68.9 bits (161), Expect = 1e-09
Identities = 109/442 (24%), Positives = 182/442 (41%), Gaps = 57/442 (12%)
Query: 929 LDVDQLGPLF---LIP----ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD++ P F LIP E+ +GT I +A D D G N Y ++ +
Sbjct: 121 LDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFN---- 176
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKD 1037
+EV R ++ +IV R L E S + L ++A D G + + +++ + D
Sbjct: 177 ----IEV-RTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISD 231
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY----FIQPSDTDLPF 1093
ND+ P F++ Y + E +L ++ATD D G N + Y + P + F
Sbjct: 232 SNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME-TF 290
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+I G L++ ++D E Y + V A+D G DVNDN P+
Sbjct: 291 KIDSERGHLTLFKQVDYEITKSYEIDVQAQDLG-PNSIPAHCKIIIKVVDVNDNKPEIN- 348
Query: 1154 FDELLEWKHPEADELSNHNFES---VMMIPVYKATIEENAPIGTTVAKVFAN---DTDFI 1207
+ P +E+S + FE + + + +++ G V K+ +
Sbjct: 349 ----INLMSPGKEEIS-YIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKT 403
Query: 1208 GNGNGLILYSLP---QRKNQQNL-------GLPSLSSTAILMVTVADVPDEVEMSDKPVF 1257
N LIL + +++++ +L G PSLS+ V + D+ D + P F
Sbjct: 404 YENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDIND-----NPPHF 458
Query: 1258 ISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNE--NDTDIRRTFVIDPRNG 1313
YE I EN + + ++ T+ EN ++ Y IL + I IDP NG
Sbjct: 459 QRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNG 518
Query: 1314 TLYLVRSPDREVKDTYEVIVRA 1335
+Y +R D E +V A
Sbjct: 519 AIYALRIFDHEEVSQITFVVEA 540
Score = 67.7 bits (158), Expect = 2e-09
Identities = 59/189 (31%), Positives = 86/189 (45%), Gaps = 13/189 (6%)
Query: 716 VRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVI--SGAGIYQ 772
VRF A Q+ + + + ED G I +DRE+ + EF+ + ++
Sbjct: 57 VRFR-AMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFH 115
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
+ + + D NDN P F + I E++ +GT I +D+ A D D G N+L Y+L
Sbjct: 116 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDS---AFDPDVGENSLHTYSLSAN 172
Query: 833 GKEMFDVDENTGVVKF----IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
+V T K+ + LDRE K Y+L L A D G S + L I I D
Sbjct: 173 DFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDS 232
Query: 887 NDNKPEFNQ 895
NDN P F Q
Sbjct: 233 NDNSPAFEQ 241
Score = 66.1 bits (154), Expect = 7e-09
Identities = 61/236 (25%), Positives = 92/236 (38%), Gaps = 22/236 (9%)
Query: 925 NKFALDVDQLGP----LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSK 980
NK ++++ + P + I E PI T + + D DSGLNG+I + + + K
Sbjct: 343 NKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQK 402
Query: 981 LSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDV 1038
+ Y ++ SE+ L + A D G +L+ V + D+
Sbjct: 403 TYEN-----NYLILTN------ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDI 451
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-----FIQPSDTDLPF 1093
ND+ P F+++ Y F + E + V ATD D G+N +TY FI S
Sbjct: 452 NDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYV 511
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
I P G + D E + V ARD G D NDN P
Sbjct: 512 TIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVP 567
Score = 59.3 bits (137), Expect = 8e-07
Identities = 74/299 (24%), Positives = 118/299 (39%), Gaps = 42/299 (14%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE----------------KA 116
G+ Q S + + I D NDN P F Y + + E +P G K
Sbjct: 215 GVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKI 274
Query: 117 FIFLIAPIGPSL--TIPLTVPRG-LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFA 173
+ + P + T + RG LT+FK + D T + ++ V D G +
Sbjct: 275 VYSFSSHVSPKIMETFKIDSERGHLTLFKQV-----DYEITKSYEID---VQAQDLGPNS 326
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI-------DQDLG 226
+ + K ++ KV+D + E + +M+ GK I +PI D+D G
Sbjct: 327 IPAHCKIII---KVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSG 383
Query: 227 VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
+ + +L KL N + LD + + + + L V A P
Sbjct: 384 LNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDRE-----KRSEYSLTVIAEDRGTPSL 438
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ +++ D+NDN P F+ Y I EN G + V ATD D GENG+ TY +
Sbjct: 439 STVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTI 497
Score = 58.8 bits (136), Expect = 1e-06
Identities = 123/575 (21%), Positives = 219/575 (38%), Gaps = 66/575 (11%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP--FAVEERSGV 628
P F + + + +GT +I ++ AF+ DV + LH Y F +E R+
Sbjct: 128 PQFSRSLIPIEISESAAVGT---RIPLDSAFDP-DVGENSLHTYSLSANDFFNIEVRTRT 183
Query: 629 -------ITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAH 681
+ VV +L R + Y+ + A + + + +++ + ++D
Sbjct: 184 DGAKYAELIVVRELDRELKSSYELQLTA--SDMGVPQRSGSSILKISISDSNDNSPAFEQ 241
Query: 682 SPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFT 740
I + ENS + + NG F + + I +E G +
Sbjct: 242 QSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTL 301
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP-----VFEHATYE-G 794
K +D E Y + V A+ + G S ++ I + D NDN P + E
Sbjct: 302 FKQVDYEITKSYEIDVQAQ-DLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEIS 360
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+I E I T + + ++ D D G N + L G G + +LD
Sbjct: 361 YIFEGDPIDTFVAL---VRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLD 417
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
REK+ Y L+++A D G LS+ + I D NDN P F + + E G
Sbjct: 418 REKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVI---SENNSPG 474
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPL-FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
T+ P D+ + G + + I E+ +G++I +D +G +R +
Sbjct: 475 AYITTVTATDP------DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDH 528
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISV 1031
EV S+++ FV+ R G + L + L I +D NDN+ V
Sbjct: 529 EEV----SQIT---------FVVEARDGG--SPKQLVSNTTVVLTI--IDE---NDNVPV 568
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL 1091
+ P + + + + + ++ A D D G NA L+ I + +
Sbjct: 569 VI--------GPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 620
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F I P + + N +D ++ L+V+ +D G
Sbjct: 621 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKG 655
Score = 54.8 bits (126), Expect = 2e-05
Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHY 1285
++G+P S ++IL ++++D D + P F + Y +++ EN L+ LN T+
Sbjct: 213 DMGVPQRSGSSILKISISDSND-----NSPAFEQQSYIIQLLENSPVGTLLLDLNATDPD 267
Query: 1286 E--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
E N K+ Y + I TF ID G L L + D E+ +YE+ V+
Sbjct: 268 EGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQ--------- 318
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
A+D+ K+++++ DVNDN P+
Sbjct: 319 --------AQDLGPNSIPAHCKIIIKVVDVNDNKPE 346
Score = 49.6 bits (113), Expect = 6e-04
Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 10/163 (6%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+T+R+ + + L ++ NG + + +D E Q N ++ + P +
Sbjct: 55 STVRFRAMQRGNSPLLVVNEDNGEISIGATID--REQLCQKN-LNCSIEFDVITLPTEHL 111
Query: 289 QA-RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
Q +E+E+LD+NDN P+F I I E+ G + A D D GEN TY L
Sbjct: 112 QLFHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-S 170
Query: 348 PKGAFSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE 385
F+I+ R+ + + LDRE SS +++ A +
Sbjct: 171 ANDFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASD 213
Score = 46.8 bits (106), Expect = 0.005
Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 14/171 (8%)
Query: 993 VINERHGHVIVARSLPPESEFRLNISA---LDGGNLNDN----ISVRVFVKDVNDHFPVF 1045
V+NE +G + + ++ E + N++ D L + V V D+ND+ P F
Sbjct: 71 VVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQF 130
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT-----G 1100
++ + E+ + A D D G+N+ TY + +D E+ T
Sbjct: 131 SRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDF-FNIEVRTRTDGAKYA 189
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L V ELDRE + Y L + A D G D NDNSP F
Sbjct: 190 ELIVVRELDRELKSSYELQLTASDMG-VPQRSGSSILKISISDSNDNSPAF 239
Score = 44.8 bits (101), Expect = 0.018
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
Query: 218 IHAIDQDLGVGATLRYELIS----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D DLG + Y ++ G+ + ++D NG+++ + D + + TF
Sbjct: 480 VTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQI---TF 536
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLP-----EFEVDFYNISIVENLPNGFSVLQ 327
V++ + L + V + ++D NDN+P + I+I + +GF V +
Sbjct: 537 VVEARDGGSPKQL-VSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTR 595
Query: 328 VMATDKDQGENGEFTYQL--DDPKGAFSIDPRS 358
+ A D+D G N E + + + + F IDPRS
Sbjct: 596 IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRS 628
>UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor
suppressor homolog 4, partial; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to FAT tumor
suppressor homolog 4, partial - Strongylocentrotus
purpuratus
Length = 1282
Score = 105 bits (253), Expect = 7e-21
Identities = 123/466 (26%), Positives = 213/466 (45%), Gaps = 38/466 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + S NV V L+ + P F S+ Y ++ NA GT I +V+A++ D+ G+V
Sbjct: 429 DMECDSVTNVTVRLMP-DGLAPNFTQSS-YLGNVSENAPEGTDIIQVEAINSDMTSEGIV 486
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSL 552
Y LQ S+ F ++ +G VSV E + + + L VEA D+ + RYS+
Sbjct: 487 -YLLQMASDGG-EDVFSVDAESGDVSVVEDGLDAEKVKQYTLIVEAVDERG--TYYRYSI 542
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
V I+VT + P F E + V +SV ++ ND + Y +
Sbjct: 543 TSVIIDVTDVNE----HAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDVDAILEYSI-- 596
Query: 613 GYEEGVPFAVEERSGVITVVDDLSR-YNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVN 670
G G PFA++ ++G I+ L R Y+ V + N + +VT + + D+N
Sbjct: 597 GETAG-PFAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDGTNEDDCLVT---ITLTDIN 652
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D G+ + V EN+ + Q+ + I + +++ + D +
Sbjct: 653 DNAPEFTGGSQA---LSVSENTTDTEMLQVIEA--TDIDEGVNAEIVYVLESPDDGLFSV 707
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
E G ++ P D E Y + + A +K + + VT+ I D NDN PVF
Sbjct: 708 D-NETGMLYAHGPFDYEAVKEYTLVISASDSKFLT----LTTVTVTITDVNDNAPVFISF 762
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFI 849
++E+ +G + + + D +G + + +Y+L G F+V++ TG +K
Sbjct: 763 CLNIEVLED--VGVDDVICTVGAVDDDGDGEDTV-LYSLDPSSGDVPFNVNQLTGEIKTD 819
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
G +LDRE + +Y ++++A D+G LSS + +++ D NDN P F
Sbjct: 820 G-TLDRETEDIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMF 864
Score = 94.3 bits (224), Expect = 2e-17
Identities = 122/462 (26%), Positives = 188/462 (40%), Gaps = 57/462 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN + + A D+D G+N +I Y S P L + E + HG
Sbjct: 667 VSENTTDTEMLQVIEATDIDEGVNAEIVYVLES----PDDGLFSVDNETGMLYA----HG 718
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
E+ L ISA D L +V V + DVND+ PVF N V E
Sbjct: 719 PF----DYEAVKEYTLVISASDSKFLTLT-TVTVTITDVNDNAPVFISFCLNIEVLEDVG 773
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
V+ V A D D + Y + PS D+PF ++ LTG + +G LDRETED YI+T
Sbjct: 774 VDDVICTVGAVDDDGDGEDTVLYSLDPSSGDVPFNVNQLTGEIKTDGTLDRETEDIYIIT 833
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMI 1179
++A D+G DVNDN P F + + D+L+ + +++
Sbjct: 834 IIAEDSG-EPPLSSNTTITVIVLDVNDNIPMFAKTSITVRL---QTDDLA----DPPVLL 885
Query: 1180 PVYKATIEENAPIGTTVAKVFANDTDFI---GNGNGLILYS---LPQRK----------N 1223
KAT ++ AP T + + F+ G +Y+ LP N
Sbjct: 886 SRVKATDDDLAPWNITQCEKTGGEDSFVVLTGQDGSCEIYAYEELPLSTDPYSVSFYAFN 945
Query: 1224 QQNLGLPSLSSTAILMV--TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL 1281
N PS + T + + TV DV E E D + + + E+E NV PV V+LN+
Sbjct: 946 PDNRDRPSANVTLTVDIRDTVCDVTFENEADDDVIVL----KSELETNV--PV--VTLNV 997
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
T + + + + D + +++ R D EV +T EV + + +
Sbjct: 998 TSNCNSDDITGEVF-PTDIVMEGKYILLVR-----AYNQSDPEVSETTEVTIVVTGENTA 1051
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
Y V D+ E + + + DV ++P F NG
Sbjct: 1052 PAFEEPFYTV--DITEDSMTMVIDLGPEVTDV--DTPSFANG 1089
Score = 74.9 bits (176), Expect = 2e-11
Identities = 113/453 (24%), Positives = 188/453 (41%), Gaps = 60/453 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P GT II++ A++ D G VY+ ++++D E F ++ G
Sbjct: 460 VSENAPEGTDIIQVEAINSDMTSEGI--------VYL--LQMASDGGE--DVFSVDAESG 507
Query: 1000 HV-IVARSLPPES--EFRLNISALD--GGNLNDNI-SVRVFVKDVNDHFPVFKKTWYNFN 1053
V +V L E ++ L + A+D G +I SV + V DVN+H P F + +
Sbjct: 508 DVSVVEDGLDAEKVKQYTLIVEAVDERGTYYRYSITSVIIDVTDVNEHAPTFAEGVVEVD 567
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR-ET 1112
+EE T + V A D D +A L Y I +T PF I TG +S +G LDR E
Sbjct: 568 IEEEVPTDSSVYTVQANDLDV--DAILEYSI--GETAGPFAIDSKTGEISTDGRLDRDEG 623
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
Y +TVV D D+NDN+P+F + L +S +
Sbjct: 624 TTAYNITVVVMDG----TNEDDCLVTITLTDINDNAPEFTGGSQAL--------SVSENT 671
Query: 1173 FESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLP---QRKNQQNLG 1228
++ M+ + I+E +D F + N G++ P + + L
Sbjct: 672 TDTEMLQVIEATDIDEGVNAEIVYVLESPDDGLFSVDNETGMLYAHGPFDYEAVKEYTLV 731
Query: 1229 LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN-LTEHYEN 1287
+ + S + + TV +V + PVFIS +E+ E+V + ++ + + +
Sbjct: 732 ISASDSKFLTLTTVTVTITDVN-DNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDDGDG 790
Query: 1288 FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHM 1347
Y L+ + D+ F ++ G + + DRE +D Y + +
Sbjct: 791 EDTVLYSLDPSSGDV--PFNVNQLTGEIKTDGTLDRETEDIYIITI-------------- 834
Query: 1348 IYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+AED E + + V + DVNDN P F
Sbjct: 835 ---IAEDSGEPPLSSNTTITVIVLDVNDNIPMF 864
Score = 65.3 bits (152), Expect = 1e-08
Identities = 49/156 (31%), Positives = 74/156 (47%), Gaps = 11/156 (7%)
Query: 208 IHKEILFPEPIHAID-QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
I +E+ ++ + DL V A L Y + G F++DS G + + LD D E
Sbjct: 568 IEEEVPTDSSVYTVQANDLDVDAILEYSI--GETAGPFAIDSKTGEISTDGRLDRD-EGT 624
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
N V+ + + ++ L T I L D+NDN PEF +S+ EN + +
Sbjct: 625 TAYNITVVVMDGTNEDDCLVT------ITLTDINDNAPEFTGGSQALSVSENTTDTEMLQ 678
Query: 327 QVMATDKDQGENGEFTYQLDDP-KGAFSIDPRSGWL 361
+ ATD D+G N E Y L+ P G FS+D +G L
Sbjct: 679 VIEATDIDEGVNAEIVYVLESPDDGLFSVDNETGML 714
Score = 56.4 bits (130), Expect = 6e-06
Identities = 73/314 (23%), Positives = 124/314 (39%), Gaps = 27/314 (8%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIF 141
SV + + DVN++ P F + V ++E PT + + + ++ F
Sbjct: 544 SVIIDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDVDAILEYSIGETAGPF 603
Query: 142 K-DIRAFDRDKPNTPNSD---VHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
D + + + D Y+I DG ++ L+ + D + EF
Sbjct: 604 AIDSKTGEISTDGRLDRDEGTTAYNITVVVMDG-----TNEDDCLVTITLTDINDNAPEF 658
Query: 198 ---QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
+ S E+L + I A D D GV A + Y L S +D LFS+D+ G L+
Sbjct: 659 TGGSQALSVSENTTDTEML--QVIEATDIDEGVNAEIVYVLESPDDG-LFSVDNETGMLY 715
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
D +A + L + AS T V + + D+NDN P F NI
Sbjct: 716 AHGPFDYEA-----VKEYTLVISASDSKFLTLTT---VTVTITDVNDNAPVFISFCLNIE 767
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDRE 372
++E++ + V A D D Y LD G F+++ +G ++ LDRE
Sbjct: 768 VLEDVGVDDVICTVGAVDDDGDGEDTVLYSLDPSSGDVPFNVNQLTG--EIKTDGTLDRE 825
Query: 373 AHSSLRMKVYAKET 386
+ + A+++
Sbjct: 826 TEDIYIITIIAEDS 839
Score = 54.0 bits (124), Expect = 3e-05
Identities = 89/405 (21%), Positives = 163/405 (40%), Gaps = 38/405 (9%)
Query: 423 DKVGTKTENIEYYDEQ----LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTV 478
+KV T +E DE+ S +V + + D N++ P F + E ++ +
Sbjct: 519 EKVKQYTLIVEAVDERGTYYRYSITSVIIDVTDVNEHAPTFA-EGVVEVDIEEEVPTDSS 577
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV-AESPILEGRHALFVE 537
+ V+A D D+ + ++ Y + T+ PF I+ TG +S EG A +
Sbjct: 578 VYTVQANDLDV--DAILEYSIGETAG-----PFAIDSKTGEISTDGRLDRDEGTTAYNIT 630
Query: 538 ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV 597
+ +VTI +T + P+F G V N + I
Sbjct: 631 VVVMDGTNEDD----CLVTITLT----DINDNAPEFTGGSQALSVSENTTDTEMLQVIEA 682
Query: 598 NDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
D E ++ Y +L ++G+ F+V+ +G++ + ++ V ++
Sbjct: 683 TDIDEGVNAEIVY-VLESPDDGL-FSVDNETGMLYAHGPFDY--EAVKEYTLVISASDSK 738
Query: 656 LSIVTNATVHVVDVNDERGVLLKGA-HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+T TV + DVND V + + ++ V + +G + G+G
Sbjct: 739 FLTLTTVTVTITDVNDNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDD------GDGED 792
Query: 715 NVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
V + L + DV ++ G I T LDRE D+Y +T+IAE + G + +
Sbjct: 793 TVLYSLDPSSGDVPFNVNQLT-GEIKTDGTLDRETEDIYIITIIAE-DSGEPPLSSNTTI 850
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
T+ + D NDN P+F + + + + + +KATD D
Sbjct: 851 TVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSR-VKATDDD 894
Score = 50.4 bits (115), Expect = 4e-04
Identities = 40/157 (25%), Positives = 76/157 (48%), Gaps = 10/157 (6%)
Query: 218 IHAIDQDL-GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ AI+ D+ G ++ S +FS+D+ +G + + ++ LDAE + + L V
Sbjct: 473 VEAINSDMTSEGIVYLLQMASDGGEDVFSVDAESGDVSVVED-GLDAE---KVKQYTLIV 528
Query: 277 QA-SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+A + + + V I++ D+N++ P F + I E +P SV V A D D
Sbjct: 529 EAVDERGTYYRYSITSVIIDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLD- 587
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ Y + + G F+ID ++G ++ + LDR+
Sbjct: 588 -VDAILEYSIGETAGPFAIDSKTGEISTDGR--LDRD 621
Score = 39.5 bits (88), Expect = 0.69
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 1349 YPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQ 1403
Y + V++G + D V + + D+NDN+P+FT G++ L + TT QV++
Sbjct: 627 YNITVVVMDGTNEDDCLVTITLTDINDNAPEFTGGSQALSVSENTTDTEMLQVIE 681
Score = 36.7 bits (81), Expect = 4.9
Identities = 27/119 (22%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D T+ Y L + F+++ + G + + LD + E + +++ +
Sbjct: 781 VGAVDDDGDGEDTVLYSLDPSSGDVPFNVNQLTGEIKTDGTLDRETE-----DIYIITII 835
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI-VENLPNGFSVL-QVMATDKD 334
A P ++ + + +LD+NDN+P F + + ++L + +L +V ATD D
Sbjct: 836 AEDSGEPPLSSNTTITVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSRVKATDDD 894
>UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3;
Danio rerio|Rep: protocadherin 1 gamma 32 - Danio rerio
Length = 961
Score = 105 bits (253), Expect = 7e-21
Identities = 111/454 (24%), Positives = 200/454 (44%), Gaps = 32/454 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + +LD NDN P F+ + ++ N+ GT++ + A D D GQNG + Y + +
Sbjct: 245 VFINILDVNDNAPHFL-NPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTP 303
Query: 505 LTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
++ F ++ TG + V L H + V A D+ P E ++ + I+V
Sbjct: 304 DSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVN-- 361
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I M + + +V +GT + I+V D + +L Y G+PF +
Sbjct: 362 --DNTPEISINMVSSV---ISEDVTLGTVIALIKVKDEDTGKNGEVNLHIPY--GLPFKI 414
Query: 623 EER-SGVITVVDD--LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
G+ T++ D L R Y A + S + + + DVND + +
Sbjct: 415 SSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQ 474
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ--DVTDDIAI-AED 735
++S + EN+A A + + N T + L + V+ + I
Sbjct: 475 PSYS---VDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALGLSVSSYVYINPNS 531
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV--FEHATYE 793
G I+ + D E + ++ V + ++G S + V ++I+D+ND+PP+ + T +
Sbjct: 532 GQIYAIRKFDYEHLNAFQFVVQVQ-DRGTPSQSSNATVHVFIKDQNDHPPILIYPAPTSD 590
Query: 794 G----FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
G FI + IG + N I D D G NA Y++ G EMF +D +TG ++
Sbjct: 591 GTLHFFIPRTASIGHLV---NRITFVDGDSGHNAWLFYSILGPDAEMFHIDAHTGELRTA 647
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ + K ++ L+++ +D G S A + + I
Sbjct: 648 QKLSEEDSKSVFSLNVIVKDNGRPSRSASVAVNI 681
Score = 79.0 bits (186), Expect = 9e-13
Identities = 88/346 (25%), Positives = 151/346 (43%), Gaps = 33/346 (9%)
Query: 1011 SEFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
SE+RL ++A+DGG+ + N +V + + DVND+ P F + E ++ ++
Sbjct: 223 SEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLN 282
Query: 1069 ATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
A+DAD GQN ++Y P F + +TG + V G +D E + +TV+ARD
Sbjct: 283 ASDADHGQNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDK 342
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKF------YAFDELLEWKHPEA-----DELSNHNFE 1174
G DVNDN+P+ E + A DE + N E
Sbjct: 343 G-MPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGE 401
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
+ IP Y + ++P +F D + + + Y++ G P SS
Sbjct: 402 VNLHIP-YGLPFKISSP----YKGLFTLMADGLLDREAVAEYTITVTATDS--GSPPRSS 454
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRY 1292
++ ++DV D + P+F Y ++I EN NAP+ VS + + EN + +
Sbjct: 455 QKSFVLCLSDVND-----NPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISF 509
Query: 1293 YILNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
IL + I+P +G +Y +R D E + ++ +V+ +
Sbjct: 510 SILESEALGLSVSSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQ 555
Score = 78.6 bits (185), Expect = 1e-12
Identities = 72/245 (29%), Positives = 112/245 (45%), Gaps = 22/245 (8%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ ++ +VDVND + ++ + E S AA G F + G ++R
Sbjct: 135 SVSIEIVDVNDN-APQFQSQNTSL-----EVSEAAAPGTSFRLESAHDPDVGVNSLRAYY 188
Query: 721 ANQQDVTD-DIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+Q D I DG+ + KPLDREK YR+ ++ + G +G V I
Sbjct: 189 LSQNDCFILKIDTKSDGSKIPILVLNKPLDREKMSEYRL-ILTAVDGGSAEKSGNSAVFI 247
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----G 831
I D NDN P F + T ++ENS GT + ++ A+DAD G N YT
Sbjct: 248 NILDVNDNAPHFLNPTKRVTLLENSPHGTLV---TLLNASDADHGQNGEISYTFDKYTPD 304
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
++F VD TG ++ G +D E ++ ++++ARD G + + I I D NDN
Sbjct: 305 SVLKLFSVDSVTGEIRVTG-LIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDN 363
Query: 890 KPEFN 894
PE +
Sbjct: 364 TPEIS 368
Score = 75.8 bits (178), Expect = 9e-12
Identities = 72/237 (30%), Positives = 103/237 (43%), Gaps = 28/237 (11%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P FL P EN P GT + LNA D D G NG+I Y F+ Y P S
Sbjct: 250 LDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDK--YTPDS-- 305
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKD 1037
V + F ++ G + V + E + + A D G + + ++++ + D
Sbjct: 306 ------VLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIID 359
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI-S 1096
VND+ P + + E V+ + D D G+N + I LPF+I S
Sbjct: 360 VNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHI---PYGLPFKISS 416
Query: 1097 PLTGV--LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
P G+ L +G LDRE +Y +TV A D+G DVNDN P F
Sbjct: 417 PYKGLFTLMADGLLDREAVAEYTITVTATDSG-SPPRSSQKSFVLCLSDVNDNPPIF 472
Score = 65.3 bits (152), Expect = 1e-08
Identities = 111/469 (23%), Positives = 185/469 (39%), Gaps = 52/469 (11%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
++++DVND L + ENS + + + + + NG + F
Sbjct: 247 INILDVNDNAPHFLNPTKRVTLL---ENSPHGTLVTLLNASDADHGQNGEISYTFDKYTP 303
Query: 724 QDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
V ++ + G I +D E V+ +TV+A +KG+ G + I I D ND
Sbjct: 304 DSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLAR-DKGMPPMEGSCNIKIEIIDVND 362
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKEMFDVDE 841
N P I E+ +GT I + IK D D G N + ++ +G ++ +
Sbjct: 363 NTPEISINMVSSVISEDVTLGTVIAL---IKVKDEDTGKNGEVNLHIPYGLPFKISSPYK 419
Query: 842 NTGVVKFIGDSL-DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEE 898
G+ + D L DRE Y +++ A D+G SS+ ++ + D NDN P F+Q
Sbjct: 420 --GLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQ--P 475
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDL 958
+ V I N ++ V A D D + EN I +I++ AL L
Sbjct: 476 SYSVDIAE----NNAPNAPLLSVS-----ASDPD-------VGENSTISFSILESEALGL 519
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNIS 1018
+S VYI P+ A+ Y +N V V P +
Sbjct: 520 ----------SVSSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRGTPSQSSNATVH 569
Query: 1019 ALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA 1078
+ ND+ + ++ +D +F + ++ ++ D D G NA
Sbjct: 570 VFI-KDQNDHPPILIYPAPTSD-------GTLHFFIPRTASIGHLVNRITFVDGDSGHNA 621
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE-TEDKYILTVVARDNG 1126
L Y I D ++ F I TG L +L E ++ + L V+ +DNG
Sbjct: 622 WLFYSILGPDAEM-FHIDAHTGELRTAQKLSEEDSKSVFSLNVIVKDNG 669
Score = 65.3 bits (152), Expect = 1e-08
Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 12/174 (6%)
Query: 218 IHAIDQDLGVGATLRY---ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y + + KLFS+DSV G + + +D H L A +
Sbjct: 281 LNASDADHGQNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLID----HEL-AKVHDV 335
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A P ++IE++D+NDN PE ++ + I E++ G + + D+D
Sbjct: 336 TVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDED 395
Query: 335 QGENGEFTYQLDDPKG-AFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
G+NGE + P G F I P G T+ +LDREA + + V A ++
Sbjct: 396 TGKNGEVNLHI--PYGLPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDS 447
Score = 64.9 bits (151), Expect = 2e-08
Identities = 96/463 (20%), Positives = 176/463 (38%), Gaps = 32/463 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V + ++D NDN P F N + A GT A DPD+G N + Y L +
Sbjct: 135 SVSIEIVDVNDNAPQFQSQNT-SLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQND 193
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ K + + + V P+ + L + A D + ++ + ++V
Sbjct: 194 CFILKIDTKSDGSKIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDV- 252
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGV 618
+ P F+ + N GT V + +DA + ++SY + V
Sbjct: 253 ------NDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSV 306
Query: 619 --PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGV 675
F+V+ +G I V + ++D +A + + N + ++DVND
Sbjct: 307 LKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPE 366
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ S +I ++ + G I + NG N+ ++
Sbjct: 367 ISINMVSSVI--SEDVTLGTVIA-LIKVKDEDTGKNGEVNLHIPYGLPFKISSPYKGL-- 421
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
T+ LDRE Y +TV A + G + + + D NDNPP+F +Y
Sbjct: 422 FTLMADGLLDREAVAEYTITVTAT-DSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVD 480
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GKEMFD---VDENTGVVKFI 849
I EN+ + + A+D D G N+ +++ G + ++ N+G + I
Sbjct: 481 IAENNAPNAPLLS---VSASDPDVGENSTISFSILESEALGLSVSSYVYINPNSGQIYAI 537
Query: 850 GD-SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+ + + + R T SS A + + I D+ND+ P
Sbjct: 538 RKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPP 580
Score = 61.3 bits (142), Expect = 2e-07
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 18/176 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVN-GS----LFLEKELDLDAEHNLQANTFVL 274
A D D+GV + LR +S ND + +D+ + GS L L K LD + + + + L
Sbjct: 174 AHDPDVGVNS-LRAYYLSQNDCFILKIDTKSDGSKIPILVLNKPLDRE-----KMSEYRL 227
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A + K+ + V I +LD+NDN P F ++++EN P+G V + A+D D
Sbjct: 228 ILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDAD 287
Query: 335 QGENGEFTYQLD--DPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+NGE +Y D P FS+D +G +R ++D E + V A++
Sbjct: 288 HGQNGEISYTFDKYTPDSVLKLFSVDSVTG--EIRVTGLIDHELAKVHDVTVLARD 341
Score = 56.0 bits (129), Expect = 7e-06
Identities = 57/246 (23%), Positives = 103/246 (41%), Gaps = 26/246 (10%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+++ ++D NDN P + N+ + + +GTVI +K D D G+NG V +
Sbjct: 352 NIKIEIIDVNDNTPE-ISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIPYGL 410
Query: 504 NLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEV 559
I+SP+K G ++ +L+ + + V A+D + P + S + +V
Sbjct: 411 PFKISSPYK-----GLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDV 465
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLLHGYEEG 617
+ P P F Y + N + + + D E + +S+ +L G
Sbjct: 466 -----NDNP--PIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALG 518
Query: 618 VPFA----VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVND 671
+ + + SG I + + + F V +Q+ S +NATVHV D ND
Sbjct: 519 LSVSSYVYINPNSGQIYAIRKFDYEHLNAFQF-VVQVQDRGTPSQSSNATVHVFIKDQND 577
Query: 672 ERGVLL 677
+L+
Sbjct: 578 HPPILI 583
Score = 55.6 bits (128), Expect = 1e-05
Identities = 47/164 (28%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + ++ +DRE R+ + + ++ V+I I D NDN P F+
Sbjct: 99 GALVIKETMDREILCGGRLHCHIRIQISLQNPLEMHSVSIEIVDVNDNAPQFQSQNTSLE 158
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGD 851
+ E + GT ++++ A D D G N+L Y L + +D + K +
Sbjct: 159 VSEAAAPGTSFRLES---AHDPDVGVNSLRAYYLSQNDCFILKIDTKSDGSKIPILVLNK 215
Query: 852 SLDREKKIMYKLSLVARDTGGL--SSEAELIIMIGDENDNKPEF 893
LDREK Y+L L A D G S + + I I D NDN P F
Sbjct: 216 PLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHF 259
Score = 54.0 bits (124), Expect = 3e-05
Identities = 68/289 (23%), Positives = 115/289 (39%), Gaps = 16/289 (5%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--API 124
L + G + S +V + I DVNDN P FL+ VT+ E +P G + A
Sbjct: 229 LTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADH 288
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTP---NSDVHYSIVSGNDDGHFALESSHKPV 181
G + I T + T ++ F D + + + +D A + P+
Sbjct: 289 GQNGEISYTFDK-YTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPM 347
Query: 182 --LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELI 236
K+ D D ++ I I +++ I I D+D G + +
Sbjct: 348 EGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIP 407
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
G K+ S +L + LD +A + + V A+ +P +++Q + L
Sbjct: 408 YGLPFKISSPYKGLFTLMADGLLDREA-----VAEYTITVTATDSGSPPRSSQKSFVLCL 462
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
D+NDN P F Y++ I EN +L V A+D D GEN ++ +
Sbjct: 463 SDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSI 511
Score = 51.6 bits (118), Expect = 2e-04
Identities = 69/277 (24%), Positives = 109/277 (39%), Gaps = 36/277 (12%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD- 1088
SV + + DVND+ P F+ + V EA A D D G N+ Y++ +D
Sbjct: 135 SVSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDC 194
Query: 1089 ----TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
D + S + +L +N LDRE +Y L + A D G DV
Sbjct: 195 FILKIDTKSDGSKIP-ILVLNKPLDREKMSEYRLILTAVDGG-SAEKSGNSAVFINILDV 252
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
NDN+P F + P + T+ EN+P GT V + A+D
Sbjct: 253 NDNAPHF--------------------------LNPTKRVTLLENSPHGTLVTLLNASDA 286
Query: 1205 DFIGNGNGLILYSLPQRKNQQNLGLPSLSS-TAILMVTVADVPDEVEMSDKPVFISRYYE 1263
D NG I Y+ + L L S+ S T + VT + ++ D V
Sbjct: 287 DH--GQNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGM 344
Query: 1264 LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDT 1300
+E + N +E++ +N + M +++E+ T
Sbjct: 345 PPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVT 381
Score = 50.0 bits (114), Expect = 5e-04
Identities = 45/164 (27%), Positives = 80/164 (48%), Gaps = 10/164 (6%)
Query: 221 IDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
+ D+ + + +IS ++ K F++D +G+L +++ +D + + + + ++Q S
Sbjct: 69 LGMDIHMIVLRQMRIISESNDKYFNVDLTSGALVIKETMDREILCGGRLHCHI-RIQIS- 126
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
L NPL+ V IE++D+NDN P+F+ ++ + E G S A D D G N
Sbjct: 127 LQNPLEMHS--VSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSL 184
Query: 341 FTYQL-DDPKGAFSIDPRSGW----LTVRNQTVLDREAHSSLRM 379
Y L + ID +S + V N+ LDRE S R+
Sbjct: 185 RAYYLSQNDCFILKIDTKSDGSKIPILVLNKP-LDREKMSEYRL 227
Score = 40.3 bits (90), Expect = 0.40
Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 33/399 (8%)
Query: 8 LNLQPVDREEDAHLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDL 67
LN D ++ + +Y T SV+ S+DS+ ++ L D +
Sbjct: 281 LNASDADHGQNGEI-SYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDV--TV 337
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVP-IFLDTPYHVTVDELTPTGEKAFIFLI-APIG 125
+ G+ + ++ + I DVNDN P I ++ V +++T A I + G
Sbjct: 338 LARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTG 397
Query: 126 PSLTIPLTVPRGLTI-----FKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHK 179
+ + L +P GL +K + D + Y+I V+ D G S
Sbjct: 398 KNGEVNLHIPYGLPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKS 457
Query: 180 PVLLLRKVLDYDA-GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISG 238
VL L V D + V +A + +L + A D D+G +T+ + ++
Sbjct: 458 FVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAPLL---SVSASDPDVGENSTISFSILES 514
Query: 239 NDRKLFSLDSV-----NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
L V +G ++ ++ D EH L A FV+QVQ P +++ A V
Sbjct: 515 EALGLSVSSYVYINPNSGQIYAIRKFDY--EH-LNAFQFVVQVQ--DRGTPSQSSNATVH 569
Query: 294 IELLDLNDNLP------EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+ + D ND+ P + I G V ++ D D G N Y +
Sbjct: 570 VFIKDQNDHPPILIYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSGHNAWLFYSILG 629
Query: 348 PKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
P F ID +G L Q + + ++ S + V K+
Sbjct: 630 PDAEMFHIDAHTGELRTA-QKLSEEDSKSVFSLNVIVKD 667
>UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadherin -
Aedes aegypti (Yellowfever mosquito)
Length = 1727
Score = 105 bits (253), Expect = 7e-21
Identities = 240/996 (24%), Positives = 393/996 (39%), Gaps = 140/996 (14%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + V + D NDN P F ++ YE + N+ VG ++ +++AVD D G G
Sbjct: 244 SMATIVVHIRDQNDNFPEFSKAS-YECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFI 302
Query: 501 RTSNLTITSPFKINPNTGTVSV------AESPILEGRHALFVEASDQPANPSERRYSLAV 554
S +I +NP TG +++ A L +H L +EA D + L V
Sbjct: 303 SLSG-SIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQLVV 361
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSYDL 610
++V + P F+ + YE + N + + DA + +++ +++
Sbjct: 362 HILDVN-------DNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEI 414
Query: 611 LHGYEEGVPFAVEERSGVI---TVVD----DLSRYN-RPMYDFEAVALQENANLSIVTNA 662
+ G + F ++ +SG + T +D +N RP++ + LS
Sbjct: 415 VEGQFKD-NFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPV 473
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
T+HV DVND L HS V EN +G+ I ++ +I +G+ F++
Sbjct: 474 TIHVQDVNDHPPQFL---HSVYTQSVPENLPSGSPILEV-----KAIDKDGSSPNNFIVY 525
Query: 722 N-QQDVTDDIAIAEDGTIF---TQKPLDREKRDV----YRMTVIA-EFNKGVISGAGIYQ 772
Q +D I+ D I T LD + D Y + V+A + G +
Sbjct: 526 RIQSGASDKFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCR 585
Query: 773 VTIYIEDENDNPPVF-EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
V I I+D N+ P F E T I EN+ +GT + A D D+ + Y +
Sbjct: 586 VNISIKDVNNKSPYFLEPGTIS--IRENTPVGTYAYR---LLANDLDK--EPILRYYM-- 636
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
D NT + +L + + Y + + T GL +I ++ E
Sbjct: 637 --------DSNTSEARSEEGALVKLSEYDYLTAFMLNSTDGL---IRVIKLLDREKVEII 685
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTII 951
+ I E+ ++T T TI+ V+ +N IPEN P G TI+
Sbjct: 686 KLGFIVEDIAAEFGKQT---ATTTLTIV-VEDENDNNPKFRNSFYKRSIPENSPHGVTIM 741
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
+ A D+D N IRY P E+ ++ G ++V+ + E
Sbjct: 742 SVVADDMDK--NKTIRYSLEG-----PK-------EITELLHLDMETGEIVVSNKIDYEI 787
Query: 1012 EFRLN--ISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
LN + A D G+ + VF++ D ND+ P F NF V E + +
Sbjct: 788 FPWLNFTVRATDSGHPPRSSLAEVFIQVIDENDNNPYFPIDTTNFTVYENSMIGTRIATI 847
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG- 1126
A D D G +TY I F I P TG+L V LDRE +D Y++ + A DN
Sbjct: 848 QALDPDSGAFGKITYLIDRVSASGKFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQ 907
Query: 1127 ----XXXXXXXXXXXXXXXXDVNDNSP------------KFYAFDE-LLEWKHPEADELS 1169
D NDN+P +F+ E LL K +AD+
Sbjct: 908 FGYLSGESRNAFKQIFISVLDENDNAPIIQVPDGCVQVTEFHDIREPLLVLKATDADDPK 967
Query: 1170 NHN-FESVMMIPVYKATIEENAPIGTTVAKVFANDT--DFIGNGNGLILYSLPQRKNQQN 1226
N +I V + I VA++F++ + +F GN + LI+ ++
Sbjct: 968 TGNGLIGFDIIDVAGSDIFFLRQKERGVAEIFSSRSLNNFYGNYSLLIM--------ARD 1019
Query: 1227 LGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH-- 1284
G P + + + V D D P S + I EN ++ + ++
Sbjct: 1020 EGSPPNTVNEKIDICVLDFNDHAPEFVSP---SSNITIRIPENATVGTMIIQVMARDNDI 1076
Query: 1285 YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
N +RY + R+F ID G++ L DRE + +E+ V A Y + +
Sbjct: 1077 GPNAAVRYR-FKPDPLGSFRSFSIDEDTGSITLKLPLDRERQKVHELRVEA----YDQGI 1131
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
P P++ D+ D+ + VR +VND P+F
Sbjct: 1132 P---TPLSSDL-------DLTIYVR--NVNDYEPQF 1155
Score = 104 bits (250), Expect = 2e-20
Identities = 119/487 (24%), Positives = 207/487 (42%), Gaps = 50/487 (10%)
Query: 443 VNVEVTLL--DANDNNPVFVPSNLYEFSMKSNAKVGTVIG-----KVKAVDPDLGQNGMV 495
V E+T++ D ND P F S+ YE + NA+ T + + + D D G NG
Sbjct: 128 VRTEITIIITDVNDETPTF-RSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTF 186
Query: 496 LYDLQRTSNLTITSPFK-INPNTGTVSVAESPILEGRHALFVEASDQPANPS-ERRYSLA 553
L+ + L +P + +N T + V +S +L+ + + + E ++S+A
Sbjct: 187 DLYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMA 246
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSYD 609
+ + + + + P+F A YE ++ N G+G + QI+ D F + + +
Sbjct: 247 TIVVHI----RDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFI 302
Query: 610 LLHGYEEGVPFAVEERSGVITV-VDDLSRYNRPMYDFEAVALQENANLSI----VTNATV 664
L G + A+ +GVIT+ +R + + ++ NL V
Sbjct: 303 SLSGSIADL-LALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQLVV 361
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
H++DVND V L+ + + EN + + + G ++F I Q
Sbjct: 362 HILDVNDNAPVFLQSMYEA---RLMENKLSFETPLVLEARDADLNGTKNSEIKFEIVEGQ 418
Query: 725 DVTDDIAIAEDGTIFTQKPLDREK--------RDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+ A+ G + P+D E R ++ +TV+A + GV + VTI+
Sbjct: 419 FKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIF-LTVLAS-DSGVPKLSTKVPVTIH 476
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKE 835
++D ND+PP F H+ Y + EN G+ I +KA D D N +Y + +
Sbjct: 477 VQDVNDHPPQFLHSVYTQSVPENLPSGSPILE---VKAIDKDGSSPNNFIVYRIQSGASD 533
Query: 836 MFDVDENTGVVKF-IGDSLDRE----KKIMYKLSLVARDTG----GLSSEAELIIMIGDE 886
F + +TG++ G SLD + K Y L+++A D G L S + I I D
Sbjct: 534 KFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISIKDV 593
Query: 887 NDNKPEF 893
N+ P F
Sbjct: 594 NNKSPYF 600
Score = 98.7 bits (235), Expect = 1e-18
Identities = 132/484 (27%), Positives = 219/484 (45%), Gaps = 55/484 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D D P F+ ++ + +A +GT + +VKA+D D G N + Y + R
Sbjct: 22 VKVKDVEDQPPEFIVASTV-IRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYSISR----N 76
Query: 507 ITSPFKINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
I+SPF+I+ + GT+S E A +E N S+ + + +V T E+T
Sbjct: 77 ISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQN-SKIKPTPSVRT-EITI 134
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQ---NDVSYDLL----H 612
+ P F YE + N T V + N+ F+ ++ ++DL +
Sbjct: 135 IITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTFDLYLEPNN 194
Query: 613 GYEEGVPF-AVEERSGVITVVD----DLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
G E P AV E + V+ V D D + + A + S+ T VH+
Sbjct: 195 GLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMAT-IVVHIR 253
Query: 668 DVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGN-GTGNVRFLIANQQD 725
D ND K ++ ++ ENS GA + QI ++ S G+ GT +RF I+
Sbjct: 254 DQNDNFPEFSKASYE---CYLPENSGVGALLTQIQAVDVDS--GDFGTSGIRF-ISLSGS 307
Query: 726 VTDDIAIAE-DGTIFTQKP----LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ D +A+ G I + P LDRE + +T+ A N G Q+ ++I D
Sbjct: 308 IADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLG-RGNRNSVQLVVHILDV 366
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGT-NALFMYTLF-GEGKEMF 837
NDN PVF + YE +MEN K+ E + +++A DAD GT N+ + + G+ K+ F
Sbjct: 367 NDNAPVFLQSMYEARLMEN-KLSFETPL--VLEARDADLNGTKNSEIKFEIVEGQFKDNF 423
Query: 838 DVDENTG-VVKFIGDSLDREKKIMYK-----LSLVARDTG--GLSSEAELIIMIGDENDN 889
+D +G +V + + L+++A D+G LS++ + I + D ND+
Sbjct: 424 TIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIHVQDVNDH 483
Query: 890 KPEF 893
P+F
Sbjct: 484 PPQF 487
Score = 97.9 bits (233), Expect = 2e-18
Identities = 123/439 (28%), Positives = 194/439 (44%), Gaps = 53/439 (12%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGV 628
P+F+ A V + IGT+V Q++ D N + Y + PF ++ G
Sbjct: 32 PEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYSISRNISS--PFRIDGSLGT 89
Query: 629 ITVVDDLSRY---NRP--MYDFEAVALQENANL----SIVTNATVHVVDVNDERGVLLKG 679
I+ L R NR Y E VA ++N+ + S+ T T+ + DVNDE
Sbjct: 90 ISTTMKLDREDARNRANAAYILEIVATEQNSKIKPTPSVRTEITIIITDVNDETPTFRSH 149
Query: 680 AH-SPIIFHVKENSAGAAIGQIFHTNMSSIYG---NGTGNVRFLIANQQ--DVTDDIAIA 733
++ S I + +EN+ + +G F N Y NGT ++ +L N ++T A+
Sbjct: 150 SYESEINENAQENTPVSFLG--FSRNEVFDYDQGHNGTFDL-YLEPNNGLFEITPSRAVN 206
Query: 734 EDGTIFTQKP---LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
E + K LD EK T+ A + + ++I D+NDN P F A
Sbjct: 207 EATFVLRVKDSTLLDYEKVKSMNFTIHAR-EIAPEGKHSMATIVVHIRDQNDNFPEFSKA 265
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI- 849
+YE ++ ENS +G + + D GT+ + +L G ++ ++ TGV+
Sbjct: 266 SYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFISLSGSIADLLALNPLTGVITIKA 325
Query: 850 --GDSLDREKKIMYKLSLVARDT--GGLSSEAELIIMIGDENDNKPEF-----------N 894
G +LDRE + L++ ARD G + +L++ I D NDN P F N
Sbjct: 326 PGGHALDRELVQKHYLTIEARDNLGRGNRNSVQLVVHILDVNDNAPVFLQSMYEARLMEN 385
Query: 895 QIE-ENSKVRIHRETKLNGTAG----FTIIEVKPKNKFALDV--DQLGPLFLIP-ENIPI 946
++ E V R+ LNGT F I+E + K+ F +D +L PL I E +
Sbjct: 386 KLSFETPLVLEARDADLNGTKNSEIKFEIVEGQFKDNFTIDAKSGKLVPLTPIDFELLTS 445
Query: 947 GTTIIK---LNALDLDSGL 962
GT I+ L L DSG+
Sbjct: 446 GTFNIRPIFLTVLASDSGV 464
Score = 95.1 bits (226), Expect = 1e-17
Identities = 166/721 (23%), Positives = 281/721 (38%), Gaps = 87/721 (12%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
++QL SF V +++ D N+ +P F+ S++ N VGT ++ A D D
Sbjct: 577 EQQLQSFCRVNISIKDVNNKSPYFLEPGT--ISIRENTPVGTYAYRLLANDLDKEPILRY 634
Query: 496 LYD------------LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPA 543
D L + S + F +N G + V + L R + +
Sbjct: 635 YMDSNTSEARSEEGALVKLSEYDYLTAFMLNSTDGLIRVIK---LLDREKVEIIKLGFIV 691
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
+ T +T + + P F + Y+ + N G ++ + +D +
Sbjct: 692 EDIAAEFGKQTATTTLTIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDKN 751
Query: 604 NDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNA 662
+ Y L E ++ +G I V + + P +F A + S +
Sbjct: 752 KTIRYSLEGPKEITELLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEV 811
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ V+D ND + F V ENS G I I + S G + +LI
Sbjct: 812 FIQVIDENDNNPYFPIDTTN---FTVYENSMIGTRIATIQALDPDS---GAFGKITYLI- 864
Query: 722 NQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAG---IYQVTI 775
++ + +I D G + LDREK+D Y + + A + G +SG Q+ I
Sbjct: 865 DRVSASGKFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFI 924
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ DENDN P+ + + E I + ++KATDAD+ G G
Sbjct: 925 SVLDENDNAPIIQVPDGCVQVTEFHDIREPLL---VLKATDADDPKT--------GNGLI 973
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
FD+ + G F +R ++ +R L+IM DE + P N
Sbjct: 974 GFDIIDVAGSDIFFLRQKERGVAEIFS----SRSLNNFYGNYSLLIMARDEG-SPP--NT 1026
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
+ E + + N A V P + + IPEN +GT II++ A
Sbjct: 1027 VNEKIDICV---LDFNDHAPEF---VSPSSNITIR---------IPENATVGTMIIQVMA 1071
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--F 1013
D D G N +RY F D L R F I+E G + + L E +
Sbjct: 1072 RDNDIGPNAAVRYRF-----------KPDPLGSFRSFSIDEDTGSITLKLPLDRERQKVH 1120
Query: 1014 RLNISALDGG---NLNDNISVRVFVKDVNDHFPVF--KKTWYNF--NVEEAQYTRRVLGK 1066
L + A D G L+ ++ + ++V++VND+ P F ++ NF + R++
Sbjct: 1121 ELRVEAYDQGIPTPLSSDLDLTIYVRNVNDYEPQFLVEEISVNFTEHARPGLERRQLPDT 1180
Query: 1067 VDATDADFGQN--ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
+D + D + + YFI + + F + P + +L+V ELDRE+ + L V A +
Sbjct: 1181 IDRDEVDDLDDPPTMVCYFIVYGNENGHFHLDPYSHILTVTKELDRESRSNHTLVVKATE 1240
Query: 1125 N 1125
+
Sbjct: 1241 D 1241
Score = 94.3 bits (224), Expect = 2e-17
Identities = 131/490 (26%), Positives = 205/490 (41%), Gaps = 57/490 (11%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVL 496
+L + V V + + D ND+ P F+ S +Y S+ N G+ I +VKA+D D N ++
Sbjct: 466 KLSTKVPVTIHVQDVNDHPPQFLHS-VYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIV 524
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--------RHALFVEASDQPANPSER 548
Y +Q ++ F I+P+TG +SVA L+ + L V A D +
Sbjct: 525 YRIQSGAS----DKFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQL 580
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
+ S V I + NK P F+ P + N +GT ++ ND ++ + Y
Sbjct: 581 Q-SFCRVNISIK--DVNNKS--PYFL-EPGTISIRENTPVGTYAYRLLANDLDKEPILRY 634
Query: 609 DL----------------LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
+ L Y+ F + G+I V+ L R + +
Sbjct: 635 YMDSNTSEARSEEGALVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDI 694
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGN 711
A T T + V DE K +S + ENS G I + +M N
Sbjct: 695 AAEFGKQTATTTLTIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDK---N 751
Query: 712 GTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
T +R+ + +++T+ + + E G I +D E TV A + G + +
Sbjct: 752 KT--IRYSLEGPKEITELLHLDMETGEIVVSNKIDYEIFPWLNFTVRAT-DSGHPPRSSL 808
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+V I + DENDN P F T + ENS IGT I I+A D D G Y +
Sbjct: 809 AEVFIQVIDENDNNPYFPIDTTNFTVYENSMIGTRIA---TIQALDPDSGAFGKITYLID 865
Query: 831 G-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT---GGLSSEA-----ELII 881
F +D +TG++ + D LDREK+ Y + + A D G LS E+ ++ I
Sbjct: 866 RVSASGKFSIDPDTGLL-VVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFI 924
Query: 882 MIGDENDNKP 891
+ DENDN P
Sbjct: 925 SVLDENDNAP 934
Score = 77.8 bits (183), Expect = 2e-12
Identities = 60/187 (32%), Positives = 87/187 (46%), Gaps = 19/187 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D GV +RY IS N F +D G++ +LD + N ++L++
Sbjct: 56 VKAIDGDRGVNNRIRYS-ISRNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIV 114
Query: 278 ASQLNNPLK-TAQARVEIELL--DLNDNLPEFEVDFYNISIVENLPN-------GFSVLQ 327
A++ N+ +K T R EI ++ D+ND P F Y I EN GFS +
Sbjct: 115 ATEQNSKIKPTPSVRTEITIIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNE 174
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSG------WLTVRNQTVLDREAHSSLRMKV 381
V D DQG NG F L+ G F I P L V++ T+LD E S+ +
Sbjct: 175 VF--DYDQGHNGTFDLYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTI 232
Query: 382 YAKETNP 388
+A+E P
Sbjct: 233 HAREIAP 239
Score = 77.0 bits (181), Expect = 4e-12
Identities = 148/684 (21%), Positives = 261/684 (38%), Gaps = 79/684 (11%)
Query: 766 SGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ G + + ++D D PP F A+ + E++ IGT + +KA D D G N
Sbjct: 13 TNTGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQ---VKAIDGDRGVNNRI 69
Query: 826 MYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD 885
Y++ F +D + G + LDRE D ++ A ++ ++
Sbjct: 70 RYSISRNISSPFRIDGSLGTISTTM-KLDRE------------DARNRANAAYILEIVAT 116
Query: 886 ENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIP 945
E ++K I+ VR + T + + ++++ EN P
Sbjct: 117 EQNSK-----IKPTPSVRTEITIIITDVNDET--PTFRSHSYESEINENAQ-----ENTP 164
Query: 946 IGTTIIKLNAL-DLDSGLNG--QIRYEFNSEVY-IPPSKLSADALEVKRYFVINERHGHV 1001
+ N + D D G NG + E N+ ++ I PS+ +A FV+ + +
Sbjct: 165 VSFLGFSRNEVFDYDQGHNGTFDLYLEPNNGLFEITPSRAVNEAT-----FVLRVKDSTL 219
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
+ + F ++ + + ++ V ++D ND+FP F K Y + E
Sbjct: 220 LDYEKVK-SMNFTIHAREIAPEGKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGVG 278
Query: 1062 RVLGKVDATD---ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG----ELDRETED 1114
+L ++ A D DFG + + S DL ++PLTGV+++ LDRE
Sbjct: 279 ALLTQIQAVDVDSGDFGTSGIRFISLSGSIADL-LALNPLTGVITIKAPGGHALDRELVQ 337
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY-------AFDELLEWKHP---E 1164
K+ LT+ ARDN DVNDN+P F + L ++ P E
Sbjct: 338 KHYLTIEARDN-LGRGNRNSVQLVVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLE 396
Query: 1165 A-DELSNHNFESVMMIPVYKATIEENAPIGTTVAK-VFANDTDFIGNGNGLI-LYSLPQR 1221
A D N S + + + ++N I K V DF +G + +
Sbjct: 397 ARDADLNGTKNSEIKFEIVEGQFKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLT 456
Query: 1222 KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL 1281
+ G+P LS+ + + V DV D P F+ Y + EN+ + ++ +
Sbjct: 457 VLASDSGVPKLSTKVPVTIHVQDVNDH-----PPQFLHSVYTQSVPENLPSGSPILEVKA 511
Query: 1282 TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
+ + +I+ + FVI P G + + + T + +Y
Sbjct: 512 IDK-DGSSPNNFIVYRIQSGASDKFVISPDTGIISVATGASLDPDMT-----DPKTTEYF 565
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFG-YQ 1400
+ + + E L+ +V + IKDVN+ SP F P +I P G Y
Sbjct: 566 LNVLALDGGIGEQQLQSF----CRVNISIKDVNNKSPYFL---EPGTISIRENTPVGTYA 618
Query: 1401 VMQLKGAIGHHPTASRTVRADTDE 1424
L + P + ++T E
Sbjct: 619 YRLLANDLDKEPILRYYMDSNTSE 642
Score = 76.2 bits (179), Expect = 7e-12
Identities = 51/166 (30%), Positives = 81/166 (48%), Gaps = 10/166 (6%)
Query: 221 IDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
+ D+ T+RY L + +L LD G + + ++D + L V+A+
Sbjct: 744 VADDMDKNKTIRYSLEGPKEITELLHLDMETGEIVVSNKIDYEIFPWLN-----FTVRAT 798
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P +++ A V I+++D NDN P F +D N ++ EN G + + A D D G G
Sbjct: 799 DSGHPPRSSLAEVFIQVIDENDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFG 858
Query: 340 EFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ TY +D G FSIDP +G L V + LDRE S + + A
Sbjct: 859 KITYLIDRVSASGKFSIDPDTGLLVVAD--FLDREKQDSYMIVIEA 902
Score = 75.4 bits (177), Expect = 1e-11
Identities = 115/472 (24%), Positives = 201/472 (42%), Gaps = 53/472 (11%)
Query: 445 VEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+++ +LD ND+ P FV PS+ + NA VGT+I +V A D D+G N V Y +
Sbjct: 1031 IDICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRF-KPD 1089
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLAVVTIEVT 560
L F I+ +TG++++ + P+ R H L VEA DQ P+ L + TI V
Sbjct: 1090 PLGSFRSFSIDEDTGSITL-KLPLDRERQKVHELRVEAYDQGI-PTPLSSDLDL-TIYV- 1145
Query: 561 RGTKGNKPD-IPDFMGAPYEFWVGSNVG---IGTSVGQIRVNDAFEQND-VSYDLLHGYE 615
R +P + + + + + + ++ + V+D + V Y +++G E
Sbjct: 1146 RNVNDYEPQFLVEEISVNFTEHARPGLERRQLPDTIDRDEVDDLDDPPTMVCYFIVYGNE 1205
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
G F ++ S ++TV +L R +R + A ++ N T ++++ +
Sbjct: 1206 NG-HFHLDPYSHILTVTKELDRESRSNHTLVVKATEDCIN-------TPPSINLSRPEAI 1257
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
L+ +P +H + A+ + SIY R+ + D +
Sbjct: 1258 ALQKP-TPFKYHQRTTKPTTAVASQY----VSIYD------RYKKSRSFDTPGTEIDIKQ 1306
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVI--SGAGIYQVTIYIEDENDNPPVFEHATYE 793
G + Q D + M ++ + + + +V I+++D NDNPPVF +
Sbjct: 1307 GAVSWQSDADSAPSSLL-MPRFEKYTGQLFYHNDNTLVRVLIHVQDINDNPPVFIQKIFT 1365
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-------EG-----KEMFDVDE 841
G + ++ GT+ + A D D G N Y G EG K F VD
Sbjct: 1366 GGVTTSTVFGTQFLK---LTAIDRDHGANGQVSYYQIGDIKKTLTEGLENVQKPPFLVDR 1422
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
TG V+ D + K + ++A D+ G S EA + I + E D + +F
Sbjct: 1423 RTGAVQLNFDP-QKGMKGYFDFKVLANDSAGHSDEAHVFIYLLRE-DQRVKF 1472
Score = 69.7 bits (163), Expect = 6e-10
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 12/219 (5%)
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPI- 218
HY + D+ + V L+ +LD + F L M + + ++ F P+
Sbjct: 339 HYLTIEARDN---LGRGNRNSVQLVVHILDVNDNAPVF-LQSMYEARLMENKLSFETPLV 394
Query: 219 -HAIDQDLG--VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQANTFV 273
A D DL + +++E++ G + F++D+ +G L +D +
Sbjct: 395 LEARDADLNGTKNSEIKFEIVEGQFKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIF 454
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V AS P + + V I + D+ND+ P+F Y S+ ENLP+G +L+V A DK
Sbjct: 455 LTVLASDSGVPKLSTKVPVTIHVQDVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDK 514
Query: 334 D-QGENGEFTYQLDD-PKGAFSIDPRSGWLTVRNQTVLD 370
D N Y++ F I P +G ++V LD
Sbjct: 515 DGSSPNNFIVYRIQSGASDKFVISPDTGIISVATGASLD 553
Score = 67.7 bits (158), Expect = 2e-09
Identities = 126/504 (25%), Positives = 210/504 (41%), Gaps = 55/504 (10%)
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK 483
K+G E+I + + + + + D NDNNP F ++ Y+ S+ N+ G I V
Sbjct: 686 KLGFIVEDIAAEFGKQTATTTLTIVVEDENDNNPKF-RNSFYKRSIPENSPHGVTIMSVV 744
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQ 541
A D D +N + Y L+ IT ++ TG + V+ E L V A+D
Sbjct: 745 ADDMD--KNKTIRYSLEGPKE--ITELLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDS 800
Query: 542 PANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--ND 599
P R SLA V I+V N P F F V N IGT + I+ D
Sbjct: 801 GHPP---RSSLAEVFIQVIDENDNN----PYFPIDTTNFTVYENSMIGTRIATIQALDPD 853
Query: 600 AFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV 659
+ ++Y L+ F+++ +G++ V D L R + Y + +N +
Sbjct: 854 SGAFGKITY-LIDRVSASGKFSIDPDTGLLVVADFLDREKQDSY-MIVIEAWDNYQFGYL 911
Query: 660 TNAT--------VHVVDVNDERGVLL--KGAHSPIIFH-VKENSAGAAIGQIFHTNMSSI 708
+ + + V+D ND ++ G FH ++E
Sbjct: 912 SGESRNAFKQIFISVLDENDNAPIIQVPDGCVQVTEFHDIREPLLVLKATDADDPKT--- 968
Query: 709 YGNGTGNVRFLIANQQDV----TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
GNG + D+ + +AE IF+ + L+ + Y + ++A ++G
Sbjct: 969 -GNGLIGFDIIDVAGSDIFFLRQKERGVAE---IFSSRSLNNFYGN-YSLLIMAR-DEGS 1022
Query: 765 ISGAGIYQVTIYIEDENDNPPVF--EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
++ I + D ND+ P F + I EN+ +GT I + A D D G N
Sbjct: 1023 PPNTVNEKIDICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQ---VMARDNDIGPN 1079
Query: 823 ALFMYTLFGE---GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSE 876
A Y + F +DE+TG + + LDRE++ +++L + A D G LSS+
Sbjct: 1080 AAVRYRFKPDPLGSFRSFSIDEDTGSIT-LKLPLDRERQKVHELRVEAYDQGIPTPLSSD 1138
Query: 877 AELIIMIGDENDNKPEFNQIEENS 900
+L I + + ND +P+F +EE S
Sbjct: 1139 LDLTIYVRNVNDYEPQF-LVEEIS 1161
Score = 62.5 bits (145), Expect = 9e-08
Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
Query: 265 HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS--IVENLPNG 322
+N N + L + A +P T +++I +LD ND+ PEF NI+ I EN G
Sbjct: 1005 NNFYGN-YSLLIMARDEGSPPNTVNEKIDICVLDFNDHAPEFVSPSSNITIRIPENATVG 1063
Query: 323 FSVLQVMATDKDQGENGEFTYQL-DDPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLR 378
++QVMA D D G N Y+ DP G +FSID +G +T++ +R+ LR
Sbjct: 1064 TMIIQVMARDNDIGPNAAVRYRFKPDPLGSFRSFSIDEDTGSITLKLPLDRERQKVHELR 1123
Query: 379 MKVY 382
++ Y
Sbjct: 1124 VEAY 1127
Score = 60.1 bits (139), Expect = 5e-07
Identities = 120/541 (22%), Positives = 214/541 (39%), Gaps = 68/541 (12%)
Query: 930 DVDQLGPLFLIP------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
DV+ P FL P EN P+GT +L A DLD +RY +S S+ A
Sbjct: 592 DVNNKSPYFLEPGTISIRENTPVGTYAYRLLANDLDK--EPILRYYMDSNTSEARSEEGA 649
Query: 984 DALEVKRY-----FVINERHGHVIVARSLPPESE------FRLNISALDGGNLNDNISVR 1032
+++ Y F++N G + V + L E F + A + G ++
Sbjct: 650 -LVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTATTTLT 708
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-PSDTDL 1091
+ V+D ND+ P F+ ++Y ++ E + V A D D +N + Y ++ P +
Sbjct: 709 IVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMD--KNKTIRYSLEGPKEITE 766
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ TG + V+ ++D E TV A D+G D NDN+P +
Sbjct: 767 LLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVI-DENDNNP-Y 824
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAP-------IGTTVAKVFANDT 1204
+ D +N MI ATI+ P I + +V A+
Sbjct: 825 FPIDT------------TNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGK 872
Query: 1205 DFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
I GL++ + + +Q+ + + + + E + K +FIS
Sbjct: 873 FSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGY--LSGESRNAFKQIFIS----- 925
Query: 1265 EIEENVNAPVELVS---LNLTEHYENFKMRYYILNENDTDIRRTF-------VIDPRNGT 1314
++EN NAP+ V + +TE + + + +L D D +T +ID
Sbjct: 926 VLDENDNAPIIQVPDGCVQVTE-FHDIREPLLVLKATDADDPKTGNGLIGFDIIDVAGSD 984
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
++ +R +R V + + R+ Y + + +A D + K+ + + D N
Sbjct: 985 IFFLRQKERGVAEIFSS--RSLNNFYGN---YSLLIMARDEGSPPNTVNEKIDICVLDFN 1039
Query: 1375 DNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGH-HPTASRTVRADTDELVFFERLSL 1433
D++P+F + + + IP A G ++Q+ P A+ R D L F S+
Sbjct: 1040 DHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRFKPDPLGSFRSFSI 1099
Query: 1434 N 1434
+
Sbjct: 1100 D 1100
Score = 57.6 bits (133), Expect = 2e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F L+S +G + + K LD + ++ F+++ A++ T + +E D NDN
Sbjct: 662 FMLNSTDGLIRVIKLLDREKVEIIKLG-FIVEDIAAEFGKQTATTTLTIVVE--DENDNN 718
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK---GAFSIDPRSGW 360
P+F FY SI EN P+G +++ V+A D D +N Y L+ PK +D +G
Sbjct: 719 PKFRNSFYKRSIPENSPHGVTIMSVVADDMD--KNKTIRYSLEGPKEITELLHLDMETGE 776
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKET 386
+ V N+ +D E L V A ++
Sbjct: 777 IVVSNK--IDYEIFPWLNFTVRATDS 800
Score = 50.0 bits (114), Expect = 5e-04
Identities = 61/277 (22%), Positives = 111/277 (40%), Gaps = 8/277 (2%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT 129
I A + +A ++T+ +ED NDN P F ++ Y ++ E +P G + + + T
Sbjct: 694 IAAEFGKQTATTTLTIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDKNKT 753
Query: 130 IPLTVPRGLTIFKDIRAFDRDKPN-TPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
I ++ G ++ D + ++ + Y I + A +S H P L +V
Sbjct: 754 IRYSL-EGPKEITELLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVF 812
Query: 189 --DYDAGDKEFQLVIMASGKRIHKEILFP---EPIHAIDQDLGVGATLRYELISGNDRKL 243
D D I + +++ + I A+D D G + Y + +
Sbjct: 813 IQVIDENDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGK 872
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVL-QVQASQLNNPLKTAQARVEIELLDLNDN 302
FS+D G L + LD + + + Q L+ + A ++ I +LD NDN
Sbjct: 873 FSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFISVLDENDN 932
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P +V + + E +L + ATD D + G
Sbjct: 933 APIIQVPDGCVQVTEFHDIREPLLVLKATDADDPKTG 969
Score = 46.8 bits (106), Expect = 0.005
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 8/113 (7%)
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
T A + +++ D+ D PEF V I + E+ P G +V QV A D D+G N Y +
Sbjct: 15 TGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYSIS 74
Query: 347 -DPKGAFSIDPRSGWLTVRNQTVLDRE-----AHSSLRMKVYAKETNPSVVGT 393
+ F ID G T+ LDRE A+++ +++ A E N + T
Sbjct: 75 RNISSPFRIDGSLG--TISTTMKLDREDARNRANAAYILEIVATEQNSKIKPT 125
Score = 44.4 bits (100), Expect = 0.024
Identities = 40/173 (23%), Positives = 74/173 (42%), Gaps = 11/173 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLD---SVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
D D G T ++L + LF + +VN + F+ + D + + + A
Sbjct: 177 DYDQGHNGT--FDLYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHA 234
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
++ K + A + + + D NDN PEF Y + EN G + Q+ A D D G+
Sbjct: 235 REIAPEGKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDF 294
Query: 339 GEFTYQLDDPKGA----FSIDPRSGWLTVR--NQTVLDREAHSSLRMKVYAKE 385
G + G+ +++P +G +T++ LDRE + + A++
Sbjct: 295 GTSGIRFISLSGSIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARD 347
Score = 43.6 bits (98), Expect = 0.043
Identities = 75/294 (25%), Positives = 117/294 (39%), Gaps = 46/294 (15%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S+ L +T+Y+ +VND P FL V E G + +P T+ R
Sbjct: 1135 LSSDLDLTIYVRNVNDYEPQFLVEEISVNFTEHARPGLER-----------RQLPDTIDR 1183
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
D D P T V Y IV GN++GHF L+ + +L + K LD ++
Sbjct: 1184 D-------EVDDLDDPPTM---VCYFIVYGNENGHFHLDP-YSHILTVTKELDRESRSNH 1232
Query: 197 FQLVIMASGKRIHK----EILFPEPI----------HAIDQDLGVGATLRYELISGNDRK 242
LV+ A+ I+ + PE I H +Y I +K
Sbjct: 1233 -TLVVKATEDCINTPPSINLSRPEAIALQKPTPFKYHQRTTKPTTAVASQYVSIYDRYKK 1291
Query: 243 LFSLDSVNGSLFLEK-----ELDLD-AEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
S D+ + +++ + D D A +L F + QL RV I +
Sbjct: 1292 SRSFDTPGTEIDIKQGAVSWQSDADSAPSSLLMPRF--EKYTGQLFYHNDNTLVRVLIHV 1349
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT-YQLDDPK 349
D+NDN P F + + + G L++ A D+D G NG+ + YQ+ D K
Sbjct: 1350 QDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSYYQIGDIK 1403
Score = 42.7 bits (96), Expect = 0.075
Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 13/129 (10%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T + Y+++ + V V + + D NDN PVF+ ++ + ++ GT K+ A+D D
Sbjct: 1331 TGQLFYHNDNTL--VRVLIHVQDINDNPPVFI-QKIFTGGVTTSTVFGTQFLKLTAIDRD 1387
Query: 489 LGQNGMVLY----DLQRTSNLTITS----PFKINPNTGTVSVAESPI--LEGRHALFVEA 538
G NG V Y D+++T + + PF ++ TG V + P ++G V A
Sbjct: 1388 HGANGQVSYYQIGDIKKTLTEGLENVQKPPFLVDRRTGAVQLNFDPQKGMKGYFDFKVLA 1447
Query: 539 SDQPANPSE 547
+D + E
Sbjct: 1448 NDSAGHSDE 1456
Score = 38.3 bits (85), Expect = 1.6
Identities = 16/42 (38%), Positives = 29/42 (69%)
Query: 72 AGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+G+ ++S + VT++++DVND+ P FL + Y +V E P+G
Sbjct: 462 SGVPKLSTKVPVTIHVQDVNDHPPQFLHSVYTQSVPENLPSG 503
Score = 36.7 bits (81), Expect = 4.9
Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 71 GAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFL 120
G G Q+ ++ V + I+DVN+ P FL+ P +++ E TP G A+ L
Sbjct: 574 GIGEQQLQSFCRVNISIKDVNNKSPYFLE-PGTISIRENTPVGTYAYRLL 622
Score = 36.7 bits (81), Expect = 4.9
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 13/113 (11%)
Query: 1026 NDNISVRVF--VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
NDN VRV V+D+ND+ PVF + + V + K+ A D D G N ++Y+
Sbjct: 1338 NDNTLVRVLIHVQDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSYY 1397
Query: 1084 ----IQPSDTD-------LPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
I+ + T+ PF + TG + +N + + + + V+A D+
Sbjct: 1398 QIGDIKKTLTEGLENVQKPPFLVDRRTGAVQLNFDPQKGMKGYFDFKVLANDS 1450
>UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadherin
beta 1 precursor (PCDH-beta1); n=1; Gallus gallus|Rep:
PREDICTED: similar to Protocadherin beta 1 precursor
(PCDH-beta1) - Gallus gallus
Length = 926
Score = 105 bits (252), Expect = 9e-21
Identities = 122/471 (25%), Positives = 201/471 (42%), Gaps = 36/471 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + + EV + D ND++PVF P + A G KA D D+G NG+
Sbjct: 194 ENPVQLIRGEVEVRDVNDHSPVF-PQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQN 252
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHA-LFVEASDQPANPSERRYSLA 553
Y L S+ ++ + + V + P+ E R L + A+D + P +
Sbjct: 253 YSLSPNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVR 312
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
VV ++ ++P F YE V N G V ++ D E ++ V Y
Sbjct: 313 VVVLDAN-------DNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFS 365
Query: 612 HGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
E F+++ +G I V +L + ++ V + LS V V DVN
Sbjct: 366 QTTERTRQLFSLDPGTGEIRVRGNLDCEDAKNHEM-VVRATDGGGLSAHCRVHVEVRDVN 424
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG------TGNVRFLIANQQ 724
D ++ V E ++ + + NG + N F +A +
Sbjct: 425 DHSPEF---PEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSHFSLALET 481
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ AE + QKPLDRE++ + + A + G S +G QV + + D NDN
Sbjct: 482 EKRGG-KYAE---LVLQKPLDREEQRELHLVLTAT-DGGSPSRSGTAQVRVVVLDANDNM 536
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLFGEG-KEMFDVDE 841
PVF YE + ENS G + + A D DEG+ + ++ EG +++FD++
Sbjct: 537 PVFSREVYEVRVAENSPPGQLVVR---VSAADPDEGSYGKVRYAFSQTTEGSRQLFDLNA 593
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
++GV++ G LD E+ ++L + A D GGLS+ + + + D NDN PE
Sbjct: 594 DSGVIRVSG-KLDFEEAKSHELVVRATDGGGLSAHCRVHVEVLDVNDNAPE 643
Score = 88.6 bits (210), Expect = 1e-15
Identities = 112/434 (25%), Positives = 178/434 (41%), Gaps = 36/434 (8%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV+ N + Q + I E G A D D G+NG Y + P
Sbjct: 204 VEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQNYSLS-----PN 258
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVF 1034
S S K +++ +++ R L E E L ++A DGG+ + VRV
Sbjct: 259 SHFSLALGRGKD----GDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVV 314
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSD-TDLP 1092
V D ND+ PVF + Y V E +++ +V A D D G N + Y F Q ++ T
Sbjct: 315 VLDANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFSQTTERTRQL 374
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F + P TG + V G LD E + + V A D G DVND+SP+F
Sbjct: 375 FSLDPGTGEIRVRGNLDCEDAKNHEMVVRATDGG---GLSAHCRVHVEVRDVNDHSPEFP 431
Query: 1153 AFDELLEWKHPE-ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGN 1211
D +L+ PE A + E+ V +++ + + + G
Sbjct: 432 EKDVVLD--VPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSHFSLALETEKRGGKYA 489
Query: 1212 GLILYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYY 1262
L+L R+ Q+ L G PS S TA + V V D D + PVF Y
Sbjct: 490 ELVLQKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDANDNM-----PVFSREVY 544
Query: 1263 ELEIEENVNAPVELVSLNLTEHYE-NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
E+ + EN +V ++ + E ++ Y ++ R+ F ++ +G + +
Sbjct: 545 EVRVAENSPPGQLVVRVSAADPDEGSYGKVRYAFSQTTEGSRQLFDLNADSGVIRVSGKL 604
Query: 1322 DREVKDTYEVIVRA 1335
D E ++E++VRA
Sbjct: 605 DFEEAKSHELVVRA 618
Score = 84.6 bits (200), Expect = 2e-14
Identities = 77/284 (27%), Positives = 126/284 (44%), Gaps = 21/284 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA---NLSIVTNATVHVVDVNDERGVL 676
F ++ SGV+TV + L R R E+ AL N + V V DVND V
Sbjct: 158 FRLDPHSGVLTVTETLDR-ERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVF 216
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
++ + E ++ + + NG N + ++ + + +DG
Sbjct: 217 ---PQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQN--YSLSPNSHFSLALGRGKDG 271
Query: 737 TIFT----QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ Q+PLDRE++ + + A + G +G QV + + D NDN PVF Y
Sbjct: 272 DKYAELVLQRPLDREEQRELHLVLTAT-DGGSPPRSGTAQVRVVVLDANDNMPVFSREVY 330
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTGVVKFI 849
E + ENS G + + A D DEG+N Y +++F +D TG ++
Sbjct: 331 EIRVAENSPPGQLVVR---VSAADPDEGSNGKVRYAFSQTTERTRQLFSLDPGTGEIRVR 387
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
G +LD E +++ + A D GGLS+ + + + D ND+ PEF
Sbjct: 388 G-NLDCEDAKNHEMVVRATDGGGLSAHCRVHVEVRDVNDHSPEF 430
Score = 75.8 bits (178), Expect = 9e-12
Identities = 68/238 (28%), Positives = 108/238 (45%), Gaps = 18/238 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV+ N + + + + +PE GT A D D G+NG Y + P
Sbjct: 418 VEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLS-----PN 472
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVF 1034
S S ALE ++ ++ +++ + L E E L ++A DGG+ + VRV
Sbjct: 473 SHFSL-ALETEKR---GGKYAELVLQKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVV 528
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP- 1092
V D ND+ PVF + Y V E +++ +V A D D G + Y F Q ++
Sbjct: 529 VLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYAFSQTTEGSRQL 588
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F+++ +GV+ V+G+LD E + L V A D G DVNDN+P+
Sbjct: 589 FDLNADSGVIRVSGKLDFEEAKSHELVVRATDGG---GLSAHCRVHVEVLDVNDNAPE 643
Score = 74.1 bits (174), Expect = 3e-11
Identities = 50/170 (29%), Positives = 82/170 (48%), Gaps = 7/170 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D+G+ Y L + L +G + E L + Q ++ + A+
Sbjct: 240 AQDEDVGINGLQNYSLSPNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLV-LTAT 298
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ A+V + +LD NDN+P F + Y I + EN P G V++V A D D+G NG
Sbjct: 299 DGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNG 358
Query: 340 E----FTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ F+ + + FS+DP +G + VR LD E + M V A +
Sbjct: 359 KVRYAFSQTTERTRQLFSLDPGTGEIRVRGN--LDCEDAKNHEMVVRATD 406
Score = 71.3 bits (167), Expect = 2e-10
Identities = 83/331 (25%), Positives = 140/331 (42%), Gaps = 39/331 (11%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS--------LT 129
S V V + D NDN+P+F Y + V E +P G+ + ++ P
Sbjct: 306 SGTAQVRVVVLDANDNMPVFSREVYEIRVAENSPPGQ--LVVRVSAADPDEGSNGKVRYA 363
Query: 130 IPLTVPRGLTIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLL 183
T R +F +IR R + ++ H +V D G L + + +
Sbjct: 364 FSQTTERTRQLFSLDPGTGEIRV--RGNLDCEDAKNHEMVVRATDGG--GLSAHCRVHVE 419
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
+R V D+ E +V+ + FP A D+D+G+ Y L S N
Sbjct: 420 VRDVNDHSPEFPEKDVVLDVP-ETASPGTRFPLEA-ARDKDVGINGLQDYSL-SPNSHFS 476
Query: 244 FSLDSVN-----GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+L++ L L+K LD + + L L + A+ +P ++ A+V + +LD
Sbjct: 477 LALETEKRGGKYAELVLQKPLDREEQRELH-----LVLTATDGGSPSRSGTAQVRVVVLD 531
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE----FTYQLDDPKGAFSI 354
NDN+P F + Y + + EN P G V++V A D D+G G+ F+ + + F +
Sbjct: 532 ANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYAFSQTTEGSRQLFDL 591
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ SG + V + LD E S + V A +
Sbjct: 592 NADSGVIRVSGK--LDFEEAKSHELVVRATD 620
Score = 57.6 bits (133), Expect = 2e-06
Identities = 50/178 (28%), Positives = 78/178 (43%), Gaps = 19/178 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G +++++A D D G G++RY F S ++ F +N G
Sbjct: 548 VAENSPPGQLVVRVSAADPDEGSYGKVRYAF-----------SQTTEGSRQLFDLNADSG 596
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V+ L E L + A DGG L+ + V V V DVND+ P + + ++ E
Sbjct: 597 VIRVSGKLDFEEAKSHELVVRATDGGGLSAHCRVHVEVLDVNDNAPEMALSSVSASIPED 656
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRET 1112
R V+ + D D G N I + D+PF ++ L + LDRET
Sbjct: 657 APPRTVVALLSVRDRDSGDNGRTECAI---EGDVPFSLTAAFANHYELRTSAALDRET 711
Score = 56.4 bits (130), Expect = 6e-06
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 11/158 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G +RY + R+LF L++ +G + + +LD + +A + L
Sbjct: 561 VSAADPDEGSYGKVRYAFSQTTEGSRQLFDLNADSGVIRVSGKLDFE-----EAKSHELV 615
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ +A RV +E+LD+NDN PE + + SI E+ P V + D+D
Sbjct: 616 VRATDGGG--LSAHCRVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVRDRDS 673
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDRE 372
G+NG ++ FS+ + +R LDRE
Sbjct: 674 GDNGRTECAIEGDV-PFSLTAAFANHYELRTSAALDRE 710
Score = 54.8 bits (126), Expect = 2e-05
Identities = 55/184 (29%), Positives = 81/184 (44%), Gaps = 16/184 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G +RY +R +LFSLD G + + LD + N + +
Sbjct: 347 VSAADPDEGSNGKVRYAFSQTTERTRQLFSLDPGTGEIRVRGNLDCEDAKNHE-----MV 401
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ +A RV +E+ D+ND+ PEF + + E G A DKD
Sbjct: 402 VRATDGGG--LSAHCRVHVEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDV 459
Query: 336 GENGEFTYQLDDPKGAFSI----DPRSG-WLTVRNQTVLDREAHSSLRMKVYAKE-TNPS 389
G NG Y L P FS+ + R G + + Q LDRE L + + A + +PS
Sbjct: 460 GINGLQDYSL-SPNSHFSLALETEKRGGKYAELVLQKPLDREEQRELHLVLTATDGGSPS 518
Query: 390 VVGT 393
GT
Sbjct: 519 RSGT 522
Score = 49.2 bits (112), Expect = 9e-04
Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 19/240 (7%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+D ND V + + V ENS + + + + G VR+ +
Sbjct: 313 VVVLDANDNMPVFSREVYE---IRVAENSPPGQL--VVRVSAADPDEGSNGKVRYAFSQT 367
Query: 724 QDVTDDIAIAEDGT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ T + + GT I + LD E + M V A G+ + ++ + + D N
Sbjct: 368 TERTRQLFSLDPGTGEIRVRGNLDCEDAKNHEMVVRATDGGGLSAHCRVH---VEVRDVN 424
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
D+ P F + E + GT ++ A D D G N L Y+L ++
Sbjct: 425 DHSPEFPEKDVVLDVPETASPGTRFPLE---AARDKDVGINGLQDYSLSPNSHFSLALET 481
Query: 842 NTGVVKF----IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
K+ + LDRE++ L L A D G S A++ +++ D NDN P F++
Sbjct: 482 EKRGGKYAELVLQKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDANDNMPVFSR 541
Score = 44.8 bits (101), Expect = 0.018
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 19/171 (11%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + LDRE+ + + F + + + + + D ND+ PVF
Sbjct: 165 GVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEMVLD 224
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---------FGEGKEMFDVDENTGVV 846
I E + G ++ KA D D G N L Y+L G GK D D+ +V
Sbjct: 225 ISETASPGLRFPLE---KAQDEDVGINGLQNYSLSPNSHFSLALGRGK---DGDKYAELV 278
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ LDRE++ L L A D G S A++ +++ D NDN P F++
Sbjct: 279 --LQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSR 327
Score = 38.3 bits (85), Expect = 1.6
Identities = 46/174 (26%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Query: 221 IDQDLGVG----ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ QDLG+ A + ++S + F LD +G L + + LD E + +
Sbjct: 131 VAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLD--RERICPHSESCALL 188
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
NP++ R E+E+ D+ND+ P F + I E G A D+D G
Sbjct: 189 FKLFFENPVQLI--RGEVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVG 246
Query: 337 ENGEFTYQLDDPKGAFSIDPRSG-----WLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y L P FS+ G + + Q LDRE L + + A +
Sbjct: 247 INGLQNYSL-SPNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATD 299
>UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF8736, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1582
Score = 105 bits (252), Expect = 9e-21
Identities = 116/419 (27%), Positives = 187/419 (44%), Gaps = 42/419 (10%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
K LDREK + + + A + G +G ++ + + D NDN PVF Y+ I ENS+
Sbjct: 171 KQLDREKEEEMSLLLTA-VDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQ 229
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTL---FGEGKEMFDVDENTGVVKFIGDSLDREKK 858
GT + + ATDAD+G N Y++ ++F VDE G V +G ++D EK
Sbjct: 230 KGTTLTR---VSATDADKGRNGEVSYSVSSTMDSVSDIFTVDEK-GDVILLG-AIDFEKA 284
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTI 918
Y++ + ARD+GGLS +++I+ + D NDN P + + ++ + F++
Sbjct: 285 KYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLISILTKSDNIP-ENSPPNTVIVMFSV 343
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+ N + ++ LF I I T I NA S N ++ E SE +
Sbjct: 344 SDPDSSNNGQMILENPMELF----RITIEITDINDNAPSFAS--NEKV-IEI-SESAVTG 395
Query: 979 SKLSAD-ALEVKRYFVINERHGHVIVARSLPPESEFRLNI-SALDGGNLNDNISVRVFVK 1036
SK + AL+ + + + + SL P F L + DGG +
Sbjct: 396 SKFVLEKALDA-------DIGTNGLQSYSLKPTDNFALKYENQADGGKR---------IS 439
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP--- 1092
DVND+ PVF+++ Y + E + V A DAD+ QNA ++Y ++ S + +P
Sbjct: 440 DVNDNAPVFERSSYQAYIVENNTPGLSIFTVRARDADWNQNARVSYILEESSVNGVPVSS 499
Query: 1093 -FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+S +GV+ D E + V A+D G D NDN P+
Sbjct: 500 YVSVSADSGVVHAVRSFDYEQIKDFQFLVRAQDGG-SPPLSSNVSVRILIQDQNDNPPQ 557
Score = 99 bits (238), Expect = 5e-19
Identities = 73/239 (30%), Positives = 119/239 (49%), Gaps = 19/239 (7%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ TV + D+ND K S I F + E+ A +G F + GT +++ +
Sbjct: 1292 SVTVEITDINDNAPFFEK---SEIRFKISES---AVVGAKFVLQRAVDLDAGTNSLQGYV 1345
Query: 721 ANQQD-VTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
D + DGT + QKPLDRE+ + + + A + G +G Q+ +
Sbjct: 1346 LKPSDHFILKLHNQPDGTKNIEMVLQKPLDREENEFISLALTA-VDGGEPQMSGTMQILV 1404
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGE 832
+ D NDN PVF Y+G I EN+ GT + + A+D D N+ Y++ +
Sbjct: 1405 TVLDANDNAPVFTQPVYKGSIAENAAKGTIVTS---VSASDNDHDLNSKITYSITNTLDD 1461
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+ +F+V+E+ G V+ G LD EKK Y++++ A D GGL+ ++I+ + D NDNKP
Sbjct: 1462 VRRLFEVNEDNGEVRLTGH-LDYEKKRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKP 1519
Score = 89.8 bits (213), Expect = 5e-16
Identities = 75/306 (24%), Positives = 130/306 (42%), Gaps = 27/306 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS----LFLEKELDLDAEHNLQANTFVLQ 275
A+D D+GV Y L + +L +G+ + L K+LD + E + L
Sbjct: 130 AVDADIGVNGLKNYSLKPSDHFQLRMQHHTDGNNKVEMVLHKQLDREKEEEMS-----LL 184
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A P + ++ + +LD+NDN P F Y +I EN G ++ +V ATD D+
Sbjct: 185 LTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQKGTTLTRVSATDADK 244
Query: 336 GENGEFTYQ----LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET----- 386
G NGE +Y +D F++D + + + +D E ++ + A+++
Sbjct: 245 GRNGEVSYSVSSTMDSVSDIFTVDEKGDVILL---GAIDFEKAKYYQIDIEARDSGGLSD 301
Query: 387 NPSVVGTFADSQRIAK-----WRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMS 441
+ V+ D A + + N+P +F + N + E M
Sbjct: 302 SSKVIVDVIDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSDPDSSNNGQMILENPME 361
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ + + D NDN P F SN + +A G+ KA+D D+G NG+ Y L+
Sbjct: 362 LFRITIEITDINDNAPSFA-SNEKVIEISESAVTGSKFVLEKALDADIGTNGLQSYSLKP 420
Query: 502 TSNLTI 507
T N +
Sbjct: 421 TDNFAL 426
Score = 85.0 bits (201), Expect = 1e-14
Identities = 114/475 (24%), Positives = 190/475 (40%), Gaps = 44/475 (9%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+DVND V ++ + I + + G + ++ T+ G V + +++
Sbjct: 203 VTVLDVNDNAPVFVQPVYKAAI--AENSQKGTTLTRVSATDADK---GRNGEVSYSVSST 257
Query: 724 QDVTDDI-AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
D DI + E G + +D EK Y++ + A + G+ + +V + + D ND
Sbjct: 258 MDSVSDIFTVDEKGDVILLGAIDFEKAKYYQIDIEARDSGGLSDSS---KVIVDVIDIND 314
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM-YTLFGEGKEMFDVDE 841
N P+ T I ENS T I M ++ ++ G L LF E+ D+++
Sbjct: 315 NAPLISILTKSDNIPENSPPNTVIVMFSVSDPDSSNNGQMILENPMELFRITIEITDIND 374
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
N EK I S V L + D N + ++
Sbjct: 375 NAP------SFASNEKVIEISESAVTGSKFVLEKALD-----ADIGTNGLQSYSLKPTDN 423
Query: 902 VRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSG 961
+ E + +G G I +V N A ++ I EN G +I + A D D
Sbjct: 424 FALKYENQADG--GKRISDV---NDNAPVFERSSYQAYIVENNTPGLSIFTVRARDADWN 478
Query: 962 LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISA 1019
N ++ Y S + + V Y ++ G V RS E +F+ + A
Sbjct: 479 QNARVSYILEES--------SVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFQFLVRA 530
Query: 1020 LDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR------VLGKVDATD 1071
DGG+ L+ N+SVR+ ++D ND+ P A+ R ++ KV A D
Sbjct: 531 QDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVD 590
Query: 1072 ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D GQNA L+Y +Q + FE+ G + ++ + K L+V+ DNG
Sbjct: 591 VDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNG 645
Score = 81.8 bits (193), Expect = 1e-13
Identities = 105/487 (21%), Positives = 209/487 (42%), Gaps = 43/487 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ Q+ V + VT+LD NDN PVFV +Y+ ++ N++ GT + +V A D D G+NG V
Sbjct: 192 EPQMSGTVKIFVTVLDVNDNAPVFVQP-VYKAAIAENSQKGTTLTRVSATDADKGRNGEV 250
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAV 554
Y + T + +++ F ++ + + + + + + +EA D + + V
Sbjct: 251 SYSVSSTMD-SVSDIFTVDEKGDVILLGAIDFEKAKYYQIDIEARDSGGLSDSSKVIVDV 309
Query: 555 VTIE-----VTRGTKGNKPDIPDFMGAPYEFWVGSNVG--IGTSVGQIRVNDAFEQNDVS 607
+ I ++ TK + +IP+ P V +V ++ GQ+ + + E ++
Sbjct: 310 IDINDNAPLISILTKSD--NIPE-NSPPNTVIVMFSVSDPDSSNNGQMILENPMELFRIT 366
Query: 608 YDLLHGYEEGVPFAVEER---------SGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
++ + FA E+ +G V++ + ++ +L+ N ++
Sbjct: 367 IEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALDADIGTNGLQSYSLKPTDNFAL 426
Query: 659 ----VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+ + DVND V + ++ I V+ N+ G + IF N
Sbjct: 427 KYENQADGGKRISDVNDNAPVFERSSYQAYI--VENNTPGLS---IFTVRARDADWNQNA 481
Query: 715 NVRFLI----ANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG 769
V +++ N V+ +++ A+ G + + D E+ ++ V A+ + G +
Sbjct: 482 RVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFQFLVRAQ-DGGSPPLSS 540
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK---ATDADEGTNALFM 826
V I I+D+NDNPP + G M + + ++ A D D G NA
Sbjct: 541 NVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLS 600
Query: 827 YTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD 885
Y L + +F+V G ++ + D++ + +LS++ D G S A +I+ +
Sbjct: 601 YKLQKATDRALFEVGLQNGEIRTVRQVSDKD-AVKQRLSVIVEDNGQPSRSATVIVNVA- 658
Query: 886 ENDNKPE 892
D+ PE
Sbjct: 659 VADSFPE 665
Score = 80.6 bits (190), Expect = 3e-13
Identities = 136/552 (24%), Positives = 226/552 (40%), Gaps = 75/552 (13%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK-RYFVIN 995
LF I E+ G+ + A+D D G+NG Y + PS D +++ ++
Sbjct: 112 LFEISESAVPGSKFVLDRAVDADIGVNGLKNYS------LKPS----DHFQLRMQHHTDG 161
Query: 996 ERHGHVIVARSLP--PESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYN 1051
+++ + L E E L ++A+DGG + +V++FV DVND+ PVF + Y
Sbjct: 162 NNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYK 221
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL--TGVLSVNGELD 1109
+ E L +V ATDAD G+N ++Y + S D +I + G + + G +D
Sbjct: 222 AAIAENSQKGTTLTRVSATDADKGRNGEVSYSVS-STMDSVSDIFTVDEKGDVILLGAID 280
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF---DELLEWKHPE-- 1164
E Y + + ARD+G D+NDN+P D + E P
Sbjct: 281 FEKAKYYQIDIEARDSG---GLSDSSKVIVDVIDINDNAPLISILTKSDNIPENSPPNTV 337
Query: 1165 ------ADELSNHNFESVMMIP--VYKATIE-----ENAPIGTTVAKVFANDTDFIGNGN 1211
+D S++N + ++ P +++ TIE +NAP + KV +
Sbjct: 338 IVMFSVSDPDSSNNGQMILENPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSK 397
Query: 1212 GLILYSLPQRKNQQNLGLPSLSST---AILMVTVADVPDEV-EMSDK-PVFISRYYELEI 1266
++ +L L SL T A+ AD + +++D PVF Y+ I
Sbjct: 398 FVLEKALDADIGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYI 457
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRY-YILNE---NDTDIRRTFVIDPRNGTLYLVRSPD 1322
EN + + ++ + N R YIL E N + + +G ++ VRS D
Sbjct: 458 VENNTPGLSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFD 517
Query: 1323 REVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK--- 1379
E ++ +VR A+D +V V + I+D NDN P+
Sbjct: 518 YEQIKDFQFLVR-----------------AQDGGSPPLSSNVSVRILIQDQNDNPPQVLY 560
Query: 1380 -FTNGNRPLVTAIPTTAPFGYQVMQLKGA---IGHHPTASRTVRADTDELVFFERLSLNG 1435
G + +P +A GY V ++ G + S ++ TD +F L NG
Sbjct: 561 PVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQ-NG 619
Query: 1436 --LTSPQATDSD 1445
T Q +D D
Sbjct: 620 EIRTVRQVSDKD 631
Score = 74.9 bits (176), Expect = 2e-11
Identities = 86/342 (25%), Positives = 146/342 (42%), Gaps = 31/342 (9%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
++++T+ I D NDN PVF++ I E++ G++ +D +A DAD G N L Y+L
Sbjct: 89 LFRITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLD---RAVDADIGVNGLKNYSL 145
Query: 830 ----FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
+ + D N V + LDREK+ L L A D G +S ++ + +
Sbjct: 146 KPSDHFQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTV 205
Query: 884 GDENDNKPEFNQ------IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPL 937
D NDN P F Q I ENS+ + T+++ T + + +D + +
Sbjct: 206 LDVNDNAPVFVQPVYKAAIAENSQ-KGTTLTRVSATDADKGRNGEVSYSVSSTMDSVSDI 264
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYIPPSKLSADALEVK-RYFVIN 995
F + E +I L A+D + QI E +S SK+ D +++ +I+
Sbjct: 265 FTVDEK----GDVILLGAIDFEKAKYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLIS 320
Query: 996 ERHGHVIVARSLPPESEF-RLNISALDGGNLNDNI--------SVRVFVKDVNDHFPVFK 1046
+ + PP + ++S D N I + + + D+ND+ P F
Sbjct: 321 ILTKSDNIPENSPPNTVIVMFSVSDPDSSNNGQMILENPMELFRITIEITDINDNAPSFA 380
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ E+ T A DAD G N +Y ++P+D
Sbjct: 381 SNEKVIEISESAVTGSKFVLEKALDADIGTNGLQSYSLKPTD 422
Score = 66.5 bits (155), Expect = 5e-09
Identities = 60/219 (27%), Positives = 99/219 (45%), Gaps = 20/219 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN-SEVYIPPSKLSADALEVKRYFVINE 996
F I E+ +G + A+DLD+G N Y S+ +I D
Sbjct: 1314 FKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHFILKLHNQPDGT---------- 1363
Query: 997 RHGHVIVARSLP-PESEF-RLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
++ +++ + L E+EF L ++A+DGG ++ + + V V D ND+ PVF + Y
Sbjct: 1364 KNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYKG 1423
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDR 1110
++ E ++ V A+D D N+ +TY I + D+ FE++ G + + G LD
Sbjct: 1424 SIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVNEDNGEVRLTGHLDY 1483
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
E + Y + V A D+G DVNDN P
Sbjct: 1484 EKKRNYQINVQAVDHG---GLTDSCKVIVDVIDVNDNKP 1519
Score = 63.3 bits (147), Expect = 5e-08
Identities = 62/247 (25%), Positives = 101/247 (40%), Gaps = 20/247 (8%)
Query: 663 TVHVVDVNDERGVLLKGAH-------SPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTG 714
TV + D+ND K A + + + V E A G+ +G I + G
Sbjct: 1178 TVEITDINDN-APNFKNAEKRFEIISAQVSYSVPEEMAKGSLVGNIAQDLGLDVKRFKVG 1236
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
N R + + + + G + ++ +DRE F + + Y VT
Sbjct: 1237 NARVYSGDSMEYIE--LDRDRGVLLIKERIDREALCGEVTPCAVHFQIVLENPMEFYSVT 1294
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
+ I D NDN P FE + I E++ +G + + +A D D GTN+L Y L
Sbjct: 1295 VEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQ---RAVDLDAGTNSLQGYVLKPSDH 1351
Query: 835 EMFDV----DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEND 888
+ + D + + LDRE+ L+L A D G +S ++++ + D ND
Sbjct: 1352 FILKLHNQPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDAND 1411
Query: 889 NKPEFNQ 895
N P F Q
Sbjct: 1412 NAPVFTQ 1418
Score = 62.9 bits (146), Expect = 7e-08
Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 13/147 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT + ++A D D LN +I Y + + +V+R F +NE +G
Sbjct: 1425 IAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLD-----------DVRRLFEVNEDNG 1473
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V + L E + +++N+ A+D G L D+ V V V DVND+ P+ K + + E
Sbjct: 1474 EVRLTGHLDYEKKRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKPMIKIMSKSAIISEN 1533
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFI 1084
V+ ++ D D G+N + FI
Sbjct: 1534 ATPETVVTMINIQDPDSGENGRVQCFI 1560
Score = 61.7 bits (143), Expect = 2e-07
Identities = 54/199 (27%), Positives = 87/199 (43%), Gaps = 19/199 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+++ N P G +I + A D D N ++ Y S + + V Y ++
Sbjct: 820 YIVENNSP-GLSIFTVRARDADWSQNARVSYILEES--------SVNGVPVSSYVSVSAD 870
Query: 998 HGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V RS E +F + A DGG+ L+ N+SVR+ ++D ND+ P
Sbjct: 871 SGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGG 930
Query: 1054 VEEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
A+ R ++ KV A D D GQNA L+Y +Q + FE+ G + +
Sbjct: 931 SMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQ 990
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ + K L+V+ DNG
Sbjct: 991 VSDKDAVKQRLSVIVEDNG 1009
Score = 58.8 bits (136), Expect = 1e-06
Identities = 43/124 (34%), Positives = 62/124 (50%), Gaps = 12/124 (9%)
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG--- 833
I D NDN PVFE ++Y+ +I+EN+ G I ++A DAD NA Y L
Sbjct: 802 ISDVNDNAPVFERSSYQAYIVENNSPGLSI---FTVRARDADWSQNARVSYILEESSVNG 858
Query: 834 ---KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDEND 888
V ++GVV + S D E+ + + A+D G LSS + I+I D+ND
Sbjct: 859 VPVSSYVSVSADSGVVHAV-RSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQND 917
Query: 889 NKPE 892
N P+
Sbjct: 918 NPPQ 921
Score = 56.4 bits (130), Expect = 6e-06
Identities = 58/252 (23%), Positives = 104/252 (41%), Gaps = 9/252 (3%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E M F +V V + D NDN P F S + F + +A VG +AVD D G N +
Sbjct: 1285 ENPMEFYSVTVEITDINDNAPFFEKSEI-RFKISESAVVGAKFVLQRAVDLDAGTNSLQG 1343
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
Y L+ + + + + + V + P L+ F+ + + E + S T
Sbjct: 1344 YVLKPSDHFILKLHNQPDGTKNIEMVLQKP-LDREENEFISLALTAVDGGEPQMS---GT 1399
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGY 614
+++ + P F Y+ + N GT V + ND + ++Y + +
Sbjct: 1400 MQILVTVLDANDNAPVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTL 1459
Query: 615 EE-GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
++ F V E +G + + L + Y A+ ++ L+ V V+DVND +
Sbjct: 1460 DDVRRLFEVNEDNGEVRLTGHLDYEKKRNYQINVQAV-DHGGLTDSCKVIVDVIDVNDNK 1518
Query: 674 GVLLKGAHSPII 685
++ + S II
Sbjct: 1519 PMIKIMSKSAII 1530
Score = 55.6 bits (128), Expect = 1e-05
Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 11/170 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSL-DSVNGSLFLEKELDLDAEHNLQANTFV-LQVQ 277
A+D D G + Y ++ +D + L + +G+ +E L + + N F+ L +
Sbjct: 1331 AVDLDAGTNSLQGY-VLKPSDHFILKLHNQPDGTKNIEMVLQKPLDR--EENEFISLALT 1387
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A P + ++ + +LD NDN P F Y SI EN G V V A+D D
Sbjct: 1388 AVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDL 1447
Query: 338 NGEFTYQ----LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N + TY LDD + F ++ +G VR LD E + ++ V A
Sbjct: 1448 NSKITYSITNTLDDVRRLFEVNEDNG--EVRLTGHLDYEKKRNYQINVQA 1495
Score = 55.2 bits (127), Expect = 1e-05
Identities = 59/243 (24%), Positives = 101/243 (41%), Gaps = 20/243 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
E M + V + D NDN+PVF L+E S +A G+ +AVD D+G NG+
Sbjct: 84 ENPMELFRITVEITDINDNSPVFKYEEKLFEIS--ESAVPGSKFVLDRAVDADIGVNGLK 141
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSL 552
Y L+ + + + + N V + E +L + A D +
Sbjct: 142 NYSLKPSDHFQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKI 201
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
V ++V + P F+ Y+ + N GT++ ++ DA + +VSY +
Sbjct: 202 FVTVLDV-------NDNAPVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSV 254
Query: 611 LHGYEE-GVPFAVEERSGVITV-VDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+ F V+E+ VI + D + D EA +++ LS + V V+D
Sbjct: 255 SSTMDSVSDIFTVDEKGDVILLGAIDFEKAKYYQIDIEA---RDSGGLSDSSKVIVDVID 311
Query: 669 VND 671
+ND
Sbjct: 312 IND 314
Score = 54.4 bits (125), Expect = 2e-05
Identities = 55/252 (21%), Positives = 107/252 (42%), Gaps = 17/252 (6%)
Query: 650 LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
+Q + ++ ++ + + DVND V + ++ I V+ NS G +I F
Sbjct: 786 IQSDKSILDEPDSPLEISDVNDNAPVFERSSYQAYI--VENNSPGLSI---FTVRARDAD 840
Query: 710 GNGTGNVRFLI----ANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGV 764
+ V +++ N V+ ++++ D G + + D E+ + V A+
Sbjct: 841 WSQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSP 900
Query: 765 ISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK---ATDADEGT 821
+ + V I I+D+NDNPP + G M + + ++ A D D G
Sbjct: 901 PLSSNV-SVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQ 959
Query: 822 NALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI 880
NA Y L + +F+V G ++ + D++ + +LS++ D G S A +I
Sbjct: 960 NAWLSYKLQKATDRALFEVGLQNGEIRTVRQVSDKD-AVKQRLSVIVEDNGQPSRSATVI 1018
Query: 881 IMIGDENDNKPE 892
+ + D+ PE
Sbjct: 1019 VNVA-VADSFPE 1029
Score = 53.2 bits (122), Expect = 5e-05
Identities = 51/153 (33%), Positives = 69/153 (45%), Gaps = 27/153 (17%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHY 1285
G P +S T ++VTV D D PVF Y+ I EN V VS + +H
Sbjct: 1392 GEPQMSGTMQILVTVLDANDNA-----PVFTQPVYKGSIAENAAKGTIVTSVSASDNDHD 1446
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N K+ Y I N D D+RR F ++ NG + L D E K Y++ V+A +
Sbjct: 1447 LNSKITYSITNTLD-DVRRLFEVNEDNGEVRLTGHLDYEKKRNYQINVQA--------VD 1497
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
H G+T KV+V + DVNDN P
Sbjct: 1498 H----------GGLTD-SCKVIVDVIDVNDNKP 1519
Score = 53.2 bits (122), Expect = 5e-05
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ Q+ + + VT+LDANDN PVF +Y+ S+ NA GT++ V A D D N +
Sbjct: 1393 EPQMSGTMQILVTVLDANDNAPVFT-QPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKI 1451
Query: 496 LYDLQRTSNLTITSPFKINPNTGTV 520
Y + T + + F++N + G V
Sbjct: 1452 TYSITNTLD-DVRRLFEVNEDNGEV 1475
Score = 52.0 bits (119), Expect = 1e-04
Identities = 72/312 (23%), Positives = 129/312 (41%), Gaps = 37/312 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR--KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + Y + S D +F++D G + L +D + +A + +
Sbjct: 237 VSATDADKGRNGEVSYSVSSTMDSVSDIFTVDE-KGDVILLGAIDFE-----KAKYYQID 290
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
++A + ++V ++++D+NDN P + + +I EN P ++ +D D
Sbjct: 291 IEARDSGG--LSDSSKVIVDVIDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSDPDS 348
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
NG+ L++P F I T+ + D + KV E + S V
Sbjct: 349 SNNGQMI--LENPMELFRI-------TIEITDINDNAPSFASNEKVI--EISESAV--TG 395
Query: 396 DSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDN 455
+ K + TN L+ + D K EN +++ D NDN
Sbjct: 396 SKFVLEKALDADIGTNG-LQSYSLKPTDNFALKYENQADGGKRIS----------DVNDN 444
Query: 456 NPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS--NLTITSPFKI 513
PVF S+ + +++N G I V+A D D QN V Y L+ +S + ++S +
Sbjct: 445 APVFERSSYQAYIVENNTP-GLSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSV 503
Query: 514 NPNTGTVSVAES 525
+ ++G V S
Sbjct: 504 SADSGVVHAVRS 515
Score = 50.8 bits (116), Expect = 3e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 9/124 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D + + + Y + + D R+LF ++ NG + L LD + + N Q N
Sbjct: 1438 VSASDNDHDLNSKITYSITNTLDDVRRLFEVNEDNGEVRLTGHLDYEKKRNYQIN----- 1492
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA +++ T +V ++++D+NDN P ++ + I EN V + D D
Sbjct: 1493 VQA--VDHGGLTDSCKVIVDVIDVNDNKPMIKIMSKSAIISENATPETVVTMINIQDPDS 1550
Query: 336 GENG 339
GENG
Sbjct: 1551 GENG 1554
Score = 48.4 bits (110), Expect = 0.002
Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVP----SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V+V + + D NDN P V P ++ + +A VG ++ KV AVD D GQN
Sbjct: 902 LSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNA 961
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ Y LQ+ ++ + N TV V++ ++ R ++ VE + QP+ + ++
Sbjct: 962 WLSYKLQKATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSATVIVNV 1021
Query: 553 AV 554
AV
Sbjct: 1022 AV 1023
Score = 48.0 bits (109), Expect = 0.002
Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-- 1088
+ V + D+ND+ PVFK F + E+ A DAD G N Y ++PSD
Sbjct: 92 ITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHF 151
Query: 1089 -TDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+ V + ++ +LDRE E++ L + A D G DVND
Sbjct: 152 QLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGG-EPQMSGTVKIFVTVLDVND 210
Query: 1147 NSPKF 1151
N+P F
Sbjct: 211 NAPVF 215
Score = 46.8 bits (106), Expect = 0.005
Identities = 22/54 (40%), Positives = 30/54 (55%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+E+ D+NDN P FE Y IVEN G S+ V A D D +N +Y L++
Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEE 853
Score = 46.0 bits (104), Expect = 0.008
Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 6/121 (4%)
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP- 1092
+ DVND+ PVF+++ Y + E + V A DAD+ QNA ++Y ++ S + +P
Sbjct: 802 ISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGVPV 861
Query: 1093 ---FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+S +GV+ D E + V A+D G D NDN P
Sbjct: 862 SSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGG-SPPLSSNVSVRILIQDQNDNPP 920
Query: 1150 K 1150
+
Sbjct: 921 Q 921
Score = 45.6 bits (103), Expect = 0.011
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
SV V + D+ND+ P F+K+ F + E+ A D D G N+ Y ++PSD
Sbjct: 1292 SVTVEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDH 1351
Query: 1090 DLPFEISPLTGVLSV----NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ + G ++ LDRE E+++I + +G D N
Sbjct: 1352 FILKLHNQPDGTKNIEMVLQKPLDRE-ENEFISLALTAVDGGEPQMSGTMQILVTVLDAN 1410
Query: 1146 DNSPKF 1151
DN+P F
Sbjct: 1411 DNAPVF 1416
Score = 44.4 bits (100), Expect = 0.024
Identities = 51/215 (23%), Positives = 88/215 (40%), Gaps = 15/215 (6%)
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATL----RYELISGNDRKLF 244
++ +K F+++ + +E+ + I QDLG+ + SG+ +
Sbjct: 1190 NFKNAEKRFEIISAQVSYSVPEEMAKGSLVGNIAQDLGLDVKRFKVGNARVYSGDSMEYI 1249
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
LD G L +++ +D +A + + Q L NP++ V +E+ D+NDN P
Sbjct: 1250 ELDRDRGVLLIKERIDREALCG-EVTPCAVHFQIV-LENPMEFYS--VTVEITDINDNAP 1305
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVR 364
FE I E+ G + A D D G N Y L P F + + +
Sbjct: 1306 FFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVL-KPSDHFILKLHNQPDGTK 1364
Query: 365 N-----QTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
N Q LDRE + + + + A + P + GT
Sbjct: 1365 NIEMVLQKPLDREENEFISLALTAVDGGEPQMSGT 1399
Score = 42.7 bits (96), Expect = 0.075
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
P GT + I+ D+ ++ + + + D NDN PVF S+ + +++N+ G I
Sbjct: 777 PSSTGTM-QRIQS-DKSILDEPDSPLEISDVNDNAPVFERSSYQAYIVENNSP-GLSIFT 833
Query: 482 VKAVDPDLGQNGMVLYDLQRTS--NLTITSPFKINPNTGTVSVAES 525
V+A D D QN V Y L+ +S + ++S ++ ++G V S
Sbjct: 834 VRARDADWSQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRS 879
Score = 40.3 bits (90), Expect = 0.40
Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+ +G+ + L+ G L ++ +D + Q L +Q L NP++ R+ +
Sbjct: 39 IFTGDSAEYIELNRDRGVLLVKDRIDREMLCK-QTTPCALHLQII-LENPMELF--RITV 94
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
E+ D+NDN P F+ + I E+ G + A D D G NG Y L
Sbjct: 95 EITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSL 145
Score = 39.9 bits (89), Expect = 0.53
Identities = 91/424 (21%), Positives = 169/424 (39%), Gaps = 49/424 (11%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT 139
+ VTV I D+NDN P F + EK F + A + S ++P + +G
Sbjct: 1174 FFRVTVEITDINDNAPNFKNA-------------EKRFEIISAQV--SYSVPEEMAKGSL 1218
Query: 140 IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL 199
+ + D + + SG+ + L+ + VLL+++ +D +A L
Sbjct: 1219 VGNIAQDLGLDVKRFKVGNAR--VYSGDSMEYIELDRD-RGVLLIKERIDREA------L 1269
Query: 200 VIMASGKRIHKEILFPEPI--HAIDQDL-GVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
+ +H +I+ P+ +++ ++ + + S K+ V L+
Sbjct: 1270 CGEVTPCAVHFQIVLENPMEFYSVTVEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQ 1329
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV 316
+ +DLDA N +VL+ + IE++ L L E +F ++++
Sbjct: 1330 RAVDLDAGTN-SLQGYVLKPSDHFILKLHNQPDGTKNIEMV-LQKPLDREENEFISLALT 1387
Query: 317 E---NLPNGFSVLQVMATDKDQGENGE-FTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
P +Q++ T D +N FT + KG+ + + G + V + + D +
Sbjct: 1388 AVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVY--KGSIAENAAKGTI-VTSVSASDND 1444
Query: 373 AHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENI 432
L K+ TN T D +R+ + E N + T ++ +K N+
Sbjct: 1445 --HDLNSKITYSITN-----TLDDVRRLFEVN----EDNGEVRLTGHLDYEKKRNYQINV 1493
Query: 433 EYYDEQ-LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+ D L V V ++D NDN P+ + + NA TV+ + DPD G+
Sbjct: 1494 QAVDHGGLTDSCKVIVDVIDVNDNKPMIKIMSKSAI-ISENATPETVVTMINIQDPDSGE 1552
Query: 492 NGMV 495
NG V
Sbjct: 1553 NGRV 1556
Score = 39.1 bits (87), Expect = 0.92
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 11/115 (9%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN---- 321
Q F V+A +P ++ V I + D NDN P+ + V + E +P
Sbjct: 520 QIKDFQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADV 579
Query: 322 GFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWL-TVRNQTVLDREA 373
G+ V +V+A D D G+N +Y+L + F + ++G + TVR V D++A
Sbjct: 580 GYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQ--VSDKDA 632
Score = 38.7 bits (86), Expect = 1.2
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 11/115 (9%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN---- 321
Q F V+A +P ++ V I + D NDN P+ + V + E +P
Sbjct: 884 QIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADV 943
Query: 322 GFSVLQVMATDKDQGENGEFTYQLD--DPKGAFSIDPRSGWL-TVRNQTVLDREA 373
G+ V +V+A D D G+N +Y+L + F + ++G + TVR V D++A
Sbjct: 944 GYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQ--VSDKDA 996
Score = 38.7 bits (86), Expect = 1.2
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 13/161 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+D ND V + + I EN+A I + + S + + + I N
Sbjct: 1404 VTVLDANDNAPVFTQPVYKGSI---AENAAKGTI--VTSVSASDNDHDLNSKITYSITNT 1458
Query: 724 -QDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
DV + ED G + LD EK+ Y++ V A + G+ +V + + D N
Sbjct: 1459 LDDVRRLFEVNEDNGEVRLTGHLDYEKKRNYQINVQAVDHGGLTDSC---KVIVDVIDVN 1515
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
DN P+ + + I EN+ T + M NI D D G N
Sbjct: 1516 DNKPMIKIMSKSAIISENATPETVVTMINI---QDPDSGEN 1553
>UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1074
Score = 105 bits (252), Expect = 9e-21
Identities = 126/482 (26%), Positives = 200/482 (41%), Gaps = 38/482 (7%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+ ++ ++VEV + D NDN P F P + N VGT I A D D+G N +
Sbjct: 108 FSKEQFKLIHVEVEVKDINDNTPEF-PRKESSLEISENTAVGTRIPLDFAADDDVGSNYI 166
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYS 551
Y + S+ +I + + V + + +AL + A D +PS R
Sbjct: 167 QSYQISVNSHFSIDVLSRADGVKYAELVLMKELDRETQASYALELVAVDG-GSPS--RTG 223
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
V + V K + P F + + + +GT + + D E ++ +++
Sbjct: 224 TTRVNVRV----KDYNDNSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDE--GLNGEVV 277
Query: 612 HGYEEGVP------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS-IVTNATV 664
+G+ VP F V+ +SG +T+ + ++ Y+F+ A N S V V
Sbjct: 278 YGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVV 337
Query: 665 HVVDVND---ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
V DVND E + + + I ++ E +A + + T+ NG V +
Sbjct: 338 QVQDVNDNAPEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANG--QVHCTLY 395
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
A + I + PLDREK Y +TV+AE + G I Q TI + DEN
Sbjct: 396 GHDHFRLQQAYEDSFMIVSTSPLDREKIPEYNLTVVAE-DLGSPPFRTITQYTIRLTDEN 454
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEGKEM 836
DN PVF YE ++EN+ G I + A D D G N Y L G
Sbjct: 455 DNAPVFSKPVYEVSMVENNAPGAYIA---TVVARDLDTGLNGKVSYKLADSYFMGSPIST 511
Query: 837 F-DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
F +D +G + + S + E +L + A D G LS A + + + D+NDN P
Sbjct: 512 FVSLDPASGSL-YALRSFNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLI 570
Query: 894 NQ 895
Q
Sbjct: 571 TQ 572
Score = 87.0 bits (206), Expect = 3e-15
Identities = 101/458 (22%), Positives = 197/458 (43%), Gaps = 34/458 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V + D NDN+PVF N + + +A VGT++ + A DPD G NG V+Y
Sbjct: 227 VNVRVKDYNDNSPVF-DRNSFSVDLPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVP 285
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRG 562
I F+++ +G +++ E ++ V+A+D NPS ++ + ++V +
Sbjct: 286 TEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSP---AVCKIVVQV-QD 341
Query: 563 TKGNKPDI---PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGV 618
N P+I P ++ + V + +D N + L+G++
Sbjct: 342 VNDNAPEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHDHFR 401
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLL 677
E S +I L R P Y+ VA + +T T+ + D ND V
Sbjct: 402 LQQAYEDSFMIVSTSPLDREKIPEYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFS 461
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA--IAED 735
K + + V+ N+ GA I + ++ + G V + +A+ + I+ ++ D
Sbjct: 462 KPVYE--VSMVENNAPGAYIATVVARDLDT---GLNGKVSYKLADSYFMGSPISTFVSLD 516
Query: 736 ---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF----- 787
G+++ + + E + + A + G +G V + + D+NDN P+
Sbjct: 517 PASGSLYALRSFNYEVMKQLELRITAS-DAGSPPLSGTANVYVKMVDQNDNAPLITQPPL 575
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
+ + E + ++ G + ++A DADEG N+ Y L +F ++++TG +
Sbjct: 576 HNGSAEVLLPRDAPSGYVVTR---VEARDADEGMNSAVSYALAAGELSVFSINKDTGEI- 631
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
++ +L+ + +++ D G L+S A L ++
Sbjct: 632 YLSQALNHDVDQTLSVTVTVSDGGRPALTSTATLHFLV 669
Score = 86.6 bits (205), Expect = 5e-15
Identities = 152/667 (22%), Positives = 270/667 (40%), Gaps = 72/667 (10%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
+E++ G IG + ++S+ G F + Q + + DG + + +DRE+
Sbjct: 33 EEDAPGTVIGNLAR-DISAASSPGISRSNFRMMKQFNSSYVRLRESDGQLSIGERIDRER 91
Query: 749 RDVYRMTVIAEFNKGVISGAG--IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
+ + F+ S + V + ++D NDN P F I EN+ +GT I
Sbjct: 92 ICKHTSQCLIAFDVVSFSKEQFKLIHVEVEVKDINDNTPEFPRKESSLEISENTAVGTRI 151
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+D A D D G+N + Y + DV VK+ E +M +L
Sbjct: 152 PLDF---AADDDVGSNYIQSYQISVNSHFSIDVLSRADGVKYA------ELVLMKELD-- 200
Query: 867 ARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
R+T S EL+ + G N +V+ + + V +N
Sbjct: 201 -RETQA-SYALELVAVDGGSPSRT---GTTRVNVRVKDYNDNS----------PVFDRNS 245
Query: 927 FALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADAL 986
F++D +PE+ P+GT ++ LNA D D GLNG++ Y F +V P+
Sbjct: 246 FSVD---------LPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQV---PT------- 286
Query: 987 EVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-GGNLNDNI-SVRVFVKDVNDHF 1042
E+++ F ++ + G + + + ES+ + ++ A D G N + + + V V+DVND+
Sbjct: 287 EIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNA 346
Query: 1043 PVFKKTWYN------FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
P T + EA + V +D D G N + + D +
Sbjct: 347 PEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHDHFRLQQAY 406
Query: 1097 PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY--AF 1154
+ ++ LDRE +Y LTVVA D G D NDN+P F +
Sbjct: 407 EDSFMIVSTSPLDREKIPEYNLTVVAEDLG-SPPFRTITQYTIRLTDENDNAPVFSKPVY 465
Query: 1155 D-ELLEWKHPEA--DELSNHNFESVMMIPV-YKA--TIEENAPIGTTVAKVFANDTDF-I 1207
+ ++E P A + + ++ + V YK + +PI T V+ A+ + + +
Sbjct: 466 EVSMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYAL 525
Query: 1208 GNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIE 1267
+ N ++ L R + G P LS TA + V + D D + +P + E+ +
Sbjct: 526 RSFNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLP 585
Query: 1268 ENVNAPVELVSLNLTEHYENFKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
+ + + + + E Y L + + F I+ G +YL ++ + +V
Sbjct: 586 RDAPSGYVVTRVEARDADEGMNSAVSYALAAGELSV---FSINKDTGEIYLSQALNHDVD 642
Query: 1327 DTYEVIV 1333
T V V
Sbjct: 643 QTLSVTV 649
Score = 73.3 bits (172), Expect = 5e-11
Identities = 47/175 (26%), Positives = 86/175 (49%), Gaps = 8/175 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G Y++ + + L +G + E L + + QA+ + L++ A
Sbjct: 156 AADDDVGSNYIQSYQISVNSHFSIDVLSRADGVKYAELVLMKELDRETQAS-YALELVAV 214
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P +T RV + + D NDN P F+ + +++ + E+ P G +L + A D D+G NG
Sbjct: 215 DGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEGLNG 274
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
E Y + + F +D +SG LT+ +Q +D E+ ++ V A + P+
Sbjct: 275 EVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQ--IDFESKNTYEFDVQATDLGPN 327
Score = 61.7 bits (143), Expect = 2e-07
Identities = 90/352 (25%), Positives = 136/352 (38%), Gaps = 32/352 (9%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG 125
+LV + G + V V ++D NDN P+F + V + E P G
Sbjct: 210 ELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPD 269
Query: 126 PSLTIPLTVPRGLTIFKDIRAFDR-DKPN---TPNSDVHYSIVSGNDDGHFALESSHKPV 181
L + G + +IR R D+ + T S + + + + A + P
Sbjct: 270 EGLNGEVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPS 329
Query: 182 LLLRKVL----DYDAGDKEFQLVIMAS---GKRIHKEILFPEPIHAI----DQDLGVGAT 230
+ K++ D + E + M S G E E A+ D+D G
Sbjct: 330 PAVCKIVVQVQDVNDNAPEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQ 389
Query: 231 LRYELISGNDRKLFSLDSV-NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+ L G+D F L S + LD E + N L V A L +P
Sbjct: 390 VHCTLY-GHDH--FRLQQAYEDSFMIVSTSPLDREKIPEYN---LTVVAEDLGSPPFRTI 443
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD-- 347
+ I L D NDN P F Y +S+VEN G + V+A D D G NG+ +Y+L D
Sbjct: 444 TQYTIRLTDENDNAPVFSKPVYEVSMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSY 503
Query: 348 ----PKGAF-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
P F S+DP SG L + E L +++ A + +P + GT
Sbjct: 504 FMGSPISTFVSLDPASGSLYALRS--FNYEVMKQLELRITASDAGSPPLSGT 553
Score = 57.2 bits (132), Expect = 3e-06
Identities = 52/197 (26%), Positives = 93/197 (47%), Gaps = 19/197 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ N P G I + A DLD+GLNG++ Y+ ++ Y S +S + ++
Sbjct: 469 MVENNAP-GAYIATVVARDLDTGLNGKVSYKL-ADSYFMGSPIST-------FVSLDPAS 519
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + RS E + L I+A D G+ L+ +V V + D ND+ P+ + +
Sbjct: 520 GSLYALRSFNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGS 579
Query: 1055 EEAQYTR-----RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
E R V+ +V+A DAD G N+ ++Y + + + F I+ TG + ++ L+
Sbjct: 580 AEVLLPRDAPSGYVVTRVEARDADEGMNSAVSYALAAGELSV-FSINKDTGEIYLSQALN 638
Query: 1110 RETEDKYILTVVARDNG 1126
+ + +TV D G
Sbjct: 639 HDVDQTLSVTVTVSDGG 655
Score = 50.8 bits (116), Expect = 3e-04
Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 16/151 (10%)
Query: 220 AIDQDLGVGATLRYELIS----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
A D D G+ + Y+L G+ F SLD +GSL+ + + + L+ L
Sbjct: 484 ARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYALRSFNYEVMKQLE-----L 538
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYN----ISIVENLPNGFSVLQVM 329
++ AS +P + A V ++++D NDN P + +N + + + P+G+ V +V
Sbjct: 539 RITASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVE 598
Query: 330 ATDKDQGENGEFTYQLDDPK-GAFSIDPRSG 359
A D D+G N +Y L + FSI+ +G
Sbjct: 599 ARDADEGMNSAVSYALAAGELSVFSINKDTG 629
Score = 48.4 bits (110), Expect = 0.002
Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 24/165 (14%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G PS + T + V V D D + PVF + +++ E+ L+ LN + E
Sbjct: 217 GSPSRTGTTRVNVRVKDYND-----NSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEG 271
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y ++ T+IR+ F +D ++G L L D E K+TYE V+
Sbjct: 272 LNGEVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQ----------- 320
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA 1390
A D+ + K+VV+++DVNDN+P+ + +TA
Sbjct: 321 ------ATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPMTSITA 359
Score = 46.4 bits (105), Expect = 0.006
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 7/115 (6%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
VE+E+ D+NDN PEF ++ I EN G + A D D G N +YQ+
Sbjct: 118 VEVEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQI-SVNSH 176
Query: 352 FSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE-TNPSVVGTFADSQRI 400
FSID S V+ + LDRE +S +++ A + +PS GT + R+
Sbjct: 177 FSIDVLSRADGVKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRV 231
Score = 41.5 bits (93), Expect = 0.17
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 8/91 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLY----EFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
L NV V ++D NDN P+ L+ E + +A G V+ +V+A D D G N
Sbjct: 550 LSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVEARDADEGMNSA 609
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
V Y L L++ F IN +TG + ++++
Sbjct: 610 VSYAL-AAGELSV---FSINKDTGEIYLSQA 636
>UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG18050;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG18050 - Caenorhabditis
briggsae
Length = 4339
Score = 105 bits (252), Expect = 9e-21
Identities = 94/324 (29%), Positives = 144/324 (44%), Gaps = 31/324 (9%)
Query: 594 QIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN 653
+I DA + +D+ + LL + + F ++E SGV+TV+ L + + F A+ +
Sbjct: 3039 RIAAEDA-DSDDIHFRLLDDFNK--TFEIDEFSGVVTVLKPLD--SESVSSFNLTAIASD 3093
Query: 654 ANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
N V V+D ND K +S + ++ + G + ++ +G T
Sbjct: 3094 GNFEDKAIIVVTVIDKNDNAPTFEKSTYSMKV--MESEAVGYELARL------QAFGGDT 3145
Query: 714 GNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ 772
D +++ A++G + +PLD E R+TVIA+ + G+ + Q
Sbjct: 3146 NETIEYSLKASDHNKFVSLNAQNGVLTLAQPLDFETISTLRLTVIAK-DSGIPPLESVAQ 3204
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FG 831
V I + DENDN P FE Y G + ENSK+G ++ +KA DAD Y L
Sbjct: 3205 VEISVMDENDNAPKFEKEKYTGKVKENSKVGEKVL---TVKAVDADSEHFGAVSYELELI 3261
Query: 832 EGKEMFDVDENTGVVK----------FIGDSLDREKKIMYKLSLVARDTG--GLSSEAEL 879
K D T V I +D EK Y L L+A+D G L SEA L
Sbjct: 3262 ADKASDDSLPTTSVTPPFSINANGDVLINQPIDYEKTKKYNLKLIAKDGGRPPLVSEALL 3321
Query: 880 IIMIGDENDNKPEFNQIEENSKVR 903
I +GDENDN P F+ + V+
Sbjct: 3322 DIHVGDENDNAPVFDDCNMTAVVQ 3345
Score = 100 bits (240), Expect = 3e-19
Identities = 116/483 (24%), Positives = 214/483 (44%), Gaps = 44/483 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F + ++++D ND P FV Y S+ AK G + V A D D +N + Y L
Sbjct: 2489 AFSTLTLSVIDINDKPPFFVLP-FYSTSIPETAKEGDTVLMVSATDED--ENDTIEYSLL 2545
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRH----ALFVEASDQPANPSERRYSLAVVT 556
F ++P GT++V++ LE + +L ++A+D ANP A T
Sbjct: 2546 DGGESQF---FSVHPRQGTITVSKK--LEHKAGVTLSLTIKATDS-ANPPHH----ATTT 2595
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+E+ ++ + +P F + Y F+V + IG VG ++ + E ++V + ++ G E
Sbjct: 2596 VEINVASESVR--VPRFSNSHYLFFVPEDADIGDVVGSVQQMET-EIDEVRFTIVPGSEV 2652
Query: 617 G---VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+PF+VE +G I V L R R + + + +T T+ ++DVND
Sbjct: 2653 SDSLLPFSVERSTGKIIVKSSLDRERRKQWKM-TIRADAAGGVHAITTVTLDILDVNDNA 2711
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
G + + ++ + G ++ IF + +G +RF + N+ +
Sbjct: 2712 PAF-HGDYDKLTIS-EDATVGTSV-TIFSAMDRD--DSPSGRIRFSLVNKDPHFE--MNG 2764
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G + PLDRE +D+Y++ A G + TI + D ND+PP FE ++
Sbjct: 2765 DSGWLTVAAPLDRETQDLYQLIARATDEGGFNTDLSF---TISVNDVNDSPPKFEKDEFD 2821
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
++ S + D IK D ++L ++ G + +F +D ++ + +
Sbjct: 2822 VDLLLPSN-ALILHFD--IKDEDLAPNNHSL-LFISEGNEEGVFWIDSENNLLLKRPEIV 2877
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+ +K+ Y L ++A D G ++ + I + + D K +E K I E+ GT
Sbjct: 2878 ENKKE--YSLKIIAFD-GVFEAKTLVKIHLKSKEDVKTRCPDVE---KTVILPESSKKGT 2931
Query: 914 AGF 916
F
Sbjct: 2932 VVF 2934
Score = 99.1 bits (236), Expect = 8e-19
Identities = 149/635 (23%), Positives = 261/635 (41%), Gaps = 85/635 (13%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++ G + L +R VY+ V + G+ V + I D N++ PV+
Sbjct: 435 SKSGVLRVSSKLSISER-VYKFKVAVSLH-GIQGKKDERDVYVEIVDSNNHSPVWSAKWM 492
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ K G + + ATD DEG N +Y + E F+++ NTG + I
Sbjct: 493 RQAPIPLGKPGDVLLK---VDATDQDEGDNGRVVYKINSEIP--FEINANTGEITLIEVP 547
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
K + +++ A D G S + ++ +N K + K I +E++
Sbjct: 548 T---KSNNWMVTVWAIDLGLPLSRMSALNLMFYKNGTK-----VPAKPKPVIIQESE--- 596
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
NK + + + E+ PIGT + KL + D D+G NG IRY
Sbjct: 597 ------------NKHSPVFSSFPEVVEVTEDAPIGTVVAKLQSSDEDAGYNGLIRYVIQD 644
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSL-------PPESEFRLNISALDGGN- 1024
+S + E+ ++E+ G + VA L E ++ +SA+D G
Sbjct: 645 --------ISGSSHEI---LSVDEQSGEITVASDLTLLMKEKQKVVEIQVKVSAVDAGTP 693
Query: 1025 -LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
+ ++++ +KDVN+H P F + Y + E++ + + K A D D G N + +
Sbjct: 694 VKSATRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFS 753
Query: 1084 IQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
+ + + I P TG++ + LDRE +D + +++A D+G
Sbjct: 754 LGNNGAESSVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDG-DPARITVTNLTITVD 812
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVF-A 1201
DVNDN+P+ ++ + + PE +L + F + + A +E+ + + + + A
Sbjct: 813 DVNDNAPR--CVSQVAKARIPE--DLPHGAFVACL------AAFDEDVGLNSKLKFLLNA 862
Query: 1202 NDTDF-IGNGNGLILYSLP------QRKNQQNL-------GLPSLSSTAILMVTVADVPD 1247
F + + +G +L + P Q+ NL G P LS+T L V + DVP
Sbjct: 863 EKVPFRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVELVDVPH 922
Query: 1248 E---VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRR 1304
+ +E D S Y EI V VE + + + + Y I+ N
Sbjct: 923 KHLAIEFDDVAKEASVYENSEIGTEV-IMVEAKEMGDEQKVKAENLEYRIIGGNGWPY-- 979
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
F ID + GT+ DRE + Y + V A K
Sbjct: 980 -FSID-QKGTVRTTHILDREKRSAYWITVEARDAK 1012
Score = 93.5 bits (222), Expect = 4e-17
Identities = 124/456 (27%), Positives = 202/456 (44%), Gaps = 52/456 (11%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V V ++D+N+++PV+ + + + K G V+ KV A D D G NG V+Y +
Sbjct: 472 DVYVEIVDSNNHSPVWSAKWMRQAPIPLG-KPGDVLLKVDATDQDEGDNGRVVYKI---- 526
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE-VTRG 562
N I PF+IN NTG +++ E P + V A D P R +L ++ + T+
Sbjct: 527 NSEI--PFEINANTGEITLIEVPTKSNNWMVTVWAIDL-GLPLSRMSALNLMFYKNGTKV 583
Query: 563 TKGNKPDI---------PDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDL- 610
KP I P F P V + IGT V +++ + DA + Y +
Sbjct: 584 PAKPKPVIIQESENKHSPVFSSFPEVVEVTEDAPIGTVVAKLQSSDEDAGYNGLIRYVIQ 643
Query: 611 -LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
+ G + +V+E+SG ITV DL+ + + ++ +A +A V
Sbjct: 644 DISGSSHEI-LSVDEQSGEITVASDLTLLMKEKQKVVEIQVKVSA-----VDAGTPVKSA 697
Query: 670 NDERGVLLKGA--HSPIIFHVKENSAGAAIGQ-------IFHTNMSSIYGNGTGNVRFLI 720
+ +K HSP H E S AI + IF + G G ++F +
Sbjct: 698 TRTMKLRIKDVNNHSP---HFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFSL 754
Query: 721 ANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
N + I+I + G I PLDRE++DV+ ++IA + G + + +TI ++D
Sbjct: 755 GNNGAESSVISIEPKTGIIKLLNPLDREEQDVHYFSIIAS-DDGDPARITVTNLTITVDD 813
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
NDN P + I E+ G + + A D D G N+ + L E K F V
Sbjct: 814 VNDNAPRCVSQVAKARIPEDLPHGAFVA---CLAAFDEDVGLNSKLKFLLNAE-KVPFRV 869
Query: 840 DENTGVVKFIGDS----LDREKKIMYKLSLVARDTG 871
D ++G + +G+S LD +K + LS+ D G
Sbjct: 870 DHHSGCL--LGNSPDVPLDYQKTPNFNLSIEVADHG 903
Score = 92.3 bits (219), Expect = 9e-17
Identities = 109/459 (23%), Positives = 211/459 (45%), Gaps = 41/459 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ QL S V V V +LD NDN P F + ++ ++++S +G + ++ AVD D G+N +
Sbjct: 1128 EPQLCSNVVVIVKVLDENDNAPTFTQA-MHHYNVRSK-HIGKLC-RIFAVDIDEGENSHL 1184
Query: 496 LYDLQRTSNLTITSP-FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
Y N+T P F I+ N G + +E+ + +AL ++A+D +PS++ + V
Sbjct: 1185 SY------NVTEGDPRFSIDEN-GNIMTSEAIHSDESYALTLQATDH-GSPSQQFAATRV 1236
Query: 555 VTIEV--TRGTKGNKPDIPDFMG--APYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
V V ++ TK +K P G + Y + +G +VG++ DA + +D+ +++
Sbjct: 1237 VLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKLEATDA-DGDDLWWNI 1295
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
G + V F V + +G + + + R +++ + ++ T + V
Sbjct: 1296 FSGDSDSV-FDVRQDTGQLLLAKKVELLKRGELRLN-ISVTDGQDVDHTT-VIIQVSRQI 1352
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT--D 728
+R + ++ S A+G HT ++ GT + + + + D+ D
Sbjct: 1353 SQRPAFSANRYDTLV------SERVAVGTQIHTLKATGENLGTKPLVYSLFSIDDIAMED 1406
Query: 729 DIAIA-EDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
I + G + +PLD E R V + + N S ++ + + DENDN P
Sbjct: 1407 KIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQQANMKSFS-----KLILEVTDENDNAPY 1461
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTGV 845
F T F+ EN + + + A D D+ N + Y++ G + +F +D ++G
Sbjct: 1462 FVEHTAWAFVDENDSVDDVLA---TVTAFDRDQDDNGIITYSIVSGNEESLFKIDSHSGE 1518
Query: 846 VKFIGDSLDRE-KKIMYKLSLVARDTGGLSSEAELIIMI 883
V+ + +D E + ++ L + A D+ +S + EL + I
Sbjct: 1519 VR-LARLIDPEMQHVVSILRIRASDSATISLKDELTLHI 1556
Score = 86.6 bits (205), Expect = 5e-15
Identities = 135/524 (25%), Positives = 214/524 (40%), Gaps = 37/524 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D N+++P F + Y ++ + K G I K A D D G NG + + L +N
Sbjct: 701 MKLRIKDVNNHSPHFDEPSYY-LAISESEKPGKDIFKATANDFDGGNNGKIKFSLG--NN 757
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+S I P TG + + E + H + ASD +P+ + +T++
Sbjct: 758 GAESSVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDD-GDPARITVTNLTITVDDVND 816
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P + + + ++ G V + D + L E+ VPF V
Sbjct: 817 ------NAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKFLLNAEK-VPFRV 869
Query: 623 EERSGVITVVDD---LSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLK 678
+ SG + L P ++ VA LS V +VDV + + ++
Sbjct: 870 DHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVELVDV-PHKHLAIE 928
Query: 679 GAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
V ENS G + + M N+ + I +I + GT
Sbjct: 929 FDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEYRIIGGNG-WPYFSIDQKGT 987
Query: 738 IFTQKPLDREKRDVYRMTVIA-----EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+ T LDREKR Y +TV A +F K A + V I I D ND+ PV + A Y
Sbjct: 988 VRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRA-VLHVFIRILDRNDHRPVAKSAMY 1046
Query: 793 EGFIMENSKIGTEIKMDNIIKATDAD----EGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
++ENS I ++ATDAD +G L G+ + F +D +G +
Sbjct: 1047 IASVLENSPANVVIVK---VEATDADDIDNDGAAPLTFKIERGDPQSFFRIDLASGYITT 1103
Query: 849 IG-DSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
G LDREK+ ++L + D G L S +I+ + DENDN P F Q + VR
Sbjct: 1104 SGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTFTQAMHHYNVRSK 1163
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTT 949
KL I E + + + +V + P F I EN I T+
Sbjct: 1164 HIGKLCRIFAVDIDEGE-NSHLSYNVTEGDPRFSIDENGNIMTS 1206
Score = 78.6 bits (185), Expect = 1e-12
Identities = 102/486 (20%), Positives = 192/486 (39%), Gaps = 45/486 (9%)
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK 483
K G NI D Q + V + + P F +N Y+ + VGT I +K
Sbjct: 1323 KRGELRLNISVTDGQDVDHTTVIIQVSRQISQRPAF-SANRYDTLVSERVAVGTQIHTLK 1381
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPA 543
A +LG +V Y L ++ + ++ P++G V V E E + Q A
Sbjct: 1382 ATGENLGTKPLV-YSLFSIDDIAMEDKIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQQA 1440
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
N S + + +EVT + P F+ +V N + + + D +
Sbjct: 1441 NMK----SFSKLILEVT----DENDNAPYFVEHTAWAFVDENDSVDDVLATVTAFDRDQD 1492
Query: 604 ND--VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
++ ++Y ++ G EE + F ++ SG + + + + + + ++A +S+
Sbjct: 1493 DNGIITYSIVSGNEESL-FKIDSHSGEVRLARLIDPEMQHVVSILRIRASDSATISLKDE 1551
Query: 662 ATVHVVD--VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
T+H+ + E + + + + + H G + F
Sbjct: 1552 LTLHIKSSKLTSENAKFDRKVYQTSLHDSTRPGTPVLVLNVLHH----------GAITFK 1601
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG---IYQVTIY 776
+ D ++ G + K + +EK+ E V++G G ++
Sbjct: 1602 LEPNCTFFDVHTLS--GAVHLAKWITKEKQ-----LKTLECTAYVVNGDGQQDTAKIVAK 1654
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDN----IIKATDADEGTNALFMYTLFGE 832
I N + PVF Y G + EN + G+ + + ++ A+D D G+N L Y + +
Sbjct: 1655 IIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSGSNGLVGYRMLSK 1714
Query: 833 G-KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE----AELIIMIGDEN 887
+EMF VD+ +G V+ + D EK + + A D G + A +++ I DEN
Sbjct: 1715 ADEEMFTVDQYSGAVR-TNKAFDFEKIKEHSFYVQAFDMGQPPRQSLMPALVVVTISDEN 1773
Query: 888 DNKPEF 893
D P+F
Sbjct: 1774 DETPKF 1779
Score = 75.4 bits (177), Expect = 1e-11
Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 4/166 (2%)
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISAL-DGGNLNDNISVRVFVKDVNDHFPVF 1045
+ + F I+E G V V + L ES N++A+ GN D + V V D ND+ P F
Sbjct: 3057 DFNKTFEIDEFSGVVTVLKPLDSESVSSFNLTAIASDGNFEDKAIIVVTVIDKNDNAPTF 3116
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
+K+ Y+ V E++ L ++ A D N + Y ++ SD + ++ GVL++
Sbjct: 3117 EKSTYSMKVMESEAVGYELARLQAFGGD--TNETIEYSLKASDHNKFVSLNAQNGVLTLA 3174
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD ET LTV+A+D+G D NDN+PKF
Sbjct: 3175 QPLDFETISTLRLTVIAKDSG-IPPLESVAQVEISVMDENDNAPKF 3219
Score = 74.9 bits (176), Expect = 2e-11
Identities = 98/461 (21%), Positives = 184/461 (39%), Gaps = 39/461 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLY---EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
+ V + + NDN P ++Y E ++ ++ + ++ A D D L D
Sbjct: 3000 ITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSRQYLTRIAAEDADSDDIHFRLLD--- 3056
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
F+I+ +G V+V + E + + A N ++ A++ + V
Sbjct: 3057 ----DFNKTFEIDEFSGVVTVLKPLDSESVSSFNLTAIASDGNFEDK----AIIVVTVI- 3107
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
+ P F + Y V + +G + +++ + Y L + +
Sbjct: 3108 ---DKNDNAPTFEKSTYSMKVMESEAVGYELARLQAFGGDTNETIEYSL-KASDHNKFVS 3163
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGA 680
+ ++GV+T+ L +A L V + V+D ND K
Sbjct: 3164 LNAQNGVLTLAQPLDFETISTLRLTVIAKDSGIPPLESVAQVEISVMDENDNAPKFEKEK 3223
Query: 681 HSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--------VTDDIA 731
++ VKENS G + + + S + LIA++ VT +
Sbjct: 3224 YTG---KVKENSKVGEKVLTVKAVDADSEHFGAVSYELELIADKASDDSLPTTSVTPPFS 3280
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
I +G + +P+D EK Y + +IA+ + G + I++ DENDN PVF+
Sbjct: 3281 INANGDVLINQPIDYEKTKKYNLKLIAK-DGGRPPLVSEALLDIHVGDENDNAPVFDDCN 3339
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTN-ALFMYTLFGEGKEMFDVDENTGVVKFIG 850
+ E IG ++ +I +D D TN A F + G+G + F V++ ++
Sbjct: 3340 MTAVVQEGESIGHKVLKFSI---SDLDGPTNGAPFTVEIQGDGAKSFKVNDKLELL--TA 3394
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
L+ K Y L+++A+DT G S++ L + I + + P
Sbjct: 3395 KKLEHRNKDKYLLTVIAKDTKGKSTDCPLTVFIRQASRHAP 3435
Score = 72.9 bits (171), Expect = 6e-11
Identities = 42/160 (26%), Positives = 82/160 (51%), Gaps = 7/160 (4%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ + D+D G +RY + ISG+ ++ S+D +G + + +L L + + ++
Sbjct: 625 LQSSDEDAGYNGLIRYVIQDISGSSHEILSVDEQSGEITVASDLTLLMKEKQKVVEIQVK 684
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A P+K+A +++ + D+N++ P F+ Y ++I E+ G + + A D D
Sbjct: 685 VSAVDAGTPVKSATRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDG 744
Query: 336 GENGEFTYQLDD---PKGAFSIDPRSGWLTVRNQTVLDRE 372
G NG+ + L + SI+P++G + + N LDRE
Sbjct: 745 GNNGKIKFSLGNNGAESSVISIEPKTGIIKLLNP--LDRE 782
Score = 70.5 bits (165), Expect = 3e-10
Identities = 110/457 (24%), Positives = 186/457 (40%), Gaps = 40/457 (8%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D ++ N+ +T+ D NDN P V S + + + + G + + A D D+G N +
Sbjct: 798 DPARITVTNLTITVDDVNDNAPRCV-SQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKL 856
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESP--ILEGRHALFVEASDQPANPSERRYSLA 553
+ L PF+++ ++G + + SP L+ + S + A+ E S
Sbjct: 857 KFLLNAEK-----VPFRVDHHSGCL-LGNSPDVPLDYQKTPNFNLSIEVADHGEPMLS-T 909
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDV-----SY 608
+EV +K +F E V N IGT V + + ++ V Y
Sbjct: 910 TCFLEVELVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEY 969
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVA------LQENANLSIVTNA 662
++ G G P+ ++ G + L R R Y A ++ V +
Sbjct: 970 RIIGG--NGWPYFSIDQKGTVRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRAVLHV 1027
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ ++D ND R V + I V ENS A I ++ T+ I +G + F I
Sbjct: 1028 FIRILDRNDHRPVAKSAMY---IASVLENSPANVVIVKVEATDADDIDNDGAAPLTFKIE 1084
Query: 722 NQQDVTDDIAIAEDGTIFTQ--KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ G I T + LDREK+ + + I+ + G V + + D
Sbjct: 1085 RGDPQSFFRIDLASGYITTSGIRRLDREKQAEHELW-ISICDGGEPQLCSNVVVIVKVLD 1143
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
ENDN P F A + + + + IG K+ I A D DEG N+ Y + EG F +
Sbjct: 1144 ENDNAPTFTQAMHH-YNVRSKHIG---KLCRIF-AVDIDEGENSHLSYNV-TEGDPRFSI 1197
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE 876
DEN ++ +++ ++ Y L+L A D G S +
Sbjct: 1198 DENGNIM--TSEAIHSDES--YALTLQATDHGSPSQQ 1230
Score = 70.1 bits (164), Expect = 4e-10
Identities = 113/476 (23%), Positives = 195/476 (40%), Gaps = 46/476 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
NVEV + D N + + + S K + V+ G V+ + T
Sbjct: 1848 NVEVFVTDGNQSTSYTMKVTTTSTAENSKFKFTRQEYRASIVENSTLTPGTVILPVATTG 1907
Query: 504 ----NLTITSP---FKINPNTGTVS---VAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ TI +P F I+ TG +S +A L L VEA NP + + A
Sbjct: 1908 EKQVHFTIVNPHEAFFIHHGTGVISATGIAVDCELSPVIRLVVEAKTHEKNP---QIAKA 1964
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+V I+V + + P F+G PY VG + IGT + + +V D E + +
Sbjct: 1965 LVLIDV----QNVNDEAPKFIGTPYSITVGPSE-IGTVILEPKVIDKDEGDHATIS---- 2015
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRP--MYDFEAVALQENANLSIVTNATVHVVDVND 671
+P + G + + L + F+ +A ++ + + VVD
Sbjct: 2016 -SNDMPQYFKLVGGKVVLAKKLPAIEDQDLKFSFKLIAKDNSSVHQVEEPVVIRVVD--K 2072
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIANQQDVTDDI 730
R V + ++ +I KE++ + + + H SS+ G + + I ++ ++
Sbjct: 2073 ARPVFSQSMYTAVIS--KESTKKSTV--LVHVLARSSLQAKSKGLIGYRIIDKANLFSID 2128
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND-NPPVFEH 789
+ + + LD + Y V A + A QV I ++ ++ P F+
Sbjct: 2129 YVTGEVRLKNLNGLDAAE---YVFEVEAR-EVTLPKMASRAQVKIVVKSKSAVQKPTFDK 2184
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMFDVDENTGVVK 847
Y + E++ IG II + N + Y L G + + MF++D TG V
Sbjct: 2185 QKYSVTVPESASIG-----QRIITINSSTPDPNDILQYKLSGTNDDQPMFEIDSETGEVS 2239
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGL-SSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ LD EK YK+ ++A + SSEA+LI+MI D NDN P F + E ++V
Sbjct: 2240 -VNRHLDYEKVQKYKMLVIATSSAKQQSSEADLIVMIEDVNDNMPVFIRPEVKAEV 2294
Score = 69.7 bits (163), Expect = 6e-10
Identities = 72/271 (26%), Positives = 115/271 (42%), Gaps = 18/271 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+TV IE++NDN P + +V+++E PT + + +L R L F
Sbjct: 3000 ITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSRQYLTRIAAEDADSDDIHFRLLDDFN 3059
Query: 143 DIRAFDRD-------KPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
D KP S +++ + DG+F K ++++ V+D +
Sbjct: 3060 KTFEIDEFSGVVTVLKPLDSESVSSFNLTAIASDGNF----EDKAIIVVT-VIDKNDNAP 3114
Query: 196 EFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFL 255
F+ S K + E + E T+ Y L + + K SL++ NG L L
Sbjct: 3115 TFEKSTY-SMKVMESEAVGYELARLQAFGGDTNETIEYSLKASDHNKFVSLNAQNGVLTL 3173
Query: 256 EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI 315
+ LD + +T L V A P + A+VEI ++D NDN P+FE + Y +
Sbjct: 3174 AQPLDFET-----ISTLRLTVIAKDSGIPPLESVAQVEISVMDENDNAPKFEKEKYTGKV 3228
Query: 316 VENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
EN G VL V A D D G +Y+L+
Sbjct: 3229 KENSKVGEKVLTVKAVDADSEHFGAVSYELE 3259
Score = 65.7 bits (153), Expect = 9e-09
Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 6/170 (3%)
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNL 267
I E++ E D+ L Y +I GN FS+D G++ LD +
Sbjct: 944 IGTEVIMVEAKEMGDEQKVKAENLEYRIIGGNGWPYFSIDQ-KGTVRTTHILDREKRSAY 1002
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ +P + A V I +LD ND+ P + Y S++EN P +++
Sbjct: 1003 WITVEARDAKTDFYKDPRRRAVLHVFIRILDRNDHRPVAKSAMYIASVLENSPANVVIVK 1062
Query: 328 VMATDKDQGEN---GEFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDRE 372
V ATD D +N T++++ DP+ F ID SG++T LDRE
Sbjct: 1063 VEATDADDIDNDGAAPLTFKIERGDPQSFFRIDLASGYITTSGIRRLDRE 1112
Score = 64.5 bits (150), Expect = 2e-08
Identities = 100/468 (21%), Positives = 191/468 (40%), Gaps = 44/468 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ V + +LD NDN P F + + ++ +A VGT + A+D D +G + + L
Sbjct: 2696 AITTVTLDILDVNDNAPAF-HGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLV 2754
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTI 557
F++N ++G ++VA +P+ + + L A+D+ ++ ++++V +
Sbjct: 2755 NKD-----PHFEMNGDSGWLTVA-APLDRETQDLYQLIARATDEGGFNTDLSFTISVNDV 2808
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+ K K + + P SN I I+ D N + G EEG
Sbjct: 2809 NDSP-PKFEKDEFDVDLLLP------SNALILHF--DIKDEDLAPNNHSLLFISEGNEEG 2859
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
V F ++ + ++ ++ N+ Y + +A + T +H+ D +
Sbjct: 2860 V-FWIDSENNLLLKRPEIVE-NKKEYSLKIIAF--DGVFEAKTLVKIHLKSKEDVK-TRC 2914
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+I G+ SS+ G N F + + + +G
Sbjct: 2915 PDVEKTVILPESSKKGTVVFGE------SSLLGP---NTTFKLIEEGAENAFVMNFRNGI 2965
Query: 738 IFTQK--PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
I ++ +D EK + + + K + ++T+ IE+ NDNPP + +
Sbjct: 2966 IKVKEVGQIDYEKTQEFELIRLTIQGKDELCKE---RITVKIENLNDNPPKIKEKSVYVS 3022
Query: 796 IMENSKIGTEIKMD-NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
I EN + + I A DAD + L + + F++DE +GVV + LD
Sbjct: 3023 IEENLPTSQDSRQYLTRIAAEDADSDD---IHFRLLDDFNKTFEIDEFSGVVTVL-KPLD 3078
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
E + L+ +A D G +A +++ + D+NDN P F + + KV
Sbjct: 3079 SESVSSFNLTAIASD-GNFEDKAIIVVTVIDKNDNAPTFEKSTYSMKV 3125
Score = 63.7 bits (148), Expect = 4e-08
Identities = 56/217 (25%), Positives = 94/217 (43%), Gaps = 19/217 (8%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
LF +PE+ IG + + ++ + ++R+ +P S++S L F +
Sbjct: 2616 LFFVPEDADIGDVVGSVQQMETEID---EVRFTI-----VPGSEVSDSLLP----FSVER 2663
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G +IV SL E ++++ I A G ++ +V + + DVND+ P F + +
Sbjct: 2664 STGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTLDILDVNDNAPAFHGDYDKLTI 2723
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + A D D + + + + D FE++ +G L+V LDRET+D
Sbjct: 2724 SEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNKDPH--FEMNGDSGWLTVAAPLDRETQD 2781
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y L A D G DVND+ PKF
Sbjct: 2782 LYQLIARATDEG---GFNTDLSFTISVNDVNDSPPKF 2815
Score = 61.7 bits (143), Expect = 2e-07
Identities = 85/341 (24%), Positives = 153/341 (44%), Gaps = 43/341 (12%)
Query: 70 IGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFI----------- 118
+ AG SA ++ + I+DVN++ P F + Y++ + E G+ F
Sbjct: 688 VDAGTPVKSATRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNN 747
Query: 119 ----FLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL 174
F + G ++ P+ I K + DR++ DVHY + +DDG
Sbjct: 748 GKIKFSLGNNGAESSVISIEPK-TGIIKLLNPLDREE-----QDVHYFSIIASDDG---- 797
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEI---LFPEPIHAIDQDLGVGATL 231
+ + V L +D D D + V + RI +++ F + A D+D+G+ + L
Sbjct: 798 DPARITVTNLTITVD-DVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKL 856
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
++ L + ++ F +D +G L L D+ ++ N F L ++ + P+ +
Sbjct: 857 KFLLNA--EKVPFRVDHHSGCL-LGNSPDVPLDYQKTPN-FNLSIEVADHGEPMLSTTCF 912
Query: 292 VEIELLDL-NDNLP-EFEVDFYNISIVENLPNGFSVLQVMATD-----KDQGENGEFTYQ 344
+E+EL+D+ + +L EF+ S+ EN G V+ V A + K + EN E+
Sbjct: 913 LEVELVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEYRII 972
Query: 345 LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ FSID + TVR +LDRE S+ + V A++
Sbjct: 973 GGNGWPYFSIDQKG---TVRTTHILDREKRSAYWITVEARD 1010
Score = 60.9 bits (141), Expect = 3e-07
Identities = 102/475 (21%), Positives = 198/475 (41%), Gaps = 43/475 (9%)
Query: 434 YYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
Y D + + ++V + +LD ND+ PV S +Y S+ N+ VI KV+A D D N
Sbjct: 1016 YKDPRRRAVLHVFIRILDRNDHRPV-AKSAMYIASVLENSPANVVIVKVEATDADDIDND 1074
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERR 549
+ S F+I+ +G ++ + L+ H L++ D +
Sbjct: 1075 GAAPLTFKIERGDPQSFFRIDLASGYITTSGIRRLDREKQAEHELWISICD---GGEPQL 1131
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGS-NVGIGTSVGQIRVNDAFEQNDVSY 608
S VV ++V + P F A + + V S ++G + + +++ E + +SY
Sbjct: 1132 CSNVVVIVKVL----DENDNAPTFTQAMHHYNVRSKHIGKLCRIFAVDIDEG-ENSHLSY 1186
Query: 609 DLLHGYEEGVPFAVEERSGVITVV----DDLSRYNRPMYDFEAVALQENANLSIVTNA-T 663
++ G F+++E ++T D+ D + + Q A ++T +
Sbjct: 1187 NVTEGDPR---FSIDENGNIMTSEAIHSDESYALTLQATDHGSPSQQFAATRVVLTAVGS 1243
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKE-NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ ++ G S + + + + G +G++ T+ +G + +
Sbjct: 1244 SQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKLEATD-----ADGDDLWWNIFSG 1298
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
D D+ + G + K ++ KR R+ + + V I QV+ I
Sbjct: 1299 DSDSVFDVR-QDTGQLLLAKKVELLKRGELRLNISVTDGQDVDHTTVIIQVSRQISQR-- 1355
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----KEMFD 838
P F Y+ + E +GT+I + +KAT + GT L +Y+LF ++
Sbjct: 1356 --PAFSANRYDTLVSERVAVGTQI---HTLKATGENLGTKPL-VYSLFSIDDIAMEDKIR 1409
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
V+ ++G V + + LD E + ++V + S ++LI+ + DENDN P F
Sbjct: 1410 VEPSSGNV-IVMEPLDYEVASQIR-AVVQVQQANMKSFSKLILEVTDENDNAPYF 1462
Score = 59.3 bits (137), Expect = 8e-07
Identities = 89/426 (20%), Positives = 173/426 (40%), Gaps = 35/426 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLN-GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
EN P I+K+ A D D N G F E P S +F I+ G+
Sbjct: 1052 ENSPANVVIVKVEATDADDIDNDGAAPLTFKIERGDPQS-----------FFRIDLASGY 1100
Query: 1001 VIVA--RSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + R L E +E L IS DGG L N+ V V V D ND+ P F + +++NV
Sbjct: 1101 ITTSGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTFTQAMHHYNV 1160
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
+ L ++ A D D G+N++L+Y + ++ D F I +++ +++
Sbjct: 1161 RSKHIGK--LCRIFAVDIDEGENSHLSYNV--TEGDPRFSIDENGNIMTSEA---IHSDE 1213
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
Y LT+ A D+G + + K ++ K + + +
Sbjct: 1214 SYALTLQATDHGSPSQQFAATRVVLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQ 1273
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFANDTDFI----GNGNGLILYSLPQRKNQQNLGLP 1230
+ + +AT + + +F+ D+D + + L+L + + L L
Sbjct: 1274 VGLTVGKLEATDADGDDLWW---NIFSGDSDSVFDVRQDTGQLLLAKKVELLKRGELRLN 1330
Query: 1231 -SLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT-EHYENF 1288
S++ + T + ++S +P F + Y+ + E V ++ +L T E+
Sbjct: 1331 ISVTDGQDVDHTTVIIQVSRQISQRPAFSANRYDTLVSERVAVGTQIHTLKATGENLGTK 1390
Query: 1289 KMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMI 1348
+ Y + + +D + ++P +G + ++ D EV +V+ + Q + +I
Sbjct: 1391 PLVYSLFSIDDIAMEDKIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQ-QANMKSFSKLI 1449
Query: 1349 YPVAED 1354
V ++
Sbjct: 1450 LEVTDE 1455
Score = 59.3 bits (137), Expect = 8e-07
Identities = 54/190 (28%), Positives = 88/190 (46%), Gaps = 9/190 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN +G ++ + A+D DS G + YE + S S V F IN +G
Sbjct: 3228 VKENSKVGEKVLTVKAVDADSEHFGAVSYELEL-IADKASDDSLPTTSVTPPFSINA-NG 3285
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
V++ + + E ++ L + A DGG L + + V D ND+ PVF V+
Sbjct: 3286 DVLINQPIDYEKTKKYNLKLIAKDGGRPPLVSEALLDIHVGDENDNAPVFDDCNMTAVVQ 3345
Query: 1056 EAQYTRRVLGKVDATDADFGQN-ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + + K +D D N A T IQ D F+++ +L+ +L+ +D
Sbjct: 3346 EGESIGHKVLKFSISDLDGPTNGAPFTVEIQ-GDGAKSFKVNDKLELLTAK-KLEHRNKD 3403
Query: 1115 KYILTVVARD 1124
KY+LTV+A+D
Sbjct: 3404 KYLLTVIAKD 3413
Score = 58.0 bits (134), Expect = 2e-06
Identities = 64/242 (26%), Positives = 110/242 (45%), Gaps = 22/242 (9%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
K F +D +G + + K LD ++ ++F L AS N K A + + ++D ND
Sbjct: 3060 KTFEIDEFSGVVTVLKPLDSES-----VSSFNLTAIASDGNFEDK---AIIVVTVIDKND 3111
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL 361
N P FE Y++ ++E+ G+ + ++ A D E E++ + D S++ ++G L
Sbjct: 3112 NAPTFEKSTYSMKVMESEAVGYELARLQAFGGDTNETIEYSLKASDHNKFVSLNAQNGVL 3171
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTTYV 420
T+ LD E S+LR+ V AK++ + + A + NAP EK Y
Sbjct: 3172 TLAQP--LDFETISTLRLTVIAKDSGIPPLESVAQVEISV----MDENDNAPKFEKEKYT 3225
Query: 421 FP----DKVGTKTENIEYYDEQLMSF--VNVEVTLL-DANDNNPVFVPSNLYEFSMKSNA 473
KVG K ++ D F V+ E+ L+ D ++ + S FS+ +N
Sbjct: 3226 GKVKENSKVGEKVLTVKAVDADSEHFGAVSYELELIADKASDDSLPTTSVTPPFSINANG 3285
Query: 474 KV 475
V
Sbjct: 3286 DV 3287
Score = 57.6 bits (133), Expect = 2e-06
Identities = 33/104 (31%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ A + + + ++D+ND P F + FY+ SI E G +VL V ATD+D+ + E++
Sbjct: 2487 RRAFSTLTLSVIDINDKPPFFVLPFYSTSIPETAKEGDTVLMVSATDEDENDTIEYSLLD 2546
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NP 388
FS+ PR G +TV + L+ +A +L + + A ++ NP
Sbjct: 2547 GGESQFFSVHPRQGTITVSKK--LEHKAGVTLSLTIKATDSANP 2588
Score = 57.6 bits (133), Expect = 2e-06
Identities = 71/295 (24%), Positives = 119/295 (40%), Gaps = 35/295 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE G T++ ++A D D N I Y D E ++F ++ R G
Sbjct: 2516 IPETAKEGDTVLMVSATDEDE--NDTIEYSL------------LDGGE-SQFFSVHPRQG 2560
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V++ L ++ L I A D N + +V + V + P F + Y F V
Sbjct: 2561 TITVSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVASESVRVPRFSNSHYLFFVP 2620
Query: 1056 EAQYTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E V+G V + + + + + SD+ LPF + TG + V LDRE
Sbjct: 2621 EDADIGDVVGSVQQMETEIDEVRFTIVPGSEVSDSLLPFSVERSTGKIIVKSSLDRERRK 2680
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
++ +T+ A G DVNDN+P F H + D+L+
Sbjct: 2681 QWKMTIRADAAGGVHAITTVTLDIL---DVNDNAPAF----------HGDYDKLTISEDA 2727
Query: 1175 SV-MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG-NGLILYSLPQRKNQQNL 1227
+V + ++ A +++P G + D F NG +G + + P + Q+L
Sbjct: 2728 TVGTSVTIFSAMDRDDSPSGRIRFSLVNKDPHFEMNGDSGWLTVAAPLDRETQDL 2782
Score = 55.6 bits (128), Expect = 1e-05
Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 10/190 (5%)
Query: 202 MASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDL 261
M G + P + A D+D G + Y ++S D ++F++D +G++ K D
Sbjct: 1678 MEPGSSVLSNRHLPLVLLASDEDSGSNGLVGYRMLSKADEEMFTVDQYSGAVRTNKAFDF 1737
Query: 262 DAEHNLQANTFVLQVQASQLNNPLKTA--QARVEIELLDLNDNLPEFEVDFYNISIVENL 319
+ ++ ++F VQA + P + + A V + + D ND P+F ++ ++ L
Sbjct: 1738 E---KIKEHSFY--VQAFDMGQPPRQSLMPALVVVTISDENDETPKFASQ--SLDVIMLL 1790
Query: 320 PNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
P + D G Y + D FS+D ++G ++V++ E +
Sbjct: 1791 PTASQAVVGGQMSDDADSIGTLRYYIKDSSSPFSVDSKTGIVSVKDFKAFTNE-KKHYNV 1849
Query: 380 KVYAKETNPS 389
+V+ + N S
Sbjct: 1850 EVFVTDGNQS 1859
Score = 55.2 bits (127), Expect = 1e-05
Identities = 79/276 (28%), Positives = 117/276 (42%), Gaps = 30/276 (10%)
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVK-PKNKFALDVDQLGPLFLIPENIPIGTT 949
P FN E V H E L+ T + V P A++ D + + EN IGT
Sbjct: 891 PNFNLSIE---VADHGEPMLSTTCFLEVELVDVPHKHLAIEFDDVAKEASVYENSEIGTE 947
Query: 950 IIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
+I + A ++ G +++ E N E I + + YF I+++ G V L
Sbjct: 948 VIMVEAKEM--GDEQKVKAE-NLEYRI----IGGNGWP---YFSIDQK-GTVRTTHILDR 996
Query: 1010 E--SEFRLNISALDGGN--LND---NISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYT 1060
E S + + + A D D + VF++ D NDH PV K Y +V E
Sbjct: 997 EKRSAYWITVEARDAKTDFYKDPRRRAVLHVFIRILDRNDHRPVAKSAMYIASVLENSPA 1056
Query: 1061 RRVLGKVDATDADFGQN---ANLTYFIQPSDTDLPFEISPLTGVLSVNG--ELDRETEDK 1115
V+ KV+ATDAD N A LT+ I+ D F I +G ++ +G LDRE + +
Sbjct: 1057 NVVIVKVEATDADDIDNDGAAPLTFKIERGDPQSFFRIDLASGYITTSGIRRLDREKQAE 1116
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ L + D G D NDN+P F
Sbjct: 1117 HELWISICDGG-EPQLCSNVVVIVKVLDENDNAPTF 1151
Score = 55.2 bits (127), Expect = 1e-05
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V +++LD+NDN P F D+ ++I E+ G SV A D+D +G + L +
Sbjct: 2700 VTLDILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNKDPH 2759
Query: 352 FSIDPRSGWLTVRNQTVLDRE 372
F ++ SGWLTV LDRE
Sbjct: 2760 FEMNGDSGWLTV--AAPLDRE 2778
Score = 54.0 bits (124), Expect = 3e-05
Identities = 65/229 (28%), Positives = 98/229 (42%), Gaps = 23/229 (10%)
Query: 992 FVINERHGHVIVARSLPPES---EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKT 1048
F I+ + G + V+ L +F++ +S D V V + D N+H PV+
Sbjct: 431 FTISSKSGVLRVSSKLSISERVYKFKVAVSLHGIQGKKDERDVYVEIVDSNNHSPVWSAK 490
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
W VL KVDATD D G N + Y I ++++PFEI+ TG +++ E+
Sbjct: 491 WMRQAPIPLGKPGDVLLKVDATDQDEGDNGRVVYKI---NSEIPFEINANTGEITLI-EV 546
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN-DNSPKFYAFDELLEWKHPEADE 1167
++ + +++TV A D G PK E E KH
Sbjct: 547 PTKS-NNWMVTVWAIDLGLPLSRMSALNLMFYKNGTKVPAKPKPVIIQE-SENKHSPV-- 602
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY 1216
F S + + E+APIGT VAK+ ++D D NGLI Y
Sbjct: 603 -----FSSFPEV----VEVTEDAPIGTVVAKLQSSDED--AGYNGLIRY 640
Score = 54.0 bits (124), Expect = 3e-05
Identities = 54/242 (22%), Positives = 104/242 (42%), Gaps = 13/242 (5%)
Query: 220 AIDQDLGVGATLRYEL-ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D G +++ L +G + + S++ G + L LD + + + + A
Sbjct: 739 ANDFDGGNNGKIKFSLGNNGAESSVISIEPKTGIIKLLNPLDREEQ-----DVHYFSIIA 793
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S +P + + I + D+NDN P I E+LP+G V + A D+D G N
Sbjct: 794 SDDGDPARITVTNLTITVDDVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLN 853
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-LDREAHSSLRMKVYAKETNPSVVGT--FA 395
+ + L+ K F +D SG L + V LD + + + + + ++ T F
Sbjct: 854 SKLKFLLNAEKVPFRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFL 913
Query: 396 DSQRI-AKWRRQPLETNAPLEKTTYVFPDKVGTK---TENIEYYDEQLMSFVNVEVTLLD 451
+ + + + +E + ++ + ++GT+ E E DEQ + N+E ++
Sbjct: 914 EVELVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEYRIIG 973
Query: 452 AN 453
N
Sbjct: 974 GN 975
Score = 53.6 bits (123), Expect = 4e-05
Identities = 50/187 (26%), Positives = 86/187 (45%), Gaps = 20/187 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ +GT++ +A+D D +G+IR+ S ++ D +F +N G
Sbjct: 2723 ISEDATVGTSVTIFSAMDRDDSPSGRIRF----------SLVNKDP-----HFEMNGDSG 2767
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ VA L E++ ++L A D G N ++S + V DVND P F+K F+V+
Sbjct: 2768 WLTVAAPLDRETQDLYQLIARATDEGGFNTDLSFTISVNDVNDSPPKFEKD--EFDVDLL 2825
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ ++ D D D N + FI + + F I +L E+ E + +Y
Sbjct: 2826 LPSNALILHFDIKDEDLAPNNHSLLFISEGNEEGVFWIDSENNLLLKRPEI-VENKKEYS 2884
Query: 1118 LTVVARD 1124
L ++A D
Sbjct: 2885 LKIIAFD 2891
Score = 53.6 bits (123), Expect = 4e-05
Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 16/185 (8%)
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKD 1037
S A + ++ +N ++G + +A+ L E S RL + A D G L V + V D
Sbjct: 3152 SLKASDHNKFVSLNAQNGVLTLAQPLDFETISTLRLTVIAKDSGIPPLESVAQVEISVMD 3211
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-----PSDTDLP 1092
ND+ P F+K Y V+E + V A DAD ++Y ++ SD LP
Sbjct: 3212 ENDNAPKFEKEKYTGKVKENSKVGEKVLTVKAVDADSEHFGAVSYELELIADKASDDSLP 3271
Query: 1093 -FEISP-----LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
++P G + +N +D E KY L ++A+D G D ND
Sbjct: 3272 TTSVTPPFSINANGDVLINQPIDYEKTKKYNLKLIAKDGG-RPPLVSEALLDIHVGDEND 3330
Query: 1147 NSPKF 1151
N+P F
Sbjct: 3331 NAPVF 3335
Score = 52.4 bits (120), Expect = 9e-05
Identities = 77/315 (24%), Positives = 129/315 (40%), Gaps = 26/315 (8%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPSLT-IPLTV 134
LS T+ + DVND+ P F + V D L P+ F I AP SL I
Sbjct: 2799 LSFTISVNDVNDSPPKFEKDEFDV--DLLLPSNALILHFDIKDEDLAPNNHSLLFISEGN 2856
Query: 135 PRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
G+ +P + YS+ DG F ++ K L ++ + D
Sbjct: 2857 EEGVFWIDSENNLLLKRPEIVENKKEYSLKIIAFDGVFEAKTLVKIHLKSKEDVKTRCPD 2916
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF 254
E +++ S K+ ++F E LG T ++LI F ++ NG +
Sbjct: 2917 VEKTVILPESSKK--GTVVFGE-----SSLLGPNTT--FKLIEEGAENAFVMNFRNGIIK 2967
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS 314
+++ +D E + L +Q + + R+ +++ +LNDN P+ + +S
Sbjct: 2968 VKEVGQIDYEKTQEFELIRLTIQGKD-----ELCKERITVKIENLNDNPPKIKEKSVYVS 3022
Query: 315 IVENLPNGFSVLQVMA-TDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
I ENLP Q + + ++ + ++ LDD F ID SG +TV LD E
Sbjct: 3023 IEENLPTSQDSRQYLTRIAAEDADSDDIHFRLLDDFNKTFEIDEFSGVVTVLKP--LDSE 3080
Query: 373 AHSSLRMKVYAKETN 387
+ SS + A + N
Sbjct: 3081 SVSSFNLTAIASDGN 3095
Score = 50.4 bits (115), Expect = 4e-04
Identities = 95/456 (20%), Positives = 184/456 (40%), Gaps = 46/456 (10%)
Query: 949 TIIKLNALDLDSGLNGQI---RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
TI+ +AL L + G I RY Y S S D+ V I+++ G + V+R
Sbjct: 2412 TIVNKSAL-LTVAVKGGIPPLRYSLGPAAYSNSSS-SKDSWPV----AIDKKTGRIHVSR 2465
Query: 1006 SLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV 1063
L ++ +++ + D ++ + V D+ND P F +Y+ ++ E
Sbjct: 2466 VLNYHNDKLYQIPLVVEDVTRRRAFSTLTLSVIDINDKPPFFVLPFYSTSIPETAKEGDT 2525
Query: 1064 LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
+ V ATD D +N + Y + F + P G ++V+ +L+ + LT+ A
Sbjct: 2526 VLMVSATDED--ENDTIEYSLLDGGESQFFSVHPRQGTITVSKKLEHKAGVTLSLTIKAT 2583
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D+ + + P+F + L + +AD SV +
Sbjct: 2584 DSANPPHHATTTVEINVASE-SVRVPRF-SNSHYLFFVPEDAD--IGDVVGSVQQMETEI 2639
Query: 1184 ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP-QRKNQQNLGLPSLSSTAILMVTV 1242
+ G+ V+ + G ++ SL +R+ Q + + + ++ + +T
Sbjct: 2640 DEVRFTIVPGSEVSDSLLPFSVERSTGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITT 2699
Query: 1243 ADVPDEVEMSDK-PVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYYILNEND 1299
+ D ++++D P F Y +L I E+ V V + S + + ++R+ ++N++
Sbjct: 2700 VTL-DILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNKDP 2758
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
F ++ +G L + DRE +D Y++I RA EG
Sbjct: 2759 -----HFEMNGDSGWLTVAAPLDRETQDLYQLIARATD-------------------EGG 2794
Query: 1360 TKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTA 1395
D+ + + DVND+ PKF + +P+ A
Sbjct: 2795 FNTDLSFTISVNDVNDSPPKFEKDEFDVDLLLPSNA 2830
Score = 49.2 bits (112), Expect = 9e-04
Identities = 52/203 (25%), Positives = 79/203 (38%), Gaps = 9/203 (4%)
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPLTGV 1101
P F K Y+ V E+ + + ++++ D N L Y + ++ D P FEI TG
Sbjct: 2180 PTFDKQKYSVTVPESASIGQRIITINSSTPD--PNDILQYKLSGTNDDQPMFEIDSETGE 2237
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+SVN LD E KY + V+A DVNDN P F E K
Sbjct: 2238 VSVNRHLDYEKVQKYKMLVIA--TSSAKQQSSEADLIVMIEDVNDNMPVFIR----PEVK 2291
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR 1221
+D + F ++M T + P + K+ D SL +R
Sbjct: 2292 AEVSDAAISGQFITIMSATDMDTTSSLDDPNQKLLYKIVDGDETLFNISPSTGEVSLARR 2351
Query: 1222 KNQQNLGLPSLSSTAILMVTVAD 1244
Q++L S ++ V+V D
Sbjct: 2352 IEQEDLTSESEDPKKVVNVSVTD 2374
Score = 48.0 bits (109), Expect = 0.002
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 21/232 (9%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
E A D D A L +++ G+ + F +D +G + LD E + ++
Sbjct: 1064 EATDADDIDNDGAAPLTFKIERGDPQSFFRIDLASGYITTSGIRRLDREKQAEHELWISI 1123
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ P + V +++LD NDN P F ++ + V + G + ++ A D D+
Sbjct: 1124 CDGGE---PQLCSNVVVIVKVLDENDNAPTFTQAMHHYN-VRSKHIG-KLCRIFAVDIDE 1178
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVR-------NQTVLDREAHSSLRMKVYAKETNP 388
GEN +Y + + FSID +T L H S + A
Sbjct: 1179 GENSHLSYNVTEGDPRFSIDENGNIMTSEAIHSDESYALTLQATDHGSPSQQFAATRVVL 1238
Query: 389 SVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFP----DKVGTKTENIEYYD 436
+ VG+ SQ+ K + P + +K+ YV P D+VG +E D
Sbjct: 1239 TAVGS---SQKTKKSKNSPPVISG--KKSDYVIPISDADQVGLTVGKLEATD 1285
Score = 46.4 bits (105), Expect = 0.006
Identities = 46/172 (26%), Positives = 78/172 (45%), Gaps = 18/172 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D T+ Y L+ G + + FS+ G++ + K+L EH T L ++
Sbjct: 2529 VSATDED--ENDTIEYSLLDGGESQFFSVHPRQGTITVSKKL----EHKAGV-TLSLTIK 2581
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV--LQVMATDKDQ 335
A+ NP A VEI + + +P F Y + E+ G V +Q M T+ D+
Sbjct: 2582 ATDSANPPHHATTTVEINVASESVRVPRFSNSHYLFFVPEDADIGDVVGSVQQMETEIDE 2641
Query: 336 GENGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
FT ++ D FS++ +G + V++ LDRE +M + A
Sbjct: 2642 ---VRFTIVPGSEVSDSLLPFSVERSTGKIIVKSS--LDRERRKQWKMTIRA 2688
Score = 45.6 bits (103), Expect = 0.011
Identities = 58/217 (26%), Positives = 94/217 (43%), Gaps = 26/217 (11%)
Query: 906 RETKLNGTAGFTIIEVKPKNKFALD---VDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
RE L A +++ K+K A+ D+ +PE+ IG II +N+ D
Sbjct: 2154 REVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRIITINSSTPDP-- 2211
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISAL 1020
N ++Y KLS + + F I+ G V V R L E ++++ + A
Sbjct: 2212 NDILQY-----------KLSGTN-DDQPMFEIDSETGEVSVNRHLDYEKVQKYKMLVIAT 2259
Query: 1021 DGGNLNDN-ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF----- 1074
+ + V ++DVND+ PVF + V +A + + + + ATD D
Sbjct: 2260 SSAKQQSSEADLIVMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSLD 2319
Query: 1075 GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
N L Y I D L F ISP TG +S+ +++E
Sbjct: 2320 DPNQKLLYKIVDGDETL-FNISPSTGEVSLARRIEQE 2355
Score = 44.8 bits (101), Expect = 0.018
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+E G + + LD EK Y+M VIA + S + + IED NDN PVF
Sbjct: 2233 SETGEVSVNRHLDYEKVQKYKMLVIATSSAKQQSSEA--DLIVMIEDVNDNMPVFIRPEV 2290
Query: 793 EGFIMENSKIGTEIKMDNIIKATDAD-----EGTNALFMYTLFGEGKEMFDVDENTGVV- 846
+ + + + G I I+ ATD D + N +Y + + +F++ +TG V
Sbjct: 2291 KAEVSDAAISGQFI---TIMSATDMDTTSSLDDPNQKLLYKIVDGDETLFNISPSTGEVS 2347
Query: 847 ---KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI--GDENDNKPEFNQ 895
+ + L E + K+ V+ G ++ A+L++ I + P+F Q
Sbjct: 2348 LARRIEQEDLTSESEDPKKVVNVSVTDGMFTAYAKLVVGILRSGKMQPPPKFEQ 2401
Score = 44.4 bits (100), Expect = 0.024
Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 236 ISGNDRKLFSLDS--VNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNNPLKTAQ--A 290
I+G LF + V +FL D N + F + V+A+ L + A
Sbjct: 78 IAGEKSSLFKAHARQVGDFVFLRIRYKGDNPLNRELKDFYDILVKATCKRRDLSNLETTA 137
Query: 291 RVEIELLDLNDNLPEFEVDFYNI-SIVENLPNGFS-VLQVMATDKDQGENGEFTYQLDDP 348
R+ + ++D ND P F VD +++++ FS VL+V A+D D G N + L +
Sbjct: 138 RIHLRVIDKNDASPLFLVDEQGYEAVIDDDTEPFSTVLRVEASDADIGINSAIYFSLVNR 197
Query: 349 KGAFSIDPRSGWL-TVRN 365
F ++P SGW+ T+R+
Sbjct: 198 SHDFLVEPVSGWIRTLRH 215
Score = 44.0 bits (99), Expect = 0.032
Identities = 44/180 (24%), Positives = 74/180 (41%), Gaps = 15/180 (8%)
Query: 721 ANQQDVTDDIAIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+N D +A D G I + L+ +Y++ ++ E V +T+ +
Sbjct: 2441 SNSSSSKDSWPVAIDKKTGRIHVSRVLNYHNDKLYQIPLVVE---DVTRRRAFSTLTLSV 2497
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EM 836
D ND PP F Y I E +K G + M + ATD DE N Y+L G+ +
Sbjct: 2498 IDINDKPPFFVLPFYSTSIPETAKEGDTVLM---VSATDEDE--NDTIEYSLLDGGESQF 2552
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFN 894
F V G + + L+ + + L++ A D+ A + I + E+ P F+
Sbjct: 2553 FSVHPRQGTIT-VSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVASESVRVPRFS 2611
Score = 43.2 bits (97), Expect = 0.056
Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D + Y ++SGN+ LF +DS +G + L + +D + +H + +L+++
Sbjct: 1484 VTAFDRDQDDNGIITYSIVSGNEESLFKIDSHSGEVRLARLIDPEMQHVVS----ILRIR 1539
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS + + I+ L +F+ Y S+ ++ G VL +
Sbjct: 1540 ASDSATISLKDELTLHIKSSKLTSENAKFDRKVYQTSLHDSTRPGTPVLVLNVL-----H 1594
Query: 338 NGEFTYQLDDPKGAFSIDPRSG 359
+G T++L+ F + SG
Sbjct: 1595 HGAITFKLEPNCTFFDVHTLSG 1616
Score = 39.1 bits (87), Expect = 0.92
Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSID 355
N + P F + + E+ P G V ++ ++D+D G NG Y + D G+ S+D
Sbjct: 597 NKHSPVFSSFPEVVEVTEDAPIGTVVAKLQSSDEDAGYNGLIRYVIQDISGSSHEILSVD 656
Query: 356 PRSGWLTVRNQ-TVLDREAHSSLRMKV 381
+SG +TV + T+L +E + ++V
Sbjct: 657 EQSGEITVASDLTLLMKEKQKVVEIQV 683
Score = 38.7 bits (86), Expect = 1.2
Identities = 30/127 (23%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
S N F++ S +G L + +L ++ + +V S K + V +E+
Sbjct: 424 SSNISLPFTISSKSGVLRVSSKL------SISERVYKFKVAVSLHGIQGKKDERDVYVEI 477
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
+D N++ P + + + + G +L+V ATD+D+G+NG Y+++ + F I+
Sbjct: 478 VDSNNHSPVWSAKWMRQAPIPLGKPGDVLLKVDATDQDEGDNGRVVYKINS-EIPFEINA 536
Query: 357 RSGWLTV 363
+G +T+
Sbjct: 537 NTGEITL 543
Score = 38.7 bits (86), Expect = 1.2
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 11/172 (6%)
Query: 991 YFVINERHGHVIVARSLPPESEFR-LNISA--LDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
+F ++ G V +A+ + E + + L +A ++G D + + N H PVF+K
Sbjct: 1608 FFDVHTLSGAVHLAKWITKEKQLKTLECTAYVVNGDGQQDTAKIVAKIIRTNQHSPVFRK 1667
Query: 1048 TWYNFNVEE------AQYTRRVLGKV-DATDADFGQNANLTYFIQPSDTDLPFEISPLTG 1100
Y V E + + R L V A+D D G N + Y + + F + +G
Sbjct: 1668 QVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSGSNGLVGYRMLSKADEEMFTVDQYSG 1727
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGX-XXXXXXXXXXXXXXXDVNDNSPKF 1151
+ N D E ++ V A D G D ND +PKF
Sbjct: 1728 AVRTNKAFDFEKIKEHSFYVQAFDMGQPPRQSLMPALVVVTISDENDETPKF 1779
Score = 38.3 bits (85), Expect = 1.6
Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 13/136 (9%)
Query: 231 LRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
L+Y+L ND + +F +DS G + + + LD + + +L + S A
Sbjct: 2215 LQYKLSGTNDDQPMFEIDSETGEVSVNRHLDYEKVQKYK----MLVIATSSAKQQSSEAD 2270
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-----QGENGEFTYQ 344
V IE D+NDN+P F + + +G + + ATD D N + Y+
Sbjct: 2271 LIVMIE--DVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSLDDPNQKLLYK 2328
Query: 345 L-DDPKGAFSIDPRSG 359
+ D + F+I P +G
Sbjct: 2329 IVDGDETLFNISPSTG 2344
Score = 37.9 bits (84), Expect = 2.1
Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 11/145 (7%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
FS+++ NG + + + +D + + + L++ A P ++A ++I + D NDN
Sbjct: 3279 FSINA-NGDVLINQPIDYE-----KTKKYNLKLIAKDGGRPPLVSEALLDIHVGDENDNA 3332
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLD-DPKGAFSIDPRSGWL 361
P F+ + E G VL+ +D D NG FT ++ D +F ++ + L
Sbjct: 3333 PVFDDCNMTAVVQEGESIGHKVLKFSISDLDGPTNGAPFTVEIQGDGAKSFKVNDKLELL 3392
Query: 362 TVRNQTVLDREAHSSLRMKVYAKET 386
T + L+ + V AK+T
Sbjct: 3393 TAKK---LEHRNKDKYLLTVIAKDT 3414
Score = 37.5 bits (83), Expect = 2.8
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 4/150 (2%)
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN-ISALDGGNLNDNISVRVFVKD 1037
S S D + ++ + G+VIV L E ++ + + N+ + + V D
Sbjct: 1395 SLFSIDDIAMEDKIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQQANMKSFSKLILEVTD 1454
Query: 1038 VNDHFPVF-KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS 1096
ND+ P F + T + F V+E VL V A D D N +TY I + + F+I
Sbjct: 1455 ENDNAPYFVEHTAWAF-VDENDSVDDVLATVTAFDRDQDDNGIITYSIVSGNEESLFKID 1513
Query: 1097 PLTGVLSVNGELDRETEDKY-ILTVVARDN 1125
+G + + +D E + IL + A D+
Sbjct: 1514 SHSGEVRLARLIDPEMQHVVSILRIRASDS 1543
Score = 37.5 bits (83), Expect = 2.8
Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 27/207 (13%)
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
N NGL + + LP ++S A + + V KP F + Y + + E
Sbjct: 2138 NLNGLDAAEYVFEVEAREVTLPKMASRAQVKIVVKSK----SAVQKPTFDKQKYSVTVPE 2193
Query: 1269 NVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDT 1328
+ + ++++N + N ++Y + ND + F ID G + + R D E
Sbjct: 2194 SASIGQRIITINSSTPDPNDILQYKLSGTNDD--QPMFEIDSETGEVSVNRHLDYEKVQK 2251
Query: 1329 YEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
Y+++V A + + ++V I+DVNDN P F RP V
Sbjct: 2252 YKMLVIATSSAKQQSS------------------EADLIVMIEDVNDNMPVFI---RPEV 2290
Query: 1389 TAIPTTAPFGYQVMQLKGAIGHHPTAS 1415
A + A Q + + A T+S
Sbjct: 2291 KAEVSDAAISGQFITIMSATDMDTTSS 2317
Score = 36.7 bits (81), Expect = 4.9
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 11/108 (10%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ------ 327
L+ A +N + A++ +++ N + P F Y ++ EN+ G SVL
Sbjct: 1633 LECTAYVVNGDGQQDTAKIVAKIIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPL 1692
Query: 328 -VMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
++A+D+D G NG Y++ + F++D SG VR D E
Sbjct: 1693 VLLASDEDSGSNGLVGYRMLSKADEEMFTVDQYSG--AVRTNKAFDFE 1738
Score = 36.7 bits (81), Expect = 4.9
Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D+D +R+ L++ + F ++ +G L + LD + + Q
Sbjct: 2738 AMDRDDSPSGRIRFSLVNKDPH--FEMNGDSGWLTVAAPLDRETQDLYQL--IARATDEG 2793
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
N L I + D+ND+ P+FE D +++ ++ LP+ +L D+D N
Sbjct: 2794 GFNTDLSFT-----ISVNDVNDSPPKFEKDEFDVDLL--LPSNALILHFDIKDEDLAPNN 2846
Query: 340 EFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREAHS 375
+ + +G F ID + L R + V +++ +S
Sbjct: 2847 HSLLFISEGNEEGVFWIDSENNLLLKRPEIVENKKEYS 2884
Score = 35.9 bits (79), Expect = 8.6
Identities = 16/40 (40%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAAL 1479
+A+D+DIGIN+ I + ++N ++ F ++PVSG +R + L
Sbjct: 178 EASDADIGINSAIYFSLVN-RSHDFLVEPVSGWIRTLRHL 216
>UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio
rerio|Rep: Paraxial protocadherin - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 950
Score = 105 bits (251), Expect = 1e-20
Identities = 121/521 (23%), Positives = 223/521 (42%), Gaps = 42/521 (8%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ + ++ ++VE+ + D ND++P F + + + +A + + AVD D
Sbjct: 95 TFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETH-LDISEDAPLNSRFPLDVAVDHD 153
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANP 545
+G N + Y + S+ + + + V + E + + V A+D A
Sbjct: 154 VGDNYIQSYHISHNSHFVVEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAPQ 213
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
+L + ++ + P F + + + + IG+ V ++ D
Sbjct: 214 KSGSTTLYIRVLDFNDNS-------PTFEHSSLKVELSEDSPIGSRVLKVHAFDP--DAG 264
Query: 606 VSYDLLHGYEEGVP------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSI 658
++ ++++G+ EG P F ++ SG +T+ D + + Y+ A AN +S
Sbjct: 265 INGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGANSVSS 324
Query: 659 VTNATVHVVDVNDERG-VLLKGAHSPI--IFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
A V ++DVND +++K S + + E +A + + T+ NG
Sbjct: 325 TCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFVALISTSDKDSGPNGY-- 382
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
VR + + A ++ I T LDRE Y +TVI+E + G + TI
Sbjct: 383 VRTSLEGHEHFKLQQAYSDTFMIITTTTLDRESISEYNLTVISE-DLGTPPFKTVKHYTI 441
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----- 830
I DENDNPP+F + Y+ ++EN+ G+ + + A D D G N Y+L
Sbjct: 442 RITDENDNPPLFSKSIYDVSVIENNIPGSYM---TTVVARDLDAGKNGKVSYSLVESKAP 498
Query: 831 -GEGKEMF-DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
G F VD ++G + + S D E + S+ A D G LSS + + + D+
Sbjct: 499 DGSSISTFVSVDPHSGSL-YTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDD 557
Query: 887 NDNKPEFN-QIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
NDN P F + N+ I +N G+ ++V K++
Sbjct: 558 NDNFPYFTYPVLRNNSAEI--PIPMNANTGYLALKVAAKDE 596
Score = 76.6 bits (180), Expect = 5e-12
Identities = 94/418 (22%), Positives = 179/418 (42%), Gaps = 32/418 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ +LD NDN+P F S+L + + ++ +G+ + KV A DPD G NG ++Y S
Sbjct: 222 IRVLDFNDNSPTFEHSSL-KVELSEDSPIGSRVLKVHAFDPDAGINGEIVYGFVEGSPSE 280
Query: 507 ITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
+T F+I+ +G V++ + E + + L ++ASD AN V I+V
Sbjct: 281 VTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVN---- 336
Query: 565 GNKPDI---PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPF 620
N P+I P + ++ + V I +D N L G+E
Sbjct: 337 DNAPEIIIKPMTSTSDGVAFITEAAAEESFVALISTSDKDSGPNGYVRTSLEGHEHFKLQ 396
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKG 679
+ +I L R + Y+ ++ V + T+ + D ND + K
Sbjct: 397 QAYSDTFMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKS 456
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD---VTDDIAI-AED 735
+ + ++ N G+ + + ++ + NG + + + D ++ +++
Sbjct: 457 IYDVSV--IENNIPGSYMTTVVARDLDA-GKNGKVSYSLVESKAPDGSSISTFVSVDPHS 513
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G+++T + D E + +V A +KG S + + + + D+NDN P F TY
Sbjct: 514 GSLYTLRSFDFETLKDVQFSVKAT-DKGFPSLSSTTLIQVRVVDDNDNFPYF---TYP-- 567
Query: 796 IMENSKIGTEIKMD-NI------IKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
++ N+ I M+ N + A D D G N+ Y + + ++F +D+NTG +
Sbjct: 568 VLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSELNYHILEDEAKLFSIDKNTGEI 625
Score = 76.2 bits (179), Expect = 7e-12
Identities = 107/428 (25%), Positives = 181/428 (42%), Gaps = 42/428 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ PIG+ ++K++A D D+G+NG+I Y F V PS EV R F I+ G
Sbjct: 243 LSEDSPIGSRVLKVHAFDPDAGINGEIVYGF---VEGSPS-------EVTRVFQIDLISG 292
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFP-VFKKTWYNFN- 1053
V + + E++ + L+I A D G + + + R V DVND+ P + K + +
Sbjct: 293 EVTLKDIVDYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSD 352
Query: 1054 ----VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ EA + + +D D G N + ++ + + T ++ LD
Sbjct: 353 GVAFITEAAAEESFVALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTTTLD 412
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFD-ELLEWKHPEA- 1165
RE+ +Y LTV++ D G D NDN P F +D ++E P +
Sbjct: 413 RESISEYNLTVISEDLG-TPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSY 471
Query: 1166 -DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
+ + ++ V + +E AP G++++ F + G+ L + K+
Sbjct: 472 MTTVVARDLDAGKNGKVSYSLVESKAPDGSSIS-TFVSVDPHSGSLYTLRSFDFETLKDV 530
Query: 1225 Q------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
Q + G PSLSST ++ V V D D PV + E+ I N N +
Sbjct: 531 QFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANTGYLALK 590
Query: 1279 LNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR---SPDREVKDTYEVIV 1333
+ + N ++ Y+IL D + F ID G + L R + E+ Y +V
Sbjct: 591 VAAKDEDSGINSELNYHILE----DEAKLFSIDKNTGEIILKRKLTASCGEILQIYVSVV 646
Query: 1334 RAERQKYS 1341
R+ S
Sbjct: 647 DGAREPLS 654
Score = 64.9 bits (151), Expect = 2e-08
Identities = 47/163 (28%), Positives = 83/163 (50%), Gaps = 10/163 (6%)
Query: 996 ERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYN 1051
E+ +++ +SL E+E + + ++A DGG + S ++++ D ND+ P F+ +
Sbjct: 181 EKSAELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLK 240
Query: 1052 FNV-EEAQYTRRVLGKVDATDADFGQNANLTY-FIQ--PSDTDLPFEISPLTGVLSVNGE 1107
+ E++ RVL KV A D D G N + Y F++ PS+ F+I ++G +++
Sbjct: 241 VELSEDSPIGSRVL-KVHAFDPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDI 299
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+D ET+ Y L + A D G DVNDN+P+
Sbjct: 300 VDYETKKSYELHIQASDLG-ANSVSSTCRAIVDIIDVNDNAPE 341
Score = 64.1 bits (149), Expect = 3e-08
Identities = 54/190 (28%), Positives = 86/190 (45%), Gaps = 19/190 (10%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS-----VNGSLFLEKELDLDAEHNLQ 268
FP + A+D D+G Y IS N + + + + L L K LD + E
Sbjct: 144 FPLDV-AVDHDVGDNYIQSYH-ISHNSHFVVEVSTREDGEKSAELVLIKSLDRETE---- 197
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQV 328
+ + ++V A+ P K+ + I +LD NDN P FE + + E+ P G VL+V
Sbjct: 198 -DFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSPIGSRVLKV 256
Query: 329 MATDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
A D D G NGE Y + F ID SG +T+++ ++D E S + + A
Sbjct: 257 HAFDPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKD--IVDYETKKSYELHIQA 314
Query: 384 KETNPSVVGT 393
+ + V +
Sbjct: 315 SDLGANSVSS 324
Score = 60.5 bits (140), Expect = 3e-07
Identities = 58/239 (24%), Positives = 105/239 (43%), Gaps = 25/239 (10%)
Query: 161 YSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQ----LVIMASGKRIHKEILFP 215
Y+I V+ D G A + S L +R VLD++ F+ V ++ I +L
Sbjct: 200 YTIEVTATDGG--APQKSGSTTLYIR-VLDFNDNSPTFEHSSLKVELSEDSPIGSRVL-- 254
Query: 216 EPIHAIDQDLGVGATLRYELISGNDR---KLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+HA D D G+ + Y + G+ ++F +D ++G + L+ +D + + ++
Sbjct: 255 -KVHAFDPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETK-----KSY 308
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS------IVENLPNGFSVL 326
L +QAS L ++ R ++++D+NDN PE + + I E V
Sbjct: 309 ELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFVA 368
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ +DKD G NG L+ + S + T LDRE+ S + V +++
Sbjct: 369 LISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTTTLDRESISEYNLTVISED 427
Score = 55.2 bits (127), Expect = 1e-05
Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 17/159 (10%)
Query: 220 AIDQDLGVGATLRYELIS-----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFV 273
A D D G + Y L+ G+ F S+D +GSL+ + D + ++Q
Sbjct: 477 ARDLDAGKNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQ----- 531
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-----ISIVENLPNGFSVLQV 328
V+A+ P ++ +++ ++D NDN P F I I N G+ L+V
Sbjct: 532 FSVKATDKGFPSLSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANTGYLALKV 591
Query: 329 MATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQ 366
A D+D G N E Y L+D FSID +G + ++ +
Sbjct: 592 AAKDEDSGINSELNYHILEDEAKLFSIDKNTGEIILKRK 630
Score = 53.6 bits (123), Expect = 4e-05
Identities = 56/187 (29%), Positives = 83/187 (44%), Gaps = 20/187 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE-KELDLDAEHNLQANTFVLQV 276
I D+D G +R L G++ F L F+ LD E + N V+
Sbjct: 370 ISTSDKDSGPNGYVRTSL-EGHEH--FKLQQAYSDTFMIITTTTLDRESISEYNLTVISE 426
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
P KT + I + D NDN P F Y++S++EN G + V+A D D G
Sbjct: 427 DLG--TPPFKTVK-HYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAG 483
Query: 337 ENGEFTYQLDD---PKGA-----FSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKETN 387
+NG+ +Y L + P G+ S+DP SG L T+R+ D E ++ V A +
Sbjct: 484 KNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRS---FDFETLKDVQFSVKATDKG 540
Query: 388 -PSVVGT 393
PS+ T
Sbjct: 541 FPSLSST 547
Score = 52.0 bits (119), Expect = 1e-04
Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 9/129 (6%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
I V + VKD+NDH P F + + ++ E+A R V A D D G N +Y I
Sbjct: 109 IHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDV-AVDHDVGDNYIQSYHIS-H 166
Query: 1088 DTDLPFEIS-----PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
++ E+S + L + LDRETED Y + V A D G
Sbjct: 167 NSHFVVEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGG-APQKSGSTTLYIRVL 225
Query: 1143 DVNDNSPKF 1151
D NDNSP F
Sbjct: 226 DFNDNSPTF 234
Score = 45.2 bits (102), Expect = 0.014
Identities = 63/264 (23%), Positives = 109/264 (41%), Gaps = 24/264 (9%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG--IYQVTIYIEDENDNPPVFEHATY 792
DG + + +DREK + F+ S + V I ++D ND+ P F
Sbjct: 71 DGLLTVGEVIDREKLCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNET 130
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKF 848
I E++ + + +D A D D G N + Y + + +V D
Sbjct: 131 HLDISEDAPLNSRFPLD---VAVDHDVGDNYIQSYHISHNSHFVVEVSTREDGEKSAELV 187
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
+ SLDRE + Y + + A D G S L I + D NDN P F E+S +++
Sbjct: 188 LIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTF----EHSSLKV-- 241
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPL-FLIPENIPIGTT-IIKLNALDLDSGLNG 964
E + G +++V + F D G + + E P T + +++ + + L
Sbjct: 242 ELSEDSPIGSRVLKV---HAFDPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKD 298
Query: 965 QIRYEFNS--EVYIPPSKLSADAL 986
+ YE E++I S L A+++
Sbjct: 299 IVDYETKKSYELHIQASDLGANSV 322
Score = 37.1 bits (82), Expect = 3.7
Identities = 16/46 (34%), Positives = 26/46 (56%)
Query: 1441 ATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDAGRV 1486
A D D GIN+++ Y IL ++A F+ID +G + + L G +
Sbjct: 593 AKDEDSGINSELNYHILEDEAKLFSIDKNTGEIILKRKLTASCGEI 638
Score = 35.9 bits (79), Expect = 8.6
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 8/86 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVF----VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
L S ++V ++D NDN P F + +N E + NA G + KV A D D G N
Sbjct: 544 LSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSE 603
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTV 520
+ Y + F I+ NTG +
Sbjct: 604 LNYHILEDE----AKLFSIDKNTGEI 625
>UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261;
Euteleostomi|Rep: Cadherin-20 precursor - Homo sapiens
(Human)
Length = 801
Score = 105 bits (251), Expect = 1e-20
Identities = 121/487 (24%), Positives = 196/487 (40%), Gaps = 45/487 (9%)
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
F V E G ++ + S G G+++++++ + G I + LD
Sbjct: 66 FFVLEEYTGT--DPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLD 123
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE+R Y + A + + I I+D NDN P F Y + E S +GT
Sbjct: 124 REERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTS 183
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ A D G +A +Y++ +G+ F VD TGV++ ++DRE K Y++ +
Sbjct: 184 VIQVTATDADDPTYGNSARVVYSIL-QGQPYFSVDSKTGVIRTALMNMDREAKEYYEVII 242
Query: 866 VARD----TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
A+D GGL+ + I + D NDN P F Q ++ ++ + ++ T G
Sbjct: 243 QAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQ--KHYQMSVLESAPISSTVG------ 294
Query: 922 KPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
FA D+D E I +K +D D I + N +V I
Sbjct: 295 ---RVFAKDLD---------EGI---NAEMKYTIVDGDGADAFDISTDPNFQVGI----- 334
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDH 1041
+ VK+ + + + P E R L+ G D +V + V+DV D
Sbjct: 335 ----ITVKKPLSFESKKSYTLKVEGANPHLEMRF----LNLGPFQDTTTVHISVEDV-DE 385
Query: 1042 FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
PVF+ +Y V E + + A D D N+ + SD F + TG
Sbjct: 386 PPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGA 445
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
L LDRE + +TV+A + DVNDN+P+F F E +
Sbjct: 446 LMTARPLDREEFSWHNITVLAMEMN-NPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCE 504
Query: 1162 HPEADEL 1168
+ +A +L
Sbjct: 505 NAKAGQL 511
Score = 82.6 bits (195), Expect = 8e-14
Identities = 114/469 (24%), Positives = 195/469 (41%), Gaps = 47/469 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P F+ Y ++ + VGT + +V A D P G + V+Y + +
Sbjct: 153 IKIQDINDNEPKFLDGP-YVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQ 211
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA-VVTIEVTRG 562
F ++ TG + A ++ + E Q + + LA T+ +T
Sbjct: 212 PY-----FSVDSKTGVIRTALMN-MDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLS 265
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGY-EEGVP 619
+ P P F Y+ V + I ++VG++ D E ++ Y ++ G +
Sbjct: 266 DVNDNP--PRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFD 323
Query: 620 FAVEE--RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT------NATVHV-VDVN 670
+ + + G+ITV LS ++ Y + + + + TVH+ V+
Sbjct: 324 ISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV 383
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
DE V G + V E+ A QI + N ++R+ I D
Sbjct: 384 DEPPVFEPGFY---FVEVPEDVAIGTTIQIISAKDPDVTNN---SIRYSIDRSSDPGRFF 437
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ G + T +PLDRE+ + +TV+A E N S G VTI + D NDN P F
Sbjct: 438 YVDITTGALMTARPLDREEFSWHNITVLAMEMNNP--SQVGSVPVTIKVLDVNDNAPEFP 495
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL-FMYTLFGEGKE-----MFDVDEN 842
YE F+ EN+K G I+ + A D D+ N F Y+L E + D +N
Sbjct: 496 RF-YEAFVCENAKAGQLIQ---TVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDN 551
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN 889
T + ++++ ++ L ++ D+G LSS L I + +D+
Sbjct: 552 TARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
Score = 71.7 bits (168), Expect = 1e-10
Identities = 90/348 (25%), Positives = 152/348 (43%), Gaps = 31/348 (8%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGVP-FAVEERSGV 628
P F+ PY V +GTSV Q+ DA + S +++ +G P F+V+ ++GV
Sbjct: 163 PKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGV 222
Query: 629 I-TVVDDLSRYNRPMYDFEAVALQENANLS-IVTNATVHVV--DVNDERGVLLKGAHSPI 684
I T + ++ R + Y+ A L + TV++ DVND + +
Sbjct: 223 IRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMS 282
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-----GTIF 739
+ ++ + +G++F ++ +++ I + D D I+ D G I
Sbjct: 283 V--LESAPISSTVGRVFAKDLDE---GINAEMKYTIVDG-DGADAFDISTDPNFQVGIIT 336
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGV---ISGAGIYQ--VTIYIEDEN-DNPPVFEHATYE 793
+KPL E + Y + V N + G +Q T++I E+ D PPVFE Y
Sbjct: 337 VKKPLSFESKKSYTLKVEGA-NPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYF 395
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNAL-FMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ E+ IGT I+ II A D D N++ + + F VD TG +
Sbjct: 396 VEVPEDVAIGTTIQ---IISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGAL-MTARP 451
Query: 853 LDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEE 898
LDRE+ + ++++A + S + I + D NDN PEF + E
Sbjct: 452 LDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYE 499
Score = 61.7 bits (143), Expect = 2e-07
Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 28/359 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V +TL D NDN P F P Y+ S+ +A + + +G+V A D D G N + Y
Sbjct: 254 LAGTTTVNITLSDVNDNPPRF-PQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYT 312
Query: 499 LQRTSNLTITSPFKINPN--TGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
+ +PN G ++V + E + + ++ + ANP L +
Sbjct: 313 IVDGDGAD-AFDISTDPNFQVGIITVKKPLSFESKKSYTLKV--EGANPHLEMRFLNLGP 369
Query: 557 IEVTRGTKGNKPDI---PDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLH 612
+ T + D+ P F Y V +V IGT++ I D N + Y +
Sbjct: 370 FQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDR 429
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN--ATVHVVDVN 670
+ G F V+ +G + L R ++ +A++ N N S V + T+ V+DVN
Sbjct: 430 SSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMN-NPSQVGSVPVTIKVLDVN 488
Query: 671 DERGVLLKGAHSPIIFHVKEN---SAGAAIGQIFHTNMSSIY----GNGTGNVRFLIANQ 723
D + + + + K +A+ Q N Y N F I +
Sbjct: 489 DNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDN 548
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDEN 781
QD T I G F Q +++ V+ + + IA+ + V+S G + + D++
Sbjct: 549 QDNTARILTRRSG--FRQ-----QEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
Score = 61.7 bits (143), Expect = 2e-07
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I A D D+ ++RY + +D + F +D G+L + LD + + + + V
Sbjct: 411 ISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE-----EFSWHNITV 464
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A ++NNP + V I++LD+NDN PEF FY + EN G + V A D+D
Sbjct: 465 LAMEMNNPSQVGSVPVTIKVLDVNDNAPEFP-RFYEAFVCENAKAGQLIQTVSAVDQDDP 523
Query: 337 ENGEFTYQLDDPKGA 351
NG+ Y P+ A
Sbjct: 524 RNGQHFYYSLAPEAA 538
Score = 59.7 bits (138), Expect = 6e-07
Identities = 50/185 (27%), Positives = 89/185 (48%), Gaps = 14/185 (7%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLD--AEHNLQAN 270
L+ +H+ D D G G+ ++Y L +F++D G + + LD + A++ L+A
Sbjct: 78 LYVGKLHS-DMDRGDGS-IKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRA- 134
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
Q + P++ ++ I++ D+NDN P+F Y ++ E P G SV+QV A
Sbjct: 135 ----QALDRRTGRPMEP-ESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTA 189
Query: 331 TDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
TD D G + Y + + FS+D ++G + +DREA + + AK+
Sbjct: 190 TDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMN-MDREAKEYYEVIIQAKDMG 248
Query: 388 PSVVG 392
+ G
Sbjct: 249 GQLGG 253
Score = 58.0 bits (134), Expect = 2e-06
Identities = 52/170 (30%), Positives = 79/170 (46%), Gaps = 16/170 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A + Y ++ G + FS+DS G + +++D E + + +QA
Sbjct: 192 ADDPTYGNSARVVYSILQG--QPYFSVDSKTG-VIRTALMNMDREAK---EYYEVIIQAK 245
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ L V I L D+NDN P F Y +S++E+ P +V +V A D D+G
Sbjct: 246 DMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGI 305
Query: 338 NGEFTYQLDDPKGA----FSIDP--RSGWLTVRNQTVLDREAHSSLRMKV 381
N E Y + D GA S DP + G +TV+ L E+ S +KV
Sbjct: 306 NAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKP--LSFESKKSYTLKV 353
Score = 50.8 bits (116), Expect = 3e-04
Identities = 50/186 (26%), Positives = 83/186 (44%), Gaps = 14/186 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVN----GSLFLEKELDLDAE--HNLQANT 271
+ A D D G+ A ++Y ++ G+ F + + G + ++K L +++ + L+
Sbjct: 296 VFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEG 355
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
++ LN V I + D+ D P FE FY + + E++ G ++ + A
Sbjct: 356 ANPHLEMRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAK 414
Query: 332 DKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TN 387
D D N Y +D DP F +D +G L LDRE S + V A E N
Sbjct: 415 DPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARP--LDREEFSWHNITVLAMEMNN 471
Query: 388 PSVVGT 393
PS VG+
Sbjct: 472 PSQVGS 477
Score = 48.0 bits (109), Expect = 0.002
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVA 1352
YIL+ I F ID G ++ ++ DRE + Y + +A ++ R + P +
Sbjct: 96 YILSGEGAGI--VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPME----PES 149
Query: 1353 EDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHP 1412
E +++I+D+NDN PKF +G P V +P +P G V+Q+ P
Sbjct: 150 E------------FIIKIQDINDNEPKFLDG--PYVATVPEMSPVGTSVIQVTATDADDP 195
Query: 1413 TASRTVR 1419
T + R
Sbjct: 196 TYGNSAR 202
Score = 46.4 bits (105), Expect = 0.006
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 18/148 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE++ IGTTI ++A D D N IRY + S+D R+F ++ G
Sbjct: 398 VPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDR---------SSDP---GRFFYVDITTG 444
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
++ AR L E S + + A++ N + SV V +K DVND+ P F + + F E
Sbjct: 445 ALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCE 504
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYF 1083
A+ +++ V A D D +N Y+
Sbjct: 505 NAK-AGQLIQTVSAVDQDDPRNGQHFYY 531
Score = 40.3 bits (90), Expect = 0.40
Identities = 16/29 (55%), Positives = 21/29 (72%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ I+D+NDN P FLD PY TV E++P G
Sbjct: 153 IKIQDINDNEPKFLDGPYVATVPEMSPVG 181
Score = 38.7 bits (86), Expect = 1.2
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 6/106 (5%)
Query: 1049 WYNFNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
W F V E +YT +GK+ + D D G + ++ Y + + F I TG +
Sbjct: 63 WNQFFVLE-EYTGTDPLYVGKLHS-DMDRG-DGSIKYILSGEGAGIVFTIDDTTGDIHAI 119
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE +Y L A D D+NDN PKF
Sbjct: 120 QRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
>UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p -
Drosophila melanogaster (Fruit fly)
Length = 1820
Score = 104 bits (250), Expect = 2e-20
Identities = 248/1032 (24%), Positives = 420/1032 (40%), Gaps = 127/1032 (12%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ--NGMVLYDLQR 501
N+ V + D NDN+P F S Y +++ A + V+A D D NG V Y +
Sbjct: 570 NLFVGVTDVNDNHPNF-ESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIV- 627
Query: 502 TSNLTITSPFKINPNTGTVSV---AESPILE-GRHALFVEASD---QPANPSER---RYS 551
+ N + F+I P+TG + + A S E G + L V A+D P + + R R
Sbjct: 628 SENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVG 687
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL 610
++ + RG N ++P +G P Y + N G++V + +D + +
Sbjct: 688 ISGNQRPIFRGHFQNMENLP-IIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDSLLRYR 746
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRP--MYDFEAVALQENANLSIVTNAT----V 664
+ G + F ++E SG+ITV +R +R M FE + ++ I AT V
Sbjct: 747 IVGANDN--FEIDEISGLITVSPQ-ARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYV 803
Query: 665 HVVDVNDERGVLLKGAHSPIIFH---VKENSAGA-AIGQIFHTNMS-SIYGN--GTGNVR 717
+V D+NDER + +++ + V E+ AI + ++ + S+ G T
Sbjct: 804 NVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPVAATTKAG 863
Query: 718 FLIANQQDVTDDIAIAED---GTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGI--Y 771
IAN+ + A D G IF L + + TV + + N V +
Sbjct: 864 VSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTT 923
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+VT+Y++ D PVF++ G+ I +IK + I + ALF+
Sbjct: 924 EVTVYVQSFQDTNPVFKNT---GWTSSRPVIDVKIKEEMPIDS--------ALFIL---- 968
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII-MIGDENDNK 890
+ D + F L K++ Y VA TG + + L +GD
Sbjct: 969 ---QAEDPVTRQPITSF---ELIEPKQVDY--FQVAERTGEVILKKRLDYEALGDTG--- 1017
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
PEF +VR + + T I V+ N + ++ I EN P +
Sbjct: 1018 PEFEL-----QVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERV 1072
Query: 951 IKLNALDLDSGLNGQI-RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP 1009
I++ ALD D+ LN + R ++ +Y L E F IN G +IVA
Sbjct: 1073 IRVRALDKDAVLNARDERLGYHKIIY----SLQG---EHAMLFDINNTTGEIIVASGQTI 1125
Query: 1010 ESE----FRLNISALDG-GNLNDN----ISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQY 1059
+ E +L I A D G D + +++ V DVND+ P F + Y+ + E AQ
Sbjct: 1126 DRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQI 1185
Query: 1060 TRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGEL-DRETEDKYI 1117
VL +++A DAD G + Y + + + F+I +G++S L + Y+
Sbjct: 1186 DSFVL-QLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYV 1244
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVM 1177
L V A+DNG DV A D + + P +++N +V
Sbjct: 1245 LIVRAQDNG---NQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVT 1301
Query: 1178 MIPVYKATI----EENAPIGTTVAKVFANDTD----FIGNGNGLILYSLPQRKNQQNL-- 1227
PV++ +E+ P GT ++ + D I +GLI + +++
Sbjct: 1302 GAPVFQVIASDPDDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYR 1361
Query: 1228 --------GLPSLSSTAILMVTVADVPD-EVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
G P S+T IL + + DV D E + + + EE V S
Sbjct: 1362 ILLEVSDNGQPKQSATRILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFS 1421
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP---DREVKDTYEVIVRA 1335
+ EN + Y I++ N+ + F I+ N +L ++++ DRE +++ + ++
Sbjct: 1422 ALDEDLGENAAIDYVIIDGNNEQL---FTIERNNESLAILKTKKPIDREQVESFTLTIKC 1478
Query: 1336 ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTA 1395
+L Y D + +++ VR+ D++DN PKF + P V I
Sbjct: 1479 ------LKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKFEQPD-PTV-GIRINV 1530
Query: 1396 PFGYQVMQLKGA 1407
P V LK +
Sbjct: 1531 PIDTVVTTLKAS 1542
Score = 99.1 bits (236), Expect = 8e-19
Identities = 123/515 (23%), Positives = 221/515 (42%), Gaps = 60/515 (11%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM- 494
D Q + V +T+ + NDN+P F N Y+ ++ N + +V+A+D D N
Sbjct: 1030 DRQRSTVSRVNITVENVNDNSPRF-ERNSYQATIIENRPHPERVIRVRALDKDAVLNARD 1088
Query: 495 -------VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG----RHALFVEASDQPA 543
++Y LQ + F IN TG + VA ++ R L ++A D P
Sbjct: 1089 ERLGYHKIIYSLQGEHAML----FDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPG 1144
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE- 602
P++ + S+ + IEV + P+F Y + N I + V Q+ DA E
Sbjct: 1145 RPTDAKQSVVELQIEVL----DVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEG 1200
Query: 603 -QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN------ 655
+V Y+L++ E F ++ +SG+I+ +L+ R V Q+N N
Sbjct: 1201 LGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQP 1260
Query: 656 -LSIVTNATVHVVDVNDERGV-LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNG 712
LS T+ +++ DV+ GV + +V EN+ GA + Q+ ++
Sbjct: 1261 TLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDD-ESTP 1319
Query: 713 TGNVRF-LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGI 770
+G + + ++ + D + A G I T++ +DRE +D+YR+ + +++ + S I
Sbjct: 1320 SGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRI 1379
Query: 771 YQVTIYIEDENDNPPVFEHATYEG----FIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
Q+ I D +D+ P F G + E GT + A D D G NA
Sbjct: 1380 LQIAIL--DVDDHEPRFAREAGAGPLSMSVREEEPAGTIV---GNFSALDEDLGENAAID 1434
Query: 827 YTLF-GEGKEMFDVDENTGVVKFIGDS--LDREKKIMYKLSLVARDTG--GLS------- 874
Y + G +++F ++ N + + +DRE+ + L++ G G
Sbjct: 1435 YVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYD 1494
Query: 875 ----SEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
S + + + D +DN P+F Q + +RI+
Sbjct: 1495 RQDLSHLRINVRVLDIDDNLPKFEQPDPTVGIRIN 1529
Score = 83.4 bits (197), Expect = 4e-14
Identities = 122/511 (23%), Positives = 212/511 (41%), Gaps = 61/511 (11%)
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
P + T + + D +L S + + ++D D P+F + Y ++ N G I
Sbjct: 208 PSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAP-YSATVPENTPAGVSILT 266
Query: 482 VKAVDPDLGQNGMVLYDLQRT--SNLTITSPFKINPNTGT--VSVAESP-------ILE- 529
VKAVD D+G + L+ + + PF +P GT + P IL+
Sbjct: 267 VKAVDGDVGIPREIFLSLEDEPFGHFELV-PFG-DPRDGTAVLQTTSEPLDRENAEILQN 324
Query: 530 -GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
G + + A++ +SL VTI VT P F G + + N+
Sbjct: 325 GGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQ----PTFSGPHFNVSITENLAN 380
Query: 589 GTSVGQIRV----NDAFEQNDVSYDLLHGYEEGVPFAV-----EERSGVITVVDDLSRYN 639
G + + + D E + L + F V + R+ V+ V + SR +
Sbjct: 381 GMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLD 440
Query: 640 RPMYD-------FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
+ D F+ VA + + T +H++D ND V +G + F EN
Sbjct: 441 YDVVDPDLRKFEFDLVASVKGVEKA-KTRVEIHLLDANDNAPVFDQGTYR---FTAAENL 496
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDV 751
AI I H + + G+VR+++ D+ + E G ++ KPLD EK+
Sbjct: 497 PVDAI--IGHVKATDLDSGEFGHVRYVLKGFG--ADNFYVNPETGGVYLLKPLDYEKQSS 552
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
Y +TV+A + A ++ + + D NDN P FE Y I E + + +
Sbjct: 553 YSLTVVAIDGGQREANANLF---VGVTDVNDNHPNFESKEYSRTIREGAAL---FEPQFF 606
Query: 812 IKATDADEGT--NALFMYTLFGEGK---EMFDVDENTG--VVKFIGDSLDREKKIMYKLS 864
++A DAD + N Y++ E +F ++ +TG V++ S+D E+ Y+L
Sbjct: 607 VRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERG-EYELV 665
Query: 865 LVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ A D G LS+ +++ +G + +P F
Sbjct: 666 VSATDFGIPPLSNTTRVLVRVGISGNQRPIF 696
Score = 81.8 bits (193), Expect = 1e-13
Identities = 130/487 (26%), Positives = 197/487 (40%), Gaps = 49/487 (10%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIG---KVKAVDPDLGQNGMV-LYDLQRTSNLTI- 507
NDN P F+ Y S+ + VG+ + + VD D G N V + L+ I
Sbjct: 122 NDNQPTFL-GRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIF 180
Query: 508 -TSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
KI+ T VA L E R + + S + R SLA ++I V
Sbjct: 181 EVRAVKISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVI--DI 238
Query: 565 GNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH---GYEEGVP 619
++P P F APY V N G S+ ++ D ++ L G+ E VP
Sbjct: 239 QDQP--PIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVP 296
Query: 620 FAVEERSGVI---TVVDDLSRYNRPM--------YDFEAVALQENANLS--IVTNATVHV 666
F + R G T + L R N + + A L + A + +T T+ V
Sbjct: 297 FG-DPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVV 355
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSA-GAAI-GQIFHTNMSSIYGNGTGNVRFL-IANQ 723
DV+D + G H + + EN A G + G + + N + + N
Sbjct: 356 TDVDDHQPTF-SGPHFNV--SITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNA 412
Query: 724 QDVTDDIAIAEDG-TIFTQKPLDREKRDVYRMTV-IAEFNKGVISGA-GIYQ----VTIY 776
V + G T K L+ + D + + +F +++ G+ + V I+
Sbjct: 413 ARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIH 472
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D NDN PVF+ TY EN + I +KATD D G Y L G G +
Sbjct: 473 LLDANDNAPVFDQGTYRFTAAENLPVDAII---GHVKATDLDSGEFGHVRYVLKGFGADN 529
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F V+ TG V ++ LD EK+ Y L++VA D G + A L + + D NDN P F
Sbjct: 530 FYVNPETGGV-YLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESK 588
Query: 897 EENSKVR 903
E + +R
Sbjct: 589 EYSRTIR 595
Score = 70.5 bits (165), Expect = 3e-10
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 5/160 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A D+ LG + Y L G LF +++ G + + +D E + +
Sbjct: 1084 LNARDERLGYHKII-YSL-QGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAED 1141
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ K + ++IE+LD+NDN PEF Y+ I EN VLQ+ A D D+G
Sbjct: 1142 SPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGL 1201
Query: 338 NGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
GE Y+L + G F ID +SG ++ R AH
Sbjct: 1202 GGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAH 1241
Score = 67.7 bits (158), Expect = 2e-09
Identities = 43/135 (31%), Positives = 70/135 (51%), Gaps = 8/135 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + LRY ++ ND F +D ++G + + + +D + N+ N+F + V
Sbjct: 731 VSAHDPD-GLDSLLRYRIVGANDN--FEIDEISGLITVSPQARIDRDSNM--NSFEIIVN 785
Query: 278 ASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P+ +TA V + + D+ND P+FE + Y + E G SVL+V A DKD
Sbjct: 786 AVDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDL- 844
Query: 337 ENGEFTYQLDDPKGA 351
N + Y + P A
Sbjct: 845 -NSKLEYSMVGPVAA 858
Score = 67.3 bits (157), Expect = 3e-09
Identities = 45/144 (31%), Positives = 64/144 (44%), Gaps = 4/144 (2%)
Query: 1008 PPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
P +F ++ A G V + + D ND+ PVF + Y F E ++G V
Sbjct: 446 PDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHV 505
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX 1127
ATD D G+ ++ Y ++ D F ++P TG + + LD E + Y LTVVA D G
Sbjct: 506 KATDLDSGEFGHVRYVLKGFGAD-NFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGG- 563
Query: 1128 XXXXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 564 --QREANANLFVGVTDVNDNHPNF 585
Score = 63.7 bits (148), Expect = 4e-08
Identities = 47/163 (28%), Positives = 80/163 (49%), Gaps = 11/163 (6%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+ELI F + G + L+K LD +A + F LQV+A+ + T +RV
Sbjct: 982 FELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPE-FELQVRANSADRQRSTV-SRV 1039
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG--------EFTYQ 344
I + ++NDN P FE + Y +I+EN P+ V++V A DKD N + Y
Sbjct: 1040 NITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKIIYS 1099
Query: 345 LDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
L F I+ +G + V + +DRE +++++ A+++
Sbjct: 1100 LQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDS 1142
Score = 61.7 bits (143), Expect = 2e-07
Identities = 76/292 (26%), Positives = 122/292 (41%), Gaps = 42/292 (14%)
Query: 77 ISAYLSVTVYIEDV--NDNVPIFLD--TPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
+S V +YI DV ND VP FL V E TG F + + T
Sbjct: 1262 LSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSG 1321
Query: 133 TVP-RGLTIFKDIRAF----------DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
T+ R L D AF R + D++ ++ +D+G ++
Sbjct: 1322 TITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATR--- 1378
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEP-------IHAIDQDLGVGATLRYE 234
+L +LD D D E + A + + EP A+D+DLG A + Y
Sbjct: 1379 ILQIAILDVD--DHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYV 1436
Query: 235 LISGNDRKLFSLDSVNGSL-FLEKELDLDAEHNLQANTFVLQVQASQLNNP--------- 284
+I GN+ +LF+++ N SL L+ + +D E Q +F L ++ +L P
Sbjct: 1437 IIDGNNEQLFTIERNNESLAILKTKKPIDRE---QVESFTLTIKCLKLGEPGYKFIGDPY 1493
Query: 285 --LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ R+ + +LD++DNLP+FE + I N+P V + A+D D
Sbjct: 1494 DRQDLSHLRINVRVLDIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDAD 1545
Score = 61.3 bits (142), Expect = 2e-07
Identities = 79/278 (28%), Positives = 109/278 (39%), Gaps = 40/278 (14%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F EN+P+ I + A DLDSG G +RY AD F +N
Sbjct: 490 FTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKG--------FGADN------FYVNPE 535
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
G V + + L E S + L + A+DGG N ++ V V DVND+ P F+ Y+ +
Sbjct: 536 TGGVYLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIR 595
Query: 1056 EAQYTRRVLGKVDATDADFGQ--NANLTYFI--QPSDTDLPFEISPLTGVLSV-NGELDR 1110
E V A DAD N + Y I + S F I P TG + +
Sbjct: 596 EGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSM 655
Query: 1111 ETE-DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
+TE +Y L V A D G N P F +
Sbjct: 656 DTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQR-PIFRGHFQ------------- 701
Query: 1170 NHNFESVMMI--PVYKATIEENAPIGTTVAKVFANDTD 1205
N E++ +I P Y+ +I ENA G+ V V A+D D
Sbjct: 702 --NMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD 737
Score = 60.5 bits (140), Expect = 3e-07
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 21/177 (11%)
Query: 218 IHAIDQDLGVGATLRYELIS-GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A+D D G+G +RYEL++ G LF +D+ +G + + L +A+ +VL V
Sbjct: 1192 LEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKG----RAHPYVLIV 1247
Query: 277 QASQLNN-----PLKTAQARVEIELLDL--NDNLPEFEVDFYN--ISIVENLPNGFSVLQ 327
+A N P + V I + D+ ND +P F ++ EN G V Q
Sbjct: 1248 RAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQ 1307
Query: 328 VMATDKDQGE--NGEFTYQL--DDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
V+A+D D +G TY++ D P AF ID SG +T R +DRE R+
Sbjct: 1308 VIASDPDDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQS--MDRETKDMYRI 1362
Score = 59.7 bits (138), Expect = 6e-07
Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 22/181 (12%)
Query: 208 IHKEILFPEPIHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGS-------LFLEKEL 259
+ E+ PI +D+D G+ + ++ + + ND +F + +V S + L+++L
Sbjct: 143 VGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQL 202
Query: 260 DLDAEHNLQANTFVLQVQASQ--LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE 317
D ++ + ++L + AS L+N L + A + I ++D+ D P F Y+ ++ E
Sbjct: 203 DFESRPS-----YILTISASDSALDNRLSSL-ATISINVIDIQDQPPIFTNAPYSATVPE 256
Query: 318 NLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSI----DPRSGWLTVRNQT-VLDR 371
N P G S+L V A D D G E L D+P G F + DPR G ++ + LDR
Sbjct: 257 NTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDR 316
Query: 372 E 372
E
Sbjct: 317 E 317
Score = 58.8 bits (136), Expect = 1e-06
Identities = 38/100 (38%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 285 LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
++ A+ RVEI LLD NDN P F+ Y + ENLP + V ATD D GE G Y
Sbjct: 462 VEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYV 521
Query: 345 LDD-PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
L F ++P +G + + LD E SS + V A
Sbjct: 522 LKGFGADNFYVNPETGGVYLLKP--LDYEKQSSYSLTVVA 559
Score = 56.8 bits (131), Expect = 4e-06
Identities = 152/648 (23%), Positives = 253/648 (39%), Gaps = 98/648 (15%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVIS---GAGIYQVTIYIEDENDNPPVFEHA 790
E G + ++ LDRE +D + +I+ ++G+ + I + NDN P F
Sbjct: 73 ETGVVRLRQELDRETQDTVEV-IISITDEGIYGTEPNTVSQRRVIPVRYYNDNQPTFLGR 131
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK--EMFDV------DEN 842
Y + E+ +G+E+ ++ I D DEG N+ E ++F+V D N
Sbjct: 132 PYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGN 191
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDT---GGLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ LD E + Y L++ A D+ LSS A + I + D D P F +
Sbjct: 192 YTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYS 251
Query: 900 SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD 959
+ V N AG +I+ VK + DV +FL E+ P G +
Sbjct: 252 ATV------PENTPAGVSILTVKAVDG---DVGIPREIFLSLEDEPFG----HFELVPFG 298
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISA 1019
+G + SE P + +A+ L+ +V + R +I ++P E
Sbjct: 299 DPRDGTAVLQTTSE---PLDRENAEILQNGGVYVFSIRATELIDG-AIPAEHSL------ 348
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG--KVDATDADFGQN 1077
V + V DV+DH P F +N ++ E L + D D G+N
Sbjct: 349 ---------TRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGEN 399
Query: 1078 ANLTYFIQP-SDTDLPFEISPLTG------VLSV--NGELDRETED----KYILTVVARD 1124
+ ++ + FE+SP V+ V LD + D K+ +VA
Sbjct: 400 SRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASV 459
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA 1184
G D NDN+P FD+ ++ A+ N +I KA
Sbjct: 460 KG---VEKAKTRVEIHLLDANDNAP---VFDQ-GTYRFTAAE-----NLPVDAIIGHVKA 507
Query: 1185 TIEENAPIGTT--VAKVFANDTDFIGNGNGLILYSLP---QRKNQQNLGLPSL-----SS 1234
T ++ G V K F D ++ G + P ++++ +L + ++ +
Sbjct: 508 TDLDSGEFGHVRYVLKGFGADNFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQREA 567
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTE--HYENFKM 1290
A L V V DV D + P F S+ Y I E + P V + + N ++
Sbjct: 568 NANLFVGVTDVND-----NHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRV 622
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYL---VRSPDREVKDTYEVIVRA 1335
+Y I++EN F I+P G + + RS D E + YE++V A
Sbjct: 623 KYSIVSENSI-AGNVFRIEPDTGEIVIQKAARSMDTE-RGEYELVVSA 668
Score = 52.8 bits (121), Expect = 7e-05
Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 12/142 (8%)
Query: 218 IHAIDQDLGVGATLRYELIS---GNDRKLFSLDSVNGSLFLE---KELDLDAEHNLQ-AN 270
+ A+D D+G+ + L G+ + D +G+ L+ + LD + LQ
Sbjct: 267 VKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGG 326
Query: 271 TFVLQVQASQLNN---PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV-- 325
+V ++A++L + P + + RV I + D++D+ P F +N+SI ENL NG +
Sbjct: 327 VYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPG 386
Query: 326 LQVMATDKDQGENGEFTYQLDD 347
L + D+D GEN + L D
Sbjct: 387 LSIFVDDRDMGENSRYELSLRD 408
Score = 46.0 bits (104), Expect = 0.008
Identities = 109/515 (21%), Positives = 200/515 (38%), Gaps = 73/515 (14%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + EN P+G+ + +L D + G +++Y + V+ + L R + E
Sbjct: 34 FSLSENTPVGSPVFQLKGTDPEGG---RLKYSISGPVFSVDRETGVVRL---RQELDRET 87
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V V S+ E + + + + I VR + ND+ P F Y +V E+
Sbjct: 88 QDTVEVIISITDEGIYGTEPNTVSQRRV---IPVRYY----NDNQPTFLGRPYTASVSES 140
Query: 1058 QYTRRVLG---KVDATDADFGQNANLTY-FIQPSDTDLPFEISPL-------TGVLSVNG 1106
L + D D G N+ + ++ +D FE+ + T +++
Sbjct: 141 LPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQ 200
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY-------------A 1153
+LD E+ YILT+ A D+ D+ D P F A
Sbjct: 201 QLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPA 260
Query: 1154 FDELLEWKHPEAD---------ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
+L K + D L + F ++P + + A + TT + +
Sbjct: 261 GVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVP-FGDPRDGTAVLQTTSEPLDRENA 319
Query: 1205 DFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
+ + NG G+ ++S+ + +P+ S + + V DV D +P F ++ +
Sbjct: 320 EILQNG-GVYVFSIRATELIDG-AIPAEHSLTRVTIVVTDVDDH-----QPTFSGPHFNV 372
Query: 1265 EIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNG---TLYLVR 1319
I EN+ P+ +S+ + + RY + + + R F + P T +V+
Sbjct: 373 SITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVK 432
Query: 1320 SPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
+ D Y+V V + +K+ +L VA ++G+ K +V + + D NDN+P
Sbjct: 433 VLNASRLD-YDV-VDPDLRKFEFDL------VAS--VKGVEKAKTRVEIHLLDANDNAPV 482
Query: 1380 FTNGNRPLVTA--IPTTAPFGY-QVMQL-KGAIGH 1410
F G A +P A G+ + L G GH
Sbjct: 483 FDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGH 517
Score = 44.8 bits (101), Expect = 0.018
Identities = 37/168 (22%), Positives = 78/168 (46%), Gaps = 13/168 (7%)
Query: 222 DQDLGVGATLRYELISGN-DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ 280
D + T+ Y ++ D + F +D+ +G + + +D + + + + + ++ S
Sbjct: 1314 DDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETK-----DMYRILLEVSD 1368
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDF----YNISIVENLPNGFSVLQVMATDKDQG 336
P ++A ++I +LD++D+ P F + ++S+ E P G V A D+D G
Sbjct: 1369 NGQPKQSATRILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLG 1428
Query: 337 ENGEFTYQLDDPKG--AFSIDPRSGWLTV-RNQTVLDREAHSSLRMKV 381
EN Y + D F+I+ + L + + + +DRE S + +
Sbjct: 1429 ENAAIDYVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTI 1476
Score = 42.3 bits (95), Expect = 0.099
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW 360
+NLP Y +SI EN G +V V A D D G + Y++ F ID SG
Sbjct: 704 ENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGANDNFEIDEISGL 762
Query: 361 LTVRNQTVLDREAH-SSLRMKVYAKETNPSVVGT 393
+TV Q +DR+++ +S + V A ++ + T
Sbjct: 763 ITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPET 796
Score = 41.1 bits (92), Expect = 0.23
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 9/116 (7%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G L+Y ISG +FS+D G + L +ELD + + ++ + + P
Sbjct: 56 GGRLKYS-ISG---PVFSVDRETGVVRLRQELDRETQDTVEVIISITD-EGIYGTEPNTV 110
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL---QVMATDKDQGENGE 340
+Q RV I + NDN P F Y S+ E+LP G + ++ D+D+G N E
Sbjct: 111 SQRRV-IPVRYYNDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSE 165
Score = 39.9 bits (89), Expect = 0.53
Identities = 15/39 (38%), Positives = 25/39 (64%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
N++S+ ++++ + D+ D PIF + PY TV E TP G
Sbjct: 223 NRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAG 261
Score = 38.3 bits (85), Expect = 1.6
Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 16/154 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G +RY ++ G F ++ G ++L K LD + + +++ L V
Sbjct: 505 VKATDLDSGEFGHVRY-VLKGFGADNFYVNPETGGVYLLKPLDYEKQ-----SSYSLTVV 558
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD--- 334
A ++ + A A + + + D+NDN P FE Y+ +I E V A D D
Sbjct: 559 A--IDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPS 616
Query: 335 QGENGEFTYQLDDPK----GAFSIDPRSGWLTVR 364
QG NG Y + F I+P +G + ++
Sbjct: 617 QG-NGRVKYSIVSENSIAGNVFRIEPDTGEIVIQ 649
Score = 37.9 bits (84), Expect = 2.1
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 9/85 (10%)
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
D S+ EN P G V Q+ TD E G Y + P FS+D +G + +R +
Sbjct: 30 DMSRFSLSENTPVGSPVFQLKGTDP---EGGRLKYSISGP--VFSVDRETGVVRLRQE-- 82
Query: 369 LDREAHSSLRMKVYAKETNPSVVGT 393
LDRE + ++V T+ + GT
Sbjct: 83 LDRETQDT--VEVIISITDEGIYGT 105
Score = 35.9 bits (79), Expect = 8.6
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 133 TVPRGLTIFKD---IRAFDRDKPNTPNSDVHYSIVSGND--DGHFALESSHKPVLLLRKV 187
T+ G +F+ +RA D D P+ N V YSIVS N F +E +++ +
Sbjct: 593 TIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAA 652
Query: 188 LDYDAGDKEFQLVIMAS 204
D E++LV+ A+
Sbjct: 653 RSMDTERGEYELVVSAT 669
>UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3;
Caenorhabditis|Rep: Cadherin-related hmr-1 precursor -
Caenorhabditis elegans
Length = 2920
Score = 104 bits (250), Expect = 2e-20
Identities = 220/990 (22%), Positives = 382/990 (38%), Gaps = 117/990 (11%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V++ + + D NDN P F LY ++ + + I KV AVD D G N + Y +
Sbjct: 624 SHVDLTIRIDDVNDNVPTFTRP-LYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVD 682
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
N +I S +I+ ++ L RH FV + A SL+ +
Sbjct: 683 N-HNFSINSNGEISAKVRL----DADQLNERH--FVYRFNVTARDHGEPVSLSSSAMIHI 735
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP- 619
R N + Y +V + GT V QI+ DA ++++V+Y +
Sbjct: 736 RTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDA-DRDEVTYSFMDKNGRSTQK 794
Query: 620 ---FAVEERSGVITV-----VDDLSRYNRPMYDFEAVALQENANLSIVTNAT-------- 663
F+++E +G++ + DL+ P+ V +Q++ + + + T
Sbjct: 795 MNLFSIDEHTGLVKLRHGVSAADLAEAENPIN--LTVIVQDDGSCCVYPSKTHTSYATLL 852
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIAN 722
+ + DVN+ + A I + E + I + + G++ + L
Sbjct: 853 IGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYT 912
Query: 723 QQDVTDDIAIAEDGTIFTQKP---LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
Q + I + T P DRE R +TV A ++G G Q ++ + D
Sbjct: 913 QSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKAT-DRGDRPLIGFCQFSVEVVD 971
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
NDN P FE +YE + +GT + + A D D NA Y+L ++
Sbjct: 972 INDNSPQFERPSYETSVSRFEAVGTSV---ITVFAFDNDAAHNAEITYSL--------EI 1020
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN 899
D G + + + LV R +G E LI I K FN I ++
Sbjct: 1021 DTTAG---------EEHQNDLDFFELVNRRSG----EITLIKPI-PMKTQKFIFNVIADD 1066
Query: 900 SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD 959
+ + ++ T +++ + K P + EN+ + I++ A+
Sbjct: 1067 NGIPEALQSSAQVT--LNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSG 1124
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNI 1017
N + Y+ + P +K + + ++ NE V++ L E + + L +
Sbjct: 1125 DSRNSDVIYKLTASGG-PGNKAESKFRQFNKFENGNE-WVEVVIMEGLDYEQVNNYTLTL 1182
Query: 1018 SALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA----QYTRRVLGK----VD 1068
+A D + + V V+DVND P F + ++E ++ + GK V
Sbjct: 1183 TATDMTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVK 1242
Query: 1069 ATDADF-GQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
A D D G + Y I + F I LTG + N + DRE D YILTV A D
Sbjct: 1243 AIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASD 1302
Query: 1125 N------GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
G DVNDN+P F + K E + H+ ++
Sbjct: 1303 RSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGE---GHDVITIKA 1359
Query: 1179 IPVYKATIEENAPIGTTVAKV-FANDTDFIGNGNGLILYSLP---QRKNQQNLGLPSL-- 1232
+ K + IG ++ F TD +G I P + +Q +L L +
Sbjct: 1360 HDLDKHSNLRYHLIGAGGGRIPFGVRTD-----SGTIFVKEPLDFEASDQYHLVLIASDG 1414
Query: 1233 --SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKM 1290
++T + + + DV D ++ +Y IEE+V+ P L +++ T+ ++ K
Sbjct: 1415 RHNATTNVYIHIEDVNDNAPQFEQ----QKYATTVIEEDVDIPKVLFNVHATDADQDEKS 1470
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
+ F I +GT+ LV++ DR+ A + + +
Sbjct: 1471 SRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPP--------AGVPSW-----NFVVQ 1517
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+D G+ Y V V ++D+NDNSP F
Sbjct: 1518 AIDDDGNGLVGY-ADVQVNVRDINDNSPIF 1546
Score = 93.9 bits (223), Expect = 3e-17
Identities = 174/696 (25%), Positives = 271/696 (38%), Gaps = 76/696 (10%)
Query: 476 GTVIGKVKAVDPDL-GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRH 532
G I VKA+D D G V Y + +N T F+I+ TG + E E +
Sbjct: 1235 GKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMY 1294
Query: 533 ALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV 592
L VEASD+ + ++V + P F Y V + G G V
Sbjct: 1295 ILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDV 1354
Query: 593 GQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
I+ +D + +++ Y L+ +PF V SG I V + L Y +A
Sbjct: 1355 ITIKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG 1414
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG 712
N + TN +H+ DVND + ++ + ++E+ I ++ ++
Sbjct: 1415 RHNAT--TNVYIHIEDVNDNAPQFEQQKYATTV--IEED---VDIPKVLFNVHATDADQD 1467
Query: 713 TGNVRFLIANQQDVTDDI-AIAE-DGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISG-A 768
+ R + + D++ I + GTI K LDR+ V + + +G
Sbjct: 1468 EKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLV 1527
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSK-IGTEIKMDNIIKATDADEGT--NALF 825
G V + + D NDN P+F + G+I EN + I ++ ++A D D+ T NA
Sbjct: 1528 GYADVQVNVRDINDNSPIFPERLF-GYIEENREPIHSDGVYFMDVQARDFDDPTTENANI 1586
Query: 826 MYTLFGE----GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
Y + G+ +F +D+NTG + F SLDRE +SSE E II
Sbjct: 1587 EYGIVRNKLINGESVFRIDQNTGKI-FAMRSLDRE----------------ISSEREFII 1629
Query: 882 MIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
+ ND + N +++ T +N A F K ++ V+
Sbjct: 1630 EVR-ANDRGVPSREGFANVTIKV---TDMNDNAPFF-----EKTRYEGSVE--------- 1671
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQI-RYEFNSE---VYIPPSKLSADALEVKRYFVINER 997
E PIG ++ +A D D + Y+ + E Y+ K + K+ V R
Sbjct: 1672 ETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDK------DSKQSSVGVLR 1725
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFP-VFKKTWYNFNVEE 1056
+ + F L I DG + + +V V + D NDH P + T + +
Sbjct: 1726 VKQPLDYEDVTQRDGFHLGIRVSDGRH-DAEAAVHVALVDRNDHAPHIHGATEHRVREDV 1784
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ T +G+ ATD D G A Q SD F I G L V LDRE Y
Sbjct: 1785 PRGTS--IGRYTATDRDAGDTARFRINRQ-SDPKRQFTIDQ-DGTLRVAHTLDREDIAVY 1840
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
L + A DN DVNDN P+ Y
Sbjct: 1841 NLIIEAYDN---SNNIGRQMVAVYLQDVNDNGPEPY 1873
Score = 89.4 bits (212), Expect = 7e-16
Identities = 118/476 (24%), Positives = 192/476 (40%), Gaps = 41/476 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV---GTVIGKVKAVDPD--LGQNG 493
L+ + +V+V + D NDN+P+F P L+ + ++ + G V+A D D +N
Sbjct: 1526 LVGYADVQVNVRDINDNSPIF-PERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENA 1584
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPANPSERRY 550
+ Y + R + S F+I+ NTG + S I R + ++ PS R
Sbjct: 1585 NIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPS--RE 1642
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ---NDVS 607
A VTI+VT + P F YE V IG +V DA E+ N +
Sbjct: 1643 GFANVTIKVT----DMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFT 1698
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
Y L E + ++ + V L R +P+ D+E V ++ +L I + H
Sbjct: 1699 YQLSE--ESDYFYVTTDKDSKQSSVGVL-RVKQPL-DYEDVTQRDGFHLGIRVSDGRHDA 1754
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV-RFLIANQQDV 726
+ ++ + H+P I E+ + + + G+ RF I Q D
Sbjct: 1755 EAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDP 1814
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
I +DGT+ LDRE VY + + A N I G V +Y++D NDN P
Sbjct: 1815 KRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNI---GRQMVAVYLQDVNDNGPE 1871
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEG---------TNALFMYTLFGEGKEMF 837
EN+ + + I+ATD D + F Y+ +
Sbjct: 1872 PYTVPRPCIFRENTPVNQLGTCE--IRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNA 1929
Query: 838 DVDENTGVVKFIG-DSLDREKKI---MYKLSLVARDTGGLSSEAELIIMIGDENDN 889
+ D G + DRE + + ++ L+ D G +EA + ++IGD NDN
Sbjct: 1930 NGDGGNGSMTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVIIGDLNDN 1985
Score = 88.2 bits (209), Expect = 2e-15
Identities = 178/758 (23%), Positives = 306/758 (40%), Gaps = 93/758 (12%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + + ND + VF+P++ Y + +A+ GT + +++A D D + D
Sbjct: 727 LSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMD 786
Query: 499 LQRTSNLTITSPFKINPNTGT------VSVAESPILEGRHALFVEASDQPA---NPSERR 549
S + + F I+ +TG VS A+ E L V D + PS+
Sbjct: 787 KNGRSTQKM-NLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTH 845
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPY----EFWVGSNVGIGTSVGQIRV--NDAFEQ 603
S A + I + NKP+ PD A Y + G+ ++ ++ +D+
Sbjct: 846 TSYATLLIGI-EDVNNNKPEFPDC--AKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSAN 902
Query: 604 NDVSYDLLHGYEEG-VPFAVEERSGVITVVDDL--SRYNRPMYDFEAVALQENANLSI-V 659
D+ Y L + E F ++ ++GV+T + R RP D A I
Sbjct: 903 GDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGF 962
Query: 660 TNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF-HTNMSSIYGNGTGNVRF 718
+V VVD+ND + ++ + + + G ++ +F N ++ T ++
Sbjct: 963 CQFSVEVVDINDNSPQFERPSYETSVSRFE--AVGTSVITVFAFDNDAAHNAEITYSLEI 1020
Query: 719 LIANQQDVTDDIAIAE-----DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
++ +D+ E G I KP+ K + VIA+ N + QV
Sbjct: 1021 DTTAGEEHQNDLDFFELVNRRSGEITLIKPIPM-KTQKFIFNVIADDNGIPEALQSSAQV 1079
Query: 774 TIYIEDENDNPPVFEHA--TYEGF-IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
T+ + D+ P ++ + G + EN ++ I + + D+ ++ ++ T
Sbjct: 1080 TLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDS-RNSDVIYKLTAS 1138
Query: 831 G------EGK-EMFDVDENTG--VVKFIGDSLDREKKIMYKLSLVARD-TGGLSSEAELI 880
G E K F+ EN V I + LD E+ Y L+L A D T ++S +
Sbjct: 1139 GGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKTFV 1198
Query: 881 IMIGDENDNKPEF------NQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQL 934
+ + D ND P+F I+E H E K NG I+ VK A+D D
Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLE-KTNGK---PIVTVK-----AIDTDSD 1249
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
GP + I + +D L G+I F +E + D ++ Y +
Sbjct: 1250 GPQNEVHYRIVGEANGEETKHFRIDE-LTGEI---FPNEKF--------DREKIDMYILT 1297
Query: 995 NERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
E + A LP +G N DN+ V++ + DVND+ P F++ Y V
Sbjct: 1298 VEASDRSVSA--LP----------GANGPN-KDNVKVQIVINDVNDNAPSFEEQKYIGRV 1344
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+E++ + + A D D +++NL Y I +PF + +G + V LD E
Sbjct: 1345 KESEGEGHDVITIKAHDLD--KHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEAS 1402
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D+Y L ++A D DVNDN+P+F
Sbjct: 1403 DQYHLVLIASDG----RHNATTNVYIHIEDVNDNAPQF 1436
Score = 81.4 bits (192), Expect = 2e-13
Identities = 125/485 (25%), Positives = 204/485 (42%), Gaps = 53/485 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V++ + D NDN P F Y +K + G + +KA D D N + Y L
Sbjct: 1319 VKVQIVINDVNDNAPSFEEQK-YIGRVKESEGEGHDVITIKAHDLDKHSN--LRYHLIGA 1375
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVT 560
I PF + ++GT+ V E E ++ L + ASD N + Y + IE
Sbjct: 1376 GGGRI--PFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDGRHNATTNVY----IHIEDV 1429
Query: 561 RGTKGNKPDIPDFMGAPYEFWV-GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE-EGV 618
+ P F Y V +V I + + DA +Q++ S +++ E +G
Sbjct: 1430 ND------NAPQFEQQKYATTVIEEDVDIPKVLFNVHATDA-DQDEKSSRIVYRLEGQGA 1482
Query: 619 P--FAVEERSGVITVVDDLSR---YNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
F + + SG I +V L R P ++F A+ ++ N L + V+V D+ND
Sbjct: 1483 DEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDN 1542
Query: 673 RGVLLKGAHSPIIFHVKENSAGA-AIGQIFHTNMSSIYGNGT---GNVRFLIANQQDVTD 728
+ + + +++EN + G F + + + T N+ + I + +
Sbjct: 1543 SPIFPER----LFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLING 1598
Query: 729 DIAIAED---GTIFTQKPLDREKRDVYRMTVIAEFN-KGVISGAGIYQVTIYIEDENDNP 784
+ D G IF + LDRE + N +GV S G VTI + D NDN
Sbjct: 1599 ESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNA 1658
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMF---DVD 840
P FE YEG + E + IG + A DAD E + +F Y L E + D D
Sbjct: 1659 PFFEKTRYEGSVEETAPIGAAVMS---FSAFDADEEAKDNVFTYQLSEESDYFYVTTDKD 1715
Query: 841 ---ENTGVVKFIGDSLDRE---KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
+ GV++ + LD E ++ + L + D G +EA + + + D ND+ P +
Sbjct: 1716 SKQSSVGVLR-VKQPLDYEDVTQRDGFHLGIRVSD-GRHDAEAAVHVALVDRNDHAPHIH 1773
Query: 895 QIEEN 899
E+
Sbjct: 1774 GATEH 1778
Score = 71.7 bits (168), Expect = 1e-10
Identities = 83/333 (24%), Positives = 141/333 (42%), Gaps = 28/333 (8%)
Query: 44 VDSDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYH 103
V +DS VK L + + LV I + + +A +V ++IEDVNDN P F Y
Sbjct: 1384 VRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNATTNVYIHIEDVNDNAPQFEQQKYA 1442
Query: 104 VTVDEL---------------TPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFD 148
TV E EK+ + G + + + ++A D
Sbjct: 1443 TTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALD 1502
Query: 149 RDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKR- 207
RD P S ++ + + +DDG+ + + V + R + D E + +
Sbjct: 1503 RDPPAGVPS-WNFVVQAIDDDGNGLVGYADVQVNV-RDINDNSPIFPERLFGYIEENREP 1560
Query: 208 IHKEILFPEPIHAIDQD--LGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLD 262
IH + ++ + A D D A + Y ++ N +F +D G +F + LD +
Sbjct: 1561 IHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDRE 1620
Query: 263 AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG 322
+ F+++V+A+ P + A V I++ D+NDN P FE Y S+ E P G
Sbjct: 1621 ISSERE---FIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIG 1677
Query: 323 FSVLQVMATDKD-QGENGEFTYQLDDPKGAFSI 354
+V+ A D D + ++ FTYQL + F +
Sbjct: 1678 AAVMSFSAFDADEEAKDNVFTYQLSEESDYFYV 1710
Score = 58.8 bits (136), Expect = 1e-06
Identities = 43/149 (28%), Positives = 76/149 (51%), Gaps = 10/149 (6%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
++ K F +D G + L + LD D + + L+V A + N + + + I + D
Sbjct: 580 DETKWFRIDPSTGIIHLTRLLDFDDPALPKLHK--LKVTAREDN---RESHVDLTIRIDD 634
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
+NDN+P F Y + E++P ++L+V A DKD G+N TY +D+ FSI+ +
Sbjct: 635 VNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHN--FSIN-SN 691
Query: 359 GWLTVRNQTVLDR--EAHSSLRMKVYAKE 385
G ++ + + D+ E H R V A++
Sbjct: 692 GEISAKVRLDADQLNERHFVYRFNVTARD 720
Score = 58.4 bits (135), Expect = 1e-06
Identities = 137/631 (21%), Positives = 236/631 (37%), Gaps = 67/631 (10%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ-NGMVLYDLQRT 502
NV + + D NDN P F ++ + + V+ V A D D + + ++Y L+
Sbjct: 1421 NVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQ 1480
Query: 503 SNLTITSPFKINPNTGTVSVAES-----PILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ F+I +GT+ + ++ P V+A D N A V +
Sbjct: 1481 GADEV---FRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGL---VGYADVQV 1534
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND----AFEQNDVSYDLLHG 613
V R N P P+ + E G ++ D E ++ Y ++
Sbjct: 1535 NV-RDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRN 1593
Query: 614 Y---EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI---VTNATVHVV 667
E V F +++ +G I + L R +F + + N T+ V
Sbjct: 1594 KLINGESV-FRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVT 1652
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV-RFLIANQQD- 725
D+ND K + + A F + + NV + ++ + D
Sbjct: 1653 DMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEA-----KDNVFTYQLSEESDY 1707
Query: 726 ---VTD-DIAIAEDGTIFTQKPLDRE---KRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
TD D + G + ++PLD E +RD + + + + A V + +
Sbjct: 1708 FYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAA----VHVALV 1763
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
D ND+ P AT E + E+ GT I ATD D G A F + K F
Sbjct: 1764 DRNDHAPHIHGAT-EHRVREDVPRGTSIGR---YTATDRDAGDTARFRINRQSDPKRQFT 1819
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEE 898
+D++ G ++ + +LDRE +Y L + A D + + + D NDN PE +
Sbjct: 1820 IDQD-GTLR-VAHTLDREDIAVYNLIIEAYDNSNNIGRQMVAVYLQDVNDNGPEPYTVPR 1877
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNAL-- 956
R + GT E++ ++ D + GP F + E P LN +
Sbjct: 1878 PCIFRENTPVNQLGTC-----EIRATDR---DTAEFGPPFTM-EVSPSFKYSQYLNVIFN 1928
Query: 957 DLDSGLNGQIR----YEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVA---RSLPP 1009
G NG + EF+ E +P L + R NE HVI+ +
Sbjct: 1929 ANGDGGNGSMTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVIIGDLNDNTMH 1988
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVND 1040
+ +++++ G L + + RV+V D +D
Sbjct: 1989 DGRMTIHVNSY-LGRLKETVIGRVYVDDADD 2018
Score = 54.8 bits (126), Expect = 2e-05
Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 5/131 (3%)
Query: 218 IHAIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D + Y L RK F +D G L + D E + + +
Sbjct: 892 VEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPRED---VT 948
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ + + +E++D+NDN P+FE Y S+ G SV+ V A D D
Sbjct: 949 VKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDA 1008
Query: 336 GENGEFTYQLD 346
N E TY L+
Sbjct: 1009 AHNAEITYSLE 1019
Score = 54.0 bits (124), Expect = 3e-05
Identities = 89/395 (22%), Positives = 160/395 (40%), Gaps = 55/395 (13%)
Query: 1014 RLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD 1073
+L ++A + N ++ + + + DVND+ P F + Y V E + + KV A D D
Sbjct: 612 KLKVTARED-NRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKD 670
Query: 1074 FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
G N+ +TY + + + ++ + ++ + E Y V ARD+G
Sbjct: 671 TGDNSRITYSVDNHNFSINSN-GEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSS 729
Query: 1134 XXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD---ELSNHNFESVMMIPVYKATIEENA 1190
+ ND S F + + +A + V + +++N
Sbjct: 730 SAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNG 789
Query: 1191 PIGTTVAKVFAND--TDFIGNGNGLILYSLPQRKNQQNLGL-----------PSLSST-- 1235
T +F+ D T + +G+ L + +N NL + PS + T
Sbjct: 790 R-STQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSY 848
Query: 1236 AILMVTVADVPDEVEMSDKPVF--ISRYYEL-EIEENV--NAPVELVSLNLTEHYENFKM 1290
A L++ + DV ++KP F ++Y ++ +I E P +V + T+ +
Sbjct: 849 ATLLIGIEDV-----NNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANG 903
Query: 1291 R-YYILNENDTDIRRTFVIDPRNGTLYLVRSP----DREVKDTYEVIVRAERQKYSRELP 1345
Y L ++ R+ FVID + G L SP DRE + +V V+A +
Sbjct: 904 DIVYSLYYTQSESRKAFVIDRQTGV--LTPSPHVVFDRETRPREDVTVKATDR------- 954
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ L G ++ V+VV D+NDNSP+F
Sbjct: 955 ------GDRPLIGFCQFSVEVV----DINDNSPQF 979
Score = 52.4 bits (120), Expect = 9e-05
Identities = 51/155 (32%), Positives = 80/155 (51%), Gaps = 17/155 (10%)
Query: 224 DLGVGATLRYELI-SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
DL + LRY LI +G R F + + +G++F+++ LD +A ++ + L + AS
Sbjct: 1361 DLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEA-----SDQYHLVLIASDGR 1415
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL-QVMATDKDQGE-NGE 340
+ A V I + D+NDN P+FE Y +++E + VL V ATD DQ E +
Sbjct: 1416 H---NATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSR 1472
Query: 341 FTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDRE 372
Y+L+ +GA F I SG T+ LDR+
Sbjct: 1473 IVYRLEG-QGADEVFRIGKYSG--TIELVKALDRD 1504
Score = 50.4 bits (115), Expect = 4e-04
Identities = 59/222 (26%), Positives = 93/222 (41%), Gaps = 19/222 (8%)
Query: 243 LFSLDSVNGSLFLEKEL---DLDAEHNLQANTFVLQVQASQLNNPLKT--AQARVEIELL 297
LFS+D G + L + DL N T ++Q S P KT + A + I +
Sbjct: 797 LFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIE 856
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGF------SVLQVMATDKDQGENGEFTYQL----DD 347
D+N+N PEF D S + + G ++++V ATD D NG+ Y L +
Sbjct: 857 DVNNNKPEFP-DCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSE 915
Query: 348 PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFADSQRIAKWRRQ 406
+ AF ID ++G LT V DRE + V A + + ++G S +
Sbjct: 916 SRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDN 975
Query: 407 PLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
+ P +T+ + VGT + +D N E+T
Sbjct: 976 SPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAH--NAEIT 1015
Score = 49.2 bits (112), Expect = 9e-04
Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 247 DSVNGSL-FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
DS S+ L + LD E Q + F L ++ S + A+A V + L+D ND+ P
Sbjct: 1715 DSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHD---AEAAVHVALVDRNDHAPH 1771
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY-QLDDPKGAFSIDPRSGWLTVR 364
+ + E++P G S+ + ATD+D G+ F + DPK F+ID + G T+R
Sbjct: 1772 IHGATEH-RVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTID-QDG--TLR 1827
Query: 365 NQTVLDRE--AHSSLRMKVYAKETN 387
LDRE A +L ++ Y N
Sbjct: 1828 VAHTLDREDIAVYNLIIEAYDNSNN 1852
Score = 48.4 bits (110), Expect = 0.002
Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 25/183 (13%)
Query: 218 IHAIDQDL-GVGATLRYELI---SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ AID D G + Y ++ +G + K F +D + G +F ++ D + + + ++
Sbjct: 1241 VKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDRE-----KIDMYI 1295
Query: 274 LQVQASQ--------LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
L V+AS N P K +V+I + D+NDN P FE Y + E+ G V
Sbjct: 1296 LTVEASDRSVSALPGANGPNKD-NVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDV 1354
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
+ + A D D+ N Y L G F + SG + V+ LD EA + +
Sbjct: 1355 ITIKAHDLDKHSN--LRYHLIGAGGGRIPFGVRTDSGTIFVKEP--LDFEASDQYHLVLI 1410
Query: 383 AKE 385
A +
Sbjct: 1411 ASD 1413
Score = 44.4 bits (100), Expect = 0.024
Identities = 56/249 (22%), Positives = 108/249 (43%), Gaps = 16/249 (6%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS-SIYGNGTGNVRFLIAN 722
+HV D+++ + + P++ V N IG+I + ++ +G+G NV + +
Sbjct: 411 IHVADIDEPPSFV--NSPLPMLAVVPLNPT---IGRIVYQFVARDEHGDGDSNVLYKTID 465
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDEN 781
I + G + T E+ D YR++ A + + + + + +V I +
Sbjct: 466 VIPAGSFIVDPKSGVVRTGWS-KYERGDTYRISAQAMDLSPSDNTTSQLSEVAILEILAD 524
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG-TNALFMYTLFGEGKE----M 836
+ PP F YE + E++ + + ++G + Y+L G+ E
Sbjct: 525 ERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKW 584
Query: 837 FDVDENTGVVKF--IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
F +D +TG++ + D D ++KL + AR+ S +L I I D NDN P F
Sbjct: 585 FRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNR-ESHVDLTIRIDDVNDNVPTFT 643
Query: 895 QIEENSKVR 903
+ ++VR
Sbjct: 644 RPLYTAQVR 652
Score = 44.0 bits (99), Expect = 0.032
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 18/157 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D+D G + + Y + + N FS++S NG + + LD D + N + + V
Sbjct: 664 VTAVDKDTGDNSRITYSVDNHN----FSINS-NGEISAKVRLDAD-QLNERHFVYRFNVT 717
Query: 278 ASQLNNPLK-TAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A P+ ++ A + I + ND F Y + E+ G V+Q+ A D D+
Sbjct: 718 ARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADR 777
Query: 336 GENGEFTYQLDDPKG-------AFSIDPRSGWLTVRN 365
E TY D G FSID +G + +R+
Sbjct: 778 ---DEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRH 811
Score = 44.0 bits (99), Expect = 0.032
Identities = 85/361 (23%), Positives = 139/361 (38%), Gaps = 35/361 (9%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP--SLTIPLTVPRGL 138
+ V + I DVNDN P F + Y V E G + +L L G
Sbjct: 1319 VKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGG 1378
Query: 139 TIFKDIRA-----FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY--D 191
I +R F ++ + SD ++ ++ +D H A + + + + V D
Sbjct: 1379 RIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDGRHNATTNVY---IHIEDVNDNAPQ 1435
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGAT-LRYELISGNDRKLFSLDSVN 250
+++ ++ I K +LF +HA D D ++ + Y L ++F + +
Sbjct: 1436 FEQQKYATTVIEEDVDIPK-VLFN--VHATDADQDEKSSRIVYRLEGQGADEVFRIGKYS 1492
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G++ L K LD D + + FV+Q N A V++ + D+NDN P F
Sbjct: 1493 GTIELVKALDRDPPAGVPSWNFVVQAIDDDGNG--LVGYADVQVNVRDINDNSPIFPERL 1550
Query: 311 YNISIVENL----PNGFSVLQVMATDKDQ--GENGEFTY-----QLDDPKGAFSIDPRSG 359
+ I EN +G + V A D D EN Y +L + + F ID +G
Sbjct: 1551 FGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTG 1609
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAP-LEKTT 418
+ LDRE S + + + V + K + NAP EKT
Sbjct: 1610 KIFAMRS--LDREISSEREFIIEVRANDRGVPSREGFANVTIK--VTDMNDNAPFFEKTR 1665
Query: 419 Y 419
Y
Sbjct: 1666 Y 1666
Score = 40.7 bits (91), Expect = 0.30
Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFV-PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
D L+ F V ++D NDN+P F PS YE S+ VGT + V A D D N
Sbjct: 956 DRPLIGFCQFSVEVVDINDNSPQFERPS--YETSVSRFEAVGTSVITVFAFDNDAAHNAE 1013
Query: 495 VLYDLQ 500
+ Y L+
Sbjct: 1014 ITYSLE 1019
Score = 37.9 bits (84), Expect = 2.1
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 17/117 (14%)
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
EN + Y I+ + F ID G ++ +RS DRE+ E I+ E + R +P
Sbjct: 1582 ENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFII--EVRANDRGVP 1639
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVM 1402
EG V +++ D+NDN+P F ++ TAP G VM
Sbjct: 1640 SR---------EGFAN----VTIKVTDMNDNAPFFEKTR--YEGSVEETAPIGAAVM 1681
Score = 35.9 bits (79), Expect = 8.6
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL-------- 319
Q N + L + A+ + + + + + V +E+ D+ND +P+F VD + +I E +
Sbjct: 1174 QVNNYTLTLTATDMTSRVASTKTFV-VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEK 1232
Query: 320 PNGFSVLQVMATDKD-QGENGEFTYQL 345
NG ++ V A D D G E Y++
Sbjct: 1233 TNGKPIVTVKAIDTDSDGPQNEVHYRI 1259
>UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix
metalloproteinase 13; n=8; Theria|Rep: PREDICTED: similar
to matrix metalloproteinase 13 - Monodelphis domestica
Length = 860
Score = 104 bits (249), Expect = 2e-20
Identities = 123/496 (24%), Positives = 199/496 (40%), Gaps = 58/496 (11%)
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
GP+ IPE+ P+G+ +A DLD GLNG Y ++ Y R+
Sbjct: 149 GPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANAYFHLH---------TRFRSH 199
Query: 995 NERHGHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWY 1050
++ +++ + L E + + L ++A+DGG+ + + + V DVND+ P F + Y
Sbjct: 200 GPKYAELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVY 259
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGEL 1108
+ E ++ V ATD D G N + Y + P F I+ G + + G +
Sbjct: 260 RAQILENSPNGSLVTSVSATDLDEGTNREIVYSLAQNPEGILQTFHINFENGEIRLRGPV 319
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK--FYAFDELLEWKHPEAD 1166
D E + Y + V A D G DVNDN+P + + P
Sbjct: 320 DFEAIENYDIDVQAIDGG---GLSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNT 376
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG----NGLILYSLPQRK 1222
++ + K T + T+ + F N + G + Y+L
Sbjct: 377 VVALFGVRDRDIRVGGKITCFIQGDLPFTIKQTFRNSYSLVTGGTLDREKVAGYNL--TI 434
Query: 1223 NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT 1282
+ G P LSS I+ V ++D+ D + PVF Y + + EN N+P +
Sbjct: 435 VAMDSGTPRLSSETIIEVVISDIND-----NPPVFKEASYTMTVREN-NSPAVFIGKVQA 488
Query: 1283 EHY---ENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
E EN ++ Y +L D + I+ NG LY +RS D E ++ +V+A
Sbjct: 489 EDLDSEENAQITYSLLPPESGDLSVFSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVN 548
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP----KFTNGNRPLVTAIPT 1393
P P++ ++ V+VVV DVNDN P N P +P
Sbjct: 549 GG-----P---LPLSSQII-------VRVVV--LDVNDNLPMILYPLQNSTSPCNDLVPR 591
Query: 1394 TAPFGYQVMQLKGAIG 1409
A GY V ++ G
Sbjct: 592 VAEVGYLVTKVVAVDG 607
Score = 84.6 bits (200), Expect = 2e-14
Identities = 111/471 (23%), Positives = 193/471 (40%), Gaps = 36/471 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+E L SF EV + D NDN P+F P++ + + +G+ A D D+G NG+
Sbjct: 123 EEPLQSF-RAEVRVFDINDNAPMF-PNHGPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQ 180
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSL 552
Y L + + + F+ + V P+ + + L + A D + +
Sbjct: 181 NYTLSANAYFHLHTRFRSHGPKYAELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQI 240
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
+V ++V ++P F Y + N G+ V + D E ++ Y L
Sbjct: 241 LIVVLDVN-------DNVPQFSRLVYRAQILENSPNGSLVTSVSATDLDEGTNREIVYSL 293
Query: 611 LHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
EG+ F + +G I + + YD + A+ + LS + V V+D
Sbjct: 294 AQN-PEGILQTFHINFENGEIRLRGPVDFEAIENYDIDVQAI-DGGGLSAHSKVLVEVMD 351
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
VND +L + I + E+S + +F I G + I T
Sbjct: 352 VNDNAPDVLI---TSISNRIPEDSPLNTVVALFGVRDRDIRVGG--KITCFIQGDLPFTI 406
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++ T LDREK Y +T++A + G + + + I D NDNPPVF+
Sbjct: 407 KQTFRNSYSLVTGGTLDREKVAGYNLTIVA-MDSGTPRLSSETIIEVVISDINDNPPVFK 465
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEM-----FDVDEN 842
A+Y + EN+ I ++A D D NA Y+L E ++ ++ N
Sbjct: 466 EASYTMTVRENNSPAVFI---GKVQAEDLDSEENAQITYSLLPPESGDLSVFSYISINSN 522
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELI--IMIGDENDNKP 891
G + + S+D E ++ + A + G L +++I +++ D NDN P
Sbjct: 523 NGKL-YALRSMDYEAIQAFQFVVKAVNGGPLPLSSQIIVRVVVLDVNDNLP 572
Score = 81.0 bits (191), Expect = 2e-13
Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 8/154 (5%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
KPLDRE++ +T+ A + G + +G Q+ I + D NDN P F Y I+ENS
Sbjct: 210 KPLDREEQPQVCLTLTA-VDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQILENSP 268
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFG--EG-KEMFDVDENTGVVKFIGDSLDREKK 858
G+ + + ATD DEGTN +Y+L EG + F ++ G ++ G +D E
Sbjct: 269 NGSLVTS---VSATDLDEGTNREIVYSLAQNPEGILQTFHINFENGEIRLRGP-VDFEAI 324
Query: 859 IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
Y + + A D GGLS+ +++++ + D NDN P+
Sbjct: 325 ENYDIDVQAIDGGGLSAHSKVLVEVMDVNDNAPD 358
Score = 68.9 bits (161), Expect = 1e-09
Identities = 56/170 (32%), Positives = 82/170 (48%), Gaps = 11/170 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKEL--DLDAEHNLQANTFVLQVQ 277
A D D+G+ Y L + L + +G + E L LD E Q L +
Sbjct: 169 AQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPKYAELVLIKPLDREEQPQV---CLTLT 225
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P K+ A++ I +LD+NDN+P+F Y I+EN PNG V V ATD D+G
Sbjct: 226 AVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQILENSPNGSLVTSVSATDLDEGT 285
Query: 338 NGEFTYQL-DDPKG---AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
N E Y L +P+G F I+ +G + +R +D EA + + V A
Sbjct: 286 NREIVYSLAQNPEGILQTFHINFENGEIRLRGP--VDFEAIENYDIDVQA 333
Score = 62.5 bits (145), Expect = 9e-08
Identities = 61/198 (30%), Positives = 89/198 (44%), Gaps = 20/198 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN I K+ A DLDS N QI Y +PP S D L V Y IN +G
Sbjct: 473 VRENNSPAVFIGKVQAEDLDSEENAQITYSL-----LPPE--SGD-LSVFSYISINSNNG 524
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFN-- 1053
+ RS+ E+ F+ + A++GG L + I VRV V DVND+ P+ N
Sbjct: 525 KLYALRSMDYEAIQAFQFVVKAVNGGPLPLSSQIIVRVVVLDVNDNLPMILYPLQNSTSP 584
Query: 1054 ----VEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGEL 1108
V ++ KV A D D GQN+ L+Y ++ +D L F + +G + +
Sbjct: 585 CNDLVPRVAEVGYLVTKVVAVDGDSGQNSWLSYELLKATDLGL-FSVGRQSGEIRTLRLI 643
Query: 1109 DRETEDKYILTVVARDNG 1126
K + + RD+G
Sbjct: 644 SERDSMKQKMVIAVRDHG 661
Score = 58.4 bits (135), Expect = 1e-06
Identities = 80/305 (26%), Positives = 134/305 (43%), Gaps = 30/305 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP----IGPSLTIPL 132
+SA+ V V + DVNDN P L T + E +P +F + +G +T +
Sbjct: 339 LSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNTVVALFGVRDRDIRVGGKITCFI 398
Query: 133 TVPRGLTIFKDIR-AFDRDKPNTPNSD--VHYSI-VSGNDDGHFALESSHKPVLLLRKVL 188
TI + R ++ T + + Y++ + D G L S +++ +
Sbjct: 399 QGDLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTIVAMDSGTPRLSSETIIEVVISDIN 458
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELI--SGNDRKLFS- 245
D KE + + + +F + A D D A + Y L+ D +FS
Sbjct: 459 DNPPVFKEASYTMTV--RENNSPAVFIGKVQAEDLDSEENAQITYSLLPPESGDLSVFSY 516
Query: 246 --LDSVNGSLFLEKELDLDAEHNLQANTFVLQ-VQASQLNNPLKTAQARVEIELLDLNDN 302
++S NG L+ + +D +A +QA FV++ V L PL ++Q V + +LD+NDN
Sbjct: 517 ISINSNNGKLYALRSMDYEA---IQAFQFVVKAVNGGPL--PL-SSQIIVRVVVLDVNDN 570
Query: 303 LPEFEVDFYNISIVEN--LPN----GFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI 354
LP N + N +P G+ V +V+A D D G+N +Y+L G FS+
Sbjct: 571 LPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNSWLSYELLKATDLGLFSV 630
Query: 355 DPRSG 359
+SG
Sbjct: 631 GRQSG 635
Score = 52.0 bits (119), Expect = 1e-04
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 9/173 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G +F ++ LDRE+ + F + ++ + + D NDN P+F +
Sbjct: 94 GDLFVKEKLDREELCGKADPCVLRFEIVLEEPLQSFRAEVRVFDINDNAPMFPNHGPVLK 153
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGD 851
I E++ +G+ + + A D D G N L YTL + K+ +
Sbjct: 154 IPESTPLGSRFPLQS---AQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPKYAELVLIK 210
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
LDRE++ L+L A D G S A+++I++ D NDN P+F+++ +++
Sbjct: 211 PLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQI 263
Score = 46.0 bits (104), Expect = 0.008
Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
L+S + ++ F L G LF++++LD + E +A+ VL+ + L PL++ +A E+
Sbjct: 78 LVSDDSKQHFRLHRKTGDLFVKEKLDRE-ELCGKADPCVLRFEIV-LEEPLQSFRA--EV 133
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ D+NDN P F + I E+ P G A D D G NG Y L
Sbjct: 134 RVFDINDNAPMFPNHGPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTL 184
Score = 41.5 bits (93), Expect = 0.17
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN-----AKVGTVIGKVKAVDPDLGQNG 493
L S + V V +LD NDN P+ + S ++ A+VG ++ KV AVD D GQN
Sbjct: 554 LSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNS 613
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVS-VAESPILEGRHALFVEASDQPA 543
+ Y+L + ++L + S + + T+ ++E ++ + + V QP+
Sbjct: 614 WLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPS 664
Score = 39.9 bits (89), Expect = 0.53
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 11/172 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + Y L + L F ++ NG + L +D +A N + +
Sbjct: 276 VSATDLDEGTNREIVYSLAQNPEGILQTFHINFENGEIRLRGPVDFEAIEN-----YDID 330
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
VQA ++ +A ++V +E++D+NDN P+ + + I E+ P V D+D
Sbjct: 331 VQA--IDGGGLSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNTVVALFGVRDRDI 388
Query: 336 GENGEFT-YQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
G+ T + D R+ + V T LDRE + + + A ++
Sbjct: 389 RVGGKITCFIQGDLPFTIKQTFRNSYSLVTGGT-LDREKVAGYNLTIVAMDS 439
Score = 35.9 bits (79), Expect = 8.6
Identities = 15/42 (35%), Positives = 26/42 (61%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE 108
+V + +G ++S+ + V I D+NDN P+F + Y +TV E
Sbjct: 434 IVAMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRE 475
>UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB26D2 UniRef100
entry - Canis familiaris
Length = 599
Score = 104 bits (249), Expect = 2e-20
Identities = 135/485 (27%), Positives = 201/485 (41%), Gaps = 40/485 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V VE+ + D ND++P F P + + + GT + A DPD G G Y
Sbjct: 128 LGAVVQVEIRVNDVNDHSPRF-PRDSLRLDVSELSPPGTAVRLPGAHDPDAGLFGTQGYT 186
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASD--QPANPSERRYSLAV 554
L L +P P + + E H L +EA D +P R L V
Sbjct: 187 LL-LFQLRYGTPGSSPPEPLDLVLLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRV 245
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHG 613
+ + + P P F Y V + G V ++R D +N + L
Sbjct: 246 LD-------ENDNP--PVFERGEYRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRA 296
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDE 672
+ PFAVEE SGV+ V L R + + A A + T +V V+DVND
Sbjct: 297 RQ--APFAVEELSGVVRVRRPLDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDN 354
Query: 673 RGVLLKGAHSPIIFH--VKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
+ H ++ S GAA G + ++S G+ + +
Sbjct: 355 PPAI----HLLLLTDGGAARVSEGAAPGDYVARVSVSDADGDPEPRDSLSLEGGEGAFAL 410
Query: 730 IAIAEDGTIF--TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
A G F PLDRE RD+Y + ++A + G + + + + D ND PPVF
Sbjct: 411 RAGGSPGVFFLCVAGPLDREARDLYDLRLVAT-DAGSPPLSAEETLLLRVADLNDRPPVF 469
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADE-GT-NALFMYTLF---GEGKEMFDVDEN 842
Y G + E + GT + + ATDADE GT +A Y L G F +D
Sbjct: 470 GRERYVGSVSEAAAPGTAVLR---VSATDADEAGTDHARLRYALVHLPGRCAPAFAIDPE 526
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENS 900
+GV+ SLDRE + +L +VA+D G LS+ + I + D NDN+P F + N+
Sbjct: 527 SGVIS-TSRSLDREVQEAVELRVVAQDLGAPPLSATCLVSITVDDVNDNEPVFRRQVYNA 585
Query: 901 KVRIH 905
+ H
Sbjct: 586 TLAEH 590
Score = 103 bits (248), Expect = 3e-20
Identities = 103/370 (27%), Positives = 158/370 (42%), Gaps = 23/370 (6%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ VE+ +LD NDN PVF Y +++ +A G + +V+A D DLG+NG+V Y L+
Sbjct: 239 LRVELRVLDENDNPPVFERGE-YRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRAR 297
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVT 560
+PF + +G V V E + H L VEA D A P L+V ++V
Sbjct: 298 Q-----APFAVEELSGVVRVRRPLDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVN 352
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVP 619
+ GA V G V ++ V+DA + L L G E
Sbjct: 353 DNPPAIHLLLLTDGGAAR---VSEGAAPGDYVARVSVSDADGDPEPRDSLSLEGGEGAFA 409
Query: 620 FAVEERSGV--ITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVL 676
GV + V L R R +YD VA + LS + V D+ND V
Sbjct: 410 LRAGGSPGVFFLCVAGPLDREARDLYDLRLVATDAGSPPLSAEETLLLRVADLNDRPPVF 469
Query: 677 LKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD-VTDDIAI-A 733
+ V E +A G A+ ++ T+ G +R+ + + AI
Sbjct: 470 ---GRERYVGSVSEAAAPGTAVLRVSATDADEA-GTDHARLRYALVHLPGRCAPAFAIDP 525
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G I T + LDRE ++ + V+A+ + G + V+I ++D NDN PVF Y
Sbjct: 526 ESGVISTSRSLDREVQEAVELRVVAQ-DLGAPPLSATCLVSITVDDVNDNEPVFRRQVYN 584
Query: 794 GFIMENSKIG 803
+ E++ +G
Sbjct: 585 ATLAEHAPVG 594
Score = 73.3 bits (172), Expect = 5e-11
Identities = 42/112 (37%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L ++A P +T RVE+ +LD NDN P FE Y ++ E+ P G V +V ATD+
Sbjct: 223 LHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCRVRATDR 282
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G NG Y L + F+++ SG + VR LDREA + ++ V A++
Sbjct: 283 DLGRNGLVRYSLRARQAPFAVEELSGVVRVRRP--LDREAQAWHQLLVEARD 332
Score = 66.9 bits (156), Expect = 4e-09
Identities = 47/140 (33%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L+I A DGG ++ V + V D ND+ PVF++ Y V E + +V ATD
Sbjct: 223 LHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCRVRATDR 282
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
D G+N + Y ++ PF + L+GV+ V LDRE + + L V ARD G
Sbjct: 283 DLGRNGLVRYSLRARQA--PFAVEELSGVVRVRRPLDREAQAWHQLLVEARDGG-APPEV 339
Query: 1133 XXXXXXXXXXDVNDNSPKFY 1152
DVNDN P +
Sbjct: 340 ATVRLSVAVLDVNDNPPAIH 359
Score = 62.1 bits (144), Expect = 1e-07
Identities = 49/145 (33%), Positives = 69/145 (47%), Gaps = 7/145 (4%)
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L + A D G+ L+ ++ + V D+ND PVF + Y +V EA + +V AT
Sbjct: 435 YDLRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSAT 494
Query: 1071 DADFG--QNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
DAD +A L Y + P F I P +GV+S + LDRE ++ L VVA+D G
Sbjct: 495 DADEAGTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQEAVELRVVAQDLG 554
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 555 -APPLSATCLVSITVDDVNDNEPVF 578
Score = 56.4 bits (130), Expect = 6e-06
Identities = 90/353 (25%), Positives = 134/353 (37%), Gaps = 41/353 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P G + ++ A D D G NG +RY + + F + E G
Sbjct: 264 VREDAPPGAEVCRVRATDRDLGRNGLVRYSLRAR---------------QAPFAVEELSG 308
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVR--VFVKDVNDHFPVFKKTWYN---- 1051
V V R L E++ +L + A DGG + +VR V V DVND+ P
Sbjct: 309 VVRVRRPLDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGA 368
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV--LSVNGELD 1109
V E + +V +DAD + ++ + GV L V G LD
Sbjct: 369 ARVSEGAAPGDYVARVSVSDADGDPEPRDSLSLEGGEGAFALRAGGSPGVFFLCVAGPLD 428
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF---YAFDELLEWKHPEAD 1166
RE D Y L +VA D G D+ND P F + E P
Sbjct: 429 REARDLYDLRLVATDAG-SPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTA 487
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGL---ILYSLPQR 1221
L ++ + + A FA D + I L + ++ R
Sbjct: 488 VLRVSATDADEAGTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQEAVELR 547
Query: 1222 KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV 1274
Q+LG P LS+T ++ +TV DV D ++PVF + Y + E +APV
Sbjct: 548 VVAQDLGAPPLSATCLVSITVDDVND-----NEPVFRRQVYNATLAE--HAPV 593
Score = 53.6 bits (123), Expect = 4e-05
Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 8/118 (6%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L++ A+ +P +A+ + + + DLND P F + Y S+ E G +VL+V ATD
Sbjct: 437 LRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATDA 496
Query: 334 DQG--ENGEFTYQLDDPKG----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+ ++ Y L G AF+IDP SG + LDRE ++ ++V A++
Sbjct: 497 DEAGTDHARLRYALVHLPGRCAPAFAIDPESG--VISTSRSLDREVQEAVELRVVAQD 552
Score = 51.6 bits (118), Expect = 2e-04
Identities = 56/190 (29%), Positives = 83/190 (43%), Gaps = 19/190 (10%)
Query: 721 ANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
++ + DD + A+ G I T + LDRE+RD Y F + GA + QV I + D
Sbjct: 88 SDDSPLLDDFHVHADTGIIRTARRLDRERRDRY------GFAAATLLGA-VVQVEIRVND 140
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKE 835
ND+ P F + + E S GT +++ A D D G YTL G
Sbjct: 141 VNDHSPRFPRDSLRLDVSELSPPGTAVRLPG---AHDPDAGLFGTQGYTLLLFQLRYGTP 197
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
E +V + LDRE ++L + A D G + + + + DENDN P F
Sbjct: 198 GSSPPEPLDLV--LLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVF 255
Query: 894 NQIEENSKVR 903
+ E + VR
Sbjct: 256 ERGEYRAAVR 265
Score = 48.0 bits (109), Expect = 0.002
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 229 ATLRYELIS--GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
A LRY L+ G F++D +G + + LD + + ++ L+V A L P
Sbjct: 504 ARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQEAVE-----LRVVAQDLGAPPL 558
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+A V I + D+NDN P F YN ++ E+ P G LQ
Sbjct: 559 SATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVGHCFLQ 599
Score = 46.4 bits (105), Expect = 0.006
Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 17/176 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+DLG +RY L + + F+++ ++G + + + LD +A+ Q L V+
Sbjct: 277 VRATDRDLGRNGLVRYSLRAR--QAPFAVEELSGVVRVRRPLDREAQAWHQ-----LLVE 329
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEV----DFYNISIVENLPNGFSVLQVMATDK 333
A P + A R+ + +LD+NDN P + D + E G V +V +D
Sbjct: 330 ARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVSDA 389
Query: 334 DQGENGEFTYQLDDPKGAFSI----DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D + L+ +GAF++ P +L V LDREA +++ A +
Sbjct: 390 DGDPEPRDSLSLEGGEGAFALRAGGSPGVFFLCVAGP--LDREARDLYDLRLVATD 443
Score = 41.1 bits (92), Expect = 0.23
Identities = 21/44 (47%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 1440 QATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARDA 1483
+ATD D+G N +RY + QAP FA++ +SG VRV L R+A
Sbjct: 278 RATDRDLGRNGLVRYSLRARQAP-FAVEELSGVVRVRRPLDREA 320
Score = 38.3 bits (85), Expect = 1.6
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 31/181 (17%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P LS+ L++ VAD+ D PVF Y + E ++ ++ T+ E
Sbjct: 445 GSPPLSAEETLLLRVADLNDR-----PPVFGRERYVGSVSEAAAPGTAVLRVSATDADEA 499
Query: 1287 ---NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRE 1343
+ ++RY +++ F IDP +G + RS DREV++ E+ V
Sbjct: 500 GTDHARLRYALVHLPGR-CAPAFAIDPESGVISTSRSLDREVQEAVELRV---------- 548
Query: 1344 LPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTA-IPTTAPFGYQVM 1402
VA+D+ V + + DVNDN P F R + A + AP G+ +
Sbjct: 549 -------VAQDLGAPPLSATCLVSITVDDVNDNEPVF---RRQVYNATLAEHAPVGHCFL 598
Query: 1403 Q 1403
Q
Sbjct: 599 Q 599
Score = 36.3 bits (80), Expect = 6.5
Identities = 16/41 (39%), Positives = 24/41 (58%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G +SA V++ ++DVNDN P+F Y+ T+ E P G
Sbjct: 554 GAPPLSATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVG 594
>UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-PA -
Drosophila melanogaster (Fruit fly)
Length = 2002
Score = 103 bits (247), Expect = 4e-20
Identities = 125/479 (26%), Positives = 212/479 (44%), Gaps = 46/479 (9%)
Query: 445 VEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+ + +LD NDNNP F +P Y S+ N+ G +I V A D D +N + Y L+
Sbjct: 987 LSIQVLDENDNNPKFRLP--FYRQSITENSINGAMIVNVLASDVD--KNRTITYALE--G 1040
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
N T S ++P TG + VA S I +H + + R SL V I V
Sbjct: 1041 NPTYRSLMHLDPQTGEIVVA-SKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDEN 1099
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN--DVSYDLLHGYEEGVPFA 621
N P F+G + + N GT V ++ DA + +++ L+ F
Sbjct: 1100 DNN----PYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGKITF-LMDRISSQGKFT 1154
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--------VHVVDVNDER 673
++ +GV+TV D L R ++ Y+ + +N + + + ++D ND
Sbjct: 1155 IDADTGVLTVADRLDRESKDSYNL-VIEAWDNYQFGFLAGESRNAFKQVFISILDENDNP 1213
Query: 674 GVLLKGAHSPII--FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ +I +H + +G+ + NG + N+ + +
Sbjct: 1214 PEVDLPMSCVLITEYHELHERVASIVGKDADDPTTP---NGRLDFAITRGNKDGMFELRQ 1270
Query: 732 I-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
I A + IF K L R + Y +T+ + G+ + + I + D ND+ PVF
Sbjct: 1271 IDAWNAQIFASKSL-RNRYGNYSLTITTR-DMGLPANIVHNTLDICVSDFNDHAPVFVRP 1328
Query: 791 TYEGFIM--ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE---GKEMFDVDENTGV 845
+ + EN+ +GT I A+D D G NAL Y L + +MF+VD +TG
Sbjct: 1329 LHNTTVRIPENATVGTLILQ---AYASDGDMGQNALVRYRLKPDPLGSYKMFEVDGSTGE 1385
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEF--NQIEEN 899
+ F+ + L+REK+ ++++ + A D G LSS+ +L I + + ND +P+F N+I N
Sbjct: 1386 L-FLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVNEISVN 1443
Score = 99.5 bits (237), Expect = 6e-19
Identities = 175/754 (23%), Positives = 296/754 (39%), Gaps = 93/754 (12%)
Query: 215 PEPIHAIDQDLG--VGATLRYELISGNDRKLFSLDSVNG------SLFLEKELDLDAEHN 266
P + A D DL + + YE++ G R F++D +G S E+ +D + +
Sbjct: 640 PLQLEARDADLNGTENSQVTYEIVEGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRS 699
Query: 267 -------LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL 319
L V+A P+ + V I + D+NDN P F+ FY ++ E+L
Sbjct: 700 DPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTVPEDL 759
Query: 320 PNGFSVLQVMATDKD-QGENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSL 377
P G SVLQV A D+D N Y++ G F I+ +G ++V + LD + S
Sbjct: 760 PGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESK 819
Query: 378 RMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDE 437
R +Y S F RI K P P +G +
Sbjct: 820 R-SLYTLSVVRSKEIPFC---RILK----PFRNCLP----QIALDGGLG---------NS 858
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QLM+ V +++ D N+ PV + + N VGT++ +++A D D ++ Y
Sbjct: 859 QLMTTCTVNISIQDVNNKPPVL--KEMPALQILENTPVGTLVYRIQATDLD--HKAILRY 914
Query: 498 DLQ--------------RTSNLTITSPFKINPNTGTVSVAESPILEG-RHALFVEASDQP 542
L ++S F+++ GT+ V + E H +
Sbjct: 915 KLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDL 974
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
A R+ + ++I+V N P F Y + N G + + +D +
Sbjct: 975 AAAKGRQIAEGFLSIQVLDENDNN----PKFRLPFYRQSITENSINGAMIVNVLASDVDK 1030
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANL-SIVTN 661
++Y L ++ ++G I V + +F A S + +
Sbjct: 1031 NRTITYALEGNPTYRSLMHLDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVD 1090
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFL- 719
+ V+D ND + G+ + + + EN+A G + + + S G + FL
Sbjct: 1091 VYITVLDENDNNPYFVGGSKN---YTISENAAPGTRVATLQAGDADS---GDFGKITFLM 1144
Query: 720 --IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGA---GIYQ 772
I++Q T D A+ G + LDRE +D Y + + A + G ++G Q
Sbjct: 1145 DRISSQGKFTID---ADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRNAFKQ 1201
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLF 830
V I I DENDNPP + I E ++ + I DAD+ T N + +
Sbjct: 1202 VFISILDENDNPPEVDLPMSCVLITEYHELHERVAS---IVGKDADDPTTPNGRLDFAIT 1258
Query: 831 GEGKE-MFDVDE-NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS--EAELIIMIGDE 886
K+ MF++ + + + R + Y L++ RD G ++ L I + D
Sbjct: 1259 RGNKDGMFELRQIDAWNAQIFASKSLRNRYGNYSLTITTRDMGLPANIVHNTLDICVSDF 1318
Query: 887 NDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIE 920
ND+ P F + N+ VRI N T G I++
Sbjct: 1319 NDHAPVFVRPLHNTTVRIPE----NATVGTLILQ 1348
Score = 94.7 bits (225), Expect = 2e-17
Identities = 229/976 (23%), Positives = 377/976 (38%), Gaps = 149/976 (15%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D D P FV + +A VGT + +V+A+D D G N + Y L+ ++L
Sbjct: 269 VKVKDLEDQPPEFVEVQAVA-RIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLE-ANDL- 325
Query: 507 ITSPFKINPNTGTVSVA-------ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
F INP+TG V +S + G H L + A++ + S + + V EV
Sbjct: 326 ----FDINPHTGIVHTLTKLDREEQSDQVNGAHILRISATE--LSKSNTQMAPTTVRTEV 379
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR------VNDAFEQNDVSYDLL-- 611
T +IP F Y V N T + I V D E N+ ++ L
Sbjct: 380 TVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFRLFLD 439
Query: 612 --HGYEEGVP-FAVEERSGVITVVD----DLSRYNRPMYDFEAVALQENANLSIVTNATV 664
+ E VP AV E + ++ V + D ++ + A + E + S + +
Sbjct: 440 PPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSA-HVQI 498
Query: 665 HVVDVNDE----------RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTG 714
+ D ND VL II HV+ + + M Y N G
Sbjct: 499 FIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGD----YGTMGIRYTNLRG 554
Query: 715 NVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
+ L+ N +T I I + GT F DRE + +TV A N G Q+
Sbjct: 555 GIAHLL-NLNPITGVITIKQAGGTAF-----DREIISRHYLTVEAIDNAGQ-GNRNTAQI 607
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGT-NALFMYTLF- 830
+ I D NDN P F YE ++EN E + ++A DAD GT N+ Y +
Sbjct: 608 IVDILDVNDNAPTFPQRQYETKLLENQ---AEFETPLQLEARDADLNGTENSQVTYEIVE 664
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNK 890
G + F +D +G+++ + S D E+ + TGG S E+ +++ +
Sbjct: 665 GLYRSNFTIDPQSGLLRPV-HSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGI 723
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
P + + +I V+ N A Q +PE++P G+++
Sbjct: 724 PMLSTVVP------------------VLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSV 765
Query: 951 IKLNALDLD-SGLNGQIRYE----------FNSEVYI----PPSKLSADALEVKR--YFV 993
+++ A+D D S N + Y NSE + + L D E KR Y +
Sbjct: 766 LQVTAIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTL 825
Query: 994 INERHGHVIVARSLPPESEFRLNISALDGGNLNDNI----SVRVFVKDVNDHFPVFKKTW 1049
R + R L P I ALDGG N + +V + ++DVN+ PV K+
Sbjct: 826 SVVRSKEIPFCRILKPFRNCLPQI-ALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKE-M 883
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP---------------SDTDL--P 1092
+ E ++ ++ ATD D A L Y + P S+ D
Sbjct: 884 PALQILENTPVGTLVYRIQATDLD--HKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGA 941
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
FE+ + G L V LDRE + L + D D NDN+PKF
Sbjct: 942 FEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKF 1001
Query: 1152 YAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA--KVFANDTDFIGN 1209
L ++ ++ ++ M++ V + +++N I + + +
Sbjct: 1002 ----RLPFYR----QSITENSINGAMIVNVLASDVDKNRTITYALEGNPTYRSLMHLDPQ 1053
Query: 1210 GNGLILYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
+++ S + Q L G+P+ SS + +TV D E + P F+
Sbjct: 1054 TGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLD-----ENDNNPYFVGG 1108
Query: 1261 YYELEIEENVNAPVELVSLNLTE-HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVR 1319
I EN + +L + +F ++++ + + F ID G L +
Sbjct: 1109 SKNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISS--QGKFTIDADTGVLTVAD 1166
Query: 1320 SPDREVKDTYEVIVRA 1335
DRE KD+Y +++ A
Sbjct: 1167 RLDRESKDSYNLVIEA 1182
Score = 84.2 bits (199), Expect = 2e-14
Identities = 112/481 (23%), Positives = 193/481 (40%), Gaps = 43/481 (8%)
Query: 451 DANDNNPVFVPSNLYEFSMK-SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITS 509
D NDN P F+P Y+ +++ V+ ++A D D G G V+Y LQ
Sbjct: 164 DINDNVPTFLP---YQNAIEIPEGSAPGVVSTLEATDADEGAYGQVVYYLQELDGDNDVF 220
Query: 510 PFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
+ G + + + E + + L V A D+ AN A + ++V K +
Sbjct: 221 SIATHQGKGILRLQKELDYERKSLYQLRVLAIDR-ANQGPINTGTAAILVKV----KDLE 275
Query: 568 PDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
P+F+ + + +GT V ++R D ++ + + E F + +G
Sbjct: 276 DQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDG--DRGINNPIAYSLEANDLFDINPHTG 333
Query: 628 VITVVDDLSRYNRP-------MYDFEAVALQEN----ANLSIVTNATVHVVDVNDERGVL 676
++ + L R + + A L ++ A ++ T TV V DVNDE
Sbjct: 334 IVHTLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTF 393
Query: 677 LKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGN---VRFLIANQQD---VTDD 729
+ + V EN+ + I + ++ + GN R + D + +
Sbjct: 394 GETVYR---CEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPE 450
Query: 730 IAIAEDG---TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+A+ E + K LD E+ T+ A S V I+I D+NDN P
Sbjct: 451 LAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAR-EVDEPSRWSSAHVQIFIRDQNDNFPE 509
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
F Y ++ENS+ T I + D GT + L G + +++ TGV+
Sbjct: 510 FSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVI 569
Query: 847 KFI---GDSLDREKKIMYKLSLVARDTGGLSSE--AELIIMIGDENDNKPEFNQIEENSK 901
G + DRE + L++ A D G + A++I+ I D NDN P F Q + +K
Sbjct: 570 TIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETK 629
Query: 902 V 902
+
Sbjct: 630 L 630
Score = 70.5 bits (165), Expect = 3e-10
Identities = 187/879 (21%), Positives = 347/879 (39%), Gaps = 95/879 (10%)
Query: 41 DSLVDSDSPQNVVKFRLGCDFDEGDDLVRI-GAGLNQISAYLSVTVYIEDVNDNVPIFLD 99
+ LVD S ++ E D LVR +G+ +S + V +Y++DVNDN PIF
Sbjct: 689 EELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQ 748
Query: 100 TPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDV 159
+ Y TV E P G + A DRD + PN+ V
Sbjct: 749 SFYAKTVPEDLPGGSSVL-------------------------QVTAIDRD-GSAPNNVV 782
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKV-LDYDAGDKE---FQLVIMASGKRIHKEIL-- 213
Y I +G D F + S + + LD D + + + L ++ S + IL
Sbjct: 783 VYRIQTGAGD-KFIINSETGVISVAHGANLDPDLTESKRSLYTLSVVRSKEIPFCRILKP 841
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD-LDAEHNLQANTF 272
F + I D G+G + + N S+ VN + KE+ L N T
Sbjct: 842 FRNCLPQIALDGGLGNSQLMTTCTVN----ISIQDVNNKPPVLKEMPALQILENTPVGTL 897
Query: 273 VLQVQASQLNNP--LKTAQARVEIE-LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
V ++QA+ L++ L+ E + + E DF V+++ V++++
Sbjct: 898 VYRIQATDLDHKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLL 957
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
D+++ E+ + ++D A G+L++ Q + + + + R+ Y + +
Sbjct: 958 --DRERVEHIKLAITVEDLAAAKGRQIAEGFLSI--QVLDENDNNPKFRLPFYRQSITEN 1013
Query: 390 ------VVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVG--TKTENIEYYDEQLMS 441
+V A + LE N ++ P + G I++ Q ++
Sbjct: 1014 SINGAMIVNVLASDVDKNRTITYALEGNPTYRSLMHLDP-QTGEIVVASKIDHEQHQWLN 1072
Query: 442 F--------VNVEVTLLDA-------NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
F + +L+D NDNNP FV + +++ NA GT + ++A D
Sbjct: 1073 FSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGS-KNYTISENAAPGTRVATLQAGD 1131
Query: 487 PDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQ--- 541
D G G + + + R S+ F I+ +TG ++VA+ E + + L +EA D
Sbjct: 1132 ADSGDFGKITFLMDRISS---QGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQF 1188
Query: 542 PANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDA 600
E R + V I + N P++ M + + + + VG+ +
Sbjct: 1189 GFLAGESRNAFKQVFISIL-DENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPT 1247
Query: 601 FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNR-PMYDFEAVALQENANLSIV 659
+ + + G ++G+ + + + S NR Y +IV
Sbjct: 1248 TPNGRLDFAITRGNKDGMFELRQIDAWNAQIFASKSLRNRYGNYSLTITTRDMGLPANIV 1307
Query: 660 TNA-TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
N + V D ND V ++ H+ + + + G I Q + ++ + N R
Sbjct: 1308 HNTLDICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASD-GDMGQNALVRYRL 1366
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTIYI 777
G +F ++ L+REK+ ++ + + A +++G+ S + +TIY+
Sbjct: 1367 KPDPLGSYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEA-YDQGLPTSLSSDLDLTIYV 1425
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTE-IKM-DNI----IKATDADEGTNALFMYTLFG 831
+ ND P F E+S G+E IK+ D I ++ D ++ + + + + G
Sbjct: 1426 RNVNDYEPQFMVNEISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNG 1485
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
F +D T ++ + LDRE ++ +L R T
Sbjct: 1486 NEAGYFRLDPETHILT-VDRELDRE--VIANFTLYVRAT 1521
Score = 66.9 bits (156), Expect = 4e-09
Identities = 63/260 (24%), Positives = 117/260 (45%), Gaps = 30/260 (11%)
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V D+ND L ++ + E SA + + T+ G V + +
Sbjct: 162 VEDINDNVPTFLPYQNA---IEIPEGSAPGVVSTLEATDADE---GAYGQVVYYLQELDG 215
Query: 726 VTDDIAIAED---GTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDE 780
D +IA G + QK LD E++ +Y++ V+A N+G I+ G + + ++D
Sbjct: 216 DNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPIN-TGTAAILVKVKDL 274
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
D PP F I E++ +GT++ ++A D D G N Y+L E ++FD++
Sbjct: 275 EDQPPEFVEVQAVARIAEDAPVGTKVLR---VRAIDGDRGINNPIAYSL--EANDLFDIN 329
Query: 841 ENTGVVKFIGDSLDREKKI-----MYKLSLVARDTGGLSSE-------AELIIMIGDEND 888
+TG+V + LDRE++ + L + A + +++ E+ +++ D ND
Sbjct: 330 PHTGIVHTL-TKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVND 388
Query: 889 NKPEFNQIEENSKVRIHRET 908
P F + +V + +T
Sbjct: 389 EIPTFGETVYRCEVNENAQT 408
Score = 66.9 bits (156), Expect = 4e-09
Identities = 134/535 (25%), Positives = 217/535 (40%), Gaps = 107/535 (20%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S +V++ + D NDN P F +Y S+ N++ T+I V+AVD D G G +
Sbjct: 492 SSAHVQIFIRDQNDNFPEF-SQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGI--- 547
Query: 501 RTSNLT--ITSPFKINPNTGTVSVAES------PILEGRHALFVEASDQPANPSERRYSL 552
R +NL I +NP TG +++ ++ + RH L VEA D N + +
Sbjct: 548 RYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAID---NAGQGNRNT 604
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA----FEQNDVSY 608
A + +++ N P P YE + N + Q+ DA E + V+Y
Sbjct: 605 AQIIVDIL-DVNDNAPTFPQ---RQYETKLLENQAEFETPLQLEARDADLNGTENSQVTY 660
Query: 609 DLLHGYEEGVPFAVEERSGVI---------TVVDDLSRYNRP----MYDFEAVALQENAN 655
+++ G F ++ +SG++ +VD SR + P + + L A
Sbjct: 661 EIVEGLYRS-NFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRAR 719
Query: 656 ------LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI-------FH 702
LS V ++V DVND + + ++ + ++ G+++ Q+
Sbjct: 720 DSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTV--PEDLPGGSSVLQVTAIDRDGSA 777
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE--- 759
N +Y TG I N + T I++A + L KR +Y ++V+
Sbjct: 778 PNNVVVYRIQTGAGDKFIINSE--TGVISVAHGANL--DPDLTESKRSLYTLSVVRSKEI 833
Query: 760 --------FNK-----GVISGAGIYQ------VTIYIEDENDNPPVFEHATYEGFIMENS 800
F + G G Q V I I+D N+ PPV + I+EN+
Sbjct: 834 PFCRILKPFRNCLPQIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMPALQ-ILENT 892
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE------------------MFDVDEN 842
+GT + I+ATD D A+ Y L E E F+VD
Sbjct: 893 PVGTLVYR---IQATDLDH--KAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSI 947
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDENDNKPEF 893
G +K + LDRE+ KL++ D G +E L I + DENDN P+F
Sbjct: 948 EGTLKVV-KLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKF 1001
Score = 66.1 bits (154), Expect = 7e-09
Identities = 54/162 (33%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
Query: 218 IHAIDQDLGV-GATLRYELISGNDRKLFSLDSVNGS--LFLEKELDLDAEHNLQANTFVL 274
+ A D D G G + Y D +FS+ + G L L+KELD + + Q +
Sbjct: 193 LEATDADEGAYGQVVYYLQELDGDNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAI 252
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-IVENLPNGFSVLQVMATDK 333
+A+Q P+ T A + +++ DL D PEF V+ ++ I E+ P G VL+V A D
Sbjct: 253 D-RANQ--GPINTGTAAILVKVKDLEDQPPEF-VEVQAVARIAEDAPVGTKVLRVRAIDG 308
Query: 334 DQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
D+G N Y L + F I+P +G V T LDRE S
Sbjct: 309 DRGINNPIAYSL-EANDLFDINPHTG--IVHTLTKLDREEQS 347
Score = 64.5 bits (150), Expect = 2e-08
Identities = 51/187 (27%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ AID D G+ + Y L ND LF ++ G + +LD + + + +L++
Sbjct: 303 VRAIDGDRGINNPIAYSL-EAND--LFDINPHTGIVHTLTKLDREEQSDQVNGAHILRIS 359
Query: 278 ASQL---NNPLKTAQARVEIELL--DLNDNLPEFEVDFYNISIVENL----PNGF--SVL 326
A++L N + R E+ ++ D+ND +P F Y + EN P F +
Sbjct: 360 ATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEV 419
Query: 327 QVMATDKDQGENGEFTYQLDDPKGAFSIDPR------SGWLTVRNQTVLDREAHSSLRMK 380
Q + D D+G NG F LD P F I P + L V+N LD E + +
Sbjct: 420 QNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFT 479
Query: 381 VYAKETN 387
++A+E +
Sbjct: 480 IFAREVD 486
Score = 62.1 bits (144), Expect = 1e-07
Identities = 48/172 (27%), Positives = 77/172 (44%), Gaps = 13/172 (7%)
Query: 222 DQDLGVGATLRYELISGNDR----KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
D D G T R L ND +++ N L ++ LD E + N +
Sbjct: 425 DHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIF--- 481
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +++ P + + A V+I + D NDN PEF YN S++EN + V A D D G+
Sbjct: 482 AREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGD 541
Query: 338 NGEFTYQLDDPKGA----FSIDPRSGWLTVRNQ--TVLDREAHSSLRMKVYA 383
G + + +G +++P +G +T++ T DRE S + V A
Sbjct: 542 YGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEA 593
Score = 61.7 bits (143), Expect = 2e-07
Identities = 101/414 (24%), Positives = 164/414 (39%), Gaps = 55/414 (13%)
Query: 994 INERHGHVIVARSLPPESEFRLNIS--ALDGG--NLNDNISVRVFVKDVNDHFPVFKKTW 1049
++ + G ++VA + E LN S A D G + + V + V D ND+ P F
Sbjct: 1050 LDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGS 1109
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
N+ + E + + A DAD G +T+ + + F I TGVL+V LD
Sbjct: 1110 KNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTGVLTVADRLD 1169
Query: 1110 RETEDKYILTVVARDNG-----XXXXXXXXXXXXXXXXDVNDNSPK---------FYAFD 1155
RE++D Y L + A DN D NDN P+ +
Sbjct: 1170 RESKDSYNLVIEAWDNYQFGFLAGESRNAFKQVFISILDENDNPPEVDLPMSCVLITEYH 1229
Query: 1156 ELLE----WKHPEADELSNHNFESVMMIP-VYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
EL E +AD+ + N I K + E I A++FA+ + G
Sbjct: 1230 ELHERVASIVGKDADDPTTPNGRLDFAITRGNKDGMFELRQIDAWNAQIFASKSLRNRYG 1289
Query: 1211 NGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV 1270
N YSL +++GLP+ L + V+D D PVF+ + +
Sbjct: 1290 N----YSL--TITTRDMGLPANIVHNTLDICVSDFNDHA-----PVFVRPLHNTTVRIPE 1338
Query: 1271 NAPVELVSLNL----TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
NA V + L + +N +RY L + + F +D G L+L +RE +
Sbjct: 1339 NATVGTLILQAYASDGDMGQNALVRYR-LKPDPLGSYKMFEVDGSTGELFLKEQLNREKQ 1397
Query: 1327 DTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+E+ + A Y + LP + D+ + + +++VND P+F
Sbjct: 1398 KIHEIRIEA----YDQGLPTSL------------SSDLDLTIYVRNVNDYEPQF 1435
Score = 60.9 bits (141), Expect = 3e-07
Identities = 67/271 (24%), Positives = 117/271 (43%), Gaps = 26/271 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S+ L +T+Y+ +VND P F+ V E + G + + +P
Sbjct: 1415 LSSDLDLTIYVRNVNDYEPQFMVNEISVNFTEHSDPGSER---------------IKLPD 1459
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
TI KD + D PN S V Y IV+GN+ G+F L+ +L + + LD +
Sbjct: 1460 --TIDKD--QLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETH-ILTVDRELDREV-IAN 1513
Query: 197 FQLVIMASGKRIHKEILFPEPIHAIDQDLG--VGATLRYELISGNDRKLFS--LDSVNGS 252
F L + A+ + I E + ++ +G + + G DR S L S +
Sbjct: 1514 FTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHNQQF-GYDRFKHSRQLRSTESN 1572
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
+ ++ +L + ++ + + L + +V++ +LD+NDN P F +
Sbjct: 1573 EYGPEDAELLSYEAYDSSQEDPTGGLATTHPELDSTVIKVKVRVLDINDNPPRFRSKIFT 1632
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
I N G ++V ATD D+G+NG Y
Sbjct: 1633 GGITTNADFGLKFMRVEATDADEGDNGRIGY 1663
Score = 58.8 bits (136), Expect = 1e-06
Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 24/199 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN +GT I++ A D D G N +RY +L D L + F ++ G
Sbjct: 1336 IPENATVGTLILQAYASDGDMGQNALVRY-----------RLKPDPLGSYKMFEVDGSTG 1384
Query: 1000 HVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTWYNFN- 1053
+ + L E + + I A D G +L+ ++ + ++V++VND+ P F + N
Sbjct: 1385 ELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVNEISVNF 1444
Query: 1054 VEEAQYTRRVLGKVDATDAD-------FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
E + + D D D + + YFI + F + P T +L+V+
Sbjct: 1445 TEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETHILTVDR 1504
Query: 1107 ELDRETEDKYILTVVARDN 1125
ELDRE + L V A +N
Sbjct: 1505 ELDREVIANFTLYVRATEN 1523
Score = 56.8 bits (131), Expect = 4e-06
Identities = 52/212 (24%), Positives = 98/212 (46%), Gaps = 12/212 (5%)
Query: 157 SDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFP 215
++V+++I + D S+H + + D + EF Q + AS ++
Sbjct: 474 TEVNFTIFAREVDEPSRWSSAHVQIF----IRDQNDNFPEFSQTIYNASVLENSEQDTII 529
Query: 216 EPIHAIDQDLGVGATL--RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A+D D G T+ RY + G L +L+ + G + +++ + + + +
Sbjct: 530 THVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHY- 588
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L V+A A++ +++LD+NDN P F Y ++EN + LQ+ A D
Sbjct: 589 LTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDA 648
Query: 334 DQG--ENGEFTYQLDDP--KGAFSIDPRSGWL 361
D EN + TY++ + + F+IDP+SG L
Sbjct: 649 DLNGTENSQVTYEIVEGLYRSNFTIDPQSGLL 680
Score = 56.0 bits (129), Expect = 7e-06
Identities = 91/408 (22%), Positives = 163/408 (39%), Gaps = 46/408 (11%)
Query: 1001 VIVARSLPPE--SEFRLNISALDGGNLNDNISVRVF---VKDVNDHFPVFKKTWYNFNVE 1055
+ +A+ L E E+ + ++ D + N + F V+D+ND+ P F +
Sbjct: 123 IFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIP 182
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISPL--TGVLSVNGELDRET 1112
E V+ ++ATDAD G + Y++Q D D F I+ G+L + ELD E
Sbjct: 183 EGS-APGVVSTLEATDADEGAYGQVVYYLQELDGDNDVFSIATHQGKGILRLQKELDYER 241
Query: 1113 EDKYILTVVARDNGXXX-XXXXXXXXXXXXXDVNDNSPKFYAFD-------------ELL 1158
+ Y L V+A D D+ D P+F ++L
Sbjct: 242 KSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVL 301
Query: 1159 EWKHPEADE-LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+ + D ++N S+ ++ I + I T+ K+ + NG ++ S
Sbjct: 302 RVRAIDGDRGINNPIAYSLEANDLF--DINPHTGIVHTLTKLDREEQSDQVNGAHILRIS 359
Query: 1218 LPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVE 1275
+ P+ T + ++ V+DV DE+ P F Y E+ EN N P+
Sbjct: 360 ATELSKSNTQMAPTTVRTEVTVI-VSDVNDEI-----PTFGETVYRCEVNENAQTNTPLN 413
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD-TYEVIVR 1334
+ E +N + +E + R F +DP N +V P+ V + + + V+
Sbjct: 414 FID----EEVQNVVFDH---DEGNNGTFRLF-LDPPNDLFEIV--PELAVNEANFMLRVK 463
Query: 1335 AERQKYSRELPHMIYPV-AEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
+ + + + + A +V E V + I+D NDN P+F+
Sbjct: 464 NSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFS 511
Score = 55.2 bits (127), Expect = 1e-05
Identities = 62/256 (24%), Positives = 109/256 (42%), Gaps = 20/256 (7%)
Query: 658 IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
I+ + +V N + G S I+ +KE S +G + +T Y +
Sbjct: 44 IILTTLISLVASNRPPRFAIDG-QSEIVLRLKE-SPETKVGTLIYTLKG--YDPDNDPLT 99
Query: 718 FLIANQQDVTDDIAIAEDG----TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
F N D ++ I I G IF K LDRE +D Y + + +
Sbjct: 100 FGKRNSHD-SEIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSF 158
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FG 831
+ +ED NDN P F Y+ I G+ + + ++ATDADEG +Y L
Sbjct: 159 LLLVEDINDNVPTF--LPYQNAI--EIPEGSAPGVVSTLEATDADEGAYGQVVYYLQELD 214
Query: 832 EGKEMFDVDENTGV-VKFIGDSLDREKKIMYKLSLVARDTGGL----SSEAELIIMIGDE 886
++F + + G + + LD E+K +Y+L ++A D + A +++ + D
Sbjct: 215 GDNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDL 274
Query: 887 NDNKPEFNQIEENSKV 902
D PEF +++ +++
Sbjct: 275 EDQPPEFVEVQAVARI 290
Score = 52.0 bits (119), Expect = 1e-04
Identities = 63/229 (27%), Positives = 100/229 (43%), Gaps = 19/229 (8%)
Query: 237 SGNDRKLFSLDSVNGS---LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVE 293
+ +D ++ +++ G+ +FL KELD + + VL + S ++ Q+ +
Sbjct: 104 NSHDSEIIRIENTGGNEAKIFLAKELDRELQDEY---AIVLTLTDSHYSDHNYVTQSFLL 160
Query: 294 IELLDLNDNLPEFEVDFYN-ISIVENLPNGFSVLQVMATDKDQGENGEFTY---QLDDPK 349
+ + D+NDN+P F + + N I I E G V + ATD D+G G+ Y +LD
Sbjct: 161 L-VEDINDNVPTF-LPYQNAIEIPEGSAPGV-VSTLEATDADEGAYGQVVYYLQELDGDN 217
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA---KETNPSVVGTFADSQRIAKWRRQ 406
FSI G +R Q LD E S +++V A P GT A ++ Q
Sbjct: 218 DVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQ 277
Query: 407 PLETNAPLEKTTYVFPD-KVGTKTENIEYYDEQLMSFVNVEVTLLDAND 454
P E ++ + D VGTK + D N L+AND
Sbjct: 278 PPEF-VEVQAVARIAEDAPVGTKVLRVRAIDGD-RGINNPIAYSLEAND 324
Score = 50.4 bits (115), Expect = 4e-04
Identities = 49/167 (29%), Positives = 71/167 (42%), Gaps = 21/167 (12%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+ +V + + D NDNPP F + G I N+ G + ++ATDADEG N Y
Sbjct: 1609 VIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMR---VEATDADEGDNGRIGYYQ 1665
Query: 830 FGE------------GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA 877
GE K F +D+ TG V+ D + K + ++A DT G+ A
Sbjct: 1666 VGEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDP-QKGMKGYFDFVVLANDTSGMKDVA 1724
Query: 878 ELIIMIGDENDNKPEF----NQIEENSKVRIHRETKLNGTAGFTIIE 920
+ I + E D K F E S+V R+T N T I+
Sbjct: 1725 HVFIYLLRE-DQKVRFVFRLQPDELRSRVDSFRDTLSNITESIVNID 1770
Score = 41.5 bits (93), Expect = 0.17
Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 19/178 (10%)
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN---VNAPVELVSLNLTEH-YENFK 1289
+TA ++V + DV D P F R YE ++ EN P++L + + + EN +
Sbjct: 603 NTAQIIVDILDVNDNA-----PTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQ 657
Query: 1290 MRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE--VKDTYEVIVRAERQKYS-RELPH 1346
+ Y I+ + R F IDP++G L V S D E V + +S RE+
Sbjct: 658 VTYEIV---EGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDL 714
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
++ A D M V V++ ++DVNDN+P F +P P G V+Q+
Sbjct: 715 LVR--ARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSF--YAKTVPEDLPGGSSVLQV 768
Score = 41.5 bits (93), Expect = 0.17
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 9/92 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY----D 498
+ V+V +LD NDN P F S ++ + +NA G +V+A D D G NG + Y +
Sbjct: 1610 IKVKVRVLDINDNPPRF-RSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQVGE 1668
Query: 499 LQRTSNLTI----TSPFKINPNTGTVSVAESP 526
+++T + + +PF ++ TG V + P
Sbjct: 1669 IRQTLSEGLENVRKAPFLLDQETGEVQLNFDP 1700
>UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16;
Theria|Rep: Protocadherin-12 precursor - Homo sapiens
(Human)
Length = 1184
Score = 103 bits (247), Expect = 4e-20
Identities = 127/545 (23%), Positives = 225/545 (41%), Gaps = 32/545 (5%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ ++VE+ +LD ND+ P F P E + +A + T I +A+DPD G N + Y L
Sbjct: 116 LALIHVEIQVLDINDHQPRF-PKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTL 174
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLAVVTI 557
+ + + + + + H+ F V + NP + SL V +
Sbjct: 175 SPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNV 234
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYE 615
+ + P F + + + GT + ++ D + +V + L
Sbjct: 235 ------LDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMP 288
Query: 616 EGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDE 672
V F+++ ++G + + L P Y+ + A N + + V+DVND
Sbjct: 289 PEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDN 348
Query: 673 -RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + A P + + + I + ++ S + NG + +L
Sbjct: 349 IPSIHVTWASQPSLVS-EALPKDSFIALVMADDLDSGH-NGLVHC-WLSQELGHFRLKRT 405
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ T LDRE+ Y +T++A+ ++G+ + Q++I I D NDN PVFE +
Sbjct: 406 NGNTYMLLTNATLDREQWPKYTLTLLAQ-DQGLQPLSAKKQLSIQISDINDNAPVFEKSR 464
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIG 850
YE EN+ + IKA DAD G N Y + + +D NTG V
Sbjct: 465 YEVSTRENNLPSLHL---ITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVT-AQ 520
Query: 851 DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ-IEENSKVRIHRE 907
SL+ E+ ++ ++A D+G L+S + + + D NDN PE Q + + K +
Sbjct: 521 RSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASL--S 578
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIR 967
+N + G ++ ++ N PL + TTI+ A D DSG NG+
Sbjct: 579 VLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIV---ARDADSGANGEPL 635
Query: 968 YEFNS 972
Y S
Sbjct: 636 YSIRS 640
Score = 89.8 bits (213), Expect = 5e-16
Identities = 117/426 (27%), Positives = 179/426 (42%), Gaps = 53/426 (12%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+E+G + T + LDRE+ + F+ + V I + D ND+ P F
Sbjct: 81 SEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQ 140
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
E I E++ + T I +D +A D D G N L YTL E F +D G
Sbjct: 141 ELEISESASLRTRIPLD---RALDPDTGPNTLHTYTL--SPSEHFALDVIVGP------- 188
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
D K +L +V + S +L++ D N N P+ S V+++ +
Sbjct: 189 -DETKHA--ELIVVKELDREIHSFFDLVLTAYD-NGNPPKSG----TSLVKVNVLDSNDN 240
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
+ F ++ AL++ E+ GT +IKL A D D G NG++ EF
Sbjct: 241 SPAFA------ESSLALEIQ---------EDAAPGTLLIKLTATDPDQGPNGEV--EFFL 283
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-GGN-LNDN 1028
++PP EV F I+ + G VI+ R L E + +++ A D G N + +
Sbjct: 284 SKHMPP--------EVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAH 335
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYN--FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
V + V DVND+ P TW + V EA + V A D D G N + ++
Sbjct: 336 CKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQ 395
Query: 1087 SDTDLPFE-ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ + T +L N LDRE KY LT++A+D G D+N
Sbjct: 396 ELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQG-LQPLSAKKQLSIQISDIN 454
Query: 1146 DNSPKF 1151
DN+P F
Sbjct: 455 DNAPVF 460
Score = 72.9 bits (171), Expect = 6e-11
Identities = 124/506 (24%), Positives = 205/506 (40%), Gaps = 66/506 (13%)
Query: 997 RHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
+H +IV + L E S F L ++A D GN + V+V V D ND+ P F ++
Sbjct: 192 KHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLAL 251
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELD 1109
++E +L K+ ATD D G N + +F+ P + F I TG + + LD
Sbjct: 252 EIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLD 311
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW-KHPE--AD 1166
E Y + V ARD G DVNDN P + + W P ++
Sbjct: 312 YEKNPAYEVDVQARDLG-PNPIPAHCKVLIKVLDVNDNIPSIH-----VTWASQPSLVSE 365
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG-LILYSLPQRKNQ- 1224
L +F +++M + N + +++ + NGN ++L + + Q
Sbjct: 366 ALPKDSFIALVMADDLDS--GHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQW 423
Query: 1225 ---------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
Q+ GL LS+ L + ++D+ D + PVF YE+ EN +
Sbjct: 424 PKYTLTLLAQDQGLQPLSAKKQLSIQISDIND-----NAPVFEKSRYEVSTRENNLPSLH 478
Query: 1276 LVSLNL--TEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
L+++ + N K+ Y I D+ + ID G + RS + E +E V
Sbjct: 479 LITIKAHDADLGINGKVSYRI---QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQV 535
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN---GNRPLVTA 1390
+AED + M V V V + D NDN+P+ + +
Sbjct: 536 -----------------IAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLS 578
Query: 1391 IPTTAPFGYQVMQLKGAIGHHPTASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINA 1450
+ A G+ ++ ++ G P + T T R L LT+ A D+D G N
Sbjct: 579 VLVNASTGHLLVPIETPNGLGPAGTDTPPLATHS----SRPFL--LTTIVARDADSGANG 632
Query: 1451 DIRYQILN-EQAPRFAIDPVSGTVRV 1475
+ Y I + +A F ++P +G + V
Sbjct: 633 EPLYSIRSGNEAHLFILNPHTGQLFV 658
Score = 64.9 bits (151), Expect = 2e-08
Identities = 129/540 (23%), Positives = 213/540 (39%), Gaps = 49/540 (9%)
Query: 31 HVSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIGA--GLNQISAYLSVTVYIE 88
H +I+ + +D + S + + G G LV++ + A+ ++ +E
Sbjct: 193 HAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALE 252
Query: 89 DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSL--TIPLTVPRGLTIFKDIRA 146
D P L T + P GE F FL + P + T + G I + R
Sbjct: 253 IQEDAAPGTLLIKLTATDPDQGPNGEVEF-FLSKHMPPEVLDTFSIDAKTGQVILR--RP 309
Query: 147 FDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGK 206
D +K P +V V D G + + H VL+ KVLD + V AS
Sbjct: 310 LDYEK--NPAYEVD---VQARDLGPNPIPA-HCKVLI--KVLDVNDNIPSIH-VTWASQP 360
Query: 207 RIHKEILFPEPIHAI--DQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDA 263
+ E L + A+ DL G + F L NG+ + L LD
Sbjct: 361 SLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDR 420
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
E T L Q L PL +A+ ++ I++ D+NDN P FE Y +S EN
Sbjct: 421 EQ-WPKYTLTLLAQDQGLQ-PL-SAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSL 477
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
++ + A D D G NG+ +Y++ D A +ID +G +T Q L+ E + +V
Sbjct: 478 HLITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTA--QRSLNYEEMAGFEFQV 535
Query: 382 YAKETNPSVVGTFADSQRIAKW-RRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLM 440
A+++ ++ + ++ W NAP E V D + + + L+
Sbjct: 536 IAEDSGQPML-----ASSVSVWVSLLDANDNAP-EVVQPVLSDGKASLSVLVNASTGHLL 589
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+ L A + P + F + T++ + D D G NG LY ++
Sbjct: 590 VPIETPNGLGPAGTDTPPLATHSSRPFLLT------TIVAR----DADSGANGEPLYSIR 639
Query: 501 RTSNLTITSPFKINPNTGT--VSVAESPILEGRH-ALFVEASDQPANPSERRYSLAVVTI 557
+ + F +NP+TG V+V + L G L + DQ + P + R L V+ +
Sbjct: 640 SGNEAHL---FILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFV 696
Score = 62.1 bits (144), Expect = 1e-07
Identities = 76/337 (22%), Positives = 145/337 (43%), Gaps = 37/337 (10%)
Query: 579 EFWVGSNVGIGTSVGQIRVNDAFE----QNDVSYDLLHGYEEGVPFAVEERSGVITVVDD 634
++ V V GT +G++ E Q ++ +L + +P V+ G+++
Sbjct: 33 KYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQ-LPQALPIQVDSEEGLLSTGRR 91
Query: 635 LSR------YNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV 688
L R ++ + F+ +A +L+++ + + V+D+ND + KG
Sbjct: 92 LDREQLCRQWDPCLVSFDVLA---TGDLALI-HVEIQVLDINDHQPRFPKGEQE------ 141
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIAIAEDGT----IFTQKP 743
E S A++ + + G + + ++ + D+ + D T + K
Sbjct: 142 LEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKE 201
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE + + V+ ++ G +G V + + D NDN P F ++ I E++ G
Sbjct: 202 LDREIHSFFDL-VLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPG 260
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDENTGVVKFIGDSLDREKKI 859
T + + ATD D+G N + L E + F +D TG V + LD EK
Sbjct: 261 TLLIK---LTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQV-ILRRPLDYEKNP 316
Query: 860 MYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
Y++ + ARD G + + +++I + D NDN P +
Sbjct: 317 AYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIH 353
Score = 40.3 bits (90), Expect = 0.40
Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 7/112 (6%)
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
A VEI++LD+ND+ P F + I E+ + A D D G N TY L
Sbjct: 117 ALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTL-S 175
Query: 348 PKGAFSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKET-NPSVVGT 393
P F++D G ++ + LDRE HS + + A + NP GT
Sbjct: 176 PSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGT 227
>UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep:
Cadherin-3 precursor - Caenorhabditis elegans
Length = 3343
Score = 103 bits (247), Expect = 4e-20
Identities = 83/278 (29%), Positives = 132/278 (47%), Gaps = 19/278 (6%)
Query: 622 VEERSGVITVVD--DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
+E+ +G++ D Y+ + A +N LS +T AT+ +VD+ND +
Sbjct: 1989 MEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQ 2048
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIF 739
+ F+V ENS IG + ++ + + V + I D + + E G I
Sbjct: 2049 LYR---FNVTENSGPKLIGHVIARDI-----DRSSRVFYEIVG-GDANHEFMVTESGQIE 2099
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
+ + LDRE + Y + ++ + G G V + + DE+DN P F + + E+
Sbjct: 2100 SVRDLDRETKSEYHL-IVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSR-IFHVEVPED 2157
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+IG + + A+DADE +N F GEG F VDENTG+V F+ DSLD EKK
Sbjct: 2158 VRIGEPVIQ---LSASDADEHSNHRFELDGGGEGIP-FRVDENTGMV-FVNDSLDFEKKQ 2212
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
Y++ + D G E L + + D NDN P F + E
Sbjct: 2213 SYRIKVKLTD-GAWLIETSLFVNVKDVNDNAPIFEKPE 2249
Score = 79.4 bits (187), Expect = 7e-13
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 11/175 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + Y ++SGN LF+++S G + + LD E +++ L ++A
Sbjct: 1676 AEDLDEGQNGLVTYSILSGNT-SLFAVNSTTGDIL--SLIPLDRE---ESSLHELLIEAK 1729
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P +A +++ I + D+NDN PEFE+ Y I I EN G +++++ATDKD+
Sbjct: 1730 DAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKDKDAEL 1789
Query: 340 EFTYQLDDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLR--MKVYAKETNPSVV 391
+++ + +D F I+ +GW+TV + ++RE + R +KV E + V+
Sbjct: 1790 QYSLESNDEITIPFRINVATGWITVAGK--VNREENEEFRFFVKVTDGEKSSKVI 1842
Score = 73.3 bits (172), Expect = 5e-11
Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 28/291 (9%)
Query: 434 YYDEQLMSFVN-VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
Y+D + +S + + ++D NDN+P F LY F++ N+ +IG V A D D ++
Sbjct: 2019 YFDNKPLSTITKATIKIVDINDNSPRF-DQQLYRFNVTENSGP-KLIGHVIARDID--RS 2074
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYS 551
V Y++ F + + SV + + + L VEA D P R +
Sbjct: 2075 SRVFYEIVGGD---ANHEFMVTESGQIESVRDLDRETKSEYHLIVEAIDD-GKPRRRGNT 2130
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL 611
+VT+ + P F + V +V IG V Q+ +DA E ++ ++L
Sbjct: 2131 TVIVTV------LDEDDNAPRFSRI-FHVEVPEDVRIGEPVIQLSASDADEHSNHRFEL- 2182
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G EG+PF V+E +G++ V D L + Y + V L + A L I T+ V+V DVND
Sbjct: 2183 DGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIK-VKLTDGAWL-IETSLFVNVKDVND 2240
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ K + +F +ENS A IGQ ++M S G +R+ + +
Sbjct: 2241 NAPIFEKPEY---LFISEENS--AEIGQFHASDMDS---ENNGKIRYSVTS 2283
Score = 71.7 bits (168), Expect = 1e-10
Identities = 81/300 (27%), Positives = 136/300 (45%), Gaps = 19/300 (6%)
Query: 616 EGVPFAVEERSGVITV--VDDLSRYNRPMYDFEAVALQE-NANLSIVTNATV-HVVDVND 671
EG F +++ T+ D N P+ DFE + N T+ + HV D ND
Sbjct: 1585 EGSVFRIQDNDYNFTISPFDGTIFTNSPL-DFENIKTYRFNITAGKSTSQVIIHVTDEND 1643
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDI 730
E + G + V E + I ++++ G G V + I + T
Sbjct: 1644 EAPRFITG--DVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGN--TSLF 1699
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
A+ + G I + PLDRE+ ++ + + A+ + G+ S + ++ I++ D NDN P FE
Sbjct: 1700 AVNSTTGDILSLIPLDREESSLHELLIEAK-DAGIPSLSATSKILIHVGDINDNTPEFEL 1758
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
++Y I ENSKIG++I I ATD D+ + E F ++ TG +
Sbjct: 1759 SSYFIKISENSKIGSKIIR---ILATDKDKDAELQYSLESNDEITIPFRINVATGWITVA 1815
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
G ++RE+ ++ + D G SS+ + I + D NDN P N + NS + + T+
Sbjct: 1816 G-KVNREENEEFRFFVKVTD-GEKSSKVIVEIHVEDFNDNHPMIN--DRNSDIFVPDPTR 1871
Score = 65.7 bits (153), Expect = 9e-09
Identities = 107/478 (22%), Positives = 194/478 (40%), Gaps = 58/478 (12%)
Query: 430 ENIEYYDEQLM---SFVNVEVTLLDANDNNPVFVPS---NLYEFSMKSNAKVGTVIGKVK 483
ENI+ Y + S V + + D ND P F+ NL +IG
Sbjct: 1616 ENIKTYRFNITAGKSTSQVIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSI 1675
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTV-SVAESPILEGR-HALFVEASDQ 541
A D D GQNG+V Y + + TS F +N TG + S+ E H L +EA D
Sbjct: 1676 AEDLDEGQNGLVTYSILSGN----TSLFAVNSTTGDILSLIPLDREESSLHELLIEAKDA 1731
Query: 542 PANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF 601
+ + ++ T P+F + Y + N IG+ + +I D
Sbjct: 1732 GIPSLSATSKILIHVGDINDNT-------PEFELSSYFIKISENSKIGSKIIRILATDKD 1784
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
+ ++ Y L E +PF + +G ITV ++R + F + ++
Sbjct: 1785 KDAELQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKVTDGEKSSKVIVE 1844
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLI 720
+HV D ND ++ +S I S +I H N+ + + + +++F +
Sbjct: 1845 --IHVEDFNDNH-PMINDRNSDIFVPDPTRSV-----EIIHVINVHDL--DKSDHLKFSL 1894
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
N ++ ++E+G I + PL + R+TV + +G + ++
Sbjct: 1895 NN-----SNLNLSENGEITLKSPL--QTAVPVRVTVSDD------AGHVAFMEYLFHPHS 1941
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD 840
+ PVF + E+ + E+ + KA + D Y++ + +++
Sbjct: 1942 RKHFPVFVEKLDTVSVREHDE--QELA---VFKA-NGDS-----IRYSIVSRCSDHLEME 1990
Query: 841 ENTGVVKFIGDSLDREKK---IMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
++TG++K SLD E+ +++ ++ D LS+ + I I D NDN P F+Q
Sbjct: 1991 KSTGILK-TKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQ 2047
Score = 63.7 bits (148), Expect = 4e-08
Identities = 76/273 (27%), Positives = 126/273 (46%), Gaps = 34/273 (12%)
Query: 837 FDVDENTG---VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGD-ENDNKPE 892
F+V EN+G + I +DR ++ Y++ + + +E+ I + D + + K E
Sbjct: 2052 FNVTENSGPKLIGHVIARDIDRSSRVFYEIVGGDANHEFMVTESGQIESVRDLDRETKSE 2111
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIK 952
++ I E + + + T I+ V ++ A ++ + +PE++ IG +I+
Sbjct: 2112 YHLIVE--AIDDGKPRRRGNTT--VIVTVLDEDDNAPRFSRIFHVE-VPEDVRIGEPVIQ 2166
Query: 953 LNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE 1012
L+A D D N + + E IP F ++E G V V SL E +
Sbjct: 2167 LSASDADEHSNHRFELDGGGEG-IP--------------FRVDENTGMVFVNDSLDFEKK 2211
Query: 1013 --FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+R+ + DG L + S+ V VKDVND+ P+F+K Y F EE +G+ A+
Sbjct: 2212 QSYRIKVKLTDGAWLIET-SLFVNVKDVNDNAPIFEKPEYLFISEE---NSAEIGQFHAS 2267
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
D D N + Y S T F+I P TGVLS
Sbjct: 2268 DMDSENNGKIRY----SVTSPYFKIEPSTGVLS 2296
Score = 63.3 bits (147), Expect = 5e-08
Identities = 96/362 (26%), Positives = 142/362 (39%), Gaps = 69/362 (19%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
DGTIFT PLD E YR + A G QV I++ DEND P F
Sbjct: 1604 DGTIFTNSPLDFENIKTYRFNITA--------GKSTSQVIIHVTDENDEAPRFITGDVVN 1655
Query: 795 F--IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ E + + + + I A D DEG N L Y++ +F V+ T GD
Sbjct: 1656 LKVLEELDTVSYPLIIGSSI-AEDLDEGQNGLVTYSILSGNTSLFAVNSTT------GDI 1708
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
L SL+ D SS EL+I D + SK+ IH +
Sbjct: 1709 L----------SLIPLDREE-SSLHELLIEAKDAG-----IPSLSATSKILIHVGDINDN 1752
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
T F +L F+ I EN IG+ II++ A D D Q E N
Sbjct: 1753 TPEF----------------ELSSYFIKISENSKIGSKIIRILATDKDKDAELQYSLESN 1796
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNI 1029
E+ IP F IN G + VA + E EFR + D G + +
Sbjct: 1797 DEITIP--------------FRINVATGWITVAGKVNREENEEFRFFVKVTD-GEKSSKV 1841
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
V + V+D ND+ P+ + V + + ++ ++ D D ++ +L + + S+
Sbjct: 1842 IVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHVINVHDLD--KSDHLKFSLNNSNL 1899
Query: 1090 DL 1091
+L
Sbjct: 1900 NL 1901
Score = 60.9 bits (141), Expect = 3e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 8/147 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK--LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A D+D G+ + Y++++ +D +F LDS +GSL K D + + + + +
Sbjct: 653 IQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRS-----YTFE 707
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+A L P KT I + D+NDN+P+F +Y +I +++Q D D
Sbjct: 708 YEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDV 767
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLT 362
+N + Y L + F +D +G +T
Sbjct: 768 -KNQKLQYHLLNYHDFFQLDKETGKVT 793
Score = 60.1 bits (139), Expect = 5e-07
Identities = 52/160 (32%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
PLDRE + M +I S I + I + D NDN P+F I E + I
Sbjct: 80 PLDRESENAIDMLIIT-------SPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPI 132
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG-------DSLDR 855
G +++ ATD DEG N + D G+V+ G LDR
Sbjct: 133 GWRVQISG---ATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDR 189
Query: 856 EKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
E + +Y + L A D G LSS L I+I D NDN P F
Sbjct: 190 ETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF 229
Score = 59.7 bits (138), Expect = 6e-07
Identities = 64/259 (24%), Positives = 113/259 (43%), Gaps = 22/259 (8%)
Query: 136 RGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDK 195
R + I I D DK + ++ S ++ +++G L+S + + +R + DAG
Sbjct: 1871 RSVEIIHVINVHDLDKSDHLKFSLNNSNLNLSENGEITLKSPLQTAVPVRVTVSDDAGHV 1930
Query: 196 EFQLVIMASGKRIHKEILFPEPIHAI------DQDLGV----GATLRYELISGNDRKLFS 245
F + R H + F E + + +Q+L V G ++RY ++S R
Sbjct: 1931 AFMEYLFHPHSRKHFPV-FVEKLDTVSVREHDEQELAVFKANGDSIRYSIVS---RCSDH 1986
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
L+ + L+ + LDAE + F++ N PL T + I+++D+NDN P
Sbjct: 1987 LEMEKSTGILKTKSSLDAEEYSECLVFIIATTYFD-NKPLSTI-TKATIKIVDINDNSPR 2044
Query: 306 FEVDFYNISIVENLPNGFSVL-QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVR 364
F+ Y ++ EN +G ++ V+A D D+ + D F + +VR
Sbjct: 2045 FDQQLYRFNVTEN--SGPKLIGHVIARDIDRSSRVFYEIVGGDANHEFMVTESGQIESVR 2102
Query: 365 NQTVLDREAHSSLRMKVYA 383
+ LDRE S + V A
Sbjct: 2103 D---LDRETKSEYHLIVEA 2118
Score = 56.4 bits (130), Expect = 6e-06
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 9/163 (5%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
H I +D+ + + YE++ G+ F V S +E DLD E + + L V+A
Sbjct: 2065 HVIARDIDRSSRVFYEIVGGDANHEFM---VTESGQIESVRDLDRETKSE---YHLIVEA 2118
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P + V + +LD +DN P F F+ + + E++ G V+Q+ A+D D+ N
Sbjct: 2119 IDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFH-VEVPEDVRIGEPVIQLSASDADEHSN 2177
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
F F +D +G + V + LD E S R+KV
Sbjct: 2178 HRFELDGGGEGIPFRVDENTGMVFVNDS--LDFEKKQSYRIKV 2218
Score = 56.0 bits (129), Expect = 7e-06
Identities = 88/330 (26%), Positives = 135/330 (40%), Gaps = 32/330 (9%)
Query: 681 HSPII----FHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDDIAIAED 735
HSPI HV EN A IG IF + +G +G V + I + D D I +
Sbjct: 629 HSPICQITEIHVLEN---APIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDS 685
Query: 736 --GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G++ + K D EK+ Y A+ + G S TI+IED NDN P F Y
Sbjct: 686 TSGSLRSLKAFDAEKKRSYTFEYEAK-DLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYT 744
Query: 794 GFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I G + I++A D D + N Y L + F +D+ TG V I D
Sbjct: 745 ATIS-----GKSNETVAIVQANDNDVDVKNQKLQYHLLNY-HDFFQLDKETGKVTTIQDV 798
Query: 853 LDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
+++ +S V D+ L S+ L++ + + + N + +RI + K+
Sbjct: 799 PMTWQRLNISISAVNMDSERFLQSKTFLLVTVTSSSKLAVQLN---SGNLIRIFKNDKIG 855
Query: 912 GTAGFTIIEVKPKNKFA-----LDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
G I ++ L VD G + LI N +T + + + NG+
Sbjct: 856 EKVGHLDIASSETVYWSTLDPRLHVDSSGNIILIRRNAKQASTGFDI----ILTSENGEK 911
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+ N EV S+ S D +V V+NE
Sbjct: 912 TEKVNFEVEFVDSERSEDVEKVMD-IVLNE 940
Score = 55.6 bits (128), Expect = 1e-05
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 17/174 (9%)
Query: 1013 FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
F + + D L+ + + D+ND+ P F + Y FNV E +++G V A D
Sbjct: 2013 FIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTE-NSGPKLIGHVIARDI 2071
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
D +++ + Y I D + F ++ + SV +LDRET+ +Y L V A D+G
Sbjct: 2072 D--RSSRVFYEIVGGDANHEFMVTESGQIESVR-DLDRETKSEYHLIVEAIDDG-KPRRR 2127
Query: 1133 XXXXXXXXXXDVNDNSPKFYAF------------DELLEWKHPEADELSNHNFE 1174
D +DN+P+F + +++ +ADE SNH FE
Sbjct: 2128 GNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFE 2181
Score = 55.2 bits (127), Expect = 1e-05
Identities = 55/200 (27%), Positives = 87/200 (43%), Gaps = 25/200 (12%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SE 1012
A DLD G NG + Y S LS + F +N G ++ L E S
Sbjct: 1676 AEDLDEGQNGLVTY----------SILSGNT----SLFAVNSTTGDILSLIPLDREESSL 1721
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
L I A D G +L+ + + V D+ND+ P F+ + Y + E + ++ AT
Sbjct: 1722 HELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILAT 1781
Query: 1071 DADFGQNANLTYFIQPSD-TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
D D ++A L Y ++ +D +PF I+ TG ++V G+++RE +++ V D
Sbjct: 1782 DKD--KDAELQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKVTDG---- 1835
Query: 1130 XXXXXXXXXXXXXDVNDNSP 1149
D NDN P
Sbjct: 1836 EKSSKVIVEIHVEDFNDNHP 1855
Score = 54.8 bits (126), Expect = 2e-05
Identities = 73/295 (24%), Positives = 118/295 (40%), Gaps = 32/295 (10%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA-PIGPSLTIPLTVP 135
+S T+ I D+NDN P F Y V E +G K +IA I S + +
Sbjct: 2025 LSTITKATIKIVDINDNSPRFDQQLYRFNVTE--NSGPKLIGHVIARDIDRSSRVFYEIV 2082
Query: 136 RG-------LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
G +T I + RD S+ H IV DDG + ++ VL
Sbjct: 2083 GGDANHEFMVTESGQIESV-RDLDRETKSEYHL-IVEAIDDGKPRRRGNTTVIVT---VL 2137
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAID-QDLGVGATLRYELISGNDRKLFSLD 247
D D F + + +++ EP+ + D + R+EL G + F +D
Sbjct: 2138 DEDDNAPRFSRIFHVE---VPEDVRIGEPVIQLSASDADEHSNHRFELDGGGEGIPFRVD 2194
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
G +F+ LD + + + + +L + + + + + D+NDN P FE
Sbjct: 2195 ENTGMVFVNDSLDFEKKQSYRIKV--------KLTDGAWLIETSLFVNVKDVNDNAPIFE 2246
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT 362
Y + I E N + Q A+D D NG+ Y + P F I+P +G L+
Sbjct: 2247 KPEY-LFISEE--NSAEIGQFHASDMDSENNGKIRYSVTSP--YFKIEPSTGVLS 2296
Score = 54.8 bits (126), Expect = 2e-05
Identities = 86/335 (25%), Positives = 136/335 (40%), Gaps = 31/335 (9%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
P F Y F V N G +G + D + V Y+++ G + F V E SG I
Sbjct: 2043 PRFDQQLYRFNVTENSG-PKLIGHVIARDIDRSSRVFYEIVGG-DANHEFMVTE-SGQIE 2099
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
V DL R + Y A+ + N TV +V V DE + + IFHV E
Sbjct: 2100 SVRDLDRETKSEYHLIVEAIDDGKPRRR-GNTTV-IVTVLDEDDNAPRFSR---IFHV-E 2153
Query: 691 NSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD 750
IG+ +S+ + N RF + + G +F LD EK+
Sbjct: 2154 VPEDVRIGEPV-IQLSASDADEHSNHRFELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQ 2212
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYI--EDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
YR+ V + GA + + ++++ +D NDN P+FE Y ENS EI
Sbjct: 2213 SYRIKV------KLTDGAWLIETSLFVNVKDVNDNAPIFEKPEYLFISEENS---AEIGQ 2263
Query: 809 DNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
A+D D N Y++ F ++ +TGV+ L + + L + A
Sbjct: 2264 ---FHASDMDSENNGKIRYSV---TSPYFKIEPSTGVLSRFRQQLPQP---LMSLKVTAT 2314
Query: 869 DTGGLSSEAELIIMIGDEND-NKPEFNQIEENSKV 902
D G + ++ + D++ K + +I E +KV
Sbjct: 2315 DHGVPRLQKTVLAHLVDKSSFGKIKQRRIRETTKV 2349
Score = 54.4 bits (125), Expect = 2e-05
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 22/172 (12%)
Query: 732 IAEDGTIFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-- 787
+ DG +F + LDRE RD+Y M + A ++GV + + I I D NDNPP F
Sbjct: 173 VQSDGFLFLEVTGKLDRETRDLYSMRLTA-IDQGVPELSSSCHLNILILDINDNPPNFGI 231
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG--KEMFDV-DENTG 844
T + N+K+ + + ATD D N+L Y + G EMF + DEN
Sbjct: 232 RSLTLNWNGLPNTKLFS-------LNATDLDSNENSLLTYRILPSGPTSEMFSISDENIL 284
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
V + + L R + + ARD+G LS+ +++ + N+++P N
Sbjct: 285 VTQNNTECLQR-----CEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNIN 331
Score = 54.4 bits (125), Expect = 2e-05
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 12/164 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F++ E G + R L E SE+ L + A+D G N +V V V D +D+ P F +
Sbjct: 2090 FMVTES-GQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSR 2148
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
++ E+ + V+ ++ A+DAD +++N + + +PF + TG++ VN
Sbjct: 2149 IFHVEVPEDVRIGEPVI-QLSASDAD--EHSNHRFELDGGGEGIPFRVDENTGMVFVNDS 2205
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LD E + Y + V D DVNDN+P F
Sbjct: 2206 LDFEKKQSYRIKVKLTDG----AWLIETSLFVNVKDVNDNAPIF 2245
Score = 52.0 bits (119), Expect = 1e-04
Identities = 42/139 (30%), Positives = 56/139 (40%), Gaps = 8/139 (5%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF----- 1083
I + + V DVND+ P+F + E + ATD D G+N + +
Sbjct: 101 IHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDS 160
Query: 1084 IQPSDTDLPFEISPLTGVL--SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
+ DT PF I G L V G+LDRET D Y + + A D G
Sbjct: 161 LATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQG-VPELSSSCHLNILI 219
Query: 1142 XDVNDNSPKFYAFDELLEW 1160
D+NDN P F L W
Sbjct: 220 LDINDNPPNFGIRSLTLNW 238
Score = 51.6 bits (118), Expect = 2e-04
Identities = 77/355 (21%), Positives = 145/355 (40%), Gaps = 55/355 (15%)
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ FN+ E +GK+ A G ++ + IQ D D F ISP G + N LD
Sbjct: 1560 FEFNISETADRFTEVGKIVILGA--GLEGSV-FRIQ--DNDYNFTISPFDGTIFTNSPLD 1614
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
E Y + A D ND +P+F D ++ K +EL
Sbjct: 1615 FENIKTYRFNITA--------GKSTSQVIIHVTDENDEAPRFITGD-VVNLK--VLEELD 1663
Query: 1170 NHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNL- 1227
++ ++ + + ++E T + + N + F + + G IL +P + + +L
Sbjct: 1664 TVSYPLIIGSSIAE-DLDEGQNGLVTYSILSGNTSLFAVNSTTGDILSLIPLDREESSLH 1722
Query: 1228 ---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
G+PSLS+T+ +++ V D+ D + P F Y ++I EN +++
Sbjct: 1723 ELLIEAKDAGIPSLSATSKILIHVGDIND-----NTPEFELSSYFIKISENSKIGSKIIR 1777
Query: 1279 LNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
+ T+ ++ +++Y + E++ +I F I+ G + + +RE + + V+
Sbjct: 1778 ILATDKDKDAELQYSL--ESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVK---- 1831
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPT 1393
V +G V V + ++D NDN P + N + PT
Sbjct: 1832 ----------------VTDGEKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPT 1870
Score = 50.8 bits (116), Expect = 3e-04
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF-TYQL------D 346
I++LD+NDN P F +D + I E P G+ V ATD D+G+NG Y+L
Sbjct: 105 IDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATV 164
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
D F I G+L + LDRE M++ A
Sbjct: 165 DTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTA 201
Score = 50.0 bits (114), Expect = 5e-04
Identities = 102/418 (24%), Positives = 169/418 (40%), Gaps = 65/418 (15%)
Query: 929 LDVDQLGPLFLI-------PENIPIGTTIIKLNALDLDSGLNGQI-RYEFNSEVYIPPSK 980
LDV+ P+F I PE PIG + A D D G NG I +YE + S
Sbjct: 108 LDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYE------LVDSL 161
Query: 981 LSADALEVKRYFVINERHGHVI--VARSLPPESE--FRLNISALDGG--NLNDNISVRVF 1034
+ D + F I + G + V L E+ + + ++A+D G L+ + + +
Sbjct: 162 ATVDTMSP---FGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNIL 218
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-DTDLPF 1093
+ D+ND+ P F N T+ L ++ATD D +N+ LTY I PS T F
Sbjct: 219 ILDINDNPPNFGIRSLTLNWNGLPNTK--LFSLNATDLDSNENSLLTYRILPSGPTSEMF 276
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP---- 1149
IS +++ N + E + V ARD+G N++ P
Sbjct: 277 SISDENILVTQN---NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYG-NEHEPNINI 332
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
+FY D PE + N +++ ++ + + + P+G AN T +I N
Sbjct: 333 RFYPSDYPFIIVQPE-----DVNGKTLAILSI----TDSDGPLG-------ANSTIWIEN 376
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSST----AILMVTVAD---VPDEVEMSDKPVFISRYY 1262
GN ++SL R++ L + + + IL D D + + +F +Y
Sbjct: 377 GNEQSIFSLISRQSINILTVKHVENANQEQYILEFRANDGQSPADRITRKELKIFFKKYV 436
Query: 1263 E-----LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTL 1315
+ +E E +V + V + H E ++D+ F IDP NG +
Sbjct: 437 KSTQIHVERESHVTVEKDTVPGSFVAHVETNCTDMCSFELANSDV---FKIDPFNGII 491
Score = 48.8 bits (111), Expect = 0.001
Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 15/161 (9%)
Query: 220 AIDQDLGVGATL-RYELISG----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
A D D G T+ +YEL+ + F + +G LFLE LD E + + +
Sbjct: 141 ATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLDRETR---DLYSM 197
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
++ A P ++ + I +LD+NDN P F + ++ LPN + + ATD D
Sbjct: 198 RLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLN-WNGLPN-TKLFSLNATDLD 255
Query: 335 QGENGEFTYQLDDPKG----AFSIDPRSGWLTVRNQTVLDR 371
EN TY++ P G FSI + +T N L R
Sbjct: 256 SNENSLLTYRI-LPSGPTSEMFSISDENILVTQNNTECLQR 295
Score = 45.6 bits (103), Expect = 0.011
Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 7/155 (4%)
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
G V V +++ S+F L N + + VK +N H P+ + T +V E
Sbjct: 589 GSVFVGKTIT--SDFVTLPVTLVNRNTTQTSIITLIVKPLNQHSPICQIT--EIHVLENA 644
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ G++ A D D G + ++Y I + D D F + +G L D E + Y
Sbjct: 645 PIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSY 704
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
A+D G DVNDN PKF
Sbjct: 705 TFEYEAKDLGTPSKTTNCPATIFIE-DVNDNVPKF 738
Score = 45.2 bits (102), Expect = 0.014
Identities = 55/260 (21%), Positives = 107/260 (41%), Gaps = 19/260 (7%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFK 512
N ++P+ + E + NA +GT+ G+++A D D G +G+V Y + S+ F
Sbjct: 627 NQHSPI---CQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSD-DYDGIFH 682
Query: 513 INPNTGTV-SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP 571
++ +G++ S+ + R F + PS+ A + IE ++P
Sbjct: 683 LDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPATIFIEDV------NDNVP 736
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLHGYEEGVPFAVEERSGVIT 630
F Y + ++ Q ND +N + Y LL+ ++ F +++ +G +T
Sbjct: 737 KFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLLNYHDF---FQLDKETGKVT 793
Query: 631 VVDDL-SRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
+ D+ + R AV + L T V V + + V L + IF K
Sbjct: 794 TIQDVPMTWQRLNISISAVNMDSERFLQSKTFLLVTVTS-SSKLAVQLNSGNLIRIF--K 850
Query: 690 ENSAGAAIGQIFHTNMSSIY 709
+ G +G + + ++Y
Sbjct: 851 NDKIGEKVGHLDIASSETVY 870
Score = 44.8 bits (101), Expect = 0.018
Identities = 43/176 (24%), Positives = 78/176 (44%), Gaps = 19/176 (10%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
T+ T+I VKP N+ + + Q+ + ++ EN PIGT ++ A D DSGL+G + Y
Sbjct: 616 TSIITLI-VKPLNQHS-PICQITEIHVL-ENAPIGTIFGRIQARDEDSGLSGVVSY---- 668
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDN 1028
K+ + + F ++ G + ++ E + + A D G + N
Sbjct: 669 -------KILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTN 721
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+F++DVND+ P F +Y + + + + D D +N L Y +
Sbjct: 722 CPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDV-KNQKLQYHL 776
Score = 44.0 bits (99), Expect = 0.032
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV-LYDL 499
S +++ + +LD NDN+P+F P ++ + A +G + A DPD G+NG + Y+L
Sbjct: 99 SIIHILIDVLDVNDNSPIF-PIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYEL 157
Query: 500 -QRTSNLTITSPFKINPNTG 518
+ + SPF I + G
Sbjct: 158 VDSLATVDTMSPFGIVQSDG 177
Score = 42.7 bits (96), Expect = 0.075
Identities = 47/175 (26%), Positives = 79/175 (45%), Gaps = 21/175 (12%)
Query: 225 LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
LG G I ND F++ +G++F LD + N++ T+ + A +
Sbjct: 1580 LGAGLEGSVFRIQDNDYN-FTISPFDGTIFTNSPLDFE---NIK--TYRFNITAGK---- 1629
Query: 285 LKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQV---MATDKDQGENGE 340
+ ++V I + D ND P F D N+ ++E L L + +A D D+G+NG
Sbjct: 1630 ---STSQVIIHVTDENDEAPRFITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGL 1686
Query: 341 FTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
TY L F+++ +G + + LDRE S + + AK+ PS+ T
Sbjct: 1687 VTYSILSGNTSLFAVNSTTG--DILSLIPLDREESSLHELLIEAKDAGIPSLSAT 1739
Score = 40.3 bits (90), Expect = 0.40
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 17/100 (17%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
FVNV+ D NDN P+F S +++A+ IG+ A D D NG + Y
Sbjct: 2232 FVNVK----DVNDNAPIFEKPEYLFISEENSAE----IGQFHASDMDSENNGKIRY---- 2279
Query: 502 TSNLTITSP-FKINPNTGTVSVAESPILEGRHALFVEASD 540
++TSP FKI P+TG +S + + +L V A+D
Sbjct: 2280 ----SVTSPYFKIEPSTGVLSRFRQQLPQPLMSLKVTATD 2315
Score = 39.1 bits (87), Expect = 0.92
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTE- 1283
++LG PS ++ + + DV D V P F SRYY I N V +V N +
Sbjct: 711 KDLGTPSKTTNCPATIFIEDVNDNV-----PKFGSRYYTATISGKSNETVAIVQANDNDV 765
Query: 1284 HYENFKMRYYILNEND 1299
+N K++Y++LN +D
Sbjct: 766 DVKNQKLQYHLLNYHD 781
Score = 38.7 bits (86), Expect = 1.2
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
L N T + + + + LN + P ++ I ++EN P G ++ A D+D G +G
Sbjct: 608 LVNRNTTQTSIITLIVKPLNQHSPICQIT--EIHVLENAPIGTIFGRIQARDEDSGLSGV 665
Query: 341 FTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+Y++ DD G F +D SG ++R+ D E S + AK+
Sbjct: 666 VSYKILTKSDDYDGIFHLDSTSG--SLRSLKAFDAEKKRSYTFEYEAKD 712
>UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 970
Score = 103 bits (246), Expect = 5e-20
Identities = 120/476 (25%), Positives = 188/476 (39%), Gaps = 24/476 (5%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ + + +VEV +LD NDN+P F P + +A +GT I A D D
Sbjct: 105 TFDVAFVSAEQFELFHVEVEVLDVNDNSPEF-PRAECTVEISESAALGTRIALDAAEDSD 163
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER 548
+G N + Y+L S+ +I +++ V + A F
Sbjct: 164 VGSNSIQSYELSENSHFSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPP 223
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
R VT++V K + P F + Y V + + + + D E V
Sbjct: 224 RSGSTNVTVKV----KDANDNSPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEGLNGQV 279
Query: 607 SYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNAT 663
Y+ + F ++ ++G +T+ + + Y+ + A N + V
Sbjct: 280 VYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSVCKII 339
Query: 664 VHVVDVNDERGVLLKGAHSPI---IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+++ DVND ++ + + + + HV E + + + NG + L
Sbjct: 340 INIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANGQVSCT-LN 398
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
+ A TI T PLDREK Y +TV+AE + GV + Q + + D
Sbjct: 399 GGHGNFRLKRAYEGSYTIVTMAPLDREKIAEYNLTVVAE-DFGVPPLRTVTQYIVRLTDV 457
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEMF 837
NDN P F YEGFI EN GT I I A+D D G N Y LF F
Sbjct: 458 NDNAPAFSAKIYEGFIEENQLPGTYI---TTILASDQDSGLNGEITYELFDSDTNSVSRF 514
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+ G V + S + E L + A D G L + A LII + D+NDN P
Sbjct: 515 AIMNQAGNV-YALQSFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTP 569
Score = 95.9 bits (228), Expect = 8e-18
Identities = 140/630 (22%), Positives = 263/630 (41%), Gaps = 91/630 (14%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAG--IYQVTIYIEDENDNPPVFEHATY 792
DG + ++ +DRE+ + F+ +S ++ V + + D NDN P F A
Sbjct: 81 DGRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDNSPEFPRAEC 140
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
I E++ +GT I +D A D+D G+N++ + +++ EN+ F D
Sbjct: 141 TVEISESAALGTRIALD---AAEDSDVGSNSI----------QSYELSENS---HFSIDV 184
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNG 912
+ R + Y ++ ++ + + ++ + + P +G
Sbjct: 185 ITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPPR------------------SG 226
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
+ T+ +VK N + D +PE+ P+ ++ LNA+D D GLNGQ+ YEF
Sbjct: 227 STNVTV-KVKDANDNSPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGK 285
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDN 1028
+V E+++ F ++ + G++ + + E E + +++ A D G+ +
Sbjct: 286 QV----------TTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSV 335
Query: 1029 ISVRVFVKDVNDHFP------VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
+ + ++DVND+ P + T +V EA ++ + D D G N ++
Sbjct: 336 CKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANGQVSC 395
Query: 1083 FIQPSDTDLPFEISPLTGVLSVN-GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
+ + + + V LDRE +Y LTVVA D G
Sbjct: 396 TLNGGHGNFRLKRAYEGSYTIVTMAPLDREKIAEYNLTVVAEDFG-VPPLRTVTQYIVRL 454
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA 1201
DVNDN+P F A ++ E E ++L +++ A+ +++ G ++F
Sbjct: 455 TDVNDNAPAFSA--KIYE-GFIEENQLPGTYITTIL------ASDQDSGLNGEITYELFD 505
Query: 1202 NDTDFIGN-------GNGLILYS--------LPQRKNQQNLGLPSLSSTAILMVTVADVP 1246
+DT+ + GN L S L R + G P L + AIL++ V D
Sbjct: 506 SDTNSVSRFAIMNQAGNVYALQSFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQN 565
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE---NFKMRYYILNENDTDIR 1303
D P I+ E+++ + P +V+ + + + N ++ Y I + D
Sbjct: 566 DNTPFITHPPLINGSAEIQLPRDA-PPGYIVTRIIAKDSDAGLNAELTYKIYDGGDFG-- 622
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
F IDP G +Y+ R + D ++V+V
Sbjct: 623 --FAIDPNTGEIYINRKITYDEYDLWKVLV 650
Score = 79.0 bits (186), Expect = 9e-13
Identities = 105/441 (23%), Positives = 177/441 (40%), Gaps = 26/441 (5%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
NV V + DANDN+P+F S+ Y + + V ++ + A+DPD G NG V+Y+ +
Sbjct: 229 NVTVKVKDANDNSPLFDHSH-YSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGKQV 287
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
I FK++ TG +++ +SP+ E + + V+A+D NP S+ + I +
Sbjct: 288 TTEIRQLFKLDYKTGYLTL-QSPVDYEDETTYEIDVQATDLGHNPVP---SVCKIIINI- 342
Query: 561 RGTKGNKPD-----IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
R N P+ I + I ++ I+ D VS L G+
Sbjct: 343 RDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANGQVSCTLNGGHG 402
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERG 674
E S I + L R Y+ VA L VT V + DVND
Sbjct: 403 NFRLKRAYEGSYTIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVRLTDVNDNAP 462
Query: 675 VLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
+ I +EN G I I ++ S NG ++ V+ +
Sbjct: 463 AFSAKIYEGFI---EENQLPGTYITTILASDQDSGL-NGEITYELFDSDTNSVSRFAIMN 518
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G ++ + + E + V A ++G + I + D+NDN P H
Sbjct: 519 QAGNVYALQSFNYEVTKRLDLRVQAS-DRGWPQLHNNAILIINVVDQNDNTPFITHPPLI 577
Query: 794 GFIMENSKIGTEIKMDNIIK---ATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
E ++ + I+ A D+D G NA Y ++ G F +D NTG + +I
Sbjct: 578 NGSAE-IQLPRDAPPGYIVTRIIAKDSDAGLNAELTYKIYDGGDFGFAIDPNTGEI-YIN 635
Query: 851 DSLDREKKIMYKLSLVARDTG 871
+ ++ ++K+ + D G
Sbjct: 636 RKITYDEYDLWKVLVTVNDNG 656
Score = 76.2 bits (179), Expect = 7e-12
Identities = 67/241 (27%), Positives = 116/241 (48%), Gaps = 24/241 (9%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIAN 722
V V+DVND P E S AA+G + + G+ +++ + ++
Sbjct: 123 VEVLDVNDN------SPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELSE 176
Query: 723 QQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ D+ DG + + K LDRE R + + ++A + G +G VT+ ++
Sbjct: 177 NSHFSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAA-DGGHPPRSGSTNVTVKVK 235
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-----EG 833
D NDN P+F+H+ Y + E++ + + +D + A D DEG N +Y FG E
Sbjct: 236 DANDNSPLFDHSHYSVDVPEDTPV-EALLLD--LNAIDPDEGLNGQVVYE-FGKQVTTEI 291
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+++F +D TG + + +D E + Y++ + A D G + S ++II I D NDN P
Sbjct: 292 RQLFKLDYKTGYLT-LQSPVDYEDETTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPP 350
Query: 892 E 892
E
Sbjct: 351 E 351
Score = 72.9 bits (171), Expect = 6e-11
Identities = 84/299 (28%), Positives = 120/299 (40%), Gaps = 25/299 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
LV G S +VTV ++D NDN P+F + Y V V E TP +A + + I P
Sbjct: 214 LVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPV--EALLLDLNAIDP 271
Query: 127 S--LTIPLTVPRGLTIFKDIRA-FDRD---------KPNTPNSDVHYSI-VSGNDDGHFA 173
L + G + +IR F D P + Y I V D GH
Sbjct: 272 DEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNP 331
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGA 229
+ S K ++ +R V D + + G E P+ + A+ D+D G
Sbjct: 332 VPSVCKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANG 391
Query: 230 TLRYELISGNDRKLFSLD-SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+ L G+ F L + GS + LD E + N L V A P
Sbjct: 392 QVSCTLNGGHGN--FRLKRAYEGSYTIVTMAPLDREKIAEYN---LTVVAEDFGVPPLRT 446
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+ + L D+NDN P F Y I EN G + ++A+D+D G NGE TY+L D
Sbjct: 447 VTQYIVRLTDVNDNAPAFSAKIYEGFIEENQLPGTYITTILASDQDSGLNGEITYELFD 505
Score = 67.7 bits (158), Expect = 2e-09
Identities = 44/171 (25%), Positives = 86/171 (50%), Gaps = 8/171 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + YEL + + + V+G + E L + + +A F L++ A+
Sbjct: 159 AEDSDVGSNSIQSYELSENSHFSIDVITRVDGVKYAELVLVKELDREARA-FFALKLVAA 217
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ V +++ D NDN P F+ Y++ + E+ P +L + A D D+G NG
Sbjct: 218 DGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEGLNG 277
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ Y+ + + F +D ++G+LT+ Q+ +D E ++ + V A +
Sbjct: 278 QVVYEFGKQVTTEIRQLFKLDYKTGYLTL--QSPVDYEDETTYEIDVQATD 326
Score = 67.7 bits (158), Expect = 2e-09
Identities = 62/196 (31%), Positives = 90/196 (45%), Gaps = 21/196 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT I + A D DSGLNG+I YE +D V R+ ++N+ G
Sbjct: 473 IEENQLPGTYITTILASDQDSGLNGEITYEL----------FDSDTNSVSRFAIMNQA-G 521
Query: 1000 HVIVARSLPPESEFRLN--ISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+V +S E RL+ + A D G L++N + + V D ND+ P
Sbjct: 522 NVYALQSFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSA 581
Query: 1056 EAQYTR-----RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
E Q R ++ ++ A D+D G NA LTY I D F I P TG + +N ++
Sbjct: 582 EIQLPRDAPPGYIVTRIIAKDSDAGLNAELTYKIYDGG-DFGFAIDPNTGEIYINRKITY 640
Query: 1111 ETEDKYILTVVARDNG 1126
+ D + + V DNG
Sbjct: 641 DEYDLWKVLVTVNDNG 656
Score = 62.5 bits (145), Expect = 9e-08
Identities = 99/372 (26%), Positives = 151/372 (40%), Gaps = 41/372 (11%)
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
S ++ L V +EV N P+ P A + + +GT + DA E +D
Sbjct: 112 SAEQFELFHVEVEVL-DVNDNSPEFPR---AECTVEISESAALGTRIAL----DAAEDSD 163
Query: 606 VSYDLLHGYE--EGVPFAVEERSGV-------ITVVDDLSRYNRPMYDFEAVALQE-NAN 655
V + + YE E F+++ + V + +V +L R R + + VA +
Sbjct: 164 VGSNSIQSYELSENSHFSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPP 223
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
S TN TV V D ND + HS V E++ A+ + N G
Sbjct: 224 RSGSTNVTVKVKDANDNSPLF---DHSHYSVDVPEDTPVEAL--LLDLNAIDPDEGLNGQ 278
Query: 716 VRFLIANQQDVTDDIAIA-----EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
V + Q VT +I + G + Q P+D E Y + V A + G +
Sbjct: 279 VVYEFGKQ--VTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQAT-DLGHNPVPSV 335
Query: 771 YQVTIYIEDENDNPP--VFEHATY--EGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
++ I I D NDNPP + T +G + G +I + +I D D G N
Sbjct: 336 CKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVA-LISIKDKDTGANGQVS 394
Query: 827 YTLFGEGKEMFDVDEN-TGVVKFIGDS-LDREKKIMYKLSLVARDTG--GLSSEAELIIM 882
TL G G F + G + + LDREK Y L++VA D G L + + I+
Sbjct: 395 CTLNG-GHGNFRLKRAYEGSYTIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVR 453
Query: 883 IGDENDNKPEFN 894
+ D NDN P F+
Sbjct: 454 LTDVNDNAPAFS 465
Score = 58.8 bits (136), Expect = 1e-06
Identities = 51/180 (28%), Positives = 88/180 (48%), Gaps = 19/180 (10%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++AID D G+ + YE ++ R+LF LD G L L+ +D + E T+ +
Sbjct: 266 LNAIDPDEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDE-----TTYEI 320
Query: 275 QVQASQL-NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN-----GFSVLQV 328
VQA+ L +NP+ + ++ I + D+NDN PE + S+ + + + G +L
Sbjct: 321 DVQATDLGHNPVPSV-CKIIINIRDVNDNPPEIIITSIT-SVTDGVAHVSEATGPDILVA 378
Query: 329 MAT--DKDQGENGEFTYQLDDPKGAFSID-PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ + DKD G NG+ + L+ G F + G T+ LDRE + + V A++
Sbjct: 379 LISIKDKDTGANGQVSCTLNGGHGNFRLKRAYEGSYTIVTMAPLDREKIAEYNLTVVAED 438
Score = 58.4 bits (135), Expect = 1e-06
Identities = 45/161 (27%), Positives = 75/161 (46%), Gaps = 13/161 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A DQD G+ + YEL + + F++ + G+++ + + + L L+
Sbjct: 486 ILASDQDSGLNGEITYELFDSDTNSVSRFAIMNQAGNVYALQSFNYEVTKRLD-----LR 540
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYN----ISIVENLPNGFSVLQVMA 330
VQAS P A + I ++D NDN P N I + + P G+ V +++A
Sbjct: 541 VQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPRDAPPGYIVTRIIA 600
Query: 331 TDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRNQTVLD 370
D D G N E TY++ D F+IDP +G + + + D
Sbjct: 601 KDSDAGLNAELTYKIYDGGDFGFAIDPNTGEIYINRKITYD 641
Score = 47.6 bits (108), Expect = 0.003
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 24/154 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P S + + V V D D + P+F +Y +++ E+ L+ LN + E
Sbjct: 220 GHPPRSGSTNVTVKVKDAND-----NSPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEG 274
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y + T+IR+ F +D + G L L D E + TYE+ V+A +L
Sbjct: 275 LNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQA------TDLG 328
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
H P K+++ I+DVNDN P+
Sbjct: 329 HNPVPSV-----------CKIIINIRDVNDNPPE 351
Score = 45.2 bits (102), Expect = 0.014
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
VE+E+LD+NDN PEF + I E+ G + A D D G N +Y+L +
Sbjct: 121 VEVEVLDVNDNSPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELSE-NSH 179
Query: 352 FSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE 385
FSID + V+ + LDREA + +K+ A +
Sbjct: 180 FSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAAD 218
>UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37;
Clupeocephala|Rep: Protocadherin2-gamma-c6-sCP1 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 966
Score = 103 bits (246), Expect = 5e-20
Identities = 114/472 (24%), Positives = 185/472 (39%), Gaps = 36/472 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + VE+ + D NDN P F ++ + GT A D D+ N +
Sbjct: 108 ENPLQLHRVEIEIQDINDNPPTFHTKDVI-LKISELVAPGTRFSLESAEDLDVSSNSLKT 166
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + N V E + + H L + A D NP + SL
Sbjct: 167 YTLNNNDFFRLNVKTLKNGRKVPELVVEKALDREKQSIHELILTALDG-GNPVKSGTSLL 225
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
+ ++ + P F A Y+ V SV +I+ D E ++ Y
Sbjct: 226 QIIVQDINDNE------PKFEVASYKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFA 279
Query: 612 HGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVD 668
E V F V +G I V+ L + Y F+ A + N L ++ + ++D
Sbjct: 280 AHTPESVRNVFRVNVETGEIKVIGGLDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIID 339
Query: 669 VNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
ND ++L SP V EN+ + + N+ + G V I+
Sbjct: 340 ENDNPPEIILTSLPSP----VPENATVGTVVALI--NVKDLDSGNNGKVELTISTGAPFK 393
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ ++ T LDRE Y + ++A + GV S V + + D NDN PVF
Sbjct: 394 IITSFENHYSLITDSFLDRELNSEYNIEILAR-DLGVPSLITTKAVNVKVLDVNDNSPVF 452
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG------EGKEMFDVDE 841
++Y +I EN+ G + + ATD+D+ NA+ Y++ F ++
Sbjct: 453 SQSSYNVYINENNLAGFSLFS---VSATDSDQDKNAMLTYSVLDLSPNHVPASSYFYINS 509
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
G + + S D EK + + + A+D G LSS A + + I D+NDN P
Sbjct: 510 ENGTI-YSMSSFDYEKMKLISIVVQAKDQGSPSLSSNATVHVFILDQNDNAP 560
Score = 95.9 bits (228), Expect = 8e-18
Identities = 120/422 (28%), Positives = 181/422 (42%), Gaps = 46/422 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E + GT +A DLD N Y N+ + +L+ L+ R +
Sbjct: 139 ISELVAPGTRFSLESAEDLDVSSNSLKTYTLNNNDFF---RLNVKTLKNGR------KVP 189
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN-LNDNISV-RVFVKDVNDHFPVFKKTWYNFN-V 1054
++V ++L E + L ++ALDGGN + S+ ++ V+D+ND+ P F+ Y + V
Sbjct: 190 ELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIVQDINDNEPKFEVASYKASVV 249
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRE 1111
E+A + VL K+ ATD D G N + Y P F ++ TG + V G LD E
Sbjct: 250 EKATFDLSVL-KIKATDPDEGLNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIGGLDYE 308
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNH 1171
T+ Y V A+D G D NDN P+ L PE +
Sbjct: 309 TKKSYTFDVCAKDKG-NPELEGQSSVQIDIIDENDNPPEIILTS--LPSPVPENATVGT- 364
Query: 1172 NFESVMMIPVYKATIEENAPIGTTVA--KVFANDTDFIGNGNGLILYSLPQRK-NQQ--- 1225
V +I V N + T++ F T F N LI S R+ N +
Sbjct: 365 ---VVALINVKDLDSGNNGKVELTISTGAPFKIITSF-ENHYSLITDSFLDRELNSEYNI 420
Query: 1226 -----NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLN 1280
+LG+PSL +T + V V DV D + PVF Y + I EN A L S++
Sbjct: 421 EILARDLGVPSLITTKAVNVKVLDVND-----NSPVFSQSSYNVYINENNLAGFSLFSVS 475
Query: 1281 LT--EHYENFKMRYYI--LNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
T + +N + Y + L+ N F I+ NGT+Y + S D E ++V+A+
Sbjct: 476 ATDSDQDKNAMLTYSVLDLSPNHVPASSYFYINSENGTIYSMSSFDYEKMKLISIVVQAK 535
Query: 1337 RQ 1338
Q
Sbjct: 536 DQ 537
Score = 93.1 bits (221), Expect = 5e-17
Identities = 106/416 (25%), Positives = 182/416 (43%), Gaps = 27/416 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D NDN P F ++ Y+ S+ A + K+KA DPD G NG + Y +
Sbjct: 225 LQIIVQDINDNEPKFEVAS-YKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFAAHTP 283
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHA-LFVEASDQPANPSERRYSLAVVTIEVTRGT 563
++ + F++N TG + V E + + F + NP S ++++
Sbjct: 284 ESVRNVFRVNVETGEIKVIGGLDYETKKSYTFDVCAKDKGNPELEGQS----SVQIDIID 339
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV- 622
+ + P P+ + V N +GT V I V D N+ +L G PF +
Sbjct: 340 ENDNP--PEIILTSLPSPVPENATVGTVVALINVKDLDSGNNGKVELT--ISTGAPFKII 395
Query: 623 ---EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA-TVHVVDVNDERGVLLK 678
E +IT L R Y+ E +A I T A V V+DVND V +
Sbjct: 396 TSFENHYSLIT-DSFLDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQ 454
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG--TGNVRFLIANQQDVTDDIAI-AED 735
+++ ++ + N AG ++ + T+ S N T +V L N + I +E+
Sbjct: 455 SSYN--VYINENNLAGFSLFSVSATD-SDQDKNAMLTYSVLDLSPNHVPASSYFYINSEN 511
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
GTI++ D EK + + V A+ ++G S + V ++I D+NDN P + +
Sbjct: 512 GTIYSMSSFDYEKMKLISIVVQAK-DQGSPSLSSNATVHVFILDQNDNAPAVIYPSTSMG 570
Query: 796 IMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVK 847
+ + ++ K ++ + A DAD G NA Y L +F V+ +TG V+
Sbjct: 571 SVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRLAEATDASLFSVNLHTGEVR 626
Score = 86.6 bits (205), Expect = 5e-15
Identities = 84/266 (31%), Positives = 123/266 (46%), Gaps = 29/266 (10%)
Query: 738 IFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ +K LDREK+ ++ + + A + V SG + Q I ++D NDN P FE A+Y+ +
Sbjct: 191 LVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQ--IIVQDINDNEPKFEVASYKASV 248
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDS 852
+E + + IKATD DEG N Y E +F V+ TG +K IG
Sbjct: 249 VEKATFDLSVLK---IKATDPDEGLNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIG-G 304
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LD E K Y + A+D G L ++ + I I DENDN PE S V
Sbjct: 305 LDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPV------PE 358
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFL-IPENIP--IGTTIIKLNALDLDSGLNGQIR 967
N T G + + K+ LD G + L I P I T+ +L DS L+ ++
Sbjct: 359 NATVGTVVALINVKD---LDSGNNGKVELTISTGAPFKIITSFENHYSLITDSFLDRELN 415
Query: 968 YEFNSEVYI----PPSKLSADALEVK 989
E+N E+ PS ++ A+ VK
Sbjct: 416 SEYNIEILARDLGVPSLITTKAVNVK 441
Score = 74.1 bits (174), Expect = 3e-11
Identities = 67/217 (30%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN +GT + +N DLDSG NG++ ++ P K+ + E Y +I +
Sbjct: 356 VPENATVGTVVALINVKDLDSGNNGKVELTISTGA---PFKIIT-SFE-NHYSLITDS-- 408
Query: 1000 HVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ R L SE+ + I A D G +L +V V V DVND+ PVF ++ YN + E
Sbjct: 409 --FLDREL--NSEYNIEILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYNVYINEN 464
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP----FEISPLTGVLSVNGELDRET 1112
L V ATD+D +NA LTY + S +P F I+ G + D E
Sbjct: 465 NLAGFSLFSVSATDSDQDKNAMLTYSVLDLSPNHVPASSYFYINSENGTIYSMSSFDYEK 524
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ V A+D G D NDN+P
Sbjct: 525 MKLISIVVQAKDQG-SPSLSSNATVHVFILDQNDNAP 560
Score = 66.5 bits (155), Expect = 5e-09
Identities = 56/182 (30%), Positives = 91/182 (50%), Gaps = 19/182 (10%)
Query: 223 QDLGVGA-TLRYELISGNDRKLFSLDSV-NG----SLFLEKELDLDAEHNLQANTFVLQV 276
+DL V + +L+ ++ ND ++ ++ NG L +EK LD + + + L +
Sbjct: 155 EDLDVSSNSLKTYTLNNNDFFRLNVKTLKNGRKVPELVVEKALDREKQ-----SIHELIL 209
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A NP+K+ + ++I + D+NDN P+FEV Y S+VE SVL++ ATD D+G
Sbjct: 210 TALDGGNPVKSGTSLLQIIVQDINDNEPKFEVASYKASVVEKATFDLSVLKIKATDPDEG 269
Query: 337 ENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSV 390
NGE Y + + F ++ +G + V LD E S V AK+ NP +
Sbjct: 270 LNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIGG--LDYETKKSYTFDVCAKDKGNPEL 327
Query: 391 VG 392
G
Sbjct: 328 EG 329
Score = 66.1 bits (154), Expect = 7e-09
Identities = 61/191 (31%), Positives = 84/191 (43%), Gaps = 14/191 (7%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G I LD E + Y V A+ +KG G V I I DENDNPP +
Sbjct: 295 ETGEIKVIGGLDYETKKSYTFDVCAK-DKGNPELEGQSSVQIDIIDENDNPPEIILTSLP 353
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS- 852
+ EN+ +GT + + N+ D D G N T+ G + I DS
Sbjct: 354 SPVPENATVGTVVALINV---KDLDSGNNGKVELTI-STGAPFKIITSFENHYSLITDSF 409
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LDRE Y + ++ARD G L + + + + D NDN P F+Q N V I+
Sbjct: 410 LDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYN--VYINE---- 463
Query: 911 NGTAGFTIIEV 921
N AGF++ V
Sbjct: 464 NNLAGFSLFSV 474
Score = 62.9 bits (146), Expect = 7e-08
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 13/176 (7%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
+DL G + EL + S L + LD E N + N +++ A L
Sbjct: 372 KDLDSGNNGKVELTISTGAPFKIITSFENHYSLITDSFLDRELNSEYN---IEILARDLG 428
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
P V +++LD+NDN P F YN+ I EN GFS+ V ATD DQ +N T
Sbjct: 429 VPSLITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLT 488
Query: 343 YQLDD------PKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSV 390
Y + D P + F I+ +G T+ + + D E + + V AK+ +PS+
Sbjct: 489 YSVLDLSPNHVPASSYFYINSENG--TIYSMSSFDYEKMKLISIVVQAKDQGSPSL 542
Score = 56.8 bits (131), Expect = 4e-06
Identities = 61/228 (26%), Positives = 99/228 (43%), Gaps = 27/228 (11%)
Query: 917 TIIEVKPKNKFALDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
++I K N LDV+ P+F I EN G ++ ++A D D N + Y
Sbjct: 431 SLITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLTY- 489
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI--SALDGGN--L 1025
S + + P+ + A + YF IN +G + S E ++I A D G+ L
Sbjct: 490 --SVLDLSPNHVPASS-----YFYINSENGTIYSMSSFDYEKMKLISIVVQAKDQGSPSL 542
Query: 1026 NDNISVRVFVKDVNDHFP--VFKKTWYNFNVEEAQYTR-----RVLGKVDATDADFGQNA 1078
+ N +V VF+ D ND+ P ++ T +V + R ++ KV A DAD G NA
Sbjct: 543 SSNATVHVFILDQNDNAPAVIYPSTSMG-SVSHQRMPRFAKAGHLVTKVTAVDADSGHNA 601
Query: 1079 NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
L Y + + F ++ TG + + + L + +DNG
Sbjct: 602 WLFYRLAEATDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNG 649
Score = 54.4 bits (125), Expect = 2e-05
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+++V I I+D NDNPP F I E GT +++ A D D +N+L YTL
Sbjct: 113 LHRVEIEIQDINDNPPTFHTKDVILKISELVAPGTRFSLES---AEDLDVSSNSLKTYTL 169
Query: 830 FGEGKEMFDVDENT-----GVVKFIGD-SLDREKKIMYKLSLVARDTGG--LSSEAELII 881
+ F ++ T V + + + +LDREK+ +++L L A D G S + L I
Sbjct: 170 --NNNDFFRLNVKTLKNGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQI 227
Query: 882 MIGDENDNKPEF 893
++ D NDN+P+F
Sbjct: 228 IVQDINDNEPKF 239
Score = 54.4 bits (125), Expect = 2e-05
Identities = 44/187 (23%), Positives = 80/187 (42%), Gaps = 9/187 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
I A D D G+ + Y + R +F ++ G + + LD + + ++
Sbjct: 261 IKATDPDEGLNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIGGLDYETK-----KSYTF 315
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A NP Q+ V+I+++D NDN PE + + EN G V + D D
Sbjct: 316 DVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVKDLD 375
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-PSVVGT 393
G NG+ + I ++ + LDRE +S +++ A++ PS++ T
Sbjct: 376 SGNNGKVELTISTGAPFKIITSFENHYSLITDSFLDRELNSEYNIEILARDLGVPSLITT 435
Query: 394 FADSQRI 400
A + ++
Sbjct: 436 KAVNVKV 442
Score = 49.6 bits (113), Expect = 6e-04
Identities = 77/343 (22%), Positives = 135/343 (39%), Gaps = 32/343 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTI 130
G ++ SV + I D NDN P + T V E G + + + G + +
Sbjct: 323 GNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVKDLDSGNNGKV 382
Query: 131 PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR----K 186
LT+ G FK I +F+ +S + + S + A + ++ + K
Sbjct: 383 ELTISTGAP-FKIITSFENHYSLITDSFLDRELNSEYNIEILARDLGVPSLITTKAVNVK 441
Query: 187 VLDYDAGDKEFQLV---IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL 243
VLD + F + + + LF + A D D A L Y ++ + +
Sbjct: 442 VLDVNDNSPVFSQSSYNVYINENNLAGFSLFS--VSATDSDQDKNAMLTYSVLDLSPNHV 499
Query: 244 -----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
F ++S NG+++ D + + + VQA +P ++ A V + +LD
Sbjct: 500 PASSYFYINSENGTIYSMSSFDYE-----KMKLISIVVQAKDQGSPSLSSNATVHVFILD 554
Query: 299 LNDNLPEFEVDFYNISIV--ENLPN----GFSVLQVMATDKDQGENGEFTYQLDDPKGA- 351
NDN P ++ V + +P G V +V A D D G N Y+L + A
Sbjct: 555 QNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRLAEATDAS 614
Query: 352 -FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
FS++ +G VR + + SS R+ + K+ + T
Sbjct: 615 LFSVNLHTG--EVRTKRAVSEHDDSSQRLVLEIKDNGDPIQST 655
Score = 48.0 bits (109), Expect = 0.002
Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLN 282
D+ A + + S ++R+ FS+DS G L + +D + A+ + LQ+ +
Sbjct: 52 DISDIAERKLRIASESNRQYFSVDSGKGDLVVNGRIDRETLCGQSASCLMPLQIV---IE 108
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NPL+ RVEIE+ D+NDN P F + I E + G A D D N T
Sbjct: 109 NPLQLH--RVEIEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKT 166
Query: 343 YQLDD 347
Y L++
Sbjct: 167 YTLNN 171
Score = 46.0 bits (104), Expect = 0.008
Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPS----NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V +LD NDN P V PS ++ M AK G ++ KV AVD D G N
Sbjct: 542 LSSNATVHVFILDQNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNA 601
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTV 520
+ Y R + T S F +N +TG V
Sbjct: 602 WLFY---RLAEATDASLFSVNLHTGEV 625
Score = 36.3 bits (80), Expect = 6.5
Identities = 32/126 (25%), Positives = 46/126 (36%), Gaps = 7/126 (5%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + ++D+ND+ P F + E A D D N+ TY + +D
Sbjct: 116 VEIEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKTYTLNNNDF- 174
Query: 1091 LPFEISPLTG-----VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ L L V LDRE + + L + A D G D+N
Sbjct: 175 FRLNVKTLKNGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIVQ-DIN 233
Query: 1146 DNSPKF 1151
DN PKF
Sbjct: 234 DNEPKF 239
>UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n=2;
Danio rerio|Rep: UPI00015A41E3 UniRef100 entry - Danio
rerio
Length = 1114
Score = 102 bits (245), Expect = 7e-20
Identities = 171/694 (24%), Positives = 280/694 (40%), Gaps = 100/694 (14%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVLL 677
F VEE +G++T+ L R + V+ L I T++ V D ND +
Sbjct: 71 FTVEEHTGIVTIKILLDRETTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPI-F 129
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNG-TGNVRFLIANQQDVTDD----IAI 732
G P V EN+ +G + T ++ G G V + I + V DD +
Sbjct: 130 NGL--PYNKEVLENT---TVGFVLFTASATDSDFGQAGIVSYKI--DEVVPDDKDMFSIV 182
Query: 733 AEDGTIFTQKPLD-REKRDVYRMTVIAEFNKGVISGAGIYQVT-----IYIEDENDNPPV 786
A G + L+ EK Y++ + A G + G + Q + I ++D D P
Sbjct: 183 AATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGEEVVQSSSAIAFITVKDVPDIDPQ 242
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGV 845
F + + EN+ +GT + ++A D D G N +++ ++F +D NTG+
Sbjct: 243 FLNLPNNAAVEENTGVGTTV---FTVRARDPDTGVNDKITFSIDKTNASDLFRIDTNTGI 299
Query: 846 VKFIGDSLDREKKIMYKLSLVAR--------DTGGL--SSEAELIIMIGDENDNKPEFNQ 895
V + +DRE+ + ++V + + G+ S+ EL I I DENDN PEF +
Sbjct: 300 VS-VNAEIDREELLNISATVVLKIKASETMPNVNGVIASTIGELQISIKDENDNSPEFYE 358
Query: 896 IEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNA 955
E + ++ K+ F +V++ L N + +
Sbjct: 359 CEGEACMK--------------------KDNFEGNVNEHSSTGLAVAN-------LNIKV 391
Query: 956 LDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR- 1014
DLD G N + P K DA V + E V+V + E +
Sbjct: 392 KDLDGGENSTFNLHLDG-----PDK---DAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQ 443
Query: 1015 ---LNISALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ I A+D + +V + + D ND+FP F+K Y V E ++ + AT
Sbjct: 444 IMNVQIIAVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIAT 503
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV-NGE-LDRETEDKYILTVVARDNGXX 1128
DAD +TY + P F + TG + V NG+ LD E Y LT+ A D+G
Sbjct: 504 DADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSG-- 561
Query: 1129 XXXXXXXXXXXXXXDVNDNSPK-----FYAF-----DELLEWKHPEADELSNHNFESVMM 1178
D+NDN+P+ + AF D ++ + + DE N E
Sbjct: 562 -NNTGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDEPKTLNSEVQYR 620
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR-KNQQNLGLPSLSSTAI 1237
I ++T N IG + + N D + + Q +LG PS SS+A
Sbjct: 621 IS-EESTFSSNFTIGLE-SGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAK 678
Query: 1238 LMVTVADVPDEVEMSDKPVFI-SRYYELEIEENV 1270
+ ++V D D + P ++ S YE ++E+V
Sbjct: 679 VNISVGDAND-----NAPRYLDSSPYEFRVKESV 707
Score = 97.9 bits (233), Expect = 2e-18
Identities = 130/486 (26%), Positives = 204/486 (41%), Gaps = 48/486 (9%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
++NVE DANDN P+F + L Y + N VG V+ A D D GQ G+V Y +
Sbjct: 116 YINVE----DANDNIPIF--NGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKID 169
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV--TIE 558
F I TG V++ + + F + ++ Y VV +
Sbjct: 170 EVVP-DDKDMFSIVAATGVVTLVGNLNFTEKSP-FYQIRINASDGGGELYGEEVVQSSSA 227
Query: 559 VTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-NDVSYDLLHGYEE 616
+ T + PDI P F+ P V N G+GT+V +R D ND +
Sbjct: 228 IAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVNDKITFSIDKTNA 287
Query: 617 GVPFAVEERSGVITVVDDLSRYN------RPMYDFEAVALQENAN---LSIVTNATVHVV 667
F ++ +G+++V ++ R + +A N N S + + +
Sbjct: 288 SDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNVNGVIASTIGELQISIK 347
Query: 668 DVNDERGVLLKGAHSPIIF------HVKENSA-GAAIGQIFHTNMSSIYG--NGTGNVRF 718
D ND + + +V E+S+ G A+ + + + + G N T N+
Sbjct: 348 DENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANL-NIKVKDLDGGENSTFNLH- 405
Query: 719 LIANQQD---VTDDIAIAEDGT-IFTQKP--LDREKRDVYRMTVIA-EFNKGVISGAGIY 771
L +D V+ + E + + P +D E + + + +IA + N S A
Sbjct: 406 LDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVDANADFTSTA--- 462
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
VTI++ D NDN P FE Y+ + E+ + GT + I ATDAD Y L
Sbjct: 463 TVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVAT---IIATDADAFDEGKITYRLMP 519
Query: 832 EG-KEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDN 889
E + +F V E TG + GD+LD E Y L+L A D+G + + I I D NDN
Sbjct: 520 ESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGNNTGTTVVEISILDINDN 579
Query: 890 KPEFNQ 895
PE N+
Sbjct: 580 APEMNR 585
Score = 94.3 bits (224), Expect = 2e-17
Identities = 131/503 (26%), Positives = 223/503 (44%), Gaps = 66/503 (13%)
Query: 433 EYYDEQLM--SFVNVEVTLLDANDNNPVFV--PSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
E Y E+++ S +T+ D D +P F+ P+N +++ N VGT + V+A DPD
Sbjct: 215 ELYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNA---AVEENTGVGTTVFTVRARDPD 271
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV------AESPILEGRHALFVEASDQP 542
G N + + + +T+ + F+I+ NTG VSV E + L ++AS+
Sbjct: 272 TGVNDKITFSIDKTN---ASDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETM 328
Query: 543 ANPSERRYS-LAVVTIEVTRGTKGNKPDIPDFMGAP------YEFWVGSNVGIGTSVG-- 593
N + S + + I + + N P+ + G +E V + G +V
Sbjct: 329 PNVNGVIASTIGELQISI-KDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANL 387
Query: 594 QIRVNDAFEQNDVSYDL-LHGYEEGVPFAVEERSG-----VITVVDDLSRYN---RPMYD 644
I+V D + +++L L G ++ F V SG V +V D + + + +
Sbjct: 388 NIKVKDLDGGENSTFNLHLDGPDKDA-FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMN 446
Query: 645 FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
+ +A+ NA+ + T+H+ D ND K + +F EN G + I T+
Sbjct: 447 VQIIAVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCEN--GTIVATIIATD 504
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQK--PLDREKRDVYRMTVIAEFN 761
+ + G R + + + + E GTI+ LD E Y +T+ A F+
Sbjct: 505 -ADAFDEGKITYRLM---PESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQA-FD 559
Query: 762 KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE-- 819
G +G + +++I D NDN P YE F+ EN + K+ I+ATD DE
Sbjct: 560 SGNNTGTTVVEISIL--DINDNAPEMNRDIYEAFVQENE----DFKIQ--IQATDRDEPK 611
Query: 820 GTNALFMYTLFGEG--KEMFDVDENTGVVKFIGDSLDRE-----KKIMYKLSLVARDTG- 871
N+ Y + E F + +G++ GD LDRE + + +L ++A D G
Sbjct: 612 TLNSEVQYRISEESTFSSNFTIGLESGLLTNKGD-LDREAIDISQNGVIQLIVIASDLGT 670
Query: 872 -GLSSEAELIIMIGDENDNKPEF 893
SS A++ I +GD NDN P +
Sbjct: 671 PSRSSSAKVNISVGDANDNAPRY 693
Score = 74.1 bits (174), Expect = 3e-11
Identities = 88/349 (25%), Positives = 142/349 (40%), Gaps = 40/349 (11%)
Query: 84 TVYI--EDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--APIGP----SLTIPLTVP 135
T+YI ED NDN+PIF PY+ V E T G F + G S I VP
Sbjct: 114 TIYINVEDANDNIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKIDEVVP 173
Query: 136 RGLTIFKDIRAFDR----DKPNTPNSDVHYSIVSGNDDGHFAL--ESSHKPVLLLRKVLD 189
+F + A N Y I DG L E + + +
Sbjct: 174 DDKDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGEEVVQSSSAIAFITV 233
Query: 190 YDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGNDRKLFSL 246
D D + Q + + + + + + + D D GV + + + N LF +
Sbjct: 234 KDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVNDKITFSIDKTNASDLFRI 293
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ----LNNPLKTAQARVEIELLDLNDN 302
D+ G + + E+D + N+ A T VL+++AS+ +N + + ++I + D NDN
Sbjct: 294 DTNTGIVSVNAEIDREELLNISA-TVVLKIKASETMPNVNGVIASTIGELQISIKDENDN 352
Query: 303 LPEF---------EVDFYNISIVENLPNGFSV--LQVMATDKDQGENGEFTYQLDDP-KG 350
PEF + D + ++ E+ G +V L + D D GEN F LD P K
Sbjct: 353 SPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGGENSTFNLHLDGPDKD 412
Query: 351 AFSIDPRSGW------LTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
AF + P SG + V++ +D E + +++ A + N T
Sbjct: 413 AFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVDANADFTST 461
Score = 69.7 bits (163), Expect = 6e-10
Identities = 103/389 (26%), Positives = 162/389 (41%), Gaps = 50/389 (12%)
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQND-VSYDLLHGYEEGVP-----FA 621
+IP F G PY V N +G + D+ F Q VSY + +E VP F+
Sbjct: 125 NIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKI----DEVVPDDKDMFS 180
Query: 622 VEERSGVITVVDDLSRYNR-PMYDFEAVALQENANLS----IVTNATVHVVDVNDERGVL 676
+ +GV+T+V +L+ + P Y A L + +++ + + V D +
Sbjct: 181 IVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGEEVVQSSSAIAFITVKDVPDID 240
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI-AED 735
+ + P V+EN+ +G T + G + ++ + +D I
Sbjct: 241 PQFLNLPNNAAVEENTG---VGTTVFTVRARDPDTGVNDKITFSIDKTNASDLFRIDTNT 297
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFN--------KGVISGAGIYQVTIYIEDENDNPPVF 787
G + +DRE+ TV+ + GVI+ I ++ I I+DENDN P F
Sbjct: 298 GIVSVNAEIDREELLNISATVVLKIKASETMPNVNGVIAST-IGELQISIKDENDNSPEF 356
Query: 788 EHA---------TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
+EG + E+S G + NI K D D G N+ F L G K+ F
Sbjct: 357 YECEGEACMKKDNFEGNVNEHSSTGLAVANLNI-KVKDLDGGENSTFNLHLDGPDKDAFR 415
Query: 839 VDENTG-----VVKFIGD--SLDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNK 890
V +G V + D ++D E K + + ++A D +S A + I + D NDN
Sbjct: 416 VSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVDANADFTSTATVTIHLNDTNDNF 475
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTII 919
P F + KV H E NGT TII
Sbjct: 476 PTFEKELYKEKVFEHCE---NGTIVATII 501
Score = 64.9 bits (151), Expect = 2e-08
Identities = 53/161 (32%), Positives = 77/161 (47%), Gaps = 15/161 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D + Y L+ + R LF + G++++ LD E ++ L +Q
Sbjct: 500 IIATDADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWE---VTKSYTLTLQ 556
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A N T VEI +LD+NDN PE D Y + EN F + Q+ ATD+D+ +
Sbjct: 557 AFDSGN--NTGTTVVEISILDINDNAPEMNRDIYEAFVQEN--EDFKI-QIQATDRDEPK 611
Query: 338 --NGEFTYQLDDP---KGAFSIDPRSGWLTVRNQTVLDREA 373
N E Y++ + F+I SG LT N+ LDREA
Sbjct: 612 TLNSEVQYRISEESTFSSNFTIGLESGLLT--NKGDLDREA 650
Score = 64.1 bits (149), Expect = 3e-08
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 13/170 (7%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNG------SLFLEKELDLDAEHNLQANTFVLQ 275
D D G +T L G D+ F + +G + ++ +D E N ++
Sbjct: 393 DLDGGENSTFNLHL-DGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIA 451
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V A N T+ A V I L D NDN P FE + Y + E+ NG V ++ATD D
Sbjct: 452 VDA----NADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADA 507
Query: 336 GENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+ G+ TY+L + + F + ++G + V N LD E S + + A
Sbjct: 508 FDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQA 557
Score = 62.9 bits (146), Expect = 7e-08
Identities = 122/488 (25%), Positives = 196/488 (40%), Gaps = 63/488 (12%)
Query: 445 VEVTLLDANDNNPVF--------VPSNLYEFSMKSNAKVGTVIGK--VKAVDPDLGQNGM 494
+++++ D NDN+P F + + +E ++ ++ G + +K D D G+N
Sbjct: 342 LQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGGENS- 400
Query: 495 VLYDLQRTSNLTITSP----FKINPNTG----TVSVA----ESPILEGRHALFVEASDQP 542
T NL + P F+++P +G TV V ++ E + + V+
Sbjct: 401 -------TFNLHLDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVD 453
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-- 600
AN S A VTI + T N P F Y+ V + GT V I DA
Sbjct: 454 ANADFT--STATVTIHLN-DTNDN---FPTFEKELYKEKVFEHCENGTIVATIIATDADA 507
Query: 601 FEQNDVSYDLLHGYEEGVPFAVEERSGVITVV--DDLSRYNRPMYDFEAVALQENANLSI 658
F++ ++Y L+ + F V E++G I V D L Y A N
Sbjct: 508 FDEGKITYRLMPESIRSL-FGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGNNTG- 565
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
T + ++D+ND + + + V+EN QI T+ + V++
Sbjct: 566 TTVVEISILDINDNAPEMNRDIYEAF---VQENEDFKI--QIQATDRDEPKTLNS-EVQY 619
Query: 719 LIANQQDVTDDIAIAEDGTIFTQK-PLDREKRD-----VYRMTVIAEFNKGVISGAGIYQ 772
I+ + + + I + + T K LDRE D V ++ VIA + G S + +
Sbjct: 620 RISEESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIAS-DLGTPSRSSSAK 678
Query: 773 VTIYIEDENDNPPVF-EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT--L 829
V I + D NDN P + + + YE + E+ K G + + A D F T
Sbjct: 679 VNISVGDANDNAPRYLDSSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFSITDGS 737
Query: 830 FGEG---KEMFDVDENTGVVKFIGDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIGD 885
FG E F + LD E + Y L + A D G S AE+ I++ D
Sbjct: 738 FGSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHIIVED 797
Query: 886 ENDNKPEF 893
ND PEF
Sbjct: 798 VNDTPPEF 805
Score = 58.8 bits (136), Expect = 1e-06
Identities = 119/492 (24%), Positives = 186/492 (37%), Gaps = 68/492 (13%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V + L D NDN P F LY+ + + + GT++ + A D D G + Y L
Sbjct: 460 STATVTIHLNDTNDNFPTF-EKELYKEKVFEHCENGTIVATIIATDADAFDEGKITYRLM 518
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYSLAVVT 556
S I S F ++ TGT+ V L+ + L ++A D N ++++
Sbjct: 519 PES---IRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGNNTGTTVVEISILD 575
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE----QNDVSYDLLH 612
I + P+ YE +V N QI+ D E ++V Y +
Sbjct: 576 I---------NDNAPEMNRDIYEAFVQENEDFKI---QIQATDRDEPKTLNSEVQYRISE 623
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA------NLSIVTNATVHV 666
F + SG++T DL R + + L A + S + V
Sbjct: 624 ESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVNISV 683
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF-HTNMSSIYGN------GTGNVRFL 719
D ND L SP F VKE+ G +G + H + + N G+
Sbjct: 684 GDANDNAPRYLDS--SPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSITDGSFGSF 741
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDRE-KRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
I + + + T+ LD E R Y + V A + + + +V I +E
Sbjct: 742 IIYSEAFSK--GYRGNITVDPSVELDYESNRKEYTLKVQA---SDLGQKSDVAEVHIIVE 796
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------ 832
D ND PP F G I++ + T + IK D D TN +Y L
Sbjct: 797 DVNDTPPEFP----SGMILKVDENTTLPVPVDTIKGKDVD--TNHSLIYELVSTKCQCNG 850
Query: 833 -----GKEMFDVDENTGVVKFIGDSLDREK-KIMYKLSLVA---RDTGGLSSEAELIIMI 883
+E F V+ N ++ +D EK +++ + V + G SSE ++ I
Sbjct: 851 TIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTI 910
Query: 884 G--DENDNKPEF 893
D NDN PEF
Sbjct: 911 NIVDINDNAPEF 922
Score = 54.0 bits (124), Expect = 3e-05
Identities = 45/145 (31%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 991 YFVINERHGHVIVARSLPPES--EFRLN-ISALDGGNLNDNISVRVF--VKDVNDHFPVF 1045
+F + E G V + L E+ F+ +S + L + ++ V+D ND+ P+F
Sbjct: 70 FFTVEEHTGIVTIKILLDRETTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPIF 129
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVL 1102
YN V E VL ATD+DFGQ ++Y I P D D+ F I TGV+
Sbjct: 130 NGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKIDEVVPDDKDM-FSIVAATGVV 188
Query: 1103 SVNGELD-RETEDKYILTVVARDNG 1126
++ G L+ E Y + + A D G
Sbjct: 189 TLVGNLNFTEKSPFYQIRINASDGG 213
Score = 52.4 bits (120), Expect = 9e-05
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 12/134 (8%)
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR--VE 293
I+G + F+++ G + ++ LD + + + T V S N P Q R +
Sbjct: 63 IAGTNAGFFTVEEHTGIVTIKILLDRETTQHFKC-TLV-----STYNAPTLFIQVRKTIY 116
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD----DPK 349
I + D NDN+P F YN ++EN GF + ATD D G+ G +Y++D D K
Sbjct: 117 INVEDANDNIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKIDEVVPDDK 176
Query: 350 GAFSIDPRSGWLTV 363
FSI +G +T+
Sbjct: 177 DMFSIVAATGVVTL 190
Score = 45.2 bits (102), Expect = 0.014
Identities = 39/150 (26%), Positives = 70/150 (46%), Gaps = 16/150 (10%)
Query: 207 RIHKEILFPEPIHAID-QDLGVGATLRYELISGN----------DRKLFSLDSVNGSLFL 255
++ + P P+ I +D+ +L YEL+S + F ++S NG +
Sbjct: 812 KVDENTTLPVPVDTIKGKDVDTNHSLIYELVSTKCQCNGTIGPCPEEWFIVES-NGDIIA 870
Query: 256 EKELDLDAEH-NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV--DFYN 312
E +D E ++ T + +++ + V I ++D+NDN PEF DFY
Sbjct: 871 NTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTINIVDINDNAPEFVFLQDFY- 929
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFT 342
+ ++E + G SV + ATD+D +N + T
Sbjct: 930 VVVIEKVDTGTSVARAYATDRDTADNNKKT 959
Score = 43.6 bits (98), Expect = 0.043
Identities = 44/152 (28%), Positives = 70/152 (46%), Gaps = 11/152 (7%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F++ +G L + +LD +A Q L V AS L P +++ A+V I + D NDN
Sbjct: 631 FTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVNISVGDANDNA 690
Query: 304 PEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGE-NGEFTYQLDDPK-GAFSIDPRS-- 358
P + + Y + E++ G V V A D DQ + N + + D G+F I +
Sbjct: 691 PRYLDSSPYEFRVKESV-KGIYVGPVHAHDADQTDFNNRIFFSITDGSFGSFIIYSEAFS 749
Query: 359 ----GWLTVRNQTVLDREAH-SSLRMKVYAKE 385
G +TV LD E++ +KV A +
Sbjct: 750 KGYRGNITVDPSVELDYESNRKEYTLKVQASD 781
Score = 41.1 bits (92), Expect = 0.23
Identities = 47/168 (27%), Positives = 69/168 (41%), Gaps = 17/168 (10%)
Query: 812 IKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA---R 868
I ATD D+ Y + G F V+E+TG+V I LDRE +K +LV+
Sbjct: 49 IVATDPDDDP---LTYKIAGTNAGFFTVEEHTGIVT-IKILLDRETTQHFKCTLVSTYNA 104
Query: 869 DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFA 928
T + + I + D NDN P FN + N +E N T GF + +
Sbjct: 105 PTLFIQVRKTIYINVEDANDNIPIFNGLPYN------KEVLENTTVGFVLFTASATDS-- 156
Query: 929 LDVDQLGPL-FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
D Q G + + I E +P + + A L G + + S Y
Sbjct: 157 -DFGQAGIVSYKIDEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFY 203
Score = 39.9 bits (89), Expect = 0.53
Identities = 83/330 (25%), Positives = 128/330 (38%), Gaps = 36/330 (10%)
Query: 1066 KVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
K+ ATD D + LTY I ++ F + TG++++ LDRET + T+V+ N
Sbjct: 48 KIVATDPD---DDPLTYKIAGTNAGF-FTVEEHTGIVTIKILLDRETTQHFKCTLVSTYN 103
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAF---DELLEWKHPEADELSNHNFESVM-MIPV 1181
D NDN P F E+LE + +S +
Sbjct: 104 APTLFIQVRKTIYINVEDANDNIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGI 163
Query: 1182 YKATIEENAPIGTTVAKVFA--NDTDFIGNGNGLILYSLPQ-RKNQQN-----LGLPSLS 1233
I+E P + + A +GN N Q R N + G +
Sbjct: 164 VSYKIDEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGEEVVQ 223
Query: 1234 STAIL-MVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKM 1290
S++ + +TV DVPD P F++ +EEN V V V + N K+
Sbjct: 224 SSSAIAFITVKDVPD-----IDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVNDKI 278
Query: 1291 RYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYP 1350
+ I N +D+ F ID G + + DRE V + K S +P++
Sbjct: 279 TFSIDKTNASDL---FRIDTNTGIVSVNAEIDREELLNISATV-VLKIKASETMPNVNGV 334
Query: 1351 VAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+A + E + + IKD NDNSP+F
Sbjct: 335 IASTIGE--------LQISIKDENDNSPEF 356
>UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 841
Score = 101 bits (243), Expect = 1e-19
Identities = 111/461 (24%), Positives = 204/461 (44%), Gaps = 28/461 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + N+ VT+ D +DN P F + + + GT + ++KA D DLGQN + +
Sbjct: 210 LSATANLSVTVTDVDDNCPEFDDDSPIKAIVPGLGIKGTAVAQLKATDKDLGQNAQITFS 269
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
R + + F ++ +TG +S+A + H L V A+ P++ A VT
Sbjct: 270 FSRQISDRAKTLFYMDRHTGLISLAVDVHTDSPEEHMLKVFANGPLCPPAQ-----AQVT 324
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD--LLHGY 614
+ + + ++P I ++ + V + V E D S D L
Sbjct: 325 VYI-QPMVSSEPTIKIRFVTEHK----NQVIMLQENEPPTVLALLELEDTSSDKGTLSLE 379
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
+ +PF++++++G + + +++ + + + + + V V V D
Sbjct: 380 TDSMPFSLKQQAGSYLLSTSKALDFELCGEYDVTVVISDPHGARLHGREVIKVVVQDLND 439
Query: 675 VLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + +KEN+ G + ++ T+ S + G V + I N
Sbjct: 440 NAPKFEQTRYETDIKENNKPGEFLLKVQATDADS---HQFGKVEYRITNGSPFRIQ---E 493
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G I +PLDRE++ Y +TV+A+ + G S V + + D NDNPP F +
Sbjct: 494 ETGVILVTEPLDREQQGTYILTVLAQ-DGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFY 552
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
F+ E+ + + +DAD+G N + K F +D + G+++ G+ +
Sbjct: 553 FFVSESL---PHLSQVGKVTVSDADDGDNGRIVDLRILNDKAPFVIDMSQGMLRSTGE-V 608
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
DREK+ Y+L +VA D G LS+ ++ + + D NDN+P+
Sbjct: 609 DREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDINDNQPQ 649
Score = 88.6 bits (210), Expect = 1e-15
Identities = 109/416 (26%), Positives = 175/416 (42%), Gaps = 53/416 (12%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ QK LDRE +D Y + ++A ++G + + +++ + D +DN P F+ + I+
Sbjct: 182 LIVQKELDRETQDNYFLVLVA-VDRGSMPLSATANLSVTVTDVDDNCPEFDDDSPIKAIV 240
Query: 798 ENSKI-GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDRE 856
I GT + +KATD D G NA ++ F DR
Sbjct: 241 PGLGIKGTAVAQ---LKATDKDLGQNAQITFS-------------------FSRQISDRA 278
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGF 916
K + Y + R TG LI + D + + PE + ++ + + + T
Sbjct: 279 KTLFY----MDRHTG-------LISLAVDVHTDSPEEHMLKVFANGPLCPPAQAQVTVYI 327
Query: 917 T-IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
++ +P K + + ++ EN P T++ L L+ S G + E +S
Sbjct: 328 QPMVSSEPTIKIRFVTEHKNQVIMLQENEP--PTVLALLELEDTSSDKGTLSLETDSM-- 383
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFV 1035
P L A Y + + + L E + + IS G L+ ++V V
Sbjct: 384 --PFSLKQQA---GSYLLSTSK----ALDFELCGEYDVTVVISDPHGARLHGREVIKVVV 434
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI 1095
+D+ND+ P F++T Y +++E L KV ATDAD Q + Y I PF I
Sbjct: 435 QDLNDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRITNGS---PFRI 491
Query: 1096 SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TGV+ V LDRE + YILTV+A+D G D+NDN P F
Sbjct: 492 QEETGVILVTEPLDREQQGTYILTVLAQDGG-DPSQEAFAIVFVNVLDMNDNPPAF 546
Score = 83.0 bits (196), Expect = 6e-14
Identities = 73/261 (27%), Positives = 120/261 (45%), Gaps = 18/261 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V + D NDN P F + YE +K N K G + KV+A D D Q G V Y
Sbjct: 430 IKVVVQDLNDNAPKFEQTR-YETDIKENNKPGEFLLKVQATDADSHQFGKVEY------R 482
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+T SPF+I TG + V E E G + L V A D +PS+ +++ V +
Sbjct: 483 ITNGSPFRIQEETGVILVTEPLDREQQGTYILTVLAQDG-GDPSQEAFAIVFVNV---LD 538
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P P + F+V ++ + VG++ V+DA + ++ L + PF +
Sbjct: 539 MNDNPPAFPT---PHFYFFVSESLPHLSQVGKVTVSDADDGDNGRIVDLRILNDKAPFVI 595
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDER-GVLLKGA 680
+ G++ ++ R + Y+ VA+ + LS TV V D+ND + VLL +
Sbjct: 596 DMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDINDNQPQVLLPSS 655
Query: 681 HSPIIFHVKENSAGAAIGQIF 701
+ + AG+ I +I+
Sbjct: 656 NLSCLTISPATQAGSMITKIY 676
Score = 78.6 bits (185), Expect = 1e-12
Identities = 67/215 (31%), Positives = 94/215 (43%), Gaps = 22/215 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN G ++K+ A D DS G++ Y + P F I E G
Sbjct: 453 IKENNKPGEFLLKVQATDADSHQFGKVEYRITNG---SP-------------FRIQEETG 496
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
++V L E + + L + A DGG+ + VFV D+ND+ P F + F V
Sbjct: 497 VILVTEPLDREQQGTYILTVLAQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFFVS 556
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ +GKV +DAD G N + +D PF I G+L GE+DRE +D+
Sbjct: 557 ESLPHLSQVGKVTVSDADDGDNGRIVDLRILNDK-APFVIDMSQGMLRSTGEVDREKQDR 615
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y L VVA D G D+NDN P+
Sbjct: 616 YELLVVAVDGG-SPVLSTTVKMTVFVEDINDNQPQ 649
Score = 74.1 bits (174), Expect = 3e-11
Identities = 57/163 (34%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEF-NKGVISG-AGIYQVTIYIEDENDNPPVFEHATYE 793
G +FT+ LDRE F N V+S + + I + D NDN PVFE
Sbjct: 71 GDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVNDINDNAPVFERNEIP 130
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I E++ IGT +D+ +A D D N L Y L G E+ G+ + L
Sbjct: 131 LRIPEDTSIGTTFLLDD--QAQDKDTANNGLIHYHLEGSNGFFGIRQEDYGLELIVQKEL 188
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
DRE + Y L LVA D G LS+ A L + + D +DN PEF+
Sbjct: 189 DRETQDNYFLVLVAVDRGSMPLSATANLSVTVTDVDDNCPEFD 231
Score = 65.7 bits (153), Expect = 9e-09
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D + Y + +G+ F + G + + + LD + Q T++L V
Sbjct: 466 VQATDADSHQFGKVEYRITNGSP---FRIQEETGVILVTEPLDRE-----QQGTYILTVL 517
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + A A V + +LD+NDN P F + + E+LP+ V +V +D D G+
Sbjct: 518 AQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQVGKVTVSDADDGD 577
Query: 338 NGEFT-YQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
NG ++ + K F ID G L R+ +DRE + V A + V+ T
Sbjct: 578 NGRIVDLRILNDKAPFVIDMSQGML--RSTGEVDREKQDRYELLVVAVDGGSPVLST 632
Score = 59.3 bits (137), Expect = 8e-07
Identities = 54/198 (27%), Positives = 92/198 (46%), Gaps = 23/198 (11%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F + E++P + + K+ D D G NG+I + L K FVI+
Sbjct: 553 FFVSESLPHLSQVGKVTVSDADDGDNGRI--------------VDLRILNDKAPFVIDMS 598
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + + E + + L + A+DGG+ L+ + + VFV+D+ND+ P N +
Sbjct: 599 QGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDINDNQPQVLLPSSNLS 658
Query: 1054 ---VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL--PFEISPLTGVLSVNGEL 1108
+ A ++ K+ A D D G N+++TY I S+ L PF+I +G +++ L
Sbjct: 659 CLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSPFQIDQHSGNITLVQHL 718
Query: 1109 DRETEDKYILTVVARDNG 1126
E + L +V RD G
Sbjct: 719 RGEDYGMHHLFIVVRDGG 736
Score = 58.8 bits (136), Expect = 1e-06
Identities = 45/150 (30%), Positives = 73/150 (48%), Gaps = 11/150 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D+D + Y L N + L ++KELD + Q N F++ V
Sbjct: 149 AQDKDTANNGLIHYHLEGSNGFFGIRQEDYGLELIVQKELDRET----QDNYFLVLVAVD 204
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVMATDKDQGEN 338
+ + PL +A A + + + D++DN PEF+ D +IV L G +V Q+ ATDKD G+N
Sbjct: 205 RGSMPL-SATANLSVTVTDVDDNCPEFDDDSPIKAIVPGLGIKGTAVAQLKATDKDLGQN 263
Query: 339 GEFTYQL-----DDPKGAFSIDPRSGWLTV 363
+ T+ D K F +D +G +++
Sbjct: 264 AQITFSFSRQISDRAKTLFYMDRHTGLISL 293
Score = 55.6 bits (128), Expect = 1e-05
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 2/126 (1%)
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
D + + + V D+ND+ PVF++ + E+ L A D D N + Y ++
Sbjct: 106 DVVPMVIVVNDINDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLE 165
Query: 1086 PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
S+ L V ELDRET+D Y L +VA D G DV+
Sbjct: 166 GSNGFFGIRQEDYGLELIVQKELDRETQDNYFLVLVAVDRG-SMPLSATANLSVTVTDVD 224
Query: 1146 DNSPKF 1151
DN P+F
Sbjct: 225 DNCPEF 230
Score = 54.0 bits (124), Expect = 3e-05
Identities = 104/482 (21%), Positives = 185/482 (38%), Gaps = 61/482 (12%)
Query: 930 DVDQLGPLFLIPENIPI-GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEV 988
+ D P+ I + I GT + +L A D D G N QI + F+ ++ +D
Sbjct: 229 EFDDDSPIKAIVPGLGIKGTAVAQLKATDKDLGQNAQITFSFSRQI--------SD--RA 278
Query: 989 KRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLND--NISVRVFVKDVNDHFPVFK 1046
K F ++ G + +A + +S + G L V V+++ + P K
Sbjct: 279 KTLFYMDRHTGLISLAVDVHTDSPEEHMLKVFANGPLCPPAQAQVTVYIQPMVSSEPTIK 338
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG--VLSV 1104
+ + + + + ++ + +PF + G +LS
Sbjct: 339 IRFVTEHKNQVIMLQENEPPTVLALLELEDTSSDKGTLSLETDSMPFSLKQQAGSYLLST 398
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
+ LD E +Y +TVV D D+NDN+PKF E E
Sbjct: 399 SKALDFELCGEYDVTVVISDP-HGARLHGREVIKVVVQDLNDNAPKF-------EQTRYE 450
Query: 1165 ADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ 1224
D + +N ++ V +AT ++ G ++ I G+IL + P + Q
Sbjct: 451 TD-IKENNKPGEFLLKV-QATDADSHQFGKVEYRITNGSPFRIQEETGVILVTEPLDREQ 508
Query: 1225 QNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV 1274
Q G PS + AI+ V V D+ D + P F + ++ + E++
Sbjct: 509 QGTYILTVLAQDGGDPSQEAFAIVFVNVLDMND-----NPPAFPTPHFYFFVSESLPHLS 563
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR 1334
++ + +++ + R I++ + + FVID G L DRE +D YE++V
Sbjct: 564 QVGKVTVSDADDGDNGR--IVDLRILNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLV- 620
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK--FTNGNRPLVTAIP 1392
VA D + VK+ V ++D+NDN P+ + N +T P
Sbjct: 621 ----------------VAVDGGSPVLSTTVKMTVFVEDINDNQPQVLLPSSNLSCLTISP 664
Query: 1393 TT 1394
T
Sbjct: 665 AT 666
Score = 52.8 bits (121), Expect = 7e-05
Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 6/146 (4%)
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
D FSL GS L LD E + + V S + + +++ + DL
Sbjct: 381 DSMPFSLKQQAGSYLLSTSKALDFE---LCGEYDVTVVISDPHGARLHGREVIKVVVQDL 437
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSG 359
NDN P+FE Y I EN G +L+V ATD D + G+ Y++ + F I +G
Sbjct: 438 NDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRITN-GSPFRIQEETG 496
Query: 360 WLTVRNQTVLDREAHSSLRMKVYAKE 385
+ V LDRE + + V A++
Sbjct: 497 VILVTEP--LDREQQGTYILTVLAQD 520
Score = 52.0 bits (119), Expect = 1e-04
Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
L + V + V + D NDN P V +PS NL ++ + G++I K+ A+D D G N +
Sbjct: 630 LSTTVKMTVFVEDINDNQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDIT 689
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASD 540
Y + S + SPF+I+ ++G +++ + E G H LF+ D
Sbjct: 690 YQI-IASEPALQSPFQIDQHSGNITLVQHLRGEDYGMHHLFIVVRD 734
Score = 49.2 bits (112), Expect = 9e-04
Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 12/132 (9%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
ND+ F +D G L E+D + + + + L V A +P+ + ++ + + D
Sbjct: 588 NDKAPFVIDMSQGMLRSTGEVDREKQ-----DRYELLVVAVDGGSPVLSTTVKMTVFVED 642
Query: 299 LNDNLPEFEVDFYNISIVENLPN---GFSVLQVMATDKDQGENGEFTYQL--DDP--KGA 351
+NDN P+ + N+S + P G + ++ A D+D G N + TYQ+ +P +
Sbjct: 643 INDNQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSP 702
Query: 352 FSIDPRSGWLTV 363
F ID SG +T+
Sbjct: 703 FQIDQHSGNITL 714
Score = 44.4 bits (100), Expect = 0.024
Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 3/138 (2%)
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+ + +D + G LF + LD + + + + ++ L + + D+
Sbjct: 60 NERYIRVDEITGDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVN--DI 117
Query: 300 NDNLPEFEVDFYNISIVENLPNGFS-VLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
NDN P FE + + I E+ G + +L A DKD NG Y L+ G F I
Sbjct: 118 NDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLEGSNGFFGIRQED 177
Query: 359 GWLTVRNQTVLDREAHSS 376
L + Q LDRE +
Sbjct: 178 YGLELIVQKELDRETQDN 195
Score = 44.0 bits (99), Expect = 0.032
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 14/205 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D +F V V +LD NDN P F + Y F +S + V GKV D D G NG +
Sbjct: 523 DPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQV-GKVTVSDADDGDNGRI 581
Query: 496 LYDLQRTSNLTITSPFKINPNTGTV-SVAE-SPILEGRHALFVEASDQPANPSERRYSLA 553
+ DL+ L +PF I+ + G + S E + R+ L V A D + +
Sbjct: 582 V-DLR---ILNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMT 637
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL 611
V ++ N+P + + G+ + +I D+ +D++Y ++
Sbjct: 638 VFVEDI----NDNQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQII 693
Query: 612 HGYEE-GVPFAVEERSGVITVVDDL 635
PF +++ SG IT+V L
Sbjct: 694 ASEPALQSPFQIDQHSGNITLVQHL 718
>UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadherin
gamma B5, partial; n=2; Gallus gallus|Rep: PREDICTED:
similar to protocadherin gamma B5, partial - Gallus
gallus
Length = 850
Score = 101 bits (243), Expect = 1e-19
Identities = 111/462 (24%), Positives = 189/462 (40%), Gaps = 29/462 (6%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ +VEV + D NDN+P F + L + + G A DPD+G N ++ Y L
Sbjct: 116 LNVFHVEVAIHDINDNSPAFSKAVL-DLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQL 174
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
S+ ++ V E + + + F + + + V
Sbjct: 175 TEDSSFSLAMKVSKGGKQQPELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNV 234
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEG 617
+ + P F Y+ + N+ +G+ V Q+R DA ++ VSY E
Sbjct: 235 SDAND----NAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSY-FFGNVPES 289
Query: 618 VP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
V F+++ SG + L R Y F + ++ L+ + ++D ND
Sbjct: 290 VRSLFSIDAESGEVRTAGPLDFEERSKYSF-GLEGRDGGGLTGHCEVQIDIIDENDNAPE 348
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ + S V E++ + + NG VR ++ D I +
Sbjct: 349 ITTLSLSS---RVPEDAPPGTVVALLKVRDRDSGENG--QVRCELSG--DTPLQIVASSG 401
Query: 736 GT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G+ + T LDRE+ +R+TVIA ++G + + + + + D NDN PVFE A Y
Sbjct: 402 GSYKVVTAGALDRERASEHRVTVIAT-DRGSPALSSRADLVLEVSDVNDNAPVFEEAAYS 460
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGD 851
++ EN+ G + + A DAD G N Y L G G + V TG + +
Sbjct: 461 AYVPENNAAGEPVLR---VSARDADAGANGRVSYALAGGGADAAFVSVRAETGEL-YAQR 516
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
S D E+ + + + ARD G S+ A + + + D NDN P
Sbjct: 517 SFDYERCREFSVEVRARDGGTPARSATATVRVFVLDRNDNAP 558
Score = 93.9 bits (223), Expect = 3e-17
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 10/166 (6%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
++ LDREK+ ++M + A + G + +G + + + D NDN PVF Y+ + EN
Sbjct: 199 ERALDREKQSSFQMVLTAT-DGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMRENL 257
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDSLDRE 856
+G+ + ++A DAD G+N Y FG E +F +D +G V+ G LD E
Sbjct: 258 PVGSLVLQ---VRAADADAGSNGRVSY-FFGNVPESVRSLFSIDAESGEVRTAGP-LDFE 312
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ Y L RD GGL+ E+ I I DENDN PE + +S+V
Sbjct: 313 ERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTLSLSSRV 358
Score = 80.6 bits (190), Expect = 3e-13
Identities = 68/237 (28%), Positives = 105/237 (44%), Gaps = 19/237 (8%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I++ +N A ++ L +PE+ P GT + L D DSG NGQ+R E + + P
Sbjct: 337 IDIIDENDNAPEITTLSLSSRVPEDAPPGTVVALLKVRDRDSGENGQVRCELSGDT--PL 394
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVF 1034
+++ K V+ A +L E SE R+ + A D G+ L+ + +
Sbjct: 395 QIVASSGGSYK-----------VVTAGALDRERASEHRVTVIATDRGSPALSSRADLVLE 443
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF- 1093
V DVND+ PVF++ Y+ V E + +V A DAD G N ++Y + D F
Sbjct: 444 VSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAGGGADAAFV 503
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ TG L D E ++ + V ARD G D NDN+P+
Sbjct: 504 SVRAETGELYAQRSFDYERCREFSVEVRARDGG-TPARSATATVRVFVLDRNDNAPR 559
Score = 78.2 bits (184), Expect = 2e-12
Identities = 67/237 (28%), Positives = 106/237 (44%), Gaps = 17/237 (7%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN- 722
V+V D ND V K A+ ++EN ++ + + G V + N
Sbjct: 232 VNVSDANDNAPVFNKNAYDA---QMRENLPVGSL--VLQVRAADADAGSNGRVSYFFGNV 286
Query: 723 QQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ V +I AE G + T PLD E+R Y + G+ G +V I I DEN
Sbjct: 287 PESVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGGGL---TGHCEVQIDIIDEN 343
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DN P + + E++ GT + + +K D D G N L G+ V
Sbjct: 344 DNAPEITTLSLSSRVPEDAPPGTVVAL---LKVRDRDSGENGQVRCELSGDTPLQI-VAS 399
Query: 842 NTGVVKFI-GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ G K + +LDRE+ ++++++A D G LSS A+L++ + D NDN P F +
Sbjct: 400 SGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRADLVLEVSDVNDNAPVFEE 456
Score = 77.8 bits (183), Expect = 2e-12
Identities = 61/213 (28%), Positives = 94/213 (44%), Gaps = 16/213 (7%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN+P+G+ ++++ A D D+G NG++ Y F + +P S V+ F I+ G V
Sbjct: 255 ENLPVGSLVLQVRAADADAGSNGRVSYFFGN---VPES--------VRSLFSIDAESGEV 303
Query: 1002 IVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
A L E S++ + DGG L + V++ + D ND+ P + V E
Sbjct: 304 RTAGPLDFEERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAP 363
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN-GELDRETEDKYIL 1118
V+ + D D G+N + + DT L S V G LDRE ++ +
Sbjct: 364 PGTVVALLKVRDRDSGENGQVRCELS-GDTPLQIVASSGGSYKVVTAGALDRERASEHRV 422
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
TV+A D G DVNDN+P F
Sbjct: 423 TVIATDRG-SPALSSRADLVLEVSDVNDNAPVF 454
Score = 74.5 bits (175), Expect = 2e-11
Identities = 108/403 (26%), Positives = 167/403 (41%), Gaps = 51/403 (12%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SE 1012
A D D G N + Y+ + S S A++V + ++ +++ R+L E S
Sbjct: 159 AQDPDVGSNSLLTYQLTED-----SSFSL-AMKVSKG---GKQQPELVLERALDREKQSS 209
Query: 1013 FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
F++ ++A DGG+ + ++ +RV V D ND+ PVF K Y+ + E ++ +V A
Sbjct: 210 FQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMRENLPVGSLVLQVRAA 269
Query: 1071 DADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
DAD G N ++YF P F I +G + G LD E KY + RD G
Sbjct: 270 DADAGSNGRVSYFFGNVPESVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGG-- 327
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
D NDN+P+ L + PE V ++ V E
Sbjct: 328 -GLTGHCEVQIDIIDENDNAPEITTLS--LSSRVPEDAPPGT----VVALLKVRDRDSGE 380
Query: 1189 NAPI-----GTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ--------NLGLPSLSST 1235
N + G T ++ A+ G+ + +L + + + + G P+LSS
Sbjct: 381 NGQVRCELSGDTPLQIVASSG---GSYKVVTAGALDRERASEHRVTVIATDRGSPALSSR 437
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKMRYY 1293
A L++ V+DV D + PVF Y + EN PV VS + N ++ Y
Sbjct: 438 ADLVLEVSDVND-----NAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVS-Y 491
Query: 1294 ILNENDTDIRRTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
L D FV + G LY RS D E + V VRA
Sbjct: 492 ALAGGGAD--AAFVSVRAETGELYAQRSFDYERCREFSVEVRA 532
Score = 70.5 bits (165), Expect = 3e-10
Identities = 53/166 (31%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
FP + A D D+G + L Y+L + L S G E L+ + Q++ F
Sbjct: 154 FPLEV-AQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGKQQPELVLERALDREKQSS-FQ 211
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ + A+ + K+ + + + D NDN P F + Y+ + ENLP G VLQV A D
Sbjct: 212 MVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADA 271
Query: 334 DQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
D G NG +Y + + FSID SG VR LD E S
Sbjct: 272 DAGSNGRVSYFFGNVPESVRSLFSIDAESG--EVRTAGPLDFEERS 315
Score = 63.7 bits (148), Expect = 4e-08
Identities = 47/176 (26%), Positives = 81/176 (46%), Gaps = 9/176 (5%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G ++ + LDRE+ + F V + ++ V + I D NDN P F A +
Sbjct: 82 ENGNLYVSERLDREELCRESESCAVSFEAVVQNPLNVFHVEVAIHDINDNSPAFSKAVLD 141
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK----FI 849
I E + G ++ A D D G+N+L Y L + + + G + +
Sbjct: 142 LEIGEWTIPGARFPLE---VAQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGKQQPELVL 198
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+LDREK+ +++ L A D G S + + + D NDN P FN+ ++++R
Sbjct: 199 ERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMR 254
Score = 58.8 bits (136), Expect = 1e-06
Identities = 75/282 (26%), Positives = 117/282 (41%), Gaps = 27/282 (9%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPL--- 132
S + + V + D NDN P+F Y + E P G A G + +
Sbjct: 225 SGSVHIRVNVSDANDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFFG 284
Query: 133 TVPRGLTIFKDIRAFDRDKPNTPNSDVH----YSI-VSGNDDGHFALESSHKPVLLLRKV 187
VP + I A + D YS + G D G + H V ++
Sbjct: 285 NVPESVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGGGL---TGHCEV----QI 337
Query: 188 LDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGNDRKL 243
D D ++ ++ R+ ++ P + A+ D+D G +R EL SG D L
Sbjct: 338 DIIDENDNAPEITTLSLSSRVPEDAP-PGTVVALLKVRDRDSGENGQVRCEL-SG-DTPL 394
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
+ S GS + LD E +A+ + V A+ +P +++A + +E+ D+NDN
Sbjct: 395 QIVASSGGSYKVVTAGALDRE---RASEHRVTVIATDRGSPALSSRADLVLEVSDVNDNA 451
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
P FE Y+ + EN G VL+V A D D G NG +Y L
Sbjct: 452 PVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYAL 493
Score = 57.6 bits (133), Expect = 2e-06
Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 9/181 (4%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + Y + + R LFS+D+ +G + LD + +F L+
Sbjct: 266 VRAADADAGSNGRVSYFFGNVPESVRSLFSIDAESGEVRTAGPLDFEERSKY---SFGLE 322
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ + T V+I+++D NDN PE + + E+ P G V + D+D
Sbjct: 323 GR----DGGGLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAPPGTVVALLKVRDRDS 378
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFA 395
GENG+ +L + G V LDRE S R+ V A + + + A
Sbjct: 379 GENGQVRCELSGDTPLQIVASSGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRA 438
Query: 396 D 396
D
Sbjct: 439 D 439
Score = 52.0 bits (119), Expect = 1e-04
Identities = 53/189 (28%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Query: 208 IHKEILFPEPIHAIDQDLGVG-ATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEH 265
I +E+ + + +DLG+ A L + + KL F++ NG+L++ + LD + E
Sbjct: 39 IPEELAKGSLVGPLARDLGLSPAELPARQLRLSSEKLYFAVSGENGNLYVSERLDRE-EL 97
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE-NLPNGFS 324
++ + + +A + NPL VE+ + D+NDN P F ++ I E +P
Sbjct: 98 CRESESCAVSFEAV-VQNPLNVFH--VEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARF 154
Query: 325 VLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWLTVRN---QTVLDREAHSSLRMK 380
L+V A D D G N TYQL +D + ++ G + LDRE SS +M
Sbjct: 155 PLEV-AQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGKQQPELVLERALDREKQSSFQMV 213
Query: 381 VYAKETNPS 389
+ A + S
Sbjct: 214 LTATDGGDS 222
Score = 50.8 bits (116), Expect = 3e-04
Identities = 64/248 (25%), Positives = 96/248 (38%), Gaps = 41/248 (16%)
Query: 976 IPPSKLSADALEV---KRYFVINERHGHVIVARSLPPESEFR------LNISALDGGNLN 1026
+ P++L A L + K YF ++ +G++ V+ L E R ++ A+ LN
Sbjct: 58 LSPAELPARQLRLSSEKLYFAVSGENGNLYVSERLDREELCRESESCAVSFEAVVQNPLN 117
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQ 1085
V V + D+ND+ P F K + + E A D D G N+ LTY +
Sbjct: 118 V-FHVEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTE 176
Query: 1086 PSDTDLPFEIS---PLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
S L ++S L + LDRE + + + + A D G
Sbjct: 177 DSSFSLAMKVSKGGKQQPELVLERALDREKQSSFQMVLTATDGG-DSAKSGSVHIRVNVS 235
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
D NDN+P F N N Y A + EN P+G+ V +V A
Sbjct: 236 DANDNAPVF------------------NKN--------AYDAQMRENLPVGSLVLQVRAA 269
Query: 1203 DTDFIGNG 1210
D D NG
Sbjct: 270 DADAGSNG 277
Score = 50.4 bits (115), Expect = 4e-04
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 20/157 (12%)
Query: 218 IHAIDQDLGVGATLRYELISGN-DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G + Y L G D S+ + G L+ ++ D + + F ++V
Sbjct: 476 VSARDADAGANGRVSYALAGGGADAAFVSVRAETGELYAQRSFDYE-----RCREFSVEV 530
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEF--------EVDFYNISIVENLPN----GFS 324
+A P ++A A V + +LD NDN P E E +P G+
Sbjct: 531 RARDGGTPARSATATVRVFVLDRNDNAPRVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYL 590
Query: 325 VLQVMATDKDQGENGEFTYQ-LDDPKGA-FSIDPRSG 359
V +V+A D D G N +Y+ L P+ A F ++ RSG
Sbjct: 591 VAKVVAVDADAGRNAWLSYELLQAPEPALFRVEARSG 627
Score = 46.8 bits (106), Expect = 0.005
Identities = 53/201 (26%), Positives = 83/201 (41%), Gaps = 32/201 (15%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++EV N A ++ +PEN G +++++A D D+G NG++ Y
Sbjct: 441 VLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAGG---- 496
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
ADA V + G + RS E EF + + A DGG + +VRV
Sbjct: 497 ----GADAAFVS----VRAETGELYAQRSFDYERCREFSVEVRARDGGTPARSATATVRV 548
Query: 1034 FVKDVNDHFPVFKKTWYNFN--------------VEEAQYTRRVLGKVDATDADFGQNAN 1079
FV D ND+ P + W V + ++ KV A DAD G+NA
Sbjct: 549 FVLDRNDNAP--RVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYLVAKVVAVDADAGRNAW 606
Query: 1080 LTYFIQPSDTDLPFEISPLTG 1100
L+Y + + F + +G
Sbjct: 607 LSYELLQAPEPALFRVEARSG 627
Score = 45.6 bits (103), Expect = 0.011
Identities = 48/191 (25%), Positives = 76/191 (39%), Gaps = 11/191 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V++ ++D NDN P +L + +A GTV+ +K D D G+NG V +
Sbjct: 329 LTGHCEVQIDIIDENDNAPEITTLSL-SSRVPEDAPPGTVVALLKVRDRDSGENGQVRCE 387
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L + L I + + T + H + V A+D+ + R L + +
Sbjct: 388 LSGDTPLQIVASSGGSYKVVTAGALDRE-RASEHRVTVIATDRGSPALSSRADLVLEVSD 446
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYEE 616
V + P F A Y +V N G V ++ R DA VSY L G +
Sbjct: 447 V-------NDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAGGGAD 499
Query: 617 GVPFAVEERSG 627
+V +G
Sbjct: 500 AAFVSVRAETG 510
>UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204;
Mammalia|Rep: Protocadherin alpha 8 precursor - Homo
sapiens (Human)
Length = 950
Score = 101 bits (243), Expect = 1e-19
Identities = 137/508 (26%), Positives = 202/508 (39%), Gaps = 88/508 (17%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++G +F +DRE+ V ++ V + ++D NDNPPVF +
Sbjct: 80 QNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKDQK 139
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
F+ E+ + ++ A+DAD G N++ Y L + F +D N S
Sbjct: 140 LFVSESRMPDSRFPLEG---ASDADVGANSVLTYRL--SSHDYFMLDVN---------SK 185
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+ E K++ LV R + + + + KPE L GT
Sbjct: 186 NDENKLV---ELVLRKSLDREDAPAHHLFLTATDGGKPE-----------------LTGT 225
Query: 914 AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
++ V N A +Q I EN GTT+IKLNA D D G NG I Y FNS
Sbjct: 226 VQL-LVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSL 284
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNI 1029
V V +F I+ G +++ +L E E +++ I A D G+ + +
Sbjct: 285 V----------ETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHC 334
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V + D ND+ P T + V E V+ + D D G N +T + P
Sbjct: 335 TVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMP--- 391
Query: 1090 DLPFE-ISPLTGVLS--VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+PF+ +S S ++ LDRE Y L V ARD G DVND
Sbjct: 392 HVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG-SPSLWATASLSVEVADVND 450
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N+P F PE Y ++EN P G + V A D D
Sbjct: 451 NAPAF---------AQPE-----------------YTVFVKENNPPGCHIFTVSARDAD- 483
Query: 1207 IGNGNGLILYSLPQRKNQQNLGLPSLSS 1234
N L+ YSL +R+ +G SLSS
Sbjct: 484 -AQENALVSYSLVERR----VGERSLSS 506
Score = 90.6 bits (215), Expect = 3e-16
Identities = 99/407 (24%), Positives = 168/407 (41%), Gaps = 31/407 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V + VT+LD NDN P F S YE + NA GT + K+ A DPD G NG + Y
Sbjct: 221 ELTGTVQLLVTVLDVNDNAPTFEQSE-YEVRIFENADNGTTVIKLNASDPDEGANGAISY 279
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLAVV 555
+ F I+ NTG + + + E + + ++A+D+ P ++ V
Sbjct: 280 SFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVR 339
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++ ++P+ V + GT + I VND + + +
Sbjct: 340 ILD-------KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDL--DSGANGQVTCSLM 390
Query: 616 EGVPF-AVEERSGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
VPF V ++V D L R Y+ A + +L + +V V DVND
Sbjct: 391 PHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVND 450
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQDVT 727
+ ++ +F VKEN+ IF + V + + ++ ++
Sbjct: 451 NAPAFAQPEYT--VF-VKENNPPGC--HIFTVSARDADAQENALVSYSLVERRVGERSLS 505
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
I++ E G ++ +PLD E+ ++ + V A + GV + +++ DENDN P
Sbjct: 506 SYISVHTESGKVYALQPLDHEELELLQFQVSAR-DAGVPPLGSNVTLQVFVLDENDNAPA 564
Query: 787 FEHATYEGFIMENSK-IGTEIKMDNI---IKATDADEGTNALFMYTL 829
G SK + + ++ ++A DAD G NA Y L
Sbjct: 565 LLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
Score = 79.8 bits (188), Expect = 5e-13
Identities = 112/477 (23%), Positives = 189/477 (39%), Gaps = 34/477 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E ++ + +V+V + D NDN PVF + F +S + A D D+G
Sbjct: 105 HLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSESRMP-DSRFPLEGASDADVG 163
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSE 547
N ++ Y L + K + N V + H LF+ A+D
Sbjct: 164 ANSVLTYRLSSHDYFMLDVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELT 223
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
L V ++V + P F + YE + N GT+V ++ +D E
Sbjct: 224 GTVQLLVTVLDV-------NDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGA 276
Query: 606 VSYDLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
+SY E V F+++ +G I + +L +Y + + + + + T
Sbjct: 277 ISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKI-LIDATDKGHPPMAGHCT 335
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V +V + D+ + + A + + V+E++ G I I +++ + G V +
Sbjct: 336 V-LVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALI---SVNDLDSGANGQVTCSLMP 391
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
++ LDRE+ Y + V A + G S +++ + D ND
Sbjct: 392 HVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR-DGGSPSLWATASLSVEVADVND 450
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEG--KEM 836
N P F Y F+ EN+ G I + A DAD NAL Y+L GE
Sbjct: 451 NAPAFAQPEYTVFVKENNPPGCHI---FTVSARDADAQENALVSYSLVERRVGERSLSSY 507
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
V +G V + LD E+ + + + ARD G L S L + + DENDN P
Sbjct: 508 ISVHTESGKV-YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAP 563
Score = 70.1 bits (164), Expect = 4e-10
Identities = 50/163 (30%), Positives = 78/163 (47%), Gaps = 16/163 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS-----LFLEKELDLDAEHNLQANTFVL 274
A D D+G + L Y L S +D + ++S N L L K LD + A L
Sbjct: 157 ASDADVGANSVLTYRL-SSHDYFMLDVNSKNDENKLVELVLRKSLDRE-----DAPAHHL 210
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A+ P T ++ + +LD+NDN P FE Y + I EN NG +V+++ A+D D
Sbjct: 211 FLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPD 270
Query: 335 QGENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDRE 372
+G NG +Y + FSID +G + +R ++E
Sbjct: 271 EGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQE 313
Score = 65.3 bits (152), Expect = 1e-08
Identities = 65/237 (27%), Positives = 103/237 (43%), Gaps = 10/237 (4%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+DVND + + IF +N G + ++ ++ NG + F +
Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADN--GTTVIKLNASDPDE-GANGAISYSFNSLVE 286
Query: 724 QDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
V D +I + G I + LD E+ ++Y++ + A +KG AG V + I D+ND
Sbjct: 287 TMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDAT-DKGHPPMAGHCTVLVRILDKND 345
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
N P + + E+++ GT I + I D D G N +L
Sbjct: 346 NVPEIALTSLSLPVREDAQFGTVIAL---ISVNDLDSGANGQVTCSLMPHVPFKLVSTFK 402
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIE 897
+ +LDRE+ Y+L + ARD G S + A L + + D NDN P F Q E
Sbjct: 403 NYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPE 459
Score = 64.9 bits (151), Expect = 2e-08
Identities = 63/221 (28%), Positives = 94/221 (42%), Gaps = 21/221 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV N A Q + EN P G I ++A D D+ N + Y E +
Sbjct: 443 VEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL-VERRVGE 501
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG--NLNDNISVRVF 1034
LS+ Y ++ G V + L E + +SA D G L N++++VF
Sbjct: 502 RSLSS-------YISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
Query: 1035 VKDVNDHFPVFKKTWYNFN-------VEEAQYTRRVLGKVDATDADFGQNANLTYFIQP- 1086
V D ND+ P + V + V+ KV A DAD G NA L+Y +QP
Sbjct: 555 VLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPA 614
Query: 1087 -SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
S +PF + TG +S LD ++ L V+ +D+G
Sbjct: 615 ASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHG 655
Score = 60.9 bits (141), Expect = 3e-07
Identities = 67/277 (24%), Positives = 113/277 (40%), Gaps = 25/277 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y S + + FS+D G + + LD + E N + +
Sbjct: 264 LNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQE-----NLYKI 318
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A+ +P V + +LD NDN+PE + ++ + E+ G + + D D
Sbjct: 319 LIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLD 378
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G NG+ T L + + ++ + LDRE S+ + V A++ +PS+ T
Sbjct: 379 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWAT 438
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
+ S +A + NAP + P+ EN + V DA
Sbjct: 439 ASLSVEVA-----DVNDNAP----AFAQPEYTVFVKEN----NPPGCHIFTVSARDADAQ 485
Query: 454 DNNPV---FVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
+N V V + E S+ S V T GKV A+ P
Sbjct: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQP 522
Score = 59.7 bits (138), Expect = 6e-07
Identities = 70/293 (23%), Positives = 119/293 (40%), Gaps = 24/293 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-- 124
L G +++ + + V + DVNDN P F + Y V + E G +
Sbjct: 212 LTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDE 271
Query: 125 GPSLTIPLTVPRGL-TIFKDIRAFDRDKPNT--------PNSDVHYSIVSGNDDGHFALE 175
G + I + + T+ D + DR+ +++ ++ D GH +
Sbjct: 272 GANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPM- 330
Query: 176 SSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLR 232
+ H VL+ ++LD + D ++ + + + ++ F I I D D G +
Sbjct: 331 AGHCTVLV--RILDKN--DNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVT 386
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
L+ KL S SL L+ LD + + + + L V A +P A A +
Sbjct: 387 CSLMPHVPFKLVSTFKNYYSLVLDSALDRE-----RVSAYELVVTARDGGSPSLWATASL 441
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+E+ D+NDN P F Y + + EN P G + V A D D EN +Y L
Sbjct: 442 SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
Score = 54.0 bits (124), Expect = 3e-05
Identities = 67/241 (27%), Positives = 101/241 (41%), Gaps = 23/241 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++ + KN ++ + E+ GT I ++ DLDSG NGQ+ V
Sbjct: 337 LVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHV--- 393
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
P KL + K Y+ + ++ +L E S + L ++A DGG+ L S+ V
Sbjct: 394 PFKLVST---FKNYYSL-------VLDSALDRERVSAYELVVTARDGGSPSLWATASLSV 443
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTD 1090
V DVND+ P F + Y V+E + V A DAD +NA ++Y + + +
Sbjct: 444 EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERS 503
Query: 1091 LPFEISPLT--GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
L IS T G + LD E + V ARD G D NDN+
Sbjct: 504 LSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAG-VPPLGSNVTLQVFVLDENDNA 562
Query: 1149 P 1149
P
Sbjct: 563 P 563
Score = 44.0 bits (99), Expect = 0.032
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P L+ T L+VTV DV D + P F YE+ I EN + ++ LN ++ E
Sbjct: 218 GKPELTGTVQLLVTVLDVND-----NAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEG 272
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N + Y + +T + F ID G + + + D E ++ Y++++ A
Sbjct: 273 ANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDA 322
Score = 43.2 bits (97), Expect = 0.056
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKV------GTVIGKVKAVDPDLGQN 492
L S V ++V +LD NDN P + + ++ V G V+ KV+AVD D G N
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASD 540
+ Y+LQ ++ + PF++ TG +S RH L V D
Sbjct: 605 AWLSYELQPAAS-SPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKD 653
Score = 40.3 bits (90), Expect = 0.40
Identities = 40/131 (30%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 221 IDQDLGVG-ATL---RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQ 275
I QDLG+ A L + + S R L + NG LF+ +D + A + L+
Sbjct: 48 IAQDLGLELAELVPRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLE 107
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN-LPNGFSVLQVMATDKD 334
V ++ PL+ V++E+ D+NDN P F V + + E+ +P+ L+ A+D D
Sbjct: 108 VI---VDRPLQVFH--VDVEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLE-GASDAD 161
Query: 335 QGENGEFTYQL 345
G N TY+L
Sbjct: 162 VGANSVLTYRL 172
Score = 35.9 bits (79), Expect = 8.6
Identities = 51/191 (26%), Positives = 77/191 (40%), Gaps = 20/191 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGN--DRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTF 272
+ A D D A + Y L+ +R L S SV+ G ++ + LD + LQ
Sbjct: 477 VSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQ---- 532
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLP---EFEVDFYNISIVENLPN----GFSV 325
QV A P + +++ +LD NDN P E V + + +P G V
Sbjct: 533 -FQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 326 LQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLT--VRNQTVLDREAHSSLRMKVYA 383
+V A D D G N +Y+L + I R G T + VLD R+ V
Sbjct: 592 AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLV 651
Query: 384 KE-TNPSVVGT 393
K+ P++ T
Sbjct: 652 KDHGEPALTAT 662
>UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand
repeat protein; n=2; cellular organisms|Rep:
Autotransporter-associated beta strand repeat protein -
Marinomonas sp. MWYL1
Length = 3391
Score = 101 bits (242), Expect = 2e-19
Identities = 128/471 (27%), Positives = 188/471 (39%), Gaps = 51/471 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V V++ D NDN PV S S+ NA TVI A D D N + Y L
Sbjct: 2468 VTVSVNDLNDNTPVMTSSATG--SVNENADTSTVIYTATATDADGTATNNTLRYSLSGDD 2525
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANP--SERRYSLAVVTIEV 559
+ IN TG V++ S E + ++ V A+D A S + VT+ V
Sbjct: 2526 AALLD----INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSV 2581
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEE 616
N P I GA + N T V DA N +S+ L +
Sbjct: 2582 N-DLNDNAPVITS--GATAS--IDENAATSTVVYTATATDADGTSANNTISFSLTG--TD 2634
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGV 675
F V+ +GV+T+ + Y F +A A NL+ V V D+ND V
Sbjct: 2635 AAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPV 2694
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAIAE 734
+ GA + I EN+A + + ++ + G N + F + DI +
Sbjct: 2695 ITSGATASI----DENAATSTV--VYTATATDADGTSANNAISFSLTGTDAAAFDID-SS 2747
Query: 735 DGTIFTQKPLDREKRDVYRMTVIA------EFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
G + + D E + Y V+A FN G +S V + + D NDN PV
Sbjct: 2748 TGVVTLKASADYETKASYSFNVVATDNGAGNFNSGSLSTT--QAVIVSVNDLNDNTPVMT 2805
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVK 847
G + EN+ T I ATDAD N+ +Y+L G+ + +D TG V
Sbjct: 2806 SGA-TGSVNENADTSTVIYTAT---ATDADGTAANSTLVYSLSGDDADKLIIDATTGEVT 2861
Query: 848 FIGDSLDREKKIMYKLSLVARD-------TGGLSSEAELIIMIGDENDNKP 891
+ S D E + Y ++VA D +G LS+ +I+ + D NDN P
Sbjct: 2862 -LKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTP 2911
Score = 97.9 bits (233), Expect = 2e-18
Identities = 133/504 (26%), Positives = 201/504 (39%), Gaps = 43/504 (8%)
Query: 408 LETNAPLE-KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYE 466
L+ +A E +T+Y F + V T + L + V V++ D NDN PV
Sbjct: 2213 LKASADYETQTSYSF-NVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATG- 2270
Query: 467 FSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
S+ NA TVI A D D N + Y L + IN TG V++ S
Sbjct: 2271 -SVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDAALLD----INAVTGVVTLKAS 2325
Query: 526 PILEGR--HALFVEASDQPA-NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
E + ++ V A+D A N + S I N P + +
Sbjct: 2326 ADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNTPVMTSGATGSVDENA 2385
Query: 583 GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
++ I T+ G A N + Y L ++ ++ +G +T+ +
Sbjct: 2386 DTSTVIYTATGTDADGTA-ANNTLRYSL--SGDDADKLIIDATTGEVTLKASADYETKSS 2442
Query: 643 YDFEAVALQENA------NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
Y F +A A +LS TV V D+ND V+ A V EN+ +
Sbjct: 2443 YSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSSATGS----VNENADTST 2498
Query: 697 IGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMT 755
+ I+ + G T N +R+ ++ DI A G + + D E + Y
Sbjct: 2499 V--IYTATATDADGTATNNTLRYSLSGDDAALLDIN-AVTGVVTLKASADYETKSSYSFN 2555
Query: 756 VIAEFN-KGVISGAGI---YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
VIA N G ++ + VT+ + D NDN PV I EN+ T +
Sbjct: 2556 VIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGATAS-IDENAATSTVVYTAT- 2613
Query: 812 IKATDADEGTNA--LFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
ATDAD GT+A ++L G FDVD +TGVV + S D E K Y +++A D
Sbjct: 2614 --ATDAD-GTSANNTISFSLTGTDAAAFDVDSSTGVVT-LKASADYETKSSYSFNVIATD 2669
Query: 870 --TGGLSSEAELIIMIGDENDNKP 891
G L+ +I+ + D NDN P
Sbjct: 2670 NGAGNLTDTQAVIVSVNDLNDNAP 2693
Score = 91.1 bits (216), Expect = 2e-16
Identities = 121/469 (25%), Positives = 184/469 (39%), Gaps = 47/469 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V V++ D NDN PV S+ NA TVI D D N + Y L
Sbjct: 2359 VIVSVNDLNDNTPVMTSGATG--SVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDD 2416
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
I+ TG V++ S E + ++ V A+D N + S ++ T +
Sbjct: 2417 ----ADKLIIDATTGEVTLKASADYETKSSYSFNVIATD---NGAGNLNSGSLSTTQAVT 2469
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEEGV 618
+ + D M + V N T + DA N + Y L ++
Sbjct: 2470 VSVNDLNDNTPVMTSSATGSVNENADTSTVIYTATATDADGTATNNTLRYSL--SGDDAA 2527
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA------NLSIVTNATVHVVDVNDE 672
+ +GV+T+ + Y F +A A +LS TV V D+ND
Sbjct: 2528 LLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDN 2587
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIA 731
V+ GA + I EN+A + + ++ + G N + F + D+
Sbjct: 2588 APVITSGATASI----DENAATSTV--VYTATATDADGTSANNTISFSLTGTDAAAFDVD 2641
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ G + + D E + Y VIA N G + V + + D NDN PV
Sbjct: 2642 -SSTGVVTLKASADYETKSSYSFNVIATDN-GAGNLTDTQAVIVSVNDLNDNAPVITSGA 2699
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNA--LFMYTLFGEGKEMFDVDENTGVVKFI 849
I EN+ T + ATDAD GT+A ++L G FD+D +TGVV +
Sbjct: 2700 TAS-IDENAATSTVVYTAT---ATDAD-GTSANNAISFSLTGTDAAAFDIDSSTGVVT-L 2753
Query: 850 GDSLDREKKIMYKLSLVARD-------TGGLSSEAELIIMIGDENDNKP 891
S D E K Y ++VA D +G LS+ +I+ + D NDN P
Sbjct: 2754 KASADYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTP 2802
Score = 90.6 bits (215), Expect = 3e-16
Identities = 183/738 (24%), Positives = 268/738 (36%), Gaps = 104/738 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V V++ D NDN P S+ NA TVI A D D N + Y L
Sbjct: 1705 VTVSVNDLNDNTPAMTSGATG--SVNENADTSTVIYTATATDADGTATNNTLRYSLSGAD 1762
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ IN TG V++ S E + ++ V A+D N + S ++ T +
Sbjct: 1763 AALLD----INAVTGVVTLKASADYETKSSYSFNVIATD---NGAGNLNSGSLSTTQAVT 1815
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEEGV 618
+ + D M + V N T + DA N + Y L G + +
Sbjct: 1816 VSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSL-SGADAAL 1874
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA------NLSIVTNATVHVVDVNDE 672
+ +GV+T+ + Y F +A A +LS TV V D+ND
Sbjct: 1875 -LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDN 1933
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
V+ GA V EN+ + + I+ + G T N + D I
Sbjct: 1934 TPVMTSGATGS----VDENADTSTV--IYTATGTDADGTATNNTLRYSLSGDDADKLIID 1987
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIA------EFNKGVISGAGIYQVTIYIEDENDNPPV 786
A G + + D E + Y V+A FN G +S V + + D NDN PV
Sbjct: 1988 ATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTT--QAVIVSVNDLNDNTPV 2045
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
G + EN+ T I ATDAD GT A +T V
Sbjct: 2046 MTSGA-TGSVDENADTSTVIYTAT---ATDAD-GTAA-----------------NSTLVY 2083
Query: 847 KFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHR 906
GD D+ L+ T G E L E FN + ++
Sbjct: 2084 SLSGDDADK---------LIIDATTG---EVTLKASADYETQTSYSFNVVATDNGAGNFN 2131
Query: 907 ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD-SGLNGQ 965
L+ T I+ V N V G + EN T I A D D + N
Sbjct: 2132 SGSLSTTQA-VIVSVNDLNDNT-PVMTSGATGSVNENADTSTVIYTATATDADGTAANST 2189
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG 1023
+ Y + + AD L +I+ G V + S E++ + N+ A D G
Sbjct: 2190 LVYSLSGD--------DADKL------IIDATTGEVTLKASADYETQTSYSFNVVATDNG 2235
Query: 1024 -------NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FG 1075
+L+ +V V V D+ND+ PV + +V E T V+ ATDAD
Sbjct: 2236 AGNFNSGSLSTTQAVIVSVNDLNDNTPVMT-SGATGSVNENADTSTVIYTATATDADGTA 2294
Query: 1076 QNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX----XXXX 1131
N L Y + D L +I+ +TGV+++ D ET+ Y V+A DNG
Sbjct: 2295 TNNTLRYSLSGDDAAL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSL 2353
Query: 1132 XXXXXXXXXXXDVNDNSP 1149
D+NDN+P
Sbjct: 2354 STTQAVIVSVNDLNDNTP 2371
Score = 89.4 bits (212), Expect = 7e-16
Identities = 127/474 (26%), Positives = 187/474 (39%), Gaps = 52/474 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V V++ D ND+ PV S+ NA TVI A D D N + Y L
Sbjct: 1596 VTVSVNDLNDHTPVMTSGATG--SVNENADTSTVIYTATATDADGTATNNTLRYSLSGAD 1653
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANP--SERRYSLAVVTIEV 559
+ IN TG V++ S E + ++ V A+D A S + VT+ V
Sbjct: 1654 AALLD----INVVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSV 1709
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FEQNDVSYDLLHGYEE 616
N P + GA V N T + DA N + Y L G +
Sbjct: 1710 N-DLNDNTPAMTS--GATGS--VNENADTSTVIYTATATDADGTATNNTLRYSL-SGADA 1763
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA------NLSIVTNATVHVVDVN 670
+ + +GV+T+ + Y F +A A +LS TV V D+N
Sbjct: 1764 AL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLN 1822
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDD 729
D V+ GA V EN+ + + I+ + G T N +R+ ++ D
Sbjct: 1823 DNTPVMTSGATGS----VNENADTSTV--IYTATATDADGTATNNTLRYSLSGADAALLD 1876
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN-KGVISGAGI---YQVTIYIEDENDNPP 785
I A G + + D E + Y VIA N G ++ + VT+ + D NDN P
Sbjct: 1877 IN-AVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTP 1935
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTG 844
V G + EN+ T I TDAD TN Y+L G+ + +D TG
Sbjct: 1936 VMTSGA-TGSVDENADTSTVI---YTATGTDADGTATNNTLRYSLSGDDADKLIIDATTG 1991
Query: 845 VVKFIGDSLDREKKIMYKLSLVARD-------TGGLSSEAELIIMIGDENDNKP 891
V + S D E + Y ++VA D +G LS+ +I+ + D NDN P
Sbjct: 1992 EVT-LKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTP 2044
Score = 88.6 bits (210), Expect = 1e-15
Identities = 234/983 (23%), Positives = 344/983 (34%), Gaps = 142/983 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTS 503
V V++ D NDN PV S+ NA TVI A D D N + Y L
Sbjct: 1814 VTVSVNDLNDNTPVMTSGATG--SVNENADTSTVIYTATATDADGTATNNTLRYSLSGAD 1871
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANP--SERRYSLAVVTIEV 559
+ IN TG V++ S E + ++ V A+D A S + VT+ V
Sbjct: 1872 AALLD----INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSV 1927
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P + + ++ I T+ G A N + Y L ++
Sbjct: 1928 N-DLNDNTPVMTSGATGSVDENADTSTVIYTATGTDADGTA-TNNTLRYSL--SGDDADK 1983
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA------NLSIVTNATVHVVDVNDER 673
++ +G +T+ + Y F VA A +LS V V D+ND
Sbjct: 1984 LIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNT 2043
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
V+ GA V EN+ + + I+ + G + + D I A
Sbjct: 2044 PVMTSGATGS----VDENADTSTV--IYTATATDADGTAANSTLVYSLSGDDADKLIIDA 2097
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIA------EFNKGVISGAGIYQVTIYIEDENDNPPVF 787
G + + D E + Y V+A FN G +S V + + D NDN PV
Sbjct: 2098 TTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTT--QAVIVSVNDLNDNTPVM 2155
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVK 847
G + EN+ T I ATDAD GT A +T V
Sbjct: 2156 TSGA-TGSVNENADTSTVIYTAT---ATDAD-GTAA-----------------NSTLVYS 2193
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
GD D+ L+ T G E L E FN + ++
Sbjct: 2194 LSGDDADK---------LIIDATTG---EVTLKASADYETQTSYSFNVVATDNGAGNFNS 2241
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD-SGLNGQI 966
L+ T I+ V N V G + EN T I A D D + N +
Sbjct: 2242 GSLSTTQA-VIVSVNDLNDNT-PVMTSGATGSVNENADTSTVIYTATATDADGTATNNTL 2299
Query: 967 RYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG- 1023
RY + + A L+ IN G V + S E S + N+ A D G
Sbjct: 2300 RYSLSGD--------DAALLD------INAVTGVVTLKASADYETKSSYSFNVIATDNGA 2345
Query: 1024 -NLNDNI-----SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD-FGQ 1076
NLN +V V V D+ND+ PV + +V+E T V+ TDAD
Sbjct: 2346 GNLNSGSLSTTQAVIVSVNDLNDNTPVMT-SGATGSVDENADTSTVIYTATGTDADGTAA 2404
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGX----XXXXX 1132
N L Y + D D I TG +++ D ET+ Y V+A DNG
Sbjct: 2405 NNTLRYSLSGDDAD-KLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLS 2463
Query: 1133 XXXXXXXXXXDVNDNSPKFY-----AFDE-------LLEWKHPEADELSNHNFESVMMIP 1180
D+NDN+P + +E + +AD + +N +
Sbjct: 2464 TTQAVTVSVNDLNDNTPVMTSSATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSG 2523
Query: 1181 VYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMV 1240
A ++ NA G K A+ + + NL SLS+T + V
Sbjct: 2524 DDAALLDINAVTGVVTLKASAD----YETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTV 2579
Query: 1241 TVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDT 1300
+V D+ D + PV I+ I+EN + + T+ + T
Sbjct: 2580 SVNDLND-----NAPV-ITSGATASIDENAATSTVVYTATATDADGTSANNTISFSLTGT 2633
Query: 1301 DIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMT 1360
D F +D G + L S D E K +Y V +A D G
Sbjct: 2634 D-AAAFDVDSSTGVVTLKASADYETKSSYSFNV-----------------IATDNGAGNL 2675
Query: 1361 KYDVKVVVRIKDVNDNSPKFTNG 1383
V+V + D+NDN+P T+G
Sbjct: 2676 TDTQAVIVSVNDLNDNAPVITSG 2698
Score = 83.8 bits (198), Expect = 3e-14
Identities = 130/510 (25%), Positives = 195/510 (38%), Gaps = 50/510 (9%)
Query: 408 LETNAPLE-KTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYE 466
L+ +A E +T+Y F + V T + L + V V++ D NDN PV
Sbjct: 1995 LKASADYETQTSYSF-NVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSG--AT 2051
Query: 467 FSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
S+ NA TVI A D D N ++Y L I+ TG V++ S
Sbjct: 2052 GSVDENADTSTVIYTATATDADGTAANSTLVYSLSGDD----ADKLIIDATTGEVTLKAS 2107
Query: 526 PILEGR--HALFVEASDQPA-NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWV 582
E + ++ V A+D A N + S I N P + GA V
Sbjct: 2108 ADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTS--GATGS--V 2163
Query: 583 GSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNR 640
N T + DA N L G ++ ++ +G +T+ +
Sbjct: 2164 NENADTSTVIYTATATDADGTAANSTLVYSLSG-DDADKLIIDATTGEVTLKASADYETQ 2222
Query: 641 PMYDFEAVALQENA------NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAG 694
Y F VA A +LS V V D+ND V+ GA V EN+
Sbjct: 2223 TSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATG----SVNENADT 2278
Query: 695 AAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYR 753
+ + I+ + G T N +R+ ++ DI A G + + D E + Y
Sbjct: 2279 STV--IYTATATDADGTATNNTLRYSLSGDDAALLDIN-AVTGVVTLKASADYETKSSYS 2335
Query: 754 MTVIAEFN-KGVISGAGI---YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
VIA N G ++ + V + + D NDN PV G + EN+ T I
Sbjct: 2336 FNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTSTVI--- 2391
Query: 810 NIIKATDAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
TDAD N Y+L G+ + +D TG V + S D E K Y +++A
Sbjct: 2392 YTATGTDADGTAANNTLRYSLSGDDADKLIIDATTGEVT-LKASADYETKSSYSFNVIAT 2450
Query: 869 D-------TGGLSSEAELIIMIGDENDNKP 891
D +G LS+ + + + D NDN P
Sbjct: 2451 DNGAGNLNSGSLSTTQAVTVSVNDLNDNTP 2480
Score = 79.8 bits (188), Expect = 5e-13
Identities = 84/324 (25%), Positives = 136/324 (41%), Gaps = 29/324 (8%)
Query: 582 VGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP 641
V N T + DA + + ++Y L G + + + +G +T+ + +
Sbjct: 1518 VDENASTSTVIYTATATDA-DNDSLTYSL-SGTDAAL-LNINASTGAVTLKNSADYETKN 1574
Query: 642 MYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQI 700
Y F V ++ +L+ TV V D+ND V+ GA V EN+ + + I
Sbjct: 1575 TYSFNIVVTDSSSGHLTGSKAVTVSVNDLNDHTPVMTSGATGS----VNENADTSTV--I 1628
Query: 701 FHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ + G T N +R+ ++ DI + G + + D E + Y VIA
Sbjct: 1629 YTATATDADGTATNNTLRYSLSGADAALLDINVVT-GVVTLKASADYETKSSYSFNVIAT 1687
Query: 760 FN-KGVISGAGI---YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
N G ++ + VT+ + D NDN P G + EN+ T I AT
Sbjct: 1688 DNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAMTSGA-TGSVNENADTSTVIYTAT---AT 1743
Query: 816 DAD-EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----- 869
DAD TN Y+L G + D++ TGVV + S D E K Y +++A D
Sbjct: 1744 DADGTATNNTLRYSLSGADAALLDINAVTGVVT-LKASADYETKSSYSFNVIATDNGAGN 1802
Query: 870 --TGGLSSEAELIIMIGDENDNKP 891
+G LS+ + + + D NDN P
Sbjct: 1803 LNSGSLSTTQAVTVSVNDLNDNTP 1826
Score = 68.9 bits (161), Expect = 1e-09
Identities = 93/379 (24%), Positives = 149/379 (39%), Gaps = 43/379 (11%)
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
L+ G+L+ +V V V D+ND+ PV + +++E T V+ ATDAD G +AN
Sbjct: 2566 LNSGSLSTTQAVTVSVNDLNDNAPVIT-SGATASIDENAATSTVVYTATATDAD-GTSAN 2623
Query: 1080 LTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
T + TD F++ TGV+++ D ET+ Y V+A DNG
Sbjct: 2624 NTISFSLTGTDAAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNG-AGNLTDTQAVI 2682
Query: 1139 XXXXDVNDNSPKF-----YAFDE-------LLEWKHPEADELSNHNFESVMMIPVYKATI 1186
D+NDN+P + DE + +AD S +N S + A
Sbjct: 2683 VSVNDLNDNAPVITSGATASIDENAATSTVVYTATATDADGTSANNAISFSLTGTDAAAF 2742
Query: 1187 EENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVP 1246
+ ++ G K A+ ++ N SLS+T ++V+V D+
Sbjct: 2743 DIDSSTGVVTLKASADYETKASYSFNVVATD----NGAGNFNSGSLSTTQAVIVSVNDLN 2798
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYYILNENDTDIRR 1304
D + PV S + EN + + + T+ Y L+ +D D
Sbjct: 2799 D-----NTPVMTSGATG-SVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDAD--- 2849
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
+ID G + L S D E + +Y V A A + G
Sbjct: 2850 KLIIDATTGEVTLKASADYETQTSYSFNVVATDNG------------AGNFNSGSLSTTQ 2897
Query: 1365 KVVVRIKDVNDNSPKFTNG 1383
V+V + D+NDN+P + G
Sbjct: 2898 AVIVSVNDLNDNTPTVSAG 2916
Score = 68.5 bits (160), Expect = 1e-09
Identities = 118/471 (25%), Positives = 176/471 (37%), Gaps = 71/471 (15%)
Query: 940 IPENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+ EN T I D D + N +RY + + AD L +I+
Sbjct: 2381 VDENADTSTVIYTATGTDADGTAANNTLRYSLSGD--------DADKL------IIDATT 2426
Query: 999 GHVIVARSLPPE--SEFRLNISALDGG--NLNDNI-----SVRVFVKDVNDHFPVFKKTW 1049
G V + S E S + N+ A D G NLN +V V V D+ND+ PV +
Sbjct: 2427 GEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSSA 2486
Query: 1050 YNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+V E T V+ ATDAD N L Y + D L +I+ +TGV+++
Sbjct: 2487 TG-SVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDAAL-LDINAVTGVVTLKASA 2544
Query: 1109 DRETEDKYILTVVARDNGX----XXXXXXXXXXXXXXXDVNDNSPKF-----YAFDE--- 1156
D ET+ Y V+A DNG D+NDN+P + DE
Sbjct: 2545 DYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGATASIDENAA 2604
Query: 1157 ----LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
+ +AD S +N S + A + ++ G K A D+ +
Sbjct: 2605 TSTVVYTATATDADGTSANNTISFSLTGTDAAAFDVDSSTGVVTLKASA---DYETKSS- 2660
Query: 1213 LILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
YS G +L+ T ++V+V D+ D + PV I+ I+EN
Sbjct: 2661 ---YSFNVIATDNGAG--NLTDTQAVIVSVNDLND-----NAPV-ITSGATASIDENAAT 2709
Query: 1273 PVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVI 1332
+ + T+ + TD F ID G + L S D E K +Y
Sbjct: 2710 STVVYTATATDADGTSANNAISFSLTGTD-AAAFDIDSSTGVVTLKASADYETKASYSFN 2768
Query: 1333 VRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
V A A + G V+V + D+NDN+P T+G
Sbjct: 2769 VVATDNG------------AGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSG 2807
Score = 66.5 bits (155), Expect = 5e-09
Identities = 104/414 (25%), Positives = 161/414 (38%), Gaps = 52/414 (12%)
Query: 994 INERHGHVIVARSLPPESE--FRLNISALDG--GNLNDNISVRVFVKDVNDHFPVFKKTW 1049
IN G V + S E++ + NI D G+L + +V V V D+NDH PV +
Sbjct: 1555 INASTGAVTLKNSADYETKNTYSFNIVVTDSSSGHLTGSKAVTVSVNDLNDHTPVMT-SG 1613
Query: 1050 YNFNVEEAQYTRRVLGKVDATDAD-FGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
+V E T V+ ATDAD N L Y + +D L +I+ +TGV+++
Sbjct: 1614 ATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGADAAL-LDINVVTGVVTLKASA 1672
Query: 1109 DRETEDKYILTVVARDNGX----XXXXXXXXXXXXXXXDVNDNSPKFY-----AFDE--- 1156
D ET+ Y V+A DNG D+NDN+P + +E
Sbjct: 1673 DYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAMTSGATGSVNENAD 1732
Query: 1157 ----LLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
+ +AD + +N + A ++ NA G K A+ +
Sbjct: 1733 TSTVIYTATATDADGTATNNTLRYSLSGADAALLDINAVTGVVTLKASAD----YETKSS 1788
Query: 1213 LILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNA 1272
+ NL SLS+T + V+V D+ D + PV S + EN +
Sbjct: 1789 YSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLND-----NTPVMTSGATG-SVNENADT 1842
Query: 1273 PVELVSLNLTE---HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
+ + T+ N +R Y L+ D + I+ G + L S D E K +Y
Sbjct: 1843 STVIYTATATDADGTATNNTLR-YSLSGADAAL---LDINAVTGVVTLKASADYETKSSY 1898
Query: 1330 EVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
V A A ++ G V V + D+NDN+P T+G
Sbjct: 1899 SFNVIATDNG------------AGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSG 1940
Score = 60.9 bits (141), Expect = 3e-07
Identities = 57/188 (30%), Positives = 80/188 (42%), Gaps = 12/188 (6%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG+D L +++V G + L+ D + + + N A LN+ L T
Sbjct: 2516 TLRYSL-SGDDAALLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 2574
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQL-D 346
QA V + + DLNDN P SI EN V ATD D N ++ L
Sbjct: 2575 QA-VTVSVNDLNDNAPVI-TSGATASIDENAATSTVVYTATATDADGTSANNTISFSLTG 2632
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQ 406
AF +D +G +T++ D E SS V A + G D+Q +
Sbjct: 2633 TDAAAFDVDSSTGVVTLKASA--DYETKSSYSFNVIATDNG---AGNLTDTQAVIV-SVN 2686
Query: 407 PLETNAPL 414
L NAP+
Sbjct: 2687 DLNDNAPV 2694
Score = 52.8 bits (121), Expect = 7e-05
Identities = 48/159 (30%), Positives = 67/159 (42%), Gaps = 8/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG+D L +++V G + L+ D + + + N A LN+ L T
Sbjct: 2298 TLRYSL-SGDDAALLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 2356
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD- 346
QA V + + DLNDN P S+ EN + TD D N Y L
Sbjct: 2357 QA-VIVSVNDLNDNTPVMTSGATG-SVDENADTSTVIYTATGTDADGTAANNTLRYSLSG 2414
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D ID +G +T++ D E SS V A +
Sbjct: 2415 DDADKLIIDATTGEVTLKASA--DYETKSSYSFNVIATD 2451
Score = 52.8 bits (121), Expect = 7e-05
Identities = 53/190 (27%), Positives = 78/190 (41%), Gaps = 11/190 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG+D +D+ G + L+ D + + + N A LN+ L T
Sbjct: 2407 TLRYSL-SGDDADKLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 2465
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD- 346
QA V + + DLNDN P S+ EN + ATD D N Y L
Sbjct: 2466 QA-VTVSVNDLNDNTPVMTSSATG-SVNENADTSTVIYTATATDADGTATNNTLRYSLSG 2523
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV--GTFADSQRIAKWR 404
D I+ +G +T++ D E SS V A + + G+ + +Q +
Sbjct: 2524 DDAALLDINAVTGVVTLKASA--DYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTV-S 2580
Query: 405 RQPLETNAPL 414
L NAP+
Sbjct: 2581 VNDLNDNAPV 2590
Score = 51.6 bits (118), Expect = 2e-04
Identities = 48/159 (30%), Positives = 67/159 (42%), Gaps = 8/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG D L +++V G + L+ D + + + N A LN+ L T
Sbjct: 1753 TLRYSL-SGADAALLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 1811
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLDD 347
QA V + + DLNDN P S+ EN + ATD D N Y L
Sbjct: 1812 QA-VTVSVNDLNDNTPVMTSGATG-SVNENADTSTVIYTATATDADGTATNNTLRYSLSG 1869
Query: 348 PKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A I+ +G +T++ D E SS V A +
Sbjct: 1870 ADAALLDINAVTGVVTLKASA--DYETKSSYSFNVIATD 1906
Score = 51.6 bits (118), Expect = 2e-04
Identities = 47/159 (29%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG D L +++V G + L+ D + + + N A LN+ L T
Sbjct: 1862 TLRYSL-SGADAALLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 1920
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD- 346
QA V + + DLNDN P S+ EN + TD D N Y L
Sbjct: 1921 QA-VTVSVNDLNDNTPVMTSGATG-SVDENADTSTVIYTATGTDADGTATNNTLRYSLSG 1978
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D ID +G +T++ D E +S V A +
Sbjct: 1979 DDADKLIIDATTGEVTLKASA--DYETQTSYSFNVVATD 2015
Score = 50.8 bits (116), Expect = 3e-04
Identities = 48/159 (30%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG D L ++ V G + L+ D + + + N A LN+ L T
Sbjct: 1644 TLRYSL-SGADAALLDINVVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTT 1702
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLDD 347
QA V + + DLNDN P S+ EN + ATD D N Y L
Sbjct: 1703 QA-VTVSVNDLNDNTPAMTSGATG-SVNENADTSTVIYTATATDADGTATNNTLRYSLSG 1760
Query: 348 PKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A I+ +G +T++ D E SS V A +
Sbjct: 1761 ADAALLDINAVTGVVTLKASA--DYETKSSYSFNVIATD 1797
Score = 50.4 bits (115), Expect = 4e-04
Identities = 82/330 (24%), Positives = 124/330 (37%), Gaps = 24/330 (7%)
Query: 71 GAG-LNQ--ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS 127
GAG LN +S +VTV + D+NDN P+ + + ++DE T + A
Sbjct: 2562 GAGNLNSGSLSTTQAVTVSVNDLNDNAPV-ITSGATASIDENAATSTVVYT-ATATDADG 2619
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
+ T+ LT D AFD D T + Y S A ++ +
Sbjct: 2620 TSANNTISFSLT-GTDAAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDT 2678
Query: 185 RKVLDYDAGDKEFQLVIMASGKR--IHKEILFPEPIH---AIDQDLGVGATLRYEL-ISG 238
+ V+ D ++ SG I + ++ A D D G A ++G
Sbjct: 2679 QAVI-VSVNDLNDNAPVITSGATASIDENAATSTVVYTATATDAD-GTSANNAISFSLTG 2736
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTAQARVEIELL 297
D F +DS G + L+ D + + + N A N+ L T QA V + +
Sbjct: 2737 TDAAAFDIDSSTGVVTLKASADYETKASYSFNVVATDNGAGNFNSGSLSTTQA-VIVSVN 2795
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD-DPKGAFSID 355
DLNDN P S+ EN + ATD D N Y L D ID
Sbjct: 2796 DLNDNTPVMTSGATG-SVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDADKLIID 2854
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G +T++ D E +S V A +
Sbjct: 2855 ATTGEVTLKASA--DYETQTSYSFNVVATD 2882
Score = 50.0 bits (114), Expect = 5e-04
Identities = 46/159 (28%), Positives = 65/159 (40%), Gaps = 8/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
TLRY L SG+D +D+ G + L+ D + + + N A N+ L T
Sbjct: 1971 TLRYSL-SGDDADKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTT 2029
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD- 346
QA V + + DLNDN P S+ EN + ATD D N Y L
Sbjct: 2030 QA-VIVSVNDLNDNTPVMTSGATG-SVDENADTSTVIYTATATDADGTAANSTLVYSLSG 2087
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D ID +G +T++ D E +S V A +
Sbjct: 2088 DDADKLIIDATTGEVTLKASA--DYETQTSYSFNVVATD 2124
Score = 48.0 bits (109), Expect = 0.002
Identities = 48/170 (28%), Positives = 68/170 (40%), Gaps = 9/170 (5%)
Query: 220 AIDQD-LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D +TL Y L SG+D +D+ G + L+ D + + + N A
Sbjct: 2069 ATDADGTAANSTLVYSL-SGDDADKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGA 2127
Query: 279 SQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
N+ L T QA V + + DLNDN P S+ EN + ATD D
Sbjct: 2128 GNFNSGSLSTTQA-VIVSVNDLNDNTPVMTSGATG-SVNENADTSTVIYTATATDADGTA 2185
Query: 337 ENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y L D ID +G +T++ D E +S V A +
Sbjct: 2186 ANSTLVYSLSGDDADKLIIDATTGEVTLKASA--DYETQTSYSFNVVATD 2233
Score = 46.8 bits (106), Expect = 0.005
Identities = 48/170 (28%), Positives = 68/170 (40%), Gaps = 9/170 (5%)
Query: 220 AIDQD-LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D +TL Y L SG+D +D+ G + L+ D + + + N A
Sbjct: 2178 ATDADGTAANSTLVYSL-SGDDADKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGA 2236
Query: 279 SQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
N+ L T QA V + + DLNDN P S+ EN + ATD D
Sbjct: 2237 GNFNSGSLSTTQA-VIVSVNDLNDNTPVMTSGATG-SVNENADTSTVIYTATATDADGTA 2294
Query: 337 ENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N Y L D I+ +G +T++ D E SS V A +
Sbjct: 2295 TNNTLRYSLSGDDAALLDINAVTGVVTLKASA--DYETKSSYSFNVIATD 2342
Score = 44.0 bits (99), Expect = 0.032
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
NV+E T V+ ATDAD N +LTY + +D L I+ TG +++ D ET
Sbjct: 1517 NVDENASTSTVIYTATATDAD---NDSLTYSLSGTDAAL-LNINASTGAVTLKNSADYET 1572
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
++ Y +V D+ D+ND++P
Sbjct: 1573 KNTYSFNIVVTDS-SSGHLTGSKAVTVSVNDLNDHTP 1608
Score = 40.3 bits (90), Expect = 0.40
Identities = 66/304 (21%), Positives = 113/304 (37%), Gaps = 23/304 (7%)
Query: 32 VSVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYI 87
+S L + + D DS VV + D++ +++ G ++ +V V +
Sbjct: 2626 ISFSLTGTDAAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSV 2685
Query: 88 EDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAF 147
D+NDN P+ + + ++DE T + A + + LT D AF
Sbjct: 2686 NDLNDNAPV-ITSGATASIDENAATSTVVYT-ATATDADGTSANNAISFSLT-GTDAAAF 2742
Query: 148 DRDKPN---TPNSDVHYSIVSGNDDGHFALESS----HKPVLLLRKVLDYDAGDKEFQLV 200
D D T + Y + A ++ + L + + D
Sbjct: 2743 DIDSSTGVVTLKASADYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTP 2802
Query: 201 IMASGKR--IHKEILFPEPIH---AIDQD-LGVGATLRYELISGNDRKLFSLDSVNGSLF 254
+M SG +++ I+ A D D +TL Y L SG+D +D+ G +
Sbjct: 2803 VMTSGATGSVNENADTSTVIYTATATDADGTAANSTLVYSL-SGDDADKLIIDATTGEVT 2861
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
L+ D + + + N A N+ L T QA V + + DLNDN P
Sbjct: 2862 LKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQA-VIVSVNDLNDNTPTVSAGAETA 2920
Query: 314 SIVE 317
+VE
Sbjct: 2921 ILVE 2924
Score = 39.5 bits (88), Expect = 0.69
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 11/158 (6%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+L Y L SG D L ++++ G++ L+ D + ++ N V + L T
Sbjct: 1540 SLTYSL-SGTDAALLNINASTGAVTLKNSADYETKNTYSFNIVVTDSSSGHL-----TGS 1593
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLDDP 348
V + + DLND+ P S+ EN + ATD D N Y L
Sbjct: 1594 KAVTVSVNDLNDHTPVMTSGATG-SVNENADTSTVIYTATATDADGTATNNTLRYSLSGA 1652
Query: 349 KGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A I+ +G +T++ D E SS V A +
Sbjct: 1653 DAALLDINVVTGVVTLKASA--DYETKSSYSFNVIATD 1688
>UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28;
Euteleostomi|Rep: Protocadherin-20 precursor - Homo
sapiens (Human)
Length = 924
Score = 100 bits (240), Expect = 3e-19
Identities = 115/465 (24%), Positives = 204/465 (43%), Gaps = 36/465 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L+ + + + D NDN P+F S + ++ NA VGT I V+AVD DLG N + Y
Sbjct: 273 LLGSATLTIGISDINDNCPLFTDSQI-NVTVYGNATVGTPIAAVQAVDKDLGTNAQITYS 331
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPANPSERRYSLAVV 555
+ F ++ NTG + + +LE H L + A+ P+ ++++
Sbjct: 332 YSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLES-HKLTILANGPGCIPAVITALVSII 390
Query: 556 TIEVTRGTKGNKPDI-PDFMGAPYE--FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLL- 611
+ + R P+I P ++ + ++ + T + + D + V+ L
Sbjct: 391 KV-IFR-----PPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDG 444
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVND 671
G P+ ++ + + Y+ VA + V ++D ND
Sbjct: 445 EGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNSEG-FHVKRVIKVQLLDDND 503
Query: 672 ERGVLLKGAHSPII-FHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
+ L+ P+I ++EN S A + +++ T+ S G V + + D
Sbjct: 504 NAPIFLQ----PLIELTIEENNSPNAFLTKLYATDADS---EERGQVSYFLG--PDAPSY 554
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++ + G + LDRE+++ YR TV A + G + V + + D+NDN P F
Sbjct: 555 FSLDSVTGILTVSTQLDREEKEKYRYTVRA-VDCGKPPRESVATVALTVLDKNDNSPRFI 613
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
+ + F+ EN EI +I TDAD G N ++ + ++F +D G+++
Sbjct: 614 NKDFSFFVPENFPGYGEI---GVISVTDADAGRNGWVALSVVNQ-SDIFVIDTGKGMLR- 668
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
SLDRE++ Y L + A D G LSS A++ I++ D NDN P
Sbjct: 669 AKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPP 713
Score = 81.4 bits (192), Expect = 2e-13
Identities = 83/324 (25%), Positives = 137/324 (42%), Gaps = 21/324 (6%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
++V + D ND+ P+F + +EE L K+ ATDAD + ++YF+ P D
Sbjct: 494 IKVQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGP-DAP 552
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F + +TG+L+V+ +LDRE ++KY TV A D G D NDNSP+
Sbjct: 553 SYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCG-KPPRESVATVALTVLDKNDNSPR 611
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
F D + PE + + + +I V A N + +V V +D I G
Sbjct: 612 FINKD--FSFFVPE----NFPGYGEIGVISVTDADAGRNGWVALSV--VNQSDIFVIDTG 663
Query: 1211 NGLILYSLPQRKNQQNL----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISR 1260
G++ + + QQ+ G P+LSSTA + + + D+ D + P
Sbjct: 664 KGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMS 723
Query: 1261 YYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRS 1320
Y + +PV V + N + Y I+ +F IDP+ G + L +
Sbjct: 724 YLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPR-PESFRIDPKTGNITLEEA 782
Query: 1321 PDREVKDTYEVIVRAERQKYSREL 1344
+ + ++V+ Y L
Sbjct: 783 LLQTDYGLHRLLVKVSDHGYPEPL 806
Score = 66.1 bits (154), Expect = 7e-09
Identities = 48/156 (30%), Positives = 74/156 (47%), Gaps = 9/156 (5%)
Query: 740 TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
T KP+D E + Y + V+A ++G I + + D+NDN P+F E I EN
Sbjct: 464 TTKPMDYELQQFYEVAVVAWNSEGFHVKRVI---KVQLLDDNDNAPIFLQPLIELTIEEN 520
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKI 859
+ + + ATDAD Y L + F +D TG++ + LDRE+K
Sbjct: 521 NSPNAFLTK---LYATDADSEERGQVSYFLGPDAPSYFSLDSVTGILT-VSTQLDREEKE 576
Query: 860 MYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
Y+ ++ A D G S A + + + D+NDN P F
Sbjct: 577 KYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRF 612
Score = 65.7 bits (153), Expect = 9e-09
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 14/207 (6%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE +D Y +IAE + G G +TI I D NDN P+F + + N+ +G
Sbjct: 251 LDRETQDQYVSIIIAE-DGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVG 309
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDENTGVVKFIGDSLDREKKI 859
T I ++A D D GTNA Y+ + K++F +DENTGV+K +
Sbjct: 310 TPIA---AVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLF-SKIGGSVLE 365
Query: 860 MYKLSLVARDTG----GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN-GTA 914
+KL+++A G +++ +I +I + P + E + V + +N A
Sbjct: 366 SHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIA 425
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIP 941
FTI + + K K +D GP L P
Sbjct: 426 FFTIRDPEGKYKVNCYLDGEGPFRLSP 452
Score = 64.1 bits (149), Expect = 3e-08
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 10/171 (5%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
F ++A D D + Y L G D FSLDSV G L + +LD + + +
Sbjct: 526 FLTKLYATDADSEERGQVSYFL--GPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYT-- 581
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
V+A P + + A V + +LD NDN P F ++ + EN P + + TD
Sbjct: 582 ---VRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTD 638
Query: 333 KDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
D G NG + + F ID G L R + LDRE SS + V A
Sbjct: 639 ADAGRNGWVALSVVNQSDIFVIDTGKGML--RAKVSLDREQQSSYTLWVEA 687
Score = 62.1 bits (144), Expect = 1e-07
Identities = 69/254 (27%), Positives = 114/254 (44%), Gaps = 22/254 (8%)
Query: 599 DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDF--EAVALQENANL 656
D+ E+ VSY L G + F+++ +G++TV L R + Y + AV +
Sbjct: 536 DSEERGQVSYFL--GPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRE 593
Query: 657 SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
S+ T A V+D ND + S F V EN G G+I +++ G V
Sbjct: 594 SVATVALT-VLDKNDNSPRFINKDFS---FFVPENFPG--YGEIGVISVTDADAGRNGWV 647
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+ NQ D+ + G + + LDRE++ Y + V A + G + + ++TI
Sbjct: 648 ALSVVNQSDIF--VIDTGKGMLRAKVSLDREQQSSYTLWVEA-VDGGEPALSSTAKITIL 704
Query: 777 IEDENDNPP--VFEHATYEGFIMENSKI-GTEIKMDNIIKATDADEGTNALFMYTLFGE- 832
+ D NDNPP +F + ++ S + G+ + + A D D G NA+ Y++ G
Sbjct: 705 LLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPV---TEVYAVDKDTGMNAVIAYSIIGRR 761
Query: 833 --GKEMFDVDENTG 844
E F +D TG
Sbjct: 762 GPRPESFRIDPKTG 775
Score = 61.3 bits (142), Expect = 2e-07
Identities = 47/153 (30%), Positives = 77/153 (50%), Gaps = 14/153 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I D D G + +++ +D +F +D+ G L ++ LD E Q +++ L V+
Sbjct: 634 ISVTDADAGRNGWVALSVVNQSD--IFVIDTGKG--MLRAKVSLDRE---QQSSYTLWVE 686
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN---GFSVLQVMATDKD 334
A P ++ A++ I LLD+NDN P N+S + LP+ G V +V A DKD
Sbjct: 687 AVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKD 746
Query: 335 QGENGEFTYQLDDPKG----AFSIDPRSGWLTV 363
G N Y + +G +F IDP++G +T+
Sbjct: 747 TGMNAVIAYSIIGRRGPRPESFRIDPKTGNITL 779
Score = 58.8 bits (136), Expect = 1e-06
Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 9/138 (6%)
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+V I I D NDN P F + ++ EN+ + T + +++ A D D G N + Y L
Sbjct: 167 KVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEH--PAVDPDVGINGVQTYRLLD 224
Query: 832 -EGKEMFDVDENTGVVK----FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIG 884
G DV+EN + + +LDRE + Y ++A D G L A L I I
Sbjct: 225 YHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGIS 284
Query: 885 DENDNKPEFNQIEENSKV 902
D NDN P F + N V
Sbjct: 285 DINDNCPLFTDSQINVTV 302
Score = 58.8 bits (136), Expect = 1e-06
Identities = 65/232 (28%), Positives = 96/232 (41%), Gaps = 28/232 (12%)
Query: 929 LDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + P+FL P EN + KL A D DS GQ+ Y ++ P
Sbjct: 499 LDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSY------FLGP--- 549
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKD 1037
+ YF ++ G + V+ L E ++R + A+D G +V + V D
Sbjct: 550 -----DAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLD 604
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
ND+ P F ++F V E +G + TDAD G+N + + + +D+ F I
Sbjct: 605 KNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSV-VNQSDI-FVIDT 662
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
G+L LDRE + Y L V A D G D+NDN P
Sbjct: 663 GKGMLRAKVSLDREQQSSYTLWVEAVDGG-EPALSSTAKITILLLDINDNPP 713
Score = 57.6 bits (133), Expect = 2e-06
Identities = 53/196 (27%), Positives = 90/196 (45%), Gaps = 18/196 (9%)
Query: 940 IPENIPIGTTI-IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+PEN P+ T + I+ A+D D G+NG Y + D E + ER
Sbjct: 191 VPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDY----HGMFTLDVEENEN----GERT 242
Query: 999 GHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
++IV +L E++ + I A DGG+ L + ++ + + D+ND+ P+F + N V
Sbjct: 243 PYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTV 302
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYF----IQPSDTDLPFEISPLTGVLSVNGELDR 1110
+ V A D D G NA +TY + + DL F + TGV+ + ++
Sbjct: 303 YGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDL-FHLDENTGVIKLFSKIGG 361
Query: 1111 ETEDKYILTVVARDNG 1126
+ + LT++A G
Sbjct: 362 SVLESHKLTILANGPG 377
Score = 55.6 bits (128), Expect = 1e-05
Identities = 64/237 (27%), Positives = 103/237 (43%), Gaps = 18/237 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V LLD NDN P+F+ L E +++ N + K+ A D D + G V Y L +
Sbjct: 494 IKVQLLDDNDNAPIFL-QPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDA- 551
Query: 505 LTITSPFKINPNTG--TVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
S F ++ TG TVS + ++ V A D P E +V T+ +T
Sbjct: 552 ---PSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRE-----SVATVALTVL 603
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
K + + P F+ + F+V N +G I V DA + + L + F +
Sbjct: 604 DKND--NSPRFINKDFSFFVPENFPGYGEIGVISVTDA-DAGRNGWVALSVVNQSDIFVI 660
Query: 623 EERSGVITVVDDLSRYNRPMYDF--EAVALQENANLSIVTNATVHVVDVNDERGVLL 677
+ G++ L R + Y EAV E A LS T+ ++D+ND ++L
Sbjct: 661 DTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPA-LSSTAKITILLLDINDNPPLVL 716
Score = 55.6 bits (128), Expect = 1e-05
Identities = 38/94 (40%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVE-NLPNGFSVLQVMATDKDQGENGEFTYQL-DDPK 349
++++LLD NDN P F ++I E N PN F + ++ ATD D E G+ +Y L D
Sbjct: 494 IKVQLLDDNDNAPIFLQPLIELTIEENNSPNAF-LTKLYATDADSEERGQVSYFLGPDAP 552
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
FS+D +G LTV Q LDRE R V A
Sbjct: 553 SYFSLDSVTGILTVSTQ--LDREEKEKYRYTVRA 584
Score = 53.6 bits (123), Expect = 4e-05
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+ V++ ++D+ND+ P F + + V E A R+ + A D D G N TY +
Sbjct: 166 VKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDY 225
Query: 1088 DTDLPFEI-----SPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
++ T L V G LDRET+D+Y+ ++A D G
Sbjct: 226 HGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGG-SPPLLGSATLTIGIS 284
Query: 1143 DVNDNSPKF 1151
D+NDN P F
Sbjct: 285 DINDNCPLF 293
Score = 53.2 bits (122), Expect = 5e-05
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query: 430 ENIEYYDEQLMSFVNVEVTLLDANDNNPV--FVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
E ++ + L S + + LLD NDN P+ F SN+ + + G+ + +V AVD
Sbjct: 686 EAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDK 745
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASD 540
D G N ++ Y + S F+I+P TG +++ E+ + G H L V+ SD
Sbjct: 746 DTGMNAVIAYSIIGRRGPRPES-FRIDPKTGNITLEEALLQTDYGLHRLLVKVSD 799
Score = 52.8 bits (121), Expect = 7e-05
Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 15/168 (8%)
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVMATDKDQGENGEFTYQLDDPK 349
+V+I + D+NDN P+F V ++ + EN P N ++ A D D G NG TY+L D
Sbjct: 167 KVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYH 226
Query: 350 GAFSID-------PRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIA 401
G F++D R+ +L V LDRE + A++ +P ++G+ + I+
Sbjct: 227 GMFTLDVEENENGERTPYLIVMG--ALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGIS 284
Query: 402 KWRRQ-PLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVT 448
PL T++ + T Y VGT ++ D+ L + N ++T
Sbjct: 285 DINDNCPLFTDSQINVTVY-GNATVGTPIAAVQAVDKDLGT--NAQIT 329
Score = 50.0 bits (114), Expect = 5e-04
Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 15/150 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD---SVNGSL--FLEKELDLDAEHNLQANTFVL 274
A+D D+G+ Y L+ + +F+LD + NG +L LD E Q +V
Sbjct: 207 AVDPDVGINGVQTYRLLDYHG--MFTLDVEENENGERTPYLIVMGALDRETQDQ---YVS 261
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A +P A + I + D+NDN P F N+++ N G + V A DKD
Sbjct: 262 IIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKD 321
Query: 335 QGENGEFTYQLDD-----PKGAFSIDPRSG 359
G N + TY K F +D +G
Sbjct: 322 LGTNAQITYSYSQKVPQASKDLFHLDENTG 351
Score = 44.0 bits (99), Expect = 0.032
Identities = 53/203 (26%), Positives = 87/203 (42%), Gaps = 19/203 (9%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG-KVKAVDPDLGQNGMV 495
++ FV V++ + D NDN P F P + + NA V T + + AVDPD+G NG+
Sbjct: 160 QEYFRFVKVKIAIRDINDNAPQF-PVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQ 218
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPAN--PSERRYSLA 553
Y L + T + N N +P L AL E DQ + +E S
Sbjct: 219 TYRLLDYHGM-FTLDVEENENG-----ERTPYLIVMGALDRETQDQYVSIIIAEDGGSPP 272
Query: 554 VV-TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLH 612
++ + +T G + P F + V N +GT + ++ D + + + +
Sbjct: 273 LLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVD--KDLGTNAQITY 330
Query: 613 GYEEGVP------FAVEERSGVI 629
Y + VP F ++E +GVI
Sbjct: 331 SYSQKVPQASKDLFHLDENTGVI 353
Score = 37.1 bits (82), Expect = 3.7
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 1425 LVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPR---FAIDPVSGTVRVVAAL 1479
LV L + +T A D D G+NA I Y I+ + PR F IDP +G + + AL
Sbjct: 726 LVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEAL 783
>UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor (Vascular
cadherin-2) (Vascular endothelial cadherin-2)
(VE-cadherin-2) (VE-cad-2).; n=1; Takifugu rubripes|Rep:
Protocadherin-12 precursor (Vascular cadherin-2)
(Vascular endothelial cadherin-2) (VE-cadherin-2)
(VE-cad-2). - Takifugu rubripes
Length = 1134
Score = 100 bits (239), Expect = 4e-19
Identities = 118/436 (27%), Positives = 188/436 (43%), Gaps = 64/436 (14%)
Query: 729 DIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
D+ + +GT + + LDRE +D ++++A ++KG +G + + I+D NDN
Sbjct: 154 DVTVGPEGTKQAELVIIRELDREVQDSVDLSLVA-WDKGDPPRSGSTLIHVRIQDSNDNS 212
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVD 840
P FE + + EN+ GT I +KATD D+G N +Y+L E + + VD
Sbjct: 213 PTFEDSAPTVELPENTARGTTIIS---LKATDPDQGVNGEVVYSLSKHTQPEVQRLIAVD 269
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEE 898
T V + LD E + Y++ + ARD G + + +L I + D NDN P
Sbjct: 270 PQTAAVS-LKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAP------- 321
Query: 899 NSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDL 958
RI + + G T++E PK+ F L L+ LD
Sbjct: 322 ----RILADWDRSSFPGPTVLEGAPKDTF---------LSLV-------------TVLDA 355
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNIS 1018
DSG NG+++ +++ S ++ Y ++ +G + + + L +
Sbjct: 356 DSGQNGKVK----AQILEGSGPFSLKHMQGGNYKIVT--NGTL----DREQVTWYNLTLL 405
Query: 1019 ALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
A D G+ L+ + V V D ND+ PVF Y + EE T + KV+A D D
Sbjct: 406 AQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDL 465
Query: 1077 NANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXX 1133
+ ++YFI+ +D D F I +GV+ LD E + V A D G
Sbjct: 466 SGRVSYFIRNVTGADVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVEAIDQG-HPPLSS 524
Query: 1134 XXXXXXXXXDVNDNSP 1149
DVNDN P
Sbjct: 525 SATVQIQVQDVNDNYP 540
Score = 76.6 bits (180), Expect = 5e-12
Identities = 125/558 (22%), Positives = 222/558 (39%), Gaps = 45/558 (8%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++ Y M+ + V V ++D ND++P F P+ + + A + I +AVDPD G
Sbjct: 78 SVLYRKSGAMNCLRVRVEVMDQNDHSPQF-PNAEQDVEISEIAGLRMRIPLERAVDPDAG 136
Query: 491 QNGMVLYDLQ--RTSNLTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSE 547
NG+ Y L R L +T + V + E ++ L + A D+ +P
Sbjct: 137 PNGLQTYSLSVNRYFALDVTVGPEGTKQAELVIIRELDREVQDSVDLSLVAWDK-GDPPR 195
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
+L V I+ + N P D AP + N GT++ ++ D + +
Sbjct: 196 SGSTLIHVRIQ---DSNDNSPTFED--SAP-TVELPENTARGTTIISLKATDPDQGVNGE 249
Query: 606 VSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
V Y L + V AV+ ++ +++ L + Y+ A N +I
Sbjct: 250 VVYSLSKHTQPEVQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGPN-AIPAYCK 308
Query: 664 VHV--VDVNDERGVLL-----KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+H+ +DVND +L P + ++ + + NG
Sbjct: 309 LHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQ---NGKVKA 365
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+ L + + + I T LDRE+ Y +T++A+ + G + + +++
Sbjct: 366 QILEGSGPFSLKHMQ-GGNYKIVTNGTLDREQVTWYNLTLLAQ-DYGDPPLSSVKHMSVQ 423
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD---EGTNALFMYTLFGEG 833
+ DENDN PVF Y+ E ++ G ++ ++A D D G + F+ + G
Sbjct: 424 VVDENDNAPVFSTNIYKASFEETNRTGYQMLK---VEAHDVDLDLSGRVSYFIRNVTGAD 480
Query: 834 KE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK 890
+ F + + +GV++ LD E+ + + A D G LSS A + I + D NDN
Sbjct: 481 VDAYFSIHQTSGVIR-AQHRLDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVNDNY 539
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
P + + V +N G + E+ +D F + G
Sbjct: 540 PVIKEPKPRKGV-ASLSVPVNADKGEIVTEL------GTHLDGTAASFPVDPRTRSGFLA 592
Query: 951 IKLNALDLDSGLNGQIRY 968
+ A D DSG NG + Y
Sbjct: 593 STIKAEDADSGPNGALSY 610
Score = 68.1 bits (159), Expect = 2e-09
Identities = 122/435 (28%), Positives = 178/435 (40%), Gaps = 66/435 (15%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVI---SGA-GIYQVTIYIEDENDNPPVFE 788
A DG + TQ LDRE ++ R + + E V+ SGA +V + + D+ND+ P F
Sbjct: 50 ARDGVLATQGRLDRE--ELCRGSDLCEVAFSVLYRKSGAMNCLRVRVEVMDQNDHSPQFP 107
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV---DENTGV 845
+A + I E + + I ++ +A D D G N L Y+L DV E T
Sbjct: 108 NAEQDVEISEIAGLRMRIPLE---RAVDPDAGPNGLQTYSLSVNRYFALDVTVGPEGTKQ 164
Query: 846 VKF-IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ I LDRE + LSLVA D G S + + I D NDN P F E+S
Sbjct: 165 AELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTF----EDSAP 220
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
+ E N G TII +K A D DQ +N ++ L
Sbjct: 221 TV--ELPENTARGTTIISLK-----ATDPDQ------------------GVNG-EVVYSL 254
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE---SEFRLNISA 1019
+ + E + + P + +A +L+ + + + V+ AR P + +L+I
Sbjct: 255 SKHTQPEVQRLIAVDP-QTAAVSLKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKL 313
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
LD +NDN + R+ FP V E L V DAD GQN
Sbjct: 314 LD---VNDN-APRILADWDRSSFP-------GPTVLEGAPKDTFLSLVTVLDADSGQNGK 362
Query: 1080 LTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
+ Q + PF + + G + NG LDRE Y LT++A+D G
Sbjct: 363 VK--AQILEGSGPFSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYG-DPPLSSVKH 419
Query: 1137 XXXXXXDVNDNSPKF 1151
D NDN+P F
Sbjct: 420 MSVQVVDENDNAPVF 434
Score = 68.1 bits (159), Expect = 2e-09
Identities = 91/404 (22%), Positives = 161/404 (39%), Gaps = 36/404 (8%)
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVIN-------ERHGHVIVARSLPPESE 1012
+GL +I E + P+ L +L V RYF ++ + +++ R L E +
Sbjct: 119 AGLRMRIPLERAVDPDAGPNGLQTYSLSVNRYFALDVTVGPEGTKQAELVIIRELDREVQ 178
Query: 1013 FRLNIS--ALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
+++S A D G+ + + + V ++D ND+ P F+ + + E + +
Sbjct: 179 DSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLK 238
Query: 1069 ATDADFGQNANLTYFI----QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
ATD D G N + Y + QP L + P T +S+ LD E + Y + V ARD
Sbjct: 239 ATDPDQGVNGEVVYSLSKHTQPEVQRL-IAVDPQTAAVSLKAPLDYEVQTSYEVVVEARD 297
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA 1184
G DVNDN+P+ A + + P E + + + ++ V A
Sbjct: 298 RGPNAIPAYCKLHIKLL-DVNDNAPRILADWDRSSFPGPTVLEGAPKD-TFLSLVTVLDA 355
Query: 1185 TIEENAPIGTTVAKVFAN-DTDFIGNGNGLILYSLPQRKNQ----------QNLGLPSLS 1233
+N + + + + GN I+ + + Q Q+ G P LS
Sbjct: 356 DSGQNGKVKAQILEGSGPFSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLS 415
Query: 1234 STAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMR 1291
S + V V D E + PVF + Y+ EE +++ + + + ++
Sbjct: 416 SVKHMSVQVVD-----ENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVS 470
Query: 1292 YYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
Y+I N D+ F I +G + D E ++ IV A
Sbjct: 471 YFIRNVTGADVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVEA 514
Score = 66.1 bits (154), Expect = 7e-09
Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 12/182 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLD-SVNGSLFLEKELDLDAEHNLQANTFV-LQVQ 277
A+D D G Y L + + F+LD +V + EL + E + + V L +
Sbjct: 130 AVDPDAGPNGLQTYSL---SVNRYFALDVTVGPEGTKQAELVIIRELDREVQDSVDLSLV 186
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P ++ + + + D NDN P FE + + EN G +++ + ATD DQG
Sbjct: 187 AWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGV 246
Query: 338 NGEFTYQLD-----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
NGE Y L + + ++DP++ ++++ LD E +S + V A++ P+ +
Sbjct: 247 NGEVVYSLSKHTQPEVQRLIAVDPQTAAVSLK--APLDYEVQTSYEVVVEARDRGPNAIP 304
Query: 393 TF 394
+
Sbjct: 305 AY 306
Score = 53.6 bits (123), Expect = 4e-05
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQV 276
+ +D D G ++ +++ G+ FSL + G + + LD E Q + L +
Sbjct: 350 VTVLDADSGQNGKVKAQILEGSGP--FSLKHMQGGNYKIVTNGTLDRE---QVTWYNLTL 404
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A +P ++ + ++++D NDN P F + Y S E G+ +L+V A D D
Sbjct: 405 LAQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLD 464
Query: 337 ENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSS 376
+G +Y + + GA FSI SG +R Q LD E S
Sbjct: 465 LSGRVSYFIRNVTGADVDAYFSIHQTSG--VIRAQHRLDYEESRS 507
Score = 53.2 bits (122), Expect = 5e-05
Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 16/178 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D GV + Y L ++L ++D ++ L+ LD + + ++ +
Sbjct: 237 LKATDPDQGVNGEVVYSLSKHTQPEVQRLIAVDPQTAAVSLKAPLDYEVQ-----TSYEV 291
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD-----FYNISIVENLPNGFSVLQVM 329
V+A A ++ I+LLD+NDN P D F +++E P + V
Sbjct: 292 VVEARDRGPNAIPAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVT 351
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSIDPRSG--WLTVRNQTVLDREAHSSLRMKVYAKE 385
D D G+NG+ Q+ + G FS+ G + V N T LDRE + + + A++
Sbjct: 352 VLDADSGQNGKVKAQILEGSGPFSLKHMQGGNYKIVTNGT-LDREQVTWYNLTLLAQD 408
Score = 41.9 bits (94), Expect = 0.13
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G L Y + GN +LF L G LF ++ L F L +
Sbjct: 595 IKAEDADSGPNGALSYRIAKGNHNRLFWLHEATGQLF----VNATNATQLIGQNFKLDIA 650
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNL 303
S + +P T +E+ ++L D+L
Sbjct: 651 VSDMGSPRLTTTMTLEVTFINLRDHL 676
Score = 38.3 bits (85), Expect = 1.6
Identities = 28/105 (26%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G ++K+ A D+D L+G++ Y + +V YF I++ G +
Sbjct: 450 GYQMLKVEAHDVDLDLSGRVSYFIRN----------VTGADVDAYFSIHQTSGVIRAQHR 499
Query: 1007 LPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
L E + A+D G+ L+ + +V++ V+DVND++PV K+
Sbjct: 500 LDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVNDNYPVIKE 544
Score = 38.3 bits (85), Expect = 1.6
Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 20/148 (13%)
Query: 219 HAIDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
H +D DL + ++G D FS+ +G + + LD + ++++F+ V+
Sbjct: 459 HDVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRAQHRLDYEES---RSHSFI--VE 513
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP-NGFSVLQVMATDKDQG 336
A +P ++ A V+I++ D+NDN P I E P G + L V + D+G
Sbjct: 514 AIDQGHPPLSSSATVQIQVQDVNDNYP---------VIKEPKPRKGVASLSV-PVNADKG 563
Query: 337 E-NGEFTYQLDDPKGAFSIDP--RSGWL 361
E E LD +F +DP RSG+L
Sbjct: 564 EIVTELGTHLDGTAASFPVDPRTRSGFL 591
>UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|Rep:
Ap-cadherin - Asterina pectinifera (Starfish)
Length = 2909
Score = 100 bits (239), Expect = 4e-19
Identities = 130/492 (26%), Positives = 212/492 (43%), Gaps = 53/492 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD-PDLGQNGMVLY 497
L + ++EVT+LD NDN+P F P Y S+ N+ GT + +V A+D D Q G + Y
Sbjct: 1467 LTGYADLEVTVLDENDNSPFF-PELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITY 1525
Query: 498 DLQRTSNLTITSP--FKINPNTGTVSVAESPILEGR----HALFVEASDQPANPSERRYS 551
+S + F+I+ +TG V+V +L+ + L + ASD P SE
Sbjct: 1526 STISSSEIPNDGSGLFQIDGSTGWVTVKSGAVLDREKNDTYTLRIRASDVPN--SEALTD 1583
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYD 609
+ ++V + P F+G PY V +G +V ++ V DA +V +
Sbjct: 1584 AIIQILDVN-------DNAPVFVGGPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFG 1636
Query: 610 LLHGYEEGVPFAVEE---RSGVITVVDDLSRYNRP--MYDFEAVALQENA--NLSIVTNA 662
++ G G V + G+I + L Y P +Y + + +N+ T
Sbjct: 1637 IIGGNVGGSFEIVADPLTLIGIIRIARPLD-YESPNKLYTL-TITVDDNSGPGSQSQTTI 1694
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTN-MSSIYGNGTGNVRFL- 719
T+ V+DVND + + +V E+ G +IG + ++ + ++G T ++
Sbjct: 1695 TIDVLDVNDVAPTFNPAEY--VSANVLESVDVGTSIGTVSASDPEAGVFGQFTFSIDPAS 1752
Query: 720 ----IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+ + ++++ I + T KPLDRE + + +T+ A + GV G + +
Sbjct: 1753 DPDGLFSIEEIS-PIGAVRRADVKTAKPLDRENVETHVLTLRAT-DLGVPPLTGYATLNL 1810
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FG 831
++D ND PP F Y I EN E++ I A D D F +
Sbjct: 1811 TLDDVNDTPPTFA-TDYRPTIKENL---AEVQFVGYISAKDEDPTGGPPFTLVVEPNTDT 1866
Query: 832 EGKEMFDVDENTGVVKFIGD---SLDREKKIMYK--LSLVARDTGGLSSEAELIIMIGDE 886
+ FDV TG I S DRE + Y + + R G S LI+ I DE
Sbjct: 1867 DSFTWFDVGGTTGNNLSISSKAISFDRETQATYSIPIRITDRAPNGNSGVNYLIVEIEDE 1926
Query: 887 NDNKPEFNQIEE 898
NDN P F +E
Sbjct: 1927 NDN-PHFGTTKE 1937
Score = 97.5 bits (232), Expect = 2e-18
Identities = 114/479 (23%), Positives = 197/479 (41%), Gaps = 26/479 (5%)
Query: 429 TENIEYYDE-QLMSFVNVE-VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T +E YD+ +S + + V + D ND P F +N + + + ++ +V+A D
Sbjct: 1132 TLQVEAYDDGNRLSILGTQRVNVQDVNDETPQFPVTNFF-VAFPEDVDAPFLVTRVQAED 1190
Query: 487 PDLGQN-GMVLYDLQRTSNLTITSPFKINPNTG--TVSVAESPILEGRHALFVEASD-QP 542
D + Y L +T + F+I+P TG T ++ E +++ V A+D P
Sbjct: 1191 ADTETAFKTITYSLDQT--FSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQVIATDGAP 1248
Query: 543 AN-PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF 601
++ PS + + + + K + P P F Y + + +G V Q+ D
Sbjct: 1249 SSLPSAGGPNKGYLRVVINVVDKNDNP--PVFDRPMYTRTIREDEPVGYEVIQVTATDV- 1305
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
+ + + L+ G F V+ +G I++ L + Y + N L++ +
Sbjct: 1306 DPDSIPRYLITANNTGGAFEVDPATGAISIASPLDYETQREY---WLMYSANDGLNVAST 1362
Query: 662 AT-VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ + +VNDE+ ++ V EN + T + ++R+ +
Sbjct: 1363 VIRIQLENVNDEKPEFELPVYTA---EVSENDPNVPRQLLQVTAVDGDADAVQADIRYSL 1419
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTIYIED 779
T A G I + LDRE ++++ V A G S G + + + D
Sbjct: 1420 EGTGAGTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLD 1479
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE----GTNALFMYTLFGEGKE 835
ENDN P F Y G + ENS GT + I D ++ + + + +G
Sbjct: 1480 ENDNSPFFPELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSG 1539
Query: 836 MFDVDENTG-VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+F +D +TG V G LDREK Y L + A D + + II I D NDN P F
Sbjct: 1540 LFQIDGSTGWVTVKSGAVLDREKNDTYTLRIRASDVPNSEALTDAIIQILDVNDNAPVF 1598
Score = 89.8 bits (213), Expect = 5e-16
Identities = 128/534 (23%), Positives = 217/534 (40%), Gaps = 55/534 (10%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+ D + S VE+ + D NDN P+F N Y S+ +A +GT + KV+A D D G
Sbjct: 819 NVTATDGKYTSDAEVEIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKG 878
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSER 548
N + YD+ ++N PF I+ TG +S + E + V A D P +
Sbjct: 879 VNAEIAYDIAGSNN-----PFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPGSIFSN 933
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
+ ++T+ +T N+P P Y + + + ++ V DA +
Sbjct: 934 Q-GFCIITVNIT-DVNDNRPTFP---LEDYVVIISNTAPQFAPILKVEVEDADLPTPAGF 988
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+ V F + + +G I V DLS Y+ ++F+ A E+ +N V V+
Sbjct: 989 TYGLTTQNPVLFEINQ-NGEIFPVADLSVYDDNTFNFKVEA--EDGPNRAKSNVQVKVLA 1045
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT------GNVRFLIAN 722
++ P I ++ S IG + S GNG G + +
Sbjct: 1046 TGVDQPPEWVSTF-PDITVMENISINDVIGTL---QAQSRSGNGVGYRVVQGQIPQTNSE 1101
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
Q ++ + ++ PLD E Y + V A + +S G +V ++D ND
Sbjct: 1102 GQFAVQNVGDSMIANLYISAPLDYETTKFYTLQVEAYDDGNRLSILGTQRVN--VQDVND 1159
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTL---FGEGKEMFD 838
P F + F+ + + ++A DAD E Y+L F + + F
Sbjct: 1160 ETPQFPVTNF--FVAFPEDVDAPFLVTR-VQAEDADTETAFKTITYSLDQTFSDA-QYFR 1215
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARD--------TGGLS-SEAELIIMIGDENDN 889
+D TG + DRE + Y + ++A D GG + ++I + D+NDN
Sbjct: 1216 IDPTTGDLTST-IKFDRESEDSYSVQVIATDGAPSSLPSAGGPNKGYLRVVINVVDKNDN 1274
Query: 890 KPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPEN 943
P F + R RE + G+ +I+V + +D D + P +LI N
Sbjct: 1275 PPVF---DRPMYTRTIREDE---PVGYEVIQVTATD---VDPDSI-PRYLITAN 1318
Score = 87.4 bits (207), Expect = 3e-15
Identities = 89/328 (27%), Positives = 149/328 (45%), Gaps = 36/328 (10%)
Query: 80 YLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT 139
YL V + + D NDN P+F Y T+ E P G + + P ++PR L
Sbjct: 1261 YLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYEVIQVTATDVDPD-----SIPRYLI 1315
Query: 140 IFKDIR-AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV----LLLRKVLDYDAGD 194
+ AF+ D P T + + ++ + S++ + ++R L+ +
Sbjct: 1316 TANNTGGAFEVD-PATGAISIASPLDYETQREYWLMYSANDGLNVASTVIRIQLENVNDE 1374
Query: 195 K-EFQLVIMAS-----GKRIHKEILFPEPIHAIDQDL-GVGATLRYELISGNDRKLFSLD 247
K EF+L + + + +++L + A+D D V A +RY L F++D
Sbjct: 1375 KPEFELPVYTAEVSENDPNVPRQLL---QVTAVDGDADAVQADIRYSLEGTGAGTTFTID 1431
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP--LKTAQARVEIELLDLNDNLPE 305
+V G + L + LD ++ + + L V+A+ T A +E+ +LD NDN P
Sbjct: 1432 AVTGQITLTEMLDRES-----VSIWKLLVKATDGGGTGTSLTGYADLEVTVLDENDNSPF 1486
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATD-KDQGENGEFTYQL-------DDPKGAFSIDPR 357
F Y S+ EN P G V+QV A D D + G TY +D G F ID
Sbjct: 1487 FPELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSGLFQIDGS 1546
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+GW+TV++ VLDRE + + +++ A +
Sbjct: 1547 TGWVTVKSGAVLDREKNDTYTLRIRASD 1574
Score = 85.0 bits (201), Expect = 1e-14
Identities = 54/145 (37%), Positives = 72/145 (49%), Gaps = 5/145 (3%)
Query: 1009 PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK-TWYNFNVEEAQYTRRVLGKV 1067
PE+ +R N++A DG +D V + V D+ND+ P+F Y ++ E+ L KV
Sbjct: 812 PEASYRFNVTATDGKYTSD-AEVEIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKV 870
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN-G 1126
ATDAD G NA + Y I S+ PF I +TG +S LDRET + V A+DN G
Sbjct: 871 QATDADKGVNAEIAYDIAGSNN--PFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPG 928
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKF 1151
DVNDN P F
Sbjct: 929 SIFSNQGFCIITVNITDVNDNRPTF 953
Score = 78.6 bits (185), Expect = 1e-12
Identities = 134/535 (25%), Positives = 218/535 (40%), Gaps = 57/535 (10%)
Query: 442 FVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
++ V + ++D NDN PVF +Y +++ + VG + +V A D D + + Y +
Sbjct: 1261 YLRVVINVVDKNDNPPVF-DRPMYTRTIREDEPVGYEVIQVTATDVD--PDSIPRYLI-- 1315
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
T+N T F+++P TG +S+A E + ++ S AN S V+ I++
Sbjct: 1316 TANNT-GGAFEVDPATGAISIASPLDYETQREYWLMYS---ANDGLNVAS-TVIRIQL-- 1368
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSN-VGIGTSVGQIRVNDAFE---QNDVSYDLLHGYEEG 617
+ + P+F Y V N + + Q+ D Q D+ Y L G G
Sbjct: 1369 --ENVNDEKPEFELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSL-EGTGAG 1425
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ---ENANLSIVTNATVHVVDVNDERG 674
F ++ +G IT+ + L R + ++ A +L+ + V V+D ND
Sbjct: 1426 TTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDENDNSP 1485
Query: 675 VLLKGAHSPIIFHVKENSAGAA-IGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA-- 731
+ + V ENS G + Q+ T + N G + + + ++ +D +
Sbjct: 1486 FFPELEYRG---SVPENSPGGTPVMQV--TAIDYDDPNQFGRITYSTISSSEIPNDGSGL 1540
Query: 732 IAEDG-----TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
DG T+ + LDREK D Y + + A V + + I I D NDN PV
Sbjct: 1541 FQIDGSTGWVTVKSGAVLDREKNDTYTLRIRAS---DVPNSEALTDAIIQILDVNDNAPV 1597
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG---EGKEMFDVDENT 843
F Y + E +G + + TDAD N + + G G D T
Sbjct: 1598 FVGGPYATSVEETQPVGATVWE---VSVTDADVDFNEEVQFGIIGGNVGGSFEIVADPLT 1654
Query: 844 --GVVKFIGDSLDREK-KIMYKLSLVARDTGGLSSEAELIIMIG--DENDNKPEFNQIE- 897
G+++ I LD E +Y L++ D G S+++ I I D ND P FN E
Sbjct: 1655 LIGIIR-IARPLDYESPNKLYTLTITVDDNSGPGSQSQTTITIDVLDVNDVAPTFNPAEY 1713
Query: 898 --ENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGP---LFLIPENIPIG 947
N + T + GT + E +F +D LF I E PIG
Sbjct: 1714 VSANVLESVDVGTSI-GTVSASDPEAGVFGQFTFSIDPASDPDGLFSIEEISPIG 1767
Score = 74.5 bits (175), Expect = 2e-11
Identities = 120/459 (26%), Positives = 184/459 (40%), Gaps = 51/459 (11%)
Query: 908 TKLNGTAGF--TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN-G 964
T L G A T+++ + F +++ G +PEN P GT ++++ A+D D G
Sbjct: 1465 TSLTGYADLEVTVLDENDNSPFFPELEYRGS---VPENSPGGTPVMQVTAIDYDDPNQFG 1521
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
+I Y S IP ++ +V + G V+ + L I A D N
Sbjct: 1522 RITYSTISSSEIPNDGSGLFQIDGSTGWV-TVKSGAVLDREK---NDTYTLRIRASDVPN 1577
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+ + DVND+ PVF Y +VEE Q + +V TDAD N + + I
Sbjct: 1578 SEALTDAIIQILDVNDNAPVFVGGPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFGI 1637
Query: 1085 QPSDTDLPFEI--SPLT--GVLSVNGELDRETEDK-YILTVVARDNGXXXXXXXXXXXXX 1139
+ FEI PLT G++ + LD E+ +K Y LT+ DN
Sbjct: 1638 IGGNVGGSFEIVADPLTLIGIIRIARPLDYESPNKLYTLTITVDDN-SGPGSQSQTTITI 1696
Query: 1140 XXXDVNDNSPKF----YAFDELLE------------WKHPEADELSNHNFE-SVMMIPVY 1182
DVND +P F Y +LE PEA F P
Sbjct: 1697 DVLDVNDVAPTFNPAEYVSANVLESVDVGTSIGTVSASDPEAGVFGQFTFSIDPASDPDG 1756
Query: 1183 KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTV 1242
+IEE +PIG V + + N + + L R +LG+P L+ A L +T+
Sbjct: 1757 LFSIEEISPIG-AVRRADVKTAKPLDREN-VETHVLTLRAT--DLGVPPLTGYATLNLTL 1812
Query: 1243 ADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS-LNLTEHYENFKMRYYILNE--ND 1299
DV +D P + Y I+EN+ A V+ V ++ + + ++ E D
Sbjct: 1813 DDV------NDTPPTFATDYRPTIKENL-AEVQFVGYISAKDEDPTGGPPFTLVVEPNTD 1865
Query: 1300 TDIRRTFVIDPRNGTLYLVRSP----DREVKDTYEVIVR 1334
TD F + G + S DRE + TY + +R
Sbjct: 1866 TDSFTWFDVGGTTGNNLSISSKAISFDRETQATYSIPIR 1904
Score = 68.5 bits (160), Expect = 1e-09
Identities = 117/468 (25%), Positives = 189/468 (40%), Gaps = 58/468 (12%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V V L D ND PVF+ ++ + + +A +G +IG V A D D + + + +Q +S
Sbjct: 736 VWVYLTDVNDEGPVFLNTDGSVYYIDEDAPLGYIIGTVYASDAD--KTDTITFGIQGSST 793
Query: 505 LTITSPFKINPNTGTVS-VAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
F+I+P TG +S + + E + V A+D + S A V I+V
Sbjct: 794 ------FQIDPQTGVISRIGTGNLPEASYRFNVTATD------GKYTSDAEVEIQV-NDI 840
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFA 621
N P PD Y + + IGT + +++ DA + +++YD+ PF
Sbjct: 841 NDNTPIFPDCNS--YAPSISESAAIGTFLIKVQATDADKGVNAEIAYDIAGSNN---PFT 895
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-----ATVHVVDVNDERGVL 676
++ +G I+ D L R P D V Q+N SI +N TV++ DVND R
Sbjct: 896 IDAVTGDISTQDPLDRETTPTIDI-VVTAQDNPG-SIFSNQGFCIITVNITDVNDNRPTF 953
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+ II + A ++ ++ + G G + Q V I ++G
Sbjct: 954 PLEDYVVIISNTAPQFAPILKVEVEDADLPTPAGFTYG-----LTTQNPVL--FEINQNG 1006
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
IF L + + V AE G QV + + D PP + + +
Sbjct: 1007 EIFPVADLSVYDDNTFNFKVEAE--DGPNRAKSNVQVKV-LATGVDQPPEWVSTFPDITV 1063
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS---- 852
MEN I ++++I A + Y + +G+ E V+ +GDS
Sbjct: 1064 MEN------ISINDVIGTLQAQSRSGNGVGYRVV-QGQIPQTNSEGQFAVQNVGDSMIAN 1116
Query: 853 ------LDREKKIMYKLSLVARDTGG-LSSEAELIIMIGDENDNKPEF 893
LD E Y L + A D G LS + + D ND P+F
Sbjct: 1117 LYISAPLDYETTKFYTLQVEAYDDGNRLSILGTQRVNVQDVNDETPQF 1164
Score = 66.1 bits (154), Expect = 7e-09
Identities = 98/402 (24%), Positives = 146/402 (36%), Gaps = 33/402 (8%)
Query: 1013 FRLNISALDGGNLNDNISV-RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
+ L + A D GN + RV V+DVND P F T + E ++ +V A D
Sbjct: 1131 YTLQVEAYDDGNRLSILGTQRVNVQDVNDETPQFPVTNFFVAFPEDVDAPFLVTRVQAED 1190
Query: 1072 ADFGQN-ANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
AD +TY + + +D F I P TG L+ + DRE+ED Y + V+A D
Sbjct: 1191 ADTETAFKTITYSLDQTFSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQVIATDGAPSS 1250
Query: 1130 XXXX------XXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYK 1183
D NDN P FD + + DE + V V
Sbjct: 1251 LPSAGGPNKGYLRVVINVVDKNDNPP---VFDRPMYTRTIREDEPVGYEVIQVTATDVDP 1307
Query: 1184 ATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
+I F D G I L ++ + S + + TV
Sbjct: 1308 DSIPRYLITANNTGGAFEVDP---ATGAISIASPLDYETQREYWLMYSANDGLNVASTVI 1364
Query: 1244 DVPDEVEMSDKPVFISRYYELEIEEN-VNAPVELVSLNLTEHYENFKMRYYILNENDTDI 1302
+ E +KP F Y E+ EN N P +L+ + + + + T
Sbjct: 1365 RIQLENVNDEKPEFELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSLEGTGA 1424
Query: 1303 RRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKY 1362
TF ID G + L DRE ++++V+A +T Y
Sbjct: 1425 GTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATD--------------GGGTGTSLTGY 1470
Query: 1363 DVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+ V + D NDNSP F ++P +P G VMQ+
Sbjct: 1471 -ADLEVTVLDENDNSPFFP--ELEYRGSVPENSPGGTPVMQV 1509
Score = 66.1 bits (154), Expect = 7e-09
Identities = 80/313 (25%), Positives = 131/313 (41%), Gaps = 32/313 (10%)
Query: 606 VSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT----- 660
++Y L + + F ++ +G +T R + Y + +A + A S+ +
Sbjct: 1200 ITYSLDQTFSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQVIAT-DGAPSSLPSAGGPN 1258
Query: 661 ----NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
++VVD ND V + ++ I ++ G + Q+ T++
Sbjct: 1259 KGYLRVVINVVDKNDNPPVFDRPMYTRTIR--EDEPVGYEVIQVTATDVDP-----DSIP 1311
Query: 717 RFLI-ANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
R+LI AN ++ A G I PLD E + Y + A V S + I
Sbjct: 1312 RYLITANNTGGAFEVDPAT-GAISIASPLDYETQREYWLMYSANDGLNVASTV----IRI 1366
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEGK 834
+E+ ND P FE Y + EN + + A D D + A Y+L G G
Sbjct: 1367 QLENVNDEKPEFELPVYTAEVSENDPNVPRQLLQ--VTAVDGDADAVQADIRYSLEGTGA 1424
Query: 835 -EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG----LSSEAELIIMIGDENDN 889
F +D TG + + + LDRE ++KL + A D GG L+ A+L + + DENDN
Sbjct: 1425 GTTFTIDAVTGQIT-LTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDENDN 1483
Query: 890 KPEFNQIEENSKV 902
P F ++E V
Sbjct: 1484 SPFFPELEYRGSV 1496
Score = 65.7 bits (153), Expect = 9e-09
Identities = 96/399 (24%), Positives = 164/399 (41%), Gaps = 49/399 (12%)
Query: 1022 GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
GG + V + V D ND+ PVF + Y + E + + +V ATD D ++
Sbjct: 1255 GGPNKGYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYEVIQVTATDVD--PDSIPR 1312
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
Y I ++T FE+ P TG +S+ LD ET+ +Y L A D
Sbjct: 1313 YLITANNTGGAFEVDPATGAISIASPLDYETQREYWLMYSANDG----LNVASTVIRIQL 1368
Query: 1142 XDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA 1201
+VND P+F EL + ++ N + + + V A I ++ A
Sbjct: 1369 ENVNDEKPEF----ELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSLEGTGA 1424
Query: 1202 NDTDFIGNGNGLILYSLPQRKNQQNLGLPSL-------SSTAILMVTVADVPDEV--EMS 1252
T I G I +L + +++++ + L T + AD+ V E
Sbjct: 1425 GTTFTIDAVTGQI--TLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDEND 1482
Query: 1253 DKPVFISRYYELEIEENV--NAPV-ELVSLNLTEHYENFKMRYYILNEND--TDIRRTFV 1307
+ P F Y + EN PV ++ +++ + + ++ Y ++ ++ D F
Sbjct: 1483 NSPFFPELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSGLFQ 1542
Query: 1308 IDPRNGTLYLVRSP--DREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
ID G + + DRE DTY + +RA ++P+ E +T
Sbjct: 1543 IDGSTGWVTVKSGAVLDREKNDTYTLRIRAS------DVPNS---------EALT----D 1583
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
+++I DVNDN+P F G P T++ T P G V ++
Sbjct: 1584 AIIQILDVNDNAPVFVGG--PYATSVEETQPVGATVWEV 1620
Score = 64.1 bits (149), Expect = 3e-08
Identities = 128/475 (26%), Positives = 186/475 (39%), Gaps = 78/475 (16%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNF-NVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
L+ + V V V D+ND P F++ Y+F NV E T +G V ATD D N LTY
Sbjct: 627 LSTTVRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIGTVAATDCDADPNNILTYS 686
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETED-KYILTVVARDNGXXXXXXXXXXXXXXXX 1142
+ + D F + GVL ELD + D Y L RD
Sbjct: 687 LIGAQAD-KFRLDS-QGVLYAATELDYDVGDGSYELEAQVRDQ---AGGADTATVWVYLT 741
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
DVND P F D VY I+E+AP+G + V+A+
Sbjct: 742 DVNDEGPVFLNTDG-----------------------SVY--YIDEDAPLGYIIGTVYAS 776
Query: 1203 D---TDFIGNG-NGLILYSL-PQRKNQQNLG---LPSLSSTAILMVT----VADVPDEVE 1250
D TD I G G + + PQ +G LP S + T +D E++
Sbjct: 777 DADKTDTITFGIQGSSTFQIDPQTGVISRIGTGNLPEASYRFNVTATDGKYTSDAEVEIQ 836
Query: 1251 MSD----KPVFIS-RYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIR 1303
++D P+F Y I E+ L+ + T+ + N ++ Y I N+
Sbjct: 837 VNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKGVNAEIAYDIAGSNN---- 892
Query: 1304 RTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYD 1363
F ID G + DRE T +++V A+ + P I+ +G
Sbjct: 893 -PFTIDAVTGDISTQDPLDRETTPTIDIVVTAQ------DNPGSIFS-----NQGF---- 936
Query: 1364 VKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPT-ASRTVRADT 1422
+ V I DVNDN P F V I TAP +++++ PT A T T
Sbjct: 937 CIITVNITDVNDNRPTFP--LEDYVVIISNTAPQFAPILKVEVEDADLPTPAGFTYGLTT 994
Query: 1423 DELVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVA 1477
V FE ++ NG P A D + + +++ E P A V V+V+A
Sbjct: 995 QNPVLFE-INQNGEIFPVA-DLSVYDDNTFNFKVEAEDGPNRAKSNVQ--VKVLA 1045
Score = 62.5 bits (145), Expect = 9e-08
Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 3/105 (2%)
Query: 287 TAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
T+ A VEI++ D+NDN P F + + Y SI E+ G +++V ATD D+G N E Y +
Sbjct: 828 TSDAEVEIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKGVNAEIAYDI 887
Query: 346 DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
F+ID +G + Q LDRE ++ + V A++ S+
Sbjct: 888 AGSNNPFTIDAVTG--DISTQDPLDRETTPTIDIVVTAQDNPGSI 930
Score = 62.1 bits (144), Expect = 1e-07
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 5/138 (3%)
Query: 230 TLRYELISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL---NNPL 285
T+ Y L +D + F +D G L + D ++E + S L P
Sbjct: 1199 TITYSLDQTFSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQVIATDGAPSSLPSAGGPN 1258
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
K RV I ++D NDN P F+ Y +I E+ P G+ V+QV ATD D +
Sbjct: 1259 K-GYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYEVIQVTATDVDPDSIPRYLITA 1317
Query: 346 DDPKGAFSIDPRSGWLTV 363
++ GAF +DP +G +++
Sbjct: 1318 NNTGGAFEVDPATGAISI 1335
Score = 61.3 bits (142), Expect = 2e-07
Identities = 121/487 (24%), Positives = 203/487 (41%), Gaps = 55/487 (11%)
Query: 433 EYYDEQLMSFVNVEVTLLDAND-----NNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
E+Y L + VN EV + + + PVF S+ + +S+ N+ VGT+ G V A D
Sbjct: 194 EFYKLTLEAVVNDEVAMTEVQIWVLGLHPPVFAFSS-FIYSIAENSPVGTIAGTVFATDE 252
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSE 547
D+G+NG V Y L L + F + +G V+V E P G + + V A D A
Sbjct: 253 DMGENGRVTYHL-----LKLNRYFTVGQESGLVTVTE-PTPVGEYTMQVVARD--AGTPF 304
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAP-YEFWVGSNVGIGTSVGQIRVNDAFEQNDV 606
+ + + I V + P D M AP Y+ + ++ VN+ N V
Sbjct: 305 QESAPVPLQISVISSSSNMIPYGNDMMFAPDYKPSKRFRREV-LPEERVPVNEDTAINTV 363
Query: 607 SYDL--LHGYEE----GVP---FAVEERSGVITVVDDLSRYNRPMYDFEA-VALQENANL 656
+ + L+ + G P F + E +G + ++D L+ +++FE + EN +
Sbjct: 364 IFTVSSLNDTDRFAYVGTPNPLFGLNETTGEVKLLDQLNFEQATVHEFEVEITNVENTDK 423
Query: 657 SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+ V +VN+ + G + P I V ++ A IFH S G+ +V
Sbjct: 424 RDTQRIIIEVQNVNEPPQWEI-GVY-PYIEVVPVDAPTGA--SIFHLRASDPEGS---DV 476
Query: 717 RFLIANQQDVTDDIAIAEDGTIFT--QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
RF + N E G I T + ++ Y ++V A+ G A +V
Sbjct: 477 RFYL-NSGGSGLFTVDEESGWIKTSLSEGQGYQQGQKYILSVYAQDENGSSIPA---EVN 532
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
I+ +PP F Y + E IG + N+I DA +N + L
Sbjct: 533 IF---GGSHPPQFTQEVYNVAVTE-EVIGEQ----NVID-IDAFSFSNVAVTFALLNSET 583
Query: 835 EM----FDVDENTGVVKFIGDSLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDEND 888
+D ++G +K + + +DRE Y L + A + GLS+ + + + D ND
Sbjct: 584 NQPIPRHSIDPSSGQIKLL-EKVDREVLDSYFLEVQATEDVQDGLSTTVRVNVEVTDIND 642
Query: 889 NKPEFNQ 895
P+F +
Sbjct: 643 CVPKFER 649
Score = 60.1 bits (139), Expect = 5e-07
Identities = 46/168 (27%), Positives = 83/168 (49%), Gaps = 17/168 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL--DSVN--GSLFLEKELDLDAEHNLQANTFV 273
+ D D+ +++ +I GN F + D + G + + + LD ++ + L +
Sbjct: 1620 VSVTDADVDFNEEVQFGIIGGNVGGSFEIVADPLTLIGIIRIARPLDYESPNKL----YT 1675
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATD 332
L + + P +Q + I++LD+ND P F ++ + +++E++ G S+ V A+D
Sbjct: 1676 LTITVDDNSGPGSQSQTTITIDVLDVNDVAPTFNPAEYVSANVLESVDVGTSIGTVSASD 1735
Query: 333 KDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTV-----LDRE 372
+ G G+FT+ +D DP G FSI+ S VR V LDRE
Sbjct: 1736 PEAGVFGQFTFSIDPASDPDGLFSIEEISPIGAVRRADVKTAKPLDRE 1783
Score = 59.3 bits (137), Expect = 8e-07
Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 18/188 (9%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
E I D+ + RY + + N F +D G++ + LD + + + L
Sbjct: 1296 EVIQVTATDVDPDSIPRYLITANNTGGAFEVDPATGAISIASPLDYETQRE-----YWLM 1350
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPN-GFSVLQVMATDKD 334
A N+ L A + I+L ++ND PEFE+ Y + EN PN +LQV A D D
Sbjct: 1351 YSA---NDGLNVASTVIRIQLENVNDEKPEFELPVYTAEVSENDPNVPRQLLQVTAVDGD 1407
Query: 335 -QGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE---TNP 388
+ Y L+ F+ID +G +T+ +LDRE+ S ++ V A + T
Sbjct: 1408 ADAVQADIRYSLEGTGAGTTFTIDAVTGQITLTE--MLDRESVSIWKLLVKATDGGGTGT 1465
Query: 389 SVVGTFAD 396
S+ G +AD
Sbjct: 1466 SLTG-YAD 1472
Score = 58.8 bits (136), Expect = 1e-06
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F ++ G + +A L E+ E+ L SA DG N+ + +R+ +++VND P F+
Sbjct: 1324 FEVDPATGAISIASPLDYETQREYWLMYSANDGLNVASTV-IRIQLENVNDEKPEFELPV 1382
Query: 1050 YNFNVEEAQ-YTRRVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y V E R L +V A D D A++ Y ++ + F I +TG +++
Sbjct: 1383 YTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSLEGTGAGTTFTIDAVTGQITLTEM 1442
Query: 1108 LDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE+ + L V A D G D NDNSP F
Sbjct: 1443 LDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDENDNSPFF 1487
Score = 57.6 bits (133), Expect = 2e-06
Identities = 74/320 (23%), Positives = 126/320 (39%), Gaps = 20/320 (6%)
Query: 33 SVILAQSIDSLVDSDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQISA---YLSVTVYIED 89
S+I AQ+ +DS Q V+ D+D GD + A + + +V VY+ D
Sbjct: 686 SLIGAQADKFRLDS---QGVLYAATELDYDVGDGSYELEAQVRDQAGGADTATVWVYLTD 742
Query: 90 VNDNVPIFLDTPYHVT-VDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFD 148
VND P+FL+T V +DE P G + + TI + T D +
Sbjct: 743 VNDEGPVFLNTDGSVYYIDEDAPLGYIIGTVYASDADKTDTITFGIQGSSTFQIDPQTGV 802
Query: 149 RDKPNTPN-SDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDA--GDKEFQLVIMASG 205
+ T N + Y DG + ++ + + + + D D ++
Sbjct: 803 ISRIGTGNLPEASYRFNVTATDGKYTSDAEVE--IQVNDINDNTPIFPDCNSYAPSISES 860
Query: 206 KRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH 265
I ++ + A D D GV A + Y++ N+ F++D+V G + + LD +
Sbjct: 861 AAIGTFLI---KVQATDADKGVNAEIAYDIAGSNNP--FTIDAVTGDISTQDPLDRETTP 915
Query: 266 NLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSV 325
+ S +N + + + D+NDN P F ++ Y + I P +
Sbjct: 916 TIDIVVTAQDNPGSIFSNQ---GFCIITVNITDVNDNRPTFPLEDYVVIISNTAPQFAPI 972
Query: 326 LQVMATDKDQGENGEFTYQL 345
L+V D D FTY L
Sbjct: 973 LKVEVEDADLPTPAGFTYGL 992
Score = 54.8 bits (126), Expect = 2e-05
Identities = 105/408 (25%), Positives = 161/408 (39%), Gaps = 37/408 (9%)
Query: 496 LYDLQRTSNLTITSP-FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
L D R + + +P F +N TG V + + E E +++R + +
Sbjct: 370 LNDTDRFAYVGTPNPLFGLNETTGEVKLLDQLNFEQATVHEFEVEITNVENTDKRDTQRI 429
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY 614
+ IEV N+P + PY V + G S+ +R +D E +DV + L G
Sbjct: 430 I-IEVQNV---NEPPQWEIGVYPYIEVVPVDAPTGASIFHLRASDP-EGSDVRFYLNSG- 483
Query: 615 EEGVPFAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
G+ F V+E SG I T + + Y + +V Q+ SI +VN
Sbjct: 484 GSGL-FTVDEESGWIKTSLSEGQGYQQGQKYILSVYAQDENGSSIPA-------EVN--- 532
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR--FLIANQ---QDVTD 728
+ G+H P N A I N+ I NV F + N Q +
Sbjct: 533 --IFGGSHPPQFTQEVYNVA-VTEEVIGEQNVIDIDAFSFSNVAVTFALLNSETNQPIPR 589
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI-YQVTIYIEDENDNPPVF 787
G I + +DRE D Y + V A + V G +V + + D ND P F
Sbjct: 590 HSIDPSSGQIKLLEKVDREVLDSYFLEVQA--TEDVQDGLSTTVRVNVEVTDINDCVPKF 647
Query: 788 EHATYE-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
E TY ++E T I + ATD D N + Y+L G + F +D + GV+
Sbjct: 648 ERETYSFRNVIETIDTTTPI---GTVAATDCDADPNNILTYSLIGAQADKFRLD-SQGVL 703
Query: 847 KFIGDSLDRE-KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
+ LD + Y+L RD G + A + + + D ND P F
Sbjct: 704 -YAATELDYDVGDGSYELEAQVRDQAGGADTATVWVYLTDVNDEGPVF 750
Score = 54.8 bits (126), Expect = 2e-05
Identities = 76/320 (23%), Positives = 128/320 (40%), Gaps = 22/320 (6%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
+TV I DVNDN P F Y V + P + A I + L P GLT
Sbjct: 939 ITVNITDVNDNRPTFPLEDYVVIISNTAP--QFAPILKVEVEDADLPTPAGFTYGLTTQN 996
Query: 143 DIR-AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV---LDYDAGDKEFQ 198
+ +++ P +D+ V ++ +F +E+ P V + D+ +
Sbjct: 997 PVLFEINQNGEIFPVADLS---VYDDNTFNFKVEAEDGPNRAKSNVQVKVLATGVDQPPE 1053
Query: 199 LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISG-----NDRKLFSLDSVNGSL 253
V + + I + I + G + Y ++ G N F++ +V S+
Sbjct: 1054 WVSTFPDITVMENISINDVIGTLQAQSRSGNGVGYRVVQGQIPQTNSEGQFAVQNVGDSM 1113
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
+ ++ + LQV+A N L + + + D+ND P+F V + +
Sbjct: 1114 IANLYISAPLDYET-TKFYTLQVEAYDDGNRLSILGTQ-RVNVQDVNDETPQFPVTNFFV 1171
Query: 314 SIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVL 369
+ E++ F V +V A D D + TY LD F IDP +G LT +
Sbjct: 1172 AFPEDVDAPFLVTRVQAEDADTETAFKTITYSLDQTFSDAQYFRIDPTTGDLT--STIKF 1229
Query: 370 DREAHSSLRMKVYAKETNPS 389
DRE+ S ++V A + PS
Sbjct: 1230 DRESEDSYSVQVIATDGAPS 1249
Score = 54.0 bits (124), Expect = 3e-05
Identities = 50/193 (25%), Positives = 88/193 (45%), Gaps = 12/193 (6%)
Query: 206 KRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD----- 260
KR +E+L PE +++D + T+ + + S ND F+ LF E
Sbjct: 340 KRFRREVL-PEERVPVNEDTAIN-TVIFTVSSLNDTDRFAYVGTPNPLFGLNETTGEVKL 397
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-ISIVE-N 318
LD + QA +V+ + + N K R+ IE+ ++N+ P++E+ Y I +V +
Sbjct: 398 LDQLNFEQATVHEFEVEITNVENTDKRDTQRIIIEVQNVNEP-PQWEIGVYPYIEVVPVD 456
Query: 319 LPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLR 378
P G S+ + A+D + G + F Y G F++D SGW+ +
Sbjct: 457 APTGASIFHLRASDPE-GSDVRF-YLNSGGSGLFTVDEESGWIKTSLSEGQGYQQGQKYI 514
Query: 379 MKVYAKETNPSVV 391
+ VYA++ N S +
Sbjct: 515 LSVYAQDENGSSI 527
Score = 54.0 bits (124), Expect = 3e-05
Identities = 46/153 (30%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+T+ I + LF +D G + ++ LD E N +T+ L+++AS + N
Sbjct: 1526 STISSSEIPNDGSGLFQIDGSTGWVTVKSGAVLDREKN---DTYTLRIRASDVPNSEALT 1582
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--D 346
A ++I LD+NDN P F Y S+ E P G +V +V TD D N E + +
Sbjct: 1583 DAIIQI--LDVNDNAPVFVGGPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFGIIGG 1640
Query: 347 DPKGAFSI--DPRSGWLTVRNQTVLDREAHSSL 377
+ G+F I DP + +R LD E+ + L
Sbjct: 1641 NVGGSFEIVADPLTLIGIIRIARPLDYESPNKL 1673
Score = 53.2 bits (122), Expect = 5e-05
Identities = 45/162 (27%), Positives = 72/162 (44%), Gaps = 24/162 (14%)
Query: 1243 ADVPDEVEM---SDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNEND 1299
+ +P EV + S P F Y + + E V ++ ++ + N + + +LN
Sbjct: 525 SSIPAEVNIFGGSHPPQFTQEVYNVAVTEEVIGEQNVIDIDAFS-FSNVAVTFALLNSET 583
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
IDP +G + L+ DREV D+Y + V+A EDV +G+
Sbjct: 584 NQPIPRHSIDPSSGQIKLLEKVDREVLDSYFLEVQA----------------TEDVQDGL 627
Query: 1360 TKYDVKVVVRIKDVNDNSPKF---TNGNRPLVTAIPTTAPFG 1398
+ V+V V + D+ND PKF T R ++ I TT P G
Sbjct: 628 ST-TVRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIG 668
Score = 51.6 bits (118), Expect = 2e-04
Identities = 44/143 (30%), Positives = 63/143 (44%), Gaps = 11/143 (7%)
Query: 1010 ESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN-FNVEEAQYTRRVLGKVD 1068
+ + L D D +V V++ DVND PVF T + + ++E ++G V
Sbjct: 715 DGSYELEAQVRDQAGGADTATVWVYLTDVNDEGPVFLNTDGSVYYIDEDAPLGYIIGTVY 774
Query: 1069 ATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
A+DAD + +T+ IQ S T F+I P TGV+S G E Y V A D
Sbjct: 775 ASDAD--KTDTITFGIQGSST---FQIDPQTGVISRIG-TGNLPEASYRFNVTATDG--- 825
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKF 1151
D+NDN+P F
Sbjct: 826 -KYTSDAEVEIQVNDINDNTPIF 847
Score = 50.8 bits (116), Expect = 3e-04
Identities = 73/290 (25%), Positives = 112/290 (38%), Gaps = 38/290 (13%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG-----------------EKAFIFLI 121
A + I DVNDN P+F+ PY +V+E P G E F +
Sbjct: 1580 ALTDAIIQILDVNDNAPVFVGGPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFGIIG 1639
Query: 122 APIGPSLTI---PLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSH 178
+G S I PLT+ + I + R D + PN Y++ DD S
Sbjct: 1640 GNVGGSFEIVADPLTL---IGIIRIARPLDYESPNKL-----YTLTITVDDNSGPGSQSQ 1691
Query: 179 KPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPE--PIHAIDQDLGVGATLRYELI 236
+ + VLD + F S + + + A D + GV + +
Sbjct: 1692 TTITI--DVLDVNDVAPTFNPAEYVSANVLESVDVGTSIGTVSASDPEAGVFGQFTFSID 1749
Query: 237 SGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQ---ANTFVLQVQASQLNNPLKTAQARV 292
+D LFS++ ++ + + D+ L T VL ++A+ L P T A +
Sbjct: 1750 PASDPDGLFSIEEIS-PIGAVRRADVKTAKPLDRENVETHVLTLRATDLGVPPLTGYATL 1808
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
+ L D+ND P F D Y +I ENL V + A D+D FT
Sbjct: 1809 NLTLDDVNDTPPTFATD-YRPTIKENLAEVQFVGYISAKDEDPTGGPPFT 1857
Score = 49.6 bits (113), Expect = 6e-04
Identities = 29/78 (37%), Positives = 38/78 (48%)
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
A E+++ L + P F + SI EN P G V ATD+D GENG TY L
Sbjct: 209 AMTEVQIWVLGLHPPVFAFSSFIYSIAENSPVGTIAGTVFATDEDMGENGRVTYHLLKLN 268
Query: 350 GAFSIDPRSGWLTVRNQT 367
F++ SG +TV T
Sbjct: 269 RYFTVGQESGLVTVTEPT 286
Score = 48.8 bits (111), Expect = 0.001
Identities = 68/266 (25%), Positives = 113/266 (42%), Gaps = 25/266 (9%)
Query: 616 EGVPFAVEERSGVITVVDDLSRY--NRPMYDFEAVALQENANLSIVT---NATVHVVDVN 670
+G F ++ S V D + NRP+ D +L I N ++V VN
Sbjct: 51 QGQSFELDPTSSKYFSVTDSGKLVTNRPLVDLLGSSLTVGIRHRIGDHSWNEQINVRIVN 110
Query: 671 DERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMS-SIYGNGTGNVRFLIANQQDVTD 728
R L A S + ENS G + + + IY G V++ + Q
Sbjct: 111 TGRDSKLHFADSRYQGVISENSPLGEKVRGLSDLRVVVPIYAQGMP-VQYELLGQGSDNF 169
Query: 729 DIAIAEDGT---IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ ++ED + ++ PL +++ Y++T+ A N V + +V I++ + PP
Sbjct: 170 HLEVSEDDSTVGVYADAPLQVAEKEFYKLTLEAVVNDEV----AMTEVQIWVLGLH--PP 223
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
VF +++ I ENS +GT + + ATD D G N Y L + F V + +G+
Sbjct: 224 VFAFSSFIYSIAENSPVGT---IAGTVFATDEDMGENGRVTYHLL-KLNRYFTVGQESGL 279
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG 871
V + E Y + +VARD G
Sbjct: 280 VTVTEPTPVGE----YTMQVVARDAG 301
Score = 48.0 bits (109), Expect = 0.002
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 8/103 (7%)
Query: 245 SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ-LNNPLKTAQARVEIELLDLNDNL 303
S+D +G + L +++D + +++ L+VQA++ + + L T RV +E+ D+ND +
Sbjct: 591 SIDPSSGQIKLLEKVDREV-----LDSYFLEVQATEDVQDGLSTT-VRVNVEVTDINDCV 644
Query: 304 PEFEVDFYNI-SIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
P+FE + Y+ +++E + + V ATD D N TY L
Sbjct: 645 PKFERETYSFRNVIETIDTTTPIGTVAATDCDADPNNILTYSL 687
Score = 48.0 bits (109), Expect = 0.002
Identities = 51/174 (29%), Positives = 73/174 (41%), Gaps = 17/174 (9%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNIS----VRVFVKDVNDHFPVF 1045
F I+ G + + L ES ++L + A DGG +++ + V V D ND+ P F
Sbjct: 1428 FTIDAVTGQITLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDENDNSPFF 1487
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADF-GQNANLTYFI-----QPSDTDLPFEISPLT 1099
+ Y +V E + +V A D D Q +TY P+D F+I T
Sbjct: 1488 PELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSGLFQIDGST 1547
Query: 1100 GVLSV--NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
G ++V LDRE D Y L + A D DVNDN+P F
Sbjct: 1548 GWVTVKSGAVLDREKNDTYTLRIRASD---VPNSEALTDAIIQILDVNDNAPVF 1598
Score = 42.3 bits (95), Expect = 0.099
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 419 YVFPDKVGTKTENIEYYDEQ-LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT 477
Y P+K+ T T ++ S + + +LD ND P F P+ ++ + VGT
Sbjct: 1667 YESPNKLYTLTITVDDNSGPGSQSQTTITIDVLDVNDVAPTFNPAEYVSANVLESVDVGT 1726
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSN 504
IG V A DP+ G G + + S+
Sbjct: 1727 SIGTVSASDPEAGVFGQFTFSIDPASD 1753
Score = 41.9 bits (94), Expect = 0.13
Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 18/157 (11%)
Query: 1012 EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
++ L++ A D + V +F H P F + YN V T V+G+ + D
Sbjct: 512 KYILSVYAQDENGSSIPAEVNIFG---GSHPPQFTQEVYNVAV-----TEEVIGEQNVID 563
Query: 1072 AD-FG-QNANLTYFIQPSDTDLPF---EISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
D F N +T+ + S+T+ P I P +G + + ++DRE D Y L V A ++
Sbjct: 564 IDAFSFSNVAVTFALLNSETNQPIPRHSIDPSSGQIKLLEKVDREVLDSYFLEVQATED- 622
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKF----YAFDELLE 1159
D+ND PKF Y+F ++E
Sbjct: 623 VQDGLSTTVRVNVEVTDINDCVPKFERETYSFRNVIE 659
Score = 41.1 bits (92), Expect = 0.23
Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 19/228 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
E++ +GT+I ++A D ++G+ GQ + F+ + P L + E+ + R V
Sbjct: 1720 ESVDVGTSIGTVSASDPEAGVFGQ--FTFSIDPASDPDGLFS-IEEISPIGAV--RRADV 1774
Query: 1002 IVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
A+ L E+ L + A D G L ++ + + DVND P F T Y ++E
Sbjct: 1775 KTAKPLDRENVETHVLTLRATDLGVPPLTGYATLNLTLDDVNDTPPTF-ATDYRPTIKEN 1833
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQP-SDTD--LPFEISPLTG-VLSVNGE---LDR 1110
+ +G + A D D T ++P +DTD F++ TG LS++ + DR
Sbjct: 1834 LAEVQFVGYISAKDEDPTGGPPFTLVVEPNTDTDSFTWFDVGGTTGNNLSISSKAISFDR 1893
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
ET+ Y + + D D NDN P F E+L
Sbjct: 1894 ETQATYSIPIRITDR-APNGNSGVNYLIVEIEDENDN-PHFGTTKEML 1939
Score = 39.9 bits (89), Expect = 0.53
Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 11/119 (9%)
Query: 1010 ESEF-RLNISALDGGNLNDNISV-RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
E EF +L + A+ +ND +++ V + + H PVF + + +++ E + G V
Sbjct: 192 EKEFYKLTLEAV----VNDEVAMTEVQIWVLGLHPPVFAFSSFIYSIAENSPVGTIAGTV 247
Query: 1068 DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
ATD D G+N +TY + + F + +G+++V + +Y + VVARD G
Sbjct: 248 FATDEDMGENGRVTYHL--LKLNRYFTVGQESGLVTVT---EPTPVGEYTMQVVARDAG 301
Score = 37.9 bits (84), Expect = 2.1
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 1436 LTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAALARD 1482
L QATD+D G+NA+I Y I P F ID V+G + L R+
Sbjct: 867 LIKVQATDADKGVNAEIAYDIAGSNNP-FTIDAVTGDISTQDPLDRE 912
Score = 35.9 bits (79), Expect = 8.6
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 19/163 (11%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G+ +R+ L SG LF++D +G +++ L + + Q ++L V A N
Sbjct: 473 GSDVRFYLNSGGSG-LFTVDEESG--WIKTSLS-EGQGYQQGQKYILSVYAQDENG---- 524
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-- 345
+ E+ + + P+F + YN+++ E + +V+ + D N T+ L
Sbjct: 525 SSIPAEVNIFG-GSHPPQFTQEVYNVAVTEEVIGEQNVIDI---DAFSFSNVAVTFALLN 580
Query: 346 ---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ P SIDP SG + + + +DRE S ++V A E
Sbjct: 581 SETNQPIPRHSIDPSSGQIKLLEK--VDREVLDSYFLEVQATE 621
>UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=119;
Amniota|Rep: Protocadherin gamma A10 precursor - Homo
sapiens (Human)
Length = 936
Score = 100 bits (239), Expect = 4e-19
Identities = 115/471 (24%), Positives = 191/471 (40%), Gaps = 35/471 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + +E+ + D NDN P F NL + + N G +A+DPD+G N +
Sbjct: 115 EDRVKLFGIEIEVTDINDNAPKFQAENL-DVKINENVAAGMRFPLPEAIDPDVGVNSLQS 173
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + ++ + N V E + E H L + ASD +P L
Sbjct: 174 YQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDG-GDPLRSGTVLV 232
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
VT+ + P F Y V N+ +GT + + D E +V+Y
Sbjct: 233 SVTVFDAND------NAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFR 286
Query: 612 HGYE-EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
+ + + F + + +G I + ++L Y+ E A A L+ + V DVN
Sbjct: 287 KLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYLA-TAKVLITVEDVN 345
Query: 671 DERGVL-LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
D L + SP+ +++ G + + N+ + G V I +
Sbjct: 346 DNSPELTITSLFSPV---TEDSPLGTVVALL---NVHDLDSEQNGQVTCSILAYLPFKLE 399
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+I + + LDRE+ Y +TV A + G + + + D NDNPP F
Sbjct: 400 KSIDSYYRLVIHRALDREQVSSYNITVTAT-DGGSPPLSTEAHFMLQVADINDNPPTFSQ 458
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG------KEMFDVDENT 843
+Y +I EN+ G I + A D D NA +Y+L + ++ +T
Sbjct: 459 VSYFTYIPENNARGASIFS---VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDT 515
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
GV+ + S D E+ ++ + A D+G LSS L + + D+NDN PE
Sbjct: 516 GVL-YALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPE 565
Score = 81.4 bits (192), Expect = 2e-13
Identities = 48/130 (36%), Positives = 67/130 (51%), Gaps = 2/130 (1%)
Query: 214 FPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
FP P AID D+GV + Y+L L NG + E L+ + +A
Sbjct: 156 FPLP-EAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEEA-IHH 213
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L + AS +PL++ V + + D NDN P F + Y +S+ ENLP G +L V ATD+
Sbjct: 214 LVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDR 273
Query: 334 DQGENGEFTY 343
D+G NGE TY
Sbjct: 274 DEGANGEVTY 283
Score = 79.8 bits (188), Expect = 5e-13
Identities = 63/217 (29%), Positives = 95/217 (43%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN+P+GT ++ + A D D G NG++ Y F +P ++L F +N+ G
Sbjct: 255 VPENLPVGTQLLTVTATDRDEGANGEVTYSFRK---LPDTQLLK--------FQLNKYTG 303
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ ++ +L E + + I A DGG V + V+DVND+ P T V E
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPVTED 363
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV---LSVNGELDRETED 1114
V+ ++ D D QN +T I LPF++ L ++ LDRE
Sbjct: 364 SPLGTVVALLNVHDLDSEQNGQVTCSIL---AYLPFKLEKSIDSYYRLVIHRALDREQVS 420
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y +TV A D G D+NDN P F
Sbjct: 421 SYNITVTATDGG-SPPLSTEAHFMLQVADINDNPPTF 456
Score = 73.3 bits (172), Expect = 5e-11
Identities = 102/405 (25%), Positives = 167/405 (41%), Gaps = 43/405 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+ G A+D D G+N Y+ + P+K + ++ + V ++
Sbjct: 146 INENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGV---KYP 196
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ SL E E L ++A DGG+ + + V V V D ND+ PVF Y +V
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVP 256
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTD-LPFEISPLTGVLSVNGELDRETE 1113
E L V ATD D G N +TY F + DT L F+++ TG + ++ LD E
Sbjct: 257 ENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEET 316
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y + + A D G DVNDNSP+ + P ++
Sbjct: 317 GFYEIEIQAEDGG---AYLATAKVLITVEDVNDNSPEL----TITSLFSPVTEDSPLGTV 369
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FIGNGNGLILYSLPQRK--NQQNL--- 1227
V ++ V+ E+N + ++ + I + L+++ R+ + N+
Sbjct: 370 --VALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVT 427
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL-- 1281
G P LS+ A M+ VAD+ D + P F Y I EN + S+
Sbjct: 428 ATDGGSPPLSTEAHFMLQVADIND-----NPPTFSQVSYFTYIPENNARGASIFSVTALD 482
Query: 1282 TEHYENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
+ EN ++ Y + + + I+ G LY +RS D E
Sbjct: 483 PDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYE 527
Score = 65.3 bits (152), Expect = 1e-08
Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 15/195 (7%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I + LD E+ Y + + AE ++ A +V I +ED NDN P +
Sbjct: 303 GEIKISENLDYEETGFYEIEIQAEDGGAYLATA---KVLITVEDVNDNSPELTITSLFSP 359
Query: 796 IMENSKIGTEIKMDNIIKATDADEG--TNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
+ E+S +GT + + N+ G T ++ Y F K +D +V I +L
Sbjct: 360 VTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKS---IDSYYRLV--IHRAL 414
Query: 854 DREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLN 911
DRE+ Y +++ A D G LS+EA ++ + D NDN P F+Q+ + + E
Sbjct: 415 DREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYI---PENNAR 471
Query: 912 GTAGFTIIEVKPKNK 926
G + F++ + P +K
Sbjct: 472 GASIFSVTALDPDSK 486
Score = 62.5 bits (145), Expect = 9e-08
Identities = 66/226 (29%), Positives = 99/226 (43%), Gaps = 21/226 (9%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
T +++V N Q+ IPEN G +I + ALD DS N QI Y
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAE 497
Query: 973 EVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDN 1028
+ + + + Y IN G + RS E E ++ ++A D G+ L+ N
Sbjct: 498 D--------TIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSN 549
Query: 1029 ISVRVFVKDVNDHFPVF----KKTWYNFNVEEAQYTRR---VLGKVDATDADFGQNANLT 1081
+S+ +FV D ND+ P T + VE A + ++ KV A D D GQNA L+
Sbjct: 550 VSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLS 609
Query: 1082 YFIQPSDTDLPFEISPLTG-VLSVNGELDRETEDKYILTVVARDNG 1126
Y + + F + TG V + LDR+ K L V +D+G
Sbjct: 610 YRLLKASEPGLFAVGEHTGEVRTARALLDRDAL-KQSLVVAVQDHG 654
Score = 61.3 bits (142), Expect = 2e-07
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 9/164 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G++ T +DRE+ + FN V ++ + I + D NDN P F+ +
Sbjct: 86 GSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQAENLDVK 145
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGD 851
I EN G + +A D D G N+L Y L V VK+ +
Sbjct: 146 INENVAAGMRFPLP---EAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEH 202
Query: 852 SLDREKKIMYKLSLVARDTGG-LSSEAELI-IMIGDENDNKPEF 893
SLDRE++ ++ L L A D G L S L+ + + D NDN P F
Sbjct: 203 SLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVF 246
Score = 52.8 bits (121), Expect = 7e-05
Identities = 75/322 (23%), Positives = 130/322 (40%), Gaps = 40/322 (12%)
Query: 79 AYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLT--------- 129
A V + +EDVNDN P T V E +P G + + +
Sbjct: 333 ATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILA 392
Query: 130 -IPLTVPRGLTIFKDI---RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLR 185
+P + + + + + RA DR++ ++ N V + D G L + +L +
Sbjct: 393 YLPFKLEKSIDSYYRLVIHRALDREQVSSYNITV-----TATDGGSPPLSTEAHFMLQVA 447
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL----ISGNDR 241
+ D + +F + A+D D A + Y L I G
Sbjct: 448 DINDNPPTFSQVSYFTYIPENNARGASIFS--VTALDPDSKENAQIIYSLAEDTIQGVPL 505
Query: 242 KLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
+ S++S G L+ + D + H LQ +QV AS +P ++ + + +LD N
Sbjct: 506 SSYISINSDTGVLYALRSFDYEQFHELQ-----MQVTASDSGDPPLSSNVSLSLFVLDQN 560
Query: 301 DNLPEF---EVDFYNISIVENLPN----GFSVLQVMATDKDQGENGEFTYQL--DDPKGA 351
DN PE + + VE P G+ V +V+A D+D G+N +Y+L G
Sbjct: 561 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 620
Query: 352 FSIDPRSGWLTVRNQTVLDREA 373
F++ +G + + +LDR+A
Sbjct: 621 FAVGEHTGEVRTA-RALLDRDA 641
Score = 50.0 bits (114), Expect = 5e-04
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 9/126 (7%)
Query: 268 QANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
Q +++ + V A+ +P + +A +++ D+NDN P F Y I EN G S+
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQT-VL------DREAHSSLRMK 380
V A D D EN + Y L + P S ++++ + T VL D E L+M+
Sbjct: 478 VTALDPDSKENAQIIYSL--AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQ 535
Query: 381 VYAKET 386
V A ++
Sbjct: 536 VTASDS 541
Score = 49.2 bits (112), Expect = 9e-04
Identities = 43/142 (30%), Positives = 67/142 (47%), Gaps = 9/142 (6%)
Query: 221 IDQDLGVG----ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I +DLG+ A ++S +LFSL+ +GSL +D + L A + V
Sbjct: 52 ISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRIDRE---ELCAQSARCVV 108
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ L + +EIE+ D+NDN P+F+ + ++ I EN+ G A D D G
Sbjct: 109 SFNILVED-RVKLFGIEIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVG 167
Query: 337 ENGEFTYQLDDPKGAFSIDPRS 358
N +YQL P FS+ +S
Sbjct: 168 VNSLQSYQL-SPNKHFSLRVQS 188
Score = 47.6 bits (108), Expect = 0.003
Identities = 80/332 (24%), Positives = 133/332 (40%), Gaps = 57/332 (17%)
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F ++P +G L G +DRE V N D+NDN+PKF
Sbjct: 79 FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQ 138
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI----G 1208
A E L+ K N N + M P+ +A I+ + + + + + + F
Sbjct: 139 A--ENLDVK-------INENVAAGMRFPLPEA-IDPDVGVNSLQSYQLSPNKHFSLRVQS 188
Query: 1209 NGNG-----LIL-YSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDK 1254
NG L+L +SL + + + G P S T ++ VTV D D
Sbjct: 189 RANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNA----- 243
Query: 1255 PVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRN 1312
PVF Y + + EN+ +L+++ T+ E N ++ Y DT + + F ++
Sbjct: 244 PVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYT 302
Query: 1313 GTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
G + + + D E YE+ ++AE G KV++ ++D
Sbjct: 303 GEIKISENLDYEETGFYEIEIQAED-------------------GGAYLATAKVLITVED 343
Query: 1373 VNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
VNDNSP+ T + L + + +P G V L
Sbjct: 344 VNDNSPELTITS--LFSPVTEDSPLGTVVALL 373
Score = 46.8 bits (106), Expect = 0.005
Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 9/127 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL--FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+D G + Y D +L F L+ G + + + LD + + + ++
Sbjct: 268 VTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYE-----ETGFYEIE 322
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+QA L TA+ + +E D+NDN PE + + E+ P G V + D D
Sbjct: 323 IQAEDGGAYLATAKVLITVE--DVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDS 380
Query: 336 GENGEFT 342
+NG+ T
Sbjct: 381 EQNGQVT 387
Score = 41.1 bits (92), Expect = 0.23
Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 13/132 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNP-VFVP------SNLYEFSMKSNAKVGTVIGKVKAVDPD 488
D L S V++ + +LD NDN P + P S E + +S A+ G ++ KV AVD D
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRS-AEPGYLVTKVVAVDRD 601
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPS 546
GQN + Y L + S + F + +TG V A + + + +L V D P
Sbjct: 602 SGQNAWLSYRLLKASEPGL---FAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPL 658
Query: 547 ERRYSLAVVTIE 558
+L V +
Sbjct: 659 SATVTLTVAVAD 670
>UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor
(PCDH-alpha13).; n=6; Xenopus tropicalis|Rep:
Protocadherin alpha 13 precursor (PCDH-alpha13). -
Xenopus tropicalis
Length = 779
Score = 99 bits (238), Expect = 5e-19
Identities = 85/296 (28%), Positives = 136/296 (45%), Gaps = 25/296 (8%)
Query: 620 FAVEERSGVITVVDDLSRYN----RPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
F V +G + V D + R + P+ A+ EN L+I + + + D+ND
Sbjct: 85 FNVNLENGNLYVADRIDRESVCEMTPICSLSLEAVVENP-LNIF-HVEIEIKDINDNSPS 142
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTN--MSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + I + +G + M+S+ + N + +D I
Sbjct: 143 FSKDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISKNEYFKLNVKTSSDGRMIP 202
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E + ++PLDREK+ ++ ++ + G+ + GI + I I D NDN P+F Y+
Sbjct: 203 E---LVLERPLDREKQSALQI-ILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQ 258
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK---EMFDVDENTGVVKFIG 850
+ E++ + T + N ATDADEG N Y L K + F +D TG ++ G
Sbjct: 259 VSLTESAPVNTLVIQMN---ATDADEGVNGHITYYLSRISKAAQQKFTIDTETGEIRTKG 315
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF------NQIEENS 900
+LD E Y++ + A+D GGL S A+++I I D NDN PE N I ENS
Sbjct: 316 -TLDFETTKAYEMIVEAQDGGGLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENS 370
Score = 97.5 bits (232), Expect = 2e-18
Identities = 105/473 (22%), Positives = 191/473 (40%), Gaps = 27/473 (5%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNL-YEFSMKSNAKVGTVIGKVKAVDPDL 489
++E E ++ +VE+ + D NDN+P F + E + ++ ++G A+DPD
Sbjct: 115 SLEAVVENPLNIFHVEIEIKDINDNSPSFSKDTMNLEITELTHPGTRFILG--DALDPDD 172
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERR 549
G N + YD+ + + + V E P+ + + R
Sbjct: 173 GMNSLQAYDISKNEYFKLNVKTSSDGRMIPELVLERPLDREKQSALQIILTALDGGIPAR 232
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVS 607
++++ I ++ + P F Y+ + + + T V Q+ DA E ++
Sbjct: 233 TGISMIKIIIS----DINDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGVNGHIT 288
Query: 608 YDLLH-GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
Y L F ++ +G I L Y+ V Q+ L + +
Sbjct: 289 YYLSRISKAAQQKFTIDTETGEIRTKGTLDFETTKAYEM-IVEAQDGGGLFSNAKVVIQI 347
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
VD ND ++ + + + ENS + I N+ I GNV I +
Sbjct: 348 VDANDNAPEIIL---TSVSNSIPENSVPGTV--IALINIRDIDSGENGNVYCQITDLLPF 402
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
+ + + T + LDRE+ Y +T+ A ++G S + + + + D NDNPPV
Sbjct: 403 EITSSSSNYFRLLTTRNLDREEMHEYNITIKAT-DRGSPSLSTTKTIKLVLLDVNDNPPV 461
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVV 846
F A+Y +I EN+ G+ + ++A+D D NA Y++ + F V +
Sbjct: 462 FGQASYVVYIPENNPSGSSVFQ---VQASDPDLDDNAKITYSIMNTNTDNFPVSSYISIN 518
Query: 847 KFIG-----DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
G D E+ + + ++A+D G L+S + I I D NDN P+
Sbjct: 519 SMTGILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTTTVTICITDLNDNSPK 571
Score = 88.6 bits (210), Expect = 1e-15
Identities = 112/473 (23%), Positives = 206/473 (43%), Gaps = 35/473 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D NDN+P+F LY+ S+ +A V T++ ++ A D D G NG + Y L R S
Sbjct: 238 IKIIISDINDNSPLF-SQELYQVSLTESAPVNTLVIQMNATDADEGVNGHITYYLSRISK 296
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I+ TG + + E A + VEA D +S A V I++
Sbjct: 297 -AAQQKFTIDTETGEIRTKGTLDFETTKAYEMIVEAQD-----GGGLFSNAKVVIQIV-D 349
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I + + N GT + I + D + + ++ + +PF +
Sbjct: 350 ANDNAPEI---ILTSVSNSIPENSVPGTVIALINIRDI--DSGENGNVYCQITDLLPFEI 404
Query: 623 -EERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVV--DVNDERGVLLK 678
S ++ + M+++ + + + S+ T T+ +V DVND V
Sbjct: 405 TSSSSNYFRLLTTRNLDREEMHEYNITIKATDRGSPSLSTTKTIKLVLLDVNDNPPVF-- 462
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD--VTDDIAI-AED 735
G S +++ + N +G+++ Q+ + + N + N + V+ I+I +
Sbjct: 463 GQASYVVYIPENNPSGSSVFQV-QASDPDLDDNAKITYSIMNTNTDNFPVSSYISINSMT 521
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G ++ Q+P D E+ + + V+A+ N G VTI I D NDN P + +
Sbjct: 522 GILYAQRPFDYEQLREFGIQVMAKDN-GSPPLNSTTTVTICITDLNDNSPKILYPSTSAD 580
Query: 796 IMENSKI--GTEIKMDNIIK--ATDADEGTNALFMYTLFGEGKEM-FDVDENTGVVKFIG 850
+I T K + + K A DAD G NA Y + M F + +TG ++ +
Sbjct: 581 DSAQFEIVPRTSNKGELVAKVVAVDADSGHNAWLSYEFLQVSESMSFTISRHTGEIRTLR 640
Query: 851 DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDE-NDNKPEFNQIEENS 900
++E + +L ++ +D G S+ L +++ D + P+ N +NS
Sbjct: 641 VFPEKE-TLKQRLVVLVKDNGSPPRSATINLNLVVADNFQQDIPQMNNQLQNS 692
Score = 83.8 bits (198), Expect = 3e-14
Identities = 107/408 (26%), Positives = 176/408 (43%), Gaps = 39/408 (9%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS-KLSADALEVKRYFVINERHGHVIVAR 1005
GT I +ALD D G+N Y+ + Y + K S+D + +++ R
Sbjct: 159 GTRFILGDALDPDDGMNSLQAYDISKNEYFKLNVKTSSDGRMIPE----------LVLER 208
Query: 1006 SLPPESEFRLNI--SALDGG-NLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
L E + L I +ALDGG IS +++ + D+ND+ P+F + Y ++ E+
Sbjct: 209 PLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLTESAPVN 268
Query: 1062 RVLGKVDATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETEDKYILT 1119
++ +++ATDAD G N ++TY++ F I TG + G LD ET Y +
Sbjct: 269 TLVIQMNATDADEGVNGHITYYLSRISKAAQQKFTIDTETGEIRTKGTLDFETTKAYEMI 328
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY---AFDELLEWKHP-EADELSN-HNFE 1174
V A+D G D NDN+P+ + + E P L N + +
Sbjct: 329 VEAQDGG---GLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRDID 385
Query: 1175 SVMMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSL 1232
S VY I + P I ++ + F T + + Y++ + + G PSL
Sbjct: 386 SGENGNVY-CQITDLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITIKATDR--GSPSL 442
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHYENFKM 1290
S+T + + + DV D + PVF Y + I EN + V V + + +N K+
Sbjct: 443 STTKTIKLVLLDVND-----NPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAKI 497
Query: 1291 RYYILNENDTD--IRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
Y I+N N + + I+ G LY R D E + + V A+
Sbjct: 498 TYSIMNTNTDNFPVSSYISINSMTGILYAQRPFDYEQLREFGIQVMAK 545
Score = 83.0 bits (196), Expect = 6e-14
Identities = 68/242 (28%), Positives = 114/242 (47%), Gaps = 23/242 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
+I++ N A ++ IPEN GT I +N D+DSG NG + + +
Sbjct: 344 VIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRDIDSGENGNVYCQITD---LL 400
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRV 1033
P ++++ + YF ++ R+L E E+ + I A D G+ L+ ++++
Sbjct: 401 PFEITSSS---SNYF-------RLLTTRNLDREEMHEYNITIKATDRGSPSLSTTKTIKL 450
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD-LP 1092
+ DVND+ PVF + Y + E + + +V A+D D NA +TY I ++TD P
Sbjct: 451 VLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAKITYSIMNTNTDNFP 510
Query: 1093 ----FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
I+ +TG+L D E ++ + V+A+DNG D+NDNS
Sbjct: 511 VSSYISINSMTGILYAQRPFDYEQLREFGIQVMAKDNG-SPPLNSTTTVTICITDLNDNS 569
Query: 1149 PK 1150
PK
Sbjct: 570 PK 571
Score = 82.6 bits (195), Expect = 8e-14
Identities = 65/217 (29%), Positives = 102/217 (47%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P+ T +I++NA D D G+NG I Y Y+ S++S A ++ F I+ G
Sbjct: 261 LTESAPVNTLVIQMNATDADEGVNGHITY------YL--SRISKAA---QQKFTIDTETG 309
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ +L E+ + + + A DGG L N V + + D ND+ P T + ++ E
Sbjct: 310 EIRTKGTLDFETTKAYEMIVEAQDGGGLFSNAKVVIQIVDANDNAPEIILTSVSNSIPEN 369
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
V+ ++ D D G+N N+ + Q +D LPFEI+ + L LDRE
Sbjct: 370 SVPGTVIALINIRDIDSGENGNV--YCQITDL-LPFEITSSSSNYFRLLTTRNLDREEMH 426
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +T+ A D G DVNDN P F
Sbjct: 427 EYNITIKATDRG-SPSLSTTKTIKLVLLDVNDNPPVF 462
Score = 73.3 bits (172), Expect = 5e-11
Identities = 52/172 (30%), Positives = 85/172 (49%), Gaps = 11/172 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G+ + Y++ KL S +G + E L+ + Q+ LQ+ +
Sbjct: 167 ALDPDDGMNSLQAYDISKNEYFKLNVKTSSDGRMIPELVLERPLDREKQS---ALQIILT 223
Query: 280 QLNN--PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
L+ P +T + ++I + D+NDN P F + Y +S+ E+ P V+Q+ ATD D+G
Sbjct: 224 ALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGV 283
Query: 338 NGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG TY L A F+ID +G +R + LD E + M V A++
Sbjct: 284 NGHITYYLSRISKAAQQKFTIDTETG--EIRTKGTLDFETTKAYEMIVEAQD 333
Score = 64.5 bits (150), Expect = 2e-08
Identities = 59/199 (29%), Positives = 92/199 (46%), Gaps = 21/199 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN P G+++ ++ A D D N +I Y + + D V Y IN G
Sbjct: 471 IPENNPSGSSVFQVQASDPDLDDNAKITYSIMNT--------NTDNFPVSSYISINSMTG 522
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFP--VFKKTWYNFN 1053
+ R E EF + + A D G+ LN +V + + D+ND+ P ++ T + +
Sbjct: 523 ILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTTTVTICITDLNDNSPKILYPSTSADDS 582
Query: 1054 VEEAQYTR-----RVLGKVDATDADFGQNANLTY-FIQPSDTDLPFEISPLTGVLSVNGE 1107
+ R ++ KV A DAD G NA L+Y F+Q S++ + F IS TG +
Sbjct: 583 AQFEIVPRTSNKGELVAKVVAVDADSGHNAWLSYEFLQVSES-MSFTISRHTGEIRTLRV 641
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ K L V+ +DNG
Sbjct: 642 FPEKETLKQRLVVLVKDNG 660
Score = 59.3 bits (137), Expect = 8e-07
Identities = 68/294 (23%), Positives = 121/294 (41%), Gaps = 29/294 (9%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L + G+ + + + I D+NDN P+F Y V++ E P
Sbjct: 222 LTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADE 281
Query: 127 SLTIPLT---------VPRGLTIFKDIRAF-DRDKPNTPNSDVHYSIVSGNDDGHFALES 176
+ +T + TI + + + + + IV D G L S
Sbjct: 282 GVNGHITYYLSRISKAAQQKFTIDTETGEIRTKGTLDFETTKAYEMIVEAQDGG--GLFS 339
Query: 177 SHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLR 232
+ K V+ + DA D ++++ + I + + P + A+ D D G +
Sbjct: 340 NAKVVIQI-----VDANDNAPEIILTSVSNSIPENSV-PGTVIALINIRDIDSGENGNVY 393
Query: 233 YELISGNDRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
++ D F + S + + F L +LD E + N + ++A+ +P +
Sbjct: 394 CQI---TDLLPFEITSSSSNYFRLLTTRNLDREEMHEYN---ITIKATDRGSPSLSTTKT 447
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+++ LLD+NDN P F Y + I EN P+G SV QV A+D D +N + TY +
Sbjct: 448 IKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAKITYSI 501
Score = 53.2 bits (122), Expect = 5e-05
Identities = 50/183 (27%), Positives = 80/183 (43%), Gaps = 14/183 (7%)
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESEFRLN-ISALDGGNLNDN----ISVRVF 1034
K ++ + +F +N +G++ VA + ES + I +L + +N V +
Sbjct: 73 KFRISSVTAEHFFNVNLENGNLYVADRIDRESVCEMTPICSLSLEAVVENPLNIFHVEIE 132
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQY--TRRVLGKVDATDADFGQNANLTYFIQPSD-TDL 1091
+KD+ND+ P F K N + E + TR +LG DA D D G N+ Y I ++ L
Sbjct: 133 IKDINDNSPSFSKDTMNLEITELTHPGTRFILG--DALDPDDGMNSLQAYDISKNEYFKL 190
Query: 1092 PFEISP---LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
+ S + L + LDRE + + + A D G D+NDNS
Sbjct: 191 NVKTSSDGRMIPELVLERPLDREKQSALQIILTALDGG-IPARTGISMIKIIISDINDNS 249
Query: 1149 PKF 1151
P F
Sbjct: 250 PLF 252
Score = 52.0 bits (119), Expect = 1e-04
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 10/179 (5%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
++A D D GV + Y L IS ++ F++D+ G + + LD + +A +++
Sbjct: 274 MNATDADEGVNGHITYYLSRISKAAQQKFTIDTETGEIRTKGTLDFETT---KAYEMIVE 330
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
Q + + A+V I+++D NDN PE + + SI EN G + + D D
Sbjct: 331 AQ----DGGGLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRDIDS 386
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
GENG Q+ D S + + LDRE + + A + +PS+ T
Sbjct: 387 GENGNVYCQITDLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITIKATDRGSPSLSTT 445
Score = 47.2 bits (107), Expect = 0.003
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 8/129 (6%)
Query: 221 IDQDLGVG----ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I +DLG+ A ++ + S F+++ NG+L++ +D ++ + L +
Sbjct: 58 IAKDLGLSIQDLAKRKFRISSVTAEHFFNVNLENGNLYVADRIDRESVCEMTP-ICSLSL 116
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+A + NPL VEIE+ D+NDN P F D N+ I E G + A D D G
Sbjct: 117 EAV-VENPLNIFH--VEIEIKDINDNSPSFSKDTMNLEITELTHPGTRFILGDALDPDDG 173
Query: 337 ENGEFTYQL 345
N Y +
Sbjct: 174 MNSLQAYDI 182
Score = 46.8 bits (106), Expect = 0.005
Identities = 67/282 (23%), Positives = 109/282 (38%), Gaps = 27/282 (9%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP----SLTIPLTVPRGL 138
V + I D NDN P + T ++ E + G + I I ++ +T
Sbjct: 343 VVIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRDIDSGENGNVYCQITDLLPF 402
Query: 139 TIFKDIRAFDR--DKPNTPNSDVH-YSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGD 194
I + R N ++H Y+I + D G +L ++ L+L V D
Sbjct: 403 EITSSSSNYFRLLTTRNLDREEMHEYNITIKATDRGSPSLSTTKTIKLVLLDVNDNPPVF 462
Query: 195 KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL-----FSLDSV 249
+ V+ +F + A D DL A + Y +++ N S++S+
Sbjct: 463 GQASYVVYIPENNPSGSSVFQ--VQASDPDLDDNAKITYSIMNTNTDNFPVSSYISINSM 520
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF--- 306
G L+ ++ D + Q F +QV A +P + V I + DLNDN P+
Sbjct: 521 TGILYAQRPFDYE-----QLREFGIQVMAKDNGSPPLNSTTTVTICITDLNDNSPKILYP 575
Query: 307 ---EVDFYNISIVENLPN-GFSVLQVMATDKDQGENGEFTYQ 344
D IV N G V +V+A D D G N +Y+
Sbjct: 576 STSADDSAQFEIVPRTSNKGELVAKVVAVDADSGHNAWLSYE 617
>UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17;
Theria|Rep: Protocadherin LKC precursor - Homo sapiens
(Human)
Length = 1310
Score = 99 bits (238), Expect = 5e-19
Identities = 142/487 (29%), Positives = 217/487 (44%), Gaps = 56/487 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D NDN PVF + + S+ VG+V+ V AVD D+G GMV+Y +++ T
Sbjct: 112 VIVEDRNDNAPVF-QNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPST 170
Query: 507 ITSP--FKINPNTGTVSVAESPILEGRHALF---VEASDQPA---NPSERRYSLAV-VTI 557
S F+I N G++ + S + A + ++A D N + SL V ++I
Sbjct: 171 GDSEHLFRILAN-GSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSI 229
Query: 558 EVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-ND-VSYDLLHGY 614
V ++PD+ P F+ Y V + GTSV + D + ND V Y + +
Sbjct: 230 SVV-----DQPDLDPQFVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYST 284
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA---NLSIVTN-------ATV 664
G F + GVI V L R D E V LQ A +L+I TV
Sbjct: 285 RPGW-FDI-GADGVIRVNGSLDREQLLEAD-EEVQLQVTATETHLNIYGQEAKVSIWVTV 341
Query: 665 HVVDVNDERGVLLKGAHSPIIFHVKE---NSAG----AAIGQIFHTNMSS-IYGNGTG-N 715
V+DVND + + F +E N G A +I +++ +Y G N
Sbjct: 342 RVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSN 401
Query: 716 VRFLIANQQDVTDDIAIAED---GTIFTQ------KPLDREKRDVYRMTVIAEFNKGVIS 766
FL++ + +++ + G+ Q +D E++ + V+A V
Sbjct: 402 GTFLLSLGGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVA--TDSVSQ 459
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+ VTI++ D ND+ P F + Y + E+S G+ + + I ATD D G
Sbjct: 460 NFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVV--TDSIHATDPDTGAWGQIT 517
Query: 827 YTLF-GEGKEMFDVDENTGVVKF-IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIG 884
Y+L G G ++F VD +G V G+ LDRE + +Y L+L A D G LSS L I +
Sbjct: 518 YSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGGNLSSSTTLQIHLL 577
Query: 885 DENDNKP 891
D NDN P
Sbjct: 578 DINDNAP 584
Score = 92.7 bits (220), Expect = 7e-17
Identities = 101/392 (25%), Positives = 173/392 (44%), Gaps = 49/392 (12%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FG 831
++I + D+ D P F Y + E++ GT + ++A D D+G N +Y++ +
Sbjct: 227 LSISVVDQPDLDPQFVREFYSASVAEDAAKGTSVLT---VEAVDGDKGINDPVIYSISYS 283
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIM----YKLSLVARDT--GGLSSEAELIIMIG- 884
FD+ + GV++ G SLDRE+ + +L + A +T EA++ I +
Sbjct: 284 TRPGWFDIGAD-GVIRVNG-SLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTV 341
Query: 885 ---DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
D ND+KPEF + E ++N T G+ P+ + +D L + P
Sbjct: 342 RVMDVNDHKPEFYNCSLPACTFTPEEAQVNFT-GYVDEHASPR----IPIDDLTMVVYDP 396
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
+ GT ++ L D ++ F+ S L V ER
Sbjct: 397 DKGSNGTFLLSLGGPDAEA---------FSVSPERAAGSASVQVLVRVSALVDYER---- 443
Query: 1002 IVARSLPPESEFRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
++ + + A D + N +++ V + ++D+NDH P F ++ Y V E T
Sbjct: 444 --------QTAMAVQVVATDSVSQNFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSAT 495
Query: 1061 RRVL-GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV-NGE-LDRETEDKYI 1117
V+ + ATD D G +TY + P + F++ P++G ++V NGE LDRE++ Y
Sbjct: 496 GSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYY 555
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
LT+ A D G D+NDN+P
Sbjct: 556 LTLQATDGG---NLSSSTTLQIHLLDINDNAP 584
Score = 85.0 bits (201), Expect = 1e-14
Identities = 179/756 (23%), Positives = 303/756 (40%), Gaps = 109/756 (14%)
Query: 427 TKTE-NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV-KA 484
T TE ++ Y ++ + V V ++D ND+ P F +L + G V +
Sbjct: 320 TATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEH 379
Query: 485 VDP--DLGQNGMVLYDLQRTSN----LTITSP----FKINPN--TGTVS----VAESPIL 528
P + MV+YD + SN L++ P F ++P G+ S V S ++
Sbjct: 380 ASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQVLVRVSALV 439
Query: 529 EGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGI 588
+ + + + +S+A+VTI + R ++P P + Y V +
Sbjct: 440 DYERQTAMAVQVVATDSVSQNFSVAMVTIHL-RDINDHRPTFPQSL---YVLTVPEHSAT 495
Query: 589 GTSV-GQIRVN--DAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDD--LSRYNRPMY 643
G+ V I D ++Y LL G + F V+ SG +TV + L R ++ +Y
Sbjct: 496 GSVVTDSIHATDPDTGAWGQITYSLLPGNGADL-FQVDPVSGTVTVRNGELLDRESQAVY 554
Query: 644 DFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT 703
+ + + NLS T +H++D+ND V + G+++ IF V+E ++ H
Sbjct: 555 -YLTLQATDGGNLSSSTTLQIHLLDINDNAPV-VSGSYN--IF-VQEEEGNVSVTIQAHD 609
Query: 704 NMSSIYGNGTGNVRFLI-ANQQDVTDDIAIAED-GTIFTQKPLDREKRDV-----YRMTV 756
N GT N R L + + ++ D G + PLDRE D +TV
Sbjct: 610 NDEP----GTNNSRLLFNLLPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTV 665
Query: 757 IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATD 816
+ + G + VTI +ED NDN P+F ++Y F ++ G + ++KA D
Sbjct: 666 LVSDCGEPVLGTKV-NVTITVEDINDNLPIFNQSSY-NFTVKEEDPGVLV---GVVKAWD 720
Query: 817 ADE-GTNALFMYTLFGEGKEMFDV-------DENTGVVKFIGD-SLDREKKIMYKLSLVA 867
AD+ N ++L G G F + G ++ D SLD E + ++ L++ A
Sbjct: 721 ADQTEANNRISFSLSGSGANYFMIRGLVLGAGWAEGYLRLPPDVSLDYETQPVFNLTVSA 780
Query: 868 R--DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
D G + ++ + + D NDN P + + +R+ +G +
Sbjct: 781 ENPDPQGGETIVDVCVNVKDVNDNPPTLD-VASLRGIRVAENGSQHGQVAVVV------- 832
Query: 926 KFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA 985
A DVD L I + + +D+ S G N VYI SK A
Sbjct: 833 --ASDVDTSAQL-----EIQLVNILCTKAGVDVGSLCWGWFSVAANGSVYINQSK----A 881
Query: 986 LEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVF 1045
++ + ++ V+ A L + F+ ++N S+ + ++DVND+ P F
Sbjct: 882 IDYEACDLVT----LVVRACDLATDPGFQA---------YSNNGSLLITIEDVNDNAPYF 928
Query: 1046 KKTWYNF-NVEEAQYTRRVLGKVDATDADFGQNANLTY------FIQPSDTDLPF----- 1093
F + E R + V A D D G N + + FI +PF
Sbjct: 929 LPENKTFVIIPELVLPNREVASVRARDDDSGNNGVILFSILRVDFISKDGATIPFQGVFS 988
Query: 1094 -----EISPLTGVLSVNGELDRETEDKYILTVVARD 1124
E G + LD + Y +TV ARD
Sbjct: 989 IFTSSEADVFAGSIQPVTSLDSTLQGTYQVTVQARD 1024
Score = 73.3 bits (172), Expect = 5e-11
Identities = 61/219 (27%), Positives = 101/219 (46%), Gaps = 19/219 (8%)
Query: 940 IPENIPIGTTII-KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYF-VINER 997
+PE+ G+ + ++A D D+G GQI Y +P + AD +V + R
Sbjct: 489 VPEHSATGSVVTDSIHATDPDTGAWGQITYSL-----LPGN--GADLFQVDPVSGTVTVR 541
Query: 998 HGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+G ++ S ++ + L + A DGGNL+ + ++++ + D+ND+ PV + YN V+E
Sbjct: 542 NGELLDRES---QAVYYLTLQATDGGNLSSSTTLQIHLLDINDNAPVVSGS-YNIFVQEE 597
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET----- 1112
+ V + D N+ L + + P F + P TG+L G LDRE
Sbjct: 598 EGNVSVTIQAHDNDEPGTNNSRLLFNLLPGPYSHNFSLDPDTGLLRNLGPLDREAIDPAL 657
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E + +LTV+ D G D+NDN P F
Sbjct: 658 EGRIVLTVLVSDCG-EPVLGTKVNVTITVEDINDNLPIF 695
Score = 68.9 bits (161), Expect = 1e-09
Identities = 55/160 (34%), Positives = 77/160 (48%), Gaps = 10/160 (6%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ IHA D D G + Y L+ GN LF +D V+G++ + LD E QA + L
Sbjct: 501 DSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRES--QA-VYYLT 557
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+QA+ N ++ ++I LLD+NDN P YNI + E N +Q D+
Sbjct: 558 LQATDGGN--LSSSTTLQIHLLDINDNAPVVS-GSYNIFVQEEEGNVSVTIQAHDNDEPG 614
Query: 336 GENGEFTYQ-LDDP-KGAFSIDPRSGWLTVRNQTVLDREA 373
N + L P FS+DP +G L RN LDREA
Sbjct: 615 TNNSRLLFNLLPGPYSHNFSLDPDTGLL--RNLGPLDREA 652
Score = 66.5 bits (155), Expect = 5e-09
Identities = 54/170 (31%), Positives = 83/170 (48%), Gaps = 8/170 (4%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSL--DSVNGSLFLEKELDLDAEHNLQANT-FVLQVQA 278
D D G T L G D + FS+ + GS ++ + + A + + T +QV A
Sbjct: 395 DPDKGSNGTFLLSL-GGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVA 453
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ-VMATDKDQGE 337
+ + + A V I L D+ND+ P F Y +++ E+ G V + ATD D G
Sbjct: 454 TDSVSQ-NFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGA 512
Query: 338 NGEFTYQLDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+ TY L GA F +DP SG +TVRN +LDRE+ + + + A +
Sbjct: 513 WGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATD 562
Score = 57.6 bits (133), Expect = 2e-06
Identities = 79/334 (23%), Positives = 128/334 (38%), Gaps = 26/334 (7%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPS-----LTIPLTVPRG 137
VT+++ D+ND+ P F + Y +TV E + TG + A + +T L G
Sbjct: 466 VTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNG 525
Query: 138 LTIFK------DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYD 191
+F+ + + + + + V+Y + D G+ + S+ + LL +
Sbjct: 526 ADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGGNLS-SSTTLQIHLLDINDNAP 584
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG 251
+ + + + I H D+ + L + L+ G FSLD G
Sbjct: 585 VVSGSYNIFVQEEEGNVSVTI----QAHDNDEPGTNNSRLLFNLLPGPYSHNFSLDPDTG 640
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
L LD +A VL V S P+ + V I + D+NDNLP F Y
Sbjct: 641 LLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSY 700
Query: 312 NISIVENLPNGFSVLQVMATDKDQGE-NGEFTYQLDDPKGAF----SIDPRSGW----LT 362
N ++ E P G V V A D DQ E N ++ L + + +GW L
Sbjct: 701 NFTVKEEDP-GVLVGVVKAWDADQTEANNRISFSLSGSGANYFMIRGLVLGAGWAEGYLR 759
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTFAD 396
+ LD E + V A+ +P T D
Sbjct: 760 LPPDVSLDYETQPVFNLTVSAENPDPQGGETIVD 793
Score = 56.0 bits (129), Expect = 7e-06
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 29/232 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E +P+G+ + + A+D D G G + Y E IP + D+ + R +G
Sbjct: 133 INETLPVGSVVFSVLAVDKDMGSAGMVVYSI--EKVIPS---TGDSEHLFRILA----NG 183
Query: 1000 HVIVARSLPPESE---FRLNISALDGGNLNDN-----ISVRVF----VKDVNDHFPVFKK 1047
+++ SL ++ ++L + A D G + N S+ VF V D D P F +
Sbjct: 184 SIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVR 243
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
+Y+ +V E + V+A D D G N + Y I S F+I GV+ VNG
Sbjct: 244 EFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIG-ADGVIRVNGS 302
Query: 1108 LDR----ETEDKYILTVVARD---NGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
LDR E +++ L V A + N DVND+ P+FY
Sbjct: 303 LDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFY 354
Score = 50.8 bits (116), Expect = 3e-04
Identities = 54/195 (27%), Positives = 88/195 (45%), Gaps = 34/195 (17%)
Query: 220 AIDQDLGVGATLRYEL-----ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
A+D+D+G + Y + +G+ LF + NGS+ L L +N ++ + L
Sbjct: 148 AVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRI-LANGSIVLNGSLS----YNNKSAFYQL 202
Query: 275 QVQASQLNNPLK---TAQARV----EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+++A L T Q + I ++D D P+F +FY+ S+ E+ G SVL
Sbjct: 203 ELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKGTSVLT 262
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL------TVRNQTVLDR----EAHSSL 377
V A D D+G N Y + S R GW +R LDR EA +
Sbjct: 263 VEAVDGDKGINDPVIYSI-------SYSTRPGWFDIGADGVIRVNGSLDREQLLEADEEV 315
Query: 378 RMKVYAKETNPSVVG 392
+++V A ET+ ++ G
Sbjct: 316 QLQVTATETHLNIYG 330
Score = 49.2 bits (112), Expect = 9e-04
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 221 IDQDLGVGATLRYELISG--NDRKLFSLDSVNGSLFL--EKELDLDAEHNLQANTFVLQV 276
+ +DL VGA + + ND + + S N F K ++ L T
Sbjct: 35 LPEDLPVGAQAFWLVAEDQDNDPLTYGMSSPNAYFFAVTPKTGEVKLASALDYETLYTFK 94
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+++P Q + + + D NDN P F+ ++ SI E LP G V V+A DKD G
Sbjct: 95 VTISVSDPYIQVQREMLVIVEDRNDNAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMG 154
Query: 337 ENGEFTYQLD 346
G Y ++
Sbjct: 155 SAGMVVYSIE 164
Score = 48.8 bits (111), Expect = 0.001
Identities = 85/364 (23%), Positives = 146/364 (40%), Gaps = 65/364 (17%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA--PIGPSLTIPLTV 134
I + V +ED NDN P+F +T + +++E P G F L +G + + ++
Sbjct: 104 IQVQREMLVIVEDRNDNAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSI 163
Query: 135 PRGLTIFKDIRAFDRDKPNTP----------NSDVHYSI------VSGNDDGHFALESSH 178
+ + D R N N Y + + G F ++ S
Sbjct: 164 EKVIPSTGDSEHLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCS- 222
Query: 179 KPVLLLRKVLDYDAGD----KEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYE 234
PV L V+D D +EF +A +L + A+D D G+ + Y
Sbjct: 223 LPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKGTSVL---TVEAVDGDKGINDPVIYS 279
Query: 235 LISGNDRKLFSLDS-----VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+ F + + VNGS L++E L+A+ +Q LQV A++ + + +
Sbjct: 280 ISYSTRPGWFDIGADGVIRVNGS--LDREQLLEADEEVQ-----LQVTATETHLNIYGQE 332
Query: 290 ARVEI----ELLDLNDNLPEF---------------EVDFYNISIVENLPN-GFSVLQVM 329
A+V I ++D+ND+ PEF +V+F P L ++
Sbjct: 333 AKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPIDDLTMV 392
Query: 330 ATDKDQGENGEFTYQLDDPKG-AFSIDPR------SGWLTVRNQTVLDREAHSSLRMKVY 382
D D+G NG F L P AFS+ P S + VR ++D E +++ ++V
Sbjct: 393 VYDPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVV 452
Query: 383 AKET 386
A ++
Sbjct: 453 ATDS 456
Score = 46.4 bits (105), Expect = 0.006
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 10/108 (9%)
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-- 829
++ + +ED NDN PVF++ + I E +G+ + + A D D G+ + +Y++
Sbjct: 109 EMLVIVEDRNDNAPVFQNTAFSTSINETLPVGSVVFS---VLAVDKDMGSAGMVVYSIEK 165
Query: 830 ----FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL 873
G+ + +F + N G + G K Y+L L A D GG+
Sbjct: 166 VIPSTGDSEHLFRILAN-GSIVLNGSLSYNNKSAFYQLELKACDLGGM 212
Score = 45.6 bits (103), Expect = 0.011
Identities = 47/158 (29%), Positives = 76/158 (48%), Gaps = 17/158 (10%)
Query: 1006 SLPPESEFRLNISAL--DGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTR 1061
++ P E R+ ++ L D G L ++V + V+D+ND+ P+F ++ YNF V+E +
Sbjct: 652 AIDPALEGRIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNFTVKE-EDPG 710
Query: 1062 RVLGKVDATDADFGQ-NANLTYFIQPSDTDLPFEISPLT-------GVLSV--NGELDRE 1111
++G V A DAD + N +++ + S + F I L G L + + LD E
Sbjct: 711 VLVGVVKAWDADQTEANNRISFSLSGSGANY-FMIRGLVLGAGWAEGYLRLPPDVSLDYE 769
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
T+ + LTV A +N DVNDN P
Sbjct: 770 TQPVFNLTVSA-ENPDPQGGETIVDVCVNVKDVNDNPP 806
Score = 44.8 bits (101), Expect = 0.018
Identities = 54/196 (27%), Positives = 88/196 (44%), Gaps = 27/196 (13%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++PE++P+G L A D D N + Y +S P+ +F + +
Sbjct: 34 ILPEDLPVGAQAFWLVAEDQD---NDPLTYGMSS-----PNAY---------FFAVTPKT 76
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G V +A +L E+ F++ IS D + + V V+D ND+ PVF+ T ++ ++ E
Sbjct: 77 GEVKLASALDYETLYTFKVTISVSDP-YIQVQREMLVIVEDRNDNAPVFQNTAFSTSINE 135
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQ---PS--DTDLPFEISPLTGVLSVNGELDRE 1111
V+ V A D D G + Y I+ PS D++ F I G + +NG L
Sbjct: 136 TLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRIL-ANGSIVLNGSLSYN 194
Query: 1112 TEDK-YILTVVARDNG 1126
+ Y L + A D G
Sbjct: 195 NKSAFYQLELKACDLG 210
Score = 38.3 bits (85), Expect = 1.6
Identities = 15/31 (48%), Positives = 23/31 (74%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDELTP 111
++VT+ +ED+NDN+PIF + Y+ TV E P
Sbjct: 679 VNVTITVEDINDNLPIFNQSSYNFTVKEEDP 709
>UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49;
Tetrapoda|Rep: Protocadherin gamma C5 precursor - Homo
sapiens (Human)
Length = 944
Score = 99.5 bits (237), Expect = 6e-19
Identities = 119/478 (24%), Positives = 193/478 (40%), Gaps = 39/478 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
++ E + + VEV +LD NDN+P F E + +A G A DPD+G
Sbjct: 106 VQVVTEHPLELIRVEVEILDLNDNSPSFATPER-EMRISESAASGARFPLDSAQDPDVGT 164
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSER 548
N + Y L S+ ++ + V E + + RH L + A D
Sbjct: 165 NTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSG 224
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
++V+ +++ + P F + + N IGT + ++ D E +
Sbjct: 225 TTLISVIVLDIN-------DNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQL 277
Query: 609 DLLHG--YEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNAT 663
D G E V F ++ SG I V+ + Y+ A A Q +
Sbjct: 278 DYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQ 337
Query: 664 VHVVDVNDERG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V V DVND VLL +P++ + G +G +F N+ G V I+
Sbjct: 338 VDVGDVNDNAPEVLLASLANPVL---ESTPVGTVVG-LF--NVRDRDSGRNGEVSLDIS- 390
Query: 723 QQDVTDDIAIAEDG-TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
D+ I +E+ ++ T +PLDRE Y + ++A + G S + + I D N
Sbjct: 391 -PDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLAS-DAGSPSLHKHLTIRLNISDVN 448
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------GKE 835
DN P F Y +I+EN G+ + + A+D D G NA Y++ G
Sbjct: 449 DNAPRFNQQLYTAYILENRPPGSLL---CTVAASDPDTGDNARLTYSIVGNQVQGAPASS 505
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
V+ G + F + D E M ++ + RD+G L + L + + DENDN P
Sbjct: 506 FVYVNPEDGRI-FAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAP 562
Score = 86.6 bits (205), Expect = 5e-15
Identities = 110/463 (23%), Positives = 203/463 (43%), Gaps = 40/463 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LD NDN P F S++ + NA +GT++ ++ A DPD G NG + Y ++
Sbjct: 228 ISVIVLDINDNAPTF-QSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTS 286
Query: 505 LTITSPFKINPNTGTVSVAESPI--LEGR-HALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ + F ++P++G + V PI E R + + A DQ P+ + V+ ++V
Sbjct: 287 EAVRNLFGLDPSSGAIHVL-GPIDFEESRFYEIHARARDQ-GQPAMEGH--CVIQVDVG- 341
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG--QIRVNDAFEQNDVSYDLLHGYEEGVP 619
N P++ + A V + +GT VG +R D+ +VS D+ +P
Sbjct: 342 DVNDNAPEV---LLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDI----SPDLP 394
Query: 620 FAVE--ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATV--HVVDVNDERGV 675
F ++ E + L R Y E +A + + S+ + T+ ++ DVND
Sbjct: 395 FQIKPSENHYSLLTSQPLDREATSHYIIELLA-SDAGSPSLHKHLTIRLNISDVNDNAPR 453
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-- 733
+ ++ I ++ G+ + + ++ + G+ ++ NQ +
Sbjct: 454 FNQQLYTAYI--LENRPPGSLLCTVAASDPDT--GDNARLTYSIVGNQVQGAPASSFVYV 509
Query: 734 --EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
EDG IF Q+ D E + ++ V+ + G + +++ DENDN P H
Sbjct: 510 NPEDGRIFAQRTFDYELLQMLQI-VVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPR 568
Query: 792 YEGFIMENSKIGTEIKMDNI---IKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVV 846
+ ++ ++ + A DAD G NA Y+L + +F V +TG V
Sbjct: 569 PDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEV 628
Query: 847 KFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEN 887
+ L+ + + LV RD G LSS A +++++ DE+
Sbjct: 629 RTARALLEDDSDTQQVVVLV-RDNGDPSLSSTATVLLVLEDED 670
Score = 86.6 bits (205), Expect = 5e-15
Identities = 68/218 (31%), Positives = 101/218 (46%), Gaps = 20/218 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN PIGT +++LNA D D G NGQ+ Y F +++A V+ F ++ G
Sbjct: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDH--------TSEA--VRNLFGLDPSSG 300
Query: 1000 --HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
HV+ + ++ A D G + + ++V V DVND+ P V
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVL 360
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV--NGELDRETE 1113
E+ V+G + D D G+N ++ I P DLPF+I P S+ + LDRE
Sbjct: 361 ESTPVGTVVGLFNVRDRDSGRNGEVSLDISP---DLPFQIKPSENHYSLLTSQPLDREAT 417
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
YI+ ++A D G DVNDN+P+F
Sbjct: 418 SHYIIELLASDAG-SPSLHKHLTIRLNISDVNDNAPRF 454
Score = 79.4 bits (187), Expect = 7e-13
Identities = 87/322 (27%), Positives = 147/322 (45%), Gaps = 32/322 (9%)
Query: 589 GTSVGQIRVNDAFEQNDV-SYDLLHGYEE-GVPFAVEERSGVITVVDDLSRYNRPMYDFE 646
GT VG + + + D+ S L G EE G F++ SG + V + R E
Sbjct: 42 GTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR--------E 93
Query: 647 AVALQENANLSIVTNATVHVVD-VNDERGVLLKGAHSPIIFHVKEN---SAGAAIGQIFH 702
++ + L V T H ++ + E +L +SP + S AA G F
Sbjct: 94 SLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASGARFP 153
Query: 703 TNMSSIYGNGTGNVRFL-IANQQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVI 757
+ + GT V F ++ + ++ +DG F + + LDRE + +++ V+
Sbjct: 154 LDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQL-VL 212
Query: 758 AEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA 817
+ G + +G +++ + D NDN P F+ + I EN+ IGT + + ATD
Sbjct: 213 TAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR---LNATDP 269
Query: 818 DEGTNALFMYTLFGEG-----KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
DEGTN Y+ FG+ + +F +D ++G + +G +D E+ Y++ ARD G
Sbjct: 270 DEGTNGQLDYS-FGDHTSEAVRNLFGLDPSSGAIHVLG-PIDFEESRFYEIHARARDQGQ 327
Query: 873 LSSEAELIIM--IGDENDNKPE 892
+ E +I +GD NDN PE
Sbjct: 328 PAMEGHCVIQVDVGDVNDNAPE 349
Score = 66.5 bits (155), Expect = 5e-09
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G Y L + L +G F E L+ + QA L + A
Sbjct: 157 AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR-HQLVLTAV 215
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ + + +LD+NDN P F+ + I EN P G +L++ ATD D+G NG
Sbjct: 216 DGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNG 275
Query: 340 EFTYQLDD-----PKGAFSIDPRSGWLTV 363
+ Y D + F +DP SG + V
Sbjct: 276 QLDYSFGDHTSEAVRNLFGLDPSSGAIHV 304
Score = 64.9 bits (151), Expect = 2e-08
Identities = 73/314 (23%), Positives = 131/314 (41%), Gaps = 29/314 (9%)
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
S R+ GL + I ++G + + F +I +++ R + + G + +V
Sbjct: 286 SEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEI--HARARDQGQPAMEGHCVIQV-DVGD 342
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
N A +V + E+ P+GT + N D DSG NG++ + + ++
Sbjct: 343 VNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDL--------- 393
Query: 984 DALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVN 1039
++K +E H ++ ++ L E S + + + A D G+ L+ ++++R+ + DVN
Sbjct: 394 -PFQIKP----SENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVN 448
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-----QPSDTDLPFE 1094
D+ P F + Y + E + +L V A+D D G NA LTY I Q +
Sbjct: 449 DNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVY 508
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
++P G + D E + V RD+G D NDN+P
Sbjct: 509 VNPEDGRIFAQRTFDYELLQMLQIVVGVRDSG-SPPLHANTSLHVFVLDENDNAPA--VL 565
Query: 1155 DELLEWKHPEADEL 1168
+W+H L
Sbjct: 566 HPRPDWEHSAPQRL 579
Score = 60.1 bits (139), Expect = 5e-07
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 10/177 (5%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G L Y S R LF LD +G++ + +D + ++ + +
Sbjct: 264 LNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE-----ESRFYEI 318
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+A P +++++ D+NDN PE + ++E+ P G V D+D
Sbjct: 319 HARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRD 378
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSV 390
G NGE + + P F I P ++ LDREA S +++ A + +PS+
Sbjct: 379 SGRNGEVSLDI-SPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSL 434
Score = 57.6 bits (133), Expect = 2e-06
Identities = 59/230 (25%), Positives = 98/230 (42%), Gaps = 12/230 (5%)
Query: 929 LDVDQLGPLFLIPEN-IPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALE 987
LD++ P F PE + I + LDS + + S + P+ S +L
Sbjct: 124 LDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPN--SHFSLN 181
Query: 988 VKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFP 1043
VK + +++ + L E++ R L ++A+DGG + + V V D+ND+ P
Sbjct: 182 VKT-LKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAP 240
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP---FEISPLTG 1100
F+ + + E +L +++ATD D G N L Y ++ F + P +G
Sbjct: 241 TFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSG 300
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+ V G +D E Y + ARD G DVNDN+P+
Sbjct: 301 AIHVLGPIDFEESRFYEIHARARDQG-QPAMEGHCVIQVDVGDVNDNAPE 349
Score = 54.8 bits (126), Expect = 2e-05
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 252 SLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFY 311
SL + LD +A + +++++ AS +P + + + D+NDN P F Y
Sbjct: 405 SLLTSQPLDREATSH-----YIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLY 459
Query: 312 NISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
I+EN P G + V A+D D G+N TY +
Sbjct: 460 TAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493
Score = 54.8 bits (126), Expect = 2e-05
Identities = 56/200 (28%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF-NSEVYIPPSKLSADALEVKRYFVINERH 998
I EN P G+ + + A D D+G N ++ Y ++V P+ + +N
Sbjct: 463 ILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPAS---------SFVYVNPED 513
Query: 999 GHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G + R+ E ++ + D G+ L+ N S+ VFV D ND+ P ++
Sbjct: 514 GRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEH 573
Query: 1055 EEAQYTRR------VLGKVDATDADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNG 1106
Q R ++ KV A DAD G NA L+Y + P T P F +S TG +
Sbjct: 574 SAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQST-APGLFLVSTHTGEVRTAR 632
Query: 1107 ELDRETEDKYILTVVARDNG 1126
L + D + V+ RDNG
Sbjct: 633 ALLEDDSDTQQVVVLVRDNG 652
Score = 53.2 bits (122), Expect = 5e-05
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 9/142 (6%)
Query: 221 IDQDLGVGAT----LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ QDLG+ T R +L S + + FSL ++G+L + +++D E A+T L
Sbjct: 48 VAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKID--RESLCGASTSCLLP 105
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+PL+ RVE+E+LDLNDN P F + I E+ +G A D D G
Sbjct: 106 VQVVTEHPLELI--RVEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVG 163
Query: 337 ENGEFTYQLDDPKGAFSIDPRS 358
N Y L P FS++ ++
Sbjct: 164 TNTVSFYTL-SPNSHFSLNVKT 184
Score = 47.6 bits (108), Expect = 0.003
Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 17/257 (6%)
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F +S ++G L+VN ++DRE+ + + D+NDNSP F
Sbjct: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134
Query: 1153 AFDELLEWKHPEAD----ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG 1208
+ + A L + V V T+ N+ V K + F
Sbjct: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNV-KTLKDGKPFPE 193
Query: 1209 NGNGLILYSLPQRKNQQNL-----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
L Q ++Q L G P+ S T ++ V V D+ D P F S
Sbjct: 194 LVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNA-----PTFQSSVLR 248
Query: 1264 LEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
+ I EN L+ LN T+ E N ++ Y + +R F +DP +G ++++
Sbjct: 249 VGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPI 308
Query: 1322 DREVKDTYEVIVRAERQ 1338
D E YE+ RA Q
Sbjct: 309 DFEESRFYEIHARARDQ 325
Score = 43.6 bits (98), Expect = 0.043
Identities = 92/385 (23%), Positives = 147/385 (38%), Gaps = 63/385 (16%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I V V + D+ND+ P F + E+ + A D D G N Y + P +
Sbjct: 117 IRVEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSP-N 175
Query: 1089 TDLPFEISPLTG-----VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
+ + L L + +LDRE + ++ L + A D G D
Sbjct: 176 SHFSLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGG-TPARSGTTLISVIVLD 234
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
+NDN+P F + V + I ENAPIGT + ++ A D
Sbjct: 235 INDNAPTFQS--------------------------SVLRVGIPENAPIGTLLLRLNATD 268
Query: 1204 TDFIGNGNGLILYSLPQRKNQ--QNLGLPSLSSTAILMVTVADVPD----EVEM----SD 1253
D NG + YS ++ +NL SS AI ++ D + E+
Sbjct: 269 PD--EGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQG 326
Query: 1254 KPVFISR-YYELEI-EENVNAPVELVSLNLTEHYENFKMRYYI--LNENDTDIRRTFVID 1309
+P ++++ + N NAP L++ E+ + + N D D
Sbjct: 327 QPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRD-------S 379
Query: 1310 PRNGTLYLVRSPDR--EVKDTYEVIVRAERQKYSRELP--HMIYPVAEDVLEGMTKYDVK 1365
RNG + L SPD ++K + Q RE ++I +A D +
Sbjct: 380 GRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLT 439
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTA 1390
+ + I DVNDN+P+F N+ L TA
Sbjct: 440 IRLNISDVNDNAPRF---NQQLYTA 461
Score = 40.3 bits (90), Expect = 0.40
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 444 NVEVTLLDANDNNP-VFVPSNLYEFS----MKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
++ V +LD NDN P V P +E S + +A G+++ KV AVD D G N + Y
Sbjct: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYS 608
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES 525
L S T F ++ +TG V A +
Sbjct: 609 LLPQS--TAPGLFLVSTHTGEVRTARA 633
>UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadherin
gamma B4 precursor (PCDH-gamma-B4) isoform 20; n=2;
Catarrhini|Rep: PREDICTED: similar to Protocadherin gamma
B4 precursor (PCDH-gamma-B4) isoform 20 - Pan troglodytes
Length = 749
Score = 99.1 bits (236), Expect = 8e-19
Identities = 149/576 (25%), Positives = 247/576 (42%), Gaps = 63/576 (10%)
Query: 589 GTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYN----RPMYD 644
G+ VG + + F ++ L E F V SG + V L R +P
Sbjct: 44 GSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACA 103
Query: 645 FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
E A+ EN L+ + V + D+ND + + I + +G +
Sbjct: 104 LEFEAVAENP-LNFY-HVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDAD 161
Query: 705 MSSIYGNG---TGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EF 760
+ S + + F + N++ +D E + + PLDREK+ Y +T+ A +F
Sbjct: 162 IGSNTLQNYQLSPSDHFSLINKEK-SDGSKYPE---MVLKTPLDREKQKSYHLTLTALDF 217
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+S Q+ + + D NDN PVF Y + EN GT + + ATD DEG
Sbjct: 218 GAPPLSSTA--QIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQ---VTATDQDEG 272
Query: 821 TNALFMYTLFGEGKEM--FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
NA ++ F E ++ FD++ NTG + + ++LD E+ Y + L ARD GG+ ++
Sbjct: 273 VNAEITFS-FSEASQITQFDLNSNTGEITVL-NTLDFEEVKEYSIVLEARDGGGMIAQCT 330
Query: 879 LIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLF 938
+ + + DENDN PE I ++ I + +L GT +++V+ K D G +
Sbjct: 331 VEVEVIDENDNAPEV--IFQSLPNLIMEDAEL-GT-HIALLKVRDK-----DSRHNGEVT 381
Query: 939 L-IPENIPIGTTIIKLNALDL--DSGLNGQIRYEFNSEVYI-----PP----SKLSADAL 986
+ ++P N L D+ L+ + E+N V PP S ++
Sbjct: 382 CKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLSSSSSITLHIG 441
Query: 987 EVKRYFVINERHGHVI-VARSLPPESEFRLNISALDGGNLNDN-------ISVRVFVKDV 1038
+V + + +++ VA + PP + +SA D +L N +S+RV V D
Sbjct: 442 DVNDNAPVFSQSSYIVHVAENNPPGASIS-QVSASD-PDLGPNGQVSYCIVSLRVLVDDR 499
Query: 1039 NDHFP--VFKKTWYNFN-----VEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTD 1090
ND+ P ++ + + V A ++ KV A DAD G NA L+Y + Q S+
Sbjct: 500 NDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPG 559
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
L F + TG + L + L V RD G
Sbjct: 560 L-FSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGG 594
Score = 85.8 bits (203), Expect = 8e-15
Identities = 98/401 (24%), Positives = 170/401 (42%), Gaps = 30/401 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E ++F +V V + D ND+ P F N +E + +A+ GT A D D+G N +
Sbjct: 111 ENPLNFYHVNVEIEDINDHTPKFT-QNSFELQISESAQPGTRFILGSAHDADIGSNTLQN 169
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + + ++ + K + + V ++P+ + + L + A D A P S A
Sbjct: 170 YQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLS---STA 226
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
+ + VT + P F Y + NV GT+V Q+ D + V+ ++
Sbjct: 227 QIHVLVTDAND----NAPVFSQDIYRVSLSENVYPGTTVLQVTATD--QDEGVNAEITFS 280
Query: 614 YEEG---VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
+ E F + +G ITV++ L Y A ++ + V V+D N
Sbjct: 281 FSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEA-RDGGGMIAQCTVEVEVIDEN 339
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D ++ + +I +++ G I + + S + NG + + DV I
Sbjct: 340 DNAPEVIFQSLPNLI--MEDAELGTHIALLKVRDKDSRH-NGEVTCKL----EGDVPFKI 392
Query: 731 AIAEDGT--IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ T + T LDRE+ Y +TV A ++G + +T++I D NDN PVF
Sbjct: 393 LTSSRNTYKLVTDAVLDREQNPEYNITVTAR-DRGKPPLSSSSSITLHIGDVNDNAPVFS 451
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
++Y + EN+ G I + A+D D G N Y +
Sbjct: 452 QSSYIVHVAENNPPGASISQ---VSASDPDLGPNGQVSYCI 489
Score = 77.8 bits (183), Expect = 2e-12
Identities = 45/148 (30%), Positives = 74/148 (50%), Gaps = 3/148 (2%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G Y+L + L + + +GS + E L + Q ++ L + A
Sbjct: 157 AHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQ-KSYHLTLTAL 215
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ A++ + + D NDN P F D Y +S+ EN+ G +VLQV ATD+D+G N
Sbjct: 216 DFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNA 275
Query: 340 EFTYQLDDPK--GAFSIDPRSGWLTVRN 365
E T+ + F ++ +G +TV N
Sbjct: 276 EITFSFSEASQITQFDLNSNTGEITVLN 303
Score = 74.9 bits (176), Expect = 2e-11
Identities = 64/218 (29%), Positives = 103/218 (47%), Gaps = 24/218 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN+ GTT++++ A D D G+N +I + F+ +A ++ + F +N G
Sbjct: 251 LSENVYPGTTVLQVTATDQDEGVNAEITFSFS------------EASQITQ-FDLNSNTG 297
Query: 1000 HVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFP-VFKKTWYNFNVEE 1056
+ V +L E E+ + + A DGG + +V V V D ND+ P V ++ N +E+
Sbjct: 298 EITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMED 357
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI---SPLTGVLSVNGELDRETE 1113
A+ + + D D N +T ++ D+PF+I S T L + LDRE
Sbjct: 358 AELGTHI-ALLKVRDKDSRHNGEVTCKLEG---DVPFKILTSSRNTYKLVTDAVLDREQN 413
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +TV ARD G DVNDN+P F
Sbjct: 414 PEYNITVTARDRG-KPPLSSSSSITLHIGDVNDNAPVF 450
Score = 71.3 bits (167), Expect = 2e-10
Identities = 87/353 (24%), Positives = 146/353 (41%), Gaps = 38/353 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ GT I +A D D G N Y+ + + S ++ + + +Y
Sbjct: 142 ISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKY-------P 192
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ L E + + L ++ALD G L+ + V V D ND+ PVF + Y ++
Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLS 252
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E Y + +V ATD D G NA +T+ + F+++ TG ++V LD E +
Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKE 312
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFES 1175
Y + + ARD G D NDN+P+ F L +A EL H
Sbjct: 313 YSIVLEARDGG---GMIAQCTVEVEVIDENDNAPE-VIFQSLPNLIMEDA-ELGTH---- 363
Query: 1176 VMMIPVYKATIEENAPI-----GTTVAKVFANDTDFIGNGNGLIL--YSLPQRK---NQQ 1225
+ ++ V N + G K+ + + +L P+ +
Sbjct: 364 IALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTAR 423
Query: 1226 NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS 1278
+ G P LSS++ + + + DV D + PVF Y + + EN N P +S
Sbjct: 424 DRGKPPLSSSSSITLHIGDVND-----NAPVFSQSSYIVHVAEN-NPPGASIS 470
Score = 69.3 bits (162), Expect = 8e-10
Identities = 84/329 (25%), Positives = 143/329 (43%), Gaps = 38/329 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A DQD GV A + + + F L+S G + + LD + + + + ++
Sbjct: 264 VTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFE-----EVKEYSIVLE 318
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A + AQ VE+E++D NDN PE I+E+ G + + DKD
Sbjct: 319 ARDGGGMI--AQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRH 376
Query: 338 NGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFA 395
NGE T +L+ D R+ + V VLDRE + + V A++ P + + +
Sbjct: 377 NGEVTCKLEGDVPFKILTSSRNTYKLV-TDAVLDREQNPEYNITVTARDRGKPPLSSSSS 435
Query: 396 DSQRIAKWRRQPLETNAPL-EKTTYVF----PDKVGTKTENIEYYDEQL-----MSF--V 443
+ I + NAP+ +++Y+ + G + D L +S+ V
Sbjct: 436 ITLHIG-----DVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSYCIV 490
Query: 444 NVEVTLLDANDNNP-VFVP------SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
++ V + D NDN P V P S L++ ++ A+ G ++ KV AVD D G N +
Sbjct: 491 SLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRA-AEPGYLVTKVVAVDADSGHNAWLS 549
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAES 525
Y + + S + F + TG V A +
Sbjct: 550 YHVLQASEPGL---FSLGLRTGEVRTARA 575
Score = 66.5 bits (155), Expect = 5e-09
Identities = 148/599 (24%), Positives = 230/599 (38%), Gaps = 101/599 (16%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ IPE +P G+ + L A DL G + Q +P KL + K YF ++
Sbjct: 35 YRIPEEMPKGSVVGNL-ATDL--GFSVQ---------ELPTRKLRVSS--EKPYFTVSAE 80
Query: 998 HGHVIVARSLPPES------EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
G ++V+ L E L A+ LN V V ++D+NDH P F + +
Sbjct: 81 SGELLVSSRLDREEICGKKPACALEFEAVAENPLNF-YHVNVEIEDINDHTPKFTQNSFE 139
Query: 1052 FNVEEAQY--TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV----LSVN 1105
+ E+ TR +LG A DAD G N Y + PSD G + +
Sbjct: 140 LQISESAQPGTRFILGS--AHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLK 197
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
LDRE + Y LT+ A D G D NDN+P
Sbjct: 198 TPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVT-DANDNAP---------------- 240
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
V +Y+ ++ EN GTTV +V A D D N +S + Q
Sbjct: 241 ----------VFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQF 290
Query: 1226 NLGLPSLSSTAILMVTVADVPD---EVEMSDKPVFISR-YYELE-IEENVNAP-VELVSL 1279
+L + T + + +V + +E D I++ E+E I+EN NAP V SL
Sbjct: 291 DLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSL 350
Query: 1280 -NLTEHYENFKMRYYILNENDTDIRRTFVIDPR-NGTL-YLVRSPDREVKDTYEVIVRAE 1336
NL +L D D R + + G + + + + R +TY+++ A
Sbjct: 351 PNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSR---NTYKLVTDAV 407
Query: 1337 RQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAP 1396
+ + + I A D + + + I DVNDN+P F+ + + + P
Sbjct: 408 LDR-EQNPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSS--YIVHVAENNP 464
Query: 1397 FGYQVMQLKGA---IGHHPTASRTV---------RADTDELVFFERLSLNG--------- 1435
G + Q+ + +G + S + R D V + L +G
Sbjct: 465 PGASISQVSASDPDLGPNGQVSYCIVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPR 524
Query: 1436 -------LTSPQATDSDIGINADIRYQILNEQAP-RFAIDPVSGTVRVVAALA-RDAGR 1485
+T A D+D G NA + Y +L P F++ +G VR AL RDA R
Sbjct: 525 AAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVR 583
Score = 45.2 bits (102), Expect = 0.014
Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 10/150 (6%)
Query: 239 NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+++ F++ + +G L + LD + E + L+ +A NPL VEIE D
Sbjct: 70 SEKPYFTVSAESGELLVSSRLDRE-EICGKKPACALEFEAVA-ENPLNFYHVNVEIE--D 125
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI---- 354
+ND+ P+F + + + I E+ G + A D D G N YQL P FS+
Sbjct: 126 INDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQL-SPSDHFSLINKE 184
Query: 355 -DPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
S + + +T LDRE S + + A
Sbjct: 185 KSDGSKYPEMVLKTPLDREKQKSYHLTLTA 214
Score = 38.3 bits (85), Expect = 1.6
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
G +S+ S+T++I DVNDN P+F + Y V V E P G
Sbjct: 426 GKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPG 466
>UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep:
ENSANGP00000009575 - Anopheles gambiae str. PEST
Length = 1424
Score = 99.1 bits (236), Expect = 8e-19
Identities = 124/476 (26%), Positives = 200/476 (42%), Gaps = 51/476 (10%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
E + + P F + Y+ +K VGT + V A+D D N ++ Y L T
Sbjct: 5 EFSANQVENRKPTFNECDSYKPMLKEEQPVGTPVLHVNAIDQD--PNQIIEYSLMTTPGE 62
Query: 506 TITSPFKINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ F+I+ NTG ++ + PI E + V A+D + +L V +++
Sbjct: 63 RVR--FRIDKNTGEITTVHVFDRDEPIREKEIYISVRATDDGRPRLDDVCTLKVKIVDIN 120
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV 618
+ P F YE V ++ + VG I D + ++ + Y+LL +
Sbjct: 121 DNS-------PVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQSLPDSS 173
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH----VVDVNDERG 674
F + E +G++T+V + R Y A N V + V V++ N
Sbjct: 174 FFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVMESNKRSP 233
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD--IAI 732
K I+ + I IF N S + LI + + T+ +
Sbjct: 234 YFSKLPEETIVLNETFKDYSKPIA-IFEAN--SAIPEKPEVIFELIQGRTEETNSKHTFL 290
Query: 733 AED----GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
E TI K LD E Y +TV + + +I+ A + I + DEND PVF
Sbjct: 291 LEQLNNVATIKLGKALDYEIIAEYTLTVSVKNSDDLIAEA---VLKIQVLDENDIIPVFP 347
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLFGEGKEMFDVDENTGVV 846
T G ++EN GT++ ++KA D D GT N + Y E + +F +D TG +
Sbjct: 348 EMT-SGAVLENDPPGTQVM---VVKAYDLD-GTPANNIVSYRFEDESQHLFHIDNITGQI 402
Query: 847 KFIGDSLDREKKIMYKLSLVARD--------TGGLSSEAELI-IMIGDENDNKPEF 893
K + +LDRE+ Y+L +VA D G +S +L+ I + D+NDNKP F
Sbjct: 403 KTLA-ALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAF 457
Score = 99.1 bits (236), Expect = 8e-19
Identities = 128/488 (26%), Positives = 210/488 (43%), Gaps = 45/488 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V ++D NDN+PVF YE S+ + KV +G + A D D G N ++ Y+L +
Sbjct: 112 LKVKIVDINDNSPVFDKVR-YEESVAKDMKVNQRVGTISATDMDDGDNSLIKYEL--LQS 168
Query: 505 LTITSPFKINPNTGTVS-VAESPILEGRHALF-VEASDQPANPSERRYSLAVVTIEVTRG 562
L +S F+IN N G V+ V + G+H L V A + ++ V I V
Sbjct: 169 LPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVMES 228
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNV--GIGTSVGQIRVNDAF-EQNDVSYDLLHGYEEGV- 618
K + P F P E V + + N A E+ +V ++L+ G E
Sbjct: 229 NKRS----PYFSKLPEETIVLNETFKDYSKPIAIFEANSAIPEKPEVIFELIQGRTEETN 284
Query: 619 ---PFAVEERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERG 674
F +E+ + V T+ + + ++ V+++ + +L + V+D ND
Sbjct: 285 SKHTFLLEQLNNVATIKLGKALDYEIIAEYTLTVSVKNSDDLIAEAVLKIQVLDENDIIP 344
Query: 675 VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV-TDDIAIA 733
V + ++ + + G + + ++ N + RF +Q D+I
Sbjct: 345 VFPEMTSGAVL---ENDPPGTQVMVVKAYDLDGTPANNIVSYRFEDESQHLFHIDNIT-- 399
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFN--KGVISGAGIYQVT----IYIEDENDNPPVF 787
G I T LDRE+ D Y++ V+AE N + +T I + D+NDN P F
Sbjct: 400 --GQIKTLAALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAF 457
Query: 788 --EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM-FDVDENTG 844
+H EG + E+ I T +I+ T D +L YT+ + + F +D NTG
Sbjct: 458 TSQHFVVEG-VPEDENINTP-----VIEVTARDPDATSLLHYTIVSGNEGLAFKIDNNTG 511
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRI 904
+ I + LD E Y L +V D G A + I + + NDN P F + V I
Sbjct: 512 RIS-INNRLDYETVREYTL-IVQVDDGIFQDNATVSIKVKNVNDNPPRFTGLR---NVTI 566
Query: 905 HRETKLNG 912
ET +G
Sbjct: 567 PEETIPSG 574
Score = 64.5 bits (150), Expect = 2e-08
Identities = 57/216 (26%), Positives = 102/216 (47%), Gaps = 16/216 (7%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
N F+ +V+ + + D P+ + E P+GT ++ +NA+D D N I Y
Sbjct: 1 NSPPEFSANQVENRKPTFNECDSYKPM--LKEEQPVGTPVLHVNAIDQDP--NQIIEYSL 56
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLP-PESEFRLNISALDGGN--LND 1027
+ P + ++ K I H + R P E E +++ A D G L+D
Sbjct: 57 MTT----PGERVRFRID-KNTGEITTVH---VFDRDEPIREKEIYISVRATDDGRPRLDD 108
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
+++V + D+ND+ PVF K Y +V + + +G + ATD D G N+ + Y + S
Sbjct: 109 VCTLKVKIVDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQS 168
Query: 1088 DTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVA 1122
D F+I+ G++++ ++DR Y++ V A
Sbjct: 169 LPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRA 204
Score = 62.9 bits (146), Expect = 7e-08
Identities = 115/482 (23%), Positives = 206/482 (42%), Gaps = 46/482 (9%)
Query: 427 TKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD 486
T T +++ D+ + V +++ +LD ND PVF + ++ N GT + VKA D
Sbjct: 315 TLTVSVKNSDDLIAEAV-LKIQVLDENDIIPVF--PEMTSGAVLENDPPGTQVMVVKAYD 371
Query: 487 PD-LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPA 543
D N +V Y + S F I+ TG + + E + L V A D
Sbjct: 372 LDGTPANNIVSYRFEDESQHL----FHIDNITGQIKTLAALDREQTDSYQLKVVAEDNSP 427
Query: 544 NPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEF-WVGSNVGIGTSVGQIRVNDAFE 602
+ R +T + + P F + V + I T V ++ D
Sbjct: 428 SALYRNGKPNSITKLLFIKVMDKNDNKPAFTSQHFVVEGVPEDENINTPVIEVTARDPDA 487
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
+ + Y ++ G EG+ F ++ +G I++ + L + ++ + ++
Sbjct: 488 TSLLHYTIVSG-NEGLAFKIDNNTGRISINNRLDY--ETVREYTLIVQVDDGIFQDNATV 544
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
++ V +VND G + I S Q + ++ + + ++RF +
Sbjct: 545 SIKVKNVNDNPP-RFTGLRNVTIPEETIPSGCIMTVQAYDPDIEN--RSDPQHIRFFYVD 601
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDRE-----KRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
+ D D I I + G + ++ LDR+ KR + +T E G + A V I +
Sbjct: 602 EYD--DAIEIDDSGCLRLKRALDRDPPLGSKRWQFIITATDEDGAGKKTPA---TVIISL 656
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL-FMYTLFG----E 832
ED NDN P + T +EN G +K+ +A D DE N F +++ E
Sbjct: 657 EDINDNAPRLSN-TMPVVWVENRPPGLIVKL----RADDVDEPQNGPPFHFSIDPNARYE 711
Query: 833 GKEMFDV--DENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDEND 888
K+ F V +E +V+F DRE++ Y++ ++ RD+G +S+ + L ++IGD+ND
Sbjct: 712 IKKRFKVQGEELHALVEF-----DREEQKEYQIPILIRDSGEEPMSAVSMLHLVIGDDND 766
Query: 889 NK 890
NK
Sbjct: 767 NK 768
Score = 54.0 bits (124), Expect = 3e-05
Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Query: 218 IHAIDQDLGVGATLRYELISG-NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
++AIDQD + Y L++ +R F +D G + D D ++ + V
Sbjct: 41 VNAIDQD--PNQIIEYSLMTTPGERVRFRIDKNTGEITTVHVFDRDEP--IREKEIYISV 96
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+A+ P ++++++D+NDN P F+ Y S+ +++ V + ATD D G
Sbjct: 97 RATDDGRPRLDDVCTLKVKIVDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDG 156
Query: 337 ENGEFTYQL--DDPKGA-FSIDPRSGWLTVRNQTVLDREAHSSLRMKVY 382
+N Y+L P + F I+ +G +T+ Q H + ++ Y
Sbjct: 157 DNSLIKYELLQSLPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRAY 205
Score = 53.6 bits (123), Expect = 4e-05
Identities = 49/166 (29%), Positives = 84/166 (50%), Gaps = 15/166 (9%)
Query: 233 YELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
+ELI G N + F L+ +N ++ LD E + T + V+ N+
Sbjct: 273 FELIQGRTEETNSKHTFLLEQLNNVATIKLGKALDYEI-IAEYTLTVSVK----NSDDLI 327
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD 346
A+A ++I++LD ND +P F + + +++EN P G V+ V A D D N +Y+ +
Sbjct: 328 AEAVLKIQVLDENDIIPVFP-EMTSGAVLENDPPGTQVMVVKAYDLDGTPANNIVSYRFE 386
Query: 347 DP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
D + F ID +G ++ LDRE S ++KV A++ +PS +
Sbjct: 387 DESQHLFHIDNITG--QIKTLAALDREQTDSYQLKVVAEDNSPSAL 430
Score = 50.8 bits (116), Expect = 3e-04
Identities = 78/323 (24%), Positives = 131/323 (40%), Gaps = 21/323 (6%)
Query: 588 IGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFE- 646
+GT V + D + Y L+ E V F +++ +G IT V R + P+ + E
Sbjct: 34 VGTPVLHVNAIDQDPNQIIEYSLMTTPGERVRFRIDKNTGEITTVHVFDR-DEPIREKEI 92
Query: 647 --AVALQENA--NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFH 702
+V ++ L V V +VD+ND V K + + K+ +G I
Sbjct: 93 YISVRATDDGRPRLDDVCTLKVKIVDINDNSPVFDKVRYEESV--AKDMKVNQRVGTISA 150
Query: 703 TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFN 761
T+M G+ + L+ + D + +G + K +DR Y + V A N
Sbjct: 151 TDMDD--GDNSLIKYELLQSLPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLN 208
Query: 762 -KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDA-DE 819
+G +V I + + N P F E ++ N K I +A A E
Sbjct: 209 QQGEPVHHTDVEVKILVMESNKRSPYFSKLPEETIVL-NETFKDYSKPIAIFEANSAIPE 267
Query: 820 GTNALFMY----TLFGEGKEMFDVDE--NTGVVKFIGDSLDREKKIMYKLSLVARDTGGL 873
+F T K F +++ N +K +G +LD E Y L++ +++ L
Sbjct: 268 KPEVIFELIQGRTEETNSKHTFLLEQLNNVATIK-LGKALDYEIIAEYTLTVSVKNSDDL 326
Query: 874 SSEAELIIMIGDENDNKPEFNQI 896
+EA L I + DEND P F ++
Sbjct: 327 IAEAVLKIQVLDENDIIPVFPEM 349
Score = 48.8 bits (111), Expect = 0.001
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 942 ENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGH 1000
EN P GT ++ + A DLD + N + Y F E + ++K ++
Sbjct: 356 ENDPPGTQVMVVKAYDLDGTPANNIVSYRFEDESQ-HLFHIDNITGQIKTLAALDREQTD 414
Query: 1001 VIVARSLPPESEFRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQ 1058
+ + ++ + SAL ++I+ +F+K D ND+ P F T +F VE
Sbjct: 415 SYQLKVVAEDN----SPSALYRNGKPNSITKLLFIKVMDKNDNKPAF--TSQHFVVEGVP 468
Query: 1059 YTRRVLGKV-DATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+ V + T D + L Y I + L F+I TG +S+N LD ET +Y
Sbjct: 469 EDENINTPVIEVTARDPDATSLLHYTIVSGNEGLAFKIDNNTGRISINNRLDYETVREYT 528
Query: 1118 LTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L +V D+G +VNDN P+F
Sbjct: 529 L-IVQVDDG---IFQDNATVSIKVKNVNDNPPRF 558
Score = 47.2 bits (107), Expect = 0.003
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 1011 SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+E+ L +S + +L +++ V D ND PVF + +E +V+ V A
Sbjct: 312 AEYTLTVSVKNSDDLIAEAVLKIQVLDENDIIPVFPEMTSGAVLENDPPGTQVM-VVKAY 370
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
D D N+ + ++ F I +TG + LDRE D Y L VVA DN
Sbjct: 371 DLDGTPANNIVSYRFEDESQHLFHIDNITGQIKTLAALDREQTDSYQLKVVAEDN 425
Score = 46.4 bits (105), Expect = 0.006
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 31/242 (12%)
Query: 142 KDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKP----VLLLRKVLDYDAGDKEF 197
K + A DR++ +D + V D+ AL + KP LL KV+D + F
Sbjct: 403 KTLAALDREQ-----TDSYQLKVVAEDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAF 457
Query: 198 QLV-IMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
+ G + I P I +D + L Y ++SGN+ F +D+ G + +
Sbjct: 458 TSQHFVVEGVPEDENINTPV-IEVTARDPDATSLLHYTIVSGNEGLAFKIDNNTGRISIN 516
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISI- 315
LD + ++ T ++QV ++ + A V I++ ++NDN P F N++I
Sbjct: 517 NRLDYE---TVREYTLIVQV-----DDGIFQDNATVSIKVKNVNDNPPRF-TGLRNVTIP 567
Query: 316 VENLPNGFSVLQVMATDKD-----QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLD 370
E +P+G ++ V A D D ++ F Y +D+ A ID SG L R + LD
Sbjct: 568 EETIPSG-CIMTVQAYDPDIENRSDPQHIRFFY-VDEYDDAIEIDD-SGCL--RLKRALD 622
Query: 371 RE 372
R+
Sbjct: 623 RD 624
Score = 45.2 bits (102), Expect = 0.014
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 15/143 (10%)
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--F 837
EN P E +Y+ + E +GT + N I D+ N + Y+L E F
Sbjct: 12 ENRKPTFNECDSYKPMLKEEQPVGTPVLHVNAI-----DQDPNQIIEYSLMTTPGERVRF 66
Query: 838 DVDENTGVVKFIGDSLDREKKIMYK---LSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+D+NTG + + DR++ I K +S+ A D G L L + I D NDN P
Sbjct: 67 RIDKNTGEITTV-HVFDRDEPIREKEIYISVRATDDGRPRLDDVCTLKVKIVDINDNSPV 125
Query: 893 FNQIEENSKVRIHRETKLNGTAG 915
F+++ V ++ K+N G
Sbjct: 126 FDKVRYEESVA--KDMKVNQRVG 146
Score = 41.5 bits (93), Expect = 0.17
Identities = 65/262 (24%), Positives = 103/262 (39%), Gaps = 27/262 (10%)
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKN--KFALDVDQLGPLFLIPENIPIGTTIIKLN 954
E+NS ++R K N I+V KN K A Q + +PE+ I T +I++
Sbjct: 423 EDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAF-TSQHFVVEGVPEDENINTPVIEVT 481
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--E 1012
A D D+ + Y S + L K I+ G + + L E+ E
Sbjct: 482 ARDPDA--TSLLHYTIVS---------GNEGLAFK----IDNNTGRISINNRLDYETVRE 526
Query: 1013 FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
+ L I +D G DN +V + VK+VND+ P F N + E + V A D
Sbjct: 527 YTL-IVQVDDGIFQDNATVSIKVKNVNDNPPRFTGL-RNVTIPEETIPSGCIMTVQAYDP 584
Query: 1073 DFGQNANLTY--FIQPSDTDLPFEISPLTGVLSVNGELDRETE--DKYILTVVARDNGXX 1128
D ++ + F + D EI +G L + LDR+ K ++ +
Sbjct: 585 DIENRSDPQHIRFFYVDEYDDAIEIDD-SGCLRLKRALDRDPPLGSKRWQFIITATDEDG 643
Query: 1129 XXXXXXXXXXXXXXDVNDNSPK 1150
D+NDN+P+
Sbjct: 644 AGKKTPATVIISLEDINDNAPR 665
Score = 41.5 bits (93), Expect = 0.17
Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 12/126 (9%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVD 309
+G L L++ LD D + F+ + A+ + K A V I L D+NDN P +
Sbjct: 612 SGCLRLKRALDRDPPLGSKRWQFI--ITATDEDGAGKKTPATVIISLEDINDNAPRLS-N 668
Query: 310 FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVL 369
+ VEN P G ++++ A D D+ +NG P FSIDP + + + V
Sbjct: 669 TMPVVWVENRPPGL-IVKLRADDVDEPQNG--------PPFHFSIDPNARYEIKKRFKVQ 719
Query: 370 DREAHS 375
E H+
Sbjct: 720 GEELHA 725
>UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor
(PCDH-gamma-C3) (Protocadherin 43) (PC-43)
(Protocadherin 2).; n=2; Xenopus tropicalis|Rep:
Protocadherin gamma C3 precursor (PCDH-gamma-C3)
(Protocadherin 43) (PC-43) (Protocadherin 2). - Xenopus
tropicalis
Length = 932
Score = 98.3 bits (234), Expect = 1e-18
Identities = 111/479 (23%), Positives = 209/479 (43%), Gaps = 34/479 (7%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S + + V +LDANDN+P F + Y +K NA +++ K+ A D D G NG + Y
Sbjct: 226 STMQINVIVLDANDNHPAFDQPS-YNVQLKENAPKNSLVIKLNATDLDEGPNGEIEYFFS 284
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE 558
++ +++ F++N TG + V + E + + +EA D+ E S+ V I+
Sbjct: 285 SHNSDALSNIFQLNSETGEIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIID 344
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V T P+ + + V + GT V I + D + + + + ++ +
Sbjct: 345 VNDNT-------PEMTISAFSSSVPEDSPAGTVVAVITIKD--KDHGDNGRVQCQVDKNI 395
Query: 619 PFAVE---ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDER 673
PF V E + D+L R + Y + ++ N + T + VV DVND
Sbjct: 396 PFTVREDFEHQFSLITSDNLDRESVSEYHI-TITAKDMGNPPLSTEKVISVVVSDVNDNA 454
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI- 732
++ + +F + N AG + + ++ + N + + ++D I
Sbjct: 455 PQFVEPVYE--VFVEENNKAGELLCTVSASD-PDLDQNSRLSYTIIQNPKEDYASSSHIY 511
Query: 733 --AEDGTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
+E+G ++ + PLD E+ + +R + +A+ + + V +++ D+NDN PV
Sbjct: 512 INSENGQVYLKFPLDYERINYFRFQIEVADAGSPPLKNKTV--VHVFVLDQNDNAPVVVF 569
Query: 790 ATYEGFIMENSKI----GTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
+ + KI G + M + I A D D G NA Y L +F V TG
Sbjct: 570 PIVGANSVAHCKIPLLTGPNV-MVSKISAVDYDSGRNAWLSYNLLDATDPTLFSVVLRTG 628
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
+K D + I ++L L+ +D+G + +M+ E+ + ++++SK R
Sbjct: 629 EIKTKRAIQDIDPTI-HELLLLVKDSGDPCLSTSVTVMMTLEDKDLEISQGVKDHSKKR 686
Score = 91.1 bits (216), Expect = 2e-16
Identities = 103/478 (21%), Positives = 192/478 (40%), Gaps = 36/478 (7%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N+++ E + +EV +LD NDN+P F L + A G A DPD+G
Sbjct: 107 NLKFAIENPVEVYRIEVEILDINDNSPRFQGDEL-TLKINELASPGARFLIPNAQDPDIG 165
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSE 547
N + Y L + N + + + + + E + + H L ++A D
Sbjct: 166 SNALQEYHLSPSENFALIVKKRTDGSKFPELILEKALDREQTAVHHLVLKAEDGGVPSRS 225
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
+ V+ ++ + P F Y + N + V ++ D E +
Sbjct: 226 STMQINVIVLDA-------NDNHPAFDQPSYNVQLKENAPKNSLVIKLNATDLDEGPNGE 278
Query: 606 VSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNA 662
+ Y + + F + +G I V+ +L +Y+ + A + + +
Sbjct: 279 IEYFFSSHNSDALSNIFQLNSETGEIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSV 338
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
VH++DVND + A S + +++ AG + I T +G+ G V+ +
Sbjct: 339 IVHIIDVNDNTPEMTISAFSSSV--PEDSPAGTVVAVI--TIKDKDHGD-NGRVQCQVDK 393
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDEN 781
T ++ T LDRE Y +T+ A + +S + +++ + D N
Sbjct: 394 NIPFTVREDFEHQFSLITSDNLDRESVSEYHITITAKDMGNPPLSTEKV--ISVVVSDVN 451
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD--- 838
DN P F YE F+ EN+K G ++ + A+D D N+ YT+ KE +
Sbjct: 452 DNAPQFVEPVYEVFVEENNKAG---ELLCTVSASDPDLDQNSRLSYTIIQNPKEDYASSS 508
Query: 839 ---VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
++ G V ++ LD E+ ++ + D G L ++ + + + D+NDN P
Sbjct: 509 HIYINSENGQV-YLKFPLDYERINYFRFQIEVADAGSPPLKNKTVVHVFVLDQNDNAP 565
Score = 87.0 bits (206), Expect = 3e-15
Identities = 101/387 (26%), Positives = 167/387 (43%), Gaps = 32/387 (8%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G + NA D D G N Y ++ PS+ A L VK+ + +I+ ++
Sbjct: 151 GARFLIPNAQDPDIGSNALQEY------HLSPSENFA--LIVKKR-TDGSKFPELILEKA 201
Query: 1007 LPPESE--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E L + A DGG + + + + V V D ND+ P F + YN ++E
Sbjct: 202 LDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQLKENAPKNS 261
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDL---PFEISPLTGVLSVNGELDRETEDKYILT 1119
++ K++ATD D G N + YF ++D F+++ TG + V G LD E Y +
Sbjct: 262 LVIKLNATDLDEGPNGEIEYFFSSHNSDALSNIFQLNSETGEIRVLGNLDFEEVSVYEID 321
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPK--FYAFDELLEWKHPEADELSNHNFESVM 1177
+ ARD G DVNDN+P+ AF + P ++ +
Sbjct: 322 IEARDKG-TPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVPEDSPAGTVVAVITIKDKD 380
Query: 1178 MIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRK---NQQNLGLPSLSS 1234
+ + + I TV + F + I + N L S+ + +++G P LS+
Sbjct: 381 HGDNGRVQCQVDKNIPFTVREDFEHQFSLITSDN-LDRESVSEYHITITAKDMGNPPLST 439
Query: 1235 TAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL--VSLNLTEHYENFKMRY 1292
++ V V+DV D + P F+ YE+ +EEN A L VS + + +N ++ Y
Sbjct: 440 EKVISVVVSDVND-----NAPQFVEPVYEVFVEENNKAGELLCTVSASDPDLDQNSRLSY 494
Query: 1293 YILNENDTDIRRT--FVIDPRNGTLYL 1317
I+ D + I+ NG +YL
Sbjct: 495 TIIQNPKEDYASSSHIYINSENGQVYL 521
Score = 84.6 bits (200), Expect = 2e-14
Identities = 67/219 (30%), Positives = 104/219 (47%), Gaps = 21/219 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P + +IKLNA DLD G NG+I Y F+S ++DAL F +N G
Sbjct: 253 LKENAPKNSLVIKLNATDLDEGPNGEIEYFFSSH--------NSDAL--SNIFQLNSETG 302
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ V +L E S + ++I A D G + ++ SV V + DVND+ P + ++ +V
Sbjct: 303 EIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVP 362
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS---PLTGVLSVNGELDRET 1112
E V+ + D D G N + + D ++PF + L + LDRE+
Sbjct: 363 EDSPAGTVVAVITIKDKDHGDNGRVQCQV---DKNIPFTVREDFEHQFSLITSDNLDRES 419
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +T+ A+D G DVNDN+P+F
Sbjct: 420 VSEYHITITAKDMG-NPPLSTEKVISVVVSDVNDNAPQF 457
Score = 78.6 bits (185), Expect = 1e-12
Identities = 69/235 (29%), Positives = 114/235 (48%), Gaps = 23/235 (9%)
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
+ +K LDRE+ V+ + + AE + GV S + Q+ + + D NDN P F+ +Y +
Sbjct: 196 LILEKALDREQTAVHHLVLKAE-DGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQLK 254
Query: 798 ENS-KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDS 852
EN+ K IK++ ATD DEG N Y + +F ++ TG ++ +G +
Sbjct: 255 ENAPKNSLVIKLN----ATDLDEGPNGEIEYFFSSHNSDALSNIFQLNSETGEIRVLG-N 309
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKL 910
LD E+ +Y++ + ARD G + +I+ I D NDN PE +S V E
Sbjct: 310 LDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSV---PEDSP 366
Query: 911 NGTAGFTIIEVKPKN-----KFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDS 960
GT +I +K K+ + VD+ P F + E+ ++I + LD +S
Sbjct: 367 AGTV-VAVITIKDKDHGDNGRVQCQVDKNIP-FTVREDFEHQFSLITSDNLDRES 419
Score = 66.9 bits (156), Expect = 4e-09
Identities = 74/331 (22%), Positives = 133/331 (40%), Gaps = 26/331 (7%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFI------------FLIA 122
N + Y + V I D+NDN P F + ++EL G + I
Sbjct: 114 NPVEVY-RIEVEILDINDNSPRFQGDELTLKINELASPGARFLIPNAQDPDIGSNALQEY 172
Query: 123 PIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHK-PV 181
+ PS L V + K + + VH+ ++ D G + S+ + V
Sbjct: 173 HLSPSENFALIVKKRTDGSKFPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINV 232
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
++L ++ A D+ V + + ++ ++A D D G + Y S N
Sbjct: 233 IVLDANDNHPAFDQPSYNVQLKENAPKNSLVI---KLNATDLDEGPNGEIEYFFSSHNSD 289
Query: 242 KL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
L F L+S G + + LD + + + + + ++A P+ V + ++D
Sbjct: 290 ALSNIFQLNSETGEIRVLGNLDFE-----EVSVYEIDIEARDKGTPIMEEHCSVIVHIID 344
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
+NDN PE + ++ S+ E+ P G V + DKD G+NG Q+D +
Sbjct: 345 VNDNTPEMTISAFSSSVPEDSPAGTVVAVITIKDKDHGDNGRVQCQVDKNIPFTVREDFE 404
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKET-NP 388
++ LDRE+ S + + AK+ NP
Sbjct: 405 HQFSLITSDNLDRESVSEYHITITAKDMGNP 435
Score = 64.9 bits (151), Expect = 2e-08
Identities = 62/216 (28%), Positives = 95/216 (43%), Gaps = 19/216 (8%)
Query: 704 NMSSIYGN-----GTGNVRFLIANQQDVTDD----IAI-AEDGTIFTQKPLDREKRDVYR 753
N I GN GT + + AN Q ++D +I +G I +DRE
Sbjct: 42 NRGEIVGNIAKDLGTDVAKLVAANLQVLSDSDSQYFSINVNNGAILVNDRIDRELLCAQS 101
Query: 754 MTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIK 813
+T I + + +Y++ + I D NDN P F+ I E + G + N
Sbjct: 102 VTCILNLKFAIENPVEVYRIEVEILDINDNSPRFQGDELTLKINELASPGARFLIPN--- 158
Query: 814 ATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGDSLDREKKIMYKLSLVARD 869
A D D G+NAL Y L V + T KF + +LDRE+ ++ L L A D
Sbjct: 159 AQDPDIGSNALQEYHLSPSENFALIVKKRTDGSKFPELILEKALDREQTAVHHLVLKAED 218
Query: 870 TG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
G SS ++ +++ D NDN P F+Q N +++
Sbjct: 219 GGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQLK 254
Score = 59.7 bits (138), Expect = 6e-07
Identities = 46/149 (30%), Positives = 71/149 (47%), Gaps = 17/149 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ P GT + + D D G NG+++ + + + V+ F E
Sbjct: 361 VPEDSPAGTVVAVITIKDKDHGDNGRVQCQVDKNI----------PFTVREDF---EHQF 407
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+I + +L ES E+ + I+A D GN L+ + V V DVND+ P F + Y VE
Sbjct: 408 SLITSDNLDRESVSEYHITITAKDMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVE 467
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFI 1084
E +L V A+D D QN+ L+Y I
Sbjct: 468 ENNKAGELLCTVSASDPDLDQNSRLSYTI 496
Score = 54.8 bits (126), Expect = 2e-05
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 9/151 (5%)
Query: 208 IHKEILFPEPIHAIDQDLGVGAT----LRYELISGNDRKLFSLDSVNGSLFLEKELDLDA 263
I +E+ E + I +DLG +++S +D + FS++ NG++ + +D +
Sbjct: 37 IPEELNRGEIVGNIAKDLGTDVAKLVAANLQVLSDSDSQYFSINVNNGAILVNDRIDREL 96
Query: 264 EHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF 323
Q+ T +L ++ + + NP++ R+E+E+LD+NDN P F+ D + I E G
Sbjct: 97 LC-AQSVTCILNLKFA-IENPVEVY--RIEVEILDINDNSPRFQGDELTLKINELASPGA 152
Query: 324 SVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
L A D D G N Y L P F++
Sbjct: 153 RFLIPNAQDPDIGSNALQEYHL-SPSENFAL 182
Score = 52.0 bits (119), Expect = 1e-04
Identities = 74/324 (22%), Positives = 130/324 (40%), Gaps = 37/324 (11%)
Query: 1087 SDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
SD+D F I+ G + VN +DRE +T + D+N
Sbjct: 70 SDSDSQYFSINVNNGAILVNDRIDRELLCAQSVTCILNLKFAIENPVEVYRIEVEILDIN 129
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE-NAPIGTTVAKVFANDT 1204
DNSP+F DEL + A + + + ++E + A + T
Sbjct: 130 DNSPRFQG-DELTLKINELASPGARFLIPNAQDPDIGSNALQEYHLSPSENFALIVKKRT 188
Query: 1205 DFIGNGNGLILYSLPQRKNQ--------QNLGLPSLSSTAILMVTVADVPDEVEMSDKPV 1256
D ++ +L + + ++ G+PS SST + V V D D + P
Sbjct: 189 DGSKFPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDAND-----NHPA 243
Query: 1257 FISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGT 1314
F Y ++++EN ++ LN T+ E N ++ Y+ + N + F ++ G
Sbjct: 244 FDQPSYNVQLKENAPKNSLVIKLNATDLDEGPNGEIEYFFSSHNSDALSNIFQLNSETGE 303
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVN 1374
+ ++ + D E YE+ + A R K + P+ E+ V+V I DVN
Sbjct: 304 IRVLGNLDFEEVSVYEIDIEA-RDKGT--------PIMEE--------HCSVIVHIIDVN 346
Query: 1375 DNSPKFTNGNRPLVTAIPTTAPFG 1398
DN+P+ T +++P +P G
Sbjct: 347 DNTPEMTIS--AFSSSVPEDSPAG 368
Score = 49.2 bits (112), Expect = 9e-04
Identities = 80/367 (21%), Positives = 145/367 (39%), Gaps = 33/367 (8%)
Query: 37 AQSIDSLVDSDSPQNVVKFRLGCDFDEGD----DLVRIGAGLNQISAYLSVTVYIEDVND 92
+ ++ ++ +S ++ DF+E D+ G + + SV V+I DVND
Sbjct: 288 SDALSNIFQLNSETGEIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVND 347
Query: 93 NVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVPRGL--TIFKDIR--- 145
N P + + +V E +P G + I G + + V + + T+ +D
Sbjct: 348 NTPEMTISAFSSSVPEDSPAGTVVAVITIKDKDHGDNGRVQCQVDKNIPFTVREDFEHQF 407
Query: 146 -AFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMAS 204
D + + ++ ++ D G+ L + +++ V D E +
Sbjct: 408 SLITSDNLDRESVSEYHITITAKDMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVE 467
Query: 205 GKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS-----LDSVNGSLFLEKEL 259
E+L + A D DL + L Y +I S ++S NG ++L+ L
Sbjct: 468 ENNKAGELLCT--VSASDPDLDQNSRLSYTIIQNPKEDYASSSHIYINSENGQVYLKFPL 525
Query: 260 DLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN- 318
D + + N F Q++ + +P + V + +LD NDN P + V +
Sbjct: 526 DYE-----RINYFRFQIEVADAGSPPLKNKTVVHVFVLDQNDNAPVVVFPIVGANSVAHC 580
Query: 319 ---LPNGFSVL--QVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWL-TVRNQTVLD 370
L G +V+ ++ A D D G N +Y L D FS+ R+G + T R +D
Sbjct: 581 KIPLLTGPNVMVSKISAVDYDSGRNAWLSYNLLDATDPTLFSVVLRTGEIKTKRAIQDID 640
Query: 371 REAHSSL 377
H L
Sbjct: 641 PTIHELL 647
Score = 40.7 bits (91), Expect = 0.30
Identities = 46/197 (23%), Positives = 79/197 (40%), Gaps = 18/197 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G + ++A D D N ++ Y + P ++ + + IN +G
Sbjct: 466 VEENNKAGELLCTVSASDPDLDQNSRLSYTI---IQNPKEDYASSS-----HIYINSENG 517
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN-- 1053
V + L E + FR I D G+ L + V VFV D ND+ PV N
Sbjct: 518 QVYLKFPLDYERINYFRFQIEVADAGSPPLKNKTVVHVFVLDQNDNAPVVVFPIVGANSV 577
Query: 1054 ----VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
+ ++ K+ A D D G+NA L+Y + + F + TG + +
Sbjct: 578 AHCKIPLLTGPNVMVSKISAVDYDSGRNAWLSYNLLDATDPTLFSVVLRTGEIKTKRAIQ 637
Query: 1110 RETEDKYILTVVARDNG 1126
+ L ++ +D+G
Sbjct: 638 DIDPTIHELLLLVKDSG 654
>UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor
(PCDH-beta11).; n=9; Xenopus tropicalis|Rep:
Protocadherin beta 11 precursor (PCDH-beta11). - Xenopus
tropicalis
Length = 795
Score = 98.3 bits (234), Expect = 1e-18
Identities = 110/473 (23%), Positives = 191/473 (40%), Gaps = 27/473 (5%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
N++ E + +++V + D NDN P F P N + + +A G G A DPDLG
Sbjct: 106 NLKAMIENPLQIFSIKVEIQDINDNAPSF-PKNSLKIVISESALPGVRFGLGYAQDPDLG 164
Query: 491 QNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRY 550
N + Y L T++ I + + + L+ +E S A+ R
Sbjct: 165 INSVQSYGLS-TNDYFILGERTSSDGSKYPELVLEKSLDREQQSSIELS-LSASDGGRPM 222
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSY 608
I + + P F Y+ + NV SV QI+ D E ++Y
Sbjct: 223 KTGTTLIRIV--VYDANDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITY 280
Query: 609 DLLHGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
H E + F+++ ++G IT + DL Y V ++ L ++ V+
Sbjct: 281 SFTHIPENALHIFSIDSQTGQITKIGDLDYEVTKKYTL-TVEAKDGGELVSHCKVSIQVI 339
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
D ND + + + V E+S + I + + + G V I
Sbjct: 340 DANDNAPEIQINS---FLGTVPEDSPPETVIAIIYVH--DLDSGENGEVVCQIPENLPFQ 394
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ T +DRE+ Y +++ A+ +KG S + + + + + D NDN PVF
Sbjct: 395 LITLTESYYKLVTLSRMDRERTSEYNISITAK-DKGTPSLSSLKTIRVALTDVNDNIPVF 453
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN----- 842
E Y ++ EN++ G I + A D D N Y++ + + +
Sbjct: 454 EKTHYVTYVPENNQPGMSILH---VNALDFDINDNGFITYSVISTAIQNIPISSHVSINS 510
Query: 843 -TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE 892
TGV+ + + D E+ ++ ++A D G LSS + + + I D+NDN PE
Sbjct: 511 ATGVI-YALHAFDYEQIREFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAPE 562
Score = 94.3 bits (224), Expect = 2e-17
Identities = 61/171 (35%), Positives = 88/171 (51%), Gaps = 7/171 (4%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
+A D DLG+ + Y L + + L S +GS + E L+ + Q ++ L + A
Sbjct: 157 YAQDPDLGINSVQSYGLSTNDYFILGERTSSDGSKYPELVLEKSLDRE-QQSSIELSLSA 215
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S P+KT + I + D NDN P F D Y ++I EN+ N FSVLQ+ ATD D+G N
Sbjct: 216 SDGGRPMKTGTTLIRIVVYDANDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGAN 275
Query: 339 GEFTYQLDD-PKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+ TY P+ A FSID ++G +T LD E + V AK+
Sbjct: 276 GQITYSFTHIPENALHIFSIDSQTGQITKIGD--LDYEVTKKYTLTVEAKD 324
Score = 79.8 bits (188), Expect = 5e-13
Identities = 94/363 (25%), Positives = 150/363 (41%), Gaps = 35/363 (9%)
Query: 986 LEVKRYFVINER-------HGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVF 1034
L YF++ ER + +++ +SL E S L++SA DGG +R+
Sbjct: 173 LSTNDYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIV 232
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ--PSDTDLP 1092
V D ND+ PVF + Y N+ E + ++ ATD D G N +TY P +
Sbjct: 233 VYDANDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFTHIPENALHI 292
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F I TG ++ G+LD E KY LTV A+D G D NDN+P+
Sbjct: 293 FSIDSQTGQITKIGDLDYEVTKKYTLTVEAKDGG---ELVSHCKVSIQVIDANDNAPEIQ 349
Query: 1153 A---FDELLEWKHPEA--DELSNHNFESVMMIPVYKATIEENAP--IGTTVAKVFANDTD 1205
+ E PE + H+ +S V I EN P + T + T
Sbjct: 350 INSFLGTVPEDSPPETVIAIIYVHDLDSGENGEVV-CQIPENLPFQLITLTESYYKLVTL 408
Query: 1206 FIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
+ Y++ ++ G PSLSS + V + DV D + PVF +Y
Sbjct: 409 SRMDRERTSEYNI--SITAKDKGTPSLSSLKTIRVALTDVNDNI-----PVFEKTHYVTY 461
Query: 1266 IEENVNAPVELVSLNLTEH--YENFKMRYYILNE--NDTDIRRTFVIDPRNGTLYLVRSP 1321
+ EN + ++ +N + +N + Y +++ + I I+ G +Y + +
Sbjct: 462 VPENNQPGMSILHVNALDFDINDNGFITYSVISTAIQNIPISSHVSINSATGVIYALHAF 521
Query: 1322 DRE 1324
D E
Sbjct: 522 DYE 524
Score = 75.8 bits (178), Expect = 9e-12
Identities = 61/217 (28%), Positives = 94/217 (43%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN+ +++++ A D+D G NGQI Y F +IP + L F I+ + G
Sbjct: 252 IYENVANNFSVLQIQATDIDEGANGQITYSFT---HIPENAL--------HIFSIDSQTG 300
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ L E ++ L + A DGG L + V + V D ND+ P + + V E
Sbjct: 301 QITKIGDLDYEVTKKYTLTVEAKDGGELVSHCKVSIQVIDANDNAPEIQINSFLGTVPED 360
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
V+ + D D G+N + I +LPF++ LT L +DRE
Sbjct: 361 SPPETVIAIIYVHDLDSGENGEVVCQI---PENLPFQLITLTESYYKLVTLSRMDRERTS 417
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +++ A+D G DVNDN P F
Sbjct: 418 EYNISITAKDKG-TPSLSSLKTIRVALTDVNDNIPVF 453
Score = 68.5 bits (160), Expect = 1e-09
Identities = 67/241 (27%), Positives = 107/241 (44%), Gaps = 23/241 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
I+V N A ++ L +PE+ P T I + DLDSG NG++ + + P
Sbjct: 336 IQVIDANDNAPEIQINSFLGTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIPENL---P 392
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLNDNISVRVF 1034
+L + E + ++ + E SE+ ++I+A D G +L+ ++RV
Sbjct: 393 FQL----------ITLTESYYKLVTLSRMDRERTSEYNISITAKDKGTPSLSSLKTIRVA 442
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPF 1093
+ DVND+ PVF+KT Y V E + V+A D D N +TY I + ++P
Sbjct: 443 LTDVNDNIPVFEKTHYVTYVPENNQPGMSILHVNALDFDINDNGFITYSVISTAIQNIPI 502
Query: 1094 ----EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
I+ TGV+ D E ++ V+A DNG D NDN+P
Sbjct: 503 SSHVSINSATGVIYALHAFDYEQIREFQFQVMATDNG-SPSLSSNSTIRVCIIDKNDNAP 561
Query: 1150 K 1150
+
Sbjct: 562 E 562
Score = 60.5 bits (140), Expect = 3e-07
Identities = 66/275 (24%), Positives = 116/275 (42%), Gaps = 28/275 (10%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
I A D D G + Y I N +FS+DS G + K DLD E + L
Sbjct: 265 IQATDIDEGANGQITYSFTHIPENALHIFSIDSQTGQI--TKIGDLDYE---VTKKYTLT 319
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A + + +V I+++D NDN PE +++ + ++ E+ P + + D D
Sbjct: 320 VEAKDGGELV--SHCKVSIQVIDANDNAPEIQINSFLGTVPEDSPPETVIAIIYVHDLDS 377
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTF 394
GENGE Q+ + I + + + +DRE S + + AK+ PS+
Sbjct: 378 GENGEVVCQIPENLPFQLITLTESYYKLVTLSRMDRERTSEYNISITAKDKGTPSL---- 433
Query: 395 ADSQRIAKWRRQPLETNAPL-EKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
S + + + N P+ EKT YV + ++ MS ++V D N
Sbjct: 434 -SSLKTIRVALTDVNDNIPVFEKTHYV---------TYVPENNQPGMSILHVNALDFDIN 483
Query: 454 DNNPV---FVPSNLYEFSMKSNAKVGTVIGKVKAV 485
DN + + + + + S+ + + G + A+
Sbjct: 484 DNGFITYSVISTAIQNIPISSHVSINSATGVIYAL 518
Score = 59.3 bits (137), Expect = 8e-07
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN G +I+ +NALD D NG I Y S + + + + IN G
Sbjct: 462 VPENNQPGMSILHVNALDFDINDNGFITYSVIST--------AIQNIPISSHVSINSATG 513
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK--------K 1047
+ + E EF+ + A D G+ L+ N ++RV + D ND+ P
Sbjct: 514 VIYALHAFDYEQIREFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAPEILYPSSDTEGT 573
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y F + + ++ KV A DAD G NA L+Y + + F I TG + +
Sbjct: 574 ALYEF-IPHSSDRGYLVTKVIAVDADSGHNAWLSYHLLQAQEPSVFTIGQSTGEIRLARG 632
Query: 1108 LDRETEDKYILTVVARDNG 1126
+ + V+ +DNG
Sbjct: 633 FQETDSSRQKVVVMVKDNG 651
Score = 54.4 bits (125), Expect = 2e-05
Identities = 57/208 (27%), Positives = 97/208 (46%), Gaps = 24/208 (11%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G + + +DRE I + + I+ + + I+D NDN P F + +
Sbjct: 81 ENGDLVITEKIDREALCGTEQQCILNLKAMIENPLQIFSIKVEIQDINDNAPSFPKNSLK 140
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV--VKF--- 848
I E++ G + A D D G N++ Y L + F + E T K+
Sbjct: 141 IVISESALPGVRFGLG---YAQDPDLGINSVQSYGL--STNDYFILGERTSSDGSKYPEL 195
Query: 849 -IGDSLDREKKIMYKLSLVARDTG-GLSSEAELI-IMIGDENDNKPEFNQIEENSKVRIH 905
+ SLDRE++ +LSL A D G + + LI I++ D NDN P F+Q +N +V I+
Sbjct: 196 VLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDANDNHPVFSQ--DNYQVNIY 253
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQ 933
N F++++++ A D+D+
Sbjct: 254 ENVANN----FSVLQIQ-----ATDIDE 272
Score = 51.6 bits (118), Expect = 2e-04
Identities = 83/368 (22%), Positives = 149/368 (40%), Gaps = 51/368 (13%)
Query: 8 LNLQPVDREEDA-----HLFTYRDLNRTHVSVILAQSIDSLVDSDSPQNVVK-FRLGCDF 61
L +Q D +E A + FT+ N H+ I +Q+ D V K + L +
Sbjct: 263 LQIQATDIDEGANGQITYSFTHIPENALHIFSIDSQTGQITKIGDLDYEVTKKYTLTVEA 322
Query: 62 DEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI 121
+G +LV ++ V++ + D NDN P + TV E +P I +
Sbjct: 323 KDGGELV----------SHCKVSIQVIDANDNAPEIQINSFLGTVPEDSPPETVIAIIYV 372
Query: 122 API--GPSLTIPLTVPRGL---------TIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDG 170
+ G + + +P L + +K + D+ T S+ + SI + D G
Sbjct: 373 HDLDSGENGEVVCQIPENLPFQLITLTESYYKLVTLSRMDRERT--SEYNISITA-KDKG 429
Query: 171 HFALESSHKPVLLLRKVLD-YDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGA 229
+L S + L V D +K + + + IL ++A+D D+
Sbjct: 430 TPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPGMSILH---VNALDFDINDNG 486
Query: 230 TLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNP 284
+ Y +IS + + S++S G ++ D + Q F QV A+ +P
Sbjct: 487 FITYSVISTAIQNIPISSHVSINSATGVIYALHAFDYE-----QIREFQFQVMATDNGSP 541
Query: 285 LKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENLPN----GFSVLQVMATDKDQGE 337
++ + + + ++D NDN PE D ++ E +P+ G+ V +V+A D D G
Sbjct: 542 SLSSNSTIRVCIIDKNDNAPEILYPSSDTEGTALYEFIPHSSDRGYLVTKVIAVDADSGH 601
Query: 338 NGEFTYQL 345
N +Y L
Sbjct: 602 NAWLSYHL 609
Score = 50.0 bits (114), Expect = 5e-04
Identities = 48/166 (28%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
++ G I LD E Y +TV A+ ++S +V+I + D NDN P + ++
Sbjct: 297 SQTGQITKIGDLDYEVTKKYTLTVEAKDGGELVSHC---KVSIQVIDANDNAPEIQINSF 353
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
G + E+S T I II D D G N + + E + K + S
Sbjct: 354 LGTVPEDSPPETVIA---IIYVHDLDSGENGEVVCQI-PENLPFQLITLTESYYKLVTLS 409
Query: 853 -LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+DRE+ Y +S+ A+D G LSS + + + D NDN P F +
Sbjct: 410 RMDRERTSEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPVFEK 455
Score = 49.6 bits (113), Expect = 6e-04
Identities = 60/236 (25%), Positives = 100/236 (42%), Gaps = 11/236 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + V L D NDN PVF ++ Y + N + G I V A+D D+ NG + Y
Sbjct: 433 LSSLKTIRVALTDVNDNIPVFEKTH-YVTYVPENNQPGMSILHVNALDFDINDNGFITYS 491
Query: 499 LQRTS--NLTITSPFKINPNTGTVSVAESPILEG-RHALF-VEASDQPANPSERRYSLAV 554
+ T+ N+ I+S IN TG + + E R F V A+D + ++ V
Sbjct: 492 VISTAIQNIPISSHVSINSATGVIYALHAFDYEQIREFQFQVMATDNGSPSLSSNSTIRV 551
Query: 555 VTIEVTRGTKGNKPDIPDFMG-APYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
I+ D G A YEF + + G V ++ DA ++ +SY LL
Sbjct: 552 CIIDKNDNAPEILYPSSDTEGTALYEF-IPHSSDRGYLVTKVIAVDADSGHNAWLSYHLL 610
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
E V F + + +G I + + V +++N ++ T++++
Sbjct: 611 QAQEPSV-FTIGQSTGEIRLARGFQETDSSRQKV-VVMVKDNGEPTLSATVTLNLI 664
Score = 48.8 bits (111), Expect = 0.001
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 13/199 (6%)
Query: 964 GQIRYEFNSEVY-IPPSKLSADALEVKRYFVINERHGHVIVARSLPPES------EFRLN 1016
G I +FN +V + L + + K+Y +N +G +++ + E+ + LN
Sbjct: 47 GNIANDFNLDVKELSLRNLHIASHDKKQYVNVNLENGDLVITEKIDREALCGTEQQCILN 106
Query: 1017 ISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
+ A+ L S++V ++D+ND+ P F K + E+ G A D D G
Sbjct: 107 LKAMIENPLQI-FSIKVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGI 165
Query: 1077 NANLTYFIQPSDTDLPFEISPLTG----VLSVNGELDRETEDKYILTVVARDNGXXXXXX 1132
N+ +Y + +D + E + G L + LDRE + L++ A D G
Sbjct: 166 NSVQSYGLSTNDYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGG-RPMKT 224
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D NDN P F
Sbjct: 225 GTTLIRIVVYDANDNHPVF 243
Score = 48.0 bits (109), Expect = 0.002
Identities = 47/170 (27%), Positives = 80/170 (47%), Gaps = 10/170 (5%)
Query: 230 TLRYELISGNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+LR I+ +D+K + +++ NG L + +++D +A + +L ++A + NPL+
Sbjct: 61 SLRNLHIASHDKKQYVNVNLENGDLVITEKIDREALCGTEQQC-ILNLKA-MIENPLQIF 118
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
+VEI+ D+NDN P F + I I E+ G A D D G N +Y L
Sbjct: 119 SIKVEIQ--DINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTN 176
Query: 349 K----GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G + S + + + LDRE SS+ + + A + P GT
Sbjct: 177 DYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGT 226
>UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
SCAF14742, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 891
Score = 97.1 bits (231), Expect = 3e-18
Identities = 137/573 (23%), Positives = 226/573 (39%), Gaps = 70/573 (12%)
Query: 812 IKATDADEGTNALFMYTLFGEG---KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
++A DAD G N Y+ + + +D TG++ ++ +DRE++ K + AR
Sbjct: 333 VRANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGII-YVKGQVDREEENFLKFFVAAR 391
Query: 869 DTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFA 928
D G +S+ +++ D IE I T NG A
Sbjct: 392 DRGP-NSKTSKVLVTITVKDQNDNSPSIEIRG---IGLVTHRNGVAN------------- 434
Query: 929 LDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEV 988
I E++P+GT + + D D G N + +V S + +
Sbjct: 435 -----------ISEDMPVGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESSNDR 483
Query: 989 KRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK 1046
KR + + ++R+ I A+D GN L+ ++V V DVND+ P+F
Sbjct: 484 KRKYFLQ-----TTTLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFS 538
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVN 1105
+ E Y + V ATDAD G NA LTY I +P+ +L FE+ +G + V
Sbjct: 539 PPLLKVDFAEGNYPGDKVLDVLATDADSGSNAELTYSISEPAALEL-FEVDANSGEVRVR 597
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEA 1165
L+RE + Y V A D G DVNDN PKF L ++
Sbjct: 598 AVLNREQREHYRFHVAAADKG-VPGKTGTATVEITVLDVNDNDPKFM----LDDYSFSVN 652
Query: 1166 DELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQ 1225
+ ++ N V ++ V ENA + V N I NG G IL S+ + ++
Sbjct: 653 ENMAPLN--PVGVVTVTDGDKGENARVTLLVEP--DNGKFVIQNGTGTILSSISFDREKE 708
Query: 1226 ----------NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
+ G P +S + + V D D KP S + L + + V
Sbjct: 709 STYTFRLKAVDAGDPPRTSYVAVTINVLDENDNAPYVTKP-SNSTFTHLLPDTPPDTRVA 767
Query: 1276 LVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVR- 1334
+V + N ++ Y + N + F I P +G + L + + + ++VR
Sbjct: 768 VVEAEDIDSGLNAELVYTLAGGNPFGL---FRIAPGSGEITLAQKLAGSHRGLHRLVVRV 824
Query: 1335 AERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV 1367
++R K R +++ V TKY+ ++
Sbjct: 825 SDRGKPPRHTTALVH-----VFVNETKYNTSLI 852
Score = 85.0 bits (201), Expect = 1e-14
Identities = 122/445 (27%), Positives = 181/445 (40%), Gaps = 47/445 (10%)
Query: 471 SNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG 530
SN + V +V+A D D G NG + Y + S+ T+ +I+ TG + V E
Sbjct: 322 SNRRRRLVASEVRANDADTGINGEIDYSFHQASD-TVQRLLRIDRFTGIIYVKGQVDREE 380
Query: 531 RHAL--FVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW------V 582
+ L FV A D+ N + S +VTI V + N P I + G +
Sbjct: 381 ENFLKFFVAARDRGPNS---KTSKVLVTITV-KDQNDNSPSI-EIRGIGLVTHRNGVANI 435
Query: 583 GSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAV--------EERSGVITVVD 633
++ +GT V ++V+D E +N V ++ G VPF + + +
Sbjct: 436 SEDMPVGTPVALVQVSDRDEGENAVVTCVVAG---DVPFQLRPASESSNDRKRKYFLQTT 492
Query: 634 DLSRYNRPM-YDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHV--- 688
L Y R Y E VA+ N LS V V DVND + SP + V
Sbjct: 493 TLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIF-----SPPLLKVDFA 547
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
+ N G + + T+ S + + I+ + A G + + L+RE+
Sbjct: 548 EGNYPGDKVLDVLATDADS---GSNAELTYSISEPAALELFEVDANSGEVRVRAVLNREQ 604
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
R+ YR V A +KGV G V I + D NDN P F Y + EN +
Sbjct: 605 REHYRFHVAAA-DKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENM---APLNP 660
Query: 809 DNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVAR 868
++ TD D+G NA + L F + TG + S DREK+ Y L A
Sbjct: 661 VGVVTVTDGDKGENAR-VTLLVEPDNGKFVIQNGTGTI-LSSISFDREKESTYTFRLKAV 718
Query: 869 DTGG--LSSEAELIIMIGDENDNKP 891
D G +S + I + DENDN P
Sbjct: 719 DAGDPPRTSYVAVTINVLDENDNAP 743
Score = 76.6 bits (180), Expect = 5e-12
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G A L Y + +LF +D+ +G + + L+ + Q + V A+
Sbjct: 561 ATDADSGSNAELTYSISEPAALELFEVDANSGEVRVRAVLNRE-----QREHYRFHVAAA 615
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P KT A VEI +LD+NDN P+F +D Y+ S+ EN+ V V TD D+GEN
Sbjct: 616 DKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENA 675
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
T ++ G F I +G T+ + DRE S+ ++ A
Sbjct: 676 RVTLLVEPDNGKFVIQNGTG--TILSSISFDREKESTYTFRLKA 717
Score = 70.1 bits (164), Expect = 4e-10
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 8/143 (5%)
Query: 254 FLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
FL+ LD E + + +++ A NP ++ +++++ D+NDN+P F +
Sbjct: 488 FLQTTTLLDYE---RVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKV 544
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG--AFSIDPRSGWLTVRNQTVLDR 371
E G VL V+ATD D G N E TY + +P F +D SG VR + VL+R
Sbjct: 545 DFAEGNYPGDKVLDVLATDADSGSNAELTYSISEPAALELFEVDANSG--EVRVRAVLNR 602
Query: 372 EAHSSLRMKVYAKETN-PSVVGT 393
E R V A + P GT
Sbjct: 603 EQREHYRFHVAAADKGVPGKTGT 625
Score = 68.9 bits (161), Expect = 1e-09
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 24/209 (11%)
Query: 727 TDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
T ++ I + + PL +K + I + KG+ SG + + I + D NDN P
Sbjct: 54 TTEVPIDRETLRDCRNPLAGDKCFLEFEVSITDMVKGLGSGPRLIEGRIEVLDINDNTPQ 113
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG--EGKEMF------D 838
F I EN+++G + I ATD D G N + YTL + ++F D
Sbjct: 114 FSSPILTLSIPENTQVGA---LFAIPMATDRDAGANGVAEYTLTAGPDADQLFSLQVAVD 170
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQI 896
DE + +G +LDREKK Y L++ D G +S A L + + D+NDN+P+F
Sbjct: 171 SDEKVPQLVVMG-NLDREKKDSYDLNIRVVDGGRPARASSALLRVSVTDQNDNQPKFE-- 227
Query: 897 EENSKVRIHRETKL--NGTAGFTIIEVKP 923
R H E +L N G+++++ +P
Sbjct: 228 ------RSHYEAELTENSPQGYSVLQPRP 250
Score = 67.3 bits (157), Expect = 3e-09
Identities = 48/153 (31%), Positives = 82/153 (53%), Gaps = 8/153 (5%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LD E+ YR+ ++A + G + + + + + D NDN P+F + E + G
Sbjct: 495 LDYERVKDYRIEIVA-VDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPG 553
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYK 862
++ +D + ATDAD G+NA Y++ E+F+VD N+G V+ + L+RE++ Y+
Sbjct: 554 DKV-LD--VLATDADSGSNAELTYSISEPAALELFEVDANSGEVR-VRAVLNREQREHYR 609
Query: 863 LSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ A D G G + A + I + D NDN P+F
Sbjct: 610 FHVAAADKGVPGKTGTATVEITVLDVNDNDPKF 642
Score = 64.9 bits (151), Expect = 2e-08
Identities = 118/478 (24%), Positives = 195/478 (40%), Gaps = 80/478 (16%)
Query: 952 KLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES 1011
++ A D D+G+NG+I Y F+ ++D V+R I+ G + V + E
Sbjct: 332 EVRANDADTGINGEIDYSFHQ---------ASDT--VQRLLRIDRFTGIIYVKGQVDREE 380
Query: 1012 E--FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFK------KTWYN--FNVEEAQY 1059
E + ++A D G + + V + VKD ND+ P + T N N+ E
Sbjct: 381 ENFLKFFVAARDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMP 440
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---------VLSVNGELDR 1110
+ V +D D G+NA +T + D+PF++ P + L LD
Sbjct: 441 VGTPVALVQVSDRDEGENAVVTCVVA---GDVPFQLRPASESSNDRKRKYFLQTTTLLDY 497
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E Y + +VA D+G DVNDN P F LL+ E N
Sbjct: 498 ERVKDYRIEIVAVDSG-NPALSSTNFLKVQVTDVNDNIPIF--SPPLLKVDFAE----GN 550
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLI----LYSLPQRKNQQ- 1225
+ + V+ + A NA + ++++ A + + +G + + + QR++ +
Sbjct: 551 YPGDKVLDVLATDADSGSNAELTYSISEPAALELFEVDANSGEVRVRAVLNREQREHYRF 610
Query: 1226 -----NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVS-L 1279
+ G+P + TA + +TV DV D + P F+ Y + EN+ AP+ V +
Sbjct: 611 HVAAADKGVPGKTGTATVEITVLDVND-----NDPKFMLDDYSFSVNENM-APLNPVGVV 664
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+T+ + R +L E D FVI GT+ S DRE + TY ++A
Sbjct: 665 TVTDGDKGENARVTLLVEPDNG---KFVIQNGTGTILSSISFDREKESTYTFRLKAVD-- 719
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN-GNRPLVTAIPTTAP 1396
+ + P Y V V + + D NDN+P T N +P T P
Sbjct: 720 -AGDPPRTSY--------------VAVTINVLDENDNAPYVTKPSNSTFTHLLPDTPP 762
Score = 64.1 bits (149), Expect = 3e-08
Identities = 81/311 (26%), Positives = 130/311 (41%), Gaps = 23/311 (7%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI--AP 123
++V + +G +S+ + V + DVNDN+PIF V E G+K L A
Sbjct: 506 EIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDAD 565
Query: 124 IGPS--LTIPLTVPRGLTIFK-DIRAFDRDKPNTPNSDV--HYSI-VSGNDDGHFALESS 177
G + LT ++ P L +F+ D + + N + HY V+ D G +
Sbjct: 566 SGSNAELTYSISEPAALELFEVDANSGEVRVRAVLNREQREHYRFHVAAADKG---VPGK 622
Query: 178 HKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI-DQDLGVGATLRYELI 236
+ VLD + D +F L + + L P + + D D G A R L+
Sbjct: 623 TGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENA--RVTLL 680
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
D F + + G++ D + E +T+ +++A +P +T+ V I +
Sbjct: 681 VEPDNGKFVIQNGTGTILSSISFDREKE-----STYTFRLKAVDAGDPPRTSYVAVTINV 735
Query: 297 LDLNDNLPEFEVDFYN--ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAF 352
LD NDN P + ++ + P V V A D D G N E Y L +P G F
Sbjct: 736 LDENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTLAGGNPFGLF 795
Query: 353 SIDPRSGWLTV 363
I P SG +T+
Sbjct: 796 RIAPGSGEITL 806
Score = 62.5 bits (145), Expect = 9e-08
Identities = 68/245 (27%), Positives = 102/245 (41%), Gaps = 17/245 (6%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
+F+ V+VT D NDN P+F P L + G + V A D D G N + Y +
Sbjct: 521 NFLKVQVT--DVNDNIPIFSPP-LLKVDFAEGNYPGDKVLDVLATDADSGSNAELTYSIS 577
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEGR-HALFVEASDQPANPSERRYSLAVVTIEV 559
+ L + F+++ N+G V V E R H F A+ P + T+E+
Sbjct: 578 EPAALEL---FEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGK----TGTATVEI 630
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T N D P FM Y F V N+ VG + V D + + LL + G
Sbjct: 631 T-VLDVNDND-PKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENARVTLLVEPDNG-K 687
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDF--EAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F ++ +G I R Y F +AV + S V T++V+D ND +
Sbjct: 688 FVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVA-VTINVLDENDNAPYVT 746
Query: 678 KGAHS 682
K ++S
Sbjct: 747 KPSNS 751
Score = 58.4 bits (135), Expect = 1e-06
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 9/148 (6%)
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEI--LFPEPIHAIDQDLGVGATLRYELISGNDR-K 242
+VLD + +F I+ + ++ LF P+ A D+D G Y L +G D +
Sbjct: 103 EVLDINDNTPQFSSPILTLSIPENTQVGALFAIPM-ATDRDAGANGVAEYTLTAGPDADQ 161
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNL---QANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
LFSL S EK L NL + +++ L ++ P + + A + + + D
Sbjct: 162 LFSLQVAVDSD--EKVPQLVVMGNLDREKKDSYDLNIRVVDGGRPARASSALLRVSVTDQ 219
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQ 327
NDN P+FE Y + EN P G+SVLQ
Sbjct: 220 NDNQPKFERSHYEAELTENSPQGYSVLQ 247
Score = 58.0 bits (134), Expect = 2e-06
Identities = 69/258 (26%), Positives = 107/258 (41%), Gaps = 20/258 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVNDERGVLL 677
F V+ SG + V L+R R Y F A + T ATV V+DVND +
Sbjct: 585 FEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGKTGT-ATVEITVLDVNDNDPKFM 643
Query: 678 KGAHSPIIFHVKENSAGA-AIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDG 736
+S F V EN A +G + T+ G+ N R + + D + G
Sbjct: 644 LDDYS---FSVNENMAPLNPVGVVTVTD-----GDKGENARVTLLVEPDNGKFVIQNGTG 695
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF- 795
TI + DREK Y + A + G VTI + DENDN P + F
Sbjct: 696 TILSSISFDREKESTYTFRLKA-VDAGDPPRTSYVAVTINVLDENDNAPYVTKPSNSTFT 754
Query: 796 -IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSL 853
++ ++ T + +++A D D G NA +YTL G +F + +G + + L
Sbjct: 755 HLLPDTPPDTRVA---VVEAEDIDSGLNAELVYTLAGGNPFGLFRIAPGSGEIT-LAQKL 810
Query: 854 DREKKIMYKLSLVARDTG 871
+ +++L + D G
Sbjct: 811 AGSHRGLHRLVVRVSDRG 828
Score = 56.8 bits (131), Expect = 4e-06
Identities = 51/175 (29%), Positives = 86/175 (49%), Gaps = 20/175 (11%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE------- 788
G I+ + +DRE+ + + V A ++G S VTI ++D+NDN P E
Sbjct: 368 GIIYVKGQVDREEENFLKFFVAAR-DRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLV 426
Query: 789 -HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-EMFDVDENTGVV 846
H I E+ +GT + + ++ +D DEG NA+ + G+ ++ E++
Sbjct: 427 THRNGVANISEDMPVGTPVAL---VQVSDRDEGENAVVTCVVAGDVPFQLRPASESSNDR 483
Query: 847 K---FIGDS--LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
K F+ + LD E+ Y++ +VA D+G LSS L + + D NDN P F+
Sbjct: 484 KRKYFLQTTTLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFS 538
Score = 55.2 bits (127), Expect = 1e-05
Identities = 51/200 (25%), Positives = 95/200 (47%), Gaps = 26/200 (13%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
L + A D D G+ + Y +D ++L +D G ++++ ++D + E+ L+
Sbjct: 328 LVASEVRANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQVDREEENFLK-- 385
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNI--------SIVENLPNG 322
F + + N+ KT++ V I + D NDN P E+ + +I E++P G
Sbjct: 386 -FFVAARDRGPNS--KTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMPVG 442
Query: 323 FSVLQVMATDKDQGEN--------GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAH 374
V V +D+D+GEN G+ +QL P S D + + ++ T+LD E
Sbjct: 443 TPVALVQVSDRDEGENAVVTCVVAGDVPFQL-RPASESSNDRKRKYF-LQTTTLLDYERV 500
Query: 375 SSLRMKVYAKET-NPSVVGT 393
R+++ A ++ NP++ T
Sbjct: 501 KDYRIEIVAVDSGNPALSST 520
Score = 52.4 bits (120), Expect = 9e-05
Identities = 95/342 (27%), Positives = 137/342 (40%), Gaps = 48/342 (14%)
Query: 1061 RRVLGKVDATDADFGQNANLTY-FIQPSDT-DLPFEISPLTGVLSVNGELDRETEDKYIL 1118
R V +V A DAD G N + Y F Q SDT I TG++ V G++DRE E+
Sbjct: 327 RLVASEVRANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQVDREEENFLKF 386
Query: 1119 TVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMM 1178
V ARD G D NDNSP E+ L H V
Sbjct: 387 FVAARDRG-PNSKTSKVLVTITVKDQNDNSPSI----EI------RGIGLVTHR-NGV-- 432
Query: 1179 IPVYKATIEENAPIGTTVAKVFANDTDFIGNG------NGLILYSLPQRKNQQNLGLPS- 1231
A I E+ P+GT VA V +D D N G + + L N
Sbjct: 433 -----ANISEDMPVGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESSNDRKRKY 487
Query: 1232 -LSSTAIL-MVTVADVPDEVEMSD--KPVFIS-RYYELEIEE-NVNAPV---ELVSLNLT 1282
L +T +L V D E+ D P S + ++++ + N N P+ L+ ++
Sbjct: 488 FLQTTTLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFA 547
Query: 1283 E-HYENFKMRYYILNEND--TDIRRTFVI-DPRNGTLYLVRSPDREVKDTYEVIVRAERQ 1338
E +Y K+ + + D ++ T+ I +P L+ V + EV+ VRA
Sbjct: 548 EGNYPGDKVLDVLATDADSGSNAELTYSISEPAALELFEVDANSGEVR------VRAVLN 601
Query: 1339 KYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+ RE A+ + G T V + + DVNDN PKF
Sbjct: 602 REQREHYRFHVAAADKGVPGKTG-TATVEITVLDVNDNDPKF 642
Score = 49.6 bits (113), Expect = 6e-04
Identities = 63/233 (27%), Positives = 96/233 (41%), Gaps = 18/233 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VE+T+LD NDN+P F+ + Y FS+ N +G V D D G+N V L N
Sbjct: 628 VEITVLDVNDNDPKFMLDD-YSFSVNENMAPLNPVGVVTVTDGDKGENARVTL-LVEPDN 685
Query: 505 LTITSPFKINPNTGTV--SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I TGT+ S++ E + ++A D P R S VTI V
Sbjct: 686 ----GKFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPP---RTSYVAVTINVL-D 737
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
N P + + + + + T V + D ++ Y L G G+ F
Sbjct: 738 ENDNAPYVTKPSNSTFTHLL-PDTPPDTRVAVVEAEDIDSGLNAELVYTLAGGNPFGL-F 795
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
+ SG IT+ L+ +R ++ V + + T A VHV VN+ +
Sbjct: 796 RIAPGSGEITLAQKLAGSHRGLHRL-VVRVSDRGKPPRHTTALVHVF-VNETK 846
Score = 48.4 bits (110), Expect = 0.002
Identities = 44/143 (30%), Positives = 68/143 (47%), Gaps = 10/143 (6%)
Query: 436 DEQLMSFVNVEVTLLDANDNNP-VFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
D S+V V + +LD NDN P V PSN + + T + V+A D D G N
Sbjct: 722 DPPRTSYVAVTINVLDENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAE 781
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSL 552
++Y L + + F+I P +G +++A+ + G H L V SD+ P R++
Sbjct: 782 LVYTLAGGNPFGL---FRIAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPP---RHTT 835
Query: 553 AVVTIEVTRGTKGNKPDIPDFMG 575
A+V + V TK N I +G
Sbjct: 836 ALVHVFVNE-TKYNTSLIEALVG 857
Score = 47.6 bits (108), Expect = 0.003
Identities = 24/52 (46%), Positives = 29/52 (55%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
IE+LD+NDN P+F +SI EN G MATD+D G NG Y L
Sbjct: 102 IEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTL 153
Score = 47.2 bits (107), Expect = 0.003
Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 8/130 (6%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS- 1087
I R+ V D+ND+ P F ++ E + ATD D G N Y +
Sbjct: 98 IEGRIEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTLTAGP 157
Query: 1088 DTDLPFEISPLTG------VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
D D F + L V G LDRE +D Y L + D G
Sbjct: 158 DADQLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVDGG-RPARASSALLRVSV 216
Query: 1142 XDVNDNSPKF 1151
D NDN PKF
Sbjct: 217 TDQNDNQPKF 226
Score = 45.2 bits (102), Expect = 0.014
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 13/150 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPII-FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
+ V+D+ND SPI+ + EN+ A+ I NG
Sbjct: 102 IEVLDINDNTPQF----SSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTLTAGP 157
Query: 723 QQDVTDDIAIAEDGT-----IFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIY 776
D + +A D + LDREK+D Y + + + + + + + + +V++
Sbjct: 158 DADQLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVDGGRPARASSALLRVSV- 216
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEI 806
D+NDN P FE + YE + ENS G +
Sbjct: 217 -TDQNDNQPKFERSHYEAELTENSPQGYSV 245
Score = 39.9 bits (89), Expect = 0.53
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN +G A D D+G NG Y + P +L+V +E+
Sbjct: 123 IPENTQVGALFAIPMATDRDAGANGVAEYTLTA----GPDADQLFSLQVA--VDSDEKVP 176
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++V +L E + + LNI +DGG + +RV V D ND+ P F+++ Y +
Sbjct: 177 QLVVMGNLDREKKDSYDLNIRVVDGGRPARASSALLRVSVTDQNDNQPKFERSHYEAELT 236
Query: 1056 E 1056
E
Sbjct: 237 E 237
Score = 38.3 bits (85), Expect = 1.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ +LD NDN P F S + S+ N +VG + A D D G NG+ Y L
Sbjct: 102 IEVLDINDNTPQF-SSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTL 153
>UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28;
Tetrapoda|Rep: Cadherin-11 precursor - Mus musculus
(Mouse)
Length = 796
Score = 97.1 bits (231), Expect = 3e-18
Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 5/189 (2%)
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGI 770
+G GN++++++ + T + + G I K LDRE+R Y + A
Sbjct: 83 SGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPP 142
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+ + ++D NDNPP F H Y + E S +GT + A D G +A +Y++
Sbjct: 143 SEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSIL 202
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDE 886
EG+ F V+ TG+++ ++DRE K Y + + A+D GGLS ++ I + D
Sbjct: 203 -EGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDV 261
Query: 887 NDNKPEFNQ 895
NDN P+F Q
Sbjct: 262 NDNPPKFPQ 270
Score = 92.3 bits (219), Expect = 9e-17
Identities = 85/287 (29%), Positives = 133/287 (46%), Gaps = 22/287 (7%)
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
VG++ + ++ Y +L G G F ++++SG I L R R Y A A+
Sbjct: 74 VGRLHSDIDSGDGNIKY-ILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVD 132
Query: 652 ENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSS- 707
+ N L + V V D+ND L H +V E S G ++ Q+ ++
Sbjct: 133 RDTNRPLEPPSEFIVKVQDINDNPPEFL---HEIYHANVPERSNVGTSVIQVTASDADDP 189
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVIS 766
YGN V ++ Q + + A+ G I T P +DRE ++ Y + + A+ G +
Sbjct: 190 TYGNSAKLVYSILEGQPYFSVE---AQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMG 246
Query: 767 G-AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
G +G +VTI + D NDNPP F + Y+ + E + G E+ +KA D D G N L
Sbjct: 247 GLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEV---GRVKAKDPDIGENGLV 303
Query: 826 MYTLF-GEGKEMF----DVDENTGVVKFIGDSLDREKKIMYKLSLVA 867
Y + G+G E+F D + GVVK + +D E K Y L + A
Sbjct: 304 TYNIVDGDGIELFEITTDYETQDGVVK-LKKPVDFETKRAYSLKIEA 349
Score = 77.0 bits (181), Expect = 4e-12
Identities = 105/417 (25%), Positives = 175/417 (41%), Gaps = 57/417 (13%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
FVI+++ G++ ++L E +++ L A+D L V V+D+ND+ P F
Sbjct: 101 FVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFL 160
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVL- 1102
Y+ NV E + +V A+DAD +G +A L Y I F + TG++
Sbjct: 161 HEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP--YFSVEAQTGIIR 218
Query: 1103 SVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ +DRE +++Y + + A+D G DVNDN PKF + +
Sbjct: 219 TALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFP--QSVYQMS 276
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA-----KVFANDTDFIGNGNGLILY 1216
EA E V + I EN + + ++F TD+ +G++
Sbjct: 277 VSEAAVPG----EEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDY-ETQDGVVKL 331
Query: 1217 SLP---QRKNQQNLGL--------PSLSSTAILMVTVADVPDEVEMSDK-PVFISRYYEL 1264
P + K +L + P S TV V VE +D+ P+F++ Y
Sbjct: 332 KKPVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVT-VKISVEDADEPPMFLAPSYIH 390
Query: 1265 EIEENVNAPVELVSLNLTE-HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
E++EN A + ++ + N +RY I + TD+ R F I+P +G + + DR
Sbjct: 391 EVQENAAAGTVVGRVHAKDPDAANSPIRYSI--DRHTDLDRFFTINPEDGFIKTTKPLDR 448
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
E + V A ++ + V V +R+ DVNDN+PKF
Sbjct: 449 EETAWLNISV-----------------FAAEIHNRHQETKVPVAIRVLDVNDNAPKF 488
Score = 77.0 bits (181), Expect = 4e-12
Identities = 63/240 (26%), Positives = 102/240 (42%), Gaps = 11/240 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V +TL D NDN P F P ++Y+ S+ A G +G+VKA DPD+G+NG+V Y+
Sbjct: 248 LSGTTKVTITLTDVNDNPPKF-PQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYN 306
Query: 499 LQRTSNL---TITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLA 553
+ + IT+ ++ G V + + E + A L +EA++ +P
Sbjct: 307 IVDGDGIELFEITTDYE--TQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNGPF 364
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYDLLH 612
T+ V + + + P F+ Y V N GT VG++ D N + Y +
Sbjct: 365 KDTVTVKISVE-DADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDR 423
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVND 671
+ F + G I L R + A + N + + V+DVND
Sbjct: 424 HTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAIRVLDVND 483
Score = 71.7 bits (168), Expect = 1e-10
Identities = 114/455 (25%), Positives = 188/455 (41%), Gaps = 53/455 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
V + D NDN P F+ +Y ++ + VGT + +V A D P G + ++Y +
Sbjct: 147 VKVQDINDNPPEFL-HEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSI---- 201
Query: 504 NLTITSPFKINPNTGTVSVA----ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
L F + TG + A + E H + ++A D + VTI +
Sbjct: 202 -LEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVV-IQAKDMGGHMGGLS-GTTKVTITL 258
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEG 617
T N P P + Y+ V G VG+++ D E V+Y+++ G +G
Sbjct: 259 T-DVNDNPPKFPQSV---YQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDG--DG 312
Query: 618 VP-FAV----EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA------TVHV 666
+ F + E + GV+ + + + Y + A + + ++N TV +
Sbjct: 313 IELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKI 372
Query: 667 -VDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
V+ DE + L ++ I V+EN+A G +G++ + + +R+ I
Sbjct: 373 SVEDADEPPMFLAPSY---IHEVQENAAAGTVVGRVHAKDPDA----ANSPIRYSIDRHT 425
Query: 725 DVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
D+ I EDG I T KPLDRE+ ++V A + V I + D NDN
Sbjct: 426 DLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKV-PVAIRVLDVNDN 484
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNI-IKATDADEGTNA-LFMYTLFGE-----GKEM 836
P F A YEGFI E+ + + A D D+ N F+++L E +
Sbjct: 485 APKFA-APYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEIMHNPNFTV 543
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
D +NT V R+K+ Y L +V D G
Sbjct: 544 RDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGG 578
Score = 66.9 bits (156), Expect = 4e-09
Identities = 61/196 (31%), Positives = 94/196 (47%), Gaps = 27/196 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE +GT++I++ A D D G NS +KL LE + YF + + G
Sbjct: 168 VPERSNVGTSVIQVTASDADDPTYG------NS------AKLVYSILEGQPYFSVEAQTG 215
Query: 1000 HVIVARSLP-----PESEFRLNISALD-GGN---LNDNISVRVFVKDVNDHFPVFKKTWY 1050
I+ +LP + E+ + I A D GG+ L+ V + + DVND+ P F ++ Y
Sbjct: 216 --IIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVY 273
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS----PLTGVLSVNG 1106
+V EA +G+V A D D G+N +TY I D FEI+ GV+ +
Sbjct: 274 QMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKK 333
Query: 1107 ELDRETEDKYILTVVA 1122
+D ET+ Y L + A
Sbjct: 334 PVDFETKRAYSLKIEA 349
Score = 63.3 bits (147), Expect = 5e-08
Identities = 47/167 (28%), Positives = 81/167 (48%), Gaps = 9/167 (5%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D G G ++Y L +F +D +G++ K LD E Q T + Q
Sbjct: 80 DIDSGDG-NIKYILSGEGAGTIFVIDDKSGNIHATKTLD--REERAQY-TLMAQAVDRDT 135
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GEN 338
N PL+ + +++ D+NDN PEF + Y+ ++ E G SV+QV A+D D G +
Sbjct: 136 NRPLEPPSEFI-VKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNS 194
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ Y + + + FS++ ++G + +DREA + + AK+
Sbjct: 195 AKLVYSILEGQPYFSVEAQTGIIRTALPN-MDREAKEEYHVVIQAKD 240
Score = 59.7 bits (138), Expect = 6e-07
Identities = 78/323 (24%), Positives = 131/323 (40%), Gaps = 29/323 (8%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-----GPSLTIPLTVPRGLT 139
V ++D+NDN P FL YH V E + G + G S + ++ G
Sbjct: 147 VKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP 206
Query: 140 IFKDIRAFDRDKPNTPNSD------VHYSIVSGNDDGHFA-LESSHKPVLLLRKVLDYDA 192
F + PN D H I + + GH L + K + L V D
Sbjct: 207 YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPP 266
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL----DS 248
+ + S + E + + A D D+G + Y ++ G+ +LF + ++
Sbjct: 267 KFPQSVYQMSVSEAAVPGEEV--GRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYET 324
Query: 249 VNGSLFLEKELDLDAE--HNLQANTFVLQVQASQLNN-PLKTAQARVEIELLDLNDNLPE 305
+G + L+K +D + + ++L+ + + ++N P K V+I + D D P
Sbjct: 325 QDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNGPFKDT-VTVKISVEDA-DEPPM 382
Query: 306 FEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKGAFSIDPRSGWLT 362
F Y + EN G V +V A D D N Y +D D F+I+P G+
Sbjct: 383 FLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDGF-- 439
Query: 363 VRNQTVLDREAHSSLRMKVYAKE 385
++ LDRE + L + V+A E
Sbjct: 440 IKTTKPLDREETAWLNISVFAAE 462
Score = 56.8 bits (131), Expect = 4e-06
Identities = 50/160 (31%), Positives = 73/160 (45%), Gaps = 8/160 (5%)
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNAN 1079
+ G D ++V++ V+D D P+F Y V+E V+G+V A D D N+
Sbjct: 359 ISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSP 416
Query: 1080 LTYFI-QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXX 1138
+ Y I + +D D F I+P G + LDRE ++V A +
Sbjct: 417 IRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEI-HNRHQETKVPVA 475
Query: 1139 XXXXDVNDNSPKFYAFDE--LLEWKHPEADELSNHNFESV 1176
DVNDN+PKF A E + E HP+A LSN +V
Sbjct: 476 IRVLDVNDNAPKFAAPYEGFICESDHPKA--LSNQPIVTV 513
Score = 47.2 bits (107), Expect = 0.003
Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 28/208 (13%)
Query: 934 LGPLFL--IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRY 991
L P ++ + EN GT + +++A D D+ N IRY + ++ R+
Sbjct: 384 LAPSYIHEVQENAAAGTVVGRVHAKDPDAA-NSPIRYSIDRHT------------DLDRF 430
Query: 992 FVINERHGHVIVARSLPPESEFRLNISA----LDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F IN G + + L E LNIS + + + V + V DVND+ P F
Sbjct: 431 FTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFAA 490
Query: 1048 TWYNFNVEEAQ---YTRRVLGKVDATDADFGQNANLTYFIQPSDT--DLPFEISP----L 1098
+ F E + + + V A D D N F P + + F +
Sbjct: 491 PYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEIMHNPNFTVRDNRDNT 550
Query: 1099 TGVLSVNGELDRETEDKYILTVVARDNG 1126
GV + G R+ +D Y+L +V D G
Sbjct: 551 AGVYARRGGFSRQKQDFYLLPIVISDGG 578
Score = 46.8 bits (106), Expect = 0.005
Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 11/133 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+HA D D + +RY + D + F+++ +G F++ LD E N + V
Sbjct: 405 VHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDG--FIKTTKPLDREETAWLN---ISV 458
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFS---VLQVMATDK 333
A++++N + + V I +LD+NDN P+F + + P S ++ V A D+
Sbjct: 459 FAAEIHNRHQETKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTVSADDQ 518
Query: 334 DQGENG-EFTYQL 345
D NG F + L
Sbjct: 519 DDTANGPRFIFSL 531
>UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadherin
gamma A2 precursor (PCDH-gamma-A2) isoform 4; n=3;
Catarrhini|Rep: PREDICTED: similar to Protocadherin gamma
A2 precursor (PCDH-gamma-A2) isoform 4 - Pan troglodytes
Length = 878
Score = 96.7 bits (230), Expect = 4e-18
Identities = 120/418 (28%), Positives = 186/418 (44%), Gaps = 50/418 (11%)
Query: 741 QKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
++ LDRE+ V+ + ++A + V+SG ++ + + D NDN PVF Y I EN
Sbjct: 197 ERALDREEEAVHHLVLVASDGGDPVLSGTS--RICVKVLDANDNAPVFTQPEYRISIPEN 254
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGVVKFIGDSLDRE 856
+ +GT I + ATDADEG A +Y L GE E+F++ +G + I D LD E
Sbjct: 255 TPVGTRIL---TVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKD-LDYE 310
Query: 857 KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT-AG 915
+++ + A+D GL + A++I+ + D NDN PEF S V E L GT G
Sbjct: 311 DATFHEIDIEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSV---SEDSLPGTIIG 367
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIP--IGTTIIKLNALDLDSGLNGQIRYEFNSE 973
+ + + A L PEN+P + ++ L L+ + +N
Sbjct: 368 LFNVHDRDSGQNAFTTCSL------PENLPFKLEKSVDNYYRLVTTRALDREQFSFYNIT 421
Query: 974 VYIPPS---KLSADALEVKRYFVINER---HGHVIVARSLP---PESEFRLNISALDGGN 1024
+ LS DA + + IN+ + +P P +++A D +
Sbjct: 422 LTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDS 481
Query: 1025 LNDNISV-------RVFVKDVNDH-----FPVFKKTWYNFNVEEAQYTRR---VLGKVDA 1069
NDN V V V D ND+ +P F T + VE A + ++ KV A
Sbjct: 482 -NDNAHVTYSFVEDTVLVLDQNDNPPEILYPAF-PTDGSTGVELAPRSAEPGYLVTKVVA 539
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTG-VLSVNGELDRETEDKYILTVVARDNG 1126
D D GQNA L+Y + + F + TG V + LDR+ K L V +D+G
Sbjct: 540 VDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDAL-KQSLVVAVQDHG 596
Score = 76.6 bits (180), Expect = 5e-12
Identities = 65/217 (29%), Positives = 89/217 (41%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN P+GT I+ + A D D G Q+ VY L E F + G
Sbjct: 251 IPENTPVGTRILTVTATDADEGYYAQV-------VYF----LEKSPGETSEVFELKSTSG 299
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ + + L E ++I A DG L V V V DVND+ P F T +V E
Sbjct: 300 ELTIIKDLDYEDATFHEIDIEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSED 359
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
++G + D D GQNA T + +LPF++ L LDRE
Sbjct: 360 SLPGTIIGLFNVHDRDSGQNAFTTCSL---PENLPFKLEKSVDNYYRLVTTRALDREQFS 416
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y +T+ A+D G D+NDN+P F
Sbjct: 417 FYNITLTAKDGG-NPSLSTDAHILLQVADINDNAPAF 452
Score = 76.2 bits (179), Expect = 7e-12
Identities = 96/415 (23%), Positives = 164/415 (39%), Gaps = 30/415 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E ++ +VEV + D NDN P F L E + G I A D D+G+N +
Sbjct: 111 EDKLTIYSVEVEITDINDNAPRFGVEEL-ELKISETTTPGFRIPLKNAHDADVGENALQK 169
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + ++ + N V E + E H L + ASD +
Sbjct: 170 YALNPNDHFSLDVRSGADGNKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRIC 229
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
V ++ + P F Y + N +GT + + DA E V Y L
Sbjct: 230 VKVLDAN-------DNAPVFTQPEYRISIPENTPVGTRILTVTATDADEGYYAQVVYFLE 282
Query: 612 HGY-EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
E F ++ SG +T++ DL + ++ + A Q+ L V V+DVN
Sbjct: 283 KSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEA-QDGPGLLTRAKVIVTVLDVN 341
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN-QQDVTDD 729
D + + V E+S I +F+ ++ +G F + +++
Sbjct: 342 DNAPEFYMTSATS---SVSEDSLPGTIIGLFN-----VHDRDSGQNAFTTCSLPENLPFK 393
Query: 730 IAIAEDG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ + D + T + LDRE+ Y +T+ A+ + G S + + + + D NDN P F
Sbjct: 394 LEKSVDNYYRLVTTRALDREQFSFYNITLTAK-DGGNPSLSTDAHILLQVADINDNAPAF 452
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
+Y +I EN+ G + + A D D NA Y+ + + D ++N
Sbjct: 453 SRTSYSTYIPENNPRGASVFS---VTAHDPDSNDNAHVTYSFVEDTVLVLDQNDN 504
Score = 74.5 bits (175), Expect = 2e-11
Identities = 101/368 (27%), Positives = 158/368 (42%), Gaps = 46/368 (12%)
Query: 218 IHAIDQDLGVGATLRY--ELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G A + Y E G ++F L S +G L + K+LD + A +
Sbjct: 264 VTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYE-----DATFHEID 318
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
++A + P +A+V + +LD+NDN PEF + S+ E+ G + D+D
Sbjct: 319 IEAQ--DGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDS 376
Query: 336 GENGEFTYQLDDP---KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVV 391
G+N T L + K S+D +T R LDRE S + + AK+ NPS+
Sbjct: 377 GQNAFTTCSLPENLPFKLEKSVDNYYRLVTTR---ALDREQFSFYNITLTAKDGGNPSLS 433
Query: 392 GTFADSQRIAKWRRQPLETNAP-LEKTTY--VFPDK--VGTKTENIEYYDEQ-------L 439
++A + NAP +T+Y P+ G ++ +D
Sbjct: 434 TDAHILLQVA-----DINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488
Query: 440 MSFVNVEVTLLDANDNNP-VFVP------SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
SFV V +LD NDN P + P S E + +S A+ G ++ KV AVD D GQN
Sbjct: 489 YSFVEDTVLVLDQNDNPPEILYPAFPTDGSTGVELAPRS-AEPGYLVTKVVAVDRDSGQN 547
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRY 550
+ Y L + S + F + +TG V A + + + +L V D P
Sbjct: 548 AWLSYHLLKASEPGL---FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 604
Query: 551 SLAVVTIE 558
+L V +
Sbjct: 605 TLTVAVAD 612
Score = 74.1 bits (174), Expect = 3e-11
Identities = 92/342 (26%), Positives = 141/342 (41%), Gaps = 31/342 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E G I NA D D G N +Y N P S D R ++
Sbjct: 142 ISETTTPGFRIPLKNAHDADVGENALQKYALN-----PNDHFSLDV----RSGADGNKYP 192
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ R+L E E L + A DGG+ L+ + V V D ND+ PVF + Y ++
Sbjct: 193 ELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIP 252
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQ--PSDTDLPFEISPLTGVLSVNGELDRETE 1113
E + V ATDAD G A + YF++ P +T FE+ +G L++ +LD E
Sbjct: 253 ENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDA 312
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY---AFDELLEWKHP-EADELS 1169
+ + + A+D DVNDN+P+FY A + E P L
Sbjct: 313 TFHEIDIEAQDG---PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLF 369
Query: 1170 NHNFESVMMIPVYKATIEENAP--IGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
N + ++ EN P + +V + T + Y++ ++
Sbjct: 370 NVHDRDSGQNAFTTCSLPENLPFKLEKSVDNYYRLVTTRALDREQFSFYNI--TLTAKDG 427
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
G PSLS+ A +++ VAD+ D + P F Y I EN
Sbjct: 428 GNPSLSTDAHILLQVADIND-----NAPAFSRTSYSTYIPEN 464
Score = 70.1 bits (164), Expect = 4e-10
Identities = 57/168 (33%), Positives = 76/168 (45%), Gaps = 9/168 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G++ T +DRE+ + FN + IY V + I D NDN P F E
Sbjct: 82 GSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFGVEELELK 141
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKFIGD 851
I E + G I + N A DAD G NAL Y L DV D N +
Sbjct: 142 ISETTTPGFRIPLKN---AHDADVGENALQKYALNPNDHFSLDVRSGADGNKYPELVLER 198
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIE 897
+LDRE++ ++ L LVA D G LS + + + + D NDN P F Q E
Sbjct: 199 ALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPE 246
Score = 69.3 bits (162), Expect = 8e-10
Identities = 52/152 (34%), Positives = 78/152 (51%), Gaps = 11/152 (7%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLD---SVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+A D D+G A +Y L + ND FSLD +G+ + E L+ + +A ++
Sbjct: 156 NAHDADVGENALQKYAL-NPNDH--FSLDVRSGADGNKYPELVLERALDREEEAVHHLVL 212
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V AS +P+ + +R+ +++LD NDN P F Y ISI EN P G +L V ATD D+
Sbjct: 213 V-ASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTPVGTRILTVTATDADE 271
Query: 336 GENGEFTYQLDDPKG----AFSIDPRSGWLTV 363
G + Y L+ G F + SG LT+
Sbjct: 272 GYYAQVVYFLEKSPGETSEVFELKSTSGELTI 303
Score = 62.5 bits (145), Expect = 9e-08
Identities = 65/268 (24%), Positives = 114/268 (42%), Gaps = 21/268 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L + V +LDANDN PVF Y S+ N VGT I V A D D G V
Sbjct: 219 DPVLSGTSRICVKVLDANDNAPVFTQPE-YRISIPENTPVGTRILTVTATDADEGYYAQV 277
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLA 553
+Y L+++ T + F++ +G +++ + E H + +EA D P + + +
Sbjct: 278 VYFLEKSPGET-SEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPGLLTRAKVIVT 336
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
V+ + + P+F V + GT +G V+D + ++
Sbjct: 337 VLDV---------NDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDR-DSGQNAFTTC-S 385
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL--QENANLSIVTNATV--HVVDV 669
E +PF +E+ + +R + F + L ++ N S+ T+A + V D+
Sbjct: 386 LPENLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADI 445
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAI 697
ND + ++S I + N GA++
Sbjct: 446 NDNAPAFSRTSYSTYI--PENNPRGASV 471
Score = 61.7 bits (143), Expect = 2e-07
Identities = 62/244 (25%), Positives = 108/244 (44%), Gaps = 15/244 (6%)
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTG 714
LS + V V+D ND V + + + EN+ G I + T+ Y
Sbjct: 222 LSGTSRICVKVLDANDNAPVFTQPEYR---ISIPENTPVGTRILTVTATDADEGYYAQV- 277
Query: 715 NVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
V FL + + ++ + + G + K LD E + + + A+ G+++ A +V
Sbjct: 278 -VYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPGLLTRA---KV 333
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
+ + D NDN P F + + E+S GT I + N+ D D G NA +L
Sbjct: 334 IVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNV---HDRDSGQNAFTTCSLPENL 390
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
+ + +LDRE+ Y ++L A+D G LS++A +++ + D NDN P
Sbjct: 391 PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450
Query: 892 EFNQ 895
F++
Sbjct: 451 AFSR 454
Score = 58.4 bits (135), Expect = 1e-06
Identities = 108/442 (24%), Positives = 172/442 (38%), Gaps = 71/442 (16%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNI---SVRVFVKDVNDHFPVFK 1046
F +N R G ++ A + E + L N L D + SV V + D+ND+ P F
Sbjct: 75 FALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPRFG 134
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV----- 1101
+ E + +A DAD G+NA Y + P+D F + +G
Sbjct: 135 VEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDH---FSLDVRSGADGNKY 191
Query: 1102 --LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
L + LDRE E + L +VA D G D NDN+P
Sbjct: 192 PELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVL-DANDNAP---------- 240
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLP 1219
V P Y+ +I EN P+GT + V A D D ++Y L
Sbjct: 241 ----------------VFTQPEYRISIPENTPVGTRILTVTATDAD--EGYYAQVVYFLE 282
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDE--------VEMSDKPVFISRYYELE--IEEN 1269
+ + + + L ST+ + + D+ E +E D P ++R + ++ N
Sbjct: 283 KSPGETS-EVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPGLLTRAKVIVTVLDVN 341
Query: 1270 VNAPVELVSLNLTEHYENFKMRYYIL---NENDTDIRR---TFVIDPRNGTLYLVRSPDR 1323
NAP E + T + I+ N +D D + T P N L +S D
Sbjct: 342 DNAP-EFYMTSATSSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPENLPFKLEKSVDN 400
Query: 1324 EVKDTYEVIVRA-ERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
+ V RA +R+++S + I A+D D +++++ D+NDN+P F+
Sbjct: 401 YYR---LVTTRALDREQFSF---YNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSR 454
Query: 1383 GNRPLVTAIPTTAPFGYQVMQL 1404
+ T IP P G V +
Sbjct: 455 TS--YSTYIPENNPRGASVFSV 474
Score = 56.0 bits (129), Expect = 7e-06
Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 5/125 (4%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
++S +LF+L+ +GSL +D + L A + + + L T + VE+
Sbjct: 66 IVSRGRSQLFALNPRSGSLVTANRIDRE---ELCAQSAPCLLNFNILLEDKLTIYS-VEV 121
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
E+ D+NDN P F V+ + I E GF + A D D GEN Y L +P FS+
Sbjct: 122 EITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYAL-NPNDHFSL 180
Query: 355 DPRSG 359
D RSG
Sbjct: 181 DVRSG 185
Score = 36.3 bits (80), Expect = 6.5
Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 17/140 (12%)
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK--------MDNIIKATDADEGTNALF 825
T+ + D+NDNPP Y F + S G E+ + + A D D G NA
Sbjct: 495 TVLVLDQNDNPP---EILYPAFPTDGS-TGVELAPRSAEPGYLVTKVVAVDRDSGQNAWL 550
Query: 826 MYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIM 882
Y L + +F V +TG V+ LDR+ + L + +D G LS+ L +
Sbjct: 551 SYHLLKASEPGLFSVGLHTGEVRTARALLDRD-ALKQSLVVAVQDHGQPPLSATVTLTVA 609
Query: 883 IGDE-NDNKPEFNQIEENSK 901
+ D D + +E ++K
Sbjct: 610 VADRIPDILADLGSLEPSAK 629
>UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069ECF7 UniRef100 entry -
Xenopus tropicalis
Length = 714
Score = 96.7 bits (230), Expect = 4e-18
Identities = 68/217 (31%), Positives = 103/217 (47%), Gaps = 18/217 (8%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA--T 791
E G +F QK LDRE+ ++R V+A +G G V IY+ D NDN P F A +
Sbjct: 26 ERGNVFVQKALDREEHGLWRFVVLATDEEGE-GLTGFADVIIYVVDINDNAPQFTCALSS 84
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ EN T + + A D +E NA+ Y++ +F ++ NTG + +G+
Sbjct: 85 CNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSMLNNTMNLFSINANTGTIYTLGN 144
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE--TK 909
LDREK Y L + D GGL++ I + D ND+ P F Q NS + + TK
Sbjct: 145 -LDREKNDKYVLLVKVIDGGGLATTGTATISVLDINDHVPRFTQDSWNSVILETNDINTK 203
Query: 910 L------------NGTAGFTIIEVKPKNKFALDVDQL 934
+ N F+II+ P KF ++ D++
Sbjct: 204 VLEVSASDEDIGENALLTFSIIDGDPDQKFTIESDRM 240
Score = 77.0 bits (181), Expect = 4e-12
Identities = 101/386 (26%), Positives = 163/386 (42%), Gaps = 43/386 (11%)
Query: 980 KLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD--GGNLNDNISVRVFV 1035
K S F I+E G+V V ++L E +R + A D G L V ++V
Sbjct: 9 KYSLHGKGANNIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGEGLTGFADVIIYV 68
Query: 1036 KDVNDHFPVF--KKTWYNFNVEE---AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
D+ND+ P F + N NV E T + VDA D + NA LTY + + +
Sbjct: 69 VDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSMLNNTMN 128
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
L F I+ TG + G LDRE DKY+L V D G D+ND+ P+
Sbjct: 129 L-FSINANTGTIYTLGNLDREKNDKYVLLVKVIDGG---GLATTGTATISVLDINDHVPR 184
Query: 1151 FYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVA-----KVFANDTD 1205
F W + +N V+ + I ENA + ++ + F ++D
Sbjct: 185 FTQD----SWNSVILE--TNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKFTIESD 238
Query: 1206 FIGNGNGLILYSLPQRKNQQ----NLGL----PSLSSTAILMVTVADVPDEVEMSDKPVF 1257
+ N + L +N Q NL + P SS + + + D D + PVF
Sbjct: 239 RMTNQAEIKLKKKLDYENPQERWFNLTIKVEDPDFSSLSFCFIELQDCND-----NAPVF 293
Query: 1258 ISRYYELE-IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGT 1314
++ + +L + ENV L + ++ N ++RY I +D+ F +DP G
Sbjct: 294 LAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIW--PSSDVLGEFFVDPA-GF 350
Query: 1315 LYLVRSPDREVKDTYEVIVRAERQKY 1340
+ + ++ DREV Y +++ A + +
Sbjct: 351 VKVKKALDREVDSQYHLVILASDEGF 376
Score = 76.6 bits (180), Expect = 5e-12
Identities = 58/185 (31%), Positives = 97/185 (52%), Gaps = 18/185 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVN----GSLFLEKELDLDAEHNLQANTFV 273
+ A D+D+G A L + +I G+ + F+++S + L+K+LD + N Q F
Sbjct: 207 VSASDEDIGENALLTFSIIDGDPDQKFTIESDRMTNQAEIKLKKKLDYE---NPQERWFN 263
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS-IVENLPNGFSVLQVMATD 332
L ++ + +P ++ + IEL D NDN P F F +S ++EN+ G + QV+A+D
Sbjct: 264 LTIK---VEDPDFSSLSFCFIELQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASD 320
Query: 333 KDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN-P 388
D G NG+ Y + D G F +DP +G++ V+ LDRE S + + A + P
Sbjct: 321 ADSGINGQIRYSIWPSSDVLGEFFVDP-AGFVKVKK--ALDREVDSQYHLVILASDEGFP 377
Query: 389 SVVGT 393
S G+
Sbjct: 378 SQTGS 382
Score = 70.9 bits (166), Expect = 2e-10
Identities = 70/276 (25%), Positives = 118/276 (42%), Gaps = 21/276 (7%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I E I T +++++A D D G N + + + +D + + + ++
Sbjct: 193 VILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKFTIESDRMTNQAEIKLKKKL 252
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN-VEEA 1057
+ P E F L I D + + + ++D ND+ PVF + + V E
Sbjct: 253 DY-----ENPQERWFNLTIKVEDP-DFSSLSFCFIELQDCNDNAPVFLAPFVQLSPVLEN 306
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-PFEISPLTGVLSVNGELDRETEDKY 1116
VL +V A+DAD G N + Y I PS L F + P G + V LDRE + +Y
Sbjct: 307 VTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGEFFVDP-AGFVKVKKALDREVDSQY 365
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESV 1176
L ++A D G DVNDN P+ A+ +++ + +D L +++
Sbjct: 366 HLVILASDEG-FPSQTGSATVSFSLLDVNDNGPENTAWPQIVH-MNESSDLLYASDYD-- 421
Query: 1177 MMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
T+E P ++ + N TDF+ N NG
Sbjct: 422 --------TLENGPPFRFSLPSEYTNSTDFLLNDNG 449
Score = 68.5 bits (160), Expect = 1e-09
Identities = 75/295 (25%), Positives = 132/295 (44%), Gaps = 25/295 (8%)
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDV 669
LHG F ++E G + V L R ++ F +A +E L+ + ++VVD+
Sbjct: 12 LHGKGANNIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGEGLTGFADVIIYVVDI 71
Query: 670 NDERGVL---LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV 726
ND L ++ + +V N+ + T + + N N + +
Sbjct: 72 NDNAPQFTCALSSCNANVYENVPPNTTVLEM-----TAVDADDKNEEINAILTYSMLNNT 126
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ +I A GTI+T LDREK D Y + ++ + G ++ G TI + D ND+ P
Sbjct: 127 MNLFSINANTGTIYTLGNLDREKNDKY-VLLVKVIDGGGLATTG--TATISVLDINDHVP 183
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDE--- 841
F ++ I+E + I T++ + A+D D G NAL +++ G+ + F ++
Sbjct: 184 RFTQDSWNSVILETNDINTKVLE---VSASDEDIGENALLTFSIIDGDPDQKFTIESDRM 240
Query: 842 -NTGVVKFIGDSLDRE--KKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
N +K + LD E ++ + L++ D SS + I + D NDN P F
Sbjct: 241 TNQAEIK-LKKKLDYENPQERWFNLTIKVEDP-DFSSLSFCFIELQDCNDNAPVF 293
Score = 62.9 bits (146), Expect = 7e-08
Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 13/155 (8%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D G +L+Y L +F++D G++F++K LD + EH L FV V A+
Sbjct: 1 DNGAHGSLKYSLHGKGANNIFTIDEERGNVFVQKALDRE-EHGLWR--FV--VLATDEEG 55
Query: 284 PLKTAQARVEIELLDLNDNLPEF--EVDFYNISIVENLPNGFSVLQ---VMATDKDQGEN 338
T A V I ++D+NDN P+F + N ++ EN+P +VL+ V A DK++ N
Sbjct: 56 EGLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEIN 115
Query: 339 GEFTY-QLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
TY L++ FSI+ +G T+ LDRE
Sbjct: 116 AILTYSMLNNTMNLFSINANTG--TIYTLGNLDRE 148
Score = 62.1 bits (144), Expect = 1e-07
Identities = 106/468 (22%), Positives = 190/468 (40%), Gaps = 53/468 (11%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQ---N 492
E L F +V + ++D NDN P F + + ++ N T + ++ AVD D N
Sbjct: 56 EGLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEIN 115
Query: 493 GMVLYD-LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERR 549
++ Y L T NL F IN NTGT+ + E ++ L V+ D +
Sbjct: 116 AILTYSMLNNTMNL-----FSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGT 170
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVS 607
+++V+ I +P F + + I T V ++ +D E ++
Sbjct: 171 ATISVLDIN---------DHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLT 221
Query: 608 YDLLHGYEEGVPFAVEE----RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
+ ++ G + F +E I + L N F E+ + S ++
Sbjct: 222 FSIIDG-DPDQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVEDPDFSSLSFCF 280
Query: 664 VHVVDVNDERGVLLKG--AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ + D ND V L SP++ +V + G + Q+ ++ S G +R+ I
Sbjct: 281 IELQDCNDNAPVFLAPFVQLSPVLENV---TIGTVLTQVIASDADS---GINGQIRYSIW 334
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
DV + + G + +K LDRE Y + ++A ++G S G V+ + D N
Sbjct: 335 PSSDVLGEFFVDPAGFVKVKKALDREVDSQYHLVILAS-DEGFPSQTGSATVSFSLLDVN 393
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKE----- 835
DN P E+ + + N + +++ A+D D N F ++L E
Sbjct: 394 DNGP--ENTAWPQIVHMN-------ESSDLLYASDYDTLENGPPFRFSLPSEYTNSTDFL 444
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ D NT V + + DREK + L ++ D+G A +++I
Sbjct: 445 LNDNGNNTATVHAL-RAFDREKDKEFYLPIIITDSGNPPMSATNMLLI 491
Score = 60.9 bits (141), Expect = 3e-07
Identities = 43/140 (30%), Positives = 74/140 (52%), Gaps = 10/140 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D++ + A L Y +++ N LFS+++ G+++ +LD E N + +VL V+
Sbjct: 105 VDADDKNEEINAILTYSMLN-NTMNLFSINANTGTIYTLG--NLDREKN---DKYVLLVK 158
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
T A + + LD+ND++P F D +N I+E VL+V A+D+D GE
Sbjct: 159 VIDGGGLATTGTATISV--LDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGE 216
Query: 338 NGEFTYQL--DDPKGAFSID 355
N T+ + DP F+I+
Sbjct: 217 NALLTFSIIDGDPDQKFTIE 236
Score = 54.8 bits (126), Expect = 2e-05
Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 818 DEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LS 874
D G + Y+L G+G +F +DE G V F+ +LDRE+ +++ ++A D G L+
Sbjct: 1 DNGAHGSLKYSLHGKGANNIFTIDEERGNV-FVQKALDREEHGLWRFVVLATDEEGEGLT 59
Query: 875 SEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA-GFTIIEVKPKNK 926
A++II + D NDN P+F + ++ N T T ++ KN+
Sbjct: 60 GFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNE 112
Score = 48.4 bits (110), Expect = 0.002
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T +E D +SF +E L D NDN PVF+ + + N +GTV+ +V A D D
Sbjct: 265 TIKVEDPDFSSLSFCFIE--LQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDAD 322
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV--AESPILEGRHALFVEASDQ 541
G NG + Y + +S+ + F ++P G V V A ++ ++ L + ASD+
Sbjct: 323 SGINGQIRYSIWPSSD--VLGEFFVDP-AGFVKVKKALDREVDSQYHLVILASDE 374
Score = 38.7 bits (86), Expect = 1.2
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G+ +RY + +D + V+ + F++ + LD E + Q + +L AS
Sbjct: 318 ASDADSGINGQIRYSIWPSSD--VLGEFFVDPAGFVKVKKALDREVDSQYHLVIL---AS 372
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPE 305
P +T A V LLD+NDN PE
Sbjct: 373 DEGFPSQTGSATVSFSLLDVNDNGPE 398
>UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|Rep:
Isoform 2 of Q9UN73 - Homo sapiens (Human)
Length = 686
Score = 96.7 bits (230), Expect = 4e-18
Identities = 130/496 (26%), Positives = 198/496 (39%), Gaps = 84/496 (16%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
++G +F +DRE+ V ++ V + + D NDNPP+F
Sbjct: 80 QNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQR 139
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I E+ + ++ A+DAD G+N++ Y L E F +D VK D
Sbjct: 140 VLIYESRLPDSVFPLEG---ASDADVGSNSILTYKL--SSSEYFGLD-----VKINSDD- 188
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+++ ++ K SL + + A + + + KPE L GT
Sbjct: 189 NKQIGLLLKKSLDREE-----APAHNLFLTATDG-GKPE-----------------LTGT 225
Query: 914 AGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE 973
++ V N A +Q I EN GTT+I+LNA D D G NG I Y FNS
Sbjct: 226 VQL-LVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSL 284
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNI 1029
V A V +F I+ G +++ +L E E +++ I A D G+ + +
Sbjct: 285 V----------AAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHC 334
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V + D ND+ P T + V E V+ + D D G N + + P
Sbjct: 335 TVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTP--- 391
Query: 1090 DLPFE-ISPLTGVLS--VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
+PF+ +S S ++ LDRE+ Y L V ARD G D+ND
Sbjct: 392 HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG-SPSLWATASLSVEVADMND 450
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N+P F PE Y ++EN P G + V A D D
Sbjct: 451 NAPAF---------AQPE-----------------YTVFVKENNPPGCHIFTVSARDAD- 483
Query: 1207 IGNGNGLILYSLPQRK 1222
N L+ YSL +R+
Sbjct: 484 -AQENALVSYSLVERR 498
Score = 78.2 bits (184), Expect = 2e-12
Identities = 53/162 (32%), Positives = 83/162 (51%), Gaps = 14/162 (8%)
Query: 220 AIDQDLGVGATLRYELIS----GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
A D D+G + L Y+L S G D K+ S D+ L L+K LD + +A L
Sbjct: 157 ASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDRE-----EAPAHNLF 211
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ A+ P T ++ + +LD+NDN P FE Y + I EN NG +V+++ A+D+D+
Sbjct: 212 LTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDE 271
Query: 336 GENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDRE 372
G NG +Y + A FSID +G + +R ++E
Sbjct: 272 GANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
Score = 65.7 bits (153), Expect = 9e-09
Identities = 76/330 (23%), Positives = 137/330 (41%), Gaps = 26/330 (7%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+L V + VT+LD NDN P F S YE + NA GT + ++ A D D G NG + Y
Sbjct: 221 ELTGTVQLLVTVLDVNDNAPTFEQSE-YEVRIFENADNGTTVIRLNASDRDEGANGAISY 279
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPIL--EGRHALFVEASDQPANPSERRYSLAVV 555
+ F I+ NTG + + + E + + ++A+D+ P ++ V
Sbjct: 280 SFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVR 339
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++ ++P+ V + GT + I VND + + +
Sbjct: 340 ILD-------KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDL--DSGANGQVNCSLT 390
Query: 616 EGVPF-AVEERSGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
VPF V ++V D L R + Y+ A + +L + +V V D+ND
Sbjct: 391 PHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMND 450
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI----ANQQDVT 727
+ ++ +F VKEN+ IF + V + + ++ ++
Sbjct: 451 NAPAFAQPEYT--VF-VKENNPPGC--HIFTVSARDADAQENALVSYSLVERRVGERALS 505
Query: 728 DDIAI-AEDGTIFTQKPLDREKRDVYRMTV 756
I++ AE G ++ +PLD E+ ++ + V
Sbjct: 506 SYISVHAESGKVYALQPLDHEELELLQFQV 535
Score = 64.1 bits (149), Expect = 3e-08
Identities = 88/406 (21%), Positives = 156/406 (38%), Gaps = 23/406 (5%)
Query: 431 NIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLG 490
++E ++ + +V+V + D NDN P+F P + + +V A D D+G
Sbjct: 105 HLEVIVDRPLQVFHVDVEVRDINDNPPLF-PVEEQRVLIYESRLPDSVFPLEGASDADVG 163
Query: 491 QNGMVLYDLQRTS--NLTITSPFKINPNTGTVSVAESPILEG-RHALFVEASDQPANPSE 547
N ++ Y L + L + N G + E H LF+ A+D
Sbjct: 164 SNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELT 223
Query: 548 RRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QND 605
L V ++V + P F + YE + N GT+V ++ +D E
Sbjct: 224 GTVQLLVTVLDVN-------DNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGA 276
Query: 606 VSYDLLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
+SY V F+++ +G I + +L +Y + + + + + T
Sbjct: 277 ISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKI-LIDATDKGHPPMAGHCT 335
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V +V + D+ + + A + + V+E++ + + N + G V +
Sbjct: 336 V-LVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVN--DLDSGANGQVNCSLTPH 392
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
++ LDRE Y + V A + G S +++ + D NDN
Sbjct: 393 VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR-DGGSPSLWATASLSVEVADMNDN 451
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
P F Y F+ EN+ G I + A DAD NAL Y+L
Sbjct: 452 APAFAQPEYTVFVKENNPPGCHI---FTVSARDADAQENALVSYSL 494
Score = 62.5 bits (145), Expect = 9e-08
Identities = 65/237 (27%), Positives = 101/237 (42%), Gaps = 10/237 (4%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+DVND + + IF +N G + ++ ++ NG + F
Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADN--GTTVIRLNASDRDE-GANGAISYSFNSLVA 286
Query: 724 QDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
V D +I + G I + LD E+ ++Y++ + A +KG AG V + I D+ND
Sbjct: 287 AMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDAT-DKGHPPMAGHCTVLVRILDKND 345
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
N P + + E+++ GT I + I D D G N +L
Sbjct: 346 NVPEIALTSLSLPVREDAQFGTVIAL---ISVNDLDSGANGQVNCSLTPHVPFKLVSTFK 402
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIE 897
+ +LDRE Y+L + ARD G S + A L + + D NDN P F Q E
Sbjct: 403 NYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE 459
Score = 60.9 bits (141), Expect = 3e-07
Identities = 44/188 (23%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Query: 218 IHAIDQDLGVGATLRYE---LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D+D G + Y L++ FS+D G + + LD + E N + +
Sbjct: 264 LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE-----NLYKI 318
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A+ +P V + +LD NDN+PE + ++ + E+ G + + D D
Sbjct: 319 LIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLD 378
Query: 335 QGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G NG+ L + + ++ + LDRE+ S+ + V A++ +PS+ T
Sbjct: 379 SGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438
Query: 394 FADSQRIA 401
+ S +A
Sbjct: 439 ASLSVEVA 446
Score = 59.3 bits (137), Expect = 8e-07
Identities = 70/294 (23%), Positives = 115/294 (39%), Gaps = 26/294 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
L G +++ + + V + DVNDN P F + Y V + E G +
Sbjct: 212 LTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDE 271
Query: 127 SLTIPLTVP-RGLTIFKDIRAFDRDKPNT-----------PNSDVHYSIVSGNDDGHFAL 174
++ L I F D+ NT +++ ++ D GH +
Sbjct: 272 GANGAISYSFNSLVAAMVIDHFSIDR-NTGEIVIRGNLDFEQENLYKILIDATDKGHPPM 330
Query: 175 ESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATL 231
+ H VL+ ++LD + D ++ + + + ++ F I I D D G +
Sbjct: 331 -AGHCTVLV--RILDKN--DNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQV 385
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
L KL S SL L+ LD ++ + + L V A +P A A
Sbjct: 386 NCSLTPHVPFKLVSTFKNYYSLVLDSALDRES-----VSAYELVVTARDGGSPSLWATAS 440
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
+ +E+ D+NDN P F Y + + EN P G + V A D D EN +Y L
Sbjct: 441 LSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
Score = 40.7 bits (91), Expect = 0.30
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P L+ T L+VTV DV D + P F YE+ I EN + ++ LN ++ E
Sbjct: 218 GKPELTGTVQLLVTVLDVND-----NAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEG 272
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N + Y + + F ID G + + + D E ++ Y++++ A
Sbjct: 273 ANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDA 322
>UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadherin
beta 20; n=11; Gallus gallus|Rep: PREDICTED: similar to
protocadherin beta 20 - Gallus gallus
Length = 1166
Score = 96.3 bits (229), Expect = 6e-18
Identities = 170/734 (23%), Positives = 277/734 (37%), Gaps = 102/734 (13%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V ++D NDN P V S+ + + N + GTV+ + D D G NG +
Sbjct: 256 LSALCKVLVEVMDVNDNAPEIVVSS-FSSPIPENVETGTVVALLAVRDQDSGANGEISCA 314
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L+ + + FK TVS + +H + V A+D + P ++ +V +
Sbjct: 315 LEEQPSFALRPAFKNYYELVTVSTLDREE-RAQHMVVVTAADAGSPPLTSTHTFSVDISD 373
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL--HGY 614
V + P F Y +V N VG ++ DA + VSY ++ G
Sbjct: 374 VN-------DNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGP 426
Query: 615 EEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDV 669
EE +V SG + V+ L Y + + E V +A LS + + VVD
Sbjct: 427 EEEPCSCVSVNSESGGVFVLRPLD-YEQ-LRQLEVVVSAADAGSPPLSSSVSVRLLVVDE 484
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND ++P++ H + + + R IA+
Sbjct: 485 ND---------NAPLVLHPSAQDSSPPSSETRGWPRRKLLA-----FRARIASPAGRQHF 530
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G + + LDRE+ T F + + + + +ED ND+ PVF
Sbjct: 531 RLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPD 590
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
I E ++ G+ + EG + FDVD N
Sbjct: 591 ERVTFKIAELTEPGSRFPV-----------------------EGAQDFDVDSND----IQ 623
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
S+ E K + +S ++ G + + L + E ++ +F + +
Sbjct: 624 AYSIIPENKF-FTVSYEKKNEGDIQVQLVLQQPLDREEQSELDFTLVATDGG-----SPP 677
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGL 962
+GT II +DV+ P+F I E+ P G+ ++++ A D D G
Sbjct: 678 RSGTTQIHII--------VMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGT 729
Query: 963 NGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISAL 1020
NG I Y+F+ V S F IN +G + V L E+ ++ L + A
Sbjct: 730 NGDISYQFSQVVSQSQSA-----------FTINTTNGEIRVKTPLDFETTHKYELGVRAT 778
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
DGG L+ V V V DVND+ P + ++ + E V+ + D D G N +
Sbjct: 779 DGGGLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVRDQDSGVNGEI 838
Query: 1081 TYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
T + + L F + P L LDRE ++++ V A D G
Sbjct: 839 TCAL---EEQLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAG-SPPLTSTHTF 894
Query: 1138 XXXXXDVNDNSPKF 1151
DVNDN+P F
Sbjct: 895 SVDISDVNDNAPVF 908
Score = 89.8 bits (213), Expect = 5e-16
Identities = 112/468 (23%), Positives = 186/468 (39%), Gaps = 36/468 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ F +EV++ D ND++PVF P F + + G+ A D D+ N + Y +
Sbjct: 569 LQFFPIEVSVEDINDHSPVF-PDERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSI 627
Query: 500 QRTSNLTITSPFKINPNTGTVS-VAESPILEGRHA---LFVEASDQPANPSERRYSLAVV 555
+ S K N V V + P+ + + A+D + P + ++
Sbjct: 628 IPENKFFTVSYEKKNEGDIQVQLVLQQPLDREEQSELDFTLVATDGGSPPRSGTTQIHII 687
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHG 613
++V + P F Y + + G+ V ++ DA D+SY
Sbjct: 688 VMDVN-------DNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQV 740
Query: 614 YEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
+ F + +G I V L Y+ V + LS + V V+DVND
Sbjct: 741 VSQSQSAFTINTTNGEIRVKTPLDFETTHKYEL-GVRATDGGGLSALCKVLVEVMDVNDN 799
Query: 673 RG-VLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+++ SPI +V+ + A + S + G + + Q A
Sbjct: 800 APEIVVSSFSSPIPENVEPGTVVALLA--VRDQDSGV----NGEITCALEEQLSFALRPA 853
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+ T LDRE+R M V+ + G + ++ I D NDN PVF +
Sbjct: 854 FKNYYELVTVSRLDREER-AQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTS 912
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKE-----MFDVDENTGV 845
Y ++ EN+ + +KATDAD G NA Y++ G E V+ +G
Sbjct: 913 YTMYVHENN---APALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGG 969
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
V F+ LD E+ ++ + A D G LSS + +++ DENDN P
Sbjct: 970 V-FVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAP 1016
Score = 85.0 bits (201), Expect = 1e-14
Identities = 52/155 (33%), Positives = 82/155 (52%), Gaps = 8/155 (5%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
Q PLDRE++ T++A + G +G Q+ I + D NDN P+F H Y G I E++
Sbjct: 126 QHPLDREEQSELDFTLVAT-DGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESA 184
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMY---TLFGEGKEMFDVDENTGVVKFIGDSLDREK 857
G+ + + ATDAD GTN Y + + + F ++ G ++ + LD E
Sbjct: 185 PEGSLVLR---VMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIR-VKTPLDFET 240
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
Y+L + A D GGLS+ ++++ + D NDN PE
Sbjct: 241 THKYELGVRATDGGGLSALCKVLVEVMDVNDNAPE 275
Score = 81.8 bits (193), Expect = 1e-13
Identities = 96/398 (24%), Positives = 173/398 (43%), Gaps = 30/398 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + ++D NDN P+F ++Y + +A G+++ +V A D D+G NG + Y + +
Sbjct: 684 IHIIVMDVNDNAPIFT-HDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVS 742
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ S F IN G + V E H L V A+D + L V +EV
Sbjct: 743 QS-QSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDGGGLSA-----LCKVLVEVM-D 795
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I + + + + NV GT V + V D + + V+ ++ EE + FA+
Sbjct: 796 VNDNAPEI---VVSSFSSPIPENVEPGTVVALLAVRD--QDSGVNGEITCALEEQLSFAL 850
Query: 623 E---ERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
+ + V L R R + A + L+ +V + DVND V +
Sbjct: 851 RPAFKNYYELVTVSRLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQ 910
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIAI-AED 735
+++ +V EN+A A + + N + + A +++ +++ +E
Sbjct: 911 TSYT---MYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSES 967
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G +F +PLD E+ + V A + G + V + + DENDN P+ H + +
Sbjct: 968 GGVFVLRPLDYEQLRQLEVVVSAA-DAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDS 1026
Query: 796 IMENSKI---GTEI-KMDNIIKATDADEGTNALFMYTL 829
+S++ G E + + + A DAD G N+ Y L
Sbjct: 1027 SPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQL 1064
Score = 78.2 bits (184), Expect = 2e-12
Identities = 85/333 (25%), Positives = 134/333 (40%), Gaps = 24/333 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVP-FAVEERSG 627
P F Y + + G+ V ++ DA D+SY + F + +G
Sbjct: 169 PIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNG 228
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG-VLLKGAHSPIIF 686
I V L Y+ V + LS + V V+DVND +++ SPI
Sbjct: 229 EIRVKTPLDFETTHKYEL-GVRATDGGGLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPE 287
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
+V+ G + + + S G + + Q A + T LDR
Sbjct: 288 NVE---TGTVVALLAVRDQDS---GANGEISCALEEQPSFALRPAFKNYYELVTVSTLDR 341
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E+R M V+ + G + ++ I D NDN PVF +Y ++ EN+
Sbjct: 342 EER-AQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENN---APA 397
Query: 807 KMDNIIKATDADEGTNALFMYTLF-GEGKE-----MFDVDENTGVVKFIGDSLDREKKIM 860
+ +KATDAD G NA Y++ G E V+ +G V F+ LD E+
Sbjct: 398 LLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGV-FVLRPLDYEQLRQ 456
Query: 861 YKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
++ + A D G LSS + +++ DENDN P
Sbjct: 457 LEVVVSAADAGSPPLSSSVSVRLLVVDENDNAP 489
Score = 76.6 bits (180), Expect = 5e-12
Identities = 86/343 (25%), Positives = 146/343 (42%), Gaps = 30/343 (8%)
Query: 1010 ESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
+SE + A DGG+ + + + V DVND+ P+F Y ++ E+ ++ +V
Sbjct: 134 QSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRV 193
Query: 1068 DATDADFGQNANLTY-FIQ-PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
ATDAD G N +++Y F Q S + F I+ G + V LD ET KY L V A D
Sbjct: 194 MATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDG 253
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
G DVNDN+P+ + + P + + +++ + +
Sbjct: 254 G---GLSALCKVLVEVMDVNDNAPEIV----VSSFSSPIPENVETGTVVALLAVRDQDSG 306
Query: 1186 IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL--------GLPSLSSTAI 1237
FA F + + +L + + Q++ G P L+ST
Sbjct: 307 ANGEISCALEEQPSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHT 366
Query: 1238 LMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELV-SLNLT--EHYENFKMRYYI 1294
V ++DV D + PVF Y + + EN NAP LV ++ T + N K+ Y +
Sbjct: 367 FSVDISDVND-----NAPVFNQTSYTMYVHEN-NAPALLVGAVKATDADAGPNAKVSYSV 420
Query: 1295 LNEN--DTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
+ + + ++ +G ++++R D E EV+V A
Sbjct: 421 VPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSA 463
Score = 72.9 bits (171), Expect = 6e-11
Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 25/234 (10%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+DV+ P+F I E+ P G+ ++++ A D D G NG I Y+F+ V S
Sbjct: 162 MDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSA- 220
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVN 1039
F IN +G + V L E+ ++ L + A DGG L+ V V V DVN
Sbjct: 221 ----------FTINTTNGEIRVKTPLDFETTHKYELGVRATDGGGLSALCKVLVEVMDVN 270
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISP 1097
D+ P + ++ + E T V+ + D D G N ++ + QPS P
Sbjct: 271 DNAPEIVVSSFSSPIPENVETGTVVALLAVRDQDSGANGEISCALEEQPSFALRP-AFKN 329
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+++V+ LDRE ++++ V A D G DVNDN+P F
Sbjct: 330 YYELVTVS-TLDREERAQHMVVVTAADAG-SPPLTSTHTFSVDISDVNDNAPVF 381
Score = 71.7 bits (168), Expect = 1e-10
Identities = 83/354 (23%), Positives = 152/354 (42%), Gaps = 26/354 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + ++D NDN P+F ++Y + +A G+++ +V A D D+G NG + Y + +
Sbjct: 157 IHIIVMDVNDNAPIFT-HDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVS 215
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRH--ALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ S F IN G + V E H L V A+D +L V +EV
Sbjct: 216 QS-QSAFTINTTNGEIRVKTPLDFETTHKYELGVRATD-----GGGLSALCKVLVEV-MD 268
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I + + + + NV GT V + V D + + + ++ EE FA+
Sbjct: 269 VNDNAPEI---VVSSFSSPIPENVETGTVVALLAVRD--QDSGANGEISCALEEQPSFAL 323
Query: 623 E---ERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
+ + V L R R + A + L+ +V + DVND V +
Sbjct: 324 RPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQ 383
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIAN--QQDVTDDIAI-AED 735
+++ +V EN+A A + + N + + A +++ +++ +E
Sbjct: 384 TSYT---MYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSES 440
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEH 789
G +F +PLD E+ + V++ + G + V + + DENDN P+ H
Sbjct: 441 GGVFVLRPLDYEQLRQLEV-VVSAADAGSPPLSSSVSVRLLVVDENDNAPLVLH 493
Score = 68.5 bits (160), Expect = 1e-09
Identities = 65/220 (29%), Positives = 96/220 (43%), Gaps = 25/220 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI---PPSKLSADALEVKRYFVINE 996
IPEN+ GT + L D DSG+NG+I ++ P K + + V R E
Sbjct: 812 IPENVEPGTVVALLAVRDQDSGVNGEITCALEEQLSFALRPAFKNYYELVTVSR-LDREE 870
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
R H++V ++A D G+ L + V + DVND+ PVF +T Y V
Sbjct: 871 RAQHMVV-------------VTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYV 917
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLP---FEISPLTGVLSVNGELD 1109
E ++G V ATDAD G NA ++Y + P+ + P ++ +G + V LD
Sbjct: 918 HENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLD 977
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
E + + V A D G D NDN+P
Sbjct: 978 YEQLRQLEVVVSAADAG-SPPLSSSVSVRLLVVDENDNAP 1016
Score = 68.1 bits (159), Expect = 2e-09
Identities = 53/207 (25%), Positives = 101/207 (48%), Gaps = 18/207 (8%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D+G + Y+ + + F++++ NG + ++ LD + H + L
Sbjct: 193 VMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYE-----LG 247
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ +A +V +E++D+NDN PE V ++ I EN+ G V + D+D
Sbjct: 248 VRATDGGG--LSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGTVVALLAVRDQDS 305
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
G NGE + L++ + +F++ P + + + LDRE + + V A + +P + T
Sbjct: 306 GANGEISCALEE-QPSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTST 364
Query: 394 FADSQRIAKWRRQPLETNAPL-EKTTY 419
S I+ + NAP+ +T+Y
Sbjct: 365 HTFSVDIS-----DVNDNAPVFNQTSY 386
Score = 67.7 bits (158), Expect = 2e-09
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 11/137 (8%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L L++ LD + + L F L A+ +P ++ ++ I ++D+NDN P F D Y
Sbjct: 650 LVLQQPLDREEQSELD---FTLV--ATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYT 704
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQ----LDDPKGAFSIDPRSGWLTVRNQTV 368
I E+ P G VL+VMATD D G NG+ +YQ + + AF+I+ +G +R +T
Sbjct: 705 GHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNG--EIRVKTP 762
Query: 369 LDREAHSSLRMKVYAKE 385
LD E + V A +
Sbjct: 763 LDFETTHKYELGVRATD 779
Score = 66.9 bits (156), Expect = 4e-09
Identities = 46/137 (33%), Positives = 71/137 (51%), Gaps = 11/137 (8%)
Query: 253 LFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN 312
L L+ LD + + L F L A+ +P ++ ++ I ++D+NDN P F D Y
Sbjct: 123 LVLQHPLDREEQSELD---FTLV--ATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYT 177
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQ----LDDPKGAFSIDPRSGWLTVRNQTV 368
I E+ P G VL+VMATD D G NG+ +YQ + + AF+I+ +G +R +T
Sbjct: 178 GHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNG--EIRVKTP 235
Query: 369 LDREAHSSLRMKVYAKE 385
LD E + V A +
Sbjct: 236 LDFETTHKYELGVRATD 252
Score = 66.5 bits (155), Expect = 5e-09
Identities = 54/207 (26%), Positives = 101/207 (48%), Gaps = 18/207 (8%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D+G + Y+ + + F++++ NG + ++ LD + H + L
Sbjct: 720 VMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYE-----LG 774
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A+ +A +V +E++D+NDN PE V ++ I EN+ G V + D+D
Sbjct: 775 VRATDGGG--LSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVRDQDS 832
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGT 393
G NGE T L++ + +F++ P + + + LDRE + + V A + +P + T
Sbjct: 833 GVNGEITCALEE-QLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAGSPPLTST 891
Query: 394 FADSQRIAKWRRQPLETNAPL-EKTTY 419
S I+ + NAP+ +T+Y
Sbjct: 892 HTFSVDIS-----DVNDNAPVFNQTSY 913
Score = 63.3 bits (147), Expect = 5e-08
Identities = 66/265 (24%), Positives = 109/265 (41%), Gaps = 14/265 (5%)
Query: 635 LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA 693
L R + DF VA + S T + V+DVND + H H+ E++
Sbjct: 129 LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF---THDIYTGHIAESAP 185
Query: 694 -GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY 752
G+ + ++ T+ + + NG + +F Q + +G I + PLD E Y
Sbjct: 186 EGSLVLRVMATD-ADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKY 244
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
+ V A G+ + + +V + + D NDN P +++ I EN + GT + + +
Sbjct: 245 ELGVRATDGGGL---SALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGTVVAL---L 298
Query: 813 KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
D D G N L + +LDRE++ + + + A D G
Sbjct: 299 AVRDQDSGANGEISCALEEQPSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGS 358
Query: 873 --LSSEAELIIMIGDENDNKPEFNQ 895
L+S + I D NDN P FNQ
Sbjct: 359 PPLTSTHTFSVDISDVNDNAPVFNQ 383
Score = 60.9 bits (141), Expect = 3e-07
Identities = 66/265 (24%), Positives = 108/265 (40%), Gaps = 14/265 (5%)
Query: 635 LSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA 693
L R + DF VA + S T + V+DVND + H H+ E++
Sbjct: 656 LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF---THDIYTGHIAESAP 712
Query: 694 -GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY 752
G+ + ++ T+ + + NG + +F Q + +G I + PLD E Y
Sbjct: 713 EGSLVLRVMATD-ADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKY 771
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNII 812
+ V A G+ + + +V + + D NDN P +++ I EN + GT + + +
Sbjct: 772 ELGVRATDGGGL---SALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVAL---L 825
Query: 813 KATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
D D G N L + LDRE++ + + + A D G
Sbjct: 826 AVRDQDSGVNGEITCALEEQLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAGS 885
Query: 873 --LSSEAELIIMIGDENDNKPEFNQ 895
L+S + I D NDN P FNQ
Sbjct: 886 PPLTSTHTFSVDISDVNDNAPVFNQ 910
Score = 53.6 bits (123), Expect = 4e-05
Identities = 75/334 (22%), Positives = 125/334 (37%), Gaps = 24/334 (7%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
LV G S + + + DVNDN PIF Y + E P G +
Sbjct: 668 LVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADV 727
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTP---NSDVHYSIVSGNDDGHFALESSHKPVLL 183
++ + + AF + N + + + + G A + L
Sbjct: 728 GTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDGGGLSALC 787
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELISGN 239
V D D ++V+ + I + + P + A+ DQD GV + L
Sbjct: 788 KVLVEVMDVNDNAPEIVVSSFSSPIPENVE-PGTVVALLAVRDQDSGVNGEITCAL---E 843
Query: 240 DRKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
++ F+L + + L LD E Q ++ V A+ +P T+ +++ D
Sbjct: 844 EQLSFALRPAFKNYYELVTVSRLDREERAQ---HMVVVTAADAGSPPLTSTHTFSVDISD 900
Query: 299 LNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-------DDPKGA 351
+NDN P F Y + + EN V V ATD D G N + +Y + ++P
Sbjct: 901 VNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSC 960
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
S++ SG + V LD E L + V A +
Sbjct: 961 VSVNSESGGVFVLRP--LDYEQLRQLEVVVSAAD 992
Score = 52.0 bits (119), Expect = 1e-04
Identities = 72/333 (21%), Positives = 122/333 (36%), Gaps = 22/333 (6%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP 126
LV G S + + + DVNDN PIF Y + E P G +
Sbjct: 141 LVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADV 200
Query: 127 SLTIPLTVPRGLTIFKDIRAFDRDKPNTP---NSDVHYSIVSGNDDGHFALESSHKPVLL 183
++ + + AF + N + + + + G A + L
Sbjct: 201 GTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDGGGLSALC 260
Query: 184 LRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI---DQDLGVGATLRYELISGND 240
V D D ++V+ + I + + + + DQD G + L +
Sbjct: 261 KVLVEVMDVNDNAPEIVVSSFSSPIPENVETGTVVALLAVRDQDSGANGEISCAL---EE 317
Query: 241 RKLFSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+ F+L + + L LD E Q ++ V A+ +P T+ +++ D+
Sbjct: 318 QPSFALRPAFKNYYELVTVSTLDREERAQ---HMVVVTAADAGSPPLTSTHTFSVDISDV 374
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-------DDPKGAF 352
NDN P F Y + + EN V V ATD D G N + +Y + ++P
Sbjct: 375 NDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCV 434
Query: 353 SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
S++ SG + V LD E L + V A +
Sbjct: 435 SVNSESGGVFVLRP--LDYEQLRQLEVVVSAAD 465
Score = 50.0 bits (114), Expect = 5e-04
Identities = 64/248 (25%), Positives = 102/248 (41%), Gaps = 20/248 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V V ++D NDN P V S+ + + N + GTV+ + D D G NG +
Sbjct: 783 LSALCKVLVEVMDVNDNAPEIVVSS-FSSPIPENVEPGTVVALLAVRDQDSGVNGEITCA 841
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L+ + + FK TVS + +H + V A+D + P ++ +V +
Sbjct: 842 LEEQLSFALRPAFKNYYELVTVSRLDRE-ERAQHMVVVTAADAGSPPLTSTHTFSVDISD 900
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN--DAFEQNDVSYDLL--HGY 614
V + P F Y +V N VG ++ DA VSY ++ G
Sbjct: 901 V-------NDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGP 953
Query: 615 EEG--VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN---LSIVTNATVHVVDV 669
EE +V SG + V+ L Y + + E V +A LS + + VVD
Sbjct: 954 EEEPCSCVSVNSESGGVFVLRPLD-YEQ-LRQLEVVVSAADAGSPPLSSSVSVRLLVVDE 1011
Query: 670 NDERGVLL 677
ND ++L
Sbjct: 1012 NDNAPLVL 1019
Score = 43.6 bits (98), Expect = 0.043
Identities = 54/191 (28%), Positives = 75/191 (39%), Gaps = 10/191 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + D NDN PVF ++ Y + N ++G VKA D D G N V Y
Sbjct: 888 LTSTHTFSVDISDVNDNAPVFNQTS-YTMYVHENNAPALLVGAVKATDADAGPNAKVSYS 946
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAESPILEGRHAL--FVEASDQPANPSERRYSLAV 554
+ R S +N +G V V E L V A+D + P S+ +
Sbjct: 947 VVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRL 1006
Query: 555 VTI-EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QND-VSYDLL 611
+ + E P D P V + G V ++ DA QN +SY LL
Sbjct: 1007 LVVDENDNAPLVLHPSAQD-SSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQLL 1065
Query: 612 HGYEEGVPFAV 622
E G+ FA+
Sbjct: 1066 RATEPGL-FAI 1075
Score = 42.7 bits (96), Expect = 0.075
Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 11/113 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN------AKVGTVIGKVKAVDPDLGQN 492
L S V+V + ++D NDN P+ + + + S S+ A+ G ++ KV AVD D GQN
Sbjct: 998 LSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQN 1057
Query: 493 GMVLYDLQRTS--NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPA 543
+ Y L R + L ++ + G+ +A++ +G++ E D PA
Sbjct: 1058 SWLSYQLLRATEPGLFAIGTVEVFTSQGSSCMAQAAESKGKN---WEKEDLPA 1107
Score = 42.3 bits (95), Expect = 0.099
Identities = 48/184 (26%), Positives = 82/184 (44%), Gaps = 20/184 (10%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L T F++ ++ N A +Q + EN + + A D D+G N ++ Y
Sbjct: 888 LTSTHTFSV-DISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYS 946
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--L 1025
+ P++ + E +N G V V R L E + + +SA D G+ L
Sbjct: 947 ------VVPARGPEE--EPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPL 998
Query: 1026 NDNISVRVFVKDVNDHFP-VFKKTWYNFNVEEAQYTRR------VLGKVDATDADFGQNA 1078
+ ++SVR+ V D ND+ P V + + + ++ ++ KV A DAD GQN+
Sbjct: 999 SSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNS 1058
Query: 1079 NLTY 1082
L+Y
Sbjct: 1059 WLSY 1062
Score = 40.7 bits (91), Expect = 0.30
Identities = 64/289 (22%), Positives = 112/289 (38%), Gaps = 27/289 (9%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI----APIGPSLTIPL 132
+SA V V + DVNDN P + + + + E G + + + + +T L
Sbjct: 783 LSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVRDQDSGVNGEITCAL 842
Query: 133 TVPRGLTI---FKDI-RAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
+ FK+ + + H +V+ D G L S+H + + V
Sbjct: 843 EEQLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVN 902
Query: 189 DYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELIS--GNDRKLFSL 246
D + + + L + A D D G A + Y ++ G + + S
Sbjct: 903 DNAPVFNQTSYTMYVHEN--NAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSC 960
Query: 247 DSVN---GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
SVN G +F+ + LD + L+ + V A+ +P ++ V + ++D NDN
Sbjct: 961 VSVNSESGGVFVLRPLDYEQLRQLE-----VVVSAADAGSPPLSSSVSVRLLVVDENDNA 1015
Query: 304 PEF---EVDFYNISIVENLPNGFS----VLQVMATDKDQGENGEFTYQL 345
P + E +P G V +V+A D D G+N +YQL
Sbjct: 1016 PLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQL 1064
>UniRef50_Q1KKR4 Cluster: Cadherin 5; n=5; Tetraodontidae|Rep:
Cadherin 5 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 773
Score = 95.9 bits (228), Expect = 8e-18
Identities = 67/216 (31%), Positives = 118/216 (54%), Gaps = 22/216 (10%)
Query: 736 GTIFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G +F K LDREK+ +Y +T + + N+ ++ +G ++V + D NDN PVF TY G
Sbjct: 98 GVLFVTKALDREKKSLYHLTARMYDGNRNLVEDSGDFEVQV--TDINDNSPVFP-GTYNG 154
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
IME S IGT++ ++ATDAD+ N Y+L + + F++D TGV+ ++
Sbjct: 155 SIMERSMIGTKVVE---VRATDADDPNTANGELRYSLI-QDQSAFEIDSITGVISCKINT 210
Query: 853 LDREKKIMYKLSLVARDTGGLSS----EAELIIMIGDENDNKPEFNQIEENSKVRIHRET 908
LDRE K Y + + A+D G++S + I I D NDN F + + ++++
Sbjct: 211 LDRETKSQYVVVVKAQDLRGMASGSTATTSVSITITDTNDNIASFTR--RSYELQVPENH 268
Query: 909 KLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENI 944
K+N G +++++ +++ + P F+IP ++
Sbjct: 269 KVNEKIG--VLQLEDRDQ----LQNKEPTFIIPNDM 298
Score = 84.2 bits (199), Expect = 2e-14
Identities = 106/408 (25%), Positives = 181/408 (44%), Gaps = 57/408 (13%)
Query: 996 ERHGHVIVARSLPPESEFRLNISA-LDGGNLN---DNISVRVFVKDVNDHFPVFKKTWYN 1051
+R G + V ++L E + +++A + GN N D+ V V D+ND+ PVF T YN
Sbjct: 95 DRKGVLFVTKALDREKKSLYHLTARMYDGNRNLVEDSGDFEVQVTDINDNSPVFPGT-YN 153
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN-GELDR 1110
++ E + +V ATDAD AN FEI +TGV+S LDR
Sbjct: 154 GSIMERSMIGTKVVEVRATDADDPNTANGELRYSLIQDQSAFEIDSITGVISCKINTLDR 213
Query: 1111 ETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
ET+ +Y++ V A+D G D NDN F E + PE +++
Sbjct: 214 ETKSQYVVVVKAQDLRGMASGSTATTSVSITITDTNDNIASFTR--RSYELQVPENHKVN 271
Query: 1170 NHNFESVMMIPVY-KATIEENAP---IGTTVAKVFANDTDFIGNGNGLI----------- 1214
E + ++ + + ++ P I +++VF + +GN ++
Sbjct: 272 ----EKIGVLQLEDRDQLQNKEPTFIIPNDMSRVFGIELSPNKDGNLMLRKALDFETLNS 327
Query: 1215 -LYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEV-EMSDKPVFISRYYELEI-EENVN 1271
+S+ R+N +NL P+ + + +T A V +V ++ + PVF Y + EE++
Sbjct: 328 YTFSIQVRENLKNLRFPADNVNS--AITAAQVNVKVLDVDEPPVFSQLIYSFTVEEESLG 385
Query: 1272 APVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
+ ++S + N +RY IL + D I ID G ++ DRE++ T+
Sbjct: 386 RNIGVISARDPDR-ANKGIRYSIL-DKDCPI----AIDQITGQFSTLKKLDRELEATHVF 439
Query: 1332 IVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
V+A+ + G+ + VKV V +KD+NDN P+
Sbjct: 440 QVKAQEEP-----------------NGLESF-VKVNVTVKDINDNKPE 469
Score = 65.3 bits (152), Expect = 1e-08
Identities = 104/406 (25%), Positives = 168/406 (41%), Gaps = 50/406 (12%)
Query: 446 EVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD--LGQNGMVLYDLQRTS 503
EV + D NDN+PVF Y S+ + +GT + +V+A D D NG + Y L
Sbjct: 135 EVQVTDINDNSPVF--PGTYNGSIMERSMIGTKVVEVRATDADDPNTANGELRYSL---- 188
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ S F+I+ TG +S + + + ++ + V+A D S S A ++ +T
Sbjct: 189 -IQDQSAFEIDSITGVISCKINTLDRETKSQYVVVVKAQDLRGMASG---STATTSVSIT 244
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
+I F YE V N + +G +++ D + + + + F
Sbjct: 245 --ITDTNDNIASFTRRSYELQVPENHKVNEKIGVLQLEDRDQLQNKEPTFIIPNDMSRVF 302
Query: 621 AVE---ERSGVITVVDDLSRYNRPMYDFEAVALQENANL--------SIVTNATVH--VV 667
+E + G + + L Y F + NL S +T A V+ V+
Sbjct: 303 GIELSPNKDGNLMLRKALDFETLNSYTFSIQVRENLKNLRFPADNVNSAITAAQVNVKVL 362
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
DV DE V + +S F V+E S G IG I + +R+ I D
Sbjct: 363 DV-DEPPVFSQLIYS---FTVEEESLGRNIGVISARDPD----RANKGIRYSIL---DKD 411
Query: 728 DDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
IAI + G T K LDRE + V A+ + +V + ++D NDN P
Sbjct: 412 CPIAIDQITGQFSTLKKLDRELEATHVFQVKAQEEPNGLE--SFVKVNVTVKDINDNKP- 468
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
E A + F+ EN GT + ++ATD D+ + F ++L E
Sbjct: 469 -ELAADDVFLCENDVAGTVL---GTLRATDKDD-SQLSFTFSLASE 509
Score = 65.3 bits (152), Expect = 1e-08
Identities = 79/322 (24%), Positives = 138/322 (42%), Gaps = 31/322 (9%)
Query: 588 IGTSVGQIRVNDAFEQNDVSYDLLHGY-EEGVPFAVEERSGVITV-VDDLSRYNRPMYDF 645
IGT V ++R DA + N + +L + ++ F ++ +GVI+ ++ L R + Y
Sbjct: 162 IGTKVVEVRATDADDPNTANGELRYSLIQDQSAFEIDSITGVISCKINTLDRETKSQYVV 221
Query: 646 --EAVALQENANLSIVTNA-TVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIF 701
+A L+ A+ S T + ++ + D ND + ++ V EN IG +
Sbjct: 222 VVKAQDLRGMASGSTATTSVSITITDTNDNIASFTRRSYE---LQVPENHKVNEKIGVLQ 278
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA--EDGTIFTQKPLDREKRDVYRMTVIAE 759
+ + F+I N I ++ +DG + +K LD E + Y ++
Sbjct: 279 LEDRDQLQNK---EPTFIIPNDMSRVFGIELSPNKDGNLMLRKALDFETLNSYTFSIQVR 335
Query: 760 FN--------KGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
N V S QV + + D D PPVF Y F +E +G I +
Sbjct: 336 ENLKNLRFPADNVNSAITAAQVNVKVLDV-DEPPVFSQLIYS-FTVEEESLGRNI---GV 390
Query: 812 IKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT- 870
I A D D + Y++ + + +D+ TG + LDRE + + + A++
Sbjct: 391 ISARDPDRANKGI-RYSILDKDCPIA-IDQITGQFSTL-KKLDRELEATHVFQVKAQEEP 447
Query: 871 GGLSSEAELIIMIGDENDNKPE 892
GL S ++ + + D NDNKPE
Sbjct: 448 NGLESFVKVNVTVKDINDNKPE 469
Score = 62.5 bits (145), Expect = 9e-08
Identities = 64/223 (28%), Positives = 101/223 (45%), Gaps = 17/223 (7%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
+F++D G LF+ K LD + + + + L + N L E+++ D+NDN
Sbjct: 91 IFTVDR-KGVLFVTKALDREKK-----SLYHLTARMYDGNRNLVEDSGDFEVQVTDINDN 144
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQLDDPKGAFSIDPRSGW 360
P F YN SI+E G V++V ATD D NGE Y L + AF ID +G
Sbjct: 145 SPVFP-GTYNGSIMERSMIGTKVVEVRATDADDPNTANGELRYSLIQDQSAFEIDSITGV 203
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYV 420
++ + T LDRE S + V A++ G+ A + ++ + A + +Y
Sbjct: 204 ISCKINT-LDRETKSQYVVVVKAQDLRGMASGSTATTS-VSITITDTNDNIASFTRRSYE 261
Query: 421 F--PD--KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVF 459
P+ KV K ++ D + N E T + ND + VF
Sbjct: 262 LQVPENHKVNEKIGVLQLEDRDQLQ--NKEPTFIIPNDMSRVF 302
Score = 58.4 bits (135), Expect = 1e-06
Identities = 62/251 (24%), Positives = 108/251 (43%), Gaps = 14/251 (5%)
Query: 624 ERSGVITVVDDLSRYNRPMYDFEAVALQENANL-SIVTNATVHVVDVNDERGVLLKGAHS 682
+R GV+ V L R + +Y A N NL + V V D+ND V G ++
Sbjct: 95 DRKGVLFVTKALDREKKSLYHLTARMYDGNRNLVEDSGDFEVQVTDINDNSPV-FPGTYN 153
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ- 741
I ++ + G + ++ T+ G +R+ + Q + +I G I +
Sbjct: 154 GSI--MERSMIGTKVVEVRATDADD-PNTANGELRYSLIQDQSAFEIDSIT--GVISCKI 208
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGA-GIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
LDRE + Y + V A+ +G+ SG+ V+I I D NDN F +YE + EN
Sbjct: 209 NTLDRETKSQYVVVVKAQDLRGMASGSTATTSVSITITDTNDNIASFTRRSYELQVPENH 268
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD--ENTGVVKFIGDSLDREKK 858
K+ +I +++ D D+ N + + + +F ++ N + +LD E
Sbjct: 269 KVNEKI---GVLQLEDRDQLQNKEPTFIIPNDMSRVFGIELSPNKDGNLMLRKALDFETL 325
Query: 859 IMYKLSLVARD 869
Y S+ R+
Sbjct: 326 NSYTFSIQVRE 336
Score = 56.4 bits (130), Expect = 6e-06
Identities = 47/138 (34%), Positives = 62/138 (44%), Gaps = 10/138 (7%)
Query: 1024 NLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
N+N I+ V V V DV D PVF + Y+F VEE R + G + A D D N +
Sbjct: 347 NVNSAITAAQVNVKVLDV-DEPPVFSQLIYSFTVEEESLGRNI-GVISARDPDRA-NKGI 403
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y I D D P I +TG S +LDRE E ++ V A++
Sbjct: 404 RYSIL--DKDCPIAIDQITGQFSTLKKLDRELEATHVFQVKAQEE--PNGLESFVKVNVT 459
Query: 1141 XXDVNDNSPKFYAFDELL 1158
D+NDN P+ A D L
Sbjct: 460 VKDINDNKPELAADDVFL 477
Score = 49.2 bits (112), Expect = 9e-04
Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK--TA 288
LRY LI D+ F +DS+ G + K LD E Q +V+ V+A L TA
Sbjct: 184 LRYSLIQ--DQSAFEIDSITGVISC-KINTLDRETKSQ---YVVVVKAQDLRGMASGSTA 237
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DD 347
V I + D NDN+ F Y + + EN + + D+DQ +N E T+ + +D
Sbjct: 238 TTSVSITITDTNDNIASFTRRSYELQVPENHKVNEKIGVLQLEDRDQLQNKEPTFIIPND 297
Query: 348 PKGAFSID---PRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F I+ + G L +R LD E +S + +E
Sbjct: 298 MSRVFGIELSPNKDGNLMLRK--ALDFETLNSYTFSIQVRE 336
Score = 47.6 bits (108), Expect = 0.003
Identities = 79/295 (26%), Positives = 125/295 (42%), Gaps = 33/295 (11%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG------PSLTIP 131
+A SV++ I D NDN+ F Y + V E EK + + P+ IP
Sbjct: 236 TATTSVSITITDTNDNIASFTRRSYELQVPENHKVNEKIGVLQLEDRDQLQNKEPTFIIP 295
Query: 132 LTVPR--GLTIF--KDIRAFDRDKPN--TPNSDVHYSIVSGN-DDGHFALESSHKPVLLL 184
+ R G+ + KD R + T NS V N + F ++ + +
Sbjct: 296 NDMSRVFGIELSPNKDGNLMLRKALDFETLNSYTFSIQVRENLKNLRFPADNVNSAITAA 355
Query: 185 R---KVLDYDAGDKEFQLVIMASGKRIHKEILFPE--PIHAIDQDLGVGATLRYELISGN 239
+ KVLD D QL+ + + +E L I A D D +RY ++
Sbjct: 356 QVNVKVLDVDEPPVFSQLIYSFT---VEEESLGRNIGVISARDPDRA-NKGIRYSILD-K 410
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
D + ++D + G K+LD + E T V QV+A + N L++ +V + + D+
Sbjct: 411 DCPI-AIDQITGQFSTLKKLDRELEA-----THVFQVKAQEEPNGLESF-VKVNVTVKDI 463
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
NDN PE D ++ + EN G + + ATDKD + FT+ L FSI
Sbjct: 464 NDNKPELAAD--DVFLCENDVAGTVLGTLRATDKDDSQL-SFTFSLASEASNFSI 515
Score = 41.1 bits (92), Expect = 0.23
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L SFV V VT+ D NDN P +++ + N GTV+G ++A D D Q
Sbjct: 450 LESFVKVNVTVKDINDNKPELAADDVF---LCENDVAGTVLGTLRATDKDDSQLSFTFSL 506
Query: 499 LQRTSNLTI 507
SN +I
Sbjct: 507 ASEASNFSI 515
>UniRef50_Q5DYB4 Cluster: Iron-regulated protein FrpC; n=1; Vibrio
fischeri ES114|Rep: Iron-regulated protein FrpC - Vibrio
fischeri (strain ATCC 700601 / ES114)
Length = 3933
Score = 95.5 bits (227), Expect = 1e-17
Identities = 114/459 (24%), Positives = 196/459 (42%), Gaps = 33/459 (7%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK-AVDPDLGQNGMVLYDLQRTSNLTITSPF 511
ND PV SN E ++ NA++GTV+ A DPD + L D L F
Sbjct: 375 NDVGPV-TDSNTAENTLSENAEIGTVVNITGLATDPDGDEVSYKLSDADIAKGL-----F 428
Query: 512 KINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE-VTRGTKGNKP 568
I+ TG V++ + E H++ + A+ + S+ + + V + T G
Sbjct: 429 AIDATTGVVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDITVTDADGSTPGGGDTDN 488
Query: 569 DI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
D+ P + + N IGT V + + +DV+Y L + FA++ +G
Sbjct: 489 DVGPVTDSNTADNTISENAEIGTVVNITGLATDPDGDDVTYALSQADIDAGLFAIDATTG 548
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPII- 685
V+T++ +L + +A + + S + + V VD + G P+
Sbjct: 549 VVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDIAVTDVDGSTPGGGDTDNDVGPVTD 608
Query: 686 FHVKEN--SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AI-AEDGTIFTQ 741
+ EN S A IG + N++ + + G+ +Q D+ + AI A G +
Sbjct: 609 SNTAENTVSENAEIGSV--VNITGLAADPDGDDVTYALSQADIDAGLFAIDATTGVVTLI 666
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED---------ENDNPPVFEHATY 792
LD E D + +T+IA G S + +T+ D +ND PV + T
Sbjct: 667 GNLDHEVADSHSITIIATSTDGSTSQES-FDITVTDADGSTPGGGDTDNDVGPVTDSNTA 725
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ I EN++IGT + + + D D+ T AL + +F +D TGVV IG +
Sbjct: 726 DNTISENAEIGTVVNITGLATDPDGDDVTYALSQADI---DAGLFAIDATTGVVTLIG-N 781
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
LD E + ++++A T G +S+ I + D + + P
Sbjct: 782 LDHEVADSHSITIIATSTDGSTSQESFDIAVTDVDGSTP 820
Score = 89.0 bits (211), Expect = 9e-16
Identities = 113/459 (24%), Positives = 199/459 (43%), Gaps = 33/459 (7%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK-AVDPDLGQNGMVLYDLQRTSNLTITSPF 511
ND PV SN + ++ NA++GTV+ A DPD G + V Y L + F
Sbjct: 488 NDVGPV-TDSNTADNTISENAEIGTVVNITGLATDPD-GDD--VTYALSQAD--IDAGLF 541
Query: 512 KINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE-VTRGTKGNKP 568
I+ TG V++ + E H++ + A+ + S+ + +AV ++ T G
Sbjct: 542 AIDATTGVVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDIAVTDVDGSTPGGGDTDN 601
Query: 569 DI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
D+ P E V N IG+ V + + +DV+Y L + FA++ +G
Sbjct: 602 DVGPVTDSNTAENTVSENAEIGSVVNITGLAADPDGDDVTYALSQADIDAGLFAIDATTG 661
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPII- 685
V+T++ +L + +A + + S + + TV D + G P+
Sbjct: 662 VVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDITVTDADGSTPGGGDTDNDVGPVTD 721
Query: 686 FHVKEN--SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AI-AEDGTIFTQ 741
+ +N S A IG + N++ + + G+ +Q D+ + AI A G +
Sbjct: 722 SNTADNTISENAEIGTV--VNITGLATDPDGDDVTYALSQADIDAGLFAIDATTGVVTLI 779
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED---------ENDNPPVFEHATY 792
LD E D + +T+IA G S + + + D +ND PV + T
Sbjct: 780 GNLDHEVADSHSITIIATSTDGSTSQES-FDIAVTDVDGSTPGGGDTDNDVGPVTDSNTA 838
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
E + EN++IG+ + + + D D+ T AL + +F +D TGVV IG +
Sbjct: 839 ENTVSENAEIGSVVNITGLAADPDGDDVTYALSQADI---DAGLFAIDATTGVVTLIG-N 894
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
LD E + ++++A T G +S+ I + D ++ P
Sbjct: 895 LDHEVADSHSITIIATSTDGSTSQESFDITVTDIDEIPP 933
Score = 77.4 bits (182), Expect = 3e-12
Identities = 112/462 (24%), Positives = 197/462 (42%), Gaps = 39/462 (8%)
Query: 455 NNPVFVPSNLYEFSMKSN-AKVGTVIG-KVK----AVDPDLGQNGMVLYDLQRTSNLTIT 508
NN + SN+ + ++N T+IG KV A DPD G + V Y L +
Sbjct: 147 NNTII--SNVVDDDTRANLVSENTIIGNKVNITGLATDPD-GDD--VTYALSQAD--IDA 199
Query: 509 SPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE-VTRGTKG 565
F+I+ TG V++ + E H++ + A+ + SE + + V + T G
Sbjct: 200 GLFEIDATTGVVTLIGNLDHEVADSHSITIIATSTDGSTSEASFDITVTDADGSTPGGGD 259
Query: 566 NKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE 624
D+ P + + N IGT V + + +DV+Y L + FA++
Sbjct: 260 TDNDVGPVTDSNAADNTISENAEIGTVVNITGLAVDPDGDDVTYALSQADIDAGLFAIDA 319
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSP 683
+GV+T++ +L + +A + + S + + V D + G P
Sbjct: 320 TTGVVTLIGNLDHDIADSHSITIIATSTDGSTSQESFDIAVTDADGSTPGGGDTDNDVGP 379
Query: 684 II-FHVKEN--SAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQDVTDDIAI-AEDGTI 738
+ + EN S A IG + N++ + + G+ V + +++ AI A G +
Sbjct: 380 VTDSNTAENTLSENAEIGTV--VNITGLATDPDGDEVSYKLSDADIAKGLFAIDATTGVV 437
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED---------ENDNPPVFEH 789
LD E D + +T+IA G S + +T+ D +ND PV +
Sbjct: 438 TLIGNLDHEVADSHSITIIATSTDGSTSQES-FDITVTDADGSTPGGGDTDNDVGPVTDS 496
Query: 790 ATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
T + I EN++IGT + + + D D+ T AL + +F +D TGVV I
Sbjct: 497 NTADNTISENAEIGTVVNITGLATDPDGDDVTYALSQADI---DAGLFAIDATTGVVTLI 553
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
G +LD E + ++++A T G +S+ I + D + + P
Sbjct: 554 G-NLDHEVADSHSITIIATSTDGSTSQESFDIAVTDVDGSTP 594
Score = 55.6 bits (128), Expect = 1e-05
Identities = 84/353 (23%), Positives = 144/353 (40%), Gaps = 19/353 (5%)
Query: 453 NDNNPVFVPSNLYEFSMKSNAKVGTVIGKVK-AVDPDLGQNGMVLYDLQRTSNLTITSPF 511
ND PV SN E ++ NA++G+V+ A DPD G + V Y L + F
Sbjct: 601 NDVGPV-TDSNTAENTVSENAEIGSVVNITGLAADPD-GDD--VTYALSQAD--IDAGLF 654
Query: 512 KINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIE-VTRGTKGNKP 568
I+ TG V++ + E H++ + A+ + S+ + + V + T G
Sbjct: 655 AIDATTGVVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDITVTDADGSTPGGGDTDN 714
Query: 569 DI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSG 627
D+ P + + N IGT V + + +DV+Y L + FA++ +G
Sbjct: 715 DVGPVTDSNTADNTISENAEIGTVVNITGLATDPDGDDVTYALSQADIDAGLFAIDATTG 774
Query: 628 VITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPII- 685
V+T++ +L + +A + + S + + V VD + G P+
Sbjct: 775 VVTLIGNLDHEVADSHSITIIATSTDGSTSQESFDIAVTDVDGSTPGGGDTDNDVGPVTD 834
Query: 686 FHVKEN--SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AI-AEDGTIFTQ 741
+ EN S A IG + N++ + + G+ +Q D+ + AI A G +
Sbjct: 835 SNTAENTVSENAEIGSV--VNITGLAADPDGDDVTYALSQADIDAGLFAIDATTGVVTLI 892
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
LD E D + +T+IA G S I++ NPP T G
Sbjct: 893 GNLDHEVADSHSITIIATSTDGSTSQESFDITVTDIDEIPPNPPTITLDTDSG 945
Score = 38.3 bits (85), Expect = 1.6
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1069 ATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVA 1122
ATD D ++TY + +D D FEI TGV+++ G LD E D + +T++A
Sbjct: 180 ATDPD---GDDVTYALSQADIDAGLFEIDATTGVVTLIGNLDHEVADSHSITIIA 231
Score = 35.9 bits (79), Expect = 8.6
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 1069 ATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVA 1122
ATD D ++TY + +D D F I TGV+++ G LD E D + +T++A
Sbjct: 519 ATDPD---GDDVTYALSQADIDAGLFAIDATTGVVTLIGNLDHEVADSHSITIIA 570
Score = 35.9 bits (79), Expect = 8.6
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 1069 ATDADFGQNANLTYFIQPSDTDLP-FEISPLTGVLSVNGELDRETEDKYILTVVA 1122
ATD D ++TY + +D D F I TGV+++ G LD E D + +T++A
Sbjct: 745 ATDPD---GDDVTYALSQADIDAGLFAIDATTGVVTLIGNLDHEVADSHSITIIA 796
>UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin -
Aedes aegypti (Yellowfever mosquito)
Length = 1653
Score = 95.5 bits (227), Expect = 1e-17
Identities = 85/296 (28%), Positives = 128/296 (43%), Gaps = 21/296 (7%)
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVL 676
G FA+ +G + V L Y+ ++ T V+V DVND V
Sbjct: 18 GDVFAIHNTTGALYVAKALDYEKIKKYELRLTV--SDSFKENYTTVLVNVKDVNDNPPVF 75
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL------IANQQDVTDDI 730
+ ++ I +E+ G + T + + + FL I N + DI
Sbjct: 76 ERSSYRTQI--TEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGIDIENPSESNFDI 133
Query: 731 AIAEDGTIFTQKPLDREK---RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
A G IF KPL+R+ R +++ TV A+ ++G G +V I ++D NDN P F
Sbjct: 134 NKAT-GEIFVLKPLNRDPPHGRPLWKFTVFAQ-DEGGEGLVGFTEVQIKLKDINDNAPSF 191
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------GKEMFDVDE 841
Y G + EN +G + D DEGT+A +Y++ G +FD++
Sbjct: 192 PQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKNAIEEETGLPIFDINP 251
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
+TGV+ LDREK Y L +VA D GGL I + D ND P F + E
Sbjct: 252 DTGVITTAVCCLDREKTPDYSLQIVATDGGGLKGTGTASIKVKDLNDMPPHFTKDE 307
Score = 90.6 bits (215), Expect = 3e-16
Identities = 121/493 (24%), Positives = 205/493 (41%), Gaps = 64/493 (12%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD---LGQNG 493
E L+ F V++ L D NDN P F P +Y ++ N VG + +KA D D G +
Sbjct: 169 EGLVGFTEVQIKLKDINDNAPSF-PQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHA 227
Query: 494 MVLYDLQRTSNLTITS-P-FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYS 551
++Y +++ + T P F INP+TG ++ A V D+ P YS
Sbjct: 228 KIVYSIEKNAIEEETGLPIFDINPDTGVITTA------------VCCLDREKTPD---YS 272
Query: 552 LAVVTIEV--TRGTKGNKPDIPDFMGAPYEF----W------VGSNVGIGTSVGQIRVND 599
L +V + +GT + D P F W N+ + + VND
Sbjct: 273 LQIVATDGGGLKGTGTASIKVKDLNDMPPHFTKDEWFVEVEETDGNILPEAPILTVTVND 332
Query: 600 AFEQNDVSYDLLHGYEEGVP-FAV---EERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
E N+ Y ++ G FA+ + +G + VV L + + +Q N
Sbjct: 333 DDEINNFQYKIIESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDN 392
Query: 656 LSIVTNATVHVVDVNDERGVLLK----GAHSPIIFHVKENSAGAAIGQIFHTNMS----S 707
I HV D V++K ++P + + ++ T +S
Sbjct: 393 EGINDTDKYHV----DHSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAID 448
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG 767
I G + ++I D +I+++GT+ Q+ LDRE Y + ++A + GV
Sbjct: 449 IDKAGKSKITYMINRATDRKRQFSISDEGTVTIQRQLDREAISKYNLEILA-IDDGVPPR 507
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+T+ ++D NDN PVF Y ++ENS I++ + I D F +
Sbjct: 508 TATATLTVEVKDVNDNAPVFAE-EYRPILLENSPASKIIEI-SAIDQDDRRMENGPPFQF 565
Query: 828 TLFGEGKEM----FDVDENT-----GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSE 876
+ + ++ F V++N VV + S DRE + Y++ +V +D+G +
Sbjct: 566 RMDPDADDVIRTSFKVEQNNKGDGMAVVSSL-RSFDREYRKQYEIPIVIKDSGNPAQTGT 624
Query: 877 AELIIMIGDENDN 889
+ L + IGD NDN
Sbjct: 625 STLTVTIGDVNDN 637
Score = 65.3 bits (152), Expect = 1e-08
Identities = 117/485 (24%), Positives = 197/485 (40%), Gaps = 46/485 (9%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLY-EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
++ V V + D NDN PVF S+ + + + + + + +V A D D+ + ++Y L
Sbjct: 57 NYTTVLVNVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFL 116
Query: 500 QRTSNLTITSP----FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVV 555
+ I +P F IN TG + V + + H + A E L
Sbjct: 117 TGPG-IDIENPSESNFDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQ-DEGGEGLVGF 174
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY-DLLHGY 614
T EV K + P F Y V N +G V I+ D + ++ ++ +++
Sbjct: 175 T-EVQIKLKDINDNAPSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSI 233
Query: 615 EE-------GVP-FAVEERSGVITV-VDDLSRYNRPMYDFEAVALQENANLSIVTNATVH 665
E+ G+P F + +GVIT V L R P Y + VA + L A++
Sbjct: 234 EKNAIEEETGLPIFDINPDTGVITTAVCCLDREKTPDYSLQIVAT-DGGGLKGTGTASIK 292
Query: 666 VVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V D+ND K F E + G + + ++ + N ++ I
Sbjct: 293 VKDLNDMPPHFTKDEW----FVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSG 348
Query: 726 V-TDDIAIAED----GTIFTQKPLDRE---KRDVYRMTVIAEFNKGVISGAGIYQVT--- 774
D A+ ++ G++ +PLD E + + +R + N+G I+ Y V
Sbjct: 349 YGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEG-INDTDKYHVDHSW 407
Query: 775 --IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG--TNALFMYTLF 830
+ ++D NDN P F E + EN ++G + KA D D+ + +M
Sbjct: 408 VIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVS---FKAIDIDKAGKSKITYMINRA 464
Query: 831 GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEND 888
+ K F + + V I LDRE Y L ++A D G ++ A L + + D ND
Sbjct: 465 TDRKRQFSISDEGTVT--IQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVND 522
Query: 889 NKPEF 893
N P F
Sbjct: 523 NAPVF 527
Score = 63.7 bits (148), Expect = 4e-08
Identities = 68/254 (26%), Positives = 112/254 (44%), Gaps = 44/254 (17%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
F I+ G + VA++L E ++ L ++ D N +V V VKDVND+ PVF+++
Sbjct: 21 FAIHNTTGALYVAKALDYEKIKKYELRLTVSDSFKENYT-TVLVNVKDVNDNPPVFERSS 79
Query: 1050 YNFNVEEAQ---YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP------FEISPLTG 1100
Y + E +RV+ +V A+DAD + +N+ YF+ D+ F+I+ TG
Sbjct: 80 YRTQITEEDDRGLPKRVM-RVTASDADVERPSNIIYFLTGPGIDIENPSESNFDINKATG 138
Query: 1101 VLSVNGELDRET---EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
+ V L+R+ + TV A+D G D+NDN+P F
Sbjct: 139 EIFVLKPLNRDPPHGRPLWKFTVFAQDEG-GEGLVGFTEVQIKLKDINDNAPSF------ 191
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG-NGLILY 1216
P+ +Y + EN +G V + A D D + G + I+Y
Sbjct: 192 -----PQG---------------IYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVY 231
Query: 1217 SLPQRKNQQNLGLP 1230
S+ + ++ GLP
Sbjct: 232 SIEKNAIEEETGLP 245
Score = 63.7 bits (148), Expect = 4e-08
Identities = 109/430 (25%), Positives = 171/430 (39%), Gaps = 58/430 (13%)
Query: 992 FVINERHGHVIVARSL---PPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPV 1044
F IN+ G + V + L PP ++ + A D G L V++ +KD+ND+ P
Sbjct: 131 FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKDINDNAPS 190
Query: 1045 FKKTWYNFNVEE----AQYTRRVLGKVDATDADFGQNANLTYFIQPS----DTDLP-FEI 1095
F + Y NV E Y + + D D D G +A + Y I+ + +T LP F+I
Sbjct: 191 FPQGIYYGNVTENGTVGMYVMTIKAQ-DNDDVDEGTHAKIVYSIEKNAIEEETGLPIFDI 249
Query: 1096 SPLTGVLSVN-GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
+P TGV++ LDRE Y L +VA D G D+ND P F
Sbjct: 250 NPDTGVITTAVCCLDREKTPDYSLQIVATDGG---GLKGTGTASIKVKDLNDMPPHFTKD 306
Query: 1155 DELLEWKHPEADELSNHNFESVMM-----IPVYKATIEENAPIGTTVAKVFANDTDFIGN 1209
+ +E + + + L +V + I ++ I E++ G A FA + G
Sbjct: 307 EWFVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYG---ADKFAMIKNNDGT 363
Query: 1210 GNGLILYSL----PQRKNQQNLGLPSLSSTAILMVTVADVPDE---VEMSD----KPVFI 1258
G+ ++ L P + N + + I V V++ D P F
Sbjct: 364 GSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFR 423
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
+ E EN LVS + + K + + TD +R F I GT+ +
Sbjct: 424 RPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITYMINRATDRKRQFSISD-EGTVTIQ 482
Query: 1319 RSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
R DRE Y + + A +D + T + V +KDVNDN+P
Sbjct: 483 RQLDREAISKYNLEILA----------------IDDGVPPRTA-TATLTVEVKDVNDNAP 525
Query: 1379 KFTNGNRPLV 1388
F RP++
Sbjct: 526 VFAEEYRPIL 535
Score = 61.3 bits (142), Expect = 2e-07
Identities = 71/271 (26%), Positives = 115/271 (42%), Gaps = 24/271 (8%)
Query: 1013 FRLNISALDGGNLNDNIS-------VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG 1065
FR I D +ND V V +KD+ND+ P F++ E + L
Sbjct: 383 FRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLV 442
Query: 1066 KVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
A D D + +TY I + +D F IS G +++ +LDRE KY L ++A D
Sbjct: 443 SFKAIDIDKAGKSKITYMINRATDRKRQFSISD-EGTVTIQRQLDREAISKYNLEILAID 501
Query: 1125 NGXXXXXXXXXXXXXXXXDVNDNSPKF-YAFDELLEWKHPEAD--ELSNHNFESVMMI-- 1179
+G DVNDN+P F + +L P + E+S + + M
Sbjct: 502 DG-VPPRTATATLTVEVKDVNDNAPVFAEEYRPILLENSPASKIIEISAIDQDDRRMENG 560
Query: 1180 PVYKATIEENA-PIGTTVAKVFANDT-DFIGNGNGLILYSLPQRKNQQ------NLGLPS 1231
P ++ ++ +A + T KV N+ D + + L + RK + + G P+
Sbjct: 561 PPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPA 620
Query: 1232 LSSTAILMVTVADVPDEV-EMSDKPVFISRY 1261
+ T+ L VT+ DV D + + K V + Y
Sbjct: 621 QTGTSTLTVTIGDVNDNIMQPGSKEVVVYNY 651
Score = 56.4 bits (130), Expect = 6e-06
Identities = 49/186 (26%), Positives = 92/186 (49%), Gaps = 19/186 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID D + + Y + DRK S G++ ++++LD +A + + L++ A
Sbjct: 446 AIDIDKAGKSKITYMINRATDRKRQFSISDEGTVTIQRQLDREA-----ISKYNLEILAI 500
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD--QGE 337
P +TA A + +E+ D+NDN P F ++ I ++EN P ++++ A D+D + E
Sbjct: 501 DDGVPPRTATATLTVEVKDVNDNAPVFAEEYRPI-LLENSP-ASKIIEISAIDQDDRRME 558
Query: 338 NG-EFTYQLDDP-----KGAFSIDPRS---GWLTVRNQTVLDREAHSSLRMKVYAKET-N 387
NG F +++D + +F ++ + G V + DRE + + K++ N
Sbjct: 559 NGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGN 618
Query: 388 PSVVGT 393
P+ GT
Sbjct: 619 PAQTGT 624
Score = 55.6 bits (128), Expect = 1e-05
Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 27/219 (12%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN +G T++ A+D+D +I Y N A + KR F I++ G V
Sbjct: 433 ENDEVGKTLVSFKAIDIDKAGKSKITYMINR------------ATDRKRQFSISDE-GTV 479
Query: 1002 IVARSLPPE--SEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ R L E S++ L I A+D G ++ V VKDVND+ PVF + + +E +
Sbjct: 480 TIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPVFAEEYRPILLENS 539
Query: 1058 QYTRRV-LGKVDATDADFGQNANLTYFIQPSDTDL---PFEISPLT-----GVLSVNGEL 1108
++ + + +D D + + P D+ F++ V+S
Sbjct: 540 PASKIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSF 599
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
DRE +Y + +V +D+G DVNDN
Sbjct: 600 DREYRKQYEIPIVIKDSG-NPAQTGTSTLTVTIGDVNDN 637
Score = 48.8 bits (111), Expect = 0.001
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 10/121 (8%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
++RY++ SGN +F++ + G+L++ K LD + + + L++ S + K
Sbjct: 7 SIRYKITSGNIGDVFAIHNTTGALYVAKALDYE-----KIKKYELRLTVS---DSFKENY 58
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGF--SVLQVMATDKDQGENGEFTYQLDD 347
V + + D+NDN P FE Y I E G V++V A+D D Y L
Sbjct: 59 TTVLVNVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTG 118
Query: 348 P 348
P
Sbjct: 119 P 119
Score = 48.8 bits (111), Expect = 0.001
Identities = 47/163 (28%), Positives = 75/163 (46%), Gaps = 14/163 (8%)
Query: 232 RYELI--SGNDRKLFSLDSVN-GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
+Y++I SG F++ N G+ L LD E +Q N F ++Q + T
Sbjct: 340 QYKIIESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTD 399
Query: 289 QARVE-----IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ V+ ++L D+NDN P F EN G +++ A D D+ + TY
Sbjct: 400 KYHVDHSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITY 459
Query: 344 QLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
++ D K FSI G +T++ Q LDREA S +++ A
Sbjct: 460 MINRATDRKRQFSISD-EGTVTIQRQ--LDREAISKYNLEILA 499
Score = 48.4 bits (110), Expect = 0.002
Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 13/152 (8%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F ++ G +F+ K L+ D H F V A V+I+L D+NDN
Sbjct: 131 FDINKATGEIFVLKPLNRDPPHGRPLWKFT--VFAQDEGGEGLVGFTEVQIKLKDINDNA 188
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDK---DQGENGEFTYQ-----LDDPKG--AFS 353
P F Y ++ EN G V+ + A D D+G + + Y +++ G F
Sbjct: 189 PSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKNAIEEETGLPIFD 248
Query: 354 IDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
I+P +G +T LDRE +++ A +
Sbjct: 249 INPDTGVITTA-VCCLDREKTPDYSLQIVATD 279
Score = 45.6 bits (103), Expect = 0.011
Identities = 69/309 (22%), Positives = 126/309 (40%), Gaps = 27/309 (8%)
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLY 465
QPL+ P++ + F +V T E I D+ + V V L D NDN P F ++
Sbjct: 370 QPLDFEDPMQINGFRFRIQV-TDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFRRPHME 428
Query: 466 EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAES 525
++ N +VG + KA+D D + Y + R ++ F I+ + GTV++
Sbjct: 429 AYT-SENDEVGKTLVSFKAIDIDKAGKSKITYMINRATDR--KRQFSIS-DEGTVTIQRQ 484
Query: 526 PILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI-PDFMGAPYEFWV 582
E ++ L + A D P R + A +T+EV + N P ++ E
Sbjct: 485 LDREAISKYNLEILAIDDGVPP---RTATATLTVEV-KDVNDNAPVFAEEYRPILLENSP 540
Query: 583 GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG----VPFAVEERS-----GVITVVD 633
S + + I +D +N + + F VE+ + V++ +
Sbjct: 541 ASKI---IEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLR 597
Query: 634 DLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
R R Y+ V N + + TV + DVND ++ G+ ++++ + +
Sbjct: 598 SFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVND--NIMQPGSKEVVVYNYQGQA 655
Query: 693 AGAAIGQIF 701
IG++F
Sbjct: 656 PDTPIGRVF 664
Score = 45.2 bits (102), Expect = 0.014
Identities = 77/344 (22%), Positives = 138/344 (40%), Gaps = 49/344 (14%)
Query: 620 FAVEERSGVITVVDDLSR---YNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGV 675
F + + +G I V+ L+R + RP++ F A E L T + + D+ND
Sbjct: 131 FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKDINDNAPS 190
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD------ 729
+G + +V EN + GT + + + + +++ ++
Sbjct: 191 FPQGIYYG---NVTENGTVGMYVMTIKAQDNDDVDEGT-HAKIVYSIEKNAIEEETGLPI 246
Query: 730 IAIAEDGTIFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
I D + T LDREK Y + ++A + G + G G +I ++D ND PP F
Sbjct: 247 FDINPDTGVITTAVCCLDREKTPDYSLQIVAT-DGGGLKGTGT--ASIKVKDLNDMPPHF 303
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDEN-- 842
E F+ G + I+ T D+ F Y + G G + F + +N
Sbjct: 304 TKD--EWFVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFAMIKNND 361
Query: 843 -TGVVKFIGDSLDREKKIM---YKLSLVARDTGGLSSEAE-------LIIMIGDENDNKP 891
TG ++ + LD E + ++ + D G++ + +I+ + D NDN P
Sbjct: 362 GTGSLRVV-QPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTP 420
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLG 935
F + + T N G T++ K A+D+D+ G
Sbjct: 421 RFR------RPHMEAYTSENDEVGKTLVSFK-----AIDIDKAG 453
Score = 41.9 bits (94), Expect = 0.13
Identities = 148/656 (22%), Positives = 251/656 (38%), Gaps = 92/656 (14%)
Query: 715 NVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVY--RMTVIAEFNKGVISGAGIY 771
++R+ I + ++ D AI G ++ K LD EK Y R+TV F + +
Sbjct: 7 SIRYKITSG-NIGDVFAIHNTTGALYVAKALDYEKIKKYELRLTVSDSFKENYTT----- 60
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
V + ++D NDNPP + E S T+I ++ D G M
Sbjct: 61 -VLVNVKDVNDNPP----------VFERSSYRTQITEED-------DRGLPKRVMRVTAS 102
Query: 832 EGKEMFDVDENTGVVKFI-GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNK 890
+ DV+ + ++ F+ G +D E + + TG I ++ N +
Sbjct: 103 DA----DVERPSNIIYFLTGPGIDIENPSESNFD-INKATGE-------IFVLKPLNRDP 150
Query: 891 PEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK--NKFALDVDQLGPLFLIPENIPIGT 948
P + + + ++ G GFT +++K K N A Q + EN +G
Sbjct: 151 PHGRPLWKFTVFA--QDEGGEGLVGFTEVQIKLKDINDNAPSFPQGIYYGNVTENGTVGM 208
Query: 949 TIIKLNALD---LDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR 1005
++ + A D +D G + +I Y + L F IN G + A
Sbjct: 209 YVMTIKAQDNDDVDEGTHAKIVYSIEKNAIEEETGLPI--------FDINPDTGVITTAV 260
Query: 1006 S-LPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E ++ L I A DGG L + + VKD+ND P F K + VEE
Sbjct: 261 CCLDREKTPDYSLQIVATDGGGLKGTGTASIKVKDLNDMPPHFTKDEWFVEVEETDGNIL 320
Query: 1063 VLGKV-DATDADFGQNANLTYFIQPS-----DTDLPFEISPLTGVLSVNGELDRETE--- 1113
+ T D + N Y I S D + + TG L V LD E
Sbjct: 321 PEAPILTVTVNDDDEINNFQYKIIESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQI 380
Query: 1114 DKYILTVVARD----NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELS 1169
+ + + D N D+NDN+P+F +E E DE+
Sbjct: 381 NGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFRR--PHMEAYTSENDEVG 438
Query: 1170 NH--NFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL 1227
+F+++ + K+ I T + F+ + + + N + L
Sbjct: 439 KTLVSFKAIDIDKAGKSKITYMINRATDRKRQFSISDEGTVTIQRQLDREAISKYNLEIL 498
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN-VNAPVELVSLNLT 1282
G+P ++TA L V V DV D + PVF Y + +E + + +E+ +++
Sbjct: 499 AIDDGVPPRTATATLTVEVKDVND-----NAPVFAEEYRPILLENSPASKIIEISAIDQD 553
Query: 1283 E-HYENFKMRYYILNENDTDIRRT-FVIDPRN-----GTLYLVRSPDREVKDTYEV 1331
+ EN + ++ + D+ RT F ++ N + +RS DRE + YE+
Sbjct: 554 DRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQYEI 609
Score = 35.9 bits (79), Expect = 8.6
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 24/182 (13%)
Query: 218 IHAIDQD---LGVGATLRYELISGND---RKLFSLDSVN---GSLFLEKELDLDAEHNLQ 268
I AIDQD + G ++ + D R F ++ N G + D E+ Q
Sbjct: 547 ISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQ 606
Query: 269 ANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE---FEVDFYNI-SIVENLPNGFS 324
+ + + NP +T + + + + D+NDN+ + EV YN + P G
Sbjct: 607 ---YEIPIVIKDSGNPAQTGTSTLTVTIGDVNDNIMQPGSKEVVVYNYQGQAPDTPIG-- 661
Query: 325 VLQVMATDKDQGENGEFTYQLDDPKG-AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
+V D D + + + D+ + F +D SG +T+R RE LR K+Y
Sbjct: 662 --RVFVNDLDDWDTSDKLFYWDELENPRFKLDDTSGMVTMRRGA---REGRYKLRFKIYD 716
Query: 384 KE 385
++
Sbjct: 717 RK 718
>UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF14573, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 734
Score = 95.1 bits (226), Expect = 1e-17
Identities = 108/484 (22%), Positives = 202/484 (41%), Gaps = 31/484 (6%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
K E + L + + VT+ D +DN P F P N ++ ++ ++ +V+A+DP
Sbjct: 174 KLEAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLVAQVRAIDP 233
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVE--ASDQPANP 545
D N ++Y L + F ++ TG + +A+ + L ++ AS Q P
Sbjct: 234 DSATNAAIIYSLSPKVSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKVLASSQHCPP 293
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND 605
++ +++++ + R I + + ++ ++ +++F +
Sbjct: 294 ADTLVTVSILP-KAYRELMIKIAFIGEHQKGAMVL-PENQPPTALAILELEGDNSFISSS 351
Query: 606 VSYDLLHGYEEGVPFAVEERSG--VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT 663
++ E VPF++ ++G +++ L + Y VA +A+ S +
Sbjct: 352 LTI------ENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSR 405
Query: 664 ----VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
V V DVND L+ + V+EN+ + H + S G G V +
Sbjct: 406 HILRVMVADVNDNAPNFLRSHYQ---LEVEENNRPGMT--LLHVSASDADGGCNGRVTYR 460
Query: 720 IANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ N + G + LDRE++ + + V A + G V++ + D
Sbjct: 461 LGNHTSTVFSVHPVT-GRLSASTSLDREQQAAHLIRVFAR-DSGSPPLESAATVSVRVLD 518
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV 839
+NDN PVF + F+ E+ + TE+ + +D DEG N M F F V
Sbjct: 519 QNDNAPVFVTPHFIFFVPEDVPLFTEV---GAVSVSDPDEGDNG-NMELFFKNNGGPFCV 574
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQI 896
+ G++ +LD E + Y+L L+A D G L+S + + I + D NDN P+
Sbjct: 575 NSTQGIL-HTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVILP 633
Query: 897 EENS 900
NS
Sbjct: 634 SSNS 637
Score = 83.0 bits (196), Expect = 6e-14
Identities = 75/261 (28%), Positives = 120/261 (45%), Gaps = 18/261 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + D NDN P F+ S+ Y+ ++ N + G + V A D D G NG V Y R N
Sbjct: 408 LRVMVADVNDNAPNFLRSH-YQLEVEENNRPGMTLLHVSASDADGGCNGRVTY---RLGN 463
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
T T F ++P TG +S + S E H + V A D + P E S A V++ V
Sbjct: 464 HTST-VFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLE---SAATVSVRVL-- 517
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ P F+ + F+V +V + T VG + V+D E ++ + +L G PF V
Sbjct: 518 --DQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFF-KNNGGPFCV 574
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQEN--ANLSIVTNATVHVVDVNDE-RGVLLKG 679
G++ +L Y+ +A + L+ + T+ VVDVND V+L
Sbjct: 575 NSTQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVILPS 634
Query: 680 AHSPIIFHVKENSAGAAIGQI 700
++S + + AG + +I
Sbjct: 635 SNSSCLTVPADTIAGTVVTKI 655
Score = 77.8 bits (183), Expect = 2e-12
Identities = 56/179 (31%), Positives = 87/179 (48%), Gaps = 11/179 (6%)
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGNLNDNIS-------VR 1032
S+ +E K F ++ ++G +++ S P + E + +I + G D + +R
Sbjct: 350 SSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSRHILR 409
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP 1092
V V DVND+ P F ++ Y VEE L V A+DAD G N +TY + + T
Sbjct: 410 VMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRL-GNHTSTV 468
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
F + P+TG LS + LDRE + +++ V ARD+G D NDN+P F
Sbjct: 469 FSVHPVTGRLSASTSLDREQQAAHLIRVFARDSG-SPPLESAATVSVRVLDQNDNAPVF 526
Score = 77.0 bits (181), Expect = 4e-12
Identities = 60/215 (27%), Positives = 90/215 (41%), Gaps = 20/215 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G T++ ++A D D G NG++ Y + F ++ G
Sbjct: 431 VEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHT--------------STVFSVHPVTG 476
Query: 1000 HVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + SL E + + + A D G+ L +V V V D ND+ PVF + F V
Sbjct: 477 RLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNAPVFVTPHFIFFVP 536
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E +G V +D D G N N+ F + + PF ++ G+L LD E E +
Sbjct: 537 EDVPLFTEVGAVSVSDPDEGDNGNMELFFKNNGG--PFCVNSTQGILHTTTNLDHEIEQR 594
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
Y L ++A D G DVNDN PK
Sbjct: 595 YELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPK 629
Score = 73.3 bits (172), Expect = 5e-11
Identities = 80/325 (24%), Positives = 134/325 (41%), Gaps = 15/325 (4%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFL-DTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIP 131
G N +SA ++ V + DV+DN P F D P VT+ +P + + I P
Sbjct: 181 GSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSP--RSMLVAQVRAIDPDSATN 238
Query: 132 LTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFAL-----ESSH-KPVLLLR 185
+ L+ RA ++ D+ + +D L S H P L
Sbjct: 239 AAIIYSLSPKVSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKVLASSQHCPPADTLV 298
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPE---PIHAIDQDLGVGATLRYELISGNDRK 242
V +E + I G+ ++ PE P +L + ++ ++
Sbjct: 299 TVSILPKAYRELMIKIAFIGEHQKGAMVLPENQPPTALAILELEGDNSFISSSLTIENKV 358
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
FSL NG L LD E + V+ S + ++ + + + D+NDN
Sbjct: 359 PFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSRHILRVMVADVNDN 418
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL-DDPKGAFSIDPRSGWL 361
P F Y + + EN G ++L V A+D D G NG TY+L + FS+ P +G L
Sbjct: 419 APNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHTSTVFSVHPVTGRL 478
Query: 362 TVRNQTVLDREAHSSLRMKVYAKET 386
+ T LDRE ++ ++V+A+++
Sbjct: 479 SA--STSLDREQQAAHLIRVFARDS 501
Score = 67.7 bits (158), Expect = 2e-09
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 764 VISGAG-IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
V+ +G + Q + IED NDN P FE + ++ E++ +GT + +D ++A D D G N
Sbjct: 73 VVGPSGDLIQFPVIIEDVNDNEPYFEKSEIHLWVSEDATVGTSLLLD--VQAVDRDAGRN 130
Query: 823 ALFMYTLFG-EGKEMFDVDENTGVVKF-IGDSLDREKKIMYKLSLVARDTGG--LSSEAE 878
+ Y L G E+ ++ + +LDRE + Y++ L A D G LS+ A
Sbjct: 131 SEVHYRLEDPNGVFGLTFKEDGPIISLVVQTALDRETRDFYEVKLEAADCGSNPLSATAT 190
Query: 879 LIIMIGDENDNKPEFN 894
LI+ + D +DN P F+
Sbjct: 191 LIVTVTDVDDNCPSFS 206
Score = 59.7 bits (138), Expect = 6e-07
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNP-VFVPS-NLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
Y L S V + ++D NDN P V +PS N ++ ++ GTV+ K+ A+D D G N
Sbjct: 606 YPSALTSTSRVTIFVVDVNDNPPKVILPSSNSSCLTVPADTIAGTVVTKIHAIDEDSGLN 665
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQ 541
V Y + T+ FK++ +G ++ AE + + G H LFV DQ
Sbjct: 666 SEVTYTVVAPEPARSTAVFKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQ 716
Score = 57.2 bits (132), Expect = 3e-06
Identities = 44/168 (26%), Positives = 70/168 (41%), Gaps = 8/168 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G + Y L + +FS+ V G L LD + Q +++V
Sbjct: 444 VSASDADGGCNGRVTYRL-GNHTSTVFSVHPVTGRLSASTSLDRE-----QQAAHLIRVF 497
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A +P + A V + +LD NDN P F + + E++P V V +D D+G+
Sbjct: 498 ARDSGSPPLESAATVSVRVLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGD 557
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG + G F ++ G L T LD E + + A +
Sbjct: 558 NGNMELFFKNNGGPFCVNSTQGIL--HTTTNLDHEIEQRYELYLLASD 603
Score = 56.0 bits (129), Expect = 7e-06
Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 298 DLNDNLPEFEVDFYNISIVENLPNGFSVL-QVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
D+NDN P FE ++ + E+ G S+L V A D+D G N E Y+L+DP G F +
Sbjct: 89 DVNDNEPYFEKSEIHLWVSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLEDPNGVFGLTF 148
Query: 357 RSGW--LTVRNQTVLDREAHSSLRMKVYAKE--TNP 388
+ +++ QT LDRE +K+ A + +NP
Sbjct: 149 KEDGPIISLVVQTALDRETRDFYEVKLEAADCGSNP 184
Score = 55.2 bits (127), Expect = 1e-05
Identities = 64/235 (27%), Positives = 104/235 (44%), Gaps = 15/235 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V V +LD NDN PVFV + + F + + + T +G V DPD G NG + +
Sbjct: 506 LESAATVSVRVLDQNDNAPVFVTPH-FIFFVPEDVPLFTEVGAVSVSDPDEGDNGNM--E 562
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAES--PILEGRHALFVEASDQPANPSERRYSLAVVT 556
L +N PF +N G + + +E R+ L++ ASD+ PS S + VT
Sbjct: 563 LFFKNN---GGPFCVNSTQGILHTTTNLDHEIEQRYELYLLASDR-GYPSALT-STSRVT 617
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLL--H 612
I V N P + V ++ GT V +I D+ ++V+Y ++
Sbjct: 618 IFVV-DVNDNPPKVILPSSNSSCLTVPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPE 676
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
F V+ RSG IT + L + + M+ V + + + T V+++
Sbjct: 677 PARSTAVFKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQGKPIPLYTTVWVNLL 731
Score = 54.8 bits (126), Expect = 2e-05
Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 8/150 (5%)
Query: 1008 PPESEFRLNISALDG--GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV-EEAQYTRRVL 1064
P E+E I L G D I V ++DVND+ P F+K+ + V E+A +L
Sbjct: 58 PEETEAERCIILLTAVVGPSGDLIQFPVIIEDVNDNEPYFEKSEIHLWVSEDATVGTSLL 117
Query: 1065 GKVDATDADFGQNANLTYFIQ-PSDT-DLPF-EISPLTGVLSVNGELDRETEDKYILTVV 1121
V A D D G+N+ + Y ++ P+ L F E P+ L V LDRET D Y + +
Sbjct: 118 LDVQAVDRDAGRNSEVHYRLEDPNGVFGLTFKEDGPIIS-LVVQTALDRETRDFYEVKLE 176
Query: 1122 ARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
A D G DV+DN P F
Sbjct: 177 AADCG-SNPLSATATLIVTVTDVDDNCPSF 205
Score = 52.4 bits (120), Expect = 9e-05
Identities = 79/299 (26%), Positives = 119/299 (39%), Gaps = 27/299 (9%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG---LTIF 141
V + DVNDN P FL + Y + V+E G + +T G T+F
Sbjct: 410 VMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHTSTVF 469
Query: 142 KDIRAFDRDKPNTP----NSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF 197
R +T H V D G LES+ + +VLD + F
Sbjct: 470 SVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESA---ATVSVRVLDQNDNAPVF 526
Query: 198 QLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLE 256
V + +++ LF E D G EL N+ F ++S G L
Sbjct: 527 --VTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFFKNNGGPFCVNSTQGILHTT 584
Query: 257 KELDLDAEHNLQANTFVLQVQASQLNNPLK-TAQARVEIELLDLNDNLPEFEVDFYN--- 312
LD + E + L + AS P T+ +RV I ++D+NDN P+ + N
Sbjct: 585 TNLDHEIEQRYE-----LYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVILPSSNSSC 639
Query: 313 ISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQ 366
+++ + G V ++ A D+D G N E TY + P+ A F +D RSG +T Q
Sbjct: 640 LTVPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRSGNITTAEQ 698
Score = 48.4 bits (110), Expect = 0.002
Identities = 52/201 (25%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F +PE++P+ T + ++ D D G NG + F + P F +N
Sbjct: 532 IFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFFKNNG--GP-------------FCVNS 576
Query: 997 RHGHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFKKTWYN 1051
G + +L E E + L + A D G L V +FV DVND+ P N
Sbjct: 577 TQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVILPSSN 636
Query: 1052 ---FNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVN 1105
V V+ K+ A D D G N+ +TY + +P+ + F++ +G ++
Sbjct: 637 SSCLTVPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRSGNITTA 696
Query: 1106 GELDRETEDKYILTVVARDNG 1126
+L ++ + L VV RD G
Sbjct: 697 EQLLQKDLGMHHLFVVVRDQG 717
Score = 47.2 bits (107), Expect = 0.003
Identities = 47/175 (26%), Positives = 79/175 (45%), Gaps = 17/175 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A+D+D G + + Y L N F D SL ++ LD + + + ++
Sbjct: 120 VQAVDRDAGRNSEVHYRLEDPNGVFGLTFKEDGPIISLVVQTALDRETR-----DFYEVK 174
Query: 276 VQASQL-NNPLKTAQARVEIELLDLNDNLPEFEVDF-YNISIVENLPNGFSVLQVMATDK 333
++A+ +NPL +A A + + + D++DN P F D +++I + P V QV A D
Sbjct: 175 LEAADCGSNPL-SATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLVAQVRAIDP 233
Query: 334 DQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
D N Y L + K FS+D +G +R L + L +KV A
Sbjct: 234 DSATNAAIIYSLSPKVSERAKKLFSLDSLTG--DIRLAQDLHSDTSEELLLKVLA 286
Score = 44.4 bits (100), Expect = 0.024
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ AID D A + Y L +S +KLFSLDS+ G + L ++L D L +L
Sbjct: 228 VRAIDPDSATNAAIIYSLSPKVSERAKKLFSLDSLTGDIRLAQDLHSDTSEEL-----LL 282
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN------ISIVENL-PNGFSVLQ 327
+V AS + P A V + +L ++ F + + EN P ++L+
Sbjct: 283 KVLASSQHCP--PADTLVTVSILPKAYRELMIKIAFIGEHQKGAMVLPENQPPTALAILE 340
Query: 328 VMATDKDQGENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ +G+N + L + K FS+ P++G + LD E S + V A+ T
Sbjct: 341 L------EGDNSFISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGT 394
Query: 387 NPSVVGTFADSQRIAKWRRQPLETNAP 413
+ + A S+ I + + NAP
Sbjct: 395 SADGSAS-APSRHILRVMVADVNDNAP 420
Score = 44.4 bits (100), Expect = 0.024
Identities = 63/274 (22%), Positives = 104/274 (37%), Gaps = 35/274 (12%)
Query: 1088 DTDLPFEISPLTG--VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX--XD 1143
+ +PF +SP G +LS + LD E + Y + VVAR D
Sbjct: 355 ENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSRHILRVMVAD 414
Query: 1144 VNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND 1203
VNDN+P F LE + +N + ++ V + + T
Sbjct: 415 VNDNAPNFLRSHYQLE--------VEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHTS 466
Query: 1204 TDF-IGNGNGLILYSLPQRKNQQ----------NLGLPSLSSTAILMVTVADVPDEVEMS 1252
T F + G + S + QQ + G P L S A + V V D D
Sbjct: 467 TVFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNA--- 523
Query: 1253 DKPVFISRYYELEIEENVNAPVEL--VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDP 1310
PVF++ ++ + E+V E+ VS++ + +N M + N F ++
Sbjct: 524 --PVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFFKNNGGP-----FCVNS 576
Query: 1311 RNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
G L+ + D E++ YE+ + A + Y L
Sbjct: 577 TQGILHTTTNLDHEIEQRYELYLLASDRGYPSAL 610
Score = 44.0 bits (99), Expect = 0.032
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 5/138 (3%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGT-VIGKVKAVDPDLGQNGMVLYDLQR 501
+ V + D NDN P F S ++ + + +A VGT ++ V+AVD D G+N V Y L+
Sbjct: 81 IQFPVIIEDVNDNEPYFEKSEIHLW-VSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLE- 138
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEV 559
N FK + ++ V + E R + + +EA+D +NP +L V +V
Sbjct: 139 DPNGVFGLTFKEDGPIISLVVQTALDRETRDFYEVKLEAADCGSNPLSATATLIVTVTDV 198
Query: 560 TRGTKGNKPDIPDFMGAP 577
PD P + P
Sbjct: 199 DDNCPSFSPDNPRSVTIP 216
Score = 42.7 bits (96), Expect = 0.075
Identities = 52/226 (23%), Positives = 94/226 (41%), Gaps = 17/226 (7%)
Query: 730 IAIAEDGTIFT---QKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ EDG I + Q LDRE RD Y + + A+ +S VT+ D +DN P
Sbjct: 146 LTFKEDGPIISLVVQTALDRETRDFYEVKLEAADCGSNPLSATATLIVTV--TDVDDNCP 203
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDE 841
F + + + ++A D D TNA +Y+L + K++F +D
Sbjct: 204 SFSPDNPRSVTIPGDSPRSMLVAQ--VRAIDPDSATNAAIIYSLSPKVSERAKKLFSLDS 261
Query: 842 NTGVVKFIGD-SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENS 900
TG ++ D D ++++ K+ ++ + + I+ + + I E+
Sbjct: 262 LTGDIRLAQDLHSDTSEELLLKVLASSQHCPPADTLVTVSILPKAYRELMIKIAFIGEHQ 321
Query: 901 KVRIHRETKLNGTAGFTIIEVKPKNKF---ALDVDQLGPLFLIPEN 943
K + TA I+E++ N F +L ++ P L P+N
Sbjct: 322 KGAMVLPENQPPTA-LAILELEGDNSFISSSLTIENKVPFSLSPQN 366
Score = 40.7 bits (91), Expect = 0.30
Identities = 50/176 (28%), Positives = 71/176 (40%), Gaps = 30/176 (17%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVEL--VSLNLTEHY 1285
G S S IL V VADV D P F+ +Y+LE+EEN + L VS + +
Sbjct: 398 GSASAPSRHILRVMVADVNDNA-----PNFLRSHYQLEVEENNRPGMTLLHVSASDADGG 452
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y + N T F + P G L S DRE ++
Sbjct: 453 CNGRVTYRLGNHTST----VFSVHPVTGRLSASTSLDRE-----------------QQAA 491
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQV 1401
H+I A D + V VR+ D NDN+P F + + +P P +V
Sbjct: 492 HLIRVFARDSGSPPLESAATVSVRVLDQNDNAPVFVTPH--FIFFVPEDVPLFTEV 545
>UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|Rep:
Cadherin-5 precursor - Homo sapiens (Human)
Length = 784
Score = 95.1 bits (226), Expect = 1e-17
Identities = 120/459 (26%), Positives = 195/459 (42%), Gaps = 50/459 (10%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV---DPDLGQNG 493
E L + + + + D NDN PVF L+ S+ ++ VGT + V AV DP +G +
Sbjct: 129 ENLETPSSFTIKVHDVNDNWPVFT-HRLFNASVPESSAVGTSVISVTAVDADDPTVGDHA 187
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYS 551
V+Y + + F I+ + +++ +S E R+ + VEA D + +
Sbjct: 188 SVMYQILKGKEY-----FAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTA 242
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVS-YD 609
+VT++ + P F Y F V + +GTSVG + V D E QN ++ Y
Sbjct: 243 TVLVTLQ------DINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYS 296
Query: 610 LLHG-YEEGVPFAVE----ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT---- 660
+L G Y++ F +E G+I + L Y F A +L ++
Sbjct: 297 ILRGDYQDA--FTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAG 354
Query: 661 ---NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR 717
+++ DV DE + + + F +KEN IG + + + ++
Sbjct: 355 NRAQVIINITDV-DEPPIFQQPFYH---FQLKENQKKPLIGTVLAMDPDA----ARHSIG 406
Query: 718 FLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISG-AGIYQVT 774
+ I D + + G I+ +K LDRE Y +TV A+ + G +G I QV
Sbjct: 407 YSIRRTSDKGQFFRVTKKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVH 466
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTLFGEG 833
I + DENDN P F Y+ + EN+ G + I A D D N F +TL E
Sbjct: 467 IEVLDENDNAPEFA-KPYQPKVCENAVHGQLVLQ---ISAIDKDITPRNVKFKFTLNTEN 522
Query: 834 K-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+ D +NT + DRE ++ L +V D G
Sbjct: 523 NFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNG 561
Score = 81.0 bits (191), Expect = 2e-13
Identities = 90/346 (26%), Positives = 154/346 (44%), Gaps = 31/346 (8%)
Query: 585 NVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
N + VG+I+ + + + Y LL G G F V+ +G + ++ L R N Y
Sbjct: 61 NTSLPHHVGKIK--SSVSRKNAKY-LLKGEYVGKVFRVDAETGDVFAIERLDRENISEYH 117
Query: 645 FEAVALQENA--NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIF 701
AV + ++ NL ++ T+ V DVND V H V E+SA G ++ +
Sbjct: 118 LTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVF---THRLFNASVPESSAVGTSVISVT 174
Query: 702 HTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT-QKPLDREKRDVYRMTVIAEF 760
+ +V + I ++ AI G I T K LDREK+ Y + V A
Sbjct: 175 AVDADDPTVGDHASVMYQILKGKEY---FAIDNSGRIITITKSLDREKQARYEIVVEARD 231
Query: 761 NKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+G+ +G V + ++D NDN P F Y + E++++GT + + D DE
Sbjct: 232 AQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSV---GSLFVEDPDEP 288
Query: 821 TNALFMYTLF-GEGKEMFDVD----ENTGVVKFIGDSLDREKKIMYKLSLVARD------ 869
N + Y++ G+ ++ F ++ N G++K + LD E Y + A D
Sbjct: 289 QNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPM-KPLDYEYIQQYSFIVEATDPTIDLR 347
Query: 870 --TGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGT 913
+ + A++II I D D P F Q + +++ +++ L GT
Sbjct: 348 YMSPPAGNRAQVIINITDV-DEPPIFQQPFYHFQLKENQKKPLIGT 392
Score = 74.1 bits (174), Expect = 3e-11
Identities = 102/425 (24%), Positives = 168/425 (39%), Gaps = 50/425 (11%)
Query: 988 VKRYFVINERHGHVIVARSLPPE--SEFRLNISALD---GGNLNDNISVRVFVKDVNDHF 1042
V + F ++ G V L E SE+ L +D G NL S + V DVND++
Sbjct: 89 VGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNW 148
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLT 1099
PVF +N +V E+ + V A DAD G +A++ Y I F I
Sbjct: 149 PVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKE--YFAIDNSG 206
Query: 1100 GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF----YAF- 1154
++++ LDRE + +Y + V ARD D+NDN P F Y F
Sbjct: 207 RIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFV 266
Query: 1155 --------DELLEWKHPEADELSNHNFESVMMIPVYK--ATIEENAPIGTTVAKVFAN-D 1203
+ + DE N + ++ Y+ TIE N + K D
Sbjct: 267 VPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLD 326
Query: 1204 TDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
++I + ++ + P P + A +++ + DV + P+F +Y
Sbjct: 327 YEYIQQYSFIVEATDP--TIDLRYMSPPAGNRAQVIINITDV------DEPPIFQQPFYH 378
Query: 1264 LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+++EN P+ L + + Y I +D + F + G +Y + DR
Sbjct: 379 FQLKENQKKPLIGTVLAMDPDAARHSIGYSIRRTSD---KGQFFRVTKKGDIYNEKELDR 435
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNG 1383
EV Y + V A +EL P ++ + V+V + + D NDN+P+F
Sbjct: 436 EVYPWYNLTVEA------KELDSTGTPTGKESI-------VQVHIEVLDENDNAPEFAKP 482
Query: 1384 NRPLV 1388
+P V
Sbjct: 483 YQPKV 487
Score = 58.8 bits (136), Expect = 1e-06
Identities = 56/194 (28%), Positives = 84/194 (43%), Gaps = 21/194 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE+ +GT++I + A+D D G + S +Y L+ K YF I+
Sbjct: 160 VPESSAVGTSVISVTAVDADDPTVG----DHASVMY--------QILKGKEYFAIDNSGR 207
Query: 1000 HVIVARSLPPESEFRLNI--SALDGGNLNDN---ISVRVFVKDVNDHFPVFKKTWYNFNV 1054
+ + +SL E + R I A D L + +V V ++D+ND+FP F +T Y F V
Sbjct: 208 IITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVV 267
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF--EISPL--TGVLSVNGELDR 1110
E +G + D D QN Y I D F E +P G++ LD
Sbjct: 268 PEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDY 327
Query: 1111 ETEDKYILTVVARD 1124
E +Y V A D
Sbjct: 328 EYIQQYSFIVEATD 341
Score = 58.4 bits (135), Expect = 1e-06
Identities = 90/346 (26%), Positives = 137/346 (39%), Gaps = 38/346 (10%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-----DVSYDLLHGYEEGVPFAVEER 625
P F + V + +GTSV + DA + V Y +L G E FA++
Sbjct: 149 PVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEY---FAIDNS 205
Query: 626 SGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSP 683
+IT+ L R + Y+ A ATV V D+ND + ++
Sbjct: 206 GRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTF 265
Query: 684 IIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDV--TDDIAIAEDGTIFTQ 741
++ ++ G ++G +F + T L + QD + +G I
Sbjct: 266 VV--PEDTRVGTSVGSLFVEDPDEPQNRMT-KYSILRGDYQDAFTIETNPAHNEGIIKPM 322
Query: 742 KPLDREKRDVYRMTVIAE---FNKGVIS--GAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
KPLD E Y V A + +S QV I I D D PP+F+ Y +
Sbjct: 323 KPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DEPPIFQQPFYHFQL 381
Query: 797 MENSK---IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
EN K IGT + MD DA + + +G + F V + + + L
Sbjct: 382 KENQKKPLIGTVLAMD-----PDAARHSIGYSIRRTSDKG-QFFRVTKKGDI--YNEKEL 433
Query: 854 DREKKIMYKLSLVARD---TG---GLSSEAELIIMIGDENDNKPEF 893
DRE Y L++ A++ TG G S ++ I + DENDN PEF
Sbjct: 434 DREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEF 479
Score = 55.6 bits (128), Expect = 1e-05
Identities = 81/300 (27%), Positives = 125/300 (41%), Gaps = 32/300 (10%)
Query: 69 RIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA-FIFLIAPIGPS 127
R GL S +V V ++D+NDN P F T Y V E T G +F+ P P
Sbjct: 230 RDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQ 289
Query: 128 LTIP-LTVPRGLTIFKDIRAFDRD--------KPNTPNSDVH---YSIVSGNDDGHFALE 175
+ ++ RG ++D + + KP P + YS + D L
Sbjct: 290 NRMTKYSILRG--DYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLR 347
Query: 176 SSHKPV----LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATL 231
P ++ + D D Q K K+ L + A+D D ++
Sbjct: 348 YMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQKKPLIGTVL-AMDPD-AARHSI 405
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN---PL-KT 287
Y + +D+ F + G ++ EKELD + + L V+A +L++ P K
Sbjct: 406 GYSIRRTSDKGQFFRVTKKGDIYNEKELDREVYP-----WYNLTVEAKELDSTGTPTGKE 460
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQLD 346
+ +V IE+LD NDN PEF Y + EN +G VLQ+ A DKD N +F + L+
Sbjct: 461 SIVQVHIEVLDENDNAPEFAKP-YQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFTLN 519
Score = 54.4 bits (125), Expect = 2e-05
Identities = 57/202 (28%), Positives = 91/202 (45%), Gaps = 23/202 (11%)
Query: 242 KLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
K+F +D+ G +F + LD + +E++L A V + L P + I++ D+
Sbjct: 91 KVFRVDAETGDVFAIERLDRENISEYHLTA-VIVDKDTGENLETP-----SSFTIKVHDV 144
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GENGEFTYQLDDPKGAFSIDP 356
NDN P F +N S+ E+ G SV+ V A D D G++ YQ+ K F+ID
Sbjct: 145 NDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAIDN 204
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADS-QRIAKWRRQPLETNAPL- 414
+T+ LDRE + + V A++ G DS Q + N P
Sbjct: 205 SGRIITITKS--LDREKQARYEIVVEARDAQ----GLRGDSGTATVLVTLQDINDNFPFF 258
Query: 415 --EKTTYVFPD--KVGTKTENI 432
K T+V P+ +VGT ++
Sbjct: 259 TQTKYTFVVPEDTRVGTSVGSL 280
Score = 45.6 bits (103), Expect = 0.011
Identities = 36/141 (25%), Positives = 69/141 (48%), Gaps = 10/141 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D +G A++ Y+++ G ++ F++D+ + + K LD + + + V++ +
Sbjct: 176 VDADDPTVGDHASVMYQILKG--KEYFAIDNSGRIITITKSLDREKQARYE---IVVEAR 230
Query: 278 ASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+Q L TA V ++ D+NDN P F Y + E+ G SV + D D+
Sbjct: 231 DAQGLRGDSGTATVLVTLQ--DINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEP 288
Query: 337 ENGEFTYQL--DDPKGAFSID 355
+N Y + D + AF+I+
Sbjct: 289 QNRMTKYSILRGDYQDAFTIE 309
Score = 45.6 bits (103), Expect = 0.011
Identities = 88/349 (25%), Positives = 139/349 (39%), Gaps = 33/349 (9%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V VTL D NDN P F + Y F + + +VGT +G + DPD QN M Y + R +
Sbjct: 244 VLVTLQDINDNFPFFTQTK-YTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILR-GD 301
Query: 505 LTITSPFKINP--NTGTVSVAESPILE--GRHALFVEASDQPAN---PSERRYSLAVVTI 557
+ NP N G + + E +++ VEA+D + S + A V I
Sbjct: 302 YQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVII 361
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEG 617
+T + + P F Y F + N + ++ ++ + Y + ++G
Sbjct: 362 NIT-----DVDEPPIFQQPFYHFQLKENQKKPLIGTVLAMDPDAARHSIGYSIRRTSDKG 416
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDF--EAVALQEN---ANLSIVTNATVHVVDVNDE 672
F V ++ G I +L R P Y+ EA L + + V+D ND
Sbjct: 417 QFFRVTKK-GDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDN 475
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT-GNVRFLIANQQDVTDDIA 731
K P V EN A GQ+ +S+I + T NV+F + +
Sbjct: 476 APEFAK----PYQPKVCEN---AVHGQLV-LQISAIDKDITPRNVKFKFTLNTENNFTLT 527
Query: 732 IAEDGTI-FTQK--PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYI 777
D T T K DRE V+ + V+ N G+ S G +T+ +
Sbjct: 528 DNHDNTANITVKYGQFDREHTKVHFLPVVISDN-GMPSRTGTSTLTVAV 575
Score = 44.4 bits (100), Expect = 0.024
Identities = 74/350 (21%), Positives = 141/350 (40%), Gaps = 32/350 (9%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-----IGPSLTIPLTVPR 136
S T+ + DVNDN P+F ++ +V E + G +G ++ + +
Sbjct: 136 SFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILK 195
Query: 137 GLTIF---KDIRAFDRDKPNTPNSDVHYSIV-SGNDDGHFALESSHKPVLL-LRKVLD-Y 190
G F R K Y IV D +S VL+ L+ + D +
Sbjct: 196 GKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNF 255
Query: 191 DAGDKEFQLVIMASGKRIHKEI--LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDS 248
+ ++ R+ + LF E D D +Y ++ G+ + F++++
Sbjct: 256 PFFTQTKYTFVVPEDTRVGTSVGSLFVE-----DPDEPQNRMTKYSILRGDYQDAFTIET 310
Query: 249 --VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN----NPLKTAQARVEIELLDLNDN 302
+ ++ LD E+ +Q +F+++ ++ +P +A+V I + D+ D
Sbjct: 311 NPAHNEGIIKPMKPLDYEY-IQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DE 368
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLDDPKGAFSIDPRSGWL 361
P F+ FY+ + EN + V+A D D + ++ + KG F + G
Sbjct: 369 PPIFQQPFYHFQLKENQKKPL-IGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTKKG-- 425
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETN 411
+ N+ LDRE + + V AKE + + GT + I + + L+ N
Sbjct: 426 DIYNEKELDREVYPWYNLTVEAKELDST--GTPTGKESIVQVHIEVLDEN 473
Score = 40.7 bits (91), Expect = 0.30
Identities = 68/303 (22%), Positives = 110/303 (36%), Gaps = 30/303 (9%)
Query: 1049 WYNFNVEEAQYTR--RVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
W +++E + T +GK+ ++ + N Y ++ F + TG +
Sbjct: 51 WNQMHIDEEKNTSLPHHVGKIKSSVS----RKNAKYLLKGEYVGKVFRVDAETGDVFAIE 106
Query: 1107 ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEAD 1166
LDRE +Y LT V D DVNDN P F L PE+
Sbjct: 107 RLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVF--THRLFNASVPESS 164
Query: 1167 ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILY--SLPQRKN- 1223
+ + SV + T+ ++A + + K + I N +I SL + K
Sbjct: 165 AVGT-SVISVTAVDADDPTVGDHASVMYQILK--GKEYFAIDNSGRIITITKSLDREKQA 221
Query: 1224 --------QQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVE 1275
+ GL S TA ++VT+ D+ D P F Y + E+
Sbjct: 222 RYEIVVEARDAQGLRGDSGTATVLVTLQDINDNF-----PFFTQTKYTFVVPEDTRVGTS 276
Query: 1276 LVSLNLTEHYE-NFKMRYYILNENDTDIRRTFVIDP--RNGTLYLVRSPDREVKDTYEVI 1332
+ SL + + E +M Y + D T +P G + ++ D E Y I
Sbjct: 277 VGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFI 336
Query: 1333 VRA 1335
V A
Sbjct: 337 VEA 339
>UniRef50_Q4SKV9 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 847
Score = 94.7 bits (225), Expect = 2e-17
Identities = 129/541 (23%), Positives = 216/541 (39%), Gaps = 56/541 (10%)
Query: 672 ERGVLLKGAHSPII---FHVKENSAGAA---IGQIFHTNMSSIYGN---GTGNVRFLIAN 722
ER +LL+ A + F V E G IG+ +N ++ + G G++++++
Sbjct: 37 ERSLLLRRAKRGWVWNQFFVLEEYTGLEPLYIGKSVLSNAEQLHSDMDKGDGSIKYILTG 96
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ T G I + LDRE + Y + A + + I+D ND
Sbjct: 97 EGAGTTFTIDDSTGDIHAIQRLDREMKAQYILRAQARNRLTDRPLEPESEFIVKIQDIND 156
Query: 783 NPPVFEHATYEGFIMENSKIG------TEIKMDNIIK--------------------ATD 816
N P F Y + E S+IG + N +K ATD
Sbjct: 157 NEPRFLDGPYWATVPEMSQIGENMGQQASVVSKNCVKNDIQTRHFCLSAGTSVIQVSATD 216
Query: 817 ADE---GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG- 872
AD+ G +A +Y++ EG+ F VD TG+++ +DRE + Y + + A+D GG
Sbjct: 217 ADDPTYGNSARVVYSIL-EGQPYFSVDAKTGMLRVSLADMDRETRENYTVVIQAKDMGGQ 275
Query: 873 ---LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFAL 929
L+ + +M+ D NDN P F+Q + + R+ TA I +++ +
Sbjct: 276 LGGLAGTTTVNVMLTDINDNPPMFDQ-SKRAGARL--------TARHRIAQLRASFQTYF 326
Query: 930 DVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVK 989
++ IPE P+G+ + ++ A D D G+N +++Y +S D +
Sbjct: 327 TLNSGLYQMSIPETAPVGSVVGRIWAKDRDIGINAEMKYSIIDGDGRDTFDISTDPTNLF 386
Query: 990 RYFVINERHG-HVIVARSLPPE-SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
+ + ++ +L E + ++ G D V V V+DV D P+F
Sbjct: 387 GIITVKKPLDFETKLSYTLKVEGANTHVDPHVHHRGPFKDVTIVHVSVEDV-DEPPLFDS 445
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y + E V+ V A D D N + SD D F I +G L
Sbjct: 446 PAYLLELSEDAEIGTVVKTVSARDPDSANNTVRYSIERTSDLDKYFYIDITSGALMTVRT 505
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE + +TV+A + DVNDN P + E ++ +A +
Sbjct: 506 LDREEMSWHNITVLAMEMN-NPSQIASASVAVKITDVNDNPPSLTQYLEAYVCENAKAGQ 564
Query: 1168 L 1168
L
Sbjct: 565 L 565
Score = 62.5 bits (145), Expect = 9e-08
Identities = 86/363 (23%), Positives = 147/363 (40%), Gaps = 32/363 (8%)
Query: 319 LPNGFSVLQVMATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHS 375
L G SV+QV ATD D G + Y + + + FS+D ++G L V + +DRE
Sbjct: 203 LSAGTSVIQVSATDADDPTYGNSARVVYSILEGQPYFSVDAKTGMLRV-SLADMDRETRE 261
Query: 376 SLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYY 435
+ + + AK+ + G A + + + N P+ + + G + +
Sbjct: 262 NYTVVIQAKDMGGQL-GGLAGTTTVNVMLTD-INDNPPMFDQS----KRAGARL-TARHR 314
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
QL + TL S LY+ S+ A VG+V+G++ A D D+G N +
Sbjct: 315 IAQLRASFQTYFTL-----------NSGLYQMSIPETAPVGSVVGRIWAKDRDIGINAEM 363
Query: 496 LYDLQRTSNLTITSPFKINPNT--GTVSVAESPILEGR--HALFVEASDQPANPS-ERRY 550
Y + T +P G ++V + E + + L VE ++ +P R
Sbjct: 364 KYSIIDGDGRD-TFDISTDPTNLFGIITVKKPLDFETKLSYTLKVEGANTHVDPHVHHRG 422
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND-VSYD 609
VTI ++P P F Y + + IGT V + D N+ V Y
Sbjct: 423 PFKDVTIVHVSVEDVDEP--PLFDSPAYLLELSEDAEIGTVVKTVSARDPDSANNTVRYS 480
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVD 668
+ + F ++ SG + V L R ++ +A++ N I + + V + D
Sbjct: 481 IERTSDLDKYFYIDITSGALMTVRTLDREEMSWHNITVLAMEMNNPSQIASASVAVKITD 540
Query: 669 VND 671
VND
Sbjct: 541 VND 543
Score = 60.9 bits (141), Expect = 3e-07
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 21/238 (8%)
Query: 987 EVKRYFVINERHGHVIVARSLPPESEFRLNISA--------LDGGNLNDNISVRVFVKDV 1038
E+K +++ + + + R L PESEF + I LDG + +++
Sbjct: 121 EMKAQYILRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQIGENM 180
Query: 1039 NDHFPVFKKTWYNFNVEEAQYTRRV---LGKVDATDAD---FGQNANLTYFIQPSDTDLP 1092
V K +++ + + +V ATDAD +G +A + Y I
Sbjct: 181 GQQASVVSKNCVKNDIQTRHFCLSAGTSVIQVSATDADDPTYGNSARVVYSILEGQPY-- 238
Query: 1093 FEISPLTGVLSVN-GELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F + TG+L V+ ++DRET + Y + + A+D G D+NDN P
Sbjct: 239 FSVDAKTGMLRVSLADMDRETRENYTVVIQAKDMGGQLGGLAGTTTVNVMLTDINDNPPM 298
Query: 1151 FYAFDEL---LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
F L +H A ++ + +Y+ +I E AP+G+ V +++A D D
Sbjct: 299 FDQSKRAGARLTARHRIAQLRASFQTYFTLNSGLYQMSIPETAPVGSVVGRIWAKDRD 356
Score = 52.8 bits (121), Expect = 7e-05
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D T+RY + +D K F +D +G+L + LD + + + + V
Sbjct: 465 VSARDPD-SANNTVRYSIERTSDLDKYFYIDITSGALMTVRTLDRE-----EMSWHNITV 518
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A ++NNP + A A V +++ D+NDN P + + EN G + V A D D+
Sbjct: 519 LAMEMNNPSQIASASVAVKITDVNDNPPSL-TQYLEAYVCENAKAGQLIQMVTALDVDEP 577
Query: 337 ENG-EFTYQL 345
+ G F+Y L
Sbjct: 578 QGGHRFSYSL 587
Score = 52.4 bits (120), Expect = 9e-05
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 22/174 (12%)
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
TF ID G ++ ++ DRE+K Y I+RA+ + + P LE +++
Sbjct: 102 TFTIDDSTGDIHAIQRLDREMKAQY--ILRAQARNRLTDRP----------LEPESEF-- 147
Query: 1365 KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVRADTDE 1424
+V+I+D+NDN P+F +G P +P + G + Q + + + T
Sbjct: 148 --IVKIQDINDNEPRFLDG--PYWATVPEMSQIGENMGQQASVVSKNCVKN---DIQTRH 200
Query: 1425 LVFFERLSLNGLTSPQATDSDIGINADIRYQILNEQAPRFAIDPVSGTVRVVAA 1478
S+ +++ A D G +A + Y IL Q P F++D +G +RV A
Sbjct: 201 FCLSAGTSVIQVSATDADDPTYGNSARVVYSILEGQ-PYFSVDAKTGMLRVSLA 253
Score = 50.4 bits (115), Expect = 4e-04
Identities = 62/210 (29%), Positives = 91/210 (43%), Gaps = 18/210 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLF--SLDSVN--GSLFLEKELDLDAE--HNLQANT 271
I A D+D+G+ A ++Y +I G+ R F S D N G + ++K LD + + + L+
Sbjct: 350 IWAKDRDIGINAEMKYSIIDGDGRDTFDISTDPTNLFGIITVKKPLDFETKLSYTLKVEG 409
Query: 272 FVLQVQAS-QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
V P K V + + D+ D P F+ Y + + E+ G V V A
Sbjct: 410 ANTHVDPHVHHRGPFKDVTI-VHVSVEDV-DEPPLFDSPAYLLELSEDAEIGTVVKTVSA 467
Query: 331 TDKDQGENGEFTYQLD---DPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKE- 385
D D N Y ++ D F ID SG L TVR LDRE S + V A E
Sbjct: 468 RDPDSA-NNTVRYSIERTSDLDKYFYIDITSGALMTVR---TLDREEMSWHNITVLAMEM 523
Query: 386 TNPSVVGTFADSQRIAKWRRQPLETNAPLE 415
NPS + + + + +I P LE
Sbjct: 524 NNPSQIASASVAVKITDVNDNPPSLTQYLE 553
Score = 47.2 bits (107), Expect = 0.003
Identities = 87/388 (22%), Positives = 157/388 (40%), Gaps = 33/388 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A + Y ++ G + FS+D+ G L + D+D E + + +QA
Sbjct: 217 ADDPTYGNSARVVYSILEG--QPYFSVDAKTGMLRVSLA-DMDRETR---ENYTVVIQAK 270
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ L V + L D+NDN P F+ + L + Q+ A+ +
Sbjct: 271 DMGGQLGGLAGTTTVNVMLTDINDNPPMFD---QSKRAGARLTARHRIAQLRASFQTYFT 327
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-LDREAHSSLRMKVYAKETNPSVVGTFAD 396
YQ+ P+ A + G + +++ + ++ E S+ + + + T
Sbjct: 328 LNSGLYQMSIPETA-PVGSVVGRIWAKDRDIGINAEMKYSI---IDGDGRDTFDISTDPT 383
Query: 397 SQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNN 456
+ ++PL+ L T V + T + ++ V V++ D D
Sbjct: 384 NLFGIITVKKPLDFETKLSYTLKV--EGANTHVDPHVHHRGPFKDVTIVHVSVEDV-DEP 440
Query: 457 PVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPN 516
P+F S Y + +A++GTV+ V A DPD N V Y ++RTS+L F I+
Sbjct: 441 PLF-DSPAYLLELSEDAEIGTVVKTVSARDPD-SANNTVRYSIERTSDL--DKYFYIDIT 496
Query: 517 TGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFM 574
+G + + E H + V A + NPS+ + A V +++T N P + ++
Sbjct: 497 SGALMTVRTLDREEMSWHNITVLAMEM-NNPSQ--IASASVAVKIT-DVNDNPPSLTQYL 552
Query: 575 GAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
E +V N G + + D E
Sbjct: 553 ----EAYVCENAKAGQLIQMVTALDVDE 576
Score = 42.7 bits (96), Expect = 0.075
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 12/126 (9%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGE----KAFIFLIAPIGPSL-TIPLTVPRGLT 139
V I+D+NDN P FLD PY TV E++ GE +A + + + T + G +
Sbjct: 149 VKIQDINDNEPRFLDGPYWATVPEMSQIGENMGQQASVVSKNCVKNDIQTRHFCLSAGTS 208
Query: 140 IFKDIRAFDRDKPNTPNS-DVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE-F 197
+ + + A D D P NS V YSI+ G +F++++ K +L + D D +E +
Sbjct: 209 VIQ-VSATDADDPTYGNSARVVYSILEGQP--YFSVDA--KTGMLRVSLADMDRETRENY 263
Query: 198 QLVIMA 203
+VI A
Sbjct: 264 TVVIQA 269
Score = 42.3 bits (95), Expect = 0.099
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 13/185 (7%)
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
+D D G + ++ Y + F I TG + LDRE + +YIL AR+
Sbjct: 81 SDMDKG-DGSIKYILTGEGAGTTFTIDDSTGDIHAIQRLDREMKAQYILRAQARNRLTDR 139
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE--SVMMIPVYKATIE 1187
D+NDN P+F D PE ++ + + SV+ K I+
Sbjct: 140 PLEPESEFIVKIQDINDNEPRF--LDGPYWATVPEMSQIGENMGQQASVVSKNCVKNDIQ 197
Query: 1188 EN---APIGTTVAKVFANDTDFIGNGNGL-ILYSLPQRKNQQNLGLPSLSSTAILMVTVA 1243
GT+V +V A D D GN ++YS+ + + ++ + T +L V++A
Sbjct: 198 TRHFCLSAGTSVIQVSATDADDPTYGNSARVVYSILEGQPYFSVD----AKTGMLRVSLA 253
Query: 1244 DVPDE 1248
D+ E
Sbjct: 254 DMDRE 258
>UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14942,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 630
Score = 94.7 bits (225), Expect = 2e-17
Identities = 64/190 (33%), Positives = 94/190 (49%), Gaps = 17/190 (8%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA-TYEG 794
G I+ Q+ LDRE+R V+R V+A ++G G V I + D NDN PVF A + G
Sbjct: 12 GKIYAQRTLDREERAVWRFVVLAT-DEGGEGLTGFTDVIINVWDINDNEPVFTCAPSCHG 70
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE-------------GKEMFDVDE 841
+ ENS +GT + D+ G NA+ Y + G EMF ++
Sbjct: 71 SVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPSSSEMFTINP 130
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSK 901
+TG + + LDRE+ Y + + ARD GGL+ A I I D ND+ P+F ++
Sbjct: 131 STGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIKDLNDHAPKFT--DDTCA 188
Query: 902 VRIHRETKLN 911
V+I T+ N
Sbjct: 189 VQISENTETN 198
Score = 62.9 bits (146), Expect = 7e-08
Identities = 51/196 (26%), Positives = 82/196 (41%), Gaps = 11/196 (5%)
Query: 940 IPENIPIGTTIIKLNALDLDS---GLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+ EN +GT+++++ A DLD G N + Y + + F IN
Sbjct: 72 VAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLD-GANFHDRGVPSSSEMFTINP 130
Query: 997 RHGHVIVA-RSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G + VA L E + + + A DGG L + + +KD+NDH P F
Sbjct: 131 STGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIKDLNDHAPKFTDDTCAVQ 190
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI----SPLTGVLSVNGELD 1109
+ E T + ++ A D D G+NA LT+ + D + F I G L + +LD
Sbjct: 191 ISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQEQRGTLRLKKKLD 250
Query: 1110 RETEDKYILTVVARDN 1125
E + + +DN
Sbjct: 251 YERHGEQRFNLTLKDN 266
Score = 59.7 bits (138), Expect = 6e-07
Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 24/181 (13%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK- 1046
F+I+E G + R+L E +R + A D G L V + V D+ND+ PVF
Sbjct: 5 FIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPVFTC 64
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPS-------DTDLP---- 1092
+ +V E + ++ ATD D GQNA L+Y I S D +P
Sbjct: 65 APSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPSSSE 124
Query: 1093 -FEISPLTGVLSVNGE-LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
F I+P TG +SV E LDRE + Y++ V ARD G D+ND++PK
Sbjct: 125 MFTINPSTGTISVAMEGLDREQVESYLIFVEARDGG---GLAGIATATIQIKDLNDHAPK 181
Query: 1151 F 1151
F
Sbjct: 182 F 182
Score = 56.4 bits (130), Expect = 6e-06
Identities = 75/296 (25%), Positives = 128/296 (43%), Gaps = 35/296 (11%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLL- 677
F ++E +G I L R R ++ F +A E L+ T+ ++V D+ND V
Sbjct: 5 FIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPVFTC 64
Query: 678 -KGAHSPIIFHVKENS-AGAAIGQIFHTNM--SSIYGNGTGNVRFLIANQQDVTDDIAIA 733
H V ENS G ++ ++ T++ S++ N + R + + D +
Sbjct: 65 APSCHGS----VAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVP 120
Query: 734 EDGTIFTQKP-----------LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+FT P LDRE+ + Y + V A G+ AGI TI I+D ND
Sbjct: 121 SSSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGL---AGIATATIQIKDLND 177
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV-- 839
+ P F T I EN++ E+ + A D D G NA +++ G+ ++ F +
Sbjct: 178 HAPKFTDDTCAVQISENTETNAEVLE---LAAEDRDIGENAQLTFSVVAGDQEQKFYIVS 234
Query: 840 --DENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEF 893
E G ++ + LD E+ + +L +D L+ A L + + + + EF
Sbjct: 235 HKQEQRGTLR-LKKKLDYERHGEQRFNLTLKD--NLNGTATLTALRTFDRERQKEF 287
Score = 53.2 bits (122), Expect = 5e-05
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 10/148 (6%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
++F+++ G++ + E LD E Q ++++ V+A A A ++I+ DLND
Sbjct: 124 EMFTINPSTGTISVAME-GLDRE---QVESYLIFVEARDGGGLAGIATATIQIK--DLND 177
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSI--DPR 357
+ P+F D + I EN VL++ A D+D GEN + T+ + D + F I +
Sbjct: 178 HAPKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQ 237
Query: 358 SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
T+R + LD E H R + K+
Sbjct: 238 EQRGTLRLKKKLDYERHGEQRFNLTLKD 265
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 15/119 (12%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD---LGQNG 493
E L F +V + + D NDN PVF + S+ N+ VGT + ++ A D D +GQN
Sbjct: 40 EGLTGFTDVIINVWDINDNEPVFTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNA 99
Query: 494 MVLYDLQRT---SNL------TITSPFKINPNTGTVSVAESPILEGR---HALFVEASD 540
++ Y + + +N + + F INP+TGT+SVA + + + +FVEA D
Sbjct: 100 VLSYRIMGSLDGANFHDRGVPSSSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARD 158
Score = 37.9 bits (84), Expect = 2.1
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 24/160 (15%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F +D V G ++ ++ LD + + + V A+ T V I + D+NDN
Sbjct: 5 FIIDEVTGKIYAQRTLDRE-----ERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNE 59
Query: 304 PEFE-VDFYNISIVENLPNGFSVLQVMATDKDQ---GENGEFTYQ----LDD-------- 347
P F + S+ EN G SV+++ ATD D G+N +Y+ LD
Sbjct: 60 PVFTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGV 119
Query: 348 PKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
P + F+I+P +G ++V + LDRE S + V A++
Sbjct: 120 PSSSEMFTINPSTGTISVAMEG-LDREQVESYLIFVEARD 158
>UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n=4;
Xenopus tropicalis|Rep: UPI000069E759 UniRef100 entry -
Xenopus tropicalis
Length = 818
Score = 94.3 bits (224), Expect = 2e-17
Identities = 129/461 (27%), Positives = 197/461 (42%), Gaps = 44/461 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
V + D NDN PVF+ SN++ ++ N+ V + + +++AVD D G+N ++ Y
Sbjct: 222 VQITDVNDNCPVFLTSNMF-IILQRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRVPAE 280
Query: 507 ITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
F + TG + +A +PI E H L V A P+ LA+ +
Sbjct: 281 SKKLFHLESMTGILRLA-APIPEDSPNNHKLTVLAIGPGCAPAVATVKLAIQEL------ 333
Query: 564 KGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG-YEEG-VPF 620
K +P + +GA E V + V + E D Y +L Y G +PF
Sbjct: 334 KRKEPRMEFRVIGAQGE----EGVSVKEDVPINTIIAILEIKDTDYSILRPVYINGTIPF 389
Query: 621 A--VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS--IVTNATVHVV--DVNDERG 674
A V E S ++ + + + + NA IV A+++V DVND
Sbjct: 390 ALKVSENSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLNVKLEDVNDNAP 449
Query: 675 VLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
S + V+EN S GA I ++ + S NG + F + D A
Sbjct: 450 QF---PQSVLEVSVEENNSPGAVILELSAFDRDS-GSNGIIDYSFGAELPMEFFID---A 502
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G + DRE++ Y + V+A + G + G V I I D+NDN P+F +
Sbjct: 503 SHGILTASVSFDREQKTSYTVIVLAS-DHGSPAQNGSCTVIITILDQNDNMPIFLTNEFT 561
Query: 794 GFIMEN-SKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
+ EN S+ GT II TDAD G N ++ F VD+N + +
Sbjct: 562 FSVPENLSRHGTV----GIINVTDADSGLNGEISLSMLNTTMP-FSVDKN---IILLEGY 613
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
LD E + Y+L + A D G LSS ++ IM+ D NDN P
Sbjct: 614 LDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAP 654
Score = 87.4 bits (207), Expect = 3e-15
Identities = 113/472 (23%), Positives = 205/472 (43%), Gaps = 53/472 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG-KVKAVDPDLGQNGMVLYDLQRTS 503
+++ +LD ND+ P F + S++ + VGT+ A DPD GQN ++LY L
Sbjct: 114 IKIFILDINDHAPFFT-DRIITISVQEDTAVGTIFSIDHSASDPDAGQNSILLYHLNSID 172
Query: 504 NLTITSPFKINPNTGTVSVA-ESPI-LEGRHALFVE--ASDQPANPSERRYSLAVVTIEV 559
N+ F + N+ +S+ + P+ E + +++ ASD+ P A++ +++
Sbjct: 173 NV-----FTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPPLS---GSALIIVQI 224
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
T + P F+ + + N + ++V Q+ D E + + + Y VP
Sbjct: 225 T----DVNDNCPVFLTSNMFIILQRNSSVNSTVTQLEAVD--EDTGENSIIQYVYSNRVP 278
Query: 620 ------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDE 672
F +E +G++ + + + + +A+ ++ T + + +
Sbjct: 279 AESKKLFHLESMTGILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKLAIQELKRKEP 338
Query: 673 R-GVLLKGAHSPIIFHVKEN---SAGAAIGQIFHTNMS---SIYGNGTGNVRFLIANQQD 725
R + GA VKE+ + AI +I T+ S +Y NGT + F + ++
Sbjct: 339 RMEFRVIGAQGEEGVSVKEDVPINTIIAILEIKDTDYSILRPVYINGT--IPFALKVSEN 396
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVI--AEFNKGVISGAGIYQVTIYIEDENDN 783
D + G LD E Y + V+ A F+ ++ A + + +ED NDN
Sbjct: 397 SPDTYLLLTSGI------LDFELEQKYTIQVLGNATFDNLIVYQASL---NVKLEDVNDN 447
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT 843
P F + E + EN+ G I + A D D G+N + Y+ E F +D +
Sbjct: 448 APQFPQSVLEVSVEENNSPGAVILE---LSAFDRDSGSNGIIDYSFGAELPMEFFIDASH 504
Query: 844 GVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
G++ S DRE+K Y + ++A D G + +II I D+NDN P F
Sbjct: 505 GILT-ASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIF 555
Score = 79.4 bits (187), Expect = 7e-13
Identities = 62/214 (28%), Positives = 101/214 (47%), Gaps = 23/214 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G I++L+A D DSG NG I Y F +E+ P + F I+ HG
Sbjct: 460 VEENNSPGAVILELSAFDRDSGSNGIIDYSFGAEL---PME-----------FFIDASHG 505
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + S E + + + + A D G+ N + +V + + D ND+ P+F + F+V
Sbjct: 506 ILTASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVP 565
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E +G ++ TDAD G N ++ + +T +PF + ++ + G LD E+E K
Sbjct: 566 ENLSRHGTVGIINVTDADSGLNGEIS--LSMLNTTMPFSVD--KNIILLEGYLDYESEYK 621
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
Y L + A D G D+NDN+P
Sbjct: 622 YELWIEAHDKG-NPPLSSTVKVNIMVLDMNDNAP 654
Score = 67.3 bits (157), Expect = 3e-09
Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 8/147 (5%)
Query: 770 IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
I ++ I+I D ND+ P F + E++ +GT +D+ A+D D G N++ +Y L
Sbjct: 111 IAKIKIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDH--SASDPDAGQNSILLYHL 168
Query: 830 FGEGKEMFDVDENTGVVKF-IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE 886
+F + N+ ++ + LD E K Y + L+A D G LS A +I+ I D
Sbjct: 169 -NSIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGSALIIVQITDV 227
Query: 887 NDNKPEFNQIEENSKVRIHRETKLNGT 913
NDN P F + N + + R + +N T
Sbjct: 228 NDNCPVF--LTSNMFIILQRNSSVNST 252
Score = 62.9 bits (146), Expect = 7e-08
Identities = 64/248 (25%), Positives = 113/248 (45%), Gaps = 22/248 (8%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+D ++ ++ V L D NDN P F P ++ E S++ N G VI ++ A D D G NG+
Sbjct: 427 FDNLIVYQASLNVKLEDVNDNAPQF-PQSVLEVSVEENNSPGAVILELSAFDRDSGSNGI 485
Query: 495 VLYDLQRTSNLTITSPFKINPNTG--TVSVAESPILEGRHALFVEASDQPANPSERRYSL 552
+ Y + F I+ + G T SV+ + + + V ASD +P++
Sbjct: 486 IDYSF----GAELPMEFFIDASHGILTASVSFDREQKTSYTVIVLASDH-GSPAQNGSCT 540
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
++TI ++P F+ + F V N+ +VG I V DA ++S +
Sbjct: 541 VIITI------LDQNDNMPIFLTNEFTFSVPENLSRHGTVGIINVTDADSGLNGEISLSM 594
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDV 669
L+ +PF+V++ +I + L + Y+ A + N LS + V+D+
Sbjct: 595 LN---TTMPFSVDK--NIILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDM 649
Query: 670 NDERGVLL 677
ND ++L
Sbjct: 650 NDNAPLIL 657
Score = 62.5 bits (145), Expect = 9e-08
Identities = 93/426 (21%), Positives = 176/426 (41%), Gaps = 32/426 (7%)
Query: 927 FALDVDQLGPLFL-------IPENIPIGTTI-IKLNALDLDSGLNGQIRYEFNSEVYIPP 978
F LD++ P F + E+ +GT I +A D D+G N + Y NS +
Sbjct: 117 FILDINDHAPFFTDRIITISVQEDTAVGTIFSIDHSASDPDAGQNSILLYHLNSIDNVFT 176
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVK 1036
++ L + + + H +SE+ +++ A D G L+ + + V +
Sbjct: 177 LGNNSQLLSL----TLQQPLDH-------ESKSEYYMDLIASDKGQPPLSGSALIIVQIT 225
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPF 1093
DVND+ PVF + ++ + +++A D D G+N+ + Y P+++ F
Sbjct: 226 DVNDNCPVFLTSNMFIILQRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRVPAESKKLF 285
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYA 1153
+ +TG+L + + ++ + + LTV+A G + +F
Sbjct: 286 HLESMTGILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKLAIQELKR-KEPRMEFRV 344
Query: 1154 FDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV---AKVFANDTD-FIGN 1209
E +++ + +++ I +I I T+ KV N D ++
Sbjct: 345 IGAQGEEGVSVKEDVPINTIIAILEIKDTDYSILRPVYINGTIPFALKVSENSPDTYLLL 404
Query: 1210 GNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN 1269
+G++ + L Q+ Q LG + + + ++ +V E + P F E+ +EEN
Sbjct: 405 TSGILDFELEQKYTIQVLGNATFDNLIVYQASL-NVKLEDVNDNAPQFPQSVLEVSVEEN 463
Query: 1270 VNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTY 1329
N+P ++ L L+ + I ++ F ID +G L S DRE K +Y
Sbjct: 464 -NSPGAVI-LELSAFDRDSGSNGIIDYSFGAELPMEFFIDASHGILTASVSFDREQKTSY 521
Query: 1330 EVIVRA 1335
VIV A
Sbjct: 522 TVIVLA 527
Score = 58.0 bits (134), Expect = 2e-06
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D+D G + Y + + F +D+ +G L + D E Q ++ + V
Sbjct: 473 LSAFDRDSGSNGIIDYSFGAELPMEFF-IDASHG--ILTASVSFDRE---QKTSYTVIVL 526
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
AS +P + V I +LD NDN+P F + + S+ ENL +V + TD D G
Sbjct: 527 ASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVPENLSRHGTVGIINVTDADSGL 586
Query: 338 NGEFTYQLDDPKGAFSID 355
NGE + + + FS+D
Sbjct: 587 NGEISLSMLNTTMPFSVD 604
Score = 56.4 bits (130), Expect = 6e-06
Identities = 79/325 (24%), Positives = 127/325 (39%), Gaps = 15/325 (4%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
S+ V ++DVND+ P F ++ +VEE V+ ++ A D D G N + Y ++
Sbjct: 436 SLNVKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSF-GAEL 494
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ F I G+L+ + DRE + Y + V+A D+G D NDN P
Sbjct: 495 PMEFFIDASHGILTASVSFDREQKTSYTVIVLASDHG-SPAQNGSCTVIITILDQNDNMP 553
Query: 1150 KFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKV---FANDTDF 1206
F E+ + LS H +V +I V A N I ++ F+ D +
Sbjct: 554 IFLT----NEFTFSVPENLSRHG--TVGIINVTDADSGLNGEISLSMLNTTMPFSVDKNI 607
Query: 1207 I---GNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
I G + Y + G P LSST + + V D+ D + P Y
Sbjct: 608 ILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVL 667
Query: 1264 LEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+ + + V V + N ++Y E + F ID G + L S
Sbjct: 668 VPPDTLKGSSVTKVHAVDYDAGMNGAIQYSGFGELG-PLGDLFTIDNITGNITLKESIIG 726
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMI 1348
Y+ +V+A Q Y L ++
Sbjct: 727 HHCGLYQFMVKASDQGYPEALSTIV 751
Score = 56.0 bits (129), Expect = 7e-06
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ +QV + + L QA + ++L D+NDN P+F +S+ EN G +L++ A
Sbjct: 417 YTIQVLGNATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAF 476
Query: 332 DKDQGENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D+D G NG Y + F ID G LT DRE +S + V A +
Sbjct: 477 DRDSGSNGIIDYSFGAELPMEFFIDASHGILTA--SVSFDREQKTSYTVIVLASD 529
Score = 55.6 bits (128), Expect = 1e-05
Identities = 81/315 (25%), Positives = 129/315 (40%), Gaps = 39/315 (12%)
Query: 75 NQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE-----KAFI-------FLIA 122
N I S+ V +EDVNDN P F + V+V+E G AF +
Sbjct: 429 NLIVYQASLNVKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDY 488
Query: 123 PIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
G L + + I +FDR++ + + IV +D G A S ++
Sbjct: 489 SFGAELPMEFFIDASHGILTASVSFDREQKTS-----YTVIVLASDHGSPAQNGSCTVII 543
Query: 183 LLRKVLDYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND 240
+ D EF + + R H + I+ D D G+ + ++ N
Sbjct: 544 TILDQNDNMPIFLTNEFTFSVPENLSR-HGTVGI---INVTDADSGLNGEISLSML--NT 597
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
FS+D + LE LD ++E+ + L ++A NP ++ +V I +LD+N
Sbjct: 598 TMPFSVDK--NIILLEGYLDYESEYKYE-----LWIEAHDKGNPPLSSTVKVNIMVLDMN 650
Query: 301 DNLPEFEVDFYNISIVENLPN---GFSVLQVMATDKDQGENGEFTY----QLDDPKGAFS 353
DN P + N S V P+ G SV +V A D D G NG Y +L F+
Sbjct: 651 DNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFT 710
Query: 354 IDPRSGWLTVRNQTV 368
ID +G +T++ +
Sbjct: 711 IDNITGNITLKESII 725
Score = 54.4 bits (125), Expect = 2e-05
Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 2/122 (1%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLG-KVDATDADFGQNANLTYFIQPSDT 1089
+++F+ D+NDH P F +V+E + A+D D GQN+ L Y + D
Sbjct: 114 IKIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDHSASDPDAGQNSILLYHLNSIDN 173
Query: 1090 DLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ L++ LD E++ +Y + ++A D G DVNDN P
Sbjct: 174 VFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKG-QPPLSGSALIIVQITDVNDNCP 232
Query: 1150 KF 1151
F
Sbjct: 233 VF 234
Score = 52.0 bits (119), Expect = 1e-04
Identities = 42/147 (28%), Positives = 70/147 (47%), Gaps = 8/147 (5%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTF---VLQVQASQLNNPLKTAQARVEIELLDLN 300
F LD G L+ LD EH +T +++ A +++ + A+++I +LD+N
Sbjct: 65 FHLDKQTGDLYTTA-FKLDREHLCPQDTLNQCFVEIDAF-VSSQEHSEIAKIKIFILDIN 122
Query: 301 DNLPEFEVDFYNISIVENLPNG--FSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRS 358
D+ P F IS+ E+ G FS+ A+D D G+N Y L+ F++ S
Sbjct: 123 DHAPFFTDRIITISVQEDTAVGTIFSI-DHSASDPDAGQNSILLYHLNSIDNVFTLGNNS 181
Query: 359 GWLTVRNQTVLDREAHSSLRMKVYAKE 385
L++ Q LD E+ S M + A +
Sbjct: 182 QLLSLTLQQPLDHESKSEYYMDLIASD 208
Score = 49.6 bits (113), Expect = 6e-04
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 27/233 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +T+LD NDN P+F+ +N + FS+ N +G + D D G NG + S
Sbjct: 541 VIITILDQNDNMPIFL-TNEFTFSVPENLSRHGTVGIINVTDADSGLNGEI-----SLSM 594
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
L T PF ++ N + E ++ L++EA D+ P + ++ +++
Sbjct: 595 LNTTMPFSVDKNIILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDM----N 650
Query: 565 GNKPDI--PD----FMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE-- 616
N P I PD ++ P + GS+V T V + DA + Y G+ E
Sbjct: 651 DNAPLILLPDSNFSYVLVPPDTLKGSSV---TKVHAVDY-DAGMNGAIQYS---GFGELG 703
Query: 617 --GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
G F ++ +G IT+ + + ++ +Y F A + ++ T ++++
Sbjct: 704 PLGDLFTIDNITGNITLKESIIGHHCGLYQFMVKASDQGYPEALSTIVRINIL 756
Score = 48.0 bits (109), Expect = 0.002
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D G + L Y L S ++ +F+L N S L L +H ++ + + + AS
Sbjct: 153 ASDPDAGQNSILLYHLNSIDN--VFTLG--NNSQLLSLTLQQPLDHESKSE-YYMDLIAS 207
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P + A + +++ D+NDN P F I + N +V Q+ A D+D GEN
Sbjct: 208 DKGQPPLSGSALIIVQITDVNDNCPVFLTSNMFIILQRNSSVNSTVTQLEAVDEDTGENS 267
Query: 340 EFTY 343
Y
Sbjct: 268 IIQY 271
Score = 46.8 bits (106), Expect = 0.005
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 5/107 (4%)
Query: 439 LMSFVNVEVTLLDANDNNP-VFVPSNLYEFSM-KSNAKVGTVIGKVKAVDPDLGQNGMVL 496
L S V V + +LD NDN P + +P + + + + + G+ + KV AVD D G NG +
Sbjct: 636 LSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQ 695
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQ 541
Y + F I+ TG +++ ES I G + V+ASDQ
Sbjct: 696 YSGFGELG-PLGDLFTIDNITGNITLKESIIGHHCGLYQFMVKASDQ 741
Score = 46.0 bits (104), Expect = 0.008
Identities = 55/198 (27%), Positives = 83/198 (41%), Gaps = 26/198 (13%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F +PEN+ T+ +N D DSGLNG+I S L F +++
Sbjct: 562 FSVPENLSRHGTVGIINVTDADSGLNGEI---------------SLSMLNTTMPFSVDKN 606
Query: 998 HGHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+++ L ESE++ L I A D GN L+ + V + V D+ND+ P+ NF+
Sbjct: 607 I--ILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFS 664
Query: 1054 ---VEEAQYTRRVLGKVDATDADFGQNANLTY--FIQPSDTDLPFEISPLTGVLSVNGEL 1108
V + KV A D D G N + Y F + F I +TG +++ +
Sbjct: 665 YVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESI 724
Query: 1109 DRETEDKYILTVVARDNG 1126
Y V A D G
Sbjct: 725 IGHHCGLYQFMVKASDQG 742
Score = 43.2 bits (97), Expect = 0.056
Identities = 73/331 (22%), Positives = 129/331 (38%), Gaps = 26/331 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVIT 630
P F + E V N G + ++ D ++ D G E + F ++ G++T
Sbjct: 449 PQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSFGAELPMEFFIDASHGILT 508
Query: 631 VVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPIIFHVK 689
R + Y +A + + + ++D ND + L + F V
Sbjct: 509 ASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFT---FSVP 565
Query: 690 EN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
EN S +G I T+ S NG ++ L D I +G LD E
Sbjct: 566 ENLSRHGTVGIINVTDADSGL-NGEISLSMLNTTMPFSVDKNIILLEGY------LDYES 618
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF--EHATYEGFIMENSKI-GTE 805
Y + + A +KG + +V I + D NDN P+ + + ++ + G+
Sbjct: 619 EYKYELWIEAH-DKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVPPDTLKGSS 677
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGE-GK--EMFDVDENTGVVKFIGDSLDREKKIMYK 862
+ + A D D G N Y+ FGE G ++F +D TG + + +S+ +Y+
Sbjct: 678 VTK---VHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNIT-LKESIIGHHCGLYQ 733
Query: 863 LSLVARDTG---GLSSEAELIIMIGDENDNK 890
+ A D G LS+ + I++ N+
Sbjct: 734 FMVKASDQGYPEALSTIVRINILLNHSISNR 764
>UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 471
Score = 94.3 bits (224), Expect = 2e-17
Identities = 111/459 (24%), Positives = 196/459 (42%), Gaps = 39/459 (8%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNA-------KVGT-VI 479
K +++ D + + V V V +LD+NDN PVF + Y M ++ KVG V+
Sbjct: 24 KATDVDPVDPRWSAAV-VYVEVLDSNDNAPVFKKQS-YVVEMVEHSPTTFTVVKVGEKVV 81
Query: 480 GKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNT--GTVSVAESPILEGRHALFVE 537
+K D D+G NG + Y + + + F I+ ++ V++ + ++L V
Sbjct: 82 FLIKTTDRDVGSNGRISYSIVSGN---VDGAFVIDSSSVIRVVALVDREAHPAGYSLLVV 138
Query: 538 ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV 597
A D P+ + A + +T + + P F+ Y V + +GT V Q++
Sbjct: 139 ARDH-GYPTP---NAATARVNITISDIND--NAPRFLKFTYSGSVREDRTVGTEVVQVQA 192
Query: 598 NDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
D + ++ + + G EG+ F++ SG ITV L R + Y+ A +
Sbjct: 193 TDDDDGLAGEIVFAITGGDPEGL-FSILNTSGKITVARSLDREMKATYELTVTATDRAGD 251
Query: 656 -LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGT 713
S + + D ND + V + P + E++ G + + T+
Sbjct: 252 PKSTSVEVDITITDANDNKPVF---TNIPATILLSESTIPGTPVITVVATDQDI---GVN 305
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
G VR++ + + AI G + T LD E Y + ++A + +
Sbjct: 306 GQVRYVGDSPKGKFAVNAIT--GVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHL 363
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGE 832
I + D NDN P F A Y + E + GT + M + AT+ D G ++ Y + G+
Sbjct: 364 NISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIM---VNATERDSGKDSKITYNISAGD 420
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+ F ++ TG + + +LDRE +Y L + ARD G
Sbjct: 421 PLDHFAINHLTGQIS-VRKALDRETTSLYTLLVSARDGG 458
Score = 89.4 bits (212), Expect = 7e-16
Identities = 79/267 (29%), Positives = 117/267 (43%), Gaps = 23/267 (8%)
Query: 664 VHVVDVNDERGVLLKGA-------HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
V V+D ND V K + HSP F V + G + + T + NG +
Sbjct: 42 VEVLDSNDNAPVFKKQSYVVEMVEHSPTTFTVVK--VGEKVVFLIKTTDRDVGSNGRISY 99
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTI 775
+ N V I I +DRE Y + V+A + A +V I
Sbjct: 100 SIVSGN---VDGAFVIDSSSVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNI 156
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
I D NDN P F TY G + E+ +GTE+ ++ATD D+G ++ + G E
Sbjct: 157 TISDINDNAPRFLKFTYSGSVREDRTVGTEVVQ---VQATDDDDGLAGEIVFAITGGDPE 213
Query: 836 -MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
+F + +G + + SLDRE K Y+L++ A D G S+ E+ I I D NDNKP
Sbjct: 214 GLFSILNTSGKIT-VARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPV 272
Query: 893 FNQIEENSKVRIHRETKLNGTAGFTII 919
F I + E+ + GT T++
Sbjct: 273 FTNIPATI---LLSESTIPGTPVITVV 296
Score = 81.8 bits (193), Expect = 1e-13
Identities = 106/380 (27%), Positives = 157/380 (41%), Gaps = 35/380 (9%)
Query: 532 HALFVEASDQPANPSERRYSLAVVTIEVTRGT------KGNKPDIPDFMGAPYEFWVGSN 585
+ L V+A+D +P + R+S AVV +EV K + +P F V
Sbjct: 19 YTLDVKATD--VDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPTTFTV--- 73
Query: 586 VGIGTSVG---QIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
V +G V + D +SY ++ G +G F ++ S VI VV + R P
Sbjct: 74 VKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGA-FVIDS-SSVIRVVALVDREAHPA 131
Query: 643 -YDFEAVALQENANLSIVTNATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
Y VA A V++ D+ND LK +S + ++ + G + Q
Sbjct: 132 GYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVR--EDRTVGTEVVQ 189
Query: 700 IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE 759
+ T+ G + F I + G I + LDRE + Y +TV A
Sbjct: 190 VQATDDDD---GLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTAT 246
Query: 760 FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
G + +V I I D NDN PVF + + E++ GT + + ATD D
Sbjct: 247 DRAGDPKSTSV-EVDITITDANDNKPVFTNIPATILLSESTIPGTPVIT---VVATDQDI 302
Query: 820 GTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGL---SS 875
G N Y G+ K F V+ TGVV +G+ LD E Y + +VA D G S+
Sbjct: 303 GVNGQVRYV--GDSPKGKFAVNAITGVVSTVGE-LDYEDVQRYTVYIVATDQGEPQLNST 359
Query: 876 EAELIIMIGDENDNKPEFNQ 895
L I + D NDN P F +
Sbjct: 360 TLHLNISLVDANDNNPTFTK 379
Score = 80.2 bits (189), Expect = 4e-13
Identities = 66/193 (34%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
L+ E+ GT +I + A D D G+NGQ+RY +S P K F +N
Sbjct: 281 LLSESTIPGTPVITVVATDQDIGVNGQVRYVGDS----PKGK-----------FAVNAIT 325
Query: 999 GHVIVARSLPPE--SEFRLNISALDGG--NLND-NISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V L E + + I A D G LN + + + + D ND+ P F K Y +
Sbjct: 326 GVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAH 385
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
V E + V+AT+ D G+++ +TY I D F I+ LTG +SV LDRET
Sbjct: 386 VSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDHFAINHLTGQISVRKALDRETT 445
Query: 1114 DKYILTVVARDNG 1126
Y L V ARD G
Sbjct: 446 SLYTLLVSARDGG 458
Score = 79.4 bits (187), Expect = 7e-13
Identities = 63/216 (29%), Positives = 96/216 (44%), Gaps = 19/216 (8%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ +GT ++++ A D D GL G+I + P L F I G
Sbjct: 177 VREDRTVGTEVVQVQATDDDDGLAGEIVFAITGG---DPEGL----------FSILNTSG 223
Query: 1000 HVIVARSLPPESE--FRLNISALD--GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ VARSL E + + L ++A D G + ++ V + + D ND+ PVF +
Sbjct: 224 KITVARSLDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLS 283
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E+ + V ATD D G N + Y + S F ++ +TGV+S GELD E +
Sbjct: 284 ESTIPGTPVITVVATDQDIGVNGQVRY-VGDSPKG-KFAVNAITGVVSTVGELDYEDVQR 341
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y + +VA D G D NDN+P F
Sbjct: 342 YTVYIVATDQGEPQLNSTTLHLNISLVDANDNNPTF 377
Score = 78.6 bits (185), Expect = 1e-12
Identities = 130/510 (25%), Positives = 197/510 (38%), Gaps = 74/510 (14%)
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLS---SEAELIIMIGDENDNKPEFNQIEEN 899
TG ++ +G LDRE K+ Y L + A D + S A + + + D NDN P F +
Sbjct: 2 TGDIRAVG-LLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60
Query: 900 SKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLD 959
++ H T FT+++V K +FLI TT D D
Sbjct: 61 VEMVEHSPTT------FTVVKVGEK-----------VVFLIK------TT-------DRD 90
Query: 960 SGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISA 1019
G NG+I Y S D+ V R + +R H + + L + A
Sbjct: 91 VGSNGRISYSIVSGNV--DGAFVIDSSSVIRVVALVDREAH---------PAGYSLLVVA 139
Query: 1020 LDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ 1076
D G N + V + + D+ND+ P F K Y+ +V E + + +V ATD D G
Sbjct: 140 RDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTEVVQVQATDDDDGL 199
Query: 1077 NANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXX 1136
+ + I D + F I +G ++V LDRE + Y LTV A D
Sbjct: 200 AGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTATDR-AGDPKSTSVE 258
Query: 1137 XXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA--TIEENAP--- 1191
D NDN P F P LS +I V I N
Sbjct: 259 VDITITDANDNKPVFTNI--------PATILLSESTIPGTPVITVVATDQDIGVNGQVRY 310
Query: 1192 IGTTVAKVFA-NDTDFIGNGNGLILYSLPQRKN----QQNLGLPSLSSTAI-LMVTVADV 1245
+G + FA N + + G + Y QR + G P L+ST + L +++ D
Sbjct: 311 VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVDA 370
Query: 1246 PDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRT 1305
D + P F Y + E A ++ +N TE ++ K N + D
Sbjct: 371 ND-----NNPTFTKAAYTAHVSEEATAGTNVIMVNATER-DSGKDSKITYNISAGDPLDH 424
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
F I+ G + + ++ DRE Y ++V A
Sbjct: 425 FAINHLTGQISVRKALDRETTSLYTLLVSA 454
Score = 77.8 bits (183), Expect = 2e-12
Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I D+D+G + Y ++SGN F +DS S + +D E + + ++ +
Sbjct: 84 IKTTDRDVGSNGRISYSIVSGNVDGAFVIDS---SSVIRVVALVDREAHPAGYSLLVVAR 140
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
P A ARV I + D+NDN P F Y+ S+ E+ G V+QV ATD D G
Sbjct: 141 DHGYPTP-NAATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTEVVQVQATDDDDGL 199
Query: 338 NGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET--NPSVVGT 393
GE + + DP+G FSI SG +TV LDRE ++ + V A + +P
Sbjct: 200 AGEIVFAITGGDPEGLFSILNTSGKITVARS--LDREMKATYELTVTATDRAGDPKSTSV 257
Query: 394 FADSQRIAKWRRQPLETNAP 413
D +P+ TN P
Sbjct: 258 EVDITITDANDNKPVFTNIP 277
Score = 75.4 bits (177), Expect = 1e-11
Identities = 51/168 (30%), Positives = 86/168 (51%), Gaps = 10/168 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A DQD+GV +RY + + + F+++++ G + ELD + ++Q T + V
Sbjct: 297 ATDQDIGVNGQVRY--VGDSPKGKFAVNAITGVVSTVGELDYE---DVQRYTVYI-VATD 350
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
Q L + + I L+D NDN P F Y + E G +V+ V AT++D G++
Sbjct: 351 QGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDS 410
Query: 340 EFTYQLD--DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ TY + DP F+I+ +G ++VR LDRE S + V A++
Sbjct: 411 KITYNISAGDPLDHFAINHLTGQISVRK--ALDRETTSLYTLLVSARD 456
Score = 72.1 bits (169), Expect = 1e-10
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D D G+ + + + G+ LFS+ + +G + + + LD + + T+ L V
Sbjct: 190 VQATDDDDGLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKA-----TYELTVT 244
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A+ K+ V+I + D NDN P F I + E+ G V+ V+ATD+D G
Sbjct: 245 ATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGV 304
Query: 338 NGEFTYQLDDPKGAFSIDPRSG 359
NG+ Y D PKG F+++ +G
Sbjct: 305 NGQVRYVGDSPKGKFAVNAITG 326
Score = 58.0 bits (134), Expect = 2e-06
Identities = 44/126 (34%), Positives = 68/126 (53%), Gaps = 19/126 (15%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPL--KTAQARVEIELLDLNDNLPEFEVDFYNISIVEN 318
LD E L + L V+A+ ++ P+ + + A V +E+LD NDN P F+ Y + +VE+
Sbjct: 11 LDRETKLN---YTLDVKATDVD-PVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEH 66
Query: 319 LPNGFSVLQV--------MATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTV 368
P F+V++V TD+D G NG +Y + + GAF ID S +R +
Sbjct: 67 SPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDSSS---VIRVVAL 123
Query: 369 LDREAH 374
+DREAH
Sbjct: 124 VDREAH 129
Score = 44.8 bits (101), Expect = 0.018
Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 23/124 (18%)
Query: 82 SVTVYIE--DVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLT 139
+ VY+E D NDN P+F Y V + E +PT F + +G +
Sbjct: 37 AAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPT-----TFTVVKVGEKV----------- 80
Query: 140 IFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL 199
+F I+ DRD + N + YSIVSGN DG F ++SS V+ + ++D +A + L
Sbjct: 81 VFL-IKTTDRDVGS--NGRISYSIVSGNVDGAFVIDSS--SVIRVVALVDREAHPAGYSL 135
Query: 200 VIMA 203
+++A
Sbjct: 136 LVVA 139
>UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 550
Score = 94.3 bits (224), Expect = 2e-17
Identities = 62/180 (34%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS-----LFLEKELDLDAEHNLQANTFVL 274
A+D D+G + Y ++ GN+ LFSL S ++L LD E + + L
Sbjct: 151 ALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETR---DFYQL 207
Query: 275 QVQASQLNNPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
+ A PL ++ + V I +LD ND+ PEF DFY S+ EN PNG +L+V A D+
Sbjct: 208 VIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQ 267
Query: 334 DQGENGEFTYQLDD--PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
D G+NGE + LD+ +G F +D +G + VLD E S R+ V A++ P +
Sbjct: 268 DIGKNGEIMFYLDESPERGLFRMDEYTG--EIWTNAVLDYEVKSEYRLTVVAQDQGPDSI 325
Score = 77.0 bits (181), Expect = 4e-12
Identities = 54/152 (35%), Positives = 77/152 (50%), Gaps = 7/152 (4%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
K LDRE RD Y++ ++A + +G +V I I D ND+ P F Y + EN+
Sbjct: 195 KRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAP 254
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENTGVVKFIGDSLDREKKI 859
GT + + A D D G N M+ L E E +F +DE TG + + LD E K
Sbjct: 255 NGTYLLR---VTAIDQDIGKNGEIMFYL-DESPERGLFRMDEYTGEI-WTNAVLDYEVKS 309
Query: 860 MYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
Y+L++VA+D G S + I D+NDN P
Sbjct: 310 EYRLTVVAQDQGPDSIPVRAQVTIKDKNDNAP 341
Score = 71.3 bits (167), Expect = 2e-10
Identities = 65/229 (28%), Positives = 101/229 (44%), Gaps = 18/229 (7%)
Query: 926 KFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA 985
KF D ++L I E+ P + ALD D G N Y + ++ +
Sbjct: 126 KFPQDFEELQ----ISESAPERSKFPLQRALDADIGNNSIQEYRI-----VRGNEDGLFS 176
Query: 986 LEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG---NLNDNISVRVFVKDVND 1040
L +KR F + + +++ + L E+ ++L I A+DGG + V + + D ND
Sbjct: 177 LSLKR-FSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSND 235
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG 1100
H P F K +Y +V E L +V A D D G+N + +++ S F + TG
Sbjct: 236 HSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERGLFRMDEYTG 295
Query: 1101 VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ N LD E + +Y LTVVA+D G D NDN+P
Sbjct: 296 EIWTNAVLDYEVKSEYRLTVVAQDQG---PDSIPVRAQVTIKDKNDNAP 341
Score = 70.1 bits (164), Expect = 4e-10
Identities = 107/459 (23%), Positives = 194/459 (42%), Gaps = 39/459 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+ EV +LD ND++P F P + E + +A + +A+D D+G N + Y + R
Sbjct: 111 IPTEVRVLDINDHSPKF-PQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRG 169
Query: 503 SN--LTITSPFKINPNTGTVSVAESPILEGR----HALFVEASDQ--PANPSERRYSLAV 554
+ L S + +P+ V + + L+ + L + A D P S R+
Sbjct: 170 NEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRK----- 224
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH 612
EV + P+F Y V N GT + ++ D + ++ + L
Sbjct: 225 ---EVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDE 281
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
E G+ F ++E +G I L + Y VA Q+ SI A V + D ND
Sbjct: 282 SPERGL-FRMDEYTGEIWTNAVLDYEVKSEYRLTVVA-QDQGPDSIPVRAQVTIKDKNDN 339
Query: 673 RGVLL-------KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
+ A ++ + AI ++ + SS+ N +V L+ ++ D
Sbjct: 340 APTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRD-SSLTVNSVVDVT-LLHHKHD 397
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ Q+PL+ ++ +Y++ IA ++GV + +T++IED+N + P
Sbjct: 398 FALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIAR-DRGVPTLETNNSLTLHIEDKNRHTP 456
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENTG 844
+ + + I++N++ G E+ I+ATD D G N Y+L G + F +D++ G
Sbjct: 457 TYPTPSRDITIIDNTQPGDEVV---TIRATDPDSGLNGKIQYSLIAGNDDKTFILDKDRG 513
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
+ Y L++ A D+G SE+ + I I
Sbjct: 514 ELVVFNYMFQSS----YVLTIKASDSGNPPSESLVRIRI 548
Score = 63.7 bits (148), Expect = 4e-08
Identities = 50/156 (32%), Positives = 69/156 (44%), Gaps = 11/156 (7%)
Query: 1007 LPPESE---FRLNISAL-DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
LPP ++ F++ I D G ++ I V V D+NDH P F + + + E+ R
Sbjct: 85 LPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAPERS 144
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEIS------PLTGVLSVNGE-LDRETEDK 1115
A DAD G N+ Y I + D F +S + V VN + LDRET D
Sbjct: 145 KFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDF 204
Query: 1116 YILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
Y L +VA D G D ND+SP+F
Sbjct: 205 YQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEF 240
Score = 54.8 bits (126), Expect = 2e-05
Identities = 65/231 (28%), Positives = 99/231 (42%), Gaps = 19/231 (8%)
Query: 680 AHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
A + + F VKE GA +G + T++ G +R+ I D +I A G +
Sbjct: 16 AANSLRFQVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGPADGIFEINAAT-GVL 74
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE----DENDNPPVFEHATYEG 794
T+ L+REK I + V + G TI E D ND+ P F E
Sbjct: 75 RTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEEL 134
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD------ENTGVVK 847
I E++ ++ + +A DAD G N++ Y + G +F + + V
Sbjct: 135 QISESAPERSKFPLQ---RALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYL 191
Query: 848 FIGDSLDREKKIMYKLSLVARDTG---GLSSEAELIIMIGDENDNKPEFNQ 895
LDRE + Y+L +VA D G S E+ I I D ND+ PEF++
Sbjct: 192 VNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSK 242
Score = 47.2 bits (107), Expect = 0.003
Identities = 47/169 (27%), Positives = 81/169 (47%), Gaps = 16/169 (9%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE------- 788
G I+T LD E + YR+TV+A+ ++G S QVT I+D+NDN P +
Sbjct: 295 GEIWTNAVLDYEVKSEYRLTVVAQ-DQGPDSIPVRAQVT--IKDKNDNAPTIQVKLLQVP 351
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE--NTGVV 846
+A G + E+ G+ + + ++ D+ N++ TL K F + NT
Sbjct: 352 NAARPGLVPEDITTGSNVAIVE-VRDRDSSLTVNSVVDVTLL-HHKHDFALRRIFNTFYN 409
Query: 847 KFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
+ L+ ++ +YK+ +ARD G L + L + I D+N + P +
Sbjct: 410 LEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDKNRHTPTY 458
Score = 46.0 bits (104), Expect = 0.008
Identities = 67/289 (23%), Positives = 112/289 (38%), Gaps = 30/289 (10%)
Query: 68 VRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFI--FLIAPIG 125
+++ +SA + V + D+ND+ P F + + E P K + L A IG
Sbjct: 98 IKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIG 157
Query: 126 PSLTIPLTVPRGLT--IFK-DIRAFDRDK-----PNTPNSDVH----YSIVSGNDDGHFA 173
+ + RG +F ++ F D NT D Y +V DG F
Sbjct: 158 NNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFP 217
Query: 174 LESSHKPVLLLRKVLDYDAGDKEFQL-VIMASGKRIHKEILFPEPIHAIDQDLGVGATLR 232
L S + + + +LD + EF AS + + AIDQD+G +
Sbjct: 218 LPRSGRKEVNIT-ILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIM 276
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+ L +R LF +D G ++ LD + + + T V Q Q + R
Sbjct: 277 FYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRL-TVVAQDQGPD------SIPVRA 329
Query: 293 EIELLDLNDNLPEFEVDFYNIS-------IVENLPNGFSVLQVMATDKD 334
++ + D NDN P +V + + E++ G +V V D+D
Sbjct: 330 QVTIKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRD 378
Score = 45.2 bits (102), Expect = 0.014
Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDA-EHNLQANTFVLQVQASQLNNPLKTAQ 289
+RY+ I G +F +++ G L + L+ + + Q + F +Q++ + + +A
Sbjct: 53 IRYQ-IQGPADGIFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGV-SAT 110
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DD 347
E+ +LD+ND+ P+F DF + I E+ P A D D G N Y++ +
Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170
Query: 348 PKGAFSI-----DPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
G FS+ P ++ + N LDRE ++ + A
Sbjct: 171 EDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVA 211
Score = 41.9 bits (94), Expect = 0.13
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G+ ++Y LI+GND K F LD G L + + + +++VL ++
Sbjct: 480 IRATDPDSGLNGKIQYSLIAGNDDKTFILDKDRGELVV--------FNYMFQSSYVLTIK 531
Query: 278 ASQLNNPLKTAQARVEIEL 296
AS NP + R+ I +
Sbjct: 532 ASDSGNPPSESLVRIRIRV 550
Score = 40.7 bits (91), Expect = 0.30
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKG 350
+ + D N + P + +I+I++N G V+ + ATD D G NG+ Y L +D K
Sbjct: 446 LHIEDKNRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSLIAGNDDK- 504
Query: 351 AFSIDPRSGWLTVRN 365
F +D G L V N
Sbjct: 505 TFILDKDRGELVVFN 519
>UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to
cadherin-related neuronal receptor 3; n=1; Gallus
gallus|Rep: PREDICTED: similar to cadherin-related
neuronal receptor 3 - Gallus gallus
Length = 695
Score = 93.1 bits (221), Expect = 5e-17
Identities = 117/470 (24%), Positives = 191/470 (40%), Gaps = 57/470 (12%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D L F +VEV + D NDN P F P+ S+ N+ + + A D D+G N +
Sbjct: 109 DRPLRVF-HVEVEVTDINDNAPRF-PNAYKNISVWENSPLNSRFPLEGASDADIGSNAQL 166
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSL 552
Y L + + + V P+ H L + ASD P+
Sbjct: 167 SYSLSPSEHFALDVQRGEENLESLFLVLTKPLDRESLSEHRLVLTASDG-GRPA------ 219
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL 610
T+++ + P F + Y+ + + GT VG++ D E + SY +
Sbjct: 220 LTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQEFSYSI 279
Query: 611 LHGY--EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+ + F+++ R+G I + R + D+E V L E L I
Sbjct: 280 VSSVPASQRDSFSIDPRTGEIRL--------RGLLDYEVVRLCE---LQIEAR------- 321
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
+ G H ++ V + ++ A IG +N Y L D D
Sbjct: 322 ---DNGFPPLSRHCKVVVQVLDGASDADIG----SNAQLSYSLSPSEHFALDVKSPD--D 372
Query: 729 DIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
++ + + PLDRE +R+ + A + G + G Q+ I + D NDN P F
Sbjct: 373 NL---KSLFLVLTHPLDRESLSEHRLVLTAS-DGGRPALTGTVQLVISVLDANDNAPQFN 428
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE----GKEMFDVDENTG 844
+ Y+ + E++ GT + + ATD DEG N F Y++ ++ F +D TG
Sbjct: 429 QSVYKVQLPEDAAEGTLVGR---VAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTG 485
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPE 892
++ G LD E ++L + ARD G LS +I+ + D NDN PE
Sbjct: 486 EIRLTGP-LDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPE 534
Score = 77.8 bits (183), Expect = 2e-12
Identities = 60/176 (34%), Positives = 88/176 (50%), Gaps = 18/176 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNG-----SLFLEKELDLDAEHNLQANTFVL 274
A D D+G A L Y L + + F+LD G SLFL LD E +L + VL
Sbjct: 155 ASDADIGSNAQLSYSL---SPSEHFALDVQRGEENLESLFLVLTKPLDRE-SLSEHRLVL 210
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
AS P T ++ I +LD NDN P+F Y + + E+ G V +V ATD D
Sbjct: 211 T--ASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPD 268
Query: 335 QGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+G N EF+Y + + +FSIDPR+G + +R +LD E +++ A++
Sbjct: 269 EGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLRG--LLDYEVVRLCELQIEARD 322
Score = 75.8 bits (178), Expect = 9e-12
Identities = 62/203 (30%), Positives = 91/203 (44%), Gaps = 13/203 (6%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
A D D G N Q+ Y + + S D +K F++ H + SL SE R
Sbjct: 342 ASDADIGSNAQLSYSLSPSEHFALDVKSPDD-NLKSLFLVLT---HPLDRESL---SEHR 394
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L ++A DGG L + + + V D ND+ P F ++ Y + E ++G+V ATD
Sbjct: 395 LVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDP 454
Query: 1073 DFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
D G N +Y I P+ F I P TG + + G LD E ++ L + ARD G
Sbjct: 455 DEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKG-TP 513
Query: 1130 XXXXXXXXXXXXXDVNDNSPKFY 1152
DVNDN+P+ +
Sbjct: 514 PLSGHCSVILEVLDVNDNAPEVW 536
Score = 72.9 bits (171), Expect = 6e-11
Identities = 73/247 (29%), Positives = 109/247 (44%), Gaps = 18/247 (7%)
Query: 156 NSDVHYSIVSG---NDDGHFALESSHKPVLLLRKVLDYDAGDK-EFQLVIMASG---KRI 208
N + YSIVS + F+++ + L R +LDY+ E Q+ +G
Sbjct: 272 NQEFSYSIVSSVPASQRDSFSIDPRTGEIRL-RGLLDYEVVRLCELQIEARDNGFPPLSR 330
Query: 209 HKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLF--SLDSVNGSLFLEKELDLDAEHN 266
H +++ A D D+G A L Y L L S D SLFL LD E +
Sbjct: 331 HCKVVVQVLDGASDADIGSNAQLSYSLSPSEHFALDVKSPDDNLKSLFLVLTHPLDRE-S 389
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
L + VL AS P T ++ I +LD NDN P+F Y + + E+ G V
Sbjct: 390 LSEHRLVLT--ASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVG 447
Query: 327 QVMATDKDQGENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
+V ATD D+G N F+Y + + +FSIDPR+G + + + L+++
Sbjct: 448 RVAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEDVHQHELQIEA 507
Query: 382 YAKETNP 388
K T P
Sbjct: 508 RDKGTPP 514
Score = 71.7 bits (168), Expect = 1e-10
Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 16/192 (8%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P+ + A D D G N Q+ Y + + AL+V+R N +
Sbjct: 142 ENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHF--------ALDVQRGEE-NLESLFL 192
Query: 1002 IVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
++ + L ES E RL ++A DGG L + + + V D ND+ P F ++ Y + E
Sbjct: 193 VLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPED 252
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFI---QPSDTDLPFEISPLTGVLSVNGELDRETED 1114
++G+V ATD D G N +Y I P+ F I P TG + + G LD E
Sbjct: 253 AAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDYEVVR 312
Query: 1115 KYILTVVARDNG 1126
L + ARDNG
Sbjct: 313 LCELQIEARDNG 324
Score = 69.7 bits (163), Expect = 6e-10
Identities = 60/230 (26%), Positives = 100/230 (43%), Gaps = 12/230 (5%)
Query: 160 HYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPI 218
H +++ +D G AL + V L+ VLD + +F Q V E +
Sbjct: 393 HRLVLTASDGGRPALTGT---VQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRV 449
Query: 219 HAIDQDLGVGATLRYELISG---NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
A D D G+ Y ++S + R FS+D G + L LD + H + LQ
Sbjct: 450 AATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEDVHQHE-----LQ 504
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
++A P + V +E+LD+NDN PE V ++ + E+ G V + +D+D
Sbjct: 505 IEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDS 564
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G NG + P + +G ++ + LDRE S ++V A++
Sbjct: 565 GPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVGAED 614
Score = 67.3 bits (157), Expect = 3e-09
Identities = 57/213 (26%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
+E AG +G++ ++ G L+A + + +++ A G + LDRE+
Sbjct: 35 EEAEAGTVVGRLAQ-DLGLEAGEAEARRLRLVARGRRASVEVSGAS-GALVVSSRLDREE 92
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
+ ++ V + + D NDN P F +A + ENS + + +
Sbjct: 93 LCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPL 152
Query: 809 DNIIKATDADEGTNALFMYTLFGEGKEMFDV---DENT-GVVKFIGDSLDREKKIMYKLS 864
+ A+DAD G+NA Y+L DV +EN + + LDRE ++L
Sbjct: 153 EG---ASDADIGSNAQLSYSLSPSEHFALDVQRGEENLESLFLVLTKPLDRESLSEHRLV 209
Query: 865 LVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
L A D G L+ +L+I + D NDN P+FNQ
Sbjct: 210 LTASDGGRPALTGTVQLVISVLDANDNAPQFNQ 242
Score = 66.9 bits (156), Expect = 4e-09
Identities = 73/290 (25%), Positives = 125/290 (43%), Gaps = 23/290 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V + +++LDANDN P F S +Y+ + +A GT++G+V A DPD G N Y
Sbjct: 407 LTGTVQLVISVLDANDNAPQFNQS-VYKVQLPEDAAEGTLVGRVAATDPDEGINQAFSYS 465
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
+ + + F I+P TG + + E +H L +EA D+ P S+ +
Sbjct: 466 IVSSVPASQRDSFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEV 525
Query: 557 IEVTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
++V N P++ + P V + +GT V + V+D + + +
Sbjct: 526 LDV----NDNAPEVWVTSLSVP----VPEDAALGTVVALLSVSD--RDSGPNGRVRCAVR 575
Query: 616 EGVPFA-VEERSGVITVV--DDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND 671
PF V +G ++V + L R Y+ E A A L V V DVND
Sbjct: 576 PPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVGAEDGGAPPLRASRGLRVPVSDVND 635
Query: 672 ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ ++ + + N+AGA + +++ + G G V + +A
Sbjct: 636 NAPAFAQAVYT--VLARENNAAGAELARLWARDPDEA---GNGRVSYSVA 680
Score = 60.1 bits (139), Expect = 5e-07
Identities = 53/181 (29%), Positives = 86/181 (47%), Gaps = 15/181 (8%)
Query: 223 QDLGVGA----TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
QDLG+ A R L++ R + +G+L + LD + A L+++
Sbjct: 48 QDLGLEAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPC-ALRLEV 106
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
L+ PL+ VE+E+ D+NDN P F + NIS+ EN P A+D D G N
Sbjct: 107 L-LDRPLRVFH--VEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSN 163
Query: 339 GEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE-TNPSVVG 392
+ +Y L P F++D + G + + + LDRE+ S R+ + A + P++ G
Sbjct: 164 AQLSYSL-SPSEHFALDVQRGEENLESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTG 222
Query: 393 T 393
T
Sbjct: 223 T 223
Score = 59.3 bits (137), Expect = 8e-07
Identities = 71/249 (28%), Positives = 102/249 (40%), Gaps = 22/249 (8%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L GT +I V N A +Q +PE+ GT + ++ A D D G+N Y
Sbjct: 407 LTGTVQL-VISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQAFSYS 465
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--L 1025
S V P S+ + F I+ R G + + L E + L I A D G L
Sbjct: 466 IVSSV--PASQRDS--------FSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPL 515
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
+ + SV + V DVND+ P T + V E V+ + +D D G N + ++
Sbjct: 516 SGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVR 575
Query: 1086 PSDTDLPFE-ISPLTGVLS--VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
P PF ++ G S + LDRE +Y + V A D G
Sbjct: 576 PPS---PFGLVATFAGSYSLVLREALDRERVSEYEVEVGAEDGG-APPLRASRGLRVPVS 631
Query: 1143 DVNDNSPKF 1151
DVNDN+P F
Sbjct: 632 DVNDNAPAF 640
Score = 54.8 bits (126), Expect = 2e-05
Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 13/169 (7%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I+EV N A +V +PE+ +GT + L+ D DSG NG++R P
Sbjct: 522 ILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVR-----P 576
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVFV 1035
PS A Y ++ A SE+ + + A DGG L + +RV V
Sbjct: 577 PSPFGLVATFAGSYSLVLRE------ALDRERVSEYEVEVGAEDGGAPPLRASRGLRVPV 630
Query: 1036 KDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
DVND+ P F + Y E L ++ A D D N ++Y +
Sbjct: 631 SDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSV 679
Score = 52.4 bits (120), Expect = 9e-05
Identities = 76/354 (21%), Positives = 135/354 (38%), Gaps = 24/354 (6%)
Query: 484 AVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASD 540
A D D+G N + Y L + + + + V P+ H L + ASD
Sbjct: 342 ASDADIGSNAQLSYSLSPSEHFALDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASD 401
Query: 541 QPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA 600
P+ T+++ + P F + Y+ + + GT VG++ D
Sbjct: 402 G-GRPA------LTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDP 454
Query: 601 FE--QNDVSYDLLHGY--EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN- 655
E SY ++ + F+++ R+G I + L + ++ + A +
Sbjct: 455 DEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPP 514
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN 715
LS + + V+DVND + + S V E++A + + ++S G
Sbjct: 515 LSGHCSVILEVLDVNDNAPEVWVTSLS---VPVPEDAALGTVVALL--SVSDRDSGPNGR 569
Query: 716 VRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
VR + A ++ ++ LDRE+ Y + V AE + G + +
Sbjct: 570 VRCAVRPPSPFGLVATFAGSYSLVLREALDRERVSEYEVEVGAE-DGGAPPLRASRGLRV 628
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+ D NDN P F A Y EN+ G E+ + A D DE N Y++
Sbjct: 629 PVSDVNDNAPAFAQAVYTVLARENNAAGAELAR---LWARDPDEAGNGRVSYSV 679
Score = 49.2 bits (112), Expect = 9e-04
Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Query: 814 ATDADEGTNALFMYTLFGEGKEMFDV---DENT-GVVKFIGDSLDREKKIMYKLSLVARD 869
A+DAD G+NA Y+L DV D+N + + LDRE ++L L A D
Sbjct: 342 ASDADIGSNAQLSYSLSPSEHFALDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASD 401
Query: 870 TG--GLSSEAELIIMIGDENDNKPEFNQ 895
G L+ +L+I + D NDN P+FNQ
Sbjct: 402 GGRPALTGTVQLVISVLDANDNAPQFNQ 429
Score = 43.2 bits (97), Expect = 0.056
Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 6/162 (3%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I PLD E + + + A +KG +G V + + D NDN P +
Sbjct: 485 GEIRLTGPLDFEDVHQHELQIEAR-DKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVP 543
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E++ +GT + + + +D D G N + + ++LDR
Sbjct: 544 VPEDAALGTVVAL---LSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDR 600
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
E+ Y++ + A D G L + L + + D NDN P F Q
Sbjct: 601 ERVSEYEVEVGAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQ 642
Score = 41.9 bits (94), Expect = 0.13
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 9/139 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D+D G +R + + L + + + SL L + LD + + + + ++V A
Sbjct: 561 DRDSGPNGRVRCAVRPPSPFGLVATFAGSYSLVLREALDRE-----RVSEYEVEVGAEDG 615
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
P A + + + D+NDN P F Y + EN G + ++ A D D+ NG
Sbjct: 616 GAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRV 675
Query: 342 TYQLDDPKGAFSIDPRSGW 360
+Y + + GA S SGW
Sbjct: 676 SYSVAE-GGAGS---GSGW 690
Score = 39.9 bits (89), Expect = 0.53
Identities = 61/281 (21%), Positives = 108/281 (38%), Gaps = 17/281 (6%)
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-Y 1152
E+S +G L V+ LDRE R D+NDN+P+F
Sbjct: 74 EVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPN 133
Query: 1153 AFDELLEWKHPEADE---LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN-DTDFIG 1208
A+ + W++ + L + + ++ + V + N ++ F+
Sbjct: 134 AYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVQRGEENLESLFLV 193
Query: 1209 NGNGLILYSLPQRK---NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELE 1265
L SL + + + G P+L+ T L+++V D D P F Y+++
Sbjct: 194 LTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNA-----PQFNQSVYKVQ 248
Query: 1266 IEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDR 1323
+ E+ + + T+ E N + Y I++ R +F IDPR G + L D
Sbjct: 249 LPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDY 308
Query: 1324 EVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
EV E+ + A + H V VL+G + D+
Sbjct: 309 EVVRLCELQIEARDNGFPPLSRHC--KVVVQVLDGASDADI 347
>UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio
"Paraxial protocadherin.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Paraxial protocadherin. -
Takifugu rubripes
Length = 980
Score = 93.1 bits (221), Expect = 5e-17
Identities = 116/482 (24%), Positives = 203/482 (42%), Gaps = 29/482 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + D NDN+PVF N + ++ +A VGTVI + AVD D G NG V+Y + +
Sbjct: 207 ITILVTDFNDNSPVF-DQNSFSVTLPEDAPVGTVILNLNAVDADDGLNGEVVYGFGKQVS 265
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
I F+++ +G +++ E + + L V+A+D ANPS SL + I +T
Sbjct: 266 HEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPSP---SLCKIIIHIT-D 321
Query: 563 TKGNKPDI---PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGV 618
N P+I P ++ + V I D N + L+G++
Sbjct: 322 VNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQVHCSLYGHDHFK 381
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVLL 677
E S +I L R Y+ +A + + + T+ + D ND
Sbjct: 382 LRQAYEDSYMIVTAASLDRERISEYNLTVMAEDFGSPPMRKIIQYTIRLSDENDNAPHFA 441
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL--IANQQDVTDDIAI-AE 734
+G + V+ N GA I + + + + NG R + + V +++ +
Sbjct: 442 RGVTEVSV--VENNPPGAYITTV-EASDADLANNGKITYRLVDSVIMGSPVNTFVSLNSV 498
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP-VFEHATYE 793
G+++ + + E + V A + G + + I D+NDN P + E Y+
Sbjct: 499 SGSLYALRSFNYEVMKQLDVHVQAS-DGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLYK 557
Query: 794 G----FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI 849
G F+ ++S G + IKATDADEG NA Y + G F ++++TG V +
Sbjct: 558 GSAEVFLPKDSPGGYVLTQ---IKATDADEGINAQLSYKIIEGGHLGFSINKDTGKV-HV 613
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEEN-SKVRIHRET 908
L + K+++ D G S + II + P + +N S+V +T
Sbjct: 614 SRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTEGTLPSVPSLAQNDSEVFFEWDT 673
Query: 909 KL 910
+
Sbjct: 674 SI 675
Score = 85.4 bits (202), Expect = 1e-14
Identities = 78/286 (27%), Positives = 137/286 (47%), Gaps = 22/286 (7%)
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV-VDVNDERGVLLKGA 680
V E G +TV + + R + + + + N S +HV V++ D +
Sbjct: 54 VRESDGELTVGERIDRERICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEFP 113
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIANQQDVTDDIAIAEDGTIF 739
+ I + EN AA+G + ++ G+ ++ + I+ T D+ + DG +
Sbjct: 114 NKESIVEISEN---AAVGSRVPLDPAADADVGSNYIQSYQISVNSHFTIDVLLRADGVKY 170
Query: 740 TQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
+ K LDRE + Y + ++A + G +G ++TI + D NDN PVF+ ++
Sbjct: 171 AELVLMKELDRETQSSYTVDLVAT-DGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVT 229
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG-----EGKEMFDVDENTGVVKFIG 850
+ E++ +GT I + A DAD+G N +Y FG E +++F VD +G + +
Sbjct: 230 LPEDAPVGTVILN---LNAVDADDGLNGEVVYG-FGKQVSHEIRQLFQVDHKSGRLT-LR 284
Query: 851 DSLDREKKIMYKLSLVARDTGGLSSEA--ELIIMIGDENDNKPEFN 894
+D E+K Y+L + A D G S + ++II I D NDN PE +
Sbjct: 285 SPVDFEEKTTYELDVQATDLGANPSPSLCKIIIHITDVNDNAPEIS 330
Score = 82.2 bits (194), Expect = 1e-13
Identities = 107/480 (22%), Positives = 194/480 (40%), Gaps = 30/480 (6%)
Query: 429 TENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
T ++ + + ++V V + D NDN+P F P+ + NA VG+ + A D D
Sbjct: 82 TFDVVNFSKDRYKLIHVAVEIRDINDNSPEF-PNKESIVEISENAAVGSRVPLDPAADAD 140
Query: 489 LGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER 548
+G N + Y + S+ TI + + V AE +++ + ++
Sbjct: 141 VGSNYIQSYQISVNSHFTIDVLLRAD----GVKYAELVLMKELDRETQSSYTVDLVATDG 196
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
+ + ++T + P F + + + +GT + + DA + ++
Sbjct: 197 GHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDA--DDGLNG 254
Query: 609 DLLHGYEEGVP------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLS-IVTN 661
++++G+ + V F V+ +SG +T+ + + Y+ + A AN S +
Sbjct: 255 EVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPSPSLCK 314
Query: 662 ATVHVVDVND---ERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+H+ DVND E + + + I ++ E + ++ + T N V
Sbjct: 315 IIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVN--SQVHC 372
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ A + I T LDRE+ Y +TV+AE + G I Q TI +
Sbjct: 373 SLYGHDHFKLRQAYEDSYMIVTAASLDRERISEYNLTVMAE-DFGSPPMRKIIQYTIRLS 431
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-----FGEG 833
DENDN P F E ++EN+ G I ++A+DAD N Y L G
Sbjct: 432 DENDNAPHFARGVTEVSVVENNPPGAYI---TTVEASDADLANNGKITYRLVDSVIMGSP 488
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
F + + S + E + + A D G L + A + + I D+NDN+P
Sbjct: 489 VNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQP 548
Score = 73.3 bits (172), Expect = 5e-11
Identities = 99/445 (22%), Positives = 189/445 (42%), Gaps = 39/445 (8%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+G+ TI+ V N + DQ +PE+ P+GT I+ LNA+D D GLNG++ Y F
Sbjct: 202 SGSTKITIL-VTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDGLNGEVVYGF 260
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-GGNLND 1027
+V + E+++ F ++ + G + + + E + + L++ A D G N +
Sbjct: 261 GKQV----------SHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPSP 310
Query: 1028 NI-SVRVFVKDVNDH------FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
++ + + + DVND+ P+ T + EA ++ + D D G N+ +
Sbjct: 311 SLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQV 370
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
+ D + + ++ LDRE +Y LTV+A D G
Sbjct: 371 HCSLYGHDHFKLRQAYEDSYMIVTAASLDRERISEYNLTVMAEDFG-SPPMRKIIQYTIR 429
Query: 1141 XXDVNDNSPKF---YAFDELLEWKHPEA----DELSNHNFESVMMIPVYKA--TIEENAP 1191
D NDN+P F ++E P A E S+ + + I Y+ ++ +P
Sbjct: 430 LSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKI-TYRLVDSVIMGSP 488
Query: 1192 IGTTVAKVFANDTDF-IGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVE 1250
+ T V+ + + + + + N ++ L + G P L +TA++ + + D D
Sbjct: 489 VNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQP 548
Query: 1251 MSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVI 1308
+ +P E+ + ++ L + T+ E N ++ Y I+ F I
Sbjct: 549 LIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGGHLG----FSI 604
Query: 1309 DPRNGTLYLVRSPDREVKDTYEVIV 1333
+ G +++ R ++ DT +V V
Sbjct: 605 NKDTGKVHVSRQLTYDLSDTVKVTV 629
Score = 67.3 bits (157), Expect = 3e-09
Identities = 77/297 (25%), Positives = 115/297 (38%), Gaps = 20/297 (6%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIG 125
DLV G S +T+ + D NDN P+F + VT+ E P G
Sbjct: 190 DLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDAD 249
Query: 126 PSLTIPLTVPRGLTIFKDIRA-FDRDKPN---TPNSDVHYSIVSGNDDGHFALESSHKPV 181
L + G + +IR F D + T S V + + + A + P
Sbjct: 250 DGLNGEVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPS 309
Query: 182 LLLRKVLDY--DAGDKEFQLVI-----MASGKRIHKEILFPEPIHAI----DQDLGVGAT 230
L K++ + D D ++ I M +G E + + A+ D+D GV +
Sbjct: 310 PSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQ 369
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ L + KL + S + LD E + N L V A +P
Sbjct: 370 VHCSLYGHDHFKL--RQAYEDSYMIVTAASLDRERISEYN---LTVMAEDFGSPPMRKII 424
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+ I L D NDN P F +S+VEN P G + V A+D D NG+ TY+L D
Sbjct: 425 QYTIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVD 481
Score = 66.5 bits (155), Expect = 5e-09
Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 6/175 (3%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G Y++ + + L +G + E L + + Q++ + + + A+
Sbjct: 136 AADADVGSNYIQSYQISVNSHFTIDVLLRADGVKYAELVLMKELDRETQSS-YTVDLVAT 194
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
+P ++ ++ I + D NDN P F+ + +++++ E+ P G +L + A D D G NG
Sbjct: 195 DGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDGLNG 254
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPS 389
E Y + + F +D +SG LT+R+ + + L ++ NPS
Sbjct: 255 EVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPS 309
Score = 62.9 bits (146), Expect = 7e-08
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 16/216 (7%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQKPLDRE 747
+E + G IG + +MS + N R + +Q I + E DG + + +DRE
Sbjct: 15 EEGAPGTVIGTLAK-DMSLSLSSSKTNFRMM---KQFNDSFIRVRESDGELTVGERIDRE 70
Query: 748 KRDVYRMTVIAEFNKGVISGAG--IYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
+ + + F+ S + V + I D NDN P F + I EN+ +G+
Sbjct: 71 RICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEFPNKESIVEISENAAVGSR 130
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGDSLDREKKIMY 861
+ +D A DAD G+N + Y + DV VK+ + LDRE + Y
Sbjct: 131 VPLD---PAADADVGSNYIQSYQISVNSHFTIDVLLRADGVKYAELVLMKELDRETQSSY 187
Query: 862 KLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ LVA D G S ++ I++ D NDN P F+Q
Sbjct: 188 TVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQ 223
Score = 60.1 bits (139), Expect = 5e-07
Identities = 51/187 (27%), Positives = 88/187 (47%), Gaps = 17/187 (9%)
Query: 218 IHAIDQDLGVGATLRYELIS----GNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D DL + Y L+ G+ F SL+SV+GSL+ + + + L +
Sbjct: 462 VEASDADLANNGKITYRLVDSVIMGSPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVH-- 519
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYN----ISIVENLPNGFSVLQ 327
VQAS +P A + +++LD NDN P E Y + + ++ P G+ + Q
Sbjct: 520 ---VQASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQ 576
Query: 328 VMATDKDQGENGEFTYQ-LDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
+ ATD D+G N + +Y+ ++ FSI+ +G + V Q D + + V +
Sbjct: 577 IKATDADEGINAQLSYKIIEGGHLGFSINKDTGKVHVSRQLTYDLSDTVKVTVAV-SDNG 635
Query: 387 NPSVVGT 393
+PS+ T
Sbjct: 636 SPSLTST 642
Score = 58.4 bits (135), Expect = 1e-06
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 18/196 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G I + A D D NG+I Y V + V + +N G
Sbjct: 449 VVENNPPGAYITTVEASDADLANNGKITYRLVDSVIM--------GSPVNTFVSLNSVSG 500
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFP-VFKKTWYNFNV 1054
+ RS E + +++ A DGG+ L +R+ + D ND+ P + + Y +
Sbjct: 501 SLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLYKGSA 560
Query: 1055 E----EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
E + VL ++ ATDAD G NA L+Y I L F I+ TG + V+ +L
Sbjct: 561 EVFLPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGG-HLGFSINKDTGKVHVSRQLTY 619
Query: 1111 ETEDKYILTVVARDNG 1126
+ D +TV DNG
Sbjct: 620 DLSDTVKVTVAVSDNG 635
Score = 49.6 bits (113), Expect = 6e-04
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLY----EFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
QL + + + +LD NDN P+ V LY E + ++ G V+ ++KA D D G N
Sbjct: 529 QLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINA 588
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYS 551
+ Y + +L F IN +TG V V+ L + V SD N S S
Sbjct: 589 QLSYKIIEGGHL----GFSINKDTGKVHVSRQLTYDLSDTVKVTVAVSD---NGSPSLTS 641
Query: 552 LAVVTIEVTRGTKGNKPDI 570
A++ + T GT + P +
Sbjct: 642 TAIIHVSFTEGTLPSVPSL 660
Score = 45.2 bits (102), Expect = 0.014
Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 5/127 (3%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
I V V ++D+ND+ P F + E + A DAD G N +Y I +
Sbjct: 96 IHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQSYQISVNS 155
Query: 1089 TDLPFEISPLTGV----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ GV L + ELDRET+ Y + +VA D G D
Sbjct: 156 HFTIDVLLRADGVKYAELVLMKELDRETQSSYTVDLVATDGG-HPFRSGSTKITILVTDF 214
Query: 1145 NDNSPKF 1151
NDNSP F
Sbjct: 215 NDNSPVF 221
Score = 39.5 bits (88), Expect = 0.69
Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 26/157 (16%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P S + + + V D D + PVF + + + E+ +++LN + +
Sbjct: 197 GHPFRSGSTKITILVTDFND-----NSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDG 251
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP-DREVKDTYEVIVRAERQKYSREL 1344
N ++ Y + +IR+ F +D ++G L L RSP D E K TYE+ V+
Sbjct: 252 LNGEVVYGFGKQVSHEIRQLFQVDHKSGRLTL-RSPVDFEEKTTYELDVQ---------- 300
Query: 1345 PHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
A D+ + K+++ I DVNDN+P+ +
Sbjct: 301 -------ATDLGANPSPSLCKIIIHITDVNDNAPEIS 330
Score = 37.1 bits (82), Expect = 3.7
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V +E+ D+NDN PEF + I EN G V A D D G N +YQ+
Sbjct: 98 VAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQSYQI-SVNSH 156
Query: 352 FSIDP--RSGWLTVRNQTV---LDREAHSSLRMKVYAKE 385
F+ID R+ + + LDRE SS + + A +
Sbjct: 157 FTIDVLLRADGVKYAELVLMKELDRETQSSYTVDLVATD 195
>UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6
SCAF14768, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 697
Score = 93.1 bits (221), Expect = 5e-17
Identities = 72/237 (30%), Positives = 109/237 (45%), Gaps = 8/237 (3%)
Query: 441 SFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ 500
S V V+L D NDN P F ++Y F + NA VGT +G++ A D D+G N + Y L+
Sbjct: 202 SSTTVTVSLTDVNDNGPTF-QHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLE 260
Query: 501 RTSNLTITSPFKINPNT--GTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
+ + T + +P T G V +A+ E + + A P R L
Sbjct: 261 DSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDR 320
Query: 559 VTRGTKGNKPDIPD-FMGAPYEFWVGSNVGIGTSVGQI--RVNDAFEQNDVSYDLLHGYE 615
+T D P F+ YE+ V NV +GT+VG + R DAF+ N V Y + +
Sbjct: 321 MTLKIIVEDVDEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFD-NPVRYSIDRRSD 379
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVND 671
F ++ +G +TVV L R ++F A A + LS + V+D+ND
Sbjct: 380 AISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLFIKVLDIND 436
Score = 90.2 bits (214), Expect = 4e-16
Identities = 114/435 (26%), Positives = 191/435 (43%), Gaps = 41/435 (9%)
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALF 535
VIG++++ D D G++ + Y L S F+I+ +TG + + E + + L
Sbjct: 25 VIGQLRS-DSDRGESS-IRYIL---SGEGAGDLFQIDESTGEIWMLRKLDREEKASYVLQ 79
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
+A ++ ++ E S ++T++ ++P F PYE + +GT+V ++
Sbjct: 80 AQAINRRSSQPEELQSEFIITVQDIND------NVPLFQNEPYESSIPEMCPLGTTVARV 133
Query: 596 RVNDAFEQN-DVSYDLLHGYEEGVP-FAVEERSGVI-TVVDDLSRYNRPMYDFEAVA--- 649
DA + + L++ +G P F+VE ++G+I T ++ R R Y A
Sbjct: 134 TATDADDPMFGNNAKLIYSILQGEPYFSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDM 193
Query: 650 LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSI 708
L + S T TV + DVND H F V EN+A G +G+I + I
Sbjct: 194 LGLSGGHSSSTTVTVSLTDVNDNGPTF---QHHVYAFGVPENAAVGTTVGRIMAED-GDI 249
Query: 709 YGNGTGNVRFLIANQQDVTDDIA---IAEDGTIFTQKPLDRE--KRDVYRMTVIAEFNKG 763
N + + ++ T I + ++G + KPLD E +R V + ++
Sbjct: 250 GINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDT 309
Query: 764 VISGAGIYQ----VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE 819
++ + I +ED D PPVF H YE + EN +GT + + A D D
Sbjct: 310 RFLPLDKFRDRMTLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAV---GSVSARDGDA 365
Query: 820 GTNAL-FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT--GGLSSE 876
N + + + F +D N G V + LDRE + S A++T G LSS
Sbjct: 366 FDNPVRYSIDRRSDAISAFRIDPNNGTVTVV-QPLDRETSAWHNFSAEAKETAQGRLSSS 424
Query: 877 AELIIMIGDENDNKP 891
+L I + D NDN P
Sbjct: 425 VKLFIKVLDINDNVP 439
Score = 81.0 bits (191), Expect = 2e-13
Identities = 62/217 (28%), Positives = 107/217 (49%), Gaps = 18/217 (8%)
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-GTIFTQKP 743
+F +E+ IGQ+ S G ++R++++ + D I E G I+ +
Sbjct: 14 LFVPEEDPTPQVIGQL-----RSDSDRGESSIRYILSGE-GAGDLFQIDESTGEIWMLRK 67
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LDRE++ Y + A + + I ++D NDN P+F++ YE I E +G
Sbjct: 68 LDREEKASYVLQAQAINRRSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLG 127
Query: 804 TEIKMDNIIKATDADE---GTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIM 860
T + + ATDAD+ G NA +Y++ +G+ F V+ TG++ ++DRE +
Sbjct: 128 TTVAR---VTATDADDPMFGNNAKLIYSIL-QGEPYFSVEPKTGIIVTSWPNMDREARDQ 183
Query: 861 YKLSLVARD----TGGLSSEAELIIMIGDENDNKPEF 893
Y + + A+D +GG SS + + + D NDN P F
Sbjct: 184 YLVVVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTF 220
Score = 75.4 bits (177), Expect = 1e-11
Identities = 105/405 (25%), Positives = 168/405 (41%), Gaps = 50/405 (12%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD---LGQNGMVLYDLQRTS 503
+T+ D NDN P+F + YE S+ +GT + +V A D D G N ++Y +
Sbjct: 99 ITVQDINDNVPLF-QNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAKLIYSI---- 153
Query: 504 NLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLAVVTIEV 559
L F + P TG + V P ++ ++ + V+A D S S VT+ +
Sbjct: 154 -LQGEPYFSVEPKTGII-VTSWPNMDREARDQYLVVVQAKDM-LGLSGGHSSSTTVTVSL 210
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA--FEQNDVSYDLLHGYEEG 617
T P F Y F V N +GT+VG+I D +SY L EE
Sbjct: 211 TDVNDNG----PTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSLEES 266
Query: 618 VPFAVE----ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV------TNATVH-V 666
F + + GV+ + L + + A A+ + + + T+ +
Sbjct: 267 GTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRMTLKII 326
Query: 667 VDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQ 724
V+ DE V L H + V EN G A+G + S+ G+ N VR+ I +
Sbjct: 327 VEDVDEPPVFL---HPLYEWKVPENVVVGTAVGSV-----SARDGDAFDNPVRYSIDRRS 378
Query: 725 DVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDEND 782
D I +GT+ +PLDRE + + A E +G +S + ++ I + D ND
Sbjct: 379 DAISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSS--VKLFIKVLDIND 436
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
N P Y+ +I E ++ G ++ +I A D DE Y
Sbjct: 437 NVPRLAR-DYQPYICEGTQPGEPVQ---LISAVDPDEPVEGHHFY 477
Score = 74.5 bits (175), Expect = 2e-11
Identities = 52/168 (30%), Positives = 90/168 (53%), Gaps = 11/168 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA-SQ 280
D D G +++RY L LF +D G +++ ++LD + + ++VLQ QA ++
Sbjct: 32 DSDRGE-SSIRYILSGEGAGDLFQIDESTGEIWMLRKLDRE-----EKASYVLQAQAINR 85
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---GE 337
++ + Q+ I + D+NDN+P F+ + Y SI E P G +V +V ATD D G
Sbjct: 86 RSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGN 145
Query: 338 NGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
N + Y + + FS++P++G + V + +DREA + V AK+
Sbjct: 146 NAKLIYSILQGEPYFSVEPKTG-IIVTSWPNMDREARDQYLVVVQAKD 192
Score = 71.7 bits (168), Expect = 1e-10
Identities = 60/191 (31%), Positives = 86/191 (45%), Gaps = 35/191 (18%)
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDT 1089
+ V+D+ND+ P+F+ Y ++ E + +V ATDAD FG NA L Y I +
Sbjct: 99 ITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAKLIYSILQGEP 158
Query: 1090 DLPFEISPLTGVLSVN-GELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDN 1147
F + P TG++ + +DRE D+Y++ V A+D G DVNDN
Sbjct: 159 --YFSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSSTTVTVSLTDVNDN 216
Query: 1148 SPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI 1207
P F +H VY + ENA +GTTV ++ A D D I
Sbjct: 217 GPTF-----------------QHH---------VYAFGVPENAAVGTTVGRIMAEDGD-I 249
Query: 1208 GNGNGLILYSL 1218
G N + YSL
Sbjct: 250 GI-NAKMSYSL 259
Score = 64.5 bits (150), Expect = 2e-08
Identities = 61/228 (26%), Positives = 96/228 (42%), Gaps = 29/228 (12%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE- 996
F +PEN +GTT+ ++ A D D G+N ++ Y D+LE F+I
Sbjct: 227 FGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLE------------DSLEESGTFIIRTD 274
Query: 997 ---RHGHVIVARSLPPESEFRLNISA-----------LDGGNLNDNISVRVFVKDVNDHF 1042
+ G V++A+ L E++ R ++A L D +++++ V+DV D
Sbjct: 275 PVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRMTLKIIVEDV-DEP 333
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
PVF Y + V E +G V A D D N + SD F I P G +
Sbjct: 334 PVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDNPVRYSIDRRSDAISAFRIDPNNGTV 393
Query: 1103 SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+V LDRET + + A++ D+NDN P+
Sbjct: 394 TVVQPLDRETSAWHNFSAEAKET-AQGRLSSSVKLFIKVLDINDNVPR 440
Score = 62.5 bits (145), Expect = 9e-08
Identities = 53/195 (27%), Positives = 91/195 (46%), Gaps = 24/195 (12%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE P+GTT+ ++ A D D + G +KL L+ + YF + + G
Sbjct: 120 IPEMCPLGTTVARVTATDADDPMFGN------------NAKLIYSILQGEPYFSVEPKTG 167
Query: 1000 HVIVA---RSLPPESEFRLNISALD----GGNLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
++ + ++ + + A D G + + +V V + DVND+ P F+ Y F
Sbjct: 168 IIVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTFQHHVYAF 227
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-DTDLPFEI--SPLT--GVLSVNGE 1107
V E +G++ A D D G NA ++Y ++ S + F I P+T GV+ +
Sbjct: 228 GVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKP 287
Query: 1108 LDRETEDKYILTVVA 1122
LD ET+ +++L A
Sbjct: 288 LDFETKRRFVLAAEA 302
Score = 57.6 bits (133), Expect = 2e-06
Identities = 79/322 (24%), Positives = 124/322 (38%), Gaps = 24/322 (7%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP-----IGPSLTIPLTVPRGLT 139
+ ++D+NDNVP+F + PY ++ E+ P G G + + ++ +G
Sbjct: 99 ITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAKLIYSILQGEP 158
Query: 140 IFKDIRAFDRDKPNTPNSDVH----YSIVSGNDDGHFALESSHKPVLLLRKVL-DYDAGD 194
F + PN D Y +V D L H + L D +
Sbjct: 159 YFSVEPKTGIIVTSWPNMDREARDQYLVVVQAKD-MLGLSGGHSSSTTVTVSLTDVNDNG 217
Query: 195 KEFQLVIMASGKRIHKEI-LFPEPIHAIDQDLGVGATLRYELISGNDRK---LFSLDSVN 250
FQ + A G + + I A D D+G+ A + Y L + + D V
Sbjct: 218 PTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSLEESGTFIIRTDPVT 277
Query: 251 --GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN-DNLPEFE 307
G + L K LD + + + PL + R+ ++++ + D P F
Sbjct: 278 QEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRMTLKIIVEDVDEPPVFL 337
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVR 364
Y + EN+ G +V V A D D +N Y +D D AF IDP +G +TV
Sbjct: 338 HPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRYSIDRRSDAISAFRIDPNNGTVTVV 396
Query: 365 NQTVLDREAHSSLRMKVYAKET 386
LDRE + AKET
Sbjct: 397 QP--LDRETSAWHNFSAEAKET 416
Score = 50.0 bits (114), Expect = 5e-04
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 22/141 (15%)
Query: 1250 EMSDKPVFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFV 1307
++ + PVF+ YE ++ ENV V VS + ++N +RY I + +D F
Sbjct: 329 DVDEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRYSI--DRRSDAISAFR 385
Query: 1308 IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVV 1367
IDP NGT+ +V+ DRE + +S E A++ +G VK+
Sbjct: 386 IDPNNGTVTVVQPLDRETSAWH---------NFSAE--------AKETAQGRLSSSVKLF 428
Query: 1368 VRIKDVNDNSPKFTNGNRPLV 1388
+++ D+NDN P+ +P +
Sbjct: 429 IKVLDINDNVPRLARDYQPYI 449
Score = 47.6 bits (108), Expect = 0.003
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 31/174 (17%)
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
W V E T +V+G++ +D+D G+++ + Y + F+I TG + + +L
Sbjct: 11 WKQLFVPEEDPTPQVIGQL-RSDSDRGESS-IRYILSGEGAGDLFQIDESTGEIWMLRKL 68
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
DRE + Y+L A + D+NDN P F
Sbjct: 69 DREEKASYVLQAQAINRRSSQPEELQSEFIITVQDINDNVPLF----------------- 111
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD--FIGNGNGLILYSLPQ 1220
N +ES +I E P+GTTVA+V A D D GN N ++YS+ Q
Sbjct: 112 QNEPYES---------SIPEMCPLGTTVARVTATDADDPMFGN-NAKLIYSILQ 155
Score = 38.3 bits (85), Expect = 1.6
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 11/116 (9%)
Query: 231 LRYELISGNDR-KLFSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKT 287
+RY + +D F +D NG++ + + LD + A HN A +A + +
Sbjct: 370 VRYSIDRRSDAISAFRIDPNNGTVTVVQPLDRETSAWHNFSA-------EAKETAQGRLS 422
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ ++ I++LD+NDN+P D Y I E G V + A D D+ G Y
Sbjct: 423 SSVKLFIKVLDINDNVPRLARD-YQPYICEGTQPGEPVQLISAVDPDEPVEGHHFY 477
>UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173;
Mammalia|Rep: Protocadherin gamma A3 precursor - Homo
sapiens (Human)
Length = 932
Score = 92.7 bits (220), Expect = 7e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 8/165 (4%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
++ LDREK++++++ ++A + ++ + + + D NDNPP+F Y + EN
Sbjct: 197 ERALDREKKEIHQLVLVASDGGDPVHSGNLH-IQVIVLDANDNPPMFTQPEYRVSVWENV 255
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGVVKFIGDSLDREK 857
+GT + N ATD DEG NA Y L G+ E+F ++ +G V + SLD E
Sbjct: 256 PVGTRLLTVN---ATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSIL-KSLDYED 311
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ Y++ + A+D GL S A++++ + D NDN PE S V
Sbjct: 312 AMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSV 356
Score = 86.6 bits (205), Expect = 5e-15
Identities = 114/478 (23%), Positives = 200/478 (41%), Gaps = 39/478 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
++++V +LDANDN P+F Y S+ N VGT + V A DPD G N V Y L +
Sbjct: 226 LHIQVIVLDANDNPPMFTQPE-YRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKM 284
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALF----VEASDQPANPSERRYSLAVVTIE 558
I F +N +G VS+ +S L+ A+F +EA D P S R + V ++
Sbjct: 285 PG-KIAEIFHLNSVSGEVSILKS--LDYEDAMFYEIKIEAQDGPGLLS--RAKILVTVLD 339
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V N P+I VG ++ + D+ + V +L +
Sbjct: 340 V----NDNAPEI-TITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKL 394
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLL 677
++++ ++T L R Y+ A + LS T+ T+HV+D+ND
Sbjct: 395 EKSIDQYYRLVTAT-SLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTF- 452
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ----QDVTDDIAI- 732
H ++ EN+ A IF N + + + ++ ++I
Sbjct: 453 --PHLSYSAYIPENNPRGA--SIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSIN 508
Query: 733 AEDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP--VFEH 789
+ G ++ + D E+ RD+ + ++ +S + +++ D+NDN P ++
Sbjct: 509 SNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSN--VSLNLFVLDQNDNAPEILYPA 566
Query: 790 ATYEGFI-MENSKIGTEI-KMDNIIKATDADEGTNALFMYTLFGEGKE-MFDVDENTGVV 846
+G +E + E + + A D D G NA Y L + +F V +TG V
Sbjct: 567 LPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEV 626
Query: 847 KFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDE-NDNKPEFNQIEENSK 901
+ LDR+ + L + +D G LS+ LI+ + D D + +E ++K
Sbjct: 627 RTARALLDRD-ALKQSLVVAIQDHGQPPLSATVTLIVAVADRIPDILADLGSLEPSAK 683
Score = 80.6 bits (190), Expect = 3e-13
Identities = 68/235 (28%), Positives = 99/235 (42%), Gaps = 27/235 (11%)
Query: 929 LDVDQLGPLFLIPE-------NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LD + P+F PE N+P+GT ++ +NA D D G N Q+ Y + P K+
Sbjct: 233 LDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKM----PGKI 288
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVN 1039
+ F +N G V + +SL E + + I A DG L + V V DVN
Sbjct: 289 A-------EIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVN 341
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLT 1099
D+ P T +V E R + +D D D GQN + F+ +LPF++
Sbjct: 342 DNAPEITITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVEVFVL---GNLPFKLEKSI 398
Query: 1100 GV---LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L LDRE +Y +++ A D G D+NDN P F
Sbjct: 399 DQYYRLVTATSLDREQISEYNISLRASDGG-SPPLSTETHITLHVIDINDNPPTF 452
Score = 69.7 bits (163), Expect = 6e-10
Identities = 51/171 (29%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVN-GSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D+G+ + Y+L S ND +++SV+ G+ + E L+ + + L + A
Sbjct: 157 AFDPDVGINSLQNYKL-SPNDYFSLAVNSVSEGAKYPELVLERALDRE-KKEIHQLVLVA 214
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
S +P+ + +++ +LD NDN P F Y +S+ EN+P G +L V ATD D+G N
Sbjct: 215 SDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFN 274
Query: 339 GEFTYQLDDPKG----AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ +Y LD G F ++ SG +++ LD E +K+ A++
Sbjct: 275 AQVSYILDKMPGKIAEIFHLNSVSGEVSILKS--LDYEDAMFYEIKIEAQD 323
Score = 65.3 bits (152), Expect = 1e-08
Identities = 78/301 (25%), Positives = 124/301 (41%), Gaps = 23/301 (7%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG 137
S L + V + D NDN P+F Y V+V E P G + ++
Sbjct: 223 SGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILD 282
Query: 138 LTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHF---ALESSHKPVLLLR-KVLD--YD 191
K F N+ + +V +D F +E+ P LL R K+L D
Sbjct: 283 KMPGKIAEIFHL---NSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLD 339
Query: 192 AGDKEFQLVIMASGKRIHKEILFPEPIHAID-QDLGVGATLRYEL-ISGNDRKLFSLD-S 248
D ++ I + + +E I ID D G + E+ + GN F L+ S
Sbjct: 340 VNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVEVFVLGN--LPFKLEKS 397
Query: 249 VNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV 308
++ L LD E Q + + + ++AS +P + + + + ++D+NDN P F
Sbjct: 398 IDQYYRLVTATSLDRE---QISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPH 454
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQ 366
Y+ I EN P G S+ V A D D N TY L D +GA P S ++++ +
Sbjct: 455 LSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGA----PLSSFVSINSN 510
Query: 367 T 367
T
Sbjct: 511 T 511
Score = 62.1 bits (144), Expect = 1e-07
Identities = 63/199 (31%), Positives = 93/199 (46%), Gaps = 21/199 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN P G +I + A D DS N +I Y + + + LS+ + IN G
Sbjct: 461 IPENNPRGASIFSVTAQDPDSNNNARITYALTEDT-LQGAPLSS-------FVSINSNTG 512
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFK----KTWYN 1051
+ RS E + +L ++A D GN L+ N+S+ +FV D ND+ P T +
Sbjct: 513 VLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGS 572
Query: 1052 FNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG-VLSVNGE 1107
VE A + ++ KV A D D GQNA L+Y + + F + TG V +
Sbjct: 573 TGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL 632
Query: 1108 LDRETEDKYILTVVARDNG 1126
LDR+ K L V +D+G
Sbjct: 633 LDRDAL-KQSLVVAIQDHG 650
Score = 61.3 bits (142), Expect = 2e-07
Identities = 61/207 (29%), Positives = 91/207 (43%), Gaps = 12/207 (5%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G++ T + +DRE+ + + N V I++V I I+D NDN P F E
Sbjct: 80 QSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELE 139
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----I 849
I E + GT I A D D G N+L Y L V+ + K+ +
Sbjct: 140 IKIGELTVPGTRFP---IKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVL 196
Query: 850 GDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+LDREKK +++L LVA D G S + +++ D NDN P F Q E +V +
Sbjct: 197 ERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPE--YRVSVWEN 254
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQL 934
+ GT T+ P F V +
Sbjct: 255 VPV-GTRLLTVNATDPDEGFNAQVSYI 280
Score = 58.4 bits (135), Expect = 1e-06
Identities = 55/210 (26%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
GT A D D G+N Y+ + Y L+ +++ ++ +++ R+
Sbjct: 149 GTRFPIKTAFDPDVGINSLQNYKLSPNDYF---SLAVNSVSE------GAKYPELVLERA 199
Query: 1007 LPPESE--FRLNISALDGGNL--NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
L E + +L + A DGG+ + N+ ++V V D ND+ P+F + Y +V E
Sbjct: 200 LDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGT 259
Query: 1063 VLGKVDATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTV 1120
L V+ATD D G NA ++Y + P F ++ ++G +S+ LD E Y + +
Sbjct: 260 RLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKI 319
Query: 1121 VARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
A+D DVNDN+P+
Sbjct: 320 EAQDG---PGLLSRAKILVTVLDVNDNAPE 346
Score = 58.0 bits (134), Expect = 2e-06
Identities = 60/220 (27%), Positives = 91/220 (41%), Gaps = 23/220 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE +G I ++ D DSG NGQ+ + P KL + +Y+
Sbjct: 356 VPEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNL---PFKLEKS---IDQYY------- 402
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
++ A SL E SE+ +++ A DGG+ L+ + + V D+ND+ P F Y+ +
Sbjct: 403 RLVTATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIP 462
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-----FIQPSDTDLPFEISPLTGVLSVNGELDR 1110
E + V A D D NA +TY +Q + I+ TGVL D
Sbjct: 463 ENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDY 522
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
E L V A D+G D NDN+P+
Sbjct: 523 EQFRDLKLLVTASDSG-NPPLSSNVSLNLFVLDQNDNAPE 561
Score = 56.8 bits (131), Expect = 4e-06
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 8/169 (4%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + K LD E Y + + A+ G++S A ++ + + D NDN P +
Sbjct: 299 GEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRA---KILVTVLDVNDNAPEITITSLTSS 355
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E +G EI + I D D G N + G + + SLDR
Sbjct: 356 VPEEGTVGREIAL---IDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDR 412
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
E+ Y +SL A D G LS+E + + + D NDN P F + ++ +
Sbjct: 413 EQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYI 461
Score = 46.4 bits (105), Expect = 0.006
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 20/170 (11%)
Query: 218 IHAIDQDLGVGATLRYEL----ISGNDRKLF-SLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D D A + Y L + G F S++S G L+ + D + +L+
Sbjct: 474 VTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLK---- 529
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENLPN----GFSV 325
L V AS NP ++ + + +LD NDN PE + + VE P G+ V
Sbjct: 530 -LLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 326 LQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREA 373
+V+A D+D G+N +Y+L G FS+ +G + + +LDR+A
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTA-RALLDRDA 637
Score = 43.2 bits (97), Expect = 0.056
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 27/175 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYEN 1287
G P S + V V D D + P+F Y + + ENV L+++N T+ E
Sbjct: 218 GDPVHSGNLHIQVIVLDAND-----NPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEG 272
Query: 1288 FKMRY-YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
F + YIL++ I F ++ +G + +++S D E YE+ + A+ + P
Sbjct: 273 FNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQ------DGPG 326
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQV 1401
++ K++V + DVNDN+P+ T + L +++P G ++
Sbjct: 327 LL-------------SRAKILVTVLDVNDNAPEITITS--LTSSVPEEGTVGREI 366
Score = 42.3 bits (95), Expect = 0.099
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 5/120 (4%)
Query: 235 LISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
++S +LFSL+ +GSL + +D + E Q ++++ + + LK + VEI
Sbjct: 66 IVSRGRTQLFSLNPQSGSLVTAERIDRE-ELCAQIPLCLVKINIL-VEDKLKIFE--VEI 121
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
E+ D+NDN P F + I I E G A D D G N Y+L P FS+
Sbjct: 122 EIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKL-SPNDYFSL 180
Score = 41.9 bits (94), Expect = 0.13
Identities = 59/250 (23%), Positives = 95/250 (38%), Gaps = 24/250 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG----M 494
L+S + VT+LD NDN P ++L S+ VG I + D D GQNG
Sbjct: 327 LLSRAKILVTVLDVNDNAPEITITSLTS-SVPEEGTVGREIALIDVHDRDSGQNGQVEVF 385
Query: 495 VLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAV 554
VL +L +I +++ T S+ I E +L P +E +L V
Sbjct: 386 VLGNLPFKLEKSIDQYYRLVTAT---SLDREQISEYNISLRASDGGSPPLSTETHITLHV 442
Query: 555 VTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLH 612
+ I N P P Y ++ N G S+ + D N+ ++Y L
Sbjct: 443 IDI------NDNPPTFPHL---SYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 493
Query: 613 GYEEGVPF----AVEERSGVITVVDDLS-RYNRPMYDFEAVALQENANLSIVTNATVHVV 667
+G P ++ +GV+ + R + + N LS + + V+
Sbjct: 494 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVL 553
Query: 668 DVNDERGVLL 677
D ND +L
Sbjct: 554 DQNDNAPEIL 563
Score = 40.7 bits (91), Expect = 0.30
Identities = 88/367 (23%), Positives = 137/367 (37%), Gaps = 50/367 (13%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V + +KD+ND+ P F + E A D D G N+ Y + P+D
Sbjct: 119 VEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYF 178
Query: 1091 LPFEISPLTGV----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
S G L + LDRE ++ + L +VA D G D ND
Sbjct: 179 SLAVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGG-DPVHSGNLHIQVIVLDAND 237
Query: 1147 NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF 1206
N P F PE Y+ ++ EN P+GT + V A D D
Sbjct: 238 NPPMF---------TQPE-----------------YRVSVWENVPVGTRLLTVNATDPDE 271
Query: 1207 IGNGN-GLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPD------EVEMSDKPVFIS 1259
N IL +P K + L S+S ++ ++ D D ++E D P +S
Sbjct: 272 GFNAQVSYILDKMP-GKIAEIFHLNSVSGEVSILKSL-DYEDAMFYEIKIEAQDGPGLLS 329
Query: 1260 RYYEL--EIEENVNAP-VELVSLNLTEHYENFKMR-YYILNENDTDIRRTFVIDPRNGTL 1315
R L ++ N NAP + + SL + E R +++ +D D + ++
Sbjct: 330 RAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVE----VF 385
Query: 1316 YLVRSPDREVK--DTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDV 1373
L P + K D Y +V A + + I A D + + + + D+
Sbjct: 386 VLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDI 445
Query: 1374 NDNSPKF 1380
NDN P F
Sbjct: 446 NDNPPTF 452
>UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 1259
Score = 92.3 bits (219), Expect = 9e-17
Identities = 117/482 (24%), Positives = 191/482 (39%), Gaps = 34/482 (7%)
Query: 426 GTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV 485
GT +++ E + VEV +LD ND+ P F P Y + +A +G A
Sbjct: 401 GTCLLHLQLLVESPLELYRVEVEVLDINDHAPTF-PWQEYVLEVAESAVLGARFPLESAQ 459
Query: 486 DPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQP 542
DPD+G N + Y L S ++ + + + V E + + H L + A D
Sbjct: 460 DPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALD-- 517
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE 602
RR A V + V +IP F Y + + GT V Q+ D E
Sbjct: 518 -GGIPRRSGTAHVLVTVLDA----NDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDE 572
Query: 603 --QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LS 657
++ Y V F VE RSG + + L +++ A + ++
Sbjct: 573 GPNGEIEYSFSGHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVA 632
Query: 658 IVTNATVHVVDVNDER-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNV 716
+ VH++DVND V L +P+ ++ G I I + S G V
Sbjct: 633 VHCRVLVHLLDVNDNAPEVTLTSVSTPV---QEDAPPGTVIAVISVLDRDS---GDNGRV 686
Query: 717 RFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
++ + + T+ T +PLDRE Y +++ A + G + +T+
Sbjct: 687 SCELSPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITAR-DMGSPALLTRSTLTVP 745
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D NDN P F +Y ++MEN+ G I + A D D NA Y++
Sbjct: 746 VSDVNDNAPHFLQPSYSVYVMENNAPGASICS---VSALDPDCQQNAYLSYSITDGHIHG 802
Query: 837 FDVDENTGVVKFIGD-----SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
V + G SLD E+ +++ + A+D G LS+ + I + D+NDN
Sbjct: 803 MPVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDN 862
Query: 890 KP 891
P
Sbjct: 863 AP 864
Score = 89.8 bits (213), Expect = 5e-16
Identities = 78/248 (31%), Positives = 109/248 (43%), Gaps = 22/248 (8%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+GTA ++ V N DQ +PE+ P GT +I+LNA DLD G NG+I Y F
Sbjct: 524 SGTA-HVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSF 582
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDN 1028
+ + PPS V+ F + R G V++ L E S L + A D G
Sbjct: 583 SG--HAPPS--------VRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVA 632
Query: 1029 ISVRVFVK--DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+ RV V DVND+ P T + V+E V+ + D D G N ++ + P
Sbjct: 633 VHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELSP 692
Query: 1087 SDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
S +PFE+ L LDRE +Y +++ ARD G D
Sbjct: 693 S---VPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMG-SPALLTRSTLTVPVSD 748
Query: 1144 VNDNSPKF 1151
VNDN+P F
Sbjct: 749 VNDNAPHF 756
Score = 79.8 bits (188), Expect = 5e-13
Identities = 56/177 (31%), Positives = 84/177 (47%), Gaps = 8/177 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + Y+L + L + S F E L+ + Q T L + A
Sbjct: 458 AQDPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVLERALDRE-QQRTHRLLLTAL 516
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ A V + +LD NDN+P F+ Y +S+ E+ P G V+Q+ ATD D+G NG
Sbjct: 517 DGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNG 576
Query: 340 EFTYQLD-----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
E Y + F ++PRSG + ++ LD E S + V AK+ PS V
Sbjct: 577 EIEYSFSGHAPPSVRELFRVEPRSGQVLLKGP--LDYERASLHELYVQAKDRGPSAV 631
Score = 77.8 bits (183), Expect = 2e-12
Identities = 109/469 (23%), Positives = 205/469 (43%), Gaps = 58/469 (12%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V VT+LDANDN P F + Y S+ +A GT++ ++ A D D G NG + Y +
Sbjct: 528 HVLVTVLDANDNIPAFDQPS-YGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHA 586
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR---HALFVEASDQPANPSERRYSLAVVTIEVT 560
++ F++ P +G V + + P+ R H L+V+A D+ + + V ++V
Sbjct: 587 PPSVRELFRVEPRSGQV-LLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDV- 644
Query: 561 RGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
N P++ + P V + GT + I V D+ + VS +L
Sbjct: 645 ---NDNAPEVTLTSVSTP----VQEDAPPGTVIAVISVLDRDSGDNGRVSCEL----SPS 693
Query: 618 VPFAVEERSG---VITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVDVNDE 672
VPF + + + L R Y+ ++ ++ + +++T + TV V DVND
Sbjct: 694 VPFELRSSFRDYYTLVTTEPLDREAVSEYNI-SITARDMGSPALLTRSTLTVPVSDVNDN 752
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQI------FHTNMSSIYGNGTGNVRFL-IANQQD 725
L+ ++S ++ ++ N+ GA+I + N Y G++ + +
Sbjct: 753 APHFLQPSYS--VYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTYVS 810
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ D G ++ + LD E+ +++ V A+ + G + V I++ D+NDN P
Sbjct: 811 INSD-----SGHMYALRSLDYEQIRSFQIQVQAQ-DAGFPPLSANVTVHIFVLDQNDNAP 864
Query: 786 VFEHATYEGFIMENSKIGTEI--------KMDNIIKATDADEGTNALFMYTLF-GEGKEM 836
V + N + TE+ + + A DAD G N+ Y L +
Sbjct: 865 VIVSP-----MPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTL 919
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
F + +TG ++ + L+++ +L + RD G LS+ L++ +
Sbjct: 920 FSLAPDTGELRTLRSFLEQD-AARQRLVVQVRDGGQPALSATVSLLLSV 967
Score = 73.7 bits (173), Expect = 3e-11
Identities = 63/240 (26%), Positives = 113/240 (47%), Gaps = 22/240 (9%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVR-FLIAN 722
V V+D+ND P +V E + A +G F + GT +V + ++
Sbjct: 422 VEVLDINDHAPTF------PWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSP 475
Query: 723 QQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ ++ D + F + + LDRE++ +R+ + A + G+ +G V + +
Sbjct: 476 NSFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTA-LDGGIPRRSGTAHVLVTVL 534
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG----K 834
D NDN P F+ +Y + E++ GT + + ATD DEG N Y+ G +
Sbjct: 535 DANDNIPAFDQPSYGVSLPEDAPAGTLVIQ---LNATDLDEGPNGEIEYSFSGHAPPSVR 591
Query: 835 EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPE 892
E+F V+ +G V G LD E+ +++L + A+D G ++ +++ + D NDN PE
Sbjct: 592 ELFRVEPRSGQVLLKG-PLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPE 650
Score = 68.1 bits (159), Expect = 2e-09
Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 12/187 (6%)
Query: 717 RFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
RF I V + + E+G +F + +DRE+ T + V S +Y+V +
Sbjct: 363 RFRIVTGAGVRQHLEVNLENGILFVNERIDREEVCETGGTCLLHLQLLVESPLELYRVEV 422
Query: 776 YIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE 835
+ D ND+ P F Y + E++ +G +++ A D D GTN++ Y L
Sbjct: 423 EVLDINDHAPTFPWQEYVLEVAESAVLGARFPLES---AQDPDVGTNSVHTYQLSPNSFF 479
Query: 836 MFDVDENTGVVKF----IGDSLDREKKIMYKLSLVARDTGGL---SSEAELIIMIGDEND 888
+V + KF + +LDRE++ ++L L A D GG+ S A +++ + D ND
Sbjct: 480 SLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALD-GGIPRRSGTAHVLVTVLDAND 538
Query: 889 NKPEFNQ 895
N P F+Q
Sbjct: 539 NIPAFDQ 545
Score = 66.1 bits (154), Expect = 7e-09
Identities = 67/215 (31%), Positives = 96/215 (44%), Gaps = 27/215 (12%)
Query: 930 DVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLS 982
DV+ P FL P EN G +I ++ALD D N + Y ++ +I
Sbjct: 748 DVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSI-TDGHI------ 800
Query: 983 ADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDV 1038
+ V Y IN GH+ RSL E F++ + A D G L+ N++V +FV D
Sbjct: 801 -HGMPVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQ 859
Query: 1039 NDHFPVFKKTW-YNFNVEEAQYTRR-----VLGKVDATDADFGQNANLTY-FIQPSDTDL 1091
ND+ PV N +V R ++G V A DAD G N+ L+Y +Q +D L
Sbjct: 860 NDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTL 919
Query: 1092 PFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
F ++P TG L + + L V RD G
Sbjct: 920 -FSLAPDTGELRTLRSFLEQDAARQRLVVQVRDGG 953
Score = 63.7 bits (148), Expect = 4e-08
Identities = 48/173 (27%), Positives = 80/173 (46%), Gaps = 12/173 (6%)
Query: 218 IHAIDQDLGVGATLRYELISGND----RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV 273
++A D D G + Y SG+ R+LF ++ +G + L+ LD + +A+
Sbjct: 565 LNATDLDEGPNGEIEYSF-SGHAPPSVRELFRVEPRSGQVLLKGPLDYE-----RASLHE 618
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L VQA RV + LLD+NDN PE + + + E+ P G + + D+
Sbjct: 619 LYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDR 678
Query: 334 DQGENGEFTYQLDDPKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G+NG + +L P F + + T+ LDREA S + + A++
Sbjct: 679 DSGDNGRVSCEL-SPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARD 730
Score = 54.8 bits (126), Expect = 2e-05
Identities = 44/140 (31%), Positives = 73/140 (52%), Gaps = 10/140 (7%)
Query: 221 IDQDLGVG-ATL---RYELISGND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ +DLG+ +TL R+ +++G R+ ++ NG LF+ + +D + E T +L
Sbjct: 348 LGEDLGLDVSTLSARRFRIVTGAGVRQHLEVNLENGILFVNERIDRE-EVCETGGTCLLH 406
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+Q + +PL+ RVE+E+LD+ND+ P F Y + + E+ G A D D
Sbjct: 407 LQLL-VESPLELY--RVEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDV 463
Query: 336 GENGEFTYQLDDPKGAFSID 355
G N TYQL P FS++
Sbjct: 464 GTNSVHTYQL-SPNSFFSLE 482
Score = 54.8 bits (126), Expect = 2e-05
Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 6/162 (3%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + PLD E+ ++ + V A+ ++G + A +V +++ D NDN P +
Sbjct: 601 GQVLLKGPLDYERASLHELYVQAK-DRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTP 659
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E++ GT I +I D D G N L + LDR
Sbjct: 660 VQEDAPPGTVIA---VISVLDRDSGDNGRVSCELSPSVPFELRSSFRDYYTLVTTEPLDR 716
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
E Y +S+ ARD G L + + L + + D NDN P F Q
Sbjct: 717 EAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQ 758
Score = 54.8 bits (126), Expect = 2e-05
Identities = 64/223 (28%), Positives = 97/223 (43%), Gaps = 31/223 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ E+ P GT I ++ LD DSG NG++ E + V P +L + + Y+ +
Sbjct: 660 VQEDAPPGTVIAVISVLDRDSGDNGRVSCELSPSV---PFELRSS---FRDYYTL----- 708
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ L E SE+ ++I+A D G+ L ++ V V DVND+ P F + Y+ V
Sbjct: 709 --VTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQPSYSVYVM 766
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE-------- 1107
E + V A D D QNA L+Y I TD P+ +S+N +
Sbjct: 767 ENNAPGASICSVSALDPDCQQNAYLSYSI----TDGHIHGMPVGTYVSINSDSGHMYALR 822
Query: 1108 -LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
LD E + + V A+D G D NDN+P
Sbjct: 823 SLDYEQIRSFQIQVQAQDAG-FPPLSANVTVHIFVLDQNDNAP 864
Score = 54.4 bits (125), Expect = 2e-05
Identities = 74/337 (21%), Positives = 136/337 (40%), Gaps = 27/337 (8%)
Query: 67 LVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI-- 124
L + G+ + S V V + D NDN+P F Y V++ E P G +
Sbjct: 513 LTALDGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDE 572
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPN----SDVHYSIVSGNDDGHFALESSHKP 180
GP+ I + +R R +P + + Y S ++ A +
Sbjct: 573 GPNGEIEYSFSGHAP--PSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSA 630
Query: 181 VLLLRKVLDY--DAGDKEFQLVIMASGKRIHKEI---LFPEPIHAIDQDLGVGATLRYEL 235
V + +VL + D D ++ + + + ++ I +D+D G + EL
Sbjct: 631 VAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCEL 690
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
+L S +L + LD +A + + + + A + +P ++ + +
Sbjct: 691 SPSVPFELRSSFRDYYTLVTTEPLDREA-----VSEYNISITARDMGSPALLTRSTLTVP 745
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD------PK 349
+ D+NDN P F Y++ ++EN G S+ V A D D +N +Y + D P
Sbjct: 746 VSDVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPV 805
Query: 350 GAF-SIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G + SI+ SG + LD E S +++V A++
Sbjct: 806 GTYVSINSDSGHMYALRS--LDYEQIRSFQIQVQAQD 840
Score = 52.0 bits (119), Expect = 1e-04
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 24/156 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G+P S TA ++VTV D D + D+P Y + + E+ A ++ LN T+ E
Sbjct: 519 GIPRRSGTAHVLVTVLDANDNIPAFDQP-----SYGVSLPEDAPAGTLVIQLNATDLDEG 573
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y +R F ++PR+G + L++ P Y R
Sbjct: 574 PNGEIEYSFSGHAPPSVRELFRVEPRSGQV-LLKGP----------------LDYERASL 616
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFT 1381
H +Y A+D +V+V + DVNDN+P+ T
Sbjct: 617 HELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVT 652
Score = 51.2 bits (117), Expect = 2e-04
Identities = 79/315 (25%), Positives = 126/315 (40%), Gaps = 29/315 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGP------ 126
G + ++ + V V++ DVNDN P T V E P G + +
Sbjct: 627 GPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRV 686
Query: 127 SLTIPLTVPRGL-TIFKDIRAFDRDKPNTPNSDVHYSI-VSGNDDGHFALESSHKPVLLL 184
S + +VP L + F+D +P + Y+I ++ D G AL + + +
Sbjct: 687 SCELSPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPV 746
Query: 185 RKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKL- 243
V D + + + + A+D D A L Y + G+ +
Sbjct: 747 SDVNDNAPHFLQPSYSVYVMENNAPGASICS--VSALDPDCQQNAYLSYSITDGHIHGMP 804
Query: 244 ----FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
S++S +G ++ + LD + Q +F +QVQA P +A V I +LD
Sbjct: 805 VGTYVSINSDSGHMYALRSLDYE-----QIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQ 859
Query: 300 NDNLPEFEVDF-YNISI-VENLPN----GFSVLQVMATDKDQGENGEFTYQLDDPKG--A 351
NDN P N S+ E +P G+ V V A D D G N +YQL
Sbjct: 860 NDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTL 919
Query: 352 FSIDPRSGWL-TVRN 365
FS+ P +G L T+R+
Sbjct: 920 FSLAPDTGELRTLRS 934
Score = 48.0 bits (109), Expect = 0.002
Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 12/126 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFV---PSN--LYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L + V V + +LD NDN PV V P N + + +A G ++G V AVD D G N
Sbjct: 846 LSANVTVHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNS 905
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASD--QPANPSERR 549
+ Y L + ++ T+ F + P+TG + S + + R L V+ D QPA +
Sbjct: 906 RLSYQLLQATDFTL---FSLAPDTGELRTLRSFLEQDAARQRLVVQVRDGGQPALSATVS 962
Query: 550 YSLAVV 555
L+VV
Sbjct: 963 LLLSVV 968
Score = 41.9 bits (94), Expect = 0.13
Identities = 54/192 (28%), Positives = 72/192 (37%), Gaps = 35/192 (18%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V V D+NDH P F Y V E+ A D D G N+ TY + P ++
Sbjct: 420 VEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSP-NSF 478
Query: 1091 LPFEISPLTGV-----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
E+ + L + LDRE + + L + A D G D N
Sbjct: 479 FSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALDGG-IPRRSGTAHVLVTVLDAN 537
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DN P AFD+ P Y ++ E+AP GT V ++ N TD
Sbjct: 538 DNIP---AFDQ-----------------------PSYGVSLPEDAPAGTLVIQL--NATD 569
Query: 1206 FIGNGNGLILYS 1217
NG I YS
Sbjct: 570 LDEGPNGEIEYS 581
>UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia
psychrerythraea 34H|Rep: Cadherin domain protein -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 2193
Score = 92.3 bits (219), Expect = 9e-17
Identities = 113/459 (24%), Positives = 192/459 (41%), Gaps = 36/459 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + + D ++ P+ + S ++ N+ G V+ V + D G Y L+ +
Sbjct: 1502 ITLDITDLDEVGPI-ITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTYSLKSGDD 1560
Query: 505 LTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ + F IN +TG V++ P E + + V ASD N SE+ +L ++ ++
Sbjct: 1561 VAL---FTINSSTGAVTLTADPDDESKADYNFTVVASDGAGNSSEKAITLDIIDLDEVA- 1616
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPF 620
P A + N G G V + D + + +Y L G ++ F
Sbjct: 1617 --------PTITSAAIAAAIDENSGAGQVVYTVMSTDNGDIATDATTYSLKSG-DDAALF 1667
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
+ +G +T+ + + Y+F VA + A S T+ + D+ DE + A
Sbjct: 1668 TINSSTGAVTLTANPDDEGKANYNFTVVA-SDGAGNSSEKAITLDITDL-DEVAPTITSA 1725
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGN-GTGNVRFLIANQQDVTDDIAIAEDGTI- 738
S + ENS GA GQ+ +T S+ G+ TG + + D + G +
Sbjct: 1726 SSATA--IDENS-GA--GQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTINSTSGAVT 1780
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
T P D K D Y TV+A + G S VT+ I D ++ P A I E
Sbjct: 1781 LTANPNDETKAD-YNFTVVATDSPGNNSEKA---VTLDITDLDEIAPTITSAATATAIDE 1836
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREK 857
NS G + + +TD+ + +Y+L G+ +F ++ +TG V + D E
Sbjct: 1837 NSGAGQVVYT---VTSTDSGDVAIGATVYSLKTGDDAALFTINSSTGAVTLTANP-DDET 1892
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
K Y +VA DTG SSE + + I D ++ P N +
Sbjct: 1893 KADYSFIVVATDTGNNSSEQVVTLDINDLDEVAPIINSV 1931
Score = 84.6 bits (200), Expect = 2e-14
Identities = 105/430 (24%), Positives = 181/430 (42%), Gaps = 33/430 (7%)
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
++ N+ G V+ V + D G Y L+ + + F IN +TG V++ P
Sbjct: 597 TIDENSGSGQVVYTVTSTDSSDITTGATSYSLKAGDDAAL---FNINSSTGAVTLTADPD 653
Query: 528 LEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSN 585
E + + V ASD N E+ +L ++ ++ P A + N
Sbjct: 654 DETKADYNFTVLASDAAGNSREQAITLDIIDLDDVA---------PTITSASSATALDEN 704
Query: 586 VGIGTSVGQIRVNDAFEQNDVSYDL-LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
G G V + D+ + + S D L ++ F + +G +T+ D + Y+
Sbjct: 705 SGAGQVVYTVTSTDSDDVSSGSTDYSLKTGDDAALFTINSSTGAVTLSADPDDETKADYN 764
Query: 645 FEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTN 704
F VA ++A S T+ ++D+++ + A I + ENS GA GQ+ +T
Sbjct: 765 FTVVA-SDSAGNSTEQAITLDIIDLDEVAPTITSTA---IAAALDENS-GA--GQVVYTV 817
Query: 705 MSSIYGN-GTGNVRFLIANQQDVTDDIAIAEDGTI-FTQKPLDREKRDVYRMTVIAEFNK 762
S+ G+ TG + + D + G + P D K D Y TV+A +
Sbjct: 818 TSTDSGDIATGATAYSLKIGDDAALFTINSGTGEVTLIANPDDETKAD-YNFTVVASDSA 876
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G + I T+ I D +D P + I ENS +G + + +TD+ +
Sbjct: 877 GNSTEQAI---TLDITDLDDVAPTITSSVTATAIDENSGVGQVVYT---VTSTDSGDIAT 930
Query: 823 ALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII 881
+ Y+L G+ +F ++ +TG V + D E K Y ++VA DT G SSE + +
Sbjct: 931 GVTAYSLKAGDDAALFTINSSTGAVTLTANP-DDETKADYSFTVVATDTAGNSSEQVITL 989
Query: 882 MIGDENDNKP 891
I D ++ P
Sbjct: 990 DITDLDEVAP 999
Score = 51.6 bits (118), Expect = 2e-04
Identities = 49/192 (25%), Positives = 82/192 (42%), Gaps = 9/192 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ ALD +SG GQ+ Y S ++ + S A + F IN
Sbjct: 1303 LDEVAPTITSASSATALDENSGA-GQVVYTVTSTDSGDIATGATAYSLKASDDAALFTIN 1361
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + + ES ++ + A DG + ++ + + D++D P
Sbjct: 1362 SSTGAVTLTANPDDESKADYNFTVVASDGAGNSTEQAITLDIIDLDDVAPTITSASSAIA 1421
Query: 1054 VEEAQYTRRVLGKVDATD-ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
++E +V+ V +TD D A TY ++ D F I+ TG +++ D E+
Sbjct: 1422 LDENSGAGQVVYTVTSTDNGDIATGAT-TYSLKAGDDAALFTINSSTGAVTLTANPDDES 1480
Query: 1113 EDKYILTVVARD 1124
+ Y TVVA D
Sbjct: 1481 KADYNFTVVASD 1492
Score = 50.4 bits (115), Expect = 4e-04
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 7/192 (3%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ + +D +SG +GQ+ Y +S++ + S A + F IN
Sbjct: 582 LDEVAPTITSASTASTIDENSG-SGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNIN 640
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + E+ ++ + A D + ++ + + D++D P
Sbjct: 641 SSTGAVTLTADPDDETKADYNFTVLASDAAGNSREQAITLDIIDLDDVAPTITSASSATA 700
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
++E +V+ V +TD+D + + Y ++ D F I+ TG ++++ + D ET+
Sbjct: 701 LDENSGAGQVVYTVTSTDSDDVSSGSTDYSLKTGDDAALFTINSSTGAVTLSADPDDETK 760
Query: 1114 DKYILTVVARDN 1125
Y TVVA D+
Sbjct: 761 ADYNFTVVASDS 772
Score = 49.6 bits (113), Expect = 6e-04
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 9/187 (4%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKRYFVINERHGH 1000
P T+ ALD +SG GQ+ Y N ++ + S A + F IN G
Sbjct: 1411 PTITSASSAIALDENSGA-GQVVYTVTSTDNGDIATGATTYSLKAGDDAALFTINSSTGA 1469
Query: 1001 VIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
V + + ES ++ + A DG + ++ + + D+++ P+ ++E
Sbjct: 1470 VTLTANPDDESKADYNFTVVASDGAGNSSEKAITLDITDLDEVGPIITSASSATALDENS 1529
Query: 1059 YTRRVLGKVDATD-ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+V+ V +TD D A TY ++ D F I+ TG +++ + D E++ Y
Sbjct: 1530 GAGQVVYTVTSTDNGDIATGAT-TYSLKSGDDVALFTINSSTGAVTLTADPDDESKADYN 1588
Query: 1118 LTVVARD 1124
TVVA D
Sbjct: 1589 FTVVASD 1595
Score = 49.6 bits (113), Expect = 6e-04
Identities = 45/193 (23%), Positives = 80/193 (41%), Gaps = 7/193 (3%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ A+D +SG GQ+ Y S ++ + S A++ F IN
Sbjct: 1715 LDEVAPTITSASSATAIDENSGA-GQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTIN 1773
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + + E+ ++ + A D N +V + + D+++ P
Sbjct: 1774 STSGAVTLTANPNDETKADYNFTVVATDSPGNNSEKAVTLDITDLDEIAPTITSAATATA 1833
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
++E +V+ V +TD+ Y ++ D F I+ TG +++ D ET+
Sbjct: 1834 IDENSGAGQVVYTVTSTDSGDVAIGATVYSLKTGDDAALFTINSSTGAVTLTANPDDETK 1893
Query: 1114 DKYILTVVARDNG 1126
Y VVA D G
Sbjct: 1894 ADYSFIVVATDTG 1906
Score = 47.6 bits (108), Expect = 0.003
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 9/187 (4%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVINERHGH 1000
P T+ ALD +SG GQ+ Y S ++ + S A + F IN G
Sbjct: 1205 PTITSATTATALDENSGA-GQVVYTVTSTDSGDIATGVTVYSLKAGDDAALFTINSSSGA 1263
Query: 1001 VIVARSLPPES--EFRLNISALDG-GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V + + ES ++ + A DG GN ++ ++ + + D+++ P ++E
Sbjct: 1264 VTLTANPDDESKADYNFTVVASDGAGNSSEKVTT-LDITDLDEVAPTITSASSATALDEN 1322
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+V+ V +TD+ Y ++ SD F I+ TG +++ D E++ Y
Sbjct: 1323 SGAGQVVYTVTSTDSGDIATGATAYSLKASDDAALFTINSSTGAVTLTANPDDESKADYN 1382
Query: 1118 LTVVARD 1124
TVVA D
Sbjct: 1383 FTVVASD 1389
Score = 46.8 bits (106), Expect = 0.005
Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT Y L +G+D LF+++S G++ L D D E N VL A+
Sbjct: 618 DITTGAT-SYSLKAGDDAALFNINSSTGAVTLTA--DPDDETKADYNFTVLASDAAG--- 671
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ + + ++++DL+D P ++ EN G V V +TD D +G Y
Sbjct: 672 --NSREQAITLDIIDLDDVAPTITSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTDY 729
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 730 SLKTGDDAALFTINSSTGAVTL 751
Score = 46.0 bits (104), Expect = 0.008
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 4/136 (2%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNISALD-GGNLNDNISVRVFVKDVNDHFPVFKKT 1048
F IN G VI+ + ES ++ + A D GN+++ SV + D+++ P
Sbjct: 534 FAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQ-SVTFDITDLDEVAPTITSA 592
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
++E + +V+ V +TD+ +Y ++ D F I+ TG +++ +
Sbjct: 593 STASTIDENSGSGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNINSSTGAVTLTADP 652
Query: 1109 DRETEDKYILTVVARD 1124
D ET+ Y TV+A D
Sbjct: 653 DDETKADYNFTVLASD 668
Score = 45.2 bits (102), Expect = 0.014
Identities = 44/191 (23%), Positives = 79/191 (41%), Gaps = 7/191 (3%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ ALD +SG GQ+ Y S ++ + S + F IN
Sbjct: 788 LDEVAPTITSTAIAAALDENSGA-GQVVYTVTSTDSGDIATGATAYSLKIGDDAALFTIN 846
Query: 996 ERHGHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + + E+ ++ + A D + ++ + + D++D P +
Sbjct: 847 SGTGEVTLIANPDDETKADYNFTVVASDSAGNSTEQAITLDITDLDDVAPTITSSVTATA 906
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
++E +V+ V +TD+ Y ++ D F I+ TG +++ D ET+
Sbjct: 907 IDENSGVGQVVYTVTSTDSGDIATGVTAYSLKAGDDAALFTINSSTGAVTLTANPDDETK 966
Query: 1114 DKYILTVVARD 1124
Y TVVA D
Sbjct: 967 ADYSFTVVATD 977
Score = 45.2 bits (102), Expect = 0.014
Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 9/192 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ ALD +SG GQ+ Y S ++ + S + F IN
Sbjct: 994 LDEVAPTITSASSATALDENSGA-GQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTIN 1052
Query: 996 ERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + + E +++ + A D + S+ + + D+++ P
Sbjct: 1053 SSTGAVTLTANPDDEIRADYNFTVVATDTAGNSREQSITLDITDLDEVAPTITSASIAAA 1112
Query: 1054 VEEAQYTRRVLGKVDATD-ADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
++E +V+ V +TD D A + Y ++ D F I+ TG +++ D E+
Sbjct: 1113 IDENSGASQVVYTVTSTDNGDIATGATV-YSLKAGDDAALFTINSSTGAVTLTANPDDES 1171
Query: 1113 EDKYILTVVARD 1124
+ Y TVVA D
Sbjct: 1172 KADYNFTVVASD 1183
Score = 44.4 bits (100), Expect = 0.024
Identities = 44/187 (23%), Positives = 81/187 (43%), Gaps = 9/187 (4%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNS----EVYIPPSKLSADALEVKRYFVINERHGH 1000
P T+ + A+D +SG+ GQ+ Y S ++ + S A + F IN G
Sbjct: 896 PTITSSVTATAIDENSGV-GQVVYTVTSTDSGDIATGVTAYSLKAGDDAALFTINSSTGA 954
Query: 1001 VIVARSLPPES--EFRLNISALD-GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
V + + E+ ++ + A D GN ++ + + + + D+++ P ++E
Sbjct: 955 VTLTANPDDETKADYSFTVVATDTAGNSSEQV-ITLDITDLDEVAPTITSASSATALDEN 1013
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI 1117
+V+ V +TD+ Y ++ SD F I+ TG +++ D E Y
Sbjct: 1014 SGAGQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTINSSTGAVTLTANPDDEIRADYN 1073
Query: 1118 LTVVARD 1124
TVVA D
Sbjct: 1074 FTVVATD 1080
Score = 44.0 bits (99), Expect = 0.032
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT Y L SG+D LF+++S G++ L D D E N V V + N
Sbjct: 1545 DIATGATT-YSLKSGDDVALFTINSSTGAVTLTA--DPDDESKADYNFTV--VASDGAGN 1599
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+++ + ++++DL++ P +I EN G V VM+TD TY
Sbjct: 1600 ---SSEKAITLDIIDLDEVAPTITSAAIAAAIDENSGAGQVVYTVMSTDNGDIATDATTY 1656
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 1657 SLKSGDDAALFTINSSTGAVTL 1678
Score = 44.0 bits (99), Expect = 0.032
Identities = 45/193 (23%), Positives = 83/193 (43%), Gaps = 9/193 (4%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKRYFVIN 995
+ E P T+ A+D +SG GQ+ Y N ++ + S + + F IN
Sbjct: 1612 LDEVAPTITSAAIAAAIDENSGA-GQVVYTVMSTDNGDIATDATTYSLKSGDDAALFTIN 1670
Query: 996 ERHGHVIVARSLPPESEFRLNIS--ALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
G V + + E + N + A DG + ++ + + D+++ P
Sbjct: 1671 SSTGAVTLTANPDDEGKANYNFTVVASDGAGNSSEKAITLDITDLDEVAPTITSASSATA 1730
Query: 1054 VEEAQYTRRVLGKVDATDA-DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
++E +V+ V +TD+ D A L Y ++ D F I+ +G +++ + ET
Sbjct: 1731 IDENSGAGQVVYTVTSTDSGDIATGATL-YSLKAVDDAALFTINSTSGAVTLTANPNDET 1789
Query: 1113 EDKYILTVVARDN 1125
+ Y TVVA D+
Sbjct: 1790 KADYNFTVVATDS 1802
Score = 42.7 bits (96), Expect = 0.075
Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT Y L + +D LF+++S G++ L + D E N V V + N
Sbjct: 1339 DIATGATA-YSLKASDDAALFTINSSTGAVTLTA--NPDDESKADYNFTV--VASDGAGN 1393
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
T QA + ++++DL+D P I++ EN G V V +TD G TY
Sbjct: 1394 --STEQA-ITLDIIDLDDVAPTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTY 1450
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 1451 SLKAGDDAALFTINSSTGAVTL 1472
Score = 42.3 bits (95), Expect = 0.099
Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT+ Y L +G+D LF+++S G++ L + D E N V+ A+ N
Sbjct: 1133 DIATGATV-YSLKAGDDAALFTINSSTGAVTL--TANPDDESKADYNFTVVASDAA--GN 1187
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
T QA + +++ DL+D P ++ EN G V V +TD G Y
Sbjct: 1188 --STEQA-ITLDITDLDDVAPTITSATTATALDENSGAGQVVYTVTSTDSGDIATGVTVY 1244
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ SG +T+
Sbjct: 1245 SLKAGDDAALFTINSSSGAVTL 1266
Score = 41.9 bits (94), Expect = 0.13
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 7/187 (3%)
Query: 945 PIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD-ALEV---KRYFVINERHGH 1000
P T+ ALD +SG GQ+ Y S S S D +L+ F IN G
Sbjct: 690 PTITSASSATALDENSGA-GQVVYTVTSTDSDDVSSGSTDYSLKTGDDAALFTINSSTGA 748
Query: 1001 VIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQ 1058
V ++ E+ ++ + A D + ++ + + D+++ P T ++E
Sbjct: 749 VTLSADPDDETKADYNFTVVASDSAGNSTEQAITLDIIDLDEVAPTITSTAIAAALDENS 808
Query: 1059 YTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYIL 1118
+V+ V +TD+ Y ++ D F I+ TG +++ D ET+ Y
Sbjct: 809 GAGQVVYTVTSTDSGDIATGATAYSLKIGDDAALFTINSGTGEVTLIANPDDETKADYNF 868
Query: 1119 TVVARDN 1125
TVVA D+
Sbjct: 869 TVVASDS 875
Score = 41.1 bits (92), Expect = 0.23
Identities = 57/235 (24%), Positives = 98/235 (41%), Gaps = 22/235 (9%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GATL Y L + +D LF+++S +G++ L + + + + F + S NN
Sbjct: 1751 DIATGATL-YSLKAVDDAALFTINSTSGAVTLTANPNDETKADYN---FTVVATDSPGNN 1806
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
K V +++ DL++ P +I EN G V V +TD G Y
Sbjct: 1807 SEKA----VTLDITDLDEIAPTITSAATATAIDENSGAGQVVYTVTSTDSGDVAIGATVY 1862
Query: 344 QL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIA 401
L D F+I+ +G +T+ D E + V A +T + S+++
Sbjct: 1863 SLKTGDDAALFTINSSTGAVTLTANP--DDETKADYSFIVVATDTGNN------SSEQVV 1914
Query: 402 KWRRQPLETNAPLEKTTYVFPDKVGTKTENIEY---YDEQLMSFVNVEVTLLDAN 453
L+ AP+ + V D K+E + E + +F N ++ L AN
Sbjct: 1915 TLDINDLDEVAPIINSV-VLSDTDLAKSETATLTITFSEAVTNFTNDDIDLTSAN 1968
Score = 39.9 bits (89), Expect = 0.53
Identities = 40/142 (28%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ G+T Y L +G+D LF+++S G++ L D D E N V V + N
Sbjct: 721 DVSSGST-DYSLKTGDDAALFTINSSTGAVTL--SADPDDETKADYNFTV--VASDSAGN 775
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
T QA + ++++DL++ P ++ EN G V V +TD G Y
Sbjct: 776 --STEQA-ITLDIIDLDEVAPTITSTAIAAALDENSGAGQVVYTVTSTDSGDIATGATAY 832
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 833 SLKIGDDAALFTINSGTGEVTL 854
Score = 39.9 bits (89), Expect = 0.53
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 12/165 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT Y L G+D LF+++S G + L D + + + F + S N+
Sbjct: 824 DIATGATA-YSLKIGDDAALFTINSGTGEVTLIANPDDETKADYN---FTVVASDSAGNS 879
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
T QA + +++ DL+D P +I EN G V V +TD G Y
Sbjct: 880 ---TEQA-ITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAY 935
Query: 344 QL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
L D F+I+ +G +T+ D E + V A +T
Sbjct: 936 SLKAGDDAALFTINSSTGAVTLTANP--DDETKADYSFTVVATDT 978
Score = 39.1 bits (87), Expect = 0.92
Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ AT Y L SG+D LF+++S G++ L D + + N + V AS +
Sbjct: 1648 DIATDATT-YSLKSGDDAALFTINSSTGAVTLTANPDDEGKAN-----YNFTVVAS--DG 1699
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+++ + +++ DL++ P +I EN G V V +TD G Y
Sbjct: 1700 AGNSSEKAITLDITDLDEVAPTITSASSATAIDENSGAGQVVYTVTSTDSGDIATGATLY 1759
Query: 344 QLD--DPKGAFSIDPRSGWLTV 363
L D F+I+ SG +T+
Sbjct: 1760 SLKAVDDAALFTINSTSGAVTL 1781
Score = 37.1 bits (82), Expect = 3.7
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ GAT Y L +G+D LF+++S G++ L D +++ + + V AS +
Sbjct: 1442 DIATGATT-YSLKAGDDAALFTINSSTGAVTLTANPDDESKAD-----YNFTVVAS--DG 1493
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+++ + +++ DL++ P ++ EN G V V +TD G TY
Sbjct: 1494 AGNSSEKAITLDITDLDEVGPIITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTY 1553
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 1554 SLKSGDDVALFTINSSTGAVTL 1575
Score = 36.3 bits (80), Expect = 6.5
Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 12/165 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ G T Y L +G+D LF+++S G++ L D + + + +F + V N
Sbjct: 927 DIATGVTA-YSLKAGDDAALFTINSSTGAVTLTANPDDETKADY---SFTV-VATDTAGN 981
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+++ + +++ DL++ P ++ EN G V V +TD G Y
Sbjct: 982 ---SSEQVITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAY 1038
Query: 344 QL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
L D F+I+ +G +T+ D E + V A +T
Sbjct: 1039 SLKTSDDAALFTINSSTGAVTLTANP--DDEIRADYNFTVVATDT 1081
Score = 36.3 bits (80), Expect = 6.5
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 10/142 (7%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D+ G T+ Y L +G+D LF+++S +G++ L D +++ + T V A +
Sbjct: 1236 DIATGVTV-YSLKAGDDAALFTINSSSGAVTLTANPDDESKADYNF-TVVASDGAGNSSE 1293
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ T +++ DL++ P ++ EN G V V +TD G Y
Sbjct: 1294 KVTT------LDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAY 1347
Query: 344 QL--DDPKGAFSIDPRSGWLTV 363
L D F+I+ +G +T+
Sbjct: 1348 SLKASDDAALFTINSSTGAVTL 1369
>UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens
"Protocadherin 20; n=2; Clupeocephala|Rep: Homolog of
Homo sapiens "Protocadherin 20 - Takifugu rubripes
Length = 406
Score = 91.9 bits (218), Expect = 1e-16
Identities = 95/355 (26%), Positives = 149/355 (41%), Gaps = 31/355 (8%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP------FAVEE 624
P F + + N GT + ++ D + + + Y E VP F ++
Sbjct: 51 PQFTESQINVTLHGNASKGTHLARLHAFDP--DLGANAQISYAYSERVPKDTRSLFHLDR 108
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+GVI + Y +A N I AT+HV+D ND V K S +
Sbjct: 109 ITGVIKLARKTDTGTATFYKLTVLA---NGPGCIPAVATIHVLDENDNAPVFEK---SLV 162
Query: 685 IFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE--DGTIFTQ 741
+ EN S + Q+ T+ S G G V +L+ +I I + G +
Sbjct: 163 KISIDENNSPNTFLAQLQATDQDS---EGRGEVIYLLGGD---APEIFILDRVTGVLIVA 216
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
LDRE+++ YR V A ++G I V + ++D NDN P F + + F+ EN
Sbjct: 217 ASLDREEKETYRFIVRA-VDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFP 275
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
EI +I TDAD G N ++ G + F +D G ++ SLDRE++ Y
Sbjct: 276 GYGEI---GVISVTDADAGENGWVALSIIN-GSDTFMIDTGRGTLR-AKTSLDREQQGTY 330
Query: 862 KLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
+L + A D G LS + +++ D NDN P + N + L GT+
Sbjct: 331 QLWIEAADGGEPALSCITMITVLLLDVNDNPPTVLFPQSNQSYMLVLPNTLPGTS 385
Score = 88.6 bits (210), Expect = 1e-15
Identities = 97/395 (24%), Positives = 161/395 (40%), Gaps = 25/395 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L+ +++ + D NDN P F S + ++ NA GT + ++ A DPDLG N + Y
Sbjct: 33 LLGAATLKIVIADVNDNCPQFTESQI-NVTLHGNASKGTHLARLHAFDPDLGANAQISYA 91
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
S F ++ TG + +A + A F + + P AV TI
Sbjct: 92 YSERVPKDTRSLFHLDRITGVIKLARK--TDTGTATFYKLTVLANGPG---CIPAVATIH 146
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
V + P F + + + N T + Q++ D + L G +
Sbjct: 147 VL----DENDNAPVFEKSLVKISIDENNSPNTFLAQLQATDQDSEGRGEVIYLLGGDAPE 202
Query: 619 PFAVEERSGVITVVDDLSRYNRPMYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLL 677
F ++ +GV+ V L R + Y F A+ Q + + V D ND L
Sbjct: 203 IFILDRVTGVLIVAASLDREEKETYRFIVRAVDQGTPRRESIATVVLTVQDRNDNSPRFL 262
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
+ F V EN G G+I +++ G V I N D + GT
Sbjct: 263 ---NKDFTFFVPENFPG--YGEIGVISVTDADAGENGWVALSIINGSDTF--MIDTGRGT 315
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP--VFEHATYE-G 794
+ + LDRE++ Y++ + A + G + + I +T+ + D NDNPP +F +
Sbjct: 316 LRAKTSLDREQQGTYQLWIEAA-DGGEPALSCITMITVLLLDVNDNPPTVLFPQSNQSYM 374
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
++ N+ GT I + A D D G NA+ Y++
Sbjct: 375 LVLPNTLPGTSI---TEVYAVDRDTGMNAVIAYSI 406
Score = 75.8 bits (178), Expect = 9e-12
Identities = 81/315 (25%), Positives = 127/315 (40%), Gaps = 30/315 (9%)
Query: 943 NIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVI 1002
N GT + +L+A D D G N QI Y ++ V P + + F ++ G +
Sbjct: 65 NASKGTHLARLHAFDPDLGANAQISYAYSERV---PK-------DTRSLFHLDRITGVIK 114
Query: 1003 VARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR 1062
+AR + ++ L G + V D ND+ PVF+K+ +++E
Sbjct: 115 LARKTDTGTATFYKLTVLANGPGCIPAVATIHVLDENDNAPVFEKSLVKISIDENNSPNT 174
Query: 1063 VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVA 1122
L ++ ATD D + Y + D F + +TGVL V LDRE ++ Y V A
Sbjct: 175 FLAQLQATDQDSEGRGEVIYLL-GGDAPEIFILDRVTGVLIVAASLDREEKETYRFIVRA 233
Query: 1123 RDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVY 1182
D G D NDNSP+F D + PE + + + +I V
Sbjct: 234 VDQG-TPRRESIATVVLTVQDRNDNSPRFLNKD--FTFFVPE----NFPGYGEIGVISVT 286
Query: 1183 KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNL----------GLPSL 1232
A EN + ++ + +DT I G G + + QQ G P+L
Sbjct: 287 DADAGENGWVALSI--INGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPAL 344
Query: 1233 SSTAILMVTVADVPD 1247
S ++ V + DV D
Sbjct: 345 SCITMITVLLLDVND 359
Score = 73.3 bits (172), Expect = 5e-11
Identities = 107/419 (25%), Positives = 178/419 (42%), Gaps = 64/419 (15%)
Query: 1001 VIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
VIV +L E+ E+ +I A DGG L ++++ + DVND+ P F ++ N +
Sbjct: 5 VIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHG 64
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETE 1113
L ++ A D D G NA ++Y P DT F + +TGV+ + + D T
Sbjct: 65 NASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRSLFHLDRITGVIKLARKTDTGTA 124
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y LTV+A G D NDN+P F++ L DE ++ N
Sbjct: 125 TFYKLTVLANGPG-----CIPAVATIHVLDENDNAP---VFEKSL--VKISIDENNSPN- 173
Query: 1174 ESVMMIPVYKATIEENAPIGTTVAKVFANDTD-FI---GNGNGLILYSLPQRKNQQ---- 1225
+ +AT +++ G + + + + FI G ++ SL + + +
Sbjct: 174 ---TFLAQLQATDQDSEGRGEVIYLLGGDAPEIFILDRVTGVLIVAASLDREEKETYRFI 230
Query: 1226 ----NLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENV--NAPVELVSL 1279
+ G P S A +++TV D D + P F+++ + + EN + ++S+
Sbjct: 231 VRAVDQGTPRRESIATVVLTVQDRND-----NSPRFLNKDFTFFVPENFPGYGEIGVISV 285
Query: 1280 NLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQK 1339
+ EN + I+N +D TF+ID GTL S DRE + TY++ + A
Sbjct: 286 TDADAGENGWVALSIINGSD-----TFMIDTGRGTLRAKTSLDREQQGTYQLWIEAA--- 337
Query: 1340 YSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK--FTNGNRPLVTAIPTTAP 1396
E L +T + V + DVNDN P F N+ + +P T P
Sbjct: 338 ----------DGGEPALSCIT----MITVLLLDVNDNPPTVLFPQSNQSYMLVLPNTLP 382
Score = 68.9 bits (161), Expect = 1e-09
Identities = 83/334 (24%), Positives = 135/334 (40%), Gaps = 31/334 (9%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEK-AFIFLIAP- 123
D++ G + ++ + I DVNDN P F ++ +VT+ G A + P
Sbjct: 22 DIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHGNASKGTHLARLHAFDPD 81
Query: 124 IGPSLTIPLTVPRGLTIFKDIRAF---DR--------DKPNTPNSDVHYSIVSGNDDGHF 172
+G + I + KD R+ DR K +T + + V N G
Sbjct: 82 LGANAQISYAYSERVP--KDTRSLFHLDRITGVIKLARKTDTGTATFYKLTVLANGPGCI 139
Query: 173 ALESSHKPVLLLRKVLDYDAGDKEFQL-VIMASGKRIHKEILFPEPIHAIDQDLGVGATL 231
P + VLD + F+ ++ S + F + A DQD +
Sbjct: 140 -------PAVATIHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQATDQDSEGRGEV 192
Query: 232 RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
Y L+ G+ ++F LD V G L + LD + + T+ V+A P + + A
Sbjct: 193 IY-LLGGDAPEIFILDRVTGVLIVAASLDRE-----EKETYRFIVRAVDQGTPRRESIAT 246
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
V + + D NDN P F + + EN P + + TD D GENG + +
Sbjct: 247 VVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGENGWVALSIINGSDT 306
Query: 352 FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
F ID G T+R +T LDRE + ++ + A +
Sbjct: 307 FMIDTGRG--TLRAKTSLDREQQGTYQLWIEAAD 338
Score = 61.7 bits (143), Expect = 2e-07
Identities = 74/289 (25%), Positives = 117/289 (40%), Gaps = 30/289 (10%)
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
LT + V LDRET+ +YI ++A D G DVNDN P+F ++
Sbjct: 1 LTPFVIVTDALDRETQAEYITDIIAEDGG-TPPLLGAATLKIVIADVNDNCPQF-TESQI 58
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
H A + H + + + + NA I ++ DT + + + +
Sbjct: 59 NVTLHGNASK-GTH----LARLHAFDPDLGANAQISYAYSERVPKDTRSLFHLDRITGVI 113
Query: 1218 LPQRKNQQNLG----LPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
RK L L++ + VA + E + PVF ++ I+EN +
Sbjct: 114 KLARKTDTGTATFYKLTVLANGPGCIPAVATIHVLDENDNAPVFEKSLVKISIDENNSPN 173
Query: 1274 VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIV 1333
L L T+ ++ + R ++ D F++D G L + S DRE K+TY IV
Sbjct: 174 TFLAQLQATD--QDSEGRGEVIYLLGGDAPEIFILDRVTGVLIVAASLDREEKETYRFIV 231
Query: 1334 RAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTN 1382
RA Q R E + VV+ ++D NDNSP+F N
Sbjct: 232 RAVDQGTPRR---------ESI--------ATVVLTVQDRNDNSPRFLN 263
Score = 55.2 bits (127), Expect = 1e-05
Identities = 74/282 (26%), Positives = 119/282 (42%), Gaps = 39/282 (13%)
Query: 84 TVYIEDVNDNVPIFLDTPYHVTVDE----------LTPT-----GEKAFIFLIAPIGPSL 128
T+++ D NDN P+F + +++DE L T G I+L+ P +
Sbjct: 144 TIHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQATDQDSEGRGEVIYLLGGDAPEI 203
Query: 129 TIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVL 188
I L G+ I + DR++ T + IV D G ES VL ++
Sbjct: 204 FI-LDRVTGVLIVA--ASLDREEKET-----YRFIVRAVDQGTPRRESIATVVLTVQDRN 255
Query: 189 DYDAG--DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL 246
D +K+F + + + EI I D D G + +I+G+D F +
Sbjct: 256 DNSPRFLNKDFTFFVPENFPG-YGEI---GVISVTDADAGENGWVALSIINGSDT--FMI 309
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
D+ G+L + LD + Q T+ L ++A+ P + + + LLD+NDN P
Sbjct: 310 DTGRGTLRAKTSLDRE-----QQGTYQLWIEAADGGEPALSCITMITVLLLDVNDNPPTV 364
Query: 307 EVDFYNISIVENLPN---GFSVLQVMATDKDQGENGEFTYQL 345
N S + LPN G S+ +V A D+D G N Y +
Sbjct: 365 LFPQSNQSYMLVLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406
Score = 42.3 bits (95), Expect = 0.099
Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
++ + A P A ++I + D+NDN P+F N+++ N G + ++ A
Sbjct: 19 YITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHGNASKGTHLARLHAF 78
Query: 332 DKDQGENGEFTYQLD-----DPKGAFSIDPRSGWLTVRNQT 367
D D G N + +Y D + F +D +G + + +T
Sbjct: 79 DPDLGANAQISYAYSERVPKDTRSLFHLDRITGVIKLARKT 119
Score = 38.3 bits (85), Expect = 1.6
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEEN 899
+ D+LDRE + Y ++A D G L A L I+I D NDN P+F + + N
Sbjct: 7 VTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQIN 59
>UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12;
Amniota|Rep: Protocadherin alpha C1 precursor - Homo
sapiens (Human)
Length = 963
Score = 91.9 bits (218), Expect = 1e-16
Identities = 114/469 (24%), Positives = 195/469 (41%), Gaps = 30/469 (6%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V + ++D NDN PVF S +Y + A GTV+ +V+A+DPD G NG V Y L ++
Sbjct: 219 VTIIVVDTNDNAPVFERS-VYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQ 277
Query: 505 LTITSPFKINPNTGTVSVAES-PILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
+ F ++P +G V VA S E ++EA D+ S A + +EVT
Sbjct: 278 AELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLA---STAKLLVEVT-DV 333
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF--- 620
+ P++ DF+ V + GT + V D E D + ++ G PF
Sbjct: 334 NDHAPEL-DFLTLSNP--VPEDAAPGTVIALFSVKD--EDLDSNGRVICGMSSAGPFQLT 388
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKG 679
A + + + L R Y A + LS TV V DVND +
Sbjct: 389 ASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQP 448
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL--IANQQDVTDDIAI-AEDG 736
+F + N GA++G++F + + NG + L I+ + +A+ + G
Sbjct: 449 QQE--LFVAENNGPGASLGRVFAQD-PDLGKNGLVSYELLDVISEGPSASSLLAVESSSG 505
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
I + D E+ + V + G+ + + +++ D NDN PV
Sbjct: 506 AITAKTSFDFEQLRGFHFQVEGR-DGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGS 564
Query: 797 MENSKIGTEIKMDNIIK---ATDADEGTNALFMYTLF-GEGKEMFDVDENTGVVKFIGDS 852
+ + + +++ A DAD G+NA Y + +F + N G ++
Sbjct: 565 VPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGELRTARLV 624
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN-KPEFNQIEE 898
L + + ++ +V RD G LSS L +++ + P+F + E
Sbjct: 625 LPTD-AVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWE 672
Score = 81.0 bits (191), Expect = 2e-13
Identities = 69/241 (28%), Positives = 116/241 (48%), Gaps = 21/241 (8%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+HV+D ND + G + H+ E A + N G + + ++
Sbjct: 112 IHVLDTNDNSPLFPAG---DVQLHIPEFLTPGA--RFTLPNAQDDDEGSNGILSYSLSPS 166
Query: 724 QDVTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
Q D+ DG+ + +K LDRE+R + + + A + G+ + +G QVTI + D
Sbjct: 167 QHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTAR-DGGLPARSGDAQVTIIVVD 225
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKE 835
NDN PVFE + Y + E + GT + ++A D DEG+N Y+L E +
Sbjct: 226 TNDNAPVFERSVYRTKVPETAPNGTVLFR---VQALDPDEGSNGEVQYSLSNSTQAELRH 282
Query: 836 MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
F V +G V+ + SL + ++ + + ARD G GL+S A+L++ + D ND+ PE
Sbjct: 283 RFHVHPKSGEVQ-VAASLGPPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPEL 340
Query: 894 N 894
+
Sbjct: 341 D 341
Score = 77.4 bits (182), Expect = 3e-12
Identities = 64/218 (29%), Positives = 95/218 (43%), Gaps = 20/218 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE P GT + ++ ALD D G NG+++Y ++ S A E++ F ++ + G
Sbjct: 242 VPETAPNGTVLFRVQALDPDEGSNGEVQYSLSN---------STQA-ELRHRFHVHPKSG 291
Query: 1000 HVIVARSL-PPESEFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
V VA SL PPE+ I A D G L + V V DVNDH P + V E
Sbjct: 292 EVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPE 351
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETE 1113
V+ D D N + + + PF+++ L ++G LDRE
Sbjct: 352 DAAPGTVIALFSVKDEDLDSNGRVICGMSSAG---PFQLTASFDNYYSLLIDGPLDREQI 408
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y + + A D+G DVNDN+P F
Sbjct: 409 SEYQVLITASDSG-SPPLSTRRTITVSVADVNDNTPNF 445
Score = 76.2 bits (179), Expect = 7e-12
Identities = 63/242 (26%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 689 KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREK 748
+E G A+G + + N RFL ++ +++ + + G + ++P DRE+
Sbjct: 28 EETERGVAVGNLSADLRLPAAAMSSRNFRFL-SSHRELYFGVDLPS-GNLVVREPADREQ 85
Query: 749 RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKM 808
+ + ++ + ++++ I++ D NDN P+F + I E G +
Sbjct: 86 LCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTL 145
Query: 809 DNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF----IGDSLDREKKIMYKLS 864
N A D DEG+N + Y+L D+ ++ + +LDRE++ + L
Sbjct: 146 PN---AQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLV 202
Query: 865 LVARDTGGL---SSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEV 921
L ARD GGL S +A++ I++ D NDN P F + +KV ET NGT F + +
Sbjct: 203 LTARD-GGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKV---PETAPNGTVLFRVQAL 258
Query: 922 KP 923
P
Sbjct: 259 DP 260
Score = 73.7 bits (173), Expect = 3e-11
Identities = 108/473 (22%), Positives = 183/473 (38%), Gaps = 39/473 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + + + +LD NDN+P+F P+ + + G A D D G NG++
Sbjct: 102 EDPLELHKIRIHVLDTNDNSPLF-PAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILS 160
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASD--QPANPSERRYS 551
Y L + + + +++ + V E + H L + A D PA + + +
Sbjct: 161 YSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVT 220
Query: 552 LAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYD 609
+ VV T N P F + Y V GT + +++ D E +V Y
Sbjct: 221 IIVV------DTNDN---APVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYS 271
Query: 610 LLHGYEEGV--PFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVV 667
L + + + F V +SG + V L + + + L+ V V
Sbjct: 272 LSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVT 331
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
DVND L + V E++A + +F + NG A +T
Sbjct: 332 DVNDHAPEL---DFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLT 388
Query: 728 DDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF 787
+ ++ PLDRE+ Y++ + A + G + +T+ + D NDN P F
Sbjct: 389 --ASFDNYYSLLIDGPLDREQISEYQVLITAS-DSGSPPLSTRRTITVSVADVNDNTPNF 445
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL---FGEG---KEMFDVDE 841
E F+ EN+ G + + A D D G N L Y L EG + V+
Sbjct: 446 PQPQQELFVAENNGPGASL---GRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVES 502
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGGL---SSEAELIIMIGDENDNKP 891
++G + S D E+ + + RD GG+ S+ + + + D NDN P
Sbjct: 503 SSGAIT-AKTSFDFEQLRGFHFQVEGRD-GGIPPRSATVTINLFVVDRNDNYP 553
Score = 73.3 bits (172), Expect = 5e-11
Identities = 49/150 (32%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
+A D D G L Y L +L V+GS + E L+ + +A T +L + A
Sbjct: 147 NAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRA-THLLVLTA 205
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P ++ A+V I ++D NDN P FE Y + E PNG + +V A D D+G N
Sbjct: 206 RDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSN 265
Query: 339 GEFTYQLDDPKGA-----FSIDPRSGWLTV 363
GE Y L + A F + P+SG + V
Sbjct: 266 GEVQYSLSNSTQAELRHRFHVHPKSGEVQV 295
Score = 61.3 bits (142), Expect = 2e-07
Identities = 71/291 (24%), Positives = 120/291 (41%), Gaps = 29/291 (9%)
Query: 73 GLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPL 132
GL S VT+ + D NDN P+F + Y V E P G +F + + P
Sbjct: 209 GLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNG--TVLFRVQALDPDEGSNG 266
Query: 133 TVPRGLT--IFKDIRAFDRDKPNTPNSDVHYSI----------VSGNDDGHFALESSHKP 180
V L+ ++R P + V S+ + D+G F L S+ K
Sbjct: 267 EVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAK- 325
Query: 181 VLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAI----DQDLGVGATLRYELI 236
LL +V D + E + +++ E P + A+ D+DL + +
Sbjct: 326 --LLVEVTDVNDHAPELDFLTLSNPV---PEDAAPGTVIALFSVKDEDLDSNGRVICGMS 380
Query: 237 SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIEL 296
S +L + SL ++ LD + Q + + + + AS +P + + + + +
Sbjct: 381 SAGPFQLTASFDNYYSLLIDGPLDRE-----QISEYQVLITASDSGSPPLSTRRTITVSV 435
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
D+NDN P F + + EN G S+ +V A D D G+NG +Y+L D
Sbjct: 436 ADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLD 486
Score = 58.0 bits (134), Expect = 2e-06
Identities = 87/351 (24%), Positives = 139/351 (39%), Gaps = 40/351 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPE + G NA D D G NG + Y + + +L + V +
Sbjct: 133 IPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHF---RLDMGSR------VDGSEYP 183
Query: 1000 HVIVARSLPPESEFR--LNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+++ ++L E L ++A DGG + + V + V D ND+ PVF+++ Y V
Sbjct: 184 ELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVP 243
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPS-DTDL--PFEISPLTGVLSVNGELDRET 1112
E VL +V A D D G N + Y + S +L F + P +G + V L
Sbjct: 244 ETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PP 302
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHN 1172
E + ARD G DVND++P+ + L +P ++ +
Sbjct: 303 ETLLEAYIEARDEG-VFGLASTAKLLVEVTDVNDHAPEL----DFLTLSNPVPEDAAPGT 357
Query: 1173 FESVMMIPVYKATIEENAPI--GTTVAKVFANDTDFIGNGNGLILYSLPQRK-------- 1222
+ + V ++ N + G + A F F + LI L + +
Sbjct: 358 V--IALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLI 415
Query: 1223 NQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAP 1273
+ G P LS+ + V+VADV D + P F EL + EN N P
Sbjct: 416 TASDSGSPPLSTRRTITVSVADVND-----NTPNFPQPQQELFVAEN-NGP 460
Score = 50.0 bits (114), Expect = 5e-04
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 19/200 (9%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
LF+ N P G ++ ++ A D D G NG + YE + PS S A+E
Sbjct: 452 LFVAENNGP-GASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVE--------S 502
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
G + S E F + DGG + +++ +FV D ND++PV
Sbjct: 503 SSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRN 562
Query: 1053 N------VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNG 1106
V + T ++ KV A DAD G NA L+Y I + F IS G L
Sbjct: 563 GSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGELRTAR 622
Query: 1107 ELDRETEDKYILTVVARDNG 1126
+ K + VV RD+G
Sbjct: 623 LVLPTDAVKQRVVVVVRDHG 642
Score = 49.2 bits (112), Expect = 9e-04
Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 18/199 (9%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
++EV N A ++D L +PE+ GT I + D D NG++ +S
Sbjct: 327 LVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSA---G 383
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRV 1033
P +L+A + + +++ L E SE+++ I+A D G+ L+ ++ V
Sbjct: 384 PFQLTASF----------DNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITV 433
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPF 1093
V DVND+ P F + V E LG+V A D D G+N ++Y + ++ P
Sbjct: 434 SVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGP- 492
Query: 1094 EISPLTGVLSVNGELDRET 1112
S L V S +G + +T
Sbjct: 493 SASSLLAVESSSGAITAKT 511
Score = 45.2 bits (102), Expect = 0.014
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
+ +S + F +D +G+L + + D E +A + L +PL+ + R+
Sbjct: 55 FRFLSSHRELYFGVDLPSGNLVVREPAD--REQLCRAKAACVLTYDLVLEDPLELHKIRI 112
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF 352
+ LD NDN P F + I E L G A D D+G NG +Y L P F
Sbjct: 113 HV--LDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSL-SPSQHF 169
Query: 353 SID 355
+D
Sbjct: 170 RLD 172
Score = 42.7 bits (96), Expect = 0.075
Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 5/125 (4%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-- 1088
+R+ V D ND+ P+F ++ E +A D D G N L+Y + PS
Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHF 169
Query: 1089 -TDLPFEISPLT-GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVND 1146
D+ + L + LDRE ++L + ARD G D ND
Sbjct: 170 RLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGG-LPARSGDAQVTIIVVDTND 228
Query: 1147 NSPKF 1151
N+P F
Sbjct: 229 NAPVF 233
Score = 40.7 bits (91), Expect = 0.30
Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 16/139 (11%)
Query: 218 IHAIDQDLGVGATLRYELIS-----GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D DLG + YEL+ + L +++S +G++ + D + Q F
Sbjct: 467 VFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFE-----QLRGF 521
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLP----NGFSVL 326
QV+ P ++A + + ++D NDN P F + VE +P G V
Sbjct: 522 HFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVT 581
Query: 327 QVMATDKDQGENGEFTYQL 345
+V+A D D G N +Y +
Sbjct: 582 KVVAEDADSGSNAWLSYHI 600
Score = 39.1 bits (87), Expect = 0.92
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 8/86 (9%)
Query: 443 VNVEVTLLDANDNNPVF---VPSN--LYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
V + + ++D NDN PV +P N + + +A+ G ++ KV A D D G N + Y
Sbjct: 539 VTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSY 598
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVA 523
+ R S+ +S F+I+ N G + A
Sbjct: 599 HISRASD---SSLFRISANIGELRTA 621
>UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio
"Cadherin-related neuronal receptor variable 7.; n=1;
Takifugu rubripes|Rep: Homolog of Brachydanio rerio
"Cadherin-related neuronal receptor variable 7. -
Takifugu rubripes
Length = 718
Score = 91.5 bits (217), Expect = 2e-16
Identities = 121/502 (24%), Positives = 213/502 (42%), Gaps = 62/502 (12%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+E E + N+EV LLD NDN P F ++ + G AVDPD+G
Sbjct: 8 LEVILENPLRIFNIEVELLDINDNAPQFRRDAIH-LDISEATPRGERFSLSNAVDPDIGS 66
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSER 548
N + Y L I + ++ + + H L + A D P+
Sbjct: 67 NSVKTYQLSENDYFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDG-GKPA-- 123
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
R A V + V T N P F Y + N IG+ V + D E ++
Sbjct: 124 RSGTASVIVHVM-DTNDNSPT---FDQINYNLEIMENSPIGSLVIHLNATDLDEGSNS-- 177
Query: 609 DLLHGYEEGVPF-AVEERSGVITVVD-----DLSRYNRPMYDFEAV------ALQENANL 656
DL + Y G+ + +R + ++ D+++ +Y E + + + + L
Sbjct: 178 DLTYSYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYL 237
Query: 657 SI---------VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS 707
+ + N V ++D+ND + I H+ + S G+ F + +
Sbjct: 238 KLEVILDSPVRIFNIEVEILDINDNAPQFRRD-----IIHL-DISEATPRGERFSLSNAV 291
Query: 708 IYGNGTGNVR-FLIANQQDVTDDIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNK 762
G+ +V+ + ++ + ++ DG+ F++ + LDRE++ V+ + ++ +
Sbjct: 292 DPDVGSNSVKTYYLSESEYFNIEVQTGRDGSKFSELILKRALDREQQSVHNL-ILTAVDG 350
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G + +G V + + D NDN P F+ + Y IMENS IG+ + + ATD DEG+N
Sbjct: 351 GKPARSGTASVIVRVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIH---LNATDLDEGSN 407
Query: 823 A--LFMYTLFGEGK--EMFDVDENTGVVKFIG-------DSLDREKKIMYKLSLVARDTG 871
+ + Y+L+ K E F ++ +TG + G D E + + + ARD+G
Sbjct: 408 SDLTYSYSLYTAEKTQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSG 467
Query: 872 G--LSSEAELIIMIGDENDNKP 891
LSS + I+I D+NDN P
Sbjct: 468 SPPLSSNVSVHIIIVDQNDNAP 489
Score = 88.6 bits (210), Expect = 1e-15
Identities = 95/344 (27%), Positives = 140/344 (40%), Gaps = 48/344 (13%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+GTA I+ V N + DQ+ I EN PIG+ +I LNA DLD G N + Y +
Sbjct: 125 SGTAS-VIVHVMDTNDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSY 183
Query: 971 NSEVYIP---PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLND 1027
N + + K+ D + K+Y +N+ G + V + E S +
Sbjct: 184 NLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEVIL 243
Query: 1028 NISVRVF-----VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
+ VR+F + D+ND+ P F++ + ++ EA +A D D G N+ TY
Sbjct: 244 DSPVRIFNIEVEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVKTY 303
Query: 1083 FIQPSDTDLPFEISPLTG-------VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXX 1135
++ S+ F I TG L + LDRE + + L + A D G
Sbjct: 304 YLSESEY---FNIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGG-KPARSGTA 359
Query: 1136 XXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTT 1195
D NDNSP F + SN+N E I EN+PIG+
Sbjct: 360 SVIVRVLDTNDNSPTF---------------DKSNYNLE-----------IMENSPIGSL 393
Query: 1196 VAKVFANDTDFIGNGNGLILYSL-PQRKNQQNLGL-PSLSSTAI 1237
V + A D D N + YSL K Q+ L PS +
Sbjct: 394 VIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEITV 437
Score = 73.7 bits (173), Expect = 3e-11
Identities = 67/228 (29%), Positives = 101/228 (44%), Gaps = 17/228 (7%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+GTA I+ V N + D+ I EN PIG+ +I LNA DLD G N + Y +
Sbjct: 356 SGTAS-VIVRVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSY 414
Query: 971 N---SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--L 1025
+ +E L+ E+ ++N + + E EF +I A D G+ L
Sbjct: 415 SLYTAEKTQETFYLNPSTGEITVKGLLNYEDFKIY---DMEIEKEFLFHIEARDSGSPPL 471
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTW-YNFNVEEAQYTR-----RVLGKVDATDADFGQNAN 1079
+ N+SV + + D ND+ PV W +V E + R ++ KV A D D N+
Sbjct: 472 SSNVSVHIIIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSR 531
Query: 1080 LTY-FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
+TY +Q +D L F + G + L VVA+DNG
Sbjct: 532 ITYQLLQVTDATL-FSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDNG 578
Score = 70.5 bits (165), Expect = 3e-10
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 10/153 (6%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQV 276
+A+D D+G + Y L + +GS F E L LD E N + V
Sbjct: 289 NAVDPDVGSNSVKTYYLSESEYFNIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAV 348
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ P ++ A V + +LD NDN P F+ YN+ I+EN P G V+ + ATD D+G
Sbjct: 349 DGGK---PARSGTASVIVRVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEG 405
Query: 337 ENGEFTYQ-----LDDPKGAFSIDPRSGWLTVR 364
N + TY + + F ++P +G +TV+
Sbjct: 406 SNSDLTYSYSLYTAEKTQETFYLNPSTGEITVK 438
Score = 66.9 bits (156), Expect = 4e-09
Identities = 65/225 (28%), Positives = 98/225 (43%), Gaps = 25/225 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E P G NA+D D G N Y Y+ S+ ++ R +
Sbjct: 275 ISEATPRGERFSLSNAVDPDVGSNSVKTY------YLSESEYFNIEVQTGRD---GSKFS 325
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+I+ R+L E + L ++A+DGG + SV V V D ND+ P F K+ YN +
Sbjct: 326 ELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTFDKSNYNLEIM 385
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY---FIQPSDTDLPFEISPLTGVLSVNGEL---- 1108
E ++ ++ATD D G N++LTY T F ++P TG ++V G L
Sbjct: 386 ENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEITVKGLLNYED 445
Query: 1109 ----DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
D E E +++ + ARD+G D NDN+P
Sbjct: 446 FKIYDMEIEKEFLFHIEARDSG-SPPLSSNVSVHIIIVDQNDNAP 489
Score = 64.9 bits (151), Expect = 2e-08
Identities = 39/127 (30%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQV 276
+A+D D+G + Y+L + + G+ F + L LD E N + V
Sbjct: 58 NAVDPDIGSNSVKTYQLSENDYFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAV 117
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ P ++ A V + ++D NDN P F+ YN+ I+EN P G V+ + ATD D+G
Sbjct: 118 DGGK---PARSGTASVIVHVMDTNDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEG 174
Query: 337 ENGEFTY 343
N + TY
Sbjct: 175 SNSDLTY 181
Score = 60.9 bits (141), Expect = 3e-07
Identities = 76/309 (24%), Positives = 134/309 (43%), Gaps = 37/309 (11%)
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
EQ V +L + G P S ++ V+D + N P +D Q N NL I+ N
Sbjct: 105 EQQSVHNLILTAVDGGKPARSGTASVIVHVMD--TNDNSPTFD------QINYNLEIMEN 156
Query: 662 ATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ + + ++ L +G++S + + + G + + N + + N ++L
Sbjct: 157 SPIGSLVIHLNATDLDEGSNSDLTYSY---NLGLDVKTL---NQRKMRLDIIANKKYLDV 210
Query: 722 NQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
N+ E G ++ + +DRE + + + + S I+ + + I D N
Sbjct: 211 NK----------ETGELYVVEKIDREYICSTKASCYLKLEVILDSPVRIFNIEVEILDIN 260
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DN P F I E + G + N A D D G+N++ Y L E F+++
Sbjct: 261 DNAPQFRRDIIHLDISEATPRGERFSLSN---AVDPDVGSNSVKTYYL--SESEYFNIEV 315
Query: 842 NTGV--VKF----IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEF 893
TG KF + +LDRE++ ++ L L A D G S A +I+ + D NDN P F
Sbjct: 316 QTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTF 375
Query: 894 NQIEENSKV 902
++ N ++
Sbjct: 376 DKSNYNLEI 384
Score = 56.8 bits (131), Expect = 4e-06
Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 22/241 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V V +LD NDN+P F SN Y + N+ +G+++ + A D D G N + Y +
Sbjct: 360 SVIVRVLDTNDNSPTFDKSN-YNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYT 418
Query: 504 NLTITSPFKINPNTGTVSV------AESPI----LEGRHALFVEASDQPANPSERRYSLA 553
F +NP+TG ++V + I +E +EA D + P S+
Sbjct: 419 AEKTQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVH 478
Query: 554 VVTIEVTRGTKGNKPDIPD---FMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSY 608
++ ++ N P I G+ E + + G+ V ++ D+ + ++Y
Sbjct: 479 IIIVD----QNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITY 534
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
LL + F++++ +G I + S Y P + V ++N N ++ T+ +
Sbjct: 535 QLLQ-VTDATLFSLDQYNGEIRTMRMFS-YRDPRHQRLVVVAKDNGNPALSATVTIKLST 592
Query: 669 V 669
V
Sbjct: 593 V 593
Score = 56.0 bits (129), Expect = 7e-06
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
L NPL+ +E+ELLD+NDN P+F D ++ I E P G A D D G N
Sbjct: 12 LENPLRIFN--IEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSV 69
Query: 341 FTYQLDDPKGAFSIDPRSG-----WLTVRNQTVLDREAHS 375
TYQL + F+I+ ++G + + +T LDRE S
Sbjct: 70 KTYQLSE-NDYFNIEVQTGREGTKFADLILKTTLDREQQS 108
Score = 56.0 bits (129), Expect = 7e-06
Identities = 35/129 (27%), Positives = 73/129 (56%), Gaps = 7/129 (5%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+R ++I+ ++K ++ G L++ +++D + + +A+ + L+++ L++P++
Sbjct: 197 MRLDIIA--NKKYLDVNKETGELYVVEKIDREYICSTKASCY-LKLEVI-LDSPVRIFN- 251
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+E+E+LD+NDN P+F D ++ I E P G A D D G N TY L + +
Sbjct: 252 -IEVEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVKTYYLSESE- 309
Query: 351 AFSIDPRSG 359
F+I+ ++G
Sbjct: 310 YFNIEVQTG 318
Score = 54.0 bits (124), Expect = 3e-05
Identities = 103/411 (25%), Positives = 164/411 (39%), Gaps = 69/411 (16%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
++ V + D+ND+ P F++ + ++ EA +A D D G N+ TY Q S+
Sbjct: 20 NIEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTY--QLSEN 77
Query: 1090 DLPFEISPLTG-------VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
D F I TG L + LDRE + + L + A D G
Sbjct: 78 DY-FNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDGG-KPARSGTASVIVHVM 135
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
D NDNSP FD++ N+N E I EN+PIG+ V + A
Sbjct: 136 DTNDNSP---TFDQI------------NYNLE-----------IMENSPIGSLVIHLNAT 169
Query: 1203 DTDFIGNGNGLILYSL---PQRKNQQNLGLPSLSSTAILMVT-VADVPDEVEMSDKPVFI 1258
D D N + Y+L + NQ+ + L +++ L V VE D+
Sbjct: 170 DLDEGSNSDLTYSYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELYVVEKIDREYIC 229
Query: 1259 SRYYE--LEIEENVNAPV-----ELVSLNLTEHYENFKMRYYILNENDTDIR-----RTF 1306
S L++E +++PV E+ L++ ++ F+ L+ ++ R +
Sbjct: 230 STKASCYLKLEVILDSPVRIFNIEVEILDINDNAPQFRRDIIHLDISEATPRGERFSLSN 289
Query: 1307 VIDPRNG-----TLYLVRS--------PDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
+DP G T YL S R+ E+I++ + + + H + A
Sbjct: 290 AVDPDVGSNSVKTYYLSESEYFNIEVQTGRDGSKFSELILKRALDREQQSV-HNLILTAV 348
Query: 1354 DVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQL 1404
D + V+VR+ D NDNSP F N L I +P G V+ L
Sbjct: 349 DGGKPARSGTASVIVRVLDTNDNSPTFDKSNYNL--EIMENSPIGSLVIHL 397
Score = 48.8 bits (111), Expect = 0.001
Identities = 73/338 (21%), Positives = 134/338 (39%), Gaps = 31/338 (9%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
N+EV +LD NDN P F ++ + G AVDPD+G N + Y L +
Sbjct: 251 NIEVEILDINDNAPQF-RRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVKTYYLSESE 309
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
I + + + + + + + H L + A D P+ R A V + V
Sbjct: 310 YFNIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVD-GGKPA--RSGTASVIVRVL 366
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYDLLHGYEE 616
T N P F + Y + N IG+ V + D E ++ SY L +
Sbjct: 367 -DTNDNS---PTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKT 422
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEA-------VALQENANLSIVTNATVH--VV 667
F + +G ITV L+ + +YD E + +++ + + +N +VH +V
Sbjct: 423 QETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHIIIV 482
Query: 668 DVNDERGVLLK--GAHSPIIFH--VKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
D ND V++ A ++ + G+ + ++ ++ S++ + + + +
Sbjct: 483 DQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS---RITYQLLQV 539
Query: 724 QDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFN 761
D T +G I T + R+ V+A+ N
Sbjct: 540 TDATLFSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDN 577
Score = 44.4 bits (100), Expect = 0.024
Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 12/160 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFV-----PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V+V + ++D NDN PV V ++ E + + G+++ KV A+D D N
Sbjct: 471 LSSNVSVHIIIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 530
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLA 553
+ Y L + ++ T+ S + N T+ + + RH V + NP+ A
Sbjct: 531 RITYQLLQVTDATLFSLDQYNGEIRTMRMFS--YRDPRHQRLVVVAKDNGNPA----LSA 584
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG 593
VTI+++ K D P E+ + S++ + +G
Sbjct: 585 TVTIKLSTVETAVKA-YSDLTEVPLEYDIFSDLNLYLVIG 623
Score = 35.9 bits (79), Expect = 8.6
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 16/153 (10%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P+ S TA ++V V D D + P F Y LEI EN ++ LN T+ E
Sbjct: 351 GKPARSGTASVIVRVLDTND-----NSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEG 405
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N + Y + TF ++P G + + + E Y++ + E
Sbjct: 406 SNSDLTYSYSLYTAEKTQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKE--------- 456
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
+ + A D +V V + I D NDN+P
Sbjct: 457 FLFHIEARDSGSPPLSSNVSVHIIIVDQNDNAP 489
>UniRef50_Q4T0W5 Cluster: Chromosome 1 SCAF10821, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF10821, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 303
Score = 91.5 bits (217), Expect = 2e-16
Identities = 57/159 (35%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + K LDRE++ ++ + A + G +G + + + D NDN PVF A Y
Sbjct: 95 GELVLDKELDREEQKEIKLKLTA-VDGGSPQRSGTVVIHVTVLDANDNAPVFSQALYSAT 153
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMY---TLFGEGKEMFDVDENTGVVKFIGDS 852
+ ENS I T + + ATDADEG N Y + K MF ++++TG + G+
Sbjct: 154 LSENSPINTPV---IAVSATDADEGVNGEVTYEFSRISERSKNMFSLNQHTGEITVTGE- 209
Query: 853 LDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+D E Y++ + A+D GLSSEA++II I D NDN P
Sbjct: 210 IDYEDGQKYEIFVEAKDGYGLSSEAKVIIDITDVNDNTP 248
Score = 76.6 bits (180), Expect = 5e-12
Identities = 51/162 (31%), Positives = 82/162 (50%), Gaps = 9/162 (5%)
Query: 997 RHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNF 1052
++G +++ + L E E +L ++A+DGG+ + + + V V D ND+ PVF + Y+
Sbjct: 93 KYGELVLDKELDREEQKEIKLKLTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQALYSA 152
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSD-TDLPFEISPLTGVLSVNGELDR 1110
+ E + V ATDAD G N +TY F + S+ + F ++ TG ++V GE+D
Sbjct: 153 TLSENSPINTPVIAVSATDADEGVNGEVTYEFSRISERSKNMFSLNQHTGEITVTGEIDY 212
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
E KY + V A+D DVNDN+P Y
Sbjct: 213 EDGQKYEIFVEAKDG---YGLSSEAKVIIDITDVNDNTPVIY 251
Score = 70.9 bits (166), Expect = 2e-10
Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 11/139 (7%)
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
G L L+KELD + + ++ L++ A +P ++ + + +LD NDN P F
Sbjct: 95 GELVLDKELDREEQKEIK-----LKLTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQAL 149
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL----DDPKGAFSIDPRSGWLTVRNQ 366
Y+ ++ EN P V+ V ATD D+G NGE TY+ + K FS++ +G +TV +
Sbjct: 150 YSATLSENSPINTPVIAVSATDADEGVNGEVTYEFSRISERSKNMFSLNQHTGEITVTGE 209
Query: 367 TVLDREAHSSLRMKVYAKE 385
+D E + V AK+
Sbjct: 210 --IDYEDGQKYEIFVEAKD 226
Score = 66.5 bits (155), Expect = 5e-09
Identities = 41/117 (35%), Positives = 64/117 (54%), Gaps = 4/117 (3%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V + VT+LDANDN PVF + LY ++ N+ + T + V A D D G NG V Y+ R
Sbjct: 129 VVIHVTVLDANDNAPVFSQA-LYSATLSENSPINTPVIAVSATDADEGVNGEVTYEFSRI 187
Query: 503 SNLTITSPFKINPNTGTVSV-AESPILEG-RHALFVEASDQPANPSERRYSLAVVTI 557
S + + F +N +TG ++V E +G ++ +FVEA D SE + + + +
Sbjct: 188 SERS-KNMFSLNQHTGEITVTGEIDYEDGQKYEIFVEAKDGYGLSSEAKVIIDITDV 243
Score = 57.2 bits (132), Expect = 3e-06
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 14/121 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN PI T +I ++A D D G+NG++ YEF S++S + K F +N+ G
Sbjct: 154 LSENSPINTPVIAVSATDADEGVNGEVTYEF--------SRISERS---KNMFSLNQHTG 202
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPV-FKKTWYNFNVEE 1056
+ V + E ++ + + A DG L+ V + + DVND+ PV + K+ N E+
Sbjct: 203 EITVTGEIDYEDGQKYEIFVEAKDGYGLSSEAKVIIDITDVNDNTPVIYVKSLKNTVPED 262
Query: 1057 A 1057
A
Sbjct: 263 A 263
Score = 41.1 bits (92), Expect = 0.23
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 27/153 (17%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLTEHY 1285
G P S T ++ VTV D D PVF Y + EN +N PV VS +
Sbjct: 121 GSPQRSGTVVIHVTVLDANDNA-----PVFSQALYSATLSENSPINTPVIAVSATDADEG 175
Query: 1286 ENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++ Y ++ + F ++ G + + D E YE+ V A + Y
Sbjct: 176 VNGEVTYEFSRISERS-KNMFSLNQHTGEITVTGEIDYEDGQKYEIFVEA-KDGY----- 228
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
G++ + KV++ I DVNDN+P
Sbjct: 229 ------------GLSS-EAKVIIDITDVNDNTP 248
Score = 36.7 bits (81), Expect = 4.9
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D GV + YE IS + +FSL+ G + + E+D E + FV
Sbjct: 167 VSATDADEGVNGEVTYEFSRISERSKNMFSLNQHTGEITVTGEIDY--EDGQKYEIFVEA 224
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVEN 318
L++ +A+V I++ D+NDN P V ++ E+
Sbjct: 225 KDGYGLSS-----EAKVIIDITDVNDNTPVIYVKSLKNTVPED 262
>UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep:
Pf1-cadherin - Ptychodera flava
Length = 1959
Score = 91.5 bits (217), Expect = 2e-16
Identities = 81/269 (30%), Positives = 123/269 (45%), Gaps = 21/269 (7%)
Query: 707 SIYGNGT-GNVRFLIANQQDVTDDIAIA-EDGTIFTQKPLDRE--KRDVYRMTVIAEFNK 762
++ NG N+++ I Q + +D AI G I ++K LDRE K V TV A +
Sbjct: 489 TVRANGDPSNIQYRI-QQAEFREDFAIGLTSGIISSRKHLDREDNKGQVREFTVTASNSA 547
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
G S +V I I+D NDN P F + Y G EN G + D +EG N
Sbjct: 548 GTTS----VEVLIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGN 603
Query: 823 ALFMYTLFGE-----GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA 877
AL Y++ G+ +F +D + V+ +LDRE+ Y + + A D G +
Sbjct: 604 ALVRYSILRNAQNSVGQAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGAHTGTV 663
Query: 878 ELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK---NKFALDVDQL 934
I + DENDN PEF Q + S V I ++ + F +I + N +++ +
Sbjct: 664 TATIYVSDENDNPPEFPQAK--SFVEISENVPVDSSV-FKVIAIDRDVGINSYSIISGNV 720
Query: 935 GPLFLIPENIPIGTTIIKLNALDLDSGLN 963
G F I + G I+K+ A +D LN
Sbjct: 721 GEKFRIETDPDSGYAIVKV-AKKIDFELN 748
Score = 72.5 bits (170), Expect = 8e-11
Identities = 109/475 (22%), Positives = 183/475 (38%), Gaps = 41/475 (8%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDL 499
V V + + D NDN P F P Y S N G + ++A D P+ G N +V Y +
Sbjct: 552 VEVLIKIKDVNDNAPQF-PYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSI 610
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
R + ++ + V + L+ + + D + VT +
Sbjct: 611 LRNAQNSVGQAIFAIDSESAVITTQVGNLDREE---IPSYDIVVKAVDGGAHTGTVTATI 667
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP 619
+ + P P+F A + NV + +SV ++ D + SY ++ G G
Sbjct: 668 YVSDENDNP--PEFPQAKSFVEISENVPVDSSVFKVIAIDR-DVGINSYSIISG-NVGEK 723
Query: 620 FAVE-ERSGVITVVDDLSRYNRPMYDFEAVALQE--NANLSIVTNATVHVVDVNDERGVL 676
F +E + +V + + + + + V E ++ + T + V+D NDE
Sbjct: 724 FRIETDPDSGYAIVKVAKKIDFELNESKFVLTIEVDDSKNTATTELDIRVMDANDEVPSF 783
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---A 733
+ + + H ++ + IG + T+ + F + + D +
Sbjct: 784 SQPRY--LAEHPEDFAKWTTIGTVAATDRDK--SEKFSEIEFEVVRVPEFPDSSFFTVGS 839
Query: 734 EDGTIFTQKPLDREK-------RDVYRMTVIAEFNKGVISG----AGIYQVTIYIEDEND 782
+G++ K LDRE R+ Y TV A N SG T+ I D ND
Sbjct: 840 ANGSVMAIKDLDREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFTVSITDVND 899
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK--EMFDVD 840
N P F Y + EN+ G E + II D G F + + + FDV
Sbjct: 900 NAPEFLPG-YTLLVPENTPAGYEAGVVEIIDRDDDSNGPP--FTHRVIDDDGILSFFDVS 956
Query: 841 ENTGV---VKFIG-DSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
GV ++ + + DRE Y + +V D G+S+ L + IGD NDN P
Sbjct: 957 SPIGVEDQLRVVSLEEFDREATPFYYIPVVLSDKHGVSATQTLTVTIGDVNDNPP 1011
Score = 70.9 bits (166), Expect = 2e-10
Identities = 52/174 (29%), Positives = 83/174 (47%), Gaps = 13/174 (7%)
Query: 725 DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+V + EDG I + + L ++ + V+ +F + A IYI DN
Sbjct: 58 EVASLFGVTEDGIIRSMEELTDYANRMFSV-VVEQF---LDDDAWKDSFNIYITKSGDNS 113
Query: 785 P--VFEHATYEGFIMENSKIGTEIK-MDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
F YEG ++ENS GT + ++I ++ D L Y+L G G+E F+++
Sbjct: 114 EHLKFTQDRYEGSVLENSPAGTVVYGFESISACSECD-----LVEYSLLGTGEEKFNLEN 168
Query: 842 NTGVVKF-IGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFN 894
G+V + LDRE + Y L+LVA + +L+I + D NDN PEF+
Sbjct: 169 KDGIVTIQTNEVLDRESRASYNLTLVAASASLETETTDLLITVEDVNDNAPEFD 222
Score = 65.7 bits (153), Expect = 9e-09
Identities = 77/286 (26%), Positives = 118/286 (41%), Gaps = 22/286 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKG 679
FA+ SG+I+ L R + E N+ + + + DVND
Sbjct: 512 FAIGLTSGIISSRKHLDREDNKGQVREFTVTASNSAGTTSVEVLIKIKDVNDNAPQF--- 568
Query: 680 AHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAIA---E 734
+ P I EN A G + I ++ G VR+ ++ N Q+ A E
Sbjct: 569 PYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSE 628
Query: 735 DGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISGA--GIYQVTIYIEDENDNPPVFEHAT 791
I TQ LDRE+ Y + V K V GA G TIY+ DENDNPP F A
Sbjct: 629 SAVITTQVGNLDREEIPSYDIVV-----KAVDGGAHTGTVTATIYVSDENDNPPEFPQA- 682
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTG--VVKFI 849
+ F+ + + + + +I A D D G N+ + + K + D ++G +VK +
Sbjct: 683 -KSFVEISENVPVDSSVFKVI-AIDRDVGINSYSIISGNVGEKFRIETDPDSGYAIVK-V 739
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQ 895
+D E + + D ++ EL I + D ND P F+Q
Sbjct: 740 AKKIDFELNESKFVLTIEVDDSKNTATTELDIRVMDANDEVPSFSQ 785
Score = 60.1 bits (139), Expect = 5e-07
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 6/133 (4%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+ Y L+ + K F+L++ +G + ++ LD E N ++ AS L+T
Sbjct: 152 VEYSLLGTGEEK-FNLENKDGIVTIQTNEVLDRESRASYNLTLVAASAS-----LETETT 205
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+ I + D+NDN PEF+ + +++ E P V V A D D G+NG+ Y D
Sbjct: 206 DLLITVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMYYTDTNDM 265
Query: 351 AFSIDPRSGWLTV 363
FS+ P +G + +
Sbjct: 266 TFSVHPDTGGVII 278
Score = 56.8 bits (131), Expect = 4e-06
Identities = 99/394 (25%), Positives = 153/394 (38%), Gaps = 44/394 (11%)
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEE---AQYTRRVLGKVDATDADFGQNANLTYFI 1084
++ V + +KDVND+ P F Y + E T + D D + G NA + Y I
Sbjct: 551 SVEVLIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSI 610
Query: 1085 ----QPSDTDLPFEISPLTGVLSVN-GELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
Q S F I + V++ G LDRE Y + V A D G
Sbjct: 611 LRNAQNSVGQAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGAHTGTVTATIYVS 670
Query: 1140 XXXDVNDNSPKF---YAFDELLE--------WKHPEADELSNHNFESVMMIPV-YKATIE 1187
D NDN P+F +F E+ E +K D N S++ V K IE
Sbjct: 671 ---DENDNPPEFPQAKSFVEISENVPVDSSVFKVIAIDRDVGINSYSIISGNVGEKFRIE 727
Query: 1188 ENAPIGTTVAKVFANDTDFIGNGNGLIL-YSLPQRKNQQNLGLPSLSSTAILMVTVADVP 1246
+ G + KV A DF N + +L + KN ++T L + V D
Sbjct: 728 TDPDSGYAIVKV-AKKIDFELNESKFVLTIEVDDSKN---------TATTELDIRVMDAN 777
Query: 1247 DEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTF 1306
DEV +P +++ + E + V + +E + ++ + ++ + F
Sbjct: 778 DEVPSFSQPRYLAEHPEDFAKWTTIGTVAATDRDKSEKFS--EIEFEVVRVPEFPDSSFF 835
Query: 1307 VIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKV 1366
+ NG++ ++ DRE + + I R+ Y + V E V
Sbjct: 836 TVGSANGSVMAIKDLDREPYEDPDQI----RENYIFTVT-ATDNVRGQSGERRNTATVTF 890
Query: 1367 VVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQ 1400
V I DVNDN+P+F G LV P P GY+
Sbjct: 891 TVSITDVNDNAPEFLPGYTLLV---PENTPAGYE 921
Score = 56.4 bits (130), Expect = 6e-06
Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 15/195 (7%)
Query: 1011 SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ + L + A + + + V+DVND+ P F V E ++ V A
Sbjct: 187 ASYNLTLVAASASLETETTDLLITVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAV 246
Query: 1071 DADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXX 1130
D D G+N + Y+ + D+ F + P TG + + G L + +Y LTV ARD G
Sbjct: 247 DPDAGKNGKVMYYTDTN--DMTFSVHPDTGGVIIGGPLQAK---EYTLTVFARDRGKPSL 301
Query: 1131 XXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENA 1190
D S KF + P L + + E +P K ++ E+A
Sbjct: 302 EASTPGRVIITVTPVDQSLKFSSI------LGPGPVILQDDDEE----LPEIKVSLMEDA 351
Query: 1191 PIGTTVAKVFANDTD 1205
P G+ V + A D
Sbjct: 352 PKGSVVTTIKAPSND 366
Score = 54.4 bits (125), Expect = 2e-05
Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 22/167 (13%)
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
GTG +F + N+ + TI T + LDRE R Y +T++A
Sbjct: 158 GTGEEKFNLENKDGIV---------TIQTNEVLDRESRASYNLTLVAA---SASLETETT 205
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+ I +ED NDN P F+ T E + E S + + A D D G N MY +
Sbjct: 206 DLLITVEDVNDNAPEFDPETCEVTVPEISPADAIVA---YVHAVDPDAGKNGKVMY--YT 260
Query: 832 EGKEM-FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEA 877
+ +M F V +TG V IG L ++ Y L++ ARD G S EA
Sbjct: 261 DTNDMTFSVHPDTGGV-IIGGPLQAKE---YTLTVFARDRGKPSLEA 303
Score = 54.0 bits (124), Expect = 3e-05
Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQA--NTFVLQVQAS-----QLNNPLKTAQARV 292
D F++ S NGS+ K+LD + + ++ V A+ Q TA
Sbjct: 831 DSSFFTVGSANGSVMAIKDLDREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTF 890
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-EFTYQLDDPKGA 351
+ + D+NDN PEF + Y + + EN P G+ V D+D NG FT+++ D G
Sbjct: 891 TVSITDVNDNAPEF-LPGYTLLVPENTPAGYEAGVVEIIDRDDDSNGPPFTHRVIDDDGI 949
Query: 352 FSIDPRSGWLTVRNQ 366
S S + V +Q
Sbjct: 950 LSFFDVSSPIGVEDQ 964
Score = 53.2 bits (122), Expect = 5e-05
Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 8/114 (7%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+T+ D NDN P F P E ++ + ++ V AVDPD G+NG V+Y T+++T
Sbjct: 209 ITVEDVNDNAPEFDPETC-EVTVPEISPADAIVAYVHAVDPDAGKNGKVMY-YTDTNDMT 266
Query: 507 ITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F ++P+TG V + P+ + L V A D+ PS + V I VT
Sbjct: 267 ----FSVHPDTGGVIIG-GPLQAKEYTLTVFARDR-GKPSLEASTPGRVIITVT 314
Score = 52.8 bits (121), Expect = 7e-05
Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 6/118 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
AID+D+G+ + Y +ISGN + F +++ S + ++ + L + FVL ++
Sbjct: 703 AIDRDVGINS---YSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELNESKFVLTIEVD 759
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
N TA ++I ++D ND +P F Y E+ ++ V ATD+D+ E
Sbjct: 760 DSKN---TATTELDIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVAATDRDKSE 814
Score = 52.0 bits (119), Expect = 1e-04
Identities = 75/285 (26%), Positives = 120/285 (42%), Gaps = 38/285 (13%)
Query: 898 ENSKVRIHRET-KLNGTAGFTIIEVKPKNKFALDVDQLGPLF-------LIPENIPIGTT 949
E++K ++ T + +AG T +EV K K DV+ P F PEN G T
Sbjct: 530 EDNKGQVREFTVTASNSAGTTSVEVLIKIK---DVNDNAPQFPYPPYIGSFPENGAPGVT 586
Query: 950 IIKLNALDLDS---GLNGQIRYEF--NSEVYIPPSKLSADALEVKRYFVINERHGHVIVA 1004
++ + A DLD G N +RY N++ + + + D+ VI + G+ +
Sbjct: 587 VMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSESA----VITTQVGN-LDR 641
Query: 1005 RSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVL 1064
+P + + + A+DGG ++ ++V D ND+ P F + + E +
Sbjct: 642 EEIP---SYDIVVKAVDGGAHTGTVTATIYVSDENDNPPEFPQAKSFVEISENVPVDSSV 698
Query: 1065 GKVDATDADFGQNANLTYFIQPSDTDLPF--EISPLTG--VLSVNGELDRE-TEDKYILT 1119
KV A D D G N +Y I + F E P +G ++ V ++D E E K++LT
Sbjct: 699 FKVIAIDRDVGIN---SYSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELNESKFVLT 755
Query: 1120 VVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPE 1164
+ D+ D ND P F L E HPE
Sbjct: 756 IEVDDS----KNTATTELDIRVMDANDEVPSFSQPRYLAE--HPE 794
Score = 51.6 bits (118), Expect = 2e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 27/299 (9%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
IE D + + +++ ++DAND P F + AK T IG V A D D +
Sbjct: 756 IEVDDSKNTATTELDIRVMDANDEVPSFSQPRYLAEHPEDFAK-WTTIGTVAATDRDKSE 814
Query: 492 N-GMVLYDLQRTSNLTITSPFKINPNTGTVSVA--------ESPILEGRHALF-VEASDQ 541
+ +++ R +S F + G+V E P + +F V A+D
Sbjct: 815 KFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDLDREPYEDPDQIRENYIFTVTATDN 874
Query: 542 PANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND-- 599
S R + A VT V+ T N + P+F+ Y V N G G + + D
Sbjct: 875 VRGQSGERRNTATVTFTVSI-TDVN-DNAPEFLPG-YTLLVPENTPAGYEAGVVEIIDRD 931
Query: 600 ------AFEQNDVSYD-LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE 652
F + D +L ++ P VE++ V++ +++ R P Y + V L +
Sbjct: 932 DDSNGPPFTHRVIDDDGILSFFDVSSPIGVEDQLRVVS-LEEFDREATPFY-YIPVVLSD 989
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGN 711
+S TV + DVND + +++ K +AIG+++ + + G+
Sbjct: 990 KHGVSATQTLTVTIGDVNDNPP--SPATKTILVYSYKGQIPRSAIGEVYAADEDIVKGD 1046
Score = 48.0 bits (109), Expect = 0.002
Identities = 96/373 (25%), Positives = 141/373 (37%), Gaps = 44/373 (11%)
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----- 605
S ++EV K + P F PY N G +V I+ D + N+
Sbjct: 546 SAGTTSVEVLIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNAL 605
Query: 606 VSYDLLHGYEEGVP---FAVEERSGVITV-VDDLSRYNRPMYDFEAVALQENANLSIVTN 661
V Y +L + V FA++ S VIT V +L R P YD A+ A+ VT
Sbjct: 606 VRYSILRNAQNSVGQAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGAHTGTVT- 664
Query: 662 ATVHVVDVNDERGVLLKG-AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
AT++V D ND + + I +V +S+ + I + Y +GNV
Sbjct: 665 ATIYVSDENDNPPEFPQAKSFVEISENVPVDSSVFKVIAIDRDVGINSYSIISGNVGEKF 724
Query: 721 ANQQDVTDDIAIAEDGTIFTQKPLDREKRDV-YRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ D AI + K +D E + + +T+ + +K + ++ I + D
Sbjct: 725 RIETDPDSGYAIVK-----VAKKIDFELNESKFVLTIEVDDSKNTATT----ELDIRVMD 775
Query: 780 ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG---TNALFMYTLFGE--GK 834
ND P F Y E+ T I + ATD D+ + F E
Sbjct: 776 ANDEVPSFSQPRYLAEHPEDFAKWTTI---GTVAATDRDKSEKFSEIEFEVVRVPEFPDS 832
Query: 835 EMFDVDENTGVVKFIGDSLDREK-------KIMYKLSLVARDT-GGLSSEAE------LI 880
F V G V I D LDRE + Y ++ A D G S E
Sbjct: 833 SFFTVGSANGSVMAIKD-LDREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFT 891
Query: 881 IMIGDENDNKPEF 893
+ I D NDN PEF
Sbjct: 892 VSITDVNDNAPEF 904
Score = 44.0 bits (99), Expect = 0.032
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 11/160 (6%)
Query: 222 DQDLGVGATLRYELISGNDRK----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
D + G A +RY ++ +F++DS ++ + +LD E + ++ + V+
Sbjct: 597 DPNEGGNALVRYSILRNAQNSVGQAIFAIDS-ESAVITTQVGNLDRE---EIPSYDIVVK 652
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
A ++ T I + D NDN PEF + I EN+P SV +V+A D+D G
Sbjct: 653 A--VDGGAHTGTVTATIYVSDENDNPPEFPQAKSFVEISENVPVDSSVFKVIAIDRDVGI 710
Query: 338 NGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSS 376
N + K DP SG+ V+ +D E + S
Sbjct: 711 NSYSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELNES 750
Score = 43.6 bits (98), Expect = 0.043
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 16/167 (9%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
G + ++Y + R+ F++ +G + K LD + ++ Q F V AS N
Sbjct: 494 GDPSNIQYRIQQAEFREDFAIGLTSGIISSRKHLDRE-DNKGQVREFT--VTAS---NSA 547
Query: 286 KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD---QGENGEFT 342
T V I++ D+NDN P+F Y S EN G +V+ + A D D +G N
Sbjct: 548 GTTSVEVLIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVR 607
Query: 343 Y------QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
Y Q + F+ID S +T + LDRE S + V A
Sbjct: 608 YSILRNAQNSVGQAIFAIDSESAVITTQVGN-LDREEIPSYDIVVKA 653
Score = 36.7 bits (81), Expect = 4.9
Identities = 23/51 (45%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 66 DLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKA 116
D VR +G + +A ++ TV I DVNDN P FL Y + V E TP G +A
Sbjct: 873 DNVRGQSGERRNTATVTFTVSITDVNDNAPEFL-PGYTLLVPENTPAGYEA 922
>UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23;
Euteleostomi|Rep: Protocadherin alpha C2 precursor -
Homo sapiens (Human)
Length = 1007
Score = 91.5 bits (217), Expect = 2e-16
Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 33/454 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LD NDN+P F S Y ++ ++ GT++ K+ A DPD G NG + Y L ++
Sbjct: 243 ISVRVLDTNDNSPAFDQST-YRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTS 301
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
F I+ +TG V V E + ++V+A+D+ P + V ++V
Sbjct: 302 DRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDV--- 358
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P++ + Y V N T V + VND + + + + G E +PF +
Sbjct: 359 -NDNAPEV--VLTDLYS-PVPENATPNTIVAVLSVND--QDSGPNRKVSLGLEATLPFRL 412
Query: 623 E--ERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDERGVLLKG 679
S + V L R +Y+ A L+ + V + D+ND L+
Sbjct: 413 NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLED 472
Query: 680 AHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ----DVTDDIAI-AE 734
++S I+ + N G + + T+ V + + ++ VT ++I +
Sbjct: 473 SYS--IYIQENNLPGVLLCTVQATDPDE---KENAEVTYSLLEREIQGLPVTSYVSINSA 527
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT--- 791
G+++ D EK + +TV A+ +KG + +Y+ D ND+ P + T
Sbjct: 528 SGSLYAVNSFDYEKFREFFVTVEAQ-DKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTN 586
Query: 792 -YEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEGKEMFDVDENTGVVKFI 849
F M + +I A D+D G NA LF + ++F V+ +TG ++
Sbjct: 587 SSAAFEMVPRTAPAGYLVTKVI-AMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTT 645
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
D E + L++V RD G S A + I +
Sbjct: 646 RKMGD-ESGSTFNLTVVVRDNGEPSLSASVAITV 678
Score = 91.1 bits (216), Expect = 2e-16
Identities = 119/494 (24%), Positives = 195/494 (39%), Gaps = 37/494 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
VEV +LD NDN+P F P Y+ + + G A DPD+G N + Y+L + +
Sbjct: 134 VEVEILDINDNSPRF-PRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEH 192
Query: 505 LTI-TSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ P + N + + + E H L + A D R A +++ V
Sbjct: 193 FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVD---GGIPARSGTAQISVRVL- 248
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDL--LHGYEEG 617
T N P F + Y + + GT V ++ +D E ++ Y L E
Sbjct: 249 DTNDNS---PAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRER 305
Query: 618 VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVDVNDER-GV 675
F+++ +G + V+ L Y A ++ V +VDVND V
Sbjct: 306 QLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEV 365
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AIAE 734
+L +SP V EN+ I + N + N + + + + +
Sbjct: 366 VLTDLYSP----VPENATPNTIVAVLSVNDQ----DSGPNRKVSLGLEATLPFRLNGFGN 417
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
T+ PLDRE+ VY +TV A + G+ + + + I D NDNPP F +Y
Sbjct: 418 SYTLVVSGPLDRERVAVYNITVTAT-DGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSI 476
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG---- 850
+I EN+ G + ++ATD DE NA Y+L + V + G
Sbjct: 477 YIQENNLPGVLL---CTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYA 533
Query: 851 -DSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE 907
+S D EK + +++ A+D G LSS + + D ND+ P +
Sbjct: 534 VNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEM 593
Query: 908 TKLNGTAGFTIIEV 921
AG+ + +V
Sbjct: 594 VPRTAPAGYLVTKV 607
Score = 74.5 bits (175), Expect = 2e-11
Identities = 71/247 (28%), Positives = 109/247 (44%), Gaps = 21/247 (8%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+GTA ++ V N + DQ + E+ P GT ++KLNA D D G NG++RY
Sbjct: 238 SGTAQISV-RVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSL 296
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGG--NLN 1026
+S ++D ++ F I+ G V V L E S +++ + A D G +
Sbjct: 297 SS--------YTSD--RERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMA 346
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+ V V + DVND+ P T V E ++ + D D G N ++ ++
Sbjct: 347 GHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEA 406
Query: 1087 SDTDLPFEISPL--TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ LPF ++ + L V+G LDRE Y +TV A D G D+
Sbjct: 407 T---LPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGG-IPQLTSLRTLKVEISDI 462
Query: 1145 NDNSPKF 1151
NDN P F
Sbjct: 463 NDNPPSF 469
Score = 71.3 bits (167), Expect = 2e-10
Identities = 55/174 (31%), Positives = 80/174 (45%), Gaps = 8/174 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D D+G + YEL +L S LE L + QA L + A
Sbjct: 172 AQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDRE-QAALHHLVLTAV 230
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ A++ + +LD NDN P F+ Y + + E+ P G V+++ A+D D+G NG
Sbjct: 231 DGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNG 290
Query: 340 EFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
E Y L D + FSID +G VR LD E SS ++ V A + P
Sbjct: 291 ELRYSLSSYTSDRERQLFSIDASTG--EVRVIGGLDYEEASSYQIYVQATDRGP 342
Score = 68.9 bits (161), Expect = 1e-09
Identities = 107/400 (26%), Positives = 169/400 (42%), Gaps = 51/400 (12%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G + LD E+ Y++ V A ++G + AG +V + I D NDN P
Sbjct: 312 ASTGEVRVIGGLDYEEASSYQIYVQAT-DRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDL 370
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE-NTGVVKFIGD 851
+ EN+ T + ++ D D G N L E F ++ +
Sbjct: 371 YSPVPENATPNTIVA---VLSVNDQDSGPNRKVSLGL--EATLPFRLNGFGNSYTLVVSG 425
Query: 852 SLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETK 909
LDRE+ +Y +++ A D G L+S L + I D NDN P F +E++ + I +E
Sbjct: 426 PLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF--LEDSYSIYI-QENN 482
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L G T+ P K +V L + +P+ T+ + +N+ +G + Y
Sbjct: 483 LPGVLLCTVQATDPDEKENAEV-TYSLLEREIQGLPV-TSYVSINS------ASGSL-YA 533
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNI 1029
N S D + + +FV E S P S N+ +D +ND+
Sbjct: 534 VN----------SFDYEKFREFFVTVEAQD----KGSPPLSSTVTANVYVVD---MNDHA 576
Query: 1030 SVRVFVKDVNDH--FPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QP 1086
++ N F + +T A Y ++ KV A D+D GQNA L Y + Q
Sbjct: 577 PHILYPTSTNSSAAFEMVPRT------APAGY---LVTKVIAMDSDSGQNAWLFYHLAQT 627
Query: 1087 SDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
SD DL F++ TG + ++ E+ + LTVV RDNG
Sbjct: 628 SDLDL-FKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNG 666
Score = 61.7 bits (143), Expect = 2e-07
Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 15/231 (6%)
Query: 675 VLLKG-AHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+LL G A S + + V E A GA +G + + G G +R
Sbjct: 34 LLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRYLELD 93
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
G +F + +DRE R + + + V + I D NDN P F Y
Sbjct: 94 LTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFPRPNY 153
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVD-----ENTGVVK 847
+ + E+ G +++ A D D G N++ Y L E F++D EN+ V++
Sbjct: 154 QLQVSESVAPGARFHIES---AQDPDVGANSVQTYEL--SPSEHFELDLKPLQENSKVLE 208
Query: 848 FI-GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+ LDRE+ ++ L L A D G S A++ + + D NDN P F+Q
Sbjct: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQ 259
Score = 56.4 bits (130), Expect = 6e-06
Identities = 42/132 (31%), Positives = 65/132 (49%), Gaps = 8/132 (6%)
Query: 225 LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFV-LQVQASQLNN 283
LG G LR + + LD +G+LF+ + +D +A + + L+V A +N
Sbjct: 72 LGPGC-LRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLA---HN 127
Query: 284 PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
P+ A + VE+E+LD+NDN P F Y + + E++ G A D D G N TY
Sbjct: 128 PV--AVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTY 185
Query: 344 QLDDPKGAFSID 355
+L P F +D
Sbjct: 186 EL-SPSEHFELD 196
Score = 55.2 bits (127), Expect = 1e-05
Identities = 36/102 (35%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F L+ S L LD E + + + V A+ P T+ +++E+ D+NDN
Sbjct: 410 FRLNGFGNSYTLVVSGPLDRE---RVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNP 466
Query: 304 PEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
P F D Y+I I EN G + V ATD D+ EN E TY L
Sbjct: 467 PSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
Score = 54.8 bits (126), Expect = 2e-05
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1013 FRLNISALDGG--NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ + ++A DGG L +++V + D+ND+ P F + Y+ ++E +L V AT
Sbjct: 435 YNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQAT 494
Query: 1071 DADFGQNANLTY-FIQPSDTDLP----FEISPLTGVLSVNGELDRETEDKYILTVVARDN 1125
D D +NA +TY ++ LP I+ +G L D E ++ +TV A+D
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 1126 GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKAT 1185
G D+ND++P +P + S+ FE M+P
Sbjct: 555 G-SPPLSSTVTANVYVVDMNDHAPHIL---------YPTSTN-SSAAFE---MVP----- 595
Query: 1186 IEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
AP G V KV A D+D N + Y L Q
Sbjct: 596 --RTAPAGYLVTKVIAMDSD--SGQNAWLFYHLAQ 626
Score = 53.6 bits (123), Expect = 4e-05
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 10/133 (7%)
Query: 218 IHAIDQDLGVGATLRYEL---ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G LRY L S +R+LFS+D+ G + + LD + +A+++ +
Sbjct: 279 LNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE-----EASSYQI 333
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDK 333
VQA+ +V ++++D+NDN PE + D Y+ + EN V + D+
Sbjct: 334 YVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYS-PVPENATPNTIVAVLSVNDQ 392
Query: 334 DQGENGEFTYQLD 346
D G N + + L+
Sbjct: 393 DSGPNRKVSLGLE 405
Score = 51.2 bits (117), Expect = 2e-04
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
QL S ++V + D NDN P F+ + Y ++ N G ++ V+A DPD +N V Y
Sbjct: 448 QLTSLRTLKVEISDINDNPPSFLEDS-YSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
Query: 498 DL--QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALF--VEASDQPANPSERRYSLA 553
L + L +TS IN +G++ S E F VEA D+ + P +
Sbjct: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
Query: 554 VVTIEV 559
V +++
Sbjct: 567 VYVVDM 572
Score = 49.2 bits (112), Expect = 9e-04
Identities = 57/210 (27%), Positives = 84/210 (40%), Gaps = 33/210 (15%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS-- 1087
+V V + D+ND+ P F + Y V E+ A D D G N+ TY + PS
Sbjct: 133 AVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEH 192
Query: 1088 -DTDL-PFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
+ DL P + + L + LDRE + L + A D G D N
Sbjct: 193 FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGG-IPARSGTAQISVRVLDTN 251
Query: 1146 DNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
DNSP AFD+ Y+ + E++P GT V K+ A+D D
Sbjct: 252 DNSP---AFDQ-----------------------STYRVQLREDSPPGTLVVKLNASDPD 285
Query: 1206 FIGNGNGLILYSLPQRKNQQNLGLPSLSST 1235
NG + YSL + + L S+ ++
Sbjct: 286 --EGSNGELRYSLSSYTSDRERQLFSIDAS 313
Score = 48.4 bits (110), Expect = 0.002
Identities = 84/378 (22%), Positives = 147/378 (38%), Gaps = 34/378 (8%)
Query: 43 LVDSDSPQNVVKFRLGCDFDEGDDL-VRIGA---GLNQISAYLSVTVYIEDVNDNVP-IF 97
L D+ V+ G D++E + + A G ++ + V V I DVNDN P +
Sbjct: 307 LFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVV 366
Query: 98 LDTPYHVTVDELTPTGEKAFIFLI-APIGP----SLTIPLTVPRGLTIFKDIRAFDRDKP 152
L Y + TP A + + GP SL + T+P L F + P
Sbjct: 367 LTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGP 426
Query: 153 NTPNSDVHYSI-VSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLVIMASGKRIHKE 211
Y+I V+ D G L S + + + D E I +
Sbjct: 427 LDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGV 486
Query: 212 ILFPEPIHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHN 266
+L + A D D A + Y L+ + L S++S +GSL+ D +
Sbjct: 487 LLCT--VQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE---- 540
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE--FEVDFYNISIVENLPN--- 321
+ F + V+A +P ++ + ++D+ND+ P + + + E +P
Sbjct: 541 -KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAP 599
Query: 322 -GFSVLQVMATDKDQGENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLR 378
G+ V +V+A D D G+N Y L F ++ +G +R + E+ S+
Sbjct: 600 AGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTG--EIRTTRKMGDESGSTFN 657
Query: 379 MKVYAKET-NPSVVGTFA 395
+ V ++ PS+ + A
Sbjct: 658 LTVVVRDNGEPSLSASVA 675
Score = 44.0 bits (99), Expect = 0.032
Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 24/154 (15%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G+P+ S TA + V V D D + P F Y +++ E+ +V LN ++ E
Sbjct: 233 GIPARSGTAQISVRVLDTND-----NSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEG 287
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N ++RY + + R+ F ID G + ++ D E +Y++ V+A +
Sbjct: 288 SNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRG------ 341
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPK 1379
PV + G KV+V I DVNDN+P+
Sbjct: 342 ----PVP---MAG----HCKVLVDIVDVNDNAPE 364
>UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23;
Euteleostomi|Rep: Protocadherin-17 precursor - Homo
sapiens (Human)
Length = 1159
Score = 91.5 bits (217), Expect = 2e-16
Identities = 119/471 (25%), Positives = 205/471 (43%), Gaps = 48/471 (10%)
Query: 443 VNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQR 501
V + V ++D+NDN+PVF PS L E + NA +GTV+ + A D D G NG VLY
Sbjct: 227 VQINVKVIDSNDNSPVFEAPSYLVE--LPENAPLGTVVIDLNATDADEGPNGEVLYSFSS 284
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ F I+P TG + V + E G + V+A D NP + V I+
Sbjct: 285 YVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLID- 343
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEG 617
N P I F+ + + GT + +RV D+ + + +L G G
Sbjct: 344 ---RNDNAPSI-GFVSV-RQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTG 398
Query: 618 -----------VPFAVEER-SGVITVVDD--LSRYNRPMYDFEAVALQENA-NLSIVTNA 662
VPF +EE TVV D L R + Y+ VA + L+ +
Sbjct: 399 GGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSF 458
Query: 663 TVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIA 721
+ ++D ND KG + + V EN+ G +G + + + NGT + L +
Sbjct: 459 AIKILDENDNPPRFTKGLY---VLQVHENNIPGEYLGSVLAQD-PDLGQNGTVSYSILPS 514
Query: 722 NQQDVTDDIAIA---EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ DV+ ++ +G I+ + + E+ + V+A+ + V + +
Sbjct: 515 HIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVL 574
Query: 779 DENDNPPV-----FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GE 832
D NDN PV ++ T E + N+ +G + + ++A D+D G + Y + G
Sbjct: 575 DVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLV---STVRALDSDFGESGRLTYEIVDGN 631
Query: 833 GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELII 881
+F++D ++G ++ + + ++ +L + D G LS+ A+LII
Sbjct: 632 DDHLFEIDPSSGEIRTLHPFWEDVTPVV-ELVVKVTDHGKPTLSAVAKLII 681
Score = 89.4 bits (212), Expect = 7e-16
Identities = 123/483 (25%), Positives = 193/483 (39%), Gaps = 55/483 (11%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
++V + D NDN P F S+ E + NA GT A DPD G+NG+ Y L R +
Sbjct: 118 IKVEIQDINDNAPSF-SSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH 176
Query: 505 LTITSPFKINPNTGT------VSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
K + GT + A + H L + A D P + V I+
Sbjct: 177 GLFGLDVK-SRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVID 235
Query: 559 VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV 618
+ + P F Y + N +GT V + DA E + ++L+ + V
Sbjct: 236 -------SNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADE--GPNGEVLYSFSSYV 286
Query: 619 P------FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVND 671
P F+++ ++G+I V +L M + + A N + TV ++D ND
Sbjct: 287 PDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRND 346
Query: 672 E----------RGVLLKGAHSPIIF---HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+G L + A + V + +G GQ+ + G GTG
Sbjct: 347 NAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKN-GQL---QCRVLGGGGTGGGGG 402
Query: 719 LIANQQDVTDDIAIAEDG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
L V + D T+ T +PLDRE +D Y +T++A + G I
Sbjct: 403 LGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVAR-DGGSPPLNSTKSFAIK 461
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGE 832
I DENDNPP F Y + EN+ G + + A D D G N Y++ G+
Sbjct: 462 ILDENDNPPRFTKGLYVLQVHENNIPGEYL---GSVLAQDPDLGQNGTVSYSILPSHIGD 518
Query: 833 GKEMFDVDEN-TGVVKFIGDSLDREKKIMYKLSLVARDTGG---LSSEAELIIMIGDEND 888
V N T + S + E+ ++ ++A+D+G L S A + + + D ND
Sbjct: 519 VSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVND 578
Query: 889 NKP 891
N P
Sbjct: 579 NAP 581
Score = 85.0 bits (201), Expect = 1e-14
Identities = 77/284 (27%), Positives = 135/284 (47%), Gaps = 25/284 (8%)
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNATVHVVDVNDERGVLLKGA 680
V+ SG++ + R + ++ + ++L+ AN + V + D+ND +
Sbjct: 77 VDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPSF---S 133
Query: 681 HSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD---VTDDIAIAEDGT 737
I + EN AA G F + G +R + + D D+ DGT
Sbjct: 134 SDQIEMDISEN---AAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGT 190
Query: 738 IFT----QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
F QK LDRE+++ + + V+ + G + Q+ + + D NDN PVFE +Y
Sbjct: 191 KFPELVIQKALDREQQNHHTL-VLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVKFI 849
+ EN+ +GT + +D + ATDADEG N +Y+ +E+F +D TG+++
Sbjct: 250 VELPENAPLGT-VVID--LNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVK 306
Query: 850 GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
G +LD E+ M ++ + ARD G + + ++ + + D NDN P
Sbjct: 307 G-NLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAP 349
Score = 85.0 bits (201), Expect = 1e-14
Identities = 58/180 (32%), Positives = 90/180 (50%), Gaps = 12/180 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTFVLQV 276
A D D G LR L++ +D LF LD + G+ F E + + Q N L +
Sbjct: 156 AHDPDAGENG-LRTYLLTRDDHGLFGLDVKSRGDGTKFPELVIQKALDRE-QQNHHTLVL 213
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P ++A ++ ++++D NDN P FE Y + + EN P G V+ + ATD D+G
Sbjct: 214 TALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEG 273
Query: 337 ENGEFTYQL-----DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
NGE Y D + FSIDP++G + V+ LD E + L + V A++ P+ +
Sbjct: 274 PNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGN--LDYEENGMLEIDVQARDLGPNPI 331
Score = 78.6 bits (185), Expect = 1e-12
Identities = 108/433 (24%), Positives = 179/433 (41%), Gaps = 58/433 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN P+GT +I LNA D D G NG++ Y F+S Y+P V+ F I+ + G
Sbjct: 252 LPENAPLGTVVIDLNATDADEGPNGEVLYSFSS--YVPD--------RVRELFSIDPKTG 301
Query: 1000 HVIVARSLPPESE--FRLNISALD-GGN-LNDNISVRVFVKDVNDHFP-VFKKTWYNFNV 1054
+ V +L E +++ A D G N + + V V + D ND+ P + + +
Sbjct: 302 LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGAL 361
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPS------------DTDLPFEISPLTG-- 1100
EA V+ V TD D G+N L + +PF++
Sbjct: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNF 421
Query: 1101 -VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
+ + LDRET+D+Y +T+VARD G D NDN P+F +L+
Sbjct: 422 YTVVTDRPLDRETQDEYNVTIVARDGG-SPPLNSTKSFAIKILDENDNPPRFTKGLYVLQ 480
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-----IGNGNGLI 1214
+ + SV+ + +N + ++ D + NG I
Sbjct: 481 ---VHENNIPGEYLGSVL---AQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAI 534
Query: 1215 L----YSLPQRKN------QQNLGLPS-LSSTAILMVTVADVPDEVEMSDKPVFISRYYE 1263
++ Q K ++ G P+ L S A + VTV DV D + P + E
Sbjct: 535 YALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAE 594
Query: 1264 LEIEENVNAP--VELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSP 1321
L++ N V V ++ E+ ++ Y I++ ND + F IDP +G + +
Sbjct: 595 LQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHL---FEIDPSSGEIRTLHPF 651
Query: 1322 DREVKDTYEVIVR 1334
+V E++V+
Sbjct: 652 WEDVTPVVELVVK 664
Score = 68.9 bits (161), Expect = 1e-09
Identities = 56/197 (28%), Positives = 85/197 (43%), Gaps = 9/197 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S + + +LD NDN P F LY + N G +G V A DPDLGQNG V Y
Sbjct: 452 LNSTKSFAIKILDENDNPPRFT-KGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYS 510
Query: 499 L--QRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVT 556
+ +++I + +NP G + S E A + + + S A V
Sbjct: 511 ILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVR 570
Query: 557 IEVTRGTKGNKPDI--PDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLH 612
+ V N P I P E V N G+G V +R +D E ++Y+++
Sbjct: 571 VTVL-DVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVD 629
Query: 613 GYEEGVPFAVEERSGVI 629
G ++ + F ++ SG I
Sbjct: 630 GNDDHL-FEIDPSSGEI 645
Score = 64.1 bits (149), Expect = 3e-08
Identities = 66/227 (29%), Positives = 93/227 (40%), Gaps = 19/227 (8%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
LN T F I + + L L + NIP G + + A D D G NG + Y
Sbjct: 452 LNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP-GEYLGSVLAQDPDLGQNGTVSYS 510
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGG---N 1024
I PS + + + Y +N +G + RS E F + A D G +
Sbjct: 511 ------ILPSHIGD--VSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAH 562
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRR-----VLGKVDATDADFGQNAN 1079
L N +VRV V DVND+ PV + E Q R ++ V A D+DFG++
Sbjct: 563 LESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGR 622
Query: 1080 LTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
LTY I + D FEI P +G + + L V D+G
Sbjct: 623 LTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHG 669
Score = 63.3 bits (147), Expect = 5e-08
Identities = 64/217 (29%), Positives = 93/217 (42%), Gaps = 15/217 (6%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I EN GT +A D D+G NG Y + + L+VK +
Sbjct: 141 ISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH------GLFGLDVKSRGD-GTKFP 193
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVK--DVNDHFPVFKKTWYNFNVE 1055
+++ ++L E + L ++ALDGG + +V++ VK D ND+ PVF+ Y +
Sbjct: 194 ELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELP 253
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRET 1112
E V+ ++ATDAD G N + Y P F I P TG++ V G LD E
Sbjct: 254 ENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEE 313
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ V ARD G D NDN+P
Sbjct: 314 NGMLEIDVQARDLG-PNPIPAHCKVTVKLIDRNDNAP 349
Score = 60.9 bits (141), Expect = 3e-07
Identities = 66/251 (26%), Positives = 105/251 (41%), Gaps = 28/251 (11%)
Query: 125 GPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLL 184
GP ++P + F + DR + + +IV+ D G L S+ +
Sbjct: 405 GPGGSVPFKLEENYDNFYTV-VTDRPLDRETQDEYNVTIVA-RDGGSPPLNSTKSFAI-- 460
Query: 185 RKVLDYDAGDKEFQ---LVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGN-- 239
K+LD + F V+ I E L + A D DLG T+ Y ++ +
Sbjct: 461 -KILDENDNPPRFTKGLYVLQVHENNIPGEYL--GSVLAQDPDLGQNGTVSYSILPSHIG 517
Query: 240 DRKLFSLDSVN---GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT-AQARVEIE 295
D +++ SVN G+++ + + + Q F +V A P + A V +
Sbjct: 518 DVSIYTYVSVNPTNGAIYALRSFNFE-----QTKAFEFKVLAKDSGAPAHLESNATVRVT 572
Query: 296 LLDLNDN-----LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
+LD+NDN LP + D + + N G+ V V A D D GE+G TY++ D
Sbjct: 573 VLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGND 632
Query: 351 --AFSIDPRSG 359
F IDP SG
Sbjct: 633 DHLFEIDPSSG 643
Score = 60.5 bits (140), Expect = 3e-07
Identities = 52/170 (30%), Positives = 79/170 (46%), Gaps = 14/170 (8%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNPPVFEHAT 791
A+ G ++T++ +DRE + R + + V + I + + I+D NDN P F
Sbjct: 79 ADSGLLYTKQRIDRES--LCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPSFSSDQ 136
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF--DVDENTGVVKF- 848
E I EN+ GT + + A D D G N L Y L + +F DV KF
Sbjct: 137 IEMDISENAAPGTRFPLTS---AHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFP 193
Query: 849 ---IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
I +LDRE++ + L L A D G S+ ++ + + D NDN P F
Sbjct: 194 ELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVF 243
Score = 55.6 bits (128), Expect = 1e-05
Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 10/129 (7%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDA--EHNLQANTFVLQVQASQLNNPLKTAQA 290
Y ++ + L +D+ +G L+ ++ +D ++ HN + Q+ N +
Sbjct: 64 YRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKC-----QLSLEVFANDKEICMI 118
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPK 349
+VEI+ D+NDN P F D + I EN G A D D GENG TY L D
Sbjct: 119 KVEIQ--DINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH 176
Query: 350 GAFSIDPRS 358
G F +D +S
Sbjct: 177 GLFGLDVKS 185
Score = 52.8 bits (121), Expect = 7e-05
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 218 IHAIDQDLGVGATLRYELIS---GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
++A D D G + Y S R+LFS+D G + ++ LD + L+ +
Sbjct: 265 LNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLE-----I 319
Query: 275 QVQASQLN-NPLKTAQARVEIELLDLNDNLPEFE-VDFYNISIVENLPNGFSVLQVMATD 332
VQA L NP+ A +V ++L+D NDN P V ++ E P G + V TD
Sbjct: 320 DVQARDLGPNPIP-AHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTD 378
Query: 333 KDQGENGE 340
+D G+NG+
Sbjct: 379 RDSGKNGQ 386
Score = 50.0 bits (114), Expect = 5e-04
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 21/142 (14%)
Query: 772 QVTIYIEDENDNPPVFEHATY-EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF 830
+VT+ + D NDN P + +G + E + GT I + ++ TD D G N +
Sbjct: 336 KVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIAL---VRVTDRDSGKNGQLQCRVL 392
Query: 831 GEG-------------KEMFDVDEN-TGVVKFIGDS-LDREKKIMYKLSLVARDTGG--L 873
G G F ++EN + D LDRE + Y +++VARD G L
Sbjct: 393 GGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPL 452
Query: 874 SSEAELIIMIGDENDNKPEFNQ 895
+S I I DENDN P F +
Sbjct: 453 NSTKSFAIKILDENDNPPRFTK 474
Score = 43.2 bits (97), Expect = 0.056
Identities = 52/193 (26%), Positives = 74/193 (38%), Gaps = 35/193 (18%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
++V ++D+ND+ P F ++ E A D D G+N TY + D
Sbjct: 118 IKVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHG 177
Query: 1091 L-PFEI-SPLTGV----LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
L ++ S G L + LDRE ++ + L + A D G D
Sbjct: 178 LFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGG-EPPRSATVQINVKVIDS 236
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
NDNSP F A L+E + ENAP+GT V + A D
Sbjct: 237 NDNSPVFEAPSYLVE--------------------------LPENAPLGTVVIDLNATDA 270
Query: 1205 DFIGNGNGLILYS 1217
D NG +LYS
Sbjct: 271 D--EGPNGEVLYS 281
Score = 39.9 bits (89), Expect = 0.53
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 7/110 (6%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P S+T + V V D D + PVF + Y +E+ EN ++ LN T+ E
Sbjct: 219 GEPPRSATVQINVKVIDSND-----NSPVFEAPSYLVELPENAPLGTVVIDLNATDADEG 273
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRA 1335
N ++ Y + +R F IDP+ G + + + D E E+ V+A
Sbjct: 274 PNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQA 323
Score = 39.9 bits (89), Expect = 0.53
Identities = 52/186 (27%), Positives = 79/186 (42%), Gaps = 30/186 (16%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P L+ST + + D E + P F Y L++ EN N P E + L + +
Sbjct: 448 GSPPLNSTKSFAIKILD-----ENDNPPRFTKGLYVLQVHEN-NIPGEYLGSVLAQDPDL 501
Query: 1287 --NFKMRYYILNENDTDIR-RTFV-IDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSR 1342
N + Y IL + D+ T+V ++P NG +Y +RS + E +E V A K S
Sbjct: 502 GQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLA---KDSG 558
Query: 1343 ELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKF---TNGNRPLVTAIPTTAPFGY 1399
H+ + + V V + DVNDN+P T N +P A GY
Sbjct: 559 APAHL-------------ESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGY 605
Query: 1400 QVMQLK 1405
V ++
Sbjct: 606 LVSTVR 611
Score = 37.5 bits (83), Expect = 2.8
Identities = 14/36 (38%), Positives = 21/36 (58%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSL 253
+ A+D D G L YE++ GND LF +D +G +
Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEI 645
>UniRef50_P55291 Cluster: Cadherin-15 precursor; n=11;
Tetrapoda|Rep: Cadherin-15 precursor - Homo sapiens
(Human)
Length = 814
Score = 91.5 bits (217), Expect = 2e-16
Identities = 72/217 (33%), Positives = 107/217 (49%), Gaps = 24/217 (11%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G +F LDREK D +R+ A + G + + I + D+NDN P F + G
Sbjct: 102 GKVFLNAMLDREKTDRFRLRAFA-LDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFTGR 160
Query: 796 IMENSKIGTEIKMDNIIKATDAD--EGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDS 852
++E + GT + +ATDAD E NA +++ +G E+F +DE TG ++ +
Sbjct: 161 VLEGAVPGTYVTR---AEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRTVQVG 217
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ-------IEENSKVR 903
LDRE +Y L+L D GL++ A II + D NDN PEF + IE S V
Sbjct: 218 LDREVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVSGVD 277
Query: 904 IHR----ETKLNGT----AGFTIIEVKPKNKFALDVD 932
+ R + L G+ A FTI+E P +F + D
Sbjct: 278 VGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTD 314
Score = 61.3 bits (142), Expect = 2e-07
Identities = 53/172 (30%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 987 EVKRYFVINERHGHVIVARSLPPES--EFRLNISALD--GGNLNDNISVRVFVKDVNDHF 1042
E + F I++ G V + L E FRL ALD G L D + + V D ND+
Sbjct: 90 EPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNR 149
Query: 1043 PVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ--NANLTYFIQPSDTDLPFEISPLTG 1100
P F + + V E + + +ATDAD + NA L + I + F I LTG
Sbjct: 150 PAFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTG 209
Query: 1101 -VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ +V LDRE Y LT+ D D+NDN+P+F
Sbjct: 210 EIRTVQVGLDREVVAVYNLTLQVADM-SGDGLTATASAIITLDDINDNAPEF 260
Score = 59.7 bits (138), Expect = 6e-07
Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 11/191 (5%)
Query: 229 ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA 288
A LR+ ++ +LFS+D + G + ++ LD E + L +Q + ++ TA
Sbjct: 187 AALRFSILQQGSPELFSIDELTGEI-RTVQVGLDRE---VVAVYNLTLQVADMSGDGLTA 242
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN----GEFTYQ 344
A I L D+NDN PEF D + + +E + +G V ++ D+D + FT
Sbjct: 243 TASAIITLDDINDNAPEFTRDEFFMEAIEAV-SGVDVGRLEVEDRDLPGSPNWVARFTIL 301
Query: 345 LDDPKGAFSI--DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAK 402
DP G F+I DP++ + LD E+ +KV + P + AK
Sbjct: 302 EGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQAK 361
Query: 403 WRRQPLETNAP 413
R +TN P
Sbjct: 362 VRVHVQDTNEP 372
Score = 54.4 bits (125), Expect = 2e-05
Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 12/170 (7%)
Query: 209 HKEILFP-EPIHAIDQDLG-VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
HK + +P I + Q LG V +++ + R +FS+D G +FL LD +
Sbjct: 58 HKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDR 117
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
+ F L + S L +P +EI ++D NDN P F + + ++E G V
Sbjct: 118 FRLRAFALDLGGSTLEDPTD-----LEIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVT 172
Query: 327 QVMATDKDQGENG----EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ ATD D E F+ FSID +G + Q LDRE
Sbjct: 173 RAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRT-VQVGLDRE 221
Score = 37.5 bits (83), Expect = 2.8
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 148 DRDKPNTPNSDVHYSIVSGNDDGHFALESSHKP---VLLLRKVLDYDA 192
DRD P +PN ++I+ G+ DG F + + K VL + K LDY++
Sbjct: 285 DRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYES 332
>UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
SCAF14742, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1105
Score = 91.1 bits (216), Expect = 2e-16
Identities = 115/421 (27%), Positives = 176/421 (41%), Gaps = 64/421 (15%)
Query: 742 KPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
K LDRE ++ + ++A ++KG +G + + I D NDN P FE ++ + E++
Sbjct: 141 KELDREVQESVELILVA-WDKGDPPRSGSTSIHVRILDSNDNSPTFEDSSPTLELPEDTA 199
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEMFDVDENTGVVKFIGDSLDREK 857
GT + +KATD D+G N Y+L E + + VD T V + LD E
Sbjct: 200 RGTTVIR---LKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVS-LKAPLDYEV 255
Query: 858 KIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAG 915
+ Y++ + ARD G + + +L I + D NDN P I + G+ G
Sbjct: 256 QSSYEVVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRP-----------GSPG 304
Query: 916 FTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
T++E P++ F L L+ LD DSG NGQ++ E
Sbjct: 305 PTVLEGAPRDTF---------LSLV-------------MVLDADSGRNGQVKAEI----- 337
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL--DGGN--LNDNISV 1031
D R + + ++ +L E NI+ L D G+ L+ +
Sbjct: 338 -------LDGSGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQL 390
Query: 1032 RVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ---PSD 1088
V V D ND+ PVF + Y + EE T + KV A D D + ++YFI+ +
Sbjct: 391 TVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLELSGRVSYFIRNATRAQ 450
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
F + P +G++ LD ET Y V A D G DVNDN
Sbjct: 451 AATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQG-HPPLSSTATVQIEIRDVNDNY 509
Query: 1149 P 1149
P
Sbjct: 510 P 510
Score = 80.6 bits (190), Expect = 3e-13
Identities = 115/434 (26%), Positives = 178/434 (41%), Gaps = 48/434 (11%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V +LD+NDN+P F S+ + + GT + ++KA DPD G NG V Y L R +
Sbjct: 170 SIHVRILDSNDNSPTFEDSSP-TLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSRHT 228
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
+ ++P T VS+ ++P+ ++ + + VEA D+ N L + ++V
Sbjct: 229 RPEVQRLLAVDPQTAAVSL-KAPLDYEVQSSYEVVVEARDRGPNAVPAYCKLHIKLLDVN 287
Query: 561 RGTKGNKPDIP---DFMGAPYEFWV-GSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
N P I D G+P + G+ S+ + D+ V ++L G
Sbjct: 288 ----DNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQVKAEILDG--- 340
Query: 617 GVPFAVEE-RSGVITVVDD--LSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDE 672
PF ++ + G T+V + L R Y+ +A + LS + TVHV+D ND
Sbjct: 341 SGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDN 400
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ---QDVTDD 729
V + + NS G Q+ + +G V + I N Q T
Sbjct: 401 APVFSTSLYKASF--EETNSTGY---QVLKVQARDVDLELSGRVSYFIRNATRAQAATYF 455
Query: 730 IAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-E 788
G + +PLD E Y V A ++G + V I I D NDN PV E
Sbjct: 456 SVHPTSGLVRALRPLDYETSRSYWFLVEA-VDQGHPPLSSTATVQIEIRDVNDNYPVVKE 514
Query: 789 HATYEGFIM-------ENSKIGTEIKMD----------NIIKATDADEGTNALFMYTLF- 830
A G + +I TE+ M + I+A DAD G N Y L
Sbjct: 515 PAPRRGVASLSIPVNADKGEIVTELGMSTREGRAAFLVSTIQAEDADSGLNGQLTYQLTR 574
Query: 831 GEGKEMFDVDENTG 844
E +F +D TG
Sbjct: 575 AEPNPLFWLDAATG 588
Score = 70.9 bits (166), Expect = 2e-10
Identities = 88/318 (27%), Positives = 142/318 (44%), Gaps = 42/318 (13%)
Query: 734 EDG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
+DG TI T LDREK Y +T++A + G + + Q+T+++ DENDN PVF +
Sbjct: 350 QDGSYTIVTNGTLDREKVTHYNITLLAR-DHGDPPLSTLGQLTVHVLDENDNAPVFSTSL 408
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL----FGEGKEMFDVDENTGVVK 847
Y+ E + G ++ ++A D D + Y + + F V +G+V+
Sbjct: 409 YKASFEETNSTGYQVLK---VQARDVDLELSGRVSYFIRNATRAQAATYFSVHPTSGLVR 465
Query: 848 FIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+ LD E Y + A D G LSS A + I I D NDN P ++E + R
Sbjct: 466 AL-RPLDYETSRSYWFLVEAVDQGHPPLSSTATVQIEIRDVNDNYP---VVKEPAPRR-- 519
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
G A +I K + V +LG + + + A D DSGLNGQ
Sbjct: 520 ------GVASLSIPVNADKGEI---VTELG---MSTREGRAAFLVSTIQAEDADSGLNGQ 567
Query: 966 IRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG-- 1023
+ Y+ P L A ++ +N + ++ ++ FRL+IS DGG
Sbjct: 568 LTYQLTRAEPNPLFWLDAATGQL----FVNTTNATQLIGQT------FRLDISVSDGGRP 617
Query: 1024 NLNDNISVRVFVKDVNDH 1041
+L+ +++ V ++ DH
Sbjct: 618 SLSTGLTLEVTFINLRDH 635
Score = 67.3 bits (157), Expect = 3e-09
Identities = 42/152 (27%), Positives = 77/152 (50%), Gaps = 12/152 (7%)
Query: 248 SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFE 307
S L + KELD + + +++ L + A +P ++ + + +LD NDN P FE
Sbjct: 132 SKQAELVIIKELDREVQESVE-----LILVAWDKGDPPRSGSTSIHVRILDSNDNSPTFE 186
Query: 308 VDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-----DPKGAFSIDPRSGWLT 362
+ + E+ G +V+++ ATD DQG NGE Y L + + ++DP++ ++
Sbjct: 187 DSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVS 246
Query: 363 VRNQTVLDREAHSSLRMKVYAKETNPSVVGTF 394
++ LD E SS + V A++ P+ V +
Sbjct: 247 LK--APLDYEVQSSYEVVVEARDRGPNAVPAY 276
Score = 62.5 bits (145), Expect = 9e-08
Identities = 70/252 (27%), Positives = 105/252 (41%), Gaps = 27/252 (10%)
Query: 914 AGFTIIEVK--PKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN 971
+G T I V+ N + + P +PE+ GTT+I+L A D D GLNG++ Y +
Sbjct: 166 SGSTSIHVRILDSNDNSPTFEDSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLS 225
Query: 972 SEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNI 1029
+ P EV+R ++ + V + L E S + + + A D G
Sbjct: 226 R--HTRP--------EVQRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEARDRGPNAVPA 275
Query: 1030 SVRVFVK--DVNDHFPVFKKTW-----YNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
++ +K DVND+ P W V E L V DAD G+N +
Sbjct: 276 YCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQVKA 335
Query: 1083 FIQPSDTDLPFEISPL---TGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
I D PF + + + + NG LDRE Y +T++ARD+G
Sbjct: 336 EI--LDGSGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHG-DPPLSTLGQLTV 392
Query: 1140 XXXDVNDNSPKF 1151
D NDN+P F
Sbjct: 393 HVLDENDNAPVF 404
Score = 55.2 bits (127), Expect = 1e-05
Identities = 67/303 (22%), Positives = 128/303 (42%), Gaps = 18/303 (5%)
Query: 603 QNDVSYDLLHGYEEGVPFAVE-ERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVT 660
+ D+ + G +PF + + ++ +L R + + VA + + S T
Sbjct: 110 EQDLEISEMAGLRMRIPFGASGSKQAELVIIKELDREVQESVELILVAWDKGDPPRSGST 169
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
+ V ++D ND SP + ++ + G + ++ T+ NG
Sbjct: 170 SIHVRILDSNDNSPTFEDS--SPTLELPEDTARGTTVIRLKATDPDQGL-NGEVAYSLSR 226
Query: 721 ANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIED 779
+ +V +A+ + + + PLD E + Y + V A ++G + ++ I + D
Sbjct: 227 HTRPEVQRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEAR-DRGPNAVPAYCKLHIKLLD 285
Query: 780 ENDNPP----VFEHATYEG-FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEG 833
NDN P +++ G ++E + T + +++ DAD G N + G G
Sbjct: 286 VNDNAPRILFIWDRPGSPGPTVLEGAPRDTFL---SLVMVLDADSGRNGQVKAEILDGSG 342
Query: 834 KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
++ +LDREK Y ++L+ARD G LS+ +L + + DENDN P
Sbjct: 343 PFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDNAP 402
Query: 892 EFN 894
F+
Sbjct: 403 VFS 405
Score = 55.2 bits (127), Expect = 1e-05
Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 9/165 (5%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN 492
++ D L + + V +LD NDN PVF ++LY+ S + G + KV+A D DL +
Sbjct: 378 DHGDPPLSTLGQLTVHVLDENDNAPVF-STSLYKASFEETNSTGYQVLKVQARDVDLELS 436
Query: 493 GMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA--LFVEASDQPANPSERRY 550
G V Y ++ + + F ++P +G V E + VEA DQ P
Sbjct: 437 GRVSYFIRNATRAQAATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHPPLS--- 493
Query: 551 SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
S A V IE+ R N P + + AP ++ + G+I
Sbjct: 494 STATVQIEI-RDVNDNYPVVKE--PAPRRGVASLSIPVNADKGEI 535
Score = 52.4 bits (120), Expect = 9e-05
Identities = 48/165 (29%), Positives = 71/165 (43%), Gaps = 13/165 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSV-NGSLFLEKELDLDAEHNLQANTFVLQV 276
+ +D D G ++ E++ G+ F L V +GS + LD E N +L
Sbjct: 320 VMVLDADSGRNGQVKAEILDGSGP--FRLKHVQDGSYTIVTNGTLDREKVTHYNITLL-- 375
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A +P + ++ + +LD NDN P F Y S E G+ VL+V A D D
Sbjct: 376 -ARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLE 434
Query: 337 ENGEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDREAHSS 376
+G +Y + + A FS+ P SG VR LD E S
Sbjct: 435 LSGRVSYFIRNATRAQAATYFSVHPTSG--LVRALRPLDYETSRS 477
Score = 49.2 bits (112), Expect = 9e-04
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGND---RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G+ + Y L ++L ++D ++ L+ LD + + +++ +
Sbjct: 207 LKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVSLKAPLDYEVQ-----SSYEV 261
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSVLQVM 329
V+A A ++ I+LLD+NDN P +++E P + VM
Sbjct: 262 VVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVM 321
Query: 330 ATDKDQGENGEFTYQLDDPKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D G NG+ ++ D G F + + G T+ LDRE + + + A++
Sbjct: 322 VLDADSGRNGQVKAEILDGSGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARD 378
Score = 42.7 bits (96), Expect = 0.075
Identities = 47/184 (25%), Positives = 80/184 (43%), Gaps = 35/184 (19%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARS 1006
G ++K+ A D+D L+G++ Y + A + YF ++ G V R
Sbjct: 420 GYQVLKVQARDVDLELSGRVSYFIRN----------ATRAQAATYFSVHPTSGLVRALRP 469
Query: 1007 LPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNV-------- 1054
L E+ + + A+D G+ L+ +V++ ++DVND++PV K+ V
Sbjct: 470 LDYETSRSYWFLVEAVDQGHPPLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVN 529
Query: 1055 --------EEAQYTRR-----VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGV 1101
E TR ++ + A DAD G N LTY + ++ + F + TG
Sbjct: 530 ADKGEIVTELGMSTREGRAAFLVSTIQAEDADSGLNGQLTYQLTRAEPNPLFWLDAATGQ 589
Query: 1102 LSVN 1105
L VN
Sbjct: 590 LFVN 593
Score = 42.3 bits (95), Expect = 0.099
Identities = 63/253 (24%), Positives = 106/253 (41%), Gaps = 39/253 (15%)
Query: 1091 LPFEISPLTGVLSVNGELDRET----ED--KYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
LPF +S GVLS G LDRE D + +L+V+ R +G D
Sbjct: 44 LPFSVSARDGVLSTQGRLDREELCRGSDLCEVLLSVLYRRSGAMTCLRVRVEVM----DQ 99
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDT 1204
ND+SP+F ++ LE E++ M IP + A+ + A + + K +
Sbjct: 100 NDHSPRFPRAEQDLE-----ISEMAGLR----MRIP-FGASGSKQAEL--VIIKELDRE- 146
Query: 1205 DFIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
+ LIL + + G P S + + V + D D + P F L
Sbjct: 147 --VQESVELILVAWDK-------GDPPRSGSTSIHVRILDSND-----NSPTFEDSSPTL 192
Query: 1265 EIEENVNAPVELVSLNLTEHYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
E+ E+ ++ L T+ + N ++ Y + +++R +DP+ + L D
Sbjct: 193 ELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVSLKAPLD 252
Query: 1323 REVKDTYEVIVRA 1335
EV+ +YEV+V A
Sbjct: 253 YEVQSSYEVVVEA 265
Score = 38.7 bits (86), Expect = 1.2
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
I A D D G+ L Y+L LF LD+ G LF ++ L TF L +
Sbjct: 555 IQAEDADSGLNGQLTYQLTRAEPNPLFWLDAATGQLF----VNTTNATQLIGQTFRLDIS 610
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNL 303
S P + +E+ ++L D+L
Sbjct: 611 VSDGGRPSLSTGLTLEVTFINLRDHL 636
>UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadherin
beta 15 precursor (PCDH-beta15); n=6; Gallus gallus|Rep:
PREDICTED: similar to Protocadherin beta 15 precursor
(PCDH-beta15) - Gallus gallus
Length = 927
Score = 90.2 bits (214), Expect = 4e-16
Identities = 80/281 (28%), Positives = 129/281 (45%), Gaps = 17/281 (6%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN---ANLSIVTNATVHVVDVNDERGVL 676
F ++ SGV+TV + L R R E+ AL N + V V DVND V
Sbjct: 433 FRLDPHSGVLTVTETLDR-ERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVF 491
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD--IAIAE 734
++ V E ++ + + + NG N + + AE
Sbjct: 492 ---PQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLSPNPYFSLALEKWKGGAE 548
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+ QKPLDRE++ + V+ + G +G QV + + D NDN PVF YE
Sbjct: 549 FVKLVLQKPLDREEQRELHL-VLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEV 607
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYT---LFGEGKEMFDVDENTGVVKFIGD 851
+ ENS G + + A D DEG+N YT + + +++++++ TG ++ G
Sbjct: 608 RVAENSPPGQLVVR---VSAADPDEGSNGKVRYTFTEMSEQSQQLYELNPETGEIRVSG- 663
Query: 852 SLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPE 892
+LD E++ M++L + A D GGLS+ + + + D NDN PE
Sbjct: 664 NLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPE 704
Score = 85.4 bits (202), Expect = 1e-14
Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 20/217 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G +++++A D D G NG++RY F +++S + ++ + +N G
Sbjct: 609 VAENSPPGQLVVRVSAADPDEGSNGKVRYTF--------TEMSEQSQQL---YELNPETG 657
Query: 1000 HVIVARSLPPESE--FRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ V+ +L E E L + A+DGG L+ + V V V DVND+ P + + ++ E
Sbjct: 658 EIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPEIALSSVSASIPED 717
Query: 1058 QYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETED 1114
R V+ + D D G N I + D+PF ++ L + LDRET
Sbjct: 718 APPRTVVALLSVRDRDSGDNGRTECAI---EGDVPFSLTAAFANHYELRTSAALDRETTA 774
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y +++VA D G DVNDN+P+F
Sbjct: 775 EYNVSIVATDWG-RARLSARESVSVRIADVNDNAPRF 810
Score = 78.6 bits (185), Expect = 1e-12
Identities = 104/413 (25%), Positives = 161/413 (38%), Gaps = 31/413 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + + EV + D ND++PVF P + A G+ A D D+G NG+
Sbjct: 469 ENPVQLIRGEVEVRDVNDHSPVF-PQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQN 527
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI--LEGRHA-LFVEASDQPANPSERRYSLA 553
Y L ++ V + P+ E R L + A+D + P +
Sbjct: 528 YSLSPNPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVR 587
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
VV ++ ++P F YE V N G V ++ D E ++ V Y
Sbjct: 588 VVVLDAN-------DNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFT 640
Query: 612 HGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVN 670
E+ + + +G I V +L M++ V + LS V V+DVN
Sbjct: 641 EMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHEL-VVRAMDGGGLSAHCRVHVEVLDVN 699
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
D + A S + + E++ + + NG R A + DV +
Sbjct: 700 DNAPEI---ALSSVSASIPEDAPPRTVVALLSVRDRDSGDNG----RTECAIEGDVPFSL 752
Query: 731 --AIAEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVF 787
A A + T LDRE Y ++++A ++ + +S V++ I D NDN P F
Sbjct: 753 TAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARE--SVSVRIADVNDNAPRF 810
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV 839
A Y + EN I +KATDAD G N Y L EG+E DV
Sbjct: 811 TQAAYSMSVSENEAGAVRI---GSVKATDADAGANGRVRYALVREEGEERPDV 860
Score = 76.2 bits (179), Expect = 7e-12
Identities = 68/238 (28%), Positives = 106/238 (44%), Gaps = 18/238 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV+ N + Q + + E G+ +A D D G+NG Y + Y
Sbjct: 479 VEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLSPNPYF-- 536
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVF 1034
L+ + + FV +++ + L E E L ++A DGG+ + VRV
Sbjct: 537 -SLALEKWKGGAEFV------KLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVV 589
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSD-TDLP 1092
V D ND+ PVF + Y V E +++ +V A D D G N + Y F + S+ +
Sbjct: 590 VLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQL 649
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
+E++P TG + V+G LD E E + L V A D G DVNDN+P+
Sbjct: 650 YELNPETGEIRVSGNLDYEEEKMHELVVRAMDGG---GLSAHCRVHVEVLDVNDNAPE 704
Score = 70.5 bits (165), Expect = 3e-10
Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 15/162 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS-----LFLEKELDLDAEHNLQANTFVL 274
A D+D+G+ Y L S N +L+ G L L+K LD + + L L
Sbjct: 515 AQDEDVGINGLQNYSL-SPNPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELH-----L 568
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ A+ +P ++ A+V + +LD NDN+P F + Y + + EN P G V++V A D D
Sbjct: 569 VLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPD 628
Query: 335 QGENGE----FTYQLDDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+G NG+ FT + + + ++P +G + V + E
Sbjct: 629 EGSNGKVRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEE 670
Score = 60.1 bits (139), Expect = 5e-07
Identities = 61/195 (31%), Positives = 86/195 (44%), Gaps = 19/195 (9%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV N A ++ IPE+ P T + L+ D DSG NG R E E +P
Sbjct: 693 VEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDSGDNG--RTECAIEGDVPF 750
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVK 1036
S +A A N A +E+ ++I A D G L+ SV V +
Sbjct: 751 SLTAAFA---------NHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIA 801
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI------QPSDTD 1090
DVND+ P F + Y+ +V E + +G V ATDAD G N + Y + + D
Sbjct: 802 DVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPDVS 861
Query: 1091 LPFEISPLTGVLSVN 1105
L E PL+ V SV+
Sbjct: 862 LYAESRPLSVVRSVD 876
Score = 56.8 bits (131), Expect = 4e-06
Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Query: 218 IHAIDQDLGVGATLRYEL--ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G +RY +S ++L+ L+ G + + LD + E + L
Sbjct: 622 VSAADPDEGSNGKVRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHE-----LV 676
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
V+A ++ +A RV +E+LD+NDN PE + + SI E+ P V + D+D
Sbjct: 677 VRA--MDGGGLSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDS 734
Query: 336 GENGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
G+NG ++ FS+ + +R LDRE + + + A +
Sbjct: 735 GDNGRTECAIEGDV-PFSLTAAFANHYELRTSAALDRETTAEYNVSIVATD 784
Score = 51.2 bits (117), Expect = 2e-04
Identities = 55/236 (23%), Positives = 91/236 (38%), Gaps = 15/236 (6%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V V+D ND V + + V ENS + + + + G VR+
Sbjct: 588 VVVLDANDNMPVFSREVYE---VRVAENSPPGQL--VVRVSAADPDEGSNGKVRYTFTEM 642
Query: 724 QDVTDDI--AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
+ + + E G I LD E+ ++ + V A G+ + ++ + + D N
Sbjct: 643 SEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVH---VEVLDVN 699
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DN P ++ I E++ T + + + D D G N + G+
Sbjct: 700 DNAPEIALSSVSASIPEDAPPRTVVAL---LSVRDRDSGDNGRTECAIEGDVPFSLTAAF 756
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+LDRE Y +S+VA D G LS+ + + I D NDN P F Q
Sbjct: 757 ANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQ 812
Score = 48.8 bits (111), Expect = 0.001
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 4/108 (3%)
Query: 244 FSLDSVNGSLF-LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
FSL + + + L LD E + N ++ A+ +A+ V + + D+NDN
Sbjct: 750 FSLTAAFANHYELRTSAALDRETTAEYNVSIV---ATDWGRARLSARESVSVRIADVNDN 806
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG 350
P F Y++S+ EN + V ATD D G NG Y L +G
Sbjct: 807 APRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEG 854
Score = 48.0 bits (109), Expect = 0.002
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 9/166 (5%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + LDRE+ + + F + + + + + D ND+ PVF
Sbjct: 440 GVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEVVLE 499
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIG----D 851
++E + G+ +++ A D D G N L Y+L +++ G +F+
Sbjct: 500 VLETASPGSRFSLES---AQDEDVGINGLQNYSLSPNPYFSLALEKWKGGAEFVKLVLQK 556
Query: 852 SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
LDRE++ L L A D G S A++ +++ D NDN P F++
Sbjct: 557 PLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSR 602
Score = 46.4 bits (105), Expect = 0.006
Identities = 65/259 (25%), Positives = 107/259 (41%), Gaps = 28/259 (10%)
Query: 1093 FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
F + P +GVL+V LDRE + + DVND+SP F
Sbjct: 433 FRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVFP 492
Query: 1153 AFD---ELLEWKHPEAD-ELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIG 1208
+ E+LE P + L + E V + + ++ N P + + + +F+
Sbjct: 493 QKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLSPN-PYFSLALEKWKGGAEFV- 550
Query: 1209 NGNGLILYSLPQRKNQQNL---------GLPSLSSTAILMVTVADVPDEVEMSDKPVFIS 1259
L+L R+ Q+ L G P S TA + V V D D + PVF
Sbjct: 551 ---KLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNM-----PVFSR 602
Query: 1260 RYYELEIEENVNAPVEL---VSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY 1316
YE+ + EN + P +L VS + N K+R Y E ++ + ++P G +
Sbjct: 603 EVYEVRVAEN-SPPGQLVVRVSAADPDEGSNGKVR-YTFTEMSEQSQQLYELNPETGEIR 660
Query: 1317 LVRSPDREVKDTYEVIVRA 1335
+ + D E + +E++VRA
Sbjct: 661 VSGNLDYEEEKMHELVVRA 679
Score = 39.1 bits (87), Expect = 0.92
Identities = 43/173 (24%), Positives = 75/173 (43%), Gaps = 12/173 (6%)
Query: 221 IDQDLGVG----ATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ QDLG+ A + ++S + F LD +G L + + LD E + +
Sbjct: 406 VAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLD--RERICPHSESCALL 463
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
NP++ R E+E+ D+ND+ P F + ++E G A D+D G
Sbjct: 464 FKLFFENPVQLI--RGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVG 521
Query: 337 ENGEFTYQLD-DPKGAFSIDPRSG---WLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y L +P + +++ G ++ + Q LDRE L + + A +
Sbjct: 522 INGLQNYSLSPNPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATD 574
>UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor (Vascular
cadherin-2) (Vascular endothelial cadherin-2)
(VE-cadherin-2) (VE-cad-2).; n=2; Gallus gallus|Rep:
Protocadherin-12 precursor (Vascular cadherin-2)
(Vascular endothelial cadherin-2) (VE-cadherin-2)
(VE-cad-2). - Gallus gallus
Length = 1099
Score = 90.2 bits (214), Expect = 4e-16
Identities = 112/424 (26%), Positives = 175/424 (41%), Gaps = 53/424 (12%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
DG + T +DRE+ + F+ + V + + D ND+ P F E
Sbjct: 82 DGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTPELEL 141
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ E++ + I +D +A DAD G NA Y L E F ++ +G D
Sbjct: 142 EMSESASLQMHIPLD---RALDADTGPNAHCSYAL--SPSEHFALEVVSG-----SDGTK 191
Query: 855 REKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTA 914
+ ++ K V R+ L S +L++ D H E +GTA
Sbjct: 192 HAELVVIKE--VDRE---LHSSFDLVLTAAD-------------------HGEPPRSGTA 227
Query: 915 GFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEV 974
+I + + + + + + E+ +GT ++ + A D D G NG+I Y +
Sbjct: 228 LIKVIVLDSNDNSPVFAES-SLVVEVREDALLGTLLVTVTATDPDQGPNGEIEYSLSK-- 284
Query: 975 YIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD-GGN-LNDNIS 1030
+ PP LS F I+ R G V++ R L E + L++ A D G N + +
Sbjct: 285 HAPPEVLST--------FAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCK 336
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFN--VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
V V V DVND+ P + TW + EA + V A+D D G N + + P D
Sbjct: 337 VLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPGD 396
Query: 1089 TDLPF-EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDN 1147
+ + + +L N LDRE +Y LT+VARD G DVNDN
Sbjct: 397 EHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQG-EHSLAVWKHLTICISDVNDN 455
Query: 1148 SPKF 1151
+P F
Sbjct: 456 APSF 459
Score = 88.2 bits (209), Expect = 2e-15
Identities = 131/547 (23%), Positives = 222/547 (40%), Gaps = 42/547 (7%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
EQL + ++VEV +LD ND+ P F P+ E M +A + I +A+D D G N
Sbjct: 113 EQL-ALIHVEVQVLDINDHAPRF-PTPELELEMSESASLQMHIPLDRALDADTGPNAHCS 170
Query: 497 YDLQRTSN--LTITSPFKINPNTGTVSVAE-SPILEGRHALFVEASDQPANPSERRYSLA 553
Y L + + L + S + V + E L L + A+D P +
Sbjct: 171 YALSPSEHFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAADHGEPPRSGTALIK 230
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLL 611
V+ ++ + + P F + V + +GT + + D + ++ Y L
Sbjct: 231 VIVLD-------SNDNSPVFAESSLVVEVREDALLGTLLVTVTATDPDQGPNGEIEYSLS 283
Query: 612 -HGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVD 668
H E + FA++ R G + + L Y+ + A AN + V V+D
Sbjct: 284 KHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCKVLVRVLD 343
Query: 669 VNDERGVLLK--GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIA-NQQD 725
VND + A +P++ + A+ S G V ++ +
Sbjct: 344 VNDNAPDVRVTWAARAPVLSEAVPKDSFVAL-----VTASDPDSGNNGRVHCSLSPGDEH 398
Query: 726 VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ + T LDRE R Y +T++A ++G S A +TI I D NDN P
Sbjct: 399 FRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVAR-DQGEHSLAVWKHLTICISDVNDNAP 457
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTG 844
FE +YE + EN + + ++ATD D G N Y++ + +D +G
Sbjct: 458 SFERTSYERAVEENGDVPAFLL---TVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPISG 514
Query: 845 VVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKV 902
+ + + D E+ + + A D G L+S + + + D+NDN P + E V
Sbjct: 515 DITAL-RAFDHEQMSSLEFLVTAEDGGHPVLASNVTVRLEVLDQNDNAP---VVTEPPLV 570
Query: 903 RIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGL 962
R + +A + V N A++ + + P+ TI+ A D DSG
Sbjct: 571 RGMATLSVLVSAETGCVWVTSGNGSAMETVLAN---VSCSDTPLLFTIV---ARDGDSGR 624
Query: 963 NGQIRYE 969
NG +RY+
Sbjct: 625 NGALRYD 631
Score = 73.7 bits (173), Expect = 3e-11
Identities = 138/539 (25%), Positives = 210/539 (38%), Gaps = 70/539 (12%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLS-ADALEVKRYFVINERHGHVIVARSLPPESEF 1013
ALD D+G N Y + + +S +D + VI E V R L S F
Sbjct: 158 ALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIKE------VDREL--HSSF 209
Query: 1014 RLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATD 1071
L ++A D G + ++V V D ND+ PVF ++ V E +L V ATD
Sbjct: 210 DLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLGTLLVTVTATD 269
Query: 1072 ADFGQNANLTYFIQ---PSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D G N + Y + P + F I G + + LD E Y L V ARD G
Sbjct: 270 PDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGAN 329
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW--KHPEADELSNHNFESVMMIPVYKATI 1186
DVNDN+P D + W + P E + V ++
Sbjct: 330 PIPAHCKVLVRVL-DVNDNAP-----DVRVTWAARAPVLSEAVPKD-SFVALVTASDPDS 382
Query: 1187 EENAPIGTTVA---KVF----ANDTDFIGNGNGLILYSLPQRKN----QQNLGLPSLSST 1235
N + +++ + F N ++ N ++ L N ++ G SL+
Sbjct: 383 GNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQGEHSLAVW 442
Query: 1236 AILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENF--KMRYY 1293
L + ++DV D P F YE +EEN + P L+++ T+ F K+ Y
Sbjct: 443 KHLTICISDVNDNA-----PSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYS 497
Query: 1294 ILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
I D+ + IDP +G + +R+ D E + E +V AE +PV
Sbjct: 498 I---RDSTVLGLVSIDPISGDITALRAFDHEQMSSLEFLVTAEDGG---------HPVLA 545
Query: 1354 DVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPT 1413
+V V + + D NDN+P T PLV + T + + +
Sbjct: 546 S--------NVTVRLEVLDQNDNAPVVT--EPPLVRGMATLSVLVSAETGCVWVTSGNGS 595
Query: 1414 ASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRYQIL-NEQAPRFAIDPVSG 1471
A TV A+ V L L + A D D G N +RY I+ + A +DP+SG
Sbjct: 596 AMETVLAN----VSCSDTPL--LFTIVARDGDSGRNGALRYDIMGGDAAGLVVLDPLSG 648
Score = 63.3 bits (147), Expect = 5e-08
Identities = 48/171 (28%), Positives = 78/171 (45%), Gaps = 8/171 (4%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A+D D G A Y L L + +G+ E + + + L ++ F L + A+
Sbjct: 158 ALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIKEVDRELHSS-FDLVLTAA 216
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG 339
P ++ A +++ +LD NDN P F + + E+ G ++ V ATD DQG NG
Sbjct: 217 DHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLGTLLVTVTATDPDQGPNG 276
Query: 340 EFTYQLD-----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
E Y L + F+ID R G + +R LD E + + V A++
Sbjct: 277 EIEYSLSKHAPPEVLSTFAIDARMGSVVLRRP--LDYEETHAYELDVQARD 325
Score = 60.1 bits (139), Expect = 5e-07
Identities = 58/179 (32%), Positives = 79/179 (44%), Gaps = 10/179 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNG-SLFLEKELDLDAEHNLQANTFVLQV 276
+ A D D G + L G++ F L N S L LD E L+A + V
Sbjct: 375 VTASDPDSGNNGRVHCSLSPGDEH--FRLKQTNSHSYLLMTNAMLDRE--LRAEYNLTLV 430
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
Q + L + + I + D+NDN P FE Y ++ EN +L V ATD D G
Sbjct: 431 ARDQGEHSLAVWK-HLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLG 489
Query: 337 ENGEFTYQLDDPK--GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
NG+ TY + D G SIDP SG +T D E SSL V A++ V+ +
Sbjct: 490 FNGKVTYSIRDSTVLGLVSIDPISGDITALR--AFDHEQMSSLEFLVTAEDGGHPVLAS 546
Score = 57.6 bits (133), Expect = 2e-06
Identities = 49/175 (28%), Positives = 78/175 (44%), Gaps = 13/175 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL---FSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
+ A D D G + Y L ++ F++D+ GS+ L + LD + H + L
Sbjct: 265 VTATDPDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETH-----AYEL 319
Query: 275 QVQASQLN-NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIV--ENLPNGFSVLQVMAT 331
VQA L NP+ A +V + +LD+NDN P+ V + + V E +P V V A+
Sbjct: 320 DVQARDLGANPIP-AHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTAS 378
Query: 332 DKDQGENGEFTYQLDDPKGAFSI-DPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D G NG L F + S + +LDRE + + + A++
Sbjct: 379 DPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARD 433
Score = 57.6 bits (133), Expect = 2e-06
Identities = 54/213 (25%), Positives = 86/213 (40%), Gaps = 13/213 (6%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ E +P + + + A D DSG NG++ + Y ++
Sbjct: 361 VLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPG----DEHFRLKQTNSHSYLLMT--- 413
Query: 999 GHVIVARSLPPESEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
+ ++ R L +E+ L + A D G + + + + + DVND+ P F++T Y VEE
Sbjct: 414 -NAMLDREL--RAEYNLTLVARDQGEHSLAVWKHLTICISDVNDNAPSFERTSYERAVEE 470
Query: 1057 AQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
L V ATD D G N +TY I+ S I P++G ++ D E
Sbjct: 471 NGDVPAFLLTVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPISGDITALRAFDHEQMSSL 530
Query: 1117 ILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
V A D G D NDN+P
Sbjct: 531 EFLVTAEDGG-HPVLASNVTVRLEVLDQNDNAP 562
Score = 48.0 bits (109), Expect = 0.002
Identities = 27/86 (31%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
+ L + ++ + + D NDN P F ++ YE +++ N V + V+A DPDLG NG V
Sbjct: 436 EHSLAVWKHLTICISDVNDNAPSFERTS-YERAVEENGDVPAFLLTVRATDPDLGFNGKV 494
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVS 521
Y ++ ++ L + S I+P +G ++
Sbjct: 495 TYSIRDSTVLGLVS---IDPISGDIT 517
Score = 39.9 bits (89), Expect = 0.53
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 6/103 (5%)
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
A VE+++LD+ND+ P F + + E+ + A D D G N +Y L
Sbjct: 116 ALIHVEVQVLDINDHAPRFPTPELELEMSESASLQMHIPLDRALDADTGPNAHCSYAL-S 174
Query: 348 PKGAFSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE 385
P F+++ SG ++ + +DRE HSS + + A +
Sbjct: 175 PSEHFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAAD 217
Score = 39.1 bits (87), Expect = 0.92
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A D DLG + Y + L S+D ++G + + D + Q ++ V
Sbjct: 481 VRATDPDLGFNGKVTYSIRDSTVLGLVSIDPISGDITALRAFDHE-----QMSSLEFLVT 535
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLP 304
A +P+ + V +E+LD NDN P
Sbjct: 536 AEDGGHPVLASNVTVRLEVLDQNDNAP 562
>UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 16
SCAF15002, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 421
Score = 89.8 bits (213), Expect = 5e-16
Identities = 60/189 (31%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 214 FP-EPIHAIDQDLGVGATLRYELISGNDRKLFSLDS---VNGSLFLEKELDLDAEHNLQA 269
FP EP A+D D G T Y + GN + F+L++ NG L+L+ ++ + +
Sbjct: 6 FPLEP--AVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDRE-KR 62
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+T+ L ++A +P +T ++I + D+NDN P F Y+ I ENL G ++LQV
Sbjct: 63 STYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVF 122
Query: 330 ATDKDQGENGEFTYQLD----DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
ATD D+G+NG+ Y+++ DP F ID +SG +T+ + + L ++
Sbjct: 123 ATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNA 182
Query: 386 TNPSVVGTF 394
T P V F
Sbjct: 183 TQPEVSNAF 191
Score = 88.6 bits (210), Expect = 1e-15
Identities = 97/356 (27%), Positives = 163/356 (45%), Gaps = 34/356 (9%)
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLL 611
V+++++T + + P F + Y + N+ G+++ Q+ D E ++ V Y++
Sbjct: 82 VMSLDIT--VQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGDNGKVLYEIN 139
Query: 612 HGYEEGVP-FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA--TVHVVD 668
+ F ++ +SGVIT+ L + +++ V Q+NA V+NA T+HV D
Sbjct: 140 RRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHEL-VVQAQDNATQPEVSNAFVTIHVRD 198
Query: 669 VNDERGVLLKGAHSPIIFHVKENSA----GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ 724
ND + + IIF ++ S GA GQ + S+ G + + +
Sbjct: 199 YNDNQPTMT------IIFLSEDGSPRVSEGAQPGQ--YVARISVTDPDYGEYANVNVSLE 250
Query: 725 DVTDDIAIA-EDGTIF---TQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDE 780
A+ +D I+ + LDRE+RD Y + V+A + G I + D
Sbjct: 251 GGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMAT-DSGTPPLRAESSFIIQVTDV 309
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMF 837
NDNPP+F+ Y I E G+ + + A D D G N Y+LF G + F
Sbjct: 310 NDNPPLFDQPVYRQVIPEVVFPGSFVLQ---VTARDKDHGPNGDITYSLFQDQGAHSKWF 366
Query: 838 DVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+D TG++ LD EK +++VA D G +SS A + I++ D NDN+P
Sbjct: 367 SIDSVTGIIT-TDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVLQDINDNEP 421
Score = 78.6 bits (185), Expect = 1e-12
Identities = 83/317 (26%), Positives = 138/317 (43%), Gaps = 28/317 (8%)
Query: 81 LSVTVYIEDVNDNVPIFLDTPYHVTVDE-LTPTGEKAFIFLIAPI-GPSLTIPLTVPRG- 137
+S+ + ++D+NDN P+F + YH + E L P +F G + + + R
Sbjct: 83 MSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGDNGKVLYEINRRQ 142
Query: 138 ------LTIFKDIRAFDRDKP-NTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDY 190
I +KP + VH +V D+ A + + V DY
Sbjct: 143 SDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDN---ATQPEVSNAFVTIHVRDY 199
Query: 191 DAGDKEFQLVIMAS--GKRIHKEIL---FPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
+ ++ ++ R+ + + I D D G A + L G D K F+
Sbjct: 200 NDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYANVNVSL-EGGDGK-FA 257
Query: 246 LDSVNGSLFLE-KELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLP 304
L + + ++L + LD E + +T+ L+V A+ P A++ I++ D+NDN P
Sbjct: 258 LTTKDNIIYLICVDRILDRE---ERDTYELRVMATDSGTPPLRAESSFIIQVTDVNDNPP 314
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA----FSIDPRSGW 360
F+ Y I E + G VLQV A DKD G NG+ TY L +GA FSID +G
Sbjct: 315 LFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQDQGAHSKWFSIDSVTGI 374
Query: 361 LTVRNQTVLDREAHSSL 377
+T +Q ++ + S+
Sbjct: 375 ITTDSQLDYEKNPNPSI 391
Score = 77.4 bits (182), Expect = 3e-12
Identities = 78/272 (28%), Positives = 121/272 (44%), Gaps = 21/272 (7%)
Query: 635 LSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-S 692
L R R Y A + + V + + V D+ND V + + II EN
Sbjct: 57 LDREKRSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAII---SENLQ 113
Query: 693 AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI--AEDGTIFTQKPLDREKRD 750
G+ I Q+F T+ G V + I +Q D + ++ G I KPLD E +
Sbjct: 114 PGSNILQVFATDDDE---GDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKR 170
Query: 751 VYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP----VFEHATYEGFIMENSKIGTEI 806
V+ + V A+ N + + VTI++ D NDN P +F + E ++ G +
Sbjct: 171 VHELVVQAQDNATQPEVSNAF-VTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYV 229
Query: 807 KMDNIIKATDADEGTNALFMYTLFG-EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
I TD D G A +L G +GK +N + + LDRE++ Y+L +
Sbjct: 230 AR---ISVTDPDYGEYANVNVSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRV 286
Query: 866 VARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
+A D+G L +E+ II + D NDN P F+Q
Sbjct: 287 MATDSGTPPLRAESSFIIQVTDVNDNPPLFDQ 318
Score = 75.8 bits (178), Expect = 9e-12
Identities = 104/378 (27%), Positives = 169/378 (44%), Gaps = 31/378 (8%)
Query: 423 DKVGTKTENIEYYD---EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVI 479
+K T T ++E +D + +++++T+ D NDN PVF S Y + N + G+ I
Sbjct: 60 EKRSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSR-YHAIISENLQPGSNI 118
Query: 480 GKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVE 537
+V A D D G NG VLY++ R + F I+ +G +++ + E + H L V+
Sbjct: 119 LQVFATDDDEGDNGKVLYEINRRQS-DPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQ 177
Query: 538 ASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIR 596
A D N ++ S A VTI V R N+P + F+ V G V +I
Sbjct: 178 AQD---NATQPEVSNAFVTIHV-RDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARIS 233
Query: 597 VNDA--FEQNDVSYDLLHGYEEGVPFAVEERSGVITV--VDD-LSRYNRPMYDFEAVALQ 651
V D E +V+ L G +G FA+ + +I + VD L R R Y+ +A
Sbjct: 234 VTDPDYGEYANVNVSLEGG--DG-KFALTTKDNIIYLICVDRILDREERDTYELRVMATD 290
Query: 652 ENA-NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG 710
L ++ + V DVND + + + +I V G+ + Q+ T +G
Sbjct: 291 SGTPPLRAESSFIIQVTDVNDNPPLFDQPVYRQVIPEVV--FPGSFVLQV--TARDKDHG 346
Query: 711 NGTGNVRFLIANQQDVTDD-IAI-AEDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISG 767
G++ + + Q +I + G I T LD EK +TV+A + K +S
Sbjct: 347 -PNGDITYSLFQDQGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSS 405
Query: 768 AGIYQVTIYIEDENDNPP 785
+ V I ++D NDN P
Sbjct: 406 TAL--VNIVLQDINDNEP 421
Score = 73.3 bits (172), Expect = 5e-11
Identities = 62/222 (27%), Positives = 98/222 (44%), Gaps = 21/222 (9%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
+I EN+ G+ I+++ A D D G NG++ YE N P RYFVI+ +
Sbjct: 107 IISENLQPGSNILQVFATDDDEGDNGKVLYEINRRQSDP-----------DRYFVIDSQS 155
Query: 999 GHVIVARSLPPESE--FRLNISALDGGNLND--NISVRVFVKDVNDHFP----VFKKTWY 1050
G + + + L E + L + A D + N V + V+D ND+ P +F
Sbjct: 156 GVITLNKPLDFEMKRVHELVVQAQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDG 215
Query: 1051 NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP-LTGVLSVNGELD 1109
+ V E + + ++ TD D+G+ AN+ ++ D + ++ V+ LD
Sbjct: 216 SPRVSEGAQPGQYVARISVTDPDYGEYANVNVSLEGGDGKFALTTKDNIIYLICVDRILD 275
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
RE D Y L V+A D+G DVNDN P F
Sbjct: 276 REERDTYELRVMATDSG-TPPLRAESSFIIQVTDVNDNPPLF 316
Score = 68.9 bits (161), Expect = 1e-09
Identities = 47/143 (32%), Positives = 72/143 (50%), Gaps = 5/143 (3%)
Query: 1011 SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVD 1068
S + L++ A DGG+ D +S+ + V+D+ND+ PVF ++ Y+ + E + +V
Sbjct: 63 STYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVF 122
Query: 1069 ATDADFGQNANLTYFI--QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
ATD D G N + Y I + SD D F I +GV+++N LD E + + L V A+DN
Sbjct: 123 ATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDN- 181
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSP 1149
D NDN P
Sbjct: 182 ATQPEVSNAFVTIHVRDYNDNQP 204
Score = 61.3 bits (142), Expect = 2e-07
Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L + A D G L S + V DVND+ P+F + Y + E + + +V A
Sbjct: 282 YELRVMATDSGTPPLRAESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTAR 341
Query: 1071 DADFGQNANLTY--FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D D G N ++TY F F I +TG+++ + +LD E +TVVA D G
Sbjct: 342 DKDHGPNGDITYSLFQDQGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGG-K 400
Query: 1129 XXXXXXXXXXXXXXDVNDNSP 1149
D+NDN P
Sbjct: 401 PPMSSTALVNIVLQDINDNEP 421
Score = 53.2 bits (122), Expect = 5e-05
Identities = 44/176 (25%), Positives = 77/176 (43%), Gaps = 12/176 (6%)
Query: 218 IHAIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D G + YE+ + + F +DS +G + L K LD + + + + V+Q
Sbjct: 121 VFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMK---RVHELVVQ 177
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNIS----IVENLPNGFSVLQVMAT 331
Q P + + A V I + D NDN P + F + + E G V ++ T
Sbjct: 178 AQ-DNATQP-EVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVT 235
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKET 386
D D GE L+ G F++ + + + +LDRE + ++V A ++
Sbjct: 236 DPDYGEYANVNVSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMATDS 291
Score = 50.8 bits (116), Expect = 3e-04
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 14/173 (8%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P + L +TV D+ D PVF Y I EN+ ++ + T+ E
Sbjct: 75 GSPKRTDVMSLDITVQDINDNA-----PVFNQSRYHAIISENLQPGSNILQVFATDDDEG 129
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N K+ Y I N +D R FVID ++G + L + D E+K +E++V+A+ E+
Sbjct: 130 DNGKVLYEI-NRRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNATQPEVS 188
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRP--LVTAIPTTAP 1396
+ V V + ++ + + D SP+ + G +P V I T P
Sbjct: 189 NAF--VTIHVRDYNDNQPTMTIIFLSE--DGSPRVSEGAQPGQYVARISVTDP 237
>UniRef50_Q4S7A7 Cluster: Chromosome 1 SCAF14716, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 1
SCAF14716, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 344
Score = 89.4 bits (212), Expect = 7e-16
Identities = 71/238 (29%), Positives = 112/238 (47%), Gaps = 14/238 (5%)
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVD 668
L G G F +++ +G I + L R +P Y A A+ N N L + + V D
Sbjct: 98 LSGDGAGSIFTIDQTTGDIHALRSLDREEKPYYTLRAQAVDINTNRPLEPESEFVIKVQD 157
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDVT 727
+ND L+G + + + + G + Q+ T+ YGN V ++ Q +
Sbjct: 158 INDNEPKFLEGPYRASVPEM--SPVGTYVTQVTATDADDPTYGNSARVVYSILHGQPYFS 215
Query: 728 DDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNPP 785
D + G I T P +DRE ++ Y++ + A+ G + G AG V I + D NDNPP
Sbjct: 216 VD---PKTGVIKTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTTVNITLSDVNDNPP 272
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDEN 842
F + + + E+S +G+ + IKA D D G NA YT+ G+G MFD+ N
Sbjct: 273 RFSKSFFHLRVPESSAVGSAV---GRIKAHDLDIGRNAEVEYTIVPGDGGNMFDITTN 327
Score = 78.2 bits (184), Expect = 2e-12
Identities = 50/164 (30%), Positives = 77/164 (46%), Gaps = 5/164 (3%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I + LDRE++ Y + A + I ++D NDN P F Y
Sbjct: 114 GDIHALRSLDREEKPYYTLRAQAVDINTNRPLEPESEFVIKVQDINDNEPKFLEGPYRAS 173
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E S +GT + A D G +A +Y++ G+ F VD TGV+K ++DR
Sbjct: 174 VPEMSPVGTYVTQVTATDADDPTYGNSARVVYSIL-HGQPYFSVDPKTGVIKTALPNMDR 232
Query: 856 EKKIMYKLSLVARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
E K Y++ + A+D GGL+ + I + D NDN P F++
Sbjct: 233 EVKEQYQVLIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFSK 276
Score = 64.9 bits (151), Expect = 2e-08
Identities = 60/250 (24%), Positives = 106/250 (42%), Gaps = 16/250 (6%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D G A ++Y L +F++D G + + LD + + + L+ QA +
Sbjct: 86 DLDKGDSA-VKYTLSGDGAGSIFTIDQTTGDIHALRSLDRE-----EKPYYTLRAQAVDI 139
Query: 282 NN--PLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ---G 336
N PL+ ++ I++ D+NDN P+F Y S+ E P G V QV ATD D G
Sbjct: 140 NTNRPLEP-ESEFVIKVQDINDNEPKFLEGPYRASVPEMSPVGTYVTQVTATDADDPTYG 198
Query: 337 ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN---PSVVGT 393
+ Y + + FS+DP++G + +DRE ++ + AK+ + GT
Sbjct: 199 NSARVVYSILHGQPYFSVDPKTGVIKTALPN-MDREVKEQYQVLIQAKDMGGQLGGLAGT 257
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
+ ++ P + VG+ I+ +D + VE T++ +
Sbjct: 258 TTVNITLSDVNDNPPRFSKSFFHLRVPESSAVGSAVGRIKAHDLDIGRNAEVEYTIVPGD 317
Query: 454 DNNPVFVPSN 463
N + +N
Sbjct: 318 GGNMFDITTN 327
Score = 61.7 bits (143), Expect = 2e-07
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
F I++ G + RSL E + + L A+D L + V+D+ND+ P F
Sbjct: 107 FTIDQTTGDIHALRSLDREEKPYYTLRAQAVDINTNRPLEPESEFVIKVQDINDNEPKFL 166
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
+ Y +V E + +V ATDAD +G +A + Y I F + P TGV+
Sbjct: 167 EGPYRASVPEMSPVGTYVTQVTATDADDPTYGNSARVVYSILHGQPY--FSVDPKTGVIK 224
Query: 1104 VN-GELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+DRE +++Y + + A+D G DVNDN P+F
Sbjct: 225 TALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRF 274
Score = 61.3 bits (142), Expect = 2e-07
Identities = 52/195 (26%), Positives = 95/195 (48%), Gaps = 33/195 (16%)
Query: 921 VKPKNKFALDVDQLG---PLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
++P+++F + V + P FL +PE P+GT + ++ A D D G
Sbjct: 145 LEPESEFVIKVQDINDNEPKFLEGPYRASVPEMSPVGTYVTQVTATDADDPTYG------ 198
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP-----ESEFRLNISALD-GGN 1024
NS +++ L + YF ++ + G ++ +LP + ++++ I A D GG
Sbjct: 199 NS------ARVVYSILHGQPYFSVDPKTG--VIKTALPNMDREVKEQYQVLIQAKDMGGQ 250
Query: 1025 LND---NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
L +V + + DVND+ P F K++++ V E+ +G++ A D D G+NA +
Sbjct: 251 LGGLAGTTTVNITLSDVNDNPPRFSKSFFHLRVPESSAVGSAVGRIKAHDLDIGRNAEVE 310
Query: 1082 YFIQPSDTDLPFEIS 1096
Y I P D F+I+
Sbjct: 311 YTIVPGDGGNMFDIT 325
Score = 46.4 bits (105), Expect = 0.006
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 18/114 (15%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
F ID G ++ +RS DRE K Y + RA+ + P LE +++
Sbjct: 107 FTIDQTTGDIHALRSLDREEKPYYTL--RAQAVDINTNRP----------LEPESEF--- 151
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
V++++D+NDN PKF G P ++P +P G V Q+ PT + R
Sbjct: 152 -VIKVQDINDNEPKFLEG--PYRASVPEMSPVGTYVTQVTATDADDPTYGNSAR 202
Score = 45.6 bits (103), Expect = 0.011
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 8/138 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A + Y ++ G + FS+D G + ++D E Q + + +QA
Sbjct: 192 ADDPTYGNSARVVYSILHG--QPYFSVDPKTGVIKTALP-NMDREVKEQ---YQVLIQAK 245
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ L V I L D+NDN P F F+++ + E+ G +V ++ A D D G
Sbjct: 246 DMGGQLGGLAGTTTVNITLSDVNDNPPRFSKSFFHLRVPESSAVGSAVGRIKAHDLDIGR 305
Query: 338 NGEFTYQLDDPKGAFSID 355
N E Y + G D
Sbjct: 306 NAEVEYTIVPGDGGNMFD 323
Score = 45.2 bits (102), Expect = 0.014
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V +TL D NDN P F S + + ++ VG+ +G++KA D D+G+N V Y
Sbjct: 254 LAGTTTVNITLSDVNDNPPRFSKS-FFHLRVPESSAVGSAVGRIKAHDLDIGRNAEVEYT 312
Query: 499 L 499
+
Sbjct: 313 I 313
Score = 43.6 bits (98), Expect = 0.043
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 19/175 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV---DPDLGQNGMVLYDLQRTS 503
+ + D NDN P F+ Y S+ + VGT + +V A DP G + V+Y +
Sbjct: 153 IKVQDINDNEPKFLEGP-YRASVPEMSPVGTYVTQVTATDADDPTYGNSARVVYSI---- 207
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F ++P TG + A + ++ ++ + ++A D + T+ +T
Sbjct: 208 -LHGQPYFSVDPKTGVIKTALPNMDREVKEQYQVLIQAKDM---GGQLGGLAGTTTVNIT 263
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQN-DVSYDLLHG 613
+ P P F + + V + +G++VG+I+ +D +N +V Y ++ G
Sbjct: 264 LSDVNDNP--PRFSKSFFHLRVPESSAVGSAVGRIKAHDLDIGRNAEVEYTIVPG 316
Score = 39.1 bits (87), Expect = 0.92
Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 10/137 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-----DVSYDLLHGYEEGVPFAVEER 625
P F+ PY V +GT V Q+ DA + V Y +LHG F+V+ +
Sbjct: 163 PKFLEGPYRASVPEMSPVGTYVTQVTATDADDPTYGNSARVVYSILHGQPY---FSVDPK 219
Query: 626 SGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+GVI T + ++ R + Y A L + T + ++D + + S
Sbjct: 220 TGVIKTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFSKSFF 279
Query: 685 IFHVKENSA-GAAIGQI 700
V E+SA G+A+G+I
Sbjct: 280 HLRVPESSAVGSAVGRI 296
Score = 37.9 bits (84), Expect = 2.1
Identities = 13/29 (44%), Positives = 21/29 (72%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ ++D+NDN P FL+ PY +V E++P G
Sbjct: 153 IKVQDINDNEPKFLEGPYRASVPEMSPVG 181
Score = 35.9 bits (79), Expect = 8.6
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 1/82 (1%)
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
TD D G +A + Y + F I TG + LDRE + Y L A D
Sbjct: 85 TDLDKGDSA-VKYTLSGDGAGSIFTIDQTTGDIHALRSLDREEKPYYTLRAQAVDINTNR 143
Query: 1130 XXXXXXXXXXXXXDVNDNSPKF 1151
D+NDN PKF
Sbjct: 144 PLEPESEFVIKVQDINDNEPKF 165
>UniRef50_Q4SGA8 Cluster: Chromosome 17 SCAF14597, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF14597, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 764
Score = 88.6 bits (210), Expect = 1e-15
Identities = 113/452 (25%), Positives = 190/452 (42%), Gaps = 44/452 (9%)
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
G GN++++++ + T + + G I K LDRE++ Y +T A
Sbjct: 55 GNGNIKYILSGEGAGTIFVIDDKTGNIHATKTLDREEQAQYTLTAQAVDRHTNKPLEPPS 114
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+ + ++D NDNPP F H Y + E S + E+ I A G +A+ + T
Sbjct: 115 EFIVKVQDINDNPPEFLHGPYYARVPEMSNV--EVPSPLISAA-----GEDAMTVNTKLH 167
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
+ + F +D K + L+ T G+ +++ + G E +
Sbjct: 168 KIRRR-------AYSSFQNQYMDERKTGLIPERLLKSLTDGVKEDSDYLFRRGQER-GRV 219
Query: 892 EFNQIEENSKVRI-HRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTI 950
E + +N K+ + R+TK N P + + V + + +P G +
Sbjct: 220 ERKRERKNWKITLAKRKTKPN-----------PDTVYQMSVSE--------DKVP-GEEV 259
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVAR--SLP 1008
+L A D D G NG + Y F + +LS D+ E K + ++ R +L
Sbjct: 260 GRLMAKDPDLGDNGHVNYRFVDGDGMAVFELSTDS-ETKEAIIKLKKPVDYENKRLYTLK 318
Query: 1009 PE-SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKV 1067
E S ++ L G D ++++ V+D D PVF Y F VEE V+G+V
Sbjct: 319 VEGSNPHIDPQFLAWGPYKDEATIKISVEDA-DEPPVFIAPSYTFEVEENAPPGTVVGRV 377
Query: 1068 DATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNG 1126
A D D N + Y I Q +D + F I+ G+++ LDRET+ + ++V A + G
Sbjct: 378 HAKDTDIAVNP-IRYMIPQYTDIERFFSINSEDGLITTTKPLDRETQAWHNISVSATEIG 436
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELL 1158
DVNDN P+F +E+L
Sbjct: 437 -GHHQDTKVRVNIRVKDVNDNPPEFATNNEVL 467
Score = 62.5 bits (145), Expect = 9e-08
Identities = 112/467 (23%), Positives = 194/467 (41%), Gaps = 54/467 (11%)
Query: 447 VTLLDANDNNPVFVPSNLY-EFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNL 505
V + D NDN P F+ Y SN +V + + + A D L+ ++R +
Sbjct: 118 VKVQDINDNPPEFLHGPYYARVPEMSNVEVPSPL--ISAAGEDAMTVNTKLHKIRRRAYS 175
Query: 506 TITSPFKINPNTGTV------SVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEV 559
+ + + TG + S+ + + E LF ++ +R +T+
Sbjct: 176 SFQNQYMDERKTGLIPERLLKSLTDG-VKEDSDYLFRRGQERGRVERKRERKNWKITL-A 233
Query: 560 TRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEG 617
R TK N PD + Y+ V + G VG++ D + V+Y + G
Sbjct: 234 KRKTKPN----PDTV---YQMSVSEDKVPGEEVGRLMAKDPDLGDNGHVNYRFVDGDGMA 286
Query: 618 VPFAV----EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT------NATVHV- 666
V F + E + +I + + N+ +Y + + + + AT+ +
Sbjct: 287 V-FELSTDSETKEAIIKLKKPVDYENKRLYTLKVEGSNPHIDPQFLAWGPYKDEATIKIS 345
Query: 667 VDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD 725
V+ DE V + +++ F V+EN+ G +G++ H + I N +R++I D
Sbjct: 346 VEDADEPPVFIAPSYT---FEVEENAPPGTVVGRV-HAKDTDIAVNP---IRYMIPQYTD 398
Query: 726 VTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ +I +EDG I T KPLDRE + + ++V A G + +V I ++D NDNP
Sbjct: 399 IERFFSINSEDGLITTTKPLDRETQAWHNISVSATEIGGHHQDTKV-RVNIRVKDVNDNP 457
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGE--GKEMFDVDE 841
P F E + E++ G K+ I A D DE G F ++L E F + +
Sbjct: 458 PEFA-TNNEVLMCESAMPG---KIIETISAVDKDEMGHRQHFSFSLAAEVAHNHNFSIKD 513
Query: 842 N---TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
N T V + R + +Y L + D G +SS L I +
Sbjct: 514 NRDSTASVVVLRKGFSRLTQDVYHLPIEINDNGFPAMSSTNTLTIRV 560
Score = 51.6 bits (118), Expect = 2e-04
Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 13/132 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGND-RKLFSLDSVNGSLFLEKELDLDAE--HNLQANTFVL 274
+HA D D+ V +RY + D + FS++S +G + K LD + + HN+
Sbjct: 377 VHAKDTDIAVNP-IRYMIPQYTDIERFFSINSEDGLITTTKPLDRETQAWHNIS------ 429
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
V A+++ + + RV I + D+NDN PEF + + + E+ G + + A DKD
Sbjct: 430 -VSATEIGGHHQDTKVRVNIRVKDVNDNPPEFATN-NEVLMCESAMPGKIIETISAVDKD 487
Query: 335 Q-GENGEFTYQL 345
+ G F++ L
Sbjct: 488 EMGHRQHFSFSL 499
Score = 46.0 bits (104), Expect = 0.008
Identities = 49/149 (32%), Positives = 69/149 (46%), Gaps = 23/149 (15%)
Query: 1243 ADVPDEVEMSDKP-VFISRYYELEIEENV--NAPVELVSLNLTEHYENFKMRYYILNEND 1299
A + VE +D+P VFI+ Y E+EEN V V T+ N +RY I
Sbjct: 340 ATIKISVEDADEPPVFIAPSYTFEVEENAPPGTVVGRVHAKDTDIAVN-PIRYMI--PQY 396
Query: 1300 TDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGM 1359
TDI R F I+ +G + + DRE + + + V A I +D
Sbjct: 397 TDIERFFSINSEDGLITTTKPLDRETQAWHNISVSATE----------IGGHHQD----- 441
Query: 1360 TKYDVKVVVRIKDVNDNSPKFTNGNRPLV 1388
TK V+V +R+KDVNDN P+F N L+
Sbjct: 442 TK--VRVNIRVKDVNDNPPEFATNNEVLM 468
Score = 45.2 bits (102), Expect = 0.014
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 815 TDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD---T 870
+D D G N Y L GEG +F +D+ TG + +LDRE++ Y L+ A D
Sbjct: 50 SDVDTG-NGNIKYILSGEGAGTIFVIDDKTGNIHAT-KTLDREEQAQYTLTAQAVDRHTN 107
Query: 871 GGLSSEAELIIMIGDENDNKPEF 893
L +E I+ + D NDN PEF
Sbjct: 108 KPLEPPSEFIVKVQDINDNPPEF 130
Score = 42.7 bits (96), Expect = 0.075
Identities = 46/173 (26%), Positives = 65/173 (37%), Gaps = 20/173 (11%)
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
T Y +V E + +G++ A D D G N ++ Y D FE+S
Sbjct: 243 TVYQMSVSEDKVPGEEVGRLMAKDPDLGDNGHVNYRFVDGDGMAVFELST---------- 292
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
D ET++ I D D + Y + ++ +ADE
Sbjct: 293 -DSETKEAIIKLKKPVDYENKRLYTLKVEGSNPHIDPQFLAWGPYKDEATIKISVEDADE 351
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQ 1220
V + P Y +EENAP GT V +V A DTD N I Y +PQ
Sbjct: 352 ------PPVFIAPSYTFEVEENAPPGTVVGRVHAKDTDIAVNP---IRYMIPQ 395
Score = 41.5 bits (93), Expect = 0.17
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 1049 WYNFNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
W F V E +YT ++G++ + D D G N N+ Y + F I TG +
Sbjct: 28 WNQFFVIE-EYTGPDPVLVGRLHS-DVDTG-NGNIKYILSGEGAGTIFVIDDKTGNIHAT 84
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE + +Y LT A D D+NDN P+F
Sbjct: 85 KTLDREEQAQYTLTAQAVDRHTNKPLEPPSEFIVKVQDINDNPPEF 130
Score = 41.5 bits (93), Expect = 0.17
Identities = 49/178 (27%), Positives = 73/178 (41%), Gaps = 19/178 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSL--DSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
A D DLG + Y + G+ +F L DS ++ + +D E+ + L+V+
Sbjct: 264 AKDPDLGDNGHVNYRFVDGDGMAVFELSTDSETKEAIIKLKKPVDYENK---RLYTLKVE 320
Query: 278 ASQLN--------NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
S + P K +A ++I + D D P F Y + EN P G V +V
Sbjct: 321 GSNPHIDPQFLAWGPYKD-EATIKISVEDA-DEPPVFIAPSYTFEVEENAPPGTVVGRVH 378
Query: 330 ATDKDQGEN--GEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A D D N Q D + FSI+ G +T LDRE + + V A E
Sbjct: 379 AKDTDIAVNPIRYMIPQYTDIERFFSINSEDGLITTTKP--LDRETQAWHNISVSATE 434
Score = 35.9 bits (79), Expect = 8.6
Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 13/117 (11%)
Query: 380 KVYAKETNPSV------VGTFADSQRIAKWRRQP--LETNAPLEKTTYVFPDKVGTKTEN 431
+V+AK+T+ +V + + D +R + + T PL++ T + + + TE
Sbjct: 376 RVHAKDTDIAVNPIRYMIPQYTDIERFFSINSEDGLITTTKPLDRETQAWHNISVSATEI 435
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
++ + + V V + + D NDN P F +N E M +A G +I + AVD D
Sbjct: 436 GGHHQD---TKVRVNIRVKDVNDNPPEFATNN--EVLMCESAMPGKIIETISAVDKD 487
>UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|Rep:
Type II cadherin - Ciona savignyi (Pacific transparent
sea squirt)
Length = 910
Score = 88.6 bits (210), Expect = 1e-15
Identities = 87/304 (28%), Positives = 139/304 (45%), Gaps = 29/304 (9%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGVLLK 678
F +E SG + + L R + Y A N L + T+ V+D ND
Sbjct: 183 FQIEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITIDVLDENDNPPEFAP 242
Query: 679 GAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIAIA-ED 735
G H VKE S +G + + + G +R+ L+ + D T+ I E
Sbjct: 243 GPHHA---RVKERSPSGTKVADVIARDADDPQ-QPYGQIRYSLLPSPGDATNKFMIHHER 298
Query: 736 GTIFT-QKPLDREKRDVYRMTVIAEFNKGV-ISGAGIYQVTIYIEDENDNPPVFEHATYE 793
GT+ T LDRE+ Y + + A + +S + +TI + D ND+PPVF + Y+
Sbjct: 299 GTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYK 358
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVD--ENTGVVKFIG 850
+ E++KIG+EI + TDAD G NA +Y + G+ MF ++ +N GV+K +
Sbjct: 359 PIVAEDAKIGSEIVR---LSTTDADVGENAQSIYVIEDGDDSAMFSIEAIDNLGVLK-VK 414
Query: 851 DSLDREKKIMYKLS--LVARDT---------GGLSSEAELIIMIGDENDNKPEFNQIEEN 899
LD E +K S + AR+T G + +++I + D N+ PEF ++
Sbjct: 415 KRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNE-PPEFTEVNYE 473
Query: 900 SKVR 903
VR
Sbjct: 474 FSVR 477
Score = 72.9 bits (171), Expect = 6e-11
Identities = 113/460 (24%), Positives = 184/460 (40%), Gaps = 39/460 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQN--GMVLYDLQRT 502
+ + +LD NDN P F P + +K + GT + V A D D Q G + Y L +
Sbjct: 226 ITIDVLDENDNPPEFAPGP-HHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPS 284
Query: 503 SNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
T+ F I+ GTVS S + A + +P+ R A T+ ++
Sbjct: 285 PG-DATNKFMIHHERGTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVI 343
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVPFA 621
+ P P F+ PY+ V + IG+ + ++ DA +N S ++ ++ F+
Sbjct: 344 DVNDSP--PVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFS 401
Query: 622 VE--ERSGVITVVDDLSRYNRPMYDFEAVALQENA----NLSI------VTNATVHVVDV 669
+E + GV+ V L P + + N NL+ VT+ + V DV
Sbjct: 402 IEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDV 461
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
N+ + F V+E+ AI ++++ G FL +D +
Sbjct: 462 NEPP----EFTEVNYEFSVRED----AIRGFPIRAVTAVDPEGDSFSYFL----RDESKR 509
Query: 730 IAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP-VF 787
AI A G I LDRE + Y +TV A + G + +VTI I D NDNPP
Sbjct: 510 FAIDAVSGMISVAGELDRELQATYDVTVYAG-SPGDLDFRSTARVTISISDVNDNPPHPL 568
Query: 788 EHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA--LFMYTLFGEGKEMFD-VDENTG 844
+ T + + +N +I + IK TD D N Y+ + + F+ V+ + G
Sbjct: 569 DGDTVQVVLCDNQHEKGQI-LHPKIKFTDPDSPINGQPFTYYSTEHDNYKHFELVNNDDG 627
Query: 845 VVKFIGDSLDREKKIM-YKLSLVARDTGGLSSEAELIIMI 883
I Y+L ++ D G A I +
Sbjct: 628 TASLRTAHRGYSSSIREYELPVIVEDNGSPKLNATYTITV 667
Score = 69.3 bits (162), Expect = 8e-10
Identities = 85/327 (25%), Positives = 142/327 (43%), Gaps = 39/327 (11%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA----PIGP--SLTIPLTVPR 136
+T+ + D NDN P F P+H V E +P+G K + P P + L
Sbjct: 226 ITIDVLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSP 285
Query: 137 GLTIFKDIRAFDRDKPNTPNSDV-------HYSIVSGNDDGHFALESSHKPVLLLRKVLD 189
G K + +R +T S++ + ++ DD + L S L + V+D
Sbjct: 286 GDATNKFMIHHERGTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTI-SVID 344
Query: 190 YDAGDKEF----QLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS 245
+ F I+A +I EI+ + D D+G A Y + G+D +FS
Sbjct: 345 VNDSPPVFVNEPYKPIVAEDAKIGSEIV---RLSTTDADVGENAQSIYVIEDGDDSAMFS 401
Query: 246 LDSVN--GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ-------ARVEIEL 296
+++++ G L ++K LD + + + + ++V+A + A V I +
Sbjct: 402 IEAIDNLGVLKVKKRLDYETAPD---HKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITV 458
Query: 297 LDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDP 356
D+N+ PEF Y S+ E+ GF + V A D E F+Y L D F+ID
Sbjct: 459 TDVNEP-PEFTEVNYEFSVREDAIRGFPIRAVTAVDP---EGDSFSYFLRDESKRFAIDA 514
Query: 357 RSGWLTVRNQTVLDREAHSSLRMKVYA 383
SG ++V + LDRE ++ + VYA
Sbjct: 515 VSGMISVAGE--LDRELQATYDVTVYA 539
Score = 67.3 bits (157), Expect = 3e-09
Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 13/215 (6%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSADALEVKRYFVI 994
++ E+ IG+ I++L+ D D G N Q Y +S ++ + + L+VK+
Sbjct: 360 IVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIEAIDNLGVLKVKKRLDY 419
Query: 995 NERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
H R + N++ L G+++D V + V DVN+ P F + Y F+V
Sbjct: 420 ETAPDHKYSVRVRARNTHPDPNLAYL--GSMDDVTDVVITVTDVNEP-PEFTEVNYEFSV 476
Query: 1055 EEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETED 1114
E + V A D + + +YF++ D F I ++G++SV GELDRE +
Sbjct: 477 REDAIRGFPIRAVTAVDPE---GDSFSYFLR--DESKRFAIDAVSGMISVAGELDRELQA 531
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
Y +TV A G DVNDN P
Sbjct: 532 TYDVTVYAGSPG-DLDFRSTARVTISISDVNDNPP 565
Score = 60.1 bits (139), Expect = 5e-07
Identities = 47/163 (28%), Positives = 80/163 (49%), Gaps = 14/163 (8%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN-PLKTA 288
T+ Y + LF ++ ++G LFL+++LD + + +++ L V A N PL+ A
Sbjct: 169 TVIYSISGRGADSLFQIEPLSGHLFLKQKLDREMQ-----SSYKLNVSAHDGNGVPLEPA 223
Query: 289 QARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD--QGENGEFTYQL- 345
+ + I++LD NDN PEF ++ + E P+G V V+A D D Q G+ Y L
Sbjct: 224 -SEITIDVLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLL 282
Query: 346 ---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D F I G ++ LDRE ++ + + A++
Sbjct: 283 PSPGDATNKFMIHHERGTVSTITSN-LDREESATYELVIQARD 324
Score = 58.8 bits (136), Expect = 1e-06
Identities = 91/369 (24%), Positives = 146/369 (39%), Gaps = 37/369 (10%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKK 1047
F I GH+ + + L E S ++LN+SA DG L + + V D ND+ P F
Sbjct: 183 FQIEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITIDVLDENDNPPEFAP 242
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQN--ANLTYFIQPSDTDLP--FEISPLTGVLS 1103
++ V+E + + V A DAD Q + Y + PS D F I G +S
Sbjct: 243 GPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHHERGTVS 302
Query: 1104 -VNGELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ LDRE Y L + ARD+ DVND+ P F + E
Sbjct: 303 TITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVF-----VNEPY 357
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPI------GTTVAKVFANDTDFIG---NGNG 1212
P E + E ++ + A + ENA G A D +G
Sbjct: 358 KPIVAEDAKIGSE-IVRLSTTDADVGENAQSIYVIEDGDDSAMFSIEAIDNLGVLKVKKR 416
Query: 1213 LILYSLPQRKNQQNLGLPSLSSTAIL--MVTVADVPDEV----EMSDKPVFISRYYELEI 1266
L + P K + + L + ++ DV D V ++++ P F YE +
Sbjct: 417 LDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNEPPEFTEVNYEFSV 476
Query: 1267 EENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
E+ + ++ + E Y++ +E+ + F ID +G + + DRE++
Sbjct: 477 REDAIRGFPIRAVTAVDP-EGDSFSYFLRDES-----KRFAIDAVSGMISVAGELDRELQ 530
Query: 1327 DTYEVIVRA 1335
TY+V V A
Sbjct: 531 ATYDVTVYA 539
Score = 58.0 bits (134), Expect = 2e-06
Identities = 62/197 (31%), Positives = 85/197 (43%), Gaps = 22/197 (11%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLN--GQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ E P GT + + A D D GQIRY + PS DA ++ + +ER
Sbjct: 249 VKERSPSGTKVADVIARDADDPQQPYGQIRYS------LLPSP--GDA--TNKFMIHHER 298
Query: 998 HGHVIVARSLPPESE--FRLNISALDGGNLNDNIS----VRVFVKDVNDHFPVFKKTWYN 1051
+ +L E + L I A D N + S + + V DVND PVF Y
Sbjct: 299 GTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYK 358
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPL--TGVLSVNGELD 1109
V E + ++ TDAD G+NA Y I+ D F I + GVL V LD
Sbjct: 359 PIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIEAIDNLGVLKVKKRLD 418
Query: 1110 RET--EDKYILTVVARD 1124
ET + KY + V AR+
Sbjct: 419 YETAPDHKYSVRVRARN 435
Score = 50.8 bits (116), Expect = 3e-04
Identities = 37/156 (23%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 752 YRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI 811
+ + ++++ + + G+Y+ + + + V F NS +E + D +
Sbjct: 99 FNLKMLSQKHNNIYRVDGLYKRIVALRSGSKKSKVLSRQKRWEF---NSYSVSENREDQL 155
Query: 812 I-KATDADEGTNALFMYTLFGEGKE-MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
I + + + +Y++ G G + +F ++ +G + F+ LDRE + YKL++ A D
Sbjct: 156 IARLRSSYDNYTGTVIYSISGRGADSLFQIEPLSGHL-FLKQKLDREMQSSYKLNVSAHD 214
Query: 870 TGGLSSE--AELIIMIGDENDNKPEFNQIEENSKVR 903
G+ E +E+ I + DENDN PEF +++V+
Sbjct: 215 GNGVPLEPASEITIDVLDENDNPPEFAPGPHHARVK 250
Score = 47.2 bits (107), Expect = 0.003
Identities = 75/286 (26%), Positives = 124/286 (43%), Gaps = 30/286 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDE----------LTPT----GEKA-FIFLIA 122
SA ++T+ + DVND+ P+F++ PY V E L+ T GE A I++I
Sbjct: 333 SATTTLTISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIE 392
Query: 123 PIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVL 182
S + L + K + D + V + + D + A S V
Sbjct: 393 DGDDSAMFSIEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVT 452
Query: 183 -LLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDR 241
++ V D + EF V R ++ + PI A+ G + Y L ++
Sbjct: 453 DVVITVTDVNE-PPEFTEVNYEFSVR--EDAIRGFPIRAVTAVDPEGDSFSYFL--RDES 507
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
K F++D+V+G + + ELD + LQA T+ + V A + + ARV I + D+ND
Sbjct: 508 KRFAIDAVSGMISVAGELDRE----LQA-TYDVTVYAGSPGDLDFRSTARVTISISDVND 562
Query: 302 NLPE-FEVDFYNISIVENLPNGFSVL--QVMATDKDQGENGE-FTY 343
N P + D + + +N +L ++ TD D NG+ FTY
Sbjct: 563 NPPHPLDGDTVQVVLCDNQHEKGQILHPKIKFTDPDSPINGQPFTY 608
Score = 46.8 bits (106), Expect = 0.005
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 12/166 (7%)
Query: 231 LRYELIS--GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT- 287
+RY L+ G+ F + G++ +LD E ++ T+ L +QA N +
Sbjct: 277 IRYSLLPSPGDATNKFMIHHERGTVSTITS-NLDRE---ESATYELVIQARDDPNARLSF 332
Query: 288 -AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
A + I ++D+ND+ P F + Y + E+ G ++++ TD D GEN + Y ++
Sbjct: 333 SATTTLTISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIE 392
Query: 347 --DPKGAFSID--PRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D FSI+ G L V+ + + ++V A+ T+P
Sbjct: 393 DGDDSAMFSIEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHP 438
Score = 40.7 bits (91), Expect = 0.30
Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 1082 YFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
Y I D F+I PL+G L + +LDRE + Y L V A D G
Sbjct: 172 YSISGRGADSLFQIEPLSGHLFLKQKLDREMQSSYKLNVSAHD-GNGVPLEPASEITIDV 230
Query: 1142 XDVNDNSPKF 1151
D NDN P+F
Sbjct: 231 LDENDNPPEF 240
Score = 40.3 bits (90), Expect = 0.40
Identities = 46/167 (27%), Positives = 78/167 (46%), Gaps = 18/167 (10%)
Query: 1220 QRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSL 1279
Q ++ N L S S+T L ++V DV D PVF++ Y+ + E+ E+V L
Sbjct: 321 QARDDPNARL-SFSATTTLTISVIDVNDS-----PPVFVNEPYKPIVAEDAKIGSEIVRL 374
Query: 1280 NLTEH--YENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAER 1337
+ T+ EN + Y I + +D+ + ID G L + + D E ++ VR R
Sbjct: 375 STTDADVGENAQSIYVIEDGDDSAMFSIEAID-NLGVLKVKKRLDYETAPDHKYSVRV-R 432
Query: 1338 QKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGN 1384
+ + P++ Y + D + VV+ + DVN+ P+FT N
Sbjct: 433 ARNTHPDPNLAYLGSMDDV-------TDVVITVTDVNE-PPEFTEVN 471
>UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13;
Euteleostomi|Rep: CDNA FLJ25193 fis, clone JTH00761 -
Homo sapiens (Human)
Length = 493
Score = 88.6 bits (210), Expect = 1e-15
Identities = 62/214 (28%), Positives = 95/214 (44%), Gaps = 7/214 (3%)
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
F V E AG + + S G G ++L+ + T + G I K LD
Sbjct: 51 FFVIEEYAGPE--PVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLD 108
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE++ Y + A + I ++D NDNPP+F Y + E S +GT
Sbjct: 109 REEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTS 168
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ A D G +A +YT+ +G F VD TGVV+ ++DRE + + + +
Sbjct: 169 VIQVTAHDADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVI 227
Query: 866 VARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
A+D GGLS + + + D NDN P+F Q
Sbjct: 228 QAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQ 261
Score = 81.4 bits (192), Expect = 2e-13
Identities = 61/217 (28%), Positives = 98/217 (45%), Gaps = 6/217 (2%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V VTL D NDN P F P +LY+FS+ A GT++G+++A DPDLG N ++ Y
Sbjct: 239 LSGSTTVTVTLSDVNDNPPKF-PQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYS 297
Query: 499 -LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
L + + + G ++V + E + ++ VEA++ +P+ R
Sbjct: 298 ILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG-PFK 356
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGY 614
+ R + P+ P F A Y V N GT VGQI D + + Y +L
Sbjct: 357 DVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHS 416
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
+ F+++ G I L R R ++ +A +
Sbjct: 417 DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATE 453
Score = 79.8 bits (188), Expect = 5e-13
Identities = 73/271 (26%), Positives = 124/271 (45%), Gaps = 19/271 (7%)
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVV 667
LL G G F ++E +G I V L R + Y A A+ +N L + + V
Sbjct: 82 LLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQ 141
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF-HTNMSSIYGNGTGNVRFLIANQQDV 726
D+ND + G + + + ++ G ++ Q+ H YGN V ++
Sbjct: 142 DINDNPPIFPLGPYHATVPEM--SNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFF 199
Query: 727 TDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNP 784
+ D + G + T P +DRE ++ + + + A+ G + G +G VT+ + D NDNP
Sbjct: 200 SVD---PQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNP 256
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMF----DV 839
P F + Y+ ++E + GT + ++A D D G NAL Y++ GEG E F D+
Sbjct: 257 PKFPQSLYQFSVVETAGPGTLV---GRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDL 313
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
G++ + LD E + Y + A +T
Sbjct: 314 QGRDGLLT-VRKPLDFESQRSYSFRVEATNT 343
Score = 74.9 bits (176), Expect = 2e-11
Identities = 96/373 (25%), Positives = 162/373 (43%), Gaps = 42/373 (11%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
FVI+E G++ V +SL E +++ L A+D + L + V+D+ND+ P+F
Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLP-FEISPLTGVL 1102
Y+ V E + +V A DAD +G +A L Y + LP F + P TGV+
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDG---LPFFSVDPQTGVV 208
Query: 1103 -SVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
+ +DRET++++++ + A+D G DVNDN PKF L ++
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFP--QSLYQF 266
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV-----AKVFANDTDFIGNGNGLIL 1215
E V + + +NA + ++ ++ F+ TD G +GL+
Sbjct: 267 SVVETAGPGT----LVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGR-DGLLT 321
Query: 1216 YSLP-QRKNQQNLGLPSLSSTAIL---------MVTVADVPDEV-EMSDKPVFISRYYEL 1264
P ++Q++ ++ ++ VA V V + + P F Y L
Sbjct: 322 VRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHL 381
Query: 1265 EIEENVNAPVELVSLNLTEHYEN--FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+ EN AP LV ++ +RY IL +D + R F I P GT++ D
Sbjct: 382 TVPEN-KAPGTLVGQISAADLDSPASPIRYSILPHSDPE--RCFSIQPEEGTIHTAAPLD 438
Query: 1323 REVKDTYEVIVRA 1335
RE + + + V A
Sbjct: 439 REARAWHNLTVLA 451
Score = 70.5 bits (165), Expect = 3e-10
Identities = 88/332 (26%), Positives = 141/332 (42%), Gaps = 38/332 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P+F P Y ++ + VGT + +V A D P G + ++Y +
Sbjct: 138 IKVQDINDNPPIF-PLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTV---- 192
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F ++P TG V A + + + ++A D + S T+ VT
Sbjct: 193 -LDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGS---TTVTVT 248
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV 618
+ P P F + Y+F V G GT VG++R D ++ ++Y +L G E
Sbjct: 249 LSDVNDNP--PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG-EGSE 305
Query: 619 PFAV----EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F++ + R G++TV L ++ Y F A + + + DV R
Sbjct: 306 AFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFK--DVASVRV 363
Query: 675 VLLKGAHSPII----FH--VKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ P +H V EN A G +GQI ++ S +R+ I D
Sbjct: 364 AVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDS----PASPIRYSILPHSDPE 419
Query: 728 DDIAIA-EDGTIFTQKPLDREKRDVYRMTVIA 758
+I E+GTI T PLDRE R + +TV+A
Sbjct: 420 RCFSIQPEEGTIHTAAPLDREARAWHNLTVLA 451
Score = 67.3 bits (157), Expect = 3e-09
Identities = 85/322 (26%), Positives = 124/322 (38%), Gaps = 27/322 (8%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPSLTIPLTVPRGLT 139
+ ++D+NDN PIF PYH TV E++ G G S + TV GL
Sbjct: 138 IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP 197
Query: 140 IFKDIRAFDRDKPNTPNSDVHYS-----IVSGND-DGHFALESSHKPVLLLRKVLDYDAG 193
F + PN D ++ D GH S V + ++ D
Sbjct: 198 FFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVN-DNP 256
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS----LDSV 249
K Q + S + A D DLG A + Y ++ G + FS L
Sbjct: 257 PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGR 316
Query: 250 NGSLFLEKELDLDAEHNLQAN---TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+G L + K LD +++ + T L A P K A V + + D + P F
Sbjct: 317 DGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV-ASVRVAVQDAPEP-PAF 374
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTV 363
Y++++ EN G V Q+ A D D + Y + DP+ FSI P G T+
Sbjct: 375 TQAAYHLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHSDPERCFSIQPEEG--TI 431
Query: 364 RNQTVLDREAHSSLRMKVYAKE 385
LDREA + + V A E
Sbjct: 432 HTAAPLDREARAWHNLTVLATE 453
Score = 63.3 bits (147), Expect = 5e-08
Identities = 62/201 (30%), Positives = 95/201 (47%), Gaps = 24/201 (11%)
Query: 934 LGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYF 992
LGP +PE +GT++I++ A D D G NS +KL L+ +F
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYG------NS------AKLVYTVLDGLPFF 199
Query: 993 VINERHGHVIVA---RSLPPESEFRLNISALD-GGN---LNDNISVRVFVKDVNDHFPVF 1045
++ + G V A + EF + I A D GG+ L+ + +V V + DVND+ P F
Sbjct: 200 SVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKF 259
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP----LTGV 1101
++ Y F+V E ++G++ A D D G NA + Y I + F IS G+
Sbjct: 260 PQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGL 319
Query: 1102 LSVNGELDRETEDKYILTVVA 1122
L+V LD E++ Y V A
Sbjct: 320 LTVRKPLDFESQRSYSFRVEA 340
Score = 62.5 bits (145), Expect = 9e-08
Identities = 57/186 (30%), Positives = 88/186 (47%), Gaps = 19/186 (10%)
Query: 210 KEILFPEPI-----HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAE 264
+E PEP+ H+ D D G G T +Y L +F +D G++ + K LD E
Sbjct: 55 EEYAGPEPVLIGKLHS-DVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLD--RE 110
Query: 265 HNLQANTFVLQVQASQL--NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG 322
Q +VL QA N PL+ + I++ D+NDN P F + Y+ ++ E G
Sbjct: 111 EKAQ---YVLLAQAVDRASNRPLEPPSEFI-IKVQDINDNPPIFPLGPYHATVPEMSNVG 166
Query: 323 FSVLQVMATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
SV+QV A D D G + + Y + D FS+DP++G + +DRE +
Sbjct: 167 TSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPN-MDRETQEEFLV 225
Query: 380 KVYAKE 385
+ AK+
Sbjct: 226 VIQAKD 231
Score = 62.1 bits (144), Expect = 1e-07
Identities = 96/412 (23%), Positives = 173/412 (41%), Gaps = 38/412 (9%)
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALF 535
+IGK+ + D D G+ G Y L T+ F I+ TG + V +S E ++ L
Sbjct: 64 LIGKLHS-DVDRGE-GRTKYLLTGEGAGTV---FVIDEATGNIHVTKSLDREEKAQYVLL 118
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
+A D+ +N S ++ ++ N P P +G PY V +GTSV Q+
Sbjct: 119 AQAVDRASNRPLEPPSEFIIKVQ---DINDNPPIFP--LG-PYHATVPEMSNVGTSVIQV 172
Query: 596 RVNDAFEQN-DVSYDLLHGYEEGVPF-AVEERSGVI-TVVDDLSRYNRPMYDFEAVALQE 652
+DA + + S L++ +G+PF +V+ ++GV+ T + ++ R + + A
Sbjct: 173 TAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDM 232
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGN 711
++ ++ +T V ++D K S F V E + G +G++ + N
Sbjct: 233 GGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRL-RAQDPDLGDN 291
Query: 712 GTGNVRFLIANQQD---VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
L + ++ D+ DG + +KPLD E + Y V E +I A
Sbjct: 292 ALMAYSILDGEGSEAFSISTDLQ-GRDGLLTVRKPLDFESQRSYSFRV--EATNTLIDPA 348
Query: 769 --------GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ V + ++D + PP F A Y + EN GT + I A D D
Sbjct: 349 YLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQ---ISAADLDSP 404
Query: 821 TNAL-FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+ + + + + F + G + LDRE + + L+++A + G
Sbjct: 405 ASPIRYSILPHSDPERCFSIQPEEGTI-HTAAPLDREARAWHNLTVLATELG 455
Score = 58.8 bits (136), Expect = 1e-06
Identities = 55/175 (31%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y ++ G FS+D G + ++D E + F++ +QA
Sbjct: 177 ADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIP-NMDRETQEE---FLVVIQAK 230
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + + V + L D+NDN P+F Y S+VE G V ++ A D D G+
Sbjct: 231 DMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGD 290
Query: 338 NGEFTYQLDDPKG--AFSIDP----RSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N Y + D +G AFSI R G LTVR LD E+ S +V A T
Sbjct: 291 NALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP--LDFESQRSYSFRVEATNT 343
Score = 50.4 bits (115), Expect = 4e-04
Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 13/196 (6%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSA--DALEVKRY 991
F + E GT + +L A D D G N + Y SE + + L L V++
Sbjct: 266 FSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ + + + ++ + L G D SVRV V+D + P F + Y+
Sbjct: 326 LDFESQRSYSFRVEA----TNTLIDPAYLRRGPFKDVASVRVAVQDAPEP-PAFTQAAYH 380
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISPLTGVLSVNGELDR 1110
V E + ++G++ A D D + + Y I P SD + F I P G + LDR
Sbjct: 381 LTVPENKAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDR 439
Query: 1111 ETEDKYILTVVARDNG 1126
E + LTV+A + G
Sbjct: 440 EARAWHNLTVLATELG 455
Score = 39.5 bits (88), Expect = 0.69
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 21/126 (16%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
FVID G +++ +S DRE K Y ++ +A + +R L P +E
Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLE----PPSE------------ 135
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPT---ASRTVRADT 1422
+++++D+NDN P F G P +P + G V+Q+ P+ +++ V
Sbjct: 136 FIIKVQDINDNPPIFPLG--PYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVL 193
Query: 1423 DELVFF 1428
D L FF
Sbjct: 194 DGLPFF 199
Score = 37.5 bits (83), Expect = 2.8
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 3/101 (2%)
Query: 1052 FNVEEAQYTRRVL-GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F +EE VL GK+ + D D G+ Y + F I TG + V LDR
Sbjct: 52 FVIEEYAGPEPVLIGKLHS-DVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLDR 109
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E + +Y+L A D D+NDN P F
Sbjct: 110 EEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIF 150
>UniRef50_Q5TAN1 Cluster: Protocadherin 8; n=14; Tetrapoda|Rep:
Protocadherin 8 - Homo sapiens (Human)
Length = 973
Score = 88.6 bits (210), Expect = 1e-15
Identities = 143/596 (23%), Positives = 237/596 (39%), Gaps = 66/596 (11%)
Query: 589 GTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAVEERSGVITVVD---DLSRY--NRP- 641
GT +G + + + D S+ L+ + + V E G +TV D D R P
Sbjct: 43 GTVIGTLAEDLHMKVSGDTSFRLMKQFNSSL-LRVREGDGQLTVGDAGLDRERLCGQAPQ 101
Query: 642 -MYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
+ F+ V+ QE L + V V DVND + A P+ E S GAA+G
Sbjct: 102 CVLAFDVVSFSQEQFRL---VHVEVEVRDVNDHAPRFPR-AQIPV-----EVSEGAAVGT 152
Query: 700 IFHTNM---SSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT----IFTQKPLDREKRDVY 752
+ + NG VR L ++ DG + + LDRE + Y
Sbjct: 153 RIPLEVPVDEDVGANGLQTVR-LAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAY 211
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-EHATYEGFIMENSKIGTEIKMDNI 811
+ ++A+ + G + +++ + D ND+ P F + A E + E++ +G+ + +D
Sbjct: 212 SLELVAQ-DGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGS-LLLD-- 267
Query: 812 IKATDADEGTNALFMYTLFG-----EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ A D DEG N ++ FG E + +F +D +G + G +D E++ Y+L +
Sbjct: 268 LDAADPDEGPNGDVVFA-FGARTPPEARRLFRLDPRSGRLTLAGP-VDYERQDTYELDVR 325
Query: 867 ARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK 924
A+D G ++ ++I+ I D NDN P+ + A +
Sbjct: 326 AQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADAS 385
Query: 925 NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
+ + G L+PE + + ++ D DSG NGQ+R + A
Sbjct: 386 SPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAG 445
Query: 985 ALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVND 1040
+ Y V+ A SL E +E+ L + A D G L V V D ND
Sbjct: 446 S-----YLVVT--------AASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDEND 492
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-------TDLPF 1093
+ P+F + Y +V E L V A D D G+N +TY + ++
Sbjct: 493 NAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYV 552
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ P TG + D ET + + + A D G D ND++P
Sbjct: 553 SVDPATGAIYALRSFDYETLRQLDVRIQASDGG-SPQLSSSALVQVRVLDQNDHAP 607
Score = 68.5 bits (160), Expect = 1e-09
Identities = 83/271 (30%), Positives = 113/271 (41%), Gaps = 37/271 (13%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFIS-RYYELEIEENVNAPVELVSLNLTE 1283
Q+ G P S+TA L V V D D P F E+E+ E+ L+ L+ +
Sbjct: 218 QDGGRPPRSATAALSVRVLDANDH-----SPAFPQGAVAEVELAEDAPVGSLLLDLDAAD 272
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
E N + + + RR F +DPR+G L L D E +DTYE+ VRA+
Sbjct: 273 PDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQ----- 327
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVT-AIPTTAPF--G 1398
D G KV+VRI+DVNDN+P PL P T+PF
Sbjct: 328 ------------DRGPGPRAATCKVIVRIRDVNDNAPDI--AITPLAAPGAPATSPFAAA 373
Query: 1399 YQVMQLKGAIGHHPTASRTVRADTDELV--FFERLSLNGLTSPQATDSDIGINADIRYQI 1456
L GA P + T A LV R SL L S +D D G N +R +
Sbjct: 374 AAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVS--TSDRDSGANGQVRCAL 431
Query: 1457 LNEQAPRFAIDPV-SGTVRVVAALARDAGRV 1486
+ F + P +G+ VV A + D R+
Sbjct: 432 YGHE--HFRLQPAYAGSYLVVTAASLDRERI 460
Score = 66.1 bits (154), Expect = 7e-09
Identities = 111/454 (24%), Positives = 179/454 (39%), Gaps = 50/454 (11%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
R+LF LD +G L L +D + + +T+ L V+A + A +V + + D+N
Sbjct: 294 RRLFRLDPRSGRLTLAGPVDYERQ-----DTYELDVRAQDRGPGPRAATCKVIVRIRDVN 348
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK-GAFSIDP--- 356
DN P+ + P A G + P+ GA S+ P
Sbjct: 349 DNAPDIAI---TPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGA 405
Query: 357 -RSGWLTVRNQTVLDREAHSSLRMKVYAKE---TNPSVVGTFADSQRIAKWRRQPLETNA 412
R + + + + D A+ +R +Y E P+ G++ + R + E N
Sbjct: 406 ARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNL 465
Query: 413 PLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN 472
T V D+ + Y V + D NDN P+F +YE S++ N
Sbjct: 466 -----TLVAEDRGAPPLRTVRPYT----------VRVGDENDNAPLFTRP-VYEVSVREN 509
Query: 473 AKVGTVIGKVKAVDPDLGQNGMVLYDLQRT----SNLTITSPFKINPNTGTVSVAESPIL 528
G + V A D DLG+NG V Y L + +++ ++P TG + S
Sbjct: 510 NPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDY 569
Query: 529 EGRHALFV--EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI--PDFMGAPYEFWVGS 584
E L V +ASD S + S A+V + V + P + P E V
Sbjct: 570 ETLRQLDVRIQASD---GGSPQLSSSALVQVRVL-DQNDHAPVLVHPAPANGSLEVAVPG 625
Query: 585 NVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
T V +++ DA E +++++ L E FA+ R+G I + DLS+ P
Sbjct: 626 RTAKDTVVARVQARDADEGANGELAFE-LQQQEPREAFAIGRRTGEILLTGDLSQ-EPPG 683
Query: 643 YDFEA-VALQENANLSIVTNATV-HVVDVNDERG 674
F A + + + + T ATV VV RG
Sbjct: 684 RVFRALLVISDGGRPPLTTTATVSFVVTAGGGRG 717
Score = 62.9 bits (146), Expect = 7e-08
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 15/196 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G + + A D D G NGQ+ Y + +++ V Y ++ G
Sbjct: 506 VRENNPPGAYLATVAARDRDLGRNGQVTYR------LLEAEVGRAGGAVSTYVSVDPATG 559
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVF-KKTWYNFNV 1054
+ RS E+ + + I A DGG+ L+ + V+V V D NDH PV N ++
Sbjct: 560 AIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSL 619
Query: 1055 EEAQYTRR----VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
E A R V+ +V A DAD G N L + +Q + F I TG + + G+L +
Sbjct: 620 EVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQ 679
Query: 1111 ETEDKYILTVVARDNG 1126
E + ++ +G
Sbjct: 680 EPPGRVFRALLVISDG 695
Score = 58.0 bits (134), Expect = 2e-06
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 221 IDQDLGVGATLRYELISGNDRKLFSLDS-VNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
+D+D+G L + L + +G+ + L + + QA + L++ A
Sbjct: 160 VDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQA-AYSLELVAQ 218
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P ++A A + + +LD ND+ P F + + + E+ P G +L + A D D+G N
Sbjct: 219 DGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPN 278
Query: 339 GE--FTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
G+ F + P A F +DPRSG LT+ +D E + + V A++ P
Sbjct: 279 GDVVFAFGARTPPEARRLFRLDPRSGRLTLAGP--VDYERQDTYELDVRAQDRGP 331
Score = 56.4 bits (130), Expect = 6e-06
Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LDAND++P F + E + +A VG+++ + A DPD G NG V++ +
Sbjct: 231 LSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTP 290
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F+++P +G +++A E + ++ Q P R + V+ + + R
Sbjct: 291 PEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVI-VRI-RDVN 348
Query: 565 GNKPDI 570
N PDI
Sbjct: 349 DNAPDI 354
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN-TFVLQVQASQ 280
D+D G +R L +L + GS + LD E + N T V + + +
Sbjct: 418 DRDSGANGQVRCALYGHEHFRL--QPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAP 475
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
PL+T + + + D NDN P F Y +S+ EN P G + V A D+D G NG+
Sbjct: 476 ---PLRTVRPYT-VRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQ 531
Query: 341 FTYQL 345
TY+L
Sbjct: 532 VTYRL 536
Score = 51.6 bits (118), Expect = 2e-04
Identities = 40/156 (25%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 218 IHAIDQDLGVGATLRYELIS-------GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
+ A D+DLG + Y L+ G S+D G+++ + D + L
Sbjct: 519 VAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLD-- 576
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSV 325
+++QAS +P ++ A V++ +LD ND+ P +++ V
Sbjct: 577 ---VRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVV 633
Query: 326 LQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
+V A D D+G NGE ++L +P+ AF+I R+G
Sbjct: 634 ARVQARDADEGANGELAFELQQQEPREAFAIGRRTG 669
Score = 47.6 bits (108), Expect = 0.003
Identities = 54/166 (32%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFV---PSN-LYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
QL S V+V +LD ND+ PV V P+N E ++ TV+ +V+A D D G NG
Sbjct: 588 QLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANG 647
Query: 494 MVLYDLQRTSNLTITSPFKINPNTG----TVSVAESPILEGRHALFVEASDQPANPSERR 549
+ ++LQ+ F I TG T +++ P AL V SD P
Sbjct: 648 ELAFELQQQEP---REAFAIGRRTGEILLTGDLSQEPPGRVFRALLV-ISDGGRPPLT-- 701
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW-VGSNVGIGTSVGQ 594
+ A V+ VT G G P P G+P GS +G+ SV Q
Sbjct: 702 -TTATVSFVVTAG-GGRGPAAPASAGSPERSRPPGSRLGVSGSVLQ 745
Score = 45.6 bits (103), Expect = 0.011
Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 10/130 (7%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ V V V+DVNDH P F + V E + D D G N T ++ ++
Sbjct: 119 VHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQT--VRLAE 176
Query: 1089 TDLPFEISPLTGV-------LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
PF + T L + ELDRE++ Y L +VA+D G
Sbjct: 177 PHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGG-RPPRSATAALSVRV 235
Query: 1142 XDVNDNSPKF 1151
D ND+SP F
Sbjct: 236 LDANDHSPAF 245
Score = 44.8 bits (101), Expect = 0.018
Identities = 64/271 (23%), Positives = 102/271 (37%), Gaps = 15/271 (5%)
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDV 669
L+G+E S ++ L R Y+ VA A L V TV V D
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDE 490
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND + + + V+EN+ A + NG R L A
Sbjct: 491 NDNAPLFTRPVYE---VSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGA 547
Query: 730 IA--IAED---GTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
++ ++ D G I+ + D E R + ++ +S + + QV + D+ND+
Sbjct: 548 VSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVL--DQNDH 605
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNI--IKATDADEGTNALFMYTLFG-EGKEMFDVD 840
PV H +E + G K + ++A DADEG N + L E +E F +
Sbjct: 606 APVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIG 665
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
TG + GD +++ LV D G
Sbjct: 666 RRTGEILLTGDLSQEPPGRVFRALLVISDGG 696
Score = 40.7 bits (91), Expect = 0.30
Identities = 68/291 (23%), Positives = 112/291 (38%), Gaps = 21/291 (7%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+ ++ V+VEV + D ND+ P F P + A VGT I VD D+G NG
Sbjct: 111 FSQEQFRLVHVEVEVRDVNDHAPRF-PRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANG- 168
Query: 495 VLYDLQRTSNLTITSPFKINPNTGT--VSVAESPILE--GRHALFVEASDQPANPSER-- 548
LQ SPF++ T A+ +L+ R + + + A R
Sbjct: 169 ----LQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPP 224
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
R + A +++ V + P P GA E + + +G+ + + D E DV
Sbjct: 225 RSATAALSVRVL-DANDHSPAFP--QGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDV 281
Query: 607 --SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NAT 663
++ E F ++ RSG +T+ + + Y+ + A T
Sbjct: 282 VFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVI 341
Query: 664 VHVVDVNDER-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
V + DVND + + +P +A AA + + SS G GT
Sbjct: 342 VRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGT 392
Score = 39.1 bits (87), Expect = 0.92
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
VE+E+ D+ND+ P F + + E G + + D+D G NG T +L +P
Sbjct: 121 VEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSP 180
Query: 352 FSID--PRSGWLTVRNQTV---LDREAHSSLRMKVYAKE-TNPSVVGTFADSQRI 400
F ++ R+ + + LDRE+ ++ +++ A++ P T A S R+
Sbjct: 181 FRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRV 235
>UniRef50_Q32P55 Cluster: CDH23 protein; n=1; Homo sapiens|Rep:
CDH23 protein - Homo sapiens (Human)
Length = 445
Score = 88.6 bits (210), Expect = 1e-15
Identities = 98/332 (29%), Positives = 148/332 (44%), Gaps = 55/332 (16%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFK 142
V + + DVNDN P F + PY S+ IP P G IF
Sbjct: 59 VNIQVGDVNDNAPTFHNQPY------------------------SVRIPENTPVGTPIFI 94
Query: 143 DIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQL--- 199
+ A D D V YS + FA++S+ V ++R+ LDY+ + +QL
Sbjct: 95 -VNATDPDLG--AGGSVLYSFQPPSQ--FFAIDSARGIVTVIRE-LDYET-TQAYQLTVN 147
Query: 200 --VIMASGKRIHKEILFPEP-------IHAIDQDLGVGATLRYELISGNDRKLFSLDSVN 250
+I+ I P I AIDQD G + Y ++SGN +F+LD ++
Sbjct: 148 AIIIIIINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYIS 207
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV----EIELLDLNDNLPEF 306
G L L LD E+ L ++ F+L V+ ++LN+ + A V I ++D+NDN PEF
Sbjct: 208 GVLTLNGL--LDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEF 265
Query: 307 EVDFYNISIVENLPNGFSV-LQVMATDKDQGENGEF-TYQLDDPKGAFSIDPRS----GW 360
Y+++I E GF++ L + DKD+G N F Y + + F I P S
Sbjct: 266 NSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKAD 325
Query: 361 LTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
+ +R LD E ++A E+ P VG
Sbjct: 326 IRIRVAIPLDYETVDRYDFDLFANESVPDHVG 357
Score = 71.7 bits (168), Expect = 1e-10
Identities = 106/420 (25%), Positives = 161/420 (38%), Gaps = 70/420 (16%)
Query: 403 WRRQPLETNAPLEKTT-YVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVP 461
W RQPL+ E T + D G T VN++V D NDN P F
Sbjct: 29 WLRQPLDRETKSEFTVEFSVSDHQGVITRK-----------VNIQVG--DVNDNAPTF-H 74
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS 521
+ Y + N VGT I V A DPDLG G VLY Q S F I+ G V+
Sbjct: 75 NQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF-----FAIDSARGIVT 129
Query: 522 VAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW 581
V E A + + ++ ++ I + T + P
Sbjct: 130 VIRELDYETTQAYQLTVN-----------AIIIIIINLPYSTNIYEHSPP---------- 168
Query: 582 VGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRP 641
G+ V I T++ Q D + Y ++ G + FA++ SGV+T+ L R N P
Sbjct: 169 -GTTVRIITAIDQ----DKGRPRGIGYTIVSGNTNSI-FALDYISGVLTLNGLLDREN-P 221
Query: 642 MYDFEAVALQENANLS---------IVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS 692
+Y + + L+ + T + V+D+ND +S I + +
Sbjct: 222 LYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVG 281
Query: 693 AGAAIG-QIFH-----TNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDR 746
+ Q+ +M +Y G + F+I+ + D I PLD
Sbjct: 282 FALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIIS-----PTSVQGKADIRIRVAIPLDY 336
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
E D Y + A N+ V G +V I + +ENDN P+F Y + EN +GT +
Sbjct: 337 ETVDRYDFDLFA--NESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSV 394
Score = 65.3 bits (152), Expect = 1e-08
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 9/134 (6%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
+ G ++ ++PLDRE + + + ++GVI+ +V I + D NDN P F + Y
Sbjct: 24 DTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITR----KVNIQVGDVNDNAPTFHNQPYS 79
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSL 853
I EN+ +GT I I+ ATD D G +Y+ F + F +D G+V I + L
Sbjct: 80 VRIPENTPVGTPI---FIVNATDPDLGAGGSVLYS-FQPPSQFFAIDSARGIVTVIRE-L 134
Query: 854 DREKKIMYKLSLVA 867
D E Y+L++ A
Sbjct: 135 DYETTQAYQLTVNA 148
Score = 61.3 bits (142), Expect = 2e-07
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 11/149 (7%)
Query: 236 ISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEI 294
+SG + + F+++ G ++L + LD + + + F ++ S + +V I
Sbjct: 10 VSGEEASRFFAVEPDTGVVWLRQPLDRETK-----SEFTVEFSVSDHQGVITR---KVNI 61
Query: 295 ELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
++ D+NDN P F Y++ I EN P G + V ATD D G G Y P F+I
Sbjct: 62 QVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAI 121
Query: 355 DPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
D G +TV + LD E + ++ V A
Sbjct: 122 DSARGIVTVIRE--LDYETTQAYQLTVNA 148
Score = 60.9 bits (141), Expect = 3e-07
Identities = 60/218 (27%), Positives = 91/218 (41%), Gaps = 40/218 (18%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
IPEN P+GT I +NA D D G G + Y F PPS+ +F I+ G
Sbjct: 82 IPENTPVGTPIFIVNATDPDLGAGGSVLYSFQ-----PPSQ----------FFAIDSARG 126
Query: 1000 HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
V V R L E+ ++ N + + + + P Y+ N+ E
Sbjct: 127 IVTVIRELDYETTQAYQLTV--------NAIIIIII-----NLP------YSTNIYEHSP 167
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET---EDKY 1116
+ + A D D G+ + Y I +T+ F + ++GVL++NG LDRE +
Sbjct: 168 PGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGF 227
Query: 1117 ILTVVA---RDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
ILTV D+ D+NDN+P+F
Sbjct: 228 ILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEF 265
Score = 59.3 bits (137), Expect = 8e-07
Identities = 45/138 (32%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Query: 987 EVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGNLNDNISVRVFVKDVNDHFPV 1044
E R+F + G V + + L E SEF + S D + V + V DVND+ P
Sbjct: 14 EASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITR-KVNIQVGDVNDNAPT 72
Query: 1045 FKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
F Y+ + E + V+ATD D G ++ Y QP F I G+++V
Sbjct: 73 FHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF--FAIDSARGIVTV 130
Query: 1105 NGELDRETEDKYILTVVA 1122
ELD ET Y LTV A
Sbjct: 131 IRELDYETTQAYQLTVNA 148
Score = 50.0 bits (114), Expect = 5e-04
Identities = 95/424 (22%), Positives = 166/424 (39%), Gaps = 50/424 (11%)
Query: 511 FKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI 570
F + P+TG V + + E + VE S S+ + V+T +V +
Sbjct: 19 FAVEPDTGVVWLRQPLDRETKSEFTVEFS-----VSDHQ---GVITRKVNIQVGDVNDNA 70
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF-AVEERSGVI 629
P F PY + N +GT + + D +L+ ++ F A++ G++
Sbjct: 71 PTFHNQPYSVRIPENTPVGTPIFIVNATDP--DLGAGGSVLYSFQPPSQFFAIDSARGIV 128
Query: 630 TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVK 689
TV+ +L Y L NA + I+ N + ++ + G II +
Sbjct: 129 TVIRELDYETTQAYQ-----LTVNAIIIIIINLP-YSTNIYEHSP---PGTTVRIITAID 179
Query: 690 ENSAGA-AIGQ-IFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD-R 746
++ IG I N +SI+ + ++ + + + G I T K +
Sbjct: 180 QDKGRPRGIGYTIVSGNTNSIFA--LDYISGVLTLNGLLDRENPLYSHGFILTVKGTELN 237
Query: 747 EKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
+ R TV FN I + D NDN P F + Y I E +++G +
Sbjct: 238 DDRTPSDATVTTTFN-------------ILVIDINDNAPEFNSSEYSVAITELAQVGFAL 284
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEMF-----DVDENTGVVKFIGDSLDREKKIMY 861
+ I+ D DEG N++F L G F V + + LD E Y
Sbjct: 285 PL--FIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRY 342
Query: 862 KLSLVARDT-GGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIE 920
L A ++ A++ I + +ENDN+P F+Q N + ++ + GT+ T++
Sbjct: 343 DFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYN--ISLYENVTV-GTSVLTVL- 398
Query: 921 VKPK 924
V P+
Sbjct: 399 VSPR 402
Score = 48.8 bits (111), Expect = 0.001
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRK-LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
I +D+D G+ + L+ N + S SV G + + + ++ + + +
Sbjct: 288 IQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET-VDRYDFDL 346
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
A++ + P A+V+I L++ NDN P F YNIS+ EN+ G SVL V+ + +
Sbjct: 347 FANE-SVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLVSPR 402
Score = 41.1 bits (92), Expect = 0.23
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKP 891
E F V+ +TGVV ++ LDRE K + + D G+ + ++ I +GD NDN P
Sbjct: 14 EASRFFAVEPDTGVV-WLRQPLDRETKSEFTVEFSVSDHQGVITR-KVNIQVGDVNDNAP 71
Query: 892 EFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
F+ + VRI T + GT F + P
Sbjct: 72 TFH--NQPYSVRIPENTPV-GTPIFIVNATDP 100
>UniRef50_O95206 Cluster: Protocadherin-8 precursor; n=16;
Tetrapoda|Rep: Protocadherin-8 precursor - Homo sapiens
(Human)
Length = 1070
Score = 88.6 bits (210), Expect = 1e-15
Identities = 143/596 (23%), Positives = 237/596 (39%), Gaps = 66/596 (11%)
Query: 589 GTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVPFAVEERSGVITVVD---DLSRY--NRP- 641
GT +G + + + D S+ L+ + + V E G +TV D D R P
Sbjct: 43 GTVIGTLAEDLHMKVSGDTSFRLMKQFNSSL-LRVREGDGQLTVGDAGLDRERLCGQAPQ 101
Query: 642 -MYDFEAVAL-QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ 699
+ F+ V+ QE L + V V DVND + A P+ E S GAA+G
Sbjct: 102 CVLAFDVVSFSQEQFRL---VHVEVEVRDVNDHAPRFPR-AQIPV-----EVSEGAAVGT 152
Query: 700 IFHTNM---SSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT----IFTQKPLDREKRDVY 752
+ + NG VR L ++ DG + + LDRE + Y
Sbjct: 153 RIPLEVPVDEDVGANGLQTVR-LAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAY 211
Query: 753 RMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVF-EHATYEGFIMENSKIGTEIKMDNI 811
+ ++A+ + G + +++ + D ND+ P F + A E + E++ +G+ + +D
Sbjct: 212 SLELVAQ-DGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGS-LLLD-- 267
Query: 812 IKATDADEGTNALFMYTLFG-----EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
+ A D DEG N ++ FG E + +F +D +G + G +D E++ Y+L +
Sbjct: 268 LDAADPDEGPNGDVVFA-FGARTPPEARRLFRLDPRSGRLTLAGP-VDYERQDTYELDVR 325
Query: 867 ARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK 924
A+D G ++ ++I+ I D NDN P+ + A +
Sbjct: 326 AQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADAS 385
Query: 925 NKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSAD 984
+ + G L+PE + + ++ D DSG NGQ+R + A
Sbjct: 386 SPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAG 445
Query: 985 ALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVND 1040
+ Y V+ A SL E +E+ L + A D G L V V D ND
Sbjct: 446 S-----YLVVT--------AASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDEND 492
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-------TDLPF 1093
+ P+F + Y +V E L V A D D G+N +TY + ++
Sbjct: 493 NAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYV 552
Query: 1094 EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
+ P TG + D ET + + + A D G D ND++P
Sbjct: 553 SVDPATGAIYALRSFDYETLRQLDVRIQASDGG-SPQLSSSALVQVRVLDQNDHAP 607
Score = 68.5 bits (160), Expect = 1e-09
Identities = 83/271 (30%), Positives = 113/271 (41%), Gaps = 37/271 (13%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFIS-RYYELEIEENVNAPVELVSLNLTE 1283
Q+ G P S+TA L V V D D P F E+E+ E+ L+ L+ +
Sbjct: 218 QDGGRPPRSATAALSVRVLDANDH-----SPAFPQGAVAEVELAEDAPVGSLLLDLDAAD 272
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
E N + + + RR F +DPR+G L L D E +DTYE+ VRA+
Sbjct: 273 PDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQ----- 327
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVT-AIPTTAPF--G 1398
D G KV+VRI+DVNDN+P PL P T+PF
Sbjct: 328 ------------DRGPGPRAATCKVIVRIRDVNDNAPDI--AITPLAAPGAPATSPFAAA 373
Query: 1399 YQVMQLKGAIGHHPTASRTVRADTDELV--FFERLSLNGLTSPQATDSDIGINADIRYQI 1456
L GA P + T A LV R SL L S +D D G N +R +
Sbjct: 374 AAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVS--TSDRDSGANGQVRCAL 431
Query: 1457 LNEQAPRFAIDPV-SGTVRVVAALARDAGRV 1486
+ F + P +G+ VV A + D R+
Sbjct: 432 YGHE--HFRLQPAYAGSYLVVTAASLDRERI 460
Score = 66.1 bits (154), Expect = 7e-09
Identities = 111/454 (24%), Positives = 179/454 (39%), Gaps = 50/454 (11%)
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
R+LF LD +G L L +D + + +T+ L V+A + A +V + + D+N
Sbjct: 294 RRLFRLDPRSGRLTLAGPVDYERQ-----DTYELDVRAQDRGPGPRAATCKVIVRIRDVN 348
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK-GAFSIDP--- 356
DN P+ + P A G + P+ GA S+ P
Sbjct: 349 DNAPDIAI---TPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGA 405
Query: 357 -RSGWLTVRNQTVLDREAHSSLRMKVYAKE---TNPSVVGTFADSQRIAKWRRQPLETNA 412
R + + + + D A+ +R +Y E P+ G++ + R + E N
Sbjct: 406 ARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNL 465
Query: 413 PLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSN 472
T V D+ + Y V + D NDN P+F +YE S++ N
Sbjct: 466 -----TLVAEDRGAPPLRTVRPYT----------VRVGDENDNAPLFTRP-VYEVSVREN 509
Query: 473 AKVGTVIGKVKAVDPDLGQNGMVLYDLQRT----SNLTITSPFKINPNTGTVSVAESPIL 528
G + V A D DLG+NG V Y L + +++ ++P TG + S
Sbjct: 510 NPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDY 569
Query: 529 EGRHALFV--EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI--PDFMGAPYEFWVGS 584
E L V +ASD S + S A+V + V + P + P E V
Sbjct: 570 ETLRQLDVRIQASD---GGSPQLSSSALVQVRVL-DQNDHAPVLVHPAPANGSLEVAVPG 625
Query: 585 NVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPM 642
T V +++ DA E +++++ L E FA+ R+G I + DLS+ P
Sbjct: 626 RTAKDTVVARVQARDADEGANGELAFE-LQQQEPREAFAIGRRTGEILLTGDLSQ-EPPG 683
Query: 643 YDFEA-VALQENANLSIVTNATV-HVVDVNDERG 674
F A + + + + T ATV VV RG
Sbjct: 684 RVFRALLVISDGGRPPLTTTATVSFVVTAGGGRG 717
Score = 62.9 bits (146), Expect = 7e-08
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 15/196 (7%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN P G + + A D D G NGQ+ Y + +++ V Y ++ G
Sbjct: 506 VRENNPPGAYLATVAARDRDLGRNGQVTYR------LLEAEVGRAGGAVSTYVSVDPATG 559
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVF-KKTWYNFNV 1054
+ RS E+ + + I A DGG+ L+ + V+V V D NDH PV N ++
Sbjct: 560 AIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSL 619
Query: 1055 EEAQYTRR----VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
E A R V+ +V A DAD G N L + +Q + F I TG + + G+L +
Sbjct: 620 EVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQ 679
Query: 1111 ETEDKYILTVVARDNG 1126
E + ++ +G
Sbjct: 680 EPPGRVFRALLVISDG 695
Score = 58.0 bits (134), Expect = 2e-06
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 221 IDQDLGVGATLRYELISGNDRKLFSLDS-VNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
+D+D+G L + L + +G+ + L + + QA + L++ A
Sbjct: 160 VDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQA-AYSLELVAQ 218
Query: 280 QLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
P ++A A + + +LD ND+ P F + + + E+ P G +L + A D D+G N
Sbjct: 219 DGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPN 278
Query: 339 GE--FTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
G+ F + P A F +DPRSG LT+ +D E + + V A++ P
Sbjct: 279 GDVVFAFGARTPPEARRLFRLDPRSGRLTLAGP--VDYERQDTYELDVRAQDRGP 331
Score = 56.4 bits (130), Expect = 6e-06
Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V +LDAND++P F + E + +A VG+++ + A DPD G NG V++ +
Sbjct: 231 LSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTP 290
Query: 505 LTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTK 564
F+++P +G +++A E + ++ Q P R + V+ + + R
Sbjct: 291 PEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVI-VRI-RDVN 348
Query: 565 GNKPDI 570
N PDI
Sbjct: 349 DNAPDI 354
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN-TFVLQVQASQ 280
D+D G +R L +L + GS + LD E + N T V + + +
Sbjct: 418 DRDSGANGQVRCALYGHEHFRL--QPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAP 475
Query: 281 LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
PL+T + + + D NDN P F Y +S+ EN P G + V A D+D G NG+
Sbjct: 476 ---PLRTVRPYT-VRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQ 531
Query: 341 FTYQL 345
TY+L
Sbjct: 532 VTYRL 536
Score = 51.6 bits (118), Expect = 2e-04
Identities = 40/156 (25%), Positives = 71/156 (45%), Gaps = 19/156 (12%)
Query: 218 IHAIDQDLGVGATLRYELIS-------GNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
+ A D+DLG + Y L+ G S+D G+++ + D + L
Sbjct: 519 VAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLD-- 576
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF-----EVDFYNISIVENLPNGFSV 325
+++QAS +P ++ A V++ +LD ND+ P +++ V
Sbjct: 577 ---VRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVV 633
Query: 326 LQVMATDKDQGENGEFTYQL--DDPKGAFSIDPRSG 359
+V A D D+G NGE ++L +P+ AF+I R+G
Sbjct: 634 ARVQARDADEGANGELAFELQQQEPREAFAIGRRTG 669
Score = 47.6 bits (108), Expect = 0.003
Identities = 54/166 (32%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query: 438 QLMSFVNVEVTLLDANDNNPVFV---PSN-LYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
QL S V+V +LD ND+ PV V P+N E ++ TV+ +V+A D D G NG
Sbjct: 588 QLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANG 647
Query: 494 MVLYDLQRTSNLTITSPFKINPNTG----TVSVAESPILEGRHALFVEASDQPANPSERR 549
+ ++LQ+ F I TG T +++ P AL V SD P
Sbjct: 648 ELAFELQQQEP---REAFAIGRRTGEILLTGDLSQEPPGRVFRALLV-ISDGGRPPLT-- 701
Query: 550 YSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFW-VGSNVGIGTSVGQ 594
+ A V+ VT G G P P G+P GS +G+ SV Q
Sbjct: 702 -TTATVSFVVTAG-GGRGPAAPASAGSPERSRPPGSRLGVSGSVLQ 745
Score = 45.6 bits (103), Expect = 0.011
Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 10/130 (7%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD 1088
+ V V V+DVNDH P F + V E + D D G N T ++ ++
Sbjct: 119 VHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQT--VRLAE 176
Query: 1089 TDLPFEISPLTGV-------LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXX 1141
PF + T L + ELDRE++ Y L +VA+D G
Sbjct: 177 PHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGG-RPPRSATAALSVRV 235
Query: 1142 XDVNDNSPKF 1151
D ND+SP F
Sbjct: 236 LDANDHSPAF 245
Score = 44.8 bits (101), Expect = 0.018
Identities = 64/271 (23%), Positives = 102/271 (37%), Gaps = 15/271 (5%)
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDV 669
L+G+E S ++ L R Y+ VA A L V TV V D
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDE 490
Query: 670 NDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDD 729
ND + + + V+EN+ A + NG R L A
Sbjct: 491 NDNAPLFTRPVYE---VSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGA 547
Query: 730 IA--IAED---GTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDN 783
++ ++ D G I+ + D E R + ++ +S + + QV + D+ND+
Sbjct: 548 VSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVL--DQNDH 605
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNI--IKATDADEGTNALFMYTLFG-EGKEMFDVD 840
PV H +E + G K + ++A DADEG N + L E +E F +
Sbjct: 606 APVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIG 665
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
TG + GD +++ LV D G
Sbjct: 666 RRTGEILLTGDLSQEPPGRVFRALLVISDGG 696
Score = 40.7 bits (91), Expect = 0.30
Identities = 68/291 (23%), Positives = 112/291 (38%), Gaps = 21/291 (7%)
Query: 435 YDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGM 494
+ ++ V+VEV + D ND+ P F P + A VGT I VD D+G NG
Sbjct: 111 FSQEQFRLVHVEVEVRDVNDHAPRF-PRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANG- 168
Query: 495 VLYDLQRTSNLTITSPFKINPNTGT--VSVAESPILE--GRHALFVEASDQPANPSER-- 548
LQ SPF++ T A+ +L+ R + + + A R
Sbjct: 169 ----LQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPP 224
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV 606
R + A +++ V + P P GA E + + +G+ + + D E DV
Sbjct: 225 RSATAALSVRVL-DANDHSPAFP--QGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDV 281
Query: 607 --SYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NAT 663
++ E F ++ RSG +T+ + + Y+ + A T
Sbjct: 282 VFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVI 341
Query: 664 VHVVDVNDER-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
V + DVND + + +P +A AA + + SS G GT
Sbjct: 342 VRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGT 392
Score = 39.1 bits (87), Expect = 0.92
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
VE+E+ D+ND+ P F + + E G + + D+D G NG T +L +P
Sbjct: 121 VEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSP 180
Query: 352 FSID--PRSGWLTVRNQTV---LDREAHSSLRMKVYAKE-TNPSVVGTFADSQRI 400
F ++ R+ + + LDRE+ ++ +++ A++ P T A S R+
Sbjct: 181 FRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRV 235
>UniRef50_Q86UP0 Cluster: Cadherin-24 precursor; n=17;
Euteleostomi|Rep: Cadherin-24 precursor - Homo sapiens
(Human)
Length = 819
Score = 88.6 bits (210), Expect = 1e-15
Identities = 62/214 (28%), Positives = 95/214 (44%), Gaps = 7/214 (3%)
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
F V E AG + + S G G ++L+ + T + G I K LD
Sbjct: 51 FFVIEEYAGPE--PVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLD 108
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE++ Y + A + I ++D NDNPP+F Y + E S +GT
Sbjct: 109 REEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTS 168
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ A D G +A +YT+ +G F VD TGVV+ ++DRE + + + +
Sbjct: 169 VIQVTAHDADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVI 227
Query: 866 VARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
A+D GGLS + + + D NDN P+F Q
Sbjct: 228 QAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQ 261
Score = 81.4 bits (192), Expect = 2e-13
Identities = 61/217 (28%), Positives = 98/217 (45%), Gaps = 6/217 (2%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V VTL D NDN P F P +LY+FS+ A GT++G+++A DPDLG N ++ Y
Sbjct: 239 LSGSTTVTVTLSDVNDNPPKF-PQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYS 297
Query: 499 -LQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
L + + + G ++V + E + ++ VEA++ +P+ R
Sbjct: 298 ILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG-PFK 356
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGY 614
+ R + P+ P F A Y V N GT VGQI D + + Y +L
Sbjct: 357 DVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHS 416
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
+ F+++ G I L R R ++ +A +
Sbjct: 417 DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATE 453
Score = 79.8 bits (188), Expect = 5e-13
Identities = 73/271 (26%), Positives = 124/271 (45%), Gaps = 19/271 (7%)
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVV 667
LL G G F ++E +G I V L R + Y A A+ +N L + + V
Sbjct: 82 LLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQ 141
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIF-HTNMSSIYGNGTGNVRFLIANQQDV 726
D+ND + G + + + ++ G ++ Q+ H YGN V ++
Sbjct: 142 DINDNPPIFPLGPYHATVPEM--SNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFF 199
Query: 727 TDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNP 784
+ D + G + T P +DRE ++ + + + A+ G + G +G VT+ + D NDNP
Sbjct: 200 SVD---PQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNP 256
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMF----DV 839
P F + Y+ ++E + GT + ++A D D G NAL Y++ GEG E F D+
Sbjct: 257 PKFPQSLYQFSVVETAGPGTLV---GRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDL 313
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
G++ + LD E + Y + A +T
Sbjct: 314 QGRDGLLT-VRKPLDFESQRSYSFRVEATNT 343
Score = 75.4 bits (177), Expect = 1e-11
Identities = 97/379 (25%), Positives = 164/379 (43%), Gaps = 42/379 (11%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
FVI+E G++ V +SL E +++ L A+D + L + V+D+ND+ P+F
Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLP-FEISPLTGVL 1102
Y+ V E + +V A DAD +G +A L Y + LP F + P TGV+
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDG---LPFFSVDPQTGVV 208
Query: 1103 -SVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEW 1160
+ +DRET++++++ + A+D G DVNDN PKF L ++
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFP--QSLYQF 266
Query: 1161 KHPEADELSNHNFESVMMIPVYKATIEENAPIGTTV-----AKVFANDTDFIGNGNGLIL 1215
E V + + +NA + ++ ++ F+ TD G +GL+
Sbjct: 267 SVVETAGPGT----LVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGR-DGLLT 321
Query: 1216 YSLP-QRKNQQNLGLPSLSSTAIL---------MVTVADVPDEV-EMSDKPVFISRYYEL 1264
P ++Q++ ++ ++ VA V V + + P F Y L
Sbjct: 322 VRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHL 381
Query: 1265 EIEENVNAPVELVSLNLTEHYEN--FKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPD 1322
+ EN AP LV ++ +RY IL +D + R F I P GT++ D
Sbjct: 382 TVPEN-KAPGTLVGQISAADLDSPASPIRYSILPHSDPE--RCFSIQPEEGTIHTAAPLD 438
Query: 1323 REVKDTYEVIVRAERQKYS 1341
RE + + + V A +S
Sbjct: 439 REARAWHNLTVLATELGWS 457
Score = 70.5 bits (165), Expect = 3e-10
Identities = 88/332 (26%), Positives = 141/332 (42%), Gaps = 38/332 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P+F P Y ++ + VGT + +V A D P G + ++Y +
Sbjct: 138 IKVQDINDNPPIF-PLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTV---- 192
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F ++P TG V A + + + ++A D + S T+ VT
Sbjct: 193 -LDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGS---TTVTVT 248
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHGYEEGV 618
+ P P F + Y+F V G GT VG++R D ++ ++Y +L G E
Sbjct: 249 LSDVNDNP--PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG-EGSE 305
Query: 619 PFAV----EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F++ + R G++TV L ++ Y F A + + + DV R
Sbjct: 306 AFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFK--DVASVRV 363
Query: 675 VLLKGAHSPII----FH--VKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ P +H V EN A G +GQI ++ S +R+ I D
Sbjct: 364 AVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDS----PASPIRYSILPHSDPE 419
Query: 728 DDIAIA-EDGTIFTQKPLDREKRDVYRMTVIA 758
+I E+GTI T PLDRE R + +TV+A
Sbjct: 420 RCFSIQPEEGTIHTAAPLDREARAWHNLTVLA 451
Score = 70.1 bits (164), Expect = 4e-10
Identities = 114/448 (25%), Positives = 173/448 (38%), Gaps = 44/448 (9%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLI-----APIGPSLTIPLTVPRGLT 139
+ ++D+NDN PIF PYH TV E++ G G S + TV GL
Sbjct: 138 IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP 197
Query: 140 IFKDIRAFDRDKPNTPNSDVHYS-----IVSGND-DGHFALESSHKPVLLLRKVLDYDAG 193
F + PN D ++ D GH S V + ++ D
Sbjct: 198 FFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVN-DNP 256
Query: 194 DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFS----LDSV 249
K Q + S + A D DLG A + Y ++ G + FS L
Sbjct: 257 PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGR 316
Query: 250 NGSLFLEKELDLDAEHNLQAN---TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
+G L + K LD +++ + T L A P K A V + + D + P F
Sbjct: 317 DGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV-ASVRVAVQDAPEP-PAF 374
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTV 363
Y++++ EN G V Q+ A D D + Y + DP+ FSI P G T+
Sbjct: 375 TQAAYHLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHSDPERCFSIQPEEG--TI 431
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFA-DSQRIAKWRRQPLETNAPLEKTTYVFP 422
LDREA + + V A E S +A+W AP +++
Sbjct: 432 HTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPA----APPQRS----- 482
Query: 423 DKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKV 482
VG+ I S V V + LD NDN P + Y+ + +A G +I +
Sbjct: 483 -PVGSAV-GIPQDSSAQASRVQVAIQTLDENDNAPQL--AEPYDTFVCDSAAPGQLIQVI 538
Query: 483 KAVDPD-LGQNGMVLYD--LQRTSNLTI 507
+A+D D +G + V + L +N T+
Sbjct: 539 RALDRDEVGNSSHVSFQGPLGPDANFTV 566
Score = 63.3 bits (147), Expect = 5e-08
Identities = 62/201 (30%), Positives = 95/201 (47%), Gaps = 24/201 (11%)
Query: 934 LGPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYF 992
LGP +PE +GT++I++ A D D G NS +KL L+ +F
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYG------NS------AKLVYTVLDGLPFF 199
Query: 993 VINERHGHVIVA---RSLPPESEFRLNISALD-GGN---LNDNISVRVFVKDVNDHFPVF 1045
++ + G V A + EF + I A D GG+ L+ + +V V + DVND+ P F
Sbjct: 200 SVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKF 259
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP----LTGV 1101
++ Y F+V E ++G++ A D D G NA + Y I + F IS G+
Sbjct: 260 PQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGL 319
Query: 1102 LSVNGELDRETEDKYILTVVA 1122
L+V LD E++ Y V A
Sbjct: 320 LTVRKPLDFESQRSYSFRVEA 340
Score = 62.5 bits (145), Expect = 9e-08
Identities = 57/186 (30%), Positives = 88/186 (47%), Gaps = 19/186 (10%)
Query: 210 KEILFPEPI-----HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAE 264
+E PEP+ H+ D D G G T +Y L +F +D G++ + K LD E
Sbjct: 55 EEYAGPEPVLIGKLHS-DVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLD--RE 110
Query: 265 HNLQANTFVLQVQASQL--NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNG 322
Q +VL QA N PL+ + I++ D+NDN P F + Y+ ++ E G
Sbjct: 111 EKAQ---YVLLAQAVDRASNRPLEPPSEFI-IKVQDINDNPPIFPLGPYHATVPEMSNVG 166
Query: 323 FSVLQVMATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRM 379
SV+QV A D D G + + Y + D FS+DP++G + +DRE +
Sbjct: 167 TSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPN-MDRETQEEFLV 225
Query: 380 KVYAKE 385
+ AK+
Sbjct: 226 VIQAKD 231
Score = 62.1 bits (144), Expect = 1e-07
Identities = 96/412 (23%), Positives = 173/412 (41%), Gaps = 38/412 (9%)
Query: 478 VIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALF 535
+IGK+ + D D G+ G Y L T+ F I+ TG + V +S E ++ L
Sbjct: 64 LIGKLHS-DVDRGE-GRTKYLLTGEGAGTV---FVIDEATGNIHVTKSLDREEKAQYVLL 118
Query: 536 VEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI 595
+A D+ +N S ++ ++ N P P +G PY V +GTSV Q+
Sbjct: 119 AQAVDRASNRPLEPPSEFIIKVQ---DINDNPPIFP--LG-PYHATVPEMSNVGTSVIQV 172
Query: 596 RVNDAFEQN-DVSYDLLHGYEEGVPF-AVEERSGVI-TVVDDLSRYNRPMYDFEAVALQE 652
+DA + + S L++ +G+PF +V+ ++GV+ T + ++ R + + A
Sbjct: 173 TAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDM 232
Query: 653 NANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGN 711
++ ++ +T V ++D K S F V E + G +G++ + N
Sbjct: 233 GGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRL-RAQDPDLGDN 291
Query: 712 GTGNVRFLIANQQD---VTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA 768
L + ++ D+ DG + +KPLD E + Y V E +I A
Sbjct: 292 ALMAYSILDGEGSEAFSISTDLQ-GRDGLLTVRKPLDFESQRSYSFRV--EATNTLIDPA 348
Query: 769 --------GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEG 820
+ V + ++D + PP F A Y + EN GT + I A D D
Sbjct: 349 YLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQ---ISAADLDSP 404
Query: 821 TNAL-FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+ + + + + F + G + LDRE + + L+++A + G
Sbjct: 405 ASPIRYSILPHSDPERCFSIQPEEGTI-HTAAPLDREARAWHNLTVLATELG 455
Score = 39.5 bits (88), Expect = 0.69
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 21/126 (16%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
FVID G +++ +S DRE K Y ++ +A + +R L P +E
Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLE----PPSE------------ 135
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPT---ASRTVRADT 1422
+++++D+NDN P F G P +P + G V+Q+ P+ +++ V
Sbjct: 136 FIIKVQDINDNPPIFPLG--PYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVL 193
Query: 1423 DELVFF 1428
D L FF
Sbjct: 194 DGLPFF 199
Score = 37.5 bits (83), Expect = 2.8
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 3/101 (2%)
Query: 1052 FNVEEAQYTRRVL-GKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F +EE VL GK+ + D D G+ Y + F I TG + V LDR
Sbjct: 52 FVIEEYAGPEPVLIGKLHS-DVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLDR 109
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E + +Y+L A D D+NDN P F
Sbjct: 110 EEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIF 150
>UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadherin
8; n=1; Monodelphis domestica|Rep: PREDICTED: similar to
protocadherin 8 - Monodelphis domestica
Length = 955
Score = 88.2 bits (209), Expect = 2e-15
Identities = 112/433 (25%), Positives = 183/433 (42%), Gaps = 36/433 (8%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A++ + + LDRE + Y + ++A+ + G + +++ + D ND+ PVF ++
Sbjct: 254 AKNADLLLLQELDRESQANYSLELVAQ-DGGDPPRSATAVLSVRVLDANDHSPVFPLGSF 312
Query: 793 -EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG----EGKEMFDVDENTGVVK 847
E + E+S G+ + +D I ATD DEG + +++ G E + F +D +G +
Sbjct: 313 IEVEVSEDSPEGS-LLLD--IDATDPDEGPSGDVVFSFGGRTPPEAQLPFHLDPRSGHLT 369
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
+ LD E+K Y+L ++A+D G S S ++I+ I D NDN P I V
Sbjct: 370 -LTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNAPVITIIPLVMAVNTA 428
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLG-PLFLIPENIPIGTTIIKLNALDLDSGLNG 964
+ + A + +P Q G L LIPE + + ++ LD DS NG
Sbjct: 429 SDYSSSFAAPVSASWEEPGG------PQSGVALSLIPEGAAQESLVALVSTLDRDSDSNG 482
Query: 965 QIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN 1024
Q+ + A + Y V+ + R PE L L
Sbjct: 483 QVHCALYGHEHFRLQPAYAGS-----YLVLTT----TPLDRERIPEYNLTLVAQDLGSPP 533
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
L+ V V D ND+ P+F + Y +V E + L V A D D G+N +TY +
Sbjct: 534 LSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNGKVTYRL 593
Query: 1085 ----QPSDTDLP---FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
+ D DL + +GVL DRE + + + ARD G
Sbjct: 594 LETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGG-SPSQWGQTVV 652
Query: 1138 XXXXXDVNDNSPK 1150
D ND++P+
Sbjct: 653 RLVVEDQNDHAPE 665
Score = 70.1 bits (164), Expect = 4e-10
Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 18/180 (10%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDS-----VNGSLFLEKELDLDAEHNLQANTFVL 274
A+D+D+G A L+ + L + N L L +ELD +++ N + L
Sbjct: 221 AVDEDVGSNALQSLRLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQAN-----YSL 275
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDK 333
++ A +P ++A A + + +LD ND+ P F + F + + E+ P G +L + ATD
Sbjct: 276 ELVAQDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDP 335
Query: 334 DQGENGE--FTYQLDDPKGA---FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D+G +G+ F++ P A F +DPRSG LT+ LD E + + V A++ P
Sbjct: 336 DEGPSGDVVFSFGGRTPPEAQLPFHLDPRSGHLTLTRP--LDYEQKETYELDVMAQDQGP 393
Score = 70.1 bits (164), Expect = 4e-10
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 15/172 (8%)
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
A A + T PLDRE+ Y +T++A+ + G + + T+ + DENDN P+F
Sbjct: 499 AYAGSYLVLTTTPLDRERIPEYNLTLVAQ-DLGSPPLSTMRPYTVRVADENDNAPLFARP 557
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF----GEGKEM----FDVDEN 842
YE ++EN+ G + + A D D G N Y L G+ +++ VD +
Sbjct: 558 VYEVSVLENNFPGAYL---TTVVARDPDLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSD 614
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELII--MIGDENDNKPE 892
+GV++ DRE +++L ARD G S + ++ ++ D+ND+ PE
Sbjct: 615 SGVLR-ARRRFDREALAELEVALEARDGGSPSQWGQTVVRLVVEDQNDHAPE 665
Score = 68.1 bits (159), Expect = 2e-09
Identities = 64/239 (26%), Positives = 106/239 (44%), Gaps = 17/239 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
+EV+ N + + L + E+ +GT I A+D D G N S + P
Sbjct: 185 VEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNA-----LQSLRLVEP 239
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALDGGNLNDNIS--VRVF 1034
L+ + ++ +++ + L ES+ + L + A DGG+ + + + V
Sbjct: 240 HSFFRVELQTR---ADGAKNADLLLLQELDRESQANYSLELVAQDGGDPPRSATAVLSVR 296
Query: 1035 VKDVNDHFPVFKK-TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI---QPSDTD 1090
V D NDH PVF ++ V E +L +DATD D G + ++ + P +
Sbjct: 297 VLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPPEAQ 356
Query: 1091 LPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
LPF + P +G L++ LD E ++ Y L V+A+D G DVNDN+P
Sbjct: 357 LPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQG-PGSRVSTCKVIVHILDVNDNAP 414
Score = 62.9 bits (146), Expect = 7e-08
Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 20/162 (12%)
Query: 220 AIDQDLGVGATLRYELIS---GNDRKLFS----LDSVNGSLFLEKELDLDAEHNLQANTF 272
A D DLG + Y L+ G DR L S +DS +G L + D +A L+
Sbjct: 578 ARDPDLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELE---- 633
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-----ISIVENLPNGFSVLQ 327
+ ++A +P + Q V + + D ND+ PE + + + +P GF V +
Sbjct: 634 -VALEARDGGSPSQWGQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTR 692
Query: 328 VMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQ 366
V A D+D+G N E TY L D GA ++ P +G L++R Q
Sbjct: 693 VQARDEDEGPNAELTYSLTHSDGDPGALALHPHTGELSLRRQ 734
Score = 56.4 bits (130), Expect = 6e-06
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 686 FHV-KENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFT--QK 742
+H+ +E G IG + + G N R + +Q T I ++ED T +
Sbjct: 98 YHIYEEEIPGTVIGVLSAHTRADSPGMVPRNFRLM---KQFNTSLIRLSEDDGQLTVGEN 154
Query: 743 PLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
+DRE+ F+ V+S + + V + + D ND+ P F + + E++ +
Sbjct: 155 GIDREQLCQQSQQCTLTFD--VVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAV 212
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENT------GVVKFIGDSLDRE 856
GT I ++ A D D G+NAL L E F V+ T + LDRE
Sbjct: 213 GTRIPLE---VAVDEDVGSNALQSLRLV-EPHSFFRVELQTRADGAKNADLLLLQELDRE 268
Query: 857 KKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
+ Y L LVA+D G S+ A L + + D ND+ P F
Sbjct: 269 SQANYSLELVAQDGGDPPRSATAVLSVRVLDANDHSPVF 307
Score = 56.0 bits (129), Expect = 7e-06
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 17/198 (8%)
Query: 939 LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERH 998
++ N P G + + A D D G NG++ Y + +K D V Y ++
Sbjct: 563 VLENNFP-GAYLTTVVARDPDLGRNGKVTYR------LLETKEGQDRDLVSAYVSVDSDS 615
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLND--NISVRVFVKDVNDH-----FPVFKKTW 1049
G + R E+ E + + A DGG+ + VR+ V+D NDH FP+
Sbjct: 616 GVLRARRRFDREALAELEVALEARDGGSPSQWGQTVVRLVVEDQNDHAPEVIFPLLSNGS 675
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDL-PFEISPLTGVLSVNGEL 1108
+ ++ +V A D D G NA LTY + SD D + P TG LS+ +L
Sbjct: 676 ALVPLPRGVPPGFLVTRVQARDEDEGPNAELTYSLTHSDGDPGALALHPHTGELSLRRQL 735
Query: 1109 DRETEDKYILTVVARDNG 1126
D L V +DNG
Sbjct: 736 SPWPIDPLTLVVTVQDNG 753
Score = 54.8 bits (126), Expect = 2e-05
Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 27/176 (15%)
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVF-ISRYYELEIEENVNAPVELVSLNLTE 1283
Q+ G P S+TA+L V V D D PVF + + E+E+ E+ L+ ++ T+
Sbjct: 280 QDGGDPPRSATAVLSVRVLDANDH-----SPVFPLGSFIEVEVSEDSPEGSLLLDIDATD 334
Query: 1284 HYE--NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYS 1341
E + + + + + F +DPR+G L L R D E K+TYE+ V
Sbjct: 335 PDEGPSGDVVFSFGGRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDV-------- 386
Query: 1342 RELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPF 1397
+A+D G KV+V I DVNDN+P T PLV A+ T + +
Sbjct: 387 ---------MAQDQGPGSRVSTCKVIVHILDVNDNAPVIT--IIPLVMAVNTASDY 431
Score = 54.8 bits (126), Expect = 2e-05
Identities = 45/144 (31%), Positives = 68/144 (47%), Gaps = 14/144 (9%)
Query: 251 GSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDF 310
GS + LD E + N L + A L +P + + + D NDN P F
Sbjct: 502 GSYLVLTTTPLDRERIPEYN---LTLVAQDLGSPPLSTMRPYTVRVADENDNAPLFARPV 558
Query: 311 YNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK--------GAF-SIDPRSGWL 361
Y +S++EN G + V+A D D G NG+ TY+L + K A+ S+D SG L
Sbjct: 559 YEVSVLENNFPGAYLTTVVARDPDLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVL 618
Query: 362 TVRNQTVLDREAHSSLRMKVYAKE 385
R + DREA + L + + A++
Sbjct: 619 RARRR--FDREALAELEVALEARD 640
Score = 51.6 bits (118), Expect = 2e-04
Identities = 64/248 (25%), Positives = 107/248 (43%), Gaps = 26/248 (10%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
++VEV + D ND++P F S + + +A VGT I AVD D+G N LQ
Sbjct: 181 IHVEVEVRDINDHSPRFPRSQIL-VEVSESAAVGTRIPLEVAVDEDVGSNA-----LQSL 234
Query: 503 SNLTITSPFKINPNTGTVSVAESPIL---------EGRHALFVEASDQPANPSERRYSLA 553
+ S F++ T + +L + ++L + A D P R + A
Sbjct: 235 RLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDPP---RSATA 291
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDV--SYD 609
V+++ V + P P +G+ E V + G+ + I D E DV S+
Sbjct: 292 VLSVRVL-DANDHSPVFP--LGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFG 348
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVD 668
E +PF ++ RSG +T+ L + Y+ + +A + + T VH++D
Sbjct: 349 GRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILD 408
Query: 669 VNDERGVL 676
VND V+
Sbjct: 409 VNDNAPVI 416
Score = 50.0 bits (114), Expect = 5e-04
Identities = 62/261 (23%), Positives = 106/261 (40%), Gaps = 25/261 (9%)
Query: 244 FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNL 303
F LD +G L L + LD + Q T+ L V A + + +V + +LD+NDN
Sbjct: 359 FHLDPRSGHLTLTRPLDYE-----QKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNA 413
Query: 304 PEFEVD--FYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWL 361
P + ++ + + F+ + ++ G L P+GA + +
Sbjct: 414 PVITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLI-PEGA----AQESLV 468
Query: 362 TVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVF 421
+ + D +++ + +Y E + + +A S + T PL++
Sbjct: 469 ALVSTLDRDSDSNGQVHCALYGHE-HFRLQPAYAGSYLVL--------TTTPLDRER--I 517
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
P+ T + L + V + D NDN P+F +YE S+ N G +
Sbjct: 518 PEYNLTLVAQ-DLGSPPLSTMRPYTVRVADENDNAPLFARP-VYEVSVLENNFPGAYLTT 575
Query: 482 VKAVDPDLGQNGMVLYDLQRT 502
V A DPDLG+NG V Y L T
Sbjct: 576 VVARDPDLGRNGKVTYRLLET 596
Score = 45.2 bits (102), Expect = 0.014
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 6/128 (4%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNA-NLTYFIQPS 1087
I V V V+D+NDH P F ++ V E+ + A D D G NA ++P
Sbjct: 181 IHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQSLRLVEPH 240
Query: 1088 D---TDLPFEISPLTGV-LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
+L L + ELDRE++ Y L +VA+D G D
Sbjct: 241 SFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGG-DPPRSATAVLSVRVLD 299
Query: 1144 VNDNSPKF 1151
ND+SP F
Sbjct: 300 ANDHSPVF 307
Score = 41.9 bits (94), Expect = 0.13
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 11/163 (6%)
Query: 629 ITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
+ ++ +L R ++ Y E VA Q+ + S +V V+D ND V G+ +
Sbjct: 259 LLLLQELDRESQANYSLELVA-QDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEV-- 315
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFTQKP 743
V E+S ++ + + + +G+V F + + D G + +P
Sbjct: 316 EVSEDSPEGSL--LLDIDATDPDEGPSGDVVFSFGGRTPPEAQLPFHLDPRSGHLTLTRP 373
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPV 786
LD E+++ Y + V+A+ ++G S +V ++I D NDN PV
Sbjct: 374 LDYEQKETYELDVMAQ-DQGPGSRVSTCKVIVHILDVNDNAPV 415
Score = 39.5 bits (88), Expect = 0.69
Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGA 351
VE+E+ D+ND+ P F + + E+ G + +A D+D G N + +L +P
Sbjct: 183 VEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQSLRLVEPHSF 242
Query: 352 FSIDPRSGWLTVRNQTV-----LDREAHSSLRMKVYAKE 385
F ++ ++ +N + LDRE+ ++ +++ A++
Sbjct: 243 FRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQD 281
Score = 35.9 bits (79), Expect = 8.6
Identities = 54/236 (22%), Positives = 97/236 (41%), Gaps = 12/236 (5%)
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVT 660
+ N + L+G+E S ++ L R P Y+ VA + LS +
Sbjct: 479 DSNGQVHCALYGHEHFRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVAQDLGSPPLSTMR 538
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
TV V D ND + + + + ++ N GA + + + + NG R L
Sbjct: 539 PYTVRVADENDNAPLFARPVYEVSV--LENNFPGAYLTTVVARD-PDLGRNGKVTYRLLE 595
Query: 721 ANQ-QD---VTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+ QD V+ +++ D G + ++ DRE + + A + G S G V +
Sbjct: 596 TKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEAR-DGGSPSQWGQTVVRL 654
Query: 776 YIEDENDNPP--VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+ED+ND+ P +F + ++ + + ++A D DEG NA Y+L
Sbjct: 655 VVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELTYSL 710
>UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadherin)
(Uvomorulin) (Cadherin-1) (CAM 120/80) (CD324 antigen)
[Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3]; n=52;
Tetrapoda|Rep: Epithelial cadherin precursor
(E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80)
(CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E-
Cad/CTF3] - Homo sapiens (Human)
Length = 882
Score = 87.8 bits (208), Expect = 2e-15
Identities = 68/210 (32%), Positives = 100/210 (47%), Gaps = 20/210 (9%)
Query: 701 FHTNMSSIYGNGT--GNVRFLIANQQDVTDDIAI----AEDGTIFTQKPLDREKRDVYRM 754
F N+ I N G V + I Q T + + E G + +PLDRE+ Y +
Sbjct: 171 FPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTL 230
Query: 755 TVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
A + G + ++ I + D+NDN P F ++G +ME + GT + M+ + A
Sbjct: 231 FSHAVSSNGNAVEDPM-EILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSV-ME--VTA 286
Query: 815 TDADEGT---NALFMYTLFGE-----GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLV 866
TDAD+ NA YT+ + K MF ++ NTGV+ + LDRE Y L +
Sbjct: 287 TDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQ 346
Query: 867 ARDT--GGLSSEAELIIMIGDENDNKPEFN 894
A D GLS+ A +I + D NDN P FN
Sbjct: 347 AADLQGEGLSTTATAVITVTDTNDNPPIFN 376
Score = 54.4 bits (125), Expect = 2e-05
Identities = 53/172 (30%), Positives = 74/172 (43%), Gaps = 13/172 (7%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISAL--DGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F+I G + V L E + + L A+ +G + D + + + V D ND+ P F +
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFG---QNANLTYFIQPSDTDLP----FEISPLTG 1100
+ +V E + +V ATDAD NA + Y I D +LP F I+ TG
Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324
Query: 1101 VLS-VNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
V+S V LDRE+ Y L V A D D NDN P F
Sbjct: 325 VISVVTTGLDRESFPTYTLVVQAADL-QGEGLSTTATAVITVTDTNDNPPIF 375
Score = 50.8 bits (116), Expect = 3e-04
Identities = 89/369 (24%), Positives = 145/369 (39%), Gaps = 35/369 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD---LGQNGMVLYD- 498
+ + +T+ D NDN P F +++ S+ A GT + +V A D D N + Y
Sbjct: 246 MEILITVTDQNDNKPEFT-QEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI 304
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRYSLAVV 555
L + L + F IN NTG +SV + + + L V+A+D E + A
Sbjct: 305 LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADL---QGEGLSTTATA 361
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGY- 614
I VT T N P F Y+ V N + ++V DA N +++ ++
Sbjct: 362 VITVT-DTNDNP---PIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTIL 416
Query: 615 -EEGVPFAVE----ERSGVITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVD 668
++G F V G++ L + Y AV +S+ T+ VD
Sbjct: 417 NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVD 476
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
V D + + E S +GQ T+ ++ + + +D +
Sbjct: 477 VLDVNEAPIFVPPEKRV----EVSEDFGVGQEI-TSYTAQEPDTFMEQKITYRIWRDTAN 531
Query: 729 DIAIAED-GTIFTQKPLDRE-----KRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ I D G I T+ LDRE K Y +IA N ++ G + + + D ND
Sbjct: 532 WLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVA-TGTGTLLLILSDVND 590
Query: 783 NPPVFEHAT 791
N P+ E T
Sbjct: 591 NAPIPEPRT 599
Score = 48.4 bits (110), Expect = 0.002
Identities = 62/256 (24%), Positives = 98/256 (38%), Gaps = 20/256 (7%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLK 678
F +E +G + V + L R Y + A+ N N + + V D ND + +
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI----AE 734
+ ++ G ++ ++ T+ + + I +Q D +
Sbjct: 265 EVFKGSV--MEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRN 322
Query: 735 DGTI-FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
G I LDRE Y + V A +G V I + D NDNPP+F TY+
Sbjct: 323 TGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAV-ITVTDTNDNPPIFNPTTYK 381
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNALF--MYTLFGEGKEMFDVD----ENTGVVK 847
G + EN + I +K TDAD + +YT+ + F V N G++K
Sbjct: 382 GQVPEN-EANVVI---TTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILK 437
Query: 848 FIGDSLDREKKIMYKL 863
LD E K Y L
Sbjct: 438 -TAKGLDFEAKQQYIL 452
Score = 47.6 bits (108), Expect = 0.003
Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
T+ L A N + I + D NDN PEF + + S++E G SV++V A
Sbjct: 227 TYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTA 286
Query: 331 TDKDQGENG-----EFTYQLDDP----KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKV 381
TD D N +T DP K F+I+ +G ++V T LDRE+ + + V
Sbjct: 287 TDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVT-TGLDRESFPTYTLVV 345
Query: 382 YAKETNPSVVGTFA 395
A + + T A
Sbjct: 346 QAADLQGEGLSTTA 359
Score = 45.2 bits (102), Expect = 0.014
Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA-LEVKRYFVINERHGHV-IVA 1004
GT+++++ A D D +N +N+ + + LS D L K F IN G + +V
Sbjct: 278 GTSVMEVTATDADDDVN-----TYNAAIAY--TILSQDPELPDKNMFTINRNTGVISVVT 330
Query: 1005 RSLPPES--EFRLNISALD--GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
L ES + L + A D G L+ + + V D ND+ P+F T Y V E +
Sbjct: 331 TGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENE-A 389
Query: 1061 RRVLGKVDATDADFGQNA--NLTYFIQPSD-TDLPFEISPLT--GVLSVNGELDRETEDK 1115
V+ + TDAD Y I D +P+ G+L LD E + +
Sbjct: 390 NVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQ 449
Query: 1116 YILTV 1120
YIL V
Sbjct: 450 YILHV 454
Score = 44.8 bits (101), Expect = 0.018
Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
Query: 810 NIIKATDADEGTNALFMYTLFGEGKE-----MFDVDENTGVVKFIGDSLDREKKIMYKLS 864
N+++ + +F Y++ G+G + +F ++ TG +K + + LDRE+ Y L
Sbjct: 174 NLVQIKSNKDKEGKVF-YSITGQGADTPPVGVFIIERETGWLK-VTEPLDRERIATYTLF 231
Query: 865 LVARDTGGLSSE--AELIIMIGDENDNKPEFNQ 895
A + G + E E++I + D+NDNKPEF Q
Sbjct: 232 SHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264
Score = 44.8 bits (101), Expect = 0.018
Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 8/125 (6%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V V DVN+ P+F V E + + A + D +TY I DT
Sbjct: 472 TVTVDVLDVNEA-PIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW-RDT 529
Query: 1090 DLPFEISPLTGVLSVNGELDRE-----TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
EI+P TG +S ELDRE Y ++A DNG DV
Sbjct: 530 ANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNG-SPVATGTGTLLLILSDV 588
Query: 1145 NDNSP 1149
NDN+P
Sbjct: 589 NDNAP 593
>UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadherin
gamma B5; n=2; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to protocadherin gamma B5 - Ornithorhynchus
anatinus
Length = 1443
Score = 87.4 bits (207), Expect = 3e-15
Identities = 105/477 (22%), Positives = 192/477 (40%), Gaps = 39/477 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQ 491
+E E ++ +V V + D NDN P F +++ + + +A G A DPD+G
Sbjct: 106 LEAVVENPLNVFHVNVEIQDINDNPPRFRRNHI-DLEISESAVSGASFALEPAQDPDVGI 164
Query: 492 NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSER 548
N + Y L N + + N + P+ + + L + A D +P
Sbjct: 165 NSLKNYLLSTNPNFSFDVKETKDGNKYAELIVGKPLDRETQNSYHLVLTAVDG-GDP--- 220
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
+ T+E+ + P F Y+ + ++ G+ V ++ D E +
Sbjct: 221 ---VLSGTVEIRINVTDANDNAPVFSQDVYKVSLRESLPPGSPVLRVEATDKDEGANARV 277
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAV-----ALQENANLSIVTNAT 663
V V + V ++S + + DFE + L+ +VT T
Sbjct: 278 TFAFS---NVAQTVRHAFALDPVSGEIS--TKGILDFEGIKGYSLVLEAKDGGGLVTQCT 332
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
V + ++ DE + + I + E+S + + T NG R +
Sbjct: 333 VEI-EILDENDNAPEVTFTSISSPIPEDSELGTVIALIRTRDRDSGDNGAVTCRI----E 387
Query: 724 QDVTDDIAIAEDG--TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
++ I + + + T LDRE+ Y +T+ A ++G +++ + D N
Sbjct: 388 GEIPFKIVSSSNNYYKLMTDSVLDREQTAEYNITITAT-DRGNPPLTTSKTISLLVADVN 446
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
DNPPVF H TY ++ EN++ G I + A+D D +NA Y+L + +
Sbjct: 447 DNPPVFPHTTYVAYVPENNRPGASIFR---VSASDRDLDSNARISYSLLDSSESELPLSS 503
Query: 842 NTGVVKFIGD-----SLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKP 891
+ + GD S D E+ ++L + A+D+G L + + + I D+NDN P
Sbjct: 504 SVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGSPPLRANVTVRVFIVDQNDNAP 560
Score = 83.8 bits (198), Expect = 3e-14
Identities = 122/528 (23%), Positives = 219/528 (41%), Gaps = 49/528 (9%)
Query: 379 MKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQ 438
+K Y TNP+ +++ K+ L PL++ T V T + D
Sbjct: 167 LKNYLLSTNPNFSFDVKETKDGNKYAE--LIVGKPLDRETQNSYHLVLTAVDG---GDPV 221
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V + + + DANDN PVF ++Y+ S++ + G+ + +V+A D D G N V +
Sbjct: 222 LSGTVEIRINVTDANDNAPVF-SQDVYKVSLRESLPPGSPVLRVEATDKDEGANARVTFA 280
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVT 556
+ T+ F ++P +G +S EG ++L +EA D ++ V
Sbjct: 281 FSNVAQ-TVRHAFALDPVSGEISTKGILDFEGIKGYSLVLEAKDGGGLVTQ-----CTVE 334
Query: 557 IEVTRGTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
IE+ N P++ + +P + + +GT + IR D + D + + E
Sbjct: 335 IEIL-DENDNAPEVTFTSISSP----IPEDSELGTVIALIRTRDR-DSGD-NGAVTCRIE 387
Query: 616 EGVPF-AVEERSGVITVVDD--LSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDVN 670
+PF V + ++ D L R Y+ + + N + T+ T+ V DVN
Sbjct: 388 GEIPFKIVSSSNNYYKLMTDSVLDREQTAEYNI-TITATDRGNPPLTTSKTISLLVADVN 446
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQD----V 726
D V H+ + +V EN+ A IF + S + + + + + + +
Sbjct: 447 DNPPVF---PHTTYVAYVPENNRPGA--SIFRVSASDRDLDSNARISYSLLDSSESELPL 501
Query: 727 TDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPP 785
+ ++I + G I+ Q+ D E+ + + V A+ + A + V ++I D+NDN P
Sbjct: 502 SSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGSPPLRANV-TVRVFIVDQNDNAP 560
Query: 786 VFEHATYEG-----FIMENSKIGTEIKMDNIIKATDADEGTNALFMY-TLFGEGKEMFDV 839
+ E F M + ++ A DAD G NA Y L +F +
Sbjct: 561 RILYPALEPDGSALFDMVPRSAEPGYLVSKVV-AVDADSGPNAWLAYHVLQASDPGLFSL 619
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGD 885
TG ++ D + ++L + RD G LSS L ++ D
Sbjct: 620 GLRTGEIRTARALADGDPS-RHRLLVAVRDGGQPPLSSTVALHLVFAD 666
Score = 82.6 bits (195), Expect = 8e-14
Identities = 105/417 (25%), Positives = 182/417 (43%), Gaps = 43/417 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
I E+ G + A D D G+N Y ++ S D E K ++
Sbjct: 142 ISESAVSGASFALEPAQDPDVGINSLKNYLLSTN-----PNFSFDVKETKD----GNKYA 192
Query: 1000 HVIVARSLPPESE--FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+IV + L E++ + L ++A+DGG+ L+ + +R+ V D ND+ PVF + Y ++
Sbjct: 193 ELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQDVYKVSLR 252
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDT-DLPFEISPLTGVLSVNGELDRETE 1113
E+ + +V+ATD D G NA +T+ F + T F + P++G +S G LD E
Sbjct: 253 ESLPPGSPVLRVEATDKDEGANARVTFAFSNVAQTVRHAFALDPVSGEISTKGILDFEGI 312
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNF 1173
Y L + A+D G D NDN+P+ F + PE EL
Sbjct: 313 KGYSLVLEAKDGG---GLVTQCTVEIEILDENDNAPE-VTFTSISS-PIPEDSELGT--- 364
Query: 1174 ESVMMIPVYKATIEENAPIGTTV-AKVFANDTDFIGNGNGLILYSLPQRKN--QQNL--- 1227
+ +I +N + + ++ N L+ S+ R+ + N+
Sbjct: 365 -VIALIRTRDRDSGDNGAVTCRIEGEIPFKIVSSSNNYYKLMTDSVLDREQTAEYNITIT 423
Query: 1228 ----GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNL 1281
G P L+++ + + VADV D + PVF Y + EN A + VS +
Sbjct: 424 ATDRGNPPLTTSKTISLLVADVND-----NPPVFPHTTYVAYVPENNRPGASIFRVSASD 478
Query: 1282 TEHYENFKMRYYIL--NENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAE 1336
+ N ++ Y +L +E++ + + I+ +G +Y RS D E +E+ V+A+
Sbjct: 479 RDLDSNARISYSLLDSSESELPLSSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQ 535
Score = 81.4 bits (192), Expect = 2e-13
Identities = 85/329 (25%), Positives = 140/329 (42%), Gaps = 21/329 (6%)
Query: 574 MGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVD 633
+G + + + G+ VG + + +VS L E F V SG + V
Sbjct: 29 LGEQIRYSIPEEMAKGSVVGHLARDLGLNIREVSGRKLRVSAEKQLFTVSADSGDLLVSH 88
Query: 634 DLSRYNRPMYDFEAVALQENA--NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN 691
+ R L E N V + V + D+ND + + I + E+
Sbjct: 89 RIDREQICGKTVRCSILLEAVVENPLNVFHVNVEIQDINDNPP---RFRRNHIDLEISES 145
Query: 692 SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQ----KPLDRE 747
+ A + + N N +L++ + + D+ +DG + + KPLDRE
Sbjct: 146 AVSGASFALEPAQDPDVGINSLKN--YLLSTNPNFSFDVKETKDGNKYAELIVGKPLDRE 203
Query: 748 KRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEI 806
++ Y + + A + V+SG ++ I + D NDN PVF Y+ + E+ G+ +
Sbjct: 204 TQNSYHLVLTAVDGGDPVLSGT--VEIRINVTDANDNAPVFSQDVYKVSLRESLPPGSPV 261
Query: 807 KMDNIIKATDADEGTNALFMYTLFGEGKEM---FDVDENTGVVKFIGDSLDREKKIMYKL 863
++ATD DEG NA + + + F +D +G + G LD E Y L
Sbjct: 262 LR---VEATDKDEGANARVTFAFSNVAQTVRHAFALDPVSGEISTKG-ILDFEGIKGYSL 317
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPE 892
L A+D GGL ++ + I I DENDN PE
Sbjct: 318 VLEAKDGGGLVTQCTVEIEILDENDNAPE 346
Score = 79.8 bits (188), Expect = 5e-13
Identities = 52/171 (30%), Positives = 89/171 (52%), Gaps = 9/171 (5%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSL-DSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
A D D+G+ + Y L+S N F + ++ +G+ + E + + Q N++ L + A
Sbjct: 157 AQDPDVGINSLKNY-LLSTNPNFSFDVKETKDGNKYAELIVGKPLDRETQ-NSYHLVLTA 214
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+P+ + + I + D NDN P F D Y +S+ E+LP G VL+V ATDKD+G N
Sbjct: 215 VDGGDPVLSGTVEIRINVTDANDNAPVFSQDVYKVSLRESLPPGSPVLRVEATDKDEGAN 274
Query: 339 GEFTYQLDD----PKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
T+ + + AF++DP SG ++ + +LD E + + AK+
Sbjct: 275 ARVTFAFSNVAQTVRHAFALDPVSGEISTKG--ILDFEGIKGYSLVLEAKD 323
Score = 69.7 bits (163), Expect = 6e-10
Identities = 55/171 (32%), Positives = 79/171 (46%), Gaps = 13/171 (7%)
Query: 733 AEDGTIFTQKPLDREK--RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
A+ G + +DRE+ R +++ E V + ++ V + I+D NDNPP F
Sbjct: 79 ADSGDLLVSHRIDREQICGKTVRCSILLE--AVVENPLNVFHVNVEIQDINDNPPRFRRN 136
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF-- 848
+ I E++ G ++ A D D G N+L Y L FDV E K+
Sbjct: 137 HIDLEISESAVSGASFALE---PAQDPDVGINSLKNYLLSTNPNFSFDVKETKDGNKYAE 193
Query: 849 --IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+G LDRE + Y L L A D G LS E+ I + D NDN P F+Q
Sbjct: 194 LIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQ 244
Score = 69.3 bits (162), Expect = 8e-10
Identities = 65/239 (27%), Positives = 106/239 (44%), Gaps = 19/239 (7%)
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPP 978
IE+ +N A +V IPE+ +GT I + D DSG NG + E+ P
Sbjct: 335 IEILDENDNAPEVTFTSISSPIPEDSELGTVIALIRTRDRDSGDNGAVTCRIEGEI---P 391
Query: 979 SKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVK 1036
K+ + + Y+ + ++ R +E+ + I+A D GN L + ++ + V
Sbjct: 392 FKIVSSS---NNYYKLMTDS---VLDRE--QTAEYNITITATDRGNPPLTTSKTISLLVA 443
Query: 1037 DVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLPF-- 1093
DVND+ PVF T Y V E + +V A+D D NA ++Y + S+++LP
Sbjct: 444 DVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDLDSNARISYSLLDSSESELPLSS 503
Query: 1094 --EISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
I+ +G + D E + L V A+D+G D NDN+P+
Sbjct: 504 SVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSG-SPPLRANVTVRVFIVDQNDNAPR 561
Score = 66.5 bits (155), Expect = 5e-09
Identities = 63/246 (25%), Positives = 111/246 (45%), Gaps = 20/246 (8%)
Query: 218 IHAIDQDLGVGA--TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D+D G A T + ++ R F+LD V+G + + LD + ++ + VL+
Sbjct: 264 VEATDKDEGANARVTFAFSNVAQTVRHAFALDPVSGEISTKGILDFEG---IKGYSLVLE 320
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
+ L T Q VEIE+LD NDN PE + I E+ G + + D+D
Sbjct: 321 AKDG---GGLVT-QCTVEIEILDENDNAPEVTFTSISSPIPEDSELGTVIALIRTRDRDS 376
Query: 336 GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTF 394
G+NG T +++ + + + + +VLDRE + + + A + NP + +
Sbjct: 377 GDNGAVTCRIEGEIPFKIVSSSNNYYKLMTDSVLDREQTAEYNITITATDRGNPPLTTSK 436
Query: 395 ADSQRIAKWRRQPLETNAPL-EKTTYV--FPD--KVGTKTENIEYYDEQLMSFVNVEVTL 449
S +A + N P+ TTYV P+ + G + D L S + +L
Sbjct: 437 TISLLVA-----DVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDLDSNARISYSL 491
Query: 450 LDANDN 455
LD++++
Sbjct: 492 LDSSES 497
Score = 63.3 bits (147), Expect = 5e-08
Identities = 66/244 (27%), Positives = 106/244 (43%), Gaps = 19/244 (7%)
Query: 656 LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGTG 714
LS ++V D ND V + + ++E+ G+ + ++ T+
Sbjct: 222 LSGTVEIRINVTDANDNAPVFSQDVYK---VSLRESLPPGSPVLRVEATDKDE---GANA 275
Query: 715 NVRFLIAN-QQDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQ 772
V F +N Q V A+ G I T+ LD E Y + + A+ G+++
Sbjct: 276 RVTFAFSNVAQTVRHAFALDPVSGEISTKGILDFEGIKGYSLVLEAKDGGGLVTQC---T 332
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE 832
V I I DENDN P + I E+S++GT I + I+ D D G N + GE
Sbjct: 333 VEIEILDENDNAPEVTFTSISSPIPEDSELGTVIAL---IRTRDRDSGDNGAVTCRIEGE 389
Query: 833 GKEMFDVDENTGVVKFIGDS-LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDN 889
V + K + DS LDRE+ Y +++ A D G L++ + +++ D NDN
Sbjct: 390 IPFKI-VSSSNNYYKLMTDSVLDREQTAEYNITITATDRGNPPLTTSKTISLLVADVNDN 448
Query: 890 KPEF 893
P F
Sbjct: 449 PPVF 452
Score = 59.7 bits (138), Expect = 6e-07
Identities = 59/199 (29%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PEN G +I +++A D D N +I Y S L + IN G
Sbjct: 461 VPENNRPGASIFRVSASDRDLDSNARISYSLLDS--------SESELPLSSSVSINSHSG 512
Query: 1000 HVIVARSLPPES--EFRLNISALDGGN--LNDNISVRVFVKDVNDH-----FPVFKKTWY 1050
+ RS E F L++ A D G+ L N++VRVF+ D ND+ +P +
Sbjct: 513 DIYAQRSFDYEQFRAFELHVQAQDSGSPPLRANVTVRVFIVDQNDNAPRILYPALEPDGS 572
Query: 1051 NF--NVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGE 1107
V + ++ KV A DAD G NA L Y + Q SD L F + TG +
Sbjct: 573 ALFDMVPRSAEPGYLVSKVVAVDADSGPNAWLAYHVLQASDPGL-FSLGLRTGEIRTARA 631
Query: 1108 LDRETEDKYILTVVARDNG 1126
L ++ L V RD G
Sbjct: 632 LADGDPSRHRLLVAVRDGG 650
Score = 55.2 bits (127), Expect = 1e-05
Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 21/157 (13%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKL-----FSLDSVNGSLFLEKELDLDAEHNLQANTF 272
+ A D+DL A + Y L+ ++ +L S++S +G ++ ++ D + Q F
Sbjct: 474 VSASDRDLDSNARISYSLLDSSESELPLSSSVSINSHSGDIYAQRSFDYE-----QFRAF 528
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF---EVDFYNISIVENLPN----GFSV 325
L VQA +P A V + ++D NDN P ++ ++ + +P G+ V
Sbjct: 529 ELHVQAQDSGSPPLRANVTVRVFIVDQNDNAPRILYPALEPDGSALFDMVPRSAEPGYLV 588
Query: 326 LQVMATDKDQGENGEFTY---QLDDPKGAFSIDPRSG 359
+V+A D D G N Y Q DP G FS+ R+G
Sbjct: 589 SKVVAVDADSGPNAWLAYHVLQASDP-GLFSLGLRTG 624
Score = 52.4 bits (120), Expect = 9e-05
Identities = 41/122 (33%), Positives = 59/122 (48%), Gaps = 14/122 (11%)
Query: 773 VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-G 831
V++ + D NDN P F ++E F+ EN++ G + + A+D D G N L Y+L
Sbjct: 1031 VSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCS---LAASDPDSGLNGLIAYSLLEP 1087
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
G+E TG V S D E+ + + ARD G LSS + + I D NDN
Sbjct: 1088 RGRE-------TGAV-HAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRLFILDVNDN 1139
Query: 890 KP 891
P
Sbjct: 1140 AP 1141
Score = 47.6 bits (108), Expect = 0.003
Identities = 24/74 (32%), Positives = 38/74 (51%)
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
Q S +P ++Q V + + D+NDN P F + + + EN G + + A+D D G
Sbjct: 1016 QRSTAGSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSG 1075
Query: 337 ENGEFTYQLDDPKG 350
NG Y L +P+G
Sbjct: 1076 LNGLIAYSLLEPRG 1089
Score = 46.8 bits (106), Expect = 0.005
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 1031 VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTD 1090
V V ++D+ND+ P F++ + + E+ + A D D G N+ Y + ++ +
Sbjct: 119 VNVEIQDINDNPPRFRRNHIDLEISESAVSGASFALEPAQDPDVGINSLKNYLLS-TNPN 177
Query: 1091 LPFEISPLT-----GVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
F++ L V LDRET++ Y L + A D G D N
Sbjct: 178 FSFDVKETKDGNKYAELIVGKPLDRETQNSYHLVLTAVDGG-DPVLSGTVEIRINVTDAN 236
Query: 1146 DNSPKF 1151
DN+P F
Sbjct: 237 DNAPVF 242
Score = 45.6 bits (103), Expect = 0.011
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
Query: 240 DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDL 299
+++LF++ + +G L + +D + +L + + NPL VEI+ D+
Sbjct: 71 EKQLFTVSADSGDLLVSHRIDREQICGKTVRCSILL--EAVVENPLNVFHVNVEIQ--DI 126
Query: 300 NDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGAFSI-DPR 357
NDN P F + ++ I E+ +G S A D D G N Y L +P +F + + +
Sbjct: 127 NDNPPRFRRNHIDLEISESAVSGASFALEPAQDPDVGINSLKNYLLSTNPNFSFDVKETK 186
Query: 358 SG--WLTVRNQTVLDREAHSSLRMKVYAKE-TNPSVVGT 393
G + + LDRE +S + + A + +P + GT
Sbjct: 187 DGNKYAELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGT 225
Score = 41.9 bits (94), Expect = 0.13
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFV-----PSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNG 493
L S V V + +LD NDN P + P L ++ +A G ++ KV AVD D G N
Sbjct: 1123 LSSTVTVRLFILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNA 1182
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQP 542
V Y L + T+ + + T + + R + V+ S P
Sbjct: 1183 WVSYQLFEAPDPTLFAVSRYAGEIRTAGPIPADLPPQRLVIMVQDSGNP 1231
Score = 41.1 bits (92), Expect = 0.23
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V + + D NDN P F + +E ++ N + G ++ + A DPD G NG++ Y
Sbjct: 1025 LSSQRTVSLNVSDVNDNAPAFFRRS-HEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYS 1083
Query: 499 L 499
L
Sbjct: 1084 L 1084
Score = 41.1 bits (92), Expect = 0.23
Identities = 46/195 (23%), Positives = 77/195 (39%), Gaps = 27/195 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN G + L A D DSGLNG I Y + P A+ R F +
Sbjct: 1054 VQENNRPGVLLCSLAASDPDSGLNGLIAYSL-----LEPRGRETGAVHAARSFDYEQTQ- 1107
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN---- 1053
+ + A D G L+ ++VR+F+ DVND+ P +
Sbjct: 1108 ------------TLQFEVQARDRGEPPLSSTVTVRLFILDVNDNAPAVLRPQARPGALCP 1155
Query: 1054 --VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
+ + ++ KV A D D G NA ++Y + + F +S G + G + +
Sbjct: 1156 QALPPSASAGHLVTKVTAVDLDSGYNAWVSYQLFEAPDPTLFAVSRYAGEIRTAGPIPAD 1215
Query: 1112 TEDKYILTVVARDNG 1126
+ L ++ +D+G
Sbjct: 1216 LPPQR-LVIMVQDSG 1229
Score = 37.9 bits (84), Expect = 2.1
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 10/126 (7%)
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY-F 1083
L+ +V + V DVND+ P F + + V+E +L + A+D D G N + Y
Sbjct: 1025 LSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYSL 1084
Query: 1084 IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXD 1143
++P + TG + D E V ARD G D
Sbjct: 1085 LEPRGRE--------TGAVHAARSFDYEQTQTLQFEVQARDRG-EPPLSSTVTVRLFILD 1135
Query: 1144 VNDNSP 1149
VNDN+P
Sbjct: 1136 VNDNAP 1141
>UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens
"Protocadherin LKC precursor; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Protocadherin LKC
precursor - Takifugu rubripes
Length = 1174
Score = 87.4 bits (207), Expect = 3e-15
Identities = 163/731 (22%), Positives = 289/731 (39%), Gaps = 75/731 (10%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
++A DQD G+ + Y + LF + S +G + + +D + + T
Sbjct: 214 VNAFDQDKGINDAIIYSIEGSTTEGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATES 273
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEF-EVDFYNISIV----ENLPNGFSVLQVMATD 332
++ +V+I + D+NDN PEF + FY ++ E L + + + T
Sbjct: 274 KQDVHGVFANTTVQVQINIQDVNDNGPEFYKCGFYCVNTSHFTGEVLEHFLGSISINMTV 333
Query: 333 KDQGENGEFTY-QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVV 391
KD T + +PK + T R Q +L+ E V++ + V
Sbjct: 334 KDPDRVSRSTITRTPEPKVWLRVTLTIFPKTPRTQLILEGEDKD-----VFSVQPESLVS 388
Query: 392 GTFADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLD 451
G Q +QP + Y ++ K I+ + + S V ++++D
Sbjct: 389 GINVQLQV-----KQP-------QNLDYEVKQQMILKVVAIDEGESKFRSTATVTISIID 436
Query: 452 ANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPF 511
NDN+P F P + Y+ S+ +A G VI + A DPD G + Y L S I F
Sbjct: 437 TNDNSPKF-PKDTYKLSVPEHASNGMVIANITAEDPDTMDRGNIRYRLLPDS---ILQYF 492
Query: 512 KINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIP 571
++ TG V V S +L+ R + + A SE + + I VT P
Sbjct: 493 GVDNRTGAVFVKNSTLLD-REVRSLHSVTLQARDSEDKTGSTELEITVT----DINDQYP 547
Query: 572 DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGV---PFAVEERSGV 628
Y+ +V G +I DA N ++ +++ F ++ SGV
Sbjct: 548 VINRDSYQVFVKEG---GDFNLKIEATDADMPNTLNSQIVYAISPSTYSDNFTIDPNSGV 604
Query: 629 ITVVDDLSRY---NRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+T +L R ++ E V + + +N TV +V++ D + + +++
Sbjct: 605 LTNSGNLDREFLDSKLQGRVELIVTATDKGTPPLSSNVTV-IVNIEDINDNIPQFSNASY 663
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI-AIAED-----GTI 738
F VKE GA +G ++ ++ + F I + + I + AED G I
Sbjct: 664 TFSVKEGQKGAYVGSVYAEDLDQT--TEFNRISFSIVDGSSGSFIIRSFAEDGRGYRGDI 721
Query: 739 FTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
++ + + T+ E + + V + + D ND P E E ++
Sbjct: 722 RVDPDVELDYESIRNQTLRIE-AADLEQRSAEAVVKVNVLDVNDERP--EFGPIEPVSVK 778
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD--------VDENTGVVKF-I 849
+ TE + K T D N +Y L + D + + TG V+
Sbjct: 779 ENTNNTE----TVGKFTAYDRDGNHSLLYELESIQCKCNDSMTSCNSFILDTTGEVRVNP 834
Query: 850 GDSLDREK--KIMYKLSLVARDT-GGLSSEAE---LIIMIGDENDNKPEFNQIEENSKVR 903
D +D EK +++ + +V + T G ++ A+ ++I I D NDN PEF I +S
Sbjct: 835 NDLVDYEKCDQVLIEAQVVDQFTEKGENNSAKTGLMVINIEDVNDNAPEF--IYSDSVFV 892
Query: 904 IHRETKLNGTA 914
+ E+ GT+
Sbjct: 893 VVSESASKGTS 903
Score = 79.8 bits (188), Expect = 5e-13
Identities = 78/259 (30%), Positives = 111/259 (42%), Gaps = 35/259 (13%)
Query: 907 ETKLNGTAGFTIIEVKPKN---KFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLN 963
E+K TA TI + + KF D +L +PE+ G I + A D D+
Sbjct: 421 ESKFRSTATVTISIIDTNDNSPKFPKDTYKLS----VPEHASNGMVIANITAEDPDTMDR 476
Query: 964 GQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR----LNISA 1019
G IRY +P S L +YF ++ R G V V S + E R + + A
Sbjct: 477 GNIRYRL-----LPDSIL--------QYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQA 523
Query: 1020 LDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQ--N 1077
D + + + + V D+ND +PV + Y V+E K++ATDAD N
Sbjct: 524 RDSEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEGGDFNL---KIEATDADMPNTLN 580
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYI-----LTVVARDNGXXXXXX 1132
+ + Y I PS F I P +GVL+ +G LDRE D + L V A D G
Sbjct: 581 SQIVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTATDKG-TPPLS 639
Query: 1133 XXXXXXXXXXDVNDNSPKF 1151
D+NDN P+F
Sbjct: 640 SNVTVIVNIEDINDNIPQF 658
Score = 72.5 bits (170), Expect = 8e-11
Identities = 100/343 (29%), Positives = 146/343 (42%), Gaps = 53/343 (15%)
Query: 816 DADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
DA + N + L G F V++ TG V FI +LDRE I Y G
Sbjct: 8 DASDPENDPLTFELIGPNSGFFSVEQGTGRV-FIDQTLDREWIIYYVC-------GVFQI 59
Query: 876 EAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLG 935
+ +L I + + NDNKP F Q ++K T + G ++ +++ D+ G
Sbjct: 60 QRDLTIFLKEANDNKPIFQQSSYDTK------TPEDTAVGASLFTALAEDR---DLSNAG 110
Query: 936 PL-FLIPENIP-IGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
+ + I E IP G + ++NA + LNG + Y S Y ++K
Sbjct: 111 AVRYSIDEVIPSSGVNLFRINASGV-VWLNGSLNYNTLSTFY-----------QLK---- 154
Query: 994 INERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
IN G R E+ F N+ + I++ V V D+N P+F Y +
Sbjct: 155 INATDGG---GRCFYNETNFWSNV-------VFSFITI-VDVPDLN---PMFLGLPYVAS 200
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE-T 1112
VEE + V+A D D G N + Y I+ S T+ F+IS GV+SV G +DRE T
Sbjct: 201 VEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEGLFKISSDDGVISVAGPIDREVT 260
Query: 1113 EDKYILTVVA---RDNGXXXXXXXXXXXXXXXXDVNDNSPKFY 1152
D LTV A + + DVNDN P+FY
Sbjct: 261 GDTVNLTVKATESKQDVHGVFANTTVQVQINIQDVNDNGPEFY 303
Score = 63.3 bits (147), Expect = 5e-08
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 10/228 (4%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIG 803
LD E + + V+A ++G VTI I D NDN P F TY+ + E++ G
Sbjct: 402 LDYEVKQQMILKVVA-IDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNG 460
Query: 804 TEIKMDNIIKATDADEGTNALFMYTLFGEG-KEMFDVDENTGVVKFIGDS--LDREKKIM 860
I I A D D Y L + + F VD TG V F+ +S LDRE + +
Sbjct: 461 MVIAN---ITAEDPDTMDRGNIRYRLLPDSILQYFGVDNRTGAV-FVKNSTLLDREVRSL 516
Query: 861 YKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRE--TKLNGTAGFTI 918
+ ++L ARD+ + EL I + D ND P N+ V+ + K+ T
Sbjct: 517 HSVTLQARDSEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEGGDFNLKIEATDADMP 576
Query: 919 IEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQI 966
+ + +A+ F I N + T L+ LDS L G++
Sbjct: 577 NTLNSQIVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRV 624
Score = 53.6 bits (123), Expect = 4e-05
Identities = 91/387 (23%), Positives = 148/387 (38%), Gaps = 50/387 (12%)
Query: 1015 LNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L + A+D G +V + + D ND+ P F K Y +V E V+ + A D
Sbjct: 412 LKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNGMVIANITAEDP 471
Query: 1073 DFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE--LDRETEDKYILTVVARDNGXXXX 1130
D N+ Y + P F + TG + V LDRE + +T+ ARD+
Sbjct: 472 DTMDRGNIRYRLLPDSILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQARDS---ED 528
Query: 1131 XXXXXXXXXXXXDVNDNSP-----KFYAF-----DELLEWKHPEADELSNHNFESVMMI- 1179
D+ND P + F D L+ + +AD + N + V I
Sbjct: 529 KTGSTELEITVTDINDQYPVINRDSYQVFVKEGGDFNLKIEATDADMPNTLNSQIVYAIS 588
Query: 1180 -PVY--KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGLPSLSSTA 1236
Y TI+ N+ + T + D G ++ + + G P LSS
Sbjct: 589 PSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTATDK------GTPPLSSNV 642
Query: 1237 ILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPV--ELVSLNLTEHYENFKMRYYI 1294
++V + D+ D + P F + Y ++E + + +L + E ++ + I
Sbjct: 643 TVIVNIEDINDNI-----PQFSNASYTFSVKEGQKGAYVGSVYAEDLDQTTEFNRISFSI 697
Query: 1295 LN-ENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAE 1353
++ + + I R+F D R + PD E+ YE I Q E + AE
Sbjct: 698 VDGSSGSFIIRSFAEDGRGYRGDIRVDPDVEL--DYESI---RNQTLRIEAADLEQRSAE 752
Query: 1354 DVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
V V V + DVND P+F
Sbjct: 753 AV----------VKVNVLDVNDERPEF 769
Score = 46.4 bits (105), Expect = 0.006
Identities = 37/123 (30%), Positives = 57/123 (46%), Gaps = 5/123 (4%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD--DPKGA 351
I ++D+ D P F Y S+ EN P SV V A D+D+G N Y ++ +G
Sbjct: 180 ITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEGL 239
Query: 352 FSIDPRSGWLTVRNQTVLDRE-AHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLET 410
F I G ++V +DRE ++ + V A E+ V G FA++ + Q +
Sbjct: 240 FKISSDDGVISVAGP--IDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQINIQDVND 297
Query: 411 NAP 413
N P
Sbjct: 298 NGP 300
Score = 46.0 bits (104), Expect = 0.008
Identities = 55/202 (27%), Positives = 88/202 (43%), Gaps = 14/202 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + L +ANDN P+F S+ Y+ + VG + A D DL G V Y +
Sbjct: 62 DLTIFLKEANDNKPIFQQSS-YDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSIDEVI 120
Query: 504 NLTITSPFKINPNTGTVSVAES---PILEGRHALFVEASDQPAN--PSERRYSLAVVTIE 558
+ + F+IN +G V + S L + L + A+D +E + VV
Sbjct: 121 PSSGVNLFRINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNFWSNVVFSF 179
Query: 559 VTRGTKGNKPDI-PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ-ND-VSYDLLHGYE 615
+ T + PD+ P F+G PY V N + SV + D + ND + Y +
Sbjct: 180 I---TIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTT 236
Query: 616 EGVPFAVEERSGVITVVDDLSR 637
EG+ F + GVI+V + R
Sbjct: 237 EGL-FKISSDDGVISVAGPIDR 257
Score = 44.8 bits (101), Expect = 0.018
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 14/144 (9%)
Query: 929 LDVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
+DV L P+FL + EN P+ ++ +NA D D G+N I Y K+
Sbjct: 183 VDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEGLFKI 242
Query: 982 SADALEVKRYFVIN-ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVND 1040
S+D + I+ E G + ES+ + G N + V++ ++DVND
Sbjct: 243 SSDDGVISVAGPIDREVTGDTVNLTVKATESK-----QDVHGVFANTTVQVQINIQDVND 297
Query: 1041 HFPVFKKTWYNFNVEEAQYTRRVL 1064
+ P F K + + V + +T VL
Sbjct: 298 NGPEFYKCGF-YCVNTSHFTGEVL 320
Score = 44.4 bits (100), Expect = 0.024
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK 834
I I D D P+F Y + ENS + + N A D D+G N +Y++ G
Sbjct: 180 ITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVN---AFDQDKGINDAIIYSIEGSTT 236
Query: 835 E-MFDVDENTGVVKFIGDSLDREK-----KIMYKLSLVARDTGGL--SSEAELIIMIGDE 886
E +F + + GV+ G +DRE + K + +D G+ ++ ++ I I D
Sbjct: 237 EGLFKISSDDGVISVAGP-IDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQINIQDV 295
Query: 887 NDNKPEF 893
NDN PEF
Sbjct: 296 NDNGPEF 302
Score = 42.3 bits (95), Expect = 0.099
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 23/133 (17%)
Query: 951 IKLNALDLD--SGLNGQIRYEFNSEVYI------PPSKLSADALEVKRYFVINERHGHVI 1002
+K+ A D D + LN QI Y + Y P S + ++ + R F+ ++ G V
Sbjct: 566 LKIEATDADMPNTLNSQIVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRV- 624
Query: 1003 VARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYT 1060
L ++A D G L+ N++V V ++D+ND+ P F Y F+V+E Q
Sbjct: 625 -----------ELIVTATDKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSVKEGQKG 673
Query: 1061 RRVLGKVDATDAD 1073
V G V A D D
Sbjct: 674 AYV-GSVYAEDLD 685
Score = 41.9 bits (94), Expect = 0.13
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEV-DFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
NN KT + IE D+NDN PEF D + + E+ G SV V ATD+D G N +
Sbjct: 862 NNSAKTGLMVINIE--DVNDNAPEFIYSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQ 919
Query: 341 FTYQL 345
+++
Sbjct: 920 MEFKV 924
Score = 40.3 bits (90), Expect = 0.40
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 20/149 (13%)
Query: 1233 SSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRY 1292
S+ +T+ DVPD P+F+ Y +EEN + ++N + +
Sbjct: 173 SNVVFSFITIVDVPDL-----NPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAI 227
Query: 1293 YILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK-DTYEVIVRAERQKYSRELPHMIYPV 1351
E T F I +G + + DREV DT + V+A K
Sbjct: 228 IYSIEGSTT-EGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATESK------------ 274
Query: 1352 AEDVLEGMTKYDVKVVVRIKDVNDNSPKF 1380
+DV V+V + I+DVNDN P+F
Sbjct: 275 -QDVHGVFANTTVQVQINIQDVNDNGPEF 302
Score = 37.9 bits (84), Expect = 2.1
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 25/191 (13%)
Query: 423 DKVGTKTENIEYYD-EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
+ + +T IE D EQ + V+V +LD ND P F P + S+K N +GK
Sbjct: 732 ESIRNQTLRIEAADLEQRSAEAVVKVNVLDVNDERPEFGP--IEPVSVKENTNNTETVGK 789
Query: 482 VKAVDPDLGQNGMVLYDLQR-----TSNLTITSPFKINPNTGTVSVAESPIL--EGRHAL 534
A D D N +LY+L+ ++T + F I TG V V + ++ E +
Sbjct: 790 FTAYDRD--GNHSLLYELESIQCKCNDSMTSCNSF-ILDTTGEVRVNPNDLVDYEKCDQV 846
Query: 535 FVEAS--DQPANPSER---RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGS-NVGI 588
+EA DQ E + L V+ IE + P+F+ + F V S +
Sbjct: 847 LIEAQVVDQFTEKGENNSAKTGLMVINIEDV------NDNAPEFIYSDSVFVVVSESASK 900
Query: 589 GTSVGQIRVND 599
GTSV + D
Sbjct: 901 GTSVAGVTATD 911
Score = 37.5 bits (83), Expect = 2.8
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 15/117 (12%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
L +ELI N FS++ G +F+++ LD E + V Q+Q
Sbjct: 17 LTFELIGPNSG-FFSVEQGTGRVFIDQTLD--REWIIYYVCGVFQIQRD----------- 62
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDD 347
+ I L + NDN P F+ Y+ E+ G S+ +A D+D G Y +D+
Sbjct: 63 -LTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSIDE 118
Score = 37.5 bits (83), Expect = 2.8
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 12/112 (10%)
Query: 769 GIYQV----TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL 824
G++Q+ TI++++ NDN P+F+ ++Y+ E++ +G + A D D
Sbjct: 55 GVFQIQRDLTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASL---FTALAEDRDLSNAGA 111
Query: 825 FMYTLF----GEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG 872
Y++ G +F ++ +GVV G Y+L + A D GG
Sbjct: 112 VRYSIDEVIPSSGVNLFRINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGG 162
>UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF15040, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 839
Score = 87.0 bits (206), Expect = 3e-15
Identities = 107/414 (25%), Positives = 174/414 (42%), Gaps = 54/414 (13%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALD---GGNLNDNISVRVFVKDVNDHFPVFK 1046
F+I+E +G + R L E + + L + ++ G L + + D+ND+ P F
Sbjct: 70 FIIDENNGDLHATRRLDREEKAYYILKATVVNKRTGQKLEPETEFTIKLHDINDNEPHFS 129
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
+ Y +V E + +V ATDAD +G +A L Y I S F + P TGV+
Sbjct: 130 QEVYTGSVPERSDIGTSVIQVTATDADDGMYGNSAKLVYSI--SQGHPYFSVDPNTGVIR 187
Query: 1104 V---NGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
G++DRE + Y + + A+D G DVNDN P+F + +
Sbjct: 188 TALGPGDMDREQREHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRF--TQSIYQ 245
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFI----GNGNGLIL 1215
++ PE+ E V I I ENA + T+ DT I G+I
Sbjct: 246 FRVPESSESGT----PVGRIRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVIT 301
Query: 1216 YSLP---QRK-------NQQNLGL-PSLSSTAILMVTVADVPDEVEMSDKPVFISRYYEL 1264
S P ++K QN + P S V + E ++ + P+F Y +
Sbjct: 302 VSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAVE-DVDEPPLFDKASYLM 360
Query: 1265 EIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDRE 1324
E++E+ V L S++ + + Y ++ TD+ F + P NG+++L++S DRE
Sbjct: 361 EVKEDAAVGVALGSVSAIDPDGARNIVKYAIDRR-TDMDHLFNVHPGNGSVFLLKSLDRE 419
Query: 1325 VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
+ + V A SR+ H V V + + DVNDN+P
Sbjct: 420 ESAWHNISVIATELHNSRQSSH-----------------VPVFIHLLDVNDNAP 456
Score = 85.0 bits (201), Expect = 1e-14
Identities = 64/219 (29%), Positives = 105/219 (47%), Gaps = 15/219 (6%)
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
F ++E G+ I +GNG V+++++ + I +G + + LD
Sbjct: 29 FFLQEEYTGSDYQYIGKLQSDQDHGNGL--VKYVLSGEGAGNIFIIDENNGDLHATRRLD 86
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE++ Y + + + TI + D NDN P F Y G + E S IGT
Sbjct: 87 REEKAYYILKATVVNKRTGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTS 146
Query: 806 IKMDNIIKATDADE---GTNALFMYTLFGEGKEMFDVDENTGVVK-FIG-DSLDREKKIM 860
+ + ATDAD+ G +A +Y++ +G F VD NTGV++ +G +DRE++
Sbjct: 147 VIQ---VTATDADDGMYGNSAKLVYSI-SQGHPYFSVDPNTGVIRTALGPGDMDREQREH 202
Query: 861 YKLSLVARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
Y++ + A+D GGL+ + I + D NDN P F Q
Sbjct: 203 YQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQ 241
Score = 81.8 bits (193), Expect = 1e-13
Identities = 74/288 (25%), Positives = 131/288 (45%), Gaps = 16/288 (5%)
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
+G+++ + V Y +L G G F ++E +G + L R + Y +A +
Sbjct: 43 IGKLQSDQDHGNGLVKY-VLSGEGAGNIFIIDENNGDLHATRRLDREEKAYYILKATVVN 101
Query: 652 ENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-I 708
+ L T T+ + D+ND + ++ + + + G ++ Q+ T+ +
Sbjct: 102 KRTGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSV--PERSDIGTSVIQVTATDADDGM 159
Query: 709 YGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG- 767
YGN V + + D T +DRE+R+ Y++ + A+ G G
Sbjct: 160 YGNSAKLVYSISQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRGGL 219
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
G V I + D NDNPP F + Y+ + E+S+ GT + I+A D D G NA +
Sbjct: 220 TGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPV---GRIRAADKDIGENAEMYF 276
Query: 828 TLF-GEGKEMFDV--DENT--GVVKFIGDSLDREKKIMYKLSLVARDT 870
T+ G+G + FD+ D+ T GV+ + LD EKK Y + + ++T
Sbjct: 277 TIVSGDGLDTFDIFTDKATQEGVIT-VSKPLDYEKKPSYTVEIQVQNT 323
Score = 80.6 bits (190), Expect = 3e-13
Identities = 116/451 (25%), Positives = 196/451 (43%), Gaps = 54/451 (11%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLT 506
+ L D NDN P F +Y S+ + +GT + +V A D D +GM + +++
Sbjct: 116 IKLHDINDNEPHF-SQEVYTGSVPERSDIGTSVIQVTATDAD---DGMYGNSAKLVYSIS 171
Query: 507 ITSP-FKINPNTGTVSVAESPILEGR-----HALFVEASDQPANPSERRYSLAVVTIEVT 560
P F ++PNTG + A P R + + +EA D +R + +T
Sbjct: 172 QGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDM---AGQRGGLTGTTVVNIT 228
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHG----- 613
+ P P F + Y+F V + GT VG+IR D E ++ + ++ G
Sbjct: 229 LTDVNDNP--PRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIVSGDGLDT 286
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN-----ATVHV-V 667
++ A +E GVITV L +P Y E + ++ ATV + V
Sbjct: 287 FDIFTDKATQE--GVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAV 344
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGN-VRFLIANQQD 725
+ DE + K ++ + VKE++A G A+G + S+I +G N V++ I + D
Sbjct: 345 EDVDEPPLFDKASY---LMEVKEDAAVGVALGSV-----SAIDPDGARNIVKYAIDRRTD 396
Query: 726 VTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNP 784
+ + +G++F K LDRE+ + ++VIA + + V I++ D NDN
Sbjct: 397 MDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHV-PVFIHLLDVNDNA 455
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE-GTNALFMYTLFGEG--KEMF---D 838
P YE F+ ++ ++A D DE F ++L EG + F D
Sbjct: 456 PTLA-TVYETFVSRPNQ-----NRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRSNFTIRD 509
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARD 869
+NT + S R ++ MY + +V D
Sbjct: 510 NGDNTASILTRRASYSRLQQSMYLVPVVITD 540
Score = 78.2 bits (184), Expect = 2e-12
Identities = 112/439 (25%), Positives = 185/439 (42%), Gaps = 37/439 (8%)
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEA 538
IGK+++ D D G NG+V Y L I F I+ N G + E + ++A
Sbjct: 43 IGKLQS-DQDHG-NGLVKYVLSGEGAGNI---FIIDENNGDLHATRRLDREEKAYYILKA 97
Query: 539 SDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVN 598
+ ++ TI++ N+P F Y V IGTSV Q+
Sbjct: 98 TVVNKRTGQKLEPETEFTIKL-HDINDNEPH---FSQEVYTGSVPERSDIGTSVIQVTAT 153
Query: 599 DAFE-QNDVSYDLLHGYEEGVP-FAVEERSGVITVV---DDLSRYNRPMYD--FEAVALQ 651
DA + S L++ +G P F+V+ +GVI D+ R R Y EA +
Sbjct: 154 DADDGMYGNSAKLVYSISQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMA 213
Query: 652 -ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIY 709
+ L+ T + + DVND + + F V E+S +G +G+I + I
Sbjct: 214 GQRGGLTGTTVVNITLTDVNDNPPRFTQSIYQ---FRVPESSESGTPVGRIRAAD-KDIG 269
Query: 710 GNGTGNVRFLIANQQDVTDDIA--IAEDGTIFTQKPLDREKRDVYRMTVIAEFN----KG 763
N + + D D ++G I KPLD EK+ Y + + + +
Sbjct: 270 ENAEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRF 329
Query: 764 VISGA-GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTN 822
+ G+ + V I +ED D PP+F+ A+Y + E++ +G + + A D D N
Sbjct: 330 MSPGSKDVATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVAL---GSVSAIDPDGARN 385
Query: 823 AL-FMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD--TGGLSSEAEL 879
+ + + +F+V G V F+ SLDRE+ + +S++A + SS +
Sbjct: 386 IVKYAIDRRTDMDHLFNVHPGNGSV-FLLKSLDREESAWHNISVIATELHNSRQSSHVPV 444
Query: 880 IIMIGDENDNKPEFNQIEE 898
I + D NDN P + E
Sbjct: 445 FIHLLDVNDNAPTLATVYE 463
Score = 72.5 bits (170), Expect = 8e-11
Identities = 56/235 (23%), Positives = 101/235 (42%), Gaps = 4/235 (1%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
V +TL D NDN P F S +Y+F + +++ GT +G+++A D D+G+N + + +
Sbjct: 225 VNITLTDVNDNPPRFTQS-IYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIVSGDG 283
Query: 505 LTITSPFKIN-PNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGT 563
L F G ++V++ E + + VE Q R S + R
Sbjct: 284 LDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIA 343
Query: 564 KGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVPFAV 622
+ + P F A Y V + +G ++G + D +N V Y + + F V
Sbjct: 344 VEDVDEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPDGARNIVKYAIDRRTDMDHLFNV 403
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVVDVNDERGVL 676
+G + ++ L R ++ +A + N+ S +H++DVND L
Sbjct: 404 HPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFIHLLDVNDNAPTL 458
Score = 70.5 bits (165), Expect = 3e-10
Identities = 51/168 (30%), Positives = 76/168 (45%), Gaps = 9/168 (5%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
DQD G G ++Y L +F +D NG L + LD + + V+ + Q
Sbjct: 49 DQDHGNGL-VKYVLSGEGAGNIFIIDENNGDLHATRRLDREEKAYYILKATVVNKRTGQK 107
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG-- 339
P + I+L D+NDN P F + Y S+ E G SV+QV ATD D G G
Sbjct: 108 LEP----ETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNS 163
Query: 340 -EFTYQLDDPKGAFSIDPRSGWL-TVRNQTVLDREAHSSLRMKVYAKE 385
+ Y + FS+DP +G + T +DRE ++ + AK+
Sbjct: 164 AKLVYSISQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKD 211
Score = 53.2 bits (122), Expect = 5e-05
Identities = 69/280 (24%), Positives = 115/280 (41%), Gaps = 30/280 (10%)
Query: 884 GDENDNKPEFNQIEENSKVRIHRETKLNGTA--GFTIIEVKPKN-KFALDVDQLGPLFLI 940
GD + + E Q+ +K + L GT T+ +V +F + Q F +
Sbjct: 193 GDMDREQREHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQSIYQ----FRV 248
Query: 941 PENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE-RHG 999
PE+ GT + ++ A D D G N ++ + +S D L+ F + G
Sbjct: 249 PESSESGTPVGRIRAADKDIGENAEMYFTI----------VSGDGLDTFDIFTDKATQEG 298
Query: 1000 HVIVARSLPPES------EFRLNISALDGGNLN----DNISVRVFVKDVNDHFPVFKKTW 1049
+ V++ L E E ++ + +D ++ D +VR+ V+DV D P+F K
Sbjct: 299 VITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAVEDV-DEPPLFDKAS 357
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELD 1109
Y V+E LG V A D D +N + +D D F + P G + + LD
Sbjct: 358 YLMEVKEDAAVGVALGSVSAIDPDGARNIVKYAIDRRTDMDHLFNVHPGNGSVFLLKSLD 417
Query: 1110 RETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSP 1149
RE + ++V+A + DVNDN+P
Sbjct: 418 REESAWHNISVIATEL-HNSRQSSHVPVFIHLLDVNDNAP 456
Score = 51.2 bits (117), Expect = 2e-04
Identities = 76/291 (26%), Positives = 115/291 (39%), Gaps = 35/291 (12%)
Query: 83 VTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAP--IGPSLTIPLTVPRG--- 137
V + + DVNDN P F + Y V E + +G A IG + + T+ G
Sbjct: 225 VNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIVSGDGL 284
Query: 138 --LTIFKDIRAFDR--------DKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
IF D + D P+ V + + D F S + V
Sbjct: 285 DTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAV 344
Query: 188 LDYDAG---DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRK-L 243
D D DK L+ + + + + AID D G ++Y + D L
Sbjct: 345 EDVDEPPLFDKASYLMEVKEDAAVGVAL---GSVSAIDPD-GARNIVKYAIDRRTDMDHL 400
Query: 244 FSLDSVNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F++ NGS+FL K LD + A HN+ V A++L+N +++ V I LLD+ND
Sbjct: 401 FNVHPGNGSVFLLKSLDREESAWHNIS-------VIATELHNSRQSSHVPVFIHLLDVND 453
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAF 352
N P Y + + PN + V A D D+ G Y P+G +
Sbjct: 454 NAPTL-ATVYETFV--SRPNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTY 501
Score = 46.4 bits (105), Expect = 0.006
Identities = 24/69 (34%), Positives = 33/69 (47%)
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
T V I L D+NDN P F Y + E+ +G V ++ A DKD GEN E + +
Sbjct: 220 TGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIV 279
Query: 347 DPKGAFSID 355
G + D
Sbjct: 280 SGDGLDTFD 288
Score = 43.6 bits (98), Expect = 0.043
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL----DSVNGSLFLEKELDLDAEHNLQANTFV 273
I A D+D+G A + + ++SG+ F + + G + + K LD + + + T
Sbjct: 261 IRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKK---PSYTVE 317
Query: 274 LQVQASQLN----NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+QVQ +Q++ +P A V I + D+ D P F+ Y + + E+ G ++ V
Sbjct: 318 IQVQNTQIDPRFMSPGSKDVATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVS 376
Query: 330 ATDKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
A D D G Y +D D F++ P +G + + LDRE + + V A E
Sbjct: 377 AIDPD-GARNIVKYAIDRRTDMDHLFNVHPGNGSVFLLKS--LDREESAWHNISVIATEL 433
Query: 387 NPS 389
+ S
Sbjct: 434 HNS 436
>UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadherin19
- Rattus norvegicus (Rat)
Length = 770
Score = 87.0 bits (206), Expect = 3e-15
Identities = 95/345 (27%), Positives = 161/345 (46%), Gaps = 32/345 (9%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-LLHGYEEGVP-FAVEERSGV 628
P F+ PYE V GT V ++ NDA + + +L+ E+G P F+VE +GV
Sbjct: 144 PRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQPYFSVEPTTGV 203
Query: 629 ITVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
I + + R + Y A L + LS T ++ + D+ND + + + +
Sbjct: 204 IRISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYR--- 260
Query: 686 FHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---AEDGTIFTQ 741
F + E++ +G IG+I + I N + + I + + DI I ++G + +
Sbjct: 261 FTISESAPSGTTIGKIMAYD-DDIGENA--EMDYSIEDDESQIFDIVIDNETQEGIVILK 317
Query: 742 KPLDREKRDVYRMTVIAEFNKGV---ISGAGIYQVTIYIE---DENDNPPVFEHATYEGF 795
K +D E ++ Y + V + N V ++ A + T YI+ ++ D PP F Y
Sbjct: 318 KKVDFEHQNHYGIRVKVK-NCHVDEELAPAHVNASTTYIKVQVEDEDEPPTFLLPYYIFE 376
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
I E GT M + A D D + + Y+L G +MFD++ N +V + LDR
Sbjct: 377 IPEGKPYGT---MVGTVSAVDPDRRQSPM-RYSLIGS--KMFDINGNGTIVTT--NLLDR 428
Query: 856 EKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEE 898
E Y LS+ A +T + S A + + + + ND+ PEF+Q+ E
Sbjct: 429 EVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHAPEFSQLYE 473
Score = 77.8 bits (183), Expect = 2e-12
Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 13/192 (6%)
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY--RMTVI-AEFNKGVISG 767
NG + ++ + D + I + G IF + LDREK+ +Y R VI K V
Sbjct: 71 NGNNSFQYKLLGTGDGSFSID-EKTGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEPE 129
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+ + I + D NDN P F YE + E S GT + A D G +A +Y
Sbjct: 130 S---EFVIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILY 186
Query: 828 TLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMI 883
L +G+ F V+ TGV++ I +DRE + Y + + A+D G LS + I +
Sbjct: 187 NL-EQGQPYFSVEPTTGVIR-ISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKL 244
Query: 884 GDENDNKPEFNQ 895
D NDNKP F +
Sbjct: 245 SDINDNKPIFKE 256
Score = 72.5 bits (170), Expect = 8e-11
Identities = 108/467 (23%), Positives = 197/467 (42%), Gaps = 48/467 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P F+ YE + + GT + KV A D P G + +LY+L++
Sbjct: 134 IRVSDVNDNEPRFLDEP-YEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQ 192
Query: 504 NLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
F + P TG + ++ L+ + + ++A D P ++I+++
Sbjct: 193 PY-----FSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPGALS-GTTTISIKLS- 245
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP 619
NKP F + Y F + + GT++G+I +D E ++ Y + +
Sbjct: 246 DINDNKPI---FKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDESQIFD 302
Query: 620 FAV--EERSGVITVVDDLSRYNRPMYDFEAVAL-----QENANLSIVTNATVHVVDVNDE 672
+ E + G++ + + ++ Y +E A + + T V V DE
Sbjct: 303 IVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVEDE 362
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + +++ E G G + T + +R+ + + + D I
Sbjct: 363 D----EPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRRQSPMRYSLIGSK-MFD---I 414
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGAGIYQVTIYIEDENDNPPVFEHA 790
+GTI T LDRE Y ++V A +N IS A +Y + I ND+ P F
Sbjct: 415 NGNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNI---NDHAPEFSQL 471
Query: 791 TYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF---DVDENTGVV- 846
YE ++ EN++ G I+ + I ++ E + F +++ F D +NT V+
Sbjct: 472 -YETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQDNTAVIL 530
Query: 847 -KFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNK 890
G SL +E+ + Y + L+A D G L+S L I + D D++
Sbjct: 531 SNRAGFSL-KEETVFYMIILIA-DNGIPPLTSTNTLTIQVCDCGDSR 575
Score = 70.9 bits (166), Expect = 2e-10
Identities = 48/169 (28%), Positives = 85/169 (50%), Gaps = 14/169 (8%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A + Y L G + FS++ G + + ++D + + +T+ + +QA
Sbjct: 173 ADDPTSGYHARILYNLEQG--QPYFSVEPTTGVIRISSKMDRELQ-----DTYCVIIQAK 225
Query: 280 Q-LNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
L P + + I+L D+NDN P F+ FY +I E+ P+G ++ ++MA D D GE
Sbjct: 226 DMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGE 285
Query: 338 NGEFTYQL-DDPKGAFSI----DPRSGWLTVRNQTVLDREAHSSLRMKV 381
N E Y + DD F I + + G + ++ + + + H +R+KV
Sbjct: 286 NAEMDYSIEDDESQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKV 334
Score = 68.9 bits (161), Expect = 1e-09
Identities = 57/224 (25%), Positives = 109/224 (48%), Gaps = 33/224 (14%)
Query: 921 VKPKNKFAL---DVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNG-QIRYE 969
V+P+++F + DV+ P FL +PE P GT +IK+ A D D +G R
Sbjct: 126 VEPESEFVIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARIL 185
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESE--FRLNISALD----GG 1023
+N E P YF + G + ++ + E + + + I A D G
Sbjct: 186 YNLEQGQP-------------YFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPG 232
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
L+ ++ + + D+ND+ P+FK+++Y F + E+ + +GK+ A D D G+NA + Y
Sbjct: 233 ALSGTTTISIKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYS 292
Query: 1084 IQPSDT---DLPFEISPLTGVLSVNGELDRETEDKYILTVVARD 1124
I+ ++ D+ + G++ + ++D E ++ Y + V ++
Sbjct: 293 IEDDESQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKN 336
Score = 62.9 bits (146), Expect = 7e-08
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 12/251 (4%)
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
VG++R + N Y LL G +G F+++E++G I + L R + +Y A +
Sbjct: 62 VGRLRSDLDNGNNSFQYKLL-GTGDG-SFSIDEKTGDIFAMQKLDREKQSLYILRAQVID 119
Query: 652 ENANLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
++ + + V DVND L + I+ + G + ++ N +
Sbjct: 120 TTIGKAVEPESEFVIRVSDVNDNEPRFLDEPYEAIVPEMSPE--GTFVIKVT-ANDADDP 176
Query: 710 GNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-A 768
+G + R L +Q G I +DRE +D Y + + A+ G +
Sbjct: 177 TSGY-HARILYNLEQGQPYFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPGALS 235
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
G ++I + D NDN P+F+ + Y I E++ GT I I A D D G NA Y+
Sbjct: 236 GTTTISIKLSDINDNKPIFKESFYRFTISESAPSGTTI---GKIMAYDDDIGENAEMDYS 292
Query: 829 LFGEGKEMFDV 839
+ + ++FD+
Sbjct: 293 IEDDESQIFDI 303
Score = 62.1 bits (144), Expect = 1e-07
Identities = 47/169 (27%), Positives = 73/169 (43%), Gaps = 11/169 (6%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALD---GGNLNDNISVRVFVKDVNDHFPVFK 1046
F I+E+ G + + L E + + L +D G + + V DVND+ P F
Sbjct: 88 FSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEPESEFVIRVSDVNDNEPRFL 147
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
Y V E + KV A DAD G +A + Y ++ F + P TGV+
Sbjct: 148 DEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQPY--FSVEPTTGVIR 205
Query: 1104 VNGELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKF 1151
++ ++DRE +D Y + + A+D G D+NDN P F
Sbjct: 206 ISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIF 254
Score = 60.5 bits (140), Expect = 3e-07
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 17/216 (7%)
Query: 180 PVLLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQ------DLGVGA-TLR 232
P L + + L + + + A + K+ + PE + I DL G + +
Sbjct: 18 PCLKVAETLKIEKAQRAVPSLGRAKRGWVWKQFVVPEEMDTIQHVGRLRSDLDNGNNSFQ 77
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y+L+ D FS+D G +F ++LD + + V+ + P ++
Sbjct: 78 YKLLGTGDGS-FSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEP----ESEF 132
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD---QGENGEFTYQLDDPK 349
I + D+NDN P F + Y + E P G V++V A D D G + Y L+ +
Sbjct: 133 VIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQ 192
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
FS++P +G +R + +DRE + + + AK+
Sbjct: 193 PYFSVEPTTG--VIRISSKMDRELQDTYCVIIQAKD 226
Score = 57.6 bits (133), Expect = 2e-06
Identities = 56/242 (23%), Positives = 101/242 (41%), Gaps = 21/242 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + L D NDN P+F S Y F++ +A GT IGK+ A D D+G+N + Y
Sbjct: 234 LSGTTTISIKLSDINDNKPIFKES-FYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYS 292
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEAS------DQPANPSERRYSL 552
++ + G V + + E ++ + D+ P+ S
Sbjct: 293 IEDDESQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNAST 352
Query: 553 AVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQI-RVNDAFEQNDVSYDLL 611
+ ++V ++ + P F+ Y F + GT VG + V+ Q+ + Y L+
Sbjct: 353 TYIKVQVE-----DEDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRRQSPMRYSLI 407
Query: 612 HGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVH--VVDV 669
G +G I + L R Y+ +V E N+ +++A V+ V+++
Sbjct: 408 -----GSKMFDINGNGTIVTTNLLDREVSAWYNL-SVTATETYNVQQISSAHVYVQVLNI 461
Query: 670 ND 671
ND
Sbjct: 462 ND 463
Score = 46.4 bits (105), Expect = 0.006
Identities = 57/236 (24%), Positives = 102/236 (43%), Gaps = 16/236 (6%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFN---SEVY-IPPSKLSADALEVKRYFV 993
F I E+ P GTTI K+ A D D G N ++ Y S+++ I + + + + + V
Sbjct: 261 FTISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDESQIFDIVIDNETQEGIVILKKKV 320
Query: 994 INERHGHVIVARSLPPESEFRLNISALDGGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNF 1052
E H + + ++ L ++N + + ++V V+D D P F +Y F
Sbjct: 321 DFEHQNHYGIRVKV---KNCHVD-EELAPAHVNASTTYIKVQVED-EDEPPTFLLPYYIF 375
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRET 1112
+ E + ++G V A D D Q+ + Y + S F+I+ G + LDRE
Sbjct: 376 EIPEGKPYGTMVGTVSAVDPDRRQSP-MRYSLIGSKM---FDING-NGTIVTTNLLDREV 430
Query: 1113 EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
Y L+V A + ++ND++P+F E ++ E+ E+
Sbjct: 431 SAWYNLSVTATET-YNVQQISSAHVYVQVLNINDHAPEFSQLYETYVCENAESGEI 485
Score = 45.2 bits (102), Expect = 0.014
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 11/118 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+ A+D D + +RY LI K+F ++ NG++ LD + + + L V
Sbjct: 390 VSAVDPDRRQ-SPMRYSLIGS---KMFDING-NGTIVTTNLLDREV-----SAWYNLSVT 439
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
A++ N + + A V +++L++ND+ PEF Y + EN +G + + A D+D+
Sbjct: 440 ATETYNVQQISSAHVYVQVLNINDHAPEFS-QLYETYVCENAESGEIIQTISAIDRDE 496
Score = 44.8 bits (101), Expect = 0.018
Identities = 44/175 (25%), Positives = 79/175 (45%), Gaps = 13/175 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL----DSVNGSLFLEKELDLDAEHNLQANTFV 273
I A D D+G A + Y I ++ ++F + ++ G + L+K++D + +++ V
Sbjct: 276 IMAYDDDIGENAEMDYS-IEDDESQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKV 334
Query: 274 LQVQASQLNNP--LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ P + + +++++ D D P F + +Y I E P G V V A
Sbjct: 335 KNCHVDEELAPAHVNASTTYIKVQVED-EDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAV 393
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
D D+ ++ Y L K F I +G T+ +LDRE + + V A ET
Sbjct: 394 DPDRRQS-PMRYSLIGSK-MFDI---NGNGTIVTTNLLDREVSAWYNLSVTATET 443
Score = 43.2 bits (97), Expect = 0.056
Identities = 51/173 (29%), Positives = 67/173 (38%), Gaps = 30/173 (17%)
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
W F V E T + +G++ +D D G N+ + D F I TG + +L
Sbjct: 47 WKQFVVPEEMDTIQHVGRL-RSDLDNGNNSFQYKLLGTGDGS--FSIDEKTGDIFAMQKL 103
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL 1168
DRE + YIL D DVNDN P+F DE E
Sbjct: 104 DREKQSLYILRAQVIDTTIGKAVEPESEFVIRVSDVNDNEPRF--LDEPYE--------- 152
Query: 1169 SNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG-NGLILYSLPQ 1220
A + E +P GT V KV AND D +G + ILY+L Q
Sbjct: 153 ---------------AIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQ 190
Score = 39.1 bits (87), Expect = 0.92
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
Query: 433 EYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD 488
E Y+ Q +S +V V +L+ ND+ P F S LYE + NA+ G +I + A+D D
Sbjct: 442 ETYNVQQISSAHVYVQVLNINDHAPEF--SQLYETYVCENAESGEIIQTISAIDRD 495
Score = 38.7 bits (86), Expect = 1.2
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 22/133 (16%)
Query: 1287 NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPH 1346
N +Y +L D +F ID + G ++ ++ DRE + Y I+RA+
Sbjct: 73 NNSFQYKLLGTGDG----SFSIDEKTGDIFAMQKLDREKQSLY--ILRAQ---------- 116
Query: 1347 MIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKG 1406
V + + + + + V+R+ DVNDN P+F + P +P +P G V+++
Sbjct: 117 ----VIDTTIGKAVEPESEFVIRVSDVNDNEPRFL--DEPYEAIVPEMSPEGTFVIKVTA 170
Query: 1407 AIGHHPTASRTVR 1419
PT+ R
Sbjct: 171 NDADDPTSGYHAR 183
Score = 38.3 bits (85), Expect = 1.6
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ + DVNDN P FLD PY V E++P G
Sbjct: 134 IRVSDVNDNEPRFLDEPYEAIVPEMSPEG 162
Score = 36.7 bits (81), Expect = 4.9
Identities = 13/37 (35%), Positives = 24/37 (64%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+S ++++ + D+NDN PIF ++ Y T+ E P+G
Sbjct: 234 LSGTTTISIKLSDINDNKPIFKESFYRFTISESAPSG 270
>UniRef50_UPI0000F1F8F4 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 626
Score = 85.4 bits (202), Expect = 1e-14
Identities = 65/256 (25%), Positives = 130/256 (50%), Gaps = 22/256 (8%)
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+ N + +VD+ND + H+ + S A G+ F + + G+ +++
Sbjct: 104 IFNIEIEIVDINDNAPQFRRDT-----IHL-DISESTAAGERFSLSNAVDPDIGSNSIKT 157
Query: 719 LIANQQDVTD-DIAIAEDGTIFT----QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
++ D D ++ DG+ F +KPLDRE++ + + ++ + GV + +G +
Sbjct: 158 YYLSESDHFDIEMQTGRDGSKFADLILKKPLDREEQASHNL-ILTAVDGGVPARSGTASI 216
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA--LFMYTLFG 831
+ + D NDN P F+ +Y + EN+ IG+ + + A+D DEG+N+ L+ Y+L+
Sbjct: 217 IVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVK---LNASDKDEGSNSDLLYSYSLYT 273
Query: 832 EGK--EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDEN 887
K + F ++ N G ++ + + ++ E +Y + ++A D G L+ + ++ I+I D N
Sbjct: 274 SEKTQQTFSLNPNNGEIR-VKELINYEDFRIYDMEIIATDKGANSLTGKCKVKILITDMN 332
Query: 888 DNKPEFNQIEENSKVR 903
DN PE + S V+
Sbjct: 333 DNHPEISIRSVTSPVK 348
Score = 72.5 bits (170), Expect = 8e-11
Identities = 45/153 (29%), Positives = 78/153 (50%), Gaps = 10/153 (6%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELD--LDAEHNLQANTFVLQV 276
+A+D D+G + Y L + + +GS F + L LD E N + V
Sbjct: 144 NAVDPDIGSNSIKTYYLSESDHFDIEMQTGRDGSKFADLILKKPLDREEQASHNLILTAV 203
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
P ++ A + + +LD NDN P+F+ D Y I++ EN P G V+++ A+DKD+G
Sbjct: 204 DGGV---PARSGTASIIVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVKLNASDKDEG 260
Query: 337 ENGE--FTYQL---DDPKGAFSIDPRSGWLTVR 364
N + ++Y L + + FS++P +G + V+
Sbjct: 261 SNSDLLYSYSLYTSEKTQQTFSLNPNNGEIRVK 293
Score = 72.1 bits (169), Expect = 1e-10
Identities = 63/224 (28%), Positives = 101/224 (45%), Gaps = 23/224 (10%)
Query: 911 NGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
+GTA I+ V N A D+ + EN PIG+ ++KLNA D D G N + Y +
Sbjct: 211 SGTASI-IVRVLDTNDNAPQFDKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSY 269
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR---LNISALDGG--NL 1025
+ +Y + + ++ F +N +G + V + L +FR + I A D G +L
Sbjct: 270 S--LY--------TSEKTQQTFSLNPNNGEIRV-KELINYEDFRIYDMEIIATDKGANSL 318
Query: 1026 NDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ 1085
V++ + D+ND+ P V+E V+ V +D D G+N + I
Sbjct: 319 TGKCKVKILITDMNDNHPEISIRSVTSPVKEDVAVNTVIAVVSVSDKDSGENGQVDIHI- 377
Query: 1086 PSDTDLPFEISPLTG---VLSVNGELDRETEDKYILTVVARDNG 1126
DLPF + + L V+ LDRE +Y +T+ D G
Sbjct: 378 --SADLPFALKKSSDNYYELLVSEPLDREKLPEYDITITVTDRG 419
Score = 64.9 bits (151), Expect = 2e-08
Identities = 63/272 (23%), Positives = 120/272 (44%), Gaps = 18/272 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ V +LD NDN P F + Y ++ NA +G+++ K+ A D D G N +LY +
Sbjct: 215 SIIVRVLDTNDNAPQF-DKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSYSLYT 273
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGRHALFVE--ASDQPANPSERRYSLAVVTIEVTR 561
+ F +NPN G + V E E +E A+D+ AN + + ++ ++
Sbjct: 274 SEKTQQTFSLNPNNGEIRVKELINYEDFRIYDMEIIATDKGANSLTGKCKVKILITDM-- 331
Query: 562 GTKGNKPDIP-DFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPF 620
N P+I + +P V +V + T + + V+D + D +H +PF
Sbjct: 332 --NDNHPEISIRSVTSP----VKEDVAVNTVIAVVSVSDKDSGENGQVD-IH-ISADLPF 383
Query: 621 AVEERSG---VITVVDDLSRYNRPMYDFE-AVALQENANLSIVTNATVHVVDVNDERGVL 676
A+++ S + V + L R P YD V + N LS T+ ++D+ R
Sbjct: 384 ALKKSSDNYYELLVSEPLDREKLPEYDITITVTDRGNPPLSDNETITLELLDIRTMRMFS 443
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSI 708
+ + + + +++ A+ +S++
Sbjct: 444 YRDSRDQRLVVIAKDNGEPALSATVTIKLSTV 475
Score = 63.3 bits (147), Expect = 5e-08
Identities = 76/331 (22%), Positives = 137/331 (41%), Gaps = 27/331 (8%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVL 496
E + N+E+ ++D NDN P F ++ + + G AVDPD+G N +
Sbjct: 99 ENPVRIFNIEIEIVDINDNAPQFRRDTIH-LDISESTAAGERFSLSNAVDPDIGSNSIKT 157
Query: 497 YDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLA 553
Y L + + I + + + + P+ + H L + A D P+ R A
Sbjct: 158 YYLSESDHFDIEMQTGRDGSKFADLILKKPLDREEQASHNLILTAVDGGV-PA--RSGTA 214
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYD 609
+ + V T N P F Y + N IG+ V ++ +D E ++ SY
Sbjct: 215 SIIVRVL-DTNDN---APQFDKDSYTINLTENAPIGSLVVKLNASDKDEGSNSDLLYSYS 270
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN-LSIVTNATVHVVD 668
L + F++ +G I V + ++ + +YD E +A + AN L+ + + D
Sbjct: 271 LYTSEKTQQTFSLNPNNGEIRVKELINYEDFRIYDMEIIATDKGANSLTGKCKVKILITD 330
Query: 669 VNDER-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVT 727
+ND + ++ SP+ V N+ A + ++S G V I+ D+
Sbjct: 331 MNDNHPEISIRSVTSPVKEDVAVNTVIAVV------SVSDKDSGENGQVDIHIS--ADLP 382
Query: 728 DDIAIAEDG--TIFTQKPLDREKRDVYRMTV 756
+ + D + +PLDREK Y +T+
Sbjct: 383 FALKKSSDNYYELLVSEPLDREKLPEYDITI 413
Score = 55.2 bits (127), Expect = 1e-05
Identities = 56/208 (26%), Positives = 85/208 (40%), Gaps = 38/208 (18%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
++ + + D+ND+ P F++ + ++ E+ +A D D G N+ TY++ SD
Sbjct: 106 NIEIEIVDINDNAPQFRRDTIHLDISESTAAGERFSLSNAVDPDIGSNSIKTYYLSESDH 165
Query: 1090 DLPFEISPLTGV-------LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
F+I TG L + LDRE + + L + A D G
Sbjct: 166 ---FDIEMQTGRDGSKFADLILKKPLDREEQASHNLILTAVDGGVPARSGTASIIVRVL- 221
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
D NDN+P+ FD+ Y + ENAPIG+ V K+ A+
Sbjct: 222 DTNDNAPQ---FDK-----------------------DSYTINLTENAPIGSLVVKLNAS 255
Query: 1203 DTDFIGNGNGLILYSL-PQRKNQQNLGL 1229
D D N + L YSL K QQ L
Sbjct: 256 DKDEGSNSDLLYSYSLYTSEKTQQTFSL 283
Score = 52.0 bits (119), Expect = 1e-04
Identities = 61/280 (21%), Positives = 119/280 (42%), Gaps = 34/280 (12%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIF-LIAP-IGPS------------ 127
++ + I D+NDN P F H+ + E T GE+ + + P IG +
Sbjct: 106 NIEIEIVDINDNAPQFRRDTIHLDISESTAAGERFSLSNAVDPDIGSNSIKTYYLSESDH 165
Query: 128 LTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKV 187
I + R + F D+ KP ++++ DG S +++ +V
Sbjct: 166 FDIEMQTGRDGSKFADLIL---KKPLDREEQASHNLILTAVDGGVPARSGTASIIV--RV 220
Query: 188 LDYDAG----DKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYEL---ISGND 240
LD + DK+ + + I ++ ++A D+D G + L Y S
Sbjct: 221 LDTNDNAPQFDKDSYTINLTENAPIGSLVV---KLNASDKDEGSNSDLLYSYSLYTSEKT 277
Query: 241 RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
++ FSL+ NG + +++ ++ + + +++ A+ T + +V+I + D+N
Sbjct: 278 QQTFSLNPNNGEIRVKELINYE-----DFRIYDMEIIATDKGANSLTGKCKVKILITDMN 332
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE 340
DN PE + + E++ + V +DKD GENG+
Sbjct: 333 DNHPEISIRSVTSPVKEDVAVNTVIAVVSVSDKDSGENGQ 372
Score = 50.0 bits (114), Expect = 5e-04
Identities = 36/130 (27%), Positives = 68/130 (52%), Gaps = 7/130 (5%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEH-NLQANTFVLQVQASQLNNPLKTAQ 289
+R ++IS ++K ++ G L++ +++D + + A T ++++ L NP++
Sbjct: 50 MRLDIIS--NKKYLDVNKETGELYVLEKMDREYLCLSKTATTCFIKMEVI-LENPVRIFN 106
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPK 349
+EIE++D+NDN P+F D ++ I E+ G A D D G N TY L +
Sbjct: 107 --IEIEIVDINDNAPQFRRDTIHLDISESTAAGERFSLSNAVDPDIGSNSIKTYYLSE-S 163
Query: 350 GAFSIDPRSG 359
F I+ ++G
Sbjct: 164 DHFDIEMQTG 173
Score = 43.6 bits (98), Expect = 0.043
Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
+G I ++ ++ E +Y M +IA +KG S G +V I I D NDN P +
Sbjct: 287 NGEIRVKELINYEDFRIYDMEIIAT-DKGANSLTGKCKVKILITDMNDNHPEISIRSVTS 345
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLD 854
+ E+ + T I ++ +D D G N + + + + + LD
Sbjct: 346 PVKEDVAVNTVIA---VVSVSDKDSGENGQVDIHISADLPFALKKSSDNYYELLVSEPLD 402
Query: 855 REKKIMYKLSLVARDTG 871
REK Y +++ D G
Sbjct: 403 REKLPEYDITITVTDRG 419
>UniRef50_Q6P3M3 Cluster: Cadherin 17, LI cadherin; n=4; Danio
rerio|Rep: Cadherin 17, LI cadherin - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 868
Score = 85.4 bits (202), Expect = 1e-14
Identities = 158/698 (22%), Positives = 279/698 (39%), Gaps = 74/698 (10%)
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
+SG + S +G L+LE+ L+ E L L+ P A+V ++
Sbjct: 60 VSGETEDKIRISS-DGWLYLEQPLEWSPEKKHHLLIEALSEDGKTLDGP-----AQVVLQ 113
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG--ENGEFTYQLDDPKGA-- 351
++D+N+N P F Y+ SI E+ P G +QV A+D D EN + + + +
Sbjct: 114 VIDVNNNPPVFSESQYSGSIREHSPAGVPFVQVFASDADDPNTENTQLRFSIVNQIPIVG 173
Query: 352 ----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQP 407
F I+P +G + + +A S+ +P V+ + I K
Sbjct: 174 QTFFFGINPNNGQIFTTEEGAEFLKARPSVTYSRGEVRGSPDVLKKKFEDYCIPK-NNIA 232
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVE------VTLLDANDNNPVFVP 461
LE N P K ++ +T N+ D V E V L + + +
Sbjct: 233 LENN-PFYKCV----ERAERRTVNV-LQDPDYALIVRAEDLGGNAVNSLSSTTRVNIAIL 286
Query: 462 SNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVS 521
NL+ + T + N LY L++ L+ PF IN + G +
Sbjct: 287 QNLWVSPGPITIRENTDEEYPMYLATMRANNPTALYRLEQKEILSF--PFTINQD-GDIY 343
Query: 522 VAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYE 579
V E + + L V A D+ E+ + V+ + + + P I D A +E
Sbjct: 344 VTGPLDREEKEMYILVVIAEDEQGVELEKPMEIPVLVQD-----ENDNPPICD--EALFE 396
Query: 580 FWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVP-------FAVEERSGVITVV 632
V +G S+G + +D ++ +S L + P F+++ +G I V
Sbjct: 397 --VQEKEPVGNSIGHLPAHDNDKEGTLSSALTYTLRSQTPTKPSDKMFSIDPNTGEIKVA 454
Query: 633 D-DLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN 691
+ + R P Y+ + A + V+D+NDE + K + + V E
Sbjct: 455 NQNFQRKQVPQYELTFEVTDQV--FFTKCKAIIKVIDINDEIPIFEKNDYGT--YSVPEL 510
Query: 692 S-AGAAIGQIFHTNMSSIYGNGTGNVRFLI-ANQQDVTDDIAIAED---GTIFTQKPLDR 746
+ G + I T+ G G+ V + I A I + E+ G ++ +PLD
Sbjct: 511 AEVGTTLLNIKATDADDT-GTGSSRVEYHITAGDPQNLFAIEVDEETGEGRVYIAQPLDY 569
Query: 747 EKRDVYRMTVIAEFNKGVISG-----AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSK 801
E + VY + + A + +I+G + V I + D D PP FE + EN
Sbjct: 570 ELQSVYNLKIDARNPEPLIAGVEYNDSSTTSVVIELVDV-DEPPKFEVEGLNVNVPENIT 628
Query: 802 IGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY 861
+GT ++ +A + + + G+ + +++ +TG +K +LDRE +
Sbjct: 629 VGT------LLMKAEAKDPEGKTIKFKMEGDEHKWLELNVDTGELK-TKAALDRETVDHF 681
Query: 862 KLSLVARDTGGLSSEAEL--IIMIGDENDNKPEFNQIE 897
L++ A +T G EAE+ I + D NDN P+ + +
Sbjct: 682 TLTITAYETEGSKMEAEMKVDIHLQDVNDNYPKLQKTQ 719
Score = 60.1 bits (139), Expect = 5e-07
Identities = 63/222 (28%), Positives = 92/222 (41%), Gaps = 21/222 (9%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
+ +PE +GTT++ + A D D G R E++ P + A+EV
Sbjct: 505 YSVPELAEVGTTLLNIKATDADDTGTGSSRVEYHITAGDPQNLF---AIEVDE----ETG 557
Query: 998 HGHVIVARSLPPE--SEFRLNISA------LDGGNLNDNISVRVFVKDVN-DHFPVFKKT 1048
G V +A+ L E S + L I A + G ND+ + V ++ V+ D P F+
Sbjct: 558 EGRVYIAQPLDYELQSVYNLKIDARNPEPLIAGVEYNDSSTTSVVIELVDVDEPPKFEVE 617
Query: 1049 WYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGEL 1108
N NV E +L K +A D + G+ F D E++ TG L L
Sbjct: 618 GLNVNVPENITVGTLLMKAEAKDPE-GKTIK---FKMEGDEHKWLELNVDTGELKTKAAL 673
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
DRET D + LT+ A + DVNDN PK
Sbjct: 674 DRETVDHFTLTITAYET-EGSKMEAEMKVDIHLQDVNDNYPK 714
Score = 48.8 bits (111), Expect = 0.001
Identities = 48/182 (26%), Positives = 95/182 (52%), Gaps = 18/182 (9%)
Query: 218 IHAID-QDLGVGAT-LRYELISGNDRKLFSLD----SVNGSLFLEKELD--LDAEHNLQA 269
I A D D G G++ + Y + +G+ + LF+++ + G +++ + LD L + +NL+
Sbjct: 520 IKATDADDTGTGSSRVEYHITAGDPQNLFAIEVDEETGEGRVYIAQPLDYELQSVYNLKI 579
Query: 270 NTFVLQ--VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQ 327
+ + + + N+ T+ V IEL+D+ D P+FEV+ N+++ EN+ G +++
Sbjct: 580 DARNPEPLIAGVEYNDSSTTS---VVIELVDV-DEPPKFEVEGLNVNVPENITVGTLLMK 635
Query: 328 VMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
A D +G+ +F + D+ K ++ +G L + + LDRE + + A ET
Sbjct: 636 AEAKD-PEGKTIKFKMEGDEHKW-LELNVDTGEL--KTKAALDRETVDHFTLTITAYETE 691
Query: 388 PS 389
S
Sbjct: 692 GS 693
Score = 44.8 bits (101), Expect = 0.018
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 12/133 (9%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKT 287
G T+++++ G++ K L+ G L + LD + + F L + A +
Sbjct: 643 GKTIKFKM-EGDEHKWLELNVDTGELKTKAALDRET-----VDHFTLTITAYETEGSKME 696
Query: 288 AQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE-FTYQLD 346
A+ +V+I L D+NDN P+ + I + + P L + A DKD GE FT+ +
Sbjct: 697 AEMKVDIHLQDVNDNYPKLQKTQGFICLQDMTP-----LTLTAMDKDADPYGEPFTFAIS 751
Query: 347 DPKGAFSIDPRSG 359
F I P G
Sbjct: 752 RKSQNFEIKPVDG 764
Score = 39.1 bits (87), Expect = 0.92
Identities = 53/200 (26%), Positives = 82/200 (41%), Gaps = 22/200 (11%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSG--LNGQIRYEFNSEVYIPPSKLSADALEVKRYFVI 994
LF + E P+G +I L A D D L+ + Y S+ PS + F I
Sbjct: 394 LFEVQEKEPVGNSIGHLPAHDNDKEGTLSSALTYTLRSQTPTKPSD---------KMFSI 444
Query: 995 NERHGHVIVARS---LPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWY- 1050
+ G + VA ++ L D ++ + V D+ND P+F+K Y
Sbjct: 445 DPNTGEIKVANQNFQRKQVPQYELTFEVTDQVFFTKCKAI-IKVIDINDEIPIFEKNDYG 503
Query: 1051 NFNVEEAQYTRRVLGKVDATDA-DFGQ-NANLTYFIQPSDTDLPF--EISPLTGV--LSV 1104
++V E L + ATDA D G ++ + Y I D F E+ TG + +
Sbjct: 504 TYSVPELAEVGTTLLNIKATDADDTGTGSSRVEYHITAGDPQNLFAIEVDEETGEGRVYI 563
Query: 1105 NGELDRETEDKYILTVVARD 1124
LD E + Y L + AR+
Sbjct: 564 AQPLDYELQSVYNLKIDARN 583
>UniRef50_UPI00015B58A5 Cluster: PREDICTED: similar to GA18227-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA18227-PA - Nasonia vitripennis
Length = 2301
Score = 85.0 bits (201), Expect = 1e-14
Identities = 52/163 (31%), Positives = 85/163 (52%), Gaps = 7/163 (4%)
Query: 737 TIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
T+ +D EK R ++A+ + + VTI++ D NDNPP F+ YE +
Sbjct: 423 TVRDNSMIDYEKFKSLRFKIVAQEVGPATNLSTSVPVTIFLRDVNDNPPTFDVPVYEVTL 482
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYT-LFGEGKEMFDVDENTGVVKF-IGDSLD 854
EN+ GT + + ATD D G YT + G+G F+++ ++G++ +G LD
Sbjct: 483 SENASAGTRVVQ---VHATDIDAGAFGRIQYTKIIGDGSAAFEMNPDSGMIAVSMGSILD 539
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
RE+ +L++ ARD G+ A L++ I D NDN P F++
Sbjct: 540 REQTAKLELTVEARDEDGRGMRGIAALMVNILDVNDNAPVFDK 582
Score = 76.6 bits (180), Expect = 5e-12
Identities = 121/462 (26%), Positives = 188/462 (40%), Gaps = 43/462 (9%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV 495
D + ++ VNV V + D D P+F + + + K G VI +V A D D G V
Sbjct: 216 DTRNIAGVNVVVVVQDVQDVPPIFTLAPPLT-KINNTVKPGDVILRVHAEDGDKGVPREV 274
Query: 496 LYDLQRTSNLTITSPFKINPNTGTVSVAE--SPILEGRHA-----LFVEASDQPANPSER 548
Y L N T F ++ TG + ++ + + H L + A + E
Sbjct: 275 TYGLISEGN-PFTPFFNVSETTGEIILSRPLEELTKITHVGAPIVLKIVAEEIRTTRDEP 333
Query: 549 RYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG-----QIRVNDAFEQ 603
VV + + G GN P P F Y W+ N GT + RV D
Sbjct: 334 PAQATVVELGLLLGEPGNSP--PYFENDNYMAWIDENAEPGTIIVFSDAYSTRVKDEDIG 391
Query: 604 NDVSYDLLHGYEEG---VPFAVEERSG--VITVVD----DLSRYNRPMYDFEAVALQENA 654
+ L G + AV ER+ VITV D D ++ + A +
Sbjct: 392 KAGVFALKLENNNGTFEISPAVAERNANFVITVRDNSMIDYEKFKSLRFKIVAQEVGPAT 451
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQIFHTNMSSIYGNGT 713
NLS T+ + DVND + + EN SAG + Q+ T++ +
Sbjct: 452 NLSTSVPVTIFLRDVNDNPPTFDVPVYEVTL---SENASAGTRVVQVHATDIDA---GAF 505
Query: 714 GNVRFL-IANQQDVTDDIAIAEDGTIFTQKP--LDREKRDVYRMTVIAEFNKGVISGAGI 770
G +++ I ++ + G I LDRE+ +TV A G GI
Sbjct: 506 GRIQYTKIIGDGSAAFEMN-PDSGMIAVSMGSILDREQTAKLELTVEARDEDGR-GMRGI 563
Query: 771 YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGTNALFMYTL 829
+ + I D NDN PVF+ A YE F++ NS++ T M IIKA D D E N + Y +
Sbjct: 564 AALMVNILDVNDNAPVFDKAIYE-FLL-NSEL-TNFTMPAIIKAVDTDAEPPNNVVRYEI 620
Query: 830 -FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
G + F ++E TG + + + +++ +K + A D+
Sbjct: 621 VHGNYENKFQLNEETGEL-MLREPINKARKARHNRRRRAEDS 661
Score = 69.7 bits (163), Expect = 6e-10
Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG--EFTYQLDDPK 349
V I L D+NDN P F+V Y +++ EN G V+QV ATD D G G ++T + D
Sbjct: 459 VTIFLRDVNDNPPTFDVPVYEVTLSENASAGTRVVQVHATDIDAGAFGRIQYTKIIGDGS 518
Query: 350 GAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
AF ++P SG + V ++LDRE + L + V A++
Sbjct: 519 AAFEMNPDSGMIAVSMGSILDREQTAKLELTVEARD 554
Score = 65.7 bits (153), Expect = 9e-09
Identities = 67/224 (29%), Positives = 96/224 (42%), Gaps = 20/224 (8%)
Query: 940 IPENIPIGTTIIKLNAL-----DLDSGLNG--QIRYEFNSEVYIPPSKLSADALEVKRYF 992
I EN GT I+ +A D D G G ++ E N+ + ++S E F
Sbjct: 365 IDENAEPGTIIVFSDAYSTRVKDEDIGKAGVFALKLENNNGTF----EISPAVAERNANF 420
Query: 993 VINERHGHVIVARSLPPESEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVFKKTW 1049
VI R +I R I A + G NL+ ++ V +F++DVND+ P F
Sbjct: 421 VITVRDNSMIDYEKF---KSLRFKIVAQEVGPATNLSTSVPVTIFLRDVNDNPPTFDVPV 477
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN--GE 1107
Y + E + +V ATD D G + Y D FE++P +G+++V+
Sbjct: 478 YEVTLSENASAGTRVVQVHATDIDAGAFGRIQYTKIIGDGSAAFEMNPDSGMIAVSMGSI 537
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
LDRE K LTV ARD DVNDN+P F
Sbjct: 538 LDREQTAKLELTVEARDE-DGRGMRGIAALMVNILDVNDNAPVF 580
Score = 64.5 bits (150), Expect = 2e-08
Identities = 64/230 (27%), Positives = 109/230 (47%), Gaps = 23/230 (10%)
Query: 439 LMSFVNVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
L + V V + L D NDN P F VP +YE ++ NA GT + +V A D D G G + Y
Sbjct: 453 LSTSVPVTIFLRDVNDNPPTFDVP--VYEVTLSENASAGTRVVQVHATDIDAGAFGRIQY 510
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAESPILE----GRHALFVEASDQPANPSERRYSLA 553
++ F++NP++G ++V+ IL+ + L VEA D+ +L
Sbjct: 511 TKIIGDG---SAAFEMNPDSGMIAVSMGSILDREQTAKLELTVEARDEDGRGMRGIAALM 567
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ---NDVSYDL 610
V ++V + P F A YEF + S + T I+ D + N V Y++
Sbjct: 568 VNILDV-------NDNAPVFDKAIYEFLLNSELTNFTMPAIIKAVDTDAEPPNNVVRYEI 620
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT 660
+HG E F + E +G + + + +++ + ++ A E++ L I+T
Sbjct: 621 VHGNYEN-KFQLNEETGELMLREPINKARKARHNRRRRA--EDSPLFILT 667
Score = 62.5 bits (145), Expect = 9e-08
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 18/190 (9%)
Query: 218 IHAIDQDLGVGATLRYELIS-GND-RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+HA D D GV + Y LIS GN F++ G + L + L+ + VL+
Sbjct: 261 VHAEDGDKGVPREVTYGLISEGNPFTPFFNVSETTGEIILSRPLEELTKITHVGAPIVLK 320
Query: 276 VQASQLNNPLKTAQAR---VEIELL--DLNDNLPEFEVDFYNISIVENLPNGFSVL---- 326
+ A ++ A+ VE+ LL + ++ P FE D Y I EN G ++
Sbjct: 321 IVAEEIRTTRDEPPAQATVVELGLLLGEPGNSPPYFENDNYMAWIDENAEPGTIIVFSDA 380
Query: 327 -QVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGW------LTVRNQTVLDREAHSSLRM 379
D+D G+ G F +L++ G F I P +TVR+ +++D E SLR
Sbjct: 381 YSTRVKDEDIGKAGVFALKLENNNGTFEISPAVAERNANFVITVRDNSMIDYEKFKSLRF 440
Query: 380 KVYAKETNPS 389
K+ A+E P+
Sbjct: 441 KIVAQEVGPA 450
Score = 52.8 bits (121), Expect = 7e-05
Identities = 54/209 (25%), Positives = 94/209 (44%), Gaps = 29/209 (13%)
Query: 923 PKNKFALDVDQLGPLFLIP-------ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVY 975
P F DV+ P F +P EN GT +++++A D+D+G G+I+Y
Sbjct: 458 PVTIFLRDVNDNPPTFDVPVYEVTLSENASAGTRVVQVHATDIDAGAFGRIQY------- 510
Query: 976 IPPSKLSADALEVKRYFVINERHGHVIVARS--LPPESEFRLNISAL----DGGNLNDNI 1029
+K+ D F +N G + V+ L E +L ++ DG +
Sbjct: 511 ---TKIIGDGSAA---FEMNPDSGMIAVSMGSILDREQTAKLELTVEARDEDGRGMRGIA 564
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNF--NVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
++ V + DVND+ PVF K Y F N E +T + K TDA+ N + Y I
Sbjct: 565 ALMVNILDVNDNAPVFDKAIYEFLLNSELTNFTMPAIIKAVDTDAEPPNNV-VRYEIVHG 623
Query: 1088 DTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ + F+++ TG L + +++ + ++
Sbjct: 624 NYENKFQLNEETGELMLREPINKARKARH 652
Score = 48.8 bits (111), Expect = 0.001
Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 6/166 (3%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
+HA D D G ++Y I G+ F ++ +G + + LD E Q L V+
Sbjct: 495 VHATDIDAGAFGRIQYTKIIGDGSAAFEMNPDSGMIAVSMGSILDRE---QTAKLELTVE 551
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QG 336
A + A + + +LD+NDN P F+ Y + L N + A D D +
Sbjct: 552 ARDEDGRGMRGIAALMVNILDVNDNAPVFDKAIYEFLLNSELTNFTMPAIIKAVDTDAEP 611
Query: 337 ENGEFTYQL--DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMK 380
N Y++ + + F ++ +G L +R R+A + R +
Sbjct: 612 PNNVVRYEIVHGNYENKFQLNEETGELMLREPINKARKARHNRRRR 657
Score = 46.0 bits (104), Expect = 0.008
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
A + ++ + + + ++PP FE+ Y +I EN++ GT I + DE ++
Sbjct: 337 ATVVELGLLLGEPGNSPPYFENDNYMAWIDENAEPGTIIVFSDAYSTRVKDEDIGKAGVF 396
Query: 828 TLFGEGKE-MFDV-----DENTGVVKFIGDS--LDREKKIMYKLSLVARDTG---GLSSE 876
L E F++ + N V + D+ +D EK + +VA++ G LS+
Sbjct: 397 ALKLENNNGTFEISPAVAERNANFVITVRDNSMIDYEKFKSLRFKIVAQEVGPATNLSTS 456
Query: 877 AELIIMIGDENDNKPEFN 894
+ I + D NDN P F+
Sbjct: 457 VPVTIFLRDVNDNPPTFD 474
>UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3;
n=1; Xenopus tropicalis|Rep: FAT tumor suppressor
homolog 3 - Xenopus tropicalis
Length = 978
Score = 84.6 bits (200), Expect = 2e-14
Identities = 55/163 (33%), Positives = 87/163 (53%), Gaps = 7/163 (4%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G I ++PLDRE + Y +TV A V++ + + VTI + D NDNPP+FE Y
Sbjct: 26 GIIILEQPLDRELQSSYNITVKASDLSPVLTLSSLAFVTITVLDVNDNPPIFERRDYWVT 85
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGVVKFIGDSLD 854
+ E++ +GT++ + A D GTNA +Y++ G F ++ TG + + ++LD
Sbjct: 86 VAEDTTLGTKVLS---VFAASKDIGTNAEILYSIRSGNEHAQFFINPKTGAISVV-NTLD 141
Query: 855 REKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
E + L + A D G LS+ + I + D NDN P F+Q
Sbjct: 142 YENCKHFYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQ 184
Score = 72.9 bits (171), Expect = 6e-11
Identities = 78/302 (25%), Positives = 124/302 (41%), Gaps = 20/302 (6%)
Query: 991 YFVINERHGHVIVARSLPPE--SEFRLNISALDGG---NLNDNISVRVFVKDVNDHFPVF 1045
+F ++ G +I+ + L E S + + + A D L+ V + V DVND+ P+F
Sbjct: 18 HFAVDMSSGIIILEQPLDRELQSSYNITVKASDLSPVLTLSSLAFVTITVLDVNDNPPIF 77
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
++ Y V E + V A D G NA + Y I+ + F I+P TG +SV
Sbjct: 78 ERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIRSGNEHAQFFINPKTGAISVV 137
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF--YAFDELLEWKHP 1163
LD E + L V A D G DVNDN+P F + ++
Sbjct: 138 NTLDYENCKHFYLVVEATDGG-SPSLSAVTTVNINLTDVNDNAPVFSQEVYSAVISEDAS 196
Query: 1164 EADELSNHNFESVMM--IPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQR 1221
D + + S + + + A + TT A+ +G YSL
Sbjct: 197 VGDSVVMVSVTSSISNGLFYFAANFNHFFLLFTTPAEGRQRGASARWKVSG---YSL--L 251
Query: 1222 KNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNL 1281
++ G P+LSST + + ++DV D + P F Y I+EN +V L +
Sbjct: 252 VQARDSGAPALSSTVTVNIDISDVND-----NSPQFTPANYSAVIQENKPVGTSIVQLVV 306
Query: 1282 TE 1283
T+
Sbjct: 307 TD 308
Score = 68.9 bits (161), Expect = 1e-09
Identities = 109/420 (25%), Positives = 181/420 (43%), Gaps = 42/420 (10%)
Query: 490 GQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPS 546
G N V+Y L +++ F ++ ++G + + E P+ L+ + + V+ASD +P
Sbjct: 2 GINRKVVYSLVDSAD----GHFAVDMSSGII-ILEQPLDRELQSSYNITVKASD--LSPV 54
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQN 604
SLA VTI V + P P F Y V + +GT V + D
Sbjct: 55 LTLSSLAFVTITVL--DVNDNP--PIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNA 110
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNAT 663
++ Y + G E F + ++G I+VV+ L N + A + +LS VT
Sbjct: 111 EILYSIRSGNEHA-QFFINPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVN 169
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQ-IFHTNMSSIYGNGTGNVRFLIAN 722
+++ DVND V + +S +I S A++G + +++S NG + + AN
Sbjct: 170 INLTDVNDNAPVFSQEVYSAVI------SEDASVGDSVVMVSVTSSISNG---LFYFAAN 220
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+G + R K Y + V A + G + + V I I D ND
Sbjct: 221 FNHFFLLFTTPAEGR--QRGASARWKVSGYSLLVQAR-DSGAPALSSTVTVNIDISDVND 277
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLF--GEGKEMFDV 839
N P F A Y I EN +GT I + TD D N F +T+ EG E F +
Sbjct: 278 NSPQFTPANYSAVIQENKPVGTSIVQ---LVVTDKDSFHNGPPFEFTIISGNEGGE-FLL 333
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
D+ +GV++ + L + +D+G L+S++ L I + +E+ +KP +E
Sbjct: 334 DQ-SGVLR-SAVVFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPLE 391
Score = 67.3 bits (157), Expect = 3e-09
Identities = 46/143 (32%), Positives = 76/143 (53%), Gaps = 9/143 (6%)
Query: 226 GVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL 285
G+ + Y L+ D F++D +G + LE+ LD + + +++ + V+AS L+ L
Sbjct: 2 GINRKVVYSLVDSADGH-FAVDMSSGIIILEQPLDRELQ-----SSYNITVKASDLSPVL 55
Query: 286 KTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ 344
+ A V I +LD+NDN P FE Y +++ E+ G VL V A KD G N E Y
Sbjct: 56 TLSSLAFVTITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYS 115
Query: 345 L--DDPKGAFSIDPRSGWLTVRN 365
+ + F I+P++G ++V N
Sbjct: 116 IRSGNEHAQFFINPKTGAISVVN 138
Score = 66.5 bits (155), Expect = 5e-09
Identities = 87/313 (27%), Positives = 131/313 (41%), Gaps = 58/313 (18%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S+ VT+ + DVNDN PIF Y VTV E T G K A
Sbjct: 57 LSSLAFVTITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAAS------------- 103
Query: 137 GLTIFKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKE 196
KDI N+++ YSI SGN+ F + + ++ LDY+ K
Sbjct: 104 -----KDIGT---------NAEILYSIRSGNEHAQFFINPKTGAISVV-NTLDYE-NCKH 147
Query: 197 FQLVIMAS--GKRIHKEI---------------LFPEPIHA--IDQDLGVG-ATLRYELI 236
F LV+ A+ G + +F + +++ I +D VG + + +
Sbjct: 148 FYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQEVYSAVISEDASVGDSVVMVSVT 207
Query: 237 SGNDRKLFSLDSVNGSLFL-----EKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQAR 291
S LF + FL + A + + + L VQA P ++
Sbjct: 208 SSISNGLFYFAANFNHFFLLFTTPAEGRQRGASARWKVSGYSLLVQARDSGAPALSSTVT 267
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENG---EFTYQLDDP 348
V I++ D+NDN P+F Y+ I EN P G S++Q++ TDKD NG EFT +
Sbjct: 268 VNIDISDVNDNSPQFTPANYSAVIQENKPVGTSIVQLVVTDKDSFHNGPPFEFTIISGNE 327
Query: 349 KGAFSIDPRSGWL 361
G F +D +SG L
Sbjct: 328 GGEFLLD-QSGVL 339
Score = 63.3 bits (147), Expect = 5e-08
Identities = 107/437 (24%), Positives = 170/437 (38%), Gaps = 39/437 (8%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L S V +T+LD NDN P+F + Y ++ + +GT + V A D+G N +LY
Sbjct: 57 LSSLAFVTITVLDVNDNPPIFERRD-YWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYS 115
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEG-RH-ALFVEASDQPANPSERRYSLAVVT 556
+ R+ N + F INP TG +SV + E +H L VEA+D +PS AV T
Sbjct: 116 I-RSGN--EHAQFFINPKTGAISVVNTLDYENCKHFYLVVEATD-GGSPS----LSAVTT 167
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ + T N + P F Y + + +G SV + V + N + Y +
Sbjct: 168 VNINL-TDVN-DNAPVFSQEVYSAVISEDASVGDSVVMVSVTSSI-SNGLFYFAANFNHF 224
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVNDERGV 675
+ F +R+ Y A A LS + + DVND
Sbjct: 225 FLLFTTPAEG---RQRGASARWKVSGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQ 281
Query: 676 LLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ--QDVTDDIAI 732
+S +I +EN G +I Q+ T+ S + + N+ + + D +
Sbjct: 282 FTPANYSAVI---QENKPVGTSIVQLVVTDKDSFHNGPPFEFTIISGNEGGEFLLDQSGV 338
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
+F D V + + K ++ + + IE+ P Y
Sbjct: 339 LRSAVVFQHTISDEHLLCVQ----VKDSGKPALTSQSFLHIRV-IEESVHKPSAIPLEVY 393
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDS 852
ME+ G I I ATD D + Y L E K +F V+ + G + +G
Sbjct: 394 I-VTMEDDFPGGVI---GKIHATDQD--IYDVLSYNLKSEQKSLFKVNNHDGKLIALG-G 446
Query: 853 LDREKKIMYKLSLVARD 869
LD K Y L++ D
Sbjct: 447 LDGGK---YTLNVSVND 460
Score = 56.4 bits (130), Expect = 6e-06
Identities = 92/363 (25%), Positives = 147/363 (40%), Gaps = 63/363 (17%)
Query: 929 LDVDQLGPLF-------LIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKL 981
LDV+ P+F + E+ +GT ++ + A D G N +I Y S
Sbjct: 68 LDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIRS--------- 118
Query: 982 SADALEVKRYFVINERHGHVIVARSLPPES--EFRLNISALDGG--NLNDNISVRVFVKD 1037
E ++F IN + G + V +L E+ F L + A DGG +L+ +V + + D
Sbjct: 119 ---GNEHAQFF-INPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTD 174
Query: 1038 VNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP 1097
VND+ PVF + Y+ + E + V T + + L YF + +P
Sbjct: 175 VNDNAPVFSQEVYSAVISEDASVGDSVVMVSVTSS---ISNGLFYFAANFNHFFLLFTTP 231
Query: 1098 LTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDEL 1157
G G R Y L V ARD+G DVNDNSP+F
Sbjct: 232 AEG--RQRGASARWKVSGYSLLVQARDSG-APALSSTVTVNIDISDVNDNSPQF------ 282
Query: 1158 LEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+ N+ +V I+EN P+GT++ ++ D D NG
Sbjct: 283 -----------TPANYSAV---------IQENKPVGTSIVQLVVTDKDSFHNGPPFEFTI 322
Query: 1218 LPQRKNQQNLGLPS--LSSTAILMVTVAD---VPDEVEMSDKPVFISR-YYELE-IEENV 1270
+ + + L S L S + T++D + +V+ S KP S+ + + IEE+V
Sbjct: 323 ISGNEGGEFLLDQSGVLRSAVVFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESV 382
Query: 1271 NAP 1273
+ P
Sbjct: 383 HKP 385
>UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01; n=4;
Gallus gallus|Rep: Cadherin-related neuronal receptor c01
- Gallus gallus (Chicken)
Length = 948
Score = 84.6 bits (200), Expect = 2e-14
Identities = 75/254 (29%), Positives = 116/254 (45%), Gaps = 22/254 (8%)
Query: 918 IIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIP 977
I+ V N A + +Q + EN P GT +++++A DLD G NG++RY F+
Sbjct: 476 IVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFS------ 529
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESE-FRLNISALDGG--NLNDNISVRVF 1034
+A A ++++ F+I+ G V V+ L + + I A D G L+ + V
Sbjct: 530 ----NATAADLQQMFLIHPHTGEVTVSGDLAVQRPLLEMLIEARDKGAFALSSTAKLLVE 585
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ DVN+H P + + E V+ + D D G+N +T I +LPF+
Sbjct: 586 ITDVNNHGPEITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQI---PDNLPFQ 642
Query: 1095 ISP-LTGVLSV--NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ P L S+ +G LDRE Y +T+ A D G DVNDN P F
Sbjct: 643 LKPSLENYYSLITSGLLDRELISGYNITITATDLG-SPPITTQQTLWVQISDVNDNPPVF 701
Query: 1152 YA--FDELLEWKHP 1163
A FD +E +P
Sbjct: 702 AADTFDVFVEENNP 715
Score = 81.4 bits (192), Expect = 2e-13
Identities = 62/192 (32%), Positives = 103/192 (53%), Gaps = 17/192 (8%)
Query: 712 GTGNVRFLIANQQDVTD-DIAIAEDGTIFTQ----KPLDREKRDVYRMTVIAEFNKGVIS 766
GT V+ I N + ++ + DG+++ + K LDRE++ +R+ +IAE + G
Sbjct: 410 GTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKKALDREQQATHRLVLIAE-DGGDPP 468
Query: 767 GAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFM 826
+G V + + D NDN P FE + Y ++ENS GT + + ATD DEG N
Sbjct: 469 RSGDVPVIVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVR---VHATDLDEGPNGEVR 525
Query: 827 YTL----FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELI 880
Y+ + ++MF + +TG V GD L ++ ++ ++ + ARD G LSS A+L+
Sbjct: 526 YSFSNATAADLQQMFLIHPHTGEVTVSGD-LAVQRPLL-EMLIEARDKGAFALSSTAKLL 583
Query: 881 IMIGDENDNKPE 892
+ I D N++ PE
Sbjct: 584 VEITDVNNHGPE 595
Score = 73.7 bits (173), Expect = 3e-11
Identities = 101/431 (23%), Positives = 165/431 (38%), Gaps = 30/431 (6%)
Query: 408 LETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEF 467
L N P+++ + T N E E + +E +LD NDN+P F P + Y
Sbjct: 331 LSVNEPIDREQLC--ELKSTCLLNYELVLENPLELYRMEFKVLDVNDNSPSF-PLSEYRV 387
Query: 468 SMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPI 527
S+ G A D D G NG+ Y L + + + + + V + +
Sbjct: 388 SVPEFLSPGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKKAL 447
Query: 528 ---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGS 584
+ H L + A D P + V ++ T N P+F + Y V
Sbjct: 448 DREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLD----TNDN---APEFEQSVYRASVLE 500
Query: 585 NVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVP--FAVEERSGVITVVDDLSRYNR 640
N GT V ++ D E +V Y + + F + +G +TV DL+ R
Sbjct: 501 NSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQQMFLIHPHTGEVTVSGDLA-VQR 559
Query: 641 PMYDFEAVALQENA-NLSIVTNATVHVVDVNDE-RGVLLKGAHSPIIFHVKENSAGAAIG 698
P+ + A + A LS V + DVN+ + + +PI ++ G I
Sbjct: 560 PLLEMLIEARDKGAFALSSTAKLLVEITDVNNHGPEITIASLSNPI---PEDAVPGTVIA 616
Query: 699 QIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIA 758
+ + G V I + ++ ++ T LDRE Y +T+ A
Sbjct: 617 LLSIVDKDP---GENGKVTCQIPDNLPFQLKPSLENYYSLITSGLLDRELISGYNITITA 673
Query: 759 EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD 818
+ G + + I D NDNPPVF T++ F+ EN+ +G + + A+D D
Sbjct: 674 T-DLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQ---VSASDLD 729
Query: 819 EGTNALFMYTL 829
G N Y L
Sbjct: 730 IGENGQISYIL 740
Score = 73.7 bits (173), Expect = 3e-11
Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 219 HAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
+A D D G Y L L +GS++ E L + QA T L + A
Sbjct: 403 NAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKKALDREQQA-THRLVLIA 461
Query: 279 SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+P ++ V + +LD NDN PEFE Y S++EN P+G V++V ATD D+G N
Sbjct: 462 EDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPN 521
Query: 339 GEFTYQLDDPKGA-----FSIDPRSGWLTVRNQTVLDR 371
GE Y + A F I P +G +TV + R
Sbjct: 522 GEVRYSFSNATAADLQQMFLIHPHTGEVTVSGDLAVQR 559
Score = 67.3 bits (157), Expect = 3e-09
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 9/169 (5%)
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
A G + +P+DRE+ + T + + + + +Y++ + D NDN P F + Y
Sbjct: 326 ATTGVLSVNEPIDREQLCELKSTCLLNYELVLENPLELYRMEFKVLDVNDNSPSFPLSEY 385
Query: 793 EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDV----DENTGVVKF 848
+ E G + N A D DEGTN + Y L + ++ D +
Sbjct: 386 RVSVPEFLSPGARFALPN---AQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELV 442
Query: 849 IGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
+ +LDRE++ ++L L+A D G S + +I+ + D NDN PEF Q
Sbjct: 443 LKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQ 491
Score = 67.3 bits (157), Expect = 3e-09
Identities = 99/416 (23%), Positives = 171/416 (41%), Gaps = 39/416 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+PE + G NA DLD G NG Y N + + V V+ +
Sbjct: 389 VPEFLSPGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKK--- 445
Query: 1000 HVIVARSLPPESEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
A ++ RL + A DGG+ + ++ V V V D ND+ P F+++ Y +V E
Sbjct: 446 ----ALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRASVLEN 501
Query: 1058 QYTRRVLGKVDATDADFGQNANLTY-FIQPSDTDLP--FEISPLTGVLSVNGELDRETED 1114
+ ++ +V ATD D G N + Y F + DL F I P TG ++V+G+L +
Sbjct: 502 SPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQQMFLIHPHTGEVTVSGDLAVQRPL 561
Query: 1115 KYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFE 1174
+L + ARD G DVN++ P+ + +P ++
Sbjct: 562 LEML-IEARDKG-AFALSSTAKLLVEITDVNNHGPEI----TIASLSNPIPEDAVPGTV- 614
Query: 1175 SVMMIPVYKATIEENAPIGTTVAKVFAND-TDFIGNGNGLILYSLPQRK---------NQ 1224
+ ++ + EN + + + N LI L R+
Sbjct: 615 -IALLSIVDKDPGENGKVTCQIPDNLPFQLKPSLENYYSLITSGLLDRELISGYNITITA 673
Query: 1225 QNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPVELVSLNLT 1282
+LG P +++ L V ++DV D + PVF + +++ +EEN + A + VS +
Sbjct: 674 TDLGSPPITTQQTLWVQISDVND-----NPPVFAADTFDVFVEENNPLGAFLYQVSASDL 728
Query: 1283 EHYENFKMRYYILNENDTDIRRTFVIDPR--NGTLYLVRSPDREVKDTYEVIVRAE 1336
+ EN ++ Y + N T + NG++Y R+ D E ++ V A+
Sbjct: 729 DIGENGQISYILRNSTVAGSALTSFLSVSLVNGSIYAKRAFDFEQLRSFHFQVEAK 784
Score = 61.7 bits (143), Expect = 2e-07
Identities = 48/174 (27%), Positives = 91/174 (52%), Gaps = 14/174 (8%)
Query: 221 IDQDLGVGATL----RYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ +DLG+ A ++ +I G+ ++ F++++ G L + + +D + L++ T +L
Sbjct: 295 VAKDLGINAAALSARKFRMIIGSSKQYFNINATTGVLSVNEPIDREQLCELKS-TCLLNY 353
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
+ L NPL+ R+E ++LD+NDN P F + Y +S+ E L G A D D+G
Sbjct: 354 ELV-LENPLELY--RMEFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEG 410
Query: 337 ENGEFTYQLDDPKGAFSIDPR-----SGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y L +P F ++ + S + + + LDRE ++ R+ + A++
Sbjct: 411 TNGVQNYIL-NPDEHFHLEMQMRGDGSVYPELVLKKALDREQQATHRLVLIAED 463
Score = 61.7 bits (143), Expect = 2e-07
Identities = 84/333 (25%), Positives = 147/333 (44%), Gaps = 33/333 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
V V VT+LD NDN P F S +Y S+ N+ GT++ +V A D D G NG V Y
Sbjct: 473 VPVIVTVLDTNDNAPEFEQS-VYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNA 531
Query: 503 SNLTITSPFKINPNTGTVSVA-----ESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ + F I+P+TG V+V+ + P+LE + +EA D+ A S A + +
Sbjct: 532 TAADLQQMFLIHPHTGEVTVSGDLAVQRPLLE----MLIEARDKGAFALS---STAKLLV 584
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYE 615
E+T + P+I A + + GT + + + D E V+ +
Sbjct: 585 EIT-DVNNHGPEITI---ASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIPDNLP 640
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVNDER 673
+ ++E +IT L R Y+ + + + I T T V + DVND
Sbjct: 641 FQLKPSLENYYSLIT-SGLLDRELISGYNI-TITATDLGSPPITTQQTLWVQISDVNDNP 698
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ----QDVTDD 729
V A + +F + N GA + Q+ + S + G + +++ N +T
Sbjct: 699 PVF--AADTFDVFVEENNPLGAFLYQV---SASDLDIGENGQISYILRNSTVAGSALTSF 753
Query: 730 IAIA-EDGTIFTQKPLDREKRDVYRMTVIAEFN 761
++++ +G+I+ ++ D E+ + V A+ N
Sbjct: 754 LSVSLVNGSIYAKRAFDFEQLRSFHFQVEAKDN 786
Score = 60.5 bits (140), Expect = 3e-07
Identities = 74/285 (25%), Positives = 121/285 (42%), Gaps = 31/285 (10%)
Query: 78 SAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPI--GPSLTIPLTVP 135
S + V V + D NDN P F + Y +V E +P+G + GP+ + +
Sbjct: 470 SGDVPVIVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFS 529
Query: 136 RGLTIFKDIRAFDRDKPNTPNSDVHYSI----------VSGNDDGHFALESSHKPVLLLR 185
D++ P+T V + + D G FAL S+ K LL
Sbjct: 530 NATAA--DLQQMFLIHPHTGEVTVSGDLAVQRPLLEMLIEARDKGAFALSSTAK---LLV 584
Query: 186 KVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHA----IDQDLGVGATLRYELISGNDR 241
++ D + E + +AS E P + A +D+D G + ++ D
Sbjct: 585 EITDVNNHGPE---ITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQI---PDN 638
Query: 242 KLFSLD-SVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLN 300
F L S+ L LD E + + + + A+ L +P T Q + +++ D+N
Sbjct: 639 LPFQLKPSLENYYSLITSGLLDRE---LISGYNITITATDLGSPPITTQQTLWVQISDVN 695
Query: 301 DNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
DN P F D +++ + EN P G + QV A+D D GENG+ +Y L
Sbjct: 696 DNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYIL 740
Score = 55.6 bits (128), Expect = 1e-05
Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 21/225 (9%)
Query: 910 LNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYE 969
L+ TA ++E+ N ++ IPE+ GT I L+ +D D G NG++ +
Sbjct: 576 LSSTAKL-LVEITDVNNHGPEITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQ 634
Query: 970 FNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGN--LND 1027
+ P +L +LE Y +I ++ R L S + + I+A D G+ +
Sbjct: 635 IPDNL---PFQLKP-SLE-NYYSLITSG----LLDRELI--SGYNITITATDLGSPPITT 683
Query: 1028 NISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS 1087
++ V + DVND+ PVF ++ VEE L +V A+D D G+N ++Y ++ S
Sbjct: 684 QQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYILRNS 743
Query: 1088 DTDLPFEISPLTGVLSVNGEL------DRETEDKYILTVVARDNG 1126
T ++ V VNG + D E + V A+DNG
Sbjct: 744 -TVAGSALTSFLSVSLVNGSIYAKRAFDFEQLRSFHFQVEAKDNG 787
Score = 52.0 bits (119), Expect = 1e-04
Identities = 53/228 (23%), Positives = 95/228 (41%), Gaps = 8/228 (3%)
Query: 168 DDGHFALESSHKPVLLLRKVLDYDAGDKEF-QLVIMASGKRIHKEILFPEPIHAIDQDLG 226
+DG S PV++ VLD + EF Q V AS +HA D D G
Sbjct: 462 EDGGDPPRSGDVPVIVT--VLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEG 519
Query: 227 VGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK 286
+RY + L + ++ E+ + + +Q + ++A
Sbjct: 520 PNGEVRYSFSNATAADLQQMFLIHPHT---GEVTVSGDLAVQRPLLEMLIEARDKGAFAL 576
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD 346
++ A++ +E+ D+N++ PE + + I E+ G + + DKD GENG+ T Q+
Sbjct: 577 SSTAKLLVEITDVNNHGPEITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIP 636
Query: 347 DPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGT 393
D F + P + ++ +LDRE S + + A + + T
Sbjct: 637 D-NLPFQLKPSLENYYSLITSGLLDRELISGYNITITATDLGSPPITT 683
Score = 43.6 bits (98), Expect = 0.043
Identities = 63/238 (26%), Positives = 92/238 (38%), Gaps = 38/238 (15%)
Query: 989 KRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVF-----VKDVNDHFP 1043
K+YF IN G + V + E L + L L + ++ V DVND+ P
Sbjct: 319 KQYFNINATTGVLSVNEPIDREQLCELKSTCLLNYELVLENPLELYRMEFKVLDVNDNSP 378
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSD-TDLPFEISPLTGV- 1101
F + Y +V E +A D D G N Y + P + L ++ V
Sbjct: 379 SFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVY 438
Query: 1102 --LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLE 1159
L + LDRE + + L ++A D G D NDN+P+F
Sbjct: 439 PELVLKKALDREQQATHRLVLIAEDGG-DPPRSGDVPVIVTVLDTNDNAPEFE------- 490
Query: 1160 WKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYS 1217
+SV Y+A++ EN+P GT V +V A D D NG + YS
Sbjct: 491 --------------QSV-----YRASVLENSPSGTLVVRVHATDLD--EGPNGEVRYS 527
Score = 38.7 bits (86), Expect = 1.2
Identities = 54/234 (23%), Positives = 92/234 (39%), Gaps = 13/234 (5%)
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
V V+D ND + + + ENS +G + ++ T++ NG F A
Sbjct: 477 VTVLDTNDNAPEFEQSVYRASVL---ENSPSGTLVVRVHATDLDE-GPNGEVRYSFSNAT 532
Query: 723 QQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEN 781
D+ I G + L +R + M + A +KG + + ++ + I D N
Sbjct: 533 AADLQQMFLIHPHTGEVTVSGDL-AVQRPLLEMLIEAR-DKGAFALSSTAKLLVEITDVN 590
Query: 782 DNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDE 841
++ P A+ I E++ GT I + +I+ D D G N +
Sbjct: 591 NHGPEITIASLSNPIPEDAVPGTVIALLSIV---DKDPGENGKVTCQIPDNLPFQLKPSL 647
Query: 842 NTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEF 893
LDRE Y +++ A D G ++++ L + I D NDN P F
Sbjct: 648 ENYYSLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQISDVNDNPPVF 701
>UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1;
Takifugu rubripes|Rep: Cadherin-7 precursor. - Takifugu
rubripes
Length = 784
Score = 84.2 bits (199), Expect = 2e-14
Identities = 83/287 (28%), Positives = 129/287 (44%), Gaps = 24/287 (8%)
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
G G VR+++ + + G I + LDRE++ Y + A
Sbjct: 37 GDGQVRYVLTGEGAASIFSIDESTGDIHATRRLDREQQAYYTLRAQARNRDTNRLVEPES 96
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADE---GTNALFMYT 828
Q I ++D NDN P F Y + E S +GT + + ATDAD+ G +A MY+
Sbjct: 97 QFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVV---TVVATDADDPTYGNSARLMYS 153
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIG 884
+ +G+ F V+ TGVV+ LDRE + + L + A+D GGLS + +++
Sbjct: 154 IL-QGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILT 212
Query: 885 DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPK-------NKFALDVDQLGPL 937
D NDN P F + V RE++L T I V P + LD D LG +
Sbjct: 213 DVNDNPPHFPRRSYQFSV---RESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLG-I 268
Query: 938 FLIPENIPIGTTIIKLNA-LDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
F I + +I L+ LD ++ + +R E S +Y+ LS+
Sbjct: 269 FSITTDSHTQEGLITLHKNLDFETKSSYMLRVE-ASNLYVDARFLSS 314
Score = 69.7 bits (163), Expect = 6e-10
Identities = 69/225 (30%), Positives = 109/225 (48%), Gaps = 37/225 (16%)
Query: 921 VKPKNKFAL---DVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
V+P+++F + DV+ P FL + E P+GT+++ + A D D G
Sbjct: 92 VEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYG------ 145
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPP-ESEFR----LNISALDG--- 1022
NS ++L L+ + YF + + G +V +LP + E R L + A D
Sbjct: 146 NS------ARLMYSILQGQPYFSVEPKTG--VVRTALPDLDREVRDSHLLVVQAKDMIGQ 197
Query: 1023 -GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLT 1081
G L+ + SV V + DVND+ P F + Y F+V E++ V+ K+ A D D G NA L
Sbjct: 198 IGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELD 257
Query: 1082 YFIQPSDTDLPFEIS----PLTGVLSVNGELDRETEDKYILTVVA 1122
Y I D F I+ G+++++ LD ET+ Y+L V A
Sbjct: 258 YRILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEA 302
Score = 67.3 bits (157), Expect = 3e-09
Identities = 55/178 (30%), Positives = 86/178 (48%), Gaps = 14/178 (7%)
Query: 213 LFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
L+ +H+ D D G G +RY L +FS+D G + + LD + Q +
Sbjct: 25 LYVGKLHS-DVDKGDGQ-VRYVLTGEGAASIFSIDESTGDIHATRRLDRE-----QQAYY 77
Query: 273 VLQVQASQLN-NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
L+ QA + N L +++ I++ D+NDN P+F Y + E P G SV+ V+AT
Sbjct: 78 TLRAQARNRDTNRLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVAT 137
Query: 332 DKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV-LDREAHSSLRMKVYAKE 385
D D G + Y + + FS++P++G VR LDRE S + V AK+
Sbjct: 138 DADDPTYGNSARLMYSILQGQPYFSVEPKTG--VVRTALPDLDREVRDSHLLVVQAKD 193
Score = 58.4 bits (135), Expect = 1e-06
Identities = 54/171 (31%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVR------VFVKDVNDHFPVF 1045
F I+E G + R L E + + A N + N V + V+DVND+ P F
Sbjct: 54 FSIDESTGDIHATRRLDREQQAYYTLRA-QARNRDTNRLVEPESQFIIKVQDVNDNEPKF 112
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVL 1102
Y V E + V ATDAD +G +A L Y I F + P TGV+
Sbjct: 113 LDGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSILQGQPY--FSVEPKTGVV 170
Query: 1103 -SVNGELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ +LDRE D ++L V A+D G DVNDN P F
Sbjct: 171 RTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHF 221
Score = 55.6 bits (128), Expect = 1e-05
Identities = 121/504 (24%), Positives = 199/504 (39%), Gaps = 84/504 (16%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P F+ Y + + VGT + V A D P G + ++Y + +
Sbjct: 100 IKVQDVNDNEPKFLDGP-YTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSILQGQ 158
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
F + P TG V A + + H L V+A D S +V I
Sbjct: 159 PY-----FSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVI--L 211
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGV 618
N P P Y+F V + + T V +IR D E ++ Y +L G G+
Sbjct: 212 TDVNDNPPHFPR---RSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLGI 268
Query: 619 PFAVEERS----GVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERG 674
F++ S G+IT+ +L + Y A + +++ DV R
Sbjct: 269 -FSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFS--DVATVR- 324
Query: 675 VLLKGAHSPIIFH-------VKENSA-GAAIGQIFHTNMSSIYG---------------- 710
+L++ P +FH V E +A G +G + + +
Sbjct: 325 LLVQNVDEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISADAAPPLTRCW 384
Query: 711 --NGTGN-VRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAE------- 759
N G+ R+ I Q ++ I + G I T +PLDRE V+ +TV+A
Sbjct: 385 CPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITVVATERQHFLA 444
Query: 760 -----FNKGVISG----------AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGT 804
F+ V S G V I + D NDNPP Y+ F+ ENS+ G
Sbjct: 445 VHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLA-IDYDTFVCENSEPGQ 503
Query: 805 EIKMDNIIKATDADEGTNALFMYTLFGEGKE--MFDVDENT-GVVKFIGDSLDREKKIMY 861
++ + + + +EG + LF + G+ + D +NT ++ G L R+ ++++
Sbjct: 504 IVQTLSAVDRDEPEEGQHFLFSLSEAGQNLSFTLRDNKDNTASILTRPGGFLQRD-QLLH 562
Query: 862 KLSLVARDTG--GLSSEAELIIMI 883
L +V D+ LSS L I +
Sbjct: 563 LLPVVISDSSRPPLSSTNTLSITV 586
Score = 55.2 bits (127), Expect = 1e-05
Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 5/164 (3%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L +V V L D NDN P F P Y+FS++ + V TV+ K++AVDPD G N + Y
Sbjct: 201 LSGSTSVTVILTDVNDNPPHF-PRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYR 259
Query: 499 LQRTSNLTITS-PFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVV 555
+ L I S + G +++ ++ E + + L VEAS+ + + S
Sbjct: 260 ILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVD-ARFLSSGPFS 318
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
+ R N + P F + V +GT VG + D
Sbjct: 319 DVATVRLLVQNVDEPPVFHSSVSWMMVSEAAAVGTEVGSVLARD 362
Score = 52.4 bits (120), Expect = 9e-05
Identities = 84/344 (24%), Positives = 144/344 (41%), Gaps = 31/344 (9%)
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFV 536
+GK+ + D D G +G V Y L +I F I+ +TG + E + + L
Sbjct: 27 VGKLHS-DVDKG-DGQVRYVLTGEGAASI---FSIDESTGDIHATRRLDREQQAYYTLRA 81
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
+A ++ N S ++ ++ + P F+ PY V +GTSV +
Sbjct: 82 QARNRDTNRLVEPESQFIIKVQDVNDNE------PKFLDGPYTARVAERSPVGTSVVTVV 135
Query: 597 VNDAFEQN-DVSYDLLHGYEEGVP-FAVEERSGVI-TVVDDLSRYNRPMYDFEAVA---L 650
DA + S L++ +G P F+VE ++GV+ T + DL R R + A +
Sbjct: 136 ATDADDPTYGNSARLMYSILQGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMI 195
Query: 651 QENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYG 710
+ LS T+ TV + DVND + ++ F V+E+ + +
Sbjct: 196 GQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQ---FSVRESELVSTVVAKIRAVDPDEGP 252
Query: 711 NGTGNVRFLIANQQ---DVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAE---FNKGV 764
N + R L + +T D + ++G I K LD E + Y + V A +
Sbjct: 253 NAELDYRILDGDGLGIFSITTD-SHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARF 311
Query: 765 ISGAGIYQV-TIYIEDEN-DNPPVFEHATYEGFIMENSKIGTEI 806
+S V T+ + +N D PPVF + + E + +GTE+
Sbjct: 312 LSSGPFSDVATVRLLVQNVDEPPVFHSSVSWMMVSEAAAVGTEV 355
Score = 51.2 bits (117), Expect = 2e-04
Identities = 52/172 (30%), Positives = 77/172 (44%), Gaps = 16/172 (9%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y ++ G + FS++ G + DLD E ++ +L VQA
Sbjct: 139 ADDPTYGNSARLMYSILQG--QPYFSVEPKTGVVRTALP-DLDREVR---DSHLLVVQAK 192
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + + V + L D+NDN P F Y S+ E+ V ++ A D D+G
Sbjct: 193 DMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGP 252
Query: 338 NGEFTYQL--DDPKGAFSIDPRS----GWLTVRNQTVLDREAHSSLRMKVYA 383
N E Y++ D G FSI S G +T+ LD E SS ++V A
Sbjct: 253 NAELDYRILDGDGLGIFSITTDSHTQEGLITLHKN--LDFETKSSYMLRVEA 302
Score = 46.4 bits (105), Expect = 0.006
Identities = 114/498 (22%), Positives = 185/498 (37%), Gaps = 41/498 (8%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIA-----PIGPSLTIPLTVPRGLT 139
+ ++DVNDN P FLD PY V E +P G + G S + ++ +G
Sbjct: 100 IKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSILQGQP 159
Query: 140 IFKDIRAFDRDKPNTPN-----SDVHYSIVSGND-DGHF-ALESSHKPVLLLRKVLDYDA 192
F + P+ D H +V D G L S ++L V D
Sbjct: 160 YFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPP 219
Query: 193 GDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSL--DS-- 248
+ ++ I A+D D G A L Y ++ G+ +FS+ DS
Sbjct: 220 HFPRRSYQFSVRESELVSTVV--AKIRAVDPDEGPNAELDYRILDGDGLGIFSITTDSHT 277
Query: 249 VNGSLFLEKELDLD--AEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G + L K LD + + + L+ L V A L++ + A V + L+ D P F
Sbjct: 278 QEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFSDVATVRL-LVQNVDEPPVF 336
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLD-DPKGAFSIDPRSGWLTVRN 365
+ + E G V V+A D D N D P P S + R
Sbjct: 337 HSSVSWMMVSEAAAVGTEVGSVLARDPD-ATNSPIRISADAAPPLTRCWCPNSLGSSCRY 395
Query: 366 QTVLDREAHSSLRMKVYAKETNPSVVGTF--ADSQRIAKWRRQPLETNAP--LEKTTYVF 421
+DR+++ + + ++ V+ T D + +A + T L + +F
Sbjct: 396 S--IDRQSNLE---RYFHIDSGTGVITTAQPLDRETVAVHNITVVATERQHFLAVHSCLF 450
Query: 422 PDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGK 481
V T + D L V +++ D NDN P Y+ + N++ G ++
Sbjct: 451 SAWV-TSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLAID--YDTFVCENSEPGQIVQT 507
Query: 482 VKAVDPDLGQNGM-VLYDLQRT-SNLTITSPFKINPNTGTVSVAESPILEG---RHALFV 536
+ AVD D + G L+ L NL+ T NT ++ L+ H L V
Sbjct: 508 LSAVDRDEPEEGQHFLFSLSEAGQNLSFTLRDN-KDNTASILTRPGGFLQRDQLLHLLPV 566
Query: 537 EASDQPANPSERRYSLAV 554
SD P +L++
Sbjct: 567 VISDSSRPPLSSTNTLSI 584
Score = 43.2 bits (97), Expect = 0.056
Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 22/161 (13%)
Query: 1259 SRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLV 1318
++++ LE E N P+ + L+ + ++RY + E I F ID G ++
Sbjct: 11 NQFFVLE-EFTGNDPLYVGKLHSDVDKGDGQVRYVLTGEGAASI---FSIDESTGDIHAT 66
Query: 1319 RSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP 1378
R DRE + Y + +A +R+ ++ P ++ +++++DVNDN P
Sbjct: 67 RRLDREQQAYYTLRAQAR----NRDTNRLVEPESQ------------FIIKVQDVNDNEP 110
Query: 1379 KFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
KF +G P + +P G V+ + PT + R
Sbjct: 111 KFLDG--PYTARVAERSPVGTSVVTVVATDADDPTYGNSAR 149
>UniRef50_Q86T00 Cluster: Full-length cDNA clone CS0DK003YO17 of
HeLa cells of Homo sapiens; n=17; Euteleostomi|Rep:
Full-length cDNA clone CS0DK003YO17 of HeLa cells of
Homo sapiens - Homo sapiens (Human)
Length = 370
Score = 84.2 bits (199), Expect = 2e-14
Identities = 67/233 (28%), Positives = 106/233 (45%), Gaps = 9/233 (3%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD-LQRTS 503
V VTL D NDN P F P +LY+FS+ A GT++G+++A DPDLG N ++ Y L
Sbjct: 6 VTVTLSDVNDNPPKF-PQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEG 64
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQPANPSERRYSLAVVTIEVTR 561
+ + + G ++V + E + ++ VEA++ +P+ R + R
Sbjct: 65 SEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG-PFKDVASVR 123
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYEEGVPF 620
+ P+ P F A Y V N GT VGQI D + + Y +L + F
Sbjct: 124 VAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCF 183
Query: 621 AVEERSGVITVVDDLSRYNRPMYDFEAVA--LQENANLSIVTNATVHVVDVND 671
+++ G I L R R ++ +A L +A S V + +D ND
Sbjct: 184 SIQPEEGTIHTAAPLDREARAWHNLTVLATELDSSAQASRV-QVAIQTLDEND 235
Score = 72.1 bits (169), Expect = 1e-10
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 30/283 (10%)
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND--VSYDLLHG 613
T+ VT + P P F + Y+F V G GT VG++R D ++ ++Y +L G
Sbjct: 5 TVTVTLSDVNDNP--PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG 62
Query: 614 YEEGVPFAV----EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDV 669
E F++ + R G++TV L ++ Y F A + + + DV
Sbjct: 63 -EGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFK--DV 119
Query: 670 NDERGVLLKGAHSPII----FH--VKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIAN 722
R + P +H V EN A G +GQI ++ S +R+ I
Sbjct: 120 ASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDS----PASPIRYSILP 175
Query: 723 QQDVTDDIAIA-EDGTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDE 780
D +I E+GTI T PLDRE R + +TV+A E + + A QV I DE
Sbjct: 176 HSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELDSS--AQASRVQVAIQTLDE 233
Query: 781 NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA 823
NDN P Y+ F+ +++ G I+ +I+A D DE N+
Sbjct: 234 NDNAPQLAE-PYDTFVCDSAAPGQLIQ---VIRALDRDEVGNS 272
Score = 56.8 bits (131), Expect = 4e-06
Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 15/182 (8%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFS----LDSVNGSLFLEKELDLDAEHNLQAN--- 270
+ A D DLG A + Y ++ G + FS L +G L + K LD +++ +
Sbjct: 42 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 101
Query: 271 TFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
T L A P K A V + + D + P F Y++++ EN G V Q+ A
Sbjct: 102 TNTLIDPAYLRRGPFKDV-ASVRVAVQDAPEP-PAFTQAAYHLTVPENKAPGTLVGQISA 159
Query: 331 TDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETN 387
D D + Y + DP+ FSI P G T+ LDREA + + V A E +
Sbjct: 160 ADLDSPAS-PIRYSILPHSDPERCFSIQPEEG--TIHTAAPLDREARAWHNLTVLATELD 216
Query: 388 PS 389
S
Sbjct: 217 SS 218
Score = 54.8 bits (126), Expect = 2e-05
Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 292 VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKG- 350
V + L D+NDN P+F Y S+VE G V ++ A D D G+N Y + D +G
Sbjct: 6 VTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGS 65
Query: 351 -AFSIDP----RSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
AFSI R G LTVR LD E+ S +V A T
Sbjct: 66 EAFSISTDLQGRDGLLTVRKP--LDFESQRSYSFRVEATNT 104
Score = 52.4 bits (120), Expect = 9e-05
Identities = 56/220 (25%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEF----NSEVYIPPSKLSA--DALEVKRY 991
F + E GT + +L A D D G N + Y SE + + L L V++
Sbjct: 27 FSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 86
Query: 992 FVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
+ + + + ++ + L G D SVRV V+D + P F + Y+
Sbjct: 87 LDFESQRSYSFRVEA----TNTLIDPAYLRRGPFKDVASVRVAVQDAPEP-PAFTQAAYH 141
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP-SDTDLPFEISPLTGVLSVNGELDR 1110
V E + ++G++ A D D + + Y I P SD + F I P G + LDR
Sbjct: 142 LTVPENKAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDR 200
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
E + LTV+A + D NDN+P+
Sbjct: 201 EARAWHNLTVLATEL-DSSAQASRVQVAIQTLDENDNAPQ 239
Score = 52.0 bits (119), Expect = 1e-04
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 768 AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMY 827
+G VT+ + D NDNPP F + Y+ ++E + GT + ++A D D G NAL Y
Sbjct: 1 SGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV---GRLRAQDPDLGDNALMAY 57
Query: 828 TLF-GEGKEMF----DVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
++ GEG E F D+ G++ + LD E + Y + A +T
Sbjct: 58 SILDGEGSEAFSISTDLQGRDGLLT-VRKPLDFESQRSYSFRVEATNT 104
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDT 1089
+V V + DVND+ P F ++ Y F+V E ++G++ A D D G NA + Y I +
Sbjct: 5 TVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEG 64
Query: 1090 DLPFEISP----LTGVLSVNGELDRETEDKYILTVVA 1122
F IS G+L+V LD E++ Y V A
Sbjct: 65 SEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 101
Score = 48.8 bits (111), Expect = 0.001
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 735 DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA--------GIYQVTIYIEDENDNPPV 786
DG + +KPLD E + Y V E +I A + V + ++D + PP
Sbjct: 78 DGLLTVRKPLDFESQRSYSFRV--EATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPA 134
Query: 787 FEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-FGEGKEMFDVDENTGV 845
F A Y + EN GT + I A D D + + L + + F + G
Sbjct: 135 FTQAAYHLTVPENKAPGTLVGQ---ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGT 191
Query: 846 VKFIGDSLDREKKIMYKLSLVAR--DTGGLSSEAELIIMIGDENDNKPE 892
+ LDRE + + L+++A D+ +S ++ I DENDN P+
Sbjct: 192 IHTAAP-LDREARAWHNLTVLATELDSSAQASRVQVAIQTLDENDNAPQ 239
>UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n=5;
Diptera|Rep: Putative neural-cadherin 2 precursor -
Drosophila melanogaster (Fruit fly)
Length = 2215
Score = 83.8 bits (198), Expect = 3e-14
Identities = 51/164 (31%), Positives = 82/164 (50%), Gaps = 10/164 (6%)
Query: 743 PLDREK---RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
PLDR++ R +R TV A+ ++G G + + ++D NDN P F Y G + EN
Sbjct: 376 PLDRDQPNGRPQWRFTVFAQ-DEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTEN 434
Query: 800 SKIGTEIKMDNIIKATDADEGTNALFMYTLFGE------GKEMFDVDENTGVVKFIGDSL 853
G+ + + + D +E TNA +Y++ G +F+++ TG++K L
Sbjct: 435 GTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCL 494
Query: 854 DREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIE 897
DRE+ Y + +VA D GGL I + D ND P+F + E
Sbjct: 495 DRERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTKDE 538
Score = 66.5 bits (155), Expect = 5e-09
Identities = 147/614 (23%), Positives = 243/614 (39%), Gaps = 71/614 (11%)
Query: 819 EGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAE 878
E TN + T G F V TGV+ ++ LD E + Y+L L A ++
Sbjct: 178 ESTNIRYQIT-GGNIGNAFAVQNTTGVI-YVASPLDYETRPRYELRLEAT-RNRKNNYTT 234
Query: 879 LIIMIGDENDNKPEFN------QIEE----NSKVRIHRETKLNGTAGFTIIEVKPKNKFA 928
++I + D NDN P F+ QI E N RI + T +G I V
Sbjct: 235 VVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQG 294
Query: 929 LDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSE----VYIP-PSKLSA 983
+D D ++K L + + N ++I + +S+
Sbjct: 295 IDPDNPANSKFDINRTTGDIFVLKAKTKRLTGPKHSHTQATHNKRMLKGIFIEWMAFISS 354
Query: 984 DALEVKRYFVINERHGHVIVA---RSLPP-ESEFRLNISALDGGN--LNDNISVRVFVKD 1037
A++ + NE+ + ++ R P ++R + A D G L ++V +KD
Sbjct: 355 LAMQFRVDNSFNEKSNNRLLCPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKD 414
Query: 1038 VNDHFPVFKKTWYNFNVEE---AQYTRRVLGKVDATDADFGQNANLTYFIQPS----DTD 1090
+ND+ P F + Y NV E A + + VD D + NA L Y I+ + +T
Sbjct: 415 INDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETG 474
Query: 1091 LP-FEISPLTGVL-SVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNS 1148
P FEI P TG++ + LDRE Y + VVA D G D+ND
Sbjct: 475 APIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGG---GLKGTGTASIRVKDLNDMP 531
Query: 1149 PKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAND---TD 1205
P+F EW E+ N + P+ T+++ T KV N D
Sbjct: 532 PQFTKD----EW----VTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGAD 583
Query: 1206 ---FIGNGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDE-VEMSDKPVFISRY 1261
+ NG+G + Q + ++ P SS + V D D+ SDK +
Sbjct: 584 KFAMVRNGDGTGSLKIIQPLDYED---PLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSW 640
Query: 1262 YELEIEE-NVNAPV---ELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLY- 1316
+++ + N N P E + +++ YE+ K+ + TD + + Y
Sbjct: 641 VVVKLRDINDNVPKFDREHIEVSI---YEDTKVGTILEQFKATDADQ----GGHSKVAYK 693
Query: 1317 LVRSPDRE----VKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVRIKD 1372
+VRS +R+ + D V ++ + +++ H+ +D T V+ +KD
Sbjct: 694 IVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVI-VKD 752
Query: 1373 VNDNSPKFTNGNRP 1386
VNDN+P F +P
Sbjct: 753 VNDNAPTFAQDYKP 766
Score = 66.5 bits (155), Expect = 5e-09
Identities = 80/301 (26%), Positives = 134/301 (44%), Gaps = 30/301 (9%)
Query: 615 EEGVP-FAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
E G P F +E +G+I T V L R P Y + VA+ + L A++ V D+ND
Sbjct: 472 ETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAM-DGGGLKGTGTASIRVKDLNDM 530
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF-LIANQQDVTDDIA 731
K + V E + G I + ++ + T ++ ++ N D A
Sbjct: 531 PPQFTKDEW---VTEVDETN-GTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFA 586
Query: 732 IAEDG----TIFTQKPLDRE---KRDVYRMTV-IAEFNKGVISGAGIYQVT-----IYIE 778
+ +G ++ +PLD E + +R + + + G+ Y V + +
Sbjct: 587 MVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLR 646
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF--GEGKEM 836
D NDN P F+ E I E++K+GT ++ KATDAD+G ++ Y + K
Sbjct: 647 DINDNVPKFDREHIEVSIYEDTKVGTILEQ---FKATDADQGGHSKVAYKIVRSTNRKRQ 703
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFN 894
F + + G V I LDRE + + + ++A D G ++ A L +++ D NDN P F
Sbjct: 704 FAISDR-GAVS-IQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFA 761
Query: 895 Q 895
Q
Sbjct: 762 Q 762
Score = 66.5 bits (155), Expect = 5e-09
Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 22/193 (11%)
Query: 216 EPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
E A D D G + + Y+++ +RK S G++ +++ LD + + +Q
Sbjct: 675 EQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHH-----IQ 729
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD- 334
+ A +P +TA A + + + D+NDN P F D Y ++ EN+ +G +L+V A D D
Sbjct: 730 ILAIDDGSPARTATATLTVIVKDVNDNAPTFAQD-YKPTLPENV-SGKKILEVAAKDPDD 787
Query: 335 --QGENGEFTYQL-----DDPKGAFSI------DPRSGWLTVRNQTVLDREAHSSLRMKV 381
+G G FT++L D+ K F + D +G + + DREA S + +
Sbjct: 788 RLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPI 847
Query: 382 YAKETN-PSVVGT 393
K+ P++ GT
Sbjct: 848 EIKDNGAPAMTGT 860
Score = 64.5 bits (150), Expect = 2e-08
Identities = 130/542 (23%), Positives = 219/542 (40%), Gaps = 87/542 (16%)
Query: 640 RPMYDFEAVALQENAN-LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAI 697
RP + F A E L + V++ D+ND +G + +V EN +AG+++
Sbjct: 385 RPQWRFTVFAQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIY---FGNVTENGTAGSSV 441
Query: 698 GQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA-------EDGTIFTQKP-LDREKR 749
+ + N + N + + + +++V ++ A E G I T LDRE+
Sbjct: 442 MTMSAVDYDD--PNESTNAKLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERT 499
Query: 750 DVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
Y + V+A + G + G G +I ++D ND PP F + + E + GT I
Sbjct: 500 PDYSIQVVA-MDGGGLKGTGT--ASIRVKDLNDMPPQFTKDEWVTEVDETN--GTYIPET 554
Query: 810 NIIKATDADEGTNALFMYTLF---GEGKEMFDVDEN---TGVVKFIGDSLDREKKIMYKL 863
I+ T DE F Y + G G + F + N TG +K I LD E +
Sbjct: 555 PILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGTGSLKII-QPLDYEDPLQ--- 610
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKP 923
SS I + D+ D+ P + K + + +++++
Sbjct: 611 ----------SSGFRFRIQVNDKGDDGPGGSD-------------KYHVAYSWVVVKLRD 647
Query: 924 KNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSA 983
N D+ I E+ +GT + + A D D G + ++ Y+
Sbjct: 648 INDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKI------------V 695
Query: 984 DALEVKRYFVINERHGHVIVARSLPPESEFR--LNISALDGGN--LNDNISVRVFVKDVN 1039
+ KR F I++R G V + R L E++ R + I A+D G+ ++ V VKDVN
Sbjct: 696 RSTNRKRQFAISDR-GAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVN 754
Query: 1040 DHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTD---LPF 1093
D+ P F + Y + E +++L +V A D D G T+ + P +D F
Sbjct: 755 DNAPTFAQD-YKPTLPENVSGKKIL-EVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGF 812
Query: 1094 EI------SPLTGVLSVNG--ELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVN 1145
++ GV ++ DRE + Y + + +DNG DVN
Sbjct: 813 KVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNG-APAMTGTSTLTVTIGDVN 871
Query: 1146 DN 1147
DN
Sbjct: 872 DN 873
Score = 59.7 bits (138), Expect = 6e-07
Identities = 76/311 (24%), Positives = 140/311 (45%), Gaps = 26/311 (8%)
Query: 406 QPLETNAPLEKTTYVFPDKVGTKTENIEY-YDEQLMSFVNVEVTLLDANDNNPVFVPSNL 464
QPL+ PL+ + + F +V K ++ D+ +++ V V L D NDN P F ++
Sbjct: 601 QPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHI 660
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAE 524
E S+ + KVGT++ + KA D D G + V Y + R++N F I+ + G VS+ +
Sbjct: 661 -EVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNR--KRQFAIS-DRGAVSI-Q 715
Query: 525 SPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDI-PDFMGAPYEF 580
P+ + RH + + A D + S R + A +T+ + + N P D+ E
Sbjct: 716 RPLDRETQDRHHIQILAID---DGSPARTATATLTV-IVKDVNDNAPTFAQDYKPTLPEN 771
Query: 581 WVGSNV-GIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVE-ERSG----VITVVDD 634
G + + R+ D L E F VE +R G + ++
Sbjct: 772 VSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISS 831
Query: 635 LSRYNRPMYDFEAVALQENAN----LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKE 690
L ++R A+ ++ N ++ + TV + DVND + + G+ S ++++ +
Sbjct: 832 LRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNK--MQPGSKSVLVYNYQG 889
Query: 691 NSAGAAIGQIF 701
S IG+++
Sbjct: 890 QSQDTPIGRVY 900
Score = 57.2 bits (132), Expect = 3e-06
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 16/192 (8%)
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
G V + I + AI++ G + Q+PLDRE +D + + ++A + G +
Sbjct: 686 GHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQILA-IDDGSPARTATA 744
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL-- 829
+T+ ++D NDN P F Y+ + EN G +I D G F + L
Sbjct: 745 TLTVIVKDVNDNAPTFAQ-DYKPTLPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDP 802
Query: 830 --FGEGKEMFDVD-----ENTGVVKFIGD--SLDREKKIMYKLSLVARDTG--GLSSEAE 878
E K F V+ +N V I DRE + Y + + +D G ++ +
Sbjct: 803 LASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTST 862
Query: 879 LIIMIGDENDNK 890
L + IGD NDNK
Sbjct: 863 LTVTIGDVNDNK 874
Score = 52.4 bits (120), Expect = 9e-05
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 13/133 (9%)
Query: 261 LDAEHNLQANTFVLQVQASQL-------NNPLKTAQARVEIELLDLNDNLPEFEVDFYNI 313
LD E LQ++ F ++Q + ++ A + V ++L D+NDN+P+F+ + +
Sbjct: 603 LDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEV 662
Query: 314 SIVENLPNGFSVLQVMATDKDQGENGEFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLD 370
SI E+ G + Q ATD DQG + + Y++ + K F+I R V Q LD
Sbjct: 663 SIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRG---AVSIQRPLD 719
Query: 371 REAHSSLRMKVYA 383
RE +++ A
Sbjct: 720 RETQDRHHIQILA 732
Score = 48.4 bits (110), Expect = 0.002
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 715 NVRFLIANQQDVTDDIAIAED-GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQV 773
N+R+ I ++ + A+ G I+ PLD E R Y + + A N+ V
Sbjct: 181 NIRYQITGG-NIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRK----NNYTTV 235
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEG 833
I + D NDNPPVF+ TY I E ++ + ATD D +Y L G+G
Sbjct: 236 VINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQ-VTATDGDVDRPINIVYFLTGQG 294
Query: 834 -------KEMFDVDENTG 844
FD++ TG
Sbjct: 295 IDPDNPANSKFDINRTTG 312
Score = 46.4 bits (105), Expect = 0.006
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 437 EQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAV---DPDLGQNG 493
E L+ + +++V L D NDN P F P +Y ++ N G+ + + AV DP+ N
Sbjct: 400 EGLVGYADIQVNLKDINDNAPQF-PQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNA 458
Query: 494 MVLYDLQRT--SNLTITSPFKINPNTGTVSVA 523
++Y +++ T F+I P TG + A
Sbjct: 459 KLIYSIEKNVIEEETGAPIFEIEPETGLIKTA 490
Score = 44.4 bits (100), Expect = 0.024
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 14/117 (11%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
DQ +RY++ GN F++ + G +++ LD + + L+ ++
Sbjct: 173 DQLQRESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELR---LEATRNRK 229
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVE----NLPNGFSVLQVMATDKD 334
NN V I + D+NDN P F+ Y I E NLP +LQV ATD D
Sbjct: 230 NN-----YTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPK--RILQVTATDGD 279
Score = 44.0 bits (99), Expect = 0.032
Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD---QGENGEFTYQ-- 344
A +++ L D+NDN P+F Y ++ EN G SV+ + A D D + N + Y
Sbjct: 406 ADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIE 465
Query: 345 ---LDDPKGA--FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQR 399
+++ GA F I+P +G L LDRE ++V A + + GT S R
Sbjct: 466 KNVIEEETGAPIFEIEPETG-LIKTAVCCLDRERTPDYSIQVVAMD-GGGLKGTGTASIR 523
Query: 400 IAKWRRQP 407
+ P
Sbjct: 524 VKDLNDMP 531
Score = 43.6 bits (98), Expect = 0.043
Identities = 80/351 (22%), Positives = 138/351 (39%), Gaps = 30/351 (8%)
Query: 54 KFRLGCDFDEGDDLVRIGAGLNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+FR+ + D+GDD G AY V V + D+NDNVP F V++ E T G
Sbjct: 615 RFRIQVN-DKGDD--GPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVG 671
Query: 114 E--KAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDR-----DKP-NTPNSDVHYSIVS 165
+ F A G + + R + DR +P + D H+ +
Sbjct: 672 TILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQIL 731
Query: 166 GNDDGHFALESSHKPVLLLRKVLDYD---AGDKEFQLVIMASGKRIHKEILFPEPIHAID 222
DDG A ++ ++++ V D A D + L SGK+I E+ +P +
Sbjct: 732 AIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPTLPENVSGKKI-LEVAAKDPDDRL- 789
Query: 223 QDLGVGATLRYELISGNDRKL-FSL------DSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ G T R + ++ ++ K F + D+ NG + D E ++ +
Sbjct: 790 RGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDRE---AQKSYAIP 846
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ 335
++ P T + + + + D+NDN + + + + +V D D
Sbjct: 847 IEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQDTPIGRVYVNDPDD 906
Query: 336 GENGEFTYQLD-DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ + Y + F +D +G LT+R T R LR KVY +E
Sbjct: 907 WDVPDKKYYWEVQEHQRFKLDTDTGILTMRAGT---RRGRYQLRFKVYDRE 954
Score = 36.3 bits (80), Expect = 6.5
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 602 EQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTN 661
E ++ Y + G G FAV+ +GVI V L RP Y+ A + N T
Sbjct: 178 ESTNIRYQITGG-NIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKN--NYTT 234
Query: 662 ATVHVVDVND 671
++V DVND
Sbjct: 235 VVINVRDVND 244
>UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19;
Euteleostomi|Rep: Cadherin-22 precursor - Homo sapiens
(Human)
Length = 828
Score = 83.8 bits (198), Expect = 3e-14
Identities = 76/254 (29%), Positives = 113/254 (44%), Gaps = 16/254 (6%)
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
VG+I +D+ E + + G G F ++E +G I ++ L R + Y A A
Sbjct: 83 VGKIH-SDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARD 141
Query: 652 ENAN--LSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSS- 707
N L + + V D+ND L H P I V E S G ++ Q+ ++
Sbjct: 142 RATNRLLEPESEFIIKVQDINDSEPRFL---HGPYIGSVAELSPTGTSVMQVMASDADDP 198
Query: 708 IYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVIS 766
YG+ V ++ + T D + G I T P LDRE ++ Y + + A G +
Sbjct: 199 TYGSSARLVYSVLDGEHHFTVD---PKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLG 255
Query: 767 G-AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
G +G VTI + D NDNPP F Y+ I E++ IGT + +KA D+D G N
Sbjct: 256 GLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAV---GRVKAEDSDVGENTDM 312
Query: 826 MYTLFGEGKEMFDV 839
Y L E DV
Sbjct: 313 TYHLKDESSSGGDV 326
Score = 83.4 bits (197), Expect = 4e-14
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 5/188 (2%)
Query: 712 GTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIY 771
G G +++ I+ + T + G I + LDRE++ Y + A
Sbjct: 93 GDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPES 152
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
+ I ++D ND+ P F H Y G + E S GT + A D G++A +Y++
Sbjct: 153 EFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVL- 211
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDEN 887
+G+ F VD TGV++ LDRE + Y++ + A D GGLS + I++ D N
Sbjct: 212 DGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVN 271
Query: 888 DNKPEFNQ 895
DN P F Q
Sbjct: 272 DNPPRFPQ 279
Score = 79.4 bits (187), Expect = 7e-13
Identities = 117/466 (25%), Positives = 199/466 (42%), Gaps = 51/466 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D ND+ P F+ Y S+ + GT + +V A D P G + ++Y +
Sbjct: 156 IKVQDINDSEPRFLHGP-YIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSV---- 210
Query: 504 NLTITSPFKINPNTGTVSVAESPI---LEGRHALFVEASDQPANPSERRYSLAVVTIEVT 560
L F ++P TG + A + + R+ + ++A+D S VTI VT
Sbjct: 211 -LDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGS-TTVTIVVT 268
Query: 561 RGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEG- 617
N P P M Y+F + + IGT+VG+++ D+ E D++Y L G
Sbjct: 269 -DVNDNPPRFPQKM---YQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGG 324
Query: 618 ----VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-----ANLSIVTNATVHVVD 668
V + + +I V L ++P++ AL + A+L + + V
Sbjct: 325 DVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVA 384
Query: 669 VNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD 728
V D S ++ ++ G+ +G + + + VR+ I + D+
Sbjct: 385 VTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDA----ANRPVRYAIDRESDLDQ 440
Query: 729 DIAI-AEDGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDENDNPP 785
I A+ G I T K LDRE + +TV+A N +S A + I I D NDNPP
Sbjct: 441 IFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASL---RIRILDVNDNPP 497
Query: 786 VFEHAT-YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK-----EMFDV 839
E AT YE + E++K G I+ +++ + G F + L E + D+
Sbjct: 498 --ELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHR--FYFRLVPEAPSNPHFSLLDI 553
Query: 840 DENTGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMI 883
+NT V +R+++ ++ L ++ D+G LSS L I I
Sbjct: 554 QDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRI 599
Score = 78.2 bits (184), Expect = 2e-12
Identities = 117/441 (26%), Positives = 197/441 (44%), Gaps = 52/441 (11%)
Query: 479 IGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGR--HALFV 536
+GK+ + D D G +G + Y + TI F I+ TG + E E + + L
Sbjct: 83 VGKIHS-DSDEG-DGAIKYTISGEGAGTI---FLIDELTGDIHAMERLDREQKTFYTLRA 137
Query: 537 EASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIR 596
+A D+ N S ++ ++ ++ P F+ PY V GTSV Q+
Sbjct: 138 QARDRATNRLLEPESEFIIKVQDINDSE------PRFLHGPYIGSVAELSPTGTSVMQVM 191
Query: 597 VNDAFEQN-DVSYDLLHGYEEGV-PFAVEERSGVI-TVVDDLSRYNRPMYDFEAVALQ-- 651
+DA + S L++ +G F V+ ++GVI T V DL R ++ Y+ A
Sbjct: 192 ASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMA 251
Query: 652 -ENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENS-AGAAIGQIFHTNMSSIY 709
+ LS T T+ V DVND + + F ++E++ G A+G++ S
Sbjct: 252 GQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQ---FSIQESAPIGTAVGRV--KAEDSDV 306
Query: 710 GNGTGNVRFLIANQQDVTDDI------AIAEDGTIFTQKPLDREKRDVYRMTVIAE-FNK 762
G T ++ + + ++ D+ + ++ I QK LD E + V+ TVI E NK
Sbjct: 307 GENT-DMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVH--TVILEALNK 363
Query: 763 GV---ISGAGIYQ----VTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKAT 815
V + G ++ V + + D D PP F + + E++++G+ + ++ A
Sbjct: 364 FVDPRFADLGTFRDQAIVRVAVTDV-DEPPEFRPPSGLLEVQEDAQVGSLV---GVVTAR 419
Query: 816 DADEGTNALFMYTLFGEG--KEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVA--RDTG 871
D D N Y + E ++FD+D +TG + G LDRE + ++++A D
Sbjct: 420 DPD-AANRPVRYAIDRESDLDQIFDIDADTGAI-VTGKGLDRETAGWHNITVLAMEADNH 477
Query: 872 GLSSEAELIIMIGDENDNKPE 892
S A L I I D NDN PE
Sbjct: 478 AQLSRASLRIRILDVNDNPPE 498
Score = 68.1 bits (159), Expect = 2e-09
Identities = 52/179 (29%), Positives = 87/179 (48%), Gaps = 12/179 (6%)
Query: 211 EILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
E L+ IH+ D D G GA ++Y + +F +D + G + + LD + Q
Sbjct: 79 EPLYVGKIHS-DSDEGDGA-IKYTISGEGAGTIFLIDELTGDIHAMERLDRE-----QKT 131
Query: 271 TFVLQVQA-SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ L+ QA + N L ++ I++ D+ND+ P F Y S+ E P G SV+QVM
Sbjct: 132 FYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVM 191
Query: 330 ATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A+D D G + Y + D + F++DP++G + LDRE+ + + A +
Sbjct: 192 ASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPD-LDRESQERYEVVIQATD 249
Score = 66.5 bits (155), Expect = 5e-09
Identities = 58/242 (23%), Positives = 111/242 (45%), Gaps = 13/242 (5%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V + + D NDN P F P +Y+FS++ +A +GT +G+VKA D D+G+N + Y
Sbjct: 257 LSGSTTVTIVVTDVNDNPPRF-PQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYH 315
Query: 499 LQRTSNLTITSPFKINPNTGT----VSVAESPILEGR--HALFVEASDQPANPSERRYSL 552
L+ S+ + FK+ ++ T + V + E + H + +EA ++ +P R L
Sbjct: 316 LKDESS-SGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDP--RFADL 372
Query: 553 AVVTIE-VTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDL 610
+ + R + + P+F V + +G+ VG + D N V Y +
Sbjct: 373 GTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAI 432
Query: 611 LHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV-TNATVHVVDV 669
+ F ++ +G I L R ++ +A++ + + + + + ++DV
Sbjct: 433 DRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDV 492
Query: 670 ND 671
ND
Sbjct: 493 ND 494
Score = 62.9 bits (146), Expect = 7e-08
Identities = 64/222 (28%), Positives = 92/222 (41%), Gaps = 16/222 (7%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPS--KLSADALEVKRYFVIN 995
F I E+ PIGT + ++ A D D G N + Y E K++ D+ + V+
Sbjct: 284 FSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQ 343
Query: 996 ERHG------HVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTW 1049
+R H ++ +L + R D G D VRV V DV D P F+
Sbjct: 344 KRLDFESQPVHTVILEALNKFVDPRF----ADLGTFRDQAIVRVAVTDV-DEPPEFRPPS 398
Query: 1050 YNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI-QPSDTDLPFEISPLTGVLSVNGEL 1108
V+E ++G V A D D N + Y I + SD D F+I TG + L
Sbjct: 399 GLLEVQEDAQVGSLVGVVTARDPD-AANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGL 457
Query: 1109 DRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
DRET + +TV+A + DVNDN P+
Sbjct: 458 DRETAGWHNITVLAME-ADNHAQLSRASLRIRILDVNDNPPE 498
Score = 61.3 bits (142), Expect = 2e-07
Identities = 64/224 (28%), Positives = 99/224 (44%), Gaps = 38/224 (16%)
Query: 992 FVINERHGHVIVARSLPPESE--FRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
F+I+E G + L E + + L A D L + V+D+ND P F
Sbjct: 110 FLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFL 169
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVL- 1102
Y +V E T + +V A+DAD +G +A L Y + D + F + P TGV+
Sbjct: 170 HGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVL--DGEHHFTVDPKTGVIR 227
Query: 1103 SVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWK 1161
+ +LDRE++++Y + + A D G DVNDN P+F
Sbjct: 228 TAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRF---------- 277
Query: 1162 HPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTD 1205
P+ +Y+ +I+E+APIGT V +V A D+D
Sbjct: 278 -PQ---------------KMYQFSIQESAPIGTAVGRVKAEDSD 305
Score = 58.0 bits (134), Expect = 2e-06
Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 8/130 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y ++ G F++D G + DLD E + + +QA+
Sbjct: 195 ADDPTYGSSARLVYSVLDGEHH--FTVDPKTGVIRTAVP-DLDRESQ---ERYEVVIQAT 248
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ L + V I + D+NDN P F Y SI E+ P G +V +V A D D GE
Sbjct: 249 DMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGE 308
Query: 338 NGEFTYQLDD 347
N + TY L D
Sbjct: 309 NTDMTYHLKD 318
Score = 57.2 bits (132), Expect = 3e-06
Identities = 48/182 (26%), Positives = 90/182 (49%), Gaps = 29/182 (15%)
Query: 921 VKPKNKFAL---DVDQLGPLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
++P+++F + D++ P FL + E P GT+++++ A D D G
Sbjct: 148 LEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGS----- 202
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVA-RSLPPESEFRLN--ISALDG----G 1023
++L L+ + +F ++ + G + A L ES+ R I A D G
Sbjct: 203 -------SARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLG 255
Query: 1024 NLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYF 1083
L+ + +V + V DVND+ P F + Y F+++E+ +G+V A D+D G+N ++TY
Sbjct: 256 GLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYH 315
Query: 1084 IQ 1085
++
Sbjct: 316 LK 317
Score = 50.0 bits (114), Expect = 5e-04
Identities = 66/293 (22%), Positives = 116/293 (39%), Gaps = 34/293 (11%)
Query: 74 LNQISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLT 133
L +S +VT+ + DVNDN P F Y ++ E P G +T
Sbjct: 254 LGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMT 313
Query: 134 VPRGLTIFKDIRAFDRDKPN-TPNSDVHYSIVSGNDDGHFALESSHKPVL-LLRKVLD-- 189
KD + D T +SD +I+ F + H +L L K +D
Sbjct: 314 YH-----LKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPR 368
Query: 190 -YDAGDKEFQLVIMASGKRIHKEILF--PEPIHAIDQDLGVGATL--------------- 231
D G Q ++ + + + F P + + +D VG+ +
Sbjct: 369 FADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPV 428
Query: 232 RYELISGNDR-KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
RY + +D ++F +D+ G++ K LD + A + V A + +N + ++A
Sbjct: 429 RYAIDRESDLDQIFDIDADTGAIVTGKGLDRET-----AGWHNITVLAMEADNHAQLSRA 483
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTY 343
+ I +LD+NDN PE Y ++ E+ G + + D+D+ + G Y
Sbjct: 484 SLRIRILDVNDNPPELATP-YEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFY 535
Score = 45.2 bits (102), Expect = 0.014
Identities = 74/304 (24%), Positives = 120/304 (39%), Gaps = 33/304 (10%)
Query: 1052 FNVEEAQYTRRV-LGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
F VEE T + +GK+ + D+D G A + Y I F I LTG + LDR
Sbjct: 70 FVVEEYTGTEPLYVGKIHS-DSDEGDGA-IKYTISGEGAGTIFLIDELTGDIHAMERLDR 127
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSN 1170
E + Y L ARD D+ND+ P+F + ELS
Sbjct: 128 EQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI-----GSVAELSP 182
Query: 1171 HNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDF-IGNGNGLILYSLP--QRKNQQNL 1227
SVM + A V V + F + G+I ++P R++Q+
Sbjct: 183 TG-TSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERY 241
Query: 1228 -----------GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEEN--VNAPV 1274
L LS + + + V DV D + P F + Y+ I+E+ + V
Sbjct: 242 EVVIQATDMAGQLGGLSGSTTVTIVVTDVND-----NPPRFPQKMYQFSIQESAPIGTAV 296
Query: 1275 ELVSLNLTEHYENFKMRYYILNENDT--DI-RRTFVIDPRNGTLYLVRSPDREVKDTYEV 1331
V ++ EN M Y++ +E+ + D+ + T D + + + + D E + + V
Sbjct: 297 GRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTV 356
Query: 1332 IVRA 1335
I+ A
Sbjct: 357 ILEA 360
Score = 41.5 bits (93), Expect = 0.17
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 18/114 (15%)
Query: 1306 FVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVK 1365
F+ID G ++ + DRE K Y + +A + +R ++ P +E
Sbjct: 110 FLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNR----LLEPESE------------ 153
Query: 1366 VVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
+++++D+ND+ P+F +G P + ++ +P G VMQ+ + PT + R
Sbjct: 154 FIIKVQDINDSEPRFLHG--PYIGSVAELSPTGTSVMQVMASDADDPTYGSSAR 205
>UniRef50_UPI000155D1D0 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 447
Score = 83.4 bits (197), Expect = 4e-14
Identities = 56/161 (34%), Positives = 83/161 (51%), Gaps = 14/161 (8%)
Query: 738 IFTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFI 796
+ + PLDRE+RD Y +T+ + + + S + +V I D NDN P FE A YE +
Sbjct: 252 LIVKGPLDRERRDAYELTLRVRDGGRPARSSQALLRVLI--TDVNDNSPRFERAVYEAEL 309
Query: 797 MENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKE----MFDVDENTGVVKFIGDS 852
ENS GT I ++A+D D G N Y +FG E + +DE TG + +
Sbjct: 310 AENSSPGTPILQ---LRASDLDAGVNGQIEY-VFGAATEAVRRLLRLDEATGWLSVL-HR 364
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKP 891
+DRE+ + + ARD G S A +++ + DENDN P
Sbjct: 365 IDREEVSQLRFGVTARDRGQPARSDRATVLLAVRDENDNVP 405
Score = 66.5 bits (155), Expect = 5e-09
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 6/120 (5%)
Query: 270 NTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+ + L ++ P +++QA + + + D+NDN P FE Y + EN G +LQ+
Sbjct: 264 DAYELTLRVRDGGRPARSSQALLRVLITDVNDNSPRFERAVYEAELAENSSPGTPILQLR 323
Query: 330 ATDKDQGENGEFTY----QLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
A+D D G NG+ Y + + +D +GWL+V ++ +DRE S LR V A++
Sbjct: 324 ASDLDAGVNGQIEYVFGAATEAVRRLLRLDEATGWLSVLHR--IDREEVSQLRFGVTARD 381
Score = 50.0 bits (114), Expect = 5e-04
Identities = 38/141 (26%), Positives = 57/141 (40%), Gaps = 5/141 (3%)
Query: 1013 FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDAT 1070
+ L + DGG + +RV + DVND+ P F++ Y + E + ++ A+
Sbjct: 266 YELTLRVRDGGRPARSSQALLRVLITDVNDNSPRFERAVYEAELAENSSPGTPILQLRAS 325
Query: 1071 DADFGQNANLTYFIQPSDTDLP--FEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
D D G N + Y + + + TG LSV +DRE + V ARD G
Sbjct: 326 DLDAGVNGQIEYVFGAATEAVRRLLRLDEATGWLSVLHRIDREEVSQLRFGVTARDRG-Q 384
Query: 1129 XXXXXXXXXXXXXXDVNDNSP 1149
D NDN P
Sbjct: 385 PARSDRATVLLAVRDENDNVP 405
Score = 48.4 bits (110), Expect = 0.002
Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 15/108 (13%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHG 999
+ EN GT I++L A DLD+G+NGQI Y F + + +A V+R ++E G
Sbjct: 309 LAENSSPGTPILQLRASDLDAGVNGQIEYVFGA---------ATEA--VRRLLRLDEATG 357
Query: 1000 HVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFP 1043
+ V + E S+ R ++A D G +D +V + V+D ND+ P
Sbjct: 358 WLSVLHRIDREEVSQLRFGVTARDRGQPARSDRATVLLAVRDENDNVP 405
Score = 44.4 bits (100), Expect = 0.024
Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 294 IELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQ-LDDPKG 350
+ +LD+NDN P F +++ EN P G L ATD+D G NG Y+ L +P G
Sbjct: 125 VVVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGG 182
Score = 43.6 bits (98), Expect = 0.043
Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
V +LD NDN P F PS + +++ N VGT+ A D D G+NG+ Y+L
Sbjct: 125 VVVLDINDNTPTF-PSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 176
Score = 41.1 bits (92), Expect = 0.23
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ V + D NDN+P F + +YE + N+ GT I +++A D D G NG + Y +
Sbjct: 286 LRVLITDVNDNSPRFERA-VYEAELAENSSPGTPILQLRASDLDAGVNGQIEYVFGAATE 344
Query: 505 LTITSPFKINPNTGTVSVA----ESPILEGRHALFVEASDQPANPSERRYSLAV 554
+ +++ TG +SV + + R + QPA LAV
Sbjct: 345 -AVRRLLRLDEATGWLSVLHRIDREEVSQLRFGVTARDRGQPARSDRATVLLAV 397
Score = 39.9 bits (89), Expect = 0.53
Identities = 21/45 (46%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
Query: 853 LDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQ 895
LDRE++ Y+L+L RD G SS+A L ++I D NDN P F +
Sbjct: 258 LDRERRDAYELTLRVRDGGRPARSSQALLRVLITDVNDNSPRFER 302
Score = 39.5 bits (88), Expect = 0.69
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 1102 LSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
L V G LDRE D Y LT+ RD G DVNDNSP+F
Sbjct: 252 LIVKGPLDRERRDAYELTLRVRDGG-RPARSSQALLRVLITDVNDNSPRF 300
Score = 36.7 bits (81), Expect = 4.9
Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 218 IHAIDQDLGVGATLRYELISGND--RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A D D GV + Y + + R+L LD G L + +D + L+
Sbjct: 322 LRASDLDAGVNGQIEYVFGAATEAVRRLLRLDEATGWLSVLHRIDREEVSQLRFG----- 376
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYN-------ISIV-ENLPNGFSVLQ 327
V A P ++ +A V + + D NDN+P ++ +++V E+ V
Sbjct: 377 VTARDRGQPARSDRATVLLAVRDENDNVPAIDIRKIGRIPLRDGVALVGEDALVDTPVAL 436
Query: 328 VMATDKDQGEN 338
V +D+DQGEN
Sbjct: 437 VQVSDRDQGEN 447
>UniRef50_Q4SM63 Cluster: Chromosome 13 SCAF14555, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF14555, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 590
Score = 83.0 bits (196), Expect = 6e-14
Identities = 115/421 (27%), Positives = 184/421 (43%), Gaps = 41/421 (9%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA-Q 289
+ Y L+ N LFS+ G + L + LD +++ ++L V+AS+ L A +
Sbjct: 180 ISYSLLI-NPSSLFSIRPETGEISLTRTLDYESDQR----RYLLMVRASEEPGILSAAAE 234
Query: 290 ARVEIELLDLNDNLPEFEVDFYNIS-IVENLPNGFSVLQVMATDKDQGENGEFTYQLDDP 348
RV++ + D ND +PEF Y++ + E + S+LQV+ATD D G N E TY + P
Sbjct: 235 VRVQVLITDENDCVPEFLQSIYSVDGVPETVTTATSLLQVLATDCDSGSNAELTYYILSP 294
Query: 349 KGAFSIDPRSGWLTVRNQTVLDREAHSSL-RMKVYAKETN-PSVVGTFADSQRIAKWRRQ 406
FSI P T+ + LD E + L V A + GT R+A +
Sbjct: 295 D--FSISPHG---TIFPASRLDYERPNHLYEFVVMATDGGIEPHSGTATVRVRMANINDE 349
Query: 407 PLETNAPLEKTTY----VFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPS 462
E + P+++++ D G T N ++ + L + +TL+ N F+
Sbjct: 350 APEFSQPVDESSLFLLAFLADVKGQTTRNKSFHIQNLKD--RLVLTLVKLN-----FLCR 402
Query: 463 NLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSV 522
Y + +A T++ V A DPD G ++Y + TS F I+ G + +
Sbjct: 403 --YRTFVSEDAGPNTLVATVLAKDPD-GDG--IIYSI--TSG-NEEGNFVIDSQKGLIRL 454
Query: 523 AESPI--LEG-RHALFVEASDQPANPS-ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPY 578
+P+ L+G + L V A+D A+ + +S A V + V NKP +
Sbjct: 455 RSNPLPKLQGLEYVLNVTATDDNASGGPQPLFSTARVIVGVD-DVNNNKPVFKECQQYRE 513
Query: 579 EFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLHGYEEGVPFAVEERSG-VITVVDDL 635
+ V N GT V Q+ DA E V Y L+H F + +G V T +L
Sbjct: 514 QASVLENQPTGTFVLQVHAVDADEGANGKVKYGLMHRDSAMPAFRIHPDTGRVHTDCQEL 573
Query: 636 S 636
S
Sbjct: 574 S 574
Score = 60.9 bits (141), Expect = 3e-07
Identities = 54/156 (34%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 228 GATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN----- 282
G + Y + SGN+ F +DS G + L + LQ +VL V A+ N
Sbjct: 427 GDGIIYSITSGNEEGNFVIDSQKGLIRLRS----NPLPKLQGLEYVLNVTATDDNASGGP 482
Query: 283 NPLKTAQARVEIELLDLNDNLPEF-EVDFYN--ISIVENLPNGFSVLQVMATDKDQGENG 339
PL + ARV + + D+N+N P F E Y S++EN P G VLQV A D D+G NG
Sbjct: 483 QPLFST-ARVIVGVDDVNNNKPVFKECQQYREQASVLENQPTGTFVLQVHAVDADEGANG 541
Query: 340 EFTYQL---DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
+ Y L D AF I P +G + Q + R+
Sbjct: 542 KVKYGLMHRDSAMPAFRIHPDTGRVHTDCQELSSRD 577
Score = 58.0 bits (134), Expect = 2e-06
Identities = 74/266 (27%), Positives = 113/266 (42%), Gaps = 36/266 (13%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNI----SALDGGNLND--NISVRVFVKDVNDHFPVF 1045
F I G + + R+L ES+ R + ++ + G L+ + V+V + D ND P F
Sbjct: 192 FSIRPETGEISLTRTLDYESDQRRYLLMVRASEEPGILSAAAEVRVQVLITDENDCVPEF 251
Query: 1046 KKTWYNFN-VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSV 1104
++ Y+ + V E T L +V ATD D G NA LTY+I D F ISP G +
Sbjct: 252 LQSIYSVDGVPETVTTATSLLQVLATDCDSGSNAELTYYILSPD----FSISP-HGTIFP 306
Query: 1105 NGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-YAFDE------- 1156
LD E + VV +G ++ND +P+F DE
Sbjct: 307 ASRLDYERPNHLYEFVVMATDGGIEPHSGTATVRVRMANINDEAPEFSQPVDESSLFLLA 366
Query: 1157 -LLEWKHPEADELSNH--NFESVMMIPV--------YKATIEENAPIGTTVAKVFANDTD 1205
L + K S H N + +++ + Y+ + E+A T VA V A D D
Sbjct: 367 FLADVKGQTTRNKSFHIQNLKDRLVLTLVKLNFLCRYRTFVSEDAGPNTLVATVLAKDPD 426
Query: 1206 FIGNGNGLILYSLPQRKNQQNLGLPS 1231
G+G I+YS+ + N + S
Sbjct: 427 --GDG---IIYSITSGNEEGNFVIDS 447
Score = 54.0 bits (124), Expect = 3e-05
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 16/174 (9%)
Query: 734 EDGTIFTQKPLDREK-RDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATY 792
E G I + LD E + Y + V A G++S A +V + I DEND P F + Y
Sbjct: 197 ETGEISLTRTLDYESDQRRYLLMVRASEEPGILSAAAEVRVQVLITDENDCVPEFLQSIY 256
Query: 793 E-GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
+ E T + + ATD D G+NA Y + F + + G + F
Sbjct: 257 SVDGVPETVTTATSLLQ---VLATDCDSGSNAELTYYILSPD---FSISPH-GTI-FPAS 308
Query: 852 SLDREK-KIMYKLSLVARDTGGL---SSEAELIIMIGDENDNKPEFNQ-IEENS 900
LD E+ +Y+ ++A D GG+ S A + + + + ND PEF+Q ++E+S
Sbjct: 309 RLDYERPNHLYEFVVMATD-GGIEPHSGTATVRVRMANINDEAPEFSQPVDESS 361
Score = 52.0 bits (119), Expect = 1e-04
Identities = 26/72 (36%), Positives = 47/72 (65%), Gaps = 3/72 (4%)
Query: 291 RVEIELLDLNDNLPEFEVDFYN-ISIVEN-LPNGFSVLQVMATDKDQGENGEFTYQLDD- 347
+V +++ D+NDN+PE+++ Y +++V + P G V Q+ A D+D+G +GE Y L D
Sbjct: 32 KVRLKITDVNDNIPEWDMKPYPYLAVVSHEAPAGTFVYQLQAHDEDEGRSGEVEYFLSDG 91
Query: 348 PKGAFSIDPRSG 359
G FS++ ++G
Sbjct: 92 GDGCFSVEKKTG 103
Score = 48.4 bits (110), Expect = 0.002
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 8/116 (6%)
Query: 772 QVTIYIEDENDNPPVFEHATYE--GFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTL 829
+V + I D NDN P ++ Y + + GT + ++A D DEG + Y L
Sbjct: 32 KVRLKITDVNDNIPEWDMKPYPYLAVVSHEAPAGTFVYQ---LQAHDEDEGRSGEVEYFL 88
Query: 830 FGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD-TGGLSSEAELIIMIG 884
G F V++ TG V G +L R+++ Y LS+VA D GG S+ A L ++ G
Sbjct: 89 SDGGDGCFSVEKKTGQVVTTGLALQRDRE--YLLSVVALDGLGGRSTPAMLSVVAG 142
Score = 44.0 bits (99), Expect = 0.032
Identities = 46/123 (37%), Positives = 63/123 (51%), Gaps = 15/123 (12%)
Query: 992 FVINERHGHVIVARSLP-PES---EFRLNISALD----GGN--LNDNISVRVFVKDVNDH 1041
FVI+ + G +I RS P P+ E+ LN++A D GG L V V V DVN++
Sbjct: 443 FVIDSQKG-LIRLRSNPLPKLQGLEYVLNVTATDDNASGGPQPLFSTARVIVGVDDVNNN 501
Query: 1042 FPVFKKTWY---NFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLP-FEISP 1097
PVFK+ +V E Q T + +V A DAD G N + Y + D+ +P F I P
Sbjct: 502 KPVFKECQQYREQASVLENQPTGTFVLQVHAVDADEGANGKVKYGLMHRDSAMPAFRIHP 561
Query: 1098 LTG 1100
TG
Sbjct: 562 DTG 564
Score = 39.1 bits (87), Expect = 0.92
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGD 851
Y F+ E++ T + + A D D G ++ T G + F +D G+++ +
Sbjct: 403 YRTFVSEDAGPNTLVAT---VLAKDPD-GDGIIYSITS-GNEEGNFVIDSQKGLIRLRSN 457
Query: 852 SLDREKKIMYKLSLVARD---TGG---LSSEAELIIMIGDENDNKPEFNQIEENSKVRIH 905
L + + + Y L++ A D +GG L S A +I+ + D N+NKP F + ++ +
Sbjct: 458 PLPKLQGLEYVLNVTATDDNASGGPQPLFSTARVIVGVDDVNNNKPVFKECQQYREQASV 517
Query: 906 RETKLNGT 913
E + GT
Sbjct: 518 LENQPTGT 525
Score = 37.9 bits (84), Expect = 2.1
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 772 QVTIYIEDENDNPPVFEHATY---EGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+V + ++D N+N PVF+ + ++EN GT + + A DADEG N Y
Sbjct: 490 RVIVGVDDVNNNKPVFKECQQYREQASVLENQPTGTFVLQ---VHAVDADEGANGKVKYG 546
Query: 829 LFGEGKEM--FDVDENTGVV 846
L M F + +TG V
Sbjct: 547 LMHRDSAMPAFRIHPDTGRV 566
>UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep:
Fc1-cadherin - Folsomia candida
Length = 1565
Score = 83.0 bits (196), Expect = 6e-14
Identities = 107/457 (23%), Positives = 197/457 (43%), Gaps = 41/457 (8%)
Query: 465 YEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQ-RTSNLTITSPFKINPNTGTVSVA 523
Y+ SM + +G V+ ++ A D D G NG V+Y + N F I+ +G +++
Sbjct: 242 YKESMPQDLALGQVVMRISATDIDDGNNGTVVYACEPHPQNPNDVEFFDISSASGEITLK 301
Query: 524 ESPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVG 583
+ + + L + ASD P+ L++V E ++ +P P+F+ P +
Sbjct: 302 KRIGNQQKFQLRIVASDLGVPPNSAITDLSIVVAEPSQ-----RP--PEFINPPTLIHLD 354
Query: 584 SNV-GIGTSVGQIRVNDAFEQNDVSYDLLHGY-----EEGV-PFAVEERSGVITVVDDLS 636
+ + V + + V ++L++G +E + E R+ +D
Sbjct: 355 EYIYNLSVPVATLSARSNADDELVFFELVNGQTQPTNKEAIFTLETEGRNTAHIKLDRQL 414
Query: 637 RYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAA 696
Y + Q NL+ T TV V D NDE+ + ++ + G +
Sbjct: 415 DYESTTRYTLTIRAQNKYNLAAETLLTVMVNDKNDEKPYFTEVTTGTVL---ENEPIGTS 471
Query: 697 IGQIFHTNMSSIYGNGTG-NVRFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRM 754
+ ++ +I +GT N + D D+ +I A G I T+K DRE++D Y++
Sbjct: 472 VMRV-----RAIDTDGTAPNNEVTYHLKSDEEDNFSIDAISGEIKTRKMFDREEKDTYQV 526
Query: 755 TVIA-------EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIK 807
V A + N G + I I D+NDN PVF YE + E++ + +
Sbjct: 527 IVYAKDGAPSVKLNNGQ-PNERPQTLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVV 585
Query: 808 MDNIIKATDADEGTNALFMYTLF-GEGKEMFDV-DENTGVVKFIGDSLDREKKIMYKLSL 865
++A DAD T ++ YT+ G + F + +T V + + LD E Y+L++
Sbjct: 586 E---VRAKDAD--TASVLQYTITEGNIDDAFAIRSTSTSGVITVKNKLDFESIRQYELTV 640
Query: 866 VARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
D+ ++ ++ I I + ND P+F + N+ +
Sbjct: 641 RVSDSVH-EAKTKVKIYIQNVNDEPPKFEPMNSNTTI 676
Score = 72.9 bits (171), Expect = 6e-11
Identities = 110/463 (23%), Positives = 194/463 (41%), Gaps = 46/463 (9%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD-LGQNGMVLYDLQRTSNL 505
V + D ND P F + + ++ N +GT + +V+A+D D N V Y L+
Sbjct: 442 VMVNDKNDEKPYF--TEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTYHLKSDEE- 498
Query: 506 TITSPFKINPNTGTVSVAESPILEGR--HALFVEASD-------QPANPSERRYSLAVVT 556
F I+ +G + + E + + + V A D P+ER +L +V
Sbjct: 499 ---DNFSIDAISGEIKTRKMFDREEKDTYQVIVYAKDGAPSVKLNNGQPNERPQTLKIVI 555
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG-YE 615
+ + G P F+ YE + + + V ++R DA + + Y + G +
Sbjct: 556 AD--KNDNG-----PVFVRDLYEAEMSEDADLNRVVVEVRAKDADTASVLQYTITEGNID 608
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDERGV 675
+ SGVITV + L + Y+ V + ++ + T +++ +VNDE
Sbjct: 609 DAFAIRSTSTSGVITVKNKLDFESIRQYEL-TVRVSDSVH-EAKTKVKIYIQNVNDEPPK 666
Query: 676 LLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED 735
+ I V+E I ++ + N+ + I ++ +D
Sbjct: 667 FEPMNSNTTI--VEEFIPSDCIFRVKAYDPDIGDRTVPQNISYFILTGKEHFS--VGPDD 722
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVI-SGAGIY-QVTIYIEDENDNPPVFEHATYE 793
G + KPLDRE + Y+M V A G+ + Y ++ + + D NDN PV
Sbjct: 723 GCVKVIKPLDREDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPVLSSQNPV 782
Query: 794 GFIMENSKIGTEIKMDNIIKATDADEGTNA-LFMYTLFGEG----KEMFDVDENTGVVKF 848
+ EN G ++D ATDAD N F +++ + KE+F ++ T +K
Sbjct: 783 VW-NENQPRGPITQLD----ATDADSPENGPPFTFSIDPKADMKIKELFSIEGKT--LKA 835
Query: 849 IGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
D DRE+ Y + + D+G + + L ++IGD+NDN
Sbjct: 836 NKDDFDREEVKQYVVPIAISDSGRERKTGTSYLTVIIGDQNDN 878
Score = 66.1 bits (154), Expect = 7e-09
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 22/218 (10%)
Query: 942 ENIPIGTTIIKLNALDLD-SGLNGQIRYEFNSEVYIPPSKLSADAL--EVK--RYFVINE 996
EN PIGT+++++ A+D D + N ++ Y S+ S DA+ E+K + F E
Sbjct: 464 ENEPIGTSVMRVRAIDTDGTAPNNEVTYHLKSD---EEDNFSIDAISGEIKTRKMFDREE 520
Query: 997 RHGHVIVARSLPPESEFRLNISALDGGNLNDNI-SVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ + ++ + +LN G N+ ++++ + D ND+ PVF + Y +
Sbjct: 521 KDTYQVIVYAKDGAPSVKLN-----NGQPNERPQTLKIVIADKNDNGPVFVRDLYEAEMS 575
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI--SPLTGVLSVNGELDRETE 1113
E RV+ +V A DAD + L Y I + D F I + +GV++V +LD E+
Sbjct: 576 EDADLNRVVVEVRAKDADTA--SVLQYTITEGNIDDAFAIRSTSTSGVITVKNKLDFESI 633
Query: 1114 DKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+Y LTV D+ +VND PKF
Sbjct: 634 RQYELTVRVSDS----VHEAKTKVKIYIQNVNDEPPKF 667
Score = 64.1 bits (149), Expect = 3e-08
Identities = 80/346 (23%), Positives = 143/346 (41%), Gaps = 25/346 (7%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+++ + D NDN PVFV +LYE M +A + V+ +V+A D D VL N
Sbjct: 551 LKIVIADKNDNGPVFV-RDLYEAEMSEDADLNRVVVEVRAKDAD---TASVLQYTITEGN 606
Query: 505 LTITSPFKINPNTGTVSVAESPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ + +G ++V E ++ L V SD + ++ + + + +
Sbjct: 607 IDDAFAIRSTSTSGVITVKNKLDFESIRQYELTVRVSDS-VHEAKTKVKIYIQNV----N 661
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
+ K + + E ++ S+ + D ++SY +L G E F+V
Sbjct: 662 DEPPKFEPMNSNTTIVEEFIPSDCIFRVKAYDPDIGDRTVPQNISYFILTGKEH---FSV 718
Query: 623 EERSGVITVVDDLSRYNRPMYDFEAVALQE----NANLSIVTNATVHVVDVNDERGVLLK 678
G + V+ L R ++P Y A E L V+++D+ND VL
Sbjct: 719 GPDDGCVKVIKPLDREDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPVL-- 776
Query: 679 GAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTI 738
+ +P++++ EN I Q+ T+ S NG F I + D+ + +G
Sbjct: 777 SSQNPVVWN--ENQPRGPITQLDATDADS-PENGP-PFTFSIDPKADMKIKELFSIEGKT 832
Query: 739 FTQKPLDREKRDVYRMTV-IAEFNKGVISGAGIYQVTIYIEDENDN 783
D ++ +V + V IA + G G +T+ I D+NDN
Sbjct: 833 LKANKDDFDREEVKQYVVPIAISDSGRERKTGTSYLTVIIGDQNDN 878
Score = 60.5 bits (140), Expect = 3e-07
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 233 YELISG-----NDRKLFSLDSVNGSLFLEKELDLDAEHNLQANT-FVLQVQASQLNNPLK 286
+EL++G N +F+L++ + + LD + + ++ T + L ++A N
Sbjct: 380 FELVNGQTQPTNKEAIFTLETEGRNT---AHIKLDRQLDYESTTRYTLTIRAQNKYN--L 434
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD-QGENGEFTYQL 345
A+ + + + D ND P F + +++EN P G SV++V A D D N E TY L
Sbjct: 435 AAETLLTVMVNDKNDEKPYF-TEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTYHL 493
Query: 346 -DDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
D + FSID SG ++ + + DRE + ++ VYAK+ PSV
Sbjct: 494 KSDEEDNFSIDAISG--EIKTRKMFDREEKDTYQVIVYAKDGAPSV 537
Score = 58.0 bits (134), Expect = 2e-06
Identities = 96/365 (26%), Positives = 147/365 (40%), Gaps = 37/365 (10%)
Query: 546 SERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA---FE 602
++ +Y+LA T+ +K D + V N IGTSV ++R D
Sbjct: 428 AQNKYNLAAETLLTVM--VNDKNDEKPYFTEVTTGTVLENEPIGTSVMRVRAIDTDGTAP 485
Query: 603 QNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNA 662
N+V+Y L E+ F+++ SG I R + Y A ++ A + N
Sbjct: 486 NNEVTYHLKSDEEDN--FSIDAISGEIKTRKMFDREEKDTYQVIVYA-KDGAPSVKLNNG 542
Query: 663 TVHVVDVNDERGVLLKGAHSPII---FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFL 719
+ + + K + P+ + E S A + ++ + T +V
Sbjct: 543 QPNERPQTLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVVEVRAK--DADTASVLQY 600
Query: 720 IANQQDVTDDIAI---AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
+ ++ D AI + G I + LD E Y +TV + V +V IY
Sbjct: 601 TITEGNIDDAFAIRSTSTSGVITVKNKLDFESIRQYELTV--RVSDSVHEAKT--KVKIY 656
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNI--IKATDADEGTNAL---FMYTLFG 831
I++ ND PP FE I+E I D I +KA D D G + Y +
Sbjct: 657 IQNVNDEPPKFEPMNSNTTIVEEF-----IPSDCIFRVKAYDPDIGDRTVPQNISYFIL- 710
Query: 832 EGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSE-----AELIIMIGDE 886
GKE F V + G VK I LDRE K Y++ + A D GL+ ELI+ + D
Sbjct: 711 TGKEHFSVGPDDGCVKVI-KPLDREDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDI 769
Query: 887 NDNKP 891
NDN P
Sbjct: 770 NDNAP 774
Score = 50.8 bits (116), Expect = 3e-04
Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 31/178 (17%)
Query: 218 IHAIDQDLGV-GATLRYELISGNDRKL-FSLDSVNGSLFLEKELDLDAEHNLQANTFVLQ 275
+ A+DQD G T+ Y ++SGN+ F++D G + K D D E + +V
Sbjct: 128 VKALDQDPPESGGTVTYSIVSGNEMLADFAVDEHTGWISTRKIFDRD-EPAKEKEVYVT- 185
Query: 276 VQASQLNNPLKTAQARVEIELLDLNDN---------------LPEFEVD------FYNIS 314
VQAS NP A +++++ D+NDN +PE E + Y S
Sbjct: 186 VQASDNGNPRLDAVCTLKVKITDINDNTAQFLLSRRFNQGSYVPEHEYNPHLDKYEYKES 245
Query: 315 IVENLPNGFSVLQVMATDKDQGENGEFTYQLD----DPKGA--FSIDPRSGWLTVRNQ 366
+ ++L G V+++ ATD D G NG Y + +P F I SG +T++ +
Sbjct: 246 MPQDLALGQVVMRISATDIDDGNNGTVVYACEPHPQNPNDVEFFDISSASGEITLKKR 303
Score = 48.4 bits (110), Expect = 0.002
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 6/169 (3%)
Query: 218 IHAIDQD-LGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQV 276
+ AID D + Y L S + FS+D+++G + K D + + Q +
Sbjct: 475 VRAIDTDGTAPNNEVTYHLKSDEEDN-FSIDAISGEIKTRKMFDREEKDTYQVIVYAKDG 533
Query: 277 QAS-QLNNPLKTAQAR-VEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
S +LNN + + ++I + D NDN P F D Y + E+ V++V A D D
Sbjct: 534 APSVKLNNGQPNERPQTLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDAD 593
Query: 335 QGENGEFTYQLDDPKGAFSI--DPRSGWLTVRNQTVLDREAHSSLRMKV 381
++T + AF+I SG +TV+N+ + L ++V
Sbjct: 594 TASVLQYTITEGNIDDAFAIRSTSTSGVITVKNKLDFESIRQYELTVRV 642
Score = 47.2 bits (107), Expect = 0.003
Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 11/166 (6%)
Query: 223 QDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLN 282
+D + L+Y + GN F++ S + S + + LD E Q + L V+ S
Sbjct: 590 KDADTASVLQYTITEGNIDDAFAIRSTSTSGVITVKNKLDFESIRQ---YELTVRVSDSV 646
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN---G 339
+ KT +V+I + ++ND P+FE N +IVE + +V A D D G+
Sbjct: 647 HEAKT---KVKIYIQNVNDEPPKFEPMNSNTTIVEEFIPSDCIFRVKAYDPDIGDRTVPQ 703
Query: 340 EFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+Y + K FS+ P G + V LDRE +M V A +
Sbjct: 704 NISYFILTGKEHFSVGPDDGCVKVIKP--LDREDKPFYQMVVGASD 747
Score = 46.4 bits (105), Expect = 0.006
Identities = 85/388 (21%), Positives = 157/388 (40%), Gaps = 56/388 (14%)
Query: 784 PPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM---FDVD 840
P + +Y I E + T + +KA D D + + G EM F VD
Sbjct: 103 PDFVDCGSYRPSIPEGEPVDTPVIQ---VKALDQDPPESGGTVTYSIVSGNEMLADFAVD 159
Query: 841 ENTGVVK----FIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFN 894
E+TG + F D +EK++ +++ A D G L + L + I D NDN +F
Sbjct: 160 EHTGWISTRKIFDRDEPAKEKEVY--VTVQASDNGNPRLDAVCTLKVKITDINDNTAQF- 216
Query: 895 QIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLN 954
+ R F P++++ +D+ +P+++ +G +++++
Sbjct: 217 --------LLSRR--------FNQGSYVPEHEYNPHLDKYEYKESMPQDLALGQVVMRIS 260
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFR 1014
A D+D G NG + Y P + + +E +F I+ G + + + + + +F+
Sbjct: 261 ATDIDDGNNGTVVYA------CEPHPQNPNDVE---FFDISSASGEITLKKRIGNQQKFQ 311
Query: 1015 LNISALD-GGNLNDNIS-VRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDA 1072
L I A D G N I+ + + V + + P F +++E Y V V A
Sbjct: 312 LRIVASDLGVPPNSAITDLSIVVAEPSQRPPEFINPPTLIHLDEYIYNLSV--PVATLSA 369
Query: 1073 DFGQNANLTYF------IQPSDTDLPFEISP---LTGVLSVNGELDRETEDKYILTVVAR 1123
+ L +F QP++ + F + T + ++ +LD E+ +Y LT+ A+
Sbjct: 370 RSNADDELVFFELVNGQTQPTNKEAIFTLETEGRNTAHIKLDRQLDYESTTRYTLTIRAQ 429
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ D ND P F
Sbjct: 430 NK---YNLAAETLLTVMVNDKNDEKPYF 454
Score = 45.2 bits (102), Expect = 0.014
Identities = 61/250 (24%), Positives = 109/250 (43%), Gaps = 22/250 (8%)
Query: 996 ERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDV--NDHFPVFKKTW-YNF 1052
+RHG I ++PP+ F+ ++ GG+ ++ K + N H P F Y
Sbjct: 59 KRHGREI---NIPPQ--FQSYVADNRGGDGFSFTPIQPEEKSMHQNLHKPDFVDCGSYRP 113
Query: 1053 NVEEAQYTRRVLGKVDATDADFGQNAN-LTYFIQPSDTDLP-FEISPLTGVLSVNGELDR 1110
++ E + + +V A D D ++ +TY I + L F + TG +S DR
Sbjct: 114 SIPEGEPVDTPVIQVKALDQDPPESGGTVTYSIVSGNEMLADFAVDEHTGWISTRKIFDR 173
Query: 1111 ET---EDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
+ E + +TV A DNG D+NDN+ +F LL + +
Sbjct: 174 DEPAKEKEVYVTVQASDNGNPRLDAVCTLKVKIT-DINDNTAQF-----LLSRRFNQGSY 227
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSL-PQRKNQQN 1226
+ H + + YK ++ ++ +G V ++ A D D GN NG ++Y+ P +N +
Sbjct: 228 VPEHEYNPHLDKYEYKESMPQDLALGQVVMRISATDID-DGN-NGTVVYACEPHPQNPND 285
Query: 1227 LGLPSLSSTA 1236
+ +SS +
Sbjct: 286 VEFFDISSAS 295
Score = 45.2 bits (102), Expect = 0.014
Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 10/158 (6%)
Query: 999 GHVIVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEE 1056
G + V L ES ++ L + D + V++++++VND P F+ N + E
Sbjct: 620 GVITVKNKLDFESIRQYELTVRVSDSVH-EAKTKVKIYIQNVNDEPPKFEPMNSNTTIVE 678
Query: 1057 AQYTRRVLGKVDATDADFGQNA---NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETE 1113
+ +V A D D G N++YFI F + P G + V LDRE +
Sbjct: 679 EFIPSDCIFRVKAYDPDIGDRTVPQNISYFILTGKEH--FSVGPDDGCVKVIKPLDREDK 736
Query: 1114 DKYILTVVARDNG--XXXXXXXXXXXXXXXXDVNDNSP 1149
Y + V A D D+NDN+P
Sbjct: 737 PFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAP 774
Score = 38.3 bits (85), Expect = 1.6
Identities = 64/282 (22%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 82 SVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRG-LTI 140
++ + I D NDN P+F+ Y + E + + T+ G +
Sbjct: 550 TLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDADTASVLQYTITEGNIDD 609
Query: 141 FKDIRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPVLLLRKVLDYDAGDKEFQLV 200
IR+ T + + + + + +S H+ + K+ + D+ +
Sbjct: 610 AFAIRSTSTSGVITVKNKLDFESIRQYELTVRVSDSVHEAKTKV-KIYIQNVNDEPPKFE 668
Query: 201 IMASGKRIHKEILFPEPIH---AIDQDLG---VGATLRYELISGNDRKLFSLDSVNGSLF 254
M S I +E + + I A D D+G V + Y +++G + FS+ +G +
Sbjct: 669 PMNSNTTIVEEFIPSDCIFRVKAYDPDIGDRTVPQNISYFILTGKEH--FSVGPDDGCVK 726
Query: 255 LEKELDLDAEHNLQANTFVLQVQASQLNNPLKTA-QARVEIELLDLNDNLPEFEVDFYNI 313
+ K LD + + Q V+ P K + + L+D+NDN P +
Sbjct: 727 VIKPLDREDKPFYQ---MVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPVLSSQ-NPV 782
Query: 314 SIVENLPNGFSVLQVMATDKDQGENG-EFTYQLDDPKGAFSI 354
EN P G + Q+ ATD D ENG FT+ + DPK I
Sbjct: 783 VWNENQPRG-PITQLDATDADSPENGPPFTFSI-DPKADMKI 822
Score = 37.1 bits (82), Expect = 3.7
Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 9/88 (10%)
Query: 292 VEIELLDLNDNL--PEF-EVDFYNISIVENLPNGFSVLQVMATDKDQGEN-GEFTYQL-- 345
++ E ++ NL P+F + Y SI E P V+QV A D+D E+ G TY +
Sbjct: 89 IQPEEKSMHQNLHKPDFVDCGSYRPSIPEGEPVDTPVIQVKALDQDPPESGGTVTYSIVS 148
Query: 346 -DDPKGAFSIDPRSGWLTVRNQTVLDRE 372
++ F++D +GW++ R + DR+
Sbjct: 149 GNEMLADFAVDEHTGWISTRK--IFDRD 174
>UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadherin
beta 20; n=2; Gallus gallus|Rep: PREDICTED: similar to
protocadherin beta 20 - Gallus gallus
Length = 808
Score = 82.6 bits (195), Expect = 8e-14
Identities = 53/165 (32%), Positives = 81/165 (49%), Gaps = 8/165 (4%)
Query: 741 QKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENS 800
+KPLDRE++ T++A + G G ++ I + D NDN PVF Y G ++EN+
Sbjct: 351 EKPLDREEQSELDFTLVAT-DGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENA 409
Query: 801 KIGTEIKMDNIIKATDADEGTNALFMYTLF---GEGKEMFDVDENTGVVKFIGDSLDREK 857
G+ + + A DADEG N Y G +F ++ TG + I LD E
Sbjct: 410 PEGSVVLR---VVANDADEGVNGDISYQFSQSAGHSHSLFTINSRTGEI-VIAKPLDFET 465
Query: 858 KIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
++ ++ A D GG SS +++ + D NDN PE NS +
Sbjct: 466 AQKHEFTVQAIDGGGFSSMCNVVVEVLDVNDNAPEIAVTSFNSPI 510
Score = 72.5 bits (170), Expect = 8e-11
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 19/190 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN P G+ ++++ A D D G+NG I Y+F S A F IN R G +
Sbjct: 407 ENAPEGSVVLRVVANDADEGVNGDISYQF-----------SQSAGHSHSLFTINSRTGEI 455
Query: 1002 IVARSLPPES--EFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQY 1059
++A+ L E+ + + A+DGG + +V V V DVND+ P T +N + E
Sbjct: 456 VIAKPLDFETAQKHEFTVQAIDGGGFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVE 515
Query: 1060 TRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTG---VLSVNGELDRETEDKY 1116
V+ + +D D G N +T + + L F + P L LDRE ++
Sbjct: 516 PGTVVALLAVSDQDSGVNGEITCAL---EEQLYFALRPAFKNYYELVTVSTLDREERAQH 572
Query: 1117 ILTVVARDNG 1126
++ V A D G
Sbjct: 573 MVVVTAADAG 582
Score = 71.7 bits (168), Expect = 1e-10
Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 12/151 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGS---LFLEKELDLDAEHNLQANTFVLQV 276
A D D+G Y +I N+ S + L LEK LD + + L F L
Sbjct: 312 AQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLDREEQSELD---FTLV- 367
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A+ +P +T + I +LD+NDN+P F Y ++EN P G VL+V+A D D+G
Sbjct: 368 -ATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENAPEGSVVLRVVANDADEG 426
Query: 337 ENGEFTYQLDDPKG----AFSIDPRSGWLTV 363
NG+ +YQ G F+I+ R+G + +
Sbjct: 427 VNGDISYQFSQSAGHSHSLFTINSRTGEIVI 457
Score = 70.9 bits (166), Expect = 2e-10
Identities = 53/186 (28%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 220 AIDQDLGVGATLRYELI--SGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
A D D GV + Y+ +G+ LF+++S G + + K LD + Q + F +Q
Sbjct: 420 ANDADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPLDFETA---QKHEFTVQA- 475
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
++ ++ V +E+LD+NDN PE V +N I+EN+ G V + +D+D G
Sbjct: 476 ---IDGGGFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGTVVALLAVSDQDSGV 532
Query: 338 NGEFTYQLDDPKGAFSIDPR-SGWLTVRNQTVLDREAHSSLRMKVYAKET-NPSVVGTFA 395
NGE T L++ + F++ P + + + LDRE + + V A + +P + T
Sbjct: 533 NGEITCALEE-QLYFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHT 591
Query: 396 DSQRIA 401
S I+
Sbjct: 592 FSVDIS 597
Score = 62.5 bits (145), Expect = 9e-08
Identities = 63/219 (28%), Positives = 95/219 (43%), Gaps = 19/219 (8%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER 997
F IPE GT A DLD G N Y IP ++ + + + +
Sbjct: 295 FKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSI-----IPENEFFTVFTQSE-----SSK 344
Query: 998 HGHVIVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFN 1053
+ +++ + L E SE + A DGG+ + + + V D+ND+ PVF + Y +
Sbjct: 345 YVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGH 404
Query: 1054 VEEAQYTRRVLGKVDATDADFGQNANLTYFIQPS--DTDLPFEISPLTGVLSVNGELDRE 1111
V E V+ +V A DAD G N +++Y S + F I+ TG + + LD E
Sbjct: 405 VLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPLDFE 464
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPK 1150
T K+ TV A D G DVNDN+P+
Sbjct: 465 TAQKHEFTVQAIDGG---GFSSMCNVVVEVLDVNDNAPE 500
Score = 60.9 bits (141), Expect = 3e-07
Identities = 79/351 (22%), Positives = 138/351 (39%), Gaps = 26/351 (7%)
Query: 440 MSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDL 499
+ F +EV++ D ND++PVF P F + + GT A D D+G N + Y +
Sbjct: 269 LQFFPIEVSVEDINDHSPVF-PDERVTFKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSI 327
Query: 500 QRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPANPSERRYSLAVVT 556
N T + + V E P+ + + A+D + P + +V
Sbjct: 328 -IPENEFFTVFTQSESSKYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVV 386
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE--QNDVSYDLLH-- 612
+++ ++P F Y V N G+ V ++ NDA E D+SY
Sbjct: 387 LDI-------NDNVPVFTQKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSA 439
Query: 613 GYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDE 672
G+ + F + R+G I + L ++F A+ + S + N V V+DVND
Sbjct: 440 GHSHSL-FTINSRTGEIVIAKPLDFETAQKHEFTVQAI-DGGGFSSMCNVVVEVLDVNDN 497
Query: 673 R-GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIA 731
+ + +SPI+ +V+ + A + +S G + + Q A
Sbjct: 498 APEIAVTSFNSPILENVEPGTVVALLA------VSDQDSGVNGEITCALEEQLYFALRPA 551
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ T LDRE+R M V+ + G + ++ I D N+
Sbjct: 552 FKNYYELVTVSTLDREER-AQHMVVVTAADAGSPPLTSTHTFSVDISDVNE 601
Score = 58.4 bits (135), Expect = 1e-06
Identities = 68/246 (27%), Positives = 108/246 (43%), Gaps = 21/246 (8%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSN 504
+ + +LD NDN PVF LY + NA G+V+ +V A D D G NG + Y +++
Sbjct: 382 IHIVVLDINDNVPVFT-QKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAG 440
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
+ S F IN TG + +A+ E +H V+A D S+ V +EV
Sbjct: 441 HS-HSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGGGFS-----SMCNVVVEVL-D 493
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAV 622
N P+I + + NV GT V + V+D + + V+ ++ EE + FA+
Sbjct: 494 VNDNAPEI---AVTSFNSPILENVEPGTVVALLAVSD--QDSGVNGEITCALEEQLYFAL 548
Query: 623 E---ERSGVITVVDDLSRYNRPMYDFEAVALQENA-NLSIVTNATVHVVDVND--ERGVL 676
+ + V L R R + A + L+ +V + DVN+ E G+
Sbjct: 549 RPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNEATEPGLF 608
Query: 677 LKGAHS 682
GA S
Sbjct: 609 AVGAQS 614
Score = 58.0 bits (134), Expect = 2e-06
Identities = 47/165 (28%), Positives = 75/165 (45%), Gaps = 8/165 (4%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
G + + LDRE+ T F + + + + +ED ND+ PVF
Sbjct: 237 GRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFK 296
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK--EMFDVDENTGVVKFIGDS- 852
I E S GT + A D D G+N + Y++ E + +F E++ V+ + +
Sbjct: 297 IPETSDPGTRFPVG---AAQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKP 353
Query: 853 LDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQ 895
LDRE++ +LVA D G + E+ I++ D NDN P F Q
Sbjct: 354 LDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQ 398
Score = 50.8 bits (116), Expect = 3e-04
Identities = 78/348 (22%), Positives = 139/348 (39%), Gaps = 20/348 (5%)
Query: 604 NDV-SYDLLHGYEEGVPFAVEERSGVITVVDD--LSRYNRPMYDFEAVALQENANLSIVT 660
ND+ +Y ++ E F E S + +V + L R + DF VA + +
Sbjct: 320 NDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLDREEQSELDFTLVAT-DGGSPPRTG 378
Query: 661 NATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+ +H+V D+ND V + + I HV EN+ ++ N + NG + +F
Sbjct: 379 STEIHIVVLDINDNVPVFTQKLY---IGHVLENAPEGSVVLRVVANDADEGVNGDISYQF 435
Query: 719 LIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE 778
+ + + G I KPLD E + TV A G S + V + +
Sbjct: 436 SQSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGGGFSS---MCNVVVEVL 492
Query: 779 DENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFD 838
D NDN P ++ I+EN + GT + ++ +D D G N L +
Sbjct: 493 DVNDNAPEIAVTSFNSPILENVEPGTVVA---LLAVSDQDSGVNGEITCALEEQLYFALR 549
Query: 839 VDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIGDEND-NKPEFNQ 895
+LDRE++ + + + A D G L+S + I D N+ +P
Sbjct: 550 PAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNEATEPGLFA 609
Query: 896 I-EENSKVRIHR-ETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
+ ++ +VR+ R T+ + ++ V+ + L + L+P
Sbjct: 610 VGAQSGEVRLRRPPTERDAAKQKLVVLVRDNGRPPLSATAALSVLLVP 657
Score = 47.2 bits (107), Expect = 0.003
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 18/208 (8%)
Query: 959 DSGLNGQIRYEFNSEVYIPPSKLSADALEV-----KRYFVINERHGHVIVARSLPPESEF 1013
+ G +G + + + + P++LSA + +++F + G ++VA L E
Sbjct: 192 EEGESGSVVADVAEDAGLAPAQLSARRARIASPAGRQHFRLERGSGRLVVAERLDREEMC 251
Query: 1014 RLNISALDGGNL--NDNIS---VRVFVKDVNDHFPVFKKTWYNFNVEEAQ--YTRRVLGK 1066
+ + L D + + V V+D+NDH PVF F + E TR +G
Sbjct: 252 GRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPETSDPGTRFPVGA 311
Query: 1067 VDATDADFGQNANLTYFIQPSD---TDLPFEISPLTGVLSVNGELDRETEDKYILTVVAR 1123
A D D G N Y I P + T S L + LDRE + + T+VA
Sbjct: 312 --AQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLDREEQSELDFTLVAT 369
Query: 1124 DNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
D G D+NDN P F
Sbjct: 370 DGG-SPPRTGSTEIHIVVLDINDNVPVF 396
>UniRef50_Q68SP4 Cluster: Cadherin 5; n=3; Danio rerio|Rep: Cadherin
5 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 767
Score = 82.6 bits (195), Expect = 8e-14
Identities = 109/442 (24%), Positives = 191/442 (43%), Gaps = 45/442 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD--LGQNGMVLYDLQRTSN 504
+ +LD NDN PVF + S+ +++ GT I KVKA D D +NG + + L
Sbjct: 143 IVVLDINDNIPVF--DSDQSGSISESSRAGTTIMKVKATDADDSSTENGRIDFKL----- 195
Query: 505 LTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVTIEVTRG 562
L T FKI PN +++ E ++ + V+A D P + + + VVTI +
Sbjct: 196 LNGTDLFKIKPNGDLIALKSDLDREKQSQYLIAVQAKDMPEHLTGNS-ATTVVTINI--- 251
Query: 563 TKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QN-DVSYDLLHGYEEGVPF 620
K +I F Y+F V ++ G+ +G + V D E QN D ++ L + +
Sbjct: 252 -KDINDNIATFKKERYQFTVKEDLKPGSEIGLLEVEDKDEIQNKDPTFALQSKFNDVFDI 310
Query: 621 -AVEERSGVITVVDDLSRYNRPMYDFEAVALQ-------ENANLSIVTNATVHVVDVNDE 672
+E+ G++++ L + F + + +N L T + V DV DE
Sbjct: 311 KRTKEKDGMLSLKVPLDYEKEKTHKFIVIVEEHTVSRTPDNKGLLKRTEVIIDVTDV-DE 369
Query: 673 RGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI 732
+ + ++ +F + IG + + S + +R+ I + D +
Sbjct: 370 PPIFNQTEYTFSVF--EGPFKNPVIGAVSAKDPDS----ASYKIRYTIEDANCPVDVDPV 423
Query: 733 AEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNPPVFEHAT 791
+G + ++ LDRE+ +Y V A ++ V++G V++ + D NDN P + +
Sbjct: 424 --NGYLSLKRTLDREQESLYTFQVTA--HEDVLNGLKSSTMVSLKVLDINDNAPELTNGS 479
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGK--EMFDVDENTGVVKFI 849
Y ++ EN K T I I A+D DE + F +TL + ++D +NT +
Sbjct: 480 YV-YVCENDKPNTII---GTIGASDKDENSGR-FRFTLARKSSNFSLYDNQDNTATIVLK 534
Query: 850 GDSLDREKKIMYKLSLVARDTG 871
E Y L + D G
Sbjct: 535 QGGFSTENSEEYVLEIEIADGG 556
Score = 66.9 bits (156), Expect = 4e-09
Identities = 81/320 (25%), Positives = 135/320 (42%), Gaps = 31/320 (9%)
Query: 589 GTSVGQIRVNDA----FEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYD 644
GT++ +++ DA E + + LL+G + F ++ +I + DL R + Y
Sbjct: 170 GTTIMKVKATDADDSSTENGRIDFKLLNGTDL---FKIKPNGDLIALKSDLDREKQSQYL 226
Query: 645 FEAVALQENANL---SIVTNATVHVVDVNDERGVLLKGAHSPIIFHVKEN-SAGAAIGQI 700
A +L S T T+++ D+ND K + F VKE+ G+ IG +
Sbjct: 227 IAVQAKDMPEHLTGNSATTVVTINIKDINDNIATFKKERYQ---FTVKEDLKPGSEIGLL 283
Query: 701 FHTNMSSIYGNGTGNVRFLIANQ-QDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIA 758
+ I + F + ++ DV D E DG + + PLD EK ++ VI
Sbjct: 284 EVEDKDEIQNK---DPTFALQSKFNDVFDIKRTKEKDGMLSLKVPLDYEKEKTHKFIVIV 340
Query: 759 EFN--KGVISGAGIYQVTIYIED--ENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKA 814
E + G+ + T I D + D PP+F Y + E I + A
Sbjct: 341 EEHTVSRTPDNKGLLKRTEVIIDVTDVDEPPIFNQTEYTFSVFEGPFKNPVI---GAVSA 397
Query: 815 TDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT--GG 872
D D + + YT+ + DVD G + + +LDRE++ +Y + A + G
Sbjct: 398 KDPDSASYKI-RYTI-EDANCPVDVDPVNGYLS-LKRTLDREQESLYTFQVTAHEDVLNG 454
Query: 873 LSSEAELIIMIGDENDNKPE 892
L S + + + D NDN PE
Sbjct: 455 LKSSTMVSLKVLDINDNAPE 474
Score = 65.7 bits (153), Expect = 9e-09
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 29/317 (9%)
Query: 596 RVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN 655
++ + F + Y +L G F V + +G I V+ L R + +Y+ A L +
Sbjct: 75 KLENTFFSSSTRY-ILKGDGAKDKFGVTD-NGDIVVLAKLDRETQSVYNLSASLLNIHTG 132
Query: 656 LSIVTNAT--VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGT 713
+ + + + V+D+ND V I + + AG I ++ T+
Sbjct: 133 ELVDKDESFVIVVLDINDNIPVFDSDQSGSIS---ESSRAGTTIMKVKATDADDS-STEN 188
Query: 714 GNVRFLIANQQDVTDDIAIAEDGTIFTQKP-LDREKRDVYRMTVIAEFNKGVISG-AGIY 771
G + F + N TD I +G + K LDREK+ Y + V A+ ++G +
Sbjct: 189 GRIDFKLLNG---TDLFKIKPNGDLIALKSDLDREKQSQYLIAVQAKDMPEHLTGNSATT 245
Query: 772 QVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFG 831
VTI I+D NDN F+ Y+ + E+ K G+EI +++ D DE N + L
Sbjct: 246 VVTINIKDINDNIATFKKERYQFTVKEDLKPGSEI---GLLEVEDKDEIQNKDPTFALQS 302
Query: 832 EGKEMFDV---DENTGVVKFIGDSLDREKKIMYKLSLVAR--------DTGGLSSEAELI 880
+ ++FD+ E G++ + LD EK+ +K ++ D GL E+I
Sbjct: 303 KFNDVFDIKRTKEKDGMLS-LKVPLDYEKEKTHKFIVIVEEHTVSRTPDNKGLLKRTEVI 361
Query: 881 IMIGDENDNKPEFNQIE 897
I + D D P FNQ E
Sbjct: 362 IDVTDV-DEPPIFNQTE 377
Score = 65.3 bits (152), Expect = 1e-08
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 21/265 (7%)
Query: 867 ARDTGGLSSEAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNK 926
A+D G++ +++++ + + + +N S + IH ++ F I+ + +
Sbjct: 94 AKDKFGVTDNGDIVVLAKLDRETQSVYNL--SASLLNIHTGELVDKDESFVIVVLDINDN 151
Query: 927 FAL-DVDQLGPLFLIPENIPIGTTIIKLNALDLD--SGLNGQIRYEFNSEVYIPPSKLSA 983
+ D DQ G I E+ GTTI+K+ A D D S NG+I ++ + + K +
Sbjct: 152 IPVFDSDQSGS---ISESSRAGTTIMKVKATDADDSSTENGRIDFKLLNGTDLFKIKPNG 208
Query: 984 DALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGGNLNDNISVRVFVKDVNDHFP 1043
D + +K + E+ ++A E L G + +++ + KD+ND+
Sbjct: 209 DLIALKSD-LDREKQSQYLIAVQAKDMPEH------LTGNSATTVVTINI--KDINDNIA 259
Query: 1044 VFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEI---SPLTG 1100
FKK Y F V+E +G ++ D D QN + T+ +Q D+ F+I G
Sbjct: 260 TFKKERYQFTVKEDLKPGSEIGLLEVEDKDEIQNKDPTFALQSKFNDV-FDIKRTKEKDG 318
Query: 1101 VLSVNGELDRETEDKYILTVVARDN 1125
+LS+ LD E E + V+ ++
Sbjct: 319 MLSLKVPLDYEKEKTHKFIVIVEEH 343
Score = 63.7 bits (148), Expect = 4e-08
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 1021 DGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANL 1080
D L V + V DV D P+F +T Y F+V E + V+G V A D D + +
Sbjct: 350 DNKGLLKRTEVIIDVTDV-DEPPIFNQTEYTFSVFEGPFKNPVIGAVSAKDPD-SASYKI 407
Query: 1081 TYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXX 1140
Y I+ D + P ++ P+ G LS+ LDRE E Y V A ++
Sbjct: 408 RYTIE--DANCPVDVDPVNGYLSLKRTLDREQESLYTFQVTAHED-VLNGLKSSTMVSLK 464
Query: 1141 XXDVNDNSPK 1150
D+NDN+P+
Sbjct: 465 VLDINDNAPE 474
Score = 58.4 bits (135), Expect = 1e-06
Identities = 49/183 (26%), Positives = 86/183 (46%), Gaps = 11/183 (6%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
PE I ++ +T RY L + F + NG + + +LD + + + +L
Sbjct: 70 PEKIGKLENTFFSSST-RYILKGDGAKDKFGVTD-NGDIVVLAKLDRETQSVYNLSASLL 127
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD 334
+ +L + ++ I +LD+NDN+P F+ D + SI E+ G ++++V ATD D
Sbjct: 128 NIHTGELVDKDES----FVIVVLDINDNIPVFDSD-QSGSISESSRAGTTIMKVKATDAD 182
Query: 335 QG--ENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSVVG 392
ENG ++L + F I P + +++ LDRE S + V AK+ + G
Sbjct: 183 DSSTENGRIDFKLLNGTDLFKIKPNGDLIALKSD--LDREKQSQYLIAVQAKDMPEHLTG 240
Query: 393 TFA 395
A
Sbjct: 241 NSA 243
Score = 49.2 bits (112), Expect = 9e-04
Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 9/115 (7%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPL--KTAQA 290
++L++G D LF + NG L K DLD E Q +++ VQA + L +A
Sbjct: 193 FKLLNGTD--LFKIKP-NGDLIALKS-DLDREKQSQ---YLIAVQAKDMPEHLTGNSATT 245
Query: 291 RVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL 345
V I + D+NDN+ F+ + Y ++ E+L G + + DKD+ +N + T+ L
Sbjct: 246 VVTINIKDINDNIATFKKERYQFTVKEDLKPGSEIGLLEVEDKDEIQNKDPTFAL 300
Score = 46.0 bits (104), Expect = 0.008
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQ-LNNPLKTAQARVEIELLDLNDNLP 304
+D VNG L L++ LD + E + + QV A + + N LK++ V +++LD+NDN P
Sbjct: 420 VDPVNGYLSLKRTLDREQE-----SLYTFQVTAHEDVLNGLKSS-TMVSLKVLDINDNAP 473
Query: 305 EFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSI 354
E Y + + EN + + A+DKD+ +G F + L FS+
Sbjct: 474 ELTNGSY-VYVCENDKPNTIIGTIGASDKDE-NSGRFRFTLARKSSNFSL 521
Score = 37.1 bits (82), Expect = 3.7
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Query: 250 NGSLFLEKELDLDAEHNLQANTFVLQVQASQL-NNPLKTAQARVEIELLDLNDNLPEFEV 308
+G L L+ LD + E + V + S+ +N + V I++ D+ D P F
Sbjct: 317 DGMLSLKVPLDYEKEKTHKFIVIVEEHTVSRTPDNKGLLKRTEVIIDVTDV-DEPPIFNQ 375
Query: 309 DFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTV 368
Y S+ E + V A D D + Y ++D +DP +G+L+++
Sbjct: 376 TEYTFSVFEGPFKNPVIGAVSAKDPDSASY-KIRYTIEDANCPVDVDPVNGYLSLKR--T 432
Query: 369 LDREAHSSLRMKVYAKE 385
LDRE S +V A E
Sbjct: 433 LDREQESLYTFQVTAHE 449
>UniRef50_Q7YWB8 Cluster: Cadherin-like protein cad3; n=1; Aplysia
californica|Rep: Cadherin-like protein cad3 - Aplysia
californica (California sea hare)
Length = 416
Score = 82.6 bits (195), Expect = 8e-14
Identities = 48/143 (33%), Positives = 72/143 (50%), Gaps = 1/143 (0%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEK-ELDLDAEHNLQANTFVLQV 276
I A D D G T+ Y + SGN++ +F LD L L + + + + + L V
Sbjct: 117 ITASDPDGGNNGTVSYRIASGNEKGMFGLDFTGLPLILYLVKRGSEGFDREKLDYYELVV 176
Query: 277 QASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
A P + V + +LD+NDN P F++ Y + E+ P G SV + ATD+D G
Sbjct: 177 SACDGGVPPLCTELTVGVNILDVNDNTPAFDLSDYTTQVNESAPVGSSVFRAEATDEDIG 236
Query: 337 ENGEFTYQLDDPKGAFSIDPRSG 359
NGE +Y+L+D F ID +G
Sbjct: 237 LNGEVSYRLEDESNQFKIDENTG 259
Score = 68.1 bits (159), Expect = 2e-09
Identities = 78/296 (26%), Positives = 127/296 (42%), Gaps = 25/296 (8%)
Query: 626 SGVITVVDDLSRYNRP--MYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLKGAHS 682
SG + +D + R + P + V S VT + + V+DVND R +
Sbjct: 40 SGTLRTLDSIDRESIPESLVRLFVVGTPPTTLDSQVTFSVVITVLDVNDNRPDFQVDDNK 99
Query: 683 PIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQK 742
II ++ G I ++ NGT + R N++ + ++ K
Sbjct: 100 EIIAFQEDAREGRTKSIITASDPDG-GNNGTVSYRIASGNEKGMFGLDFTGLPLILYLVK 158
Query: 743 P----LDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIME 798
DREK D Y + V++ + GV V + I D NDN P F+ + Y + E
Sbjct: 159 RGSEGFDREKLDYYEL-VVSACDGGVPPLCTELTVGVNILDVNDNTPAFDLSDYTTQVNE 217
Query: 799 NSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFI--------- 849
++ +G+ + +ATD D G N Y L E + F +DENTGV++ +
Sbjct: 218 SAPVGSSVFR---AEATDEDIGLNGEVSYRLEDESNQ-FKIDENTGVIETVTSPLACSRR 273
Query: 850 -GDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIEENSKV 902
G S ++ + +VA D G LS A L I + DEND+ P + ++N+ +
Sbjct: 274 CGRSSNKCSPNSCFIKIVASDKGLNALSGRAYLYIEVLDENDHBPIISFSKDNADI 329
Score = 59.7 bits (138), Expect = 6e-07
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 6/89 (6%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + + V V +LD NDN P F S+ Y + +A VG+ + + +A D D+G NG V Y
Sbjct: 186 LCTELTVGVNILDVNDNTPAFDLSD-YTTQVNESAPVGSSVFRAEATDEDIGLNGEVSYR 244
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI 527
L+ SN FKI+ NTG + SP+
Sbjct: 245 LEDESN-----QFKIDENTGVIETVTSPL 268
Score = 56.0 bits (129), Expect = 7e-06
Identities = 63/226 (27%), Positives = 100/226 (44%), Gaps = 18/226 (7%)
Query: 913 TAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNS 972
T G I++V N A D+ + E+ P+G+++ + A D D GLNG++ Y
Sbjct: 191 TVGVNILDVND-NTPAFDLSDYTTQ--VNESAPVGSSVFRAEATDEDIGLNGEVSYRLED 247
Query: 973 EVYIPPSKLSADALE-VKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNI 1029
E + +E V + R G + P S F + I A D G L+
Sbjct: 248 ESNQFKIDENTGVIETVTSPLACSRRCGRS--SNKCSPNSCF-IKIVASDKGLNALSGRA 304
Query: 1030 SVRVFVKDVNDHFPVFKKTWYNFN-----VEEAQYTRRVLGKVDATDADFGQNANLTY-F 1083
+ + V D NDH P+ + N + V+E+ + V+ V TD D G N +
Sbjct: 305 YLYIEVLDENDHBPIISFSKDNADITTASVDESADLQTVVFTVTVTDEDSGANGETSLRI 364
Query: 1084 IQPSDTDLPFEIS-PLTGV--LSVNGELDRETEDKYILTVVARDNG 1126
I+ ++ F +S P + + V LDRET +K+ LT A D+G
Sbjct: 365 IKGNEEGYFFHLSIPQYDINEIQVQKALDRETINKFNLTFEAVDHG 410
Score = 55.6 bits (128), Expect = 1e-05
Identities = 73/297 (24%), Positives = 112/297 (37%), Gaps = 23/297 (7%)
Query: 917 TIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYI 976
T+++V N+ VD + E+ G T + A D D G NG + Y S
Sbjct: 82 TVLDVND-NRPDFQVDDNKEIIAFQEDAREGRTKSIITASDPDGGNNGTVSYRIASGNEK 140
Query: 977 PPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISALDGG--NLNDNISVRVF 1034
L L + Y V G + L +SA DGG L ++V V
Sbjct: 141 GMFGLDFTGLPLILYLVKRGSEGF-----DREKLDYYELVVSACDGGVPPLCTELTVGVN 195
Query: 1035 VKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFE 1094
+ DVND+ P F + Y V E+ + + +ATD D G N ++Y ++ D F+
Sbjct: 196 ILDVNDNTPAFDLSDYTTQVNESAPVGSSVFRAEATDEDIGLNGEVSYRLE--DESNQFK 253
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAF 1154
I TGV ++ T R + +N S + Y +
Sbjct: 254 IDENTGV------IETVTSPLACSRRCGRSSNKCSPNSCFIKIVASDKGLNALSGRAYLY 307
Query: 1155 DELL-EWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
E+L E H S N + + A+++E+A + T V V D D NG
Sbjct: 308 IEVLDENDHBPIISFSKDNAD------ITTASVDESADLQTVVFTVTVTDEDSGANG 358
Score = 47.2 bits (107), Expect = 0.003
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 12/138 (8%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LF L S +G+L +D ++ FV+ + L++ + + V I +LD+NDN
Sbjct: 34 LFEL-STSGTLRTLDSIDRESIPESLVRLFVVGTPPTTLDSQVTFS---VVITVLDVNDN 89
Query: 303 LPEFEVDFYN--ISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKGAFSID--- 355
P+F+VD I+ E+ G + + A+D D G NG +Y++ + KG F +D
Sbjct: 90 RPDFQVDDNKEIIAFQEDAREGRTKSIITASDPDGGNNGTVSYRIASGNEKGMFGLDFTG 149
Query: 356 -PRSGWLTVRNQTVLDRE 372
P +L R DRE
Sbjct: 150 LPLILYLVKRGSEGFDRE 167
Score = 42.7 bits (96), Expect = 0.075
Identities = 82/336 (24%), Positives = 131/336 (38%), Gaps = 34/336 (10%)
Query: 444 NVEVTLLDANDNNPVF-VPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRT 502
+V +T+LD NDN P F V N + + +A+ G + A DPD G NG V Y +
Sbjct: 78 SVVITVLDVNDNRPDFQVDDNKEIIAFQEDAREGRTKSIITASDPDGGNNGTVSYRIASG 137
Query: 503 S-----NLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ L T I S + L V A D P ++ V +
Sbjct: 138 NEKGMFGLDFTGLPLILYLVKRGSEGFDREKLDYYELVVSACDGGVPPLCTELTVGVNIL 197
Query: 558 EVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSV--GQIRVNDAFEQNDVSYDLLHGYE 615
+V T P F + Y V + +G+SV + D +VSY L +
Sbjct: 198 DVNDNT-------PAFDLSDYTTQVNESAPVGSSVFRAEATDEDIGLNGEVSYRL---ED 247
Query: 616 EGVPFAVEERSGVI-TVVDDLSRYNR---------PMYDF-EAVALQENAN-LSIVTNAT 663
E F ++E +GVI TV L+ R P F + VA + N LS
Sbjct: 248 ESNQFKIDENTGVIETVTSPLACSRRCGRSSNKCSPNSCFIKIVASDKGLNALSGRAYLY 307
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMS--SIYGNGTGNVRFLIA 721
+ V+D ND ++ + I + + +F ++ NG ++R +
Sbjct: 308 IEVLDENDHBPIISFSKDNADITTASVDESADLQTVVFTVTVTDEDSGANGETSLRIIKG 367
Query: 722 NQQDVTDDIAIA--EDGTIFTQKPLDREKRDVYRMT 755
N++ ++I + I QK LDRE + + +T
Sbjct: 368 NEEGYFFHLSIPQYDINEIQVQKALDRETINKFNLT 403
Score = 36.7 bits (81), Expect = 4.9
Identities = 42/168 (25%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 220 AIDQDLGVGATLRYELISGN-----DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVL 274
A D+D+G+ + Y L + D +++V L + + + N+ +
Sbjct: 230 ATDEDIGLNGEVSYRLEDESNQFKIDENTGVIETVTSPLACSRRCGRSS-NKCSPNSCFI 288
Query: 275 QVQASQLNNPLKTAQARVEIELLDLNDNLP-----EFEVDFYNISIVENLPNGFSVLQVM 329
++ AS + +A + IE+LD ND+ P + D S+ E+ V V
Sbjct: 289 KIVASDKGLNALSGRAYLYIEVLDENDHBPIISFSKDNADITTASVDESADLQTVVFTVT 348
Query: 330 ATDKDQGENGEFTYQL--DDPKGAF---SIDPRSGWLTVRNQTVLDRE 372
TD+D G NGE + ++ + +G F SI P+ ++ Q LDRE
Sbjct: 349 VTDEDSGANGETSLRIIKGNEEGYFFHLSI-PQYDINEIQVQKALDRE 395
>UniRef50_Q4S1I4 Cluster: Chromosome 6 SCAF14768, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 6 SCAF14768, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 771
Score = 81.8 bits (193), Expect = 1e-13
Identities = 84/293 (28%), Positives = 133/293 (45%), Gaps = 27/293 (9%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL----DSVNGSLFLEKELDLDAEHN--LQANT 271
I A D D+G A + Y ++ + +F++ D+ +G + L K LD + + + L+
Sbjct: 225 IKAADADIGSNAEMDYRIMDSDGLGVFNVTTDEDTQDGVITLLKPLDFETKSSFSLRIEA 284
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
+ + LN + V++ + D+ D P F N+ + E+ G S+ +V A
Sbjct: 285 INRNIDTNFLNLGPFSDTTSVKVTVQDV-DEPPVFSAPLTNMVVSEDARVGTSIGKVSAY 343
Query: 332 DKDQGENGEFTYQLD---DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNP 388
D D NG Y +D D + F+ID SG + LDREA+S + + A ET P
Sbjct: 344 DPDTSNNG-IRYTIDRHTDLERFFNIDALSG--VISTAKPLDREANSVHNLSILATET-P 399
Query: 389 SVVG---TFADSQRIAKWRRQPLETNAPLEKTTYVF-PDKVGTKTENIEYYDEQLMSFVN 444
+ TF ++ + +PL P + +V PD + EN EQ+ +
Sbjct: 400 KLARRRLTFRRAEWVFGRSEEPLSQKRP--RAAHVSGPDNIPALREN----PEQIGKGIT 453
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLY 497
+ VT+LD NDN PVF YE + N G VI + AVD D +G Y
Sbjct: 454 L-VTVLDINDNAPVFAID--YETLLCENTTPGQVIQSISAVDKDEPVSGHRFY 503
Score = 66.1 bits (154), Expect = 7e-09
Identities = 46/130 (35%), Positives = 71/130 (54%), Gaps = 10/130 (7%)
Query: 744 LDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKI 802
+DRE RD Y + + A+ G + G +G VT+ + D NDNPP F H Y+ ++E+ +
Sbjct: 159 MDRETRDQYVLVIQAKDMVGQMGGLSGTTSVTVTLTDVNDNPPRFSHKNYQYTVLESLPV 218
Query: 803 GTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDV--DENT--GVVKFIGDSLDREK 857
+ + IKA DAD G+NA Y + +G +F+V DE+T GV+ + LD E
Sbjct: 219 RSVVAK---IKAADADIGSNAEMDYRIMDSDGLGVFNVTTDEDTQDGVITLL-KPLDFET 274
Query: 858 KIMYKLSLVA 867
K + L + A
Sbjct: 275 KSSFSLRIEA 284
Score = 61.7 bits (143), Expect = 2e-07
Identities = 53/188 (28%), Positives = 77/188 (40%), Gaps = 17/188 (9%)
Query: 1023 GNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTY 1082
G L+ SV V + DVND+ P F Y + V E+ R V+ K+ A DAD G NA + Y
Sbjct: 181 GGLSGTTSVTVTLTDVNDNPPRFSHKNYQYTVLESLPVRSVVAKIKAADADIGSNAEMDY 240
Query: 1083 FIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXX 1142
I SD GV +V D +T+D I + D
Sbjct: 241 RIMDSDG---------LGVFNVT--TDEDTQDGVITLLKPLDFETKSSFSLRIEAINRNI 289
Query: 1143 DVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFAN 1202
D N + ++ ++ + DE V P+ + E+A +GT++ KV A
Sbjct: 290 DTNFLNLGPFSDTTSVKVTVQDVDE------PPVFSAPLTNMVVSEDARVGTSIGKVSAY 343
Query: 1203 DTDFIGNG 1210
D D NG
Sbjct: 344 DPDTSNNG 351
Score = 60.9 bits (141), Expect = 3e-07
Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 13/178 (7%)
Query: 272 FVLQVQASQLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+VL +QA + + + V + L D+NDN P F Y +++E+LP V ++
Sbjct: 167 YVLVIQAKDMVGQMGGLSGTTSVTVTLTDVNDNPPRFSHKNYQYTVLESLPVRSVVAKIK 226
Query: 330 ATDKDQGENGEFTYQL--DDPKGAFSI----DPRSGWLTVRNQTVLDREAHSSLRMKVYA 383
A D D G N E Y++ D G F++ D + G +T+ + ++ SLR++
Sbjct: 227 AADADIGSNAEMDYRIMDSDGLGVFNVTTDEDTQDGVITLLKPLDFETKSSFSLRIEAIN 286
Query: 384 K--ETNPSVVGTFADSQRIAKWRR---QPLETNAPLEKTTYVFPDKVGTKTENIEYYD 436
+ +TN +G F+D+ + + +P +APL +VGT + YD
Sbjct: 287 RNIDTNFLNLGPFSDTTSVKVTVQDVDEPPVFSAPLTNMVVSEDARVGTSIGKVSAYD 344
Score = 60.5 bits (140), Expect = 3e-07
Identities = 50/189 (26%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 938 FLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADA-LEVKRYFVINE 996
+ + E++P+ + + K+ A D D G N ++ Y + ++ D + ++
Sbjct: 210 YTVLESLPVRSVVAKIKAADADIGSNAEMDYRIMDSDGLGVFNVTTDEDTQDGVITLLKP 269
Query: 997 RHGHVIVARSLPPESEFR-LNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVE 1055
+ SL E+ R ++ + L+ G +D SV+V V+DV D PVF N V
Sbjct: 270 LDFETKSSFSLRIEAINRNIDTNFLNLGPFSDTTSVKVTVQDV-DEPPVFSAPLTNMVVS 328
Query: 1056 EAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDK 1115
E +GKV A D D N + +D + F I L+GV+S LDRE
Sbjct: 329 EDARVGTSIGKVSAYDPDTSNNGIRYTIDRHTDLERFFNIDALSGVISTAKPLDREANSV 388
Query: 1116 YILTVVARD 1124
+ L+++A +
Sbjct: 389 HNLSILATE 397
Score = 59.7 bits (138), Expect = 6e-07
Identities = 89/366 (24%), Positives = 152/366 (41%), Gaps = 38/366 (10%)
Query: 630 TVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPIIF 686
T + ++ R R Y A + + LS T+ TV + DVND + +H +
Sbjct: 154 TALPNMDRETRDQYVLVIQAKDMVGQMGGLSGTTSVTVTLTDVNDNPP---RFSHKNYQY 210
Query: 687 HVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQ---DVTDDIAIAEDGTIFTQKP 743
V E+ ++ + I N + R + ++ +VT D +DG I KP
Sbjct: 211 TVLESLPVRSVVAKIKAADADIGSNAEMDYRIMDSDGLGVFNVTTD-EDTQDGVITLLKP 269
Query: 744 LDREKRDVYRMTVIAE--------FNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
LD E + + + + A N G S +VT+ DE PPVF
Sbjct: 270 LDFETKSSFSLRIEAINRNIDTNFLNLGPFSDTTSVKVTVQDVDE---PPVFSAPLTNMV 326
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTL--FGEGKEMFDVDENTGVVKFIGDSL 853
+ E++++GT I + A D D N + YT+ + + F++D +GV+ L
Sbjct: 327 VSEDARVGTSI---GKVSAYDPDTSNNGI-RYTIDRHTDLERFFNIDALSGVIS-TAKPL 381
Query: 854 DREKKIMYKLSLVARDTGGLS------SEAELIIMIGDE--NDNKPEFNQIEENSKVRIH 905
DRE ++ LS++A +T L+ AE + +E + +P + +
Sbjct: 382 DREANSVHNLSILATETPKLARRRLTFRRAEWVFGRSEEPLSQKRPRAAHVSGPDNIPAL 441
Query: 906 RETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPIGTTIIKLNALDLDSGLNGQ 965
RE G T++ V N A V + L+ EN G I ++A+D D ++G
Sbjct: 442 RENPEQIGKGITLVTVLDINDNA-PVFAIDYETLLCENTTPGQVIQSISAVDKDEPVSGH 500
Query: 966 IRYEFN 971
R+ F+
Sbjct: 501 -RFYFS 505
Score = 58.0 bits (134), Expect = 2e-06
Identities = 48/216 (22%), Positives = 90/216 (41%), Gaps = 4/216 (1%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L +V VTL D NDN P F N Y++++ + V +V+ K+KA D D+G N + Y
Sbjct: 183 LSGTTSVTVTLTDVNDNPPRFSHKN-YQYTVLESLPVRSVVAKIKAADADIGSNAEMDYR 241
Query: 499 LQRTSNLTITS-PFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTI 557
+ + L + + + G +++ + E + + + N +L +
Sbjct: 242 IMDSDGLGVFNVTTDEDTQDGVITLLKPLDFETKSSFSLRIEAINRNIDTNFLNLGPFSD 301
Query: 558 EVTRGTKGNKPDIPDFMGAPY-EFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDLLHGYE 615
+ D P AP V + +GTS+G++ D N + Y + +
Sbjct: 302 TTSVKVTVQDVDEPPVFSAPLTNMVVSEDARVGTSIGKVSAYDPDTSNNGIRYTIDRHTD 361
Query: 616 EGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
F ++ SGVI+ L R +++ +A +
Sbjct: 362 LERFFNIDALSGVISTAKPLDREANSVHNLSILATE 397
Score = 53.6 bits (123), Expect = 4e-05
Identities = 64/256 (25%), Positives = 107/256 (41%), Gaps = 32/256 (12%)
Query: 1108 LDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKF----YAFDEL----- 1157
+DRET D+Y+L + A+D G DVNDN P+F Y + L
Sbjct: 159 MDRETRDQYVLVIQAKDMVGQMGGLSGTTSVTVTLTDVNDNPPRFSHKNYQYTVLESLPV 218
Query: 1158 ----LEWKHPEADELSNHNFESVMM----IPVYKATIEENAPIGT-TVAKVFANDTDFIG 1208
+ K +AD SN + +M + V+ T +E+ G T+ K +T
Sbjct: 219 RSVVAKIKAADADIGSNAEMDYRIMDSDGLGVFNVTTDEDTQDGVITLLKPLDFETK--- 275
Query: 1209 NGNGLILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE 1268
+ L + ++ + + L L S T + VTV DV + PVF + + + E
Sbjct: 276 SSFSLRIEAINRNIDTNFLNLGPFSDTTSVKVTVQDV------DEPPVFSAPLTNMVVSE 329
Query: 1269 NVNAPVELVSLNLTE-HYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKD 1327
+ + ++ + N +RY I + TD+ R F ID +G + + DRE
Sbjct: 330 DARVGTSIGKVSAYDPDTSNNGIRYTI--DRHTDLERFFNIDALSGVISTAKPLDREANS 387
Query: 1328 TYEV-IVRAERQKYSR 1342
+ + I+ E K +R
Sbjct: 388 VHNLSILATETPKLAR 403
Score = 47.6 bits (108), Expect = 0.003
Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
+V+VT+ D D PVF + L + +A+VGT IGKV A DPD NG + Y + R +
Sbjct: 304 SVKVTVQDV-DEPPVF-SAPLTNMVVSEDARVGTSIGKVSAYDPDTSNNG-IRYTIDRHT 360
Query: 504 NLTITSPFKINPNTGTVSVAESPILEGR--HALFVEASDQP 542
+L F I+ +G +S A+ E H L + A++ P
Sbjct: 361 DL--ERFFNIDALSGVISTAKPLDREANSVHNLSILATETP 399
Score = 41.9 bits (94), Expect = 0.13
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 283 NPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
NP + + + +LD+NDN P F +D Y + EN G + + A DKD+ +G
Sbjct: 444 NPEQIGKGITLVTVLDINDNAPVFAID-YETLLCENTTPGQVIQSISAVDKDEPVSGHRF 502
Query: 343 YQLDDPKGA 351
Y DP A
Sbjct: 503 YFSLDPSVA 511
Score = 39.1 bits (87), Expect = 0.92
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 27/205 (13%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAF--EQNDVSYDLLHGYEEGVPFAV----EE 624
P F Y++ V ++ + + V +I+ DA ++ Y ++ GV F V +
Sbjct: 201 PRFSHKNYQYTVLESLPVRSVVAKIKAADADIGSNAEMDYRIMDSDGLGV-FNVTTDEDT 259
Query: 625 RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV--------TNATVHVVDVNDERGVL 676
+ GVIT++ L + + A+ N + + + T+ V V DV DE V
Sbjct: 260 QDGVITLLKPLDFETKSSFSLRIEAINRNIDTNFLNLGPFSDTTSVKVTVQDV-DEPPVF 318
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGN--VRFLIANQQDVTDDIAI-A 733
+ ++ ++ G +IG++ S Y T N +R+ I D+ I A
Sbjct: 319 SAPLTNMVVS--EDARVGTSIGKV------SAYDPDTSNNGIRYTIDRHTDLERFFNIDA 370
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIA 758
G I T KPLDRE V+ ++++A
Sbjct: 371 LSGVISTAKPLDREANSVHNLSILA 395
>UniRef50_UPI0000F20971 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
protein, partial - Danio rerio
Length = 1102
Score = 81.4 bits (192), Expect = 2e-13
Identities = 65/179 (36%), Positives = 89/179 (49%), Gaps = 16/179 (8%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G + LDREK Y +T IA++ G I+ I + I +ED+NDN P+F +
Sbjct: 34 ENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENI-MLKIKVEDQNDNFPIFREQS-- 90
Query: 794 GFIMENSKIGTEIKMDNIIKATDAD-EGT-NALFMYTLF----GEGKEMFDVDENTGVVK 847
G + E+SKIGT + I+ATDAD EGT N+ Y++ E MF +D TG V
Sbjct: 91 GSVKESSKIGTPVMQ---IRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVY 147
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSS----EAELIIMIGDENDNKPEFNQIEENSKV 902
LDRE+ Y L + D G S + I I D NDN P + E + V
Sbjct: 148 VKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSV 206
Score = 66.1 bits (154), Expect = 7e-09
Identities = 52/169 (30%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISAL----DGGNLNDNISVRVFVKDVNDHFPVFKK 1047
FVIN +G+V V L E N++ + +G +NI +++ V+D ND+FP+F++
Sbjct: 29 FVINPENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDNFPIFRE 88
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQ--NANLTYFI---QPSDTDLPFEISPLTGVL 1102
+ +V+E+ + ++ ATDAD N+ + Y I P+++ F I TG +
Sbjct: 89 --QSGSVKESSKIGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNV 146
Query: 1103 SVNGE-LDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSP 1149
V + LDRE DKY L V D +G D+NDN P
Sbjct: 147 YVKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVP 195
Score = 48.4 bits (110), Expect = 0.002
Identities = 70/262 (26%), Positives = 106/262 (40%), Gaps = 27/262 (10%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT-NATVHVVDVNDERGVLLK 678
F + +G + V L R Y+ +A N +++ + V D ND + +
Sbjct: 29 FVINPENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDNFPIFRE 88
Query: 679 GAHSPIIFHVKENSA-GAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED-- 735
+ S VKE+S G + QI T+ G + + I Q + D
Sbjct: 89 QSGS-----VKESSKIGTPVMQIRATDADE-EGTINSKIAYSIIKQSPAESGNMFSIDRA 142
Query: 736 -GTIFT-QKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNPPVFEHATY 792
G ++ +K LDRE+ D Y + V G SG G V I I D NDN P E Y
Sbjct: 143 TGNVYVKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEY 202
Query: 793 EGFIMEN--SKIGTEIK-MDNIIKATDADEGTNALFMYTLF-GEGKEMFDVD----ENTG 844
G + E + IK D +K TD N L ++ + G +F ++ N G
Sbjct: 203 SGSVDEGVVDVVVMRIKAQDKDLKFTD-----NWLAVFDILKGNEDNLFSIETDPKTNEG 257
Query: 845 VVKFIGDSLDREKKIMYKLSLV 866
++K I +D EK L+LV
Sbjct: 258 ILKLI-KPVDFEKVKELDLNLV 278
Score = 48.0 bits (109), Expect = 0.002
Identities = 45/183 (24%), Positives = 90/183 (49%), Gaps = 16/183 (8%)
Query: 222 DQDLGVGATLRYELISGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
D++ + + + Y +I + + +FS+D G++++++++ LD E + + + L VQ
Sbjct: 112 DEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKI-LDRERH---DKYTLIVQG 167
Query: 279 SQLN-NPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
++ +P T V I +LD+NDN+P E + Y+ S+ E + + V+++ A DKD
Sbjct: 168 VDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSVDEGVVD-VVVMRIKAQDKDLK 226
Query: 337 ENGEFTYQLDDPKG----AFSI--DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
+ D KG FSI DP++ ++ +D E L + + P +
Sbjct: 227 FTDNWLAVFDILKGNEDNLFSIETDPKTNEGILKLIKPVDFEKVKELDLNLVISNVAPFI 286
Query: 391 VGT 393
G+
Sbjct: 287 NGS 289
Score = 47.2 bits (107), Expect = 0.003
Identities = 69/266 (25%), Positives = 116/266 (43%), Gaps = 31/266 (11%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
K N +E +M + VE D NDN P+F + S+K ++K+GT + +++A D
Sbjct: 59 KYRNGSIAEENIMLKIKVE----DQNDNFPIFREQS---GSVKESSKIGTPVMQIRATDA 111
Query: 488 DLGQ--NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH---ALFVEASDQP 542
D N + Y + + S + F I+ TG V V E + RH L V+ D
Sbjct: 112 DEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKILDRERHDKYTLIVQGVDMD 171
Query: 543 ANPSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND--- 599
+PS V I + ++P Y V V + V +I+ D
Sbjct: 172 GHPSGNT-GTGTVHINIL----DINDNVPTLEKEEYSGSVDEGV-VDVVVMRIKAQDKDL 225
Query: 600 AFEQNDVS-YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAV-ALQEN---A 654
F N ++ +D+L G E+ + F++E + + + +P+ DFE V L N +
Sbjct: 226 KFTDNWLAVFDILKGNEDNL-FSIETDP---KTNEGILKLIKPV-DFEKVKELDLNLVIS 280
Query: 655 NLSIVTNATVHVVDVNDERGVLLKGA 680
N++ N + +DVN ++G GA
Sbjct: 281 NVAPFINGSALELDVNLDKGGAGAGA 306
Score = 40.3 bits (90), Expect = 0.40
Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 15/146 (10%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LF ++ NG + + LD + + +++ L A N + ++I++ D NDN
Sbjct: 28 LFVINPENGYVKVTGLLDRE-----KTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDN 82
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQLDDPKGA-----FSID 355
P F + S+ E+ G V+Q+ ATD D+ N + Y + A FSID
Sbjct: 83 FPIFREQ--SGSVKESSKIGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSID 140
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKV 381
+G + V+ + +LDRE H + V
Sbjct: 141 RATGNVYVK-EKILDRERHDKYTLIV 165
>UniRef50_UPI00015A74B2 Cluster: UPI00015A74B2 related cluster; n=1;
Danio rerio|Rep: UPI00015A74B2 UniRef100 entry - Danio
rerio
Length = 747
Score = 81.4 bits (192), Expect = 2e-13
Identities = 65/179 (36%), Positives = 89/179 (49%), Gaps = 16/179 (8%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E+G + LDREK Y +T IA++ G I+ I + I +ED+NDN P+F +
Sbjct: 62 ENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENI-MLKIKVEDQNDNFPIFREQS-- 118
Query: 794 GFIMENSKIGTEIKMDNIIKATDAD-EGT-NALFMYTLF----GEGKEMFDVDENTGVVK 847
G + E+SKIGT + I+ATDAD EGT N+ Y++ E MF +D TG V
Sbjct: 119 GSVKESSKIGTPVMQ---IRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVY 175
Query: 848 FIGDSLDREKKIMYKLSLVARDTGGLSS----EAELIIMIGDENDNKPEFNQIEENSKV 902
LDRE+ Y L + D G S + I I D NDN P + E + V
Sbjct: 176 VKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSV 234
Score = 66.1 bits (154), Expect = 7e-09
Identities = 52/169 (30%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 992 FVINERHGHVIVARSLPPESEFRLNISAL----DGGNLNDNISVRVFVKDVNDHFPVFKK 1047
FVIN +G+V V L E N++ + +G +NI +++ V+D ND+FP+F++
Sbjct: 57 FVINPENGYVKVTGLLDREKTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDNFPIFRE 116
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQ--NANLTYFI---QPSDTDLPFEISPLTGVL 1102
+ +V+E+ + ++ ATDAD N+ + Y I P+++ F I TG +
Sbjct: 117 --QSGSVKESSKIGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNV 174
Query: 1103 SVNGE-LDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSP 1149
V + LDRE DKY L V D +G D+NDN P
Sbjct: 175 YVKEKILDRERHDKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVP 223
Score = 49.2 bits (112), Expect = 9e-04
Identities = 79/294 (26%), Positives = 119/294 (40%), Gaps = 32/294 (10%)
Query: 592 VGQIRVNDAFEQNDVSYDLL-HGYEEGVP---FAVEERSGVITVVDDLSRYNRPMYDFEA 647
V +IR + V Y L HG + +P F + +G + V L R Y+
Sbjct: 26 VAKIRSDKDINWQVVEYGLTGHGANK-LPYNLFVINPENGYVKVTGLLDREKTSSYNLTG 84
Query: 648 VALQENANLSIVT-NATVHVVDVNDERGVLLKGAHSPIIFHVKENSA-GAAIGQIFHTNM 705
+A N +++ + V D ND + + + S VKE+S G + QI T+
Sbjct: 85 IAKYRNGSIAEENIMLKIKVEDQNDNFPIFREQSGS-----VKESSKIGTPVMQIRATDA 139
Query: 706 SSIYGNGTGNVRFLIANQQDVTDDIAIAED---GTIFT-QKPLDREKRDVYRMTVIAEFN 761
G + + I Q + D G ++ +K LDRE+ D Y + V
Sbjct: 140 DE-EGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKILDRERHDKYTLIVQGVDM 198
Query: 762 KGVISG-AGIYQVTIYIEDENDNPPVFEHATYEGFIMEN--SKIGTEIK-MDNIIKATDA 817
G SG G V I I D NDN P E Y G + E + IK D +K TD
Sbjct: 199 DGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSVDEGVVDVVVMRIKAQDKDLKFTD- 257
Query: 818 DEGTNALFMYTLF-GEGKEMFDVD----ENTGVVKFIGDSLDREKKIMYKLSLV 866
N L ++ + G +F ++ N G++K I +D EK L+LV
Sbjct: 258 ----NWLAVFDILKGNEDNLFSIETDPKTNEGILKLI-KPVDFEKVKELDLNLV 306
Score = 47.6 bits (108), Expect = 0.003
Identities = 45/182 (24%), Positives = 89/182 (48%), Gaps = 16/182 (8%)
Query: 222 DQDLGVGATLRYELISGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQA 278
D++ + + + Y +I + + +FS+D G++++++++ LD E + + + L VQ
Sbjct: 140 DEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKI-LDRERH---DKYTLIVQG 195
Query: 279 SQLN-NPL-KTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG 336
++ +P T V I +LD+NDN+P E + Y+ S+ E + + V+++ A DKD
Sbjct: 196 VDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSGSVDEGVVD-VVVMRIKAQDKDLK 254
Query: 337 ENGEFTYQLDDPKG----AFSI--DPRSGWLTVRNQTVLDREAHSSLRMKVYAKETNPSV 390
+ D KG FSI DP++ ++ +D E L + + P +
Sbjct: 255 FTDNWLAVFDILKGNEDNLFSIETDPKTNEGILKLIKPVDFEKVKELDLNLVISNVAPFI 314
Query: 391 VG 392
G
Sbjct: 315 NG 316
Score = 46.0 bits (104), Expect = 0.008
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 12/124 (9%)
Query: 428 KTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDP 487
K N +E +M + VE D NDN P+F + S+K ++K+GT + +++A D
Sbjct: 87 KYRNGSIAEENIMLKIKVE----DQNDNFPIFREQS---GSVKESSKIGTPVMQIRATDA 139
Query: 488 DLGQ--NGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRH---ALFVEASDQP 542
D N + Y + + S + F I+ TG V V E + RH L V+ D
Sbjct: 140 DEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKILDRERHDKYTLIVQGVDMD 199
Query: 543 ANPS 546
+PS
Sbjct: 200 GHPS 203
Score = 44.8 bits (101), Expect = 0.018
Identities = 77/343 (22%), Positives = 136/343 (39%), Gaps = 34/343 (9%)
Query: 588 IGTSVGQIRVNDAFEQNDVSYDLLHGY------EEGVPFAVEERSGVITVVDD-LSRYNR 640
IGT V QIR DA E+ ++ + + E G F+++ +G + V + L R
Sbjct: 127 IGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSIDRATGNVYVKEKILDRERH 186
Query: 641 PMYDFEAVALQENANLSIVT-NATVH--VVDVNDERGVLLKGAHSPIIFHVKENSAGAAI 697
Y + + + S T TVH ++D+ND L K +S V E +
Sbjct: 187 DKYTLIVQGVDMDGHPSGNTGTGTVHINILDINDNVPTLEKEEYSG---SVDEGVVDVVV 243
Query: 698 GQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---AEDGTIFTQKPLDREKRDVYRM 754
+I + + + V ++ +D I +G + KP+D EK +
Sbjct: 244 MRIKAQDKDLKFTDNWLAVFDILKGNEDNLFSIETDPKTNEGILKLIKPVDFEKVKELDL 303
Query: 755 TV----IAEFNKGVISGAGI-YQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMD 809
+ +A F G AG Y V I + + D P F + + + E+ + +
Sbjct: 304 NLVISNVAPFINGNKKPAGKGYPVKISVNNLPDGPG-FSPSVKDFPVSEDPNEDFPVVL- 361
Query: 810 NIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMY------KL 863
A D D G A Y + +DE T +K + + DRE K + K+
Sbjct: 362 GTFAALDGDTGEPATIKYAKGHDPDNWITIDEETAEIK-LTKAPDRESKFLVNGTYFAKI 420
Query: 864 SLVARDTGGLSSEAELIIMIGDENDNKPE----FNQIEENSKV 902
+ +D ++ + + + D ND+ P ++Q +N+KV
Sbjct: 421 ICMTQDVPAKTATGTIALKVEDTNDHCPTLTSCYHQTCDNNKV 463
Score = 40.3 bits (90), Expect = 0.40
Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 15/146 (10%)
Query: 243 LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDN 302
LF ++ NG + + LD + + +++ L A N + ++I++ D NDN
Sbjct: 56 LFVINPENGYVKVTGLLDRE-----KTSSYNLTGIAKYRNGSIAEENIMLKIKVEDQNDN 110
Query: 303 LPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQLDDPKGA-----FSID 355
P F + S+ E+ G V+Q+ ATD D+ N + Y + A FSID
Sbjct: 111 FPIFREQ--SGSVKESSKIGTPVMQIRATDADEEGTINSKIAYSIIKQSPAESGNMFSID 168
Query: 356 PRSGWLTVRNQTVLDREAHSSLRMKV 381
+G + V+ + +LDRE H + V
Sbjct: 169 RATGNVYVK-EKILDRERHDKYTLIV 193
>UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14607, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 684
Score = 81.4 bits (192), Expect = 2e-13
Identities = 124/503 (24%), Positives = 216/503 (42%), Gaps = 73/503 (14%)
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVV 667
+L G G FA+ E +G I + L R + Y A + + + L + + V
Sbjct: 176 ILTGEGAGTIFAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDEPLEPPSEFIIKVQ 235
Query: 668 DVNDERGVLLKGA-HSPI-----IFHVKE-NSAGAAIGQIFHTNMSS-IYGNGTGNVRFL 719
D+ND ++ HS + + V+ +++G + ++ T+ +YGN V +
Sbjct: 236 DINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSI 295
Query: 720 IANQQDVTDDIAIAEDGTI-FTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYI 777
+ Q + D TI + +DRE R+ Y + + A+ G + G +G VTI +
Sbjct: 296 LEGQPYFSID---PNSATIKVALQGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITL 352
Query: 778 EDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEM 836
D NDNPP F YE I E+ G KM +KA D D G N+ Y + G+ + +
Sbjct: 353 TDINDNPPKFSKNLYEFVIPEDLPTG---KMGGKVKANDRDTGENSKSTYGIVEGDDQGV 409
Query: 837 FDV--DENT--GVVKFIGDSLDREKKIMYKLSLVARD------TGGLSSEAELIIMIGDE 886
F++ D T G+++ + LD E K Y L + A + +GG + + + ++
Sbjct: 410 FEIVTDSQTQEGILR-LKKPLDYESKRAYTLKVEATNIRSEPGSGGPFKDTATVKIAVED 468
Query: 887 NDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIPENIPI 946
+D P F+ + ++ ++ +N G + A D D G + PE
Sbjct: 469 SDEPPVFS--KPIYQLEVNENAPINTVIG---------SVMARDPDSTGSQ-VSPET--- 513
Query: 947 GTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV-----------IN 995
+ I+K L GQ+R+ E P L+A + + RYF+ IN
Sbjct: 514 -SAILK---------LLGQVRWFGTQETDSPVGVLNASSQQGFRYFIDRHTDLERQFNIN 563
Query: 996 ERHGHVIVARSLPPESEF--RLNISALDGGNLNDNIS---VRVFVKDVNDHFPVFKKTWY 1050
G + +A+ L E++ + ++A + N + IS V + V D ND+ P F +
Sbjct: 564 VDDGKITLAKPLDRETDMWHNITVTATEVRN-HSQISRAIVAIRVMDYNDNAPEFATEYE 622
Query: 1051 NFNVEEAQYTRRVLGKVDATDAD 1073
F E + +V+ + A D D
Sbjct: 623 TFLCENGK-PGQVIQTISAVDKD 644
Score = 75.8 bits (178), Expect = 9e-12
Identities = 65/229 (28%), Positives = 110/229 (48%), Gaps = 27/229 (11%)
Query: 685 IFHVKENSAGAAIGQI-FHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAE-DGTIFTQK 742
+F N G G HT++ G ++++++ + T AI E G I K
Sbjct: 145 VFEELSNQGGHYFGYCQLHTDLDV----GGKSIKYILTGEGAGTI-FAINELTGDIHAMK 199
Query: 743 PLDREKRDVYRMT---VIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMEN 799
LDRE++ Y +T + A+ ++ + + + I ++D NDNPP F A Y + E
Sbjct: 200 RLDREEKAEYTLTAQVINADTDEPLEPPS---EFIIKVQDINDNPPQFIEAPYHSSVPEM 256
Query: 800 SKIGTEIKMD------NIIKATDADE---GTNALFMYTLFGEGKEMFDVDENTGVVKFIG 850
S +G + + ATDAD+ G +A +Y++ EG+ F +D N+ +K
Sbjct: 257 SAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSIL-EGQPYFSIDPNSATIKVAL 315
Query: 851 DSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
+DRE + Y + + A+D GGLS + I + D NDN P+F++
Sbjct: 316 QGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITLTDINDNPPKFSK 364
Score = 64.5 bits (150), Expect = 2e-08
Identities = 54/160 (33%), Positives = 78/160 (48%), Gaps = 11/160 (6%)
Query: 974 VYIPPSKLSADALEVKRYFVINERHGHVIVA-RSLPPE--SEFRLNISALD-GGN---LN 1026
VY +KL LE + YF I+ + VA + + E E+ + I A D GG+ L+
Sbjct: 284 VYGNSAKLVYSILEGQPYFSIDPNSATIKVALQGMDREMREEYLVVIQAKDMGGHMGGLS 343
Query: 1027 DNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQP 1086
+V + + D+ND+ P F K Y F + E T ++ GKV A D D G+N+ TY I
Sbjct: 344 GTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYGIVE 403
Query: 1087 SDTDLPFEI----SPLTGVLSVNGELDRETEDKYILTVVA 1122
D FEI G+L + LD E++ Y L V A
Sbjct: 404 GDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEA 443
Score = 63.7 bits (148), Expect = 4e-08
Identities = 54/189 (28%), Positives = 90/189 (47%), Gaps = 14/189 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y ++ G + FS+D + ++ + + +D E +++ +QA
Sbjct: 280 ADDPVYGNSAKLVYSILEG--QPYFSIDPNSATIKVALQ-GMDRE---MREEYLVVIQAK 333
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + + V I L D+NDN P+F + Y I E+LP G +V A D+D GE
Sbjct: 334 DMGGHMGGLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGE 393
Query: 338 NGEFTYQL--DDPKGAFSI--DPRSGWLTVRNQTVLDREAHSSLRMKVYAK--ETNPSVV 391
N + TY + D +G F I D ++ +R + LD E+ + +KV A + P
Sbjct: 394 NSKSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSG 453
Query: 392 GTFADSQRI 400
G F D+ +
Sbjct: 454 GPFKDTATV 462
Score = 54.8 bits (126), Expect = 2e-05
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 18/176 (10%)
Query: 222 DQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQL 281
D D+G G +++Y L +F+++ + G + K LD + + T QV +
Sbjct: 165 DLDVG-GKSIKYILTGEGAGTIFAINELTGDIHAMKRLDREEKAEY---TLTAQVINADT 220
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENL---------PNGFSVLQVMATD 332
+ PL+ + I++ D+NDN P+F Y+ S+ E +G V +V ATD
Sbjct: 221 DEPLEPPSEFI-IKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATD 279
Query: 333 KDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D G + + Y + + + FSIDP S + V Q +DRE + + AK+
Sbjct: 280 ADDPVYGNSAKLVYSILEGQPYFSIDPNSATIKVALQG-MDREMREEYLVVIQAKD 334
Score = 53.6 bits (123), Expect = 4e-05
Identities = 44/164 (26%), Positives = 68/164 (41%), Gaps = 7/164 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V +TL D NDN P F NLYEF + + G + GKVKA D D G+N Y
Sbjct: 342 LSGTTTVTITLTDINDNPPKF-SKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYG 400
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPI-LEGRHA--LFVEASDQPANPSERRYSLAVV 555
+ + + + + + P+ E + A L VEA++ + P
Sbjct: 401 IVEGDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGPFKDTA 460
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVND 599
T+++ + + P F Y+ V N I T +G + D
Sbjct: 461 TVKI---AVEDSDEPPVFSKPIYQLEVNENAPINTVIGSVMARD 501
Score = 53.2 bits (122), Expect = 5e-05
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 27/258 (10%)
Query: 571 PDFMGAPYEFWVG--SNVGI-------GTSVGQIRVNDAFEQ-NDVSYDLLHGYEEGVP- 619
P F+ APY V S VG GT V ++ DA + S L++ EG P
Sbjct: 242 PQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSILEGQPY 301
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN------ANLSIVTNATVHVVDVNDER 673
F+++ S I V L +R M + V +Q LS T T+ + D+ND
Sbjct: 302 FSIDPNSATIKVA--LQGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITLTDINDNP 359
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIA 733
K + F + E+ +G N N + + Q V + + +
Sbjct: 360 PKFSKNLYE---FVIPEDLPTGKMGGKVKANDRDTGENSKSTYGIVEGDDQGVFEIVTDS 416
Query: 734 E--DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIE---DENDNPPVFE 788
+ +G + +KPLD E + Y + V A + G ++ T ++ +++D PPVF
Sbjct: 417 QTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGPFKDTATVKIAVEDSDEPPVFS 476
Query: 789 HATYEGFIMENSKIGTEI 806
Y+ + EN+ I T I
Sbjct: 477 KPIYQLEVNENAPINTVI 494
Score = 52.8 bits (121), Expect = 7e-05
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 19/178 (10%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALDGGN---LNDNISVRVFVKDVNDHFPVFK 1046
F INE G + + L E +E+ L ++ L + V+D+ND+ P F
Sbjct: 186 FAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDEPLEPPSEFIIKVQDINDNPPQFI 245
Query: 1047 KTWYNFNVEEAQYTRRV---------LGKVDATDAD---FGQNANLTYFIQPSDTDLPFE 1094
+ Y+ +V E V + +V ATDAD +G +A L Y I +
Sbjct: 246 EAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSILEGQPYFSID 305
Query: 1095 ISPLTGVLSVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
+ T +++ G +DRE ++Y++ + A+D G D+NDN PKF
Sbjct: 306 PNSATIKVALQG-MDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITLTDINDNPPKF 362
Score = 48.4 bits (110), Expect = 0.002
Identities = 47/140 (33%), Positives = 60/140 (42%), Gaps = 11/140 (7%)
Query: 717 RFLIANQQDVTDDIAI-AEDGTIFTQKPLDREKRDVYRMTVIAE--FNKGVISGAGIYQV 773
R+ I D+ I +DG I KPLDRE + +TV A N IS A V
Sbjct: 547 RYFIDRHTDLERQFNINVDDGKITLAKPLDRETDMWHNITVTATEVRNHSQISRA---IV 603
Query: 774 TIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGE- 832
I + D NDN P F YE F+ EN K G I+ + + D +G F Y L E
Sbjct: 604 AIRVMDYNDNAPEFA-TEYETFLCENGKPGQVIQTISAVDKDDPIQG--HYFNYRLAPEM 660
Query: 833 -GKEMFDVDENTGVVKFIGD 851
F + N G K I +
Sbjct: 661 LNNPNFTIKNNQGGYKHINE 680
Score = 47.2 bits (107), Expect = 0.003
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 244 FSLDSVNGSLFLEKELDLDAE--HNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
F+++ +G + L K LD + + HN+ V A+++ N + ++A V I ++D ND
Sbjct: 560 FNINVDDGKITLAKPLDRETDMWHNIT-------VTATEVRNHSQISRAIVAIRVMDYND 612
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGE-FTYQL 345
N PEF + Y + EN G + + A DKD G F Y+L
Sbjct: 613 NAPEFATE-YETFLCENGKPGQVIQTISAVDKDDPIQGHYFNYRL 656
Score = 42.3 bits (95), Expect = 0.099
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 7/122 (5%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL----DSVNGSLFLEKELDLDAEHNLQANTFV 273
+ A D+D G + Y ++ G+D+ +F + + G L L+K LD +++
Sbjct: 384 VKANDRDTGENSKSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEA 443
Query: 274 LQVQASQ-LNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATD 332
+++ P K A V+I + D +D P F Y + + EN P + VMA D
Sbjct: 444 TNIRSEPGSGGPFKDT-ATVKIAVED-SDEPPVFSKPIYQLEVNENAPINTVIGSVMARD 501
Query: 333 KD 334
D
Sbjct: 502 PD 503
Score = 37.1 bits (82), Expect = 3.7
Identities = 12/29 (41%), Positives = 21/29 (72%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ ++D+NDN P F++ PYH +V E++ G
Sbjct: 232 IKVQDINDNPPQFIEAPYHSSVPEMSAVG 260
Score = 35.9 bits (79), Expect = 8.6
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXX 1129
TD D G ++ Y + F I+ LTG + LDRE + +Y LT +
Sbjct: 164 TDLDVG-GKSIKYILTGEGAGTIFAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDE 222
Query: 1130 XXXXXXXXXXXXXDVNDNSPKF 1151
D+NDN P+F
Sbjct: 223 PLEPPSEFIIKVQDINDNPPQF 244
>UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15;
Tetrapoda|Rep: Cadherin-19 precursor - Homo sapiens
(Human)
Length = 772
Score = 81.4 bits (192), Expect = 2e-13
Identities = 58/191 (30%), Positives = 88/191 (46%), Gaps = 10/191 (5%)
Query: 711 NGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVY--RMTVIAEFNKGVISGA 768
NG + ++ + + I G I+ + LDRE+R +Y R VI +
Sbjct: 72 NGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPE 131
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
+ I + D NDN P F YE + E S GT + A D G NA +Y+
Sbjct: 132 S--EFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYS 189
Query: 829 LFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD----TGGLSSEAELIIMIG 884
L +G+ F V+ TGV++ I +DRE + Y + + A+D G LS ++I +
Sbjct: 190 LL-QGQPYFSVEPTTGVIR-ISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLS 247
Query: 885 DENDNKPEFNQ 895
D NDNKP F +
Sbjct: 248 DVNDNKPIFKE 258
Score = 73.3 bits (172), Expect = 5e-11
Identities = 65/254 (25%), Positives = 106/254 (41%), Gaps = 11/254 (4%)
Query: 592 VGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ 651
+GQ+R + N Y LL G G F ++ER+G I + L R R +Y A +
Sbjct: 63 IGQLRSDLDNGNNSFQYKLL-GAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVID 121
Query: 652 ENANLSIVTNA--TVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY 709
++ + + V D+ND L + I+ + G + Q+ ++
Sbjct: 122 IATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPE--GTLVIQVTASDADD-- 177
Query: 710 GNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-A 768
+ N R L + Q G I +DRE +D Y + + A+ G +
Sbjct: 178 PSSGNNARLLYSLLQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALS 237
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYT 828
G V I + D NDN P+F+ + Y + E++ GT I I A D D G NA Y+
Sbjct: 238 GTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSI---GTIMAYDNDIGENAEMDYS 294
Query: 829 LFGEGKEMFDVDEN 842
+ + + FD+ N
Sbjct: 295 IEEDDSQTFDIITN 308
Score = 72.5 bits (170), Expect = 8e-11
Identities = 101/466 (21%), Positives = 195/466 (41%), Gaps = 48/466 (10%)
Query: 447 VTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVD---PDLGQNGMVLYDLQRTS 503
+ + D NDN P F+ YE + + GT++ +V A D P G N +LY L +
Sbjct: 136 IKVSDINDNEPKFLDEP-YEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQ 194
Query: 504 NLTITSPFKINPNTGTVSVAESPI--LEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
F + P TG + ++ L+ + + ++A D P + +V+ I+++
Sbjct: 195 PY-----FSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVL-IKLS- 247
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRV--NDAFEQNDVSYDLLHGYEEGVP 619
NKP + + Y V + GTS+G I ND E ++ Y + +
Sbjct: 248 DVNDNKPIFKESL---YRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFD 304
Query: 620 FAV--EERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIV---TNATVHVVDVN---- 670
E + G++ + + ++ Y A + ++ T A+ + +
Sbjct: 305 IITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDV 364
Query: 671 DERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
DE + L + +F +E G+ +G + T+ N +R+ I +
Sbjct: 365 DEPPLFLLPYYVFEVF--EETPQGSFVGVVSATDPD----NRKSPIRYSITRSKVFN--- 415
Query: 731 AIAEDGTIFTQKPLDREKRDVYRMTVIA--EFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
I ++GTI T LDRE Y +++ A ++N IS +Y + + + ND+ P F
Sbjct: 416 -INDNGTITTSNSLDREISAWYNLSITATEKYNIEQISSIPLY---VQVLNINDHAPEFS 471
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMF---DVDENTGV 845
YE ++ EN+ G I+ + + ++ E + F ++ F D +NT V
Sbjct: 472 Q-YYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAV 530
Query: 846 VKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDN 889
+ + +++ ++ +S++ D G L+S L I + D D+
Sbjct: 531 ILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGDS 576
Score = 70.5 bits (165), Expect = 3e-10
Identities = 95/377 (25%), Positives = 157/377 (41%), Gaps = 42/377 (11%)
Query: 992 FVINERHGHVIVARSLPPE--SEFRLNISALD---GGNLNDNISVRVFVKDVNDHFPVFK 1046
F+I+ER G + + L E S + L +D G + + V D+ND+ P F
Sbjct: 90 FIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFL 149
Query: 1047 KTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDTDLPFEISPLTGVLS 1103
Y V E ++ +V A+DAD G NA L Y + F + P TGV+
Sbjct: 150 DEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPY--FSVEPTTGVIR 207
Query: 1104 VNGELDRETEDKYILTVVARDN-GXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKH 1162
++ ++DRE +D+Y + + A+D G DVNDN P F + L
Sbjct: 208 ISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFK--ESLYRLTV 265
Query: 1163 PEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG----LILYSL 1218
E+ S+ I Y I ENA + ++ + + D I N +IL
Sbjct: 266 SESAPTGT----SIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQEGIVILKKK 321
Query: 1219 PQRKNQQNLGL---------PSLSSTAILMVTVADVPDEVE-MSDKPVFISRYYELEIEE 1268
++Q + G+ P + + +VE + + P+F+ YY E+ E
Sbjct: 322 VDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFE 381
Query: 1269 NV--NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVK 1326
+ V +VS ++ ++ +RY I + F I+ NGT+ S DRE+
Sbjct: 382 ETPQGSFVGVVSATDPDNRKS-PIRYSITRS------KVFNIND-NGTITTSNSLDREIS 433
Query: 1327 DTYEVIVRAERQKYSRE 1343
Y + + A +KY+ E
Sbjct: 434 AWYNLSITA-TEKYNIE 449
Score = 68.5 bits (160), Expect = 1e-09
Identities = 86/345 (24%), Positives = 154/345 (44%), Gaps = 32/345 (9%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFE-QNDVSYDLLHGYEEGVP-FAVEERSGV 628
P F+ PYE V GT V Q+ +DA + + + LL+ +G P F+VE +GV
Sbjct: 146 PKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGV 205
Query: 629 ITVVDDLSRYNRPMYDFEAVA---LQENANLSIVTNATVHVVDVNDERGVLLKGAHSPII 685
I + + R + Y A + + LS T+ + + DVND + + + +
Sbjct: 206 IRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYR--- 262
Query: 686 FHVKENS-AGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAI---AEDGTIFTQ 741
V E++ G +IG I + + I N + + I T DI ++G + +
Sbjct: 263 LTVSESAPTGTSIGTIMAYD-NDIGEN--AEMDYSIEEDDSQTFDIITNHETQEGIVILK 319
Query: 742 KPLDREKRDVYRMTV------IAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGF 795
K +D E ++ Y + + E + A + I +ED D PP+F Y
Sbjct: 320 KKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDV-DEPPLFLLPYYVFE 378
Query: 796 IMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDR 855
+ E + G+ + ++ ATD D + + Y++ ++F++++N + +SLDR
Sbjct: 379 VFEETPQGSFV---GVVSATDPDNRKSPI-RYSI--TRSKVFNINDNGTIT--TSNSLDR 430
Query: 856 EKKIMYKLSLVARDTGGLS--SEAELIIMIGDENDNKPEFNQIEE 898
E Y LS+ A + + S L + + + ND+ PEF+Q E
Sbjct: 431 EISAWYNLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYE 475
Score = 68.1 bits (159), Expect = 2e-09
Identities = 47/168 (27%), Positives = 80/168 (47%), Gaps = 12/168 (7%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A L Y L+ G + FS++ G + + ++D + LQ +V+
Sbjct: 175 ADDPSSGNNARLLYSLLQG--QPYFSVEPTTGVIRISSKMDRE----LQDEYWVIIQAKD 228
Query: 280 QLNNP-LKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGEN 338
+ P + V I+L D+NDN P F+ Y +++ E+ P G S+ +MA D D GEN
Sbjct: 229 MIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGEN 288
Query: 339 GEFTYQL-DDPKGAFSI----DPRSGWLTVRNQTVLDREAHSSLRMKV 381
E Y + +D F I + + G + ++ + + + H +R KV
Sbjct: 289 AEMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKV 336
Score = 66.5 bits (155), Expect = 5e-09
Identities = 57/215 (26%), Positives = 101/215 (46%), Gaps = 31/215 (14%)
Query: 921 VKPKNKFALDVDQLG---PLFL-------IPENIPIGTTIIKLNALDLDSGLNGQIRYEF 970
V+P+++F + V + P FL +PE P GT +I++ A D D +G
Sbjct: 128 VEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGN----- 182
Query: 971 NSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE--SEFRLNISALD----GGN 1024
++L L+ + YF + G + ++ + E E+ + I A D G
Sbjct: 183 -------NARLLYSLLQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGA 235
Query: 1025 LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
L+ SV + + DVND+ P+FK++ Y V E+ T +G + A D D G+NA + Y I
Sbjct: 236 LSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSI 295
Query: 1085 QPSDT---DLPFEISPLTGVLSVNGELDRETEDKY 1116
+ D+ D+ G++ + ++D E ++ Y
Sbjct: 296 EEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHY 330
Score = 60.5 bits (140), Expect = 3e-07
Identities = 40/159 (25%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Query: 230 TLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQ 289
+ +Y+L+ F +D G ++ ++LD + V+ + + P +
Sbjct: 76 SFQYKLLGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEP----E 131
Query: 290 ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKD---QGENGEFTYQLD 346
+ I++ D+NDN P+F + Y + E P G V+QV A+D D G N Y L
Sbjct: 132 SEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLL 191
Query: 347 DPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
+ FS++P +G +R + +DRE + + AK+
Sbjct: 192 QGQPYFSVEPTTG--VIRISSKMDRELQDEYWVIIQAKD 228
Score = 53.6 bits (123), Expect = 4e-05
Identities = 53/237 (22%), Positives = 99/237 (41%), Gaps = 11/237 (4%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L +V + L D NDN P+F S LY ++ +A GT IG + A D D+G+N + Y
Sbjct: 236 LSGTTSVLIKLSDVNDNKPIFKES-LYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYS 294
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSER--RYSLAVVT 556
++ + T G V + + E ++ + A + + E+ +Y T
Sbjct: 295 IEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEAST 354
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEE 616
+ + + + P F+ Y F V G+ VG + D + + +
Sbjct: 355 TFIKIQVE-DVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNRKS---PIRYSITR 410
Query: 617 GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNAT--VHVVDVND 671
F + + +G IT + L R Y+ ++ E N+ +++ V V+++ND
Sbjct: 411 SKVFNIND-NGTITTSNSLDREISAWYNL-SITATEKYNIEQISSIPLYVQVLNIND 465
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/83 (39%), Positives = 46/83 (55%), Gaps = 6/83 (7%)
Query: 815 TDADEGTNALFMYTLFGEGK-EMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARD--TG 871
+D D G N+ F Y L G G F +DE TG + I LDRE++ +Y L D TG
Sbjct: 68 SDLDNGNNS-FQYKLLGAGAGSTFIIDERTGDIYAI-QKLDREERSLYILRAQVIDIATG 125
Query: 872 -GLSSEAELIIMIGDENDNKPEF 893
+ E+E +I + D NDN+P+F
Sbjct: 126 RAVEPESEFVIKVSDINDNEPKF 148
Score = 46.8 bits (106), Expect = 0.005
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 18/115 (15%)
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
TF+ID R G +Y ++ DRE + Y I+RA+ V + + +
Sbjct: 89 TFIIDERTGDIYAIQKLDREERSLY--ILRAQ--------------VIDIATGRAVEPES 132
Query: 1365 KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
+ V+++ D+NDN PKF + P +P +P G V+Q+ + P++ R
Sbjct: 133 EFVIKVSDINDNEPKFL--DEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNAR 185
Score = 46.4 bits (105), Expect = 0.006
Identities = 74/325 (22%), Positives = 132/325 (40%), Gaps = 31/325 (9%)
Query: 940 IPENIPIGTTIIKLNALDLDSGLNGQIRY---EFNSEVY-IPPSKLSADALEVKRYFVIN 995
+ E+ P GT+I + A D D G N ++ Y E +S+ + I + + + + + + V
Sbjct: 265 VSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDF 324
Query: 996 ERHGHVIVARSLP----PESEFRLNISALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYN 1051
E H + + PE + + A +++ V+DV D P+F +Y
Sbjct: 325 EHQNHYGIRAKVKNHHVPEQLMKYHTEA-------STTFIKIQVEDV-DEPPLFLLPYYV 376
Query: 1052 FNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRE 1111
F V E +G V ATD D + + + Y I S F I+ G ++ + LDRE
Sbjct: 377 FEVFEETPQGSFVGVVSATDPD-NRKSPIRYSITRSKV---FNIND-NGTITTSNSLDRE 431
Query: 1112 TEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADEL--- 1168
Y L++ A + ++ND++P+F + E ++ + ++
Sbjct: 432 ISAWYNLSITATEK-YNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQT 490
Query: 1169 --SNHNFESVMMIPVY-KATIEENAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQ- 1224
+ ES+ Y ++E+ T+ N + N G L P
Sbjct: 491 ISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISI 550
Query: 1225 --QNLGLPSLSSTAILMVTVADVPD 1247
+ G+PSL+ST L + V D D
Sbjct: 551 LIADNGIPSLTSTNTLTIHVCDCGD 575
Score = 45.2 bits (102), Expect = 0.014
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLFSL----DSVNGSLFLEKELDLDAEHN--LQANT 271
I A D D+G A + Y I +D + F + ++ G + L+K++D + +++ ++A
Sbjct: 278 IMAYDNDIGENAEMDYS-IEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKV 336
Query: 272 FVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMAT 331
V + + + ++I++ D+ D P F + +Y + E P G V V AT
Sbjct: 337 KNHHVPEQLMKYHTEASTTFIKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSAT 395
Query: 332 DKDQGENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
D D Y + K F+I+ +G +T N LDRE + + + A E
Sbjct: 396 DPD-NRKSPIRYSITRSK-VFNIND-NGTITTSNS--LDREISAWYNLSITATE 444
Score = 44.0 bits (99), Expect = 0.032
Identities = 75/338 (22%), Positives = 130/338 (38%), Gaps = 36/338 (10%)
Query: 1027 DNISVRVFVKDVNDHFPVFKK-TWYNFNV-EEAQYTRRVLGKVDATDADFGQNANLTYFI 1084
+N + + V H V + W F V EE T +G++ +D D G N+ Y +
Sbjct: 24 ENSQTKKVKQPVRSHLRVKRGWVWNQFFVPEEMNTTSHHIGQL-RSDLDNGNNS-FQYKL 81
Query: 1085 QPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDV 1144
+ F I TG + +LDRE YIL D D+
Sbjct: 82 LGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDI 141
Query: 1145 NDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFA--- 1201
NDN PKF DE E PE E ++I V A+ ++ G +++
Sbjct: 142 NDNEPKF--LDEPYEAIVPEMSP------EGTLVIQV-TASDADDPSSGNNARLLYSLLQ 192
Query: 1202 NDTDF-IGNGNGLILYSLPQRKNQQN-----------LGLP-SLSSTAILMVTVADVPDE 1248
F + G+I S + Q+ +G P +LS T +++ ++DV D
Sbjct: 193 GQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVND- 251
Query: 1249 VEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEH--YENFKMRYYILNENDTDIRRTF 1306
+KP+F Y L + E+ + ++ ++ EN +M Y I ++
Sbjct: 252 ----NKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIIT 307
Query: 1307 VIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSREL 1344
+ + G + L + D E ++ Y + + + +L
Sbjct: 308 NHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQL 345
Score = 41.1 bits (92), Expect = 0.23
Identities = 18/37 (48%), Positives = 24/37 (64%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+S SV + + DVNDN PIF ++ Y +TV E PTG
Sbjct: 236 LSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTG 272
Score = 38.7 bits (86), Expect = 1.2
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 8/105 (7%)
Query: 242 KLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLND 301
K+F+++ NG++ LD + + + L + A++ N + + + +++L++ND
Sbjct: 412 KVFNIND-NGTITTSNSLDREI-----SAWYNLSITATEKYNIEQISSIPLYVQVLNIND 465
Query: 302 NLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG-ENGEFTYQL 345
+ PEF +Y + EN +G + + A D+D+ E F + L
Sbjct: 466 HAPEFS-QYYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNL 509
Score = 37.9 bits (84), Expect = 2.1
Identities = 14/29 (48%), Positives = 19/29 (65%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
+ + D+NDN P FLD PY V E++P G
Sbjct: 136 IKVSDINDNEPKFLDEPYEAIVPEMSPEG 164
>UniRef50_UPI000155CE9C Cluster: PREDICTED: similar to reproductive
homeobox on X chromosome 8; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to reproductive
homeobox on X chromosome 8 - Ornithorhynchus anatinus
Length = 584
Score = 81.0 bits (191), Expect = 2e-13
Identities = 116/463 (25%), Positives = 192/463 (41%), Gaps = 50/463 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD--LGQNGMVLYD-LQR 501
+ + + D NDN PVF N ++ S++ N++ G V A D D N + Y L +
Sbjct: 38 IVIIVTDINDNQPVFTQEN-FKGSVRENSRPGRPFMHVSATDLDDPSTPNAQLFYRILAQ 96
Query: 502 TSNLTITSPFKINPNTGTVSVAESPILE------GRHALFVEASDQPANPSERRYSLAVV 555
N + F+++ TG +S+ E + LFV +D + +S +
Sbjct: 97 IPNPGVEMYFQVDNQTGAISITREGSKELDVKKNNNYQLFVMVTDM-GGQGDNAFSTSTN 155
Query: 556 TIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYE 615
PD P S + Q+ ND Y+L++ +
Sbjct: 156 VFITIEENIWKSPD-------PIYIAENSTEPHPLKITQVMWNDL----GAHYELVNKEK 204
Query: 616 EG-VPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVVDVNDER 673
+ PF+V++ +G I L R + Y F AL E L+ V V+D+ND
Sbjct: 205 QSRFPFSVDQ-NGSIYATQPLDREEKESYVFYLAALDEMKKALARPLEILVEVIDINDNP 263
Query: 674 GVLLKGAHSPI-IFHVKEN-SAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTD--D 729
V SP+ IF V+EN G+ IG + + + G+G + + I Q T +
Sbjct: 264 PV----CPSPVTIFEVQENEKIGSNIG-VLKASDADKEGSGNSFLSYRILEQIPETSGKN 318
Query: 730 IAIAEDGT-IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFE 788
+ + + T +F +K+D + + E + V Q+ I D ND P+FE
Sbjct: 319 LFLLQLHTGVFQLAQSSPKKQDAPQYNLTVEVSDNVFKTKCAVQINII--DINDQIPIFE 376
Query: 789 HATY-EGFIMENSKIGTEIKMDNIIKATDADE---GTNALFMYTLFGEGKEMFDVD---- 840
+ Y I EN+ +GT I I+A D DE G++ + + G+ + +V+
Sbjct: 377 QSDYGSQTIAENAPVGTTILN---IQARDGDEPFTGSSKIIYKIIQGDPHDTLEVETDPQ 433
Query: 841 ENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMI 883
NTG VK I L + + L+ V +TG L L+I+I
Sbjct: 434 TNTGYVK-IKKPLKKSYPVHSDLTAV-EETGSLDIIISLVIII 474
Score = 70.9 bits (166), Expect = 2e-10
Identities = 59/230 (25%), Positives = 110/230 (47%), Gaps = 21/230 (9%)
Query: 705 MSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRD--VYRMTVIAEFNK 762
++ + N G L+ ++ ++ ++G+I+ +PLDRE+++ V+ + + E K
Sbjct: 185 ITQVMWNDLGAHYELVNKEKQSRFPFSVDQNGSIYATQPLDREEKESYVFYLAALDEMKK 244
Query: 763 GVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDAD-EGT 821
+ A ++ + + D NDNPPV + EN KIG+ I ++KA+DAD EG+
Sbjct: 245 AL---ARPLEILVEVIDINDNPPVCPSPVTIFEVQENEKIGSNI---GVLKASDADKEGS 298
Query: 822 -NALFMYTLFGE-----GKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSS 875
N+ Y + + GK +F + +TGV + S ++ Y L++ D +
Sbjct: 299 GNSFLSYRILEQIPETSGKNLFLLQLHTGVFQLAQSSPKKQDAPQYNLTVEVSD-NVFKT 357
Query: 876 EAELIIMIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKN 925
+ + I I D ND P F Q + S+ N G TI+ ++ ++
Sbjct: 358 KCAVQINIIDINDQIPIFEQSDYGSQTIAE-----NAPVGTTILNIQARD 402
Score = 62.5 bits (145), Expect = 9e-08
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 22/189 (11%)
Query: 769 GIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFM 826
G Y + I + D NDN PVF ++G + ENS+ G + ATD D+ + NA
Sbjct: 34 GPYPIVIIVTDINDNQPVFTQENFKGSVRENSRPGRPFMH---VSATDLDDPSTPNAQLF 90
Query: 827 YTLFGE----GKEM-FDVDENTGVVKFIGD---SLDREKKIMYKLSLVARDTGG-----L 873
Y + + G EM F VD TG + + LD +K Y+L ++ D GG
Sbjct: 91 YRILAQIPNPGVEMYFQVDNQTGAISITREGSKELDVKKNNNYQLFVMVTDMGGQGDNAF 150
Query: 874 SSEAELIIMIGDENDNKPEFNQIEENS----KVRIHRETKLNGTAGFTIIEVKPKNKFAL 929
S+ + I I + P+ I ENS ++I + + A + ++ + +++F
Sbjct: 151 STSTNVFITIEENIWKSPDPIYIAENSTEPHPLKITQVMWNDLGAHYELVNKEKQSRFPF 210
Query: 930 DVDQLGPLF 938
VDQ G ++
Sbjct: 211 SVDQNGSIY 219
Score = 50.4 bits (115), Expect = 4e-04
Identities = 68/289 (23%), Positives = 129/289 (44%), Gaps = 36/289 (12%)
Query: 394 FADSQRIAKWRRQPLETNAPLEKTTYVFPDKVGTKTENIEYYDEQLMSFVNVEVTLLDAN 453
F+ Q + + QPL+ EK +YVF ++ + L + + V ++D N
Sbjct: 210 FSVDQNGSIYATQPLDRE---EKESYVF------YLAALDEMKKALARPLEILVEVIDIN 260
Query: 454 DNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTSNLTITSP--- 510
DN PV PS + F ++ N K+G+ IG +KA D D +G + + TS
Sbjct: 261 DNPPV-CPSPVTIFEVQENEKIGSNIGVLKASDADKEGSGNSFLSYRILEQIPETSGKNL 319
Query: 511 FKINPNTGTVSVAE-SPILEG--RHALFVEASDQPANPSERRYSLAVVTIEVTRGTKGNK 567
F + +TG +A+ SP + ++ L VE SD N + + ++ + I++
Sbjct: 320 FLLQLHTGVFQLAQSSPKKQDAPQYNLTVEVSD---NVFKTKCAVQINIIDI-------N 369
Query: 568 PDIPDFMGAPY-EFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFAVEE-- 624
IP F + Y + N +GT++ I+ D E S +++ +G P E
Sbjct: 370 DQIPIFEQSDYGSQTIAENAPVGTTILNIQARDGDEPFTGSSKIIYKIIQGDPHDTLEVE 429
Query: 625 -----RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVD 668
+G + + L + + P++ + A++E +L I+ + + +V+
Sbjct: 430 TDPQTNTGYVKIKKPLKK-SYPVHS-DLTAVEETGSLDIIISLVIIIVN 476
Score = 39.9 bits (89), Expect = 0.53
Identities = 80/417 (19%), Positives = 158/417 (37%), Gaps = 53/417 (12%)
Query: 1017 ISALD--GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADF 1074
++ LD G + + + V D+ND+ PVF + + +V E R V ATD D
Sbjct: 22 VAGLDARGTTVEGPYPIVIIVTDINDNQPVFTQENFKGSVRENSRPGRPFMHVSATDLDD 81
Query: 1075 GQNANLTYF------IQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXX 1128
N F I ++ F++ TG +S+ E +E + V ++N
Sbjct: 82 PSTPNAQLFYRILAQIPNPGVEMYFQVDNQTGAISITREGSKELD-------VKKNNNYQ 134
Query: 1129 XXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATIEE 1188
+ ++ F +E + WK P+ ++ ++ E + + + +
Sbjct: 135 LFVMVTDMGGQGDNAFSTSTNVFITIEENI-WKSPDPIYIAENSTEP-HPLKITQVMWND 192
Query: 1189 NAPIGTTVAKVFANDTDFIGNGNGLILYSLPQRKNQQNLGL----------PSLSSTAIL 1238
V K + F + NG I + P + ++ + +L+ +
Sbjct: 193 LGAHYELVNKEKQSRFPFSVDQNGSIYATQPLDREEKESYVFYLAALDEMKKALARPLEI 252
Query: 1239 MVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLT--EHYENFKMRYYILN 1296
+V V D+ D + PV I +E++ E + + + ++ + E N + Y IL
Sbjct: 253 LVEVIDINDNPPVCPSPVTI---FEVQENEKIGSNIGVLKASDADKEGSGNSFLSYRILE 309
Query: 1297 E-NDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDV 1355
+ +T + F++ G L +S ++ ++ P Y + +V
Sbjct: 310 QIPETSGKNLFLLQLHTGVFQLAQSSPKK-----------------QDAPQ--YNLTVEV 350
Query: 1356 LEGMTKYDVKVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHP 1412
+ + K V + I D+ND P F + T I AP G ++ ++ G P
Sbjct: 351 SDNVFKTKCAVQINIIDINDQIPIFEQSDYGSQT-IAENAPVGTTILNIQARDGDEP 406
Score = 39.5 bits (88), Expect = 0.69
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 11/135 (8%)
Query: 215 PEPIHAIDQDLGVGATLRYELISGN--DRKLFSLDSVNGSLFLEKELDLDAEHNLQANTF 272
P P+ I Q + YEL++ R FS+D NGS++ + LD + + +
Sbjct: 180 PHPLK-ITQVMWNDLGAHYELVNKEKQSRFPFSVDQ-NGSIYATQPLDREEKESYVFYLA 237
Query: 273 VLQVQASQLNNPLKTAQARVEIELLDLNDNLP--EFEVDFYNISIVENLPNGFSVLQVMA 330
L L PL+ + +E++D+NDN P V + + E + + VL+
Sbjct: 238 ALDEMKKALARPLE-----ILVEVIDINDNPPVCPSPVTIFEVQENEKIGSNIGVLKASD 292
Query: 331 TDKDQGENGEFTYQL 345
DK+ N +Y++
Sbjct: 293 ADKEGSGNSFLSYRI 307
Score = 36.3 bits (80), Expect = 6.5
Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 18/172 (10%)
Query: 937 LFLIPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINE 996
+F + EN IG+ I L A D D +G + IP + K F++
Sbjct: 272 IFEVQENEKIGSNIGVLKASDADKEGSGNSFLSYRILEQIPETS-------GKNLFLLQL 324
Query: 997 RHGHVIVARSLPPESEF-RLNISALDGGNL-NDNISVRVFVKDVNDHFPVFKKTWYNFN- 1053
G +A+S P + + + N++ N+ +V++ + D+ND P+F+++ Y
Sbjct: 325 HTGVFQLAQSSPKKQDAPQYNLTVEVSDNVFKTKCAVQINIIDINDQIPIFEQSDYGSQT 384
Query: 1054 -VEEAQYTRRVLGKVDATDAD--FGQNANLTYFI---QPSDTDLPFEISPLT 1099
E A +L + A D D F ++ + Y I P DT L E P T
Sbjct: 385 IAENAPVGTTIL-NIQARDGDEPFTGSSKIIYKIIQGDPHDT-LEVETDPQT 434
>UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome
shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 11
SCAF14479, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 908
Score = 81.0 bits (191), Expect = 2e-13
Identities = 55/170 (32%), Positives = 83/170 (48%), Gaps = 18/170 (10%)
Query: 736 GTIFTQKPLDREKRDVYRMTVIA-EFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEG 794
G +F +PLDRE R + + A + N + ++ IY+ D NDN P F++ Y G
Sbjct: 252 GNMFVTQPLDREDRASFHLRAHAVDMNGNQVENP--IELYIYVIDMNDNRPEFQNQVYNG 309
Query: 795 FIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLFGEG-----KEMFDVDENTGVVK 847
+ E SK G+ + + ATD+D+ T N + Y + + MF ++ TG +
Sbjct: 310 SVAEGSKPGSSVMQ---VTATDSDDSTTANGMVRYRILSQTPHNPIPNMFTINSETGDIV 366
Query: 848 FIGDSLDREKKIMYKLSLVARD-----TGGLSSEAELIIMIGDENDNKPE 892
+ LDREK Y + + A D GLS+ A +I I D NDN PE
Sbjct: 367 TVSAGLDREKVSQYTIIVQATDMEGNLNFGLSNTATALISITDINDNPPE 416
Score = 69.3 bits (162), Expect = 8e-10
Identities = 53/176 (30%), Positives = 91/176 (51%), Gaps = 20/176 (11%)
Query: 222 DQDLGVGATLRYELI-SGNDRK---LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQ 277
DQD VG +RY + +G D+ ++++D ++G++F+ + LD + + + +
Sbjct: 221 DQDKDVG--IRYSITGAGADQPPSGIYNIDPISGNMFVTQPLDREDRASFHLRAHAVDMN 278
Query: 278 ASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQG- 336
+Q+ NP++ + I ++D+NDN PEF+ YN S+ E G SV+QV ATD D
Sbjct: 279 GNQVENPIE-----LYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDST 333
Query: 337 -ENGEFTYQL-----DDP-KGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKE 385
NG Y++ +P F+I+ +G + V LDRE S + V A +
Sbjct: 334 TANGMVRYRILSQTPHNPIPNMFTINSETGDI-VTVSAGLDREKVSQYTIIVQATD 388
Score = 58.4 bits (135), Expect = 1e-06
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 999 GHVIVARSLPPE--SEFRLNISALD--GGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNV 1054
G++ V + L E + F L A+D G + + I + ++V D+ND+ P F+ YN +V
Sbjct: 252 GNMFVTQPLDREDRASFHLRAHAVDMNGNQVENPIELYIYVIDMNDNRPEFQNQVYNGSV 311
Query: 1055 EEAQYTRRVLGKVDATDADFGQNAN--LTYFI--QPSDTDLP--FEISPLTG-VLSVNGE 1107
E + +V ATD+D AN + Y I Q +P F I+ TG +++V+
Sbjct: 312 AEGSKPGSSVMQVTATDSDDSTTANGMVRYRILSQTPHNPIPNMFTINSETGDIVTVSAG 371
Query: 1108 LDRETEDKYILTVVARD--NGXXXXXXXXXXXXXXXXDVNDNSPK 1150
LDRE +Y + V A D D+NDN P+
Sbjct: 372 LDREKVSQYTIIVQATDMEGNLNFGLSNTATALISITDINDNPPE 416
Score = 57.2 bits (132), Expect = 3e-06
Identities = 98/435 (22%), Positives = 161/435 (37%), Gaps = 46/435 (10%)
Query: 511 FKINPNTGTVSVAESPILEGRHALFVEAS--DQPANPSERRYSLAVVTIEVTRGTKGNKP 568
+ I+P +G + V + E R + + A D N E L + I++ N+P
Sbjct: 245 YNIDPISGNMFVTQPLDREDRASFHLRAHAVDMNGNQVENPIELYIYVIDMN----DNRP 300
Query: 569 DIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQND----VSYDLLHGYEEG-VP--FA 621
+ F Y V G+SV Q+ D+ + V Y +L +P F
Sbjct: 301 E---FQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANGMVRYRILSQTPHNPIPNMFT 357
Query: 622 VEERSG-VITVVDDLSRYNRPMYDF--EAVALQENANLSIVTNAT--VHVVDVNDERGVL 676
+ +G ++TV L R Y +A ++ N N + AT + + D+ND L
Sbjct: 358 INSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLNFGLSNTATALISITDINDNPPEL 417
Query: 677 LKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI---AIA 733
S V EN + + + + V ++ I I
Sbjct: 418 TVRTFSG---EVPENKVNVVVTNLTVVDRDQPHSPNWNAVYRIVGGDPTGHFTIHTNPIT 474
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG-----AGIYQVTIYIEDENDNPPVFE 788
+G + KP+D E + +TV+ + SG VTI ++D N+ PPVF
Sbjct: 475 NEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSSLQSTAGVTISVQDVNE-PPVFP 533
Query: 789 HATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKF 848
E GT + + A D D + + Y+ + ++ G +
Sbjct: 534 VNPKMIRFEEGVPAGTTL---TVFAAQDPDRFIHQIVRYSKLSDPANWLKINRTNGQITT 590
Query: 849 IGDSLDRE----KKIMYKLSLVARDTG-----GLSSEAELIIMIGDENDNKPEFNQIEEN 899
+ LDRE K +Y+ + +A D G S L I + D NDN PE E
Sbjct: 591 MA-LLDRESMFVKNNVYEATFLAFDNGKSGSPPASGTGTLQIYLIDVNDNAPELIPREAQ 649
Query: 900 SKVRIHRETKLNGTA 914
R +++N TA
Sbjct: 650 LCDRPRPNSRINITA 664
Score = 52.8 bits (121), Expect = 7e-05
Identities = 88/377 (23%), Positives = 151/377 (40%), Gaps = 33/377 (8%)
Query: 432 IEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD--L 489
++ Q+ + + + + ++D NDN P F + +Y S+ +K G+ + +V A D D
Sbjct: 275 VDMNGNQVENPIELYIYVIDMNDNRPEF-QNQVYNGSVAEGSKPGSSVMQVTATDSDDST 333
Query: 490 GQNGMVLYD-LQRTSNLTITSPFKINPNTG---TVSVAESPILEGRHALFVEASDQPANP 545
NGMV Y L +T + I + F IN TG TVS ++ + V+A+D N
Sbjct: 334 TANGMVRYRILSQTPHNPIPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNL 393
Query: 546 SERRYSLAVVTIEVTRGTKGNKPD--IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQ 603
+ + A I +T N P+ + F G E V NV + T++ + +
Sbjct: 394 NFGLSNTATALISIT-DINDNPPELTVRTFSGEVPENKV--NV-VVTNLTVVDRDQPHSP 449
Query: 604 N-DVSYDLLHGYEEGVPFAVE----ERSGVITVVDDLSRYNRPMYDFEAVALQENANLSI 658
N + Y ++ G G F + G++TV+ + + V + S
Sbjct: 450 NWNAVYRIVGGDPTG-HFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASG 508
Query: 659 VTNATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
+ ++ V + ++ + P +F V G T ++
Sbjct: 509 IQSSLQSTAGVT----ISVQDVNEPPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIH 564
Query: 719 LIANQQDVTDD---IAI-AEDGTIFTQKPLDRE----KRDVYRMTVIAEFN--KGVISGA 768
I ++D + I +G I T LDRE K +VY T +A N G +
Sbjct: 565 QIVRYSKLSDPANWLKINRTNGQITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPAS 624
Query: 769 GIYQVTIYIEDENDNPP 785
G + IY+ D NDN P
Sbjct: 625 GTGTLQIYLIDVNDNAP 641
Score = 41.5 bits (93), Expect = 0.17
Identities = 38/168 (22%), Positives = 82/168 (48%), Gaps = 17/168 (10%)
Query: 46 SDSPQNVVKFRLGCDFDEGDDLVRIGAGLNQ--ISAYLSVTVYIEDVNDNVPIFLDTPYH 103
S +P N + + + GD +V + AGL++ +S Y ++ V D+ N+ L
Sbjct: 345 SQTPHNPIPNMFTINSETGD-IVTVSAGLDREKVSQY-TIIVQATDMEGNLNFGLSNTAT 402
Query: 104 --VTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPRGLTIFKDIRAFDRDKPNTPNSDVHY 161
+++ ++ + + + P + + V LT+ DRD+P++PN + Y
Sbjct: 403 ALISITDINDNPPELTVRTFSGEVPENKVNVVVTN-LTVV------DRDQPHSPNWNAVY 455
Query: 162 SIVSGNDDGHFALES---SHKPVLLLRKVLDYDAGDKEFQLVIMASGK 206
IV G+ GHF + + +++ +L + K +D++ ++ F L ++ S +
Sbjct: 456 RIVGGDPTGHFTIHTNPITNEGMLTVIKPVDFEM-NRAFGLTVVVSNQ 502
Score = 40.3 bits (90), Expect = 0.40
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 9/92 (9%)
Query: 817 ADEGTNALFMYTLFGEGKE-----MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTG 871
+D+ + Y++ G G + ++++D +G + F+ LDRE + + L A D
Sbjct: 220 SDQDKDVGIRYSITGAGADQPPSGIYNIDPISGNM-FVTQPLDREDRASFHLRAHAVDMN 278
Query: 872 G--LSSEAELIIMIGDENDNKPEF-NQIEENS 900
G + + EL I + D NDN+PEF NQ+ S
Sbjct: 279 GNQVENPIELYIYVIDMNDNRPEFQNQVYNGS 310
Score = 40.3 bits (90), Expect = 0.40
Identities = 49/192 (25%), Positives = 84/192 (43%), Gaps = 25/192 (13%)
Query: 180 PVLLLRKVLDYDAGDKEFQLVI----MASGKRIHKEILFPEPIHAIDQDLGVGAT--LRY 233
P+ L V+D + EFQ + +A G + ++ + A D D A +RY
Sbjct: 285 PIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVM---QVTATDSDDSTTANGMVRY 341
Query: 234 ELISGNDRK----LFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLK--- 286
++S +F+++S G + + LD E + + + + VQA+ + L
Sbjct: 342 RILSQTPHNPIPNMFTINSETGDI-VTVSAGLDRE---KVSQYTIIVQATDMEGNLNFGL 397
Query: 287 TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQ--GENGEFTYQ 344
+ A I + D+NDN PE V ++ + EN N V + D+DQ N Y+
Sbjct: 398 SNTATALISITDINDNPPELTVRTFSGEVPENKVN-VVVTNLTVVDRDQPHSPNWNAVYR 456
Query: 345 L--DDPKGAFSI 354
+ DP G F+I
Sbjct: 457 IVGGDPTGHFTI 468
>UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep:
Protocadherin - Ciona savignyi (Pacific transparent sea
squirt)
Length = 1177
Score = 81.0 bits (191), Expect = 2e-13
Identities = 120/521 (23%), Positives = 199/521 (38%), Gaps = 80/521 (15%)
Query: 661 NATVHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI 720
N + + D ND H PII +V E+ I + + + + I
Sbjct: 131 NLEIVITDTNDNAPTF---PHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTI 187
Query: 721 ANQQDVTDDIAIAEDGT----IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIY 776
A Q + I E G + LD E + V+ +T+ A N G + + I
Sbjct: 188 APSQPFGVNQYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDN-GTPPLSNNVALRIL 246
Query: 777 IEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM 836
+ D ND+ PVF + + + EN G + + A D D G N Y
Sbjct: 247 VTDANDHSPVFAQSEFVKELKENQPPGFITR----VHAVDRDSGNNGRVQY--------- 293
Query: 837 FDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI 896
F+GD + + ++L V +DTG ++ L+ +N ++ + +
Sbjct: 294 -----------FLGDE---SEAVSHQLVTVDKDTGDVT----LV-----QNLDRETHDGM 330
Query: 897 EENSKVRIHRETKLNGTAGFTIIEVKPKNKFA------LDVDQLGPLFLIPENIPIGTTI 950
+ R T + + ++ + N A VD G I E PIGT +
Sbjct: 331 RILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTYV 390
Query: 951 IKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHVIVARSLPPE 1010
++A D D G N ++ + V+ P + +FV+ G + L E
Sbjct: 391 AYVSASDADHGKNSEVDISIRTLVFGEPEYANTG------HFVL-AADGLIGTGLELDRE 443
Query: 1011 --SEFRLNISALDGGNLNDNI--SVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGK 1066
+ +++ + A D G++ + ++ V + D ND+ PVF+K Y + EA +
Sbjct: 444 IQNSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADGVGTTVTT 503
Query: 1067 VDATDADF----------------GQNANLTYFIQPSDTDLPFEISPLTGVLSVNGELDR 1110
V ATD D N +TY I D F I+ TG +++ LDR
Sbjct: 504 VSATDKDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDDN--TFSINAETGEITLVRPLDR 561
Query: 1111 ETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF 1151
E + + +T++ARD G DVNDN P F
Sbjct: 562 EGQSDWEVTIIARDGG-SPYKESTCILKVVVSDVNDNRPLF 601
Score = 79.0 bits (186), Expect = 9e-13
Identities = 137/557 (24%), Positives = 226/557 (40%), Gaps = 80/557 (14%)
Query: 547 ERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVG----QIRVNDAFE 602
+R +SL + I +T T N P P P V +V + + Q R D+
Sbjct: 124 QRVFSLLNLEIVIT-DTNDNAPTFPH---KPIIVNVSESVTVNDIINLDSFQARDLDSGN 179
Query: 603 QNDVSYDLLHGYEEGVPFAVEE--RSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVT 660
+ ++Y + GV ++E R + +V Y + +N +
Sbjct: 180 NSAITYTIAPSQPFGVNQYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDNGTPPLSN 239
Query: 661 NATVHVV--DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF 718
N + ++ D ND V A S + +KEN I ++ + S GN G V++
Sbjct: 240 NVALRILVTDANDHSPVF---AQSEFVKELKENQPPGFITRVHAVDRDS--GNN-GRVQY 293
Query: 719 LIANQQDVTDDIAIAED---GTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTI 775
+ ++ + + D G + + LDRE D R+ + A + + + +
Sbjct: 294 FLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSSRMWLVL 353
Query: 776 YIEDENDNPP------VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNA---LFM 826
I+D+NDN P + + +I E S IGT + + A+DAD G N+ + +
Sbjct: 354 RIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTYVA---YVSASDADHGKNSEVDISI 410
Query: 827 YTL-FGEGKEMFDVDENTGVVKFIGD--SLDREKKIMYKLSLVARDTGGL--SSEAELII 881
TL FGE + IG LDRE + YK+ + ARD G + SS + +
Sbjct: 411 RTLVFGEPEYANTGHFVLAADGLIGTGLELDREIQNSYKVVVEARDAGDVPRSSFNNITV 470
Query: 882 MIGDENDNKPEFNQIEENSKVRIHRETKLNGTAGFTIIEVKPKNKFALDVDQLGPLFLIP 941
+I DENDN P F + V ++ +G G T+ V A D D L P
Sbjct: 471 IILDENDNAPVFQK-----PVYPVTLSEADG-VGTTVTTVS-----ATDKDALFP----- 514
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
P+ T K ++ +NG++ Y +S+ F IN G +
Sbjct: 515 ---PVWT---KNKKKEIVPSMNGKVTYLIDSD---------------DNTFSINAETGEI 553
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
+ R L E S++ + I A DGG+ ++V V DVND+ P+F + + A
Sbjct: 554 TLVRPLDREGQSDWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYA 613
Query: 1058 QYTR-RVLGKVDATDAD 1073
R V+ ++ A D D
Sbjct: 614 TILRDDVITRIQAVDYD 630
Score = 72.9 bits (171), Expect = 6e-11
Identities = 77/259 (29%), Positives = 113/259 (43%), Gaps = 39/259 (15%)
Query: 955 ALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINER-HGHVIVARSLPPESE- 1012
A DLDSG N I Y I PS+ V +Y R H +IV L E++
Sbjct: 172 ARDLDSGNNSAITYT------IAPSQ----PFGVNQYIDEAGRPHLQLIVTSELDYETKQ 221
Query: 1013 -FRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDA 1069
L + A D G L++N+++R+ V D NDH PVF ++ + ++E Q + +V A
Sbjct: 222 VHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKENQ-PPGFITRVHA 280
Query: 1070 TDADFGQNANLTYFIQPSDTDLPFEISPL---TGVLSVNGELDRETEDKYILTVVARDNG 1126
D D G N + YF+ + ++ + TG +++ LDRET D + + ARD+
Sbjct: 281 VDRDSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSA 340
Query: 1127 XXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKATI 1186
D NDN+P N NF ++ A I
Sbjct: 341 PTNQRSSRMWLVLRIDDDNDNAPTI------------------NMNF--IVDADGQTAYI 380
Query: 1187 EENAPIGTTVAKVFANDTD 1205
E +PIGT VA V A+D D
Sbjct: 381 SEASPIGTYVAYVSASDAD 399
Score = 68.9 bits (161), Expect = 1e-09
Identities = 99/411 (24%), Positives = 169/411 (41%), Gaps = 37/411 (9%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L + V + + + DAND++PVF S + +K N G I +V AVD D G NG V Y
Sbjct: 237 LSNNVALRILVTDANDHSPVFAQSEFVK-ELKENQPPG-FITRVHAVDRDSGNNGRVQYF 294
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILEGRHALFVEASDQPANPSERRYSLAVVTIE 558
L S ++ +TG V++ ++ E + + + + P+ +R S + +
Sbjct: 295 LGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSSRMWLVLR 354
Query: 559 VTRGTKGNKPDI-PDFM--GAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYD-----L 610
+ N P I +F+ ++ IGT V + +DA + D L
Sbjct: 355 ID-DDNDNAPTINMNFIVDADGQTAYISEASPIGTYVAYVSASDADHGKNSEVDISIRTL 413
Query: 611 LHGYEE--GVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQE-NANLSIVTNATVHVV 667
+ G E V G+I +L R + Y A + S N TV ++
Sbjct: 414 VFGEPEYANTGHFVLAADGLIGTGLELDREIQNSYKVVVEARDAGDVPRSSFNNITVIIL 473
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIY-------------GNGTG 714
D ND V K + P+ + + G + + T+ +++ + G
Sbjct: 474 DENDNAPVFQKPVY-PVTLS-EADGVGTTVTTVSATDKDALFPPVWTKNKKKEIVPSMNG 531
Query: 715 NVRFLIANQQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVT 774
V +LI + D T I AE G I +PLDRE + + +T+IA + G +
Sbjct: 532 KVTYLI-DSDDNTFSIN-AETGEITLVRPLDREGQSDWEVTIIAR-DGGSPYKESTCILK 588
Query: 775 IYIEDENDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALF 825
+ + D NDN P+F + ++NS I D++I A + + +F
Sbjct: 589 VVVSDVNDNRPLFINPA-----IDNSTAYATILRDDVITRIQAVDYDSPMF 634
Score = 55.2 bits (127), Expect = 1e-05
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 10/122 (8%)
Query: 274 LQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDK 333
L + A+ P + + I + D ND+ P F + + EN P GF + +V A D+
Sbjct: 225 LTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKENQPPGF-ITRVHAVDR 283
Query: 334 DQGENGEFTYQLDDPKGAFS-----IDPRSGWLT-VRNQTVLDREAHSSLRMKVYAKETN 387
D G NG Y L D A S +D +G +T V+N LDRE H +R+ + A+++
Sbjct: 284 DSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQN---LDRETHDGMRILIEARDSA 340
Query: 388 PS 389
P+
Sbjct: 341 PT 342
Score = 53.6 bits (123), Expect = 4e-05
Identities = 52/212 (24%), Positives = 97/212 (45%), Gaps = 25/212 (11%)
Query: 261 LDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLP 320
L+ + +Q N++ + V+A + +++ + + +LD NDN P F+ Y +++ E
Sbjct: 438 LELDREIQ-NSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADG 496
Query: 321 NGFSVLQVMATDKD----------------QGENGEFTYQLDDPKGAFSIDPRSGWLTVR 364
G +V V ATDKD NG+ TY +D FSI+ +G +T+
Sbjct: 497 VGTTVTTVSATDKDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDDNTFSINAETGEITLV 556
Query: 365 NQTVLDREAHSSLRMKVYAKE-TNPSVVGTFADSQRIAKWR-RQPLETNAPLEKTT---Y 419
LDRE S + + A++ +P T ++ +PL N ++ +T
Sbjct: 557 RP--LDREGQSDWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYAT 614
Query: 420 VFPDKVGTKTENIEYYDEQLMSFVNVEVTLLD 451
+ D V T+ + ++ YD + S V + + +D
Sbjct: 615 ILRDDVITRIQAVD-YDSPMFSKVEISLLSVD 645
Score = 50.8 bits (116), Expect = 3e-04
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 13/142 (9%)
Query: 1029 ISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRV--LGKVDATDADFGQNANLTYFIQP 1086
+++ + + D ND+ P F NV E+ + L A D D G N+ +TY I P
Sbjct: 130 LNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAP 189
Query: 1087 SDTDLPFEISPLTG-------VLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXXXX 1139
S PF ++ L V ELD ET+ + LT+ A DNG
Sbjct: 190 SQ---PFGVNQYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDNG-TPPLSNNVALRI 245
Query: 1140 XXXDVNDNSPKFYAFDELLEWK 1161
D ND+SP F + + E K
Sbjct: 246 LVTDANDHSPVFAQSEFVKELK 267
Score = 45.2 bits (102), Expect = 0.014
Identities = 63/288 (21%), Positives = 118/288 (40%), Gaps = 30/288 (10%)
Query: 76 QISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGE----KAFIFLIAPIGPSLTIP 131
++ + L++ + I D NDN P F P V V E + +F G + I
Sbjct: 125 RVFSLLNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAIT 184
Query: 132 LTV----PRGLTIFKD------IRAFDRDKPNTPNSDVHYSIVSGNDDGHFALESSHKPV 181
T+ P G+ + D ++ + + VH+ + D+G L ++ V
Sbjct: 185 YTIAPSQPFGVNQYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDNGTPPLSNN---V 241
Query: 182 LLLRKVLDYDAGDKEFQLVIMASGKRIHKEILFPEPIHAIDQDLGVGATLRYELISGND- 240
L V D + F + ++ F +HA+D+D G ++Y L ++
Sbjct: 242 ALRILVTDANDHSPVFAQSEFVKELKENQPPGFITRVHAVDRDSGNNGRVQYFLGDESEA 301
Query: 241 --RKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLD 298
+L ++D G + L + LD + ++ +++ + S N ++++ + + + D
Sbjct: 302 VSHQLVTVDKDTGDVTLVQNLDRETHDGMR---ILIEARDSAPTNQ-RSSRMWLVLRIDD 357
Query: 299 LNDNLPEFEVDFY------NISIVENLPNGFSVLQVMATDKDQGENGE 340
NDN P ++F I E P G V V A+D D G+N E
Sbjct: 358 DNDNAPTINMNFIVDADGQTAYISEASPIGTYVAYVSASDADHGKNSE 405
Score = 41.5 bits (93), Expect = 0.17
Identities = 54/237 (22%), Positives = 92/237 (38%), Gaps = 29/237 (12%)
Query: 1228 GLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYE- 1286
G P LS+ L + V D D PVF + E++EN P + ++ +
Sbjct: 233 GTPPLSNNVALRILVTDANDH-----SPVFAQSEFVKELKEN-QPPGFITRVHAVDRDSG 286
Query: 1287 -NFKMRYYILNENDTDIRRTFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELP 1345
N +++Y++ +E++ + +D G + LV++ DRE D +++ A + +
Sbjct: 287 NNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRS 346
Query: 1346 HMIYPVAEDVLEGMTKYDVKVVVRIKDVNDNSP----KFTNGNRPLVTAIPTTAPFGYQV 1401
++ +V+RI D NDN+P F I +P G V
Sbjct: 347 SRMW----------------LVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTYV 390
Query: 1402 MQLKGAIGHHPTASRTVRADTDELVFFERLSLNGLTSPQATDSDIGINADIRYQILN 1458
+ + H S V LVF E N A D IG ++ +I N
Sbjct: 391 AYVSASDADHGKNSE-VDISIRTLVFGEPEYANTGHFVLAADGLIGTGLELDREIQN 446
Score = 41.1 bits (92), Expect = 0.23
Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 11/138 (7%)
Query: 364 RNQTVLDREAHSSLRMKVYAKETNPSVVGTFADSQRIAKWRRQPLETNAPLEKTTYVFPD 423
RN +L+++ HSS A+ P V S I RR ET K +
Sbjct: 59 RNFKLLNQKFHSSSMFSPSARRHRPDAVDLGTSSGLITLRRRVDRETECGQAKECII--- 115
Query: 424 KVGTKTENIEYYDEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG--K 481
K + + +++ S +N+E+ + D NDN P F P ++ + V +I
Sbjct: 116 ----KVQAV-MLPQRVFSLLNLEIVITDTNDNAPTF-PHKPIIVNVSESVTVNDIINLDS 169
Query: 482 VKAVDPDLGQNGMVLYDL 499
+A D D G N + Y +
Sbjct: 170 FQARDLDSGNNSAITYTI 187
Score = 37.5 bits (83), Expect = 2.8
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 13/124 (10%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMV--------- 495
++V + D NDN P+F+ + + + VI +++AVD D V
Sbjct: 587 LKVVVSDVNDNRPLFINPAIDNSTAYATILRDDVITRIQAVDYDSPMFSKVEISLLSVDG 646
Query: 496 LYDLQRTSNLTITSPFKINPNTG----TVSVAESPILEGRHALFVEASDQPANPSERRYS 551
L Q T + S F ++ TG +S A+ + G H + V+A+D P E R S
Sbjct: 647 LKSTQETDGVEPYSFFVLDRATGDLRLNMSTADLNDIVGSHVIVVKATDNGQPPLESRTS 706
Query: 552 LAVV 555
+ ++
Sbjct: 707 ITII 710
Score = 37.1 bits (82), Expect = 3.7
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
Query: 246 LDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPE 305
L + +G + L + +D + E QA +++VQA L + + +EI + D NDN P
Sbjct: 88 LGTSSGLITLRRRVDRETECG-QAKECIIKVQAVMLPQRVFSL-LNLEIVITDTNDNAPT 145
Query: 306 F--EVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQLDDPKGAFSID 355
F + N+S + + ++ A D D G N TY + P F ++
Sbjct: 146 FPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTI-APSQPFGVN 196
>UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep:
KIAA0811 protein - Homo sapiens (Human)
Length = 1123
Score = 80.6 bits (190), Expect = 3e-13
Identities = 101/417 (24%), Positives = 172/417 (41%), Gaps = 29/417 (6%)
Query: 488 DLGQNGMVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILEGRHA---LFVEASDQPAN 544
D G N V+Y L ++ F I+ TG + + E P+ A L V ASD
Sbjct: 1 DQGANAQVVYSLPDSAE----GHFSIDATTGVIRL-EKPLQVRPQAPLELTVRASDL-GT 54
Query: 545 PSERRYSLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN 604
P +L VT+ V G + +P F+ + V + GT V Q+
Sbjct: 55 PIPLS-TLGTVTVSVV----GLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAE 109
Query: 605 DVSYDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEA-VALQENANLSIVTNAT 663
Y ++ G E+G F ++ R+G++ V L P Y + + +++LS VT
Sbjct: 110 KTGYRVVSGNEQG-RFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVM 168
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHT-NMSSIYGNGTGNVRFLIAN 722
V++ DVN+ R + +S V EN A +G + T + + G ++ + +
Sbjct: 169 VNITDVNEHRPQFPQDPYST---RVLEN---ALVGDVILTVSATDEDGPLNSDITYSLIG 222
Query: 723 QQDVTDDIAIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
+ + G + K LDRE+ Y + + A + G + I + D ND
Sbjct: 223 GNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRAT-DSGQPPLHEDTDIAIQVADVND 281
Query: 783 NPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDEN 842
NPP F Y + ENS IG+++ + I+ D+ E G F V +
Sbjct: 282 NPPRFFQLNYSTTVQENSPIGSKV-LQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPD 340
Query: 843 TGVVKFIGDSLDREKKIMYKLSLVARDTG--GLSSEAELIIMIGDENDNKPEFNQIE 897
+V + L R + Y+L + A D+G LSS + + + +++ P +E
Sbjct: 341 GWLV--TAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAPSALPLE 395
Score = 77.8 bits (183), Expect = 2e-12
Identities = 48/156 (30%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 233 YELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARV 292
Y ++SGN++ F LD+ G L++ LD + + L ++ S+ ++ + V
Sbjct: 113 YRVVSGNEQGRFRLDARTGILYVNASLDFETSPK-----YFLSIECSRKSSSSLSDVTTV 167
Query: 293 EIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFTYQL--DDPKG 350
+ + D+N++ P+F D Y+ ++EN G +L V ATD+D N + TY L + G
Sbjct: 168 MVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLG 227
Query: 351 AFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
F+I P+ G L V LDRE SS +K+ A ++
Sbjct: 228 HFTIHPKKGELQVAK--ALDREQASSYSLKLRATDS 261
Score = 77.0 bits (181), Expect = 4e-12
Identities = 84/323 (26%), Positives = 141/323 (43%), Gaps = 27/323 (8%)
Query: 77 ISAYLSVTVYIEDVNDNVPIFLDTPYHVTVDELTPTGEKAFIFLIAPIGPSLTIPLTVPR 136
+S +VTV + + D +P+FL+T + V V E P G + + +A +LT P
Sbjct: 58 LSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTE--VLQLA----TLTRPGAEKT 111
Query: 137 GLTIFK-DIRAFDRDKPNTPNSDVHYSIVSGNDDGHF-ALESSHKPVLLLRKVLDY---- 190
G + + + R T V+ S+ +F ++E S K L V
Sbjct: 112 GYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNI 171
Query: 191 -DAGDKEFQLVIMASGKRIHKEILFPEPI---HAIDQDLGVGATLRYELISGNDRKLFSL 246
D + Q R+ + L + I A D+D + + + Y LI GN F++
Sbjct: 172 TDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTI 231
Query: 247 DSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEF 306
G L + K LD + QA+++ L+++A+ P + I++ D+NDN P F
Sbjct: 232 HPKKGELQVAKALDRE-----QASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRF 286
Query: 307 EVDFYNISIVENLPNGFSVLQVMATDKDQGENG---EFTYQLDDPKGAFSIDPRSGWLTV 363
Y+ ++ EN P G VLQ++ +D D ENG F + AF + P GWL
Sbjct: 287 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVT 345
Query: 364 RNQTVLDREAHSSLRMKVYAKET 386
L R A ++++ A ++
Sbjct: 346 AEG--LSRRAQEWYQLQIQASDS 366
Score = 73.3 bits (172), Expect = 5e-11
Identities = 77/290 (26%), Positives = 128/290 (44%), Gaps = 19/290 (6%)
Query: 620 FAVEERSGVITVVDDLS-RYNRPM-YDFEAVALQENANLSIVTNATVHVVDVNDERGVLL 677
F+++ +GVI + L R P+ A L LS + TV VV + D V L
Sbjct: 20 FSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFL 79
Query: 678 KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGT 737
HS + ++ G + Q+ ++ TG R + N+Q A G
Sbjct: 80 NTEHSVQV--PEDAPPGTEVLQL--ATLTRPGAEKTG-YRVVSGNEQGRFR--LDARTGI 132
Query: 738 IFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIM 797
++ LD E Y +++ K S + + V + I D N++ P F Y ++
Sbjct: 133 LYVNASLDFETSPKYFLSIECS-RKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVL 191
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEM--FDVDENTGVVKFIGDSLDR 855
EN+ +G I + ATD D N+ Y+L G G ++ F + G ++ + +LDR
Sbjct: 192 ENALVGDVILT---VSATDEDGPLNSDITYSLIG-GNQLGHFTIHPKKGELQ-VAKALDR 246
Query: 856 EKKIMYKLSLVARDTGG--LSSEAELIIMIGDENDNKPEFNQIEENSKVR 903
E+ Y L L A D+G L + ++ I + D NDN P F Q+ ++ V+
Sbjct: 247 EQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQ 296
Score = 70.1 bits (164), Expect = 4e-10
Identities = 66/223 (29%), Positives = 98/223 (43%), Gaps = 31/223 (13%)
Query: 992 FVINERHGHVIVARSLPPES--EFRLNI--SALDGGNLNDNISVRVFVKDVNDHFPVFKK 1047
F ++ R G + V SL E+ ++ L+I S +L+D +V V + DVN+H P F +
Sbjct: 124 FRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQ 183
Query: 1048 TWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVNGE 1107
Y+ V E V+ V ATD D N+++TY + + F I P G L V
Sbjct: 184 DPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKA 243
Query: 1108 LDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKFYAFDELLEWKHPEADE 1167
LDRE Y L + A D+G DVNDN P+F+ +
Sbjct: 244 LDREQASSYSLKLRATDSG-QPPLHEDTDIAIQVADVNDNPPRFFQLN------------ 290
Query: 1168 LSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNG 1210
Y T++EN+PIG+ V ++ +D D NG
Sbjct: 291 --------------YSTTVQENSPIGSKVLQLILSDPDSPENG 319
Score = 55.2 bits (127), Expect = 1e-05
Identities = 64/235 (27%), Positives = 96/235 (40%), Gaps = 17/235 (7%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V V + D N++ P F P + Y + NA VG VI V A D D N + Y
Sbjct: 161 LSDVTTVMVNITDVNEHRPQF-PQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS 219
Query: 499 LQRTSNLTITSPFKINPNTGTVSVAESPILE--GRHALFVEASDQPANPSERRYSLAVVT 556
L + L F I+P G + VA++ E ++L + A+D P +A+
Sbjct: 220 LIGGNQL---GHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQV 276
Query: 557 IEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDA-FEQNDVSYDL-LHGY 614
+V + P P F Y V N IG+ V Q+ ++D +N Y +
Sbjct: 277 ADV-----NDNP--PRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKG 329
Query: 615 EEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQEN-ANLSIVTNATVHVVD 668
G F V G + + LSR + Y + A LS +T+ VHV +
Sbjct: 330 NNGSAFRVTP-DGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTE 383
Score = 54.8 bits (126), Expect = 2e-05
Identities = 50/190 (26%), Positives = 90/190 (47%), Gaps = 19/190 (10%)
Query: 942 ENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFVINERHGHV 1001
EN +G I+ ++A D D LN I Y I ++L +F I+ + G +
Sbjct: 192 ENALVGDVILTVSATDEDGPLNSDITYSL-----IGGNQLG--------HFTIHPKKGEL 238
Query: 1002 IVARSLPPE--SEFRLNISALDGGN--LNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEA 1057
VA++L E S + L + A D G L+++ + + V DVND+ P F + Y+ V+E
Sbjct: 239 QVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQEN 298
Query: 1058 QYTRRVLGKVDATDADFGQNA-NLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKY 1116
+ ++ +D D +N ++ I + F ++P +++ G L R ++ Y
Sbjct: 299 SPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEG-LSRRAQEWY 357
Query: 1117 ILTVVARDNG 1126
L + A D+G
Sbjct: 358 QLQIQASDSG 367
Score = 53.6 bits (123), Expect = 4e-05
Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 7/141 (4%)
Query: 224 DLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNN 283
D G A + Y L + FS+D+ G + LEK L + + L+ L V+AS L
Sbjct: 1 DQGANAQVVYSLPDSAEGH-FSIDATTGVIRLEKPLQVRPQAPLE-----LTVRASDLGT 54
Query: 284 PLKTAQ-ARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEFT 342
P+ + V + ++ L D LP F +++ + E+ P G VLQ+ + E +
Sbjct: 55 PIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYR 114
Query: 343 YQLDDPKGAFSIDPRSGWLTV 363
+ +G F +D R+G L V
Sbjct: 115 VVSGNEQGRFRLDARTGILYV 135
Score = 48.8 bits (111), Expect = 0.001
Identities = 59/225 (26%), Positives = 95/225 (42%), Gaps = 20/225 (8%)
Query: 444 NVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYDLQRTS 503
++ + + D NDN P F N Y +++ N+ +G+ + ++ DPD +NG Y + T
Sbjct: 271 DIAIQVADVNDNPPRFFQLN-YSTTVQENSPIGSKVLQLILSDPDSPENGPP-YSFRITK 328
Query: 504 NLTITSPFKINPNTGTVSVAE--SPILEGRHALFVEASDQPANPSERRYSLAVVTIEVTR 561
S F++ P+ G + AE S + + L ++ASD P SL V + VT
Sbjct: 329 GNN-GSAFRVTPD-GWLVTAEGLSRRAQEWYQLQIQASDSGIPPLS---SLTSVHVHVTE 383
Query: 562 GTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHGYEEGVPFA 621
+ P + VG + G VG+I D Q+ ++Y L G F+
Sbjct: 384 QSHY----APSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFS 439
Query: 622 VEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHV 666
V G I L R + Y F ++ + T A VHV
Sbjct: 440 VGAPDGKIIAAQGLPRGH---YSFNVTV----SDGTFTTTAGVHV 477
>UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 826
Score = 80.2 bits (189), Expect = 4e-13
Identities = 106/432 (24%), Positives = 177/432 (40%), Gaps = 61/432 (14%)
Query: 732 IAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHAT 791
I +G I+ PLDRE +D + + ++ E G + ++ + + D NDN P F
Sbjct: 274 INREGIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPV-ELRVMVGDANDNRPTFPQMQ 332
Query: 792 YEGFIMENSKIGTEIKMDNIIKATDADEGT--NALFMYTLFGEGKEMFDVDENTGVVKFI 849
Y + E + GTEI ++A D D+ N Y L G+ M + N
Sbjct: 333 YHTVVKELATKGTEILT---VQAADNDDPKTDNVRIFYRLVGQ---MPETPRN------- 379
Query: 850 GDSLDREKKIMYKLSLVARDTGGLSSEAELIIMIGDENDNKPEFNQI--EENSKVRIHRE 907
L V RD+G ++ +A+ + P++ E++K R + +
Sbjct: 380 -------------LFRVDRDSGVITVQADSM------EGTAPQYTLTITAEDAKGRHNTD 420
Query: 908 TKLNGTAGFTIIEVKPKNKFALDVDQL--GPLFLIPENIPIGTTIIKLNALDLDS--GLN 963
LN + I++V +N L GP F + E+ +GTT+ ++A D D G +
Sbjct: 421 QWLNSSCT-VIVKVLDENNNPPIFSHLEYGP-FHLAEDSSVGTTVTVVSAWDADEWGGDS 478
Query: 964 GQIRYEFNS----EVY--IPPSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNI 1017
Q+ Y S EV+ + + + AL + + + +++V + P + R
Sbjct: 479 WQVDYRLESGNEEEVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRY 538
Query: 1018 SALDGGNLNDNISVRVFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQN 1077
+V +F+ D+N+ PV ++ Y V E + RV+ + D D +
Sbjct: 539 GPAS------TATVTIFIDDINEG-PVLSQSHYEVTVREGEEPGRVIATIRGYDPD---S 588
Query: 1078 ANLTYFIQPSDTDLPFEISPLTGVLSVNGELDRETEDKYILTVVARDNGXXXXXXXXXXX 1137
+ Y ++ DT F I +G L LDRE Y + VVA D G
Sbjct: 589 HPIRYSLR-GDTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAED-GRNSSLSASTLV 646
Query: 1138 XXXXXDVNDNSP 1149
DVNDNSP
Sbjct: 647 TVHILDVNDNSP 658
Score = 72.1 bits (169), Expect = 1e-10
Identities = 98/364 (26%), Positives = 157/364 (43%), Gaps = 36/364 (9%)
Query: 443 VNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPD--LGQNGMVLYDLQ 500
V + V + DANDN P F P Y +K A GT I V+A D D N + Y L
Sbjct: 312 VELRVMVGDANDNRPTF-PQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLV 370
Query: 501 RTSNLTITSPFKINPNTGTVSVAESPILEG---RHALFVEASDQPANPSERRYSLAVVTI 557
T + F+++ ++G ++V ++ +EG ++ L + A D + ++ + T+
Sbjct: 371 GQMPETPRNLFRVDRDSGVITV-QADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTV 429
Query: 558 EVTRGTKGNKPDIPDFMGAPY-EFWVGSNVGIGTSVGQIRVNDAFEQN----DVSYDLLH 612
V + N P P F Y F + + +GT+V + DA E V Y L
Sbjct: 430 IVKVLDENNNP--PIFSHLEYGPFHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLES 487
Query: 613 GYEEGVPFAVEERSG-----VITVVDDLSRYNRPMYDFEA---VALQENA-NLSIVTNAT 663
G EE V + +R ++ V D R N + A VAL + T
Sbjct: 488 GNEEEVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVT 547
Query: 664 VHVVDVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQ 723
+ + D+N+ G +L +H + V+E G G++ T Y + +R+ +
Sbjct: 548 IFIDDINE--GPVLSQSHYEVT--VRE---GEEPGRVIATIRG--YDPDSHPIRYSLRG- 597
Query: 724 QDVTDDIAIAE-DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDEND 782
D +I + G + T + LDRE+ Y M V+AE + A VT++I D ND
Sbjct: 598 -DTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAEDGRNSSLSASTL-VTVHILDVND 655
Query: 783 NPPV 786
N PV
Sbjct: 656 NSPV 659
Score = 70.9 bits (166), Expect = 2e-10
Identities = 129/499 (25%), Positives = 205/499 (41%), Gaps = 72/499 (14%)
Query: 445 VEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIG----KVKAVDPD---LGQNGMVLY 497
VEV ++D NDN PVF+ E SM+ + ++G + G +V+A+D D +
Sbjct: 103 VEVCVIDKNDNVPVFL-----EESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFS 157
Query: 498 DLQRTSNLTITSPFKINPNTGTVSVAES------PILEGRHALFVEASDQPANPSERRYS 551
L + + + F I+ TG VS+ E P + GR+ L V D A + +S
Sbjct: 158 LLDQIPRIPASHMFSIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQDM-AGKANAFFS 216
Query: 552 LAVVTIEVTRGTKGNKPD---IPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSY 608
V +EVT G PD + + + PY + Q++ + + V Y
Sbjct: 217 TGTVLVEVT-GNAWASPDPVRLQENLPGPYPI----------PISQVK----WSGSPVEY 261
Query: 609 DLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHVV 667
L + E + F + R G+I + L R + + + V + + ++ V V
Sbjct: 262 SLEGEFPEML-FTIN-REGIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVG 319
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRF---LIANQQ 724
D ND R + + + VKE + +I + T NVR L+
Sbjct: 320 DANDNRPTFPQMQYHTV---VKELATKGT--EILTVQAADNDDPKTDNVRIFYRLVGQMP 374
Query: 725 DVTDDI--AIAEDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGA----GIYQVTIYIE 778
+ ++ + G I Q Y +T+ AE KG + V + +
Sbjct: 375 ETPRNLFRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVL 434
Query: 779 DENDNPPVFEHATYEGF-IMENSKIGTEIKMDNIIKATDADE--GTNALFMYTL-FGEGK 834
DEN+NPP+F H Y F + E+S +GT + ++ A DADE G + Y L G +
Sbjct: 435 DENNNPPIFSHLEYGPFHLAEDSSVGTTV---TVVSAWDADEWGGDSWQVDYRLESGNEE 491
Query: 835 EMFDV--DENTGVVKFIGDS-LDREKKIMYKLSLVA-------RDTGGLSSEAELIIMIG 884
E+F + D T I D LD E++ Y L L A R G +S A + I I
Sbjct: 492 EVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVTIFID 551
Query: 885 DENDNKPEFNQIEENSKVR 903
D N+ P +Q VR
Sbjct: 552 DINEG-PVLSQSHYEVTVR 569
Score = 70.5 bits (165), Expect = 3e-10
Identities = 74/288 (25%), Positives = 128/288 (44%), Gaps = 26/288 (9%)
Query: 620 FAVEERSGVITVVDDLSRYNRPMYDFEAVAL----QENANLSIVTNATV--HVVDVNDER 673
F V+ SGVITV D P Y A + N + + ++ TV V+D N+
Sbjct: 381 FRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNP 440
Query: 674 GVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLI--ANQQDVTDDIA 731
+ + P FH+ E+S+ + + +G + V + + N+++V +
Sbjct: 441 PIFSHLEYGP--FHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLN 498
Query: 732 IAE--DGTIFTQKPLDREKRDVYRMTVIAEFNKGVISG----AGIYQVTIYIEDENDNPP 785
+ + + K LD E+ + Y + + A+ ++ G A VTI+I+D N+ P
Sbjct: 499 DRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINEGP- 557
Query: 786 VFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGV 845
V + YE + E + G I I+ D D Y+L G+ K F + + +G
Sbjct: 558 VLSQSHYEVTVREGEEPGRVIAT---IRGYDPDSHP---IRYSLRGDTKRYFSIGKYSGE 611
Query: 846 VKFIGDSLDREKKIMYKLSLVARD--TGGLSSEAELIIMIGDENDNKP 891
+K + +LDRE+ Y + +VA D LS+ + + I D NDN P
Sbjct: 612 LKTV-QALDREENHTYTMEVVAEDGRNSSLSASTLVTVHILDVNDNSP 658
Score = 60.9 bits (141), Expect = 3e-07
Identities = 68/251 (27%), Positives = 106/251 (42%), Gaps = 18/251 (7%)
Query: 436 DEQLMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDL--GQNG 493
D+ L S V V +LD N+N P+F F + ++ VGT + V A D D G +
Sbjct: 420 DQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSSVGTTVTVVSAWDADEWGGDSW 479
Query: 494 MVLYDLQRTSNLTITSPFKINPNTGTVSVAESPILE---GRHALFVEASDQPANPSERRY 550
V Y L+ + + + + T ++ +L+ + V ++ P RY
Sbjct: 480 QVDYRLESGNEEEVFTLLN-DRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRY 538
Query: 551 ---SLAVVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVS 607
S A VTI + +G P + YE V G + IR D + + +
Sbjct: 539 GPASTATVTIFIDDINEG-----PVLSQSHYEVTVREGEEPGRVIATIRGYDP-DSHPIR 592
Query: 608 YDLLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQ-ENANLSIVTNATVHV 666
Y L + F++ + SG + V L R Y E VA N++LS T TVH+
Sbjct: 593 YSLRGDTKR--YFSIGKYSGELKTVQALDREENHTYTMEVVAEDGRNSSLSASTLVTVHI 650
Query: 667 VDVNDERGVLL 677
+DVND VL+
Sbjct: 651 LDVNDNSPVLV 661
Score = 52.4 bits (120), Expect = 9e-05
Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
Query: 734 EDGTIFTQKPLDREKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYE 793
E G ++ KPLDREK+ Y + V F K + + + + V + + D+NDN PVF +
Sbjct: 68 ESGFLYALKPLDREKQPSYSLQV--SFTKSMHTQS--FTVEVCVIDKNDNVPVFLEESMR 123
Query: 794 GFIMENSKIGTEIKMDNIIKATDADE--GTNALFMYTLFGE-----GKEMFDVDENTGVV 846
G + G ++A D D+ +A ++L + MF +D TG V
Sbjct: 124 GSVQLGLLKGIPFMQ---VEALDRDDRNTAHADLRFSLLDQIPRIPASHMFSIDSITGEV 180
Query: 847 KFIGD---SLDREKKIMYKLSLVARDTGG 872
D +LD E YKLS++ +D G
Sbjct: 181 SLTEDGASTLDPEMCGRYKLSVMVQDMAG 209
Score = 52.4 bits (120), Expect = 9e-05
Identities = 99/429 (23%), Positives = 168/429 (39%), Gaps = 56/429 (13%)
Query: 978 PSKLSADALEVKRYFVINERHGHVIVARSLPPESEFRLNISAL----DGGNLNDNISVRV 1033
P + S + + F IN R G + + L E++ + +I + DG + + +RV
Sbjct: 258 PVEYSLEGEFPEMLFTIN-REGIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRV 316
Query: 1034 FVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQ-----PSD 1088
V D ND+ P F + Y+ V+E + V A D D + N+ F + P
Sbjct: 317 MVGDANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVGQMPET 376
Query: 1089 TDLPFEISPLTGVLSVNGELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVND- 1146
F + +GV++V + T +Y LT+ A D G V D
Sbjct: 377 PRNLFRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDE 436
Query: 1147 -NSPKFYAFDELLEWKHPEADELSNHNFESVMMIPVYKA--------TIEENAPIGTTVA 1197
N+P ++ E + E + +V ++ + A ++ G
Sbjct: 437 NNNPPIFSHLEYGPFHLAEDSSVGT----TVTVVSAWDADEWGGDSWQVDYRLESGNE-E 491
Query: 1198 KVFANDTDFIGNGNGLILYSLP--QRKNQQNLGLPSLSSTAILM-----VTVADVPDEV- 1249
+VF D N LIL + +R+N+ L L + + A++ + A V +
Sbjct: 492 EVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVTIFID 551
Query: 1250 EMSDKPVFISRYYELEIEENVNAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVID 1309
++++ PV +YE+ + E P +++ ++ +RY + D +R F I
Sbjct: 552 DINEGPVLSQSHYEVTVREG-EEPGRVIATIRGYDPDSHPIRYSLRG----DTKRYFSIG 606
Query: 1310 PRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDVKVVVR 1369
+G L V++ DRE TY + V VAED V V
Sbjct: 607 KYSGELKTVQALDREENHTYTMEV-----------------VAEDGRNSSLSASTLVTVH 649
Query: 1370 IKDVNDNSP 1378
I DVNDNSP
Sbjct: 650 ILDVNDNSP 658
Score = 48.8 bits (111), Expect = 0.001
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 827 YTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDTGG--LSSEAELIIMIG 884
Y+L GE EM G++ ++ LDRE + + + +V G ++ EL +M+G
Sbjct: 261 YSLEGEFPEMLFTINREGII-YLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVG 319
Query: 885 DENDNKPEFNQIEENSKVRIHRETKLNGTAGFTI 918
D NDN+P F Q++ ++ V +E GT T+
Sbjct: 320 DANDNRPTFPQMQYHTVV---KELATKGTEILTV 350
Score = 47.6 bits (108), Expect = 0.003
Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 14/165 (8%)
Query: 207 RIHKEILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHN 266
R+ + + P PI I Q G+ + Y L LF+++ G ++L LD + +
Sbjct: 236 RLQENLPGPYPI-PISQVKWSGSPVEYSLEGEFPEMLFTINR-EGIIYLNAPLDRETQDQ 293
Query: 267 LQANTFVLQVQASQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVL 326
+ V + ++ P++ + + + D NDN P F Y+ + E G +L
Sbjct: 294 FHIDIVVERPDGREIAKPVE-----LRVMVGDANDNRPTFPQMQYHTVVKELATKGTEIL 348
Query: 327 QVMATDKD--QGENGEFTYQL-----DDPKGAFSIDPRSGWLTVR 364
V A D D + +N Y+L + P+ F +D SG +TV+
Sbjct: 349 TVQAADNDDPKTDNVRIFYRLVGQMPETPRNLFRVDRDSGVITVQ 393
Score = 40.3 bits (90), Expect = 0.40
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 231 LRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQA 290
+RY L G+ ++ FS+ +G L + LD + H T+ ++V A N +A
Sbjct: 591 IRYSL-RGDTKRYFSIGKYSGELKTVQALDREENH-----TYTMEVVAEDGRNSSLSAST 644
Query: 291 RVEIELLDLNDNLPEFEVDF 310
V + +LD+NDN P D+
Sbjct: 645 LVTVHILDVNDNSPVLVGDY 664
Score = 39.5 bits (88), Expect = 0.69
Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 20/160 (12%)
Query: 236 ISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQASQLNNPLKTAQARVEIE 295
++G+D +F ++S G L+ K LD + + + + LQV ++ + T VE+
Sbjct: 57 VNGDDEGIFGVES--GFLYALKPLDREKQPS-----YSLQVSFTK---SMHTQSFTVEVC 106
Query: 296 LLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE--NGEFTYQLDD--PK-- 349
++D NDN+P F + S+ L G +QV A D+D + + + L D P+
Sbjct: 107 VIDKNDNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIP 166
Query: 350 --GAFSIDPRSG--WLTVRNQTVLDREAHSSLRMKVYAKE 385
FSID +G LT + LD E ++ V ++
Sbjct: 167 ASHMFSIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQD 206
>UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1;
Takifugu rubripes|Rep: Cadherin-20 precursor. - Takifugu
rubripes
Length = 878
Score = 79.4 bits (187), Expect = 7e-13
Identities = 73/271 (26%), Positives = 123/271 (45%), Gaps = 19/271 (7%)
Query: 610 LLHGYEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENAN--LSIVTNATVHVV 667
+L G G F +++ +G I + L R + Y A A + L + V +
Sbjct: 49 ILTGEGAGTTFTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTDRPLEPESEFIVKIQ 108
Query: 668 DVNDERGVLLKGAHSPIIFHVKENSAGAAIGQIFHTNMSS-IYGNGTGNVRFLIANQQDV 726
D+ND L G + + + + G ++ Q+ T+ YGN V ++ Q
Sbjct: 109 DINDNEPRFLDGPYWATVPEMSQ--IGTSVIQLTATDADDPTYGNSARVVYSILEGQPYF 166
Query: 727 TDDIAIAEDGTI-FTQKPLDREKRDVYRMTVIAEFNKGVISG-AGIYQVTIYIEDENDNP 784
+ D A+ G + + +DRE R+ Y + + A+ G + G AG V I + D NDNP
Sbjct: 167 SVD---AKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNP 223
Query: 785 PVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNALFMYTLF-GEGKEMFDVDENT 843
P+F+ Y+ I E + +G+ + I A D D G NA Y++ G+G++ FDV +
Sbjct: 224 PMFDQRLYQMSIPEAAPMGSVV---GRIWAKDRDIGINAEMRYSIIDGDGRDTFDVSTDP 280
Query: 844 ----GVVKFIGDSLDREKKIMYKLSLVARDT 870
G++ + LD E K Y L + +T
Sbjct: 281 TNLFGIIT-VKKPLDFETKPSYTLKVEGANT 310
Score = 76.6 bits (180), Expect = 5e-12
Identities = 59/214 (27%), Positives = 95/214 (44%), Gaps = 7/214 (3%)
Query: 686 FHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAEDGTIFTQKPLD 745
F V E G + ++ + S G G++++++ + T G I + LD
Sbjct: 18 FFVLEEYTG--LEPLYIGKLHSDMDKGDGSIKYILTGEGAGTTFTIDDNTGDIHAIQRLD 75
Query: 746 REKRDVYRMTVIAEFNKGVISGAGIYQVTIYIEDENDNPPVFEHATYEGFIMENSKIGTE 805
RE + Y + A + + I+D NDN P F Y + E S+IGT
Sbjct: 76 REMKAQYVLRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQIGTS 135
Query: 806 IKMDNIIKATDADEGTNALFMYTLFGEGKEMFDVDENTGVVKFIGDSLDREKKIMYKLSL 865
+ A D G +A +Y++ EG+ F VD TGV++ +DRE + Y + +
Sbjct: 136 VIQLTATDADDPTYGNSARVVYSIL-EGQPYFSVDAKTGVLRVSLADMDRETRENYSVVI 194
Query: 866 VARD----TGGLSSEAELIIMIGDENDNKPEFNQ 895
A+D GGL+ + I + D NDN P F+Q
Sbjct: 195 QAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQ 228
Score = 66.5 bits (155), Expect = 5e-09
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 26/199 (13%)
Query: 935 GPLFL-IPENIPIGTTIIKLNALDLDSGLNGQIRYEFNSEVYIPPSKLSADALEVKRYFV 993
GP + +PE IGT++I+L A D D G NS +++ LE + YF
Sbjct: 120 GPYWATVPEMSQIGTSVIQLTATDADDPTYG------NS------ARVVYSILEGQPYFS 167
Query: 994 INERHGHVIVARSLPPESEFRLNISAL--------DGGNLNDNISVRVFVKDVNDHFPVF 1045
++ + G + V+ + + E R N S + G L +V + + D+ND+ P+F
Sbjct: 168 VDAKTGVLRVSLA-DMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMF 226
Query: 1046 KKTWYNFNVEEAQYTRRVLGKVDATDADFGQNANLTYFIQPSDTDLPFEISP----LTGV 1101
+ Y ++ EA V+G++ A D D G NA + Y I D F++S L G+
Sbjct: 227 DQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDGDGRDTFDVSTDPTNLFGI 286
Query: 1102 LSVNGELDRETEDKYILTV 1120
++V LD ET+ Y L V
Sbjct: 287 ITVKKPLDFETKPSYTLKV 305
Score = 60.1 bits (139), Expect = 5e-07
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 12/173 (6%)
Query: 220 AIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQANTFVLQVQAS 279
A D G A + Y ++ G + FS+D+ G L + D+D E + + +QA
Sbjct: 144 ADDPTYGNSARVVYSILEG--QPYFSVDAKTGVLRVSLA-DMDRETR---ENYSVVIQAK 197
Query: 280 QLNNPLK--TAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGE 337
+ + V I L D+NDN P F+ Y +SI E P G V ++ A D+D G
Sbjct: 198 DMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGI 257
Query: 338 NGEFTYQLDDPKGA----FSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
N E Y + D G S DP + + + + LD E S +KV T
Sbjct: 258 NAEMRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANT 310
Score = 58.4 bits (135), Expect = 1e-06
Identities = 49/186 (26%), Positives = 90/186 (48%), Gaps = 12/186 (6%)
Query: 211 EILFPEPIHAIDQDLGVGATLRYELISGNDRKLFSLDSVNGSLFLEKELDLDAEHNLQAN 270
E L+ +H+ D D G G+ ++Y L F++D G + + LD + +
Sbjct: 28 EPLYIGKLHS-DMDKGDGS-IKYILTGEGAGTTFTIDDNTGDIHAIQRLDREMKAQ---- 81
Query: 271 TFVLQVQA-SQLNNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVM 329
+VL+ QA ++L + ++ +++ D+NDN P F Y ++ E G SV+Q+
Sbjct: 82 -YVLRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLT 140
Query: 330 ATDKDQ---GENGEFTYQLDDPKGAFSIDPRSGWLTVRNQTVLDREAHSSLRMKVYAKET 386
ATD D G + Y + + + FS+D ++G L V + +DRE + + + AK+
Sbjct: 141 ATDADDPTYGNSARVVYSILEGQPYFSVDAKTGVLRV-SLADMDRETRENYSVVIQAKDM 199
Query: 387 NPSVVG 392
+ G
Sbjct: 200 GGQMGG 205
Score = 54.8 bits (126), Expect = 2e-05
Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 1033 VFVKDVNDHFPVFKKTWYNFNVEEAQYTRRVLGKVDATDAD---FGQNANLTYFIQPSDT 1089
V ++D+ND+ P F Y V E + ++ ATDAD +G +A + Y I
Sbjct: 105 VKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSILEGQP 164
Query: 1090 DLPFEISPLTGVLSVN-GELDRETEDKYILTVVARD-NGXXXXXXXXXXXXXXXXDVNDN 1147
F + TGVL V+ ++DRET + Y + + A+D G D+NDN
Sbjct: 165 Y--FSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDN 222
Query: 1148 SPKFYAFDELLEWKHPEA 1165
P F L + PEA
Sbjct: 223 PPMF--DQRLYQMSIPEA 238
Score = 53.6 bits (123), Expect = 4e-05
Identities = 68/267 (25%), Positives = 118/267 (44%), Gaps = 19/267 (7%)
Query: 571 PDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQN-DVSYDLLHGYEEGVP-FAVEERSGV 628
P F+ PY V IGTSV Q+ DA + S +++ EG P F+V+ ++GV
Sbjct: 115 PRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSILEGQPYFSVDAKTGV 174
Query: 629 ITV-VDDLSRYNRPMYDFEAVALQ---ENANLSIVTNATVHVVDVNDERGVLLKGAHSPI 684
+ V + D+ R R Y A + L+ T + + D+ND + + +
Sbjct: 175 LRVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLYQMS 234
Query: 685 IFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDIAIAED--GTIFTQK 742
I + G+ +G+I+ + I N + + +D D + G I +K
Sbjct: 235 I--PEAAPMGSVVGRIWAKDRD-IGINAEMRYSIIDGDGRDTFDVSTDPTNLFGIITVKK 291
Query: 743 PLDREKRDVYRMTVIAEFNK--GVISGAGIYQ-VTI-YIEDEN-DNPPVFEHATYEGFIM 797
PLD E + Y + V + + G ++ VTI ++ E+ D PP+F+ Y +
Sbjct: 292 PLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTIVHVSVEDVDEPPLFDSPGYYIELP 351
Query: 798 ENSKIGTEIKMDNIIKATDADEGTNAL 824
E+++IGT +K + A D D N +
Sbjct: 352 EDAEIGTVVK---TVSARDPDSANNTV 375
Score = 53.2 bits (122), Expect = 5e-05
Identities = 102/471 (21%), Positives = 183/471 (38%), Gaps = 54/471 (11%)
Query: 439 LMSFVNVEVTLLDANDNNPVFVPSNLYEFSMKSNAKVGTVIGKVKAVDPDLGQNGMVLYD 498
L V +TL D NDN P+F LY+ S+ A +G+V+G++ A D D+G N + Y
Sbjct: 206 LAGTTTVNITLTDINDNPPMF-DQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYS 264
Query: 499 LQRTSNLTITSPFKINPNT--GTVSVAESPILEGR--HALFVEASDQPANPSERRYS-LA 553
+ T +P G ++V + E + + L VE ++ +P +
Sbjct: 265 IIDGDGRD-TFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFK 323
Query: 554 VVTIEVTRGTKGNKPDIPDFMGAPYEFWVGSNVGIGTSVGQIRVNDAFEQNDVSYDLLHG 613
VTI ++P + D G Y + + IGT V + D N+ +
Sbjct: 324 DVTIVHVSVEDVDEPPLFDSPG--YYIELPEDAEIGTVVKTVSARDPDSANNT---VRSP 378
Query: 614 YEEGVPFAVEERSGVITVVDDLSRYNRPMYDFEAVALQENANLSIVTNATVHVVDVNDER 673
++ + +R V + L+ Y R V L + ++ + + ++
Sbjct: 379 PQDVINCYTTQRLKVKERLVTLTGYTRAEMVNGLVVLGLGGGVVLIKTINDYALRLSLRL 438
Query: 674 GVLL---KGAHSPIIFHVKENSAGAAIGQIFHTNMSSIYGNGTGNVRFLIANQQDVTDDI 730
++ + A + + N GA + + G R+ I D+
Sbjct: 439 SIIWGVGQQAAASLSGFTSWNRDGAGGWEALMNGCMCCF----GVCRYSIERTNDLDKYF 494
Query: 731 AI-AEDGTIFTQKPLDREKRDVYRMTVIA-EFNKG------VISGAGIYQVTIYIEDE-- 780
I G + T + LDRE+ + +TV+A E G SG+ + +V + + +
Sbjct: 495 YIDITSGALMTVRTLDREEMSWHNITVLAMEMRLGPGKWTLAPSGSLVIRVCVCVSTDNP 554
Query: 781 ---------------NDNPPVFEHATYEGFIMENSKIGTEIKMDNIIKATDADEGTNAL- 824
NDNPP H E ++ EN+K G I+M + A D DE
Sbjct: 555 SQIASVSVAIKITDVNDNPPSLTH-YLEAYVCENAKAGQLIQM---VTAVDVDEPQGGQH 610
Query: 825 FMYTLFGEGKE-----MFDVDENTGVVKFIGDSLDREKKIMYKLSLVARDT 870
F Y+L E + D +NT V ++++ ++ L ++ D+
Sbjct: 611 FYYSLAPEAANNPNFTLRDNQDNTAWVLTRRGGWSQQQQTVFHLPIIISDS 661
Score = 48.4 bits (110), Expect = 0.002
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 18/115 (15%)
Query: 1305 TFVIDPRNGTLYLVRSPDREVKDTYEVIVRAERQKYSRELPHMIYPVAEDVLEGMTKYDV 1364
TF ID G ++ ++ DRE+K Y ++RA+ + + P LE +++
Sbjct: 58 TFTIDDNTGDIHAIQRLDREMKAQY--VLRAQARNRLTDRP----------LEPESEF-- 103
Query: 1365 KVVVRIKDVNDNSPKFTNGNRPLVTAIPTTAPFGYQVMQLKGAIGHHPTASRTVR 1419
+V+I+D+NDN P+F +G P +P + G V+QL PT + R
Sbjct: 104 --IVKIQDINDNEPRFLDG--PYWATVPEMSQIGTSVIQLTATDADDPTYGNSAR 154
Score = 45.6 bits (103), Expect = 0.011
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 9/128 (7%)
Query: 218 IHAIDQDLGVGATLRYELISGNDRKLF--SLDSVN--GSLFLEKELDLDAEHNLQANTFV 273
I A D+D+G+ A +RY +I G+ R F S D N G + ++K LD + + +
Sbjct: 248 IWAKDRDIGINAEMRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEG 307
Query: 274 LQVQASQL---NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMA 330
Q L + P K V + + D+ D P F+ Y I + E+ G V V A
Sbjct: 308 ANTQVDPLFHHHGPFKDVTI-VHVSVEDV-DEPPLFDSPGYYIELPEDAEIGTVVKTVSA 365
Query: 331 TDKDQGEN 338
D D N
Sbjct: 366 RDPDSANN 373
Score = 42.3 bits (95), Expect = 0.099
Identities = 73/307 (23%), Positives = 123/307 (40%), Gaps = 38/307 (12%)
Query: 1049 WYNFNVEEAQYTRR---VLGKVDATDADFGQNANLTYFIQPSDTDLPFEISPLTGVLSVN 1105
W F V E +YT +GK+ + D D G + ++ Y + F I TG +
Sbjct: 15 WNQFFVLE-EYTGLEPLYIGKLHS-DMDKG-DGSIKYILTGEGAGTTFTIDDNTGDIHAI 71
Query: 1106 GELDRETEDKYILTVVARDNGXXXXXXXXXXXXXXXXDVNDNSPKF-------------Y 1152
LDRE + +Y+L AR+ D+NDN P+F
Sbjct: 72 QRLDREMKAQYVLRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQ 131
Query: 1153 AFDELLEWKHPEADELSNHNFESVMMIPVYKATIEENAPIGTTVAKVFANDTDFIGNGNG 1212
+++ +AD+ + N V + + + + T V +V D D N
Sbjct: 132 IGTSVIQLTATDADDPTYGNSARV-VYSILEGQPYFSVDAKTGVLRVSLADMDRETREN- 189
Query: 1213 LILYSLPQRKNQQNLGLPSLSSTAILMVTVADVPDEVEMSDKPVFISRYYELEIEE--NV 1270
YS+ + + L+ T + +T+ D+ D + P+F R Y++ I E +
Sbjct: 190 ---YSVVIQAKDMGGQMGGLAGTTTVNITLTDIND-----NPPMFDQRLYQMSIPEAAPM 241
Query: 1271 NAPVELVSLNLTEHYENFKMRYYILNENDTDIRRTFVI--DPRN--GTLYLVRSPDREVK 1326
+ V + + N +MRY I+ D D R TF + DP N G + + + D E K
Sbjct: 242 GSVVGRIWAKDRDIGINAEMRYSII---DGDGRDTFDVSTDPTNLFGIITVKKPLDFETK 298
Query: 1327 DTYEVIV 1333
+Y + V
Sbjct: 299 PSYTLKV 305
Score = 38.3 bits (85), Expect = 1.6
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Query: 282 NNPLKTAQARVEIELLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVMATDKDQGENGEF 341
+NP + A V I++ D+NDN P + + EN G + V A D D+ + G+
Sbjct: 552 DNPSQIASVSVAIKITDVNDNPPSL-THYLEAYVCENAKAGQLIQMVTAVDVDEPQGGQH 610
Query: 342 TYQLDDPKGA 351
Y P+ A
Sbjct: 611 FYYSLAPEAA 620
Score = 37.5 bits (83), Expect = 2.8
Identities = 16/29 (55%), Positives = 20/29 (68%)
Query: 85 VYIEDVNDNVPIFLDTPYHVTVDELTPTG 113
V I+D+NDN P FLD PY TV E++ G
Sbjct: 105 VKIQDINDNEPRFLDGPYWATVPEMSQIG 133
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.136 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,715,263,853
Number of Sequences: 1657284
Number of extensions: 79056993
Number of successful extensions: 209028
Number of sequences better than 10.0: 491
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 177989
Number of HSP's gapped (non-prelim): 18767
length of query: 1518
length of database: 575,637,011
effective HSP length: 111
effective length of query: 1407
effective length of database: 391,678,487
effective search space: 551091631209
effective search space used: 551091631209
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 79 (35.9 bits)
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