Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002723-TA|BGIBMGA002723-PA|IPR004156|Organic anion
transporter polypeptide OATP, IPR011497|Protease inhibitor, Kazal-type
(411 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF205075-1|AAG42207.1| 848|Homo sapiens organic anion transport... 154 5e-37
BC000585-1|AAH00585.1| 692|Homo sapiens SLCO3A1 protein protein. 140 8e-33
AF205074-1|AAG42206.1| 710|Homo sapiens organic anion transport... 140 8e-33
AF187816-1|AAG43446.1| 710|Homo sapiens PGE1 transporter protein. 140 8e-33
AB031050-1|BAA89287.1| 710|Homo sapiens organic anion transport... 140 8e-33
U21943-1|AAA87732.1| 670|Homo sapiens organic anion transportin... 138 2e-32
AJ400735-1|CAB97006.1| 670|Homo sapiens organic anion transport... 138 2e-32
AF279784-1|AAG30037.1| 670|Homo sapiens organic anion transport... 138 2e-32
BC139755-1|AAI39756.1| 793|Homo sapiens SLCO5A1 protein protein. 137 6e-32
BC114376-1|AAI14377.1| 691|Homo sapiens solute carrier organic ... 131 5e-30
AY945934-1|AAX20114.1| 691|Homo sapiens solute carrier organic ... 131 5e-30
AJ400749-1|CAB97007.1| 691|Homo sapiens organic anion transport... 131 5e-30
AJ132573-1|CAB62577.1| 691|Homo sapiens organic anion transport... 131 5e-30
AF205071-1|AAF20212.1| 691|Homo sapiens organic anion transport... 131 5e-30
AF060500-1|AAD38323.1| 691|Homo sapiens liver specific transpor... 131 5e-30
AB026257-1|BAA78639.1| 691|Homo sapiens organic anion transport... 131 5e-30
BC034976-1|AAH34976.1| 657|Homo sapiens SLCO6A1 protein protein. 128 3e-29
AY273897-1|AAP33048.1| 719|Homo sapiens OATP-I protein. 128 3e-29
AF505657-1|AAP30851.1| 719|Homo sapiens organic anion transport... 128 3e-29
AY342017-1|AAQ19672.1| 702|Homo sapiens organic anion transport... 128 4e-29
AK128854-1|BAC87647.1| 724|Homo sapiens 12 (SLC21A12). protein. 128 4e-29
AJ400763-1|CAB97008.1| 702|Homo sapiens organic anion transport... 128 4e-29
AJ251506-1|CAB96997.1| 702|Homo sapiens organic anion transport... 128 4e-29
AF401643-1|AAQ03086.1| 724|Homo sapiens organic anion transport... 128 4e-29
AF187815-1|AAG43445.1| 702|Homo sapiens liver-specific organic ... 128 4e-29
BC022461-1|AAH22461.1| 712|Homo sapiens solute carrier organic ... 126 1e-28
AY273896-1|AAP33047.2| 724|Homo sapiens OATP-H protein. 126 1e-28
AF260704-1|AAF70338.1| 712|Homo sapiens organic anion transport... 126 1e-28
AF205076-1|AAG42208.1| 712|Homo sapiens organic anion transport... 126 1e-28
U70867-1|AAC09469.1| 643|Homo sapiens prostaglandin transporter... 122 2e-27
BC051347-1|AAH51347.1| 643|Homo sapiens solute carrier organic ... 122 2e-27
BC041140-1|AAH41140.2| 643|Homo sapiens solute carrier organic ... 122 2e-27
AF056732-1|AAC62004.1| 643|Homo sapiens prostaglandin transport... 122 2e-27
AY442325-1|AAS01767.1| 687|Homo sapiens organic anion transport... 118 5e-26
AY257470-1|AAP81211.1| 687|Homo sapiens liver-specific organic ... 118 5e-26
AF401642-1|AAQ03085.1| 640|Homo sapiens liver-specific organic ... 118 5e-26
AY442326-1|AAS01768.1| 748|Homo sapiens organic anion transport... 116 2e-25
AY257471-1|AAP81212.1| 748|Homo sapiens liver-specific organic ... 116 2e-25
BC015727-1|AAH15727.1| 722|Homo sapiens solute carrier organic ... 109 2e-23
AL357033-2|CAC14920.1| 722|Homo sapiens solute carrier organic ... 109 2e-23
AF205072-1|AAG42204.1| 722|Homo sapiens organic anion transport... 109 2e-23
AF187817-1|AAG43447.1| 722|Homo sapiens colon organic anion tra... 109 2e-23
AB031051-1|BAA89288.1| 722|Homo sapiens organic anion transport... 109 2e-23
AK131445-1|BAD18590.1| 466|Homo sapiens protein ( Homo sapiens ... 103 2e-21
AK023410-1|BAB14566.1| 583|Homo sapiens protein ( Homo sapiens ... 101 5e-21
BC041095-1|AAH41095.1| 709|Homo sapiens solute carrier organic ... 95 5e-19
AF205073-1|AAG42205.1| 687|Homo sapiens organic anion transport... 95 5e-19
AB026256-1|BAA78638.1| 709|Homo sapiens organic anion transport... 95 5e-19
AB020687-1|BAA74903.2| 727|Homo sapiens KIAA0880 protein protein. 95 5e-19
AF085224-1|AAD52694.1| 579|Homo sapiens brain organic anion tra... 86 2e-16
AF104334-1|AAF15545.1| 661|Homo sapiens putative organic anion ... 56 2e-07
AL357033-3|CAC14921.1| 151|Homo sapiens solute carrier organic ... 51 6e-06
AK000551-1|BAA91247.1| 124|Homo sapiens protein ( Homo sapiens ... 51 6e-06
BC042452-1|AAH42452.2| 408|Homo sapiens SLCO1A2 protein protein. 43 0.002
D50406-1|BAA34060.1| 971|Homo sapiens ST15 protein. 38 0.065
AL158830-3|CAD13384.2| 971|Homo sapiens reversion-inducing-cyst... 38 0.065
AL138834-5|CAH70155.1| 971|Homo sapiens reversion-inducing-cyst... 38 0.065
BC131613-1|AAI31614.1| 292|Homo sapiens keratin associated prot... 36 0.26
AB076356-1|BAD01543.1| 292|Homo sapiens keratin associated prot... 36 0.26
X83961-1|CAA58791.1| 380|Homo sapiens transmembrane protein pro... 36 0.34
U19878-1|AAA64622.1| 380|Homo sapiens transmembrane protein pro... 36 0.34
BC035056-1|AAH35056.1| 380|Homo sapiens transmembrane protein w... 36 0.34
AL354917-2|CAI16192.1| 380|Homo sapiens transmembrane protein w... 36 0.34
AL353805-7|CAI12543.1| 380|Homo sapiens transmembrane protein w... 36 0.34
BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein. 33 1.8
AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein. 33 1.8
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 33 1.8
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 33 1.8
S44195-1|AAB23327.1| 62|Homo sapiens agrin protein. 33 2.4
D87465-1|BAA13404.2| 510|Homo sapiens KIAA0275 protein. 33 2.4
BC023558-1|AAH23558.1| 424|Homo sapiens SPOCK2 protein protein. 33 2.4
AY358921-1|AAQ89280.1| 424|Homo sapiens SPOCK2 protein. 33 2.4
AJ001453-1|CAA04774.1| 424|Homo sapiens testican-2 protein. 33 2.4
BC022367-1|AAH22367.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 31 5.6
AL590733-2|CAH71125.1| 292|Homo sapiens R-spondin 3 homolog (Xe... 31 5.6
AL590733-1|CAH71124.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 31 5.6
AL031776-2|CAI20142.1| 292|Homo sapiens R-spondin 3 homolog (Xe... 31 5.6
AL031776-1|CAI20141.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 31 5.6
AK027346-1|BAB55051.1| 292|Homo sapiens protein ( Homo sapiens ... 31 5.6
AF251057-1|AAK34947.1| 272|Homo sapiens thrombospondin protein. 31 5.6
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 31 9.8
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 31 9.8
CR541813-1|CAG46612.1| 317|Homo sapiens FST protein. 31 9.8
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 31 9.8
AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein. 31 9.8
>AF205075-1|AAG42207.1| 848|Homo sapiens organic anion transporter
polypeptide-related protein 4 protein.
Length = 848
Score = 154 bits (374), Expect = 5e-37
Identities = 87/340 (25%), Positives = 147/340 (43%), Gaps = 14/340 (4%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V+D A R ++N ++ + S ++ +F+PK++E QF +P +A++ +
Sbjct: 418 VRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVI 477
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLS-- 159
G +I KL AR+ + L V C + ++
Sbjct: 478 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIP 537
Query: 160 --AASDSALP-------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
+P C++ C C+ + PVCG D TY +PC AGC+ S L
Sbjct: 538 YTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRN 597
Query: 211 YYNCSCINGSATTD---LGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAA 267
Y C+C+ +G+ L + GYAVSG+C C+ + F+
Sbjct: 598 YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFI 657
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRD 327
+ F+ A + A+++ +R + ++ A+G+ + +P PI FGA +D C L
Sbjct: 658 VTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ 717
Query: 328 YACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLVW 367
CG G+C Y+ SFR+ Y GL+A + F+ FI L W
Sbjct: 718 QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAW 757
>BC000585-1|AAH00585.1| 692|Homo sapiens SLCO3A1 protein protein.
Length = 692
Score = 140 bits (339), Expect = 8e-33
Identities = 95/330 (28%), Positives = 151/330 (45%), Gaps = 39/330 (11%)
Query: 50 KRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXX 109
K ++N + ++ + + ++G +FL KYLE+QF L T AN +
Sbjct: 343 KHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLG 402
Query: 110 XXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL------SAASD 163
G+++ KL SA + +A V+ +F+ C + S A
Sbjct: 403 IFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPG 462
Query: 164 SAL----PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCING 219
SAL PC+ C C+ SF+PVCG D TYLS C AGC N+T L C+C+
Sbjct: 463 SALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-------NSTNLT-GCACL-- 512
Query: 220 SATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVP-CSQIYV-FIAIFAAIMFVHASGEV 277
TT + A V G+C P C + ++ F+ + + A +
Sbjct: 513 --TT---------------VPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQT 555
Query: 278 GAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACV 337
+V+++IR K+ A+GV+ + + G +P P++FGA +D+ C CGE GACV
Sbjct: 556 PSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACV 615
Query: 338 FYDTHSFRYFYLGLSAAIMFLAFIMDLLVW 367
YD +RY Y+ ++ A+ AFI+ W
Sbjct: 616 LYDNVVYRYLYVSIAIALKSFAFILYTTTW 645
>AF205074-1|AAG42206.1| 710|Homo sapiens organic anion transporter
polypeptide-related protein 3 protein.
Length = 710
Score = 140 bits (339), Expect = 8e-33
Identities = 95/330 (28%), Positives = 151/330 (45%), Gaps = 39/330 (11%)
Query: 50 KRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXX 109
K ++N + ++ + + ++G +FL KYLE+QF L T AN +
Sbjct: 343 KHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLG 402
Query: 110 XXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL------SAASD 163
G+++ KL SA + +A V+ +F+ C + S A
Sbjct: 403 IFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPG 462
Query: 164 SAL----PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCING 219
SAL PC+ C C+ SF+PVCG D TYLS C AGC N+T L C+C+
Sbjct: 463 SALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-------NSTNLT-GCACL-- 512
Query: 220 SATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVP-CSQIYV-FIAIFAAIMFVHASGEV 277
TT + A V G+C P C + ++ F+ + + A +
Sbjct: 513 --TT---------------VPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQT 555
Query: 278 GAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACV 337
+V+++IR K+ A+GV+ + + G +P P++FGA +D+ C CGE GACV
Sbjct: 556 PSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACV 615
Query: 338 FYDTHSFRYFYLGLSAAIMFLAFIMDLLVW 367
YD +RY Y+ ++ A+ AFI+ W
Sbjct: 616 LYDNVVYRYLYVSIAIALKSFAFILYTTTW 645
>AF187816-1|AAG43446.1| 710|Homo sapiens PGE1 transporter protein.
Length = 710
Score = 140 bits (339), Expect = 8e-33
Identities = 95/330 (28%), Positives = 151/330 (45%), Gaps = 39/330 (11%)
Query: 50 KRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXX 109
K ++N + ++ + + ++G +FL KYLE+QF L T AN +
Sbjct: 343 KHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLG 402
Query: 110 XXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL------SAASD 163
G+++ KL SA + +A V+ +F+ C + S A
Sbjct: 403 IFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPG 462
Query: 164 SAL----PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCING 219
SAL PC+ C C+ SF+PVCG D TYLS C AGC N+T L C+C+
Sbjct: 463 SALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-------NSTNLT-GCACL-- 512
Query: 220 SATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVP-CSQIYV-FIAIFAAIMFVHASGEV 277
TT + A V G+C P C + ++ F+ + + A +
Sbjct: 513 --TT---------------VPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQT 555
Query: 278 GAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACV 337
+V+++IR K+ A+GV+ + + G +P P++FGA +D+ C CGE GACV
Sbjct: 556 PSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACV 615
Query: 338 FYDTHSFRYFYLGLSAAIMFLAFIMDLLVW 367
YD +RY Y+ ++ A+ AFI+ W
Sbjct: 616 LYDNVVYRYLYVSIAIALKSFAFILYTTTW 645
>AB031050-1|BAA89287.1| 710|Homo sapiens organic anion transporter
OATP-D protein.
Length = 710
Score = 140 bits (339), Expect = 8e-33
Identities = 95/330 (28%), Positives = 151/330 (45%), Gaps = 39/330 (11%)
Query: 50 KRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXX 109
K ++N + ++ + + ++G +FL KYLE+QF L T AN +
Sbjct: 343 KHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLG 402
Query: 110 XXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL------SAASD 163
G+++ KL SA + +A V+ +F+ C + S A
Sbjct: 403 IFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPG 462
Query: 164 SAL----PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCING 219
SAL PC+ C C+ SF+PVCG D TYLS C AGC N+T L C+C+
Sbjct: 463 SALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-------NSTNLT-GCACL-- 512
Query: 220 SATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVP-CSQIYV-FIAIFAAIMFVHASGEV 277
TT + A V G+C P C + ++ F+ + + A +
Sbjct: 513 --TT---------------VPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQT 555
Query: 278 GAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACV 337
+V+++IR K+ A+GV+ + + G +P P++FGA +D+ C CGE GACV
Sbjct: 556 PSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACV 615
Query: 338 FYDTHSFRYFYLGLSAAIMFLAFIMDLLVW 367
YD +RY Y+ ++ A+ AFI+ W
Sbjct: 616 LYDNVVYRYLYVSIAIALKSFAFILYTTTW 645
>U21943-1|AAA87732.1| 670|Homo sapiens organic anion transporting
polypeptide protein.
Length = 670
Score = 138 bits (335), Expect = 2e-32
Identities = 97/360 (26%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 22 IKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPK 81
IK E Q ++ K+++ KDF +K N I M SV+ + SF+PK
Sbjct: 282 IKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPK 341
Query: 82 YLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAG 141
YLE+Q+ + + DA + G+++ K + +Q +
Sbjct: 342 YLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLL 401
Query: 142 MVALMFVSCPEKSY-----------RYLSAASDSALPCSMACHCENASFSPVCGQDSYTY 190
++C S + L +D C++ C+C + + PVCG + +Y
Sbjct: 402 YFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSY 461
Query: 191 LSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGE 250
LS C AGC S+ N ++ NCSCI S + AV G
Sbjct: 462 LSACLAGCETSIGTGIN-MVFQNCSCIQTSGNSS---------------------AVLGL 499
Query: 251 C--GVPCSQIYVFIAIFAAIM-FVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFG 307
C G CS + + I +A+ F+++ + ++++RC +K++ +G+ F VF
Sbjct: 500 CDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFA 559
Query: 308 NVPCPIVFGAAVDAAC-RLRDYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
+P PI FGA +D+ C CGE GAC YD+ +FRY YLGL AA+ +F+ L++
Sbjct: 560 GIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALII 619
>AJ400735-1|CAB97006.1| 670|Homo sapiens organic anion transporting
polypeptide 1 (OATP1) protein.
Length = 670
Score = 138 bits (335), Expect = 2e-32
Identities = 97/360 (26%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 22 IKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPK 81
IK E Q ++ K+++ KDF +K N I M SV+ + SF+PK
Sbjct: 282 IKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPK 341
Query: 82 YLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAG 141
YLE+Q+ + + DA + G+++ K + +Q +
Sbjct: 342 YLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLL 401
Query: 142 MVALMFVSCPEKSY-----------RYLSAASDSALPCSMACHCENASFSPVCGQDSYTY 190
++C S + L +D C++ C+C + + PVCG + +Y
Sbjct: 402 YFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSY 461
Query: 191 LSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGE 250
LS C AGC S+ N ++ NCSCI S + AV G
Sbjct: 462 LSACLAGCETSIGTGIN-MVFQNCSCIQTSGNSS---------------------AVLGL 499
Query: 251 C--GVPCSQIYVFIAIFAAIM-FVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFG 307
C G CS + + I +A+ F+++ + ++++RC +K++ +G+ F VF
Sbjct: 500 CDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFA 559
Query: 308 NVPCPIVFGAAVDAAC-RLRDYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
+P PI FGA +D+ C CGE GAC YD+ +FRY YLGL AA+ +F+ L++
Sbjct: 560 GIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALII 619
>AF279784-1|AAG30037.1| 670|Homo sapiens organic anion transporting
polypeptide protein.
Length = 670
Score = 138 bits (335), Expect = 2e-32
Identities = 97/360 (26%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 22 IKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPK 81
IK E Q ++ K+++ KDF +K N I M SV+ + SF+PK
Sbjct: 282 IKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPK 341
Query: 82 YLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAG 141
YLE+Q+ + + DA + G+++ K + +Q +
Sbjct: 342 YLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLL 401
Query: 142 MVALMFVSCPEKSY-----------RYLSAASDSALPCSMACHCENASFSPVCGQDSYTY 190
++C S + L +D C++ C+C + + PVCG + +Y
Sbjct: 402 YFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSY 461
Query: 191 LSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGE 250
LS C AGC S+ N ++ NCSCI S + AV G
Sbjct: 462 LSACLAGCETSIGTGIN-MVFQNCSCIQTSGNSS---------------------AVLGL 499
Query: 251 C--GVPCSQIYVFIAIFAAIM-FVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFG 307
C G CS + + I +A+ F+++ + ++++RC +K++ +G+ F VF
Sbjct: 500 CDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFA 559
Query: 308 NVPCPIVFGAAVDAAC-RLRDYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
+P PI FGA +D+ C CGE GAC YD+ +FRY YLGL AA+ +F+ L++
Sbjct: 560 GIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALII 619
>BC139755-1|AAI39756.1| 793|Homo sapiens SLCO5A1 protein protein.
Length = 793
Score = 137 bits (332), Expect = 6e-32
Identities = 63/203 (31%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 168 CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTD--- 224
C++ C C+ + PVCG D TY +PC AGC+ S L Y C+C+
Sbjct: 500 CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPT 559
Query: 225 LGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLII 284
+G+ L + GYAVSG+C C+ + F+ + F+ A + A+++ +
Sbjct: 560 VGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTL 619
Query: 285 RCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF 344
R + ++ A+G+ + +P PI FGA +D C L CG G+C Y+ SF
Sbjct: 620 RSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSF 679
Query: 345 RYFYLGLSAAIMFLAFIMDLLVW 367
R+ Y GL+A + F+ FI L W
Sbjct: 680 RFVYFGLAAGLKFVGFIFIFLAW 702
>BC114376-1|AAI14377.1| 691|Homo sapiens solute carrier organic
anion transporter family, member 1B1 protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AY945934-1|AAX20114.1| 691|Homo sapiens solute carrier organic
anion transporter family, member 1B1 protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AJ400749-1|CAB97007.1| 691|Homo sapiens organic anion transporting
polypeptide 2 (OATP2) protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AJ132573-1|CAB62577.1| 691|Homo sapiens organic anion transporting
polypeptide 2 protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AF205071-1|AAF20212.1| 691|Homo sapiens organic anion transport
polypeptide 2 protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AF060500-1|AAD38323.1| 691|Homo sapiens liver specific transporter
protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>AB026257-1|BAA78639.1| 691|Homo sapiens organic anion transporter
OATP-C protein.
Length = 691
Score = 131 bits (316), Expect = 5e-30
Identities = 88/340 (25%), Positives = 151/340 (44%), Gaps = 33/340 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF + K +TN + + ++L + G ++++ KY+E+Q+ P+ AN++
Sbjct: 322 VTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVI 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
G +I K + + + + + F+ C KS L+
Sbjct: 382 TIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMT 441
Query: 162 SDSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
D P C+ C+C+ + + PVCG + TY+SPC AGC S + +
Sbjct: 442 YDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG-NKKPIV 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + Y F+AI
Sbjct: 501 FYNCSCL---------EVTGLQNRNYS--------AHLGECPRDDACTRKFYFFVAIQVL 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
+F A G V+LI++ K++A+G I G + PI FGA +D C +
Sbjct: 544 NLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
CG G+C Y++ SF YLGLS+ + + ++ +++
Sbjct: 604 TNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIIL 643
>BC034976-1|AAH34976.1| 657|Homo sapiens SLCO6A1 protein protein.
Length = 657
Score = 128 bits (310), Expect = 3e-29
Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 28/321 (8%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
+KD AA+ + N +L+ S + I G FLP YLE QF L A ++
Sbjct: 307 IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLV 366
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
GV++ L S + + I +V ++FV C + ++
Sbjct: 367 LIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINED 426
Query: 162 SDSA-------LPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
D PC+ C C ++ +S +CG+D Y SPC AGC S + N +YYNC
Sbjct: 427 YDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNC 485
Query: 215 SCI-NGSATTDL-GKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIA-IFAAIMFV 271
SCI G T D G D A P G+C C ++ +FIA IF+ ++F
Sbjct: 486 SCIKEGLITADAEGDFID---------ARP------GKCDAKCYKLPLFIAFIFSTLIFS 530
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
SG V VL + R +++A+GV + +FG +P P +F + + +C LRD C
Sbjct: 531 GFSG-VPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKC 589
Query: 331 GELGACVFYDTHSFRYFYLGL 351
G G C Y+ + +G+
Sbjct: 590 GHTGRCWIYNKTKMAFLLVGI 610
>AY273897-1|AAP33048.1| 719|Homo sapiens OATP-I protein.
Length = 719
Score = 128 bits (310), Expect = 3e-29
Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 28/321 (8%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
+KD AA+ + N +L+ S + I G FLP YLE QF L A ++
Sbjct: 369 IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLV 428
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
GV++ L S + + I +V ++FV C + ++
Sbjct: 429 LIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINED 488
Query: 162 SDSA-------LPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
D PC+ C C ++ +S +CG+D Y SPC AGC S + N +YYNC
Sbjct: 489 YDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNC 547
Query: 215 SCI-NGSATTDL-GKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIA-IFAAIMFV 271
SCI G T D G D A P G+C C ++ +FIA IF+ ++F
Sbjct: 548 SCIKEGLITADAEGDFID---------ARP------GKCDAKCYKLPLFIAFIFSTLIFS 592
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
SG V VL + R +++A+GV + +FG +P P +F + + +C LRD C
Sbjct: 593 GFSG-VPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKC 651
Query: 331 GELGACVFYDTHSFRYFYLGL 351
G G C Y+ + +G+
Sbjct: 652 GHTGRCWIYNKTKMAFLLVGI 672
>AF505657-1|AAP30851.1| 719|Homo sapiens organic anion transporter
protein.
Length = 719
Score = 128 bits (310), Expect = 3e-29
Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 28/321 (8%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
+KD AA+ + N +L+ S + I G FLP YLE QF L A ++
Sbjct: 369 IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLV 428
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAA 161
GV++ L S + + I +V ++FV C + ++
Sbjct: 429 LIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINED 488
Query: 162 SDSA-------LPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
D PC+ C C ++ +S +CG+D Y SPC AGC S + N +YYNC
Sbjct: 489 YDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNC 547
Query: 215 SCI-NGSATTDL-GKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIA-IFAAIMFV 271
SCI G T D G D A P G+C C ++ +FIA IF+ ++F
Sbjct: 548 SCIKEGLITADAEGDFID---------ARP------GKCDAKCYKLPLFIAFIFSTLIFS 592
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
SG V VL + R +++A+GV + +FG +P P +F + + +C LRD C
Sbjct: 593 GFSG-VPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKC 651
Query: 331 GELGACVFYDTHSFRYFYLGL 351
G G C Y+ + +G+
Sbjct: 652 GHTGRCWIYNKTKMAFLLVGI 672
>AY342017-1|AAQ19672.1| 702|Homo sapiens organic anion transporting
polypeptide 8 protein.
Length = 702
Score = 128 bits (309), Expect = 4e-29
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
+CG GAC Y++ F YLGLS A+ F A ++
Sbjct: 604 TNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVL 639
>AK128854-1|BAC87647.1| 724|Homo sapiens 12 (SLC21A12). protein.
Length = 724
Score = 128 bits (309), Expect = 4e-29
Identities = 92/370 (24%), Positives = 156/370 (42%), Gaps = 39/370 (10%)
Query: 2 VFIAGFIVMLSCLMFFFPRQIKPEPIQLQMKKTKEKREP----------FVKDFFAAIKR 51
+F I+ SC FP+ + P ++Q KT + + +KDF AA+K
Sbjct: 323 IFAWSLIIPFSC----FPKHL-PGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKN 377
Query: 52 QITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXX 111
+ N + M S+ + +G +FLPK++E QF L + A +
Sbjct: 378 LMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQI 437
Query: 112 TSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCP-------EKSYRYLSAASDS 164
G ++ K + + + M+ C +SY +
Sbjct: 438 LGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNL 497
Query: 165 ALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTD 224
PC+ C+C + + PVCG D Y SPC AGC + +YYNCSCI T+
Sbjct: 498 IAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPV-AHRKPKVYYNCSCI--ERKTE 553
Query: 225 LGKLYDLHNRTFQELAAPEGY-AVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLI 283
+ + TF G+ A +G+C C+++ +F+ IF ++ + I
Sbjct: 554 ITSTAE----TF-------GFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSI 602
Query: 284 IRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-ACGELGACVFYDTH 342
+RC + +++A+G+ + + G +P PI+FG +D+ C L D CG GAC YD
Sbjct: 603 LRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNI 662
Query: 343 SFRYFYLGLS 352
+ + +S
Sbjct: 663 KMAHMLVAIS 672
>AJ400763-1|CAB97008.1| 702|Homo sapiens organic anion transporting
polypeptide 8 (OATP8) protein.
Length = 702
Score = 128 bits (309), Expect = 4e-29
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
+CG GAC Y++ F YLGLS A+ F A ++
Sbjct: 604 TNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVL 639
>AJ251506-1|CAB96997.1| 702|Homo sapiens organic anion transporter
8 (OATP8) protein.
Length = 702
Score = 128 bits (309), Expect = 4e-29
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
+CG GAC Y++ F YLGLS A+ F A ++
Sbjct: 604 TNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVL 639
>AF401643-1|AAQ03086.1| 724|Homo sapiens organic anion transporter
OATP-M1 protein.
Length = 724
Score = 128 bits (309), Expect = 4e-29
Identities = 92/370 (24%), Positives = 156/370 (42%), Gaps = 39/370 (10%)
Query: 2 VFIAGFIVMLSCLMFFFPRQIKPEPIQLQMKKTKEKREP----------FVKDFFAAIKR 51
+F I+ SC FP+ + P ++Q KT + + +KDF AA+K
Sbjct: 323 IFAWSLIIPFSC----FPKHL-PGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKN 377
Query: 52 QITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXX 111
+ N + M S+ + +G +FLPK++E QF L + A +
Sbjct: 378 LMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQI 437
Query: 112 TSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCP-------EKSYRYLSAASDS 164
G ++ K + + + M+ C +SY +
Sbjct: 438 LGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNL 497
Query: 165 ALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTD 224
PC+ C+C + + PVCG D Y SPC AGC + +YYNCSCI T+
Sbjct: 498 IAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPV-AHRKPKVYYNCSCI--ERKTE 553
Query: 225 LGKLYDLHNRTFQELAAPEGY-AVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLI 283
+ + TF G+ A +G+C C+++ +F+ IF ++ + I
Sbjct: 554 ITSTAE----TF-------GFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSI 602
Query: 284 IRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-ACGELGACVFYDTH 342
+RC + +++A+G+ + + G +P PI+FG +D+ C L D CG GAC YD
Sbjct: 603 LRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNI 662
Query: 343 SFRYFYLGLS 352
+ + +S
Sbjct: 663 KMAHMLVAIS 672
>AF187815-1|AAG43445.1| 702|Homo sapiens liver-specific organic
anion transporter protein.
Length = 702
Score = 128 bits (309), Expect = 4e-29
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
+CG GAC Y++ F YLGLS A+ F A ++
Sbjct: 604 TNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVL 639
>BC022461-1|AAH22461.1| 712|Homo sapiens solute carrier organic
anion transporter family, member 1C1 protein.
Length = 712
Score = 126 bits (305), Expect = 1e-28
Identities = 78/336 (23%), Positives = 144/336 (42%), Gaps = 27/336 (8%)
Query: 43 KDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXX 102
+DF ++K N + +S + + G+ ++ PKY+E+Q+ + AN V
Sbjct: 340 RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLIN 399
Query: 103 XXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAAS 162
+ G+V+ K S ++L + C L+ +
Sbjct: 400 IPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY 459
Query: 163 DSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLY 211
P C+ C C + P+CG++ TY+S C AGC S + N ++
Sbjct: 460 QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKN-IIF 518
Query: 212 YNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFV 271
YNC+C+ G A + G + R ++ P+ + +Y F+ I +
Sbjct: 519 YNCTCV-GIAASKSGNSSGIVGRCQKDNGCPQMF------------LY-FLVISVITSYT 564
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
+ G + +L++RC K+ A+G+ AI V +P P+ FG +D +C + C
Sbjct: 565 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 624
Query: 331 GELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
G G+C YD++ FR+ YLGL+ + ++ ++ + V
Sbjct: 625 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
>AY273896-1|AAP33047.2| 724|Homo sapiens OATP-H protein.
Length = 724
Score = 126 bits (305), Expect = 1e-28
Identities = 91/358 (25%), Positives = 152/358 (42%), Gaps = 39/358 (10%)
Query: 2 VFIAGFIVMLSCLMFFFPRQIKPEPIQLQMKKTKEKREP----------FVKDFFAAIKR 51
+F I+ SC FP+ + P ++Q KT + + +KDF AA+K
Sbjct: 323 IFAWSLIIPFSC----FPKHL-PGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKN 377
Query: 52 QITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXX 111
+ N + M S+ + +G +FLPK++E QF L + A +
Sbjct: 378 LMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQI 437
Query: 112 TSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCP-------EKSYRYLSAASDS 164
G ++ K + + + M+ C +SY +
Sbjct: 438 LGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNL 497
Query: 165 ALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTD 224
PC+ C+C + + PVCG D Y SPC AGC + +YYNCSCI T+
Sbjct: 498 IAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPV-AHRKPKVYYNCSCI--ERKTE 553
Query: 225 LGKLYDLHNRTFQELAAPEGY-AVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLI 283
+ + TF G+ A +G+C C+++ +F+ IF ++ + I
Sbjct: 554 ITSTAE----TF-------GFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSI 602
Query: 284 IRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-ACGELGACVFYD 340
+RC + +++A+G+ + + G +P PI+FG +D+ C L D CG GAC YD
Sbjct: 603 LRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYD 660
>AF260704-1|AAF70338.1| 712|Homo sapiens organic anion transporting
polypeptide 14 protein.
Length = 712
Score = 126 bits (305), Expect = 1e-28
Identities = 78/336 (23%), Positives = 144/336 (42%), Gaps = 27/336 (8%)
Query: 43 KDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXX 102
+DF ++K N + +S + + G+ ++ PKY+E+Q+ + AN V
Sbjct: 340 RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLIN 399
Query: 103 XXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAAS 162
+ G+V+ K S ++L + C L+ +
Sbjct: 400 IPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY 459
Query: 163 DSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLY 211
P C+ C C + P+CG++ TY+S C AGC S + N ++
Sbjct: 460 QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKN-IIF 518
Query: 212 YNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFV 271
YNC+C+ G A + G + R ++ P+ + +Y F+ I +
Sbjct: 519 YNCTCV-GIAASKSGNSSGIVGRCQKDNGCPQMF------------LY-FLVISVITSYT 564
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
+ G + +L++RC K+ A+G+ AI V +P P+ FG +D +C + C
Sbjct: 565 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 624
Query: 331 GELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
G G+C YD++ FR+ YLGL+ + ++ ++ + V
Sbjct: 625 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
>AF205076-1|AAG42208.1| 712|Homo sapiens organic anion transporter
polypeptide-related protein 5 protein.
Length = 712
Score = 126 bits (305), Expect = 1e-28
Identities = 78/336 (23%), Positives = 144/336 (42%), Gaps = 27/336 (8%)
Query: 43 KDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXX 102
+DF ++K N + +S + + G+ ++ PKY+E+Q+ + AN V
Sbjct: 340 RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLIN 399
Query: 103 XXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAAS 162
+ G+V+ K S ++L + C L+ +
Sbjct: 400 IPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY 459
Query: 163 DSALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLY 211
P C+ C C + P+CG++ TY+S C AGC S + N ++
Sbjct: 460 QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKN-IIF 518
Query: 212 YNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFV 271
YNC+C+ G A + G + R ++ P+ + +Y F+ I +
Sbjct: 519 YNCTCV-GIAASKSGNSSGIVGRCQKDNGCPQMF------------LY-FLVISVITSYT 564
Query: 272 HASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-AC 330
+ G + +L++RC K+ A+G+ AI V +P P+ FG +D +C + C
Sbjct: 565 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 624
Query: 331 GELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLV 366
G G+C YD++ FR+ YLGL+ + ++ ++ + V
Sbjct: 625 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
>U70867-1|AAC09469.1| 643|Homo sapiens prostaglandin transporter
hPGT protein.
Length = 643
Score = 122 bits (294), Expect = 2e-27
Identities = 91/382 (23%), Positives = 157/382 (41%), Gaps = 42/382 (10%)
Query: 1 MVFIAGFIVMLSCLMFFFPRQIK----------PEPIQLQMKKTKEKREPFVKDFFAAIK 50
++ + +V+ S FFFPR + E +L+ K++ F+K F
Sbjct: 261 LLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFL 320
Query: 51 RQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXX 110
R + N + + + I+G+ +FL K+LEKQ+ AN +
Sbjct: 321 RLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGM 380
Query: 111 XTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSC--PEKSYRYLSAASDSALP- 167
G+++ + V S + + I V L F+ C P + Y + S S P
Sbjct: 381 LFGGILMKRFVFSLQTIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQ 440
Query: 168 ---CSMACHCENASFSPVCGQDSYTYLSPCQAGC--MGSMQLDNNTFLYYNCSCINGSAT 222
C C C ++ F PVCG + YLSPC AGC + + +Y NCSC+ G +
Sbjct: 441 SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGSA 500
Query: 223 TDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYV-FIAIFAAIMFVHASGEVGAVL 281
+ A +G C VPC+ + I + + + + +
Sbjct: 501 S----------------------AKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYM 538
Query: 282 LIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYD 340
+++R ++ +K+ A+GV + + +P P ++G +D +C R G GAC +YD
Sbjct: 539 MVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYD 598
Query: 341 THSFRYFYLGLSAAIMFLAFIM 362
+ R YLGL L ++
Sbjct: 599 NDALRDRYLGLQMGYKALGMLL 620
>BC051347-1|AAH51347.1| 643|Homo sapiens solute carrier organic
anion transporter family, member 2A1 protein.
Length = 643
Score = 122 bits (294), Expect = 2e-27
Identities = 91/382 (23%), Positives = 157/382 (41%), Gaps = 42/382 (10%)
Query: 1 MVFIAGFIVMLSCLMFFFPRQIK----------PEPIQLQMKKTKEKREPFVKDFFAAIK 50
++ + +V+ S FFFPR + E +L+ K++ F+K F
Sbjct: 261 LLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFL 320
Query: 51 RQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXX 110
R + N + + + I+G+ +FL K+LEKQ+ AN +
Sbjct: 321 RLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGM 380
Query: 111 XTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSC--PEKSYRYLSAASDSALP- 167
G+++ + V S + + I V L F+ C P + Y + S S P
Sbjct: 381 LFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQ 440
Query: 168 ---CSMACHCENASFSPVCGQDSYTYLSPCQAGC--MGSMQLDNNTFLYYNCSCINGSAT 222
C C C ++ F PVCG + YLSPC AGC + + +Y NCSC+ G +
Sbjct: 441 SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGSA 500
Query: 223 TDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYV-FIAIFAAIMFVHASGEVGAVL 281
+ A +G C VPC+ + I + + + + +
Sbjct: 501 S----------------------AKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYM 538
Query: 282 LIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYD 340
+++R ++ +K+ A+GV + + +P P ++G +D +C R G GAC +YD
Sbjct: 539 MVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYD 598
Query: 341 THSFRYFYLGLSAAIMFLAFIM 362
+ R YLGL L ++
Sbjct: 599 NDALRDRYLGLQMGYKALGMLL 620
>BC041140-1|AAH41140.2| 643|Homo sapiens solute carrier organic
anion transporter family, member 2A1 protein.
Length = 643
Score = 122 bits (294), Expect = 2e-27
Identities = 91/382 (23%), Positives = 157/382 (41%), Gaps = 42/382 (10%)
Query: 1 MVFIAGFIVMLSCLMFFFPRQIK----------PEPIQLQMKKTKEKREPFVKDFFAAIK 50
++ + +V+ S FFFPR + E +L+ K++ F+K F
Sbjct: 261 LLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFL 320
Query: 51 RQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXX 110
R + N + + + I+G+ +FL K+LEKQ+ AN +
Sbjct: 321 RLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGM 380
Query: 111 XTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSC--PEKSYRYLSAASDSALP- 167
G+++ + V S + + I V L F+ C P + Y + S S P
Sbjct: 381 LFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQ 440
Query: 168 ---CSMACHCENASFSPVCGQDSYTYLSPCQAGC--MGSMQLDNNTFLYYNCSCINGSAT 222
C C C ++ F PVCG + YLSPC AGC + + +Y NCSC+ G +
Sbjct: 441 SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGSA 500
Query: 223 TDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYV-FIAIFAAIMFVHASGEVGAVL 281
+ A +G C VPC+ + I + + + + +
Sbjct: 501 S----------------------AKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYM 538
Query: 282 LIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYD 340
+++R ++ +K+ A+GV + + +P P ++G +D +C R G GAC +YD
Sbjct: 539 MVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYD 598
Query: 341 THSFRYFYLGLSAAIMFLAFIM 362
+ R YLGL L ++
Sbjct: 599 NDALRDRYLGLQMGYKALGMLL 620
>AF056732-1|AAC62004.1| 643|Homo sapiens prostaglandin transporter
protein.
Length = 643
Score = 122 bits (294), Expect = 2e-27
Identities = 91/382 (23%), Positives = 157/382 (41%), Gaps = 42/382 (10%)
Query: 1 MVFIAGFIVMLSCLMFFFPRQIK----------PEPIQLQMKKTKEKREPFVKDFFAAIK 50
++ + +V+ S FFFPR + E +L+ K++ F+K F
Sbjct: 261 LLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRFPCIFL 320
Query: 51 RQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXX 110
R + N + + + I+G+ +FL K+LEKQ+ AN +
Sbjct: 321 RLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGM 380
Query: 111 XTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSC--PEKSYRYLSAASDSALP- 167
G+++ + V S + + I V L F+ C P + Y + S S P
Sbjct: 381 LFGGILMKRFVFSLQTIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIHPQ 440
Query: 168 ---CSMACHCENASFSPVCGQDSYTYLSPCQAGC--MGSMQLDNNTFLYYNCSCINGSAT 222
C C C ++ F PVCG + YLSPC AGC + + +Y NCSC+ G +
Sbjct: 441 SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCVTGGSA 500
Query: 223 TDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYV-FIAIFAAIMFVHASGEVGAVL 281
+ A +G C VPC+ + I + + + + +
Sbjct: 501 S----------------------AKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYM 538
Query: 282 LIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYD 340
+++R ++ +K+ A+GV + + +P P ++G +D +C R G GAC +YD
Sbjct: 539 MVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYD 598
Query: 341 THSFRYFYLGLSAAIMFLAFIM 362
+ R YLGL L ++
Sbjct: 599 NDALRDRYLGLQMGYKALGMLL 620
>AY442325-1|AAS01767.1| 687|Homo sapiens organic anion transporter
LST-3b protein.
Length = 687
Score = 118 bits (283), Expect = 5e-26
Identities = 93/391 (23%), Positives = 162/391 (41%), Gaps = 47/391 (12%)
Query: 4 IAGFIVMLSCLMFFF-------PRQIKPEPIQLQMKKTKEKREPF-------------VK 43
++G + ++S + FFF P++ + + L + KT +KR V
Sbjct: 264 VSGIVSIISSIPFFFLPLNPNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVT 323
Query: 44 DFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXX 103
FF ++K +TN + + ++LH+ +++ K +E+Q+ N +
Sbjct: 324 GFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLAL 383
Query: 104 XXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAASD 163
+ G +I K S + ++ V F+ C KS L+ D
Sbjct: 384 PTVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYD 443
Query: 164 SALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYY 212
P C+ C+C+ + + PVCG + TYLSPC AGC S + ++Y
Sbjct: 444 GNSPVRSHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSG-NKEPIVFY 502
Query: 213 NCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVH 272
NCSC+ ++ L N+ + +A G + S +Y I + A F+
Sbjct: 503 NCSCV---------EVIGLQNKNY---SAHLGECPRDDACTRKSYVYFVIQVLDA--FLC 548
Query: 273 ASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACG 331
A G +L+IR KA+A+G + G + PI FGA +D C + +CG
Sbjct: 549 AVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCG 608
Query: 332 ELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
GAC Y++ + GL A++F ++
Sbjct: 609 ARGACRIYNSTYLGRAFFGLKVALIFPVLVL 639
>AY257470-1|AAP81211.1| 687|Homo sapiens liver-specific organic
anion transporter 3TM12 protein.
Length = 687
Score = 118 bits (283), Expect = 5e-26
Identities = 93/391 (23%), Positives = 162/391 (41%), Gaps = 47/391 (12%)
Query: 4 IAGFIVMLSCLMFFF-------PRQIKPEPIQLQMKKTKEKREPF-------------VK 43
++G + ++S + FFF P++ + + L + KT +KR V
Sbjct: 264 VSGIVSIISSIPFFFLPLNPNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVT 323
Query: 44 DFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXX 103
FF ++K +TN + + ++LH+ +++ K +E+Q+ N +
Sbjct: 324 GFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLAL 383
Query: 104 XXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAASD 163
+ G +I K S + ++ V F+ C KS L+ D
Sbjct: 384 PTVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYD 443
Query: 164 SALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYY 212
P C+ C+C+ + + PVCG + TYLSPC AGC S + ++Y
Sbjct: 444 GNSPVRSHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSG-NKEPIVFY 502
Query: 213 NCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVH 272
NCSC+ ++ L N+ + +A G + S +Y I + A F+
Sbjct: 503 NCSCV---------EVIGLQNKNY---SAHLGECPRDDACTRKSYVYFVIQVLDA--FLC 548
Query: 273 ASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACG 331
A G +L+IR KA+A+G + G + PI FGA +D C + +CG
Sbjct: 549 AVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCG 608
Query: 332 ELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
GAC Y++ + GL A++F ++
Sbjct: 609 ARGACRIYNSTYLGRAFFGLKVALIFPVLVL 639
>AF401642-1|AAQ03085.1| 640|Homo sapiens liver-specific organic
anion transporter LST-3 protein.
Length = 640
Score = 118 bits (283), Expect = 5e-26
Identities = 93/391 (23%), Positives = 162/391 (41%), Gaps = 47/391 (12%)
Query: 4 IAGFIVMLSCLMFFF-------PRQIKPEPIQLQMKKTKEKREPF-------------VK 43
++G + ++S + FFF P++ + + L + KT +KR V
Sbjct: 217 VSGIVSIISSIPFFFLPLNPNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVT 276
Query: 44 DFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXXXX 103
FF ++K +TN + + ++LH+ +++ K +E+Q+ N +
Sbjct: 277 GFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLAL 336
Query: 104 XXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSAASD 163
+ G +I K S + ++ V F+ C KS L+ D
Sbjct: 337 PTVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYD 396
Query: 164 SALP-----------CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYY 212
P C+ C+C+ + + PVCG + TYLSPC AGC S + ++Y
Sbjct: 397 GNSPVRSHVGVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSG-NKEPIVFY 455
Query: 213 NCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVH 272
NCSC+ ++ L N+ + +A G + S +Y I + A F+
Sbjct: 456 NCSCV---------EVIGLQNKNY---SAHLGECPRDDACTRKSYVYFVIQVLDA--FLC 501
Query: 273 ASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACG 331
A G +L+IR KA+A+G + G + PI FGA +D C + +CG
Sbjct: 502 AVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCG 561
Query: 332 ELGACVFYDTHSFRYFYLGLSAAIMFLAFIM 362
GAC Y++ + GL A++F ++
Sbjct: 562 ARGACRIYNSTYLGRAFFGLKVALIFPVLVL 592
>AY442326-1|AAS01768.1| 748|Homo sapiens organic anion transporter
LST-3c protein.
Length = 748
Score = 116 bits (278), Expect = 2e-25
Identities = 92/337 (27%), Positives = 145/337 (43%), Gaps = 34/337 (10%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSA-AIMFLAFIM 362
+CG GAC Y++ F L A AI F + IM
Sbjct: 604 TNSCGAQGACRIYNSVFFGIVQPELKALAIGFHSMIM 640
Score = 45.6 bits (103), Expect = 3e-04
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 292 KAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYDTHSFRYFYLG 350
KA+A+G + G + PI FGA +D C + +CG GAC Y++ + G
Sbjct: 629 KALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFG 688
Query: 351 LSAAIMFLAFIM 362
L A++F ++
Sbjct: 689 LKVALIFPVLVL 700
>AY257471-1|AAP81212.1| 748|Homo sapiens liver-specific organic
anion transporter 3TM13 protein.
Length = 748
Score = 116 bits (278), Expect = 2e-25
Identities = 92/337 (27%), Positives = 145/337 (43%), Gaps = 34/337 (10%)
Query: 42 VKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAXX 101
V FF ++K +TN + + ++L + G ++++ KY+E+Q+ AN +
Sbjct: 322 VTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGII 381
Query: 102 XXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYL--- 158
G +I K S + I + + C KS L
Sbjct: 382 TIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLT 441
Query: 159 -----SAASDSALP---CSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFL 210
S AS +P C+ C+C+ + + PVCG + TYLSPC AGC S + +T +
Sbjct: 442 YDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHT-V 500
Query: 211 YYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGEC--GVPCS-QIYVFIAIFAA 267
+YNCSC+ ++ L NR + A GEC C+ + ++++AI
Sbjct: 501 FYNCSCV---------EVTGLQNRNYS--------AHLGECPRDNTCTRKFFIYVAIQVI 543
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLR 326
A+G +LL ++ KA+AMG I G + PI FGA +D C +
Sbjct: 544 NSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWS 603
Query: 327 DYACGELGACVFYDTHSFRYFYLGLSA-AIMFLAFIM 362
+CG GAC Y++ F L A AI F + IM
Sbjct: 604 TNSCGAQGACRIYNSVFFGIVQPELKALAIGFHSMIM 640
Score = 45.6 bits (103), Expect = 3e-04
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 292 KAMAMGVIQFAIGVFGNVPCPIVFGAAVDAAC-RLRDYACGELGACVFYDTHSFRYFYLG 350
KA+A+G + G + PI FGA +D C + +CG GAC Y++ + G
Sbjct: 629 KALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFG 688
Query: 351 LSAAIMFLAFIM 362
L A++F ++
Sbjct: 689 LKVALIFPVLVL 700
>BC015727-1|AAH15727.1| 722|Homo sapiens solute carrier organic
anion transporter family, member 4A1 protein.
Length = 722
Score = 109 bits (261), Expect = 2e-23
Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 32/302 (10%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELA 240
VCG D Y S C AGC + + + + +Y +CSCI Q L+
Sbjct: 518 VCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------------------QNLS 559
Query: 241 APEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQ 300
+ G+A +G+C C + + + ++F + A+ +RC ++ A+G+
Sbjct: 560 SGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQW 619
Query: 301 FAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF-RY-FYLGLSAAIMFL 358
+ + G +P PI FG +D AC L CG+ G+C+ Y + RY +GL ++ +
Sbjct: 620 IVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGV 679
Query: 359 AF 360
F
Sbjct: 680 LF 681
>AL357033-2|CAC14920.1| 722|Homo sapiens solute carrier organic
anion transporter family, member 4A1 protein.
Length = 722
Score = 109 bits (261), Expect = 2e-23
Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 32/302 (10%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELA 240
VCG D Y S C AGC + + + + +Y +CSCI Q L+
Sbjct: 518 VCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------------------QNLS 559
Query: 241 APEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQ 300
+ G+A +G+C C + + + ++F + A+ +RC ++ A+G+
Sbjct: 560 SGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQW 619
Query: 301 FAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF-RY-FYLGLSAAIMFL 358
+ + G +P PI FG +D AC L CG+ G+C+ Y + RY +GL ++ +
Sbjct: 620 IVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGV 679
Query: 359 AF 360
F
Sbjct: 680 LF 681
>AF205072-1|AAG42204.1| 722|Homo sapiens organic anion transporter
polypeptide-related protein 1 protein.
Length = 722
Score = 109 bits (261), Expect = 2e-23
Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 32/302 (10%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELA 240
VCG D Y S C AGC + + + + +Y +CSCI Q L+
Sbjct: 518 VCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------------------QNLS 559
Query: 241 APEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQ 300
+ G+A +G+C C + + + ++F + A+ +RC ++ A+G+
Sbjct: 560 SGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQW 619
Query: 301 FAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF-RY-FYLGLSAAIMFL 358
+ + G +P PI FG +D AC L CG+ G+C+ Y + RY +GL ++ +
Sbjct: 620 IVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGV 679
Query: 359 AF 360
F
Sbjct: 680 LF 681
>AF187817-1|AAG43447.1| 722|Homo sapiens colon organic anion
transporter protein.
Length = 722
Score = 109 bits (261), Expect = 2e-23
Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 32/302 (10%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELA 240
VCG D Y S C AGC + + + + +Y +CSCI Q L+
Sbjct: 518 VCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------------------QNLS 559
Query: 241 APEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQ 300
+ G+A +G+C C + + + ++F + A+ +RC ++ A+G+
Sbjct: 560 SGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQW 619
Query: 301 FAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF-RY-FYLGLSAAIMFL 358
+ + G +P PI FG +D AC L CG+ G+C+ Y + RY +GL ++ +
Sbjct: 620 IVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGV 679
Query: 359 AF 360
F
Sbjct: 680 LF 681
>AB031051-1|BAA89288.1| 722|Homo sapiens organic anion transporter
OATP-E protein.
Length = 722
Score = 109 bits (261), Expect = 2e-23
Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 32/302 (10%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELA 240
VCG D Y S C AGC + + + + +Y +CSCI Q L+
Sbjct: 518 VCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------------------QNLS 559
Query: 241 APEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQ 300
+ G+A +G+C C + + + ++F + A+ +RC ++ A+G+
Sbjct: 560 SGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQW 619
Query: 301 FAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF-RY-FYLGLSAAIMFL 358
+ + G +P PI FG +D AC L CG+ G+C+ Y + RY +GL ++ +
Sbjct: 620 IVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGV 679
Query: 359 AF 360
F
Sbjct: 680 LF 681
>AK131445-1|BAD18590.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ16580 fis, clone TESTI2050780. ).
Length = 466
Score = 103 bits (246), Expect = 2e-21
Identities = 64/189 (33%), Positives = 95/189 (50%), Gaps = 21/189 (11%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCI-NGSATTDL 225
PC+ C C ++ +S +CG+D Y SPC AGC S + N +YYNCSCI G T D
Sbjct: 248 PCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSCIKEGLITADA 306
Query: 226 -GKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIA-IFAAIMFVHASGEVGAVLLI 283
G D A P G+C C ++ +FIA IF+ ++F SG V VL +
Sbjct: 307 EGDFID---------ARP------GKCDAKCYKLPLFIAFIFSTLIFSGFSG-VPIVLAM 350
Query: 284 IRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDY-ACGELGACVFYDTH 342
R +++A+GV + +FG +P P +F + + +C LRD CG G C Y+
Sbjct: 351 TRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHRGRCWIYNKT 410
Query: 343 SFRYFYLGL 351
+ +G+
Sbjct: 411 KMAFLLVGI 419
>AK023410-1|BAB14566.1| 583|Homo sapiens protein ( Homo sapiens
cDNA FLJ13348 fis, clone OVARC1002127, weakly similar to
SODIUM-INDEPENDENT ORGANIC ANION TRANSPORTER 2. ).
Length = 583
Score = 101 bits (242), Expect = 5e-21
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 19/205 (9%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLD-NNTFLYYNCSCINGSATTDL 225
PC+ AC C+ +SPVCG D Y S C AGC + + + + +Y +CSCI
Sbjct: 356 PCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIP------- 408
Query: 226 GKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIR 285
Q L++ G+A +G+C C + + + ++F + A+ +R
Sbjct: 409 -----------QNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLR 457
Query: 286 CTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSFR 345
C ++ A+G+ + + G +P PI FG +D AC L CG+ G+C+ Y +
Sbjct: 458 CVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMS 517
Query: 346 YFYLGLSAAIMFLAFIMDLLVWSKA 370
+ L + L + + S+A
Sbjct: 518 RYILIMGLLYKVLGVLFFAIASSRA 542
>BC041095-1|AAH41095.1| 709|Homo sapiens solute carrier organic
anion transporter family, member 2B1 protein.
Length = 709
Score = 94.7 bits (225), Expect = 5e-19
Identities = 79/324 (24%), Positives = 132/324 (40%), Gaps = 38/324 (11%)
Query: 41 FVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAX 100
F+K F + + + + I + S V +G+ +FLPK+LE+QF + ANL+
Sbjct: 356 FIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGC 415
Query: 101 XXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSA 160
GV++ +L + + L F+ C ++
Sbjct: 416 LSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITH 475
Query: 161 ASDSALP-------CSMACHCENASFSPVCGQDS-YTYLSPCQAGCMGSM---QLDNNTF 209
+ SA P C AC C F+PVC + Y++PC AGC + LDN+
Sbjct: 476 QT-SAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQV 534
Query: 210 LYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAV-SGECGVPCSQIYV-FIAIFAA 267
Y NCSC+ EG V +G C CS + V F+ + +
Sbjct: 535 FYTNCSCV------------------------VEGNPVLAGSCDSTCSHLVVPFLLLVSL 570
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRD 327
+ + +LI+R K DK +A+G+ + + +P P++ G+A+D C
Sbjct: 571 GSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWA 630
Query: 328 YACGELGACVFYDTHSFRYFYLGL 351
+CG C +Y+ R ++GL
Sbjct: 631 LSCGRRAVCRYYNNDLLRNRFIGL 654
>AF205073-1|AAG42205.1| 687|Homo sapiens organic anion transporter
polypeptide-related protein 2 protein.
Length = 687
Score = 94.7 bits (225), Expect = 5e-19
Identities = 79/324 (24%), Positives = 132/324 (40%), Gaps = 38/324 (11%)
Query: 41 FVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAX 100
F+K F + + + + I + S V +G+ +FLPK+LE+QF + ANL+
Sbjct: 334 FIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGC 393
Query: 101 XXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSA 160
GV++ +L + + L F+ C ++
Sbjct: 394 LSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITH 453
Query: 161 ASDSALP-------CSMACHCENASFSPVCGQDS-YTYLSPCQAGCMGSM---QLDNNTF 209
+ SA P C AC C F+PVC + Y++PC AGC + LDN+
Sbjct: 454 QT-SAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQV 512
Query: 210 LYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAV-SGECGVPCSQIYV-FIAIFAA 267
Y NCSC+ EG V +G C CS + V F+ + +
Sbjct: 513 FYTNCSCV------------------------VEGNPVLAGSCDSTCSHLVVPFLLLVSL 548
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRD 327
+ + +LI+R K DK +A+G+ + + +P P++ G+A+D C
Sbjct: 549 GSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWA 608
Query: 328 YACGELGACVFYDTHSFRYFYLGL 351
+CG C +Y+ R ++GL
Sbjct: 609 LSCGRRAVCRYYNNDLLRNRFIGL 632
>AB026256-1|BAA78638.1| 709|Homo sapiens organic anion transporter
OATP-B protein.
Length = 709
Score = 94.7 bits (225), Expect = 5e-19
Identities = 79/324 (24%), Positives = 132/324 (40%), Gaps = 38/324 (11%)
Query: 41 FVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAX 100
F+K F + + + + I + S V +G+ +FLPK+LE+QF + ANL+
Sbjct: 356 FIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGC 415
Query: 101 XXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSA 160
GV++ +L + + L F+ C ++
Sbjct: 416 LSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITH 475
Query: 161 ASDSALP-------CSMACHCENASFSPVCGQDS-YTYLSPCQAGCMGSM---QLDNNTF 209
+ SA P C AC C F+PVC + Y++PC AGC + LDN+
Sbjct: 476 QT-SAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQV 534
Query: 210 LYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAV-SGECGVPCSQIYV-FIAIFAA 267
Y NCSC+ EG V +G C CS + V F+ + +
Sbjct: 535 FYTNCSCV------------------------VEGNPVLAGSCDSTCSHLVVPFLLLVSL 570
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRD 327
+ + +LI+R K DK +A+G+ + + +P P++ G+A+D C
Sbjct: 571 GSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWA 630
Query: 328 YACGELGACVFYDTHSFRYFYLGL 351
+CG C +Y+ R ++GL
Sbjct: 631 LSCGRRAVCRYYNNDLLRNRFIGL 654
>AB020687-1|BAA74903.2| 727|Homo sapiens KIAA0880 protein protein.
Length = 727
Score = 94.7 bits (225), Expect = 5e-19
Identities = 79/324 (24%), Positives = 132/324 (40%), Gaps = 38/324 (11%)
Query: 41 FVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSAX 100
F+K F + + + + I + S V +G+ +FLPK+LE+QF + ANL+
Sbjct: 374 FIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGC 433
Query: 101 XXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAGMVALMFVSCPEKSYRYLSA 160
GV++ +L + + L F+ C ++
Sbjct: 434 LSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITH 493
Query: 161 ASDSALP-------CSMACHCENASFSPVCGQDS-YTYLSPCQAGCMGSM---QLDNNTF 209
+ SA P C AC C F+PVC + Y++PC AGC + LDN+
Sbjct: 494 QT-SAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQV 552
Query: 210 LYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAV-SGECGVPCSQIYV-FIAIFAA 267
Y NCSC+ EG V +G C CS + V F+ + +
Sbjct: 553 FYTNCSCV------------------------VEGNPVLAGSCDSTCSHLVVPFLLLVSL 588
Query: 268 IMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRD 327
+ + +LI+R K DK +A+G+ + + +P P++ G+A+D C
Sbjct: 589 GSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWA 648
Query: 328 YACGELGACVFYDTHSFRYFYLGL 351
+CG C +Y+ R ++GL
Sbjct: 649 LSCGRRAVCRYYNNDLLRNRFIGL 672
>AF085224-1|AAD52694.1| 579|Homo sapiens brain organic anion
transporter subtype OATP1b protein.
Length = 579
Score = 85.8 bits (203), Expect = 2e-16
Identities = 71/300 (23%), Positives = 122/300 (40%), Gaps = 36/300 (12%)
Query: 22 IKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPK 81
IK E Q ++ K+++ KDF +K N I M SV+ + SF+PK
Sbjct: 280 IKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPK 339
Query: 82 YLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXXXXXXXIYSAG 141
YLE+Q+ + + DA + G+++ K + +Q +
Sbjct: 340 YLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLL 399
Query: 142 MVALMFVSCPEKSY-----------RYLSAASDSALPCSMACHCENASFSPVCGQDSYTY 190
++C S + L +D C++ C+C + + PVCG + +Y
Sbjct: 400 YFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSY 459
Query: 191 LSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGE 250
LS C AGC S+ N ++ NCSCI S + AV G
Sbjct: 460 LSACLAGCETSIGTGIN-MVFQNCSCIQTSGNSS---------------------AVLGL 497
Query: 251 C--GVPCS-QIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFG 307
C G CS + F+ + A F+++ + ++++RC +K++ +G+ F VFG
Sbjct: 498 CDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFG 557
>AF104334-1|AAF15545.1| 661|Homo sapiens putative organic anion
transporter protein.
Length = 661
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 11/137 (8%)
Query: 72 ISGVYSFLPKYLEKQFRLPTHDANLVSAXXXXXXXXXXXXTSGVVILKLVPSARQVXXXX 131
I+G+ +F PK+LE QF L +A + G + KL V
Sbjct: 399 ITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFC 458
Query: 132 XXXXXIYSAGMVALMFVSCPEKSYRYLSAASDSAL----------PCSMACHCENASFSP 181
+ G++ + CP ++A+ +L PC+ AC C+ +SP
Sbjct: 459 LFCTVVSLLGILVFS-LHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSP 517
Query: 182 VCGQDSYTYLSPCQAGC 198
VCG D Y S C AGC
Sbjct: 518 VCGSDGLMYFSLCHAGC 534
>AL357033-3|CAC14921.1| 151|Homo sapiens solute carrier organic
anion transporter family, member 4A1 protein.
Length = 151
Score = 51.2 bits (117), Expect = 6e-06
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 285 RCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF 344
RC ++ A+G+ + + G +P PI FG +D AC L CG+ G+C+ Y +
Sbjct: 33 RCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAM 92
Query: 345 -RY-FYLGLSAAIMFLAF 360
RY +GL ++ + F
Sbjct: 93 SRYILIMGLLYKVLGVLF 110
>AK000551-1|BAA91247.1| 124|Homo sapiens protein ( Homo sapiens
cDNA FLJ20544 fis, clone KAT11437. ).
Length = 124
Score = 51.2 bits (117), Expect = 6e-06
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 285 RCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSF 344
RC ++ A+G+ + + G +P PI FG +D AC L CG+ G+C+ Y +
Sbjct: 6 RCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAM 65
Query: 345 -RY-FYLGLSAAIMFLAF 360
RY +GL ++ + F
Sbjct: 66 SRYILIMGLLYKVLGVLF 83
>BC042452-1|AAH42452.2| 408|Homo sapiens SLCO1A2 protein protein.
Length = 408
Score = 43.2 bits (97), Expect = 0.002
Identities = 24/73 (32%), Positives = 37/73 (50%)
Query: 22 IKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPK 81
IK E Q ++ K+++ KDF +K N I M SV+ + SF+PK
Sbjct: 262 IKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPK 321
Query: 82 YLEKQFRLPTHDA 94
YLE+Q+ + + DA
Sbjct: 322 YLEQQYGISSSDA 334
>D50406-1|BAA34060.1| 971|Homo sapiens ST15 protein.
Length = 971
Score = 37.9 bits (84), Expect = 0.065
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
Query: 159 SAASDSALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
S+ D + C+C + F PVCGQ+ TY S C A C+G L ++ F + +C
Sbjct: 620 SSEDDRRTFTGLPCNCAD-QFVPVCGQNGRTYPSACIARCVG---LQDHQFEFGSC 671
>AL158830-3|CAD13384.2| 971|Homo sapiens
reversion-inducing-cysteine-rich protein with kazal
motifs protein.
Length = 971
Score = 37.9 bits (84), Expect = 0.065
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
Query: 159 SAASDSALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
S+ D + C+C + F PVCGQ+ TY S C A C+G L ++ F + +C
Sbjct: 620 SSEDDRRTFTGLPCNCAD-QFVPVCGQNGRTYPSACIARCVG---LQDHQFEFGSC 671
>AL138834-5|CAH70155.1| 971|Homo sapiens
reversion-inducing-cysteine-rich protein with kazal
motifs protein.
Length = 971
Score = 37.9 bits (84), Expect = 0.065
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
Query: 159 SAASDSALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNC 214
S+ D + C+C + F PVCGQ+ TY S C A C+G L ++ F + +C
Sbjct: 620 SSEDDRRTFTGLPCNCAD-QFVPVCGQNGRTYPSACIARCVG---LQDHQFEFGSC 671
>BC131613-1|AAI31614.1| 292|Homo sapiens keratin associated protein
10-9 protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.26
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 150 CPEKSYRYLSAASDSALP-CSMACHCENASFSPVCGQDSYT--YLSPCQAGCMGS 201
C + SY+ AS S P C + C+ +P C +DSY+ S CQ C S
Sbjct: 121 CQQSSYQPACCASSSCQPACCVPVCCKPVCCAPTCSEDSYSCCQQSSCQPACCTS 175
>AB076356-1|BAD01543.1| 292|Homo sapiens keratin associated protein
protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.26
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 150 CPEKSYRYLSAASDSALP-CSMACHCENASFSPVCGQDSYT--YLSPCQAGCMGS 201
C + SY+ AS S P C + C+ +P C +DSY+ S CQ C S
Sbjct: 121 CQQSSYQPACCASSSCQPACCVPVCCKPVCCAPTCSEDSYSCCQQSSCQPACCTS 175
>X83961-1|CAA58791.1| 380|Homo sapiens transmembrane protein
protein.
Length = 380
Score = 35.5 bits (78), Expect = 0.34
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 156 RYLSAASDSALPCSMACH--CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLDNNTFL 210
+Y + + A C+ C SF+PVC D +Y +PC +A C+ Q+D +
Sbjct: 174 KYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID----I 229
Query: 211 YYNCSCINGSATTDLGKLYD 230
+ C + T+ LGK D
Sbjct: 230 RHLGHCTDTDDTSLLGKKDD 249
>U19878-1|AAA64622.1| 380|Homo sapiens transmembrane protein
protein.
Length = 380
Score = 35.5 bits (78), Expect = 0.34
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 156 RYLSAASDSALPCSMACH--CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLDNNTFL 210
+Y + + A C+ C SF+PVC D +Y +PC +A C+ Q+D +
Sbjct: 174 KYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID----I 229
Query: 211 YYNCSCINGSATTDLGKLYD 230
+ C + T+ LGK D
Sbjct: 230 RHLGHCTDTDDTSLLGKKDD 249
>BC035056-1|AAH35056.1| 380|Homo sapiens transmembrane protein with
EGF-like and two follistatin-like domains 1 protein.
Length = 380
Score = 35.5 bits (78), Expect = 0.34
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 156 RYLSAASDSALPCSMACH--CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLDNNTFL 210
+Y + + A C+ C SF+PVC D +Y +PC +A C+ Q+D +
Sbjct: 174 KYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID----I 229
Query: 211 YYNCSCINGSATTDLGKLYD 230
+ C + T+ LGK D
Sbjct: 230 RHLGHCTDTDDTSLLGKKDD 249
>AL354917-2|CAI16192.1| 380|Homo sapiens transmembrane protein with
EGF-like and two follistatin-like domains 1 protein.
Length = 380
Score = 35.5 bits (78), Expect = 0.34
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 156 RYLSAASDSALPCSMACH--CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLDNNTFL 210
+Y + + A C+ C SF+PVC D +Y +PC +A C+ Q+D +
Sbjct: 174 KYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID----I 229
Query: 211 YYNCSCINGSATTDLGKLYD 230
+ C + T+ LGK D
Sbjct: 230 RHLGHCTDTDDTSLLGKKDD 249
>AL353805-7|CAI12543.1| 380|Homo sapiens transmembrane protein with
EGF-like and two follistatin-like domains 1 protein.
Length = 380
Score = 35.5 bits (78), Expect = 0.34
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 156 RYLSAASDSALPCSMACH--CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLDNNTFL 210
+Y + + A C+ C SF+PVC D +Y +PC +A C+ Q+D +
Sbjct: 174 KYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID----I 229
Query: 211 YYNCSCINGSATTDLGKLYD 230
+ C + T+ LGK D
Sbjct: 230 RHLGHCTDTDDTSLLGKKDD 249
>BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein.
Length = 719
Score = 33.1 bits (72), Expect = 1.8
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQ 195
PC C++ SPVCG D TY + C+
Sbjct: 184 PCVCDFSCQSVPGSPVCGSDGVTYSTECE 212
Score = 31.5 bits (68), Expect = 5.6
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLD 205
CE+ PVCG D TY S C +A C+ Q++
Sbjct: 105 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIE 139
>AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 33.1 bits (72), Expect = 1.8
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQ 195
PC C++ SPVCG D TY + C+
Sbjct: 702 PCVCDFSCQSVPGSPVCGSDGVTYSTECE 730
Score = 31.5 bits (68), Expect = 5.6
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLD 205
CE+ PVCG D TY S C +A C+ Q++
Sbjct: 623 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIE 657
>AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.
Length = 2026
Score = 33.1 bits (72), Expect = 1.8
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQ 195
PC C++ SPVCG D TY + C+
Sbjct: 683 PCVCDFSCQSVPGSPVCGSDGVTYSTECE 711
Score = 31.5 bits (68), Expect = 5.6
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLD 205
CE+ PVCG D TY S C +A C+ Q++
Sbjct: 604 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIE 638
>AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 33.1 bits (72), Expect = 1.8
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 167 PCSMACHCENASFSPVCGQDSYTYLSPCQ 195
PC C++ SPVCG D TY + C+
Sbjct: 702 PCVCDFSCQSVPGSPVCGSDGVTYSTECE 730
Score = 31.5 bits (68), Expect = 5.6
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLD 205
CE+ PVCG D TY S C +A C+ Q++
Sbjct: 623 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIE 657
>S44195-1|AAB23327.1| 62|Homo sapiens agrin protein.
Length = 62
Score = 32.7 bits (71), Expect = 2.4
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 3/35 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQLD 205
CE+ PVCG D TY S C +A C+ Q++
Sbjct: 24 CEHPPHGPVCGSDGVTYGSACELREAACLQQTQIE 58
>D87465-1|BAA13404.2| 510|Homo sapiens KIAA0275 protein.
Length = 510
Score = 32.7 bits (71), Expect = 2.4
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQL 204
C A + VCG D +TY S C Q C+ S QL
Sbjct: 225 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL 258
>BC023558-1|AAH23558.1| 424|Homo sapiens SPOCK2 protein protein.
Length = 424
Score = 32.7 bits (71), Expect = 2.4
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQL 204
C A + VCG D +TY S C Q C+ S QL
Sbjct: 139 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL 172
>AY358921-1|AAQ89280.1| 424|Homo sapiens SPOCK2 protein.
Length = 424
Score = 32.7 bits (71), Expect = 2.4
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQL 204
C A + VCG D +TY S C Q C+ S QL
Sbjct: 139 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL 172
>AJ001453-1|CAA04774.1| 424|Homo sapiens testican-2 protein.
Length = 424
Score = 32.7 bits (71), Expect = 2.4
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Query: 174 CENASFSPVCGQDSYTYLSPC---QAGCMGSMQL 204
C A + VCG D +TY S C Q C+ S QL
Sbjct: 139 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL 172
>BC022367-1|AAH22367.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AL590733-2|CAH71125.1| 292|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 292
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AL590733-1|CAH71124.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AL031776-2|CAI20142.1| 292|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 292
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AL031776-1|CAI20141.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AK027346-1|BAB55051.1| 292|Homo sapiens protein ( Homo sapiens
cDNA FLJ14440 fis, clone HEMBB1000915, weakly similar to
SUBTILISIN-LIKE PROTEASE PACE4 PRECURSOR (EC 3.4.21.-).
).
Length = 292
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>AF251057-1|AAK34947.1| 272|Homo sapiens thrombospondin protein.
Length = 272
Score = 31.5 bits (68), Expect = 5.6
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 1/67 (1%)
Query: 143 VALMFVSCPEKSYRYLSAASDSALPCSMACH-CENASFSPVCGQDSYTYLSPCQAGCMGS 201
+ + SCP Y + C C C N +F C Y +L C C
Sbjct: 73 IGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEG 132
Query: 202 MQLDNNT 208
++ +N+T
Sbjct: 133 LEANNHT 139
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 194 CQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEG-YAVSGECG 252
C AGC G D L++N S G L + TF+ + PEG Y C
Sbjct: 240 CAAGCTGPKHSDCLACLHFNHS---GICELHCPALVTYNTDTFESMPNPEGRYTFGASCV 296
Query: 253 VPCSQIYV 260
C Y+
Sbjct: 297 TACPYNYL 304
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 194 CQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEG-YAVSGECG 252
C AGC G D L++N S G L + TF+ + PEG Y C
Sbjct: 240 CAAGCTGPKHSDCLACLHFNHS---GICELHCPALVTYNTDTFESMPNPEGRYTFGASCV 296
Query: 253 VPCSQIYV 260
C Y+
Sbjct: 297 TACPYNYL 304
>CR541813-1|CAG46612.1| 317|Homo sapiens FST protein.
Length = 317
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Query: 148 VSCPEKSYRYLSAASDS-ALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDN 206
V CP S + +++ + C+ C +S +CG D TY S C + L
Sbjct: 171 VFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLR-KATCLLGR 229
Query: 207 NTFLYYNCSCINGSATTDL 225
+ L Y CI + D+
Sbjct: 230 SIGLVYEGKCIKAKSCEDI 248
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 194 CQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEG-YAVSGECG 252
C AGC G D L++N S G L + TF+ + PEG Y C
Sbjct: 240 CAAGCTGPKHSDCLACLHFNHS---GICELHCPALVTYNTDTFESMPNPEGRYTFGASCV 296
Query: 253 VPCSQIYV 260
C Y+
Sbjct: 297 TACPYNYL 304
>AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein.
Length = 419
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 194 CQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEG-YAVSGECG 252
C AGC G D L++N S G L + TF+ + PEG Y C
Sbjct: 240 CAAGCTGPKHSDCLACLHFNHS---GICELHCPALVTYNTDTFESMPNPEGRYTFGASCV 296
Query: 253 VPCSQIYV 260
C Y+
Sbjct: 297 TACPYNYL 304
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.328 0.139 0.433
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 52,968,250
Number of Sequences: 224733
Number of extensions: 2056979
Number of successful extensions: 6581
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 6280
Number of HSP's gapped (non-prelim): 181
length of query: 411
length of database: 73,234,838
effective HSP length: 92
effective length of query: 319
effective length of database: 52,559,402
effective search space: 16766449238
effective search space used: 16766449238
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.8 bits)
S2: 66 (30.7 bits)
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