Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002722-TA|BGIBMGA002722-PA|IPR004156|Organic anion
transporter polypeptide OATP
(317 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF205074-1|AAG42206.1| 710|Homo sapiens organic anion transport... 92 2e-18
AF187816-1|AAG43446.1| 710|Homo sapiens PGE1 transporter protein. 92 2e-18
BC000585-1|AAH00585.1| 692|Homo sapiens SLCO3A1 protein protein. 91 5e-18
AB031050-1|BAA89287.1| 710|Homo sapiens organic anion transport... 91 6e-18
BC139755-1|AAI39756.1| 793|Homo sapiens SLCO5A1 protein protein. 82 2e-15
AF205075-1|AAG42207.1| 848|Homo sapiens organic anion transport... 81 5e-15
BC041095-1|AAH41095.1| 709|Homo sapiens solute carrier organic ... 79 3e-14
AB026256-1|BAA78638.1| 709|Homo sapiens organic anion transport... 79 3e-14
AB020687-1|BAA74903.2| 727|Homo sapiens KIAA0880 protein protein. 79 3e-14
U70867-1|AAC09469.1| 643|Homo sapiens prostaglandin transporter... 75 3e-13
BC051347-1|AAH51347.1| 643|Homo sapiens solute carrier organic ... 75 3e-13
BC041140-1|AAH41140.2| 643|Homo sapiens solute carrier organic ... 75 3e-13
AF056732-1|AAC62004.1| 643|Homo sapiens prostaglandin transport... 75 3e-13
AF085224-1|AAD52694.1| 579|Homo sapiens brain organic anion tra... 74 8e-13
AY273896-1|AAP33047.2| 724|Homo sapiens OATP-H protein. 73 1e-12
AK128854-1|BAC87647.1| 724|Homo sapiens 12 (SLC21A12). protein. 73 1e-12
AF401643-1|AAQ03086.1| 724|Homo sapiens organic anion transport... 73 1e-12
U21943-1|AAA87732.1| 670|Homo sapiens organic anion transportin... 73 2e-12
AJ400735-1|CAB97006.1| 670|Homo sapiens organic anion transport... 73 2e-12
AF279784-1|AAG30037.1| 670|Homo sapiens organic anion transport... 73 2e-12
BC042452-1|AAH42452.2| 408|Homo sapiens SLCO1A2 protein protein. 71 4e-12
AF205073-1|AAG42205.1| 687|Homo sapiens organic anion transport... 71 4e-12
BC015727-1|AAH15727.1| 722|Homo sapiens solute carrier organic ... 71 7e-12
AL357033-2|CAC14920.1| 722|Homo sapiens solute carrier organic ... 71 7e-12
AF205072-1|AAG42204.1| 722|Homo sapiens organic anion transport... 71 7e-12
AF187817-1|AAG43447.1| 722|Homo sapiens colon organic anion tra... 71 7e-12
AF104334-1|AAF15545.1| 661|Homo sapiens putative organic anion ... 71 7e-12
AB031051-1|BAA89288.1| 722|Homo sapiens organic anion transport... 71 7e-12
BC070264-1|AAH70264.1| 296|Homo sapiens SLCO1B3 protein protein. 66 1e-10
AY342017-1|AAQ19672.1| 702|Homo sapiens organic anion transport... 66 1e-10
AF401642-1|AAQ03085.1| 640|Homo sapiens liver-specific organic ... 66 1e-10
BC105597-1|AAI05598.1| 296|Homo sapiens Unknown (protein for IM... 66 2e-10
BC022843-1|AAH22843.1| 296|Homo sapiens Unknown (protein for IM... 66 2e-10
AY442326-1|AAS01768.1| 748|Homo sapiens organic anion transport... 66 2e-10
AY257471-1|AAP81212.1| 748|Homo sapiens liver-specific organic ... 66 2e-10
AJ400763-1|CAB97008.1| 702|Homo sapiens organic anion transport... 66 2e-10
AJ251506-1|CAB96997.1| 702|Homo sapiens organic anion transport... 66 2e-10
AF187815-1|AAG43445.1| 702|Homo sapiens liver-specific organic ... 66 2e-10
AY442325-1|AAS01767.1| 687|Homo sapiens organic anion transport... 65 4e-10
AY257470-1|AAP81211.1| 687|Homo sapiens liver-specific organic ... 65 4e-10
BC114376-1|AAI14377.1| 691|Homo sapiens solute carrier organic ... 61 4e-09
AF060500-1|AAD38323.1| 691|Homo sapiens liver specific transpor... 61 4e-09
BC105596-1|AAI05597.1| 292|Homo sapiens Unknown (protein for IM... 61 6e-09
BC070172-1|AAH70172.1| 292|Homo sapiens SLCO1B1 protein protein. 61 6e-09
BC020696-1|AAH20696.1| 296|Homo sapiens Unknown (protein for IM... 61 6e-09
AJ400749-1|CAB97007.1| 691|Homo sapiens organic anion transport... 61 6e-09
AJ132573-1|CAB62577.1| 691|Homo sapiens organic anion transport... 61 6e-09
AB026257-1|BAA78639.1| 691|Homo sapiens organic anion transport... 61 6e-09
BC022461-1|AAH22461.1| 712|Homo sapiens solute carrier organic ... 60 8e-09
AY945934-1|AAX20114.1| 691|Homo sapiens solute carrier organic ... 60 8e-09
AF260704-1|AAF70338.1| 712|Homo sapiens organic anion transport... 60 8e-09
AF205076-1|AAG42208.1| 712|Homo sapiens organic anion transport... 60 8e-09
AF205071-1|AAF20212.1| 691|Homo sapiens organic anion transport... 60 8e-09
BC054878-1|AAH54878.1| 296|Homo sapiens SLCO1B1 protein protein. 60 1e-08
AK023410-1|BAB14566.1| 583|Homo sapiens protein ( Homo sapiens ... 57 9e-08
AY273897-1|AAP33048.1| 719|Homo sapiens OATP-I protein. 36 0.25
AF505657-1|AAP30851.1| 719|Homo sapiens organic anion transport... 35 0.33
U17838-1|AAC50820.2| 1719|Homo sapiens zinc finger protein RIZ p... 30 9.3
D45132-1|BAA08110.1| 1482|Homo sapiens zinc-finger DNA-binding p... 30 9.3
AL583942-2|CAH70943.1| 1718|Homo sapiens PR domain containing 2,... 30 9.3
AL031277-4|CAI19344.1| 1540|Homo sapiens PR domain containing 2,... 30 9.3
AL031277-3|CAB37643.1| 1481|Homo sapiens PR domain containing 2,... 30 9.3
AL031277-2|CAI19343.1| 1718|Homo sapiens PR domain containing 2,... 30 9.3
AB208877-1|BAD92114.1| 1576|Homo sapiens PR-domain zinc finger p... 30 9.3
>AF205074-1|AAG42206.1| 710|Homo sapiens organic anion transporter
polypeptide-related protein 3 protein.
Length = 710
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 2/206 (0%)
Query: 112 GNNNGSLVAKLPPRSQQAHPR-SAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLY 170
G +G L R+++ + S F + ++F++ + + QG Y VSV TTLE+ +
Sbjct: 12 GGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRF 71
Query: 171 KVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLYG 230
++S G + ++ EIG + LF++Y RGHRPR I C +V+A+G + +P L
Sbjct: 72 NLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTH 131
Query: 231 TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVG 290
A +C + D + R++ T ++ L +++G+G
Sbjct: 132 QYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTA-TNMMYLLLIGAQVLLGIG 190
Query: 291 QTGIATLGIPYVDDNVGSRQSPLYMG 316
T + LG+ Y+DD+V + S LY+G
Sbjct: 191 ATPVQPLGVSYIDDHVRRKDSSLYIG 216
>AF187816-1|AAG43446.1| 710|Homo sapiens PGE1 transporter protein.
Length = 710
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 2/206 (0%)
Query: 112 GNNNGSLVAKLPPRSQQAHPR-SAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLY 170
G +G L R+++ + S F + ++F++ + + QG Y VSV TTLE+ +
Sbjct: 12 GGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRF 71
Query: 171 KVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLYG 230
++S G + ++ EIG + LF++Y RGHRPR I C +V+A+G + +P L
Sbjct: 72 NLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTH 131
Query: 231 TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVG 290
A +C + D + R++ T ++ L +++G+G
Sbjct: 132 QYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTA-TNMMYLLLIGAQVLLGIG 190
Query: 291 QTGIATLGIPYVDDNVGSRQSPLYMG 316
T + LG+ Y+DD+V + S LY+G
Sbjct: 191 ATPVQPLGVSYIDDHVRRKDSSLYIG 216
>BC000585-1|AAH00585.1| 692|Homo sapiens SLCO3A1 protein protein.
Length = 692
Score = 91.1 bits (216), Expect = 5e-18
Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 2/206 (0%)
Query: 112 GNNNGSLVAKLPPRSQQAHPR-SAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLY 170
G +G L R+++ + S F + ++F++ + + QG Y VSV TTLE+ +
Sbjct: 12 GGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRF 71
Query: 171 KVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLYG 230
++S G + ++ EIG + LF++Y RGHRPR I C +V+A+G + +P L
Sbjct: 72 NLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTH 131
Query: 231 TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVG 290
A +C + D + R++ T ++ L +++G+G
Sbjct: 132 QYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICLNRTA-TNMMYLLLIGAQVLLGIG 190
Query: 291 QTGIATLGIPYVDDNVGSRQSPLYMG 316
T + LG+ Y+DD+V + S LY+G
Sbjct: 191 ATPVQPLGVSYIDDHVRRKDSSLYIG 216
>AB031050-1|BAA89287.1| 710|Homo sapiens organic anion transporter
OATP-D protein.
Length = 710
Score = 90.6 bits (215), Expect = 6e-18
Identities = 57/206 (27%), Positives = 100/206 (48%), Gaps = 2/206 (0%)
Query: 112 GNNNGSLVAKLPPRSQQAHPR-SAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLY 170
G +G L R+++ + S F + ++F++ + + QG Y VSV TTLE+ +
Sbjct: 12 GGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRF 71
Query: 171 KVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLYG 230
++S G + ++ EIG + LF++Y RGHRPR I C +V+A+G + +P L
Sbjct: 72 NLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTH 131
Query: 231 TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVG 290
A +C + D + R++ T ++ L +++G+G
Sbjct: 132 QYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTA-TNMMYLLLIGAQVLLGIG 190
Query: 291 QTGIATLGIPYVDDNVGSRQSPLYMG 316
T + LG+ Y DD+V + S LY+G
Sbjct: 191 ATPVQPLGVSYYDDHVRRKDSSLYIG 216
>BC139755-1|AAI39756.1| 793|Homo sapiens SLCO5A1 protein protein.
Length = 793
Score = 82.2 bits (194), Expect = 2e-15
Identities = 55/183 (30%), Positives = 90/183 (49%), Gaps = 12/183 (6%)
Query: 138 TRVFMLVFLSGWVLQGMFLT-YFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLT 196
+R F++ +Q + ++ Y SV TT+E+ Y ++S +G L++ +IG + +F++
Sbjct: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
Query: 197 YLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPLCNVYN 253
Y GRG RP W+A +++A G +PH + Y + LN A LC N
Sbjct: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNAS-----APNDGLCQGGN 241
Query: 254 NFTLCNSDQIKVTETRSSITAVVIPWLFICL-LVVGVGQTGIATLGIPYVDDNVGSRQSP 312
+ ++ V LFIC +++G+G T I TLG Y+DDNV S
Sbjct: 242 STATLEPPACPKDSGGNNHWVYVA--LFICAQILIGMGSTPIYTLGPTYLDDNVKKENSS 299
Query: 313 LYM 315
LY+
Sbjct: 300 LYL 302
>AF205075-1|AAG42207.1| 848|Homo sapiens organic anion transporter
polypeptide-related protein 4 protein.
Length = 848
Score = 81.0 bits (191), Expect = 5e-15
Identities = 55/183 (30%), Positives = 90/183 (49%), Gaps = 12/183 (6%)
Query: 138 TRVFMLVFLSGWVLQGMFLT-YFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLT 196
+R F++ +Q + ++ Y SV TT+E+ Y ++S +G L++ +IG + +F++
Sbjct: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
Query: 197 YLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPLCNVYN 253
Y GRG RP W+A +++A G +PH + Y + LN A LC N
Sbjct: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNAS-----APNDGLCQGGN 241
Query: 254 NFTLCNSDQIKVTETRSSITAVVIPWLFICL-LVVGVGQTGIATLGIPYVDDNVGSRQSP 312
+ + + V LFIC +++G+G T I TLG Y+DDNV S
Sbjct: 242 --STATLEPPACPKDSGGNNHWVYLALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSS 299
Query: 313 LYM 315
LY+
Sbjct: 300 LYL 302
>BC041095-1|AAH41095.1| 709|Homo sapiens solute carrier organic
anion transporter family, member 2B1 protein.
Length = 709
Score = 78.6 bits (185), Expect = 3e-14
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 12/224 (5%)
Query: 99 VEATPEEQERLATGNNNGSLVAKLPPRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTY 158
V P+++ + G N + K P Q P S F++ ++F+L + Q M Y
Sbjct: 11 VPQVPDKETKATMGTEN-TPGGKASPDPQDVRP-SVFHNIKLFVLCHSLLQLAQLMISGY 68
Query: 159 FVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVG 218
S +T+EK + + S+T+G L + E+G +F++Y R HRPR I +++A+
Sbjct: 69 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 128
Query: 219 VIGCVMPHLLY------GTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSI 272
+ +PH + T ++ D + + P + + N + TET+
Sbjct: 129 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPAS-APSNGNCSSYTETQH-- 185
Query: 273 TAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
V+ +F+ ++GVG I GI Y+DD + SPLY+G
Sbjct: 186 -LSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLG 228
>AB026256-1|BAA78638.1| 709|Homo sapiens organic anion transporter
OATP-B protein.
Length = 709
Score = 78.6 bits (185), Expect = 3e-14
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 12/224 (5%)
Query: 99 VEATPEEQERLATGNNNGSLVAKLPPRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTY 158
V P+++ + G N + K P Q P S F++ ++F+L + Q M Y
Sbjct: 11 VPQVPDKETKATMGTEN-TPGGKASPDPQDVRP-SVFHNIKLFVLCHSLLQLAQLMISGY 68
Query: 159 FVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVG 218
S +T+EK + + S+T+G L + E+G +F++Y R HRPR I +++A+
Sbjct: 69 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 128
Query: 219 VIGCVMPHLLY------GTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSI 272
+ +PH + T ++ D + + P + + N + TET+
Sbjct: 129 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPAS-APSNGNCSSYTETQH-- 185
Query: 273 TAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
V+ +F+ ++GVG I GI Y+DD + SPLY+G
Sbjct: 186 -LSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLG 228
>AB020687-1|BAA74903.2| 727|Homo sapiens KIAA0880 protein protein.
Length = 727
Score = 78.6 bits (185), Expect = 3e-14
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 12/224 (5%)
Query: 99 VEATPEEQERLATGNNNGSLVAKLPPRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTY 158
V P+++ + G N + K P Q P S F++ ++F+L + Q M Y
Sbjct: 29 VPQVPDKETKATMGTEN-TPGGKASPDPQDVRP-SVFHNIKLFVLCHSLLQLAQLMISGY 86
Query: 159 FVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVG 218
S +T+EK + + S+T+G L + E+G +F++Y R HRPR I +++A+
Sbjct: 87 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 146
Query: 219 VIGCVMPHLLY------GTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSI 272
+ +PH + T ++ D + + P + + N + TET+
Sbjct: 147 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPAS-APSNGNCSSYTETQH-- 203
Query: 273 TAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
V+ +F+ ++GVG I GI Y+DD + SPLY+G
Sbjct: 204 -LSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLG 246
>U70867-1|AAC09469.1| 643|Homo sapiens prostaglandin transporter
hPGT protein.
Length = 643
Score = 74.9 bits (176), Expect = 3e-13
Identities = 55/187 (29%), Positives = 86/187 (45%), Gaps = 6/187 (3%)
Query: 132 RSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICT 191
RS F + +VF+L + Q ++ YF S TT+EK + + S ++G + + EI
Sbjct: 25 RSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAIL 84
Query: 192 ALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPL 248
+F++Y R HRPR I + LA G +PH L Y L + + ++ A L
Sbjct: 85 IIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRL--QAEL 142
Query: 249 CNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGS 308
C + L S T+ T+ + + + L+ G+G I GI YVDD
Sbjct: 143 CQKHWQ-DLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEP 201
Query: 309 RQSPLYM 315
SPLY+
Sbjct: 202 SNSPLYI 208
>BC051347-1|AAH51347.1| 643|Homo sapiens solute carrier organic
anion transporter family, member 2A1 protein.
Length = 643
Score = 74.9 bits (176), Expect = 3e-13
Identities = 55/187 (29%), Positives = 86/187 (45%), Gaps = 6/187 (3%)
Query: 132 RSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICT 191
RS F + +VF+L + Q ++ YF S TT+EK + + S ++G + + EI
Sbjct: 25 RSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAIL 84
Query: 192 ALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPL 248
+F++Y R HRPR I + LA G +PH L Y L + + ++ A L
Sbjct: 85 IIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRL--QAEL 142
Query: 249 CNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGS 308
C + L S T+ T+ + + + L+ G+G I GI YVDD
Sbjct: 143 CQKHWQ-DLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEP 201
Query: 309 RQSPLYM 315
SPLY+
Sbjct: 202 SNSPLYI 208
>BC041140-1|AAH41140.2| 643|Homo sapiens solute carrier organic
anion transporter family, member 2A1 protein.
Length = 643
Score = 74.9 bits (176), Expect = 3e-13
Identities = 55/187 (29%), Positives = 86/187 (45%), Gaps = 6/187 (3%)
Query: 132 RSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICT 191
RS F + +VF+L + Q ++ YF S TT+EK + + S ++G + + EI
Sbjct: 25 RSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAIL 84
Query: 192 ALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPL 248
+F++Y R HRPR I + LA G +PH L Y L + + ++ A L
Sbjct: 85 IIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRL--QAEL 142
Query: 249 CNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGS 308
C + L S T+ T+ + + + L+ G+G I GI YVDD
Sbjct: 143 CQKHWQ-DLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEP 201
Query: 309 RQSPLYM 315
SPLY+
Sbjct: 202 SNSPLYI 208
>AF056732-1|AAC62004.1| 643|Homo sapiens prostaglandin transporter
protein.
Length = 643
Score = 74.9 bits (176), Expect = 3e-13
Identities = 55/187 (29%), Positives = 86/187 (45%), Gaps = 6/187 (3%)
Query: 132 RSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICT 191
RS F + +VF+L + Q ++ YF S TT+EK + + S ++G + + EI
Sbjct: 25 RSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAIL 84
Query: 192 ALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPL 248
+F++Y R HRPR I + LA G +PH L Y L + + ++ A L
Sbjct: 85 IIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRL--QAEL 142
Query: 249 CNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGS 308
C + L S T+ T+ + + + L+ G+G I GI YVDD
Sbjct: 143 CQKHWQ-DLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEP 201
Query: 309 RQSPLYM 315
SPLY+
Sbjct: 202 SNSPLYI 208
>AF085224-1|AAD52694.1| 579|Homo sapiens brain organic anion
transporter subtype OATP1b protein.
Length = 579
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/183 (25%), Positives = 91/183 (49%), Gaps = 6/183 (3%)
Query: 137 STRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLT 196
S ++F+L +V + + +Y S+ T +E+ + + + G + + EIG + +F++
Sbjct: 16 SAKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVS 75
Query: 197 YLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPLCNVYN 253
Y + HRP I +V+ +G +PH L Y E V + G ++ + LC + N
Sbjct: 76 YFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYE-STVSVSGNLSSNSFLC-MEN 133
Query: 254 NFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPL 313
+ Q +E + +++ ++ + +V G+G+T I LGI Y++D SPL
Sbjct: 134 GTQILRPTQ-DPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPL 192
Query: 314 YMG 316
Y+G
Sbjct: 193 YIG 195
>AY273896-1|AAP33047.2| 724|Homo sapiens OATP-H protein.
Length = 724
Score = 73.3 bits (172), Expect = 1e-12
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 16/177 (9%)
Query: 141 FMLVFLSGWVLQGMFLTYFVSVT-TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLA 199
F+L + V QG+ + V+++ +T+EK Y+++S TG + ++ +I +LF+++
Sbjct: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
Query: 200 GRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCN 259
RGH+PRW+A ++ +G + +P G L + C N T C
Sbjct: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFE-------DTCVTTRNSTSCT 219
Query: 260 SDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
S T + S+ V I + L++G G T + TLG ++DD+V + +S LY+G
Sbjct: 220 SS----TSSLSNYLYVFI----LGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
>AK128854-1|BAC87647.1| 724|Homo sapiens 12 (SLC21A12). protein.
Length = 724
Score = 73.3 bits (172), Expect = 1e-12
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 16/177 (9%)
Query: 141 FMLVFLSGWVLQGMFLTYFVSVT-TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLA 199
F+L + V QG+ + V+++ +T+EK Y+++S TG + ++ +I +LF+++
Sbjct: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
Query: 200 GRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCN 259
RGH+PRW+A ++ +G + +P G L + C N T C
Sbjct: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFE-------DTCVTTRNSTSCT 219
Query: 260 SDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
S T + S+ V I + L++G G T + TLG ++DD+V + +S LY+G
Sbjct: 220 SS----TSSLSNYLYVFI----LGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
>AF401643-1|AAQ03086.1| 724|Homo sapiens organic anion transporter
OATP-M1 protein.
Length = 724
Score = 73.3 bits (172), Expect = 1e-12
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 16/177 (9%)
Query: 141 FMLVFLSGWVLQGMFLTYFVSVT-TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLA 199
F+L + V QG+ + V+++ +T+EK Y+++S TG + ++ +I +LF+++
Sbjct: 107 FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFG 166
Query: 200 GRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCN 259
RGH+PRW+A ++ +G + +P G L + C N T C
Sbjct: 167 ERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFE-------DTCVTTRNSTSCT 219
Query: 260 SDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
S T + S+ V I + L++G G T + TLG ++DD+V + +S LY+G
Sbjct: 220 SS----TSSLSNYLYVFI----LGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
>U21943-1|AAA87732.1| 670|Homo sapiens organic anion transporting
polypeptide protein.
Length = 670
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/192 (24%), Positives = 92/192 (47%), Gaps = 6/192 (3%)
Query: 128 QAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIG 187
+ H ++F+L +V + + +Y S+ T +E+ + + + G + + EIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 188 QICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAG 244
+ +F++Y + HRP I +V+ +G +PH L Y E V + G ++
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYE-STVSVSGNLSS 127
Query: 245 AAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDD 304
+ LC + N + Q +E + +++ ++ + +V G+G+T I LGI Y++D
Sbjct: 128 NSFLC-MENGTQILRPTQ-DPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIED 185
Query: 305 NVGSRQSPLYMG 316
SPLY+G
Sbjct: 186 FAKFENSPLYIG 197
>AJ400735-1|CAB97006.1| 670|Homo sapiens organic anion transporting
polypeptide 1 (OATP1) protein.
Length = 670
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/192 (24%), Positives = 92/192 (47%), Gaps = 6/192 (3%)
Query: 128 QAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIG 187
+ H ++F+L +V + + +Y S+ T +E+ + + + G + + EIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 188 QICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAG 244
+ +F++Y + HRP I +V+ +G +PH L Y E V + G ++
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYE-STVSVSGNLSS 127
Query: 245 AAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDD 304
+ LC + N + Q +E + +++ ++ + +V G+G+T I LGI Y++D
Sbjct: 128 NSFLC-MENGTQILRPTQ-DPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIED 185
Query: 305 NVGSRQSPLYMG 316
SPLY+G
Sbjct: 186 FAKFENSPLYIG 197
>AF279784-1|AAG30037.1| 670|Homo sapiens organic anion transporting
polypeptide protein.
Length = 670
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/192 (24%), Positives = 92/192 (47%), Gaps = 6/192 (3%)
Query: 128 QAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIG 187
+ H ++F+L +V + + +Y S+ T +E+ + + + G + + EIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 188 QICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAG 244
+ +F++Y + HRP I +V+ +G +PH L Y E V + G ++
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYE-STVSVSGNLSS 127
Query: 245 AAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDD 304
+ LC + N + Q +E + +++ ++ + +V G+G+T I LGI Y++D
Sbjct: 128 NSFLC-MENGTQILRPTQ-DPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIED 185
Query: 305 NVGSRQSPLYMG 316
SPLY+G
Sbjct: 186 FAKFENSPLYIG 197
>BC042452-1|AAH42452.2| 408|Homo sapiens SLCO1A2 protein protein.
Length = 408
Score = 71.3 bits (167), Expect = 4e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 6/180 (3%)
Query: 140 VFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLA 199
+F+L +V + + +Y S+ T +E+ + + + G + + EIG + +F++Y
Sbjct: 1 MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFG 60
Query: 200 GRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDGQIAGAAPLCNVYNNFT 256
+ HRP I +V+ +G +PH L Y E V + G ++ + LC + N
Sbjct: 61 TKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYE-STVSVSGNLSSNSFLC-MENGTQ 118
Query: 257 LCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ Q +E + +++ ++ + +V G+G+T I LGI Y++D SPLY+G
Sbjct: 119 ILRPTQ-DPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIG 177
>AF205073-1|AAG42205.1| 687|Homo sapiens organic anion transporter
polypeptide-related protein 2 protein.
Length = 687
Score = 71.3 bits (167), Expect = 4e-12
Identities = 54/202 (26%), Positives = 94/202 (46%), Gaps = 11/202 (5%)
Query: 121 KLPPRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTL 180
K P Q P S F++ ++F+L + Q M Y S +T+EK + + S+T+G L
Sbjct: 10 KASPDPQDVRP-SVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLL 68
Query: 181 LAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLY------GTELL 234
+ E+G +F++Y R HRPR I +++A+ + +PH + T
Sbjct: 69 ASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPE 128
Query: 235 NVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGI 294
++ D + + P + + N + TET+ V+ +F+ ++GVG I
Sbjct: 129 DMPQDFKASLCLPTTSAPAS-APSNGNCSSYTETQH---LSVVGIMFVAQTLLGVGGVPI 184
Query: 295 ATLGIPYVDDNVGSRQSPLYMG 316
GI Y+ D + SPLY+G
Sbjct: 185 QPFGISYIVDFAHNSNSPLYLG 206
>BC015727-1|AAH15727.1| 722|Homo sapiens solute carrier organic
anion transporter family, member 4A1 protein.
Length = 722
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>AL357033-2|CAC14920.1| 722|Homo sapiens solute carrier organic
anion transporter family, member 4A1 protein.
Length = 722
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>AF205072-1|AAG42204.1| 722|Homo sapiens organic anion transporter
polypeptide-related protein 1 protein.
Length = 722
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>AF187817-1|AAG43447.1| 722|Homo sapiens colon organic anion
transporter protein.
Length = 722
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>AF104334-1|AAF15545.1| 661|Homo sapiens putative organic anion
transporter protein.
Length = 661
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>AB031051-1|BAA89288.1| 722|Homo sapiens organic anion transporter
OATP-E protein.
Length = 722
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/166 (27%), Positives = 85/166 (51%), Gaps = 16/166 (9%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETR 269
++++ G + +PH G V +D + P N +C ++
Sbjct: 175 WGVLLMGTGSLVFALPHFTAGR--YEVELDAGVR-TCPA----NPGAVC-------ADST 220
Query: 270 SSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYM 315
S ++ + ++ + + GVG T + TLG+ Y+D+NV S SP+Y+
Sbjct: 221 SGLSRYQLVFM-LGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYI 265
>BC070264-1|AAH70264.1| 296|Homo sapiens SLCO1B3 protein protein.
Length = 296
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTA 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AY342017-1|AAQ19672.1| 702|Homo sapiens organic anion transporting
polypeptide 8 protein.
Length = 702
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTA 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AF401642-1|AAQ03085.1| 640|Homo sapiens liver-specific organic
anion transporter LST-3 protein.
Length = 640
Score = 66.5 bits (155), Expect = 1e-10
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 7/160 (4%)
Query: 163 TTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGC 222
TT +E+ +++ S G + + EIG + +F++Y + HRP+ I ++ G I
Sbjct: 5 TTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILM 64
Query: 223 VMPHLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIP 278
+PH G ++ N+ P C + N N ++ E +
Sbjct: 65 ALPHFFMGYYRYSKETNIDPSENSTSNLPNC-LINQMLSLNRTPSEIIERGCVKESGSHM 123
Query: 279 WLFICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
W+++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 124 WIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 163
>BC105597-1|AAI05598.1| 296|Homo sapiens Unknown (protein for
IMAGE:4715619) protein.
Length = 296
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>BC022843-1|AAH22843.1| 296|Homo sapiens Unknown (protein for
IMAGE:4734792) protein.
Length = 296
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AY442326-1|AAS01768.1| 748|Homo sapiens organic anion transporter
LST-3c protein.
Length = 748
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AY257471-1|AAP81212.1| 748|Homo sapiens liver-specific organic
anion transporter 3TM13 protein.
Length = 748
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AJ400763-1|CAB97008.1| 702|Homo sapiens organic anion transporting
polypeptide 8 (OATP8) protein.
Length = 702
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AJ251506-1|CAB96997.1| 702|Homo sapiens organic anion transporter
8 (OATP8) protein.
Length = 702
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AF187815-1|AAG43445.1| 702|Homo sapiens liver-specific organic
anion transporter protein.
Length = 702
Score = 65.7 bits (153), Expect = 2e-10
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTS 112
Query: 224 MPHLLYGTELLN--VHIDGQIAGAAPLCNVYNNFTLC-NSDQIKVTETRSSITAVVIPWL 280
+PH G + HI+ + L N TL N ++ E + W+
Sbjct: 113 LPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWI 172
Query: 281 FICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 173 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AY442325-1|AAS01767.1| 687|Homo sapiens organic anion transporter
LST-3b protein.
Length = 687
Score = 64.9 bits (151), Expect = 4e-10
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTA 112
Query: 224 MPHLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPW 279
+PH G ++ N+ P C + N N ++ E + W
Sbjct: 113 LPHFFMGYYRYSKETNIDPSENSTSNLPNC-LINQMLSLNRTPSEIIERGCVKESGSHMW 171
Query: 280 LFICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 172 IYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>AY257470-1|AAP81211.1| 687|Homo sapiens liver-specific organic
anion transporter 3TM12 protein.
Length = 687
Score = 64.9 bits (151), Expect = 4e-10
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 164 TTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCV 223
T +E+ + + S G + + EIG + +F++Y + HRP+ I +++ G I
Sbjct: 53 TQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTA 112
Query: 224 MPHLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPW 279
+PH G ++ N+ P C + N N ++ E + W
Sbjct: 113 LPHFFMGYYRYSKETNIDPSENSTSNLPNC-LINQMLSLNRTPSEIIERGCVKESGSHMW 171
Query: 280 LFICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+++ + ++ G+G+T I LGI Y+DD S LY+G
Sbjct: 172 IYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG 210
>BC114376-1|AAI14377.1| 691|Homo sapiens solute carrier organic
anion transporter family, member 1B1 protein.
Length = 691
Score = 61.3 bits (142), Expect = 4e-09
Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 5/156 (3%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYGTELLN--VHIDGQIAGAAPLCN-VYNNFTLCNSDQIKVTETRSSITAVVIPWLFI 282
H G + +ID + L + N N ++ + W+++
Sbjct: 115 HFFMGYYRYSKETNIDSSENSTSTLSTCLINQILSLNRASTEIVGKGCLKESGSYMWIYV 174
Query: 283 CL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 175 FMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AF060500-1|AAD38323.1| 691|Homo sapiens liver specific transporter
protein.
Length = 691
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNKASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>BC105596-1|AAI05597.1| 292|Homo sapiens Unknown (protein for
IMAGE:4723035) protein.
Length = 292
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>BC070172-1|AAH70172.1| 292|Homo sapiens SLCO1B1 protein protein.
Length = 292
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>BC020696-1|AAH20696.1| 296|Homo sapiens Unknown (protein for
IMAGE:4767073) protein.
Length = 296
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AJ400749-1|CAB97007.1| 691|Homo sapiens organic anion transporting
polypeptide 2 (OATP2) protein.
Length = 691
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AJ132573-1|CAB62577.1| 691|Homo sapiens organic anion transporting
polypeptide 2 protein.
Length = 691
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AB026257-1|BAA78639.1| 691|Homo sapiens organic anion transporter
OATP-C protein.
Length = 691
Score = 60.9 bits (141), Expect = 6e-09
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>BC022461-1|AAH22461.1| 712|Homo sapiens solute carrier organic
anion transporter family, member 1C1 protein.
Length = 712
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 8/199 (4%)
Query: 124 PRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAA 183
P S++ P +VF+ + + + Y S T +E+ + + S G + +
Sbjct: 30 PSSEEKQPCCG--ELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGS 87
Query: 184 TEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDG 240
EIG + F++Y + HRP+ I +++ VG + MP Y E + +
Sbjct: 88 FEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNS 147
Query: 241 QIAGAAPLCNVYNNFTLCNSDQIK-VTETRSSITAVVIPWLFICL--LVVGVGQTGIATL 297
++ + L + + ++ K + W+++ L L+ G+G+T I L
Sbjct: 148 TLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPL 207
Query: 298 GIPYVDDNVGSRQSPLYMG 316
GI Y+DD + Y+G
Sbjct: 208 GIAYLDDFASEDNAAFYIG 226
>AY945934-1|AAX20114.1| 691|Homo sapiens solute carrier organic
anion transporter family, member 1B1 protein.
Length = 691
Score = 60.5 bits (140), Expect = 8e-09
Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 5/156 (3%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYGTELLN--VHIDGQIAGAAPLCN-VYNNFTLCNSDQIKVTETRSSITAVVIPWLFI 282
H G + +ID + L + N N ++ + W+++
Sbjct: 115 HFFMGYYRYSKETNIDSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYV 174
Query: 283 CL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 175 FMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AF260704-1|AAF70338.1| 712|Homo sapiens organic anion transporting
polypeptide 14 protein.
Length = 712
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 8/199 (4%)
Query: 124 PRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAA 183
P S++ P +VF+ + + + Y S T +E+ + + S G + +
Sbjct: 30 PSSEEKQPCCG--ELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGS 87
Query: 184 TEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDG 240
EIG + F++Y + HRP+ I +++ VG + MP Y E + +
Sbjct: 88 FEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNS 147
Query: 241 QIAGAAPLCNVYNNFTLCNSDQIK-VTETRSSITAVVIPWLFICL--LVVGVGQTGIATL 297
++ + L + + ++ K + W+++ L L+ G+G+T I L
Sbjct: 148 TLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPL 207
Query: 298 GIPYVDDNVGSRQSPLYMG 316
GI Y+DD + Y+G
Sbjct: 208 GIAYLDDFASEDNAAFYIG 226
>AF205076-1|AAG42208.1| 712|Homo sapiens organic anion transporter
polypeptide-related protein 5 protein.
Length = 712
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 8/199 (4%)
Query: 124 PRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAA 183
P S++ P +VF+ + + + Y S T +E+ + + S G + +
Sbjct: 30 PSSEEKQPCCG--ELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGS 87
Query: 184 TEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLL---YGTELLNVHIDG 240
EIG + F++Y + HRP+ I +++ VG + MP Y E + +
Sbjct: 88 FEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNS 147
Query: 241 QIAGAAPLCNVYNNFTLCNSDQIK-VTETRSSITAVVIPWLFICL--LVVGVGQTGIATL 297
++ + L + + ++ K + W+++ L L+ G+G+T I L
Sbjct: 148 TLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPL 207
Query: 298 GIPYVDDNVGSRQSPLYMG 316
GI Y+DD + Y+G
Sbjct: 208 GIAYLDDFASEDNAAFYIG 226
>AF205071-1|AAF20212.1| 691|Homo sapiens organic anion transport
polypeptide 2 protein.
Length = 691
Score = 60.5 bits (140), Expect = 8e-09
Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 5/156 (3%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F++Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYGTELLN--VHIDGQIAGAAPLCN-VYNNFTLCNSDQIKVTETRSSITAVVIPWLFI 282
H G + +ID + L + N N ++ + W+++
Sbjct: 115 HFFMGYYRYSKETNIDSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYV 174
Query: 283 CL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 175 FMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>BC054878-1|AAH54878.1| 296|Homo sapiens SLCO1B1 protein protein.
Length = 296
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 7/157 (4%)
Query: 166 LEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMP 225
+E+ +++ S G + + EIG + +F+ Y + HRP+ I ++ +G + +P
Sbjct: 55 IERRFEISSSLVGFIDGSFEIGNLLVIVFVGYFGSKLHRPKLIGIGCFIMGIGGVLTALP 114
Query: 226 HLLYG----TELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLF 281
H G ++ N++ C + N N ++ + W++
Sbjct: 115 HFFMGYYRYSKETNINSSENSTSTLSTC-LINQILSLNRASPEIVGKGCLKESGSYMWIY 173
Query: 282 ICL--LVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
+ + ++ G+G+T I LG+ Y+DD S LY+G
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG 210
>AK023410-1|BAB14566.1| 583|Homo sapiens protein ( Homo sapiens
cDNA FLJ13348 fis, clone OVARC1002127, weakly similar to
SODIUM-INDEPENDENT ORGANIC ANION TRANSPORTER 2. ).
Length = 583
Score = 56.8 bits (131), Expect = 9e-08
Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 151 LQGMFLTYFVS-VTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIA 209
LQGM + F++ V T+LE+ Y + S +G + ++ +I F++Y G GH+PRW+
Sbjct: 115 LQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLG 174
Query: 210 CMMMVLAVGVIGCVMPHLLYG 230
++++ G + +PH G
Sbjct: 175 WGVLLMGTGSLVFALPHFTAG 195
>AY273897-1|AAP33048.1| 719|Homo sapiens OATP-I protein.
Length = 719
Score = 35.5 bits (78), Expect = 0.25
Identities = 33/178 (18%), Positives = 68/178 (38%), Gaps = 15/178 (8%)
Query: 139 RVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYL 198
R FM+ + + QG+ +K Y++++ L + +I A+F+ +
Sbjct: 106 RCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFY 165
Query: 199 AGRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLC 258
R + W ++ +G + C P + N G +C + C
Sbjct: 166 GDR-KKVIWFVASSFLIGLGSLLCAFPSI-------NEENKQSKVGIEDICEEIKVVSGC 217
Query: 259 NSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
S I S + + + + V G+ + LGI ++D+NV + + +Y+G
Sbjct: 218 QSSGI-------SFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLG 268
>AF505657-1|AAP30851.1| 719|Homo sapiens organic anion transporter
protein.
Length = 719
Score = 35.1 bits (77), Expect = 0.33
Identities = 33/178 (18%), Positives = 68/178 (38%), Gaps = 15/178 (8%)
Query: 139 RVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYL 198
R FM+ + + QG+ +K Y++++ L + +I A+F+ +
Sbjct: 106 RCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFY 165
Query: 199 AGRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLC 258
R + W ++ +G + C P + N G +C + C
Sbjct: 166 GDR-KKVIWXVASSFLIGLGSLLCAFPSI-------NEENKQSKVGIEDICEEIKVVSGC 217
Query: 259 NSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMG 316
S I S + + + + V G+ + LGI ++D+NV + + +Y+G
Sbjct: 218 QSSGI-------SFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLG 268
>U17838-1|AAC50820.2| 1719|Homo sapiens zinc finger protein RIZ
protein.
Length = 1719
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1528 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1585
>D45132-1|BAA08110.1| 1482|Homo sapiens zinc-finger DNA-binding
protein protein.
Length = 1482
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1327 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1384
>AL583942-2|CAH70943.1| 1718|Homo sapiens PR domain containing 2, with
ZNF domain protein.
Length = 1718
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1527 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1584
>AL031277-4|CAI19344.1| 1540|Homo sapiens PR domain containing 2, with
ZNF domain protein.
Length = 1540
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1385 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1442
>AL031277-3|CAB37643.1| 1481|Homo sapiens PR domain containing 2, with
ZNF domain protein.
Length = 1481
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1326 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1383
>AL031277-2|CAI19343.1| 1718|Homo sapiens PR domain containing 2, with
ZNF domain protein.
Length = 1718
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1527 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1584
>AB208877-1|BAD92114.1| 1576|Homo sapiens PR-domain zinc finger
protein 2 variant protein.
Length = 1576
Score = 30.3 bits (65), Expect = 9.3
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 6 IKTPCGEKSRGGRSGCTALPQPAVSNCKLQSVSDASGARTQPPHPLAYPGSDIIRLPQL 64
++TP G K+R SG T +P P+ S Q+V A+ +++ P + S IR+ ++
Sbjct: 1385 MQTPLG-KTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKI 1442
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 45,298,143
Number of Sequences: 224733
Number of extensions: 1751815
Number of successful extensions: 6860
Number of sequences better than 10.0: 64
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 6747
Number of HSP's gapped (non-prelim): 83
length of query: 317
length of database: 73,234,838
effective HSP length: 90
effective length of query: 227
effective length of database: 53,008,868
effective search space: 12033013036
effective search space used: 12033013036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 65 (30.3 bits)
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