Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002712-TA|BGIBMGA002712-PA|IPR003439|ABC transporter
related, IPR003593|AAA ATPase
(312 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette, s... 136 9e-32
AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein. 136 9e-32
AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family A... 136 9e-32
X91249-1|CAA62631.1| 674|Homo sapiens white protein. 130 6e-30
U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein. 130 6e-30
BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette, s... 130 6e-30
AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog (... 130 6e-30
AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette tr... 130 6e-30
AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette tr... 130 6e-30
AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein. 130 6e-30
AY289766-1|AAP44087.1| 655|Homo sapiens ABC transporter protein. 129 1e-29
AF103796-1|AAD09188.1| 655|Homo sapiens placenta-specific ATP-b... 129 1e-29
DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette, s... 129 1e-29
BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein. 129 1e-29
BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette, s... 129 1e-29
AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette su... 129 1e-29
AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding cass... 129 1e-29
AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2 p... 129 1e-29
AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette pr... 129 1e-29
AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistanc... 129 1e-29
AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein. 129 1e-29
AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistanc... 129 1e-29
AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette su... 129 1e-29
AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette tr... 128 2e-29
AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette su... 111 2e-24
AF320293-1|AAG40003.1| 651|Homo sapiens ABCG5 protein. 111 2e-24
AF312715-1|AAG53099.1| 651|Homo sapiens sterolin protein. 111 2e-24
AC108476-1|AAY24010.1| 549|Homo sapiens unknown protein. 111 2e-24
BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette, s... 109 9e-24
AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein. 109 9e-24
AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein. 109 9e-24
AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein. 109 9e-24
AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein. 109 9e-24
AK002040-1|BAA92050.1| 456|Homo sapiens protein ( Homo sapiens ... 102 2e-21
BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein. 97 9e-20
BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein. 97 9e-20
AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6... 97 9e-20
AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6 p... 97 9e-20
AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6 p... 97 9e-20
BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein. 89 2e-17
AF356348-1|AAL35305.1| 103|Homo sapiens breast cancer resistanc... 85 2e-16
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 82 3e-15
AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein. 82 3e-15
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 82 3e-15
Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein. 79 3e-14
AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter pro... 79 3e-14
AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette tr... 79 3e-14
AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein p... 79 3e-14
AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette su... 78 3e-14
AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette su... 78 3e-14
AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A1... 78 3e-14
U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette tran... 77 1e-13
AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9... 76 2e-13
AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens ... 76 2e-13
AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens ... 76 2e-13
AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette su... 76 2e-13
AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette su... 76 2e-13
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 74 6e-13
AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette, s... 71 7e-12
AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette, s... 71 7e-12
AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens ... 71 7e-12
AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette tr... 71 7e-12
AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1 ... 71 7e-12
AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette tr... 71 7e-12
AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein. 71 7e-12
AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding tr... 71 7e-12
AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein. 71 7e-12
X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein. 69 2e-11
U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein. 69 2e-11
DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette, s... 69 2e-11
AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein p... 69 2e-11
AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane ... 69 2e-11
AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein. 68 4e-11
BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein pr... 68 5e-11
AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5... 68 5e-11
AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette pr... 68 5e-11
AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette, ... 67 6e-11
AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2 p... 67 6e-11
AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2 p... 67 6e-11
AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette su... 67 6e-11
AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant... 67 6e-11
AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein. 67 6e-11
AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subf... 65 3e-10
AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette tr... 65 3e-10
AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette tr... 65 3e-10
AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein. 65 3e-10
AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens ... 65 3e-10
AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein. 65 3e-10
AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens ... 64 5e-10
AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens ... 64 6e-10
BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein. 63 1e-09
BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein. 62 2e-09
AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein pr... 62 2e-09
AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette, ... 61 6e-09
AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein. 61 6e-09
AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member ... 60 1e-08
AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7 p... 60 1e-08
AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transpor... 60 1e-08
AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein. 60 1e-08
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 59 2e-08
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 58 3e-08
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 58 3e-08
AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein. 55 3e-07
BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette, s... 55 4e-07
AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette, s... 55 4e-07
AK172794-1|BAD18770.1| 433|Homo sapiens protein ( Homo sapiens ... 55 4e-07
AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding casset... 54 5e-07
AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding tr... 54 9e-07
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ... 52 3e-06
EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette, s... 52 3e-06
BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette, s... 52 3e-06
BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette, s... 50 8e-06
AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette, s... 50 8e-06
AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens ... 50 8e-06
AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens ... 50 8e-06
AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette pr... 50 8e-06
AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens ... 48 6e-05
U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette prot... 47 7e-05
AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein pr... 47 7e-05
AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant p... 47 7e-05
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein. 46 1e-04
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein. 46 1e-04
BC141836-1|AAI41837.1| 693|Homo sapiens Unknown (protein for MG... 46 1e-04
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s... 46 1e-04
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s... 46 1e-04
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein. 46 1e-04
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr... 46 1e-04
BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein. 46 2e-04
AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette tr... 46 2e-04
AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug resistance-as... 46 2e-04
AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette pr... 46 2e-04
AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B ... 46 2e-04
AC069137-4|AAY24100.1| 451|Homo sapiens unknown protein. 46 2e-04
U83661-1|AAB71758.2| 1437|Homo sapiens multidrug resistance prot... 44 0.001
BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette, s... 44 0.001
BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette, s... 44 0.001
BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein. 44 0.001
BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette, s... 44 0.001
AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5 pr... 44 0.001
AY196484-1|AAO49801.1| 1394|Homo sapiens ATP-binding cassette C5... 44 0.001
AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein. 44 0.001
AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens ... 44 0.001
AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat pr... 44 0.001
AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein. 44 0.001
AF319622-1|AAN76500.1| 681|Homo sapiens P-glycoprotein protein. 44 0.001
AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette ha... 44 0.001
AF146074-1|AAD37716.1| 1437|Homo sapiens ABC protein protein. 44 0.001
AF104942-1|AAD04169.1| 1437|Homo sapiens ABC transporter MOAT-C ... 44 0.001
AF078777-1|AAD47141.1| 748|Homo sapiens ABC transporter protein. 44 0.001
AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter prot... 44 0.001
AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein. 44 0.001
AB209454-1|BAD92691.1| 1430|Homo sapiens Multidrug resistance-as... 44 0.001
AB209103-1|BAD92340.1| 799|Homo sapiens ATP-binding cassette C5... 44 0.001
AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC trans... 44 0.001
AB019002-1|BAA76608.1| 1437|Homo sapiens MRP5 protein. 44 0.001
AB005659-1|BAA22887.1| 946|Homo sapiens SMRP protein. 44 0.001
BT009918-1|AAP88920.1| 753|Homo sapiens ATP-binding cassette, s... 43 0.001
BC006323-1|AAH06323.1| 753|Homo sapiens ATP-binding cassette, s... 43 0.001
AL360179-2|CAH70565.1| 752|Homo sapiens ATP-binding cassette, s... 43 0.001
AL360179-1|CAH70564.1| 753|Homo sapiens ATP-binding cassette, s... 43 0.001
AL359545-2|CAI41573.1| 752|Homo sapiens ATP-binding cassette, s... 43 0.001
AL359545-1|CAI41574.1| 753|Homo sapiens ATP-binding cassette, s... 43 0.001
AF241887-1|AAK20173.1| 752|Homo sapiens ATP binding cassette 7 ... 43 0.001
AF133659-1|AAD33045.1| 752|Homo sapiens ATP-binding cassette 7 ... 43 0.001
AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B ... 43 0.001
AB005289-1|BAA28861.1| 752|Homo sapiens ABC transporter 7 prote... 43 0.001
AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein. 43 0.002
M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis transmemb... 41 0.005
M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic fi... 41 0.005
DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis transme... 41 0.005
DQ356257-1|ABC87053.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis transme... 41 0.005
AY848829-1|AAW33656.1| 258|Homo sapiens cystic fibrosis transme... 41 0.005
AC000061-1|AAB46340.2| 484|Homo sapiens unknown protein. 41 0.005
AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens ... 40 0.008
AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens ... 39 0.020
AY196326-1|AAO40749.1| 930|Homo sapiens truncated ABCC12 protei... 38 0.060
AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette tr... 38 0.060
AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette pr... 38 0.060
AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette pr... 38 0.060
AF395909-1|AAL79529.1| 935|Homo sapiens ATP-binding cassette pr... 38 0.060
AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette pr... 38 0.060
U91318-3|AAC15785.1| 848|Homo sapiens Gene product with similar... 37 0.10
BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette, s... 37 0.10
AY848830-1|AAW33657.1| 241|Homo sapiens cystic fibrosis transme... 37 0.10
AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic ... 37 0.10
AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein. 37 0.10
X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA) p... 36 0.14
AB208839-1|BAD92076.1| 403|Homo sapiens ATP-binding cassette, s... 36 0.14
DQ388136-1|ABD72199.1| 1321|Homo sapiens cystic fibrosis transme... 35 0.42
DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis transme... 34 0.56
AK097044-1|BAC04933.1| 199|Homo sapiens protein ( Homo sapiens ... 34 0.56
AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein. 34 0.56
AY032599-1|AAK39642.1| 1463|Homo sapiens multidrug resistance-as... 33 0.97
BC024103-1|AAH24103.1| 282|Homo sapiens ABCC10 protein protein. 33 1.3
BC021245-1|AAH21245.2| 122|Homo sapiens AFG3L1 protein protein. 33 1.3
AL359813-5|CAI23220.1| 157|Homo sapiens ATP-binding cassette, s... 33 1.3
AL359813-4|CAI23219.1| 172|Homo sapiens ATP-binding cassette, s... 33 1.3
AL359813-2|CAI23217.1| 1492|Homo sapiens ATP-binding cassette, s... 33 1.3
AL133613-1|CAB63742.1| 700|Homo sapiens hypothetical protein pr... 33 1.3
AK024446-1|BAB15736.1| 706|Homo sapiens FLJ00036 protein protein. 33 1.3
AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens ... 33 1.3
AK000002-1|BAA92227.1| 1513|Homo sapiens FLJ00002 protein protein. 33 1.3
AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein. 33 1.3
BX248518-7|CAM26017.1| 845|Homo sapiens ATP-binding cassette su... 33 1.7
BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette su... 33 1.7
BX119957-3|CAM25907.1| 845|Homo sapiens ATP-binding cassette su... 33 1.7
BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette su... 33 1.7
BX000357-8|CAI18563.1| 845|Homo sapiens ATP-binding cassette, s... 33 1.7
BX000357-6|CAI18562.1| 807|Homo sapiens ATP-binding cassette, s... 33 1.7
BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette, s... 33 1.7
BC036378-1|AAH36378.1| 633|Homo sapiens ABCC12 protein protein. 33 1.7
BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette, s... 33 1.7
BA000025-75|BAB63325.1| 807|Homo sapiens TNFalpha-inducible ATP... 33 1.7
AY040219-1|AAK76739.1| 1382|Homo sapiens ATP-binding cassette tr... 33 1.7
AL662825-8|CAI17836.1| 807|Homo sapiens ATP-binding cassette, s... 33 1.7
AL662825-7|CAI17837.1| 845|Homo sapiens ATP-binding cassette, s... 33 1.7
AL662800-8|CAI18158.1| 845|Homo sapiens ATP-binding cassette, s... 33 1.7
AL662800-7|CAI18159.1| 807|Homo sapiens ATP-binding cassette, s... 33 1.7
AF411579-1|AAL99902.1| 1344|Homo sapiens ATP-binding cassette pr... 33 1.7
AF367202-1|AAK58869.1| 1382|Homo sapiens ATP-binding cassette pr... 33 1.7
AF352582-1|AAK19755.1| 1382|Homo sapiens ATP-binding cassette tr... 33 1.7
AF027302-1|AAC70891.1| 807|Homo sapiens TNF-alpha stimulated AB... 33 1.7
AB209564-1|BAD92801.1| 593|Homo sapiens ATP-binding cassette, s... 33 1.7
AB202093-1|BAE78612.1| 807|Homo sapiens ATP-binding cassette, s... 33 1.7
AB103602-1|BAF31263.1| 807|Homo sapiens ABC50 protein protein. 33 1.7
AB088096-1|BAC54928.1| 807|Homo sapiens ATP-binding cassette, s... 33 1.7
X87344-5|CAA60785.1| 748|Homo sapiens TAP1 protein. 32 2.3
X66401-2|CAA47025.1| 748|Homo sapiens ABC-transporter protein. 32 2.3
X57522-1|CAA40741.1| 808|Homo sapiens peptide transporter protein. 32 2.3
U18236-1|AAA84437.2| 131|Homo sapiens ATP-binding cassette prot... 32 2.3
L21208-1|AAC12906.1| 748|Homo sapiens peptide transporter protein. 32 2.3
L21204-1|AAC12902.1| 748|Homo sapiens peptide transporter protein. 32 2.3
BX088556-4|CAM26263.1| 808|Homo sapiens transporter 1 ATP-bindi... 32 2.3
BC014081-1|AAH14081.1| 808|Homo sapiens transporter 1, ATP-bind... 32 2.3
AY851364-1|AAW31629.1| 131|Homo sapiens ABCB5alpha protein. 32 2.3
AY055472-2|AAL16400.1| 54|Homo sapiens ATP-binding cassette tr... 32 2.3
AY055472-1|AAL16402.1| 57|Homo sapiens ATP-binding cassette tr... 32 2.3
AL935043-6|CAI18626.1| 808|Homo sapiens transporter 1, ATP-bind... 32 2.3
AL671681-12|CAI17714.1| 808|Homo sapiens transporter 1, ATP-bin... 32 2.3
AL669918-8|CAI18140.1| 808|Homo sapiens transporter 1, ATP-bind... 32 2.3
X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug res... 32 3.0
U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific... 32 3.0
U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific... 32 3.0
L21207-1|AAC12905.1| 748|Homo sapiens peptide transporter protein. 32 3.0
L21206-1|AAC12904.1| 748|Homo sapiens peptide transporter protein. 32 3.0
L21205-1|AAC12903.1| 748|Homo sapiens peptide transporter protein. 32 3.0
AY523971-1|AAS55412.1| 748|Homo sapiens TAP1 protein. 32 3.0
AY523970-1|AAS55411.1| 748|Homo sapiens TAP1 protein. 32 3.0
AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette, s... 32 3.0
AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette, s... 32 3.0
AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance pr... 32 3.0
BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette, s... 31 3.9
BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette, s... 31 3.9
AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein. 31 3.9
AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC tran... 31 3.9
AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC tran... 31 3.9
AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein. 31 3.9
AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein. 31 3.9
BC033762-1|AAH33762.1| 506|Homo sapiens PEO1 protein protein. 31 5.2
BC013349-1|AAH13349.1| 451|Homo sapiens PEO1 protein protein. 31 5.2
AL133215-11|CAI10925.1| 684|Homo sapiens progressive external o... 31 5.2
AL133215-10|CAI10924.1| 582|Homo sapiens progressive external o... 31 5.2
AK223300-1|BAD97020.1| 703|Homo sapiens transporter 2, ATP-bind... 31 5.2
AK025485-1|BAB15148.1| 506|Homo sapiens protein ( Homo sapiens ... 31 5.2
AF292005-1|AAK69559.1| 582|Homo sapiens truncated putative T7-l... 31 5.2
AF292004-1|AAK69558.1| 684|Homo sapiens putative T7-like mitoch... 31 5.2
Z22936-1|CAA80523.1| 686|Homo sapiens TAP2E protein. 30 9.1
Z22935-1|CAA80522.1| 703|Homo sapiens TAP2B protein. 30 9.1
X87344-8|CAA60788.1| 686|Homo sapiens TAP2 protein. 30 9.1
X66401-4|CAA47027.1| 686|Homo sapiens TAP2 protein. 30 9.1
U91318-1|AAC15784.1| 401|Homo sapiens Multiple drug resistance ... 30 9.1
U07844-1|AAA79901.1| 622|Homo sapiens ABC transport protein pro... 30 9.1
M74447-1|AAA59841.1| 703|Homo sapiens PSF-2 protein. 30 9.1
L05628-1|AAB46616.1| 1531|Homo sapiens multidrug resistance-asso... 30 9.1
EF419769-1|ABN79590.1| 1531|Homo sapiens ATP-binding cassette, s... 30 9.1
BX682530-5|CAI41936.1| 653|Homo sapiens transporter 2 ATP-bindi... 30 9.1
BX682530-4|CAI41935.1| 703|Homo sapiens transporter 2 ATP-bindi... 30 9.1
BX296564-5|CAI41937.1| 653|Homo sapiens transporter 2 ATP-bindi... 30 9.1
BT009906-1|AAP88908.1| 686|Homo sapiens transporter 2, ATP-bind... 30 9.1
BC001636-1|AAH01636.1| 316|Homo sapiens Unknown (protein for IM... 30 9.1
AL935043-2|CAI18622.1| 686|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL935043-1|CAI18621.1| 653|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL671681-8|CAI17711.1| 686|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL671681-7|CAI17710.1| 653|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL669918-4|CAI18137.1| 686|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL669918-3|CAI18136.1| 653|Homo sapiens transporter 2, ATP-bind... 30 9.1
AL353692-3|CAI16236.1| 5596|Homo sapiens MDN1, midasin homolog (... 30 9.1
AL353692-2|CAI16235.1| 1181|Homo sapiens MDN1, midasin homolog (... 30 9.1
AL158813-2|CAI13203.1| 5596|Homo sapiens MDN1, midasin homolog (... 30 9.1
AL158813-1|CAI13202.1| 1181|Homo sapiens MDN1, midasin homolog (... 30 9.1
AL096678-1|CAI42279.1| 5596|Homo sapiens MDN1, midasin homolog (... 30 9.1
AK222823-1|BAD96543.1| 703|Homo sapiens transporter 2, ATP-bind... 30 9.1
AF503925-1|AAM77722.1| 5596|Homo sapiens midasin protein. 30 9.1
AF176984-1|AAD50509.1| 372|Homo sapiens TAP2 protein protein. 30 9.1
AF136750-1|AAD23601.1| 483|Homo sapiens TAP2 protein protein. 30 9.1
AF105151-1|AAD12059.1| 653|Homo sapiens Tap2 transporter isofor... 30 9.1
AF100418-1|AAD23381.1| 483|Homo sapiens TAP2 protein protein. 30 9.1
AF078671-1|AAD31384.1| 653|Homo sapiens transporter 2 isoform p... 30 9.1
AF022853-5|AAB83982.1| 1400|Homo sapiens multidrug resistance pr... 30 9.1
AF022853-4|AAB83981.1| 1456|Homo sapiens multidrug resistance pr... 30 9.1
AF022853-3|AAB83980.1| 1459|Homo sapiens multidrug resistance pr... 30 9.1
AF022853-2|AAB83983.1| 1450|Homo sapiens multidrug resistance pr... 30 9.1
AF022853-1|AAB83979.1| 1515|Homo sapiens multidrug resistance pr... 30 9.1
AB209120-1|BAD92357.1| 1439|Homo sapiens ATP-binding cassette, s... 30 9.1
AB208953-1|BAD92190.1| 704|Homo sapiens transporter 2, ATP-bind... 30 9.1
AB073779-1|BAB71769.1| 703|Homo sapiens ABC-transporter protein. 30 9.1
>BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 4 protein.
Length = 646
Score = 136 bits (329), Expect = 9e-32
Identities = 72/252 (28%), Positives = 125/252 (49%), Gaps = 4/252 (1%)
Query: 34 WTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV 93
++ E WRK + + E I+GPSGAGK+TF+ LAG +G +
Sbjct: 68 YSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQI 127
Query: 94 TINGRNVRDLTGAEI---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
+NGR T ++ + Q D+ LTV+E ++ +KL ++ K ++ ++
Sbjct: 128 LVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK-QEVKKELVTEILT 186
Query: 151 EFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKL 210
L + T A ++NP ++ DEPT+GLDS + QV+ ++K L
Sbjct: 187 ALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 246
Query: 211 SASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPA 270
+ G+ +IC++HQPS +F+ F+ + ++++G +F G + + + LHCP +NPA
Sbjct: 247 AQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPA 306
Query: 271 EFYIRAVSNHNG 282
+F I S G
Sbjct: 307 DFIIEVASGEYG 318
>AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein.
Length = 646
Score = 136 bits (329), Expect = 9e-32
Identities = 72/252 (28%), Positives = 125/252 (49%), Gaps = 4/252 (1%)
Query: 34 WTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV 93
++ E WRK + + E I+GPSGAGK+TF+ LAG +G +
Sbjct: 68 YSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQI 127
Query: 94 TINGRNVRDLTGAEI---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
+NGR T ++ + Q D+ LTV+E ++ +KL ++ K ++ ++
Sbjct: 128 LVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK-QEVKKELVTEILT 186
Query: 151 EFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKL 210
L + T A ++NP ++ DEPT+GLDS + QV+ ++K L
Sbjct: 187 ALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 246
Query: 211 SASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPA 270
+ G+ +IC++HQPS +F+ F+ + ++++G +F G + + + LHCP +NPA
Sbjct: 247 AQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPA 306
Query: 271 EFYIRAVSNHNG 282
+F I S G
Sbjct: 307 DFIIEVASGEYG 318
>AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family
ATP-binding cassette transporter protein.
Length = 627
Score = 136 bits (329), Expect = 9e-32
Identities = 72/252 (28%), Positives = 125/252 (49%), Gaps = 4/252 (1%)
Query: 34 WTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV 93
++ E WRK + + E I+GPSGAGK+TF+ LAG +G +
Sbjct: 49 YSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQI 108
Query: 94 TINGRNVRDLTGAEI---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
+NGR T ++ + Q D+ LTV+E ++ +KL ++ K ++ ++
Sbjct: 109 LVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK-QEVKKELVTEILT 167
Query: 151 EFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKL 210
L + T A ++NP ++ DEPT+GLDS + QV+ ++K L
Sbjct: 168 ALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSL 227
Query: 211 SASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPA 270
+ G+ +IC++HQPS +F+ F+ + ++++G +F G + + + LHCP +NPA
Sbjct: 228 AQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPA 287
Query: 271 EFYIRAVSNHNG 282
+F I S G
Sbjct: 288 DFIIEVASGEYG 299
>X91249-1|CAA62631.1| 674|Homo sapiens white protein.
Length = 674
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein.
Length = 638
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 40 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 98
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 99 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 157
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 158 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 217
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 218 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 277
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 278 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 312
>BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 1 protein.
Length = 666
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 80 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 138
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 139 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 197
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 198 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 257
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 258 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 317
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 318 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 352
>AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog
(ATP-binding cassette transporter 8) protein.
Length = 674
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette
transporter, sub-family G member 1 protein.
Length = 674
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 91 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 149
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 150 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 208
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 209 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 268
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 269 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 328
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 329 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 363
>AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 77 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 135
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 136 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 194
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 195 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 254
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 255 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 314
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 315 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 349
>AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 58 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 116
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 117 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 175
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 176 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 235
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 236 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 295
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 296 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 330
>AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 82 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 140
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 141 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 199
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 200 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 259
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 260 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 319
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 320 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 354
>AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 58 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 116
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 117 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 175
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 176 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 235
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 236 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 295
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 296 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 330
>AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 91 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 149
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 150 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 208
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 209 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 268
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 269 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 328
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 329 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 363
>AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 77 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 135
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 136 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 194
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 195 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 254
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 255 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 314
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 315 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 349
>AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 82 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 140
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 141 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 199
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 200 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 259
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 260 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 319
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 320 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 354
>AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein.
Length = 674
Score = 130 bits (314), Expect = 6e-30
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 5/275 (1%)
Query: 29 RNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLP 88
R+L PE WRK + + GE AI+GPSGAGK+T + LAG
Sbjct: 76 RDLSYSVPEGPW-WRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETG 134
Query: 89 FEGTVTING--RNVRDLTGAEI-VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSIL 145
+G V ING R++R + Q D+ LTV E ++ +KL + + ++
Sbjct: 135 MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKL-QEKDEGRREMV 193
Query: 146 NTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIG 205
++ L + T A ++NP ++ DEPT+GLDS + QV+
Sbjct: 194 KEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 253
Query: 206 ILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPL 265
++K L+ G+ +IC++HQPS +F+ F+ + ++++G ++ G + + L+CP
Sbjct: 254 LMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPT 313
Query: 266 NYNPAEFYIRAVSNHNGVCIKKMLENYQDQSLDCD 300
+NPA+F + S G +++ ++ D D
Sbjct: 314 YHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSD 348
>AY289766-1|AAP44087.1| 655|Homo sapiens ABC transporter protein.
Length = 655
Score = 129 bits (312), Expect = 1e-29
Identities = 83/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VIEE L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIEELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILSLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AF103796-1|AAD09188.1| 655|Homo sapiens placenta-specific
ATP-binding cassette transporter protein.
Length = 655
Score = 129 bits (312), Expect = 1e-29
Identities = 83/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VIEE L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIEELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILSLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein.
Length = 611
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLKFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette
sub-family G (WHITE) member 2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding
cassette sub-family G (WHITE) member 2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2
protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette
protein ABCG2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLKFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistance
protein protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein.
Length = 607
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistance
Protein protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette
superfamily G (White) member 2 protein.
Length = 655
Score = 129 bits (311), Expect = 1e-29
Identities = 82/245 (33%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 43 RKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAG-KCTLPFEGTVTING--RN 99
RK + + + N ++ G AI+GP+G GK++ L LA K G V ING R
Sbjct: 56 RKPVEKEILSNINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRP 114
Query: 100 VRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHV 158
+ V Q DV +LTV E L F ++L + T +N VI+E L
Sbjct: 115 ANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVA 174
Query: 159 ETXXXXXXXXXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
++ +++P IL DEPTTGLDS A+ V+ +LK++S
Sbjct: 175 DSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQ 234
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
G+ +I S+HQP IFK F+S+ L+A G L+FHG +FES HC NPA+F+
Sbjct: 235 GRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFF 294
Query: 274 IRAVS 278
+ ++
Sbjct: 295 LDIIN 299
>AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette
transporter G1 protein.
Length = 785
Score = 128 bits (310), Expect = 2e-29
Identities = 69/243 (28%), Positives = 122/243 (50%), Gaps = 4/243 (1%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING--RNVRDLTGAEI-VPQFDVFTD 117
GE AI+GPSGAGK+T + LAG +G V ING R++R + Q D+
Sbjct: 218 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLP 277
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXAT 177
LTV E ++ +KL + + ++ ++ L + T A
Sbjct: 278 HLTVQEAMMVSAHLKL-QEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIAL 336
Query: 178 SFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILL 237
++NP ++ DEPT+GLDS + QV+ ++K L+ G+ +IC++HQPS +F+ F+ + +
Sbjct: 337 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYV 396
Query: 238 MAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVSNHNGVCIKKMLENYQDQSL 297
+++G ++ G + + L+CP +NPA+F + S G +++ ++
Sbjct: 397 LSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC 456
Query: 298 DCD 300
D D
Sbjct: 457 DSD 459
>AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette
sub-family G member 2 protein.
Length = 541
Score = 111 bits (268), Expect = 2e-24
Identities = 61/176 (34%), Positives = 90/176 (51%), Gaps = 6/176 (3%)
Query: 109 VPQFDVFTDSLTVMEQLVFMTEMKLGNS-TKQPNKSILNTVIEEFKLSAHVETXXXXXXX 167
V Q DV +LTV E L F ++L + T +N VI+E L ++
Sbjct: 10 VVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFI 69
Query: 168 XXXXX-----XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH 222
+++P IL DEPTTGLDS A+ V+ +LK++S G+ +I S+H
Sbjct: 70 RGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIH 129
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
QP IFK F+S+ L+A G L+FHG +FES HC NPA+F++ ++
Sbjct: 130 QPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIIN 185
>AF320293-1|AAG40003.1| 651|Homo sapiens ABCG5 protein.
Length = 651
Score = 111 bits (268), Expect = 2e-24
Identities = 70/232 (30%), Positives = 113/232 (48%), Gaps = 12/232 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLP--FEGTVTINGRNVRDLTGAEI---VPQF 112
+ G+ I+G SG+GKTT L +++G+ F G V +NGR +R + V Q
Sbjct: 76 VESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQS 135
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D SLTV E L + + + + + V+ E LS HV
Sbjct: 136 DTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLS-HVADRLIGNYSLGGIS 194
Query: 173 X------XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A L +P++++ DEPTTGLD A+Q++ +L +L+ +IV+ ++HQP
Sbjct: 195 TGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRS 254
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
++F+ F+ I +++ G L+F GT FF CP + NP +FY+ S
Sbjct: 255 ELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTS 306
>AF312715-1|AAG53099.1| 651|Homo sapiens sterolin protein.
Length = 651
Score = 111 bits (268), Expect = 2e-24
Identities = 70/232 (30%), Positives = 113/232 (48%), Gaps = 12/232 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLP--FEGTVTINGRNVRDLTGAEI---VPQF 112
+ G+ I+G SG+GKTT L +++G+ F G V +NGR +R + V Q
Sbjct: 76 VESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQS 135
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D SLTV E L + + + + + V+ E LS HV
Sbjct: 136 DTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLS-HVADRLIGNYSLGGIS 194
Query: 173 X------XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A L +P++++ DEPTTGLD A+Q++ +L +L+ +IV+ ++HQP
Sbjct: 195 TGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRS 254
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
++F+ F+ I +++ G L+F GT FF CP + NP +FY+ S
Sbjct: 255 ELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTS 306
>AC108476-1|AAY24010.1| 549|Homo sapiens unknown protein.
Length = 549
Score = 111 bits (268), Expect = 2e-24
Identities = 70/232 (30%), Positives = 113/232 (48%), Gaps = 12/232 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLP--FEGTVTINGRNVRDLTGAEI---VPQF 112
+ G+ I+G SG+GKTT L +++G+ F G V +NGR +R + V Q
Sbjct: 76 VESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQS 135
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D SLTV E L + + + + + V+ E LS HV
Sbjct: 136 DTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLS-HVADRLIGNYSLGGIS 194
Query: 173 X------XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A L +P++++ DEPTTGLD A+Q++ +L +L+ +IV+ ++HQP
Sbjct: 195 TGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRS 254
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
++F+ F+ I +++ G L+F GT FF CP + NP +FY+ S
Sbjct: 255 ELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTS 306
>BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 8 (sterolin 2) protein.
Length = 673
Score = 109 bits (263), Expect = 9e-24
Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 11/232 (4%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCT--LPFEGTVTINGRNVRDLTGAEIVP---QF 112
+R G+ AIIG SG G+ + L + G+ G + ING+ + V Q
Sbjct: 95 VRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQH 154
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSI-LNTVIEEFKLSAHVETXXXXXXXXXXX 171
+ +LTV E L F+ +M+L + Q + + VI E +L +T
Sbjct: 155 NQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLS 214
Query: 172 XX-----XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
L NP ILI DEPT+GLDS+ A ++ L +L+ ++V+ S+HQP
Sbjct: 215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRS 274
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
DIF+ F+ +LLM G ++ G +F +I CP NPA+FY+ S
Sbjct: 275 DIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS 326
>AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein.
Length = 672
Score = 109 bits (263), Expect = 9e-24
Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 11/232 (4%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCT--LPFEGTVTINGRNVRDLTGAEIVP---QF 112
+R G+ AIIG SG G+ + L + G+ G + ING+ + V Q
Sbjct: 95 VRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQH 154
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSI-LNTVIEEFKLSAHVETXXXXXXXXXXX 171
+ +LTV E L F+ +M+L + Q + + VI E +L +T
Sbjct: 155 NQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLS 214
Query: 172 XX-----XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
L NP ILI DEPT+GLDS+ A ++ L +L+ ++V+ S+HQP
Sbjct: 215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRS 274
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
DIF+ F+ +LLM G ++ G +F +I CP NPA+FY+ S
Sbjct: 275 DIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS 326
>AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein.
Length = 673
Score = 109 bits (263), Expect = 9e-24
Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 11/232 (4%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCT--LPFEGTVTINGRNVRDLTGAEIVP---QF 112
+R G+ AIIG SG G+ + L + G+ G + ING+ + V Q
Sbjct: 95 VRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQH 154
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSI-LNTVIEEFKLSAHVETXXXXXXXXXXX 171
+ +LTV E L F+ +M+L + Q + + VI E +L +T
Sbjct: 155 NQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLS 214
Query: 172 XX-----XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
L NP ILI DEPT+GLDS+ A ++ L +L+ ++V+ S+HQP
Sbjct: 215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRS 274
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
DIF+ F+ +LLM G ++ G +F +I CP NPA+FY+ S
Sbjct: 275 DIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS 326
>AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein.
Length = 673
Score = 109 bits (263), Expect = 9e-24
Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 11/232 (4%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCT--LPFEGTVTINGRNVRDLTGAEIVP---QF 112
+R G+ AIIG SG G+ + L + G+ G + ING+ + V Q
Sbjct: 95 VRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQH 154
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSI-LNTVIEEFKLSAHVETXXXXXXXXXXX 171
+ +LTV E L F+ +M+L + Q + + VI E +L +T
Sbjct: 155 NQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLS 214
Query: 172 XX-----XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
L NP ILI DEPT+GLDS+ A ++ L +L+ ++V+ S+HQP
Sbjct: 215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRS 274
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
DIF+ F+ +LLM G ++ G +F +I CP NPA+FY+ S
Sbjct: 275 DIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS 326
>AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein.
Length = 673
Score = 109 bits (263), Expect = 9e-24
Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 11/232 (4%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCT--LPFEGTVTINGRNVRDLTGAEIVP---QF 112
+R G+ AIIG SG G+ + L + G+ G + ING+ + V Q
Sbjct: 95 VRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQH 154
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSI-LNTVIEEFKLSAHVETXXXXXXXXXXX 171
+ +LTV E L F+ +M+L + Q + + VI E +L +T
Sbjct: 155 NQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLS 214
Query: 172 XX-----XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
L NP ILI DEPT+GLDS+ A ++ L +L+ ++V+ S+HQP
Sbjct: 215 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRS 274
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVS 278
DIF+ F+ +LLM G ++ G +F +I CP NPA+FY+ S
Sbjct: 275 DIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTS 326
>AK002040-1|BAA92050.1| 456|Homo sapiens protein ( Homo sapiens
cDNA FLJ11178 fis, clone PLACE1007409, weakly similar to
WHITE PROTEIN. ).
Length = 456
Score = 102 bits (244), Expect = 2e-21
Identities = 45/115 (39%), Positives = 71/115 (61%)
Query: 180 LSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMA 239
+++P IL DEPTTGLDS A+ V+ +LK++S G+ +I S+HQP IFK F+S+ L+A
Sbjct: 4 ITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLA 63
Query: 240 EGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFYIRAVSNHNGVCIKKMLENYQD 294
G L+FHG +FES HC NPA+F++ ++ + E++++
Sbjct: 64 SGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKE 118
>BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 96.7 bits (230), Expect = 9e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 18/237 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+K E K KV K ++ D I EG+ AI+G SGAGK++ L
Sbjct: 471 EFQGKEAIRIRNVK---KEYKGKSGKVEALKGLLFD---IYEGQITAILGHSGAGKSSLL 524
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L G ++P EG+VTI +N+ ++ E + PQF+V D LTV E L ++
Sbjct: 525 NILNG-LSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKI 583
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + ++ E + + + L +PQIL+ DEP
Sbjct: 584 K-GIHLKEVEQEV-QRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEP 641
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
TTGLD ++ QV +L++ A I+ + DI + ++M+ G L G+
Sbjct: 642 TTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRK--VIMSNGRLKCAGS 696
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GPSGAGK++ +
Sbjct: 1272 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIR 1331
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 1332 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 1387
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 1388 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 1447
Query: 200 ASQV 203
Q+
Sbjct: 1448 QQQM 1451
>BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 96.7 bits (230), Expect = 9e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 18/237 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+K E K KV K ++ D I EG+ AI+G SGAGK++ L
Sbjct: 471 EFQGKEAIRIRNVK---KEYKGKSGKVEALKGLLFD---IYEGQITAILGHSGAGKSSLL 524
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L G ++P EG+VTI +N+ ++ E + PQF+V D LTV E L ++
Sbjct: 525 NILNG-LSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKI 583
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + ++ E + + + L +PQIL+ DEP
Sbjct: 584 K-GIHLKEVEQEV-QRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEP 641
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
TTGLD ++ QV +L++ A I+ + DI + ++M+ G L G+
Sbjct: 642 TTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRK--VIMSNGRLKCAGS 696
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GPSGAGK++ +
Sbjct: 1272 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIR 1331
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 1332 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 1387
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 1388 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 1447
Query: 200 ASQV 203
Q+
Sbjct: 1448 QQQM 1451
>AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6
protein.
Length = 1617
Score = 96.7 bits (230), Expect = 9e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 18/237 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+K E K KV K ++ D I EG+ AI+G SGAGK++ L
Sbjct: 471 EFQGKEAIRIRNVK---KEYKGKSGKVEALKGLLFD---IYEGQITAILGHSGAGKSSLL 524
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L G ++P EG+VTI +N+ ++ E + PQF+V D LTV E L ++
Sbjct: 525 NILNG-LSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKI 583
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + ++ E + + + L +PQIL+ DEP
Sbjct: 584 K-GIHLKEVEQEV-QRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEP 641
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
TTGLD ++ QV +L++ A I+ + DI + ++M+ G L G+
Sbjct: 642 TTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRK--VIMSNGRLKCAGS 696
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GPSGAGK++ +
Sbjct: 1272 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIR 1331
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 1332 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 1387
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 1388 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 1447
Query: 200 ASQV 203
Q+
Sbjct: 1448 QQQM 1451
>AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 96.7 bits (230), Expect = 9e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 18/237 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+K E K KV K ++ D I EG+ AI+G SGAGK++ L
Sbjct: 471 EFQGKEAIRIRNVK---KEYKGKSGKVEALKGLLFD---IYEGQITAILGHSGAGKSSLL 524
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L G ++P EG+VTI +N+ ++ E + PQF+V D LTV E L ++
Sbjct: 525 NILNG-LSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKI 583
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + ++ E + + + L +PQIL+ DEP
Sbjct: 584 K-GIHLKEVEQEV-QRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEP 641
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
TTGLD ++ QV +L++ A I+ + DI + ++M+ G L G+
Sbjct: 642 TTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRK--VIMSNGRLKCAGS 696
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GP+GAGK++ +
Sbjct: 1272 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIR 1331
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 1332 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 1387
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 1388 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 1447
Query: 200 ASQV 203
Q+
Sbjct: 1448 QQQM 1451
>AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 96.7 bits (230), Expect = 9e-20
Identities = 74/237 (31%), Positives = 117/237 (49%), Gaps = 18/237 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+K E K KV K ++ D I EG+ AI+G SGAGK++ L
Sbjct: 471 EFQGKEAIRIRNVK---KEYKGKSGKVEALKGLLFD---IYEGQITAILGHSGAGKSSLL 524
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L G ++P EG+VTI +N+ ++ E + PQF+V D LTV E L ++
Sbjct: 525 NILNG-LSVPTEGSVTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKI 583
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + ++ E + + + L +PQIL+ DEP
Sbjct: 584 K-GIHLKEVEQEV-QRILLELDMQNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEP 641
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
TTGLD ++ QV +L++ A I+ + DI + ++M+ G L G+
Sbjct: 642 TTGLDPFSRDQVWSLLRERRADHVILFSTQSMDEADILADRK--VIMSNGRLKCAGS 696
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/184 (26%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GP+GAGK++ +
Sbjct: 1272 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPNGAGKSSSIR 1331
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 1332 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 1387
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 1388 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 1447
Query: 200 ASQV 203
Q+
Sbjct: 1448 QQQM 1451
>BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.
Length = 1621
Score = 88.6 bits (210), Expect = 2e-17
Identities = 75/257 (29%), Positives = 120/257 (46%), Gaps = 19/257 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+ T E K K+ K ++ D I EG+ AI+G SGAGK+T L
Sbjct: 473 EFQGKEAIRIRNV---TKEYKGKPDKIEALKDLVFD---IYEGQITAILGHSGAGKSTLL 526
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P +G+VTI + ++ E + PQ +V D LTV E L ++
Sbjct: 527 NILSG-LSVPTKGSVTIYNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKI 585
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G ++ +K I V+ E ++ + + L +PQI + DEP
Sbjct: 586 K-GILPQEVDKEI-QRVLLELEMKNIQDVLAQNLSGGQKRKLTFGIAILGDPQIFLLDEP 643
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
T GLD ++ QV +LK+ I+ + DI + + +++G L G+
Sbjct: 644 TAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRK--VFLSQGKLKCAGSSLF 701
Query: 252 CKSFFESIDLHCPLNYN 268
K + I H L N
Sbjct: 702 LKKKW-GIGYHLSLQLN 717
Score = 60.9 bits (141), Expect = 6e-09
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 5/186 (2%)
Query: 20 FENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
F+ K II L K + + K + K + C+R+GE ++G +GAGK+T +
Sbjct: 1274 FDEKPVIIASCLRKEYAGKRKGCFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSI 1333
Query: 79 VSLAGKCTLPFEGTVTINGRNVRD-LTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNST 137
+ G T P G V + G D L PQ + +LTV + L +K
Sbjct: 1334 KVITGD-TKPTAGQVLLKGSGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVK--GLR 1390
Query: 138 KQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDS 197
K + + +++ KL +++ S L NP +++ DEP+TG+D
Sbjct: 1391 KGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1450
Query: 198 YNASQV 203
Q+
Sbjct: 1451 EGQQQM 1456
>AF356348-1|AAL35305.1| 103|Homo sapiens breast cancer resistance
protein protein.
Length = 103
Score = 85.4 bits (202), Expect = 2e-16
Identities = 38/79 (48%), Positives = 54/79 (68%)
Query: 180 LSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMA 239
+++P IL DEPTTGLDS A+ V+ +LK++S G+ +I S+HQP IFK F+S+ L+A
Sbjct: 24 ITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYPIFKLFDSLTLLA 83
Query: 240 EGNLLFHGTQDACKSFFES 258
G L+FHG +FES
Sbjct: 84 SGRLMFHGPAQEALGYFES 102
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 81.8 bits (193), Expect = 3e-15
Identities = 65/279 (23%), Positives = 118/279 (42%), Gaps = 12/279 (4%)
Query: 40 SIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
S+ ++ K V+ D + + A++G +GAGKTT + L G P GT+ ING+
Sbjct: 3846 SVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-PTSGTIIINGK 3904
Query: 99 NVR-DLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFK 153
N++ DL+ + PQ D+ D+LTV E L+ +K TK+ +N +++
Sbjct: 3905 NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVD 3964
Query: 154 LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
L+ H +F+ + ++ DEPT+G+D + + IL K
Sbjct: 3965 LTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREG 4024
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
I+ + H + + + ++ G L G K + L L P+
Sbjct: 4025 RTIIFTTHHLDEAEALSD--RVAVLQHGRLRCCGPPFCLKEAYGQ-GLRLTLTRQPS--V 4079
Query: 274 IRAVSNHNGVCIKKMLENYQDQSLDCDETGLEVNLIYKK 312
+ A + C+ +++ Y Q+ D +G E+ K
Sbjct: 4080 LEAHDLKDMACVTSLIKIYIPQAFLKDSSGSELTYTIPK 4118
Score = 47.6 bits (108), Expect = 6e-05
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 15/209 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV--TINGRNVRDLTGAEIV------ 109
I +GE ++G +GAGK+T L G+ +L + T G V DL+ A
Sbjct: 4744 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAV-DLSSAGTAGVLIGY 4802
Query: 110 -PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXX 168
PQ D + LT E L + ++ +Q + +I L AH +
Sbjct: 4803 CPQQDALDELLTGWEHLYYYCSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGG 4860
Query: 169 XXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV-IGILKKLSASGKIVICSVHQPSCD 227
A + + P IL+ DEP++G+D + + I+K++ V+ S C+
Sbjct: 4861 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECE 4920
Query: 228 IFKEFNSILLMAEGNLLFHGTQDACKSFF 256
+ +M G+ G+ K+ F
Sbjct: 4921 AL--CTRLAIMVNGSFKCLGSPQHIKNRF 4947
>AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein.
Length = 1186
Score = 81.8 bits (193), Expect = 3e-15
Identities = 65/279 (23%), Positives = 118/279 (42%), Gaps = 12/279 (4%)
Query: 40 SIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
S+ ++ K V+ D + + A++G +GAGKTT + L G P GT+ ING+
Sbjct: 106 SVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-PTSGTIIINGK 164
Query: 99 NVR-DLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFK 153
N++ DL+ + PQ D+ D+LTV E L+ +K TK+ +N +++
Sbjct: 165 NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVD 224
Query: 154 LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
L+ H +F+ + ++ DEPT+G+D + + IL K
Sbjct: 225 LTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREG 284
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
I+ + H + + + ++ G L G K + L L P+
Sbjct: 285 RTIIFTTHHLDEAEALSD--RVAVLQHGRLRCCGPPFCLKEAYGQ-GLRLTLTRQPS--V 339
Query: 274 IRAVSNHNGVCIKKMLENYQDQSLDCDETGLEVNLIYKK 312
+ A + C+ +++ Y Q+ D +G E+ K
Sbjct: 340 LEAHDLKDMACVTSLIKIYIPQAFLKDSSGSELTYTIPK 378
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 12/175 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV--TINGRNVRDLTGAEIV------ 109
I +GE ++G +GAGK+T L G+ +L + T G V DL+ A
Sbjct: 1004 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAV-DLSSAGTAGVLIGY 1062
Query: 110 -PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXX 168
PQ D + LT E L + ++ +Q + +I L AH +
Sbjct: 1063 CPQQDALDELLTGWEHLYYYCSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGG 1120
Query: 169 XXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
A + + P IL+ DEP++G+D + + + K G + + H+
Sbjct: 1121 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHR 1175
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 81.8 bits (193), Expect = 3e-15
Identities = 65/279 (23%), Positives = 118/279 (42%), Gaps = 12/279 (4%)
Query: 40 SIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
S+ ++ K V+ D + + A++G +GAGKTT + L G P GT+ ING+
Sbjct: 914 SVTKEFEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-PTSGTIIINGK 972
Query: 99 NVR-DLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFK 153
N++ DL+ + PQ D+ D+LTV E L+ +K TK+ +N +++
Sbjct: 973 NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVD 1032
Query: 154 LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
L+ H +F+ + ++ DEPT+G+D + + IL K
Sbjct: 1033 LTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREG 1092
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFFESIDLHCPLNYNPAEFY 273
I+ + H + + + ++ G L G K + L L P+
Sbjct: 1093 RTIIFTTHHLDEAEALSD--RVAVLQHGRLRCCGPPFCLKEAYGQ-GLRLTLTRQPS--V 1147
Query: 274 IRAVSNHNGVCIKKMLENYQDQSLDCDETGLEVNLIYKK 312
+ A + C+ +++ Y Q+ D +G E+ K
Sbjct: 1148 LEAHDLKDMACVTSLIKIYIPQAFLKDSSGSELTYTIPK 1186
Score = 47.6 bits (108), Expect = 6e-05
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 15/209 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV--TINGRNVRDLTGAEIV------ 109
I +GE ++G +GAGK+T L G+ +L + T G V DL+ A
Sbjct: 1813 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAV-DLSSAGTAGVLIGY 1871
Query: 110 -PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXX 168
PQ D + LT E L + ++ +Q + +I L AH +
Sbjct: 1872 CPQQDALDELLTGWEHLYYYCSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGG 1929
Query: 169 XXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV-IGILKKLSASGKIVICSVHQPSCD 227
A + + P IL+ DEP++G+D + + I+K++ V+ S C+
Sbjct: 1930 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECE 1989
Query: 228 IFKEFNSILLMAEGNLLFHGTQDACKSFF 256
+ +M G+ G+ K+ F
Sbjct: 1990 AL--CTRLAIMVNGSFKCLGSPQHIKNRF 2016
>Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.
Length = 2273
Score = 78.6 bits (185), Expect = 3e-14
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IV 109
N E + A +G +GAGKTT L L G P GTV + GR++ A +
Sbjct: 950 NITFYENQITAFLGHNGAGKTTTLSILTGLLP-PTSGTVLVGGRDIETSLDAVRQSLGMC 1008
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ ++ LTV E ++F ++K G S ++ + ++E+ L
Sbjct: 1009 PQHNILFHHLTVAEHMLFYAQLK-GKSQEEAQLE-MEAMLEDTGLHHKRNEEAQDLSGGM 1066
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIF 229
A +F+ + +++I DEPT+G+D Y+ + +L K + I++ + H D+
Sbjct: 1067 QRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLL 1126
Query: 230 KEFNSILLMAEGNLLFHGTQDACKSFF 256
+ I ++A+G L GT K+ F
Sbjct: 1127 GD--RIAIIAQGRLYCSGTPLFLKNCF 1151
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/214 (25%), Positives = 91/214 (42%), Gaps = 17/214 (7%)
Query: 53 IDNACI--REGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIV- 109
+D C+ R GE ++G +GAGKTT L G T+ G T+ G+++ LT V
Sbjct: 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVT-SGDATVAGKSI--LTNISEVH 2011
Query: 110 ------PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
PQFD + LT E L ++ G ++ K + N I+ L+ + +
Sbjct: 2012 QNMGYCPQFDAIDELLTGREHLYLYARLR-GVPAEEIEK-VANWSIKSLGLTVYADCLAG 2069
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH- 222
A + + P +++ DEPTTG+D + ++ + G+ V+ + H
Sbjct: 2070 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSHS 2129
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + +M +G GT KS F
Sbjct: 2130 MEECEAL--CTRLAIMVKGAFRCMGTIQHLKSKF 2161
>AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter protein.
Length = 2273
Score = 78.6 bits (185), Expect = 3e-14
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IV 109
N E + A +G +GAGKTT L L G P GTV + GR++ A +
Sbjct: 950 NITFYENQITAFLGHNGAGKTTTLSILTGLLP-PTSGTVLVGGRDIETSLDAVRQSLGMC 1008
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ ++ LTV E ++F ++K G S ++ + ++E+ L
Sbjct: 1009 PQHNILFHHLTVAEHMLFYAQLK-GKSQEEAQLE-MEAMLEDTGLHHKRNEEAQDLSGGM 1066
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIF 229
A +F+ + +++I DEPT+G+D Y+ + +L K + I++ + H D+
Sbjct: 1067 QRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLL 1126
Query: 230 KEFNSILLMAEGNLLFHGTQDACKSFF 256
+ I ++A+G L GT K+ F
Sbjct: 1127 GD--RIAIIAQGRLYCSGTPLFLKNCF 1151
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/214 (25%), Positives = 91/214 (42%), Gaps = 17/214 (7%)
Query: 53 IDNACI--REGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIV- 109
+D C+ R GE ++G +GAGKTT L G T+ G T+ G+++ LT V
Sbjct: 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVT-SGDATVAGKSI--LTNISEVH 2011
Query: 110 ------PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
PQFD + LT E L ++ G ++ K + N I+ L+ + +
Sbjct: 2012 QNMGYCPQFDAIDELLTGREHLYLYARLR-GVPAEEIEK-VANWSIKSLGLTVYADCLAG 2069
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH- 222
A + + P +++ DEPTTG+D + ++ + G+ V+ + H
Sbjct: 2070 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSHS 2129
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + +M +G GT KS F
Sbjct: 2130 MEECEAL--CTRLAIMVKGAFRCMGTIQHLKSKF 2161
>AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 78.6 bits (185), Expect = 3e-14
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IV 109
N E + A +G +GAGKTT L L G P GTV + GR++ A +
Sbjct: 950 NITFYENQITAFLGHNGAGKTTTLSILTGLLP-PTSGTVLVGGRDIETSLDAVRQSLGMC 1008
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ ++ LTV E ++F ++K G S ++ + ++E+ L
Sbjct: 1009 PQHNILFHHLTVAEHMLFYAQLK-GKSQEEAQLE-MEAMLEDTGLHHKRNEEAQDLSGGM 1066
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIF 229
A +F+ + +++I DEPT+G+D Y+ + +L K + I++ + H D+
Sbjct: 1067 QRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLL 1126
Query: 230 KEFNSILLMAEGNLLFHGTQDACKSFF 256
+ I ++A+G L GT K+ F
Sbjct: 1127 GD--RIAIIAQGRLYCSGTPLFLKNCF 1151
Score = 65.7 bits (153), Expect = 2e-10
Identities = 54/214 (25%), Positives = 91/214 (42%), Gaps = 17/214 (7%)
Query: 53 IDNACI--REGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIV- 109
+D C+ R GE ++G +GAGKTT L G T+ G T+ G+++ LT V
Sbjct: 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDNTVT-SGDATVAGKSI--LTNISEVH 2011
Query: 110 ------PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
PQFD + LT E L ++ G ++ K + N I+ L+ + +
Sbjct: 2012 QNMGYCPQFDAIDELLTGREHLYLYARLR-GVPAEEIEK-VANWSIKSLGLTVYADCLAG 2069
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH- 222
A + + P +++ DEPTTG+D + ++ + G+ V+ + H
Sbjct: 2070 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSHS 2129
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + +M +G GT KS F
Sbjct: 2130 MEECEAL--CTRLAIMVKGAFRCMGTIQHLKSKF 2161
>AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein
protein.
Length = 2303
Score = 78.6 bits (185), Expect = 3e-14
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IV 109
N E + A +G +GAGKTT L L G P GTV + GR++ A +
Sbjct: 980 NITFYENQITAFLGHNGAGKTTTLSILTGLLP-PTSGTVLVGGRDIETSLDAVRQSLGMC 1038
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ ++ LTV E ++F ++K G S ++ + ++E+ L
Sbjct: 1039 PQHNILFHHLTVAEHMLFYAQLK-GKSQEEAQLE-MEAMLEDTGLHHKRNEEAQDLSGGM 1096
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIF 229
A +F+ + +++I DEPT+G+D Y+ + +L K + I++ + H D+
Sbjct: 1097 QRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLL 1156
Query: 230 KEFNSILLMAEGNLLFHGTQDACKSFF 256
+ I ++A+G L GT K+ F
Sbjct: 1157 GD--RIAIIAQGRLYCSGTPLFLKNCF 1181
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/214 (25%), Positives = 91/214 (42%), Gaps = 17/214 (7%)
Query: 53 IDNACI--REGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIV- 109
+D C+ R GE ++G +GAGKTT L G T+ G T+ G+++ LT V
Sbjct: 1985 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVT-SGDATVAGKSI--LTNISEVH 2041
Query: 110 ------PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
PQFD + LT E L ++ G ++ K + N I+ L+ + +
Sbjct: 2042 QNMGYCPQFDAIDELLTGREHLYLYARLR-GVPAEEIEK-VANWSIKSLGLTVYADCLAG 2099
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH- 222
A + + P +++ DEPTTG+D + ++ + G+ V+ + H
Sbjct: 2100 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTSHS 2159
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + +M +G GT KS F
Sbjct: 2160 MEECEAL--CTRLAIMVKGAFRCMGTIQHLKSKF 2191
>AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 78.2 bits (184), Expect = 3e-14
Identities = 62/220 (28%), Positives = 101/220 (45%), Gaps = 16/220 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI +RN+ E KV + + D I EG+ AI+G +GAGK+T L
Sbjct: 384 EFHGKEAIRIRNV---IKEYNGKTGKVEALQGIFFD---IYEGQITAILGHNGAGKSTLL 437
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++ EG+ TI + ++T E + PQF+ D LTV E L ++
Sbjct: 438 NILSG-LSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKI 496
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + +I E + + + + L +PQ+L+ DEP
Sbjct: 497 K-GIQPKEVEQEV-KRIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEP 554
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
T GLD ++ +V +LK+ I+ + DI +
Sbjct: 555 TAGLDPFSRHRVWSLLKEHKVDRLILFSTQFMDEADILAD 594
Score = 62.1 bits (144), Expect = 2e-09
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 32 KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEG 91
K + +KS + + K + + C+++GE ++G +GAGK+T + + G CT P G
Sbjct: 1203 KEYYETKKSCFSTIKKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITG-CTKPTAG 1261
Query: 92 TVTING--RNVR-----DLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK-LGNSTKQPNKS 143
V + G +VR L PQ + LT+ E L +K LG K+
Sbjct: 1262 VVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLG---KEDAAL 1318
Query: 144 ILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV 203
++ ++E KL ++ S L NP +++ DEP TG+D Q+
Sbjct: 1319 SISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQM 1378
Query: 204 IGILK 208
IL+
Sbjct: 1379 WQILQ 1383
>AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 78.2 bits (184), Expect = 3e-14
Identities = 62/220 (28%), Positives = 101/220 (45%), Gaps = 16/220 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI +RN+ E KV + + D I EG+ AI+G +GAGK+T L
Sbjct: 384 EFHGKEAIRIRNV---IKEYNGKTGKVEALQGIFFD---IYEGQITAILGHNGAGKSTLL 437
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++ EG+ TI + ++T E + PQF+ D LTV E L ++
Sbjct: 438 NILSG-LSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKI 496
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + +I E + + + + L +PQ+L+ DEP
Sbjct: 497 K-GIQPKEVEQEV-KRIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEP 554
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
T GLD ++ +V +LK+ I+ + DI +
Sbjct: 555 TAGLDPFSRHRVWSLLKEHKVDRLILFSTQFMDEADILAD 594
Score = 62.1 bits (144), Expect = 2e-09
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 32 KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEG 91
K + +KS + + K + + C+++GE ++G +GAGK+T + + G CT P G
Sbjct: 1203 KEYYETKKSCFSTIKKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITG-CTKPTAG 1261
Query: 92 TVTING--RNVR-----DLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK-LGNSTKQPNKS 143
V + G +VR L PQ + LT+ E L +K LG K+
Sbjct: 1262 VVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLG---KEDAAL 1318
Query: 144 ILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV 203
++ ++E KL ++ S L NP +++ DEP TG+D Q+
Sbjct: 1319 SISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQM 1378
Query: 204 IGILK 208
IL+
Sbjct: 1379 WQILQ 1383
>AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A10
protein.
Length = 1543
Score = 78.2 bits (184), Expect = 3e-14
Identities = 62/220 (28%), Positives = 101/220 (45%), Gaps = 16/220 (7%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI +RN+ E KV + + D I EG+ AI+G +GAGK+T L
Sbjct: 384 EFHGKEAIRIRNV---IKEYNGKTGKVEALQGIFFD---IYEGQITAILGHNGAGKSTLL 437
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++ EG+ TI + ++T E + PQF+ D LTV E L ++
Sbjct: 438 NILSG-LSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKI 496
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G K+ + + +I E + + + + L +PQ+L+ DEP
Sbjct: 497 K-GIQPKEVEQEV-KRIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEP 554
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
T GLD ++ +V +LK+ I+ + DI +
Sbjct: 555 TAGLDPFSRHRVWSLLKEHKVDRLILFSTQFMDEADILAD 594
Score = 60.9 bits (141), Expect = 6e-09
Identities = 48/172 (27%), Positives = 77/172 (44%), Gaps = 14/172 (8%)
Query: 47 KPKTVIIDNA--CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR--NVRD 102
+ K + I N C+++GE ++G +GAGK+T + + G CT P G V + G +VR
Sbjct: 1216 RKKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITG-CTKPTAGVVVLQGSRASVRQ 1274
Query: 103 -----LTGAEIVPQFDVFTDSLTVMEQLVFMTEMK-LGNSTKQPNKSILNTVIEEFKLSA 156
L PQ + LT+ E L +K LG K+ ++ ++E KL
Sbjct: 1275 QHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLG---KEDAALSISRLVEALKLQE 1331
Query: 157 HVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
++ S L NP +++ DEP TG+D Q+ IL+
Sbjct: 1332 QLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQ 1383
>U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 76.6 bits (180), Expect = 1e-13
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IV 109
N E + A +G +GAGKTT L L G P GTV + GR++ A +
Sbjct: 950 NITFYENQITAFLGHNGAGKTTTLSILTGLLP-PTSGTVLVGGRDIETSLDAVRQSLGMC 1008
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ ++ LTV E ++F ++K G S ++ + ++E+ L
Sbjct: 1009 PQHNILFHHLTVAEHMLFYAQLK-GKSQEEAQLE-MEAMLEDTGLHHKRNEEAQDLSGGM 1066
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIF 229
A +F+ + +++I DEPT+G+D Y+ + +L K + I++ + H D
Sbjct: 1067 QRKLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMPTHHMDEAD-- 1124
Query: 230 KEFNSILLMAEGNLLFHGTQDACKSFF 256
+ + I ++A+G L GT K+ F
Sbjct: 1125 HQGDRIAIIAQGRLYCSGTPLFLKNCF 1151
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/214 (25%), Positives = 91/214 (42%), Gaps = 17/214 (7%)
Query: 53 IDNACI--REGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIV- 109
+D C+ R GE ++G +GAGKTT L G T+ G T+ G+++ LT V
Sbjct: 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVT-SGDATVAGKSI--LTNISEVH 2011
Query: 110 ------PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
PQFD + LT E L ++ G ++ K + N I+ L+ + +
Sbjct: 2012 QNMGYCPQFDAIDELLTGREHLYLYARLR-GVPAEEIEK-VANWSIKSLGLTVYADCLAG 2069
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH- 222
A + + P +++ DEPTTG+D + ++ + G+ V+ + H
Sbjct: 2070 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIRKGRAVVLTSHS 2129
Query: 223 QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + +M +G GT KS F
Sbjct: 2130 MEECEAL--CTRLAIMVKGAFRCMGTIQHLKSKF 2161
>AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9
protein.
Length = 1624
Score = 75.8 bits (178), Expect = 2e-13
Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI ++NLK E +V K V+ D I EG+ A++G SGAGKTT L
Sbjct: 474 EFCGKEAIRIKNLK---KEYAGKCERVEALKGVVFD---IYEGQITALLGHSGAGKTTLL 527
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P G+VT+ + + E + PQ +V LTV E L ++
Sbjct: 528 NILSG-LSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKI 586
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G + K + V++E ++ + + L +PQ+L+ DEP
Sbjct: 587 K-GILPHEVEKEV-QRVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEP 644
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICS 220
T GLD + ++ +LK+ S ++++ S
Sbjct: 645 TAGLDPLSRHRIWNLLKE-GKSDRVILFS 672
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/207 (22%), Positives = 92/207 (44%), Gaps = 9/207 (4%)
Query: 6 LDKVTVTIQVLLDEFENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNA--CIREGE 62
++++ + + +F+ II L K + ++K+ + K + KT+ N C+++GE
Sbjct: 1263 MERMRTVNAMAVRDFDETPVIIASCLRKEYAGKKKNCFSK--RKKTIATRNVSFCVKKGE 1320
Query: 63 FAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTG-AEIVPQFDVFTDSLTV 121
++G +GAGK+T + + G T P G V + G + G PQ + +LTV
Sbjct: 1321 VIGLLGHNGAGKSTTIKMITGD-TKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTV 1379
Query: 122 MEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLS 181
+ L +K K + +++ KL ++ S L
Sbjct: 1380 RQHLEVYAAVK--GLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKLRFVLSILG 1437
Query: 182 NPQILICDEPTTGLDSYNASQVIGILK 208
NP +++ DEP+TG+D Q+ +++
Sbjct: 1438 NPSVVLLDEPSTGMDPEGQQQMWQVIR 1464
>AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens
cDNA FLJ90010 fis, clone HEMBA1000349, weakly similar to
ATP-BINDING CASSETTE TRANSPORTER 1. ).
Length = 483
Score = 75.8 bits (178), Expect = 2e-13
Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI ++NLK E +V K V+ D I EG+ A++G SGAGKTT L
Sbjct: 101 EFCGKEAIRIKNLK---KEYAGKCERVEALKGVVFD---IYEGQITALLGHSGAGKTTLL 154
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P G+VT+ + + E + PQ +V LTV E L ++
Sbjct: 155 NILSG-LSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKI 213
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G + K + V++E ++ + + L +PQ+L+ DEP
Sbjct: 214 K-GILPHEVEKEV-QRVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEP 271
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICS 220
T GLD + ++ +LK+ S ++++ S
Sbjct: 272 TAGLDPLSRHRIWNLLKE-GKSDRVILFS 299
>AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens
cDNA FLJ32506 fis, clone SMINT1000042, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 3. ).
Length = 856
Score = 75.8 bits (178), Expect = 2e-13
Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI ++NLK E +V K V+ D I EG+ A++G SGAGKTT L
Sbjct: 474 EFCGKEAIRIKNLK---KEYAGKCERVEALKGVVFD---IYEGQITALLGHSGAGKTTLL 527
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P G+VT+ + + E + PQ +V LTV E L ++
Sbjct: 528 NILSG-LSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKI 586
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G + K + V++E ++ + + L +PQ+L+ DEP
Sbjct: 587 K-GILPHEVEKEV-QRVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEP 644
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICS 220
T GLD + ++ +LK+ S ++++ S
Sbjct: 645 TAGLDPLSRHRIWNLLKE-GKSDRVILFS 672
>AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 75.8 bits (178), Expect = 2e-13
Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI ++NLK E +V K V+ D I EG+ A++G SGAGKTT L
Sbjct: 474 EFCGKEAIRIKNLK---KEYAGKCERVEALKGVVFD---IYEGQITALLGHSGAGKTTLL 527
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P G+VT+ + + E + PQ +V LTV E L ++
Sbjct: 528 NILSG-LSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKI 586
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G + K + V++E ++ + + L +PQ+L+ DEP
Sbjct: 587 K-GILPHEVEKEV-QRVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEP 644
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICS 220
T GLD + ++ +LK+ S ++++ S
Sbjct: 645 TAGLDPLSRHRIWNLLKE-GKSDRVILFS 672
Score = 60.5 bits (140), Expect = 7e-09
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 5/205 (2%)
Query: 6 LDKVTVTIQVLLDEFENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFA 64
++++ + + +F+ II L K + ++K+ + K K + C+++GE
Sbjct: 1263 MERMRTVNAMAVRDFDETPVIIASCLRKEYAGKKKNCFSKRKKKIATRNVSFCVKKGEVI 1322
Query: 65 AIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTG-AEIVPQFDVFTDSLTVME 123
++G +GAGK+T + + G T P G V + G + G PQ + +LTV +
Sbjct: 1323 GLLGHNGAGKSTTIKMITGD-TKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTVRQ 1381
Query: 124 QLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNP 183
L +K K + +++ KL ++ S L NP
Sbjct: 1382 HLEVYAAVK--GLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKLCFVLSILGNP 1439
Query: 184 QILICDEPTTGLDSYNASQVIGILK 208
+++ DEP+TG+D Q+ +++
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIR 1464
>AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 75.8 bits (178), Expect = 2e-13
Identities = 61/209 (29%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF K+AI ++NLK E +V K V+ D I EG+ A++G SGAGKTT L
Sbjct: 474 EFCGKEAIRIKNLK---KEYAGKCERVEALKGVVFD---IYEGQITALLGHSGAGKTTLL 527
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAEIV-------PQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P G+VT+ + + E + PQ +V LTV E L ++
Sbjct: 528 NILSG-LSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKI 586
Query: 132 KLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEP 191
K G + K + V++E ++ + + L +PQ+L+ DEP
Sbjct: 587 K-GILPHEVEKEV-QRVVQELEMENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEP 644
Query: 192 TTGLDSYNASQVIGILKKLSASGKIVICS 220
T GLD + ++ +LK+ S ++++ S
Sbjct: 645 TAGLDPLSRHRIWNLLKE-GKSDRVILFS 672
Score = 60.5 bits (140), Expect = 7e-09
Identities = 45/205 (21%), Positives = 89/205 (43%), Gaps = 5/205 (2%)
Query: 6 LDKVTVTIQVLLDEFENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFA 64
++++ + + +F+ II L K + ++K+ + K K + C+++GE
Sbjct: 1263 MERMRTVNAMAVRDFDETPVIIASCLRKEYAGKKKNCFSKRKKKIATRNVSFCVKKGEVI 1322
Query: 65 AIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTG-AEIVPQFDVFTDSLTVME 123
++G +GAGK+T + + G T P G V + G + G PQ + +LTV +
Sbjct: 1323 GLLGHNGAGKSTTIKMITGD-TKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTVRQ 1381
Query: 124 QLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNP 183
L +K K + +++ KL ++ S L NP
Sbjct: 1382 HLEVYAAVK--GLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKLCFVLSILGNP 1439
Query: 184 QILICDEPTTGLDSYNASQVIGILK 208
+++ DEP+TG+D Q+ +++
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIR 1464
>AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens
cDNA FLJ46729 fis, clone TRACH3019370, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 851
Score = 74.1 bits (174), Expect = 6e-13
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 7/176 (3%)
Query: 40 SIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
S+ ++ K V+ D + + A++G +GAGKTT + L G P GT+ ING+
Sbjct: 601 SVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-PTSGTIIINGK 659
Query: 99 NVR-DLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFK 153
N++ DL+ + PQ D+ D+LTV E L+ +K TK+ +N +++
Sbjct: 660 NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVD 719
Query: 154 LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
L+ H +F+ + ++ DEPT+G+D + + IL K
Sbjct: 720 LTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLK 775
>AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberisiae) protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberog, Drosophila) protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ27304 fis, clone TMS05176, highly similar to
ATP-binding cassette, sub-family A, member 1. ).
Length = 546
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 99 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 157
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 158 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 216
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 217 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 274
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 275 IAIISHGKLCCVGS 288
>AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette
transporter-1 (ABC-1) protein.
Length = 2201
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 865 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 923
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 924 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 982
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 983 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1040
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1041 IAIISHGKLCCVGS 1054
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1856 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1911
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1912 LNRNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 1969
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 1970 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2029
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2030 VVKEGRSVVLTSH 2042
>AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1
sub-family A member 1 protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSKKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette
transporter 1 protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNXNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding
transporter 1 protein.
Length = 2201
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 865 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 923
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 924 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 982
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 983 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1040
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1041 IAIISHGKLCCVGS 1054
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1856 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1911
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1912 LNRNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 1969
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 1970 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2029
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2030 VVKEGRSVVLTSH 2042
>AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein.
Length = 2261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 9/194 (4%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
EG+ + +G +GAGKTT + L G P GT I G+++R + PQ +V
Sbjct: 925 EGQITSFLGHNGAGKTTTMSILTGLFP-PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNV 983
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E + F +K G S K + ++ S+ +++
Sbjct: 984 LFDMLTVEEHIWFYARLK-GLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ +++I DEPT G+D Y+ + +L K I++ + H D+ +
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGD--R 1100
Query: 235 ILLMAEGNLLFHGT 248
I +++ G L G+
Sbjct: 1101 IAIISHGKLCCVGS 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 1916 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 1971
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVI 149
+N N+ ++ PQFD T+ LT E + F ++ G K+ K + I
Sbjct: 1972 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR-GVPEKEVGK-VGEWAI 2029
Query: 150 EEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKK 209
+ L + E A + + P ++ DEPTTG+D +
Sbjct: 2030 RKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALS 2089
Query: 210 LSASGKIVICSVH 222
+ G+ V+ + H
Sbjct: 2090 VVKEGRSVVLTSH 2102
>X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.
Length = 1704
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Query: 20 FENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFL 78
FE + +V +K+ ++R K + + D N + EG+ ++G +GAGKTT L
Sbjct: 519 FEAEPEDLVAGIKI--KHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTL 576
Query: 79 VSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKL 133
L G P G I+G + +D+ + PQ D+ D+LTV E L F ++K
Sbjct: 577 SMLTGLFP-PTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKG 635
Query: 134 GNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTT 193
+ K P + + ++ L + + ++ ++LI DEPT+
Sbjct: 636 LSRQKCPEE--VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTS 693
Query: 194 GLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
G+D+ + + +L++ + IV+ + D+ + I +MA+G L
Sbjct: 694 GMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGD--RIAIMAKGEL 741
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 11/207 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IVPQF 112
+++GE ++G +GAGKTT L G+ +L G + G + G PQF
Sbjct: 1406 VQKGECFGLLGFNGAGKTTTFKMLTGEESLT-SGDAFVGGHRISSDVGKVRQRIGYCPQF 1464
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D D +T E LV ++ G + + NT + L H
Sbjct: 1465 DALLDHMTGREMLVMYARLR-GIPERHIGACVENT-LRGLLLEPHANKLVRTYSGGNKRK 1522
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKE 231
+ + P ++ DEP+TG+D + + + SGK +I + H C+
Sbjct: 1523 LSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEAL-- 1580
Query: 232 FNSILLMAEGNLLFHGTQDACKSFFES 258
+ +M +G G+ KS F S
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGS 1607
>U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.
Length = 1704
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Query: 20 FENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFL 78
FE + +V +K+ ++R K + + D N + EG+ ++G +GAGKTT L
Sbjct: 519 FEAEPEDLVAGIKI--KHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTL 576
Query: 79 VSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKL 133
L G P G I+G + +D+ + PQ D+ D+LTV E L F ++K
Sbjct: 577 SMLTGLFP-PTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKG 635
Query: 134 GNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTT 193
+ K P + + ++ L + + ++ ++LI DEPT+
Sbjct: 636 LSRQKCPEE--VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTS 693
Query: 194 GLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
G+D+ + + +L++ + IV+ + D+ + I +MA+G L
Sbjct: 694 GMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGD--RIAIMAKGEL 741
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 11/207 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IVPQF 112
+++GE ++G +GAGKTT L G+ +L G + G + G PQF
Sbjct: 1406 VQKGECFGLLGFNGAGKTTTFKMLTGEESLT-SGDAFVGGHRISSDVGKVRQRIGYCPQF 1464
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D D +T E LV ++ G + + NT + L H
Sbjct: 1465 DALLDHMTGREMLVMYARLR-GIPERHIGACVENT-LRGLLLEPHANKLVRTYSGGNKRK 1522
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKE 231
+ + P ++ DEP+TG+D + + + SGK +I + H C+
Sbjct: 1523 LSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEAL-- 1580
Query: 232 FNSILLMAEGNLLFHGTQDACKSFFES 258
+ +M +G G+ KS F S
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGS 1607
>DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), member 3 protein.
Length = 1704
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Query: 20 FENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFL 78
FE + +V +K+ ++R K + + D N + EG+ ++G +GAGKTT L
Sbjct: 519 FEAEPEDLVAGIKI--KHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTL 576
Query: 79 VSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKL 133
L G P G I+G + +D+ + PQ D+ D+LTV E L F ++K
Sbjct: 577 SMLTGLFP-PTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKG 635
Query: 134 GNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTT 193
+ K P + + ++ L + + ++ ++LI DEPT+
Sbjct: 636 LSRQKCPEE--VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTS 693
Query: 194 GLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
G+D+ + + +L++ + IV+ + D+ + I +MA+G L
Sbjct: 694 GMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGD--RIAIMAKGEL 741
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 11/207 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IVPQF 112
+++GE ++G +GAGKTT L G+ +L G + G + G PQF
Sbjct: 1406 VQKGECFGLLGFNGAGKTTTFKMLTGEESLT-SGDAFVGGHRISSDVGKVRQRIGYCPQF 1464
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D D +T E LV ++ G + + NT + L H
Sbjct: 1465 DALLDHMTGREMLVMYARLR-GIPERHIGACVENT-LRGLLLEPHANKLVRTYSGGNKRK 1522
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKE 231
+ + P ++ DEP+TG+D + + + SGK +I + H C+
Sbjct: 1523 LSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEAL-- 1580
Query: 232 FNSILLMAEGNLLFHGTQDACKSFFES 258
+ +M +G G+ KS F S
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGS 1607
>AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein
protein.
Length = 1708
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Query: 20 FENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFL 78
FE + +V +K+ ++R K + + D N + EG+ ++G +GAGKTT L
Sbjct: 523 FEAEPEDLVAGIKI--KHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTL 580
Query: 79 VSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKL 133
L G P G I+G + +D+ + PQ D+ D+LTV E L F ++K
Sbjct: 581 SMLTGLFP-PTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKG 639
Query: 134 GNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTT 193
+ K P + + ++ L + + ++ ++LI DEPT+
Sbjct: 640 LSRQKCPEE--VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTS 697
Query: 194 GLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
G+D+ + + +L++ + IV+ + D+ + I +MA+G L
Sbjct: 698 GMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGD--RIAIMAKGEL 745
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 11/207 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IVPQF 112
+++GE ++G +GAGKTT L G+ +L G + G + G PQF
Sbjct: 1410 VQKGECFGLLGFNGAGKTTTFKMLTGEESLT-SGDAFVGGHRISSDVGKVRQRIGYCPQF 1468
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D D +T E LV ++ G + + NT + L H
Sbjct: 1469 DALLDHMTGREMLVMYARLR-GIPERHIGACVENT-LRGLLLEPHANKLVRTYSGGNKRK 1526
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKE 231
+ + P ++ DEP+TG+D + + + SGK +I + H C+
Sbjct: 1527 LSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEAL-- 1584
Query: 232 FNSILLMAEGNLLFHGTQDACKSFFES 258
+ +M +G G+ KS F S
Sbjct: 1585 CTRLAIMVQGQFKCLGSPQHLKSKFGS 1611
>AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane
specific ATP-binding cassette protein protein.
Length = 1704
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/230 (24%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Query: 20 FENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIID-NACIREGEFAAIIGPSGAGKTTFL 78
FE + +V +K+ ++R K + + D N + EG+ ++G +GAGKTT L
Sbjct: 519 FEAEPEDLVAGIKI--KHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLGHNGAGKTTTL 576
Query: 79 VSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLVFMTEMKL 133
L G P G I+G + +D+ + PQ D+ D+LTV E L F ++K
Sbjct: 577 SMLTGLFP-PTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKG 635
Query: 134 GNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTT 193
+ K P + + ++ L + + ++ ++LI DEPT+
Sbjct: 636 LSRQKCPEE--VKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSKVLILDEPTS 693
Query: 194 GLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
G+D+ + + +L++ + IV+ + D+ + I +MA+G L
Sbjct: 694 GMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGD--RIAIMAKGEL 741
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 11/207 (5%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE-----IVPQF 112
+++GE ++G +GAGKTT L G+ +L G + G + G PQF
Sbjct: 1406 VQKGECFGLLGFNGAGKTTTFKMLTGEESLT-SGDAFVGGHRISSDVGKVRQRIGYCPQF 1464
Query: 113 DVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXX 172
D D +T E LV ++ G + + NT + L H
Sbjct: 1465 DALLDHMTGREMLVMYARLR-GIPERHIGACVENT-LRGLLLEPHANKLVRTYSGGNKRK 1522
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKE 231
+ + P ++ DEP+TG+D + + + SGK +I + H C+
Sbjct: 1523 LSTGIALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEAL-- 1580
Query: 232 FNSILLMAEGNLLFHGTQDACKSFFES 258
+ +M +G G+ KS F S
Sbjct: 1581 CTRLAIMVQGQFKCLGSPQHLKSKFGS 1607
>AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein.
Length = 925
Score = 68.1 bits (159), Expect = 4e-11
Identities = 67/253 (26%), Positives = 112/253 (44%), Gaps = 26/253 (10%)
Query: 13 IQVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
I+ + EF K+AI + ++ T +K V + + D I EG+ A++G SG
Sbjct: 465 IEPVSSEFVGKEAIRISGIRK-TYRKKG--ENVEALRNLSFD---IYEGQITALLGHSGT 518
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-------EIVPQFDVFTDSLTVMEQL 125
GK+T + L G C P +G +I G V ++ I PQ D+ D LTV E L
Sbjct: 519 GKSTLMNILCGLCP-PSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENL 577
Query: 126 VFMTEMK---LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSN 182
+ +K N ++ K +L+ ++ K + + L N
Sbjct: 578 SILASIKGIPANNIIQEVQKVLLDLDMQTIK-----DNQAKKLSGGQKRKLSLGIAVLGN 632
Query: 183 PQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEG 241
P+IL+ DEPT G+D + V +LK A+ ++ + S H DI + +++ ++G
Sbjct: 633 PKILLLDEPTAGMDPCSRHIVWNLLKYRKAN-RVTVFSTHFMDEADILADRKAVI--SQG 689
Query: 242 NLLFHGTQDACKS 254
L G+ KS
Sbjct: 690 MLKCVGSSMFLKS 702
>BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein
protein.
Length = 431
Score = 67.7 bits (158), Expect = 5e-11
Identities = 67/253 (26%), Positives = 112/253 (44%), Gaps = 26/253 (10%)
Query: 13 IQVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
I+ + EF K+AI + ++ T +K V + + D I EG+ A++G SG
Sbjct: 136 IEPVSSEFVGKEAIRISGIQK-TYRKKG--ENVEALRNLSFD---IYEGQITALLGHSGT 189
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-------EIVPQFDVFTDSLTVMEQL 125
GK+T + L G C P +G +I G V ++ I PQ D+ D LTV E L
Sbjct: 190 GKSTLMNILCGLCP-PSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENL 248
Query: 126 VFMTEMK---LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSN 182
+ +K N ++ K +L+ ++ K + + L N
Sbjct: 249 SILASIKGIPANNIIQEVQKVLLDLDMQTIK-----DNQAKKLSGGQKRKLSLGIAVLGN 303
Query: 183 PQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEG 241
P+IL+ DEPT G+D + V +LK A+ ++ + S H DI + +++ ++G
Sbjct: 304 PKILLLDEPTAGMDPCSRHIVWNLLKYRKAN-RVTVFSTHFMDEADILADRKAVI--SQG 360
Query: 242 NLLFHGTQDACKS 254
L G+ KS
Sbjct: 361 MLKCVGSSMFLKS 373
>AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5
protein.
Length = 1642
Score = 67.7 bits (158), Expect = 5e-11
Identities = 67/253 (26%), Positives = 112/253 (44%), Gaps = 26/253 (10%)
Query: 13 IQVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
I+ + EF K+AI + ++ T +K V + + D I EG+ A++G SG
Sbjct: 465 IEPVSSEFVGKEAIRISGIQK-TYRKKG--ENVEALRNLSFD---IYEGQITALLGHSGT 518
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-------EIVPQFDVFTDSLTVMEQL 125
GK+T + L G C P +G +I G V ++ I PQ D+ D LTV E L
Sbjct: 519 GKSTLMNILCGLCP-PSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENL 577
Query: 126 VFMTEMK---LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSN 182
+ +K N ++ K +L+ ++ K + + L N
Sbjct: 578 SILASIKGIPANNIIQEVQKVLLDLDMQTIK-----DNQAKKLSGGQKRKLSLGIAVLGN 632
Query: 183 PQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEG 241
P+IL+ DEPT G+D + V +LK A+ ++ + S H DI + +++ ++G
Sbjct: 633 PKILLLDEPTAGMDPCSRHIVWNLLKYRKAN-RVTVFSTHFMDEADILADRKAVI--SQG 689
Query: 242 NLLFHGTQDACKS 254
L G+ KS
Sbjct: 690 MLKCVGSSMFLKS 702
Score = 64.9 bits (151), Expect = 3e-10
Identities = 63/245 (25%), Positives = 100/245 (40%), Gaps = 14/245 (5%)
Query: 21 ENKDAIIVRNLKVWTPEEKS--IWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
E K +I+V NL ++K + RKV K T I + C+++GE ++GP+GAGK+T +
Sbjct: 1285 EEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYI-SFCVKKGEILGLLGPNGAGKSTII 1343
Query: 79 VSLAGKCTLPFEGTVTI------NGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
L G P G V + + L PQ + T+ E +K
Sbjct: 1344 NILVGDIE-PTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVK 1402
Query: 133 LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPT 192
G S K +++ + L H++ A S L NPQI + DEP+
Sbjct: 1403 -GMSASD-MKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 1460
Query: 193 TGLDSYNASQVIGILKKLSASGK-IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
TG+D + ++ + K I + H + + + +M G L GT
Sbjct: 1461 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYME-EAEAVCDRVAIMVSGQLRCIGTVQH 1519
Query: 252 CKSFF 256
KS F
Sbjct: 1520 LKSKF 1524
>AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette
protein protein.
Length = 1642
Score = 67.7 bits (158), Expect = 5e-11
Identities = 67/253 (26%), Positives = 112/253 (44%), Gaps = 26/253 (10%)
Query: 13 IQVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
I+ + EF K+AI + ++ T +K V + + D I EG+ A++G SG
Sbjct: 465 IEPVSSEFVGKEAIRISGIQK-TYRKKG--ENVEALRNLSFD---IYEGQITALLGHSGT 518
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-------EIVPQFDVFTDSLTVMEQL 125
GK+T + L G C P +G +I G V ++ I PQ D+ D LTV E L
Sbjct: 519 GKSTLMNILCGLCP-PSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENL 577
Query: 126 VFMTEMK---LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSN 182
+ +K N ++ K +L+ ++ K + + L N
Sbjct: 578 SILASIKGIPANNIIQEVQKVLLDLDMQTIK-----DNQAKKLSGGQKRKLSLGIAVLGN 632
Query: 183 PQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEG 241
P+IL+ DEPT G+D + V +LK A+ ++ + S H DI + +++ ++G
Sbjct: 633 PKILLLDEPTAGMDPCSRHIVWNLLKYRKAN-RVTVFSTHFMDEADILADRKAVI--SQG 689
Query: 242 NLLFHGTQDACKS 254
L G+ KS
Sbjct: 690 MLKCVGSSMFLKS 702
Score = 64.9 bits (151), Expect = 3e-10
Identities = 62/245 (25%), Positives = 101/245 (41%), Gaps = 14/245 (5%)
Query: 21 ENKDAIIVRNLKVWTPEEKS--IWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
E K +I+V NL ++K + RKV K T I + C+++GE ++GP+GAGK+T +
Sbjct: 1285 EEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYI-SFCVKKGEILGLLGPNGAGKSTII 1343
Query: 79 VSLAGKCTLPFEGTVTI------NGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
L G P G + + + + L PQ + T+ E +K
Sbjct: 1344 NILVGDIE-PTSGQIFLGDYSSESSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVK 1402
Query: 133 LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPT 192
G S K +++ + L H++ A S L NPQI + DEP+
Sbjct: 1403 -GMSASD-MKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 1460
Query: 193 TGLDSYNASQVIGILKKLSASGK-IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
TG+D + ++ + K I + H + + + +M G L GT
Sbjct: 1461 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYME-EAEAVCDRVAIMVSGQLRCIGTVQH 1519
Query: 252 CKSFF 256
KS F
Sbjct: 1520 LKSKF 1524
>AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 2435
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 1016 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 1074
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 1075 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1132
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 1133 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 1190
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 1191 IAIISHGKL 1199
Score = 62.9 bits (146), Expect = 1e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 2039 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRPGECFGLLGVNG 2090
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 2091 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 2149
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 2150 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 2207
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 2208 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 2265
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 2266 LGSIQHLKNRF 2276
>AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 1075
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 1076 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 1191
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 1192 IAIISHGKL 1200
Score = 62.1 bits (144), Expect = 2e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 2040 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRLGECFGLLGVNG 2091
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 2092 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 2150
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 2151 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 2208
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 2209 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 2266
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 2267 LGSIQHLKNRF 2277
>AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 1075
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 1076 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 1191
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 1192 IAIISHGKL 1200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 2040 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRPGECFGLLGVNG 2091
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 2092 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 2150
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 2151 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 2208
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 2209 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 2266
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 2267 LGSIQHLKNRF 2277
>AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette
sub-family A member 2 protein.
Length = 2436
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 1075
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 1076 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 1191
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 1192 IAIISHGKL 1200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 2040 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRPGECFGLLGVNG 2091
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 2092 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 2150
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 2151 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 2208
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 2209 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 2266
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 2267 LGSIQHLKNRF 2277
>AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant 1
protein.
Length = 1440
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 366 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 424
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 425 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 482
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 483 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 540
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 541 IAIISHGKL 549
>AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.
Length = 1771
Score = 67.3 bits (157), Expect = 6e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRD-----LTGAEIVPQFDV 114
E + + +G +GAGKTT + L G P G+ TI G ++R + PQ +V
Sbjct: 352 ENQVVSFLGHNGAGKTTTMSILTGLFP-PTSGSATIYGHDIRTEMDEIRKNLGMCPQHNV 410
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXX 174
D LTV E L F + +K + ++ + ++ +IE+ +LS +
Sbjct: 411 LFDRLTVEEHLWFYSRLK--SMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 468
Query: 175 XATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNS 234
A +F+ + +I DEPT G+D Y + ++ K I++ + H D+ +
Sbjct: 469 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD--R 526
Query: 235 ILLMAEGNL 243
I +++ G L
Sbjct: 527 IAIISHGKL 535
Score = 62.9 bits (146), Expect = 1e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 1375 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRPGECFGLLGVNG 1426
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 1427 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 1485
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 1486 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 1543
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 1544 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 1601
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 1602 LGSIQHLKNRF 1612
>AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subfamily
A protein.
Length = 2595
Score = 65.3 bits (152), Expect = 3e-10
Identities = 48/213 (22%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 51 VIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR-DL---- 103
V +DN + EG +++GP+GAGKTT + L G GT+ + G++++ DL
Sbjct: 1359 VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGAS-AGTIFVYGKDIKTDLHTVR 1417
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
+ Q DV LT E L+ +K+ + TK+ + +++ L +H
Sbjct: 1418 KNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVG 1477
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
+ + + +++I DEP+TG+D + + ++ K + I++ + H
Sbjct: 1478 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHL 1537
Query: 224 PSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
++ + I + +G L G+ K F
Sbjct: 1538 DEAEVLSD--RIAFLEQGGLRCCGSPFYLKEAF 1568
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 14/217 (6%)
Query: 49 KTVIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR----D 102
K + ++N I GE ++G +GAGKTT L G +P G + I + D
Sbjct: 2269 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDI-IPSSGNILIRNKTGSLGHVD 2327
Query: 103 LTGAEI--VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVET 160
+ + PQ D D +TV E L F ++ ++ K ++ ++ L +
Sbjct: 2328 SHSSLVGYCPQEDALDDLVTVEEHLYFYA--RVHGIPEKDIKETVHKLLRRLHLMPFKDR 2385
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGIL-KKLSASGKIVIC 219
A + + P IL+ DEP++G+D + + I+ +++ +++
Sbjct: 2386 ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILT 2445
Query: 220 SVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
S C+ + +M G G+ KS F
Sbjct: 2446 SHSMEECEAL--CTRLAIMVNGKFQCIGSLQHIKSRF 2480
>AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2277
Score = 65.3 bits (152), Expect = 3e-10
Identities = 48/213 (22%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 51 VIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR-DL---- 103
V +DN + EG +++GP+GAGKTT + L G GT+ + G++++ DL
Sbjct: 1041 VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGAS-AGTIFVYGKDIKTDLHTVR 1099
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
+ Q DV LT E L+ +K+ + TK+ + +++ L +H
Sbjct: 1100 KNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVG 1159
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
+ + + +++I DEP+TG+D + + ++ K + I++ + H
Sbjct: 1160 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHL 1219
Query: 224 PSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
++ + I + +G L G+ K F
Sbjct: 1220 DEAEVLSD--RIAFLEQGGLRCCGSPFYLKEAF 1250
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 14/217 (6%)
Query: 49 KTVIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR----D 102
K + ++N I GE ++G +GAGKTT L G +P G + I + D
Sbjct: 1951 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDI-IPSSGNILIRNKTGSLGHVD 2009
Query: 103 LTGAEI--VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVET 160
+ + PQ D D +TV E L F ++ ++ K ++ ++ L +
Sbjct: 2010 SHSSLVGYCPQEDALDDLVTVEEHLYFYA--RVHGIPEKDIKETVHKLLRRLHLMPFKDR 2067
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGIL-KKLSASGKIVIC 219
A + + P IL+ DEP++G+D + + I+ +++ +++
Sbjct: 2068 ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILT 2127
Query: 220 SVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
S C+ + +M G G+ KS F
Sbjct: 2128 SHSMEECEAL--CTRLAIMVNGKFQCIGSLQHIKSRF 2162
>AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2347
Score = 65.3 bits (152), Expect = 3e-10
Identities = 48/213 (22%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 51 VIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR-DL---- 103
V +DN + EG +++GP+GAGKTT + L G GT+ + G++++ DL
Sbjct: 1111 VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGAS-AGTIFVYGKDIKTDLHTVR 1169
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
+ Q DV LT E L+ +K+ + TK+ + +++ L +H
Sbjct: 1170 KNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVG 1229
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
+ + + +++I DEP+TG+D + + ++ K + I++ + H
Sbjct: 1230 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHL 1289
Query: 224 PSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
++ + I + +G L G+ K F
Sbjct: 1290 DEAEVLSD--RIAFLEQGGLRCCGSPFYLKEAF 1320
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 14/217 (6%)
Query: 49 KTVIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR----D 102
K + ++N I GE ++G +GAGKTT L G +P G + I + D
Sbjct: 2021 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDI-IPSSGNILIRNKTGSLGHVD 2079
Query: 103 LTGAEI--VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVET 160
+ + PQ D D +TV E L F ++ ++ K ++ ++ L +
Sbjct: 2080 SHSSLVGYCPQEDALDDLVTVEEHLYFYA--RVHGIPEKDIKETVHKLLRRLHLMPFKDR 2137
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGIL-KKLSASGKIVIC 219
A + + P IL+ DEP++G+D + + I+ +++ +++
Sbjct: 2138 ATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILT 2197
Query: 220 SVHQPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
S C+ + +M G G+ KS F
Sbjct: 2198 SHSMEECEAL--CTRLAIMVNGKFQCIGSLQHIKSRF 2232
>AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein.
Length = 2413
Score = 65.3 bits (152), Expect = 3e-10
Identities = 48/213 (22%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 51 VIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR-DL---- 103
V +DN + EG +++GP+GAGKTT + L G GT+ + G++++ DL
Sbjct: 1359 VAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGAS-AGTIFVYGKDIKTDLHTVR 1417
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXX 163
+ Q DV LT E L+ +K+ + TK+ + +++ L +H
Sbjct: 1418 KNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVG 1477
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
+ + + +++I DEP+TG+D + + ++ K + I++ + H
Sbjct: 1478 TLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHL 1537
Query: 224 PSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
++ + I + +G L G+ K F
Sbjct: 1538 DEAEVLSD--RIAFLEQGGLRCCGSPFYLKEAF 1568
Score = 34.3 bits (75), Expect = 0.56
Identities = 33/147 (22%), Positives = 57/147 (38%), Gaps = 11/147 (7%)
Query: 49 KTVIIDNACIR--EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVR----D 102
K + ++N I GE ++G +GAGKTT L G +P G + I + D
Sbjct: 2269 KIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGD-IIPSSGNILIRNKTGSLGHVD 2327
Query: 103 LTGAEI--VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVET 160
+ + PQ D D +TV E L F ++ ++ K ++ ++ L +
Sbjct: 2328 SHSSLVGYCPQEDALDDLVTVEEHLYFYA--RVHGIPEKDIKETVHKLLRRLHLMPFKDR 2385
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILI 187
A + + P IL+
Sbjct: 2386 ATSMCSYGTKRKLSTALALIGKPSILL 2412
>AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens
cDNA FLJ25441 fis, clone TST08455. ).
Length = 364
Score = 64.9 bits (151), Expect = 3e-10
Identities = 63/245 (25%), Positives = 100/245 (40%), Gaps = 14/245 (5%)
Query: 21 ENKDAIIVRNLKVWTPEEKS--IWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
E K +I+V NL ++K + RKV K T I + C+++GE ++GP+GAGK+T +
Sbjct: 7 EEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYI-SFCVKKGEILGLLGPNGAGKSTII 65
Query: 79 VSLAGKCTLPFEGTVTI------NGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
L G P G V + + L PQ + T+ E +K
Sbjct: 66 NILVGDIE-PTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVK 124
Query: 133 LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPT 192
G S K +++ + L H++ A S L NPQI + DEP+
Sbjct: 125 -GMSASD-MKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 182
Query: 193 TGLDSYNASQVIGILKKLSASGK-IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
TG+D + ++ + K I + H + + + +M G L GT
Sbjct: 183 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYME-EAEAVCDRVAIMVSGQLRCIGTVQH 241
Query: 252 CKSFF 256
KS F
Sbjct: 242 LKSKF 246
>AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein.
Length = 737
Score = 64.9 bits (151), Expect = 3e-10
Identities = 63/245 (25%), Positives = 100/245 (40%), Gaps = 14/245 (5%)
Query: 21 ENKDAIIVRNLKVWTPEEKS--IWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
E K +I+V NL ++K + RKV K T I + C+++GE ++GP+GAGK+T +
Sbjct: 380 EEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYI-SFCVKKGEILGLLGPNGAGKSTII 438
Query: 79 VSLAGKCTLPFEGTVTI------NGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
L G P G V + + L PQ + T+ E +K
Sbjct: 439 NILVGDIE-PTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVK 497
Query: 133 LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPT 192
G S K +++ + L H++ A S L NPQI + DEP+
Sbjct: 498 -GMSASD-MKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 555
Query: 193 TGLDSYNASQVIGILKKLSASGK-IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
TG+D + ++ + K I + H + + + +M G L GT
Sbjct: 556 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYME-EAEAVCDRVAIMVSGQLRCIGTVQH 614
Query: 252 CKSFF 256
KS F
Sbjct: 615 LKSKF 619
>AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens
cDNA FLJ31971 fis, clone NT2RP7008137, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 865
Score = 64.5 bits (150), Expect = 5e-10
Identities = 63/245 (25%), Positives = 100/245 (40%), Gaps = 14/245 (5%)
Query: 21 ENKDAIIVRNLKVWTPEEKS--IWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
E K +I+V NL ++K + RKV K T I + C+++GE ++GP+GAGK+T +
Sbjct: 508 EEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYI-SFCVKKGEILGLLGPNGAGKSTII 566
Query: 79 VSLAGKCTLPFEGTVTI------NGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
L G P G V + + L PQ + T+ E +K
Sbjct: 567 NILVGDIE-PTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVK 625
Query: 133 LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPT 192
G S K +++ + L H++ A S L NPQI + DEP+
Sbjct: 626 -GMSASD-MKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 683
Query: 193 TGLDSYNASQVIGILKKLSASGK-IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQDA 251
TG+D + ++ + K I + H + + + +M G L GT
Sbjct: 684 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYME-EAEAVCDRVAIMVSGQLRCIGTVQH 742
Query: 252 CKSFF 256
KS F
Sbjct: 743 LKSRF 747
>AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens
cDNA FLJ39977 fis, clone SPLEN2029295, moderately
similar to ATP-binding cassette, sub-family A member 8.
).
Length = 815
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 21 ENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLV 79
+ K II L K + ++KS + K K + C++EGE ++GPSGAGK++ +
Sbjct: 470 DEKPVIIASCLHKEYAGQKKSCFSKRKKKIAARNISFCVQEGEILGLLGPSGAGKSSSIR 529
Query: 80 SLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ 139
++G T P G V + G + L PQ +V LT+ E L +K K
Sbjct: 530 MISG-ITKPTAGEVELKGCS-SVLGHLGYCPQENVLWPMLTLREHLEVYAAVK--GLRKA 585
Query: 140 PNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYN 199
+ + ++ FKL + S L N +L+ DEP+TG+D
Sbjct: 586 DARLAIARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGNSPVLLLDEPSTGIDPTG 645
Query: 200 ASQV 203
Q+
Sbjct: 646 QQQM 649
>BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein.
Length = 867
Score = 62.9 bits (146), Expect = 1e-09
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 21/251 (8%)
Query: 14 QVLLDEFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSG 71
+VL + +N D + + NL T KS RK+ + + +D C +R GE ++G +G
Sbjct: 471 RVLRGDADN-DMVKIENL---TKVYKS--RKIGR--ILAVDRLCLGVRPGECFGLLGVNG 522
Query: 72 AGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAE----IVPQFDVFTDSLTVMEQLV 126
AGKT+ L G + G +NG +V ++L + PQ D D LT E L
Sbjct: 523 AGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQ 581
Query: 127 FMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQIL 186
T ++ G S K + ++ +E+ +L+ + + A + + P +
Sbjct: 582 LYTRLR-GISWKDEAR-VVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFI 639
Query: 187 ICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QPSCDIFKEFNSILLMAEGNLLF 245
DEPTTG+D + ++ L +G+ V+ + H C+ + +M G L
Sbjct: 640 FLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEAL--CTRLAIMVNGRLRC 697
Query: 246 HGTQDACKSFF 256
G+ K+ F
Sbjct: 698 LGSIQHLKNRF 708
>BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein.
Length = 419
Score = 62.1 bits (144), Expect = 2e-09
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 32 KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEG 91
K + +KS + + K + + C+++GE ++G +GAGK+T + + G CT P G
Sbjct: 79 KEYYETKKSCFSTIKKKIAIRNVSFCVKKGEVLGLLGHNGAGKSTSIKMITG-CTKPTAG 137
Query: 92 TVTING--RNVR-----DLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK-LGNSTKQPNKS 143
V + G +VR L PQ + LT+ E L +K LG K+
Sbjct: 138 VVVLQGSRASVRQQHDNSLKFLGYCPQENSLWPKLTMKEHLELYAAVKGLG---KEDAAL 194
Query: 144 ILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV 203
++ ++E KL ++ S L NP +++ DEP TG+D Q+
Sbjct: 195 SISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQM 254
Query: 204 IGILK 208
IL+
Sbjct: 255 WQILQ 259
>AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein
protein.
Length = 373
Score = 62.1 bits (144), Expect = 2e-09
Identities = 52/216 (24%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 49 KTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTG 105
+ + +D C +R GE ++G +GAGKT+ L G + G +NG +V ++L
Sbjct: 4 RILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQ 62
Query: 106 AE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETX 161
+ PQ D D LT E L T ++ G S K + ++ +E+ +L+ + +
Sbjct: 63 VQQSLGYCPQCDALFDELTAREHLQLYTRLR-GISWKDEAR-VVKWALEKLELTKYADKP 120
Query: 162 XXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSV 221
A + + P + DEPTTG+D + ++ L +G+ V+ +
Sbjct: 121 AGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTS 180
Query: 222 H-QPSCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
H C+ + +M G L G+ K+ F
Sbjct: 181 HSMEECEAL--CTRLAIMVNGRLRCLGSIQHLKNRF 214
>AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 226
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/181 (24%), Positives = 81/181 (44%), Gaps = 10/181 (5%)
Query: 49 KTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTG 105
+ + +D C +R GE ++G +GAGKT+ L G + G +NG +V ++L
Sbjct: 20 RILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTT-GGEAFVNGHSVLKELLQ 78
Query: 106 AE----IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETX 161
+ PQ D D LT E L T ++ G S K + ++ +E+ +L+ + +
Sbjct: 79 VQQSLGYCPQCDALFDELTAREHLQLYTRLR-GISWKDEAR-VVKWALEKLELTKYADKP 136
Query: 162 XXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSV 221
A + + P + DEPTTG+D + ++ L +G+ V+ +
Sbjct: 137 AGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTS 196
Query: 222 H 222
H
Sbjct: 197 H 197
>AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.
Length = 1591
Score = 60.9 bits (141), Expect = 6e-09
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 5/186 (2%)
Query: 20 FENKDAIIVRNL-KVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
F+ K II L K + + K + K + C+R+GE ++G +GAGK+T +
Sbjct: 1244 FDEKPVIIASCLRKEYAGKRKGCFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSI 1303
Query: 79 VSLAGKCTLPFEGTVTINGRNVRD-LTGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNST 137
+ G T P G V + G D L PQ + +LTV + L +K
Sbjct: 1304 KVITGD-TKPTAGQVLLKGSGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVK--GLR 1360
Query: 138 KQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDS 197
K + + +++ KL +++ S L NP +++ DEP+TG+D
Sbjct: 1361 KGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1420
Query: 198 YNASQV 203
Q+
Sbjct: 1421 EGQQQM 1426
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/121 (36%), Positives = 66/121 (54%), Gaps = 14/121 (11%)
Query: 19 EFENKDAIIVRNLKVWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFL 78
EF+ K+AI +RN+ T E K K+ K ++ D I EG+ AI+G SGAGK+T L
Sbjct: 483 EFQGKEAIRIRNV---TKEYKGKPDKIEALKDLVFD---IYEGQITAILGHSGAGKSTLL 536
Query: 79 VSLAGKCTLPFEGTVTINGRNVRDLTGAE-------IVPQFDVFTDSLTVMEQLVFMTEM 131
L+G ++P +G+VTI + ++ E + PQ +V D LTV E L ++
Sbjct: 537 NILSG-LSVPTKGSVTIYNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKI 595
Query: 132 K 132
K
Sbjct: 596 K 596
Score = 33.9 bits (74), Expect = 0.74
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 184 QILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNL 243
+I + DEPT GLD ++ QV +LK+ I+ + DI + + +++G L
Sbjct: 606 EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRK--VFLSQGKL 663
Query: 244 LFHGTQDACKSFFESIDLHCPLNYN 268
G+ K + I H L N
Sbjct: 664 KCAGSSLFLKKKW-GIGYHLSLQLN 687
>AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member 7
protein.
Length = 2146
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
+G A +G +GAGKTT L L+G P G+ I G +VR A + PQ++V
Sbjct: 833 QGHITAFLGHNGAGKTTTLSILSGLFP-PSGGSAFILGHDVRSSMAAIRPHLGVCPQYNV 891
Query: 115 FTDSLTVMEQLVFMTEMK-LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXX 173
D LTV E + F +K L + P + L +++ L +
Sbjct: 892 LFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRL---LQDVGLVSKQSVQTRHLSGGMQRKL 948
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH 222
A +F+ Q++I DEPT G+D + + +L K G+ +I S H
Sbjct: 949 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY-REGRTLILSTH 996
Score = 47.2 bits (107), Expect = 7e-05
Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Query: 53 IDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAEI- 108
+D C I GE ++G +GAGKT+ + G TL G + G +V R+ + A +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGD-TLASRGEAVLAGHSVAREPSAAHLS 1868
Query: 109 ---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
PQ D + LT E L + ++ G Q ++ + + LS + +
Sbjct: 1869 MGYCPQSDAIFELLTGREHLELLARLR-GVPEAQVAQTA-GSGLARLGLSWYADRPAGTY 1926
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QP 224
A + + +P ++ DEPTTG+D + L + G+ V+ + H
Sbjct: 1927 SGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHSME 1986
Query: 225 SCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + + +M G G+ K F
Sbjct: 1987 ECEAL--CSRLAIMVNGRFRCLGSPQHLKGRF 2016
>AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7
protein.
Length = 2146
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
+G A +G +GAGKTT L L+G P G+ I G +VR A + PQ++V
Sbjct: 833 QGHITAFLGHNGAGKTTTLSILSGLFP-PSGGSAFILGHDVRSSMAAIRPHLGVCPQYNV 891
Query: 115 FTDSLTVMEQLVFMTEMK-LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXX 173
D LTV E + F +K L + P + L +++ L +
Sbjct: 892 LFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRL---LQDVGLVSKQSVQTRHLSGGMQRKL 948
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH 222
A +F+ Q++I DEPT G+D + + +L K G+ +I S H
Sbjct: 949 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY-REGRTLILSTH 996
Score = 47.2 bits (107), Expect = 7e-05
Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Query: 53 IDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAEI- 108
+D C I GE ++G +GAGKT+ + G TL G + G +V R+ + A +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGD-TLASRGEAVLAGHSVAREPSAAHLS 1868
Query: 109 ---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
PQ D + LT E L + ++ G Q ++ + + LS + +
Sbjct: 1869 MGYCPQSDAIFELLTGREHLELLARLR-GVPEAQVAQTA-GSGLARLGLSWYADRPAGTY 1926
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QP 224
A + + +P ++ DEPTTG+D + L + G+ V+ + H
Sbjct: 1927 SGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHSME 1986
Query: 225 SCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + + +M G G+ K F
Sbjct: 1987 ECEAL--CSRLAIMVNGRFRCLGSPQHLKGRF 2016
>AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transporter
protein.
Length = 2146
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
+G A +G +GAGKTT L L+G P G+ I G +VR A + PQ++V
Sbjct: 833 QGHITAFLGHNGAGKTTTLSILSGLFP-PSGGSAFILGHDVRSSMAAIRPHLGVCPQYNV 891
Query: 115 FTDSLTVMEQLVFMTEMK-LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXX 173
D LTV E + F +K L + P + L +++ L +
Sbjct: 892 LFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRL---LQDVGLVSKQSVQTRHLSGGMQRKL 948
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH 222
A +F+ Q++I DEPT G+D + + +L K G+ +I S H
Sbjct: 949 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY-REGRTLILSTH 996
Score = 47.2 bits (107), Expect = 7e-05
Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Query: 53 IDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAEI- 108
+D C I GE ++G +GAGKT+ + G TL G + G +V R+ + A +
Sbjct: 1810 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGD-TLASRGEAVLAGHSVAREPSAAHLS 1868
Query: 109 ---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
PQ D + LT E L + ++ G Q ++ + + LS + +
Sbjct: 1869 MGYCPQSDAIFELLTGREHLELLARLR-GVPEAQVAQTA-GSGLARLGLSWYADRPAGTY 1926
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QP 224
A + + +P ++ DEPTTG+D + L + G+ V+ + H
Sbjct: 1927 SGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHSME 1986
Query: 225 SCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + + +M G G+ K F
Sbjct: 1987 ECEAL--CSRLAIMVNGRFRCLGSPQHLKGRF 2016
>AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein.
Length = 2008
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 60 EGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGA-----EIVPQFDV 114
+G A +G +GAGKTT L L+G P G+ I G +VR A + PQ++V
Sbjct: 695 QGHITAFLGHNGAGKTTTLSILSGLFP-PSGGSAFILGHDVRSSMAAIRPHLGVCPQYNV 753
Query: 115 FTDSLTVMEQLVFMTEMK-LGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXXXXX 173
D LTV E + F +K L + P + L +++ L +
Sbjct: 754 LFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRL---LQDVGLVSKQSVQTRHLSGGMQRKL 810
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH 222
A +F+ Q++I DEPT G+D + + +L K G+ +I S H
Sbjct: 811 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY-REGRTLILSTH 858
Score = 47.2 bits (107), Expect = 7e-05
Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Query: 53 IDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAEI- 108
+D C I GE ++G +GAGKT+ + G TL G + G +V R+ + A +
Sbjct: 1672 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGD-TLASRGEAVLAGHSVAREPSAAHLS 1730
Query: 109 ---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
PQ D + LT E L + ++ G Q ++ + + LS + +
Sbjct: 1731 MGYCPQSDAIFELLTGREHLELLARLR-GVPEAQVAQTA-GSGLARLGLSWYADRPAGTY 1788
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVH-QP 224
A + + +P ++ DEPTTG+D + L + G+ V+ + H
Sbjct: 1789 SGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHSME 1848
Query: 225 SCDIFKEFNSILLMAEGNLLFHGTQDACKSFF 256
C+ + + +M G G+ K F
Sbjct: 1849 ECEAL--CSRLAIMVNGRFRCLGSPQHLKGRF 1878
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 14/215 (6%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P+ I++ N I+ GE A++GPSGAGK+T L L + P EG VT++G ++R L
Sbjct: 431 SRPEVKILNDLNMAIKPGEMTALVGPSGAGKSTAL-QLIQRFYDPCEGMVTVDGHDIRSL 489
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTVIE-EFKLS 155
+ Q + S T+ E + + E Q K + N +++ +
Sbjct: 490 NIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFD 549
Query: 156 AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGK 215
V A + + NP+IL+ D T+ LD+ + + V +L K+ G
Sbjct: 550 TLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQ-HGH 608
Query: 216 IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
+I H+ S + ++I+ G + GT +
Sbjct: 609 TIISVAHRLS--TVRAADTIIGFEHGTAVERGTHE 641
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/218 (22%), Positives = 99/218 (45%), Gaps = 18/218 (8%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P + +++ + I G+ A +G SG GK+T + L + P +G V I+G + + +
Sbjct: 1089 SRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTS-IQLLERFYDPDQGKVMIDGHDSKKV 1147
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ-PNKSILNTV----IEEFKLS--- 155
+ + + V+ M +K G++TK+ P + ++ + +F +S
Sbjct: 1148 NVQFLRSNIGIVSQE-PVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPE 1206
Query: 156 ---AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+V + A + + +P+IL+ DE T+ LD+ + V L K +
Sbjct: 1207 KYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDK-AR 1265
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ I H+ S + + I +MA+G ++ GT +
Sbjct: 1266 EGRTCIVIAHRLS--TIQNADIIAVMAQGVVIEKGTHE 1301
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 14/215 (6%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P+ I++ N I+ GE A++GPSGAGK+T L L + P EG VT++G ++R L
Sbjct: 431 SRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTAL-QLIQRFYDPCEGMVTVDGHDIRSL 489
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTVIE-EFKLS 155
+ Q + S T+ E + + E Q K + N +++ +
Sbjct: 490 NIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFD 549
Query: 156 AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGK 215
V A + + NP+IL+ D T+ LD+ + + V +L K+ G
Sbjct: 550 TLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQ-HGH 608
Query: 216 IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
+I H+ S + ++I+ G + GT +
Sbjct: 609 TIISVAHRLS--TVRAADTIIGFEHGTAVERGTHE 641
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/218 (22%), Positives = 99/218 (45%), Gaps = 18/218 (8%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P + +++ + I G+ A +G SG GK+T + L + P +G V I+G + + +
Sbjct: 1089 SRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTS-IQLLERFYDPDQGKVMIDGHDSKKV 1147
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ-PNKSILNTV----IEEFKLS--- 155
+ + + V+ M +K G++TK+ P + ++ + +F +S
Sbjct: 1148 NVQFLRSNIGIVSQE-PVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPE 1206
Query: 156 ---AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+V + A + + +P+IL+ DE T+ LD+ + V L K +
Sbjct: 1207 KYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDK-AR 1265
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ I H+ S + + I +MA+G ++ GT +
Sbjct: 1266 EGRTCIVIAHRLS--TIQNADIIAVMAQGVVIEKGTHE 1301
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 14/215 (6%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P+ I++ N I+ GE A++GPSGAGK+T L L + P EG VT++G ++R L
Sbjct: 431 SRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTAL-QLIQRFYDPCEGMVTVDGHDIRSL 489
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTVIE-EFKLS 155
+ Q + S T+ E + + E Q K + N +++ +
Sbjct: 490 NIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFD 549
Query: 156 AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGK 215
V A + + NP+IL+ D T+ LD+ + + V +L K+ G
Sbjct: 550 TLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQ-HGH 608
Query: 216 IVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
+I H+ S + ++I+ G + GT +
Sbjct: 609 TIISVAHRLS--TVRAADTIIGFEHGTAVERGTHE 641
>AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein.
Length = 738
Score = 55.2 bits (127), Expect = 3e-07
Identities = 52/218 (23%), Positives = 96/218 (44%), Gaps = 17/218 (7%)
Query: 46 AKPKTVIIDN--ACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
A+P+ I + I G A++GPSG+GK+T L SL + P GT++++G ++R L
Sbjct: 503 ARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVL-SLLLRLYNPASGTISLDGHDIRQL 561
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTV--IEEFK- 153
+ + + S ++ E + + + + ++ + + N V I F
Sbjct: 562 NPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQ 621
Query: 154 -LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+ V A + L NP+IL+ DE T+ LD+ N V L +L
Sbjct: 622 GFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-M 680
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ V+ H+ S K N + ++ +G + +G +
Sbjct: 681 DGRTVLVIAHRLS--TIKNANMVAVLDQGKITEYGKHE 716
>BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 54.8 bits (126), Expect = 4e-07
Identities = 52/218 (23%), Positives = 96/218 (44%), Gaps = 17/218 (7%)
Query: 46 AKPKTVIIDN--ACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
A+P+ I + I G A++GPSG+GK+T L SL + P GT++++G ++R L
Sbjct: 503 ARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVL-SLLLRLYDPASGTISLDGHDIRQL 561
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTV--IEEFK- 153
+ + + S ++ E + + + + ++ + + N V I F
Sbjct: 562 NPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQ 621
Query: 154 -LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+ V A + L NP+IL+ DE T+ LD+ N V L +L
Sbjct: 622 GFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-M 680
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ V+ H+ S K N + ++ +G + +G +
Sbjct: 681 DGRTVLVIAHRLS--TIKNANMVAVLDQGKITEYGKHE 716
>AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 54.8 bits (126), Expect = 4e-07
Identities = 52/218 (23%), Positives = 96/218 (44%), Gaps = 17/218 (7%)
Query: 46 AKPKTVIIDN--ACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
A+P+ I + I G A++GPSG+GK+T L SL + P GT++++G ++R L
Sbjct: 503 ARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVL-SLLLRLYDPASGTISLDGHDIRQL 561
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTV--IEEFK- 153
+ + + S ++ E + + + + ++ + + N V I F
Sbjct: 562 NPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQ 621
Query: 154 -LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+ V A + L NP+IL+ DE T+ LD+ N V L +L
Sbjct: 622 GFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-M 680
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ V+ H+ S K N + ++ +G + +G +
Sbjct: 681 DGRTVLVIAHRLS--TIKNANMVAVLDQGKITEYGKHE 716
>AK172794-1|BAD18770.1| 433|Homo sapiens protein ( Homo sapiens
cDNA FLJ23955 fis, clone HEP11276, highly similar to
Homo sapiens ATP-binding cassette, sub-family B
(MDR/TAP), member ).
Length = 433
Score = 54.8 bits (126), Expect = 4e-07
Identities = 52/218 (23%), Positives = 96/218 (44%), Gaps = 17/218 (7%)
Query: 46 AKPKTVIIDN--ACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
A+P+ I + I G A++GPSG+GK+T L SL + P GT++++G ++R L
Sbjct: 198 ARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVL-SLLLRLYDPASGTISLDGHDIRQL 256
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNK--SILNTV--IEEFK- 153
+ + + S ++ E + + + + ++ + + N V I F
Sbjct: 257 NPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQ 316
Query: 154 -LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+ V A + L NP+IL+ DE T+ LD+ N V L +L
Sbjct: 317 GFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-M 375
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ V+ H+ S K N + ++ +G + +G +
Sbjct: 376 DGRTVLVIAHRLS--TIKNANMVAVLDQGKITEYGKHE 411
>AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding cassette
protein protein.
Length = 737
Score = 54.4 bits (125), Expect = 5e-07
Identities = 48/217 (22%), Positives = 94/217 (43%), Gaps = 16/217 (7%)
Query: 46 AKPKTVIIDN--ACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
A+P+ I + I G A++GPSG+GK+T L SL + P GT++++G ++R L
Sbjct: 503 ARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVL-SLLLRLYDPASGTISLDGHDIRQL 561
Query: 104 TGAEIVPQFDVFTD-----SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFK----- 153
+ + + S ++ E + + + + ++ + + + +
Sbjct: 562 NPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRGLKGQAVAFIRNFPQG 621
Query: 154 LSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSAS 213
+ V A + L NP+IL+ DE T+ LD+ N V L +L
Sbjct: 622 FNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-MD 680
Query: 214 GKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ V+ H+ S K N + ++ +G + +G +
Sbjct: 681 GRTVLVIAHRLS--TIKNANMVAVLDQGKITEYGKHE 715
>AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding
transporter 1 protein.
Length = 849
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Query: 88 PFEGTVTINGRNVRDLTGA-----EIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNK 142
P GT I G+++R + PQ +V D LTV E + F +K G S K
Sbjct: 9 PTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLK-GLSEKHVKA 67
Query: 143 SILNTVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQ 202
+ ++ S+ +++ A +F+ +++I DEPT G+D Y+
Sbjct: 68 EMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRG 127
Query: 203 VIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
+ +L K I++ + H D+ + I +++ G L G+
Sbjct: 128 IWELLLKYRQGRTIILSTHHMDEADVLGD--RIAIISHGKLCCVGS 171
>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
glycoprotein P (mdr3) mRNA, complete cds. ).
Length = 1279
Score = 52.0 bits (119), Expect = 3e-06
Identities = 47/201 (23%), Positives = 90/201 (44%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EGT+ I+G+++R+ + V
Sbjct: 416 NLKVQSGQTVALVGSSGCGKST-TVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ S T+ E + + +T ++ + K+ N + + K V
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQ-KFDTLVGERGAQL 533
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + ++V L K + G+ I H+ S
Sbjct: 534 SGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK-AREGRTTIVIAHRLS 592
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F +++ +G+
Sbjct: 593 TVRNADVIAGFEDGVIVEQGS 613
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/201 (21%), Positives = 85/201 (42%), Gaps = 14/201 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+++G+ A++G SG GK+T +V L + P GTV ++G+ + L + Q + +
Sbjct: 1059 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQ 1117
Query: 118 S-----LTVMEQLVFMTEMKLGNSTK---QPNKSILNTVIEEF--KLSAHVETXXXXXXX 167
++ E + + ++ + + + ++ IE K V
Sbjct: 1118 EPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSG 1177
Query: 168 XXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCD 227
A + + PQIL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1178 GQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS-- 1234
Query: 228 IFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1235 TIQNADLIVVFQNGRVKEHGT 1255
>EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 52.0 bits (119), Expect = 3e-06
Identities = 47/201 (23%), Positives = 90/201 (44%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EGT+ I+G+++R+ + V
Sbjct: 416 NLKVQSGQTVALVGSSGCGKST-TVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ S T+ E + + +T ++ + K+ N + + K V
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQ-KFDTLVGERGAQL 533
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + ++V L K + G+ I H+ S
Sbjct: 534 SGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK-AREGRTTIVIAHRLS 592
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F +++ +G+
Sbjct: 593 TVRNADVIAGFEDGVIVEQGS 613
Score = 36.3 bits (80), Expect = 0.14
Identities = 44/208 (21%), Positives = 85/208 (40%), Gaps = 21/208 (10%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN-------GRNVRDLTGAEIVP 110
+++G+ A++G SG GK+T +V L + P GTV ++ G+ + L +
Sbjct: 1059 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRA 1117
Query: 111 QFDVFTDS-----LTVMEQLVFMTEMKLGNSTK---QPNKSILNTVIEEF--KLSAHVET 160
Q + + ++ E + + ++ + + + ++ IE K V
Sbjct: 1118 QLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGD 1177
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICS 220
A + + PQIL+ DE T+ LD+ + V L K + G+ I
Sbjct: 1178 KGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK-AREGRTCIVI 1236
Query: 221 VHQPSCDIFKEFNSILLMAEGNLLFHGT 248
H+ S + + I++ G + HGT
Sbjct: 1237 AHRLS--TIQNADLIVVFQNGRVKEHGT 1262
>BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 52.0 bits (119), Expect = 3e-06
Identities = 47/201 (23%), Positives = 90/201 (44%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EGT+ I+G+++R+ + V
Sbjct: 416 NLKVQSGQTVALVGSSGCGKST-TVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGV 474
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ S T+ E + + +T ++ + K+ N + + K V
Sbjct: 475 VSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQ-KFDTLVGERGAQL 533
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + ++V L K + G+ I H+ S
Sbjct: 534 SGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK-AREGRTTIVIAHRLS 592
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F +++ +G+
Sbjct: 593 TVRNADVIAGFEDGVIVEQGS 613
Score = 36.3 bits (80), Expect = 0.14
Identities = 44/208 (21%), Positives = 85/208 (40%), Gaps = 21/208 (10%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN-------GRNVRDLTGAEIVP 110
+++G+ A++G SG GK+T +V L + P GTV ++ G+ + L +
Sbjct: 1059 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRA 1117
Query: 111 QFDVFTDS-----LTVMEQLVFMTEMKLGNSTK---QPNKSILNTVIEEF--KLSAHVET 160
Q + + ++ E + + ++ + + + ++ IE K V
Sbjct: 1118 QLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGD 1177
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICS 220
A + + PQIL+ DE T+ LD+ + V L K + G+ I
Sbjct: 1178 KGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK-AREGRTCIVI 1236
Query: 221 VHQPSCDIFKEFNSILLMAEGNLLFHGT 248
H+ S + + I++ G + HGT
Sbjct: 1237 AHRLS--TIQNADLIVVFQNGRVKEHGT 1262
>BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/200 (25%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 483 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 541
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 542 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 600
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFK 230
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+ S +
Sbjct: 601 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLVIAHRLS--TVR 657
Query: 231 EFNSILLMAEGNLLFHGTQD 250
+ I++MA+G + GT +
Sbjct: 658 GAHCIVVMADGRVWEAGTHE 677
>AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette,
sub-family B, member 8 variant protein.
Length = 718
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/200 (25%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 483 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 541
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 542 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 600
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFK 230
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+ S +
Sbjct: 601 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLVIAHRLS--TVR 657
Query: 231 EFNSILLMAEGNLLFHGTQD 250
+ I++MA+G + GT +
Sbjct: 658 GAHCIVVMADGRVWEAGTHE 677
>AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens
cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to
Homo sapiens ATP-binding cassette protein M-ABC1 mRNA.
).
Length = 701
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/200 (25%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 466 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 524
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 525 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 583
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFK 230
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+ S +
Sbjct: 584 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLVIAHRLS--TVR 640
Query: 231 EFNSILLMAEGNLLFHGTQD 250
+ I++MA+G + GT +
Sbjct: 641 GAHCIVVMADGRVWEAGTHE 660
>AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens
cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to
ATP-DEPENDENT PERMEASE MDL1. ).
Length = 735
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/200 (25%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 500 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 558
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 559 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 617
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFK 230
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+ S +
Sbjct: 618 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLVIAHRLS--TVR 674
Query: 231 EFNSILLMAEGNLLFHGTQD 250
+ I++MA+G + GT +
Sbjct: 675 GAHCIVVMADGRVWEAGTHE 694
>AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette
protein M-ABC1 protein.
Length = 718
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/200 (25%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 483 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 541
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 542 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 600
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFK 230
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+ S +
Sbjct: 601 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLVIAHRLS--TVR 657
Query: 231 EFNSILLMAEGNLLFHGTQD 250
+ I++MA+G + GT +
Sbjct: 658 GAHCIVVMADGRVWEAGTHE 677
>AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ46673 fis, clone TRACH3009061, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 788
Score = 47.6 bits (108), Expect = 6e-05
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 15/209 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTV--TINGRNVRDLTGAEIV------ 109
I +GE ++G +GAGK+T L G+ +L + T G V DL+ A
Sbjct: 474 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAV-DLSSAGTAGVLIGY 532
Query: 110 -PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXX 168
PQ D + LT E L + ++ +Q + +I L AH +
Sbjct: 533 CPQQDALDELLTGWEHLYYYCSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGG 590
Query: 169 XXXXXXXATSFLSNPQILICDEPTTGLDSYNASQV-IGILKKLSASGKIVICSVHQPSCD 227
A + + P IL+ DEP++G+D + + I+K++ V+ S C+
Sbjct: 591 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECE 650
Query: 228 IFKEFNSILLMAEGNLLFHGTQDACKSFF 256
+ +M G+ G+ K+ F
Sbjct: 651 AL--CTRLAIMVNGSFKCLGSPQHIKNRF 677
>U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette protein
protein.
Length = 229
Score = 47.2 bits (107), Expect = 7e-05
Identities = 51/207 (24%), Positives = 90/207 (43%), Gaps = 21/207 (10%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRN---------VRDLTGAEI 108
I G A++GPSG+GK+T L SL + P GT++++G + +R G
Sbjct: 8 IPSGSVTALVGPSGSGKSTVL-SLLLRLYDPASGTISLDGHDNPSAKPSVWLRSKIGT-- 64
Query: 109 VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNK--SILNTVIE-EF--KLSAHVETXXX 163
V Q + S ++ E + + + + ++ + + N V EF + + V
Sbjct: 65 VSQEPILF-SCSIAENIAYGADDPSSVTAEEIQRVAEVANAVASPEFPPRFNTVVGEKGV 123
Query: 164 XXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
A + L NP+IL+ DE T+ LD+ N V L +L G+ V+ H
Sbjct: 124 LLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRL-MDGRTVLVIAH- 181
Query: 224 PSCDIFKEFNSILLMAEGNLLFHGTQD 250
S K N + ++ +G + +G +
Sbjct: 182 -SLSTIKNANMVAVLDQGKITEYGKHE 207
>AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein
protein.
Length = 269
Score = 47.2 bits (107), Expect = 7e-05
Identities = 43/178 (24%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 53 IDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNV-RDLTGAEI- 108
+D C I GE ++G +GAGKT+ + G TL G + G +V R+ + A +
Sbjct: 91 VDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGD-TLASRGEAVLAGHSVAREPSAAHLS 149
Query: 109 ---VPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
PQ D + LT E L + ++ G Q ++ + + LS + +
Sbjct: 150 MGYCPQSDAIFELLTGREHLELLARLR-GVPEAQVAQTA-GSGLARLGLSWYADRPAGTY 207
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
A + + +P ++ DEPTTG+D + L + G+ V+ + H+
Sbjct: 208 SGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHR 265
>AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant
protein.
Length = 776
Score = 47.2 bits (107), Expect = 7e-05
Identities = 54/239 (22%), Positives = 102/239 (42%), Gaps = 17/239 (7%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 307 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 366
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
GK++ L ++ G+ P G V+++GR A + Q VF S T+ ++F E +
Sbjct: 367 GKSSLLSAVLGELA-PSHGLVSVHGRI------AYVSQQPWVF--SGTLRSNILFGKEYE 417
Query: 133 LGNSTKQPNKSILN---TVIEEFKLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICD 189
K L ++E+ L+ + A + + I + D
Sbjct: 418 KERYEKVIKACALKKDLQLLEDGDLTV-IGDRGTTLSGGQKARVNLARAVYQDADIYLLD 476
Query: 190 EPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGT 248
+P + +D+ + + + KI I HQ K + IL++ +G ++ GT
Sbjct: 477 DPLSAVDAEVSRHLFELCICQILHEKITILVTHQ--LQYLKAASQILILKDGKMVQKGT 533
>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
Length = 1280
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 414 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 472
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 473 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 531
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 532 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 590
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 591 TVRNADVIAGFDDGVIVEKGN 611
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 1060 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 1118
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 1119 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 1177
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1178 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1235
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1236 -TIQNADLIVVFQNGRVKEHGT 1256
>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
Length = 1280
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 414 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 472
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 473 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 531
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 532 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 590
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 591 TVRNADVIAGFDDGVIVEKGN 611
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 1060 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 1118
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 1119 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 1177
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1178 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1235
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1236 -TIQNADLIVVFQNGRVKEHGT 1256
>BC141836-1|AAI41837.1| 693|Homo sapiens Unknown (protein for
MGC:165100) protein.
Length = 693
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 13/173 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD--- 117
G+ A++G SG GKTT + SL + P G V ++GR++R L + + Q F
Sbjct: 483 GKIVALVGQSGGGKTT-VASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEP 541
Query: 118 ---SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXXX 170
T+ME + F ++ ++ + ++ N T E + V
Sbjct: 542 VLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPE-GYNTVVGERGTTLSGGQK 600
Query: 171 XXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQ 223
A + + P +LI DE T+ LD+ + V L + SA G+ V+ H+
Sbjct: 601 QRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA-GRTVLAGTHE 652
>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 414 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 472
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 473 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 531
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 532 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 590
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 591 TVRNADVIAGFDDGVIVEKGN 611
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 1060 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 1118
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 1119 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 1177
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1178 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1235
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1236 -TIQNADLIVVFQNGRVKEHGT 1256
>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 414 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 472
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 473 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 531
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 532 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 590
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 591 TVRNADVIAGFDDGVIVEKGN 611
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 1060 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 1118
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 1119 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 1177
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1178 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1235
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1236 -TIQNADLIVVFQNGRVKEHGT 1256
>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
Length = 1279
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 413 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 471
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 472 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 530
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 531 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 589
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 590 TVRNADVIAGFDDGVIVEKGN 610
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 1059 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 1117
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 1118 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 1176
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 1177 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1234
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1235 -TIQNADLIVVFQNGRVKEHGT 1255
>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance
protein 1 variant protein.
Length = 1062
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 16/201 (7%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N ++ G+ A++G SG GK+T V L + P EG V+++G+++R + + V
Sbjct: 196 NLKVQSGQTVALVGNSGCGKST-TVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGV 254
Query: 115 FTD-----SLTVMEQLVF----MTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXX 165
+ + T+ E + + +T ++ + K+ N + K V
Sbjct: 255 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPH-KFDTLVGERGAQL 313
Query: 166 XXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPS 225
A + + NP+IL+ DE T+ LD+ + V+ + + G+ I H+ S
Sbjct: 314 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQVALDKARKGRTTIVIAHRLS 372
Query: 226 ----CDIFKEFNSILLMAEGN 242
D+ F+ +++ +GN
Sbjct: 373 TVRNADVIAGFDDGVIVEKGN 393
Score = 45.2 bits (102), Expect = 3e-04
Identities = 46/202 (22%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
+++G+ A++G SG GK+T +V L + P G V ++G+ ++ L IV Q
Sbjct: 842 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQ 900
Query: 112 FDVFTDSLTVMEQLVFMTEMKLGNS---TKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
+ D ++ E + + ++ + + ++ ++ IE K S V
Sbjct: 901 EPILFD-CSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLS 959
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + + P IL+ DE T+ LD+ + V L K + G+ I H+ S
Sbjct: 960 GGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK-AREGRTCIVIAHRLS- 1017
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I++ G + HGT
Sbjct: 1018 -TIQNADLIVVFQNGRVKEHGT 1038
>BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein.
Length = 859
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette
transporter C4 protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug
resistance-associated protein protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette
protein C4 splice variant A protein.
Length = 1278
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B
protein.
Length = 1325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 15 VLLDEFENKDAIIVRNLK--VWTPEEKSIWRKVAKPKTVIIDNACIREGEFAAIIGPSGA 72
+LLDE ++ + + K V + + W K ++ T+ + +R GE A++GP GA
Sbjct: 390 LLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGA 449
Query: 73 GKTTFLVSLAGKCTLPFEGTVTINGR 98
GK++ L ++ G+ P G V+++GR
Sbjct: 450 GKSSLLSAVLGELA-PSHGLVSVHGR 474
>AC069137-4|AAY24100.1| 451|Homo sapiens unknown protein.
Length = 451
Score = 45.6 bits (103), Expect = 2e-04
Identities = 48/218 (22%), Positives = 99/218 (45%), Gaps = 18/218 (8%)
Query: 46 AKPKTVIID--NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL 103
++P + +++ + I G+ A +G SG GK+T + L + P +G V I+G + + +
Sbjct: 219 SRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTS-IQLLERFYDPDQGKVMIDGHDSKKV 277
Query: 104 TGAEIVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQ-PNKSILNTV----IEEFKLS--- 155
+ + + V+ M +K G++TK+ P + ++ + +F +S
Sbjct: 278 NVQFLRSNIGIVSQE-PVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPE 336
Query: 156 ---AHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSA 212
+V + A + + +P+IL+ DE T+ LD+ + V L K +
Sbjct: 337 KYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDK-AR 395
Query: 213 SGKIVICSVHQPSCDIFKEFNSILLMAEGNLLFHGTQD 250
G+ I H+ S + + I +MA+G ++ GT +
Sbjct: 396 EGRTCIVIAHRLS--TIQNADIIAVMAQGVVIEKGTHE 431
>U83661-1|AAB71758.2| 1437|Homo sapiens multidrug resistance protein
5 protein.
Length = 1437
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 585 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 635
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 636 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 695
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 696 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 753
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 754 IFMKEGCITERGTHE 768
>BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 595 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 653
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 654 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 712
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 713 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 771
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 772 --IQNADLIVVLHNGKIKEQGT 791
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 91 ARALVRNPKILILDEATSALDSESKSAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 147
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 148 VTLKDGMLAEKG 159
>BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 595 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 653
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 654 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 712
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 713 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 771
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 772 --IQNADLIVVLHNGKIKEQGT 791
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 91 ARALVRNPKILILDEATSALDSESKSAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 147
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 148 VTLKDGMLAEKG 159
>BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein.
Length = 301
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 72 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 130
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 131 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 187
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 188 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 246
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 247 VV--NADQILVIKDGCIVERGRHEALLS 272
>BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 6 protein.
Length = 842
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 613 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 671
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 672 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 728
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 729 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 787
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 788 VV--NADQILVIKDGCIVERGRHEALLS 813
>AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5
protein.
Length = 812
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 595 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 653
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 654 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 712
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 713 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 771
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 772 --IQNADLIVVLHNGKIKEQGT 791
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 91 ARALVRNPKILILDEATSALDSESKSAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 147
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 148 VTLKDGMLAEKG 159
>AY196484-1|AAO49801.1| 1394|Homo sapiens ATP-binding cassette C5
splicing variant A protein.
Length = 1394
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 585 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 635
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 636 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 695
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 696 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 753
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 754 IFMKEGCITERGTHE 768
>AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein.
Length = 812
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 595 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 653
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 654 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 712
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 713 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 771
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 772 --IQNADLIVVLHNGKIKEQGT 791
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 91 ARALVRNPKILILDEATSALDSESKSAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 147
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 148 VTLKDGMLAEKG 159
>AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ32464 fis, clone SKNMC1000251, highly similar to
Homo sapiens MT-ABC transporter (MTABC) mRNA. ).
Length = 766
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 537 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 595
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 596 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 652
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 653 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 711
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 712 VV--NADQILVIKDGCIVERGRHEALLS 737
>AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat
protein.
Length = 842
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 613 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 671
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 672 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 728
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 729 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 787
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 788 VV--NADQILVIKDGCIVERGRHEALLS 813
>AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein.
Length = 832
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 615 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 673
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 674 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 732
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 733 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 791
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 792 --IQNADLIVVLHNGKIKEQGT 811
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 111 ARALVRNPKILILDEATSALDSESKSAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 167
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 168 VTLKDGMLAEKG 179
>AF319622-1|AAN76500.1| 681|Homo sapiens P-glycoprotein protein.
Length = 681
Score = 43.6 bits (98), Expect = 0.001
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 464 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 522
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 523 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLS 581
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 582 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 640
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 641 --IQNADLIVVLHNGKIKEQGT 660
>AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette
half-transporter protein.
Length = 896
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 667 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 725
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 726 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 782
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 783 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 841
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 842 VV--NADQILVIKDGCIVERGRHEALLS 867
>AF146074-1|AAD37716.1| 1437|Homo sapiens ABC protein protein.
Length = 1437
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 585 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 635
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 636 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 695
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 696 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 753
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 754 IFMKEGCITERGTHE 768
>AF104942-1|AAD04169.1| 1437|Homo sapiens ABC transporter MOAT-C
protein.
Length = 1437
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 585 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 635
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 636 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 695
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 696 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 753
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 754 IFMKEGCITERGTHE 768
>AF078777-1|AAD47141.1| 748|Homo sapiens ABC transporter protein.
Length = 748
Score = 43.6 bits (98), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 494 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLVSLRRAVGVVPQDAV 552
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 553 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 611
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 612 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 668
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 669 ADEIIVLDQGKVAERGT 685
>AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter
protein.
Length = 842
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 613 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 671
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 672 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 728
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 729 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 787
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 788 VV--NADQILVIKDGCIVERGRHEALLS 813
>AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein.
Length = 511
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 282 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 340
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 341 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 397
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 398 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 456
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 457 VV--NADQILVIKDGCIVERGRHEALLS 482
>AB209454-1|BAD92691.1| 1430|Homo sapiens Multidrug
resistance-associated protein 5 variant protein.
Length = 1430
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 578 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 628
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 629 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 688
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 689 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 746
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 747 IFMKEGCITERGTHE 761
>AB209103-1|BAD92340.1| 799|Homo sapiens ATP-binding cassette C5
splicing variant A variant protein.
Length = 799
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 483 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 533
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 534 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 593
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 594 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 651
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 652 IFMKEGCITERGTHE 666
>AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC
transporter 3 protein.
Length = 842
Score = 43.6 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQ 111
+ G+ A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ
Sbjct: 613 VMPGQTLALVGPSGAGKSTILRLLFRFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQ 671
Query: 112 FDV-FTDSLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXX 166
V F D T+ + + + + GN + + ++ I F V
Sbjct: 672 DTVLFND--TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLS 728
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S
Sbjct: 729 GGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLST 787
Query: 227 DIFKEFNSILLMAEGNLLFHGTQDACKS 254
+ + IL++ +G ++ G +A S
Sbjct: 788 VV--NADQILVIKDGCIVERGRHEALLS 813
>AB019002-1|BAA76608.1| 1437|Homo sapiens MRP5 protein.
Length = 1437
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 585 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 635
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 636 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 695
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 696 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 753
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 754 IFMKEGCITERGTHE 768
>AB005659-1|BAA22887.1| 946|Homo sapiens SMRP protein.
Length = 946
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 13/195 (6%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
I+EG+ I G G+GKT+ + ++ G+ TL EG++ I+G T A + Q +
Sbjct: 94 IQEGKLVGICGSVGSGKTSLISAILGQMTL-LEGSIAISG------TFAYVAQQAWIL-- 144
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS--AHVETXXXXXXXXXXXXXXX 175
+ T+ + ++F E N L + S +
Sbjct: 145 NATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISL 204
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + S+ I I D+P + LD++ + + + K V+ HQ + + +
Sbjct: 205 ARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQ--LQYLVDCDEV 262
Query: 236 LLMAEGNLLFHGTQD 250
+ M EG + GT +
Sbjct: 263 IFMKEGCITERGTHE 277
>BT009918-1|AAP88920.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 499 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 557
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 558 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 616
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 617 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 673
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 674 ADEIIVLDQGKVAERGT 690
>BC006323-1|AAH06323.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 499 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 557
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 558 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 616
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 617 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 673
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 674 ADEIIVLDQGKVAERGT 690
>AL360179-2|CAH70565.1| 752|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 752
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 498 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 556
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 557 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 672
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 673 ADEIIVLDQGKVAERGT 689
>AL360179-1|CAH70564.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 499 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 557
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 558 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 616
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 617 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 673
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 674 ADEIIVLDQGKVAERGT 690
>AL359545-2|CAI41573.1| 752|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 752
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 498 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 556
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 557 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 672
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 673 ADEIIVLDQGKVAERGT 689
>AL359545-1|CAI41574.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 499 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 557
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 558 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 616
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 617 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 673
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 674 ADEIIVLDQGKVAERGT 690
>AF241887-1|AAK20173.1| 752|Homo sapiens ATP binding cassette 7
protein.
Length = 752
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 498 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 556
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 557 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 672
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 673 ADEIIVLDQGKVAERGT 689
>AF133659-1|AAD33045.1| 752|Homo sapiens ATP-binding cassette 7
iron transporter protein.
Length = 752
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 498 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 556
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 557 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 672
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 673 ADEIIVLDQGKVAERGT 689
>AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B
isoform protein.
Length = 893
Score = 43.2 bits (97), Expect = 0.001
Identities = 20/59 (33%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Query: 40 SIWRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
+ W K ++ T+ + +R GE A++GP GAGK++ L ++ G+ P G V+++GR
Sbjct: 7 AFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELA-PSHGLVSVHGR 64
>AB005289-1|BAA28861.1| 752|Homo sapiens ABC transporter 7 protein
protein.
Length = 752
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/197 (19%), Positives = 85/197 (43%), Gaps = 14/197 (7%)
Query: 61 GEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTDSLT 120
G+ AI+G SG+GK+T +V L + P +G++ + G+N++D++ + V
Sbjct: 498 GKKVAIVGGSGSGKST-IVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAV 556
Query: 121 VMEQLVFMTEMKLGNSTKQPNK--------SILNTVIE-EFKLSAHVETXXXXXXXXXXX 171
+ ++ + GN + P + + + ++ V
Sbjct: 557 LFHNTIYY-NLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQ 615
Query: 172 XXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKE 231
A + L +P +++ DE T+ LDS ++G +K + + I H+ S + +
Sbjct: 616 RVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDV-VKHRTSIFIAHRLSTVV--D 672
Query: 232 FNSILLMAEGNLLFHGT 248
+ I+++ +G + GT
Sbjct: 673 ADEIIVLDQGKVAERGT 689
>AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein.
Length = 812
Score = 42.7 bits (96), Expect = 0.002
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDL------TGAEIVPQ 111
I G+ A +G SG GK+T V L + P +G V +G + ++L + IVPQ
Sbjct: 595 IERGKTVAFVGSSGCGKSTS-VQLLQRLYDPVQGQVLFDGVDAKELNVQWLRSQIAIVPQ 653
Query: 112 FDVFTDSLTVMEQLVFMTEMK---LGNSTKQPNKSILNTVIE--EFKLSAHVETXXXXXX 166
V + ++ E + + + L + N + +++ IE K + V
Sbjct: 654 EPVLFNC-SIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGPPEKYNTQVGLKGAQLS 712
Query: 167 XXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSC 226
A + L P+IL+ DE T+ LD+ + V L K + +G+ + H+ S
Sbjct: 713 GGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK-ARTGRTCLVVTHRLSA 771
Query: 227 DIFKEFNSILLMAEGNLLFHGT 248
+ + I+++ G + GT
Sbjct: 772 --IQNADLIVVLHNGKIKEQGT 791
Score = 36.7 bits (81), Expect = 0.10
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 176 ATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFNSI 235
A + + NP+ILI DE T+ LDS + S V L+K S G+ I H+ S + + I
Sbjct: 91 ARALVRNPKILILDEATSALDSESESAVQAALEKAS-KGRTTIVVAHRLS--TIRSADLI 147
Query: 236 LLMAEGNLLFHG 247
+ + +G L G
Sbjct: 148 VTLKDGMLAEKG 159
>M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis transmembrane
conductance regulator protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic
fibrosis mRNA, encoding a presumed transmembrane
conductance regulator (CFTR). ).
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1195 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1252
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1253 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1311
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1312 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1371
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1372 QAFADCTVILC 1382
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 427 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 469
>DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1195 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1252
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1253 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1311
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1312 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1371
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1372 QAFADCTVILC 1382
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 427 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 469
>DQ356257-1|ABC87053.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 1213 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 1270
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 1271 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 1329
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 1330 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 1389
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 1390 QAFADCTVILC 1400
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>AY848829-1|AAW33656.1| 258|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
subfam protein.
Length = 258
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 57 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 114
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 115 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 173
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 174 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 233
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 234 QAFADCTVILC 244
>AC000061-1|AAB46340.2| 484|Homo sapiens unknown protein.
Length = 484
Score = 41.1 bits (92), Expect = 0.005
Identities = 48/191 (25%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 39 KSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN 96
K + K + I++N I G+ ++G +G+GK+T L + L EG + I+
Sbjct: 217 KDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR--LLNTEGEIQID 274
Query: 97 GRNVRDLTGAE------IVPQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIE 150
G + +T + ++PQ VF S T + L + K ++ L +VIE
Sbjct: 275 GVSWDSITLQQWRKAFGVIPQ-KVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIE 333
Query: 151 EF--KLSAHVETXXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILK 208
+F KL + A S LS +IL+ DEP+ LD + LK
Sbjct: 334 QFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLK 393
Query: 209 KLSASGKIVIC 219
+ A +++C
Sbjct: 394 QAFADCTVILC 404
>AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens
cDNA FLJ23973 fis, clone HEP18305, highly similar to
ATP-binding cassette, sub-family B, member 6,
mitochondrial precursor. ).
Length = 571
Score = 40.3 bits (90), Expect = 0.008
Identities = 50/201 (24%), Positives = 88/201 (43%), Gaps = 18/201 (8%)
Query: 65 AIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQFDV-FTD 117
A++GPSGAGK+T L L + G + I+G+++ +T A +VPQ V F D
Sbjct: 349 ALVGPSGAGKSTILRLLFLFYDIS-SGCIRIDGQDISQVTQASLRSHIGVVPQDTVLFND 407
Query: 118 SLTVMEQLVFMTEMKLGNSTKQ--PNKSILNTVIEEFK--LSAHVETXXXXXXXXXXXXX 173
T+ + + + + GN + + ++ I F V
Sbjct: 408 --TIADNIRY-GRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSGGEKQRV 464
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + L P I++ DE T+ LD+ N + L K+ A+ + I H+ S + +
Sbjct: 465 AIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCAN-RTTIVVAHRLSTVV--NAD 521
Query: 234 SILLMAEGNLLFHGTQDACKS 254
IL++ +G ++ G +A S
Sbjct: 522 QILVIKDGCIVERGRHEALLS 542
>AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ33951 fis, clone CTONG2018483, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 293
Score = 39.1 bits (87), Expect = 0.020
Identities = 31/148 (20%), Positives = 57/148 (38%), Gaps = 5/148 (3%)
Query: 110 PQFDVFTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAHVETXXXXXXXXX 169
PQ D + LT E L + ++ +Q + +I L AH +
Sbjct: 39 PQQDALDELLTGWEHLYYYCSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGT 96
Query: 170 XXXXXXATSFLSNPQILICDEPTTGLDSYNASQV-IGILKKLSASGKIVICSVHQPSCDI 228
A + + P IL+ DEP++G+D + + I+K++ V+ S C+
Sbjct: 97 KRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEA 156
Query: 229 FKEFNSILLMAEGNLLFHGTQDACKSFF 256
+ +M G+ G+ K+ F
Sbjct: 157 L--CTRLAIMVNGSFKCLGSPQHIKNRF 182
>AY196326-1|AAO40749.1| 930|Homo sapiens truncated ABCC12 protein
protein.
Length = 930
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 445 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 497
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 498 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 553
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 554 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 611
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 612 EVILLEDGEICEKGT 626
>AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette
transporter sub-family C member 12 protein.
Length = 1359
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 555
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 556 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 611
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 612 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 669
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 670 EVILLEDGEICEKGT 684
>AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette
protein C12 isoform D protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 555
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 556 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 611
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 612 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 669
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 670 EVILLEDGEICEKGT 684
>AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette
protein C12 isoform C-p1 protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 555
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 556 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 611
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 612 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 669
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 670 EVILLEDGEICEKGT 684
>AF395909-1|AAL79529.1| 935|Homo sapiens ATP-binding cassette
protein C12 isoform B protein.
Length = 935
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 555
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 556 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 611
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 612 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 669
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 670 EVILLEDGEICEKGT 684
>AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette
protein C12 isoform A protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.060
Identities = 42/195 (21%), Positives = 79/195 (40%), Gaps = 17/195 (8%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDVFTD 117
+R+G+ I G G+GK++ L +L G+ L +G V +NG T A + Q +F
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG------TLAYVSQQAWIFHG 555
Query: 118 SLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLS----AHVETXXXXXXXXXXXXX 173
+ V E ++F K + Q + + L +
Sbjct: 556 N--VRENILF--GEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRI 611
Query: 174 XXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICSVHQPSCDIFKEFN 233
A + S+ Q+ + D+P + +D++ V K + GK V+ HQ + +
Sbjct: 612 SLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQ--LQFLESCD 669
Query: 234 SILLMAEGNLLFHGT 248
++L+ +G + GT
Sbjct: 670 EVILLEDGEICEKGT 684
>U91318-3|AAC15785.1| 848|Homo sapiens Gene product with similarity
to Multidrug resistance protein MRP1 protein.
Length = 848
Score = 36.7 bits (81), Expect = 0.10
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N + +G A++GP GAGK++ L +L G+ + EG V+I G VPQ +
Sbjct: 608 NLTVPQGCLLAVVGPVGAGKSSLLSALLGELS-KVEGFVSIEG-------AVAYVPQ-EA 658
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAH--VETXXXXXXXXXXXX 172
+ + +V+E + F E+ + L ++ F H +
Sbjct: 659 WVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQR 718
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNA----SQVIGILKKLSASGKIVICSVHQPSCDI 228
A + + + D+P LD++ +QVIG L + +I++ H + I
Sbjct: 719 LSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILV--TH--ALHI 774
Query: 229 FKEFNSILLMAEGNLLFHGT 248
+ + I+++A G + G+
Sbjct: 775 LPQADWIIVLANGAIAEMGS 794
>BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 6 protein.
Length = 1503
Score = 36.7 bits (81), Expect = 0.10
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N + +G A++GP GAGK++ L +L G+ + EG V+I G VPQ +
Sbjct: 650 NLTVPQGCLLAVVGPVGAGKSSLLSALLGELS-KVEGFVSIEG-------AVAYVPQ-EA 700
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAH--VETXXXXXXXXXXXX 172
+ + +V+E + F E+ + L ++ F H +
Sbjct: 701 WVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQR 760
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNA----SQVIGILKKLSASGKIVICSVHQPSCDI 228
A + + + D+P LD++ +QVIG L + +I++ H + I
Sbjct: 761 LSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILV--TH--ALHI 816
Query: 229 FKEFNSILLMAEGNLLFHGT 248
+ + I+++A G + G+
Sbjct: 817 LPQADWIIVLANGAIAEMGS 836
>AY848830-1|AAW33657.1| 241|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
subfam protein.
Length = 241
Score = 36.7 bits (81), Expect = 0.10
Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 11/162 (6%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVPQFDVFTDSL 119
++G +G+GK+T L + L EG + I+G + +T + ++PQ VF S
Sbjct: 3 LLGRTGSGKSTLLSAFLR--LLNTEGEIQIDGVSWDSITLQQWRKAFGVIPQ-KVFIFSG 59
Query: 120 TVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEF--KLSAHVETXXXXXXXXXXXXXXXAT 177
T + L + K ++ L +VIE+F KL + A
Sbjct: 60 TFRKNLDPYEQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLAR 119
Query: 178 SFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVIC 219
S LS +IL+ DEP+ LD + LK+ A +++C
Sbjct: 120 SVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFADCTVILC 161
>AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic
anion tranporter-E protein.
Length = 1503
Score = 36.7 bits (81), Expect = 0.10
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N + +G A++GP GAGK++ L +L G+ + EG V+I G VPQ +
Sbjct: 650 NLTVPQGCLLAVVGPVGAGKSSLLSALLGELS-KVEGFVSIEG-------AVAYVPQ-EA 700
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAH--VETXXXXXXXXXXXX 172
+ + +V+E + F E+ + L ++ F H +
Sbjct: 701 WVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQR 760
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNA----SQVIGILKKLSASGKIVICSVHQPSCDI 228
A + + + D+P LD++ +QVIG L + +I++ H + I
Sbjct: 761 LSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILV--TH--ALHI 816
Query: 229 FKEFNSILLMAEGNLLFHGT 248
+ + I+++A G + G+
Sbjct: 817 LPQADWIIVLANGAIAEMGS 836
>AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein.
Length = 1503
Score = 36.7 bits (81), Expect = 0.10
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 19/200 (9%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAEIVPQFDV 114
N + +G A++GP GAGK++ L +L G+ + EG V+I G VPQ +
Sbjct: 650 NLTVPQGCLLAVVGPVGAGKSSLLSALLGELS-KVEGFVSIEG-------AVAYVPQ-EA 700
Query: 115 FTDSLTVMEQLVFMTEMKLGNSTKQPNKSILNTVIEEFKLSAH--VETXXXXXXXXXXXX 172
+ + +V+E + F E+ + L ++ F H +
Sbjct: 701 WVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQR 760
Query: 173 XXXATSFLSNPQILICDEPTTGLDSYNA----SQVIGILKKLSASGKIVICSVHQPSCDI 228
A + + + D+P LD++ +QVIG L + +I++ H + I
Sbjct: 761 LSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILV--TH--ALHI 816
Query: 229 FKEFNSILLMAEGNLLFHGT 248
+ + I+++A G + G+
Sbjct: 817 LPQADWIIVLANGAIAEMGS 836
>X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA)
protein.
Length = 431
Score = 36.3 bits (80), Expect = 0.14
Identities = 44/208 (21%), Positives = 85/208 (40%), Gaps = 21/208 (10%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTIN-------GRNVRDLTGAEIVP 110
+++G+ A++G SG GK+T +V L + P GTV ++ G+ + L +
Sbjct: 204 VKKGQTLALVGSSGCGKST-VVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRA 262
Query: 111 QFDVFTDS-----LTVMEQLVFMTEMKLGNSTK---QPNKSILNTVIEEF--KLSAHVET 160
Q + + ++ E + + ++ + + + ++ IE K V
Sbjct: 263 QLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGD 322
Query: 161 XXXXXXXXXXXXXXXATSFLSNPQILICDEPTTGLDSYNASQVIGILKKLSASGKIVICS 220
A + + PQIL+ DE T+ LD+ + V L K + G+ I
Sbjct: 323 KGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK-AREGRTCIVI 381
Query: 221 VHQPSCDIFKEFNSILLMAEGNLLFHGT 248
H+ S + + I++ G + HGT
Sbjct: 382 AHRLS--TIQNADLIVVFQNGRVKEHGT 407
>AB208839-1|BAD92076.1| 403|Homo sapiens ATP-binding cassette,
sub-family A member 1 variant protein.
Length = 403
Score = 36.3 bits (80), Expect = 0.14
Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 11/103 (10%)
Query: 37 EEKSIWRKVAKPKTVIIDNAC--IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVT 94
E I+R+ KP +D C I GE ++G +GAGK++ L G T+ G
Sbjct: 234 ELTKIYRRKRKPA---VDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVT-RGDAF 289
Query: 95 INGR----NVRDL-TGAEIVPQFDVFTDSLTVMEQLVFMTEMK 132
+N N+ ++ PQFD T+ LT E + F ++
Sbjct: 290 LNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLR 332
>DQ388136-1|ABD72199.1| 1321|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1321
Score = 34.7 bits (76), Expect = 0.42
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMMIMGELE-PSEGKIKHSGR 487
>DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>AK097044-1|BAC04933.1| 199|Homo sapiens protein ( Homo sapiens
cDNA FLJ39725 fis, clone SMINT2015294, highly similar to
Mus musculus ATP-dependent zinc metalloprotease (Afg3l1)
mRNA. ).
Length = 199
Score = 34.3 bits (75), Expect = 0.56
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 44 KVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
+V ++V + A E A + GP G GKT + AG+ T+PF +T+NG
Sbjct: 81 EVVNKQSVRVIPAPGTSSEGAMLTGPPGTGKTLLAKATAGEATVPF---ITVNG 131
>AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein.
Length = 996
Score = 34.3 bits (75), Expect = 0.56
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 55 NACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
N I G+ A+ G +GAGKT+ L+ + G+ P EG + +GR
Sbjct: 445 NFKIERGQLLAVAGSTGAGKTSLLMVIMGELE-PSEGKIKHSGR 487
>AY032599-1|AAK39642.1| 1463|Homo sapiens multidrug
resistance-associated protein 7 protein.
Length = 1463
Score = 33.5 bits (73), Expect = 0.97
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 1240 CVQPGEKVGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 1298
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 1299 Q-EPFLFSGTVRENL 1312
>BC024103-1|AAH24103.1| 282|Homo sapiens ABCC10 protein protein.
Length = 282
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 59 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 117
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 118 Q-EPFLFSGTVRENL 131
>BC021245-1|AAH21245.2| 122|Homo sapiens AFG3L1 protein protein.
Length = 122
Score = 33.1 bits (72), Expect = 1.3
Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
Query: 64 AAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
A + GP G GKT + AG+ T+PF +T+NG
Sbjct: 24 AMLTGPPGTGKTLLAKATAGEATVPF---ITVNG 54
>AL359813-5|CAI23220.1| 157|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 10 protein.
Length = 157
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 20 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 78
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 79 Q-EPFLFSGTVRENL 92
>AL359813-4|CAI23219.1| 172|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 10 protein.
Length = 172
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 40 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 98
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 99 Q-EPFLFSGTVRENL 112
>AL359813-2|CAI23217.1| 1492|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 10 protein.
Length = 1492
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 1269 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 1327
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 1328 Q-EPFLFSGTVRENL 1341
Score = 30.3 bits (65), Expect = 9.1
Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Query: 42 WRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
W V I + +++G I+G G GK++ L ++AG+ G V + G
Sbjct: 607 WDPVGTSLETFISHLEVKKGMLVGIVGKVGCGKSSLLAAIAGELH-RLRGHVAVRG 661
>AL133613-1|CAB63742.1| 700|Homo sapiens hypothetical protein
protein.
Length = 700
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 477 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 535
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 536 Q-EPFLFSGTVRENL 549
>AK024446-1|BAB15736.1| 706|Homo sapiens FLJ00036 protein protein.
Length = 706
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 483 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 541
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 542 Q-EPFLFSGTVRENL 555
>AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens
cDNA FLJ14297 fis, clone PLACE1008941. ).
Length = 156
Score = 33.1 bits (72), Expect = 1.3
Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
+ + E ++G +GAGK+T + + G CT+P G V + G
Sbjct: 88 VLKSEVLGLLGHNGAGKSTSIKMITG-CTVPTAGVVVLQG 126
>AK000002-1|BAA92227.1| 1513|Homo sapiens FLJ00002 protein protein.
Length = 1513
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 57 CIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGRNVRDLTGAE------IVP 110
C++ GE I+G +G+GK++ L+ L + P G V ++G + L A+ I+P
Sbjct: 1290 CVQPGEKLGIVGRTGSGKSSLLLVLF-RLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIP 1348
Query: 111 QFDVFTDSLTVMEQL 125
Q + F S TV E L
Sbjct: 1349 Q-EPFLFSGTVRENL 1362
Score = 30.3 bits (65), Expect = 9.1
Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Query: 42 WRKVAKPKTVIIDNACIREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
W V I + +++G I+G G GK++ L ++AG+ G V + G
Sbjct: 628 WDPVGTSLETFISHLEVKKGMLVGIVGKVGCGKSSLLAAIAGELH-RLRGHVAVRG 682
>AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein.
Length = 156
Score = 33.1 bits (72), Expect = 1.3
Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
+ + E ++G +GAGK+T + + G CT+P G V + G
Sbjct: 88 VLKSEVLGLLGHNGAGKSTSIKMITG-CTVPTAGVVVLQG 126
>BX248518-7|CAM26017.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 656 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 687
>BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 618 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 649
>BX119957-3|CAM25907.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 656 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 687
>BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 618 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 649
>BX000357-8|CAI18563.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 656 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 687
>BX000357-6|CAI18562.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 618 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 649
>BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 656 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 687
>BC036378-1|AAH36378.1| 633|Homo sapiens ABCC12 protein protein.
Length = 633
Score = 32.7 bits (71), Expect = 1.7
Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 58 IREGEFAAIIGPSGAGKTTFLVSLAGKCTLPFEGTVTING 97
+R+G+ I G G+GK++ L +L G+ L +G V +NG
Sbjct: 503 VRKGKILGICGNVGSGKSSLLAALLGQMQLQ-KGVVAVNG 541
>BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 32.7 bits (71), Expect = 1.7
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 66 IIGPSGAGKTTFLVSLAGKCTLPFEGTVTINGR 98
I+GP+G GK+T L+ L GK T P G + N R
Sbjct: 656 IVGPNGVGKSTLLLLLTGKLT-PTHGEMRKNHR 687
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.135 0.394
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,120,657
Number of Sequences: 224733
Number of extensions: 1649583
Number of successful extensions: 4815
Number of sequences better than 10.0: 344
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 174
Number of HSP's that attempted gapping in prelim test: 4085
Number of HSP's gapped (non-prelim): 613
length of query: 312
length of database: 73,234,838
effective HSP length: 90
effective length of query: 222
effective length of database: 53,008,868
effective search space: 11767968696
effective search space used: 11767968696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 65 (30.3 bits)
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