Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002698-TA|BGIBMGA002698-PA|IPR002018|Carboxylesterase,
type B
(650 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipas... 166 2e-40
X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for ... 164 1e-39
M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase pro... 164 1e-39
M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase prot... 164 1e-39
M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipas... 164 1e-39
AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase (... 164 1e-39
AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lip... 164 1e-39
AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase p... 164 1e-39
BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein. 162 4e-39
Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein. 149 3e-35
U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein. 149 3e-35
D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precurso... 149 3e-35
BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2 (int... 149 3e-35
AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2 (int... 149 3e-35
BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked ... 149 4e-35
BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked ... 149 4e-35
AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isof... 149 4e-35
AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein. 149 4e-35
BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein. 145 5e-34
BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein. 145 5e-34
BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked ... 144 9e-34
AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein. 144 9e-34
AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein. 144 9e-34
M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase prot... 142 3e-33
BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase, i... 142 3e-33
BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Y... 142 3e-33
BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein. 142 3e-33
AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (Y... 142 3e-33
AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related acety... 142 3e-33
AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein. 142 3e-33
AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein. 142 3e-33
BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein. 142 3e-33
AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein. 141 6e-33
AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase is... 141 8e-33
BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein. 139 3e-32
AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein. 139 3e-32
BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein. 138 7e-32
AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HN... 137 1e-31
BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein. 136 2e-31
AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform pr... 136 2e-31
AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform pr... 136 2e-31
AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein. 136 2e-31
AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase ... 136 2e-31
BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein. 136 2e-31
AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo pr... 136 3e-31
M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase pro... 135 5e-31
M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein. 135 5e-31
M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein. 135 5e-31
BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase p... 135 5e-31
AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein. 135 5e-31
AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein. 134 1e-30
AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase ... 126 2e-28
AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HN... 126 2e-28
M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein. 126 3e-28
D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein. 126 3e-28
BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1 (mon... 126 3e-28
AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein. 126 3e-28
AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b p... 126 3e-28
AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a p... 126 3e-28
AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b p... 126 3e-28
AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a p... 126 3e-28
L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein. 125 4e-28
BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein. 125 6e-28
BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1 (mon... 125 6e-28
S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholester... 124 1e-27
BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein pr... 124 1e-27
AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester hydro... 124 1e-27
AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase ... 124 1e-27
BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein. 124 1e-27
L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein. 123 2e-27
AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo pr... 122 5e-27
M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein. 120 2e-26
AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-relate... 119 3e-26
X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage serin... 119 4e-26
BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein. 119 4e-26
BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7 prot... 119 4e-26
BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein. 119 4e-26
AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5 prot... 119 4e-26
AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens ... 119 4e-26
AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens ... 119 4e-26
M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein. 115 6e-25
AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens ... 101 1e-20
BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein. 99 6e-20
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein. 93 4e-18
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor... 91 8e-18
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein. 91 1e-17
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein. 91 1e-17
AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens ... 90 2e-17
BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for IM... 87 2e-16
AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein. 56 4e-07
BC042923-1|AAH42923.1| 2541|Homo sapiens talin 1 protein. 34 1.4
AF178534-1|AAF27330.1| 2540|Homo sapiens talin protein. 34 1.4
AB028950-1|BAA82979.2| 2550|Homo sapiens KIAA1027 protein protein. 34 1.4
AF177198-1|AAF23322.1| 2541|Homo sapiens talin protein. 33 2.4
AF078828-1|AAD13152.1| 2541|Homo sapiens talin protein. 33 2.4
AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein. 33 3.2
AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing ox... 33 3.2
AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein. 33 3.2
AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein. 33 3.2
AF217490-1|AAF78197.1| 191|Homo sapiens fragile 16D oxido reduc... 33 3.2
AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing pr... 33 3.2
AK129776-1|BAC85232.1| 472|Homo sapiens protein ( Homo sapiens ... 31 9.6
>S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipase
protein.
Length = 742
Score = 166 bits (404), Expect = 2e-40
Identities = 142/483 (29%), Positives = 217/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 50 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 106
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 107 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 166
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 167 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 226
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AA
Sbjct: 227 PYNKGLIRAAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPAA- 285
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ V ++ L + + E FI P L I ++ G +G I
Sbjct: 286 VTVAYKVPLAGLEYPMLHYVGFVPVIDEDFIPADPIN--LYANAADIDYIAGTNNMDGHI 343
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFNIED 389
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 344 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 402
Query: 390 -YLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 403 IVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 458
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 459 IQYVFGKPFATPTGYRPQDRTVFKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 518
Query: 504 LRI 506
L I
Sbjct: 519 LEI 521
>X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for
bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
Length = 745
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 405
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 406 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 461
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 462 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 521
Query: 504 LRI 506
L I
Sbjct: 522 LEI 524
>M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 405
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 406 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 461
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 462 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 521
Query: 504 LRI 506
L I
Sbjct: 522 LEI 524
>M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase
protein.
Length = 747
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 405
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 406 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 461
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 462 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 521
Query: 504 LRI 506
L I
Sbjct: 522 LEI 524
>M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipase
protein.
Length = 742
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 50 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 106
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 107 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 166
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 167 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 226
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 227 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 286
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 287 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 343
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 344 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 402
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 403 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 458
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 459 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 518
Query: 504 LRI 506
L I
Sbjct: 519 LEI 521
>AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase
(bile salt-stimulated lipase) protein.
Length = 756
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 405
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 406 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 461
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 462 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 521
Query: 504 LRI 506
L I
Sbjct: 522 LEI 524
>AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lipase
oncofetal isoform protein.
Length = 612
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 30 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 86
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 87 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 146
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 147 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 206
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 207 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 266
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 267 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 323
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 324 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 382
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 383 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 438
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 439 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 498
Query: 504 LRI 506
L I
Sbjct: 499 LEI 501
>AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 164 bits (398), Expect = 1e-39
Identities = 140/483 (28%), Positives = 216/483 (44%), Gaps = 32/483 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-IE 388
A+ + + + DF + +F +G A+ D Y ++ + S N +
Sbjct: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKKK 405
Query: 389 DYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEE 447
+ + D + LV Y Y FS+ + V P V A H+++
Sbjct: 406 TVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHADD 461
Query: 448 LAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNHY 503
+ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+ Y
Sbjct: 462 IQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGY 521
Query: 504 LRI 506
L I
Sbjct: 522 LEI 524
>BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein.
Length = 722
Score = 162 bits (393), Expect = 4e-39
Identities = 141/484 (29%), Positives = 217/484 (44%), Gaps = 35/484 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGV--GYEGTEDCLVVDVL 102
F GIP+A T + P P ++G A +C++ G EDCL +++
Sbjct: 53 FKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIW 109
Query: 103 TPN--LDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD---------VVVVSINFRES 151
P + LPVM+W+ G F +F N D V+VV+ N+R
Sbjct: 110 VPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVG 169
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
LGFL G PGN GL+D + WVK NIA FGG+P+++TLFG +G A+V L TLS
Sbjct: 170 PLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 229
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAAL 271
P GL+ +AI+QSG A +PW + ++ L +A +VAE +G V + +++ T AL
Sbjct: 230 PYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 272 MAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+ ++ L + + FI P L I ++ G +G I
Sbjct: 290 -TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPIN--LYANAADIDYIAGTNNMDGHI 346
Query: 332 RATEAIEHDWLQRMETSF-PDFLQPDLQFENAEGESAIAEEIKDFYFKN--ELISMFN-I 387
A +I+ + + DF + +F +G A+ D Y ++ + S N
Sbjct: 347 FA--SIDMPAINKGNKKVTEDFYKLVSEFTITKGLRG-AKTTFDVYTESWAQDPSQENKK 403
Query: 388 EDYLSYHGDTMILV-XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSE 446
+ + + D + LV Y Y FS+ + V P V A H++
Sbjct: 404 KTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMP---VYPKWV-GADHAD 459
Query: 447 ELAYMFYE--KSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVV--WRPFTTENNH 502
++ Y+F + + D T+ ++ WTNFAKTG P S V W P+TTEN+
Sbjct: 460 DIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSG 519
Query: 503 YLRI 506
YL I
Sbjct: 520 YLEI 523
>Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein.
Length = 559
Score = 149 bits (361), Expect = 3e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 18 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 77
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 78 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 137
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 138 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 196
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 197 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 256
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 257 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 305
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 306 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 364
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 365 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 420
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 421 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 478
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 479 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 520
>U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein.
Length = 550
Score = 149 bits (361), Expect = 3e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 9 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 68
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 69 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 128
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 129 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 187
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 188 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 247
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 248 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 296
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 297 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 355
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 356 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 411
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 412 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 469
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 470 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 511
>D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precursor
protein.
Length = 559
Score = 149 bits (361), Expect = 3e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 18 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 77
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 78 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 137
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 138 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 196
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 197 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 256
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 257 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 305
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 306 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 364
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 365 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 420
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 421 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 478
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 479 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 520
>BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 149 bits (361), Expect = 3e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 82 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 141
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 142 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 201
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 202 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 260
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 261 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 320
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 321 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 369
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 370 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 428
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 429 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 484
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 485 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 542
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 543 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 584
>AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 149 bits (361), Expect = 3e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 82 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 141
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 142 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 201
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 202 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 260
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 261 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 320
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 321 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 369
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 370 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 428
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 429 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 484
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 485 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 542
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 543 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 584
>BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 149 bits (360), Expect = 4e-35
Identities = 135/507 (26%), Positives = 215/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P SP + G A
Sbjct: 44 QYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNA 103
Query: 76 NRRDVKCVRPLGVGY----------------------EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + + EDCL +++ P D
Sbjct: 104 TQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQN 163
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 164 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 223
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 284 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFG 341
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 342 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 394
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 395 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 453
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 454 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 509
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 510 CNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 149 bits (360), Expect = 4e-35
Identities = 135/507 (26%), Positives = 215/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P SP + G A
Sbjct: 44 QYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNA 103
Query: 76 NRRDVKCVRPLGVGY----------------------EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + + EDCL +++ P D
Sbjct: 104 TQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQN 163
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 164 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 223
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 284 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFG 341
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 342 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 394
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 395 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 453
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 454 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 509
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 510 CNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isoform
1 variant protein.
Length = 582
Score = 149 bits (360), Expect = 4e-35
Identities = 141/524 (26%), Positives = 214/524 (40%), Gaps = 47/524 (8%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 41 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 100
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 101 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 160
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 161 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 219
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 220 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 279
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 280 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 328
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWLQRME 346
P + F+ + P + + +F +P + G NE G + +D + M+
Sbjct: 329 -PFKMIPGVVDGVFLPRHPKELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMD 387
Query: 347 TSFPD-FLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXX 405
LQ L + +++ Y + + D+M ++
Sbjct: 388 REASQAALQKMLTLLML--PPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVI--PA 443
Query: 406 XXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLL-- 463
PVY Y+F + S K P A H +EL ++F N
Sbjct: 444 LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHM--KADHGDELPFVFRSFFGGNYIKFTE 501
Query: 464 -DLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + +++ W NFA+ G P E W P + YL++
Sbjct: 502 EEEQLSRKMMKYWANFARNGNPNGE-GLPHW-PLFDQEEQYLQL 543
>AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein.
Length = 816
Score = 149 bits (360), Expect = 4e-35
Identities = 135/507 (26%), Positives = 215/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P SP + G A
Sbjct: 44 QYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNA 103
Query: 76 NRRDVKCVRPLGVGY----------------------EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + + EDCL +++ P D
Sbjct: 104 TQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQN 163
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 164 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 223
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 284 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFG 341
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 342 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 394
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 395 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 453
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 454 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 509
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 510 CNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein.
Length = 587
Score = 145 bits (351), Expect = 5e-34
Identities = 107/341 (31%), Positives = 153/341 (44%), Gaps = 34/341 (9%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 62 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 121
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 122 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 181
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 182 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 240
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 241 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 300
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 301 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 349
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE 328
P + F+ + P + + +F +P + G NE
Sbjct: 350 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNE 389
>BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein.
Length = 586
Score = 145 bits (351), Expect = 5e-34
Identities = 107/341 (31%), Positives = 153/341 (44%), Gaps = 34/341 (9%)
Query: 9 LLFFASISGEDFELPIVNIGQGAVLGSHAH----DGEYFTFYGIPYADSTSGPHRFKAPS 64
LL G+D PI G VLGS H + TF GIP+A GP RF P
Sbjct: 61 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPE 120
Query: 65 SPPKFEGAFVANRRDVKCVRPL-GVGYEG-------------TEDCLVVDVLTP-NLDAA 109
P + G C++ L V E +EDCL + + TP +
Sbjct: 121 PPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEG 180
Query: 110 AQLPVMVWVKGKE--FDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNA 167
+ LPVMVW+ G F D S ++ +VVVV I +R +LGF G + A GN
Sbjct: 181 SNLPVMVWIHGGALVFGMASLYDGSMLAALE-NVVVVIIQYRLGVLGFFSTGDKHATGNW 239
Query: 168 GLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGN 227
G D +A L+WV++NIAHFGGNPD VT+FG +G +V + +SP++ GL H AI +SG
Sbjct: 240 GYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGV 299
Query: 228 AFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAF 287
A P + A+ + +V N+ ++ + V L E L N
Sbjct: 300 ALLPGLIASS--------ADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINK--- 348
Query: 288 APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENE 328
P + F+ + P + + +F +P + G NE
Sbjct: 349 -PFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNE 388
>BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked
protein.
Length = 816
Score = 144 bits (349), Expect = 9e-34
Identities = 134/507 (26%), Positives = 214/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P P + G
Sbjct: 44 QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNT 103
Query: 76 NRRDVKCVRPLG--------------------VGY--EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + Y + EDCL +++ P D
Sbjct: 104 TQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQN 163
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 164 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 223
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 284 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFG 341
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 342 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 394
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 395 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 453
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 454 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 509
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 510 CNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein.
Length = 816
Score = 144 bits (349), Expect = 9e-34
Identities = 134/507 (26%), Positives = 214/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P P + G
Sbjct: 44 QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNT 103
Query: 76 NRRDVKCVRPLG--------------------VGY--EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + Y + EDCL +++ P D
Sbjct: 104 TQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQN 163
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 164 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 223
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 284 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFG 341
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 342 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 394
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 395 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 453
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 454 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 509
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 510 CNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein.
Length = 817
Score = 144 bits (349), Expect = 9e-34
Identities = 134/507 (26%), Positives = 214/507 (42%), Gaps = 57/507 (11%)
Query: 21 ELPIVNIGQGAVLGSHAHD-----GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
+ P+VN G + G G + G+PYA +G RF+ P P + G
Sbjct: 45 QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNT 104
Query: 76 NRRDVKCVRPLG--------------------VGY--EGTEDCLVVDVLTPNLDAA---- 109
+ C + L + Y + EDCL +++ P D
Sbjct: 105 TQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQN 164
Query: 110 AQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAG 168
++ PVMV++ G + + N +V+V++IN+R ILGFL G + A GN G
Sbjct: 165 SKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYG 224
Query: 169 LKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA 228
L D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A
Sbjct: 225 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 284
Query: 229 FAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFA 288
+ WAV Y +A+ +G + + ++ E + L + + +AF
Sbjct: 285 LSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL--IQQTITPATYHIAFG 342
Query: 289 PCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRME 346
P ++ + I P + GEFL M G + EG ++ + I D + +
Sbjct: 343 PVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPND 395
Query: 347 TSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXX 404
F D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 396 FDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPA 454
Query: 405 XXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSD 457
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 455 VATADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFS 510
Query: 458 DNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 511 CNFSKNDVMLSAVVMTYWTNFAKTGDP 537
>M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase
protein.
Length = 614
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase,
isoform E4-E5 precursor protein.
Length = 617
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Yt
blood group) protein.
Length = 617
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein.
Length = 546
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (YT
blood group) protein.
Length = 617
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related
acetylcholinesterase protein.
Length = 526
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein.
Length = 617
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein.
Length = 614
Score = 142 bits (345), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein.
Length = 640
Score = 142 bits (344), Expect = 3e-33
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVIVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + A L H+V
Sbjct: 272 MGEARRRATQLAHLV 286
>AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein.
Length = 835
Score = 141 bits (342), Expect = 6e-33
Identities = 115/392 (29%), Positives = 172/392 (43%), Gaps = 39/392 (9%)
Query: 140 DVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHG 199
+V+V ++N+R +LGFL G + A GN GL D I L+W+ ENIAHFGG+P+ +T+FG G
Sbjct: 206 NVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSG 265
Query: 200 SGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQEL 259
+GA+ V+L+ LS + GL KAIAQSG A + W+V L Y +A +G + E
Sbjct: 266 AGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEA 325
Query: 260 SEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIP 319
E R L V ++ +AF P ++ + + P + GEFL
Sbjct: 326 VECLRRKPSREL--VDQDVQPARYHIAFGPVVDGDV------VPDDPEILMQQGEFLNYD 377
Query: 320 FMTGFVENEGTIRATEAIE-HDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFY-- 376
+ G + EG ++ E D + F D + EG+ + E IK Y
Sbjct: 378 MLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTD 437
Query: 377 FKNELISMFNIEDYLSYHGDTMILVXXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVG 435
+ + + L+ D V PVY Y F + + G+P
Sbjct: 438 WADRDNGEMRRKTLLALFTDHQ-WVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRP--- 493
Query: 436 PIQVDAAAHSEELAYMF-------YEKSDDNIPLLDLTIGDILVERWTNFAKTGAPVSET 488
+ AAH +EL Y+F + N D+ + +++ WTNFAKTG P
Sbjct: 494 --EWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 551
Query: 489 SQ--------------VVWRPFTTENNHYLRI 506
Q VVW F ++ YL I
Sbjct: 552 PQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHI 583
Score = 38.3 bits (85), Expect = 0.084
Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 12/109 (11%)
Query: 8 PLLFFASISGEDFELPIVNIGQGAVLG-----SHAHDGEYFTFYGIPYADSTSGPHRFKA 62
P L S+ E F P+VN G V G ++ G F G+PYA G RF+
Sbjct: 29 PGLGLGSLGEERF--PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQP 86
Query: 63 PSSPPKFEGAFVANRRDVKCVRPLGVGYEGTEDCLVVDV-LTPNLDAAA 110
P +P + G A C + L G +++ V T NL+AAA
Sbjct: 87 PEAPASWPGVRNATTLPPACPQNL----HGALPAIMLPVWFTDNLEAAA 131
>AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase
isoform E4-E6 precursor variant protein.
Length = 614
Score = 141 bits (341), Expect = 8e-33
Identities = 97/255 (38%), Positives = 129/255 (50%), Gaps = 22/255 (8%)
Query: 18 EDFELPIVNIGQGAVLGSHAHD--GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVA 75
ED EL +V + G + G G F GIP+A+ GP RF P + G A
Sbjct: 35 EDAEL-LVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDA 93
Query: 76 NRRDVKC---VRPLGVGYEGTE----------DCLVVDVLTPNLDAAAQLPVMVWVKGKE 122
C V L G+EGTE DCL ++V TP + PV+VW+ G
Sbjct: 94 TTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGG 153
Query: 123 FDSEYNQ--DFSFRNFVQKD-VVVVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKW 178
F S + + R VQ + V+VS+N+R GFL L G+ APGN GL D L+W
Sbjct: 154 FYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQW 213
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V+EN+A FGG+P VTLFG +GAA+V + LSP + GL H+A+ QSG PWA
Sbjct: 214 VQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV--G 271
Query: 239 LNYAIQVAEALGHIV 253
+ A + L H+V
Sbjct: 272 MGEARRRTTQLAHLV 286
>BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein.
Length = 823
Score = 139 bits (336), Expect = 3e-32
Identities = 132/492 (26%), Positives = 204/492 (41%), Gaps = 61/492 (12%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVG---------- 89
G F G+PYA +G RF+ P P + A + C + + G
Sbjct: 75 GPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVW 134
Query: 90 ------------YEGTEDCLVVDVLTPN----LDAAAQLPVMVWVKGKEFDSEYNQDFSF 133
+ +EDCL +++ P D+ PVMV++ G + +
Sbjct: 135 FTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDG 194
Query: 134 RNFVQK-DVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDD 192
+V+V+++N+R +LGFL G + A GN GL D+I L+W ENI FGG+P
Sbjct: 195 SVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLR 254
Query: 193 VTLFGHGSGAAAVDLVTLSPLA---------NGLVHKAIAQSGNAFAPWAVTRDNLNYAI 243
+T+FG G+G + V+L+TLS + GL +AIAQSG A + WAV+ YA
Sbjct: 255 ITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYAR 314
Query: 244 QVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVESFIT 303
+A +G V++ EL E + L V ++ +AF P ++ + I
Sbjct: 315 MLATKVGCNVSDTVELVECLQKKPYKEL--VDQDIQPARYHIAFGPVIDGDV------IP 366
Query: 304 KSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRMETSFPDFLQPDLQFEN 361
P + GEFL M G + EG ++ E I D + + F D +
Sbjct: 367 DDPQILMEQGEFLNYDIMLGVNQGEG-LKFVENIVDSDDGISASDFDFAVSNFVDNLYGY 425
Query: 362 AEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXXXXXXXXXXXXXXPVY 419
EG+ + E IK Y + + + L+ D V P Y
Sbjct: 426 PEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQ-WVAPAVATADLHSNFGSPTY 484
Query: 420 LYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSDDNIPLLDLTIGDILV 472
Y F + + P D AAH +E+ Y+ E N D+ + +++
Sbjct: 485 FYAFYHHCQTDQV---PAWAD-AAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 540
Query: 473 ERWTNFAKTGAP 484
WTNFAKTG P
Sbjct: 541 TYWTNFAKTGDP 552
>AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein.
Length = 826
Score = 139 bits (336), Expect = 3e-32
Identities = 132/492 (26%), Positives = 204/492 (41%), Gaps = 61/492 (12%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVG---------- 89
G F G+PYA +G RF+ P P + A + C + + G
Sbjct: 78 GPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVW 137
Query: 90 ------------YEGTEDCLVVDVLTPN----LDAAAQLPVMVWVKGKEFDSEYNQDFSF 133
+ +EDCL +++ P D+ PVMV++ G + +
Sbjct: 138 FTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDG 197
Query: 134 RNFVQK-DVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDD 192
+V+V+++N+R +LGFL G + A GN GL D+I L+W ENI FGG+P
Sbjct: 198 SVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLR 257
Query: 193 VTLFGHGSGAAAVDLVTLSPLA---------NGLVHKAIAQSGNAFAPWAVTRDNLNYAI 243
+T+FG G+G + V+L+TLS + GL +AIAQSG A + WAV+ YA
Sbjct: 258 ITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYAR 317
Query: 244 QVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVESFIT 303
+A +G V++ EL E + L V ++ +AF P ++ + I
Sbjct: 318 MLATKVGCNVSDTVELVECLQKKPYKEL--VDQDIQPARYHIAFGPVIDGDV------IP 369
Query: 304 KSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRMETSFPDFLQPDLQFEN 361
P + GEFL M G + EG ++ E I D + + F D +
Sbjct: 370 DDPQILMEQGEFLNYDIMLGVNQGEG-LKFVENIVDSDDGISASDFDFAVSNFVDNLYGY 428
Query: 362 AEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXXXXXXXXXXXXXXPVY 419
EG+ + E IK Y + + + L+ D V P Y
Sbjct: 429 PEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQ-WVAPAVATADLHSNFGSPTY 487
Query: 420 LYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSDDNIPLLDLTIGDILV 472
Y F + + P D AAH +E+ Y+ E N D+ + +++
Sbjct: 488 FYAFYHHCQTDQV---PAWAD-AAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 543
Query: 473 ERWTNFAKTGAP 484
WTNFAKTG P
Sbjct: 544 TYWTNFAKTGDP 555
>BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein.
Length = 568
Score = 138 bits (333), Expect = 7e-32
Identities = 147/533 (27%), Positives = 230/533 (43%), Gaps = 53/533 (9%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAV----LGSHAHDGEYFTFYGIPYADSTSGPHRF 60
V L L A+ +G + P V+ G V +G D F GIP+A GP RF
Sbjct: 16 VCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRF 75
Query: 61 KAPSSPPKFEGAFVANRRDVKCVRPLGVG-------------YEGTEDCLVVDVLTP-NL 106
AP +EG A+ C++ + + +EDCLV++V +P +
Sbjct: 76 SAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEV 135
Query: 107 DAAAQLPVMVWVKGKEFDSEYNQDFSFRNF-VQKDVVVVSINFRESILGFLCLGTEVAPG 165
A + PVMVWV G + + DVVVV++ +R +LGF G E APG
Sbjct: 136 PAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPG 195
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N G D++A L+WV+ENIA FGG+ + VT+FG +G + + + LSP+A GL H+AI QS
Sbjct: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G P + A ++A L ++ E+ + + L+ + +L T
Sbjct: 256 GVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNT---- 310
Query: 286 AFAPCLEREALSVESFI-TKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIEHDW--L 342
P L+V+ + KSP + + + F +PF+ G +E + I W L
Sbjct: 311 -IYP------LTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHE----FSWLIPRGWGLL 359
Query: 343 QRME-TSFPDFLQPDLQ-FENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMIL 400
ME S D L + + + + D Y + + + + + GD I
Sbjct: 360 DTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFIN 419
Query: 401 VXXXXXXXXXXXXXXXPVYLYQFSY-SGSLGKPFVGPIQVDAAAHSEELAYMF------Y 453
V PV+ Y+F + S K + P V A H E A++F
Sbjct: 420 V-PTVSFSRYLRDSGSPVFFYEFQHRPSSFAK--IKPAWV-KADHGAEGAFVFGGPFLMD 475
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
E S + + ++ +WT+FA+TG P S+ + W F + YL I
Sbjct: 476 ESSRLEATEEEKQLSLTMMAQWTHFARTGDPNSK-ALPPWPQF-NQAEQYLEI 526
>AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HNL3
protein.
Length = 828
Score = 137 bits (331), Expect = 1e-31
Identities = 113/391 (28%), Positives = 178/391 (45%), Gaps = 29/391 (7%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 176 DSGAK-PVMVYIHGGSYMEGTGNMIDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKG 234
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 235 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 294
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 295 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 352
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 353 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 405
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ + D + EG+ + E IK Y + + + ++ D V
Sbjct: 406 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ-WV 464
Query: 402 XXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF-------Y 453
P Y Y F + SL KP AAH +E+ Y+F
Sbjct: 465 EPSVVTADLHARYGSPTYFYAFYHHCQSLMKP-----AWSDAAHGDEVPYVFGVPMVGPT 519
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ N D+ + +++ WTNFAKTG P
Sbjct: 520 DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 550
>BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein.
Length = 828
Score = 136 bits (330), Expect = 2e-31
Identities = 113/391 (28%), Positives = 178/391 (45%), Gaps = 29/391 (7%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 176 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 234
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 235 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 294
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 295 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 352
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 353 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 405
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ + D + EG+ + E IK Y + + + ++ D V
Sbjct: 406 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ-WV 464
Query: 402 XXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF-------Y 453
P Y Y F + SL KP AAH +E+ Y+F
Sbjct: 465 EPSVVTADLHARYGSPTYFYAFYHHCQSLMKP-----AWSDAAHGDEVPYVFGVPMVGPT 519
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ N D+ + +++ WTNFAKTG P
Sbjct: 520 DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 550
>AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform
protein.
Length = 828
Score = 136 bits (330), Expect = 2e-31
Identities = 113/391 (28%), Positives = 178/391 (45%), Gaps = 29/391 (7%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 176 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 234
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 235 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 294
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 295 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 352
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 353 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 405
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ + D + EG+ + E IK Y + + + ++ D V
Sbjct: 406 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ-WV 464
Query: 402 XXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF-------Y 453
P Y Y F + SL KP AAH +E+ Y+F
Sbjct: 465 EPSVVTADLHARYGSPTYFYAFYHHCQSLMKP-----AWSDAAHGDEVPYVFGVPMVGPT 519
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ N D+ + +++ WTNFAKTG P
Sbjct: 520 DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 550
>AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform
protein.
Length = 848
Score = 136 bits (330), Expect = 2e-31
Identities = 113/391 (28%), Positives = 178/391 (45%), Gaps = 29/391 (7%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 196 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 254
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 255 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 314
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 315 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 372
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 373 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 425
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ + D + EG+ + E IK Y + + + ++ D V
Sbjct: 426 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ-WV 484
Query: 402 XXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF-------Y 453
P Y Y F + SL KP AAH +E+ Y+F
Sbjct: 485 EPSVVTADLHARYGSPTYFYAFYHHCQSLMKP-----AWSDAAHGDEVPYVFGVPMVGPT 539
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ N D+ + +++ WTNFAKTG P
Sbjct: 540 DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 570
>AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein.
Length = 682
Score = 136 bits (330), Expect = 2e-31
Identities = 113/391 (28%), Positives = 178/391 (45%), Gaps = 29/391 (7%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 30 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 88
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 89 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 148
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 149 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 206
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 207 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 259
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ + D + EG+ + E IK Y + + + ++ D V
Sbjct: 260 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQ-WV 318
Query: 402 XXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF-------Y 453
P Y Y F + SL KP AAH +E+ Y+F
Sbjct: 319 EPSVVTADLHARYGSPTYFYAFYHHCQSLMKP-----AWSDAAHGDEVPYVFGVPMVGPT 373
Query: 454 EKSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ N D+ + +++ WTNFAKTG P
Sbjct: 374 DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP 404
>AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase
hBr2 protein.
Length = 565
Score = 136 bits (330), Expect = 2e-31
Identities = 138/515 (26%), Positives = 217/515 (42%), Gaps = 42/515 (8%)
Query: 23 PIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFKAP-------------SS 65
P+V+ QG VLG + +G F G+P+A GP RF P S
Sbjct: 24 PVVDTVQGKVLGKYVSLEGFAQPVAVFLGVPFAKPPLGPLRFAPPQAAEPWNFVKNTTSY 83
Query: 66 PPKFEGAFVANR--RDVKCVRPLGVGYEGTEDCLVVDVLTP-NLDAAAQLPVMVWVKGKE 122
PP V + ++ R + + +EDCL +++ TP +L ++LPVMVW+ G
Sbjct: 84 PPMCSQDAVGGQVLSELFTNRKDNIPLKFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGG 143
Query: 123 FDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKE 181
+ ++VVVV+I +R I GF G E GN G D +A L+WV+E
Sbjct: 144 LVVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHGRGNWGHLDQLAALRWVQE 203
Query: 182 NIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNY 241
NIA+FGGNP VT+FG +G +V ++ LSPLA L H+AI++SG A V +D +
Sbjct: 204 NIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTAALVKKDMKDT 263
Query: 242 AIQVAEALGHIVTNIQELSEIFTRTSVAALMAV-----INELDLTDNSLAFAPCLEREAL 296
A Q+A G T L + + L+ V LDL + P L
Sbjct: 264 AQQIAVFAGCKSTTSAVLVHCLRQKTEDELLEVSLKLKFFTLDLLGDPRESYPFLPTVVD 323
Query: 297 SVESFITKSPYQTILDGEFLQIPFMTGFVENEG----TIRATEAIEHDWLQRMETSFPDF 352
V + K P + + + +F +P++ G + E + + D L + S
Sbjct: 324 GV--LLPKMPQEILAEKKFNSVPYIIGINKQEFGWLLPMMMGYPLSEDKLDQKTAS--SL 379
Query: 353 LQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXXXXXXXXX 412
L N E K ++ + + +L GD + V
Sbjct: 380 LWKSYPIANIPEELTPLASEKYLGGTDDPVKKKAL--FLDMLGDVVFGV-PSVTVARHHR 436
Query: 413 XXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK-SDDNIPLLDLTIGDIL 471
P Y+Y+F Y S + P Q H +EL +F ++ + ++
Sbjct: 437 DAGAPTYMYEFQYHPSFSSD-MKP-QTVVGDHGDELFSVFGAPFLKGGASEEEIRLSKMM 494
Query: 472 VERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
++ W NFA++G P+ + W P + YL+I
Sbjct: 495 MKLWANFARSGNPMGKGCS-SW-PAYDQKEGYLQI 527
>BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein.
Length = 518
Score = 136 bits (329), Expect = 2e-31
Identities = 105/359 (29%), Positives = 161/359 (44%), Gaps = 36/359 (10%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGY-------------- 90
+ G+PYA G RF P PP + G A C + +
Sbjct: 69 YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD 128
Query: 91 -------EGTEDCLVVDVLTPNLDA---AAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQK 139
E EDCL ++V P D + PVMV++ G + + N
Sbjct: 129 IVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYG 188
Query: 140 DVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHG 199
+V+V+++N+R +LGFL G + A GN GL D I L+WV ENIA FGG+P +T+FG G
Sbjct: 189 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 248
Query: 200 SGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQEL 259
GA+ V L+TLS + GL +AI QSG+A + WAV + Y +A+ +G V + ++
Sbjct: 249 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 308
Query: 260 SEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIP 319
+ + S L V ++ +AF P ++ + I P + GEFL
Sbjct: 309 VDCLRQKSAKEL--VEQDIQPARYHVAFGPVIDGDV------IPDDPEILMEQGEFLNYD 360
Query: 320 FMTGFVENEGTIRATEAI--EHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFY 376
M G + EG ++ E + D + + + D + EG+ + E IK Y
Sbjct: 361 VMLGVNQGEG-LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMY 418
>AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo
protein.
Length = 571
Score = 136 bits (328), Expect = 3e-31
Identities = 144/537 (26%), Positives = 231/537 (43%), Gaps = 58/537 (10%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAV----LGSHAHDGEYFTFYGIPYADSTSGPHRF 60
V L L A+ +G + P V+ G V +G D F GIP+A GP RF
Sbjct: 16 VCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRF 75
Query: 61 KAPSSPPKFEGAFVANRRDVKCVRPLGVG-------------YEGTEDCLVVDVLTP-NL 106
AP +EG A+ C++ + + +EDCLV++V +P +
Sbjct: 76 SAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEV 135
Query: 107 DAAAQLPVMVWVKGKEFDSEYNQDFSFRNF-VQKDVVVVSINFRESILGFLCLGTEVAPG 165
A + PVMVWV G + + DVVVV++ +R +LGF G E APG
Sbjct: 136 PAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPG 195
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N G D++A L+WV+ENIA FGG+ + VT+FG +G + + + LSP+A GL H+AI QS
Sbjct: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G P + A ++A L ++ E+ + + L+ + +L T
Sbjct: 256 GVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNT---- 310
Query: 286 AFAPCLEREALSVESFI-TKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIEHDW--L 342
P L+V+ + KSP + + + F +PF+ G +E + I W L
Sbjct: 311 -IYP------LTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHE----FSWLIPRGWGLL 359
Query: 343 QRME-TSFPDFLQPDLQ-FENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMIL 400
ME S D L + + + + D Y + + + + + GD I
Sbjct: 360 DTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFIN 419
Query: 401 VXXXXXXXXXXXXXXXPVYLYQFSY-SGSLGKPFVGPIQVDAAAHS----------EELA 449
V PV+ Y+F + S K ++ D A +E +
Sbjct: 420 V-PTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESS 478
Query: 450 YMFYEKSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + ++ + L LT ++ +WT+FA+TG P S+ + W F + YL I
Sbjct: 479 RLAFPEATEEEKQLSLT----MMAQWTHFARTGDPNSK-ALPPWPQF-NQAEQYLEI 529
>M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 135 bits (326), Expect = 5e-31
Identities = 106/315 (33%), Positives = 154/315 (48%), Gaps = 34/315 (10%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGYEG------- 92
G F GIPYA G RFK P S K+ + A + C + + + G
Sbjct: 51 GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMW 110
Query: 93 ------TEDCLVVDVLTPNLDAAAQLPVMVWVKGKEFD----SEYNQDFSFRNFVQKDVV 142
+EDCL ++V P V++W+ G F S + D F V++ V+
Sbjct: 111 NPNTDLSEDCLYLNVWIP-APKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVER-VI 168
Query: 143 VVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSG 201
VVS+N+R LGFL L G APGN GL D L+WV++NIA FGGNP VTLFG +G
Sbjct: 169 VVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAG 228
Query: 202 AAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTR--DNLNYAIQVAEALGHIVTNIQEL 259
AA+V L LSP ++ L +AI QSG+ APWAVT + N + +A+ G N E+
Sbjct: 229 AASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEI 288
Query: 260 SEIFTRTSVAALMAVINELDL----TDNSLAFAPCLEREALSVESFITKSPYQTILDGEF 315
+ ++ +NE + T S+ F P ++ + F+T P + G+F
Sbjct: 289 IKCLRNKDPQEIL--LNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQF 340
Query: 316 LQIPFMTGFVENEGT 330
+ + G ++EGT
Sbjct: 341 KKTQILVGVNKDEGT 355
Score = 33.1 bits (72), Expect = 3.2
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 444 HSEELAYMFYEKSD--DNIPLLDLTIGDILVERWTNFAKTGAP-VSETSQVVWRPFTTEN 500
H E+ ++F + DN + + +V+RW NFAK G P ++ + W F +
Sbjct: 466 HGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTE 525
Query: 501 NHYLRILDDS 510
YL + +S
Sbjct: 526 QKYLTLNTES 535
>M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 135 bits (326), Expect = 5e-31
Identities = 106/315 (33%), Positives = 154/315 (48%), Gaps = 34/315 (10%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGYEG------- 92
G F GIPYA G RFK P S K+ + A + C + + + G
Sbjct: 51 GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMW 110
Query: 93 ------TEDCLVVDVLTPNLDAAAQLPVMVWVKGKEFD----SEYNQDFSFRNFVQKDVV 142
+EDCL ++V P V++W+ G F S + D F V++ V+
Sbjct: 111 NPNTDLSEDCLYLNVWIP-APKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVER-VI 168
Query: 143 VVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSG 201
VVS+N+R LGFL L G APGN GL D L+WV++NIA FGGNP VTLFG +G
Sbjct: 169 VVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAG 228
Query: 202 AAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTR--DNLNYAIQVAEALGHIVTNIQEL 259
AA+V L LSP ++ L +AI QSG+ APWAVT + N + +A+ G N E+
Sbjct: 229 AASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEI 288
Query: 260 SEIFTRTSVAALMAVINELDL----TDNSLAFAPCLEREALSVESFITKSPYQTILDGEF 315
+ ++ +NE + T S+ F P ++ + F+T P + G+F
Sbjct: 289 IKCLRNKDPQEIL--LNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQF 340
Query: 316 LQIPFMTGFVENEGT 330
+ + G ++EGT
Sbjct: 341 KKTQILVGVNKDEGT 355
Score = 33.1 bits (72), Expect = 3.2
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 444 HSEELAYMFYEKSD--DNIPLLDLTIGDILVERWTNFAKTGAP-VSETSQVVWRPFTTEN 500
H E+ ++F + DN + + +V+RW NFAK G P ++ + W F +
Sbjct: 466 HGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTE 525
Query: 501 NHYLRILDDS 510
YL + +S
Sbjct: 526 QKYLTLNTES 535
>M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 135 bits (326), Expect = 5e-31
Identities = 106/315 (33%), Positives = 154/315 (48%), Gaps = 34/315 (10%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGYEG------- 92
G F GIPYA G RFK P S K+ + A + C + + + G
Sbjct: 51 GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMW 110
Query: 93 ------TEDCLVVDVLTPNLDAAAQLPVMVWVKGKEFD----SEYNQDFSFRNFVQKDVV 142
+EDCL ++V P V++W+ G F S + D F V++ V+
Sbjct: 111 NPNTDLSEDCLYLNVWIP-APKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVER-VI 168
Query: 143 VVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSG 201
VVS+N+R LGFL L G APGN GL D L+WV++NIA FGGNP VTLFG +G
Sbjct: 169 VVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAG 228
Query: 202 AAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTR--DNLNYAIQVAEALGHIVTNIQEL 259
AA+V L LSP ++ L +AI QSG+ APWAVT + N + +A+ G N E+
Sbjct: 229 AASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEI 288
Query: 260 SEIFTRTSVAALMAVINELDL----TDNSLAFAPCLEREALSVESFITKSPYQTILDGEF 315
+ ++ +NE + T S+ F P ++ + F+T P + G+F
Sbjct: 289 IKCLRNKDPQEIL--LNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQF 340
Query: 316 LQIPFMTGFVENEGT 330
+ + G ++EGT
Sbjct: 341 KKTQILVGVNKDEGT 355
Score = 33.1 bits (72), Expect = 3.2
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 444 HSEELAYMFYEKSD--DNIPLLDLTIGDILVERWTNFAKTGAP-VSETSQVVWRPFTTEN 500
H E+ ++F + DN + + +V+RW NFAK G P ++ + W F +
Sbjct: 466 HGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTE 525
Query: 501 NHYLRILDDS 510
YL + +S
Sbjct: 526 QKYLTLNTES 535
>BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 135 bits (326), Expect = 5e-31
Identities = 106/315 (33%), Positives = 154/315 (48%), Gaps = 34/315 (10%)
Query: 40 GEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGYEG------- 92
G F GIPYA G RFK P S K+ + A + C + + + G
Sbjct: 51 GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMW 110
Query: 93 ------TEDCLVVDVLTPNLDAAAQLPVMVWVKGKEFD----SEYNQDFSFRNFVQKDVV 142
+EDCL ++V P V++W+ G F S + D F V++ V+
Sbjct: 111 NPNTDLSEDCLYLNVWIP-APKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVER-VI 168
Query: 143 VVSINFRESILGFLCL-GTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSG 201
VVS+N+R LGFL L G APGN GL D L+WV++NIA FGGNP VTLFG +G
Sbjct: 169 VVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAG 228
Query: 202 AAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTR--DNLNYAIQVAEALGHIVTNIQEL 259
AA+V L LSP ++ L +AI QSG+ APWAVT + N + +A+ G N E+
Sbjct: 229 AASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEI 288
Query: 260 SEIFTRTSVAALMAVINELDL----TDNSLAFAPCLEREALSVESFITKSPYQTILDGEF 315
+ ++ +NE + T S+ F P ++ + F+T P + G+F
Sbjct: 289 IKCLRNKDPQEIL--LNEAFVVPYGTPLSVNFGPTVDGD------FLTDMPDILLELGQF 340
Query: 316 LQIPFMTGFVENEGT 330
+ + G ++EGT
Sbjct: 341 KKTQILVGVNKDEGT 355
Score = 33.1 bits (72), Expect = 3.2
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 444 HSEELAYMFYEKSD--DNIPLLDLTIGDILVERWTNFAKTGAP-VSETSQVVWRPFTTEN 500
H E+ ++F + DN + + +V+RW NFAK G P ++ + W F +
Sbjct: 466 HGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTE 525
Query: 501 NHYLRILDDS 510
YL + +S
Sbjct: 526 QKYLTLNTES 535
>AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein.
Length = 679
Score = 135 bits (326), Expect = 5e-31
Identities = 109/384 (28%), Positives = 172/384 (44%), Gaps = 26/384 (6%)
Query: 113 PVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKD 171
PVMV++ G + + N +V+V++IN+R ILGFL G + A GN GL D
Sbjct: 30 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 89
Query: 172 IIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAP 231
I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QSG A +
Sbjct: 90 QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 149
Query: 232 WAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAPCL 291
WAV Y +A+ +G + + ++ E + L + + +AF P +
Sbjct: 150 WAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKEL--IQQTITPATYHIAFGPVI 207
Query: 292 EREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQRMETSF 349
+ + I P + GEFL M G + EG ++ + I D + + F
Sbjct: 208 DGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVTPNDFDF 260
Query: 350 PDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILVXXXXXX 407
D + EG+ + E IK Y + ++ + ++ D V
Sbjct: 261 SVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQ-WVAPAVAT 319
Query: 408 XXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YEKSDDNI 460
P Y Y F + + + P D +AH +E+ Y+F E N
Sbjct: 320 ADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTELFSCNF 375
Query: 461 PLLDLTIGDILVERWTNFAKTGAP 484
D+ + +++ WTNFAKTG P
Sbjct: 376 SKNDVMLSAVVMTYWTNFAKTGDP 399
>AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein.
Length = 816
Score = 134 bits (323), Expect = 1e-30
Identities = 109/390 (27%), Positives = 175/390 (44%), Gaps = 27/390 (6%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D ++ PVMV++ G + + N +V+V++IN+R ILGFL G + A G
Sbjct: 162 DQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKG 221
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+W++EN+ FGG+P VT+FG G+GA+ V L+TLS + GL KAI QS
Sbjct: 222 NYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQS 281
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G A + WAV Y +A+ +G + + ++ E + L + + +
Sbjct: 282 GTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL--IQQTITPATYHI 339
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ + I D +
Sbjct: 340 AFGPVIDGDV------IPDDPQILMEQGEFLNYDIMLGVNQGEG-LKFVDGIVDNEDGVT 392
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGDTMILV 401
+ F D + EG+ + E IK Y + ++ + ++ D +
Sbjct: 393 PNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWV- 451
Query: 402 XXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMF-------YE 454
P Y Y F + + + P D +AH +E+ Y+F E
Sbjct: 452 -APAVAADLHAQYGSPTYFYAFYHH---CQSEMKPSWAD-SAHGDEVPYVFGIPMIGPTE 506
Query: 455 KSDDNIPLLDLTIGDILVERWTNFAKTGAP 484
N D+ + +++ WTNFAKTG P
Sbjct: 507 LFSCNFSKNDVMLSAVVMTYWTNFAKTGDP 536
>AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase
hBr3 protein.
Length = 567
Score = 126 bits (305), Expect = 2e-28
Identities = 102/333 (30%), Positives = 157/333 (47%), Gaps = 30/333 (9%)
Query: 23 PIVNIGQGAVLGSHAHDGEYFT-----FYGIPYADSTSGPHRFKAP-------------S 64
P+VN +G VLG + + E FT F G+P+A G RF P S
Sbjct: 24 PVVNTVKGKVLGKYVNL-EGFTQPVAFFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTS 82
Query: 65 SPPKFEGAFVANR--RDVKCVRPLGVGYEGTEDCLVVDVLTP-NLDAAAQLPVMVWVKGK 121
PP V + ++ R + + +EDCL +++ TP +L ++LPVMVW+ G
Sbjct: 83 YPPMCSQDAVGWQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGG 142
Query: 122 EFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVK 180
+ ++VVVV+I +R I GF G E + GN G D +A L+WV+
Sbjct: 143 GLVVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 181 ENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLN 240
+NIA+FGGNP VT+FG +G +V ++ LSPLA L H+AI++SG + +T D
Sbjct: 203 DNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKP 262
Query: 241 YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAV-----INELDLTDNSLAFAPCLEREA 295
A VA G T + + + L+ + +LDL N P L
Sbjct: 263 IAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVI 322
Query: 296 LSVESFITKSPYQTILDGEFLQIPFMTGFVENE 328
V + K+P + + + F +P++ G + E
Sbjct: 323 DGV--VLPKAPEEILAEKSFSTVPYIVGINKQE 353
>AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HNL3s
protein.
Length = 558
Score = 126 bits (304), Expect = 2e-28
Identities = 86/273 (31%), Positives = 136/273 (49%), Gaps = 13/273 (4%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 196 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 254
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 255 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 314
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 315 GSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 372
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI--EHDWLQ 343
AF P ++ + I P + GEFL M G + EG ++ E + D +
Sbjct: 373 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG-LKFVEGVVDPEDGVS 425
Query: 344 RMETSFPDFLQPDLQFENAEGESAIAEEIKDFY 376
+ + D + EG+ + E IK Y
Sbjct: 426 GTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMY 458
>M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 133/513 (25%), Positives = 213/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 132/514 (25%), Positives = 214/514 (41%), Gaps = 38/514 (7%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRF 60
++L L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 6 LVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 61 KAPSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLT 103
P P +FV N +D K + L + + +EDCL +++ T
Sbjct: 66 TPPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 123
Query: 104 P-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTE 161
P +L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 124 PADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDE 183
Query: 162 VAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKA 221
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+A
Sbjct: 184 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRA 243
Query: 222 IAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDL 280
I++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 281 TDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEA 336
L P + L + K+P + + F +P+M G + E G + +
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 363
Query: 337 IEHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYH 394
+ + Q + + L E + E + Y ++ + +L
Sbjct: 364 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLI 421
Query: 395 GDTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYE 454
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 422 ADVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGA 478
Query: 455 K-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 479 PFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 133/513 (25%), Positives = 213/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 133/513 (25%), Positives = 213/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 132/514 (25%), Positives = 214/514 (41%), Gaps = 38/514 (7%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRF 60
++L L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 6 LVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 61 KAPSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLT 103
P P +FV N +D K + L + + +EDCL +++ T
Sbjct: 66 TPPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 123
Query: 104 P-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTE 161
P +L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 124 PADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDE 183
Query: 162 VAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKA 221
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+A
Sbjct: 184 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRA 243
Query: 222 IAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDL 280
I++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 281 TDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEA 336
L P + L + K+P + + F +P+M G + E G + +
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 363
Query: 337 IEHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYH 394
+ + Q + + L E + E + Y ++ + +L
Sbjct: 364 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLI 421
Query: 395 GDTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYE 454
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 422 ADVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGA 478
Query: 455 K-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 479 PFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 133/513 (25%), Positives = 213/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 132/514 (25%), Positives = 214/514 (41%), Gaps = 38/514 (7%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRF 60
++L L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 6 LVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 61 KAPSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLT 103
P P +FV N +D K + L + + +EDCL +++ T
Sbjct: 66 TPPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 123
Query: 104 P-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTE 161
P +L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 124 PADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDE 183
Query: 162 VAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKA 221
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+A
Sbjct: 184 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRA 243
Query: 222 IAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDL 280
I++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 281 TDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEA 336
L P + L + K+P + + F +P+M G + E G + +
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 363
Query: 337 IEHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYH 394
+ + Q + + L E + E + Y ++ + +L
Sbjct: 364 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLI 421
Query: 395 GDTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYE 454
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 422 ADVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGA 478
Query: 455 K-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 479 PFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 126 bits (303), Expect = 3e-28
Identities = 133/513 (25%), Positives = 213/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein.
Length = 568
Score = 125 bits (302), Expect = 4e-28
Identities = 132/518 (25%), Positives = 215/518 (41%), Gaps = 38/518 (7%)
Query: 1 MRLKVILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSG 56
+R ++ L A+ +G P+V+ G VLG +G F GIP+ G
Sbjct: 3 LRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLG 62
Query: 57 PHRFKAPSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVV 99
P RF P P +FV N +D K + L + + +EDCL +
Sbjct: 63 PLRFTPPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120
Query: 100 DVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLC 157
++ TP +L +LPVMVW+ G + ++VVVV+I +R I GF
Sbjct: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180
Query: 158 LGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGL 217
G E + GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L
Sbjct: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240
Query: 218 VHKAIAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVIN 276
H+AI++SG A V + ++ A Q+A G T + + + L+
Sbjct: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300
Query: 277 ELDLTDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIR 332
++ L P + L + K+P + + F +P+M G + E G +
Sbjct: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360
Query: 333 ATEAIEHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDY 390
+ + + Q + + L E + E + Y ++ + +
Sbjct: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLF 418
Query: 391 LSYHGDTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAY 450
L D M V P Y+Y+F Y S + P V H +EL
Sbjct: 419 LDLIADVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFS 475
Query: 451 MFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+F + ++ + ++++ W NFA+ G P E
Sbjct: 476 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 513
>BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein.
Length = 454
Score = 125 bits (301), Expect = 6e-28
Identities = 87/250 (34%), Positives = 122/250 (48%), Gaps = 16/250 (6%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP----LGVGYEGT------- 93
F G+P++ G RF P P ++G A C++ L Y T
Sbjct: 14 FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWL 73
Query: 94 ---EDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD-VVVVSINF 148
EDCL ++V P QLPVMVW G F + + ++ VV+V +
Sbjct: 74 RFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQH 133
Query: 149 RESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLV 208
R I GFL A GN GL D +A L+WV+ENIA FGG+P +VTLFG +GA ++ +
Sbjct: 134 RLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGL 193
Query: 209 TLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSV 268
+SPLA+GL H+AI+QSG A +T + L A +VA G + Q L S
Sbjct: 194 MMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSG 253
Query: 269 AALMAVINEL 278
+M V N++
Sbjct: 254 TKVMRVSNKM 263
>BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 566
Score = 125 bits (301), Expect = 6e-28
Identities = 137/524 (26%), Positives = 214/524 (40%), Gaps = 59/524 (11%)
Query: 5 VILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRF 60
++L L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 6 LVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 61 KAPSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLT 103
P P +FV N +D K + L + + +EDCL +++ T
Sbjct: 66 TPPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 123
Query: 104 P-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTE 161
P +L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 124 PADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDE 183
Query: 162 VAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKA 221
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+A
Sbjct: 184 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRA 243
Query: 222 IAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDL 280
I++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 281 TDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAI 337
L P + L + K+P + + F +P+M G +
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQ---------- 353
Query: 338 EHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDT 397
E WL M S+P + Q + S + + ELI E YL DT
Sbjct: 354 EFGWLIPMLMSYP---LSEGQLDQKTAMSLLWKSYPLVCIAKELIPEAT-EKYLGGTDDT 409
Query: 398 -------------MILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAH 444
++ P Y+Y+F Y S + P V H
Sbjct: 410 VKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDH 467
Query: 445 SEELAYMFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+EL +F + ++ + ++++ W NFA+ G P E
Sbjct: 468 GDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 511
>S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholesterol
acyltransferase protein.
Length = 568
Score = 124 bits (299), Expect = 1e-27
Identities = 129/496 (26%), Positives = 207/496 (41%), Gaps = 38/496 (7%)
Query: 23 PIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANR- 77
P+V+ G VLG +G F GIP+A GP RF P P +FV N
Sbjct: 25 PVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQ--PAEPWSFVKNAT 82
Query: 78 -------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP-NLDAAAQLPVMVWVKG 120
+D K + L + + +EDCL +++ TP +L +LPVMVW+ G
Sbjct: 83 SYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHG 142
Query: 121 KEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWV 179
+ ++VVVV+I +R I GF G E + GN G D +A L+WV
Sbjct: 143 GGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWV 202
Query: 180 KENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNL 239
++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI++SG A V + ++
Sbjct: 203 QDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDV 262
Query: 240 N-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSV 298
A Q+A G T + + + L+ ++ L P + L
Sbjct: 263 KPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGT 322
Query: 299 ---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAIEHDWL--QRMETSFPDF 352
+ K+P + + F +P+M G + E G + + + + Q + +
Sbjct: 323 VIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSL 382
Query: 353 LQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVXXXXXXXXXXX 412
L E + E + Y ++ + +L D M V
Sbjct: 383 LWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGV-PSVIVARNHR 439
Query: 413 XXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK-SDDNIPLLDLTIGDIL 471
P Y+Y+F Y S + P V H +EL +F + ++ + ++
Sbjct: 440 DAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAPFLKEGASEEEIRLSKMV 497
Query: 472 VERWTNFAKTGAPVSE 487
++ W NFA+ G P E
Sbjct: 498 MKFWANFARNGNPNGE 513
>BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein
protein.
Length = 351
Score = 124 bits (299), Expect = 1e-27
Identities = 77/224 (34%), Positives = 118/224 (52%), Gaps = 10/224 (4%)
Query: 107 DAAAQLPVMVWVKGKEF-DSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPG 165
D+ A+ PVMV++ G + + N +V+V+++N+R +LGFL G + A G
Sbjct: 59 DSGAK-PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKG 117
Query: 166 NAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQS 225
N GL D I L+WV ENIA FGG+P +T+FG G GA+ V L+TLS + GL +AI QS
Sbjct: 118 NYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQS 177
Query: 226 GNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSL 285
G+A + WAV + Y +A+ +G V + ++ + + S L V ++ +
Sbjct: 178 GSALSSWAVNYQPVEYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL--VEQDIQPARYHV 235
Query: 286 AFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEG 329
AF P ++ + I P + GEFL M G + EG
Sbjct: 236 AFGPVIDGDV------IPDDPEILMEQGEFLNYDIMLGVNQGEG 273
>AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester
hydrolase protein.
Length = 567
Score = 124 bits (299), Expect = 1e-27
Identities = 133/513 (25%), Positives = 212/513 (41%), Gaps = 38/513 (7%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP R
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRST 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N RD K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTRDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE-GTIRATEAI 337
L P + L + K+P + + F +P+M G + E G + + +
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLM 364
Query: 338 EHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHG 395
+ Q + + L E + E + Y ++ + +L
Sbjct: 365 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDTVKKKDLFLDLIA 422
Query: 396 DTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
D M V P Y+Y+F Y S + P V H +EL +F
Sbjct: 423 DVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHGDELFSVFGAP 479
Query: 456 -SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ ++ + ++++ W NFA+ G P E
Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 512
>AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase
hBr1 protein.
Length = 429
Score = 124 bits (299), Expect = 1e-27
Identities = 104/350 (29%), Positives = 158/350 (45%), Gaps = 29/350 (8%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+A GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENE 328
L P + L + K+P + + F +P+M G + E
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354
>BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein.
Length = 442
Score = 124 bits (298), Expect = 1e-27
Identities = 113/414 (27%), Positives = 182/414 (43%), Gaps = 35/414 (8%)
Query: 111 QLPVMVWVKGKEFDSEYNQDFSFRNFVQKD-VVVVSINFRESILGFLCLGTEVAPGNAGL 169
QLPVMVW G F + + ++ VV+V + R I GFL A GN GL
Sbjct: 13 QLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGL 72
Query: 170 KDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAF 229
D +A L+WV+ENIA FGG+P +VTLFG +GA ++ + +SPLA+GL H+AI+QSG A
Sbjct: 73 LDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTAL 132
Query: 230 APWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAP 289
+TR+ L A +VA G + Q L S +M V N++ + P
Sbjct: 133 FRLFITRNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDP 192
Query: 290 --CLEREALSVES-FITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIEHDWLQRME 346
+ + V+ I P + G+ +P++ G V N +E +WL
Sbjct: 193 EEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLG-VNN---------LEFNWLLPYI 242
Query: 347 TSFP---DFLQPDLQFENAEGESAIAEEIKDF--YFKNELISMFNIEDYLSYHGDTMILV 401
FP ++ + + + K+ E + N D+ M +V
Sbjct: 243 MKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIV 302
Query: 402 XXXXXXXXXXXX------XXXPVYLYQFSY--SGSLGKPFVGPIQVDAAAHSEELAYMFY 453
PVYLY+F + G + KP + D A H +E+ ++F
Sbjct: 303 QDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKP-----RTDGADHGDEMYFLFG 357
Query: 454 EKSDDNIPL-LDLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + + + +++ W NFA+TG P ++ + W P ++ YL++
Sbjct: 358 GPFATGLSMGKEKALSLQMMKYWANFARTGNP-NDGNLPCW-PRYNKDEKYLQL 409
>L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein.
Length = 566
Score = 123 bits (297), Expect = 2e-27
Identities = 137/523 (26%), Positives = 212/523 (40%), Gaps = 59/523 (11%)
Query: 6 ILPLLFFASISGEDFELPIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFK 61
IL L ++ G P+V+ G VLG +G F GIP+ GP RF
Sbjct: 7 ILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLGPLRFT 66
Query: 62 APSSPPKFEGAFVANR--------RDVKCVRPLG---------VGYEGTEDCLVVDVLTP 104
P P +FV N +D K + L + + +EDCL +++ TP
Sbjct: 67 PPQ--PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTP 124
Query: 105 -NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEV 162
+L +LPVMVW+ G + ++VVVV+I +R I GF G E
Sbjct: 125 ADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 184
Query: 163 APGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAI 222
+ GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI
Sbjct: 185 SRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 244
Query: 223 AQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLT 281
++SG A V + ++ A Q+A G T + + + L+ ++
Sbjct: 245 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 304
Query: 282 DNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIE 338
L P + L + K+P + + F +P+M G + E
Sbjct: 305 SLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQ----------E 354
Query: 339 HDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDT- 397
WL M S+P + Q + S + + ELI E YL DT
Sbjct: 355 FGWLIPMLMSYP---LSEGQLDQKTAMSLLWKSYPLVCIAKELIPEAT-EKYLGGTDDTV 410
Query: 398 ------------MILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAAHS 445
++ P Y+Y+F Y S + P V H
Sbjct: 411 KKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGDHG 468
Query: 446 EELAYMFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+EL +F + ++ + ++++ W NFA+ G P E
Sbjct: 469 DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 511
>AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo
protein.
Length = 545
Score = 122 bits (293), Expect = 5e-27
Identities = 73/188 (38%), Positives = 102/188 (54%), Gaps = 2/188 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKD-VVVVSINFRE 150
+EDCL ++V P QLPVMVW G F + + ++ VV+V + R
Sbjct: 217 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRL 276
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GFL A GN GL D +A L+WV+ENIA FGG+P +VTLFG +GA ++ + +
Sbjct: 277 GIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMM 336
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAA 270
SPLA+GL H+AI+QSG A +T + L A +VA G + Q L S
Sbjct: 337 SPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTK 396
Query: 271 LMAVINEL 278
+M V N++
Sbjct: 397 VMRVSNKM 404
>M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein.
Length = 507
Score = 120 bits (288), Expect = 2e-26
Identities = 105/405 (25%), Positives = 174/405 (42%), Gaps = 15/405 (3%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRE 150
+EDCL +++ TP +L +LPVMVW+ G + ++VVVV+I +R
Sbjct: 53 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 112
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF G E + GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ L
Sbjct: 113 GIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 172
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVA 269
SPLA L H+AI++SG A V + ++ A Q+A G T + + +
Sbjct: 173 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 232
Query: 270 ALMAVINELDLTDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVE 326
L+ ++ L P + L + K+P + + F +P+M G +
Sbjct: 233 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 292
Query: 327 NE-GTIRATEAIEHDWL--QRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELIS 383
E G + + + + Q + + L E + E + Y +
Sbjct: 293 QEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKE--LIPEATEKYLGGTDDT 350
Query: 384 MFNIEDYLSYHGDTMILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPFVGPIQVDAAA 443
+ + +L D M V P Y+Y+F Y S + P V
Sbjct: 351 VKKKDLFLDLIADVMFGV-PSVIVARNHRDAGAPTYMYEFQYRPSFSSD-MKPKTV-IGD 407
Query: 444 HSEELAYMFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
H +EL +F + ++ + ++++ W NFA+ G P E
Sbjct: 408 HGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 452
>AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-related
protein protein.
Length = 288
Score = 119 bits (287), Expect = 3e-26
Identities = 86/247 (34%), Positives = 123/247 (49%), Gaps = 26/247 (10%)
Query: 23 PIVNIGQGAVLGSHAH-DG---EYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVAN-- 76
P+V+ G VLG +G F GIP+A GP RF P P +FV N
Sbjct: 25 PVVDTVHGKVLGKFISLEGFAQPVAVFLGIPFAKPPLGPLRFTPPQ--PAEPWSFVKNAT 82
Query: 77 ----------RRDVKCVRPL------GVGYEGTEDCLVVDVLTP-NLDAAAQLPVMVWVK 119
RR + + L + + +EDCL +++ TP +L +LPVMVW+
Sbjct: 83 LYPPMFTQDPRRGGQLISELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIH 142
Query: 120 GKEFDSEYNQDFS-FRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKW 178
G + ++VVVV+I +R I GF G E +PGN G D +A L W
Sbjct: 143 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHW 202
Query: 179 VKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDN 238
V++NIA FGGNP VT+FG +G +V ++ LSPLA L H+AI++SG A V + +
Sbjct: 203 VQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 262
Query: 239 LNYAIQV 245
+ +V
Sbjct: 263 VKPLAEV 269
>X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage
serine-esterase 1 protein.
Length = 503
Score = 119 bits (286), Expect = 4e-26
Identities = 110/415 (26%), Positives = 174/415 (41%), Gaps = 36/415 (8%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRE 150
+EDCL +++ TP +L +LPVMVW+ G + ++VVVV+I +R
Sbjct: 50 SEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRL 109
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF G E + GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ L
Sbjct: 110 GIWGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVL 169
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVA 269
SPLA L H+AI++SG A V + ++ A Q+A G T + + +
Sbjct: 170 SPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEE 229
Query: 270 ALMAVINELDLTDNSLAFAPCLEREALSV---ESFITKSPYQTILDGEFLQIPFMTGFVE 326
L+ ++ L P + L + K+P + + F +P+M G +
Sbjct: 230 ELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINK 289
Query: 327 NEGTIRATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFN 386
E WL M S+P + Q + S + + ELI
Sbjct: 290 Q----------EFGWLIPMLMSYP---LSEGQLDQKTAMSLLWKSYPLVCIAKELIPEAT 336
Query: 387 IEDYLSYHGDT-------------MILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGKPF 433
E YL DT ++ P Y+Y+F Y S
Sbjct: 337 -EKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSD- 394
Query: 434 VGPIQVDAAAHSEELAYMFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAPVSE 487
+ P V H +EL +F + ++ + ++++ W NFA+ G P E
Sbjct: 395 MKPKTV-IGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGE 448
>BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHD 264
>BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7
protein.
Length = 525
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHD 264
>BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHD 264
>AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5
protein.
Length = 575
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHD 264
>AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 469
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 12 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 71
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 72 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 131
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 132 SPMAKGLFHKAIMESGVAIIPYLEAHD 158
>AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 525
Score = 119 bits (286), Expect = 4e-26
Identities = 60/147 (40%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Query: 93 TEDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQ-KDVVVVSINFRE 150
+EDCL +++ P + D ++LPV+VW G F + F +DV+VV + +R
Sbjct: 118 SEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
Query: 151 SILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTL 210
I GF + APGN KD +A L WV++NI FGG+P VT+FG +GA +V + L
Sbjct: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
Query: 211 SPLANGLVHKAIAQSGNAFAPWAVTRD 237
SP+A GL HKAI +SG A P+ D
Sbjct: 238 SPMAKGLFHKAIMESGVAIIPYLEAHD 264
>M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein.
Length = 454
Score = 115 bits (276), Expect = 6e-25
Identities = 112/414 (27%), Positives = 178/414 (42%), Gaps = 41/414 (9%)
Query: 94 EDCLVVDVLTP-NLDAAAQLPVMVWVKGKEFDSEYNQDFS-FRNFVQKDVVVVSINFRES 151
E CL +++ TP +L +LPVMVW+ G + ++VVVV+I +R
Sbjct: 1 EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLG 60
Query: 152 ILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLS 211
I GF G E + GN G D +A L+WV++NIA FGGNP VT+FG +G +V ++ LS
Sbjct: 61 IWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLS 120
Query: 212 PLANGLVHKAIAQSGNAFAPWAVTRDNLN-YAIQVAEALGHIVTNIQELSEIFTRTSVAA 270
PLA L H+AI++SG A V + ++ A Q+A G T + + +
Sbjct: 121 PLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAAMVHCLRQKTEEE 180
Query: 271 LMAVINELDLTDNSLAFAPCLEREALSVESFI-----TKSPYQTILDGEFLQIPFMTGFV 325
L+ L + ++ L +RE+ + + I K+P + + F +P+M G
Sbjct: 181 LLE--TTLKIGNSYLWTYRETQRESTLLGTVIDGMLLLKTPEELQRERNFHTVPYMVGIN 238
Query: 326 ENEGTIRATEAIEHDWLQRME-TSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISM 384
+ E WL M+ S+P + Q + S + I F ELI
Sbjct: 239 KQ----------EFGWLIPMQLMSYP---LSEGQLDQKTAMSLLGSPIPLFAIAKELIPE 285
Query: 385 FNIEDYLSYHGDT-------------MILVXXXXXXXXXXXXXXXPVYLYQFSYSGSLGK 431
E YL DT ++ P Y+Y+F Y S
Sbjct: 286 AT-EKYLGGTDDTVKKKDLILDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSS 344
Query: 432 PFVGPIQVDAAAHSEELAYMFYEK-SDDNIPLLDLTIGDILVERWTNFAKTGAP 484
+ P V H +EL +F + ++ + ++++ W NFA+ G P
Sbjct: 345 D-MKPKTV-IGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNP 396
>AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens
cDNA FLJ40219 fis, clone TESTI2021637, moderately
similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
3.1.1.1). ).
Length = 207
Score = 101 bits (241), Expect = 1e-20
Identities = 49/110 (44%), Positives = 69/110 (62%)
Query: 140 DVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHG 199
DVVVV++ +R +LGF G E APGN G D++A L+WV+ENIA FGG+ + VT+FG
Sbjct: 27 DVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGS 86
Query: 200 SGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEAL 249
+G + + + LSP+A GL H+AI QSG P + A ++A L
Sbjct: 87 AGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTL 136
>BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein.
Length = 151
Score = 98.7 bits (235), Expect = 6e-20
Identities = 48/107 (44%), Positives = 68/107 (63%)
Query: 139 KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGH 198
++VVVV+I +R I GF G E +PGN G D +A L WV++NIA FGGNP VT+FG
Sbjct: 26 ENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAALHWVQDNIASFGGNPGSVTIFGG 85
Query: 199 GSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQV 245
+G +V ++ LSPLA L H+AI++SG A V + ++ +V
Sbjct: 86 SAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEV 132
>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
Length = 1124
Score = 92.7 bits (220), Expect = 4e-18
Identities = 91/363 (25%), Positives = 160/363 (44%), Gaps = 28/363 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP---LGVGYEGTEDCLVVDV 101
F G+PYA RF+AP P + G++ A++ C +P +EDCL ++V
Sbjct: 584 FLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNV 642
Query: 102 LTPNLDAAAQLPVMVWVKGKEFDSEYNQ-----DFSFRNFVQKDVVVVSINFRESILGFL 156
P + A V+V+ D E ++ D SF V +++VV+ ++R + GFL
Sbjct: 643 FIPQ-NVAPNASVLVFFHNT-MDREESEGWPAIDGSFLAAVG-NLIVVTASYRVGVFGFL 699
Query: 157 CLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGA--AAVDLVTLSPLA 214
G+ GN GL D +A L WV+ +I FGG+P V+L GA A++ L+T
Sbjct: 700 SSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATN 759
Query: 215 NGLVHKAIAQSGNAFAPWAVTRDN--LNYAIQVAEALGHIVTNIQELSEIFTRTSVAALM 272
+ L +A+ G+A +P AV AI +A+ + +++ QE+ + L
Sbjct: 760 SQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLN 819
Query: 273 AVINELDLTDNSLAF-APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+L + P ++ F+ + P + + ++++ + G +++G I
Sbjct: 820 DAQTKLLAVSGPFHYWGPVIDGH------FLREPPARALKRSLWVEVDLLIGSSQDDGLI 873
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFE-NAEGESAIAEEIKDFYFKNELISMFNIEDY 390
+A++ R TS LQ E A E +Y+ E + +DY
Sbjct: 874 NRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLE----HSTDDY 929
Query: 391 LSY 393
S+
Sbjct: 930 ASF 932
>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
variant protein.
Length = 1574
Score = 91.5 bits (217), Expect = 8e-18
Identities = 90/363 (24%), Positives = 161/363 (44%), Gaps = 28/363 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP---LGVGYEGTEDCLVVDV 101
F G+PYA RF+AP P + G++ A++ C +P +EDCL ++V
Sbjct: 1034 FLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNV 1092
Query: 102 LTPNLDAAAQLPVMVWVKGKEFDSEYNQ-----DFSFRNFVQKDVVVVSINFRESILGFL 156
P + A V+V+ D E ++ D SF V +++VV+ ++R + GFL
Sbjct: 1093 FIPQ-NVAPNASVLVFFHNT-MDREESEGWPAIDGSFLAAVG-NLIVVTASYRVGVFGFL 1149
Query: 157 CLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGA--AAVDLVTLSPLA 214
G+ GN GL D +A L WV+ +I FGG+P V+L GA A++ L+T
Sbjct: 1150 SSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATN 1209
Query: 215 NGLVHKAIAQSGNAFAPWAVTRDN--LNYAIQVAEALGHIVTNIQELSEIFTRTSVAALM 272
+ L +A+ G+A +P AV AI +A+ + +++ QE+ + L
Sbjct: 1210 SQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLN 1269
Query: 273 AVINELDLTDNSLAF-APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+L + P ++ F+ + P + + ++++ + G +++G I
Sbjct: 1270 DAQTKLLAVSGPFHYWGPVIDGH------FLREPPARALKRSLWVEVDLLIGSSQDDGLI 1323
Query: 332 RATEAI-EHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDY 390
+A+ + + Q +S F Q E A E +Y+ E + +DY
Sbjct: 1324 NRAKAVKQFEESQGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLE----HSTDDY 1379
Query: 391 LSY 393
S+
Sbjct: 1380 ASF 1382
>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
Length = 2767
Score = 90.6 bits (215), Expect = 1e-17
Identities = 90/363 (24%), Positives = 159/363 (43%), Gaps = 28/363 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP---LGVGYEGTEDCLVVDV 101
F G+PYA F+AP P + G++ A++ C +P +EDCL ++V
Sbjct: 2227 FLGVPYAAPPLAERHFQAPE-PLNWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNV 2285
Query: 102 LTPNLDAAAQLPVMVWVKGKEFDSEYNQ-----DFSFRNFVQKDVVVVSINFRESILGFL 156
P + A V+V+ D E ++ D SF V +++VV+ ++R + GFL
Sbjct: 2286 FIPQ-NVAPNASVLVFFHNT-MDREESEGWPAIDGSFLAAVG-NLIVVTASYRVGVFGFL 2342
Query: 157 CLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGA--AAVDLVTLSPLA 214
G+ GN GL D +A L WV+ +I FGG+P V+L GA A++ L+T
Sbjct: 2343 SSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATN 2402
Query: 215 NGLVHKAIAQSGNAFAPWAVTRDN--LNYAIQVAEALGHIVTNIQELSEIFTRTSVAALM 272
+ L +A+ G+A +P AV AI +A+ + +++ QE+ + L
Sbjct: 2403 SQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLN 2462
Query: 273 AVINELDLTDNSLAF-APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+L + P ++ F+ + P + + ++++ + G +++G I
Sbjct: 2463 DAQTKLLAVSGPFHYWGPVIDGH------FLREPPARALKRSLWVEVDLLIGSSQDDGLI 2516
Query: 332 RATEAIEHDWLQRMETSFPDFLQPDLQFE-NAEGESAIAEEIKDFYFKNELISMFNIEDY 390
+A++ R TS LQ E A E +Y+ E + +DY
Sbjct: 2517 NRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLE----HSTDDY 2572
Query: 391 LSY 393
S+
Sbjct: 2573 ASF 2575
>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
Length = 2768
Score = 90.6 bits (215), Expect = 1e-17
Identities = 90/363 (24%), Positives = 160/363 (44%), Gaps = 28/363 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP---LGVGYEGTEDCLVVDV 101
F G+PYA RF+AP P + G++ A++ C +P +EDCL ++V
Sbjct: 2228 FLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNV 2286
Query: 102 LTPNLDAAAQLPVMVWVKGKEFDSEYNQ-----DFSFRNFVQKDVVVVSINFRESILGFL 156
P + A V+V+ D E ++ D SF V +++VV+ ++R + GFL
Sbjct: 2287 FIPQ-NVAPNASVLVFFHNT-MDREESEGWPAIDGSFLAAVG-NLIVVTASYRVGVFGFL 2343
Query: 157 CLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGA--AAVDLVTLSPLA 214
G+ GN GL D +A L WV+ +I FGG+P V+L GA A++ L+T
Sbjct: 2344 SSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATN 2403
Query: 215 NGLVHKAIAQSGNAFAPWAVTRDN--LNYAIQVAEALGHIVTNIQELSEIFTRTSVAALM 272
+ L +A+ G+A +P AV AI +A+ + +++ QE+ + L
Sbjct: 2404 SQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLN 2463
Query: 273 AVINELDLTDNSLAF-APCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTI 331
+L + P ++ F+ + P + + +++ + G +++G I
Sbjct: 2464 DAQTKLLAVSGPFHYWGPVIDGH------FLREPPARALKRSLXVEVDLLIGSSQDDGLI 2517
Query: 332 RATEAI-EHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDY 390
+A+ + + Q +S F Q E A E +Y+ E + +DY
Sbjct: 2518 NRAKAVKQFEESQGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLE----HSTDDY 2573
Query: 391 LSY 393
S+
Sbjct: 2574 ASF 2576
>AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens
cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
Length = 367
Score = 90.2 bits (214), Expect = 2e-17
Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 36/352 (10%)
Query: 173 IAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNA-FAP 231
+A L+WV+ENIA FGG+P +VTLFG +GA ++ + +SPLA+GL H+AI+QSG A F P
Sbjct: 1 MAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRP 60
Query: 232 WAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAP-- 289
+ +T + L A +VA G + Q L S +M V N++ + P
Sbjct: 61 F-ITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEE 119
Query: 290 CLEREALSVES-FITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIEHDWLQRMETS 348
+ + V+ I P + G+ +P++ G V N +E +WL
Sbjct: 120 IIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLG-VNN---------LEFNWLLPYIMK 169
Query: 349 FP---DFLQPDLQFENAEGESAIAEEIKDF--YFKNELISMFNIEDYLSYHGDTMILVXX 403
FP ++ + + + K+ E + N D+ M +V
Sbjct: 170 FPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQD 229
Query: 404 XXXXXXXXXX------XXXPVYLYQFSY--SGSLGKPFVGPIQVDAAAHSEELAYMFYEK 455
PVYLY+F + G + KP + D A H +E+ ++F
Sbjct: 230 ATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKP-----RTDGADHGDEMYFLFGGP 284
Query: 456 SDDNIPL-LDLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRI 506
+ + + + +++ W NFA+TG P ++ + W P ++ YL++
Sbjct: 285 FATGLSMGKEKALSLQMMKYWANFARTGNP-NDGNLPCW-PRYNKDEKYLQL 334
>BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for
IMAGE:40133565) protein.
Length = 422
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/200 (32%), Positives = 101/200 (50%), Gaps = 14/200 (7%)
Query: 45 FYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRP---LGVGYEGTEDCLVVDV 101
F G+PYA RF+AP P + G++ A++ C +P +EDCL ++V
Sbjct: 190 FLGVPYAAPPLAERRFQAPE-PLNWTGSWDASKPRASCWQPGTRTSTSPGVSEDCLYLNV 248
Query: 102 LTPNLDAAAQLPVMVWVKGKEFDSEYNQ-----DFSFRNFVQKDVVVVSINFRESILGFL 156
P + A V+V+ D E ++ D SF V +++VV+ ++R + GFL
Sbjct: 249 FIPQ-NVAPNASVLVFFHNT-MDREESEGWPAIDGSFLAAVG-NLIVVTASYRVGVFGFL 305
Query: 157 CLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGA--AAVDLVTLSPLA 214
G+ GN GL D +A L WV+ +I FGG+P V+L GA A++ L+T
Sbjct: 306 SSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATN 365
Query: 215 NGLVHKAIAQSGNAFAPWAV 234
+ L +A+ G+A +P AV
Sbjct: 366 SQLFRRAVLMGGSALSPAAV 385
>AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein.
Length = 550
Score = 56.0 bits (129), Expect = 4e-07
Identities = 76/312 (24%), Positives = 115/312 (36%), Gaps = 39/312 (12%)
Query: 220 KAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELD 279
KAIAQSG A + W+V L Y +A +G + E E R L V ++
Sbjct: 1 KAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL--VDQDVQ 58
Query: 280 LTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIE- 338
+AF P ++ + + P + GEFL + G + EG ++ E
Sbjct: 59 PARYHIAFGPVVDGDV------VPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAES 112
Query: 339 HDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFY--FKNELISMFNIEDYLSYHGD 396
D + F D + EG+ + E IK Y + + + L+ D
Sbjct: 113 EDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTD 172
Query: 397 TMILVXXXXXXXXXXXXXXXPVYLYQF-SYSGSLGKPFVGPIQVDAAAHSEELAYMF--- 452
V PVY Y F + + G+P + AAH +EL Y+F
Sbjct: 173 HQ-WVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRP-----EWADAAHGDELPYVFGVP 226
Query: 453 ----YEKSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQ--------------VVWR 494
+ N D+ + +++ WTNFAKTG P Q VVW
Sbjct: 227 MVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWS 286
Query: 495 PFTTENNHYLRI 506
F ++ YL I
Sbjct: 287 KFNSKEKQYLHI 298
>BC042923-1|AAH42923.1| 2541|Homo sapiens talin 1 protein.
Length = 2541
Score = 34.3 bits (75), Expect = 1.4
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 18/184 (9%)
Query: 134 RNFVQ--KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPD 191
R FVQ K+V + N ++I TE A + A L +N++ F NP+
Sbjct: 1523 RQFVQSAKEVANSTANLVKTIKALDGAFTE--ENRAQCRAATAPLLEAVDNLSAFASNPE 1580
Query: 192 DVTLFGHGS--GAAAVDLVTLSPL-----ANGLVHKAIAQSGNAFAP--WAVTRDNLNYA 242
++ S G AA++ + +S A GL+ A A + N P W+V ++
Sbjct: 1581 FSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLA---GHS 1637
Query: 243 IQVAEALGHIVTNIQELS--EIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVES 300
V++++ ++T++++ + ++ T++AAL + + +LD + RE +S E+
Sbjct: 1638 RTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA 1697
Query: 301 FITK 304
T+
Sbjct: 1698 LHTQ 1701
>AF178534-1|AAF27330.1| 2540|Homo sapiens talin protein.
Length = 2540
Score = 34.3 bits (75), Expect = 1.4
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 18/184 (9%)
Query: 134 RNFVQ--KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPD 191
R FVQ K+V + N ++I TE A + A L +N++ F NP+
Sbjct: 1523 RQFVQSAKEVANSTANLVKTIKALDGAFTE--ENRAQCRAATAPLLEAVDNLSAFASNPE 1580
Query: 192 DVTLFGHGS--GAAAVDLVTLSPL-----ANGLVHKAIAQSGNAFAP--WAVTRDNLNYA 242
++ S G AA++ + +S A GL+ A A + N P W+V ++
Sbjct: 1581 FSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLA---GHS 1637
Query: 243 IQVAEALGHIVTNIQELS--EIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVES 300
V++++ ++T++++ + ++ T++AAL + + +LD + RE +S E+
Sbjct: 1638 RTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA 1697
Query: 301 FITK 304
T+
Sbjct: 1698 LHTQ 1701
>AB028950-1|BAA82979.2| 2550|Homo sapiens KIAA1027 protein protein.
Length = 2550
Score = 34.3 bits (75), Expect = 1.4
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 18/184 (9%)
Query: 134 RNFVQ--KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPD 191
R FVQ K+V + N ++I TE A + A L +N++ F NP+
Sbjct: 1532 RQFVQSAKEVANSTANLVKTIKALDGAFTE--ENRAQCRAATAPLLEAVDNLSAFASNPE 1589
Query: 192 DVTLFGHGS--GAAAVDLVTLSPL-----ANGLVHKAIAQSGNAFAP--WAVTRDNLNYA 242
++ S G AA++ + +S A GL+ A A + N P W+V ++
Sbjct: 1590 FSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLA---GHS 1646
Query: 243 IQVAEALGHIVTNIQELS--EIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVES 300
V++++ ++T++++ + ++ T++AAL + + +LD + RE +S E+
Sbjct: 1647 RTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA 1706
Query: 301 FITK 304
T+
Sbjct: 1707 LHTQ 1710
>AF177198-1|AAF23322.1| 2541|Homo sapiens talin protein.
Length = 2541
Score = 33.5 bits (73), Expect = 2.4
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 18/184 (9%)
Query: 134 RNFVQ--KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPD 191
R FVQ K+V + N ++I TE A + A L +N++ F NP+
Sbjct: 1523 RQFVQSAKEVANSTANLVKTIKALDGPFTE--ENRAQCRAATAPLLEAVDNLSAFASNPE 1580
Query: 192 DVTLFGHGS--GAAAVDLVTLSPL-----ANGLVHKAIAQSGNAFAP--WAVTRDNLNYA 242
++ S G AA++ + +S A GL+ A A + N P W+V ++
Sbjct: 1581 FSSIPAQISPEGRAAMEPIVISAQTMLESAGGLIQTARALAVNPRDPPSWSVLA---GHS 1637
Query: 243 IQVAEALGHIVTNIQELS--EIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVES 300
V++++ ++T++++ + ++ T++AAL + + +LD + RE +S E+
Sbjct: 1638 RTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA 1697
Query: 301 FITK 304
T+
Sbjct: 1698 LHTE 1701
>AF078828-1|AAD13152.1| 2541|Homo sapiens talin protein.
Length = 2541
Score = 33.5 bits (73), Expect = 2.4
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 18/184 (9%)
Query: 134 RNFVQ--KDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPD 191
R FVQ K+V + N ++I TE A + A L +N++ F NP+
Sbjct: 1523 RQFVQSAKEVANSTANLVKTIKALDGPFTE--ENRAQCRAATAPLLEAVDNLSAFASNPE 1580
Query: 192 DVTLFGHGS--GAAAVDLVTLSPL-----ANGLVHKAIAQSGNAFAP--WAVTRDNLNYA 242
++ S G AA++ + +S A GL+ A A + N P W+V ++
Sbjct: 1581 FSSIPAQISPEGRAAMEPIVISAQTMLESAGGLIQTARALAVNPRDPPSWSVLA---GHS 1637
Query: 243 IQVAEALGHIVTNIQELS--EIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVES 300
V++++ ++T++++ + ++ T++AAL + + +LD + RE +S E+
Sbjct: 1638 RTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA 1697
Query: 301 FITK 304
T+
Sbjct: 1698 LHTE 1701
>AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein.
Length = 526
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 261
>AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing
oxidoreductase isoform FORII protein.
Length = 414
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 261
>AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein.
Length = 414
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 261
>AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein.
Length = 363
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 261
>AF217490-1|AAF78197.1| 191|Homo sapiens fragile 16D oxido
reductase protein.
Length = 191
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 32 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 89
>AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing
protein WWOX protein.
Length = 414
Score = 33.1 bits (72), Expect = 3.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 218 VHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINE 277
+H + + PW++T+D L QV LGH +Q L ++ R++ A ++ V +E
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQV-NHLGHFYL-VQLLQDVLCRSAPARVIVVSSE 261
>AK129776-1|BAC85232.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ26265 fis, clone DMC05516, highly similar to Ig
gamma-1 chain C region. ).
Length = 472
Score = 31.5 bits (68), Expect = 9.6
Identities = 18/90 (20%), Positives = 36/90 (40%)
Query: 186 FGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQV 245
+GGNPD +G G+ T P L + + SG A + +D + V
Sbjct: 122 YGGNPDSFDAWGQGTMVTVGSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV 181
Query: 246 AEALGHIVTNIQELSEIFTRTSVAALMAVI 275
+ G + + + + + + +L +V+
Sbjct: 182 SWNSGALTSGVHTFPAVLQSSGLYSLSSVV 211
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.137 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,096,546
Number of Sequences: 224733
Number of extensions: 3761326
Number of successful extensions: 7219
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 6861
Number of HSP's gapped (non-prelim): 253
length of query: 650
length of database: 73,234,838
effective HSP length: 95
effective length of query: 555
effective length of database: 51,885,203
effective search space: 28796287665
effective search space used: 28796287665
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
- SilkBase 1999-2023 -