Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002693-TA|BGIBMGA002693-PA|IPR006162|Phosphopantetheine
attachment site, IPR001849|Pleckstrin-like,
IPR001331|Guanine-nucleotide dissociation stimulator, CDC24,
IPR000219|DH
(749 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16L87 Cluster: Dbl; n=3; Fungi/Metazoa group|Rep: Dbl ... 475 e-132
UniRef50_UPI0000DB73BC Cluster: PREDICTED: similar to Guanine nu... 427 e-118
UniRef50_Q7K4E0 Cluster: LD43457p; n=2; Sophophora|Rep: LD43457p... 390 e-107
UniRef50_UPI0000F34917 Cluster: UPI0000F34917 related cluster; n... 269 2e-70
UniRef50_Q4S0P7 Cluster: Chromosome 2 SCAF14781, whole genome sh... 267 6e-70
UniRef50_O15068 Cluster: Guanine nucleotide exchange factor DBS;... 267 6e-70
UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-... 261 4e-68
UniRef50_Q4SVF8 Cluster: Chromosome 7 SCAF13760, whole genome sh... 230 9e-59
UniRef50_A7SVF8 Cluster: Predicted protein; n=1; Nematostella ve... 206 2e-51
UniRef50_Q4RP67 Cluster: Chromosome 1 SCAF15008, whole genome sh... 191 5e-47
UniRef50_Q4SUB9 Cluster: Chromosome 3 SCAF13974, whole genome sh... 171 4e-41
UniRef50_A7RXC9 Cluster: Predicted protein; n=1; Nematostella ve... 171 4e-41
UniRef50_O60229 Cluster: Kalirin; n=25; Eumetazoa|Rep: Kalirin -... 171 4e-41
UniRef50_Q4RY59 Cluster: Chromosome 3 SCAF14978, whole genome sh... 168 4e-40
UniRef50_O75962 Cluster: Triple functional domain protein; n=71;... 167 1e-39
UniRef50_UPI0000D5595A Cluster: PREDICTED: similar to CG18214-PA... 165 4e-39
UniRef50_UPI000065F2B5 Cluster: Huntingtin-associated protein-in... 165 4e-39
UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet; n... 164 9e-39
UniRef50_Q7KY09 Cluster: Trio; n=10; Diptera|Rep: Trio - Drosoph... 163 1e-38
UniRef50_Q1RLV0 Cluster: Zgc:136817; n=3; Danio rerio|Rep: Zgc:1... 163 2e-38
UniRef50_UPI000058400D Cluster: PREDICTED: hypothetical protein;... 162 3e-38
UniRef50_UPI0000F211CF Cluster: PREDICTED: similar to RAC/CDC42 ... 154 7e-36
UniRef50_Q6DN89 Cluster: Quattro; n=2; Eumetazoa|Rep: Quattro - ... 154 1e-35
UniRef50_Q96PX9 Cluster: KIAA1909 protein; n=12; Euteleostomi|Re... 154 1e-35
UniRef50_UPI0000F1E6F8 Cluster: PREDICTED: hypothetical protein;... 153 2e-35
UniRef50_UPI0000F1E2DD Cluster: PREDICTED: similar to RAC/CDC42 ... 149 4e-34
UniRef50_UPI00004D56CF Cluster: Puratrophin-1 (Pleckstrin homolo... 148 5e-34
UniRef50_UPI000065D244 Cluster: Triple functional domain protein... 147 8e-34
UniRef50_Q86YR7 Cluster: Rho family guanine-nucleotide exchange ... 147 1e-33
UniRef50_O02133 Cluster: Temporarily assigned gene name protein ... 146 1e-33
UniRef50_Q86VW2 Cluster: RhoA/RAC/CDC42 exchange factor; n=52; T... 146 3e-33
UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio "Qu... 145 3e-33
UniRef50_UPI00015B51B1 Cluster: PREDICTED: similar to conserved ... 144 8e-33
UniRef50_UPI0000F21533 Cluster: PREDICTED: hypothetical protein;... 143 1e-32
UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n... 143 1e-32
UniRef50_Q58EX7 Cluster: Puratrophin-1; n=18; Eutheria|Rep: Pura... 142 4e-32
UniRef50_UPI0000F2B983 Cluster: PREDICTED: similar to FLJ00068 p... 140 1e-31
UniRef50_UPI00005A5680 Cluster: PREDICTED: similar to pleckstrin... 139 3e-31
UniRef50_Q17DQ5 Cluster: Putative uncharacterized protein; n=1; ... 137 1e-30
UniRef50_UPI0001554F5B Cluster: PREDICTED: similar to FLJ00068 p... 136 2e-30
UniRef50_O61528 Cluster: Guanine nucleotide exchange factor UNC-... 135 5e-30
UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whol... 134 6e-30
UniRef50_Q7KU89 Cluster: CG33275-PA, isoform A; n=7; Diptera|Rep... 131 6e-29
UniRef50_A0NEN5 Cluster: ENSANGP00000031634; n=2; Culicidae|Rep:... 128 4e-28
UniRef50_UPI0000519A5C Cluster: PREDICTED: similar to CG33275-PC... 126 2e-27
UniRef50_Q7Z2K2 Cluster: Transforming gene product TGAT; n=2; Eu... 125 5e-27
UniRef50_UPI00015B606E Cluster: PREDICTED: similar to ENSANGP000... 123 2e-26
UniRef50_UPI0000D55959 Cluster: PREDICTED: similar to CG18214-PD... 122 5e-26
UniRef50_UPI0000F210AF Cluster: PREDICTED: hypothetical protein;... 121 8e-26
UniRef50_UPI00015A58C2 Cluster: Pleckstrin homology domain-conta... 121 8e-26
UniRef50_Q4RTS6 Cluster: Chromosome 2 SCAF14997, whole genome sh... 120 2e-25
UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome s... 119 3e-25
UniRef50_UPI0000E80D31 Cluster: PREDICTED: hypothetical protein;... 116 3e-24
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ... 114 9e-24
UniRef50_Q4RFA4 Cluster: Chromosome 8 SCAF15119, whole genome sh... 109 2e-22
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -... 109 3e-22
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep... 108 5e-22
UniRef50_A1L390 Cluster: Pleckstrin homology domain-containing f... 108 6e-22
UniRef50_UPI0000EB3077 Cluster: pleckstrin homology domain conta... 107 1e-21
UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ... 107 1e-21
UniRef50_Q4S810 Cluster: Chromosome 9 SCAF14710, whole genome sh... 107 1e-21
UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing f... 106 2e-21
UniRef50_Q4VAC9 Cluster: Pleckstrin homology domain-containing f... 105 3e-21
UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin... 99 2e-19
UniRef50_UPI0000D55943 Cluster: PREDICTED: similar to Pleckstrin... 97 2e-18
UniRef50_Q3B839 Cluster: BRSK2 protein; n=5; Catarrhini|Rep: BRS... 93 2e-17
UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin... 91 8e-17
UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome s... 91 1e-16
UniRef50_Q4SB72 Cluster: Chromosome undetermined SCAF14677, whol... 89 4e-16
UniRef50_UPI0000DA3D65 Cluster: PREDICTED: similar to mcf.2 tran... 89 5e-16
UniRef50_Q9H7P9 Cluster: Pleckstrin homology domain-containing f... 89 5e-16
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ... 88 7e-16
UniRef50_Q8TER5 Cluster: FLJ00128 protein; n=30; Tetrapoda|Rep: ... 88 7e-16
UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s... 87 1e-15
UniRef50_UPI0001555B97 Cluster: PREDICTED: similar to FLJ00056 p... 87 2e-15
UniRef50_A7SFH2 Cluster: Predicted protein; n=1; Nematostella ve... 86 3e-15
UniRef50_UPI0000F3273F Cluster: pleckstrin homology domain conta... 85 7e-15
UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh... 85 7e-15
UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000... 85 9e-15
UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckst... 85 9e-15
UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob... 84 1e-14
UniRef50_UPI000065DEA3 Cluster: Homolog of Brachydanio rerio "Qu... 83 3e-14
UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB... 83 4e-14
UniRef50_Q4SQR9 Cluster: Chromosome undetermined SCAF14531, whol... 83 4e-14
UniRef50_A1ZBA1 Cluster: CG30115-PD, isoform D; n=4; Sophophora|... 80 2e-13
UniRef50_UPI0000DA28FB Cluster: PREDICTED: similar to DEP domain... 79 3e-13
UniRef50_UPI000069EC71 Cluster: CDNA FLJ43173 fis, clone FCBBF30... 79 6e-13
UniRef50_Q17LU2 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12
UniRef50_UPI0000E463E9 Cluster: PREDICTED: similar to Cdc42 guan... 76 4e-12
UniRef50_A2A2X3 Cluster: MCF.2 cell line derived transforming se... 75 5e-12
UniRef50_Q70Z35 Cluster: DEP domain-containing protein 2 (Phosph... 75 5e-12
UniRef50_UPI0000F1FC93 Cluster: PREDICTED: hypothetical protein;... 75 7e-12
UniRef50_UPI0000D575D3 Cluster: PREDICTED: similar to Rho guanin... 73 4e-11
UniRef50_A0NBJ0 Cluster: ENSANGP00000029817; n=1; Anopheles gamb... 70 2e-10
UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep: ... 70 3e-10
UniRef50_Q4RXW9 Cluster: Chromosome 11 SCAF14979, whole genome s... 69 4e-10
UniRef50_Q54YP1 Cluster: Pleckstrin homology (PH) domain-contain... 69 4e-10
UniRef50_Q7QGJ0 Cluster: ENSANGP00000019802; n=4; Culicidae|Rep:... 67 1e-09
UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;... 66 3e-09
UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor ... 66 3e-09
UniRef50_UPI000155FBE9 Cluster: PREDICTED: hypothetical protein;... 66 4e-09
UniRef50_Q96N96 Cluster: Spermatogenesis-associated protein 13; ... 66 4e-09
UniRef50_Q8TCU6 Cluster: Phosphatidylinositol 3,4,5-trisphosphat... 66 4e-09
UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmoduli... 65 6e-09
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 64 1e-08
UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein;... 64 1e-08
UniRef50_Q4SFB4 Cluster: Chromosome 6 SCAF14605, whole genome sh... 64 1e-08
UniRef50_O96035 Cluster: PEM-2; n=1; Ciona savignyi|Rep: PEM-2 -... 63 2e-08
UniRef50_Q4SIP5 Cluster: Chromosome 21 SCAF14577, whole genome s... 62 4e-08
UniRef50_Q17KZ4 Cluster: Putative uncharacterized protein; n=2; ... 62 4e-08
UniRef50_Q4SEL7 Cluster: Chromosome 10 SCAF14616, whole genome s... 62 5e-08
UniRef50_P40995 Cluster: Rho guanine nucleotide exchange factor ... 62 7e-08
UniRef50_Q96PE2 Cluster: Rho guanine nucleotide exchange factor ... 62 7e-08
UniRef50_UPI00015A61A4 Cluster: UPI00015A61A4 related cluster; n... 61 9e-08
UniRef50_P98174 Cluster: FYVE, RhoGEF and PH domain-containing p... 61 1e-07
UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,... 60 2e-07
UniRef50_Q54VX2 Cluster: Pleckstrin homology (PH) domain-contain... 60 2e-07
UniRef50_A2QIY3 Cluster: Complex: the S. pombe proteins scd1; n=... 59 4e-07
UniRef50_UPI0000EB2613 Cluster: UPI0000EB2613 related cluster; n... 59 5e-07
UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome s... 59 5e-07
UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol... 58 9e-07
UniRef50_Q7Z6J4 Cluster: FYVE, RhoGEF and PH domain-containing p... 58 9e-07
UniRef50_Q960B3 Cluster: SD09786p; n=4; Sophophora|Rep: SD09786p... 58 1e-06
UniRef50_UPI0000E477CD Cluster: PREDICTED: similar to GH10341p; ... 57 2e-06
UniRef50_Q16JM6 Cluster: Rho guanine exchange factor; n=2; Culic... 57 2e-06
UniRef50_Q9HF59 Cluster: Cdc24; n=2; Saccharomycetaceae|Rep: Cdc... 57 2e-06
UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoG... 57 2e-06
UniRef50_Q4RP06 Cluster: Chromosome 10 SCAF15009, whole genome s... 56 3e-06
UniRef50_Q17KZ0 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-06
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 56 3e-06
UniRef50_Q1ZYL3 Cluster: Rho guanine nucleotide exchange factor ... 56 5e-06
UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin, ... 55 6e-06
UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella ve... 54 1e-05
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 54 1e-05
UniRef50_Q54GP2 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-05
UniRef50_UPI0000E46C3C Cluster: PREDICTED: hypothetical protein;... 54 2e-05
UniRef50_Q18372 Cluster: Putative uncharacterized protein exc-5;... 53 2e-05
UniRef50_UPI000049A2CA Cluster: Rho guanine nucleotide exchange ... 53 3e-05
UniRef50_Q9GTU9 Cluster: Rho guanine nucleotide exchange factor ... 53 3e-05
UniRef50_P11433 Cluster: Cell division control protein 24; n=3; ... 53 3e-05
UniRef50_Q13009 Cluster: T-lymphoma invasion and metastasis-indu... 52 4e-05
UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoG... 52 6e-05
UniRef50_Q4SSS2 Cluster: Chromosome undetermined SCAF14347, whol... 52 6e-05
UniRef50_Q1RPY9 Cluster: Zinc finger protein; n=1; Ciona intesti... 52 6e-05
UniRef50_UPI00015B5708 Cluster: PREDICTED: similar to ENSANGP000... 52 8e-05
UniRef50_UPI0000F2BEF5 Cluster: PREDICTED: similar to Rho guanin... 52 8e-05
UniRef50_UPI000065F5D5 Cluster: Rho guanine nucleotide exchange ... 51 1e-04
UniRef50_O00886 Cluster: RacGAP protein; n=2; Dictyostelium disc... 51 1e-04
UniRef50_P91621 Cluster: Protein still life, isoform SIF type 1;... 51 1e-04
UniRef50_A1ZAQ4 Cluster: CG15611-PA, isoform A; n=5; Sophophora|... 50 2e-04
UniRef50_A0CZ33 Cluster: Chromosome undetermined scaffold_31, wh... 50 2e-04
UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis... 50 2e-04
UniRef50_Q4PBU1 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-04
UniRef50_Q4TC49 Cluster: Chromosome undetermined SCAF7053, whole... 50 2e-04
UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2... 50 2e-04
UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella ve... 50 2e-04
UniRef50_Q5JSP0 Cluster: FYVE, RhoGEF and PH domain-containing p... 50 2e-04
UniRef50_UPI0000DB6CBB Cluster: PREDICTED: similar to dynamin bi... 50 3e-04
UniRef50_UPI0000498C66 Cluster: actin-binding protein; n=1; Enta... 50 3e-04
UniRef50_Q4RJT9 Cluster: Chromosome 9 SCAF15033, whole genome sh... 49 4e-04
UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2; Dictyo... 49 4e-04
UniRef50_Q54BY9 Cluster: Pleckstrin homology (PH) domain-contain... 49 4e-04
UniRef50_O94989 Cluster: Rho guanine nucleotide exchange factor ... 49 4e-04
UniRef50_UPI0000499324 Cluster: Rho guanine nucleotide exchange ... 49 5e-04
UniRef50_Q54T65 Cluster: RhoGEF domain-containing protein; n=1; ... 49 5e-04
UniRef50_Q54DW7 Cluster: Pleckstrin homology (PH) domain-contain... 49 5e-04
UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor ... 49 5e-04
UniRef50_UPI000155BD3A Cluster: PREDICTED: hypothetical protein,... 48 7e-04
UniRef50_UPI0001555442 Cluster: PREDICTED: similar to FYVE, RhoG... 48 7e-04
UniRef50_Q5KDK5 Cluster: Protein binding protein, putative; n=2;... 48 7e-04
UniRef50_UPI0000E8080B Cluster: PREDICTED: similar to TUBA; n=3;... 48 0.001
UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange ... 48 0.001
UniRef50_UPI0000ECB580 Cluster: UPI0000ECB580 related cluster; n... 48 0.001
UniRef50_Q54SG9 Cluster: RhoGEF domain-containing protein; n=2; ... 48 0.001
UniRef50_A0C114 Cluster: Chromosome undetermined scaffold_140, w... 48 0.001
UniRef50_UPI0000F1F644 Cluster: PREDICTED: hypothetical protein;... 48 0.001
UniRef50_UPI0000F1DCF3 Cluster: PREDICTED: hypothetical protein;... 48 0.001
UniRef50_Q5RH33 Cluster: Novel protein similar to human and mous... 48 0.001
UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing p... 48 0.001
UniRef50_UPI0000499563 Cluster: 158792 GrfA protein; n=1; Entamo... 47 0.002
UniRef50_Q4SFX7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 47 0.002
UniRef50_UPI00006A1ACD Cluster: FYVE, RhoGEF and PH domain-conta... 46 0.003
UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.003
UniRef50_UPI000049A4D9 Cluster: Rho guanine nucleotide exchange ... 46 0.004
UniRef50_Q4SCD4 Cluster: Chromosome undetermined SCAF14659, whol... 46 0.004
UniRef50_Q86HN1 Cluster: Similar to PH (Pleckstrin homology) dom... 46 0.005
UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4... 46 0.005
UniRef50_A0CQC8 Cluster: Chromosome undetermined scaffold_24, wh... 46 0.005
UniRef50_Q4PGM7 Cluster: Putative uncharacterized protein; n=1; ... 46 0.005
UniRef50_A5DJC8 Cluster: Putative uncharacterized protein; n=1; ... 46 0.005
UniRef50_Q8N5V2 Cluster: Ephexin-1; n=32; Euteleostomi|Rep: Ephe... 46 0.005
UniRef50_Q6ZV73 Cluster: FYVE, RhoGEF and PH domain-containing p... 46 0.005
UniRef50_UPI0000E494A0 Cluster: PREDICTED: similar to FGD6 prote... 45 0.007
UniRef50_Q1RMS9 Cluster: FGD6 protein; n=11; Amniota|Rep: FGD6 p... 45 0.007
UniRef50_A0D0E6 Cluster: Chromosome undetermined scaffold_33, wh... 45 0.007
UniRef50_A0BKK3 Cluster: Chromosome undetermined scaffold_112, w... 45 0.007
UniRef50_A4R6Z2 Cluster: Putative uncharacterized protein; n=2; ... 45 0.007
UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome sh... 45 0.009
UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-contain... 45 0.009
UniRef50_Q9NHV9 Cluster: Protein vav; n=6; Diptera|Rep: Protein ... 45 0.009
UniRef50_UPI00015B49F8 Cluster: PREDICTED: similar to conserved ... 44 0.015
UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti... 44 0.015
UniRef50_UPI00004992B4 Cluster: Rho guanine nucleotide exchange ... 44 0.015
UniRef50_Q6FIT2 Cluster: Candida glabrata strain CBS138 chromoso... 44 0.015
UniRef50_Q11100 Cluster: Putative protein tag-52; n=2; Caenorhab... 44 0.015
UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor ... 44 0.015
UniRef50_UPI000049A257 Cluster: Rho guanine nucleotide exchange ... 44 0.020
UniRef50_A7S9N2 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.020
UniRef50_Q4P2N2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.020
UniRef50_A6R7R1 Cluster: Predicted protein; n=1; Ajellomyces cap... 44 0.020
UniRef50_UPI0000E4A769 Cluster: PREDICTED: similar to vav 2 onco... 43 0.026
UniRef50_UPI0000DA2C9A Cluster: PREDICTED: similar to FYVE, RhoG... 43 0.026
UniRef50_UPI000069E0AF Cluster: Proto-oncogene DBL (Proto-oncoge... 43 0.026
UniRef50_Q4RBE6 Cluster: Chromosome undetermined SCAF21594, whol... 43 0.026
UniRef50_Q17DC1 Cluster: Still life, putative; n=5; Endopterygot... 43 0.026
UniRef50_Q9NVK9 Cluster: CDNA FLJ10665 fis, clone NT2RP2006200; ... 43 0.026
UniRef50_Q9NR81 Cluster: Rho guanine nucleotide exchange factor ... 43 0.026
UniRef50_UPI00015B40BC Cluster: PREDICTED: similar to GA20259-PA... 43 0.035
UniRef50_UPI0000DB6C3F Cluster: PREDICTED: similar to CG7397-PA;... 43 0.035
UniRef50_UPI00004983B6 Cluster: cell division control protein CD... 43 0.035
UniRef50_UPI0000ECD505 Cluster: Rho guanine nucleotide exchange ... 43 0.035
UniRef50_Q4RXA2 Cluster: Chromosome 11 SCAF14979, whole genome s... 43 0.035
UniRef50_Q17AI6 Cluster: Guanine nucleotide exchange factor; n=3... 43 0.035
UniRef50_Q5TEV1 Cluster: Rho guanine nucleotide exchange factor ... 43 0.035
UniRef50_Q8IW93 Cluster: Rho guanine nucleotide exchange factor ... 43 0.035
UniRef50_UPI0000E48DF2 Cluster: PREDICTED: similar to Bcr protei... 42 0.046
UniRef50_UPI000049A5B0 Cluster: Rho guanine nucleotide exchange ... 42 0.046
UniRef50_UPI000049944B Cluster: Rho guanine nucleotide exchange ... 42 0.046
UniRef50_Q4S5A8 Cluster: Chromosome 19 SCAF14731, whole genome s... 42 0.046
UniRef50_Q9VS45 Cluster: CG8606-PA, isoform A; n=4; Sophophora|R... 42 0.046
UniRef50_Q54PK2 Cluster: Putative uncharacterized protein; n=1; ... 42 0.046
UniRef50_Q54B37 Cluster: Pleckstrin homology (PH) domain-contain... 42 0.046
UniRef50_A0CIG3 Cluster: Chromosome undetermined scaffold_19, wh... 42 0.046
UniRef50_Q7S4Y3 Cluster: Putative uncharacterized protein NCU060... 42 0.046
UniRef50_UPI0000DB6D3E Cluster: PREDICTED: similar to RhoGEF2 CG... 42 0.061
UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanin... 42 0.061
UniRef50_UPI0000499FFA Cluster: Rho guanine nucleotide exchange ... 42 0.061
UniRef50_Q7ZZ90 Cluster: Novel protein similar to human MCF.2 ce... 42 0.061
UniRef50_Q4RFR9 Cluster: Chromosome 16 SCAF15113, whole genome s... 42 0.061
UniRef50_Q86B45 Cluster: CG8557-PB, isoform B; n=2; Drosophila m... 42 0.061
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.061
UniRef50_A0D4V7 Cluster: Chromosome undetermined scaffold_38, wh... 42 0.061
UniRef50_Q6CBW7 Cluster: Yarrowia lipolytica chromosome C of str... 42 0.061
UniRef50_Q6GLN1 Cluster: LOC443708 protein; n=2; Xenopus|Rep: LO... 42 0.080
UniRef50_A3QJZ2 Cluster: Novel protein similar to vertebrate Rho... 42 0.080
UniRef50_A0CSX7 Cluster: Chromosome undetermined scaffold_26, wh... 42 0.080
UniRef50_UPI0000F208BC Cluster: PREDICTED: hypothetical protein;... 41 0.11
UniRef50_UPI0000E46F96 Cluster: PREDICTED: hypothetical protein;... 41 0.11
UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,... 41 0.11
UniRef50_UPI0000D5630B Cluster: PREDICTED: similar to CG7323-PA;... 41 0.11
UniRef50_UPI0000D55C29 Cluster: PREDICTED: similar to CG8606-PA,... 41 0.11
UniRef50_Q54SR5 Cluster: Putative uncharacterized protein; n=1; ... 41 0.11
UniRef50_Q5KH40 Cluster: Expressed protein; n=3; Filobasidiella ... 41 0.11
UniRef50_Q5VV41 Cluster: Rho guanine nucleotide exchange factor ... 41 0.11
UniRef50_UPI0000E47242 Cluster: PREDICTED: hypothetical protein;... 41 0.14
UniRef50_UPI0000499880 Cluster: conserved hypothetical protein; ... 41 0.14
UniRef50_Q4RG84 Cluster: Chromosome 2 SCAF15106, whole genome sh... 41 0.14
UniRef50_Q9N2V4 Cluster: Putative uncharacterized protein; n=3; ... 41 0.14
UniRef50_Q550V3 Cluster: Pleckstrin homology (PH) domain-contain... 41 0.14
UniRef50_Q1ZXH8 Cluster: Pleckstrin homology (PH) domain-contain... 41 0.14
UniRef50_A7SXH1 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.14
UniRef50_Q1E796 Cluster: Putative uncharacterized protein; n=1; ... 41 0.14
UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; ... 41 0.14
UniRef50_O59679 Cluster: Rho guanine nucleotide exchange factor ... 41 0.14
UniRef50_UPI0000DB72CE Cluster: PREDICTED: similar to CG7323-PA;... 40 0.19
UniRef50_UPI000051AA4C Cluster: PREDICTED: similar to rho-type g... 40 0.19
UniRef50_UPI0000498ACC Cluster: Rho guanine nucleotide exchange ... 40 0.19
UniRef50_Q7PLZ7 Cluster: ENSANGP00000002929; n=4; Endopterygota|... 40 0.19
UniRef50_Q5BY51 Cluster: SJCHGC03397 protein; n=1; Schistosoma j... 40 0.19
UniRef50_Q22U30 Cluster: Cyclic nucleotide-binding domain contai... 40 0.19
UniRef50_A7SEJ8 Cluster: Predicted protein; n=2; Nematostella ve... 40 0.19
UniRef50_Q5T286 Cluster: Novel protein; n=8; Theria|Rep: Novel p... 40 0.19
UniRef50_Q4P5Y6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.19
UniRef50_Q6XZF7 Cluster: Dynamin-binding protein; n=12; Eutheria... 40 0.19
UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor ... 40 0.19
UniRef50_UPI000049976C Cluster: hypothetical protein 115.t00004;... 40 0.25
UniRef50_UPI0000498473 Cluster: Rho guanine nucleotide exchange ... 40 0.25
UniRef50_Q4SPD4 Cluster: Chromosome 16 SCAF14537, whole genome s... 40 0.25
UniRef50_Q17J92 Cluster: Putative uncharacterized protein; n=1; ... 40 0.25
UniRef50_Q7Z628 Cluster: Neuroepithelial cell-transforming gene ... 40 0.25
UniRef50_UPI0000E46C03 Cluster: PREDICTED: similar to Intersecti... 40 0.32
UniRef50_Q4SQQ5 Cluster: Chromosome undetermined SCAF14531, whol... 40 0.32
UniRef50_Q1LYR1 Cluster: Novel protein; n=5; Danio rerio|Rep: No... 40 0.32
UniRef50_Q8IFN3 Cluster: Putative uncharacterized protein PFD110... 40 0.32
UniRef50_Q54S15 Cluster: Pleckstrin homology (PH) domain-contain... 40 0.32
UniRef50_Q29I70 Cluster: GA21162-PA; n=2; pseudoobscura subgroup... 40 0.32
UniRef50_UPI0000F210FE Cluster: PREDICTED: hypothetical protein;... 39 0.43
UniRef50_UPI0000E49080 Cluster: PREDICTED: hypothetical protein;... 39 0.43
UniRef50_UPI0000E47B1C Cluster: PREDICTED: similar to TUBA; n=2;... 39 0.43
UniRef50_Q4SEN6 Cluster: Chromosome undetermined SCAF14615, whol... 39 0.43
UniRef50_Q54C56 Cluster: Putative uncharacterized protein; n=1; ... 39 0.43
UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep: ... 39 0.43
UniRef50_UPI00006CB721 Cluster: RhoGEF domain containing protein... 39 0.57
UniRef50_UPI000051A437 Cluster: PREDICTED: similar to RhoGEF4 CG... 39 0.57
UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Interse... 39 0.57
UniRef50_Q4TC03 Cluster: Chromosome undetermined SCAF7065, whole... 39 0.57
UniRef50_Q54P81 Cluster: Putative uncharacterized protein; n=1; ... 39 0.57
UniRef50_Q5SVK9 Cluster: Novel protein; n=2; Euteleostomi|Rep: N... 39 0.57
UniRef50_UPI000069FF5A Cluster: Dynamin-binding protein (Scaffol... 38 0.75
UniRef50_Q4SNE1 Cluster: Chromosome 8 SCAF14543, whole genome sh... 38 0.75
UniRef50_A3VDA4 Cluster: Putative quinoprotein; n=1; Rhodobacter... 38 0.75
UniRef50_Q4XWP8 Cluster: Putative uncharacterized protein; n=3; ... 38 0.75
UniRef50_A2FCU5 Cluster: Kelch motif family protein; n=1; Tricho... 38 0.75
UniRef50_O94827 Cluster: Pleckstrin homology domain-containing f... 38 0.75
UniRef50_Q4PFT1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.75
UniRef50_UPI0000F2E47F Cluster: PREDICTED: similar to zinc finge... 38 0.99
UniRef50_UPI0000499B27 Cluster: Rho guanine nucleotide exchange ... 38 0.99
UniRef50_Q4T8E6 Cluster: Chromosome undetermined SCAF7822, whole... 38 0.99
UniRef50_Q4SPQ5 Cluster: Chromosome 16 SCAF14537, whole genome s... 38 0.99
UniRef50_Q8IQ97 Cluster: CG8114-PB, isoform B; n=9; Diptera|Rep:... 38 0.99
UniRef50_Q54MM3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.99
UniRef50_A7SS01 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.99
UniRef50_A7RK39 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.99
UniRef50_Q875H9 Cluster: Guanine nucleotide exchange factor Cdc2... 38 0.99
UniRef50_UPI00006CC97C Cluster: RhoGEF domain containing protein... 38 1.3
UniRef50_UPI000049978D Cluster: Rho guanine nucleotide exchange ... 38 1.3
UniRef50_Q49U75 Cluster: PDZ-RhoGEF; n=2; Danio rerio|Rep: PDZ-R... 38 1.3
UniRef50_A7S9L2 Cluster: Predicted protein; n=1; Nematostella ve... 38 1.3
UniRef50_Q5KF15 Cluster: Putative uncharacterized protein; n=2; ... 38 1.3
UniRef50_A6QW04 Cluster: Putative uncharacterized protein; n=1; ... 38 1.3
UniRef50_A5E275 Cluster: Putative uncharacterized protein; n=1; ... 38 1.3
UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int... 38 1.3
UniRef50_O15085 Cluster: Rho guanine nucleotide exchange factor ... 38 1.3
UniRef50_UPI00006CCA26 Cluster: Glutathione peroxidase family pr... 37 1.7
UniRef50_UPI000049A432 Cluster: Rho guanine nucleotide exchange ... 37 1.7
UniRef50_UPI000049943D Cluster: Rho guanine nucleotide exchange ... 37 1.7
UniRef50_UPI0000498513 Cluster: Rho guanine nucleotide exchange ... 37 1.7
UniRef50_UPI00004984D8 Cluster: protein with RhoGEF and ArfGAP d... 37 1.7
UniRef50_Q504F6 Cluster: Zgc:109904; n=5; Euteleostomi|Rep: Zgc:... 37 1.7
UniRef50_Q4SU01 Cluster: Chromosome 7 SCAF14053, whole genome sh... 37 1.7
UniRef50_Q4S675 Cluster: Chromosome 9 SCAF14729, whole genome sh... 37 1.7
UniRef50_A6S9L4 Cluster: Putative uncharacterized protein; n=2; ... 37 1.7
UniRef50_A2QSA9 Cluster: Contig An08c0250, complete genome; n=1;... 37 1.7
UniRef50_O94887 Cluster: FERM, RhoGEF and pleckstrin domain-cont... 37 1.7
UniRef50_Q12774 Cluster: Rho guanine nucleotide exchange factor ... 37 1.7
UniRef50_UPI0000E48610 Cluster: PREDICTED: similar to Rho guanin... 37 2.3
UniRef50_UPI0000DB70D0 Cluster: PREDICTED: similar to pebble CG8... 37 2.3
UniRef50_UPI000049A230 Cluster: hypothetical protein 13.t00058; ... 37 2.3
UniRef50_Q4R811 Cluster: Testis cDNA clone: QtsA-13821, similar ... 37 2.3
UniRef50_Q965J0 Cluster: Temporarily assigned gene name protein ... 37 2.3
UniRef50_Q55G61 Cluster: Putative uncharacterized protein; n=1; ... 37 2.3
UniRef50_Q556I3 Cluster: Putative uncharacterized protein; n=2; ... 37 2.3
UniRef50_Q553D3 Cluster: Pleckstrin homology (PH) domain-contain... 37 2.3
UniRef50_Q4Z136 Cluster: Putative uncharacterized protein; n=1; ... 37 2.3
UniRef50_Q2MCX4 Cluster: Trix, Rac guanine nucleotide exchange f... 37 2.3
UniRef50_A7S3B5 Cluster: Predicted protein; n=1; Nematostella ve... 37 2.3
UniRef50_A7RVX0 Cluster: Predicted protein; n=1; Nematostella ve... 37 2.3
UniRef50_Q5KI94 Cluster: GrfA protein, putative; n=2; Filobasidi... 37 2.3
UniRef50_Q9UTR5 Cluster: Rho1 guanine nucleotide exchange factor... 37 2.3
UniRef50_Q9Y7U6 Cluster: Rho1 guanine nucleotide exchange factor... 37 2.3
UniRef50_UPI0000E2181D Cluster: PREDICTED: rho guanine nucleotid... 36 3.0
UniRef50_UPI000051A1EA Cluster: PREDICTED: similar to Cdep CG315... 36 3.0
UniRef50_UPI000049864F Cluster: 158792 GrfA protein; n=1; Entamo... 36 3.0
UniRef50_Q4RW86 Cluster: Chromosome 9 SCAF14991, whole genome sh... 36 3.0
UniRef50_A7AP72 Cluster: Putative uncharacterized protein; n=1; ... 36 3.0
UniRef50_A0E7D3 Cluster: Chromosome undetermined scaffold_81, wh... 36 3.0
UniRef50_Q4SME7 Cluster: Chromosome 8 SCAF14552, whole genome sh... 36 4.0
UniRef50_Q4RY71 Cluster: Chromosome 3 SCAF14978, whole genome sh... 36 4.0
UniRef50_Q9MA72 Cluster: F2J6.9 protein; n=1; Arabidopsis thalia... 36 4.0
UniRef50_Q55G27 Cluster: RhoGEF domain-containing protein; n=1; ... 36 4.0
UniRef50_A2FQ63 Cluster: Putative uncharacterized protein; n=1; ... 36 4.0
UniRef50_A2D847 Cluster: Beige/BEACH domain containing protein; ... 36 4.0
UniRef50_A0E1W1 Cluster: Chromosome undetermined scaffold_74, wh... 36 4.0
UniRef50_A6RIQ1 Cluster: Putative uncharacterized protein; n=2; ... 36 4.0
UniRef50_P38398 Cluster: Breast cancer type 1 susceptibility pro... 36 4.0
UniRef50_UPI0000F1FF96 Cluster: PREDICTED: hypothetical protein;... 36 5.3
UniRef50_UPI00006CBB84 Cluster: Zinc carboxypeptidase family pro... 36 5.3
UniRef50_UPI000049A2CD Cluster: hypothetical protein 130.t00020;... 36 5.3
UniRef50_UPI0000499D76 Cluster: hypothetical protein 218.t00007;... 36 5.3
UniRef50_Q6P2U6 Cluster: Serpin peptidase inhibitor, clade B (Ov... 36 5.3
UniRef50_Q8V6L1 Cluster: Putative uncharacterized protein; n=2; ... 36 5.3
UniRef50_A5Z5G7 Cluster: Putative uncharacterized protein; n=1; ... 36 5.3
UniRef50_Q55DL8 Cluster: Putative uncharacterized protein; n=1; ... 36 5.3
UniRef50_Q54J11 Cluster: Putative uncharacterized protein; n=1; ... 36 5.3
UniRef50_Q17LB9 Cluster: Guanine nucleotide exchange factor; n=3... 36 5.3
UniRef50_A7S951 Cluster: Predicted protein; n=1; Nematostella ve... 36 5.3
UniRef50_UPI00015B4785 Cluster: PREDICTED: similar to ENSANGP000... 35 7.0
UniRef50_UPI0000DB6BF4 Cluster: PREDICTED: similar to CG8557-PA,... 35 7.0
UniRef50_UPI00006CFA66 Cluster: Tubulin-tyrosine ligase family p... 35 7.0
UniRef50_UPI0000498BBA Cluster: Rho guanine nucleotide exchange ... 35 7.0
UniRef50_Q4T952 Cluster: Chromosome undetermined SCAF7638, whole... 35 7.0
UniRef50_Q4S825 Cluster: Chromosome 9 SCAF14710, whole genome sh... 35 7.0
UniRef50_Q54NG0 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0
UniRef50_A2F0J5 Cluster: Kelch motif family protein; n=1; Tricho... 35 7.0
UniRef50_A0MTB7 Cluster: Intersectin 1-like protien; n=1; Trichi... 35 7.0
UniRef50_Q2HDD2 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0
UniRef50_Q6ZWI9 Cluster: Ret finger protein-like 4B; n=6; Euther... 35 7.0
UniRef50_UPI00015B425D Cluster: PREDICTED: similar to ENSANGP000... 35 9.2
UniRef50_UPI0000F2CE0F Cluster: PREDICTED: hypothetical protein;... 35 9.2
UniRef50_UPI0000DBF51E Cluster: Rho guanine nucleotide exchange ... 35 9.2
UniRef50_A5X5J0 Cluster: Rho guanine nucleotide exchange factor ... 35 9.2
UniRef50_Q8IIP2 Cluster: Putative uncharacterized protein; n=1; ... 35 9.2
UniRef50_Q7QDX8 Cluster: ENSANGP00000013669; n=2; Culicidae|Rep:... 35 9.2
UniRef50_Q60P11 Cluster: Putative uncharacterized protein CBG224... 35 9.2
UniRef50_Q4UBC4 Cluster: Putative uncharacterized protein; n=1; ... 35 9.2
UniRef50_Q4E1S1 Cluster: Putative uncharacterized protein; n=2; ... 35 9.2
UniRef50_Q09EE4 Cluster: Putative uncharacterized protein; n=2; ... 35 9.2
UniRef50_Q5KIY2 Cluster: Putative uncharacterized protein; n=1; ... 35 9.2
UniRef50_A5DYP7 Cluster: Putative uncharacterized protein; n=1; ... 35 9.2
UniRef50_Q21653 Cluster: Uncharacterized protein R02F2.2; n=1; C... 35 9.2
>UniRef50_Q16L87 Cluster: Dbl; n=3; Fungi/Metazoa group|Rep: Dbl -
Aedes aegypti (Yellowfever mosquito)
Length = 1538
Score = 475 bits (1171), Expect = e-132
Identities = 224/324 (69%), Positives = 266/324 (82%), Gaps = 2/324 (0%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
+++ S++ GY++E+ E L+PP L G+AD+LFGNLHEL+TFH D+FLKDLE CIS
Sbjct: 1046 VAEMGSILK-GYRDEMLSEEMSSLVPPGLQGKADILFGNLHELYTFHNDIFLKDLENCIS 1104
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
TELVALCFV++R+TFFRLYSYYCQNIPRSERLRETLVDTHLFLQ CQ +LGHKLPLAAY
Sbjct: 1105 TTELVALCFVQRRDTFFRLYSYYCQNIPRSERLRETLVDTHLFLQECQKKLGHKLPLAAY 1164
Query: 498 LLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVD 557
LLKPVQRITKYQLLLKDLL++S+ G+ + LQ+ALDCMLVVLKCVNDSMHQIAITG P D
Sbjct: 1165 LLKPVQRITKYQLLLKDLLKFSDTGTCSRELQKALDCMLVVLKCVNDSMHQIAITGFPAD 1224
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
LSQQGELL+Q SF V +E+K HIFLY+KAMLFCK +K HNK+TY FK
Sbjct: 1225 LSQQGELLLQDSFQVWTESKKDLRLRLKTQHRHIFLYQKAMLFCKQGSKTGHNKSTYQFK 1284
Query: 618 HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
H L MSQIGLTESV+GD R+FEVW QGR EVHTI A TVE+K WV IKRVLL+QL+EL
Sbjct: 1285 HWLQMSQIGLTESVRGDPRRFEVWLQGRQEVHTIQANTVEIKNKWVAEIKRVLLNQLEEL 1344
Query: 678 KGERVRQYGLQHHRTLIQTSSWEV 701
KGE+++QYGL +H+ L T+SW++
Sbjct: 1345 KGEKIKQYGL-NHKPLRHTASWDL 1367
>UniRef50_UPI0000DB73BC Cluster: PREDICTED: similar to Guanine
nucleotide exchange factor DBS (DBLs big sister) (MCF2
transforming sequence-like protein); n=2; Apocrita|Rep:
PREDICTED: similar to Guanine nucleotide exchange factor
DBS (DBLs big sister) (MCF2 transforming sequence-like
protein) - Apis mellifera
Length = 1340
Score = 427 bits (1053), Expect = e-118
Identities = 209/345 (60%), Positives = 247/345 (71%), Gaps = 1/345 (0%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
+++ S+I GYK E+ HL+P L+G+ D+LFGNL +++ FH + FLKDLE CIS
Sbjct: 887 VAELGSIIK-GYKMELTNEGMTHLIPAVLIGKGDILFGNLEDIYIFHGETFLKDLENCIS 945
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
TELVALCFV++RE FFRLYSYYCQNIPRSERLRE + + FL ACQ RLGHKLPLAAY
Sbjct: 946 NTELVALCFVQRREVFFRLYSYYCQNIPRSERLREQIQNEPQFLAACQQRLGHKLPLAAY 1005
Query: 498 LLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVD 557
LLKPVQRITKYQLLLKDLL+YS+ S T LQ+ALDCMLVVLKCVNDSMHQ AITG D
Sbjct: 1006 LLKPVQRITKYQLLLKDLLKYSDEPSCCTELQEALDCMLVVLKCVNDSMHQTAITGFGGD 1065
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
L+ QGELL+QGSF V S +K HIFLYEKA +FCK + +HNKATYHFK
Sbjct: 1066 LNAQGELLLQGSFSVWSSSKRERLLRLKPSQRHIFLYEKAFIFCKHSKPQAHNKATYHFK 1125
Query: 618 HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
L MSQIGLTESVKGD R+FE+W QGR EVHTI A TV+VK++WV +IK VL+ QL EL
Sbjct: 1126 RYLKMSQIGLTESVKGDARRFEIWLQGRAEVHTIQASTVDVKQSWVRQIKGVLMSQLAEL 1185
Query: 678 KGERVRQYGLQHHRTLIQTSSWEVSXXXXXXXXXXXXXXXSCDAH 722
KG++ G +H+ L QT SWE S +H
Sbjct: 1186 KGKQNSALGKTNHKPLRQTISWEAQSSISGSLRTLSVDGSSVISH 1230
>UniRef50_Q7K4E0 Cluster: LD43457p; n=2; Sophophora|Rep: LD43457p -
Drosophila melanogaster (Fruit fly)
Length = 1057
Score = 390 bits (959), Expect = e-107
Identities = 186/323 (57%), Positives = 248/323 (76%), Gaps = 5/323 (1%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
+++ +S++ GY + ++ E+ P +L G+A+VLFGNL+E+++FH DVFLKDLE CIS
Sbjct: 634 VNEIASILK-GYYDRLKSDESA---PASLQGKANVLFGNLNEIYSFHNDVFLKDLENCIS 689
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
TE VALCFV++R+ F++LYS+YCQNI RSE+LRETLVDTH+F + CQ+ LGHKLPL AY
Sbjct: 690 VTERVALCFVKRRDKFYQLYSFYCQNIQRSEKLRETLVDTHMFFKECQIGLGHKLPLGAY 749
Query: 498 LLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVD 557
LLKPVQRITKYQLLLKDLL +++ S L+ ALDCML+VLKCVNDSMHQI+ITG D
Sbjct: 750 LLKPVQRITKYQLLLKDLLLFTDNDSCRNELKNALDCMLIVLKCVNDSMHQISITGFSGD 809
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
L++QGELLMQ SF V E+K HIFLY+K++L CK +K+ +NK++Y FK
Sbjct: 810 LAKQGELLMQDSFQVWIESKKDIRLRMKPKRRHIFLYQKSLLLCKQTSKSGYNKSSYQFK 869
Query: 618 HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
D+ MSQIGLTESV GD ++FEVW +GR EV+T+ A T+ VK WV IKRVL +QL++L
Sbjct: 870 SDVKMSQIGLTESVSGDAKRFEVWLKGRQEVYTLQASTIGVKEMWVAEIKRVLFNQLEKL 929
Query: 678 KGERVRQYGLQHHRTLIQTSSWE 700
KG+++ +Y ++ H++L Q SS E
Sbjct: 930 KGDQIARYNIR-HQSLWQKSSCE 951
>UniRef50_UPI0000F34917 Cluster: UPI0000F34917 related cluster; n=2;
Bos taurus|Rep: UPI0000F34917 UniRef100 entry - Bos
Taurus
Length = 821
Score = 269 bits (659), Expect = 2e-70
Identities = 145/314 (46%), Positives = 196/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HL+ L + D+LFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 490 GYAAEMDNPLMTHLISTGLQNKKDILFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 549
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 550 ERMEEF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQKKLDHKLSLDSYLLKPVQRITK 607
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS+ LQ+AL +L +LK VNDSMH IAITG +LS G LLMQ
Sbjct: 608 YQLLLKEMLKYSKSCEGAEDLQEALSSILGILKAVNDSMHLIAITGYEGNLSDLGRLLMQ 667
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 668 GSFSVWTDHKRGHAKVKDLARFKPMQRHLFLHEKAVLFCKRREENGEGYEKAPSYSYKQS 727
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ I APT E+K AWV I++VL QL+ +
Sbjct: 728 LNMTAVGITENVKGDAKKFEIWYNAREEVYIIQAPTPEIKAAWVSEIRKVLTSQLQACR- 786
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 787 EASQHRALEQSQSL 800
>UniRef50_Q4S0P7 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14781, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1108
Score = 267 bits (655), Expect = 6e-70
Identities = 144/310 (46%), Positives = 198/310 (63%), Gaps = 11/310 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P L+P L + +VLFGN+ E++ FH+ FL++LE+ ELV CF+
Sbjct: 572 GYASEMDNPAMLPLIPAPLQNKKEVLFGNMSEIYHFHKRTFLRELEQYTDCPELVGRCFL 631
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
+ R T ++Y YC N PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 632 Q-RMTDLQIYEKYCHNKPRSESLWRQCSDC-AFFQECQKKLEHKLGLDSYLLKPVQRITK 689
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS+ LQ+AL +L +LK VNDSMH IAITG +LS+ G+LLMQ
Sbjct: 690 YQLLLKEMLKYSKTCEGADDLQEALASILGILKAVNDSMHLIAITGYEGNLSELGKLLMQ 749
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +E+K H+FL+EKA+LFCK +N + KA +Y FKH
Sbjct: 750 GSFSVWTEHKKGHAKVKDLARFKPMQRHLFLHEKALLFCKRREENGEGYEKAPSYSFKHS 809
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L MS +G+TE+ KGD +KFE+W + R EV+ + APT +VK WV I++VL QL+ +G
Sbjct: 810 LSMSAVGITENAKGDNKKFEIWCKSREEVYIVQAPTADVKTTWVNEIRKVLTTQLEACRG 869
Query: 680 ERVRQYGLQH 689
+ R++ ++H
Sbjct: 870 IQ-REHLVKH 878
>UniRef50_O15068 Cluster: Guanine nucleotide exchange factor DBS;
n=69; Euteleostomi|Rep: Guanine nucleotide exchange
factor DBS - Homo sapiens (Human)
Length = 1137
Score = 267 bits (655), Expect = 6e-70
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 656 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 715
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 716 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 773
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 774 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 833
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 834 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 893
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 894 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 952
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 953 EASQHRALEQSQSL 966
>UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-2)
[Contains: MCF2-transforming protein; DBL-transforming
protein]; n=36; Tetrapoda|Rep: Proto-oncogene DBL
(Proto-oncogene MCF-2) [Contains: MCF2-transforming
protein; DBL-transforming protein] - Homo sapiens
(Human)
Length = 925
Score = 261 bits (640), Expect = 4e-68
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 520 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 579
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 580 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 637
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 638 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 697
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 698 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 757
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 758 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 817
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 818 KKRKQQDQLTERDKFQIS 835
>UniRef50_Q4SVF8 Cluster: Chromosome 7 SCAF13760, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
SCAF13760, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 942
Score = 230 bits (563), Expect = 9e-59
Identities = 128/270 (47%), Positives = 169/270 (62%), Gaps = 12/270 (4%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E+E P LLP L Q D+LFGN+ E++ VFL+DL+ C+ E V CF+
Sbjct: 565 GYRAEMEDPSLSDLLPSALHSQKDLLFGNMPEIY----QVFLQDLQGCLETPERVGSCFL 620
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
+++E F ++Y YCQN PRSE L D+ F Q CQ +L HKL L +YLLKPVQR+TK
Sbjct: 621 QRKEKF-QVYERYCQNKPRSELLWRQCCDSPFF-QECQKKLEHKLGLDSYLLKPVQRLTK 678
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL++ LQ+ALD ML +LK VNDSMHQIAITG DLSQ G +++Q
Sbjct: 679 YQLLLKELLKHCREERYRQQLQEALDSMLELLKSVNDSMHQIAITGYQGDLSQLGRVVLQ 738
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKNSHNKAT-YHFKHDLL 621
G F V +K H+FLYE A+LFCK ++S ++ Y FK L
Sbjct: 739 GGFSVWISHKRAAVRMKEMARFKPMQRHLFLYEHAVLFCKRRDEDSPDRTPFYSFKSCLR 798
Query: 622 MSQIGLTESVKGDLRKFEVWRQGRCEVHTI 651
+S +G+TESVKGD+RKFE+ GR V+ +
Sbjct: 799 LSAVGVTESVKGDVRKFEICYSGREVVYIV 828
>UniRef50_A7SVF8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 792
Score = 206 bits (502), Expect = 2e-51
Identities = 110/288 (38%), Positives = 164/288 (56%), Gaps = 6/288 (2%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E E+ + +P L Q + +FGN+ E+ FH+ FL++L +C + V F
Sbjct: 509 GYLHEFERAAGK--IPIELFDQRETIFGNIEEILEFHRCDFLEELNKCSETPKSVGKVFT 566
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+R F + Y+ YC+N P SE L++ L++ +++ CQ LGHKLPL AYLLKPVQRITK
Sbjct: 567 ERRGEFEK-YALYCKNKPASEALQQQLINVP-YIRECQANLGHKLPLTAYLLKPVQRITK 624
Query: 508 YQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
YQLLL+++++ ++ + L +A M VL+ +ND MH + G +L G+LL+
Sbjct: 625 YQLLLREMMKNTKNDRIAYMNLMEAFHAMQNVLRHLNDVMHSSGLKGYHGNLGDLGKLLL 684
Query: 567 QGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKA-TYHFKHDLLMSQI 625
Q FLV +FLYEK ++F K ++ A TYHFK+ + S +
Sbjct: 685 QDPFLVWYTGARRKLPPLKGSQRQVFLYEKMVIFSKREEDSTTKDAVTYHFKNSIKTSDV 744
Query: 626 GLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
G+TE++ G KFE+W GR EV + A E+K W+ I+ VLL Q
Sbjct: 745 GITETINGAPLKFELWLPGRTEVFLLQANNSEIKERWISEIRSVLLHQ 792
>UniRef50_Q4RP67 Cluster: Chromosome 1 SCAF15008, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1263
Score = 191 bits (466), Expect = 5e-47
Identities = 104/214 (48%), Positives = 133/214 (62%), Gaps = 9/214 (4%)
Query: 446 FVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRI 505
F ++ F++Y YCQN PRS+ L D H F Q CQ L HKL L +YLLKPVQR+
Sbjct: 879 FESPQKESFQMYECYCQNKPRSDALWRQFSDCHFF-QECQKNLEHKLGLDSYLLKPVQRL 937
Query: 506 TKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
TKYQLLLK+LL+YS T+ LQ AL ML +LK VNDSMHQIAITG D+ + G +L
Sbjct: 938 TKYQLLLKELLKYSTDCKGTSELQGALTAMLDLLKSVNDSMHQIAITGYEGDICELGRVL 997
Query: 566 MQGSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN---SHNKATYHFK 617
MQGSF V +K H+FLYE+A+LFCK ++ +Y FK
Sbjct: 998 MQGSFSVWISHKRGPTRMKELARFKPMQRHLFLYERALLFCKRREEHGDGGDKTPSYSFK 1057
Query: 618 HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTI 651
H L M+ +G+TE+VKGD +KFE+W GR EV+ +
Sbjct: 1058 HCLKMTAVGITENVKGDQKKFEIWYSGREEVYVV 1091
Score = 71.7 bits (168), Expect = 7e-11
Identities = 29/62 (46%), Positives = 41/62 (66%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E+E P LLPP L + D+LFGN+ E++ FH +FL+DLE C+ E V CF+
Sbjct: 779 GYRAEMENPALSSLLPPILHSKQDILFGNMPEIYNFHSRIFLQDLEGCLETPESVGACFL 838
Query: 448 EK 449
E+
Sbjct: 839 ER 840
>UniRef50_Q4SUB9 Cluster: Chromosome 3 SCAF13974, whole genome shotgun
sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 3
SCAF13974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2492
Score = 171 bits (417), Expect = 4e-41
Identities = 96/272 (35%), Positives = 158/272 (58%), Gaps = 10/272 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+ +++ +H+D FL +LERC+ +L+A F+ + E +Y YC
Sbjct: 2070 IPEDMRGKDKIVFGNIQQIYDWHRDFFLVELERCLQNHDLLADLFI-RHERRLHMYVVYC 2128
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRY-SE 520
QN PRSE L +++ F + Q + ++ ++ YL+KP+QRITKYQLLLKD L+Y S+
Sbjct: 2129 QNKPRSEFL---VIEYEKFFEEIQHEISCRMSVSDYLIKPIQRITKYQLLLKDFLKYTSK 2185
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G +++AL+ M +V K ND M+ + G L+ QG+LL Q +F V ++
Sbjct: 2186 AGLDCEEIEKALELMSLVPKRCNDMMNLGRLQGYEGKLTSQGKLLQQETFCVWEQD---G 2242
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEV 640
+FL+E+ ++F + K S N Y FK+ + +S + + +SV+GD KF +
Sbjct: 2243 GVLSRSKERRVFLFEQIVIFSELLRKGSSNPG-YQFKNSIKVSYLAMQDSVEGDPCKFVL 2301
Query: 641 WRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
W +G E T+ A + VK WV+ I +LLD
Sbjct: 2302 WSRGSAERFTLQASSAGVKMTWVDTI-AILLD 2332
Score = 57.2 bits (132), Expect = 2e-06
Identities = 48/143 (33%), Positives = 72/143 (50%), Gaps = 36/143 (25%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLK----------DLERC----------ISATE- 440
+PP LV + D++FGN+ +++ FH +FLK D+ C ++AT+
Sbjct: 1303 VPPGLVNKDDIVFGNIQDIYEFHNSIFLKELENYEQLPEDVGHCFVTWVTAHPAVTATQS 1362
Query: 441 --------LVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHL--FLQACQLRLGH 490
L + FV + + F +Y YC+N P S L+ H F + Q R G
Sbjct: 1363 LLSLVKALLSSSSFVCQADKF-HMYVTYCRNKPDSS----LLIQQHGVGFFEEVQRRHGL 1417
Query: 491 KLPLAAYLLKPVQRITKYQLLLK 513
+++ L+KPVQRITKYQLLLK
Sbjct: 1418 ANSVSSALIKPVQRITKYQLLLK 1440
Score = 41.5 bits (93), Expect = 0.080
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 19/103 (18%)
Query: 553 GVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKA 612
G+ L QGELL+Q SFLV H+FL+E +++F K K+S +
Sbjct: 1551 GLEEGLEVQGELLLQDSFLVWEPKSLIRKGRDR----HLFLFELSLIFSKEI-KDSSGRT 1605
Query: 613 TYHFKHDLLM--------------SQIGLTESVKGDLRKFEVW 641
Y +K L + S++G+TE ++GD KF +W
Sbjct: 1606 KYLYKSRLRVQPSLLTLSASIFQTSELGVTEHIEGDPCKFALW 1648
>UniRef50_A7RXC9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1529
Score = 171 bits (417), Expect = 4e-41
Identities = 99/272 (36%), Positives = 153/272 (56%), Gaps = 12/272 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P LVG+ ++FGN+ +++ FH + FL+++E+ + E V F+E ETF R Y YC
Sbjct: 1265 VPAGLVGKESIIFGNIQDIYKFHSNTFLQEMEKYETHPEDVGEAFIEWGETFVRFYVSYC 1324
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S L + F Q GH L ++AYL+KPVQRITKYQLLLKDLL + C
Sbjct: 1325 KNKPFSNSL--LIEHGGNFFSDLQASYGHGLSISAYLIKPVQRITKYQLLLKDLL--TCC 1380
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
LQ LD ML V + ND+M+ + G+ +L G +++Q +F V
Sbjct: 1381 EGSENSLQAGLDVMLSVPRRANDAMYVNMLHGLEENLDHLGRIILQDAFTVFDPK----L 1436
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E+A++F K TK++ K +Y +K+ L S++G+TE + D KF VW
Sbjct: 1437 LRRKGKDRHVFLFEQALVFSK-ETKDNDGKVSYLYKYKLKTSELGVTEHIAEDPCKFAVW 1495
Query: 642 --RQGRCE-VHTITAPTVEVKRAWVERIKRVL 670
+ + E I A +EVK+ WV+ ++ ++
Sbjct: 1496 TGKPPQSEDKRVIKAANIEVKQLWVKELRELI 1527
>UniRef50_O60229 Cluster: Kalirin; n=25; Eumetazoa|Rep: Kalirin - Homo
sapiens (Human)
Length = 1663
Score = 171 bits (417), Expect = 4e-41
Identities = 103/281 (36%), Positives = 158/281 (56%), Gaps = 13/281 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP ++ + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1318 IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1376
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L F Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1377 KNKPDSNQL--ILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1434
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G L+ L+ ML V K ND+MH + G +L QGEL++Q +F V
Sbjct: 1435 GK--GELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPK----S 1488
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S Y +K+ LL S++G+TE V+GD KF +W
Sbjct: 1489 LIRKGRERHLFLFEISLVFSK-EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALW 1547
Query: 642 --RQGRCEVHTI-TAPTVEVKRAWVERIKRVLLDQLKELKG 679
R + T+ A +E K+ W++ I+ V+ +++ LKG
Sbjct: 1548 SGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKG 1588
>UniRef50_Q4RY59 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14978, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1113
Score = 168 bits (409), Expect = 4e-40
Identities = 87/169 (51%), Positives = 110/169 (65%), Gaps = 2/169 (1%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HL+P +L + D+LFGN+ E++ FH+ FLK+LE ELV CF+
Sbjct: 587 GYAAEMDNPAMAHLIPNSLQNKKDILFGNMSEIYQFHKRTFLKELEAYTDCPELVGRCFL 646
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ + ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 647 ERMKDL-QIYEAYCQNKPRSESLWRQCSDC-AFFQECQKKLEHKLGLDSYLLKPVQRITK 704
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPV 556
YQLLLK+LL+YS LQ+AL +L +LK VNDSMH IAITG V
Sbjct: 705 YQLLLKELLKYSRGCEGCDDLQEALTSILGILKAVNDSMHLIAITGYEV 753
Score = 111 bits (267), Expect = 7e-23
Identities = 59/127 (46%), Positives = 79/127 (62%), Gaps = 8/127 (6%)
Query: 557 DLSQQGELLMQGSFLVVSENKXXXXXXXXXXXX-----HIFLYEKAMLFCKPATKNS--H 609
+LS+ G LLMQGSF V +E+K H+FL+EKA+LFCK +N +
Sbjct: 792 NLSELGRLLMQGSFSVWTEHKKGHAKVKDLARFKPMQRHLFLHEKALLFCKRREENGEGY 851
Query: 610 NKA-TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKR 668
KA +Y FKH L MS +G+TE+ KGD +KFE+W R EV + APT E+K AWV I++
Sbjct: 852 EKAPSYSFKHSLSMSAVGITENAKGDNKKFEIWCNSRDEVFIVQAPTTEIKSAWVNEIRK 911
Query: 669 VLLDQLK 675
VL QL+
Sbjct: 912 VLTQQLQ 918
>UniRef50_O75962 Cluster: Triple functional domain protein; n=71;
Eumetazoa|Rep: Triple functional domain protein - Homo
sapiens (Human)
Length = 3038
Score = 167 bits (405), Expect = 1e-39
Identities = 101/282 (35%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP +V + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1270 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1328
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1329 KNKPDSTQL--ILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1386
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1387 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1440
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S ++ Y +K L S++G+TE V+GD KF +W
Sbjct: 1441 LIRKGRERHLFLFEMSLVFSK-EVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALW 1499
Query: 642 RQGRCEVH----TITAPTVEVKRAWVERIKRVLLDQLKELKG 679
GR + A ++E K+ W++ I+ V+ ++ LKG
Sbjct: 1500 -VGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKG 1540
Score = 163 bits (397), Expect = 1e-38
Identities = 95/276 (34%), Positives = 159/276 (57%), Gaps = 10/276 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 1945 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 2003
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 2004 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 2061
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
S+ T+ L++A++ M +V + ND M+ + G + QG+LL+Q +FLV ++
Sbjct: 2062 ASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQD---A 2118
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
IFL+E+ ++F +P K + + FK+ + +S + L E+V+ D KF
Sbjct: 2119 GLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFA 2178
Query: 640 VW-RQGR-CEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ R G E + + + V++ W+ I ++L +Q
Sbjct: 2179 LTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQ 2214
>UniRef50_UPI0000D5595A Cluster: PREDICTED: similar to CG18214-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG18214-PA, isoform A - Tribolium castaneum
Length = 1611
Score = 165 bits (401), Expect = 4e-39
Identities = 101/274 (36%), Positives = 157/274 (57%), Gaps = 19/274 (6%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQ 462
P + G+ +++FGN+ E++ FH +FLK+LE+ + E V CFV + F +Y +YC+
Sbjct: 1278 PAAIHGKDEIIFGNIEEIYNFHNSIFLKELEKYETMPEDVGHCFVTWAQK-FDIYVHYCK 1336
Query: 463 NIPRSERLRETLVDTHLFLQACQLRLGHKL--PLAAYLLKPVQRITKYQLLLKDLLRYSE 520
N P S +L+ H +L+ HK+ P+AAYL+KPVQRITKYQLLLKDL S
Sbjct: 1337 NKPES----NSLLVQHGGGYFEELQKKHKVEHPIAAYLIKPVQRITKYQLLLKDL--QSC 1390
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
C ++ L+ ML V K ND+MH + G V ++ GE+++Q +F V +
Sbjct: 1391 CNEGQGEIKDGLEVMLNVPKKANDAMHLSLVEGCDVSANKLGEVVLQDAFSVWDPKQ--- 1447
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEV 640
HIFL+E +LF K K+S K Y +K+ L+ S++G+TE ++GD KF V
Sbjct: 1448 -LIRKGRERHIFLFELYLLFTK-EVKDSAGKVKYIYKNKLMTSELGVTEHMEGDECKFAV 1505
Query: 641 WRQGRCEVH----TITAPTVEVKRAWVERIKRVL 670
W GR + + A ++E K+ WV++++ V+
Sbjct: 1506 W-TGRAPISDYRIVLRASSLETKQLWVKKLREVI 1538
>UniRef50_UPI000065F2B5 Cluster: Huntingtin-associated
protein-interacting protein (Protein Duo).; n=2;
Euteleostomi|Rep: Huntingtin-associated
protein-interacting protein (Protein Duo). - Takifugu
rubripes
Length = 2988
Score = 165 bits (401), Expect = 4e-39
Identities = 96/301 (31%), Positives = 166/301 (55%), Gaps = 13/301 (4%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
++ G+ + IE+ +P + G+ ++FGN+H+++ +H++ F+ +LE+C+ E +
Sbjct: 2005 IVVEGFMKRIEEKG----VPDDMKGKDKIVFGNIHQIYDWHREFFVGELEKCLDDHEHLP 2060
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F+ K E +Y YCQN P+SE + + + + Q + +L ++ +L+KP+Q
Sbjct: 2061 ELFI-KHERRLHMYVIYCQNKPKSEFI---VAEYDTYFDGIQQDIQSRLTISDFLIKPIQ 2116
Query: 504 RITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
RITKYQLLLKD L++S + G +++A+D M V K ND M+ + G L+ QG
Sbjct: 2117 RITKYQLLLKDFLKFSSKAGMDCEQIEKAVDLMSQVPKLCNDMMNLGRLQGYEGKLTSQG 2176
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+LL Q +F V ++ +FL+E+ ++F + K S Y FK + +
Sbjct: 2177 KLLQQETFFVTEQD---AGVLSRSKERRVFLFEQIVIFSELLRKGSSTPG-YQFKKSIKV 2232
Query: 623 SQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERV 682
S +GL +SV D KF + +G E T+ A V++K+ WV I+ +L DQ K L GE+
Sbjct: 2233 SYLGLEDSVDNDPCKFVLSCRGSSERFTLQAANVDIKQVWVRHIQVLLDDQNKFLYGEKT 2292
Query: 683 R 683
+
Sbjct: 2293 Q 2293
Score = 88.2 bits (209), Expect = 7e-16
Identities = 72/283 (25%), Positives = 133/283 (46%), Gaps = 23/283 (8%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP + + ++FGN+ +++ FH ++FLK+L E V CFV ++
Sbjct: 1348 IPPGIANKEHIIFGNMQDIYDFHNNIFLKELINYEQLPEDVGHCFVTWVSVSINSGYFFI 1407
Query: 462 QNIPRS--ERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ + H+++ C+ + P ++ L+ Q T + LL S
Sbjct: 1408 LMVVNTYPSTFFPQADKFHIYVDYCKNK-----PDSSQLILE-QAGTFFDELL------S 1455
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
C ++ LD +L S+ + +G +L QGEL++Q SF V
Sbjct: 1456 CCEEGKGEIKDGLDLVLTSHLSFFFSLSSLP-SGFEENLEVQGELILQDSFQVWDPRSLI 1514
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+E +++F K K+S + Y +K+ LL S++G+TE ++GD KF
Sbjct: 1515 RKGRDR----HLFLFEFSLVFSKEI-KDSAGRTKYQYKNRLLTSELGVTEHIEGDPCKFA 1569
Query: 640 VW--RQGRCEVHTI-TAPTVEVKRAWVERIKRVLLDQLKELKG 679
+W R + T+ A ++E K+ W++ I+ V+ +++ LKG
Sbjct: 1570 LWAGRTPSSDNKTVLKATSMEAKQEWIKNIREVIQERMTHLKG 1612
>UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet;
n=20; Mammalia|Rep: Serine/threonine-protein kinase Duet
- Homo sapiens (Human)
Length = 1289
Score = 164 bits (398), Expect = 9e-39
Identities = 94/291 (32%), Positives = 162/291 (55%), Gaps = 13/291 (4%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
++ G+ + IE+ +P + G+ ++FGN+H+++ +H+D FL +LE+CI + +A
Sbjct: 253 IVVEGFMKRIEEKG----VPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLA 308
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F+ K E +Y +YCQN PRSE + + + + + + + +L L+ +L+KP+Q
Sbjct: 309 QLFI-KHERKLHIYVWYCQNKPRSEYI---VAEYDAYFEEVKQEINQRLTLSDFLIKPIQ 364
Query: 504 RITKYQLLLKDLLRYSE-CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
RITKYQLLLKD LRYSE G + +++A++ M +V K ND M+ + G L+ QG
Sbjct: 365 RITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQG 424
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+LL Q +F V+ + +FL+E+ ++F + K S Y FK + M
Sbjct: 425 KLLQQDTFYVI---ELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPG-YMFKRSIKM 480
Query: 623 SQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ + L E+V D KF + + E + A ++++AWV+ I +VL Q
Sbjct: 481 NYLVLEENVDNDPCKFALMNRETSERVVLQAANADIQQAWVQDINQVLETQ 531
>UniRef50_Q7KY09 Cluster: Trio; n=10; Diptera|Rep: Trio - Drosophila
melanogaster (Fruit fly)
Length = 2263
Score = 163 bits (397), Expect = 1e-38
Identities = 101/275 (36%), Positives = 151/275 (54%), Gaps = 19/275 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L+GQ DV+FGN+ E+ FHQ +FL++LE+ + E V CFV F +Y +YC
Sbjct: 1319 VPSALIGQEDVIFGNIKEIHHFHQKIFLRELEKYETMPEDVGHCFVTWASK-FDMYVHYC 1377
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S L + F + Q RL PL AYL+KPVQRITKYQLLLKDLL S C
Sbjct: 1378 KNKPTSNNL--LVQHGGSFFEELQRRLEVDHPLPAYLIKPVQRITKYQLLLKDLL--SCC 1433
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
+++ L+ ML V K ND+MH + V + + GE+++Q +F +
Sbjct: 1434 EESHGEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVDKLGEVVLQDAFQAWDTKQ---- 1489
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
+FL+E +LF K ++ N Y FK L+ + +G+TE ++GD KF VW
Sbjct: 1490 IIRKGRERRVFLFELYLLFAKEVKES--NVVKYQFKSKLMTTDMGITEHIEGDETKFAVW 1547
Query: 642 RQGR------CEVHTITAPTVEVKRAWVERIKRVL 670
GR C + + A ++E K+ WV++++ V+
Sbjct: 1548 -TGRSPMLSDCRI-VLKATSLETKQIWVKKLREVM 1580
Score = 111 bits (266), Expect = 9e-23
Identities = 86/301 (28%), Positives = 154/301 (51%), Gaps = 28/301 (9%)
Query: 385 INSGYKEEIEKPENQHLLPPTLVG-QADVLFGNLHELFTFHQDVFLKDLERCI-SATELV 442
I +GY EI + +P L G + ++F N+ +++ +H+D FL+ L C S +L
Sbjct: 1963 IVNGYMTEINNTNSDIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSPADLG 2022
Query: 443 ALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHL-FLQACQLRLGHKLPLAAYLLKP 501
L +++ T F LY YC N P L E +V H + + + +LGH+L L+ ++KP
Sbjct: 2023 PL--IKRSATKFALYYTYCSNKP----LSEYIVSAHYQYFDSIRQKLGHRLDLSNLIIKP 2076
Query: 502 VQRITKYQLLLKDLLRYSECGSM---TTGLQQALDCMLVVLKCVNDSMHQI-AITGVPVD 557
VQRITKY+LL+K++++ +E + LQ+A M VV+K VND M + ++ +
Sbjct: 2077 VQRITKYELLIKEIIKATEGAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQDFDGE 2136
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK-PATKNSHNKATYHF 616
++ QG LLMQG V + +FL+++ ++F TKN + + +
Sbjct: 2137 ITAQGSLLMQGPMNCVVD------AAQKHRELQVFLFQQIIIFADIEKTKNQYASPIFKY 2190
Query: 617 KHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTIT----APTVEVKRAWVERIKRVLLD 672
+ + ++ + + E GD R F++ R ++ +T A + E W + + ++L
Sbjct: 2191 RSHIQLNHMQMKE--LGDCR-FQI-RSTDPKIPEMTIICQAASQENYAGWRDMLNKILQQ 2246
Query: 673 Q 673
Q
Sbjct: 2247 Q 2247
>UniRef50_Q1RLV0 Cluster: Zgc:136817; n=3; Danio rerio|Rep:
Zgc:136817 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 471
Score = 163 bits (395), Expect = 2e-38
Identities = 90/277 (32%), Positives = 156/277 (56%), Gaps = 9/277 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H++ FL +LE+C+ + +A F+ K E +Y YC
Sbjct: 82 VPEDMTGKDKIVFGNIHQIYDWHKEFFLCELEKCLQDHDKLAELFI-KHERRLHMYVIYC 140
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-E 520
QN PRSE + + + + + Q + +L ++ YL+KP+QRITKYQLLLKD L+YS +
Sbjct: 141 QNKPRSEFV---VAEYDKYFEGVQQEINSRLAISDYLIKPIQRITKYQLLLKDFLKYSTK 197
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G +++A++ M +V K ND M+ + G L+ QG+LL Q +F V ++
Sbjct: 198 AGLDCKEIEKAVELMSLVPKQCNDMMNLGRLQGYEGKLTAQGKLLQQDTFFVTEQD---S 254
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEV 640
+FL+E+ ++F + K S Y FK + +S + + E V+ D KF +
Sbjct: 255 GVLSRSKERRVFLFEQIVIFSELLRKGSSTPG-YQFKKSIKVSYLSMEEQVESDPYKFVL 313
Query: 641 WRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
+G E T+ A V++K+ WV+ I+ +L Q+ L
Sbjct: 314 LCRGSSERLTLQAANVDIKKEWVQSIRELLDMQINFL 350
>UniRef50_UPI000058400D Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 565
Score = 162 bits (394), Expect = 3e-38
Identities = 104/290 (35%), Positives = 155/290 (53%), Gaps = 19/290 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L G+ ++FGNL +++ FH VFL++L+ C++ V CF++ R+ F LY+ Y
Sbjct: 78 IPQALRGKRSIVFGNLEKIYHFHSRVFLRELKGCMTTPLQVGQCFLKHRQE-FGLYALYN 136
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
N PRS+ L L D F ++ Q RL + LA+YLLKPVQR+ KY LLL+DL+R
Sbjct: 137 MNKPRSDSL---LADFGHFFRSKQRRLKDSMDLASYLLKPVQRLGKYALLLRDLIRQCGT 193
Query: 522 GSMTTGLQQALDCML-VVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
+A + M+ ++ ND + ++ V+L +QGEL+ Q FLV
Sbjct: 194 EDQEQNHLRAAEVMIEFQMRHGNDLLAMDSLQDCDVNLREQGELIRQAEFLV-------- 245
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEV 640
H+FL+E +LF KP K S Y +K L MS IGLTES+ K EV
Sbjct: 246 YRGIRKCVRHVFLFEDLILFSKP-KKTSKGHDVYQYKFSLKMSDIGLTESIGETGTKLEV 304
Query: 641 W---RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGL 687
W R+ + +T+ A + ++KR W I R+L Q L+ + RQ+ L
Sbjct: 305 WFRRRKSTDKAYTMQARSPQIKRVWTTEISRLLWHQ--ALRSKETRQHEL 352
>UniRef50_UPI0000F211CF Cluster: PREDICTED: similar to RAC/CDC42
exchange factor; n=3; Danio rerio|Rep: PREDICTED:
similar to RAC/CDC42 exchange factor - Danio rerio
Length = 749
Score = 154 bits (374), Expect = 7e-36
Identities = 86/277 (31%), Positives = 153/277 (55%), Gaps = 11/277 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C++ E +A F+ K E +Y YC
Sbjct: 362 IPEDMKGKDKIVFGNIHQIYDWHKDYFLAELEKCVAEPERLAQLFI-KHERRLHMYVVYC 420
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN P+SE + ++T + + + +LGH+L L L+KPVQRI KYQLLLKD + Y++
Sbjct: 421 QNKPKSEHIVSEYIET--YFEELKQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFHKYYTK 478
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L++A++ M V K ND M+ + G ++ QG+LL Q +F + ++
Sbjct: 479 AGMDTEELEKAVEVMCFVPKRCNDMMNVGRLQGFEGKITAQGKLLQQDTFTITEQD---S 535
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
+FL+E+ ++F +P K + Y FK+ + +S +G+ V GD +F
Sbjct: 536 SILSRAKERRVFLFEQLVIFSEPIDRKKGFSLPGYIFKNSIKISCLGVEACVDGDPNRFA 595
Query: 640 VWRQ---GRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ + G + + + + + AWV + ++L Q
Sbjct: 596 LTSRGADGSTVRYVLYSSSPNICMAWVSDVSQILETQ 632
>UniRef50_Q6DN89 Cluster: Quattro; n=2; Eumetazoa|Rep: Quattro - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1989
Score = 154 bits (373), Expect = 1e-35
Identities = 102/291 (35%), Positives = 155/291 (53%), Gaps = 22/291 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+E+P+ +P L GQ ++FGNL +L FHQ F+++LE C+ V CF++
Sbjct: 1531 YMPELERPD----VPQDLRGQRGLIFGNLEKLRDFHQHHFIQELELCLEKPFSVGRCFLK 1586
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
+E+F LY+ Y +N PRSE L + F + Q +L L L++YLLKPVQRI+KY
Sbjct: 1587 HKESF-GLYALYSKNKPRSENL--LIQHGKDFFKQKQQQLKDALDLSSYLLKPVQRISKY 1643
Query: 509 QLLLKDLLRYSECGS----MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGEL 564
LLL+DLLR EC + T + AL+ + L+ N+ + I G V+L +QG+L
Sbjct: 1644 SLLLQDLLRECECVTNAELQRTEIHTALNIIQFQLRHGNNLLAMDDIYGCDVNLKEQGQL 1703
Query: 565 LMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQ 624
+ Q FL+ K HIFL++ +LF K K TY +K S
Sbjct: 1704 IRQDEFLLTFRKK--------KCYRHIFLFQDLILFSK-TRKTDIGNDTYIYKQSFKTSD 1754
Query: 625 IGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
IG+T + FE+W R+ + + + A + EVK +W ++R+L +Q
Sbjct: 1755 IGMTHNSGDSGLCFEIWFRRRKTQDTYVLQAASREVKESWTRDLERILWEQ 1805
>UniRef50_Q96PX9 Cluster: KIAA1909 protein; n=12; Euteleostomi|Rep:
KIAA1909 protein - Homo sapiens (Human)
Length = 1287
Score = 154 bits (373), Expect = 1e-35
Identities = 105/313 (33%), Positives = 164/313 (52%), Gaps = 25/313 (7%)
Query: 380 QCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT 439
+C + Y E+E+ + LP L G+ V+FGNL +L FHQ FL++LERC
Sbjct: 838 RCLGYVIDNYFPEMERMD----LPQGLRGKHHVIFGNLEKLHDFHQQHFLRELERCQHCP 893
Query: 440 ELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLL 499
V F+ E F +Y Y +N P+S+ L + + F + Q LG K+ LA+YLL
Sbjct: 894 LAVGRSFLRHEEQF-GMYVIYSKNKPQSDALLSS--HGNAFFKDKQRELGDKMDLASYLL 950
Query: 500 KPVQRITKYQLLLKDLLRYSECG---SMTTGLQQALDCMLVV-LKCVNDSMHQIAITGVP 555
+PVQR+ KY LLL+DLL+ + CG G +A + ++ L+ ND + AI G
Sbjct: 951 RPVQRVAKYALLLQDLLKEASCGLAQGQELGELRAAEVVVCFQLRHGNDLLAMDAIRGCD 1010
Query: 556 VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK-PATKNSHNKATY 614
V+L +QG+L + F+V K H+FL+E +LF K + SH+ Y
Sbjct: 1011 VNLKEQGQLRCRDEFIVCCGRK--------KYLRHVFLFEDLILFSKTQKVEGSHD--VY 1060
Query: 615 HFKHDLLMSQIGLTESVKGDLRKFEVW---RQGRCEVHTITAPTVEVKRAWVERIKRVLL 671
+K ++IG+TE+V +FE+W RQ + + + A + EVK AW + I R+L
Sbjct: 1061 LYKQSFKTAEIGMTENVGDSGLRFEIWFRRRQKSQDTYILQASSAEVKSAWTDVIGRILW 1120
Query: 672 DQLKELKGERVRQ 684
Q + + R+++
Sbjct: 1121 RQALKSRELRIQE 1133
>UniRef50_UPI0000F1E6F8 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1671
Score = 153 bits (371), Expect = 2e-35
Identities = 103/307 (33%), Positives = 163/307 (53%), Gaps = 25/307 (8%)
Query: 385 INSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVAL 444
I Y E+E+ + LP L G+ V+FGNL +L FH FLK+LE C + V+
Sbjct: 1189 IIDNYFPEMERAD----LPQDLRGKRSVIFGNLEKLVDFHSQYFLKELESCCNHPLRVSH 1244
Query: 445 CFVEKRETFFRLYSYYCQNIPRSERLRETLVDTH--LFLQACQLRLGHKLPLAAYLLKPV 502
CF+ ++ F LY+ Y +N P+S+ TL+ +H F + Q+ LG K+ LA+YLLKP+
Sbjct: 1245 CFLRHQDQF-SLYALYSKNKPKSD----TLLASHGNNFFKHKQMELGDKMDLASYLLKPI 1299
Query: 503 QRITKYQLLLKDLLR-YSECGSM-TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ 560
QR++KY LLLKDL++ SE T L+ A + + L+ ND + AI V+L +
Sbjct: 1300 QRMSKYALLLKDLIKEVSEVQEQELTYLRAAAEMVKFQLRHGNDLLAMDAIRDCDVNLKE 1359
Query: 561 QGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDL 620
QG+L+ Q F + K H+FL+E +LF KP + Y +KH
Sbjct: 1360 QGQLVRQDEFTISYGRK--------KCQRHVFLFEDLVLFSKP-KRIEGGLDVYIYKHSF 1410
Query: 621 LMSQIGLTESVKGDLRKFEVW---RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
+ +G+TE+ + +FE+W R + + + + + T ++K AW I R+L Q
Sbjct: 1411 KTADVGMTETSGENSLRFEIWFRRRTSKNQTYILQSSTADIKHAWTCDIARILWQQATRN 1470
Query: 678 KGERVRQ 684
K R+++
Sbjct: 1471 KEIRMQE 1477
>UniRef50_UPI0000F1E2DD Cluster: PREDICTED: similar to RAC/CDC42
exchange factor; n=3; Danio rerio|Rep: PREDICTED:
similar to RAC/CDC42 exchange factor - Danio rerio
Length = 640
Score = 149 bits (360), Expect = 4e-34
Identities = 87/277 (31%), Positives = 153/277 (55%), Gaps = 11/277 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L G+ ++FGN+H+++ +H+D FL +LE+C+S +L+A F+ K E +Y YC
Sbjct: 305 VPEYLEGKDKIVFGNIHQIYDWHKDYFLGELEKCVSEPDLLAQLFI-KHERRLNMYVVYC 363
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN+P+SE + ++T + + + +LGH+L L L+KPVQRI KYQLLLKD L+ Y++
Sbjct: 364 QNMPKSEHIVSEYIET--YFEDLRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYTK 421
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L++A++ M V K ND M+ + G L QG+LL Q +F + EN+
Sbjct: 422 AGRQTEDLERAVEVMCFVPKRCNDMMNVGRLQGFEGQLRAQGKLLQQDTFTFI-ENE--N 478
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
+FL+E+ ++ +P K + Y +K+ + +S + + + D +
Sbjct: 479 SILSRPKERRVFLFEQLIILSEPMDRKRGFSLPGYVYKNSIKISCLSIEDRCPEDPCRLV 538
Query: 640 VWRQ---GRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ + G + + A + E++ +W I ++L Q
Sbjct: 539 LTSRNIDGSLQKFILRASSSEIRTSWANDIIQMLETQ 575
>UniRef50_UPI00004D56CF Cluster: Puratrophin-1 (Pleckstrin homology
domain-containing family G member 4) (Purkinje cell
atrophy-associated protein 1).; n=1; Xenopus
tropicalis|Rep: Puratrophin-1 (Pleckstrin homology
domain-containing family G member 4) (Purkinje cell
atrophy-associated protein 1). - Xenopus tropicalis
Length = 1025
Score = 148 bits (359), Expect = 5e-34
Identities = 101/304 (33%), Positives = 156/304 (51%), Gaps = 20/304 (6%)
Query: 385 INSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVAL 444
I+ Y E+E+ + LP L G+ ++FGNL +L FH FLK+LE C + V+
Sbjct: 586 ISENYFPEMERVD----LPQDLRGKRGIIFGNLEKLRDFHSQYFLKELESCCNHPLRVSH 641
Query: 445 CFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQR 504
CF+ ++ F +Y+ Y +N PRS+ L + ++F + Q LG K+ LA+YLLKP+QR
Sbjct: 642 CFLRHKDQF-GMYALYSKNKPRSDALLGS--HGNIFFKNKQCLLGDKMDLASYLLKPIQR 698
Query: 505 ITKYQLLLKDLLRYSECG--SMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
++KY LLLKDL++ E L+ A + + L+ ND + AI V+L +QG
Sbjct: 699 MSKYALLLKDLIKECEEAQEQELAYLRAAEEMVKFQLRHGNDLLAMDAIRDCDVNLKEQG 758
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+L+ Q F V K H+FL+E +LF KP + Y +K
Sbjct: 759 QLVRQDEFTVWLGRK--------KCQRHVFLFEDLILFSKP-KRIEGGLDVYIYKRSFKT 809
Query: 623 SQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGE 680
+ IGLTE+ +FE+W R+ + H + A E K AW I ++L Q K
Sbjct: 810 ADIGLTENSGDSGLRFEIWFRRRKSSDTHILQASNPETKHAWTSDIAKILWQQATRNKEI 869
Query: 681 RVRQ 684
R+++
Sbjct: 870 RMQE 873
>UniRef50_UPI000065D244 Cluster: Triple functional domain protein (EC
2.7.11.1) (PTPRF-interacting protein).; n=1; Takifugu
rubripes|Rep: Triple functional domain protein (EC
2.7.11.1) (PTPRF-interacting protein). - Takifugu
rubripes
Length = 3108
Score = 147 bits (357), Expect = 8e-34
Identities = 91/295 (30%), Positives = 160/295 (54%), Gaps = 14/295 (4%)
Query: 383 SLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELV 442
SL+ GY + + +P + G+ +FGN+++++ +H+D+FL +LE+C+ ++ +
Sbjct: 2021 SLVVEGYMSRMREQG----IPDDMKGKDKTVFGNINQIYDWHRDIFLGELEKCLEDSDQL 2076
Query: 443 ALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPV 502
F+ K E +Y YCQN P+SE + +DT+ QLR HKL ++ L+KPV
Sbjct: 2077 GPLFL-KHERKLNMYVVYCQNKPKSEHIVSEYIDTYFEDMRQQLR--HKLQISDLLIKPV 2133
Query: 503 QRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
QRI KYQLLLKD L++S + G + L++A++ M +V K ND M+ + G + Q
Sbjct: 2134 QRIMKYQLLLKDFLKHSKKAGLESVELEKAVEVMCIVPKRCNDMMNVGRLQGFDGKIVAQ 2193
Query: 562 GELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKP-ATKNSHNKATYHFKHDL 620
G LL+Q +F+V + +FL+E+ ++F +P K + + +K+ +
Sbjct: 2194 GRLLLQDTFMV---SDPEGGHLGRMKERRVFLFEQLVIFSEPLEKKKGFSLPGFLYKNSI 2250
Query: 621 LMSQIGLTESVKGDLRKFEVWRQ--GRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+S +GL E+V+GD KF + + E + + V+ W +I ++L Q
Sbjct: 2251 KISCLGLEENVEGDPCKFILTSRAANASESFVLHSSHPGVREVWTLQISQILESQ 2305
Score = 131 bits (317), Expect = 6e-29
Identities = 79/222 (35%), Positives = 123/222 (55%), Gaps = 10/222 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP ++ + ++FGN+ +L+ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1387 IPPGVINKEHIIFGNMQDLYEFHHNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVNYC 1445
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1446 KNKPDSTQL--ILEHAGNYFDEIQQRHRLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1503
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1504 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1557
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMS 623
H+FL+E +++F K K+S+ ++ Y +K L +S
Sbjct: 1558 LIRKGRERHLFLFEMSLIFSK-EVKDSNGRSKYIYKSKLFVS 1598
>UniRef50_Q86YR7 Cluster: Rho family guanine-nucleotide exchange
factor; n=10; Eutheria|Rep: Rho family
guanine-nucleotide exchange factor - Homo sapiens
(Human)
Length = 1031
Score = 147 bits (356), Expect = 1e-33
Identities = 100/337 (29%), Positives = 168/337 (49%), Gaps = 32/337 (9%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
I + S+I+ GY ++ +HL+P L D LFGN+ EL+ FH FLK+LE+C
Sbjct: 552 IKEIKSIID-GYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAE 610
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
EL+A CF++++E ++Y Y +N+PR+ + + D F CQ +L H LPL Y
Sbjct: 611 NPELLAHCFLKRKED-LQIYFKYHKNLPRARAIWQECQDCAYF-GVCQRQLDHNLPLFKY 668
Query: 498 LLKPVQRITKYQLLLKDLLRY----------SECG-------------SMTTGLQQALDC 534
L P QR+ KYQ+LLK LL + E G + +T LQQAL
Sbjct: 669 LKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELGGSAKDGPKRTKDSAFSTELQQALAV 728
Query: 535 MLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXX----XXXH 590
+ ++K ++ A+T P D+ + G+LL+ G F V + +K
Sbjct: 729 IEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQ 788
Query: 591 IFLYEKAMLFCKPATKNSHNKAT--YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV 648
I+L+E+ ++FCK + + Y FK + + + + + +G RKFE+ + E
Sbjct: 789 IYLFERGIVFCKIRMEPGDQGLSPHYSFKKAMKLMTLSIRQLGRGSHRKFEIASRNGLEK 848
Query: 649 HTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQY 685
+ + A + E++ W I ++L++Q +K + Q+
Sbjct: 849 YILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQF 885
>UniRef50_O02133 Cluster: Temporarily assigned gene name protein
150, isoform b; n=3; Caenorhabditis|Rep: Temporarily
assigned gene name protein 150, isoform b -
Caenorhabditis elegans
Length = 638
Score = 147 bits (355), Expect = 1e-33
Identities = 86/284 (30%), Positives = 141/284 (49%), Gaps = 10/284 (3%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E E ENQ+ LP TL G+ D LFGN+ EL+ FH L+DL S E+ + ++
Sbjct: 267 YLEPFEATENQNSLPDTLRGKPDCLFGNVRELYKFHHRTVLEDLVAARSTAEMCRV-LMQ 325
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R + Y YCQ ++++R++ V H F + CQ H + +++YLLKP+QRI KY
Sbjct: 326 HRNQIYVTYRTYCQIHGSNQKVRDS-VKNHPFFKECQRNANHNMDMSSYLLKPIQRIMKY 384
Query: 509 QLLLKDLLRYSEC-GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
QLLL +++ +C + + D M+ +L ++ SM Q+ I+G DL G L +Q
Sbjct: 385 QLLLGNIM--DDCPADVRDEVAMTRDSMVELLNQIDASMQQLHISGYNGDLKSLGLLRLQ 442
Query: 568 GSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKN---SHNKATYHFKHDLLMS- 623
V + N+ IF ++ A++FCK N + N +F+H +
Sbjct: 443 TECDVFTYNRKKKAKLSRAQKRFIFFFDGAVMFCKKRVSNPGTTLNSEPEYFEHKFCIPI 502
Query: 624 -QIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERI 666
+G S + +FEVW + + + I + W++R+
Sbjct: 503 ISLGYDTSSRTGASRFEVWDDAKTDAYVIETIDQTARTKWIQRL 546
>UniRef50_Q86VW2 Cluster: RhoA/RAC/CDC42 exchange factor; n=52;
Tetrapoda|Rep: RhoA/RAC/CDC42 exchange factor - Homo
sapiens (Human)
Length = 580
Score = 146 bits (353), Expect = 3e-33
Identities = 92/303 (30%), Positives = 163/303 (53%), Gaps = 13/303 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L G+ ++FGN+ +++ +H+D FL++L+RC+ + +A F+ K E +Y Y
Sbjct: 195 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFI-KHERRLHMYVVYY 253
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN P+SE + D+ + + + +LGH+L L L+KPVQRI KYQLLLKD L+ Y+
Sbjct: 254 QNKPKSEHVVSEFGDS--YFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNR 311
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L+QA++ M V K ND M + G L+ QG+LL Q +F V+E +
Sbjct: 312 AGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFW-VTEPEAGG 370
Query: 581 XXXXXXXXXHIFLYEKAMLFCKP--ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+FL+E+ ++F + + Y +K+ + +S +GL +++GD +F
Sbjct: 371 LLSSRGRERRVFLFEQIIIFSEALGGRVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRF 430
Query: 639 EVWR---QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTLIQ 695
+ +G + + + A + +AW++ + ++L Q L Q +++ R Q
Sbjct: 431 ALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFL---NALQSPIEYQRRESQ 487
Query: 696 TSS 698
T+S
Sbjct: 488 TNS 490
>UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio
"Quattro.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Quattro. - Takifugu rubripes
Length = 1628
Score = 145 bits (352), Expect = 3e-33
Identities = 100/293 (34%), Positives = 155/293 (52%), Gaps = 21/293 (7%)
Query: 388 GYKEEIEKPENQHL-LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCF 446
GY + PE + +P L GQ ++FGNL +L FHQ FL +LE C++ V C
Sbjct: 1305 GYVRDHYFPELERADVPQDLRGQRGIIFGNLEKLHDFHQHHFLSELEGCVNEPFRVGRCV 1364
Query: 447 VEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRIT 506
+ E+F LY+ Y +N P+S+ L + F + QL+LG K+ L +YLLKPVQRI+
Sbjct: 1365 LRHVESF-ALYALYSKNKPQSDAL--FISHGQSFFKQKQLKLGDKMDLWSYLLKPVQRIS 1421
Query: 507 KYQLLLKDLLRYSECG----SMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
KY LLL+D++ ++CG ++ AL+ + L+ N+ + AI V+L +QG
Sbjct: 1422 KYSLLLQDMM--ADCGPGQSREMAEVKAALEVIHFQLRHGNNLLAMDAIQHCDVNLKEQG 1479
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+L+ Q FLV K HIFL+++ +LF K K TY +K
Sbjct: 1480 QLIRQDEFLVTFRKK--------KCFRHIFLFQELILFSK-TRKTEVGNDTYIYKQSFKT 1530
Query: 623 SQIGLTESVKGDLRKFEVWRQGR--CEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ IGLT++ FE+W + R + +T+ A + VK AW ++R+L +Q
Sbjct: 1531 TDIGLTQNSGDTGLCFEIWFRKRKTQDTYTLQAVSRAVKEAWTRDLERILWEQ 1583
>UniRef50_UPI00015B51B1 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1155
Score = 144 bits (349), Expect = 8e-33
Identities = 91/287 (31%), Positives = 149/287 (51%), Gaps = 17/287 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L GQ +V+FGN+ +++ FH FL++LE+C + +V CF+ + F+ LY+ Y
Sbjct: 694 IPQSLRGQRNVIFGNVEKIYEFHSQYFLRELEQCEQSPMMVGQCFLRHEKKFY-LYALYN 752
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE- 520
+N P S+ L F +A Q+ LG K+ LA+YLLKPVQR+ KY LLL+ L++
Sbjct: 753 KNKPNSDSLMAEYGTA--FFKAKQMELGDKMDLASYLLKPVQRMGKYALLLQQLVKAGTD 810
Query: 521 -CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
++ L+ A + L+ ND + ++ V++ +QG LL Q FLV
Sbjct: 811 LSEQLSADLRAAEQMVRFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFLV------- 863
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPAT-KNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+FL+E +LF K + N Y +KH + + IGLT + KF
Sbjct: 864 WQGKGKKCLRQVFLFEDLILFSKARRFPDRKNLDIYIYKHSIKTTDIGLTAVIADSPTKF 923
Query: 639 EVWRQGR--CEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
E+W + R + +T+ + ++K+AW E + +L Q L+ VR
Sbjct: 924 EIWFRKRKPGDTYTLQCASEDIKKAWTEELSNLLWKQ--ALRNREVR 968
>UniRef50_UPI0000F21533 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1652
Score = 143 bits (347), Expect = 1e-32
Identities = 92/287 (32%), Positives = 151/287 (52%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L GQ +FGNL +L+ FH F ++L+ C + CF+ RE+F LY+ Y
Sbjct: 1209 VPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESF-GLYALYS 1267
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR--YS 519
+N P+S+ L+ H + + QL LG + L++YLLKPVQRI+KY LLL+++L S
Sbjct: 1268 KNKPQSD----ALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVS 1323
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
+ +Q AL+ + L+ ND + AI ++L++QG+L+ Q F V+ K
Sbjct: 1324 DQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKK-- 1381
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
+FL++ +LF K KN Y +K + +IG+T+S R FE
Sbjct: 1382 ------RSLRRVFLFQDVILFTK-TKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFE 1434
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ + + + A T ++K AW ++ +L +Q LK +R+
Sbjct: 1435 IWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQ--ALKSRELRR 1479
>UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n=1;
Danio rerio|Rep: UPI00015A5797 UniRef100 entry - Danio
rerio
Length = 1772
Score = 143 bits (347), Expect = 1e-32
Identities = 92/287 (32%), Positives = 151/287 (52%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L GQ +FGNL +L+ FH F ++L+ C + CF+ RE+F LY+ Y
Sbjct: 1431 VPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESF-GLYALYS 1489
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR--YS 519
+N P+S+ L+ H + + QL LG + L++YLLKPVQRI+KY LLL+++L S
Sbjct: 1490 KNKPQSD----ALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVS 1545
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
+ +Q AL+ + L+ ND + AI ++L++QG+L+ Q F V+ K
Sbjct: 1546 DQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKK-- 1603
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
+FL++ +LF K KN Y +K + +IG+T+S R FE
Sbjct: 1604 ------RSLRRVFLFQDVILFTK-TKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFE 1656
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ + + + A T ++K AW ++ +L +Q LK +R+
Sbjct: 1657 IWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQ--ALKSRELRR 1701
>UniRef50_Q58EX7 Cluster: Puratrophin-1; n=18; Eutheria|Rep:
Puratrophin-1 - Homo sapiens (Human)
Length = 1191
Score = 142 bits (343), Expect = 4e-32
Identities = 101/301 (33%), Positives = 151/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 758 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 813
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 814 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 870
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 871 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 928
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 929 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 979
Query: 626 GLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W R+ + + A ++ +K+AW I +L Q K R+
Sbjct: 980 GLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 1039
Query: 684 Q 684
+
Sbjct: 1040 E 1040
>UniRef50_UPI0000F2B983 Cluster: PREDICTED: similar to FLJ00068
protein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to FLJ00068 protein - Monodelphis domestica
Length = 1760
Score = 140 bits (339), Expect = 1e-31
Identities = 106/306 (34%), Positives = 155/306 (50%), Gaps = 26/306 (8%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+E+ + +P L GQ LFGNL +L+ FH+ FL++LE C VA F+
Sbjct: 1300 YFPELERAD----VPQVLRGQRAQLFGNLEKLWDFHRHFFLRELESCSQHPLRVAHAFLR 1355
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
RE F LY+ Y +N PRS+ L + + F + Q +LG L LA+YLLKP+QR++KY
Sbjct: 1356 HREQ-FGLYALYSKNKPRSDMLLAS--HGNAFFKDKQRQLGDHLDLASYLLKPIQRMSKY 1412
Query: 509 QLLLKDLLRYSECGSMTT--------GLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ 560
LLL++L + E G + L+ A D + L+ ND + AI G V+L +
Sbjct: 1413 ALLLQELSQTCEEGPGPSWAREPDLAALRAARDLVRFQLRHGNDLLAMDAIRGCDVNLKE 1472
Query: 561 QGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDL 620
QG+L+ Q F V S K +FL+E+ +LF K A A++ +K
Sbjct: 1473 QGQLVRQDEFTVWSGRK--------KCRRQVFLFEELVLFSK-ARHRPQGTASFIYKQSF 1523
Query: 621 LMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELK 678
S IGLTE+ +FE+W R+ + + A T E KRAW I +L Q K
Sbjct: 1524 KTSDIGLTENCGDSGLRFEIWFRRRKAGDTFVLQATTQENKRAWTADIASLLWRQAARNK 1583
Query: 679 GERVRQ 684
R+ +
Sbjct: 1584 ELRMAE 1589
>UniRef50_UPI00005A5680 Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family G (with RhoGef domain)
member 4; n=2; Canis lupus familiaris|Rep: PREDICTED:
similar to pleckstrin homology domain containing, family
G (with RhoGef domain) member 4 - Canis familiaris
Length = 1405
Score = 139 bits (336), Expect = 3e-31
Identities = 102/311 (32%), Positives = 156/311 (50%), Gaps = 23/311 (7%)
Query: 388 GYKEEIEKPENQHL-LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCF 446
GY + PE + LP L G+ ++FGNL L+ FH+ FL +LERC F
Sbjct: 953 GYVIDHYFPEMERTDLPQDLRGKHSIVFGNLENLYDFHRQHFLAELERCQHCPLAAGRGF 1012
Query: 447 VEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRIT 506
+ E F +Y+ Y +N P+S+ L + F + Q +LG K+ LA+YLLKPVQR+
Sbjct: 1013 LRHEEQF-GMYALYSKNKPQSDAL--LCSHGNAFFKDKQRQLGDKMDLASYLLKPVQRMG 1069
Query: 507 KYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVV---LKCVNDSMHQIAITGVPVDLSQQG 562
KY LLL+DL+R + C L + VV L+ ND + A+ G V+L +QG
Sbjct: 1070 KYALLLQDLVREAGRCPVPEQELSELRAAQGVVRFQLRHGNDLLAMDAVRGCDVNLKEQG 1129
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+L Q F+V K H+FL+E +LF K K TY +K
Sbjct: 1130 QLRCQDEFIVCCGRK--------KYLRHVFLFEDLILFSK-TRKVDGGYDTYTYKQSFKT 1180
Query: 623 SQIGLTESVKGDLRKFEVW---RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQL---KE 676
++IG+TE++ +FE+W R+ + + + A + EVK AW I ++L Q +E
Sbjct: 1181 AEIGMTENIGDSGLRFEIWFRRRRKSQDTYVLQASSAEVKMAWTHVIGQILWRQALRNRE 1240
Query: 677 LKGERVRQYGL 687
L+ + + G+
Sbjct: 1241 LRMQEMVSMGI 1251
>UniRef50_Q17DQ5 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1433
Score = 137 bits (331), Expect = 1e-30
Identities = 97/295 (32%), Positives = 149/295 (50%), Gaps = 21/295 (7%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L GQ +V+FGN+ + FHQ FL +LE C V F+ + E+ F LY+ Y
Sbjct: 906 IPQALRGQRNVIFGNIERICEFHQQHFLSELESCEHHPIKVGSAFL-RHESKFYLYALYN 964
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P+S+ L + F +A Q+ L K+ LA+YLLKPVQR+ KY LLL+ L++
Sbjct: 965 KNKPKSDSLMSE--NGTQFFKAKQMELNDKMDLASYLLKPVQRMGKYALLLQQLMKACSA 1022
Query: 522 GSMTTG---------LQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLV 572
TT LQ+A + + L+ ND + ++ V++ +QG LL Q FL
Sbjct: 1023 AQETTNPEILEDMEELQKAEEMVRFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFL- 1081
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPAT-KNSHNKATYHFKHDLLMSQIGLTESV 631
V E K +FL+E+ +LF K + N Y +K+ + S IGLT +
Sbjct: 1082 VWEGK-----AGKKSLRQVFLFEELVLFSKARRFPDRKNLDIYIYKNSIKTSDIGLTAHI 1136
Query: 632 KGDLRKFEVWRQGRCEVHTITAPTV--EVKRAWVERIKRVLLDQLKELKGERVRQ 684
KFE+W + R T T T+ ++K AW + I ++L Q K + R+ +
Sbjct: 1137 GDSPYKFEIWFRKRKPGDTWTLQTMSEDIKNAWTDEISKLLWKQAKRNREIRLAE 1191
>UniRef50_UPI0001554F5B Cluster: PREDICTED: similar to FLJ00068
protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to FLJ00068 protein - Ornithorhynchus anatinus
Length = 1384
Score = 136 bits (329), Expect = 2e-30
Identities = 104/324 (32%), Positives = 160/324 (49%), Gaps = 41/324 (12%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+E+P+ LP L GQ LFGNL +L FH++ FL++LE C VA F+
Sbjct: 906 YVPELERPD----LPQPLRGQRARLFGNLEKLSDFHRNFFLRELESCAQHPLRVANAFLR 961
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
RE F +Y+ Y +N P+S+ L + + F + Q +LG +L LA+YLLKP+QR++KY
Sbjct: 962 HREQF-GMYALYTKNKPKSDVLMAS--HGNAFFKKKQQQLGDRLDLASYLLKPIQRMSKY 1018
Query: 509 QLLLKDLLRYS--------------------ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
LLL++L R C LQ A D + L+ ND +
Sbjct: 1019 ALLLRELARACGEGREQGLEPEAGAGPKSVWGCKDKLATLQAAHDLVRFQLRHGNDLLAM 1078
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
AI+G V+L +QG+LL Q F + + +FL+E+ +LF KP +
Sbjct: 1079 DAISGCDVNLKEQGQLLRQDEFTIWGGRR--------KCRRRVFLFEELVLFSKPRRAPA 1130
Query: 609 HNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
+A + +K + IGLTES +FE+W R+ + + A + ++K+AW I
Sbjct: 1131 GTEA-FAYKRSFKTADIGLTESAGDSGLRFEIWFRRRKASDTFVLQAASADIKQAWTMDI 1189
Query: 667 KRVLLDQL---KELKGERVRQYGL 687
+L Q KEL+ + G+
Sbjct: 1190 SSLLWRQAVRNKELRMAEMMSMGV 1213
>UniRef50_O61528 Cluster: Guanine nucleotide exchange factor UNC-73A;
n=7; Caenorhabditis|Rep: Guanine nucleotide exchange
factor UNC-73A - Caenorhabditis elegans
Length = 2488
Score = 135 bits (326), Expect = 5e-30
Identities = 97/306 (31%), Positives = 149/306 (48%), Gaps = 14/306 (4%)
Query: 376 DTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERC 435
D + +S++ GY + K + LP LVG+ ++F N+ + FH+ FLK++E+C
Sbjct: 1823 DYVKDLTSVVE-GYIGNLNKMD----LPADLVGKDKIIFANIVNILEFHKTNFLKEIEKC 1877
Query: 436 ISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLA 495
E FV+ LY YCQN P+S+ L D F + +LGHK+ L
Sbjct: 1878 SENYEAAGAAFVKYERRLHTLYVTYCQNKPKSDYLL-AQDDFEAFFADTKAKLGHKVALC 1936
Query: 496 AYLLKPVQRITKYQLLLKDLLRYSE-CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGV 554
L+KPVQRI KYQLLLKD+L+++E T L++AL M VV K +D M +
Sbjct: 1937 DLLIKPVQRIMKYQLLLKDILKFTERAKDKTDTLKKALQVMHVVPKACDDMMQVGRLQNF 1996
Query: 555 PVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKP-ATKNSHNKAT 613
LS QG+L+ QG+ L +SE+ IFL+E++ + K T
Sbjct: 1997 DKSLSAQGKLIHQGT-LQISES--IAGNVQKPKDRRIFLFEQSAIIADHIPPKKEFGNPT 2053
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTI--TAPTVEVKRAWVERIKRVLL 671
Y FK +++++ +V D +F + + + A + E K W ++ LL
Sbjct: 2054 YIFKSQFMVNKMVFEPNVPDDPLRFVIKSSDPTQPTSFIANAQSQEEKDEWNRKMSE-LL 2112
Query: 672 DQLKEL 677
DQ K L
Sbjct: 2113 DQQKRL 2118
Score = 87.0 bits (206), Expect = 2e-15
Identities = 77/298 (25%), Positives = 135/298 (45%), Gaps = 15/298 (5%)
Query: 376 DTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERC 435
D I +N KE + +N + PTL +FGN+ ++F FH D L +L +
Sbjct: 1219 DYIKDLERCVNIYVKEFDQAAKNGTI--PTLNPLKYEIFGNIEKIFKFHNDKLLHELIKY 1276
Query: 436 ISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKL--P 493
+ E V F+ + LY+ YC N + + T D F + R G ++
Sbjct: 1277 ENQPEAVGASFIVWIDLLNELYTEYCVNKEQKNHVIAT-PDAVSFFTGIRERHGLEINNE 1335
Query: 494 LAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITG 553
+A+ L+KPVQRIT+Y+LL++ L+R C T L++A + + V + VND +H +
Sbjct: 1336 IASLLIKPVQRITRYRLLIEQLMR--SCTDKTNDLKEAYEVVCSVPRKVNDLIHYNCLDL 1393
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ + G + Q + L E + +FL++ +++F K + N
Sbjct: 1394 KDFKVDELGPFVTQDT-LTFWEPR--AYFKGRGKERQVFLFDISIVFAKRIEVSPKNIKY 1450
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVH----TITAPTVEVKRAWVERIK 667
L +S++ + E V+GD +F + R G + + A K WV++I+
Sbjct: 1451 VIKGKPLPLSEVSIVEHVEGDTCRFGL-RVGTVSSNDNRIDLKANNHHTKVKWVQKIR 1507
>UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14611, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1152
Score = 134 bits (325), Expect = 6e-30
Identities = 102/312 (32%), Positives = 158/312 (50%), Gaps = 32/312 (10%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
LP L G+ V+FGNL +L FH FLK+LE C CF+ +E F LY+ Y
Sbjct: 709 LPQDLRGKRSVVFGNLEKLLDFHSQYFLKELEACWKHPLRAPHCFLRHQEQF-GLYALYS 767
Query: 462 QNIPRSE-----------RLR-----ETLVDTHLFL-------QACQLRLGHKLPLAAYL 498
+N P+S+ R+R E D L + Q Q+ LG K+ L++YL
Sbjct: 768 KNKPKSDALLASHGTEFFRVRSASPCEGAADPILNVCLGSSGSQGKQMELGDKMDLSSYL 827
Query: 499 LKPVQRITKYQLLLKDLLR---YSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVP 555
LKPVQR++KY LLL DL++ S+ ++T LQ A + L+ ND + AI
Sbjct: 828 LKPVQRMSKYALLLTDLMKEVSSSQEAELST-LQAATSMVKFQLRHGNDLLAMDAIRECD 886
Query: 556 VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYH 615
VDL ++ ++ ++ +++ H+FL+++ +LF KP K A +
Sbjct: 887 VDLCSSLQVNLKEQGQLIRQDEFTVWTGRRRCQRHVFLFQELVLFSKP-KKMEGALAVFI 945
Query: 616 FKHDLLMSQIGLTESVKGDLRKFEVW-RQGRCEVHTI--TAPTVEVKRAWVERIKRVLLD 672
+KH + +GLTE+ + +FE+W R+ R + +T+ APT EVK AW I R+L
Sbjct: 946 YKHSFKTADVGLTETAGNNGLQFEIWFRRRRSKSNTVILQAPTEEVKNAWTADITRILWA 1005
Query: 673 QLKELKGERVRQ 684
Q K R+++
Sbjct: 1006 QATRNKELRLKE 1017
>UniRef50_Q7KU89 Cluster: CG33275-PA, isoform A; n=7; Diptera|Rep:
CG33275-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1876
Score = 131 bits (317), Expect = 6e-29
Identities = 94/295 (31%), Positives = 145/295 (49%), Gaps = 21/295 (7%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L GQ +V+FGN+ ++F FH FL +LER V F+E F+ LY+ Y
Sbjct: 1356 IPQPLRGQRNVIFGNIEKIFEFHNSHFLGELERYERNPLKVGAAFLEMESKFY-LYALYN 1414
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR---- 517
+N P+S+ L + F + Q++L KL LA+YLLKPVQR+ KY LLL+ L++
Sbjct: 1415 KNKPKSDTLLSEYGSS--FFKPKQMQLQDKLDLASYLLKPVQRMGKYALLLQQLVKACKG 1472
Query: 518 -----YSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLV 572
E + LQ+A + + L+ ND + ++ V++ +QG LL Q FLV
Sbjct: 1473 VEGAALQEIAADVEELQRAEEMVKFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFLV 1532
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSH-NKATYHFKHDLLMSQIGLTESV 631
+FL+E+ +LF K H N Y +K+ + S IGLT
Sbjct: 1533 ------WQGRGGKKTLRQVFLFEELVLFSKARRFPDHKNLDIYIYKNSIKTSDIGLTAHT 1586
Query: 632 KGDLRKFEVWRQGRCEVHT--ITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
KFE+W + R T + + ++K AW E I ++L Q K + R+ +
Sbjct: 1587 GDSATKFEIWFRKRKPDDTWMLQCMSEDIKNAWTEEISKLLWKQAKRNREVRLAE 1641
>UniRef50_A0NEN5 Cluster: ENSANGP00000031634; n=2; Culicidae|Rep:
ENSANGP00000031634 - Anopheles gambiae str. PEST
Length = 541
Score = 128 bits (310), Expect = 4e-28
Identities = 100/335 (29%), Positives = 169/335 (50%), Gaps = 28/335 (8%)
Query: 359 CLQAIYKDYDRRLEQWCDT----ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQAD-VL 413
C++ I + + L + T ++ S ++N GY EI P + L+P L G + ++
Sbjct: 209 CIEDILRKRNYALRELLTTEEAYVNDLSQIVN-GYIAEIRNPASTVLIPDDLKGGKERMV 267
Query: 414 FGNLHELFTFHQDVFLKDLERCI-SATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
FGN+ ++ +H+D FLK L++C+ + EL L +++ E +Y YCQN P SE +
Sbjct: 268 FGNIEAIYEWHRDHFLKALQKCLQNPYELGPL--IKRSERKLHMYVVYCQNKPVSEHI-- 323
Query: 473 TLVDTHL-FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT---TGL 528
V H+ + +L+L +KL L L+KPVQRI KY+LLLKD+L+++ +T GL
Sbjct: 324 --VQEHMSYFDELRLKLKYKLCLGDMLIKPVQRIMKYELLLKDILKHTLRAGLTEEVPGL 381
Query: 529 QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXX 588
++A+ M VV K ND M + ++ QG+LL+ G S N
Sbjct: 382 KEAMHIMQVVPKAANDMMDVGRLQKFEGKITTQGKLLLHGPLYCNSYN------SQKPKE 435
Query: 589 XHIFLYEKAMLFCK-PATKNSHNKATYHFKHDLLMSQIGLTE-SVKGDLRKFEVWR---Q 643
H+FL+E+ ++F + K Y +K + ++++ L + S + + +F + Q
Sbjct: 436 LHVFLFEQNIIFAEIVGKKTQFTSPNYIYKAHIQVNKMTLQDLSDQTNGNRFSLCSIDPQ 495
Query: 644 GRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELK 678
+ TAPT E+ W+ I +L Q LK
Sbjct: 496 RSSLSYICTAPTPELHSEWLNTIHEILKTQNDFLK 530
>UniRef50_UPI0000519A5C Cluster: PREDICTED: similar to CG33275-PC,
isoform C isoform 1; n=1; Apis mellifera|Rep: PREDICTED:
similar to CG33275-PC, isoform C isoform 1 - Apis
mellifera
Length = 1121
Score = 126 bits (304), Expect = 2e-27
Identities = 95/306 (31%), Positives = 149/306 (48%), Gaps = 36/306 (11%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L GQ +V+FGN+ +++ FH FL++LE+C + V CF+ + F+ LY+ Y
Sbjct: 649 IPQALRGQRNVIFGNVEKIYEFHGQHFLRELEQCEQSPMNVGQCFLRHEKKFY-LYALYN 707
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRY-SE 520
+N P S+ L T F Q QL LG K+ LA+YLLKPVQR+ KY LLL+ L++ ++
Sbjct: 708 KNKPNSDSLMAE-YGTAFFKQK-QLELGDKMDLASYLLKPVQRMGKYALLLQQLVKAGTD 765
Query: 521 CGSMTTG--------------------LQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ 560
+G L+ A + L+ ND + ++ V++ +
Sbjct: 766 LSEQMSGKDDKDEKDDGMKPIVEGEAELRAAEQMVRFQLRHGNDLLAMDSLRDCDVNVKE 825
Query: 561 QGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPAT-KNSHNKATYHFKHD 619
QG LL Q FLV +FL+E +LF K + N Y +KH
Sbjct: 826 QGRLLRQNEFLV-------WQGKGKKCLRQVFLFEDLILFSKARRFPDRKNLDIYIYKHS 878
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGR--CEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
+ + IGLT + KFE+W + R + +T+ + E+K+AW E + +L Q L
Sbjct: 879 IKTTDIGLTAVIADSPTKFEIWFRKRKPGDTYTLQCASEEIKKAWTEELSNLLWKQ--AL 936
Query: 678 KGERVR 683
+ VR
Sbjct: 937 RNREVR 942
>UniRef50_Q7Z2K2 Cluster: Transforming gene product TGAT; n=2;
Eutheria|Rep: Transforming gene product TGAT - Homo
sapiens (Human)
Length = 255
Score = 125 bits (301), Expect = 5e-27
Identities = 62/147 (42%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 84 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 142
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 143 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 200
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMH 547
S+ T+ L++A++ M +V + ND M+
Sbjct: 201 ASLDTSELERAVEVMCIVPRRCNDMMN 227
>UniRef50_UPI00015B606E Cluster: PREDICTED: similar to
ENSANGP00000031634; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000031634 - Nasonia
vitripennis
Length = 820
Score = 123 bits (296), Expect = 2e-26
Identities = 83/261 (31%), Positives = 130/261 (49%), Gaps = 13/261 (4%)
Query: 385 INSGYKEEIEKPENQHLLPPTLVGQAD-VLFGNLHELFTFHQDVFLKDLERCISATELVA 443
I GY + P LP L G D ++FGN+ ++ +H+D FLK LE C+ E +
Sbjct: 490 IVEGYMALMRDPNTDIPLPDDLKGGKDKMVFGNIEAMYEWHRDCFLKSLEHCLERPEELG 549
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F ++ E +Y YCQN P SE + +DT + + + +LGH+L L L+KPVQ
Sbjct: 550 PLF-KRYERKLHMYVVYCQNKPVSEYIVSEYIDT--YFEELRQKLGHRLQLCDLLIKPVQ 606
Query: 504 RITKYQLLLKDLLRYSE---CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ 560
RITKYQLLL++ LR ++ S GL A M V+ K ND M + G ++
Sbjct: 607 RITKYQLLLREALRLTQRTHRQSEIEGLTAAAHVMHVIPKAANDMMDVGRLQGFDGKITA 666
Query: 561 QGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSH-NKATYHFKHD 619
QG+LL+ G +V +FL+E+ ++F + K + Y +K
Sbjct: 667 QGKLLLHGPLMVAE----LSSLPSRGREWQVFLFEQNIIFSEAVGKKTQFTNPAYIYKAH 722
Query: 620 LLMSQIGLTESVKGDLRKFEV 640
+ ++++ L +S D KF +
Sbjct: 723 IQVNKMILEDS-PDDPEKFVI 742
>UniRef50_UPI0000D55959 Cluster: PREDICTED: similar to CG18214-PD,
isoform D; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG18214-PD, isoform D - Tribolium castaneum
Length = 1411
Score = 122 bits (293), Expect = 5e-26
Identities = 87/302 (28%), Positives = 148/302 (49%), Gaps = 14/302 (4%)
Query: 383 SLINSGYKEEIEKPENQHLLPPTLV-GQADVLFGNLHELFTFHQDVFLKDLERCI-SATE 440
SLI GY ++ PE + +P L G+ ++FGN+ ++ +H+D+FLK L++ I + TE
Sbjct: 440 SLIVDGYMATMKDPECEIPMPEDLRDGKDKMVFGNIEAIYDWHKDIFLKSLKKAIENPTE 499
Query: 441 LVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLK 500
L L + E +Y YC+N P SE + +++ + + +++LGHKL L L+K
Sbjct: 500 LAQL--FRRYERKLHMYVVYCKNKPVSEYIVSEYLES--YFEELRVKLGHKLQLCDLLIK 555
Query: 501 PVQRITKYQLLLKDLLRYSECGSMTT---GLQQALDCMLVVLKCVNDSMHQIAITGVPVD 557
PVQRI KYQL+LKD+L+Y+E +T L+ A M+ + K ND M + G
Sbjct: 556 PVQRIMKYQLMLKDILKYTERAGLTAEAEPLRTAYQIMVDLPKAANDMMDVGRLQGFDGK 615
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSH-NKATYHF 616
++ QG+LL+ G +FL+E++++ K + Y +
Sbjct: 616 ITAQGKLLLHGPLTCTD---VQGTVVGKNKDLQVFLFEQSIILSDVVGKKTQFTSPQYIY 672
Query: 617 KHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKE 676
K + ++++ L G + + + A T E++ W IK +L Q
Sbjct: 673 KTHIQVNKMNLHPEEDGFVLTSTDPHKPALAI-CCQAATQELQEQWFSTIKNILQTQRDF 731
Query: 677 LK 678
LK
Sbjct: 732 LK 733
>UniRef50_UPI0000F210AF Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1446
Score = 121 bits (291), Expect = 8e-26
Identities = 101/326 (30%), Positives = 165/326 (50%), Gaps = 44/326 (13%)
Query: 368 DRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVG--QADVLFGNLHELFTFHQ 425
DR +E+ +T + S ++ ++ NQ LL L+G + + LFGN+ +++ F+
Sbjct: 133 DRVVEEILETEKTYVQDLRSIVQDYLDCISNQSLL---LLGDEERNSLFGNIRDIYRFNS 189
Query: 426 DVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-----ERLRETLVDTHLF 480
++ L+DLE+C + +A CFV K E F +Y+ YC N PRS E +R +V F
Sbjct: 190 EL-LRDLEKCNANPVAIAKCFVAKSEDF-HIYTQYCTNYPRSVAVLTECMRNKMVAK--F 245
Query: 481 LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS-MTTGLQQALDCMLVVL 539
L+ Q L H LPL +YLLKPVQRI KY LLL ++ + E S M +Q+A+D M V
Sbjct: 246 LRERQESLKHSLPLGSYLLKPVQRILKYHLLLHEIATHLEKDSEMYDVIQEAIDTMQRVA 305
Query: 540 KCVND--SMHQIAITGVPV----------DLSQQGELLMQGSFLVVSENKXXXXXXXXXX 587
+ND H+ A+ + DL GEL+++G+F +
Sbjct: 306 WHINDMKRKHEHAVRLQEIQSLLTNWKGPDLIGYGELVLEGTFRIQRAKNERT------- 358
Query: 588 XXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCE 647
+FL++K +L K + TY +K +L + L E + + F V+ +
Sbjct: 359 ---LFLFDKLLLITK------KREETYSYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPK 409
Query: 648 V-HTITAPTVEVKRAWVERIKRVLLD 672
+ HT+ A + + K+ WV +KR++L+
Sbjct: 410 LQHTVQAKSQQDKKMWVLHLKRLILE 435
>UniRef50_UPI00015A58C2 Cluster: Pleckstrin homology
domain-containing family G member 1.; n=1; Danio
rerio|Rep: Pleckstrin homology domain-containing family
G member 1. - Danio rerio
Length = 1281
Score = 121 bits (291), Expect = 8e-26
Identities = 101/326 (30%), Positives = 165/326 (50%), Gaps = 44/326 (13%)
Query: 368 DRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVG--QADVLFGNLHELFTFHQ 425
DR +E+ +T + S ++ ++ NQ LL L+G + + LFGN+ +++ F+
Sbjct: 90 DRVVEEILETEKTYVQDLRSIVQDYLDCISNQSLL---LLGDEERNSLFGNIRDIYRFNS 146
Query: 426 DVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-----ERLRETLVDTHLF 480
++ L+DLE+C + +A CFV K E F +Y+ YC N PRS E +R +V F
Sbjct: 147 EL-LRDLEKCNANPVAIAKCFVAKSEDF-HIYTQYCTNYPRSVAVLTECMRNKMVAK--F 202
Query: 481 LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS-MTTGLQQALDCMLVVL 539
L+ Q L H LPL +YLLKPVQRI KY LLL ++ + E S M +Q+A+D M V
Sbjct: 203 LRERQESLKHSLPLGSYLLKPVQRILKYHLLLHEIATHLEKDSEMYDVIQEAIDTMQRVA 262
Query: 540 KCVND--SMHQIAITGVPV----------DLSQQGELLMQGSFLVVSENKXXXXXXXXXX 587
+ND H+ A+ + DL GEL+++G+F +
Sbjct: 263 WHINDMKRKHEHAVRLQEIQSLLTNWKGPDLIGYGELVLEGTFRIQRAKNERT------- 315
Query: 588 XXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCE 647
+FL++K +L K + TY +K +L + L E + + F V+ +
Sbjct: 316 ---LFLFDKLLLITK------KREETYSYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPK 366
Query: 648 V-HTITAPTVEVKRAWVERIKRVLLD 672
+ HT+ A + + K+ WV +KR++L+
Sbjct: 367 LQHTVQAKSQQDKKMWVLHLKRLILE 392
>UniRef50_Q4RTS6 Cluster: Chromosome 2 SCAF14997, whole genome
shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14997, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1334
Score = 120 bits (288), Expect = 2e-25
Identities = 96/343 (27%), Positives = 163/343 (47%), Gaps = 61/343 (17%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
++ G+ + IE+ +P + G+ ++FGN+H+++ +H++ F+ +LE+C+ E +
Sbjct: 224 IVVEGFMKRIEEKG----VPDDMKGKDKIVFGNIHQIYDWHREFFVGELEKCLDDHEHLP 279
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F+ K E +Y YCQN P+SE + + + + Q + +L ++ +L+KP+Q
Sbjct: 280 ELFI-KHERRLHMYVIYCQNKPKSEFI---VAEYDTYFDGIQQDIQSRLTISDFLIKPIQ 335
Query: 504 RITKYQLLLKDLLRY-SECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPV------ 556
RITKYQLLLKD L++ S+ G +++A+D M V K ND M+ + G V
Sbjct: 336 RITKYQLLLKDFLKFSSKAGMDCEQIEKAVDLMSQVPKLCNDMMNLGRLQGYEVCPLRLF 395
Query: 557 --------------------DLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEK 596
L+ QG+LL Q +F V ++ +FL+E+
Sbjct: 396 TAGSGGSFKPDRQSLLRLQGKLTSQGKLLQQETFFVTEQD---AGVLSRSKERRVFLFEQ 452
Query: 597 AMLFCKPATKNSHNKATYHFKHDL----------------------LMSQIGLTESVKGD 634
++F + K S Y FK + +S +GL ESV D
Sbjct: 453 IVIFSELLRKGSSTPG-YQFKKSIKVRPECSQEQLWVPAMLEPCPRQVSYLGLEESVDND 511
Query: 635 LRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
KF + +G E T+ A V++K+ WV I+ +L DQ K L
Sbjct: 512 PCKFVLSCRGSSERFTLQAANVDIKQVWVRHIQALLDDQSKFL 554
>UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF14723, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1484
Score = 119 bits (286), Expect = 3e-25
Identities = 99/323 (30%), Positives = 165/323 (51%), Gaps = 38/323 (11%)
Query: 368 DRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDV 427
DR +++ DT + S ++ +E NQ L + + + LFGN+ +++ F++D+
Sbjct: 110 DRVVQEILDTERTYVQDLRSIVEDYLENISNQSRLALSSEDK-EALFGNIQDIYHFNRDL 168
Query: 428 FLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-ERLRETLVDTHL--FLQAC 484
L +LE+C + +A CFV K E F +Y+ YC N PRS L E + + L F +
Sbjct: 169 -LHELEKCHADPVAIAECFVSKSEEF-HIYTQYCTNYPRSVAALTECMRNKALAKFFRER 226
Query: 485 QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVN 543
Q L H LPL +YLLKPVQRI KY LLL ++ + E + T +Q+A+D M V +N
Sbjct: 227 QESLRHSLPLGSYLLKPVQRILKYHLLLHEIANHMEKDTETYEVVQEAIDTMQRVAWHIN 286
Query: 544 D--SMHQIAITGVPV----------DLSQQGELLMQGSF-LVVSENKXXXXXXXXXXXXH 590
D H+ A+ + DL GEL+++G+F L ++N+
Sbjct: 287 DMKRKHEHAVRLQEIQSLLTNWKGPDLIGYGELVLEGTFRLQRAKNERT----------- 335
Query: 591 IFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV-H 649
+FL++K +L K + TY +K +L + L E + + F V+ ++ H
Sbjct: 336 LFLFDKLLLITK------KREETYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQH 389
Query: 650 TITAPTVEVKRAWVERIKRVLLD 672
T+ A + + KR W+ +KR++L+
Sbjct: 390 TVQAKSQQDKRMWILHLKRLILE 412
>UniRef50_UPI0000E80D31 Cluster: PREDICTED: hypothetical protein; n=2;
Gallus gallus|Rep: PREDICTED: hypothetical protein -
Gallus gallus
Length = 1260
Score = 116 bits (278), Expect = 3e-24
Identities = 101/329 (30%), Positives = 158/329 (48%), Gaps = 50/329 (15%)
Query: 396 PENQHL-LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRE--- 451
PE + L LP L G+ V+FGNL +L+ FH FL++LE C + V+ CF+ ++
Sbjct: 739 PEMERLDLPQDLRGKRSVIFGNLEKLYDFHSQYFLRELESCCNHPLRVSHCFLRHKDQFG 798
Query: 452 ---------------------TFFRLYSYYCQNIP-----RSERLRETLVDTHLFLQACQ 485
TFF+L + ++ L E L+ L Q Q
Sbjct: 799 MYALYSKNKPKSDSLLASHGNTFFKLRPWSAGDVSVPVQGPGAALAELLMSL-LCSQFKQ 857
Query: 486 LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG-LQQALDCMLVVLKCVN 543
++LG K+ LA+YLLKP+QR++KY LLLKDL++ SE G L+ A + + L+ N
Sbjct: 858 VQLGDKMDLASYLLKPIQRMSKYALLLKDLIKECSEAQEQELGYLRAAEEMVKFQLRHGN 917
Query: 544 DSMHQIAI---TGVP---VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKA 597
D + AI VP V+L +QG+L+ Q F + + H+FL+E
Sbjct: 918 DLLAMDAIRDCDAVPCGQVNLKEQGQLVRQDEFAIWLGRR--------KCQRHVFLFEDL 969
Query: 598 MLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPT 655
+LF KP + Y +K + IGLTE+ +FE+W R+ + + + A +
Sbjct: 970 ILFSKP-KRIEGGFDVYIYKRSFKTADIGLTENSGDSGLRFEIWFRRRKSSDTYILQASS 1028
Query: 656 VEVKRAWVERIKRVLLDQLKELKGERVRQ 684
E K+AW I ++L Q K R+++
Sbjct: 1029 AETKQAWTSDIAKILWQQAARNKEIRMQE 1057
>UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus
musculus (Mouse)
Length = 8891
Score = 114 bits (274), Expect = 9e-24
Identities = 78/280 (27%), Positives = 131/280 (46%), Gaps = 14/280 (5%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRL 456
E +P + Q V+F N+ ++ FH FLK+L+ C + VA+CF++ +E F +
Sbjct: 6664 ERSPRVPAAVASQKTVIFRNVQDISHFHSS-FLKELQGC-GTDDDVAMCFIKNQEAFEKY 6721
Query: 457 YSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHK-------LPLAAYLLKPVQRITKYQ 509
+ + + T V + + + L K PL YL +PV+R+ KYQ
Sbjct: 6722 LEFLVGRVQAESVVVSTPVQ-EFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQ 6780
Query: 510 LLLKDLLRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQG 568
LLK+L+R L +QA + + + + +H + P L GE + QG
Sbjct: 6781 ALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQG 6840
Query: 569 SFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLT 628
F +V E H+FL+ ++ CKP + + +Y F++ + +S I L
Sbjct: 6841 HF-IVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLN 6899
Query: 629 ESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
+ V+GD R FEVW R+ + + A TV +K +WV+ I
Sbjct: 6900 DQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEI 6939
>UniRef50_Q4RFA4 Cluster: Chromosome 8 SCAF15119, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15119, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1294
Score = 109 bits (263), Expect = 2e-22
Identities = 51/125 (40%), Positives = 82/125 (65%), Gaps = 3/125 (2%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ + +A F+ K+E +Y YC
Sbjct: 671 VPDDMRGKDKIVFGNIHQIYDWHKDFFLGELEKCLENPDRLAPLFI-KQERRLHMYIVYC 729
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT + + + RLGH+L + L+KPVQRI KYQLLLKDLL+ S+
Sbjct: 730 QNKPKSEHIVSEYIDT--YFEDLKQRLGHRLQITDLLIKPVQRIMKYQLLLKDLLKMSKK 787
Query: 522 GSMTT 526
+ T
Sbjct: 788 AGLET 792
Score = 58.0 bits (134), Expect = 9e-07
Identities = 26/69 (37%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +V + ++FGN+ +L+ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 33 IPAGIVNKEHIIFGNMQDLYEFHHNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVSYC 91
Query: 462 QNIPRSERL 470
+N P S +L
Sbjct: 92 KNKPDSTQL 100
Score = 51.2 bits (117), Expect = 1e-04
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 528 LQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXX 587
++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 123 IKDGLEVMLSVPKKANDAMHLSMLEGFDGNIDSQGELILQESFQVWDPK----TLIRKGR 178
Query: 588 XXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
H+FL+E +++F K K+S+ ++ Y +K L S I
Sbjct: 179 DRHLFLFEMSLVFSK-EVKDSNGRSKYLYKSKLFASSI 215
>UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo
sapiens (Human)
Length = 7968
Score = 109 bits (262), Expect = 3e-22
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 5786
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 5905
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 5906 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 5965
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 5966 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 5999
>UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep:
LOC572412 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1095
Score = 108 bits (260), Expect = 5e-22
Identities = 74/274 (27%), Positives = 128/274 (46%), Gaps = 12/274 (4%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQ 462
PP + Q + +F N+++L FH + L DL C + + +A+ F++ E F + Y
Sbjct: 246 PPEITMQKETIFRNINDLKAFHSSL-LPDLRDCDTDDD-IAMHFLKNSEGFEKYLQYLIG 303
Query: 463 NIPRSERLRETLVDTHLF------LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ + E V + L G L + AYL +P +RI KY+ LLK+L+
Sbjct: 304 QLQAESIISEKQVHQYFKDYSVSELANVDPSEGPVLSINAYLQRPPERIQKYRALLKELI 363
Query: 517 RYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-ITGVPVDLSQQGELLMQGSFLVVSE 575
R L + M+ L +++ H ++ I P +L GE + QG F V E
Sbjct: 364 RNKARNGQNCCLLEQAYAMVSSLSQRSENTHHVSLIENYPANLEALGEPIRQGPF-TVWE 422
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDL 635
H+FL++ ++ CK + + TY FK+ + ++ I + E+V+GD
Sbjct: 423 GAPGVRTSSRGHHRHVFLFKNHVVICKQKRDTNTDTQTYVFKNMMKLTNIDVNETVEGDE 482
Query: 636 RKFEVW--RQGRCEVHTITAPTVEVKRAWVERIK 667
R FE+W R+ +T+ A TV +K W+ ++
Sbjct: 483 RAFEIWHEREDSVRKYTLQARTVIIKNPWLRDLR 516
>UniRef50_A1L390 Cluster: Pleckstrin homology domain-containing
family G member 3; n=4; Homo/Pan/Gorilla group|Rep:
Pleckstrin homology domain-containing family G member 3
- Homo sapiens (Human)
Length = 1219
Score = 108 bits (259), Expect = 6e-22
Identities = 87/280 (31%), Positives = 134/280 (47%), Gaps = 34/280 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
Q LFGN+ ++ + + L+DL+ C S VA CFVE+ + F +Y+ YC N P S
Sbjct: 134 QVSALFGNIENIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEF-DIYTQYCNNYPNSV 191
Query: 468 ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSM 524
L E + D F + Q L H LPL +YLLKPVQRI KY LLL+++ + + E
Sbjct: 192 AALTECMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAKHFDEEEDG 251
Query: 525 TTGLQQALDCMLVVLKCVND------------SMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ A+D M V +ND + + I DL+ GEL+++G+F V
Sbjct: 252 FEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEGTFRV 311
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVK 632
FL++K +L K + H + +K ++ S + L ES +
Sbjct: 312 HRVRNERT----------FFLFDKTLLITK--KRGDH----FVYKGNIPCSSLMLIESTR 355
Query: 633 GDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
L + + ++I A TVE KR W IKR++L+
Sbjct: 356 DSLCFTVTHYKHSKQQYSIQAKTVEEKRNWTHHIKRLILE 395
>UniRef50_UPI0000EB3077 Cluster: pleckstrin homology domain
containing, family G, member 3; n=3; Canis lupus
familiaris|Rep: pleckstrin homology domain containing,
family G, member 3 - Canis familiaris
Length = 1224
Score = 107 bits (257), Expect = 1e-21
Identities = 87/280 (31%), Positives = 133/280 (47%), Gaps = 34/280 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
Q LFGN+ ++ + + L+DL+ C S VA CFVE+ + F +Y+ YC N P S
Sbjct: 133 QVSALFGNIENIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEF-DIYTQYCNNYPNSV 190
Query: 468 ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSM 524
L E + D F + Q L H LPL +YLLKPVQRI KY LLL+++ + + E
Sbjct: 191 AALTECMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAKHFDEEEDG 250
Query: 525 TTGLQQALDCMLVVLKCVND------------SMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ A+D M V +ND + + I DL+ GEL+++G+F V
Sbjct: 251 FEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTIYGELVLEGTFRV 310
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVK 632
FL++KA+L K + H + +K + S + L ES +
Sbjct: 311 HRVRNERT----------FFLFDKALLITK--KRGDH----FVYKGHIPCSSLMLIESTR 354
Query: 633 GDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
L + + + I A T E KR+W IKR++L+
Sbjct: 355 DSLCFTVTHYKHSKQQYNIQAKTAEEKRSWTHHIKRLILE 394
>UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep:
Obscurin-MLCK - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 2009
Score = 107 bits (257), Expect = 1e-21
Identities = 71/290 (24%), Positives = 134/290 (46%), Gaps = 10/290 (3%)
Query: 385 INSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVAL 444
+N + ++ E +P T++ Q + +F N+ ++ +FH+ L LE C S + VA
Sbjct: 17 MNFFVEHHLQYLETSCKVPLTILSQKEYIFRNIRDIASFHECCILPKLEMCFSDDD-VAQ 75
Query: 445 CFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLG----HKLPLAAYLLK 500
CFV F +Y + +P++E H F Q + L + YL +
Sbjct: 76 CFVGYAADF-EMYLQFITGLPQAEACISDKNTQHFFKQYANIELADLDTQVFSVGTYLQR 134
Query: 501 PVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-ITGVPVDLS 559
P++RI Y+ +LK+++R L + M+ L +++H ++ I P L
Sbjct: 135 PMERIETYKTVLKEMIRNKAKSGQNCCLLEDAFAMVSSLPWRAENLHHLSMIENYPAPLK 194
Query: 560 QQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHD 619
GE + QG F E H+FL++ ++FCKP + + Y FK+
Sbjct: 195 GLGEPIRQGHFTAWEEIPEVKSSQRGHHR-HVFLFKDCIVFCKPKREVGTHTEAYIFKNK 253
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTI--TAPTVEVKRAWVERIK 667
+ +S I + ++ +GD R F +W + R V I A ++ ++ +W++ ++
Sbjct: 254 MKLSDIDVKDTAEGDDRSFGLWHEHRGMVRKIILQARSILLRLSWLKDLR 303
>UniRef50_Q4S810 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF14710, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 442
Score = 107 bits (257), Expect = 1e-21
Identities = 82/266 (30%), Positives = 124/266 (46%), Gaps = 38/266 (14%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P L G+ V+FGNL +L FH FL +LE C +VA CF+ E+ F LY+ Y
Sbjct: 39 VPQDLRGKRGVIFGNLEKLHDFHSHYFLPELEACEREAAMVARCFLRHSES-FGLYALYS 97
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDL------ 515
+N P+S+ L L H + Q LG + L++YLL+P+QRI+KY LLL+D+
Sbjct: 98 KNKPQSDAL--ILHRPHDIFKRKQQELGDLMDLSSYLLRPIQRISKYSLLLQDVLTLAGS 155
Query: 516 --------------------LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVP 555
LR S+ +Q A D + ++ ND + A+
Sbjct: 156 HRPKGPTQEPPLSPDVYVPDLRSSDWERERAEIQAAADLVQFQMRHGNDLLTMDAVRECD 215
Query: 556 VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYH 615
V+L +QG+L+ Q F V K +FL+E +LF K ++ N+ Y
Sbjct: 216 VNLKEQGQLVRQDEFTVSFRKK--------KCVRRVFLFEDLILFSKTKKTDTGNE-VYV 266
Query: 616 FKHDLLMSQIGLTESVKGDLRKFEVW 641
+KH S +G+T FE+W
Sbjct: 267 YKHSFKTSDVGMTHHSSMGSLCFEIW 292
>UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing
family G member 1; n=29; Eumetazoa|Rep: Pleckstrin
homology domain-containing family G member 1 - Homo
sapiens (Human)
Length = 1385
Score = 106 bits (255), Expect = 2e-21
Identities = 87/283 (30%), Positives = 140/283 (49%), Gaps = 39/283 (13%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
+ LFGN+ +++ F+ ++ L+DLE C + +A CFV K E F +Y+ YC N PRS
Sbjct: 155 ERSALFGNIQDIYHFNSEL-LQDLENCENDPVAIAECFVSKSEEF-HIYTQYCTNYPRSV 212
Query: 469 R-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
L E + + L F + Q L H LPL +YLLKPVQRI KY LLL ++ + + T
Sbjct: 213 AVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLD--KDT 270
Query: 526 TG---LQQALDCMLVVLKCVND--SMHQIAITGVPV----------DLSQQGELLMQGSF 570
G + A+D M V +ND H+ A+ + DL+ GEL+++G+F
Sbjct: 271 EGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTF 330
Query: 571 LVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTES 630
+ +FL++K +L K T+ +K +L + L E
Sbjct: 331 RIQRAKNERT----------LFLFDKLLLITK------KRDDTFTYKAHILCGNLMLVEV 374
Query: 631 VKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRVLLD 672
+ + F V+ ++ HT+ A + + KR WV +KR++L+
Sbjct: 375 IPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILE 417
>UniRef50_Q4VAC9 Cluster: Pleckstrin homology domain-containing
family G member 3; n=21; Tetrapoda|Rep: Pleckstrin
homology domain-containing family G member 3 - Mus
musculus (Mouse)
Length = 1341
Score = 105 bits (253), Expect = 3e-21
Identities = 85/280 (30%), Positives = 133/280 (47%), Gaps = 34/280 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
Q LFGN+ ++ + + L+DL+ C S VA CFVE+ + F +Y+ YC N P S
Sbjct: 134 QVSALFGNIESIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEF-DIYTQYCNNYPNSV 191
Query: 468 ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSM 524
L E + D F + Q L H LPL +YLLKPVQR+ KY LLL+++ + + E
Sbjct: 192 AALTECMQDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEIAKHFDEEEDG 251
Query: 525 TTGLQQALDCMLVVLKCVND------------SMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ A+D M V +ND + + I DL+ GEL+++ +F V
Sbjct: 252 FEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRV 311
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVK 632
FL++K +L K + H + +K + S + L ES +
Sbjct: 312 HRVRNDRT----------FFLFDKILLITK--KRGDH----FVYKGHIPCSSLMLIESTR 355
Query: 633 GDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
L + + ++I A TVE KR+W IKR++L+
Sbjct: 356 DSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRLILE 395
>UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pleckstrin homology
domain-containing family G member 1 - Apis mellifera
Length = 1354
Score = 99 bits (238), Expect = 2e-19
Identities = 93/309 (30%), Positives = 149/309 (48%), Gaps = 43/309 (13%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
Q LF N+ ++F F+++ FLK++E C VA F+ K ++ F++Y+ YC N P +
Sbjct: 299 QLSNLFSNIEDIFEFNRE-FLKEIEECGLDPVSVANTFI-KHKSGFKVYTEYCTNYPSTV 356
Query: 469 RLRETLVD---THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR--YSEC-- 521
+ L+ T Q Q L H LPL ++LL PVQRI KY LLL++L + ++C
Sbjct: 357 SVLTDLMSQEKTACAFQERQAALKHALPLGSFLLTPVQRILKYHLLLENLSKEYAADCEV 416
Query: 522 -GSMTTG---LQQALDCMLVVLKCVN--DSMHQIAIT---------GVP-VDLSQQGELL 565
+ T G ++ AL M + K +N H+ A+ G P DL+ GEL+
Sbjct: 417 RENKTEGSKAIEAALAAMTDIAKHINAMKRRHEHAVRVQEIQSLLYGWPGPDLTTSGELV 476
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
+G F + H+FL+++ +L K K Y K ++ S +
Sbjct: 477 AEGRFRM----------RGAKAPRHVFLFDRMLLLTK---KKEDGLLVY--KAHIMCSNL 521
Query: 626 GLTESVKGDLRKFEV--WRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
L ES+ G+ F V + R + +T+ A +E K+ W +IKRV+L+ + R
Sbjct: 522 MLIESIPGESLSFHVIPFNNPRLQ-YTLQARNLEQKKEWTFQIKRVILENYNAVIPSHAR 580
Query: 684 QYGLQHHRT 692
Q LQ +T
Sbjct: 581 QLVLQLGQT 589
>UniRef50_UPI0000D55943 Cluster: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Pleckstrin homology domain-containing family G member 1
- Tribolium castaneum
Length = 1421
Score = 97.1 bits (231), Expect = 2e-18
Identities = 87/292 (29%), Positives = 135/292 (46%), Gaps = 34/292 (11%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-ERLR 471
LF NL E++ F++ FL L +A F++ ++ F +Y+ YC N PR+ E L
Sbjct: 633 LFSNLEEIYRFNRS-FLDQLRAADFNPTKIANVFIQN-DSGFAVYNEYCTNYPRTMEVLS 690
Query: 472 ETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQ 529
E D + + Q+ L H LPL +YLLKPVQRI KY LLL+ L + + +
Sbjct: 691 ELTRDEKMASLFREKQMALSHALPLGSYLLKPVQRILKYHLLLQRLSKQCDTDHKPA-VD 749
Query: 530 QALDCMLVVLKCVNDSM--HQIAITGVPV----------DLSQQGELLMQGSFLVVSENK 577
AL M V +N H+ A+ + DL+ GEL+ +G+F V
Sbjct: 750 LALATMTAVASSINSMKRKHEHAVRVHEIQSQLYGWTGPDLTTLGELIAEGTFRV----- 804
Query: 578 XXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRK 637
H+FL++K +L K N + A + H + S + L E V+G+
Sbjct: 805 -----NGARGRRHVFLFDKVLLMAK----NKQDGALAYKSH-IECSNLMLVEQVRGEPLS 854
Query: 638 FEVWRQGRCEVH-TITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQ 688
F+V + T+ A + + KR W +IKRV+L+ + RQ +Q
Sbjct: 855 FQVLPFDNPRLQCTLRARSPQNKREWTLQIKRVILENYSAVIPNHARQLVMQ 906
>UniRef50_Q3B839 Cluster: BRSK2 protein; n=5; Catarrhini|Rep: BRSK2
protein - Homo sapiens (Human)
Length = 296
Score = 93.1 bits (221), Expect = 2e-17
Identities = 46/106 (43%), Positives = 70/106 (66%), Gaps = 4/106 (3%)
Query: 591 IFLYEKAMLFCKPATKNS--HNKA-TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCE 647
+FL+EKA+LFCK +N + KA +Y +K L M+ +G+TE+VKGD +KFE+W R E
Sbjct: 3 LFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREE 62
Query: 648 VHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTL 693
V+ + APT E+K AWV I++VL QL+ + E + L+ ++L
Sbjct: 63 VYIVQAPTPEIKAAWVNEIRKVLTSQLQACR-EASQHRALEQSQSL 107
>UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family G (with RhoGef
domain) member 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to pleckstrin homology domain
containing, family G (with RhoGef domain) member 1 -
Nasonia vitripennis
Length = 1440
Score = 91.5 bits (217), Expect = 8e-17
Identities = 93/319 (29%), Positives = 147/319 (46%), Gaps = 50/319 (15%)
Query: 403 PPTLVGQADV--LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYY 460
P +L+ ++ LF N+ ++F F+++ FL L+ VA F+E + F++Y+ Y
Sbjct: 267 PASLIRDLELNGLFSNIEDIFEFNRN-FLSALDSSGLDPIAVANTFIE-HNSGFKVYTEY 324
Query: 461 CQNIPRSERLRETLVDTHLFLQACQLR---LGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
C N P + + L+ + +A + R LGH LPL ++LLKPVQRI KY LLL++L +
Sbjct: 325 CTNYPTTVSILTELMSQEVIARAFRERQAALGHLLPLGSFLLKPVQRILKYHLLLENLSK 384
Query: 518 YSEC------------GSMTTG---LQQALDCMLVVLKCVN--DSMHQIAIT-------- 552
E S G L+ AL M + + +N H+ A+
Sbjct: 385 EFEAKLELEGSDEADNSSAAEGRAALEGALQAMTGIARHINAMKRKHEHAVRVQEIQSLL 444
Query: 553 -GVP-VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHN 610
G P DL+ GEL+ +GSF + H FL+++ +L K K
Sbjct: 445 YGWPGPDLTTSGELIAEGSFRM----------RGAKAPRHAFLFDRMLLLTK---KREDG 491
Query: 611 KATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRV 669
Y K +L S + L ES+ G+ F V ++ + + A +E KR W +IKRV
Sbjct: 492 LLVY--KAHILCSNLTLMESIPGEPLSFHVIPFDNSQLQYKLQARNLEQKREWTLQIKRV 549
Query: 670 LLDQLKELKGERVRQYGLQ 688
+L+ + RQ LQ
Sbjct: 550 ILENYNAVIPSHARQLVLQ 568
>UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 729
Score = 90.6 bits (215), Expect = 1e-16
Identities = 87/311 (27%), Positives = 152/311 (48%), Gaps = 43/311 (13%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-ERLR 471
LFGN+ +++ F+ ++ L+ L+ C S +A CFV+K E +F++Y+ YC N P S L
Sbjct: 167 LFGNIEDIYEFNSEL-LQSLDMCDSDPVAIAQCFVDKSE-YFQIYTQYCTNYPNSVAALT 224
Query: 472 ETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGL 528
+ + + L F + Q L LPL +YLLKPVQRI KY LLL+++ ++ + +
Sbjct: 225 DCMRNKTLAKFFRDRQASLKCSLPLGSYLLKPVQRILKYHLLLQEIAKHLDLHEEGYEVV 284
Query: 529 QQALDCMLVVLKCVND--SMHQIAITGVPV----------DLSQQGELLMQGSFLVVSEN 576
Q+A+D M V +ND H+ A+ + DL+ GEL+++G+F V+
Sbjct: 285 QEAIDTMTGVAWYINDMKRKHEHAVRVQEIQSLLINWKGPDLTTYGELVLEGTFHVLRAK 344
Query: 577 KXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+FL+++ +L K + H Y +K + S + L ++ K L
Sbjct: 345 NTRT----------LFLFDRMLLITK--KRGEH----YVYKTHISCSTLMLLDTAKDPLL 388
Query: 637 KFEVWRQGRCEVHTITA--PTVEVKRA------WVERIKRVLLDQLKELK-GERVRQYGL 687
+ + + HT+ A T+++ + ER+KR L Q +E G R +
Sbjct: 389 FSVLHFKHPKQPHTVQAREATLDIPNSPGKYHYSPERLKRTELCQKEEFHLGRRNGRRSS 448
Query: 688 QHHRTLIQTSS 698
H +++ S+
Sbjct: 449 VFHAAVLKVSA 459
>UniRef50_Q4SB72 Cluster: Chromosome undetermined SCAF14677, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14677,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 856
Score = 89.0 bits (211), Expect = 4e-16
Identities = 66/180 (36%), Positives = 95/180 (52%), Gaps = 19/180 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
Q LF N+ +++ F+ D+ L+DLER A +A CFVE+ E F +Y+ YC N P S
Sbjct: 74 QVSTLFCNIEDIYEFNSDL-LEDLERSQHAAA-IAECFVERSEAF-DIYTLYCMNYPSSV 130
Query: 469 R-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSM 524
LRE + L F Q + L H LPL YLLKPVQRI KY LLL++L + + +
Sbjct: 131 AVLRECMNTRSLAQFFQERRTTLNHSLPLETYLLKPVQRILKYHLLLQELSKHFDKSDPG 190
Query: 525 TTGLQQALDCMLVVLKCVND----SMHQIAITGVP--------VDLSQQGELLMQGSFLV 572
++ A+ M V +ND H + + + +LS GEL+++GSF V
Sbjct: 191 YEVVEDAIVTMTAVAWYINDMKRKQEHAVRLQEIESQLVNWTGPELSGFGELVLEGSFKV 250
>UniRef50_UPI0000DA3D65 Cluster: PREDICTED: similar to mcf.2
transforming; n=1; Rattus norvegicus|Rep: PREDICTED:
similar to mcf.2 transforming - Rattus norvegicus
Length = 600
Score = 88.6 bits (210), Expect = 5e-16
Identities = 38/81 (46%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ P+ L+PP L + DVLFGN+ E++ FH ++F+ LE C A E V CF+
Sbjct: 358 GYRSEMDNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFL 417
Query: 448 EKRETFFRLYSYYCQNIPRSE 468
E++E F++Y+ YCQN PRSE
Sbjct: 418 ERKED-FQMYAKYCQNKPRSE 437
>UniRef50_Q9H7P9 Cluster: Pleckstrin homology domain-containing
family G member 2; n=24; Euteleostomi|Rep: Pleckstrin
homology domain-containing family G member 2 - Homo
sapiens (Human)
Length = 1386
Score = 88.6 bits (210), Expect = 5e-16
Identities = 85/285 (29%), Positives = 134/285 (47%), Gaps = 33/285 (11%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
V Q LF N+ +++ F ++ L+DLE SA +A CFV++ E F +Y+ YC N P
Sbjct: 142 VEQVGTLFANIEDIYEFSSEL-LEDLENSSSAGG-IAECFVQRSEDF-DIYTLYCMNYPS 198
Query: 467 S-ERLRETLVD--THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
S LRE + L+LQ Q +L H LPL ++LLKPVQRI KY LLL++L ++ G
Sbjct: 199 SLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGP 258
Query: 524 MTTG---LQQALDCMLVVLKCVND----SMHQIAITGVP--------VDLSQQGELLMQG 568
T G +++A+ M V +ND H + V +LS GEL+++G
Sbjct: 259 GTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEG 318
Query: 569 SFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLT 628
+F +FL+ + +L K Y +K + + ++
Sbjct: 319 AF----RGGGGGGPRLRGGERLLFLFSRMLLVAK------RRGLEYTYKGHIFCCNLSVS 368
Query: 629 ESVKGDLRKFEVWRQG-RCEVHTITAPTVEVKRAWVERIKRVLLD 672
ES + L F+V H + A E KR W+ ++R+ +
Sbjct: 369 ESPRDPL-GFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFE 412
>UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep:
MGC166429 protein - Bos taurus (Bovine)
Length = 813
Score = 88.2 bits (209), Expect = 7e-16
Identities = 53/177 (29%), Positives = 89/177 (50%), Gaps = 4/177 (2%)
Query: 493 PLAAYLLKPVQRITKYQLLLKDLLRY-SECGSMTTGLQQALDCMLVVLKCVNDSMHQIAI 551
PL +L +PV+R+ +YQ LLK+L+R + G L+QA + + + + +H +
Sbjct: 30 PLQHFLEQPVERVQQYQALLKELIRNKARNGQNCALLEQAYAVVSALPQRAENQLHVSLM 89
Query: 552 TGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNK 611
P L GE + QG F +V E H+FL+ ++ CKP + +
Sbjct: 90 ENYPGTLEALGEPIRQGHF-IVWEGAPGARMPWKGHHRHVFLFRNHLVVCKPRRDSRTDT 148
Query: 612 ATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
+Y F++ + +S I L + V+GD R FE+W R+ + + A TV K +WV+ I
Sbjct: 149 FSYVFRNMMKLSSIDLNDQVEGDDRAFEIWHEREDSVRKYLLQARTVITKNSWVKEI 205
>UniRef50_Q8TER5 Cluster: FLJ00128 protein; n=30; Tetrapoda|Rep:
FLJ00128 protein - Homo sapiens (Human)
Length = 1546
Score = 88.2 bits (209), Expect = 7e-16
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
L P L G L +FH+ FL++L+ C + + CF+ + F S Y
Sbjct: 1142 LTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQF----SLYA 1197
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-- 519
Q + +L L + + G LP A L +P++++T+Y LL++LLR +
Sbjct: 1198 QYVKHRHKLENGLAALSPSSKG-SMEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGP 1254
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
E S L A+ + D + A+ G +DL +QG+LL + F V+ K
Sbjct: 1255 ELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK-- 1312
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+E +LF K ++ + +K + +GLTE++ FE
Sbjct: 1313 ------KCLRHVFLFEHLLLFSKLKGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFE 1365
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ E +T+ A + E+K W I ++L Q K RV+Q
Sbjct: 1366 LWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQ 1412
>UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2646
Score = 87.4 bits (207), Expect = 1e-15
Identities = 68/274 (24%), Positives = 123/274 (44%), Gaps = 14/274 (5%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQ 462
P + Q + +F N+ ++ +FH VF L C + + VA+CF++ +E F + Y
Sbjct: 1924 PSEVSSQKEAIFRNIEDIKSFHNRVFFSKLNECETDDD-VAMCFLKNKEGFEKYMQYLVG 1982
Query: 463 NIPRSERLRETLVDTHLFLQACQLRLGHKLP-------LAAYLLKPVQRITKYQLLLKDL 515
P + + V +++ G K P ++AYL +P++RI KY+++LK+L
Sbjct: 1983 QSPAESAVGDRTVHRFFKEYTDKIQAG-KAPEDPAVHSVSAYLQQPLERIQKYKVVLKEL 2041
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-ITGVPVDLSQQGELLMQGSFLVVS 574
+R L + M+ L +++ H ++ I P L GE + QG F V
Sbjct: 2042 IRNKARNGQNCCLLEEAYAMVSALPQRSENSHHVSMIENYPATLEVLGEPIRQGPF-QVW 2100
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL++ + CKP ++ +Y FK +++ + S
Sbjct: 2101 EGAPGIRTSSRGHHRHVFLFKNYCIICKPKRDSNTETQSYVFK-NMMKVNVPHVPSPLIF 2159
Query: 635 LRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKR 668
F + C T+ A T VK +W++R++R
Sbjct: 2160 SALFFFFFLLTCA--TLQARTGIVKNSWLDRLQR 2191
>UniRef50_UPI0001555B97 Cluster: PREDICTED: similar to FLJ00056
protein, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to FLJ00056 protein, partial -
Ornithorhynchus anatinus
Length = 558
Score = 87.0 bits (206), Expect = 2e-15
Identities = 81/282 (28%), Positives = 129/282 (45%), Gaps = 24/282 (8%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE-R 469
+ L G L FH+ FL +L+ C + V CF+ + F LY+ Y ++ E R
Sbjct: 157 NALLGARERLHRFHRLHFLPELQGCAARPLRVGACFLRYGDQF-SLYTQYMKHRHELETR 215
Query: 470 LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQ 529
L T + P L +P++++ Y LL++LL+ E GS +
Sbjct: 216 LAALSTPTK---GSGPSGTSEGCPSPWPLQRPLEQLGHYGRLLRELLQ--EAGSERGPER 270
Query: 530 QALDCMLVVLKCVNDSMHQI----AITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXX 585
QAL L +L+ + H + A+ G VDL +QG LL++ +F V+ +
Sbjct: 271 QALAAALQLLQDQEEEGHNLLAVEAVRGCEVDLKEQGPLLLRDTFTVLCGRR-------- 322
Query: 586 XXXXHIFLYEKAMLFCKPATKNSHNKA-TYHFKHDLLMSQIGLTESVKGDLRKFEVW--R 642
H+FL+E +LF KP K + A + FK + +G+TE++ FE+W R
Sbjct: 323 KSLRHVFLFEHLLLFSKP--KGAEGSAGPFVFKQAFQTADMGMTENIGDTGLCFELWFRR 380
Query: 643 QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+ E +T+ A T E K W I ++L Q K RV+Q
Sbjct: 381 RRSREAYTLQAATPERKHKWTCAIAQLLWRQAAHSKDIRVQQ 422
>UniRef50_A7SFH2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1005
Score = 86.2 bits (204), Expect = 3e-15
Identities = 44/111 (39%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQ 462
P L G +F N+ ++ +H + F L+ C + F LY+ YC+
Sbjct: 357 PSELKGNQKFIFSNIQDIHDWHANKFYTFLKDCEDMPSQLGDVFTYAESKLEELYTVYCR 416
Query: 463 NIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLK 513
N P+S+ L T DT F Q C+ RLGH+L + YL+KPVQRITKYQLLL+
Sbjct: 417 NKPKSDSLVMTYKDT--FFQECRHRLGHRLQITDYLIKPVQRITKYQLLLR 465
Score = 53.6 bits (123), Expect = 2e-05
Identities = 34/122 (27%), Positives = 67/122 (54%), Gaps = 12/122 (9%)
Query: 547 HQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATK 606
+Q+ + P D G+L+++ + LVV++ K ++FL+EK +L +P+ +
Sbjct: 460 YQLLLRAKPDDT---GDLILRET-LVVADGKAKQKSREC----NVFLFEKVILLTEPSEE 511
Query: 607 NSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRC--EVHTITAPTVEVKRAWVE 664
+ T F + + + +G TESV D K+ VW + R E++ + AP++E+K+ W++
Sbjct: 512 GG--RPTLRFLNSIKVRGLGQTESVDSDPCKWAVWLRKRSGSEIYVLKAPSIEIKQIWMK 569
Query: 665 RI 666
I
Sbjct: 570 AI 571
>UniRef50_UPI0000F3273F Cluster: pleckstrin homology domain
containing, family G (with RhoGef domain) member 3; n=2;
Tetrapoda|Rep: pleckstrin homology domain containing,
family G (with RhoGef domain) member 3 - Bos Taurus
Length = 892
Score = 85.0 bits (201), Expect = 7e-15
Identities = 78/244 (31%), Positives = 117/244 (47%), Gaps = 38/244 (15%)
Query: 447 VEKRETFFRLYSYYCQNIPRS-ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQ 503
VE +E F +Y+ YC N P S L E + D F + Q L H LPL +YLLKPVQ
Sbjct: 116 VESQE--FDIYTQYCNNYPNSVAALTECMQDKQQAKFFRDQQDLLQHSLPLGSYLLKPVQ 173
Query: 504 RITKYQLLLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVND------------SMHQIA 550
RI KY LLL+++ + + E ++ A+D M V +ND + +
Sbjct: 174 RILKYHLLLQEIAKHFDEEEDGFEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLL 233
Query: 551 ITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHN 610
+ DL+ GEL+++G+F V FL++KA+L K + H
Sbjct: 234 LNWTGPDLTTYGELVLEGTFRV----------HRVRSEKTFFLFDKALLVTK--KRGGH- 280
Query: 611 KATYHFKHDLLMSQIGLTESVKGDLRKFEV--WRQGRCEVHTITAPTVEVKRAWVERIKR 668
+ +K + S + L ES + L F V ++ G+ + + I A TVE KR W IKR
Sbjct: 281 ---FVYKSHIPCSSLMLIESTRESL-CFTVTHYKHGK-QQYNIQAKTVEEKRRWTHHIKR 335
Query: 669 VLLD 672
++LD
Sbjct: 336 LILD 339
>UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome shotgun
sequence; n=4; Tetraodontidae|Rep: Chromosome 1
SCAF14995, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 5505
Score = 85.0 bits (201), Expect = 7e-15
Identities = 70/289 (24%), Positives = 137/289 (47%), Gaps = 17/289 (5%)
Query: 393 IEKPENQHLLPPTLVGQADVL--FGNLHELFTFHQDVFLKDLERCISATELVALCFVEKR 450
+EK + L P L QA+ L G+ E + + L C + + VA+ F+
Sbjct: 4064 LEKKRKETL--PQLRTQAEDLDGIGSTGEEYRRSLRSIIPGLRECATDDD-VAMLFITHT 4120
Query: 451 ETFFRLYSYYCQNIPRSER------LRETLVDTHLFLQACQLRL-GHKLPLAAYLLKPVQ 503
++F + Y +Y + ++E +++ T+L + L + + ++ +PV+
Sbjct: 4121 DSFEK-YLHYMEGQAQAEACITDKAIQQFFKVTNLTTRESAASLEAAAMDVLTFIQQPVE 4179
Query: 504 RITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-ITGVPVDLSQQG 562
RI YQ LLK+L++ + L + ++ L +D++HQ++ I P L+ G
Sbjct: 4180 RIQTYQALLKELIKNKAKSGQSCCLLENSFSLVSSLPWRSDNLHQVSLIENYPAPLTALG 4239
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
E + QG F V EN +FL+++ ++ CK +S N TY FK+ + +
Sbjct: 4240 EPVRQGIFTVWEENPEVKTTSRGHQR-QVFLFKECVVLCKLKRDSSINSDTYVFKNKMKL 4298
Query: 623 SQIGLTESVKGDLRKFEVWRQ--GRCEVHTITAPTVEVKRAWVERIKRV 669
+ + + ESV GD + + +W + G +T+ + VK +W++ +K +
Sbjct: 4299 NDVEIKESVDGDEKSWGLWHEHRGSLRRYTLQGRSSVVKTSWLKDLKEL 4347
>UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to
ENSANGP00000021721; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021721 - Nasonia
vitripennis
Length = 1247
Score = 84.6 bits (200), Expect = 9e-15
Identities = 66/287 (22%), Positives = 133/287 (46%), Gaps = 15/287 (5%)
Query: 391 EEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKR 450
E KP + +P + +++F NL ++ FH V ++ ++ ++ F+ +
Sbjct: 50 ERYLKPLDNPAVPRAVRDNKEIIFTNLKQIAEFHNTVLIEGVKYYADQPRMLGKTFL-RL 108
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
E F + YC++ P ++ ++ + + + +LG ++ +L P+QRI YQL
Sbjct: 109 ERDFDKHVAYCRDEPVAQDFLQSNNEVREYFEELSHKLGDDKSVSEHLKLPIQRINDYQL 168
Query: 511 LLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGS 569
LLK+L++YS G LQ+AL+ ML + D+ I G ++ + G LL
Sbjct: 169 LLKELVKYSTRLGEDCDDLQKALELMLGIPHRATDNKFISNIEGYKGNIHKLGRLLTHEW 228
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
F V ++FL++ +L CK + S +++ + K + + ++ + +
Sbjct: 229 FTVTDRE-------ARSKERYLFLFKARILVCK-VRRISEDRSVFVLKDIIRLPEVEVKD 280
Query: 630 SVKGDLRKFEVWRQGRCEVH----TITAPTVEVKRAWVERIKRVLLD 672
G+ R FE+ + + T++A VK AW++ I++ D
Sbjct: 281 HA-GEQRTFELHPKAPAGLPGYPITLSAHKDPVKAAWLKEIRQYASD 326
>UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA; n=3;
Clupeocephala|Rep: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA - Takifugu rubripes
Length = 2512
Score = 84.6 bits (200), Expect = 9e-15
Identities = 63/180 (35%), Positives = 96/180 (53%), Gaps = 18/180 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
Q LFGN+ +++ F+ ++ L+ L+ C + VA CF+ K E FF +Y+ YC N P S
Sbjct: 51 QVCALFGNIEDIYEFNSEL-LQALDLCDNDAVAVARCFIMKGE-FFEIYTQYCTNYPNSV 108
Query: 468 ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM- 524
L E + L F + Q L LPL +YLLKPVQRI KY LLL+++ ++ +
Sbjct: 109 AALTECMRKKSLATFFRERQASLKCSLPLGSYLLKPVQRILKYHLLLQEIAKHFDPEEQG 168
Query: 525 TTGLQQALDCMLVVLKCVND--SMHQIAITGVPV----------DLSQQGELLMQGSFLV 572
+++A+ M V +ND H+ AI V DL+ GEL+++G+F V
Sbjct: 169 YEVVEEAIYTMTSVAWYINDMKRKHEHAIRLQEVQSLLLNWKGPDLTTYGELVLEGTFKV 228
>UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio
"Obscurin-MLCK.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Obscurin-MLCK. - Takifugu rubripes
Length = 1948
Score = 84.2 bits (199), Expect = 1e-14
Identities = 58/231 (25%), Positives = 108/231 (46%), Gaps = 6/231 (2%)
Query: 442 VALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKP 501
VA+ + E F + Y +Y ++E F C L + + ++ +P
Sbjct: 7 VAMLLISHAENFEK-YLHYMVGQAQAEACIADKAVQQYFKVMC-LPTSPAMDVLTFIQQP 64
Query: 502 VQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-ITGVPVDLSQ 560
V+RI YQ LLK+L++ + L + M+ L +D++HQ++ I P L+
Sbjct: 65 VERIQTYQALLKELIKNKAKSGQSCCLLEKSFSMVSSLPWRSDNLHQVSLIENYPAPLTA 124
Query: 561 QGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDL 620
GE + QG F V EN +FL+++ ++ CK S N T+ FK+ +
Sbjct: 125 LGEPVRQGVFTVWEENPEVKVSSRGHQR-QVFLFKECIVLCKLKRDGSVNADTFTFKNKM 183
Query: 621 LMSQIGLTESVKGDLRKFEVWRQ--GRCEVHTITAPTVEVKRAWVERIKRV 669
++ + + ESV GD + + +W + G +T+ + VK +W++ +K +
Sbjct: 184 KLNDVEIKESVDGDEKSWGLWHEHRGSLRRYTLQGRSSLVKLSWLKDLKEL 234
>UniRef50_UPI000065DEA3 Cluster: Homolog of Brachydanio rerio
"Quattro.; n=2; Euteleostomi|Rep: Homolog of Brachydanio
rerio "Quattro. - Takifugu rubripes
Length = 413
Score = 83.0 bits (196), Expect = 3e-14
Identities = 69/220 (31%), Positives = 104/220 (47%), Gaps = 36/220 (16%)
Query: 485 QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM----TTGLQQALDCMLVVLK 540
Q+ LG K+ LA+YLLKP+QR++KY LLLKDL++ EC + L+ A D + L+
Sbjct: 86 QIELGDKMDLASYLLKPIQRMSKYALLLKDLIK--ECSQSQEQELSDLRTAEDMVKFQLR 143
Query: 541 CVNDSMHQIAITG-------------------VPVDLSQQGELLMQGSFLVVSENKXXXX 581
ND + AI G V V+L +QG+L Q F+V +
Sbjct: 144 HGNDLLAMDAIRGCDDPTKNGIVLSDAWGCLPVQVNLKEQGQLCCQDEFIVWCGRR---- 199
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +LF K K Y +K ++IG+TE+V +FE+W
Sbjct: 200 ----KYLRHVFLFEDLILFSK-TKKIEGGYDIYIYKQSFKTAEIGMTENVGDSGLRFEIW 254
Query: 642 --RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
R+ + + A + EVK W I ++L Q +G
Sbjct: 255 FRRRKSQDTFILQASSAEVKAVWTAIIGKILWRQALRNRG 294
>UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG33519-PB - Apis mellifera
Length = 1306
Score = 82.6 bits (195), Expect = 4e-14
Identities = 66/284 (23%), Positives = 128/284 (45%), Gaps = 12/284 (4%)
Query: 391 EEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKR 450
E KP + +P + D++F NL ++ FH V ++ ++ ++ F+ +
Sbjct: 49 ERYLKPLDNPDVPRAVRDNKDIIFTNLKQIADFHNTVLIEGVKYYADQPRMLGKTFL-RL 107
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
E F + YC++ P ++ + + + L L+ +L P+QRI YQL
Sbjct: 108 ERDFDKHVAYCRDEPAAQEFLQMNDVVREYFEELSQTLRDDKSLSEHLKLPIQRINDYQL 167
Query: 511 LLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGS 569
LLK+L++YS G LQ+AL+ ML + D+ I G ++ + G LL
Sbjct: 168 LLKELVKYSTRLGENCDDLQKALELMLGIPHRATDNKFISNIEGYKGNIHKLGRLLTHEW 227
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
+ V+ ++ ++FL++ +L CK + S +++ + K + + ++ + +
Sbjct: 228 YTVIDKD-------GKSKERYLFLFKARILVCK-VRRISEDRSVFVLKDIIRLPEVEVKD 279
Query: 630 SVKGDLRKFEVWRQGR-CEVHTITAPTVEVKRAWVERIKRVLLD 672
GD+R FE+ T+ A VK W+ I++ D
Sbjct: 280 H-PGDIRSFELHNPASPAYPITLIAHKDPVKAYWLREIRQYASD 322
>UniRef50_Q4SQR9 Cluster: Chromosome undetermined SCAF14531, whole
genome shotgun sequence; n=3; Clupeocephala|Rep:
Chromosome undetermined SCAF14531, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 954
Score = 82.6 bits (195), Expect = 4e-14
Identities = 74/275 (26%), Positives = 122/275 (44%), Gaps = 24/275 (8%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQ 462
P ++ G+AD LF L +FH L +E + + L CF + R+ F + YS+Y +
Sbjct: 594 PASIRGKADALFPTWTSLSSFHSHNLLPAMEGALVQSLLQQDCFSKYRDQFLQ-YSHYIR 652
Query: 463 NIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG 522
P +D+ L QA G KLPLA+ L P+ ++ L +Y E
Sbjct: 653 TKPD--------LDSPLVTQAADFFKG-KLPLASPL-SPLSFPHCLGAPVQRLEQYCEAL 702
Query: 523 SMTTGLQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKX 578
G+ A D L +L+ D I G P+ ++++G+L+ QG V +
Sbjct: 703 EELGGINPACDSALSILRHAQRHGEDLRASDLILGCPIPVAERGDLVRQGELTVCGGPRR 762
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
++FLY+ ++F K + S + Y +KH + M ++GLT+ V + KF
Sbjct: 763 KRAGVR-----NVFLYQHVLIFTKLKSP-SPGRTVYSYKHSIRMGEMGLTQDVGEEGVKF 816
Query: 639 EVWRQGRCEVH---TITAPTVEVKRAWVERIKRVL 670
EVW + T+ A + K AW + +L
Sbjct: 817 EVWVRHAARTRDCITLQAKDRDGKAAWTHDVAHLL 851
>UniRef50_A1ZBA1 Cluster: CG30115-PD, isoform D; n=4;
Sophophora|Rep: CG30115-PD, isoform D - Drosophila
melanogaster (Fruit fly)
Length = 1593
Score = 79.8 bits (188), Expect = 2e-13
Identities = 84/311 (27%), Positives = 146/311 (46%), Gaps = 35/311 (11%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
V + +LF N+ E++ F+ + L+ L +A CF++ R+ F +Y+ YC + P
Sbjct: 623 VDELQILFANIEEIYEFNS-MLLQRLINTGRDPGRIARCFIDLRDGF-DVYTTYCTSYPE 680
Query: 467 SERLRETLVD-THLF--LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
+ L L+ TH + L + Q L H+LPL +YLLKPVQRI KY LLL L ++ +
Sbjct: 681 AISLLTKLLQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKE 740
Query: 524 MTTG---LQQALDCMLVVLKCVNDSMHQIAITGV-----PVDLSQQGELLMQGSFLVVSE 575
+ ++Q + V + ++G+ +L+ GEL +G L+
Sbjct: 741 VVEAHVIMRQVAHNIDQVKRKQEQQSRVKELSGILDGWLGPELTVLGELRQEG-LLMEQH 799
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDL 635
NK + L+ ++ K TY +++L++S E + G+
Sbjct: 800 NKQRL----------VLLFATMLIITKQKEDGRLQFKTYISQNNLMLS-----EHLPGEP 844
Query: 636 RKFEV--WRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLK-ELKG-ERVRQYGLQHHR 691
F V + + R ++ +TA + KR W + IK V+L++L ++ E V Q G + R
Sbjct: 845 TSFYVIPFDEPRHQI-KLTARNRDQKRIWTQHIKGVMLEKLDIPMRAKELVYQLGNEEDR 903
Query: 692 TLIQTSSWEVS 702
T S+W+ S
Sbjct: 904 T-PDRSTWKWS 913
>UniRef50_UPI0000DA28FB Cluster: PREDICTED: similar to DEP domain
containing 2 isoform a; n=1; Rattus norvegicus|Rep:
PREDICTED: similar to DEP domain containing 2 isoform a
- Rattus norvegicus
Length = 1599
Score = 79.4 bits (187), Expect = 3e-13
Identities = 54/149 (36%), Positives = 82/149 (55%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ E+ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 64 MLFSNIEEILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLNFKDKF-RIYDEYCSNHEKA 121
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY LLLK+LL R
Sbjct: 122 QKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPR 181
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S T + +AL M V +N++ Q+
Sbjct: 182 KHSDYTAVMEALQAMKAVCSNINEAKRQM 210
>UniRef50_UPI000069EC71 Cluster: CDNA FLJ43173 fis, clone
FCBBF3007540, weakly similar to GUANINE NUCLEOTIDE
EXCHANGE FACTOR DBS.; n=1; Xenopus tropicalis|Rep: CDNA
FLJ43173 fis, clone FCBBF3007540, weakly similar to
GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS. - Xenopus
tropicalis
Length = 286
Score = 78.6 bits (185), Expect = 6e-13
Identities = 67/267 (25%), Positives = 117/267 (43%), Gaps = 24/267 (8%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
L G++ +L FH FL+DL+ C+S V+ CF++ F + ++++
Sbjct: 31 LRGSIEQLLNFHTR-FLRDLQNCVSQPLTVSYCFLQHVRYFLMFV------VATHKKIQI 83
Query: 473 TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQAL 532
+ H F Q + + L +P++++ +YQ L D+++ EC +Q+L
Sbjct: 84 FAILYHYFQQGRRRDQKEEDDSRIILQRPLEQLDQYQRFLGDMMQ--ECDQENEQERQSL 141
Query: 533 DCMLVVLKCV----NDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXX 588
++ + + + AI G VD + G LL++ F V+S K
Sbjct: 142 HTARELVSSLVPYGKNLLAVEAIRGFEVDEKEHGRLLLKDVFTVISGRK--------KSQ 193
Query: 589 XHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRC 646
H+FL++K +L K T Y +K + +GLTES + E+W RQ
Sbjct: 194 RHVFLFQKLLLLSKLKTAEG-GLENYGYKQSFKTADMGLTESATEADFRLELWFRRQKSR 252
Query: 647 EVHTITAPTVEVKRAWVERIKRVLLDQ 673
E + A + VK W I ++L DQ
Sbjct: 253 ETLVLQAESAGVKENWTNEITKLLWDQ 279
>UniRef50_Q17LU2 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 1450
Score = 77.4 bits (182), Expect = 1e-12
Identities = 71/301 (23%), Positives = 132/301 (43%), Gaps = 19/301 (6%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
V + ++LF N+ E++ F+ + L L ++ CF++ E F Y+ YC P
Sbjct: 477 VDELEILFSNIQEIWDFNSRL-LDRLNETKGDPVKISGCFIDLHENF-DCYTTYCTRYPE 534
Query: 467 SERLRETLVD---THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
+ L +L+ T+ L Q L H LPL +YLLKPVQRI KY LLL +L ++ +
Sbjct: 535 AIALLTSLLQATHTNALLIHTQKMLNHNLPLGSYLLKPVQRILKYHLLLDNLRKHCD--- 591
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+ A + M V ++ ++ +L+ + + V+ E +
Sbjct: 592 -DKQVSHAHELMKSVAHNIDQVKKKLEQQSRVKELAGIVDGWLGPDLSVLGELRQEGLLS 650
Query: 584 XXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEV--W 641
+ L++ ++ KP F+ + + L E + G+ F V +
Sbjct: 651 EHAKPRVVLLFQTMLIITKP-----KEDKRLQFRAYIPCKNLMLVEHLPGEPTSFNVIPY 705
Query: 642 RQGRCEVHTITAPTVEVKRAWVERIKRVLLD--QLKELKGERVRQYGLQHHRTLIQTSSW 699
+ ++ +TA + KR W ++IK+ +L+ + + E V Q G + R + +SW
Sbjct: 706 NDPKGQI-KLTARNRDQKRHWAQQIKQAMLEHFDIPKRAKELVLQLGDEDDRMADKNASW 764
Query: 700 E 700
+
Sbjct: 765 K 765
>UniRef50_UPI0000E463E9 Cluster: PREDICTED: similar to Cdc42 guanine
nucleotide exchange factor (GEF) 9; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Cdc42 guanine nucleotide exchange factor (GEF) 9 -
Strongylocentrotus purpuratus
Length = 1951
Score = 75.8 bits (178), Expect = 4e-12
Identities = 61/207 (29%), Positives = 102/207 (49%), Gaps = 19/207 (9%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISAT--ELVAL--CFVEKRETFFRLYSYYCQNIPRSE 468
LF N+ E++ F Q FL DLE CI L A+ CF++ + TF +Y YC N P +
Sbjct: 1621 LFCNIEEIYCFQQR-FLADLETCIDKEMPNLSAIGDCFLKYKSTF-DIYGEYCNNYPHAM 1678
Query: 469 RLRETLVDTHLFLQ---ACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+TL+ + ++Q AC+L K+ L +LL PVQ+I KY L L +LL+Y+
Sbjct: 1679 NEFQTLMRDNKYVQFFEACRLLQSMIKIQLDGFLLTPVQKICKYPLQLNELLKYTRPQHP 1738
Query: 525 T-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLVVSE-- 575
L+ AL+ M V + +N + + IA+ + + ++L + S L+ S
Sbjct: 1739 DYQPLKSALEAMREVAQSINERKRRIEHIENIALWQKTIGDWEGDDVLDRSSMLIYSNEV 1798
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCK 602
N+ +FL++ ++ C+
Sbjct: 1799 NRVSLAGRHRTSPRQLFLFDHQLIICR 1825
>UniRef50_A2A2X3 Cluster: MCF.2 cell line derived transforming
sequence-like; n=4; Euarchontoglires|Rep: MCF.2 cell
line derived transforming sequence-like - Homo sapiens
(Human)
Length = 335
Score = 75.4 bits (177), Expect = 5e-12
Identities = 34/81 (41%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Query: 613 TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+Y +K L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL
Sbjct: 11 SYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTS 70
Query: 673 QLKELKGERVRQYGLQHHRTL 693
QL+ + E + L+ ++L
Sbjct: 71 QLQACR-EASQHRALEQSQSL 90
>UniRef50_Q70Z35 Cluster: DEP domain-containing protein 2
(Phosphatidylinositol 3,4,5- trisphosphate-dependent Rac
exchanger 2) (PtdIns(3,4,5)-dependent Rac exchanger 2);
n=33; Euteleostomi|Rep: DEP domain-containing protein 2
(Phosphatidylinositol 3,4,5- trisphosphate-dependent Rac
exchanger 2) (PtdIns(3,4,5)-dependent Rac exchanger 2) -
Homo sapiens (Human)
Length = 1606
Score = 75.4 bits (177), Expect = 5e-12
Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ ++ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 72 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKF-RIYDEYCSNHEKA 129
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY L+LK+LL R
Sbjct: 130 QKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPR 189
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S + +AL M V +N++ Q+
Sbjct: 190 KHSDYAAVMEALQAMKAVCSNINEAKRQM 218
>UniRef50_UPI0000F1FC93 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1585
Score = 74.9 bits (176), Expect = 7e-12
Identities = 73/236 (30%), Positives = 111/236 (47%), Gaps = 34/236 (14%)
Query: 454 FRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F +Y+ YC N P S LR+ + + L F Q Q L H LPL YLLKPVQRI KY L
Sbjct: 295 FDIYTIYCMNYPNSVTVLRDCMKNESLVRFFQERQATLCHSLPLETYLLKPVQRILKYHL 354
Query: 511 LLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVND------------SMHQIAITGVPVD 557
LL++L + + + ++ A+ M V +ND + + + D
Sbjct: 355 LLQELSKHFDKSDPGYEVVEDAIITMTAVAWYINDMKRKQEHAIRLQEIESLLLNWTGPD 414
Query: 558 LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
LS GEL+++GSF V K FL++K +L K + +T+ F
Sbjct: 415 LSGFGELVLEGSFRVQRVKKERA----------FFLFDKMLLIAKKRL-DHFIYSTHIFC 463
Query: 618 HDLLMSQIGLTESVKGDLRKFEVWRQG-RCEVHTITAPTVEVKRAWVERIKRVLLD 672
+LL L E++K L F+V Q + H + A E KR W+ +KR++++
Sbjct: 464 CNLL-----LVENMKDPL-CFKVSDQTIPKQQHVVQAKNQEEKRLWLHYLKRLIVE 513
>UniRef50_UPI0000D575D3 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor 4 isoform b; n=2;
Endopterygota|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor 4 isoform b - Tribolium
castaneum
Length = 1627
Score = 72.5 bits (170), Expect = 4e-11
Identities = 65/224 (29%), Positives = 108/224 (48%), Gaps = 20/224 (8%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISAT----ELVALCFVEKRETFFRLYSYYCQNI 464
Q +F NL ++ F + F+KDLE I V CF++ R F ++YS YC +
Sbjct: 1267 QIKTIFINLEDILHFQAN-FVKDLEAQIDFEAPYKSCVGGCFLKHRAGF-KMYSEYCNSH 1324
Query: 465 PRSER-LRETLVDTHL--FLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
P + L+E H F +AC+L G ++PL YLL PVQRI KY L L +LL+Y+
Sbjct: 1325 PTATAALQELYQYNHYSKFFEACRLMRGLIEIPLDGYLLTPVQRICKYPLQLAELLKYTR 1384
Query: 521 CGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLVV 573
+++ALD M V +N +S+ ++A V+ + +L+ + L+
Sbjct: 1385 PDHKDYDEIKEALDAMRGVAVLINERKRRMESLEKLAAWQQRVEGWEGEDLIDSSTQLIH 1444
Query: 574 SENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
+ +FL++ +++CK K+ + TY +K
Sbjct: 1445 QGDVVKVTTGMWTNNITLFLFDHQVVYCK---KDILKRNTYVYK 1485
>UniRef50_A0NBJ0 Cluster: ENSANGP00000029817; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029817 - Anopheles gambiae
str. PEST
Length = 1684
Score = 70.1 bits (164), Expect = 2e-10
Identities = 73/281 (25%), Positives = 123/281 (43%), Gaps = 31/281 (11%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
Q VLF N+ E++ F+ + L L ++ CF++ F Y+ YC + P +
Sbjct: 577 QLKVLFSNIQEVYDFNFKL-LNRLREAKGDPVTISNCFIDLHAEFC-CYTTYCTSYPEAI 634
Query: 469 RLRETLVD---THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRY--SECGS 523
L TL+ T+ L + Q L H LPL +YLLKPVQRI KY LLL +L ++ + +
Sbjct: 635 SLLTTLLQATHTNALLVSTQKMLKHTLPLGSYLLKPVQRILKYHLLLDNLRKHCSDQQVA 694
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQI-AITGV-----PVDLSQQGELLMQGSFLVVSENK 577
+ L + + + +K D + + G+ DLS G+LL +G L S+ +
Sbjct: 695 LAHELMKKVAHNIDQVKTKLDQARLVKELAGILDGWLGPDLSVLGDLLHEGRLLEHSKPR 754
Query: 578 XXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRK 637
+ L++ ++ KP F+ + + L E + G+
Sbjct: 755 I------------VLLFQTMLIIAKP-----KEDKRLQFRAYIPCKNLMLVEHLPGEPVC 797
Query: 638 FEVWR-QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKEL 677
F V +TA E KR W ++IK+ +L ++
Sbjct: 798 FRVIPFDDPKGALQLTARNREEKRIWTQQIKKAMLQHYSDI 838
>UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 430
Score = 69.7 bits (163), Expect = 3e-10
Identities = 63/277 (22%), Positives = 126/277 (45%), Gaps = 27/277 (9%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNI 464
Q +LF N+ +++ FHQ + L+ LE C ++ F+E +E F ++YS YC N
Sbjct: 133 QIYLLFSNIEQIYEFHQKLLLQ-LEDCYLKDNPCDSMIGRVFLENKEGF-QIYSEYCNNH 190
Query: 465 PRSERLRETLVDTHL---FLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYS- 519
P + +TL +++ F +AC+L + L +LL PVQ+I KY L L +LL+++
Sbjct: 191 PHAIAELKTLCESNNYKHFFEACRLLQDMINISLDGFLLTPVQKICKYPLQLAELLKHTY 250
Query: 520 ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLVV 573
+ AL M V +N +++++IA ++ +GE +++ S ++
Sbjct: 251 PTHKDYDAVHDALRTMKEVASLINERKRKVENIYKIAKWQATIE-GWEGENVLERSSELI 309
Query: 574 SENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKG 633
FL++ +++CK N +Y + D+ + + E +G
Sbjct: 310 HSGDVHKISLGTSQERVFFLFDNQLIYCKKDILRK-NGLSYKGRIDMNSAHVTWLEDKEG 368
Query: 634 D--------LRKFEVWRQGRCEVHTITAPTVEVKRAW 662
+ ++++ + + + + + T E K W
Sbjct: 369 RAIYKNEPLVNAWKIYNETKNKWYVVYTKTAEQKERW 405
>UniRef50_Q4RXW9 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14979, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 511
Score = 69.3 bits (162), Expect = 4e-10
Identities = 32/99 (32%), Positives = 59/99 (59%), Gaps = 2/99 (2%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C++ + +A F+ K E +Y YC
Sbjct: 84 VPEDMRGKDRMVFGNIHQIYDWHKDYFLGELEKCLADPDSLAQLFI-KHERRLHMYVVYC 142
Query: 462 QNIPRSERLRETLVDTHLFLQA-CQLRLGHKLPLAAYLL 499
QN P+SE + ++T+ + A Q L +LP + L
Sbjct: 143 QNKPKSEHIVSEFIETYFEVSAPLQAALAGRLPKSKVFL 181
>UniRef50_Q54YP1 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=2; Eukaryota|Rep: Pleckstrin homology (PH)
domain-containing protein - Dictyostelium discoideum AX4
Length = 1089
Score = 69.3 bits (162), Expect = 4e-10
Identities = 97/400 (24%), Positives = 179/400 (44%), Gaps = 45/400 (11%)
Query: 306 TRSNRRNHKSTLQRKTQSLSRNQTFGNCTTTLDNFKKKTVFWKVDKTSGSKYDCLQAIY- 364
T SN N +T Q K+ + S T TTT ++ + + K K S K D +Q Y
Sbjct: 500 TNSNNNNSNTTSQTKSSTSSETTT---TTTTTESKIESPIINK--KKSDPKSDLIQRNYL 554
Query: 365 -KDYDRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTF 423
++ +++ + +++ ++ + +I+ + +L + Q +F N+ +F
Sbjct: 555 VQELLSTEKKYVNNLNRIITIFLMPLRNKIQSKDK--ILNMEEINQ---IFSNIETIFNI 609
Query: 424 HQDVFLKDLE-RCISATELVALCFV-EKRETFFRLYSYYCQNIPRSERLRETLVDTHL-- 479
H+ FL D E R + TE L V K + + Y Y S +L+ +
Sbjct: 610 HK-TFLVDFESRIENWTETSKLGDVFRKMKPYLNSYKIYSNAYNGSMLTIRSLMKSSPSF 668
Query: 480 --FLQACQLRLGHK-LPLAAYLLKPVQRITKYQLLLKDLLRYS-----ECGSMTTGLQQ- 530
FLQ C + K L L++YL+ P+QRI +Y+LLL+ +++Y+ + + G Q+
Sbjct: 669 ANFLQKCLEKPASKGLNLSSYLIMPIQRIPRYRLLLESIIKYTPTTHEDYQDLVLGNQEI 728
Query: 531 ALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG--ELLMQGSFLVVSENKXXXXXXXXXXX 588
+L M + K + +QIA + + S G E ++ + + + E
Sbjct: 729 SLSAMEIDEKL---AQYQIAHKVLDIQNSLNGLEEDIVTPTRVFLKEGDLKKISDRVVNT 785
Query: 589 XHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKG--DLRKFEVWRQ--G 644
H FL+ +++CK KN TY FK + LT VK D ++F Q
Sbjct: 786 RHFFLFNDLLIYCKKERKN-----TYRFKASFPL----LTCWVKDIPDTQRFNNLFQIIS 836
Query: 645 RCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+ + ++AP+ E K +W++ + V +D++ + E + Q
Sbjct: 837 TKKTYFLSAPSSEEKHSWMKLLNEV-IDKMVQQNPECLSQ 875
>UniRef50_Q7QGJ0 Cluster: ENSANGP00000019802; n=4; Culicidae|Rep:
ENSANGP00000019802 - Anopheles gambiae str. PEST
Length = 309
Score = 67.3 bits (157), Expect = 1e-09
Identities = 57/219 (26%), Positives = 98/219 (44%), Gaps = 9/219 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETF-FRLYSYY 460
LPP L GQ +FGN+ ++ HQ+ FL LE ++ +A F+ E F Y +
Sbjct: 35 LPPGLRGQKYHIFGNIEKIHNLHQNQFLPMLESNRASIAGIAETFIWFLENDKFYCYIMF 94
Query: 461 CQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
N P+SER+ +D F Q Q + KL L ++LL+P+QR+ +Y+LLL ++ +
Sbjct: 95 ALNRPKSERICNKNLD---FFQRRQQEVDDKLGLNSFLLQPIQRLPRYKLLLAEINKEIL 151
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGE-----LLMQGSFLVVSE 575
T L+ D + ++ K I I + ++ E L QG F + E
Sbjct: 152 KQLEDTLLESVKDEIGILCKAEKRLERFIDIVNEAMSINDIQECYEINLFSQGKFRKMFE 211
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATY 614
+FL+E++ ++ + + + Y
Sbjct: 212 VDIYDWDHRRRYPAKLFLFERSAIYAEKVKTHLEYRGRY 250
>UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein uig-1 - Caenorhabditis elegans
Length = 919
Score = 66.1 bits (154), Expect = 3e-09
Identities = 80/302 (26%), Positives = 124/302 (41%), Gaps = 33/302 (10%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
LFG + +F F++ ++ L+ ++ CFVE F Y YC N R
Sbjct: 270 LFGCIERIFAFNKQLY-NQLDAADLDCVKMSRCFVESSGKF-EDYIEYCTNYHRMMSTLY 327
Query: 473 TLVDTHLF---LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGL- 528
L L LQ QL L H L L+AYLLKPVQRI KY L L+++L+ + L
Sbjct: 328 HLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELI 387
Query: 529 --QQALDCMLVVLKCVNDSMH-----------QIAITGVPVDLSQQGELLMQGSFLVVSE 575
++A + M +ND Q + D Q L G L+
Sbjct: 388 QVKRAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLL--- 444
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV-KGD 634
+ +FL+E+ +L K A Y K ++ S + L E + +
Sbjct: 445 -EATFRQAGSKTTRLLFLFEEMLLIVK------QRGANYVCKDYIMCSNLMLNEWICPEE 497
Query: 635 LRKFEV--WRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRT 692
F+V + R + + A ++E KR W++ +KR++LD E+ +Q L T
Sbjct: 498 PLSFQVLSFDNPRAQ-YVFMASSMEQKRTWMQELKRMMLDHYSVEIPEKTKQLMLSIDNT 556
Query: 693 LI 694
I
Sbjct: 557 RI 558
>UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor 4;
n=65; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 4 - Homo sapiens (Human)
Length = 657
Score = 66.1 bits (154), Expect = 3e-09
Identities = 81/320 (25%), Positives = 148/320 (46%), Gaps = 34/320 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISA-----TELVALCFVEKRETFFRLYSYYCQN 463
Q +FGN+ +++ Q F+K LE+ + +EL A CF+E + F++YS YC N
Sbjct: 292 QLRTIFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGA-CFLE-HQADFQIYSEYCNN 348
Query: 464 IPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + E R T + ++ F +AC+L + + L +LL PVQ+I KY L L +LL+Y+
Sbjct: 349 HPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYT 408
Query: 520 ECGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ AL M V + +N +++ +IA ++ + +LL++ S L+
Sbjct: 409 HPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELI 468
Query: 573 VS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV 631
S E FL++ +++CK K+ + ++K L M + + +
Sbjct: 469 YSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLDMDGLEVVDLE 525
Query: 632 KG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
G DL F + R + H + E K+ W++ R QL + G +
Sbjct: 526 DGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSI 585
Query: 683 RQYGLQHHRTLIQTSSWEVS 702
+ LQ + ++ S +V+
Sbjct: 586 TE--LQRKQAMLNASKQQVT 603
>UniRef50_UPI000155FBE9 Cluster: PREDICTED: hypothetical protein; n=2;
Laurasiatheria|Rep: PREDICTED: hypothetical protein -
Equus caballus
Length = 1407
Score = 65.7 bits (153), Expect = 4e-09
Identities = 61/212 (28%), Positives = 103/212 (48%), Gaps = 19/212 (8%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 1034 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQHQEGF-AIYSEYCN 1091
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + +L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 1092 NHPGACAELSSLMKQGRYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 1150
Query: 518 Y-SECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSF 570
Y ++ S ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 1151 YTTQEHSDYNNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSE 1210
Query: 571 LVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
L+ S FL++ ++ CK
Sbjct: 1211 LIHSGELTRITKQGKSQQRTFFLFDHQLVSCK 1242
>UniRef50_Q96N96 Cluster: Spermatogenesis-associated protein 13;
n=29; Euteleostomi|Rep: Spermatogenesis-associated
protein 13 - Homo sapiens (Human)
Length = 652
Score = 65.7 bits (153), Expect = 4e-09
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 279 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 336
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 337 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 395
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 396 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 454
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 455 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 511
>UniRef50_Q8TCU6 Cluster: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein;
n=33; Eukaryota|Rep: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein -
Homo sapiens (Human)
Length = 1659
Score = 65.7 bits (153), Expect = 4e-09
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 98 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 152
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 153 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 212
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 213 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 244
>UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmodulin
and titin-interacting RhoGEF; n=1; Xenopus
tropicalis|Rep: obscurin, cytoskeletal calmodulin and
titin-interacting RhoGEF - Xenopus tropicalis
Length = 1922
Score = 65.3 bits (152), Expect = 6e-09
Identities = 47/183 (25%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Query: 493 PLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIA-I 551
PL YL +P+ RI +YQ+++K L+ + + A L +N+S ++ A +
Sbjct: 65 PLQHYLERPINRIQRYQVIIKKLVEERVKEVIHRQIYTA------DLSPLNNSNNKAAFL 118
Query: 552 TGVPVDLSQQGELL------MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPAT 605
+ + + Q + QG F +V E H+FL++ ++ CKP
Sbjct: 119 SSLNIATGNQNICINMNCPCFQGHF-IVWEGAPGARMAWKGHNRHVFLFKNYLIICKPKR 177
Query: 606 KNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWV 663
+ +Y FK+ + ++ I + + ++GD R FEVW R+ + + A TV +K +WV
Sbjct: 178 DTRTDTYSYVFKNMMKLTNIDINDQIEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWV 237
Query: 664 ERI 666
+ I
Sbjct: 238 KEI 240
>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
Protein vav-3 - Homo sapiens (Human)
Length = 847
Score = 64.5 bits (150), Expect = 1e-08
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein; n=4;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1223
Score = 64.1 bits (149), Expect = 1e-08
Identities = 64/211 (30%), Positives = 101/211 (47%), Gaps = 21/211 (9%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQNI 464
Q +F N+ +++ F Q FLKDLER + + CF+++ E F +YS YC
Sbjct: 850 QLKTIFSNIEDIYRF-QRKFLKDLERKYNPENPHLSEIGSCFLQQEEGF-SIYSEYCNTH 907
Query: 465 PRS----ERLRETLVDTHLFLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + +RL + H F +AC+L + + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 908 PVACAELQRLMKQSRYKHFF-EACRLLQQMIDISIAGFLLTPVQKICKYPLQLGELLKYT 966
Query: 520 -ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGE-LLMQGSFL 571
+ S G+ A M V +N +S+ IA V + L GE +L + S L
Sbjct: 967 PKDHSDFAGVCAAHKAMKNVASLINERKRRLESIDTIAHWQVAI-LHWAGEDVLARSSEL 1025
Query: 572 VVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+ S FL++ ++FCK
Sbjct: 1026 IHSGELTRIVRPGKTQQRSYFLFDHQLVFCK 1056
>UniRef50_Q4SFB4 Cluster: Chromosome 6 SCAF14605, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 6 SCAF14605, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1667
Score = 64.1 bits (149), Expect = 1e-08
Identities = 48/149 (32%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCIS----ATELVALCFVEKRETFFRLYSYYCQNIPRS 467
VLF N+ E+ H+D FL ++ + A + CF+ R F ++Y YC N ++
Sbjct: 51 VLFSNIEEILAVHRD-FLSMVDDLLQPEPHAHHEIGRCFLHFRSRF-QVYDEYCGNHEKA 108
Query: 468 ERLR---ETLVDTHLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
+RL + L C L G K +PL YL+ P+QRI KY LLL++LL R
Sbjct: 109 QRLLLELNKIRSVRTCLLNCMLLGGRKNTEVPLEGYLVAPIQRICKYPLLLRELLKRTPR 168
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S +Q++L M V +N++ Q+
Sbjct: 169 KHSDYVLVQESLQMMKAVCSSINEAKRQM 197
>UniRef50_O96035 Cluster: PEM-2; n=1; Ciona savignyi|Rep: PEM-2 -
Ciona savignyi (Pacific transparent sea squirt)
Length = 820
Score = 63.3 bits (147), Expect = 2e-08
Identities = 44/142 (30%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE---KRETFFRLYSYYCQNIPRS 467
+ LFGN+ +++ F ++ F +LE + A K + F +YS YC N P++
Sbjct: 438 NTLFGNIEDIYLFQRE-FAAELEASLDNVSTHATNIGNVFLKHKDGFCIYSEYCNNHPQA 496
Query: 468 -ERLRETLVDTHL--FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
L + L + F +AC+L + +PL +LL PVQ+I KY L L +LL+Y+ G
Sbjct: 497 VAELAQLLTNKKFMHFFEACRLLQRMIDIPLDGFLLTPVQKICKYPLQLAELLKYTHPGH 556
Query: 524 MT-TGLQQALDCMLVVLKCVND 544
++ AL+ M V + +N+
Sbjct: 557 QDYEAVKSALEAMKGVARMINE 578
>UniRef50_Q4SIP5 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 21 SCAF14577, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1228
Score = 62.5 bits (145), Expect = 4e-08
Identities = 37/93 (39%), Positives = 50/93 (53%), Gaps = 7/93 (7%)
Query: 421 FTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLF 480
FT H VF+ L + F +E +Y YCQN P+SE + +DT +
Sbjct: 193 FTAHTQVFVSGL-----LLHHLHHLFFPIQERRLNMYVLYCQNKPKSEHIVSEYIDT--Y 245
Query: 481 LQACQLRLGHKLPLAAYLLKPVQRITKYQLLLK 513
+ + +LGHKL ++ L KPVQRI KYQLLLK
Sbjct: 246 FEDLRQQLGHKLQISDLLFKPVQRIMKYQLLLK 278
>UniRef50_Q17KZ4 Cluster: Putative uncharacterized protein; n=2;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 741
Score = 62.5 bits (145), Expect = 4e-08
Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 12/128 (9%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRET-FFRLYSYY 460
LP L GQ + LFGN+ E+ HQD FL L RC E +A CF+ ET F Y Y
Sbjct: 188 LPGGLRGQRNNLFGNVEEIHELHQDDFLPALRRCYQNVEKIAQCFIHYVETGKFYCYVKY 247
Query: 461 CQNIPRSERLRETLVDTHLFLQACQLRLGHKL-----------PLAAYLLKPVQRITKYQ 509
N +S+ + E D ++ H++ L ++LL+P+QR+ +Y+
Sbjct: 248 ALNRRKSDTIFERHRDYFSVIKLLHQTSCHQIMEFIILQSNQHELNSFLLQPIQRLPRYK 307
Query: 510 LLLKDLLR 517
L L L+
Sbjct: 308 LFLDKFLK 315
>UniRef50_Q4SEL7 Cluster: Chromosome 10 SCAF14616, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF14616, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1085
Score = 62.1 bits (144), Expect = 5e-08
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 13/141 (9%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISA---TELVAL 444
GY +++P++ ++ P LV D +F + E+ H++ FLK + C++ + V
Sbjct: 78 GYMRPLKQPDSSSIVDPLLV---DEIFFQIPEILEHHEN-FLKQVAGCVAQWHDRQTVGQ 133
Query: 445 CFVEK--RETFFRLYSYYCQNIPRSERLRETLVDT----HLFLQACQLRLGHKLPLAAYL 498
++ +ET +YS Y N ++ T + H FL+ K L +
Sbjct: 134 ILIQSFSKETLANMYSAYIDNFLNAKDAVRTAKEAKPAFHKFLEQSMRENKEKQALGDLM 193
Query: 499 LKPVQRITKYQLLLKDLLRYS 519
+KPVQRI +Y+LL+KDLL+++
Sbjct: 194 IKPVQRIPRYELLVKDLLKHT 214
>UniRef50_P40995 Cluster: Rho guanine nucleotide exchange factor
scd1; n=1; Schizosaccharomyces pombe|Rep: Rho guanine
nucleotide exchange factor scd1 - Schizosaccharomyces
pombe (Fission yeast)
Length = 872
Score = 61.7 bits (143), Expect = 7e-08
Identities = 57/199 (28%), Positives = 90/199 (45%), Gaps = 15/199 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISAT---ELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F NL+E+ F Q FL LE +S + + F+ E F +Y +C N P +++
Sbjct: 271 IFTNLNEILDF-QRRFLVGLEMNLSLPVEEQRLGALFIALEEGF-SVYQVFCTNFPNAQQ 328
Query: 470 LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG-SMTTGL 528
L ++D L L L A L+KP+QRI KY LLL LL+ + G L
Sbjct: 329 L---IIDNQNQLLKVANLLEPSYELPALLIKPIQRICKYPLLLNQLLKGTPSGYQYEEEL 385
Query: 529 QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ-----QGELLMQGSFLVVSENKXXXXXX 583
+Q + C++ V VN++ ++L Q +G L L+V +
Sbjct: 386 KQGMACVVRVANQVNETRRIHENRNAIIELEQRVIDWKGYSLQYFGQLLVWD-VVNVCKA 444
Query: 584 XXXXXXHIFLYEKAMLFCK 602
H++L+EK +L CK
Sbjct: 445 DIEREYHVYLFEKILLCCK 463
>UniRef50_Q96PE2 Cluster: Rho guanine nucleotide exchange factor 17;
n=21; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 17 - Homo sapiens (Human)
Length = 2063
Score = 61.7 bits (143), Expect = 7e-08
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS---ATELVAL 444
GY + +++PEN L P+LV D +F + EL H+ FL+ + C+ A + V
Sbjct: 1091 GYMQPLKQPENSVLCDPSLV---DEIFDQIPELLEHHEQ-FLEQVRHCMQTWHAQQKVGA 1146
Query: 445 CFVEK--RETFFRLYSYYCQNIPRSE---RLRETLVDTHL-FLQACQLRLGHKLPLAAYL 498
V+ ++ +YS Y N ++ R+ + L FL+ K L+ +
Sbjct: 1147 LLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLM 1206
Query: 499 LKPVQRITKYQLLLKDLLRYS 519
+KPVQRI +Y+LL+KDLL+++
Sbjct: 1207 IKPVQRIPRYELLVKDLLKHT 1227
>UniRef50_UPI00015A61A4 Cluster: UPI00015A61A4 related cluster; n=1;
Danio rerio|Rep: UPI00015A61A4 UniRef100 entry - Danio
rerio
Length = 1018
Score = 61.3 bits (142), Expect = 9e-08
Identities = 75/277 (27%), Positives = 119/277 (42%), Gaps = 38/277 (13%)
Query: 429 LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQ 485
L+ L+ C S +A CFV+K E +F +Y+ YC N P+S L E DT F+Q
Sbjct: 4 LQCLDLCASDPVAIARCFVDKSE-YFEIYTQYCTNYPKSLACLCECTTDTRQPKFVQFHS 62
Query: 486 LRLGHK-LPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGL--QQALDCMLVV---- 538
L LP + +L +Q Y LL L + C ++ +D + +
Sbjct: 63 HPLPQTPLPRSKIILH-LQTSFTYNLLR---LNVAVCFGASSDFFYLDLIDTLYINDYSK 118
Query: 539 ----LKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLY 594
V + + I DL GEL+++G+F V + +FL+
Sbjct: 119 RADRKATVTQEVQSLLINWKGADLCTYGELVLEGTFHVQRAKERT-----------LFLF 167
Query: 595 EKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRC-EVHTITA 653
+K +L K + H Y +K + S + L ES K DL +F V + HT+ A
Sbjct: 168 DKMLLITKK--RGEH----YVYKTHISCSTLMLIESAK-DLLRFSVTHYKHPKQPHTVQA 220
Query: 654 PTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHH 690
TVE K+ W IKR++L+ + ++ + L H
Sbjct: 221 RTVEEKKLWAHHIKRLILENHHAVIPQKAKDAILDMH 257
>UniRef50_P98174 Cluster: FYVE, RhoGEF and PH domain-containing
protein 1; n=24; Euteleostomi|Rep: FYVE, RhoGEF and PH
domain-containing protein 1 - Homo sapiens (Human)
Length = 961
Score = 60.9 bits (141), Expect = 1e-07
Identities = 73/306 (23%), Positives = 132/306 (43%), Gaps = 33/306 (10%)
Query: 393 IEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKR 450
+E+ N+ P +V +F N+ ++ FHQ L +LE+ + + ++K
Sbjct: 404 LEEARNRSSFPADVVHG---IFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKL 460
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTH-----LFLQACQLRLGHKLPLAAYLLKPVQRI 505
F ++Y Y +N R+ L T + + + + L L ++L+PVQRI
Sbjct: 461 APFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRI 520
Query: 506 TKYQLLLKD-LLRYSECGSMTTGLQQALDCMLVVLKCVN------DSMHQI----AITGV 554
+Y+LLLKD LL+ + Q++L+ + + N + MH++ + G
Sbjct: 521 PRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGG 580
Query: 555 PVDL-SQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
D+ S EL+ +G L +S ++ L+ +L+C P + K +
Sbjct: 581 EEDIVSPTKELIKEGHILKLSAKN------GTTQDRYLILFNDRLLYCVPRLRLLGQKFS 634
Query: 614 YHFKHDLLMSQIGLTESVKGDL-RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+ D + + L ES +L R F V G+ + A T E K+ WV+ I LL
Sbjct: 635 VRARID--VDGMELKESSNLNLPRTFLV--SGKQRSLELQARTEEEKKDWVQAINSTLLK 690
Query: 673 QLKELK 678
+ L+
Sbjct: 691 HEQTLE 696
>UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7893-PA, isoform A - Tribolium castaneum
Length = 719
Score = 60.1 bits (139), Expect = 2e-07
Identities = 66/281 (23%), Positives = 115/281 (40%), Gaps = 26/281 (9%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+V+F +++L H F ++L R ++ F+ RE F +Y YC N+ R+ L
Sbjct: 249 EVVFYKIYDLHEIHL-AFYRELTRFRDPGFRLSSIFMNWRERFL-VYGGYCANLTRATNL 306
Query: 471 RETLVDTHLFLQACQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-----E 520
+ L D A + + L L P+QRI KY LLL+ L+ + E
Sbjct: 307 LQELCDCDENFNATIVAYEKEDNNGRFKLRDVLSVPMQRILKYHLLLEKLIENTDPNDEE 366
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDL-----SQQGELLMQGSFLVVSE 575
C + + LD + + DS H I + ++ S L+ G + E
Sbjct: 367 CNDLRRAREAMLDVAGFINEAARDSEHLAVIQNLQENIVEWYRSPDHRLVNYGRLIKDGE 426
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKP------ATKNSHNKATYHFKHDLLMSQIGLTE 629
K ++F+++K +L CK A +N N + YH D ++ L+
Sbjct: 427 MKIKAHDDQKIRNRYVFIFDKCILICKQIKVRQFAFRNIINISEYHV--DDTHNRAVLSR 484
Query: 630 SVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ F + + V+TI T+E+K+ ++ I L
Sbjct: 485 DAR-FCYHFHLVKNDNVMVYTIFVRTLELKQQMIKAINDAL 524
>UniRef50_Q54VX2 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1137
Score = 60.1 bits (139), Expect = 2e-07
Identities = 72/303 (23%), Positives = 141/303 (46%), Gaps = 29/303 (9%)
Query: 405 TLVGQADV--LFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSY 459
+L+ Q DV +FG + + + + + D+E + + ++ CF + + Y+
Sbjct: 539 SLISQEDVKFIFGGIDSISAIN-NTLMNDIESVLDKWTPYSVLGSCFTTMG-VYLKAYTD 596
Query: 460 YCQNIPRS-ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL 516
Y +N +R+ + D+ F++A + + + L + L+ PVQRI +Y LLL+DLL
Sbjct: 597 YVKNFDFGLQRICQCGKDSKFTAFIKAAEEKTVPRSRLESLLITPVQRIPRYVLLLQDLL 656
Query: 517 RYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSE 575
+++E L +AL+ + + +ND+ Q + V++ Q +L+ + LV+++
Sbjct: 657 KHTEVSHPDFPHLTKALELVKNIAMSINDTKRQSDNSLKVVEV--QNKLIGKCPNLVIAD 714
Query: 576 NK-------XXXXXXXXXXXXHIFLYEKAMLFCKPATK---NSHNKATYHFKHDLLMSQI 625
+ ++FL+ ++F KP T NS K + DL S +
Sbjct: 715 RRYVYEGYILVGDVSSKSKRVYVFLFNDILIFSKPTTNKIFNSKTKFKFLKCEDLFPSPM 774
Query: 626 GLTESVKGDL--RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
LT+ L FE+ Q E+ A T E K W+ ++++V D +++K E++
Sbjct: 775 -LTDIPNNPLWTNCFEIILQS-VEL-KFFAETPESKVVWLSQLQKVFSDIGTQQIKNEKL 831
Query: 683 RQY 685
Y
Sbjct: 832 VNY 834
>UniRef50_A2QIY3 Cluster: Complex: the S. pombe proteins scd1; n=8;
Trichocomaceae|Rep: Complex: the S. pombe proteins scd1
- Aspergillus niger
Length = 924
Score = 59.3 bits (137), Expect = 4e-07
Identities = 57/213 (26%), Positives = 97/213 (45%), Gaps = 24/213 (11%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
+F NL+ L F Q FL +E+ + E F++ E F R Y + N R +
Sbjct: 221 IFLNLNNLLDFAQR-FLIRIEQHYALPEEKQNWGELFIQHEEAF-RQYEPFIANQMRCDE 278
Query: 470 LRETLVDT-HLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
+ D H+ ++ L + L + +KP QR+TKY L+L +LL+ +E + T
Sbjct: 279 ICLRDWDKIHMAPRSKDLLQMVAQPATLNGFFVKPFQRLTKYPLMLGELLKQTENPDLRT 338
Query: 527 GLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ------------GELLMQGSFLVVS 574
+Q+A+D + VL ND++ + + DL ++ G+LL G+F V+
Sbjct: 339 DIQRAIDAIQTVLDSANDAIDKEHLQSAVKDLDERVDDWKALKIEAFGDLLRFGTFSVIK 398
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKN 607
+ HI+L+E+ +L CK N
Sbjct: 399 GDN----GKDSEREYHIYLFERILLCCKDINPN 427
>UniRef50_UPI0000EB2613 Cluster: UPI0000EB2613 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB2613 UniRef100
entry - Canis familiaris
Length = 880
Score = 58.8 bits (136), Expect = 5e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 550 AITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSH 609
A+ G DL +QG+LL + F V+ K H+FL+E +LF K
Sbjct: 694 AVRGCETDLKEQGQLLHRDPFTVICGRKKCLR--------HVFLFEHLLLFSKLKGTEGG 745
Query: 610 NKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIK 667
++ T+ +K + +GLTE++ FE+W R+ E +T+ A + E+K W I
Sbjct: 746 SE-TFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAASPEIKLKWTSSIA 804
Query: 668 RVLLDQLKELKGERVRQ 684
++L Q K RV+Q
Sbjct: 805 QLLWRQAAHNKELRVQQ 821
>UniRef50_Q4RWS9 Cluster: Chromosome 15 SCAF14981, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14981, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 912
Score = 58.8 bits (136), Expect = 5e-07
Identities = 62/239 (25%), Positives = 108/239 (45%), Gaps = 18/239 (7%)
Query: 387 SGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCI---SATELVA 443
+G E IEK L + D +F N+ +L H+ + L DL+ I +A+ L
Sbjct: 223 TGTLESIEKYFLNPLKKFISAAEIDRVFINIPDLVKVHKSL-LVDLQDSIVNKNASNLHQ 281
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLV----DTHLFLQACQLRLGH-KLPLAAYL 498
+ F+ +E +Y YC + + R + + D L L+ C R + K L L
Sbjct: 282 I-FISYKERLL-IYGIYCSQVEVAIRFLDHICKEKEDVRLKLEECSKRANNGKFTLRDLL 339
Query: 499 LKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAIT 552
+ P+QR+ KY LLL++L++++ + + L+ ALD M + + V N+++ +I
Sbjct: 340 VVPMQRVLKYHLLLQELVKHTHDATDKSNLKVALDAMKDLAQFVNEVKRDNETLREIDQY 399
Query: 553 GVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNK 611
++ Q L+ G SE + HIFL++ A++ CK N K
Sbjct: 400 QRSIENLNQ-PLMAYGRPKGDSEVRMVSSVDKRRQDRHIFLFDVAVIVCKRRGDNYEMK 457
>UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF15108, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 877
Score = 58.0 bits (134), Expect = 9e-07
Identities = 53/197 (26%), Positives = 99/197 (50%), Gaps = 16/197 (8%)
Query: 389 YKEEIEKPENQHLLPPTL---VGQADVLFGNLHELFTFHQDVFLKDLERCI---SATELV 442
Y E +E E + P T + + +F N+ +L H+ + L D++ + SA L
Sbjct: 172 YTETLESIEKHFMFPLTSYLSAAEIESVFVNIPDLVKVHKCLLL-DIQESLHHRSAQNLY 230
Query: 443 ALCFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAY 497
+ F+ +E +Y YC ++ + ++L + D + L+ C R + K L
Sbjct: 231 QI-FLNFKERLL-IYGKYCSHVETAIGTLDQLCKDREDIRMKLEECSKRANYGKFTLRDL 288
Query: 498 LLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVD 557
L+ P+QR+ KY LLL++L++++ + + L+ ALD M + + VN+ + + T +D
Sbjct: 289 LVVPMQRVLKYHLLLQELVKHTHDATDKSNLRLALDAMKDLAQYVNE-VKRDNETLREID 347
Query: 558 LSQQG-ELLMQGSFLVV 573
Q+ E L+ G FL+V
Sbjct: 348 QYQKSIENLVSGRFLLV 364
>UniRef50_Q7Z6J4 Cluster: FYVE, RhoGEF and PH domain-containing
protein 2; n=22; Theria|Rep: FYVE, RhoGEF and PH
domain-containing protein 2 - Homo sapiens (Human)
Length = 655
Score = 58.0 bits (134), Expect = 9e-07
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
V+F N+ ++ FH FL +L+R + +A + ++K F ++YS Y +N R+
Sbjct: 149 VIFSNISSIYQFHSQFFLPELQRRLDDWTANPRIG-DVIQKLAPFLKMYSEYVKNFERAA 207
Query: 469 RLRETLVDTHLFLQACQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
L T D Q R+ L L ++L+PVQRI +Y+LLLK+ ++
Sbjct: 208 ELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQ 261
>UniRef50_Q960B3 Cluster: SD09786p; n=4; Sophophora|Rep: SD09786p -
Drosophila melanogaster (Fruit fly)
Length = 592
Score = 57.6 bits (133), Expect = 1e-06
Identities = 62/291 (21%), Positives = 130/291 (44%), Gaps = 17/291 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETF-FRLYSYY 460
LP L G+ LFGN+ ++ FH+D FL L+R + + F++ + F Y +
Sbjct: 267 LPLGLRGKKYDLFGNIEQIAEFHRDEFLPMLQRNRRDLKRLFDEFLQFLDQHCFYGYVIF 326
Query: 461 CQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR--Y 518
N +S +L + + + + +L KL + ++L++P+QR+ +Y LLL + +
Sbjct: 327 TMNKQKSLKLCDLYKN---YFTSIRLERDDKLGINSFLVQPIQRMARYPLLLTQFINTFF 383
Query: 519 SECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKX 578
+ L ++ + L+ + + ++ I VD + + QG F V+E +
Sbjct: 384 KNRDIVMKPLIESCCRLEKRLRALLTTTNESEIINDIVD-CHEFNVYYQGKFRKVNEFQV 442
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+F+++K +++ + KN Y +H IG++ K +
Sbjct: 443 LDHKLKRSYRSKVFIFDKCIIYTEIKGKNLLFHGRYPCEH------IGISAKTKSFTLYY 496
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQH 689
E +Q CE TA V++ W++ I+ ++ + E + + +Y ++
Sbjct: 497 ERRKQQECE---FTADPVQI-AIWLDLIRDMINNYANEERQKLQERYSREN 543
>UniRef50_UPI0000E477CD Cluster: PREDICTED: similar to GH10341p;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to GH10341p - Strongylocentrotus purpuratus
Length = 1150
Score = 57.2 bits (132), Expect = 2e-06
Identities = 52/157 (33%), Positives = 74/157 (47%), Gaps = 20/157 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE---KRETF------------ 453
Q D LFGN+ E+ F Q FLK LE IS + KR F
Sbjct: 607 QIDALFGNIKEIIKF-QTGFLKSLEDPISKEPNFSTLDSPDEFKRILFSLGGSFLYYMEH 665
Query: 454 FRLYSYYCQNIPRSERLRETLVDTHL---FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C RS+++ + FL+A + H LA+YL+KP+QR+ KY L
Sbjct: 666 FKLYSAFCACHSRSQKILDPAKGNSALMQFLEARNPKQQHSASLASYLIKPIQRVLKYPL 725
Query: 511 LLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSM 546
LL ++ + + S L +AL M V + +ND M
Sbjct: 726 LLSEMRTHLDRDSYEHYHLSEALKGMNKVAEHINDMM 762
>UniRef50_Q16JM6 Cluster: Rho guanine exchange factor; n=2;
Culicidae|Rep: Rho guanine exchange factor - Aedes
aegypti (Yellowfever mosquito)
Length = 977
Score = 57.2 bits (132), Expect = 2e-06
Identities = 35/113 (30%), Positives = 64/113 (56%), Gaps = 7/113 (6%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+++F NL +++ F Q FL L + A + + F+E + F +YS YC + PR+
Sbjct: 486 NIIFSNLEKIWRFQQ-TFLDALRIAVPANRIGEV-FLEYQSAFM-IYSAYCNSYPRALME 542
Query: 471 RETLVDTH---LFLQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
E + L++C++ +LPL+A+LL P+QRI +Y L L +L++++
Sbjct: 543 LENYTNNKEACTILESCRVSQNLPELPLSAHLLAPIQRICRYPLHLSELVKHT 595
>UniRef50_Q9HF59 Cluster: Cdc24; n=2; Saccharomycetaceae|Rep: Cdc24
- Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 761
Score = 57.2 bits (132), Expect = 2e-06
Identities = 47/165 (28%), Positives = 83/165 (50%), Gaps = 13/165 (7%)
Query: 392 EIEKPENQHLLPPTLVGQADV--LFGNLHELFTFHQDVFLKDLE---RCISATELVALCF 446
E+ Q LL ++ ++ LF NL+E+ F Q FL LE + + + + F
Sbjct: 283 EVLSKYRQQLLENQIISSEELYMLFPNLNEIIDF-QRRFLVALEINGQVPAQAQRIGALF 341
Query: 447 VEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRIT 506
+ + FF+LY + + + D +Q+ + +G+K+ L ++LLKPVQR+
Sbjct: 342 MHSKH-FFKLYEPWSIGQNAAINFISSSFDK---MQSQEFVIGNKMELQSFLLKPVQRLC 397
Query: 507 KYQLLLKDLLRYS---ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+Y LLLKDLL+ S + T LQ AL+ + + +N++ +
Sbjct: 398 RYPLLLKDLLKLSVKTKSDVDTKELQTALEISKSIARSINENQRR 442
>UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 1; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to FYVE, RhoGEF and
PH domain containing 1 - Nasonia vitripennis
Length = 777
Score = 56.8 bits (131), Expect = 2e-06
Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 11/142 (7%)
Query: 384 LINSGYKEEIEKPENQH-LLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELV 442
LI+ ++ +++ H + PP V Q +F N+ ++ FH D L LE I A +
Sbjct: 252 LIDQIFQFRVDQENRAHPMFPPDTVQQ---MFSNIKSIYKFHNDFLLPQLETRIEAWDAD 308
Query: 443 ALC--FVEKRETFFRLYSYYCQNIPRSERLRETLVD-----THLFLQACQLRLGHKLPLA 495
++ F ++Y+ Y +N + L TL + + +L KL LA
Sbjct: 309 PRIGDIMKNFAPFLKMYTEYVKNFDYAINLISTLQQKVPRFAAIINEIQKLDECAKLSLA 368
Query: 496 AYLLKPVQRITKYQLLLKDLLR 517
++L P+QR+ +Y+LLLKD LR
Sbjct: 369 HHMLSPIQRLPRYELLLKDYLR 390
>UniRef50_Q4RP06 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 10
SCAF15009, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2108
Score = 56.4 bits (130), Expect = 3e-06
Identities = 49/155 (31%), Positives = 77/155 (49%), Gaps = 20/155 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE---KRETF------------ 453
+ + LFG+L E+ F Q VFL+ LE I+++ + K+ F
Sbjct: 1540 EMESLFGSLPEMLDF-QRVFLQTLEEKIASSPDCSTLETPAQFKKLLFSLGGSFLYYADH 1598
Query: 454 FRLYSYYCQNIPRSERLRETLVDTHLF---LQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C N + +++ E F L+A L H L +YL+KPVQR+ KY L
Sbjct: 1599 FKLYSGFCANHIKVQKVLERAKTDQAFKEFLEARNLTKQHSSTLESYLIKPVQRVLKYPL 1658
Query: 511 LLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LL++L+ ++C S L +AL M V +N+
Sbjct: 1659 LLRELVSLTDCDSEEHYHLTEALKAMEKVASHINE 1693
>UniRef50_Q17KZ0 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 956
Score = 56.0 bits (129), Expect = 3e-06
Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRET-FFRLYSYYCQNIPRSERLR 471
LFGN+ + FH+ +FL L C + +A F + E F Y Y +S+RL
Sbjct: 290 LFGNIEFIHKFHKTIFLPKLMACGKDVQKLAKVFCQYLENDSFYGYVLYALYNTKSQRLC 349
Query: 472 ETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTG 527
E L F ++ Q G KL + +++L+P+QR+ +Y++LL+++ + +G
Sbjct: 350 EQLAK---FFESQQNCSGDKLGVKSFILQPIQRLPRYKILLENIAKALRSSESVSG 402
>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
Protein vav-2 - Homo sapiens (Human)
Length = 878
Score = 56.0 bits (129), Expect = 3e-06
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 213 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 271
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 272 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 330
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 331 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 390
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+I + V L + G + G E K ++FL++K ++ CK
Sbjct: 391 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCK 438
>UniRef50_Q1ZYL3 Cluster: Rho guanine nucleotide exchange factor 4
variant 1; n=4; Eutheria|Rep: Rho guanine nucleotide
exchange factor 4 variant 1 - Homo sapiens (Human)
Length = 630
Score = 55.6 bits (128), Expect = 5e-06
Identities = 66/270 (24%), Positives = 123/270 (45%), Gaps = 26/270 (9%)
Query: 454 FRLYSYYCQNIPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQ 509
F++YS YC N P + E R T + ++ F +AC+L + + L +LL PVQ+I KY
Sbjct: 312 FQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYP 371
Query: 510 LLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQG 562
L L +LL+Y+ + ++ AL M V + +N +++ +IA ++ +
Sbjct: 372 LQLAELLKYTHPQHRDSKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGE 431
Query: 563 ELLMQGSFLVVS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLL 621
+LL++ S L+ S E FL++ +++CK K+ + ++K L
Sbjct: 432 DLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLD 488
Query: 622 MSQIGLTESVKG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD- 672
M + + + G DL F + R + H + E K+ W++ R
Sbjct: 489 MDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQV 548
Query: 673 QLKELKGERVRQYGLQHHRTLIQTSSWEVS 702
QL + G + + LQ + ++ S +V+
Sbjct: 549 QLDQETGFSITE--LQRKQAMLNASKQQVT 576
>UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin,
cytoskeletal calmodulin and titin-interacting RhoGEF,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to obscurin, cytoskeletal calmodulin and
titin-interacting RhoGEF, partial - Ornithorhynchus
anatinus
Length = 495
Score = 55.2 bits (127), Expect = 6e-06
Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 565 LMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQ 624
L QG F +V E H+FL+ ++ CKP + + Y F++ + +S
Sbjct: 47 LPQGQF-IVWEGAPGARMPWKGHKRHVFLFPNHLVICKPKRDSKTDAYGYVFRNMMKLSN 105
Query: 625 IGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
+ + + V+GD R FEVW R + + A T+ VK +WV+ I
Sbjct: 106 VDVNDQVEGDDRAFEVWHERDDSVRKYLLQARTLIVKNSWVKEI 149
Score = 35.5 bits (78), Expect = 5.3
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 622 MSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
+S + + + V+GD R FEVW R + + A T+ VK +WV+ I
Sbjct: 214 LSNVDVNDQVEGDDRAFEVWHERDDSVRKYLLQARTLIVKNSWVKEI 260
>UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1695
Score = 54.4 bits (125), Expect = 1e-05
Identities = 49/151 (32%), Positives = 70/151 (46%), Gaps = 12/151 (7%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVAL--CFVEKRETFFRLYSY 459
L T V A+VLFGN+H + + L E + + L CF E E +YS
Sbjct: 1007 LKNTKVVDAEVLFGNMHSVVETSTRL-LGSFEAALQDDKQQELGKCFAEHAEEIKSVYST 1065
Query: 460 YCQN----IPRSERLRETLVDTHLFLQACQ-LRLGHKL-PLAAYLLKPVQRITKYQLLLK 513
YC+N I E+ + L F + +R K L+++L+KPVQR+ KY LLL
Sbjct: 1066 YCKNHDDAIGLLEKYEDCLEAQEAFRKCLDAVRDTTKCWDLSSFLIKPVQRVLKYPLLLS 1125
Query: 514 DLLR---YSECGSMTTGLQQALDCMLVVLKC 541
+LL+ Y GS + M +LKC
Sbjct: 1126 ELLKVIPYKVYGSTAKCKTIRIKYMARLLKC 1156
>UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:
Protein vav-1 - Caenorhabditis elegans
Length = 1007
Score = 54.4 bits (125), Expect = 1e-05
Identities = 60/233 (25%), Positives = 103/233 (44%), Gaps = 34/233 (14%)
Query: 432 LERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRL--- 488
L C+ T + F++ R+ F Y YC N+P S +L L+ T+ F+ L
Sbjct: 322 LNECVPQT--IGEVFIKYRDQFLA-YGKYCSNLPDSRKLSNELLKTNEFISRNINELTAQ 378
Query: 489 GH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVN--- 543
G+ K + L P QR+TKY LLLK+L + ++ S L++A++ M V +N
Sbjct: 379 GNCKFGMNDLLCVPFQRLTKYPLLLKELQKKTDLASPDRKSLEEAVEVMEDVCNYINEES 438
Query: 544 ---------DSMHQ-IAITGVP--VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHI 591
D + Q I +P V L G + + G V + +I
Sbjct: 439 RDTNAIKVIDEIEQSITDLSMPLNVKLHDYGRVNLDGE---VKMAESTLTQAGKPKQRYI 495
Query: 592 FLYEKAMLFCKPATK--------NSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
FL++K ++ CK A K S T+ +K+ +MS++ + ++ D++
Sbjct: 496 FLFDKVIVVCKAANKVMAAKTTGASARTNTFTYKNAYVMSELTIDKNASLDVK 548
>UniRef50_Q54GP2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 805
Score = 54.0 bits (124), Expect = 1e-05
Identities = 36/123 (29%), Positives = 67/123 (54%), Gaps = 10/123 (8%)
Query: 405 TLVGQADV--LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSY 459
+++ Q+D+ LFGN+ L +D+ +K L+ S E + ++EK + +LY
Sbjct: 515 SIITQSDINSLFGNIEALLVISKDLLIK-LKYEFSLPEDQQRIGDLYIEKTKEM-KLYVA 572
Query: 460 YCQNIPRSERLRETLVDT--HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
Y N + + +DT F + CQ R + L + + L+ PVQRI +Y+LL +++L+
Sbjct: 573 YINNYENAMTTLKK-IDTLQPKFFKECQSRYKYSLDIGSLLIMPVQRIPRYELLFREILK 631
Query: 518 YSE 520
Y++
Sbjct: 632 YTD 634
>UniRef50_UPI0000E46C3C Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1115
Score = 53.6 bits (123), Expect = 2e-05
Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 16/232 (6%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
L++ ++++I ++H P V +++F N+ ++ FH+ L LE + E
Sbjct: 593 LLHKVFEQKIRSGNSKHKWFPNDV--INIIFSNISTIYEFHKKFLLTQLEDRMEEWEKNP 650
Query: 444 LC--FVEKRETFFRLYSYYCQNIPRSERLRET-LVDTHLF---LQACQLR-LGHKLPLAA 496
+ + F +LY+ Y N ++ + T +V F LQ Q + + L L
Sbjct: 651 CLGDILVRLSPFLKLYTDYVGNFDKAVKCLNTWMVKIPSFASLLQEIQKKPICMFLTLQH 710
Query: 497 YLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVNDSM----HQIAI 551
++L+PVQRI +Y+LLLK+ L+ S+ T ++AL + ND+M H +
Sbjct: 711 HMLEPVQRIPRYELLLKEYLKKLPAESVDRTDAERALGLISKAAHHSNDTMQTMDHFAKL 770
Query: 552 TGVPVDLSQQGELLMQGSFLVVSENKXX--XXXXXXXXXXHIFLYEKAMLFC 601
+ + GE ++ S ++ E K ++FL+ +L C
Sbjct: 771 MKLNEKIDFNGETIIDPSRRLLKEGKITRVAARSGDLLDRYLFLFNDILLCC 822
>UniRef50_Q18372 Cluster: Putative uncharacterized protein exc-5;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein exc-5 - Caenorhabditis elegans
Length = 844
Score = 53.2 bits (122), Expect = 2e-05
Identities = 43/157 (27%), Positives = 72/157 (45%), Gaps = 9/157 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L N+ L+ FH FL L I T+ +A V K+ F ++YS Y N R+ +
Sbjct: 341 LLANVSSLYQFHNTHFLPQLLESIRDWHTTKRIANV-VRKQAPFLKMYSEYTNNYDRATK 399
Query: 470 LRETLVDTHLFLQACQ----LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
L E L F + LPL +L+ PVQR+ +YQLLL++ ++ + +
Sbjct: 400 LFEELKKKKKFADVVKEIEKQAECEGLPLGHHLICPVQRVMRYQLLLQEYKKHLQPSDVD 459
Query: 526 -TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
AL+ +L N+ M ++ G +++ +Q
Sbjct: 460 FDDTTVALELVLQAAAHANEMMKKLDRFGKVIEVQEQ 496
>UniRef50_UPI000049A2CA Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 588
Score = 52.8 bits (121), Expect = 3e-05
Identities = 49/192 (25%), Positives = 92/192 (47%), Gaps = 26/192 (13%)
Query: 409 QADVLFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
Q ++F ++ +++ ++ +K E A L+ F + F++Y+ YC N
Sbjct: 202 QIKLIFSDITTIYSVNEQFLKLIKSFECQDYANVLIGQIF-NQMGPLFKMYADYCMNYHE 260
Query: 467 SERL-RETLVDTHLFLQACQLRLGH-------KLPLAAYLLKPVQRITKYQLLLKDLLRY 518
S+ L R+ + H F+ ++ K ++A+L+ PVQR+ +Y+LLL DLL+Y
Sbjct: 261 SDILIRQMEAEHHPFISWYSKQVFENASPQYKKFKISAFLITPVQRLPRYKLLLADLLKY 320
Query: 519 S-ECGSMTTGLQQALDCMLVVLKCVNDSM-----------HQIAITGVPVDL---SQQGE 563
+ C ++QAL + V VN++ +Q++IT +P D + E
Sbjct: 321 TPACHPDHENVKQALKLITEVTITVNNNTKKREMFEKMKEYQMSITNLPEDFKINNGSRE 380
Query: 564 LLMQGSFLVVSE 575
LL +G L + +
Sbjct: 381 LLAEGKVLEIKK 392
>UniRef50_Q9GTU9 Cluster: Rho guanine nucleotide exchange factor 3;
n=9; Sophophora|Rep: Rho guanine nucleotide exchange
factor 3 - Drosophila melanogaster (Fruit fly)
Length = 1011
Score = 52.8 bits (121), Expect = 3e-05
Identities = 38/110 (34%), Positives = 60/110 (54%), Gaps = 7/110 (6%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLR 471
++F N+ ++ F Q FL+ L R I + VA F++ + F YS YC PR+
Sbjct: 563 LIFSNITAIYKF-QRKFLEALRRGIEQNQ-VAKVFLKMHKGFL-CYSTYCNAYPRALIEL 619
Query: 472 ET---LVDTHLFLQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLR 517
ET + D L+ C+ +LPL+A+LL PVQRI +Y L L ++++
Sbjct: 620 ETYDRVKDARTILENCRESQNLAELPLSAHLLAPVQRICRYPLHLNEIIK 669
>UniRef50_P11433 Cluster: Cell division control protein 24; n=3;
Saccharomyces cerevisiae|Rep: Cell division control
protein 24 - Saccharomyces cerevisiae (Baker's yeast)
Length = 854
Score = 52.8 bits (121), Expect = 3e-05
Identities = 62/236 (26%), Positives = 109/236 (46%), Gaps = 26/236 (11%)
Query: 392 EIEKPENQHLLPPTLVGQADV--LFGNLHELFTFHQDVFLK-DLERCISAT-ELVALCFV 447
EI Q LL L+ ++ LF NL + F + + ++ + + + + F+
Sbjct: 298 EILDKYRQQLLDSNLITSEELYMLFPNLGDAIDFQRRFLISLEINALVEPSKQRIGALFM 357
Query: 448 EKRETFFRLYSYYC--QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRI 505
+ FF+LY + QN E L TL + ++ + + +KL L ++L KPVQR+
Sbjct: 358 HSKH-FFKLYEPWSIGQNAA-IEFLSSTLHKMRVD-ESQRFIINNKLELQSFLYKPVQRL 414
Query: 506 TKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSM-----HQIA--ITGVPVD- 557
+Y LL+K+LL S + T L+ ALD + + +N++ HQ+ + G V+
Sbjct: 415 CRYPLLVKELLAESSDDNNTKELEAALDISKNIARSINENQRRTENHQVVKKLYGRVVNW 474
Query: 558 ----LSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEK-AMLFCKPATKNS 608
+S+ GELL + + N ++L+EK +LF + TK S
Sbjct: 475 KGYRISKFGELLYFDKVFISTTN----SSSEPEREFEVYLFEKIIILFSEVVTKKS 526
>UniRef50_Q13009 Cluster: T-lymphoma invasion and metastasis-inducing
protein 1; n=31; Euteleostomi|Rep: T-lymphoma invasion
and metastasis-inducing protein 1 - Homo sapiens (Human)
Length = 1591
Score = 52.4 bits (120), Expect = 4e-05
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLE---RCISATELVALCFVEKRETF------------ 453
+ DVLFGNL E+ F + FLK LE R + E + K+ F
Sbjct: 1080 ELDVLFGNLTEMVEFQVE-FLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADR 1138
Query: 454 FRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C + + + L + DT FL A + H L +YL+KP+QRI KY L
Sbjct: 1139 FKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPL 1198
Query: 511 LLKDLLRYSECGS 523
LL++L ++ S
Sbjct: 1199 LLRELFALTDAES 1211
>UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 4 isoform 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to FYVE, RhoGEF and PH
domain containing 4 isoform 1 - Apis mellifera
Length = 729
Score = 52.0 bits (119), Expect = 6e-05
Identities = 46/175 (26%), Positives = 83/175 (47%), Gaps = 12/175 (6%)
Query: 384 LINSGYKEEIEKPENQH-LLPPTLVGQADVLFGNLHELFTFHQDVFLKDL-ERCISATEL 441
LI+ ++ +I++ H + PP V +F N+ ++ FH D L L ER +
Sbjct: 202 LIDQVFQFKIDQENRAHPMFPPETVQH---MFSNIKSIYKFHNDFLLPQLQERMQNWDSN 258
Query: 442 VALCFVEKR-ETFFRLYSYYCQNIPRSERLRETLVDTHLFLQAC-----QLRLGHKLPLA 495
+ + K F ++Y+ Y +N + L ++L A +L KL L
Sbjct: 259 PRIGDIMKNFAPFLKMYTEYVKNFDYAMNLIQSLQTKVTRFAAIIDEIQKLDECAKLSLP 318
Query: 496 AYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
++L P+QR+ +Y+LLLKD L+ +E + ++AL+ + ND+M +I
Sbjct: 319 HHMLSPIQRLPRYELLLKDYLKNLTEENADYKDTKKALELVSTAANHTNDAMKKI 373
>UniRef50_Q4SSS2 Cluster: Chromosome undetermined SCAF14347, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14347,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 650
Score = 52.0 bits (119), Expect = 6e-05
Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 10/122 (8%)
Query: 403 PPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISA-TELVALCFVEKRE-TFFRLYSYY 460
PP ++ +F N+ +++FH L DLE C+ +E L V + F R+Y+ Y
Sbjct: 85 PPEVI---KTIFSNVSSIYSFHSQFLLPDLETCLRCWSERPGLGHVLLQHGPFLRMYADY 141
Query: 461 CQNIPRSERL----RETLVDTHLFLQACQLR-LGHKLPLAAYLLKPVQRITKYQLLLKDL 515
+N ++ L E Q Q + + L L ++L+PVQRI +Y+LLLKD
Sbjct: 142 VRNFDQAVELVRVWNERSAAFRSITQDIQSQEVCGSLSLQHHMLEPVQRIPRYELLLKDY 201
Query: 516 LR 517
L+
Sbjct: 202 LK 203
>UniRef50_Q1RPY9 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 893
Score = 52.0 bits (119), Expect = 6e-05
Identities = 67/304 (22%), Positives = 127/304 (41%), Gaps = 20/304 (6%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALC--F 446
+K +E+ N++++P V +F ++ ++ FH L L+ ++ E
Sbjct: 322 HKRVMEEATNKNIMPENAVNS---IFSHVSAIYQFHHTFLLPQLKDRLANWESDPRISDI 378
Query: 447 VEKRETFFRLYSYYCQNIPRS-ERLRETLVDTHLF---LQACQ-LRLGHKLPLAAYLLKP 501
+ + F ++Y Y QN + ++ V + F +++ Q L L L ++L P
Sbjct: 379 MCRAAPFLKMYGLYVQNFDEAMNMIKAWSVKSSGFNAIIKSIQKLPECKSLTLQHHMLGP 438
Query: 502 VQRITKYQLLLKDLL-RYSECGSMTTGLQQALDCMLVVLKCVNDSMHQI----AITGVPV 556
VQRI +YQ+LL+D + R +E + AL + V N++M ++ + V
Sbjct: 439 VQRIPRYQMLLQDYVKRMAEDSPDRPDTENALKLITVAATHSNETMKKMEKFHKLVNVFN 498
Query: 557 DLSQQGELLMQGSFLVVSENK--XXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATY 614
L+ ++ S ++ E K +++L+ +L C P +
Sbjct: 499 KLADVNFDIVDVSREMLKEGKIVKISARNGEKYERYLYLFSDMLLCCTPLGRLQGKSYKV 558
Query: 615 HFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQL 674
K D+ + +TE VK +GR + A T E K AWV I+ +L +
Sbjct: 559 TAKMDI--EGMKVTE-VKNPTSPHAFCVEGRQKSTEFAASTQEEKDAWVSSIEDAILQSI 615
Query: 675 KELK 678
+ K
Sbjct: 616 ERRK 619
>UniRef50_UPI00015B5708 Cluster: PREDICTED: similar to
ENSANGP00000005626; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000005626 - Nasonia
vitripennis
Length = 1896
Score = 51.6 bits (118), Expect = 8e-05
Identities = 39/146 (26%), Positives = 74/146 (50%), Gaps = 14/146 (9%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-- 441
L+N Y ++ PEN HL+ +V D +F + + + H +VFL++L + + EL
Sbjct: 947 LVNK-YLHTLKSPENAHLVDAAIV---DEIFYQVPAILS-HHEVFLEELRKRLETWELRQ 1001
Query: 442 -VALCFVE--KRETFFRLYSYYCQNIPRSERLRETLVDTH----LFLQACQLRLGHKLPL 494
+ F+E + Y+ + N +++ +T FL+ + KL L
Sbjct: 1002 TIGDVFLEVFTKPVVLETYTLFLDNWKSAKKAIKTTCQAKPAFARFLETMEREHKGKLGL 1061
Query: 495 AAYLLKPVQRITKYQLLLKDLLRYSE 520
L+KPVQ+I +Y+LL++ LL++++
Sbjct: 1062 DQLLIKPVQKIPRYELLIQRLLKHTD 1087
>UniRef50_UPI0000F2BEF5 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor (GEF) 15,; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor (GEF) 15, - Monodelphis
domestica
Length = 834
Score = 51.6 bits (118), Expect = 8e-05
Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFV--EKRETFFRLYSYYCQNIPRSERL 470
LF N+H + + + L R S+ + LC V E F +Y Y +N E
Sbjct: 446 LFSNVHRVQSVSERFLGVLLSRVRSSPHISDLCDVVHAHAEGPFSVYVDYVRNQQYQEET 505
Query: 471 RETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG-SM 524
L++T++ A RL KLPL ++LL P QRIT+ ++LL+++ R +E G S
Sbjct: 506 YRRLMETNMRFSAELHRLQSLPQCQKLPLPSFLLLPFQRITRLRMLLQNIFRQTEEGSSR 565
Query: 525 TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
Q+AL + +++ + + ++ T + LSQ+
Sbjct: 566 RENAQRALGAISKIIERCSAEVGRMKQTEELIRLSQR 602
>UniRef50_UPI000065F5D5 Cluster: Rho guanine nucleotide exchange
factor (GEF) 17; n=1; Takifugu rubripes|Rep: Rho guanine
nucleotide exchange factor (GEF) 17 - Takifugu rubripes
Length = 1756
Score = 51.2 bits (117), Expect = 1e-04
Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 14/142 (9%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS------ATEL 441
GY +++P++ ++ P LV D +F + E+ H++ FL+ + C++
Sbjct: 799 GYMRPLKQPDSSSIVDPLLV---DEIFYQIPEILEHHEN-FLEQVAGCVAQWHDRQTVGQ 854
Query: 442 VALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDT----HLFLQACQLRLGHKLPLAAY 497
+ + V + YS Y N ++ T + H FL+ K L
Sbjct: 855 ILIQSVSRDGDNKHPYSAYIDNFLNAKDAVRTAKEAKPAFHKFLEQSMRENKEKQALGDL 914
Query: 498 LLKPVQRITKYQLLLKDLLRYS 519
++KPVQRI +Y+LL+KDLL+++
Sbjct: 915 MIKPVQRIPRYELLVKDLLKHT 936
>UniRef50_O00886 Cluster: RacGAP protein; n=2; Dictyostelium
discoideum|Rep: RacGAP protein - Dictyostelium discoideum
(Slime mold)
Length = 1335
Score = 50.8 bits (116), Expect = 1e-04
Identities = 38/152 (25%), Positives = 76/152 (50%), Gaps = 10/152 (6%)
Query: 372 EQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKD 431
E++ D+++ ++ K+ I+ P L + N LF+ H+ +
Sbjct: 1141 EEYVDSLTYIYNVFLQPIKKSIDTPNQLVSYQENLE-----ISSNFETLFSCHKTFLIAL 1195
Query: 432 LERCIS--ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTH-LF-LQACQLR 487
ER + L++ F+EK F +LY+YY QN RS ++ E ++ + LF + ++
Sbjct: 1196 KERIAEWDSKPLMSDIFMEKAG-FLKLYNYYVQNHTRSLQVLEHCIEKYSLFAIHLKRIE 1254
Query: 488 LGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
L L +P++R++KY L+L+++L+Y+
Sbjct: 1255 SDQNTELKVLLAQPLRRVSKYYLVLREILQYT 1286
Score = 36.7 bits (81), Expect = 2.3
Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
Query: 452 TFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRIT 506
+F +LY +Y N +S R + + + L + L L ++L+ P+Q +
Sbjct: 878 SFIKLYKHYVNNYDKSIRTLNQCKEKYDGFKTYMASLDYSENLSNLSLESFLVLPIQPLP 937
Query: 507 KYQLLLKDLLRYS 519
+Y +LL+DLL+Y+
Sbjct: 938 RYVMLLQDLLKYT 950
>UniRef50_P91621 Cluster: Protein still life, isoform SIF type 1; n=7;
Endopterygota|Rep: Protein still life, isoform SIF type 1
- Drosophila melanogaster (Fruit fly)
Length = 2072
Score = 50.8 bits (116), Expect = 1e-04
Identities = 48/171 (28%), Positives = 79/171 (46%), Gaps = 26/171 (15%)
Query: 399 QHLLPP----TLVGQADV--LFGNLHELFTFHQDVFLKDLERCISAT---ELVALCFVEK 449
+H L P T + A++ LFGN+HE+ TF + FL++LE + C +
Sbjct: 1460 EHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQ-FLQNLEESLDLEPDFNKFEHCGQFR 1518
Query: 450 RETF------------FRLYSYYCQNIPRSERLRETLVDTHL---FLQACQLRLGHKLPL 494
F F+LYS +C + +++++ H FL A + H L
Sbjct: 1519 NVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTL 1578
Query: 495 AAYLLKPVQRITKYQLLLKDLLRYSEC-GSMTTGLQQALDCMLVVLKCVND 544
+YL+KP+QRI KY LLL+ + ++ L +AL M V + +N+
Sbjct: 1579 ESYLIKPIQRILKYPLLLQQMRNLTDTRADEHVHLCEALKGMEKVAEHINE 1629
>UniRef50_A1ZAQ4 Cluster: CG15611-PA, isoform A; n=5;
Sophophora|Rep: CG15611-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 508
Score = 50.4 bits (115), Expect = 2e-04
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 12/223 (5%)
Query: 402 LPPTLVGQAD--VLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSY 459
LP L G+ +L GN+ E+ H+ L + R + +L L ++ F S+
Sbjct: 199 LPEALSGETKQKMLLGNIKEILELHEKEILPLMLR--NQRDLKGL--FDEFAAHFEKNSF 254
Query: 460 YCQ-NIPRSERLRETL-VDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL- 516
YC + ++ L D L+LQ Q ++ KL + ++L++P+QR+T+Y LLL+ +
Sbjct: 255 YCYVSFTMGKKSSMQLRQDNRLWLQTYQTQIKDKLGIDSFLVQPIQRLTRYPLLLQQFIS 314
Query: 517 RYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVP-VDLSQQGELLMQGSFLVVSE 575
+ + G + A+ + ++ D ++Q +P ++ + ++L G+F +E
Sbjct: 315 EFYKSGISCKPVLTAVCKLETRMRRALDVVNQ--AEEIPNIEELNELDVLQLGNFRRATE 372
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKH 618
+FL+++ ++ + K + Y+++H
Sbjct: 373 FDAQHFPTRKKYRSKVFLFDRCLVCTEVRKKRLAYRQHYNWEH 415
>UniRef50_A0CZ33 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 938
Score = 50.4 bits (115), Expect = 2e-04
Identities = 33/118 (27%), Positives = 65/118 (55%), Gaps = 7/118 (5%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALC-FVEKRETFFRLYSYYCQNIPRS 467
Q +++F NL +L+ + FL+DLE + L ++ FF++Y Y + +S
Sbjct: 115 QIEIIFNNLQQLYELNSS-FLQDLEGFLPYNRSKLLGPIIKGLAPFFKVYFPYYEGFNKS 173
Query: 468 -ERLRETLVDTHLFLQACQ----LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L++ + D F + + ++ + + ++L+KPVQRI KY LLL+DL+++++
Sbjct: 174 MATLKQCINDKEDFRKFLKNMSSIKDYNNQDIDSFLIKPVQRIPKYNLLLEDLIKHTD 231
>UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis 2;
n=16; Amniota|Rep: T-cell lymphoma invasion and
metastasis 2 - Homo sapiens (Human)
Length = 1077
Score = 50.4 bits (115), Expect = 2e-04
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 515 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 572
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 573 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 632
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 633 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 668
>UniRef50_Q4PBU1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1102
Score = 50.4 bits (115), Expect = 2e-04
Identities = 70/271 (25%), Positives = 116/271 (42%), Gaps = 32/271 (11%)
Query: 401 LLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT---ELVALCFVEKRETFFRLY 457
+LPP + LFGNL++L Q FL +E + T + F+ E F +Y
Sbjct: 307 ILPPDTLHN---LFGNLNKLVDV-QRRFLICVEENVRRTPDEQHFGHVFMTMEEDF-SVY 361
Query: 458 SYYCQNIPRSERLRETLVDTHLFL------QACQLRLGHKLPLAAYLLKPVQRITKYQLL 511
+C N + L + L + C L ++LP +++KPVQRI KY LL
Sbjct: 362 EPFCANYNLALDLINQEAHNLIRLKGMPSAEGCYLDPAYELP--TFMIKPVQRICKYPLL 419
Query: 512 LKDLL-RYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDL-----SQQGELL 565
L+ LL + S+ LQ L+ M + VN++ + +L +G +
Sbjct: 420 LEQLLKKTSDDAPRYQELQNGLEVMRRITDKVNETSRLQGNAQLVKELEFRVEDWKGHNI 479
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHDLLM 622
L++S+ H++L+EK +L CK PA + NK + LL
Sbjct: 480 KTFGLLLLSD-VFMVAKSDTEREYHVYLFEKILLCCKELAPAAQKKSNK-----NNSLLK 533
Query: 623 SQIGLTESVKGDLR-KFEVWRQGRCEVHTIT 652
+ GL + G + K + +GR ++ +T
Sbjct: 534 QKNGLGAATAGGKKPKTTLQLKGRIFINNVT 564
>UniRef50_Q4TC49 Cluster: Chromosome undetermined SCAF7053, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7053,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 481
Score = 50.0 bits (114), Expect = 2e-04
Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 454 FRLYSYYCQNIPRSERLRETLVDTHLF---LQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+ Y +C N + +++ E F L+A H L +YL+KPVQR+ KY L
Sbjct: 121 FKHYGSFCANHIKVQKVLERAKTDRAFKEFLEAKNPTNQHSSSLESYLIKPVQRLLKYPL 180
Query: 511 LLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
LL++L+ ++ GS T L +AL M V VN M QI
Sbjct: 181 LLRELVTLTQPGSPEHTHLAEALRAMEAVAAHVN-QMQQI 219
>UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2;
Entamoeba histolytica|Rep: Guanine nucleotide exchange
factor - Entamoeba histolytica
Length = 630
Score = 50.0 bits (114), Expect = 2e-04
Identities = 30/117 (25%), Positives = 63/117 (53%), Gaps = 12/117 (10%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F ++ + + ++ FL+ ++ IS + + F+ K F ++Y YC+N P + +
Sbjct: 227 IFSDIQMILSVNEQ-FLQSFQKVISQWNSESKIGGLFI-KLAPFLKIYGEYCKNYPEALK 284
Query: 470 LRETLVDTHLFLQACQLRLGHKLP-------LAAYLLKPVQRITKYQLLLKDLLRYS 519
+ + L H F + ++ + P L ++L+ P+QRI +Y+LLL DLL+++
Sbjct: 285 VLKELGSGHEFFKFYYSQIRNNAPDEYKNFELTSFLITPIQRIPRYKLLLNDLLKHT 341
>UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1067
Score = 50.0 bits (114), Expect = 2e-04
Identities = 61/273 (22%), Positives = 110/273 (40%), Gaps = 25/273 (9%)
Query: 412 VLFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS-E 468
VL GN EL F Q +F L + +++ + F++ LY YC N PR+ E
Sbjct: 393 VLCGNFEELVRFQQTLFGILDECAHLPLSSQRIGANFLQIAPQMKELYLTYCANHPRAVE 452
Query: 469 RLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTG 527
L + + F+++ L L L KP + KY LLK+L R+ E G +
Sbjct: 453 VLTKYSDELSAFIESKGAPAPGILTLTTSLSKPFCHLDKYPTLLKELERHLEDGHIDELD 512
Query: 528 LQQALDCMLVVLKCVNDSMHQ-----IAITGVPVDLSQQ-----GELLMQGSFLVVSENK 577
++A+ + N+ + +TG L Q+ G++++ FL+ +
Sbjct: 513 TKKAIPVFQNIKTSCNEMRKKKETELEILTGTIEGLDQEEINKLGDVILMAQFLIHGDE- 571
Query: 578 XXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRK 637
+ L+ ++ + K S + K+D+ + E +G L
Sbjct: 572 ------GEVRERYFLLFSSCLIILSVSAKLS--GFCFERKYDISNISVRSLEDTEGILNA 623
Query: 638 FEVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
FE+ G +V ++ K AW+E + +L
Sbjct: 624 FEIKANG--DVMKLSTNHAPEKAAWMETLPELL 654
>UniRef50_Q5JSP0 Cluster: FYVE, RhoGEF and PH domain-containing
protein 3; n=28; Euteleostomi|Rep: FYVE, RhoGEF and PH
domain-containing protein 3 - Homo sapiens (Human)
Length = 725
Score = 50.0 bits (114), Expect = 2e-04
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLFLQAC----QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>UniRef50_UPI0000DB6CBB Cluster: PREDICTED: similar to dynamin
binding protein; n=1; Apis mellifera|Rep: PREDICTED:
similar to dynamin binding protein - Apis mellifera
Length = 1021
Score = 49.6 bits (113), Expect = 3e-04
Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 15/111 (13%)
Query: 413 LFGNLHELFTFHQ---DVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
LFGNL+++ + D+ LK ++ C + + CF+E E +Y YC N +
Sbjct: 456 LFGNLYDVIQVAEELLDMILKAMKGCDEELQTIGPCFIEMNEKLKGVYVKYCGNHEAALG 515
Query: 470 LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
+ ETL + AC +++ L+KPVQRI KY L+L +L++ +E
Sbjct: 516 I-ETL----RYQIAC-------FDMSSILIKPVQRILKYPLILYELVKCTE 554
>UniRef50_UPI0000498C66 Cluster: actin-binding protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: actin-binding
protein - Entamoeba histolytica HM-1:IMSS
Length = 433
Score = 49.6 bits (113), Expect = 3e-04
Identities = 41/142 (28%), Positives = 73/142 (51%), Gaps = 11/142 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLER--C-ISATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ +F ++ VF DL + C ++ + F+ F ++Y+ YC N +
Sbjct: 156 LFSNIETVFQINK-VFCSDLIKGCCRFNSNTTIGNIFLTFIP-FLKVYNEYCSNFRHTID 213
Query: 470 LRETLVDTHLFL---QACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
L +TL H F Q + K ++ L+ PVQR+ +YQLLLKDLL++++ +
Sbjct: 214 LIKTLKYPHKFAPFYSKIQYKQSPYSKSSISDLLITPVQRLPRYQLLLKDLLKHTQQSHI 273
Query: 525 T-TGLQQALDCMLVVLKCVNDS 545
+++AL+ + V VN++
Sbjct: 274 DYNNIKKALEMIQEVANKVNET 295
>UniRef50_Q4RJT9 Cluster: Chromosome 9 SCAF15033, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF15033, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 725
Score = 49.2 bits (112), Expect = 4e-04
Identities = 60/276 (21%), Positives = 117/276 (42%), Gaps = 20/276 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ ++ FH L +L+ I+ + ++K F ++Y Y +N R+
Sbjct: 227 IFSNISSIYCFHDKFLLPELKTRITGEWDSNPRIGDILQKLAPFMKMYGEYVKNFDRAMD 286
Query: 470 LRETLVD-THLFLQACQ----LRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + F Q + L L ++L+PVQRI +Y+LLLKD L + E
Sbjct: 287 LVNTWTQRSSQFKSVVQNIQKQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEDAL 346
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQI----AITGVPVDLSQQGELLMQGSFLVVSEN-KX 578
++AL+ + N ++ ++ + V L + +++ + L+ + K
Sbjct: 347 DRKDAEKALELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIKK 406
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDL-RK 637
+++L+ +L+C P + K + + D+ ++ E+VK +L
Sbjct: 407 MSAKNGTAQDRYLYLFNNMVLYCVPKLRLMGQKFSVRERIDIAGMEV--QENVKQNLPHT 464
Query: 638 FEVWRQGRCEVHTITAPTVEVKRAWVE-RIKRVLLD 672
F + G+ + A T E K W++ RI D
Sbjct: 465 FAI--IGKQRSLELQARTAEEKEDWIQARIPHTCTD 498
>UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2;
Dictyostelium discoideum|Rep: Calmodulin-binding protein
- Dictyostelium discoideum AX4
Length = 1737
Score = 49.2 bits (112), Expect = 4e-04
Identities = 51/222 (22%), Positives = 100/222 (45%), Gaps = 20/222 (9%)
Query: 413 LFGNLHELFTFHQDVFLKDLERC---ISATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ LF+ + +V LK LE+ + V F++ + ++Y+ YC N + +
Sbjct: 1433 LFSNIEILFSINMNV-LKALEKDKDPLCENISVGQTFLDMSH-YLKMYTTYCSNQQNALK 1490
Query: 470 -LRETLVDTHLFLQACQLRLGHK----LPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
L E + F + + + LPL ++++KPVQRI KY LL+K+ ++++
Sbjct: 1491 ILEEEKIKNQPFREYLEFCMNDSVCRGLPLNSFIIKPVQRICKYPLLIKETIKFTPNDHP 1550
Query: 525 TTGLQQALDCMLV-VLKCVNDSMHQIAITGVPVDLS------QQGELLMQGSFLVV--SE 575
+ +D + +++ +N++ + + VDL + L+ QG L++ +
Sbjct: 1551 DKPALEEVDKKISDIVQSINEAKRTLELFQKIVDLQNSIDGLEDTNLMEQGRTLLMEGTV 1610
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFK 617
+ +FL+ +L C T N + A FK
Sbjct: 1611 SAVKELNSEDSLSRTLFLFNNLILICSFGT-NVLSTAINQFK 1651
>UniRef50_Q54BY9 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 667
Score = 49.2 bits (112), Expect = 4e-04
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQ 462
V + +FGN L+ + D+ + L +C S + + F+E ++ F Y+ Y
Sbjct: 329 VSEISGVFGNWERLYKINSDLLV--LIQCKLDNWSIDQTIGDLFIENTDSLFE-YTPYVT 385
Query: 463 NIPRSERLRETLVDTHL----FLQACQLRLGHK-LPLAAYLLKPVQRITKYQLLLKDLLR 517
N S +L L + FL A Q K L ++++L++P+QR+ +Y+LLL+DLL+
Sbjct: 386 NYDHSRKLLAKLTSGNTNFRNFLDAAQRDKRSKYLDISSFLIQPIQRLPRYELLLRDLLK 445
>UniRef50_O94989 Cluster: Rho guanine nucleotide exchange factor 15;
n=17; Eutheria|Rep: Rho guanine nucleotide exchange
factor 15 - Homo sapiens (Human)
Length = 841
Score = 49.2 bits (112), Expect = 4e-04
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETF--FRLYSYYCQNIPRSERL 470
LF N+ + + L R S+ + LC V F +Y Y +N E
Sbjct: 461 LFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEET 520
Query: 471 RETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG-SM 524
L+DT++ A RL +LPL ++LL P QRIT+ ++LL+++LR +E G S
Sbjct: 521 YSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSR 580
Query: 525 TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
Q+AL + +++ + + ++ T + L+Q+
Sbjct: 581 QENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQR 617
>UniRef50_UPI0000499324 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 457
Score = 48.8 bits (111), Expect = 5e-04
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 4/126 (3%)
Query: 485 QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTG-LQQALDCMLVVLKCVN 543
++ +GH L L +YL+ PVQR+ +Y+LLL+DL+R + G L+ ALD ++ + VN
Sbjct: 135 KISVGHALNLRSYLITPVQRLPRYKLLLEDLIRNTPEGHCDLARLKNALDKVMSINLNVN 194
Query: 544 DSMHQIAITGVPVDLSQ--QG-ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLF 600
S+ + ++LS+ +G + L+Q + + + + H +L+ ++
Sbjct: 195 HSVDIQSRQQKLIELSKKIKGIDDLIQPNRYYICDGELTRINQKGKKIKHFYLFNDRLIS 254
Query: 601 CKPATK 606
KP +
Sbjct: 255 GKPGNE 260
>UniRef50_Q54T65 Cluster: RhoGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RhoGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 639
Score = 48.8 bits (111), Expect = 5e-04
Identities = 44/186 (23%), Positives = 82/186 (44%), Gaps = 8/186 (4%)
Query: 392 EIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRE 451
++ EN H PP + Q +F + +F ++ + K ER + ++ L +
Sbjct: 328 KVAATENPH--PPLTLDQIHSIFSEILIIFNYNSHFYSKLDERMKENSNVLILGDLFLSI 385
Query: 452 T-FFRLYSYYCQNIPRSERLRETLV---DTHLFLQACQLRLG-HKLPLAAYLLKPVQRIT 506
T F + YS Y N ++ E + + LQ Q L L + L+ PVQR+
Sbjct: 386 TDFLKSYSVYVNNYTKAMSTLEKVKKNPNVEALLQTFQQNPACDSLDLNSLLIMPVQRVP 445
Query: 507 KYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
+Y LLL +L++ ++ + L +AL+ M V+ +N++ + D+ E
Sbjct: 446 RYILLLNELIKCTDPKNPDYENLNKALEKMKVLASVINENKREAEFLNKMYDIQNSLEGF 505
Query: 566 MQGSFL 571
+G F+
Sbjct: 506 NRGDFI 511
>UniRef50_Q54DW7 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 986
Score = 48.8 bits (111), Expect = 5e-04
Identities = 37/158 (23%), Positives = 82/158 (51%), Gaps = 9/158 (5%)
Query: 399 QHLLPPTLVGQA-DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV-EKRETFFRL 456
+++ PP L ++ ++FG++ +L + + ++ +R + + L + K + ++
Sbjct: 62 RNINPPLLSPKSIQIIFGHIEDLLSLNTELLTSIQDRMTTWYQDKRLGDIFTKMAPYLKV 121
Query: 457 YSYYCQN----IPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLL 512
Y+ YC N + R ++ + D +FL+ L L + L+ P+QRI +Y+LLL
Sbjct: 122 YTEYCGNYDKAVARLKQKSDESRDLQMFLKRVTSENSFGLDLNSLLVTPIQRIPRYKLLL 181
Query: 513 KDLLRYS--ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+ L++ + E T L +AL+ + +V +N+S+ +
Sbjct: 182 QSLIQLTPVEFSDYPT-LAKALENVALVADHINESIRE 218
>UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor 7;
n=50; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 7 - Homo sapiens (Human)
Length = 803
Score = 48.8 bits (111), Expect = 5e-04
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 315 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 373
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 374 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 425
>UniRef50_UPI000155BD3A Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 386
Score = 48.4 bits (110), Expect = 7e-04
Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
Query: 408 GQADVLFGNLHELFTFHQDVFLKDLERCISATE----LVALCFVEKRETFFRLYSYYCQN 463
G D+LF N+ ++ + L+ LE + L++ F+E RE +Y YC N
Sbjct: 154 GDLDILFSNMDDIVLVSLRL-LRGLEAAAPGSSEQLSLISNLFLELREDIEGVYRTYCVN 212
Query: 464 IPRSERLRETLVDTHLFLQACQLRLGHKLP------LAAYLLKPVQRITKYQLLLKDLLR 517
++ L E Q Q L +P L+ L+ PVQRITKY LLL+ +L
Sbjct: 213 YDQALSLVEAYKKDAGLQQGIQEVLTAVVPQAGPSGLSFLLVMPVQRITKYPLLLQKILE 272
Query: 518 YSECGSMT-TGLQQALDCMLVVLKCVND 544
Y+ GLQ+A + + +N+
Sbjct: 273 YTSPEDRAFPGLQEATAALQEINANINE 300
>UniRef50_UPI0001555442 Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 2; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to FYVE, RhoGEF and PH
domain containing 2 - Ornithorhynchus anatinus
Length = 644
Score = 48.4 bits (110), Expect = 7e-04
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSER 469
++F N+ + FH FL +L+R + + ++K F ++YS + +N R+
Sbjct: 268 LIFSNISSIHQFHSQFFLPELQRRMENWDSNPRIGDVIQKLGPFLKMYSEFVKNFDRAVE 327
Query: 470 LRETLVDT-----HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
L + + + +L L ++L+PVQR+ +Y+LLLKD +R
Sbjct: 328 LLAEWTEKCPPFQEIIANIQRSEASAQLSLQHHMLEPVQRVPRYELLLKDYIR 380
Score = 35.1 bits (77), Expect = 7.0
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 491 KLPLAAYLLKPVQRITKYQLLLKDLLR 517
+L L ++L+PVQR+ +Y+LLLKD +R
Sbjct: 439 QLSLQHHMLEPVQRVPRYELLLKDYIR 465
>UniRef50_Q5KDK5 Cluster: Protein binding protein, putative; n=2;
Filobasidiella neoformans|Rep: Protein binding protein,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1978
Score = 48.4 bits (110), Expect = 7e-04
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 4/139 (2%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLR 471
V+F N+ ++ F+ FL LE A L + Y + +S R
Sbjct: 1729 VIFANIEDILLFNTG-FLSALEERQKAARLYIDRIGDVLGFLNEAGVYMAIKLLQSLREE 1787
Query: 472 ETLVDTHL-FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQ 529
+ +D HL +QA + L L+ YLL P+QRIT+Y LL+K ++ Y+ S LQ
Sbjct: 1788 KPELDVHLKHIQATNSSI-RGLDLSHYLLIPMQRITRYPLLIKQIIAYTPYDSSDLPSLQ 1846
Query: 530 QALDCMLVVLKCVNDSMHQ 548
AL + ++ +N+S+ +
Sbjct: 1847 SALHAVERIVSRINESVRE 1865
>UniRef50_UPI0000E8080B Cluster: PREDICTED: similar to TUBA; n=3;
Gallus gallus|Rep: PREDICTED: similar to TUBA - Gallus
gallus
Length = 1180
Score = 48.0 bits (109), Expect = 0.001
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + +F + + L +LE A++ + F+ +R +Y YCQN
Sbjct: 732 LFGNIQVVISFSKQL-LSNLE----ASDSIGPVFLAQRAELENVYRVYCQNHDEAIALLE 786
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ LVD L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 787 TYEKDEKIQKLLVDLLDSLRSLYSEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 842
>UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange
factor 6 (Rac/Cdc42 guanine nucleotide exchange factor
6) (PAK-interacting exchange factor alpha) (Alpha-Pix)
(COOL-2).; n=1; Takifugu rubripes|Rep: Rho guanine
nucleotide exchange factor 6 (Rac/Cdc42 guanine
nucleotide exchange factor 6) (PAK-interacting exchange
factor alpha) (Alpha-Pix) (COOL-2). - Takifugu rubripes
Length = 664
Score = 48.0 bits (109), Expect = 0.001
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
Query: 412 VLFGNLHELFTFHQD--VFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+L GNL E+ TF Q V L++ + + + VA C++ LY YC + P +
Sbjct: 176 MLCGNLEEILTFQQGLCVALEECTKALEGQQRVAGCYLNLMSQVKTLYLAYCSSHPSAVS 235
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F+++ L L L KP R+ KY LL++L R+ E
Sbjct: 236 ILTDHSEELDKFMESQGASAPGILTLTTSLSKPFMRLDKYPTLLQELERHVE 287
>UniRef50_UPI0000ECB580 Cluster: UPI0000ECB580 related cluster; n=1;
Gallus gallus|Rep: UPI0000ECB580 UniRef100 entry -
Gallus gallus
Length = 1483
Score = 48.0 bits (109), Expect = 0.001
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + +F + + L +LE A++ + F+ +R +Y YCQN
Sbjct: 824 LFGNIQVVISFSKQL-LSNLE----ASDSIGPVFLAQRAELENVYRVYCQNHDEAIALLE 878
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ LVD L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 879 TYEKDEKIQKLLVDLLDSLRSLYSEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 934
>UniRef50_Q54SG9 Cluster: RhoGEF domain-containing protein; n=2;
cellular organisms|Rep: RhoGEF domain-containing protein
- Dictyostelium discoideum AX4
Length = 932
Score = 48.0 bits (109), Expect = 0.001
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 29/239 (12%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
+F N+ E+ + DL++ + F +K FF++YS YC + +S ++
Sbjct: 548 IFSNI-EIIRNVSKTIVDDLKQNPLTLHYCVMVF-KKMSAFFKMYSQYCTHHQKSIQVCS 605
Query: 473 TLVDTHLFLQACQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTT 526
LV ++ + + G L + YL+KP+QRI KY LL +LL+ ++ +
Sbjct: 606 ELVKSNSTFSTFKNEISSNSNGRGLSMLDYLIKPIQRICKYPLLFNELLKSTTKDDEDFS 665
Query: 527 GLQQALDCMLVVLKCVNDSMH-----------QIAITGVPVDLSQQGELLMQGSFLVVSE 575
L + ++ V + VN H Q + G P + + +++ ++ + E
Sbjct: 666 TLTEVHGKLVEVAEFVNQCQHIKENNERLLEIQNCVEGSPFPILESTRKILKECWVRIKE 725
Query: 576 NKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSH--NKATYHFKHDLLMSQIGLTESVK 632
K +IFL+ ++F TKNS K Y + L L SVK
Sbjct: 726 GK----NDNDNHNRYIFLFNDNIMF----TKNSSFTKKYQYQYSFSLPYHSTKLLPSVK 776
>UniRef50_A0C114 Cluster: Chromosome undetermined scaffold_140,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_140,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 891
Score = 48.0 bits (109), Expect = 0.001
Identities = 33/115 (28%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV-EKRETFFRLYSYYCQ--NIP 465
Q+ +LF NL +++ ++ + ER + T+ + +K FF++Y Y +I
Sbjct: 86 QSKLLFRNLKQIYLLNKQFLFEISERFSNFTQHTCFGKIFDKYVQFFKIYFEYTSGFSIE 145
Query: 466 RSERLRETLVDTHLFLQACQ-LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
LR+ + + F+ + + L +YL+KPVQR+ KY LLLKDL++++
Sbjct: 146 VVSSLRKEIPKLNDFISELEEADIFKGGNLESYLIKPVQRLPKYVLLLKDLIKHT 200
>UniRef50_UPI0000F1F644 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 841
Score = 47.6 bits (108), Expect = 0.001
Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 9/113 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L DLE+ + ++T + ++K F ++Y+ Y +N +
Sbjct: 316 IFSNITSINAFHSQFLLPDLEKRMGEWTSTPRIG-DILQKLTPFLKMYAEYVRNFDHAMD 374
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDLLR 517
L + +D +A L + + L L ++L+PVQR+ +Y++LLKD L+
Sbjct: 375 LLKQWIDRSPPFKAIILDIQSQEVCGNLTLQHHMLEPVQRVPRYEMLLKDYLK 427
>UniRef50_UPI0000F1DCF3 Cluster: PREDICTED: hypothetical protein; n=1;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1384
Score = 47.6 bits (108), Expect = 0.001
Identities = 47/141 (33%), Positives = 69/141 (48%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRS-----E 468
L +L+ ++D+ LK+LE + S + +A FV+K + ++YS Y + R+ E
Sbjct: 872 LPQLYELNKDL-LKELEERVAHWSDHQRLADIFVQKGP-YLKMYSTYIREFDRNVALLDE 929
Query: 469 RLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ R+ + + Q L L YLLKPVQRI +YQLLL D L+ E S
Sbjct: 930 QCRKNPPFSSVVRQFETSPRCASLALKHYLLKPVQRIPQYQLLLTDYLKNLPEDSSDYKD 989
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL + V ND M Q
Sbjct: 990 TQTALSVVKEVANHANDIMKQ 1010
>UniRef50_Q5RH33 Cluster: Novel protein similar to human and mouse
FYVE, RhoGEF and PH domain containing 6; n=3; Danio
rerio|Rep: Novel protein similar to human and mouse
FYVE, RhoGEF and PH domain containing 6 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 1315
Score = 47.6 bits (108), Expect = 0.001
Identities = 47/141 (33%), Positives = 69/141 (48%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRS-----E 468
L +L+ ++D+ LK+LE + S + +A FV+K + ++YS Y + R+ E
Sbjct: 823 LPQLYELNKDL-LKELEERVAHWSDHQRLADIFVQKGP-YLKMYSTYIREFDRNVALLDE 880
Query: 469 RLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ R+ + + Q L L YLLKPVQRI +YQLLL D L+ E S
Sbjct: 881 QCRKNPPFSSVVRQFETSPRCASLALKHYLLKPVQRIPQYQLLLTDYLKNLPEDSSDYKD 940
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL + V ND M Q
Sbjct: 941 TQTALSVVKEVANHANDIMKQ 961
>UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing
protein 4; n=34; Amniota|Rep: FYVE, RhoGEF and PH
domain-containing protein 4 - Homo sapiens (Human)
Length = 766
Score = 47.6 bits (108), Expect = 0.001
Identities = 49/271 (18%), Positives = 117/271 (43%), Gaps = 16/271 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSERL 470
+F N+ + FH L +LE+ + E ++K F ++Y Y + + L
Sbjct: 253 IFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMEL 312
Query: 471 RETLVDT-----HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + + + + ++ L L ++L+PVQRI +Y++LLKD LR S+
Sbjct: 313 VKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLD 372
Query: 526 -TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ---QGELLMQGSFLVVSENK--XX 579
+++L+ + N ++ ++ +++ + + E ++ S ++ E +
Sbjct: 373 WNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKL 432
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
++FL+ +L+C P +K T + + +I T++ + F+
Sbjct: 433 AARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYP-HTFQ 491
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
V G+ + A + + K W++ ++ +
Sbjct: 492 V--SGKERTLELQASSAQDKEEWIKALQETI 520
>UniRef50_UPI0000499563 Cluster: 158792 GrfA protein; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: 158792 GrfA protein -
Entamoeba histolytica HM-1:IMSS
Length = 1012
Score = 47.2 bits (107), Expect = 0.002
Identities = 40/135 (29%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLV-DTHL--FLQACQLRLG--HKLPLAAYLLKPVQ 503
K FF +Y + N ++ L L DT L +L++CQ + L L YL+ PVQ
Sbjct: 460 KFSPFFIVYRNFLINHNKAFTLLTKLEEDTKLERYLESCQTQFNTNQNLDLRDYLIMPVQ 519
Query: 504 RITKYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
R+ +Y LLL DLL+++ + +AL+ M V VN+S+ +DL +
Sbjct: 520 RLPRYSLLLTDLLKHTPTNHCDYQNITKALEAMKEVTTKVNESISTNQQQQKLIDL--RS 577
Query: 563 ELLMQGSFLVVSENK 577
+L + F V+ ++
Sbjct: 578 KLAQRNDFEVIEPHR 592
>UniRef50_Q4SFX7 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1982
Score = 47.2 bits (107), Expect = 0.002
Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 454 FRLYSYYCQN---IPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F++YS +C + +P+ +T D FL R H L +YL+KP+QR+ KY L
Sbjct: 1490 FKIYSAFCASHTKVPKVLAKAKTDSDFKTFLAERNPRQQHSSTLESYLIKPIQRVLKYPL 1549
Query: 511 LLKDL 515
LLK+L
Sbjct: 1550 LLKEL 1554
>UniRef50_UPI00006A1ACD Cluster: FYVE, RhoGEF and PH
domain-containing protein 4 (Actin filament- binding
protein frabin) (FGD1-related F-actin-binding protein)
(Zinc finger FYVE domain-containing protein 6).; n=4;
Euteleostomi|Rep: FYVE, RhoGEF and PH domain-containing
protein 4 (Actin filament- binding protein frabin)
(FGD1-related F-actin-binding protein) (Zinc finger FYVE
domain-containing protein 6). - Xenopus tropicalis
Length = 579
Score = 46.4 bits (105), Expect = 0.003
Identities = 54/273 (19%), Positives = 116/273 (42%), Gaps = 16/273 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRS-ER 469
+F N+ + +FH L +LE + + ++K F ++Y+ Y +N + E
Sbjct: 48 IFSNISSIQSFHGQFLLPELESRMKEWSISPKIGDILQKLAPFLKMYAEYVKNFDNAMET 107
Query: 470 LRETLVDTHLFLQACQ--LRLGH--KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM- 524
LR + + F + R G L L ++L PVQRI +Y++LLKD LR S+
Sbjct: 108 LRGWMEKSVQFKNVVEEIQREGKCGNLTLQHHMLGPVQRIPRYEMLLKDYLRKLPADSLD 167
Query: 525 TTGLQQALDCMLVVLKCVNDSMHQI----AITGVPVDLSQQGELLMQGSFLV-VSENKXX 579
++AL+ + N ++ ++ + + L ++ +++ + L+ +
Sbjct: 168 RKDAEKALELISFAATHSNTAIRKMENLKKLLSIYEMLGEEEDIVHPSNELIKEGQILKL 227
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
++FL +L+C P K T K L ++ T++ + F+
Sbjct: 228 AARNTSAQERYLFLLNNMLLYCVPKFSLVGTKYTLRTKIGLEGMKVVETQN-EDYPHTFQ 286
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+ G+ + A + + K W++ ++ + +
Sbjct: 287 I--SGKERTLELQASSEQNKEEWIKALRDTIAE 317
>UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1253
Score = 46.4 bits (105), Expect = 0.003
Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 14/192 (7%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVNDSMHQI- 549
LPL A+LLKP QR+ Y+ LL+ LL+Y S + +Q AL+ ++ +K +SM ++
Sbjct: 833 LPLNAFLLKPSQRLLHYRFLLERLLKYCVRDSEDSQDIQGALEELVGAVKSTEESMKKLE 892
Query: 550 ---AITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLF-CKPAT 605
I + DL L+ QG + E FL+ +L+ CK T
Sbjct: 893 NFQKIIELQRDLIGVDNLVQQGREF-IREGCLQKMTRKGPQPRMFFLFSDLLLYTCKGVT 951
Query: 606 KNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVH-TITAPTVEVKRAWVE 664
+ + + + + + L E +L + H T+ AP+ E K W+E
Sbjct: 952 LTNQ----FRVRGQIPLHTVKL-EDTGPELHGLFPFNINFSNKHMTVAAPSEEEKYKWLE 1006
Query: 665 RIKRVLLDQLKE 676
+ +V++ Q KE
Sbjct: 1007 DL-QVVVRQAKE 1017
>UniRef50_UPI000049A4D9 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 730
Score = 46.0 bits (104), Expect = 0.004
Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Query: 391 EEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFL--KDLERCISATELVALCFVE 448
+E++ +NQ ++P V D++F + E+ +++ FL K L+ + F +
Sbjct: 33 KEMKSEKNQSIIPSEDV---DIIFEHYDEVLNINKNFFLALKKLQETHKIETHLGQIF-K 88
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQAC-----QLRLGHKLPLAAYLLKPVQ 503
FF++Y Y + S ++ F + Q+ L L +YL+ PVQ
Sbjct: 89 LFTPFFKVYFLYISHYDDSNQVLTEYEKNPKFNELLASLQTQIPTTTNLDLRSYLIMPVQ 148
Query: 504 RITKYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
R+ +Y+LLLKDLL+ ++ L ++L+ + V VN+ I
Sbjct: 149 RLPRYELLLKDLLKNTKSDHPDYAALTESLNGIRAVTMEVNERTKDI 195
>UniRef50_Q4SCD4 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14659,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 787
Score = 46.0 bits (104), Expect = 0.004
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 484 CQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSECGSMTTGLQQALDCMLVVL 539
C L G K +PL YLL P+QRI KY LLLK+LL R + + +++AL M V
Sbjct: 51 CMLLGGKKSTDIPLEGYLLTPIQRICKYPLLLKELLKRTPKKHADYPAVEEALQAMKAVC 110
Query: 540 KCVNDSMHQI 549
+N++ Q+
Sbjct: 111 SNINETKRQM 120
>UniRef50_Q86HN1 Cluster: Similar to PH (Pleckstrin homology) domain
[Caenorhabditis elegans]; n=2; Dictyostelium
discoideum|Rep: Similar to PH (Pleckstrin homology)
domain [Caenorhabditis elegans] - Dictyostelium
discoideum (Slime mold)
Length = 1165
Score = 45.6 bits (103), Expect = 0.005
Identities = 44/201 (21%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS-ATELVALCFVEKRETFFRLYSYYCQNIPRS-ERL 470
+F N+ + F +++ +KD+++ +E VA F+ K + LY Y N E L
Sbjct: 163 IFSNIESIKDFSEEL-IKDMKKKFEDGSEDVATPFILKEKQVRELYIPYATNHANLVEGL 221
Query: 471 RETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + Q Q + KL L ++L+ PVQR+ +YQ+L ++L+++E
Sbjct: 222 SKMIEKRPMLAQFLQQVKENPLNKSKLDLPSFLIMPVQRMVRYQMLFNEILKHTEKEHTD 281
Query: 526 -TGLQQALDCMLVVLKCVNDSM--HQ--IAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
L++A +++ + +N+ + HQ + + + +L G +++ + + V E
Sbjct: 282 YQRLEEATQMSMLITRTINEQIRRHQNLLKVQEIQSNLI-GGPKIIKENRVFVREGGLMK 340
Query: 581 XXXXXXXXXHIFLYEKAMLFC 601
FL+ A+++C
Sbjct: 341 VCRKEDKFRWFFLFSDALMYC 361
>UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4;
Entamoeba|Rep: Guanine nucleotide exchange factor -
Entamoeba dispar
Length = 571
Score = 45.6 bits (103), Expect = 0.005
Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 16/118 (13%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFR--------LYSYYCQN 463
++FGN+ ++ +H F +LE+C+S L F+ + + LY Y N
Sbjct: 289 IIFGNIIDIEKYHHK-FSNELEKCLSLCNEEKLEFISFSDILLKYFTPSMLDLYCKYANN 347
Query: 464 IP----RSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
+ + L T VD ++ + GH +P ++L++P+QRI +Y LLL+ L++
Sbjct: 348 VDIGMAKFNELSRTDVDVGCIVKELSSK-GHYVP--SFLIQPIQRIPRYVLLLESLIK 402
>UniRef50_A0CQC8 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_24,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1153
Score = 45.6 bits (103), Expect = 0.005
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 454 FRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLP------LAAYLLKPVQRITK 507
F+ Y YC+ S+++R+ +T+ + + L P + +YL+KPVQR+ K
Sbjct: 357 FKFYYDYCKEFDASKKMRDNYANTNQVYKKFFMDLKKNNPQLSNLDVESYLIKPVQRLPK 416
Query: 508 YQLLLKDLLRYS 519
Y LL KDLL+++
Sbjct: 417 YILLYKDLLKHT 428
>UniRef50_Q4PGM7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1592
Score = 45.6 bits (103), Expect = 0.005
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
Query: 480 FLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTG--LQQALDCML 536
F++ C+ H +L + +YLL PVQRI +Y+LLL+DL++ ++ + G L AL+ +
Sbjct: 1361 FMKRCRTHPRHAQLNVESYLLLPVQRIPRYRLLLEDLVKSTDPSRLADGDALATALEHVT 1420
Query: 537 VVLKCVNDSMHQ 548
+ VN+S Q
Sbjct: 1421 QIASKVNESKRQ 1432
>UniRef50_A5DJC8 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 718
Score = 45.6 bits (103), Expect = 0.005
Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 13/170 (7%)
Query: 391 EEIEKPENQ-HLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT---ELVALCF 446
E + K +N+ L L Q D++F NL ++ T Q FL LE + + + + L F
Sbjct: 292 ELLLKYKNEVRLADSVLPEQLDIMFPNL-DVITDFQRRFLNGLECNVGISYKYQRIGLAF 350
Query: 447 VEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRIT 506
+ FR Y + I ++ + E L L+ + L +Y+LKPVQR+
Sbjct: 351 LHAARGPFRAYEPW--TIGQTAAV-ELLHREGASLRKSSSLIDPGFELHSYVLKPVQRLC 407
Query: 507 KYQLLLKDLLRYSECGSMTTGLQQ---ALDCMLVVLKCVNDSMHQIAITG 553
KY LLLK+L++ ++ G ++ AL+ M V VN++ + G
Sbjct: 408 KYPLLLKELVK--STSTLNPGYEELTLALEAMKEVAHKVNEAQRRAENVG 455
>UniRef50_Q8N5V2 Cluster: Ephexin-1; n=32; Euteleostomi|Rep:
Ephexin-1 - Homo sapiens (Human)
Length = 710
Score = 45.6 bits (103), Expect = 0.005
Identities = 47/191 (24%), Positives = 95/191 (49%), Gaps = 13/191 (6%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA-LCFVEKRET--F 453
EN+ + +A +LF N+ ++ + FL +LE + +++ +C + R
Sbjct: 301 ENERIRKILHPSEAHILFSNVLDVLAVSER-FLLELEHRMEENIVISDVCDIVYRYAADH 359
Query: 454 FRLYSYYCQNIPRSERL-RETLVDTHLFLQA-CQLRLGHK---LPLAAYLLKPVQRITKY 508
F +Y Y N ER ++ L + F + QL L K LP +++L+ P QRIT+
Sbjct: 360 FSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRL 419
Query: 509 QLLLKDLLRYSECGS--MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
+LL++++L+ E S T L + +VV C N+ + +++ T + + ++ E +
Sbjct: 420 KLLVQNILKRVEERSERECTALDAHKELEMVVKAC-NEGVRKMSRTEQMISIQKKMEFKI 478
Query: 567 QGSFLVVSENK 577
+ S ++S ++
Sbjct: 479 K-SVPIISHSR 488
>UniRef50_Q6ZV73 Cluster: FYVE, RhoGEF and PH domain-containing
protein 6; n=18; Eumetazoa|Rep: FYVE, RhoGEF and PH
domain-containing protein 6 - Homo sapiens (Human)
Length = 1430
Score = 45.6 bits (103), Expect = 0.005
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 925 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 982
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 983 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 1042
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 1043 TQDALAVVIEVANHANDTMKQ 1063
>UniRef50_UPI0000E494A0 Cluster: PREDICTED: similar to FGD6 protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to FGD6 protein - Strongylocentrotus purpuratus
Length = 499
Score = 45.2 bits (102), Expect = 0.007
Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQA-DVLFGNLHELFTFHQDVFLKDLERCI---SAT 439
L+N ++ I++ ++ P + A D + G+L L F++ L DLE I S T
Sbjct: 19 LLNVDLRQVIDEGSKKNGGKPVIEKAALDQIVGHLPHLQMFNE-CLLTDLETRIRNWSTT 77
Query: 440 ELVALCFVEKRETFFRLYSYYCQNIPR-----SERLRETLVDTHLFLQACQLRLGHKLPL 494
+A F+ K F +LYS Y + R + + V T + + L +
Sbjct: 78 PKIADIFLTKGH-FLKLYSTYILDFERITAAFDDACNKNPVFTQVVKEFEMSERCRSLAI 136
Query: 495 AAYLLKPVQRITKYQLLLKDLLRYSECGS 523
Y+LKPVQRI +Y++LL D L+ + S
Sbjct: 137 KHYMLKPVQRIPQYKMLLTDYLKQLDADS 165
>UniRef50_Q1RMS9 Cluster: FGD6 protein; n=11; Amniota|Rep: FGD6
protein - Bos taurus (Bovine)
Length = 1092
Score = 45.2 bits (102), Expect = 0.007
Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE +S + +A FV K+ + ++YS Y + ++ L +
Sbjct: 587 LPQLYELNRDL-LKELEERMSNWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 644
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 645 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSGDYRD 704
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 705 TQDALAVVIEVANHANDTMKQ 725
>UniRef50_A0D0E6 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 544
Score = 45.2 bits (102), Expect = 0.007
Identities = 38/136 (27%), Positives = 70/136 (51%), Gaps = 17/136 (12%)
Query: 393 IEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEK 449
++ + LLP + +A F N+ +++ ++ FL++L++ + V F+ K
Sbjct: 105 VKNVKEMKLLPENEIQKA---FSNISQIYDLNK-TFLRELQKKLEFYHNNVCVGQIFL-K 159
Query: 450 RETFFRLYSYYCQ--NIPRSERLRETLVDTHLFL----QACQLRLGHKLPLAAYLLKPVQ 503
FF++Y Y Q NI + LR D FL +AC + G L ++L+KPVQ
Sbjct: 160 YIPFFKMYFQYLQEFNIDQISILRNQYQDFDNFLKNLEEACVFKGGD---LNSFLIKPVQ 216
Query: 504 RITKYQLLLKDLLRYS 519
R+ +Y LL+ +++Y+
Sbjct: 217 RLPRYSLLITSVVKYT 232
>UniRef50_A0BKK3 Cluster: Chromosome undetermined scaffold_112,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_112,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1168
Score = 45.2 bits (102), Expect = 0.007
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 413 LFGNLHELFTFHQD--VFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
LF N+ ++ Q+ + KDL++ A+ + FF++Y Y N + +L
Sbjct: 189 LFSNIQSIYLLSQETLILFKDLQKDYHQEYQNAIKQLLSHANFFKIYQDYLINYANAIKL 248
Query: 471 RETLVDTHL----FL-QACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
+ L + FL QA + LG L YL+ PVQRI KY LL KD L+
Sbjct: 249 QTNLRHNNKQYKSFLDQADKKNLGKTLE-NYYLILPVQRIPKYVLLFKDYLK 299
>UniRef50_A4R6Z2 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1127
Score = 45.2 bits (102), Expect = 0.007
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 20/213 (9%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC---FVEKRETFFRLYSYYCQNIPRSER 469
+FGN+ + F Q FL +E S V FV +F +Y+ + N ++
Sbjct: 361 IFGNIDAILDF-QRRFLIRVETTNSMPGEVQQWGSPFVAMEASFDPIYTPFIANQRKAAL 419
Query: 470 LRETLVDTHLFLQ---ACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
+ ++ D ++ AC L +LLKP+QR+ KY LLLKDLL+ SE +
Sbjct: 420 IAQSEFDKIKSIEHPVACDFNT-----LDGFLLKPMQRLVKYPLLLKDLLKKSEDDKVKD 474
Query: 527 GLQQALDCMLVVLKCVNDSMHQIAITGVPVDLS------QQGELLMQGSFLVVSENKXXX 580
L + L+ N+++ + + DL + ++ GS L+ +
Sbjct: 475 DLSLGIAAAERTLQKANEAVDRDLLDDALEDLKTRVDDWKNHQVDQFGSLLLHGVHTVLT 534
Query: 581 XXXXXXXXXHIFLYEKAMLFCK--PATKNSHNK 611
I+L+E +L CK +TK+ K
Sbjct: 535 GKSESERDYEIYLFECILLCCKEISSTKSKDKK 567
>UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=7; Clupeocephala|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 974
Score = 44.8 bits (101), Expect = 0.009
Identities = 38/116 (32%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATEL---VALCFVEKRETFFRLYSYYCQNIPRSE 468
++ GNL E+ TF Q + ++ LE C E V F+ LYS YC N P +
Sbjct: 404 LILGNLEEICTFQQ-MLVQSLEECTKLPETQQRVGGFFLNLMPQMRALYSSYCSNHPSAV 462
Query: 469 RL----RETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
+ E L D F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 463 NVLTQQSEVLGD---FMEGRGAVSPGILTLTTGLSKPFMRLDKYPTLLKELERHME 515
>UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=2; Dictyostelium discoideum|Rep: Pleckstrin
homology (PH) domain-containing protein - Dictyostelium
discoideum AX4
Length = 1145
Score = 44.8 bits (101), Expect = 0.009
Identities = 39/148 (26%), Positives = 71/148 (47%), Gaps = 9/148 (6%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISA--TELVALCFVEKRETFFRLYSYYCQNIPRSE- 468
++F N+ L ++++ L++ V CF+ + + ++YS YC N S
Sbjct: 498 IIFSNIQLLLNVNKELLSDLLQKAPDEKPNHTVGTCFIYFFK-YLKIYSGYCANQTISAD 556
Query: 469 ---RLRETLVDTHLFLQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGS 523
R + + FL+ Q + L ++L+KPVQR+ KY LLL++L++ S E
Sbjct: 557 HIARCSKKIPSFKQFLEEKQASTECRQCNLESFLIKPVQRLCKYPLLLRELIKNSCEGHP 616
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAI 551
L++A + V+ VN+S + I
Sbjct: 617 DLANLEKAYTEIQEVVLSVNESKRKAEI 644
>UniRef50_Q9NHV9 Cluster: Protein vav; n=6; Diptera|Rep: Protein vav
- Drosophila melanogaster (Fruit fly)
Length = 793
Score = 44.8 bits (101), Expect = 0.009
Identities = 67/278 (24%), Positives = 114/278 (41%), Gaps = 28/278 (10%)
Query: 364 YKDYDRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTF 423
++ D + + DT S ++ + K + P +HL L ++F + EL
Sbjct: 214 FEQRDYVIRELIDTESNYLDVLTA-LKTKFMGPLERHLNQDEL----RLIFPRIRELVDI 268
Query: 424 HQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRS-ERLRETLVDTHLF 480
H FL L ++ V + F++ RE F +Y +C + + + L + +
Sbjct: 269 HTK-FLDKLRESLTPNAKVKMAQVFLDFREPFL-IYGEFCSLLLGAIDYLADVCKKNQII 326
Query: 481 ---LQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGLQQALDCM 535
+Q C+ KL L L P+QRI KY LLL L++ S L++A + M
Sbjct: 327 DQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAM 386
Query: 536 LVVLKCVN----DSMHQIAITGV-----PVDLSQQG---ELLMQGSFLVVSENKXXXXXX 583
+ V + +N DS H + I V + L Q G +LL G L+ E
Sbjct: 387 IDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHED 446
Query: 584 XXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDL 620
+ F+++K ++ K K + TY H+L
Sbjct: 447 QKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNL 484
>UniRef50_UPI00015B49F8 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1279
Score = 44.0 bits (99), Expect = 0.015
Identities = 33/145 (22%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIP 465
+A ++FGN ++ H+ + L++L C S + F++ + Y Y
Sbjct: 841 EAKIIFGNFPPIYEVHKQM-LEELRFCANHWSEENSIGNIFLKFASDLVKAYPPYVNFFE 899
Query: 466 RSERLRETLVDT----HLFLQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
++ + + H FL+ CQ + + L L+KPVQR+ LLL D+L+++
Sbjct: 900 NTKEMLDQCDQNKPRFHAFLKICQTKPECGRQSLKELLIKPVQRLPSISLLLNDILKHTH 959
Query: 521 CGSMT-TGLQQALDCMLVVLKCVND 544
+ + L+++L + V+ +N+
Sbjct: 960 KSNPDHSALEKSLSSIKEVMTYINE 984
>UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersectin 1;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
intersectin 1 - Tribolium castaneum
Length = 1577
Score = 44.0 bits (99), Expect = 0.015
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 6/125 (4%)
Query: 428 FLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHL----FLQA 483
FL DL S+ + + K ++Y +C S L + L +T ++
Sbjct: 1142 FLSDLYDWTSSGSDILGPVISKHLQNMQVYEVFCGKQLDSAALLQKLTETSTAFRDLMRK 1201
Query: 484 CQLRLGHK-LPLAAYLLKPVQRITKYQLLLKDLL-RYSECGSMTTGLQQALDCMLVVLKC 541
CQ + K +PL+++L+KP+QRIT+Y LL+ ++ +E LQ+AL L
Sbjct: 1202 CQNNVATKGMPLSSFLIKPMQRITRYPLLISKIIENTAEDHPDYESLQEALRNAEKFLND 1261
Query: 542 VNDSM 546
+N+++
Sbjct: 1262 INENV 1266
>UniRef50_UPI00004992B4 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 696
Score = 44.0 bits (99), Expect = 0.015
Identities = 36/130 (27%), Positives = 67/130 (51%), Gaps = 11/130 (8%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFF 454
EN+ ++P + DV+F + ++ + + F LK+ + + + FVE FF
Sbjct: 67 ENKGIIPKN---KLDVIFLHFPDVQSMNSSFFEQLKEQKEKGKLYDCIGSIFVEFAH-FF 122
Query: 455 RLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHK--LPLAAYLLKPVQRITKYQ 509
++Y N L++ H+ +L+ +LR+ K L L +YL+ PVQR+ +Y
Sbjct: 123 KVYKLIVGNSEAVLAVLKDVCSSPHVSRYLEQQRLRINAKVQLDLRSYLITPVQRLPRYN 182
Query: 510 LLLKDLLRYS 519
LLL +LL+++
Sbjct: 183 LLLNELLKHT 192
>UniRef50_Q6FIT2 Cluster: Candida glabrata strain CBS138 chromosome
M complete sequence; n=2; Saccharomycetales|Rep: Candida
glabrata strain CBS138 chromosome M complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 840
Score = 44.0 bits (99), Expect = 0.015
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 10/162 (6%)
Query: 392 EIEKPENQHLLPPTLVGQADV--LFGNLHELFTFHQDVFLKDLE---RCISATELVALCF 446
E+ + + LL L+ ++ LF NL E F Q FL LE + + + F
Sbjct: 349 EVLERYREQLLESNLITSEELYMLFPNLGEAIDF-QRRFLASLEINALVEPSKQRIGALF 407
Query: 447 VEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRIT 506
+ + FF+LY + +I ++ + E L T + + +K+ L ++L KPVQR+
Sbjct: 408 MHSKY-FFKLYEPW--SIGQNAAI-EFLSSTLQKVSEEDFVIKNKMELQSFLYKPVQRLC 463
Query: 507 KYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+Y LLL++L + S L AL+ + + +N++ +
Sbjct: 464 RYPLLLRELAQQSVNDKSAKELDAALEISRSIARSINENQRR 505
>UniRef50_Q11100 Cluster: Putative protein tag-52; n=2;
Caenorhabditis|Rep: Putative protein tag-52 -
Caenorhabditis elegans
Length = 665
Score = 44.0 bits (99), Expect = 0.015
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 13/128 (10%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
+FG + + HQ + L+ L+ C E+ K F +LY+ Y + P S ++
Sbjct: 98 MFGEISAICKTHQ-ILLESLQ-CKPIAEVFT-----KFVPFLKLYTSYASHYPNSLKIFA 150
Query: 473 TLVDTHLFLQACQL-----RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTG 527
L+ + F +A R+ K L YL+ P+QRI +Y +L+++L+ YS T
Sbjct: 151 KLMSRNDFRKALTKIEEDPRVDGK-KLQTYLIMPIQRIPRYIMLIQNLMNYSTEKDDMTN 209
Query: 528 LQQALDCM 535
L +AL M
Sbjct: 210 LYKALSGM 217
>UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor 6;
n=19; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 6 - Gallus gallus (Chicken)
Length = 764
Score = 44.0 bits (99), Expect = 0.015
Identities = 54/265 (20%), Positives = 102/265 (38%), Gaps = 11/265 (4%)
Query: 413 LFGNLHELFTFHQDV--FLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSER- 469
L GN+ E+ F Q + L+D+ + + V CF+ F LY YC N P +
Sbjct: 277 LLGNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSV 336
Query: 470 LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE--CGSMTTG 527
L + + F+++ L L L KP R+ KY LL++L R+ E
Sbjct: 337 LTQHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDV 396
Query: 528 LQQALDCMLVVLKCV---NDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXX 584
L+ +V +C ++ I + + ++ G+ + +S+
Sbjct: 397 LKAITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSE 456
Query: 585 XXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQG 644
+ L+ +L + + S Y + L + E +G+ FE+
Sbjct: 457 EKEERYFLLFSNVLLMLSASPRMS--GFIYQGRLPLTGMTLTKLEDAEGNEHMFEI-AGN 513
Query: 645 RCEVHTITAPTVEVKRAWVERIKRV 669
E T++ T + W+E ++R+
Sbjct: 514 MMERITVSCSTSQDLHEWLEHLQRL 538
>UniRef50_UPI000049A257 Cluster: Rho guanine nucleotide exchange
factor; n=3; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 489
Score = 43.6 bits (98), Expect = 0.020
Identities = 48/190 (25%), Positives = 90/190 (47%), Gaps = 18/190 (9%)
Query: 363 IYKDYDRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFT 422
+ K++ +C+ + +LI+ ++ EKP LL P Q ++FG + ++
Sbjct: 123 VVKEFITTESTYCEQLGVVENLIHQPLIKQ-EKP----LLTPE---QMKLIFGGVSVIYG 174
Query: 423 FHQDVFLKDLERCISA-TELVALCFVEKRET-FFRLYSYYCQNIPRSERLRETLVDTHLF 480
+ L++L +S T+ + T R+YS YCQ P+ +L ++ H F
Sbjct: 175 VNT-ALLENLREKLSVYTQNSRFGRIVLTFTPLLRVYSDYCQIYPQINQLVSSMKVPHPF 233
Query: 481 LQACQLRLGHK------LPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT-TGLQQALD 533
+L++ L + L+ P+QR+ +Y+LLLKDLL++ + +++ALD
Sbjct: 234 GTFYKLQMKQAPEHLQGFDLLSLLITPIQRLPRYRLLLKDLLKHLRPSDVDYEDVKKALD 293
Query: 534 CMLVVLKCVN 543
+ V VN
Sbjct: 294 EIEKVTSFVN 303
>UniRef50_A7S9N2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1363
Score = 43.6 bits (98), Expect = 0.020
Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 6/102 (5%)
Query: 454 FRLYSYYCQNIPRSER-LRETLV---DTHLFLQACQL-RL-GHKLPLAAYLLKPVQRITK 507
F Y YC R + +E ++ D ++ C+ RL ++L L YL+KP+QR+TK
Sbjct: 512 FEPYITYCMEESRCLKYFKEKIIENEDFRTYITWCEEHRLCTNRLKLTDYLVKPMQRLTK 571
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
Y LLLK + + ++ M G+ + + + +L VN +M ++
Sbjct: 572 YPLLLKAIHKKTQDEEMKEGIWKMILTVESLLSKVNGAMREM 613
>UniRef50_Q4P2N2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1444
Score = 43.6 bits (98), Expect = 0.020
Identities = 38/147 (25%), Positives = 66/147 (44%), Gaps = 13/147 (8%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALC----FVEKRETFFRLYSYYCQNI 464
+A LFGN+ E+ ++ FL DLER S L + + F Y+ Y N
Sbjct: 273 EAQKLFGNIGEIAGANR-AFLNDLERLASQGHQALLAGLGDVLYNHMSCFSCYTEYFANF 331
Query: 465 PRSERLRETLVDTHLFLQACQLRLGHKLP------LAAYLLKPVQRITKYQLLLKDLLRY 518
+++ + TL F R + + L L++P+QRI +Y+LL+ +L++
Sbjct: 332 EKAKHIERTLAKHRAFCDFTD-RTKYSVTDIGNTGLRDLLMEPIQRIPRYKLLIDAILKH 390
Query: 519 SE-CGSMTTGLQQALDCMLVVLKCVND 544
E + L+QA+ + + C D
Sbjct: 391 VEPRDPLRNRLEQAISLVSRIASCEAD 417
>UniRef50_A6R7R1 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 1976
Score = 43.6 bits (98), Expect = 0.020
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 6/77 (7%)
Query: 446 FVEKRETFFRLYSYYCQNIPRSERLRETLV---DTHLFLQACQ---LRLGHKLPLAAYLL 499
FVE E ++YS Y +N + R E L+ + +++L+ C+ + L L + L+
Sbjct: 1317 FVEHIERMEKVYSEYLRNHDAANRTLEVLMRKSNVNIWLKECRDWAVDLTSAWNLDSLLV 1376
Query: 500 KPVQRITKYQLLLKDLL 516
KPVQRI KY LLL +LL
Sbjct: 1377 KPVQRIVKYPLLLTELL 1393
>UniRef50_UPI0000E4A769 Cluster: PREDICTED: similar to vav 2
oncogene, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to vav 2 oncogene,
partial - Strongylocentrotus purpuratus
Length = 318
Score = 43.2 bits (97), Expect = 0.026
Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISA-TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
D +F N+ EL H+ FL+DLE T +A F +K + F +Y +YC ++ ++
Sbjct: 189 DKIFLNIEELLRRHRG-FLRDLEDAFRRPTPTMAHAF-KKHKPDFLIYGFYCAHMLGAQN 246
Query: 470 LRETLVDTHLF---LQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
E + + ++ + + K L L P+QRI KY LLLK+L++ ++
Sbjct: 247 HIEKVSNNPQIRAKIEEFERKANDRKFRLRDLLSVPMQRILKYHLLLKELVKSTD 301
>UniRef50_UPI0000DA2C9A Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 6; n=1; Rattus norvegicus|Rep:
PREDICTED: similar to FYVE, RhoGEF and PH domain
containing 6 - Rattus norvegicus
Length = 1445
Score = 43.2 bits (97), Expect = 0.026
Identities = 37/117 (31%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVNDSMHQ-- 548
L L YLLKPVQRI +Y+LLL D L+ E Q AL ++ V ND+M Q
Sbjct: 983 LALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGD 1042
Query: 549 --IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKP 603
+ + LS E++ G + + E IFL+ A+L+ P
Sbjct: 1043 NFQKLMQIQYSLSGHHEIVQPGR-VFLKEGILMKLSRKVMQPRMIFLFNDALLYTTP 1098
>UniRef50_UPI000069E0AF Cluster: Proto-oncogene DBL (Proto-oncogene
MCF-2) [Contains: MCF2-transforming protein;
DBL-transforming protein].; n=1; Xenopus tropicalis|Rep:
Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains:
MCF2-transforming protein; DBL-transforming protein]. -
Xenopus tropicalis
Length = 602
Score = 43.2 bits (97), Expect = 0.026
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKD 431
GY+ E+E P H +P +L ++LFGN+ E++ FH K+
Sbjct: 549 GYRSEMENPAMMHFMPQSLRNMKNILFGNMPEIYEFHNKYMNKN 592
>UniRef50_Q4RBE6 Cluster: Chromosome undetermined SCAF21594, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF21594,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 51
Score = 43.2 bits (97), Expect = 0.026
Identities = 21/40 (52%), Positives = 26/40 (65%)
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
G T L++AL +L ++K VNDSMHQIAITG V Q
Sbjct: 8 GERTAELEEALATVLDIIKSVNDSMHQIAITGFEVSRPDQ 47
>UniRef50_Q17DC1 Cluster: Still life, putative; n=5;
Endopterygota|Rep: Still life, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 2068
Score = 43.2 bits (97), Expect = 0.026
Identities = 43/161 (26%), Positives = 75/161 (46%), Gaps = 22/161 (13%)
Query: 405 TLVGQADV--LFGNLHELFTFHQDVFLKDLERCISA----------TELVALCFVEKRE- 451
T + A++ LFGN+ E+ TF + FL +LE + ++ + F
Sbjct: 1330 TFLSNAEITALFGNIQEIVTFQRQ-FLSNLEEALDLEPDFHQLEHPSQFKNVLFAIGSAF 1388
Query: 452 ----TFFRLYSYYCQNIPRSERL---RETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQR 504
F+LYS +C + +++++ E FL A + H L ++L+KP+QR
Sbjct: 1389 LYYVNHFKLYSSFCASHSKAQKVLHPNEGNQALQEFLVARNPKQQHSSTLESFLIKPIQR 1448
Query: 505 ITKYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
I KY LLL+ L ++ + L +AL M V + +N+
Sbjct: 1449 ILKYPLLLQQLRNLTDPNAAEHLHLVEALKGMEKVAEHINE 1489
>UniRef50_Q9NVK9 Cluster: CDNA FLJ10665 fis, clone NT2RP2006200;
n=18; Theria|Rep: CDNA FLJ10665 fis, clone NT2RP2006200
- Homo sapiens (Human)
Length = 790
Score = 43.2 bits (97), Expect = 0.026
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>UniRef50_Q9NR81 Cluster: Rho guanine nucleotide exchange factor 3;
n=67; Fungi/Metazoa group|Rep: Rho guanine nucleotide
exchange factor 3 - Homo sapiens (Human)
Length = 526
Score = 43.2 bits (97), Expect = 0.026
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>UniRef50_UPI00015B40BC Cluster: PREDICTED: similar to GA20259-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA20259-PA - Nasonia vitripennis
Length = 856
Score = 42.7 bits (96), Expect = 0.035
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 13/149 (8%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVA--------LCFVEKRETFFRLYSYYCQNI 464
LF N+ E++ +++ + + + + A L E E F Y+ YC
Sbjct: 225 LFSNIPEIYAANREFWTEHIAAMLDAARSTRQPLDPGHLLQGFESFEKIFAPYTRYCSEQ 284
Query: 465 PRSERL-RETLVDTHLF---LQACQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ ++ R+ L D LF L C+ + ++L L L+KP+QRITKY LLLK + + +
Sbjct: 285 SKCQQYCRDRLNDNDLFTAYLVWCETQKDCNRLRLLDILVKPMQRITKYSLLLKAVHKNT 344
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
E L + + + VN +M +
Sbjct: 345 EHEEQRAELTIMIKSVDTFVASVNAAMRR 373
>UniRef50_UPI0000DB6C3F Cluster: PREDICTED: similar to CG7397-PA; n=1;
Apis mellifera|Rep: PREDICTED: similar to CG7397-PA -
Apis mellifera
Length = 1717
Score = 42.7 bits (96), Expect = 0.035
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-- 441
L+N Y + ++ EN L+ V D +F + + H +VFL++L + + EL
Sbjct: 881 LVNK-YLQPLKSSENAGLVDSATV---DEIFYQIPAILN-HHEVFLEELRKRLDTWELKQ 935
Query: 442 -VALCFVE--KRETFFRLYSYYCQNIPRSERLRETLVDTH----LFLQACQLRLGHKLPL 494
+ F++ + Y+ + N + + +T FL+ + KL L
Sbjct: 936 TIGDVFLDVFTKPVVLETYTLFLDNWKSARKAIKTTCQAKPAFARFLETMEREHKGKLGL 995
Query: 495 AAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQA 531
L+KPVQ+I +Y+LL++ LL++++ L QA
Sbjct: 996 DQLLIKPVQKIPRYELLIQRLLKHTDATHPDFELLQA 1032
>UniRef50_UPI00004983B6 Cluster: cell division control protein
CDC24; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell
division control protein CDC24 - Entamoeba histolytica
HM-1:IMSS
Length = 749
Score = 42.7 bits (96), Expect = 0.035
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVA--LCFVEKRETFFRLYSYYCQNIPRSER 469
++F N+ E++ F+ FL DL++ + + ++ E +Y+ Y N S
Sbjct: 260 IIFNNMEEIYQFNSK-FLNDLKKATEDMKPNKPWINVYKELEGALSVYTPYLVNYSESIE 318
Query: 470 LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
E ++ A G+ +++YL+ P+QR+ +Y LLL +L +++
Sbjct: 319 RVEQILCIECVRDALMKEKGNDKDMSSYLIMPIQRLPRYVLLLNELKKHT 368
>UniRef50_UPI0000ECD505 Cluster: Rho guanine nucleotide exchange
factor (GEF) 19; n=2; Gallus gallus|Rep: Rho guanine
nucleotide exchange factor (GEF) 19 - Gallus gallus
Length = 520
Score = 42.7 bits (96), Expect = 0.035
Identities = 37/131 (28%), Positives = 68/131 (51%), Gaps = 7/131 (5%)
Query: 453 FFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITK 507
F R+Y Y N E+ + L+ + Q RL +L L ++L+ P QRIT+
Sbjct: 185 FRRVYLPYVTNQTYQEQTFQRLLSGNAGFQQVLERLESDPVCQRLSLKSFLILPFQRITR 244
Query: 508 YQLLLKDLLRYSECGS-MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
+LLL+++L+ + GS QA D + ++K N+++ ++ T + LSQ+ E
Sbjct: 245 LKLLLQNILKRTRPGSEEEVQATQAYDALEKLIKDCNENVQRMRSTEELIYLSQKIEFEC 304
Query: 567 QGSFLVVSENK 577
+ F +VS+++
Sbjct: 305 K-IFPLVSQSR 314
>UniRef50_Q4RXA2 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 334
Score = 42.7 bits (96), Expect = 0.035
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 11/139 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC---FVEKRETFFRLYSYYCQNIPRSER 469
LF N+ + Q FL DLE + + ++ ++ F RLY Y N+ E
Sbjct: 51 LFSNILGVMAASQH-FLLDLEARLERSVIIPQVGDVVLQHCPAFRRLYMPYVTNMMYQEA 109
Query: 470 LRETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
L + L+ + + +L + L ++L+ P QRIT+ +L+L+++L+ +E GS
Sbjct: 110 LVDQLLQQNRAFSSLVRKLESEPVCQRQSLKSFLVLPFQRITRIKLILENILKLTEPGSD 169
Query: 525 TTG-LQQALDCM-LVVLKC 541
T G L+ A++ + +V+ C
Sbjct: 170 TIGDLEGAVEAIHEIVVSC 188
>UniRef50_Q17AI6 Cluster: Guanine nucleotide exchange factor; n=3;
Culicidae|Rep: Guanine nucleotide exchange factor -
Aedes aegypti (Yellowfever mosquito)
Length = 531
Score = 42.7 bits (96), Expect = 0.035
Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 10/125 (8%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRE 472
+FG L ++ Q++ LK L+ + + V F+ FF+LYS Y + S +
Sbjct: 115 IFGQLETIYNLSQEL-LKKLDDDL---DNVVRAFMNLGP-FFKLYSVYAFDYRNSLCTLQ 169
Query: 473 TLVDTH----LFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRY-SECGSMTTG 527
TL+ + F+ + R + + + L+ P+QRI +Y+LLL+ +L Y S C
Sbjct: 170 TLIQKNPAMKRFIANAESRPEVQTKVISLLITPIQRIPRYKLLLQQVLLYTSPCDGAYKQ 229
Query: 528 LQQAL 532
LQ+++
Sbjct: 230 LQESI 234
>UniRef50_Q5TEV1 Cluster: Rho guanine nucleotide exchange factor
(GEF) 19; n=3; Catarrhini|Rep: Rho guanine nucleotide
exchange factor (GEF) 19 - Homo sapiens (Human)
Length = 306
Score = 42.7 bits (96), Expect = 0.035
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 108 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 166
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 167 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 226
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 227 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 264
>UniRef50_Q8IW93 Cluster: Rho guanine nucleotide exchange factor 19;
n=20; Theria|Rep: Rho guanine nucleotide exchange factor
19 - Homo sapiens (Human)
Length = 802
Score = 42.7 bits (96), Expect = 0.035
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 420 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 478
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 479 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 538
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 539 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 576
>UniRef50_UPI0000E48DF2 Cluster: PREDICTED: similar to Bcr protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Bcr protein - Strongylocentrotus purpuratus
Length = 856
Score = 42.3 bits (95), Expect = 0.046
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 9/163 (5%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCIS--ATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
D +F + ELF H+ F+ +E + E + + + F ++ Y N R+
Sbjct: 119 DTMFFRIPELFNVHRQ-FVNHMEPKMKEWTPEQMQGDSFKLLASHFDIHEEYIANYKRAM 177
Query: 468 ERLRETLVDTHLFL----QACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-ECG 522
L+ + LF QA +L G L A L P+Q ITK ++L DLL+++ E
Sbjct: 178 STLQHLQSENELFRNIAQQALKLSSGEMYTLEAMLYSPLQGITKLTMILNDLLKHTPEHH 237
Query: 523 SMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
+ L Q L+ K V+++ +I T +L +QG L+
Sbjct: 238 EDHSILSQVLEKTRKFFKQVDEATREIHSTKQKRELLRQGYLV 280
>UniRef50_UPI000049A5B0 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 522
Score = 42.3 bits (95), Expect = 0.046
Identities = 22/57 (38%), Positives = 40/57 (70%), Gaps = 1/57 (1%)
Query: 491 KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVNDSM 546
KL L ++L+ PVQR+ +Y+LLL+DLL+ + G++ + L AL+ + V+ +N+S+
Sbjct: 137 KLDLNSFLIMPVQRVPRYRLLLQDLLKNTPDGTLGKSALATALEQIKVLGISINESI 193
>UniRef50_UPI000049944B Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 835
Score = 42.3 bits (95), Expect = 0.046
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 411 DVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFR---LYSYYCQNIPRS 467
D LF N +++ H +F K ER +S E + + FF +Y Y + + +
Sbjct: 565 DTLFSNFKDVYEIHTRLFKKISERWLSQKEEAFVSIADIFIDFFNWKEVYDAYARYLVEA 624
Query: 468 ERLRETLVDTHLFLQACQLRL--GHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + QL G L LA +L+ PVQR+ +Y LLL+ LL+ +
Sbjct: 625 DDGIQFDFSEKPKIIKDQLTTWAGQCLILANFLILPVQRLPRYVLLLESLLKATPPIEEY 684
Query: 526 TGLQQALD 533
L+QALD
Sbjct: 685 DYLKQALD 692
>UniRef50_Q4S5A8 Cluster: Chromosome 19 SCAF14731, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 19
SCAF14731, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1225
Score = 42.3 bits (95), Expect = 0.046
Identities = 41/140 (29%), Positives = 68/140 (48%), Gaps = 10/140 (7%)
Query: 417 LHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSERLRETL 474
L +L+ ++D+ L++LE ++ ++ L FV+K + ++YS Y + + L +
Sbjct: 771 LPQLYQLNKDL-LRELEERVAQSDHQTLSDIFVQKGP-YLKMYSTYIRQFDNNVALLDEQ 828
Query: 475 VDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGL 528
+ A + + + L L YLLKPVQRI +YQLLL D L+ E +
Sbjct: 829 CRKNTAFAAVVREFEMSPRCASLALKHYLLKPVQRIPQYQLLLTDYLKNLPEESADYKDT 888
Query: 529 QQALDCMLVVLKCVNDSMHQ 548
Q AL + V N+ M Q
Sbjct: 889 QAALSIVKEVANHANNIMKQ 908
>UniRef50_Q9VS45 Cluster: CG8606-PA, isoform A; n=4; Sophophora|Rep:
CG8606-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 647
Score = 42.3 bits (95), Expect = 0.046
Identities = 32/112 (28%), Positives = 61/112 (54%), Gaps = 9/112 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLR 471
+LFG + + + + FL++LE + E VA F+ K FF+LYS Y + + +
Sbjct: 113 LLFGQIEMIHNLNGE-FLRELE---ANMENVAHAFL-KMAPFFKLYSVYAFDYRGALFII 167
Query: 472 ETLVDTH----LFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ L+ + FL+ + R + L + ++ P+QR+ +Y+LLL+ +L Y+
Sbjct: 168 QDLISKNPVFRKFLEQTESRPEVQRKLNSLMIVPIQRVPRYKLLLEQVLLYT 219
>UniRef50_Q54PK2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1170
Score = 42.3 bits (95), Expect = 0.046
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 433 ERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQL--RLGH 490
E+ +S + +A FV + F + Y YC N ++ L + A L R
Sbjct: 796 EKPLSFIDHIASGFVSMAD-FLKSYFVYCSNQQKALSTFSALKGKNCTYLAYLLTRRECR 854
Query: 491 KLPLAAYLLKPVQRITKYQLLLKDLLR 517
LP ++L+KPVQR+ KY LL+++L++
Sbjct: 855 SLPFDSFLIKPVQRVCKYPLLIRELIK 881
>UniRef50_Q54B37 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=1; Dictyostelium discoideum AX4|Rep:
Pleckstrin homology (PH) domain-containing protein -
Dictyostelium discoideum AX4
Length = 1155
Score = 42.3 bits (95), Expect = 0.046
Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS----E 468
+F N+ +++ ++ ++ E IS T + F ++ ++YS YC +S
Sbjct: 742 IFSNIEQIWQINKQLY----ENLISNTLTIGQVFSNMSDSL-KVYSVYCNYHQKSLDSLN 796
Query: 469 RLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
+L +T + F Q + ++L+KPVQRI KY LLLK+LL+
Sbjct: 797 QLLKTPQNESFFDQLLSKPELRGMGPHSFLIKPVQRICKYPLLLKELLK 845
>UniRef50_A0CIG3 Cluster: Chromosome undetermined scaffold_19, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_19,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1132
Score = 42.3 bits (95), Expect = 0.046
Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
Query: 426 DVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFL 481
++F K E+ + LVA +++ +FF++YS Y N ++ +L++ FL
Sbjct: 206 EIFRKKQEQ-FTYYSLVADIQLQQHISFFKIYSTYLVNYQKAFSVQMKLKKENKPYKQFL 264
Query: 482 QACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
A + K + +L+ PVQRI KY LL KDLL+
Sbjct: 265 DAIDKQNQGKTLESYFLILPVQRIPKYVLLFKDLLK 300
>UniRef50_Q7S4Y3 Cluster: Putative uncharacterized protein
NCU06067.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU06067.1 - Neurospora crassa
Length = 970
Score = 42.3 bits (95), Expect = 0.046
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 6/118 (5%)
Query: 494 LAAYLLKPVQRITKYQLLLKDLLRYSE----CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
L +LLKP+QR+ KY LLLKDLL+ SE + G+ A ++ V+ ++ +
Sbjct: 333 LDGFLLKPMQRLVKYPLLLKDLLKKSEDEHTKEDLAAGIAAAERVLMKANSAVDKNILEE 392
Query: 550 AITGV--PVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPAT 605
A+ + VD + ++ GS L+ I+L+E +L CK T
Sbjct: 393 ALQDLIHRVDDWKSHKVDNFGSLLLHGVYTVITGKSEQEKDYEIYLFENILLCCKELT 450
>UniRef50_UPI0000DB6D3E Cluster: PREDICTED: similar to RhoGEF2
CG9635-PD, isoform D; n=1; Apis mellifera|Rep: PREDICTED:
similar to RhoGEF2 CG9635-PD, isoform D - Apis mellifera
Length = 1768
Score = 41.9 bits (94), Expect = 0.061
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 18/156 (11%)
Query: 409 QADVLFGNLHELFTFH----QDVFLKDLER-CISATE--LVALCFVEKRETFFRLYSYYC 461
Q +LF NL E+ T H Q + K E C+ L+ + E ETF R S YC
Sbjct: 1101 QIQLLFSNLDEMVTIHSRFNQAMKRKKKENPCVGDVGDLLLDMFDGENGETFERAASIYC 1160
Query: 462 --QNIP----RSERLRETLVDTHLFLQACQLR-LGHKLPLAAYLLKPVQRITKYQLLLKD 514
Q + R R ++ +++ FL + L +L L ++L + R+TKY LL ++
Sbjct: 1161 AKQQVALDALRDRRRKDPKLNS--FLNEIEANPLCRRLQLKDHILTGMLRLTKYPLLFEN 1218
Query: 515 LLRYSECGS--MTTGLQQALDCMLVVLKCVNDSMHQ 548
L +Y+ + + ++LD +L CVN ++ +
Sbjct: 1219 LAKYTPESNEKERAAVLRSLDRSKEILSCVNQAVRE 1254
>UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3 - Strongylocentrotus
purpuratus
Length = 399
Score = 41.9 bits (94), Expect = 0.061
Identities = 51/241 (21%), Positives = 106/241 (43%), Gaps = 17/241 (7%)
Query: 409 QADVLFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQN-IP 465
+ +++FG+L EL H+++ L+ ATE V ++ +Y YC N +
Sbjct: 102 ELNIIFGSLEELRMIHEELVCDLQKQRGNNGATEEVGKVLLKWLPLVTEVYVTYCTNQLA 161
Query: 466 RSERLRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR----- 517
L E D+ + FL+ C + KL L +L P R+ KY LL K++L+
Sbjct: 162 AKTLLDEKKQDSKVNDFLERCIESPFSRKLDLWNFLDVPRSRLVKYPLLFKNILKGTPSD 221
Query: 518 YSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAI-TGVPVDLSQQGELLMQGSFLVVSEN 576
+ + ++T ++ + + V + ++ + I T +D Q+ L+ L+
Sbjct: 222 HEDKINITLAIKMCKEIVSEVDRRTGETKCKHFIDTFEYLDDRQRNHLIAYQKNLLCG-- 279
Query: 577 KXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
H+FL+E ++ + T+N + K ++ + + + L + +G++R
Sbjct: 280 --GVLKSTKGTKLHVFLFEDILVVTRLITRN-NRKCYQVYRQPIPVRTMALEDIPEGEVR 336
Query: 637 K 637
+
Sbjct: 337 R 337
>UniRef50_UPI0000499FFA Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 631
Score = 41.9 bits (94), Expect = 0.061
Identities = 20/43 (46%), Positives = 31/43 (72%), Gaps = 2/43 (4%)
Query: 480 FLQACQLRLGHKL--PLAAYLLKPVQRITKYQLLLKDLLRYSE 520
FL+ C++++ K PL + L+ PVQRI +Y LLLKDLL+ ++
Sbjct: 150 FLEQCRIKIPSKSQQPLRSILIMPVQRIPRYVLLLKDLLKNTD 192
>UniRef50_Q7ZZ90 Cluster: Novel protein similar to human MCF.2 cell
line derived transforming sequence; n=7; Danio
rerio|Rep: Novel protein similar to human MCF.2 cell
line derived transforming sequence - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 600
Score = 41.9 bits (94), Expect = 0.061
Identities = 17/37 (45%), Positives = 25/37 (67%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFH 424
GY+ E++ P LLP +L + DVLFGNL +++ FH
Sbjct: 551 GYRAEMDNPSLAPLLPTSLRNKRDVLFGNLPDIYNFH 587
>UniRef50_Q4RFR9 Cluster: Chromosome 16 SCAF15113, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 16
SCAF15113, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1512
Score = 41.9 bits (94), Expect = 0.061
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 454 FRLYSYYCQN---IPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F++YS +C + +P+ ++ + FL + H L +YL+KP+QR+ KY L
Sbjct: 1123 FKIYSAFCASHTKVPKVLVKAKSDPNFKAFLDERNPKQQHSSTLESYLIKPIQRVLKYPL 1182
Query: 511 LLKDL 515
LLK+L
Sbjct: 1183 LLKEL 1187
>UniRef50_Q86B45 Cluster: CG8557-PB, isoform B; n=2; Drosophila
melanogaster|Rep: CG8557-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 1740
Score = 41.9 bits (94), Expect = 0.061
Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 22/184 (11%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCI- 436
++ L+N YK+ +E+ L P + LF L ++ H+ +F L C+
Sbjct: 473 VATLQRLVND-YKKPLEECSPPVLNPVKIA----TLFHCLPDILHSHK-LFRISLAECVR 526
Query: 437 --SATELVALCFVEK--RETFFRLYSYYCQNIPRS-------ERLRETLVDTHLFLQACQ 485
E + CFV + +YS + N + E+ + L D F + Q
Sbjct: 527 NWDRDEKIGDCFVSAFGKPQLLEIYSGFINNFSAAMELAKMEEKRKSALAD---FFKVKQ 583
Query: 486 LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVND 544
+ +L ++KPVQR ++ L L+DLL+Y+ G LQ AL + ++ + +N+
Sbjct: 584 ISAHDRLSFFGLMVKPVQRFPQFILFLQDLLKYTPQGHHDRMSLQLALSQLELLAELLNE 643
Query: 545 SMHQ 548
S +
Sbjct: 644 SKRE 647
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 41.9 bits (94), Expect = 0.061
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 417 LHELFTFHQDVFLKDLERCISATEL-VALCFVEKRETFFRLYSYYCQNIPRSERLRETLV 475
+HEL H K + C + ++ F++ R+ F + Y YC +P ++ + L
Sbjct: 314 VHELHKMHSKFVFKLEDACNRMDGVNISKLFLDCRDDFLK-YGNYCARMPDAQVHIDELS 372
Query: 476 --DTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLL 512
D L+ CQ R K L + L+ P QR+ KY LLL
Sbjct: 373 RRDAKFKDILEECQKRANSKFTLRSLLVVPFQRVLKYPLLL 413
>UniRef50_A0D4V7 Cluster: Chromosome undetermined scaffold_38, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_38,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 572
Score = 41.9 bits (94), Expect = 0.061
Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 446 FVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRI 505
F+ + +F+ Y Y R R D HL + Q L L ++L+KPVQR+
Sbjct: 178 FIPYFKIYFKYYYEYKDYQIRDLRQAYPAFDNHLNILE-QGNLFRGCDLNSFLVKPVQRL 236
Query: 506 TKYQLLLKDLLRYS 519
KY LLLKDL++++
Sbjct: 237 PKYALLLKDLVKHT 250
>UniRef50_Q6CBW7 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 769
Score = 41.9 bits (94), Expect = 0.061
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 494 LAAYLLKPVQRITKYQLLLKDLLRYSECG-SMTTGLQQALDCMLVVLKCVNDSMHQIAIT 552
L A+L+KP+QRI KY LLL++L++ S + L L+ + V VN++ ++
Sbjct: 390 LQAFLIKPIQRICKYPLLLRELVKVSSSDHPYASELLDGLEAIKRVTNSVNETQRRVENV 449
Query: 553 GVPVDLSQQ 561
+ DL ++
Sbjct: 450 AIIQDLCER 458
>UniRef50_Q6GLN1 Cluster: LOC443708 protein; n=2; Xenopus|Rep:
LOC443708 protein - Xenopus laevis (African clawed frog)
Length = 669
Score = 41.5 bits (93), Expect = 0.080
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 11/142 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLER--CISATEL--VALCFVEKRETFFRLYSYYCQNIPRSE 468
LF N+ E+ + +FL DL+ C L + F+ YS YC RS
Sbjct: 57 LFCNVDEILQVAK-LFLADLKNMECNGQYHLKQIGELFLNFSTDMQNTYSTYCWEYQRSL 115
Query: 469 RLRETLVDTHLFLQACQL-RLGHKLP----LAAYLLKPVQRITKYQLLLKDLLR-YSECG 522
L E ++ ++L +L G P ++ L+ PVQRITKY LLL +L+ G
Sbjct: 116 SLLEQYKESEIYLHIKELLHSGLSKPKCSDISFILVMPVQRITKYPLLLLSILKNCPPNG 175
Query: 523 SMTTGLQQALDCMLVVLKCVND 544
+Q A M V + +N+
Sbjct: 176 EEHVAIQNAYSAMQEVNQNINE 197
>UniRef50_A3QJZ2 Cluster: Novel protein similar to vertebrate Rho
guanine nucleotide exchange factor (GEF) 15; n=13;
Euteleostomi|Rep: Novel protein similar to vertebrate
Rho guanine nucleotide exchange factor (GEF) 15 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 515
Score = 41.5 bits (93), Expect = 0.080
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 11/146 (7%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCISATEL---VALCFVEKRETFFRLYSYYCQNIPRSE 468
VLF NL +++ + F++DL + + + + V+ E E F +Y Y +N E
Sbjct: 132 VLFSNLLQVYEVSER-FIRDLLKRVDESVVISDVSDIIYEHSENHFSVYIDYVRNQQYQE 190
Query: 469 R----LRETLVDTHLFLQACQLR-LGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
+ L E+ D + ++ +L L +LP +++L P QRIT+ ++L++ + + + G
Sbjct: 191 KTYSKLMESNTDFAVVMRRLELSPLCKRLPFTSFMLLPFQRITRIKILIQSIQKRTAKG- 249
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQI 549
T + A + V K + + Q+
Sbjct: 250 -TKEEETASKALTSVSKLITQANQQV 274
>UniRef50_A0CSX7 Cluster: Chromosome undetermined scaffold_26, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_26,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1085
Score = 41.5 bits (93), Expect = 0.080
Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 416 NLHELFTFHQDVFLKDLERC--ISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
N+HE+ F+ + FL +L++ + + + + F Y YC+ ++ ++
Sbjct: 300 NIHEILKFNTE-FLSELQKKNNLKDPNAIVMDSIVPLLNGFIFYYEYCKAYEQARKITTQ 358
Query: 474 LVDTHLFLQACQ----LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
F Q + L L L Y +KPVQR+ KY LL KDLL+++
Sbjct: 359 YEAIPAFQQCIKDIEVQNLLKGLSLNDYTIKPVQRLPKYVLLFKDLLKHT 408
>UniRef50_UPI0000F208BC Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1151
Score = 41.1 bits (92), Expect = 0.11
Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 16/128 (12%)
Query: 557 DLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHF 616
DL+ GEL+++GSF + +FL+++ +L K + H Y +
Sbjct: 60 DLTTYGELVLEGSFRIHRAKNERT----------LFLFDRMLLITK--RRGEH----YVY 103
Query: 617 KHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKE 676
K + S + L ES K L + + HT+ A T+E K+ W IKR++++ +
Sbjct: 104 KTHISCSTLMLIESAKDSLCFSVTHYKHPKQPHTVQARTLEEKKLWAHHIKRLIIENHQA 163
Query: 677 LKGERVRQ 684
+ ++ ++
Sbjct: 164 VIPQKAKE 171
>UniRef50_UPI0000E46F96 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 991
Score = 41.1 bits (92), Expect = 0.11
Identities = 41/177 (23%), Positives = 78/177 (44%), Gaps = 17/177 (9%)
Query: 380 QCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT 439
Q + Y + ++ P+N L + +V+F + E+ HQ FL LE +
Sbjct: 72 QSLDFLVKSYLQPLKSPDNSSLCDQASL---EVMFYKIPEILLNHQQ-FLDQLEDRMKRW 127
Query: 440 -------ELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGH-- 490
++++ F + + YS + N +++ L F + + R
Sbjct: 128 HSEQKIGDIISQSFAQ--QPILDTYSEFTNNFNKAKNLISKATTKPAFAKFLEERAKENK 185
Query: 491 -KLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGSMTTGLQQALDCMLVVLKCVNDS 545
KL L+ +++P+QRI +Y+LLLK+L+ ++ LQ AL + + K +N S
Sbjct: 186 EKLSLSDLIIQPIQRIPRYELLLKELIDNTADDHPDQELLQNALSTVNTLAKAINAS 242
>UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3799-PA, isoform A - Tribolium castaneum
Length = 968
Score = 41.1 bits (92), Expect = 0.11
Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELV-ALC-FVEKR-ETFFRLYSYYCQN-I 464
+ ++LFG + ++ + + + DLE+C L+ +C V+K E F +Y YC+N I
Sbjct: 574 ELEMLFGKVADVKNCSEKL-ISDLEKCWQENILLHGVCDIVQKHAEENFHVYVPYCENQI 632
Query: 465 PRSERLRETLVDTHLFLQACQLRLG---HKLPLAAYLLKPVQRITKYQLLLKDLLR 517
+ LR + Q QL L L ++L+ P+QRIT++ LL+ +L+
Sbjct: 633 LLDDTLRRIKERPNFLEQLKQLESSSTCQSLTLYSFLMLPMQRITRWPLLVDAVLK 688
>UniRef50_UPI0000D5630B Cluster: PREDICTED: similar to CG7323-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG7323-PA
- Tribolium castaneum
Length = 1625
Score = 41.1 bits (92), Expect = 0.11
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 367 YDRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQD 426
Y R L+ D C + S +K IE + T + A+V+F + LF +D
Sbjct: 985 YIRTLKVVTDLFLACLRDLQS-HKLLIEIDREKLFSNITEILDANVMFWR-NTLFPLIRD 1042
Query: 427 VFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLF---LQA 483
+ CI E +A F + ETF Y Y C R + +D+ +F L
Sbjct: 1043 MRQHKRTTCI---ENMAEGFSKIHETFQPYYKY-CAEQSRCQHYCRENMDSEVFTAYLTW 1098
Query: 484 CQLRLG-HKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
C+ + ++L L L++P+QR+TKY LLLK +L+ ++
Sbjct: 1099 CESQKECNRLRLMDILVQPMQRLTKYGLLLKAILKNTD 1136
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.132 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 779,845,462
Number of Sequences: 1657284
Number of extensions: 30619793
Number of successful extensions: 80236
Number of sequences better than 10.0: 400
Number of HSP's better than 10.0 without gapping: 219
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 79471
Number of HSP's gapped (non-prelim): 588
length of query: 749
length of database: 575,637,011
effective HSP length: 106
effective length of query: 643
effective length of database: 399,964,907
effective search space: 257177435201
effective search space used: 257177435201
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 76 (34.7 bits)
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