Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002693-TA|BGIBMGA002693-PA|IPR006162|Phosphopantetheine
attachment site, IPR001849|Pleckstrin-like,
IPR001331|Guanine-nucleotide dissociation stimulator, CDC24,
IPR000219|DH
(749 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC020208-1|AAH20208.1| 984|Homo sapiens MCF.2 cell line derived... 267 8e-71
BC011853-1|AAH11853.1| 984|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL596093-7|CAI39525.1| 984|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL596093-6|CAI94928.1| 1067|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL596093-4|CAI39524.2| 1096|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL596093-3|CAI39523.1| 1137|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL356740-10|CAH70245.1| 984|Homo sapiens MCF.2 cell line derive... 267 8e-71
AL356740-8|CAI94923.1| 1067|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL356740-6|CAH70244.2| 1096|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL356740-4|CAH70243.1| 1137|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL162454-4|CAI39871.1| 984|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL162454-3|CAI95103.1| 1067|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL162454-2|CAI39870.2| 1096|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL162454-1|CAI39869.1| 1137|Homo sapiens MCF.2 cell line derived... 267 8e-71
AL137002-20|CAI41392.1| 984|Homo sapiens MCF.2 cell line derive... 267 8e-71
AL137002-18|CAI95400.1| 1067|Homo sapiens MCF.2 cell line derive... 267 8e-71
AL137002-17|CAI41390.2| 1096|Homo sapiens MCF.2 cell line derive... 267 8e-71
AL137002-11|CAI41383.1| 1137|Homo sapiens MCF.2 cell line derive... 267 8e-71
AB116075-1|BAD08352.1| 904|Homo sapiens Ost-I protein. 267 8e-71
AB116074-1|BAD08351.1| 1067|Homo sapiens Ost-II protein. 267 8e-71
AB002360-1|BAA20817.1| 1108|Homo sapiens KIAA0362 protein. 267 8e-71
X12556-1|CAA31069.1| 925|Homo sapiens protein ( Human mRNA for ... 261 6e-69
J03639-1|AAA52172.1| 478|Homo sapiens MCF2 protein. 261 6e-69
AL161777-3|CAI39715.1| 1070|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL117234-1|CAB55301.1| 985|Homo sapiens hypothetical protein pr... 261 6e-69
AL033403-7|CAA21955.1| 925|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL033403-6|CAI42107.1| 941|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL033403-5|CAI42108.1| 860|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL033403-4|CAI42106.1| 528|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL033403-3|CAI42105.1| 428|Homo sapiens MCF.2 cell line derived... 261 6e-69
AL033403-2|CAI42104.1| 1070|Homo sapiens MCF.2 cell line derived... 261 6e-69
AB209679-1|BAD92916.1| 435|Homo sapiens MCF.2 cell line derived... 261 6e-69
AB085902-1|BAC41201.1| 941|Homo sapiens DBL proto-oncogene spli... 261 6e-69
AB085901-1|BAC41200.1| 860|Homo sapiens DBL proto-oncogene spli... 261 6e-69
X13230-1|CAA31617.1| 567|Homo sapiens protein ( Human mRNA for ... 260 2e-68
U94190-1|AAC15791.1| 1663|Homo sapiens Duo protein. 171 6e-42
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 167 2e-40
BC035585-1|AAH35585.1| 1627|Homo sapiens Similar to triple funct... 167 2e-40
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 167 2e-40
AB209754-1|BAD92991.1| 2202|Homo sapiens triple functional domai... 167 2e-40
AK125979-1|BAC86373.1| 738|Homo sapiens (Hapip). protein. 164 1e-39
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 164 1e-39
AK125163-1|BAC86068.1| 320|Homo sapiens protein ( Homo sapiens ... 156 3e-37
AB067496-1|BAB67802.2| 1287|Homo sapiens KIAA1909 protein protein. 154 1e-36
BC012860-1|AAH12860.1| 474|Homo sapiens RAC/CDC42 exchange fact... 150 2e-35
AY172737-1|AAO19651.1| 1031|Homo sapiens Rho family guanine-nucl... 147 1e-34
AB020668-1|BAA74884.1| 982|Homo sapiens KIAA0861 protein protein. 147 1e-34
BC047559-1|AAH47559.1| 580|Homo sapiens RAC/CDC42 exchange fact... 146 3e-34
AF487514-1|AAO49463.2| 580|Homo sapiens RAC/CDC42/Rho exchange ... 146 3e-34
BC054486-1|AAH54486.1| 1110|Homo sapiens PLEKHG4 protein protein. 144 1e-33
BC082974-1|AAH82974.1| 1151|Homo sapiens PLEKHG4 protein protein. 142 5e-33
BC063501-1|AAH63501.1| 1191|Homo sapiens PLEKHG4 protein protein. 142 5e-33
AK024475-1|BAB15765.1| 1194|Homo sapiens FLJ00068 protein protein. 142 5e-33
AB197663-1|BAE07054.1| 1191|Homo sapiens puratrophin-1 protein. 142 5e-33
AL137002-4|CAM24069.1| 312|Homo sapiens MCF.2 cell line derived... 138 9e-32
AL137002-5|CAM24070.1| 316|Homo sapiens MCF.2 cell line derived... 130 2e-29
AB115332-1|BAC79392.1| 255|Homo sapiens transforming gene produ... 125 7e-28
AL137629-1|CAB70850.1| 381|Homo sapiens hypothetical protein pr... 123 3e-27
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 113 3e-24
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 113 3e-24
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 113 3e-24
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 109 4e-23
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 109 4e-23
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 109 4e-23
AK131379-1|BAD18530.1| 851|Homo sapiens protein ( Homo sapiens ... 109 4e-23
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 109 4e-23
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 109 4e-23
BC129953-1|AAI29954.1| 1219|Homo sapiens PLEKHG3 protein protein. 108 8e-23
AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology dom... 106 2e-22
AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology dom... 106 2e-22
AK057416-1|BAB71477.1| 306|Homo sapiens protein ( Homo sapiens ... 103 2e-21
BC107066-1|AAI07067.1| 296|Homo sapiens BRSK2 protein protein. 93 3e-18
BC075858-1|AAH75858.1| 1253|Homo sapiens PLEKHG2 protein protein. 89 7e-17
AK024429-1|BAB15719.1| 1430|Homo sapiens FLJ00018 protein protein. 89 7e-17
AL137291-1|CAB70682.1| 658|Homo sapiens hypothetical protein pr... 88 9e-17
AK074057-1|BAB84883.1| 1546|Homo sapiens FLJ00128 protein protein. 88 9e-17
AK024463-1|BAB15753.1| 1310|Homo sapiens FLJ00056 protein protein. 88 9e-17
BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein. 79 8e-14
AY508997-1|AAS82572.1| 979|Homo sapiens P-Rex2B protein. 75 7e-13
AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein. 75 7e-13
AL137002-6|CAM24071.1| 335|Homo sapiens MCF.2 cell line derived... 75 7e-13
AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein. 75 7e-13
AY570973-1|AAS59407.1| 205|Homo sapiens PtdIns(3,4,5)-dependent... 73 3e-12
BC000084-1|AAH00084.3| 326|Homo sapiens FLJ10357 protein protein. 71 2e-11
AK001219-1|BAA91563.1| 278|Homo sapiens protein ( Homo sapiens ... 71 2e-11
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 70 3e-11
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 70 3e-11
AF249745-1|AAF79955.1| 720|Homo sapiens RhoGEF protein. 66 4e-10
AC009477-1|AAX93134.1| 547|Homo sapiens unknown protein. 66 4e-10
AB042199-1|BAB11941.1| 619|Homo sapiens APC-stimulated guanine ... 66 4e-10
AB029035-1|BAA83064.1| 694|Homo sapiens KIAA1112 protein protein. 66 4e-10
BC109291-1|AAI09292.1| 652|Homo sapiens spermatogenesis associa... 66 6e-10
BC109290-1|AAI09291.1| 652|Homo sapiens spermatogenesis associa... 66 6e-10
AL445192-1|CAI39886.1| 1659|Homo sapiens RP11-269H4.1 protein. 66 6e-10
AL359736-2|CAH72290.2| 574|Homo sapiens spermatogenesis associa... 66 6e-10
AL359736-1|CAH72289.1| 652|Homo sapiens spermatogenesis associa... 66 6e-10
AL133342-1|CAI23274.1| 1659|Homo sapiens RP11-269H4.1 protein. 66 6e-10
AL035106-1|CAI43186.1| 1659|Homo sapiens RP11-269H4.1 protein. 66 6e-10
AK160371-1|BAD18714.1| 527|Homo sapiens FLJ00298 protein protein. 66 6e-10
AK055770-1|BAB71009.1| 652|Homo sapiens factor. protein. 66 6e-10
AJ320261-1|CAC86401.1| 1659|Homo sapiens P-Rex1 protein protein. 66 6e-10
AB037836-1|BAA92653.2| 1621|Homo sapiens KIAA1415 protein protein. 66 6e-10
AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein. 64 1e-09
AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein. 64 1e-09
AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein. 64 1e-09
AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein. 64 1e-09
AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein. 64 1e-09
AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein. 64 1e-09
AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein. 64 1e-09
AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isof... 64 2e-09
BC029074-1|AAH29074.2| 271|Homo sapiens MCF2L2 protein protein. 63 3e-09
AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein. 63 4e-09
AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marke... 62 9e-09
AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein. 62 9e-09
Z85987-1|CAI42222.1| 961|Homo sapiens FYVE, RhoGEF and PH domai... 61 2e-08
U11690-1|AAA57004.1| 961|Homo sapiens FGD1 protein. 61 2e-08
BC064632-1|AAH64632.1| 711|Homo sapiens MCF2L2 protein protein. 61 2e-08
BC034530-1|AAH34530.1| 961|Homo sapiens FYVE, RhoGEF and PH dom... 61 2e-08
BC117406-1|AAI17407.1| 516|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL451106-3|CAI39552.1| 478|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL451106-1|CAI39550.1| 516|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL391277-3|CAI40403.1| 478|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL391277-2|CAI40402.1| 495|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL391277-1|CAI40401.1| 516|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL355142-3|CAI41197.1| 478|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL355142-2|CAI41196.1| 495|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AL355142-1|CAI41195.1| 516|Homo sapiens Cdc42 guanine nucleotid... 60 2e-08
AB007884-1|BAA24854.2| 567|Homo sapiens KIAA0424 protein. 60 2e-08
AL160264-1|CAI20471.1| 697|Homo sapiens FYVE, RhoGEF and PH dom... 60 4e-08
BC053655-1|AAH53655.1| 655|Homo sapiens FYVE, RhoGEF and PH dom... 58 1e-07
BC023645-1|AAH23645.1| 655|Homo sapiens FYVE, RhoGEF and PH dom... 58 1e-07
BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein. 58 2e-07
BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein. 58 2e-07
AL357934-1|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein. 58 2e-07
S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein. 56 5e-07
AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein. 56 5e-07
AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein. 56 5e-07
AL357934-2|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein. 56 5e-07
DQ424905-1|ABD83670.1| 630|Homo sapiens rho guanine nucleotide ... 56 6e-07
AK026111-1|BAB15364.1| 384|Homo sapiens protein ( Homo sapiens ... 55 8e-07
BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein pr... 54 1e-06
X83931-1|CAA58783.1| 539|Homo sapiens VAV protein. 53 4e-06
BC117196-1|AAI17197.1| 1591|Homo sapiens T-cell lymphoma invasio... 52 6e-06
BC117192-1|AAI17193.1| 1591|Homo sapiens T-cell lymphoma invasio... 52 6e-06
U16296-1|AAA98443.1| 1591|Homo sapiens TIAM1 protein protein. 52 7e-06
BC032429-1|AAH32429.1| 725|Homo sapiens FGD3 protein protein. 50 2e-05
AL596202-1|CAI14404.1| 1046|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AL355343-1|CAH73978.1| 1046|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AL139101-3|CAI20508.1| 1046|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AK000004-1|BAA92229.1| 698|Homo sapiens FLJ00004 protein protein. 50 2e-05
AF120324-1|AAF05901.1| 626|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AF120323-1|AAF05900.1| 1077|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AB209674-1|BAD92911.1| 1947|Homo sapiens T-cell lymphoma invasio... 50 2e-05
AB095936-1|BAC23112.2| 1715|Homo sapiens KIAA2016 protein protein. 50 2e-05
BC111054-1|AAI11055.1| 725|Homo sapiens FGD3 protein protein. 50 3e-05
AY211386-1|AAP20645.1| 634|Homo sapiens FGD3 protein. 50 3e-05
AL451065-1|CAI95107.1| 725|Homo sapiens FYVE, RhoGEF and PH dom... 50 3e-05
AL389924-2|CAI41118.1| 725|Homo sapiens FYVE, RhoGEF and PH dom... 50 3e-05
AK125459-1|BAC86170.1| 1268|Homo sapiens protein ( Homo sapiens ... 50 3e-05
BC066979-1|AAH66979.1| 626|Homo sapiens T-cell lymphoma invasio... 49 5e-05
BC036749-1|AAH36749.1| 841|Homo sapiens Rho guanine nucleotide ... 49 5e-05
AY367054-1|AAQ72372.1| 280|Homo sapiens actin-filament binding ... 49 5e-05
AB020722-1|BAA74938.2| 846|Homo sapiens KIAA0915 protein protein. 49 5e-05
D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein. 49 7e-05
BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein. 49 7e-05
BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide ... 49 7e-05
BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein. 49 7e-05
AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein pr... 49 7e-05
AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide ... 49 7e-05
AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant... 49 7e-05
AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant... 49 7e-05
BC045552-1|AAH45552.1| 471|Homo sapiens FGD4 protein protein. 48 2e-04
AK057294-1|BAB71413.1| 766|Homo sapiens protein ( Homo sapiens ... 48 2e-04
BX538322-1|CAD98096.1| 1210|Homo sapiens hypothetical protein pr... 46 6e-04
BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein. 46 6e-04
BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein. 46 6e-04
BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine nucleo... 46 6e-04
AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AJ238899-1|CAC00686.1| 425|Homo sapiens guanine nucleotide exch... 46 6e-04
AC016692-1|AAX93288.1| 582|Homo sapiens unknown protein. 46 6e-04
AB199796-1|BAF43710.1| 675|Homo sapiens hypothetical protein pr... 45 0.001
AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein. 45 0.001
BC109095-1|AAI09096.1| 790|Homo sapiens pleckstrin homology dom... 43 0.003
BC105961-1|AAI05962.1| 790|Homo sapiens pleckstrin homology dom... 43 0.003
BC104751-1|AAI04752.1| 790|Homo sapiens pleckstrin homology dom... 43 0.003
BC104723-1|AAI04724.2| 526|Homo sapiens Rho guanine nucleotide ... 43 0.003
BC098272-1|AAH98272.2| 526|Homo sapiens Rho guanine nucleotide ... 43 0.003
BC098122-1|AAH98122.2| 526|Homo sapiens Rho guanine nucleotide ... 43 0.003
BC068513-1|AAH68513.1| 576|Homo sapiens ARHGEF3 protein protein. 43 0.003
BC054345-1|AAH54345.2| 526|Homo sapiens Rho guanine nucleotide ... 43 0.003
AK095373-1|BAC04539.1| 758|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK024340-1|BAB14891.1| 412|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK023741-1|BAB14663.1| 522|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK001527-1|BAA91741.1| 790|Homo sapiens protein ( Homo sapiens ... 43 0.003
AF433662-1|AAP97313.1| 558|Homo sapiens RhoGEF protein protein. 43 0.003
AF249744-1|AAF79954.1| 526|Homo sapiens RhoGEF protein. 43 0.003
AB209661-1|BAD92898.1| 537|Homo sapiens Rho guanine nucleotide ... 43 0.003
D89016-1|BAA13745.1| 421|Homo sapiens Neuroblastoma protein. 43 0.005
BT007270-1|AAP35934.1| 421|Homo sapiens Rho guanine exchange fa... 43 0.005
BC053616-1|AAH53616.1| 1483|Homo sapiens PREX1 protein protein. 43 0.005
BC040640-1|AAH40640.1| 802|Homo sapiens Rho guanine nucleotide ... 43 0.005
BC012982-1|AAH12982.1| 706|Homo sapiens ARHGEF19 protein protein. 43 0.005
BC002681-1|AAH02681.1| 421|Homo sapiens Rho guanine exchange fa... 43 0.005
AL109627-10|CAI22568.1| 306|Homo sapiens Rho guanine nucleotide... 43 0.005
AL109627-9|CAI22566.1| 802|Homo sapiens Rho guanine nucleotide ... 43 0.005
BC051838-1|AAH51838.1| 421|Homo sapiens ARHGEF16 protein protein. 41 0.014
AL512413-2|CAH70833.1| 421|Homo sapiens Rho guanine exchange fa... 41 0.014
AL512413-1|CAH70832.1| 709|Homo sapiens Rho guanine exchange fa... 41 0.014
AK002045-1|BAA92052.1| 432|Homo sapiens protein ( Homo sapiens ... 41 0.014
BC013319-1|AAH13319.1| 376|Homo sapiens FGD6 protein protein. 41 0.018
D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein. 40 0.024
BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein. 40 0.024
BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 40 0.024
AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein. 40 0.024
AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 40 0.024
AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein. 40 0.024
AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein. 40 0.024
AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein. 40 0.024
AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine nucle... 40 0.024
AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 40 0.024
AB023227-1|BAA76854.1| 1315|Homo sapiens KIAA1010 protein protein. 40 0.024
U02081-1|AAB08847.1| 460|Homo sapiens guanine nucleotide regula... 40 0.032
BC053553-1|AAH53553.1| 596|Homo sapiens neuroepithelial cell tr... 40 0.032
BC041628-1|AAH41628.1| 823|Homo sapiens DNMBP protein protein. 40 0.032
BC010285-1|AAH10285.1| 542|Homo sapiens neuroepithelial cell tr... 40 0.032
AL732437-5|CAI11033.1| 596|Homo sapiens neuroepithelial cell tr... 40 0.032
AL732437-3|CAI11031.1| 542|Homo sapiens neuroepithelial cell tr... 40 0.032
AJ010046-1|CAA08974.1| 548|Homo sapiens guanine nucleotide-exch... 40 0.032
AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein. 40 0.043
AK000302-1|BAA91068.1| 436|Homo sapiens protein ( Homo sapiens ... 39 0.056
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 39 0.056
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 39 0.056
AC008073-6|AAY14668.1| 367|Homo sapiens unknown protein. 39 0.056
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 39 0.056
AL627434-1|CAI13196.1| 224|Homo sapiens novel protein protein. 39 0.074
AL392107-1|CAI11008.1| 224|Homo sapiens novel protein protein. 39 0.074
BC042606-1|AAH42606.1| 1043|Homo sapiens PLEKHG5 protein protein. 38 0.098
BC015231-1|AAH15231.1| 930|Homo sapiens PLEKHG5 protein protein. 38 0.098
AL591866-2|CAI16068.1| 852|Homo sapiens pleckstrin homology dom... 38 0.098
AL591866-1|CAI16069.1| 1083|Homo sapiens pleckstrin homology dom... 38 0.098
AL158217-13|CAI22165.1| 1062|Homo sapiens pleckstrin homology do... 38 0.098
AL158217-12|CAI22164.1| 1043|Homo sapiens pleckstrin homology do... 38 0.098
AL158217-10|CAI22162.1| 930|Homo sapiens pleckstrin homology do... 38 0.098
AL158217-9|CAI22161.1| 1006|Homo sapiens pleckstrin homology dom... 38 0.098
AL158217-8|CAI22160.1| 852|Homo sapiens pleckstrin homology dom... 38 0.098
AL158217-7|CAI22159.1| 1083|Homo sapiens pleckstrin homology dom... 38 0.098
AK131074-1|BAC85124.1| 922|Homo sapiens FLJ00260 protein protein. 38 0.098
AK097217-1|BAC04977.1| 304|Homo sapiens factor. protein. 38 0.098
AB097001-1|BAC77354.1| 910|Homo sapiens putative NFkB activatin... 38 0.098
AB018263-1|BAA34440.2| 1091|Homo sapiens KIAA0720 protein protein. 38 0.098
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 38 0.17
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 38 0.17
BC057394-1|AAH57394.1| 1562|Homo sapiens Rho guanine nucleotide ... 38 0.17
AL356104-3|CAH72940.1| 1522|Homo sapiens Rho guanine nucleotide ... 38 0.17
AL356104-2|CAH72939.1| 1562|Homo sapiens Rho guanine nucleotide ... 38 0.17
AL157713-2|CAH70127.1| 1522|Homo sapiens Rho guanine nucleotide ... 38 0.17
AL157713-1|CAH70128.1| 1562|Homo sapiens Rho guanine nucleotide ... 38 0.17
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 38 0.17
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 38 0.17
AB002378-1|BAA20834.2| 1539|Homo sapiens KIAA0380 protein protein. 38 0.17
U02082-1|AAA18010.1| 519|Homo sapiens guanine nucleotide regula... 37 0.23
BC014555-1|AAH14555.1| 519|Homo sapiens ARHGEF5 protein protein. 37 0.23
BC011839-1|AAH11839.1| 519|Homo sapiens ARHGEF5 protein protein. 37 0.23
BC010046-1|AAH10046.1| 519|Homo sapiens ARHGEF5 protein protein. 37 0.23
AK160365-1|BAD18708.1| 1651|Homo sapiens FLJ00261 protein protein. 37 0.23
AC004534-1|AAC12958.1| 519|Homo sapiens guanine nucleotide regu... 37 0.23
AB018336-1|BAA34513.2| 1055|Homo sapiens KIAA0793 protein protein. 37 0.23
AY605091-1|AAT36645.1| 316|Homo sapiens intersectin 1 isoform 7... 36 0.40
U14680-1|AAA73985.1| 1863|Homo sapiens breast and ovarian cancer... 36 0.52
L78833-1|AAC37594.1| 1863|Homo sapiens BRCA1 protein. 36 0.52
DQ478408-3|ABF14462.1| 1822|Homo sapiens early onset breast canc... 36 0.52
DQ190457-3|ABA29229.1| 1822|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190456-3|ABA29226.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190455-3|ABA29223.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190454-3|ABA29220.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190453-3|ABA29217.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190452-3|ABA29214.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190451-3|ABA29211.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
DQ190450-3|ABA29208.1| 1863|Homo sapiens breast cancer 1 early o... 36 0.52
BC099715-1|AAH99715.1| 324|Homo sapiens ARHGEF3 protein protein. 36 0.52
AY751490-1|AAU93634.1| 1841|Homo sapiens breast and ovarian canc... 36 0.52
AY354539-1|AAQ92977.1| 1399|Homo sapiens IRIS protein. 36 0.52
AY304547-1|AAP70031.1| 1141|Homo sapiens breast and ovarian canc... 36 0.52
AY273801-1|AAP12647.1| 1863|Homo sapiens breast cancer 1, early ... 36 0.52
AL732437-4|CAI11032.1| 160|Homo sapiens neuroepithelial cell tr... 36 0.52
AF005068-1|AAB61673.1| 1792|Homo sapiens breast and ovarian canc... 36 0.52
AB209852-1|BAD93089.1| 624|Homo sapiens Neuroepithelial cell tr... 36 0.52
BC132798-1|AAI32799.1| 263|Homo sapiens ret finger protein-like... 35 0.92
BC132796-1|AAI32797.1| 263|Homo sapiens ret finger protein-like... 35 0.92
AY552599-1|AAS59842.1| 871|Homo sapiens SH3-containing guanine ... 35 0.92
AK122906-1|BAC85513.1| 263|Homo sapiens 22D). protein. 35 0.92
AK022884-1|BAB14292.1| 408|Homo sapiens protein ( Homo sapiens ... 35 0.92
AF415175-1|AAL27001.1| 871|Homo sapiens putative SH3 domain-con... 35 0.92
U01147-1|AAC50063.1| 859|Homo sapiens guanine nucleotide regula... 35 1.2
L19704-1|AAC37519.1| 822|Homo sapiens ABR protein. 35 1.2
BC078655-1|AAH78655.1| 871|Homo sapiens Src homology 3 domain-c... 35 1.2
AK126882-1|BAC86734.1| 362|Homo sapiens protein ( Homo sapiens ... 35 1.2
U82939-1|AAC98530.1| 815|Homo sapiens p53 binding protein protein. 34 2.1
BC060884-1|AAH60884.1| 1045|Homo sapiens topoisomerase I binding... 34 2.1
AL353671-4|CAH71253.1| 980|Homo sapiens topoisomerase I binding... 34 2.1
AL353671-3|CAH71254.1| 1045|Homo sapiens topoisomerase I binding... 34 2.1
AF098300-1|AAD23379.1| 1045|Homo sapiens topoisomerase I-binding... 34 2.1
AB045733-1|BAB03715.1| 980|Homo sapiens RING-finger protein pro... 34 2.1
AB045732-1|BAB03714.1| 1045|Homo sapiens RING-finger protein pro... 34 2.1
BX538312-1|CAD98090.1| 695|Homo sapiens hypothetical protein pr... 33 2.8
BC132816-1|AAI32817.1| 1221|Homo sapiens FGD5 protein protein. 33 2.8
BC132814-1|AAI32815.1| 1221|Homo sapiens FGD5 protein protein. 33 2.8
BC035364-1|AAH35364.1| 540|Homo sapiens FGD5 protein protein. 33 2.8
AK131078-1|BAC85128.1| 1386|Homo sapiens FLJ00274 protein protein. 33 2.8
AK097276-1|BAC04989.1| 851|Homo sapiens protein ( Homo sapiens ... 33 2.8
AF180681-1|AAF36817.1| 1544|Homo sapiens guanine nucleotide exch... 33 2.8
AB002380-1|BAA20836.2| 1443|Homo sapiens KIAA0382 protein protein. 33 2.8
AK128530-1|BAC87483.1| 379|Homo sapiens protein ( Homo sapiens ... 33 3.7
AL137002-7|CAM24072.1| 150|Homo sapiens MCF.2 cell line derived... 33 4.9
BC040474-1|AAH40474.1| 380|Homo sapiens ARHGEF10 protein protein. 32 8.5
>BC020208-1|AAH20208.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>BC011853-1|AAH11853.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>AL596093-7|CAI39525.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>AL596093-6|CAI94928.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 630 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 689
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 690 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 747
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 748 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 807
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 808 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 867
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 868 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 926
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 927 EASQHRALEQSQSL 940
>AL596093-4|CAI39524.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 659 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 718
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 719 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 776
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 777 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 836
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 837 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 896
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 897 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 955
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 956 EASQHRALEQSQSL 969
>AL596093-3|CAI39523.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 656 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 715
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 716 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 773
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 774 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 833
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 834 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 893
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 894 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 952
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 953 EASQHRALEQSQSL 966
>AL356740-10|CAH70245.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>AL356740-8|CAI94923.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 630 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 689
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 690 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 747
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 748 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 807
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 808 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 867
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 868 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 926
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 927 EASQHRALEQSQSL 940
>AL356740-6|CAH70244.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 659 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 718
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 719 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 776
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 777 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 836
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 837 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 896
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 897 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 955
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 956 EASQHRALEQSQSL 969
>AL356740-4|CAH70243.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 656 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 715
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 716 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 773
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 774 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 833
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 834 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 893
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 894 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 952
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 953 EASQHRALEQSQSL 966
>AL162454-4|CAI39871.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>AL162454-3|CAI95103.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 630 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 689
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 690 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 747
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 748 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 807
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 808 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 867
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 868 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 926
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 927 EASQHRALEQSQSL 940
>AL162454-2|CAI39870.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 659 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 718
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 719 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 776
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 777 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 836
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 837 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 896
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 897 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 955
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 956 EASQHRALEQSQSL 969
>AL162454-1|CAI39869.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 656 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 715
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 716 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 773
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 774 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 833
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 834 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 893
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 894 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 952
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 953 EASQHRALEQSQSL 966
>AL137002-20|CAI41392.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 624 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 683
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 684 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 741
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 742 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 801
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 802 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 861
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 862 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 920
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 921 EASQHRALEQSQSL 934
>AL137002-18|CAI95400.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 630 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 689
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 690 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 747
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 748 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 807
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 808 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 867
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 868 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 926
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 927 EASQHRALEQSQSL 940
>AL137002-17|CAI41390.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 659 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 718
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 719 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 776
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 777 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 836
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 837 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 896
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 897 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 955
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 956 EASQHRALEQSQSL 969
>AL137002-11|CAI41383.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 656 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 715
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 716 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 773
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 774 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 833
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 834 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 893
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 894 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 952
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 953 EASQHRALEQSQSL 966
>AB116075-1|BAD08352.1| 904|Homo sapiens Ost-I protein.
Length = 904
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 467 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 526
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 527 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 584
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 585 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 644
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 645 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 704
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 705 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 763
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 764 EASQHRALEQSQSL 777
>AB116074-1|BAD08351.1| 1067|Homo sapiens Ost-II protein.
Length = 1067
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 630 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 689
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 690 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 747
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 748 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 807
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 808 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 867
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 868 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 926
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 927 EASQHRALEQSQSL 940
>AB002360-1|BAA20817.1| 1108|Homo sapiens KIAA0362 protein.
Length = 1108
Score = 267 bits (655), Expect = 8e-71
Identities = 145/314 (46%), Positives = 195/314 (62%), Gaps = 11/314 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY E++ P HLL L + DVLFGN+ E++ FH +FL++LE ELV CF+
Sbjct: 671 GYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFL 730
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+ E F ++Y YCQN PRSE L D F Q CQ +L HKL L +YLLKPVQRITK
Sbjct: 731 ERMEDF-QIYEKYCQNKPRSESLWRQCSDCPFF-QECQRKLDHKLSLDSYLLKPVQRITK 788
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK++L+YS LQ+AL +L +LK VNDSMH IAITG +L G+LLMQ
Sbjct: 789 YQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQ 848
Query: 568 GSFLVVSENKXXXXXXXXXX-----XXHIFLYEKAMLFCKPATKN--SHNKA-TYHFKHD 619
GSF V +++K H+FL+EKA+LFCK +N + KA +Y +K
Sbjct: 849 GSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQS 908
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL QL+ +
Sbjct: 909 LNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR- 967
Query: 680 ERVRQYGLQHHRTL 693
E + L+ ++L
Sbjct: 968 EASQHRALEQSQSL 981
>X12556-1|CAA31069.1| 925|Homo sapiens protein ( Human mRNA for dbl
proto-oncogene. ).
Length = 925
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 520 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 579
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 580 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 637
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 638 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 697
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 698 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 757
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 758 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 817
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 818 KKRKQQDQLTERDKFQIS 835
>J03639-1|AAA52172.1| 478|Homo sapiens MCF2 protein.
Length = 478
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 73 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 132
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 133 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 190
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 191 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 250
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 251 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 310
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 311 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 370
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 371 KKRKQQDQLTERDKFQIS 388
>AL161777-3|CAI39715.1| 1070|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 1070
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 665 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 724
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 725 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 782
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 783 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 842
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 843 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 902
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 903 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 962
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 963 KKRKQQDQLTERDKFQIS 980
>AL117234-1|CAB55301.1| 985|Homo sapiens hypothetical protein
protein.
Length = 985
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 580 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 639
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 640 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 697
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 698 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 757
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 758 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 817
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 818 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 877
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 878 KKRKQQDQLTERDKFQIS 895
>AL033403-7|CAA21955.1| 925|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 925
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 520 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 579
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 580 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 637
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 638 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 697
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 698 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 757
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 758 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 817
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 818 KKRKQQDQLTERDKFQIS 835
>AL033403-6|CAI42107.1| 941|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 941
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 536 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 595
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 596 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 653
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 654 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 713
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 714 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 773
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 774 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 833
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 834 KKRKQQDQLTERDKFQIS 851
>AL033403-5|CAI42108.1| 860|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 860
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 520 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 579
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 580 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 637
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 638 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 697
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 698 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 757
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 758 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 817
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 818 KKRKQQDQLTERDKFQIS 835
>AL033403-4|CAI42106.1| 528|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 528
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 123 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 182
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 183 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 240
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 241 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 300
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 301 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 360
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 361 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 420
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 421 KKRKQQDQLTERDKFQIS 438
>AL033403-3|CAI42105.1| 428|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 428
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 23 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 82
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 83 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 140
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 141 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 200
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 201 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 260
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 261 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 320
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 321 KKRKQQDQLTERDKFQIS 338
>AL033403-2|CAI42104.1| 1070|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 1070
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 665 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 724
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 725 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 782
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 783 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 842
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 843 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 902
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 903 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 962
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 963 KKRKQQDQLTERDKFQIS 980
>AB209679-1|BAD92916.1| 435|Homo sapiens MCF.2 cell line derived
transforming sequence variant protein.
Length = 435
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 30 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 89
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 90 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 147
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 148 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 207
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 208 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 267
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 268 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 327
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 328 KKRKQQDQLTERDKFQIS 345
>AB085902-1|BAC41201.1| 941|Homo sapiens DBL proto-oncogene
splicing variant 2 protein.
Length = 941
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 536 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 595
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 596 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 653
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 654 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 713
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 714 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 773
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 774 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 833
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 834 KKRKQQDQLTERDKFQIS 851
>AB085901-1|BAC41200.1| 860|Homo sapiens DBL proto-oncogene
splicing variant 1 protein.
Length = 860
Score = 261 bits (640), Expect = 6e-69
Identities = 139/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 520 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 579
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQRITK
Sbjct: 580 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQRITK 637
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 638 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 697
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 698 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 757
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 758 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 817
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 818 KKRKQQDQLTERDKFQIS 835
>X13230-1|CAA31617.1| 567|Homo sapiens protein ( Human mRNA for
MCF.2 protein 3'-end. ).
Length = 567
Score = 260 bits (636), Expect = 2e-68
Identities = 138/318 (43%), Positives = 196/318 (61%), Gaps = 10/318 (3%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFV 447
GY+ E++ PE L+PP L + D+LFGN+ E++ FH D+FL LE C A E V CF+
Sbjct: 162 GYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFL 221
Query: 448 EKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITK 507
E+++ F ++Y+ YCQN PRSE + + F Q CQ +L H+L L +YLLKPVQ+ITK
Sbjct: 222 ERKDDF-QMYAKYCQNKPRSETIWRKYSEC-AFFQECQRKLKHRLRLDSYLLKPVQQITK 279
Query: 508 YQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQ 567
YQLLLK+LL+YS+ + L++ALD ML +LK VNDSMHQIAI G +L++ G+++MQ
Sbjct: 280 YQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQ 339
Query: 568 GSFLV-----VSENKXXXXXXXXXXXXHIFLYEKAMLFCK---PATKNSHNKATYHFKHD 619
G F V K H+FLYEKA++FCK + + S +Y FKH
Sbjct: 340 GGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHC 399
Query: 620 LLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKG 679
M ++G+TE VKGD RKFE+W + EV+ + A V+VK W++ I+ +LL Q + L
Sbjct: 400 WKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTV 459
Query: 680 ERVRQYGLQHHRTLIQTS 697
++ +Q R Q S
Sbjct: 460 KKRKQQDQLTERDKFQIS 477
>U94190-1|AAC15791.1| 1663|Homo sapiens Duo protein.
Length = 1663
Score = 171 bits (417), Expect = 6e-42
Identities = 103/281 (36%), Positives = 158/281 (56%), Gaps = 13/281 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP ++ + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1318 IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1376
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L F Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1377 KNKPDSNQL--ILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1434
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G L+ L+ ML V K ND+MH + G +L QGEL++Q +F V
Sbjct: 1435 GK--GELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPK----S 1488
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S Y +K+ LL S++G+TE V+GD KF +W
Sbjct: 1489 LIRKGRERHLFLFEISLVFSK-EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALW 1547
Query: 642 --RQGRCEVHTI-TAPTVEVKRAWVERIKRVLLDQLKELKG 679
R + T+ A +E K+ W++ I+ V+ +++ LKG
Sbjct: 1548 SGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKG 1588
>U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein.
Length = 2861
Score = 167 bits (405), Expect = 2e-40
Identities = 101/282 (35%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP +V + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1270 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1328
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1329 KNKPDSTQL--ILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1386
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1387 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1440
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S ++ Y +K L S++G+TE V+GD KF +W
Sbjct: 1441 LIRKGRERHLFLFEMSLVFSK-EVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALW 1499
Query: 642 RQGRCEVH----TITAPTVEVKRAWVERIKRVLLDQLKELKG 679
GR + A ++E K+ W++ I+ V+ ++ LKG
Sbjct: 1500 -VGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKG 1540
Score = 163 bits (397), Expect = 2e-39
Identities = 95/276 (34%), Positives = 159/276 (57%), Gaps = 10/276 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 1945 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 2003
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 2004 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 2061
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
S+ T+ L++A++ M +V + ND M+ + G + QG+LL+Q +FLV ++
Sbjct: 2062 ASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQD---A 2118
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
IFL+E+ ++F +P K + + FK+ + +S + L E+V+ D KF
Sbjct: 2119 GLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFA 2178
Query: 640 VW-RQGR-CEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ R G E + + + V++ W+ I ++L +Q
Sbjct: 2179 LTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQ 2214
>BC035585-1|AAH35585.1| 1627|Homo sapiens Similar to triple functional
domain (PTPRF interacting) protein.
Length = 1627
Score = 167 bits (405), Expect = 2e-40
Identities = 101/282 (35%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP +V + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1270 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1328
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1329 KNKPDSTQL--ILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1386
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1387 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1440
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S ++ Y +K L S++G+TE V+GD KF +W
Sbjct: 1441 LIRKGRERHLFLFEMSLVFSK-EVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALW 1499
Query: 642 RQGRCEVH----TITAPTVEVKRAWVERIKRVLLDQLKELKG 679
GR + A ++E K+ W++ I+ V+ ++ LKG
Sbjct: 1500 -VGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKG 1540
>AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein.
Length = 3038
Score = 167 bits (405), Expect = 2e-40
Identities = 101/282 (35%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP +V + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 1270 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1328
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1329 KNKPDSTQL--ILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1386
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1387 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1440
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S ++ Y +K L S++G+TE V+GD KF +W
Sbjct: 1441 LIRKGRERHLFLFEMSLVFSK-EVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALW 1499
Query: 642 RQGRCEVH----TITAPTVEVKRAWVERIKRVLLDQLKELKG 679
GR + A ++E K+ W++ I+ V+ ++ LKG
Sbjct: 1500 -VGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKG 1540
Score = 163 bits (397), Expect = 2e-39
Identities = 95/276 (34%), Positives = 159/276 (57%), Gaps = 10/276 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 1945 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 2003
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 2004 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 2061
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
S+ T+ L++A++ M +V + ND M+ + G + QG+LL+Q +FLV ++
Sbjct: 2062 ASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQD---A 2118
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
IFL+E+ ++F +P K + + FK+ + +S + L E+V+ D KF
Sbjct: 2119 GLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFA 2178
Query: 640 VW-RQGR-CEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ R G E + + + V++ W+ I ++L +Q
Sbjct: 2179 LTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQ 2214
>AB209754-1|BAD92991.1| 2202|Homo sapiens triple functional domain
(PTPRF interacting) variant protein.
Length = 2202
Score = 167 bits (405), Expect = 2e-40
Identities = 101/282 (35%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP +V + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 968 IPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 1026
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L + Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 1027 KNKPDSTQL--ILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 1084
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
G ++ L+ ML V K ND+MH + G ++ QGEL++Q SF V
Sbjct: 1085 GK--GEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPK----T 1138
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW 641
H+FL+E +++F K K+S ++ Y +K L S++G+TE V+GD KF +W
Sbjct: 1139 LIRKGRERHLFLFEMSLVFSK-EVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALW 1197
Query: 642 RQGRCEVH----TITAPTVEVKRAWVERIKRVLLDQLKELKG 679
GR + A ++E K+ W++ I+ V+ ++ LKG
Sbjct: 1198 -VGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKG 1238
Score = 163 bits (397), Expect = 2e-39
Identities = 95/276 (34%), Positives = 159/276 (57%), Gaps = 10/276 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 1643 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 1701
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 1702 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 1759
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
S+ T+ L++A++ M +V + ND M+ + G + QG+LL+Q +FLV ++
Sbjct: 1760 ASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQD---A 1816
Query: 581 XXXXXXXXXHIFLYEKAMLFCKPA-TKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
IFL+E+ ++F +P K + + FK+ + +S + L E+V+ D KF
Sbjct: 1817 GLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFA 1876
Query: 640 VW-RQGR-CEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ R G E + + + V++ W+ I ++L +Q
Sbjct: 1877 LTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQ 1912
>AK125979-1|BAC86373.1| 738|Homo sapiens (Hapip). protein.
Length = 738
Score = 164 bits (398), Expect = 1e-39
Identities = 94/291 (32%), Positives = 162/291 (55%), Gaps = 13/291 (4%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
++ G+ + IE+ +P + G+ ++FGN+H+++ +H+D FL +LE+CI + +A
Sbjct: 291 IVVEGFMKRIEEKG----VPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLA 346
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F+ K E +Y +YCQN PRSE + + + + + + + +L L+ +L+KP+Q
Sbjct: 347 QLFI-KHERKLHIYVWYCQNKPRSEYI---VAEYDAYFEEVKQEINQRLTLSDFLIKPIQ 402
Query: 504 RITKYQLLLKDLLRYSE-CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
RITKYQLLLKD LRYSE G + +++A++ M +V K ND M+ + G L+ QG
Sbjct: 403 RITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQG 462
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+LL Q +F V+ + +FL+E+ ++F + K S Y FK + M
Sbjct: 463 KLLQQDTFYVI---ELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPG-YMFKRSIKM 518
Query: 623 SQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ + L E+V D KF + + E + A ++++AWV+ I +VL Q
Sbjct: 519 NYLVLEENVDNDPCKFALMNRETSERVVLQAANADIQQAWVQDINQVLETQ 569
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 164 bits (398), Expect = 1e-39
Identities = 94/291 (32%), Positives = 162/291 (55%), Gaps = 13/291 (4%)
Query: 384 LINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA 443
++ G+ + IE+ +P + G+ ++FGN+H+++ +H+D FL +LE+CI + +A
Sbjct: 253 IVVEGFMKRIEEKG----VPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLA 308
Query: 444 LCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQ 503
F+ K E +Y +YCQN PRSE + + + + + + + +L L+ +L+KP+Q
Sbjct: 309 QLFI-KHERKLHIYVWYCQNKPRSEYI---VAEYDAYFEEVKQEINQRLTLSDFLIKPIQ 364
Query: 504 RITKYQLLLKDLLRYSE-CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQG 562
RITKYQLLLKD LRYSE G + +++A++ M +V K ND M+ + G L+ QG
Sbjct: 365 RITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQG 424
Query: 563 ELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLM 622
+LL Q +F V+ + +FL+E+ ++F + K S Y FK + M
Sbjct: 425 KLLQQDTFYVI---ELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPG-YMFKRSIKM 480
Query: 623 SQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
+ + L E+V D KF + + E + A ++++AWV+ I +VL Q
Sbjct: 481 NYLVLEENVDNDPCKFALMNRETSERVVLQAANADIQQAWVQDINQVLETQ 531
>AK125163-1|BAC86068.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ43173 fis, clone FCBBF3007540, weakly similar
to GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS. ).
Length = 320
Score = 156 bits (378), Expect = 3e-37
Identities = 110/323 (34%), Positives = 167/323 (51%), Gaps = 28/323 (8%)
Query: 380 QCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT 439
+C + Y E+E+ + LP L G+ V+FGNL +L FHQ FL++LERC
Sbjct: 13 RCLGYVIDNYFPEMERMD----LPQGLRGKHHVIFGNLEKLHDFHQQHFLRELERCQHCP 68
Query: 440 ELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLL 499
V F+ E F +Y Y +N P+S+ L + + F + Q LG K+ LA+YLL
Sbjct: 69 LAVGRSFLRHEEQF-GMYVIYSKNKPQSDALLSS--HGNAFFKDKQRELGDKMDLASYLL 125
Query: 500 KPVQRITKYQLLLKDLLRYSECG---SMTTGLQQALDCMLVV-LKCVNDSMHQIAITGVP 555
+PVQR+ KY LLL+DLL+ + CG G +A + ++ L+ ND + AI G
Sbjct: 126 RPVQRVAKYALLLQDLLKEASCGLAQGQELGELRAAEVVVCFQLRHGNDLLAMDAIRGCD 185
Query: 556 VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK-PATKNSHNKATY 614
V+L +QG+L + F+V K H+FL+E +LF K + SH+ Y
Sbjct: 186 VNLKEQGQLRCRDEFIVCCGRK--------KYLRHVFLFEDLILFSKTQKVEGSHD--VY 235
Query: 615 HFKHDLLMSQIGLTESVKGDLRKFEVW---RQGRCEVHTITAPTVEVKRAWVERIKRVLL 671
+K ++IG+TE+V +FE+W R+ + + + A + EVK AW + I R+L
Sbjct: 236 LYKQSFKTAEIGMTENVGDSGLRFEIWFRRRRKSQDTYILQASSAEVKSAWTDVIGRILW 295
Query: 672 DQLKELKGER---VRQYGLQHHR 691
Q + +G R RQ L HR
Sbjct: 296 RQALKSRGRRGTPPRQRDLGSHR 318
>AB067496-1|BAB67802.2| 1287|Homo sapiens KIAA1909 protein protein.
Length = 1287
Score = 154 bits (373), Expect = 1e-36
Identities = 105/313 (33%), Positives = 164/313 (52%), Gaps = 25/313 (7%)
Query: 380 QCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISAT 439
+C + Y E+E+ + LP L G+ V+FGNL +L FHQ FL++LERC
Sbjct: 838 RCLGYVIDNYFPEMERMD----LPQGLRGKHHVIFGNLEKLHDFHQQHFLRELERCQHCP 893
Query: 440 ELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLL 499
V F+ E F +Y Y +N P+S+ L + + F + Q LG K+ LA+YLL
Sbjct: 894 LAVGRSFLRHEEQF-GMYVIYSKNKPQSDALLSS--HGNAFFKDKQRELGDKMDLASYLL 950
Query: 500 KPVQRITKYQLLLKDLLRYSECG---SMTTGLQQALDCMLVV-LKCVNDSMHQIAITGVP 555
+PVQR+ KY LLL+DLL+ + CG G +A + ++ L+ ND + AI G
Sbjct: 951 RPVQRVAKYALLLQDLLKEASCGLAQGQELGELRAAEVVVCFQLRHGNDLLAMDAIRGCD 1010
Query: 556 VDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK-PATKNSHNKATY 614
V+L +QG+L + F+V K H+FL+E +LF K + SH+ Y
Sbjct: 1011 VNLKEQGQLRCRDEFIVCCGRK--------KYLRHVFLFEDLILFSKTQKVEGSHD--VY 1060
Query: 615 HFKHDLLMSQIGLTESVKGDLRKFEVW---RQGRCEVHTITAPTVEVKRAWVERIKRVLL 671
+K ++IG+TE+V +FE+W RQ + + + A + EVK AW + I R+L
Sbjct: 1061 LYKQSFKTAEIGMTENVGDSGLRFEIWFRRRQKSQDTYILQASSAEVKSAWTDVIGRILW 1120
Query: 672 DQLKELKGERVRQ 684
Q + + R+++
Sbjct: 1121 RQALKSRELRIQE 1133
>BC012860-1|AAH12860.1| 474|Homo sapiens RAC/CDC42 exchange factor
protein.
Length = 474
Score = 150 bits (363), Expect = 2e-35
Identities = 93/303 (30%), Positives = 164/303 (54%), Gaps = 13/303 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L G+ ++FGN+ +++ +H+D FL++L+RC+ + +A F+ K E +Y YC
Sbjct: 89 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFI-KHERRLHMYVVYC 147
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN P+SE + D+ + + + +LGH+L L L+KPVQRI KYQLLLKD L+ Y+
Sbjct: 148 QNKPKSEHVVSEFGDS--YFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNR 205
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L+QA++ M V K ND M + G L+ QG+LL Q +F V+E +
Sbjct: 206 AGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFW-VTEPEAGG 264
Query: 581 XXXXXXXXXHIFLYEKAMLFCKP--ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+FL+E+ ++F + + Y +K+ + +S +GL +++GD +F
Sbjct: 265 LLSSRGRERRVFLFEQIIIFSEALGGGVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRF 324
Query: 639 EVWR---QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTLIQ 695
+ +G + + + A + +AW++ + ++L Q L Q +++ R Q
Sbjct: 325 ALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFL---NALQSPIEYQRRESQ 381
Query: 696 TSS 698
T+S
Sbjct: 382 TNS 384
>AY172737-1|AAO19651.1| 1031|Homo sapiens Rho family
guanine-nucleotide exchange factor protein.
Length = 1031
Score = 147 bits (356), Expect = 1e-34
Identities = 100/337 (29%), Positives = 168/337 (49%), Gaps = 32/337 (9%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
I + S+I+ GY ++ +HL+P L D LFGN+ EL+ FH FLK+LE+C
Sbjct: 552 IKEIKSIID-GYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAE 610
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
EL+A CF++++E ++Y Y +N+PR+ + + D F CQ +L H LPL Y
Sbjct: 611 NPELLAHCFLKRKED-LQIYFKYHKNLPRARAIWQECQDCAYF-GVCQRQLDHNLPLFKY 668
Query: 498 LLKPVQRITKYQLLLKDLLRY----------SECG-------------SMTTGLQQALDC 534
L P QR+ KYQ+LLK LL + E G + +T LQQAL
Sbjct: 669 LKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELGGSAKDGPKRTKDSAFSTELQQALAV 728
Query: 535 MLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXX----XXXH 590
+ ++K ++ A+T P D+ + G+LL+ G F V + +K
Sbjct: 729 IEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQ 788
Query: 591 IFLYEKAMLFCKPATKNSHNKAT--YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV 648
I+L+E+ ++FCK + + Y FK + + + + + +G RKFE+ + E
Sbjct: 789 IYLFERGIVFCKIRMEPGDQGLSPHYSFKKAMKLMTLSIRQLGRGSHRKFEIASRNGLEK 848
Query: 649 HTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQY 685
+ + A + E++ W I ++L++Q +K + Q+
Sbjct: 849 YILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQF 885
>AB020668-1|BAA74884.1| 982|Homo sapiens KIAA0861 protein protein.
Length = 982
Score = 147 bits (356), Expect = 1e-34
Identities = 100/337 (29%), Positives = 168/337 (49%), Gaps = 32/337 (9%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
I + S+I+ GY ++ +HL+P L D LFGN+ EL+ FH FLK+LE+C
Sbjct: 503 IKEIKSIID-GYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAE 561
Query: 438 ATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAY 497
EL+A CF++++E ++Y Y +N+PR+ + + D F CQ +L H LPL Y
Sbjct: 562 NPELLAHCFLKRKED-LQIYFKYHKNLPRARAIWQECQDCAYF-GVCQRQLDHNLPLFKY 619
Query: 498 LLKPVQRITKYQLLLKDLLRY----------SECG-------------SMTTGLQQALDC 534
L P QR+ KYQ+LLK LL + E G + +T LQQAL
Sbjct: 620 LKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELGGSAKDGPKRTKDSAFSTELQQALAV 679
Query: 535 MLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXX----XXXH 590
+ ++K ++ A+T P D+ + G+LL+ G F V + +K
Sbjct: 680 IEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQ 739
Query: 591 IFLYEKAMLFCKPATKNSHNKAT--YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV 648
I+L+E+ ++FCK + + Y FK + + + + + +G RKFE+ + E
Sbjct: 740 IYLFERGIVFCKIRMEPGDQGLSPHYSFKKAMKLMTLSIRQLGRGSHRKFEIASRNGLEK 799
Query: 649 HTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQY 685
+ + A + E++ W I ++L++Q +K + Q+
Sbjct: 800 YILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQF 836
>BC047559-1|AAH47559.1| 580|Homo sapiens RAC/CDC42 exchange factor
protein.
Length = 580
Score = 146 bits (353), Expect = 3e-34
Identities = 92/303 (30%), Positives = 163/303 (53%), Gaps = 13/303 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L G+ ++FGN+ +++ +H+D FL++L+RC+ + +A F+ K E +Y Y
Sbjct: 195 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFI-KHERRLHMYVVYY 253
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN P+SE + D+ + + + +LGH+L L L+KPVQRI KYQLLLKD L+ Y+
Sbjct: 254 QNKPKSEHVVSEFGDS--YFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNR 311
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L+QA++ M V K ND M + G L+ QG+LL Q +F V+E +
Sbjct: 312 AGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFW-VTEPEAGG 370
Query: 581 XXXXXXXXXHIFLYEKAMLFCKP--ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+FL+E+ ++F + + Y +K+ + +S +GL +++GD +F
Sbjct: 371 LLSSRGRERRVFLFEQIIIFSEALGGRVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRF 430
Query: 639 EVWR---QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTLIQ 695
+ +G + + + A + +AW++ + ++L Q L Q +++ R Q
Sbjct: 431 ALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFL---NALQSPIEYQRRESQ 487
Query: 696 TSS 698
T+S
Sbjct: 488 TNS 490
>AF487514-1|AAO49463.2| 580|Homo sapiens RAC/CDC42/Rho exchange
factor GEFT protein.
Length = 580
Score = 146 bits (353), Expect = 3e-34
Identities = 92/303 (30%), Positives = 163/303 (53%), Gaps = 13/303 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L G+ ++FGN+ +++ +H+D FL++L+RC+ + +A F+ K E +Y Y
Sbjct: 195 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFI-KHERRLHMYVVYY 253
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSE 520
QN P+SE + D+ + + + +LGH+L L L+KPVQRI KYQLLLKD L+ Y+
Sbjct: 254 QNKPKSEHVVSEFGDS--YFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNR 311
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXX 580
G T L+QA++ M V K ND M + G L+ QG+LL Q +F V+E +
Sbjct: 312 AGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFW-VTEPEAGG 370
Query: 581 XXXXXXXXXHIFLYEKAMLFCKP--ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
+FL+E+ ++F + + Y +K+ + +S +GL +++GD +F
Sbjct: 371 LLSSRGRERRVFLFEQIIIFSEALGGRVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRF 430
Query: 639 EVWR---QGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTLIQ 695
+ +G + + + A + +AW++ + ++L Q L Q +++ R Q
Sbjct: 431 ALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFL---NALQSPIEYQRRESQ 487
Query: 696 TSS 698
T+S
Sbjct: 488 TNS 490
>BC054486-1|AAH54486.1| 1110|Homo sapiens PLEKHG4 protein protein.
Length = 1110
Score = 144 bits (349), Expect = 1e-33
Identities = 102/301 (33%), Positives = 152/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 677 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 732
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 733 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 789
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 790 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 847
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 848 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 898
Query: 626 GLTESVKGDLRKFEVWRQGR--CEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W +GR + + A ++ +K+AW I +L Q K R+
Sbjct: 899 GLTECCGNSNLRFEIWFRGRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 958
Query: 684 Q 684
+
Sbjct: 959 E 959
>BC082974-1|AAH82974.1| 1151|Homo sapiens PLEKHG4 protein protein.
Length = 1151
Score = 142 bits (343), Expect = 5e-33
Identities = 101/301 (33%), Positives = 151/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 718 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 773
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 774 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 830
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 831 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 888
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 889 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 939
Query: 626 GLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W R+ + + A ++ +K+AW I +L Q K R+
Sbjct: 940 GLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 999
Query: 684 Q 684
+
Sbjct: 1000 E 1000
>BC063501-1|AAH63501.1| 1191|Homo sapiens PLEKHG4 protein protein.
Length = 1191
Score = 142 bits (343), Expect = 5e-33
Identities = 101/301 (33%), Positives = 151/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 758 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 813
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 814 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 870
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 871 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 928
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 929 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 979
Query: 626 GLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W R+ + + A ++ +K+AW I +L Q K R+
Sbjct: 980 GLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 1039
Query: 684 Q 684
+
Sbjct: 1040 E 1040
>AK024475-1|BAB15765.1| 1194|Homo sapiens FLJ00068 protein protein.
Length = 1194
Score = 142 bits (343), Expect = 5e-33
Identities = 101/301 (33%), Positives = 151/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 761 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 816
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 817 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 873
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 874 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 931
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 932 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 982
Query: 626 GLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W R+ + + A ++ +K+AW I +L Q K R+
Sbjct: 983 GLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 1042
Query: 684 Q 684
+
Sbjct: 1043 E 1043
>AB197663-1|BAE07054.1| 1191|Homo sapiens puratrophin-1 protein.
Length = 1191
Score = 142 bits (343), Expect = 5e-33
Identities = 101/301 (33%), Positives = 151/301 (50%), Gaps = 23/301 (7%)
Query: 389 YKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVE 448
Y E+++P+ +P L GQ LFGNL +L FH FL++LE C VA F+
Sbjct: 758 YFPELDRPD----VPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLR 813
Query: 449 KRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKY 508
R F +Y+ Y +N PRS+ L + H F + Q LG L LA+YLLKP+QR+ KY
Sbjct: 814 HRVQF-GMYALYSKNKPRSDALMSSY--GHTFFKDKQQALGDHLDLASYLLKPIQRMGKY 870
Query: 509 QLLLKDLLRYSECGSMT---TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELL 565
LLL++L R CG T + L++A + L+ ND + AI G V+L +QG+L+
Sbjct: 871 ALLLQELAR--ACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLV 928
Query: 566 MQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQI 625
Q F+V IFL+E+ +LF KP T+ +K M+ +
Sbjct: 929 RQDEFVV--------RTGRHKSVRRIFLFEELLLFSKP-RHGPTGVDTFAYKRSFKMADL 979
Query: 626 GLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVR 683
GLTE +FE+W R+ + + A ++ +K+AW I +L Q K R+
Sbjct: 980 GLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMA 1039
Query: 684 Q 684
+
Sbjct: 1040 E 1040
>AL137002-4|CAM24069.1| 312|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 312
Score = 138 bits (333), Expect = 9e-32
Identities = 76/174 (43%), Positives = 108/174 (62%), Gaps = 9/174 (5%)
Query: 528 LQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXX 587
LQ+AL +L +LK VNDSMH IAITG +L G+LLMQGSF V +++K
Sbjct: 2 LQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELA 61
Query: 588 XX-----HIFLYEKAMLFCKPATKNS--HNKA-TYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+EKA+LFCK +N + KA +Y +K L M+ +G+TE+VKGD +KFE
Sbjct: 62 RFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFE 121
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTL 693
+W R EV+ + APT E+K AWV I++VL QL+ + E + L+ ++L
Sbjct: 122 IWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACR-EASQHRALEQSQSL 174
>AL137002-5|CAM24070.1| 316|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 316
Score = 130 bits (314), Expect = 2e-29
Identities = 72/166 (43%), Positives = 102/166 (61%), Gaps = 9/166 (5%)
Query: 536 LVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXX-----H 590
L +LK VNDSMH IAITG +L G+LLMQGSF V +++K H
Sbjct: 1 LGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRH 60
Query: 591 IFLYEKAMLFCKPATKNS--HNKA-TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCE 647
+FL+EKA+LFCK +N + KA +Y +K L M+ +G+TE+VKGD +KFE+W R E
Sbjct: 61 LFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREE 120
Query: 648 VHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTL 693
V+ + APT E+K AWV I++VL QL+ + E + L+ ++L
Sbjct: 121 VYIVQAPTPEIKAAWVNEIRKVLTSQLQACR-EASQHRALEQSQSL 165
>AB115332-1|BAC79392.1| 255|Homo sapiens transforming gene product
TGAT protein.
Length = 255
Score = 125 bits (301), Expect = 7e-28
Identities = 62/147 (42%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + G+ ++FGN+H+++ +H+D FL +LE+C+ E + FV K E +Y YC
Sbjct: 84 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFV-KHERRLHMYIAYC 142
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + +DT F + + RLGH+L L L+KPVQRI KYQLLLKD L+YS+
Sbjct: 143 QNKPKSEHIVSEYIDT--FFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKK 200
Query: 522 GSM-TTGLQQALDCMLVVLKCVNDSMH 547
S+ T+ L++A++ M +V + ND M+
Sbjct: 201 ASLDTSELERAVEVMCIVPRRCNDMMN 227
>AL137629-1|CAB70850.1| 381|Homo sapiens hypothetical protein
protein.
Length = 381
Score = 123 bits (296), Expect = 3e-27
Identities = 73/219 (33%), Positives = 120/219 (54%), Gaps = 8/219 (3%)
Query: 456 LYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
+Y +YCQN PRSE + + + + + + + +L L+ +L+KP+QRITKYQLLLKD
Sbjct: 1 IYVWYCQNKPRSEYI---VAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDF 57
Query: 516 LRYSE-CGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
LRYSE G + +++A++ M +V K ND M+ + G L+ QG+LL Q +F V+
Sbjct: 58 LRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVI- 116
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
+ +FL+E+ ++F + K S Y FK + M+ + L E+V D
Sbjct: 117 --ELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPG-YMFKRSIKMNYLVLEENVDND 173
Query: 635 LRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQ 673
KF + + E + A ++++AWV+ I +VL Q
Sbjct: 174 PCKFALMNRETSERVVLQAANADIQQAWVQDINQVLETQ 212
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 113 bits (271), Expect = 3e-24
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 11/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 344 VPIAVAGQKAVIFRNVRDIGRFHSSSFLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 402
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 403 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 462
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 463 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 521
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 522 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 581
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 582 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 615
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 113 bits (271), Expect = 3e-24
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 11/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 344 VPIAVAGQKAVIFRNVRDIGRFHSSSFLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 402
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 403 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 462
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 463 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 521
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 522 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 581
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 582 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 615
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 113 bits (271), Expect = 3e-24
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 11/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 344 VPIAVAGQKAVIFRNVRDIGRFHSSSFLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 402
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 403 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 462
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 463 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 521
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 522 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 581
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 582 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 615
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 109 bits (262), Expect = 4e-23
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 5786
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 5905
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 5906 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 5965
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 5966 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 5999
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 109 bits (262), Expect = 4e-23
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 5786
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 5905
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 5906 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 5965
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 5966 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 5999
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 109 bits (262), Expect = 4e-23
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 5786
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 5905
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 5906 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 5965
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 5966 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 5999
>AK131379-1|BAD18530.1| 851|Homo sapiens protein ( Homo sapiens
cDNA FLJ16443 fis, clone BRAMY3004800, highly similar
to Huntingtin-associated protein-interacting protein. ).
Length = 851
Score = 109 bits (262), Expect = 4e-23
Identities = 62/152 (40%), Positives = 89/152 (58%), Gaps = 5/152 (3%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+PP ++ + ++FGN+ E++ FH ++FLK+LE+ E V CFV + F++Y YC
Sbjct: 664 IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADK-FQMYVTYC 722
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
+N P S +L L F Q R G +++YL+KPVQRITKYQLLLK+LL E
Sbjct: 723 KNKPDSNQL--ILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEE 780
Query: 522 GSMTTGLQQALDCMLVVLKCVNDSMHQIAITG 553
G L+ L+ ML V K ND+MH + G
Sbjct: 781 GK--GELKDGLEVMLSVPKKANDAMHVSMLEG 810
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 109 bits (262), Expect = 4e-23
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 129 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 186
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 187 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 246
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 247 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 305
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 306 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 365
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 366 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 399
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 109 bits (262), Expect = 4e-23
Identities = 73/274 (26%), Positives = 129/274 (47%), Gaps = 12/274 (4%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P + GQ V+F N+ ++ FH FL++L++C + + VA+CF++ + F + +
Sbjct: 5729 VPIAVAGQKAVIFRNVRDIGRFHSS-FLQELQQCDTDDD-VAMCFIKNQAAFEQYLEFLV 5786
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKL------PLAAYLLKPVQRITKYQLLLKDL 515
+ + T + A + L PL YL +PV+R+ +YQ LLK+L
Sbjct: 5787 GRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKEL 5846
Query: 516 LRYSECGSMTTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVS 574
+R L +QA + + + + +H + P L GE + QG F +V
Sbjct: 5847 IRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHF-IVW 5905
Query: 575 ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGD 634
E H+FL+ ++ CKP + + +Y F++ + +S I L + V+GD
Sbjct: 5906 EGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGD 5965
Query: 635 LRKFEVW--RQGRCEVHTITAPTVEVKRAWVERI 666
R FEVW R+ + + A T +K +WV+ I
Sbjct: 5966 DRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEI 5999
>BC129953-1|AAI29954.1| 1219|Homo sapiens PLEKHG3 protein protein.
Length = 1219
Score = 108 bits (259), Expect = 8e-23
Identities = 87/280 (31%), Positives = 134/280 (47%), Gaps = 34/280 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRS- 467
Q LFGN+ ++ + + L+DL+ C S VA CFVE+ + F +Y+ YC N P S
Sbjct: 134 QVSALFGNIENIYALNSQL-LRDLDSCNSDPVAVASCFVERSQEF-DIYTQYCNNYPNSV 191
Query: 468 ERLRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSM 524
L E + D F + Q L H LPL +YLLKPVQRI KY LLL+++ + + E
Sbjct: 192 AALTECMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAKHFDEEEDG 251
Query: 525 TTGLQQALDCMLVVLKCVND------------SMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ A+D M V +ND + + I DL+ GEL+++G+F V
Sbjct: 252 FEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEGTFRV 311
Query: 573 VSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVK 632
FL++K +L K + H + +K ++ S + L ES +
Sbjct: 312 HRVRNERT----------FFLFDKTLLITK--KRGDH----FVYKGNIPCSSLMLIESTR 355
Query: 633 GDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
L + + ++I A TVE KR W IKR++L+
Sbjct: 356 DSLCFTVTHYKHSKQQYSIQAKTVEEKRNWTHHIKRLILE 395
>AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 106 bits (255), Expect = 2e-22
Identities = 87/283 (30%), Positives = 140/283 (49%), Gaps = 39/283 (13%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
+ LFGN+ +++ F+ ++ L+DLE C + +A CFV K E F +Y+ YC N PRS
Sbjct: 155 ERSALFGNIQDIYHFNSEL-LQDLENCENDPVAIAECFVSKSEEF-HIYTQYCTNYPRSV 212
Query: 469 R-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
L E + + L F + Q L H LPL +YLLKPVQRI KY LLL ++ + + T
Sbjct: 213 AVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLD--KDT 270
Query: 526 TG---LQQALDCMLVVLKCVND--SMHQIAITGVPV----------DLSQQGELLMQGSF 570
G + A+D M V +ND H+ A+ + DL+ GEL+++G+F
Sbjct: 271 EGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTF 330
Query: 571 LVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTES 630
+ +FL++K +L K T+ +K +L + L E
Sbjct: 331 RIQRAKNERT----------LFLFDKLLLITK------KRDDTFTYKAHILCGNLMLVEV 374
Query: 631 VKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRVLLD 672
+ + F V+ ++ HT+ A + + KR WV +KR++L+
Sbjct: 375 IPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILE 417
>AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 106 bits (255), Expect = 2e-22
Identities = 87/283 (30%), Positives = 140/283 (49%), Gaps = 39/283 (13%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
+ LFGN+ +++ F+ ++ L+DLE C + +A CFV K E F +Y+ YC N PRS
Sbjct: 155 ERSALFGNIQDIYHFNSEL-LQDLENCENDPVAIAECFVSKSEEF-HIYTQYCTNYPRSV 212
Query: 469 R-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
L E + + L F + Q L H LPL +YLLKPVQRI KY LLL ++ + + T
Sbjct: 213 AVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLD--KDT 270
Query: 526 TG---LQQALDCMLVVLKCVND--SMHQIAITGVPV----------DLSQQGELLMQGSF 570
G + A+D M V +ND H+ A+ + DL+ GEL+++G+F
Sbjct: 271 EGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTF 330
Query: 571 LVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTES 630
+ +FL++K +L K T+ +K +L + L E
Sbjct: 331 RIQRAKNERT----------LFLFDKLLLITK------KRDDTFTYKAHILCGNLMLVEV 374
Query: 631 VKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRVLLD 672
+ + F V+ ++ HT+ A + + KR WV +KR++L+
Sbjct: 375 IPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILE 417
>AK057416-1|BAB71477.1| 306|Homo sapiens protein ( Homo sapiens
cDNA FLJ32854 fis, clone TESTI2003498, moderately
similar to TRIPLE FUNCTIONAL DOMAIN PROTEIN. ).
Length = 306
Score = 103 bits (248), Expect = 2e-21
Identities = 50/125 (40%), Positives = 79/125 (63%), Gaps = 3/125 (2%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
+P +L G+ ++FGN+ +++ +H+D FL++L+RC+ + +A F+ K E +Y YC
Sbjct: 69 VPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFI-KHERRLHMYVVYC 127
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSEC 521
QN P+SE + D+ + + + +LGH+L L L+KPVQRI KYQLLLKD L+Y
Sbjct: 128 QNKPKSEHVVSEFGDS--YFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNR 185
Query: 522 GSMTT 526
M T
Sbjct: 186 AGMDT 190
>BC107066-1|AAI07067.1| 296|Homo sapiens BRSK2 protein protein.
Length = 296
Score = 93.1 bits (221), Expect = 3e-18
Identities = 46/106 (43%), Positives = 70/106 (66%), Gaps = 4/106 (3%)
Query: 591 IFLYEKAMLFCKPATKNS--HNKA-TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCE 647
+FL+EKA+LFCK +N + KA +Y +K L M+ +G+TE+VKGD +KFE+W R E
Sbjct: 3 LFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREE 62
Query: 648 VHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTL 693
V+ + APT E+K AWV I++VL QL+ + E + L+ ++L
Sbjct: 63 VYIVQAPTPEIKAAWVNEIRKVLTSQLQACR-EASQHRALEQSQSL 107
>BC075858-1|AAH75858.1| 1253|Homo sapiens PLEKHG2 protein protein.
Length = 1253
Score = 88.6 bits (210), Expect = 7e-17
Identities = 85/285 (29%), Positives = 134/285 (47%), Gaps = 33/285 (11%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
V Q LF N+ +++ F ++ L+DLE SA +A CFV++ E F +Y+ YC N P
Sbjct: 38 VEQVGTLFANIEDIYEFSSEL-LEDLENSSSAGG-IAECFVQRSEDF-DIYTLYCMNYPS 94
Query: 467 S-ERLRETLVD--THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
S LRE + L+LQ Q +L H LPL ++LLKPVQRI KY LLL++L ++ G
Sbjct: 95 SLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGP 154
Query: 524 MTTG---LQQALDCMLVVLKCVND----SMHQIAITGVP--------VDLSQQGELLMQG 568
T G +++A+ M V +ND H + V +LS GEL+++G
Sbjct: 155 GTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEG 214
Query: 569 SFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLT 628
+F +FL+ + +L K Y +K + + ++
Sbjct: 215 AF----RGGGGGGPRLRGGERLLFLFSRMLLVAK------RRGLEYTYKGHIFCCNLSVS 264
Query: 629 ESVKGDLRKFEVWRQG-RCEVHTITAPTVEVKRAWVERIKRVLLD 672
ES + L F+V H + A E KR W+ ++R+ +
Sbjct: 265 ESPRDPL-GFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFE 308
>AK024429-1|BAB15719.1| 1430|Homo sapiens FLJ00018 protein protein.
Length = 1430
Score = 88.6 bits (210), Expect = 7e-17
Identities = 85/285 (29%), Positives = 134/285 (47%), Gaps = 33/285 (11%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPR 466
V Q LF N+ +++ F ++ L+DLE SA +A CFV++ E F +Y+ YC N P
Sbjct: 186 VEQVGTLFANIEDIYEFSSEL-LEDLENSSSAGG-IAECFVQRSEDF-DIYTLYCMNYPS 242
Query: 467 S-ERLRETLVD--THLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGS 523
S LRE + L+LQ Q +L H LPL ++LLKPVQRI KY LLL++L ++ G
Sbjct: 243 SLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGP 302
Query: 524 MTTG---LQQALDCMLVVLKCVND----SMHQIAITGVP--------VDLSQQGELLMQG 568
T G +++A+ M V +ND H + V +LS GEL+++G
Sbjct: 303 GTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEG 362
Query: 569 SFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLT 628
+F +FL+ + +L K Y +K + + ++
Sbjct: 363 AF----RGGGGGGPRLRGGERLLFLFSRMLLVAK------RRGLEYTYKGHIFCCNLSVS 412
Query: 629 ESVKGDLRKFEVWRQG-RCEVHTITAPTVEVKRAWVERIKRVLLD 672
ES + L F+V H + A E KR W+ ++R+ +
Sbjct: 413 ESPRDPL-GFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFE 456
>AL137291-1|CAB70682.1| 658|Homo sapiens hypothetical protein
protein.
Length = 658
Score = 88.2 bits (209), Expect = 9e-17
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
L P L G L +FH+ FL++L+ C + + CF+ + F S Y
Sbjct: 275 LTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQF----SLYA 330
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-- 519
Q + +L L + + G LP A L +P++++T+Y LL++LLR +
Sbjct: 331 QYVKHRHKLENGLAALSPSSKG-SMEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGP 387
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
E S L A+ + D + A+ G +DL +QG+LL + F V+ K
Sbjct: 388 ELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK-- 445
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+E +LF K ++ + +K + +GLTE++ FE
Sbjct: 446 ------KCLRHVFLFEHLLLFSKLKGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFE 498
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ E +T+ A + E+K W I ++L Q K RV+Q
Sbjct: 499 LWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQ 545
>AK074057-1|BAB84883.1| 1546|Homo sapiens FLJ00128 protein protein.
Length = 1546
Score = 88.2 bits (209), Expect = 9e-17
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
L P L G L +FH+ FL++L+ C + + CF+ + F S Y
Sbjct: 1142 LTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQF----SLYA 1197
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-- 519
Q + +L L + + G LP A L +P++++T+Y LL++LLR +
Sbjct: 1198 QYVKHRHKLENGLAALSPSSKG-SMEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGP 1254
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
E S L A+ + D + A+ G +DL +QG+LL + F V+ K
Sbjct: 1255 ELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK-- 1312
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+E +LF K ++ + +K + +GLTE++ FE
Sbjct: 1313 ------KCLRHVFLFEHLLLFSKLKGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFE 1365
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ E +T+ A + E+K W I ++L Q K RV+Q
Sbjct: 1366 LWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQ 1412
>AK024463-1|BAB15753.1| 1310|Homo sapiens FLJ00056 protein protein.
Length = 1310
Score = 88.2 bits (209), Expect = 9e-17
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 20/287 (6%)
Query: 402 LPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYC 461
L P L G L +FH+ FL++L+ C + + CF+ + F S Y
Sbjct: 906 LTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQF----SLYA 961
Query: 462 QNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS-- 519
Q + +L L + + G LP A L +P++++T+Y LL++LLR +
Sbjct: 962 QYVKHRHKLENGLAALSPSSKG-SMEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGP 1018
Query: 520 ECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXX 579
E S L A+ + D + A+ G +DL +QG+LL + F V+ K
Sbjct: 1019 ELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK-- 1076
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
H+FL+E +LF K ++ + +K + +GLTE++ FE
Sbjct: 1077 ------KCLRHVFLFEHLLLFSKLKGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFE 1129
Query: 640 VW--RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQ 684
+W R+ E +T+ A + E+K W I ++L Q K RV+Q
Sbjct: 1130 LWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQ 1176
>BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein.
Length = 1192
Score = 78.6 bits (185), Expect = 8e-14
Identities = 71/238 (29%), Positives = 113/238 (47%), Gaps = 37/238 (15%)
Query: 454 FRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F +Y+ YC N PRS L E + + L F + Q L H LPL +YLLKPVQRI KY L
Sbjct: 5 FHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHL 64
Query: 511 LLKDLLRYSECGSMTTG---LQQALDCMLVVLKCVND--SMHQIAITGVPV--------- 556
LL ++ + + T G + A+D M V +ND H+ A+ +
Sbjct: 65 LLHEIENHLD--KDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKG 122
Query: 557 -DLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYH 615
DL+ GEL+++G+F + +FL++K +L K T+
Sbjct: 123 PDLTSYGELVLEGTFRIQRAKNERT----------LFLFDKLLLITK------KRDDTFT 166
Query: 616 FKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRVLLD 672
+K +L + L E + + F V+ ++ HT+ A + + KR WV +KR++L+
Sbjct: 167 YKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILE 224
>AY508997-1|AAS82572.1| 979|Homo sapiens P-Rex2B protein.
Length = 979
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ ++ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 72 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKF-RIYDEYCSNHEKA 129
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY L+LK+LL R
Sbjct: 130 QKLLLELNKIRTIRTFLLNCMLLGGRKNIDVPLEGYLVTPIQRICKYPLILKELLKRTPR 189
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S + +AL M V +N++ Q+
Sbjct: 190 KHSDYAAVMEALQAMKAVCSNINEAKRQM 218
>AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein.
Length = 1606
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ ++ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 72 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKF-RIYDEYCSNHEKA 129
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY L+LK+LL R
Sbjct: 130 QKLLLELNKIRTIRTFLLNCMLLGGRKNIDVPLEGYLVTPIQRICKYPLILKELLKRTPR 189
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S + +AL M V +N++ Q+
Sbjct: 190 KHSDYAAVMEALQAMKAVCSNINEAKRQM 218
>AL137002-6|CAM24071.1| 335|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 335
Score = 75.4 bits (177), Expect = 7e-13
Identities = 34/81 (41%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Query: 613 TYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+Y +K L M+ +G+TE+VKGD +KFE+W R EV+ + APT E+K AWV I++VL
Sbjct: 11 SYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTS 70
Query: 673 QLKELKGERVRQYGLQHHRTL 693
QL+ + E + L+ ++L
Sbjct: 71 QLQACR-EASQHRALEQSQSL 90
>AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein.
Length = 1606
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 13/149 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ ++ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 72 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKF-RIYDEYCSNHEKA 129
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY L+LK+LL R
Sbjct: 130 QKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPR 189
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDSMHQI 549
S + +AL M V +N++ Q+
Sbjct: 190 KHSDYAAVMEALQAMKAVCSNINEAKRQM 218
>AY570973-1|AAS59407.1| 205|Homo sapiens PtdIns(3,4,5)-dependent
rac exchanger-2 protein.
Length = 205
Score = 73.3 bits (172), Expect = 3e-12
Identities = 50/145 (34%), Positives = 79/145 (54%), Gaps = 13/145 (8%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI----SATELVALCFVEKRETFFRLYSYYCQNIPRS 467
+LF N+ ++ H++ FLK +E C+ +A + V CF+ ++ F R+Y YC N ++
Sbjct: 63 MLFSNIEDILAVHKE-FLKVVEECLHPEPNAQQEVGTCFLHFKDKF-RIYDEYCSNHEKA 120
Query: 468 ERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLL-RYSE 520
++L L + T FL C L G K +PL YL+ P+QRI KY L+LK+LL R
Sbjct: 121 QKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPR 180
Query: 521 CGSMTTGLQQALDCMLVVLKCVNDS 545
S + +AL M V +N++
Sbjct: 181 KHSDYAAVMEALQAMKAVCSNINEA 205
>BC000084-1|AAH00084.3| 326|Homo sapiens FLJ10357 protein protein.
Length = 326
Score = 70.9 bits (166), Expect = 2e-11
Identities = 58/203 (28%), Positives = 97/203 (47%), Gaps = 15/203 (7%)
Query: 486 LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS--ECGSMTTGLQQALDCMLVVLKCVN 543
+ G LP A L +P++++T+Y LL++LLR + E S L A+ +
Sbjct: 1 MEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLREQEARGR 58
Query: 544 DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKP 603
D + A+ G +DL +QG+LL + F V+ K H+FL+E +LF K
Sbjct: 59 DLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK--------KCLRHVFLFEHLLLFSKL 110
Query: 604 ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRA 661
++ + +K + +GLTE++ FE+W R+ E +T+ A + E+K
Sbjct: 111 KGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLK 169
Query: 662 WVERIKRVLLDQLKELKGERVRQ 684
W I ++L Q K RV+Q
Sbjct: 170 WTSSIAQLLWRQAAHNKELRVQQ 192
>AK001219-1|BAA91563.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ10357 fis, clone NT2RM2001221, weakly similar to
KALIRIN. ).
Length = 278
Score = 70.9 bits (166), Expect = 2e-11
Identities = 58/203 (28%), Positives = 97/203 (47%), Gaps = 15/203 (7%)
Query: 486 LRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS--ECGSMTTGLQQALDCMLVVLKCVN 543
+ G LP A L +P++++T+Y LL++LLR + E S L A+ +
Sbjct: 1 MEAGPYLPRA--LQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLREQEARGR 58
Query: 544 DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKP 603
D + A+ G +DL +QG+LL + F V+ K H+FL+E +LF K
Sbjct: 59 DLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRK--------KCLRHVFLFEHLLLFSKL 110
Query: 604 ATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVW--RQGRCEVHTITAPTVEVKRA 661
++ + +K + +GLTE++ FE+W R+ E +T+ A + E+K
Sbjct: 111 KGPEGGSE-MFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLK 169
Query: 662 WVERIKRVLLDQLKELKGERVRQ 684
W I ++L Q K RV+Q
Sbjct: 170 WTSSIAQLLWRQAAHNKELRVQQ 192
>BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein.
Length = 790
Score = 70.1 bits (164), Expect = 3e-11
Identities = 62/253 (24%), Positives = 116/253 (45%), Gaps = 24/253 (9%)
Query: 366 DYDRR---LEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFT 422
+YD+R L + T + + + S ++ KP + L P + +++F N+ +L
Sbjct: 136 EYDKRCCCLREIQQTEEKYTDTLGS-IQQHFLKPLQRFLKPQDI----EIIFINIEDLLR 190
Query: 423 FHQDVFLKDLERCISATELVAL--CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVD 476
H FLK+++ + L F++ +E F +Y YC + + +R+ D
Sbjct: 191 VHTH-FLKEMKEALGTPGAANLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVAAARED 248
Query: 477 THLFLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCM 535
+ L+ C R + + L L+ P+QR+ KY LLL++L+++++ L+ ALD M
Sbjct: 249 VQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAM 308
Query: 536 LVVLKCV------NDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXX 589
+ +CV N+++ QI + ++ Q L G + E K
Sbjct: 309 RDLAQCVNEVKRDNETLRQITNFQLSIENLDQ-SLAHYGRPKIDGELKITSVERRSKMDR 367
Query: 590 HIFLYEKAMLFCK 602
+ FL +KA+L CK
Sbjct: 368 YAFLLDKALLICK 380
>AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein.
Length = 845
Score = 70.1 bits (164), Expect = 3e-11
Identities = 62/253 (24%), Positives = 116/253 (45%), Gaps = 24/253 (9%)
Query: 366 DYDRR---LEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFT 422
+YD+R L + T + + + S ++ KP + L P + +++F N+ +L
Sbjct: 191 EYDKRCCCLREIQQTEEKYTDTLGS-IQQHFLKPLQRFLKPQDI----EIIFINIEDLLR 245
Query: 423 FHQDVFLKDLERCISATELVAL--CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVD 476
H FLK+++ + L F++ +E F +Y YC + + +R+ D
Sbjct: 246 VHTH-FLKEMKEALGTPGAANLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVAAARED 303
Query: 477 THLFLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCM 535
+ L+ C R + + L L+ P+QR+ KY LLL++L+++++ L+ ALD M
Sbjct: 304 VQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAM 363
Query: 536 LVVLKCV------NDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXX 589
+ +CV N+++ QI + ++ Q L G + E K
Sbjct: 364 RDLAQCVNEVKRDNETLRQITNFQLSIENLDQ-SLAHYGRPKIDGELKITSVERRSKMDR 422
Query: 590 HIFLYEKAMLFCK 602
+ FL +KA+L CK
Sbjct: 423 YAFLLDKALLICK 435
>AF249745-1|AAF79955.1| 720|Homo sapiens RhoGEF protein.
Length = 720
Score = 66.1 bits (154), Expect = 4e-10
Identities = 81/320 (25%), Positives = 148/320 (46%), Gaps = 34/320 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISA-----TELVALCFVEKRETFFRLYSYYCQN 463
Q +FGN+ +++ Q F+K LE+ + +EL A CF+E + F++YS YC N
Sbjct: 292 QLRTIFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGA-CFLE-HQADFQIYSEYCNN 348
Query: 464 IPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + E R T + ++ F +AC+L + + L +LL PVQ+I KY L L +LL+Y+
Sbjct: 349 HPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYT 408
Query: 520 ECGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ AL M V + +N +++ +IA ++ + +LL++ S L+
Sbjct: 409 HPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELI 468
Query: 573 VS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV 631
S E FL++ +++CK K+ + ++K L M + + +
Sbjct: 469 YSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLDMDGLEVVDLE 525
Query: 632 KG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
G DL F + R + H + E K+ W++ R QL + G +
Sbjct: 526 DGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSI 585
Query: 683 RQYGLQHHRTLIQTSSWEVS 702
+ LQ + ++ S +V+
Sbjct: 586 TE--LQRKQAMLNASKQQVT 603
>AC009477-1|AAX93134.1| 547|Homo sapiens unknown protein.
Length = 547
Score = 66.1 bits (154), Expect = 4e-10
Identities = 81/320 (25%), Positives = 148/320 (46%), Gaps = 34/320 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISA-----TELVALCFVEKRETFFRLYSYYCQN 463
Q +FGN+ +++ Q F+K LE+ + +EL A CF+E + F++YS YC N
Sbjct: 182 QLRTIFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGA-CFLE-HQADFQIYSEYCNN 238
Query: 464 IPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + E R T + ++ F +AC+L + + L +LL PVQ+I KY L L +LL+Y+
Sbjct: 239 HPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYT 298
Query: 520 ECGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ AL M V + +N +++ +IA ++ + +LL++ S L+
Sbjct: 299 HPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELI 358
Query: 573 VS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV 631
S E FL++ +++CK K+ + ++K L M + + +
Sbjct: 359 YSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLDMDGLEVVDLE 415
Query: 632 KG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
G DL F + R + H + E K+ W++ R QL + G +
Sbjct: 416 DGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSI 475
Query: 683 RQYGLQHHRTLIQTSSWEVS 702
+ LQ + ++ S +V+
Sbjct: 476 TE--LQRKQAMLNASKQQVT 493
>AB042199-1|BAB11941.1| 619|Homo sapiens APC-stimulated guanine
nucleotide exchange factor protein.
Length = 619
Score = 66.1 bits (154), Expect = 4e-10
Identities = 81/320 (25%), Positives = 148/320 (46%), Gaps = 34/320 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISA-----TELVALCFVEKRETFFRLYSYYCQN 463
Q +FGN+ +++ Q F+K LE+ + +EL A CF+E + F++YS YC N
Sbjct: 254 QLRTIFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGA-CFLE-HQADFQIYSEYCNN 310
Query: 464 IPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + E R T + ++ F +AC+L + + L +LL PVQ+I KY L L +LL+Y+
Sbjct: 311 HPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYT 370
Query: 520 ECGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ AL M V + +N +++ +IA ++ + +LL++ S L+
Sbjct: 371 HPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELI 430
Query: 573 VS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV 631
S E FL++ +++CK K+ + ++K L M + + +
Sbjct: 431 YSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLDMDGLEVVDLE 487
Query: 632 KG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
G DL F + R + H + E K+ W++ R QL + G +
Sbjct: 488 DGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSI 547
Query: 683 RQYGLQHHRTLIQTSSWEVS 702
+ LQ + ++ S +V+
Sbjct: 548 TE--LQRKQAMLNASKQQVT 565
>AB029035-1|BAA83064.1| 694|Homo sapiens KIAA1112 protein protein.
Length = 694
Score = 66.1 bits (154), Expect = 4e-10
Identities = 81/320 (25%), Positives = 148/320 (46%), Gaps = 34/320 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISA-----TELVALCFVEKRETFFRLYSYYCQN 463
Q +FGN+ +++ Q F+K LE+ + +EL A CF+E + F++YS YC N
Sbjct: 349 QLRTIFGNIEDIYRC-QKAFVKALEQRFNRERPHLSELGA-CFLE-HQADFQIYSEYCNN 405
Query: 464 IPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
P + E R T + ++ F +AC+L + + L +LL PVQ+I KY L L +LL+Y+
Sbjct: 406 HPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYT 465
Query: 520 ECGSMT-TGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGSFLV 572
++ AL M V + +N +++ +IA ++ + +LL++ S L+
Sbjct: 466 HPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELI 525
Query: 573 VS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESV 631
S E FL++ +++CK K+ + ++K L M + + +
Sbjct: 526 YSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLDMDGLEVVDLE 582
Query: 632 KG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD-QLKELKGERV 682
G DL F + R + H + E K+ W++ R QL + G +
Sbjct: 583 DGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSI 642
Query: 683 RQYGLQHHRTLIQTSSWEVS 702
+ LQ + ++ S +V+
Sbjct: 643 TE--LQRKQAMLNASKQQVT 660
>BC109291-1|AAI09292.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 279 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 336
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 337 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 395
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 396 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 454
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 455 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 511
>BC109290-1|AAI09291.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 279 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 336
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 337 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 395
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 396 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 454
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 455 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 511
>AL445192-1|CAI39886.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 98 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 152
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 153 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 212
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 213 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 244
>AL359736-2|CAH72290.2| 574|Homo sapiens spermatogenesis associated
13 protein.
Length = 574
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 201 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 258
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 259 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 317
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 318 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 376
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 377 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 433
>AL359736-1|CAH72289.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 279 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 336
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 337 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 395
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 396 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 454
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 455 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 511
>AL133342-1|CAI23274.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 98 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 152
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 153 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 212
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 213 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 244
>AL035106-1|CAI43186.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 98 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 152
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 153 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 212
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 213 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 244
>AK160371-1|BAD18714.1| 527|Homo sapiens FLJ00298 protein protein.
Length = 527
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 154 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 211
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 212 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 270
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 271 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 329
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 330 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 386
>AK055770-1|BAB71009.1| 652|Homo sapiens factor. protein.
Length = 652
Score = 65.7 bits (153), Expect = 6e-10
Identities = 67/240 (27%), Positives = 115/240 (47%), Gaps = 24/240 (10%)
Query: 407 VGQADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQ 462
V Q +FGN+ +++ F Q FLKDLE+ + E + CF++ +E F +YS YC
Sbjct: 279 VAQLATIFGNIEDIYKF-QRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGF-AIYSEYCN 336
Query: 463 NIPRSERLRETLVDT---HLFLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLR 517
N P + L+ F +AC+L L + +A +LL PVQ+I KY L L +LL+
Sbjct: 337 NHPGACLELANLMKQGKYRHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 395
Query: 518 YS--ECGSMTTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQGELLMQGS 569
Y+ E G + ++ A + M V +N +S+ +IA V + + ++L + S
Sbjct: 396 YTTQEHGDY-SNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSS 454
Query: 570 FLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTE 629
L+ S FL++ ++ CK K+ + ++K L M ++ L +
Sbjct: 455 ELIHSGELTKITKQGKSQQRTFFLFDHQLVSCK---KDLLRRDMLYYKGRLDMDEMELVD 511
>AJ320261-1|CAC86401.1| 1659|Homo sapiens P-Rex1 protein protein.
Length = 1659
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 98 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 152
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 153 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 212
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 213 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 244
>AB037836-1|BAA92653.2| 1621|Homo sapiens KIAA1415 protein protein.
Length = 1621
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/152 (36%), Positives = 77/152 (50%), Gaps = 19/152 (12%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI-----SATEL--VALCFVEKRETFFRLYSYYCQNI 464
VLF N+ ++ H+D FL LE C+ S EL V L F +K F +Y YC N
Sbjct: 60 VLFSNIEDILEVHKD-FLAALEYCLHPEPQSQHELGNVFLKFKDK----FCVYEEYCSNH 114
Query: 465 PRSERLRETL--VDT-HLFLQACQLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLRY 518
++ RL L + T FL +C L G K +PL YLL P+QRI KY LLLK+L +
Sbjct: 115 EKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKR 174
Query: 519 SECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+ +Q AL M V +N++ Q+
Sbjct: 175 TPGKHPDHPAVQSALQAMKTVCSNINETKRQM 206
>AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 113 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 172
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 173 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 231
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 232 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 291
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 292 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 344
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 345 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 403
Query: 667 KRVL 670
+ L
Sbjct: 404 EMAL 407
>AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 113 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 172
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 173 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 231
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 232 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 291
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 292 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 344
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 345 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 403
Query: 667 KRVL 670
+ L
Sbjct: 404 EMAL 407
>AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 64.5 bits (150), Expect = 1e-09
Identities = 68/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isoform
protein.
Length = 753
Score = 64.1 bits (149), Expect = 2e-09
Identities = 68/304 (22%), Positives = 130/304 (42%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 113 YTETLESIEKHFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 172
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + +T D L L+ C R + K L L+
Sbjct: 173 VFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLV 231
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 232 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 291
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A + CK N
Sbjct: 292 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAAIVCKRKGDN------ 344
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 345 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 403
Query: 667 KRVL 670
+ L
Sbjct: 404 EMAL 407
>BC029074-1|AAH29074.2| 271|Homo sapiens MCF2L2 protein protein.
Length = 271
Score = 63.3 bits (147), Expect = 3e-09
Identities = 40/164 (24%), Positives = 79/164 (48%), Gaps = 6/164 (3%)
Query: 528 LQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXX- 586
LQQAL + ++K ++ A+T P D+ + G+LL+ G F V + +K
Sbjct: 2 LQQALAVIEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKDRYKMKDLIR 61
Query: 587 ---XXXHIFLYEKAMLFCKPATKNSHNKAT--YHFKHDLLMSQIGLTESVKGDLRKFEVW 641
I+L+E+ ++FCK + + Y FK + + + + + +G RKFE+
Sbjct: 62 FKPSQRQIYLFERGIVFCKIRMEPGDQGLSPHYSFKKAMKLMTLSIRQLGRGSHRKFEIA 121
Query: 642 RQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQY 685
+ E + + A + E++ W I ++L++Q +K + Q+
Sbjct: 122 SRNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQF 165
>AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 62.9 bits (146), Expect = 4e-09
Identities = 67/304 (22%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
Query: 389 YKEEIEKPENQHLLPPT---LVGQADVLFGNLHELFTFHQDVFLKDLERCISATEL-VAL 444
Y E +E E + P + D +F N+ EL H+++ + + ++ + +
Sbjct: 207 YTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQ 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRS----ERLRETLVDTHLFLQACQLRLGH-KLPLAAYLL 499
F+ +E +Y YC + + + + ++ D L L+ C R + K L L+
Sbjct: 267 VFINYKERLV-IYGQYCSGVESAISSLDYISKSKEDVKLKLEECSKRANNGKFTLRDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCV------NDSMHQIAITG 553
P+QR+ KY LLL++L++++ + L+ ALD M + + V N+++ +I
Sbjct: 326 VPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQ 385
Query: 554 VPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
+ ++ Q LL G E + HIFL++ A++ CK N
Sbjct: 386 LSIENLNQPVLLF-GRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKGDN------ 438
Query: 614 YHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHT-------ITAPTVEVKRAWVERI 666
Y K + + Q + + D ++ + W G +HT T ++K+ W+E+
Sbjct: 439 YEMKEIIDLQQYKIANNPTTD-KENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQF 497
Query: 667 KRVL 670
+ L
Sbjct: 498 EMAL 501
>AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marker 4
protein.
Length = 2063
Score = 61.7 bits (143), Expect = 9e-09
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS---ATELVAL 444
GY + +++PEN L P+LV D +F + EL H+ FL+ + C+ A + V
Sbjct: 1091 GYMQPLKQPENSVLCDPSLV---DEIFDQIPELLEHHEQ-FLEQVRHCMQTWHAQQKVGA 1146
Query: 445 CFVEK--RETFFRLYSYYCQNIPRSE---RLRETLVDTHL-FLQACQLRLGHKLPLAAYL 498
V+ ++ +YS Y N ++ R+ + L FL+ K L+ +
Sbjct: 1147 LLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLM 1206
Query: 499 LKPVQRITKYQLLLKDLLRYS 519
+KPVQRI +Y+LL+KDLL+++
Sbjct: 1207 IKPVQRIPRYELLVKDLLKHT 1227
>AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein.
Length = 1609
Score = 61.7 bits (143), Expect = 9e-09
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Query: 388 GYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS---ATELVAL 444
GY + +++PEN L P+LV D +F + EL H+ FL+ + C+ A + V
Sbjct: 637 GYMQPLKQPENSVLCDPSLV---DEIFDQIPELLEHHEQ-FLEQVRHCMQTWHAQQKVGA 692
Query: 445 CFVEK--RETFFRLYSYYCQNIPRSE---RLRETLVDTHL-FLQACQLRLGHKLPLAAYL 498
V+ ++ +YS Y N ++ R+ + L FL+ K L+ +
Sbjct: 693 LLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLM 752
Query: 499 LKPVQRITKYQLLLKDLLRYS 519
+KPVQRI +Y+LL+KDLL+++
Sbjct: 753 IKPVQRIPRYELLVKDLLKHT 773
>Z85987-1|CAI42222.1| 961|Homo sapiens FYVE, RhoGEF and PH domain
containing 1 (faciogenital dysplasia) protein.
Length = 961
Score = 60.9 bits (141), Expect = 2e-08
Identities = 73/306 (23%), Positives = 132/306 (43%), Gaps = 33/306 (10%)
Query: 393 IEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKR 450
+E+ N+ P +V +F N+ ++ FHQ L +LE+ + + ++K
Sbjct: 404 LEEARNRSSFPADVVHG---IFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKL 460
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTH-----LFLQACQLRLGHKLPLAAYLLKPVQRI 505
F ++Y Y +N R+ L T + + + + L L ++L+PVQRI
Sbjct: 461 APFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRI 520
Query: 506 TKYQLLLKD-LLRYSECGSMTTGLQQALDCMLVVLKCVN------DSMHQI----AITGV 554
+Y+LLLKD LL+ + Q++L+ + + N + MH++ + G
Sbjct: 521 PRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGG 580
Query: 555 PVDL-SQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
D+ S EL+ +G L +S ++ L+ +L+C P + K +
Sbjct: 581 EEDIVSPTKELIKEGHILKLSAKN------GTTQDRYLILFNDRLLYCVPRLRLLGQKFS 634
Query: 614 YHFKHDLLMSQIGLTESVKGDL-RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+ D + + L ES +L R F V G+ + A T E K+ WV+ I LL
Sbjct: 635 VRARID--VDGMELKESSNLNLPRTFLV--SGKQRSLELQARTEEEKKDWVQAINSTLLK 690
Query: 673 QLKELK 678
+ L+
Sbjct: 691 HEQTLE 696
>U11690-1|AAA57004.1| 961|Homo sapiens FGD1 protein.
Length = 961
Score = 60.9 bits (141), Expect = 2e-08
Identities = 73/306 (23%), Positives = 132/306 (43%), Gaps = 33/306 (10%)
Query: 393 IEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKR 450
+E+ N+ P +V +F N+ ++ FHQ L +LE+ + + ++K
Sbjct: 404 LEEARNRSSFPADVVHG---IFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKL 460
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTH-----LFLQACQLRLGHKLPLAAYLLKPVQRI 505
F ++Y Y +N R+ L T + + + + L L ++L+PVQRI
Sbjct: 461 APFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRI 520
Query: 506 TKYQLLLKD-LLRYSECGSMTTGLQQALDCMLVVLKCVN------DSMHQI----AITGV 554
+Y+LLLKD LL+ + Q++L+ + + N + MH++ + G
Sbjct: 521 PRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGG 580
Query: 555 PVDL-SQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
D+ S EL+ +G L +S ++ L+ +L+C P + K +
Sbjct: 581 EEDIVSPTKELIKEGHILKLSAKN------GTTQDRYLILFNDRLLYCVPRLRLLGQKFS 634
Query: 614 YHFKHDLLMSQIGLTESVKGDL-RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+ D + + L ES +L R F V G+ + A T E K+ WV+ I LL
Sbjct: 635 VRARID--VDGMELKESSNLNLPRTFLV--SGKQRSLELQARTEEEKKDWVQAINSTLLK 690
Query: 673 QLKELK 678
+ L+
Sbjct: 691 HEQTLE 696
>BC064632-1|AAH64632.1| 711|Homo sapiens MCF2L2 protein protein.
Length = 711
Score = 60.9 bits (141), Expect = 2e-08
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Query: 378 ISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCIS 437
I + S+I+ GY ++ +HL+P L D LFGN+ EL+ FH FLK+LE+C
Sbjct: 635 IKEIKSIID-GYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAE 693
Query: 438 ATELVALCFVEK 449
EL+A CF+++
Sbjct: 694 NPELLAHCFLKR 705
>BC034530-1|AAH34530.1| 961|Homo sapiens FYVE, RhoGEF and PH domain
containing 1 (faciogenital dysplasia) protein.
Length = 961
Score = 60.9 bits (141), Expect = 2e-08
Identities = 73/306 (23%), Positives = 132/306 (43%), Gaps = 33/306 (10%)
Query: 393 IEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKR 450
+E+ N+ P +V +F N+ ++ FHQ L +LE+ + + ++K
Sbjct: 404 LEEARNRSSFPADVVHG---IFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKL 460
Query: 451 ETFFRLYSYYCQNIPRSERLRETLVDTH-----LFLQACQLRLGHKLPLAAYLLKPVQRI 505
F ++Y Y +N R+ L T + + + + L L ++L+PVQRI
Sbjct: 461 APFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRI 520
Query: 506 TKYQLLLKD-LLRYSECGSMTTGLQQALDCMLVVLKCVN------DSMHQI----AITGV 554
+Y+LLLKD LL+ + Q++L+ + + N + MH++ + G
Sbjct: 521 PRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGG 580
Query: 555 PVDL-SQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKAT 613
D+ S EL+ +G L +S ++ L+ +L+C P + K +
Sbjct: 581 EEDIVSPTKELIKEGHILKLSAKN------GTTQDRYLILFNDRLLYCVPRLRLLGQKFS 634
Query: 614 YHFKHDLLMSQIGLTESVKGDL-RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD 672
+ D + + L ES +L R F V G+ + A T E K+ WV+ I LL
Sbjct: 635 VRARID--VDGMELKESSNLNLPRTFLV--SGKQRSLELQARTEEEKKDWVQAINSTLLK 690
Query: 673 QLKELK 678
+ L+
Sbjct: 691 HEQTLE 696
>BC117406-1|AAI17407.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 144 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 201
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 202 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 260
>AL451106-3|CAI39552.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 142 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 199
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 200 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 258
>AL451106-1|CAI39550.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 144 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 201
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 202 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 260
>AL391277-3|CAI40403.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 142 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 199
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 200 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 258
>AL391277-2|CAI40402.1| 495|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 495
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 123 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 180
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 181 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 239
>AL391277-1|CAI40401.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 144 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 201
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 202 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 260
>AL355142-3|CAI41197.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 142 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 199
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 200 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 258
>AL355142-2|CAI41196.1| 495|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 495
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 123 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 180
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 181 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 239
>AL355142-1|CAI41195.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 144 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 201
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 202 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 260
>AB007884-1|BAA24854.2| 567|Homo sapiens KIAA0424 protein.
Length = 567
Score = 60.5 bits (140), Expect = 2e-08
Identities = 40/120 (33%), Positives = 69/120 (57%), Gaps = 12/120 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATEL----VALCFVEKRETFFRLYSYYCQN- 463
Q V+FGN+ +++ F F++DLE+ + + + CF+E ++ F+ +YS YC N
Sbjct: 195 QLKVIFGNIEDIYRFQMG-FVRDLEKQYNNDDPHLSEIGPCFLEHQDGFW-IYSEYCNNH 252
Query: 464 IPRSERLRETLVDTHL--FLQACQLRLGHKLPLA--AYLLKPVQRITKYQLLLKDLLRYS 519
+ L + + D+ F +AC+L L + +A +LL PVQ+I KY L L +LL+Y+
Sbjct: 253 LDACMELSKLMKDSRYQHFFEACRL-LQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYT 311
>AL160264-1|CAI20471.1| 697|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 697
Score = 59.7 bits (138), Expect = 4e-08
Identities = 43/159 (27%), Positives = 75/159 (47%), Gaps = 12/159 (7%)
Query: 367 YDRRLEQWCDTISQCSSLINSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQD 426
Y RL +S S + ++E ++ + P +V V+F N+ ++ FH
Sbjct: 117 YVARLHLLDQAMSDLSWRLQVFFQELLKTARSSKAFPEDVVR---VIFSNISSIYQFHSQ 173
Query: 427 VFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQA 483
FL +L+R + +A + ++K F ++YS Y +N R+ L T D Q
Sbjct: 174 FFLPELQRRLDDWTANPRIG-DVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSPLFQE 232
Query: 484 CQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
R+ L L ++L+PVQRI +Y+LLLK+ ++
Sbjct: 233 VLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQ 271
>BC053655-1|AAH53655.1| 655|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 655
Score = 58.0 bits (134), Expect = 1e-07
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
V+F N+ ++ FH FL +L+R + +A + ++K F ++YS Y +N R+
Sbjct: 149 VIFSNISSIYQFHSQFFLPELQRRLDDWTANPRIG-DVIQKLAPFLKMYSEYVKNFERAA 207
Query: 469 RLRETLVDTHLFLQACQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
L T D Q R+ L L ++L+PVQRI +Y+LLLK+ ++
Sbjct: 208 ELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQ 261
>BC023645-1|AAH23645.1| 655|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 655
Score = 58.0 bits (134), Expect = 1e-07
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 412 VLFGNLHELFTFHQDVFLKDLERCI---SATELVALCFVEKRETFFRLYSYYCQNIPRSE 468
V+F N+ ++ FH FL +L+R + +A + ++K F ++YS Y +N R+
Sbjct: 149 VIFSNISSIYQFHSQFFLPELQRRLDDWTANPRIG-DVIQKLAPFLKMYSEYVKNFERAA 207
Query: 469 RLRETLVDTHLFLQACQLRL-----GHKLPLAAYLLKPVQRITKYQLLLKDLLR 517
L T D Q R+ L L ++L+PVQRI +Y+LLLK+ ++
Sbjct: 208 ELLATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQ 261
>BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>AL357934-1|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 208 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 266
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 267 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 325
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 326 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 385
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 386 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 439
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 440 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 498
Query: 668 RVL 670
+
Sbjct: 499 MAM 501
>S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein.
Length = 878
Score = 56.0 bits (129), Expect = 5e-07
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 213 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 271
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 272 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 330
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 331 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 390
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+I + V L + G + G E K ++FL++K ++ CK
Sbjct: 391 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCK 438
>AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 56.0 bits (129), Expect = 5e-07
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 213 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 271
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 272 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 330
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 331 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 390
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+I + V L + G + G E K ++FL++K ++ CK
Sbjct: 391 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCK 438
>AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 56.0 bits (129), Expect = 5e-07
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 213 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 271
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 272 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 330
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 331 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 390
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+I + V L + G + G E K ++FL++K ++ CK
Sbjct: 391 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCK 438
>AL357934-2|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 56.0 bits (129), Expect = 5e-07
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLKDLERCISAT-ELVAL 444
Y +E E ++ P LV AD+ +F NL +L H FL+ ++ + +A
Sbjct: 213 YYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHS-FLRAIDVSVMVGGSTLAK 271
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 272 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 330
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 331 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 390
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCK 602
+I + V L + G + G E K ++FL++K ++ CK
Sbjct: 391 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCK 438
>DQ424905-1|ABD83670.1| 630|Homo sapiens rho guanine nucleotide
exchange factor 4 variant 1 protein.
Length = 630
Score = 55.6 bits (128), Expect = 6e-07
Identities = 66/270 (24%), Positives = 123/270 (45%), Gaps = 26/270 (9%)
Query: 454 FRLYSYYCQNIPRS--ERLRETLVDTHL-FLQACQL-RLGHKLPLAAYLLKPVQRITKYQ 509
F++YS YC N P + E R T + ++ F +AC+L + + L +LL PVQ+I KY
Sbjct: 312 FQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYP 371
Query: 510 LLLKDLLRYSECGSM-TTGLQQALDCMLVVLKCVN------DSMHQIAITGVPVDLSQQG 562
L L +LL+Y+ + ++ AL M V + +N +++ +IA ++ +
Sbjct: 372 LQLAELLKYTHPQHRDSKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGE 431
Query: 563 ELLMQGSFLVVS-ENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLL 621
+LL++ S L+ S E FL++ +++CK K+ + ++K L
Sbjct: 432 DLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCK---KDLLRRDVLYYKGRLD 488
Query: 622 MSQIGLTESVKG---DL-----RKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLD- 672
M + + + G DL F + R + H + E K+ W++ R
Sbjct: 489 MDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQV 548
Query: 673 QLKELKGERVRQYGLQHHRTLIQTSSWEVS 702
QL + G + + LQ + ++ S +V+
Sbjct: 549 QLDQETGFSITE--LQRKQAMLNASKQQVT 576
>AK026111-1|BAB15364.1| 384|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22458 fis, clone HRC10001. ).
Length = 384
Score = 55.2 bits (127), Expect = 8e-07
Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 27/210 (12%)
Query: 479 LFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTG---LQQALDCM 535
L+LQ Q +L H LPL ++LLKPVQRI KY LLL++L ++ G T G +++A+ M
Sbjct: 21 LWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPGTGGREMVEEAIVSM 80
Query: 536 LVVLKCVND----SMHQIAITGVP--------VDLSQQGELLMQGSFLVVSENKXXXXXX 583
V +ND H + V +LS GEL+++G+F
Sbjct: 81 TAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEGAF----RGGGGGGPR 136
Query: 584 XXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQ 643
+FL+ + +L K Y +K + + ++ES + L F+V
Sbjct: 137 LRGGERLLFLFSRMLLVAK------RRGLEYTYKGHIFCCNLSVSESPRDPL-GFKVSDL 189
Query: 644 G-RCEVHTITAPTVEVKRAWVERIKRVLLD 672
H + A E KR W+ ++R+ +
Sbjct: 190 TIPKHRHLLQAKNQEEKRLWIHCLQRLFFE 219
>BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein
protein.
Length = 801
Score = 54.4 bits (125), Expect = 1e-06
Identities = 70/303 (23%), Positives = 126/303 (41%), Gaps = 30/303 (9%)
Query: 389 YKEEIEKPENQHLLPPTLV-GQADV--LFGNLHELFTFHQDVFLK-DLERCISATELVAL 444
Y +E E ++ P LV AD+ + NL +L H + D+ + + L A
Sbjct: 170 YYRTLEDIEKNYMSPLRLVLSPADMAAVLINLEDLIKVHHSLLRAIDVSVMVGGSTL-AK 228
Query: 445 CFVEKRETFFRLYSYYCQNIPRSER-LRETLVDTHLFLQA---CQLRLGH-KLPLAAYLL 499
F++ +E +Y YC ++ ++ L + L F Q C L++ K L L+
Sbjct: 229 VFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLV 287
Query: 500 KPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVND-----------SMHQ 548
P+QR+ KY LLLK+LL +S L++AL+ M + +N+ S Q
Sbjct: 288 VPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQ 347
Query: 549 IAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNS 608
+I + V L + G + G E K ++FL++K ++ CK +
Sbjct: 348 SSIENLQVKLEEFGRPKIDG------ELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSY 401
Query: 609 HNKATYHFK-HDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIK 667
K H + + + K + + QG+ + T ++KR W+E+ +
Sbjct: 402 ELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGK-QGFQFFCKTEDMKRKWMEQFE 460
Query: 668 RVL 670
+
Sbjct: 461 MAM 463
>X83931-1|CAA58783.1| 539|Homo sapiens VAV protein.
Length = 539
Score = 52.8 bits (121), Expect = 4e-06
Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 8/134 (5%)
Query: 476 DTHLFLQACQLRLGH-KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDC 534
D + L+ C R + + L L+ P+QR+ KY LLL++L+++++ L+ ALD
Sbjct: 5 DVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDA 64
Query: 535 MLVVLKCV------NDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXXXXXXX 588
M + +CV N+++ QI + ++ Q L G + E K
Sbjct: 65 MRDLAQCVNEVKRDNETLRQITNFQLSIENLDQ-SLAHYGRPKIDGELKITSVERRSKMD 123
Query: 589 XHIFLYEKAMLFCK 602
+ FL +KA+L CK
Sbjct: 124 RYAFLLDKALLICK 137
>BC117196-1|AAI17197.1| 1591|Homo sapiens T-cell lymphoma invasion and
metastasis 1 protein.
Length = 1591
Score = 52.4 bits (120), Expect = 6e-06
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLE---RCISATELVALCFVEKRETF------------ 453
+ DVLFGNL E+ F + FLK LE R + E + K+ F
Sbjct: 1080 ELDVLFGNLTEMVEFQVE-FLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADR 1138
Query: 454 FRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C + + + L + DT FL A + H L +YL+KP+QRI KY L
Sbjct: 1139 FKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPL 1198
Query: 511 LLKDLLRYSECGS 523
LL++L ++ S
Sbjct: 1199 LLRELFALTDAES 1211
>BC117192-1|AAI17193.1| 1591|Homo sapiens T-cell lymphoma invasion and
metastasis 1 protein.
Length = 1591
Score = 52.4 bits (120), Expect = 6e-06
Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLE---RCISATELVALCFVEKRETF------------ 453
+ DVLFGNL E+ F + FLK LE R + E + K+ F
Sbjct: 1080 ELDVLFGNLTEMVEFQVE-FLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADR 1138
Query: 454 FRLYSYYCQNIPRSER-LRETLVDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C + + + L + DT FL A + H L +YL+KP+QRI KY L
Sbjct: 1139 FKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPL 1198
Query: 511 LLKDLLRYSECGS 523
LL++L ++ S
Sbjct: 1199 LLRELFALTDAES 1211
>U16296-1|AAA98443.1| 1591|Homo sapiens TIAM1 protein protein.
Length = 1591
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 19/133 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLE---RCISATELVALCFVEKRETF------------ 453
+ DVLFGNL E+ F + FLK LE R + E + K+ F
Sbjct: 1080 ELDVLFGNLTEMVEFQVE-FLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADR 1138
Query: 454 FRLYSYYCQ---NIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C +P+ +T FL A + H L +YL+KP+QRI KY L
Sbjct: 1139 FKLYSAFCAIHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPL 1198
Query: 511 LLKDLLRYSECGS 523
LL++L ++ S
Sbjct: 1199 LLRELFALTDAES 1211
>BC032429-1|AAH32429.1| 725|Homo sapiens FGD3 protein protein.
Length = 725
Score = 50.4 bits (115), Expect = 2e-05
Identities = 58/272 (21%), Positives = 118/272 (43%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLF---LQACQLR-LGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + Q + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVIHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>AL596202-1|CAI14404.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 484 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 541
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 542 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 601
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 602 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 637
>AL355343-1|CAH73978.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 484 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 541
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 542 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 601
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 602 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 637
>AL139101-3|CAI20508.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 484 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 541
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 542 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 601
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 602 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 637
>AK000004-1|BAA92229.1| 698|Homo sapiens FLJ00004 protein protein.
Length = 698
Score = 50.4 bits (115), Expect = 2e-05
Identities = 58/272 (21%), Positives = 118/272 (43%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 264 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 323
Query: 470 LRETLVD-THLF---LQACQLR-LGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + Q + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 324 LVSTWTQRSPLFKDVIHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 383
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 384 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 443
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 444 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 501
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 502 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 532
>AF120324-1|AAF05901.1| 626|Homo sapiens T-cell lymphoma invasion
and metastasis 2 short protein.
Length = 626
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 64 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 121
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 122 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 181
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 182 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 217
>AF120323-1|AAF05900.1| 1077|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1077
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 515 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 572
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 573 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 632
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 633 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 668
>AB209674-1|BAD92911.1| 1947|Homo sapiens T-cell lymphoma invasion and
metastasis 2 variant protein.
Length = 1947
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 1385 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 1442
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 1443 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 1502
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 1503 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 1538
>AB095936-1|BAC23112.2| 1715|Homo sapiens KIAA2016 protein protein.
Length = 1715
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/156 (33%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F Q VFL+ LE ISA+ L +L F+ +
Sbjct: 1153 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 1210
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 1211 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 1270
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 1271 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 1306
>BC111054-1|AAI11055.1| 725|Homo sapiens FGD3 protein protein.
Length = 725
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLFLQAC----QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>AY211386-1|AAP20645.1| 634|Homo sapiens FGD3 protein.
Length = 634
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLFLQAC----QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>AL451065-1|CAI95107.1| 725|Homo sapiens FYVE, RhoGEF and PH domain
containing 3 protein.
Length = 725
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLFLQAC----QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>AL389924-2|CAI41118.1| 725|Homo sapiens FYVE, RhoGEF and PH domain
containing 3 protein.
Length = 725
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 17/272 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISA---TELVALCFVEKRETFFRLYSYYCQNIPRSER 469
+F N+ + FH L +L+ I+ T ++K F ++Y Y +N R+
Sbjct: 200 IFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVG 259
Query: 470 LRETLVD-THLFLQAC----QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL-RYSECGS 523
L T + LF + + L L ++L+PVQR+ +Y+LLLKD L R +
Sbjct: 260 LVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAP 319
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIA----ITGVPVDLSQQGELLMQGSFLVVS-ENKX 578
+++L+ + N ++ ++ + V L + +++ + L+ + +
Sbjct: 320 DRKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQK 379
Query: 579 XXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKF 638
H+FL+ +L+C P + K + K D+ S + + + VK +
Sbjct: 380 LSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDI--SGLQVQDIVKPNTAHT 437
Query: 639 EVWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
+ GR + T E K+ W++ I+ +
Sbjct: 438 FI-ITGRKRSLELQTRTEEEKKEWIQIIQATI 468
>AK125459-1|BAC86170.1| 1268|Homo sapiens protein ( Homo sapiens
cDNA FLJ43470 fis, clone OCBBF2037547, highly similar
to Homo sapiens T-cell lymphoma invasion and metastasis
2 (TIAM2). ).
Length = 1268
Score = 50.0 bits (114), Expect = 3e-05
Identities = 51/155 (32%), Positives = 74/155 (47%), Gaps = 20/155 (12%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISAT----------ELVALCFVEKRETF----- 453
+ + LFG+L E+ F Q VFL+ LE ISA+ + L F
Sbjct: 677 EMESLFGSLPEMLEF-QKVFLETLEDGISASSDFNTLETPSQFRKLLFPLGGSFLYYADH 735
Query: 454 FRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQL 510
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY L
Sbjct: 736 FKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPL 795
Query: 511 LLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLK+L+ ++ S L +AL M V +N+
Sbjct: 796 LLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 830
>BC066979-1|AAH66979.1| 626|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 626
Score = 49.2 bits (112), Expect = 5e-05
Identities = 51/156 (32%), Positives = 77/156 (49%), Gaps = 22/156 (14%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCISATE--------------LVAL--CFVEKRET 452
+ + LFG+L E+ F + VFL+ LE ISA+ L +L F+ +
Sbjct: 64 EMESLFGSLPEMLEFRK-VFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD- 121
Query: 453 FFRLYSYYCQNIPRSERLRE---TLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQ 509
F+LYS +C N + +++ E T FL A H L +YL+KPVQR+ KY
Sbjct: 122 HFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYP 181
Query: 510 LLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVND 544
LLLK+L+ ++ S L +AL M V +N+
Sbjct: 182 LLLKELVSLTDQESEEHYHLTEALKAMEKVASHINE 217
>BC036749-1|AAH36749.1| 841|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 15 protein.
Length = 841
Score = 49.2 bits (112), Expect = 5e-05
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETF--FRLYSYYCQNIPRSERL 470
LF N+ + + L R S+ + LC V F +Y Y +N E
Sbjct: 461 LFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEET 520
Query: 471 RETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG-SM 524
L+DT++ A RL +LPL ++LL P QRIT+ ++LL+++LR +E G S
Sbjct: 521 YSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSR 580
Query: 525 TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
Q+AL + +++ + + ++ T + L+Q+
Sbjct: 581 QENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQR 617
>AY367054-1|AAQ72372.1| 280|Homo sapiens actin-filament binding
protein frabin protein.
Length = 280
Score = 49.2 bits (112), Expect = 5e-05
Identities = 52/275 (18%), Positives = 119/275 (43%), Gaps = 16/275 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSERL 470
+F N+ + FH L +LE+ + E ++K F ++Y Y + + L
Sbjct: 5 IFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYAKGFDNAMEL 64
Query: 471 RETLVDT-----HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + + + + ++ L L ++L+PVQRI +Y++LLKD LR S+
Sbjct: 65 VKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLD 124
Query: 526 -TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ---QGELLMQGSFLVVSENK--XX 579
+++L+ + N ++ ++ +++ + + E ++ S ++ E +
Sbjct: 125 WNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKL 184
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
++FL+ +L+C P +K T + + +I T++ + F+
Sbjct: 185 AARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYP-HTFQ 243
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQL 674
V G+ + A + + K W++R +L +L
Sbjct: 244 V--SGKERTLELQASSAQDKEEWIKRRGFAMLPRL 276
>AB020722-1|BAA74938.2| 846|Homo sapiens KIAA0915 protein protein.
Length = 846
Score = 49.2 bits (112), Expect = 5e-05
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETF--FRLYSYYCQNIPRSERL 470
LF N+ + + L R S+ + LC V F +Y Y +N E
Sbjct: 466 LFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEET 525
Query: 471 RETLVDTHLFLQACQLRLG-----HKLPLAAYLLKPVQRITKYQLLLKDLLRYSECG-SM 524
L+DT++ A RL +LPL ++LL P QRIT+ ++LL+++LR +E G S
Sbjct: 526 YSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSR 585
Query: 525 TTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
Q+AL + +++ + + ++ T + L+Q+
Sbjct: 586 QENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQR 622
>D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein.
Length = 802
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 293 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 351
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 352 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 403
>BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein.
Length = 803
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 315 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 373
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 374 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 425
>BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 764
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 255 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 313
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 314 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 365
>BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein.
Length = 753
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 265 LMGNLEEICSFQQ-MLVQSLEECTKLPEAKQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 323
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 324 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 375
>AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein
protein.
Length = 812
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 324 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 382
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 383 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 434
>AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 137 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 195
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 196 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 247
>AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant 2
protein.
Length = 680
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 171 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 229
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 230 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 281
>AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant 1
protein.
Length = 691
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCIS---ATELVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GNL E+ +F Q + ++ LE C A + V CF+ LY YC N P +
Sbjct: 293 LMGNLEEICSFQQ-MLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN 351
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L E + F++ L L L KP R+ KY LLK+L R+ E
Sbjct: 352 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHME 403
>BC045552-1|AAH45552.1| 471|Homo sapiens FGD4 protein protein.
Length = 471
Score = 47.6 bits (108), Expect = 2e-04
Identities = 49/271 (18%), Positives = 117/271 (43%), Gaps = 16/271 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSERL 470
+F N+ + FH L +LE+ + E ++K F ++Y Y + + L
Sbjct: 5 IFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMEL 64
Query: 471 RETLVDT-----HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + + + + ++ L L ++L+PVQRI +Y++LLKD LR S+
Sbjct: 65 VKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLD 124
Query: 526 -TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ---QGELLMQGSFLVVSENK--XX 579
+++L+ + N ++ ++ +++ + + E ++ S ++ E +
Sbjct: 125 WNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKL 184
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
++FL+ +L+C P +K T + + +I T++ + F+
Sbjct: 185 AARNTSARERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYP-HTFQ 243
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
V G+ + A + + K W++ ++ +
Sbjct: 244 V--SGKERTLELQASSAQDKEEWIKALQETI 272
>AK057294-1|BAB71413.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ32732 fis, clone TESTI2001141, highly similar to
Rattus norvegicus actin-filament binding protein Frabin
mRNA. ).
Length = 766
Score = 47.6 bits (108), Expect = 2e-04
Identities = 49/271 (18%), Positives = 117/271 (43%), Gaps = 16/271 (5%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALC--FVEKRETFFRLYSYYCQNIPRSERL 470
+F N+ + FH L +LE+ + E ++K F ++Y Y + + L
Sbjct: 253 IFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMEL 312
Query: 471 RETLVDT-----HLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT 525
+ + + + + + ++ L L ++L+PVQRI +Y++LLKD LR S+
Sbjct: 313 VKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLD 372
Query: 526 -TGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQ---QGELLMQGSFLVVSENK--XX 579
+++L+ + N ++ ++ +++ + + E ++ S ++ E +
Sbjct: 373 WNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKL 432
Query: 580 XXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFE 639
++FL+ +L+C P +K T + + +I T++ + F+
Sbjct: 433 AARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYP-HTFQ 491
Query: 640 VWRQGRCEVHTITAPTVEVKRAWVERIKRVL 670
V G+ + A + + K W++ ++ +
Sbjct: 492 V--SGKERTLELQASSAQDKEEWIKALQETI 520
>BX538322-1|CAD98096.1| 1210|Homo sapiens hypothetical protein
protein.
Length = 1210
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 925 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 982
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 983 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 1042
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 1043 TQDALAVVIEVANHANDTMKQ 1063
>BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 134 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 191
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 192 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 251
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 252 TQDALAVVIEVANHANDTMKQ 272
>BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 134 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 191
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 192 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 251
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 252 TQDALAVVIEVANHANDTMKQ 272
>BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine
nucleotide exchange factor protein.
Length = 710
Score = 45.6 bits (103), Expect = 6e-04
Identities = 47/191 (24%), Positives = 95/191 (49%), Gaps = 13/191 (6%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA-LCFVEKRET--F 453
EN+ + +A +LF N+ ++ + FL +LE + +++ +C + R
Sbjct: 301 ENERIRKILHPSEAHILFSNVLDVLAVSER-FLLELEHRMEENIVISDVCDIVYRYAADH 359
Query: 454 FRLYSYYCQNIPRSERL-RETLVDTHLFLQA-CQLRLGHK---LPLAAYLLKPVQRITKY 508
F +Y Y N ER ++ L + F + QL L K LP +++L+ P QRIT+
Sbjct: 360 FSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRL 419
Query: 509 QLLLKDLLRYSECGS--MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
+LL++++L+ E S T L + +VV C N+ + +++ T + + ++ E +
Sbjct: 420 KLLVQNILKRVEERSERECTALDAHKELEMVVKAC-NEGVRKMSRTEQMISIQKKMEFKI 478
Query: 567 QGSFLVVSENK 577
+ S ++S ++
Sbjct: 479 K-SVPIISHSR 488
>AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens
cDNA FLJ46642 fis, clone TRACH3003037, weakly similar
to Rho/Rac guanine nucleotide exchange factor. ).
Length = 1053
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 548 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 605
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 606 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 665
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 666 TQDALAVVIEVANHANDTMKQ 686
>AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens cDNA
FLJ42914 fis, clone BRHIP3025161, weakly similar to
Rho/Rac guanine nucleotide exchange factor. ).
Length = 1430
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATE--LVALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 925 LPQLYELNRDL-LKELEERMLHWTEHQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 982
Query: 474 LVDTHLFLQAC--QLRLGHK---LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 983 QCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 1042
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 1043 TQDALAVVIEVANHANDTMKQ 1063
>AJ238899-1|CAC00686.1| 425|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 425
Score = 45.6 bits (103), Expect = 6e-04
Identities = 47/191 (24%), Positives = 95/191 (49%), Gaps = 13/191 (6%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA-LCFVEKRET--F 453
EN+ + +A +LF N+ ++ + FL +LE + +++ +C + R
Sbjct: 143 ENERIRKILHPSEAHILFSNVLDVLAVSER-FLLELEHRMEENIVISDVCDIVYRYAADH 201
Query: 454 FRLYSYYCQNIPRSERL-RETLVDTHLFLQA-CQLRLGHK---LPLAAYLLKPVQRITKY 508
F +Y Y N ER ++ L + F + QL L K LP +++L+ P QRIT+
Sbjct: 202 FSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRL 261
Query: 509 QLLLKDLLRYSECGS--MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
+LL++++L+ E S T L + +VV C N+ + +++ T + + ++ E +
Sbjct: 262 KLLVQNILKRVEERSERECTALDAHKELEMVVKAC-NEGVRKMSRTEQMISIQKKMEFKI 320
Query: 567 QGSFLVVSENK 577
+ S ++S ++
Sbjct: 321 K-SVPIISHSR 330
>AC016692-1|AAX93288.1| 582|Homo sapiens unknown protein.
Length = 582
Score = 45.6 bits (103), Expect = 6e-04
Identities = 47/191 (24%), Positives = 95/191 (49%), Gaps = 13/191 (6%)
Query: 397 ENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVA-LCFVEKRET--F 453
EN+ + +A +LF N+ ++ + FL +LE + +++ +C + R
Sbjct: 173 ENERIRKILHPSEAHILFSNVLDVLAVSER-FLLELEHRMEENIVISDVCDIVYRYAADH 231
Query: 454 FRLYSYYCQNIPRSERL-RETLVDTHLFLQA-CQLRLGHK---LPLAAYLLKPVQRITKY 508
F +Y Y N ER ++ L + F + QL L K LP +++L+ P QRIT+
Sbjct: 232 FSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRL 291
Query: 509 QLLLKDLLRYSECGS--MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLM 566
+LL++++L+ E S T L + +VV C N+ + +++ T + + ++ E +
Sbjct: 292 KLLVQNILKRVEERSERECTALDAHKELEMVVKAC-NEGVRKMSRTEQMISIQKKMEFKI 350
Query: 567 QGSFLVVSENK 577
+ S ++S ++
Sbjct: 351 K-SVPIISHSR 360
>AB199796-1|BAF43710.1| 675|Homo sapiens hypothetical protein
protein.
Length = 675
Score = 44.8 bits (101), Expect = 0.001
Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 14/149 (9%)
Query: 408 GQADVLFGNLHELFTFHQDVFLKDLERCISATE----LVALCFVEKRETFFRLYSYYCQN 463
G DVLF N+ ++ + FL DL+ S E LV F+E +E ++Y YC +
Sbjct: 66 GDLDVLFSNIDDIIKVNSR-FLHDLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCAS 124
Query: 464 IPRSERLRETL-----VDTHL--FLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLL 516
++ L +T + H+ ++A + G L+ L+ P+QRIT+Y LLL+ +L
Sbjct: 125 YDQALLLVDTYRKEPELQRHIQGIVEAVVPQAGSS-GLSFLLVIPLQRITRYPLLLQKIL 183
Query: 517 RYS-ECGSMTTGLQQALDCMLVVLKCVND 544
+ S LQ+A+ + V +N+
Sbjct: 184 ENTVPDASAYPVLQRAVSALQDVNTNINE 212
>AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein.
Length = 699
Score = 44.8 bits (101), Expect = 0.001
Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 11/141 (7%)
Query: 417 LHELFTFHQDVFLKDLE-RCISATEL--VALCFVEKRETFFRLYSYYCQNIPRSERLRET 473
L +L+ ++D+ LK+LE R + TE +A FV K+ + ++YS Y + ++ L +
Sbjct: 257 LPQLYELNRDL-LKELEERMLHWTEQQRIADIFV-KKGPYLKMYSTYIKEFDKNIALLDE 314
Query: 474 LVDTHLFLQAC--QLRLGH---KLPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTG 527
+ A + + L L YLLKPVQRI +Y+LLL D L+ E
Sbjct: 315 QCKKNPGFAAVVREFEMSPCCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRD 374
Query: 528 LQQALDCMLVVLKCVNDSMHQ 548
Q AL ++ V ND+M Q
Sbjct: 375 TQDALAVVIEVANHANDTMKQ 395
>BC109095-1|AAI09096.1| 790|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 6
protein.
Length = 790
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>BC105961-1|AAI05962.1| 790|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 6
protein.
Length = 790
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>BC104751-1|AAI04752.1| 790|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 6
protein.
Length = 790
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>BC104723-1|AAI04724.2| 526|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 526
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>BC098272-1|AAH98272.2| 526|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 526
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>BC098122-1|AAH98122.2| 526|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 526
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>BC068513-1|AAH68513.1| 576|Homo sapiens ARHGEF3 protein protein.
Length = 576
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 216 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 274
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 275 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 327
>BC054345-1|AAH54345.2| 526|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 526
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>AK095373-1|BAC04539.1| 758|Homo sapiens protein ( Homo sapiens
cDNA FLJ38054 fis, clone CTONG2014635. ).
Length = 758
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 173 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 232
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 233 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 291
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 292 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 324
>AK024340-1|BAB14891.1| 412|Homo sapiens protein ( Homo sapiens
cDNA FLJ14278 fis, clone PLACE1005549, weakly similar to
Homo sapiens mRNA for Rho guanine nucleotide-exchange
factor, ).
Length = 412
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 52 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 110
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 111 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 163
>AK023741-1|BAB14663.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ13679 fis, clone PLACE2000006. ).
Length = 522
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>AK001527-1|BAA91741.1| 790|Homo sapiens protein ( Homo sapiens
cDNA FLJ10665 fis, clone NT2RP2006200. ).
Length = 790
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 410 ADVLFGNLHELFTFHQDVFLKDL-----ERCISATELVALCFVEKRETF---FRLYSYYC 461
A+ LFGN+ L H+ + + L E S L + TF F Y YC
Sbjct: 205 AETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYC 264
Query: 462 ----QNIPRSERLRETLVDTHLFLQACQL--RLGHKLPLAAYLLKPVQRITKYQLLLKDL 515
Q + + +ET H F+Q C+ R G ++ L L+KP QRITKY LLL +
Sbjct: 265 LRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQM-LCDLLIKPHQRITKYPLLLHAV 323
Query: 516 LRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L+ S L ++ + L+ +N + Q
Sbjct: 324 LKRSPEARAQEALNAMIEAVESFLRHINGQVRQ 356
>AF433662-1|AAP97313.1| 558|Homo sapiens RhoGEF protein protein.
Length = 558
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 198 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 256
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 257 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 309
>AF249744-1|AAF79954.1| 526|Homo sapiens RhoGEF protein.
Length = 526
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 166 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 224
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 225 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 277
>AB209661-1|BAD92898.1| 537|Homo sapiens Rho guanine nucleotide
exchange factor 3 variant protein.
Length = 537
Score = 43.2 bits (97), Expect = 0.003
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 413 LFGNLHELFTFHQDVF--LKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERL 470
+FG L L H+++ L+D+ + +TE V V Y YC N ++ L
Sbjct: 177 IFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS-YDSYCSNQVAAKAL 235
Query: 471 RETLVDTHL---FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYS 519
+ H FLQ C + KL L +L P R+ KY LLL+++LR++
Sbjct: 236 LDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT 288
>D89016-1|BAA13745.1| 421|Homo sapiens Neuroblastoma protein.
Length = 421
Score = 42.7 bits (96), Expect = 0.005
Identities = 47/203 (23%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E +F Y YC N +R
Sbjct: 40 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKYFHPYIAYCSNEVYQQR 98
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 99 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 158
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 159 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 212
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 213 WLLKRGELFLVEETGLFRKIASR 235
>BT007270-1|AAP35934.1| 421|Homo sapiens Rho guanine exchange
factor (GEF) 16 protein.
Length = 421
Score = 42.7 bits (96), Expect = 0.005
Identities = 47/203 (23%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E +F Y YC N +R
Sbjct: 40 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKYFHPYIAYCSNEVYQQR 98
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 99 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 158
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 159 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 212
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 213 WLLKRGELFLVEETGLFRKIASR 235
>BC053616-1|AAH53616.1| 1483|Homo sapiens PREX1 protein protein.
Length = 1483
Score = 42.7 bits (96), Expect = 0.005
Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMT-TGLQQALDCMLVVLKCVNDSMHQI 549
+PL YLL P+QRI KY LLLK+L + + +Q AL M V +N++ Q+
Sbjct: 10 IPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQM 68
>BC040640-1|AAH40640.1| 802|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 802
Score = 42.7 bits (96), Expect = 0.005
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 420 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 478
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 479 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 538
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 539 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 576
>BC012982-1|AAH12982.1| 706|Homo sapiens ARHGEF19 protein protein.
Length = 706
Score = 42.7 bits (96), Expect = 0.005
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 324 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 382
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 383 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 442
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 443 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 480
>BC002681-1|AAH02681.1| 421|Homo sapiens Rho guanine exchange
factor (GEF) 16 protein.
Length = 421
Score = 42.7 bits (96), Expect = 0.005
Identities = 47/203 (23%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E +F Y YC N +R
Sbjct: 40 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKYFHPYIAYCSNEVYQQR 98
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 99 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 158
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 159 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 212
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 213 WLLKRGELFLVEETGLFRKIASR 235
>AL109627-10|CAI22568.1| 306|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 306
Score = 42.7 bits (96), Expect = 0.005
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 108 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 166
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 167 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 226
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 227 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 264
>AL109627-9|CAI22566.1| 802|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 802
Score = 42.7 bits (96), Expect = 0.005
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 10/158 (6%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATEL-VALCFV--EKRETFFRLYSYYCQNIPRSER 469
LF L E+ + + FL+DLE+ + A L ++C V + F R+Y Y N ER
Sbjct: 420 LFSKLPEVKSTSER-FLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQER 478
Query: 470 LRETLVDTHLFLQACQLRLGH-----KLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSM 524
+ L+ + RL +LPL ++L+ P QRIT+ ++L++++L+ + GS
Sbjct: 479 TYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSE 538
Query: 525 TTGL-QQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQ 561
+ +A + + +++ N S+ + T + LS++
Sbjct: 539 DEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKK 576
>BC051838-1|AAH51838.1| 421|Homo sapiens ARHGEF16 protein protein.
Length = 421
Score = 41.1 bits (92), Expect = 0.014
Identities = 47/203 (23%), Positives = 83/203 (40%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E F Y YC N +R
Sbjct: 40 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQR 98
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 99 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 158
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 159 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 212
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 213 WLLKRGELFLVEETGLFRKIASR 235
>AL512413-2|CAH70833.1| 421|Homo sapiens Rho guanine exchange
factor (GEF) 16 protein.
Length = 421
Score = 41.1 bits (92), Expect = 0.014
Identities = 47/203 (23%), Positives = 83/203 (40%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E F Y YC N +R
Sbjct: 40 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQR 98
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 99 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 158
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 159 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 212
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 213 WLLKRGELFLVEETGLFRKIASR 235
>AL512413-1|CAH70832.1| 709|Homo sapiens Rho guanine exchange
factor (GEF) 16 protein.
Length = 709
Score = 41.1 bits (92), Expect = 0.014
Identities = 47/203 (23%), Positives = 83/203 (40%), Gaps = 16/203 (7%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELV---ALCFVEKRETFFRLYSYYCQNIPRSER 469
LF N+ ++ Q F +DLE+ A LV + E E F Y YC N +R
Sbjct: 328 LFSNILDVLGASQR-FFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQR 386
Query: 470 LRETLVDTHLFLQACQLRLGHK-----LPLAAYLLKPVQRITKYQLLLKDL-LRYSECGS 523
+ L+ ++ + + + LP+ ++L+ P+QR+T+ LL+ L L+
Sbjct: 387 TLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSE 446
Query: 524 MTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXXXX 583
+AL + +++ N+ H++ + Q L Q F V
Sbjct: 447 RYKAASRALKAISKLVRQCNEGAHRME------RMEQMYTLHTQLDFSKVKSLPLISASR 500
Query: 584 XXXXXXHIFLYEKAMLFCKPATK 606
+FL E+ LF K A++
Sbjct: 501 WLLKRGELFLVEETGLFRKIASR 523
>AK002045-1|BAA92052.1| 432|Homo sapiens protein ( Homo sapiens
cDNA FLJ11183 fis, clone PLACE1007488, weakly similar to
PUTATIVE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR. ).
Length = 432
Score = 41.1 bits (92), Expect = 0.014
Identities = 26/58 (44%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L L YLLKPVQRI +Y+LLL D L+ E Q AL ++ V ND+M Q
Sbjct: 8 LALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQ 65
>BC013319-1|AAH13319.1| 376|Homo sapiens FGD6 protein protein.
Length = 376
Score = 40.7 bits (91), Expect = 0.018
Identities = 26/58 (44%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLR-YSECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
L L YLLKPVQRI +Y+LLL D L+ E Q AL ++ V ND+M Q
Sbjct: 8 LALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVVEVANHANDTMKQ 65
>D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein.
Length = 773
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 282 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 340
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 341 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 392
>BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein.
Length = 538
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 131 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 189
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 190 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 241
>BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 285 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 343
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 344 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 395
>AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein.
Length = 1577
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 827 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 881
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 882 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 937
>AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 285 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 343
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 344 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 395
>AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 827 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 881
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 882 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 937
>AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 827 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 881
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 882 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 937
>AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 827 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 881
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 882 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 937
>AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 622
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 131 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 189
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 190 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 241
>AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 40.3 bits (90), Expect = 0.024
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATE---LVALCFVEKRETFFRLYSYYCQNIPRSER 469
L GN E+ TF Q + + LE C E V C + F +Y YC N P +
Sbjct: 285 LLGNFEEVCTFQQTL-CQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVN 343
Query: 470 -LRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSE 520
L + + F++ L L L KP R+ KY LL++L R+ E
Sbjct: 344 VLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHME 395
>AB023227-1|BAA76854.1| 1315|Homo sapiens KIAA1010 protein protein.
Length = 1315
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 565 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 619
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 620 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 675
>U02081-1|AAB08847.1| 460|Homo sapiens guanine nucleotide
regulatory protein protein.
Length = 460
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 76 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 134
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 135 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 194
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 195 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 251
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 252 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 305
>BC053553-1|AAH53553.1| 596|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 596
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 218 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 276
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 277 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 336
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 337 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 393
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 394 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 447
>BC041628-1|AAH41628.1| 823|Homo sapiens DNMBP protein protein.
Length = 823
Score = 39.9 bits (89), Expect = 0.032
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 430 KDLERCISATELVALCFVEKRETFFRLYSYYCQN----------IPRSERLRETLVDTHL 479
K L + ++ V F+ R+ Y YCQN + E++++ L D+
Sbjct: 85 KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLA 144
Query: 480 FLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDLL 516
L++ G + + L ++L+KPVQR+ +Y LLL +LL
Sbjct: 145 DLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELL 183
>BC010285-1|AAH10285.1| 542|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 542
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 164 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 222
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 223 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 282
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 283 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 339
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 340 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 393
>AL732437-5|CAI11033.1| 596|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 596
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 218 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 276
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 277 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 336
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 337 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 393
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 394 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 447
>AL732437-3|CAI11031.1| 542|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 542
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 164 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 222
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 223 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 282
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 283 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 339
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 340 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 393
>AJ010046-1|CAA08974.1| 548|Homo sapiens guanine
nucleotide-exchange factor protein.
Length = 548
Score = 39.9 bits (89), Expect = 0.032
Identities = 50/235 (21%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 413 LFGNLHELFTFHQDVFLK--DLERCISATELVALCFVEKRETFFRLYSYYCQN-IPRSER 469
+FG+L H+D+ + + + E + V Y YC N +
Sbjct: 164 IFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRL-NAYRGYCSNQLAAKAL 222
Query: 470 LRETLVDTHL--FLQAC-QLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTT 526
L + D + FLQ C + KL L ++L P R+ KY LLLK++L+++
Sbjct: 223 LDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDV 282
Query: 527 G-LQQALDCMLVVLKCVN----DSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKXXXX 581
L+ A+ + VL +N +S Q I + +Q + ++ S +++ +
Sbjct: 283 QLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGE---L 339
Query: 582 XXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLR 636
+IFL++ ++ +P T+N + ++ + + ++ L + GD+R
Sbjct: 340 RSKSGHKLYIFLFQDILVLTRPVTRNERHSYQV-YRQPIPVQELVLEDLQDGDVR 393
>AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein.
Length = 1113
Score = 39.5 bits (88), Expect = 0.043
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 17/117 (14%)
Query: 557 DLSQQGELLMQGSFLVVSENKXXXXXXXXXXXXHIFLYEKAMLFCKPATKNSHNKATYHF 616
DL+ GEL+++G+F + +FL++K +L K T+ +
Sbjct: 45 DLTSYGELVLEGTFRIQRAKNERT----------LFLFDKLLLITKKRDD------TFTY 88
Query: 617 KHDLLMSQIGLTESVKGDLRKFEVWRQGRCEV-HTITAPTVEVKRAWVERIKRVLLD 672
K +L + L E + + F V+ ++ HT+ A + + KR WV +KR++L+
Sbjct: 89 KAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILE 145
>AK000302-1|BAA91068.1| 436|Homo sapiens protein ( Homo sapiens
cDNA FLJ20295 fis, clone HEP05888. ).
Length = 436
Score = 39.1 bits (87), Expect = 0.056
Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+PL+++LLKP+QRIT+Y LL++ +L + E + + L+ AL+ + VN+ + +
Sbjct: 80 MPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVRE 137
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 39.1 bits (87), Expect = 0.056
Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+PL+++LLKP+QRIT+Y LL++ +L + E + + L+ AL+ + VN+ + +
Sbjct: 1325 MPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVRE 1382
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 39.1 bits (87), Expect = 0.056
Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+PL+++LLKP+QRIT+Y LL++ +L + E + + L+ AL+ + VN+ + +
Sbjct: 1340 MPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVRE 1397
>AC008073-6|AAY14668.1| 367|Homo sapiens unknown protein.
Length = 367
Score = 39.1 bits (87), Expect = 0.056
Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+PL+++LLKP+QRIT+Y LL++ +L + E + + L+ AL+ + VN+ + +
Sbjct: 11 MPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVRE 68
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 39.1 bits (87), Expect = 0.056
Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 492 LPLAAYLLKPVQRITKYQLLLKDLLRYS-ECGSMTTGLQQALDCMLVVLKCVNDSMHQ 548
+PL+++LLKP+QRIT+Y LL++ +L + E + + L+ AL+ + VN+ + +
Sbjct: 1320 MPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVRE 1377
>AL627434-1|CAI13196.1| 224|Homo sapiens novel protein protein.
Length = 224
Score = 38.7 bits (86), Expect = 0.074
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 17/115 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 115 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 169
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDL 515
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +L
Sbjct: 170 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMEL 224
>AL392107-1|CAI11008.1| 224|Homo sapiens novel protein protein.
Length = 224
Score = 38.7 bits (86), Expect = 0.074
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 17/115 (14%)
Query: 413 LFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQN--------- 463
LFGN+ + K L + ++ V F+ R+ Y YCQN
Sbjct: 115 LFGNMQMVIKVS-----KQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLE 169
Query: 464 -IPRSERLRETLVDTHLFLQACQLRLG--HKLPLAAYLLKPVQRITKYQLLLKDL 515
+ E++++ L D+ L++ G + + L ++L+KPVQR+ +Y LLL +L
Sbjct: 170 IYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMEL 224
>BC042606-1|AAH42606.1| 1043|Homo sapiens PLEKHG5 protein protein.
Length = 1043
Score = 38.3 bits (85), Expect = 0.098
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCIS-ATELVALC----FVEKRETF---FRLYSYY 460
+A+ LF N+ E+ H+ ++ + + A AL F++ + F F+ Y Y
Sbjct: 416 EAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRY 475
Query: 461 CQNIPRS-ERLRETLVDTHLFLQACQLRLGH----KLPLAAYLLKPVQRITKYQLLLKDL 515
C E +R L D LF H +L L+ L KP QR+TKY LLLK +
Sbjct: 476 CMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSV 535
Query: 516 LRYSE 520
LR +E
Sbjct: 536 LRKTE 540
>BC015231-1|AAH15231.1| 930|Homo sapiens PLEKHG5 protein protein.
Length = 930
Score = 38.3 bits (85), Expect = 0.098
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCIS-ATELVALC----FVEKRETF---FRLYSYY 460
+A+ LF N+ E+ H+ ++ + + A AL F++ + F F+ Y Y
Sbjct: 379 EAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRY 438
Query: 461 CQNIPRS-ERLRETLVDTHLFLQACQLRLGH----KLPLAAYLLKPVQRITKYQLLLKDL 515
C E +R L D LF H +L L+ L KP QR+TKY LLLK +
Sbjct: 439 CMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSV 498
Query: 516 LRYSE 520
LR +E
Sbjct: 499 LRKTE 503
>AL591866-2|CAI16068.1| 852|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 5
protein.
Length = 852
Score = 38.3 bits (85), Expect = 0.098
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 409 QADVLFGNLHELFTFHQDVFLKDLERCIS-ATELVALC----FVEKRETF---FRLYSYY 460
+A+ LF N+ E+ H+ ++ + + A AL F++ + F F+ Y Y
Sbjct: 456 EAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRY 515
Query: 461 CQNIPRS-ERLRETLVDTHLFLQACQLRLGH----KLPLAAYLLKPVQRITKYQLLLKDL 515
C E +R L D LF H +L L+ L KP QR+TKY LLLK +
Sbjct: 516 CMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSV 575
Query: 516 LRYSE 520
LR +E
Sbjct: 576 LRKTE 580
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.132 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,161,151
Number of Sequences: 224733
Number of extensions: 4126090
Number of successful extensions: 8960
Number of sequences better than 10.0: 326
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 99
Number of HSP's that attempted gapping in prelim test: 8277
Number of HSP's gapped (non-prelim): 418
length of query: 749
length of database: 73,234,838
effective HSP length: 96
effective length of query: 653
effective length of database: 51,660,470
effective search space: 33734286910
effective search space used: 33734286910
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)
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