Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002678-TA|BGIBMGA002678-PA|IPR006020|Phosphotyrosine
interaction region, IPR000980|SH2 motif
(418 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 293 4e-78
UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37... 215 2e-54
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 200 5e-50
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 200 5e-50
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 197 4e-49
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 193 6e-48
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 187 4e-46
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 184 3e-45
UniRef50_Q3ZAX3 Cluster: Shc3 protein; n=4; Euteleostomi|Rep: Sh... 184 4e-45
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 182 2e-44
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 145 2e-33
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 138 3e-31
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 126 8e-28
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 116 1e-24
UniRef50_A3KNZ1 Cluster: Zgc:162768 protein; n=6; Euteleostomi|R... 79 2e-13
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 77 1e-12
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 67 9e-10
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 64 9e-09
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 62 2e-08
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 62 3e-08
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 61 5e-08
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 60 1e-07
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 60 1e-07
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 59 2e-07
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 59 2e-07
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 58 4e-07
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 58 6e-07
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 58 6e-07
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 57 7e-07
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 57 7e-07
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 56 2e-06
UniRef50_O76337 Cluster: Cell death protein 6; n=2; Caenorhabdit... 56 2e-06
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 56 2e-06
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 56 2e-06
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 56 2e-06
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 55 3e-06
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 55 3e-06
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 55 3e-06
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 55 3e-06
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 54 5e-06
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 54 5e-06
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 54 5e-06
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 54 7e-06
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 54 9e-06
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 53 2e-05
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 53 2e-05
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 53 2e-05
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 53 2e-05
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 52 3e-05
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 52 3e-05
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 52 3e-05
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 52 3e-05
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 52 3e-05
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 52 4e-05
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 52 4e-05
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 52 4e-05
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 51 5e-05
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 51 5e-05
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 51 5e-05
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 51 7e-05
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 51 7e-05
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 50 9e-05
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 50 1e-04
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 50 2e-04
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 50 2e-04
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 50 2e-04
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 49 2e-04
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 49 2e-04
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 49 3e-04
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 49 3e-04
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 49 3e-04
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 48 3e-04
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 48 3e-04
UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 48 5e-04
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 48 5e-04
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 48 5e-04
UniRef50_UPI0000F2C9D9 Cluster: PREDICTED: similar to SHC-transf... 48 6e-04
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 48 6e-04
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 48 6e-04
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 47 8e-04
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 47 8e-04
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 47 0.001
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 47 0.001
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 47 0.001
UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ... 46 0.001
UniRef50_UPI000051A3DF Cluster: PREDICTED: similar to ced-6 CG11... 46 0.001
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 46 0.002
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 46 0.002
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 46 0.002
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 45 0.003
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 45 0.003
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 45 0.003
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 45 0.003
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 45 0.004
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 45 0.004
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 44 0.006
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.006
UniRef50_UPI0000E25482 Cluster: PREDICTED: hypothetical protein;... 44 0.007
UniRef50_UPI00003AFA59 Cluster: PREDICTED: Gallus gallus similar... 44 0.007
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 44 0.007
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 44 0.007
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 44 0.007
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 44 0.007
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 44 0.010
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 44 0.010
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 44 0.010
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 44 0.010
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 44 0.010
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 44 0.010
UniRef50_A7RZG4 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.010
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 44 0.010
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 43 0.013
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 43 0.017
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 43 0.017
UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma j... 43 0.017
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 43 0.017
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.017
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 43 0.017
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 42 0.023
UniRef50_Q8NFT0 Cluster: Src homology 2 domain-containing transf... 42 0.023
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 42 0.023
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 42 0.023
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 42 0.023
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 42 0.023
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 42 0.023
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 42 0.030
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 42 0.030
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 42 0.030
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 42 0.030
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 42 0.030
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 42 0.030
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 42 0.030
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 42 0.030
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 42 0.030
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 42 0.030
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 42 0.030
UniRef50_UPI0000D56ADB Cluster: PREDICTED: similar to CG11804-PC... 42 0.040
UniRef50_Q9VC09 Cluster: CG11168-PA; n=3; Sophophora|Rep: CG1116... 42 0.040
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 42 0.040
UniRef50_UPI000065D045 Cluster: cajalin 2 isoform a; n=1; Takifu... 41 0.053
UniRef50_Q4RGC9 Cluster: Chromosome 19 SCAF15103, whole genome s... 41 0.053
UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1; ... 41 0.053
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 41 0.053
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 41 0.070
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 41 0.070
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 41 0.070
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 41 0.070
UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s... 40 0.092
UniRef50_Q9VCM6 Cluster: CG4393-PA; n=3; Sophophora|Rep: CG4393-... 40 0.092
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 40 0.092
UniRef50_UPI0000F2C764 Cluster: PREDICTED: similar to SH2-contai... 40 0.12
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 40 0.12
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 40 0.12
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 40 0.12
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 40 0.12
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 40 0.12
UniRef50_Q99767 Cluster: Amyloid beta A4 precursor protein-bindi... 40 0.12
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 40 0.16
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 40 0.16
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 40 0.16
UniRef50_Q4S5P0 Cluster: Chromosome 9 SCAF14729, whole genome sh... 40 0.16
UniRef50_Q8TAP3 Cluster: Ankyrin repeat and sterile alpha motif ... 40 0.16
UniRef50_Q7Z6G8 Cluster: Ankyrin repeat and sterile alpha motif ... 40 0.16
UniRef50_Q7Z6G6 Cluster: AIDA-1bDAnk; n=15; Euarchontoglires|Rep... 40 0.16
UniRef50_A7E259 Cluster: ANKS1B protein; n=7; Eutheria|Rep: ANKS... 40 0.16
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 40 0.16
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 39 0.21
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 39 0.21
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 39 0.21
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 39 0.21
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 39 0.21
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 39 0.21
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 39 0.21
UniRef50_A7RG70 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 39 0.21
UniRef50_Q5RGM2 Cluster: Novel protein containing a phosphotyros... 39 0.28
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 39 0.28
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 39 0.28
UniRef50_UPI00015B6225 Cluster: PREDICTED: similar to IP14385p; ... 38 0.37
UniRef50_UPI000065E21B Cluster: Homolog of Homo sapiens "ankyrin... 38 0.37
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 38 0.37
UniRef50_Q7JUY7 Cluster: PTB domain-containing adapter protein c... 38 0.37
UniRef50_UPI0000E8216F Cluster: PREDICTED: similar to LPAL6438, ... 38 0.49
UniRef50_UPI0000D55DD1 Cluster: PREDICTED: similar to CG4393-PA;... 38 0.49
UniRef50_Q6IRM7 Cluster: MGC83933 protein; n=5; Tetrapoda|Rep: M... 38 0.49
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 38 0.49
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 38 0.49
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 38 0.49
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 38 0.65
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 38 0.65
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 38 0.65
UniRef50_A4TUR6 Cluster: Methyl-accepting chemotaxis protein; n=... 38 0.65
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 38 0.65
UniRef50_Q92625 Cluster: Ankyrin repeat and SAM domain-containin... 38 0.65
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 37 0.86
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 37 0.86
UniRef50_A3AC81 Cluster: Putative uncharacterized protein; n=3; ... 37 0.86
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 37 0.86
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 37 0.86
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 37 0.86
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 37 1.1
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 37 1.1
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 37 1.1
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 37 1.1
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 37 1.1
UniRef50_UPI0000F21B0F Cluster: PREDICTED: similar to Methylenet... 36 1.5
UniRef50_UPI0000D57403 Cluster: PREDICTED: similar to C-terminal... 36 1.5
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 36 1.5
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 36 2.0
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 36 2.0
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 36 2.0
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 36 2.0
UniRef50_Q0PNF0 Cluster: Gulp-2; n=14; Amniota|Rep: Gulp-2 - Mus... 36 2.0
UniRef50_Q026T3 Cluster: AAA ATPase precursor; n=1; Solibacter u... 36 2.0
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 36 2.0
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 36 2.0
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 36 2.0
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 36 2.0
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 36 2.0
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 36 2.0
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 36 2.6
UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,... 36 2.6
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;... 36 2.6
UniRef50_O84156 Cluster: Phospholipase D Endonuclease Superfamil... 36 2.6
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 36 2.6
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 36 2.6
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 36 2.6
UniRef50_Q9UBP9 Cluster: PTB domain-containing engulfment adapte... 36 2.6
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 36 2.6
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 35 3.5
UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin... 35 3.5
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 35 3.5
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 35 3.5
UniRef50_Q21429 Cluster: Putative uncharacterized protein; n=1; ... 35 3.5
UniRef50_A1CSQ5 Cluster: Acetyltransferase, CysE/LacA/LpxA/NodL ... 35 3.5
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 35 3.5
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 35 4.6
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 35 4.6
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 35 4.6
UniRef50_Q3JWB4 Cluster: Putative uncharacterized protein; n=7; ... 35 4.6
UniRef50_Q9XXE5 Cluster: Putative uncharacterized protein; n=1; ... 35 4.6
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 35 4.6
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 35 4.6
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 34 6.0
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 34 6.0
UniRef50_Q4QCT8 Cluster: Putative uncharacterized protein; n=2; ... 34 6.0
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 34 6.0
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 34 6.0
UniRef50_Q8STF6 Cluster: Dystrophin-like protein 1; n=6; Bilater... 34 6.0
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 34 8.0
UniRef50_UPI0000F1D550 Cluster: PREDICTED: similar to carboxyl-t... 34 8.0
UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain... 34 8.0
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 34 8.0
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 34 8.0
UniRef50_Q0FVV8 Cluster: VCBS; n=3; cellular organisms|Rep: VCBS... 34 8.0
UniRef50_A5DLL7 Cluster: Putative uncharacterized protein; n=1; ... 34 8.0
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 34 8.0
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 34 8.0
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 293 bits (720), Expect = 4e-78
Identities = 142/225 (63%), Positives = 176/225 (78%), Gaps = 14/225 (6%)
Query: 1 MAESGS-FVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECI 59
MA GS F++KPARGWLHPD +++ +G+TY V+YIGC+EV TSMK LDF+TRS VAKECI
Sbjct: 1 MATGGSSFISKPARGWLHPDHLVSKEGITYTVKYIGCLEVYTSMKSLDFETRSCVAKECI 60
Query: 60 ARVCAAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIA 119
RVC AAGL+SADKKRRV + RA+ +PRM H+GA + LT+SS ++ L +E G IA
Sbjct: 61 NRVCEAAGLKSADKKRRVDRKVLRAIADKPRMEHTGATINLTISSCSLALTNIENGHIIA 120
Query: 120 RHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELR 179
+H+MPR+SFASGGD + LD+VAYVAK+ EWRACYVLECGG LAQDVI+TIGQAFELR
Sbjct: 121 KHEMPRISFASGGDTEILDFVAYVAKNM--QEWRACYVLECGGGLAQDVISTIGQAFELR 178
Query: 180 FKEFLTKPSTLN--LNGSLPSCESACGLVEDREYYNDMPDKVPPE 222
FKEFLTKP++L+ LNG + DR+YYND+P KVPP+
Sbjct: 179 FKEFLTKPASLHPILNGIREA---------DRDYYNDLPGKVPPD 214
Score = 138 bits (335), Expect = 2e-31
Identities = 70/143 (48%), Positives = 88/143 (61%), Gaps = 15/143 (10%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKEPWFHGPISRTTAEKL 335
D+FDMQPF + L+ +Q L +E WFHG +SR AE +
Sbjct: 315 DVFDMQPFSSAIS---------------DMNKLSPHSQKQQLKQEIWFHGSVSRAEAESM 359
Query: 336 VVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCS 395
+ DG+FLVRES GQ+VLTG KHLLL+DP GVVRTKDRVFDSV HL+ +HC
Sbjct: 360 LTRDGDFLVRESQGSPGQYVLTGMNNNTPKHLLLIDPEGVVRTKDRVFDSVSHLVNHHCD 419
Query: 396 NELPIVSADSALLLRKPVLRSSS 418
N LPI+SADS L+LR P+ R ++
Sbjct: 420 NVLPIISADSVLVLRYPIPRRTN 442
>UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep:
CG3715-PA - Drosophila melanogaster (Fruit fly)
Length = 409
Score = 215 bits (525), Expect = 2e-54
Identities = 109/212 (51%), Positives = 148/212 (69%), Gaps = 18/212 (8%)
Query: 14 GWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSADK 73
G ++PD V+ GV + VRY GC+EV TSMK LDF+TR+Q+A+ECI RVC AAGL+SA K
Sbjct: 19 GCIYPDDVIMGVGVAFNVRYTGCVEVKTSMKSLDFETRTQLARECINRVCEAAGLKSAGK 78
Query: 74 KRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGD 133
+R ++ RP M H+G N+ + VSS+A++L+ +E G+ IA H+MPR+SFASGGD
Sbjct: 79 RR-----LTNFISDRPSMQHAGTNIIINVSSRALSLSNVETGEVIANHNMPRISFASGGD 133
Query: 134 ADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF--LTKPST-L 190
D+LD++AY+AK+ EWRACYVLEC G ++D+I TIG+AF LRF L PS
Sbjct: 134 NDTLDFLAYIAKN--EDEWRACYVLECAGGQSEDLIVTIGKAFALRFNALSRLNDPSADC 191
Query: 191 NLNGSLPSCESACGLVEDREYYNDMPDKVPPE 222
N+N SC+ +EYYND+P+K+PPE
Sbjct: 192 NIN---QSCKE-----NVKEYYNDLPNKLPPE 215
Score = 125 bits (302), Expect = 2e-27
Identities = 59/99 (59%), Positives = 72/99 (72%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L E WFH ISR +E+L+ +DG+FLVRES GQ+VLTG KHLLL+DP GVV
Sbjct: 296 LTAEVWFHAGISRPISERLLQQDGDFLVRESQGKRGQYVLTGLEGKTPKHLLLIDPEGVV 355
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKDR+FDS+ HLI YH ++ LPI+S DS L+LR PV R
Sbjct: 356 RTKDRIFDSISHLINYHWAHALPIISEDSELVLRNPVRR 394
>UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c); n=8;
Theria|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c) -
Homo sapiens (Human)
Length = 473
Score = 200 bits (488), Expect = 5e-50
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 147
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 148 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 205
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 206 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 249
Score = 128 bits (310), Expect = 2e-28
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 363 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 422
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 423 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 471
>UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46;
Tetrapoda|Rep: SHC-transforming protein 1 - Homo sapiens
(Human)
Length = 583
Score = 200 bits (488), Expect = 5e-50
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 197
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 198 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 257
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 258 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 315
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 316 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 359
Score = 128 bits (310), Expect = 2e-28
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 473 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 532
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 533 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 581
>UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15;
Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens
(Human)
Length = 551
Score = 197 bits (481), Expect = 4e-49
Identities = 105/223 (47%), Positives = 144/223 (64%), Gaps = 9/223 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSF+ KPA GWLHPD+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I R+
Sbjct: 98 GSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHE 157
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G+R + KK+ ++A A L + + +G ++++ +S+ ++L+V IA H M
Sbjct: 158 AVPGVRGSWKKKAPNKALASVL-GKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHM 216
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
P +SFASGGD D DYVAYVAK P RAC++LEC LAQ +I+T+GQAFELRFK++
Sbjct: 217 PSISFASGGDTDMTDYVAYVAKD--PINQRACHILECCEGLAQSIISTVGQAFELRFKQY 274
Query: 184 LTKPSTLNLNGSLPSC--ESACGLVED---REYYNDMPDKVPP 221
L P + L + ESA G ED YYN +P K PP
Sbjct: 275 LHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPP 317
Score = 116 bits (279), Expect = 1e-24
Identities = 56/99 (56%), Positives = 71/99 (71%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L +EPW+HG +SR AE+++ DG+FLVR+S GQ+VLTG G KHLLLVDP GVV
Sbjct: 451 LRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV 510
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD +F+S+ HLI +H N PIV+A+S L LR V R
Sbjct: 511 RTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSR 549
>UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 480
Score = 193 bits (471), Expect = 6e-48
Identities = 91/187 (48%), Positives = 127/187 (67%), Gaps = 3/187 (1%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLH DSV+++ GV+Y VRY+GC+EVL SM+ LDF TR+QV +E I+ VC
Sbjct: 169 GSFVNKPTRGWLHSDSVVSTTGVSYTVRYMGCVEVLQSMRALDFSTRTQVTREAISVVCE 228
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ S ++ + + +G ++LT+S+ ++ L + IA H M
Sbjct: 229 AVPGAKGAQRRRKPSSRCLSSILGKSNLQFAGMTISLTISTSSLNLLACDCKQIIANHHM 288
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD ++ +YVAYVAK P RAC++LEC AQ+VI+TIGQAFELRFK++
Sbjct: 289 QSISFASGGDPETAEYVAYVAKD--PVNQRACHILECSEGFAQEVISTIGQAFELRFKQY 346
Query: 184 LTKPSTL 190
L P L
Sbjct: 347 LKNPPKL 353
Score = 124 bits (299), Expect = 4e-27
Identities = 59/96 (61%), Positives = 70/96 (72%)
Query: 320 EPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTK 379
E WFHG +SR AE+L+ DG+FLVRES GQ+VLTG + G KHLLLVDP GVVRTK
Sbjct: 383 EAWFHGGLSRKEAERLLTRDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTK 442
Query: 380 DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
D F+SV HLI YH N LPI+SA S + L++PV R
Sbjct: 443 DHRFESVSHLISYHMDNRLPIISAGSEVCLKQPVER 478
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 187 bits (456), Expect = 4e-46
Identities = 97/234 (41%), Positives = 143/234 (61%), Gaps = 17/234 (7%)
Query: 3 ESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARV 62
+ GSF+ KP++GWLHPD ++S G +Y VRY+GC+EVL SM+ LDF TR+QV +E I R+
Sbjct: 18 QKGSFINKPSQGWLHPDKKISSTGASYIVRYMGCIEVLKSMRSLDFSTRTQVTREAINRL 77
Query: 63 CAAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHD 122
C + K++ + +++ + + +G ++ + +S ++L V IA H
Sbjct: 78 CESVPGGKTAWKKKTTNKTLQSIMGKSNLRFAGMSIGVNISIDGLSLLVPTTRQVIAHHP 137
Query: 123 MPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKE 182
M +SFASGGD+D+ DYVAYVAK P RAC++LEC LAQ+VI+TIGQAFEL+FK+
Sbjct: 138 MQSISFASGGDSDTPDYVAYVAKD--PVNQRACHILECCDGLAQNVISTIGQAFELQFKQ 195
Query: 183 FLTKP----STLNLNGSLPSC--------ESACGLVE---DREYYNDMPDKVPP 221
+L P ++ + P+ ESA G E + +YYN +P K PP
Sbjct: 196 YLHSPPKAIPAMDSHAEYPNILSRNIRTEESAWGEDEESSEHDYYNSIPGKEPP 249
Score = 122 bits (294), Expect = 2e-26
Identities = 58/99 (58%), Positives = 75/99 (75%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L +E W+HG +SR AE L+ DG+FLVR+S GQ+VLTG + GL KHLLLVDP GVV
Sbjct: 401 LRREMWYHGRMSRRDAENLLGRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLLVDPEGVV 460
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD +F+S+ HLI YH +N+LPIV+A+S L L++ V R
Sbjct: 461 RTKDMLFESISHLINYHLTNKLPIVAAESELHLQQVVCR 499
>UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34;
Euteleostomi|Rep: SHC-transforming protein 3 - Homo
sapiens (Human)
Length = 594
Score = 184 bits (449), Expect = 3e-45
Identities = 95/218 (43%), Positives = 134/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 136 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 195
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 196 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 255
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 256 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 313
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 314 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 351
Score = 124 bits (300), Expect = 3e-27
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 449 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 508
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G +RTKDRVFDS+ HLI
Sbjct: 509 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLIN 568
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 569 HHLESSLPIVSAGSELCLQQPVER 592
>UniRef50_Q3ZAX3 Cluster: Shc3 protein; n=4; Euteleostomi|Rep: Shc3
protein - Mus musculus (Mouse)
Length = 341
Score = 184 bits (448), Expect = 4e-45
Identities = 97/218 (44%), Positives = 133/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+QV +E I+RVC A G
Sbjct: 16 RPPRGAPHTSDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQVTREAISRVCEAVPGA 75
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 76 KGALKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 135
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L PS
Sbjct: 136 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPS 193
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L + S + G D YYN +P K+PP
Sbjct: 194 KVPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPTKMPP 231
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 182 bits (442), Expect = 2e-44
Identities = 88/185 (47%), Positives = 118/185 (63%), Gaps = 3/185 (1%)
Query: 3 ESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARV 62
++GSF+ KP RGWLH + L GV YAV+Y+GC+ V SM+ L ++ R QV +E I R
Sbjct: 16 KTGSFLHKPDRGWLHSEGSLREGGVCYAVKYVGCLSVEKSMRTLPYEVRQQVTREAILRC 75
Query: 63 CAAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHD 122
C AAG K+++ + +R L P M+HSG NV LT+S+ + + + G IA HD
Sbjct: 76 CEAAGY-PLPKRKKPHKNVSRILGETPNMNHSGTNVNLTISATGMKMVDMNNGRRIANHD 134
Query: 123 MPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKE 182
M +SFASGG+ D ++ V YVAK RAC+V +CGG LA DVI T+GQAFE+RFK
Sbjct: 135 MQGISFASGGEKDCVNMVGYVAKD--EVNGRACHVCDCGGELAYDVINTVGQAFEIRFKM 192
Query: 183 FLTKP 187
FL P
Sbjct: 193 FLQNP 197
Score = 116 bits (278), Expect = 2e-24
Identities = 52/110 (47%), Positives = 79/110 (71%)
Query: 306 APLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHK 365
AP+ + ++ + + W+HGPISR AE L+ ++G+FLVRES + GQ+VL+G + +
Sbjct: 363 APVASTRSSSFMRAKDWYHGPISRGEAELLLEDEGDFLVRESKSQPGQYVLSGIKDKQAR 422
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
HLLLVDP G VRT+D+VF++V LI +H N++PI+SA S + ++ PVLR
Sbjct: 423 HLLLVDPQGQVRTRDKVFENVDQLISFHLVNQVPIISAGSEVTIKHPVLR 472
>UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2
domain protein C1) (Src homology 2
domain-containing-transforming protein C1).; n=2;
Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain
protein C1) (Src homology 2
domain-containing-transforming protein C1). - Takifugu
rubripes
Length = 526
Score = 145 bits (351), Expect = 2e-33
Identities = 67/142 (47%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLH D V+++ GV+Y VRY+GC+EVL SM+ LDF TR+QV +E IA VC
Sbjct: 22 GSFVNKPTRGWLHSDGVVSTSGVSYTVRYMGCVEVLQSMRALDFSTRTQVTREAIAVVCE 81
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ S ++ + + +G ++LTVS+ ++ L + IA H M
Sbjct: 82 AVPGAKGAQRRRKPSSRCLSSILGKSNLQFAGMTISLTVSTSSLNLLACDCKQIIANHHM 141
Query: 124 PRVSFASGGDADSLDYVAYVAK 145
+SFASGGD ++ +YVAYVAK
Sbjct: 142 QSISFASGGDPETAEYVAYVAK 163
Score = 131 bits (317), Expect = 3e-29
Identities = 70/144 (48%), Positives = 83/144 (57%), Gaps = 9/144 (6%)
Query: 272 NHHTDIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKEPWFHGPISRTT 331
N H D FDM+PF PL + Q E WFHG +SR
Sbjct: 391 NMHRDAFDMKPFDDALGVSGHSGTSSASAA----PPLVQQLQC-----EAWFHGGLSRKE 441
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE+L+ DG+FLVRES GQ+VLTG + G KHLLLVDP GVVRTKD F+SV HLI
Sbjct: 442 AERLLTRDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRFESVSHLIS 501
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
YH N LPI+SA S + L++PV R
Sbjct: 502 YHMDNRLPIISAGSEVCLKQPVER 525
Score = 61.3 bits (142), Expect = 5e-08
Identities = 34/77 (44%), Positives = 45/77 (58%), Gaps = 9/77 (11%)
Query: 154 ACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESACGLVEDRE-- 210
AC++LEC LAQ+VI+TIGQAFELRFK++L P L + + + + ED E
Sbjct: 220 ACHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKLVTPHDRMAPFDGSAWEEEDEEPP 279
Query: 211 ------YYNDMPDKVPP 221
YYN+ P K PP
Sbjct: 280 PPPDVPYYNNFPGKQPP 296
>UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 666
Score = 138 bits (334), Expect = 3e-31
Identities = 65/144 (45%), Positives = 97/144 (67%), Gaps = 2/144 (1%)
Query: 3 ESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARV 62
+ GSF+ KP++GWLHPD +A G +Y VRY+GC+EVL SM+ LDF+TR+QV +E I R+
Sbjct: 87 QKGSFIHKPSQGWLHPDKKIAGPGASYIVRYMGCIEVLKSMRSLDFNTRTQVTREAINRL 146
Query: 63 C-AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARH 121
C A G R A +K+ +++ A + + + + +G ++A+ +S ++L + IA H
Sbjct: 147 CEAVPGGRGAWRKKSMNK-ALQTVMGKSNLRFAGMSIAVNISIDGLSLLIPTTRQVIAHH 205
Query: 122 DMPRVSFASGGDADSLDYVAYVAK 145
M +SFASGGD D+ DYVAYVAK
Sbjct: 206 PMQSISFASGGDTDTPDYVAYVAK 229
Score = 129 bits (311), Expect = 2e-28
Identities = 61/99 (61%), Positives = 75/99 (75%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L +E W+H +SR AE+L++ DG+FLVREST GQ+VLTG GL KHLLLVDP GVV
Sbjct: 566 LRRETWYHSRMSRRDAERLLIRDGDFLVRESTTNLGQYVLTGMHCGLPKHLLLVDPEGVV 625
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD +FDS+ HLI YH NELPIV+A+S L L++ V R
Sbjct: 626 RTKDMLFDSISHLIAYHLKNELPIVAAESELHLKQAVRR 664
Score = 64.5 bits (150), Expect = 5e-09
Identities = 35/73 (47%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Query: 154 ACYVLECGGRLAQDVIATIGQAFELRFKEFLTKP--STLNLNGSLPSCESACGLVE---D 208
AC++LEC LAQ VI+TIGQAFEL+FK++L P S ++ S + E G E D
Sbjct: 323 ACHILECSDGLAQSVISTIGQAFELQFKQYLHSPPKSMASVERSARAEEPIWGEDEGFSD 382
Query: 209 REYYNDMPDKVPP 221
+YYN +P K PP
Sbjct: 383 HDYYNSIPGKEPP 395
>UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 520
Score = 126 bits (305), Expect = 8e-28
Identities = 60/99 (60%), Positives = 72/99 (72%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L E WFHGP+SR E L+ DG+FLVREST Q+VL+G + G KHLLLVDP G V
Sbjct: 418 LYNEEWFHGPMSRKEGEPLLSNDGDFLVRESTTAKDQYVLSGMQNGTPKHLLLVDPQGKV 477
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD+ FDSV HLI YH +N LPI+SA SA+ L+ PV+R
Sbjct: 478 RTKDKEFDSVSHLINYHRNNRLPIISAGSAVHLKTPVVR 516
Score = 83.4 bits (197), Expect = 1e-14
Identities = 47/112 (41%), Positives = 63/112 (56%), Gaps = 18/112 (16%)
Query: 76 RVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDAD 135
R S+ + + P + GANV LT+S+ +I + + E G IA H M +SFASGGDA
Sbjct: 58 RASKTICKIIGENPNILFGGANVNLTISTASINIRIKETGKPIANHQMQGISFASGGDAV 117
Query: 136 SLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKP 187
+ C+VLEC LAQDVI T+GQAFE+RFK++L P
Sbjct: 118 T------------------CHVLECLAGLAQDVITTVGQAFEIRFKDYLRNP 151
Score = 33.9 bits (74), Expect = 8.0
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 4 SGSFVAKPARGWLHPDSVLAS-DGVTYAVR 32
+G+F+ KP RGWLH + L GV Y VR
Sbjct: 29 TGTFINKPTRGWLHIEEELKDHGGVCYGVR 58
>UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant; n=9;
Tetrapoda|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant - Homo
sapiens (Human)
Length = 377
Score = 116 bits (279), Expect = 1e-24
Identities = 63/140 (45%), Positives = 83/140 (59%), Gaps = 8/140 (5%)
Query: 88 RPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSA 147
R + +G + LTVS+ ++ L + IA H M +SFASGGD D+ +YVAYVAK
Sbjct: 1 RSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKD- 59
Query: 148 PPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESACGLV 206
P RAC++LEC LAQDVI+TIGQAFELRFK++L P L + + + +
Sbjct: 60 -PVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDE 118
Query: 207 E-----DREYYNDMPDKVPP 221
E D +YYND P K PP
Sbjct: 119 EEEEPPDHQYYNDFPGKEPP 138
Score = 81.0 bits (191), Expect = 5e-14
Identities = 40/70 (57%), Positives = 48/70 (68%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 252 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 311
Query: 367 LLLVDPIGVV 376
LLLVDP GVV
Sbjct: 312 LLLVDPEGVV 321
>UniRef50_A3KNZ1 Cluster: Zgc:162768 protein; n=6;
Euteleostomi|Rep: Zgc:162768 protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 101
Score = 79.0 bits (186), Expect = 2e-13
Identities = 31/54 (57%), Positives = 43/54 (79%)
Query: 3 ESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAK 56
+ GSF+ KP++GWLHPD ++S G +Y VRY+GC+EVL SM+ LDF TR+QV +
Sbjct: 18 QKGSFINKPSQGWLHPDKKISSTGASYIVRYMGCIEVLKSMRSLDFSTRTQVTR 71
>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 76.6 bits (180), Expect = 1e-12
Identities = 39/97 (40%), Positives = 61/97 (62%), Gaps = 5/97 (5%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVRTKD 380
W+HG +SR A+ L+ +G+FLVR+S G++VL+G HKHL+L+D VRT+D
Sbjct: 211 WYHGNLSREDAQALLKTEGDFLVRQSDHTPGKYVLSGRTAENEHKHLILLDNHNRVRTRD 270
Query: 381 RVFDSVPHLIKYHCSNELPIVS----ADSALLLRKPV 413
R F ++ LI YH +N + + S +++L L +PV
Sbjct: 271 RTFSNISELIDYHVNNGMAVRSEGRDRETSLNLIRPV 307
Score = 50.8 bits (116), Expect = 7e-05
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 22 LASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSADKKRRVSQAA 81
L S GV+ + Y+G + V+ S+ + + R QV ECI V A G+ +A R ++
Sbjct: 12 LRSSGVSLSATYLGSVPVVESINVMVSEMRVQVVSECIQHVAATVGVTAA---REINPVV 68
Query: 82 ARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGD--ADSLDY 139
+R + + V + +SSK I +++ I RH SF + G D+
Sbjct: 69 SRVI---GEVKKENFPVDINISSKMI--KIIKQSRLIQRHPFSFFSFGAQGQKGTDTELM 123
Query: 140 VAYVAKSAPPTEWRACYVL 158
Y+AK+ T+ R C+V+
Sbjct: 124 FGYIAKNKDGTD-RRCHVV 141
>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
protein, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
protein, partial - Strongylocentrotus purpuratus
Length = 926
Score = 66.9 bits (156), Expect = 9e-10
Identities = 40/104 (38%), Positives = 60/104 (57%), Gaps = 10/104 (9%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL-------VDPIG 374
WFHG ISR AEKL+ E+G+FLVR+S + G FVLT +G+ H ++ P
Sbjct: 126 WFHGGISREKAEKLIRENGDFLVRDSISKPGNFVLTVRWKGVSMHFVVNKVVLKAHSPYA 185
Query: 375 VV--RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V + + FD++P LIK++ N P+ A A +++ PV R+
Sbjct: 186 SVQYQFEKECFDAIPSLIKFYVGNCRPVSQASGA-VIQHPVNRT 228
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 63.7 bits (148), Expect = 9e-09
Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
LA++ W+HG I R A++L+ + G+FLVRES G++VL+ G +H ++ +
Sbjct: 455 LAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMY 514
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
R + F ++P LI +H + + +++ S ++L P+
Sbjct: 515 RFEGTGFSNIPQLIDHHYTTK-QVITKKSGVVLLNPI 550
>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14724,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 803
Score = 62.5 bits (145), Expect = 2e-08
Identities = 36/109 (33%), Positives = 56/109 (51%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPI--- 373
L W+HG I R AE LV DG+FL+R+S + G +VLT R +H + +
Sbjct: 31 LRSHAWYHGAIPRQVAENLVQRDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKKVVAL 90
Query: 374 --GVVRTKDRV----FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
R + R+ FDSVP LI+++ N P+ A++ +P+ R+
Sbjct: 91 NEAYTRVEFRLEREGFDSVPALIRFYVGNRKPVSQVVGAIIF-QPINRA 138
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 62.1 bits (144), Expect = 3e-08
Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLL 368
T EA A + +EPW+HG ISR A L+ + G+FLVR S A + LT G+ KH +
Sbjct: 505 TPEAHAGV-EEEPWYHGEISRQEATGLLKKMGDFLVRYS-ADKEHYTLTVKMEGI-KHFI 561
Query: 369 LVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ R + + S+P LI +H N LP V+ S +LR+PV
Sbjct: 562 IQHNEEGFRFEGDPYPSIPMLIDHHFKNRLP-VTRKSQAILRQPV 605
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 61.3 bits (142), Expect = 5e-08
Identities = 40/101 (39%), Positives = 56/101 (55%), Gaps = 4/101 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTA-CAGQFVLTGARRGLHKHLLL-VDPIG 374
L +E WFHG + R +L+ +G+FLVRE+T Q VL+ G HKH ++ G
Sbjct: 823 LHEEEWFHGVLPREEVVRLLRNEGDFLVRETTRNDESQTVLSVCWNG-HKHFIVQTTAEG 881
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
R + F S+ LI + +ELP V+ S +LRKPVLR
Sbjct: 882 HYRFEGPAFPSIQELIVHQYQSELP-VTGRSGAVLRKPVLR 921
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 60.1 bits (139), Expect = 1e-07
Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV-----D 371
L + W+HG + R E+L+ DGEFLVR+S+ AG +VLT + H ++
Sbjct: 22 LRSQAWYHGQLQREATEQLLGRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIRITLRP 81
Query: 372 PIGVVRT----KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G R ++ FD++P LI++H PI + A++ +P+ R+
Sbjct: 82 KQGYTRELFQFENDQFDNIPALIRFHVGGRRPISHSTGAVIF-QPITRT 129
>UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance
protein 3; n=34; Euteleostomi|Rep: Breast cancer
anti-estrogen resistance protein 3 - Homo sapiens
(Human)
Length = 825
Score = 60.1 bits (139), Expect = 1e-07
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 58.8 bits (136), Expect = 2e-07
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 14/119 (11%)
Query: 311 EAQAALLAKEP----WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
E + L ++EP W+HG I R AE LV DG+FL+R+S + G +VLT + +H
Sbjct: 31 EEELKLSSEEPRSHAWYHGAIPRQVAENLVQRDGDFLIRDSLSSPGNYVLTCQWKNSPQH 90
Query: 367 LLL-VDPIGVVRTKDRV--------FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ + + RV FDS+P L++Y+ N P+ A++ +P+ R+
Sbjct: 91 FKINKRVVAMNEAYSRVQYLFEKEGFDSIPALVRYYVGNREPVSEVIGAIIF-QPINRA 148
>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
n=2; Endopterygota|Rep: Signal transduction protein
lnk-realted - Aedes aegypti (Yellowfever mosquito)
Length = 564
Score = 58.8 bits (136), Expect = 2e-07
Identities = 32/98 (32%), Positives = 58/98 (59%), Gaps = 6/98 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVED-----GEFLVRESTACAGQFVLTGARRGLHKHL-L 368
A++ + PWFHG ++R+ A +LV+ + G FLVR+S G+FVLT +G KHL +
Sbjct: 412 AMMREYPWFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRM 471
Query: 369 LVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
++ +G R + F S+ ++++ + +P+ S +A
Sbjct: 472 TLNDLGQCRVQHLWFPSITEMLEHFRQHPIPLESGGTA 509
>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 724
Score = 58.8 bits (136), Expect = 2e-07
Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 9/99 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHL----LLVDP 372
L W+HGPI R AE++V DG+FLVR+ + G +VLT +G H LL+ P
Sbjct: 20 LRSHAWYHGPIPRQRAEEIVQRDGDFLVRDCVSQPGNYVLTCKTKGPTLHFVINKLLIQP 79
Query: 373 IGV-----VRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
V + +D +D+VP LI ++ + I +A A
Sbjct: 80 ETVYERVQYQFEDDAYDTVPDLITFYVGSGKAISAASGA 118
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 58.0 bits (134), Expect = 4e-07
Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
L E WFHG + R +L+ +DG+FLVRE+T + G HKH ++ G
Sbjct: 431 LVDEEWFHGVLPREEVVRLLTQDGDFLVRETTRNDECQTVLSVCWGGHKHFIVQTTAEGH 490
Query: 376 VRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
R + F S+ LI Y ++ LP+ ALL KP+ R
Sbjct: 491 YRFEGPAFPSIRDLILYQYTSGLPVTGRSGALLY-KPIPR 529
>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
Xenopus tropicalis
Length = 419
Score = 57.6 bits (133), Expect = 6e-07
Identities = 34/110 (30%), Positives = 61/110 (55%), Gaps = 11/110 (10%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLT---GARRGLHKHLLLV--- 370
L W+HGP+ R AE+L+V +G+FL+R+S + G +VL+ + LH ++ V
Sbjct: 10 LRSHAWYHGPLPRQDAERLLVSNGDFLIRDSISSPGDYVLSCFCAGGQPLHFKIIAVALR 69
Query: 371 DPIGVVRT----KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G+ RT + FD++P L++ + + + + A+++R PV RS
Sbjct: 70 PRRGIARTLYQLEQDQFDNIPALVRSYVGDRRKVSESTGAVIIR-PVNRS 118
>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
Xenopus tropicalis
Length = 514
Score = 57.6 bits (133), Expect = 6e-07
Identities = 34/110 (30%), Positives = 61/110 (55%), Gaps = 11/110 (10%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLT---GARRGLHKHLLLV--- 370
L W+HGP+ R AE+L+V +G+FL+R+S + G +VL+ + LH ++ V
Sbjct: 23 LRSHAWYHGPLPRQDAERLLVSNGDFLIRDSISSPGDYVLSCFCAGGQPLHFKIIAVALR 82
Query: 371 DPIGVVRT----KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G+ RT + FD++P L++ + + + + A+++R PV RS
Sbjct: 83 PRRGIARTLYQLEQDQFDNIPALVRSYVGDRRKVSESTGAVIIR-PVNRS 131
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 57.2 bits (132), Expect = 7e-07
Identities = 32/99 (32%), Positives = 58/99 (58%), Gaps = 2/99 (2%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L ++ W+HG I R ++L+ +DG+FLVR+S G +VL+ G KH L+ + +
Sbjct: 523 LEQQTWYHGAIPRLEVQQLLTKDGDFLVRKSQEKPG-YVLSVHWSGACKHFLVQNKDNMY 581
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
F ++P LI+ + +++ V+ S ++LR+PVL+
Sbjct: 582 CLDGESFHTIPQLIQQYQTSQ-QHVTKKSEVVLRRPVLK 619
>UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12;
Eumetazoa|Rep: Tyrosine-protein kinase Fps85D -
Drosophila melanogaster (Fruit fly)
Length = 1325
Score = 57.2 bits (132), Expect = 7e-07
Identities = 38/101 (37%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTAC-AGQFVLTGARRGLHKHLLL-VDPIG 374
L +E WFHG + R +L+ DG+FLVRE+ Q VL+ G HKH ++ G
Sbjct: 955 LYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNG-HKHFIVQTTGEG 1013
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
R + F S+ LI + +ELP V+ S +LR+PV R
Sbjct: 1014 NFRFEGPPFASIQELIMHQYHSELP-VTVKSGAILRRPVCR 1053
>UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 948
Score = 56.0 bits (129), Expect = 2e-06
Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
Query: 311 EAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQF---VLTGARRGLHKHL 367
++ A L K PWFHG I+ AE L+ GEFLVRE A G + V + LH +
Sbjct: 47 DSAARQLEKSPWFHGKITAEYAEMLMRGAGEFLVREDPAMPGMYFIAVRNKEQETLHLAI 106
Query: 368 LLVDPIGVVRTKDRV------FDSVPHLIKYHCSNELPIVSADSALL 408
V+ R K RV FD +P LI+++ S P+ A+L
Sbjct: 107 TKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYISERRPVSIRPPAVL 153
>UniRef50_O76337 Cluster: Cell death protein 6; n=2;
Caenorhabditis|Rep: Cell death protein 6 -
Caenorhabditis elegans
Length = 492
Score = 56.0 bits (129), Expect = 2e-06
Identities = 43/177 (24%), Positives = 80/177 (45%), Gaps = 24/177 (13%)
Query: 13 RGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSAD 72
R W+HP L + V Y R++GC+E + S VA+E I + L+ ++
Sbjct: 45 RTWIHPPDYLINGHVEYVARFLGCVETPKA-------NGSDVAREAIHAIRFQRDLKRSE 97
Query: 73 KKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGG 132
+ R ++ V + +S + +A ++ + + R+SF +
Sbjct: 98 QTRETAKLQ---------------KVEIRISIDNVIIADIKTKAPMYTFPLGRISFCAD- 141
Query: 133 DADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPST 189
D D +++A++ + +CY +LA+D+ TIG+AF+L +K FL K T
Sbjct: 142 DKDDKRMFSFIARAEGASGKPSCYAFT-SEKLAEDITLTIGEAFDLAYKRFLDKNRT 197
>UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG17367-PB, isoform B - Tribolium castaneum
Length = 488
Score = 55.6 bits (128), Expect = 2e-06
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L KE WFHG + R+ A LV+ DG FLVR+S G+FVLT +G KHL + +
Sbjct: 317 LKKEFWFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHLRMTI 376
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ +P+ S ++
Sbjct: 377 NDQGQCRVQHFWFQSIYEMLEHFRQQPIPLESGGNS 412
>UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Xenopus tropicalis|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Xenopus tropicalis
Length = 321
Score = 55.6 bits (128), Expect = 2e-06
Identities = 37/90 (41%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV----VE-DGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
LA PWFHGPISR A +LV VE G FLVR+S G++VLT +G KHL L +
Sbjct: 218 LASSPWFHGPISRVKAAQLVQSQGVEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLTL 277
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPI 400
G + F SV +++Y +P+
Sbjct: 278 TERGQCHVQHLRFRSVLEMLQYFRLQPIPL 307
>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
Drosophila melanogaster (Fruit fly)
Length = 723
Score = 55.6 bits (128), Expect = 2e-06
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVED-----GEFLVRESTACAGQFVLTG 358
+ A LTAE ++ PWFHG ++R+ A ++V+ G FLVR+S G+FVLT
Sbjct: 429 DVADLTAE-----MSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTF 483
Query: 359 ARRGLHKHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+G KHL L + G R + F S+ ++++ N +P+ S ++
Sbjct: 484 NFQGRAKHLRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESGGTS 532
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 55.2 bits (127), Expect = 3e-06
Identities = 35/104 (33%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT--GARRGLHKHLLLV-- 370
L K+ WFHG I+R AE ++ + +G FLVR S + + L+ AR +H +
Sbjct: 765 LEKQGWFHGAITRVEAENVLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDGN 824
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
D ++ + F S+P +I++ C N LPI A+ LL +PV+
Sbjct: 825 DECYILGQFSKPFHSIPEMIRHFCINRLPIRGAEHMCLL-QPVI 867
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 55.2 bits (127), Expect = 3e-06
Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT--GARRGLHKHLLLVDP 372
L ++ W+HG ISR AEK++ + +G FLVR S + + LT A+ +H +
Sbjct: 604 LDRQGWYHGSISRIDAEKILRPLSEGSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDAD 663
Query: 373 IG--VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
G ++ R F ++P +I++ C N LP+ A+ LL +PV+
Sbjct: 664 SGQFILGQFSRPFPTIPDMIRHFCLNRLPVRGAEHMCLL-EPVI 706
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 55.2 bits (127), Expect = 3e-06
Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT--GARRGLHKHLLLVDP 372
L ++ W+HG ISR AEK++ + +G FLVR S + + LT A+ +H +
Sbjct: 938 LDRQGWYHGSISRIDAEKILRPLGEGSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDHE 997
Query: 373 IG--VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
G ++ R F ++P +I++ C N LP+ A+ LL +PV+
Sbjct: 998 TGQFILGQFSRPFPTIPDMIRHFCLNRLPVRGAEHMCLL-EPVI 1040
>UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16;
Euteleostomi|Rep: SH2B adapter protein 2 - Mus musculus
(Mouse)
Length = 621
Score = 55.2 bits (127), Expect = 3e-06
Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 7/120 (5%)
Query: 304 ECAPLTAEAQAAL-LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLT 357
E A L +A+A L L+ PWFHG +SR A +LV+ G F++R+S G+ VLT
Sbjct: 390 EGAELDTDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLT 449
Query: 358 GARRGLHKHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+G KHL L ++ G + F SV ++++ ++ +P+ S SA + + +R+
Sbjct: 450 FNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRA 509
>UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;
Eutheria|Rep: SH2 domain-containing protein 3A - Homo
sapiens (Human)
Length = 576
Score = 55.2 bits (127), Expect = 3e-06
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLV---- 370
LA +PW+HG +SR AE L+ ++G+FLVR S + G V++ RG LH + V
Sbjct: 10 LAGQPWYHGLLSRQKAEALLQQNGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRP 69
Query: 371 ---DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
P + + +D F S+P L+ + + P+ A A++ R
Sbjct: 70 RPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSR 112
>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
isoform A, partial; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to CG9098-PA, isoform A, partial -
Tribolium castaneum
Length = 851
Score = 54.4 bits (125), Expect = 5e-06
Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 9/99 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHL----LLVDP 372
L W+HG I R+ AE +V E+G FLVR+ T+ G +VLT + H +++ P
Sbjct: 171 LRSHAWYHGAIPRSRAEDIVREEGGFLVRDCTSQPGNYVLTCRTKTQPLHFVINKIILQP 230
Query: 373 IGV-----VRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
V + ++ FD+VP LI ++ + PI +A A
Sbjct: 231 DTVYEHVQFQFEEDAFDTVPDLITFYVGSGKPITAASGA 269
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 54.4 bits (125), Expect = 5e-06
Identities = 34/83 (40%), Positives = 48/83 (57%), Gaps = 6/83 (7%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLV-D 371
L+KE W+HG ISR AE+L+ G FLVR+S G++VL+ + +G H ++
Sbjct: 4 LSKELWYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRH 63
Query: 372 PIGVVRTKDRV-FDSVPHLIKYH 393
P G V +D FDS LI+YH
Sbjct: 64 PDGSVAIQDGAKFDSPIELIQYH 86
Score = 39.5 bits (88), Expect = 0.16
Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Query: 319 KEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
K+ WFHG ISR +E+ + + DG FLVRE T + + ++ +LL ++ +G
Sbjct: 160 KQLWFHGAISREESEQRMKAFGLRDGLFLVRERTEVNSFALCVAVKNDIYHYLLEMNTLG 219
Query: 375 VVRTKD-RVFDSVPHLIKYH 393
+ ++ R F+++ ++ ++
Sbjct: 220 QLSIENGRKFENLLQVVDHY 239
>UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus
norvegicus|Rep: SH2B adapter protein 3 - Rattus
norvegicus (Rat)
Length = 368
Score = 54.4 bits (125), Expect = 5e-06
Identities = 33/86 (38%), Positives = 49/86 (56%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S + G++VLT +G KHL L++ G
Sbjct: 118 PWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERG 177
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++++ + +P+
Sbjct: 178 QCRVQHLHFPSVVDMLRHFQRSPIPL 203
>UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 18
SCAF14547, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 609
Score = 54.0 bits (124), Expect = 7e-06
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 12/110 (10%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPI--- 373
L+ W+HGP+ R AE L+ +G+FLVR+S++ +VLT + H ++ +
Sbjct: 16 LSSHAWYHGPLRREAAEALLERNGDFLVRDSSSTPRDYVLTCFWMNMPMHFKIIRVVLRP 75
Query: 374 --GVVR-----TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G R +DR FD++P LI+ + PI A A ++ P+ R+
Sbjct: 76 KKGYSRELFQFEEDR-FDNIPALIRLYVGGRRPISQASGA-VISHPITRT 123
>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
(Human)
Length = 632
Score = 53.6 bits (123), Expect = 9e-06
Identities = 36/113 (31%), Positives = 62/113 (54%), Gaps = 7/113 (6%)
Query: 311 EAQAAL-LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARRGLH 364
EA+ L L+ PWFHG +SR A +LV+ G F++R+S G++VLT +G
Sbjct: 405 EAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKA 464
Query: 365 KHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
KHL L ++ G + F SV ++++ ++ +P+ S SA + + +R+
Sbjct: 465 KHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRA 517
>UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Bos taurus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Bos Taurus
Length = 526
Score = 52.8 bits (121), Expect = 2e-05
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S G++VLT +G+ KHL L + G
Sbjct: 427 PWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG 486
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++ + + +P+
Sbjct: 487 QCRVQHLHFPSVVDMLHHFQRSPIPL 512
>UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF15007, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 868
Score = 52.8 bits (121), Expect = 2e-05
Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL------- 369
L W+HGPI +E LVV G+FL+R+S + G FVLT + H L+
Sbjct: 275 LKSHAWYHGPIPWEVSESLVVNHGDFLIRDSQSNRGNFVLTSNWQQKTLHFLIRKAALQP 334
Query: 370 --VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
P ++ F+S+P L+ ++ + P+ A +++PV R+
Sbjct: 335 GETYPRVQYSLEEEAFESLPALVHFYVGSRAPLTQWSGA-QIQRPVNRT 382
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 52.8 bits (121), Expect = 2e-05
Identities = 31/81 (38%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 323 FHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGV-VRTK 379
F G + RT AE+ + DG FLVRES AG++ L+ R KH+ + G T+
Sbjct: 661 FAGKMDRTEAEQETMGRSDGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCLTQ 720
Query: 380 DRVFDSVPHLIKYHCSNELPI 400
+VFDS+P L+ Y+ N L +
Sbjct: 721 SKVFDSIPELVAYYRENTLGV 741
>UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15;
Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens
(Human)
Length = 575
Score = 52.8 bits (121), Expect = 2e-05
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S G++VLT +G+ KHL L + G
Sbjct: 363 PWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG 422
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++ + + +P+
Sbjct: 423 QCRVQHLHFPSVVDMLHHFQRSPIPL 448
>UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n=4;
Euteleostomi|Rep: UPI00015A3F46 UniRef100 entry - Danio
rerio
Length = 217
Score = 52.0 bits (119), Expect = 3e-05
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 7/105 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARR 361
P E A+L + PWFHG +SR A +LV+ G F++R+S G++VLT +
Sbjct: 103 PREGEGDASL-SGYPWFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQ 161
Query: 362 GLHKHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADS 405
G KHL L V+ G F +V ++++ ++ +P+ S S
Sbjct: 162 GKAKHLRLSVNDSGQCHVHHLWFQTVADMLRHFHTHPIPLESGGS 206
>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
(Novel SH2-containing protein 3).; n=1; Takifugu
rubripes|Rep: SH2 domain-containing protein 3C (Novel
SH2-containing protein 3). - Takifugu rubripes
Length = 580
Score = 52.0 bits (119), Expect = 3e-05
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLT--GARRGLH---KHLLLVD 371
L W+HGP+ AE LVV GEFL+R+S + G FVLT ++ LH + +L
Sbjct: 31 LKSHAWYHGPVPWEVAESLVVNHGEFLIRDSRSNHGDFVLTCHWQQKTLHFLIRRTVLQS 90
Query: 372 PIGVVRT----KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
R ++ FDS+P L+ ++ ++ + A + +P+ R+
Sbjct: 91 SETYTRVQYSLEEEAFDSLPALVHFYVGSKAALTQWSGA-QIHRPINRT 138
>UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular
organisms|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 52.0 bits (119), Expect = 3e-05
Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 7/102 (6%)
Query: 319 KEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD-PIGVVR 377
+E WF+ + R AE+ G++L+R S+ ++VLT G KH ++ + P +
Sbjct: 523 EERWFYPNMERKEAEEKCKNTGDYLIRYSSK-QNRYVLTVCWAGQGKHFVIQEAPDEQTK 581
Query: 378 TK----DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
TK R F SV L+ +H +++ P+ A A+L R P+LR
Sbjct: 582 TKYRFESRSFPSVRELLDFHVNSQTPVTKASGAILSR-PILR 622
>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
Length = 1283
Score = 52.0 bits (119), Expect = 3e-05
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 13/111 (11%)
Query: 319 KEPWFHGPIS--RTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDP 372
KE WFHG ++ R AEKL+ + +G FLVREST G + L+ R G + H +
Sbjct: 541 KEKWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTK 600
Query: 373 IGVVRTK-----DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSSS 418
+T+ +FDS+ LI ++ SN P+ S +L +PV + +S
Sbjct: 601 SEGGKTRFYLIDQTLFDSIYELIMHYKSN--PLKSPTFEQVLAEPVPQQNS 649
Score = 43.2 bits (97), Expect = 0.013
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 8/85 (9%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVR--ESTACAGQ--FVLTGARRGLHKHLLL-VDPI 373
WFH +SR+ AE+++ + DG FL+R E AGQ + ++ G KH + VD
Sbjct: 655 WFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVDES 714
Query: 374 GVVRTKDRVFDSVPHLIKYHCSNEL 398
G +FDS+ L++Y+ +N L
Sbjct: 715 GQYCIGSAIFDSLTELVQYYEANPL 739
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 52.0 bits (119), Expect = 3e-05
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 215 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 274
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 275 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 322
>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
transduction protein lnk-realted; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to signal
transduction protein lnk-realted - Nasonia vitripennis
Length = 458
Score = 51.6 bits (118), Expect = 4e-05
Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVVED-----GEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L + PWFHG + R+ A +LV+ + G FLVR+S G++VLT +G KHL + +
Sbjct: 265 LREYPWFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRMTL 324
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
G R + F ++ ++ + N +P+ S +A
Sbjct: 325 TDQGHCRVQHLSFPAIYDMLDHFRQNPIPLESGGTA 360
>UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5;
Euteleostomi|Rep: Sh2d3c-prov protein - Xenopus laevis
(African clawed frog)
Length = 676
Score = 51.6 bits (118), Expect = 4e-05
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 13/98 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKD- 380
W+HG I R +E LV +G+FL+R+S G +VLT + H ++ + +V+T D
Sbjct: 39 WYHGRIPREVSESLVQRNGDFLIRDSLTSLGDYVLTCRWKNESLH-FKINKV-MVKTSDS 96
Query: 381 --RV--------FDSVPHLIKYHCSNELPIVSADSALL 408
R+ FD++P L++Y+ + P+ SA++
Sbjct: 97 YTRIQYLFEQESFDNIPALVRYYVGSRRPVSEQSSAMI 134
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 51.6 bits (118), Expect = 4e-05
Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 6/103 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVR--ESTACAGQFVLTGARRGLHKHLLLVDP 372
L ++ W+HG I+R AE + + +G FLVR EST L GA+ +H + +
Sbjct: 1311 LERQGWYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNET 1370
Query: 373 IGVVRTK-DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
+ + R F++VP +I++ C N LP+ A+ L+ +PV+
Sbjct: 1371 GQYILGQFSRPFETVPEMIRHFCLNRLPVRGAEHMCLI-EPVI 1412
>UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Gallus gallus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Gallus gallus
Length = 506
Score = 51.2 bits (117), Expect = 5e-05
Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV----VE-DGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHGPISR A +LV +E G FLVR+S G++VLT +G KHL L +
Sbjct: 383 LSSCPWFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLSL 442
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPI 400
G R + F S+ ++ + +P+
Sbjct: 443 TERGQCRVQHLRFSSITEMLHHFHRYPIPL 472
>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
CG9098-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 944
Score = 51.2 bits (117), Expect = 5e-05
Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 9/101 (8%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHL----LLVDP 372
L W+HG + R AE++V +G+FLVR+ + +VL+ + H L++ P
Sbjct: 235 LRSHAWYHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQP 294
Query: 373 IGV-----VRTKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
V + ++ FD+VP LI ++ + PI SA AL+
Sbjct: 295 ETVYERVQYQFEEDAFDTVPDLITFYVGSGKPISSASGALI 335
>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
(Human)
Length = 756
Score = 51.2 bits (117), Expect = 5e-05
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 522 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 581
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 582 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 617
>UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia
roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea
squirt)
Length = 867
Score = 50.8 bits (116), Expect = 7e-05
Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 15/106 (14%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDR 381
WFHG + R AE L+ +G+FL+RES AG+FVLT + H + +
Sbjct: 51 WFHGRMPRDIAEDLIRREGDFLIRESVNNAGEFVLTCKYKSATYHFKINKK--TMPKVSS 108
Query: 382 VFDSV------------PHLIKYHCSNELPIVSADSALLLRKPVLR 415
VFDS P + YH ++P VS S ++L +PV R
Sbjct: 109 VFDSAILVWRMTISIPFPLSVYYHVGKKIP-VSKKSGVILSQPVNR 153
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 50.8 bits (116), Expect = 7e-05
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRG-LHKHLLLVDPI 373
L K W+HGPISR AE L+ +G FLVRES + GQ ++ G ++ + + DP
Sbjct: 249 LEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPD 308
Query: 374 G-VVRTKDRVFDSVPHLIKYH 393
G V T++ F+++ L+ +H
Sbjct: 309 GKVFVTQEAKFNTLAELVHHH 329
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 50.4 bits (115), Expect = 9e-05
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRG-LHKHLLL 369
A L K+ W+HG ISR AE L+ ++ +LVR S + L+ + +G +H L
Sbjct: 402 AVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAK 461
Query: 370 VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V+ FDSVP +I Y+ + +LPI A+ LL +R+
Sbjct: 462 TKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRT 508
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 50.0 bits (114), Expect = 1e-04
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 7/105 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD--- 371
L PW+ G ISR A+ ++ DG FLVR++ + G++ LT + G K + +
Sbjct: 27 LRMAPWYWGRISREEAKSILHGKPDGSFLVRDALSMKGEYTLTLMKDGCEKLIKICHMDR 86
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G + T +F+SV +I Y+ N L + + + L P++R+
Sbjct: 87 KYGFIETD--LFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRA 129
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT--GARRGLHKHLLLVDP 372
L ++ W+HG I+R AE ++ + +G +LVR S + + L+ AR +H + +
Sbjct: 1076 LERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEE 1135
Query: 373 IG--VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
+ ++ + FDS+P ++++ N LPI A+ LL PV+
Sbjct: 1136 LNAYILGQFSKPFDSIPEMVRHFSINRLPIRGAEHMCLLH-PVI 1178
>UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 457
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQF--VLTGARRGLHKHLLLVDP 372
L K+ W+HG +SR AE + + + FLVR+S + ++ L ++ +H +
Sbjct: 353 LEKQSWYHGSVSRQEAEAQLQQCREASFLVRDSESATSKYSIALKTSQGCVHIIVAQTKE 412
Query: 373 IGVVRTKDR-VFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G K VF S+P ++ ++C+ LP A+ + L+ PV R+
Sbjct: 413 CGYTLEKSSCVFPSIPEVVHHYCTQRLPFTGAEH-MTLQHPVPRT 456
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT--GARRGLHKHLLLVDP 372
L ++ W+HG I+R AE ++ + +G +LVR S + + L+ AR +H + +
Sbjct: 1016 LERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEE 1075
Query: 373 IG--VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
+ ++ + FDS+P ++++ N LPI A+ LL PV+
Sbjct: 1076 LNAYILGQFSKPFDSIPEMVRHFSVNRLPIRGAEHMCLLH-PVI 1118
>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
SH2D3C protein - Gallus gallus
Length = 603
Score = 49.2 bits (112), Expect = 2e-04
Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LH---KHLLLVD 371
L W+HG I R +E LV +G+F++R+S G +VLT R LH + +
Sbjct: 58 LRSHAWYHGRIPREVSESLVQRNGDFIIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKS 117
Query: 372 PIGVVRT----KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G R + FD+VP L++++ N +S S ++ P+ R+
Sbjct: 118 SDGRTRVQYLFEQESFDNVPALVRFYVGNR-KAISEQSGAIVYCPINRT 165
>UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 474
Score = 49.2 bits (112), Expect = 2e-04
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 3/82 (3%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTAC-AGQFVLTGARRGLHKHLLLVDPI 373
ALL EP++HG +SR +EKLV GEFL+R++ G+ V+ H L+V+
Sbjct: 84 ALLDDEPFYHGYMSREESEKLVRSQGEFLLRKTELTKRGEVVVLSVFWDEGVHHLVVEKA 143
Query: 374 --GVVRTKDRVFDSVPHLIKYH 393
G+ K+ F+++ L++YH
Sbjct: 144 NNGLYYLKEFCFENISDLVRYH 165
>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
n=13; Mammalia|Rep: SH2 domain-containing adapter
protein D - Homo sapiens (Human)
Length = 340
Score = 49.2 bits (112), Expect = 2e-04
Identities = 33/98 (33%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKL--VVEDGEFLVR--ESTACAGQFVLTGARRGLH-KHLLLVD 371
L K+PWFHGP++R AE L + ++G +LVR E+ L ++ LH K +
Sbjct: 235 LEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRE 294
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
V+ F SVP L+ ++ S LP+ A+ LL
Sbjct: 295 NQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALL 332
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 48.8 bits (111), Expect = 3e-04
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 306 APLTAEAQAAL-LAKEPWFHGPISRTTAEKL--VVEDGEFLVRESTACAGQFVLT--GAR 360
+PL AL L + W+HG ISRT AE L + ++ +LVR S F L+ ++
Sbjct: 329 SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ 388
Query: 361 RGLHKHLLLV-DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+H L + V+ F SVP ++ ++ S +LPI A+ LL +R+
Sbjct: 389 GFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 445
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 48.8 bits (111), Expect = 3e-04
Identities = 29/78 (37%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 320 EPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR 377
+PWFH ISR EKL+ DG FLVREST G F L + G +H + G
Sbjct: 149 QPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQL 208
Query: 378 T--KDRVFDSVPHLIKYH 393
T K+ F ++ L+ ++
Sbjct: 209 TCDKEEYFSNLTQLVSHY 226
>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
str. PEST
Length = 1230
Score = 48.8 bits (111), Expect = 3e-04
Identities = 39/106 (36%), Positives = 57/106 (53%), Gaps = 14/106 (13%)
Query: 320 EPWFHGPIS--RTTAEKLVVE-----DGEFLVRESTACAGQFVLTGARRGLHKH--LLLV 370
E WFHG +S R AEKL+ + DG FLVRES G + L+ R+G H + L
Sbjct: 568 ENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIKLK 627
Query: 371 DPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
GV + ++ +F+S+ LI Y+ N L SA+ + L++PV
Sbjct: 628 QDKGVTKYYLMENVLFESLYSLIMYYRQNALR--SAEFYITLKEPV 671
>UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate
lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel
protein similar to vertebrate lymphocyte adaptor protein
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 279
Score = 48.4 bits (110), Expect = 3e-04
Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE-----DGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ WFHGPISR A LV G FLVR+S G +VLT +G KHL L +
Sbjct: 114 LSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSL 173
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPI 400
G R + F SV ++ + + +P+
Sbjct: 174 TEWGQCRVQHLRFPSVMDMLSHFRNCPIPL 203
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 48.4 bits (110), Expect = 3e-04
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 306 APLTAEAQAAL-LAKEPWFHGPISRTTAEKL--VVEDGEFLVRESTACAGQFVLT--GAR 360
+PL AL L + W+HG ISRT AE L + ++ +LVR S F L+ ++
Sbjct: 363 SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ 422
Query: 361 RGLHKHLLLV-DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+H L + V+ F SVP ++ ++ S +LPI A+ LL +R+
Sbjct: 423 GFMHMKLSRTKNNKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 479
>UniRef50_Q4S8K3 Cluster: Chromosome 2 SCAF14705, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2
SCAF14705, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 487
Score = 48.0 bits (109), Expect = 5e-04
Identities = 26/61 (42%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AAL +PWFHG +SR A++L+ + DG FL+RES A FVL+ + KH L+
Sbjct: 360 AALHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHAQCFVLSLCHKLKIKHYLV 419
Query: 370 V 370
+
Sbjct: 420 I 420
>UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio
rerio|Rep: SH2 domain containing 3C - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 635
Score = 48.0 bits (109), Expect = 5e-04
Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLT--GARRGLH----KHLL-L 369
L+ W+HG I +E LV ++G+FL+R+S + G +VLT ++ LH K LL
Sbjct: 45 LSSHGWYHGRIPWEVSESLVQQEGDFLIRDSLSSIGDYVLTCRWNQKALHFLITKVLLRS 104
Query: 370 VDPIGVVR--TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
D V+ ++ F SVP L+ + N+ P+ + SA + PV R+
Sbjct: 105 YDTYTRVQYILEEETFYSVPALVHSYVGNKRPL-TKKSAAYIYSPVNRT 152
>UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E;
n=16; Euteleostomi|Rep: SH2 domain-containing adapter
protein E - Homo sapiens (Human)
Length = 495
Score = 48.0 bits (109), Expect = 5e-04
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV---D 371
L K+PW+HG ISR AE + ++ +LVR S + ++ + H+++ D
Sbjct: 390 LEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKD 449
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ VFDS+P ++ Y+ + +LP A+ LL
Sbjct: 450 NKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLL 487
>UniRef50_UPI0000F2C9D9 Cluster: PREDICTED: similar to
SHC-transforming protein 2 (SH2 domain protein C2) (Src
homology 2 domain-containing-transforming protein C2)
(Protein Sck); n=1; Monodelphis domestica|Rep:
PREDICTED: similar to SHC-transforming protein 2 (SH2
domain protein C2) (Src homology 2
domain-containing-transforming protein C2) (Protein Sck)
- Monodelphis domestica
Length = 265
Score = 47.6 bits (108), Expect = 6e-04
Identities = 23/42 (54%), Positives = 29/42 (69%)
Query: 376 VRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSS 417
VRTKD +F+S+ HLI YH N PI++A+S L LR V R S
Sbjct: 224 VRTKDVLFESISHLIDYHLQNGQPILAAESELHLRDVVKRES 265
Score = 41.9 bits (94), Expect = 0.030
Identities = 16/31 (51%), Positives = 21/31 (67%)
Query: 2 AESGSFVAKPARGWLHPDSVLASDGVTYAVR 32
+ GSF+ KP +GWLHPD + GV+Y VR
Sbjct: 150 SRKGSFIHKPPQGWLHPDDRVLGPGVSYIVR 180
>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
Zgc:158474 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 906
Score = 47.6 bits (108), Expect = 6e-04
Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L++ WFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 710 LSECQWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 769
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S ++
Sbjct: 770 NEDGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGAS 805
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 47.6 bits (108), Expect = 6e-04
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L EPWF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 4
SCAF14752, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 721
Score = 47.2 bits (107), Expect = 8e-04
Identities = 21/44 (47%), Positives = 28/44 (63%)
Query: 314 AALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLT 357
AA + W+HG I R +E LV+ +G+FLVR+S G FVLT
Sbjct: 29 AADIRSHGWYHGHIPREVSETLVLRNGDFLVRDSLTSVGDFVLT 72
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 47.2 bits (107), Expect = 8e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 46.8 bits (106), Expect = 0.001
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++ G
Sbjct: 13 LSLMPWFHGKITRNQAEQLLCPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNG 72
Query: 375 -VVRTKDRVFDSVPHLIKYH 393
+ ++ F+++ L++++
Sbjct: 73 KLTIDEEEYFENLMQLVEHY 92
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 46.8 bits (106), Expect = 0.001
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRG-LHKH 366
A A L PWFHG ISR AEKL+ ++G FLVRES G + L + G + +
Sbjct: 97 ASKGAVQLKTMPWFHGRISREDAEKLLTPPKNGRFLVRESQNYPGDYTLCVSYDGRVENY 156
Query: 367 LLLVDPIGVVRT-KDRVFDSVPHLIKYH 393
+ + G+V D FD++ L++++
Sbjct: 157 RVRRNEKGLVTVDDDEYFDNLIKLVEHY 184
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 46.8 bits (106), Expect = 0.001
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 321 PWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
PWFHG ISR AE L++ EDG FLVRES G + L + H + G +
Sbjct: 100 PWFHGKISRELAESLLMPREDGLFLVRESAHFPGDYTLCVCFQDQVDHYRMQGKNGKLTI 159
Query: 379 KDRV-FDSVPHLIKYH 393
+ V F S+ L++++
Sbjct: 160 DEEVYFSSLEELVQHY 175
>UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
LD41184p - Nasonia vitripennis
Length = 858
Score = 46.4 bits (105), Expect = 0.001
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 12/100 (12%)
Query: 322 WFHG---PISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHL----LLVDPIG 374
W+HG P R AE + DG+FLVR+ ++ G +VL+ +G H L++ P
Sbjct: 168 WYHGSSLPGGRKGAEAEIPNDGDFLVRDCSSQPGNYVLSVRHKGQALHFVINKLVLQPDT 227
Query: 375 V-----VRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
V + +D FD+V L+ ++ ++ PI A A ++
Sbjct: 228 VYERVQYQLEDEAFDTVADLVTFYVGSKRPISQASGARIV 267
>UniRef50_UPI000051A3DF Cluster: PREDICTED: similar to ced-6
CG11804-PC, isoform C; n=2; Apocrita|Rep: PREDICTED:
similar to ced-6 CG11804-PC, isoform C - Apis mellifera
Length = 459
Score = 46.4 bits (105), Expect = 0.001
Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 29/174 (16%)
Query: 13 RGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSAD 72
R W+HP L + Y V+Y+G EV D +V KE I ++ LR ++
Sbjct: 27 RNWIHPPDALQKGHIAYLVKYLGSTEV-------DQPKGIEVVKEAICKLKFNQQLRKSE 79
Query: 73 KKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMP--RVSFAS 130
T P++ + +++ AI + H P R+S+ +
Sbjct: 80 G------------TKTPKVE-----LTISIDGVAIQEPKTKTSSKRIMHQYPLHRISYCA 122
Query: 131 GGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFL 184
D + +++AK E C+V +LA+++ TIGQAF+L ++ FL
Sbjct: 123 D-DKGEKKFFSFIAKEEG-AERHTCFVF-VSDKLAEEITLTIGQAFDLAYRRFL 173
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 46.0 bits (104), Expect = 0.002
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLT--GARRGLH-KHLLLVD 371
L K+ W+HG ++R+ AE L+ ++ +LVR+S + L+ +H K D
Sbjct: 216 LEKQVWYHGALTRSEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMKFSQSRD 275
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
++ FDS+P +I ++ +N+LPI A+ LL PVL
Sbjct: 276 GKFILGENSPPFDSIPEVIHFYTTNKLPIRGAEHLSLL-FPVL 317
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 46.0 bits (104), Expect = 0.002
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
+ ++PW+ G ISR AE L++ +GEFLVR+S + G ++ +KH + + G
Sbjct: 296 MEQQPWYFGRISRERAEDLLLHGREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVDG 355
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+++ +R F + LI ++ ++ PI S+ + L
Sbjct: 356 LLKIGNRTFVDMNALINHYTTS--PIFSSPTEKL 387
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L ++PWFH ++R+ AE+L+ +G FLVR S C F LT + + + G
Sbjct: 50 LEEQPWFHPSLTRSEAEELIRNEPEGSFLVRPSETCPNDFSLTIKHKTFLHMKITRNNAG 109
Query: 375 --VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
++ + + SV +I ++ +P++ A S + L PV +
Sbjct: 110 QFILGEYSQPYSSVSQMIYHYARTLVPVLGAYS-VTLTHPVFK 151
>UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 253
Score = 45.2 bits (102), Expect = 0.003
Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 322 WFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR-- 377
W+HG +SR AE + + FLVR+S + ++ + H+++ GV
Sbjct: 154 WYHGSVSRQQAEAQLQRCREASFLVRDSESGTSKYSIALKTSQSCVHIIVAQTKGVKGLG 213
Query: 378 -TKDR---VFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
T D+ VF S+P L+ ++C++ LP A+ + L+ PV
Sbjct: 214 FTLDQSSCVFPSIPELVHHYCTHRLPFTGAEH-MTLQHPV 252
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 45.2 bits (102), Expect = 0.003
Identities = 27/49 (55%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
AE A L A PWFHG I R AE L+ EDG FLVREST G + L
Sbjct: 367 AEVNAKLNAM-PWFHGRIKREEAENLLKPREDGLFLVRESTNFPGDYTL 414
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 45.2 bits (102), Expect = 0.003
Identities = 21/39 (53%), Positives = 28/39 (71%), Gaps = 3/39 (7%)
Query: 322 WFHGPISRTTAEKLV---VEDGEFLVRESTACAGQFVLT 357
W+HG +SR A++L+ EDG FLVRES+ AG FVL+
Sbjct: 10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLS 48
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 45.2 bits (102), Expect = 0.003
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,
isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG9098-PA, isoform A - Apis mellifera
Length = 797
Score = 44.8 bits (101), Expect = 0.004
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 317 LAKEPWFHGPI---SRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---- 369
L W+HG R AE V DG+FLVR+ + G +VLT +G H ++
Sbjct: 143 LRSHAWYHGSTLRGGRKGAEAEVPNDGDFLVRDCASQPGNYVLTVRWKGQPLHFVINRVV 202
Query: 370 VDPIGV-----VRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ P V + +D FD+V LI ++ + PI A A ++
Sbjct: 203 IQPETVYERAQYQFEDEAFDTVADLITFYVGSGRPISQASGARII 247
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 44.8 bits (101), Expect = 0.004
Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 319 KEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD-PIGV 375
+ W+ GP+SR A+ + + G FLVR+S+ C G +VL+ + H ++ P
Sbjct: 11 RSAWYFGPVSRHEAQNRLQGQKHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKR 70
Query: 376 VRTKDRVFDSVPHLIKYH 393
+ DR F+ +P L++++
Sbjct: 71 FKIGDREFEHLPALLEFY 88
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 44.4 bits (100), Expect = 0.006
Identities = 23/49 (46%), Positives = 30/49 (61%), Gaps = 4/49 (8%)
Query: 322 WFHGPISRTTAEKLVVEDGE----FLVRESTACAGQFVLTGARRGLHKH 366
WFHG +SR AE L++EDG FLVRES++ G +VL+ G H
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAH 57
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 44.4 bits (100), Expect = 0.006
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 321 PWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
PW+HG + R E ++ G +LVR+ST G +VL+ + G H ++ + +
Sbjct: 8 PWYHGVLKRVETEGILNGKPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67
Query: 379 KDRVFDSVPHLIKYH 393
D+ F +P +I+++
Sbjct: 68 GDQTFPDLPSIIEFY 82
>UniRef50_UPI0000E25482 Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 457
Score = 44.0 bits (99), Expect = 0.007
Identities = 17/28 (60%), Positives = 21/28 (75%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVR 32
GSF+ KPA GWLHPD+ + GV+Y VR
Sbjct: 52 GSFIHKPAHGWLHPDARVLGPGVSYVVR 79
>UniRef50_UPI00003AFA59 Cluster: PREDICTED: Gallus gallus similar to
SHC (Src homology 2 domain containing) transforming
protein 1 (LOC430685), partial mRNA.; n=1; Gallus
gallus|Rep: PREDICTED: Gallus gallus similar to SHC (Src
homology 2 domain containing) transforming protein 1
(LOC430685), partial mRNA. - Gallus gallus
Length = 191
Score = 44.0 bits (99), Expect = 0.007
Identities = 18/28 (64%), Positives = 20/28 (71%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVR 32
GSFV KP RGWLHPD + GV+Y VR
Sbjct: 164 GSFVNKPTRGWLHPDDKVMGPGVSYHVR 191
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 44.0 bits (99), Expect = 0.007
Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 321 PWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRGLHKHLLLV-DPIGV 375
PW++G I+R AEKL++ +DG FLVR S + + ++ ++ G H + IG
Sbjct: 249 PWYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGA 308
Query: 376 VRTKDRV-FDSVPHLIKYHCSN 396
DR+ F ++ LI Y+ N
Sbjct: 309 YFVSDRISFATLGELISYYQRN 330
>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA
- Drosophila melanogaster (Fruit fly)
Length = 1236
Score = 44.0 bits (99), Expect = 0.007
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 14/106 (13%)
Query: 320 EPWFHGPIS--RTTAEKLVVE-----DGEFLVRESTACAGQFVLTGARRGLHKH--LLLV 370
E WFHG + R A+ L+ + DG FLVRES G + L+ RR H + L
Sbjct: 587 ENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLK 646
Query: 371 DPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
G ++ ++ VFDS+ LI Y+ N L S++ +++L++PV
Sbjct: 647 HENGSIKYYLVENFVFDSLYSLIVYYRKNMLR--SSEFSIILKEPV 690
>UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 533
Score = 44.0 bits (99), Expect = 0.007
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 318 AKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLL---LVDP 372
A PWFHG ISR +E L+ G FLVR S G V +R G KH L + +
Sbjct: 391 APAPWFHGIISRDQSEVLLTHKPTGSFLVRVSERIWGYTVSYASRDGSFKHFLVEKIKEG 450
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
+ T V D + L+ YH
Sbjct: 451 YQFLGTNQVVHDELFDLVAYH 471
>UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG16480;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG16480 - Caenorhabditis
briggsae
Length = 487
Score = 44.0 bits (99), Expect = 0.007
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 9/98 (9%)
Query: 319 KEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQ---FVLT-----GARRGLHKHLLLV 370
++PWFHG + R + L++++G+FLVR S +GQ +L+ ++ +H +
Sbjct: 64 EQPWFHGLLPREEVQLLLLKNGDFLVRMSEPSSGQARHLILSVMQNESSQEAMHYVIRNA 123
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
D + K+ FDS+ LI +H N+L + S L+
Sbjct: 124 DGKFSITGKEN-FDSLIELINHHKQNKLHEDNPKSVLI 160
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 43.6 bits (98), Expect = 0.010
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRG-LHKHLLLVDPI 373
L K W+HG ISR AE L+ +G FLVRES + GQ ++ G ++ + + D
Sbjct: 170 LEKHSWYHGRISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSD 229
Query: 374 G-VVRTKDRVFDSVPHLIKYH 393
G + T + +F+++ L+ +H
Sbjct: 230 GKMYVTTESIFNTLAELVHHH 250
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 43.6 bits (98), Expect = 0.010
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAE-KLVVED--GEFLVRESTACAGQFVLTG-ARRGLH 364
T +A + W+HG + R +AE +L D G +LVRES G +VL+ +RG++
Sbjct: 55 TVDANLTAPPENEWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGIN 114
Query: 365 KHLLLVDPIGVVRTKDRVFDSVPHLIKY--HCSNEL 398
H + G R F ++P LI Y H SN L
Sbjct: 115 -HFRVTAVCGDFYVGGRQFQTLPELIGYYTHISNIL 149
>UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound
protein 7 (GRB7 adapter protein) (Epidermal growth
factor receptor GRB-7) (B47).; n=1; Takifugu
rubripes|Rep: Growth factor receptor-bound protein 7
(GRB7 adapter protein) (Epidermal growth factor receptor
GRB-7) (B47). - Takifugu rubripes
Length = 485
Score = 43.6 bits (98), Expect = 0.010
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 4/60 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
A+ +PWFHG +SR A++L+ + DG FL+RES FVL+ + + KH L++
Sbjct: 377 AVHVSQPWFHGGVSRKEAQRLIEKQGLVDGMFLIRESQQHGQCFVLSLSHQLKIKHYLVI 436
>UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep:
Zgc:109892 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 214
Score = 43.6 bits (98), Expect = 0.010
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 322 WFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVVRT 378
WF G ISR AE + +E G FL+RES + G+F ++ + +H +L D +G
Sbjct: 60 WFVGGISRQAAENRLRPLECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFI 119
Query: 379 KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKP 412
D VF S+ L+ ++ N ++ + + LR P
Sbjct: 120 WDEVFSSLNQLVDFYRINS---IAKERTVFLRDP 150
>UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep:
Zgc:158798 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 391
Score = 43.6 bits (98), Expect = 0.010
Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLT--GARRGLH-KHLLLVD 371
L K+ W+HG +SR+ AE L+ ++ +LVR S + L+ + +H K D
Sbjct: 286 LEKQVWYHGSLSRSEAESLLTLCKECSYLVRNSETSRLDYSLSLRSCQGFMHMKFSQCKD 345
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
++ F+++P +I Y+ +++LPI A+ LL PVL
Sbjct: 346 GRYILGQNSPPFETIPEVIHYYTTHKLPIKGAEHLSLL-FPVL 387
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 43.6 bits (98), Expect = 0.010
Identities = 22/38 (57%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Query: 321 PWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
PWFHG I+R AE L+ EDG FLVREST G + L
Sbjct: 478 PWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTL 515
>UniRef50_A7RZG4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 43.6 bits (98), Expect = 0.010
Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 97 NVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACY 156
+V L++S I ++ HDM VS+ + D + AY+AK A + C+
Sbjct: 295 SVILSISVNGIKFIDARSRLLVSHHDMKNVSYITQDPEDKCVF-AYIAKDAK-IDKHYCH 352
Query: 157 VLECGGR-LAQDVIATIGQAFELRFKEFLTKPSTLN 191
V + L+ +V +IGQAFEL +++F+ LN
Sbjct: 353 VFRVEKKELSDEVTMSIGQAFELAYEQFMHLQRHLN 388
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 43.6 bits (98), Expect = 0.010
Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLT 357
E WFHG +S AEKL++E +G FLVRES + G FVL+
Sbjct: 109 ERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLS 149
Score = 39.5 bits (88), Expect = 0.16
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 6/103 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPI 373
++ WFH IS AEKL+ E DG FL R S++ G F L+ RRG + +
Sbjct: 1 MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLS-VRRGNEVTHIKIQNN 59
Query: 374 G--VVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVL 414
G F ++P L++Y+ N A+ L++P++
Sbjct: 60 GDFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLI 102
>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4200-PA - Tribolium castaneum
Length = 1233
Score = 43.2 bits (97), Expect = 0.013
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 14/106 (13%)
Query: 320 EPWFHGPIS--RTTAEKLV-----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDP 372
E WFHG ++ R AE+L+ + DG FLVR S G++ L+ R G H +
Sbjct: 573 EKWFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSK 632
Query: 373 IGVVRTK-----DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
T+ + FDS+ LI ++ P+V+A+ ++ L++PV
Sbjct: 633 PDKQHTRYYLTDAKYFDSLYSLITHY--RNCPLVTAEFSITLQEPV 676
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 42.7 bits (96), Expect = 0.017
Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Query: 322 WFHGPISRTTAEKL--VVEDGEFLVR--ESTACAGQFVLTGARRGLH-KHLLLVDPIGVV 376
WFHGP++R AE L + ++G +LVR E++ L ++ LH K + V+
Sbjct: 121 WFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVVL 180
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
F SVP L+ ++ S LP+ A+ LL
Sbjct: 181 GQHSGPFPSVPELVLHYSSRPLPVQGAEHLALL 213
>UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth factor
receptor bound protein 14; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to growth factor receptor bound
protein 14 - Tribolium castaneum
Length = 655
Score = 42.7 bits (96), Expect = 0.017
Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 7/61 (11%)
Query: 320 EPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRG--LHKHLL-LVDP 372
+PWFH +SR A LV + DG FLVRES + G FVLT G LH + ++DP
Sbjct: 531 QPWFHSGMSRDQATALVTKHGTVDGVFLVRESRSNPGAFVLTYKCGGKVLHAQITPILDP 590
Query: 373 I 373
+
Sbjct: 591 V 591
>UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04880 protein - Schistosoma
japonicum (Blood fluke)
Length = 243
Score = 42.7 bits (96), Expect = 0.017
Identities = 22/86 (25%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLVVED--GEFLVRESTACAGQFVLTGARRGLHKHLLLVD 371
A ++ PW+ G ISR A +++++ G FL+R+ST +G + + ++LL
Sbjct: 1 AEIVPDAPWYFGEISREKANEILIDQPVGTFLIRDSTTKSGYVLAIKEANEVKRYLLTWS 60
Query: 372 P-IGVVRTKDRVFDSVPHLIKYHCSN 396
P + + + ++ S+ L++ H S+
Sbjct: 61 PQLKKFKFGETLYSSLDELVRLHTSH 86
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 42.7 bits (96), Expect = 0.017
Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 7/100 (7%)
Query: 322 WFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
W+HG +SR AE L++ EDG +L+R S G++ L+ + KH + +
Sbjct: 14 WYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQYQF 73
Query: 379 KDRVFDSVPHLIKYHCSNELPIVSADSALL--LRKPVLRS 416
VF S+ ++ H +N+ P++ +S +L LR P R+
Sbjct: 74 GMGVFQSLQEFVE-HFANQ-PLIGGESGILTALRHPYSRN 111
>UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 642
Score = 42.7 bits (96), Expect = 0.017
Identities = 34/87 (39%), Positives = 42/87 (48%), Gaps = 10/87 (11%)
Query: 317 LAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDP 372
LA+E WFHG IS A L+ EDG FLVRES + + +VLT H LV
Sbjct: 529 LAEEFWFHGRISHDEALVLMKREGFEDGLFLVRESCSVSDVYVLTFCMNKKVFHCQLVQD 588
Query: 373 IG------VVRTKDRVFDSVPHLIKYH 393
IG K F S+ LI+Y+
Sbjct: 589 IGPGSKMYYRLDKGPAFPSILELIRYY 615
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 42.7 bits (96), Expect = 0.017
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 374 LEKHSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQ 412
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 3/39 (7%)
Query: 322 WFHGPISRTTAEKLVVED---GEFLVRESTACAGQFVLT 357
WFHG ISR AE+++ ++ G F+VREST+ G FVL+
Sbjct: 9 WFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLS 47
>UniRef50_Q8NFT0 Cluster: Src homology 2 domain-containing
transforming protein 1 isoform p52; n=10; Amniota|Rep:
Src homology 2 domain-containing transforming protein 1
isoform p52 - Homo sapiens (Human)
Length = 55
Score = 42.3 bits (95), Expect = 0.023
Identities = 17/28 (60%), Positives = 20/28 (71%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVR 32
GSFV KP RGWLHP+ + GV+Y VR
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVR 55
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 461 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 499
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 111 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 149
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 8 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 46
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 71 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 109
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 42.3 bits (95), Expect = 0.023
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 122 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 160
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 41.9 bits (94), Expect = 0.030
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 322 WFHGPISRTTAEKLVVED---GEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
W+HG + R TAE+ + + G +LVRES G +VL+ R H + G
Sbjct: 77 WYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 136
Query: 379 KDRVFDSVPHLIKY--HCSNEL 398
R F+S+ L+ Y HCS+ L
Sbjct: 137 GGRQFNSLMDLVAYYTHCSDLL 158
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 41.9 bits (94), Expect = 0.030
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 319 KEPWFHGPISRTTAEKLVVED--GEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
K W G I+R+ + L+++ G FLVR+S C G VL + H ++
Sbjct: 15 KHLWHFGGITRSETDNLLIQKRPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQF 74
Query: 377 RTKDRVFDSVPHLIKYH 393
D++F ++P ++ ++
Sbjct: 75 VIGDQIFSTLPDILNFY 91
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 41.9 bits (94), Expect = 0.030
Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 4/40 (10%)
Query: 322 WFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT 357
W+HG +SR E L+ E DG FLVRES + G FVL+
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLS 48
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 41.9 bits (94), Expect = 0.030
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Query: 317 LAKEPWFHGPISRTTAE-KLVVED-GEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPI 373
L WF G ISR AE +L D G FLVRES + G+F ++ + +H +L D
Sbjct: 55 LRPHAWFAGRISRHVAENRLHQRDCGSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDRE 114
Query: 374 GVVRTKDRVFDSVPHLIKYHCSNEL 398
G + +F S+ L+ Y+ +N +
Sbjct: 115 GYYFVWEEIFPSLNQLVDYYKTNSI 139
>UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF12132, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 422
Score = 41.9 bits (94), Expect = 0.030
Identities = 24/50 (48%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
Query: 321 PWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARRGLHK 365
PWFHGPISR A LV G FLVR+S G +VLT +G K
Sbjct: 134 PWFHGPISRVKAAHLVQSSGPEGHGVFLVRQSETRRGDYVLTFNYQGKAK 183
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 41.9 bits (94), Expect = 0.030
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 41.9 bits (94), Expect = 0.030
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 320 EPWFHGPIS--RTTAEKLVVE-----DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDP 372
E WFHG + R AE L+ E DG FLVRES G F L+ R+ H +
Sbjct: 558 EKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSK 617
Query: 373 IGVVRTK-----DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSSS 418
+TK + FDS+ LI ++ + P+ S D +L++PV + S
Sbjct: 618 QERGQTKYYLIDNLAFDSLYSLITHY--QKYPLRSQDFQQILKEPVPQPQS 666
Score = 41.9 bits (94), Expect = 0.030
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 320 EPWFHGPISRTTAE---KLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
+PW+H + RT AE K + DG FLVR++ + ++ G KH ++ +
Sbjct: 670 KPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLF 729
Query: 377 RTKDRVFDSVPHLIKYH 393
+ F+S+ L+ Y+
Sbjct: 730 TIGNAQFESLVELVNYY 746
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 41.9 bits (94), Expect = 0.030
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 307 PLT--AEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT--G 358
P+T A+A L+ +PW+ +SRT A++L++ E G FL+R S + G + L+
Sbjct: 103 PITHVAKASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRA 162
Query: 359 ARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCSN 396
+ H + + + K R+F + L+ Y+ +N
Sbjct: 163 QAKVCHYRVSMAADGSLYLQKGRLFPGLEELLTYYKAN 200
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 41.9 bits (94), Expect = 0.030
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGA-RRGLHKHLLLVDPIGVV 376
PW+H ISR AE+L+ DG FLVR+S + G + L +R +H + +L D G++
Sbjct: 5 PWYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYALCLLFQRHVHTYRILPDADGLL 64
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 41.9 bits (94), Expect = 0.030
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 3.5
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 41.9 bits (94), Expect = 0.030
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>UniRef50_UPI0000D56ADB Cluster: PREDICTED: similar to CG11804-PC,
isoform C; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11804-PC, isoform C - Tribolium castaneum
Length = 429
Score = 41.5 bits (93), Expect = 0.040
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 34/178 (19%)
Query: 13 RGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSAD 72
R W+HP L + Y V+++G V D +V KE I + LR
Sbjct: 27 RKWIHPPEALQKGHIAYLVKFLGNTVV-------DQPKGIEVVKEGIRK------LRFTQ 73
Query: 73 KKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMP--RVSFAS 130
+ R+ S+ A+ V LT+S + A+ E + H P R+S+ +
Sbjct: 74 QLRK-SETGAKT-----------RKVELTISIDGV--AIQEPRTHVILHQFPLHRISYCA 119
Query: 131 GGDADSLDYVAYVAKSAPPTEWRACYVLEC----GGRLAQDVIATIGQAFELRFKEFL 184
D + +++AK + A EC +LA+++ TIGQAFEL +K FL
Sbjct: 120 D-DKGEKKFFSFIAKQPNQVDNDAEEKHECFVFISDKLAEEITLTIGQAFELAYKRFL 176
>UniRef50_Q9VC09 Cluster: CG11168-PA; n=3; Sophophora|Rep:
CG11168-PA - Drosophila melanogaster (Fruit fly)
Length = 863
Score = 41.5 bits (93), Expect = 0.040
Identities = 42/178 (23%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Query: 15 WLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLD--FDTRSQVAKECIARVCAAAGLRSAD 72
W H + Y++ Y+G T ++KL TR + K I +A S
Sbjct: 690 WCHSPYTFIYGEIRYSLFYLGS----TVIRKLQGTLSTRKSIQKLKIDENLKSAASVSDF 745
Query: 73 KKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGG 132
+ + L A + NV + VS + + I HD+ ++
Sbjct: 746 SLLENCTTSTKYLKAANHQTR--LNVDIAVSCVGVKFIDHDKKTAICCHDIENINCVCQ- 802
Query: 133 DADSLDYVAYVAKSAPPTEWRACYVLECGG-RLAQDVIATIGQAFELRFKEFLTKPST 189
D++ L Y AY+ K + C+V LA+++I T+GQAFE+ ++ L++ T
Sbjct: 803 DSEDLRYFAYITKEQ---DLHYCHVFMVDSLELAKEIIMTLGQAFEVAYQLALSRQGT 857
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 41.5 bits (93), Expect = 0.040
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Query: 319 KEPWFHGPISRTTAE---KLVVEDGEFLVRESTACAGQFVL-TGARRGLHKHLLLVDPIG 374
++PWFHG I RT AE K + E G FL+RE + G +V+ + G++ +L + G
Sbjct: 158 QQPWFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESNNQG 217
Query: 375 VVRTKD-RVFDSVPHLIKYH 393
+ K R FD++ ++ ++
Sbjct: 218 QLSIKSGRSFDNLMAVVNFY 237
Score = 36.7 bits (81), Expect = 1.1
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 322 WFHGPISRTTAEKLV-----VEDGEFLVRESTACAGQFVLTGAR-RGLHKHLLLVDPIGV 375
WFHG I+R AE + ++DG +L+RES + G +VL+ + + + + + P G+
Sbjct: 9 WFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQRQPSGM 68
Query: 376 VRTKD-RVFDSVPHLIKYH 393
V D F L+ +H
Sbjct: 69 VGIADGPQFPGPVELVNHH 87
>UniRef50_UPI000065D045 Cluster: cajalin 2 isoform a; n=1; Takifugu
rubripes|Rep: cajalin 2 isoform a - Takifugu rubripes
Length = 1026
Score = 41.1 bits (92), Expect = 0.053
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K + C+V
Sbjct: 907 IVLSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSSH-HYCHV 964
Query: 158 LECGG-RLAQDVIATIGQAFELRFKEFLTKPSTLNLNGSLP 197
LA ++I T+GQAFE+ ++ L + + + +LP
Sbjct: 965 FTAFDVNLAYEIILTLGQAFEVAYQLALQARKSGHGSSTLP 1005
>UniRef50_Q4RGC9 Cluster: Chromosome 19 SCAF15103, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 19 SCAF15103, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 376
Score = 41.1 bits (92), Expect = 0.053
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K + C+V
Sbjct: 252 IVLSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSSH-HYCHV 309
Query: 158 LECGG-RLAQDVIATIGQAFELRFKEFLTKPSTLNLNGSLP 197
LA ++I T+GQAFE+ ++ L + + + +LP
Sbjct: 310 FTAFDVNLAYEIILTLGQAFEVAYQLALQARKSGHGSSTLP 350
>UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1;
Schistosoma mansoni|Rep: Fes-like tyrosine kinase
protein - Schistosoma mansoni (Blood fluke)
Length = 1259
Score = 41.1 bits (92), Expect = 0.053
Identities = 15/30 (50%), Positives = 22/30 (73%)
Query: 319 KEPWFHGPISRTTAEKLVVEDGEFLVREST 348
KEPWFHG + R E+L+ G+FLVR+++
Sbjct: 818 KEPWFHGVLPRAEVERLLQNQGDFLVRQTS 847
>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1 - Homo sapiens (Human)
Length = 1290
Score = 41.1 bits (92), Expect = 0.053
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 652
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 653 LSEPVPQTNA 662
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 40.7 bits (91), Expect = 0.070
Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 4/49 (8%)
Query: 322 WFHGPISRTTAEKLVVEDGE----FLVRESTACAGQFVLTGARRGLHKH 366
WFHG I+R TA ++ +G FLVREST+ +G +V++ GL +H
Sbjct: 76 WFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGLPQH 124
>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor Grb2 -
Strongylocentrotus purpuratus
Length = 241
Score = 40.7 bits (91), Expect = 0.070
Identities = 34/111 (30%), Positives = 50/111 (45%), Gaps = 9/111 (8%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV---EDGEFLVR--ESTACAGQFVLTGARRG 362
L E + PW+ G ISR AE+ ++ DG F++R ES +G F L+ R
Sbjct: 48 LVPENYLKIEKSHPWYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRD 107
Query: 363 LHKHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKP 412
+H +L D G F S+ L+ YH N VS ++L +P
Sbjct: 108 QVQHFKILTDLAGKYFLWVVKFTSINDLVDYHKDNS---VSRTQEIVLNEP 155
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 40.7 bits (91), Expect = 0.070
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 322 WFHGPISRTTAEKLV---VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
WFHG I+R +EK++ E G FL+RES G F ++ KH +
Sbjct: 291 WFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKKFCI 350
Query: 379 KDRVFDSVPHLIKYHCSNELPIVSADSALL 408
R F+S+ L+ ++ PI S+D L
Sbjct: 351 GQRKFESLDDLVDHY--KRSPIFSSDDGEL 378
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 40.7 bits (91), Expect = 0.070
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 9/83 (10%)
Query: 319 KEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVL-----TGARRGLHKHLLLV 370
+ W+ GP+SR A ++++ E G FLVR+S + AG +VL T + +
Sbjct: 9 RNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQ 68
Query: 371 DPIGVVRTKDRVFDSVPHLIKYH 393
D I V R D+ FD++P L+ ++
Sbjct: 69 DQI-VYRIGDQSFDNLPKLLTFY 90
>UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 636
Score = 40.3 bits (90), Expect = 0.092
Identities = 21/48 (43%), Positives = 29/48 (60%), Gaps = 5/48 (10%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLT 357
A LA PWFHG +SR A +LV+ G F++R+S G++VLT
Sbjct: 404 ASLAGYPWFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLT 451
>UniRef50_Q9VCM6 Cluster: CG4393-PA; n=3; Sophophora|Rep: CG4393-PA -
Drosophila melanogaster (Fruit fly)
Length = 1348
Score = 40.3 bits (90), Expect = 0.092
Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 10/109 (9%)
Query: 94 SGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWR 153
SG+ ++L + + + + TI H++ ++ A D++ L + AY+ K +
Sbjct: 1236 SGSPLSLAICHRGVEFKDVNSKRTICEHEIQNINCACQ-DSEDLRHFAYITKEQ---DLH 1291
Query: 154 ACYV-LECGGRLAQDVIATIGQAFELRFKEFL-----TKPSTLNLNGSL 196
C+V L LA ++I T+GQAFE+ ++ L T P L NG L
Sbjct: 1292 YCHVFLVESTDLASEIILTLGQAFEVAYQLALRDGITTTPELLLDNGML 1340
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 40.3 bits (90), Expect = 0.092
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 319 KEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-----V 370
+ W+ G +SR A L++ E G FLVR+ST G FVL H ++
Sbjct: 9 RSSWYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPSG 68
Query: 371 DPIGVVRTKDRVFDSVPHLIKYH 393
D V R D+ F +P L+ ++
Sbjct: 69 DECFVYRIGDQTFADLPDLLSFY 91
>UniRef50_UPI0000F2C764 Cluster: PREDICTED: similar to
SH2-containing protein Nsp1; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to SH2-containing
protein Nsp1 - Monodelphis domestica
Length = 741
Score = 39.9 bits (89), Expect = 0.12
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 15/113 (13%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTAC----AGQFVLTGARRGLHKHLLLV-- 370
L + W+HG +S+ AE L+++DG+FLV S + + VL+ G H +V
Sbjct: 73 LVDQTWYHGRLSQKEAEALLLKDGDFLVWASPSTLVLDSSPLVLSCCWGGQPLHFDVVRI 132
Query: 371 --------DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
+ + +D F S+P L+K + + + P+ A A+ R PV R
Sbjct: 133 QLRPRPGRPSRALFQLEDERFPSLPALVKCYVATQRPLSQASGAVASR-PVAR 184
>UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound
protein 14 (GRB14 adapter protein).; n=5; Tetrapoda|Rep:
Growth factor receptor-bound protein 14 (GRB14 adapter
protein). - Xenopus tropicalis
Length = 428
Score = 39.9 bits (89), Expect = 0.12
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
A+ +PWFH +SR A+KL+++ DG F++R+S + FVL+ KH +V
Sbjct: 320 AVHISQPWFHHQLSRDEAQKLILQQGLVDGVFILRDSQSTHKAFVLSMCHGQKVKHFQIV 379
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 39.9 bits (89), Expect = 0.12
Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 318 AKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
A PW++G ++R AE + E +G+FL+R+S + F ++ +G +KH +
Sbjct: 24 AGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKET 83
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
V R F ++ L++++ + PI +++
Sbjct: 84 VYCIGQRKFSTMEELVEHY--KKAPIFTSE 111
>UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2; n=24; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
- Homo sapiens (Human)
Length = 1258
Score = 39.9 bits (89), Expect = 0.12
Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 315 ALLAKEP-WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGA-RRGLHKHLLL 369
AL ++ P W+H +SR AE+L+ DG FLVR+S + AG F L ++ +H + +L
Sbjct: 13 ALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRIL 72
Query: 370 VD 371
D
Sbjct: 73 PD 74
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 39.9 bits (89), Expect = 0.12
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 181 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 240
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 241 IGGRRFSSLSDLIGYY 256
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 39.9 bits (89), Expect = 0.12
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKH 366
++ +A LL W+HG ++R AE L++ DG +L+R+S G + L+ + KH
Sbjct: 23 SDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ + F S+ +K H +N+ P++ +++ L+
Sbjct: 83 FHVEYTGYSFKFGFNEFSSLKDFVK-HFANQ-PLIGSETGTLM 123
>UniRef50_Q99767 Cluster: Amyloid beta A4 precursor protein-binding
family A member 2; n=26; Euteleostomi|Rep: Amyloid beta
A4 precursor protein-binding family A member 2 - Homo
sapiens (Human)
Length = 749
Score = 39.9 bits (89), Expect = 0.12
Identities = 58/225 (25%), Positives = 99/225 (44%), Gaps = 28/225 (12%)
Query: 1 MAESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIA 60
+A SFVA P G P+ ++ DG+ +A Y+G ++L S + + R A+E ++
Sbjct: 348 VASFPSFVAVP--GPCEPEDLI--DGIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVS 402
Query: 61 RVCAAAGLRSADKKRRVSQAAARALT------ARPRMSHSGANVALTVSSKAI-TLA-VL 112
RV KK S+ A+ LT + R+ A+ T+ A+ T++ +
Sbjct: 403 RVKRMQKAAKIKKKAN-SEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIA 461
Query: 113 EGGDTI---ARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVI 169
+ G+ + AR MPR D ++ A+ C+V E AQ +
Sbjct: 462 DIGNIVVLMARRRMPR-----SASQDCIETTPG-AQEGKKQYKMICHVFESED--AQLIA 513
Query: 170 ATIGQAFELRFKEFLTKPSTLNLNGSLPSCESACGLVEDREYYND 214
+IGQAF + ++EFL +N S + ++ +E YND
Sbjct: 514 QSIGQAFSVAYQEFL---RANGINPEDLSQKEYSDIINTQEMYND 555
>UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adaptor
protein 2, partial; n=1; Pan troglodytes|Rep: PREDICTED:
similar to SH2B adaptor protein 2, partial - Pan
troglodytes
Length = 178
Score = 39.5 bits (88), Expect = 0.16
Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 6/53 (11%)
Query: 311 EAQAAL-LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLT 357
EA+ L L+ PWFHG +SR A +LV+ G F++R+S G++VLT
Sbjct: 118 EAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLT 170
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 39.5 bits (88), Expect = 0.16
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRG-LHKHLLLVDPI 373
L K W+HG I R AE L+ +G FLVRES + GQ ++ G ++ + + D
Sbjct: 169 LEKHSWYHGRICRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSE 228
Query: 374 G-VVRTKDRVFDSVPHLIKYH 393
G + T + F+++ L+ +H
Sbjct: 229 GKMFVTTESKFNTLAELVHHH 249
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 39.5 bits (88), Expect = 0.16
Identities = 20/41 (48%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG ++ AEKL+ E G+ FLVRES + G FVL+
Sbjct: 108 ERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLS 148
>UniRef50_Q4S5P0 Cluster: Chromosome 9 SCAF14729, whole genome shotgun
sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 9
SCAF14729, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1063
Score = 39.5 bits (88), Expect = 0.16
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 910 IVLSITYKGVKFIDAANKNIIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 967
Query: 158 LECGG-RLAQDVIATIGQAFELRFKEFLTKPSTLNLNGSLPSCE 200
L ++I T+GQAFE+ ++ L T + +LPS E
Sbjct: 968 FSTVDVNLTYEIILTLGQAFEVAYQLALQAQRT-KQHQNLPSSE 1010
>UniRef50_Q8TAP3 Cluster: Ankyrin repeat and sterile alpha motif
domain containing 1B; n=7; Eutheria|Rep: Ankyrin repeat
and sterile alpha motif domain containing 1B - Homo
sapiens (Human)
Length = 510
Score = 39.5 bits (88), Expect = 0.16
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 355 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 412
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 413 FTAFDVNLAYEIILTLGQAFEVAYQ 437
>UniRef50_Q7Z6G8 Cluster: Ankyrin repeat and sterile alpha motif
domain-containing protein 1B; n=45; Euteleostomi|Rep:
Ankyrin repeat and sterile alpha motif domain-containing
protein 1B - Homo sapiens (Human)
Length = 1249
Score = 39.5 bits (88), Expect = 0.16
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 1106 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 1163
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 1164 FTAFDVNLAYEIILTLGQAFEVAYQ 1188
>UniRef50_Q7Z6G6 Cluster: AIDA-1bDAnk; n=15; Euarchontoglires|Rep:
AIDA-1bDAnk - Homo sapiens (Human)
Length = 750
Score = 39.5 bits (88), Expect = 0.16
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 607 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 664
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 665 FTAFDVNLAYEIILTLGQAFEVAYQ 689
>UniRef50_A7E259 Cluster: ANKS1B protein; n=7; Eutheria|Rep: ANKS1B
protein - Homo sapiens (Human)
Length = 450
Score = 39.5 bits (88), Expect = 0.16
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 295 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 352
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 353 FTAFDVNLAYEIILTLGQAFEVAYQ 377
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 39.5 bits (88), Expect = 0.16
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HG ISR+ +E ++ G FLVRES GQ+ ++ G H + + +
Sbjct: 189 LDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNT 248
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
+ T++ F ++ L+ +H
Sbjct: 249 EKMFITQEVKFRTLGELVHHH 269
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 39.1 bits (87), Expect = 0.21
Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 319 KEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL--VDPI 373
K W+ G +SR A L++ E G FLVR+S + G FVL H ++ +
Sbjct: 10 KSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQG 69
Query: 374 GVVRTK--DRVFDSVPHLIKYH 393
+R + D++F +P+L+ ++
Sbjct: 70 DQIRYRIGDQIFPDIPNLLAFY 91
>UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 21
SCAF14577, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 608
Score = 39.1 bits (87), Expect = 0.21
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG I R A K++++ DG FL+R+S + FVLT KH +
Sbjct: 499 AAIHRTQVWFHGRIVREEAHKMIIQQGQVDGLFLLRDSQSNPRAFVLTLCHHQKIKHFQI 558
Query: 370 V 370
+
Sbjct: 559 L 559
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 39.1 bits (87), Expect = 0.21
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 4/64 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGA-RRGLHKHLLLVDP 372
+A W+H ISR AE+L+ +DG +LVR+S + G + L +R +H + +L D
Sbjct: 9 MATAVWYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYALCLLFQRHVHTYRILPDA 68
Query: 373 IGVV 376
G++
Sbjct: 69 DGLL 72
>UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 419
Score = 39.1 bits (87), Expect = 0.21
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 5/96 (5%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTAC---AGQFVLTGARRGLHKHLLLVD-PIGVVR 377
W+HG + R L+ DG+FLVR S + + VL+ +G H L + G +
Sbjct: 32 WYHGLLPRADINTLLENDGDFLVRTSHIVGQDSAKTVLSVKWKGKCHHWQLQEKEDGSIV 91
Query: 378 TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
++R F+SV ++ LP VSA+ LL P+
Sbjct: 92 IEERKFESVLDMVTTLRMKRLP-VSANCPALLLNPI 126
>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein plc-3 - Caenorhabditis elegans
Length = 1299
Score = 39.1 bits (87), Expect = 0.21
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 320 EPWFHGPISRTTAEKL---VVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
+PWF + AE+L V EDG FL+R S+ + +VL+ G H L +
Sbjct: 662 QPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIF 721
Query: 377 RTKDRVFDSVPHLIKYHCSNE 397
+VF+++ +++++ + E
Sbjct: 722 VVNQKVFENLNQIVEFYANRE 742
Score = 34.3 bits (75), Expect = 6.0
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 320 EPWFHGPISRTTAEKLVVE-----DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
E WFHG R A+K ++E +G F++R+S G F L+ G H+ + I
Sbjct: 552 EEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKII 611
Query: 375 VVRTK-----DRVFDSVPHLIKYHCSNEL 398
K ++V D++ L+ Y+ + L
Sbjct: 612 DKEKKYYFMDNKVCDTLYELVSYYTRHYL 640
>UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein kin-14 - Caenorhabditis elegans
Length = 418
Score = 39.1 bits (87), Expect = 0.21
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Query: 322 WFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDPIGVVRTK 379
WFHG + R A++L+V+ G FL+R S ++ R LH + D +
Sbjct: 30 WFHGVLQRQDADELLVKPGSFLLRASEVHGKMSMILSVRHDGKLHNIAVNSDTGENFWFE 89
Query: 380 DRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
S+ L+++H + PI S + L+ P+
Sbjct: 90 GHREKSIDQLVQWHMTTSTPITKT-SGVKLKYPI 122
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 39.1 bits (87), Expect = 0.21
Identities = 22/48 (45%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Query: 311 EAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
+ +A L + PWF G I+R AE+L+ E G FLVREST G + L
Sbjct: 81 QRRALHLHEMPWFFGKITREKAEELLTPREVGLFLVRESTNFPGDYTL 128
>UniRef50_A7RG70 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 131
Score = 39.1 bits (87), Expect = 0.21
Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
V L ++ +++ + + + + + +S+ + D + A++AK + CYV
Sbjct: 44 VDLKINIDGVSIEDSKSKEVLHSYPLHHISYCAD-DKRNKRVFAFIAKDKTSPK-HTCYV 101
Query: 158 LECGGRLAQDVIATIGQAFELRFKEFLTK 186
E RLA+++ T+GQAF+L ++ FL +
Sbjct: 102 FEAE-RLAEELTLTVGQAFDLAYRRFLER 129
>UniRef50_Q5RGM2 Cluster: Novel protein containing a phosphotyrosine
interaction domain; n=5; Clupeocephala|Rep: Novel
protein containing a phosphotyrosine interaction domain
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 200
Score = 38.7 bits (86), Expect = 0.28
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 73 KKRRVSQAAARALTARPRMSHSG-ANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASG 131
K ++ AA R + R S V LTVS K I +A E D + + R+S+ +
Sbjct: 74 KGEEMAAAAIRRIVTTARASAKKFRKVTLTVSPKGIIIADTETNDLVEDVSIYRISYCT- 132
Query: 132 GDADSLDYVAYVAKSAPPTEWRACYVLEC-GGRLAQDVIATIGQAFEL 178
D AYV++S E C+ C ++AQ V T+ QAF++
Sbjct: 133 TDKTQDKVFAYVSQS-QFNETLECHAFLCQKKKIAQAVTLTVAQAFKI 179
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 38.7 bits (86), Expect = 0.28
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ + + H ++ G
Sbjct: 185 WYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCGDYY 244
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 245 IGGRRFSSLSDLIGYY 260
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 38.7 bits (86), Expect = 0.28
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 170 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 224
>UniRef50_UPI00015B6225 Cluster: PREDICTED: similar to IP14385p; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to IP14385p -
Nasonia vitripennis
Length = 1357
Score = 38.3 bits (85), Expect = 0.37
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 97 NVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKS-APPTEWRAC 155
++ L++S + + + I H++ + A DAD L + AY+ K A T +
Sbjct: 1107 DITLSISYRGVRFLNTLTDEPICEHEIRNIHCACQ-DADDLTHFAYITKDHASRTHFCHV 1165
Query: 156 YVLECGGRLAQDVIATIGQAFELRFK 181
+ + +A ++I T+GQAFE+ ++
Sbjct: 1166 FCVPTMVNMATEIILTLGQAFEVAYQ 1191
>UniRef50_UPI000065E21B Cluster: Homolog of Homo sapiens "ankyrin
repeat and sterile alpha motif domain containing 1; n=2;
Clupeocephala|Rep: Homolog of Homo sapiens "ankyrin
repeat and sterile alpha motif domain containing 1 -
Takifugu rubripes
Length = 1122
Score = 38.3 bits (85), Expect = 0.37
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 970 IVLSITYKGVKFIDAANKNIIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1027
Query: 158 LECGG-RLAQDVIATIGQAFELRFKEFLTKPSTLNLNGSLPSCE 200
L ++I T+GQAFE+ ++ L T + +LPS +
Sbjct: 1028 FSTVDVNLTYEIILTLGQAFEVAYQLALQAQRT-KQHQNLPSSD 1070
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 38.3 bits (85), Expect = 0.37
Identities = 21/44 (47%), Positives = 26/44 (59%), Gaps = 6/44 (13%)
Query: 320 EPWFHGPISRTTAEKLVVE------DGEFLVRESTACAGQFVLT 357
E W+HG I+R A LV + +G FLVREST G +VLT
Sbjct: 8 ERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLT 51
>UniRef50_Q7JUY7 Cluster: PTB domain-containing adapter protein
ced-6; n=2; Sophophora|Rep: PTB domain-containing
adapter protein ced-6 - Drosophila melanogaster (Fruit
fly)
Length = 517
Score = 38.3 bits (85), Expect = 0.37
Identities = 48/190 (25%), Positives = 74/190 (38%), Gaps = 21/190 (11%)
Query: 13 RGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSAD 72
R WLH L S Y V++ G + V D +V KE I ++ A ++ A+
Sbjct: 73 RNWLHTPEQLISGHAVYLVKFFGNLSV-------DQPKGIEVVKEAIRKLQFAQQMKKAE 125
Query: 73 -------KKRRVSQAAARALTARPRMSHSGANVAL-TVSSKAITLAVLEGGDTIARHDMP 124
KK ++ + PR L +S A V + IA+
Sbjct: 126 TGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAK---- 181
Query: 125 RVSFASGGDADSLDYVAYVAK-SAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
V G D S + SA E C+V +LA D+ TIGQAF+L ++++
Sbjct: 182 TVKTQDGSDPTSNGHANGNGDGSAKVEESHECFVF-ISNKLASDITLTIGQAFDLAYRKY 240
Query: 184 LTKPSTLNLN 193
+ NL+
Sbjct: 241 MDSTEKTNLS 250
>UniRef50_UPI0000E8216F Cluster: PREDICTED: similar to LPAL6438,
partial; n=1; Gallus gallus|Rep: PREDICTED: similar to
LPAL6438, partial - Gallus gallus
Length = 167
Score = 37.9 bits (84), Expect = 0.49
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRE 346
L E +HG ++R AE L+V DG+FLVRE
Sbjct: 138 LRNEDCYHGKLNRKAAESLLVNDGDFLVRE 167
>UniRef50_UPI0000D55DD1 Cluster: PREDICTED: similar to CG4393-PA; n=2;
Coelomata|Rep: PREDICTED: similar to CG4393-PA -
Tribolium castaneum
Length = 1300
Score = 37.9 bits (84), Expect = 0.49
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L++S + + +TI H++ ++ A D+D+ Y AY+ K C+V
Sbjct: 1165 ITLSISYRGVKFINPITKNTICEHEIRNINCACQ-DSDNQSYFAYITKDGDSFY---CHV 1220
Query: 158 LECGGRLAQDVIATIGQAFELRFK 181
E A ++I T+GQAFEL ++
Sbjct: 1221 FESTSS-AIEIILTLGQAFELAYQ 1243
>UniRef50_Q6IRM7 Cluster: MGC83933 protein; n=5; Tetrapoda|Rep:
MGC83933 protein - Xenopus laevis (African clawed frog)
Length = 1084
Score = 37.9 bits (84), Expect = 0.49
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L++S + + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 945 ITLSISYRGVKFIDASNQNEIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1002
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
A ++I T+GQAFE+ ++
Sbjct: 1003 FSTADVNQAYEIILTLGQAFEVAYQ 1027
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 37.9 bits (84), Expect = 0.49
Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 19/111 (17%)
Query: 320 EPWFHGPIS-----RTTAEKLVVE-------DGEFLVRESTACAGQFVLTGARRGLHKHL 367
E WFHG + R AEKL+ E DG FLVRES G + L+ R G +H
Sbjct: 568 ERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHC 627
Query: 368 LL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G R T + VFDS+ LI ++ + P+ + + L PV
Sbjct: 628 RIHSRQESGSTRFYLTDNLVFDSLYRLICHY--RDTPLRCNEFEMRLGNPV 676
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 37.9 bits (84), Expect = 0.49
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRG-LHKHLLLVDPIGVVR- 377
W+HG +SR E L+ G FLVR S + GQ +T G ++ + + D G+
Sbjct: 78 WYHGAVSRQAGEHLLRSGITGSFLVRASESAPGQLSVTVRHLGRVYHYRISQDSRGLFYI 137
Query: 378 TKDRVFDSVPHLIKYH 393
T+ F +V LI++H
Sbjct: 138 TEAHRFPTVVQLIEHH 153
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 37.9 bits (84), Expect = 0.49
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 37.5 bits (83), Expect = 0.65
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 320 EPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
E WFHG I+ AEK +V+ +G +LVRES + G +VL+ H+++
Sbjct: 110 ERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMI 162
Score = 35.5 bits (78), Expect = 2.6
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
+A WFH IS AE+L++ DG FL R S + G F L+ R G H+
Sbjct: 1 MASRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHI 54
>UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;
n=2; Euteleostomi|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 519
Score = 37.5 bits (83), Expect = 0.65
Identities = 20/34 (58%), Positives = 26/34 (76%), Gaps = 2/34 (5%)
Query: 317 LAKEPWFHGPISRTTA-EKLV-VEDGEFLVREST 348
LAK+ W+ GPI+R A EKLV + DG FLVR+S+
Sbjct: 363 LAKQGWYWGPITRWEAEEKLVNLPDGSFLVRDSS 396
>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 222
Score = 37.5 bits (83), Expect = 0.65
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 11/98 (11%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVL-----T 357
P T A+A L E WF ++R E+L++ + G FLVRES G F L T
Sbjct: 89 PSTYVARAQTLQVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDST 148
Query: 358 GARRGLHKH--LLLVDPIGVVRTKDRVFDSVPHLIKYH 393
+ + KH + +D G + F S+ L+KY+
Sbjct: 149 PEQGDVVKHYKIRALDNGGYYISPSTSFSSLQELVKYY 186
>UniRef50_A4TUR6 Cluster: Methyl-accepting chemotaxis protein; n=1;
Magnetospirillum gryphiswaldense|Rep: Methyl-accepting
chemotaxis protein - Magnetospirillum gryphiswaldense
Length = 770
Score = 37.5 bits (83), Expect = 0.65
Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 72 DKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASG 131
D RV A RAL R H+G N ALT KA T AV+ G + +A A G
Sbjct: 709 DPHARVHDAGKRALACHARGDHAGTNAALTDMDKAST-AVMSGLERLAADIQQNAKPAMG 767
Query: 132 G 132
G
Sbjct: 768 G 768
>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
3-kinase regulatory subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 568
Score = 37.5 bits (83), Expect = 0.65
Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 8/111 (7%)
Query: 310 AEAQAALLAKEPWFHGPISRTTA-EKLV-VEDGEFLVRESTACAGQFVLTGARRGLHKHL 367
A+ A L A E W+ G I+R EK+ V DG FLVR++++ G++ LT + G + +
Sbjct: 175 ADTPADLRAAE-WYWGNINRDEVKEKMTDVPDGSFLVRDASSGNGEYTLTLKKDGADRVI 233
Query: 368 LLV---DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
+ D G T+D +SV LI ++ + L + + L P+ R
Sbjct: 234 KIFHTQDKYGF--TRDGSHNSVVDLINFYRNVSLKEYNTILDIKLMYPISR 282
>UniRef50_Q92625 Cluster: Ankyrin repeat and SAM domain-containing
protein 1A; n=32; Euteleostomi|Rep: Ankyrin repeat and
SAM domain-containing protein 1A - Homo sapiens (Human)
Length = 1134
Score = 37.5 bits (83), Expect = 0.65
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 981 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1038
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1039 FSTVDVNLTYEIILTLGQAFEVAYQ 1063
>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to SH2 domain containing 4B - Canis
familiaris
Length = 488
Score = 37.1 bits (82), Expect = 0.86
Identities = 25/56 (44%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 321 PWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
PWFHG ISR AE L+ + +G FLVR S G + ++G KH LVD G
Sbjct: 381 PWFHGIISREDAEDLLENMTEGAFLVRVSEKIWGYTLSYRLQKGF-KH-FLVDASG 434
>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
to Phosphatidylinositol 3-kinase regulatory subunit
alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K) - Apis mellifera
Length = 1256
Score = 37.1 bits (82), Expect = 0.86
Identities = 26/102 (25%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L + W+ G I+R + +++ DG FLVR++++ G++ LT + G +K + + G
Sbjct: 834 LQEAEWYWGDITRDEVNEKMIDSPDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRNG 893
Query: 375 VVRTKDRV-FDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
+ F SV L+ ++ + L ++ + L PV R
Sbjct: 894 KYGFSEPYNFHSVIELVDHYRNCSLAQYNSTLDIKLLYPVSR 935
>UniRef50_A3AC81 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 1370
Score = 37.1 bits (82), Expect = 0.86
Identities = 37/170 (21%), Positives = 67/170 (39%), Gaps = 6/170 (3%)
Query: 51 RSQVAKECIARVCAAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLA 110
R+++A + + + L D K S A+ R ++ R R++ G + +T + K
Sbjct: 528 RTRLASDSAGNILKSMDLADRDNKPSTSSASLRGMSPRRRLASDGISKNITFTEKDDRTM 587
Query: 111 VLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSA--PPTEWRACYVLECGGRLAQDV 168
++A ++ + ADS+ + + P T A L RLA D
Sbjct: 588 P----SSVASQEISTIRRLPSDGADSISKNIDLPEKVTRPATSSAASRGLSPRRRLASDG 643
Query: 169 IATIGQAFELRFKEFLTKPSTLNLNGSLPSCESACGLVEDREYYNDMPDK 218
+ I ++ +L K+ ST L G P + A V+ D +K
Sbjct: 644 VNAISKSIDLADKDTGPARSTAALRGVSPRRQLASDRVDSISKNTDFTEK 693
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 37.1 bits (82), Expect = 0.86
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 322 WFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRGLHKHLLLVDPIGVVRT 378
W++G I+R AEKL+ +G FL+R S + G F L+ G+ +L D G
Sbjct: 34 WYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKFFL 93
Query: 379 KDRVFDSVPHLIKYH 393
F+S+ L+ YH
Sbjct: 94 WVVKFNSLNELVDYH 108
>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
Euteleostomi|Rep: Novel SH2 domain-containing protein -
Homo sapiens (Human)
Length = 431
Score = 37.1 bits (82), Expect = 0.86
Identities = 25/56 (44%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 321 PWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
PWFHG ISR AE L+ + +G FLVR S G + ++G KH LVD G
Sbjct: 324 PWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGF-KH-FLVDASG 377
>UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=27;
Euteleostomi|Rep: Suppressor of cytokine signaling 6 -
Homo sapiens (Human)
Length = 535
Score = 37.1 bits (82), Expect = 0.86
Identities = 20/34 (58%), Positives = 25/34 (73%), Gaps = 2/34 (5%)
Query: 317 LAKEPWFHGPISRTTAE-KLV-VEDGEFLVREST 348
LAK+ W+ GPI+R AE KL V DG FLVR+S+
Sbjct: 379 LAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSS 412
>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Grb14 - Strongylocentrotus purpuratus
Length = 756
Score = 36.7 bits (81), Expect = 1.1
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 320 EPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKH 366
+PWFH ++R L + DG FL+RES G FVL+ + KH
Sbjct: 658 QPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKH 708
>UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2 domain containing 4B -
Strongylocentrotus purpuratus
Length = 470
Score = 36.7 bits (81), Expect = 1.1
Identities = 28/65 (43%), Positives = 35/65 (53%), Gaps = 7/65 (10%)
Query: 311 EAQAALL--AKE--PWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLH 364
E QA LL KE PWFHG I+R AE L+ +G FLVR S G + L+ +
Sbjct: 340 ERQAGLLKDTKEIAPWFHGIITRQQAEYLLFPKAEGHFLVRVSNRIWG-YALSFRDKERA 398
Query: 365 KHLLL 369
KH L+
Sbjct: 399 KHFLI 403
>UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 4 SCAF14752, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 810
Score = 36.7 bits (81), Expect = 1.1
Identities = 14/27 (51%), Positives = 21/27 (77%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFL 343
LA++ W+HG I RT A++L+ + GEFL
Sbjct: 474 LAEQEWYHGAIPRTEAQELLRQQGEFL 500
>UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 250
Score = 36.7 bits (81), Expect = 1.1
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 317 LAKEPWFHGPISR--TTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L K W+ G S+ A EDG F+VR+S G++ LT + G+ K + ++ G
Sbjct: 1 LKKAEWYWGEASKEAVNARMRDTEDGTFIVRDSKRFPGEYTLTLMKGGVIKLIRIMYKDG 60
Query: 375 VVR-TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
++ F SV L+ Y+ L + + L P+ R
Sbjct: 61 KYGFSEPLTFKSVIDLVSYYKDRSLAQYNPKLDVKLAHPLSR 102
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 36.7 bits (81), Expect = 1.1
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>UniRef50_UPI0000F21B0F Cluster: PREDICTED: similar to
Methylenetetrahydrofolate dehydrogenase (NADP+
dependent); n=2; Danio rerio|Rep: PREDICTED: similar to
Methylenetetrahydrofolate dehydrogenase (NADP+
dependent) - Danio rerio
Length = 255
Score = 36.3 bits (80), Expect = 1.5
Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 2 AESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTS-MKKLDFDTRSQVAKECIA 60
A G V KP+ GWLH ++ GVTY V+ + V + M L T + K+ +A
Sbjct: 150 AGCGGLVNKPSHGWLHSSEKISGPGVTYVVKAQFDITVASEIMAVLALTTSLEDMKQRLA 209
Query: 61 RVCAAAGLRSADKKRRVSQAAARALTARPR 90
++ A RS ALT R
Sbjct: 210 KMVVATS-RSGQPVTTEDLGVCGALTVLMR 238
>UniRef50_UPI0000D57403 Cluster: PREDICTED: similar to C-terminal
PDZ domain ligand of neuronal nitric oxide synthase;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
C-terminal PDZ domain ligand of neuronal nitric oxide
synthase - Tribolium castaneum
Length = 644
Score = 36.3 bits (80), Expect = 1.5
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 23/179 (12%)
Query: 16 LHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSADKKR 75
LHP+ G+T+ +YIG ++V +++ A I A G+ KK+
Sbjct: 21 LHPEEAF-HHGITFQAKYIGMLDVPRPTSRVEI----VAAMRRIRYEFKAKGI----KKK 71
Query: 76 RVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDAD 135
+V+ +S G V L K + +G + H + R+ + S D+
Sbjct: 72 KVTV----------EVSVDGVKVTLRKKKKRKHW-LDDGKPLLLSHPIYRIFYVSH-DSQ 119
Query: 136 SLDYVAYVAKSAPPTEWRACYVLECGGRL-AQDVIATIGQAFELRFKEFLTKPSTLNLN 193
L +Y+A+ ++ C V + + A V+ TIGQAFE+ K + P NL+
Sbjct: 120 DLKIFSYIARDGASNVFK-CAVFKSNKKSQAMRVVRTIGQAFEVCHKLSINAPENENLD 177
>UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Protein
SH(2)A); n=23; Euteleostomi|Rep: SH2 domain-containing
protein 4A (Protein SH(2)A) - Homo sapiens (Human)
Length = 454
Score = 36.3 bits (80), Expect = 1.5
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
E PL A Q PWFHG ++ A +L++ G FL+R S G + L+
Sbjct: 329 EQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLS 387
Query: 361 RGLHKHLLL---VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
KH L+ D + ++ L++YH E PI S LLL
Sbjct: 388 EDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYH--KEEPITSLGKELLL 437
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 35.9 bits (79), Expect = 2.0
Identities = 35/111 (31%), Positives = 51/111 (45%), Gaps = 19/111 (17%)
Query: 320 EPWFHGPIS-----RTTAEKLV-------VEDGEFLVRESTACAGQFVLTGARRGLHKHL 367
E WFHG + R AEKL+ +DG FLVRES G + L+ R G +H
Sbjct: 500 ERWFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHC 559
Query: 368 LL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G R T + VFDS+ L+ ++ + P+ + + L PV
Sbjct: 560 RIHSRQESGSTRFYLTDNLVFDSLYRLMCHY--RDTPLRCNEFEMRLGSPV 608
>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF8684, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 966
Score = 35.9 bits (79), Expect = 2.0
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
Query: 322 WFHGPISRTTAEKL---VVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
W+H +SR+ AE + V DG FLVR+ A F ++ G KH + V
Sbjct: 747 WYHANLSRSQAENMLMRVPRDGAFLVRK-RAEPNSFAISFRAEGKIKHCRVQQEGQTVVL 805
Query: 379 KDRVFDSVPHLIKYH 393
FDS+ LI Y+
Sbjct: 806 GTSEFDSLVDLISYY 820
>UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF10147, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 35.9 bits (79), Expect = 2.0
Identities = 18/36 (50%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 321 PWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQF 354
PWF G +SR AEK + + G FLVRES + G+F
Sbjct: 59 PWFVGRVSRLEAEKRLRWQDPGVFLVRESESAPGEF 94
>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
protein similar to vertebrate phospholipase C, gamma 2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 270
Score = 35.9 bits (79), Expect = 2.0
Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 10/57 (17%)
Query: 320 EPWFHGPIS--RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKH 366
EPWFHG ++ R TAEKL+ + D FLVRES G + ++ RG +H
Sbjct: 52 EPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQH 108
>UniRef50_Q0PNF0 Cluster: Gulp-2; n=14; Amniota|Rep: Gulp-2 - Mus
musculus (Mouse)
Length = 304
Score = 35.9 bits (79), Expect = 2.0
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 5/76 (6%)
Query: 111 VLEGGDTIARHD--MPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDV 168
+LE +H+ + R+SF + D + ++ K + + CYV + + A+++
Sbjct: 81 ILEPKSKEVQHNCQLHRISFCADDKTDKRIFT-FICKDSESNK-HLCYVFD-SEKCAEEI 137
Query: 169 IATIGQAFELRFKEFL 184
TIGQAF+L +++FL
Sbjct: 138 TLTIGQAFDLAYRKFL 153
>UniRef50_Q026T3 Cluster: AAA ATPase precursor; n=1; Solibacter
usitatus Ellin6076|Rep: AAA ATPase precursor -
Solibacter usitatus (strain Ellin6076)
Length = 252
Score = 35.9 bits (79), Expect = 2.0
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Query: 360 RRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNE--------LPIVSADSALLLRK 411
R L +LL+D +G R D V D+V ++ + C+N LP V A SA+L +
Sbjct: 148 RMALDSEVLLLDDLGAHRVTDWVQDTVTSIVTHRCNNRKPLIATTNLPDVDAGSAVLQKT 207
Query: 412 PV 413
PV
Sbjct: 208 PV 209
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 35.9 bits (79), Expect = 2.0
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPI 373
LA + W++G I+R+ + ++ DG+FL+R+S G + ++ G +KH +
Sbjct: 443 LAGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQ 502
Query: 374 GVVRTKDRVFDSVPHLIKYH 393
+ R F S+ L+ ++
Sbjct: 503 NMYCIGQRKFHSLDQLVDHY 522
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 35.9 bits (79), Expect = 2.0
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 13/100 (13%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVED----GEFLVRESTACAGQFVLT----- 357
P A+ + E W+ G I R AE+LV+ G FL+RE A +F LT
Sbjct: 123 PRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTD 182
Query: 358 GARRG---LHKHLLLVD-PIGVVRTKDRVFDSVPHLIKYH 393
R G H + +D G T R F S+ L++Y+
Sbjct: 183 DQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYY 222
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 35.9 bits (79), Expect = 2.0
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
Query: 308 LTAEAQAALLAKEP-WFHGPISRTTAEKLVVED---GEFLVRESTACAGQFVLTGARRGL 363
L E A + E W+HG + R +AE + G +LVRES G +VL+ R
Sbjct: 69 LNGERPAIIAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTG 128
Query: 364 HKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCS 395
H + G R F S+ L+ Y+ S
Sbjct: 129 INHFRITAVCGDFYIGGRQFISLSDLVGYYTS 160
>UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae
str. PEST
Length = 397
Score = 35.9 bits (79), Expect = 2.0
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR-T 378
W+ G ISR A++ +++ DG FLVR++ AG+F L + G + + + G T
Sbjct: 142 WYWGKISRDVAKEKMMDAPDGSFLVRDAINDAGEFTLVLKKDGTDRPIKIYHKNGKYGFT 201
Query: 379 KDRVFDSVPHLI 390
++ F+S+ +I
Sbjct: 202 QECTFESLVGMI 213
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 35.9 bits (79), Expect = 2.0
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 35.9 bits (79), Expect = 2.0
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHK 365
T + + A W++G ++R AE + E +G+FL+R+S + F ++ G +K
Sbjct: 272 TGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNK 331
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
H + V R F ++ L++++ + PI +++
Sbjct: 332 HFKVQLVDNVYCIGQRRFHTMDELVEHY--KKAPIFTSE 368
>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SH2 domain containing 4B - Tribolium
castaneum
Length = 412
Score = 35.5 bits (78), Expect = 2.6
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
Query: 320 EPWFHGPISRTTAEKLVVED--GEFLVRESTACAGQFVLTGARRGLHKHLLL 369
E WFHG I+R+ AEKL+++ G FLVR S G + A+ KH L+
Sbjct: 307 ESWFHGLITRSEAEKLLLDRPYGSFLVRLSERIWGYAISYRAKEKC-KHYLV 357
>UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3208-PA, isoform A - Tribolium castaneum
Length = 452
Score = 35.5 bits (78), Expect = 2.6
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Query: 323 FHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDPIGVVRT 378
+HG I+ A+ L+ E+G +LVR S + GQF + +H + L DP +
Sbjct: 47 YHGAITHIQAQNLLSPHENGAYLVRSSRSANGQFHTLSLKFNDKIHHYKLFYDPNSGLYV 106
Query: 379 KDRVFDSVPHLI 390
+++ +D V L+
Sbjct: 107 REKRYDCVRSLV 118
>UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 492
Score = 35.5 bits (78), Expect = 2.6
Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 26/118 (22%)
Query: 322 WFHGPISRTTAEKLVVE-------------DGEFLVRESTACAGQFVLTGARRGLHKHLL 368
WFHG + R AE+L+++ +G FLVR+S+ G FV++ R H L
Sbjct: 69 WFHGLMERKVAEELLLKSPFRGHTSHPSSREGLFLVRQSSNRGGHFVISVCTRNHCNHYL 128
Query: 369 L--VDPIGVV---RTKDRVFD----SVPHLIKYHCSNELPIVSADSALLLRKPVLRSS 417
+ ++ + V R++DR D + +LI+ C P+ +S L+L++P+LR++
Sbjct: 129 IETIESMFYVRRDRSEDRGRDIQACDLRNLIQ--CYRTTPL--DESGLVLKEPLLRTT 182
>UniRef50_O84156 Cluster: Phospholipase D Endonuclease Superfamily;
n=2; Chlamydia trachomatis|Rep: Phospholipase D
Endonuclease Superfamily - Chlamydia trachomatis
Length = 383
Score = 35.5 bits (78), Expect = 2.6
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 359 ARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
A+RG+ + + ++++ + VP +KYHC LP+ +S ++LR
Sbjct: 81 AQRGIFMRIYTISSDDIIQSLIQTSHHVPVEVKYHCGESLPVACQNSRVVLR 132
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 35.5 bits (78), Expect = 2.6
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 317 LAKEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVD 371
L E WF +SRT AE ++ +G F+VR S+ + L+ G H H+ L +
Sbjct: 313 LDSEEWFFPQLSRTRAENILKGEGREGGFVVRNSSR-ENMYTLSICHEGQVRHYHIKLDE 371
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSN 396
++ F S+ LI+YH N
Sbjct: 372 SNKYFISEKHRFPSIKELIEYHKLN 396
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 312 AQAALLAKEPWFHGPISRTTA-EKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
A+ + EPWF G ISR+ A +L E G FL+R S + +VL+ +H
Sbjct: 68 AERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHY 127
Query: 368 LLVDPI-GVVRTKDRV-FDSVPHLIKYHCSNEL 398
+ G + + V F S+P L+ YH + L
Sbjct: 128 KIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSL 160
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 35.5 bits (78), Expect = 2.6
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 13/88 (14%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRT 378
W++ ISR AEKL+++ +G F+VR+S V + + ++ + + T
Sbjct: 239 WYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKET 298
Query: 379 KDR----------VFDSVPHLIKYHCSN 396
D VFDS+P LI YH N
Sbjct: 299 NDNPKRYYVAEKYVFDSIPLLINYHQHN 326
>UniRef50_Q9UBP9 Cluster: PTB domain-containing engulfment adapter
protein 1; n=23; Euteleostomi|Rep: PTB domain-containing
engulfment adapter protein 1 - Homo sapiens (Human)
Length = 304
Score = 35.5 bits (78), Expect = 2.6
Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 125 RVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFL 184
R+SF + D + ++ K + + CYV + + A+++ TIGQAF+L +++FL
Sbjct: 97 RISFCADDKTDKRIFT-FICKDSESNK-HLCYVFD-SEKCAEEITLTIGQAFDLAYRKFL 153
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 35.5 bits (78), Expect = 2.6
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 321 PWFHGPISRTTAEKLVVED---GEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PW+ G ISR AE+++++ G FL+RES + G+F ++ +H +L + G
Sbjct: 59 PWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKY 118
Query: 377 RTKDRVFDSVPHLIKYH 393
+ F+S+ L+ ++
Sbjct: 119 FLWEEKFNSLNELVDFY 135
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 35.1 bits (77), Expect = 3.5
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 11/91 (12%)
Query: 317 LAKEPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLT------GARRG--LHK 365
L K W+ I+R+ AE L+ +DG FLVR+S G++ ++ G G H
Sbjct: 235 LEKYDWYCKNINRSQAENLLKTENKDGGFLVRDSGKFTGKYTVSVFTKAGGETSGSCRHY 294
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSN 396
++LL + F ++P LI YH N
Sbjct: 295 NILLTADGQFYLAEKHNFTNIPELINYHQHN 325
>UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell
linker; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to B-cell linker - Strongylocentrotus
purpuratus
Length = 591
Score = 35.1 bits (77), Expect = 3.5
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 11/115 (9%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTAC--AGQFVLTGARR 361
P Q L PW++G I R +EK + + DG F+VR ST A + L
Sbjct: 471 PPAQPQQVNELEGHPWYNGGIGRQESEKYLHQCRKDGAFIVRNSTRGDPANPYSLALWFN 530
Query: 362 GLHKHLLLVD------PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
G ++L + +G + + FD+ LI++H +N L + + +L+
Sbjct: 531 GRVRNLQIRKRKDQRYALGSRKDNELAFDTPVQLIEHHMTNSLILAQDEGKTILK 585
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 35.1 bits (77), Expect = 3.5
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter
protein E.; n=1; Xenopus tropicalis|Rep: SH2
domain-containing adapter protein E. - Xenopus
tropicalis
Length = 437
Score = 35.1 bits (77), Expect = 3.5
Identities = 22/98 (22%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L K+ W+HG ++R AE L+ + +L+R S + ++ + H+++
Sbjct: 332 LEKQSWYHGSVTRDQAESLLDSCPEASYLLRNSGSGNSKYSIALKTSQGCVHIIVAQTKN 391
Query: 375 VVRTKDRV---FDSVPHLIKYHCSNELPIVSADSALLL 409
T ++ F+S+P ++ ++ S +LP + LL
Sbjct: 392 NKFTLSQMCGAFNSIPEVVHHYSSQKLPFKGSKHISLL 429
>UniRef50_Q21429 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 272
Score = 35.1 bits (77), Expect = 3.5
Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 10/163 (6%)
Query: 11 PARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRS 70
P W + + G +AV+Y+G +L ++++ R + + CI V ++
Sbjct: 9 PTSSWGESAKHVNASGDRFAVKYMGYAPILQTIRERPIADRDALVRHCINTVVSS----R 64
Query: 71 ADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDT--IARHDMPRVSF 128
A + V Q P +S ++ L +SS IT ++ G T + R+ ++S
Sbjct: 65 ATHEYSVIQHEG---VVGPYVSVYQLDLFLNISSFTITCFHIQDGRTHLLGRYKNNQISH 121
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIAT 171
+ D Y+ V K TE R C V +A + + T
Sbjct: 122 YKYREIDGRHYLGIVMKIG-RTEKRECNVFMLDNDIALNDLTT 163
>UniRef50_A1CSQ5 Cluster: Acetyltransferase, CysE/LacA/LpxA/NodL
family; n=9; Pezizomycotina|Rep: Acetyltransferase,
CysE/LacA/LpxA/NodL family - Aspergillus clavatus
Length = 215
Score = 35.1 bits (77), Expect = 3.5
Identities = 20/50 (40%), Positives = 24/50 (48%)
Query: 311 EAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGAR 360
EA ALLA+EPW GPI + V +G F+ T V GAR
Sbjct: 74 EADEALLAREPWIEGPIRIDYGFNVRVGEGAFINSYCTIIDTCLVTIGAR 123
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 35.1 bits (77), Expect = 3.5
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLT------GARRGL--HKHLLLV 370
WF G ISR+ +E+L+ + +G F+VR S+ G + ++ ++G H H+
Sbjct: 296 WFAGNISRSQSEQLLRQKGKEGAFMVRNSSQ-VGMYTVSLFSKAVNDKKGTVKHYHVHTN 354
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVS 402
+ ++ FDS+P LI YH N +++
Sbjct: 355 AENKLYLAENYCFDSIPKLIHYHQHNSAGMIT 386
>UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 391
Score = 34.7 bits (76), Expect = 4.6
Identities = 17/34 (50%), Positives = 25/34 (73%), Gaps = 2/34 (5%)
Query: 317 LAKEPWFHGPISRTTAE-KL-VVEDGEFLVREST 348
L ++PW+ GP+S+ AE KL +DG FLVR+S+
Sbjct: 239 LPRQPWYWGPMSQDEAEGKLDDADDGSFLVRDSS 272
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 34.7 bits (76), Expect = 4.6
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 10/66 (15%)
Query: 311 EAQAALLAKEPWFHGPI--SRTTAEKLVVE--------DGEFLVRESTACAGQFVLTGAR 360
+ Q L EPWFHG + R AE+L+ E DG FLVR S + L+ R
Sbjct: 506 DTQKDLHCTEPWFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWR 565
Query: 361 RGLHKH 366
G +H
Sbjct: 566 NGRVQH 571
>UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whole
genome shotgun sequence; n=8; Euteleostomi|Rep:
Chromosome undetermined SCAF15024, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 511
Score = 34.7 bits (76), Expect = 4.6
Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 12/117 (10%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT----- 357
P QA + E WF ISR AE+ ++ G +L+RES G F L+
Sbjct: 67 PSNYVGQADTMETEDWFFKDISRKDAERQLLAPANRAGSYLIRESETAKGSFSLSVRDVD 126
Query: 358 --GARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK-YHCSNELPIVSADSALLLRK 411
G H + L+D G + F + +IK YH N P + L RK
Sbjct: 127 DGGTDLVKHYKIRLLDNGGYYISPKISFTDISSMIKHYHNRNPEPEPPGKADGLCRK 183
>UniRef50_Q3JWB4 Cluster: Putative uncharacterized protein; n=7;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 881
Score = 34.7 bits (76), Expect = 4.6
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 53 QVAKECIARVCAAAGLRSADKKRRVSQAAARALTARPRMSHSGANV 98
Q+A++C AR AA G A ++ ++AA RA +AR R +GA V
Sbjct: 252 QLARQCAARRRAAGGEPRAAEREAAARAARRARSARRRADAAGAAV 297
>UniRef50_Q9XXE5 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 245
Score = 34.7 bits (76), Expect = 4.6
Identities = 15/44 (34%), Positives = 26/44 (59%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAG 352
TA Q + KEP++HG + R + ++ +G+F++R S AG
Sbjct: 5 TASMQRPSIEKEPYYHGFLPREDVKTVLKNNGDFVIRISEPQAG 48
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 34.7 bits (76), Expect = 4.6
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVRT 378
WFHG IS + +E + + +G FLVR ST+ G + ++ ++ G H + P G +
Sbjct: 424 WFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQV 483
Query: 379 KDRVFDSVPHLI 390
+ + SV LI
Sbjct: 484 NNSKYLSVKELI 495
>UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;
Theria|Rep: SH2 domain-containing protein 2A - Homo
sapiens (Human)
Length = 389
Score = 34.7 bits (76), Expect = 4.6
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 318 AKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV---DP 372
A WFHG I+R AE+L+ G +LVR S + A FVLT R +H LL D
Sbjct: 91 AAPAWFHGFITRREAERLLEPKPQGCYLVRFSES-AVTFVLTYRSRTCCRHFLLAQLRDG 149
Query: 373 IGVVRTKDRVFDSVPHLIKYHCSNEL 398
VV +D + L+ ++ ++ L
Sbjct: 150 RHVVLGEDSAHARLQDLLLHYTAHPL 175
>UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Grb2 adaptor protein -
Strongylocentrotus purpuratus
Length = 532
Score = 34.3 bits (75), Expect = 6.0
Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 3/39 (7%)
Query: 322 WFHGPISRTTAEKLV---VEDGEFLVRESTACAGQFVLT 357
WF G ISR AE+++ G+ L+RES A GQ+ L+
Sbjct: 206 WFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLS 244
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 34.3 bits (75), Expect = 6.0
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
+C ++ KE W++G ++R AE + + +G+FL+R+S + F ++
Sbjct: 280 DCDYISPSGSGRFAGKE-WYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKA 338
Query: 361 RGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
+ +KH + + R F S+ L++++ + PI +++
Sbjct: 339 QSKNKHFKVQLKESLYCIGQRKFHSMEELVEHY--KKAPIFTSE 380
>UniRef50_Q4QCT8 Cluster: Putative uncharacterized protein; n=2;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 2440
Score = 34.3 bits (75), Expect = 6.0
Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 10/145 (6%)
Query: 13 RGWLHPDSVLASDGVTYAVRYI-GCMEVLTSMKKLDFDTRSQVAKECIARVCAAAGLRSA 71
RG P S+L + A+ + G ++ + + F + EC+ RVC+ G +
Sbjct: 1163 RGGPSPSSLLLTSSSLGALPSVPGDLDSVGGGSGVVFTQLFPLLNECV-RVCSGGGSGGS 1221
Query: 72 DKKRRVSQAAARALTAR--PRMSHSGANVALTVSSKAITLAVLEGGDTIA-----RHDMP 124
K R + +R P + + A VA +V+ ++ A L+ T+A RHD+P
Sbjct: 1222 CKARGKCNRSEEPRVSRFSPSAAKTSAPVA-SVAPLSVAPASLDNSLTLAAASAVRHDLP 1280
Query: 125 RVSFASGGDADSLDYVAYVAKSAPP 149
V F S S + A ++PP
Sbjct: 1281 TVLFFSASCPASAERKPETATTSPP 1305
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 34.3 bits (75), Expect = 6.0
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGE----FLVRESTACAGQFVLT----G 358
P A A + E W+ G + R AE+L++ G FLVRES G + L+
Sbjct: 143 PSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWD 202
Query: 359 ARRG---LHKHLLLVDPIGVVRTKDRVFDSVPHLIKYH 393
RG H + +D G T FD++ L+K++
Sbjct: 203 EIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHY 240
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 34.3 bits (75), Expect = 6.0
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVED----GEFLVRESTACAGQFVLT 357
P A+ L E WF G I R AEK++ + G FL+R+S G F L+
Sbjct: 107 PSNYVAEYKSLDAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLS 161
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.133 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 383,637,575
Number of Sequences: 1657284
Number of extensions: 13199331
Number of successful extensions: 30136
Number of sequences better than 10.0: 260
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 29827
Number of HSP's gapped (non-prelim): 334
length of query: 418
length of database: 575,637,011
effective HSP length: 103
effective length of query: 315
effective length of database: 404,936,759
effective search space: 127555079085
effective search space used: 127555079085
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 74 (33.9 bits)
- SilkBase 1999-2023 -