Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002678-TA|BGIBMGA002678-PA|IPR006020|Phosphotyrosine
interaction region, IPR000980|SH2 motif
(418 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y09847-1|CAA70977.1| 583|Homo sapiens shc p66 protein. 200 7e-51
X68148-1|CAA48251.1| 473|Homo sapiens SHC transforming protein ... 200 7e-51
U73377-1|AAB49972.1| 583|Homo sapiens p66shc protein. 200 7e-51
BC014158-1|AAH14158.1| 474|Homo sapiens SHC (Src homology 2 dom... 200 7e-51
AL451085-14|CAI13250.1| 583|Homo sapiens SHC (Src homology 2 do... 200 7e-51
AL451085-13|CAI13249.1| 473|Homo sapiens SHC (Src homology 2 do... 200 7e-51
AL451085-12|CAI13251.1| 584|Homo sapiens SHC (Src homology 2 do... 200 7e-51
AL451085-11|CAI13248.1| 474|Homo sapiens SHC (Src homology 2 do... 200 7e-51
AB001451-1|BAA25798.1| 540|Homo sapiens Sck protein. 197 5e-50
D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc prot... 184 4e-46
D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc prot... 184 4e-46
AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 dom... 184 4e-46
AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 dom... 184 4e-46
BC033907-1|AAH33907.1| 630|Homo sapiens SHC (Src homology 2 dom... 183 9e-46
AY464565-1|AAR19363.1| 630|Homo sapiens rai-like protein RaLP p... 183 9e-46
BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 dom... 183 1e-45
AL451085-15|CAI13252.1| 200|Homo sapiens SHC (Src homology 2 do... 153 1e-36
BC033925-1|AAH33925.1| 369|Homo sapiens SHC1 protein protein. 128 3e-29
AL451085-17|CAI13254.1| 384|Homo sapiens SHC (Src homology 2 do... 128 3e-29
AL360254-1|CAB96175.1| 392|Homo sapiens SCK protein. 122 2e-27
AY358250-1|AAQ88617.1| 387|Homo sapiens LPAL6438 protein. 119 2e-26
AB208849-1|BAD92086.1| 377|Homo sapiens SHC (Src homology 2 dom... 116 2e-25
AL451085-10|CAI13247.1| 130|Homo sapiens SHC (Src homology 2 do... 112 2e-24
AL451085-16|CAI13253.1| 137|Homo sapiens SHC (Src homology 2 do... 103 2e-21
AL451085-9|CAI13246.1| 200|Homo sapiens SHC (Src homology 2 dom... 81 5e-15
AL451085-8|CAI13245.1| 296|Homo sapiens SHC (Src homology 2 dom... 79 2e-14
AL353150-1|CAI16864.1| 105|Homo sapiens SHC (Src homology 2 dom... 69 4e-11
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 64 1e-09
U92715-1|AAC39777.1| 825|Homo sapiens breast cancer antiestroge... 60 1e-08
BC039895-1|AAH39895.1| 825|Homo sapiens breast cancer anti-estr... 60 1e-08
AL359820-1|CAH73975.1| 825|Homo sapiens breast cancer anti-estr... 60 1e-08
AL109613-2|CAI18951.1| 734|Homo sapiens breast cancer anti-estr... 60 1e-08
AL109613-1|CAI18950.1| 825|Homo sapiens breast cancer anti-estr... 60 1e-08
AF124250-1|AAD28245.1| 825|Homo sapiens SH2-containing protein ... 60 1e-08
AY358406-1|AAQ88772.1| 576|Homo sapiens NSP1 protein. 57 1e-07
AF124249-1|AAD28244.1| 576|Homo sapiens SH2-containing protein ... 57 1e-07
BC006281-1|AAH06281.1| 576|Homo sapiens SH2 domain containing 3... 55 4e-07
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 55 5e-07
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 55 5e-07
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 55 5e-07
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 55 5e-07
AB000520-1|BAA22514.1| 632|Homo sapiens APS protein. 54 1e-06
AJ012793-1|CAB42642.1| 576|Homo sapiens lymphocyte adaptor prot... 53 2e-06
AF055581-1|AAC71695.1| 575|Homo sapiens adaptor protein Lnk pro... 53 2e-06
AB208911-1|BAD92148.1| 439|Homo sapiens lymphocyte adaptor prot... 53 2e-06
BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3... 52 4e-06
BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein. 52 4e-06
AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein. 52 4e-06
AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein. 52 4e-06
AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162586-3|CAI39762.1| 324|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162586-1|CAI39760.1| 196|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162426-3|CAI41178.1| 324|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3... 52 4e-06
AL162426-1|CAI41176.1| 196|Homo sapiens SH2 domain containing 3... 52 4e-06
AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein ... 52 4e-06
AL049924-1|CAB43208.1| 540|Homo sapiens hypothetical protein pr... 51 7e-06
AK027488-1|BAB55148.1| 426|Homo sapiens protein ( Homo sapiens ... 51 7e-06
AF227969-1|AAF73914.1| 683|Homo sapiens SH2-B gamma signaling p... 51 7e-06
AF227968-1|AAF73913.1| 671|Homo sapiens SH2-B beta signaling pr... 51 7e-06
AF227967-1|AAF73912.1| 756|Homo sapiens SH2-B alpha signaling p... 51 7e-06
AB037720-1|BAA92537.1| 730|Homo sapiens KIAA1299 protein protein. 51 7e-06
X75342-1|CAA53091.1| 596|Homo sapiens Shb protein. 50 1e-05
AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain c... 50 1e-05
AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain c... 50 1e-05
AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain c... 50 1e-05
BC010704-1|AAH10704.1| 426|Homo sapiens SH2B1 protein protein. 50 2e-05
AL390078-1|CAB98202.1| 247|Homo sapiens similar to (NP_033194.1... 50 2e-05
AK055673-1|BAB70981.1| 340|Homo sapiens protein ( Homo sapiens ... 50 2e-05
BC007206-1|AAH07206.1| 340|Homo sapiens Src homology 2 domain c... 49 3e-05
BC007586-1|AAH07586.1| 233|Homo sapiens SHF protein protein. 49 4e-05
BC117210-1|AAI17211.1| 495|Homo sapiens Src homology 2 domain c... 48 6e-05
AL162591-2|CAH72851.1| 495|Homo sapiens Src homology 2 domain c... 48 6e-05
AK074067-1|BAB84893.1| 309|Homo sapiens FLJ00138 protein protein. 48 6e-05
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 48 8e-05
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 48 8e-05
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 48 8e-05
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 48 8e-05
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 47 1e-04
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 47 1e-04
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 47 1e-04
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 47 1e-04
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 47 1e-04
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 47 1e-04
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 47 1e-04
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 47 1e-04
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 47 1e-04
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 45 4e-04
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 45 4e-04
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 45 4e-04
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 45 4e-04
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 45 4e-04
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 45 4e-04
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 45 4e-04
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 45 4e-04
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 45 4e-04
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 45 4e-04
X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein. 45 6e-04
CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein. 45 6e-04
BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT1... 45 6e-04
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 44 0.001
X83931-1|CAA58783.1| 539|Homo sapiens VAV protein. 43 0.002
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 43 0.002
AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric... 43 0.002
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 43 0.002
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 42 0.003
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 42 0.003
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 42 0.003
L76687-1|AAC15861.1| 540|Homo sapiens Grb14 protein. 42 0.003
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 42 0.003
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 42 0.003
BC053559-1|AAH53559.1| 540|Homo sapiens growth factor receptor-... 42 0.003
AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric ... 42 0.003
AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric ... 42 0.003
AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric... 42 0.003
AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric... 42 0.003
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 42 0.003
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 42 0.003
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 42 0.003
AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion... 42 0.003
AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoi... 42 0.003
AF455141-2|AAM61860.1| 55|Homo sapiens Src homology 2 domain-c... 42 0.003
AF455141-1|AAM61859.1| 165|Homo sapiens Src homology 2 domain-c... 42 0.003
AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoin... 42 0.003
AC110086-1|AAY24176.1| 172|Homo sapiens unknown protein. 42 0.003
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 42 0.003
X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphat... 42 0.004
X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein. 42 0.004
M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor r... 42 0.004
L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphat... 42 0.004
L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein ph... 42 0.004
D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphat... 42 0.004
CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein. 42 0.004
CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein. 42 0.004
BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine phosph... 42 0.004
BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein. 42 0.004
BC000631-1|AAH00631.1| 217|Homo sapiens growth factor receptor-... 42 0.004
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 42 0.004
AF498925-1|AAM21073.1| 217|Homo sapiens growth factor receptor-... 42 0.004
AF063618-1|AAC72075.1| 217|Homo sapiens growth factor receptor-... 42 0.004
M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholi... 41 0.007
DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma ... 41 0.007
AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma ... 41 0.007
AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma ... 41 0.007
AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein p... 41 0.007
Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate 5-... 40 0.016
X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma ... 40 0.016
M23612-1|AAA35865.1| 870|Homo sapiens GTPase-activating protein... 40 0.016
M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein... 40 0.016
BC054891-1|AAH54891.1| 313|Homo sapiens RASA1 protein protein. 40 0.016
BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activat... 40 0.016
BC020761-1|AAH20761.1| 317|Homo sapiens Unknown (protein for IM... 40 0.016
BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein. 40 0.016
BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1 p... 40 0.016
AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter pr... 40 0.016
AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine phosph... 40 0.016
AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1 p... 40 0.016
AF047348-1|AAC39767.1| 748|Homo sapiens adaptor protein X11beta... 40 0.016
AB209281-1|BAD92518.1| 752|Homo sapiens amyloid beta A4 precurs... 40 0.016
AB209106-1|BAD92343.1| 871|Homo sapiens RAS p21 protein activat... 40 0.016
BC068451-1|AAH68451.1| 357|Homo sapiens ANKS1B protein protein. 40 0.022
BC026313-1|AAH26313.2| 510|Homo sapiens ankyrin repeat and ster... 40 0.022
AY753193-1|AAV28691.1| 426|Homo sapiens AIDA1C transcript varia... 40 0.022
AY620824-1|AAT39519.1| 768|Homo sapiens AIDA-1bDelta Ank-2 prot... 40 0.022
AY356353-1|AAQ56189.1| 366|Homo sapiens cajalin 2 protein. 40 0.022
AY283057-1|AAP38184.2| 750|Homo sapiens AIDA-1bDAnk protein. 40 0.022
AY281132-1|AAP37613.1| 460|Homo sapiens AIDA-1a protein. 40 0.022
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 40 0.022
AF164792-1|AAF80756.1| 414|Homo sapiens putative 47 kDa protein... 40 0.022
AF145204-1|AAD33951.1| 955|Homo sapiens E2a-Pbx1-associated pro... 40 0.022
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 39 0.038
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 39 0.038
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 39 0.038
U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein. 39 0.038
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 39 0.038
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 39 0.038
D43772-1|BAA07827.1| 532|Homo sapiens GRB-7 SH2 domain protein ... 39 0.038
BT006686-1|AAP35332.1| 532|Homo sapiens growth factor receptor-... 39 0.038
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 39 0.038
BC006535-1|AAH06535.1| 532|Homo sapiens growth factor receptor-... 39 0.038
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 39 0.038
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 39 0.038
AK222870-1|BAD96590.1| 532|Homo sapiens growth factor receptor-... 39 0.038
AK222849-1|BAD96569.1| 532|Homo sapiens growth factor receptor-... 39 0.038
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 39 0.038
AF274875-1|AAG25938.1| 532|Homo sapiens growth factor receptor-... 39 0.038
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 39 0.038
AB008789-1|BAA29059.1| 532|Homo sapiens grb7 protein protein. 39 0.038
X16316-1|CAA34383.1| 797|Homo sapiens VAV protein. 38 0.050
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 38 0.050
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 38 0.066
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 38 0.066
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 38 0.066
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 38 0.066
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 38 0.066
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 38 0.066
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 38 0.066
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 38 0.087
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 38 0.087
BC049213-1|AAH49213.1| 460|Homo sapiens ANKS1A protein protein. 38 0.087
BC031934-1|AAH31934.1| 570|Homo sapiens ANKS1A protein protein. 38 0.087
BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein. 38 0.087
BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein. 38 0.087
BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein. 38 0.087
BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein. 38 0.087
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 38 0.087
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 38 0.087
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 38 0.087
AB208914-1|BAD92151.1| 1278|Homo sapiens 1-phosphatidylinositol-... 38 0.087
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 37 0.12
BC026233-1|AAH26233.1| 64|Homo sapiens LOC400581 protein protein. 37 0.12
BC020082-1|AAH20082.1| 535|Homo sapiens suppressor of cytokine ... 37 0.12
AL731544-3|CAI14998.1| 431|Homo sapiens novel SH2 domain-contai... 37 0.12
AB006968-1|BAA22538.1| 535|Homo sapiens CIS4 protein. 37 0.12
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 37 0.15
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 37 0.15
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 37 0.15
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 37 0.15
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 37 0.15
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 37 0.15
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 37 0.15
AB014719-1|BAA34734.1| 749|Homo sapiens XllL protein. 37 0.15
BC082982-1|AAH82982.1| 454|Homo sapiens SH2D4A protein protein. 36 0.20
BC014525-1|AAH14525.2| 338|Homo sapiens SH2D4A protein protein. 36 0.20
AK024799-1|BAB15010.1| 454|Homo sapiens protein ( Homo sapiens ... 36 0.20
AK024620-1|BAB14935.1| 272|Homo sapiens protein ( Homo sapiens ... 36 0.20
X62055-1|CAA43982.1| 597|Homo sapiens protein-tyrosine phospha... 36 0.27
U47924-18|AAB51323.1| 595|Homo sapiens protein tyrosine phospha... 36 0.27
U47924-17|AAB51322.1| 556|Homo sapiens protein tyrosine phospha... 36 0.27
M77273-1|AAA36610.1| 595|Homo sapiens tyrosine phosphatase prot... 36 0.27
M74903-1|AAA35963.1| 595|Homo sapiens hematopoietic cell phopha... 36 0.27
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 36 0.27
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 36 0.27
BT007390-1|AAP36054.1| 597|Homo sapiens protein tyrosine phosph... 36 0.27
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 36 0.27
BC007667-1|AAH07667.1| 597|Homo sapiens protein tyrosine phosph... 36 0.27
BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2 p... 36 0.27
BC002523-1|AAH02523.1| 597|Homo sapiens protein tyrosine phosph... 36 0.27
BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2 p... 36 0.27
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 36 0.27
AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline ... 36 0.27
AK223629-1|BAD97349.1| 595|Homo sapiens protein tyrosine phosph... 36 0.27
AF178946-1|AAD53317.1| 624|Homo sapiens 70 kDa SHP-1L protein p... 36 0.27
AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein. 36 0.27
AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein. 36 0.27
AB079851-2|BAC81775.1| 595|Homo sapiens protein tyrosine phosph... 36 0.27
AB079851-1|BAC81774.1| 597|Homo sapiens protein tyrosine phosph... 36 0.27
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 36 0.35
X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for ... 36 0.35
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 36 0.35
U52518-1|AAC50541.1| 217|Homo sapiens Grb2-related adaptor prot... 36 0.35
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 36 0.35
M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein. 36 0.35
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 36 0.35
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 36 0.35
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 36 0.35
CR541966-1|CAG46764.1| 217|Homo sapiens GRAP protein. 36 0.35
CR541941-1|CAG46739.1| 217|Homo sapiens GRAP protein. 36 0.35
BT019981-1|AAV38784.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.35
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 36 0.35
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 36 0.35
BC063035-1|AAH63035.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.35
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 36 0.35
BC035856-1|AAH35856.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.35
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 36 0.35
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 36 0.35
AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2... 36 0.35
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 36 0.35
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 36 0.35
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 36 0.35
AF200715-1|AAF08006.1| 304|Homo sapiens PTB domain adaptor prot... 36 0.35
AF191771-1|AAF18975.1| 304|Homo sapiens CED-6 protein protein. 36 0.35
AB209622-1|BAD92859.1| 376|Homo sapiens IL2-inducible T-cell ki... 36 0.35
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 35 0.46
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 35 0.46
AY763100-1|AAV34675.1| 371|Homo sapiens SH2 domain containing a... 35 0.46
AY763098-1|AAV34673.1| 361|Homo sapiens SH2 domain containing a... 35 0.46
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 35 0.46
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 35 0.61
BC012107-1|AAH12107.1| 389|Homo sapiens SH2 domain protein 2A p... 35 0.61
AL590666-2|CAI16337.1| 389|Homo sapiens SH2 domain protein 2A p... 35 0.61
AL590666-1|CAI16336.1| 371|Homo sapiens SH2 domain protein 2A p... 35 0.61
AL158169-2|CAH70008.1| 371|Homo sapiens SH2 domain protein 2A p... 35 0.61
AL158169-1|CAH70007.1| 389|Homo sapiens SH2 domain protein 2A p... 35 0.61
AK222737-1|BAD96457.1| 389|Homo sapiens SH2 domain protein 2A v... 35 0.61
AJ000553-1|CAA04185.1| 389|Homo sapiens T lymphocyte specific a... 35 0.61
AF106072-1|AAF69027.1| 389|Homo sapiens T cell-specific adapter... 35 0.61
AF097744-1|AAF43260.1| 389|Homo sapiens VEGF receptor-associate... 35 0.61
AF051325-1|AAC99298.1| 371|Homo sapiens SH3 domain containing a... 35 0.61
AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein... 35 0.61
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 34 0.81
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 34 0.81
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 34 1.1
Z22641-1|CAA80354.1| 459|Homo sapiens a2-chimaerin protein. 34 1.1
U66065-1|AAC50671.1| 536|Homo sapiens Grb10- and Grb-IR-related... 34 1.1
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 34 1.1
U34355-1|AAA88819.1| 548|Homo sapiens Grb-IR protein. 34 1.1
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 34 1.1
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 34 1.1
D86962-1|BAA13198.2| 605|Homo sapiens KIAA0207 protein. 34 1.1
BC024285-1|AAH24285.1| 536|Homo sapiens growth factor receptor-... 34 1.1
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 34 1.1
BC011393-1|AAH11393.1| 459|Homo sapiens chimerin (chimaerin) 1 ... 34 1.1
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 34 1.1
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 34 1.1
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 34 1.1
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 34 1.1
AJ271366-1|CAB96542.1| 594|Homo sapiens putative adaptor protei... 34 1.1
AF073378-2|AAC83654.1| 548|Homo sapiens growth factor receptor-... 34 1.1
AF073378-1|AAC83655.1| 594|Homo sapiens growth factor receptor-... 34 1.1
AF001534-1|AAB81134.1| 594|Homo sapiens insulin receptor bindin... 34 1.1
AF000017-1|AAC19748.1| 594|Homo sapiens adapter protein protein. 34 1.1
AC080092-1|AAS07426.1| 196|Homo sapiens unknown protein. 34 1.1
AC020596-1|AAY14940.1| 176|Homo sapiens unknown protein. 34 1.1
Z82206-3|CAI42713.1| 330|Homo sapiens GRB2-related adaptor prot... 33 1.4
Y18051-1|CAA77021.1| 330|Homo sapiens GADS protein protein. 33 1.4
U15528-2|AAA82880.1| 595|Homo sapiens protein tyrosine phosphat... 33 1.4
U15528-1|AAA82879.1| 556|Homo sapiens protein tyrosine phosphat... 33 1.4
CR541849-1|CAG46647.1| 330|Homo sapiens GRAP2 protein. 33 1.4
CR536524-1|CAG38761.1| 330|Homo sapiens GRAP2 protein. 33 1.4
CR456498-1|CAG30384.1| 330|Homo sapiens GRAP2 protein. 33 1.4
BC026002-1|AAH26002.1| 330|Homo sapiens GRAP2 protein protein. 33 1.4
BC025692-1|AAH25692.1| 330|Homo sapiens GRB2-related adaptor pr... 33 1.4
AY069959-1|AAL58573.1| 330|Homo sapiens Mona protein. 33 1.4
AJ011736-1|CAA09757.1| 330|Homo sapiens growth factor receptor ... 33 1.4
AF236120-1|AAF60320.1| 330|Homo sapiens adapter protein GRID pr... 33 1.4
AF236119-1|AAF60319.1| 330|Homo sapiens adapter protein GRID pr... 33 1.4
AF129476-1|AAD41782.1| 330|Homo sapiens hematopoietic cell-asso... 33 1.4
AF121002-1|AAF31758.1| 330|Homo sapiens SH3-SH2-SH3 adaptor pro... 33 1.4
AF102694-1|AAD04926.1| 330|Homo sapiens Grb2-related adaptor pr... 33 1.4
AF090456-1|AAD13027.1| 330|Homo sapiens Grb-2-like protein prot... 33 1.4
AF042380-1|AAC69273.1| 330|Homo sapiens Grf40 adaptor protein p... 33 1.4
CR542043-1|CAG46840.1| 128|Homo sapiens yndrome); complete cds,... 33 1.9
CR542031-1|CAG46828.1| 128|Homo sapiens yndrome); complete cds,... 33 1.9
BC020732-1|AAH20732.1| 128|Homo sapiens SH2 domain protein 1A, ... 33 1.9
AY190323-1|AAO41715.1| 298|Homo sapiens SH2A protein. 33 1.9
AL023657-1|CAA19222.1| 128|Homo sapiens SH2D1A protein. 33 1.9
AL022718-4|CAA18777.1| 128|Homo sapiens SH2 domain protein 1A, ... 33 1.9
AF100543-1|AAC79716.1| 62|Homo sapiens SH2 domain protein 1A i... 33 1.9
AF100541-1|AAC79714.1| 125|Homo sapiens SH2 domain protein 1A i... 33 1.9
AF100540-1|AAC79713.1| 58|Homo sapiens SH2 domain protein 1A i... 33 1.9
AF100539-1|AAC79712.1| 76|Homo sapiens SH2 domain protein 1A i... 33 1.9
AF073019-1|AAC62631.1| 128|Homo sapiens T cell signal transduct... 33 1.9
AF072930-1|AAC62630.1| 128|Homo sapiens T cell signal transduct... 33 1.9
U69276-1|AAB08431.1| 536|Homo sapiens hGrbIRbeta/hGrb10 protein. 32 3.3
BX572623-2|CAM12863.1| 308|Homo sapiens low density lipoprotein... 32 3.3
BC029770-1|AAH29770.2| 308|Homo sapiens low density lipoprotein... 32 3.3
AY389348-1|AAQ90407.1| 308|Homo sapiens LDL receptor adaptor pr... 32 3.3
AL606491-1|CAI16483.1| 308|Homo sapiens low density lipoprotein... 32 3.3
AK024397-1|BAB14908.1| 221|Homo sapiens protein ( Homo sapiens ... 32 3.3
BC025237-1|AAH25237.1| 352|Homo sapiens hematopoietic SH2 domai... 31 5.7
AY319652-1|AAQ81285.1| 352|Homo sapiens ALX protein. 31 5.7
AK027792-1|BAB55372.1| 352|Homo sapiens protein ( Homo sapiens ... 31 5.7
AF100542-1|AAC79715.1| 76|Homo sapiens SH2 domain protein 1A i... 31 5.7
X80907-1|CAA56868.1| 728|Homo sapiens p85 beta subunit of phosp... 31 7.6
BC090249-1|AAH90249.1| 728|Homo sapiens phosphoinositide-3-kina... 31 7.6
BC070082-1|AAH70082.1| 728|Homo sapiens phosphoinositide-3-kina... 31 7.6
BC014170-1|AAH14170.2| 324|Homo sapiens PIK3R2 protein protein. 31 7.6
BC011917-1|AAH11917.2| 388|Homo sapiens PIK3R2 protein protein. 31 7.6
AC007192-2|AAD22671.1| 728|Homo sapiens P85B_HUMAN protein. 31 7.6
>Y09847-1|CAA70977.1| 583|Homo sapiens shc p66 protein.
Length = 583
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 197
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 198 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 257
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 258 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 315
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 316 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 359
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 473 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 532
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 533 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 581
>X68148-1|CAA48251.1| 473|Homo sapiens SHC transforming protein
protein.
Length = 473
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 147
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 148 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 205
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 206 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 249
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 363 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 422
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 423 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 471
>U73377-1|AAB49972.1| 583|Homo sapiens p66shc protein.
Length = 583
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 197
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 198 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 257
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 258 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 315
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 316 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 359
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 473 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 532
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 533 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 581
>BC014158-1|AAH14158.1| 474|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 1 protein.
Length = 474
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 147
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 148 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 205
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 206 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 249
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 364 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 423
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 424 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 472
>AL451085-14|CAI13250.1| 583|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 583
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 197
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 198 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 257
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 258 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 315
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 316 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 359
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 473 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 532
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 533 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 581
>AL451085-13|CAI13249.1| 473|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 473
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 147
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 148 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 205
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 206 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 249
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 363 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 422
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 423 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 471
>AL451085-12|CAI13251.1| 584|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 584
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 197
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 198 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 257
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 258 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 315
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 316 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 359
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 474 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 533
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 534 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 582
>AL451085-11|CAI13248.1| 474|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 474
Score = 200 bits (488), Expect = 7e-51
Identities = 103/224 (45%), Positives = 139/224 (62%), Gaps = 9/224 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L + IA H M
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHM 147
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
+SFASGGD D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 148 QSISFASGGDPDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 205
Query: 184 LTKPSTL-NLNGSLPSCESACGLVE-----DREYYNDMPDKVPP 221
L P L + + + + E D +YYND P K PP
Sbjct: 206 LRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 249
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 364 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 423
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 424 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 472
>AB001451-1|BAA25798.1| 540|Homo sapiens Sck protein.
Length = 540
Score = 197 bits (481), Expect = 5e-50
Identities = 105/223 (47%), Positives = 144/223 (64%), Gaps = 9/223 (4%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSF+ KPA GWLHPD+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I R+
Sbjct: 87 GSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHE 146
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G+R + KK+ ++A A L + + +G ++++ +S+ ++L+V IA H M
Sbjct: 147 AVPGVRGSWKKKAPNKALASVL-GKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHM 205
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
P +SFASGGD D DYVAYVAK P RAC++LEC LAQ +I+T+GQAFELRFK++
Sbjct: 206 PSISFASGGDTDMTDYVAYVAKD--PINQRACHILECCEGLAQSIISTVGQAFELRFKQY 263
Query: 184 LTKPSTLNLNGSLPSC--ESACGLVED---REYYNDMPDKVPP 221
L P + L + ESA G ED YYN +P K PP
Sbjct: 264 LHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPP 306
Score = 116 bits (279), Expect = 2e-25
Identities = 56/99 (56%), Positives = 71/99 (71%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L +EPW+HG +SR AE+++ DG+FLVR+S GQ+VLTG G KHLLLVDP GVV
Sbjct: 440 LRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV 499
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD +F+S+ HLI +H N PIV+A+S L LR V R
Sbjct: 500 RTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSR 538
>D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc
protein.
Length = 474
Score = 184 bits (449), Expect = 4e-46
Identities = 95/218 (43%), Positives = 134/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 16 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 75
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 76 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 135
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 136 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 193
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 194 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 231
Score = 124 bits (300), Expect = 4e-28
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 329 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 388
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G +RTKDRVFDS+ HLI
Sbjct: 389 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLIN 448
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 449 HHLESSLPIVSAGSELCLQQPVER 472
>D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc
protein.
Length = 594
Score = 184 bits (449), Expect = 4e-46
Identities = 95/218 (43%), Positives = 134/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 136 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 195
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 196 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 255
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 256 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 313
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 314 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 351
Score = 124 bits (300), Expect = 4e-28
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 449 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 508
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G +RTKDRVFDS+ HLI
Sbjct: 509 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLIN 568
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 569 HHLESSLPIVSAGSELCLQQPVER 592
>AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 184 bits (449), Expect = 4e-46
Identities = 95/218 (43%), Positives = 134/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 136 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 195
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 196 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 255
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 256 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 313
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 314 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 351
Score = 124 bits (300), Expect = 4e-28
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 449 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 508
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G +RTKDRVFDS+ HLI
Sbjct: 509 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLIN 568
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 569 HHLESSLPIVSAGSELCLQQPVER 592
>AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 184 bits (449), Expect = 4e-46
Identities = 95/218 (43%), Positives = 134/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 136 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 195
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 196 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 255
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYVAK P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 256 ASGGDPDTTDYVAYVAKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 313
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 314 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 351
Score = 124 bits (300), Expect = 4e-28
Identities = 66/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 449 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 508
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G +RTKDRVFDS+ HLI
Sbjct: 509 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLIN 568
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 569 HHLESSLPIVSAGSELCLQQPVER 592
>BC033907-1|AAH33907.1| 630|Homo sapiens SHC (Src homology 2 domain
containing) family, member 4 protein.
Length = 630
Score = 183 bits (446), Expect = 9e-46
Identities = 94/198 (47%), Positives = 124/198 (62%), Gaps = 4/198 (2%)
Query: 26 GVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAA-GLRSADKKRRVSQAAARA 84
G+ Y VRY+GC+EVL SM+ LDF R+QV +E I+R+C A G A KKR+
Sbjct: 189 GMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPVEFLST 248
Query: 85 LTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVA 144
+ + + SG N+ LT+S+ ++TL L+ IA H M +SFASGGD D+ DYVAYVA
Sbjct: 249 VLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVA 308
Query: 145 KSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS-TLNLNGSLPSCESAC 203
K P RAC++LEC +AQDVI+TIGQAFELRFK++L PS + +S
Sbjct: 309 KD--PVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVHIDSHA 366
Query: 204 GLVEDREYYNDMPDKVPP 221
ED EYYN++P K PP
Sbjct: 367 EEREDHEYYNEIPGKQPP 384
Score = 119 bits (286), Expect = 2e-26
Identities = 56/102 (54%), Positives = 74/102 (72%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L E +HG +SR AE L+V+DG+FLVRES GQ+VL+G + G KHLLLVDP G V
Sbjct: 521 LWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKV 580
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSSS 418
RTKD VFD+V HLI+YH N LPI+S+ S + L++PV + ++
Sbjct: 581 RTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNN 622
>AY464565-1|AAR19363.1| 630|Homo sapiens rai-like protein RaLP
protein.
Length = 630
Score = 183 bits (446), Expect = 9e-46
Identities = 94/198 (47%), Positives = 124/198 (62%), Gaps = 4/198 (2%)
Query: 26 GVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCAAA-GLRSADKKRRVSQAAARA 84
G+ Y VRY+GC+EVL SM+ LDF R+QV +E I+R+C A G A KKR+
Sbjct: 189 GMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPVKFLST 248
Query: 85 LTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVA 144
+ + + SG N+ LT+S+ ++TL L+ IA H M +SFASGGD D+ DYVAYVA
Sbjct: 249 VLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVA 308
Query: 145 KSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS-TLNLNGSLPSCESAC 203
K P RAC++LEC +AQDVI+TIGQAFELRFK++L PS + +S
Sbjct: 309 KD--PVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVHIDSHA 366
Query: 204 GLVEDREYYNDMPDKVPP 221
ED EYYN++P K PP
Sbjct: 367 EEREDHEYYNEIPGKQPP 384
Score = 119 bits (286), Expect = 2e-26
Identities = 56/102 (54%), Positives = 74/102 (72%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L E +HG +SR AE L+V+DG+FLVRES GQ+VL+G + G KHLLLVDP G V
Sbjct: 521 LWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKV 580
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSSS 418
RTKD VFD+V HLI+YH N LPI+S+ S + L++PV + ++
Sbjct: 581 RTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNN 622
>BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 183 bits (445), Expect = 1e-45
Identities = 94/218 (43%), Positives = 133/218 (61%), Gaps = 8/218 (3%)
Query: 10 KPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC-AAAGL 68
+P RG H + GVTY V+Y+GC+EVL SM+ LDF TR+Q+ +E I+RVC A G
Sbjct: 136 RPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGA 195
Query: 69 RSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSF 128
+ A KKR+ ++ + + +G +++LT+S+ ++ L + IA H M +SF
Sbjct: 196 KGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISF 255
Query: 129 ASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPS 188
ASGGD D+ DYVAYV K P RAC++LEC LAQDVI +IGQAFELRFK++L P+
Sbjct: 256 ASGGDPDTTDYVAYVTKD--PVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPT 313
Query: 189 TL-NLNGSLPSCESAC----GLVEDREYYNDMPDKVPP 221
+ L+ + S + G D YYN +P K+PP
Sbjct: 314 KIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPP 351
Score = 123 bits (296), Expect = 1e-27
Identities = 65/144 (45%), Positives = 85/144 (59%), Gaps = 4/144 (2%)
Query: 276 DIFDMQPFXXXXXXXXXXXXXXXXXXXXECAPLTAEAQAALLAKE----PWFHGPISRTT 331
D+FDM+PF +P++ A A + +E W+ G +SR
Sbjct: 449 DLFDMKPFEDALKNQPLGPVLSKAASVECISPVSPRAPDAKMLEELQAETWYQGEMSRKE 508
Query: 332 AEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIK 391
AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G ++TKDRVFDS+ HLI
Sbjct: 509 AEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIQTKDRVFDSISHLIN 568
Query: 392 YHCSNELPIVSADSALLLRKPVLR 415
+H + LPIVSA S L L++PV R
Sbjct: 569 HHLESSLPIVSAGSELCLQQPVER 592
>AL451085-15|CAI13252.1| 200|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 200
Score = 153 bits (370), Expect = 1e-36
Identities = 83/187 (44%), Positives = 113/187 (60%), Gaps = 21/187 (11%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVCA 64
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 65 AA-GLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDM 123
A G + A ++R+ ++ R + +G + LTVS+ ++ L
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNL-------------- 133
Query: 124 PRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEF 183
A+ D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++
Sbjct: 134 ----MAADCKQDTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQY 187
Query: 184 LTKPSTL 190
L P L
Sbjct: 188 LRNPPKL 194
>BC033925-1|AAH33925.1| 369|Homo sapiens SHC1 protein protein.
Length = 369
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 259 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 318
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 319 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 367
Score = 116 bits (279), Expect = 2e-25
Identities = 63/140 (45%), Positives = 83/140 (59%), Gaps = 8/140 (5%)
Query: 88 RPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSA 147
R + +G + LTVS+ ++ L + IA H M +SFASGGD D+ +YVAYVAK
Sbjct: 8 RSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKD- 66
Query: 148 PPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESACGLV 206
P RAC++LEC LAQDVI+TIGQAFELRFK++L P L + + + +
Sbjct: 67 -PVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDE 125
Query: 207 E-----DREYYNDMPDKVPP 221
E D +YYND P K PP
Sbjct: 126 EEEEPPDHQYYNDFPGKEPP 145
>AL451085-17|CAI13254.1| 384|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 384
Score = 128 bits (310), Expect = 3e-29
Identities = 64/109 (58%), Positives = 76/109 (69%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 274 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 333
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
LLLVDP GVVRTKD F+SV HLI YH N LPI+SA S L L++PV R
Sbjct: 334 LLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVER 382
Score = 117 bits (281), Expect = 9e-26
Identities = 63/144 (43%), Positives = 85/144 (59%), Gaps = 8/144 (5%)
Query: 84 ALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYV 143
++ R + +G + LTVS+ ++ L + IA H M +SFASGGD D+ +YVAYV
Sbjct: 19 SILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYV 78
Query: 144 AKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESA 202
AK P RAC++LEC LAQDVI+TIGQAFELRFK++L P L + + + +
Sbjct: 79 AKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGS 136
Query: 203 CGLVE-----DREYYNDMPDKVPP 221
E D +YYND P K PP
Sbjct: 137 AWDEEEEEPPDHQYYNDFPGKEPP 160
>AL360254-1|CAB96175.1| 392|Homo sapiens SCK protein.
Length = 392
Score = 122 bits (294), Expect = 2e-27
Identities = 69/160 (43%), Positives = 97/160 (60%), Gaps = 8/160 (5%)
Query: 67 GLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRV 126
G+R + KK+ ++A A L + + +G ++++ +S+ ++L+V IA H MP +
Sbjct: 2 GVRGSWKKKAPNKALASVL-GKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSI 60
Query: 127 SFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTK 186
SFASGGD D DYVAYVAK P RAC++LEC LAQ +I+T+GQAFELRFK++L
Sbjct: 61 SFASGGDTDMTDYVAYVAKD--PINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHS 118
Query: 187 PSTLNLNGSLPSC--ESACGLVED---REYYNDMPDKVPP 221
P + L + ESA G ED YYN +P K PP
Sbjct: 119 PPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPP 158
Score = 116 bits (279), Expect = 2e-25
Identities = 56/99 (56%), Positives = 71/99 (71%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L +EPW+HG +SR AE+++ DG+FLVR+S GQ+VLTG G KHLLLVDP GVV
Sbjct: 292 LRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV 351
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLR 415
RTKD +F+S+ HLI +H N PIV+A+S L LR V R
Sbjct: 352 RTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSR 390
>AY358250-1|AAQ88617.1| 387|Homo sapiens LPAL6438 protein.
Length = 387
Score = 119 bits (286), Expect = 2e-26
Identities = 56/102 (54%), Positives = 74/102 (72%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L E +HG +SR AE L+V+DG+FLVRES GQ+VL+G + G KHLLLVDP G V
Sbjct: 278 LWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKV 337
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRSSS 418
RTKD VFD+V HLI+YH N LPI+S+ S + L++PV + ++
Sbjct: 338 RTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNN 379
Score = 113 bits (271), Expect = 1e-24
Identities = 57/105 (54%), Positives = 69/105 (65%), Gaps = 3/105 (2%)
Query: 118 IARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFE 177
IA H M +SFASGGD D+ DYVAYVAK P RAC++LEC +AQDVI+TIGQAFE
Sbjct: 39 IANHHMQSISFASGGDPDTTDYVAYVAKD--PVNQRACHILECHNGMAQDVISTIGQAFE 96
Query: 178 LRFKEFLTKPS-TLNLNGSLPSCESACGLVEDREYYNDMPDKVPP 221
LRFK++L PS + +S ED EYYN++P K PP
Sbjct: 97 LRFKQYLKNPSLNTSCESEEVHIDSHAEEREDHEYYNEIPGKQPP 141
>AB208849-1|BAD92086.1| 377|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 1 isoform p66Shc va
protein.
Length = 377
Score = 116 bits (279), Expect = 2e-25
Identities = 63/140 (45%), Positives = 83/140 (59%), Gaps = 8/140 (5%)
Query: 88 RPRMSHSGANVALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSA 147
R + +G + LTVS+ ++ L + IA H M +SFASGGD D+ +YVAYVAK
Sbjct: 1 RSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKD- 59
Query: 148 PPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESACGLV 206
P RAC++LEC LAQDVI+TIGQAFELRFK++L P L + + + +
Sbjct: 60 -PVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDE 118
Query: 207 E-----DREYYNDMPDKVPP 221
E D +YYND P K PP
Sbjct: 119 EEEEPPDHQYYNDFPGKEPP 138
Score = 81.0 bits (191), Expect = 7e-15
Identities = 40/70 (57%), Positives = 48/70 (68%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 252 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 311
Query: 367 LLLVDPIGVV 376
LLLVDP GVV
Sbjct: 312 LLLVDPEGVV 321
>AL451085-10|CAI13247.1| 130|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 130
Score = 112 bits (270), Expect = 2e-24
Identities = 61/130 (46%), Positives = 79/130 (60%), Gaps = 8/130 (6%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ LTVS+ ++ L + IA H M +SFASGGD D+ +YVAYVAK P RAC++
Sbjct: 3 ITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKD--PVNQRACHI 60
Query: 158 LECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLNGSLPSCESACGLVE-----DREY 211
LEC LAQDVI+TIGQAFELRFK++L P L + + + + E D +Y
Sbjct: 61 LECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQY 120
Query: 212 YNDMPDKVPP 221
YND P K PP
Sbjct: 121 YNDFPGKEPP 130
>AL451085-16|CAI13253.1| 137|Homo sapiens SHC (Src homology 2
domain containing) transforming protein 1 protein.
Length = 137
Score = 103 bits (246), Expect = 2e-21
Identities = 47/106 (44%), Positives = 69/106 (65%), Gaps = 1/106 (0%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIARVC- 63
GSFV KP RGWLHP+ + GV+Y VRY+GC+EVL SM+ LDF+TR+QV +E I+ VC
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCE 87
Query: 64 AAAGLRSADKKRRVSQAAARALTARPRMSHSGANVALTVSSKAITL 109
A G + A ++R+ ++ R + +G + LTVS+ ++ L
Sbjct: 88 AVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNL 133
>AL451085-9|CAI13246.1| 200|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 1 protein.
Length = 200
Score = 81.4 bits (192), Expect = 5e-15
Identities = 45/93 (48%), Positives = 57/93 (61%), Gaps = 8/93 (8%)
Query: 135 DSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVIATIGQAFELRFKEFLTKPSTL-NLN 193
D+ +YVAYVAK P RAC++LEC LAQDVI+TIGQAFELRFK++L P L +
Sbjct: 22 DTAEYVAYVAKD--PVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPH 79
Query: 194 GSLPSCESACGLVE-----DREYYNDMPDKVPP 221
+ + + E D +YYND P K PP
Sbjct: 80 DRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPP 112
>AL451085-8|CAI13245.1| 296|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 1 protein.
Length = 296
Score = 79.4 bits (187), Expect = 2e-14
Identities = 39/69 (56%), Positives = 47/69 (68%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH 366
P + + A L EPWFHG +SR AE L+ +G+FLVREST GQ+VLTG + G KH
Sbjct: 136 PPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKH 195
Query: 367 LLLVDPIGV 375
LLLVDP GV
Sbjct: 196 LLLVDPEGV 204
>AL353150-1|CAI16864.1| 105|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 105
Score = 68.5 bits (160), Expect = 4e-11
Identities = 33/58 (56%), Positives = 39/58 (67%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L E W+ G +SR AE L+ +DG+FLVR+ST G FVLTG G KHLLLVDP G
Sbjct: 42 LQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEG 99
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 63.7 bits (148), Expect = 1e-09
Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
LA++ W+HG I R A++L+ + G+FLVRES G++VL+ G +H ++ +
Sbjct: 455 LAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMY 514
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
R + F ++P LI +H + + +++ S ++L P+
Sbjct: 515 RFEGTGFSNIPQLIDHHYTTK-QVITKKSGVVLLNPI 550
>U92715-1|AAC39777.1| 825|Homo sapiens breast cancer antiestrogen
resistance 3 protein protein.
Length = 825
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>BC039895-1|AAH39895.1| 825|Homo sapiens breast cancer
anti-estrogen resistance 3 protein.
Length = 825
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>AL359820-1|CAH73975.1| 825|Homo sapiens breast cancer
anti-estrogen resistance 3 protein.
Length = 825
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>AL109613-2|CAI18951.1| 734|Homo sapiens breast cancer
anti-estrogen resistance 3 protein.
Length = 734
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 58 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 117
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 118 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 165
>AL109613-1|CAI18950.1| 825|Homo sapiens breast cancer
anti-estrogen resistance 3 protein.
Length = 825
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>AF124250-1|AAD28245.1| 825|Homo sapiens SH2-containing protein
Nsp2 protein.
Length = 825
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/109 (34%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKH-------LLL 369
L W+HG I R +E LV DG+FLVR+S + G FVLT + L +H L L
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRL 208
Query: 370 VDPIGVVRTKDRV--FDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+ V+ + + FDS+P L++ + N PI S S ++ +P+ R+
Sbjct: 209 SEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPI-SQQSGAIIFQPINRT 256
>AY358406-1|AAQ88772.1| 576|Homo sapiens NSP1 protein.
Length = 576
Score = 57.2 bits (132), Expect = 1e-07
Identities = 35/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLV---- 370
LA +PW+HG +SR AE L+ +DG+FLVR S + G V++ RG LH + V
Sbjct: 10 LAGQPWYHGLLSRQKAEALLQQDGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRP 69
Query: 371 ---DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
P + + +D F S+P L+ + + P+ A A++ R
Sbjct: 70 RPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSR 112
>AF124249-1|AAD28244.1| 576|Homo sapiens SH2-containing protein
Nsp1 protein.
Length = 576
Score = 57.2 bits (132), Expect = 1e-07
Identities = 35/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLV---- 370
LA +PW+HG +SR AE L+ +DG+FLVR S + G V++ RG LH + V
Sbjct: 10 LAGQPWYHGLLSRQKAEALLQQDGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRP 69
Query: 371 ---DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
P + + +D F S+P L+ + + P+ A A++ R
Sbjct: 70 RPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSR 112
>BC006281-1|AAH06281.1| 576|Homo sapiens SH2 domain containing 3A
protein.
Length = 576
Score = 55.2 bits (127), Expect = 4e-07
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLV---- 370
LA +PW+HG +SR AE L+ ++G+FLVR S + G V++ RG LH + V
Sbjct: 10 LAGQPWYHGLLSRQKAEALLQQNGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRP 69
Query: 371 ---DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
P + + +D F S+P L+ + + P+ A A++ R
Sbjct: 70 RPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSR 112
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 54.8 bits (126), Expect = 5e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L ++ W+HG I R +L+V G+FLVRES ++VL+ GL +H ++ +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSGDFLVRESQG-KQEYVLSVLWDGLPRHFIIQSLDNLY 513
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
R + F S+P LI + S + P+ +L R
Sbjct: 514 RLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHR 547
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 54.8 bits (126), Expect = 5e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L ++ W+HG I R +L+V G+FLVRES ++VL+ GL +H ++ +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSGDFLVRESQG-KQEYVLSVLWDGLPRHFIIQSLDNLY 513
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
R + F S+P LI + S + P+ +L R
Sbjct: 514 RLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHR 547
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 54.8 bits (126), Expect = 5e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L ++ W+HG I R +L+V G+FLVRES ++VL+ GL +H ++ +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSGDFLVRESQG-KQEYVLSVLWDGLPRHFIIQSLDNLY 513
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
R + F S+P LI + S + P+ +L R
Sbjct: 514 RLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHR 547
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 54.8 bits (126), Expect = 5e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVV 376
L ++ W+HG I R +L+V G+FLVRES ++VL+ GL +H ++ +
Sbjct: 397 LHEQLWYHGAIPRAEVAELLVHSGDFLVRESQG-KQEYVLSVLWDGLPRHFIIQSLDNLY 455
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
R + F S+P LI + S + P+ +L R
Sbjct: 456 RLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHR 489
>AB000520-1|BAA22514.1| 632|Homo sapiens APS protein.
Length = 632
Score = 53.6 bits (123), Expect = 1e-06
Identities = 36/113 (31%), Positives = 62/113 (54%), Gaps = 7/113 (6%)
Query: 311 EAQAAL-LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARRGLH 364
EA+ L L+ PWFHG +SR A +LV+ G F++R+S G++VLT +G
Sbjct: 405 EAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKA 464
Query: 365 KHL-LLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
KHL L ++ G + F SV ++++ ++ +P+ S SA + + +R+
Sbjct: 465 KHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRA 517
>AJ012793-1|CAB42642.1| 576|Homo sapiens lymphocyte adaptor protein
(Lnk) protein.
Length = 576
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S G++VLT +G+ KHL L + G
Sbjct: 364 PWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG 423
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++ + + +P+
Sbjct: 424 QCRVQHLHFPSVVDMLHHFQRSPIPL 449
>AF055581-1|AAC71695.1| 575|Homo sapiens adaptor protein Lnk
protein.
Length = 575
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S G++VLT +G+ KHL L + G
Sbjct: 363 PWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG 422
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++ + + +P+
Sbjct: 423 QCRVQHLHFPSVVDMLHHFQRSPIPL 448
>AB208911-1|BAD92148.1| 439|Homo sapiens lymphocyte adaptor protein
variant protein.
Length = 439
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 321 PWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIG 374
PWFHGPISR A +LV G FLVR+S G++VLT +G+ KHL L + G
Sbjct: 227 PWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG 286
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPI 400
R + F SV ++ + + +P+
Sbjct: 287 QCRVQHLHFPSVVDMLHHFQRSPIPL 312
>BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 215 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 274
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 275 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 322
>BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein.
Length = 703
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 58 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 117
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 118 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 165
>AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein.
Length = 703
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 58 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 117
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 118 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 165
>AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein.
Length = 688
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 43 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 102
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 103 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 150
>AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 215 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 274
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 275 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 322
>AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3C
protein.
Length = 703
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 58 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 117
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 118 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 165
>AL162586-3|CAI39762.1| 324|Homo sapiens SH2 domain containing 3C
protein.
Length = 324
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 51 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 110
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 111 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 158
>AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3C
protein.
Length = 702
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 57 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 116
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 117 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 164
>AL162586-1|CAI39760.1| 196|Homo sapiens SH2 domain containing 3C
protein.
Length = 196
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 32 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 91
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 92 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 139
>AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3C
protein.
Length = 860
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 215 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 274
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 275 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 322
>AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3C
protein.
Length = 703
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 58 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 117
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 118 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 165
>AL162426-3|CAI41178.1| 324|Homo sapiens SH2 domain containing 3C
protein.
Length = 324
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 51 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 110
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 111 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 158
>AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3C
protein.
Length = 702
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 57 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 116
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 117 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 164
>AL162426-1|CAI41176.1| 196|Homo sapiens SH2 domain containing 3C
protein.
Length = 196
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 32 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 91
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 92 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 139
>AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein
Nsp3 protein.
Length = 703
Score = 52.0 bits (119), Expect = 4e-06
Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGEFLVRESTACAGQFVLTGARRGLHKHLLL---VDPI 373
L W+HG I R +E LV +G+FL+R+S G +VLT R H + V
Sbjct: 58 LRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKA 117
Query: 374 GVVRT------KDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
G T + FD VP L++YH + VS S ++ PV R+
Sbjct: 118 GESYTHIQYLFEQESFDHVPALVRYHVGSR-KAVSEQSGAIIYCPVNRT 165
>AL049924-1|CAB43208.1| 540|Homo sapiens hypothetical protein
protein.
Length = 540
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 379 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 438
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 439 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 474
>AK027488-1|BAB55148.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ14582 fis, clone NT2RM4001411, highly similar to
Mus musculus Pro-rich, PH, SH2 domain-containing
signaling ).
Length = 426
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 277 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 336
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 337 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 372
>AF227969-1|AAF73914.1| 683|Homo sapiens SH2-B gamma signaling
protein protein.
Length = 683
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 522 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 581
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 582 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 617
>AF227968-1|AAF73913.1| 671|Homo sapiens SH2-B beta signaling
protein protein.
Length = 671
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 522 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 581
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 582 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 617
>AF227967-1|AAF73912.1| 756|Homo sapiens SH2-B alpha signaling
protein protein.
Length = 756
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 522 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 581
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 582 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 617
>AB037720-1|BAA92537.1| 730|Homo sapiens KIAA1299 protein protein.
Length = 730
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVV-----EDGEFLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +LV+ G FLVR+S G++VLT +G KHL L +
Sbjct: 581 LSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 640
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 641 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 676
>X75342-1|CAA53091.1| 596|Homo sapiens Shb protein.
Length = 596
Score = 50.4 bits (115), Expect = 1e-05
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRG-LHKHLLL 369
A L K+ W+HG ISR AE L+ ++ +LVR S + L+ + +G +H L
Sbjct: 489 AVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYPLSLRSNQGFMHMKLAK 548
Query: 370 VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V+ FDSVP +I Y+ + +LPI A+ LL +R+
Sbjct: 549 TKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRT 595
>AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 1e-05
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRG-LHKHLLL 369
A L K+ W+HG ISR AE L+ ++ +LVR S + L+ + +G +H L
Sbjct: 402 AVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAK 461
Query: 370 VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V+ FDSVP +I Y+ + +LPI A+ LL +R+
Sbjct: 462 TKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRT 508
>AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 1e-05
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRG-LHKHLLL 369
A L K+ W+HG ISR AE L+ ++ +LVR S + L+ + +G +H L
Sbjct: 402 AVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAK 461
Query: 370 VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V+ FDSVP +I Y+ + +LPI A+ LL +R+
Sbjct: 462 TKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRT 508
>AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 1e-05
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLT-GARRG-LHKHLLL 369
A L K+ W+HG ISR AE L+ ++ +LVR S + L+ + +G +H L
Sbjct: 402 AVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAK 461
Query: 370 VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
V+ FDSVP +I Y+ + +LPI A+ LL +R+
Sbjct: 462 TKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRT 508
>BC010704-1|AAH10704.1| 426|Homo sapiens SH2B1 protein protein.
Length = 426
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Query: 317 LAKEPWFHGPISRTTAEKLVVEDGE-----FLVRESTACAGQFVLTGARRGLHKHL-LLV 370
L+ PWFHG +SR A +L + G FLVR+S G++VLT +G KHL L +
Sbjct: 277 LSGYPWFHGMLSRLKAAQLALTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSL 336
Query: 371 DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSA 406
+ G R + F S+ ++++ + +P+ S S+
Sbjct: 337 NEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSS 372
>AL390078-1|CAB98202.1| 247|Homo sapiens similar to (NP_033194.1)
src homology 2 domain-containing transforming protein
protein.
Length = 247
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKL--VVEDGEFLVR--ESTACAGQFVLTGARRGLH-KHLLLVD 371
L K+PWFHGP++R AE L + ++G +LVR E++ L ++ LH K +
Sbjct: 142 LEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRE 201
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
V+ F SVP L+ ++ S LP+ A+ LL
Sbjct: 202 NQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALL 239
>AK055673-1|BAB70981.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ31111 fis, clone IMR322000302, moderately
similar to Mus musculus shd mRNA. ).
Length = 340
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKL--VVEDGEFLVR--ESTACAGQFVLTGARRGLH-KHLLLVD 371
L K+PWFHGP++R AE L + ++G +LVR E++ L ++ LH K +
Sbjct: 235 LEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRE 294
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
V+ F SVP L+ ++ S LP+ A+ LL
Sbjct: 295 NQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALL 332
>BC007206-1|AAH07206.1| 340|Homo sapiens Src homology 2 domain
containing transforming protein D protein.
Length = 340
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/98 (33%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKL--VVEDGEFLVR--ESTACAGQFVLTGARRGLH-KHLLLVD 371
L K+PWFHGP++R AE L + ++G +LVR E+ L ++ LH K +
Sbjct: 235 LEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRE 294
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
V+ F SVP L+ ++ S LP+ A+ LL
Sbjct: 295 NQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALL 332
>BC007586-1|AAH07586.1| 233|Homo sapiens SHF protein protein.
Length = 233
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Query: 306 APLTAEAQAAL-LAKEPWFHGPISRTTAEKL--VVEDGEFLVRESTACAGQFVLT--GAR 360
+PL AL L + W+HG ISRT AE L + ++ +LVR S F L+ ++
Sbjct: 116 SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ 175
Query: 361 RGLHKHLLLV-DPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPVLRS 416
+H L + V+ F SVP ++ ++ S +LPI A+ LL +R+
Sbjct: 176 GFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 232
>BC117210-1|AAI17211.1| 495|Homo sapiens Src homology 2 domain
containing E protein.
Length = 495
Score = 48.0 bits (109), Expect = 6e-05
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV---D 371
L K+PW+HG ISR AE + ++ +LVR S + ++ + H+++ D
Sbjct: 390 LEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKD 449
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ VFDS+P ++ Y+ + +LP A+ LL
Sbjct: 450 NKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLL 487
>AL162591-2|CAH72851.1| 495|Homo sapiens Src homology 2 domain
containing E protein.
Length = 495
Score = 48.0 bits (109), Expect = 6e-05
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV---D 371
L K+PW+HG ISR AE + ++ +LVR S + ++ + H+++ D
Sbjct: 390 LEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKD 449
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ VFDS+P ++ Y+ + +LP A+ LL
Sbjct: 450 NKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLL 487
>AK074067-1|BAB84893.1| 309|Homo sapiens FLJ00138 protein protein.
Length = 309
Score = 48.0 bits (109), Expect = 6e-05
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLV---D 371
L K+PW+HG ISR AE + ++ +LVR S + ++ + H+++ D
Sbjct: 204 LEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKD 263
Query: 372 PIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ VFDS+P ++ Y+ + +LP A+ LL
Sbjct: 264 NKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLL 301
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L EPWF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L EPWF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L EPWF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L EPWF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 317 LAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
L+ PWFHG I+R AE+L+ E G FLVREST G + L + G +H ++
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 375 VVRTKDRV-FDSVPHLIKYHCSN 396
+ + V F+++ L++++ S+
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSD 159
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 181 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 240
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 241 GKVYVTAESRFSTLAELVHHH 261
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 153 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 212
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 213 GKVYVTAESRFSTLAELVHHH 233
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 153 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 212
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 213 GKVYVTAESRFSTLAELVHHH 233
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 153 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 212
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 213 GKVYVTAESRFSTLAELVHHH 233
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 168 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 227
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 228 GKVYVTAESRFSTLAELVHHH 248
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 45.2 bits (102), Expect = 4e-04
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 317 LAKEPWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRG--LHKHLLLVDP 372
L K W+HGP+SR+ AE L+ + +G FLVRES + GQ ++ G H +
Sbjct: 153 LEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTAD 212
Query: 373 IGVVRTKDRVFDSVPHLIKYH 393
V T + F ++ L+ +H
Sbjct: 213 GKVYVTAESRFSTLAELVHHH 233
>X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 44.8 bits (101), Expect = 6e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 319 KEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD-PIGV 375
+ W+ GP+SR A+ + G FLVR+S+ C G +VL+ + H ++ P
Sbjct: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70
Query: 376 VRTKDRVFDSVPHLIKYH 393
+ D+ FD +P L++++
Sbjct: 71 FKIGDQEFDHLPALLEFY 88
>CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 44.8 bits (101), Expect = 6e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 319 KEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD-PIGV 375
+ W+ GP+SR A+ + G FLVR+S+ C G +VL+ + H ++ P
Sbjct: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70
Query: 376 VRTKDRVFDSVPHLIKYH 393
+ D+ FD +P L++++
Sbjct: 71 FKIGDQEFDHLPALLEFY 88
>BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian)-like protein.
Length = 303
Score = 44.8 bits (101), Expect = 6e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 319 KEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVLTGARRGLHKHLLLVD-PIGV 375
+ W+ GP+SR A+ + G FLVR+S+ C G +VL+ + H ++ P
Sbjct: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70
Query: 376 VRTKDRVFDSVPHLIKYH 393
+ D+ FD +P L++++
Sbjct: 71 FKIGDQEFDHLPALLEFY 88
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 6/93 (6%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLTGARRG 362
P A+ L E WF G I R+ AEK ++ + G FL+RES + G+F L+
Sbjct: 101 PSNYVAEDRSLQAEAWFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 363 LHKHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
+ KH + +D G T+ R+F ++ + ++
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 193
>X83931-1|CAA58783.1| 539|Homo sapiens VAV protein.
Length = 539
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR-T 378
W+ GP+ R AE ++ DG FLVR+ A +F ++ KH+ ++ G+ R T
Sbjct: 373 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRIT 432
Query: 379 KDRVFDSVPHLIKYHCSNEL 398
+ + F + L++++ N L
Sbjct: 433 EKKAFRGLTELVEFYQQNSL 452
>BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein.
Length = 790
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR-T 378
W+ GP+ R AE ++ DG FLVR+ A +F ++ KH+ ++ G+ R T
Sbjct: 616 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRIT 675
Query: 379 KDRVFDSVPHLIKYHCSNEL 398
+ + F + L++++ N L
Sbjct: 676 EKKAFRGLTELVEFYQQNSL 695
>AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric
protein protein.
Length = 498
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 374 LEKHSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQ 412
>AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein.
Length = 845
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIGVVR-T 378
W+ GP+ R AE ++ DG FLVR+ A +F ++ KH+ ++ G+ R T
Sbjct: 671 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRIT 730
Query: 379 KDRVFDSVPHLIKYHCSNEL 398
+ + F + L++++ N L
Sbjct: 731 EKKAFRGLTELVEFYQQNSL 750
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 122 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 160
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 122 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 160
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 141 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 179
>L76687-1|AAC15861.1| 540|Homo sapiens Grb14 protein.
Length = 540
Score = 42.3 bits (95), Expect = 0.003
Identities = 22/60 (36%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
A+ +PWFH ISR A++L+++ DG FLVR+S + FVL+ + KH ++
Sbjct: 432 AIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQII 491
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 141 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 179
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 141 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 179
>BC053559-1|AAH53559.1| 540|Homo sapiens growth factor
receptor-bound protein 14 protein.
Length = 540
Score = 42.3 bits (95), Expect = 0.003
Identities = 22/60 (36%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
A+ +PWFH ISR A++L+++ DG FLVR+S + FVL+ + KH ++
Sbjct: 432 AIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQII 491
>AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric
protein protein.
Length = 585
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 461 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 499
>AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric
protein protein.
Length = 313
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 189 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 227
>AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric
protein protein.
Length = 260
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 136 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 174
>AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric
protein protein.
Length = 235
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 111 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 149
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 141 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 179
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 141 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 179
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 122 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 160
>AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion
peptide protein.
Length = 307
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 195 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 233
>AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoint)
fusion peptide protein.
Length = 332
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 220 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 258
>AF455141-2|AAM61860.1| 55|Homo sapiens Src homology 2
domain-containing transforming protein 1 isoform p52
protein.
Length = 55
Score = 42.3 bits (95), Expect = 0.003
Identities = 17/28 (60%), Positives = 20/28 (71%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVR 32
GSFV KP RGWLHP+ + GV+Y VR
Sbjct: 28 GSFVNKPTRGWLHPNDKVMGPGVSYLVR 55
>AF455141-1|AAM61859.1| 165|Homo sapiens Src homology 2
domain-containing transforming protein 1 isoform p66
protein.
Length = 165
Score = 42.3 bits (95), Expect = 0.003
Identities = 17/28 (60%), Positives = 20/28 (71%)
Query: 5 GSFVAKPARGWLHPDSVLASDGVTYAVR 32
GSFV KP RGWLHP+ + GV+Y VR
Sbjct: 138 GSFVNKPTRGWLHPNDKVMGPGVSYLVR 165
>AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoint
peptide protein.
Length = 359
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 247 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 285
>AC110086-1|AAY24176.1| 172|Homo sapiens unknown protein.
Length = 172
Score = 42.3 bits (95), Expect = 0.003
Identities = 22/60 (36%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 315 ALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
A+ +PWFH ISR A++L+++ DG FLVR+S + FVL+ + KH ++
Sbjct: 64 AIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQII 123
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE L+ +G FLVRES + GQ
Sbjct: 159 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ 197
>X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein.
Length = 160
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 2 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 61
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 62 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 92
>M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor
receptor-binding protein GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein
phosphatase protein.
Length = 593
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine
phosphatase, non-receptor type 11 (Noonan syndrome 1)
protein.
Length = 460
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein.
Length = 460
Score = 41.9 bits (94), Expect = 0.004
Identities = 22/41 (53%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E WFHG +S AEKL+ E G+ FLVRES + G FVL+
Sbjct: 110 ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLS 150
Score = 35.1 bits (77), Expect = 0.46
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL 367
WFH I+ AE L++ DG FL R S + G F L+ R G H+
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI 54
>BC000631-1|AAH00631.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 41.9 bits (94), Expect = 0.004
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 307 PLT--AEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT--G 358
P+T A+A L+ +PW+ +SRT A++L++ E G FL+R S + G + L+
Sbjct: 103 PITHVAKASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRA 162
Query: 359 ARRGLHKHLLLVDPIGVVRTKDRVFDSVPHLIKYHCSN 396
+ H + + + K R+F + L+ Y+ +N
Sbjct: 163 QAKVCHYRVSMAADGSLYLQKGRLFPGLEELLTYYKAN 200
>AF498925-1|AAM21073.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>AF063618-1|AAC72075.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.004
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 321 PWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHL-LLVDPIGVV 376
PWF G I R AE+++ + DG FL+RES + G F L+ +H +L D G
Sbjct: 59 PWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY 118
Query: 377 RTKDRVFDSVPHLIKYHCSNELPIVSADSALLLR 410
F+S+ L+ YH S VS + + LR
Sbjct: 119 FLWVVKFNSLNELVDYHRSTS---VSRNQQIFLR 149
>M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human
phospholipase C-gamma mRNA, complete cds. ).
Length = 1290
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 652
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 653 LSEPVPQTNA 662
>DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 652
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 653 LSEPVPQTNA 662
>AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1290
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 652
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 653 LSEPVPQTNA 662
>AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 652
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 653 LSEPVPQTNA 662
>AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein
protein.
Length = 1412
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 307 PLTAEAQAALLAKEPWFHGPIS-----RTTAEKLVVE--------DGEFLVRESTACAGQ 353
P + L + E WFHG + R AE+L+ E DG FLVRES G
Sbjct: 657 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 716
Query: 354 FVLTGARRGLHKHLLL--VDPIGVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALL 408
+ L+ R G +H + G + T + VFDS+ LI ++ ++P+ + +
Sbjct: 717 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY--QQVPLRCNEFEMR 774
Query: 409 LRKPVLRSSS 418
L +PV ++++
Sbjct: 775 LSEPVPQTNA 784
>Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate
5-phosphatase protein.
Length = 1258
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 315 ALLAKEP-WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGA-RRGLHKHLLL 369
AL ++ P W+H +SR AE+L+ DG FLVR+S + AG F L ++ +H + +L
Sbjct: 13 ALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRIL 72
Query: 370 VD 371
D
Sbjct: 73 PD 74
>X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma
mRNA for nck protein, showing homology to src. ).
Length = 377
Score = 39.9 bits (89), Expect = 0.016
Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 318 AKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
A PW++G ++R AE + E +G+FL+R+S + F ++ +G +KH +
Sbjct: 278 AGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKET 337
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
V R F ++ L++++ + PI +++
Sbjct: 338 VYCIGQRKFSTMEELVEHY--KKAPIFTSE 365
>M23612-1|AAA35865.1| 870|Homo sapiens GTPase-activating protein
protein.
Length = 870
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 64 IGGRRFSSLSDLIGYY 79
>M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein
protein.
Length = 1047
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 181 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 240
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 241 IGGRRFSSLSDLIGYY 256
>BC054891-1|AAH54891.1| 313|Homo sapiens RASA1 protein protein.
Length = 313
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 64 IGGRRFSSLSDLIGYY 79
>BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activator
(GTPase activating protein) 1 protein.
Length = 1047
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 181 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 240
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 241 IGGRRFSSLSDLIGYY 256
>BC020761-1|AAH20761.1| 317|Homo sapiens Unknown (protein for
IMAGE:4733187) protein.
Length = 317
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 64 IGGRRFSSLSDLIGYY 79
>BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.016
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKH 366
++ +A LL W+HG ++R AE L++ DG +L+R+S G + L+ + KH
Sbjct: 23 SDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ + F S+ +K H +N+ P++ +++ L+
Sbjct: 83 FHVEYTGYSFKFGFNEFSSLKDFVK-HFANQ-PLIGSETGTLM 123
>BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1
protein.
Length = 377
Score = 39.9 bits (89), Expect = 0.016
Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 318 AKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
A PW++G ++R AE + E +G+FL+R+S + F ++ +G +KH +
Sbjct: 278 AGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKET 337
Query: 375 VVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
V R F ++ L++++ + PI +++
Sbjct: 338 VYCIGQRKFSTMEELVEHY--KKAPIFTSE 365
>AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter
protein BAM32 protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.016
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKH 366
++ +A LL W+HG ++R AE L++ DG +L+R+S G + L+ + KH
Sbjct: 23 SDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ + F S+ +K H +N+ P++ +++ L+
Sbjct: 83 FHVEYTGYSFKFGFNEFSSLKDFVK-HFANQ-PLIGSETGTLM 123
>AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine
phosphatase D protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.016
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKH 366
++ +A LL W+HG ++R AE L++ DG +L+R+S G + L+ + KH
Sbjct: 23 SDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ + F S+ +K H +N+ P++ +++ L+
Sbjct: 83 FHVEYTGYSFKFGFNEFSSLKDFVK-HFANQ-PLIGSETGTLM 123
>AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1
protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.016
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 310 AEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHKH 366
++ +A LL W+HG ++R AE L++ DG +L+R+S G + L+ + KH
Sbjct: 23 SDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
Query: 367 LLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
+ + F S+ +K H +N+ P++ +++ L+
Sbjct: 83 FHVEYTGYSFKFGFNEFSSLKDFVK-HFANQ-PLIGSETGTLM 123
>AF047348-1|AAC39767.1| 748|Homo sapiens adaptor protein X11beta
protein.
Length = 748
Score = 39.9 bits (89), Expect = 0.016
Identities = 58/225 (25%), Positives = 99/225 (44%), Gaps = 28/225 (12%)
Query: 1 MAESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIA 60
+A SFVA P G P+ ++ DG+ +A Y+G ++L S + + R A+E ++
Sbjct: 347 VASFPSFVAVP--GPCEPEDLI--DGIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVS 401
Query: 61 RVCAAAGLRSADKKRRVSQAAARALT------ARPRMSHSGANVALTVSSKAI-TLA-VL 112
RV KK S+ A+ LT + R+ A+ T+ A+ T++ +
Sbjct: 402 RVKRMQKAAKIKKKAN-SEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIA 460
Query: 113 EGGDTI---ARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVI 169
+ G+ + AR MPR D ++ A+ C+V E AQ +
Sbjct: 461 DIGNIVVLMARRRMPR-----SASQDCIETTPG-AQEGKKQYKMICHVFESED--AQLIA 512
Query: 170 ATIGQAFELRFKEFLTKPSTLNLNGSLPSCESACGLVEDREYYND 214
+IGQAF + ++EFL +N S + ++ +E YND
Sbjct: 513 QSIGQAFSVAYQEFL---RANGINPEDLSQKEYSDIINTQEMYND 554
>AB209281-1|BAD92518.1| 752|Homo sapiens amyloid beta A4 precursor
protein-binding, family A, member 2 variant protein.
Length = 752
Score = 39.9 bits (89), Expect = 0.016
Identities = 58/225 (25%), Positives = 99/225 (44%), Gaps = 28/225 (12%)
Query: 1 MAESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIA 60
+A SFVA P G P+ ++ DG+ +A Y+G ++L S + + R A+E ++
Sbjct: 351 VASFPSFVAVP--GPCEPEDLI--DGIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVS 405
Query: 61 RVCAAAGLRSADKKRRVSQAAARALT------ARPRMSHSGANVALTVSSKAI-TLA-VL 112
RV KK S+ A+ LT + R+ A+ T+ A+ T++ +
Sbjct: 406 RVKRMQKAAKIKKKAN-SEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIA 464
Query: 113 EGGDTI---ARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVI 169
+ G+ + AR MPR D ++ A+ C+V E AQ +
Sbjct: 465 DIGNIVVLMARRRMPR-----SASQDCIETTPG-AQEGKKQYKMICHVFESED--AQLIA 516
Query: 170 ATIGQAFELRFKEFLTKPSTLNLNGSLPSCESACGLVEDREYYND 214
+IGQAF + ++EFL +N S + ++ +E YND
Sbjct: 517 QSIGQAFSVAYQEFL---RANGINPEDLSQKEYSDIINTQEMYND 558
>AB209106-1|BAD92343.1| 871|Homo sapiens RAS p21 protein activator
1 isoform 1 variant protein.
Length = 871
Score = 39.9 bits (89), Expect = 0.016
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 322 WFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTG-ARRGLHKHLLLVDPIGVVR 377
W+HG + RT AE+ + + G +L+RES G FVL+ ++ + H ++ G
Sbjct: 214 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 273
Query: 378 TKDRVFDSVPHLIKYH 393
R F S+ LI Y+
Sbjct: 274 IGGRRFSSLSDLIGYY 289
>BC068451-1|AAH68451.1| 357|Homo sapiens ANKS1B protein protein.
Length = 357
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 203 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 260
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 261 FTAFDVNLAYEIILTLGQAFEVAYQ 285
>BC026313-1|AAH26313.2| 510|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1B protein.
Length = 510
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 355 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 412
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 413 FTAFDVNLAYEIILTLGQAFEVAYQ 437
>AY753193-1|AAV28691.1| 426|Homo sapiens AIDA1C transcript variant
4 protein.
Length = 426
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 271 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 328
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 329 FTAFDVNLAYEIILTLGQAFEVAYQ 353
>AY620824-1|AAT39519.1| 768|Homo sapiens AIDA-1bDelta Ank-2
protein.
Length = 768
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 681 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 738
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 739 FTAFDVNLAYEIILTLGQAFEVAYQ 763
>AY356353-1|AAQ56189.1| 366|Homo sapiens cajalin 2 protein.
Length = 366
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 211 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 268
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 269 FTAFDVNLAYEIILTLGQAFEVAYQ 293
>AY283057-1|AAP38184.2| 750|Homo sapiens AIDA-1bDAnk protein.
Length = 750
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 607 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 664
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 665 FTAFDVNLAYEIILTLGQAFEVAYQ 689
>AY281132-1|AAP37613.1| 460|Homo sapiens AIDA-1a protein.
Length = 460
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 331 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 388
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 389 FTAFDVNLAYEIILTLGQAFEVAYQ 413
>AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein.
Length = 1249
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 1106 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 1163
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 1164 FTAFDVNLAYEIILTLGQAFEVAYQ 1188
>AF164792-1|AAF80756.1| 414|Homo sapiens putative 47 kDa protein
protein.
Length = 414
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 271 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 328
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 329 FTAFDVNLAYEIILTLGQAFEVAYQ 353
>AF145204-1|AAD33951.1| 955|Homo sapiens E2a-Pbx1-associated
protein protein.
Length = 955
Score = 39.5 bits (88), Expect = 0.022
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+VS K + + IA H++ +S A+ D + L AY+ K C+V
Sbjct: 812 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQ-DPEDLSTFAYITKDLKSNH-HYCHV 869
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
LA ++I T+GQAFE+ ++
Sbjct: 870 FTAFDVNLAYEIILTLGQAFEVAYQ 894
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein.
Length = 363
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>D43772-1|BAA07827.1| 532|Homo sapiens GRB-7 SH2 domain protein
protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>BT006686-1|AAP35332.1| 532|Homo sapiens growth factor
receptor-bound protein 7 protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 112 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
>BC006535-1|AAH06535.1| 532|Homo sapiens growth factor
receptor-bound protein 7 protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 526
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 99 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 99 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
>AK222870-1|BAD96590.1| 532|Homo sapiens growth factor
receptor-bound protein 7 variant protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>AK222849-1|BAD96569.1| 532|Homo sapiens growth factor
receptor-bound protein 7 variant protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 170 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 224
>AF274875-1|AAG25938.1| 532|Homo sapiens growth factor
receptor-bound protein 7 protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 38.7 bits (86), Expect = 0.038
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Query: 307 PLTAEAQAALLAKEPWFHGPISRTTAEKLVV----EDGEFLVRESTACAGQFVLT 357
P A+A L EPWF +SR AE+ ++ G FL+RES + AG F L+
Sbjct: 99 PFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
>AB008789-1|BAA29059.1| 532|Homo sapiens grb7 protein protein.
Length = 532
Score = 38.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 314 AALLAKEPWFHGPISRTTAEKLV----VEDGEFLVRESTACAGQFVLTGARRGLHKHLLL 369
AA+ + WFHG ISR +++L+ + DG FLVRES FVL+ KH L+
Sbjct: 423 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI 482
Query: 370 V 370
+
Sbjct: 483 L 483
>X16316-1|CAA34383.1| 797|Homo sapiens VAV protein.
Length = 797
Score = 38.3 bits (85), Expect = 0.050
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 322 WFHGPISRTTAEKLVVE--DGEFLVRESTACAGQFVLTGARRGLHKHLL-LVDPIGVVR- 377
W+ GP+ R AE ++ DG FLVR+ A +F ++ KH + ++ G+ R
Sbjct: 622 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHTVKIMTAEGLYRI 681
Query: 378 TKDRVFDSVPHLIKYHCSNEL 398
T+ + F + L++++ N L
Sbjct: 682 TEKKAFRGLTELVEFYQQNSL 702
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 38.3 bits (85), Expect = 0.050
Identities = 27/65 (41%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL--TGARRGL 363
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL T R +
Sbjct: 70 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESGGHPGDYVLCVTFGRDVI 126
Query: 364 HKHLL 368
H +L
Sbjct: 127 HYRVL 131
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 37.9 bits (84), Expect = 0.066
Identities = 26/94 (27%), Positives = 53/94 (56%), Gaps = 12/94 (12%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLV 370
E W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 277 EMWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVC 335
Query: 371 D-PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 336 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 369
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 37.9 bits (84), Expect = 0.066
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 308 LTAEAQAALLAKEPWFHGPISRTTAEKLVV--EDGEFLVRESTACAGQFVL 356
L+A+ + +L+ PWFHG IS A + + EDG FLVRES G +VL
Sbjct: 111 LSADPKLSLM---PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVL 158
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 1027 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1084
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1085 FSTVDVNLTYEIILTLGQAFEVAYQ 1109
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 981 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1038
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1039 FSTVDVNLTYEIILTLGQAFEVAYQ 1063
>BC049213-1|AAH49213.1| 460|Homo sapiens ANKS1A protein protein.
Length = 460
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 307 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 364
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 365 FSTVDVNLTYEIILTLGQAFEVAYQ 389
>BC031934-1|AAH31934.1| 570|Homo sapiens ANKS1A protein protein.
Length = 570
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 307 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 364
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 365 FSTVDVNLTYEIILTLGQAFEVAYQ 389
>BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 37.5 bits (83), Expect = 0.087
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 320 EPWFHGPIS-RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
E WFH + RT+AEKL+ E DG FLVRES + L+ R G +H +
Sbjct: 530 EKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIR 589
Query: 371 DPI--GVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G ++ T + F S+ LI+++ E + A+ L L PV
Sbjct: 590 STMEGGTLKYYLTDNLTFSSIYALIQHY--RETHLRCAEFELRLTDPV 635
Score = 34.7 bits (76), Expect = 0.61
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 320 EPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
+PW++ +SR AE +++ DG FL+R+ + + +T RG KH + D
Sbjct: 644 KPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREG-SDSYAITFRARGKVKHCRINRDGRHF 702
Query: 376 VRTKDRVFDSVPHLIKYHCSNEL 398
V F+S+ L+ Y+ + L
Sbjct: 703 VLGTSAYFESLVELVSYYEKHSL 725
>BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 37.5 bits (83), Expect = 0.087
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 320 EPWFHGPIS-RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
E WFH + RT+AEKL+ E DG FLVRES + L+ R G +H +
Sbjct: 530 EKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIR 589
Query: 371 DPI--GVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G ++ T + F S+ LI+++ E + A+ L L PV
Sbjct: 590 STMEGGTLKYYLTDNLTFSSIYALIQHY--RETHLRCAEFELRLTDPV 635
Score = 34.7 bits (76), Expect = 0.61
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 320 EPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
+PW++ +SR AE +++ DG FL+R+ + + +T RG KH + D
Sbjct: 644 KPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREG-SDSYAITFRARGKVKHCRINRDGRHF 702
Query: 376 VRTKDRVFDSVPHLIKYHCSNEL 398
V F+S+ L+ Y+ + L
Sbjct: 703 VLGTSAYFESLVELVSYYEKHSL 725
>BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 37.5 bits (83), Expect = 0.087
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 320 EPWFHGPIS-RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
E WFH + RT+AEKL+ E DG FLVRES + L+ R G +H +
Sbjct: 530 EKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIR 589
Query: 371 DPI--GVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G ++ T + F S+ LI+++ E + A+ L L PV
Sbjct: 590 STMEGGTLKYYLTDNLTFSSIYALIQHY--RETHLRCAEFELRLTDPV 635
Score = 34.7 bits (76), Expect = 0.61
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 320 EPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
+PW++ +SR AE +++ DG FL+R+ + + +T RG KH + D
Sbjct: 644 KPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREG-SDSYAITFRARGKVKHCRINRDGRHF 702
Query: 376 VRTKDRVFDSVPHLIKYHCSNEL 398
V F+S+ L+ Y+ + L
Sbjct: 703 VLGTSAYFESLVELVSYYEKHSL 725
>BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 37.5 bits (83), Expect = 0.087
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 320 EPWFHGPIS-RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
E WFH + RT+AEKL+ E DG FLVRES + L+ R G +H +
Sbjct: 530 EKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIR 589
Query: 371 DPI--GVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G ++ T + F S+ LI+++ E + A+ L L PV
Sbjct: 590 STMEGGTLKYYLTDNLTFSSIYALIQHY--RETHLRCAEFELRLTDPV 635
Score = 34.7 bits (76), Expect = 0.61
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 320 EPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
+PW++ +SR AE +++ DG FL+R+ + + +T RG KH + D
Sbjct: 644 KPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREG-SDSYAITFRARGKVKHCRINRDGRHF 702
Query: 376 VRTKDRVFDSVPHLIKYHCSNEL 398
V F+S+ L+ Y+ + L
Sbjct: 703 VLGTSAYFESLVELVSYYEKHSL 725
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 981 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1038
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1039 FSTVDVNLTYEIILTLGQAFEVAYQ 1063
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 981 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1038
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1039 FSTVDVNLTYEIILTLGQAFEVAYQ 1063
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 37.5 bits (83), Expect = 0.087
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 98 VALTVSSKAITLAVLEGGDTIARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYV 157
+ L+++ K + + IA H++ +S A+ D + L AY+ K T C+V
Sbjct: 981 IILSITYKGVKFIDASNKNVIAEHEIRNISCAAQ-DPEDLCTFAYITKDLQ-TSHHYCHV 1038
Query: 158 LECGG-RLAQDVIATIGQAFELRFK 181
L ++I T+GQAFE+ ++
Sbjct: 1039 FSTVDVNLTYEIILTLGQAFEVAYQ 1063
>AB208914-1|BAD92151.1| 1278|Homo sapiens
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma 2 variant protein.
Length = 1278
Score = 37.5 bits (83), Expect = 0.087
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 320 EPWFHGPIS-RTTAEKLVVE--------DGEFLVRESTACAGQFVLTGARRGLHKHLLLV 370
E WFH + RT+AEKL+ E DG FLVRES + L+ R G +H +
Sbjct: 543 EKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIR 602
Query: 371 DPI--GVVR---TKDRVFDSVPHLIKYHCSNELPIVSADSALLLRKPV 413
+ G ++ T + F S+ LI+++ E + A+ L L PV
Sbjct: 603 STMEGGTLKYYLTDNLTFSSIYALIQHY--RETHLRCAEFELRLTDPV 648
Score = 34.7 bits (76), Expect = 0.61
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 320 EPWFHGPISRTTAEKLVV---EDGEFLVRESTACAGQFVLTGARRGLHKHLLL-VDPIGV 375
+PW++ +SR AE +++ DG FL+R+ + + +T RG KH + D
Sbjct: 657 KPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREG-SDSYAITFRARGKVKHCRINRDGRHF 715
Query: 376 VRTKDRVFDSVPHLIKYHCSNEL 398
V F+S+ L+ Y+ + L
Sbjct: 716 VLGTSAYFESLVELVSYYEKHSL 738
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 37.1 bits (82), Expect = 0.12
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 317 LAKEPWFHGPISRTTAEKLVVE--DGEFLVRESTACAGQ 353
L K W+HGP+SR AE + +G FLVRES + Q
Sbjct: 122 LEKHSWYHGPVSRNAAEYPLSSGINGSFLVRESESSPSQ 160
>BC026233-1|AAH26233.1| 64|Homo sapiens LOC400581 protein protein.
Length = 64
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 321 PWFHGPISRTTAEKLVVED---GEFLVRESTACAGQF-VLTGARRG 362
PW+ G ISR AE+++++ G FL+RES + G+F V A+RG
Sbjct: 7 PWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVKAQRG 52
>BC020082-1|AAH20082.1| 535|Homo sapiens suppressor of cytokine
signaling 6 protein.
Length = 535
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/34 (58%), Positives = 25/34 (73%), Gaps = 2/34 (5%)
Query: 317 LAKEPWFHGPISRTTAE-KLV-VEDGEFLVREST 348
LAK+ W+ GPI+R AE KL V DG FLVR+S+
Sbjct: 379 LAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSS 412
>AL731544-3|CAI14998.1| 431|Homo sapiens novel SH2
domain-containing protein protein.
Length = 431
Score = 37.1 bits (82), Expect = 0.12
Identities = 25/56 (44%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 321 PWFHGPISRTTAEKLV--VEDGEFLVRESTACAGQFVLTGARRGLHKHLLLVDPIG 374
PWFHG ISR AE L+ + +G FLVR S G + ++G KH LVD G
Sbjct: 324 PWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGF-KH-FLVDASG 377
>AB006968-1|BAA22538.1| 535|Homo sapiens CIS4 protein.
Length = 535
Score = 37.1 bits (82), Expect = 0.12
Identities = 20/34 (58%), Positives = 25/34 (73%), Gaps = 2/34 (5%)
Query: 317 LAKEPWFHGPISRTTAE-KLV-VEDGEFLVREST 348
LAK+ W+ GPI+R AE KL V DG FLVR+S+
Sbjct: 379 LAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSS 412
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 36.7 bits (81), Expect = 0.15
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 12/92 (13%)
Query: 322 WFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVL------TGARRGLHKHLLLVD- 371
W+ ++R+ AE+L+ ++G+ F+VR+S+ AG++ + TG +G+ +H ++
Sbjct: 281 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGDPQGVIRHYVVCST 339
Query: 372 PIGVVRTKDR-VFDSVPHLIKYHCSNELPIVS 402
P ++ +F ++P LI YH N ++S
Sbjct: 340 PQSQYYLAEKHLFSTIPELINYHQHNSAGLIS 371
>AB014719-1|BAA34734.1| 749|Homo sapiens XllL protein.
Length = 749
Score = 36.7 bits (81), Expect = 0.15
Identities = 57/225 (25%), Positives = 98/225 (43%), Gaps = 28/225 (12%)
Query: 1 MAESGSFVAKPARGWLHPDSVLASDGVTYAVRYIGCMEVLTSMKKLDFDTRSQVAKECIA 60
+A S VA P G P +++ DG+ +A Y+G ++L S + + R A+E ++
Sbjct: 348 VASFPSLVAVP--GPCEPKNLI--DGIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVS 402
Query: 61 RVCAAAGLRSADKKRRVSQAAARALT------ARPRMSHSGANVALTVSSKAI-TLA-VL 112
RV KK S+ A+ LT + R+ A+ T+ A+ T++ +
Sbjct: 403 RVKRMQKAAKIKKKAN-SEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIA 461
Query: 113 EGGDTI---ARHDMPRVSFASGGDADSLDYVAYVAKSAPPTEWRACYVLECGGRLAQDVI 169
+ G+ + AR MPR D ++ A+ C+V E AQ +
Sbjct: 462 DIGNIVVLMARRRMPR-----SASQDCIETTPG-AQEGKKQYKMICHVFESED--AQLIA 513
Query: 170 ATIGQAFELRFKEFLTKPSTLNLNGSLPSCESACGLVEDREYYND 214
+IGQAF + ++EFL +N S + ++ +E YND
Sbjct: 514 QSIGQAFSVAYQEFL---RANGINPEDLSQKEYSDIINTQEMYND 555
>BC082982-1|AAH82982.1| 454|Homo sapiens SH2D4A protein protein.
Length = 454
Score = 36.3 bits (80), Expect = 0.20
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
E PL A Q PWFHG ++ A +L++ G FL+R S G + L+
Sbjct: 329 EQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLS 387
Query: 361 RGLHKHLLL---VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
KH L+ D + ++ L++YH E PI S LLL
Sbjct: 388 EDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYH--KEEPITSLGKELLL 437
>BC014525-1|AAH14525.2| 338|Homo sapiens SH2D4A protein protein.
Length = 338
Score = 36.3 bits (80), Expect = 0.20
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
E PL A Q PWFHG ++ A +L++ G FL+R S G + L+
Sbjct: 213 EQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLS 271
Query: 361 RGLHKHLLL---VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
KH L+ D + ++ L++YH E PI S LLL
Sbjct: 272 EDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYH--KEEPITSLGKELLL 321
>AK024799-1|BAB15010.1| 454|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21146 fis, clone CAS09305. ).
Length = 454
Score = 36.3 bits (80), Expect = 0.20
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
E PL A Q PWFHG ++ A +L++ G FL+R S G + L+
Sbjct: 329 EQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLS 387
Query: 361 RGLHKHLLL---VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
KH L+ D + ++ L++YH E PI S LLL
Sbjct: 388 EDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYH--KEEPITSLGKELLL 437
>AK024620-1|BAB14935.1| 272|Homo sapiens protein ( Homo sapiens
cDNA: FLJ20967 fis, clone ADSH01731. ).
Length = 272
Score = 36.3 bits (80), Expect = 0.20
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 304 ECAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGAR 360
E PL A Q PWFHG ++ A +L++ G FL+R S G + L+
Sbjct: 147 EQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLS 205
Query: 361 RGLHKHLLL---VDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSADSALLL 409
KH L+ D + ++ L++YH E PI S LLL
Sbjct: 206 EDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYH--KEEPITSLGKELLL 255
>X62055-1|CAA43982.1| 597|Homo sapiens protein-tyrosine
phosphatase 1C protein.
Length = 597
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 110 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 150
>U47924-18|AAB51323.1| 595|Homo sapiens protein tyrosine
phosphatase 1C protein.
Length = 595
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>U47924-17|AAB51322.1| 556|Homo sapiens protein tyrosine
phosphatase 1C protein.
Length = 556
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 69 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 109
>M77273-1|AAA36610.1| 595|Homo sapiens tyrosine phosphatase
protein.
Length = 595
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>M74903-1|AAA35963.1| 595|Homo sapiens hematopoietic cell
phophatase protein.
Length = 595
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 35.9 bits (79), Expect = 0.27
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 305 CAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT--- 357
C P A + E W+ G I R AE+ ++ G FL+RES G + L+
Sbjct: 127 CIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
Query: 358 -GARRGLH-KHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
RG H KH + +D G T F+SV L++++
Sbjct: 187 WDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHY 226
>M12724-1|AAA52762.1| 306|Homo sapiens FGR protein.
Length = 306
Score = 35.9 bits (79), Expect = 0.27
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 305 CAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT--- 357
C P A + E W+ G I R AE+ ++ G FL+RES G + L+
Sbjct: 17 CIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 76
Query: 358 -GARRGLH-KHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
RG H KH + +D G T F+SV L++++
Sbjct: 77 WDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHY 116
>BT007390-1|AAP36054.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 110 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 150
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 35.9 bits (79), Expect = 0.27
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 305 CAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT--- 357
C P A + E W+ G I R AE+ ++ G FL+RES G + L+
Sbjct: 127 CIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
Query: 358 -GARRGLH-KHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
RG H KH + +D G T F+SV L++++
Sbjct: 187 WDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHY 226
>BC007667-1|AAH07667.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 110 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 150
>BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 35.9 bits (79), Expect = 0.27
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHK 365
T + + A W++G ++R AE + E +G+FL+R+S + F ++ G +K
Sbjct: 272 TGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNK 331
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
H + V R F ++ L++++ + PI +++
Sbjct: 332 HFKVQLVDNVYCIGQRRFHTMDELVEHY--KKAPIFTSE 368
>BC002523-1|AAH02523.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 110 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 150
>BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 35.9 bits (79), Expect = 0.27
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHK 365
T + + A W++G ++R AE + E +G+FL+R+S + F ++ G +K
Sbjct: 272 TGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNK 331
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
H + V R F ++ L++++ + PI +++
Sbjct: 332 HFKVQLVDNVYCIGQRRFHTMDELVEHY--KKAPIFTSE 368
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 35.9 bits (79), Expect = 0.27
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 305 CAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT--- 357
C P A + E W+ G I R AE+ ++ G FL+RES G + L+
Sbjct: 127 CIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
Query: 358 -GARRGLH-KHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
RG H KH + +D G T F+SV L++++
Sbjct: 187 WDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHY 226
>AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 313
Score = 35.9 bits (79), Expect = 0.27
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 305 CAPLTAEAQAALLAKEPWFHGPISRTTAEKLVVE----DGEFLVRESTACAGQFVLT--- 357
C P A + E W+ G I R AE+ ++ G FL+RES G + L+
Sbjct: 127 CIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRD 186
Query: 358 -GARRGLH-KHLLL--VDPIGVVRTKDRVFDSVPHLIKYH 393
RG H KH + +D G T F+SV L++++
Sbjct: 187 WDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHY 226
>AK223629-1|BAD97349.1| 595|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 isoform 1 variant
protein.
Length = 595
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>AF178946-1|AAD53317.1| 624|Homo sapiens 70 kDa SHP-1L protein
protein.
Length = 624
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
>AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein.
Length = 380
Score = 35.9 bits (79), Expect = 0.27
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHK 365
T + + A W++G ++R AE + E +G+FL+R+S + F ++ G +K
Sbjct: 272 TGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNK 331
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
H + V R F ++ L++++ + PI +++
Sbjct: 332 HFKVQLVDNVYCIGQRRFHTMDELVEHY--KKAPIFTSE 368
>AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein.
Length = 304
Score = 35.9 bits (79), Expect = 0.27
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 309 TAEAQAALLAKEPWFHGPISRTTAEKLVVE---DGEFLVRESTACAGQFVLTGARRGLHK 365
T + + A W++G ++R AE + E +G+FL+R+S + F ++ G +K
Sbjct: 196 TGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNK 255
Query: 366 HLLLVDPIGVVRTKDRVFDSVPHLIKYHCSNELPIVSAD 404
H + V R F ++ L++++ + PI +++
Sbjct: 256 HFKVQLVDNVYCIGQRRFHTMDELVEHY--KKAPIFTSE 292
>AB079851-2|BAC81775.1| 595|Homo sapiens protein tyrosine
phosphatase SHP-1 protein.
Length = 595
Score = 35.9 bits (79), Expect = 0.27
Identities = 20/41 (48%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 320 EPWFHGPISRTTAEKLVVEDGE---FLVRESTACAGQFVLT 357
E W+HG +S AE L+ GE FLVRES + G FVL+
Sbjct: 108 ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLS 148
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.133 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 50,922,292
Number of Sequences: 224733
Number of extensions: 1799866
Number of successful extensions: 3556
Number of sequences better than 10.0: 364
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 286
Number of HSP's that attempted gapping in prelim test: 3160
Number of HSP's gapped (non-prelim): 420
length of query: 418
length of database: 73,234,838
effective HSP length: 92
effective length of query: 326
effective length of database: 52,559,402
effective search space: 17134365052
effective search space used: 17134365052
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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