Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002674-TA|BGIBMGA002674-PA|IPR001670|Iron-containing
alcohol dehydrogenase
(271 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8IWW8 Cluster: Alcohol dehydrogenase iron-containing 1... 351 1e-95
UniRef50_Q9U2M4 Cluster: Putative uncharacterized protein; n=2; ... 288 9e-77
UniRef50_Q6P2B6 Cluster: ADHFE1 protein; n=5; Fungi/Metazoa grou... 283 3e-75
UniRef50_Q5KPR1 Cluster: Alcohol dehydrogenase, putative; n=3; B... 265 9e-70
UniRef50_Q54GJ7 Cluster: Putative uncharacterized protein; n=1; ... 260 2e-68
UniRef50_A4T492 Cluster: Iron-containing alcohol dehydrogenase; ... 235 9e-61
UniRef50_A1SEL4 Cluster: Iron-containing alcohol dehydrogenase; ... 231 2e-59
UniRef50_Q978V8 Cluster: Alcohol dehydrogenase [ADH]; n=1; Therm... 227 2e-58
UniRef50_Q94532 Cluster: Putative type III alcohol dehydrogenase... 194 2e-48
UniRef50_Q49A19 Cluster: ADHFE1 protein; n=13; Coelomata|Rep: AD... 192 6e-48
UniRef50_UPI00015BAE59 Cluster: Alcohol dehydrogenase; n=1; Igni... 175 7e-43
UniRef50_A7D7U5 Cluster: Iron-containing alcohol dehydrogenase; ... 146 5e-34
UniRef50_A3ZRV1 Cluster: Iron-containing alcohol dehydrogenase; ... 117 4e-25
UniRef50_Q6HZA9 Cluster: Alcohol dehydrogenase, iron-containing;... 116 5e-25
UniRef50_Q5KYJ9 Cluster: Alcohol dehydrogenase; n=7; Bacillaceae... 111 1e-23
UniRef50_A5MZX1 Cluster: DhaT1; n=1; Clostridium kluyveri DSM 55... 111 2e-23
UniRef50_Q127Q6 Cluster: Iron-containing alcohol dehydrogenase; ... 111 2e-23
UniRef50_Q1NLZ5 Cluster: Iron-containing alcohol dehydrogenase; ... 108 1e-22
UniRef50_Q11EZ5 Cluster: Iron-containing alcohol dehydrogenase; ... 108 2e-22
UniRef50_A1R2J5 Cluster: NAD(P)-dependent methanol dehydrogenase... 105 9e-22
UniRef50_O67218 Cluster: 1,3 propanediol dehydrogenase; n=1; Aqu... 105 2e-21
UniRef50_Q898F2 Cluster: 1,3-propanediol dehydrogenase; n=6; Clo... 102 1e-20
UniRef50_A6BZI7 Cluster: Putative iron alcohol dehydrogenase; n=... 100 3e-20
UniRef50_A3DCF3 Cluster: Iron-containing alcohol dehydrogenase; ... 99 6e-20
UniRef50_Q3Y3Q2 Cluster: Iron-containing alcohol dehydrogenase; ... 99 1e-19
UniRef50_A5UU06 Cluster: Iron-containing alcohol dehydrogenase; ... 99 1e-19
UniRef50_Q6LZ27 Cluster: Iron-containing alcohol dehydrogenase; ... 99 1e-19
UniRef50_Q5QL37 Cluster: Alcohol dehydrogenase; n=1; Geobacillus... 98 2e-19
UniRef50_Q5KYT0 Cluster: Alcohol dehydrogenase; n=3; Bacillaceae... 98 2e-19
UniRef50_Q8DM94 Cluster: CoA-linked acetaldehyde dehydrogenase a... 98 2e-19
UniRef50_Q6AQV2 Cluster: Related to 1,3-propanediol dehydrogenas... 98 2e-19
UniRef50_Q1QCB5 Cluster: Iron-containing alcohol dehydrogenase; ... 97 4e-19
UniRef50_Q67MQ9 Cluster: Iron-containing alcohol dehydrogenase; ... 96 7e-19
UniRef50_A6VXN3 Cluster: Iron-containing alcohol dehydrogenase; ... 96 1e-18
UniRef50_A4L2U7 Cluster: Alcohol/acetaldehyde dehydrogenase; n=1... 95 1e-18
UniRef50_A5KMH6 Cluster: Putative uncharacterized protein; n=1; ... 94 4e-18
UniRef50_UPI0000498B44 Cluster: alcohol dehydrogenase; n=1; Enta... 93 5e-18
UniRef50_Q98B58 Cluster: Alcohol dehydrogenase; n=8; Alphaproteo... 93 7e-18
UniRef50_A6NTK3 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_A3UHY4 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_A1I9B7 Cluster: Iron-containing alcohol dehydrogenase; ... 92 2e-17
UniRef50_UPI000038E2A2 Cluster: hypothetical protein Faci_030001... 91 2e-17
UniRef50_Q1FNN5 Cluster: Iron-containing alcohol dehydrogenase; ... 91 2e-17
UniRef50_Q9WWD4 Cluster: AttL; n=42; Proteobacteria|Rep: AttL - ... 91 3e-17
UniRef50_Q578L7 Cluster: Alcohol dehydrogenase, iron-containing;... 91 4e-17
UniRef50_Q30W85 Cluster: Alcetaldehyde dehydrogenase or NADPH-de... 90 5e-17
UniRef50_A5MYY1 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_A5YT21 Cluster: Alcohol dehydrogenase; n=1; uncultured ... 90 6e-17
UniRef50_A6W0M4 Cluster: Iron-containing alcohol dehydrogenase; ... 89 8e-17
UniRef50_Q9YAH6 Cluster: Alcohol dehydrogenase; n=1; Aeropyrum p... 89 1e-16
UniRef50_P71017 Cluster: Alcohol dehydrogenase; n=9; Bacillus|Re... 89 1e-16
UniRef50_Q87IP0 Cluster: Alcohol dehydrogenase; n=17; cellular o... 89 1e-16
UniRef50_A5D4Z8 Cluster: Alcohol dehydrogenase; n=1; Pelotomacul... 89 1e-16
UniRef50_UPI00015BD369 Cluster: UPI00015BD369 related cluster; n... 88 2e-16
UniRef50_O68647 Cluster: Alcohol dehydrogenase; n=7; Bacteria|Re... 88 2e-16
UniRef50_O73950 Cluster: Iron containing alcohol dehydrogenase; ... 88 3e-16
UniRef50_Q2SC87 Cluster: Alcohol dehydrogenase, class IV; n=8; G... 87 3e-16
UniRef50_Q18XS4 Cluster: Iron-containing alcohol dehydrogenase; ... 87 4e-16
UniRef50_A1VAN7 Cluster: Iron-containing alcohol dehydrogenase; ... 87 6e-16
UniRef50_P10127 Cluster: Alcohol dehydrogenase 4; n=4; Ascomycot... 87 6e-16
UniRef50_Q8GAW4 Cluster: 5-hydroxyvalerate dehydrogenase; n=2; P... 86 1e-15
UniRef50_A3XYH0 Cluster: Alcohol dehydrogenase, iron-containing;... 86 1e-15
UniRef50_Q4KCL4 Cluster: Alcohol dehydrogenase, iron-containing;... 85 1e-15
UniRef50_Q93CV7 Cluster: Putative methanol dehydrogenase; n=2; L... 85 1e-15
UniRef50_O28260 Cluster: Alcohol dehydrogenase, iron-containing;... 85 1e-15
UniRef50_Q98H17 Cluster: Dehydrogenase; iron-containing alcohol ... 85 2e-15
UniRef50_Q67M75 Cluster: Iron-containing alcohol dehydrogenase; ... 85 2e-15
UniRef50_Q3ZWC0 Cluster: Alcohol dehydrogenase, iron-containing;... 85 2e-15
UniRef50_A6VQQ6 Cluster: Iron-containing alcohol dehydrogenase; ... 85 2e-15
UniRef50_Q24803 Cluster: Aldehyde-alcohol dehydrogenase 2 [Inclu... 85 2e-15
UniRef50_A5UV11 Cluster: Iron-containing alcohol dehydrogenase; ... 84 3e-15
UniRef50_Q39NZ6 Cluster: Iron-containing alcohol dehydrogenase; ... 84 4e-15
UniRef50_Q0EUX2 Cluster: Iron-containing alcohol dehydrogenase; ... 84 4e-15
UniRef50_Q1GWE1 Cluster: Iron-containing alcohol dehydrogenase; ... 83 6e-15
UniRef50_A0UW83 Cluster: Iron-containing alcohol dehydrogenase; ... 83 6e-15
UniRef50_Q6D0N6 Cluster: Putative alcohol dehydrogenase; n=6; En... 83 7e-15
UniRef50_Q9APW5 Cluster: 1,3-propanediol dehydrogenase; n=4; Pse... 83 7e-15
UniRef50_A6M1I4 Cluster: Iron-containing alcohol dehydrogenase; ... 83 1e-14
UniRef50_Q8G420 Cluster: Adh2; n=60; cellular organisms|Rep: Adh... 82 1e-14
UniRef50_Q7UK80 Cluster: Putative iron alcohol dehydrogenase; n=... 82 1e-14
UniRef50_A5NN36 Cluster: Iron-containing alcohol dehydrogenase; ... 82 1e-14
UniRef50_Q1M843 Cluster: Putative alcohol dehydrogenase; n=1; Rh... 82 2e-14
UniRef50_A6X351 Cluster: Iron-containing alcohol dehydrogenase; ... 81 2e-14
UniRef50_A1RYX6 Cluster: Iron-containing alcohol dehydrogenase; ... 81 2e-14
UniRef50_Q184U3 Cluster: Alcohol dehydrogenase; n=2; Clostridium... 81 3e-14
UniRef50_A6FDL7 Cluster: Possible iron-containing alcohol dehydr... 81 4e-14
UniRef50_A1RUX3 Cluster: Iron-containing alcohol dehydrogenase; ... 81 4e-14
UniRef50_Q8G3T1 Cluster: Possible lactaldehyde reductase; n=8; B... 80 5e-14
UniRef50_Q97BQ7 Cluster: NADH dependent alcohol dehydrogenase; n... 80 5e-14
UniRef50_Q2BFJ3 Cluster: Putative alcohol dehydrogenase; n=1; Ba... 80 7e-14
UniRef50_Q1D0Q5 Cluster: Alcohol dehydrogenase, iron-containing;... 80 7e-14
UniRef50_A5D524 Cluster: Alcohol dehydrogenase; n=1; Pelotomacul... 80 7e-14
UniRef50_Q1D8D1 Cluster: Alcohol dehydrogenase, iron-containing;... 79 9e-14
UniRef50_A4E817 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14
UniRef50_P41795 Cluster: Ethanolamine utilization protein eutG; ... 79 9e-14
UniRef50_Q5PKG6 Cluster: Alcohol dehydrogenase; n=22; Gammaprote... 79 1e-13
UniRef50_Q3ABB6 Cluster: NADPH-dependent butanol dehydrogenase; ... 79 1e-13
UniRef50_Q0S803 Cluster: Possible Fe-containing alcohol dehydrog... 79 1e-13
UniRef50_A5D528 Cluster: Alcohol dehydrogenase; n=1; Pelotomacul... 79 2e-13
UniRef50_Q892C3 Cluster: Alcetaldehyde dehydrogenase or NADPH-de... 78 2e-13
UniRef50_A3DKJ8 Cluster: Iron-containing alcohol dehydrogenase; ... 78 2e-13
UniRef50_Q4FSW3 Cluster: Possible iron-containing alcohol dehydr... 78 3e-13
UniRef50_Q21X13 Cluster: Iron-containing alcohol dehydrogenase; ... 77 4e-13
UniRef50_Q9UZ43 Cluster: Alcohol dehydrogenase; n=4; Thermococca... 77 4e-13
UniRef50_Q97TN9 Cluster: Alcohol dehydrogenase; n=2; Bacteria|Re... 77 5e-13
UniRef50_A5GK32 Cluster: Alcohol dehydrogenase, class IV; n=2; S... 77 5e-13
UniRef50_Q89NF2 Cluster: Iron alcohol dehydrogenase; n=11; Alpha... 77 6e-13
UniRef50_Q165D6 Cluster: Alcohol dehydrogenase, iron-containing;... 77 6e-13
UniRef50_Q2FPG9 Cluster: Iron-containing alcohol dehydrogenase; ... 77 6e-13
UniRef50_O30211 Cluster: Alcohol dehydrogenase, iron-containing;... 77 6e-13
UniRef50_Q65WI4 Cluster: EutG protein; n=1; Mannheimia succinici... 76 8e-13
UniRef50_Q2RVZ0 Cluster: Iron-containing alcohol dehydrogenase; ... 76 8e-13
UniRef50_Q1GCV3 Cluster: Iron-containing alcohol dehydrogenase; ... 76 8e-13
UniRef50_Q0LWU7 Cluster: Iron-containing alcohol dehydrogenase; ... 76 8e-13
UniRef50_A5TRI3 Cluster: Alcohol dehydrogenase; n=1; Fusobacteri... 76 8e-13
UniRef50_A3J834 Cluster: Iron-containing alcohol dehydrogenase; ... 76 8e-13
UniRef50_P13604 Cluster: NADPH-dependent butanol dehydrogenase; ... 76 8e-13
UniRef50_P38945 Cluster: NAD-dependent 4-hydroxybutyrate dehydro... 76 8e-13
UniRef50_A3PTT4 Cluster: Iron-containing alcohol dehydrogenase; ... 76 1e-12
UniRef50_A3HBD1 Cluster: Iron-containing alcohol dehydrogenase; ... 76 1e-12
UniRef50_A2U751 Cluster: Iron-containing alcohol dehydrogenase; ... 76 1e-12
UniRef50_UPI000051A9D0 Cluster: PREDICTED: similar to alcohol de... 75 1e-12
UniRef50_Q4Q784 Cluster: Alcohol dehydrogenase, putative; n=3; L... 75 1e-12
UniRef50_Q1IUR6 Cluster: Iron-containing alcohol dehydrogenase; ... 75 2e-12
UniRef50_A3DIK0 Cluster: Iron-containing alcohol dehydrogenase; ... 75 2e-12
UniRef50_Q2G4J2 Cluster: Iron-containing alcohol dehydrogenase; ... 75 3e-12
UniRef50_A1U008 Cluster: Iron-containing alcohol dehydrogenase; ... 75 3e-12
UniRef50_O86272 Cluster: Alcohol-acetaldehyde dehydrogenase; n=1... 74 3e-12
UniRef50_A6BEI0 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12
UniRef50_A4BN71 Cluster: Alcohol dehydrogenase, class IV; n=6; P... 74 3e-12
UniRef50_O29908 Cluster: Alcohol dehydrogenase, iron-containing;... 74 3e-12
UniRef50_Q18QL8 Cluster: Iron-containing alcohol dehydrogenase; ... 74 4e-12
UniRef50_A5ZA28 Cluster: Putative uncharacterized protein; n=1; ... 74 4e-12
UniRef50_A6TJU4 Cluster: Iron-containing alcohol dehydrogenase; ... 73 6e-12
UniRef50_A6D0S9 Cluster: Alcohol dehydrogenase; n=1; Vibrio shil... 73 6e-12
UniRef50_A1HIY6 Cluster: Iron-containing alcohol dehydrogenase; ... 73 6e-12
UniRef50_Q9X022 Cluster: Alcohol dehydrogenase, iron-containing;... 73 8e-12
UniRef50_Q9KFE7 Cluster: NAD-dependent methanol dehydrogenase; n... 73 8e-12
UniRef50_Q88TC1 Cluster: 1,3-propanediol dehydrogenase; n=8; Lac... 73 8e-12
UniRef50_Q8XLZ8 Cluster: NADPH-dependent butanol dehydrogenase; ... 73 1e-11
UniRef50_Q2F7L2 Cluster: Alcohol dehydrogenase class IV; n=5; La... 73 1e-11
UniRef50_P0A9S2 Cluster: Lactaldehyde reductase; n=45; Bacteria|... 73 1e-11
UniRef50_Q59104 Cluster: NAD-dependent 4-hydroxybutyrate dehydro... 72 1e-11
UniRef50_A3HQR7 Cluster: Iron-containing alcohol dehydrogenase; ... 72 1e-11
UniRef50_Q8Y7U8 Cluster: PduQ protein; n=20; Firmicutes|Rep: Pdu... 72 2e-11
UniRef50_Q3A7X4 Cluster: Alcohol dehydrogenase, class IV; n=1; P... 71 2e-11
UniRef50_A0PUM1 Cluster: Aldehyde dehydrogenase; n=2; Mycobacter... 71 2e-11
UniRef50_Q8RBW2 Cluster: Alcohol dehydrogenase IV; n=12; cellula... 71 4e-11
UniRef50_Q0S3P9 Cluster: 1,3-propanediol dehydrogenase; n=5; Act... 71 4e-11
UniRef50_Q1NU70 Cluster: Iron-containing alcohol dehydrogenase; ... 70 6e-11
UniRef50_A0W873 Cluster: Iron-containing alcohol dehydrogenase; ... 70 6e-11
UniRef50_Q9WZS7 Cluster: NADH-dependent butanol dehydrogenase, p... 70 7e-11
UniRef50_A1AJ15 Cluster: Putative iron-containing alcohol dehydr... 70 7e-11
UniRef50_Q6Q906 Cluster: Predicted NAD-dependent 4-hydroxybutyra... 70 7e-11
UniRef50_A6M0N3 Cluster: Iron-containing alcohol dehydrogenase; ... 70 7e-11
UniRef50_A1HNQ8 Cluster: Iron-containing alcohol dehydrogenase; ... 70 7e-11
UniRef50_A3I686 Cluster: 1,3-propanediol dehydrogenase; n=1; Bac... 69 1e-10
UniRef50_Q1EZ60 Cluster: Alcohol dehydrogenase; n=3; Clostridial... 69 1e-10
UniRef50_A3Y9V5 Cluster: Iron-containing alcohol dehydrogenase; ... 69 1e-10
UniRef50_Q0C5T5 Cluster: 4-hydroxybutyrate dehydrogenase, NAD-de... 68 2e-10
UniRef50_A5KMY5 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_A4AC61 Cluster: Alcohol dehydrogenase, iron-containing;... 68 2e-10
UniRef50_A6LP70 Cluster: Iron-containing alcohol dehydrogenase; ... 68 3e-10
UniRef50_A5ZM66 Cluster: Putative uncharacterized protein; n=2; ... 68 3e-10
UniRef50_A5N1L2 Cluster: Predicted iron containing alcohol dehyd... 68 3e-10
UniRef50_Q8KDU3 Cluster: Alcohol dehydrogenase, iron-containing;... 67 4e-10
UniRef50_Q7R169 Cluster: GLP_447_53872_52544; n=2; Giardia intes... 67 5e-10
UniRef50_Q5L3J5 Cluster: Alcohol dehydrogenase; n=1; Geobacillus... 66 7e-10
UniRef50_A6PLH8 Cluster: Iron-containing alcohol dehydrogenase; ... 66 9e-10
UniRef50_A7TAX8 Cluster: Predicted protein; n=1; Nematostella ve... 66 9e-10
UniRef50_Q31J66 Cluster: Iron-containing alcohol dehydrogenase; ... 66 1e-09
UniRef50_Q1JXM5 Cluster: Iron-containing alcohol dehydrogenase; ... 66 1e-09
UniRef50_A3HAZ3 Cluster: Iron-containing alcohol dehydrogenase; ... 66 1e-09
UniRef50_A6GSB4 Cluster: Iron-containing alcohol dehydrogenase; ... 65 2e-09
UniRef50_A4RY11 Cluster: Predicted protein; n=2; Ostreococcus|Re... 65 2e-09
UniRef50_Q894T1 Cluster: Alcohol dehydrogenase 2; n=5; Clostridi... 64 4e-09
UniRef50_Q97N98 Cluster: Alcohol dehydrogenase, iron-containing;... 64 5e-09
UniRef50_A6PCI9 Cluster: Iron-containing alcohol dehydrogenase; ... 63 6e-09
UniRef50_Q30VG9 Cluster: Alcohol dehydrogenase, iron-containing;... 62 1e-08
UniRef50_A4C4S1 Cluster: Alcohol dehydrogenase; n=1; Pseudoalter... 62 1e-08
UniRef50_A4J4M6 Cluster: Iron-containing alcohol dehydrogenase; ... 62 1e-08
UniRef50_A1WPM6 Cluster: Iron-containing alcohol dehydrogenase; ... 62 1e-08
UniRef50_A0KHX0 Cluster: Alcohol dehydrogenase, iron-containing;... 62 1e-08
UniRef50_A4XJK8 Cluster: Iron-containing alcohol dehydrogenase; ... 62 2e-08
UniRef50_A1B5B0 Cluster: Iron-containing alcohol dehydrogenase; ... 62 2e-08
UniRef50_Q53062 Cluster: NDMA-dependent methanol dehydrogenase; ... 62 2e-08
UniRef50_Q839H5 Cluster: NADH-dependent butanol dehydrogenase, p... 61 3e-08
UniRef50_A7HJ36 Cluster: Iron-containing alcohol dehydrogenase; ... 61 3e-08
UniRef50_A5G7F4 Cluster: Iron-containing alcohol dehydrogenase; ... 61 3e-08
UniRef50_Q2RJQ1 Cluster: Iron-containing alcohol dehydrogenase; ... 61 3e-08
UniRef50_A0WAX9 Cluster: Iron-containing alcohol dehydrogenase; ... 61 3e-08
UniRef50_Q9XDN0 Cluster: Propanediol utilization propanol dehydr... 60 4e-08
UniRef50_Q28JU8 Cluster: Iron-containing alcohol dehydrogenase; ... 60 4e-08
UniRef50_A6LNP6 Cluster: Iron-containing alcohol dehydrogenase; ... 60 4e-08
UniRef50_P33744 Cluster: Aldehyde-alcohol dehydrogenase [Include... 60 4e-08
UniRef50_Q82WP4 Cluster: Iron-containing alcohol dehydrogenase; ... 60 8e-08
UniRef50_A4J7X7 Cluster: Iron-containing alcohol dehydrogenase; ... 60 8e-08
UniRef50_Q59477 Cluster: 1,3-propanediol dehydrogenase; n=152; c... 60 8e-08
UniRef50_A6CD83 Cluster: Iron-containing alcohol dehydrogenase; ... 59 1e-07
UniRef50_Q3LFI0 Cluster: NADPH-dependent butanol dehydrogenase; ... 59 1e-07
UniRef50_Q1JYE4 Cluster: Iron-containing alcohol dehydrogenase; ... 59 1e-07
UniRef50_A6P0M2 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_A6PUH9 Cluster: Iron-containing alcohol dehydrogenase; ... 58 2e-07
UniRef50_A6BJ73 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_A5G7G0 Cluster: Iron-containing alcohol dehydrogenase; ... 58 2e-07
UniRef50_Q8EVE3 Cluster: NADH-dependent butanol dehydrogenase; n... 57 4e-07
UniRef50_Q87QB5 Cluster: Iron-containing alcohol dehydrogenase; ... 57 4e-07
UniRef50_Q11AP6 Cluster: Iron-containing alcohol dehydrogenase; ... 57 6e-07
UniRef50_A1K911 Cluster: Conserved hypothetical alcohol dehydrog... 57 6e-07
UniRef50_Q0I6R5 Cluster: Iron-containing alcohol dehydrogenase; ... 56 1e-06
UniRef50_A3UPZ4 Cluster: Alcohol dehydrogenase; n=2; Vibrio|Rep:... 56 1e-06
UniRef50_Q392F4 Cluster: Iron-containing alcohol dehydrogenase; ... 56 1e-06
UniRef50_Q97IR6 Cluster: NAD-dependent 4-hydroxybutyrate dehydro... 55 2e-06
UniRef50_Q0RL39 Cluster: Putative alcohol dehydrogenase with deh... 54 3e-06
UniRef50_A0IVC7 Cluster: Iron-containing alcohol dehydrogenase; ... 54 4e-06
UniRef50_UPI000039369F Cluster: COG1979: Uncharacterized oxidore... 54 5e-06
UniRef50_Q122F9 Cluster: Iron-containing alcohol dehydrogenase; ... 54 5e-06
UniRef50_Q1NUM2 Cluster: Iron-containing alcohol dehydrogenase; ... 53 9e-06
UniRef50_A6PN65 Cluster: Iron-containing alcohol dehydrogenase; ... 52 1e-05
UniRef50_Q8D7E3 Cluster: Uncharacterized oxidoreductase; n=6; Pr... 52 2e-05
UniRef50_A6VNF5 Cluster: Iron-containing alcohol dehydrogenase; ... 52 2e-05
UniRef50_Q93N32 Cluster: NADH-dependent butanol dehydrogenase Bd... 51 3e-05
UniRef50_A7B601 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A6FNK8 Cluster: Ornithine cyclodeaminase; n=3; Rhodobac... 51 3e-05
UniRef50_A1WTC2 Cluster: Iron-containing alcohol dehydrogenase; ... 51 3e-05
UniRef50_Q8AAD0 Cluster: Iron-containing alcohol dehydrogenase; ... 50 5e-05
UniRef50_A6NPH8 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q8KDA2 Cluster: Alcohol dehydrogenase, iron-containing;... 50 8e-05
UniRef50_Q7M9F4 Cluster: BUTANOL DEHYDROGENASE; n=1; Wolinella s... 50 8e-05
UniRef50_A1VAL7 Cluster: Iron-containing alcohol dehydrogenase; ... 50 8e-05
UniRef50_Q9XBE8 Cluster: Putative alcohol dehydrogenase; n=1; Am... 49 1e-04
UniRef50_A5ELU4 Cluster: Putative alcohol dehydrogenase; n=1; Br... 49 1e-04
UniRef50_Q8XM32 Cluster: NADH-dependent butanol dehydrogenase; n... 49 1e-04
UniRef50_Q8R6C2 Cluster: NADPH-dependent butanol dehydrogenase; ... 49 1e-04
UniRef50_Q73LF0 Cluster: Alcohol dehydrogenase, iron-containing;... 49 1e-04
UniRef50_Q2G5I2 Cluster: Iron-containing alcohol dehydrogenase; ... 49 1e-04
UniRef50_Q46856 Cluster: Alcohol dehydrogenase yqhD; n=123; cell... 49 1e-04
UniRef50_Q9KVA0 Cluster: Iron-containing alcohol dehydrogenase f... 48 2e-04
UniRef50_Q8Y7V3 Cluster: Lmo1166 protein; n=12; Listeria|Rep: Lm... 48 3e-04
UniRef50_Q64T53 Cluster: Putative alcohol dehydrogenase; n=1; Ba... 48 3e-04
UniRef50_Q9KLP1 Cluster: Iron-containing alcohol dehydrogenase; ... 48 3e-04
UniRef50_Q4P7J9 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q89VQ0 Cluster: Maleylacetate reductase; n=5; Bradyrhiz... 47 6e-04
UniRef50_Q30WM6 Cluster: Alcohol dehydrogenase, iron-containing;... 47 6e-04
UniRef50_A0VE95 Cluster: Iron-containing alcohol dehydrogenase; ... 47 6e-04
UniRef50_Q9Z659 Cluster: NADH-dependent butanol dehydrogenase; n... 45 0.002
UniRef50_A6A276 Cluster: NADH-dependent butanol dehydrogenase a;... 45 0.002
UniRef50_UPI0000499FE8 Cluster: alcohol dehydrogenase, iron-cont... 45 0.002
UniRef50_A6AXJ9 Cluster: NADH-dependent butanol dehydrogenase a;... 45 0.002
UniRef50_Q5V2L6 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 45 0.002
UniRef50_O05240 Cluster: Probable NADH-dependent butanol dehydro... 45 0.002
UniRef50_Q24857 Cluster: Alcohol dehydrogenase 3; n=12; Entamoeb... 44 0.003
UniRef50_Q04945 Cluster: NADH-dependent butanol dehydrogenase B;... 44 0.004
UniRef50_Q0RC27 Cluster: Putative alcohol dehydrogenase; n=1; Fr... 44 0.005
UniRef50_A1B6Z7 Cluster: Iron-containing alcohol dehydrogenase; ... 43 0.010
UniRef50_Q9HJY0 Cluster: NADPH-dependent butanol dehydrogenase r... 42 0.017
UniRef50_P94135 Cluster: Maleylacetate reductase 2; n=9; Proteob... 42 0.017
UniRef50_Q9F8G9 Cluster: NADH-dependent butanol dehydrogenase; n... 41 0.039
UniRef50_Q2LQJ7 Cluster: Alcohol dehydrogenase, class IV; n=1; S... 40 0.051
UniRef50_P74880 Cluster: Alcohol dehydrogenase; n=15; Gammaprote... 40 0.051
UniRef50_Q5FP52 Cluster: NADH-dependent iron-containing alcohol ... 40 0.068
UniRef50_Q5CW43 Cluster: NAD dependent dehydrogenase of possible... 40 0.089
UniRef50_Q052S6 Cluster: Alcohol dehyodrogenase; n=4; Bacteria|R... 39 0.12
UniRef50_A0RMJ4 Cluster: Iron-containing alcohol dehydrogenase; ... 39 0.12
UniRef50_A2FLJ0 Cluster: Alcohol dehydrogenase, iron-containing ... 39 0.12
UniRef50_Q8R612 Cluster: NADH-dependent butanol dehydrogenase A;... 39 0.16
UniRef50_Q7MVC2 Cluster: Alcohol dehydrogenase, iron-containing;... 38 0.21
UniRef50_P96075 Cluster: FomC protein; n=1; Streptomyces wedmore... 38 0.36
UniRef50_A2RB83 Cluster: Similarity to alcohol-acetaldehyde dehy... 36 1.1
UniRef50_UPI00004987AB Cluster: alcohol dehydrogenase; n=1; Enta... 36 1.5
UniRef50_Q0K1B8 Cluster: Alcohol dehydrogenase, class IV; n=2; C... 36 1.5
UniRef50_Q1AX61 Cluster: Iron-containing alcohol dehydrogenase; ... 35 1.9
UniRef50_Q5IW41 Cluster: Putative PhpC; n=1; Streptomyces virido... 35 2.5
UniRef50_A2EBD4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.9
UniRef50_Q0CUU3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.9
UniRef50_Q972U6 Cluster: Putative uncharacterized protein ST1038... 33 5.9
UniRef50_UPI00006CBA2F Cluster: hypothetical protein TTHERM_0055... 33 7.7
UniRef50_UPI00005F6371 Cluster: hypothetical protein MtubC_01002... 33 7.7
UniRef50_A6M0K3 Cluster: Cell wall hydrolase/autolysin precursor... 33 7.7
UniRef50_A1RAC3 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
>UniRef50_Q8IWW8 Cluster: Alcohol dehydrogenase iron-containing 1;
n=45; Fungi/Metazoa group|Rep: Alcohol dehydrogenase
iron-containing 1 - Homo sapiens (Human)
Length = 467
Score = 351 bits (863), Expect = 1e-95
Identities = 154/270 (57%), Positives = 199/270 (73%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
MTD N++ L P++ +DSL +NGI + VYD VRVEPTD SF +AI FA++G FD++VA+G
Sbjct: 79 MTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVG 138
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDTCKAANLY S P ++FLDYV+AP+GKGK V++ +KP+IA+P
Sbjct: 139 GGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVA 198
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
IFDYE + K GI+ A++P L LIDPLHTL +P +V SGFD+ CHALES+T +P+
Sbjct: 199 IFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHL 258
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
R P P+NP RPAYQGSNPISD+WA L+ + KY R+V N D+EARS MHLA+ AG
Sbjct: 259 RSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRNPDDLEARSHMHLASAFAG 318
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKSFVPEDY 270
+G GNAGVHLCHG++YPI+G VK + +DY
Sbjct: 319 IGFGNAGVHLCHGMSYPISGLVKMYKAKDY 348
>UniRef50_Q9U2M4 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 465
Score = 288 bits (707), Expect = 9e-77
Identities = 134/270 (49%), Positives = 177/270 (65%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD NV + K +L I Y+V+D V +EPT S + AI FAK FDSF+A+G
Sbjct: 76 ITDKNVQNTIAFKNAEQALKMVNIEYEVFDDVLIEPTVNSMQKAIAFAKSKQFDSFIAVG 135
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+DT KAA LY S+P+A+FLD+V P GK + P+IA+P
Sbjct: 136 GGSVIDTTKAAALYASNPEADFLDFVGPPFGKSMQPKNPMLPLIAVPTTAGTGSETTAAA 195
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I D E KTGI ++P LA++DPL+ +++P V+ YSGFD+ CHALESFTA+PF +
Sbjct: 196 IMDLPEHKCKTGIRLRCIKPYLAVVDPLNVMSMPRNVAIYSGFDVLCHALESFTALPFDQ 255
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
R P P NP +RP YQGSNPISDVW++ L+ + KYF RS+ + D EAR+ M A++ AG
Sbjct: 256 RSPRPENPGVRPLYQGSNPISDVWSKEALRIIGKYFRRSIFDPTDEEARTEMLKASSFAG 315
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKSFVPEDY 270
+G GNAGVHLCHGL+YPI+ KS V +DY
Sbjct: 316 IGFGNAGVHLCHGLSYPISSQAKSCVADDY 345
>UniRef50_Q6P2B6 Cluster: ADHFE1 protein; n=5; Fungi/Metazoa
group|Rep: ADHFE1 protein - Homo sapiens (Human)
Length = 255
Score = 283 bits (694), Expect = 3e-75
Identities = 124/223 (55%), Positives = 163/223 (73%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
MTD N++ L P++ +DSL +NGI + VYD VRVEPTD SF +AI FA++G FD++VA+G
Sbjct: 31 MTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDTCKAANLY S P ++FLDYV+AP+GKGK V++ +KP+IA+P
Sbjct: 91 GGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVA 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
IFDYE + K GI+ A++P L LIDPLHTL +P +V SGFD+ CHALES+T +P+
Sbjct: 151 IFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSGFDVLCHALESYTTLPYHL 210
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNS 223
R P P+NP RPAYQGSNPISD+WA L+ + KY R+VN++
Sbjct: 211 RSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVNST 253
>UniRef50_Q5KPR1 Cluster: Alcohol dehydrogenase, putative; n=3;
Basidiomycota|Rep: Alcohol dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 519
Score = 265 bits (649), Expect = 9e-70
Identities = 122/259 (47%), Positives = 176/259 (67%), Gaps = 1/259 (0%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
TDPNVA L ++ V +SL R G+N+ ++DK VEPTD S+++AI F++ + F+A+GG
Sbjct: 115 TDPNVAKLPVIEIVEESLLRAGLNFVMWDKCAVEPTDKSWQEAIDFSRSSHLTHFLAVGG 174
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GS MDT KAANL+ + P A+ +++NAP+GKG + ++ P+IAIP I
Sbjct: 175 GSSMDTAKAANLFTNYPKADLFEFINAPIGKGTPITKKLSPLIAIPTTAGTGSETTGTAI 234
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
D KTGI+ AL+P L ++D L+T T P++V+ +G D+ H+LES+TA+P+ +R
Sbjct: 235 LDIPSRKFKTGIASRALKPTLGIVDLLNTTTCPKEVAIAAGLDVLFHSLESWTAVPYHQR 294
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNS-GDVEARSSMHLAATMAG 240
P PANP RPAYQGSNPISD+++++ L+T KY R + GD EAR+ M LAA+ AG
Sbjct: 295 TPRPANPINRPAYQGSNPISDIFSKWALETTVKYLPRIARDPFGDEEARAQMLLAASTAG 354
Query: 241 VGIGNAGVHLCHGLAYPIA 259
+G GNAGVH+CH +YPI+
Sbjct: 355 IGFGNAGVHMCHAFSYPIS 373
>UniRef50_Q54GJ7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 547
Score = 260 bits (638), Expect = 2e-68
Identities = 136/267 (50%), Positives = 169/267 (63%), Gaps = 6/267 (2%)
Query: 10 SPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK 69
S + L SL + GI Y +Y V +EPTD SFKDAI +G +D VA+GGGSVMDT K
Sbjct: 161 SAVAKCLYSLEKCGIKYTIYSDVSIEPTDTSFKDAISVMGKGRYDGVVAVGGGSVMDTAK 220
Query: 70 AANLYYSDP--DAEFLDYVNAPVGKGKAVNIQVK-PMIAIPXXXXXXXXXXXXXIFDY-- 124
AANLY S P D +FL Y+N P+GKG V +K P+IAIP I D
Sbjct: 221 AANLYNSYPPADNDFLAYINPPIGKGLLVPGPLKRPLIAIPTTCGTASETTGVCILDIKL 280
Query: 125 -EEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGP 183
+ + AKTGI+ L+PIL L+DP + LT+P V+ SGFD CHALESFTAIPF +R P
Sbjct: 281 GDGLSAKTGIASRHLKPILGLVDPDNLLTLPSNVAISSGFDQLCHALESFTAIPFNQRSP 340
Query: 184 APANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGI 243
P P RP+YQG+NP+SDVW+ L+ L K R V N D ARS M LAA+ AG+G
Sbjct: 341 RPLAPNQRPSYQGANPVSDVWSLRSLEMLCKNIHRFVLNPNDDYARSQMMLAASYAGLGF 400
Query: 244 GNAGVHLCHGLAYPIAGNVKSFVPEDY 270
GN+GVH CHG++Y I+ VK + PE Y
Sbjct: 401 GNSGVHACHGMSYSISSMVKDYKPEGY 427
>UniRef50_A4T492 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Mycobacterium|Rep: Iron-containing alcohol
dehydrogenase - Mycobacterium gilvum PYR-GCK
Length = 435
Score = 235 bits (575), Expect = 9e-61
Identities = 129/269 (47%), Positives = 161/269 (59%), Gaps = 2/269 (0%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
+D VA L A SL GI+ Y VRVEPTD SF+ A FA E + D ++++GG
Sbjct: 50 SDSAVAQLEVFDAAQRSLRAAGIDVVDYIDVRVEPTDESFRSAAAFATEASPDGYISVGG 109
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GSV+DT KAANLY + P A+FL+YVNAPVG G V + P IA P I
Sbjct: 110 GSVIDTAKAANLYATHP-ADFLEYVNAPVGAGAPVPGPLAPHIACPTTSGTGSEVTGIAI 168
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
FD + AKTGI+ ALRP AL+DP T T+P V SG D+ HALES+TA P+T R
Sbjct: 169 FDLLSMAAKTGIASPALRPTEALVDPDCTGTLPATVVACSGLDVLSHALESYTARPYTHR 228
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
APA P RP QG+NP SD+ L+ L Y R+V ++ D EAR + AAT+AG+
Sbjct: 229 A-APARPTQRPMSQGANPWSDLGCGEALRLLGTYLARAVADASDSEAREQVMWAATLAGI 287
Query: 242 GIGNAGVHLCHGLAYPIAGNVKSFVPEDY 270
GNAGVHL H +AY +AG V+ F P Y
Sbjct: 288 AFGNAGVHLPHAMAYAVAGQVRDFRPVGY 316
>UniRef50_A1SEL4 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 418
Score = 231 bits (564), Expect = 2e-59
Identities = 119/271 (43%), Positives = 161/271 (59%), Gaps = 4/271 (1%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKE-GNFDSFVAI 59
+TDP VA+ + + +T GI YD+V VEPTD S +AI FA++ G FD+ +A+
Sbjct: 38 VTDPGVAATGHPERIAAQVTARGIEVTTYDRVHVEPTDESLAEAIDFARDAGPFDAILAV 97
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGS +DT KA NL ++P E +DYVNAPVG+ +A + P++AIP
Sbjct: 98 GGGSSIDTAKAVNLLTTNP-GELMDYVNAPVGRAQAPQHPLLPLVAIPTTTGTGAESTTI 156
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ D + KTGISH LRP LA++DP T++ P V+ +G DI CHALES+TA +
Sbjct: 157 CVLDVLALKVKTGISHPRLRPTLAVVDPALTISQPAVVTAAAGLDIVCHALESYTARWYA 216
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
E P R Y G+NPISD+W+ L L F +V + D AR M +AAT A
Sbjct: 217 EFD--AKQPEQRVPYCGANPISDLWSERALSLLAGSFRAAVRDGSDRAAREQMAMAATFA 274
Query: 240 GVGIGNAGVHLCHGLAYPIAGNVKSFVPEDY 270
G+G GNAGVH+ H AYPIAG V+ + P+ Y
Sbjct: 275 GLGFGNAGVHIPHANAYPIAGRVRDYRPDGY 305
>UniRef50_Q978V8 Cluster: Alcohol dehydrogenase [ADH]; n=1;
Thermoplasma volcanium|Rep: Alcohol dehydrogenase [ADH]
- Thermoplasma volcanium
Length = 433
Score = 227 bits (556), Expect = 2e-58
Identities = 111/267 (41%), Positives = 158/267 (59%), Gaps = 2/267 (0%)
Query: 4 PNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGS 63
P + VL SL+ +GINY V+D+V+ EP D + K D ++ GGGS
Sbjct: 51 PRLKDSKQFHDVLSSLSESGINYAVFDEVKTEPDDENLTKGYEAIKGKKIDGLISFGGGS 110
Query: 64 VMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFD 123
+DT K NL Y P + DY+N P+GKG + P IAIP IFD
Sbjct: 111 TIDTAKILNLLYKYP-RDINDYINKPIGKGMIPEGDLLPHIAIPTTAGTGSETTNVTIFD 169
Query: 124 YEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGP 183
E +H KTGIS+ +RP LA+IDP++TLT+P KV+ +G D+ HA+ES+T+ P+T R P
Sbjct: 170 VERLHVKTGISNPFIRPSLAIIDPVNTLTMPPKVTASTGLDVLNHAIESYTSHPYTARPP 229
Query: 184 APANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGI 243
A+P RP Y GS PI D++ ++ + KY R+ + D+EAR M + A++AG+G
Sbjct: 230 V-ASPDERPVYSGSTPIGDLFGLQAIEWVHKYLRRAFADPLDLEARYYMTMGASIAGMGF 288
Query: 244 GNAGVHLCHGLAYPIAGNVKSFVPEDY 270
G+ GVH+ H +AYPIAG +K + P+DY
Sbjct: 289 GHVGVHIPHAMAYPIAGMIKKWHPDDY 315
>UniRef50_Q94532 Cluster: Putative type III alcohol dehydrogenase;
n=1; Drosophila melanogaster|Rep: Putative type III
alcohol dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 397
Score = 194 bits (474), Expect = 2e-48
Identities = 81/127 (63%), Positives = 107/127 (84%)
Query: 144 LIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDV 203
+IDPLHTL+ P++V ++GFD+FCHALESFTA+ + ERG AP++P+LRP YQG NP+SDV
Sbjct: 152 VIDPLHTLSQPQRVMAFAGFDVFCHALESFTAVDYRERGLAPSDPSLRPTYQGRNPVSDV 211
Query: 204 WARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGNVK 263
WARF L+T++K FV ++ ++EARS MHLA+TMAGVG GNAGVHLCHGL+YPI+GNV+
Sbjct: 212 WARFALETIRKNFVNAIYQPDNLEARSQMHLASTMAGVGFGNAGVHLCHGLSYPISGNVR 271
Query: 264 SFVPEDY 270
+ P+ Y
Sbjct: 272 DYKPKGY 278
Score = 102 bits (245), Expect = 8e-21
Identities = 47/74 (63%), Positives = 56/74 (75%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD NV L +K LDSL RNGINY+VYD+ RVEPTDGS A+ FA+ FD+F+AIG
Sbjct: 76 VTDKNVVQLPSVKVALDSLARNGINYEVYDETRVEPTDGSMWHAVEFARGKEFDAFLAIG 135
Query: 61 GGSVMDTCKAANLY 74
GGS MDT KAANL+
Sbjct: 136 GGSAMDTAKAANLF 149
>UniRef50_Q49A19 Cluster: ADHFE1 protein; n=13; Coelomata|Rep:
ADHFE1 protein - Homo sapiens (Human)
Length = 293
Score = 192 bits (469), Expect = 6e-48
Identities = 86/156 (55%), Positives = 113/156 (72%), Gaps = 1/156 (0%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
MTD N++ L P++ +DSL +NGI + VYD VRVEPTD SF +AI FA++G FD++VA+G
Sbjct: 79 MTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFMEAIEFAQKGAFDAYVAVG 138
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GG MDTCKAANLY S P ++FLDYV+AP+GKGK V++ +KP+IA+P
Sbjct: 139 GGCTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKPLIAVPTTSGTGSETTGVA 198
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLT-VPE 155
IFDYE + K GI+ A++P L LIDPLHT T +PE
Sbjct: 199 IFDYEHLKVKIGITSRAIKPTLGLIDPLHTSTCLPE 234
>UniRef50_UPI00015BAE59 Cluster: Alcohol dehydrogenase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: Alcohol dehydrogenase
- Ignicoccus hospitalis KIN4/I
Length = 414
Score = 175 bits (427), Expect = 7e-43
Identities = 97/242 (40%), Positives = 134/242 (55%), Gaps = 3/242 (1%)
Query: 23 GINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEF 82
G + +D V EP+ S ++A E DS +AIGGGS +DT K ANL +
Sbjct: 61 GKDVPYWDGVEPEPSAESVEEAAKALAESGADSVIAIGGGSALDTAKIANLL-ATYGGRV 119
Query: 83 LDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPIL 142
DYV P G+GK V VKPM+A+P + +++ K GIS + LRP L
Sbjct: 120 RDYVAPPYGEGKPVPGPVKPMVAVPTTAGTGSEVTSVAVVTLKDVGVKVGISSDFLRPSL 179
Query: 143 ALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISD 202
AL+DP T+TVP KV+ +G D HA+ES+ A P+ R P +PA RP Y GS ++D
Sbjct: 180 ALLDPELTMTVPPKVTADTGMDALTHAVESYIAKPYWAR-ERPEDPAKRPVYVGSFTVTD 238
Query: 203 VWARFCLQTLQKYFVRSV-NNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGN 261
A ++ + KY R+V D+EARS M +A+ +AG+ GNAGV L H +YP+ G
Sbjct: 239 ALAERAIELIGKYLRRAVYQGRTDLEARSGMLIASYLAGLAFGNAGVGLAHAASYPLGGR 298
Query: 262 VK 263
K
Sbjct: 299 YK 300
>UniRef50_A7D7U5 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Iron-containing alcohol dehydrogenase - Halorubrum
lacusprofundi ATCC 49239
Length = 474
Score = 146 bits (354), Expect = 5e-34
Identities = 85/269 (31%), Positives = 129/269 (47%), Gaps = 6/269 (2%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAK----EGNFDSF 56
+TD ++ SL + V D L +G + VYD V EP+ + ++ I F + E +D +
Sbjct: 92 VTDSDLVSLGHVDRVADELEADGFDVDVYDGVEREPSIEAVEECIAFVRDEMGEDGYDFY 151
Query: 57 VAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
+ +GGGS MDT KA ++ E LDYV AP G GK + P+I +P
Sbjct: 152 LGLGGGSCMDTAKATRAIVAN-GGEVLDYVAAPTGAGKNLTESGPPLILLPTTAGTGSEI 210
Query: 117 XXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
I E K GIS +R A++DP T T+P ++ + D HA+E +T
Sbjct: 211 SPVAILSVPEKGIKEGISSTHVRADAAVLDPTLTTTLPPDLTAKTAMDALGHAIEGYTTH 270
Query: 177 PFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAA 236
+ + P NPA RP Y G +++++ + L R VNN D+EAR +M A
Sbjct: 271 QYDDL-LRPENPADRPVYAGRTGFTEMFSEKAIDLLSSNVRRVVNNGDDIEARGAMLKGA 329
Query: 237 TMAGVGIGNAGVHLCHGLAYPIAGNVKSF 265
+ AG L H +AYP+ N ++
Sbjct: 330 LFGAIAGLTAGASLAHAMAYPVGNNYHTY 358
>UniRef50_A3ZRV1 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Blastopirellula marina DSM 3645|Rep:
Iron-containing alcohol dehydrogenase - Blastopirellula
marina DSM 3645
Length = 394
Score = 117 bits (281), Expect = 4e-25
Identities = 80/262 (30%), Positives = 121/262 (46%), Gaps = 9/262 (3%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + V +L GI +++D EP A A++ + +G
Sbjct: 38 VTDATLVRLGLVDKVRQALIDAGITVEIFDGSCAEPDLSVAVAAQAAAQKFGPHAICGLG 97
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + ++ E DY + G V P+IA+P
Sbjct: 98 GGSNIDLAKIVAILHAH-GGEAADYFSWDQVPGA-----VTPIIALPTTAGTGSEVSQSA 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E K LRP LA++DPL + T P +V+ SG D HA+E++T+ F
Sbjct: 152 VLTDIENAMKVSTLSQYLRPTLAIVDPLLSATCPPQVTADSGIDALTHAVEAYTSTTFDM 211
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
PA Y GS+P+ D A + + ++ V++V D+EAR+ M LAAT+AG
Sbjct: 212 LEHDSDAPA---PYSGSHPLVDALAEKAIALVGQHLVQAVRQGDDIEARTGMALAATLAG 268
Query: 241 VGIGNAGVHLCHGLAYPIAGNV 262
+ NAGV + H L YPI G V
Sbjct: 269 LAFSNAGVAVVHALEYPIGGAV 290
>UniRef50_Q6HZA9 Cluster: Alcohol dehydrogenase, iron-containing;
n=13; Bacillaceae|Rep: Alcohol dehydrogenase,
iron-containing - Bacillus anthracis
Length = 400
Score = 116 bits (280), Expect = 5e-25
Identities = 71/258 (27%), Positives = 123/258 (47%), Gaps = 24/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L ++ + L GI Y+KV EPT+ +A+ KEG D + +G
Sbjct: 37 VTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHVLEALTICKEGKCDFIIGLG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA + Y++ E DYV K + ++ P+IAIP
Sbjct: 97 GGSCIDAAKAVAVLYTN-GGEVEDYVQ----KDREIDNDPLPLIAIPTTSGTGSEVTSVA 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + K + H + P +A+IDP+ T +VP ++ +G D CHA+E++ +
Sbjct: 152 VITNKRTDVKMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYIS----- 206
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ S ++DV A ++++ KY + + ++EAR +M +A+ AG
Sbjct: 207 --------------KVSQSLTDVLALSAIESIMKYLRIAYEDGENMEAREAMMIASLQAG 252
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NA V L HG++ P+
Sbjct: 253 IAFSNASVTLVHGMSRPV 270
>UniRef50_Q5KYJ9 Cluster: Alcohol dehydrogenase; n=7;
Bacillaceae|Rep: Alcohol dehydrogenase - Geobacillus
kaustophilus
Length = 395
Score = 111 bits (268), Expect = 1e-23
Identities = 72/258 (27%), Positives = 122/258 (47%), Gaps = 24/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++DP + + + L + G+ + Y V EPTD K+A+ + D +A+G
Sbjct: 34 VSDPVMEKIGLVARCEQYLQQVGMTFAKYTGVDTEPTDVHVKEALDVCRSEQCDVIIALG 93
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA ++ ++ + DYV G K + P+IAIP
Sbjct: 94 GGSSIDAAKAVSVMMTN-EGTISDYV----GNQKRFTEKPLPLIAIPTTAGTGSEVTKVT 148
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ K IS AL P +A++DPL T++ P V+ +G D CHA+E++ +
Sbjct: 149 VIIDTKMDVKMMISQPALLPAVAIVDPLLTVSCPPSVTAATGVDALCHAIEAYIS----- 203
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ ++P++D A ++ + + R+ N D+EAR M +AA AG
Sbjct: 204 --------------RRAHPVTDALALSAIEAIVGHLRRAYENGQDIEAREKMAIAAMKAG 249
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NA V L HG++ PI
Sbjct: 250 MAFSNASVTLVHGMSRPI 267
>UniRef50_A5MZX1 Cluster: DhaT1; n=1; Clostridium kluyveri DSM
555|Rep: DhaT1 - Clostridium kluyveri DSM 555
Length = 382
Score = 111 bits (267), Expect = 2e-23
Identities = 73/249 (29%), Positives = 121/249 (48%), Gaps = 26/249 (10%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V DSL ++G+ Y ++DKV +P+ + + + AKE N D VA+GGGS +D KA ++
Sbjct: 51 VSDSLKKSGLEYVIFDKVESDPSVNTVRLGVETAKEKNIDVIVALGGGSALDAAKAISM- 109
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
S + LDY + KA I+ P++A+P I E K I
Sbjct: 110 VSTNGGDILDY------EKKAPEIEGIPIVALPTTAGTGSEVTKYSIITDTERKIKMLIG 163
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
++ L P +A++DP T +P V+ +G D F HA+E++ +
Sbjct: 164 NDFLIPKVAILDPNLTKMMPPSVTAATGMDAFTHAVEAYIS------------------- 204
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+ + P+ DV+A ++ + +++V D+EARS+M L AG+ NA V L H +
Sbjct: 205 KAAQPMCDVYAVKAIELITSNLIKAVLKEDDMEARSNMLLGQMYAGLAFSNASVALVHAM 264
Query: 255 AYPIAGNVK 263
+ P+ K
Sbjct: 265 SRPLGAYYK 273
>UniRef50_Q127Q6 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Burkholderiales|Rep: Iron-containing alcohol
dehydrogenase - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 418
Score = 111 bits (266), Expect = 2e-23
Identities = 75/249 (30%), Positives = 120/249 (48%), Gaps = 16/249 (6%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPT-DGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANL 73
++D L R GI+ ++D +P+ + + + H ++G D +A+GGGS +D K L
Sbjct: 61 LVDGLKRVGISSVMFDGGLPDPSLELCDRASAHLREQGAVDCVIAVGGGSNIDLAKVMTL 120
Query: 74 YYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
+ A YV P ++ + P+IA+P I + K +
Sbjct: 121 TLTSHHAA-AHYVGKP-----RLDTKPLPLIAMPTTAGTASEITPGAILVSGDGQTKVAV 174
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFT---AIPFTERGPAPANPAL 190
N LR +A+IDP TL+ P +V+ +G D HA+ESF A F G A
Sbjct: 175 MDNELRARIAVIDPELTLSCPPRVTADAGVDALTHAIESFITMDASDFNREGQAD----- 229
Query: 191 RPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHL 250
P Y G N ++ ++AR ++ + R+ D++AR+ M LA+ AG+ GNAG+H
Sbjct: 230 -PGYSGRNALTRIFAREAIRLCFAHLQRAYRCPDDIQARTGMALASLYAGMSYGNAGLHA 288
Query: 251 CHGLAYPIA 259
H LAY +A
Sbjct: 289 VHALAYGVA 297
>UniRef50_Q1NLZ5 Cluster: Iron-containing alcohol dehydrogenase;
n=2; cellular organisms|Rep: Iron-containing alcohol
dehydrogenase - delta proteobacterium MLMS-1
Length = 390
Score = 108 bits (260), Expect = 1e-22
Identities = 73/260 (28%), Positives = 122/260 (46%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+ DP V + + + SL + I +++KV EP A AK+ D + G
Sbjct: 39 VVDPGVVAAGMLPRLTASLEADSIPCTIHEKVDPEPGLKLADGAAKLAKQNKCDCVIGAG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD KA ++ ++ + DY+ G GK V P I +P
Sbjct: 99 GGSAMDVAKAVSILLTN-GGKAADYI----GLGKITKPGV-PKIMVPTTAGTGAEVTFTA 152
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+F EE +K G++ + L P A++DP TL++P +V+ +G D HALE++ +
Sbjct: 153 VFINEETSSKAGMNGDFLYPDAAILDPTLTLSIPPRVTAATGIDALTHALEAYVSTQ--- 209
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
++P+SD++A L+ + ++ N ++ ARS+M L + +AG
Sbjct: 210 ----------------AHPLSDMYALEALELIAANLGKACANGDNLAARSNMLLGSLLAG 253
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ AGV L H +AYP+ G
Sbjct: 254 KALATAGVGLVHAMAYPLGG 273
>UniRef50_Q11EZ5 Cluster: Iron-containing alcohol dehydrogenase;
n=5; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Mesorhizobium sp. (strain BNC1)
Length = 414
Score = 108 bits (259), Expect = 2e-22
Identities = 72/257 (28%), Positives = 115/257 (44%), Gaps = 10/257 (3%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
TD +A + KA++ ++ G+ ++ KV + + + + N D + IGG
Sbjct: 44 TDARMAQTAEFKAIMSAVAERGVQIHIFAKVEPDLPRSNIVEIVQRFGSENIDCVLGIGG 103
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GS +D K A + ++ + +Y + G + P+I +P +
Sbjct: 104 GSCLDAAKVAAVVLAN-GGDIREYFGEFLVPGPGL-----PVITVPTTGGTGAEVTCISV 157
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
+E K G++ L P A+IDP TLT P ++ +G D H +E+FTA +
Sbjct: 158 VYDDENQMKVGVASPHLEPYAAVIDPELTLTCPPALTAATGADALSHLIEAFTA---RVK 214
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
P A + Y G N ++DV+AR LQ L + V N D+ ARS M +AA AG+
Sbjct: 215 NPT-AEQIAKHLYVGKNLLTDVFARHGLQLLNGGLEKVVTNPSDLAARSDMMMAAYCAGM 273
Query: 242 GIGNAGVHLCHGLAYPI 258
I G H L PI
Sbjct: 274 AINTTGTAGAHALQSPI 290
>UniRef50_A1R2J5 Cluster: NAD(P)-dependent methanol dehydrogenase;
n=1; Arthrobacter aurescens TC1|Rep: NAD(P)-dependent
methanol dehydrogenase - Arthrobacter aurescens (strain
TC1)
Length = 395
Score = 105 bits (253), Expect = 9e-22
Identities = 76/261 (29%), Positives = 117/261 (44%), Gaps = 27/261 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A+ + AV +SL G++ V+D V PT A D V +G
Sbjct: 49 VTDPFLATTDVVAAVRESLEAAGLSVSVFDGVTPNPTTTCVDAGSDQAAASGVDVLVPVG 108
Query: 61 GGSVMDTCKAANLYYSDPD-AEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS MD K +L +P LDY N P++A+P
Sbjct: 109 GGSSMDAAKGISLGAVNPARGAGLDYSNH-------FENPALPIVAVPTTAGTGAEVNAF 161
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ E H K + H + P A++DP TL +P K + +G D HA+ES+++I
Sbjct: 162 GVVTDVEAHRKFYVGHESALPKAAVLDPELTLGLPPKATAATGMDALTHAIESYSSI--- 218
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
NP SD A + + ++ R+V + D+EARS + LA+ +A
Sbjct: 219 ----------------RQNPYSDGIALQVVSMVAEFLPRAVADGSDIEARSQLLLASHIA 262
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
GVG + G+ L H +A+P+ G
Sbjct: 263 GVGFSHTGLGLVHAIAHPLGG 283
>UniRef50_O67218 Cluster: 1,3 propanediol dehydrogenase; n=1;
Aquifex aeolicus|Rep: 1,3 propanediol dehydrogenase -
Aquifex aeolicus
Length = 387
Score = 105 bits (251), Expect = 2e-21
Identities = 70/247 (28%), Positives = 116/247 (46%), Gaps = 21/247 (8%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
+++SL +N I Y V+D++ PTD A D V IGGGSV+D KA ++
Sbjct: 51 LINSLKQNQIEYVVFDEITPNPTDKQVNKGAEIAVNEKVDFIVGIGGGSVLDAAKAISIV 110
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
S+ + DYV P G + + +P+I IP + K IS
Sbjct: 111 SSN-EGYAWDYVRYPEG-SRLIPFLNRPVITIPTTAGTGSEVNRYSVLTNPMTKEKMVIS 168
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
H+ P +AL+DP T ++P +++ +GFD HALES T
Sbjct: 169 HSLNYPKVALVDPELTYSMPPRLTALTGFDALMHALESLT-------------------N 209
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+ N I++ ++ ++ ++K+ + + EAR M AA +AG+ I + GV L H +
Sbjct: 210 KRENFIAEEYSVKAIELIRKWLPVAFEEPENKEARRYMSYAAMLAGIAIDHLGVALIHAM 269
Query: 255 AYPIAGN 261
+P++G+
Sbjct: 270 EHPVSGH 276
>UniRef50_Q898F2 Cluster: 1,3-propanediol dehydrogenase; n=6;
Clostridiaceae|Rep: 1,3-propanediol dehydrogenase -
Clostridium tetani
Length = 384
Score = 102 bits (244), Expect = 1e-20
Identities = 69/263 (26%), Positives = 118/263 (44%), Gaps = 26/263 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + +K V + L GI Y++YD + EPTD I + D +AIG
Sbjct: 35 VTDKIMIEIGNVKKVSEVLDDIGIKYEIYDGINSEPTDVMVDKGIEIYNNSHCDFLIAIG 94
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA ++ DY+ GK + ++AIP
Sbjct: 95 GGSPIDASKAIGAMITNL-GNINDYM------GKIIENASPSIVAIPTTAGTGSEATEFT 147
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I + + K + +L P LA++DP ++TVP+ ++ +G D HA+ES+T+
Sbjct: 148 IISNTKDNIKMLLKGKSLIPTLAIVDPQFSITVPQNITATTGIDALTHAIESYTS----- 202
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +N SD +A ++ + +++ + + EAR+ M L A AG
Sbjct: 203 --------------KHANSFSDTFALSAVKRIFNNLIKAYKDGKNFEARNEMALGALEAG 248
Query: 241 VGIGNAGVHLCHGLAYPIAGNVK 263
+ N+ V + HG++ PI K
Sbjct: 249 IAFNNSSVTIVHGMSRPIGALFK 271
>UniRef50_A6BZI7 Cluster: Putative iron alcohol dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Putative iron alcohol
dehydrogenase - Planctomyces maris DSM 8797
Length = 402
Score = 100 bits (240), Expect = 3e-20
Identities = 72/261 (27%), Positives = 113/261 (43%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +A+ + SL +GI ++D V PT + + A++ D V +G
Sbjct: 58 VTDKGLAAAGHEARAVASLEDSGIEITIFDDVHANPTTVDVERGLQVARQHQIDLIVGLG 117
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD K N ++ + DY G GKA + P+IA+P
Sbjct: 118 GGSSMDCAKGINFLLTN-GGKMEDYW----GVGKASKPML-PLIAVPTTAGTGSEAQSFA 171
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + E H K +A++DP TLT+P V++ +G D HALE+F P
Sbjct: 172 VIAHPETHMKMACGDKKAACRVAILDPELTLTMPRSVTHVTGIDALSHALETFVTKP--- 228
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
N IS +++R L F + +N+ D+ AR +M L A AG
Sbjct: 229 ----------------RNEISQLFSRRAWTLLANSFPQVLNSPNDLTARGNMQLGAHFAG 272
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
I N+ + H LA P++ +
Sbjct: 273 AAIENSMLGATHALANPLSAH 293
>UniRef50_A3DCF3 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
Iron-containing alcohol dehydrogenase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 389
Score = 99 bits (238), Expect = 6e-20
Identities = 69/247 (27%), Positives = 113/247 (45%), Gaps = 24/247 (9%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V SL NG+ +D V PT + + AK D + +GGGS +DT KA +
Sbjct: 51 VKKSLRENGVEVVHFDGVIPNPTTDVVTEGANMAKAAGVDVVIGLGGGSSIDTAKAIAVE 110
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
+ P + DY G A P+IAI + K+ I
Sbjct: 111 ATHPGTAW-DYNCHTPGPTSAT----LPIIAIGTTAGTGSQCTQCAVITKTSEKDKSAIW 165
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
H + P +A++DP T+T+P+ V+ +GFD F H E++ ++
Sbjct: 166 HKNIFPKVAIVDPEVTVTMPKSVTAQTGFDAFAHNFEAYLSVK----------------- 208
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
++P+ ++ A ++ +++Y +++ N D+EARS M LA T+ G+ NAGV L HGL
Sbjct: 209 --TSPLVEMMAIEAIKMIKEYLPKALENPNDIEARSKMSLADTLGGLTNSNAGVTLPHGL 266
Query: 255 AYPIAGN 261
+ G+
Sbjct: 267 GMQVGGH 273
>UniRef50_Q3Y3Q2 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Enterococcus faecium DO|Rep: Iron-containing
alcohol dehydrogenase - Enterococcus faecium DO
Length = 384
Score = 99.1 bits (236), Expect = 1e-19
Identities = 66/258 (25%), Positives = 121/258 (46%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + SL+ ++ VL SL + +K++D V EPTD +A+ F ++ ++DS +A+G
Sbjct: 34 ITDKLIVSLNLLEGVLASLKEENLTWKIFDGVDREPTDQIVAEALAFYQQEDYDSIIAVG 93
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA + ++ + A G+ + P+IAIP
Sbjct: 94 GGSCIDTAKAVAVLINNSGS------YAEFASGQLIAQNPLPLIAIPTTAGTGSEVTDVT 147
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + K + A A++DP + T P V+ +G D CHALES+ +
Sbjct: 148 VITDTQKDIKYMMKQAAFLSYAAIVDPQMSRTSPASVTAATGLDALCHALESYIS----- 202
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ + PI+ +++ ++ + + + + ++ AR ++ AA AG
Sbjct: 203 --------------KKAQPITRLFSLSAIKLIMENLPIAYSEPENLIARENLAQAAMEAG 248
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NA V L HG++ P+
Sbjct: 249 IAFSNASVTLIHGMSRPV 266
>UniRef50_A5UU06 Cluster: Iron-containing alcohol dehydrogenase;
n=5; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Roseiflexus sp. RS-1
Length = 390
Score = 98.7 bits (235), Expect = 1e-19
Identities = 68/261 (26%), Positives = 119/261 (45%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D + L + V L +GI VY V EP ++ + +EGN D VA+G
Sbjct: 38 VSDKIMLGLGLVGKVEQYLAESGIASTVYAGVNTEPVVEYVQEGLQTYREGNCDFVVAVG 97
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA + ++P Y +GK A + P++AIP
Sbjct: 98 GGSPIDTAKAIAVLVTNP-GSIEQYKG--IGKIAAPGV---PVVAIPTTAGTGSEATVYT 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ K I L P +A++DP+ T++ P+ V+ +G D HA+E++ ++
Sbjct: 152 VITDQKTDVKMLIGSPYLMPTIAIVDPMLTVSSPQSVTAATGVDALVHAIEAYVSVK--- 208
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P++D++ ++ + + ++ N ++EAR M L A AG
Sbjct: 209 ----------------RQPMTDIFCLSAIRLISQNIRQAWANGNNIEAREQMMLGAFQAG 252
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
V N+ V L HG++ PI +
Sbjct: 253 VAFSNSSVALVHGMSRPIGAH 273
>UniRef50_Q6LZ27 Cluster: Iron-containing alcohol dehydrogenase;
n=7; cellular organisms|Rep: Iron-containing alcohol
dehydrogenase - Methanococcus maripaludis
Length = 389
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/225 (27%), Positives = 106/225 (47%), Gaps = 20/225 (8%)
Query: 17 DSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYS 76
+ L G+ V+DKV P + FAKE + D VA+GGGS +D KA ++ +
Sbjct: 52 EQLKLAGVETVVFDKVEPNPLRSTVMAGGAFAKENDCDFIVALGGGSCIDASKAMSIMAT 111
Query: 77 DPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHN 136
+ D ++ DY+ GKG + + P++AI + +E K G +
Sbjct: 112 N-DGDYWDYIFGGTGKGMPLKAKPIPVVAITTTAGTGSETDPWAVVTHEINREKIGFGNE 170
Query: 137 ALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQG 196
P+LA++DP +VP K + Y GFD H++E + +I G
Sbjct: 171 DTFPVLAVVDPELMKSVPPKYTAYQGFDALFHSVEGYVSI-------------------G 211
Query: 197 SNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
+N +SD++A ++ + K ++V + D++AR + T++GV
Sbjct: 212 ANLMSDMYAITAIENVSKNLSKAVEDGNDMDAREKVAFGNTLSGV 256
>UniRef50_Q5QL37 Cluster: Alcohol dehydrogenase; n=1; Geobacillus
kaustophilus|Rep: Alcohol dehydrogenase - Geobacillus
kaustophilus
Length = 391
Score = 98.3 bits (234), Expect = 2e-19
Identities = 71/261 (27%), Positives = 121/261 (46%), Gaps = 24/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + + ++ SL + I Y VY V +P+ + KE FD VAIG
Sbjct: 47 VTDRGVEATGLLAGIIQSLESSNIQYCVYADVEPDPSLETIDQGAAAFKEQPFDCIVAIG 106
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT K + ++ DY K K+ ++ P+IA+P
Sbjct: 107 GGSPIDTAKGIRVVATN-GGSIGDYAGVNRIKKKS---EI-PLIALPTTSGTGSEVTIFG 161
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
++ + + K ++ + P +AL+DP T+++P+K++ SG D H +E+F F+
Sbjct: 162 VYSDWKNNVKVTVTSPYMAPEIALVDPKLTMSLPKKITAASGIDALAHGIETF----FSL 217
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
R S PISDV A + T+ +Y R+V + + EAR M + +AG
Sbjct: 218 R---------------SQPISDVLAIEAMTTVNRYLRRAVEDGTNKEARIGMSYGSLLAG 262
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
+ N + L H + ++G+
Sbjct: 263 MAFNNGFLGLAHAIGSALSGH 283
>UniRef50_Q5KYT0 Cluster: Alcohol dehydrogenase; n=3;
Bacillaceae|Rep: Alcohol dehydrogenase - Geobacillus
kaustophilus
Length = 395
Score = 98.3 bits (234), Expect = 2e-19
Identities = 69/260 (26%), Positives = 121/260 (46%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + L ++ V L + G + VY V EP + + A+ F ++G FD + +G
Sbjct: 37 ITDPALEKLGLVEQVASPLRQAGCSVHVYTDVVPEPPLETGEKAVAFVRDGEFDLVIGVG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD K A + + + DY+N + + + + P I IP
Sbjct: 97 GGSAMDLAKLAAV-LAVHEGSVADYLN--LTGTRTLEKKGLPKILIPTTSGTGSEVTNIS 153
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E K ++H+ L +A++DP T++VP +V+ +G D HA+E++ ++
Sbjct: 154 VLSLET--TKDVVTHDYLLADVAIVDPQLTVSVPPRVTAATGIDALTHAVEAYVSV---- 207
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
++P SD A ++ + + ++V + D +AR M + +AG
Sbjct: 208 ---------------NASPTSDGLALQAMRLISRSLRKAVEHGADKQARIDMANGSYLAG 252
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NAGV H LAYP+ G
Sbjct: 253 LAFFNAGVAGVHALAYPLGG 272
>UniRef50_Q8DM94 Cluster: CoA-linked acetaldehyde dehydrogenase and
iron-dependent alcohol dehydrogenase /
pyruvate-formate-lyase deactivase; n=15; cellular
organisms|Rep: CoA-linked acetaldehyde dehydrogenase and
iron-dependent alcohol dehydrogenase /
pyruvate-formate-lyase deactivase - Synechococcus
elongatus (Thermosynechococcus elongatus)
Length = 885
Score = 97.9 bits (233), Expect = 2e-19
Identities = 71/265 (26%), Positives = 120/265 (45%), Gaps = 27/265 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + ++ +L GI Y ++ +V +PT + + ++ D VA+G
Sbjct: 491 VTDKPLFDLGITEPIVHTLEELGIKYDIFHEVEPDPTLSTVNRGLGLLRQYQPDVIVAVG 550
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKP------MIAIPXXXXXXX 114
GGS MD K L Y P+ EF + K V Q+ P ++AIP
Sbjct: 551 GGSPMDAAKVMWLLYEHPEVEFDGLAMRFMDIRKRV-YQLPPLGQKAILVAIPTTSGTGS 609
Query: 115 XXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFT 174
+ + + K ++ AL P +A++DP L +P+K++ Y G D HALE++
Sbjct: 610 EVTPFAVVTDDRVGIKYPLADYALTPTMAIVDPDLVLHMPKKLTAYGGIDALTHALEAYV 669
Query: 175 AIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVN-NSGDVEARSSMH 233
++ TE ++ A ++ L Y R+ + D EAR +H
Sbjct: 670 SVLSTE-------------------FTEGLALEAIKLLFTYLPRAYRLGAADPEAREKVH 710
Query: 234 LAATMAGVGIGNAGVHLCHGLAYPI 258
AAT+AG+ NA + +CH LA+ +
Sbjct: 711 YAATIAGMAFANAFLGVCHSLAHKL 735
>UniRef50_Q6AQV2 Cluster: Related to 1,3-propanediol dehydrogenase;
n=2; Desulfotalea psychrophila|Rep: Related to
1,3-propanediol dehydrogenase - Desulfotalea
psychrophila
Length = 387
Score = 97.9 bits (233), Expect = 2e-19
Identities = 69/263 (26%), Positives = 112/263 (42%), Gaps = 25/263 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +ASL AV ++L GI + +Y K +EP S + AKE D + G
Sbjct: 39 VTDPGLASLGLHIAVEEALAHAGIEFVLYAKAELEPNATSIQHCADVAKEFKADVIIGFG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KAA++ + + Y V G + P+IA+P
Sbjct: 99 GGSALDTAKAASV-LAVHEGPISKYFGVDVVPGPCM-----PLIAVPTTAGTGSEMTSIS 152
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E AK GI + + ++DP T +P ++ +G D F HA+ESF +
Sbjct: 153 VLTNNETGAKLGIVSDYIYASAVILDPALTTGLPPHITAMTGVDAFVHAMESFVGLM--- 209
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
S P +D ++ + K ++ N ++EAR +M + +AG
Sbjct: 210 ----------------STPFTDALNLQAMKIIAKNIRKAYANGNNLEAREAMLYGSALAG 253
Query: 241 VGIGNAGVHLCHGLAYPIAGNVK 263
+G GN + H + + K
Sbjct: 254 MGFGNTQNGVIHAVGTSVPAKYK 276
>UniRef50_Q1QCB5 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Psychrobacter cryohalolentis (strain K5)
Length = 387
Score = 97.1 bits (231), Expect = 4e-19
Identities = 70/261 (26%), Positives = 123/261 (47%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + +SL + GIN ++D+V +P ++AI A+ + + +G
Sbjct: 38 ITDTGICELGYVDIAQESLEQAGINVVIFDRVVADPPIEVVEEAIELARANQCNLVIGLG 97
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT K LY +D + + + A + K + P+ AIP
Sbjct: 98 GGSPIDTAKIVALYPNDFQS-VNELLEADISGFKKM-----PLFAIPTTAGTGAEATFVS 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ +K I + P +A++D TL +P ++ + D H +E++T+ T+
Sbjct: 152 VITAKD-GSKKAIYTPKILPDVAILDATLTLKLPRHITAATALDAMVHCIEAYTS--RTK 208
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ NPISD A LQ L F +++ D++AR+ M L +T+AG
Sbjct: 209 K----------------NPISDALAVKGLQMLWSNFYTVLHHGDDIDARADMLLGSTLAG 252
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
+ NA V HGL+YP++ N
Sbjct: 253 IAFVNASVAAVHGLSYPLSIN 273
>UniRef50_Q67MQ9 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Iron-containing
alcohol dehydrogenase - Symbiobacterium thermophilum
Length = 394
Score = 96.3 bits (229), Expect = 7e-19
Identities = 59/212 (27%), Positives = 98/212 (46%), Gaps = 23/212 (10%)
Query: 49 KEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPX 108
+E DS +A+GGGSV+DT K + + + Y+ A + + K + P+ +P
Sbjct: 88 REAGCDSIIALGGGSVIDTAKGLRVLIGQETDDIMQYMGADILQPK----RRVPLAVVPT 143
Query: 109 XXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCH 168
+ + E K + L P LA++DP T ++P +++ +G D H
Sbjct: 144 TAGTGSEATLVAVIAHPERQVKMEFVSHHLLPDLAVLDPRMTRSLPPRITASTGMDALVH 203
Query: 169 ALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEA 228
A+E +T+I NP+SD +A ++ +++Y R+V N D EA
Sbjct: 204 AIEGYTSIQ-------------------RNPLSDAYAWAAIELIREYLPRAVANGQDTEA 244
Query: 229 RSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
R +M AA MAG NA V L H + + + G
Sbjct: 245 RLAMANAALMAGAAFSNAMVGLVHAIGHAVGG 276
>UniRef50_A6VXN3 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Marinomonas sp. MWYL1|Rep: Iron-containing alcohol
dehydrogenase - Marinomonas sp. MWYL1
Length = 388
Score = 95.9 bits (228), Expect = 1e-18
Identities = 68/260 (26%), Positives = 115/260 (44%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + A +SL + G+ Y +Y V P+ DA+ F K+ N D+ + IG
Sbjct: 37 VTDKGLVDSGTLNAFFESLDQAGLKYDLYQDVEPNPSSTVIDDAVAFLKQSNCDAIIGIG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA ++P LDY G K +N P+ AIP
Sbjct: 97 GGSSIDAAKAVAAMATNP-GSILDY----EGFDKLIN-DPMPLFAIPTTAGTGSECTAST 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + H KT I L P +A++D T+ +P ++ +G D HA+ES+ +
Sbjct: 151 VVTNPKNHFKTAIISPRLFPKMAILDAELTIQLPPAITASTGMDALTHAIESYVS----- 205
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +NPIS +A ++ + K ++ DV AR +M +A+ +AG
Sbjct: 206 --------------KMANPISRAFALEAIKMITKNIKKAYFVGTDVAARENMLVASFLAG 251
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
V + + H +++ G
Sbjct: 252 VAFSLSKLGNVHAISHTFGG 271
>UniRef50_A4L2U7 Cluster: Alcohol/acetaldehyde dehydrogenase; n=10;
Lactobacillus|Rep: Alcohol/acetaldehyde dehydrogenase -
Lactobacillus reuteri
Length = 878
Score = 95.5 bits (227), Expect = 1e-18
Identities = 67/266 (25%), Positives = 119/266 (44%), Gaps = 27/266 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTR--NGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
+T P ++ ++ V+D L + N + V+D V +P+ + + + + D+ +A
Sbjct: 498 VTGPGMSKRGYVQRVIDQLRQRQNNTAFLVFDDVEEDPSTNTVEKGVAMMNDFKPDTIIA 557
Query: 59 IGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKP----MIAIPXXXXXXX 114
+GGGS MD KA ++Y P+ + + + K KP +I IP
Sbjct: 558 LGGGSPMDAAKAMWMFYEHPETSWYGVMQKYLDIRKRAYQIKKPTKSQLIGIPTTSGTGS 617
Query: 115 XXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFT 174
+ E H K ++ AL P +A++D TVP K + ++G D+ CHA ES+
Sbjct: 618 EVTPFAVITDSETHVKYPLADYALTPNIAIVDSQFVETVPAKTTAWTGLDVLCHATESYV 677
Query: 175 AIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHL 234
++ T+ + W+ ++ + + +SV GD AR MH
Sbjct: 678 SVMATD-------------------YTRGWSLQTIKGVMENLPKSV--QGDKLARRKMHD 716
Query: 235 AATMAGVGIGNAGVHLCHGLAYPIAG 260
+TMAG+ G A + + H LA+ + G
Sbjct: 717 FSTMAGMAFGQAFLGINHSLAHKMGG 742
>UniRef50_A5KMH6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 420
Score = 93.9 bits (223), Expect = 4e-18
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 23/260 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+T P + + VL+ + G+ Y +Y+KV PTD + +DA+ E D +A+G
Sbjct: 58 VTGPTLIGRGLLDGVLEEMEEQGLLYVIYNKVEQNPTDENVEDAVKVFLENGCDCMLALG 117
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GG+ +D KA + P+ + + G + V Q+ + A+P
Sbjct: 118 GGAPLDCAKAVGARIARPNRQ----IRQLQGLFRVVK-QIPMLFAVPTTAGSGSETTISA 172
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ H K I+ L P A++DP TL +P V+ +G D CHA+E++T +
Sbjct: 173 VITDTATHHKAAINDLRLMPKYAVLDPELTLGLPPDVTAMTGMDALCHAVEAYTNDKY-- 230
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
++ R ++ + + ++ N D+EAR M AA AG
Sbjct: 231 ----------------NSDTERELCRKAVRLIYENLLKVYENGSDIEARQKMQQAAFYAG 274
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
GV H + + + G
Sbjct: 275 RAFTRGGVGYVHAIGHAVGG 294
>UniRef50_UPI0000498B44 Cluster: alcohol dehydrogenase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: alcohol
dehydrogenase - Entamoeba histolytica HM-1:IMSS
Length = 419
Score = 93.5 bits (222), Expect = 5e-18
Identities = 75/270 (27%), Positives = 125/270 (46%), Gaps = 32/270 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTR--NGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
++D + L ++ V++ L R N + ++Y V +EPT + +A++ D+ +A
Sbjct: 46 VSDRMIYKLGYVERVMEVLKRRRNQVEIEIYIDVPIEPTTKAITEALNVMNTFGPDNIIA 105
Query: 59 IGGGSVMDTCKAANLYYSDPDAEFLDY------VNAPVGKGKAVNIQVKPMIAIPXXXXX 112
IGGGSVM K + Y P+ + D + V G V + + +I +P
Sbjct: 106 IGGGSVMCVAKIMWMLYEHPELKLQDIPTQFADIKENVFSGPEVGEKAR-LICVPTTSGN 164
Query: 113 XXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALES 172
I E+ + I+H L P +A++DP T TVP++ +GFD+ H++E+
Sbjct: 165 GSEVSPFCILVDEKTNTTYPIAHYNLIPSVAIVDPEFTYTVPKRTLADNGFDMLSHSIEA 224
Query: 173 FTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNN-SGDVEARSS 231
+ S +D CL+ LQ F VN +G AR++
Sbjct: 225 YI----------------------STYANDFANGMCLEALQLIFKNLVNGYNGCSCARAN 262
Query: 232 MHLAATMAGVGIGNAGVHLCHGLAYPIAGN 261
+H A+T+AG+ GNA + L H LAY IA +
Sbjct: 263 LHNASTIAGMAHGNAYLGLVHALAYKIANH 292
>UniRef50_Q98B58 Cluster: Alcohol dehydrogenase; n=8;
Alphaproteobacteria|Rep: Alcohol dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 408
Score = 93.1 bits (221), Expect = 7e-18
Identities = 68/256 (26%), Positives = 112/256 (43%), Gaps = 10/256 (3%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
TD A + ++ SL I V+D+V + S + A++ + + IGG
Sbjct: 38 TDERFAGTAVFAEIVQSLQAASIEVLVHDRVLPDVPRDSVGICVDEAEKFQPEMVIGIGG 97
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GS +D K A+L S + DY G + P+IA+P +
Sbjct: 98 GSCLDFAKCADLLLSH-GGKLQDYYGEFKVPGPTL-----PLIAVPTTAGTGSEVTPVAV 151
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
+ K GIS L +AL DP T+T P ++ +G D HA+E+FTA +R
Sbjct: 152 ISDPDRTLKVGISSPYLIAAVALCDPELTMTCPPALTAIAGADALTHAIEAFTA---KQR 208
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
G P + A + + G ++D +A ++ L + ++ + D +AR+ + + A AG
Sbjct: 209 GEDP-SLAQQHVFIGKTALTDHFALLAIKLLGRSLEKACTDGTDADARADVMMGALAAGC 267
Query: 242 GIGNAGVHLCHGLAYP 257
G AG H + YP
Sbjct: 268 AFGTAGTAAAHAVQYP 283
>UniRef50_A6NTK3 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 377
Score = 91.9 bits (218), Expect = 2e-17
Identities = 64/258 (24%), Positives = 118/258 (45%), Gaps = 36/258 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +A + V D+L + G +K++ V+ +P + + +E DS +A G
Sbjct: 29 VTDRFMAESGRISYVTDTLDKAGAEWKLFSDVQADPDVATVTKGVGIIQEFKPDSVIAFG 88
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA +Y+++ K N+ IAIP
Sbjct: 89 GGSAIDAAKAI-VYFAN----------------KTQNVGECKFIAIPTTSGTGSEVTRFA 131
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E K + ++L P +A++DP T++VP ++ +G D+F HA+E+F
Sbjct: 132 VITNREKGVKYPLIDDSLLPDVAILDPQLTVSVPPAITADTGLDVFTHAVEAFVC----- 186
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+N +D A ++ ++++ + + + D+EAR MH A+ +AG
Sbjct: 187 --------------TAANDFTDAAAEKSIKLVRRHLLNAYQHPDDLEARQGMHNASCLAG 232
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NAG+ L HG+A+ +
Sbjct: 233 IAFSNAGLGLNHGMAHAL 250
>UniRef50_A3UHY4 Cluster: Putative uncharacterized protein; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Putative
uncharacterized protein - Oceanicaulis alexandrii
HTCC2633
Length = 380
Score = 91.9 bits (218), Expect = 2e-17
Identities = 71/260 (27%), Positives = 111/260 (42%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V A L L G+ VYDKV +P + + +A+ +E ++ + G
Sbjct: 40 VTDQGVLKAGLADAALAGLKDAGLQVHVYDKVVADPPESTVFEAVAEGQEFGAEAVIGFG 99
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT K L S + ++ G + V P+I +P
Sbjct: 100 GGSPMDTAKVVALLLSGEQS-----LSTMYGV-QQVRANRPPLILLPTTAGTGSEVTNVA 153
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ +K GI+ + L +A++DP TL +P+ + Y+G D HA+E+FT
Sbjct: 154 VLT-TGATSKRGIAADPLYADMAILDPDLTLGLPKHPTAYTGIDAMVHAIEAFT------ 206
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ NP+SD A L+ L +R+ + D EAR M L A +AG
Sbjct: 207 ------------NRRSKNPMSDALALTALKLLHGSILRACEDGSDREARGDMLLGAMLAG 254
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
N+ H +AYP+ G
Sbjct: 255 QAFSNSPCAGVHAMAYPLGG 274
>UniRef50_A1I9B7 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
Iron-containing alcohol dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 394
Score = 91.9 bits (218), Expect = 2e-17
Identities = 60/261 (22%), Positives = 115/261 (44%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINY-KVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+TD V + +K V +++ +G++ VYD+ V+ + + +E DS +A+
Sbjct: 39 VTDKGVVNAGLVKVVEENVAGSGVSIGAVYDETPVDSSIHAVNAIAAIYREKGCDSIIAV 98
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGS +DT K N+ S+ + + + V +KP + IP
Sbjct: 99 GGGSAIDTAKGVNIVLSENTDDLMKFTG-----NNRVRAVMKPFVVIPTTGGTGSEVTMA 153
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ ++ K + + P ++DP T T+P K++ +G D HA+E+F +I
Sbjct: 154 AVIANPDLGVKMQFTTPLMLPDFTILDPRMTKTMPPKITAATGMDAMTHAVETFMSIQ-- 211
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
NP+SD +A ++ L ++V + D + R ++ A +A
Sbjct: 212 -----------------RNPVSDAFAWSAIELLVANLPKAVTDGDDEDVRLAVATGAMLA 254
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
G+ N+ V + H +A+ + G
Sbjct: 255 GIAFSNSMVGVVHAVAHALGG 275
>UniRef50_UPI000038E2A2 Cluster: hypothetical protein Faci_03000161;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000161 - Ferroplasma acidarmanus fer1
Length = 414
Score = 91.5 bits (217), Expect = 2e-17
Identities = 69/244 (28%), Positives = 112/244 (45%), Gaps = 24/244 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAK-EGNFDSFVAI 59
+TDPNV + + SL++ I Y+VYDK+ EPT + +A+ FA+ G FDS VA+
Sbjct: 47 VTDPNVYKFGLLNDIETSLSKFQIKYEVYDKISNEPTMENIVNAVEFARSNGKFDSVVAV 106
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGSV+DT K ++ E +Y+ K K + P I IP
Sbjct: 107 GGGSVLDTSKMVASMVTN-KGEPAEYLTPVEDKFKNPGL---PKILIPTTGGTGSEVSNM 162
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ E KT + + L A++DP+ ++ P + + SG D H +E +
Sbjct: 163 SVVINRESMYKTWAASSNLLADTAIVDPVLNVSAPPRTTAASGMDALAHNIEGLIS---- 218
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ +NPISD A + + + N+ ++EARS+M ++A +
Sbjct: 219 ---------------KEANPISDGMATKAASLIFRNLRTAYNDPSNMEARSAMSMSAMLG 263
Query: 240 GVGI 243
G+ I
Sbjct: 264 GMVI 267
>UniRef50_Q1FNN5 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Clostridium phytofermentans ISDg|Rep:
Iron-containing alcohol dehydrogenase - Clostridium
phytofermentans ISDg
Length = 378
Score = 91.5 bits (217), Expect = 2e-17
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 37/256 (14%)
Query: 3 DPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGG 62
DP +A + + D L G +++V+ +V +PT AI D+ +A+GGG
Sbjct: 33 DPFMAQSGKVNLITDILIEMGSSFEVFSEVVPDPTIQVVSKAIGGMNSFKPDTVIALGGG 92
Query: 63 SVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIF 122
S +DT KAA+ YS +G K +IAIP +
Sbjct: 93 SAIDTAKAASNIYSQ------------MGNEKLF------LIAIPTTSGTGSEVTNFSVI 134
Query: 123 DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERG 182
+ AK + +++ P A +DP T++VP +++ +G D+ HALE++ + T G
Sbjct: 135 SDPQAQAKYPLRSDSMVPDAAFLDPRFTVSVPPQITADTGMDVLTHALEAYVS---TNAG 191
Query: 183 PAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVG 242
+D A ++ + Y R+V D+EAR+ MH A+ +AGV
Sbjct: 192 ----------------DFTDACAEKAVRLVWNYLARTVEEGSDMEARTHMHNASCLAGVA 235
Query: 243 IGNAGVHLCHGLAYPI 258
A + LCH +A+ +
Sbjct: 236 FNGASLGLCHSMAHAL 251
>UniRef50_Q9WWD4 Cluster: AttL; n=42; Proteobacteria|Rep: AttL -
Agrobacterium tumefaciens
Length = 386
Score = 91.1 bits (216), Expect = 3e-17
Identities = 70/262 (26%), Positives = 110/262 (41%), Gaps = 27/262 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + +K + D+L +G N ++DKV +P + D + A++ D + +G
Sbjct: 40 ITDAGLIKAGLIKPIADALAASGFNVTIFDKVVADPPEHIVADCVESARQIGVDIVIGLG 99
Query: 61 GGSVMDTCK-AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS +D K A L S D D KG + P++ +P
Sbjct: 100 GGSSLDIAKLVAVLLVS--DQTLADMYGIGNVKGSRL-----PLVLVPTTAGTGSEVTNI 152
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
I E K G+ L L+D T+ +P+ + +G D HA+E++T
Sbjct: 153 SIITTGET-TKMGVVSPQLYADFVLLDAELTVGLPQVHTAATGIDAMVHAIEAYT----- 206
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ NP+SD AR L+ L + + N D +AR M L AT+A
Sbjct: 207 -------------SKHKKNPLSDALAREALRLLGANLIAACRNGADRKAREGMLLGATLA 253
Query: 240 GVGIGNAGVHLCHGLAYPIAGN 261
G N+ V H LAYP+ G+
Sbjct: 254 GQAFANSPVAAVHALAYPLGGH 275
>UniRef50_Q578L7 Cluster: Alcohol dehydrogenase, iron-containing;
n=7; Alphaproteobacteria|Rep: Alcohol dehydrogenase,
iron-containing - Brucella abortus
Length = 389
Score = 90.6 bits (215), Expect = 4e-17
Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 21/258 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A L + + L L G+ Y V+ V+ P + + + +EG D +A G
Sbjct: 39 VTDPGLAKLPVVASTLAVLDAAGVQYGVFSDVKPNPVESNLHAGVKVFREGRHDGVIAFG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + + D+ + +A + + P+IA+P
Sbjct: 99 GGSALDLGKLI-AFQAGQTRPVWDFEDIGDWWTRADSNAIAPVIAVPTTAGTGSEVGRAG 157
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E H K I H + P+ + DP + +P ++ +G D H LE++ A
Sbjct: 158 VLTNESTHTKKVIFHPKMLPVTVIADPELSTGMPPFITAGTGMDALAHCLEAYCA----- 212
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P P G I+ R + L K + N GD+EAR++M AA M G
Sbjct: 213 -------PGFHPMADG---IAVEGIRLVFENLPKAYA----NGGDIEARANMMAAAAM-G 257
Query: 241 VGIGNAGVHLCHGLAYPI 258
G+ H L++PI
Sbjct: 258 ATAFQKGLGAIHSLSHPI 275
>UniRef50_Q30W85 Cluster: Alcetaldehyde dehydrogenase or
NADPH-dependent butanol dehydrogenase; n=1;
Desulfovibrio desulfuricans G20|Rep: Alcetaldehyde
dehydrogenase or NADPH-dependent butanol dehydrogenase -
Desulfovibrio desulfuricans (strain G20)
Length = 369
Score = 90.2 bits (214), Expect = 5e-17
Identities = 61/260 (23%), Positives = 118/260 (45%), Gaps = 35/260 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + + ++ L GI ++V+D V +P+ + H + + ++ +A+G
Sbjct: 31 VTDPFMVKTGFIDRLISHLDLGGIRHRVFDGVEPDPSLETVTKGTHLYMQDHAEAVIALG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA + S D P+ ++AIP
Sbjct: 91 GGSAIDAAKAIAFFASKVDTSR----PRPI------------LVAIPTTSGTGSEVTAIS 134
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + K ++ L P LA++D T T+P V++ +G D+ HA+E++T+
Sbjct: 135 VVTDKVNEVKIPLNDEQLIPDLAILDARFTRTLPPSVTSVTGMDVLTHAIEAYTS----- 189
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +N + ++A + ++ + +Y R+ S D+EAR M LA+ MAG
Sbjct: 190 --------------RKANAFTSIYAEYAIRYVFEYLPRAYRCSDDMEAREKMLLASCMAG 235
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ N+G+ + H +A+ + G
Sbjct: 236 MAFNNSGLGITHSIAHSLGG 255
>UniRef50_A5MYY1 Cluster: Putative uncharacterized protein; n=1;
Clostridium kluyveri DSM 555|Rep: Putative
uncharacterized protein - Clostridium kluyveri DSM 555
Length = 384
Score = 89.8 bits (213), Expect = 6e-17
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 23/250 (9%)
Query: 13 KAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAAN 72
K + +L + ++ + EPT A K D +A+GGGS +D CKA
Sbjct: 48 KIFISNLMDKDFDVTLFTDIIPEPTVKVVDRAAEVLKSSCSDVVIAVGGGSTIDICKAIC 107
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
+ ++ + +Y+ K V + P+I +P + EE + K
Sbjct: 108 MLKNN-EGSVKEYL---FNGNKTVENKSLPLIVVPTTAGSGSEVTAASVISDEENNIKLS 163
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
++HN L P +A++DP ++P+ V+ +G D HA+E++ +
Sbjct: 164 VTHNYLIPEIAVLDPAMQTSMPQLVTASTGMDALTHAIEAYVS----------------- 206
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
+ ++ ISD +A ++ + K +V ++EAR M +A+T+A V NAG+ H
Sbjct: 207 --KNASIISDTYAEKSIELIGKNIYTAVFTPDNLEARGKMAVASTLAAVAFANAGLGAVH 264
Query: 253 GLAYPIAGNV 262
G++ + G V
Sbjct: 265 GISQAMGGIV 274
>UniRef50_A5YT21 Cluster: Alcohol dehydrogenase; n=1; uncultured
haloarchaeon|Rep: Alcohol dehydrogenase - uncultured
haloarchaeon
Length = 399
Score = 89.8 bits (213), Expect = 6e-17
Identities = 56/184 (30%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + + S+ I Y +YD V+ PT+ DA+ + G+ D VA+G
Sbjct: 39 ITDQGIRKAGILDIIETSIEGENITYDIYDNVKPNPTESMVSDALSVLESGDHDVVVAVG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDY-VNAPVG-KGKAVNIQVKPMIAIPXXXXXXXXXXX 118
GGSV+DT K A L ++ D +Y VN P + Q P+I IP
Sbjct: 99 GGSVIDTAKCATLLKTN-DLPLSEYEVNTPADVTAGTIESQTHPLITIPTTAGTGSEVDY 157
Query: 119 XXIFDYEEIHAKTGISHNALRP-------ILALIDPLHTLTVPEKVSNYSGFDIFCHALE 171
+ EE K I L P ++L+DP T ++P + + +GFD F HALE
Sbjct: 158 WAVITAEERQFKMAIGQPPLSPGGPYLGADISLVDPELTASLPPRQTAATGFDAFSHALE 217
Query: 172 SFTA 175
+ A
Sbjct: 218 NHVA 221
>UniRef50_A6W0M4 Cluster: Iron-containing alcohol dehydrogenase;
n=13; Bacteria|Rep: Iron-containing alcohol
dehydrogenase - Marinomonas sp. MWYL1
Length = 386
Score = 89.4 bits (212), Expect = 8e-17
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L ++ + D L+ +G V+D EPT S + + + ++D VA+G
Sbjct: 36 ITDRMMVQLGYVQKIQDLLSVDGFEVDVFDGTEPEPTAASIEAGVQCVIDNSYDVIVALG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D+ KA + + DY P + VN P+IAIP
Sbjct: 96 GGSPIDSAKAIAILGKN-GGNIRDY-KFP----RQVNETGIPIIAIPTTAGTGSEVTRFT 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E+ K P A++D TL++P +++ +G D HA+E++ +
Sbjct: 150 IITDEKNDEKMLCVGIGFMPFAAIVDVNLTLSLPPRITADTGIDALTHAIEAYVS----- 204
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
Q ++P SD A ++ + + N ++EAR +M L +T+AG
Sbjct: 205 --------------QKASPFSDCQALSAMRLIGPNLKEAYINGNNIEAREAMMLGSTLAG 250
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ +A V L HG++ PI
Sbjct: 251 IAFSSASVALVHGMSRPI 268
>UniRef50_Q9YAH6 Cluster: Alcohol dehydrogenase; n=1; Aeropyrum
pernix|Rep: Alcohol dehydrogenase - Aeropyrum pernix
Length = 390
Score = 89.0 bits (211), Expect = 1e-16
Identities = 68/265 (25%), Positives = 122/265 (46%), Gaps = 26/265 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHF-AKEGNFDSFVAI 59
+TD VA++S K ++ + G+ ++D V EP + DAI A+ ++ VA+
Sbjct: 35 VTDGKVAAMSWFKEAVEHVASLGVEVCIFDGVTPEP-EFDVGDAIASEARRCRAEAIVAV 93
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGSV+D KA + + PDA+ AP + + ++A+P
Sbjct: 94 GGGSVIDAAKAGFVKFVRPDADLEGL--APFNYLGLEDSGIV-LVAVPTTSGTGSDASYG 150
Query: 120 XIFDYEEI--HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
+ K + + P +++DP TL +PE+++ + D H++E+
Sbjct: 151 IVLTKRVNGGREKIAVGSYEVVPYASILDPSITLGMPERLTVGTAVDALAHSVEAI---- 206
Query: 178 FTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAAT 237
A +NP+SD A + + + VN+ G+ +AR+ MH+AAT
Sbjct: 207 ---------------ASTNANPLSDALAAKAAEIVFRRLPEVVNDPGNYDARAEMHIAAT 251
Query: 238 MAGVGIGNAGVHLCHGLAYPIAGNV 262
MAG+ N+G+ L H +A+P+ +
Sbjct: 252 MAGMAFTNSGLGLAHAIAHPLGARL 276
>UniRef50_P71017 Cluster: Alcohol dehydrogenase; n=9; Bacillus|Rep:
Alcohol dehydrogenase - Bacillus subtilis
Length = 402
Score = 89.0 bits (211), Expect = 1e-16
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 22/260 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + V++SL GI +++KV P + K+ N + VA+G
Sbjct: 47 VTDPGIYKAGVADPVIESLKEAGIEVVLFNKVEPNPPVRLVNEGSELYKKENCNGLVAVG 106
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT KA + + + LDY A GK K + ++ P+ IP
Sbjct: 107 GGSSMDTAKAIGV-EATHEGSVLDY-EAADGK-KPLENRIPPLTTIPTTAGTGSEVTQWA 163
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ EE K + L +IDP +++P V+ +G D HA+E +T + F +
Sbjct: 164 VITDEEREFKFNTGGPLIAAHLTIIDPELHVSMPPHVTAMTGIDALAHAIECYT-MKFAQ 222
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
PI+D A ++ Y R+ + D+EAR M AA +AG
Sbjct: 223 ------------------PITDAVALMAIEYAAHYIKRAFADGEDLEARYGMAQAAMLAG 264
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ G+ H ++ + G
Sbjct: 265 LSYGSESAGAAHAMSQTLGG 284
>UniRef50_Q87IP0 Cluster: Alcohol dehydrogenase; n=17; cellular
organisms|Rep: Alcohol dehydrogenase - Vibrio
parahaemolyticus
Length = 382
Score = 88.6 bits (210), Expect = 1e-16
Identities = 70/263 (26%), Positives = 110/263 (41%), Gaps = 31/263 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + +K V D LT G+ V+D + PT + D + KE D +++G
Sbjct: 36 VTDKILNQIGVVKQVQDLLTERGVATVVFDGTQPNPTITNVNDGLALLKENECDFVISLG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPM---IAIPXXXXXXXXXX 117
GGS D K L S+ +G + V+ KPM IAI
Sbjct: 96 GGSPHDCAKGIALVASN---------GGKIGDYEGVDQSAKPMLPLIAINTTAGTASEMT 146
Query: 118 XXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
I EE H K I P++++ DP L P ++ +G D HA+E++ +I
Sbjct: 147 RFCIITDEERHIKMAIVDKHTTPLISVNDPELMLAKPASLTAATGMDALTHAIEAYVSIA 206
Query: 178 FTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAAT 237
T PI+D A ++ +Q + +V N ++EAR M A
Sbjct: 207 AT-------------------PITDAVAIKAIELIQAHLRTAVKNGENLEAREQMAYAQF 247
Query: 238 MAGVGIGNAGVHLCHGLAYPIAG 260
MAG+ NA + H +A+ + G
Sbjct: 248 MAGMAFNNASLGYVHAMAHQLGG 270
>UniRef50_A5D4Z8 Cluster: Alcohol dehydrogenase; n=1; Pelotomaculum
thermopropionicum SI|Rep: Alcohol dehydrogenase -
Pelotomaculum thermopropionicum SI
Length = 387
Score = 88.6 bits (210), Expect = 1e-16
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 24/262 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++DP + V D L G+ +V+ +V +P + A F D VA+G
Sbjct: 40 VSDPGIVGTGLADRVKDLLAGGGVAVEVFSEVEPDPGLETVHKAAAFLGRTRPDCLVALG 99
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K A + Y D + DY A V K K P++A+P
Sbjct: 100 GGSSIDVAKGARVIY-DNGGKISDY--AGVNKVKVK--PSLPLMAVPTTAGTGSEVTVFA 154
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E + K ++ L P A +DPL ++ P ++ SG D HA+E++ +
Sbjct: 155 VLSDWEQNIKITVTSEYLAPEAAFVDPLAMVSAPPGITAASGIDALSHAVEAYVS----- 209
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ ++P+SD A ++ + + ++V N GD+ AR+ L + +AG
Sbjct: 210 --------------RAASPVSDNLALGAVELIGGHLRQAVANGGDLAARTGAALGSLLAG 255
Query: 241 VGIGNAGVHLCHGLAYPIAGNV 262
+ NA + L H + ++G+V
Sbjct: 256 MAFNNAFLGLTHSIGAALSGHV 277
>UniRef50_UPI00015BD369 Cluster: UPI00015BD369 related cluster; n=1;
unknown|Rep: UPI00015BD369 UniRef100 entry - unknown
Length = 391
Score = 88.2 bits (209), Expect = 2e-16
Identities = 66/247 (26%), Positives = 112/247 (45%), Gaps = 22/247 (8%)
Query: 15 VLDSLTRNGI-NYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANL 73
V+ +L N I + +YD++ PTD S A E D + +GGGS++D KA +
Sbjct: 49 VISNLILNNIRDVIIYDEIEPNPTDISVNKGAKIAAENKVDFIMGLGGGSILDAAKAIAI 108
Query: 74 YYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
S+ + +YV P G K++ +P+IAIP + K I
Sbjct: 109 VSSNEGFAW-EYVFYPEGP-KSIPYYTRPVIAIPTTAGTGSEVNKYSVISNPNRKEKLAI 166
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPA 193
+H+ P +A++DP T+++ + ++ +G D F HALES+T N L
Sbjct: 167 AHSLNYPKVAIVDPELTMSMDKDLTATTGMDAFYHALESYT---------NKLNNRL--- 214
Query: 194 YQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHG 253
+ + + +F L+ L+ + N EAR +M A +AG+ I + H
Sbjct: 215 ---AEDLDVIALKFILKWLEIAYEDGTNK----EARENMSYGAMLAGIAIDQKRAGIIHT 267
Query: 254 LAYPIAG 260
+ +PI+G
Sbjct: 268 MEHPISG 274
>UniRef50_O68647 Cluster: Alcohol dehydrogenase; n=7; Bacteria|Rep:
Alcohol dehydrogenase - Pseudomonas putida
Length = 382
Score = 88.2 bits (209), Expect = 2e-16
Identities = 63/238 (26%), Positives = 101/238 (42%), Gaps = 25/238 (10%)
Query: 23 GINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEF 82
G +Y +YD+ + EP +D +EG D + +GGGS +D K ++ D
Sbjct: 57 GRSYGLYDQAQPEPEISLVEDCTRAFREGGHDGLIGLGGGSAIDIAKGV-AAFAGHDGAL 115
Query: 83 LDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPIL 142
D V+ + P+IAIP F + ++ + + L P +
Sbjct: 116 ADLFGV-----DQVSRKGPPLIAIPTTAGTGSEVLTWRSFPTRKRSSRKALVSDYLLPDV 170
Query: 143 ALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISD 202
AL+ P +P VS SG D HA+E++ +I +PI+D
Sbjct: 171 ALVSPGLDAHLPTNVSRASGVDALVHAIEAYLSI-------------------NRSPITD 211
Query: 203 VWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
A ++ + + ++ N D+ AR M A+ M G+ GNAGV H LAYP+ G
Sbjct: 212 AIALGAIKLIARALPKAYANPDDLAAREDMATASLMGGMAFGNAGVGAVHALAYPLGG 269
>UniRef50_O73950 Cluster: Iron containing alcohol dehydrogenase;
n=4; cellular organisms|Rep: Iron containing alcohol
dehydrogenase - Pyrococcus furiosus
Length = 390
Score = 87.8 bits (208), Expect = 3e-16
Identities = 66/246 (26%), Positives = 112/246 (45%), Gaps = 22/246 (8%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V + L + G+ V+DK+ P + A++ N V +GGGS +D+ KA +
Sbjct: 53 VQELLKQAGVESIVFDKIIPNPISTHVDEGAEIARKENVSFVVGLGGGSAIDSAKAIAMT 112
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
+ ++ DYV A VG GK + P++AIP + E K GI
Sbjct: 113 AAS-GGKYWDYVPA-VGGGKKPTGAL-PIVAIPTTHGTGTEADPYAVITNPETKEKQGIG 169
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
++ L P +++DP LT+P+ + Y+ D F H++E+F +
Sbjct: 170 YDVLFPKFSIVDPELMLTLPKDQTVYTSMDAFYHSIEAFLNV------------------ 211
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+NP SDV A ++ + Y + N ++EAR+ + A+T AG+ GV H L
Sbjct: 212 -RANPYSDVLALDSMRRIVTYLPLAYENLRNLEARTQLAWASTEAGITETVTGVVANHAL 270
Query: 255 AYPIAG 260
+ ++G
Sbjct: 271 EHGLSG 276
>UniRef50_Q2SC87 Cluster: Alcohol dehydrogenase, class IV; n=8;
Gammaproteobacteria|Rep: Alcohol dehydrogenase, class IV
- Hahella chejuensis (strain KCTC 2396)
Length = 399
Score = 87.4 bits (207), Expect = 3e-16
Identities = 63/259 (24%), Positives = 109/259 (42%), Gaps = 25/259 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINY-KVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+TD V V+ + + G+ ++D V + + + +E DS +A+
Sbjct: 39 ITDKGVRGAGLSDYVITACSEGGVEMASIFDDVPPDSSTEVVRSIAAVYREQGADSIIAV 98
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGSV+DT KA N+ S+ Y A + K +KP IP
Sbjct: 99 GGGSVIDTAKAINILVSEGGDNLAKYSGAGMLKRP-----LKPFFVIPTTAGTGSEVTSV 153
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ + K L P A+IDP TLT+P ++ + D HA+E++T +
Sbjct: 154 AVIADRKKGVKLPFGSPFLLPNAAIIDPRMTLTLPAHITAATAMDALTHAVEAYTCM--- 210
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
NP+SD +A ++ + ++ + ++N D + R + A+TMA
Sbjct: 211 ----------------AKNPLSDAYAFSAVKKISEHLLEVMDNPKDPQGRLELAQASTMA 254
Query: 240 GVGIGNAGVHLCHGLAYPI 258
G+ N+ V L H L + +
Sbjct: 255 GIAFSNSMVGLVHALGHAL 273
>UniRef50_Q18XS4 Cluster: Iron-containing alcohol dehydrogenase;
n=5; Clostridiales|Rep: Iron-containing alcohol
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 405
Score = 87.0 bits (206), Expect = 4e-16
Identities = 68/260 (26%), Positives = 112/260 (43%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD ++SL + + L L + G+ Y VYDK PT + ++A+ +E + VA G
Sbjct: 52 VTDQGISSLGLVNSFLQDLDKAGVRYTVYDKTVPNPTLDNIEEALKLYQEQQCEGIVAFG 111
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD K ++P ++ G K V ++ P+ AIP
Sbjct: 112 GGSPMDCAKGVGARVANPHKS----ISQMKGVLK-VRRKLPPLFAIPTTAGTGSEATLAA 166
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K ++ AL P A++DPL T+ +P+ +++ +G D HA+E++
Sbjct: 167 VISDPRNREKYPVNDTALIPHYAVLDPLLTVGLPKHITSTTGLDALTHAVEAYIG----- 221
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
R Q + +S R L + + N V+AR +M A+ AG
Sbjct: 222 ----------RSNTQETTELSRKAVRLIFDNLYIAYSQGEN----VKARENMLKASYYAG 267
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
V A V H LA+ + G
Sbjct: 268 VAFTRAYVGYIHALAHALGG 287
>UniRef50_A1VAN7 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Desulfovibrio|Rep: Iron-containing alcohol
dehydrogenase - Desulfovibrio vulgaris subsp. vulgaris
(strain DP4)
Length = 397
Score = 86.6 bits (205), Expect = 6e-16
Identities = 57/227 (25%), Positives = 103/227 (45%), Gaps = 20/227 (8%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
VL L +NG ++++VR P+ + A+ D V +GGGS +D KA L
Sbjct: 51 VLALLRQNGCEPMLFERVRPNPSLVHVDEGACVARANGCDFIVGLGGGSPIDAAKAIALA 110
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
++ + DY+ + G + P++AIP + +E K G
Sbjct: 111 AAN-GGSYWDYIQSGTGGRRTPQHPALPVVAIPTTAGTGTEADPWTVVTRDETQEKIGWG 169
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
+++ P+L+++DP T+TVP +++ +G D F HA+E++ ++
Sbjct: 170 NDSTYPVLSIVDPALTVTVPPRITAMTGMDAFFHAVEAYLSL------------------ 211
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
P SD+ A + L ++ ++V VE RS + A+T AG+
Sbjct: 212 -SRQPSSDLLALEAVSLLAQFLPQAVRQGDSVEVRSMVSWASTAAGL 257
>UniRef50_P10127 Cluster: Alcohol dehydrogenase 4; n=4;
Ascomycota|Rep: Alcohol dehydrogenase 4 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 465
Score = 86.6 bits (205), Expect = 6e-16
Identities = 67/260 (25%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A++ V L +N +YDK + P + + KE N + V+IG
Sbjct: 121 VTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIG 180
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS D KA L ++ E DY K A+ P+ AI
Sbjct: 181 GGSAHDNAKAIALLATN-GGEIGDYEGVNQSKKAAL-----PLFAINTTAGTASEMTRFT 234
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I EE K I N + P +A+ DP +P ++ +G D H +E++ +
Sbjct: 235 IISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVS----- 289
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
SNPI+D A + + + V + + D +AR+ M A +AG
Sbjct: 290 --------------TASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAG 335
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + H LA+ + G
Sbjct: 336 MAFNNASLGYVHALAHQLGG 355
>UniRef50_Q8GAW4 Cluster: 5-hydroxyvalerate dehydrogenase; n=2;
Proteobacteria|Rep: 5-hydroxyvalerate dehydrogenase -
Comamonas sp. (strain NCIMB 9872)
Length = 384
Score = 85.8 bits (203), Expect = 1e-15
Identities = 71/267 (26%), Positives = 112/267 (41%), Gaps = 27/267 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V A +DSL I ++ +V+ +P + A A+E + + G
Sbjct: 37 VTDKGVHQAGLTSAAMDSLKAADIAVTIFSEVQADPPESVIVQAAAAAREAGANGIIGFG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT K L P ++A G G A ++ P+I IP
Sbjct: 97 GGSSMDTAKLVALLVKSPQE-----LSAIYGAGLARGPRL-PLIQIPTTAGTGSEVTPIS 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K +S + L P +AL+D T+ +P V+ +G D HA+E+ +
Sbjct: 151 VVTTPTDEKKPVVS-SLLLPDIALLDAQLTIALPPAVTGATGVDALVHAIEALST----- 204
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
L+ NP+SD+ A +Q + + +V ++E R M LA+ AG
Sbjct: 205 --------RLK-----RNPLSDLLAIKAVQMIYDHLPLAVKEGSNLEVREQMLLASLFAG 251
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKSFVP 267
+ NA V H AYP+ V+ VP
Sbjct: 252 MAFSNASVGAVHAFAYPL--GVRFHVP 276
>UniRef50_A3XYH0 Cluster: Alcohol dehydrogenase, iron-containing;
n=2; Vibrio|Rep: Alcohol dehydrogenase, iron-containing
- Vibrio sp. MED222
Length = 386
Score = 85.8 bits (203), Expect = 1e-15
Identities = 72/252 (28%), Positives = 107/252 (42%), Gaps = 23/252 (9%)
Query: 19 LTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYS 76
L+ GI +D V P + A N D +AIGGGS +DT K +A +
Sbjct: 55 LSEQGIEVTHFDGVVPNPPTTVVELGRQVAIGNNCDVVLAIGGGSSIDTAKIISATINTE 114
Query: 77 DPD-AEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
D A + ++P G + +V P+IA+P + E HAK + H
Sbjct: 115 SLDWAHWFATYDSPFGDVNPLPAKVVPLIAVPTTSGTGSQMTQAAVITDLEQHAKLTLFH 174
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
P ALIDP LT+P +++ +GFD F HA ESFT G P
Sbjct: 175 PEFFPCEALIDPELMLTLPPRMTAMTGFDAFSHAFESFT-------GTRP---------- 217
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
+P D A ++ + + V+N D+ R + A T+ G+ + N G H L
Sbjct: 218 --SPFVDGMALEAMKLVIDHLPSVVDNGADLHGRCQLAKADTLGGISLANGGAGAPHPLG 275
Query: 256 YPIAGNVKSFVP 267
I G+ K+ +P
Sbjct: 276 -EILGSSKTNLP 286
>UniRef50_Q4KCL4 Cluster: Alcohol dehydrogenase, iron-containing;
n=6; Pseudomonas|Rep: Alcohol dehydrogenase,
iron-containing - Pseudomonas fluorescens (strain Pf-5 /
ATCC BAA-477)
Length = 398
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/262 (24%), Positives = 113/262 (43%), Gaps = 24/262 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + L P + L ++ + V+ ++ P+ + + + G DS +A+G
Sbjct: 39 VTDPGMLELEPFGLLTAHLEQSRQGFAVFAELASNPSLDDVQRGVQAFRAGGHDSLIALG 98
Query: 61 GGSVMDTCKAANLYYSDPDA----EFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
GGS MD K L DP E+ + + + P+IA+P
Sbjct: 99 GGSAMDAAKGIALAAVDPQGLQRFEWSQVIEHYPSLSDFPRLGLPPLIALPTTAGTGSEL 158
Query: 117 XXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
+ + K ISH L P ++DPL T +P ++ +G D H +E+F +
Sbjct: 159 GREAVLTDSQQQVKRVISHPELLPACVILDPLLTRGLPPALTAATGMDALTHHIEAFCS- 217
Query: 177 PFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAA 236
P Y +P+S A ++ +Q++ R+V++ D++AR M +A+
Sbjct: 218 ---------------PLY---HPMSSAIAVEGMRLVQQHLRRAVSHGQDLDAREGMLVAS 259
Query: 237 TMAGVGIGNAGVHLCHGLAYPI 258
MA V G+ H LA+P+
Sbjct: 260 AMAAVAF-QKGLGGVHALAHPL 280
>UniRef50_Q93CV7 Cluster: Putative methanol dehydrogenase; n=2;
Lactobacillus sakei|Rep: Putative methanol dehydrogenase
- Lactobacillus sakei
Length = 383
Score = 85.4 bits (202), Expect = 1e-15
Identities = 66/257 (25%), Positives = 113/257 (43%), Gaps = 27/257 (10%)
Query: 3 DPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGG 62
D + ++ +K + LT N I + +YDKV +P + F K + DS +AIGGG
Sbjct: 38 DSFLKEVAIVKRLQVKLTENNIQFSIYDKVVSDPPTTVVDEGAEFFKAQDCDSLIAIGGG 97
Query: 63 SVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKP-MIAIPXXXXXXXXXXXXXI 121
S +D + N+ + + +YV A + I+ P +IA+P I
Sbjct: 98 SAIDVARGINIVRIN-GGKISEYVTA------SNEIKDCPGLIAVPTTSGTGSELSNALI 150
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
E K + N A+++P +T+P+ ++ +G D F HA E +T+
Sbjct: 151 VTDTENQTKLAVLANNAVSEFAVLNPELVMTLPKGMTIATGLDAFSHAAEGYTSTL---- 206
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
++P++D + L KY + + + D EAR + +AAT+ G
Sbjct: 207 ---------------ASPVTDAICEKIMYLLVKYLPKVIEDGQDREARERVMVAATLGGW 251
Query: 242 GIGNAGVHLCHGLAYPI 258
+ NAG H H +A+ I
Sbjct: 252 MLNNAGTHAGHSVAHVI 268
>UniRef50_O28260 Cluster: Alcohol dehydrogenase, iron-containing;
n=1; Archaeoglobus fulgidus|Rep: Alcohol dehydrogenase,
iron-containing - Archaeoglobus fulgidus
Length = 371
Score = 85.4 bits (202), Expect = 1e-15
Identities = 63/232 (27%), Positives = 105/232 (45%), Gaps = 29/232 (12%)
Query: 25 NYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLD 84
+Y+++ V EP G D I ++ +FD+ V +GGGS +D K + + A+ ++
Sbjct: 45 DYEIFSDVEPEPEIGIVDDII---EKFSFDTVVGVGGGSTLDVAKLTAVAAGEK-AKAVE 100
Query: 85 YVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILAL 144
V GK + + ++ P +F + K +L +A+
Sbjct: 101 LV------GKKLPERKCKLLLCPTTAGTGSEVTKLAVFKIPKREVKYVFDDESLYADIAI 154
Query: 145 IDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVW 204
IDP TL+ P V+ SG D FCHA+E++T++ SNPISD++
Sbjct: 155 IDPKLTLSCPPHVTASSGIDAFCHAIEAYTSL-------------------FSNPISDMF 195
Query: 205 ARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAY 256
A + + K + N +V AR+ M A+ +AG+ +AG L H L Y
Sbjct: 196 AEKAIAIIPKALREAYANGENVRARTDMSFASLLAGIAFNSAGTGLGHALGY 247
>UniRef50_Q98H17 Cluster: Dehydrogenase; iron-containing alcohol
dehydrogenase; 4- hydroxybutyrate dehydrogenase;
methanol dehydrogenase; n=15; Proteobacteria|Rep:
Dehydrogenase; iron-containing alcohol dehydrogenase; 4-
hydroxybutyrate dehydrogenase; methanol dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 390
Score = 84.6 bits (200), Expect = 2e-15
Identities = 67/258 (25%), Positives = 107/258 (41%), Gaps = 21/258 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A L + + L L + Y V+ +V+ P D + I K+G D +A G
Sbjct: 39 VTDPGLAKLPVVASTLKILDDAKVPYGVFSEVKPNPVDSNLTAGIAVFKKGKHDGVIAFG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + + D+ + +A + + P+IA+P
Sbjct: 99 GGSALDLGKLI-AFQAGQTRPVWDFEDVGDWWTRANSDAIAPIIAVPTTAGTGSEVGRAG 157
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ EE H K I H L P + + DP ++ +P ++ +G D H LE++ A
Sbjct: 158 VITNEETHTKKVIFHPKLLPAIVIADPELSVGMPAFITAGTGMDALAHCLEAYCA----- 212
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P P G I+ R + L K + N D+ AR+ M AA M G
Sbjct: 213 -------PGYHPMADG---IAVEGIRLVFENLPKAYA----NGKDLVARAHMMSAAAM-G 257
Query: 241 VGIGNAGVHLCHGLAYPI 258
G+ H L++PI
Sbjct: 258 AAAFQKGLGAIHSLSHPI 275
>UniRef50_Q67M75 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Symbiobacterium thermophilum
Length = 322
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/210 (28%), Positives = 93/210 (44%), Gaps = 25/210 (11%)
Query: 54 DSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXX 113
D VA+GGGS +D KA + ++ + DY V P+IA+P
Sbjct: 28 DLVVAVGGGSAIDVAKATAVLAANGGTAY-DYFGVD-----RVPRPGLPVIAMPTTAGTG 81
Query: 114 XXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
IF K GI + P +A++DP TLT P V+ +G D HA+ESF
Sbjct: 82 AEATPNAIFTNTRTQVKEGIVSPYMMPAVAIVDPELTLTAPPGVTAATGMDALTHAVESF 141
Query: 174 TAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMH 233
T++ + P +D++A ++ + + +V GD+ AR+ M
Sbjct: 142 TSVK-------------------AAPTTDLFAAEAIRRIGRSIRTAVFRGGDLAARTDMA 182
Query: 234 LAATMAGVGIGNAGVHLCHGLAYPIAGNVK 263
L + AG+ I NAG H +AYP+ G +
Sbjct: 183 LGSLYAGIAICNAGTGAVHAMAYPLGGQFR 212
>UniRef50_Q3ZWC0 Cluster: Alcohol dehydrogenase, iron-containing;
n=3; Dehalococcoides|Rep: Alcohol dehydrogenase,
iron-containing - Dehalococcoides sp. (strain CBDB1)
Length = 380
Score = 84.6 bits (200), Expect = 2e-15
Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 33/262 (12%)
Query: 6 VASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVM 65
V L ++ L L + ++D V P + + I A+ D +A+GGGS M
Sbjct: 41 VRRLGILERALFLLKEACVQTTLFDHVEPNPRSSTVDEGIKLARAKGVDMIIALGGGSAM 100
Query: 66 DTCKAA--NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFD 123
D KA L + P +++ P G + P+I IP +
Sbjct: 101 DAAKAIAFGLACNGPVWDYIQQEEYPEG-------DLLPLIMIPTVAASGSEANGNAVIS 153
Query: 124 YEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGP 183
E H K IS N L+P ++L+DPL TL++P + + G DIFCH
Sbjct: 154 NWEKHEKRVISDNRLQPKVSLVDPLLTLSLPPRQTAQGGVDIFCHI-------------- 199
Query: 184 APANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA---- 239
A P L A ++P+ D A ++ + +Y ++V D+++R+ + +T+A
Sbjct: 200 --AEPYLTAA--DTSPLRDGMAELAMRLVVEYLPKAVQTPHDLQSRTQLSWLSTIACSQF 255
Query: 240 -GVGIGNAGVHLCHGLAYPIAG 260
+G G +G HGL + ++G
Sbjct: 256 MSLG-GKSGNMTMHGLEHALSG 276
>UniRef50_A6VQQ6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Actinobacillus succinogenes 130Z|Rep:
Iron-containing alcohol dehydrogenase - Actinobacillus
succinogenes 130Z
Length = 385
Score = 84.6 bits (200), Expect = 2e-15
Identities = 64/260 (24%), Positives = 104/260 (40%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP V + + L GIN +V EP AK N + IG
Sbjct: 37 ITDPGVFAAGLINEPKTILENAGINVQVISDTPPEPPLAQVNQIYQHAKNTNAHMVIGIG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT K + ++ D E D V+ GK K N + P + +P
Sbjct: 97 GGSAMDTAKLVAILLNN-DVELQDVVD---GKAKFKNRGI-PTVMVPTTSGTGSEATPNS 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E K GI + P ++DP T+ +P ++ +G D CHA+E + +
Sbjct: 152 IVLIPERELKVGIVDEKMLPNCVILDPQMTIGLPPHITANTGIDALCHAVECYIS----- 206
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ ++P SD +A ++ + + + + +++AR M L + G
Sbjct: 207 --------------KKASPFSDTFALKAVELIGRSIRTAYKDGKNLQAREDMLLGSYFGG 252
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
I + H L+YP+ G
Sbjct: 253 ASIATSSTVAIHALSYPLGG 272
>UniRef50_Q24803 Cluster: Aldehyde-alcohol dehydrogenase 2
[Includes: Alcohol dehydrogenase (EC 1.1.1.1) (ADH);
Acetaldehyde dehydrogenase (EC 1.2.1.10) (ACDH)]; n=65;
cellular organisms|Rep: Aldehyde-alcohol dehydrogenase 2
[Includes: Alcohol dehydrogenase (EC 1.1.1.1) (ADH);
Acetaldehyde dehydrogenase (EC 1.2.1.10) (ACDH)] -
Entamoeba histolytica
Length = 870
Score = 84.6 bits (200), Expect = 2e-15
Identities = 64/265 (24%), Positives = 123/265 (46%), Gaps = 28/265 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTR--NGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
++D + L + V+D L R N + +++ V +P+ + + + D+ +A
Sbjct: 493 VSDRMMYKLGYVDRVMDVLKRRSNEVEIEIFIDVEPDPSIQTVQKGLAVMNTFGPDNIIA 552
Query: 59 IGGGSVMDTCKAANLYYSDPDAEFL----DYVNAPVGKGKAVNIQVKP-MIAIPXXXXXX 113
IGGGS MD K L Y P+A+F +++ K + K +I IP
Sbjct: 553 IGGGSAMDAAKIMWLLYEHPEADFFAMKQKFIDLRKRAFKFPTMGKKARLICIPTTSGTG 612
Query: 114 XXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
+ E K ++ +L P +A++DP+ T+++P++ +G D+ HA E++
Sbjct: 613 SEVTPFAVISDHETGKKYPLADYSLTPSVAIVDPMFTMSLPKRAIADTGLDVLVHATEAY 672
Query: 174 TAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMH 233
++ +N +D AR ++ + + ++S N GD+EAR MH
Sbjct: 673 VSVM-------------------ANEYTDGLAREAVKLVFENLLKSYN--GDLEAREKMH 711
Query: 234 LAATMAGVGIGNAGVHLCHGLAYPI 258
AAT+AG+ +A + + H +A+ +
Sbjct: 712 NAATIAGMAFASAFLGMDHSMAHKV 736
>UniRef50_A5UV11 Cluster: Iron-containing alcohol dehydrogenase;
n=5; Chloroflexi (class)|Rep: Iron-containing alcohol
dehydrogenase - Roseiflexus sp. RS-1
Length = 388
Score = 84.2 bits (199), Expect = 3e-15
Identities = 63/262 (24%), Positives = 112/262 (42%), Gaps = 25/262 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+ DP V + V + L + + V + + + + A++ D +A+G
Sbjct: 38 VADPGVVQAGLLDRVREGLEGSITVAGAFTDVPPDSSVATVEQGAAVARDAGADVLIAVG 97
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA + ++ + DY A + + + PMIAIP
Sbjct: 98 GGSAIDTAKAMRILLTEGGTLY-DYQGANL-----LTRPLFPMIAIPTTAGTGSEVTPVA 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E+ K L P LA++DP T T+P +++ +G D HA+E+F +
Sbjct: 152 VIRDEQAEQKLFFLSPYLGPELAILDPEMTRTLPPRLTAATGMDALSHAIETFVGV---- 207
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G+NPI+D A + + Y + +N D+EAR +M +AA +AG
Sbjct: 208 ---------------GANPITDSLAIQAIDMISNYLRAATHNGEDMEARGNMLIAAAIAG 252
Query: 241 VGIGNAGVHLCHGLAYPIAGNV 262
+ G+ + G+ + + V
Sbjct: 253 IAFSTTGIGVNTGIIHAASHTV 274
>UniRef50_Q39NZ6 Cluster: Iron-containing alcohol dehydrogenase;
n=21; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 388
Score = 83.8 bits (198), Expect = 4e-15
Identities = 70/257 (27%), Positives = 102/257 (39%), Gaps = 28/257 (10%)
Query: 5 NVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSV 64
N L P KA SL G V+D+V +P + + FA+ D + +GGGS
Sbjct: 49 NAGVLEPAKA---SLAAEGFRVAVFDEVVADPPESVVSRCVEFARGAEADIVIGLGGGSS 105
Query: 65 MDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDY 124
MD K A + + Y +G K + P++ IP I
Sbjct: 106 MDIAKLAAVLTVSRQSLAEMY---GIGNVKGARL---PLVQIPTTAGTGSEVTNISIVSV 159
Query: 125 EEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPA 184
E K GI L ++D T+ +P + +G D HA+E++T
Sbjct: 160 NET-TKMGIVSRQLYADKVILDAELTVGLPRSHTAATGIDAMVHAIEAYT---------- 208
Query: 185 PANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIG 244
+ N +SD AR L+ L + + N D AR +M L AT+AG
Sbjct: 209 --------SKHKKNALSDALAREALRLLVSNLIPACENGHDRHAREAMLLGATLAGQAFA 260
Query: 245 NAGVHLCHGLAYPIAGN 261
NA V H LAYP+ G+
Sbjct: 261 NAPVAAVHALAYPLGGH 277
>UniRef50_Q0EUX2 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Clostridia|Rep: Iron-containing alcohol
dehydrogenase - Thermoanaerobacter ethanolicus X514
Length = 384
Score = 83.8 bits (198), Expect = 4e-15
Identities = 66/258 (25%), Positives = 114/258 (44%), Gaps = 29/258 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D V++L + SL+ GI++ +D++ +P D A+E D VA+G
Sbjct: 39 VSDKTVSNLDIYQKCKKSLSDAGISFVEFDEILPDPPDYIVNKGGEVAREQKVDGIVAVG 98
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSVMD K N+ ++P Y P K P++ +
Sbjct: 99 GGSVMDAAKGINILINNP-PPINRYFGNPFFKPGV------PVVMVVTTAGTGSESTGVA 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ +AK + A L ++DP T+++P+ + ++G D F HA E+ TA
Sbjct: 152 VITDTVNNAKNSVFGVA---SLGILDPEATVSLPKDATVHTGMDAFAHAAEAITA----- 203
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ NP S + A + + KY + + ++EAR++M LA+ AG
Sbjct: 204 --------------KLPNPKSQLLAFDAINKIIKYLPVAAEDGANIEARANMLLASNFAG 249
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ +A VHL H +A+ I
Sbjct: 250 IAFNDALVHLGHAIAHTI 267
>UniRef50_Q1GWE1 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 388
Score = 83.4 bits (197), Expect = 6e-15
Identities = 70/261 (26%), Positives = 108/261 (41%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + + + + L GI +V+ +PT S + F +EG+ D V G
Sbjct: 37 VTDPWLLNSGRVDELAGGLASAGIAARVFADTVPDPTIASINVGVAFLQEGDHDCVVGFG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D+ KA L A DY AP + P+IAIP
Sbjct: 97 GGSPLDSAKAIALLGHHGGA-MADY-KAP----HVQDTPGLPVIAIPTTAGTGSEATRFT 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I + K A P+ AL+D T T P +++ +G D HA+E++ +
Sbjct: 151 IITDDATDEKMLCPGLAYLPVAALVDYELTFTKPRRLTADTGIDSLTHAIEAYVS----- 205
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +NP SD A ++ + R + D AR +M L AT AG
Sbjct: 206 --------------RRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAAREAMMLGATQAG 251
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
+ N+ V L HG++ PI +
Sbjct: 252 IAFSNSSVALVHGMSRPIGAH 272
>UniRef50_A0UW83 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Clostridium cellulolyticum H10|Rep: Iron-containing
alcohol dehydrogenase - Clostridium cellulolyticum H10
Length = 383
Score = 83.4 bits (197), Expect = 6e-15
Identities = 58/247 (23%), Positives = 106/247 (42%), Gaps = 21/247 (8%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
++ +D L GI V++ V +P + K+ D + +GGGS MD KA
Sbjct: 47 LQKTIDYLKEAGIESNVFEGVEPDPLFSTVYRGAEVMKQFQPDIIIGLGGGSAMDAAKAM 106
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
+YY P L+ + P K N + ++ IP + +E H K
Sbjct: 107 WVYYEHPGLTTLNDIVPPNVIPKLRNKAI--LVCIPSTSGTASEVSRSVVITDDETHIKY 164
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
G+ + + P +A+ DP T+T+P K++ +G D HALE+
Sbjct: 165 GVGNMEMMPDIAICDPEVTVTMPAKITAETGMDALTHALEAL------------------ 206
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLC 251
A +N IS+++A+ + + ++ + D+ +R M A+ AG+ N + +
Sbjct: 207 -ASNRANYISNIFAKNAAKDIIVNLPKAYSQGNDIGSREIMINASMAAGMAFTNVSLGIV 265
Query: 252 HGLAYPI 258
H +A+ +
Sbjct: 266 HSMAHTL 272
>UniRef50_Q6D0N6 Cluster: Putative alcohol dehydrogenase; n=6;
Enterobacteriaceae|Rep: Putative alcohol dehydrogenase -
Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 378
Score = 83.0 bits (196), Expect = 7e-15
Identities = 62/260 (23%), Positives = 110/260 (42%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD N+ L ++A++ + + + D V EP+ + + D + +G
Sbjct: 30 VTDKNIVGLPDVQALIAQVKQAVPQVLLVDNVPAEPSQHDVAHILSQLTQTQTDLVIGVG 89
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D K ++ + + LD + A G+ + ++ IP
Sbjct: 90 GGSVLDVAKLLSVLCAGDETVTLDNLLA----GEKPTRRTTSLL-IPTTAGTGSEATPNA 144
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E K GI + P + P T+++P ++ +G D CH +E FT+
Sbjct: 145 ILAIPEKETKVGIITPVMLPDYVALVPELTISMPPHIAASTGIDALCHLIECFTSTI--- 201
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+NP+SD +A L+ L SV G++EA+ +M A+ G
Sbjct: 202 ----------------ANPVSDNYALIGLKKLFANLETSVREPGNLEAKLNMLWASYYGG 245
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
I ++G HL H ++YP+ G
Sbjct: 246 AAIAHSGTHLVHAMSYPLGG 265
>UniRef50_Q9APW5 Cluster: 1,3-propanediol dehydrogenase; n=4;
Pseudomonas|Rep: 1,3-propanediol dehydrogenase -
Pseudomonas aeruginosa
Length = 415
Score = 83.0 bits (196), Expect = 7e-15
Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + + V SL I + V+ P A + +AIG
Sbjct: 66 VTDAGVKAAGLLNGVYASLNEWEIAFDEISDVKANPRSEDINQAAQLYRGKGIHGLLAIG 125
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD KA +L + + DY + + + P++AIP
Sbjct: 126 GGSAMDAAKAISLLLTH-EGRIEDYEGS-----FTLRHAIPPIVAIPTTAGTGSEVTCFS 179
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ H K + + P+LAL+D T+P ++ +G D HA+E++T
Sbjct: 180 VITDTARHFKMSVQDYRVGPVLALLDSRILDTLPASIAAATGMDALTHAIEAYTC----- 234
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ SNPISD A ++ + +Y +V G++ AR M +A+ +AG
Sbjct: 235 --------------RVSNPISDGLALHAIRLISQYLRPAVLEPGNLHAREQMLVASLIAG 280
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ GNA V H ++ I G
Sbjct: 281 MAFGNADVGSVHCISEAIGG 300
>UniRef50_A6M1I4 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Clostridium|Rep: Iron-containing alcohol
dehydrogenase - Clostridium beijerinckii NCIMB 8052
Length = 376
Score = 82.6 bits (195), Expect = 1e-14
Identities = 57/245 (23%), Positives = 111/245 (45%), Gaps = 25/245 (10%)
Query: 16 LDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYY 75
+D L + Y+++DKV P + + + KE D + +GGGS+MD K+
Sbjct: 51 IDLLNEAKVQYEIFDKVEQNPLTTTVYEGVDVIKETGCDVVLGLGGGSIMDAAKSIAFSA 110
Query: 76 SDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
+P + +Y+ + +G + P++ +P + E K +
Sbjct: 111 KNP-GDISEYIFG-IKQGS----EALPIVLVPTTCGTGSEGNCFSVLTNPETKDKKSLRT 164
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
N + ++IDP +T+ + + + GFD H +E++ + +
Sbjct: 165 NIIIAKASIIDPELMVTMSKSILSSVGFDALAHNMEAYLS-------------------K 205
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
P++D+ A + ++ L + V+ N+ D++A S+ LA+T+ G+ IG AGV HGL
Sbjct: 206 IGQPLTDMKAFYGIKLLSENLVKVYNDPSDLDAWDSVTLASTLGGMVIGIAGVTAPHGLE 265
Query: 256 YPIAG 260
+P +G
Sbjct: 266 HPASG 270
>UniRef50_Q8G420 Cluster: Adh2; n=60; cellular organisms|Rep: Adh2 -
Bifidobacterium longum
Length = 909
Score = 82.2 bits (194), Expect = 1e-14
Identities = 69/267 (25%), Positives = 118/267 (44%), Gaps = 30/267 (11%)
Query: 3 DPNVASLSPMKAVLDSLTR--NGINYKVYDKVRVEPTDGSF-KDAIHFAKEGNFDSFVAI 59
D + L + ++D L N + +++ D V EP+ + K A +E D+ +A+
Sbjct: 503 DKVMEQLGIVDKIIDQLRARSNRVTFRIIDYVEPEPSVETVEKGAEMMREEFEPDTIIAV 562
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVG-KGKAVNI----QVKPMIAIPXXXXXXX 114
GGGS MD K L Y P+ F D + +A I + ++ IP
Sbjct: 563 GGGSPMDASKIMWLLYEHPEIAFSDVREKFFDIRKRAFKIPPLGKKAKLVCIPTSSGTGS 622
Query: 115 XXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFT 174
+ + K I+ AL P +A++DP+ T P K+++ +GFD H++E++
Sbjct: 623 EVTPFAVITDHKTGYKYPITDYALTPSVAIVDPVLARTQPRKLASDAGFDALTHSMEAYV 682
Query: 175 AIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDV---EARSS 231
++ Y +N +D A + + SVN + A+
Sbjct: 683 SV-----------------Y--ANDFTDGMALHAAKLIWDNLAESVNGEPGLVKTNAQEK 723
Query: 232 MHLAATMAGVGIGNAGVHLCHGLAYPI 258
MH AATMAG+ G+A + +CHG+A+ I
Sbjct: 724 MHNAATMAGMAFGSAFLGMCHGMAHTI 750
>UniRef50_Q7UK80 Cluster: Putative iron alcohol dehydrogenase; n=2;
Planctomycetaceae|Rep: Putative iron alcohol
dehydrogenase - Rhodopirellula baltica
Length = 386
Score = 82.2 bits (194), Expect = 1e-14
Identities = 66/256 (25%), Positives = 100/256 (39%), Gaps = 25/256 (9%)
Query: 3 DPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGG 62
DP + + + L + + PT + A + D + +GGG
Sbjct: 45 DPGIVAAGHFDRITGLLRDKNWEVHAFHEFAENPTSAMVDAGVSVAADFQPDLLIGLGGG 104
Query: 63 SVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIF 122
S MD K N YS DY G GKA + ++ PMIAIP +
Sbjct: 105 SSMDCAKGINFVYSC-GGRIHDYH----GVGKATS-EMLPMIAIPTTAGTGSEAQSFALI 158
Query: 123 DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERG 182
E H K +AL+DP TLT P V+ +G D HA+E++ +
Sbjct: 159 SDAETHVKMACGDPKAACRIALLDPTFTLTQPRGVTALTGIDAISHAVETYVS------- 211
Query: 183 PAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVG 242
+ N +S ++R L + FVR + D+EAR+ M L A +AG+
Sbjct: 212 ------------KKRNVMSTTYSRRAFGLLGRSFVRVLQVPDDLEARADMQLGACLAGMA 259
Query: 243 IGNAGVHLCHGLAYPI 258
I + + H A P+
Sbjct: 260 IETSMLGAAHATANPL 275
>UniRef50_A5NN36 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Methylobacterium sp. 4-46|Rep: Iron-containing
alcohol dehydrogenase - Methylobacterium sp. 4-46
Length = 438
Score = 82.2 bits (194), Expect = 1e-14
Identities = 67/260 (25%), Positives = 113/260 (43%), Gaps = 27/260 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + LD L G + +V+ V +P+ + + D V +G
Sbjct: 89 VTDPGLVKAGIAGRALDLL--QGRDVEVFSDVEPDPSIETVVACADRVRTQKCDLIVGLG 146
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT K A++ ++P A DY+ G K + V P I +P
Sbjct: 147 GGSAIDTAKCASVMATNPGA-VEDYL----GIDKVTSPGV-PKIIVPTTAGTGSEVTNVA 200
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + H K GI L AL+DP TL +P V+ +G D HA+E++ +
Sbjct: 201 VLSLKAQHTKKGIVSRYLLADTALLDPELTLGLPAAVTAATGMDALTHAIEAYVS----- 255
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ + P++D +A ++ + + +V+N ++ AR +M A+ AG
Sbjct: 256 --------------RFAQPMTDDFALRAIRLIGENLRTAVHNGQNIRAREAMLTASLYAG 301
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
G+A + HGLA P+ G
Sbjct: 302 YAFGSAATGMVHGLAMPLGG 321
>UniRef50_Q1M843 Cluster: Putative alcohol dehydrogenase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
alcohol dehydrogenase - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 390
Score = 81.8 bits (193), Expect = 2e-14
Identities = 72/258 (27%), Positives = 107/258 (41%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + + ++ GI V+D V V+ + A +E D+ VAIG
Sbjct: 36 VTDEKVRAAGLTRNAEAAIAEAGIALTVFDGVVVDAPSHVIEAAAEICRECGVDAVVAIG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+DT K PD LD + G G+A ++ P++ +P
Sbjct: 96 GGSVLDTAKLVAYLAKTPDK--LDDI---YGIGRATGDRL-PLLLVPTTAGTGSEVTPIS 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I K IS L P ++DP+ TL +P ++ +G D HA+E++T
Sbjct: 150 IVKTPNDEKKAVISPR-LIPDWVILDPVLTLGLPPHLTAQTGIDAMAHAIEAYT------ 202
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G NP SD A L L + + D+EAR M + +AG
Sbjct: 203 -GKIK-----------KNPTSDQLALKALALLSANLRKVYTDGSDLEARLDMLFGSMLAG 250
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ N+ V H LAYPI
Sbjct: 251 MAFANSPVAAVHALAYPI 268
>UniRef50_A6X351 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Iron-containing alcohol dehydrogenase - Ochrobactrum
anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 402
Score = 81.4 bits (192), Expect = 2e-14
Identities = 71/262 (27%), Positives = 107/262 (40%), Gaps = 27/262 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + L SL + G V+D V +P + + AK D + +G
Sbjct: 56 VTDKGLHKAGVLDHALASLEKAGFGISVFDDVVADPPESVLFACVEQAKTAGCDIVLGLG 115
Query: 61 GGSVMDTCK-AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS MD K AA L S+ + L G GK ++ P+I IP
Sbjct: 116 GGSSMDIAKLAAVLLVSEQELSEL------YGIGKVQGSRL-PLIQIPTTAGTGSEVTNI 168
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
I E K G+ L ++D T +P + +G D HA+E++T+
Sbjct: 169 TILTTGET-TKMGVVARQLYADFVILDAELTCGLPALHTAATGIDAMVHAIEAYTS---- 223
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
++ NP+SD +AR L+ L + + N D AR +M L A A
Sbjct: 224 ---------RIK-----KNPLSDAFAREALKLLSANLIAACENGNDRHAREAMLLGANYA 269
Query: 240 GVGIGNAGVHLCHGLAYPIAGN 261
G N+ V H LAYP+ G+
Sbjct: 270 GQAFSNSPVGAVHALAYPLGGH 291
>UniRef50_A1RYX6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Thermofilum pendens Hrk 5|Rep: Iron-containing
alcohol dehydrogenase - Thermofilum pendens (strain Hrk
5)
Length = 377
Score = 81.4 bits (192), Expect = 2e-14
Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 27/244 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
+ L G+ + +V PT + A++ D FVA GGGSV+D KAAN+
Sbjct: 54 IKSQLESAGVEVYFFSEVEPNPTIETADRCAEAARKAGVDFFVAFGGGSVIDVAKAANVV 113
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
YS DY+ + V +++P++A+P + E K +S
Sbjct: 114 YS-LGGSAKDYLWP-----RNVEEKLRPLVAVPTTHGTGSEVTKYSVLVDRETGMKVAVS 167
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
+ L P LA++DPL +P S +G D HA+E+F F+ R
Sbjct: 168 GSGLLPTLAVLDPLVLKHLPSDQSASTGLDALSHAIEAF----FSSR------------- 210
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+ P +D++A + + +V G ++ R M A+ +AG I G ++ HGL
Sbjct: 211 --ATPFTDMFALEASRIAFRKLPCAV--EGFLDCREWMLYASMLAGYAINYTGTNIGHGL 266
Query: 255 AYPI 258
YP+
Sbjct: 267 GYPL 270
>UniRef50_Q184U3 Cluster: Alcohol dehydrogenase; n=2; Clostridium
difficile|Rep: Alcohol dehydrogenase - Clostridium
difficile (strain 630)
Length = 383
Score = 81.0 bits (191), Expect = 3e-14
Identities = 68/265 (25%), Positives = 112/265 (42%), Gaps = 27/265 (10%)
Query: 1 MTDPNVASLSPM-KAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+T PNV L + K V +L GI +D+V PT + AK+ + D +A+
Sbjct: 34 VTTPNVEPLDKLYKRVTLNLIEKGIEVVHFDRVEPNPTVELVNEGFELAKKESVDVVLAV 93
Query: 60 GGGSVMDTCKAANLYYS----DPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXX 115
GGGS +DT K L + D D F Y N P V+ + P+IA+
Sbjct: 94 GGGSSIDTAKVLALTFGLEKIDWDYMFSTYTN-PFKIYDKVSEKELPLIAVSTTSGTGSQ 152
Query: 116 XXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
+ K I H ++DP LT+PE+++ + FD F HA ES+
Sbjct: 153 VTQAAVISRGS--EKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESY-- 208
Query: 176 IPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLA 235
NP +N +++ + ++ + Y + + + ++E R+ + +A
Sbjct: 209 ----------INP-------NANDFTEIMSEKSMELVINYLPKVMEDKNNIEYRTKLAVA 251
Query: 236 ATMAGVGIGNAGVHLCHGLAYPIAG 260
T+ G + NAG H L+ I G
Sbjct: 252 DTLGGSSLANAGAAAPHPLSEIIGG 276
>UniRef50_A6FDL7 Cluster: Possible iron-containing alcohol
dehydrogenase; n=2; Gammaproteobacteria|Rep: Possible
iron-containing alcohol dehydrogenase - Moritella sp.
PE36
Length = 396
Score = 80.6 bits (190), Expect = 4e-14
Identities = 72/261 (27%), Positives = 114/261 (43%), Gaps = 27/261 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L K + D+L I Y ++D+V +PT + K+ DS +A+G
Sbjct: 49 VTDAMLVKLGIAKQLTDALDAENIAYALFDEVTPDPTLSLIGNGWQQYKQYGCDSVIALG 108
Query: 61 GGSVMDTCKA-ANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS MD KA A + DA L VG + V + P IAIP
Sbjct: 109 GGSPMDCAKAIAASAVKNVDARKL------VGMLR-VRKALPPFIAIPTTAGTGSEATVV 161
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ + K I +L P +A++DPL L +P K++ +G D HA+ES+ T
Sbjct: 162 AVVTDPDKKKKFTIVDPSLVPAVAILDPLLMLGLPAKITAETGIDALTHAVESYIGFHAT 221
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
E+ A G + + ++A L T + + ++EAR M +A+ A
Sbjct: 222 EQTKA----------YGYDAVKRIFAN--LPT-------AYADGSNIEARRQMSIASFNA 262
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
GV A + H +A+ + G
Sbjct: 263 GVAFTRASIGYAHAIAHQMGG 283
>UniRef50_A1RUX3 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Pyrobaculum islandicum DSM 4184|Rep:
Iron-containing alcohol dehydrogenase - Pyrobaculum
islandicum (strain DSM 4184 / JCM 9189)
Length = 384
Score = 80.6 bits (190), Expect = 4e-14
Identities = 67/253 (26%), Positives = 114/253 (45%), Gaps = 30/253 (11%)
Query: 8 SLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDT 67
+L ++ VL L G+ Y +++KV P ++ E D+ +AIGGGS +D
Sbjct: 48 ALDDVERVLKEL---GVKYVLFNKVSPNPWASQAEELAKVVWEEGADAVIAIGGGSPIDV 104
Query: 68 CKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEI 127
K A + ++ + DYV V K K ++ P+IA+ + ++
Sbjct: 105 SKIATIIVAN-GGKVYDYVRG-VKKAK----RMIPLIAVNLTHGTGTEVDKWAVVTLDDT 158
Query: 128 HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPAN 187
K GI+ A P L++ DP +TLT+ E+ + Y+ D F H+ ES TA
Sbjct: 159 REKIGIA--ARYPDLSIDDPTYTLTLDERQTIYTSLDAFYHSYESATA------------ 204
Query: 188 PALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAG 247
+ SNP+S A + T+ + + N D+ R M A+ +AG+ I A
Sbjct: 205 -------KTSNPLSQSLAESAIGTIAETLPKLAENLRDLALRYRMLYASMIAGIAIDMAR 257
Query: 248 VHLCHGLAYPIAG 260
H+ H + + ++G
Sbjct: 258 THIIHAIEHVLSG 270
>UniRef50_Q8G3T1 Cluster: Possible lactaldehyde reductase; n=8;
Bacteria|Rep: Possible lactaldehyde reductase -
Bifidobacterium longum
Length = 383
Score = 80.2 bits (189), Expect = 5e-14
Identities = 64/263 (24%), Positives = 111/263 (42%), Gaps = 27/263 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + + V L G+ Y+V+ V+ P KD + E D + +G
Sbjct: 36 VTDPVLLETGTAEKVTKVLDEAGLPYEVFSNVKPNPPVECIKDGVAKFAESGADFLIGLG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS DTCK + ++P EF D ++ G N V P+ +P
Sbjct: 96 GGSPQDTCKGIGIITANP--EFADVLSLE-GVADTKNPSV-PIFGVPTTAGTASETTINY 151
Query: 121 IF-DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ D + + + PI+A +DP T ++P + +G D HA+E +
Sbjct: 152 VVTDTANKRKFVAVDPHDI-PIVAFVDPDLTDSMPRGLKVATGLDALTHAIEGY------ 204
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ P G+ +SD + ++ + K +S + GD+ A M A+ +
Sbjct: 205 ----------ITP---GAWSLSDCLSMQTIRMIAKNLAKSAD--GDIPAGEQMAYASYIT 249
Query: 240 GVGIGNAGVHLCHGLAYPIAGNV 262
G+ N G+ L HG+A+P+ G +
Sbjct: 250 GMAYSNVGLGLVHGMAHPLGGRL 272
>UniRef50_Q97BQ7 Cluster: NADH dependent alcohol dehydrogenase; n=2;
Thermoplasmatales|Rep: NADH dependent alcohol
dehydrogenase - Thermoplasma volcanium
Length = 373
Score = 80.2 bits (189), Expect = 5e-14
Identities = 66/271 (24%), Positives = 112/271 (41%), Gaps = 25/271 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +++ +K VL L+ G + KV+ ++ EP A + D+ + +G
Sbjct: 30 VTDNFLSNTPILKEVLSHLS--GKDIKVFSEISPEPRLSEILKGRELASRLDPDTIIGLG 87
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD K + PD D +P+ K Q +I IP
Sbjct: 88 GGSSMDAAKILFALHEMPDLSPFDI--SPINSIKLH--QKSELIEIPTTSGTGSECSWAA 143
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+F + K I+ + A++DP L +P+ ++ + D HA+E++T+
Sbjct: 144 VFSDDTEERKNEIASPEIMADYAILDPKLVLDLPKGITVNTATDAITHAIEAYTS----- 198
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
Q NP SD A L + + N D+ AR+S+H+ A+MAG
Sbjct: 199 --------------QWRNPYSDAMAEKALDLILNNLPTVLVNPKDINARNSVHIGASMAG 244
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKSFVPEDYG 271
+ N+ + L H L + + K+ E G
Sbjct: 245 ISFSNSQIGLAHALGHALGAIFKTPHGESVG 275
>UniRef50_Q2BFJ3 Cluster: Putative alcohol dehydrogenase; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative alcohol
dehydrogenase - Bacillus sp. NRRL B-14911
Length = 397
Score = 79.8 bits (188), Expect = 7e-14
Identities = 69/261 (26%), Positives = 110/261 (42%), Gaps = 25/261 (9%)
Query: 3 DPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGG 62
DP V ++ V L I + + +V VE + S + A++ D V +GGG
Sbjct: 42 DPGVLQAGIVRRVEQPLADAEIPFIRFTEVGVEASIESVDKGLEIARQTGCDIVVGVGGG 101
Query: 63 SVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIF 122
S +DT K+ L + DYV G K V P+IAIP +
Sbjct: 102 SALDTAKSIGLMLRNA-GNIRDYV----GLDK-VTEPGAPVIAIPTTSGTGSEMTRFAVL 155
Query: 123 DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERG 182
AK + + P LAL DP TL++P ++ +G D HALES+
Sbjct: 156 SDTSAQAKLSVGSMYVCPNLALCDPELTLSLPPHITAATGMDALTHALESY--------- 206
Query: 183 PAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVG 242
N A +P +G + S ++ + K +V +++AR M +A+T+A +
Sbjct: 207 ---VNKATQPISEGLSVQS-------MKLISKSLRLAVIQGENIDARHDMLMASTIAAMA 256
Query: 243 IGNAGVHLCHGLAYPIAGNVK 263
+ + L H LA P+ + K
Sbjct: 257 FSSTRLGLAHALAMPLGAHFK 277
>UniRef50_Q1D0Q5 Cluster: Alcohol dehydrogenase, iron-containing;
n=2; Cystobacterineae|Rep: Alcohol dehydrogenase,
iron-containing - Myxococcus xanthus (strain DK 1622)
Length = 394
Score = 79.8 bits (188), Expect = 7e-14
Identities = 68/258 (26%), Positives = 108/258 (41%), Gaps = 22/258 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V V D L G+ +V+D+V PT+ + + + D VA+G
Sbjct: 46 VTDAGVVKAGLAARVADVLNTAGLACEVFDRVEPNPTERDVFAGLEAYRSHSCDGIVALG 105
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K L + + Y +A G + V + P+IAIP
Sbjct: 106 GGSALDAGKLIQLLTTH-EPPLSRYDDAK-GGDQYVRDDLPPLIAIPTTAGTGSEVGRSG 163
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E+ KT I L P A+ DP TL +P ++ +G D F H LE++ A
Sbjct: 164 VVTLEDTGRKTVIFSPYLLPRAAICDPELTLGLPPGITAATGMDAFTHCLEAYLA----- 218
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G +P++D A + + + +V + D+ AR+ M +AA M G
Sbjct: 219 --------------NGFHPLADAVAIDGIYRVGRSLETAVRDGKDLAARTDMMVAA-MEG 263
Query: 241 VGIGNAGVHLCHGLAYPI 258
G+ CH LA+ +
Sbjct: 264 AMAFQKGLGACHALAHAL 281
>UniRef50_A5D524 Cluster: Alcohol dehydrogenase; n=1; Pelotomaculum
thermopropionicum SI|Rep: Alcohol dehydrogenase -
Pelotomaculum thermopropionicum SI
Length = 400
Score = 79.8 bits (188), Expect = 7e-14
Identities = 67/271 (24%), Positives = 113/271 (41%), Gaps = 27/271 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A+ + ++ +L + G VYD+ + EP D S A FA++ D + G
Sbjct: 42 ITDPGIAAAGLPERLIKALEKEGFKAAVYDQGKPEPDDISCDQAAEFARKEKGDFVIGFG 101
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K P +N K A P+IA+P
Sbjct: 102 GGSSIDIAKVVAQLLVLPGVTDDYLINTTFPKKGA------PIIAVPTTSGTGTECTMYS 155
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + + K + P +AL+DP T+++P V+ +G D HA+E+ A
Sbjct: 156 VITFAKDGIKGFFGTPTILPDMALVDPTLTISMPPGVTASTGIDALSHAIETMMA----- 210
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ NP +D A ++ + + +V ++EAR M + MAG
Sbjct: 211 --------------RQENPFTDAVAIKAIELIAEALPVAVYEGDNLEARVKMSYGSMMAG 256
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKSFVPEDYG 271
+ + G+ H LA+ + G+V VP G
Sbjct: 257 IAFQDPGIVEGHALAHTL-GSV-YHVPHGVG 285
>UniRef50_Q1D8D1 Cluster: Alcohol dehydrogenase, iron-containing;
n=3; Bacteria|Rep: Alcohol dehydrogenase,
iron-containing - Myxococcus xanthus (strain DK 1622)
Length = 392
Score = 79.4 bits (187), Expect = 9e-14
Identities = 66/254 (25%), Positives = 108/254 (42%), Gaps = 22/254 (8%)
Query: 7 ASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMD 66
A+ S + + D+L R G+ V+ V EPT ++ E D VA+GGGS +D
Sbjct: 46 ANPSRARPLHDALERLGLGVTVFS-VDGEPTVERAREGTARVAEAGCDVVVALGGGSALD 104
Query: 67 TCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEE 126
KA ++ + LDY+ +G+G+ + P +AIP + ++
Sbjct: 105 AGKAIAALAAN-GGDPLDYLEV-IGRGQPLTRPSLPFMAIPTTAGTGSEVTRNAVLGSKD 162
Query: 127 IHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPA 186
AK + + P +AL+DP P V SG D +E + +
Sbjct: 163 AKAKASLRSPHMLPRVALVDPDLLTGAPAAVLASSGMDALSQLIEPYLS----------- 211
Query: 187 NPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNA 246
+NP++D AR L+ + R+V + D AR + LA+ G+ + NA
Sbjct: 212 --------ARANPLTDALAREGLRRSARSLRRAVLDGPDAPAREDLALASLFGGLCLANA 263
Query: 247 GVHLCHGLAYPIAG 260
G+ HG A P+ G
Sbjct: 264 GLGAVHGFAAPLGG 277
>UniRef50_A4E817 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 406
Score = 79.4 bits (187), Expect = 9e-14
Identities = 62/263 (23%), Positives = 107/263 (40%), Gaps = 30/263 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +A L + +L GI VY + R PT + ++A +E + + G
Sbjct: 52 VTDPGIARLGLTAPLETALACRGIGVTVYAETRANPTVSNVEEAASLYRERACQAIIGFG 111
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKA---VNIQVKPMIAIPXXXXXXXXXX 117
GGS MD K + P N P+ K + ++ ++ +IA+P
Sbjct: 112 GGSAMDCAKGVGARIAQP--------NKPINKMRGLLRIHRRLPLLIAVPTTAGTGSEVT 163
Query: 118 XXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
+ +E H K I+ L P A+ DP T +P ++ +G D HA+E+F
Sbjct: 164 LAAVITDDETHYKYPINDFVLIPRFAVHDPEFTRGLPASITGRTGMDALTHAVEAFIG-- 221
Query: 178 FTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAAT 237
+ + P + AR +Q + + + + ++ AR +M AA
Sbjct: 222 -----------------RSTTPYTRKMARQAVQLIHDNLLEAYEHGDNMRARRNMLSAAY 264
Query: 238 MAGVGIGNAGVHLCHGLAYPIAG 260
AGV + V H +A+ + G
Sbjct: 265 KAGVAFTRSYVGYVHAIAHSLGG 287
>UniRef50_P41795 Cluster: Ethanolamine utilization protein eutG;
n=23; Enterobacteriaceae|Rep: Ethanolamine utilization
protein eutG - Salmonella typhimurium
Length = 395
Score = 79.4 bits (187), Expect = 9e-14
Identities = 62/239 (25%), Positives = 101/239 (42%), Gaps = 25/239 (10%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
SL G+ V+ EP A+ +E D VA GGGSV+D KA L ++
Sbjct: 72 SLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTN 131
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
PD + + P+IA+P + K ++H +
Sbjct: 132 PDQTLSAMTEHSTLRPRL------PLIAVPTTAGTGSETTNVTVIIDAVSGRKQVLAHAS 185
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGS 197
L P +A++D T VP V+ +G D HA+E+++A+ +
Sbjct: 186 LMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSAL-------------------NA 226
Query: 198 NPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAY 256
P +D A + + K ++V D+ AR +M LA+ MAG+ +AG+ LCH +A+
Sbjct: 227 TPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAH 285
>UniRef50_Q5PKG6 Cluster: Alcohol dehydrogenase; n=22;
Gammaproteobacteria|Rep: Alcohol dehydrogenase -
Salmonella paratyphi-a
Length = 382
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/256 (23%), Positives = 112/256 (43%), Gaps = 25/256 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + ++ +L + ++Y ++D+V PT+ + + D +A G
Sbjct: 36 VTDGQLVKLGLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGFAAYQSAECDYIIAFG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA + ++P A G GK N V P++AI
Sbjct: 96 GGSPIDTAKAVKILTANPGPS-----TAYSGVGKVKNAGV-PLVAINTTAGTAAEMTSNA 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K I + P +A+ D L +P V+ +G D HA+E++ ++
Sbjct: 150 VIIDSARKVKEVIIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSV---- 205
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G++P++D A ++ + + ++V++ ++EAR M +AG
Sbjct: 206 ---------------GAHPLTDANALEAIRLINLWLPKAVDDGHNLEAREQMAFGQYLAG 250
Query: 241 VGIGNAGVHLCHGLAY 256
+ +AG+ L H LA+
Sbjct: 251 MAFNSAGLGLVHALAH 266
>UniRef50_Q3ABB6 Cluster: NADPH-dependent butanol dehydrogenase;
n=1; Carboxydothermus hydrogenoformans Z-2901|Rep:
NADPH-dependent butanol dehydrogenase - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 401
Score = 79.0 bits (186), Expect = 1e-13
Identities = 61/245 (24%), Positives = 111/245 (45%), Gaps = 27/245 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V + + G + +++D+V+ EP + + K + +AIGGGSV+D K L
Sbjct: 64 VKEIFSNAGYHVEMWDEVQPEPPVENIFAGVEAVKNSDASLIIAIGGGSVIDATKVIWLL 123
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMI-AIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
Y PD +F +PV ++ ++ K + AIP + E H K +
Sbjct: 124 YERPDVDFRKL--SPV---DSLGLRKKALFAAIPTTAGTGSEATSAAVIT-EGGH-KMSL 176
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPA 193
SH P A++DP T+++P ++ ++G D HA+ ++ +
Sbjct: 177 SHPEFVPDFAILDPNFTVSLPPNLTLWTGVDALAHAVGAYLS------------------ 218
Query: 194 YQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHG 253
+N +D +A ++ + K+ R V + D+EAR M +AA +AG+ NA + H
Sbjct: 219 -GWANEYTDAYALQAIKLIFKFLPRVVADGRDLEARQKMLIAANLAGLAFSNAAPGIDHA 277
Query: 254 LAYPI 258
L + +
Sbjct: 278 LGHTL 282
>UniRef50_Q0S803 Cluster: Possible Fe-containing alcohol
dehydrogenase; n=8; Bacteria|Rep: Possible Fe-containing
alcohol dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 386
Score = 79.0 bits (186), Expect = 1e-13
Identities = 63/261 (24%), Positives = 109/261 (41%), Gaps = 25/261 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + ++ L G ++ +PT S ++ + E N DS + G
Sbjct: 36 VTDSYLTGTGAADRIMSLLRSAGKEPALFSGTVPDPTTDSLEEGLRIVAEHNADSVIGFG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT KA + S E Y V GKA+ P+IAIP
Sbjct: 96 GGSPMDTAKALAV-LSANGGEMRSYKAPHVYAGKAL-----PIIAIPTTAGSGSEATQFT 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K + PI A++D T+++P +++ +G D HA+E++ +
Sbjct: 150 VISDSASDEKMLCPGLSFLPIAAIVDFELTMSMPPRLTADTGIDALTHAIEAYVS----- 204
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ + P +D A ++T+ K+ + + D AR +M +A+ AG
Sbjct: 205 --------------KKAQPFTDGLALSAIRTIGKHIGTAYADGEDRTAREAMMVASMQAG 250
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
+ N+ V L HG++ PI +
Sbjct: 251 MAFSNSSVALVHGMSRPIGAH 271
>UniRef50_A5D528 Cluster: Alcohol dehydrogenase; n=1; Pelotomaculum
thermopropionicum SI|Rep: Alcohol dehydrogenase -
Pelotomaculum thermopropionicum SI
Length = 395
Score = 78.6 bits (185), Expect = 2e-13
Identities = 64/260 (24%), Positives = 107/260 (41%), Gaps = 23/260 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + V L GI V+++V +P+ + K ++ D V +G
Sbjct: 35 VTDKTMQELGFVDKVKSYLAEAGIESAVFNEVEPDPSRQTVKKGARLMEQFQPDLIVGLG 94
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K ++Y PDA++ D G K N +AIP
Sbjct: 95 GGSSLDAGKGMWIFYEYPDAKWEDIFVPFTGVPKLRN--KARYVAIPSTSGTATEVTLAA 152
Query: 121 IFDYEEI--HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ ++ + K + P +A+ DP T+P V+ +GFD+ HA+E++ ++
Sbjct: 153 VITNRDVVPNVKDFTLSYEVTPDIAICDPELPSTMPPAVTANTGFDVIVHAVEAYVSVNA 212
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
T+ ++D A K+ + N G+ EAR MH A+ M
Sbjct: 213 TD-------------------VTDPIALRSAAMAYKWLPLAFANGGNKEAREKMHTASLM 253
Query: 239 AGVGIGNAGVHLCHGLAYPI 258
AG N + L H A+ I
Sbjct: 254 AGFTFTNTALGLVHSTAHQI 273
>UniRef50_Q892C3 Cluster: Alcetaldehyde dehydrogenase or
NADPH-dependent butanol dehydrogenase; n=6;
Clostridiaceae|Rep: Alcetaldehyde dehydrogenase or
NADPH-dependent butanol dehydrogenase - Clostridium
tetani
Length = 389
Score = 78.2 bits (184), Expect = 2e-13
Identities = 56/262 (21%), Positives = 114/262 (43%), Gaps = 33/262 (12%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + + + V + L ++ I Y ++ + +P I E ++ +A+G
Sbjct: 31 VTDPFMVTSGTISKVTEHLDKSNIEYAIFSDIVPDPPLEIISKGIKAMDEFKPEALIALG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPM--IAIPXXXXXXXXXXX 118
GGS +D KA + Y + + KG +++ + + IAIP
Sbjct: 91 GGSAIDAAKA------------ISYFRSLINKGLNPDMENEKVLFIAIPTTSGTGSEVTS 138
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ ++ + K + + P +A++DP+ TVP ++ +G D+ HA+E++ +
Sbjct: 139 FSVITDKKYNVKYPLVEEIMVPDIAILDPILVKTVPNFITADTGMDVLTHAIEAYVSTDH 198
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
++ SD A ++ + Y ++ N D+ AR MH A+ +
Sbjct: 199 SD-------------------FSDALAEKAIKLVFDYLEKAYKNGDDLTAREKMHNASCI 239
Query: 239 AGVGIGNAGVHLCHGLAYPIAG 260
AG+ NA + + H +A+ + G
Sbjct: 240 AGMAFTNASLGINHSMAHILGG 261
>UniRef50_A3DKJ8 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Staphylothermus marinus F1|Rep: Iron-containing
alcohol dehydrogenase - Staphylothermus marinus (strain
ATCC 43588 / DSM 3639 / F1)
Length = 387
Score = 78.2 bits (184), Expect = 2e-13
Identities = 64/246 (26%), Positives = 113/246 (45%), Gaps = 26/246 (10%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V L ++GI Y VY+ + P + + + KE ++ +AIGGGS++D+ K A L
Sbjct: 53 VTSILDKHGIEYTVYNDIVPNPIVENVEGIVKAYKEFGAEAIIAIGGGSIIDSAKVARLV 112
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
S +DY+ G+ K ++ ++AI + E K GIS
Sbjct: 113 ISG-GGSVVDYL---YGR-KPYPEKLPFLLAINLTHGTGTEIDKYAVVSIVETKEKIGIS 167
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
A P +++ DP +T T+P + Y+ D F H++ES T+
Sbjct: 168 --AGYPNVSIDDPRYTRTLPRNQTIYTSIDAFAHSVESATS------------------- 206
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
S+P + + A ++ + K+ R++ D+EAR + A+ +AG+ I + H+ HGL
Sbjct: 207 TRSSPYTWLLAEEAIKHIVKHLPRALEKPDDLEARYWLLYASMIAGISIDHGVTHIGHGL 266
Query: 255 AYPIAG 260
+ +G
Sbjct: 267 EHVFSG 272
>UniRef50_Q4FSW3 Cluster: Possible iron-containing alcohol
dehydrogenase; n=3; Psychrobacter|Rep: Possible
iron-containing alcohol dehydrogenase - Psychrobacter
arcticum
Length = 441
Score = 77.8 bits (183), Expect = 3e-13
Identities = 62/258 (24%), Positives = 111/258 (43%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L V D L I+YKVYD + +PT ++ + + + DS +AIG
Sbjct: 76 VTDGVLNKLGIPAKVTDYLDSKNISYKVYDGITPDPTFKVVEEGLRISVDAKCDSIIAIG 135
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D K + + +G KA V P+ +P
Sbjct: 136 GGSVIDAAKMIAMSQGNNCKP-----QQLIGILKARKPSV-PLYCVPTTAGTGSEATLGA 189
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ H K + P+ A IDP+ +P ++ +G D+ HALE++ +
Sbjct: 190 VVSDDKTHQKALSIDPRMVPLAAAIDPVIMKGMPAHITADTGIDVLTHALEAWMS----- 244
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
AN ++ Y ++ + V +Q L + + G+++AR +M +AA G
Sbjct: 245 -----ANASVETDYYAASAVKSV-----MQNLPIVY----EDGGNLKAREAMGIAAHYGG 290
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ AG+ H +A+ +
Sbjct: 291 IAFNKAGLGYVHAIAHQL 308
>UniRef50_Q21X13 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Rhodoferax ferrireducens T118|Rep: Iron-containing
alcohol dehydrogenase - Rhodoferax ferrireducens (strain
DSM 15236 / ATCC BAA-621 / T118)
Length = 419
Score = 77.4 bits (182), Expect = 4e-13
Identities = 66/260 (25%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP V+ L + + +LT G + V+D++ + + I K D+ VA G
Sbjct: 62 VTDPIVSGLGLLNRLTQALTEGGTAFVVFDEITQDAPIPLIEKGIAVFKTEGCDAIVAFG 121
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD KA L ++ + + G + ++ V P+ A+P
Sbjct: 122 GGSAMDAAKAIGLSAANHKSP-----RSLAGYFRGLHAPV-PIYAVPTTAGTGSEVTVAA 175
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E K I+ + P +A +DP+ +P V+ +G D HA+E+F T+
Sbjct: 176 VISDPENKMKLVIADTRIVPKMAALDPVLMTGLPRHVTAATGMDALTHAIEAFIGHWSTD 235
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
A A+R Y L+ + K + ++EAR M LAAT AG
Sbjct: 236 DSDRMALAAVRLIYHN------------LRAVYK-------DGNNLEAREQMALAATYAG 276
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ A V H +A+ + G
Sbjct: 277 LAFTRANVGNVHAIAHQLGG 296
>UniRef50_Q9UZ43 Cluster: Alcohol dehydrogenase; n=4;
Thermococcaceae|Rep: Alcohol dehydrogenase - Pyrococcus
abyssi
Length = 375
Score = 77.4 bits (182), Expect = 4e-13
Identities = 63/249 (25%), Positives = 111/249 (44%), Gaps = 24/249 (9%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
+ V D + G Y+ + EP+ + ++ + +E + ++F+A+GGGSV+D KA
Sbjct: 43 LSEVADYVEEAGGVYETIIGLPPEPSVENVEEVLPKVEEFSPETFIALGGGSVIDVAKAV 102
Query: 72 NLYYSDPDAEFLDY-VNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAK 130
++Y P +F + + K + + +IAIP + ++ K
Sbjct: 103 KVFYDAPGLDFDSVAIFSRFKKAQPLPKLKTRLIAIPSTSGAGSEVSAASVI--KKGDTK 160
Query: 131 TGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPAL 190
I L P A++DP +P +V+ SG D+ HA+E++ +
Sbjct: 161 YTIVSPELCPDYAILDPRLPEKMPREVARNSGLDVLVHAIEAYVS--------------- 205
Query: 191 RPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHL 250
+ S P SD A + + + SVN GD +AR +H AATMAG+ N + L
Sbjct: 206 ----KASTPFSDALAVKAARIIFERLEDSVN--GDAKAREEVHYAATMAGIAFLNGRLGL 259
Query: 251 CHGLAYPIA 259
H +++ A
Sbjct: 260 VHAMSHKSA 268
>UniRef50_Q97TN9 Cluster: Alcohol dehydrogenase; n=2; Bacteria|Rep:
Alcohol dehydrogenase - Clostridium acetobutylicum
Length = 396
Score = 77.0 bits (181), Expect = 5e-13
Identities = 57/249 (22%), Positives = 105/249 (42%), Gaps = 24/249 (9%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
+ + D L + I+Y +YD V+ +PT + + F K+ + +A+GGGSVMD K
Sbjct: 63 LNEMFDELKKENISYVIYDDVQPDPTIECIEAVVKFYKKEACEGIIAVGGGSVMDCAKVT 122
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
P V+ G K + ++ P+ +P + H K
Sbjct: 123 GARIVKPKKS----VSQMAGLMK-IRKELPPLYTVPTTAGTGSETTVAAVVTDSSTHLKY 177
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
+S L P A++DP T +P+ ++ +G D HA+E++T
Sbjct: 178 AVSDLCLIPKYAVLDPELTCGLPKNLTAITGMDALTHAVEAYT----------------- 220
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLC 251
+ S+ S +A ++ + + ++ +N +E R +M A+ AGV + V
Sbjct: 221 --NKYSSKESRKYALDAVKLIFENLKKAYDNGKHIEVRENMLKASYYAGVAFTRSYVGYV 278
Query: 252 HGLAYPIAG 260
H +A+ + G
Sbjct: 279 HAIAHAVGG 287
>UniRef50_A5GK32 Cluster: Alcohol dehydrogenase, class IV; n=2;
Synechococcus|Rep: Alcohol dehydrogenase, class IV -
Synechococcus sp. (strain WH7803)
Length = 415
Score = 77.0 bits (181), Expect = 5e-13
Identities = 64/258 (24%), Positives = 108/258 (41%), Gaps = 24/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+T+ + L + +L L R G +V+D+V PT S + + +EG+ DS VA+G
Sbjct: 63 VTNEQLLKLQLPQPLLAELDRIGRPCQVFDQVPDNPTIASVEAGLQAYREGHCDSLVAVG 122
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D KA ++P +L A G + V + P+ +P
Sbjct: 123 GGSVIDCAKAIGARAANP---WLS-CRAMEGLFRVV-LPPPPLACVPTTAGSGSEASIAA 177
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + K ++ L P + +IDP L +P ++ G D HA+E++
Sbjct: 178 VLTDGDRQRKLAMADLKLLPAITVIDPELMLGLPASITAAGGLDALTHAVEAYIG----- 232
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ NP S+ A + + + ++ + D+EAR M LAA AG
Sbjct: 233 --------------RSGNPFSNRRAIAAISAIAHWLPKAYEHGDDLEARLQMALAAHAAG 278
Query: 241 VGIGNAGVHLCHGLAYPI 258
V H LA+ +
Sbjct: 279 EAFTRTNVGYAHALAHAL 296
>UniRef50_Q89NF2 Cluster: Iron alcohol dehydrogenase; n=11;
Alphaproteobacteria|Rep: Iron alcohol dehydrogenase -
Bradyrhizobium japonicum
Length = 395
Score = 76.6 bits (180), Expect = 6e-13
Identities = 58/232 (25%), Positives = 101/232 (43%), Gaps = 25/232 (10%)
Query: 27 KVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYV 86
KV+ V+ EP + + A+ A+E D V GGGS MD K + + D F D V
Sbjct: 79 KVFGDVKPEPDLPNLEKAVAMAREAKPDLVVGFGGGSAMDLAKLVAVLCTS-DVAFADIV 137
Query: 87 NAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALID 146
G++V ++ IP + K + + +A++D
Sbjct: 138 GPEKVAGRSV-----ALMQIPTTSGTGSEAGTRALVTDPVSQNKQAVQSRFMLADIAIVD 192
Query: 147 PLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWAR 206
P T+TVP++V+ +G D H +E++T+ + ++P D++A
Sbjct: 193 PDLTMTVPKEVTAATGVDALAHCVEAYTS-------------------RKAHPTIDLYAL 233
Query: 207 FCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
+ + +Y R+V + GD EAR+ + LA+ G +G H +AYP+
Sbjct: 234 EGARLVGRYLKRAVADGGDREARAGLALASLYGGYCLGPVNTTAGHAVAYPL 285
>UniRef50_Q165D6 Cluster: Alcohol dehydrogenase, iron-containing;
n=6; Rhodobacteraceae|Rep: Alcohol dehydrogenase,
iron-containing - Roseobacter denitrificans (strain ATCC
33942 / OCh 114) (Erythrobactersp. (strain OCh 114))
(Roseobacter denitrificans)
Length = 392
Score = 76.6 bits (180), Expect = 6e-13
Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 22/230 (9%)
Query: 31 KVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPV 90
+ R EP ++A+ K G D VA+GGGSVMD KA + DA LD++ V
Sbjct: 73 RCRAEPDIDMLQEALAQIKAGPVDVVVAVGGGSVMDLGKAL-AALAPGDAPVLDHLEG-V 130
Query: 91 GKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHT 150
GKG + P +AIP + K + + + LA++DP
Sbjct: 131 GKGLPLRAAPLPFVAIPTTAGTGSEVTKNAVIGVPGSGRKVSLRDDRMLARLAIVDPELM 190
Query: 151 LTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQ 210
P+ V+ SG D +E + + + SNP++D R +
Sbjct: 191 DDAPKDVTLASGLDALVQVIEPYLS-------------------KRSNPVTDALCREAIP 231
Query: 211 TLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
R + D +AR M A+ G+ + NAG+ HGLA I G
Sbjct: 232 KAAHALARLLEGE-DAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGG 280
>UniRef50_Q2FPG9 Cluster: Iron-containing alcohol dehydrogenase;
n=2; cellular organisms|Rep: Iron-containing alcohol
dehydrogenase - Methanospirillum hungatei (strain JF-1 /
DSM 864)
Length = 403
Score = 76.6 bits (180), Expect = 6e-13
Identities = 54/260 (20%), Positives = 107/260 (41%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+T P + + V +SL GI Y ++ V P D + K+ D+ +A+G
Sbjct: 57 VTGPKLIKAGWVGDVTESLESEGIQYTIFPDVSPNPRDYEVMNGAELYKKKGCDAVIAVG 116
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + S+ + L++ V+I P+I IP
Sbjct: 117 GGSPIDCAKGIGIVVSN-EQHILEFEGV-----DNVSIPAPPLICIPTTSGSAADVSQFA 170
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I + + K I + P ++L DP+ ++ ++ ++G D H++E++ +
Sbjct: 171 IINDTKRKVKIAIISKKIVPDISLCDPVPLTSLTSDLTAHTGMDALVHSIEAYVS----- 225
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
S+P++D+ A ++ + Y + +N + R L + +AG
Sbjct: 226 --------------NASSPVTDIQALESIRLISAYLPLAYHNPDHIGYRYKTMLGSLLAG 271
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + H +A+ + G
Sbjct: 272 LAFSNASLGAVHAMAHSLGG 291
>UniRef50_O30211 Cluster: Alcohol dehydrogenase, iron-containing;
n=1; Archaeoglobus fulgidus|Rep: Alcohol dehydrogenase,
iron-containing - Archaeoglobus fulgidus
Length = 416
Score = 76.6 bits (180), Expect = 6e-13
Identities = 67/261 (25%), Positives = 109/261 (41%), Gaps = 29/261 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V +L+ V L GI +++D+ + E S K A + D VA+G
Sbjct: 63 VTDKGVRALA--LTVQKMLKGVGIEVEIFDEAKPEVPLSSIKPAAEKMEALQPDLIVAVG 120
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIA-IPXXXXXXXXXXXX 119
GGSVMD KA+ + Y P + + V + + ++ K +A IP
Sbjct: 121 GGSVMDMAKASWILYEAPQTDLTN-----VDAMQPIGLRRKAFLACIPTTAGTGSEATNV 175
Query: 120 XIF--DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
+ D E H K G+ H L P A++DP L +P ++ +G D HA++ +
Sbjct: 176 AVITDDTVEPHRKEGVVHPELYPDFAVLDPRFVLKMPPNLTLGTGLDALSHAVDCYLC-- 233
Query: 178 FTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAAT 237
+ SN ISD A + + KY ++ + + R +AA
Sbjct: 234 -----------------RSSNEISDALAVRATKLVFKYLPLALKYPDNPQIRLKTQIAAM 276
Query: 238 MAGVGIGNAGVHLCHGLAYPI 258
+AG N G+ H +A+ I
Sbjct: 277 IAGSAFSNGGIGTTHAVAHNI 297
>UniRef50_Q65WI4 Cluster: EutG protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: EutG protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 384
Score = 76.2 bits (179), Expect = 8e-13
Identities = 62/260 (23%), Positives = 107/260 (41%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + + L + G+N V EP D A + N + + IG
Sbjct: 36 ITDQGVFNAGLINEPKMLLEQAGVNVHVISDTPPEPPVDKVNDIYKVAMQFNVEMVIGIG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MDT K + ++ A D V+ GK K N + P + IP
Sbjct: 96 GGSAMDTAKLVAILLNNHVA-LRDVVD---GKVKFKNRGI-PTLMIPTTSGTGSEATQNS 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E K GI + P ++DP T +P+ ++ +G D CHA+E + +
Sbjct: 151 IVLVPERELKVGIVDEKMLPNCVILDPKMTTGLPKHITANTGIDALCHAIECYIS----- 205
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +P ++++A ++ + K + + +++AR +M L + + G
Sbjct: 206 --------------KKCSPFTEMFALKSIELIAKSIRIAYEDGHNLQARENMLLGSYLGG 251
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
V I + H L+YP+ G
Sbjct: 252 VSIATSSTVAVHALSYPLGG 271
>UniRef50_Q2RVZ0 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Alphaproteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Rhodospirillum rubrum (strain ATCC 11170
/ NCIB 8255)
Length = 386
Score = 76.2 bits (179), Expect = 8e-13
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 40/238 (16%)
Query: 27 KVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA--ANLYYSDPDAEFLD 84
KV+ +V EP + F + D+ +A+GGGS +D KA A L +P +
Sbjct: 65 KVFGEVVPEPPLQNIAQGARFLADFKPDAILALGGGSAIDAAKAILATLREMEPSRSIV- 123
Query: 85 YVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILAL 144
MIA+P I E K + + P +AL
Sbjct: 124 ------------------MIAVPTTSGTGSEVTSYAIISEPERGIKHPLRSEEIIPDIAL 165
Query: 145 IDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVW 204
+DP ++VP KV+ +G D+ HALE++ A + +N SD +
Sbjct: 166 LDPELVMSVPPKVTADTGMDVITHALEAYVA-------------------REANDFSDAF 206
Query: 205 ARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGNV 262
A L + + N DV AR ++H A+ MAG+ AG+ L HGLA+ I G +
Sbjct: 207 AEKALALAFAHLPTAFANGNDVVARGALHNASCMAGIAFSAAGLGLNHGLAHAIGGRL 264
>UniRef50_Q1GCV3 Cluster: Iron-containing alcohol dehydrogenase;
n=35; Bacteria|Rep: Iron-containing alcohol
dehydrogenase - Silicibacter sp. (strain TM1040)
Length = 398
Score = 76.2 bits (179), Expect = 8e-13
Identities = 60/261 (22%), Positives = 111/261 (42%), Gaps = 21/261 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +A L ++ LD + G+ ++ +V P + + + K G D +A G
Sbjct: 55 VTDKGLADLPVTQSTLDIMEAAGLGRGMFSEVDPNPNEKNLDAGVAAYKAGGHDGVIAFG 114
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + + D+ + +A + P+IA+P
Sbjct: 115 GGSGLDLGKMV-AFMAGQTRPVWDFEDIGDWWTRADADAIAPIIAVPTTAGTGSEVGRAS 173
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ H K I H + P + + DP T+ +P+ ++ +G D F H +E+F++
Sbjct: 174 VITDSATHQKKIIFHPKVLPTVVICDPELTVGMPKFITAGTGLDAFAHCVEAFSS----- 228
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P Y +P+S A ++ ++ Y R+ + D+EAR+ M AA M G
Sbjct: 229 -----------PHY---HPMSQGMALEGMRLVKDYLPRAYADGTDIEARAHMMSAAAM-G 273
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
G+ H +++PI +
Sbjct: 274 ATAFQKGLGAIHAMSHPIGAH 294
>UniRef50_Q0LWU7 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Caulobacter sp. K31|Rep: Iron-containing alcohol
dehydrogenase - Caulobacter sp. K31
Length = 386
Score = 76.2 bits (179), Expect = 8e-13
Identities = 62/259 (23%), Positives = 111/259 (42%), Gaps = 28/259 (10%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
T+P + +P+ +D+L G+ ++ + EPT F A+ + D+ V +GG
Sbjct: 44 TEPTLFLCAPL---VDALEAAGVTVTLWHDLVGEPTLTEFAAALEATRACQADAVVGLGG 100
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GS MD K +D + + + G+A+ + IP I
Sbjct: 101 GSAMDVAKLVAAL-ADGKQRITEVLGTDLLAGRALWLA-----CIPTTAGTGSEVTPIAI 154
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
E+ K G+ L P A +DP T+T+P V+ +G D H +E++
Sbjct: 155 LGDEDEDLKKGVVSPHLVPDAAYLDPALTVTMPPSVTAATGLDALTHCIEAY-------- 206
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
A + ++P+ DV+A ++ + + R+ + D+ ARS+M +A+ G+
Sbjct: 207 -----------ANRFAHPLVDVYALGGIRLIAENLERACTHGDDLAARSAMMIASYYGGL 255
Query: 242 GIGNAGVHLCHGLAYPIAG 260
+G H LAYP+ G
Sbjct: 256 CLGPVNTAAVHALAYPLGG 274
>UniRef50_A5TRI3 Cluster: Alcohol dehydrogenase; n=1; Fusobacterium
nucleatum subsp. polymorphum ATCC 10953|Rep: Alcohol
dehydrogenase - Fusobacterium nucleatum subsp.
polymorphum ATCC 10953
Length = 369
Score = 76.2 bits (179), Expect = 8e-13
Identities = 64/260 (24%), Positives = 113/260 (43%), Gaps = 38/260 (14%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L K + + I YK++D+V V+P+ A++ + D V IG
Sbjct: 31 VTDSIMYKLGMTKKFENIFNKKNIEYKIFDEVEVDPSFEVVDKALNKVIDFLPDIIVGIG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT K+ + K N+ + P+IA+P
Sbjct: 91 GGSSLDTAKSIKYFI------------------KKSNLHI-PLIALPTTSGTGSEVTSYA 131
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ + K + + + P A++DP T T+P+ V SG D HA+ES+T
Sbjct: 132 VLTDKKNNIKIPLKDDEMIPEYAILDPELTKTLPKSVVADSGIDALTHAIESYTC----- 186
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+G+N + V+A ++ + K +R + D EAR+ M A+ +AG
Sbjct: 187 --------------KGANFYTKVYALSAIRLIFKNLLRMYRDIKDEEARTEMAKASCIAG 232
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+G+ + H +A+ I G
Sbjct: 233 FAFEKSGLGINHSVAHAIGG 252
>UniRef50_A3J834 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Marinobacter|Rep: Iron-containing alcohol
dehydrogenase - Marinobacter sp. ELB17
Length = 380
Score = 76.2 bits (179), Expect = 8e-13
Identities = 62/232 (26%), Positives = 99/232 (42%), Gaps = 28/232 (12%)
Query: 32 VRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA-ANLYYSDPDAEFLDYVNAPV 90
+ EP + AI K D + IGGGSVMDT K A + S D + ++ V
Sbjct: 63 IEKEPDLKTLMAAIDQGKLLGIDLVLGIGGGSVMDTAKVLAAMLPSQTD--LISHLEV-V 119
Query: 91 GKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHT 150
G G ++ + P+I +P + D E K + N L P LAL+DP T
Sbjct: 120 GSGLPLSAKRLPLILVPTTSGTGAEVTRNAVIDIPEAQRKVSLRDNQLLPDLALVDPALT 179
Query: 151 LTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQ 210
P +VS YSG D +E + + SN +D+ C++
Sbjct: 180 DNCPRQVSLYSGLDAVTQVIEPYLS-------------------SRSNLFTDM---LCME 217
Query: 211 TLQKYF--VRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
+ K ++ + + EAR S+ + G+ + N+G+ + HG+A P+ G
Sbjct: 218 AIPKGLRALKQLMDRESEEARDSLAQVSLFGGLALANSGLGVVHGIAGPLGG 269
>UniRef50_P13604 Cluster: NADPH-dependent butanol dehydrogenase;
n=29; cellular organisms|Rep: NADPH-dependent butanol
dehydrogenase - Clostridium saccharobutylicum
Length = 388
Score = 76.2 bits (179), Expect = 8e-13
Identities = 59/242 (24%), Positives = 106/242 (43%), Gaps = 24/242 (9%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
VL L GI K+ + V +P+ + ++ D +A+GGGS +D KA ++
Sbjct: 46 VLGYLKEAGIEVKLIEGVEPDPSVETVFKGAELMRQFEPDWIIAMGGGSPIDAAKAMWIF 105
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
Y P+ F D + P + N + K +AIP + + K ++
Sbjct: 106 YEHPEKTF-DDIKDPFTVPELRN-KAK-FLAIPSTSGTATEVTAFSVITDYKTEIKYPLA 162
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
+ P +A++D T+P K++ ++G D HA+E++ A
Sbjct: 163 DFNITPDVAVVDSELAETMPPKLTAHTGMDALTHAIEAYVATL----------------- 205
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+P +D A ++ + ++ +S GD EAR MH A +AG+ NA + +CH +
Sbjct: 206 --HSPFTDPLAMQAIEMINEHLFKSY--EGDKEAREQMHYAQCLAGMAFSNALLGICHSM 261
Query: 255 AY 256
A+
Sbjct: 262 AH 263
>UniRef50_P38945 Cluster: NAD-dependent 4-hydroxybutyrate
dehydrogenase; n=10; Bacteria|Rep: NAD-dependent
4-hydroxybutyrate dehydrogenase - Clostridium kluyveri
Length = 371
Score = 76.2 bits (179), Expect = 8e-13
Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 29/229 (12%)
Query: 35 EPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGK 94
EP+D + I + ++ +A+GGGSV+D K +L Y+D + + GK
Sbjct: 61 EPSDEMINNIIKDIGDKQYNRIIAVGGGSVIDIAKILSLKYTDDSLDLFE--------GK 112
Query: 95 AVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVP 154
++ K +I +P + + + H K GI+ + L A++ P +P
Sbjct: 113 VPLVKNKELIIVPTTCGTGSEVTNVSVAELKRRHTKKGIASDELYATYAVLVPEFIKGLP 172
Query: 155 EKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQK 214
K S D HA E++ + +NP +D+++ ++ +
Sbjct: 173 YKFFVTSSVDALIHATEAYVS-------------------PNANPYTDMFSVKAMELILN 213
Query: 215 YFVRSVNNSGD--VEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGN 261
+++ V D VE + + AG+ GNAGV H L+YPI GN
Sbjct: 214 GYMQMVEKGNDYRVEIIEDFVIGSNYAGIAFGNAGVGAVHALSYPIGGN 262
>UniRef50_A3PTT4 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Mycobacterium|Rep: Iron-containing alcohol
dehydrogenase - Mycobacterium sp. (strain JLS)
Length = 401
Score = 75.8 bits (178), Expect = 1e-12
Identities = 59/194 (30%), Positives = 90/194 (46%), Gaps = 10/194 (5%)
Query: 1 MTDPNVASLSP-MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+TD + +P + AVL +L+ +G+ DK EPT A + D+ VA+
Sbjct: 45 LTDQGIEHHNPAVAAVLTTLSTSGLTVSRLDKAPGEPTIEMVDAATARMTSESVDAIVAL 104
Query: 60 GGGSVMDTCKAANLYYSD--PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXX 117
GGGSV+DT KAA L + EFLD +A AV P+IA+P
Sbjct: 105 GGGSVIDTAKAARLCHQQGLTFGEFLD--SARTYPAPAV-----PLIAVPTTAGTGSEVS 157
Query: 118 XXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
+ + K GI+H +R A++DP+ T ++P ++ +G D A+ + A
Sbjct: 158 GGAVVSDPQAGRKAGIAHPNMRAQYAVVDPVLTWSMPPVMTANTGIDALAQAMAAVIAKV 217
Query: 178 FTERGPAPANPALR 191
T G A A A+R
Sbjct: 218 RTPIGDAIALEAVR 231
>UniRef50_A3HBD1 Cluster: Iron-containing alcohol dehydrogenase;
n=26; cellular organisms|Rep: Iron-containing alcohol
dehydrogenase - Pseudomonas putida (strain GB-1)
Length = 418
Score = 75.8 bits (178), Expect = 1e-12
Identities = 61/260 (23%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++DP V + + V SL GI+Y +Y V P ++ + D VA+G
Sbjct: 72 VSDPGVIAAGWVADVEASLQAQGIDYCLYTDVSPNPRVEEVMLGAEIYRQNHCDVIVAVG 131
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD KA + + L++ + + + P+I IP
Sbjct: 132 GGSPMDCGKAIGIVVAH-GRSILEFEGVDM-----IRVPSPPLILIPTTAGTSADVSQFV 185
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I ++ K I A+ P ++LIDP TL++ +S +G D HA+E+F +
Sbjct: 186 IISNQQERMKFSIVSKAVVPDVSLIDPQTTLSMDPFLSACTGIDALVHAIEAFVS----- 240
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G P++D A ++ + V + N D+ R + L + AG
Sbjct: 241 --------------TGHGPLTDPHALEAMRLINGNLVEMIANPTDIALREKIMLGSMQAG 286
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + H +++ + G
Sbjct: 287 LAFSNAILGAVHAMSHSLGG 306
>UniRef50_A2U751 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Bacillus coagulans 36D1|Rep: Iron-containing
alcohol dehydrogenase - Bacillus coagulans 36D1
Length = 383
Score = 75.8 bits (178), Expect = 1e-12
Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 24/231 (10%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
V+ ++ PT + D +E D VAIGGGSV+D KAA P + +
Sbjct: 62 VFSSIQQNPTVKNTDDCARMLREEGADFAVAIGGGSVLDCAKAAACIAQTPYS-----AS 116
Query: 88 APVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDP 147
A + K + + P+IAIP + + K IS + L P AL+DP
Sbjct: 117 AFLAKAQTLVQPGIPLIAIPTTSGTASEVTNVSVLTDTKKGIKALISSDFLYPAYALVDP 176
Query: 148 LHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
TL+ P+ V+ SG D+ H+LE++ + P +D+ A
Sbjct: 177 ELTLSCPKHVTASSGLDVLAHSLEAYYG-------------------KKHQPYTDMAAER 217
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
+ +Y + + + G+++AR+ M A+ AG+ H +YP+
Sbjct: 218 AAALVFEYLLPAYHEPGNLQARAKMSEASVTAGLAFNMTQTAAAHACSYPL 268
>UniRef50_UPI000051A9D0 Cluster: PREDICTED: similar to alcohol
dehydrogenase, iron containing, 1, partial; n=1; Apis
mellifera|Rep: PREDICTED: similar to alcohol
dehydrogenase, iron containing, 1, partial - Apis
mellifera
Length = 123
Score = 75.4 bits (177), Expect = 1e-12
Identities = 32/58 (55%), Positives = 43/58 (74%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
MTD N+ +L P+K +DSLT++GI VYD VRVEPT+ S KD+I + K G FD+F+A
Sbjct: 66 MTDSNLINLPPVKTAMDSLTKHGIQTSVYDNVRVEPTEQSLKDSIEYVKRGKFDAFIA 123
>UniRef50_Q4Q784 Cluster: Alcohol dehydrogenase, putative; n=3;
Leishmania|Rep: Alcohol dehydrogenase, putative -
Leishmania major
Length = 399
Score = 75.4 bits (177), Expect = 1e-12
Identities = 66/260 (25%), Positives = 108/260 (41%), Gaps = 24/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + +D + + G +Y V PT ++A ++ D VA+G
Sbjct: 49 VTDAMIMKLGLVDDFIDEMKKQGTELAIYKDVLPNPTIDMVEEASVLYRKNRCDYLVAVG 108
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSVMD K + + P L Y+ + V + P+IA+P
Sbjct: 109 GGSVMDCAKLIGVRQARPRTP-LPYMRGLL----RVLWPLPPLIAVPTTAGTGSECTIAA 163
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K + L P ++DP TLT+P+ V+ +G D H +E++T + F
Sbjct: 164 VVSDPAKKDKLVVMDPFLTPSHCVLDPALTLTLPKFVTATAGMDALTHVVEAYTNV-FHY 222
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
R A ALR ++ L KY + + ++EAR M A+ +AG
Sbjct: 223 RTVDKA--ALR----------------AMELLAKYLPCAYKDGSNLEAREKMLHASYLAG 264
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ AGV H A+ + G
Sbjct: 265 LSFTRAGVGNVHAAAHAVGG 284
>UniRef50_Q1IUR6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Acidobacteria bacterium Ellin345|Rep:
Iron-containing alcohol dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 881
Score = 74.9 bits (176), Expect = 2e-12
Identities = 63/221 (28%), Positives = 101/221 (45%), Gaps = 30/221 (13%)
Query: 43 DAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKP 102
+A++F K D +A+GGGSV+D K L Y PDA F + + + K V +Q
Sbjct: 535 EALNFYKA---DQIIALGGGSVIDAAKMMKLKYESPDANFEELGSPFLDLRKRV-VQFPT 590
Query: 103 -------MIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPE 155
+IA+P + + K ++ +L P +A++DP +++P+
Sbjct: 591 EKKHHARLIAVPTTSGTGSEVTPFAVLFDKARQRKITLADYSLSPDVAIVDPQFVMSMPK 650
Query: 156 KVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKY 215
++ +G D HALE+ + A+P Y SN + + F KY
Sbjct: 651 GLTADTGIDCLTHALEAGVS--------NYASP-----YTDSNAMQAIRLAF------KY 691
Query: 216 FVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAY 256
+ N D EAR++MH AAT+A + NA V L H LA+
Sbjct: 692 LPIAYENPQDEEARNTMHNAATIAAIAFSNASVGLNHALAH 732
>UniRef50_A3DIK0 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
Iron-containing alcohol dehydrogenase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 368
Score = 74.9 bits (176), Expect = 2e-12
Identities = 64/260 (24%), Positives = 114/260 (43%), Gaps = 29/260 (11%)
Query: 1 MTDPNVASLS-PMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+T N A S V++ L GI+Y++YD+V P+ + K+ A++ + D + I
Sbjct: 35 VTGKNSAKASGAFSDVVEVLEEYGIDYEIYDRVANNPSLENVKEGGEAARKFDADFIIGI 94
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLD-YVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXX 118
GGGS +D KA + ++ D E +D Y N V + K + P+IAIP
Sbjct: 95 GGGSPLDASKAVAVLATN-DIEPVDLYKN--VFENKPL-----PIIAIPTTAGTGSEVTP 146
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
I +++ K + P +A ID +T ++ + + + D F HALE +
Sbjct: 147 YSILTRDDMKTKKSFGNEDTFPAVAFIDARYTESMSYETTVDTALDAFTHALEGYLG--- 203
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
+ S P+SD+ A ++ + +NN D + R + + +
Sbjct: 204 ----------------RRSTPVSDILAVEAIRIFGECLENLLNNKFDYDVREKLLYMSML 247
Query: 239 AGVGIGNAGVHLCHGLAYPI 258
G+ I + G + HG+ Y +
Sbjct: 248 GGMVISHTGTTIIHGMGYSL 267
>UniRef50_Q2G4J2 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Novosphingobium aromaticivorans (strain
DSM 12444)
Length = 385
Score = 74.5 bits (175), Expect = 3e-12
Identities = 63/258 (24%), Positives = 107/258 (41%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + +L+ L GI V+D +PT + A+ +E D + G
Sbjct: 35 VTDAFLVQSGMVARMLEVLDGAGIAATVFDATVPDPTVAVVEQALGALREAECDCVIGFG 94
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA +P A + + AP ++ P+IA+P
Sbjct: 95 GGSPIDTSKAIAALALEPRA--VQSMKAPA----TTDVPGLPIIAVPTTAGTGSEATKFT 148
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E K + A P +A++D T+ P +++ +G D HA+E++ +
Sbjct: 149 IVTDEATSEKMLCAGLAFLPTIAIVDFELTMGKPARLTADTGIDSLTHAIEAYVS----- 203
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ +NP SD A ++ + + G+ AR +M + A AG
Sbjct: 204 --------------KKANPFSDAMAISAMKLIAPNIRTACAEPGNRAAREAMMIGAHHAG 249
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NA V L HG++ PI
Sbjct: 250 IAFSNASVALVHGMSRPI 267
>UniRef50_A1U008 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Gammaproteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8)(Marinobacter
hydrocarbonoclasticus (strain DSM 11845))
Length = 412
Score = 74.5 bits (175), Expect = 3e-12
Identities = 63/252 (25%), Positives = 104/252 (41%), Gaps = 25/252 (9%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
M+++ SL R GI + +Y + EP + A D + GGGS +D K
Sbjct: 74 MRSMERSLERAGIEFTIYPAITQEPDESVVTSATELLTRNQADFVLGFGGGSALDAAKVI 133
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
L S + L + P G+ +V + A+P + + K
Sbjct: 134 ALAGSCQSS--LQQLAEPGFGGR----RVIGLGAVPTTAGTGSEVTDISVIMRADRKHKY 187
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
I L P LA++DP L +P V+ +G D HA+E++ A
Sbjct: 188 VIKQVDLMPDLAIVDPGLMLNLPPLVTAATGIDALTHAIEAYAA---------------- 231
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLC 251
+ S+P++ A +Q++ + V N GDV AR +M AA AG+ N+G+ L
Sbjct: 232 ---RSSHPLAKALAICAVQSIAEALPVVVGNGGDVAARLTMATAAYKAGLAFSNSGLGLV 288
Query: 252 HGLAYPIAGNVK 263
H +++ I +
Sbjct: 289 HAISHQIGARYR 300
>UniRef50_O86272 Cluster: Alcohol-acetaldehyde dehydrogenase; n=17;
Lactobacillales|Rep: Alcohol-acetaldehyde dehydrogenase
- Lactococcus lactis
Length = 903
Score = 74.1 bits (174), Expect = 3e-12
Identities = 65/279 (23%), Positives = 112/279 (40%), Gaps = 32/279 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLT--RNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
+ DP + + VL+ L + +Y V+ +PT K+ D+ +
Sbjct: 507 VADPGMVKFGFVDKVLEQLAIRPTQVETSIYGSVQPDPTLSEAIAIARQMKQFEPDTVIC 566
Query: 59 IGGGSVMDTCKAANLYYS---------DPDAEFLDYVNAPVGKGKAVNIQV--------K 101
+GGGS +D K L Y DA + K + ++
Sbjct: 567 LGGGSALDAGKIGRLIYEYDARGEADLSDDASLKELFQELAQKFVDIRKRIIKFYHPHKA 626
Query: 102 PMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYS 161
M+AIP + +E H K ++ L P +A++DP +TVP++ ++S
Sbjct: 627 QMVAIPTTSGTGSEVTPFAVITDDETHVKYPLADYQLTPQVAIVDPEFVMTVPKRTVSWS 686
Query: 162 GFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVN 221
G D HALES+ ++ ++ + A++ ++ L Y
Sbjct: 687 GIDAMSHALESYVSVMSSDYTKPISLQAIKLIFEN------------LTESYHYDPAHPT 734
Query: 222 NSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
G +AR +MH AAT+AG+ NA + + H LA+ I G
Sbjct: 735 KEGQ-KARENMHNAATLAGMAFANAFLGINHSLAHKIGG 772
>UniRef50_A6BEI0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 385
Score = 74.1 bits (174), Expect = 3e-12
Identities = 64/259 (24%), Positives = 105/259 (40%), Gaps = 25/259 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D + L ++ VLD + GI + + PT A KE S VA+G
Sbjct: 40 VSDRGLEKLGVIQKVLDIVEAEGIETVSFLDILPNPTVDMVNAATKVYKESGATSIVALG 99
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS MD KA + + +Y A + G ++P+IAIP
Sbjct: 100 GGSPMDVAKAVGVL-ARYGGSITEYEGAHLVPGP-----IEPIIAIPTTAGTGSEVTAFS 153
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + K + L P AL+DP ++VP V+ G D HA E++T++
Sbjct: 154 VITDTSRNYKLTVFSYELLPKYALLDPEMIMSVPPMVAASCGIDALIHAWEAYTSL---- 209
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G++P SD A ++ + R V N D EA +M + AG
Sbjct: 210 ---------------GASPFSDAMAEKAMELIGGNIRRFVANRKDEEAACAMMSGSMFAG 254
Query: 241 VGIGNAGVHLCHGLAYPIA 259
+ A + H +++P++
Sbjct: 255 IAFAWARLGDVHAMSHPVS 273
>UniRef50_A4BN71 Cluster: Alcohol dehydrogenase, class IV; n=6;
Proteobacteria|Rep: Alcohol dehydrogenase, class IV -
Nitrococcus mobilis Nb-231
Length = 417
Score = 74.1 bits (174), Expect = 3e-12
Identities = 58/258 (22%), Positives = 109/258 (42%), Gaps = 21/258 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD ++ +L ++ L +L G+ + +V+ P + + + + G D VA G
Sbjct: 69 VTDADLRALPMIEDTLSALRNAGLAAALCAEVQGNPVEANVDAGVVAYRSGGHDGVVACG 128
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA L A + D+ + +A + P+IAIP
Sbjct: 129 GGSALDVAKAVALMVGQRRAIW-DFEDVDENWRRANAEAIAPVIAIPTTAGTGSEVGRAA 187
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ H K + H + P ++DP T+ +P ++ +G D F H E++ A
Sbjct: 188 VIINPADHRKVIVFHPRMLPQAVILDPKVTVELPAPLTAATGMDAFVHCFEAWCA----- 242
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G +P++D A ++ + R+ + GD++AR+ M AA+M
Sbjct: 243 --------------SGFHPLADGLALQGMRLIADALPRAYRDGGDLQARTHMLAAASMGA 288
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ G+ H +A+ +
Sbjct: 289 LAF-QKGLGAVHAIAHAV 305
>UniRef50_O29908 Cluster: Alcohol dehydrogenase, iron-containing;
n=1; Archaeoglobus fulgidus|Rep: Alcohol dehydrogenase,
iron-containing - Archaeoglobus fulgidus
Length = 395
Score = 74.1 bits (174), Expect = 3e-12
Identities = 73/265 (27%), Positives = 111/265 (41%), Gaps = 29/265 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD ++ +S ++ V +L I +V+D+V EP+ + A+E + +A+G
Sbjct: 45 VTDKVLSEMSYLEEVKKNLKAERI--EVFDEVEPEPSIETALKCSKVARELDAQLIIALG 102
Query: 61 GGSVMDTCKAANLYYS-DPDAEFLDYVNAPVGKGKAVNIQVK-PMIAIPXXXXXXXXXXX 118
GGSVMD K A + D D EF+ P + Q K +IAIP
Sbjct: 103 GGSVMDVAKMARILMELDVDPEFI----TPFTDLYELGFQKKAKLIAIPTTSGTGADATW 158
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ + K ++ P L ++D +P K+ +G D HA+E
Sbjct: 159 AMVLTDTKEKRKVLPANREAIPDLTILDYRFVENLPPKLVAGTGMDALTHAIEG------ 212
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
AL P N SD ++ + +S N GD EAR+ MH AATM
Sbjct: 213 ----------ALAP---WRNDFSDAMCEKAIELIFDNLEKSYN--GDKEARAKMHHAATM 257
Query: 239 AGVGIGNAGVHLCHGLAYPIAGNVK 263
AG+G GN+ V H L + K
Sbjct: 258 AGMGFGNSQVGPVHSLGHAFGAYFK 282
>UniRef50_Q18QL8 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Clostridiales|Rep: Iron-containing alcohol
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 362
Score = 73.7 bits (173), Expect = 4e-12
Identities = 59/244 (24%), Positives = 104/244 (42%), Gaps = 27/244 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V +L+ G+ Y ++D+V P+ + + A K D + IGGGS MD KA ++
Sbjct: 44 VTKALSETGVEYILFDEVEQNPSLETIEKAGAIGKANKADFVIGIGGGSPMDAAKAIAVF 103
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
+P+ + N G+ K +I P++ + I + K +
Sbjct: 104 IKNPE---ITKDNIFSGQ-KLASI---PVVVVATTAGTGSEVTQYSIITSNKERTKKNLG 156
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
+ P +A +D +T +P ++ + D F H +E + +
Sbjct: 157 QR-IFPKVAFLDCKYTYDLPYDITVNTALDAFTHLVEGYLS------------------- 196
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
S P+SD++ + + F R +NN D E R M LA+T+AG+ I +G L HG+
Sbjct: 197 SKSTPMSDIYGEKGFELFKDCFDRLLNNELDKEFRRKMMLASTLAGMLISQSGTSLPHGM 256
Query: 255 AYPI 258
Y +
Sbjct: 257 GYAL 260
>UniRef50_A5ZA28 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 359
Score = 73.7 bits (173), Expect = 4e-12
Identities = 66/246 (26%), Positives = 103/246 (41%), Gaps = 29/246 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAAN-- 72
V+++L I Y VYD V P+ + +A + D + IGGGS MD KA
Sbjct: 48 VINALKSKNIKYTVYDGVEENPSVETVMEAREIGVKAGCDFIIGIGGGSPMDAAKAIGVM 107
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
+Y+ + + +FL Y + N Q P+I +P + K
Sbjct: 108 IYHKNENKDFL-YKSVS-------NSQSLPVIEVPTTCGTGSEVTTVAVLTVHNEKTKKS 159
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
+SH + P +AL+D + P KV + D H +ES TE A L
Sbjct: 160 MSHR-IFPRMALVDEKYIKNAPLKVICDTAIDALAHIVESCINNNATEYSKMFAKEGL-- 216
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
+ W++F K + + D + + M+ A+T+AG+ I +AG L H
Sbjct: 217 ---------EAWSKF------KDVLLGNREATDEDFHNMMY-ASTLAGMCIAHAGTSLPH 260
Query: 253 GLAYPI 258
GL+YPI
Sbjct: 261 GLSYPI 266
>UniRef50_A6TJU4 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Alkaliphilus metalliredigens QYMF|Rep:
Iron-containing alcohol dehydrogenase - Alkaliphilus
metalliredigens QYMF
Length = 386
Score = 73.3 bits (172), Expect = 6e-12
Identities = 58/259 (22%), Positives = 104/259 (40%), Gaps = 25/259 (9%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
T + + V + + G +Y V +R EP + + + + + VA+GG
Sbjct: 40 TGKEILKIGICDKVFEVIRECGADYDVISDIRPEPGTVDVEKVLKQLNQSDGELVVAVGG 99
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GSVMD K Y + + ++ P + +P I
Sbjct: 100 GSVMDMAKLCAAMKG------ASYTIHQLLEDNSIMENGLPTVMVPTTCGTGSESTFNSI 153
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
E K GI + + ++D +P+ + +G D HA+E FT+
Sbjct: 154 VAVESKQLKVGIVNTNMMADYVILDSSMIAGLPKHIVASTGVDALAHAVECFTS------ 207
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
+NP SD+ A+ + + + V+S + G++EA+++M AA +AGV
Sbjct: 208 -------------NRANPFSDLVAKEASKLIFENIVKSYHEPGNMEAKTNMLRAAFLAGV 254
Query: 242 GIGNAGVHLCHGLAYPIAG 260
I ++G H L+YP+ G
Sbjct: 255 AIASSGTTAVHALSYPLGG 273
>UniRef50_A6D0S9 Cluster: Alcohol dehydrogenase; n=1; Vibrio
shilonii AK1|Rep: Alcohol dehydrogenase - Vibrio
shilonii AK1
Length = 380
Score = 73.3 bits (172), Expect = 6e-12
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 25/241 (10%)
Query: 17 DSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYS 76
D L + +N ++ VR P + A E + GGGS +DT KA + +
Sbjct: 50 DKLLSSSLNLMLFKDVRPNPDTNTVNSAYKMYSESEAQFIIGFGGGSSIDTAKAIKILSA 109
Query: 77 DPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHN 136
+ D Y G K + + V P+ AI + E H K I +
Sbjct: 110 N-DGPIAAYN----GIEKVITLGV-PLYAINTTAGTAAEVTSNAVITDTETHVKHVIISD 163
Query: 137 ALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQG 196
+ P +++ DP L VP + +G D HA+ESF ++ G
Sbjct: 164 KIIPEISVNDPSVMLGVPRGTTAATGIDALTHAVESFVSV-------------------G 204
Query: 197 SNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAY 256
++ ++D + ++T+ + ++V++ +EAR M +AG+ +AG+ + H +A+
Sbjct: 205 AHKLTDYISLEAIKTIAQNLPKAVDDGTSIEAREMMAYGQFIAGLSFNSAGLGMVHAMAH 264
Query: 257 P 257
P
Sbjct: 265 P 265
>UniRef50_A1HIY6 Cluster: Iron-containing alcohol dehydrogenase;
n=10; Bacteria|Rep: Iron-containing alcohol
dehydrogenase - Ralstonia pickettii 12J
Length = 389
Score = 73.3 bits (172), Expect = 6e-12
Identities = 66/264 (25%), Positives = 111/264 (42%), Gaps = 32/264 (12%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNF--DSFVA 58
+T P + + V+ +L I ++ V EPT + + + + F D+ ++
Sbjct: 40 ITQPVMEQNGVIGRVVQALAARDIEARIVRGVEPEPTIENV-ETVFREQIAPFAPDAILS 98
Query: 59 IGGGSVMDTCK--AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
IGGGSV+D K A L P E+L + K I P++ +P
Sbjct: 99 IGGGSVLDAAKLFAVRLTNEQPLREWLG-----IDLIKRPGI---PLVLVPTTAGTGSEV 150
Query: 117 XXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
I + K GI L P L ++D T +P+ ++ +G D F H+LES+ +
Sbjct: 151 TPNAIVTLPDEELKVGIVSRHLLPQLVILDAELTFDLPKPITAATGIDAFVHSLESYIST 210
Query: 177 PFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAA 236
+NP+SD++A ++ + V + N V+AR +M L +
Sbjct: 211 K-------------------ANPVSDMFAMESMRLIGANLVEAYQNGRSVKAREAMMLGS 251
Query: 237 TMAGVGIGNAGVHLCHGLAYPIAG 260
G+ + AG H LAYP+ G
Sbjct: 252 MYGGLALTAAGTAAVHALAYPLGG 275
>UniRef50_Q9X022 Cluster: Alcohol dehydrogenase, iron-containing;
n=2; Thermotoga|Rep: Alcohol dehydrogenase,
iron-containing - Thermotoga maritima
Length = 359
Score = 72.9 bits (171), Expect = 8e-12
Identities = 62/251 (24%), Positives = 110/251 (43%), Gaps = 33/251 (13%)
Query: 8 SLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDT 67
SL +K +LD I+Y+++D+V P+ + A+ + +FD V +GGGS MD
Sbjct: 45 SLDDLKKLLDETE---ISYEIFDEVEENPSFDNVMKAVERYRNDSFDFVVGLGGGSPMDF 101
Query: 68 CKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEI 127
KA + + D D + K P++ IP I E
Sbjct: 102 AKAVAVLLKEKDLSVEDLYDREKVK------HWLPVVEIPTTAGTGSEVTPYSILTDPEG 155
Query: 128 HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPAN 187
+ K G + + P+ A +DP +T ++ ++++ +G D HA+E + +
Sbjct: 156 N-KRGCT--LMFPVYAFLDPRYTYSMSDELTLSTGVDALSHAVEGYLS------------ 200
Query: 188 PALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAG 247
+ S P SD A ++ + + +++ G+ EAR M +A+ +AG+ I G
Sbjct: 201 -------RKSTPPSDALAIEAMKIIHRNLPKAI--EGNREARKKMFVASCLAGMVIAQTG 251
Query: 248 VHLCHGLAYPI 258
L H L YP+
Sbjct: 252 TTLAHALGYPL 262
>UniRef50_Q9KFE7 Cluster: NAD-dependent methanol dehydrogenase;
n=10; Bacteria|Rep: NAD-dependent methanol dehydrogenase
- Bacillus halodurans
Length = 382
Score = 72.9 bits (171), Expect = 8e-12
Identities = 61/260 (23%), Positives = 110/260 (42%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D VA+ ++ V++ + + + + V +P D + + D+ + +G
Sbjct: 36 VSDRGVANAGWLEKVMELCKESHLPFATFVGVTTDPKDREVEQGCQVFVQHECDAIIGVG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D KA + ++ A DY + K K + PMI I
Sbjct: 96 GGSVLDVAKAIAILATNGGA-ISDYEG--IDKIKK---PLPPMIMIMTTAGSGSEVSQFS 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I K I L P +A+IDP +T ++ +G D+ HA+E++ +I T
Sbjct: 150 IIVDSNRKKKMTIVSKTLVPDIAIIDPYTLVTKDSSLTATTGMDVLTHAIEAYVSIAAT- 208
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P++DV A+ L +Y SV + + EA+ +M +A+ AG
Sbjct: 209 ------------------PLTDVQAKNALILCAQYLRPSVASKTNTEAKEAMAMASLQAG 250
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + H +++ I G
Sbjct: 251 LAFSNAILGAAHAISHAIGG 270
>UniRef50_Q88TC1 Cluster: 1,3-propanediol dehydrogenase; n=8;
Lactobacillales|Rep: 1,3-propanediol dehydrogenase -
Lactobacillus plantarum
Length = 390
Score = 72.9 bits (171), Expect = 8e-12
Identities = 64/262 (24%), Positives = 110/262 (41%), Gaps = 27/262 (10%)
Query: 1 MTDPNVASL--SPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVA 58
+TD + SL + V SL GI+Y +Y++V P + + + DS +
Sbjct: 39 VTDKFLESLPDGAVAQVRRSLDAAGIDYVIYNQVEPNPKIHNIQAVKALYQANQADSLIT 98
Query: 59 IGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXX 118
IGGGS DT K A + ++ D + G N + P+IA+
Sbjct: 99 IGGGSAHDTGKGAGIIMTNGDD-----ITKLAGIETLKN-ALPPLIAVNTTAGTGSELTR 152
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ EE H K ++ P+++ DP L VP+ ++ +G D F A+E F ++
Sbjct: 153 HCVITNEETHYKFVVASWRNMPLVSFNDPTLMLDVPKGLTAATGMDAFVQAIEPFVSV-- 210
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
NPI+D ++ ++ +V N ++EAR+ M A +
Sbjct: 211 -----------------DHNPITDSQCIQAIKLIETSLREAVANGHNLEARTHMVEAEML 253
Query: 239 AGVGIGNAGVHLCHGLAYPIAG 260
AG+ NA + H +A+ + G
Sbjct: 254 AGMAFNNANLGYVHAMAHQLGG 275
>UniRef50_Q8XLZ8 Cluster: NADPH-dependent butanol dehydrogenase;
n=3; Clostridium|Rep: NADPH-dependent butanol
dehydrogenase - Clostridium perfringens
Length = 376
Score = 72.5 bits (170), Expect = 1e-11
Identities = 60/260 (23%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + ++ + ++L + + V+ ++ +P I K+ N D +A+G
Sbjct: 31 VTDPFMVKSGTIEKLTNNLKSSEVF--VFSEIVPDPPIELVVSGIEMLKDFNPDVVIALG 88
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA +D+ K V + IAIP
Sbjct: 89 GGSAIDATKA-----------IIDFSK------KLVKLNDIKFIAIPTTSGTGSEVTSFS 131
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ ++ K + + L P +A++DP TVP ++ +G D+ HALE++ +
Sbjct: 132 VITDKQKGVKYPLVSDELLPDIAILDPELVKTVPNFITADTGMDVLTHALEAYVS----- 186
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ + SD A + KY +++ N D+EAR MH A+ +AG
Sbjct: 187 --------------KNATDFSDALAEKAATLVFKYLLKAYENGNDIEAREKMHNASCLAG 232
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ A + + HG+A+ + G
Sbjct: 233 LAFNEASLGVNHGIAHVLGG 252
>UniRef50_Q2F7L2 Cluster: Alcohol dehydrogenase class IV; n=5;
Lactobacillus|Rep: Alcohol dehydrogenase class IV -
Lactobacillus reuteri
Length = 375
Score = 72.5 bits (170), Expect = 1e-11
Identities = 55/205 (26%), Positives = 84/205 (40%), Gaps = 36/205 (17%)
Query: 57 VAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
+ IGGGS MDT K + +GK K + IAIP
Sbjct: 88 IGIGGGSAMDTGKGIRFF------------GEKLGKCK-----INEYIAIPTTSGTGSEV 130
Query: 117 XXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
+ + H K I + L P AL+DP +T P+ V+ YSG D+ HALES A
Sbjct: 131 TNTAVISDTKEHRKIPILEDYLTPDCALLDPKLVMTAPKSVTAYSGMDVLTHALESLVA- 189
Query: 177 PFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAA 236
+ +N + + + + KY V + +V+AR +H A+
Sbjct: 190 ------------------KDANLFTVALSEEAIDAVTKYLVECYRHGDNVDARKIVHEAS 231
Query: 237 TMAGVGIGNAGVHLCHGLAYPIAGN 261
+AG AG+ +CH +A+ + N
Sbjct: 232 NIAGTAFNIAGLGICHSIAHQLGAN 256
>UniRef50_P0A9S2 Cluster: Lactaldehyde reductase; n=45;
Bacteria|Rep: Lactaldehyde reductase - Escherichia coli
O157:H7
Length = 383
Score = 72.5 bits (170), Expect = 1e-11
Identities = 66/258 (25%), Positives = 105/258 (40%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + V D + G+ + +YD V PT K+ + + D +AIG
Sbjct: 37 VTDKTLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS DTCKA + ++P EF D V + G N P++AIP
Sbjct: 97 GGSPQDTCKAIGIISNNP--EFAD-VRSLEGL-SPTNKPSVPILAIPTTAGTAAEVTINY 152
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ EE K P +A ID +P + +G D HA+E +
Sbjct: 153 VITDEEKRRKFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYIT----- 207
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+G+ ++D ++ + SV +GD +A M L +AG
Sbjct: 208 --------------RGAWALTDALHIKAIEIIAGALRGSV--AGDKDAGEEMALGQYVAG 251
Query: 241 VGIGNAGVHLCHGLAYPI 258
+G N G+ L HG+A+P+
Sbjct: 252 MGFSNVGLGLVHGMAHPL 269
>UniRef50_Q59104 Cluster: NAD-dependent 4-hydroxybutyrate
dehydrogenase; n=39; Bacteria|Rep: NAD-dependent
4-hydroxybutyrate dehydrogenase - Ralstonia eutropha
(Alcaligenes eutrophus)
Length = 382
Score = 72.1 bits (169), Expect = 1e-11
Identities = 64/260 (24%), Positives = 110/260 (42%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + + +D++ G+ V+D+ PT+ + A +E D VA+G
Sbjct: 35 VTDKGVVAAGVAQRAIDAM--QGLQVAVFDETPSNPTEAMVRKAAAQYREAGCDGLVAVG 92
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + + + E Y G + + + P+IA+P
Sbjct: 93 GGSSIDLAKGIAI-LATHEGELTTYATIEGGSAR-ITDKAAPLIAVPTTSGTGSEVARGA 150
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I ++ K G L P A+ DP TL +P ++ +G D H +E+F
Sbjct: 151 IIILDD-GRKLGFHSWHLLPKSAVCDPELTLGLPAGLTAATGMDAIAHCIETF------- 202
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
L PA+ NP +D A L+ + R+ + D +AR +M ++A+M G
Sbjct: 203 ---------LAPAF---NPPADGIALDGLERGWGHIERATRDGQDRDARLNM-MSASMQG 249
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
G+ H L++P+ G
Sbjct: 250 AMAFQKGLGCVHSLSHPLGG 269
>UniRef50_A3HQR7 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Pseudomonas putida (strain GB-1)
Length = 394
Score = 72.1 bits (169), Expect = 1e-11
Identities = 65/265 (24%), Positives = 106/265 (40%), Gaps = 22/265 (8%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD L + + D L G+ ++ +V P+D + +E D +A+G
Sbjct: 44 VTDQGSMRLPFVAELQDLLNDAGLACGLFGEVEPNPSDRAVLKGAAAFREWRADGIIALG 103
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDY-VNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS +D KA L + + PV +G N P+I IP
Sbjct: 104 GGSGLDGGKAVALVARQTRLPLWAFDFDKPVPEGLVAN-DFPPVICIPTTAGTGAETEST 162
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ E K + H RP ++DP TL++P ++ ++G D HALE++ F
Sbjct: 163 AMLTDSERAIKGCVWHPLARPQAVILDPELTLSLPAHLTAWTGLDAVIHALEAYFVPTF- 221
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
NP+ D A L+ L ++V D+EAR M + + +A
Sbjct: 222 ------------------NPLCDGAALQALELLWGSLEQAVEQGDDLEARGRMLIGSCLA 263
Query: 240 GVGIGNAGVHLCHGLAYPIAGNVKS 264
GV G+ L H L++ + S
Sbjct: 264 GVAF-LKGLGLVHALSHMVGATYNS 287
>UniRef50_Q8Y7U8 Cluster: PduQ protein; n=20; Firmicutes|Rep: PduQ
protein - Listeria monocytogenes
Length = 379
Score = 71.7 bits (168), Expect = 2e-11
Identities = 60/263 (22%), Positives = 108/263 (41%), Gaps = 37/263 (14%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + S + A+ D + ++ Y ++ ++ +P + I E + + +AIG
Sbjct: 31 VTDPFMVSSGMINAITDKIDQSN-TYTIFSEIIPDPPIENVVAGIEVLNECDANLMIAIG 89
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA + G+ K ++ P I IP
Sbjct: 90 GGSAIDAAKAMKFF----------------GQ-KLGTVRAMPFIVIPTTSGTGSEVTSFS 132
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ +E K + +A+ P A++D +VP ++ +G D+ HALE++ +
Sbjct: 133 VITNKEKAIKYPLITDAILPDEAILDADLVKSVPPAITADTGMDVLTHALEAYVSTK--- 189
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+N SD A +Q + Y R+ + D+EAR MH A+ +AG
Sbjct: 190 ----------------ANDYSDAMAEKVIQLVFTYLERAYKDGNDLEAREKMHNASCLAG 233
Query: 241 VGIGNAGVHLCHGLAYPIAGNVK 263
+ + L HG+A+ K
Sbjct: 234 MAFNITSLGLNHGIAHTAGAKFK 256
>UniRef50_Q3A7X4 Cluster: Alcohol dehydrogenase, class IV; n=1;
Pelobacter carbinolicus DSM 2380|Rep: Alcohol
dehydrogenase, class IV - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 383
Score = 71.3 bits (167), Expect = 2e-11
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 27/261 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAI-HFAKEGNFDSFVAI 59
+TD + + L L G+ Y+++ + P D + + H+ + G D+ VA+
Sbjct: 36 VTDQGLIDAGWVDKALYYLRNAGLQYEIFSSITSNPKDLEVTEGVAHYLRSG-CDALVAV 94
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGS DT KA ++ E DY V K + + PM+ +P
Sbjct: 95 GGGSPADTAKAIATLATN-GGELQDYEG--VNK---IRHPLPPMVIVPSTAGTGSEVSQF 148
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
I + K I +L P +A+IDP T +++ +G D HA+ES+ ++ T
Sbjct: 149 AIIVDHQRRLKMSIISKSLIPDIAIIDPDLLNTKSARLAAATGMDALSHAIESYVSLAAT 208
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
P++D+ A ++ + +SV + D A ++M +A+ A
Sbjct: 209 -------------------PLTDIHALNAIRLIFANLKQSVFDRQDAVANNNMAMASLNA 249
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
G+ NA + H + + I G
Sbjct: 250 GIAFSNAILGAGHAMTHQIDG 270
>UniRef50_A0PUM1 Cluster: Aldehyde dehydrogenase; n=2;
Mycobacterium|Rep: Aldehyde dehydrogenase -
Mycobacterium ulcerans (strain Agy99)
Length = 889
Score = 71.3 bits (167), Expect = 2e-11
Identities = 61/238 (25%), Positives = 108/238 (45%), Gaps = 28/238 (11%)
Query: 27 KVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYV 86
+V+ +V EP + + + + + D +AIGGGSV+D KA L+Y P+ + LD +
Sbjct: 521 QVFSEVTPEPDETTIRRGVALMQRVQPDLLIAIGGGSVLDAGKAMRLFYEHPE-KSLDAL 579
Query: 87 NAP-VGKGKAV-----NIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRP 140
P + K V + ++A+P + K + +L P
Sbjct: 580 TMPFLDPRKRVADYPTDRHRIQLVAVPTTSGTGSEVSPAAVLTVG--GKKETLVDYSLVP 637
Query: 141 ILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPI 200
LA++DP+ T ++P+K++ G D HALE+ +I ++P
Sbjct: 638 DLAIVDPVLTSSMPQKLTADIGIDALTHALEAIVSI-------------------FASPY 678
Query: 201 SDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
+D ++ + R+ ++ D+ AR+SM AAT+AG+ NA V H LA+ +
Sbjct: 679 TDALCAQAVRLIFDALPRAYDDPDDLSARTSMSNAATLAGLAFSNAFVGTNHTLAHAV 736
>UniRef50_Q8RBW2 Cluster: Alcohol dehydrogenase IV; n=12; cellular
organisms|Rep: Alcohol dehydrogenase IV -
Thermoanaerobacter tengcongensis
Length = 342
Score = 70.5 bits (165), Expect = 4e-11
Identities = 61/244 (25%), Positives = 105/244 (43%), Gaps = 28/244 (11%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYY 75
+L G Y +YDKV PT +A F +E + + IGGGS +DT K A L Y
Sbjct: 5 ALNTFGFKYSLYDKVGPNPTVDMIDEAAKFGRETGAKAVIGIGGGSPIDTAKSVAVLLEY 64
Query: 76 SDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
+D +A L + K + P+IAI + E + K I++
Sbjct: 65 TDKNARELYEL-------KFTPEKAAPIIAINLTHGTGTEVDRFAVATIPEKNYKPAIAY 117
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
L P+ A+ DP + + +K + D H E+ T +
Sbjct: 118 ECLYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLV------------------ 159
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
++P S + A+ ++ + +Y +VN+ ++ AR + A+ +AG+ N +HL H L
Sbjct: 160 -TSPYSILLAKEAVRLIVRYLPVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALE 218
Query: 256 YPIA 259
+P++
Sbjct: 219 HPLS 222
>UniRef50_Q0S3P9 Cluster: 1,3-propanediol dehydrogenase; n=5;
Actinomycetales|Rep: 1,3-propanediol dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 405
Score = 70.5 bits (165), Expect = 4e-11
Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP + + D L G+ V+ + P D +EG D VA+G
Sbjct: 59 VTDPGLIDAGWAAELQDQLREQGLTPVVWSALTPNPKDHEIAAGHDAYREGECDVLVALG 118
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D K + ++ LDY G +A + + P++ +P
Sbjct: 119 GGSVIDATKGIAVLAAN-GGNILDY----EGVDQATS-PIPPLVMVPSTSGTGADVSQFC 172
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I K I AL P + +IDP T+P+ ++ +G D H +E+F ++
Sbjct: 173 IVTDTRRGTKITIIGRALVPDVTVIDPRLLTTMPDWLNAATGLDALTHGIEAFVSL---- 228
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
NP++D A + + VR++ ++E+R+ M A+ AG
Sbjct: 229 ---------------AHNPLTDHHALRAVGLVTDTLVRTIEEPMEMESRAVMAQASLEAG 273
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + H +++ + G
Sbjct: 274 LAFTNAILGAAHAMSHQVGG 293
>UniRef50_Q1NU70 Cluster: Iron-containing alcohol dehydrogenase;
n=1; delta proteobacterium MLMS-1|Rep: Iron-containing
alcohol dehydrogenase - delta proteobacterium MLMS-1
Length = 388
Score = 70.1 bits (164), Expect = 6e-11
Identities = 60/233 (25%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 30 DKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAP 89
D V+ P + I + FD+ VA GGGS +D+ K N+ ++ ++ L
Sbjct: 67 DNVQANPGLSELQADIERLRGEVFDATVAFGGGSAIDSAKVLNVALAETVSD-LSLREML 125
Query: 90 VGKGKAVNIQVKPMIAIPXXXXXXXXXX-XXXIFDYEEIHAKTGISHNALRPILALIDPL 148
+ Q +P+ A+P ++D+E+ K ++ A+ P A+IDP
Sbjct: 126 ANPDRQPTTQARPLFALPTTAGTGSEVTPYSTVWDHEK-RKKHSLAGPAVFPHTAIIDPE 184
Query: 149 HTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFC 208
T +PE V+ +G D A ES T P+S+ A
Sbjct: 185 LTDALPEGVTLSTGLDAINQAAESIWNHNMT-------------------PVSEGVATRA 225
Query: 209 LQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGN 261
LQ + R +N GD AR +M + +AG+ I LCH ++YPI +
Sbjct: 226 LQLGFEALPRLLNEPGDTRARDAMAECSLLAGLAISQTRTALCHSISYPITAH 278
>UniRef50_A0W873 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Desulfuromonadales|Rep: Iron-containing alcohol
dehydrogenase - Geobacter lovleyi SZ
Length = 406
Score = 70.1 bits (164), Expect = 6e-11
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AAN 72
+L+ L G+ Y ++ P S + I ++ N D +A+GGGS +D CK AA
Sbjct: 63 ILEQLNTAGLAYVELSGIQPNPRIESVEQGIKLYRDNNCDFILAVGGGSTLDACKAIAAG 122
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
+ Y+ P + +V+A G + I P+ I + E H K
Sbjct: 123 VMYAGPVNDL--FVDAS-GLSSRI-IAAAPLATILTMAGTGSELDMGAVITVGEDHKKKV 178
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
+ H + P +++DP +T TVPE + DI CH +E +
Sbjct: 179 LLHPLVNPRFSILDPEYTYTVPEHHTMAGVADILCHLMEQY 219
>UniRef50_Q9WZS7 Cluster: NADH-dependent butanol dehydrogenase,
putative; n=5; Bacteria|Rep: NADH-dependent butanol
dehydrogenase, putative - Thermotoga maritima
Length = 395
Score = 69.7 bits (163), Expect = 7e-11
Identities = 63/252 (25%), Positives = 112/252 (44%), Gaps = 35/252 (13%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AAN 72
V+DSL ++GI + V+ P +A+ AK+ ++ + +GGGSV+D+ K AA
Sbjct: 52 VVDSLKKHGIEWVEVSGVKPNPVLSKVHEAVEVAKKEKVEAVLGVGGGSVVDSAKAVAAG 111
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
Y D +A +GK + + P+ + + E+ K G
Sbjct: 112 ALYEG------DIWDAFIGKYQIE--KALPIFDVLTISATGTEMNGNAVITNEKTKEKYG 163
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
+S AL P +++IDP T+P++ + Y D H LE +
Sbjct: 164 VSSKALYPKVSIIDPSVQFTLPKEQTVYGAVDAISHILEYY------------------- 204
Query: 193 AYQGSNP-ISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA---GVGIG-NAG 247
+ GS+P IS+ A ++T+ K R + D EAR+++ +AT+A + +G G
Sbjct: 205 -FDGSSPEISNEIAEGTIRTIMKMTERLIEKPDDYEARANLAWSATIALNGTMAVGRRGG 263
Query: 248 VHLCHGLAYPIA 259
CH + + ++
Sbjct: 264 EWACHRIEHSLS 275
>UniRef50_A1AJ15 Cluster: Putative iron-containing alcohol
dehydrogenase; n=3; Escherichia coli|Rep: Putative
iron-containing alcohol dehydrogenase - Escherichia coli
O1:K1 / APEC
Length = 372
Score = 69.7 bits (163), Expect = 7e-11
Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 19/158 (12%)
Query: 103 MIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSG 162
+IAIP I + K + L P +A++DP LT P V+ +G
Sbjct: 115 LIAIPTTSGSGSEVTSYAIISDPQNGRKYPLISGQLVPEIAILDPNLVLTAPRHVAVDTG 174
Query: 163 FDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNN 222
D+ HA+E+F + GSN SD A + +Y + N+
Sbjct: 175 MDVLTHAIEAFVST-------------------GSNDFSDALAEKAIALTWRYLPQVFND 215
Query: 223 SGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
D+ AR+ MH A+ MAG+ +AG+ L HG+A+ I G
Sbjct: 216 EKDIAARTHMHNASCMAGMAFNSAGLGLVHGMAHAIGG 253
>UniRef50_Q6Q906 Cluster: Predicted NAD-dependent 4-hydroxybutyrate
dehydrogenase; n=2; Gammaproteobacteria|Rep: Predicted
NAD-dependent 4-hydroxybutyrate dehydrogenase -
uncultured marine gamma proteobacterium EBAC20E09
Length = 377
Score = 69.7 bits (163), Expect = 7e-11
Identities = 64/260 (24%), Positives = 105/260 (40%), Gaps = 23/260 (8%)
Query: 2 TDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGG 61
TDP ++S+ M + +L N + Y++ PT+ + DA+ K N D V GG
Sbjct: 35 TDPGLSSIG-MTDKIKNLISNDFSSIYYEETPANPTENAVNDALELYKNNNCDGVVGFGG 93
Query: 62 GSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXI 121
GS +D KA L ++ + L+Y G GK + PMIAIP +
Sbjct: 94 GSSIDLAKAVAL-MANHEGSLLNYSVNEGGYGKIT--ETVPMIAIPTTSGTGSEVSVGSL 150
Query: 122 FDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
+ K + L P A+ DP TL +P ++ +G D H +E+ +
Sbjct: 151 ITMND-GRKLIYASPYLMPKAAICDPELTLGLPPVLTAGAGMDALTHCIEAILS------ 203
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
P PA G I ++ +R+ + D EAR SM +A+ +
Sbjct: 204 -PINDPPAEAVGIDGIEKI----------IKEESLIRAYKDGQDKEARWSMMMASAEGAM 252
Query: 242 GIGNAGVHLCHGLAYPIAGN 261
G+ H +++ + N
Sbjct: 253 AF-QKGLGAVHSMSHALGAN 271
>UniRef50_A6M0N3 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Clostridium beijerinckii NCIMB 8052|Rep:
Iron-containing alcohol dehydrogenase - Clostridium
beijerinckii NCIMB 8052
Length = 383
Score = 69.7 bits (163), Expect = 7e-11
Identities = 58/243 (23%), Positives = 101/243 (41%), Gaps = 36/243 (14%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
S + N V+D+V +P + K+ N +A GGGS +DT K +Y++
Sbjct: 59 SFINDSNNVSVFDEVIPDPPLNVIGKGVALIKKNNPSIVIAYGGGSAIDTAKGI-IYFAK 117
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
+ F+D VN IAIP + E K I +
Sbjct: 118 QQS-FIDKVN---------------FIAIPTTSGTGSEVTSATVVTDTETKTKHIIFDDV 161
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGS 197
+ P A++D T++VP ++ +G D+ HA+E++ A + +
Sbjct: 162 MLPDEAILDANLTVSVPADITANTGIDVLTHAIEAYVA-------------------KDA 202
Query: 198 NPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYP 257
N SD A ++ + + V+ D+ AR MH A+ +AG+ AG+ + H +A+
Sbjct: 203 NVYSDALAEKAVELVIESLVQCYKQGNDIAARKKMHEASNLAGMAFNIAGLGINHSIAHQ 262
Query: 258 IAG 260
+ G
Sbjct: 263 LGG 265
>UniRef50_A1HNQ8 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Clostridiales|Rep: Iron-containing alcohol
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 381
Score = 69.7 bits (163), Expect = 7e-11
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 24/233 (10%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
VY + P G+ + +E D +A+GGGS +D K L Y PD F + +
Sbjct: 60 VYSGIGKNPDTGAVLGGLEKMRELAPDVVIAVGGGSPIDAAKVMALMYDYPDLTFDNMLT 119
Query: 88 APVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDP 147
+ + + +Q IAIP + + + + K G+ +A P LA++D
Sbjct: 120 DELPQQRR-GVQ---FIAIPSTSGTGSEVTRAAVITFRDQNLKIGLKTDAFVPDLAILDA 175
Query: 148 LHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
T+++P + +G D HA+E + N +L + S+ AR
Sbjct: 176 DITMSMPPHIVAETGMDAVTHAVECY------------INKSL-------DDFSEALARG 216
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
+ L +Y S + E+R +H MAG+ N G+ + HG+A+ + G
Sbjct: 217 AVAGLLEYLPVSYRDK-TPESREKVHHYQCMAGLAFANVGLGVVHGIAHAVGG 268
>UniRef50_A3I686 Cluster: 1,3-propanediol dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 1,3-propanediol dehydrogenase -
Bacillus sp. B14905
Length = 378
Score = 69.3 bits (162), Expect = 1e-10
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 22/241 (9%)
Query: 21 RNGINYKVYDKVRVE---PTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
RN + + +V +E PT + KE +FD V IGGGSV+D K+
Sbjct: 51 RNCLQHYEMQQVDIEISNPTVDDLFSLFNQTKELDFDCIVGIGGGSVLDLSKSLVAIKGM 110
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
+ K N Q P I IP YE++ K I + +
Sbjct: 111 QIENHQQLLTIIEKKYYKNNEQTIPWIGIPTTSGTGSELTCWATIWYEKLGIKLSIDNPS 170
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGS 197
L A+ D T ++P ++ + D CHA E++ + S
Sbjct: 171 LYAYAAIFDHTLTTSLPVSITVSTTLDALCHATEAYWS-------------------NKS 211
Query: 198 NPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYP 257
N IS V+A+ ++ + +Y + ++E R + LA+ AG+ N CH ++YP
Sbjct: 212 NDISRVYAKEAIKRIMQYLELLIQLPSNLEYRREIALASMFAGLAFSNTRTTACHSISYP 271
Query: 258 I 258
+
Sbjct: 272 L 272
>UniRef50_Q1EZ60 Cluster: Alcohol dehydrogenase; n=3;
Clostridiales|Rep: Alcohol dehydrogenase - Clostridium
oremlandii OhILAs
Length = 387
Score = 68.9 bits (161), Expect = 1e-10
Identities = 67/261 (25%), Positives = 114/261 (43%), Gaps = 35/261 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+ D + L ++ +D L GI+ +VY VR +P + + KE D +A+G
Sbjct: 37 VVDAIMEKLGYLQKTIDLLKSAGISAEVYSDVRPDPDVKIVANGLKHYKESKADILIALG 96
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPM-IAIPXXXXXXXXXXXX 119
GGS +DT K LY+ A + + A K KP+ +AIP
Sbjct: 97 GGSAIDTAKGI-LYF----AWKFESIEASEFK--------KPLFVAIPSTSGTGSEVTDF 143
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ E+ K I + P +A++D VP+ V +G D+ HA+E++ + T
Sbjct: 144 SVVTTED--GKVCIVDEFIAPDIAILDSTCIQHVPKHVVADTGIDVLVHAMEAYVSTKAT 201
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ A A A++ ++ L+T+ R +NN+ +AR + A+ MA
Sbjct: 202 DFTDALAEKAIKLIFEN------------LETI----YRDINNT---KARDHVLNASCMA 242
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
G+ N G+ + H LA+ G
Sbjct: 243 GMAFTNTGLGINHSLAHAFGG 263
>UniRef50_A3Y9V5 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Iron-containing alcohol
dehydrogenase - Marinomonas sp. MED121
Length = 414
Score = 68.9 bits (161), Expect = 1e-10
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 57 VAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
+AIGGGSV+D KA + LDY+ VGKG + Q+ P IAIP
Sbjct: 99 IAIGGGSVLDAGKALAAMLMT-EHSLLDYLEG-VGKGLPLPDQILPFIAIPTTSGTGSEM 156
Query: 117 XXXXIFDYE-EIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
+F + K I H+ L P +D T++ P + G D F LES+ +
Sbjct: 157 TSNAVFSQVGDKGFKKSIRHDKLIPTEIWLDSRLTMSCPPLQTACCGLDAFTQLLESYLS 216
Query: 176 IPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRS-VNNSGDVEARSSMHL 234
S+ I+D A L+ + K + + N + D + R + +
Sbjct: 217 TK-------------------SSLITDTLAEKGLELIIKNLIPACTNKADDPDVRGELAI 257
Query: 235 AATMAGVGIGNAGVHLCHGLAYPIAG 260
AA ++G + NAG+ + HG+A P+ G
Sbjct: 258 AAMLSGSCLANAGLGIVHGIAGPMGG 283
>UniRef50_Q0C5T5 Cluster: 4-hydroxybutyrate dehydrogenase,
NAD-dependent; n=5; Proteobacteria|Rep:
4-hydroxybutyrate dehydrogenase, NAD-dependent -
Hyphomonas neptunium (strain ATCC 15444)
Length = 377
Score = 68.1 bits (159), Expect = 2e-10
Identities = 66/224 (29%), Positives = 95/224 (42%), Gaps = 23/224 (10%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
V+ + PT+ K A KE D +A+GGGS MD KA L S E L+
Sbjct: 60 VFAETVPNPTEAQTKVATALYKESGADGIIAVGGGSSMDHAKAIGLMASHD--EPLETYA 117
Query: 88 APVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDP 147
A +G K V ++ P+IAIP + E +T S N L P++AL DP
Sbjct: 118 AIIGGSKLVG-KIPPLIAIPTTAGTGSEVSIGMVIIMENGRKETFASPN-LIPLVALCDP 175
Query: 148 LHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
T+ +P ++ +G D H +E+ PA PA Y G+ F
Sbjct: 176 DLTIGLPAGLTAATGMDALTHCIEAILT-------PAINPPAEGIGYDGAR------RAF 222
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGI--GNAGVH 249
+ L+ R+V + D EAR M +A+ + G GVH
Sbjct: 223 GMDMLK----RAVRDGSDEEARWHMMMASYEGALAFVKGLGGVH 262
>UniRef50_A5KMY5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 387
Score = 68.1 bits (159), Expect = 2e-10
Identities = 61/256 (23%), Positives = 108/256 (42%), Gaps = 27/256 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP +AS K + SL I + V+ P + FAK+ + D+ +A+G
Sbjct: 38 ITDPFLASSEHYKKLKKSLDDAKIENFLLTNVKPNPRAEDCDEMAEFAKKNHVDALIALG 97
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXX-XX 119
GGS MD KA ++ + +++ + ++ + P+I IP
Sbjct: 98 GGSAMDQAKAVGAVVTNGKST-VEWGDT------ELDTNILPLICIPSTSGTGAEVTWCA 150
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
I D E + T + P+LA+ DP T+ +P+ ++ G D H +E++T
Sbjct: 151 VITDTERQYKMTVGDPVHMIPVLAICDPEITIGLPKSLTAACGVDALTHCIEAYTV---- 206
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
Q PI+D A + + + ++ N D EAR +M +A+T+
Sbjct: 207 ---------------QLHQPITDALALKGISMIAENLEKAYENGEDREARRNMMIASTIG 251
Query: 240 GVGIGNAGVHLCHGLA 255
G+ ++ V H A
Sbjct: 252 GMAFISSNVGAVHAFA 267
>UniRef50_A4AC61 Cluster: Alcohol dehydrogenase, iron-containing;
n=3; unclassified Gammaproteobacteria|Rep: Alcohol
dehydrogenase, iron-containing - Congregibacter
litoralis KT71
Length = 397
Score = 68.1 bits (159), Expect = 2e-10
Identities = 66/261 (25%), Positives = 104/261 (39%), Gaps = 27/261 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + L+ + ++ YD V+ +PT + K+ D+ +AIG
Sbjct: 52 VTDTVLRDLGIVDKALEGFKDSDVDIAFYDGVQPDPTFDQGAAGLAILKDHGSDAVLAIG 111
Query: 61 GGSVMDTCK-AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGS +D K A SD D D+ +G K V +V P+ AIP
Sbjct: 112 GGSSIDCAKLIAATATSDEDPR--DW----IGFAK-VKHEVMPLFAIPTTAGTGSEATMG 164
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ H K IS L +DP + +P ++ +G D HA+E++ I
Sbjct: 165 AVISDSATHEKGVISGAGLGMGATALDPDLQMGMPPAITAATGMDALTHAIEAY--ICRW 222
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+RG N A ++ + R+ D EAR SM LA+ A
Sbjct: 223 DRGTRKEN-----------------AERAIRIIFANLERAYTQGDDAEARESMALASYYA 265
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
G+ I V H +A+ + G
Sbjct: 266 GIAINQVNVGTVHAIAHQLGG 286
>UniRef50_A6LP70 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Thermosipho melanesiensis BI429|Rep:
Iron-containing alcohol dehydrogenase - Thermosipho
melanesiensis BI429
Length = 361
Score = 67.7 bits (158), Expect = 3e-10
Identities = 61/253 (24%), Positives = 109/253 (43%), Gaps = 36/253 (14%)
Query: 8 SLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIH-FAKEGNFDSFVAIGGGSVMD 66
SL + +L+ L + Y+++D+ P + I + K N+D V +GGGS MD
Sbjct: 42 SLDELLKILNKLNKK---YEIFDETLENPPKEMINNIIERYGK--NWDVIVGLGGGSPMD 96
Query: 67 TCKA-ANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYE 125
T KA A L ++ E L N K ++ IP +
Sbjct: 97 TAKAVAVLCKNNISVEELYDSNKYNSAAK--------ILCIPTTSGTGSEVTQYSVLTIN 148
Query: 126 EIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAP 185
+ K G H+ + P +A+++P +TLT+ ++++ + D HA+E+F ++
Sbjct: 149 NV--KKGFKHDVIFPDVAILEPKYTLTLNKELTVSTALDALSHAIEAFLSL--------- 197
Query: 186 ANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGN 245
+N SD++A ++ + V + G+ E R + LA+ AG+ IG
Sbjct: 198 ----------RANSFSDLYALKAIEIISLNLNNLVKDLGNYELRKKIMLASLYAGISIGI 247
Query: 246 AGVHLCHGLAYPI 258
G + H L Y +
Sbjct: 248 TGTTIAHSLGYSL 260
>UniRef50_A5ZM66 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 383
Score = 67.7 bits (158), Expect = 3e-10
Identities = 59/258 (22%), Positives = 104/258 (40%), Gaps = 36/258 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TDP V + + + L + GI Y ++ V + D + ++ VA+G
Sbjct: 31 ITDPFVVQSKMIDLITEPLAKGGIEYDIFSNVVPDAPVDKIADGVKKFLSYQPEAVVAVG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D+ KA EF +N GK +IA+P
Sbjct: 91 GGSAIDSSKAIR--------EFALKIN---NYGKV------GLIAVPTTSGTGSEVTSFA 133
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + E K + L A++D +VP ++ +G D+F HALES+ +
Sbjct: 134 VVNDTEAKVKYPLVSPDLTADEAILDAELVKSVPPAITADTGMDVFTHALESYVST---- 189
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
G N S A ++ + +R+ + D+ AR MH+A+ +AG
Sbjct: 190 ---------------GHNEFSAALAEKAMEICGVFLLRAYLDGSDMHARQKMHVASCLAG 234
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ AG+ + H +A+ +
Sbjct: 235 LSFNTAGLGITHSMAHQL 252
>UniRef50_A5N1L2 Cluster: Predicted iron containing alcohol
dehydrogenase; n=5; Clostridium kluyveri DSM 555|Rep:
Predicted iron containing alcohol dehydrogenase -
Clostridium kluyveri DSM 555
Length = 390
Score = 67.7 bits (158), Expect = 3e-10
Identities = 66/265 (24%), Positives = 115/265 (43%), Gaps = 32/265 (12%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSF-KDAI-HFAKEGN-----F 53
+TD N+ L ++ V + L I+Y ++D + SF +DA+ +F K N +
Sbjct: 38 VTDKNIIRLGHVEIVEEILKDLFISYDIFDGILHPDCTISFVEDALTYFKKRLNILKKDY 97
Query: 54 DSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXX 113
+++GGG+ D K + ++ + DY G K + P+I+I
Sbjct: 98 HFIISVGGGTNHDCAKGIAIVATN-GGDIEDYE----GYEKMTKPSL-PVISINTTSGSG 151
Query: 114 XXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
I + K I+ + PI+++ D T+P K++ SG D+ H++E F
Sbjct: 152 SEVTNITIMRDDSRGVKMIIADPKMMPIISVNDLRFMETMPPKITANSGIDVLTHSIEGF 211
Query: 174 TAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMH 233
AI ++PI+D A L+ + Y R+ N D+EAR M
Sbjct: 212 VAIE-------------------ASPITDTLAINALKLVFGYLRRAYKNGNDMEAREKMM 252
Query: 234 LAATMAGVGIGNAGVHLCHGLAYPI 258
A M G+ + NAG+ H +++ I
Sbjct: 253 FAGVMGGMVLNNAGLGYVHSMSHQI 277
>UniRef50_Q8KDU3 Cluster: Alcohol dehydrogenase, iron-containing;
n=8; Chlorobiaceae|Rep: Alcohol dehydrogenase,
iron-containing - Chlorobium tepidum
Length = 383
Score = 67.3 bits (157), Expect = 4e-10
Identities = 69/256 (26%), Positives = 110/256 (42%), Gaps = 29/256 (11%)
Query: 10 SPMKA-VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTC 68
SP+ + +L+ L G+ + R EP+ +A ++ F+ VAIGGGS +D
Sbjct: 37 SPVASRMLNELRHAGMEVACLEVER-EPSPELINEAAALGRQKPFEVVVAIGGGSALDAG 95
Query: 69 KA--ANLYYSDPDAEFL-DYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYE 125
KA A L DP F+ D G+ V P IA+P +
Sbjct: 96 KAISAMLLQRDPVERFIEDQPGFTPHDGRKV-----PFIAVPTTSGTGTEATSNAVISRI 150
Query: 126 EIHA-KTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPA 184
K + H A P +A+IDP +++P +V+ +G D F LE++ + PF
Sbjct: 151 GPGGFKRSLRHPAFVPDVAIIDPELMVSLPREVTVSTGMDAFTQLLEAYLS-PFAS---- 205
Query: 185 PANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIG 244
AY + S + F + + V S + + V R+ M AA M+G+ +
Sbjct: 206 --------AYTDALCCSGL-EHFA----RSFAVASGDGAASVAVRADMAYAALMSGIVLA 252
Query: 245 NAGVHLCHGLAYPIAG 260
NAG+ + HG A + G
Sbjct: 253 NAGLGIVHGFASSVGG 268
>UniRef50_Q7R169 Cluster: GLP_447_53872_52544; n=2; Giardia
intestinalis|Rep: GLP_447_53872_52544 - Giardia lamblia
ATCC 50803
Length = 442
Score = 66.9 bits (156), Expect = 5e-10
Identities = 60/251 (23%), Positives = 100/251 (39%), Gaps = 22/251 (8%)
Query: 8 SLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDT 67
SLS +K +L S + I ++++V P+ + A D + +GGGS MD
Sbjct: 88 SLSKLKDILAS---HEIESYLFNEVEPNPSTVTVTKAARQVSGKQVDFVIGLGGGSAMDA 144
Query: 68 CKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEI 127
KA +Y + + G A++ K +I I I
Sbjct: 145 AKAIAVYLVNKE-----------GIKVAISESPKDVICISTAAGTASEVTPYAILTDHIK 193
Query: 128 HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPAN 187
K I N + P ++L+DP + L +P + DI CHA+ES + TE
Sbjct: 194 QTKISIP-NLVFPKISLVDPCYQLYLPTSQTLSMFLDILCHAVESMLTVKTTEL------ 246
Query: 188 PALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAG 247
+++ + + + W + + K + + E R M LA+ AG+ I G
Sbjct: 247 -SVKASVESLKHLQICWHFYLKPAIMKTTFTDLTDPEMTEFRDEMTLASCYAGIAITIGG 305
Query: 248 VHLCHGLAYPI 258
+ HGL+Y I
Sbjct: 306 TSIAHGLSYKI 316
>UniRef50_Q5L3J5 Cluster: Alcohol dehydrogenase; n=1; Geobacillus
kaustophilus|Rep: Alcohol dehydrogenase - Geobacillus
kaustophilus
Length = 403
Score = 66.5 bits (155), Expect = 7e-10
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 25/233 (10%)
Query: 14 AVLDSLTRNGINYK---VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA 70
A L LT +G+ + ++ +R + +A+ +A+ D+ +A+GGGSV+DT K
Sbjct: 53 ASLFDLTTHGVGPELVGIFLDIRQDAESECVNEAVRYARAVGADALLAVGGGSVLDTAKG 112
Query: 71 ANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPM--IAIPXXXXXXXXXXXXXIFDYEEIH 128
+ + + + Q P+ IAIP + EE+
Sbjct: 113 VKYALFKGLRDIKEAIPGGLRYESFPQAQFMPIPHIAIPTTAGTGSEVSPIAVIYNEELR 172
Query: 129 AKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANP 188
KT I + + +A++DP T+ +P KV+ ++G D HA+E A A+P
Sbjct: 173 LKTNIINPFINADVAVLDPDLTVGLPPKVTAFTGMDALTHAIE------------ALASP 220
Query: 189 ALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGV 241
+ ++D A ++ ++ Y +V + GD+ AR M L A++ G+
Sbjct: 221 M-------ATALTDACALQAIRLIRDYLPEAVRDGGDIRARLEM-LHASLLGI 265
>UniRef50_A6PLH8 Cluster: Iron-containing alcohol dehydrogenase;
n=9; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Victivallis vadensis ATCC BAA-548
Length = 400
Score = 66.1 bits (154), Expect = 9e-10
Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 28/244 (11%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDT--CKAANLYY 75
+L GI Y VY++V PT G A+ ++ ++ + IGGGS +D C AA + Y
Sbjct: 63 ALKAAGITYAVYNEVTPNPTTGQVDTAVLVGRDIKAEAVIGIGGGSALDAGKCVAAMMKY 122
Query: 76 SDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
+ A A + G+ P +A+ + + K I+
Sbjct: 123 PNHKA-------AQLASGELEPADALPFLAVNLTHGTGSEVNRFAVITDTDRDFKPVIAA 175
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
+ L P A+ DP ++ +K + + D H +E+ T+ +
Sbjct: 176 DCLYPAWAIDDPALMTSLSQKQTRFVSIDAVNHVVEAATS-------------------K 216
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
+NP++ + ++ + KY ++ + D+ AR + AA +AG N+ +H H L
Sbjct: 217 AANPLAIMLGAETIRLVAKYLPSALKDPKDLYARYFLAYAAMIAGTAFDNSLLHFTHALE 276
Query: 256 YPIA 259
+P++
Sbjct: 277 HPLS 280
>UniRef50_A7TAX8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 375
Score = 66.1 bits (154), Expect = 9e-10
Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 18/130 (13%)
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
G+ L P LAL+D TL +P V+ +G D HA+E++T+ AL+
Sbjct: 2 GVVSPLLLPDLALLDAELTLGLPPAVTAATGIDAMVHAIEAYTS-------------ALK 48
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLC 251
NP+SD+ AR L+ L V+N G+ EAR +M L + +AG NA V
Sbjct: 49 -----KNPLSDLLAREALRLLAANLDEVVHNGGNREARQAMLLGSCLAGQAFANAPVAAV 103
Query: 252 HGLAYPIAGN 261
H LAYP+ G+
Sbjct: 104 HALAYPLGGH 113
>UniRef50_Q31J66 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Thiomicrospira crunogena XCL-2|Rep: Iron-containing
alcohol dehydrogenase - Thiomicrospira crunogena (strain
XCL-2)
Length = 395
Score = 65.7 bits (153), Expect = 1e-09
Identities = 69/246 (28%), Positives = 101/246 (41%), Gaps = 24/246 (9%)
Query: 14 AVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA-AN 72
A++ L + I V+ V EP+ + D I A N D+ + IGGGSV+D KA A
Sbjct: 52 ALITQLQQANIRVNVF-VVSGEPSP-NLVDEIVKASPNNADAVIGIGGGSVLDAAKAVAG 109
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
L S +DY+ VGKG + P IA+P + K
Sbjct: 110 LIPS--QTSVMDYLEG-VGKGLKLAGNTLPFIAMPTTAGTGSETTKNAVLS-RLGEFKKS 165
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
+ L +DP T P +V +G D F LES+T + P AL
Sbjct: 166 FRDDKLLAKEVWLDPSFLPTCPHEVLYSTGMDAFTQLLESYTTLKAN-----PITDAL-- 218
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
A+QG + + + S N ++ LAA+++G+ + NAG+ H
Sbjct: 219 AWQGMTLFNGAFKA----------INSDNFEQQKTGYGNLMLAASLSGITLANAGLGAVH 268
Query: 253 GLAYPI 258
GLA PI
Sbjct: 269 GLAGPI 274
>UniRef50_Q1JXM5 Cluster: Iron-containing alcohol dehydrogenase;
n=5; Deltaproteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Desulfuromonas acetoxidans DSM 684
Length = 383
Score = 65.7 bits (153), Expect = 1e-09
Identities = 58/245 (23%), Positives = 104/245 (42%), Gaps = 22/245 (8%)
Query: 16 LDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYY 75
++ L GI+ V++ V +P+ + + N D V +GG S +D KA ++Y
Sbjct: 47 INLLQEAGISSVVFEGVEADPSVETVMRGVELCNRENPDLIVGLGGCSAIDAAKAMWVFY 106
Query: 76 SDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
PDA F + + AP K + + + +AIP + K +
Sbjct: 107 EYPDATFGE-ITAPF-TIKPLRNKAR-FVAIPSTSGTGTEATCVAVITDTAKGIKHPLVS 163
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
+ P +A++D ++P ++ +G D H +E+ A AL Y
Sbjct: 164 YEICPDIAIVDGELAKSMPADITANTGMDALSHDVEAVVA-------------ALASTY- 209
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
SD A ++T+ ++ N D+ AR +MH A+ MAG+ NA + + H ++
Sbjct: 210 -----SDTMALRSIRTIFDTLPQACANGEDMAARQAMHDASCMAGMAFSNAILGIIHSIS 264
Query: 256 YPIAG 260
+ I G
Sbjct: 265 HQIGG 269
>UniRef50_A3HAZ3 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Pseudomonas putida GB-1|Rep: Iron-containing
alcohol dehydrogenase - Pseudomonas putida (strain GB-1)
Length = 401
Score = 65.7 bits (153), Expect = 1e-09
Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 27/233 (11%)
Query: 28 VYDKVRVEPTDGSFKDAIH---FAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLD 84
V D V+ P D ++ +H +A+ G+ D+ +A+GGGS +DT KA L F +
Sbjct: 96 VIDNVQPNP-DVAWLRGVHEAFWAQHGDCDTVLALGGGSAIDTAKA--LIVGTASGRFDE 152
Query: 85 YVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXX-XXIFDYEEIHAKTGISHNALRPILA 143
++ V + K ++A P ++D + K + P +A
Sbjct: 153 LLDLLASGKPFVPPRHKTLVAAPTTAGTGSEVTPWATLWDAGQ-QKKYSLHLPCTWPSVA 211
Query: 144 LIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDV 203
LIDP L+VP V+ +G D HALES +NP+SD
Sbjct: 212 LIDPQLMLSVPAAVTVSTGLDALSHALESIW-------------------NHNANPLSDT 252
Query: 204 WARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAY 256
+A ++ + R + G+ E R+ M LAA AG+ N L H ++Y
Sbjct: 253 FALSAIEDILDCLPRLQQDLGNPELRARMALAALKAGLAFSNTKTALAHSISY 305
>UniRef50_A6GSB4 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Limnobacter sp. MED105|Rep: Iron-containing alcohol
dehydrogenase - Limnobacter sp. MED105
Length = 404
Score = 64.9 bits (151), Expect = 2e-09
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 29/258 (11%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + + L G+ Y VYD V PT + E + +A+G
Sbjct: 56 VTDAVLVKLGVLDKMKAELETQGVKYVVYDGVEPNPTVEQIEAGYRMLMENGCQAILAVG 115
Query: 61 GGSVMDTCK--AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXX 118
GGS +D K A + P + + V KG + P+ A+P
Sbjct: 116 GGSPIDAAKMIGARAKNNKPVLKLTGLLR--VHKG------MIPLFAVPTTAGTGAEVTI 167
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ K L P A +D +P +++ +G D HA+E+F +
Sbjct: 168 AAVVSDTVNKRKVAAMDIRLLPTAAALDGSLMTGLPAHITSATGMDALTHAVEAFVSRNA 227
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
T + +D A Q + K+ +V + G++EAR M A+ +
Sbjct: 228 TRK-------------------TDEKALEATQLIMKHLETAVADGGNLEARQKMARASHL 268
Query: 239 AGVGIGNAGVHLCHGLAY 256
AG+ AGV HG+A+
Sbjct: 269 AGIAFTQAGVGYVHGIAH 286
>UniRef50_A4RY11 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 413
Score = 64.9 bits (151), Expect = 2e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 28/233 (12%)
Query: 33 RVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDT--CKAANLYYSDP--DAEFLDYVNA 88
R EPT S A A E + +AIGGG+ +DT C AA + P + + +Y+
Sbjct: 83 RGEPTVASALSATEAAVESDCGIVIAIGGGTPVDTAKCVAAMITNRRPGENPDLYEYLEV 142
Query: 89 PVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPL 148
VG+ + + + P IAIP + + + K + H + P +A+IDP+
Sbjct: 143 -VGRAQPLTKRTAPFIAIPTTAGPGAEVAKNSVLEAGD--RKVSMRHPFMLPSVAVIDPM 199
Query: 149 HTLTVPEKVSNYSGFDIFCHALESFT-AIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
TL++P V+ +G D +E + +P NP+ D +
Sbjct: 200 LTLSLPRAVTVDTGLDALTQCIEPYVCCVP--------------------NPMIDAISMA 239
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
+ R V++ D++AR M L + G+ + NA + HG + + G
Sbjct: 240 GIVAGAGALRRVVDDGSDIDAREQMCLCSYYGGLSLANAKLGAVHGFSGTLGG 292
>UniRef50_Q894T1 Cluster: Alcohol dehydrogenase 2; n=5;
Clostridium|Rep: Alcohol dehydrogenase 2 - Clostridium
tetani
Length = 382
Score = 64.1 bits (149), Expect = 4e-09
Identities = 53/235 (22%), Positives = 98/235 (41%), Gaps = 34/235 (14%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
+Y + +P+ I + N +A+GGGS +D KA Y
Sbjct: 58 IYSDIVPDPSVEVIASGIQKLQSCNAQIIIALGGGSSIDGAKAIKEY------------- 104
Query: 88 APVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDP 147
+ GK +NI+ AIP + ++ K I+ +L P +A++DP
Sbjct: 105 SKKVTGKTINIE--EFYAIPTTSGTGSEVTEYAVITNKQEGLKYAITDKSLLPTVAILDP 162
Query: 148 LHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
+VP+ ++ +G D+ HALE++ + T+ A A A A+
Sbjct: 163 QLVKSVPKAITADTGMDVITHALEAYVSKNATDFSDALAEKAFTLAF------------- 209
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGNV 262
++ ++ + D+ AR +H A+ +AG+ AG+ + H LA+ + G +
Sbjct: 210 ------RFLPQAYADGEDIIAREKLHNASCLAGMAFNAAGLGITHSLAHAVGGKL 258
>UniRef50_Q97N98 Cluster: Alcohol dehydrogenase, iron-containing;
n=16; Firmicutes|Rep: Alcohol dehydrogenase,
iron-containing - Streptococcus pneumoniae
Length = 383
Score = 63.7 bits (148), Expect = 5e-09
Identities = 57/258 (22%), Positives = 105/258 (40%), Gaps = 25/258 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + L L GI Y ++ V PT + D + +E D +++G
Sbjct: 35 VTDKYIEGSDILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLG 94
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS D ++ ++ + DY K + P++AI
Sbjct: 95 GGSPQDAASCISIMATN-GGKPQDYEGLHKSAKKGL-----PVVAINTTAGTSAEITINY 148
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ EE K + ++++ DP L+ P+ ++ +G D HA+E+
Sbjct: 149 VITDEERKVKMVMVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVT----- 203
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P AY + +S + A ++ +++Y R+V N D+EAR M A + G
Sbjct: 204 --PG--------AYDVTKKLS-IGA---IELIKEYLPRAVENGHDIEAREGMVNAIFLGG 249
Query: 241 VGIGNAGVHLCHGLAYPI 258
+ NAG+ H +A+ +
Sbjct: 250 MSFNNAGLGYVHSMAHQL 267
>UniRef50_A6PCI9 Cluster: Iron-containing alcohol dehydrogenase;
n=8; Gammaproteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Shewanella sediminis HAW-EB3
Length = 410
Score = 63.3 bits (147), Expect = 6e-09
Identities = 54/256 (21%), Positives = 102/256 (39%), Gaps = 25/256 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + + LT N + + VYD V +P + + K D+ +A+G
Sbjct: 63 VTDTVLIKLGLLDNIQQKLTDNNVQFAVYDGVLPDPNYAQVESGLALYKSSGCDAILAVG 122
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K ++ + G K P+ AIP
Sbjct: 123 GGSPIDAAKVIAARVNNHRE-----IKKLTGLFKVWKAPA-PLFAIPTTAGTGSEVTIAA 176
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ H KT + L P++A +D +P V++ +G D HA+E+F ++
Sbjct: 177 VVSDPVTHKKTPLIDPKLVPMMASLDASLMTGLPAHVTSATGMDALTHAVEAFISM---- 232
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
++ +D +A + + + V+N ++EAR +M +A+ AG
Sbjct: 233 ---------------NASSDTDAYAIAATKLISQNLSIVVHNGTNLEARQNMAMASYYAG 277
Query: 241 VGIGNAGVHLCHGLAY 256
+ A + H +++
Sbjct: 278 LAFTKASLGYVHAISH 293
>UniRef50_Q30VG9 Cluster: Alcohol dehydrogenase, iron-containing;
n=4; Deltaproteobacteria|Rep: Alcohol dehydrogenase,
iron-containing - Desulfovibrio desulfuricans (strain
G20)
Length = 380
Score = 62.5 bits (145), Expect = 1e-08
Identities = 57/260 (21%), Positives = 105/260 (40%), Gaps = 26/260 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++DP + ++ V+D L+ + + Y+ V P D + E D + +G
Sbjct: 36 VSDPGLEKAGWVQHVIDILSEDRLECVYYNDVDSNPRDWQVHEGARLYTEERADLIIGLG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K S+ DY A + + PMI IP
Sbjct: 96 GGSPIDAAKGIATIASN-GGRIHDYEGA-----NRIMRPLPPMIFIPTTAGSGSDISQYC 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I E K I +L P +++IDP LT ++ S D HA+ES+ +
Sbjct: 150 IITDVERQLKMSIISRSLVPNVSIIDPSLLLTKTVELILASAIDALAHAVESYVS----- 204
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ ++P ++ A + ++ + + + + + + A + +A+T AG
Sbjct: 205 --------------RLASPFTETQALYAIRLIMEN-LETAARTRNPAALEKLSIASTAAG 249
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NAG+ + H LA+ + G
Sbjct: 250 MSFSNAGLGIGHALAHSLGG 269
>UniRef50_A4C4S1 Cluster: Alcohol dehydrogenase; n=1;
Pseudoalteromonas tunicata D2|Rep: Alcohol dehydrogenase
- Pseudoalteromonas tunicata D2
Length = 398
Score = 62.5 bits (145), Expect = 1e-08
Identities = 43/176 (24%), Positives = 74/176 (42%), Gaps = 5/176 (2%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + L + + D+L + Y V+ V PT + + + F + D+ +AIG
Sbjct: 51 VTDQVLKQLLVINQITDALDNMALEYVVFADVSPNPTIHNVEQGLVFYQSHQCDAIMAIG 110
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D K P+ + G K + ++ P+ AIP
Sbjct: 111 GGSVIDCAKLIGARAVKPNKT----LKQLKGLFKILK-KLPPLYAIPTTAGTGSETTVAA 165
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
+ H K ++ L P AL+ P T+ +P ++ + D HA+E+F I
Sbjct: 166 VVSDTTSHQKYAVTDLVLMPKAALLYPPLTVNLPSSLTATTAMDALTHAIEAFIGI 221
>UniRef50_A4J4M6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Desulfotomaculum reducens MI-1|Rep: Iron-containing
alcohol dehydrogenase - Desulfotomaculum reducens MI-1
Length = 380
Score = 62.1 bits (144), Expect = 1e-08
Identities = 61/261 (23%), Positives = 107/261 (40%), Gaps = 27/261 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD V + ++ VL SL NG+ V+ V P D ++ + DS +A+G
Sbjct: 36 VTDRGVHASGWLERVLGSLNDNGLECIVWKDVSPNPKDYEIYCGVNKYIDNKCDSLLAVG 95
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D KA L S+ + DY ++ + P++A+
Sbjct: 96 GGSPIDAAKAVALLVSN-GGKLSDYEEI-----DSITRPLPPIVAVTTTAGSGSEVSQFS 149
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
I K I +L P +++ DP T+ + YSG + HA+E++ +
Sbjct: 150 IIVNAPEKRKMTIVSKSLIPYISIHDPQLLETLNNQAMIYSGVHVLTHAIEAYVS----- 204
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSV-NNSGDVEARSSMHLAATMA 239
+G+ P++D++A + TL +R V + SM +A A
Sbjct: 205 --------------KGATPMTDLFALNAI-TLAADSLRLVKGGKRSTDLNQSMAMANLNA 249
Query: 240 GVGIGNAGVHLCHGLAYPIAG 260
G+ NA + H + + I+G
Sbjct: 250 GLAFSNAILGAVHAITHQISG 270
>UniRef50_A1WPM6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
Iron-containing alcohol dehydrogenase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 399
Score = 62.1 bits (144), Expect = 1e-08
Identities = 66/259 (25%), Positives = 104/259 (40%), Gaps = 26/259 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D + + ++ L L G+ ++D V PT + A+ D VA+G
Sbjct: 50 VSDAGLVAAGLVEPHLARLRDAGLVPCLFDGVEANPTLDNVAQALDLWHSQACDGVVALG 109
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQ-VKPMIAIPXXXXXXXXXXXX 119
GGSV+D CK L DA V + +G A+ + + P AIP
Sbjct: 110 GGSVIDVCKVL-LARLCSDAP----VEQVLREGDALLCRPIPPFAAIPTTAGTGSESTTA 164
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ + K + A RP +DPL TL+VP V+ +GFD HAL + T
Sbjct: 165 ALVKDAQ-GRKHVLRSRACRPQWVALDPLLTLSVPPAVTACTGFDTVMHALGAAT----- 218
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ +NP+ + A + + ++ARS M LA+ +A
Sbjct: 219 --------------NRATNPVGEALALQAMVLSFHALPLVIAQPDALQARSDMLLASYLA 264
Query: 240 GVGIGNAGVHLCHGLAYPI 258
GV + G HGL P+
Sbjct: 265 GVAMSLRGTDGIHGLCTPL 283
>UniRef50_A0KHX0 Cluster: Alcohol dehydrogenase, iron-containing;
n=4; Gammaproteobacteria|Rep: Alcohol dehydrogenase,
iron-containing - Aeromonas hydrophila subsp. hydrophila
(strain ATCC 7966 / NCIB 9240)
Length = 384
Score = 62.1 bits (144), Expect = 1e-08
Identities = 59/260 (22%), Positives = 103/260 (39%), Gaps = 35/260 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + + V L + GI + +D V +P + + D +A+G
Sbjct: 31 VTDQMMVKVGLADRVTQILRQRGIPFLCWDDVVADPDITTVVRGMKLMDGCYPDLVIALG 90
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGSV+D KA L +G+ + +AIP
Sbjct: 91 GGSVIDAAKAVMFA--------LAQTRPHLGRERPC------FVAIPTTSGTGSEVTSFS 136
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ K + +L P +A++DP +VP ++ +G D+ CHALE++ +
Sbjct: 137 VVKARS--EKLVLVDPSLLPDIAILDPSLVASVPPAITADTGMDVLCHALEAYVS----- 189
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
+ ++ SD A +Q + +Y + D+ AR MH A+ MAG
Sbjct: 190 --------------RAASDFSDALAEKVVQQVFRYLPACWRDGHDLLAREKMHNASCMAG 235
Query: 241 VGIGNAGVHLCHGLAYPIAG 260
+ NA + + H LA+ + G
Sbjct: 236 MAFTNASLGITHSLAHALGG 255
>UniRef50_A4XJK8 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Iron-containing alcohol dehydrogenase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 364
Score = 61.7 bits (143), Expect = 2e-08
Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 7/173 (4%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+T P+ ++ V L I Y +Y K+ P+ + + A+E + D + IG
Sbjct: 33 VTSPSSLMNGSLEDVTTVLNELSIEYSIYSKIAQNPSVEQIDEVSNLAREFSPDFIIGIG 92
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D+ KA + ++ + + D ++ K P++AIP
Sbjct: 93 GGSPLDSSKAVAVLCAEKNLKAPDLFDSKFEK-------CLPIVAIPTTCGTGSEVTPYS 145
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
I + I K + + P LA++D + LT+P V + FD H +E +
Sbjct: 146 ILTLKTIENKKSFASELIFPKLAIVDYKYLLTLPFNVIVNTIFDALSHVIEGY 198
>UniRef50_A1B5B0 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Paracoccus denitrificans (strain Pd
1222)
Length = 377
Score = 61.7 bits (143), Expect = 2e-08
Identities = 64/257 (24%), Positives = 97/257 (37%), Gaps = 25/257 (9%)
Query: 6 VASLSPMKA--VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGS 63
V +P +A +LD+L G EPT + A+ AK D A+GGG+
Sbjct: 36 VHGANPARAGWLLDALRAEGAEVLAI-ACGAEPTLPMLEAALAEAKGFGADWVAALGGGA 94
Query: 64 VMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFD 123
V+D KA P +D++ VG+G + P +A+P +
Sbjct: 95 VLDLGKALAALIPAPGG-IMDHLEV-VGRGLPLAAPPLPYVALPTTAGTGAEATRNAVIG 152
Query: 124 YEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGP 183
+ K I + P LA++DP T P V+ SG D +E + + T
Sbjct: 153 LPDHGRKVSIRDERMLPRLAIVDPALTDHCPRAVTLASGLDALAQVIEPYVSARATPFTD 212
Query: 184 APANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGI 243
A PA+ P L L + + + D AR M + G+ +
Sbjct: 213 ALTRPAIGPG---------------LAALVR-----LMQAEDAGARDRMAWVSLSGGIAL 252
Query: 244 GNAGVHLCHGLAYPIAG 260
N G+ HGLA I G
Sbjct: 253 ANGGLGAVHGLAGVIGG 269
>UniRef50_Q53062 Cluster: NDMA-dependent methanol dehydrogenase;
n=9; Actinomycetales|Rep: NDMA-dependent methanol
dehydrogenase - Rhodococcus erythropolis
Length = 423
Score = 61.7 bits (143), Expect = 2e-08
Identities = 59/252 (23%), Positives = 101/252 (40%), Gaps = 28/252 (11%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
++ ++ + G+ +YDKV P D + +A ++ DS ++IGGGS D K A
Sbjct: 56 IEELVGKIEYQGVEVVLYDKVESNPKDYNVMEAAALYQKEKCDSIISIGGGSSHDAAKGA 115
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIF----DYEEI 127
+ + +N G K+ N + P IA+ + D
Sbjct: 116 RVVIAHDGRN----INEFEGFAKSTNKENPPHIAVSTTAGTGSETSWAYVITDTSDMNNP 171
Query: 128 HAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPAN 187
H G A LA+ DPL T P+ + Y GFD+ H E PF R
Sbjct: 172 HKWVGFD-EATIVTLAIDDPLLYYTCPQHFTAYCGFDVLAHGSE-----PFVSR--LDFA 223
Query: 188 PALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAG 247
P+L N I + ++ + K +V +++AR M A +AG + G
Sbjct: 224 PSL------GNAI------YSVELVAKNLREAVFEPRNLKAREGMMNAQYIAGQAFNSGG 271
Query: 248 VHLCHGLAYPIA 259
+ + H +++ ++
Sbjct: 272 LGIVHSISHAVS 283
>UniRef50_Q839H5 Cluster: NADH-dependent butanol dehydrogenase,
putative; n=4; Firmicutes|Rep: NADH-dependent butanol
dehydrogenase, putative - Enterococcus faecalis
(Streptococcus faecalis)
Length = 395
Score = 61.3 bits (142), Expect = 3e-08
Identities = 57/249 (22%), Positives = 104/249 (41%), Gaps = 28/249 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA-ANL 73
+ D +NG V P + + I KE D +A+GGGS +D KA A
Sbjct: 51 ITDLAQKNGHTLIELSGVEPNPRIETVRKGIELCKENQVDVILAVGGGSTIDCSKAIAAG 110
Query: 74 YYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
+YS+ D + + K P++ I + E + K G
Sbjct: 111 FYSEED------IWTVIAARKGYTGPALPIVTILTLAATGSEMNAGAVISNLETNQKLGF 164
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPA 193
+ P ++ +DP +T TVP+ + DIF H +E++ +I
Sbjct: 165 GGPNMIPKVSFLDPTNTFTVPQNQTAAGSADIFSHLIENYFSIS---------------- 208
Query: 194 YQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA--GV-GIGNAGVHL 250
G++ + D + ++T+ K ++ N D +AR+++ A+++A G+ G G GV
Sbjct: 209 -TGAD-VQDFVSEGLMRTVIKNCPIALENPEDYDARANLMWASSLALNGLTGRGKQGVWS 266
Query: 251 CHGLAYPIA 259
CH + + ++
Sbjct: 267 CHPMEHELS 275
>UniRef50_A7HJ36 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Fervidobacterium nodosum Rt17-B1|Rep:
Iron-containing alcohol dehydrogenase - Fervidobacterium
nodosum Rt17-B1
Length = 359
Score = 61.3 bits (142), Expect = 3e-08
Identities = 53/245 (21%), Positives = 101/245 (41%), Gaps = 31/245 (12%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
++ +LD L G N ++YD+ P K K + D + +GGGS MD KA
Sbjct: 44 LEDLLDVL--EGKNVQIYDETPENPPTDIIKPIAQ--KYYDVDVVIGLGGGSPMDAAKAV 99
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
+ +P D + K + K ++ IP + + K
Sbjct: 100 AVLIENPHLSAEDLYD------KTKYSRAKTIVCIPTTAGTGSEVTQYSVLTFNG--KKR 151
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
G SH+ + P ++ +D +T+T+ + ++ + D HA+E + ++
Sbjct: 152 GFSHDCVFPKVSFVDYKYTMTLGKNLTISTALDALSHAMEGYISLK-------------- 197
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLC 251
S P SD A ++ +++Y + +++ + R + A+T+AG+ I G +
Sbjct: 198 -----STPFSDTLAIESMKIIKEYLPKLLDDPENEFYRERIMFASTLAGMVIAQTGTTIA 252
Query: 252 HGLAY 256
H L Y
Sbjct: 253 HALGY 257
>UniRef50_A5G7F4 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Geobacter uraniumreducens Rf4|Rep: Iron-containing
alcohol dehydrogenase - Geobacter uraniumreducens Rf4
Length = 401
Score = 61.3 bits (142), Expect = 3e-08
Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 4/153 (2%)
Query: 23 GINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEF 82
G+ +V+DKV P D G FD +++GGGS D CKA L +S +
Sbjct: 75 GVASEVFDKVTPNPKDHEVMAGAKVLAAGKFDGIISLGGGSSHDCCKAIKLVHSHDGQD- 133
Query: 83 LDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPIL 142
V + G KA P +AI I ++ + K + P
Sbjct: 134 ---VRSFEGAFKATKANTIPQLAINTTSGTGSEVSCFSIINHTDKKYKMALFDPNCTPSK 190
Query: 143 ALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
++ DPL + ++ Y+G D H +E+ T+
Sbjct: 191 SVNDPLIHQCMSGDLAGYTGMDALAHGVEAITS 223
>UniRef50_Q2RJQ1 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Moorella thermoacetica ATCC 39073|Rep:
Iron-containing alcohol dehydrogenase - Moorella
thermoacetica (strain ATCC 39073)
Length = 366
Score = 60.9 bits (141), Expect = 3e-08
Identities = 59/259 (22%), Positives = 102/259 (39%), Gaps = 27/259 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRN-GINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAI 59
+T + A+ S A +++L + I +++V PT + A+ D + I
Sbjct: 35 VTGRHSATASGAMADIEALAKKLDITLATFNQVPSNPTLEVVGRGVEMARSEGADFIIGI 94
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGS +DT KA L ++ V A + P+IAIP
Sbjct: 95 GGGSPLDTAKAIALLATNK-------VPATALYEAELPEPPLPVIAIPTTAGTGSEVTQH 147
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+F E K G S + P+ AL+DP +T ++P +V+ + D HA+E + +
Sbjct: 148 AVFTLPEKKIKKGFSDDRCFPLAALVDPRYTASLPLEVTIDTALDALSHAIEGYLS---- 203
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
+ + P+SD A + ++ V R + A+T+
Sbjct: 204 ---------------RRATPLSDTLALEAMGLFARHKEALVRGELTPATRYDLMYASTLG 248
Query: 240 GVGIGNAGVHLCHGLAYPI 258
G+ I + H L YP+
Sbjct: 249 GMVIAQTRTTILHTLGYPL 267
>UniRef50_A0WAX9 Cluster: Iron-containing alcohol dehydrogenase;
n=3; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Geobacter lovleyi SZ
Length = 383
Score = 60.9 bits (141), Expect = 3e-08
Identities = 52/169 (30%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AAN 72
V SL I++K V P +DA+ K+ N VA+GGGSV D+ K AA
Sbjct: 52 VTASLEGKDISFKALGGVVSNPVISLVRDAVKVVKKHNLQGIVAVGGGSVADSAKAIAAG 111
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
Y D + D+ GKA+ P+ I + EE K
Sbjct: 112 AKY---DGDVWDFF-----IGKAIVKDAIPVFTIMTLAATGSEMNPYGVVTNEETQQKYN 163
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALE-SFTAIPFTE 180
+ AL P ++ I+P TV YS DIF H L+ FTA F E
Sbjct: 164 LGGPALYPKVSAINPELMATVTPDYLAYSAVDIFAHCLDLYFTAKVFPE 212
>UniRef50_Q9XDN0 Cluster: Propanediol utilization propanol
dehydrogenase; n=17; Gammaproteobacteria|Rep:
Propanediol utilization propanol dehydrogenase -
Salmonella typhimurium
Length = 370
Score = 60.5 bits (140), Expect = 4e-08
Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 19/178 (10%)
Query: 83 LDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPIL 142
+D A V + I ++ +AIP + + K + +NAL P +
Sbjct: 94 MDAAKAIVWFSQQSGINIETCVAIPTTSGTGSEVTSACVISDPDKGIKYPLFNNALYPDM 153
Query: 143 ALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISD 202
A++DP ++VP +++ +G D+ HALE++ + ++ A A A + +Q
Sbjct: 154 AILDPELVVSVPPQITANTGMDVLTHALEAWVSPRASDFTDALAEKAAKLVFQ------- 206
Query: 203 VWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
Y +V V R MH A+T+AG+ AG+ L H +A+ + G
Sbjct: 207 ------------YLPTAVEKGDCVATRGKMHNASTLAGMAFSQAGLGLNHAIAHQLGG 252
>UniRef50_Q28JU8 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Jannaschia sp. CCS1|Rep: Iron-containing alcohol
dehydrogenase - Jannaschia sp. (strain CCS1)
Length = 387
Score = 60.5 bits (140), Expect = 4e-08
Identities = 59/228 (25%), Positives = 86/228 (37%), Gaps = 25/228 (10%)
Query: 35 EPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGK 94
EP DA+ A+ D +GGGSV+D KA P DYV G+
Sbjct: 69 EPHLTDVTDAVEIARAARCDVIAGVGGGSVIDLAKAIAALVPAPHPA-QDYVTG----GR 123
Query: 95 AVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVP 154
++ P IAIP + E K + A+ +AL+DP T P
Sbjct: 124 PLDAPPLPFIAIPTTAGTGAEVTRNAVICVPERRQKISLRDTAMIADVALVDPALTDDTP 183
Query: 155 EKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQK 214
V+ SG D +E P +N A N +D R + L
Sbjct: 184 LNVTFGSGLDALVQVIE-----------PYLSNRA--------NAYTDALCRHAI-PLGV 223
Query: 215 YFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAGNV 262
+ + + + +AR + L + G+ + NAG+ HGLA I G V
Sbjct: 224 HALAKLAQGENAQARDDLALVSLFGGLALTNAGLGAVHGLAGVIGGRV 271
>UniRef50_A6LNP6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Thermosipho melanesiensis BI429|Rep:
Iron-containing alcohol dehydrogenase - Thermosipho
melanesiensis BI429
Length = 254
Score = 60.5 bits (140), Expect = 4e-08
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 13 KAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAAN 72
+A+ GI+Y +Y KV PT +A KE + + IGGGS +D K+
Sbjct: 61 EAIEPVFVEKGIDYIIYTKVTPNPTVEQIDEATKIGKEFGATAVIGIGGGSPIDVAKSVA 120
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
+ E+ D + + K + + P+IAI + + H K
Sbjct: 121 IL-----IEYKDKNATELYEQKFIPEKAVPIIAINTTHGTGTEVDRFAVASILDKHYKPA 175
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
I+++ + P+ A+ DP T+P + ++ D H E+ T +
Sbjct: 176 IAYDCIYPMFAIDDPQLMKTLPYNQTKFTSIDAINHVTEAATTL 219
>UniRef50_P33744 Cluster: Aldehyde-alcohol dehydrogenase [Includes:
Alcohol dehydrogenase (EC 1.1.1.1) (ADH); Acetaldehyde
dehydrogenase [acetylating] (EC 1.2.1.10) (ACDH)];
n=131; cellular organisms|Rep: Aldehyde-alcohol
dehydrogenase [Includes: Alcohol dehydrogenase (EC
1.1.1.1) (ADH); Acetaldehyde dehydrogenase [acetylating]
(EC 1.2.1.10) (ACDH)] - Clostridium acetobutylicum
Length = 862
Score = 60.5 bits (140), Expect = 4e-08
Identities = 60/265 (22%), Positives = 113/265 (42%), Gaps = 25/265 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD + +L+ + +++ L I++KV++KV E + K A D+ +A+G
Sbjct: 483 VTDSDPYNLNYVDSIIKILEHLDIDFKVFNKVGREADLKTIKKATEEMSSFMPDTIIALG 542
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAV----NIQVKPM-IAIPXXXXXXXX 115
G M + K + Y P+ +F D + K + + K M +AI
Sbjct: 543 GTPEMSSAKLMWVLYEHPEVKFEDLAIKFMDIRKRIYTFPKLGKKAMLVAITTSAGSGSE 602
Query: 116 XXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
+ K ++ + P +A++D + +P+ ++ YSG D +++E++T+
Sbjct: 603 VTPFALVTDNNTGNKYMLADYEMTPNMAIVDAELMMKMPKGLTAYSGIDALVNSIEAYTS 662
Query: 176 IPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVE-ARSSMHL 234
+ +E A A+R + KY + N E AR M
Sbjct: 663 VYASEYTNGLALEAIRLIF-------------------KYLPEAYKNGRTNEKAREKMAH 703
Query: 235 AATMAGVGIGNAGVHLCHGLAYPIA 259
A+TMAG+ NA + LCH +A ++
Sbjct: 704 ASTMAGMASANAFLGLCHSMAIKLS 728
>UniRef50_Q82WP4 Cluster: Iron-containing alcohol dehydrogenase;
n=7; Proteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Nitrosomonas europaea
Length = 394
Score = 59.7 bits (138), Expect = 8e-08
Identities = 61/250 (24%), Positives = 103/250 (41%), Gaps = 28/250 (11%)
Query: 13 KAVLDSLTRNGINYKVYDKVRVEPTDGSFKD-AIHFAKEGNFDSFVAIGGGSVMDTCKA- 70
+ ++D I ++ + V EP+ D I +A E +F + + IGGGSV+DT KA
Sbjct: 49 RLLIDQFEHRAITWR-HAMVAEEPSPALIDDFVIDYANE-HFAAVIGIGGGSVLDTAKAV 106
Query: 71 ANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYE-EIHA 129
A L +DY+ VG + P IA+P + + E
Sbjct: 107 AGLL--QVQHSVMDYLEG-VGPELSYQGPAVPFIAVPTTAGTGSEATKNAVLSVQGENGF 163
Query: 130 KTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPA 189
K H+ L A++DP + P V +G D LES+ ++
Sbjct: 164 KKSFRHDKLVAEYAIVDPDLLASCPPGVIAANGMDALTQLLESYVSLK------------ 211
Query: 190 LRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDV-EARSSMHLAATMAGVGIGNAGV 248
+N ++D A LQ ++ + + G++ + R M AA ++G+ + G+
Sbjct: 212 -------ANALTDALAISGLQAVRDALLPFYHQQGELAQHREKMAYAALLSGITLAQTGL 264
Query: 249 HLCHGLAYPI 258
HGLA P+
Sbjct: 265 GSVHGLASPL 274
>UniRef50_A4J7X7 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Desulfotomaculum reducens MI-1|Rep: Iron-containing
alcohol dehydrogenase - Desulfotomaculum reducens MI-1
Length = 371
Score = 59.7 bits (138), Expect = 8e-08
Identities = 56/246 (22%), Positives = 100/246 (40%), Gaps = 36/246 (14%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY--- 74
+L + GI Y+++++V P+ + AKE D V IGGGS +D KA +
Sbjct: 53 ALHKEGIEYQIFNEVEQNPSLATVLRGGQRAKEMGADFIVGIGGGSPLDAAKAIAVMAIN 112
Query: 75 -YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
S D + N P+ P +A+P + + K I
Sbjct: 113 EISQQDLMAKKWTNEPL-----------PTVAVPTTAGTGSEVTPYAVLTVDWAETKMSI 161
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPA 193
+ L P LA +D + L +P ++ + D H++E + +
Sbjct: 162 AGEKLFPTLAFLDGRYMLNLPWSITANTAVDALSHSIEGYIS------------------ 203
Query: 194 YQGSNPISDVWARFCLQTLQKYFVRSVN-NSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
+ SD+ A ++ L + +R++N +S + R + A+T+AG+ I G + H
Sbjct: 204 -NRATVYSDLLALESIRILGQ-LLRTINPDSISLAEREELLYASTLAGIVIAQTGTSVVH 261
Query: 253 GLAYPI 258
L YP+
Sbjct: 262 ALGYPL 267
>UniRef50_Q59477 Cluster: 1,3-propanediol dehydrogenase; n=152;
cellular organisms|Rep: 1,3-propanediol dehydrogenase -
Klebsiella pneumoniae
Length = 387
Score = 59.7 bits (138), Expect = 8e-08
Identities = 49/245 (20%), Positives = 99/245 (40%), Gaps = 25/245 (10%)
Query: 16 LDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYY 75
L L GI ++D V P D + +D + + D V +GGGS D K +
Sbjct: 56 LHYLREAGIEVAIFDGVEPNPKDTNVRDGLAVFRREQCDIIVTVGGGSPHDCGKGIGI-A 114
Query: 76 SDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISH 135
+ + + Y + + + P++A+ + E K I
Sbjct: 115 ATHEGDLYQYAGI-----ETLTNPLPPIVAVNTTAGTASEVTRHCVLTNTETKVKFVIVS 169
Query: 136 NALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQ 195
P +++ DPL + P ++ +G D HA+E++ + +
Sbjct: 170 WRNLPSVSINDPLLMIGKPAALTAATGMDALTHAVEAYIS-------------------K 210
Query: 196 GSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLA 255
+NP++D A ++ + + ++V +++AR +M A+ +AG+ NA + H +A
Sbjct: 211 DANPVTDAAAMQAIRLIARNLRQAVALGSNLQARENMAYASLLAGMAFNNANLGYVHAMA 270
Query: 256 YPIAG 260
+ + G
Sbjct: 271 HQLGG 275
>UniRef50_A6CD83 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Planctomyces maris DSM 8797|Rep: Iron-containing
alcohol dehydrogenase - Planctomyces maris DSM 8797
Length = 389
Score = 59.3 bits (137), Expect = 1e-07
Identities = 50/206 (24%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 51 GNFDSFVAIGGGSVMDTCKAANLYYSDPDAE-FLDYVNAPVGKGKAVNIQVKPMIAIPXX 109
G D + IGGGS +D KA + ++ ++E +DY+ VG+G + P++AIP
Sbjct: 89 GAGDFLIGIGGGSGIDLAKATSAMITNQESETVVDYLEG-VGRGLKLTEAPLPLMAIPTT 147
Query: 110 XXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHA 169
+ K + + P + L DP +VP +++ +G D
Sbjct: 148 AGTGSEATKNAVISSYAPPFKKSLRAEQMIPDIVLCDPQLACSVPPEITARTGMDAITQL 207
Query: 170 LESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEAR 229
LES+ + P P L QG + + L + +V N R
Sbjct: 208 LESYIS---CRAQPIPQALCL----QG--------LKLAIPALPE----AVENGNSRRGR 248
Query: 230 SSMHLAATMAGVGIGNAGVHLCHGLA 255
+M AA ++G+ + N+G+ + HG+A
Sbjct: 249 EAMAHAALLSGIALANSGLGMAHGVA 274
>UniRef50_Q3LFI0 Cluster: NADPH-dependent butanol dehydrogenase;
n=1; Propionibacterium freudenreichii subsp.
shermanii|Rep: NADPH-dependent butanol dehydrogenase -
Propionibacterium freudenreichii subsp. shermanii
Length = 376
Score = 58.8 bits (136), Expect = 1e-07
Identities = 63/261 (24%), Positives = 105/261 (40%), Gaps = 38/261 (14%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +AS + M V L I V+D+V+ P + + + ++ +A+G
Sbjct: 31 ITDAFMASSALMDTVRGHLGSAEIT--VFDQVQPNPDVQAVARGLRAFLDCAPEALLALG 88
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +DT KA + P+ G V +P
Sbjct: 89 GGSPIDTAKAVRKIALEQ--------GQPLSAGFYV---------VPTTSGTGSEVSSFA 131
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ E AK ++ + +A++DP T P ++ SG D HA+E++ A+
Sbjct: 132 VVTDPEHDAKLPMTSPDMVADVAILDPDAVRTCPPTLTADSGMDALSHAVEAYVALDH-- 189
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
N I+D A L+ + V S + D+ AR AATMAG
Sbjct: 190 -----------------NDITDALAEKALRLISANLVASFRDGNDLAAREHQQNAATMAG 232
Query: 241 VGIGNAGVHLCHGLAYPIAGN 261
+ N+G+ + HGL++ I G+
Sbjct: 233 IAFENSGLGIVHGLSHAIGGS 253
>UniRef50_Q1JYE4 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Desulfuromonas acetoxidans DSM 684|Rep:
Iron-containing alcohol dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 387
Score = 58.8 bits (136), Expect = 1e-07
Identities = 60/238 (25%), Positives = 96/238 (40%), Gaps = 28/238 (11%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKA-ANL 73
V SL G+++ + V+ P ++ + AK D VA+GGGSV+D KA A
Sbjct: 51 VTASLQAAGLSWVDHGGVKSNPVLSHVREGVAVAKREQVDVVVAVGGGSVLDESKAIAAG 110
Query: 74 YYSDPDA-EFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
D D EF ++ A V K P++ + + E K
Sbjct: 111 ALCDHDVWEF--FLQAKVEK-------ALPLVTVLTLAATGSEMNSGGVVTNENTAQKFN 161
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
I L P +++DP T TVP + YS D H +E + FT A
Sbjct: 162 IGSPLLFPKTSILDPALTYTVPADYTAYSAVDAISHIIEGY----FTSNDQA-------- 209
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHL 250
P+ D + ++T+ + + + +AR++M +AT A G+ AG+ L
Sbjct: 210 -----TPLQDRFVEGLVKTIMESTEQILQQPDHADARATMMWSATWALNGLSTAGIGL 262
>UniRef50_A6P0M2 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 393
Score = 58.8 bits (136), Expect = 1e-07
Identities = 56/249 (22%), Positives = 108/249 (43%), Gaps = 26/249 (10%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V SL G++++ V+ P G ++ + ++ D +A+GGGSV+DT KA
Sbjct: 52 VTASLEEAGLSWQAVGGVQPNPHLGLAQETVDKFRDKGIDFVLAVGGGSVIDTAKAVAHG 111
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
+ PD DY + GK K V + +K ++ + E K GI+
Sbjct: 112 LARPDVPIWDYYS---GKAK-VTVTLKKG-SVLTIAAAGSETSDSAVLTNETNGQKKGIN 166
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
+P A+++P T T+P + + DI H ++ + ++
Sbjct: 167 TPFNQPDFAIMNPALTCTLPPRQTACGVADIMMHTMDRYFSV------------------ 208
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG---VGIGNAGVHLC 251
Q N ++D A L+T+ +Y ++++ D++ARS + +++ G+G
Sbjct: 209 QTDNALTDGIAETLLRTVIEYGRVAMDDPEDLKARSEIMWCGSLSHDGLTGLGQPKDFST 268
Query: 252 HGLAYPIAG 260
H L + ++G
Sbjct: 269 HALGHELSG 277
>UniRef50_A6PUH9 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
Iron-containing alcohol dehydrogenase - Victivallis
vadensis ATCC BAA-548
Length = 396
Score = 58.4 bits (135), Expect = 2e-07
Identities = 60/243 (24%), Positives = 103/243 (42%), Gaps = 23/243 (9%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
++AVL + RN + + ++ EP + + +E N + +A+GGGSVMD KAA
Sbjct: 54 LEAVLRAADRNAVRFS---EIEAEPGVETVERMAALLQEVNPAAVIALGGGSVMDAAKAA 110
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
L + ++ + +I IP + K
Sbjct: 111 YLTMQS-GWKLEEHFGSDCYSRVYPEAAPDRVICIPTTSGTGSEATPYANIVDHRLGVKK 169
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALR 191
IS + P LAL P T ++P V+ +G D H +E F + A AN AL
Sbjct: 170 LISERFIVPALALPIPAFTHSMPPAVTRATGCDALAHLIEGFLNVG------ADANSAL- 222
Query: 192 PAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGI--GNAGV- 248
++ WA ++ + + ++ + G+ AR++M +AAT+ G+ I + G+
Sbjct: 223 ---------ANEWALTGIRLVVENLPAAIADGGNAAARNNMSMAATLGGMVIRFKSTGLP 273
Query: 249 HLC 251
HLC
Sbjct: 274 HLC 276
>UniRef50_A6BJ73 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 371
Score = 58.4 bits (135), Expect = 2e-07
Identities = 51/226 (22%), Positives = 94/226 (41%), Gaps = 25/226 (11%)
Query: 35 EPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGK 94
EPTD + ++ + D +AIGGG+V+D K L + AE + P+ + K
Sbjct: 61 EPTDVMIDALLADFRKTDCDRIIAIGGGAVIDMAKILVLA-GNYTAEEIFGRKVPLKREK 119
Query: 95 AVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVP 154
+IA+P I ++ ++H K G++ + + A++ P +P
Sbjct: 120 T-------LIAVPTTCGAGSEVSNVSIAEFTKLHTKMGLAVDEIYADRAVLIPELLTGLP 172
Query: 155 EKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQK 214
+ S D F HA+ES+ + T + A+ +G I++ + + L
Sbjct: 173 YSFFSTSAIDAFIHAIESYVSPKATLYTQMFSMKAMEMIIEGFRKIAEHGEEYRMNLLDD 232
Query: 215 YFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
+ A+ +AG+ GNAG H ++YP++G
Sbjct: 233 FLT-----------------ASNLAGIAFGNAGTGAVHAMSYPLSG 261
>UniRef50_A5G7G0 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Geobacter uraniumreducens Rf4|Rep: Iron-containing
alcohol dehydrogenase - Geobacter uraniumreducens Rf4
Length = 387
Score = 58.0 bits (134), Expect = 2e-07
Identities = 63/265 (23%), Positives = 107/265 (40%), Gaps = 36/265 (13%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFK-DAIHFAKEGNFDSFVAI 59
++D + S + + ++ G+ YD + P D + A+ + + G D V +
Sbjct: 43 VSDQGLFSAGWVDKAIKNIMDAGLEVIFYDNITPNPKDVEVEAGALEYIRHGA-DVIVGL 101
Query: 60 GGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GGGS MD K + S+ D+ G K + P++ P
Sbjct: 102 GGGSAMDAAKGIAILVSN-GGRIKDFE----GSDKIFR-PLPPLVLCPTTCGTGSDVSQF 155
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
I E H K I + P ++L DP T+P++ + D HALE+F ++
Sbjct: 156 AIITDTEQHCKLTIMSRCVAPDISLTDPDTLETLPDEYVCTTATDALSHALEAFFSV--- 212
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSV--NNSGDVE--ARSSMHLA 235
S ++DV A L+ + V +V + D+E AR+S+H
Sbjct: 213 ----------------ASTSLTDVHAIKALRLVSTSLVEAVRERKAADLENLARASLH-- 254
Query: 236 ATMAGVGIGNAGVHLCHGLAYPIAG 260
AG+ N+ + + H LA+PI G
Sbjct: 255 ---AGMAFSNSLLGIVHALAHPIGG 276
>UniRef50_Q8EVE3 Cluster: NADH-dependent butanol dehydrogenase; n=2;
Mycoplasma penetrans|Rep: NADH-dependent butanol
dehydrogenase - Mycoplasma penetrans
Length = 392
Score = 57.2 bits (132), Expect = 4e-07
Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 5/151 (3%)
Query: 24 INYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFL 83
+ Y + + P + AI FA+E D AIGGGSV+D+ K ++P
Sbjct: 63 LRYVEFGGIEPNPKTDTVYKAILFARENKVDVIFAIGGGSVIDSSKVIGALTANPHLN-- 120
Query: 84 DYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILA 143
D + K VN + +IAI + + + K G+ + P+ A
Sbjct: 121 DVWEYCLDTSKLVNPSI-DIIAITTLAGTASENNSGSVISNSKTNEKYGVFTPSAVPVCA 179
Query: 144 LIDPLHTLTVPEKVSNYSG-FDIFCHALESF 173
+ DP +T TV K SG FD F H E +
Sbjct: 180 IEDPTYTFTV-NKWQTASGIFDCFSHLTEQY 209
>UniRef50_Q87QB5 Cluster: Iron-containing alcohol dehydrogenase;
n=32; Vibrionales|Rep: Iron-containing alcohol
dehydrogenase - Vibrio parahaemolyticus
Length = 439
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/250 (22%), Positives = 98/250 (39%), Gaps = 27/250 (10%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
+++ L + Y+ + + EP ++ ++ D +AIGGGSV+D KA
Sbjct: 72 IINYLKAQNMRYQ-HVAINGEPNITMVEETAVLGRKFQPDMVIAIGGGSVIDMGKALAAI 130
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPM--IAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
+ DYV G+ V ++ KP+ IAIP + + K
Sbjct: 131 IPN-QGNVYDYVEVV---GRNVPLKAKPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVS 186
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
+ + +A++DP T + S D F H +E++ P
Sbjct: 187 LRSPDMLADVAIVDPTLTYGTDQYTSGRGAMDAFTHLMEAYVC----------GEP---- 232
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
NP++D+ L+ L + + +ARS + AA + G+ I NA + H
Sbjct: 233 -----NPLTDMVCEEGLRRLSRSVIAGCKQDNH-KARSDLSFAALLGGMAITNAKLGAAH 286
Query: 253 GLAYPIAGNV 262
GLA + G +
Sbjct: 287 GLASALGGKL 296
>UniRef50_Q11AP6 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Mesorhizobium sp. BNC1|Rep: Iron-containing alcohol
dehydrogenase - Mesorhizobium sp. (strain BNC1)
Length = 378
Score = 56.8 bits (131), Expect = 6e-07
Identities = 60/264 (22%), Positives = 102/264 (38%), Gaps = 24/264 (9%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
++D + + V+ +L G+ Y V+ + PT+ + A+ + D + +G
Sbjct: 35 VSDAGIKHAGHVDKVIANLP-GGLAYSVFLETPPNPTEPAVHAALAQYRTEGCDGLIGLG 93
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXX 120
GGS +D K + + P A Y A +G + + P+IAIP
Sbjct: 94 GGSSIDLAKGVAVLSAHP-APLQQYA-AVMGGQARITDRTAPVIAIPTSAGTGSEVGRGA 151
Query: 121 IFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTE 180
+ + + K GI + P A+ DP T+T + + G D H +E F +
Sbjct: 152 VITFAD-GRKLGILSPHVVPKRAICDPDLTVTASPQQTAAFGMDALVHCIECFVS----- 205
Query: 181 RGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAG 240
P NP+++ A R+V + D EAR M + A M
Sbjct: 206 --PV------------ENPVAEAIAIDGFARAIANLPRAVRDGADREARRQMMVVALMGA 251
Query: 241 VGIGNAGVHLCHGLAYPIAGNVKS 264
+ G H LA+P+ G K+
Sbjct: 252 MSF-QKGCGAVHALAHPLGGLSKT 274
>UniRef50_A1K911 Cluster: Conserved hypothetical alcohol
dehydrogenase; n=1; Azoarcus sp. BH72|Rep: Conserved
hypothetical alcohol dehydrogenase - Azoarcus sp.
(strain BH72)
Length = 369
Score = 56.8 bits (131), Expect = 6e-07
Identities = 53/206 (25%), Positives = 84/206 (40%), Gaps = 23/206 (11%)
Query: 54 DSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXX 113
D +A+GGGSV+D K L P+ + L + P++AIP
Sbjct: 86 DLVIALGGGSVLDAGKVLALLLRRPEPDLL--AQCFRNRRDVAWTARLPLVAIPTTAGAG 143
Query: 114 XXXX-XXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALES 172
++D+E AK ++ P LA++D TLT+P + + Y D HALES
Sbjct: 144 AEVTPFATVWDHER-SAKHSLATPFAYPDLAVLDAALTLTLPPEHTLYPALDALSHALES 202
Query: 173 FTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSM 232
T P AL+ S + +V A+ GD+ R+ M
Sbjct: 203 LWNRSAT---PVSRGLALQALALASRALPEVLAQ----------------PGDLARRADM 243
Query: 233 HLAATMAGVGIGNAGVHLCHGLAYPI 258
A+ +AG+ I + H ++YP+
Sbjct: 244 QHASLLAGMAISQTRTAVAHAISYPL 269
>UniRef50_Q0I6R5 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Synechococcus sp. CC9311|Rep: Iron-containing
alcohol dehydrogenase - Synechococcus sp. (strain
CC9311)
Length = 394
Score = 56.0 bits (129), Expect = 1e-06
Identities = 56/209 (26%), Positives = 86/209 (41%), Gaps = 23/209 (11%)
Query: 54 DSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXX 113
D+ + IGGGSV+D KA ++ LD++ VG+G A + P +AIP
Sbjct: 91 DAVIGIGGGSVIDFGKAIAAMIPHGNS-VLDHLEG-VGRGLAHSGITLPFLAIPTTSGTG 148
Query: 114 XXXXXXXIFDYEEIHA-KTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALES 172
+ + K + H+ P ++D V+ G D F LE
Sbjct: 149 GEVSKNAVLSHVGTDGYKKSLRHDNFVPSAVILDGALLTGAAVDVTAACGMDAFTQLLE- 207
Query: 173 FTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNN-SGDVEARSS 231
PF +P + A+ VW+ LQ L R+ S D + R +
Sbjct: 208 ----PFFSPTASPLSDAI------------VWSG--LQHLVPNLRRACGEGSADPQVRLN 249
Query: 232 MHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
M + +G+G+ NAG+ + HGLA PI G
Sbjct: 250 MAYGSLCSGIGLANAGLGIVHGLAGPIGG 278
>UniRef50_A3UPZ4 Cluster: Alcohol dehydrogenase; n=2; Vibrio|Rep:
Alcohol dehydrogenase - Vibrio splendidus 12B01
Length = 401
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 10/154 (6%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
VY + + T + AI FA N D+ +++GGGSV+D K + +D +
Sbjct: 76 VYTDIAPDATCDNINAAIEFANSVNADAILSVGGGSVIDASKGVKYAFHKQ----IDDIR 131
Query: 88 APVGKGKAVNIQVK------PMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPI 141
+ G +++ P IA+P +F E + K + + L
Sbjct: 132 TVIAGGGHIDVWPNNEDIRVPHIAVPTTAGTGAEASPIAVFYNEHENIKASLVASGLEAD 191
Query: 142 LALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
+A++DP T +P ++ + D HA+E+ +
Sbjct: 192 IAILDPTVTTKLPAHLTRSTAMDALTHAVEAIVS 225
>UniRef50_Q392F4 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Burkholderia sp. 383|Rep: Iron-containing alcohol
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 380
Score = 55.6 bits (128), Expect = 1e-06
Identities = 60/215 (27%), Positives = 90/215 (41%), Gaps = 27/215 (12%)
Query: 48 AKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEF-LDYVNAPVGKGKAVNIQVKPMIAI 106
A G D +A+GGGSV+D+ K + D + + +A +G AV + + P++AI
Sbjct: 80 ALPGKPDVLIALGGGSVIDSAKVLAAEHGDFERVLRILSGDACADRGDAVRLAL-PIVAI 138
Query: 107 PXXXXXXXXXXX-XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDI 165
P ++D K +S L P ++DP + +P + + SG D
Sbjct: 139 PTTAGTGSEVTHWATVWDPHNAR-KLSLSRPDLYPETVIVDPRLMVGLPMQPTLASGLDA 197
Query: 166 FCHALESFTAIPFTERGPAPANPALRP-AYQGSNPISDVWARFCLQTLQKYFVRSVN-NS 223
HALES I ANP R A Q + + R VN +
Sbjct: 198 LSHALESIWNI--------HANPVTRGLAVQAARELIGGLGR-------------VNAHP 236
Query: 224 GDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
D++ARS M L A AG+ N L H ++Y I
Sbjct: 237 DDLDARSDMALGALRAGLAFSNTHTALAHNISYAI 271
>UniRef50_Q97IR6 Cluster: NAD-dependent 4-hydroxybutyrate
dehydrogenase; n=2; Bacteria|Rep: NAD-dependent
4-hydroxybutyrate dehydrogenase - Clostridium
acetobutylicum
Length = 371
Score = 55.2 bits (127), Expect = 2e-06
Identities = 50/226 (22%), Positives = 90/226 (39%), Gaps = 25/226 (11%)
Query: 35 EPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGK 94
EP+D + ++ + + + IGGG+++D CK L P + +D K
Sbjct: 61 EPSDDMIDAIVSDMEKEDINRIIGIGGGTILDICKLLAL---KPTKKSIDLFEK-----K 112
Query: 95 AVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVP 154
++ K +I IP I + + H K G++ + L A+ P T+P
Sbjct: 113 VPIVKEKELILIPTTCGTGSEVTNVSIAEIKSKHTKMGLACDELYADYAVFIPEFVKTLP 172
Query: 155 EKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQK 214
K S D HA+ES+ + + A++ G + ++ ++
Sbjct: 173 FKFFVTSSIDALIHAVESYVSPKANHFTKMFSVEAIKLIINGYKEV--------IKNGEE 224
Query: 215 YFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
Y +N+ + + AG+ GNAGV H L+YP+ G
Sbjct: 225 YKNNIIND---------FIIGSNYAGIAFGNAGVGAVHALSYPLGG 261
>UniRef50_Q0RL39 Cluster: Putative alcohol dehydrogenase with
dehydroquinate synthase-like domain, in ethanolamine
utilization; n=1; Frankia alni ACN14a|Rep: Putative
alcohol dehydrogenase with dehydroquinate synthase-like
domain, in ethanolamine utilization - Frankia alni
(strain ACN14a)
Length = 410
Score = 54.4 bits (125), Expect = 3e-06
Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 33/261 (12%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+ D V+ + V+ L G V+D+V EPTD A A+ + +G
Sbjct: 46 VADRVVSEAGLLATVVGGLADAGFGVTVFDEVAGEPTDTVVARAAELARAHAVSAVAGVG 105
Query: 61 GGSVMDTCKAANLYYSDPD--AEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXX 118
GGS +D KA L ++ A+++ V PV V P++ +P
Sbjct: 106 GGSALDLAKAVALLATNTGGIADWVGVVEPPV--------PVAPLLLVPTTTGTGSEATR 157
Query: 119 XXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPF 178
+ AK+ +S P++A++D +P V +G D H +ES +
Sbjct: 158 ISMITIG--GAKSILSCAQFVPLVAVLDADLVADLPAAVVASTGMDAIAHGVESMLSTTR 215
Query: 179 TERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATM 238
T A A A+ +L++ + GD AR + A+ +
Sbjct: 216 TALTLAVATEAV---------------AILTASLERAAL-----DGDRAARGRVLYASHL 255
Query: 239 AGVGIGNAGVHLCHGLAYPIA 259
+G+ + NAGV L H LAY IA
Sbjct: 256 SGLAL-NAGVVLGHSLAYVIA 275
>UniRef50_A0IVC7 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Serratia proteamaculans 568|Rep: Iron-containing
alcohol dehydrogenase - Serratia proteamaculans 568
Length = 375
Score = 54.0 bits (124), Expect = 4e-06
Identities = 38/124 (30%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 51 GNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXX 110
G VAIGGGSV+D KA P L Y+ +G K ++ P+IAIP
Sbjct: 82 GKAQRVVAIGGGSVLDAAKAFAALVEHP-LPTLRYMEK-IGDTK-ISGATLPLIAIPTTA 138
Query: 111 XXXXXXXXXXIF-DYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHA 169
+ D + K + HN P A++DP P+KV Y D F H
Sbjct: 139 GTGSEVTQNAVITDTQLSKVKASLRHNNFVPHTAILDPQLLEGAPDKVLAYCAIDAFTHL 198
Query: 170 LESF 173
E++
Sbjct: 199 FEAY 202
>UniRef50_UPI000039369F Cluster: COG1979: Uncharacterized
oxidoreductases, Fe-dependent alcohol dehydrogenase
family; n=1; Bifidobacterium longum DJO10A|Rep: COG1979:
Uncharacterized oxidoreductases, Fe-dependent alcohol
dehydrogenase family - Bifidobacterium longum DJO10A
Length = 390
Score = 53.6 bits (123), Expect = 5e-06
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 6/137 (4%)
Query: 43 DAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFL--DYVNAPVGKGKAVNIQV 100
+ + KE +A+GGGSV+D K +L D E L DY+ GK +
Sbjct: 70 EGVRLVKEHGVGLILAVGGGSVIDCAKFISLGSGIGDDEDLWDDYIET----GKPAPEGL 125
Query: 101 KPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNY 160
P+ + + E + K G + L P +++DP + +T+P + + Y
Sbjct: 126 IPVGVVLTTAATGSEMGDAAVLTNWERNRKLGYTSFPLMPRFSVLDPSYLMTLPAEQTVY 185
Query: 161 SGFDIFCHALESFTAIP 177
D+FCH E + + P
Sbjct: 186 GFEDMFCHTCEQYFSYP 202
>UniRef50_Q122F9 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Comamonadaceae|Rep: Iron-containing alcohol
dehydrogenase - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 377
Score = 53.6 bits (123), Expect = 5e-06
Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 28/258 (10%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIG 60
+TD +A+L + L G+ V+ V PT D K D + G
Sbjct: 37 VTDKALAALPVLAEFRTHLA--GLEVAVFSGVFGNPTCSQVMDGAAAYKAHRADCVIGFG 94
Query: 61 GGSVMDTCKAANLYYSDPDAEFLDYV-NAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXX 119
GG+ +D K + + + + L+YV + P + +A+ ++ +A+P
Sbjct: 95 GGAALDVAKVVGVAATH-EGDILEYVWDHP--QVRAITGELPYFVALPTTSGTGSEVGRS 151
Query: 120 XIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ + H K + + + DP TL +P V+ +G D H +ES+
Sbjct: 152 SVVSENDTHLKRVVFSPKILAKVVFADPELTLGLPPHVTAATGMDALTHNIESY------ 205
Query: 180 ERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMA 239
L PAY +P+ D A + + + +V G+++AR M +A+ M
Sbjct: 206 ----------LSPAY---HPLCDGIALEGTRIAARALLTAVKEPGNLQARGDMMMASMMG 252
Query: 240 GVGIGN--AGVHLC-HGL 254
+ VH C H L
Sbjct: 253 AIAFQKDLGAVHSCAHAL 270
>UniRef50_Q1NUM2 Cluster: Iron-containing alcohol dehydrogenase;
n=2; delta proteobacterium MLMS-1|Rep: Iron-containing
alcohol dehydrogenase - delta proteobacterium MLMS-1
Length = 385
Score = 52.8 bits (121), Expect = 9e-06
Identities = 36/151 (23%), Positives = 59/151 (39%), Gaps = 6/151 (3%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
SL G+ ++ ++ P G + I + + VA+GGGSV+D+ KA
Sbjct: 54 SLAAAGVQWRELTGIKPNPELGQVRQGIELVRTHGLTAVVAVGGGSVLDSAKAVAA---- 109
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
A + K++ + P++ +P + EE K GI +
Sbjct: 110 -GAGVAHDIKLFFRGKKSIKTSL-PLLCLPTLAGSGSELNSGMVLTDEERGVKLGIGNRH 167
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCH 168
L P ++DP T TVP + D CH
Sbjct: 168 LFPATTILDPQLTTTVPWPQTLAGAVDAICH 198
>UniRef50_A6PN65 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
Iron-containing alcohol dehydrogenase - Victivallis
vadensis ATCC BAA-548
Length = 367
Score = 52.4 bits (120), Expect = 1e-05
Identities = 57/238 (23%), Positives = 94/238 (39%), Gaps = 30/238 (12%)
Query: 23 GINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPDA 80
G ++++ + EP + A+ A+ S V GGGS MDT K AA L P A
Sbjct: 52 GRSFELIADISPEPPLADVERALAAARRIGAASVVGWGGGSAMDTAKSVAALLPLPGPVA 111
Query: 81 EFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRP 140
++ + N G V + +P + E K + L
Sbjct: 112 DY--FYNRREIPGHGVFLA-----EVPTTAGTGAEITPNAVLLDPETGIKQSLRGTGLYA 164
Query: 141 ILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPI 200
LAL+DP T P V+ SGFD A+ESF + + P A++ A + +
Sbjct: 165 DLALVDPELTYDCPPAVTAASGFDALTQAIESFIS---RKANPVSKTLAMQAAKNILSSL 221
Query: 201 SDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
W SG+++AR+ + + MA + ++G+ HG+ +P+
Sbjct: 222 HPAW------------------SGEIQARNFVAEGSMMAAMAFSSSGLGAVHGIGHPL 261
>UniRef50_Q8D7E3 Cluster: Uncharacterized oxidoreductase; n=6;
Proteobacteria|Rep: Uncharacterized oxidoreductase -
Vibrio vulnificus
Length = 382
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 10/158 (6%)
Query: 22 NGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPD 79
+G +++ + V PT + A+ KE N D +A+GGGSV+D K AA+ +Y
Sbjct: 54 DGYHWQEFSGVEPNPTKETLDKAVAIVKEDNIDFILAVGGGSVIDGSKYVAASAHYHGDG 113
Query: 80 AEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALR 139
+ L GK P+ A+ + E K ++
Sbjct: 114 WDIL--------TGKHHVTSATPLGAVLTLPATGSESNSGAVITKAETQDKLAFLSPYVQ 165
Query: 140 PILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
PI A++DP T+PEK D + H E + P
Sbjct: 166 PIFAVMDPDVMKTLPEKQLLNGIVDAWVHVCEQYITRP 203
>UniRef50_A6VNF5 Cluster: Iron-containing alcohol dehydrogenase;
n=9; Bacteria|Rep: Iron-containing alcohol dehydrogenase
- Actinobacillus succinogenes 130Z
Length = 395
Score = 51.6 bits (118), Expect = 2e-05
Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 5/156 (3%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
SL GI Y V P I K+ D +A+GGGSV+D+ KA ++
Sbjct: 55 SLDNAGIAYTELGGVVPNPLLSLVYQGIDLCKKEGVDFILAVGGGSVIDSAKAIAYGVAE 114
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
PD + + + K P+ + + +E K G S +
Sbjct: 115 PDKDVWELYDR-----KRQAAACLPVATVLTIAAAGSEMSPSSVITKDEGGIKRGYSSDL 169
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
RP ++++P T+T+P+ + DI H +E +
Sbjct: 170 SRPKFSILNPELTMTLPQYQTASGNADILMHTMERY 205
>UniRef50_Q93N32 Cluster: NADH-dependent butanol dehydrogenase BdhA;
n=6; Proteobacteria|Rep: NADH-dependent butanol
dehydrogenase BdhA - Aeromonas hydrophila
Length = 382
Score = 51.2 bits (117), Expect = 3e-05
Identities = 66/245 (26%), Positives = 100/245 (40%), Gaps = 31/245 (12%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AAN 72
V SL +GI+ + P ++AI A++ D+ +++GGGSV+D+ K AA
Sbjct: 52 VSQSLAAHGISLVECGGIVSNPLLSKVREAIAQARDHQVDAVLSVGGGSVLDSSKAIAAG 111
Query: 73 LYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG 132
Y D + +GKG+ + P+ AI + E K
Sbjct: 112 TRYEG------DVWDLFIGKGEIAS--ALPIFAILTLAATGSEMNAGAVVTNEVTKEKFA 163
Query: 133 ISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
I+ P L++++P TV YS DI HA+E + FT A P L+
Sbjct: 164 INSVHTFPRLSIVNPALMQTVSRDYLVYSAADIIAHAIEGY----FT----ASMQPRLQ- 214
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCH 252
S + V A L+T + + D +AR+ AAT+A GI AG
Sbjct: 215 ----SRLVESVIAT-VLETTEALLADPL----DYDARAEFAWAATLALNGITYAGT---S 262
Query: 253 GLAYP 257
G YP
Sbjct: 263 GFGYP 267
>UniRef50_A7B601 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 393
Score = 51.2 bits (117), Expect = 3e-05
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 6/162 (3%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
++++ +L + GI++ V P + I AK+ + D +AIGGGSV+D+ KA
Sbjct: 51 LESISRNLEKEGISWVELGGVLPNPRLSLVYEGIEIAKKEDVDFVIAIGGGSVIDSAKAI 110
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
L + + D+ G AV P+ I + + E K
Sbjct: 111 GL-GAVIKGDVWDFFT-----GAAVPESSLPVGVILTCPATGSESSAVTVVNNTEEGKKL 164
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
+SH +RP++A ++P T ++ +++ D+F H E +
Sbjct: 165 LVSHPLVRPVIAFMNPELTCSLSRFLTSCGVIDMFSHVCERY 206
>UniRef50_A6FNK8 Cluster: Ornithine cyclodeaminase; n=3;
Rhodobacteraceae|Rep: Ornithine cyclodeaminase -
Roseobacter sp. AzwK-3b
Length = 387
Score = 51.2 bits (117), Expect = 3e-05
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 26/206 (12%)
Query: 57 VAIGGGSVMDTCKA--ANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXX 114
VA GGGSV+D KA A + + P E L+ V G+G ++ P +AIP
Sbjct: 96 VACGGGSVIDAGKAIAALVPATRPMLEHLEVV----GQGLPLDHAPLPFVAIPTTAGTGA 151
Query: 115 XXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFT 174
+ E K + + +A++DP T P V+ SG D +E
Sbjct: 152 EVTKNAVIAVPEARRKVSLRDPRMIADVAIVDPALTDGTPWAVTLASGLDAVTQVIE--- 208
Query: 175 AIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHL 234
P + P +N ++D R + + R + EAR +M L
Sbjct: 209 -------------PYVSPK---ANALTDALCRDAIPRGLQALCR-LQEGESSEARDAMAL 251
Query: 235 AATMAGVGIGNAGVHLCHGLAYPIAG 260
+ G+ + NA + HGLA PI G
Sbjct: 252 VSLYGGLALANAALGAVHGLAGPIGG 277
>UniRef50_A1WTC2 Cluster: Iron-containing alcohol dehydrogenase;
n=1; Halorhodospira halophila SL1|Rep: Iron-containing
alcohol dehydrogenase - Halorhodospira halophila (strain
DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM
244 / SL1))
Length = 399
Score = 51.2 bits (117), Expect = 3e-05
Identities = 61/260 (23%), Positives = 98/260 (37%), Gaps = 32/260 (12%)
Query: 6 VASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVM 65
+A L+ + +DSL G V EP+ + G D +A+GGGSV+
Sbjct: 48 LAYLAAAQEAVDSLKAQGWRVATVI-VTGEPSAEWVDEQRQGIPAGGSDLVIALGGGSVL 106
Query: 66 DTCK--AANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFD 123
D K AA P +L+ V G+ + P +A+P +
Sbjct: 107 DVGKTLAAMACEEGPTRAYLEGVGDRTPSGRRL-----PWLAVPTTMGTGSEVTHNAVLG 161
Query: 124 YEEIHA--KTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTER 181
+ K + H ++D T +VP V +G D F LES+ A
Sbjct: 162 QPGLEQGYKKSLRHPHYVADRVVLDARLTASVPRSVVASAGMDAFSQLLESYLA------ 215
Query: 182 GPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMH---LAATM 238
P S+P+ D W + L+ + GD + + H LAA++
Sbjct: 216 -PT------------SSPLLDGWLVYGLELAGGALPELIRRHGDADLEAQRHDMALAASL 262
Query: 239 AGVGIGNAGVHLCHGLAYPI 258
+GV + G+ + HGL P+
Sbjct: 263 SGVALTYTGLGIVHGLIGPL 282
>UniRef50_Q8AAD0 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Bacteroides|Rep: Iron-containing alcohol
dehydrogenase - Bacteroides thetaiotaomicron
Length = 381
Score = 50.4 bits (115), Expect = 5e-05
Identities = 56/219 (25%), Positives = 84/219 (38%), Gaps = 30/219 (13%)
Query: 32 VRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPDAEFLDYVNAP 89
+ P + + AI KE D +A+GGGSV+D K +A L Y D DA L P
Sbjct: 65 IEPNPAIETLRKAIALGKEQKVDYLLAVGGGSVIDGTKLISAGLLY-DGDAWDLVLAGRP 123
Query: 90 VGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLH 149
V K + + ++ +P + E K N P+ +++DP
Sbjct: 124 VTK----TVPLSTVLTLP---ATGSEMNNGAVISRHETKEKYPFYSNF--PLFSILDPEV 174
Query: 150 TLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCL 209
T T+P D F H +E + + G + + D WA L
Sbjct: 175 TFTLPPHQVACGLADTFVHVMEQYMTV------------------AGQSRVMDRWAEGIL 216
Query: 210 QTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGV 248
QTL + + N D + + L+ATMA G GV
Sbjct: 217 QTLVEIAPKIRENQHDYQLMADFMLSATMALNGFIAMGV 255
>UniRef50_A6NPH8 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 359
Score = 50.0 bits (114), Expect = 6e-05
Identities = 56/233 (24%), Positives = 87/233 (37%), Gaps = 41/233 (17%)
Query: 28 VYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVN 87
V+D+V+ +P+ +H + D +A GGGS MD KA + N
Sbjct: 57 VFDQVKPDPSLRLVAQGVHALRAFGPDIVLAFGGGSPMDCAKAMRHFAGG---------N 107
Query: 88 APVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDP 147
P + IP + + K + +AL P A++D
Sbjct: 108 PP-----------PELWCIPTTAGTGSEVTSFAVLTDADAGVKYPLVDDALLPDCAVLDA 156
Query: 148 LHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVWARF 207
VP V+ +G D+ HA E A R P + A+ G S W
Sbjct: 157 SLLAGVPPAVTADTGMDVLTHAAEGCVA-----RKATPFSDAM-----GEKAFSIAWRSL 206
Query: 208 CLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPIAG 260
S ++GD A+ M LA+ +AG+ AG+ +CH LA+ + G
Sbjct: 207 -----------SHAHAGDNAAKGEMLLASCLAGISFNAAGLGICHALAHALGG 248
>UniRef50_Q8KDA2 Cluster: Alcohol dehydrogenase, iron-containing;
n=9; Chlorobiaceae|Rep: Alcohol dehydrogenase,
iron-containing - Chlorobium tepidum
Length = 377
Score = 49.6 bits (113), Expect = 8e-05
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 7/166 (4%)
Query: 15 VLDSLTRNGINYKVY-DKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANL 73
VL ++ N VY ++ R EPT ++ F + D VAIGGGS +D K L
Sbjct: 48 VLRNINACYANAVVYCNEFRGEPTYRHLENVAEFFRRELPDGLVAIGGGSTIDLGKGVAL 107
Query: 74 YYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
++ + L P K V+ V P++ +P +F E+ K GI
Sbjct: 108 LLTN-NVPALSLKGFP----KDVSDPV-PLVTVPSLLGSGAEVSYNAVFIDEDEGRKLGI 161
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFT 179
+ P ++IDP +++ P + S D H ++SF ++ T
Sbjct: 162 NSRKNFPKRSVIDPKLSMSAPMESVIASAMDSLVHCVDSFGSVKHT 207
>UniRef50_Q7M9F4 Cluster: BUTANOL DEHYDROGENASE; n=1; Wolinella
succinogenes|Rep: BUTANOL DEHYDROGENASE - Wolinella
succinogenes
Length = 374
Score = 49.6 bits (113), Expect = 8e-05
Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 10/179 (5%)
Query: 12 MKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA 71
+ + L L + + +++ V P G + I AKE + +AIGGGSV+D KA
Sbjct: 49 LDSTLRRLDEANLLWVLHEGVVSNPELGHVEAGIAKAKEHRVSAILAIGGGSVIDEAKAI 108
Query: 72 NLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKT 131
L + + E Y +A+++ V I + E K
Sbjct: 109 ALGACNEE-EIWSYFLERRPIERALDLFV-----ILTLAATGSEMNGNSVITNERTRHKL 162
Query: 132 GISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPAL 190
I+ L P L++++P ++VP+ YS D H LES+ T + P P +L
Sbjct: 163 SIASPRLNPKLSILNPRLMMSVPDAYIAYSAVDALAHILESY----LTSQKPLPLQDSL 217
>UniRef50_A1VAL7 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Desulfovibrio vulgaris subsp. vulgaris|Rep:
Iron-containing alcohol dehydrogenase - Desulfovibrio
vulgaris subsp. vulgaris (strain DP4)
Length = 392
Score = 49.6 bits (113), Expect = 8e-05
Identities = 62/253 (24%), Positives = 96/253 (37%), Gaps = 25/253 (9%)
Query: 18 SLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD 77
SL G+ + + VR P A+ ++ FVA+GGGSVMDT KAA + +
Sbjct: 55 SLEAAGVAWTPCEGVRPNPDLDGVLRAVQALRDAGAGGFVAVGGGSVMDTAKAAGV-CAL 113
Query: 78 PDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNA 137
D + D+ AV P+ +P + K +
Sbjct: 114 HDGDPWDHFTRRTTATAAV-----PVFTVPTLSGTGAEMNGTAVITNMAQQRKWSL--RG 166
Query: 138 LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGS 197
P+ A +DP++ VP ++ D H LE F G P A G
Sbjct: 167 PTPVAAFLDPVYQRDVPLALAVGCAVDAMTHVLE------FAVAG-TPCVDAKALDIPGG 219
Query: 198 NPISDVWARFCLQTLQKYFVRSV----NNSGDVEARSSMHLAA-----TMAGVGIGNAGV 248
+ + L + +RSV GD AR+S+ AA + GVG+G G
Sbjct: 220 TYFMEETVLAQNEALLRSIIRSVEVLRRIPGDYAARASLAWAAGLGLCGLTGVGLG-GGS 278
Query: 249 HLCHGLAYPIAGN 261
+ H L + ++G+
Sbjct: 279 WVSHALEHAVSGH 291
>UniRef50_Q9XBE8 Cluster: Putative alcohol dehydrogenase; n=1;
Amycolatopsis orientalis|Rep: Putative alcohol
dehydrogenase - Amycolatopsis orientalis
Length = 377
Score = 49.2 bits (112), Expect = 1e-04
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 28/205 (13%)
Query: 54 DSFVAIGGGSVMDTCKAANLYYSDPD-AEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXX 112
D + +GGGS +DT KA L D AE + + P+ + + V P A P
Sbjct: 85 DVVIGVGGGSTLDTAKAVRLLPPTKDEAERVLRGDEPIRVARPPRLVVIPTTAGPGSEVT 144
Query: 113 XXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALES 172
Y + H ++ +ALIDP T + P ++ + D HA+ES
Sbjct: 145 AFATIYVGTRKYS-------LDHPTVKADVALIDPALTHSCPPTLTAHCALDATAHAIES 197
Query: 173 FTAIPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSM 232
+ ++ R AP+ R A PI LQK F R ++ + R +
Sbjct: 198 WWSL----RSSAPSRDLARSALARLVPI-----------LQKGF-RDTSS----QQRELL 237
Query: 233 HLAATMAGVGIGNAGVHLCHGLAYP 257
AA MAG I H AYP
Sbjct: 238 SNAAVMAGQAIDLTRTTAAHAFAYP 262
>UniRef50_A5ELU4 Cluster: Putative alcohol dehydrogenase; n=1;
Bradyrhizobium sp. BTAi1|Rep: Putative alcohol
dehydrogenase - Bradyrhizobium sp. (strain BTAi1 / ATCC
BAA-1182)
Length = 386
Score = 49.2 bits (112), Expect = 1e-04
Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 9/151 (5%)
Query: 29 YDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAA--NLYYSDPDAEFLD-- 84
+D+V T S +A A + D VAIGGGSV+D K L +S DA LD
Sbjct: 64 FDQVPQHTTRDSVVEAAGHAAQAKADLVVAIGGGSVVDAAKIVLMCLEHSITDASGLDGF 123
Query: 85 -YVNAPVG--KGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPI 141
V+ P G G N +V+ MIAIP + D K H + PI
Sbjct: 124 ELVSTPQGPRPGPFRNPKVR-MIAIPSTLSGGEYNAGTLVTDTRR-KLKQIFVHPLMMPI 181
Query: 142 LALIDPLHTLTVPEKVSNYSGFDIFCHALES 172
++DP T+ P + SG H +E+
Sbjct: 182 SIILDPAITVHTPRTLWLGSGTRAMDHGIEA 212
>UniRef50_Q8XM32 Cluster: NADH-dependent butanol dehydrogenase;
n=12; Bacteria|Rep: NADH-dependent butanol dehydrogenase
- Clostridium perfringens
Length = 390
Score = 48.8 bits (111), Expect = 1e-04
Identities = 39/159 (24%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
+LDSL + G++ V+ P K I K D +A+GGGSV+D+ KA L
Sbjct: 52 ILDSLNKAGLHVIELGGVKPNPRLSLVKKGIELCKNSKVDFILAVGGGSVIDSAKAIALG 111
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
D + D+ + KA + + ++ IP + E+ K
Sbjct: 112 V-PYDGDVWDFFTKNIKIEKA--LPLGTVLTIP---AAGSESSSGTVITNEDGWYKRSTG 165
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
L P ++++P T+PE DI H +E +
Sbjct: 166 SPLLYPKFSMLNPELCFTLPEYQIASGSADILAHLMERY 204
>UniRef50_Q8R6C2 Cluster: NADPH-dependent butanol dehydrogenase;
n=3; Fusobacterium nucleatum|Rep: NADPH-dependent
butanol dehydrogenase - Fusobacterium nucleatum subsp.
nucleatum
Length = 372
Score = 48.8 bits (111), Expect = 1e-04
Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 42/262 (16%)
Query: 1 MTDPNVASLSPMKAVLDSLTRNGINYKVYDKVRVEPT----DGSFKDAIHFAKEGNFDSF 56
+TD + L V +SL+ ++DKV P+ + KD I F E
Sbjct: 31 VTDEVMTQLRLTDFVTNSLSST-TEINIFDKVEPNPSVATIENGLKDFIGFEPE----CV 85
Query: 57 VAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXX 116
+A+GGGS +D CK LY++ + Y + K K IAIP
Sbjct: 86 IALGGGSSIDACKGI-LYFA-----YKLYKKLNINKKKIF------FIAIPTTSGTGSEV 133
Query: 117 XXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAI 176
+ E H K ++++ + P +AL+ +P KV +G D+ HALE++ +
Sbjct: 134 TSYSVVTNGE-H-KIALANDLMLPDVALLSTKFLGALPAKVVADTGMDVLTHALEAYVS- 190
Query: 177 PFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAA 236
+NP S A ++ + + V N+ + ++ A+
Sbjct: 191 ------------------TNANPFSSSLAIKSIKMIFENLVTHYNDRKIEGPKRNVQFAS 232
Query: 237 TMAGVGIGNAGVHLCHGLAYPI 258
MAG+ N+ + + H +A+ +
Sbjct: 233 CMAGIAFDNSSLGINHSIAHTV 254
>UniRef50_Q73LF0 Cluster: Alcohol dehydrogenase, iron-containing;
n=2; Bacteria|Rep: Alcohol dehydrogenase,
iron-containing - Treponema denticola
Length = 391
Score = 48.8 bits (111), Expect = 1e-04
Identities = 56/257 (21%), Positives = 101/257 (39%), Gaps = 25/257 (9%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
++ L + GI YK + P ++ I +E D + +GGGS +D KA +
Sbjct: 51 IIKKLDQAGIFYKELSGISPNPRIEEVEEGIKIVREHKLDFILPVGGGSTIDCSKAVSAG 110
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
+ + + D + GKA V P+ + + + K G
Sbjct: 111 VNYAGSAW-DLIT-----GKAEIKNVLPIGTVLTLSATGSEMNCGAVISNLKTKEKLGFG 164
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAY 194
L P +++DP +T +VP+ + DI H E + ++ N AY
Sbjct: 165 APPLLPKFSVLDPEYTYSVPKNQTAAGTADIMSHTFECYFSL----------NDG---AY 211
Query: 195 QGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGL 254
+ D +A L+T +Y ++ N EARS++ A T A G+ + G +
Sbjct: 212 -----LQDRFAESILKTCIEYGPLAIKNPESYEARSNLMWAGTWAINGLLSDGKKTAWSV 266
Query: 255 AYPIAGNVKSFVPEDYG 271
+P+ + +F +G
Sbjct: 267 -HPMEHELSAFYDITHG 282
>UniRef50_Q2G5I2 Cluster: Iron-containing alcohol dehydrogenase;
n=2; Alphaproteobacteria|Rep: Iron-containing alcohol
dehydrogenase - Novosphingobium aromaticivorans (strain
DSM 12444)
Length = 392
Score = 48.8 bits (111), Expect = 1e-04
Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 8/156 (5%)
Query: 48 AKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPDAEFLDYVNAPV-GKGKAVN-IQVKP- 102
A+ D V++GGGSV D+ K A L + E + ++ V G G +N + V P
Sbjct: 88 ARAAGADLIVSVGGGSVTDSAKIVALLLKHDVRSVEAFEPLHVYVDGDGNVINPLAVGPD 147
Query: 103 --MIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNY 160
+I +P D E + K G H + P++ ++DP T+ PE +
Sbjct: 148 VRVICVPTTLSGGEFNALSGATD-EAVQHKQGYEHRDMAPVMVVLDPALTVYTPEWLWLS 206
Query: 161 SGFDIFCHALESFTAIPFTERGPAPANPALRPAYQG 196
+G HA+E+ + + A+ ALR +G
Sbjct: 207 TGVRSVDHAVETLASHLSNDFADGLADSALRLLVEG 242
>UniRef50_Q46856 Cluster: Alcohol dehydrogenase yqhD; n=123;
cellular organisms|Rep: Alcohol dehydrogenase yqhD -
Escherichia coli (strain K12)
Length = 387
Score = 48.8 bits (111), Expect = 1e-04
Identities = 37/173 (21%), Positives = 70/173 (40%), Gaps = 5/173 (2%)
Query: 5 NVASLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSV 64
+V + VLD+L G++ + + P + +A+ +E +A+GGGSV
Sbjct: 40 SVKKTGVLDQVLDAL--KGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSV 97
Query: 65 MDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDY 124
+D K + P E +D + GK + + PM + +
Sbjct: 98 LDGTKFIAAAANYP--ENIDPWHILQTGGKEIKSAI-PMGCVLTLPATGSESNAGAVISR 154
Query: 125 EEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
+ K ++P+ A++DP++T T+P + D F H +E + P
Sbjct: 155 KTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKP 207
>UniRef50_Q9KVA0 Cluster: Iron-containing alcohol dehydrogenase
family protein RfbM; n=7; Vibrio cholerae|Rep:
Iron-containing alcohol dehydrogenase family protein
RfbM - Vibrio cholerae
Length = 374
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/232 (25%), Positives = 95/232 (40%), Gaps = 15/232 (6%)
Query: 35 EPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDP--DAEFLDYVNA-PVG 91
EP+ I ++ D +A+GGGS++D K A L+Y P ++E L A P
Sbjct: 71 EPSVEELSGVIGELEDFKPDYILALGGGSIIDGAKLAWLFYECPTLESELLYRPFALPSL 130
Query: 92 KGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTL 151
+G+A AIP + ++K + + P L ++DP
Sbjct: 131 RGRA------KFAAIPTTVGAGSEVSSAAVMLDSVTNSKKAVVTHDFLPDLVILDPDLVS 184
Query: 152 TVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPIS-DVWARFCLQ 210
VP KV + D HA+E + ++ A A+ Y+ + S D W+ L
Sbjct: 185 EVPPKVLKTTVADALSHAIEGYVSLIDNPLMNTFAEQAVSIIYRYRHQFSNDNWSSEMLS 244
Query: 211 TLQKYFVRSVNNSGDVEARSSMHLAATMA-GVGIGNAGVHLCHGLAYPIAGN 261
LQ ++ +G V+ + L+ +A +G N G L +GL P N
Sbjct: 245 ELQ----QAAMFAGWVQNHCIVGLSHAIAHQLGTFNIGHGLANGLLMPAVIN 292
>UniRef50_Q8Y7V3 Cluster: Lmo1166 protein; n=12; Listeria|Rep:
Lmo1166 protein - Listeria monocytogenes
Length = 372
Score = 48.0 bits (109), Expect = 3e-04
Identities = 48/234 (20%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 25 NYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLD 84
N ++ V +P + A + +A GGGS +DT K +YY A+ L+
Sbjct: 54 NVHIFTDVVPDPPISKVAGGVSEAGKIQPQVMIAFGGGSAIDTAK--GIYYF---AKRLE 108
Query: 85 YVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILAL 144
+N + IAIP + K + + L P +A+
Sbjct: 109 KIN------------ISTFIAIPTTSGTGSEVTAATVITDPTTKIKYPLFLDELIPDMAI 156
Query: 145 IDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPAYQGSNPISDVW 204
+D +TVP ++ +G D+ HA+E++ + + ++ +D
Sbjct: 157 LDAQLVVTVPPAITANTGMDVLTHAIEAYVS-------------------KDASDYTDAL 197
Query: 205 ARFCLQTLQKYFVRSVNNSGDVEARSSMHLAATMAGVGIGNAGVHLCHGLAYPI 258
+Q ++ ++ ++ R MH A+TMAG+ A + L H +A+ +
Sbjct: 198 GEKSVQLTLRFLTSCYDDGRNLADREKMHNASTMAGMAFNCANLGLNHSIAHQL 251
>UniRef50_Q64T53 Cluster: Putative alcohol dehydrogenase; n=1;
Bacteroides fragilis|Rep: Putative alcohol dehydrogenase
- Bacteroides fragilis
Length = 378
Score = 48.0 bits (109), Expect = 3e-04
Identities = 32/145 (22%), Positives = 57/145 (39%), Gaps = 10/145 (6%)
Query: 36 PTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKA 95
P + I + +AIGGGSV+D K ++S Y G
Sbjct: 66 PKMEDLEKGIELLNDSGSSLVLAIGGGSVLDMAKLIRFFFS--------YSGDKTGNSFR 117
Query: 96 VNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPE 155
+ P+I +P + + I K ++H + P +A++D T P+
Sbjct: 118 KEQDLLPLIVLPTTAGTGSEATHFAVLYKDNI--KYSVAHRDILPDVAIVDSRFTYRNPQ 175
Query: 156 KVSNYSGFDIFCHALESFTAIPFTE 180
++ +GFD A+E++ + TE
Sbjct: 176 YLTACTGFDALAQAIEAYWNVNATE 200
>UniRef50_Q9KLP1 Cluster: Iron-containing alcohol dehydrogenase;
n=25; Vibrionales|Rep: Iron-containing alcohol
dehydrogenase - Vibrio cholerae
Length = 382
Score = 47.6 bits (108), Expect = 3e-04
Identities = 37/151 (24%), Positives = 59/151 (39%), Gaps = 10/151 (6%)
Query: 29 YDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPDAEFLDYV 86
+ V PT + A+H K + D +A+GGGSV+D K AA +Y + L
Sbjct: 61 FSGVEPNPTKETLDKAVHIVKNQHIDFILAVGGGSVIDGSKYVAAAAFYEGDGWDIL--- 117
Query: 87 NAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALID 146
G+ Q P+ AI + E K A++P A++D
Sbjct: 118 -----TGQHTVKQATPIGAILTLPATGSESNTGAVITKAETQDKLAFLSPAVQPRFAVLD 172
Query: 147 PLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
P ++PE+ D + H E + +P
Sbjct: 173 PDVMKSLPERQLVNGLVDAWVHVCEQYLTLP 203
>UniRef50_Q4P7J9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 418
Score = 47.6 bits (108), Expect = 3e-04
Identities = 42/156 (26%), Positives = 64/156 (41%), Gaps = 15/156 (9%)
Query: 42 KDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQVK 101
++A+ K N D +A+GGGS +D KA + Y + +Y G
Sbjct: 89 REAVQRIKRSNADVIIAVGGGSPIDAAKAVSFYRHEQ-----EYGQESARSGTTSADLFI 143
Query: 102 PMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYS 161
P IA+P F ++ H K G+S L P + D TL PE++ +
Sbjct: 144 PTIAVPTTLSVAETTQNAG-FKSDQGH-KIGVSSKNLVPRAVIYDAELTLDTPERLWLST 201
Query: 162 GFDIFCHALESFTAIPFTERGPAPANPALRPAYQGS 197
G HA+E + P T +P LRP+ Q +
Sbjct: 202 GIRALDHAIE-YLYRPDT-------HPLLRPSVQSA 229
>UniRef50_Q89VQ0 Cluster: Maleylacetate reductase; n=5;
Bradyrhizobiaceae|Rep: Maleylacetate reductase -
Bradyrhizobium japonicum
Length = 407
Score = 46.8 bits (106), Expect = 6e-04
Identities = 31/131 (23%), Positives = 53/131 (40%), Gaps = 3/131 (2%)
Query: 44 AIHFAKEGNFDSFVAIGGGSVMDTCKAANLYYSD--PDAEFLDYVNAPVGKGKAVNIQVK 101
A + A+E D V +GGGS+ D KA L ++ D + ++ + G +N
Sbjct: 104 AANAAREVGADLIVTVGGGSITDGAKAVQLCLANGIDDVDGIERIRVHKGVAPEMNAPTV 163
Query: 102 PMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYS 161
I++P + D H K + H P ++DP T+ PE + +
Sbjct: 164 RQISVPTTIAGGEFSAIAGVTD-RSTHVKQMLRHPLTVPRATILDPAITVHTPEWLFLST 222
Query: 162 GFDIFCHALES 172
G H +E+
Sbjct: 223 GIRAVDHCVEA 233
>UniRef50_Q30WM6 Cluster: Alcohol dehydrogenase, iron-containing;
n=1; Desulfovibrio desulfuricans G20|Rep: Alcohol
dehydrogenase, iron-containing - Desulfovibrio
desulfuricans (strain G20)
Length = 389
Score = 46.8 bits (106), Expect = 6e-04
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V SL G+ + ++ V P+ + I A DS +AIGGGSV+D KA
Sbjct: 52 VTASLDGAGVMHTLFSGVTPNPSLDLVEKGIAAAHAFAVDSVLAIGGGSVIDCAKAI--- 108
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGIS 134
FL+ A V + V Q P+ + + E + K +S
Sbjct: 109 ---AAGVFLEDYWAQVETRRPVT-QALPVFTVLTLSGTGSEMNEKAVITNEPLARKWSLS 164
Query: 135 HNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESF 173
L P +++IDP +VP ++ G D H +E++
Sbjct: 165 GLCLCPRVSIIDPQLQSSVPWHLTAAGGIDAMTHVMENY 203
>UniRef50_A0VE95 Cluster: Iron-containing alcohol dehydrogenase;
n=4; Burkholderiales|Rep: Iron-containing alcohol
dehydrogenase - Delftia acidovorans SPH-1
Length = 680
Score = 46.8 bits (106), Expect = 6e-04
Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 23/203 (11%)
Query: 57 VAIGGGSVMDTCKAANLYYSDPDAEFLDYVNAPVGKGKAVNIQV-KPMIAIPXXXXXXXX 115
VA+GGGS +D+ KA L + P F + + A + +G A+ K +IAIP
Sbjct: 406 VALGGGSAIDSAKA--LMCATPTRRFGELLQA-LEQGLALPAAGHKALIAIPTTAGTGSE 462
Query: 116 XXXXXIFDYEEIHAKTGISHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTA 175
+ K + + P A+ID ++P + SG D HALES
Sbjct: 463 VTPWATIWDQAAGRKHSLHQHWTWPEAAIIDAQLMQSLPAGATLASGLDALSHALES--- 519
Query: 176 IPFTERGPAPANPALRPAYQGSNPISDVWARFCLQTLQKYFVRSVNNSGDVEARSSMHLA 235
I R P A+ G+ AR L TL + + G + RS M A
Sbjct: 520 IWNRHRNPVSTTLAV-----GA-------ARRTLATLPAL----MQDLGSLPLRSRMAEA 563
Query: 236 ATMAGVGIGNAGVHLCHGLAYPI 258
A MAG+ N L H L+Y I
Sbjct: 564 ALMAGLAFSNTRTALAHSLSYDI 586
>UniRef50_Q9Z659 Cluster: NADH-dependent butanol dehydrogenase;
n=14; cellular organisms|Rep: NADH-dependent butanol
dehydrogenase - Zymomonas mobilis
Length = 385
Score = 45.2 bits (102), Expect = 0.002
Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 9/154 (5%)
Query: 26 YKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCK--AANLYYSDPDAEFL 83
Y + + P+ + A+ K+ D +A+GGGSV+D K AA + Y E L
Sbjct: 59 YFEFGGIEPNPSYETLMKAVEQVKQEKVDFLLAVGGGSVIDGTKFVAAAVPYEGEPWEIL 118
Query: 84 DYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGISHNALRPILA 143
+ GK + + P+ + + + I +K G ++ + P+ +
Sbjct: 119 ET------DGKKIK-EALPVGTVLTLPATGSEMNRNSVVTRKSIKSKRGFHNDHVFPVFS 171
Query: 144 LIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIP 177
++DP T+P + D F H E + P
Sbjct: 172 ILDPTKVYTLPPRQLANGVVDSFIHITEQYLTYP 205
>UniRef50_A6A276 Cluster: NADH-dependent butanol dehydrogenase a;
n=6; Bacteria|Rep: NADH-dependent butanol dehydrogenase
a - Vibrio cholerae MZO-2
Length = 389
Score = 45.2 bits (102), Expect = 0.002
Identities = 48/207 (23%), Positives = 85/207 (41%), Gaps = 14/207 (6%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANL- 73
VL L+ G N V PT + + +E +A+GGGSV+D K ++
Sbjct: 52 VLAMLSAAGKNVVELSGVMPNPTYAKMMEGVAKVREHKVSLILAVGGGSVIDCAKGISVS 111
Query: 74 YYSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTGI 133
Y + F Y + + V+ ++ P+ +I + +E + K G
Sbjct: 112 AYCEGQDPFQKY----WVEFQDVDHEIVPVASILTMVGTGSEMNGGSVITHEAMKYKAGR 167
Query: 134 SHNA-LRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRP 192
A + P ++++P +T TVP+ FD H +E + F+++G + +
Sbjct: 168 VFPANVFPKFSILNPEYTFTVPQYQMVSGVFDTMSHLMEQY----FSDQGANTTDYVIES 223
Query: 193 AYQGSNPISDVWARFCLQTLQKYFVRS 219
+ S I ++ R LQ Q Y RS
Sbjct: 224 LLKSS--IDNL--RLALQNPQDYEARS 246
>UniRef50_UPI0000499FE8 Cluster: alcohol dehydrogenase,
iron-containing; n=1; Entamoeba histolytica
HM-1:IMSS|Rep: alcohol dehydrogenase, iron-containing -
Entamoeba histolytica HM-1:IMSS
Length = 475
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 8 SLSPMKAVLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFV-AIGGGSVMD 66
SL + V N ++Y +YDK+ P S K+ + K NF F+ IGGGS +D
Sbjct: 43 SLGIIDIVKQVFKENNVDYFIYDKITPNPLYTSVKECVDLTK--NFGDFILGIGGGSAID 100
Query: 67 TCKAANLYYSDPDAEFLDYVNAPV 90
KA +L + D D PV
Sbjct: 101 AAKAVSLMKNGVDILNSDGNGIPV 124
>UniRef50_A6AXJ9 Cluster: NADH-dependent butanol dehydrogenase a;
n=3; Bacteria|Rep: NADH-dependent butanol dehydrogenase
a - Vibrio parahaemolyticus AQ3810
Length = 389
Score = 44.8 bits (101), Expect = 0.002
Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 12/206 (5%)
Query: 15 VLDSLTRNGINYKVYDKVRVEPTDGSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAANLY 74
V+ SL+ G V PT + + +E N + +A+GGGSV+D K ++
Sbjct: 52 VMASLSAAGKKVVELSGVMPNPTYDKMMEGVQLVREHNVNLILAVGGGSVVDCAKGISV- 110
Query: 75 YSDPDAEFLDYVNAPVGKGKAVNIQVKPMIAIPXXXXXXXXXXXXXIFDYEEIHAKTG-I 133
E D + + + V P+ +I + +EE K G +
Sbjct: 111 --SAHCEGQDPFQKYWVEWQDLANDVVPVASILTMVGTGSEMNGGSVITHEETKFKAGRV 168
Query: 134 SHNALRPILALIDPLHTLTVPEKVSNYSGFDIFCHALESFTAIPFTERGPAPANPALRPA 193
A P ++++P +T TV + FD H +E + FT++G + +
Sbjct: 169 FPPAAYPKFSILNPEYTFTVSQYQMVSGVFDTMSHLMEQY----FTDQGANTTDYVIESL 224
Query: 194 YQGSNPISDVWARFCLQTLQKYFVRS 219
+ S I ++ R L+T Y RS
Sbjct: 225 LKSS--IDNL--RVALKTPDDYEARS 246
>UniRef50_Q5V2L6 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 407
Score = 44.8 bits (101), Expect = 0.002
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 9/151 (5%)
Query: 39 GSFKDAIHFAKEGNFDSFVAIGGGSVMDTCKAAN-LYYSDPDAEFLDYVNAPVGKGKAVN 97
G+ D + +E + D VA+GGGS +D K + L +D D + A G
Sbjct: 85 GTAYDGLERFREADADCLVAVGGGSSLDVAKIISILAATDRDPTAVGTAFADSGTIAVPE 144
Query: 98 IQVKPMIAIPXXXXXXXXXXXXXIFDYEEI-----HAKTGISHNALRPILALIDPLHTLT 152
+ P+IA+P + + A G+S L P A DP T
Sbjct: 145 AALPPIIAVPTTLAGADLSIVAGVTAAPDTCPVDEPASGGVSDPELMPAAACYDPELIAT 204
Query: 153 VPEKV---SNYSGFDIFCHALESFTAIPFTE 180
P V S +GFD L + A P T+
Sbjct: 205 TPRSVLAASAMNGFDKGIETLYAANATPITD 235
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 299,846,721
Number of Sequences: 1657284
Number of extensions: 11980356
Number of successful extensions: 26822
Number of sequences better than 10.0: 280
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 26135
Number of HSP's gapped (non-prelim): 491
length of query: 271
length of database: 575,637,011
effective HSP length: 99
effective length of query: 172
effective length of database: 411,565,895
effective search space: 70789333940
effective search space used: 70789333940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)
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