Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002661-TA|BGIBMGA002661-PA|IPR000152|Aspartic acid and
asparagine hydroxylation site, IPR013032|EGF-like region,
IPR000742|EGF-like, type 3, IPR001881|EGF-like calcium-binding,
IPR002172|Low density lipoprotein-receptor, class A,
IPR000033|Low-density lipoprotein receptor, YWTD repeat,
IPR002016|Haem peroxidase, plant/fungal/bacterial, IPR008197|Whey
acidic protein, core region, IPR006210|EGF, IPR006209|EGF-like,
IPR013091|EGF calcium-binding, IPR011061|Antihaemostatic protein
(766 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 674 0.0
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 674 0.0
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 674 0.0
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 674 0.0
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 674 0.0
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 674 0.0
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 674 0.0
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 674 0.0
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 671 0.0
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 600 e-171
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 600 e-171
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 600 e-171
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 600 e-171
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 600 e-171
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 600 e-171
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 597 e-170
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 584 e-166
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 584 e-166
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 573 e-163
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 573 e-163
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 573 e-163
AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein... 573 e-163
AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein... 573 e-163
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 571 e-162
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 571 e-162
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 547 e-155
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 547 e-155
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 539 e-152
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 539 e-152
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 539 e-152
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 537 e-152
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 526 e-148
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 526 e-148
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 526 e-148
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 526 e-148
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 510 e-144
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 510 e-144
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 499 e-140
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 493 e-139
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 477 e-134
AK054663-1|BAB70786.1| 820|Homo sapiens umor (LRPDIT) mRNA. pr... 461 e-129
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 452 e-126
AC008178-1|AAY24266.1| 773|Homo sapiens unknown protein. 433 e-120
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 430 e-120
AC010740-1|AAY14689.1| 862|Homo sapiens unknown protein. 427 e-119
AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppres... 425 e-118
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 403 e-111
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 385 e-106
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 380 e-105
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 380 e-105
BC126405-1|AAI26406.1| 1613|Homo sapiens low density lipoprotein... 299 2e-80
BC117136-1|AAI17137.1| 1613|Homo sapiens low density lipoprotein... 299 2e-80
AF074264-1|AAC33006.1| 1613|Homo sapiens LDL receptor-related pr... 299 2e-80
X55077-1|CAA38905.1| 591|Homo sapiens alpha-2 macroglobulin rec... 282 4e-75
AF283321-1|AAK52433.1| 1611|Homo sapiens low density lipoprotein... 272 3e-72
AF077820-1|AAC72791.1| 1615|Homo sapiens LDL receptor member LR3... 272 3e-72
AF064548-1|AAC36467.1| 1615|Homo sapiens low-density lipoprotein... 272 3e-72
AB209683-1|BAD92920.1| 1477|Homo sapiens low density lipoprotein... 272 3e-72
AB017498-1|BAA33051.1| 1615|Homo sapiens Lipoprotein Receptor Re... 272 3e-72
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 259 3e-68
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 243 2e-63
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 242 4e-63
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 242 4e-63
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 242 4e-63
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 242 4e-63
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 234 1e-60
Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein. 221 1e-56
U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein. 221 1e-56
AC073319-1|AAX93075.1| 585|Homo sapiens unknown protein. 190 2e-47
S73145-1|AAB30825.1| 268|Homo sapiens calcium sensor protein pr... 178 7e-44
AC117947-1|AAX88968.1| 346|Homo sapiens unknown protein. 176 3e-43
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 161 6e-39
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 161 6e-39
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 161 6e-39
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 161 6e-39
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 156 2e-37
BC045606-1|AAH45606.1| 1114|Homo sapiens NID1 protein protein. 156 2e-37
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 156 2e-37
AL139161-1|CAI23421.1| 1114|Homo sapiens nidogen 1 protein. 156 2e-37
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 156 2e-37
AL122018-1|CAI22680.1| 1114|Homo sapiens nidogen 1 protein. 156 2e-37
BC139736-1|AAI39737.1| 224|Homo sapiens LRP5L protein protein. 155 7e-37
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 153 2e-36
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 153 2e-36
AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein... 151 9e-36
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 150 2e-35
AL450467-1|CAH72452.1| 173|Homo sapiens very low density lipopr... 146 3e-34
BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein. 140 2e-32
BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein. 140 2e-32
BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein. 140 2e-32
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein. 139 3e-32
AC108036-1|AAX93208.1| 449|Homo sapiens unknown protein. 134 1e-30
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 121 1e-26
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 121 1e-26
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 121 1e-26
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 121 1e-26
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 121 1e-26
BC110451-1|AAI10452.1| 1042|Homo sapiens corin, serine peptidase... 116 3e-25
AF133845-1|AAD31850.1| 1042|Homo sapiens corin protein. 116 3e-25
BC042754-1|AAH42754.2| 345|Homo sapiens low density lipoprotein... 101 7e-21
AK075546-1|BAC11689.1| 345|Homo sapiens protein ( Homo sapiens ... 101 7e-21
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 101 7e-21
BC030532-1|AAH30532.1| 855|Homo sapiens suppression of tumorige... 99 7e-20
BC018146-1|AAH18146.1| 422|Homo sapiens ST14 protein protein. 99 7e-20
BC005826-1|AAH05826.2| 526|Homo sapiens ST14 protein protein. 99 7e-20
AF283256-1|AAG13949.1| 325|Homo sapiens serine protease SNC19 p... 99 7e-20
AF133086-1|AAF00109.1| 855|Homo sapiens membrane-type serine pr... 99 7e-20
AF118224-1|AAD42765.2| 855|Homo sapiens matriptase protein. 99 7e-20
AF057145-1|AAG15395.1| 855|Homo sapiens serine protease TADG15 ... 99 7e-20
AB030036-1|BAB20376.1| 855|Homo sapiens prostamin protein. 99 7e-20
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 97 3e-19
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 97 3e-19
CR457174-1|CAG33455.1| 282|Homo sapiens 8D6A protein. 95 8e-19
BC007083-1|AAH07083.1| 282|Homo sapiens CD320 molecule protein. 95 8e-19
BC000668-1|AAH00668.1| 282|Homo sapiens CD320 molecule protein. 95 8e-19
AY358420-1|AAQ88786.1| 282|Homo sapiens SGGW198 protein. 95 8e-19
AL365455-1|CAB97010.1| 282|Homo sapiens 8D6 antigen protein. 95 8e-19
AK222623-1|BAD96343.1| 282|Homo sapiens 8D6 antigen variant pro... 95 8e-19
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 95 8e-19
AF161254-1|AAF61850.1| 282|Homo sapiens 8D6 antigen protein. 95 8e-19
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 94 2e-18
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 93 4e-18
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 93 4e-18
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 93 4e-18
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 93 4e-18
CR456446-1|CAG30332.1| 824|Homo sapiens dJ1170K4.2 protein. 90 2e-17
AY358398-1|AAQ88764.1| 802|Homo sapiens PVAE354 protein. 90 2e-17
AY055384-1|AAL16414.1| 811|Homo sapiens type II transmembrane s... 90 2e-17
AY055383-1|AAL16413.1| 811|Homo sapiens type II transmembrane s... 90 2e-17
AL022314-2|CAI19335.1| 788|Homo sapiens protein ( Human DNA seq... 90 2e-17
AJ319876-1|CAC85953.1| 802|Homo sapiens matriptase-2 protein. 90 2e-17
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 89 4e-17
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 89 4e-17
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 89 4e-17
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 89 4e-17
BC032109-1|AAH32109.1| 859|Homo sapiens low density lipoprotein... 87 2e-16
AF166350-1|AAD44360.1| 859|Homo sapiens ST7 protein protein. 87 2e-16
AB208957-1|BAD92194.1| 793|Homo sapiens suppression of tumorige... 87 2e-16
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 86 4e-16
AL590103-10|CAI12134.1| 179|Homo sapiens heparan sulfate proteo... 86 4e-16
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 85 7e-16
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 85 7e-16
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 85 7e-16
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 83 4e-15
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 83 4e-15
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 83 4e-15
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 83 4e-15
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 83 4e-15
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 83 4e-15
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 83 4e-15
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 81 1e-14
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 81 1e-14
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 81 1e-14
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 81 1e-14
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 81 1e-14
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 81 1e-14
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 81 1e-14
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 80 3e-14
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 80 3e-14
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 80 3e-14
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 80 3e-14
BC113716-1|AAI13717.1| 713|Homo sapiens low density lipoprotein... 77 2e-13
BC113714-1|AAI13715.1| 713|Homo sapiens low density lipoprotein... 77 2e-13
BC064901-1|AAH64901.1| 457|Homo sapiens LRP10 protein protein. 77 2e-13
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 77 2e-13
AY358399-1|AAQ88765.1| 713|Homo sapiens LRP10 protein. 77 2e-13
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 77 2e-13
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 77 2e-13
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 77 2e-13
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 77 2e-13
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 77 2e-13
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 75 7e-13
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 75 7e-13
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 75 7e-13
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 75 7e-13
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 75 9e-13
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 75 9e-13
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 75 9e-13
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 75 9e-13
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 75 1e-12
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 75 1e-12
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 75 1e-12
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 75 1e-12
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 75 1e-12
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 75 1e-12
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 75 1e-12
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 75 1e-12
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 75 1e-12
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 75 1e-12
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 74 2e-12
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 74 2e-12
BC088378-1|AAH88378.1| 377|Homo sapiens LRP10 protein protein. 74 2e-12
BC007408-1|AAH07408.1| 770|Homo sapiens low density lipoprotein... 74 2e-12
AK129963-1|BAC85262.1| 284|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AK126750-1|BAC86671.1| 644|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 74 2e-12
AB009462-1|BAA32330.1| 770|Homo sapiens LDL receptor related pr... 74 2e-12
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 74 2e-12
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 74 2e-12
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 74 2e-12
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 74 2e-12
BC117322-1|AAI17323.1| 572|Homo sapiens TMPRSS7 protein protein. 74 2e-12
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 74 2e-12
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 74 2e-12
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 74 2e-12
AK131211-1|BAD18401.1| 572|Homo sapiens protein ( Homo sapiens ... 74 2e-12
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 73 3e-12
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 73 3e-12
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 73 3e-12
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 73 3e-12
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 73 3e-12
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 73 3e-12
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 73 3e-12
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 73 3e-12
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 73 3e-12
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 73 3e-12
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 73 3e-12
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 73 3e-12
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 73 3e-12
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 73 3e-12
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 73 4e-12
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 71 1e-11
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 71 1e-11
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 71 1e-11
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 71 1e-11
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 71 1e-11
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 71 2e-11
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 71 2e-11
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 71 2e-11
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 71 2e-11
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 71 2e-11
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 71 2e-11
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 71 2e-11
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 71 2e-11
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 70 4e-11
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 69 5e-11
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 69 6e-11
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 69 6e-11
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 69 6e-11
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 69 6e-11
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 69 6e-11
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 68 1e-10
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 68 1e-10
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 68 1e-10
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 68 1e-10
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 68 1e-10
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 68 1e-10
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 68 1e-10
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 67 2e-10
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 67 2e-10
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 67 2e-10
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 67 2e-10
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 67 2e-10
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 67 2e-10
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 66 3e-10
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 66 3e-10
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 66 4e-10
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 66 4e-10
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 66 4e-10
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 66 4e-10
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 65 8e-10
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 65 8e-10
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 65 8e-10
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 65 8e-10
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 65 8e-10
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 65 8e-10
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 65 8e-10
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 65 8e-10
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 65 8e-10
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 64 1e-09
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 63 3e-09
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 63 3e-09
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 63 3e-09
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 63 3e-09
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 63 3e-09
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 63 3e-09
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 63 3e-09
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 63 3e-09
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 63 3e-09
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 63 3e-09
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 63 4e-09
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 63 4e-09
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 63 4e-09
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 63 4e-09
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 62 9e-09
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 62 9e-09
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 62 9e-09
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 61 1e-08
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 61 1e-08
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 61 1e-08
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 61 2e-08
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 61 2e-08
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 60 2e-08
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 60 2e-08
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 60 2e-08
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 60 2e-08
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 60 2e-08
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 60 3e-08
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 60 3e-08
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 60 3e-08
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 60 3e-08
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 60 3e-08
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 60 3e-08
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 60 3e-08
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 60 3e-08
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 60 3e-08
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 60 3e-08
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 60 3e-08
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 60 3e-08
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 60 4e-08
BC127709-1|AAI27710.1| 166|Homo sapiens Unknown (protein for MG... 59 5e-08
BC127708-1|AAI27709.1| 205|Homo sapiens low density lipoprotein... 59 5e-08
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 59 5e-08
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 59 5e-08
AL353898-1|CAI22661.1| 205|Homo sapiens low density lipoprotein... 59 5e-08
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 59 5e-08
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 59 5e-08
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 59 5e-08
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 59 5e-08
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 59 7e-08
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 58 9e-08
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 58 9e-08
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 58 9e-08
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 58 1e-07
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 58 1e-07
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 58 1e-07
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 58 1e-07
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 58 1e-07
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 58 1e-07
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 58 1e-07
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 58 1e-07
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 58 1e-07
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 58 1e-07
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 57 2e-07
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 57 2e-07
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 57 3e-07
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 57 3e-07
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 56 4e-07
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 56 4e-07
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 56 4e-07
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 56 4e-07
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 56 4e-07
Y00318-2|CAA68417.1| 321|Homo sapiens protein ( Human mRNA for ... 56 5e-07
Y00318-1|CAA68416.1| 565|Homo sapiens protein ( Human mRNA for ... 56 5e-07
J02770-1|AAA52455.1| 583|Homo sapiens IF protein. 56 5e-07
BC020718-1|AAH20718.1| 377|Homo sapiens CFI protein protein. 56 5e-07
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 56 5e-07
BC141811-1|AAI41812.1| 540|Homo sapiens matrilin 4 protein. 55 8e-07
AK074597-1|BAC11083.1| 540|Homo sapiens protein ( Homo sapiens ... 55 8e-07
AK074595-1|BAC11081.1| 488|Homo sapiens protein ( Homo sapiens ... 55 8e-07
AC020594-1|AAY15036.1| 150|Homo sapiens unknown protein. 55 8e-07
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 54 1e-06
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 54 1e-06
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 54 1e-06
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 54 1e-06
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 54 1e-06
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 54 1e-06
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 54 1e-06
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 54 1e-06
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 54 2e-06
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 54 2e-06
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 54 2e-06
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 54 2e-06
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 54 2e-06
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 54 2e-06
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 54 2e-06
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 54 2e-06
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 53 4e-06
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 52 6e-06
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 52 8e-06
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 52 8e-06
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 52 8e-06
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 52 8e-06
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 52 8e-06
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 52 8e-06
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 52 8e-06
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 52 8e-06
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 52 8e-06
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 52 8e-06
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 52 1e-05
U59436-1|AAB02658.1| 46|Homo sapiens low-density lipoprotein r... 51 2e-05
X84076-1|CAA58883.1| 550|Homo sapiens DGCR2 gene protein. 50 3e-05
X83545-1|CAA58536.1| 550|Homo sapiens cell surface protein prot... 50 3e-05
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 50 3e-05
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 50 3e-05
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 50 3e-05
D79985-1|BAA11480.1| 550|Homo sapiens KIAA0163 protein. 50 3e-05
CR456433-1|CAG30319.1| 550|Homo sapiens DGCR2 protein. 50 3e-05
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 50 3e-05
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 50 3e-05
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 50 3e-05
BC040500-1|AAH40500.1| 550|Homo sapiens DiGeorge syndrome criti... 50 3e-05
BC032430-1|AAH32430.1| 550|Homo sapiens DiGeorge syndrome criti... 50 3e-05
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 50 3e-05
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 50 3e-05
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 50 3e-05
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 50 3e-05
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 50 3e-05
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 50 3e-05
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 50 3e-05
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 50 3e-05
Y08725-1|CAA69975.1| 717|Homo sapiens BMP1-6 protein. 50 4e-05
U50330-1|AAA93462.1| 986|Homo sapiens procollagen C-proteinase ... 50 4e-05
M22488-1|AAA51833.1| 730|Homo sapiens BMP1 protein. 50 4e-05
AB209590-1|BAD92827.1| 803|Homo sapiens bone morphogenetic prot... 50 4e-05
BT007425-1|AAP36093.1| 513|Homo sapiens serine protease inhibit... 49 5e-05
BC018702-1|AAH18702.1| 513|Homo sapiens serine peptidase inhibi... 49 5e-05
BC004140-1|AAH04140.1| 513|Homo sapiens serine peptidase inhibi... 49 5e-05
AY358969-1|AAQ89328.1| 529|Homo sapiens HAI-1 protein. 49 5e-05
AY296715-1|AAP44001.1| 529|Homo sapiens hepatocyte growth facto... 49 5e-05
AB000095-1|BAA25014.1| 513|Homo sapiens hepatocyte growth facto... 49 5e-05
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 49 7e-05
X72177-1|CAA50994.1| 934|Homo sapiens complement component C6 p... 48 9e-05
U91963-1|AAB93878.1| 1013|Homo sapiens tolloid-like protein prot... 48 9e-05
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 48 9e-05
L35279-1|AAC41710.1| 284|Homo sapiens bone morphogenetic protei... 48 9e-05
J05064-1|AAA51860.1| 934|Homo sapiens C6 protein. 48 9e-05
J05024-1|AAA59668.1| 934|Homo sapiens completement component C6... 48 9e-05
J04506-1|AAB59433.1| 491|Homo sapiens complement component C6 p... 48 9e-05
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 48 9e-05
BC035723-1|AAH35723.1| 934|Homo sapiens C6 protein protein. 48 9e-05
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 48 9e-05
AF282732-1|AAF86287.1| 1013|Homo sapiens tolloid-like protein pr... 48 9e-05
AB126592-1|BAD02321.1| 934|Homo sapiens complement component 6 ... 48 9e-05
Y19124-1|CAB65555.1| 1019|Homo sapiens enteropeptidase protein. 48 1e-04
U09860-1|AAC50138.1| 1019|Homo sapiens enterokinase protein. 48 1e-04
BC111749-1|AAI11750.1| 1019|Homo sapiens protease, serine, 7 (en... 48 1e-04
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 48 1e-04
AL163217-2|CAB90389.1| 904|Homo sapiens human enterokinase; EC ... 48 1e-04
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 48 1e-04
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 48 1e-04
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 48 1e-04
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 48 1e-04
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 48 2e-04
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 48 2e-04
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 48 2e-04
Y08724-1|CAA69974.1| 622|Homo sapiens BMP1-5 protein. 47 2e-04
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 47 3e-04
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 47 3e-04
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 47 3e-04
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 47 3e-04
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 47 3e-04
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 47 3e-04
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 47 3e-04
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 47 3e-04
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 47 3e-04
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 46 4e-04
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 46 4e-04
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 46 4e-04
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 46 4e-04
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 46 4e-04
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 46 4e-04
BC113577-1|AAI13578.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
BC112366-1|AAI12367.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
BC112341-1|AAI12342.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
BC088371-1|AAH88371.1| 273|Homo sapiens EGF-like-domain, multip... 46 5e-04
BC012377-1|AAH12377.1| 273|Homo sapiens EGF-like-domain, multip... 46 5e-04
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 46 5e-04
AY358902-1|AAQ89261.1| 273|Homo sapiens VEMF protein. 46 5e-04
AY358901-1|AAQ89260.1| 273|Homo sapiens VEMF protein. 46 5e-04
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 46 5e-04
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 46 5e-04
AL391136-1|CAH72234.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 46 5e-04
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 46 5e-04
AL138765-2|CAI13580.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
AL136181-1|CAH72983.1| 1015|Homo sapiens tolloid-like 2 protein. 46 5e-04
AF059516-1|AAD42979.1| 1015|Homo sapiens tolloid-like 2 protein ... 46 5e-04
AB125649-1|BAD01469.1| 273|Homo sapiens VE-statin protein. 46 5e-04
AB023149-1|BAA76776.2| 1078|Homo sapiens KIAA0932 protein protein. 46 5e-04
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 46 7e-04
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 46 7e-04
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 46 7e-04
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 46 7e-04
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 46 7e-04
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 46 7e-04
AY358903-1|AAQ89262.1| 273|Homo sapiens VEMF protein. 46 7e-04
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 46 7e-04
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 46 7e-04
AL590226-1|CAH71721.1| 273|Homo sapiens EGF-like-domain, multip... 46 7e-04
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 46 7e-04
AF186111-1|AAF01429.1| 273|Homo sapiens NOTCH4-like protein pro... 46 7e-04
>S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprotein
receptor protein.
Length = 845
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>DQ067198-1|AAY46157.1| 873|Homo sapiens very low density
lipoprotein receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>AL450467-4|CAH72455.1| 845|Homo sapiens very low density
lipoprotein receptor protein.
Length = 845
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>AL450467-3|CAH72454.1| 873|Homo sapiens very low density
lipoprotein receptor protein.
Length = 873
Score = 674 bits (1665), Expect = 0.0
Identities = 314/731 (42%), Positives = 422/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EL 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 282 bits (691), Expect = 4e-75
Identities = 194/632 (30%), Positives = 288/632 (45%), Gaps = 48/632 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C +GY++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGS 629
+ L L + RVYW+D + + N + GS
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGS 676
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 671 bits (1658), Expect = 0.0
Identities = 313/731 (42%), Positives = 421/731 (57%), Gaps = 21/731 (2%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 147
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 148 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 206
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 207 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 265
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 266 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 321
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 322 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 381
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC Y D CKA
Sbjct: 382 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRAYQMDLATGV-CKAVGKE 440
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+
Sbjct: 441 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDD 500
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
R V + + + +AVDWVY +YWTD I ++ L G RK L L EP +
Sbjct: 501 KVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPAS 560
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++PL G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K
Sbjct: 561 IAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSK 620
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ +SS + +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E
Sbjct: 621 LHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--EH 678
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPN 735
T + L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+
Sbjct: 679 ATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPS 738
Query: 736 GLKLLPDDQMC 746
G + + + C
Sbjct: 739 GYNVEENGRDC 749
Score = 280 bits (686), Expect = 2e-74
Identities = 193/640 (30%), Positives = 291/640 (45%), Gaps = 48/640 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 127
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 128 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 185
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 186 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 245
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 246 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 299
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 300 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 357
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 358 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 410
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
++ GY C+C + Y++ + C+ + + ++ I + G + E + R
Sbjct: 411 INLKGGYKCECSRAYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKE-YIQLVEQLR 469
Query: 427 DRTRCKATEGHPSLLFA--RKHDIRKISLD-----HHEMVAIVNDTKSATALDYVFRTGM 479
+ A L +A + I S+D H +M+ V + +A A+D+V++T
Sbjct: 470 NTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYN-PAAIAVDWVYKT-- 526
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSD 538
I+W+D + I A +D GT+R + L +AVD + +YW+D G IE +
Sbjct: 527 IYWTDAASKTISVATLD-GTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAG 585
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
+ G R+ L+ ++ P I L+ ++ ++W D ++ + ++G R ++
Sbjct: 586 MNGFDRRPLVTADIQWPNGITLDLIKSRLYWLD-SKLHMLSSVDLNGQDRRIVLKSLEFL 644
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHS 637
+ L L + RVYW+D + + N + GS ++++
Sbjct: 645 AHPLALTIFEDRVYWIDGENEAVYGANKFTGSEHATLVNN 684
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 275 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 331
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 332 IDISKVCNQEQDCRDWSDEPLKECHINEC 360
>L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 21 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 79
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 80 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 139
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 140 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 198
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 199 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 254
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 255 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 313
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 314 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 373
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 374 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 432
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 433 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 492
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 493 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 552
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 553 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 612
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 613 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 670
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 671 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 716
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 256
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 257 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 308
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 309 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 361
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 362 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 420
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 421 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 480
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 481 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 539
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 540 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 598
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 599 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 632
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 220 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 279
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDE 308
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 241
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 242 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 298
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 299 ARDCRDWSDEPI--KECGTNECLDNNGGC 325
>BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein
receptor (familial hypercholesterolemia) protein.
Length = 860
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 21 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 79
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 80 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 139
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 140 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 198
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 199 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 254
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 255 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 313
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 314 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 373
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 374 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 432
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 433 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 492
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 493 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 552
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 553 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 612
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 613 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 670
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 671 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 716
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 256
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 257 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 308
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 309 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 361
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 362 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 420
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 421 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 480
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 481 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 539
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 540 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 598
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 599 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 632
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 220 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 279
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDE 308
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 241
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 242 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 298
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 299 ARDCRDWSDEPI--KECGTNECLDNNGGC 325
>BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein
receptor (familial hypercholesterolemia) protein.
Length = 860
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 21 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 79
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 80 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 139
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 140 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 198
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 199 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 254
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 255 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 313
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 314 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 373
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 374 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 432
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 433 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 492
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 493 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 552
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 553 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 612
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 613 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 670
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 671 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 716
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 256
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 257 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 308
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 309 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 361
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 362 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 420
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 421 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 480
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 481 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 539
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 540 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 598
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 599 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 632
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 220 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 279
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDE 308
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 241
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 242 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 298
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 299 ARDCRDWSDEPI--KECGTNECLDNNGGC 325
>AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 21 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 79
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 80 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 139
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 140 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 198
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 199 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 254
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 255 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 313
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 314 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 373
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 374 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 432
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 433 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 492
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 493 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 552
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 553 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 612
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 613 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 670
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 671 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 716
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 256
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 257 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 308
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 309 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 361
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 362 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 420
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 421 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 480
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 481 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 539
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 540 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 598
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 599 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 632
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 220 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 279
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDE 308
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 241
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 242 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 298
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 299 ARDCRDWSDEPI--KECGTNECLDNNGGC 325
>AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 21 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 79
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 80 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 139
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 140 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 198
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 199 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 254
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 255 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 313
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 314 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 373
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 374 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 432
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 433 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 492
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 493 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 552
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 553 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 612
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 613 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 670
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 671 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 716
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 143 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 256
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 257 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 308
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 309 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 361
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 362 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 420
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 421 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 480
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 481 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 539
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 540 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 598
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 599 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 632
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 220 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 279
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 280 NKFKCHSGECITLDKVCNMARDCRDWSDE 308
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 241
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 242 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 298
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 299 ARDCRDWSDEPI--KECGTNECLDNNGGC 325
>AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein
receptor precursor variant protein.
Length = 870
Score = 600 bits (1482), Expect = e-171
Identities = 284/706 (40%), Positives = 400/706 (56%), Gaps = 24/706 (3%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKP 117
TA C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+
Sbjct: 33 TAVGDRCERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRV 91
Query: 118 GECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
C+P W CD DC +GSDE+ C +TC DEF C +GKCI ++V
Sbjct: 92 NRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSD 151
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCI 231
E CP TC P S F C CI W CD D DC DGSDE G SPC
Sbjct: 152 EASCPVLTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCS 210
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY 291
+ EF C C+H +W E E C TCR D+FQC D +CI G+
Sbjct: 211 AFEFHCLSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQ 266
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC 351
C+ DC D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP C
Sbjct: 267 CDREYDCKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKEC 325
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
G NEC NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G
Sbjct: 326 GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEG 385
Query: 412 TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATAL 471
+KC+C G+ DP + CKA L F +H++RK++LD E +++ + ++ AL
Sbjct: 386 GYKCQCEEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL 444
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTD 528
D + I+WSD++ I +D + VI + DGLAVDW+++++YWTD
Sbjct: 445 DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTD 504
Query: 529 TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
+ + ++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G
Sbjct: 505 SVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDI 564
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
++V+ +++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+
Sbjct: 565 YSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA 624
Query: 649 TFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV 708
FED V+WTD A++ AN+ G DV + L +P + ++H QP GVN C
Sbjct: 625 VFEDKVFWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERT 682
Query: 709 ---NGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
NG C +LCLPAP+ P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 683 TLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAE 728
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 39 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 96
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 97 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 154
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 155 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 214
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 215 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 268
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 269 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 320
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 321 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 373
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 374 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 432
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 433 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 492
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 493 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 551
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 552 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 610
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 611 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 644
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 119 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 173
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 174 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 231
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 232 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 291
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 292 NKFKCHSGECITLDKVCNMARDCRDWSDE 320
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 199 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 253
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 254 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 310
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 311 ARDCRDWSDEPI--KECGTNECLDNNGGC 337
>AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein
receptor protein.
Length = 837
Score = 597 bits (1473), Expect = e-170
Identities = 281/700 (40%), Positives = 397/700 (56%), Gaps = 24/700 (3%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPL 123
C+ F+C DG CI W CD +A+C DGSDE Q C C +F+C G+ C+P
Sbjct: 4 CERNEFQC-QDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQ 62
Query: 124 TWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT 182
W CD DC +GSDE+ C +TC DEF C +GKCI ++V E CP
Sbjct: 63 FWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPV 122
Query: 183 PTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV-----GCVSTPKVRSPCISTEFEC 237
TC P S F C CI W CD D DC DGSDE G SPC + EF C
Sbjct: 123 LTCGPAS-FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHC 181
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKD 297
C+H +W E E C TCR D+FQC D +CI G+ C+ D
Sbjct: 182 LSG-ECIHSSWRCDGGPDCKDKSDE--ENC-AVATCRPDEFQCSDGNCIHGSRQCDREYD 237
Query: 298 CPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECE 357
C D SDE C T+C+ +F C G CI L KVC+ DC ++ DEP CG NEC
Sbjct: 238 CKDMSDEVGCVNV-TLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECL 296
Query: 358 KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCEC 417
NNGGCS C D IGY C C G++L+ R CEDIDEC DP +CSQ+C+N +G +KC+C
Sbjct: 297 DNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQC 356
Query: 418 HTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRT 477
G+ DP + CKA L F +H++RK++LD E +++ + ++ ALD +
Sbjct: 357 EEGFQLDPHTKA-CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVAS 415
Query: 478 GMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHI 534
I+WSD++ I +D + VI + DGLAVDW+++++YWTD+ +
Sbjct: 416 NRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTV 475
Query: 535 ELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSY 594
++D +G RK L R+ +PRAI ++P+ G+M+WTDWG KI++ G++G ++V+
Sbjct: 476 SVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTE 535
Query: 595 DVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWV 654
+++WPNG+TLDL+ R+YWVD+K+++ISS + +G R+ IL + L HPFS+ FED V
Sbjct: 536 NIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKV 595
Query: 655 YWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAV---NGH 711
+WTD A++ AN+ G DV + L +P + ++H QP GVN C NG
Sbjct: 596 FWTDIINEAIFSANRLTGSDVNLL--AENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGG 653
Query: 712 CSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
C +LCLPA + P+SP+ +CACP+G+ L D + C+ +++
Sbjct: 654 CQYLCLPASQINPHSPKFTCACPDGMLLARDMRSCLTEAE 693
Score = 225 bits (551), Expect = 3e-58
Identities = 177/634 (27%), Positives = 271/634 (42%), Gaps = 59/634 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 4 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 61
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 62 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 119
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C TC F C + CI W E +C P S F
Sbjct: 120 CPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 179
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+CI + W CDG DC D SDE C + C EF+C+D C+H +
Sbjct: 180 HCLSGECIHSSWRCDGGPDCKDKSDEENCAV-----ATCRPDEFQCSDG-NCIHGSRQCD 233
Query: 252 XXXXXXXXXXEA----LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + LC G ++F+C CI CN +DC D SDE
Sbjct: 234 REYDCKDMSDEVGCVNVTLCEGP-----NKFKCHSGECITLDKVCNMARDCRDWSDE--- 285
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVC-DKHVD----CPN-FEDEPRDRCGE-NECEKNN 360
C D GG C S VC D + CP+ F+ + RC + +EC+ +
Sbjct: 286 --PIKECGTNECLDNNGG-C---SHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DP 338
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHT 419
CSQ CV+ GY C CE+G++L + + C+ + A ++ + + + E +T
Sbjct: 339 DTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE-YT 397
Query: 420 GYARDPRDRTRCKATEGHPSLLFA--RKHDIRKISLDHHEMVA-----IVNDTKSATALD 472
+ R+ + ++ + I LD V+ I D ++ L
Sbjct: 398 SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA 457
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG-H 531
+ I+W+D + A +G +R + E + VD V+ +YWTD G
Sbjct: 458 VDWIHSNIYWTDSVLGTVSVAD-TKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP 516
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
I+ L G L+ + ++ P I L+ L G ++W D ++ I ++G +R TI
Sbjct: 517 AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVD-SKLHSISSIDVNGGNRKTI 575
Query: 592 VSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+ + + + +L + +V+W D I S N
Sbjct: 576 LEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSAN 609
Score = 147 bits (356), Expect = 1e-34
Identities = 79/209 (37%), Positives = 101/209 (48%), Gaps = 19/209 (9%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + + C F+C + CI
Sbjct: 84 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLTCGPASFQC-NSSTCI 138
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 139 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 196
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQ 188
PDC D SDE+ C TCR DEF C +G CI EV C T C+
Sbjct: 197 PDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGP 256
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+ F C G+CI+ C+ DC D SDE
Sbjct: 257 NKFKCHSGECITLDKVCNMARDCRDWSDE 285
Score = 119 bits (286), Expect = 4e-26
Identities = 89/270 (32%), Positives = 113/270 (41%), Gaps = 29/270 (10%)
Query: 144 ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTD--GQCI 199
+ C +EF C +GKCI +WV E + C + TC+ FSC +CI
Sbjct: 2 DRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCK-SGDFSCGGRVNRCI 60
Query: 200 SAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXX 259
+W CDG VDC +GSDE GC PK C EF C+D C+ R +V
Sbjct: 61 PQFWRCDGQVDCDNGSDEQGC--PPKT---CSQDEFRCHDG-KCISRQFVCDSDRDCLDG 114
Query: 260 XXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--------YNCTRQK 311
EA C +TC FQC +CIP C+ DC DGSDE Y
Sbjct: 115 SDEA--SC-PVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDS 171
Query: 312 TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDT 370
+ C EF C G CI S CD DC + DE + C C + CS C+
Sbjct: 172 SPC-SAFEFHCLSGECIHSSWRCDGGPDCKDKSDE--ENCAVATCRPDEFQCSDGNCIHG 228
Query: 371 PIGYYCDCEKGYK-LIDNRTCEDIDECADP 399
CD E K + D C ++ C P
Sbjct: 229 --SRQCDREYDCKDMSDEVGCVNVTLCEGP 256
Score = 106 bits (255), Expect = 3e-22
Identities = 62/149 (41%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRF 71
+Y F +S C++ EF C +G CI SW+CD DC D SDE+ AT C+ F
Sbjct: 164 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE-NCAVAT---CRPDEF 218
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEAC-GPEEFTCRGKPGECVPLTWMCDD 129
+C SDG CI S +CD DC D SDE C V C GP +F C GEC+ L +C+
Sbjct: 219 QC-SDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHS--GECITLDKVCNM 275
Query: 130 NPDCSDGSDEKACNETCRSDEFTCGNGKC 158
DC D SDE + C ++E NG C
Sbjct: 276 ARDCRDWSDEPI--KECGTNECLDNNGGC 302
>AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein
receptor-related protein 4 protein.
Length = 1950
Score = 584 bits (1443), Expect = e-166
Identities = 299/730 (40%), Positives = 394/730 (53%), Gaps = 41/730 (5%)
Query: 23 CTSSEFRCKTGR-----CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
C S F C CIP W+CD + DC D SDED + C F C +G
Sbjct: 75 CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPT----CSPLDFHC-DNG 129
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CI RSW CD DC D SDE C C +EF C+ G C+ W CD + DC D S
Sbjct: 130 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQN--GYCIRSLWHCDGDNDCGDNS 187
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH---FSCT 194
DE+ C EF C +G CI W E CP+ P + F C
Sbjct: 188 DEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCA 247
Query: 195 DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXX 254
G+CI +HCDGD DC D SDE C S PC S EF C+ + C++ W
Sbjct: 248 YGRCILDIYHCDGDDDCGDWSDESDCSS----HQPCRSGEFMCDSGL-CINAGWRCDGDA 302
Query: 255 XXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTIC 314
E C ++ C +QF+C C+ + C+G DC D SDE NC +
Sbjct: 303 DCDDQSDE--RNCTTSM-CTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQ 359
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC----GENECEKNNGGCSQRCVD 369
+F C G CI K+C+ DC + DE P+ C GE C NNGGC+Q+C
Sbjct: 360 CALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQM 419
Query: 370 TPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
C C GY+L D TC+D++ECA+ G CSQ C N +G F+C C TGY P DR
Sbjct: 420 VRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRP-DR 478
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDE 488
CKA P LLFA + DIR++ E ++N+ ++A ALD+ R ++FWSDV +
Sbjct: 479 RSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLD 538
Query: 489 KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILI 548
+I +A ++ G+ V+ L + GLAVDWV++ LYWTD+G + IE+++L G RK+L+
Sbjct: 539 RILRANLN-GSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLL 597
Query: 549 RDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
LE+PRAIAL+P+EG ++WTDWG P+IE + MDGS R I + WPNGLT+D
Sbjct: 598 WQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAG 657
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+R+YWVDAK + I N DGS R+ ++ ++ L HPF+IT FED +YWTDW ++ AN
Sbjct: 658 RRMYWVDAKHHVIERANLDGSHRKAVI--SQGLPHPFAITVFEDSLYWTDWHTKSINSAN 715
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPR 728
KF GK+ E I + L PM IH HP RQP G N C NG C+HLCLP+ G N
Sbjct: 716 KFTGKNQEII--RNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPS---GQN--- 767
Query: 729 VSCACPNGLK 738
+CACP G +
Sbjct: 768 YTCACPTGFR 777
Score = 293 bits (720), Expect = 1e-78
Identities = 150/357 (42%), Positives = 210/357 (58%), Gaps = 17/357 (4%)
Query: 394 DECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
+ C D G C+ +C+ + C C TG+ + + A LLFAR+ DIR+IS
Sbjct: 748 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRKIS---SHACAQSLDKFLLFARRMDIRRIS 804
Query: 453 LDHHEM---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQL 509
D ++ V + D +SA ALD+ R ++W+DV+ + I +A D GT + VV+ L
Sbjct: 805 FDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWD-GTGQEVVVDTSL 863
Query: 510 ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFW 569
+ GLA+DWV N LYWTD G + IE+++ G+MR +LI + L+ PR I + P+ G+M+W
Sbjct: 864 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 923
Query: 570 TDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGS 629
TDWG PKIERAGMD S R I+S ++ WPNGL +D QR+YW DA M TI DGS
Sbjct: 924 TDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGS 983
Query: 630 GRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMV 689
R++++ S L HPF +T + + +YWTDW ++ A++ G D E T L+N M
Sbjct: 984 KRKVLIGSQ--LPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRE--TLQENLENLMD 1039
Query: 690 IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
IHV+H R+P CA NG CSHLCL + PN SC CP G+ LL D + C
Sbjct: 1040 IHVFH-RRRPPVSTPCAMENGGCSHLCLRS----PNPSGFSCTCPTGINLLSDGKTC 1091
Score = 275 bits (674), Expect = 4e-73
Identities = 197/651 (30%), Positives = 288/651 (44%), Gaps = 54/651 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC+ +F C G+CI SW CD + DC D SDE C + C+E F C +G CI
Sbjct: 118 TCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRE--CEEDEFPC-QNGYCIR 172
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
W CD DC D SDE QC++ C +EF C G C+ W CD + DC DGSDE+
Sbjct: 173 SLWHCDGDNDCGDNSDE-QCDMRKCSDKEFRC--SDGSCIAEHWYCDGDTDCKDGSDEEN 229
Query: 142 CNET-----CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
C C +EF C G+CI + E C + F C G
Sbjct: 230 CPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSG 289
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
CI+A W CDGD DC D SDE C + S C + +F C+ CV +W
Sbjct: 290 LCINAGWRCDGDADCDDQSDERNCTT-----SMCTAEQFRCHSG-RCVRLSWRCDGEDDC 343
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E G+ C LDQF C + CI CNGV DC D SDE + Q+ +
Sbjct: 344 ADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDE---SPQQNCRPR 400
Query: 317 RTEFDC--GGGMCIPLSKVCDKHVDCPNFE----DEPRDRCGE-NECEKNNGGCSQRCVD 369
E +C G C ++ V C E C + NEC + G CSQ C +
Sbjct: 401 TGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAE-EGYCSQGCTN 459
Query: 370 TPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
+ + C CE GY+L D R+C+ + ++I I + + E Y +
Sbjct: 460 SEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSE----YTLLLNNL 515
Query: 429 TRCKATEGH--PSLLFARKHDIRKI------SLDHHEMVAIVNDTKSATALDYVFRTGMI 480
A + H L+F + +I + E+V+ ++ A+D+V +
Sbjct: 516 ENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVH--DKL 573
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIELSDL 539
+W+D +I A +D G R V++ + L +A+ + +YWTD G+ IE S +
Sbjct: 574 YWTDSGTSRIEVANLD-GAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 632
Query: 540 QGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWP 599
G+ R+I+ L P + ++ M+W D + IERA +DGSHR ++S + P
Sbjct: 633 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVD-AKHHVIERANLDGSHRKAVISQGLPHP 691
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHPFSITT 649
+T + +YW D +I+S N + G + +I + L P I T
Sbjct: 692 FAIT--VFEDSLYWTDWHTKSINSANKFTGKNQEIIRNK---LHFPMDIHT 737
Score = 260 bits (636), Expect = 2e-68
Identities = 140/350 (40%), Positives = 206/350 (58%), Gaps = 25/350 (7%)
Query: 400 GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---HH 456
G CS +C+ F C C TG +T + E + LLF+ + IR+ISLD H
Sbjct: 1366 GGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETY--LLFSSRGSIRRISLDTSDHT 1423
Query: 457 EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLA 516
++ V + + +LDY G ++++DV + I +A ++ G+ VIG L T+DGLA
Sbjct: 1424 DVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLN-GSNMETVIGRGLKTTDGLA 1482
Query: 517 VDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVP 576
VDWV +LYWTDTG N IE S L G+ RK+LI + L++ IA P +G++FWTDWG +
Sbjct: 1483 VDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDD---IAAFPRKGYLFWTDWGHIA 1539
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILH 636
KIERA +DGS R +++ D+ WPNGLTLD +R+YWVDA ++ I S + +G R++++
Sbjct: 1540 KIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVG 1599
Query: 637 STEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ HPF++T + W+YWTDW ++ R +K++G++ E + + ++ M I V P
Sbjct: 1600 H---VSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLA--NVEGLMDIIVVSPQ 1654
Query: 697 RQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
RQ G N C NG C+HLC F S V CACP+ PD Q C
Sbjct: 1655 RQ-TGTNACGVNNGGCTHLC-----FARASDFV-CACPDE----PDSQPC 1693
Score = 250 bits (611), Expect = 2e-65
Identities = 135/358 (37%), Positives = 202/358 (56%), Gaps = 22/358 (6%)
Query: 396 CA-DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
CA + G CS +C+ F C C TG +T L+FAR+ DIR +S
Sbjct: 1054 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSF--LIFARRIDIRMVS 1111
Query: 453 LD---HHEMVAIVNDT-KSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQ 508
LD ++V +N T K+ A+ + G ++WSD +I +A +D G+Q +I
Sbjct: 1112 LDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLD-GSQHEDIITTG 1170
Query: 509 LITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMF 568
L T+DGLAVD + +YWTDTG N IE+ +L G+MRK+L+ L+ PRAI L G+M+
Sbjct: 1171 LQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMY 1230
Query: 569 WTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
WTDWG+ K+ER+GMDGS R+ +++ ++ WPNGLT+D ++ W DA I + + +G
Sbjct: 1231 WTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNG 1290
Query: 629 SGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPM 688
+ R ++ ++HP+ +T + ++YWTDW +++RA+K G +V + S L M
Sbjct: 1291 ANRHTLV---SPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRS--NLPGLM 1345
Query: 689 VIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ QP G N C + NG CSHLCLP P SCACP G++L D + C
Sbjct: 1346 DMQAV-DRAQPLGFNKCGSRNGGCSHLCLPRP------SGFSCACPTGIQLKGDGKTC 1396
Score = 171 bits (415), Expect = 1e-41
Identities = 88/223 (39%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
R C EF C+ G CI W CD + DC D+SDE C K C + F C SDG CI
Sbjct: 156 RECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRK--CSDKEFRC-SDGSCI 209
Query: 81 PRSWRCDATADCPDGSDEHQC----EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
W CD DC DGSDE C C EEF C G C+ + CD + DC D
Sbjct: 210 AEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQC--AYGRCILDIYHCDGDDDCGDW 267
Query: 137 SDEKAC--NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT 194
SDE C ++ CRS EF C +G CI W E C T C + F C
Sbjct: 268 SDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAE-QFRCH 326
Query: 195 DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC 237
G+C+ W CDG+ DCAD SDE C +T + C +F C
Sbjct: 327 SGRCVRLSWRCDGEDDCADNSDEENCENTGSPQ--CALDQFLC 367
Score = 144 bits (348), Expect = 1e-33
Identities = 73/204 (35%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL 78
+ R C+ EFRC G CI W CD + DC D SDE+ C F+C + G
Sbjct: 192 DMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQC-AYGR 250
Query: 79 CIPRSWRCDATADCPDGSDEHQCEV-EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CI + CD DC D SDE C + C EF C G C+ W CD + DC D S
Sbjct: 251 CILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLCINAGWRCDGDADCDDQS 308
Query: 138 DEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ---SHFSC 193
DE+ C + C +++F C +G+C+++ W E C T PQ F C
Sbjct: 309 DERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCEN-TGSPQCALDQFLC 367
Query: 194 TDGQCISAWWHCDGDVDCADGSDE 217
+G+CI C+G DC D SDE
Sbjct: 368 WNGRCIGQRKLCNGVNDCGDNSDE 391
Score = 107 bits (256), Expect = 2e-22
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 15/150 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S + C S EF C +G CI W+CD + DC D SDE CT + +C +F C S G
Sbjct: 274 SSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDE--RNCTTS--MCTAEQFRCHS-G 328
Query: 78 LCIPRSWRCDATADCPDGSDEHQCE---VEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
C+ SWRCD DC D SDE CE C ++F C G C+ +C+ DC
Sbjct: 329 RCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWN--GRCIGQRKLCNGVNDCG 386
Query: 135 DGSDEKACNETC--RSDEFTC--GNGKCIQ 160
D SDE + C R+ E C NG C Q
Sbjct: 387 DNSDESP-QQNCRPRTGEENCNVNNGGCAQ 415
Score = 105 bits (252), Expect = 6e-22
Identities = 76/285 (26%), Positives = 130/285 (45%), Gaps = 13/285 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDECADPGSCSQIC 406
R G+N C NNGGC+ C+ + Y C C G++ I + C + +D+ I
Sbjct: 742 RQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIR 801
Query: 407 INEKGTFKCECHTGYARDPRDRTRC--KATEGHPSLLFARKHDIRKISLDHHEMVAIVN- 463
T D R + + H I + D +V+
Sbjct: 802 RISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT 861
Query: 464 --DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVY 521
++ + A+D+V T ++W+D ++I A D G+ RTV+I E L + V+ +
Sbjct: 862 SLESPAGLAIDWV--TNKLYWTDAGTDRIEVANTD-GSMRTVLIWENLDRPRDIVVEPMG 918
Query: 522 NHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIER 580
++YWTD G + IE + + + R+++I L P +A++ ++W D G + IE
Sbjct: 919 GYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAG-MKTIEF 977
Query: 581 AGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
AG+DGS R ++ + P GLT L +R+YW D + +I S +
Sbjct: 978 AGLDGSKRKVLIGSQLPHPFGLT--LYGERIYWTDWQTKSIQSAD 1020
Score = 93.1 bits (221), Expect = 3e-18
Identities = 82/301 (27%), Positives = 134/301 (44%), Gaps = 23/301 (7%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC----ADPGSCSQIC 406
G N+C NGGCS C+ P G+ C C G +L D +TC+ E + GS +I
Sbjct: 1357 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRIS 1416
Query: 407 INEKGTFKCECHTGYAR-DPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN-- 463
++ + H + + +G IR+ L+ M ++
Sbjct: 1417 LDTSD--HTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRG 1474
Query: 464 -DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYN 522
T A+D+V R ++W+D I + +D G+ R V+I L D +A
Sbjct: 1475 LKTTDGLAVDWVARN--LYWTDTGRNTIEASRLD-GSCRKVLINNSL---DDIAAFPRKG 1528
Query: 523 HLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERA 581
+L+WTD GH IE ++L G+ RK+LI L P + L+ ++W D + +IE A
Sbjct: 1529 YLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVD-AHLDRIESA 1587
Query: 582 GMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEV 640
++G R +V + V P LT + +YW D + +I + Y G + +L + E
Sbjct: 1588 DLNGKLRQVLVGH-VSHPFALTQQ--DRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEG 1644
Query: 641 L 641
L
Sbjct: 1645 L 1645
Score = 92.3 bits (219), Expect = 6e-18
Identities = 80/298 (26%), Positives = 132/298 (44%), Gaps = 33/298 (11%)
Query: 356 CEKNNGGCSQRCV--DTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
C NGGCS C+ P G+ C C G L+ D +TC PG S + +
Sbjct: 1054 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTC-------SPGMNSFLIFARRID 1106
Query: 413 FK-CECHTGYARD---PRDRTR-------CKATEGHPSLLFARKHDIRKISLD---HHEM 458
+ Y D P + T EG + H I + +LD H ++
Sbjct: 1107 IRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDI 1166
Query: 459 VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ T A+D + R ++W+D +I +D G+ R V++ + L + + +
Sbjct: 1167 ITTGLQTTDGLAVDAIGR--KVYWTDTGTNRIEVGNLD-GSMRKVLVWQNLDSPRAIVLY 1223
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+YWTD G N +E S + G+ R +LI + L P + ++ + W D +
Sbjct: 1224 HEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWAD-AHTER 1282
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A ++G++R T+VS V+ P GLT L+ +YW D + +I + G+G +IL
Sbjct: 1283 IEAADLNGANRHTLVS-PVQHPYGLT--LLDSYIYWTDWQTRSIHRAD-KGTGSNVIL 1336
Score = 33.1 bits (72), Expect = 3.8
Identities = 12/32 (37%), Positives = 16/32 (50%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDC 378
P+ + G N C NNGGC+ C + C C
Sbjct: 1653 PQRQTGTNACGVNNGGCTHLCFARASDFVCAC 1684
>AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein
receptor-related protein 10 protein.
Length = 1905
Score = 584 bits (1443), Expect = e-166
Identities = 299/730 (40%), Positives = 394/730 (53%), Gaps = 41/730 (5%)
Query: 23 CTSSEFRCKTGR-----CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
C S F C CIP W+CD + DC D SDED + C F C +G
Sbjct: 27 CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPT----CSPLDFHC-DNG 81
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CI RSW CD DC D SDE C C +EF C+ G C+ W CD + DC D S
Sbjct: 82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQN--GYCIRSLWHCDGDNDCGDNS 139
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH---FSCT 194
DE+ C EF C +G CI W E CP+ P + F C
Sbjct: 140 DEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCA 199
Query: 195 DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXX 254
G+CI +HCDGD DC D SDE C S PC S EF C+ + C++ W
Sbjct: 200 YGRCILDIYHCDGDDDCGDWSDESDCSS----HQPCRSGEFMCDSGL-CINAGWRCDGDA 254
Query: 255 XXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTIC 314
E C ++ C +QF+C C+ + C+G DC D SDE NC +
Sbjct: 255 DCDDQSDE--RNCTTSM-CTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQ 311
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC----GENECEKNNGGCSQRCVD 369
+F C G CI K+C+ DC + DE P+ C GE C NNGGC+Q+C
Sbjct: 312 CALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQM 371
Query: 370 TPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
C C GY+L D TC+D++ECA+ G CSQ C N +G F+C C TGY P DR
Sbjct: 372 VRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRP-DR 430
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDE 488
CKA P LLFA + DIR++ E ++N+ ++A ALD+ R ++FWSDV +
Sbjct: 431 RSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLD 490
Query: 489 KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILI 548
+I +A ++ G+ V+ L + GLAVDWV++ LYWTD+G + IE+++L G RK+L+
Sbjct: 491 RILRANLN-GSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLL 549
Query: 549 RDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
LE+PRAIAL+P+EG ++WTDWG P+IE + MDGS R I + WPNGLT+D
Sbjct: 550 WQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAG 609
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+R+YWVDAK + I N DGS R+ ++ ++ L HPF+IT FED +YWTDW ++ AN
Sbjct: 610 RRMYWVDAKHHVIERANLDGSHRKAVI--SQGLPHPFAITVFEDSLYWTDWHTKSINSAN 667
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPR 728
KF GK+ E I + L PM IH HP RQP G N C NG C+HLCLP+ G N
Sbjct: 668 KFTGKNQEII--RNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPS---GQN--- 719
Query: 729 VSCACPNGLK 738
+CACP G +
Sbjct: 720 YTCACPTGFR 729
Score = 293 bits (720), Expect = 1e-78
Identities = 150/357 (42%), Positives = 210/357 (58%), Gaps = 17/357 (4%)
Query: 394 DECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
+ C D G C+ +C+ + C C TG+ + + A LLFAR+ DIR+IS
Sbjct: 700 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRKIS---SHACAQSLDKFLLFARRMDIRRIS 756
Query: 453 LDHHEM---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQL 509
D ++ V + D +SA ALD+ R ++W+DV+ + I +A D GT + VV+ L
Sbjct: 757 FDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWD-GTGQEVVVDTSL 815
Query: 510 ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFW 569
+ GLA+DWV N LYWTD G + IE+++ G+MR +LI + L+ PR I + P+ G+M+W
Sbjct: 816 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 875
Query: 570 TDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGS 629
TDWG PKIERAGMD S R I+S ++ WPNGL +D QR+YW DA M TI DGS
Sbjct: 876 TDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGS 935
Query: 630 GRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMV 689
R++++ S L HPF +T + + +YWTDW ++ A++ G D E T L+N M
Sbjct: 936 KRKVLIGSQ--LPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRE--TLQENLENLMD 991
Query: 690 IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
IHV+H R+P CA NG CSHLCL + PN SC CP G+ LL D + C
Sbjct: 992 IHVFH-RRRPPVSTPCAMENGGCSHLCLRS----PNPSGFSCTCPTGINLLSDGKTC 1043
Score = 275 bits (674), Expect = 4e-73
Identities = 197/651 (30%), Positives = 288/651 (44%), Gaps = 54/651 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC+ +F C G+CI SW CD + DC D SDE C + C+E F C +G CI
Sbjct: 70 TCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQD--CPPRE--CEEDEFPC-QNGYCIR 124
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
W CD DC D SDE QC++ C +EF C G C+ W CD + DC DGSDE+
Sbjct: 125 SLWHCDGDNDCGDNSDE-QCDMRKCSDKEFRC--SDGSCIAEHWYCDGDTDCKDGSDEEN 181
Query: 142 CNET-----CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
C C +EF C G+CI + E C + F C G
Sbjct: 182 CPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSG 241
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
CI+A W CDGD DC D SDE C + S C + +F C+ CV +W
Sbjct: 242 LCINAGWRCDGDADCDDQSDERNCTT-----SMCTAEQFRCHSG-RCVRLSWRCDGEDDC 295
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E G+ C LDQF C + CI CNGV DC D SDE + Q+ +
Sbjct: 296 ADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDE---SPQQNCRPR 352
Query: 317 RTEFDC--GGGMCIPLSKVCDKHVDCPNFE----DEPRDRCGE-NECEKNNGGCSQRCVD 369
E +C G C ++ V C E C + NEC + G CSQ C +
Sbjct: 353 TGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAE-EGYCSQGCTN 411
Query: 370 TPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
+ + C CE GY+L D R+C+ + ++I I + + E Y +
Sbjct: 412 SEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSE----YTLLLNNL 467
Query: 429 TRCKATEGH--PSLLFARKHDIRKI------SLDHHEMVAIVNDTKSATALDYVFRTGMI 480
A + H L+F + +I + E+V+ ++ A+D+V +
Sbjct: 468 ENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVH--DKL 525
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIELSDL 539
+W+D +I A +D G R V++ + L +A+ + +YWTD G+ IE S +
Sbjct: 526 YWTDSGTSRIEVANLD-GAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSM 584
Query: 540 QGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWP 599
G+ R+I+ L P + ++ M+W D + IERA +DGSHR ++S + P
Sbjct: 585 DGSGRRIIADTHLFWPNGLTIDYAGRRMYWVD-AKHHVIERANLDGSHRKAVISQGLPHP 643
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHPFSITT 649
+T + +YW D +I+S N + G + +I + L P I T
Sbjct: 644 FAIT--VFEDSLYWTDWHTKSINSANKFTGKNQEIIRNK---LHFPMDIHT 689
Score = 274 bits (672), Expect = 8e-73
Identities = 144/350 (41%), Positives = 210/350 (60%), Gaps = 22/350 (6%)
Query: 400 GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---HH 456
G CS +C+ F C C TG +T + E + LLF+ + IR+ISLD H
Sbjct: 1318 GGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETY--LLFSSRGSIRRISLDTSDHT 1375
Query: 457 EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLA 516
++ V + + +LDY G ++++DV + I +A ++ G+ VIG L T+DGLA
Sbjct: 1376 DVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLN-GSNMETVIGRGLKTTDGLA 1434
Query: 517 VDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVP 576
VDWV +LYWTDTG N IE S L G+ RK+LI + L+EPRAIA+ P +G++FWTDWG +
Sbjct: 1435 VDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA 1494
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILH 636
KIERA +DGS R +++ D+ WPNGLTLD +R+YWVDA ++ I S + +G R++++
Sbjct: 1495 KIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVG 1554
Query: 637 STEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ HPF++T + W+YWTDW ++ R +K++G++ E + + ++ M I V P
Sbjct: 1555 H---VSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLA--NVEGLMDIIVVSPQ 1609
Query: 697 RQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
RQ G N C NG C+HLC F S V CACP+ PD Q C
Sbjct: 1610 RQ-TGTNACGVNNGGCTHLC-----FARASDFV-CACPDE----PDSQPC 1648
Score = 250 bits (611), Expect = 2e-65
Identities = 135/358 (37%), Positives = 202/358 (56%), Gaps = 22/358 (6%)
Query: 396 CA-DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
CA + G CS +C+ F C C TG +T L+FAR+ DIR +S
Sbjct: 1006 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSF--LIFARRIDIRMVS 1063
Query: 453 LD---HHEMVAIVNDT-KSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQ 508
LD ++V +N T K+ A+ + G ++WSD +I +A +D G+Q +I
Sbjct: 1064 LDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLD-GSQHEDIITTG 1122
Query: 509 LITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMF 568
L T+DGLAVD + +YWTDTG N IE+ +L G+MRK+L+ L+ PRAI L G+M+
Sbjct: 1123 LQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMY 1182
Query: 569 WTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
WTDWG+ K+ER+GMDGS R+ +++ ++ WPNGLT+D ++ W DA I + + +G
Sbjct: 1183 WTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNG 1242
Query: 629 SGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPM 688
+ R ++ ++HP+ +T + ++YWTDW +++RA+K G +V + S L M
Sbjct: 1243 ANRHTLV---SPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRS--NLPGLM 1297
Query: 689 VIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ QP G N C + NG CSHLCLP P SCACP G++L D + C
Sbjct: 1298 DMQAV-DRAQPLGFNKCGSRNGGCSHLCLPRP------SGFSCACPTGIQLKGDGKTC 1348
Score = 171 bits (415), Expect = 1e-41
Identities = 88/223 (39%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
R C EF C+ G CI W CD + DC D+SDE C K C + F C SDG CI
Sbjct: 108 RECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQ---CDMRK--CSDKEFRC-SDGSCI 161
Query: 81 PRSWRCDATADCPDGSDEHQC----EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
W CD DC DGSDE C C EEF C G C+ + CD + DC D
Sbjct: 162 AEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQC--AYGRCILDIYHCDGDDDCGDW 219
Query: 137 SDEKAC--NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT 194
SDE C ++ CRS EF C +G CI W E C T C + F C
Sbjct: 220 SDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAE-QFRCH 278
Query: 195 DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC 237
G+C+ W CDG+ DCAD SDE C +T + C +F C
Sbjct: 279 SGRCVRLSWRCDGEDDCADNSDEENCENTGSPQ--CALDQFLC 319
Score = 144 bits (348), Expect = 1e-33
Identities = 73/204 (35%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL 78
+ R C+ EFRC G CI W CD + DC D SDE+ C F+C + G
Sbjct: 144 DMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQC-AYGR 202
Query: 79 CIPRSWRCDATADCPDGSDEHQCEV-EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CI + CD DC D SDE C + C EF C G C+ W CD + DC D S
Sbjct: 203 CILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMC--DSGLCINAGWRCDGDADCDDQS 260
Query: 138 DEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ---SHFSC 193
DE+ C + C +++F C +G+C+++ W E C T PQ F C
Sbjct: 261 DERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCEN-TGSPQCALDQFLC 319
Query: 194 TDGQCISAWWHCDGDVDCADGSDE 217
+G+CI C+G DC D SDE
Sbjct: 320 WNGRCIGQRKLCNGVNDCGDNSDE 343
Score = 107 bits (256), Expect = 2e-22
Identities = 59/150 (39%), Positives = 74/150 (49%), Gaps = 15/150 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S + C S EF C +G CI W+CD + DC D SDE CT + +C +F C S G
Sbjct: 226 SSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDE--RNCTTS--MCTAEQFRCHS-G 280
Query: 78 LCIPRSWRCDATADCPDGSDEHQCE---VEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
C+ SWRCD DC D SDE CE C ++F C G C+ +C+ DC
Sbjct: 281 RCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWN--GRCIGQRKLCNGVNDCG 338
Query: 135 DGSDEKACNETC--RSDEFTC--GNGKCIQ 160
D SDE + C R+ E C NG C Q
Sbjct: 339 DNSDESP-QQNCRPRTGEENCNVNNGGCAQ 367
Score = 105 bits (252), Expect = 6e-22
Identities = 76/285 (26%), Positives = 130/285 (45%), Gaps = 13/285 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDECADPGSCSQIC 406
R G+N C NNGGC+ C+ + Y C C G++ I + C + +D+ I
Sbjct: 694 RQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIR 753
Query: 407 INEKGTFKCECHTGYARDPRDRTRC--KATEGHPSLLFARKHDIRKISLDHHEMVAIVN- 463
T D R + + H I + D +V+
Sbjct: 754 RISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT 813
Query: 464 --DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVY 521
++ + A+D+V T ++W+D ++I A D G+ RTV+I E L + V+ +
Sbjct: 814 SLESPAGLAIDWV--TNKLYWTDAGTDRIEVANTD-GSMRTVLIWENLDRPRDIVVEPMG 870
Query: 522 NHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIER 580
++YWTD G + IE + + + R+++I L P +A++ ++W D G + IE
Sbjct: 871 GYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAG-MKTIEF 929
Query: 581 AGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
AG+DGS R ++ + P GLT L +R+YW D + +I S +
Sbjct: 930 AGLDGSKRKVLIGSQLPHPFGLT--LYGERIYWTDWQTKSIQSAD 972
Score = 95.9 bits (228), Expect = 5e-19
Identities = 82/301 (27%), Positives = 134/301 (44%), Gaps = 20/301 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC----ADPGSCSQIC 406
G N+C NGGCS C+ P G+ C C G +L D +TC+ E + GS +I
Sbjct: 1309 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRIS 1368
Query: 407 INEKGTFKCECHTGYAR-DPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN-- 463
++ + H + + +G IR+ L+ M ++
Sbjct: 1369 LDTSD--HTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRG 1426
Query: 464 -DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYN 522
T A+D+V R ++W+D I + +D G+ R V+I L +AV
Sbjct: 1427 LKTTDGLAVDWVARN--LYWTDTGRNTIEASRLD-GSCRKVLINNSLDEPRAIAVFPRKG 1483
Query: 523 HLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERA 581
+L+WTD GH IE ++L G+ RK+LI L P + L+ ++W D + +IE A
Sbjct: 1484 YLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVD-AHLDRIESA 1542
Query: 582 GMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEV 640
++G R +V + V P LT + +YW D + +I + Y G + +L + E
Sbjct: 1543 DLNGKLRQVLVGH-VSHPFALTQQ--DRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEG 1599
Query: 641 L 641
L
Sbjct: 1600 L 1600
Score = 92.3 bits (219), Expect = 6e-18
Identities = 80/298 (26%), Positives = 132/298 (44%), Gaps = 33/298 (11%)
Query: 356 CEKNNGGCSQRCV--DTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
C NGGCS C+ P G+ C C G L+ D +TC PG S + +
Sbjct: 1006 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTC-------SPGMNSFLIFARRID 1058
Query: 413 FK-CECHTGYARD---PRDRTR-------CKATEGHPSLLFARKHDIRKISLD---HHEM 458
+ Y D P + T EG + H I + +LD H ++
Sbjct: 1059 IRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDI 1118
Query: 459 VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ T A+D + R ++W+D +I +D G+ R V++ + L + + +
Sbjct: 1119 ITTGLQTTDGLAVDAIGR--KVYWTDTGTNRIEVGNLD-GSMRKVLVWQNLDSPRAIVLY 1175
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+YWTD G N +E S + G+ R +LI + L P + ++ + W D +
Sbjct: 1176 HEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWAD-AHTER 1234
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A ++G++R T+VS V+ P GLT L+ +YW D + +I + G+G +IL
Sbjct: 1235 IEAADLNGANRHTLVS-PVQHPYGLT--LLDSYIYWTDWQTRSIHRAD-KGTGSNVIL 1288
Score = 33.1 bits (72), Expect = 3.8
Identities = 12/32 (37%), Positives = 16/32 (50%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDC 378
P+ + G N C NNGGC+ C + C C
Sbjct: 1608 PQRQTGTNACGVNNGGCTHLCFARASDFVCAC 1639
>BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 573 bits (1414), Expect = e-163
Identities = 281/704 (39%), Positives = 395/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCRL-DQFQCKDHSCIPGA 289
C+ WV EA ELC C QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F +H++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 270 bits (663), Expect = 9e-72
Identities = 195/662 (29%), Positives = 288/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + +++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAAGKSPSLIFTNRHEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 963
Score = 573 bits (1414), Expect = e-163
Identities = 281/704 (39%), Positives = 395/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCRL-DQFQCKDHSCIPGA 289
C+ WV EA ELC C QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F +H++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 270 bits (663), Expect = 9e-72
Identities = 195/662 (29%), Positives = 288/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + +++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAAGKSPSLIFTNRHEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 573 bits (1414), Expect = e-163
Identities = 281/704 (39%), Positives = 395/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCRL-DQFQCKDHSCIPGA 289
C+ WV EA ELC C QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F +H++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 270 bits (663), Expect = 9e-72
Identities = 195/662 (29%), Positives = 288/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + +++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAAGKSPSLIFTNRHEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 573 bits (1414), Expect = e-163
Identities = 281/704 (39%), Positives = 395/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCRL-DQFQCKDHSCIPGA 289
C+ WV EA ELC C QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F +H++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 270 bits (663), Expect = 9e-72
Identities = 195/662 (29%), Positives = 288/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + +++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAAGKSPSLIFTNRHEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 963
Score = 573 bits (1414), Expect = e-163
Identities = 281/704 (39%), Positives = 395/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCRL-DQFQCKDHSCIPGA 289
C+ WV EA ELC C QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F +H++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 270 bits (663), Expect = 9e-72
Identities = 195/662 (29%), Positives = 288/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + +++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAAGKSPSLIFTNRHEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein.
Length = 963
Score = 571 bits (1409), Expect = e-162
Identities = 280/704 (39%), Positives = 396/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCR-LDQFQCKDHSCIPGA 289
C+ WV EA ELC C + QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATVSQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F ++++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAGGKSPSLIFTNRYEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 269 bits (660), Expect = 2e-71
Identities = 195/662 (29%), Positives = 287/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + ++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATVSQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAGGKSPSLIFTNRYEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor 2
precursor protein.
Length = 963
Score = 571 bits (1409), Expect = e-162
Identities = 280/704 (39%), Positives = 396/704 (56%), Gaps = 39/704 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C++ +F+C ++ CIP WRCD DC D SDE C + C +FTC G C+ W
Sbjct: 47 CEKDQFQCRNER-CIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDN--GHCIHERW 103
Query: 126 MCDDNPDCSDGSDEK--ACN-ETCRSDEFTCG--NGKCIQMRWVXXXXXXXXXXXXEVKC 180
CD +C DGSDE C + C +++ +CG + KC+ W E C
Sbjct: 104 KCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC--N 238
T C P F C + C++A + CDGD DC DGSDE GC C EF C +
Sbjct: 164 AT-LCAPHE-FQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPA-----CGPREFRCGGD 216
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELC--------RGNVTCR-LDQFQCKDHSCIPGA 289
C+ WV EA ELC C + QF C+ C+
Sbjct: 217 GGGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATVSQFACRSGECVHLG 276
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD 349
C+G +DC D SDE +C D EF CG G C+ K C++ DCP+ DE
Sbjct: 277 WRCDGDRDCKDKSDEADCPLGTCRGD---EFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 350 RCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINE 409
G NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N
Sbjct: 334 LQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNY 393
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
KG FKCEC+ GY D + CKA G PSL+F ++++R+I L ++ K+
Sbjct: 394 KGYFKCECYPGYEMDLLTKN-CKAAGGKSPSLIFTNRYEVRRIDLVKRNYSRLIPMLKNV 452
Query: 469 TALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLY 525
ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+Y
Sbjct: 453 VALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIY 512
Query: 526 WTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
WTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G
Sbjct: 513 WTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNG 572
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPF 645
R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF
Sbjct: 573 VDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPF 632
Query: 646 SITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC 705
I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C
Sbjct: 633 GIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDAC 690
Query: 706 ---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 691 ELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 734
Score = 269 bits (660), Expect = 2e-71
Identities = 195/662 (29%), Positives = 287/662 (43%), Gaps = 54/662 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC---T 194
DE C C EF CGN C+ +V E C P C P+ F C
Sbjct: 159 DEAGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPR-EFRCGGDG 217
Query: 195 DGQCISAWWHCDGDVDCADGSDEV-------GCVSTPKVRSPCISTEFECNDRITCVHRA 247
G CI W CD DC D SDE G +T + ++F C CVH
Sbjct: 218 GGACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATVSQFACRSG-ECVHLG 276
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W EA + G TCR D+FQC D +C+ +CN +DCPDGSDE C
Sbjct: 277 WRCDGDRDCKDKSDEA-DCPLG--TCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDRCGE-NECEKNNGGCSQ 365
+ C GG I CP F+ + CG+ +EC K+ CSQ
Sbjct: 334 LQGLNECLHNN----GGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDEC-KDPDACSQ 388
Query: 366 RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCE-CHTGYAR 423
CV+ + C+C GY++ + + C + A S S I N + + Y+R
Sbjct: 389 ICVNYKGYFKCECYPGYEMDLLTKNC----KAAGGKSPSLIFTNRYEVRRIDLVKRNYSR 444
Query: 424 --DPRDRTRCKATEGHPSLLFARKHDIRKI-------SLDHHEMVAIVND---TKSATAL 471
E + ++ RKI + D E ++++ + A+
Sbjct: 445 LIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAV 504
Query: 472 DYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
D+V + I+W+D ++ I A +D G +RT + L +AVD + +YW+D G
Sbjct: 505 DWVHK--HIYWTDSGNKTISVATVDGGRRRT-LFSRNLSEPRAIAVDPLRGFMYWSDWGD 561
Query: 532 N-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
IE S L G R+ L+ D +E P I L+ L ++W D ++ ++ G +R T
Sbjct: 562 QAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVD-SKLHQLSSIDFSGGNRKT 620
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
++S + + + +V+W D + I S N IL E L +P I F
Sbjct: 621 LISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIF 678
Query: 651 ED 652
+
Sbjct: 679 HE 680
>AL450467-2|CAH72453.1| 752|Homo sapiens very low density
lipoprotein receptor protein.
Length = 752
Score = 547 bits (1351), Expect = e-155
Identities = 256/605 (42%), Positives = 349/605 (57%), Gaps = 13/605 (2%)
Query: 146 CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHC 205
C +F C NG+CI + W E+ C PTC F C+ CI W C
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDELDCAPPTCGAHE-FQCSTSSCIPISWVC 91
Query: 206 DGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA 263
D D DC+D SDE C P + + C ++E +C C+H+ W E
Sbjct: 92 DDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCKDGSDEV 150
Query: 264 LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG 323
C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C +F C
Sbjct: 151 N--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGPGKFKCR 206
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CDC G++
Sbjct: 207 SGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFE 266
Query: 384 LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFA 443
LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA PSL+F
Sbjct: 267 LIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKEPSLIFT 325
Query: 444 RKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTV 503
+ DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+ R V
Sbjct: 326 NRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHV 385
Query: 504 VIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ + + +AVDWVY +YWTD I ++ L G RK L L EP +IA++PL
Sbjct: 386 KMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPL 445
Query: 564 EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISS 623
G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K++ +SS
Sbjct: 446 SGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSS 505
Query: 624 CNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHT 683
+ +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E T +
Sbjct: 506 VDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--ELATLVNN 563
Query: 684 LQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLP 741
L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+G +
Sbjct: 564 LNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPSGYNVEE 623
Query: 742 DDQMC 746
+ + C
Sbjct: 624 NGRDC 628
Score = 153 bits (370), Expect = 3e-36
Identities = 82/204 (40%), Positives = 97/204 (47%), Gaps = 16/204 (7%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE C + F+C S CIP
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDE----LDCAPPTCGAHEFQC-STSSCIPI 87
Query: 83 SWRCDATADCPDGSDE--HQCEVE-----ACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
SW CD ADC D SDE QC + C E C GEC+ W CD +PDC D
Sbjct: 88 SWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGS--GECIHKKWRCDGDPDCKD 145
Query: 136 GSDEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQSHFSC 193
GSDE C + TCR D+F C +G CI EV C C F C
Sbjct: 146 GSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC 205
Query: 194 TDGQCISAWWHCDGDVDCADGSDE 217
G+CI C+ + DC D SDE
Sbjct: 206 RSGECIDISKVCNQEQDCRDWSDE 229
Score = 128 bits (310), Expect = 6e-29
Identities = 59/146 (40%), Positives = 79/146 (54%), Gaps = 9/146 (6%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV---CQEYRFECLSDGL 78
TC + EF+C T CIP+SW CD++ DCSD SDE C ++ C +C G
Sbjct: 71 TCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQC-GSGE 129
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
CI + WRCD DC DGSDE C C P++F C + G C+ + C+ DC DGSD
Sbjct: 130 CIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFEC--EDGSCIHGSRQCNGIRDCVDGSD 187
Query: 139 EKAC---NETCRSDEFTCGNGKCIQM 161
E C N+ +F C +G+CI +
Sbjct: 188 EVNCKNVNQCLGPGKFKCRSGECIDI 213
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 154 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 210
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 211 IDISKVCNQEQDCRDWSDEPLKECHINEC 239
>AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ35062 fis, clone OCBBF2019195, highly similar to
VERY LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR. ).
Length = 752
Score = 547 bits (1351), Expect = e-155
Identities = 256/605 (42%), Positives = 349/605 (57%), Gaps = 13/605 (2%)
Query: 146 CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHC 205
C +F C NG+CI + W E+ C PTC F C+ CI W C
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDELDCAPPTCGAHE-FQCSTSSCIPISWVC 91
Query: 206 DGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA 263
D D DC+D SDE C P + + C ++E +C C+H+ W E
Sbjct: 92 DDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCKDGSDEV 150
Query: 264 LELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG 323
C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C +F C
Sbjct: 151 N--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGPGKFKCR 206
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CDC G++
Sbjct: 207 SGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFE 266
Query: 384 LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFA 443
LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA PSL+F
Sbjct: 267 LIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKEPSLIFT 325
Query: 444 RKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTV 503
+ DIRKI L+ E + +V ++ ALD +FW+D++ + I+ A ID+ R V
Sbjct: 326 NRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHV 385
Query: 504 VIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ + + +AVDWVY +YWTD I ++ L G RK L L EP +IA++PL
Sbjct: 386 KMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPL 445
Query: 564 EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISS 623
G+++W+DWG+ KIE+AGM+G R +V+ D++WPNG+TLDL++ R+YW+D+K++ +SS
Sbjct: 446 SGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSS 505
Query: 624 CNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHT 683
+ +G RR++L S E L HP ++T FED VYW D + AVY ANKF G E T +
Sbjct: 506 VDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGS--ELATLVNN 563
Query: 684 LQNPMVIHVYHPYRQPDGVNHCA--AVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLP 741
L + I VYH QP G N C NG C +LCLPAP+ +SP+ +C+CP+G +
Sbjct: 564 LNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPSGYNVEE 623
Query: 742 DDQMC 746
+ + C
Sbjct: 624 NGRDC 628
Score = 153 bits (370), Expect = 3e-36
Identities = 82/204 (40%), Positives = 97/204 (47%), Gaps = 16/204 (7%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE C + F+C S CIP
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDE----LDCAPPTCGAHEFQC-STSSCIPI 87
Query: 83 SWRCDATADCPDGSDE--HQCEVE-----ACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
SW CD ADC D SDE QC + C E C GEC+ W CD +PDC D
Sbjct: 88 SWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGS--GECIHKKWRCDGDPDCKD 145
Query: 136 GSDEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT-CQPQSHFSC 193
GSDE C + TCR D+F C +G CI EV C C F C
Sbjct: 146 GSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC 205
Query: 194 TDGQCISAWWHCDGDVDCADGSDE 217
G+CI C+ + DC D SDE
Sbjct: 206 RSGECIDISKVCNQEQDCRDWSDE 229
Score = 128 bits (310), Expect = 6e-29
Identities = 59/146 (40%), Positives = 79/146 (54%), Gaps = 9/146 (6%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV---CQEYRFECLSDGL 78
TC + EF+C T CIP+SW CD++ DCSD SDE C ++ C +C G
Sbjct: 71 TCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQC-GSGE 129
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
CI + WRCD DC DGSDE C C P++F C + G C+ + C+ DC DGSD
Sbjct: 130 CIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFEC--EDGSCIHGSRQCNGIRDCVDGSD 187
Query: 139 EKAC---NETCRSDEFTCGNGKCIQM 161
E C N+ +F C +G+CI +
Sbjct: 188 EVNCKNVNQCLGPGKFKCRSGECIDI 213
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 154 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 210
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 211 IDISKVCNQEQDCRDWSDEPLKECHINEC 239
>U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.
Length = 4655
Score = 539 bits (1330), Expect = e-152
Identities = 290/742 (39%), Positives = 388/742 (52%), Gaps = 35/742 (4%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C F CK GRC+P + CD DC D+SDE +C C F C G CIP
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQ--LCGTLNNTCSSSAFTC-GHGECIPA 1082
Query: 83 SWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
WRCD DC DGSDEH C A C ++TC +C+ W+CD + DC DGSDE
Sbjct: 1083 HWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNH--QCISKNWVCDTDNDCGDGSDE 1140
Query: 140 KACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG- 196
K CN ETC+ +F C N +CI + +V EV C C S F C G
Sbjct: 1141 KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVL-NCTA-SQFKCASGD 1198
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+CI CDG DC+D SDE GC + P C S EF+C + C+ W
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPP--GMCHSDEFQCQEDGICIPNFWECDGHPDC 1256
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E C TC F C + +CI A C+ DC D SDE +C Q C
Sbjct: 1257 LYGSDEH-NACVPK-TCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPS 1314
Query: 317 RTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
++ C G +C+ LS VCD DCPN DE C N C NGGC+ CV P G
Sbjct: 1315 -WQWQCLGHNICVNLSVVCDGIFDCPNGTDES-PLCNGNSCSDFNGGCTHECVQEPFGAK 1372
Query: 376 CDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
C C G+ L D++TCEDIDEC GSCSQ C N +G+F+C C TGY + RT CK T
Sbjct: 1373 CLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRT-CKVT 1431
Query: 435 EGHPSLLFARKHD---IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIY 491
LL + ++ H + ++V + A+D+ +G IFWSD K +
Sbjct: 1432 ASESLLLLVASQNKIIADSVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTW 1491
Query: 492 KAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDR 551
A GT R VV +I ++ +A+DWV +LYWTD IE+S + G+ R +LI
Sbjct: 1492 SA-FQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKN 1550
Query: 552 LEEPRAIALNPL--EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQ 609
L PR +AL+P E +FW+DWG P+IERA MDGS R+ IV + WP GLT+D +
Sbjct: 1551 LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNR 1610
Query: 610 RVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANK 669
+Y++D+ ++ + C+Y+G RR ++ S ++RHP+++T FED VYWTD V RANK
Sbjct: 1611 LLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANK 1670
Query: 670 FNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRV 729
++G + + + +Q P+ I HP +QP+ VN CA CSHLCL + + GP+
Sbjct: 1671 WHGGNQSVV--MYNIQWPLGIVAVHPSKQPNSVNPCAF--SRCSHLCLLSSQ-GPHF--Y 1723
Query: 730 SCACPNGLKLLPDDQMCVEDSK 751
SC CP+G L PD C+ D +
Sbjct: 1724 SCVCPSGWSLSPDLLNCLRDDQ 1745
Score = 485 bits (1196), Expect = e-136
Identities = 266/748 (35%), Positives = 374/748 (50%), Gaps = 53/748 (7%)
Query: 21 RTCTSS-EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R C ++ EF C RCIP + C+ +C D++ D C CQ +C + +C
Sbjct: 2778 RDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCP--DRTCQSGYTKCHNSNIC 2835
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
IPR + CD DC D SDE+ C C EF C G C+P W CD DC D S
Sbjct: 2836 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS--GRCIPQHWYCDQETDCFDAS 2893
Query: 138 DEKA-CNE---TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK---CPTPTCQPQSH 190
DE A C TC +DEF C G+CI W+ E K C C S
Sbjct: 2894 DEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS-DSE 2952
Query: 191 FSCT-----DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D +CI W CDGDVDC DG DE + R C EF C + C+
Sbjct: 2953 FLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDE----NQNCTRRTCSENEFTCGYGL-CIP 3007
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE- 304
+ + E L + TC+ +QF C++ CI C+ DC DGSDE
Sbjct: 3008 KIFRCDRHNDCGDYSDERGCLYQ---TCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDEL 3064
Query: 305 -YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGG 362
+ C + C EF C G CI + K+C+ DC + DE CG NEC + + G
Sbjct: 3065 MHLCHTPEPTCPPH-EFKCDNGRCIEMMKLCNHLDDCLDNSDEKG--CGINECHDPSISG 3121
Query: 363 CSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTG 420
C C DT +YC C GYKL+ D RTC DIDEC + P CSQ C N G++ C+C G
Sbjct: 3122 CDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPG 3181
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMI 480
Y R+P +T + + P L+F+ ++ +R +++D + I+ + ALD+ +
Sbjct: 3182 YLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRL 3241
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
+W D + I + +++ T + +I +L ++ LAVDWV LYW D + + +SDL
Sbjct: 3242 YWIDTQRQVIERMFLNK-TNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLN 3300
Query: 541 GNMRKILIRDRLE--------EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
G R++L + ++ PR +AL+P G+++W DWG I R GMDG+++S I+
Sbjct: 3301 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVII 3360
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S ++WPNG+T+D +YW DA + I + +G R + L HPF+IT FED
Sbjct: 3361 STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFED 3418
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+YWTDW+ V + NK++G + + T +T P IHVYHPYRQP N C NG C
Sbjct: 3419 TIYWTDWNTRTVEKGNKYDGSNRQ--TLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGC 3476
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLL 740
SHLCL P +C CP+ + L
Sbjct: 3477 SHLCL----IKPGGKGFTCECPDDFRTL 3500
Score = 470 bits (1159), Expect = e-132
Identities = 271/747 (36%), Positives = 372/747 (49%), Gaps = 52/747 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGL 78
SRTC +FRC GRCIP +WKCD + DC D SDE C ++ +C + F C ++
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP+ C+ DC D SDE CE C P +F C K C+PL W CD DC D S
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC--KNHHCIPLRWQCDGQNDCGDNS 3749
Query: 138 DEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
DE+ C C EF C N +CI RW+ E C TC P+ +F CT G
Sbjct: 3750 DEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPE-YFQCTSG 3808
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
C+ + CDG DC D SDE C + + C +T FEC + + C+ W
Sbjct: 3809 HCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHV-CIPPYWKCDGDDDC 3867
Query: 257 XXXXXEALELCRGNVTCRL-DQFQCKDHSCIPGALYCNGVKDCPDGSD--EYNCTRQKTI 313
E L LC +V C ++F+C ++ CI CNGV DC DG+D E +C +
Sbjct: 3868 GDGSDEELHLCL-DVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPK 3926
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG-ENECEKNNGGCSQRCVD-TP 371
E+ CG G CIP VCD DC ++ DE G E C +N C Q C
Sbjct: 3927 PCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI--CEQNCTQLNE 3984
Query: 372 IGYYCDCEKGYK--LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-ARDPRDR 428
G+ C C G++ + D +C DI+EC G+C Q C N KG+++C C G+ + R
Sbjct: 3985 GGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRPG 4044
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVF---RTGM-IFWSD 484
RC A P LL IRK +L + D + A+DY + G+ + +
Sbjct: 4045 KRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPKDIGLSVVYYT 4104
Query: 485 VNDE--------KIYKAPIDEG----TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
V E + Y + G Q + + ++ DG+AVDWV H+YW+D +
Sbjct: 4105 VRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNK 4164
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
IE++ L G RK LI L++P AIA+NP G MFWTDWG+ PKIE A M+G R+ +V
Sbjct: 4165 RIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKIESAWMNGEDRNILV 4224
Query: 593 SYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFE 651
D+ WP GL++D L R+YW D K + I + YDG+ RR+I + E + +P+S+ FE
Sbjct: 4225 FEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVI--AKEAM-NPYSLDIFE 4281
Query: 652 DWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVIHVYHPYRQPDGV-NHCAAVN 709
D +YW +K V++ NKF GK + + L + ++H R V N C +
Sbjct: 4282 DQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---VRIFHQLRYNKSVPNLCKQI- 4337
Query: 710 GHCSHLCLPAPRFGPNSPRVSCACPNG 736
CSHLCL P SCACP G
Sbjct: 4338 --CSHLCLLRP------GGYSCACPQG 4356
Score = 433 bits (1067), Expect = e-120
Identities = 240/704 (34%), Positives = 341/704 (48%), Gaps = 38/704 (5%)
Query: 61 ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGEC 120
A+ C F C S G CIP WRCD T DC D +DE C V C F C+ + G+C
Sbjct: 23 ASGQECDSAHFRCGS-GHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSE-GQC 80
Query: 121 VPLTWMCDDNPDCSDGSDEKA-CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEV 178
+P +W+CD + DC DGSDE+ C++ TC S + TC NG+CI + E
Sbjct: 81 IPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADEN 140
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECN 238
C PTC+ +C +G C + CD VDC D SDE+ C C+ EF C
Sbjct: 141 DCQYPTCE---QLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI------CLHNEFSCG 191
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ C+ RA+V E C TC QF C CI C+G DC
Sbjct: 192 NG-ECIPRAYVCDHDNDCQDGSDE--HACN-YPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 299 PDGSDEYNCT---RQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR---- 350
D DE C C R E+ C G CI + KVCD +DCP EDE
Sbjct: 248 KDNGDEDGCESGPHDVHKCSPR-EWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGSCSQICIN 408
C C N C +C +TP G C C GY + D+RTC + D+C G C Q C +
Sbjct: 307 CSMTLCSALN--CQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCES 364
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
G C C GY + + + G S++F+ D+ + +V
Sbjct: 365 RPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRG 424
Query: 469 TALDYVFRTGM--IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYW 526
A+ F + +FW+D K++ I+ G V+ + T + LAVDWV N +Y
Sbjct: 425 VAVGVAFHYHLQRVFWTDTVQNKVFSVDIN-GLNIQEVLNVSVETPENLAVDWVNNKIYL 483
Query: 527 TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV---PKIERAGM 583
+T N I++ +L G+ R LI + L PR IA++P G++F++DW + PK+ERA M
Sbjct: 484 VETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFM 543
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRH 643
DGS+R +V + WP G+TLD++ +RVYWVD++ + I + YDG R+ ++H ++ H
Sbjct: 544 DGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPH 603
Query: 644 PFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVN 703
PF ++ FE V++TDW K AV +ANKF + + P + VYH RQP N
Sbjct: 604 PFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASL--RPYGVTVYHSLRQPYATN 661
Query: 704 HCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C NG C +C+ + R + C C G +L D++ C+
Sbjct: 662 PCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI 705
Score = 252 bits (618), Expect = 3e-66
Identities = 199/669 (29%), Positives = 297/669 (44%), Gaps = 98/669 (14%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ + TC+SSEF+C +GRCIP W CD E DC D+SDE P C ++ C F+C
Sbjct: 2858 YCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDE-PASCGHSERTCLADEFKC-DG 2915
Query: 77 GLCIPRSWRCDATADCPDGSDE---HQCEVEACGPEEFTC---RGKPGECVPLTWMCDDN 130
G CIP W CD DC D SDE HQC+ + C EF C R C+P +W+CD +
Sbjct: 2916 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGD 2975
Query: 131 PDCSDGSDE--KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC+DG DE TC +EFTCG G CI + E C TCQ Q
Sbjct: 2976 VDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQ-Q 3034
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRA 247
+ F+C +G+CIS + CD D DC DGSDE + TP+ C EF+C D C+
Sbjct: 3035 NQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE--PTCPPHEFKC-DNGRCI--- 3088
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS---DE 304
E ++LC LD C D+S G G+ +C D S +
Sbjct: 3089 --------------EMMKLCN-----HLD--DCLDNSDEKGC----GINECHDPSISGCD 3123
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
+NCT D T F C C P K+ C + + EC + CS
Sbjct: 3124 HNCT------DTLTSFYCS---CRPGYKLMSDKRTCVDID----------ECTEMPFVCS 3164
Query: 365 QRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-- 421
Q+C + Y C C GY + D +TC + +P + + + + GY
Sbjct: 3165 QKCENVIGSYICKCAPGYLREPDGKTCRQ-NSNIEP----YLIFSNRYYLRNLTIDGYFY 3219
Query: 422 --ARDPRDRTRCKATEGHPSLLF---ARKHDIRKISLDHHEMVAIVNDTKSAT---ALDY 473
+ D + L+ ++ I ++ L+ I+N A A+D+
Sbjct: 3220 SLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDW 3279
Query: 474 VFRTGMIFWSDVNDEKIYKAPIDEGTQRTV----VIGEQLITSD---GLAVDWVYNHLYW 526
V R ++W D + ++ + ++ G +R + V D GLA+ Y +LYW
Sbjct: 3280 VSR--KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 527 TDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
D GH +I + G + ++I +LE P I ++ ++W D + IE + ++G
Sbjct: 3338 ADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWAD-AHLGYIEYSDLEG 3396
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHP 644
HR T+ YD P+ + + +YW D T+ N YDGS R+ ++++T P
Sbjct: 3397 HHRHTV--YDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTT---HRP 3451
Query: 645 FSITTFEDW 653
F I + +
Sbjct: 3452 FDIHVYHPY 3460
Score = 237 bits (580), Expect = 1e-61
Identities = 192/666 (28%), Positives = 292/666 (43%), Gaps = 70/666 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + C S+ FRC +G CIP W+CD KDCSD +DE C + CQ+ F+C S+G
Sbjct: 23 ASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAV--VTCQQGYFKCQSEG 78
Query: 78 LCIPRSWRCDATADCPDGSDEHQ-CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP SW CD DC DGSDE Q C C + TC G+C+P + CD DC DG
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSN--GQCIPSEYRCDHVRDCPDG 136
Query: 137 SDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
+DE C TC ++ TC NG C E+ C T C + FSC +
Sbjct: 137 ADENDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDEINC-TEICL-HNEFSCGN 192
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI + CD D DC DGSDE C + P C +F C C+++ WV
Sbjct: 193 GECIPRAYVCDHDNDCQDGSDEHAC-NYP----TCGGYQFTCPSG-RCIYQNWVCDGEDD 246
Query: 256 XXXXXXE-ALELCRGNV-TCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK- 311
E E +V C ++ C + CI C+G+ DCP DE N + K
Sbjct: 247 CKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 312 ---TICDK-RTEFDCG----GGMCIPLSKVCDKHVD---CPNFEDEPRDRCGENECEKNN 360
T+C ++ C GG C H D C F+D C+
Sbjct: 307 CSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDD----------CQ-IW 355
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG 420
G C Q+C P + C CE+GY L + C+ D G S I N + + H
Sbjct: 356 GICDQKCESRPGRHLCHCEEGYILERGQYCKANDSF---GEASIIFSNGRDLLIGDIHGR 412
Query: 421 YAR---DPRDRTRCKATEGHPSL--LFARKHDIRKI------SLDHHEMVAIVNDTKSAT 469
R + ++R H L +F K+ L+ E++ + +T
Sbjct: 413 SFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENL 472
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTD- 528
A+D+V I+ + +I +D G+ R +I E L G+AVD +L+++D
Sbjct: 473 AVDWV--NNKIYLVETKVNRIDMVNLD-GSYRVTLITENLGHPRGIAVDPTVGYLFFSDW 529
Query: 529 ---TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
+G +E + + G+ RK L++ +L P + L+ + ++W D + IE DG
Sbjct: 530 ESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVD-SRFDYIETVTYDG 588
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHP 644
R T+V P+ + L +V++ D KM + + + + ++ ++ LR P
Sbjct: 589 IQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQAS--LR-P 645
Query: 645 FSITTF 650
+ +T +
Sbjct: 646 YGVTVY 651
Score = 221 bits (541), Expect = 6e-57
Identities = 145/433 (33%), Positives = 193/433 (44%), Gaps = 31/433 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
L E+ C S+E++C RCIP SW+CD DC D+SDED + C + C+ +F C +
Sbjct: 3587 LLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCAS--RTCRPGQFRC-A 3643
Query: 76 DGLCIPRSWRCDATADCPDGSDE--HQCEVEA--CGP-EEFTCRGKPGECVPLTWMCDDN 130
+G CIP++W+CD DC D SDE +C A C EF+C+ C+P +C+
Sbjct: 3644 NGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTN-YRCIPKWAVCNGV 3702
Query: 131 PDCSDGSDEKACNE-TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC D SDE+ C E TC +F C N CI +RW E C C +
Sbjct: 3703 DDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPREC-TE 3761
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
S F C + QCI + W CD DC D SDE C ++R+ C F+C CVH
Sbjct: 3762 SEFRCVNQQCIPSRWICDHYNDCGDNSDERDC----EMRT-CHPEYFQCTSG-HCVHSEL 3815
Query: 249 VXXXXXXXXXXXXEALELCR--GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
EA R C+ F+CK+H CIP C+G DC DGSDE
Sbjct: 3816 KCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEEL 3875
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE---NECEKNNGGC 363
C+ F C CI +VC+ DC + DE + C + C + C
Sbjct: 3876 HLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKC 3935
Query: 364 SQ-RCVDTPIGYYC-DCEKGYKLIDNRTCEDIDE--CADPGSCSQICIN-EKGTFKCECH 418
C+ P C D + D C E CA+ C Q C +G F C C
Sbjct: 3936 GNGHCI--PHDNVCDDADDCGDWSDELGCNKGKERTCAE-NICEQNCTQLNEGGFICSCT 3992
Query: 419 TGYARDPRDRTRC 431
G+ + DRT C
Sbjct: 3993 AGFETNVFDRTSC 4005
Score = 218 bits (533), Expect = 5e-56
Identities = 186/670 (27%), Positives = 268/670 (40%), Gaps = 59/670 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV---CTATKMVCQEYRFECLSDGL 78
TC+ + F C GRC+ S++CD DC D SDE + C AT F C ++
Sbjct: 2740 TCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATT------EFMC-NNRR 2792
Query: 79 CIPRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIPR + C+ +C D SDE C C C C+P ++CD + DC D
Sbjct: 2793 CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKCHNS-NICIPRVYLCDGDNDCGDN 2851
Query: 137 SDEK---ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE-VKC--PTPTCQPQSH 190
SDE TC S EF C +G+CI W E C TC
Sbjct: 2852 SDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCL-ADE 2910
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-NDR---ITCVHR 246
F C G+CI + W CDGD DC D SDE C +EF C NDR C+ +
Sbjct: 2911 FKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQ--NQNCSDSEFLCVNDRPPDRRCIPQ 2968
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
+WV E R TC ++F C CIP C+ DC D SDE
Sbjct: 2969 SWVCDGDVDCTDGYDENQNCTRR--TCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERG 3026
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC--GENECEKNNGGCS 364
C Q C ++ +F C G CI + VCD+ DC + DE C E C + C
Sbjct: 3027 CLYQ--TC-QQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCD 3083
Query: 365 Q-RCVDTP--IGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFKCECHT 419
RC++ + DC D + C I+EC DP C C + +F C C
Sbjct: 3084 NGRCIEMMKLCNHLDDCLDN---SDEKGC-GINECHDPSISGCDHNCTDTLTSFYCSCRP 3139
Query: 420 GYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRT 477
GY + D+ C + + F + + A + + T
Sbjct: 3140 GY-KLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNSNIE 3198
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELS 537
+ +S N + ID G ++++ E L L D V LYW DT IE
Sbjct: 3199 PYLIFS--NRYYLRNLTID-GYFYSLIL-EGLDNVVALDFDRVEKRLYWIDTQRQVIERM 3254
Query: 538 DLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVK 597
L ++ +I RL ++A++ + ++W D ++ + + ++G HR + + V
Sbjct: 3255 FLNKTNKETIINHRLPAAESLAVDWVSRKLYWLD-ARLDGLFVSDLNGGHRRMLAQHCVD 3313
Query: 598 W--------PNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
P GL L +YW D I DG+ + +I+ + + +I
Sbjct: 3314 ANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITID 3373
Query: 649 TFEDWVYWTD 658
D +YW D
Sbjct: 3374 YTNDLLYWAD 3383
Score = 217 bits (531), Expect = 9e-56
Identities = 132/369 (35%), Positives = 170/369 (46%), Gaps = 30/369 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +S F C GRCI WKCDN+ DC D SDE +VC C F C ++G C+
Sbjct: 2700 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCAL--HTCSPTAFTC-ANGRCVQY 2756
Query: 83 SWRCDATADCPDGSDEHQCEVEAC-GPEEFTCRGKPGECVPLTWMCDDNPDCSDG--SDE 139
S+RCD DC DGSDE C C EF C + C+P ++C+ +C D SDE
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNR--RCIPREFICNGVDNCHDNNTSDE 2814
Query: 140 KAC-NETCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTD 195
K C + TC+S C N CI ++ E C T TC S F C
Sbjct: 2815 KNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEFQCAS 2873
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI W+CD + DC D SDE S C++ EF+C D C+ W+
Sbjct: 2874 GRCIPQHWYCDQETDCFDASDEP--ASCGHSERTCLADEFKC-DGGRCIPSEWICDGDND 2930
Query: 256 XXXXXXEALELCRGNVTCRLDQFQC-----KDHSCIPGALYCNGVKDCPDGSDE-YNCTR 309
E N C +F C D CIP + C+G DC DG DE NCTR
Sbjct: 2931 CGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTR 2990
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
+ C + EF CG G+CIP CD+H DC ++ DE C C++N C RC+
Sbjct: 2991 R--TCSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDE--RGCLYQTCQQNQFTCQNGRCI 3045
Query: 369 DTPIGYYCD 377
+ CD
Sbjct: 3046 SKT--FVCD 3052
Score = 211 bits (515), Expect = 8e-54
Identities = 136/388 (35%), Positives = 182/388 (46%), Gaps = 38/388 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMVCQEYRFECLSDG 77
+ TC+SS F C G CIP W+CD DC D SDE PT A+ C + ++ C +
Sbjct: 1064 NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPAS---CLDTQYTC-DNH 1119
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CI ++W CD DC DGSDE C E C P +F C C+ L+++CD + DC DG
Sbjct: 1120 QCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNH--RCIDLSFVCDGDKDCVDG 1177
Query: 137 SDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSHFSC 193
SDE C C + +F C +G KCI + E CPT P F C
Sbjct: 1178 SDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 194 -TDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
DG CI +W CDG DC GSDE CV PK C S+ F C D C+HRAW+
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHNACV--PKT---CPSSYFHC-DNGNCIHRAWLCD 1291
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C Q+QC H+ C+ ++ C+G+ DCP+G+DE
Sbjct: 1292 RDNDCGDMSDEK-DCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE------ 1344
Query: 311 KTICDKRTEFDCGGGM---CI--PLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCS 364
+C+ + D GG C+ P C + D C + +EC+ G CS
Sbjct: 1345 SPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDS--KTCEDIDECD-ILGSCS 1401
Query: 365 QRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
Q C + + C C+ GY L D RTC+
Sbjct: 1402 QHCYNMRGSFRCSCDTGYMLESDGRTCK 1429
Score = 198 bits (483), Expect = 6e-50
Identities = 115/365 (31%), Positives = 183/365 (50%), Gaps = 22/365 (6%)
Query: 396 CADP-GSCSQICI------NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI 448
C D G C Q+C+ N+ F+C+C G+ D +R C A + L+F+ + I
Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDER-HCIAVQNF--LIFSSQVAI 719
Query: 449 RKI----SLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVV 504
R I S MV + + +D+ + IF+SD++ I+K ID GT R ++
Sbjct: 720 RGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKID-GTGREIL 778
Query: 505 IGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLE 564
++ + LA DW+ +LYWTD+ + I + L R+ +++ L PR++ ++P
Sbjct: 779 AANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQ-YLNNPRSVVVHPFA 837
Query: 565 GWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
G++F+TDW + KI RA DGSH +++ + WPNGL +D R+YWVDA + I
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHS 897
Query: 625 NYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTL 684
+DG RR + H E + HPF + F + +++TDW A+ R K +G ++ I S
Sbjct: 898 TFDGLDRRRLGH-IEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIAY 956
Query: 685 QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQ 744
+ + + + N NG CSH C P P F RV C CP G++L +
Sbjct: 957 ILHLKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPNF----QRV-CGCPYGMRLASNHL 1011
Query: 745 MCVED 749
C D
Sbjct: 1012 TCEGD 1016
Score = 193 bits (470), Expect = 2e-48
Identities = 115/335 (34%), Positives = 155/335 (46%), Gaps = 28/335 (8%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C+S++F C +CIP+ WKCD +KDCSD SDE + + C+ +F+C SDG C
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE---LALCPQRFCRLGQFQC-SDGNCTS 3567
Query: 82 RSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
C+A +CPDGSDE + CE C E+ C K C+P +W CD DC D SDE
Sbjct: 3568 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANK--RCIPESWQCDTFNDCEDNSDE 3625
Query: 140 KA---CNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPT--CQPQSHFS 192
+ + TCR +F C NG+CI W E +C + C + FS
Sbjct: 3626 DSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 3685
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C T+ +CI W C+G DC D SDE GC + R+ +F C + C+ W
Sbjct: 3686 CKTNYRCIPKWAVCNGVDDCRDNSDEQGC----EERTCHPVGDFRCKNH-HCIPLRWQCD 3740
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK 311
E E C C +F+C + CIP C+ DC D SDE +C +
Sbjct: 3741 GQNDCGDNSDE--ENCAPR-ECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDC--EM 3795
Query: 312 TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
C F C G C+ CD DC + DE
Sbjct: 3796 RTCHPE-YFQCTSGHCVHSELKCDGSADCLDASDE 3829
Score = 180 bits (439), Expect = 1e-44
Identities = 111/359 (30%), Positives = 174/359 (48%), Gaps = 21/359 (5%)
Query: 400 GSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD--- 454
G CS +C G T KC+C G + D C A L+FA + +R + LD
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCAFGTLQS--DGKNC-AISTENFLIFALSNSLRSLHLDPEN 2407
Query: 455 HHEMVAIVNDTKSATALDYVFRTGMIFWSD---VNDEKIYKAPIDEGTQRTVVIGEQLIT 511
H +N ++ +LDY + I+++ +I A + G VI + T
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGT 2467
Query: 512 SDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
+DG+A DW+ +Y++D + I G+ R ++ R + +PRAI L+P +G+++W D
Sbjct: 2468 ADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIAR--VPKPRAIVLDPCQGYLYWAD 2525
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
W KIERA + G+ R IV+ + P+GLTLD +YWVDA + I G R
Sbjct: 2526 WDTHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQRIERSTLTGVDR 2585
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+I+++ H F +T + ++YWTD +YRANK++G A+T T+ L P I+
Sbjct: 2586 EVIVNAAV---HAFGLTLYGQYIYWTDLYTQRIYRANKYDGSGQIAMT-TNLLSQPRGIN 2641
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
++ N C NG CSH+C P GPN C L + + C+ D+
Sbjct: 2642 TVVKNQKQQCNNPCEQFNGGCSHICAP----GPNGAECQCPHEGNWYLANNRKHCIVDN 2696
Score = 171 bits (416), Expect = 8e-42
Identities = 108/318 (33%), Positives = 145/318 (45%), Gaps = 23/318 (7%)
Query: 65 VCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGECVPL 123
+C +F C ++ CIP W+CD DC DGSDE C C +F C G C
Sbjct: 3511 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQC--SDGNCTSP 3568
Query: 124 TWMCDDNPDCSDGSDEK--AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--V 178
+C+ + +C DGSDE C N C S+E+ C N +CI W E
Sbjct: 3569 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSS 3628
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCIS-TEF 235
C + TC+P F C +G+CI W CD D DC D SDE C+S+ + C + TEF
Sbjct: 3629 HCASRTCRP-GQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHL---CDNFTEF 3684
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C C+ + V E + C + F+CK+H CIP C+G
Sbjct: 3685 SCKTNYRCIPKWAVCNGVDDCRDNSDE--QGCEERTCHPVGDFRCKNHHCIPLRWQCDGQ 3742
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE 355
DC D SDE NC ++ C + +EF C CIP +CD + DC + DE RD C
Sbjct: 3743 NDCGDNSDEENCAPRE--CTE-SEFRCVNQQCIPSRWICDHYNDCGDNSDE-RD-CEMRT 3797
Query: 356 CEKNNGGC-SQRCVDTPI 372
C C S CV + +
Sbjct: 3798 CHPEYFQCTSGHCVHSEL 3815
Score = 156 bits (378), Expect = 3e-37
Identities = 118/409 (28%), Positives = 200/409 (48%), Gaps = 36/409 (8%)
Query: 380 KGYKLIDNRTC-EDIDECADP-GSCSQICINEKG-TFKCECHTGYARDPRDRTRCKATEG 436
+G ++ R E + C++ +C QIC+ G F C C TG+ +P +R+ C
Sbjct: 2005 RGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRS-CSPYNS 2063
Query: 437 HPSLLFARKHDIRKISL---DHHE-MVAIVNDTKSATALDYVFRTGMIFWSD-----VND 487
++ + IR SL DH E MV + ++A +D +G I+W D +D
Sbjct: 2064 F--IVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASD 2121
Query: 488 EKIYKAPIDEGTQRTVV---IGEQLITSDGLAVDWVYNHLYWTDT--GHNHIELSDLQGN 542
I + D + +V IGE + G+AVDWV +LY+T+ IE+ +
Sbjct: 2122 NAIRRIKPDGSSLMNIVTHGIGENGVR--GIAVDWVAGNLYFTNAFVSETLIEVLRINTT 2179
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGL 602
R++L++ ++ PR I ++P ++FW D+GQ PKIER+ +D ++R+ +VS + P GL
Sbjct: 2180 YRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGL 2239
Query: 603 TLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKT 662
+D VYWVD ++ I+ +G +I + + P+ IT FE+ + W D +
Sbjct: 2240 AVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSR-YPTPYGITVFENSIIWVDRNLK 2298
Query: 663 AVYRANKFNGKDVEAIT----STHTLQNPMVIHVYHPYRQPDGVNH--CAAVNGHCSHLC 716
+++A+K ++ E T + + L++ + R P VN+ C NG CSHLC
Sbjct: 2299 KIFQASK-EPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLC 2357
Query: 717 LPAPRFGPNSPRVSCACPNGLKLLPDDQMC-VEDSKYHFLPFYNNFRSI 764
P G ++P+ C C G L D + C + + N+ RS+
Sbjct: 2358 FALP--GLHTPK--CDCAFG-TLQSDGKNCAISTENFLIFALSNSLRSL 2401
Score = 146 bits (354), Expect = 3e-34
Identities = 81/207 (39%), Positives = 102/207 (49%), Gaps = 13/207 (6%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + TC S+F C RCI LS+ CD +KDC D SDE V + C +F+C S
Sbjct: 1144 NSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCV-----LNCTASQFKCASGD 1198
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVE---ACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
CI + RCD DC D SDE C C +EF C+ + G C+P W CD +PDC
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGICIPNFWECDGHPDCL 1257
Query: 135 DGSDE-KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHF 191
GSDE AC +TC S F C NG CI W+ E CPT P P +
Sbjct: 1258 YGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQW 1317
Query: 192 SCTDGQ-CISAWWHCDGDVDCADGSDE 217
C C++ CDG DC +G+DE
Sbjct: 1318 QCLGHNICVNLSVVCDGIFDCPNGTDE 1344
Score = 141 bits (342), Expect = 7e-33
Identities = 111/373 (29%), Positives = 175/373 (46%), Gaps = 34/373 (9%)
Query: 393 IDECADPGSCSQICI-NEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIR 449
++ CA CS +C+ + +G + C C +G++ P D C + P L+ R+H I
Sbjct: 1701 VNPCAF-SRCSHLCLLSSQGPHFYSCVCPSGWSLSP-DLLNC-LRDDQPFLITVRQHIIF 1757
Query: 450 KISLDHHEMV--AIVNDTKSATALDYVFRTG--MIFWSDVNDEKIYKAPIDEGTQRTVVI 505
ISL+ A+V LD F I+W + N +I++ D GT RTV
Sbjct: 1758 GISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-NPGEIHRVKTD-GTNRTVFA 1815
Query: 506 GEQLI-TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMR--KILIRDR-----LEEPRA 557
++ S LA+DW+ +LY T+ IE+ L G++R K LI + + P
Sbjct: 1816 SISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIG 1875
Query: 558 IALNPLEGWMFWTDWGQ---VP-KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
I ++P G ++W+D G VP KI A MDG+ T+ + +++ +TLD+ Q++YW
Sbjct: 1876 ITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQKLYW 1935
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
I N DG+ R +++H L HP+ I + ++Y+TD + R +K G
Sbjct: 1936 AVTGRGVIERGNVDGTDRMILVHQ---LSHPWGIAVHDSFLYYTDEQYEVIERVDKATG- 1991
Query: 674 DVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
I + N + VYH + N C+ C +CLP P SCAC
Sbjct: 1992 -ANKIVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVP-----GGLFSCAC 2045
Query: 734 PNGLKLLPDDQMC 746
G KL PD++ C
Sbjct: 2046 ATGFKLNPDNRSC 2058
Score = 131 bits (316), Expect = 1e-29
Identities = 88/276 (31%), Positives = 124/276 (44%), Gaps = 23/276 (8%)
Query: 144 ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQCISA 201
E C + FTC NG+CI W E++ C TC P + F+C +G+C+
Sbjct: 2698 ERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTA-FTCANGRCVQY 2756
Query: 202 WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXX 261
+ CD DC DGSDE GC+ R +TEF CN+R C+ R ++
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCL----FRDCNATTEFMCNNR-RCIPREFICNGVDNCHDNNT 2811
Query: 262 EALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
+ C TC+ +C + + CIP C+G DC D SDE N T T +EF
Sbjct: 2812 SDEKNCPDR-TCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDE-NPTYCTTHTCSSSEF 2869
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGC-SQRCVDTPIGYYCD 377
C G CIP CD+ DC + DEP CG +E C + C RC+ P + CD
Sbjct: 2870 QCASGRCIPQHWYCDQETDCFDASDEPAS-CGHSERTCLADEFKCDGGRCI--PSEWICD 2926
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQ---ICINEK 410
G + + ED +CS +C+N++
Sbjct: 2927 ---GDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDR 2959
Score = 124 bits (300), Expect = 9e-28
Identities = 76/249 (30%), Positives = 104/249 (41%), Gaps = 14/249 (5%)
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSH 190
C + E C F C NG+C+ ++ E C T TC S
Sbjct: 1013 CEGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCS-SSA 1071
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
F+C G+CI A W CD DC DGSDE C + + C+ T++ C D C+ + WV
Sbjct: 1072 FTCGHGECIPAHWRCDKRNDCVDGSDEHNCPT--HAPASCLDTQYTC-DNHQCISKNWVC 1128
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C TC+ QF C +H CI + C+G KDC DGSDE C
Sbjct: 1129 DTDNDCGDGSDE--KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLN 1186
Query: 311 KTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQRCV 368
T ++F C G CI ++ CD DC + DE C + C + +
Sbjct: 1187 CT----ASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGI 1242
Query: 369 DTPIGYYCD 377
P + CD
Sbjct: 1243 CIPNFWECD 1251
Score = 117 bits (282), Expect = 1e-25
Identities = 100/339 (29%), Positives = 136/339 (40%), Gaps = 31/339 (9%)
Query: 113 CRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXX 171
C KPG T C D+ S C C S +F C N KCI + W
Sbjct: 3480 CLIKPGG-KGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDC 3538
Query: 172 XXXXXEVK-CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPC 230
E+ CP C+ F C+DG C S C+ +C DGSDE + C
Sbjct: 3539 SDGSDELALCPQRFCR-LGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCE---NHHC 3594
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGAL 290
S E++C ++ C+ +W E C TCR QF+C + CIP A
Sbjct: 3595 DSNEWQCANK-RCIPESWQCDTFNDCEDNSDEDSSHCASR-TCRPGQFRCANGRCIPQAW 3652
Query: 291 YCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEP 347
C+ DC D SDE C +CD TEF C CIP VC+ DC + DE
Sbjct: 3653 KCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE- 3711
Query: 348 RDRCGENECEK-NNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQI 405
C E C + C + C+ P+ + CD + DN D + CA P C++
Sbjct: 3712 -QGCEERTCHPVGDFRCKNHHCI--PLRWQCDGQNDCG--DN---SDEENCA-PRECTES 3762
Query: 406 ---CINEK---GTFKCECHTGYARDPRDRTRCKATEGHP 438
C+N++ + C+ H D D C+ HP
Sbjct: 3763 EFRCVNQQCIPSRWICD-HYNDCGDNSDERDCEMRTCHP 3800
Score = 64.1 bits (149), Expect = 2e-09
Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY-CDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEK 410
N C N C Q C+ P G + C C G+KL DNR+C + S I + +
Sbjct: 2020 NGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLE 2079
Query: 411 GTFKCECHTGYARDPRDRTRCKATEGHPSLLF-------ARKHDIRKISLDHHEMVAIV- 462
+ E A R+ + + A + IR+I D ++ IV
Sbjct: 2080 LSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVT 2139
Query: 463 ----NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ A+D+V + F + E + + T R V++ + + VD
Sbjct: 2140 HGIGENGVRGIAVDWV-AGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVD 2198
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+L+W D G IE S L R +L+ + + PR +A++ +G+++W D +
Sbjct: 2199 PKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVD-DSLDI 2257
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTI 621
I R ++G + S ++ Y ++P + + + WVD + I
Sbjct: 2258 IARIRINGEN-SEVIRYGSRYPTPYGITVFENSIIWVDRNLKKI 2300
Score = 39.9 bits (89), Expect = 0.033
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDC--EKGYKLIDNRTCEDIDECADPGSCSQI 405
+ +C N CE+ NGGCS C P G C C E + L +NR +D G+ S
Sbjct: 2648 KQQCN-NPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFT 2706
Query: 406 CIN 408
C N
Sbjct: 2707 CSN 2709
Score = 34.3 bits (75), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY---CDCEKGYKLIDNRTC 390
N C +NNGGCS C P G + CDC G D + C
Sbjct: 2344 NPCLENNGGCSHLCFALP-GLHTPKCDCAFGTLQSDGKNC 2382
>AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 539 bits (1330), Expect = e-152
Identities = 290/742 (39%), Positives = 388/742 (52%), Gaps = 35/742 (4%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C F CK GRC+P + CD DC D+SDE +C C F C G CIP
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQ--LCGTLNNTCSSSAFTC-GHGECIPA 1082
Query: 83 SWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
WRCD DC DGSDEH C A C ++TC +C+ W+CD + DC DGSDE
Sbjct: 1083 HWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNH--QCISKNWVCDTDNDCGDGSDE 1140
Query: 140 KACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG- 196
K CN ETC+ +F C N +CI + +V EV C C S F C G
Sbjct: 1141 KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVL-NCTA-SQFKCASGD 1198
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+CI CDG DC+D SDE GC + P C S EF+C + C+ W
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPP--GMCHSDEFQCQEDGICIPNFWECDGHPDC 1256
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E C TC F C + +CI A C+ DC D SDE +C Q C
Sbjct: 1257 LYGSDEH-NACVPK-TCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPS 1314
Query: 317 RTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
++ C G +C+ LS VCD DCPN DE C N C NGGC+ CV P G
Sbjct: 1315 -WQWQCLGHNICVNLSVVCDGIFDCPNGTDES-PLCNGNSCSDFNGGCTHECVQEPFGAK 1372
Query: 376 CDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
C C G+ L D++TCEDIDEC GSCSQ C N +G+F+C C TGY + RT CK T
Sbjct: 1373 CLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRT-CKVT 1431
Query: 435 EGHPSLLFARKHD---IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIY 491
LL + ++ H + ++V + A+D+ +G IFWSD K +
Sbjct: 1432 ASESLLLLVASQNKIIADSVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTW 1491
Query: 492 KAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDR 551
A GT R VV +I ++ +A+DWV +LYWTD IE+S + G+ R +LI
Sbjct: 1492 SA-FQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKN 1550
Query: 552 LEEPRAIALNPL--EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQ 609
L PR +AL+P E +FW+DWG P+IERA MDGS R+ IV + WP GLT+D +
Sbjct: 1551 LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNR 1610
Query: 610 RVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANK 669
+Y++D+ ++ + C+Y+G RR ++ S ++RHP+++T FED VYWTD V RANK
Sbjct: 1611 LLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANK 1670
Query: 670 FNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRV 729
++G + + + +Q P+ I HP +QP+ VN CA CSHLCL + + GP+
Sbjct: 1671 WHGGNQSVV--MYNIQWPLGIVAVHPSKQPNSVNPCAF--SRCSHLCLLSSQ-GPHF--Y 1723
Query: 730 SCACPNGLKLLPDDQMCVEDSK 751
SC CP+G L PD C+ D +
Sbjct: 1724 SCVCPSGWSLSPDLLNCLRDDQ 1745
Score = 485 bits (1196), Expect = e-136
Identities = 266/748 (35%), Positives = 374/748 (50%), Gaps = 53/748 (7%)
Query: 21 RTCTSS-EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R C ++ EF C RCIP + C+ +C D++ D C CQ +C + +C
Sbjct: 2778 RDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCP--DRTCQSGYTKCHNSNIC 2835
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
IPR + CD DC D SDE+ C C EF C G C+P W CD DC D S
Sbjct: 2836 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS--GRCIPQHWYCDQETDCFDAS 2893
Query: 138 DEKA-CNE---TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK---CPTPTCQPQSH 190
DE A C TC +DEF C G+CI W+ E K C C S
Sbjct: 2894 DEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS-DSE 2952
Query: 191 FSCT-----DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D +CI W CDGDVDC DG DE + R C EF C + C+
Sbjct: 2953 FLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDE----NQNCTRRTCSENEFTCGYGL-CIP 3007
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE- 304
+ + E L + TC+ +QF C++ CI C+ DC DGSDE
Sbjct: 3008 KIFRCDRHNDCGDYSDERGCLYQ---TCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDEL 3064
Query: 305 -YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGG 362
+ C + C EF C G CI + K+C+ DC + DE CG NEC + + G
Sbjct: 3065 MHLCHTPEPTCPPH-EFKCDNGRCIEMMKLCNHLDDCLDNSDEKG--CGINECHDPSISG 3121
Query: 363 CSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTG 420
C C DT +YC C GYKL+ D RTC DIDEC + P CSQ C N G++ C+C G
Sbjct: 3122 CDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPG 3181
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMI 480
Y R+P +T + + P L+F+ ++ +R +++D + I+ + ALD+ +
Sbjct: 3182 YLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRL 3241
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
+W D + I + +++ T + +I +L ++ LAVDWV LYW D + + +SDL
Sbjct: 3242 YWIDTQRQVIERMFLNK-TNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLN 3300
Query: 541 GNMRKILIRDRLE--------EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
G R++L + ++ PR +AL+P G+++W DWG I R GMDG+++S I+
Sbjct: 3301 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVII 3360
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S ++WPNG+T+D +YW DA + I + +G R + L HPF+IT FED
Sbjct: 3361 STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFED 3418
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+YWTDW+ V + NK++G + + T +T P IHVYHPYRQP N C NG C
Sbjct: 3419 TIYWTDWNTRTVEKGNKYDGSNRQ--TLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGC 3476
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLL 740
SHLCL P +C CP+ + L
Sbjct: 3477 SHLCL----IKPGGKGFTCECPDDFRTL 3500
Score = 469 bits (1157), Expect = e-131
Identities = 270/747 (36%), Positives = 372/747 (49%), Gaps = 52/747 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGL 78
SRTC +FRC GRCIP +WKCD + DC D SDE C ++ +C + F C ++
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP+ C+ DC D SDE CE C P +F C K C+PL W CD DC D S
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC--KNHHCIPLRWQCDGQNDCGDNS 3749
Query: 138 DEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
DE+ C C EF C N +CI RW+ E C TC P+ +F CT G
Sbjct: 3750 DEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPE-YFQCTSG 3808
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
C+ + CDG DC D SDE C + + C +T FEC + + C+ W
Sbjct: 3809 HCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHV-CIPPYWKCDGDDDC 3867
Query: 257 XXXXXEALELCRGNVTCRL-DQFQCKDHSCIPGALYCNGVKDCPDGSD--EYNCTRQKTI 313
E L LC +V C ++F+C ++ CI CNGV DC DG+D E +C +
Sbjct: 3868 GDGSDEELHLCL-DVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPK 3926
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG-ENECEKNNGGCSQRCVD-TP 371
E+ CG G CIP VCD DC ++ DE G E C +N C Q C
Sbjct: 3927 PCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI--CEQNCTQLNE 3984
Query: 372 IGYYCDCEKGYK--LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-ARDPRDR 428
G+ C C G++ + D +C DI+EC G+C Q C N KG+++C C G+ + R
Sbjct: 3985 GGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRPG 4044
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVF---RTGM-IFWSD 484
RC A P LL IRK +L + D + A+DY + G+ + +
Sbjct: 4045 KRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPEDIGLSVVYYT 4104
Query: 485 VNDE--------KIYKAPIDEG----TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
V E + Y + G Q + + ++ DG+AVDWV H+YW+D +
Sbjct: 4105 VRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNK 4164
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
IE++ L G RK LI L++P AIA+NP G MFWTDWG+ PK+E A M+G R+ +V
Sbjct: 4165 RIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNGEDRNILV 4224
Query: 593 SYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFE 651
D+ WP GL++D L R+YW D K + I + YDG+ RR+I + E + +P+S+ FE
Sbjct: 4225 FEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVI--AKEAM-NPYSLDIFE 4281
Query: 652 DWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVIHVYHPYRQPDGV-NHCAAVN 709
D +YW +K V++ NKF GK + + L + ++H R V N C +
Sbjct: 4282 DQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---VRIFHQLRYNKSVPNLCKQI- 4337
Query: 710 GHCSHLCLPAPRFGPNSPRVSCACPNG 736
CSHLCL P SCACP G
Sbjct: 4338 --CSHLCLLRP------GGYSCACPQG 4356
Score = 433 bits (1067), Expect = e-120
Identities = 240/704 (34%), Positives = 341/704 (48%), Gaps = 38/704 (5%)
Query: 61 ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGEC 120
A+ C F C S G CIP WRCD T DC D +DE C V C F C+ + G+C
Sbjct: 23 ASGQECDSAHFRCGS-GHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSE-GQC 80
Query: 121 VPLTWMCDDNPDCSDGSDEKA-CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEV 178
+P +W+CD + DC DGSDE+ C++ TC S + TC NG+CI + E
Sbjct: 81 IPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADEN 140
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECN 238
C PTC+ +C +G C + CD VDC D SDE+ C C+ EF C
Sbjct: 141 DCQYPTCE---QLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI------CLHNEFSCG 191
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ C+ RA+V E C TC QF C CI C+G DC
Sbjct: 192 NG-ECIPRAYVCDHDNDCQDGSDE--HACN-YPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 299 PDGSDEYNCT---RQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR---- 350
D DE C C R E+ C G CI + KVCD +DCP EDE
Sbjct: 248 KDNGDEDGCESGPHDVHKCSPR-EWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGSCSQICIN 408
C C N C +C +TP G C C GY + D+RTC + D+C G C Q C +
Sbjct: 307 CSMTLCSALN--CQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCES 364
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
G C C GY + + + G S++F+ D+ + +V
Sbjct: 365 RPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRG 424
Query: 469 TALDYVFRTGM--IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYW 526
A+ F + +FW+D K++ I+ G V+ + T + LAVDWV N +Y
Sbjct: 425 VAVGVAFHYHLQRVFWTDTVQNKVFSVDIN-GLNIQEVLNVSVETPENLAVDWVNNKIYL 483
Query: 527 TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV---PKIERAGM 583
+T N I++ +L G+ R LI + L PR IA++P G++F++DW + PK+ERA M
Sbjct: 484 VETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFM 543
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRH 643
DGS+R +V + WP G+TLD++ +RVYWVD++ + I + YDG R+ ++H ++ H
Sbjct: 544 DGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPH 603
Query: 644 PFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVN 703
PF ++ FE V++TDW K AV +ANKF + + P + VYH RQP N
Sbjct: 604 PFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASL--RPYGVTVYHSLRQPYATN 661
Query: 704 HCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C NG C +C+ + R + C C G +L D++ C+
Sbjct: 662 PCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI 705
Score = 252 bits (618), Expect = 3e-66
Identities = 199/669 (29%), Positives = 297/669 (44%), Gaps = 98/669 (14%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ + TC+SSEF+C +GRCIP W CD E DC D+SDE P C ++ C F+C
Sbjct: 2858 YCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDE-PASCGHSERTCLADEFKC-DG 2915
Query: 77 GLCIPRSWRCDATADCPDGSDE---HQCEVEACGPEEFTC---RGKPGECVPLTWMCDDN 130
G CIP W CD DC D SDE HQC+ + C EF C R C+P +W+CD +
Sbjct: 2916 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGD 2975
Query: 131 PDCSDGSDE--KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC+DG DE TC +EFTCG G CI + E C TCQ Q
Sbjct: 2976 VDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQ-Q 3034
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRA 247
+ F+C +G+CIS + CD D DC DGSDE + TP+ C EF+C D C+
Sbjct: 3035 NQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE--PTCPPHEFKC-DNGRCI--- 3088
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS---DE 304
E ++LC LD C D+S G G+ +C D S +
Sbjct: 3089 --------------EMMKLCN-----HLD--DCLDNSDEKGC----GINECHDPSISGCD 3123
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
+NCT D T F C C P K+ C + + EC + CS
Sbjct: 3124 HNCT------DTLTSFYCS---CRPGYKLMSDKRTCVDID----------ECTEMPFVCS 3164
Query: 365 QRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-- 421
Q+C + Y C C GY + D +TC + +P + + + + GY
Sbjct: 3165 QKCENVIGSYICKCAPGYLREPDGKTCRQ-NSNIEP----YLIFSNRYYLRNLTIDGYFY 3219
Query: 422 --ARDPRDRTRCKATEGHPSLLF---ARKHDIRKISLDHHEMVAIVNDTKSAT---ALDY 473
+ D + L+ ++ I ++ L+ I+N A A+D+
Sbjct: 3220 SLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDW 3279
Query: 474 VFRTGMIFWSDVNDEKIYKAPIDEGTQRTV----VIGEQLITSD---GLAVDWVYNHLYW 526
V R ++W D + ++ + ++ G +R + V D GLA+ Y +LYW
Sbjct: 3280 VSR--KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 527 TDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
D GH +I + G + ++I +LE P I ++ ++W D + IE + ++G
Sbjct: 3338 ADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWAD-AHLGYIEYSDLEG 3396
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHP 644
HR T+ YD P+ + + +YW D T+ N YDGS R+ ++++T P
Sbjct: 3397 HHRHTV--YDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTT---HRP 3451
Query: 645 FSITTFEDW 653
F I + +
Sbjct: 3452 FDIHVYHPY 3460
Score = 237 bits (580), Expect = 1e-61
Identities = 192/666 (28%), Positives = 292/666 (43%), Gaps = 70/666 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + C S+ FRC +G CIP W+CD KDCSD +DE C + CQ+ F+C S+G
Sbjct: 23 ASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAV--VTCQQGYFKCQSEG 78
Query: 78 LCIPRSWRCDATADCPDGSDEHQ-CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP SW CD DC DGSDE Q C C + TC G+C+P + CD DC DG
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSN--GQCIPSEYRCDHVRDCPDG 136
Query: 137 SDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
+DE C TC ++ TC NG C E+ C T C + FSC +
Sbjct: 137 ADENDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDEINC-TEICL-HNEFSCGN 192
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI + CD D DC DGSDE C + P C +F C C+++ WV
Sbjct: 193 GECIPRAYVCDHDNDCQDGSDEHAC-NYP----TCGGYQFTCPSG-RCIYQNWVCDGEDD 246
Query: 256 XXXXXXE-ALELCRGNV-TCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK- 311
E E +V C ++ C + CI C+G+ DCP DE N + K
Sbjct: 247 CKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 312 ---TICDK-RTEFDCG----GGMCIPLSKVCDKHVD---CPNFEDEPRDRCGENECEKNN 360
T+C ++ C GG C H D C F+D C+
Sbjct: 307 CSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDD----------CQ-IW 355
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG 420
G C Q+C P + C CE+GY L + C+ D G S I N + + H
Sbjct: 356 GICDQKCESRPGRHLCHCEEGYILERGQYCKANDSF---GEASIIFSNGRDLLIGDIHGR 412
Query: 421 YAR---DPRDRTRCKATEGHPSL--LFARKHDIRKI------SLDHHEMVAIVNDTKSAT 469
R + ++R H L +F K+ L+ E++ + +T
Sbjct: 413 SFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENL 472
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTD- 528
A+D+V I+ + +I +D G+ R +I E L G+AVD +L+++D
Sbjct: 473 AVDWV--NNKIYLVETKVNRIDMVNLD-GSYRVTLITENLGHPRGIAVDPTVGYLFFSDW 529
Query: 529 ---TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
+G +E + + G+ RK L++ +L P + L+ + ++W D + IE DG
Sbjct: 530 ESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVD-SRFDYIETVTYDG 588
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHP 644
R T+V P+ + L +V++ D KM + + + + ++ ++ LR P
Sbjct: 589 IQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQAS--LR-P 645
Query: 645 FSITTF 650
+ +T +
Sbjct: 646 YGVTVY 651
Score = 221 bits (541), Expect = 6e-57
Identities = 145/433 (33%), Positives = 193/433 (44%), Gaps = 31/433 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
L E+ C S+E++C RCIP SW+CD DC D+SDED + C + C+ +F C +
Sbjct: 3587 LLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCAS--RTCRPGQFRC-A 3643
Query: 76 DGLCIPRSWRCDATADCPDGSDE--HQCEVEA--CGP-EEFTCRGKPGECVPLTWMCDDN 130
+G CIP++W+CD DC D SDE +C A C EF+C+ C+P +C+
Sbjct: 3644 NGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTN-YRCIPKWAVCNGV 3702
Query: 131 PDCSDGSDEKACNE-TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC D SDE+ C E TC +F C N CI +RW E C C +
Sbjct: 3703 DDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPREC-TE 3761
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
S F C + QCI + W CD DC D SDE C ++R+ C F+C CVH
Sbjct: 3762 SEFRCVNQQCIPSRWICDHYNDCGDNSDERDC----EMRT-CHPEYFQCTSG-HCVHSEL 3815
Query: 249 VXXXXXXXXXXXXEALELCR--GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
EA R C+ F+CK+H CIP C+G DC DGSDE
Sbjct: 3816 KCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEEL 3875
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE---NECEKNNGGC 363
C+ F C CI +VC+ DC + DE + C + C + C
Sbjct: 3876 HLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKC 3935
Query: 364 SQ-RCVDTPIGYYC-DCEKGYKLIDNRTCEDIDE--CADPGSCSQICIN-EKGTFKCECH 418
C+ P C D + D C E CA+ C Q C +G F C C
Sbjct: 3936 GNGHCI--PHDNVCDDADDCGDWSDELGCNKGKERTCAE-NICEQNCTQLNEGGFICSCT 3992
Query: 419 TGYARDPRDRTRC 431
G+ + DRT C
Sbjct: 3993 AGFETNVFDRTSC 4005
Score = 218 bits (533), Expect = 5e-56
Identities = 186/670 (27%), Positives = 268/670 (40%), Gaps = 59/670 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV---CTATKMVCQEYRFECLSDGL 78
TC+ + F C GRC+ S++CD DC D SDE + C AT F C ++
Sbjct: 2740 TCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATT------EFMC-NNRR 2792
Query: 79 CIPRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIPR + C+ +C D SDE C C C C+P ++CD + DC D
Sbjct: 2793 CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKCHNS-NICIPRVYLCDGDNDCGDN 2851
Query: 137 SDEK---ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE-VKC--PTPTCQPQSH 190
SDE TC S EF C +G+CI W E C TC
Sbjct: 2852 SDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCL-ADE 2910
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-NDR---ITCVHR 246
F C G+CI + W CDGD DC D SDE C +EF C NDR C+ +
Sbjct: 2911 FKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQ--NQNCSDSEFLCVNDRPPDRRCIPQ 2968
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
+WV E R TC ++F C CIP C+ DC D SDE
Sbjct: 2969 SWVCDGDVDCTDGYDENQNCTRR--TCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERG 3026
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC--GENECEKNNGGCS 364
C Q C ++ +F C G CI + VCD+ DC + DE C E C + C
Sbjct: 3027 CLYQ--TC-QQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCD 3083
Query: 365 Q-RCVDTP--IGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFKCECHT 419
RC++ + DC D + C I+EC DP C C + +F C C
Sbjct: 3084 NGRCIEMMKLCNHLDDCLDN---SDEKGC-GINECHDPSISGCDHNCTDTLTSFYCSCRP 3139
Query: 420 GYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRT 477
GY + D+ C + + F + + A + + T
Sbjct: 3140 GY-KLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNSNIE 3198
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELS 537
+ +S N + ID G ++++ E L L D V LYW DT IE
Sbjct: 3199 PYLIFS--NRYYLRNLTID-GYFYSLIL-EGLDNVVALDFDRVEKRLYWIDTQRQVIERM 3254
Query: 538 DLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVK 597
L ++ +I RL ++A++ + ++W D ++ + + ++G HR + + V
Sbjct: 3255 FLNKTNKETIINHRLPAAESLAVDWVSRKLYWLD-ARLDGLFVSDLNGGHRRMLAQHCVD 3313
Query: 598 W--------PNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
P GL L +YW D I DG+ + +I+ + + +I
Sbjct: 3314 ANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITID 3373
Query: 649 TFEDWVYWTD 658
D +YW D
Sbjct: 3374 YTNDLLYWAD 3383
Score = 217 bits (531), Expect = 9e-56
Identities = 132/369 (35%), Positives = 170/369 (46%), Gaps = 30/369 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +S F C GRCI WKCDN+ DC D SDE +VC C F C ++G C+
Sbjct: 2700 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCAL--HTCSPTAFTC-ANGRCVQY 2756
Query: 83 SWRCDATADCPDGSDEHQCEVEAC-GPEEFTCRGKPGECVPLTWMCDDNPDCSDG--SDE 139
S+RCD DC DGSDE C C EF C + C+P ++C+ +C D SDE
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNR--RCIPREFICNGVDNCHDNNTSDE 2814
Query: 140 KAC-NETCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTD 195
K C + TC+S C N CI ++ E C T TC S F C
Sbjct: 2815 KNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEFQCAS 2873
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI W+CD + DC D SDE S C++ EF+C D C+ W+
Sbjct: 2874 GRCIPQHWYCDQETDCFDASDEP--ASCGHSERTCLADEFKC-DGGRCIPSEWICDGDND 2930
Query: 256 XXXXXXEALELCRGNVTCRLDQFQC-----KDHSCIPGALYCNGVKDCPDGSDE-YNCTR 309
E N C +F C D CIP + C+G DC DG DE NCTR
Sbjct: 2931 CGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTR 2990
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
+ C + EF CG G+CIP CD+H DC ++ DE C C++N C RC+
Sbjct: 2991 R--TCSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDE--RGCLYQTCQQNQFTCQNGRCI 3045
Query: 369 DTPIGYYCD 377
+ CD
Sbjct: 3046 SKT--FVCD 3052
Score = 211 bits (515), Expect = 8e-54
Identities = 136/388 (35%), Positives = 182/388 (46%), Gaps = 38/388 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMVCQEYRFECLSDG 77
+ TC+SS F C G CIP W+CD DC D SDE PT A+ C + ++ C +
Sbjct: 1064 NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPAS---CLDTQYTC-DNH 1119
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CI ++W CD DC DGSDE C E C P +F C C+ L+++CD + DC DG
Sbjct: 1120 QCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNH--RCIDLSFVCDGDKDCVDG 1177
Query: 137 SDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSHFSC 193
SDE C C + +F C +G KCI + E CPT P F C
Sbjct: 1178 SDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 194 -TDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
DG CI +W CDG DC GSDE CV PK C S+ F C D C+HRAW+
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHNACV--PKT---CPSSYFHC-DNGNCIHRAWLCD 1291
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C Q+QC H+ C+ ++ C+G+ DCP+G+DE
Sbjct: 1292 RDNDCGDMSDEK-DCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE------ 1344
Query: 311 KTICDKRTEFDCGGGM---CI--PLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCS 364
+C+ + D GG C+ P C + D C + +EC+ G CS
Sbjct: 1345 SPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDS--KTCEDIDECD-ILGSCS 1401
Query: 365 QRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
Q C + + C C+ GY L D RTC+
Sbjct: 1402 QHCYNMRGSFRCSCDTGYMLESDGRTCK 1429
Score = 198 bits (483), Expect = 6e-50
Identities = 115/365 (31%), Positives = 183/365 (50%), Gaps = 22/365 (6%)
Query: 396 CADP-GSCSQICI------NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI 448
C D G C Q+C+ N+ F+C+C G+ D +R C A + L+F+ + I
Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDER-HCIAVQNF--LIFSSQVAI 719
Query: 449 RKI----SLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVV 504
R I S MV + + +D+ + IF+SD++ I+K ID GT R ++
Sbjct: 720 RGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKID-GTGREIL 778
Query: 505 IGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLE 564
++ + LA DW+ +LYWTD+ + I + L R+ +++ L PR++ ++P
Sbjct: 779 AANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQ-YLNNPRSVVVHPFA 837
Query: 565 GWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
G++F+TDW + KI RA DGSH +++ + WPNGL +D R+YWVDA + I
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHS 897
Query: 625 NYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTL 684
+DG RR + H E + HPF + F + +++TDW A+ R K +G ++ I S
Sbjct: 898 TFDGLDRRRLGH-IEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIAY 956
Query: 685 QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQ 744
+ + + + N NG CSH C P P F RV C CP G++L +
Sbjct: 957 ILHLKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPNF----QRV-CGCPYGMRLASNHL 1011
Query: 745 MCVED 749
C D
Sbjct: 1012 TCEGD 1016
Score = 193 bits (470), Expect = 2e-48
Identities = 115/335 (34%), Positives = 155/335 (46%), Gaps = 28/335 (8%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C+S++F C +CIP+ WKCD +KDCSD SDE + + C+ +F+C SDG C
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE---LALCPQRFCRLGQFQC-SDGNCTS 3567
Query: 82 RSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
C+A +CPDGSDE + CE C E+ C K C+P +W CD DC D SDE
Sbjct: 3568 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANK--RCIPESWQCDTFNDCEDNSDE 3625
Query: 140 KA---CNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPT--CQPQSHFS 192
+ + TCR +F C NG+CI W E +C + C + FS
Sbjct: 3626 DSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 3685
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C T+ +CI W C+G DC D SDE GC + R+ +F C + C+ W
Sbjct: 3686 CKTNYRCIPKWAVCNGVDDCRDNSDEQGC----EERTCHPVGDFRCKNH-HCIPLRWQCD 3740
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK 311
E E C C +F+C + CIP C+ DC D SDE +C +
Sbjct: 3741 GQNDCGDNSDE--ENCAPR-ECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDC--EM 3795
Query: 312 TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
C F C G C+ CD DC + DE
Sbjct: 3796 RTCHPE-YFQCTSGHCVHSELKCDGSADCLDASDE 3829
Score = 180 bits (439), Expect = 1e-44
Identities = 111/359 (30%), Positives = 174/359 (48%), Gaps = 21/359 (5%)
Query: 400 GSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD--- 454
G CS +C G T KC+C G + D C A L+FA + +R + LD
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCAFGTLQS--DGKNC-AISTENFLIFALSNSLRSLHLDPEN 2407
Query: 455 HHEMVAIVNDTKSATALDYVFRTGMIFWSD---VNDEKIYKAPIDEGTQRTVVIGEQLIT 511
H +N ++ +LDY + I+++ +I A + G VI + T
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGT 2467
Query: 512 SDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
+DG+A DW+ +Y++D + I G+ R ++ R + +PRAI L+P +G+++W D
Sbjct: 2468 ADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIAR--VPKPRAIVLDPCQGYLYWAD 2525
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
W KIERA + G+ R IV+ + P+GLTLD +YWVDA + I G R
Sbjct: 2526 WDTHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQRIERSTLTGVDR 2585
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+I+++ H F +T + ++YWTD +YRANK++G A+T T+ L P I+
Sbjct: 2586 EVIVNAAV---HAFGLTLYGQYIYWTDLYTQRIYRANKYDGSGQIAMT-TNLLSQPRGIN 2641
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
++ N C NG CSH+C P GPN C L + + C+ D+
Sbjct: 2642 TVVKNQKQQCNNPCEQFNGGCSHICAP----GPNGAECQCPHEGNWYLANNRKHCIVDN 2696
Score = 171 bits (416), Expect = 8e-42
Identities = 108/318 (33%), Positives = 145/318 (45%), Gaps = 23/318 (7%)
Query: 65 VCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGECVPL 123
+C +F C ++ CIP W+CD DC DGSDE C C +F C G C
Sbjct: 3511 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQC--SDGNCTSP 3568
Query: 124 TWMCDDNPDCSDGSDEK--AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--V 178
+C+ + +C DGSDE C N C S+E+ C N +CI W E
Sbjct: 3569 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSS 3628
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCIS-TEF 235
C + TC+P F C +G+CI W CD D DC D SDE C+S+ + C + TEF
Sbjct: 3629 HCASRTCRP-GQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHL---CDNFTEF 3684
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C C+ + V E + C + F+CK+H CIP C+G
Sbjct: 3685 SCKTNYRCIPKWAVCNGVDDCRDNSDE--QGCEERTCHPVGDFRCKNHHCIPLRWQCDGQ 3742
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE 355
DC D SDE NC ++ C + +EF C CIP +CD + DC + DE RD C
Sbjct: 3743 NDCGDNSDEENCAPRE--CTE-SEFRCVNQQCIPSRWICDHYNDCGDNSDE-RD-CEMRT 3797
Query: 356 CEKNNGGC-SQRCVDTPI 372
C C S CV + +
Sbjct: 3798 CHPEYFQCTSGHCVHSEL 3815
Score = 156 bits (378), Expect = 3e-37
Identities = 118/409 (28%), Positives = 200/409 (48%), Gaps = 36/409 (8%)
Query: 380 KGYKLIDNRTC-EDIDECADP-GSCSQICINEKG-TFKCECHTGYARDPRDRTRCKATEG 436
+G ++ R E + C++ +C QIC+ G F C C TG+ +P +R+ C
Sbjct: 2005 RGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRS-CSPYNS 2063
Query: 437 HPSLLFARKHDIRKISL---DHHE-MVAIVNDTKSATALDYVFRTGMIFWSD-----VND 487
++ + IR SL DH E MV + ++A +D +G I+W D +D
Sbjct: 2064 F--IVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASD 2121
Query: 488 EKIYKAPIDEGTQRTVV---IGEQLITSDGLAVDWVYNHLYWTDT--GHNHIELSDLQGN 542
I + D + +V IGE + G+AVDWV +LY+T+ IE+ +
Sbjct: 2122 NAIRRIKPDGSSLMNIVTHGIGENGVR--GIAVDWVAGNLYFTNAFVSETLIEVLRINTT 2179
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGL 602
R++L++ ++ PR I ++P ++FW D+GQ PKIER+ +D ++R+ +VS + P GL
Sbjct: 2180 YRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGL 2239
Query: 603 TLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKT 662
+D VYWVD ++ I+ +G +I + + P+ IT FE+ + W D +
Sbjct: 2240 AVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSR-YPTPYGITVFENSIIWVDRNLK 2298
Query: 663 AVYRANKFNGKDVEAIT----STHTLQNPMVIHVYHPYRQPDGVNH--CAAVNGHCSHLC 716
+++A+K ++ E T + + L++ + R P VN+ C NG CSHLC
Sbjct: 2299 KIFQASK-EPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLC 2357
Query: 717 LPAPRFGPNSPRVSCACPNGLKLLPDDQMC-VEDSKYHFLPFYNNFRSI 764
P G ++P+ C C G L D + C + + N+ RS+
Sbjct: 2358 FALP--GLHTPK--CDCAFG-TLQSDGKNCAISTENFLIFALSNSLRSL 2401
Score = 146 bits (354), Expect = 3e-34
Identities = 81/207 (39%), Positives = 102/207 (49%), Gaps = 13/207 (6%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + TC S+F C RCI LS+ CD +KDC D SDE V + C +F+C S
Sbjct: 1144 NSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCV-----LNCTASQFKCASGD 1198
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVE---ACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
CI + RCD DC D SDE C C +EF C+ + G C+P W CD +PDC
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGICIPNFWECDGHPDCL 1257
Query: 135 DGSDE-KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHF 191
GSDE AC +TC S F C NG CI W+ E CPT P P +
Sbjct: 1258 YGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQW 1317
Query: 192 SCTDGQ-CISAWWHCDGDVDCADGSDE 217
C C++ CDG DC +G+DE
Sbjct: 1318 QCLGHNICVNLSVVCDGIFDCPNGTDE 1344
Score = 141 bits (342), Expect = 7e-33
Identities = 111/373 (29%), Positives = 175/373 (46%), Gaps = 34/373 (9%)
Query: 393 IDECADPGSCSQICI-NEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIR 449
++ CA CS +C+ + +G + C C +G++ P D C + P L+ R+H I
Sbjct: 1701 VNPCAF-SRCSHLCLLSSQGPHFYSCVCPSGWSLSP-DLLNC-LRDDQPFLITVRQHIIF 1757
Query: 450 KISLDHHEMV--AIVNDTKSATALDYVFRTG--MIFWSDVNDEKIYKAPIDEGTQRTVVI 505
ISL+ A+V LD F I+W + N +I++ D GT RTV
Sbjct: 1758 GISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-NPGEIHRVKTD-GTNRTVFA 1815
Query: 506 GEQLI-TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMR--KILIRDR-----LEEPRA 557
++ S LA+DW+ +LY T+ IE+ L G++R K LI + + P
Sbjct: 1816 SISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIG 1875
Query: 558 IALNPLEGWMFWTDWGQ---VP-KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
I ++P G ++W+D G VP KI A MDG+ T+ + +++ +TLD+ Q++YW
Sbjct: 1876 ITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQKLYW 1935
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
I N DG+ R +++H L HP+ I + ++Y+TD + R +K G
Sbjct: 1936 AVTGRGVIERGNVDGTDRMILVHQ---LSHPWGIAVHDSFLYYTDEQYEVIERVDKATG- 1991
Query: 674 DVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
I + N + VYH + N C+ C +CLP P SCAC
Sbjct: 1992 -ANKIVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVP-----GGLFSCAC 2045
Query: 734 PNGLKLLPDDQMC 746
G KL PD++ C
Sbjct: 2046 ATGFKLNPDNRSC 2058
Score = 131 bits (316), Expect = 1e-29
Identities = 88/276 (31%), Positives = 124/276 (44%), Gaps = 23/276 (8%)
Query: 144 ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQCISA 201
E C + FTC NG+CI W E++ C TC P + F+C +G+C+
Sbjct: 2698 ERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTA-FTCANGRCVQY 2756
Query: 202 WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXX 261
+ CD DC DGSDE GC+ R +TEF CN+R C+ R ++
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCL----FRDCNATTEFMCNNR-RCIPREFICNGVDNCHDNNT 2811
Query: 262 EALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
+ C TC+ +C + + CIP C+G DC D SDE N T T +EF
Sbjct: 2812 SDEKNCPDR-TCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDE-NPTYCTTHTCSSSEF 2869
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGC-SQRCVDTPIGYYCD 377
C G CIP CD+ DC + DEP CG +E C + C RC+ P + CD
Sbjct: 2870 QCASGRCIPQHWYCDQETDCFDASDEPAS-CGHSERTCLADEFKCDGGRCI--PSEWICD 2926
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQ---ICINEK 410
G + + ED +CS +C+N++
Sbjct: 2927 ---GDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDR 2959
Score = 124 bits (300), Expect = 9e-28
Identities = 76/249 (30%), Positives = 104/249 (41%), Gaps = 14/249 (5%)
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSH 190
C + E C F C NG+C+ ++ E C T TC S
Sbjct: 1013 CEGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCS-SSA 1071
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
F+C G+CI A W CD DC DGSDE C + + C+ T++ C D C+ + WV
Sbjct: 1072 FTCGHGECIPAHWRCDKRNDCVDGSDEHNCPT--HAPASCLDTQYTC-DNHQCISKNWVC 1128
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C TC+ QF C +H CI + C+G KDC DGSDE C
Sbjct: 1129 DTDNDCGDGSDE--KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLN 1186
Query: 311 KTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQRCV 368
T ++F C G CI ++ CD DC + DE C + C + +
Sbjct: 1187 CT----ASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGI 1242
Query: 369 DTPIGYYCD 377
P + CD
Sbjct: 1243 CIPNFWECD 1251
Score = 117 bits (282), Expect = 1e-25
Identities = 100/339 (29%), Positives = 136/339 (40%), Gaps = 31/339 (9%)
Query: 113 CRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXX 171
C KPG T C D+ S C C S +F C N KCI + W
Sbjct: 3480 CLIKPGG-KGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDC 3538
Query: 172 XXXXXEVK-CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPC 230
E+ CP C+ F C+DG C S C+ +C DGSDE + C
Sbjct: 3539 SDGSDELALCPQRFCR-LGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCE---NHHC 3594
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGAL 290
S E++C ++ C+ +W E C TCR QF+C + CIP A
Sbjct: 3595 DSNEWQCANK-RCIPESWQCDTFNDCEDNSDEDSSHCASR-TCRPGQFRCANGRCIPQAW 3652
Query: 291 YCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEP 347
C+ DC D SDE C +CD TEF C CIP VC+ DC + DE
Sbjct: 3653 KCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE- 3711
Query: 348 RDRCGENECEK-NNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQI 405
C E C + C + C+ P+ + CD + DN D + CA P C++
Sbjct: 3712 -QGCEERTCHPVGDFRCKNHHCI--PLRWQCDGQNDCG--DN---SDEENCA-PRECTES 3762
Query: 406 ---CINEK---GTFKCECHTGYARDPRDRTRCKATEGHP 438
C+N++ + C+ H D D C+ HP
Sbjct: 3763 EFRCVNQQCIPSRWICD-HYNDCGDNSDERDCEMRTCHP 3800
Score = 64.1 bits (149), Expect = 2e-09
Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY-CDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEK 410
N C N C Q C+ P G + C C G+KL DNR+C + S I + +
Sbjct: 2020 NGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLE 2079
Query: 411 GTFKCECHTGYARDPRDRTRCKATEGHPSLLF-------ARKHDIRKISLDHHEMVAIV- 462
+ E A R+ + + A + IR+I D ++ IV
Sbjct: 2080 LSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVT 2139
Query: 463 ----NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ A+D+V + F + E + + T R V++ + + VD
Sbjct: 2140 HGIGENGVRGIAVDWV-AGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVD 2198
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+L+W D G IE S L R +L+ + + PR +A++ +G+++W D +
Sbjct: 2199 PKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVD-DSLDI 2257
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTI 621
I R ++G + S ++ Y ++P + + + WVD + I
Sbjct: 2258 IARIRINGEN-SEVIRYGSRYPTPYGITVFENSIIWVDRNLKKI 2300
Score = 39.9 bits (89), Expect = 0.033
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDC--EKGYKLIDNRTCEDIDECADPGSCSQI 405
+ +C N CE+ NGGCS C P G C C E + L +NR +D G+ S
Sbjct: 2648 KQQCN-NPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFT 2706
Query: 406 CIN 408
C N
Sbjct: 2707 CSN 2709
Score = 34.3 bits (75), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY---CDCEKGYKLIDNRTC 390
N C +NNGGCS C P G + CDC G D + C
Sbjct: 2344 NPCLENNGGCSHLCFALP-GLHTPKCDCAFGTLQSDGKNC 2382
>AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein.
Length = 3881
Score = 539 bits (1330), Expect = e-152
Identities = 290/742 (39%), Positives = 388/742 (52%), Gaps = 35/742 (4%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C F CK GRC+P + CD DC D+SDE +C C F C G CIP
Sbjct: 252 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQ--LCGTLNNTCSSSAFTC-GHGECIPA 308
Query: 83 SWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
WRCD DC DGSDEH C A C ++TC +C+ W+CD + DC DGSDE
Sbjct: 309 HWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNH--QCISKNWVCDTDNDCGDGSDE 366
Query: 140 KACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG- 196
K CN ETC+ +F C N +CI + +V EV C C S F C G
Sbjct: 367 KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVL-NCTA-SQFKCASGD 424
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+CI CDG DC+D SDE GC + P C S EF+C + C+ W
Sbjct: 425 KCIGVTNRCDGVFDCSDNSDEAGCPTRPP--GMCHSDEFQCQEDGICIPNFWECDGHPDC 482
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E C TC F C + +CI A C+ DC D SDE +C Q C
Sbjct: 483 LYGSDEH-NACVPK-TCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPS 540
Query: 317 RTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
++ C G +C+ LS VCD DCPN DE C N C NGGC+ CV P G
Sbjct: 541 -WQWQCLGHNICVNLSVVCDGIFDCPNGTDES-PLCNGNSCSDFNGGCTHECVQEPFGAK 598
Query: 376 CDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
C C G+ L D++TCEDIDEC GSCSQ C N +G+F+C C TGY + RT CK T
Sbjct: 599 CLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRT-CKVT 657
Query: 435 EGHPSLLFARKHD---IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIY 491
LL + ++ H + ++V + A+D+ +G IFWSD K +
Sbjct: 658 ASESLLLLVASQNKIIADSVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTW 717
Query: 492 KAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDR 551
A GT R VV +I ++ +A+DWV +LYWTD IE+S + G+ R +LI
Sbjct: 718 SA-FQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKN 776
Query: 552 LEEPRAIALNPL--EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQ 609
L PR +AL+P E +FW+DWG P+IERA MDGS R+ IV + WP GLT+D +
Sbjct: 777 LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNR 836
Query: 610 RVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANK 669
+Y++D+ ++ + C+Y+G RR ++ S ++RHP+++T FED VYWTD V RANK
Sbjct: 837 LLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANK 896
Query: 670 FNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRV 729
++G + + + +Q P+ I HP +QP+ VN CA CSHLCL + + GP+
Sbjct: 897 WHGGNQSVV--MYNIQWPLGIVAVHPSKQPNSVNPCAF--SRCSHLCLLSSQ-GPHF--Y 949
Query: 730 SCACPNGLKLLPDDQMCVEDSK 751
SC CP+G L PD C+ D +
Sbjct: 950 SCVCPSGWSLSPDLLNCLRDDQ 971
Score = 485 bits (1196), Expect = e-136
Identities = 266/748 (35%), Positives = 374/748 (50%), Gaps = 53/748 (7%)
Query: 21 RTCTSS-EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R C ++ EF C RCIP + C+ +C D++ D C CQ +C + +C
Sbjct: 2004 RDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCP--DRTCQSGYTKCHNSNIC 2061
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
IPR + CD DC D SDE+ C C EF C G C+P W CD DC D S
Sbjct: 2062 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS--GRCIPQHWYCDQETDCFDAS 2119
Query: 138 DEKA-CNE---TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK---CPTPTCQPQSH 190
DE A C TC +DEF C G+CI W+ E K C C S
Sbjct: 2120 DEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS-DSE 2178
Query: 191 FSCT-----DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D +CI W CDGDVDC DG DE + R C EF C + C+
Sbjct: 2179 FLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDE----NQNCTRRTCSENEFTCGYGL-CIP 2233
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE- 304
+ + E L + TC+ +QF C++ CI C+ DC DGSDE
Sbjct: 2234 KIFRCDRHNDCGDYSDERGCLYQ---TCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDEL 2290
Query: 305 -YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGG 362
+ C + C EF C G CI + K+C+ DC + DE CG NEC + + G
Sbjct: 2291 MHLCHTPEPTCPPH-EFKCDNGRCIEMMKLCNHLDDCLDNSDEKG--CGINECHDPSISG 2347
Query: 363 CSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTG 420
C C DT +YC C GYKL+ D RTC DIDEC + P CSQ C N G++ C+C G
Sbjct: 2348 CDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPG 2407
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMI 480
Y R+P +T + + P L+F+ ++ +R +++D + I+ + ALD+ +
Sbjct: 2408 YLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRL 2467
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
+W D + I + +++ T + +I +L ++ LAVDWV LYW D + + +SDL
Sbjct: 2468 YWIDTQRQVIERMFLNK-TNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLN 2526
Query: 541 GNMRKILIRDRLE--------EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
G R++L + ++ PR +AL+P G+++W DWG I R GMDG+++S I+
Sbjct: 2527 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVII 2586
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S ++WPNG+T+D +YW DA + I + +G R + L HPF+IT FED
Sbjct: 2587 STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFED 2644
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+YWTDW+ V + NK++G + + T +T P IHVYHPYRQP N C NG C
Sbjct: 2645 TIYWTDWNTRTVEKGNKYDGSNRQ--TLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGC 2702
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLL 740
SHLCL P +C CP+ + L
Sbjct: 2703 SHLCL----IKPGGKGFTCECPDDFRTL 2726
Score = 470 bits (1159), Expect = e-132
Identities = 271/747 (36%), Positives = 372/747 (49%), Gaps = 52/747 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGL 78
SRTC +FRC GRCIP +WKCD + DC D SDE C ++ +C + F C ++
Sbjct: 2858 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 2917
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP+ C+ DC D SDE CE C P +F C K C+PL W CD DC D S
Sbjct: 2918 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC--KNHHCIPLRWQCDGQNDCGDNS 2975
Query: 138 DEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
DE+ C C EF C N +CI RW+ E C TC P+ +F CT G
Sbjct: 2976 DEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPE-YFQCTSG 3034
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
C+ + CDG DC D SDE C + + C +T FEC + + C+ W
Sbjct: 3035 HCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHV-CIPPYWKCDGDDDC 3093
Query: 257 XXXXXEALELCRGNVTCRL-DQFQCKDHSCIPGALYCNGVKDCPDGSD--EYNCTRQKTI 313
E L LC +V C ++F+C ++ CI CNGV DC DG+D E +C +
Sbjct: 3094 GDGSDEELHLCL-DVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPK 3152
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG-ENECEKNNGGCSQRCVD-TP 371
E+ CG G CIP VCD DC ++ DE G E C +N C Q C
Sbjct: 3153 PCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI--CEQNCTQLNE 3210
Query: 372 IGYYCDCEKGYK--LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-ARDPRDR 428
G+ C C G++ + D +C DI+EC G+C Q C N KG+++C C G+ + R
Sbjct: 3211 GGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRPG 3270
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVF---RTGM-IFWSD 484
RC A P LL IRK +L + D + A+DY + G+ + +
Sbjct: 3271 KRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPKDIGLSVVYYT 3330
Query: 485 VNDE--------KIYKAPIDEG----TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
V E + Y + G Q + + ++ DG+AVDWV H+YW+D +
Sbjct: 3331 VRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNK 3390
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
IE++ L G RK LI L++P AIA+NP G MFWTDWG+ PKIE A M+G R+ +V
Sbjct: 3391 RIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKIESAWMNGEDRNILV 3450
Query: 593 SYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFE 651
D+ WP GL++D L R+YW D K + I + YDG+ RR+I + E + +P+S+ FE
Sbjct: 3451 FEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVI--AKEAM-NPYSLDIFE 3507
Query: 652 DWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVIHVYHPYRQPDGV-NHCAAVN 709
D +YW +K V++ NKF GK + + L + ++H R V N C +
Sbjct: 3508 DQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---VRIFHQLRYNKSVPNLCKQI- 3563
Query: 710 GHCSHLCLPAPRFGPNSPRVSCACPNG 736
CSHLCL P SCACP G
Sbjct: 3564 --CSHLCLLRP------GGYSCACPQG 3582
Score = 252 bits (618), Expect = 3e-66
Identities = 199/669 (29%), Positives = 297/669 (44%), Gaps = 98/669 (14%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ + TC+SSEF+C +GRCIP W CD E DC D+SDE P C ++ C F+C
Sbjct: 2084 YCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDE-PASCGHSERTCLADEFKC-DG 2141
Query: 77 GLCIPRSWRCDATADCPDGSDE---HQCEVEACGPEEFTC---RGKPGECVPLTWMCDDN 130
G CIP W CD DC D SDE HQC+ + C EF C R C+P +W+CD +
Sbjct: 2142 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGD 2201
Query: 131 PDCSDGSDE--KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC+DG DE TC +EFTCG G CI + E C TCQ Q
Sbjct: 2202 VDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQ-Q 2260
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRA 247
+ F+C +G+CIS + CD D DC DGSDE + TP+ C EF+C D C+
Sbjct: 2261 NQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE--PTCPPHEFKC-DNGRCI--- 2314
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS---DE 304
E ++LC LD C D+S G G+ +C D S +
Sbjct: 2315 --------------EMMKLCN-----HLD--DCLDNSDEKGC----GINECHDPSISGCD 2349
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
+NCT D T F C C P K+ C + + EC + CS
Sbjct: 2350 HNCT------DTLTSFYCS---CRPGYKLMSDKRTCVDID----------ECTEMPFVCS 2390
Query: 365 QRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-- 421
Q+C + Y C C GY + D +TC + +P + + + + GY
Sbjct: 2391 QKCENVIGSYICKCAPGYLREPDGKTCRQ-NSNIEP----YLIFSNRYYLRNLTIDGYFY 2445
Query: 422 --ARDPRDRTRCKATEGHPSLLF---ARKHDIRKISLDHHEMVAIVNDTKSAT---ALDY 473
+ D + L+ ++ I ++ L+ I+N A A+D+
Sbjct: 2446 SLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDW 2505
Query: 474 VFRTGMIFWSDVNDEKIYKAPIDEGTQRTV----VIGEQLITSD---GLAVDWVYNHLYW 526
V R ++W D + ++ + ++ G +R + V D GLA+ Y +LYW
Sbjct: 2506 VSR--KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 2563
Query: 527 TDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
D GH +I + G + ++I +LE P I ++ ++W D + IE + ++G
Sbjct: 2564 ADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWAD-AHLGYIEYSDLEG 2622
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHP 644
HR T+ YD P+ + + +YW D T+ N YDGS R+ ++++T P
Sbjct: 2623 HHRHTV--YDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTT---HRP 2677
Query: 645 FSITTFEDW 653
F I + +
Sbjct: 2678 FDIHVYHPY 2686
Score = 221 bits (541), Expect = 6e-57
Identities = 145/433 (33%), Positives = 193/433 (44%), Gaps = 31/433 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
L E+ C S+E++C RCIP SW+CD DC D+SDED + C + C+ +F C +
Sbjct: 2813 LLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCAS--RTCRPGQFRC-A 2869
Query: 76 DGLCIPRSWRCDATADCPDGSDE--HQCEVEA--CGP-EEFTCRGKPGECVPLTWMCDDN 130
+G CIP++W+CD DC D SDE +C A C EF+C+ C+P +C+
Sbjct: 2870 NGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTN-YRCIPKWAVCNGV 2928
Query: 131 PDCSDGSDEKACNE-TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC D SDE+ C E TC +F C N CI +RW E C C +
Sbjct: 2929 DDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPREC-TE 2987
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
S F C + QCI + W CD DC D SDE C ++R+ C F+C CVH
Sbjct: 2988 SEFRCVNQQCIPSRWICDHYNDCGDNSDERDC----EMRT-CHPEYFQCTSG-HCVHSEL 3041
Query: 249 VXXXXXXXXXXXXEALELCR--GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
EA R C+ F+CK+H CIP C+G DC DGSDE
Sbjct: 3042 KCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEEL 3101
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE---NECEKNNGGC 363
C+ F C CI +VC+ DC + DE + C + C + C
Sbjct: 3102 HLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKC 3161
Query: 364 SQ-RCVDTPIGYYC-DCEKGYKLIDNRTCEDIDE--CADPGSCSQICIN-EKGTFKCECH 418
C+ P C D + D C E CA+ C Q C +G F C C
Sbjct: 3162 GNGHCI--PHDNVCDDADDCGDWSDELGCNKGKERTCAE-NICEQNCTQLNEGGFICSCT 3218
Query: 419 TGYARDPRDRTRC 431
G+ + DRT C
Sbjct: 3219 AGFETNVFDRTSC 3231
Score = 218 bits (533), Expect = 5e-56
Identities = 186/670 (27%), Positives = 268/670 (40%), Gaps = 59/670 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV---CTATKMVCQEYRFECLSDGL 78
TC+ + F C GRC+ S++CD DC D SDE + C AT F C ++
Sbjct: 1966 TCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATT------EFMC-NNRR 2018
Query: 79 CIPRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIPR + C+ +C D SDE C C C C+P ++CD + DC D
Sbjct: 2019 CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKCHNS-NICIPRVYLCDGDNDCGDN 2077
Query: 137 SDEK---ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE-VKC--PTPTCQPQSH 190
SDE TC S EF C +G+CI W E C TC
Sbjct: 2078 SDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCL-ADE 2136
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-NDR---ITCVHR 246
F C G+CI + W CDGD DC D SDE C +EF C NDR C+ +
Sbjct: 2137 FKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQ--NQNCSDSEFLCVNDRPPDRRCIPQ 2194
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
+WV E R TC ++F C CIP C+ DC D SDE
Sbjct: 2195 SWVCDGDVDCTDGYDENQNCTRR--TCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERG 2252
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC--GENECEKNNGGCS 364
C Q C ++ +F C G CI + VCD+ DC + DE C E C + C
Sbjct: 2253 CLYQ--TC-QQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCD 2309
Query: 365 Q-RCVDTP--IGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFKCECHT 419
RC++ + DC D + C I+EC DP C C + +F C C
Sbjct: 2310 NGRCIEMMKLCNHLDDCLDN---SDEKGC-GINECHDPSISGCDHNCTDTLTSFYCSCRP 2365
Query: 420 GYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRT 477
GY + D+ C + + F + + A + + T
Sbjct: 2366 GY-KLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNSNIE 2424
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELS 537
+ +S N + ID G ++++ E L L D V LYW DT IE
Sbjct: 2425 PYLIFS--NRYYLRNLTID-GYFYSLIL-EGLDNVVALDFDRVEKRLYWIDTQRQVIERM 2480
Query: 538 DLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVK 597
L ++ +I RL ++A++ + ++W D ++ + + ++G HR + + V
Sbjct: 2481 FLNKTNKETIINHRLPAAESLAVDWVSRKLYWLD-ARLDGLFVSDLNGGHRRMLAQHCVD 2539
Query: 598 W--------PNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
P GL L +YW D I DG+ + +I+ + + +I
Sbjct: 2540 ANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITID 2599
Query: 649 TFEDWVYWTD 658
D +YW D
Sbjct: 2600 YTNDLLYWAD 2609
Score = 217 bits (531), Expect = 9e-56
Identities = 132/369 (35%), Positives = 170/369 (46%), Gaps = 30/369 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +S F C GRCI WKCDN+ DC D SDE +VC C F C ++G C+
Sbjct: 1926 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCAL--HTCSPTAFTC-ANGRCVQY 1982
Query: 83 SWRCDATADCPDGSDEHQCEVEAC-GPEEFTCRGKPGECVPLTWMCDDNPDCSDG--SDE 139
S+RCD DC DGSDE C C EF C + C+P ++C+ +C D SDE
Sbjct: 1983 SYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNR--RCIPREFICNGVDNCHDNNTSDE 2040
Query: 140 KAC-NETCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTD 195
K C + TC+S C N CI ++ E C T TC S F C
Sbjct: 2041 KNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEFQCAS 2099
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI W+CD + DC D SDE S C++ EF+C D C+ W+
Sbjct: 2100 GRCIPQHWYCDQETDCFDASDEP--ASCGHSERTCLADEFKC-DGGRCIPSEWICDGDND 2156
Query: 256 XXXXXXEALELCRGNVTCRLDQFQC-----KDHSCIPGALYCNGVKDCPDGSDE-YNCTR 309
E N C +F C D CIP + C+G DC DG DE NCTR
Sbjct: 2157 CGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTR 2216
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
+ C + EF CG G+CIP CD+H DC ++ DE C C++N C RC+
Sbjct: 2217 R--TCSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDE--RGCLYQTCQQNQFTCQNGRCI 2271
Query: 369 DTPIGYYCD 377
+ CD
Sbjct: 2272 SKT--FVCD 2278
Score = 211 bits (515), Expect = 8e-54
Identities = 136/388 (35%), Positives = 182/388 (46%), Gaps = 38/388 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMVCQEYRFECLSDG 77
+ TC+SS F C G CIP W+CD DC D SDE PT A+ C + ++ C +
Sbjct: 290 NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPAS---CLDTQYTC-DNH 345
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CI ++W CD DC DGSDE C E C P +F C C+ L+++CD + DC DG
Sbjct: 346 QCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNH--RCIDLSFVCDGDKDCVDG 403
Query: 137 SDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSHFSC 193
SDE C C + +F C +G KCI + E CPT P F C
Sbjct: 404 SDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 463
Query: 194 -TDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
DG CI +W CDG DC GSDE CV PK C S+ F C D C+HRAW+
Sbjct: 464 QEDGICIPNFWECDGHPDCLYGSDEHNACV--PKT---CPSSYFHC-DNGNCIHRAWLCD 517
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C Q+QC H+ C+ ++ C+G+ DCP+G+DE
Sbjct: 518 RDNDCGDMSDEK-DCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE------ 570
Query: 311 KTICDKRTEFDCGGGM---CI--PLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCS 364
+C+ + D GG C+ P C + D C + +EC+ G CS
Sbjct: 571 SPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDS--KTCEDIDECD-ILGSCS 627
Query: 365 QRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
Q C + + C C+ GY L D RTC+
Sbjct: 628 QHCYNMRGSFRCSCDTGYMLESDGRTCK 655
Score = 193 bits (470), Expect = 2e-48
Identities = 115/335 (34%), Positives = 155/335 (46%), Gaps = 28/335 (8%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C+S++F C +CIP+ WKCD +KDCSD SDE + + C+ +F+C SDG C
Sbjct: 2738 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE---LALCPQRFCRLGQFQC-SDGNCTS 2793
Query: 82 RSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
C+A +CPDGSDE + CE C E+ C K C+P +W CD DC D SDE
Sbjct: 2794 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANK--RCIPESWQCDTFNDCEDNSDE 2851
Query: 140 KA---CNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPT--CQPQSHFS 192
+ + TCR +F C NG+CI W E +C + C + FS
Sbjct: 2852 DSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 2911
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C T+ +CI W C+G DC D SDE GC + R+ +F C + C+ W
Sbjct: 2912 CKTNYRCIPKWAVCNGVDDCRDNSDEQGC----EERTCHPVGDFRCKNH-HCIPLRWQCD 2966
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK 311
E E C C +F+C + CIP C+ DC D SDE +C +
Sbjct: 2967 GQNDCGDNSDE--ENCAPR-ECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDC--EM 3021
Query: 312 TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
C F C G C+ CD DC + DE
Sbjct: 3022 RTCHPE-YFQCTSGHCVHSELKCDGSADCLDASDE 3055
Score = 180 bits (439), Expect = 1e-44
Identities = 111/359 (30%), Positives = 174/359 (48%), Gaps = 21/359 (5%)
Query: 400 GSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD--- 454
G CS +C G T KC+C G + D C A L+FA + +R + LD
Sbjct: 1577 GGCSHLCFALPGLHTPKCDCAFGTLQS--DGKNC-AISTENFLIFALSNSLRSLHLDPEN 1633
Query: 455 HHEMVAIVNDTKSATALDYVFRTGMIFWSD---VNDEKIYKAPIDEGTQRTVVIGEQLIT 511
H +N ++ +LDY + I+++ +I A + G VI + T
Sbjct: 1634 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGT 1693
Query: 512 SDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
+DG+A DW+ +Y++D + I G+ R ++ R + +PRAI L+P +G+++W D
Sbjct: 1694 ADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIAR--VPKPRAIVLDPCQGYLYWAD 1751
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
W KIERA + G+ R IV+ + P+GLTLD +YWVDA + I G R
Sbjct: 1752 WDTHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQRIERSTLTGVDR 1811
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+I+++ H F +T + ++YWTD +YRANK++G A+T T+ L P I+
Sbjct: 1812 EVIVNAAV---HAFGLTLYGQYIYWTDLYTQRIYRANKYDGSGQIAMT-TNLLSQPRGIN 1867
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
++ N C NG CSH+C P GPN C L + + C+ D+
Sbjct: 1868 TVVKNQKQQCNNPCEQFNGGCSHICAP----GPNGAECQCPHEGNWYLANNRKHCIVDN 1922
Score = 171 bits (416), Expect = 8e-42
Identities = 108/318 (33%), Positives = 145/318 (45%), Gaps = 23/318 (7%)
Query: 65 VCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGECVPL 123
+C +F C ++ CIP W+CD DC DGSDE C C +F C G C
Sbjct: 2737 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQC--SDGNCTSP 2794
Query: 124 TWMCDDNPDCSDGSDEK--AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--V 178
+C+ + +C DGSDE C N C S+E+ C N +CI W E
Sbjct: 2795 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSS 2854
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCIS-TEF 235
C + TC+P F C +G+CI W CD D DC D SDE C+S+ + C + TEF
Sbjct: 2855 HCASRTCRP-GQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHL---CDNFTEF 2910
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C C+ + V E + C + F+CK+H CIP C+G
Sbjct: 2911 SCKTNYRCIPKWAVCNGVDDCRDNSDE--QGCEERTCHPVGDFRCKNHHCIPLRWQCDGQ 2968
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE 355
DC D SDE NC ++ C + +EF C CIP +CD + DC + DE RD C
Sbjct: 2969 NDCGDNSDEENCAPRE--CTE-SEFRCVNQQCIPSRWICDHYNDCGDNSDE-RD-CEMRT 3023
Query: 356 CEKNNGGC-SQRCVDTPI 372
C C S CV + +
Sbjct: 3024 CHPEYFQCTSGHCVHSEL 3041
Score = 161 bits (391), Expect = 8e-39
Identities = 81/249 (32%), Positives = 129/249 (51%), Gaps = 7/249 (2%)
Query: 501 RTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIAL 560
R ++ ++ + LA DW+ +LYWTD+ + I + L R+ +++ L PR++ +
Sbjct: 1 REILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQ-YLNNPRSVVV 59
Query: 561 NPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT 620
+P G++F+TDW + KI RA DGSH +++ + WPNGL +D R+YWVDA +
Sbjct: 60 HPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDK 119
Query: 621 ISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITS 680
I +DG RR + H E + HPF + F + +++TDW A+ R K +G ++ I S
Sbjct: 120 IEHSTFDGLDRRRLGH-IEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRS 178
Query: 681 THTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLL 740
+ + + + N NG CSH C P P F RV C CP G++L
Sbjct: 179 GIAYILHLKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPNF----QRV-CGCPYGMRLA 233
Query: 741 PDDQMCVED 749
+ C D
Sbjct: 234 SNHLTCEGD 242
Score = 156 bits (378), Expect = 3e-37
Identities = 118/409 (28%), Positives = 200/409 (48%), Gaps = 36/409 (8%)
Query: 380 KGYKLIDNRTC-EDIDECADP-GSCSQICINEKG-TFKCECHTGYARDPRDRTRCKATEG 436
+G ++ R E + C++ +C QIC+ G F C C TG+ +P +R+ C
Sbjct: 1231 RGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRS-CSPYNS 1289
Query: 437 HPSLLFARKHDIRKISL---DHHE-MVAIVNDTKSATALDYVFRTGMIFWSD-----VND 487
++ + IR SL DH E MV + ++A +D +G I+W D +D
Sbjct: 1290 F--IVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASD 1347
Query: 488 EKIYKAPIDEGTQRTVV---IGEQLITSDGLAVDWVYNHLYWTDT--GHNHIELSDLQGN 542
I + D + +V IGE + G+AVDWV +LY+T+ IE+ +
Sbjct: 1348 NAIRRIKPDGSSLMNIVTHGIGENGVR--GIAVDWVAGNLYFTNAFVSETLIEVLRINTT 1405
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGL 602
R++L++ ++ PR I ++P ++FW D+GQ PKIER+ +D ++R+ +VS + P GL
Sbjct: 1406 YRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGL 1465
Query: 603 TLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKT 662
+D VYWVD ++ I+ +G +I + + P+ IT FE+ + W D +
Sbjct: 1466 AVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSR-YPTPYGITVFENSIIWVDRNLK 1524
Query: 663 AVYRANKFNGKDVEAIT----STHTLQNPMVIHVYHPYRQPDGVNH--CAAVNGHCSHLC 716
+++A+K ++ E T + + L++ + R P VN+ C NG CSHLC
Sbjct: 1525 KIFQASK-EPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLC 1583
Query: 717 LPAPRFGPNSPRVSCACPNGLKLLPDDQMC-VEDSKYHFLPFYNNFRSI 764
P G ++P+ C C G L D + C + + N+ RS+
Sbjct: 1584 FALP--GLHTPK--CDCAFG-TLQSDGKNCAISTENFLIFALSNSLRSL 1627
Score = 146 bits (354), Expect = 3e-34
Identities = 81/207 (39%), Positives = 102/207 (49%), Gaps = 13/207 (6%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + TC S+F C RCI LS+ CD +KDC D SDE V + C +F+C S
Sbjct: 370 NSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCV-----LNCTASQFKCASGD 424
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVE---ACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
CI + RCD DC D SDE C C +EF C+ + G C+P W CD +PDC
Sbjct: 425 KCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGICIPNFWECDGHPDCL 483
Query: 135 DGSDE-KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHF 191
GSDE AC +TC S F C NG CI W+ E CPT P P +
Sbjct: 484 YGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQW 543
Query: 192 SCTDGQ-CISAWWHCDGDVDCADGSDE 217
C C++ CDG DC +G+DE
Sbjct: 544 QCLGHNICVNLSVVCDGIFDCPNGTDE 570
Score = 141 bits (342), Expect = 7e-33
Identities = 111/373 (29%), Positives = 175/373 (46%), Gaps = 34/373 (9%)
Query: 393 IDECADPGSCSQICI-NEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIR 449
++ CA CS +C+ + +G + C C +G++ P D C + P L+ R+H I
Sbjct: 927 VNPCAF-SRCSHLCLLSSQGPHFYSCVCPSGWSLSP-DLLNC-LRDDQPFLITVRQHIIF 983
Query: 450 KISLDHHEMV--AIVNDTKSATALDYVFRTG--MIFWSDVNDEKIYKAPIDEGTQRTVVI 505
ISL+ A+V LD F I+W + N +I++ D GT RTV
Sbjct: 984 GISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-NPGEIHRVKTD-GTNRTVFA 1041
Query: 506 GEQLI-TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMR--KILIRDR-----LEEPRA 557
++ S LA+DW+ +LY T+ IE+ L G++R K LI + + P
Sbjct: 1042 SISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIG 1101
Query: 558 IALNPLEGWMFWTDWGQ---VP-KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
I ++P G ++W+D G VP KI A MDG+ T+ + +++ +TLD+ Q++YW
Sbjct: 1102 ITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQKLYW 1161
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
I N DG+ R +++H L HP+ I + ++Y+TD + R +K G
Sbjct: 1162 AVTGRGVIERGNVDGTDRMILVHQ---LSHPWGIAVHDSFLYYTDEQYEVIERVDKATG- 1217
Query: 674 DVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
I + N + VYH + N C+ C +CLP P SCAC
Sbjct: 1218 -ANKIVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVP-----GGLFSCAC 1271
Query: 734 PNGLKLLPDDQMC 746
G KL PD++ C
Sbjct: 1272 ATGFKLNPDNRSC 1284
Score = 131 bits (316), Expect = 1e-29
Identities = 88/276 (31%), Positives = 124/276 (44%), Gaps = 23/276 (8%)
Query: 144 ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQCISA 201
E C + FTC NG+CI W E++ C TC P + F+C +G+C+
Sbjct: 1924 ERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTA-FTCANGRCVQY 1982
Query: 202 WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXX 261
+ CD DC DGSDE GC+ R +TEF CN+R C+ R ++
Sbjct: 1983 SYRCDYYNDCGDGSDEAGCL----FRDCNATTEFMCNNR-RCIPREFICNGVDNCHDNNT 2037
Query: 262 EALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
+ C TC+ +C + + CIP C+G DC D SDE N T T +EF
Sbjct: 2038 SDEKNCPDR-TCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDE-NPTYCTTHTCSSSEF 2095
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGC-SQRCVDTPIGYYCD 377
C G CIP CD+ DC + DEP CG +E C + C RC+ P + CD
Sbjct: 2096 QCASGRCIPQHWYCDQETDCFDASDEPAS-CGHSERTCLADEFKCDGGRCI--PSEWICD 2152
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQ---ICINEK 410
G + + ED +CS +C+N++
Sbjct: 2153 ---GDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDR 2185
Score = 124 bits (300), Expect = 9e-28
Identities = 76/249 (30%), Positives = 104/249 (41%), Gaps = 14/249 (5%)
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSH 190
C + E C F C NG+C+ ++ E C T TC S
Sbjct: 239 CEGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCS-SSA 297
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
F+C G+CI A W CD DC DGSDE C + + C+ T++ C D C+ + WV
Sbjct: 298 FTCGHGECIPAHWRCDKRNDCVDGSDEHNCPT--HAPASCLDTQYTC-DNHQCISKNWVC 354
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C TC+ QF C +H CI + C+G KDC DGSDE C
Sbjct: 355 DTDNDCGDGSDE--KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLN 412
Query: 311 KTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQRCV 368
T ++F C G CI ++ CD DC + DE C + C + +
Sbjct: 413 CT----ASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGI 468
Query: 369 DTPIGYYCD 377
P + CD
Sbjct: 469 CIPNFWECD 477
Score = 117 bits (282), Expect = 1e-25
Identities = 100/339 (29%), Positives = 136/339 (40%), Gaps = 31/339 (9%)
Query: 113 CRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXX 171
C KPG T C D+ S C C S +F C N KCI + W
Sbjct: 2706 CLIKPGG-KGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDC 2764
Query: 172 XXXXXEVK-CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPC 230
E+ CP C+ F C+DG C S C+ +C DGSDE + C
Sbjct: 2765 SDGSDELALCPQRFCR-LGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCE---NHHC 2820
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGAL 290
S E++C ++ C+ +W E C TCR QF+C + CIP A
Sbjct: 2821 DSNEWQCANK-RCIPESWQCDTFNDCEDNSDEDSSHCASR-TCRPGQFRCANGRCIPQAW 2878
Query: 291 YCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEP 347
C+ DC D SDE C +CD TEF C CIP VC+ DC + DE
Sbjct: 2879 KCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE- 2937
Query: 348 RDRCGENECEK-NNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQI 405
C E C + C + C+ P+ + CD + DN D + CA P C++
Sbjct: 2938 -QGCEERTCHPVGDFRCKNHHCI--PLRWQCDGQNDCG--DN---SDEENCA-PRECTES 2988
Query: 406 ---CINEK---GTFKCECHTGYARDPRDRTRCKATEGHP 438
C+N++ + C+ H D D C+ HP
Sbjct: 2989 EFRCVNQQCIPSRWICD-HYNDCGDNSDERDCEMRTCHP 3026
Score = 64.1 bits (149), Expect = 2e-09
Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY-CDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEK 410
N C N C Q C+ P G + C C G+KL DNR+C + S I + +
Sbjct: 1246 NGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLE 1305
Query: 411 GTFKCECHTGYARDPRDRTRCKATEGHPSLLF-------ARKHDIRKISLDHHEMVAIV- 462
+ E A R+ + + A + IR+I D ++ IV
Sbjct: 1306 LSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVT 1365
Query: 463 ----NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ A+D+V + F + E + + T R V++ + + VD
Sbjct: 1366 HGIGENGVRGIAVDWV-AGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVD 1424
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+L+W D G IE S L R +L+ + + PR +A++ +G+++W D +
Sbjct: 1425 PKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVD-DSLDI 1483
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTI 621
I R ++G + S ++ Y ++P + + + WVD + I
Sbjct: 1484 IARIRINGEN-SEVIRYGSRYPTPYGITVFENSIIWVDRNLKKI 1526
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 9/120 (7%)
Query: 478 GMIFWSD-VNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIEL 536
G +F++D KI +A D G+ VI L +GLA+DW + LYW D + IE
Sbjct: 64 GYLFFTDWFRPAKIMRAWSD-GSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEH 122
Query: 537 SDLQG-NMRKILIRDRLEEPRAIALNPLEGWMFWTDW--GQVPKIERAGMDGSHRSTIVS 593
S G + R++ +++ P +A+ +F+TDW G + ++ +A DG + I S
Sbjct: 123 STFDGLDRRRLGHIEQMTHPFGLAI--FGEHLFFTDWRLGAIIRVRKA--DGGEMTVIRS 178
Score = 39.9 bits (89), Expect = 0.033
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDC--EKGYKLIDNRTCEDIDECADPGSCSQI 405
+ +C N CE+ NGGCS C P G C C E + L +NR +D G+ S
Sbjct: 1874 KQQCN-NPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFT 1932
Query: 406 CIN 408
C N
Sbjct: 1933 CSN 1935
Score = 34.3 bits (75), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY---CDCEKGYKLIDNRTC 390
N C +NNGGCS C P G + CDC G D + C
Sbjct: 1570 NPCLENNGGCSHLCFALP-GLHTPKCDCAFGTLQSDGKNC 1608
Score = 33.5 bits (73), Expect = 2.9
Identities = 36/181 (19%), Positives = 77/181 (42%), Gaps = 7/181 (3%)
Query: 459 VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ N ++ +L + + + ++W+D + + I + + T+RTVV + L + V
Sbjct: 3 ILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVV--QYLNNPRSVVVH 60
Query: 519 WVYNHLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+L++TD I + G+ +I L P +A++ ++W D K
Sbjct: 61 PFAGYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVD-AYFDK 119
Query: 578 IERAGMDGSHRSTIVSYD-VKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILH 636
IE + DG R + + + P GL + + +++ D ++ I G ++
Sbjct: 120 IEHSTFDGLDRRRLGHIEQMTHPFGLA--IFGEHLFFTDWRLGAIIRVRKADGGEMTVIR 177
Query: 637 S 637
S
Sbjct: 178 S 178
>AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 537 bits (1326), Expect = e-152
Identities = 289/742 (38%), Positives = 387/742 (52%), Gaps = 35/742 (4%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C F CK GRC+P + CD DC D+SDE +C C F C G CIP
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQ--LCGTLNNTCSSSAFTC-GHGECIPA 1082
Query: 83 SWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
WRCD DC DGSDEH C A C ++TC +C+ W+CD + DC DGSDE
Sbjct: 1083 HWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNH--QCISKNWVCDTDNDCGDGSDE 1140
Query: 140 KACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG- 196
K CN ETC+ +F C N +CI + +V EV C C S F C G
Sbjct: 1141 KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVL-NCTA-SQFKCASGD 1198
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+CI CDG DC+D SDE GC + P C S EF+C + C+ W
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPP--GMCHSDEFQCQEDGICIPNFWECDGHPDC 1256
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDK 316
E C TC F C + +CI C+ DC D SDE +C Q C
Sbjct: 1257 LYGSDEH-NACVPK-TCPSSYFHCDNGNCIHRXWLCDRDNDCGDMSDEKDCPTQPFRCPS 1314
Query: 317 RTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
++ C G +C+ LS VCD DCPN DE C N C NGGC+ CV P G
Sbjct: 1315 -WQWQCLGHNICVNLSVVCDGIFDCPNGTDES-PLCNGNSCSDFNGGCTHECVQEPFGAK 1372
Query: 376 CDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
C C G+ L D++TCEDIDEC GSCSQ C N +G+F+C C TGY + RT CK T
Sbjct: 1373 CLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRT-CKVT 1431
Query: 435 EGHPSLLFARKHD---IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIY 491
LL + ++ H + ++V + A+D+ +G IFWSD K +
Sbjct: 1432 ASESLLLLVASQNKIIADSVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTW 1491
Query: 492 KAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDR 551
A GT R VV +I ++ +A+DWV +LYWTD IE+S + G+ R +LI
Sbjct: 1492 SA-FQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKN 1550
Query: 552 LEEPRAIALNPL--EGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQ 609
L PR +AL+P E +FW+DWG P+IERA MDGS R+ IV + WP GLT+D +
Sbjct: 1551 LTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNR 1610
Query: 610 RVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANK 669
+Y++D+ ++ + C+Y+G RR ++ S ++RHP+++T FED VYWTD V RANK
Sbjct: 1611 LLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANK 1670
Query: 670 FNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRV 729
++G + + + +Q P+ I HP +QP+ VN CA CSHLCL + + GP+
Sbjct: 1671 WHGGNQSVV--MYNIQWPLGIVAVHPSKQPNSVNPCAF--SRCSHLCLLSSQ-GPHF--Y 1723
Query: 730 SCACPNGLKLLPDDQMCVEDSK 751
SC CP+G L PD C+ D +
Sbjct: 1724 SCVCPSGWSLSPDLLNCLRDDQ 1745
Score = 485 bits (1196), Expect = e-136
Identities = 266/748 (35%), Positives = 374/748 (50%), Gaps = 53/748 (7%)
Query: 21 RTCTSS-EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R C ++ EF C RCIP + C+ +C D++ D C CQ +C + +C
Sbjct: 2778 RDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCP--DRTCQSGYTKCHNSNIC 2835
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
IPR + CD DC D SDE+ C C EF C G C+P W CD DC D S
Sbjct: 2836 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCTS--GRCIPQHWYCDQETDCFDAS 2893
Query: 138 DEKA-CNE---TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK---CPTPTCQPQSH 190
DE A C TC +DEF C G+CI W+ E K C C S
Sbjct: 2894 DEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCS-DSE 2952
Query: 191 FSCT-----DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D +CI W CDGDVDC DG DE + R C EF C + C+
Sbjct: 2953 FLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDE----NQNCTRRTCSENEFTCGYGL-CIP 3007
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE- 304
+ + E L + TC+ +QF C++ CI C+ DC DGSDE
Sbjct: 3008 KIFRCDRHNDCGDYSDERGCLYQ---TCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDEL 3064
Query: 305 -YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGG 362
+ C + C EF C G CI + K+C+ DC + DE CG NEC + + G
Sbjct: 3065 MHLCHTPEPTCPPH-EFKCDNGRCIEMMKLCNHLDDCLDNSDEKG--CGINECHDPSISG 3121
Query: 363 CSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTG 420
C C DT +YC C GYKL+ D RTC DIDEC + P CSQ C N G++ C+C G
Sbjct: 3122 CDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPG 3181
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMI 480
Y R+P +T + + P L+F+ ++ +R +++D + I+ + ALD+ +
Sbjct: 3182 YLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRL 3241
Query: 481 FWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
+W D + I + +++ T + +I +L ++ LAVDWV LYW D + + +SDL
Sbjct: 3242 YWIDTQRQVIERMFLNK-TNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLN 3300
Query: 541 GNMRKILIRDRLE--------EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
G R++L + ++ PR +AL+P G+++W DWG I R GMDG+++S I+
Sbjct: 3301 GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVII 3360
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S ++WPNG+T+D +YW DA + I + +G R + L HPF+IT FED
Sbjct: 3361 STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIFED 3418
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+YWTDW+ V + NK++G + + T +T P IHVYHPYRQP N C NG C
Sbjct: 3419 TIYWTDWNTRTVEKGNKYDGSNRQ--TLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGC 3476
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLL 740
SHLCL P +C CP+ + L
Sbjct: 3477 SHLCL----IKPGGKGFTCECPDDFRTL 3500
Score = 468 bits (1154), Expect = e-131
Identities = 270/747 (36%), Positives = 371/747 (49%), Gaps = 52/747 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGL 78
SRTC +FRC GRCIP +WKCD + DC D SDE C ++ +C + F C ++
Sbjct: 3632 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 3691
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP+ C+ DC D SDE CE C P +F C K C+PL W CD DC D S
Sbjct: 3692 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC--KNHHCIPLRWQCDGQNDCGDNS 3749
Query: 138 DEKAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDG 196
DE+ C C EF C N +CI RW+ E C TC P+ +F CT G
Sbjct: 3750 DEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPE-YFQCTSG 3808
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
C+ + CDG DC D SDE C + + C +T FEC + + C+ W
Sbjct: 3809 HCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHV-CIPPYWKCDGDDDC 3867
Query: 257 XXXXXEALELCRGNVTCRL-DQFQCKDHSCIPGALYCNGVKDCPDGSD--EYNCTRQKTI 313
E L LC +V C ++F+C ++ CI CNGV DC DG+D E +C +
Sbjct: 3868 GDGSDEELHLCL-DVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPK 3926
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG-ENECEKNNGGCSQRCVD-TP 371
E+ CG G CIP VCD DC ++ DE G E C +N C Q C
Sbjct: 3927 PCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI--CEQNCTQLNE 3984
Query: 372 IGYYCDCEKGYK--LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-ARDPRDR 428
G+ C C G++ + D +C DI+EC G+C Q C N KG+++C C G+ + R
Sbjct: 3985 GGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRPG 4044
Query: 429 TRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVF---RTGM-IFWSD 484
RC A P LL IRK +L + D + A+DY + G+ + +
Sbjct: 4045 KRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPXDIGLSVVYYT 4104
Query: 485 VNDE--------KIYKAPIDEG----TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
V E + Y + G Q + + ++ DG+AVDWV H+YW+D +
Sbjct: 4105 VRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNK 4164
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
IE++ L G RK LI L++P AIA+NP G MFWTDWG+ PK E A M+G R+ +V
Sbjct: 4165 RIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKXESAWMNGEDRNILV 4224
Query: 593 SYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFE 651
D+ WP GL++D L R+YW D K + I + YDG+ RR+I + E + +P+S+ FE
Sbjct: 4225 FEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVI--AKEAM-NPYSLDIFE 4281
Query: 652 DWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVIHVYHPYRQPDGV-NHCAAVN 709
D +YW +K V++ NKF GK + + L + ++H R V N C +
Sbjct: 4282 DQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---VRIFHQLRYNKSVPNLCKQI- 4337
Query: 710 GHCSHLCLPAPRFGPNSPRVSCACPNG 736
CSHLCL P SCACP G
Sbjct: 4338 --CSHLCLLRP------GGYSCACPQG 4356
Score = 433 bits (1067), Expect = e-120
Identities = 240/704 (34%), Positives = 341/704 (48%), Gaps = 38/704 (5%)
Query: 61 ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGEC 120
A+ C F C S G CIP WRCD T DC D +DE C V C F C+ + G+C
Sbjct: 23 ASGQECDSAHFRCGS-GHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSE-GQC 80
Query: 121 VPLTWMCDDNPDCSDGSDEKA-CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEV 178
+P +W+CD + DC DGSDE+ C++ TC S + TC NG+CI + E
Sbjct: 81 IPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADEN 140
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECN 238
C PTC+ +C +G C + CD VDC D SDE+ C C+ EF C
Sbjct: 141 DCQYPTCE---QLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI------CLHNEFSCG 191
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ C+ RA+V E C TC QF C CI C+G DC
Sbjct: 192 NG-ECIPRAYVCDHDNDCQDGSDE--HACN-YPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 299 PDGSDEYNCT---RQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR---- 350
D DE C C R E+ C G CI + KVCD +DCP EDE
Sbjct: 248 KDNGDEDGCESGPHDVHKCSPR-EWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGSCSQICIN 408
C C N C +C +TP G C C GY + D+RTC + D+C G C Q C +
Sbjct: 307 CSMTLCSALN--CQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCES 364
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
G C C GY + + + G S++F+ D+ + +V
Sbjct: 365 RPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRG 424
Query: 469 TALDYVFRTGM--IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYW 526
A+ F + +FW+D K++ I+ G V+ + T + LAVDWV N +Y
Sbjct: 425 VAVGVAFHYHLQRVFWTDTVQNKVFSVDIN-GLNIQEVLNVSVETPENLAVDWVNNKIYL 483
Query: 527 TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV---PKIERAGM 583
+T N I++ +L G+ R LI + L PR IA++P G++F++DW + PK+ERA M
Sbjct: 484 VETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFM 543
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRH 643
DGS+R +V + WP G+TLD++ +RVYWVD++ + I + YDG R+ ++H ++ H
Sbjct: 544 DGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPH 603
Query: 644 PFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVN 703
PF ++ FE V++TDW K AV +ANKF + + P + VYH RQP N
Sbjct: 604 PFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASL--RPYGVTVYHSLRQPYATN 661
Query: 704 HCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C NG C +C+ + R + C C G +L D++ C+
Sbjct: 662 PCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI 705
Score = 252 bits (618), Expect = 3e-66
Identities = 199/669 (29%), Positives = 297/669 (44%), Gaps = 98/669 (14%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ + TC+SSEF+C +GRCIP W CD E DC D+SDE P C ++ C F+C
Sbjct: 2858 YCTTHTCSSSEFQCTSGRCIPQHWYCDQETDCFDASDE-PASCGHSERTCLADEFKC-DG 2915
Query: 77 GLCIPRSWRCDATADCPDGSDE---HQCEVEACGPEEFTC---RGKPGECVPLTWMCDDN 130
G CIP W CD DC D SDE HQC+ + C EF C R C+P +W+CD +
Sbjct: 2916 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGD 2975
Query: 131 PDCSDGSDE--KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC+DG DE TC +EFTCG G CI + E C TCQ Q
Sbjct: 2976 VDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQ-Q 3034
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRA 247
+ F+C +G+CIS + CD D DC DGSDE + TP+ C EF+C D C+
Sbjct: 3035 NQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE--PTCPPHEFKC-DNGRCI--- 3088
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS---DE 304
E ++LC LD C D+S G G+ +C D S +
Sbjct: 3089 --------------EMMKLCN-----HLD--DCLDNSDEKGC----GINECHDPSISGCD 3123
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
+NCT D T F C C P K+ C + + EC + CS
Sbjct: 3124 HNCT------DTLTSFYCS---CRPGYKLMSDKRTCVDID----------ECTEMPFVCS 3164
Query: 365 QRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-- 421
Q+C + Y C C GY + D +TC + +P + + + + GY
Sbjct: 3165 QKCENVIGSYICKCAPGYLREPDGKTCRQ-NSNIEP----YLIFSNRYYLRNLTIDGYFY 3219
Query: 422 --ARDPRDRTRCKATEGHPSLLF---ARKHDIRKISLDHHEMVAIVNDTKSAT---ALDY 473
+ D + L+ ++ I ++ L+ I+N A A+D+
Sbjct: 3220 SLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDW 3279
Query: 474 VFRTGMIFWSDVNDEKIYKAPIDEGTQRTV----VIGEQLITSD---GLAVDWVYNHLYW 526
V R ++W D + ++ + ++ G +R + V D GLA+ Y +LYW
Sbjct: 3280 VSR--KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 527 TDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
D GH +I + G + ++I +LE P I ++ ++W D + IE + ++G
Sbjct: 3338 ADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWAD-AHLGYIEYSDLEG 3396
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRHP 644
HR T+ YD P+ + + +YW D T+ N YDGS R+ ++++T P
Sbjct: 3397 HHRHTV--YDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTT---HRP 3451
Query: 645 FSITTFEDW 653
F I + +
Sbjct: 3452 FDIHVYHPY 3460
Score = 237 bits (580), Expect = 1e-61
Identities = 192/666 (28%), Positives = 292/666 (43%), Gaps = 70/666 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + C S+ FRC +G CIP W+CD KDCSD +DE C + CQ+ F+C S+G
Sbjct: 23 ASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAV--VTCQQGYFKCQSEG 78
Query: 78 LCIPRSWRCDATADCPDGSDEHQ-CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP SW CD DC DGSDE Q C C + TC G+C+P + CD DC DG
Sbjct: 79 QCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSN--GQCIPSEYRCDHVRDCPDG 136
Query: 137 SDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
+DE C TC ++ TC NG C E+ C T C + FSC +
Sbjct: 137 ADENDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDEINC-TEICL-HNEFSCGN 192
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI + CD D DC DGSDE C + P C +F C C+++ WV
Sbjct: 193 GECIPRAYVCDHDNDCQDGSDEHAC-NYP----TCGGYQFTCPSG-RCIYQNWVCDGEDD 246
Query: 256 XXXXXXE-ALELCRGNV-TCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK- 311
E E +V C ++ C + CI C+G+ DCP DE N + K
Sbjct: 247 CKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 312 ---TICDK-RTEFDCG----GGMCIPLSKVCDKHVD---CPNFEDEPRDRCGENECEKNN 360
T+C ++ C GG C H D C F+D C+
Sbjct: 307 CSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDD----------CQ-IW 355
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG 420
G C Q+C P + C CE+GY L + C+ D G S I N + + H
Sbjct: 356 GICDQKCESRPGRHLCHCEEGYILERGQYCKANDSF---GEASIIFSNGRDLLIGDIHGR 412
Query: 421 YAR---DPRDRTRCKATEGHPSL--LFARKHDIRKI------SLDHHEMVAIVNDTKSAT 469
R + ++R H L +F K+ L+ E++ + +T
Sbjct: 413 SFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENL 472
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTD- 528
A+D+V I+ + +I +D G+ R +I E L G+AVD +L+++D
Sbjct: 473 AVDWV--NNKIYLVETKVNRIDMVNLD-GSYRVTLITENLGHPRGIAVDPTVGYLFFSDW 529
Query: 529 ---TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
+G +E + + G+ RK L++ +L P + L+ + ++W D + IE DG
Sbjct: 530 ESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVD-SRFDYIETVTYDG 588
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHP 644
R T+V P+ + L +V++ D KM + + + + ++ ++ LR P
Sbjct: 589 IQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQAS--LR-P 645
Query: 645 FSITTF 650
+ +T +
Sbjct: 646 YGVTVY 651
Score = 221 bits (541), Expect = 6e-57
Identities = 145/433 (33%), Positives = 193/433 (44%), Gaps = 31/433 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
L E+ C S+E++C RCIP SW+CD DC D+SDED + C + C+ +F C +
Sbjct: 3587 LLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCAS--RTCRPGQFRC-A 3643
Query: 76 DGLCIPRSWRCDATADCPDGSDE--HQCEVEA--CGP-EEFTCRGKPGECVPLTWMCDDN 130
+G CIP++W+CD DC D SDE +C A C EF+C+ C+P +C+
Sbjct: 3644 NGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTN-YRCIPKWAVCNGV 3702
Query: 131 PDCSDGSDEKACNE-TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC D SDE+ C E TC +F C N CI +RW E C C +
Sbjct: 3703 DDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPREC-TE 3761
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
S F C + QCI + W CD DC D SDE C ++R+ C F+C CVH
Sbjct: 3762 SEFRCVNQQCIPSRWICDHYNDCGDNSDERDC----EMRT-CHPEYFQCTSG-HCVHSEL 3815
Query: 249 VXXXXXXXXXXXXEALELCR--GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
EA R C+ F+CK+H CIP C+G DC DGSDE
Sbjct: 3816 KCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEEL 3875
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE---NECEKNNGGC 363
C+ F C CI +VC+ DC + DE + C + C + C
Sbjct: 3876 HLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKC 3935
Query: 364 SQ-RCVDTPIGYYC-DCEKGYKLIDNRTCEDIDE--CADPGSCSQICIN-EKGTFKCECH 418
C+ P C D + D C E CA+ C Q C +G F C C
Sbjct: 3936 GNGHCI--PHDNVCDDADDCGDWSDELGCNKGKERTCAE-NICEQNCTQLNEGGFICSCT 3992
Query: 419 TGYARDPRDRTRC 431
G+ + DRT C
Sbjct: 3993 AGFETNVFDRTSC 4005
Score = 219 bits (536), Expect = 2e-56
Identities = 133/369 (36%), Positives = 171/369 (46%), Gaps = 30/369 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +S F C GRCI WKCDN+ DC D SDE +VC C F C ++G C+
Sbjct: 2700 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCAL--HTCSPTAFTC-ANGRCVQY 2756
Query: 83 SWRCDATADCPDGSDEHQCEVEAC-GPEEFTCRGKPGECVPLTWMCDDNPDCSDG--SDE 139
S+RCD DC DGSDE C C EF C + C+P ++C+ +C D SDE
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNR--RCIPREFICNGVDNCHDNNTSDE 2814
Query: 140 KAC-NETCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTD 195
K C + TC+S C N CI ++ E C T TC S F CT
Sbjct: 2815 KNCPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEFQCTS 2873
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI W+CD + DC D SDE S C++ EF+C D C+ W+
Sbjct: 2874 GRCIPQHWYCDQETDCFDASDEP--ASCGHSERTCLADEFKC-DGGRCIPSEWICDGDND 2930
Query: 256 XXXXXXEALELCRGNVTCRLDQFQC-----KDHSCIPGALYCNGVKDCPDGSDE-YNCTR 309
E N C +F C D CIP + C+G DC DG DE NCTR
Sbjct: 2931 CGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGYDENQNCTR 2990
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
+ C + EF CG G+CIP CD+H DC ++ DE C C++N C RC+
Sbjct: 2991 R--TCSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDE--RGCLYQTCQQNQFTCQNGRCI 3045
Query: 369 DTPIGYYCD 377
+ CD
Sbjct: 3046 SKT--FVCD 3052
Score = 217 bits (531), Expect = 9e-56
Identities = 186/670 (27%), Positives = 268/670 (40%), Gaps = 59/670 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV---CTATKMVCQEYRFECLSDGL 78
TC+ + F C GRC+ S++CD DC D SDE + C AT F C ++
Sbjct: 2740 TCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATT------EFMC-NNRR 2792
Query: 79 CIPRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIPR + C+ +C D SDE C C C C+P ++CD + DC D
Sbjct: 2793 CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKCHNS-NICIPRVYLCDGDNDCGDN 2851
Query: 137 SDEK---ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE-VKC--PTPTCQPQSH 190
SDE TC S EF C +G+CI W E C TC
Sbjct: 2852 SDENPTYCTTHTCSSSEFQCTSGRCIPQHWYCDQETDCFDASDEPASCGHSERTCL-ADE 2910
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-NDR---ITCVHR 246
F C G+CI + W CDGD DC D SDE C +EF C NDR C+ +
Sbjct: 2911 FKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQ--NQNCSDSEFLCVNDRPPDRRCIPQ 2968
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYN 306
+WV E R TC ++F C CIP C+ DC D SDE
Sbjct: 2969 SWVCDGDVDCTDGYDENQNCTRR--TCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERG 3026
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC--GENECEKNNGGCS 364
C Q C ++ +F C G CI + VCD+ DC + DE C E C + C
Sbjct: 3027 CLYQ--TC-QQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCD 3083
Query: 365 Q-RCVDTP--IGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFKCECHT 419
RC++ + DC D + C I+EC DP C C + +F C C
Sbjct: 3084 NGRCIEMMKLCNHLDDCLDN---SDEKGC-GINECHDPSISGCDHNCTDTLTSFYCSCRP 3139
Query: 420 GYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRT 477
GY + D+ C + + F + + A + + T
Sbjct: 3140 GY-KLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNSNIE 3198
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELS 537
+ +S N + ID G ++++ E L L D V LYW DT IE
Sbjct: 3199 PYLIFS--NRYYLRNLTID-GYFYSLIL-EGLDNVVALDFDRVEKRLYWIDTQRQVIERM 3254
Query: 538 DLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVK 597
L ++ +I RL ++A++ + ++W D ++ + + ++G HR + + V
Sbjct: 3255 FLNKTNKETIINHRLPAAESLAVDWVSRKLYWLD-ARLDGLFVSDLNGGHRRMLAQHCVD 3313
Query: 598 W--------PNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
P GL L +YW D I DG+ + +I+ + + +I
Sbjct: 3314 ANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITID 3373
Query: 649 TFEDWVYWTD 658
D +YW D
Sbjct: 3374 YTNDLLYWAD 3383
Score = 209 bits (511), Expect = 2e-53
Identities = 135/388 (34%), Positives = 181/388 (46%), Gaps = 38/388 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMVCQEYRFECLSDG 77
+ TC+SS F C G CIP W+CD DC D SDE PT A+ C + ++ C +
Sbjct: 1064 NNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTHAPAS---CLDTQYTC-DNH 1119
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CI ++W CD DC DGSDE C E C P +F C C+ L+++CD + DC DG
Sbjct: 1120 QCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNH--RCIDLSFVCDGDKDCVDG 1177
Query: 137 SDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSHFSC 193
SDE C C + +F C +G KCI + E CPT P F C
Sbjct: 1178 SDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQC 1237
Query: 194 -TDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
DG CI +W CDG DC GSDE CV PK C S+ F C D C+HR W+
Sbjct: 1238 QEDGICIPNFWECDGHPDCLYGSDEHNACV--PKT---CPSSYFHC-DNGNCIHRXWLCD 1291
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C Q+QC H+ C+ ++ C+G+ DCP+G+DE
Sbjct: 1292 RDNDCGDMSDEK-DCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE------ 1344
Query: 311 KTICDKRTEFDCGGGM---CI--PLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCS 364
+C+ + D GG C+ P C + D C + +EC+ G CS
Sbjct: 1345 SPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDS--KTCEDIDECD-ILGSCS 1401
Query: 365 QRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
Q C + + C C+ GY L D RTC+
Sbjct: 1402 QHCYNMRGSFRCSCDTGYMLESDGRTCK 1429
Score = 198 bits (483), Expect = 6e-50
Identities = 115/365 (31%), Positives = 183/365 (50%), Gaps = 22/365 (6%)
Query: 396 CADP-GSCSQICI------NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI 448
C D G C Q+C+ N+ F+C+C G+ D +R C A + L+F+ + I
Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDER-HCIAVQNF--LIFSSQVAI 719
Query: 449 RKI----SLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVV 504
R I S MV + + +D+ + IF+SD++ I+K ID GT R ++
Sbjct: 720 RGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKID-GTGREIL 778
Query: 505 IGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLE 564
++ + LA DW+ +LYWTD+ + I + L R+ +++ L PR++ ++P
Sbjct: 779 AANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQ-YLNNPRSVVVHPFA 837
Query: 565 GWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
G++F+TDW + KI RA DGSH +++ + WPNGL +D R+YWVDA + I
Sbjct: 838 GYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHS 897
Query: 625 NYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTL 684
+DG RR + H E + HPF + F + +++TDW A+ R K +G ++ I S
Sbjct: 898 TFDGLDRRRLGH-IEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIAY 956
Query: 685 QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQ 744
+ + + + N NG CSH C P P F RV C CP G++L +
Sbjct: 957 ILHLKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPNF----QRV-CGCPYGMRLASNHL 1011
Query: 745 MCVED 749
C D
Sbjct: 1012 TCEGD 1016
Score = 193 bits (470), Expect = 2e-48
Identities = 115/335 (34%), Positives = 155/335 (46%), Gaps = 28/335 (8%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C+S++F C +CIP+ WKCD +KDCSD SDE + + C+ +F+C SDG C
Sbjct: 3512 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE---LALCPQRFCRLGQFQC-SDGNCTS 3567
Query: 82 RSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
C+A +CPDGSDE + CE C E+ C K C+P +W CD DC D SDE
Sbjct: 3568 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANK--RCIPESWQCDTFNDCEDNSDE 3625
Query: 140 KA---CNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPT--CQPQSHFS 192
+ + TCR +F C NG+CI W E +C + C + FS
Sbjct: 3626 DSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 3685
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C T+ +CI W C+G DC D SDE GC + R+ +F C + C+ W
Sbjct: 3686 CKTNYRCIPKWAVCNGVDDCRDNSDEQGC----EERTCHPVGDFRCKNH-HCIPLRWQCD 3740
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK 311
E E C C +F+C + CIP C+ DC D SDE +C +
Sbjct: 3741 GQNDCGDNSDE--ENCAPR-ECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDC--EM 3795
Query: 312 TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
C F C G C+ CD DC + DE
Sbjct: 3796 RTCHPE-YFQCTSGHCVHSELKCDGSADCLDASDE 3829
Score = 180 bits (439), Expect = 1e-44
Identities = 111/359 (30%), Positives = 174/359 (48%), Gaps = 21/359 (5%)
Query: 400 GSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD--- 454
G CS +C G T KC+C G + D C A L+FA + +R + LD
Sbjct: 2351 GGCSHLCFALPGLHTPKCDCAFGTLQS--DGKNC-AISTENFLIFALSNSLRSLHLDPEN 2407
Query: 455 HHEMVAIVNDTKSATALDYVFRTGMIFWSD---VNDEKIYKAPIDEGTQRTVVIGEQLIT 511
H +N ++ +LDY + I+++ +I A + G VI + T
Sbjct: 2408 HSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGT 2467
Query: 512 SDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
+DG+A DW+ +Y++D + I G+ R ++ R + +PRAI L+P +G+++W D
Sbjct: 2468 ADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIAR--VPKPRAIVLDPCQGYLYWAD 2525
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
W KIERA + G+ R IV+ + P+GLTLD +YWVDA + I G R
Sbjct: 2526 WDTHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQRIERSTLTGVDR 2585
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+I+++ H F +T + ++YWTD +YRANK++G A+T T+ L P I+
Sbjct: 2586 EVIVNAAV---HAFGLTLYGQYIYWTDLYTQRIYRANKYDGSGQIAMT-TNLLSQPRGIN 2641
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
++ N C NG CSH+C P GPN C L + + C+ D+
Sbjct: 2642 TVVKNQKQQCNNPCEQFNGGCSHICAP----GPNGAECQCPHEGNWYLANNRKHCIVDN 2696
Score = 171 bits (416), Expect = 8e-42
Identities = 108/318 (33%), Positives = 145/318 (45%), Gaps = 23/318 (7%)
Query: 65 VCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGECVPL 123
+C +F C ++ CIP W+CD DC DGSDE C C +F C G C
Sbjct: 3511 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQC--SDGNCTSP 3568
Query: 124 TWMCDDNPDCSDGSDEK--AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--V 178
+C+ + +C DGSDE C N C S+E+ C N +CI W E
Sbjct: 3569 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSS 3628
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCIS-TEF 235
C + TC+P F C +G+CI W CD D DC D SDE C+S+ + C + TEF
Sbjct: 3629 HCASRTCRP-GQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHL---CDNFTEF 3684
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C C+ + V E + C + F+CK+H CIP C+G
Sbjct: 3685 SCKTNYRCIPKWAVCNGVDDCRDNSDE--QGCEERTCHPVGDFRCKNHHCIPLRWQCDGQ 3742
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE 355
DC D SDE NC ++ C + +EF C CIP +CD + DC + DE RD C
Sbjct: 3743 NDCGDNSDEENCAPRE--CTE-SEFRCVNQQCIPSRWICDHYNDCGDNSDE-RD-CEMRT 3797
Query: 356 CEKNNGGC-SQRCVDTPI 372
C C S CV + +
Sbjct: 3798 CHPEYFQCTSGHCVHSEL 3815
Score = 156 bits (378), Expect = 3e-37
Identities = 118/409 (28%), Positives = 200/409 (48%), Gaps = 36/409 (8%)
Query: 380 KGYKLIDNRTC-EDIDECADP-GSCSQICINEKG-TFKCECHTGYARDPRDRTRCKATEG 436
+G ++ R E + C++ +C QIC+ G F C C TG+ +P +R+ C
Sbjct: 2005 RGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRS-CSPYNS 2063
Query: 437 HPSLLFARKHDIRKISL---DHHE-MVAIVNDTKSATALDYVFRTGMIFWSD-----VND 487
++ + IR SL DH E MV + ++A +D +G I+W D +D
Sbjct: 2064 F--IVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASD 2121
Query: 488 EKIYKAPIDEGTQRTVV---IGEQLITSDGLAVDWVYNHLYWTDT--GHNHIELSDLQGN 542
I + D + +V IGE + G+AVDWV +LY+T+ IE+ +
Sbjct: 2122 NAIRRIKPDGSSLMNIVTHGIGENGVR--GIAVDWVAGNLYFTNAFVSETLIEVLRINTT 2179
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGL 602
R++L++ ++ PR I ++P ++FW D+GQ PKIER+ +D ++R+ +VS + P GL
Sbjct: 2180 YRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGL 2239
Query: 603 TLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKT 662
+D VYWVD ++ I+ +G +I + + P+ IT FE+ + W D +
Sbjct: 2240 AVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSR-YPTPYGITVFENSIIWVDRNLK 2298
Query: 663 AVYRANKFNGKDVEAIT----STHTLQNPMVIHVYHPYRQPDGVNH--CAAVNGHCSHLC 716
+++A+K ++ E T + + L++ + R P VN+ C NG CSHLC
Sbjct: 2299 KIFQASK-EPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLENNGGCSHLC 2357
Query: 717 LPAPRFGPNSPRVSCACPNGLKLLPDDQMC-VEDSKYHFLPFYNNFRSI 764
P G ++P+ C C G L D + C + + N+ RS+
Sbjct: 2358 FALP--GLHTPK--CDCAFG-TLQSDGKNCAISTENFLIFALSNSLRSL 2401
Score = 146 bits (354), Expect = 3e-34
Identities = 81/207 (39%), Positives = 102/207 (49%), Gaps = 13/207 (6%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + TC S+F C RCI LS+ CD +KDC D SDE V + C +F+C S
Sbjct: 1144 NSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCV-----LNCTASQFKCASGD 1198
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVE---ACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
CI + RCD DC D SDE C C +EF C+ + G C+P W CD +PDC
Sbjct: 1199 KCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQ-EDGICIPNFWECDGHPDCL 1257
Query: 135 DGSDE-KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHF 191
GSDE AC +TC S F C NG CI W+ E CPT P P +
Sbjct: 1258 YGSDEHNACVPKTCPSSYFHCDNGNCIHRXWLCDRDNDCGDMSDEKDCPTQPFRCPSWQW 1317
Query: 192 SCTDGQ-CISAWWHCDGDVDCADGSDE 217
C C++ CDG DC +G+DE
Sbjct: 1318 QCLGHNICVNLSVVCDGIFDCPNGTDE 1344
Score = 141 bits (342), Expect = 7e-33
Identities = 111/373 (29%), Positives = 175/373 (46%), Gaps = 34/373 (9%)
Query: 393 IDECADPGSCSQICI-NEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIR 449
++ CA CS +C+ + +G + C C +G++ P D C + P L+ R+H I
Sbjct: 1701 VNPCAF-SRCSHLCLLSSQGPHFYSCVCPSGWSLSP-DLLNC-LRDDQPFLITVRQHIIF 1757
Query: 450 KISLDHHEMV--AIVNDTKSATALDYVFRTG--MIFWSDVNDEKIYKAPIDEGTQRTVVI 505
ISL+ A+V LD F I+W + N +I++ D GT RTV
Sbjct: 1758 GISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVE-NPGEIHRVKTD-GTNRTVFA 1815
Query: 506 GEQLI-TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMR--KILIRDR-----LEEPRA 557
++ S LA+DW+ +LY T+ IE+ L G++R K LI + + P
Sbjct: 1816 SISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIG 1875
Query: 558 IALNPLEGWMFWTDWGQ---VP-KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
I ++P G ++W+D G VP KI A MDG+ T+ + +++ +TLD+ Q++YW
Sbjct: 1876 ITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQKLYW 1935
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
I N DG+ R +++H L HP+ I + ++Y+TD + R +K G
Sbjct: 1936 AVTGRGVIERGNVDGTDRMILVHQ---LSHPWGIAVHDSFLYYTDEQYEVIERVDKATG- 1991
Query: 674 DVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
I + N + VYH + N C+ C +CLP P SCAC
Sbjct: 1992 -ANKIVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVP-----GGLFSCAC 2045
Query: 734 PNGLKLLPDDQMC 746
G KL PD++ C
Sbjct: 2046 ATGFKLNPDNRSC 2058
Score = 130 bits (314), Expect = 2e-29
Identities = 88/276 (31%), Positives = 124/276 (44%), Gaps = 23/276 (8%)
Query: 144 ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQCISA 201
E C + FTC NG+CI W E++ C TC P + F+C +G+C+
Sbjct: 2698 ERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTA-FTCANGRCVQY 2756
Query: 202 WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXX 261
+ CD DC DGSDE GC+ R +TEF CN+R C+ R ++
Sbjct: 2757 SYRCDYYNDCGDGSDEAGCL----FRDCNATTEFMCNNR-RCIPREFICNGVDNCHDNNT 2811
Query: 262 EALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
+ C TC+ +C + + CIP C+G DC D SDE N T T +EF
Sbjct: 2812 SDEKNCPDR-TCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDE-NPTYCTTHTCSSSEF 2869
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGC-SQRCVDTPIGYYCD 377
C G CIP CD+ DC + DEP CG +E C + C RC+ P + CD
Sbjct: 2870 QCTSGRCIPQHWYCDQETDCFDASDEPAS-CGHSERTCLADEFKCDGGRCI--PSEWICD 2926
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQ---ICINEK 410
G + + ED +CS +C+N++
Sbjct: 2927 ---GDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDR 2959
Score = 124 bits (300), Expect = 9e-28
Identities = 76/249 (30%), Positives = 104/249 (41%), Gaps = 14/249 (5%)
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT--PTCQPQSH 190
C + E C F C NG+C+ ++ E C T TC S
Sbjct: 1013 CEGDPTNEPPTEQCGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCS-SSA 1071
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
F+C G+CI A W CD DC DGSDE C + + C+ T++ C D C+ + WV
Sbjct: 1072 FTCGHGECIPAHWRCDKRNDCVDGSDEHNCPT--HAPASCLDTQYTC-DNHQCISKNWVC 1128
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C TC+ QF C +H CI + C+G KDC DGSDE C
Sbjct: 1129 DTDNDCGDGSDE--KNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLN 1186
Query: 311 KTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQRCV 368
T ++F C G CI ++ CD DC + DE C + C + +
Sbjct: 1187 CT----ASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGI 1242
Query: 369 DTPIGYYCD 377
P + CD
Sbjct: 1243 CIPNFWECD 1251
Score = 117 bits (282), Expect = 1e-25
Identities = 100/339 (29%), Positives = 136/339 (40%), Gaps = 31/339 (9%)
Query: 113 CRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXX 171
C KPG T C D+ S C C S +F C N KCI + W
Sbjct: 3480 CLIKPGG-KGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDC 3538
Query: 172 XXXXXEVK-CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPC 230
E+ CP C+ F C+DG C S C+ +C DGSDE + C
Sbjct: 3539 SDGSDELALCPQRFCR-LGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCE---NHHC 3594
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGAL 290
S E++C ++ C+ +W E C TCR QF+C + CIP A
Sbjct: 3595 DSNEWQCANK-RCIPESWQCDTFNDCEDNSDEDSSHCASR-TCRPGQFRCANGRCIPQAW 3652
Query: 291 YCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEP 347
C+ DC D SDE C +CD TEF C CIP VC+ DC + DE
Sbjct: 3653 KCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE- 3711
Query: 348 RDRCGENECEK-NNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQI 405
C E C + C + C+ P+ + CD + DN D + CA P C++
Sbjct: 3712 -QGCEERTCHPVGDFRCKNHHCI--PLRWQCDGQNDCG--DN---SDEENCA-PRECTES 3762
Query: 406 ---CINEK---GTFKCECHTGYARDPRDRTRCKATEGHP 438
C+N++ + C+ H D D C+ HP
Sbjct: 3763 EFRCVNQQCIPSRWICD-HYNDCGDNSDERDCEMRTCHP 3800
Score = 64.1 bits (149), Expect = 2e-09
Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY-CDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEK 410
N C N C Q C+ P G + C C G+KL DNR+C + S I + +
Sbjct: 2020 NGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLE 2079
Query: 411 GTFKCECHTGYARDPRDRTRCKATEGHPSLLF-------ARKHDIRKISLDHHEMVAIV- 462
+ E A R+ + + A + IR+I D ++ IV
Sbjct: 2080 LSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVT 2139
Query: 463 ----NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ A+D+V + F + E + + T R V++ + + VD
Sbjct: 2140 HGIGENGVRGIAVDWV-AGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVD 2198
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+L+W D G IE S L R +L+ + + PR +A++ +G+++W D +
Sbjct: 2199 PKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVD-DSLDI 2257
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTI 621
I R ++G + S ++ Y ++P + + + WVD + I
Sbjct: 2258 IARIRINGEN-SEVIRYGSRYPTPYGITVFENSIIWVDRNLKKI 2300
Score = 39.9 bits (89), Expect = 0.033
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDC--EKGYKLIDNRTCEDIDECADPGSCSQI 405
+ +C N CE+ NGGCS C P G C C E + L +NR +D G+ S
Sbjct: 2648 KQQCN-NPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFT 2706
Query: 406 CIN 408
C N
Sbjct: 2707 CSN 2709
Score = 34.3 bits (75), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYY---CDCEKGYKLIDNRTC 390
N C +NNGGCS C P G + CDC G D + C
Sbjct: 2344 NPCLENNGGCSHLCFALP-GLHTPKCDCAFGTLQSDGKNC 2382
>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
(AA -19 to 4525) protein.
Length = 4544
Score = 526 bits (1297), Expect = e-148
Identities = 289/750 (38%), Positives = 396/750 (52%), Gaps = 44/750 (5%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCTAT-KMVCQEYRFE-CLSDG 77
C EFRC+ G CI S +C+ DC D+SDE T C++ ++ + F+ C
Sbjct: 2605 CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTS 2664
Query: 78 LCIPRSWRCDATADCPDGSDEHQC---EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
LC SW CD DC D SDE C + C F C G C+P++W CD DC
Sbjct: 2665 LCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPS--GRCIPMSWTCDKEDDCE 2722
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK-CPTPTCQPQSHFSC 193
G DE CN+ C +F C N +CI +W+ E C TC P S FSC
Sbjct: 2723 HGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS-FSC 2781
Query: 194 TDGQ-CISAWWHCDGDVDCADGSDE---VGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
C+ W CDGD DCADG+DE GC+ S C EF C +R C+ + +V
Sbjct: 2782 PGTHVCVPERWLCDGDKDCADGADESIAAGCL----YNSTCDDREFMCQNR-QCIPKHFV 2836
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY--- 305
E+ E C TC +F+C + C+ + C+G DC D SDE
Sbjct: 2837 CDHDRDCADGSDESPE-CE-YPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKN 2894
Query: 306 -NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGC 363
+CT + C+ ++F C G C+ + +C+ DC + DE C NEC + GC
Sbjct: 2895 PHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERG--CHINECLSRKLSGC 2952
Query: 364 SQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYA 422
SQ C D IG+ C C G++L D+ RTC D+DEC+ CSQ CIN G++KC C GYA
Sbjct: 2953 SQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYA 3012
Query: 423 RDPRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIF 481
D CKA T+ P L+FA ++ +RK++LD + +A ALD+ +R MI+
Sbjct: 3013 PRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIY 3072
Query: 482 WSDVNDE-KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
W+DV + + + G+ V+ L DGLAVDWV +LYW D G + IE+S L
Sbjct: 3073 WTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLN 3132
Query: 541 GNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPN 600
G R +L+ L EPRA+ ++ G+++WTDWG I R GMDGS RS IV + WPN
Sbjct: 3133 GAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPN 3192
Query: 601 GLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD 660
GLTLD V +R+YW DA+ + I + DGS R ++L ++ + H F++T FED+VYWTDW+
Sbjct: 3193 GLTLDYVTERIYWADAREDYIEFASLDGSNRHVVL--SQDIPHIFALTLFEDYVYWTDWE 3250
Query: 661 KTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPA 719
++ RA+K G + + S TL PM +HV+H RQPD NH C NG CS+LCL +
Sbjct: 3251 TKSINRAHKTTGTNKTLLIS--TLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLS 3308
Query: 720 PRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
P G CACP L D + CV +
Sbjct: 3309 PGGGH-----KCACPTNFYLGSDGRTCVSN 3333
Score = 516 bits (1274), Expect = e-146
Identities = 284/755 (37%), Positives = 393/755 (52%), Gaps = 49/755 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C EF C RCI WKCD + DC D+SDE P +C + C RF+C + CIP
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCH--QHTCPSDRFKC-ENNRCIPN 910
Query: 83 SWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD DC + DE C C P +F+C G C+P++W CD + DC D SDE
Sbjct: 911 RWLCDGDNDCGNSEDESNATCSARTCPPNQFSCAS--GRCIPISWTCDLDDDCGDRSDES 968
Query: 141 A--CNETCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
A TC +FTC NG+CI + W E C + +C + F C G+
Sbjct: 969 ASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGC-SHSCS-STQFKCNSGR 1026
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECNDRITCVHRAWVXXXXX 254
CI W CDGD DC D SDE T + P C + EF+C C+ W
Sbjct: 1027 CIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDT 1086
Query: 255 XXXXXXXEALELCRGNVTCRLD---QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C G VT D +F CKD + CI A C+G DC D SDE NC
Sbjct: 1087 DCMDSSDE--KSCEG-VTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENC--- 1140
Query: 311 KTICDKRTEFDCGGG--MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCV 368
+++ + C +C+P K+CD + DC + DE + C ++C NNGGCS C
Sbjct: 1141 ESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEG-ELC--DQCSLNNGGCSHNCS 1197
Query: 369 DTP-IGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
P G C C G +L DN TC+ CA CSQ C K + KC C+ G+ +P
Sbjct: 1198 VAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEP- 1256
Query: 427 DRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDV 485
D C++ + P ++F+ +H+IR+I L + +V ++ ALD+ ++W+DV
Sbjct: 1257 DGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDV 1316
Query: 486 NDEKIYKAPI-DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGN 542
++KIY+ + D G T VVI L T +GLAVDW+ ++YW ++ + IE++ L G
Sbjct: 1317 VEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGT 1376
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDW-GQVPKIERAGMDGSHRSTI--VSYDVKWP 599
+R L+ +E PRAIAL+P +G +FWTDW +P+IE A M G+ R T+ + WP
Sbjct: 1377 LRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWP 1436
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDW 659
NGLT+D + +R+ W+DA+ + I S YDGSG +L E L HPF++T + VYWTDW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 660 DKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLCL 717
+ +ANK+ G +V + T+T P + VYHP RQP N C A G CSHLCL
Sbjct: 1497 RTNTLAKANKWTGHNVTVVQRTNT--QPFDLQVYHPSRQPMAPNPCEANGGQGPCSHLCL 1554
Query: 718 PAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
N VSCACP+ +KL D+ C E K+
Sbjct: 1555 ----INYNR-TVSCACPHLMKLHKDNTTCYEFKKF 1584
Score = 461 bits (1136), Expect = e-129
Identities = 267/760 (35%), Positives = 370/760 (48%), Gaps = 62/760 (8%)
Query: 22 TCTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
TC ++F+C T RCIP W CD + DC D SDE P CT +M C F C G CI
Sbjct: 3452 TCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCT--QMTCGVDEFRCKDSGRCI 3508
Query: 81 PRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
P W+CD DC DGSDE +C+ C P +F C K CVP W CD + DC D SD
Sbjct: 3509 PARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRC--KNNRCVPGRWQCDYDNDCGDNSD 3566
Query: 139 EKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
E++C C EF+C NG+CI RW E C TP C F C G
Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-TPRCD-MDQFQCKSGH 3624
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
CI W CD D DC DGSDE C + VR+ C EF+CN+ + C AW
Sbjct: 3625 CIPLRWRCDADADCMDGSDEEACGT--GVRT-CPLDEFQCNNTL-CKPLAWKCDGEDDCG 3680
Query: 258 XXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNC---TRQKTI 313
E E C V F+CK D C+ C+G +C DG+DE +C T T
Sbjct: 3681 DNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 3740
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQ--RCVD 369
C + EF C C+ S C+ DC + DE C N C RCV
Sbjct: 3741 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Query: 370 TPIGYYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
T YC C G+ + + C+DI+EC G+CSQ+C N KG C C + +
Sbjct: 3801 TEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFM---KTH 3857
Query: 429 TRCKATEGHPSLLF-ARKHDIRKISLDH----HEMVAIVNDTKSATALDYVFRTGMIFWS 483
CKA +L+ A ++IR + H +E +++ A+D + G ++W+
Sbjct: 3858 NTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT 3917
Query: 484 DVNDEKI----------------YKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWT 527
+ + I ++ ID G + G L G+A+DWV ++YWT
Sbjct: 3918 NWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISG--LKMPRGIAIDWVAGNVYWT 3975
Query: 528 DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSH 587
D+G + IE++ ++G RK LI ++EP AI ++PL G M+W+DWG PKIE A MDG+
Sbjct: 3976 DSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTL 4035
Query: 588 RSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSI 647
R T+V +++WP GL +D +R+YW DAK++ I S +G+ + S L HPFSI
Sbjct: 4036 RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSI 4095
Query: 648 TTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAA 707
FED++Y + V++ +KF + + T L + + +YH ++QP+ N C
Sbjct: 4096 DVFEDYIYGVTYINNRVFKIHKFGHSPL--VNLTGGLSHASDVVLYHQHKQPEVTNPCD- 4152
Query: 708 VNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C LCL +P GP C CPNG +L D+ CV
Sbjct: 4153 -RKKCEWLCLLSPS-GP-----VCTCPNGKRL--DNGTCV 4183
Score = 280 bits (686), Expect = 2e-74
Identities = 171/516 (33%), Positives = 267/516 (51%), Gaps = 41/516 (7%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVNDE------KIYKAPI 495
A +I L ++ I T+ TA+D+ + + W V D K + P
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPG 263
Query: 496 DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLE 553
+G + T+ I L + +A+DW+ + Y+ D + I + + G+ L+ L
Sbjct: 264 LKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELY 323
Query: 554 EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
P+ IAL+P G +F+TD+GQ+PK+ER MDG +R+ +V + +P+G+TLDLV + VYW
Sbjct: 324 NPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYW 383
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD------KTAVYRA 667
DA ++ I +Y+G GR+ I+ ++ H + +T FE+++Y T+ D KT+V R
Sbjct: 384 ADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV 442
Query: 668 NKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRF 722
N+FN + + +T + +H+YH RQP +H + G CS +CL A
Sbjct: 443 NRFNSTEYQVVT---RVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLA--- 496
Query: 723 GPNSPRV-SCACPNGLKLLPDDQMCVEDSKYHFLPF 757
NS + +C C +G L D + C + FL +
Sbjct: 497 --NSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVY 530
Score = 249 bits (609), Expect = 3e-65
Identities = 189/637 (29%), Positives = 272/637 (42%), Gaps = 58/637 (9%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC S F+C+ RCIP W CD + DC +S DE C+A C +F C S G CIP
Sbjct: 894 TCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSA--RTCPPNQFSCAS-GRCIP 950
Query: 82 RSWRCDATADCPDGSDEH-QCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
SW CD DC D SDE C C P +FTC G C+ + W CD++ DC D SDE
Sbjct: 951 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNN--GRCININWRCDNDNDCGDNSDE 1008
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPTCQP-----QSHFS 192
C+ +C S +F C +G+CI W E C +P F
Sbjct: 1009 AGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQ 1068
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C DG CI W CDGD DC D SDE C V P S +F C D C+ +AWV
Sbjct: 1069 CRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP--SVKFGCKDSARCISKAWVCD 1126
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTR 309
E E C ++ CR C +++ C+P C+G DC DGSDE
Sbjct: 1127 GDNDCEDNSDE--ENCE-SLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCD 1183
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDR-CG-ENECEKNNGGCSQR 366
Q ++ + +C + VC CP E P + C ++ C K+ CSQ+
Sbjct: 1184 QCSLNNGGCSHNC--SVAPGEGIVC----SCPLGMELGPDNHTCQIQSYCAKHL-KCSQK 1236
Query: 367 CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG-YARD 424
C C C +G+ L D +C + DP I N + + H G Y+
Sbjct: 1237 CDQNKFSVKCSCYEGWVLEPDGESCRSL----DPFKPFIIFSNRHEIRRIDLHKGDYSVL 1292
Query: 425 PRDRTRCKATEGHPSLLFARKHDI------RKISLDHHEMVA---IVN---DTKSATALD 472
A + H S D+ R LD+ + + ++ T A+D
Sbjct: 1293 VPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVD 1352
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
++ G I+W + N ++I A +D GT RT ++ + +A+D L+WTD +
Sbjct: 1353 WI--AGNIYWVESNLDQIEVAKLD-GTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDAS 1409
Query: 533 --HIELSDLQGNMRKILIRDRLEE--PRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
IE + + G R+ + R+ P + ++ LE + W D + I A DGS
Sbjct: 1410 LPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWID-ARSDAIYSARYDGSGH 1468
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
++ + + L VYW D + NT++ N
Sbjct: 1469 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKAN 1505
Score = 229 bits (561), Expect = 2e-59
Identities = 139/392 (35%), Positives = 182/392 (46%), Gaps = 29/392 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L S+ RTC T+S+F CK +CIP WKCD E DC D SDE P C K C+
Sbjct: 3321 FYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPD-CPEFK--CRPG 3377
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
+F+C S G+C ++ CD DC D SDE C++ C P +F C C+P + C+
Sbjct: 3378 QFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT-NTNRCIPGIFRCNG 3435
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQ 186
+C DG DE+ C E TC ++F C +CI WV E C TC
Sbjct: 3436 QDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC- 3494
Query: 187 PQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D G+CI A W CDG+ DC DGSDE + C +F C + CV
Sbjct: 3495 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERT---CEPYQFRCKNN-RCVP 3550
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
W E E C C +F C + CI G C+G DC DGSDE
Sbjct: 3551 GRWQCDYDNDCGDNSDE--ESCTPR-PCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 3607
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+CT + CD +F C G CIPL CD DC + DE G C + C+
Sbjct: 3608 DCTPR---CD-MDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN- 3662
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
+ P+ + CD E + + E+ +ECA
Sbjct: 3663 NTLCKPLAWKCDGEDD---CGDNSDENPEECA 3691
Score = 209 bits (511), Expect = 2e-53
Identities = 132/388 (34%), Positives = 199/388 (51%), Gaps = 32/388 (8%)
Query: 385 IDNRTCEDIDECADPGSCSQICI--NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
+ + CE+ D+ PG CS IC+ N C C +G++ D CK E L++
Sbjct: 473 VRSHACEN-DQYGKPGGCSDICLLANSHKARTCRCRSGFSLGS-DGKSCKKPEHELFLVY 530
Query: 443 ARKHD--IRKISL-----DHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
+ IR + + D H M+ I N + ALD+ TG I+++D I + I
Sbjct: 531 GKGRPGIIRGMDMGAKVPDEH-MIPIEN-LMNPRALDFHAETGFIYFADTTSYLIGRQKI 588
Query: 496 DEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDRL 552
D GT+R ++ + + +G+AVDW+ ++LYWTD G I ++ L+ RK LI ++
Sbjct: 589 D-GTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKM 647
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPK------IERAGMDGSHRSTIV-SYDVKWPNGLTLD 605
PRAI ++PL GWM+WTDW + PK +ERA MDGSHR V S V WPNGL+LD
Sbjct: 648 THPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLD 707
Query: 606 LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVY 665
+ R+YWVDA + I + +G+ R+++ E L H F + ++++WT++ +VY
Sbjct: 708 IPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPE-LNHAFGLCHHGNYLFWTEYRSGSVY 766
Query: 666 RANKFNGKDVEAITSTHTLQNPMV-IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGP 724
R + G +T + + P+ I +Y +Q G N C NG CS LCL P G
Sbjct: 767 RLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATP--GS 824
Query: 725 NSPRVSCACPNGLKLLPDDQMCVEDSKY 752
CAC L D C+ + Y
Sbjct: 825 R----QCACAEDQVLDADGVTCLANPSY 848
Score = 207 bits (506), Expect = 1e-52
Identities = 123/361 (34%), Positives = 198/361 (54%), Gaps = 23/361 (6%)
Query: 400 GSCSQICI-NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHD-IRKISLDHHE 457
G CSQ+C+ + T C C GY+ R+ +A EG S L H+ IR I LD ++
Sbjct: 1855 GDCSQLCLPTSETTRSCMCTAGYSL----RSGQQACEGVGSFLLYSVHEGIRGIPLDPND 1910
Query: 458 M---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ V+ T A +D+ I+W D+ I +A D+ T R V+ + +G
Sbjct: 1911 KSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQ-TWREDVVTNGIGRVEG 1969
Query: 515 LAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ 574
+AVDW+ ++YWTD G + IE++ L G+ R ++I L++PRAI ++P +G++FWT+WGQ
Sbjct: 1970 IAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQ 2029
Query: 575 VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYD-GSGRRL 633
P+IER+ +DG+ R +V+ + WPNG+++D ++YW DA+ + I + + G R +
Sbjct: 2030 YPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREV 2089
Query: 634 ILHSTEVLRHPFSITTFEDWVYWTDWDKT--AVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+L S + FS++ FED++YW+D ++ R +K N D + + +Q I
Sbjct: 2090 VLSSNNM--DMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQ-LKDIK 2146
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
V++ RQ G N CA NG C LCL R + +CAC +G+ L D C E +
Sbjct: 2147 VFNRDRQ-KGTNVCAVANGGCQQLCLYRGR-----GQRACACAHGM-LAEDGASCREYAG 2199
Query: 752 Y 752
Y
Sbjct: 2200 Y 2200
Score = 195 bits (476), Expect = 4e-49
Identities = 124/359 (34%), Positives = 153/359 (42%), Gaps = 39/359 (10%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
EF C G CI S CD C D SDE P+ C + + C++ +C S+G C+ C
Sbjct: 2529 EFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRR--CKKTFRQC-SNGRCVSNMLWC 2585
Query: 87 DATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
+ DC DGSDE C ACG EF CR G C+ + C+ DC D SDE C+ T
Sbjct: 2586 NGADDCGDGSDEIPCNKTACGVGEFRCR--DGTCIGNSSRCNQFVDCEDASDEMNCSATD 2643
Query: 147 RSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCP---TPTCQPQSHFS 192
S F G C WV E CP P C P ++F+
Sbjct: 2644 CSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC-PLNYFA 2702
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CD + DC G DE C C +FEC + C+ + W+
Sbjct: 2703 CPSGRCIPMSWTCDKEDDCEHGEDETHC------NKFCSEAQFECQNH-RCISKQWLCDG 2755
Query: 253 XXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDE---YNCT 308
EA C G TC F C H C+P C+G KDC DG+DE C
Sbjct: 2756 SDDCGDGSDEAAH-CEGK-TCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCL 2813
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD----RCGENECEKNNGGC 363
T CD R EF C CIP VCD DC + DE + CG +E NG C
Sbjct: 2814 YNST-CDDR-EFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRC 2870
Score = 176 bits (429), Expect = 2e-43
Identities = 116/372 (31%), Positives = 178/372 (47%), Gaps = 21/372 (5%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---H 455
G CS +C IN T C C + +D T C E LL+AR+ +IR + LD +
Sbjct: 1547 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCY--EFKKFLLYARQMEIRGVDLDAPYY 1603
Query: 456 HEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ +++ V D + T LDY R ++WSDV + I +A I+ GT V+ L + G
Sbjct: 1604 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFIN-GTGVETVVSADLPNAHG 1662
Query: 515 LAVDWVYNHLYWT--DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +L+WT DT I ++ L G+ + +++ LE+P + ++PL G ++WTD
Sbjct: 1663 LAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG-LEQPHGLVVHPLRGKLYWTDG 1721
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+R+ + S K P GL +D ++YW+ + +TI+ CN DGSG
Sbjct: 1722 DN---ISMANMDGSNRTLLFSGQ-KGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLE 1777
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I L ++ D ++W D + +K +G + ++ TL M ++
Sbjct: 1778 VIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYD 1837
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
G N C+ NG CS LCLP + SC C G L Q C +
Sbjct: 1838 ESIQLDHKGTNPCSVNNGDCSQLCLPT-----SETTRSCMCTAGYSLRSGQQACEGVGSF 1892
Query: 753 HFLPFYNNFRSI 764
+ R I
Sbjct: 1893 LLYSVHEGIRGI 1904
Score = 167 bits (405), Expect = 2e-40
Identities = 88/216 (40%), Positives = 107/216 (49%), Gaps = 19/216 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+RTC ++F C +GRCIP+SW CD + DC D SDE + T + F C ++G C
Sbjct: 933 ARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQ--FTC-NNGRC 989
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
I +WRCD DC D SDE C +C +F C G C+P W CD + DC D SDE
Sbjct: 990 ININWRCDNDNDCGDNSDEAGCS-HSCSSTQFKCNS--GRCIPEHWTCDGDNDCGDYSDE 1046
Query: 140 KACNET---------CRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP--TPTCQP 187
N T C +DEF C +G CI +RW E C T C P
Sbjct: 1047 THANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP 1106
Query: 188 QSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVS 222
F C D +CIS W CDGD DC D SDE C S
Sbjct: 1107 SVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCES 1142
Score = 153 bits (371), Expect = 2e-36
Identities = 110/369 (29%), Positives = 178/369 (48%), Gaps = 37/369 (10%)
Query: 400 GSCSQICINE-KGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISL-DHHE 457
G C Q+C+ +G C C G + D C+ G+ LL++ + ++ I L D
Sbjct: 2164 GGCQQLCLYRGRGQRACACAHGMLAE--DGASCREYAGY--LLYSERTILKSIHLSDERN 2219
Query: 458 MVAIVND------TKSATALDYVFRTGM-------IFWSDVNDEKIYKAPIDEGTQRTVV 504
+ A V K+ AL + +R G IF+SD++ I + D+G++R +
Sbjct: 2220 LNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQIN-DDGSRRITI 2278
Query: 505 IGEQLITSDGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEPRAI 558
+ E + + +GLA ++ LYWT T H + ++ + PRA
Sbjct: 2279 V-ENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAF 2337
Query: 559 ALNPLEGWMFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
L+ + MFWT+W Q P I RA + G++ T++ D++ PNGL +D +++Y+ DA
Sbjct: 2338 VLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDAT 2397
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ I C YDGS R +IL S V HPF + + + ++WTDW + AV RANK G +++
Sbjct: 2398 LDKIERCEYDGSHRYVILKSEPV--HPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMK- 2454
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ Q PM I ++ C NG C LCL + V+C+C G
Sbjct: 2455 LLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLT-----HQGHVNCSCRGG- 2508
Query: 738 KLLPDDQMC 746
++L DD C
Sbjct: 2509 RILQDDLTC 2517
Score = 147 bits (356), Expect = 1e-34
Identities = 75/214 (35%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C+ ++F C+ RCI W CD DC D SDE C F C +C
Sbjct: 2731 NKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSSFSCPGTHVC 2787
Query: 80 IPRSWRCDATADCPDGSDEH---QCEVEA-CGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+P W CD DC DG+DE C + C EF C+ + +C+P ++CD + DC+D
Sbjct: 2788 VPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNR--QCIPKHFVCDHDRDCAD 2845
Query: 136 GSDEK-ACN-ETCRSDEFTCGNGKCIQMR-WVXXXXXXXXXXXXEV----KCPTP--TCQ 186
GSDE C TC EF C NG+C+ R W E C +P C
Sbjct: 2846 GSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCN 2905
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C+ G+C++ C+G DC D SDE GC
Sbjct: 2906 ASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 2939
Score = 138 bits (333), Expect = 9e-32
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 9/148 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCT--ATKMV--CQEYRFECLS 75
S +C+S++F+C +GRCIP W CD + DC D SDE CT AT+ C F+C
Sbjct: 1012 SHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRL 1071
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCE--VEACGPE-EFTCRGKPGECVPLTWMCDDNPD 132
DGLCIP WRCD DC D SDE CE C P +F C+ C+ W+CD + D
Sbjct: 1072 DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDS-ARCISKAWVCDGDND 1130
Query: 133 CSDGSDEKACNE-TCRSDEFTCGNGKCI 159
C D SDE+ C CR C N +
Sbjct: 1131 CEDNSDEENCESLACRPPSHPCANNTSV 1158
Score = 133 bits (322), Expect = 2e-30
Identities = 115/385 (29%), Positives = 147/385 (38%), Gaps = 37/385 (9%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKC-DNEKDCSDSSD---EDPTVCTATKMVCQ-EYRFE 72
+++ +C S R G C L +CS +D C A C+ + FE
Sbjct: 2472 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFE 2531
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C ++G CI S CD C D SDE C C C G CV C+
Sbjct: 2532 C-ANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSN--GRCVSNMLWCNGA 2588
Query: 131 PDCSDGSDEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC DGSDE CN+T C EF C +G CI E+ C C
Sbjct: 2589 DDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYF 2648
Query: 190 HFS--------C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP-CISTEFECND 239
C C + W CDG DC D SDE C P V+ P C F C
Sbjct: 2649 RLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDC---PGVKRPRCPLNYFACPS 2705
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
C+ +W E N C QF+C++H CI C+G DC
Sbjct: 2706 G-RCIPMSWTCDKEDDCEHGEDET----HCNKFCSEAQFECQNHRCISKQWLCDGSDDCG 2760
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-C 356
DGSDE KT C + F C G +C+P +CD DC + DE C N C
Sbjct: 2761 DGSDEAAHCEGKT-CGP-SSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTC 2818
Query: 357 EKNNGGCSQR-CVDTPIGYYCDCEK 380
+ C R C+ P + CD ++
Sbjct: 2819 DDREFMCQNRQCI--PKHFVCDHDR 2841
Score = 111 bits (267), Expect = 9e-24
Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 17/153 (11%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLC 79
RTC EF+C C PL+WKCD E DC D+SDE+P C + VC R F C +D +C
Sbjct: 3652 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC--ARFVCPPNRPFRCKNDRVC 3709
Query: 80 IPRSWRCDATADCPDGSDEHQCE------VEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
+ +CD T +C DG+DE CE +EF CR + C+ + C+ DC
Sbjct: 3710 LWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ--RCLSSSLRCNMFDDC 3767
Query: 134 SDGSDEKACN-----ETCRSDEFTCGN-GKCIQ 160
DGSDE+ C+ +C ++ CG+ +C++
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Score = 92.3 bits (219), Expect = 6e-18
Identities = 51/150 (34%), Positives = 71/150 (47%), Gaps = 15/150 (10%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI- 80
TC EF C+ +CIP + CD+++DC+D SDE P T C F C ++G C+
Sbjct: 2817 TCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPT---CGPSEFRC-ANGRCLS 2872
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPE-------EFTCRGKPGECVPLTWMCDDNPDC 133
R W CD DC D SDE PE +F C G CV +C+ DC
Sbjct: 2873 SRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLC--SSGRCVAEALLCNGQDDC 2930
Query: 134 SDGSDEKACN-ETCRSDEFTCGNGKCIQMR 162
D SDE+ C+ C S + + + C ++
Sbjct: 2931 GDSSDERGCHINECLSRKLSGCSQDCEDLK 2960
Score = 91.1 bits (216), Expect = 1e-17
Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 37/397 (9%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECADPGSCSQICINEK--GTFKCECHT----------------GYARDPRDRTRCKATEG 436
E D I ++ T+ YA + +
Sbjct: 193 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAA 252
Query: 437 HPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
L AR ++ +H +++ A+D++ TG ++ D D++I+
Sbjct: 253 QTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWL--TGNFYFVDDIDDRIFVCN-R 309
Query: 497 EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEP 555
G ++ +L G+A+D +++TD G +E D+ G R L+ ++ P
Sbjct: 310 NGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFP 369
Query: 556 RAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I L+ + ++W D + IE +G R TI+
Sbjct: 370 HGITLDLVSRLVYWAD-AYLDYIEVVDYEGKGRQTII 405
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 85.4 bits (202), Expect = 7e-16
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 25/241 (10%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C+ Q F C +G+CI+ CDG C D SDE + C T +C++
Sbjct: 2523 SCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSR---RCKKTFRQCSNGRCV 2579
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ W E+ C + +F+C+D +CI + CN DC D SD
Sbjct: 2580 SNMLWCNGADDCGDGSD----EIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASD 2635
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC--PNFEDEPRDRCGENECEKNNG 361
E NC+ T C G + P C++ C P++ + + CG+ E++
Sbjct: 2636 EMNCS--ATDCSSYFRLGVKGVLFQP----CERTSLCYAPSWVCDGANDCGDYSDERDCP 2689
Query: 362 GCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC---ADPGSCSQICINEKGTFKCEC 417
G + RC P+ Y+ C G + + TC+ D+C D C++ C + F+C+
Sbjct: 2690 GVKRPRC---PLNYFA-CPSGRCIPMSWTCDKEDDCEHGEDETHCNKFC--SEAQFECQN 2743
Query: 418 H 418
H
Sbjct: 2744 H 2744
Score = 65.7 bits (153), Expect = 6e-10
Identities = 72/286 (25%), Positives = 118/286 (41%), Gaps = 35/286 (12%)
Query: 349 DRCGENECEKNNGGCSQRCVDT-PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICI 407
D G N C NNG CSQ C+ T C C GY L + C GS +
Sbjct: 1843 DHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQ-----QACEGVGSFLLYSV 1897
Query: 408 NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLL----FARKHD--------IRKISLDH 455
+E G G DP D++ SL F ++D + IS
Sbjct: 1898 HE-GI------RGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAK 1950
Query: 456 HEMV----AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLIT 511
+ + N + + G I+W+D + I A ++ G+ R VVI + L
Sbjct: 1951 RDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLN-GSFRYVVISQGLDK 2009
Query: 512 SDGLAVDWVYNHLYWTDTG-HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
+ V +L+WT+ G + IE S L G R +L+ + P I+++ +G ++W
Sbjct: 2010 PRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWC 2069
Query: 571 DWGQVPKIERAGMD-GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVD 615
D + KIER ++ G +R ++S + + ++ + +YW D
Sbjct: 2070 D-ARTDKIERIDLETGENREVVLSSNNM--DMFSVSVFEDFIYWSD 2112
Score = 53.6 bits (123), Expect = 3e-06
Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMCIP 329
CR++ C+D + + N C G D+ C + C + EF+C G CI
Sbjct: 2482 CRINNGGCQDLCLLTHQGHVNC--SCRGGRILQDDLTCRAVNSSCRAQDEFECANGECIN 2539
Query: 330 LSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKL 384
S CD C + DE C C+K CS RCV + +C DC G
Sbjct: 2540 FSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNML--WCNGADDCGDGSDE 2597
Query: 385 ID-NRTCEDIDE--CADPGSC 402
I N+T + E C D G+C
Sbjct: 2598 IPCNKTACGVGEFRCRD-GTC 2617
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 42.3 bits (95), Expect = 0.006
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 345 DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSC 402
D + + G N+C NNGGCS C+ TP C C + L D TC P C
Sbjct: 796 DAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQC 854
Score = 41.5 bits (93), Expect = 0.011
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
E + SS+F C +GRC+ + C+ + DC DSSDE
Sbjct: 2901 EHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDE 2936
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 16/91 (17%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDI------DECADPGSCSQICI 407
N C++ C C+ +P G C C G K +DN TC + + PG+C+ C
Sbjct: 4149 NPCDRKK--CEWLCLLSPSGPVCTCPNG-KRLDNGTCVPVPSPTPPPDAPRPGTCNLQCF 4205
Query: 408 NEKGTF-------KCECHTGYARDPRDRTRC 431
N F KC C Y D + +C
Sbjct: 4206 NGGSCFLNARRQPKCRCQPRYTGDKCELDQC 4236
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
lipoprotein-related protein 1 (alpha-2-macroglobulin
receptor) protein.
Length = 4544
Score = 526 bits (1297), Expect = e-148
Identities = 289/750 (38%), Positives = 396/750 (52%), Gaps = 44/750 (5%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCTAT-KMVCQEYRFE-CLSDG 77
C EFRC+ G CI S +C+ DC D+SDE T C++ ++ + F+ C
Sbjct: 2605 CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTS 2664
Query: 78 LCIPRSWRCDATADCPDGSDEHQC---EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
LC SW CD DC D SDE C + C F C G C+P++W CD DC
Sbjct: 2665 LCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPS--GRCIPMSWTCDKEDDCE 2722
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK-CPTPTCQPQSHFSC 193
G DE CN+ C +F C N +CI +W+ E C TC P S FSC
Sbjct: 2723 HGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS-FSC 2781
Query: 194 TDGQ-CISAWWHCDGDVDCADGSDE---VGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
C+ W CDGD DCADG+DE GC+ S C EF C +R C+ + +V
Sbjct: 2782 PGTHVCVPERWLCDGDKDCADGADESIAAGCL----YNSTCDDREFMCQNR-QCIPKHFV 2836
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY--- 305
E+ E C TC +F+C + C+ + C+G DC D SDE
Sbjct: 2837 CDHDRDCADGSDESPE-CE-YPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKN 2894
Query: 306 -NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGC 363
+CT + C+ ++F C G C+ + +C+ DC + DE C NEC + GC
Sbjct: 2895 PHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERG--CHINECLSRKLSGC 2952
Query: 364 SQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYA 422
SQ C D IG+ C C G++L D+ RTC D+DEC+ CSQ CIN G++KC C GYA
Sbjct: 2953 SQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYA 3012
Query: 423 RDPRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIF 481
D CKA T+ P L+FA ++ +RK++LD + +A ALD+ +R MI+
Sbjct: 3013 PRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIY 3072
Query: 482 WSDVNDE-KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
W+DV + + + G+ V+ L DGLAVDWV +LYW D G + IE+S L
Sbjct: 3073 WTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLN 3132
Query: 541 GNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPN 600
G R +L+ L EPRA+ ++ G+++WTDWG I R GMDGS RS IV + WPN
Sbjct: 3133 GAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPN 3192
Query: 601 GLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD 660
GLTLD V +R+YW DA+ + I + DGS R ++L ++ + H F++T FED+VYWTDW+
Sbjct: 3193 GLTLDYVTERIYWADAREDYIEFASLDGSNRHVVL--SQDIPHIFALTLFEDYVYWTDWE 3250
Query: 661 KTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPA 719
++ RA+K G + + S TL PM +HV+H RQPD NH C NG CS+LCL +
Sbjct: 3251 TKSINRAHKTTGTNKTLLIS--TLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLS 3308
Query: 720 PRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
P G CACP L D + CV +
Sbjct: 3309 PGGGH-----KCACPTNFYLGSDGRTCVSN 3333
Score = 516 bits (1274), Expect = e-146
Identities = 284/755 (37%), Positives = 393/755 (52%), Gaps = 49/755 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C EF C RCI WKCD + DC D+SDE P +C + C RF+C + CIP
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCH--QHTCPSDRFKC-ENNRCIPN 910
Query: 83 SWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD DC + DE C C P +F+C G C+P++W CD + DC D SDE
Sbjct: 911 RWLCDGDNDCGNSEDESNATCSARTCPPNQFSCAS--GRCIPISWTCDLDDDCGDRSDES 968
Query: 141 A--CNETCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
A TC +FTC NG+CI + W E C + +C + F C G+
Sbjct: 969 ASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGC-SHSCS-STQFKCNSGR 1026
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECNDRITCVHRAWVXXXXX 254
CI W CDGD DC D SDE T + P C + EF+C C+ W
Sbjct: 1027 CIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDT 1086
Query: 255 XXXXXXXEALELCRGNVTCRLD---QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C G VT D +F CKD + CI A C+G DC D SDE NC
Sbjct: 1087 DCMDSSDE--KSCEG-VTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENC--- 1140
Query: 311 KTICDKRTEFDCGGG--MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCV 368
+++ + C +C+P K+CD + DC + DE + C ++C NNGGCS C
Sbjct: 1141 ESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEG-ELC--DQCSLNNGGCSHNCS 1197
Query: 369 DTP-IGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
P G C C G +L DN TC+ CA CSQ C K + KC C+ G+ +P
Sbjct: 1198 VAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEP- 1256
Query: 427 DRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDV 485
D C++ + P ++F+ +H+IR+I L + +V ++ ALD+ ++W+DV
Sbjct: 1257 DGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDV 1316
Query: 486 NDEKIYKAPI-DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGN 542
++KIY+ + D G T VVI L T +GLAVDW+ ++YW ++ + IE++ L G
Sbjct: 1317 VEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGT 1376
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDW-GQVPKIERAGMDGSHRSTI--VSYDVKWP 599
+R L+ +E PRAIAL+P +G +FWTDW +P+IE A M G+ R T+ + WP
Sbjct: 1377 LRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWP 1436
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDW 659
NGLT+D + +R+ W+DA+ + I S YDGSG +L E L HPF++T + VYWTDW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 660 DKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLCL 717
+ +ANK+ G +V + T+T P + VYHP RQP N C A G CSHLCL
Sbjct: 1497 RTNTLAKANKWTGHNVTVVQRTNT--QPFDLQVYHPSRQPMAPNPCEANGGQGPCSHLCL 1554
Query: 718 PAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
N VSCACP+ +KL D+ C E K+
Sbjct: 1555 ----INYNR-TVSCACPHLMKLHKDNTTCYEFKKF 1584
Score = 461 bits (1136), Expect = e-129
Identities = 267/760 (35%), Positives = 370/760 (48%), Gaps = 62/760 (8%)
Query: 22 TCTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
TC ++F+C T RCIP W CD + DC D SDE P CT +M C F C G CI
Sbjct: 3452 TCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCT--QMTCGVDEFRCKDSGRCI 3508
Query: 81 PRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
P W+CD DC DGSDE +C+ C P +F C K CVP W CD + DC D SD
Sbjct: 3509 PARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRC--KNNRCVPGRWQCDYDNDCGDNSD 3566
Query: 139 EKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
E++C C EF+C NG+CI RW E C TP C F C G
Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-TPRCD-MDQFQCKSGH 3624
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
CI W CD D DC DGSDE C + VR+ C EF+CN+ + C AW
Sbjct: 3625 CIPLRWRCDADADCMDGSDEEACGT--GVRT-CPLDEFQCNNTL-CKPLAWKCDGEDDCG 3680
Query: 258 XXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNC---TRQKTI 313
E E C V F+CK D C+ C+G +C DG+DE +C T T
Sbjct: 3681 DNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 3740
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQ--RCVD 369
C + EF C C+ S C+ DC + DE C N C RCV
Sbjct: 3741 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Query: 370 TPIGYYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
T YC C G+ + + C+DI+EC G+CSQ+C N KG C C + +
Sbjct: 3801 TEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFM---KTH 3857
Query: 429 TRCKATEGHPSLLF-ARKHDIRKISLDH----HEMVAIVNDTKSATALDYVFRTGMIFWS 483
CKA +L+ A ++IR + H +E +++ A+D + G ++W+
Sbjct: 3858 NTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT 3917
Query: 484 DVNDEKI----------------YKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWT 527
+ + I ++ ID G + G L G+A+DWV ++YWT
Sbjct: 3918 NWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISG--LKMPRGIAIDWVAGNVYWT 3975
Query: 528 DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSH 587
D+G + IE++ ++G RK LI ++EP AI ++PL G M+W+DWG PKIE A MDG+
Sbjct: 3976 DSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTL 4035
Query: 588 RSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSI 647
R T+V +++WP GL +D +R+YW DAK++ I S +G+ + S L HPFSI
Sbjct: 4036 RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSI 4095
Query: 648 TTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAA 707
FED++Y + V++ +KF + + T L + + +YH ++QP+ N C
Sbjct: 4096 DVFEDYIYGVTYINNRVFKIHKFGHSPL--VNLTGGLSHASDVVLYHQHKQPEVTNPCD- 4152
Query: 708 VNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C LCL +P GP C CPNG +L D+ CV
Sbjct: 4153 -RKKCEWLCLLSPS-GP-----VCTCPNGKRL--DNGTCV 4183
Score = 280 bits (686), Expect = 2e-74
Identities = 171/516 (33%), Positives = 267/516 (51%), Gaps = 41/516 (7%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVNDE------KIYKAPI 495
A +I L ++ I T+ TA+D+ + + W V D K + P
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPG 263
Query: 496 DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLE 553
+G + T+ I L + +A+DW+ + Y+ D + I + + G+ L+ L
Sbjct: 264 LKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELY 323
Query: 554 EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
P+ IAL+P G +F+TD+GQ+PK+ER MDG +R+ +V + +P+G+TLDLV + VYW
Sbjct: 324 NPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYW 383
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD------KTAVYRA 667
DA ++ I +Y+G GR+ I+ ++ H + +T FE+++Y T+ D KT+V R
Sbjct: 384 ADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV 442
Query: 668 NKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRF 722
N+FN + + +T + +H+YH RQP +H + G CS +CL A
Sbjct: 443 NRFNSTEYQVVT---RVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLA--- 496
Query: 723 GPNSPRV-SCACPNGLKLLPDDQMCVEDSKYHFLPF 757
NS + +C C +G L D + C + FL +
Sbjct: 497 --NSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVY 530
Score = 249 bits (609), Expect = 3e-65
Identities = 189/637 (29%), Positives = 272/637 (42%), Gaps = 58/637 (9%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC S F+C+ RCIP W CD + DC +S DE C+A C +F C S G CIP
Sbjct: 894 TCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSA--RTCPPNQFSCAS-GRCIP 950
Query: 82 RSWRCDATADCPDGSDEH-QCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
SW CD DC D SDE C C P +FTC G C+ + W CD++ DC D SDE
Sbjct: 951 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNN--GRCININWRCDNDNDCGDNSDE 1008
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPTCQP-----QSHFS 192
C+ +C S +F C +G+CI W E C +P F
Sbjct: 1009 AGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQ 1068
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C DG CI W CDGD DC D SDE C V P S +F C D C+ +AWV
Sbjct: 1069 CRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP--SVKFGCKDSARCISKAWVCD 1126
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTR 309
E E C ++ CR C +++ C+P C+G DC DGSDE
Sbjct: 1127 GDNDCEDNSDE--ENCE-SLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCD 1183
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDR-CG-ENECEKNNGGCSQR 366
Q ++ + +C + VC CP E P + C ++ C K+ CSQ+
Sbjct: 1184 QCSLNNGGCSHNC--SVAPGEGIVC----SCPLGMELGPDNHTCQIQSYCAKHL-KCSQK 1236
Query: 367 CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG-YARD 424
C C C +G+ L D +C + DP I N + + H G Y+
Sbjct: 1237 CDQNKFSVKCSCYEGWVLEPDGESCRSL----DPFKPFIIFSNRHEIRRIDLHKGDYSVL 1292
Query: 425 PRDRTRCKATEGHPSLLFARKHDI------RKISLDHHEMVA---IVN---DTKSATALD 472
A + H S D+ R LD+ + + ++ T A+D
Sbjct: 1293 VPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVD 1352
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
++ G I+W + N ++I A +D GT RT ++ + +A+D L+WTD +
Sbjct: 1353 WI--AGNIYWVESNLDQIEVAKLD-GTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDAS 1409
Query: 533 --HIELSDLQGNMRKILIRDRLEE--PRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
IE + + G R+ + R+ P + ++ LE + W D + I A DGS
Sbjct: 1410 LPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWID-ARSDAIYSARYDGSGH 1468
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
++ + + L VYW D + NT++ N
Sbjct: 1469 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKAN 1505
Score = 229 bits (561), Expect = 2e-59
Identities = 139/392 (35%), Positives = 182/392 (46%), Gaps = 29/392 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L S+ RTC T+S+F CK +CIP WKCD E DC D SDE P C K C+
Sbjct: 3321 FYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPD-CPEFK--CRPG 3377
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
+F+C S G+C ++ CD DC D SDE C++ C P +F C C+P + C+
Sbjct: 3378 QFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT-NTNRCIPGIFRCNG 3435
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQ 186
+C DG DE+ C E TC ++F C +CI WV E C TC
Sbjct: 3436 QDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC- 3494
Query: 187 PQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D G+CI A W CDG+ DC DGSDE + C +F C + CV
Sbjct: 3495 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERT---CEPYQFRCKNN-RCVP 3550
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
W E E C C +F C + CI G C+G DC DGSDE
Sbjct: 3551 GRWQCDYDNDCGDNSDE--ESCTPR-PCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 3607
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+CT + CD +F C G CIPL CD DC + DE G C + C+
Sbjct: 3608 DCTPR---CD-MDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN- 3662
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
+ P+ + CD E + + E+ +ECA
Sbjct: 3663 NTLCKPLAWKCDGEDD---CGDNSDENPEECA 3691
Score = 209 bits (511), Expect = 2e-53
Identities = 132/388 (34%), Positives = 199/388 (51%), Gaps = 32/388 (8%)
Query: 385 IDNRTCEDIDECADPGSCSQICI--NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
+ + CE+ D+ PG CS IC+ N C C +G++ D CK E L++
Sbjct: 473 VRSHACEN-DQYGKPGGCSDICLLANSHKARTCRCRSGFSLGS-DGKSCKKPEHELFLVY 530
Query: 443 ARKHD--IRKISL-----DHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
+ IR + + D H M+ I N + ALD+ TG I+++D I + I
Sbjct: 531 GKGRPGIIRGMDMGAKVPDEH-MIPIEN-LMNPRALDFHAETGFIYFADTTSYLIGRQKI 588
Query: 496 DEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDRL 552
D GT+R ++ + + +G+AVDW+ ++LYWTD G I ++ L+ RK LI ++
Sbjct: 589 D-GTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKM 647
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPK------IERAGMDGSHRSTIV-SYDVKWPNGLTLD 605
PRAI ++PL GWM+WTDW + PK +ERA MDGSHR V S V WPNGL+LD
Sbjct: 648 THPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLD 707
Query: 606 LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVY 665
+ R+YWVDA + I + +G+ R+++ E L H F + ++++WT++ +VY
Sbjct: 708 IPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPE-LNHAFGLCHHGNYLFWTEYRSGSVY 766
Query: 666 RANKFNGKDVEAITSTHTLQNPMV-IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGP 724
R + G +T + + P+ I +Y +Q G N C NG CS LCL P G
Sbjct: 767 RLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATP--GS 824
Query: 725 NSPRVSCACPNGLKLLPDDQMCVEDSKY 752
CAC L D C+ + Y
Sbjct: 825 R----QCACAEDQVLDADGVTCLANPSY 848
Score = 207 bits (506), Expect = 1e-52
Identities = 123/361 (34%), Positives = 198/361 (54%), Gaps = 23/361 (6%)
Query: 400 GSCSQICI-NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHD-IRKISLDHHE 457
G CSQ+C+ + T C C GY+ R+ +A EG S L H+ IR I LD ++
Sbjct: 1855 GDCSQLCLPTSETTRSCMCTAGYSL----RSGQQACEGVGSFLLYSVHEGIRGIPLDPND 1910
Query: 458 M---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ V+ T A +D+ I+W D+ I +A D+ T R V+ + +G
Sbjct: 1911 KSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQ-TWREDVVTNGIGRVEG 1969
Query: 515 LAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ 574
+AVDW+ ++YWTD G + IE++ L G+ R ++I L++PRAI ++P +G++FWT+WGQ
Sbjct: 1970 IAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQ 2029
Query: 575 VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYD-GSGRRL 633
P+IER+ +DG+ R +V+ + WPNG+++D ++YW DA+ + I + + G R +
Sbjct: 2030 YPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREV 2089
Query: 634 ILHSTEVLRHPFSITTFEDWVYWTDWDKT--AVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+L S + FS++ FED++YW+D ++ R +K N D + + +Q I
Sbjct: 2090 VLSSNNM--DMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQ-LKDIK 2146
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
V++ RQ G N CA NG C LCL R + +CAC +G+ L D C E +
Sbjct: 2147 VFNRDRQ-KGTNVCAVANGGCQQLCLYRGR-----GQRACACAHGM-LAEDGASCREYAG 2199
Query: 752 Y 752
Y
Sbjct: 2200 Y 2200
Score = 195 bits (476), Expect = 4e-49
Identities = 124/359 (34%), Positives = 153/359 (42%), Gaps = 39/359 (10%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
EF C G CI S CD C D SDE P+ C + + C++ +C S+G C+ C
Sbjct: 2529 EFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRR--CKKTFRQC-SNGRCVSNMLWC 2585
Query: 87 DATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
+ DC DGSDE C ACG EF CR G C+ + C+ DC D SDE C+ T
Sbjct: 2586 NGADDCGDGSDEIPCNKTACGVGEFRCR--DGTCIGNSSRCNQFVDCEDASDEMNCSATD 2643
Query: 147 RSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCP---TPTCQPQSHFS 192
S F G C WV E CP P C P ++F+
Sbjct: 2644 CSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC-PLNYFA 2702
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CD + DC G DE C C +FEC + C+ + W+
Sbjct: 2703 CPSGRCIPMSWTCDKEDDCEHGEDETHC------NKFCSEAQFECQNH-RCISKQWLCDG 2755
Query: 253 XXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDE---YNCT 308
EA C G TC F C H C+P C+G KDC DG+DE C
Sbjct: 2756 SDDCGDGSDEAAH-CEGK-TCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCL 2813
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD----RCGENECEKNNGGC 363
T CD R EF C CIP VCD DC + DE + CG +E NG C
Sbjct: 2814 YNST-CDDR-EFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRC 2870
Score = 176 bits (429), Expect = 2e-43
Identities = 116/372 (31%), Positives = 178/372 (47%), Gaps = 21/372 (5%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---H 455
G CS +C IN T C C + +D T C E LL+AR+ +IR + LD +
Sbjct: 1547 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCY--EFKKFLLYARQMEIRGVDLDAPYY 1603
Query: 456 HEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ +++ V D + T LDY R ++WSDV + I +A I+ GT V+ L + G
Sbjct: 1604 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFIN-GTGVETVVSADLPNAHG 1662
Query: 515 LAVDWVYNHLYWT--DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +L+WT DT I ++ L G+ + +++ LE+P + ++PL G ++WTD
Sbjct: 1663 LAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG-LEQPHGLVVHPLRGKLYWTDG 1721
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+R+ + S K P GL +D ++YW+ + +TI+ CN DGSG
Sbjct: 1722 DN---ISMANMDGSNRTLLFSGQ-KGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLE 1777
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I L ++ D ++W D + +K +G + ++ TL M ++
Sbjct: 1778 VIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYD 1837
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
G N C+ NG CS LCLP + SC C G L Q C +
Sbjct: 1838 ESIQLDHKGTNPCSVNNGDCSQLCLPT-----SETTRSCMCTAGYSLRSGQQACEGVGSF 1892
Query: 753 HFLPFYNNFRSI 764
+ R I
Sbjct: 1893 LLYSVHEGIRGI 1904
Score = 167 bits (405), Expect = 2e-40
Identities = 88/216 (40%), Positives = 107/216 (49%), Gaps = 19/216 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+RTC ++F C +GRCIP+SW CD + DC D SDE + T + F C ++G C
Sbjct: 933 ARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQ--FTC-NNGRC 989
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
I +WRCD DC D SDE C +C +F C G C+P W CD + DC D SDE
Sbjct: 990 ININWRCDNDNDCGDNSDEAGCS-HSCSSTQFKCNS--GRCIPEHWTCDGDNDCGDYSDE 1046
Query: 140 KACNET---------CRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP--TPTCQP 187
N T C +DEF C +G CI +RW E C T C P
Sbjct: 1047 THANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP 1106
Query: 188 QSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVS 222
F C D +CIS W CDGD DC D SDE C S
Sbjct: 1107 SVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCES 1142
Score = 153 bits (371), Expect = 2e-36
Identities = 110/369 (29%), Positives = 178/369 (48%), Gaps = 37/369 (10%)
Query: 400 GSCSQICINE-KGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISL-DHHE 457
G C Q+C+ +G C C G + D C+ G+ LL++ + ++ I L D
Sbjct: 2164 GGCQQLCLYRGRGQRACACAHGMLAE--DGASCREYAGY--LLYSERTILKSIHLSDERN 2219
Query: 458 MVAIVND------TKSATALDYVFRTGM-------IFWSDVNDEKIYKAPIDEGTQRTVV 504
+ A V K+ AL + +R G IF+SD++ I + D+G++R +
Sbjct: 2220 LNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQIN-DDGSRRITI 2278
Query: 505 IGEQLITSDGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEPRAI 558
+ E + + +GLA ++ LYWT T H + ++ + PRA
Sbjct: 2279 V-ENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAF 2337
Query: 559 ALNPLEGWMFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
L+ + MFWT+W Q P I RA + G++ T++ D++ PNGL +D +++Y+ DA
Sbjct: 2338 VLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDAT 2397
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ I C YDGS R +IL S V HPF + + + ++WTDW + AV RANK G +++
Sbjct: 2398 LDKIERCEYDGSHRYVILKSEPV--HPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMK- 2454
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ Q PM I ++ C NG C LCL + V+C+C G
Sbjct: 2455 LLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLT-----HQGHVNCSCRGG- 2508
Query: 738 KLLPDDQMC 746
++L DD C
Sbjct: 2509 RILQDDLTC 2517
Score = 147 bits (356), Expect = 1e-34
Identities = 75/214 (35%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C+ ++F C+ RCI W CD DC D SDE C F C +C
Sbjct: 2731 NKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSSFSCPGTHVC 2787
Query: 80 IPRSWRCDATADCPDGSDEH---QCEVEA-CGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+P W CD DC DG+DE C + C EF C+ + +C+P ++CD + DC+D
Sbjct: 2788 VPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNR--QCIPKHFVCDHDRDCAD 2845
Query: 136 GSDEK-ACN-ETCRSDEFTCGNGKCIQMR-WVXXXXXXXXXXXXEV----KCPTP--TCQ 186
GSDE C TC EF C NG+C+ R W E C +P C
Sbjct: 2846 GSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCN 2905
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C+ G+C++ C+G DC D SDE GC
Sbjct: 2906 ASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 2939
Score = 138 bits (333), Expect = 9e-32
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 9/148 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCT--ATKMV--CQEYRFECLS 75
S +C+S++F+C +GRCIP W CD + DC D SDE CT AT+ C F+C
Sbjct: 1012 SHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRL 1071
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCE--VEACGPE-EFTCRGKPGECVPLTWMCDDNPD 132
DGLCIP WRCD DC D SDE CE C P +F C+ C+ W+CD + D
Sbjct: 1072 DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDS-ARCISKAWVCDGDND 1130
Query: 133 CSDGSDEKACNE-TCRSDEFTCGNGKCI 159
C D SDE+ C CR C N +
Sbjct: 1131 CEDNSDEENCESLACRPPSHPCANNTSV 1158
Score = 133 bits (322), Expect = 2e-30
Identities = 115/385 (29%), Positives = 147/385 (38%), Gaps = 37/385 (9%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKC-DNEKDCSDSSD---EDPTVCTATKMVCQ-EYRFE 72
+++ +C S R G C L +CS +D C A C+ + FE
Sbjct: 2472 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFE 2531
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C ++G CI S CD C D SDE C C C G CV C+
Sbjct: 2532 C-ANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSN--GRCVSNMLWCNGA 2588
Query: 131 PDCSDGSDEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC DGSDE CN+T C EF C +G CI E+ C C
Sbjct: 2589 DDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYF 2648
Query: 190 HFS--------C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP-CISTEFECND 239
C C + W CDG DC D SDE C P V+ P C F C
Sbjct: 2649 RLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDC---PGVKRPRCPLNYFACPS 2705
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
C+ +W E N C QF+C++H CI C+G DC
Sbjct: 2706 G-RCIPMSWTCDKEDDCEHGEDET----HCNKFCSEAQFECQNHRCISKQWLCDGSDDCG 2760
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-C 356
DGSDE KT C + F C G +C+P +CD DC + DE C N C
Sbjct: 2761 DGSDEAAHCEGKT-CGP-SSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTC 2818
Query: 357 EKNNGGCSQR-CVDTPIGYYCDCEK 380
+ C R C+ P + CD ++
Sbjct: 2819 DDREFMCQNRQCI--PKHFVCDHDR 2841
Score = 111 bits (267), Expect = 9e-24
Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 17/153 (11%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLC 79
RTC EF+C C PL+WKCD E DC D+SDE+P C + VC R F C +D +C
Sbjct: 3652 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC--ARFVCPPNRPFRCKNDRVC 3709
Query: 80 IPRSWRCDATADCPDGSDEHQCE------VEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
+ +CD T +C DG+DE CE +EF CR + C+ + C+ DC
Sbjct: 3710 LWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ--RCLSSSLRCNMFDDC 3767
Query: 134 SDGSDEKACN-----ETCRSDEFTCGN-GKCIQ 160
DGSDE+ C+ +C ++ CG+ +C++
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Score = 92.3 bits (219), Expect = 6e-18
Identities = 51/150 (34%), Positives = 71/150 (47%), Gaps = 15/150 (10%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI- 80
TC EF C+ +CIP + CD+++DC+D SDE P T C F C ++G C+
Sbjct: 2817 TCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPT---CGPSEFRC-ANGRCLS 2872
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPE-------EFTCRGKPGECVPLTWMCDDNPDC 133
R W CD DC D SDE PE +F C G CV +C+ DC
Sbjct: 2873 SRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLC--SSGRCVAEALLCNGQDDC 2930
Query: 134 SDGSDEKACN-ETCRSDEFTCGNGKCIQMR 162
D SDE+ C+ C S + + + C ++
Sbjct: 2931 GDSSDERGCHINECLSRKLSGCSQDCEDLK 2960
Score = 91.1 bits (216), Expect = 1e-17
Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 37/397 (9%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECADPGSCSQICINEK--GTFKCECHT----------------GYARDPRDRTRCKATEG 436
E D I ++ T+ YA + +
Sbjct: 193 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAA 252
Query: 437 HPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
L AR ++ +H +++ A+D++ TG ++ D D++I+
Sbjct: 253 QTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWL--TGNFYFVDDIDDRIFVCN-R 309
Query: 497 EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEP 555
G ++ +L G+A+D +++TD G +E D+ G R L+ ++ P
Sbjct: 310 NGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFP 369
Query: 556 RAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I L+ + ++W D + IE +G R TI+
Sbjct: 370 HGITLDLVSRLVYWAD-AYLDYIEVVDYEGKGRQTII 405
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 85.4 bits (202), Expect = 7e-16
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 25/241 (10%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C+ Q F C +G+CI+ CDG C D SDE + C T +C++
Sbjct: 2523 SCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSR---RCKKTFRQCSNGRCV 2579
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ W E+ C + +F+C+D +CI + CN DC D SD
Sbjct: 2580 SNMLWCNGADDCGDGSD----EIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASD 2635
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC--PNFEDEPRDRCGENECEKNNG 361
E NC+ T C G + P C++ C P++ + + CG+ E++
Sbjct: 2636 EMNCS--ATDCSSYFRLGVKGVLFQP----CERTSLCYAPSWVCDGANDCGDYSDERDCP 2689
Query: 362 GCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC---ADPGSCSQICINEKGTFKCEC 417
G + RC P+ Y+ C G + + TC+ D+C D C++ C + F+C+
Sbjct: 2690 GVKRPRC---PLNYFA-CPSGRCIPMSWTCDKEDDCEHGEDETHCNKFC--SEAQFECQN 2743
Query: 418 H 418
H
Sbjct: 2744 H 2744
Score = 65.7 bits (153), Expect = 6e-10
Identities = 72/286 (25%), Positives = 118/286 (41%), Gaps = 35/286 (12%)
Query: 349 DRCGENECEKNNGGCSQRCVDT-PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICI 407
D G N C NNG CSQ C+ T C C GY L + C GS +
Sbjct: 1843 DHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQ-----QACEGVGSFLLYSV 1897
Query: 408 NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLL----FARKHD--------IRKISLDH 455
+E G G DP D++ SL F ++D + IS
Sbjct: 1898 HE-GI------RGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAK 1950
Query: 456 HEMV----AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLIT 511
+ + N + + G I+W+D + I A ++ G+ R VVI + L
Sbjct: 1951 RDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLN-GSFRYVVISQGLDK 2009
Query: 512 SDGLAVDWVYNHLYWTDTG-HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
+ V +L+WT+ G + IE S L G R +L+ + P I+++ +G ++W
Sbjct: 2010 PRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWC 2069
Query: 571 DWGQVPKIERAGMD-GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVD 615
D + KIER ++ G +R ++S + + ++ + +YW D
Sbjct: 2070 D-ARTDKIERIDLETGENREVVLSSNNM--DMFSVSVFEDFIYWSD 2112
Score = 53.6 bits (123), Expect = 3e-06
Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMCIP 329
CR++ C+D + + N C G D+ C + C + EF+C G CI
Sbjct: 2482 CRINNGGCQDLCLLTHQGHVNC--SCRGGRILQDDLTCRAVNSSCRAQDEFECANGECIN 2539
Query: 330 LSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKL 384
S CD C + DE C C+K CS RCV + +C DC G
Sbjct: 2540 FSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNML--WCNGADDCGDGSDE 2597
Query: 385 ID-NRTCEDIDE--CADPGSC 402
I N+T + E C D G+C
Sbjct: 2598 IPCNKTACGVGEFRCRD-GTC 2617
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 42.3 bits (95), Expect = 0.006
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 345 DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSC 402
D + + G N+C NNGGCS C+ TP C C + L D TC P C
Sbjct: 796 DAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQC 854
Score = 41.5 bits (93), Expect = 0.011
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
E + SS+F C +GRC+ + C+ + DC DSSDE
Sbjct: 2901 EHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDE 2936
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 16/91 (17%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDI------DECADPGSCSQICI 407
N C++ C C+ +P G C C G K +DN TC + + PG+C+ C
Sbjct: 4149 NPCDRKK--CEWLCLLSPSGPVCTCPNG-KRLDNGTCVPVPSPTPPPDAPRPGTCNLQCF 4205
Query: 408 NEKGTF-------KCECHTGYARDPRDRTRC 431
N F KC C Y D + +C
Sbjct: 4206 NGGSCFLNARRQPKCRCQPRYTGDKCELDQC 4236
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
protein protein.
Length = 4544
Score = 526 bits (1297), Expect = e-148
Identities = 289/750 (38%), Positives = 396/750 (52%), Gaps = 44/750 (5%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCTAT-KMVCQEYRFE-CLSDG 77
C EFRC+ G CI S +C+ DC D+SDE T C++ ++ + F+ C
Sbjct: 2605 CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTS 2664
Query: 78 LCIPRSWRCDATADCPDGSDEHQC---EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
LC SW CD DC D SDE C + C F C G C+P++W CD DC
Sbjct: 2665 LCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPS--GRCIPMSWTCDKEDDCE 2722
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK-CPTPTCQPQSHFSC 193
G DE CN+ C +F C N +CI +W+ E C TC P S FSC
Sbjct: 2723 HGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS-FSC 2781
Query: 194 TDGQ-CISAWWHCDGDVDCADGSDE---VGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
C+ W CDGD DCADG+DE GC+ S C EF C +R C+ + +V
Sbjct: 2782 PGTHVCVPERWLCDGDKDCADGADESIAAGCL----YNSTCDDREFMCQNR-QCIPKHFV 2836
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY--- 305
E+ E C TC +F+C + C+ + C+G DC D SDE
Sbjct: 2837 CDHDRDCADGSDESPE-CE-YPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKN 2894
Query: 306 -NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGC 363
+CT + C+ ++F C G C+ + +C+ DC + DE C NEC + GC
Sbjct: 2895 PHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERG--CHINECLSRKLSGC 2952
Query: 364 SQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYA 422
SQ C D IG+ C C G++L D+ RTC D+DEC+ CSQ CIN G++KC C GYA
Sbjct: 2953 SQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYA 3012
Query: 423 RDPRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIF 481
D CKA T+ P L+FA ++ +RK++LD + +A ALD+ +R MI+
Sbjct: 3013 PRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIY 3072
Query: 482 WSDVNDE-KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
W+DV + + + G+ V+ L DGLAVDWV +LYW D G + IE+S L
Sbjct: 3073 WTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLN 3132
Query: 541 GNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPN 600
G R +L+ L EPRA+ ++ G+++WTDWG I R GMDGS RS IV + WPN
Sbjct: 3133 GAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPN 3192
Query: 601 GLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD 660
GLTLD V +R+YW DA+ + I + DGS R ++L ++ + H F++T FED+VYWTDW+
Sbjct: 3193 GLTLDYVTERIYWADAREDYIEFASLDGSNRHVVL--SQDIPHIFALTLFEDYVYWTDWE 3250
Query: 661 KTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPA 719
++ RA+K G + + S TL PM +HV+H RQPD NH C NG CS+LCL +
Sbjct: 3251 TKSINRAHKTTGTNKTLLIS--TLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLS 3308
Query: 720 PRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
P G CACP L D + CV +
Sbjct: 3309 PGGGH-----KCACPTNFYLGSDGRTCVSN 3333
Score = 516 bits (1274), Expect = e-146
Identities = 284/755 (37%), Positives = 393/755 (52%), Gaps = 49/755 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C EF C RCI WKCD + DC D+SDE P +C + C RF+C + CIP
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCH--QHTCPSDRFKC-ENNRCIPN 910
Query: 83 SWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD DC + DE C C P +F+C G C+P++W CD + DC D SDE
Sbjct: 911 RWLCDGDNDCGNSEDESNATCSARTCPPNQFSCAS--GRCIPISWTCDLDDDCGDRSDES 968
Query: 141 A--CNETCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
A TC +FTC NG+CI + W E C + +C + F C G+
Sbjct: 969 ASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGC-SHSCS-STQFKCNSGR 1026
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECNDRITCVHRAWVXXXXX 254
CI W CDGD DC D SDE T + P C + EF+C C+ W
Sbjct: 1027 CIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDT 1086
Query: 255 XXXXXXXEALELCRGNVTCRLD---QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C G VT D +F CKD + CI A C+G DC D SDE NC
Sbjct: 1087 DCMDSSDE--KSCEG-VTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENC--- 1140
Query: 311 KTICDKRTEFDCGGG--MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCV 368
+++ + C +C+P K+CD + DC + DE + C ++C NNGGCS C
Sbjct: 1141 ESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEG-ELC--DQCSLNNGGCSHNCS 1197
Query: 369 DTP-IGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
P G C C G +L DN TC+ CA CSQ C K + KC C+ G+ +P
Sbjct: 1198 VAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEP- 1256
Query: 427 DRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDV 485
D C++ + P ++F+ +H+IR+I L + +V ++ ALD+ ++W+DV
Sbjct: 1257 DGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDV 1316
Query: 486 NDEKIYKAPI-DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGN 542
++KIY+ + D G T VVI L T +GLAVDW+ ++YW ++ + IE++ L G
Sbjct: 1317 VEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGT 1376
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDW-GQVPKIERAGMDGSHRSTI--VSYDVKWP 599
+R L+ +E PRAIAL+P +G +FWTDW +P+IE A M G+ R T+ + WP
Sbjct: 1377 LRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWP 1436
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDW 659
NGLT+D + +R+ W+DA+ + I S YDGSG +L E L HPF++T + VYWTDW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 660 DKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLCL 717
+ +ANK+ G +V + T+T P + VYHP RQP N C A G CSHLCL
Sbjct: 1497 RTNTLAKANKWTGHNVTVVQRTNT--QPFDLQVYHPSRQPMAPNPCEANGGQGPCSHLCL 1554
Query: 718 PAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
N VSCACP+ +KL D+ C E K+
Sbjct: 1555 ----INYNR-TVSCACPHLMKLHKDNTTCYEFKKF 1584
Score = 461 bits (1136), Expect = e-129
Identities = 267/760 (35%), Positives = 370/760 (48%), Gaps = 62/760 (8%)
Query: 22 TCTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
TC ++F+C T RCIP W CD + DC D SDE P CT +M C F C G CI
Sbjct: 3452 TCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCT--QMTCGVDEFRCKDSGRCI 3508
Query: 81 PRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
P W+CD DC DGSDE +C+ C P +F C K CVP W CD + DC D SD
Sbjct: 3509 PARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRC--KNNRCVPGRWQCDYDNDCGDNSD 3566
Query: 139 EKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
E++C C EF+C NG+CI RW E C TP C F C G
Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-TPRCD-MDQFQCKSGH 3624
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
CI W CD D DC DGSDE C + VR+ C EF+CN+ + C AW
Sbjct: 3625 CIPLRWRCDADADCMDGSDEEACGT--GVRT-CPLDEFQCNNTL-CKPLAWKCDGEDDCG 3680
Query: 258 XXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNC---TRQKTI 313
E E C V F+CK D C+ C+G +C DG+DE +C T T
Sbjct: 3681 DNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 3740
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQ--RCVD 369
C + EF C C+ S C+ DC + DE C N C RCV
Sbjct: 3741 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Query: 370 TPIGYYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
T YC C G+ + + C+DI+EC G+CSQ+C N KG C C + +
Sbjct: 3801 TEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFM---KTH 3857
Query: 429 TRCKATEGHPSLLF-ARKHDIRKISLDH----HEMVAIVNDTKSATALDYVFRTGMIFWS 483
CKA +L+ A ++IR + H +E +++ A+D + G ++W+
Sbjct: 3858 NTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT 3917
Query: 484 DVNDEKI----------------YKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWT 527
+ + I ++ ID G + G L G+A+DWV ++YWT
Sbjct: 3918 NWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISG--LKMPRGIAIDWVAGNVYWT 3975
Query: 528 DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSH 587
D+G + IE++ ++G RK LI ++EP AI ++PL G M+W+DWG PKIE A MDG+
Sbjct: 3976 DSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTL 4035
Query: 588 RSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSI 647
R T+V +++WP GL +D +R+YW DAK++ I S +G+ + S L HPFSI
Sbjct: 4036 RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSI 4095
Query: 648 TTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAA 707
FED++Y + V++ +KF + + T L + + +YH ++QP+ N C
Sbjct: 4096 DVFEDYIYGVTYINNRVFKIHKFGHSPL--VNLTGGLSHASDVVLYHQHKQPEVTNPCD- 4152
Query: 708 VNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C LCL +P GP C CPNG +L D+ CV
Sbjct: 4153 -RKKCEWLCLLSPS-GP-----VCTCPNGKRL--DNGTCV 4183
Score = 280 bits (686), Expect = 2e-74
Identities = 171/516 (33%), Positives = 267/516 (51%), Gaps = 41/516 (7%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVNDE------KIYKAPI 495
A +I L ++ I T+ TA+D+ + + W V D K + P
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPG 263
Query: 496 DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLE 553
+G + T+ I L + +A+DW+ + Y+ D + I + + G+ L+ L
Sbjct: 264 LKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELY 323
Query: 554 EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
P+ IAL+P G +F+TD+GQ+PK+ER MDG +R+ +V + +P+G+TLDLV + VYW
Sbjct: 324 NPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYW 383
Query: 614 VDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD------KTAVYRA 667
DA ++ I +Y+G GR+ I+ ++ H + +T FE+++Y T+ D KT+V R
Sbjct: 384 ADAYLDYIEVVDYEGKGRQTIIQGI-LIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV 442
Query: 668 NKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRF 722
N+FN + + +T + +H+YH RQP +H + G CS +CL A
Sbjct: 443 NRFNSTEYQVVT---RVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLA--- 496
Query: 723 GPNSPRV-SCACPNGLKLLPDDQMCVEDSKYHFLPF 757
NS + +C C +G L D + C + FL +
Sbjct: 497 --NSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVY 530
Score = 249 bits (609), Expect = 3e-65
Identities = 189/637 (29%), Positives = 272/637 (42%), Gaps = 58/637 (9%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC S F+C+ RCIP W CD + DC +S DE C+A C +F C S G CIP
Sbjct: 894 TCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSA--RTCPPNQFSCAS-GRCIP 950
Query: 82 RSWRCDATADCPDGSDEH-QCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
SW CD DC D SDE C C P +FTC G C+ + W CD++ DC D SDE
Sbjct: 951 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNN--GRCININWRCDNDNDCGDNSDE 1008
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPTCQP-----QSHFS 192
C+ +C S +F C +G+CI W E C +P F
Sbjct: 1009 AGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQ 1068
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C DG CI W CDGD DC D SDE C V P S +F C D C+ +AWV
Sbjct: 1069 CRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP--SVKFGCKDSARCISKAWVCD 1126
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTR 309
E E C ++ CR C +++ C+P C+G DC DGSDE
Sbjct: 1127 GDNDCEDNSDE--ENCE-SLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCD 1183
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCP-NFEDEPRDR-CG-ENECEKNNGGCSQR 366
Q ++ + +C + VC CP E P + C ++ C K+ CSQ+
Sbjct: 1184 QCSLNNGGCSHNC--SVAPGEGIVC----SCPLGMELGPDNHTCQIQSYCAKHL-KCSQK 1236
Query: 367 CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG-YARD 424
C C C +G+ L D +C + DP I N + + H G Y+
Sbjct: 1237 CDQNKFSVKCSCYEGWVLEPDGESCRSL----DPFKPFIIFSNRHEIRRIDLHKGDYSVL 1292
Query: 425 PRDRTRCKATEGHPSLLFARKHDI------RKISLDHHEMVA---IVN---DTKSATALD 472
A + H S D+ R LD+ + + ++ T A+D
Sbjct: 1293 VPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVD 1352
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
++ G I+W + N ++I A +D GT RT ++ + +A+D L+WTD +
Sbjct: 1353 WI--AGNIYWVESNLDQIEVAKLD-GTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDAS 1409
Query: 533 --HIELSDLQGNMRKILIRDRLEE--PRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHR 588
IE + + G R+ + R+ P + ++ LE + W D + I A DGS
Sbjct: 1410 LPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWID-ARSDAIYSARYDGSGH 1468
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
++ + + L VYW D + NT++ N
Sbjct: 1469 MEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKAN 1505
Score = 229 bits (561), Expect = 2e-59
Identities = 139/392 (35%), Positives = 182/392 (46%), Gaps = 29/392 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L S+ RTC T+S+F CK +CIP WKCD E DC D SDE P C K C+
Sbjct: 3321 FYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPD-CPEFK--CRPG 3377
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
+F+C S G+C ++ CD DC D SDE C++ C P +F C C+P + C+
Sbjct: 3378 QFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT-NTNRCIPGIFRCNG 3435
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQ 186
+C DG DE+ C E TC ++F C +CI WV E C TC
Sbjct: 3436 QDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC- 3494
Query: 187 PQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D G+CI A W CDG+ DC DGSDE + C +F C + CV
Sbjct: 3495 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERT---CEPYQFRCKNN-RCVP 3550
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
W E E C C +F C + CI G C+G DC DGSDE
Sbjct: 3551 GRWQCDYDNDCGDNSDE--ESCTPR-PCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 3607
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+CT + CD +F C G CIPL CD DC + DE G C + C+
Sbjct: 3608 DCTPR---CD-MDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN- 3662
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
+ P+ + CD E + + E+ +ECA
Sbjct: 3663 NTLCKPLAWKCDGEDD---CGDNSDENPEECA 3691
Score = 209 bits (511), Expect = 2e-53
Identities = 132/388 (34%), Positives = 199/388 (51%), Gaps = 32/388 (8%)
Query: 385 IDNRTCEDIDECADPGSCSQICI--NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
+ + CE+ D+ PG CS IC+ N C C +G++ D CK E L++
Sbjct: 473 VRSHACEN-DQYGKPGGCSDICLLANSHKARTCRCRSGFSLGS-DGKSCKKPEHELFLVY 530
Query: 443 ARKHD--IRKISL-----DHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
+ IR + + D H M+ I N + ALD+ TG I+++D I + I
Sbjct: 531 GKGRPGIIRGMDMGAKVPDEH-MIPIEN-LMNPRALDFHAETGFIYFADTTSYLIGRQKI 588
Query: 496 DEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDRL 552
D GT+R ++ + + +G+AVDW+ ++LYWTD G I ++ L+ RK LI ++
Sbjct: 589 D-GTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKM 647
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPK------IERAGMDGSHRSTIV-SYDVKWPNGLTLD 605
PRAI ++PL GWM+WTDW + PK +ERA MDGSHR V S V WPNGL+LD
Sbjct: 648 THPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLD 707
Query: 606 LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVY 665
+ R+YWVDA + I + +G+ R+++ E L H F + ++++WT++ +VY
Sbjct: 708 IPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPE-LNHAFGLCHHGNYLFWTEYRSGSVY 766
Query: 666 RANKFNGKDVEAITSTHTLQNPMV-IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGP 724
R + G +T + + P+ I +Y +Q G N C NG CS LCL P G
Sbjct: 767 RLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATP--GS 824
Query: 725 NSPRVSCACPNGLKLLPDDQMCVEDSKY 752
CAC L D C+ + Y
Sbjct: 825 R----QCACAEDQVLDADGVTCLANPSY 848
Score = 207 bits (506), Expect = 1e-52
Identities = 123/361 (34%), Positives = 198/361 (54%), Gaps = 23/361 (6%)
Query: 400 GSCSQICI-NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHD-IRKISLDHHE 457
G CSQ+C+ + T C C GY+ R+ +A EG S L H+ IR I LD ++
Sbjct: 1855 GDCSQLCLPTSETTRSCMCTAGYSL----RSGQQACEGVGSFLLYSVHEGIRGIPLDPND 1910
Query: 458 M---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ V+ T A +D+ I+W D+ I +A D+ T R V+ + +G
Sbjct: 1911 KSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQ-TWREDVVTNGIGRVEG 1969
Query: 515 LAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ 574
+AVDW+ ++YWTD G + IE++ L G+ R ++I L++PRAI ++P +G++FWT+WGQ
Sbjct: 1970 IAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQ 2029
Query: 575 VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYD-GSGRRL 633
P+IER+ +DG+ R +V+ + WPNG+++D ++YW DA+ + I + + G R +
Sbjct: 2030 YPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREV 2089
Query: 634 ILHSTEVLRHPFSITTFEDWVYWTDWDKT--AVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+L S + FS++ FED++YW+D ++ R +K N D + + +Q I
Sbjct: 2090 VLSSNNM--DMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQ-LKDIK 2146
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSK 751
V++ RQ G N CA NG C LCL R + +CAC +G+ L D C E +
Sbjct: 2147 VFNRDRQ-KGTNVCAVANGGCQQLCLYRGR-----GQRACACAHGM-LAEDGASCREYAG 2199
Query: 752 Y 752
Y
Sbjct: 2200 Y 2200
Score = 195 bits (476), Expect = 4e-49
Identities = 124/359 (34%), Positives = 153/359 (42%), Gaps = 39/359 (10%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
EF C G CI S CD C D SDE P+ C + + C++ +C S+G C+ C
Sbjct: 2529 EFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRR--CKKTFRQC-SNGRCVSNMLWC 2585
Query: 87 DATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
+ DC DGSDE C ACG EF CR G C+ + C+ DC D SDE C+ T
Sbjct: 2586 NGADDCGDGSDEIPCNKTACGVGEFRCR--DGTCIGNSSRCNQFVDCEDASDEMNCSATD 2643
Query: 147 RSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCP---TPTCQPQSHFS 192
S F G C WV E CP P C P ++F+
Sbjct: 2644 CSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC-PLNYFA 2702
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CD + DC G DE C C +FEC + C+ + W+
Sbjct: 2703 CPSGRCIPMSWTCDKEDDCEHGEDETHC------NKFCSEAQFECQNH-RCISKQWLCDG 2755
Query: 253 XXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDE---YNCT 308
EA C G TC F C H C+P C+G KDC DG+DE C
Sbjct: 2756 SDDCGDGSDEAAH-CEGK-TCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCL 2813
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD----RCGENECEKNNGGC 363
T CD R EF C CIP VCD DC + DE + CG +E NG C
Sbjct: 2814 YNST-CDDR-EFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRC 2870
Score = 176 bits (429), Expect = 2e-43
Identities = 116/372 (31%), Positives = 178/372 (47%), Gaps = 21/372 (5%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---H 455
G CS +C IN T C C + +D T C E LL+AR+ +IR + LD +
Sbjct: 1547 GPCSHLCLINYNRTVSCAC-PHLMKLHKDNTTCY--EFKKFLLYARQMEIRGVDLDAPYY 1603
Query: 456 HEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
+ +++ V D + T LDY R ++WSDV + I +A I+ GT V+ L + G
Sbjct: 1604 NYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFIN-GTGVETVVSADLPNAHG 1662
Query: 515 LAVDWVYNHLYWT--DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +L+WT DT I ++ L G+ + +++ LE+P + ++PL G ++WTD
Sbjct: 1663 LAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQG-LEQPHGLVVHPLRGKLYWTDG 1721
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+R+ + S K P GL +D ++YW+ + +TI+ CN DGSG
Sbjct: 1722 DN---ISMANMDGSNRTLLFSGQ-KGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLE 1777
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I L ++ D ++W D + +K +G + ++ TL M ++
Sbjct: 1778 VIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYD 1837
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
G N C+ NG CS LCLP + SC C G L Q C +
Sbjct: 1838 ESIQLDHKGTNPCSVNNGDCSQLCLPT-----SETTRSCMCTAGYSLRSGQQACEGVGSF 1892
Query: 753 HFLPFYNNFRSI 764
+ R I
Sbjct: 1893 LLYSVHEGIRGI 1904
Score = 167 bits (405), Expect = 2e-40
Identities = 88/216 (40%), Positives = 107/216 (49%), Gaps = 19/216 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+RTC ++F C +GRCIP+SW CD + DC D SDE + T + F C ++G C
Sbjct: 933 ARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQ--FTC-NNGRC 989
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
I +WRCD DC D SDE C +C +F C G C+P W CD + DC D SDE
Sbjct: 990 ININWRCDNDNDCGDNSDEAGCS-HSCSSTQFKCNS--GRCIPEHWTCDGDNDCGDYSDE 1046
Query: 140 KACNET---------CRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP--TPTCQP 187
N T C +DEF C +G CI +RW E C T C P
Sbjct: 1047 THANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDP 1106
Query: 188 QSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVS 222
F C D +CIS W CDGD DC D SDE C S
Sbjct: 1107 SVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCES 1142
Score = 153 bits (371), Expect = 2e-36
Identities = 110/369 (29%), Positives = 178/369 (48%), Gaps = 37/369 (10%)
Query: 400 GSCSQICINE-KGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISL-DHHE 457
G C Q+C+ +G C C G + D C+ G+ LL++ + ++ I L D
Sbjct: 2164 GGCQQLCLYRGRGQRACACAHGMLAE--DGASCREYAGY--LLYSERTILKSIHLSDERN 2219
Query: 458 MVAIVND------TKSATALDYVFRTGM-------IFWSDVNDEKIYKAPIDEGTQRTVV 504
+ A V K+ AL + +R G IF+SD++ I + D+G++R +
Sbjct: 2220 LNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQIN-DDGSRRITI 2278
Query: 505 IGEQLITSDGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEPRAI 558
+ E + + +GLA ++ LYWT T H + ++ + PRA
Sbjct: 2279 V-ENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAF 2337
Query: 559 ALNPLEGWMFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
L+ + MFWT+W Q P I RA + G++ T++ D++ PNGL +D +++Y+ DA
Sbjct: 2338 VLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDAT 2397
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
++ I C YDGS R +IL S V HPF + + + ++WTDW + AV RANK G +++
Sbjct: 2398 LDKIERCEYDGSHRYVILKSEPV--HPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMK- 2454
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ Q PM I ++ C NG C LCL + V+C+C G
Sbjct: 2455 LLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLT-----HQGHVNCSCRGG- 2508
Query: 738 KLLPDDQMC 746
++L DD C
Sbjct: 2509 RILQDDLTC 2517
Score = 147 bits (356), Expect = 1e-34
Identities = 75/214 (35%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C+ ++F C+ RCI W CD DC D SDE C F C +C
Sbjct: 2731 NKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSSFSCPGTHVC 2787
Query: 80 IPRSWRCDATADCPDGSDEH---QCEVEA-CGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+P W CD DC DG+DE C + C EF C+ + +C+P ++CD + DC+D
Sbjct: 2788 VPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNR--QCIPKHFVCDHDRDCAD 2845
Query: 136 GSDEK-ACN-ETCRSDEFTCGNGKCIQMR-WVXXXXXXXXXXXXEV----KCPTP--TCQ 186
GSDE C TC EF C NG+C+ R W E C +P C
Sbjct: 2846 GSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCN 2905
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C+ G+C++ C+G DC D SDE GC
Sbjct: 2906 ASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 2939
Score = 138 bits (333), Expect = 9e-32
Identities = 63/148 (42%), Positives = 79/148 (53%), Gaps = 9/148 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCT--ATKMV--CQEYRFECLS 75
S +C+S++F+C +GRCIP W CD + DC D SDE CT AT+ C F+C
Sbjct: 1012 SHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRL 1071
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCE--VEACGPE-EFTCRGKPGECVPLTWMCDDNPD 132
DGLCIP WRCD DC D SDE CE C P +F C+ C+ W+CD + D
Sbjct: 1072 DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDS-ARCISKAWVCDGDND 1130
Query: 133 CSDGSDEKACNE-TCRSDEFTCGNGKCI 159
C D SDE+ C CR C N +
Sbjct: 1131 CEDNSDEENCESLACRPPSHPCANNTSV 1158
Score = 133 bits (322), Expect = 2e-30
Identities = 115/385 (29%), Positives = 147/385 (38%), Gaps = 37/385 (9%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKC-DNEKDCSDSSD---EDPTVCTATKMVCQ-EYRFE 72
+++ +C S R G C L +CS +D C A C+ + FE
Sbjct: 2472 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFE 2531
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C ++G CI S CD C D SDE C C C G CV C+
Sbjct: 2532 C-ANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSN--GRCVSNMLWCNGA 2588
Query: 131 PDCSDGSDEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC DGSDE CN+T C EF C +G CI E+ C C
Sbjct: 2589 DDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYF 2648
Query: 190 HFS--------C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP-CISTEFECND 239
C C + W CDG DC D SDE C P V+ P C F C
Sbjct: 2649 RLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDC---PGVKRPRCPLNYFACPS 2705
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
C+ +W E N C QF+C++H CI C+G DC
Sbjct: 2706 G-RCIPMSWTCDKEDDCEHGEDET----HCNKFCSEAQFECQNHRCISKQWLCDGSDDCG 2760
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-C 356
DGSDE KT C + F C G +C+P +CD DC + DE C N C
Sbjct: 2761 DGSDEAAHCEGKT-CGP-SSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTC 2818
Query: 357 EKNNGGCSQR-CVDTPIGYYCDCEK 380
+ C R C+ P + CD ++
Sbjct: 2819 DDREFMCQNRQCI--PKHFVCDHDR 2841
Score = 111 bits (267), Expect = 9e-24
Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 17/153 (11%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLC 79
RTC EF+C C PL+WKCD E DC D+SDE+P C + VC R F C +D +C
Sbjct: 3652 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC--ARFVCPPNRPFRCKNDRVC 3709
Query: 80 IPRSWRCDATADCPDGSDEHQCE------VEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
+ +CD T +C DG+DE CE +EF CR + C+ + C+ DC
Sbjct: 3710 LWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ--RCLSSSLRCNMFDDC 3767
Query: 134 SDGSDEKACN-----ETCRSDEFTCGN-GKCIQ 160
DGSDE+ C+ +C ++ CG+ +C++
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Score = 92.3 bits (219), Expect = 6e-18
Identities = 51/150 (34%), Positives = 71/150 (47%), Gaps = 15/150 (10%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI- 80
TC EF C+ +CIP + CD+++DC+D SDE P T C F C ++G C+
Sbjct: 2817 TCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPT---CGPSEFRC-ANGRCLS 2872
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPE-------EFTCRGKPGECVPLTWMCDDNPDC 133
R W CD DC D SDE PE +F C G CV +C+ DC
Sbjct: 2873 SRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLC--SSGRCVAEALLCNGQDDC 2930
Query: 134 SDGSDEKACN-ETCRSDEFTCGNGKCIQMR 162
D SDE+ C+ C S + + + C ++
Sbjct: 2931 GDSSDERGCHINECLSRKLSGCSQDCEDLK 2960
Score = 91.1 bits (216), Expect = 1e-17
Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 37/397 (9%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECADPGSCSQICINEK--GTFKCECHT----------------GYARDPRDRTRCKATEG 436
E D I ++ T+ YA + +
Sbjct: 193 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAA 252
Query: 437 HPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
L AR ++ +H +++ A+D++ TG ++ D D++I+
Sbjct: 253 QTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWL--TGNFYFVDDIDDRIFVCN-R 309
Query: 497 EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEP 555
G ++ +L G+A+D +++TD G +E D+ G R L+ ++ P
Sbjct: 310 NGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFP 369
Query: 556 RAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I L+ + ++W D + IE +G R TI+
Sbjct: 370 HGITLDLVSRLVYWAD-AYLDYIEVVDYEGKGRQTII 405
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 85.4 bits (202), Expect = 7e-16
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 25/241 (10%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C+ Q F C +G+CI+ CDG C D SDE + C T +C++
Sbjct: 2523 SCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSR---RCKKTFRQCSNGRCV 2579
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ W E+ C + +F+C+D +CI + CN DC D SD
Sbjct: 2580 SNMLWCNGADDCGDGSD----EIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASD 2635
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC--PNFEDEPRDRCGENECEKNNG 361
E NC+ T C G + P C++ C P++ + + CG+ E++
Sbjct: 2636 EMNCS--ATDCSSYFRLGVKGVLFQP----CERTSLCYAPSWVCDGANDCGDYSDERDCP 2689
Query: 362 GCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC---ADPGSCSQICINEKGTFKCEC 417
G + RC P+ Y+ C G + + TC+ D+C D C++ C + F+C+
Sbjct: 2690 GVKRPRC---PLNYFA-CPSGRCIPMSWTCDKEDDCEHGEDETHCNKFC--SEAQFECQN 2743
Query: 418 H 418
H
Sbjct: 2744 H 2744
Score = 65.7 bits (153), Expect = 6e-10
Identities = 72/286 (25%), Positives = 118/286 (41%), Gaps = 35/286 (12%)
Query: 349 DRCGENECEKNNGGCSQRCVDT-PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICI 407
D G N C NNG CSQ C+ T C C GY L + C GS +
Sbjct: 1843 DHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQ-----QACEGVGSFLLYSV 1897
Query: 408 NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLL----FARKHD--------IRKISLDH 455
+E G G DP D++ SL F ++D + IS
Sbjct: 1898 HE-GI------RGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAK 1950
Query: 456 HEMV----AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLIT 511
+ + N + + G I+W+D + I A ++ G+ R VVI + L
Sbjct: 1951 RDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLN-GSFRYVVISQGLDK 2009
Query: 512 SDGLAVDWVYNHLYWTDTG-HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
+ V +L+WT+ G + IE S L G R +L+ + P I+++ +G ++W
Sbjct: 2010 PRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWC 2069
Query: 571 DWGQVPKIERAGMD-GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVD 615
D + KIER ++ G +R ++S + + ++ + +YW D
Sbjct: 2070 D-ARTDKIERIDLETGENREVVLSSNNM--DMFSVSVFEDFIYWSD 2112
Score = 53.6 bits (123), Expect = 3e-06
Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMCIP 329
CR++ C+D + + N C G D+ C + C + EF+C G CI
Sbjct: 2482 CRINNGGCQDLCLLTHQGHVNC--SCRGGRILQDDLTCRAVNSSCRAQDEFECANGECIN 2539
Query: 330 LSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKL 384
S CD C + DE C C+K CS RCV + +C DC G
Sbjct: 2540 FSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNML--WCNGADDCGDGSDE 2597
Query: 385 ID-NRTCEDIDE--CADPGSC 402
I N+T + E C D G+C
Sbjct: 2598 IPCNKTACGVGEFRCRD-GTC 2617
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 42.3 bits (95), Expect = 0.006
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 345 DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSC 402
D + + G N+C NNGGCS C+ TP C C + L D TC P C
Sbjct: 796 DAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQC 854
Score = 41.5 bits (93), Expect = 0.011
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
E + SS+F C +GRC+ + C+ + DC DSSDE
Sbjct: 2901 EHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDE 2936
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 16/91 (17%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDI------DECADPGSCSQICI 407
N C++ C C+ +P G C C G K +DN TC + + PG+C+ C
Sbjct: 4149 NPCDRKK--CEWLCLLSPSGPVCTCPNG-KRLDNGTCVPVPSPTPPPDAPRPGTCNLQCF 4205
Query: 408 NEKGTF-------KCECHTGYARDPRDRTRC 431
N F KC C Y D + +C
Sbjct: 4206 NGGSCFLNARRQPKCRCQPRYTGDKCELDQC 4236
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
lipoprotein-related protein 1 variant protein.
Length = 2359
Score = 526 bits (1297), Expect = e-148
Identities = 289/750 (38%), Positives = 396/750 (52%), Gaps = 44/750 (5%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCTAT-KMVCQEYRFE-CLSDG 77
C EFRC+ G CI S +C+ DC D+SDE T C++ ++ + F+ C
Sbjct: 421 CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTS 480
Query: 78 LCIPRSWRCDATADCPDGSDEHQC---EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
LC SW CD DC D SDE C + C F C G C+P++W CD DC
Sbjct: 481 LCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPS--GRCIPMSWTCDKEDDCE 538
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK-CPTPTCQPQSHFSC 193
G DE CN+ C +F C N +CI +W+ E C TC P S FSC
Sbjct: 539 HGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS-FSC 597
Query: 194 TDGQ-CISAWWHCDGDVDCADGSDE---VGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
C+ W CDGD DCADG+DE GC+ S C EF C +R C+ + +V
Sbjct: 598 PGTHVCVPERWLCDGDKDCADGADESIAAGCL----YNSTCDDREFMCQNR-QCIPKHFV 652
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY--- 305
E+ E C TC +F+C + C+ + C+G DC D SDE
Sbjct: 653 CDHDRDCADGSDESPE-CE-YPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKN 710
Query: 306 -NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGC 363
+CT + C+ ++F C G C+ + +C+ DC + DE C NEC + GC
Sbjct: 711 PHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERG--CHINECLSRKLSGC 768
Query: 364 SQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYA 422
SQ C D IG+ C C G++L D+ RTC D+DEC+ CSQ CIN G++KC C GYA
Sbjct: 769 SQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYA 828
Query: 423 RDPRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIF 481
D CKA T+ P L+FA ++ +RK++LD + +A ALD+ +R MI+
Sbjct: 829 PRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIY 888
Query: 482 WSDVNDE-KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
W+DV + + + G+ V+ L DGLAVDWV +LYW D G + IE+S L
Sbjct: 889 WTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLN 948
Query: 541 GNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPN 600
G R +L+ L EPRA+ ++ G+++WTDWG I R GMDGS RS IV + WPN
Sbjct: 949 GAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPN 1008
Query: 601 GLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD 660
GLTLD V +R+YW DA+ + I + DGS R ++L ++ + H F++T FED+VYWTDW+
Sbjct: 1009 GLTLDYVTERIYWADAREDYIEFASLDGSNRHVVL--SQDIPHIFALTLFEDYVYWTDWE 1066
Query: 661 KTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPA 719
++ RA+K G + + S TL PM +HV+H RQPD NH C NG CS+LCL +
Sbjct: 1067 TKSINRAHKTTGTNKTLLIS--TLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLS 1124
Query: 720 PRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
P G CACP L D + CV +
Sbjct: 1125 PGGGH-----KCACPTNFYLGSDGRTCVSN 1149
Score = 457 bits (1127), Expect = e-128
Identities = 267/760 (35%), Positives = 370/760 (48%), Gaps = 63/760 (8%)
Query: 22 TCTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
TC ++F+C T RCIP W CD + DC D SDE P CT +M C F C G CI
Sbjct: 1268 TCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCT--QMTCGVDEFRCKDSGRCI 1324
Query: 81 PRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
P W+CD DC DGSDE +C+ C P +F C K CVP W CD + DC D SD
Sbjct: 1325 PARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRC--KNNRCVPGRWQCDYDNDCGDNSD 1382
Query: 139 EKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
E++C C EF+C NG+CI RW E C TP C F C G
Sbjct: 1383 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-TPRCD-MDQFQCKSGH 1440
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
CI W CD D DC DGSDE C + VR+ C EF+CN+ + C AW
Sbjct: 1441 CIPLRWRCDADADCMDGSDEEACGT--GVRT-CPLDEFQCNNTL-CKPLAWKCDGEDDCG 1496
Query: 258 XXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNC---TRQKTI 313
E E C V F+CK D C+ C+G +C DG+DE +C T T
Sbjct: 1497 DNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 1556
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQ--RCVD 369
C + EF C C+ S C+ DC + DE C N C RCV
Sbjct: 1557 CKDKKEFLCRNQRCLS-SLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 1615
Query: 370 TPIGYYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
T YC C G+ + + C+DI+EC G+CSQ+C N KG C C + +
Sbjct: 1616 TEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFM---KTH 1672
Query: 429 TRCKATEGHPSLLF-ARKHDIRKISLDH----HEMVAIVNDTKSATALDYVFRTGMIFWS 483
CKA +L+ A ++IR + H +E +++ A+D + G ++W+
Sbjct: 1673 NTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWT 1732
Query: 484 DVNDEKI----------------YKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWT 527
+ + I ++ ID G + G L G+A+DWV ++YWT
Sbjct: 1733 NWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISG--LKMPRGIAIDWVAGNVYWT 1790
Query: 528 DTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSH 587
D+G + IE++ ++G RK LI ++EP AI ++PL G M+W+DWG PKIE A MDG+
Sbjct: 1791 DSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTL 1850
Query: 588 RSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSI 647
R T+V +++WP GL +D +R+YW DAK++ I S +G+ + S L HPFSI
Sbjct: 1851 RETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSI 1910
Query: 648 TTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAA 707
FED++Y + V++ +KF + + T L + + +YH ++QP+ N C
Sbjct: 1911 DVFEDYIYGVTYINNRVFKIHKFGHSPL--VNLTGGLSHASDVVLYHQHKQPEVTNPCD- 1967
Query: 708 VNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C LCL +P GP C CPNG +L D+ CV
Sbjct: 1968 -RKKCEWLCLLSPS-GP-----VCTCPNGKRL--DNGTCV 1998
Score = 229 bits (561), Expect = 2e-59
Identities = 139/392 (35%), Positives = 182/392 (46%), Gaps = 29/392 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L S+ RTC T+S+F CK +CIP WKCD E DC D SDE P C K C+
Sbjct: 1137 FYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPD-CPEFK--CRPG 1193
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
+F+C S G+C ++ CD DC D SDE C++ C P +F C C+P + C+
Sbjct: 1194 QFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT-NTNRCIPGIFRCNG 1251
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQ 186
+C DG DE+ C E TC ++F C +CI WV E C TC
Sbjct: 1252 QDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC- 1310
Query: 187 PQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D G+CI A W CDG+ DC DGSDE + C +F C + CV
Sbjct: 1311 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERT---CEPYQFRCKNN-RCVP 1366
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
W E E C C +F C + CI G C+G DC DGSDE
Sbjct: 1367 GRWQCDYDNDCGDNSDE--ESCTPR-PCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 1423
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+CT + CD +F C G CIPL CD DC + DE G C + C+
Sbjct: 1424 DCTPR---CD-MDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN- 1478
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
+ P+ + CD E + + E+ +ECA
Sbjct: 1479 NTLCKPLAWKCDGEDD---CGDNSDENPEECA 1507
Score = 195 bits (476), Expect = 4e-49
Identities = 124/359 (34%), Positives = 153/359 (42%), Gaps = 39/359 (10%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
EF C G CI S CD C D SDE P+ C + + C++ +C S+G C+ C
Sbjct: 345 EFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRR--CKKTFRQC-SNGRCVSNMLWC 401
Query: 87 DATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
+ DC DGSDE C ACG EF CR G C+ + C+ DC D SDE C+ T
Sbjct: 402 NGADDCGDGSDEIPCNKTACGVGEFRCR--DGTCIGNSSRCNQFVDCEDASDEMNCSATD 459
Query: 147 RSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCP---TPTCQPQSHFS 192
S F G C WV E CP P C P ++F+
Sbjct: 460 CSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRC-PLNYFA 518
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CD + DC G DE C C +FEC + C+ + W+
Sbjct: 519 CPSGRCIPMSWTCDKEDDCEHGEDETHC------NKFCSEAQFECQNH-RCISKQWLCDG 571
Query: 253 XXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDE---YNCT 308
EA C G TC F C H C+P C+G KDC DG+DE C
Sbjct: 572 SDDCGDGSDEAAH-CEGK-TCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCL 629
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRD----RCGENECEKNNGGC 363
T CD R EF C CIP VCD DC + DE + CG +E NG C
Sbjct: 630 YNST-CDDR-EFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRC 686
Score = 147 bits (356), Expect = 1e-34
Identities = 75/214 (35%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C+ ++F C+ RCI W CD DC D SDE C F C +C
Sbjct: 547 NKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE---AAHCEGKTCGPSSFSCPGTHVC 603
Query: 80 IPRSWRCDATADCPDGSDEH---QCEVEA-CGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+P W CD DC DG+DE C + C EF C+ + +C+P ++CD + DC+D
Sbjct: 604 VPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNR--QCIPKHFVCDHDRDCAD 661
Query: 136 GSDEK-ACN-ETCRSDEFTCGNGKCIQMR-WVXXXXXXXXXXXXEV----KCPTP--TCQ 186
GSDE C TC EF C NG+C+ R W E C +P C
Sbjct: 662 GSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCN 721
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C+ G+C++ C+G DC D SDE GC
Sbjct: 722 ASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 755
Score = 141 bits (342), Expect = 7e-33
Identities = 92/295 (31%), Positives = 148/295 (50%), Gaps = 25/295 (8%)
Query: 466 KSATALDYVFRTGM-------IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
K+ AL + +R G IF+SD++ I + D+G++R ++ E + + +GLA
Sbjct: 50 KNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQIN-DDGSRRITIV-ENVGSVEGLAYH 107
Query: 519 WVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
++ LYWT T H + ++ + PRA L+ + MFWT+W
Sbjct: 108 RGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNW 167
Query: 573 G-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
Q P I RA + G++ T++ D++ PNGL +D +++Y+ DA ++ I C YDGS R
Sbjct: 168 NEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHR 227
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
+IL S V HPF + + + ++WTDW + AV RANK G +++ + Q PM I
Sbjct: 228 YVILKSEPV--HPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMK-LLRVDIPQQPMGII 284
Query: 692 VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
++ C NG C LCL + V+C+C G ++L DD C
Sbjct: 285 AVANDTNSCELSPCRINNGGCQDLCLLT-----HQGHVNCSCRGG-RILQDDLTC 333
Score = 133 bits (322), Expect = 2e-30
Identities = 115/385 (29%), Positives = 147/385 (38%), Gaps = 37/385 (9%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKC-DNEKDCSDSSD---EDPTVCTATKMVCQ-EYRFE 72
+++ +C S R G C L +CS +D C A C+ + FE
Sbjct: 288 NDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFE 347
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C ++G CI S CD C D SDE C C C G CV C+
Sbjct: 348 C-ANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSN--GRCVSNMLWCNGA 404
Query: 131 PDCSDGSDEKACNET-CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC DGSDE CN+T C EF C +G CI E+ C C
Sbjct: 405 DDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYF 464
Query: 190 HFS--------C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP-CISTEFECND 239
C C + W CDG DC D SDE C P V+ P C F C
Sbjct: 465 RLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDC---PGVKRPRCPLNYFACPS 521
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
C+ +W E N C QF+C++H CI C+G DC
Sbjct: 522 G-RCIPMSWTCDKEDDCEHGEDET----HCNKFCSEAQFECQNHRCISKQWLCDGSDDCG 576
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-C 356
DGSDE KT C + F C G +C+P +CD DC + DE C N C
Sbjct: 577 DGSDEAAHCEGKT-CGP-SSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTC 634
Query: 357 EKNNGGCSQR-CVDTPIGYYCDCEK 380
+ C R C+ P + CD ++
Sbjct: 635 DDREFMCQNRQCI--PKHFVCDHDR 657
Score = 107 bits (258), Expect = 1e-22
Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 18/153 (11%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLC 79
RTC EF+C C PL+WKCD E DC D+SDE+P C + VC R F C +D +C
Sbjct: 1468 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC--ARFVCPPNRPFRCKNDRVC 1525
Query: 80 IPRSWRCDATADCPDGSDEHQCE------VEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
+ +CD T +C DG+DE CE +EF CR + C+ + C+ DC
Sbjct: 1526 LWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ--RCLS-SLRCNMFDDC 1582
Query: 134 SDGSDEKACN-----ETCRSDEFTCGN-GKCIQ 160
DGSDE+ C+ +C ++ CG+ +C++
Sbjct: 1583 GDGSDEEDCSIDPKLTSCATNASICGDEARCVR 1615
Score = 92.3 bits (219), Expect = 6e-18
Identities = 51/150 (34%), Positives = 71/150 (47%), Gaps = 15/150 (10%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI- 80
TC EF C+ +CIP + CD+++DC+D SDE P T C F C ++G C+
Sbjct: 633 TCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPT---CGPSEFRC-ANGRCLS 688
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPE-------EFTCRGKPGECVPLTWMCDDNPDC 133
R W CD DC D SDE PE +F C G CV +C+ DC
Sbjct: 689 SRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLC--SSGRCVAEALLCNGQDDC 746
Query: 134 SDGSDEKACN-ETCRSDEFTCGNGKCIQMR 162
D SDE+ C+ C S + + + C ++
Sbjct: 747 GDSSDERGCHINECLSRKLSGCSQDCEDLK 776
Score = 85.4 bits (202), Expect = 7e-16
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 25/241 (10%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C+ Q F C +G+CI+ CDG C D SDE + C T +C++
Sbjct: 339 SCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSR---RCKKTFRQCSNGRCV 395
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ W E+ C + +F+C+D +CI + CN DC D SD
Sbjct: 396 SNMLWCNGADDCGDGSD----EIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASD 451
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC--PNFEDEPRDRCGENECEKNNG 361
E NC+ T C G + P C++ C P++ + + CG+ E++
Sbjct: 452 EMNCS--ATDCSSYFRLGVKGVLFQP----CERTSLCYAPSWVCDGANDCGDYSDERDCP 505
Query: 362 GCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC---ADPGSCSQICINEKGTFKCEC 417
G + RC P+ Y+ C G + + TC+ D+C D C++ C + F+C+
Sbjct: 506 GVKRPRC---PLNYFA-CPSGRCIPMSWTCDKEDDCEHGEDETHCNKFC--SEAQFECQN 559
Query: 418 H 418
H
Sbjct: 560 H 560
Score = 59.3 bits (137), Expect = 5e-08
Identities = 53/217 (24%), Positives = 95/217 (43%), Gaps = 16/217 (7%)
Query: 430 RCKATEGHPS-LLFARKH--DIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVN 486
R + G P+ + F+ H +I++I+ D + IV + S L Y ++W+
Sbjct: 60 RAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYT 119
Query: 487 DEKIYKAPIDEGTQRTVVIGEQLITSDG------LAVDWVYNHLYWTDTGHNH--IELSD 538
I + +D+ T+ E +IT G +D N ++WT+ H I +
Sbjct: 120 TSTITRHTVDQ-TRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHPSIMRAA 178
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
L G LI + P +A++ ++++D + KIER DGSHR I+ +
Sbjct: 179 LSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSD-ATLDKIERCEYDGSHRYVILKSEPVH 237
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLI 634
P GL + + ++W D + N + GS +L+
Sbjct: 238 PFGLA--VYGEHIFWTDWVRRAVQRANKHVGSNMKLL 272
Score = 53.6 bits (123), Expect = 3e-06
Identities = 42/141 (29%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMCIP 329
CR++ C+D + + N C G D+ C + C + EF+C G CI
Sbjct: 298 CRINNGGCQDLCLLTHQGHVNC--SCRGGRILQDDLTCRAVNSSCRAQDEFECANGECIN 355
Query: 330 LSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKL 384
S CD C + DE C C+K CS RCV + +C DC G
Sbjct: 356 FSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNML--WCNGADDCGDGSDE 413
Query: 385 ID-NRTCEDIDE--CADPGSC 402
I N+T + E C D G+C
Sbjct: 414 IPCNKTACGVGEFRCRD-GTC 433
Score = 41.5 bits (93), Expect = 0.011
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
E + SS+F C +GRC+ + C+ + DC DSSDE
Sbjct: 717 EHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDE 752
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 16/91 (17%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDI------DECADPGSCSQICI 407
N C++ C C+ +P G C C G K +DN TC + + PG+C+ C
Sbjct: 1964 NPCDRKK--CEWLCLLSPSGPVCTCPNG-KRLDNGTCVPVPSPTPPPDAPRPGTCNLQCF 2020
Query: 408 NEKGTF-------KCECHTGYARDPRDRTRC 431
N F KC C Y D + +C
Sbjct: 2021 NGGSCFLNARRQPKCRCQPRYTGDKCELDQC 2051
>AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 700
Score = 510 bits (1258), Expect = e-144
Identities = 238/579 (41%), Positives = 341/579 (58%), Gaps = 21/579 (3%)
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDR 240
P C+ + F C + +CI + W CD D DC D SDE C PK C ++F C D
Sbjct: 43 PAKDCE-KDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDC---PK--KTCADSDFTC-DN 95
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQC--KDHSCIPGALYCNGVKDC 298
C+H W E+ C V C ++ C H C+P + C+G KDC
Sbjct: 96 GHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCVPASWRCDGEKDC 154
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
G+DE C C + EF CG G C+ K C++ DCP+ DE G NEC
Sbjct: 155 EGGADEAGCATSLGTC-RGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLH 213
Query: 359 NNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECH 418
NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N KG FKCEC+
Sbjct: 214 NNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECY 273
Query: 419 TGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRT 477
GY D + CKA G PSL+F +H++R+I L ++ K+ ALD T
Sbjct: 274 PGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVAT 332
Query: 478 GMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHI 534
I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+YWTD+G+ I
Sbjct: 333 NRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTI 392
Query: 535 ELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSY 594
++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G R T+VS
Sbjct: 393 SVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSD 452
Query: 595 DVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWV 654
+++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF I FED V
Sbjct: 453 NIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKV 512
Query: 655 YWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC---AAVNGH 711
+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C NG
Sbjct: 513 FWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDACELSVQPNGG 570
Query: 712 CSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
C +LCLPAP+ +SP+ +CACP+ + L PD + C D+
Sbjct: 571 CEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRDA 609
Score = 140 bits (340), Expect = 1e-32
Identities = 60/145 (41%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNE---TCRSDEFTCGNGKCI 159
DE C TCR DEF CG+G C+
Sbjct: 159 DEAGCATSLGTCRGDEFQCGDGTCV 183
Score = 114 bits (275), Expect = 1e-24
Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 9/141 (6%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFEC-LSDGLC 79
+TC S+F C G CI WKCD E++C D SDE C TK VC + C + C
Sbjct: 84 KTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATC--TKQVCPAEKLSCGPTSHKC 141
Query: 80 IPRSWRCDATADCPDGSDEHQC--EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
+P SWRCD DC G+DE C + C +EF C G CV C+ DC DGS
Sbjct: 142 VPASWRCDGEKDCEGGADEAGCATSLGTCRGDEFQC--GDGTCVLAIKHCNQEQDCPDGS 199
Query: 138 DEKACNETCRSDEFTCGNGKC 158
DE C + +E NG C
Sbjct: 200 DEAGCLQGL--NECLHNNGGC 218
Score = 110 bits (264), Expect = 2e-23
Identities = 55/144 (38%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC-NETCRSDEFTCGNGKCIQMRWV 164
C ++F CR + C+P W CD++ DC D SDE C +TC +FTC NG CI RW
Sbjct: 47 CEKDQFQCRNE--RCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWK 104
Query: 165 XXXXXX--XXXXXXEVKCPTPTCQPQSHFSC--TDGQCISAWWHCDGDVDCADGSDEVGC 220
E C C P SC T +C+ A W CDG+ DC G+DE GC
Sbjct: 105 CDGEEECPDGSDESEATCTKQVC-PAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 221 VSTPKVRSPCISTEFECNDRITCV 244
++ C EF+C D TCV
Sbjct: 164 ATS---LGTCRGDEFQCGDG-TCV 183
>AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 700
Score = 510 bits (1258), Expect = e-144
Identities = 238/579 (41%), Positives = 341/579 (58%), Gaps = 21/579 (3%)
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDR 240
P C+ + F C + +CI + W CD D DC D SDE C PK C ++F C D
Sbjct: 43 PAKDCE-KDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDC---PK--KTCADSDFTC-DN 95
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQC--KDHSCIPGALYCNGVKDC 298
C+H W E+ C V C ++ C H C+P + C+G KDC
Sbjct: 96 GHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCVPASWRCDGEKDC 154
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
G+DE C C + EF CG G C+ K C++ DCP+ DE G NEC
Sbjct: 155 EGGADEAGCATSLGTC-RGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLH 213
Query: 359 NNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECH 418
NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N KG FKCEC+
Sbjct: 214 NNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECY 273
Query: 419 TGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRT 477
GY D + CKA G PSL+F +H++R+I L ++ K+ ALD T
Sbjct: 274 PGYEMDLLTKN-CKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVAT 332
Query: 478 GMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHI 534
I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H+YWTD+G+ I
Sbjct: 333 NRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTI 392
Query: 535 ELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSY 594
++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G R T+VS
Sbjct: 393 SVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSD 452
Query: 595 DVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWV 654
+++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF I FED V
Sbjct: 453 NIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKV 512
Query: 655 YWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC---AAVNGH 711
+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C NG
Sbjct: 513 FWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDACELSVQPNGG 570
Query: 712 CSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
C +LCLPAP+ +SP+ +CACP+ + L PD + C D+
Sbjct: 571 CEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRDA 609
Score = 140 bits (340), Expect = 1e-32
Identities = 60/145 (41%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNE---TCRSDEFTCGNGKCI 159
DE C TCR DEF CG+G C+
Sbjct: 159 DEAGCATSLGTCRGDEFQCGDGTCV 183
Score = 114 bits (275), Expect = 1e-24
Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 9/141 (6%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFEC-LSDGLC 79
+TC S+F C G CI WKCD E++C D SDE C TK VC + C + C
Sbjct: 84 KTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATC--TKQVCPAEKLSCGPTSHKC 141
Query: 80 IPRSWRCDATADCPDGSDEHQC--EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
+P SWRCD DC G+DE C + C +EF C G CV C+ DC DGS
Sbjct: 142 VPASWRCDGEKDCEGGADEAGCATSLGTCRGDEFQC--GDGTCVLAIKHCNQEQDCPDGS 199
Query: 138 DEKACNETCRSDEFTCGNGKC 158
DE C + +E NG C
Sbjct: 200 DEAGCLQGL--NECLHNNGGC 218
Score = 110 bits (264), Expect = 2e-23
Identities = 55/144 (38%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC-NETCRSDEFTCGNGKCIQMRWV 164
C ++F CR + C+P W CD++ DC D SDE C +TC +FTC NG CI RW
Sbjct: 47 CEKDQFQCRNE--RCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWK 104
Query: 165 XXXXXX--XXXXXXEVKCPTPTCQPQSHFSC--TDGQCISAWWHCDGDVDCADGSDEVGC 220
E C C P SC T +C+ A W CDG+ DC G+DE GC
Sbjct: 105 CDGEEECPDGSDESEATCTKQVC-PAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGC 163
Query: 221 VSTPKVRSPCISTEFECNDRITCV 244
++ C EF+C D TCV
Sbjct: 164 ATS---LGTCRGDEFQCGDG-TCV 183
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 499 bits (1230), Expect = e-140
Identities = 275/756 (36%), Positives = 391/756 (51%), Gaps = 51/756 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C + EFRCK CI WKCD + DC D SDED C C + +F+C + CIP+
Sbjct: 845 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHS--CPDDQFKC-QNNRCIPK 901
Query: 83 SWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD DC DE C C ++F+C G C+P W+CD DC D +DE
Sbjct: 902 RWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGN--GRCIPRAWLCDREDDCGDQTDEM 959
Query: 141 ACNE--TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
A E TC +F C +G+CI +W EV C +C + F C+ G+
Sbjct: 960 ASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGC-VHSCF-DNQFRCSSGR 1017
Query: 198 CISAWWHCDGDVDCADGSDE--VGCVSTPKVRSP--CISTEFECNDRITCVHRAWVXXXX 253
CI W CDGD DC D SDE + C ++ SP C EF+C+ CV W
Sbjct: 1018 CIPGHWACDGDNDCGDFSDEAQINCTKE-EIHSPAGCNGNEFQCHPDGNCVPDLWRCDGE 1076
Query: 254 XXXXXXXXEALELCRGNVT-C-RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E + C G + C +F C CI A C+G DC D SDE +C
Sbjct: 1077 KDCEDGSDE--KGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDC--D 1132
Query: 311 KTICDKRTEFDCGG--GMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCV 368
+C + C +C+ K+C+ DCP+ DE C +EC NNGGCS C
Sbjct: 1133 SFLCGP-PKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGY-LC--DECSLNNGGCSNHCS 1188
Query: 369 DTP-IGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
P G C C +G +L DN+TCE +D C++ CSQ+C K T KC C+ G+ D
Sbjct: 1189 VVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDV- 1247
Query: 427 DRTRCKATEGHPS-LLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDV 485
D C + + + ++F+ +H+IR+I L + +V ++ ALD+ F +++W+DV
Sbjct: 1248 DGESCTSVDPFEAFIIFSIRHEIRRIDLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDV 1307
Query: 486 NDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGN 542
+++IY+ + E + VV+ L T +GL VDW+ ++YW D+ + IE++ L G+
Sbjct: 1308 VEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGS 1367
Query: 543 MRKILIRDRLEEPRAIALNPLEGWMFWTDW-GQVPKIERAGMDGSHRSTIVSYDVK---W 598
+R LI +E PRAIAL+P G +FWTDW P+IE A M G+ R TI D+K W
Sbjct: 1368 LRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYK-DMKTGAW 1426
Query: 599 PNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTD 658
PNGLT+D +R+ W DA+ + I S YDG+ I+ E L HPF+++ + VYWTD
Sbjct: 1427 PNGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTD 1486
Query: 659 WDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLC 716
W + +ANK+ G++V I T P + +YHP RQP N CAA +G CSH+C
Sbjct: 1487 WRTNTLSKANKWTGQNVSVIQKTSA--QPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMC 1544
Query: 717 LPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
L ++ +CACP+ +KL D + C E K+
Sbjct: 1545 LI-----NHNRSAACACPHLMKLSSDKKTCYEMKKF 1575
Score = 467 bits (1151), Expect = e-131
Identities = 272/752 (36%), Positives = 383/752 (50%), Gaps = 49/752 (6%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCTAT-KMVCQEYRF-ECLSD 76
TC + EFRC G CIP S +C+ DC+D+SDE + T CT K+ + F C S
Sbjct: 2590 TCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNST 2649
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVE---ACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
LC+ +W CD + DC D SDE +C V+ C F+C G C+ TW+CD DC
Sbjct: 2650 SLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPS--GRCILNTWICDGQKDC 2707
Query: 134 SDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHF 191
DG DE C+ +C ++F C KCI W+ E C TC F
Sbjct: 2708 EDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADM-F 2766
Query: 192 SCTDGQ-CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
SC + C+ W CDG+ DC DGSDE+ + C F C++++ C+ + +V
Sbjct: 2767 SCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAP-NNTCDENAFMCHNKV-CIPKQFVC 2824
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY---- 305
E+ + C G C ++F C D C+ + C+G DCPD SDE
Sbjct: 2825 DHDDDCGDGSDESPQ-C-GYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNP 2882
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGCS 364
C + C+ + F C G CIP +CD DC + DE C NEC K GCS
Sbjct: 2883 KCKSAEQSCNS-SFFMCKNGRCIPSGGLCDNKDDCGDGSDERN--CHINECLSKKVSGCS 2939
Query: 365 QRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYAR 423
Q C D P+ Y C C G++L D+ +TC DIDEC+ CSQ CIN GT+KC C GY
Sbjct: 2940 QDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEI 2999
Query: 424 DPRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFW 482
P + CK+ ++ P L+ A H+IRKIS D + + A+D+ +R I+W
Sbjct: 3000 QPDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYW 3059
Query: 483 SDV---NDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDL 539
D N +I + ++ G+ VV + LAVDW+ +LYW+DT IE+S L
Sbjct: 3060 IDSSRPNGSRINRMCLN-GSDIKVV--HNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKL 3116
Query: 540 QGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWP 599
G IL+ RL+ PR ++L+P G+++W D + P I R GMDG+++S ++ + P
Sbjct: 3117 NGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRP 3176
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDW 659
LT+D V +R+YW D N I N DGS R + + + ++T FED++YWTD
Sbjct: 3177 MALTIDYVNRRLYWADE--NHIEFSNMDGSHRHKV--PNQDIPGVIALTLFEDYIYWTDG 3232
Query: 660 DKTAVYRANKFNGKD-VEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCL 717
++ RA+K +G D + I S H + + I VYH YRQPD H C NG CSHLCL
Sbjct: 3233 KTKSLSRAHKTSGADRLSLIYSWHAITD---IQVYHSYRQPDVSKHLCMINNGGCSHLCL 3289
Query: 718 PAPRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
AP +CACP L D++ C+ +
Sbjct: 3290 LAP-----GKTHTCACPTNFYLAADNRTCLSN 3316
Score = 380 bits (936), Expect = e-105
Identities = 249/775 (32%), Positives = 361/775 (46%), Gaps = 78/775 (10%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED---PTVCTATKMVCQEYRFECLS 75
+ +TC EF+CK CIP W+CD++ DCSD+SDE+ P CT +C +
Sbjct: 3472 DKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC--------A 3523
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+G C+ + CD DC DGSDE CE +C ++F C G+C+P W CD + DC
Sbjct: 3524 NGDCVSSRFWCDGDFDCADGSDERNCET-SCSKDQFRCSN--GQCIPAKWKCDGHEDCKY 3580
Query: 136 GSDEKAC---NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFS 192
G DEK+C + TC S E+ C + CI E+ C T C+ + F
Sbjct: 3581 GEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTE-CK-EDQFR 3638
Query: 193 CTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C + CI W CDG DC DGSDE C + C + EF CN+ + +H WV
Sbjct: 3639 CKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNI---CRADEFLCNNSLCKLH-FWVCD 3694
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
EA ++C + +C+++ C+ CNG+ +C D SDE +C +
Sbjct: 3695 GEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGK 3754
Query: 311 KTI----CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGCS 364
T C K+ EF C CIP+ CD+ DC + DE R E CE N C
Sbjct: 3755 LTYKARPC-KKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCG 3813
Query: 365 QR--CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C +C C+ G++ + NR CED++EC G+CS CIN +G++KC C +
Sbjct: 3814 DDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNF 3873
Query: 422 ARDPRDRTRCKATEGHPSLLF-ARKHDIR------KISLDHHEMVAIVNDTKSATALDYV 474
R+ T C A +L+ A DI S DH ++ I ++++ T +D
Sbjct: 3874 --QERNNT-CIAEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSR-ITGMDVY 3929
Query: 475 FRTGMIFWS-DVNDEKIYKAPIDEGTQRTV---VIGEQLITSDGLAVDWVYNHLYWTDTG 530
++ MI WS N I+ I +R +I + +AVDWV ++YWTD
Sbjct: 3930 YQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHS 3989
Query: 531 HNH---------------IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV 575
H I + L G L+ + EP AIA+NP G M+WT G
Sbjct: 3990 RMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDH 4049
Query: 576 PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A MDG+ R +V +++ P GL +D +R+YW D +++ I S YDGS + +
Sbjct: 4050 SHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSV 4109
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
S + L HP I FED++Y K V+R KF VE + + + + H
Sbjct: 4110 SSKQGLLHPHRIDIFEDYIYGAG-PKNGVFRVQKFGHGSVEYLAL--NIDKTKGVLISHR 4166
Query: 696 YRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
Y+Q D N C ++ C LCL N +C CP G L+ + C +DS
Sbjct: 4167 YKQLDLPNPC--LDLACEFLCL------LNPSGATCVCPEGKYLI--NGTCNDDS 4211
Score = 263 bits (645), Expect = 1e-69
Identities = 169/519 (32%), Positives = 257/519 (49%), Gaps = 38/519 (7%)
Query: 268 RGNVTCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDC-G 323
R C +F C DH +C+ + C+G DCPD SDE C + I C G
Sbjct: 27 RDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLG 86
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C+ LS++C+ +DCP+ DE C E + C++ N C +C C CE G
Sbjct: 87 TNKCVHLSQLCNGVLDCPDGYDEGV-HCQELLSNCQQLN--CQYKCTMVRNSTRCYCEDG 143
Query: 382 YKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEG 436
+++ D R+C+D DECA G+CSQ C N G++ C C GY P +R+ CKA T+
Sbjct: 144 FEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRS-CKAKIEPTDR 202
Query: 437 HPSLLFARKHDIRKISLDHHEMVAI--VNDTKSATALDYVFRTGMIFWSDV----NDEKI 490
P LL A I L+ +M + VN + T LD+++ MI W + N K
Sbjct: 203 PPILLIANFETIEVFYLNGSKMATLSSVNGNEIHT-LDFIYNEDMICWIESRESSNQLKC 261
Query: 491 YKAPIDEGT--QRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILI 548
+ G + T+ I + +A+DW+ +LY+ D + I + + G++ LI
Sbjct: 262 IQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHVGDRIFVCNSNGSVCVTLI 321
Query: 549 RDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
L P+AIA++P+ G +F+TD+G V K+ER MDG +R+ I+ + P L LDLV
Sbjct: 322 DLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALALDLVN 381
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+ VYWVD ++ + +Y G R ++ +V RH + IT FED++Y T+ D + R N
Sbjct: 382 KLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQV-RHLYGITVFEDYLYATNSDNYNIVRIN 440
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRFG 723
+FNG D+ ++ ++N I +Y QP +H V+ G CSH+CL + +
Sbjct: 441 RFNGTDIHSLIK---IENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYK 497
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHFLPFYNNFR 762
+C C G L D + C FL FY R
Sbjct: 498 TR----TCRCRTGFNLGSDGRSCKRPKNELFL-FYGKGR 531
Score = 260 bits (636), Expect = 2e-68
Identities = 193/721 (26%), Positives = 323/721 (44%), Gaps = 74/721 (10%)
Query: 22 TCTSSEFRCKTGR-CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+C+ F+CKT + CI W CD + DC+D+SDE K C + F+C ++ CI
Sbjct: 3435 SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE----ANCDKKTCGPHEFQCKNNN-CI 3489
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
P WRCD+ DC D SDE C+ + C ++F C G+CV + CD + DC+DGSDE+
Sbjct: 3490 PDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCAN--GDCVSSRFWCDGDFDCADGSDER 3547
Query: 141 ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQPQSHFSCTDGQC 198
C +C D+F C NG+CI +W E C +PTC + + +DG C
Sbjct: 3548 NCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG-C 3606
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
ISA C+G+ DCADGSDE+ CV + C +F C ++ C+ W+
Sbjct: 3607 ISASLKCNGEYDCADGSDEMDCV------TECKEDQFRCKNKAHCIPIRWLCDGIHDCVD 3660
Query: 259 XXXEALELC-RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E E C RG CR D+F C + C C+G DC D SDE K +C
Sbjct: 3661 GSDE--ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPST 3718
Query: 318 TEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCG------ENECEKNNGGCS-QRCVD 369
C +C+ ++C+ +C + DE D CG C+K+ CS ++C+
Sbjct: 3719 RPHRCRNNRICLQSEQMCNGIDECGDNSDE--DHCGGKLTYKARPCKKDEFACSNKKCI- 3775
Query: 370 TPIGYYC----DC-----EKGYKLIDNR-TCED-IDECADPGSCSQICINEKGTFKCECH 418
P+ C DC E+G ++ TCED ++ C D C+QI K + C C
Sbjct: 3776 -PMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQI----KTSVFCRCK 3830
Query: 419 TGYARDPRDRTRCKATEGHPSLLFAR-KHDIRKISLDHHEMVAIVN-DTKSATALDYVFR 476
G+ R+ ++R +C+ + + L+F H + ++ V N ++ T +
Sbjct: 3831 PGFQRNMKNR-QCE--DLNECLVFGTCSHQCINVE-GSYKCVCDQNFQERNNTCIAEGSE 3886
Query: 477 TGMIFWSDVNDEKIYKAPID-EGTQRTVVIGEQLITSDGLAVDWVYNHLYW-TDTGHNHI 534
+++ ++ D + P + G + + E G+ V + + + W T I
Sbjct: 3887 DQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGI 3946
Query: 535 ELSDLQGNMRKI----LIRDRLEEPRAIALNPLEGWMFWTD-------------WGQVP- 576
+ G ++ LI + PR IA++ + G ++WTD W +
Sbjct: 3947 FYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRY 4006
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW-VDAKMNTISSCNYDGSGRRLIL 635
I ++G + + +++ P + ++ R +YW V + I DG+ RR+++
Sbjct: 4007 SINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILV 4066
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
++ F + +YW D++ + + V +++S L +P I ++
Sbjct: 4067 QKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFED 4126
Query: 696 Y 696
Y
Sbjct: 4127 Y 4127
Score = 232 bits (568), Expect = 3e-60
Identities = 200/682 (29%), Positives = 301/682 (44%), Gaps = 73/682 (10%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE-DPTVCTATKMVCQEYRFECL 74
L+ E+R+C C RCIP CD E DC D+SDE D V T C F C
Sbjct: 2545 LYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST-----CATVEFRC- 2598
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEAC------GPEE--FTCRGKPGECVPLTWM 126
+DG CIPRS RC+ DC D SDE C C G + F CV TW+
Sbjct: 2599 ADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWI 2658
Query: 127 CDDNPDCSDGSDEKAC----NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPT 182
CD + DC D SDE C C + F+C +G+CI W+ E C +
Sbjct: 2659 CDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDS 2718
Query: 183 PTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
+C + F+C+ +CIS W CDG+ DC DG DE + C + F C
Sbjct: 2719 -SCS-WNQFACSAQKCISKHWICDGEDDCGDGLDESDSICG---AITCAADMFSCQGSRA 2773
Query: 243 CVHRAWVXXXXXXXXXXXXE-ALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDG 301
CV R W+ E + C N TC + F C + CIP C+ DC DG
Sbjct: 2774 CVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDG 2833
Query: 302 SDEY-NCTRQKTICDKRTEFDCGGGMCIPLSK-VCDKHVDCPNFEDE----PRDRCGENE 355
SDE C ++ C EF C G C+ ++ CD DCP+ DE P+ + E
Sbjct: 2834 SDESPQCGYRQ--CGTE-EFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQS 2890
Query: 356 CEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKLIDNRTCEDIDECADP--GSCSQICIN 408
C + C RC+ P G C DC G D R C I+EC CSQ C +
Sbjct: 2891 CNSSFFMCKNGRCI--PSGGLCDNKDDCGDG---SDERNCH-INECLSKKVSGCSQDCQD 2944
Query: 409 EKGTFKCECHTGYARDPRDRTRC----KATEGHP-SLLFARKHDIRK-ISLDHHEMVAIV 462
++KC+C G+ +T C + + G P S + K + D +E +
Sbjct: 2945 LPVSYKCKCWPGFQLKDDGKT-CVDIDECSSGFPCSQQCINTYGTYKCLCTDGYE-IQPD 3002
Query: 463 NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYN 522
N + D + +D +I K D G+ T++ +Q + ++ +A+D+ Y
Sbjct: 3003 NPNGCKSLSD---EEPFLILAD--HHEIRKISTD-GSNYTLL--KQGL-NNVIAIDFDYR 3053
Query: 523 H--LYWTDTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIE 579
+YW D+ N ++ + N I + P A+A++ + ++W+D + IE
Sbjct: 3054 EEFIYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSD-TEKRIIE 3112
Query: 580 RAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHST 638
+ ++G + + +VS +K+P L+LD +YW+D + I DG+ + +++ T
Sbjct: 3113 VSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVI-ET 3171
Query: 639 EVLRHPFSITT--FEDWVYWTD 658
++ R P ++T +YW D
Sbjct: 3172 KISR-PMALTIDYVNRRLYWAD 3192
Score = 226 bits (553), Expect = 2e-58
Identities = 129/370 (34%), Positives = 167/370 (45%), Gaps = 26/370 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L +++RTC T+S+FRCKT +CIP WKCD DC D SDE P C + CQ
Sbjct: 3304 FYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDCPEFR--CQPG 3360
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
RF+C GLC ++ CD DC D SDE C+ C +F C K +C+P+ C+
Sbjct: 3361 RFQC-GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCT-KNQKCIPVNLRCNG 3418
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXEVKCPTPTCQP 187
DC D DE+ C E +C D F C K CI WV E C TC P
Sbjct: 3419 QDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGP 3478
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
F C + CI W CD DC+D SDE C P+ C +F C + R
Sbjct: 3479 H-EFQCKNNNCIPDHWRCDSQNDCSDNSDEENC--KPQT---CTLKDFLCANGDCVSSRF 3532
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W E +C DQF+C + CIP C+G +DC G DE +C
Sbjct: 3533 WCDGDFDCADGSDERNCE-----TSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSC 3587
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
C R E+ C CI S C+ DC + DE C EC+++ C +
Sbjct: 3588 EPASPTCSSR-EYICASDGCISASLKCNGEYDCADGSDEM--DC-VTECKEDQFRCKNKA 3643
Query: 368 VDTPIGYYCD 377
PI + CD
Sbjct: 3644 HCIPIRWLCD 3653
Score = 217 bits (529), Expect = 2e-55
Identities = 132/394 (33%), Positives = 176/394 (44%), Gaps = 39/394 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+ +C +F+C+ RCIP W CD DC + DE CTA CQ +F C +G C
Sbjct: 883 NHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTA--RTCQVDQFSC-GNGRC 939
Query: 80 IPRSWRCDATADCPDGSDE-HQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
IPR+W CD DC D +DE CE C P +F C K G C+ W CD + DC DGS
Sbjct: 940 IPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVC--KSGRCISSKWHCDSDDDCGDGS 997
Query: 138 DEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQSH 190
DE C +C ++F C +G+CI W E + C +P +
Sbjct: 998 DEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNE 1057
Query: 191 FSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C DG C+ W CDG+ DC DGSDE GC T +R T+F C C+++AWV
Sbjct: 1058 FQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGT--IRLCDHKTKFSCWSTGRCINKAWV 1115
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDE-Y- 305
E + C + C + C + + C+ CNG KDCPDGSDE Y
Sbjct: 1116 CDGDIDCEDQSDE--DDC-DSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGYL 1172
Query: 306 --NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDR--CGENECEKNNG 361
C+ C G G+ VC CP +D C + N+
Sbjct: 1173 CDECSLNNGGCSNHCSVVPGRGI------VC----SCPEGLQLNKDNKTCEIVDYCSNHL 1222
Query: 362 GCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
CSQ C C C +G+KL +D +C +D
Sbjct: 1223 KCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVD 1256
Score = 207 bits (505), Expect = 1e-52
Identities = 123/371 (33%), Positives = 169/371 (45%), Gaps = 37/371 (9%)
Query: 18 SESRTCTS-SEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+++ +C + SEF C G CI CD C D SDE C C+ F+ +
Sbjct: 2505 TKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRS--CRR-GFKPCYN 2561
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP CD DC D SDE C+V C EF C G C+P + C+ N DC+D
Sbjct: 2562 RRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRC--ADGTCIPRSARCNQNIDCADA 2619
Query: 137 SDEKACNETCRSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCPTPT- 184
SDEK CN T + + G C+ W+ E+KCP
Sbjct: 2620 SDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNK 2679
Query: 185 --CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
C+ +++FSC G+CI W CDG DC DG DE C S+ C +F C+ +
Sbjct: 2680 HKCE-ENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDSS------CSWNQFACSAQ-K 2731
Query: 243 CVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDG 301
C+ + W+ E+ +C G +TC D F C+ +C+P C+G +DCPDG
Sbjct: 2732 CISKHWICDGEDDCGDGLDESDSIC-GAITCAADMFSCQGSRACVPRHWLCDGERDCPDG 2790
Query: 302 SDEYN---CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
SDE + C T CD+ F C +CIP VCD DC + DE +CG +C
Sbjct: 2791 SDELSTAGCAPNNT-CDENA-FMCHNKVCIPKQFVCDHDDDCGDGSDE-SPQCGYRQCGT 2847
Query: 359 NNGGCSQ-RCV 368
C+ RC+
Sbjct: 2848 EEFSCADGRCL 2858
Score = 203 bits (495), Expect = 2e-51
Identities = 123/379 (32%), Positives = 201/379 (53%), Gaps = 24/379 (6%)
Query: 383 KLIDNRTCEDIDECA-DPGSCSQICINEKGTFK-CECHTGYARDPRDRTRCKATEGHPSL 440
K+ D + + C + G CSQ+C+ T + C C GY ++R C+ E L
Sbjct: 1825 KVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQ-KNRMSCQGIESF--L 1881
Query: 441 LFARKHDIRKISL---DHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
+++ IR I L D + + ++ T A +D+ I+W+D+ KI +A D+
Sbjct: 1882 MYSVHEGIRGIPLEPSDKMDALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQ 1941
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
T + +I L +G+AVDW+ ++YWTD G N IE++ L G+ R ++I L++PR+
Sbjct: 1942 -TWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQPRS 2000
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++P +G +FWT+WGQ+P I +A +DGS + +VS + WPNG+++D ++YW DA+
Sbjct: 2001 IAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDAR 2060
Query: 618 MNTISSCNYD-GSGRRLILHSTEVLRHPFSITTFEDWVYWTD--WDKTAVYRANKFNGKD 674
+ I + + G R ++L + V FS+ F ++YW+D +V R +K +
Sbjct: 2061 TDKIERIDLETGGNREMVLSGSNV--DMFSVAVFGAYIYWSDRAHANGSVRRGHKNDA-- 2116
Query: 675 VEAITSTHTL-QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
E IT L N + +++ R+ G N CA NG C LCL + NS R +CAC
Sbjct: 2117 TETITMRTGLGVNLKEVKIFNRVRE-KGTNVCARDNGGCKQLCL----YRGNSRR-TCAC 2170
Query: 734 PNGLKLLPDDQMCVEDSKY 752
+G L D C+ Y
Sbjct: 2171 AHGY-LAEDGVTCLRHEGY 2188
Score = 190 bits (462), Expect = 2e-47
Identities = 119/378 (31%), Positives = 187/378 (49%), Gaps = 30/378 (7%)
Query: 385 IDNRTCEDIDECADPGSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
+ + CE +D PG CS IC+ T C C TG+ R+ CK + L +
Sbjct: 470 VRSHACE-VDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRS-CKRPKNELFLFY 527
Query: 443 ARKHD--IRKISLDHH---EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
+ +R + L+ E + + + + ALD+ T I+++D I + ID
Sbjct: 528 GKGRPGIVRGMDLNTKIADEYMIPIENLVNPRALDFHAETNYIYFADTTSFLIGRQKID- 586
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDRLEE 554
GT+R ++ + L +G+AVDW+ N+LYWT+ GH I ++ L+ RK L+ +
Sbjct: 587 GTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSH 646
Query: 555 PRAIALNPLEGWMFWTDWGQ------VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
PR I ++P+ GWM+WTDW + V +IE+A MDG +R V+ + WPNGLTLD
Sbjct: 647 PRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHT 706
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+YW DA + I +G+ R+ I++S L HPF ++ ++V+WTD+ ++++ +
Sbjct: 707 NTLYWCDAYYDHIEKVFLNGTHRK-IVYSGRELNHPFGLSHHGNYVFWTDYMNGSIFQLD 765
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPR 728
E H + +Y P R+ G N C NG CS LCL P R
Sbjct: 766 LITS---EVTLLRHERPPLFGLQIYDP-RKQQGDNMCRVNNGGCSTLCLAIP-----GGR 816
Query: 729 VSCACPNGLKLLPDDQMC 746
V CAC + L + C
Sbjct: 817 V-CACADNQLLDENGTTC 833
Score = 151 bits (366), Expect = 9e-36
Identities = 109/373 (29%), Positives = 182/373 (48%), Gaps = 36/373 (9%)
Query: 396 CA-DPGSCSQICINEKGTFK-CECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISL 453
CA D G C Q+C+ + + C C GY + D C EG+ LL++ + ++ I L
Sbjct: 2147 CARDNGGCKQLCLYRGNSRRTCACAHGYLAE--DGVTCLRHEGY--LLYSGRTILKSIHL 2202
Query: 454 -DHHEMVAIVNDTKS--------ATALDYVFR---TGMIFWSDVNDEKIYKAPIDEGTQR 501
D + + + ++ A A DY R T IF+SD + I D R
Sbjct: 2203 SDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIK-DNWEDR 2261
Query: 502 TVVIGEQLITSDGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEP 555
V++ E + + +GLA ++ LYWT T H + + ++ + P
Sbjct: 2262 QVIV-ENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHP 2320
Query: 556 RAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV 614
+AL+ + MFWT+W Q P I R+ + G + +VS D+ PNGLT+D +++Y+
Sbjct: 2321 HVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFS 2380
Query: 615 DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKD 674
D + I C YDGS R +I+ S S+ ++++++W+DW + A+ R+NK+ G D
Sbjct: 2381 DGSLGKIERCEYDGSQRHVIVKSGPGTF--LSLAVYDNYIFWSDWGRRAILRSNKYTGGD 2438
Query: 675 VEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACP 734
+ + S Q +I V + + ++ CA +NG C LCL P + RV+C+C
Sbjct: 2439 TKILRSDIPHQPMGIIAVANDTNSCE-LSPCALLNGGCHDLCLLTP-----NGRVNCSC- 2491
Query: 735 NGLKLLPDDQMCV 747
G ++L +D CV
Sbjct: 2492 RGDRILLEDNRCV 2504
Score = 148 bits (359), Expect = 6e-35
Identities = 106/374 (28%), Positives = 176/374 (47%), Gaps = 28/374 (7%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEM 458
G CS +C IN + C C + D+ C E LL+AR+ +IR + +D+
Sbjct: 1538 GPCSHMCLINHNRSAACAC-PHLMKLSSDKKTCY--EMKKFLLYARRSEIRGVDIDNPYF 1594
Query: 459 VAI----VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
I V D T +D+ ++W+D+ + I +A I+ GT VI + + G
Sbjct: 1595 NFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFIN-GTGLETVISRDIQSIRG 1653
Query: 515 LAVDWVYNHLYW--TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +LYW ++ I ++ L G+++ +I +++P+ +A +P+ G ++WTD
Sbjct: 1654 LAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHG-IDKPQCLAAHPVRGKLYWTDG 1712
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+ S I+ + K P GL++D V ++YW+ + TI+ CN DG
Sbjct: 1713 NT---INMANMDGSN-SKILFQNQKEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLE 1768
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH- 691
+I E L ++T + ++W D + + +K +G++ + + + V+H
Sbjct: 1769 VIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRN----KTSGVVHM 1824
Query: 692 -VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
VY Q G N C NG CS LCLP + +C C G L + C
Sbjct: 1825 KVYDKEAQ-QGSNSCQLNNGGCSQLCLPT-----SETTRTCMCTVGYYLQKNRMSCQGIE 1878
Query: 751 KYHFLPFYNNFRSI 764
+ + R I
Sbjct: 1879 SFLMYSVHEGIRGI 1892
Score = 133 bits (321), Expect = 3e-30
Identities = 107/380 (28%), Positives = 140/380 (36%), Gaps = 32/380 (8%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEK-DCSDSSDE---DPTVCTATKMVCQEY-RFE 72
+++ +C S G C L N + +CS D + C C Y FE
Sbjct: 2458 NDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFE 2517
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDEH--QCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C +G CI CD C D SDE CE +C C + C+P +CD
Sbjct: 2518 C-GNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNR--RCIPHGKLCDGE 2574
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTC---- 185
DC D SDE C TC + EF C +G CI E C C
Sbjct: 2575 NDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFY 2634
Query: 186 ----QPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDR 240
+ C + C+ W CDG DC D SDE+ C K + C F C
Sbjct: 2635 KLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHK--CEENYFSCPSG 2692
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPD 300
C+ W+ E + +C +QF C CI C+G DC D
Sbjct: 2693 -RCILNTWICDGQKDCEDGRDE----FHCDSSCSWNQFACSAQKCISKHWICDGEDDCGD 2747
Query: 301 GSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDE-PRDRCG-ENECE 357
G DE + C F C G C+P +CD DCP+ DE C N C+
Sbjct: 2748 GLDESDSICGAITC-AADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCD 2806
Query: 358 KNNGGCSQRCVDTPIGYYCD 377
+N C + V P + CD
Sbjct: 2807 ENAFMCHNK-VCIPKQFVCD 2825
Score = 119 bits (287), Expect = 3e-26
Identities = 80/263 (30%), Positives = 102/263 (38%), Gaps = 18/263 (6%)
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTP 183
+ D+N + +A C++ EF C N CIQ RW E V C
Sbjct: 825 LLDENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNH 884
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C P F C + +CI W CDG DC DE T + C +F C + C
Sbjct: 885 SC-PDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTART---CQVDQFSCGNG-RC 939
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ RAW+ E + C L QF CK CI +C+ DC DGSD
Sbjct: 940 IPRAWLCDREDDCGDQTDE-MASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSD 998
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE------CE 357
E C C +F C G CIP CD DC +F DE + C + E C
Sbjct: 999 EVGCVHS---CFD-NQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCN 1054
Query: 358 KNNGGCSQRCVDTPIGYYCDCEK 380
N C P + CD EK
Sbjct: 1055 GNEFQCHPDGNCVPDLWRCDGEK 1077
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/168 (30%), Positives = 78/168 (46%), Gaps = 11/168 (6%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELC--RGNVTCRLDQFQC-KDHSCI 286
C EF C+D +TCV ++W+ E+L+ C + C L+ C + C+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCV 91
Query: 287 PGALYCNGVKDCPDGSDE-YNCTRQKTICDK-RTEFDCGGGMCIPLSKVCDKHVDCPNFE 344
+ CNGV DCPDG DE +C + C + ++ C + S C D
Sbjct: 92 HLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKC---TMVRNSTRCYCE-DGFEIT 147
Query: 345 DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
++ R ++EC G CSQ C +T Y C C +GY + DNR+C+
Sbjct: 148 EDGRSCKDQDECAV-YGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCK 194
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/152 (29%), Positives = 63/152 (41%), Gaps = 18/152 (11%)
Query: 19 ESRTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVC-TATKMVCQEYRFECLSD 76
+ + C EF C C+ SW CD + DC D SDE C ++ C CL
Sbjct: 28 DQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGT 87
Query: 77 GLCIPRSWRCDATADCPDGSDEH-QCEVEACGPEEFTCRGK--------PGECVPLTWMC 127
C+ S C+ DCPDG DE C+ ++ C+ K C +
Sbjct: 88 NKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEIT 147
Query: 128 DDNPDCSDGSDEKA----CNETCRS--DEFTC 153
+D C D DE A C++TCR+ +TC
Sbjct: 148 EDGRSCKD-QDECAVYGTCSQTCRNTHGSYTC 178
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/106 (34%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
Query: 63 KMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE--HQC--EVE-ACGPEEFTCRGKP 117
+ +C F C C+ +SW CD DCPD SDE C EVE C C G
Sbjct: 29 QQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLG-T 87
Query: 118 GECVPLTWMCDDNPDCSDGSDEKA-CNETCRSDEFTCGNGKCIQMR 162
+CV L+ +C+ DC DG DE C E + + KC +R
Sbjct: 88 NKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVR 133
Score = 53.6 bits (123), Expect = 3e-06
Identities = 73/316 (23%), Positives = 118/316 (37%), Gaps = 25/316 (7%)
Query: 352 GENECEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNRTC-EDIDECADPGSCSQICINE 409
G N C ++NGGC Q C+ C C GY D TC G I+
Sbjct: 2143 GTNVCARDNGGCKQLCLYRGNSRRTCACAHGYLAEDGVTCLRHEGYLLYSGRTILKSIHL 2202
Query: 410 KGTFKCECHTGYARDPRDRTRCKA--------TEGHPSLLFARKH--DIRKISLDHHEMV 459
+PR A +G + ++ H +I+ I + +
Sbjct: 2203 SDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQ 2262
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG----- 514
IV + S L Y ++W+ I + +D+ T+ E +IT
Sbjct: 2263 VIVENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQ-TRPGAFDREAVITMSEDDHPH 2321
Query: 515 -LAVDWVYNHLYWTDTGHNH--IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
LA+D N ++WT+ H I S L G ++++ + P + ++ ++++D
Sbjct: 2322 VLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSD 2381
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
G + KIER DGS R IV L+L + ++W D I N G
Sbjct: 2382 -GSLGKIERCEYDGSQRHVIVKSGP--GTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGD 2438
Query: 632 RLILHSTEVLRHPFSI 647
IL S ++ P I
Sbjct: 2439 TKILRS-DIPHQPMGI 2453
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 303 DEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGG 362
++ C + + C+ +EF+CG G CI CD C + DE C C +
Sbjct: 2499 EDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKP 2558
Query: 363 C-SQRCVDTPIGYYC----DCEKGYKLIDNR--TCEDID-ECADPGSC 402
C ++RC+ P G C DC +D + TC ++ CAD G+C
Sbjct: 2559 CYNRRCI--PHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD-GTC 2603
Score = 45.6 bits (103), Expect = 7e-04
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 346 EPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPG-SCS 403
+PR + G+N C NNGGCS C+ P G C C L +N T C +PG +
Sbjct: 788 DPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGT-----TCTFNPGEALP 842
Query: 404 QICINEKGTFKCE 416
IC + G F+C+
Sbjct: 843 HIC--KAGEFRCK 853
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/62 (38%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 185 CQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C P F C D C+S W CDGD DC D SDE +V C C C
Sbjct: 32 CDP-GEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKC 90
Query: 244 VH 245
VH
Sbjct: 91 VH 92
Score = 42.7 bits (96), Expect = 0.005
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 352 GENECEKNNGGCSQRCVDT-PIGYYCDCEKGYKLIDNR-TCEDID 394
G N C+ NNGGCSQ C+ T C C GY L NR +C+ I+
Sbjct: 1834 GSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGIE 1878
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC-------INEKGTFKC 415
C C+ P G C C +G LI N TC D D D SC C +NEKG +C
Sbjct: 4181 CEFLCLLNPSGATCVCPEGKYLI-NGTCND-DSLLDD-SCKLTCENGGRCILNEKGDLRC 4237
Query: 416 ECHTGYARDPRDRTRC 431
C Y+ + + C
Sbjct: 4238 HCWPSYSGERCEVNHC 4253
>Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor 2
906 protein.
Length = 699
Score = 493 bits (1216), Expect = e-139
Identities = 235/581 (40%), Positives = 339/581 (58%), Gaps = 26/581 (4%)
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDR 240
P C+ + F C + +CI + W CD D DC D SDE C PK C ++F C D
Sbjct: 43 PAKECE-KDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDC---PK--KTCADSDFTC-DN 95
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQC--KDHSCIPGALYCNGVKDC 298
C+H W E+ C V C ++ C H C+P + C+G KDC
Sbjct: 96 GHCIHERWKCDGEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCVPASWRCDGEKDC 154
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
G+DE C C + EF CG G C+ K C++ DCP+ DE G NEC
Sbjct: 155 EGGADEAGCATSLGTC-RGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLH 213
Query: 359 NNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECH 418
NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+N KG FKCEC+
Sbjct: 214 NNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECY 273
Query: 419 TGYARDPRDRTRCKATEGH-PSLLFARKHDI--RKISLDHHEMVAIVNDTKSATALDYVF 475
G D + CKA G PSL+F + R + ++ ++ ++ K+ ALD
Sbjct: 274 PGCEMDLLTKN-CKAAAGKSPSLIFTNRTSAEDRPVKRNYSRLIPML---KNVVALDVEV 329
Query: 476 RTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
T I+W D++ KIY A +D+ + +R V+I EQL + +GLAVDWV+ H+YWTD+G+
Sbjct: 330 ATNRIYWCDLSYRKIYSAYMDKASDPKEREVLIDEQLHSPEGLAVDWVHKHIYWTDSGNK 389
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G++G R T+V
Sbjct: 390 TISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLV 449
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L HPF I FED
Sbjct: 450 SDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFED 509
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHC---AAVN 709
V+WTD + A++ AN+ NG ++ + L NP I ++H +QP + C N
Sbjct: 510 KVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPDACELSVQPN 567
Query: 710 GHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
G C +LCLPAP+ +SP+ +CACP+ + L PD + C D+
Sbjct: 568 GGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRDA 608
Score = 140 bits (340), Expect = 1e-32
Identities = 60/145 (41%), Positives = 80/145 (55%), Gaps = 10/145 (6%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKACNE---TCRSDEFTCGNGKCI 159
DE C TCR DEF CG+G C+
Sbjct: 159 DEAGCATSLGTCRGDEFQCGDGTCV 183
Score = 114 bits (275), Expect = 1e-24
Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 9/141 (6%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFEC-LSDGLC 79
+TC S+F C G CI WKCD E++C D SDE C TK VC + C + C
Sbjct: 84 KTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATC--TKQVCPAEKLSCGPTSHKC 141
Query: 80 IPRSWRCDATADCPDGSDEHQC--EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
+P SWRCD DC G+DE C + C +EF C G CV C+ DC DGS
Sbjct: 142 VPASWRCDGEKDCEGGADEAGCATSLGTCRGDEFQC--GDGTCVLAIKHCNQEQDCPDGS 199
Query: 138 DEKACNETCRSDEFTCGNGKC 158
DE C + +E NG C
Sbjct: 200 DEAGCLQGL--NECLHNNGGC 218
Score = 110 bits (265), Expect = 2e-23
Identities = 56/150 (37%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 100 QCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC-NETCRSDEFTCGNGKC 158
Q + C ++F CR + C+P W CD++ DC D SDE C +TC +FTC NG C
Sbjct: 41 QGPAKECEKDQFQCRNE--RCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHC 98
Query: 159 IQMRWVXXXXXX--XXXXXXEVKCPTPTCQPQSHFSC--TDGQCISAWWHCDGDVDCADG 214
I RW E C C P SC T +C+ A W CDG+ DC G
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVC-PAEKLSCGPTSHKCVPASWRCDGEKDCEGG 157
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCV 244
+DE GC ++ C EF+C D TCV
Sbjct: 158 ADEAGCATS---LGTCRGDEFQCGDG-TCV 183
>U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein.
Length = 1751
Score = 477 bits (1177), Expect = e-134
Identities = 266/750 (35%), Positives = 376/750 (50%), Gaps = 56/750 (7%)
Query: 21 RTCTSS-EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R C ++ EF C RCIP + C+ +C D++ D C CQ +C + +C
Sbjct: 74 RDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCP--DRTCQSGYPKCHNSNIC 131
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTW-MCDDNPDCSDG 136
IPR + CD DC D SDE+ C C EF C G C+P T+ +CD DC D
Sbjct: 132 IPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS--GRCIPQTFGICDQETDCFDA 189
Query: 137 SDE-KACNE---TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK---CPTPTCQPQS 189
SDE +C TC SDEF C G+CI W+ E K C C S
Sbjct: 190 SDEPSSCGHSERTCLSDEFKCDGGRCIPNEWICDGDNDCGDMSDEDKRHQCQNQNCS-DS 248
Query: 190 HFSCT-----DGQCISAWWHCDGDVDCADGSDEV-GCVSTPKVRSPCISTEFECNDRITC 243
F C D +CI W DGDVDC DG DE+ C R C EF C + C
Sbjct: 249 EFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCT-----RRTCSENEFTCGYGL-C 302
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ + + E L + TC+ +QF C++ CI C+ DC DGSD
Sbjct: 303 IPKIFRCDRHNDCGDYSDERGCLYQ---TCQQNQFTCQNGRCISKTFVCDEDNDCGDGSD 359
Query: 304 E--YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNN 360
E + C + C EF C G CI + K+C+ DC + DE CG NEC + +
Sbjct: 360 ELMHLCHTPEPTCPPH-EFKCDNGRCIEMMKLCNHLDDCLDNSDEKG--CGINECHDPSI 416
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGTFKCECH 418
GC C DT +YC C GYKL+ D RTC DIDEC + P CSQ C N G++ C+C
Sbjct: 417 SGCDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCA 476
Query: 419 TGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTG 478
GY R+P +T + + P L+F+ ++ +R +++D + I+ + ALD+
Sbjct: 477 PGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEK 536
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
++W D + I + +++ T + +I +L ++ LAVDWV LYW D + + +SD
Sbjct: 537 RLYWIDTQRQVIERMFLNK-TNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSD 595
Query: 539 LQGNMRKILIRDRLE--------EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRST 590
L G R++L + ++ PR +AL+P G+++W DWG I R GMDG+++S
Sbjct: 596 LNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSV 655
Query: 591 IVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
I+S ++WPNG+T+D +YW DA + I + +G R + L HPF+IT F
Sbjct: 656 IISTKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG--ALPHPFAITIF 713
Query: 651 EDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNG 710
ED +YWTDW+ V + NK++G + + T +T P IHVYHPYRQP N C NG
Sbjct: 714 EDTIYWTDWNTRTVEKGNKYDGSNRQ--TLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNG 771
Query: 711 HCSHLCLPAPRFGPNSPRVSCACPNGLKLL 740
CSHLCL P +C CP+ + L
Sbjct: 772 GCSHLCL----IKPGGKGFTCECPDDFRTL 797
Score = 457 bits (1127), Expect = e-128
Identities = 268/748 (35%), Positives = 370/748 (49%), Gaps = 53/748 (7%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGL 78
SRTC +FRC GRCIP +WKCD + DC D SDE C ++ +C + F C ++
Sbjct: 929 SRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYR 988
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP+ C+ DC D SDE CE C P +F C K C+PL W CD DC D S
Sbjct: 989 CIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRC--KNHHCIPLRWKCDGQNDCGDNS 1046
Query: 138 DEKAC-NETCRSDEFTCGNGKCIQMRWV-XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
DE+ C C EF C N +CI RW+ E C TC P+ +F CT
Sbjct: 1047 DEENCAPRECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEMRTCHPE-YFQCTS 1105
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G + + CDG DC D SDE C + + C +T FEC + + C+ W
Sbjct: 1106 GHRVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHV-CIPPYWKCDGDDD 1164
Query: 256 XXXXXXEALELCRGNVTCRL-DQFQCKDHSCIPGALYCNGVKDCPDGSD--EYNCTRQKT 312
E L LC +V C ++F+C ++ CI CNGV DC DG+D E +C +
Sbjct: 1165 CGDGSDEELHLCL-DVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTP 1223
Query: 313 ICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG-ENECEKNNGGCSQRCVD-T 370
E+ CG G CIP VCD DC ++ DE G E C +N C Q C
Sbjct: 1224 KPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENI--CEQNCTQLN 1281
Query: 371 PIGYYCDCEKGYK--LIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY-ARDPRD 427
G+ C C G++ + D +C DI+EC G+C Q C N KG+++C C G+ + R
Sbjct: 1282 EGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRP 1341
Query: 428 RTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVF---RTGM-IFWS 483
RC A P LL IRK +L + D + A+DY + G+ + +
Sbjct: 1342 GKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPEDIGLSVVYY 1401
Query: 484 DVNDE--------KIYKAPIDEG----TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH 531
V E + Y + G Q + + ++ DG+AVDWV H+YW+D +
Sbjct: 1402 TVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKN 1461
Query: 532 NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTI 591
IE++ L G RK LI L++P AIA+NP G MFWTDWG+ PK+E A M+G + +
Sbjct: 1462 KRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKLESAWMNGEDPNIL 1521
Query: 592 VSYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTF 650
V D+ WP GL++D L R+YW D K + I + YDG+ RR+I + E + +P+S+ F
Sbjct: 1522 VFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVI--AKEAM-NPYSLDIF 1578
Query: 651 EDWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVIHVYHPYRQPDGV-NHCAAV 708
ED +YW +K V++ NKF GK + + L + ++H R V N C +
Sbjct: 1579 EDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---VRIFHQLRYNKSVPNLCKQI 1635
Query: 709 NGHCSHLCLPAPRFGPNSPRVSCACPNG 736
CSHLCL P SCACP G
Sbjct: 1636 ---CSHLCLLRP------GGYSCACPQG 1654
Score = 240 bits (588), Expect = 1e-62
Identities = 197/670 (29%), Positives = 297/670 (44%), Gaps = 99/670 (14%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWK-CDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
+ + TC+SSEF+C +GRCIP ++ CD E DC D+SDE P+ C ++ C F+C
Sbjct: 154 YCTTHTCSSSEFQCASGRCIPQTFGICDQETDCFDASDE-PSSCGHSERTCLSDEFKC-D 211
Query: 76 DGLCIPRSWRCDATADCPDGSDE---HQCEVEACGPEEFTC---RGKPGECVPLTWMCDD 129
G CIP W CD DC D SDE HQC+ + C EF C R C+P +W D
Sbjct: 212 GGRCIPNEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDG 271
Query: 130 NPDCSDGSDE--KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQP 187
+ DC+DG DE TC +EFTCG G CI + E C TCQ
Sbjct: 272 DVDCTDGHDEIQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQ- 330
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFECNDRITCVHR 246
Q+ F+C +G+CIS + CD D DC DGSDE + TP+ C EF+C D C+
Sbjct: 331 QNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPE--PTCPPHEFKC-DNGRCI-- 385
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS---D 303
E ++LC LD C D+S G G+ +C D S
Sbjct: 386 ---------------EMMKLCN-----HLD--DCLDNSDEKGC----GINECHDPSISGC 419
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGC 363
++NCT D T F C C P K+ C + + EC + C
Sbjct: 420 DHNCT------DTLTSFYCS---CRPGYKLMSDKRTCVDID----------ECTEMPFVC 460
Query: 364 SQRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY- 421
SQ+C + Y C C GY + D +TC + +P + + + + GY
Sbjct: 461 SQKCENVIGSYICKCAPGYLREPDGKTCRQ-NSNIEP----YLIFSNRYYLRNLTIDGYF 515
Query: 422 ---ARDPRDRTRCKATEGHPSLLF---ARKHDIRKISLDHHEMVAIVNDTKSAT---ALD 472
+ D + L+ ++ I ++ L+ I+N A A+D
Sbjct: 516 YSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVD 575
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTV----VIGEQLITSD---GLAVDWVYNHLY 525
+V R ++W D + ++ + ++ G +R + V D GLA+ Y +LY
Sbjct: 576 WVSR--KLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLY 633
Query: 526 WTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMD 584
W D GH +I + G + ++I +LE P I ++ ++W D + IE + ++
Sbjct: 634 WADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYWAD-AHLGYIEYSDLE 692
Query: 585 GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEVLRH 643
G HR T+ YD P+ + + +YW D T+ N YDGS R+ ++++T
Sbjct: 693 GHHRHTV--YDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTT---HR 747
Query: 644 PFSITTFEDW 653
PF I + +
Sbjct: 748 PFDIHVYHPY 757
Score = 209 bits (510), Expect = 3e-53
Identities = 143/434 (32%), Positives = 192/434 (44%), Gaps = 32/434 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLS 75
L E+ C S+E++C RCIP SW+CD+ DC D+SDED + C + C+ +F C +
Sbjct: 884 LLCENHHCDSNEWQCANKRCIPESWQCDSFNDCEDNSDEDSSHCAS--RTCRPGQFRC-A 940
Query: 76 DGLCIPRSWRCDATADCPDGSDE--HQCEVEA--CGP-EEFTCRGKPGECVPLTWMCDDN 130
+G CIP++W+CD DC D SDE +C A C EF+C+ C+P +C+
Sbjct: 941 NGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTN-YRCIPKWAVCNGV 999
Query: 131 PDCSDGSDEKACNE-TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
DC D SDE+ C E TC +F C N CI +RW E C C +
Sbjct: 1000 DDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWKCDGQNDCGDNSDEENCAPREC-TE 1058
Query: 189 SHFSCTDGQCISAWWHCDGDVDC-ADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
S F C + QCI + W CD D D SDE C ++R+ C F+C VH
Sbjct: 1059 SEFRCVNQQCIPSRWICDHYNDLWGDNSDERDC----EMRT-CHPEYFQCTSGHR-VHSE 1112
Query: 248 WVXXXXXXXXXXXXEALELCR--GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
EA R C+ F+CK+H CIP C+G DC DGSDE
Sbjct: 1113 LKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEE 1172
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE---NECEKNNGG 362
C+ F C CI +VC+ DC + DE + C + C +
Sbjct: 1173 LHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYK 1232
Query: 363 CSQ-RCVDTPIGYYC-DCEKGYKLIDNRTCEDIDE--CADPGSCSQICIN-EKGTFKCEC 417
C C+ P C D + D C E CA+ C Q C +G F C C
Sbjct: 1233 CGNGHCI--PHDNVCDDADDCGDWSDELGCNKGKERTCAE-NICEQNCTQLNEGGFICSC 1289
Query: 418 HTGYARDPRDRTRC 431
G+ + DRT C
Sbjct: 1290 TAGFETNVFDRTSC 1303
Score = 208 bits (507), Expect = 7e-53
Identities = 183/671 (27%), Positives = 265/671 (39%), Gaps = 60/671 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV---CTATKMVCQEYRFECLSDGL 78
TC+ + F C GRC+ S++CD DC D SDE + C AT F C ++
Sbjct: 36 TCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDETGCLFRDCNATT------EFMC-NNRR 88
Query: 79 CIPRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIPR + C+ +C D SDE C C C C+P ++CD + DC D
Sbjct: 89 CIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYPKCHNS-NICIPRVYLCDGDNDCGDN 147
Query: 137 SDEK---ACNETCRSDEFTCGNGKCIQMRW--VXXXXXXXXXXXXEVKC--PTPTCQPQS 189
SDE TC S EF C +G+CI + C TC
Sbjct: 148 SDENPTYCTTHTCSSSEFQCASGRCIPQTFGICDQETDCFDASDEPSSCGHSERTCL-SD 206
Query: 190 HFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-NDR---ITCVH 245
F C G+CI W CDGD DC D SDE C +EF C NDR C+
Sbjct: 207 EFKCDGGRCIPNEWICDGDNDCGDMSDEDKRHQCQ--NQNCSDSEFPCVNDRPPDRRCIP 264
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
++W E R TC ++F C CIP C+ DC D SDE
Sbjct: 265 QSWPPDGDVDCTDGHDEIQNCTRR--TCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDER 322
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRC--GENECEKNNGGC 363
C Q C ++ +F C G CI + VCD+ DC + DE C E C + C
Sbjct: 323 GCLYQ--TC-QQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKC 379
Query: 364 SQ-RCVDTP--IGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFKCECH 418
RC++ + DC D + C I+EC DP C C + +F C C
Sbjct: 380 DNGRCIEMMKLCNHLDDCLDN---SDEKGC-GINECHDPSISGCDHNCTDTLTSFYCSCR 435
Query: 419 TGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFR 476
GY + D+ C + + F + + A + + T
Sbjct: 436 PGY-KLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQNSNI 494
Query: 477 TGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIEL 536
+ +S N + ID G ++++ E L L D V LYW DT IE
Sbjct: 495 EPYLIFS--NRYYLRNLTID-GYFYSLIL-EGLDNVVALDFDRVEKRLYWIDTQRQVIER 550
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDV 596
L ++ +I RL ++A++ + ++W D ++ + + ++G HR + + V
Sbjct: 551 MFLNKTNKETIINHRLPAAESLAVDWVSRKLYWLD-ARLDGLFVSDLNGGHRRMLAQHCV 609
Query: 597 KW--------PNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSI 647
P GL L +YW D I DG+ + +I+ + + +I
Sbjct: 610 DANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITI 669
Query: 648 TTFEDWVYWTD 658
D +YW D
Sbjct: 670 DYTNDLLYWAD 680
Score = 196 bits (478), Expect = 2e-49
Identities = 128/365 (35%), Positives = 164/365 (44%), Gaps = 31/365 (8%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
F C GRCI WKCDN+ C D SDE +VC C F C ++G C+ S+RCD
Sbjct: 1 FTCSNGRCISEEWKCDNDNGCGDGSDEMESVCAL--HTCSPTAFTC-ANGRCVQYSYRCD 57
Query: 88 ATADCPDGSDEHQCEVEAC-GPEEFTCRGKPGECVPLTWMCDDNPDCSDG--SDEKAC-N 143
DC DGSDE C C EF C + C+P ++C+ +C D SDEK C +
Sbjct: 58 YYNDCGDGSDETGCLFRDCNATTEFMCNNR--RCIPREFICNGVDNCHDNNTSDEKNCPD 115
Query: 144 ETCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTDGQCI- 199
TC+S C N CI ++ E C T TC S F C G+CI
Sbjct: 116 RTCQSGYPKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCS-SSEFQCASGRCIP 174
Query: 200 SAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXX 259
+ CD + DC D SDE S C+S EF+C D C+ W+
Sbjct: 175 QTFGICDQETDCFDASDEPS--SCGHSERTCLSDEFKC-DGGRCIPNEWICDGDNDCGDM 231
Query: 260 XXEALELCRGNVTCRLDQFQC-----KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTI 313
E N C +F C D CIP + +G DC DG DE NCTR+
Sbjct: 232 SDEDKRHQCQNQNCSDSEFPCVNDRPPDRRCIPQSWPPDGDVDCTDGHDEIQNCTRR--T 289
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPI 372
C + EF CG G+CIP CD+H DC ++ DE C C++N C RC+
Sbjct: 290 CSE-NEFTCGYGLCIPKIFRCDRHNDCGDYSDE--RGCLYQTCQQNQFTCQNGRCISKT- 345
Query: 373 GYYCD 377
+ CD
Sbjct: 346 -FVCD 349
Score = 180 bits (438), Expect = 2e-44
Identities = 113/336 (33%), Positives = 153/336 (45%), Gaps = 29/336 (8%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C+S++F C +CIP+ WKCD +KDCSD SDE + + C+ +F+C SDG C
Sbjct: 809 CSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDE---LALCPQRFCRLGQFQC-SDGNCTS 864
Query: 82 RSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
C+A +CPDGSDE + CE C E+ C K C+P +W CD DC D SDE
Sbjct: 865 PQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANK--RCIPESWQCDSFNDCEDNSDE 922
Query: 140 KA---CNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPT--CQPQSHFS 192
+ + TCR +F C NG+CI W E +C + C + FS
Sbjct: 923 DSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFS 982
Query: 193 C-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C T+ +CI W C+G DC D SDE GC + R+ +F C + C+ W
Sbjct: 983 CKTNYRCIPKWAVCNGVDDCRDNSDEQGC----EERTCHPVGDFRCKNH-HCIPLRWKCD 1037
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDC-PDGSDEYNCTRQ 310
E E C C +F+C + CIP C+ D D SDE +C +
Sbjct: 1038 GQNDCGDNSDE--ENCAPR-ECTESEFRCVNQQCIPSRWICDHYNDLWGDNSDERDC--E 1092
Query: 311 KTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
C F C G + CD DC + DE
Sbjct: 1093 MRTCHPE-YFQCTSGHRVHSELKCDGSADCLDASDE 1127
Score = 165 bits (400), Expect = 7e-40
Identities = 108/343 (31%), Positives = 149/343 (43%), Gaps = 36/343 (10%)
Query: 65 VCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGECVPL 123
+C +F C ++ CIP W+CD DC DGSDE C C +F C G C
Sbjct: 808 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQC--SDGNCTSP 865
Query: 124 TWMCDDNPDCSDGSDEK--AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--V 178
+C+ + +C DGSDE C N C S+E+ C N +CI W E
Sbjct: 866 QTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDSFNDCEDNSDEDSS 925
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCIS-TEF 235
C + TC+P F C +G+CI W CD D DC D SDE C+S+ + C + TEF
Sbjct: 926 HCASRTCRP-GQFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHL---CDNFTEF 981
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C C+ + V E + C + F+CK+H CIP C+G
Sbjct: 982 SCKTNYRCIPKWAVCNGVDDCRDNSDE--QGCEERTCHPVGDFRCKNHHCIPLRWKCDGQ 1039
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE 355
DC D SDE NC ++ C + +EF C CIP +CD ++ D D E +
Sbjct: 1040 NDCGDNSDEENCAPRE--CTE-SEFRCVNQQCIPSRWICD------HYNDLWGDNSDERD 1090
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECAD 398
CE C Y C G+++ C+ +C D
Sbjct: 1091 CEMRT--CHPE--------YFQCTSGHRVHSELKCDGSADCLD 1123
Score = 118 bits (283), Expect = 1e-25
Identities = 99/339 (29%), Positives = 136/339 (40%), Gaps = 30/339 (8%)
Query: 113 CRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG-KCIQMRWVXXXXXXX 171
C KPG T C D+ S C C S +F C N KCI + W
Sbjct: 777 CLIKPGG-KGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDC 835
Query: 172 XXXXXEVK-CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPC 230
E+ CP C+ F C+DG C S C+ +C DGSDE + C
Sbjct: 836 SDGSDELALCPQRFCR-LGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCE---NHHC 891
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGAL 290
S E++C ++ C+ +W E C TCR QF+C + CIP A
Sbjct: 892 DSNEWQCANK-RCIPESWQCDSFNDCEDNSDEDSSHCASR-TCRPGQFRCANGRCIPQAW 949
Query: 291 YCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGG-MCIPLSKVCDKHVDCPNFEDEP 347
C+ DC D SDE C +CD TEF C CIP VC+ DC + DE
Sbjct: 950 KCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE- 1008
Query: 348 RDRCGENECEK-NNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQI 405
C E C + C + C+ P+ + CD + DN D + CA P C++
Sbjct: 1009 -QGCEERTCHPVGDFRCKNHHCI--PLRWKCDGQNDCG--DN---SDEENCA-PRECTES 1059
Query: 406 ---CINEK---GTFKCECHTGYARDPRDRTRCKATEGHP 438
C+N++ + C+ + D D C+ HP
Sbjct: 1060 EFRCVNQQCIPSRWICDHYNDLWGDNSDERDCEMRTCHP 1098
>AK054663-1|BAB70786.1| 820|Homo sapiens umor (LRPDIT) mRNA.
protein.
Length = 820
Score = 461 bits (1136), Expect = e-129
Identities = 256/714 (35%), Positives = 370/714 (51%), Gaps = 46/714 (6%)
Query: 63 KMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVP 122
+ +C F C C+ +SW CD DCPD SDE C ++F+C G C+P
Sbjct: 67 QQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTSRTCQVDQFSCGN--GRCIP 124
Query: 123 LTWMCDDNPDCSDGSDEKACNE--TCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK 179
W+CD DC D +DE A E TC +F C +G+CI +W EV
Sbjct: 125 RAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVG 184
Query: 180 CPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSP--CISTEF 235
C +C + F C+ G+CI W CDGD DC D SDE + C ++ SP C EF
Sbjct: 185 C-VHSCF-DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKE-EIHSPAGCNGNEF 241
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNV-TC-RLDQFQC-KDHSCIPGALYC 292
+C+ CV W E + C G + +C +F C CI A C
Sbjct: 242 QCHPDGNCVPDLWRCDGEKDCEDGSDE--KGCNGTIRSCDHKTKFSCWSTGRCINKAWVC 299
Query: 293 NGVKDCPDGSDEYNCTRQKTICDKRTEFDCGG--GMCIPLSKVCDKHVDCPNFEDEPRDR 350
+G DC D SDE +C +C + C +C+ K+C+ DCP+ DE
Sbjct: 300 DGDIDCEDQSDEDDC--DSFLCGP-PKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGY-L 355
Query: 351 CGENECEKNNGGCSQRCVDTP-IGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICIN 408
C +EC NNGGCS C P G C C +G +L DN+TCE +D C++ CSQ+C
Sbjct: 356 C--DECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVCEQ 413
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPS-LLFARKHDIRKISLDHHEMVAIVNDTKS 467
K T KC C+ G+ D D C + + + ++F+ +H+IR+I L + +V ++
Sbjct: 414 HKHTVKCSCYEGWKLDV-DGESCTSVDPFEAFIIFSIRHEIRRIDLHKRDYSLLVPGLRN 472
Query: 468 ATALDYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGEQLITSDGLAVDWVYNHL 524
ALD+ F +++W+DV +++IY+ + E + VV+ L T +GL VDW+ ++
Sbjct: 473 TIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNI 532
Query: 525 YWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW-GQVPKIERAGM 583
YW D+ + IE++ L G++R LI +E PRAIAL+P G +FWTDW P+IE A M
Sbjct: 533 YWIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASM 592
Query: 584 DGSHRSTIVSYDVK---WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEV 640
G+ R TI D+K WPNGLT+D +R+ W DA+ + I S YDG+ I+ E
Sbjct: 593 SGAGRKTIYK-DMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEY 651
Query: 641 LRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPD 700
L HPF+++ + VYWTDW + +ANK+ G++V I T P + +YHP RQP
Sbjct: 652 LSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSA--QPFDLQIYHPSRQPQ 709
Query: 701 GVNHCAAVNGH--CSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
N CAA +G CSH+CL ++ +CACP+ +KL D + C E K+
Sbjct: 710 APNPCAANDGKGPCSHMCLI-----NHNRSAACACPHLMKLSSDKKTCYEMKKF 758
Score = 205 bits (500), Expect = 5e-52
Identities = 132/396 (33%), Positives = 174/396 (43%), Gaps = 42/396 (10%)
Query: 19 ESRTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + C EF C C+ SW CD + DC D SDE T CQ +F C +G
Sbjct: 66 DQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDES----LDTSRTCQVDQFSC-GNG 120
Query: 78 LCIPRSWRCDATADCPDGSDE-HQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSD 135
CIPR+W CD DC D +DE CE C P +F C K G C+ W CD + DC D
Sbjct: 121 RCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVC--KSGRCISSKWHCDSDDDCGD 178
Query: 136 GSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQ 188
GSDE C +C ++F C +G+CI W E + C +P
Sbjct: 179 GSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNG 238
Query: 189 SHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
+ F C DG C+ W CDG+ DC DGSDE GC T +RS T+F C C+++A
Sbjct: 239 NEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGT--IRSCDHKTKFSCWSTGRCINKA 296
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDE- 304
WV E + C + C + C + + C+ CNG KDCPDGSDE
Sbjct: 297 WVCDGDIDCEDQSDE--DDC-DSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEG 353
Query: 305 Y---NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDR--CGENECEKN 359
Y C+ C G G+ VC CP +D C + N
Sbjct: 354 YLCDECSLNNGGCSNHCSVVPGRGI------VC----SCPEGLQLNKDNKTCEIVDYCSN 403
Query: 360 NGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ CSQ C C C +G+KL +D +C +D
Sbjct: 404 HLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVD 439
Score = 38.3 bits (85), Expect = 0.10
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 8/102 (7%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEM 458
G CS +C IN + C C + D+ C E LL+AR+ +IR + +D+
Sbjct: 721 GPCSHMCLINHNRSAACAC-PHLMKLSSDKKTCY--EMKKFLLYARRSEIRGVDIDNPYF 777
Query: 459 VAI----VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
I V D T +D+ ++W+D+ + I +A I+
Sbjct: 778 NFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFIN 819
>D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein.
Length = 793
Score = 452 bits (1115), Expect = e-126
Identities = 214/526 (40%), Positives = 309/526 (58%), Gaps = 17/526 (3%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C +F+C + C+ W E + C TC F C + CI
Sbjct: 47 CEKDQFQCRNE-RCIPSVWRCDEDDDCLDHSDE--DDCPKK-TCADSDFTCDNGHCIHER 102
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG--GGMCIPLSKVCDKHVDCPNFEDEP 347
C+G ++CPDGSDE T K +C + CG C+P S CD DC DE
Sbjct: 103 WKCDGEEECPDGSDESEATCTKQVCPAE-KLSCGPTSHKCVPASWRCDGEKDCEGGADEA 161
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICI 407
NEC NNGGCS C D IG+ C C G++L+D +TC DIDEC DP +CSQIC+
Sbjct: 162 GCATWLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICV 221
Query: 408 NEKGTFKCECHTGYARDPRDRTRCKATEGH-PSLLFARKHDIRKISLDHHEMVAIVNDTK 466
N KG FKCEC+ GY D + CKA G PSL+F ++++R+I L ++ K
Sbjct: 222 NYKGYFKCECYPGYEMDLLTKN-CKAAGGKSPSLIFTNRYEVRRIDLVKRNYSRLIPMLK 280
Query: 467 SATALDYVFRTGMIFWSDVNDEKIYKAPIDEGT---QRTVVIGEQLITSDGLAVDWVYNH 523
+ ALD T I+W D++ KIY A +D+ + ++ V+I EQL + +GLAVDWV+ H
Sbjct: 281 NVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKH 340
Query: 524 LYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGM 583
+YWTD+G+ I ++ + G R+ L L EPRAIA++PL G+M+W+DWG KIE++G+
Sbjct: 341 IYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGL 400
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRH 643
+G R T+VS +++WPNG+TLDL+ QR+YWVD+K++ +SS ++ G R+ ++ ST+ L H
Sbjct: 401 NGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSH 460
Query: 644 PFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVN 703
PF I FED V+WTD + A++ AN+ NG ++ + L NP I ++H +QP +
Sbjct: 461 PFGIAVFEDKVFWTDLENEAIFSANRLNGLEISIL--AENLNNPHDIVIFHELKQPRAPD 518
Query: 704 HC---AAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
C NG C +LCLPAP+ +SP+ +CACP+ + L PD + C
Sbjct: 519 ACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRC 564
Score = 120 bits (290), Expect = 1e-26
Identities = 50/125 (40%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
++ C +F+C+ RCIP W+CD + DC D SDED K C + F C +G C
Sbjct: 44 AKECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED----DCPKKTCADSDFTC-DNGHC 98
Query: 80 IPRSWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
I W+CD +CPDGSDE + C + C E+ +C +CVP +W CD DC G+
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGA 158
Query: 138 DEKAC 142
DE C
Sbjct: 159 DEAGC 163
Score = 102 bits (244), Expect = 5e-21
Identities = 48/128 (37%), Positives = 62/128 (48%), Gaps = 8/128 (6%)
Query: 100 QCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC-NETCRSDEFTCGNGKC 158
Q + C ++F CR + C+P W CD++ DC D SDE C +TC +FTC NG C
Sbjct: 41 QGPAKECEKDQFQCRNE--RCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHC 98
Query: 159 IQMRWVXXXXXX--XXXXXXEVKCPTPTCQPQSHFSC--TDGQCISAWWHCDGDVDCADG 214
I RW E C C P SC T +C+ A W CDG+ DC G
Sbjct: 99 IHERWKCDGEEECPDGSDESEATCTKQVC-PAEKLSCGPTSHKCVPASWRCDGEKDCEGG 157
Query: 215 SDEVGCVS 222
+DE GC +
Sbjct: 158 ADEAGCAT 165
Score = 89.4 bits (212), Expect = 4e-17
Identities = 52/139 (37%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFEC-LSDGLC 79
+TC S+F C G CI WKCD E++C D SDE C TK VC + C + C
Sbjct: 84 KTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATC--TKQVCPAEKLSCGPTSHKC 141
Query: 80 IPRSWRCDATADCPDGSDEHQCE--VEAC----GPEEFTCRG-KPG-ECV-PLTWMCDDN 130
+P SWRCD DC G+DE C + C G C K G EC P + D
Sbjct: 142 VPASWRCDGEKDCEGGADEAGCATWLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQ 201
Query: 131 PDCSD---GSDEKACNETC 146
C D D AC++ C
Sbjct: 202 KTCGDIDECKDPDACSQIC 220
Score = 71.3 bits (167), Expect = 1e-11
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 146 CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHC 205
C D+F C N +CI W E CP TC S F+C +G CI W C
Sbjct: 47 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCA-DSDFTCDNGHCIHERWKC 105
Query: 206 DGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI-TCVHRAW 248
DG+ +C DGSDE T +V C + + C CV +W
Sbjct: 106 DGEEECPDGSDESEATCTKQV---CPAEKLSCGPTSHKCVPASW 146
>AC008178-1|AAY24266.1| 773|Homo sapiens unknown protein.
Length = 773
Score = 433 bits (1066), Expect = e-120
Identities = 240/704 (34%), Positives = 341/704 (48%), Gaps = 38/704 (5%)
Query: 61 ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGEC 120
A+ C F C S G CIP WRCD T DC D +DE C V C F C+ + G+C
Sbjct: 23 ASGQECDSAHFRCGS-GHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSE-GQC 80
Query: 121 VPLTWMCDDNPDCSDGSDEKA-CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEV 178
+P +W+CD + DC DGSDE+ C++ TC S + TC NG+CI + E
Sbjct: 81 IPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADEN 140
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECN 238
C PTC+ +C +G C + CD VDC D SDE+ C C+ EF C
Sbjct: 141 DCQYPTCE---QLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEI------CLHNEFSCG 191
Query: 239 DRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ C+ RA+V E C TC QF C CI C+G DC
Sbjct: 192 NG-ECIPRAYVCDHDNDCQDGSDE--HACN-YPTCGGYQFTCPSGRCIYQNWVCDGEDDC 247
Query: 299 PDGSDEYNCT---RQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR---- 350
D DE C C R E+ C G CI + KVCD +DCP EDE
Sbjct: 248 KDNGDEDGCESGPHDVHKCSPR-EWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGSCSQICIN 408
C C N C +C +TP G C C GY + D+RTC + D+C G C Q C +
Sbjct: 307 CSMTLCSALN--CQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCES 364
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSA 468
G C C GY + + + G S++F+ D+ + +V
Sbjct: 365 RPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRG 424
Query: 469 TALDYVFRTGM--IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYW 526
A+ F + +FW+D K++ I+ G V+ + T + LAVDWV N +Y
Sbjct: 425 VAVGVAFHYHLQRVFWTDTVQNKVFSVDIN-GLNIQEVLNVSVETPENLAVDWVNNKIYL 483
Query: 527 TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV---PKIERAGM 583
+T N I++ +L G+ R LI + L PR IA++P G++F++DW + PK+ERA M
Sbjct: 484 VETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFM 543
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRH 643
DGS+R +V + WP G+TLD++ +RVYWVD++ + I + YDG R+ ++H ++ H
Sbjct: 544 DGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPH 603
Query: 644 PFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVN 703
PF ++ FE V++TDW K AV +ANKF + + P + VYH RQP N
Sbjct: 604 PFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASL--RPYGVTVYHSLRQPYATN 661
Query: 704 HCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
C NG C +C+ + R + C C G +L D++ C+
Sbjct: 662 PCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCI 705
Score = 237 bits (581), Expect = 8e-62
Identities = 192/666 (28%), Positives = 292/666 (43%), Gaps = 70/666 (10%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
+ + C S+ FRC +G CIP W+CD KDCSD +DE C + CQ+ F+C S+G
Sbjct: 23 ASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADE--IGCAV--VTCQQGYFKCQSEG 78
Query: 78 LCIPRSWRCDATADCPDGSDEHQ-CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP SW CD DC DGSDE Q C C + TC G+C+P + CD DC DG
Sbjct: 79 QCIPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSN--GQCIPSEYRCDHVRDCPDG 136
Query: 137 SDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
+DE C TC ++ TC NG C E+ C T C + FSC +
Sbjct: 137 ADENDCQYPTC--EQLTCDNGACYNTSQKCDWKVDCRDSSDEINC-TEICL-HNEFSCGN 192
Query: 196 GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXX 255
G+CI + CD D DC DGSDE C + P C +F C C+++ WV
Sbjct: 193 GECIPRAYVCDHDNDCQDGSDEHAC-NYP----TCGGYQFTCPSG-RCIYQNWVCDGEDD 246
Query: 256 XXXXXXE-ALELCRGNV-TCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK- 311
E E +V C ++ C + CI C+G+ DCP DE N + K
Sbjct: 247 CKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKY 306
Query: 312 ---TICDK-RTEFDCG----GGMCIPLSKVCDKHVD---CPNFEDEPRDRCGENECEKNN 360
T+C ++ C GG C H D C F+D C+
Sbjct: 307 CSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDD----------CQ-IW 355
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG 420
G C Q+C P + C CE+GY L + C+ D G S I N + + H
Sbjct: 356 GICDQKCESRPGRHLCHCEEGYILERGQYCKANDSF---GEASIIFSNGRDLLIGDIHGR 412
Query: 421 YAR---DPRDRTRCKATEGHPSL--LFARKHDIRKI------SLDHHEMVAIVNDTKSAT 469
R + ++R H L +F K+ L+ E++ + +T
Sbjct: 413 SFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENL 472
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTD- 528
A+D+V I+ + +I +D G+ R +I E L G+AVD +L+++D
Sbjct: 473 AVDWV--NNKIYLVETKVNRIDMVNLD-GSYRVTLITENLGHPRGIAVDPTVGYLFFSDW 529
Query: 529 ---TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDG 585
+G +E + + G+ RK L++ +L P + L+ + ++W D + IE DG
Sbjct: 530 ESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVD-SRFDYIETVTYDG 588
Query: 586 SHRSTIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHP 644
R T+V P+ + L +V++ D KM + + + + ++ ++ LR P
Sbjct: 589 IQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQAS--LR-P 645
Query: 645 FSITTF 650
+ +T +
Sbjct: 646 YGVTVY 651
Score = 41.9 bits (94), Expect = 0.008
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 14/112 (12%)
Query: 396 CADP-GSCSQICI------NEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI 448
C D G C Q+C+ N+ F+C+C G+ D +R C A + L+F+ + I
Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDER-HCIAVQNF--LIFSSQVAI 719
Query: 449 RKI----SLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
R I S MV + + +D+ + IF+SD++ I+K ID
Sbjct: 720 RGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKID 771
>AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density
lipoprotein receptor precursor variant protein.
Length = 555
Score = 430 bits (1060), Expect = e-120
Identities = 203/474 (42%), Positives = 261/474 (55%), Gaps = 17/474 (3%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 90 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 144
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC + C E +C +C+P++W CD DC G DE+
Sbjct: 145 RWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEE 204
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCI 199
C N TC DEFTC +G+CI +V E+ C PTC F C+ CI
Sbjct: 205 NCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHE-FQCSTSSCI 263
Query: 200 SAWWHCDGDVDCADGSDEV--GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
W CD D DC+D SDE C P + + C ++E +C C+H+ W
Sbjct: 264 PISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQCGSG-ECIHKKWRCDGDPDCK 322
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E C TCR DQF+C+D SCI G+ CNG++DC DGSDE NC + C
Sbjct: 323 DGSDEVN--CPSR-TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNC-KNVNQCLGP 378
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCD 377
+F C G CI +SKVC++ DC ++ DEP C NEC NNGGCS C D IGY CD
Sbjct: 379 GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECD 438
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C G++LID +TC DIDEC +PG CSQICIN KG +KCEC GY D CKA
Sbjct: 439 CAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGV-CKAVGKE 497
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIY 491
PSL+F + DIRKI L+ E + +V ++ ALD +FW+D++ + I+
Sbjct: 498 PSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIF 551
Score = 231 bits (566), Expect = 5e-60
Identities = 136/377 (36%), Positives = 175/377 (46%), Gaps = 32/377 (8%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-C 79
+TC S+F C G+C+P WKCD + DC D SDE P C C+ + C + C
Sbjct: 127 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--HMRTCRIHEISCGAHSTQC 184
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
IP SWRCD DC G DE C C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 185 IPVSWRCDGENDCDSGEDEENCGNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDE 242
Query: 140 KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKC---PT-PTCQPQSHFS 192
C TC + EF C CI + WV E +C P T P S
Sbjct: 243 LDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCPASEIQ 302
Query: 193 CTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
C G+CI W CDGD DC DGSDEV C S C +FEC D +C+H +
Sbjct: 303 CGSGECIHKKWRCDGDPDCKDGSDEVNCPS-----RTCRPDQFECEDG-SCIHGSRQCNG 356
Query: 253 XXXXXXXXXEALELCRG-NVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTR 309
E C+ N +F+C+ CI + CN +DC D SDE C
Sbjct: 357 IRDCVDGSDEV--NCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI 414
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRC 367
+ + + GG I V DC FE R CG+ +EC+ N G CSQ C
Sbjct: 415 NECLVNN------GGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQ-NPGICSQIC 467
Query: 368 VDTPIGYYCDCEKGYKL 384
++ GY C+C +GY++
Sbjct: 468 INLKGGYKCECSRGYQM 484
Score = 61.7 bits (143), Expect = 9e-09
Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
SRTC +F C+ G CI S +C+ +DC D SDE C +F+C S G C
Sbjct: 332 SRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE--VNCKNVNQCLGPGKFKCRS-GEC 388
Query: 80 IPRSWRCDATADCPDGSDE--HQCEVEAC 106
I S C+ DC D SDE +C + C
Sbjct: 389 IDISKVCNQEQDCRDWSDEPLKECHINEC 417
>AC010740-1|AAY14689.1| 862|Homo sapiens unknown protein.
Length = 862
Score = 427 bits (1052), Expect = e-119
Identities = 241/671 (35%), Positives = 350/671 (52%), Gaps = 46/671 (6%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNE--TCRS-DEFTCGNGKCIQMR 162
C ++F+C G C+P W+CD DC D +DE A E TC +F C +G+CI +
Sbjct: 3 CQVDQFSCGN--GRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSK 60
Query: 163 WVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGC 220
W EV C +C + F C+ G+CI W CDGD DC D SDE + C
Sbjct: 61 WHCDSDDDCGDGSDEVGC-VHSCF-DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINC 118
Query: 221 VSTPKVRSP--CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT-C-RLD 276
++ SP C EF+C+ CV W E + C G + C
Sbjct: 119 TKE-EIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDE--KGCNGTIRLCDHKT 175
Query: 277 QFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGG--GMCIPLSKV 333
+F C CI A C+G DC D SDE +C +C + C +C+ K+
Sbjct: 176 KFSCWSTGRCINKAWVCDGDIDCEDQSDEDDC--DSFLCGP-PKHPCANDTSVCLQPEKL 232
Query: 334 CDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTP-IGYYCDCEKGYKLI-DNRTCE 391
C+ DCP+ DE C +EC NNGGCS C P G C C +G +L DN+TCE
Sbjct: 233 CNGKKDCPDGSDEGY-LC--DECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCE 289
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS-LLFARKHDIRK 450
+D C++ CSQ+C K T KC C+ G+ D D C + + + ++F+ +H+IR+
Sbjct: 290 IVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDV-DGESCTSVDPFEAFIIFSIRHEIRR 348
Query: 451 ISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGE 507
I L + +V ++ ALD+ F +++W+DV +++IY+ + E + VV+
Sbjct: 349 IDLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEH 408
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
L T +GL VDW+ ++YW D+ + IE++ L G++R LI +E PRAIAL+P G +
Sbjct: 409 GLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGIL 468
Query: 568 FWTDW-GQVPKIERAGMDGSHRSTIVSYDVK---WPNGLTLDLVRQRVYWVDAKMNTISS 623
FWTDW P+IE A M G+ R TI D+K WPNGLT+D +R+ W DA+ + I S
Sbjct: 469 FWTDWDANFPRIESASMSGAGRKTIYK-DMKTGAWPNGLTVDHFEKRIVWTDARSDAIYS 527
Query: 624 CNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHT 683
YDG+ I+ E L HPF+++ + VYWTDW + +ANK+ G++V I T
Sbjct: 528 ALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSA 587
Query: 684 LQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLCLPAPRFGPNSPRVSCACPNGLKLLP 741
P + +YHP RQP N CAA +G CSH+CL ++ +CACP+ +KL
Sbjct: 588 --QPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLI-----NHNRSAACACPHLMKLSS 640
Query: 742 DDQMCVEDSKY 752
D + C E K+
Sbjct: 641 DKKTCYEMKKF 651
Score = 155 bits (377), Expect = 4e-37
Identities = 116/355 (32%), Positives = 153/355 (43%), Gaps = 49/355 (13%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGLC 79
RTC +F C GRCIP +W CD E DC D +DE + + C+ +F C S G C
Sbjct: 1 RTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE---MASCEFPTCEPLTQFVCKS-GRC 56
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
I W CD+ DC DGSDE C V +C +F C G C+P W CD + DC D SDE
Sbjct: 57 ISSKWHCDSDDDCGDGSDEVGC-VHSCFDNQFRC--SSGRCIPGHWACDGDNDCGDFSDE 113
Query: 140 KACNET---------CRSDEFTC-GNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQP 187
N T C +EF C +G C+ W E C C
Sbjct: 114 AQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDH 173
Query: 188 QSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVS--TPKVRSPCISTEFECNDRITCV 244
++ FSC + G+CI+ W CDGD+DC D SDE C S + PC ND C+
Sbjct: 174 KTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPC------ANDTSVCL 227
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDH-SCIPG-ALYCNGVKDCPDGS 302
+ E LC C L+ C +H S +PG + C+ CP+G
Sbjct: 228 QPEKLCNGKKDCPDGSDEGY-LCD---ECSLNNGGCSNHCSVVPGRGIVCS----CPEGL 279
Query: 303 DEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKH---VDCPNFEDEPRDRCGEN 354
+ I D C + S+VC++H V C +E D GE+
Sbjct: 280 QLNKDNKTCEIVDY-----CSNH--LKCSQVCEQHKHTVKCSCYEGWKLDVDGES 327
Score = 122 bits (293), Expect = 6e-27
Identities = 79/256 (30%), Positives = 131/256 (51%), Gaps = 16/256 (6%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEM 458
G CS +C IN + C C + D+ C E LL+AR+ +IR + +D+
Sbjct: 614 GPCSHMCLINHNRSAACAC-PHLMKLSSDKKTCY--EMKKFLLYARRSEIRGVDIDNPYF 670
Query: 459 VAI----VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
I V D T +D+ ++W+D+ + I +A I+ GT VI + + G
Sbjct: 671 NFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFIN-GTGLETVISRDIQSIRG 729
Query: 515 LAVDWVYNHLYW--TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +LYW ++ I ++ L G+++ +I +++P+ +A +P+ G ++WTD
Sbjct: 730 LAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHG-IDKPQCLAAHPVRGKLYWTDG 788
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+ S I+ + K P GL++D V ++YW+ + TI+ CN DG
Sbjct: 789 NT---INMANMDGSN-SKILFQNQKEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLE 844
Query: 633 LILHSTEVLRHPFSIT 648
+I E L ++T
Sbjct: 845 VIESMKEELTKATALT 860
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/107 (37%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Query: 272 TCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
TC++DQF C + CIP A C+ DC D +DE T C+ T+F C G CI
Sbjct: 2 TCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPT-CEPLTQFVCKSGRCISSK 60
Query: 332 KVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCD 377
CD DC + DE C + C N CS RC+ P + CD
Sbjct: 61 WHCDSDDDCGDGSDEV--GC-VHSCFDNQFRCSSGRCI--PGHWACD 102
>AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1731
Score = 425 bits (1047), Expect = e-118
Identities = 240/671 (35%), Positives = 349/671 (52%), Gaps = 46/671 (6%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNE--TCRS-DEFTCGNGKCIQMR 162
C ++F+C G C+P W+CD DC D +DE A E TC +F C +G+CI +
Sbjct: 3 CQVDQFSCGN--GRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSK 60
Query: 163 WVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE--VGC 220
W EV C +C + F C+ G+CI W CDGD DC D SDE + C
Sbjct: 61 WHCDSDDDCGDGSDEVGC-VHSCF-DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINC 118
Query: 221 VSTPKVRSP--CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT-C-RLD 276
++ SP C EF+C+ CV W E + C G + C
Sbjct: 119 TKE-EIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDE--KGCNGTIRLCDHKT 175
Query: 277 QFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGG--GMCIPLSKV 333
+F C CI A C+G DC D SDE +C +C + C +C+ K+
Sbjct: 176 KFSCWSTGRCINKAWVCDGDIDCEDQSDEDDC--DSFLCGP-PKHPCANDTSVCLQPEKL 232
Query: 334 CDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTP-IGYYCDCEKGYKLI-DNRTCE 391
C+ DCP+ DE C +EC NNGGCS C P G C C +G +L DN+TCE
Sbjct: 233 CNGKKDCPDGSDEGY-LC--DECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCE 289
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS-LLFARKHDIRK 450
+D C++ CSQ+C K T KC C+ G+ D D C + + + ++F+ +H+IR+
Sbjct: 290 IVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDV-DGESCTSVDSFEAFIIFSIRHEIRR 348
Query: 451 ISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEG---TQRTVVIGE 507
I L + +V ++ ALD+ F +++W+DV +++IY+ + E + VV+
Sbjct: 349 IDLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEH 408
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
L T +GL VDW+ ++YW D+ + IE++ L G++R LI +E PRAIAL+P G +
Sbjct: 409 GLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGIL 468
Query: 568 FWTDW-GQVPKIERAGMDGSHRSTIVSYDVK---WPNGLTLDLVRQRVYWVDAKMNTISS 623
FWTDW P+IE A M G+ R TI D+K WPNGLT+D +R+ W DA+ + I S
Sbjct: 469 FWTDWDANFPRIESASMSGAGRKTIYK-DMKTGAWPNGLTVDHFEKRIVWTDARSDAIYS 527
Query: 624 CNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHT 683
YDG+ I+ E L HPF+++ + VYWTDW + +ANK+ G++V I T
Sbjct: 528 ALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSA 587
Query: 684 LQNPMVIHVYHPYRQPDGVNHCAAVNGH--CSHLCLPAPRFGPNSPRVSCACPNGLKLLP 741
P + +YHP RQP N CAA +G CSH+CL ++ +CACP+ +KL
Sbjct: 588 --QPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLI-----NHNRSAACACPHLMKLSS 640
Query: 742 DDQMCVEDSKY 752
D + C K+
Sbjct: 641 DKKTCYGMKKF 651
Score = 203 bits (495), Expect = 2e-51
Identities = 123/379 (32%), Positives = 201/379 (53%), Gaps = 24/379 (6%)
Query: 383 KLIDNRTCEDIDECA-DPGSCSQICINEKGTFK-CECHTGYARDPRDRTRCKATEGHPSL 440
K+ D + + C + G CSQ+C+ T + C C GY ++R C+ E L
Sbjct: 901 KVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQ-KNRMSCQGIESF--L 957
Query: 441 LFARKHDIRKISL---DHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
+++ IR I L D + + ++ T A +D+ I+W+D+ KI +A D+
Sbjct: 958 MYSVHEGIRGIPLEPSDKMDALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQ 1017
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
T + +I L +G+AVDW+ ++YWTD G N IE++ L G+ R ++I L++PR+
Sbjct: 1018 -TWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQPRS 1076
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
IA++P +G +FWT+WGQ+P I +A +DGS + +VS + WPNG+++D ++YW DA+
Sbjct: 1077 IAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDAR 1136
Query: 618 MNTISSCNYD-GSGRRLILHSTEVLRHPFSITTFEDWVYWTD--WDKTAVYRANKFNGKD 674
+ I + + G R ++L + V FS+ F ++YW+D +V R +K +
Sbjct: 1137 TDKIERIDLETGGNREMVLSGSNV--DMFSVAXFGAYIYWSDRAHANGSVRRGHKNDA-- 1192
Query: 675 VEAITSTHTL-QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCAC 733
E IT L N + +++ R+ G N CA NG C LCL + NS R +CAC
Sbjct: 1193 TETITMRTGLGVNLKEVKIFNRVRE-KGTNVCARDNGGCKQLCL----YRGNSRR-TCAC 1246
Query: 734 PNGLKLLPDDQMCVEDSKY 752
+G L D C+ Y
Sbjct: 1247 AHGY-LAEDGVTCLRHEGY 1264
Score = 153 bits (372), Expect = 2e-36
Identities = 115/354 (32%), Positives = 152/354 (42%), Gaps = 49/354 (13%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGLCI 80
TC +F C GRCIP +W CD E DC D +DE + + C+ +F C S G CI
Sbjct: 2 TCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE---MASCEFPTCEPLTQFVCKS-GRCI 57
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD+ DC DGSDE C V +C +F C G C+P W CD + DC D SDE
Sbjct: 58 SSKWHCDSDDDCGDGSDEVGC-VHSCFDNQFRC--SSGRCIPGHWACDGDNDCGDFSDEA 114
Query: 141 ACNET---------CRSDEFTC-GNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQPQ 188
N T C +EF C +G C+ W E C C +
Sbjct: 115 QINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHK 174
Query: 189 SHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVS--TPKVRSPCISTEFECNDRITCVH 245
+ FSC + G+CI+ W CDGD+DC D SDE C S + PC ND C+
Sbjct: 175 TKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPC------ANDTSVCLQ 228
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDH-SCIPG-ALYCNGVKDCPDGSD 303
+ E LC C L+ C +H S +PG + C+ CP+G
Sbjct: 229 PEKLCNGKKDCPDGSDEGY-LCD---ECSLNNGGCSNHCSVVPGRGIVCS----CPEGLQ 280
Query: 304 EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKH---VDCPNFEDEPRDRCGEN 354
+ I D C + S+VC++H V C +E D GE+
Sbjct: 281 LNKDNKTCEIVDY-----CSNH--LKCSQVCEQHKHTVKCSCYEGWKLDVDGES 327
Score = 151 bits (366), Expect = 9e-36
Identities = 109/373 (29%), Positives = 182/373 (48%), Gaps = 36/373 (9%)
Query: 396 CA-DPGSCSQICINEKGTFK-CECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISL 453
CA D G C Q+C+ + + C C GY + D C EG+ LL++ + ++ I L
Sbjct: 1223 CARDNGGCKQLCLYRGNSRRTCACAHGYLAE--DGVTCLRHEGY--LLYSGRTILKSIHL 1278
Query: 454 -DHHEMVAIVNDTKS--------ATALDYVFR---TGMIFWSDVNDEKIYKAPIDEGTQR 501
D + + + ++ A A DY R T IF+SD + I D R
Sbjct: 1279 SDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIK-DNWEDR 1337
Query: 502 TVVIGEQLITSDGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEP 555
V++ E + + +GLA ++ LYWT T H + + ++ + P
Sbjct: 1338 QVIV-ENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHP 1396
Query: 556 RAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV 614
+AL+ + MFWT+W Q P I R+ + G + +VS D+ PNGLT+D +++Y+
Sbjct: 1397 HVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFS 1456
Query: 615 DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKD 674
D + I C YDGS R +I+ S S+ ++++++W+DW + A+ R+NK+ G D
Sbjct: 1457 DGSLGKIERCEYDGSQRHVIVKSGPGTF--LSLAVYDNYIFWSDWGRRAILRSNKYTGGD 1514
Query: 675 VEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACP 734
+ + S Q +I V + + ++ CA +NG C LCL P + RV+C+C
Sbjct: 1515 TKILRSDIPHQPMGIIAVANDTNSCE-LSPCALLNGGCHDLCLLTP-----NGRVNCSC- 1567
Query: 735 NGLKLLPDDQMCV 747
G ++L +D CV
Sbjct: 1568 RGDRILLEDNRCV 1580
Score = 148 bits (358), Expect = 8e-35
Identities = 105/374 (28%), Positives = 176/374 (47%), Gaps = 28/374 (7%)
Query: 400 GSCSQIC-INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEM 458
G CS +C IN + C C + D+ C + LL+AR+ +IR + +D+
Sbjct: 614 GPCSHMCLINHNRSAACAC-PHLMKLSSDKKTCYGMKKF--LLYARRSEIRGVDIDNPYF 670
Query: 459 VAI----VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG 514
I V D T +D+ ++W+D+ + I +A I+ GT VI + + G
Sbjct: 671 NFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFIN-GTGLETVISRDIQSIRG 729
Query: 515 LAVDWVYNHLYW--TDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LAVDWV +LYW ++ I ++ L G+++ +I +++P+ +A +P+ G ++WTD
Sbjct: 730 LAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHG-IDKPQCLAAHPVRGKLYWTDG 788
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
I A MDGS+ S I+ + K P GL++D V ++YW+ + TI+ CN DG
Sbjct: 789 NT---INMANMDGSN-SKILFQNQKEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLE 844
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH- 691
+I E L ++T + ++W D + + +K +G++ + + + V+H
Sbjct: 845 VIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRN----KTSGVVHM 900
Query: 692 -VYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
VY Q G N C NG CS LCLP + +C C G L + C
Sbjct: 901 KVYDKEAQ-QGSNSCQLNNGGCSQLCLPT-----SETTRTCMCTVGYYLQKNRMSCQGIE 954
Query: 751 KYHFLPFYNNFRSI 764
+ + R I
Sbjct: 955 SFLMYSVHEGIRGI 968
Score = 97.9 bits (233), Expect = 1e-19
Identities = 50/129 (38%), Positives = 63/129 (48%), Gaps = 6/129 (4%)
Query: 18 SESRTCTS-SEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+++ +C + SEF C G CI CD C D SDE C C+ F+ +
Sbjct: 1581 TKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRS--CRR-GFKPCYN 1637
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP CD DC D SDE C+V C EF C G C+P + C+ N DC+D
Sbjct: 1638 RRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRC--ADGTCIPRSARCNQNIDCADA 1695
Query: 137 SDEKACNET 145
SDEK CN T
Sbjct: 1696 SDEKNCNNT 1704
Score = 77.8 bits (183), Expect = 1e-13
Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 7/92 (7%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE-DPTVCTATKMVCQEYRFECL 74
L+ E+R+C C RCIP CD E DC D+SDE D V T C F C
Sbjct: 1621 LYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST-----CATVEFRC- 1674
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEAC 106
+DG CIPRS RC+ DC D SDE C C
Sbjct: 1675 ADGTCIPRSARCNQNIDCADASDEKNCNNTDC 1706
Score = 74.5 bits (175), Expect = 1e-12
Identities = 43/117 (36%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 110 EFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA--C-NETCRSDEFTCGNGKCIQMRWVXX 166
EF C GEC+ CD P C D SDEK C N +CR C N +CI +
Sbjct: 1591 EFECGN--GECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCD 1648
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVST 223
E+ C TC F C DG CI C+ ++DCAD SDE C +T
Sbjct: 1649 GENDCGDNSDELDCKVSTCATVE-FRCADGTCIPRSARCNQNIDCADASDEKNCNNT 1704
Score = 72.1 bits (169), Expect = 7e-12
Identities = 48/150 (32%), Positives = 62/150 (41%), Gaps = 11/150 (7%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEK-DCSDSSDE---DPTVCTATKMVCQEY-RFE 72
+++ +C S G C L N + +CS D + C C Y FE
Sbjct: 1534 NDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFE 1593
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDEH--QCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C +G CI CD C D SDE CE +C C + C+P +CD
Sbjct: 1594 C-GNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNR--RCIPHGKLCDGE 1650
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCI 159
DC D SDE C TC + EF C +G CI
Sbjct: 1651 NDCGDNSDELDCKVSTCATVEFRCADGTCI 1680
Score = 69.7 bits (163), Expect = 4e-11
Identities = 47/154 (30%), Positives = 65/154 (42%), Gaps = 10/154 (6%)
Query: 206 DGDVDCADGSDEVGCVSTPKV--RSPCIS-TEFECNDRITCVHRAWVXXXXXXXXXXXXE 262
+G V+C+ D + V S C + +EFEC + C+ E
Sbjct: 1560 NGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNG-ECIDYQLTCDGIPHCKDKSDE 1618
Query: 263 ALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC 322
L C N +CR C + CIP C+G DC D SDE +C K EF C
Sbjct: 1619 KLLYCE-NRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC---KVSTCATVEFRC 1674
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC 356
G CIP S C++++DC + DE C +C
Sbjct: 1675 ADGTCIPRSARCNQNIDCADASDE--KNCNNTDC 1706
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/107 (37%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Query: 272 TCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
TC++DQF C + CIP A C+ DC D +DE T C+ T+F C G CI
Sbjct: 2 TCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPT-CEPLTQFVCKSGRCISSK 60
Query: 332 KVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCD 377
CD DC + DE C + C N CS RC+ P + CD
Sbjct: 61 WHCDSDDDCGDGSDEV--GC-VHSCFDNQFRCSSGRCI--PGHWACD 102
Score = 59.3 bits (137), Expect = 5e-08
Identities = 42/124 (33%), Positives = 57/124 (45%), Gaps = 7/124 (5%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C S F C +G+CI CDG C D SDE + + RS C C +R C
Sbjct: 1585 SCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEK--LLYCENRS-CRRGFKPCYNR-RC 1640
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ + E L+ C+ + TC +F+C D +CIP + CN DC D SD
Sbjct: 1641 IPHGKLCDGENDCGDNSDE-LD-CKVS-TCATVEFRCADGTCIPRSARCNQNIDCADASD 1697
Query: 304 EYNC 307
E NC
Sbjct: 1698 EKNC 1701
Score = 53.6 bits (123), Expect = 3e-06
Identities = 73/316 (23%), Positives = 118/316 (37%), Gaps = 25/316 (7%)
Query: 352 GENECEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNRTC-EDIDECADPGSCSQICINE 409
G N C ++NGGC Q C+ C C GY D TC G I+
Sbjct: 1219 GTNVCARDNGGCKQLCLYRGNSRRTCACAHGYLAEDGVTCLRHEGYLLYSGRTILKSIHL 1278
Query: 410 KGTFKCECHTGYARDPRDRTRCKA--------TEGHPSLLFARKH--DIRKISLDHHEMV 459
+PR A +G + ++ H +I+ I + +
Sbjct: 1279 SDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQ 1338
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDG----- 514
IV + S L Y ++W+ I + +D+ T+ E +IT
Sbjct: 1339 VIVENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQ-TRPGAFDREAVITMSEDDHPH 1397
Query: 515 -LAVDWVYNHLYWTDTGHNH--IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
LA+D N ++WT+ H I S L G ++++ + P + ++ ++++D
Sbjct: 1398 VLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSD 1457
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
G + KIER DGS R IV L+L + ++W D I N G
Sbjct: 1458 -GSLGKIERCEYDGSQRHVIVKSGP--GTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGD 1514
Query: 632 RLILHSTEVLRHPFSI 647
IL S ++ P I
Sbjct: 1515 TKILRS-DIPHQPMGI 1529
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 303 DEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGG 362
++ C + + C+ +EF+CG G CI CD C + DE C C +
Sbjct: 1575 EDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKP 1634
Query: 363 C-SQRCVDTPIGYYC----DCEKGYKLIDNR--TCEDID-ECADPGSC 402
C ++RC+ P G C DC +D + TC ++ CAD G+C
Sbjct: 1635 CYNRRCI--PHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD-GTC 1679
Score = 48.8 bits (111), Expect = 7e-05
Identities = 27/64 (42%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE---DPTVCT-ATKMVCQEYRF-ECLSD 76
TC + EFRC G CIP S +C+ DC+D+SDE + T CT K+ + F C S
Sbjct: 1666 TCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNST 1725
Query: 77 GLCI 80
LC+
Sbjct: 1726 SLCV 1729
Score = 42.7 bits (96), Expect = 0.005
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 352 GENECEKNNGGCSQRCVDT-PIGYYCDCEKGYKLIDNR-TCEDID 394
G N C+ NNGGCSQ C+ T C C GY L NR +C+ I+
Sbjct: 910 GSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGIE 954
>AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1537
Score = 403 bits (993), Expect = e-111
Identities = 234/660 (35%), Positives = 331/660 (50%), Gaps = 41/660 (6%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVX 165
C F+C G C+ TW+CD DC DG DE C+ +C ++F C KCI W+
Sbjct: 6 CEENYFSCPS--GRCILNTWICDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWIC 63
Query: 166 XXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQ-CISAWWHCDGDVDCADGSDEVGCVS 222
E C TC FSC + C+ W CDG+ DC DGSDE+
Sbjct: 64 DGEDDCGDGLDESDSICGAITCAADM-FSCQGSRACVPRHWLCDGERDCPDGSDELSTAG 122
Query: 223 TPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD 282
+ C F C++++ C+ + +V E+ + C G C ++F C D
Sbjct: 123 CAP-NNTCDENAFMCHNKV-CIPKQFVCDHDDDCGDGSDESPQ-C-GYRQCGTEEFSCAD 178
Query: 283 HSCIPGALY-CNGVKDCPDGSDEY----NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKH 337
C+ + C+G DCPD SDE C C+ + F C G CIP +CD
Sbjct: 179 GRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAXQSCNS-SFFMCKNGRCIPSGGLCDNK 237
Query: 338 VDCPNFEDEPRDRCGENEC-EKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
DC + DE C NEC K GCSQ C D P+ Y C C G++L D+ +TC DIDE
Sbjct: 238 DDCGDGSDERN--CHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDE 295
Query: 396 CADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA-TEGHPSLLFARKHDIRKISLD 454
C+ CSQ CIN GT+KC C GY P + CK+ ++ P L+ A H+IRKIS D
Sbjct: 296 CSSGFPCSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKISTD 355
Query: 455 HHEMVAIVNDTKSATALDYVFRTGMIFWSDV---NDEKIYKAPIDEGTQRTVVIGEQLIT 511
+ + A+D+ +R I+W D N +I + ++ G+ VV
Sbjct: 356 GSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLN-GSDIKVV--HNTAV 412
Query: 512 SDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTD 571
+ LAVDW+ +LYW+DT IE+S L G IL+ RL+ PR ++L+P G+++W D
Sbjct: 413 PNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWID 472
Query: 572 WGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGR 631
+ P I R GMDG+++S ++ + P LT+D V +R+YW D N I N DGS R
Sbjct: 473 CCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADE--NHIEFSNMDGSHR 530
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKD-VEAITSTHTLQNPMVI 690
+ + + ++T FED++YWTD ++ RA+K +G D + I S H + + I
Sbjct: 531 HKV--PNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHAITD---I 585
Query: 691 HVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
VYH YRQPD H C NG CSHLCL AP +CACP L D++ C+ +
Sbjct: 586 QVYHSYRQPDVSKHLCMINNGGCSHLCLLAP-----GKTHTCACPTNFYLAADNRTCLSN 640
Score = 380 bits (936), Expect = e-105
Identities = 249/775 (32%), Positives = 361/775 (46%), Gaps = 78/775 (10%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED---PTVCTATKMVCQEYRFECLS 75
+ +TC EF+CK CIP W+CD++ DCSD+SDE+ P CT +C +
Sbjct: 796 DKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC--------A 847
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+G C+ + CD DC DGSDE CE +C ++F C G+C+P W CD + DC
Sbjct: 848 NGDCVSSRFWCDGDFDCADGSDERNCET-SCSKDQFRCSN--GQCIPAKWKCDGHEDCKY 904
Query: 136 GSDEKAC---NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFS 192
G DEK+C + TC S E+ C + CI E+ C T C+ + F
Sbjct: 905 GEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTE-CK-EDQFR 962
Query: 193 CTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C + CI W CDG DC DGSDE C + C + EF CN+ + +H WV
Sbjct: 963 CKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNI---CRADEFLCNNSLCKLH-FWVCD 1018
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
EA ++C + +C+++ C+ CNG+ +C D SDE +C +
Sbjct: 1019 GEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGK 1078
Query: 311 KTI----CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGCS 364
T C K+ EF C CIP+ CD+ DC + DE R E CE N C
Sbjct: 1079 LTYKARPC-KKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCG 1137
Query: 365 QR--CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C +C C+ G++ + NR CED++EC G+CS CIN +G++KC C +
Sbjct: 1138 DDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNF 1197
Query: 422 ARDPRDRTRCKATEGHPSLLF-ARKHDIR------KISLDHHEMVAIVNDTKSATALDYV 474
R+ T C A +L+ A DI S DH ++ I ++++ T +D
Sbjct: 1198 --QERNNT-CIAEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSR-ITGMDVY 1253
Query: 475 FRTGMIFWS-DVNDEKIYKAPIDEGTQRTV---VIGEQLITSDGLAVDWVYNHLYWTDTG 530
++ MI WS N I+ I +R +I + +AVDWV ++YWTD
Sbjct: 1254 YQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHS 1313
Query: 531 HNH---------------IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV 575
H I + L G L+ + EP AIA+NP G M+WT G
Sbjct: 1314 RMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDH 1373
Query: 576 PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A MDG+ R +V +++ P GL +D +R+YW D +++ I S YDGS + +
Sbjct: 1374 SHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSV 1433
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
S + L HP I FED++Y K V+R KF VE + + + + H
Sbjct: 1434 SSKQGLLHPHRIDIFEDYIYGAG-PKNGVFRVQKFGHGSVEYLAL--NIDKTKGVLISHR 1490
Query: 696 YRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
Y+Q D N C ++ C LCL N +C CP G L+ + C +DS
Sbjct: 1491 YKQLDLPNPC--LDLACEFLCL------LNPSGATCVCPEGKYLI--NGTCNDDS 1535
Score = 260 bits (636), Expect = 2e-68
Identities = 193/721 (26%), Positives = 323/721 (44%), Gaps = 74/721 (10%)
Query: 22 TCTSSEFRCKTGR-CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+C+ F+CKT + CI W CD + DC+D+SDE K C + F+C ++ CI
Sbjct: 759 SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE----ANCDKKTCGPHEFQCKNNN-CI 813
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
P WRCD+ DC D SDE C+ + C ++F C G+CV + CD + DC+DGSDE+
Sbjct: 814 PDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCAN--GDCVSSRFWCDGDFDCADGSDER 871
Query: 141 ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQPQSHFSCTDGQC 198
C +C D+F C NG+CI +W E C +PTC + + +DG C
Sbjct: 872 NCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG-C 930
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
ISA C+G+ DCADGSDE+ CV + C +F C ++ C+ W+
Sbjct: 931 ISASLKCNGEYDCADGSDEMDCV------TECKEDQFRCKNKAHCIPIRWLCDGIHDCVD 984
Query: 259 XXXEALELC-RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E E C RG CR D+F C + C C+G DC D SDE K +C
Sbjct: 985 GSDE--ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPST 1042
Query: 318 TEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCG------ENECEKNNGGCS-QRCVD 369
C +C+ ++C+ +C + DE D CG C+K+ CS ++C+
Sbjct: 1043 RPHRCRNNRICLQSEQMCNGIDECGDNSDE--DHCGGKLTYKARPCKKDEFACSNKKCI- 1099
Query: 370 TPIGYYC----DC-----EKGYKLIDNR-TCED-IDECADPGSCSQICINEKGTFKCECH 418
P+ C DC E+G ++ TCED ++ C D C+QI K + C C
Sbjct: 1100 -PMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQI----KTSVFCRCK 1154
Query: 419 TGYARDPRDRTRCKATEGHPSLLFAR-KHDIRKISLDHHEMVAIVN-DTKSATALDYVFR 476
G+ R+ ++R +C+ + + L+F H + ++ V N ++ T +
Sbjct: 1155 PGFQRNMKNR-QCE--DLNECLVFGTCSHQCINVE-GSYKCVCDQNFQERNNTCIAEGSE 1210
Query: 477 TGMIFWSDVNDEKIYKAPID-EGTQRTVVIGEQLITSDGLAVDWVYNHLYW-TDTGHNHI 534
+++ ++ D + P + G + + E G+ V + + + W T I
Sbjct: 1211 DQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGI 1270
Query: 535 ELSDLQGNMRKI----LIRDRLEEPRAIALNPLEGWMFWTD-------------WGQVP- 576
+ G ++ LI + PR IA++ + G ++WTD W +
Sbjct: 1271 FYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRY 1330
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW-VDAKMNTISSCNYDGSGRRLIL 635
I ++G + + +++ P + ++ R +YW V + I DG+ RR+++
Sbjct: 1331 SINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILV 1390
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
++ F + +YW D++ + + V +++S L +P I ++
Sbjct: 1391 QKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFED 1450
Query: 696 Y 696
Y
Sbjct: 1451 Y 1451
Score = 226 bits (553), Expect = 2e-58
Identities = 129/370 (34%), Positives = 167/370 (45%), Gaps = 26/370 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L +++RTC T+S+FRCKT +CIP WKCD DC D SDE P C + CQ
Sbjct: 628 FYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDCPEFR--CQPG 684
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
RF+C GLC ++ CD DC D SDE C+ C +F C K +C+P+ C+
Sbjct: 685 RFQC-GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCT-KNQKCIPVNLRCNG 742
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXEVKCPTPTCQP 187
DC D DE+ C E +C D F C K CI WV E C TC P
Sbjct: 743 QDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGP 802
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
F C + CI W CD DC+D SDE C P+ C +F C + R
Sbjct: 803 H-EFQCKNNNCIPDHWRCDSQNDCSDNSDEENC--KPQT---CTLKDFLCANGDCVSSRF 856
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W E +C DQF+C + CIP C+G +DC G DE +C
Sbjct: 857 WCDGDFDCADGSDERNCE-----TSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSC 911
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
C R E+ C CI S C+ DC + DE C EC+++ C +
Sbjct: 912 EPASPTCSSR-EYICASDGCISASLKCNGEYDCADGSDEM--DC-VTECKEDQFRCKNKA 967
Query: 368 VDTPIGYYCD 377
PI + CD
Sbjct: 968 HCIPIRWLCD 977
Score = 147 bits (357), Expect = 1e-34
Identities = 87/229 (37%), Positives = 110/229 (48%), Gaps = 22/229 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C + F C +GRCI +W CD +KDC D DE C ++ C +F C S CI +
Sbjct: 6 CEENYFSCPSGRCILNTWICDGQKDCEDGRDE--FHCDSS---CSWNQFAC-SAQKCISK 59
Query: 83 SWRCDATADCPDGSDEHQ--CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W CD DC DG DE C C + F+C+G CVP W+CD DC DGSDE
Sbjct: 60 HWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRA-CVPRHWLCDGERDCPDGSDEL 118
Query: 141 -----ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQPQSHFSCT 194
A N TC + F C N CI ++V E +C C + FSC
Sbjct: 119 STAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTE-EFSCA 177
Query: 195 DGQC-ISAWWHCDGDVDCADGSDEVGCVSTPKVRS---PCISTEFECND 239
DG+C ++ W CDGD DC D SDE PK +S C S+ F C +
Sbjct: 178 DGRCLLNTQWQCDGDFDCPDHSDEAPL--NPKCKSAXQSCNSSFFMCKN 224
Score = 147 bits (357), Expect = 1e-34
Identities = 77/212 (36%), Positives = 102/212 (48%), Gaps = 18/212 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
+C+ ++F C +CI W CD E DC D DE ++C A + C F C C+P
Sbjct: 43 SCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGA--ITCAADMFSCQGSRACVP 100
Query: 82 RSWRCDATADCPDGSDEHQ---CEV-EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
R W CD DCPDGSDE C C F C K C+P ++CD + DC DGS
Sbjct: 101 RHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNK--VCIPKQFVCDHDDDCGDGS 158
Query: 138 DEK-ACN-ETCRSDEFTCGNGKC-IQMRWVXXXXXXXXXXXXEV----KCPT--PTCQPQ 188
DE C C ++EF+C +G+C + +W E KC + +C
Sbjct: 159 DESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAXQSCN-S 217
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C +G+CI + CD DC DGSDE C
Sbjct: 218 SFFMCKNGRCIPSGGLCDNKDDCGDGSDERNC 249
Score = 100 bits (239), Expect = 2e-20
Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 13/131 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+ TC + F C CIP + CD++ DC D SDE P C + C F C +DG C
Sbjct: 126 NNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQ-CGYRQ--CGTEEFSC-ADGRC 181
Query: 80 IPRS-WRCDATADCPDGSDE----HQCE--VEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
+ + W+CD DCPD SDE +C+ ++C F C K G C+P +CD+ D
Sbjct: 182 LLNTQWQCDGDFDCPDHSDEAPLNPKCKSAXQSCNSSFFMC--KNGRCIPSGGLCDNKDD 239
Query: 133 CSDGSDEKACN 143
C DGSDE+ C+
Sbjct: 240 CGDGSDERNCH 250
Score = 87.0 bits (206), Expect = 2e-16
Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 21 RTCTSSEFRCKTGRCI-PLSWKCDNEKDCSDSSDEDPT--VCTATKMVCQEYRFECLSDG 77
R C + EF C GRC+ W+CD + DC D SDE P C + C F C +G
Sbjct: 167 RQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAXQSCNSSFFMC-KNG 225
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP CD DC DGSDE C + C ++ + + + +P+++ C P
Sbjct: 226 RCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKD 285
Query: 138 DEKACNETCR-SDEFTCGNGKCI 159
D K C + S F C +CI
Sbjct: 286 DGKTCVDIDECSSGFPCSQ-QCI 307
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S ++C SS F CK GRCIP CDN+ DC D SDE C + + ++ C D
Sbjct: 210 SAXQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE--RNCHINECLSKKVS-GCSQDC 266
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTC 113
+P S++C D C +++ C F C
Sbjct: 267 QDLPVSYKCKCWPGFQLKDDGKTCVDIDECS-SGFPC 302
>AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein.
Length = 1576
Score = 385 bits (947), Expect = e-106
Identities = 188/412 (45%), Positives = 256/412 (62%), Gaps = 18/412 (4%)
Query: 333 VCDKHVDCPNFEDE-PRDRC----GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-D 386
+C+ DC + DE P+ C GE C NNGGC+Q+C C C GY+L D
Sbjct: 1 LCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTED 60
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKH 446
TC+D++ECA+ G CSQ C N +G F+C C TGY P DR CKA P LLFA +
Sbjct: 61 GHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRP-DRRSCKALGPEPVLLFANRI 119
Query: 447 DIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG 506
DIR++ E ++N+ ++A ALD+ R ++FWSDV ++I +A ++ G+ V+
Sbjct: 120 DIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLN-GSNVEEVVS 178
Query: 507 EQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGW 566
L + GLAVDWV++ LYWTD+G + IE+++L G RK+L+ LE+PRAIAL+P+EG
Sbjct: 179 TGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGT 238
Query: 567 MFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNY 626
++WTDWG P+IE + MDGS R I + WPNGLT+D +R+YWVDAK + I N
Sbjct: 239 IYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANL 298
Query: 627 DGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQN 686
DGS R+ ++ ++ L HPF+IT FED +YWTDW ++ ANKF GK+ E I + L
Sbjct: 299 DGSHRKAVI--SQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEII--RNKLHF 354
Query: 687 PMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLK 738
PM IH HP RQP G N C NG C+HLCLP+ G N +CACP G +
Sbjct: 355 PMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPS---GQN---YTCACPTGFR 400
Score = 293 bits (720), Expect = 1e-78
Identities = 150/357 (42%), Positives = 210/357 (58%), Gaps = 17/357 (4%)
Query: 394 DECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
+ C D G C+ +C+ + C C TG+ + + A LLFAR+ DIR+IS
Sbjct: 371 NRCGDNNGGCTHLCLPSGQNYTCACPTGFRKIS---SHACAQSLDKFLLFARRMDIRRIS 427
Query: 453 LDHHEM---VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQL 509
D ++ V + D +SA ALD+ R ++W+DV+ + I +A D GT + VV+ L
Sbjct: 428 FDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWD-GTGQEVVVDTSL 486
Query: 510 ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFW 569
+ GLA+DWV N LYWTD G + IE+++ G+MR +LI + L+ PR I + P+ G+M+W
Sbjct: 487 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 546
Query: 570 TDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGS 629
TDWG PKIERAGMD S R I+S ++ WPNGL +D QR+YW DA M TI DGS
Sbjct: 547 TDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGS 606
Query: 630 GRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMV 689
R++++ S L HPF +T + + +YWTDW ++ A++ G D E T L+N M
Sbjct: 607 KRKVLIGSQ--LPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRE--TLQENLENLMD 662
Query: 690 IHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
IHV+H R+P CA NG CSHLCL + PN SC CP G+ LL D + C
Sbjct: 663 IHVFH-RRRPPVSTPCAMENGGCSHLCLRS----PNPSGFSCTCPTGINLLSDGKTC 714
Score = 274 bits (672), Expect = 8e-73
Identities = 144/350 (41%), Positives = 210/350 (60%), Gaps = 22/350 (6%)
Query: 400 GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD---HH 456
G CS +C+ F C C TG +T + E + LLF+ + IR+ISLD H
Sbjct: 989 GGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETY--LLFSSRGSIRRISLDTSDHT 1046
Query: 457 EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLA 516
++ V + + +LDY G ++++DV + I +A ++ G+ VIG L T+DGLA
Sbjct: 1047 DVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLN-GSNMETVIGRGLKTTDGLA 1105
Query: 517 VDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVP 576
VDWV +LYWTDTG N IE S L G+ RK+LI + L+EPRAIA+ P +G++FWTDWG +
Sbjct: 1106 VDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIA 1165
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILH 636
KIERA +DGS R +++ D+ WPNGLTLD +R+YWVDA ++ I S + +G R++++
Sbjct: 1166 KIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVG 1225
Query: 637 STEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ HPF++T + W+YWTDW ++ R +K++G++ E + + ++ M I V P
Sbjct: 1226 H---VSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLA--NVEGLMDIIVVSPQ 1280
Query: 697 RQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
RQ G N C NG C+HLC F S V CACP+ PD Q C
Sbjct: 1281 RQ-TGTNACGVNNGGCTHLC-----FARASDFV-CACPDE----PDSQPC 1319
Score = 250 bits (611), Expect = 2e-65
Identities = 135/358 (37%), Positives = 202/358 (56%), Gaps = 22/358 (6%)
Query: 396 CA-DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKIS 452
CA + G CS +C+ F C C TG +T L+FAR+ DIR +S
Sbjct: 677 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSF--LIFARRIDIRMVS 734
Query: 453 LD---HHEMVAIVNDT-KSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQ 508
LD ++V +N T K+ A+ + G ++WSD +I +A +D G+Q +I
Sbjct: 735 LDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLD-GSQHEDIITTG 793
Query: 509 LITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMF 568
L T+DGLAVD + +YWTDTG N IE+ +L G+MRK+L+ L+ PRAI L G+M+
Sbjct: 794 LQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMY 853
Query: 569 WTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
WTDWG+ K+ER+GMDGS R+ +++ ++ WPNGLT+D ++ W DA I + + +G
Sbjct: 854 WTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNG 913
Query: 629 SGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPM 688
+ R ++ ++HP+ +T + ++YWTDW +++RA+K G +V + S L M
Sbjct: 914 ANRHTLV---SPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRS--NLPGLM 968
Query: 689 VIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ QP G N C + NG CSHLCLP P SCACP G++L D + C
Sbjct: 969 DMQAV-DRAQPLGFNKCGSRNGGCSHLCLPRP------SGFSCACPTGIQLKGDGKTC 1019
Score = 105 bits (252), Expect = 6e-22
Identities = 76/285 (26%), Positives = 130/285 (45%), Gaps = 13/285 (4%)
Query: 348 RDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDECADPGSCSQIC 406
R G+N C NNGGC+ C+ + Y C C G++ I + C + +D+ I
Sbjct: 365 RQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIR 424
Query: 407 INEKGTFKCECHTGYARDPRDRTRC--KATEGHPSLLFARKHDIRKISLDHHEMVAIVN- 463
T D R + + H I + D +V+
Sbjct: 425 RISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT 484
Query: 464 --DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVY 521
++ + A+D+V T ++W+D ++I A D G+ RTV+I E L + V+ +
Sbjct: 485 SLESPAGLAIDWV--TNKLYWTDAGTDRIEVANTD-GSMRTVLIWENLDRPRDIVVEPMG 541
Query: 522 NHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIER 580
++YWTD G + IE + + + R+++I L P +A++ ++W D G + IE
Sbjct: 542 GYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAG-MKTIEF 600
Query: 581 AGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
AG+DGS R ++ + P GLT L +R+YW D + +I S +
Sbjct: 601 AGLDGSKRKVLIGSQLPHPFGLT--LYGERIYWTDWQTKSIQSAD 643
Score = 102 bits (245), Expect = 4e-21
Identities = 100/376 (26%), Positives = 166/376 (44%), Gaps = 35/376 (9%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDC--GGGMCIPLSKVCDKHVDCPNFE----D 345
CNGV DC D SDE + Q+ + E +C G C ++ V C
Sbjct: 2 CNGVNDCGDNSDE---SPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLT 58
Query: 346 EPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCS 403
E C + NEC + G CSQ C ++ + C CE GY+L D R+C+ + +
Sbjct: 59 EDGHTCQDVNECAE-EGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFAN 117
Query: 404 QICINEKGTFKCECHTGYARDPRDRTRCKATEGH--PSLLFARKHDIRKI------SLDH 455
+I I + + E Y + A + H L+F + +I +
Sbjct: 118 RIDIRQVLPHRSE----YTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNV 173
Query: 456 HEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGL 515
E+V+ ++ A+D+V ++W+D +I A +D G R V++ + L +
Sbjct: 174 EEVVSTGLESPGGLAVDWVH--DKLYWTDSGTSRIEVANLD-GAHRKVLLWQNLEKPRAI 230
Query: 516 AVDWVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ 574
A+ + +YWTD G+ IE S + G+ R+I+ L P + ++ M+W D +
Sbjct: 231 ALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVD-AK 289
Query: 575 VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRL 633
IERA +DGSHR ++S + P +T + +YW D +I+S N + G + +
Sbjct: 290 HHVIERANLDGSHRKAVISQGLPHPFAIT--VFEDSLYWTDWHTKSINSANKFTGKNQEI 347
Query: 634 ILHSTEVLRHPFSITT 649
I + L P I T
Sbjct: 348 IRNK---LHFPMDIHT 360
Score = 95.9 bits (228), Expect = 5e-19
Identities = 82/301 (27%), Positives = 134/301 (44%), Gaps = 20/301 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC----ADPGSCSQIC 406
G N+C NGGCS C+ P G+ C C G +L D +TC+ E + GS +I
Sbjct: 980 GFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRIS 1039
Query: 407 INEKGTFKCECHTGYAR-DPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN-- 463
++ + H + + +G IR+ L+ M ++
Sbjct: 1040 LDTSD--HTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRG 1097
Query: 464 -DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYN 522
T A+D+V R ++W+D I + +D G+ R V+I L +AV
Sbjct: 1098 LKTTDGLAVDWVARN--LYWTDTGRNTIEASRLD-GSCRKVLINNSLDEPRAIAVFPRKG 1154
Query: 523 HLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERA 581
+L+WTD GH IE ++L G+ RK+LI L P + L+ ++W D + +IE A
Sbjct: 1155 YLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVD-AHLDRIESA 1213
Query: 582 GMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLILHSTEV 640
++G R +V + V P LT + +YW D + +I + Y G + +L + E
Sbjct: 1214 DLNGKLRQVLVGH-VSHPFALTQQ--DRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEG 1270
Query: 641 L 641
L
Sbjct: 1271 L 1271
Score = 92.3 bits (219), Expect = 6e-18
Identities = 80/298 (26%), Positives = 132/298 (44%), Gaps = 33/298 (11%)
Query: 356 CEKNNGGCSQRCV--DTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
C NGGCS C+ P G+ C C G L+ D +TC PG S + +
Sbjct: 677 CAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTC-------SPGMNSFLIFARRID 729
Query: 413 FK-CECHTGYARD---PRDRTR-------CKATEGHPSLLFARKHDIRKISLD---HHEM 458
+ Y D P + T EG + H I + +LD H ++
Sbjct: 730 IRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDI 789
Query: 459 VAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVD 518
+ T A+D + R ++W+D +I +D G+ R V++ + L + + +
Sbjct: 790 ITTGLQTTDGLAVDAIGR--KVYWTDTGTNRIEVGNLD-GSMRKVLVWQNLDSPRAIVLY 846
Query: 519 WVYNHLYWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
+YWTD G N +E S + G+ R +LI + L P + ++ + W D +
Sbjct: 847 HEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWAD-AHTER 905
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A ++G++R T+VS V+ P GLT L+ +YW D + +I + G+G +IL
Sbjct: 906 IEAADLNGANRHTLVS-PVQHPYGLT--LLDSYIYWTDWQTRSIHRAD-KGTGSNVIL 959
Score = 33.1 bits (72), Expect = 3.8
Identities = 12/32 (37%), Positives = 16/32 (50%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDC 378
P+ + G N C NNGGC+ C + C C
Sbjct: 1279 PQRQTGTNACGVNNGGCTHLCFARASDFVCAC 1310
>AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.
Length = 1126
Score = 380 bits (936), Expect = e-105
Identities = 249/775 (32%), Positives = 361/775 (46%), Gaps = 78/775 (10%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED---PTVCTATKMVCQEYRFECLS 75
+ +TC EF+CK CIP W+CD++ DCSD+SDE+ P CT +C +
Sbjct: 330 DKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC--------A 381
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+G C+ + CD DC DGSDE CE +C ++F C G+C+P W CD + DC
Sbjct: 382 NGDCVSSRFWCDGDFDCADGSDERNCET-SCSKDQFRCSN--GQCIPAKWKCDGHEDCKY 438
Query: 136 GSDEKAC---NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFS 192
G DEK+C + TC S E+ C + CI E+ C T C+ + F
Sbjct: 439 GEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTE-CK-EDQFR 496
Query: 193 CTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C + CI W CDG DC DGSDE C + C + EF CN+ + +H WV
Sbjct: 497 CKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNI---CRADEFLCNNSLCKLH-FWVCD 552
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
EA ++C + +C+++ C+ CNG+ +C D SDE +C +
Sbjct: 553 GEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGK 612
Query: 311 KTI----CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGCS 364
T C K+ EF C CIP+ CD+ DC + DE R E CE N C
Sbjct: 613 LTYKARPC-KKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCG 671
Query: 365 QR--CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C +C C+ G++ + NR CED++EC G+CS CIN +G++KC C +
Sbjct: 672 DDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNF 731
Query: 422 ARDPRDRTRCKATEGHPSLLF-ARKHDIR------KISLDHHEMVAIVNDTKSATALDYV 474
R+ T C A +L+ A DI S DH ++ I ++++ T +D
Sbjct: 732 --QERNNT-CIAEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSR-ITGMDVY 787
Query: 475 FRTGMIFWS-DVNDEKIYKAPIDEGTQRTV---VIGEQLITSDGLAVDWVYNHLYWTDTG 530
++ MI WS N I+ I +R +I + +AVDWV ++YWTD
Sbjct: 788 YQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHS 847
Query: 531 HNH---------------IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV 575
H I + L G L+ + EP AIA+NP G M+WT G
Sbjct: 848 RMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDH 907
Query: 576 PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A MDG+ R +V +++ P GL +D +R+YW D +++ I S YDGS + +
Sbjct: 908 SHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSV 967
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
S + L HP I FED++Y K V+R KF VE + + + + H
Sbjct: 968 SSKQGLLHPHRIDIFEDYIYGAG-PKNGVFRVQKFGHGSVEYLAL--NIDKTKGVLISHR 1024
Query: 696 YRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
Y+Q D N C ++ C LCL N +C CP G L+ + C +DS
Sbjct: 1025 YKQLDLPNPC--LDLACEFLCL------LNPSGATCVCPEGKYLI--NGTCNDDS 1069
Score = 260 bits (636), Expect = 2e-68
Identities = 193/721 (26%), Positives = 323/721 (44%), Gaps = 74/721 (10%)
Query: 22 TCTSSEFRCKTGR-CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+C+ F+CKT + CI W CD + DC+D+SDE K C + F+C ++ CI
Sbjct: 293 SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE----ANCDKKTCGPHEFQCKNNN-CI 347
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
P WRCD+ DC D SDE C+ + C ++F C G+CV + CD + DC+DGSDE+
Sbjct: 348 PDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCAN--GDCVSSRFWCDGDFDCADGSDER 405
Query: 141 ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQPQSHFSCTDGQC 198
C +C D+F C NG+CI +W E C +PTC + + +DG C
Sbjct: 406 NCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG-C 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
ISA C+G+ DCADGSDE+ CV + C +F C ++ C+ W+
Sbjct: 465 ISASLKCNGEYDCADGSDEMDCV------TECKEDQFRCKNKAHCIPIRWLCDGIHDCVD 518
Query: 259 XXXEALELC-RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E E C RG CR D+F C + C C+G DC D SDE K +C
Sbjct: 519 GSDE--ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPST 576
Query: 318 TEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCG------ENECEKNNGGCS-QRCVD 369
C +C+ ++C+ +C + DE D CG C+K+ CS ++C+
Sbjct: 577 RPHRCRNNRICLQSEQMCNGIDECGDNSDE--DHCGGKLTYKARPCKKDEFACSNKKCI- 633
Query: 370 TPIGYYC----DC-----EKGYKLIDNR-TCED-IDECADPGSCSQICINEKGTFKCECH 418
P+ C DC E+G ++ TCED ++ C D C+QI K + C C
Sbjct: 634 -PMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQI----KTSVFCRCK 688
Query: 419 TGYARDPRDRTRCKATEGHPSLLFAR-KHDIRKISLDHHEMVAIVN-DTKSATALDYVFR 476
G+ R+ ++R +C+ + + L+F H + ++ V N ++ T +
Sbjct: 689 PGFQRNMKNR-QCE--DLNECLVFGTCSHQCINVE-GSYKCVCDQNFQERNNTCIAEGSE 744
Query: 477 TGMIFWSDVNDEKIYKAPID-EGTQRTVVIGEQLITSDGLAVDWVYNHLYW-TDTGHNHI 534
+++ ++ D + P + G + + E G+ V + + + W T I
Sbjct: 745 DQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGI 804
Query: 535 ELSDLQGNMRKI----LIRDRLEEPRAIALNPLEGWMFWTD-------------WGQVP- 576
+ G ++ LI + PR IA++ + G ++WTD W +
Sbjct: 805 FYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRY 864
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW-VDAKMNTISSCNYDGSGRRLIL 635
I ++G + + +++ P + ++ R +YW V + I DG+ RR+++
Sbjct: 865 SINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILV 924
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
++ F + +YW D++ + + V +++S L +P I ++
Sbjct: 925 QKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFED 984
Query: 696 Y 696
Y
Sbjct: 985 Y 985
Score = 226 bits (553), Expect = 2e-58
Identities = 129/370 (34%), Positives = 167/370 (45%), Gaps = 26/370 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L +++RTC T+S+FRCKT +CIP WKCD DC D SDE P C + CQ
Sbjct: 162 FYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDCPEFR--CQPG 218
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
RF+C GLC ++ CD DC D SDE C+ C +F C K +C+P+ C+
Sbjct: 219 RFQC-GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCT-KNQKCIPVNLRCNG 276
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXEVKCPTPTCQP 187
DC D DE+ C E +C D F C K CI WV E C TC P
Sbjct: 277 QDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGP 336
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
F C + CI W CD DC+D SDE C P+ C +F C + R
Sbjct: 337 H-EFQCKNNNCIPDHWRCDSQNDCSDNSDEENC--KPQT---CTLKDFLCANGDCVSSRF 390
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W E +C DQF+C + CIP C+G +DC G DE +C
Sbjct: 391 WCDGDFDCADGSDERNCE-----TSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSC 445
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
C R E+ C CI S C+ DC + DE C EC+++ C +
Sbjct: 446 EPASPTCSSR-EYICASDGCISASLKCNGEYDCADGSDEM--DC-VTECKEDQFRCKNKA 501
Query: 368 VDTPIGYYCD 377
PI + CD
Sbjct: 502 HCIPIRWLCD 511
Score = 129 bits (312), Expect = 3e-29
Identities = 70/186 (37%), Positives = 102/186 (54%), Gaps = 14/186 (7%)
Query: 566 WMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
+++W D + P I R GMDG+++S ++ + P LT+D V +R+YW D N I N
Sbjct: 1 YLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADE--NHIEFSN 58
Query: 626 YDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKD-VEAITSTHTL 684
DGS R + + + ++T FED++YWTD ++ RA+K +G D + I S H +
Sbjct: 59 MDGSHRHKV--PNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHAI 116
Query: 685 QNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDD 743
+ I VYH YRQPD H C NG CSHLCL AP +CACP L D+
Sbjct: 117 TD---IQVYHSYRQPDVSKHLCMINNGGCSHLCLLAP-----GKTHTCACPTNFYLAADN 168
Query: 744 QMCVED 749
+ C+ +
Sbjct: 169 RTCLSN 174
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 6/97 (6%)
Query: 497 EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPR 556
+GT ++VVI ++ L +D+V LYW D NHIE S++ G+ R + + P
Sbjct: 19 DGTNQSVVIETKISRPMALTIDYVNRRLYWAD--ENHIEFSNMDGSHRHKVPNQDI--PG 74
Query: 557 AIALNPLEGWMFWTDWGQVPKIERA-GMDGSHRSTIV 592
IAL E +++WTD G+ + RA G+ R +++
Sbjct: 75 VIALTLFEDYIYWTD-GKTKSLSRAHKTSGADRLSLI 110
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC-------INEKGTFKC 415
C C+ P G C C +G LI N TC D D D SC C +NEKG +C
Sbjct: 1039 CEFLCLLNPSGATCVCPEGKYLI-NGTCND-DSLLDD-SCKLTCENGGRCILNEKGDLRC 1095
Query: 416 ECHTGYARDPRDRTRC 431
C Y+ + + C
Sbjct: 1096 HCWPSYSGERCEVNHC 1111
Score = 33.9 bits (74), Expect = 2.2
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 356 CEKNNGGCSQRCVDTP-IGYYCDCEKGYKL-IDNRTC 390
C NNGGCS C+ P + C C + L DNRTC
Sbjct: 135 CMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRTC 171
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 380 bits (936), Expect = e-105
Identities = 249/775 (32%), Positives = 361/775 (46%), Gaps = 78/775 (10%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED---PTVCTATKMVCQEYRFECLS 75
+ +TC EF+CK CIP W+CD++ DCSD+SDE+ P CT +C +
Sbjct: 593 DKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLC--------A 644
Query: 76 DGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
+G C+ + CD DC DGSDE CE +C ++F C G+C+P W CD + DC
Sbjct: 645 NGDCVSSRFWCDGDFDCADGSDERNCET-SCSKDQFRCSN--GQCIPAKWKCDGHEDCKY 701
Query: 136 GSDEKAC---NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFS 192
G DEK+C + TC S E+ C + CI E+ C T C+ + F
Sbjct: 702 GEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTE-CK-EDQFR 759
Query: 193 CTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C + CI W CDG DC DGSDE C + C + EF CN+ + +H WV
Sbjct: 760 CKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNI---CRADEFLCNNSLCKLH-FWVCD 815
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQ 310
EA ++C + +C+++ C+ CNG+ +C D SDE +C +
Sbjct: 816 GEDDCGDNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGK 875
Query: 311 KTI----CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE--CEKNNGGCS 364
T C K+ EF C CIP+ CD+ DC + DE R E CE N C
Sbjct: 876 LTYKARPC-KKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCG 934
Query: 365 QR--CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C +C C+ G++ + NR CED++EC G+CS CIN +G++KC C +
Sbjct: 935 DDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNF 994
Query: 422 ARDPRDRTRCKATEGHPSLLF-ARKHDIR------KISLDHHEMVAIVNDTKSATALDYV 474
R+ T C A +L+ A DI S DH ++ I ++++ T +D
Sbjct: 995 --QERNNT-CIAEGSEDQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSR-ITGMDVY 1050
Query: 475 FRTGMIFWS-DVNDEKIYKAPIDEGTQRTV---VIGEQLITSDGLAVDWVYNHLYWTDTG 530
++ MI WS N I+ I +R +I + +AVDWV ++YWTD
Sbjct: 1051 YQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHS 1110
Query: 531 HNH---------------IELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV 575
H I + L G L+ + EP AIA+NP G M+WT G
Sbjct: 1111 RMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDH 1170
Query: 576 PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
IE A MDG+ R +V +++ P GL +D +R+YW D +++ I S YDGS + +
Sbjct: 1171 SHIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSV 1230
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
S + L HP I FED++Y K V+R KF VE + + + + H
Sbjct: 1231 SSKQGLLHPHRIDIFEDYIYGAG-PKNGVFRVQKFGHGSVEYLAL--NIDKTKGVLISHR 1287
Query: 696 YRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDS 750
Y+Q D N C ++ C LCL N +C CP G L+ + C +DS
Sbjct: 1288 YKQLDLPNPC--LDLACEFLCL------LNPSGATCVCPEGKYLI--NGTCNDDS 1332
Score = 302 bits (741), Expect = 3e-81
Identities = 170/451 (37%), Positives = 241/451 (53%), Gaps = 26/451 (5%)
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGCSQ 365
C + C+ + F C G CIP +CD DC + DE C NEC K GCSQ
Sbjct: 5 CKSAEQSCNS-SFFMCKNGRCIPSGGLCDNKDDCGDGSDERN--CHINECLSKKVSGCSQ 61
Query: 366 RCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYARD 424
C D P+ Y C C G++L D+ +TC DIDEC+ CSQ CIN GT+KC C GY
Sbjct: 62 DCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQ 121
Query: 425 PRDRTRCKA-TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWS 483
P + CK+ ++ P L+ A H+IRKIS D + + A+D+ +R I+W
Sbjct: 122 PDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWI 181
Query: 484 DV---NDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQ 540
D N +I + ++ G+ VV + LAVDW+ +LYW+DT IE+S L
Sbjct: 182 DSSRPNGSRINRMCLN-GSDIKVV--HNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLN 238
Query: 541 GNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPN 600
G IL+ RL+ PR ++L+P G+++W D + P I R GMDG+++S ++ + P
Sbjct: 239 GLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPM 298
Query: 601 GLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWD 660
LT+D V +R+YW D N I N DGS R + + + ++T FED++YWTD
Sbjct: 299 ALTIDYVNRRLYWADE--NHIEFSNMDGSHRHKV--PNQDIPGVIALTLFEDYIYWTDGK 354
Query: 661 KTAVYRANKFNGKD-VEAITSTHTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLP 718
++ RA+K +G D + I S H + + I VYH YRQPD H C NG CSHLCL
Sbjct: 355 TKSLSRAHKTSGADRLSLIYSWHAITD---IQVYHSYRQPDVSKHLCMINNGGCSHLCLL 411
Query: 719 APRFGPNSPRVSCACPNGLKLLPDDQMCVED 749
AP +CACP L D++ C+ +
Sbjct: 412 AP-----GKTHTCACPTNFYLAADNRTCLSN 437
Score = 260 bits (636), Expect = 2e-68
Identities = 193/721 (26%), Positives = 323/721 (44%), Gaps = 74/721 (10%)
Query: 22 TCTSSEFRCKTGR-CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+C+ F+CKT + CI W CD + DC+D+SDE K C + F+C ++ CI
Sbjct: 556 SCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE----ANCDKKTCGPHEFQCKNNN-CI 610
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
P WRCD+ DC D SDE C+ + C ++F C G+CV + CD + DC+DGSDE+
Sbjct: 611 PDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCAN--GDCVSSRFWCDGDFDCADGSDER 668
Query: 141 ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC--PTPTCQPQSHFSCTDGQC 198
C +C D+F C NG+CI +W E C +PTC + + +DG C
Sbjct: 669 NCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDG-C 727
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
ISA C+G+ DCADGSDE+ CV + C +F C ++ C+ W+
Sbjct: 728 ISASLKCNGEYDCADGSDEMDCV------TECKEDQFRCKNKAHCIPIRWLCDGIHDCVD 781
Query: 259 XXXEALELC-RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR 317
E E C RG CR D+F C + C C+G DC D SDE K +C
Sbjct: 782 GSDE--ENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPST 839
Query: 318 TEFDC-GGGMCIPLSKVCDKHVDCPNFEDEPRDRCG------ENECEKNNGGCS-QRCVD 369
C +C+ ++C+ +C + DE D CG C+K+ CS ++C+
Sbjct: 840 RPHRCRNNRICLQSEQMCNGIDECGDNSDE--DHCGGKLTYKARPCKKDEFACSNKKCI- 896
Query: 370 TPIGYYC----DC-----EKGYKLIDNR-TCED-IDECADPGSCSQICINEKGTFKCECH 418
P+ C DC E+G ++ TCED ++ C D C+QI K + C C
Sbjct: 897 -PMDLQCDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQI----KTSVFCRCK 951
Query: 419 TGYARDPRDRTRCKATEGHPSLLFAR-KHDIRKISLDHHEMVAIVN-DTKSATALDYVFR 476
G+ R+ ++R +C+ + + L+F H + ++ V N ++ T +
Sbjct: 952 PGFQRNMKNR-QCE--DLNECLVFGTCSHQCINVE-GSYKCVCDQNFQERNNTCIAEGSE 1007
Query: 477 TGMIFWSDVNDEKIYKAPID-EGTQRTVVIGEQLITSDGLAVDWVYNHLYW-TDTGHNHI 534
+++ ++ D + P + G + + E G+ V + + + W T I
Sbjct: 1008 DQVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGI 1067
Query: 535 ELSDLQGNMRKI----LIRDRLEEPRAIALNPLEGWMFWTD-------------WGQVP- 576
+ G ++ LI + PR IA++ + G ++WTD W +
Sbjct: 1068 FYKRIHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRY 1127
Query: 577 KIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW-VDAKMNTISSCNYDGSGRRLIL 635
I ++G + + +++ P + ++ R +YW V + I DG+ RR+++
Sbjct: 1128 SINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILV 1187
Query: 636 HSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHP 695
++ F + +YW D++ + + V +++S L +P I ++
Sbjct: 1188 QKNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFED 1247
Query: 696 Y 696
Y
Sbjct: 1248 Y 1248
Score = 226 bits (553), Expect = 2e-58
Identities = 129/370 (34%), Positives = 167/370 (45%), Gaps = 26/370 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L +++RTC T+S+FRCKT +CIP WKCD DC D SDE P C + CQ
Sbjct: 425 FYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDCPEFR--CQPG 481
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
RF+C GLC ++ CD DC D SDE C+ C +F C K +C+P+ C+
Sbjct: 482 RFQC-GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCT-KNQKCIPVNLRCNG 539
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCGNGK-CIQMRWVXXXXXXXXXXXXEVKCPTPTCQP 187
DC D DE+ C E +C D F C K CI WV E C TC P
Sbjct: 540 QDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGP 599
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
F C + CI W CD DC+D SDE C P+ C +F C + R
Sbjct: 600 H-EFQCKNNNCIPDHWRCDSQNDCSDNSDEENC--KPQT---CTLKDFLCANGDCVSSRF 653
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
W E +C DQF+C + CIP C+G +DC G DE +C
Sbjct: 654 WCDGDFDCADGSDERNCE-----TSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSC 708
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
C R E+ C CI S C+ DC + DE C EC+++ C +
Sbjct: 709 EPASPTCSSR-EYICASDGCISASLKCNGEYDCADGSDEM--DC-VTECKEDQFRCKNKA 764
Query: 368 VDTPIGYYCD 377
PI + CD
Sbjct: 765 HCIPIRWLCD 774
Score = 59.7 bits (138), Expect = 4e-08
Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 13/118 (11%)
Query: 272 TCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRT--EFDCGGGMCIP 329
+C F CK+ CIP C+ DC DGSDE NC + + K + DC +P
Sbjct: 11 SCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDC---QDLP 67
Query: 330 LSKVCDKHVDC-PNFE--DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
+S C C P F+ D+ + +EC + CSQ+C++T Y C C GY++
Sbjct: 68 VSYKC----KCWPGFQLKDDGKTCVDIDEC-SSGFPCSQQCINTYGTYKCLCTDGYEI 120
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S ++C SS F CK GRCIP CDN+ DC D SDE C + + ++ C D
Sbjct: 7 SAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE--RNCHINECLSKKVS-GCSQDC 63
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTC 113
+P S++C D C +++ C F C
Sbjct: 64 QDLPVSYKCKCWPGFQLKDDGKTCVDIDECS-SGFPC 99
Score = 53.2 bits (122), Expect = 3e-06
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Query: 59 CTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPG 118
C + + C F C +G CIP CD DC DGSDE C + C ++ + +
Sbjct: 5 CKSAEQSCNSSFFMC-KNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDC 63
Query: 119 ECVPLTWMCDDNPDCSDGSDEKACNETCR-SDEFTCGNGKCI 159
+ +P+++ C P D K C + S F C +CI
Sbjct: 64 QDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQ-QCI 104
Score = 39.9 bits (89), Expect = 0.033
Identities = 16/32 (50%), Positives = 19/32 (59%)
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C +G+CI + CD DC DGSDE C
Sbjct: 15 SFFMCKNGRCIPSGGLCDNKDDCGDGSDERNC 46
Score = 39.9 bits (89), Expect = 0.033
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC-------INEKGTFKC 415
C C+ P G C C +G LI N TC D D D SC C +NEKG +C
Sbjct: 1302 CEFLCLLNPSGATCVCPEGKYLI-NGTCND-DSLLDD-SCKLTCENGGRCILNEKGDLRC 1358
Query: 416 ECHTGYARDPRDRTRC 431
C Y+ + + C
Sbjct: 1359 HCWPSYSGERCEVNHC 1374
>BC126405-1|AAI26406.1| 1613|Homo sapiens low density lipoprotein
receptor-related protein 6 protein.
Length = 1613
Score = 299 bits (735), Expect = 2e-80
Identities = 143/320 (44%), Positives = 201/320 (62%), Gaps = 14/320 (4%)
Query: 431 CKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRTGMIFWSDVNDE 488
C P LL+A + D+R + + + A +V + A A+D+VF G+I+WSDV++E
Sbjct: 14 CVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEE 73
Query: 489 KIYKAPID--EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKI 546
I + + E Q VV G L++ DGLA DW+ LYWTD+ N IE+S+L G++RK+
Sbjct: 74 AIKRTEFNKTESVQNVVVSG--LLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKV 131
Query: 547 LIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDL 606
L L++PRAIAL+P G+M+WTDWG+VPKIERAGMDGS R I++ ++ WPNGLTLD
Sbjct: 132 LFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDY 191
Query: 607 VRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYR 666
Q++YW DAK+N I N DG+ R+ ++ + L HPF++T FED +YWTDW ++
Sbjct: 192 EEQKLYWADAKLNFIHKSNLDGTNRQAVVKGS--LPHPFALTLFEDILYWTDWSTHSILA 249
Query: 667 ANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNS 726
NK+ G+ + I S + +PM IH + RQP+ N C NG CSHLCL P
Sbjct: 250 CNKYTGEGLREIHS--DIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCL----MSPVK 303
Query: 727 PRVSCACPNGLKLLPDDQMC 746
P CACP G+KLL + + C
Sbjct: 304 PFYQCACPTGVKLLENGKTC 323
Score = 272 bits (667), Expect = 3e-72
Identities = 149/357 (41%), Positives = 207/357 (57%), Gaps = 24/357 (6%)
Query: 398 DPGSCSQICINE--KGTFKCECHTGYARDPRDRTRCK--ATEGHPSLLFARKHDIRKISL 453
D G CS +C+ K ++C C TG +T CK ATE LL AR+ D+R+ISL
Sbjct: 289 DNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKT-CKDGATE---LLLLARRTDLRRISL 344
Query: 454 DHHEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLI 510
D + IV D + A A+DY G I+W+D I ++ ID G+ V+ Q+
Sbjct: 345 DTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFID-GSGSQFVVTAQIA 403
Query: 511 TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
DG+AVDWV +LYWTDTG + IE++ L G MRKILI + LEEPRAI L+P+ G+M+WT
Sbjct: 404 HPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWT 463
Query: 571 DWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSG 630
DWG++PKIERA +DGS R +V+ + WPNGL LD ++YW DAK + I N DG+G
Sbjct: 464 DWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTG 523
Query: 631 RRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVI 690
RR+++ + + H F T D+VYWTDW + ++ R +K + + I L
Sbjct: 524 RRVLVE--DKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKAT 581
Query: 691 HVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+V+ G N CA NG CSHLCL P+ + CACP G +L+ D + C+
Sbjct: 582 NVHRVI----GSNPCAEENGGCSHLCLYRPQ------GLRCACPIGFELISDMKTCI 628
Score = 264 bits (647), Expect = 8e-70
Identities = 146/354 (41%), Positives = 209/354 (59%), Gaps = 19/354 (5%)
Query: 396 CADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD 454
CA+ G CS +C+ +C C G+ D C E LLF+R+ DIR+ISL+
Sbjct: 592 CAEENGGCSHLCLYRPQGLRCACPIGFELIS-DMKTCIVPEAF--LLFSRRADIRRISLE 648
Query: 455 -HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
++ VAI + K A+ALD+ I+W+D++ + I +A ++ G+ V+ L
Sbjct: 649 TNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMN-GSALEHVVEFGLDYP 707
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
+G+AVDW+ +LYW DTG N IE+S L G R++L+ L+ PRA+AL+P EG+M+WT+W
Sbjct: 708 EGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEW 767
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G PKI+RA MDGS R+T+V +V NGLT+D ++R+YW D N I S N G R
Sbjct: 768 GGKPKIDRAAMDGSERTTLVP-NVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNRE 826
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I + L HPF +T ++D++YWTDW + ++ RANK +G++ I H L M I V
Sbjct: 827 VI---ADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQN-RTIIQGH-LDYVMDILV 881
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+H RQ G N CA+ NGHCSHLCL P G C CP L D++ C
Sbjct: 882 FHSSRQ-SGWNECASSNGHCSHLCLAVPVGG-----FVCGCPAHYSLNADNRTC 929
Score = 157 bits (381), Expect = 1e-37
Identities = 106/366 (28%), Positives = 179/366 (48%), Gaps = 22/366 (6%)
Query: 394 DECADP-GSCSQICINEK-GTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKI 451
+ECA G CS +C+ G F C C Y+ + +RT C A LLF++K I ++
Sbjct: 891 NECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRT-CSAPTTF--LLFSQKSAINRM 947
Query: 452 SLDHHE---MVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG-- 506
+D + ++ ++ ++ A+DY ++W D I KA D TVV+
Sbjct: 948 VIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 507 --EQL-ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ L I L++D ++YWT N I ++ L G ++++ + PRA+ +NP
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPE 1067
Query: 564 EGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTIS 622
+G+M++T+ + PKIERA +DG+ R + + P L LD +++W D+ + I
Sbjct: 1068 KGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIE 1127
Query: 623 SCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTH 682
S + G+ R++L + +L+ P +T FE+W+YW D + + + + G++
Sbjct: 1128 SSDLSGA-NRIVLEDSNILQ-PVGLTVFENWLYWIDKQQQMIEKID-MTGREGRTKVQAR 1184
Query: 683 TLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPD 742
Q + V Q + CA NG CSH+CL G + R C+CP L LL D
Sbjct: 1185 IAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVK---GDGTTR--CSCPMHLVLLQD 1239
Query: 743 DQMCVE 748
+ C E
Sbjct: 1240 ELSCGE 1245
Score = 103 bits (247), Expect = 2e-21
Identities = 56/129 (43%), Positives = 71/129 (55%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP++W+CD +C D SDE C VC E +F+C S
Sbjct: 1245 EPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDE--LNCP----VCSESQFQCAS- 1297
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G CI + RC+ A+C D SDE CEV C ++F C G+C+ CD N DCSD
Sbjct: 1298 GQCIDGALRCNGDANCQDKSDEKNCEV-LCLIDQFRCAN--GQCIGKHKKCDHNVDCSDK 1354
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1355 SDELDCYPT 1363
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/167 (32%), Positives = 72/167 (43%), Gaps = 13/167 (7%)
Query: 67 QEYR-FECLSDG-----LCIPR---SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGK 116
QEYR C D +C+ + + RC DE C E C P++FTC
Sbjct: 1200 QEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTG 1259
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
+C+P+ W CD +C D SDE C C +F C +G+CI
Sbjct: 1260 EIDCIPVAWRCDGFTECEDHSDELNC-PVCSESQFQCASGQCIDGALRCNGDANCQDKSD 1318
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVST 223
E C Q F C +GQCI CD +VDC+D SDE+ C T
Sbjct: 1319 EKNCEVLCLIDQ--FRCANGQCIGKHKKCDHNVDCSDKSDELDCYPT 1363
Score = 87.8 bits (208), Expect = 1e-16
Identities = 46/135 (34%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+C+
Sbjct: 1249 CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPV--CSESQFQCAS--GQCIDGA 1304
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT 184
C+ + +C D SDEK C C D+F C NG+CI E+ C PT
Sbjct: 1305 LRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDELDC-YPT 1363
Query: 185 CQPQSHFSCTDGQCI 199
+P + T G I
Sbjct: 1364 EEPAPQATNTVGSVI 1378
Score = 75.8 bits (178), Expect = 5e-13
Identities = 72/292 (24%), Positives = 125/292 (42%), Gaps = 18/292 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C + NGGCS C+ P G C C G++LI D +TC E + +I +
Sbjct: 588 GSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISL 647
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D T + SL + + +L+H +V D
Sbjct: 648 ETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEH--VVEFGLD 705
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I + +D G R V++ + L + LA+D +
Sbjct: 706 YPEGMAVDWLGKN--LYWADTGTNRIEVSKLD-GQHRQVLVWKDLDSPRALALDPAEGFM 762
Query: 525 YWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGM 583
YWT+ G I+ + + G+ R L+ + + ++ + ++WTD IE + M
Sbjct: 763 YWTEWGGKPKIDRAAMDGSERTTLV-PNVGRANGLTIDYAKRRLYWTDL-DTNLIESSNM 820
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
G +R +++ D+ P GLT + +YW D +I N R I+
Sbjct: 821 LGLNRE-VIADDLPHPFGLT--QYQDYIYWTDWSRRSIERANKTSGQNRTII 869
Score = 71.7 bits (168), Expect = 9e-12
Identities = 71/291 (24%), Positives = 125/291 (42%), Gaps = 19/291 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPI-GYYCDCEKGYKL-IDNRTCEDIDE---CADPGSCSQIC 406
G NEC +NG CS C+ P+ G+ C C Y L DNRTC + + +++
Sbjct: 889 GWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMV 948
Query: 407 INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHE-MVAIVNDT 465
I+E+ + R+ R + + +R++ IRK D + +V+
Sbjct: 949 IDEQQSPDIILPIHSLRNVR-AIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 466 KSATA------LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
S L + I+W+ I +D + V+ GEQ + V+
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAVVVNP 1066
Query: 520 VYNHLYWTDTGHN--HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
++Y+T+ IE + L G R++L L +P A+AL+ G +FW D + +
Sbjct: 1067 EKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWAD-SDLRR 1125
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
IE + + G++R + ++ P GLT + +YW+D + I + G
Sbjct: 1126 IESSDLSGANRIVLEDSNILQPVGLT--VFENWLYWIDKQQQMIEKIDMTG 1174
Score = 71.7 bits (168), Expect = 9e-12
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 216 DEVGCVSTPKVRSPCISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR 274
DE+ C P C +F C I C+ AW E C C
Sbjct: 1239 DELSCGEPPT----CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELN--CP---VCS 1289
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
QFQC CI GAL CNG +C D SDE NC + +C +F C G CI K C
Sbjct: 1290 ESQFQCASGQCIDGALRCNGDANCQDKSDEKNC---EVLC-LIDQFRCANGQCIGKHKKC 1345
Query: 335 DKHVDCPNFEDE 346
D +VDC + DE
Sbjct: 1346 DHNVDCSDKSDE 1357
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 177 EVKC-PTPTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCIST 233
E+ C PTC PQ F+C G+ CI W CDG +C D SDE+ C C +
Sbjct: 1240 ELSCGEPPTCSPQQ-FTCFTGEIDCIPVAWRCDGFTECEDHSDELNC-------PVCSES 1291
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCN 293
+F+C C+ A E + C V C +DQF+C + CI C+
Sbjct: 1292 QFQCASG-QCIDGALRCNGDANCQDKSDE--KNCE--VLCLIDQFRCANGQCIGKHKKCD 1346
Query: 294 GVKDCPDGSDEYNC 307
DC D SDE +C
Sbjct: 1347 HNVDCSDKSDELDC 1360
Score = 43.6 bits (98), Expect = 0.003
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIG--YYCDCEKGYKLIDN-RTCED 392
N C +NGGCS C+ +P+ Y C C G KL++N +TC+D
Sbjct: 284 NPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKD 325
>BC117136-1|AAI17137.1| 1613|Homo sapiens low density lipoprotein
receptor-related protein 6 protein.
Length = 1613
Score = 299 bits (735), Expect = 2e-80
Identities = 143/320 (44%), Positives = 201/320 (62%), Gaps = 14/320 (4%)
Query: 431 CKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRTGMIFWSDVNDE 488
C P LL+A + D+R + + + A +V + A A+D+VF G+I+WSDV++E
Sbjct: 14 CVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEE 73
Query: 489 KIYKAPID--EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKI 546
I + + E Q VV G L++ DGLA DW+ LYWTD+ N IE+S+L G++RK+
Sbjct: 74 AIKRTEFNKTESVQNVVVSG--LLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKV 131
Query: 547 LIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDL 606
L L++PRAIAL+P G+M+WTDWG+VPKIERAGMDGS R I++ ++ WPNGLTLD
Sbjct: 132 LFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDY 191
Query: 607 VRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYR 666
Q++YW DAK+N I N DG+ R+ ++ + L HPF++T FED +YWTDW ++
Sbjct: 192 EEQKLYWADAKLNFIHKSNLDGTNRQAVVKGS--LPHPFALTLFEDILYWTDWSTHSILA 249
Query: 667 ANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNS 726
NK+ G+ + I S + +PM IH + RQP+ N C NG CSHLCL P
Sbjct: 250 CNKYTGEGLREIHS--DIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCL----MSPVK 303
Query: 727 PRVSCACPNGLKLLPDDQMC 746
P CACP G+KLL + + C
Sbjct: 304 PFYQCACPTGVKLLENGKTC 323
Score = 272 bits (667), Expect = 3e-72
Identities = 149/357 (41%), Positives = 207/357 (57%), Gaps = 24/357 (6%)
Query: 398 DPGSCSQICINE--KGTFKCECHTGYARDPRDRTRCK--ATEGHPSLLFARKHDIRKISL 453
D G CS +C+ K ++C C TG +T CK ATE LL AR+ D+R+ISL
Sbjct: 289 DNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKT-CKDGATE---LLLLARRTDLRRISL 344
Query: 454 DHHEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLI 510
D + IV D + A A+DY G I+W+D I ++ ID G+ V+ Q+
Sbjct: 345 DTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFID-GSGSQFVVTAQIA 403
Query: 511 TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
DG+AVDWV +LYWTDTG + IE++ L G MRKILI + LEEPRAI L+P+ G+M+WT
Sbjct: 404 HPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWT 463
Query: 571 DWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSG 630
DWG++PKIERA +DGS R +V+ + WPNGL LD ++YW DAK + I N DG+G
Sbjct: 464 DWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTG 523
Query: 631 RRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVI 690
RR+++ + + H F T D+VYWTDW + ++ R +K + + I L
Sbjct: 524 RRVLVE--DKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKAT 581
Query: 691 HVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+V+ G N CA NG CSHLCL P+ + CACP G +L+ D + C+
Sbjct: 582 NVHRVI----GSNPCAEENGGCSHLCLYRPQ------GLRCACPIGFELISDMKTCI 628
Score = 264 bits (647), Expect = 8e-70
Identities = 146/354 (41%), Positives = 209/354 (59%), Gaps = 19/354 (5%)
Query: 396 CADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD 454
CA+ G CS +C+ +C C G+ D C E LLF+R+ DIR+ISL+
Sbjct: 592 CAEENGGCSHLCLYRPQGLRCACPIGFELIS-DMKTCIVPEAF--LLFSRRADIRRISLE 648
Query: 455 -HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
++ VAI + K A+ALD+ I+W+D++ + I +A ++ G+ V+ L
Sbjct: 649 TNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMN-GSALEHVVEFGLDYP 707
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
+G+AVDW+ +LYW DTG N IE+S L G R++L+ L+ PRA+AL+P EG+M+WT+W
Sbjct: 708 EGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEW 767
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G PKI+RA MDGS R+T+V +V NGLT+D ++R+YW D N I S N G R
Sbjct: 768 GGKPKIDRAAMDGSERTTLVP-NVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNRE 826
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I + L HPF +T ++D++YWTDW + ++ RANK +G++ I H L M I V
Sbjct: 827 VI---ADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQN-RTIIQGH-LDYVMDILV 881
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+H RQ G N CA+ NGHCSHLCL P G C CP L D++ C
Sbjct: 882 FHSSRQ-SGWNECASSNGHCSHLCLAVPVGG-----FVCGCPAHYSLNADNRTC 929
Score = 157 bits (381), Expect = 1e-37
Identities = 106/366 (28%), Positives = 179/366 (48%), Gaps = 22/366 (6%)
Query: 394 DECADP-GSCSQICINEK-GTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKI 451
+ECA G CS +C+ G F C C Y+ + +RT C A LLF++K I ++
Sbjct: 891 NECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRT-CSAPTTF--LLFSQKSAINRM 947
Query: 452 SLDHHE---MVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG-- 506
+D + ++ ++ ++ A+DY ++W D I KA D TVV+
Sbjct: 948 VIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 507 --EQL-ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ L I L++D ++YWT N I ++ L G ++++ + PRA+ +NP
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPE 1067
Query: 564 EGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTIS 622
+G+M++T+ + PKIERA +DG+ R + + P L LD +++W D+ + I
Sbjct: 1068 KGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIE 1127
Query: 623 SCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTH 682
S + G+ R++L + +L+ P +T FE+W+YW D + + + + G++
Sbjct: 1128 SSDLSGA-NRIVLEDSNILQ-PVGLTVFENWLYWIDKQQQMIEKID-MTGREGRTKVQAR 1184
Query: 683 TLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPD 742
Q + V Q + CA NG CSH+CL G + R C+CP L LL D
Sbjct: 1185 IAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVK---GDGTTR--CSCPMHLVLLQD 1239
Query: 743 DQMCVE 748
+ C E
Sbjct: 1240 ELSCGE 1245
Score = 103 bits (247), Expect = 2e-21
Identities = 56/129 (43%), Positives = 71/129 (55%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP++W+CD +C D SDE C VC E +F+C S
Sbjct: 1245 EPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDE--LNCP----VCSESQFQCAS- 1297
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G CI + RC+ A+C D SDE CEV C ++F C G+C+ CD N DCSD
Sbjct: 1298 GQCIDGALRCNGDANCQDKSDEKNCEV-LCLIDQFRCAN--GQCIGKHKKCDHNVDCSDK 1354
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1355 SDELDCYPT 1363
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/167 (32%), Positives = 72/167 (43%), Gaps = 13/167 (7%)
Query: 67 QEYR-FECLSDG-----LCIPR---SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGK 116
QEYR C D +C+ + + RC DE C E C P++FTC
Sbjct: 1200 QEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTG 1259
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
+C+P+ W CD +C D SDE C C +F C +G+CI
Sbjct: 1260 EIDCIPVAWRCDGFTECEDHSDELNC-PVCSESQFQCASGQCIDGALRCNGDANCQDKSD 1318
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVST 223
E C Q F C +GQCI CD +VDC+D SDE+ C T
Sbjct: 1319 EKNCEVLCLIDQ--FRCANGQCIGKHKKCDHNVDCSDKSDELDCYPT 1363
Score = 87.8 bits (208), Expect = 1e-16
Identities = 46/135 (34%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+C+
Sbjct: 1249 CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPV--CSESQFQCAS--GQCIDGA 1304
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT 184
C+ + +C D SDEK C C D+F C NG+CI E+ C PT
Sbjct: 1305 LRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDELDC-YPT 1363
Query: 185 CQPQSHFSCTDGQCI 199
+P + T G I
Sbjct: 1364 EEPAPQATNTVGSVI 1378
Score = 75.8 bits (178), Expect = 5e-13
Identities = 72/292 (24%), Positives = 125/292 (42%), Gaps = 18/292 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C + NGGCS C+ P G C C G++LI D +TC E + +I +
Sbjct: 588 GSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISL 647
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D T + SL + + +L+H +V D
Sbjct: 648 ETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEH--VVEFGLD 705
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I + +D G R V++ + L + LA+D +
Sbjct: 706 YPEGMAVDWLGKN--LYWADTGTNRIEVSKLD-GQHRQVLVWKDLDSPRALALDPAEGFM 762
Query: 525 YWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGM 583
YWT+ G I+ + + G+ R L+ + + ++ + ++WTD IE + M
Sbjct: 763 YWTEWGGKPKIDRAAMDGSERTTLV-PNVGRANGLTIDYAKRRLYWTDL-DTNLIESSNM 820
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
G +R +++ D+ P GLT + +YW D +I N R I+
Sbjct: 821 LGLNRE-VIADDLPHPFGLT--QYQDYIYWTDWSRRSIERANKTSGQNRTII 869
Score = 71.7 bits (168), Expect = 9e-12
Identities = 71/291 (24%), Positives = 125/291 (42%), Gaps = 19/291 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPI-GYYCDCEKGYKL-IDNRTCEDIDE---CADPGSCSQIC 406
G NEC +NG CS C+ P+ G+ C C Y L DNRTC + + +++
Sbjct: 889 GWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMV 948
Query: 407 INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHE-MVAIVNDT 465
I+E+ + R+ R + + +R++ IRK D + +V+
Sbjct: 949 IDEQQSPDIILPIHSLRNVR-AIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 466 KSATA------LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
S L + I+W+ I +D + V+ GEQ + V+
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAVVVNP 1066
Query: 520 VYNHLYWTDTGHN--HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
++Y+T+ IE + L G R++L L +P A+AL+ G +FW D + +
Sbjct: 1067 EKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWAD-SDLRR 1125
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
IE + + G++R + ++ P GLT + +YW+D + I + G
Sbjct: 1126 IESSDLSGANRIVLEDSNILQPVGLT--VFENWLYWIDKQQQMIEKIDMTG 1174
Score = 71.7 bits (168), Expect = 9e-12
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 216 DEVGCVSTPKVRSPCISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR 274
DE+ C P C +F C I C+ AW E C C
Sbjct: 1239 DELSCGEPPT----CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELN--CP---VCS 1289
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
QFQC CI GAL CNG +C D SDE NC + +C +F C G CI K C
Sbjct: 1290 ESQFQCASGQCIDGALRCNGDANCQDKSDEKNC---EVLC-LIDQFRCANGQCIGKHKKC 1345
Query: 335 DKHVDCPNFEDE 346
D +VDC + DE
Sbjct: 1346 DHNVDCSDKSDE 1357
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 177 EVKC-PTPTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCIST 233
E+ C PTC PQ F+C G+ CI W CDG +C D SDE+ C C +
Sbjct: 1240 ELSCGEPPTCSPQQ-FTCFTGEIDCIPVAWRCDGFTECEDHSDELNC-------PVCSES 1291
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCN 293
+F+C C+ A E + C V C +DQF+C + CI C+
Sbjct: 1292 QFQCASG-QCIDGALRCNGDANCQDKSDE--KNCE--VLCLIDQFRCANGQCIGKHKKCD 1346
Query: 294 GVKDCPDGSDEYNC 307
DC D SDE +C
Sbjct: 1347 HNVDCSDKSDELDC 1360
Score = 43.6 bits (98), Expect = 0.003
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIG--YYCDCEKGYKLIDN-RTCED 392
N C +NGGCS C+ +P+ Y C C G KL++N +TC+D
Sbjct: 284 NPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKD 325
>AF074264-1|AAC33006.1| 1613|Homo sapiens LDL receptor-related
protein 6 protein.
Length = 1613
Score = 299 bits (735), Expect = 2e-80
Identities = 143/320 (44%), Positives = 201/320 (62%), Gaps = 14/320 (4%)
Query: 431 CKATEGHPSLLFARKHDIRKISLDHHEMVA--IVNDTKSATALDYVFRTGMIFWSDVNDE 488
C P LL+A + D+R + + + A +V + A A+D+VF G+I+WSDV++E
Sbjct: 14 CVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEE 73
Query: 489 KIYKAPID--EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKI 546
I + + E Q VV G L++ DGLA DW+ LYWTD+ N IE+S+L G++RK+
Sbjct: 74 AIKRTEFNKTESVQNVVVSG--LLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKV 131
Query: 547 LIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDL 606
L L++PRAIAL+P G+M+WTDWG+VPKIERAGMDGS R I++ ++ WPNGLTLD
Sbjct: 132 LFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDY 191
Query: 607 VRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYR 666
Q++YW DAK+N I N DG+ R+ ++ + L HPF++T FED +YWTDW ++
Sbjct: 192 EEQKLYWADAKLNFIHKSNLDGTNRQAVVKGS--LPHPFALTLFEDILYWTDWSTHSILA 249
Query: 667 ANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNS 726
NK+ G+ + I S + +PM IH + RQP+ N C NG CSHLCL P
Sbjct: 250 CNKYTGEGLREIHS--DIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCL----MSPVK 303
Query: 727 PRVSCACPNGLKLLPDDQMC 746
P CACP G+KLL + + C
Sbjct: 304 PFYQCACPTGVKLLENGKTC 323
Score = 272 bits (667), Expect = 3e-72
Identities = 149/357 (41%), Positives = 207/357 (57%), Gaps = 24/357 (6%)
Query: 398 DPGSCSQICINE--KGTFKCECHTGYARDPRDRTRCK--ATEGHPSLLFARKHDIRKISL 453
D G CS +C+ K ++C C TG +T CK ATE LL AR+ D+R+ISL
Sbjct: 289 DNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKT-CKDGATE---LLLLARRTDLRRISL 344
Query: 454 DHHEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLI 510
D + IV D + A A+DY G I+W+D I ++ ID G+ V+ Q+
Sbjct: 345 DTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFID-GSGSQFVVTAQIA 403
Query: 511 TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
DG+AVDWV +LYWTDTG + IE++ L G MRKILI + LEEPRAI L+P+ G+M+WT
Sbjct: 404 HPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWT 463
Query: 571 DWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSG 630
DWG++PKIERA +DGS R +V+ + WPNGL LD ++YW DAK + I N DG+G
Sbjct: 464 DWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTG 523
Query: 631 RRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVI 690
RR+++ + + H F T D+VYWTDW + ++ R +K + + I L
Sbjct: 524 RRVLVE--DKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKAT 581
Query: 691 HVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+V+ G N CA NG CSHLCL P+ + CACP G +L+ D + C+
Sbjct: 582 NVHRVI----GSNPCAEENGGCSHLCLYRPQ------GLRCACPIGFELISDMKTCI 628
Score = 264 bits (647), Expect = 8e-70
Identities = 146/354 (41%), Positives = 209/354 (59%), Gaps = 19/354 (5%)
Query: 396 CADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD 454
CA+ G CS +C+ +C C G+ D C E LLF+R+ DIR+ISL+
Sbjct: 592 CAEENGGCSHLCLYRPQGLRCACPIGFELIS-DMKTCIVPEAF--LLFSRRADIRRISLE 648
Query: 455 -HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
++ VAI + K A+ALD+ I+W+D++ + I +A ++ G+ V+ L
Sbjct: 649 TNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMN-GSALEHVVEFGLDYP 707
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
+G+AVDW+ +LYW DTG N IE+S L G R++L+ L+ PRA+AL+P EG+M+WT+W
Sbjct: 708 EGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEW 767
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G PKI+RA MDGS R+T+V +V NGLT+D ++R+YW D N I S N G R
Sbjct: 768 GGKPKIDRAAMDGSERTTLVP-NVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNRE 826
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I + L HPF +T ++D++YWTDW + ++ RANK +G++ I H L M I V
Sbjct: 827 VI---ADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQN-RTIIQGH-LDYVMDILV 881
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+H RQ G N CA+ NGHCSHLCL P G C CP L D++ C
Sbjct: 882 FHSSRQ-SGWNECASSNGHCSHLCLAVPVGG-----FVCGCPAHYSLNADNRTC 929
Score = 157 bits (382), Expect = 1e-37
Identities = 107/366 (29%), Positives = 179/366 (48%), Gaps = 22/366 (6%)
Query: 394 DECADP-GSCSQICINEK-GTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKI 451
+ECA G CS +C+ G F C C Y+ + +RT C A LLF++K I ++
Sbjct: 891 NECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRT-CSAPTTF--LLFSQKSAINRM 947
Query: 452 SLDHHE---MVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG-- 506
+D + ++ ++ ++ A+DY ++W D I KA D TVV+
Sbjct: 948 VIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 507 --EQL-ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ L I L++D ++YWT N I ++ L G ++++ + PRAI +NP
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAIVVNPE 1067
Query: 564 EGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTIS 622
+G+M++T+ + PKIERA +DG+ R + + P L LD +++W D+ + I
Sbjct: 1068 KGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIE 1127
Query: 623 SCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTH 682
S + G+ R++L + +L+ P +T FE+W+YW D + + + + G++
Sbjct: 1128 SSDLSGA-NRIVLEDSNILQ-PVGLTVFENWLYWIDKQQQMIEKID-MTGREGRTKVQAR 1184
Query: 683 TLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPD 742
Q + V Q + CA NG CSH+CL G + R C+CP L LL D
Sbjct: 1185 IAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVK---GDGTTR--CSCPMHLVLLQD 1239
Query: 743 DQMCVE 748
+ C E
Sbjct: 1240 ELSCGE 1245
Score = 103 bits (247), Expect = 2e-21
Identities = 56/129 (43%), Positives = 71/129 (55%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP++W+CD +C D SDE C VC E +F+C S
Sbjct: 1245 EPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDE--LNCP----VCSESQFQCAS- 1297
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G CI + RC+ A+C D SDE CEV C ++F C G+C+ CD N DCSD
Sbjct: 1298 GQCIDGALRCNGDANCQDKSDEKNCEV-LCLIDQFRCAN--GQCIGKHKKCDHNVDCSDK 1354
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1355 SDELDCYPT 1363
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/167 (32%), Positives = 72/167 (43%), Gaps = 13/167 (7%)
Query: 67 QEYR-FECLSDG-----LCIPR---SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGK 116
QEYR C D +C+ + + RC DE C E C P++FTC
Sbjct: 1200 QEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTG 1259
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
+C+P+ W CD +C D SDE C C +F C +G+CI
Sbjct: 1260 EIDCIPVAWRCDGFTECEDHSDELNC-PVCSESQFQCASGQCIDGALRCNGDANCQDKSD 1318
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVST 223
E C Q F C +GQCI CD +VDC+D SDE+ C T
Sbjct: 1319 EKNCEVLCLIDQ--FRCANGQCIGKHKKCDHNVDCSDKSDELDCYPT 1363
Score = 87.8 bits (208), Expect = 1e-16
Identities = 46/135 (34%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+C+
Sbjct: 1249 CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPV--CSESQFQCAS--GQCIDGA 1304
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT 184
C+ + +C D SDEK C C D+F C NG+CI E+ C PT
Sbjct: 1305 LRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDELDC-YPT 1363
Query: 185 CQPQSHFSCTDGQCI 199
+P + T G I
Sbjct: 1364 EEPAPQATNTVGSVI 1378
Score = 75.8 bits (178), Expect = 5e-13
Identities = 72/292 (24%), Positives = 125/292 (42%), Gaps = 18/292 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C + NGGCS C+ P G C C G++LI D +TC E + +I +
Sbjct: 588 GSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISL 647
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D T + SL + + +L+H +V D
Sbjct: 648 ETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEH--VVEFGLD 705
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I + +D G R V++ + L + LA+D +
Sbjct: 706 YPEGMAVDWLGKN--LYWADTGTNRIEVSKLD-GQHRQVLVWKDLDSPRALALDPAEGFM 762
Query: 525 YWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGM 583
YWT+ G I+ + + G+ R L+ + + ++ + ++WTD IE + M
Sbjct: 763 YWTEWGGKPKIDRAAMDGSERTTLV-PNVGRANGLTIDYAKRRLYWTDL-DTNLIESSNM 820
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
G +R +++ D+ P GLT + +YW D +I N R I+
Sbjct: 821 LGLNRE-VIADDLPHPFGLT--QYQDYIYWTDWSRRSIERANKTSGQNRTII 869
Score = 72.1 bits (169), Expect = 7e-12
Identities = 71/291 (24%), Positives = 125/291 (42%), Gaps = 19/291 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPI-GYYCDCEKGYKL-IDNRTCEDIDE---CADPGSCSQIC 406
G NEC +NG CS C+ P+ G+ C C Y L DNRTC + + +++
Sbjct: 889 GWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMV 948
Query: 407 INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHE-MVAIVNDT 465
I+E+ + R+ R + + +R++ IRK D + +V+
Sbjct: 949 IDEQQSPDIILPIHSLRNVR-AIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 1007
Query: 466 KSATA------LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
S L + I+W+ I +D + V+ GEQ + V+
Sbjct: 1008 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAIVVNP 1066
Query: 520 VYNHLYWTDTGHN--HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
++Y+T+ IE + L G R++L L +P A+AL+ G +FW D + +
Sbjct: 1067 EKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWAD-SDLRR 1125
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
IE + + G++R + ++ P GLT + +YW+D + I + G
Sbjct: 1126 IESSDLSGANRIVLEDSNILQPVGLT--VFENWLYWIDKQQQMIEKIDMTG 1174
Score = 71.7 bits (168), Expect = 9e-12
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 216 DEVGCVSTPKVRSPCISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR 274
DE+ C P C +F C I C+ AW E C C
Sbjct: 1239 DELSCGEPPT----CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELN--CP---VCS 1289
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
QFQC CI GAL CNG +C D SDE NC + +C +F C G CI K C
Sbjct: 1290 ESQFQCASGQCIDGALRCNGDANCQDKSDEKNC---EVLC-LIDQFRCANGQCIGKHKKC 1345
Query: 335 DKHVDCPNFEDE 346
D +VDC + DE
Sbjct: 1346 DHNVDCSDKSDE 1357
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 177 EVKC-PTPTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCIST 233
E+ C PTC PQ F+C G+ CI W CDG +C D SDE+ C C +
Sbjct: 1240 ELSCGEPPTCSPQQ-FTCFTGEIDCIPVAWRCDGFTECEDHSDELNC-------PVCSES 1291
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCN 293
+F+C C+ A E + C V C +DQF+C + CI C+
Sbjct: 1292 QFQCASG-QCIDGALRCNGDANCQDKSDE--KNCE--VLCLIDQFRCANGQCIGKHKKCD 1346
Query: 294 GVKDCPDGSDEYNC 307
DC D SDE +C
Sbjct: 1347 HNVDCSDKSDELDC 1360
Score = 43.6 bits (98), Expect = 0.003
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIG--YYCDCEKGYKLIDN-RTCED 392
N C +NGGCS C+ +P+ Y C C G KL++N +TC+D
Sbjct: 284 NPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKD 325
>X55077-1|CAA38905.1| 591|Homo sapiens alpha-2 macroglobulin
receptor protein.
Length = 591
Score = 282 bits (691), Expect = 4e-75
Identities = 159/425 (37%), Positives = 197/425 (46%), Gaps = 27/425 (6%)
Query: 22 TCTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
TC ++F+C T RCIP W CD + DC D SDE P CT +M C F C G CI
Sbjct: 178 TCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE-PANCT--QMTCGVDEFRCKDSGRCI 234
Query: 81 PRSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
P W+CD DC DGSDE +C+ C P +F C K CVP W CD + DC D SD
Sbjct: 235 PARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRC--KNNRCVPGRWQCDYDNDCGDNSD 292
Query: 139 EKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQ 197
E++C C EF+C NG+CI RW E C TP C F C G
Sbjct: 293 EESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-TPRCD-MDQFQCKSGH 350
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
CI W CD D DC DGSDE C + VR+ C EF+CN+ + C AW
Sbjct: 351 CIPLRWRCDADADCMDGSDEEACGT--GVRT-CPLDEFQCNNTL-CKPLAWKCDGEDDCG 406
Query: 258 XXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNC---TRQKTI 313
E E C V F+CK D C+ C+G +C DG+DE +C T T
Sbjct: 407 DNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 466
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQ--RCVD 369
C + EF C C+ S C+ DC + DE C N C RCV
Sbjct: 467 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 526
Query: 370 TPIGYYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDR 428
T YC C G+ + + C+DI+EC G+CSQ+C N KG C C + +
Sbjct: 527 TEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFM---KTH 583
Query: 429 TRCKA 433
CKA
Sbjct: 584 NTCKA 588
Score = 229 bits (561), Expect = 2e-59
Identities = 139/392 (35%), Positives = 182/392 (46%), Gaps = 29/392 (7%)
Query: 14 FFLFSESRTC----TSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY 69
F+L S+ RTC T+S+F CK +CIP WKCD E DC D SDE P C K C+
Sbjct: 47 FYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPD-CPEFK--CRPG 103
Query: 70 RFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
+F+C S G+C ++ CD DC D SDE C++ C P +F C C+P + C+
Sbjct: 104 QFQC-STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCT-NTNRCIPGIFRCNG 161
Query: 130 NPDCSDGSDEKACNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXE-VKCPTPTCQ 186
+C DG DE+ C E TC ++F C +CI WV E C TC
Sbjct: 162 QDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTC- 220
Query: 187 PQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVH 245
F C D G+CI A W CDG+ DC DGSDE + C +F C + CV
Sbjct: 221 GVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERT---CEPYQFRCKNN-RCVP 276
Query: 246 RAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY 305
W E E C C +F C + CI G C+G DC DGSDE
Sbjct: 277 GRWQCDYDNDCGDNSDE--ESCTPR-PCSESEFSCANGRCIAGRWKCDGDHDCADGSDEK 333
Query: 306 NCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+CT + CD +F C G CIPL CD DC + DE G C + C+
Sbjct: 334 DCTPR---CD-MDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCN- 388
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
+ P+ + CD E + + E+ +ECA
Sbjct: 389 NTLCKPLAWKCDGEDD---CGDNSDENPEECA 417
Score = 111 bits (267), Expect = 9e-24
Identities = 57/153 (37%), Positives = 82/153 (53%), Gaps = 17/153 (11%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLC 79
RTC EF+C C PL+WKCD E DC D+SDE+P C + VC R F C +D +C
Sbjct: 378 RTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEEC--ARFVCPPNRPFRCKNDRVC 435
Query: 80 IPRSWRCDATADCPDGSDEHQCE------VEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
+ +CD T +C DG+DE CE +EF CR + C+ + C+ DC
Sbjct: 436 LWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ--RCLSSSLRCNMFDDC 493
Query: 134 SDGSDEKACN-----ETCRSDEFTCGN-GKCIQ 160
DGSDE+ C+ +C ++ CG+ +C++
Sbjct: 494 GDGSDEEDCSIDPKLTSCATNASICGDEARCVR 526
Score = 56.0 bits (129), Expect = 5e-07
Identities = 29/64 (45%), Positives = 35/64 (54%), Gaps = 6/64 (9%)
Query: 687 PMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQM 745
PM +HV+H RQPD NH C NG CS+LCL +P G CACP L D +
Sbjct: 1 PMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGH-----KCACPTNFYLGSDGRT 55
Query: 746 CVED 749
CV +
Sbjct: 56 CVSN 59
Score = 37.1 bits (82), Expect = 0.23
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 356 CEKNNGGCSQRCVDTP-IGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEK 410
C+ NNGGCS C+ +P G+ C C + L D RTC + C + +C N+K
Sbjct: 20 CKVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTC--VSNCT---ASQFVCKNDK 71
>AF283321-1|AAK52433.1| 1611|Homo sapiens low density lipoprotein
receptor-related protein 5 protein.
Length = 1611
Score = 272 bits (667), Expect = 3e-72
Identities = 134/314 (42%), Positives = 190/314 (60%), Gaps = 15/314 (4%)
Query: 438 PSLLFARKHDIRKISLD--HHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
P LLFA + D+R + E +V+ + A A+D+ F G ++W+DV++E I + +
Sbjct: 33 PLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYL 92
Query: 496 DE---GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRL 552
++ Q V+ G L++ DGLA DWV LYWTD+ N IE+++L G RK+L L
Sbjct: 93 NQTGAAVQNVVISG--LVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDL 150
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVY 612
++PRAIAL+P G+M+WTDWG+ P+IERAGMDGS R IV D+ WPNGLT+DL Q++Y
Sbjct: 151 DQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLY 210
Query: 613 WVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNG 672
W DAK++ I N DGS R+ ++ + L HPF++T D +YWTDW +++ NK G
Sbjct: 211 WADAKLSFIHRANLDGSFRQKVVEGS--LTHPFALTLSGDTLYWTDWQTRSIHACNKRTG 268
Query: 673 KDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCA 732
+ I S L +PM I V RQP C NG CSHLCL P+ P +CA
Sbjct: 269 GKRKEILS--ALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCL----LSPSEPFYTCA 322
Query: 733 CPNGLKLLPDDQMC 746
CP G++L + + C
Sbjct: 323 CPTGVQLQDNGRTC 336
Score = 263 bits (645), Expect = 1e-69
Identities = 143/355 (40%), Positives = 199/355 (56%), Gaps = 20/355 (5%)
Query: 398 DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH 455
D G CS +C+ + C C TG RT CKA LL AR+ D+R+ISLD
Sbjct: 302 DNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRT-CKAG-AEEVLLLARRTDLRRISLDT 359
Query: 456 HEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
+ IV +D + A A+DY G ++W+D I +A +D G+ ++ ++
Sbjct: 360 PDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLD-GSGAQTLVNTEINDP 418
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
DG+AVDWV +LYWTDTG + IE++ L G RKIL+ + L+EPRAIAL+P+ G M+WTDW
Sbjct: 419 DGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDW 478
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G+ PKIE A +DG R +V+ + WPNGL LDL ++YW DAK + I N DG+ RR
Sbjct: 479 GENPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRR 538
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+L + L H F T D++YWTDW + ++ R +K I L ++V
Sbjct: 539 TLLE--DKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNV 596
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+ G N CA NG CSHLC F P++ R C CP GL+LL D + C+
Sbjct: 597 ----AKVVGTNPCADRNGGCSHLCF----FTPHATR--CGCPIGLELLSDMKTCI 641
Score = 217 bits (530), Expect = 1e-55
Identities = 133/369 (36%), Positives = 199/369 (53%), Gaps = 20/369 (5%)
Query: 381 GYKLIDNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS 439
G K ++ + CAD G CS +C +C C G D C E
Sbjct: 590 GLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLEL-LSDMKTCIVPEAF-- 646
Query: 440 LLFARKHDIRKISLD-HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
L+F + I +ISL+ ++ VAI + K A+ALD+ I+W+DV+ + I +A ++
Sbjct: 647 LVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMN- 705
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
G+ V+ L +G+AVDW+ +LYW DTG N IE++ L G R++L+ L+ PR+
Sbjct: 706 GSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRS 765
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
+AL+P +G+++WT+WG P+I RA MDG++ T+V V N LT+D QR+YW D
Sbjct: 766 LALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVD-KVGRANDLTIDYADQRLYWTDLD 824
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
N I S N G R +I + L HPF +T + D++YWTDW+ ++ RA+K +G++
Sbjct: 825 TNMIESSNMLGQERVVI---ADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRN-RT 880
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ H L M I V+H RQ DG+N C NG C LCL P G + C C +
Sbjct: 881 LIQGH-LDFVMDILVFHSSRQ-DGLNDCMHNNGQCGQLCLAIP--GGH----RCGCASHY 932
Query: 738 KLLPDDQMC 746
L P + C
Sbjct: 933 TLDPSSRNC 941
Score = 142 bits (343), Expect = 6e-33
Identities = 107/369 (28%), Positives = 174/369 (47%), Gaps = 25/369 (6%)
Query: 391 EDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI- 448
+ +++C + G C Q+C+ G +C C + Y DP R T LLF++K I
Sbjct: 901 DGLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTT---FLLFSQKSAIS 957
Query: 449 RKISLDHH--EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG 506
R I D H +++ ++ ++ A+DY I+W D + I +A D+GTQ V+
Sbjct: 958 RMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVD-GRQNIKRAK-DDGTQPFVLTS 1015
Query: 507 -EQLITSD----GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALN 561
Q D L++D L+WT N I + L G +++R ++PRAI +N
Sbjct: 1016 LSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVN 1075
Query: 562 PLEGWMFWTDW-GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT 620
G++++T+ + KIERA +DG+ R + + + P L +D +++WVDA +
Sbjct: 1076 AERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKR 1135
Query: 621 ISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITS 680
I SC+ G+ RL L +++ P +T +YW D + + R K G I
Sbjct: 1136 IESCDLSGA-NRLTLEDANIVQ-PLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQG 1193
Query: 681 THTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKL 739
+ + IH + H CA NG CSH+C+ G +PR C+CP L L
Sbjct: 1194 --RVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAK---GDGTPR--CSCPVHLVL 1246
Query: 740 LPDDQMCVE 748
L + C E
Sbjct: 1247 LQNLLTCGE 1255
Score = 106 bits (254), Expect = 3e-22
Identities = 55/129 (42%), Positives = 68/129 (52%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP +W+CD +C D SDE+ C VC +F C +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEG--CP----VCSAAQFPC-AR 1307
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G C+ RCD ADC D SDE C+ C P +F C G+CV + CD PDC DG
Sbjct: 1308 GQCVDLRLRCDGEADCQDRSDEADCDA-ICLPNQFRCAS--GQCVLIKQQCDSFPDCIDG 1364
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1365 SDELMCEIT 1373
Score = 100 bits (239), Expect = 2e-20
Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 24/339 (7%)
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
TR C+KRT GG + +D E R CE++NGGCS C
Sbjct: 257 TRSIHACNKRT-----GGKRKEILSALYSPMDIQVLSQE-RQPFFHTRCEEDNGGCSHLC 310
Query: 368 VDTPIG--YYCDCEKGYKLIDN-RTC----EDIDECADPGSCSQICINEKGTFKCECHTG 420
+ +P Y C C G +L DN RTC E++ A +I ++
Sbjct: 311 LLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVD 370
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN---DTKSATALDYVFRT 477
R EG+ IR+ LD +VN + A+D+V R
Sbjct: 371 DIRH-AIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARN 429
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIEL 536
++W+D ++I ++ GT R +++ E L +A+ V +YWTD G N IE
Sbjct: 430 --LYWTDTGTDRIEVTRLN-GTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIEC 486
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDV 596
++L G R++L+ L P +AL+ EG ++W D + KIE +DG+ R T++ +
Sbjct: 487 ANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGD-AKTDKIEVINVDGTKRRTLL--ED 543
Query: 597 KWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
K P+ L+ +YW D + +I + + R +I+
Sbjct: 544 KLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVII 582
Score = 95.1 bits (226), Expect = 8e-19
Identities = 47/134 (35%), Positives = 62/134 (46%), Gaps = 5/134 (3%)
Query: 102 EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQM 161
E C P++F C +C+P W CD P+C D SDE+ C C + +F C G+C+ +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGC-PVCSAAQFPCARGQCVDL 1313
Query: 162 RWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCV 221
R E C C P + F C GQC+ CD DC DGSDE+ C
Sbjct: 1314 RLRCDGEADCQDRSDEADCDA-ICLP-NQFRCASGQCVLIKQQCDSFPDCIDGSDELMCE 1371
Query: 222 ST--PKVRSPCIST 233
T P SP S+
Sbjct: 1372 ITKPPSDDSPAHSS 1385
Score = 86.2 bits (204), Expect = 4e-16
Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+CV L
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPV--CSAAQFPCAR--GQCVDLR 1314
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR 162
CD DC D SDE C+ C ++F C +G+C+ ++
Sbjct: 1315 LRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIK 1352
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/291 (23%), Positives = 117/291 (40%), Gaps = 17/291 (5%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C NGGCS C TP C C G +L+ D +TC E + +I +
Sbjct: 601 GTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISL 660
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D + SL + + S++H +V D
Sbjct: 661 ETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEH--VVEFGLD 718
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I A +D G R V++ L LA+D ++
Sbjct: 719 YPEGMAVDWMGKN--LYWADTGTNRIEVARLD-GQFRQVLVWRDLDNPRSLALDPTKGYI 775
Query: 525 YWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMD 584
YWT+ G + + + D++ + ++ + ++WTD IE + M
Sbjct: 776 YWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDL-DTNMIESSNML 834
Query: 585 GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLI 634
G R +++ D+ P GLT +YW D +++I + G R LI
Sbjct: 835 GQER-VVIADDLPHPFGLT--QYSDYIYWTDWNLHSIERADKTSGRNRTLI 882
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/140 (32%), Positives = 56/140 (40%), Gaps = 25/140 (17%)
Query: 183 PTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGC-----VSTPKVRSPCISTEF 235
PTC P F+C G+ CI W CDG +C D SDE GC P R C+
Sbjct: 1257 PTCSPDQ-FACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRL 1315
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C+ C R+ EA C + C +QF+C C+ C+
Sbjct: 1316 RCDGEADCQDRS-------------DEAD--C--DAICLPNQFRCASGQCVLIKQQCDSF 1358
Query: 296 KDCPDGSDEYNCTRQKTICD 315
DC DGSDE C K D
Sbjct: 1359 PDCIDGSDELMCEITKPPSD 1378
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 230 CISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPG 288
C +F C I C+ AW E G C QF C C+
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDE-----EGCPVCSAAQFPCARGQCVDL 1313
Query: 289 ALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
L C+G DC D SDE +C IC +F C G C+ + + CD DC + DE
Sbjct: 1314 RLRCDGEADCQDRSDEADC---DAIC-LPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 38.7 bits (86), Expect = 0.076
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
G N+C NNG C Q C+ P G+ C C Y L +R C
Sbjct: 902 GLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNC 941
>AF077820-1|AAC72791.1| 1615|Homo sapiens LDL receptor member LR3
protein.
Length = 1615
Score = 272 bits (667), Expect = 3e-72
Identities = 134/314 (42%), Positives = 190/314 (60%), Gaps = 15/314 (4%)
Query: 438 PSLLFARKHDIRKISLD--HHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
P LLFA + D+R + E +V+ + A A+D+ F G ++W+DV++E I + +
Sbjct: 33 PLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYL 92
Query: 496 DE---GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRL 552
++ Q V+ G L++ DGLA DWV LYWTD+ N IE+++L G RK+L L
Sbjct: 93 NQTGAAVQNVVISG--LVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDL 150
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVY 612
++PRAIAL+P G+M+WTDWG+ P+IERAGMDGS R IV D+ WPNGLT+DL Q++Y
Sbjct: 151 DQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLY 210
Query: 613 WVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNG 672
W DAK++ I N DGS R+ ++ + L HPF++T D +YWTDW +++ NK G
Sbjct: 211 WADAKLSFIHRANLDGSFRQKVVEGS--LTHPFALTLSGDTLYWTDWQTRSIHACNKRTG 268
Query: 673 KDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCA 732
+ I S L +PM I V RQP C NG CSHLCL P+ P +CA
Sbjct: 269 GKRKEILS--ALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCL----LSPSEPFYTCA 322
Query: 733 CPNGLKLLPDDQMC 746
CP G++L + + C
Sbjct: 323 CPTGVQLQDNGRTC 336
Score = 263 bits (645), Expect = 1e-69
Identities = 143/355 (40%), Positives = 199/355 (56%), Gaps = 20/355 (5%)
Query: 398 DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH 455
D G CS +C+ + C C TG RT CKA LL AR+ D+R+ISLD
Sbjct: 302 DNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRT-CKAG-AEEVLLLARRTDLRRISLDT 359
Query: 456 HEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
+ IV +D + A A+DY G ++W+D I +A +D G+ ++ ++
Sbjct: 360 PDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLD-GSGAQTLVNTEINDP 418
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
DG+AVDWV +LYWTDTG + IE++ L G RKIL+ + L+EPRAIAL+P+ G M+WTDW
Sbjct: 419 DGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDW 478
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G+ PKIE A +DG R +V+ + WPNGL LDL ++YW DAK + I N DG+ RR
Sbjct: 479 GENPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRR 538
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+L + L H F T D++YWTDW + ++ R +K I L ++V
Sbjct: 539 TLLE--DKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNV 596
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+ G N CA NG CSHLC F P++ R C CP GL+LL D + C+
Sbjct: 597 ----AKVVGTNPCADRNGGCSHLCF----FTPHATR--CGCPIGLELLSDMKTCI 641
Score = 217 bits (530), Expect = 1e-55
Identities = 133/369 (36%), Positives = 199/369 (53%), Gaps = 20/369 (5%)
Query: 381 GYKLIDNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS 439
G K ++ + CAD G CS +C +C C G D C E
Sbjct: 590 GLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLEL-LSDMKTCIVPEAF-- 646
Query: 440 LLFARKHDIRKISLD-HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
L+F + I +ISL+ ++ VAI + K A+ALD+ I+W+DV+ + I +A ++
Sbjct: 647 LVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMN- 705
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
G+ V+ L +G+AVDW+ +LYW DTG N IE++ L G R++L+ L+ PR+
Sbjct: 706 GSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRS 765
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
+AL+P +G+++WT+WG P+I RA MDG++ T+V V N LT+D QR+YW D
Sbjct: 766 LALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVD-KVGRANDLTIDYADQRLYWTDLD 824
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
N I S N G R +I + L HPF +T + D++YWTDW+ ++ RA+K +G++
Sbjct: 825 TNMIESSNMLGQERVVI---ADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRN-RT 880
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ H L M I V+H RQ DG+N C NG C LCL P G + C C +
Sbjct: 881 LIQGH-LDFVMDILVFHSSRQ-DGLNDCMHNNGQCGQLCLAIP--GGH----RCGCASHY 932
Query: 738 KLLPDDQMC 746
L P + C
Sbjct: 933 TLDPSSRNC 941
Score = 142 bits (343), Expect = 6e-33
Identities = 107/369 (28%), Positives = 174/369 (47%), Gaps = 25/369 (6%)
Query: 391 EDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI- 448
+ +++C + G C Q+C+ G +C C + Y DP R T LLF++K I
Sbjct: 901 DGLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTT---FLLFSQKSAIS 957
Query: 449 RKISLDHH--EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG 506
R I D H +++ ++ ++ A+DY I+W D + I +A D+GTQ V+
Sbjct: 958 RMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVD-GRQNIKRAK-DDGTQPFVLTS 1015
Query: 507 -EQLITSD----GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALN 561
Q D L++D L+WT N I + L G +++R ++PRAI +N
Sbjct: 1016 LSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVN 1075
Query: 562 PLEGWMFWTDW-GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT 620
G++++T+ + KIERA +DG+ R + + + P L +D +++WVDA +
Sbjct: 1076 AERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKR 1135
Query: 621 ISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITS 680
I SC+ G+ RL L +++ P +T +YW D + + R K G I
Sbjct: 1136 IESCDLSGA-NRLTLEDANIVQ-PLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQG 1193
Query: 681 THTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKL 739
+ + IH + H CA NG CSH+C+ G +PR C+CP L L
Sbjct: 1194 --RVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAK---GDGTPR--CSCPVHLVL 1246
Query: 740 LPDDQMCVE 748
L + C E
Sbjct: 1247 LQNLLTCGE 1255
Score = 106 bits (254), Expect = 3e-22
Identities = 55/129 (42%), Positives = 68/129 (52%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP +W+CD +C D SDE+ C VC +F C +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEG--CP----VCSAAQFPC-AR 1307
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G C+ RCD ADC D SDE C+ C P +F C G+CV + CD PDC DG
Sbjct: 1308 GQCVDLRLRCDGEADCQDRSDEADCDA-ICLPNQFRCAS--GQCVLIKQQCDSFPDCIDG 1364
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1365 SDELMCEIT 1373
Score = 100 bits (239), Expect = 2e-20
Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 24/339 (7%)
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
TR C+KRT GG + +D E R CE++NGGCS C
Sbjct: 257 TRSIHACNKRT-----GGKRKEILSALYSPMDIQVLSQE-RQPFFHTRCEEDNGGCSHLC 310
Query: 368 VDTPIG--YYCDCEKGYKLIDN-RTC----EDIDECADPGSCSQICINEKGTFKCECHTG 420
+ +P Y C C G +L DN RTC E++ A +I ++
Sbjct: 311 LLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVD 370
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN---DTKSATALDYVFRT 477
R EG+ IR+ LD +VN + A+D+V R
Sbjct: 371 DIRH-AIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARN 429
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIEL 536
++W+D ++I ++ GT R +++ E L +A+ V +YWTD G N IE
Sbjct: 430 --LYWTDTGTDRIEVTRLN-GTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIEC 486
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDV 596
++L G R++L+ L P +AL+ EG ++W D + KIE +DG+ R T++ +
Sbjct: 487 ANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGD-AKTDKIEVINVDGTKRRTLL--ED 543
Query: 597 KWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
K P+ L+ +YW D + +I + + R +I+
Sbjct: 544 KLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVII 582
Score = 95.1 bits (226), Expect = 8e-19
Identities = 47/134 (35%), Positives = 62/134 (46%), Gaps = 5/134 (3%)
Query: 102 EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQM 161
E C P++F C +C+P W CD P+C D SDE+ C C + +F C G+C+ +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGC-PVCSAAQFPCARGQCVDL 1313
Query: 162 RWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCV 221
R E C C P + F C GQC+ CD DC DGSDE+ C
Sbjct: 1314 RLRCDGEADCQDRSDEADCDA-ICLP-NQFRCASGQCVLIKQQCDSFPDCIDGSDELMCE 1371
Query: 222 ST--PKVRSPCIST 233
T P SP S+
Sbjct: 1372 ITKPPSDDSPAHSS 1385
Score = 86.2 bits (204), Expect = 4e-16
Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+CV L
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPV--CSAAQFPCAR--GQCVDLR 1314
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR 162
CD DC D SDE C+ C ++F C +G+C+ ++
Sbjct: 1315 LRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIK 1352
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/291 (23%), Positives = 117/291 (40%), Gaps = 17/291 (5%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C NGGCS C TP C C G +L+ D +TC E + +I +
Sbjct: 601 GTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISL 660
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D + SL + + S++H +V D
Sbjct: 661 ETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEH--VVEFGLD 718
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I A +D G R V++ L LA+D ++
Sbjct: 719 YPEGMAVDWMGKN--LYWADTGTNRIEVARLD-GQFRQVLVWRDLDNPRSLALDPTKGYI 775
Query: 525 YWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMD 584
YWT+ G + + + D++ + ++ + ++WTD IE + M
Sbjct: 776 YWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDL-DTNMIESSNML 834
Query: 585 GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLI 634
G R +++ D+ P GLT +YW D +++I + G R LI
Sbjct: 835 GQER-VVIADDLPHPFGLT--QYSDYIYWTDWNLHSIERADKTSGRNRTLI 882
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/140 (32%), Positives = 56/140 (40%), Gaps = 25/140 (17%)
Query: 183 PTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGC-----VSTPKVRSPCISTEF 235
PTC P F+C G+ CI W CDG +C D SDE GC P R C+
Sbjct: 1257 PTCSPDQ-FACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRL 1315
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C+ C R+ EA C + C +QF+C C+ C+
Sbjct: 1316 RCDGEADCQDRS-------------DEAD--C--DAICLPNQFRCASGQCVLIKQQCDSF 1358
Query: 296 KDCPDGSDEYNCTRQKTICD 315
DC DGSDE C K D
Sbjct: 1359 PDCIDGSDELMCEITKPPSD 1378
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 230 CISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPG 288
C +F C I C+ AW E G C QF C C+
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDE-----EGCPVCSAAQFPCARGQCVDL 1313
Query: 289 ALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
L C+G DC D SDE +C IC +F C G C+ + + CD DC + DE
Sbjct: 1314 RLRCDGEADCQDRSDEADC---DAIC-LPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 38.7 bits (86), Expect = 0.076
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
G N+C NNG C Q C+ P G+ C C Y L +R C
Sbjct: 902 GLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNC 941
>AF064548-1|AAC36467.1| 1615|Homo sapiens low-density lipoprotein
receptor-related protein 5 protein.
Length = 1615
Score = 272 bits (667), Expect = 3e-72
Identities = 134/314 (42%), Positives = 190/314 (60%), Gaps = 15/314 (4%)
Query: 438 PSLLFARKHDIRKISLD--HHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
P LLFA + D+R + E +V+ + A A+D+ F G ++W+DV++E I + +
Sbjct: 33 PLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYL 92
Query: 496 DE---GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRL 552
++ Q V+ G L++ DGLA DWV LYWTD+ N IE+++L G RK+L L
Sbjct: 93 NQTGAAVQNVVISG--LVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDL 150
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVY 612
++PRAIAL+P G+M+WTDWG+ P+IERAGMDGS R IV D+ WPNGLT+DL Q++Y
Sbjct: 151 DQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLY 210
Query: 613 WVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNG 672
W DAK++ I N DGS R+ ++ + L HPF++T D +YWTDW +++ NK G
Sbjct: 211 WADAKLSFIHRANLDGSFRQKVVEGS--LTHPFALTLSGDTLYWTDWQTRSIHACNKRTG 268
Query: 673 KDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCA 732
+ I S L +PM I V RQP C NG CSHLCL P+ P +CA
Sbjct: 269 GKRKEILS--ALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCL----LSPSEPFYTCA 322
Query: 733 CPNGLKLLPDDQMC 746
CP G++L + + C
Sbjct: 323 CPTGVQLQDNGRTC 336
Score = 263 bits (645), Expect = 1e-69
Identities = 143/355 (40%), Positives = 199/355 (56%), Gaps = 20/355 (5%)
Query: 398 DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH 455
D G CS +C+ + C C TG RT CKA LL AR+ D+R+ISLD
Sbjct: 302 DNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRT-CKAG-AEEVLLLARRTDLRRISLDT 359
Query: 456 HEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
+ IV +D + A A+DY G ++W+D I +A +D G+ ++ ++
Sbjct: 360 PDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLD-GSGAQTLVNTEINDP 418
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
DG+AVDWV +LYWTDTG + IE++ L G RKIL+ + L+EPRAIAL+P+ G M+WTDW
Sbjct: 419 DGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDW 478
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G+ PKIE A +DG R +V+ + WPNGL LDL ++YW DAK + I N DG+ RR
Sbjct: 479 GENPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRR 538
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+L + L H F T D++YWTDW + ++ R +K I L ++V
Sbjct: 539 TLLE--DKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNV 596
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+ G N CA NG CSHLC F P++ R C CP GL+LL D + C+
Sbjct: 597 ----AKVVGTNPCADRNGGCSHLCF----FTPHATR--CGCPIGLELLSDMKTCI 641
Score = 217 bits (530), Expect = 1e-55
Identities = 133/369 (36%), Positives = 199/369 (53%), Gaps = 20/369 (5%)
Query: 381 GYKLIDNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS 439
G K ++ + CAD G CS +C +C C G D C E
Sbjct: 590 GLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLEL-LSDMKTCIVPEAF-- 646
Query: 440 LLFARKHDIRKISLD-HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
L+F + I +ISL+ ++ VAI + K A+ALD+ I+W+DV+ + I +A ++
Sbjct: 647 LVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMN- 705
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
G+ V+ L +G+AVDW+ +LYW DTG N IE++ L G R++L+ L+ PR+
Sbjct: 706 GSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRS 765
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
+AL+P +G+++WT+WG P+I RA MDG++ T+V V N LT+D QR+YW D
Sbjct: 766 LALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVD-KVGRANDLTIDYADQRLYWTDLD 824
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
N I S N G R +I + L HPF +T + D++YWTDW+ ++ RA+K +G++
Sbjct: 825 TNMIESSNMLGQERVVI---ADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRN-RT 880
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ H L M I V+H RQ DG+N C NG C LCL P G + C C +
Sbjct: 881 LIQGH-LDFVMDILVFHSSRQ-DGLNDCMHNNGQCGQLCLAIP--GGH----RCGCASHY 932
Query: 738 KLLPDDQMC 746
L P + C
Sbjct: 933 TLDPSSRNC 941
Score = 142 bits (343), Expect = 6e-33
Identities = 107/369 (28%), Positives = 174/369 (47%), Gaps = 25/369 (6%)
Query: 391 EDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI- 448
+ +++C + G C Q+C+ G +C C + Y DP R T LLF++K I
Sbjct: 901 DGLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTT---FLLFSQKSAIS 957
Query: 449 RKISLDHH--EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG 506
R I D H +++ ++ ++ A+DY I+W D + I +A D+GTQ V+
Sbjct: 958 RMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVD-GRQNIKRAK-DDGTQPFVLTS 1015
Query: 507 -EQLITSD----GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALN 561
Q D L++D L+WT N I + L G +++R ++PRAI +N
Sbjct: 1016 LSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVN 1075
Query: 562 PLEGWMFWTDW-GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT 620
G++++T+ + KIERA +DG+ R + + + P L +D +++WVDA +
Sbjct: 1076 AERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKR 1135
Query: 621 ISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITS 680
I SC+ G+ RL L +++ P +T +YW D + + R K G I
Sbjct: 1136 IESCDLSGA-NRLTLEDANIVQ-PLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQG 1193
Query: 681 THTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKL 739
+ + IH + H CA NG CSH+C+ G +PR C+CP L L
Sbjct: 1194 --RVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAK---GDGTPR--CSCPVHLVL 1246
Query: 740 LPDDQMCVE 748
L + C E
Sbjct: 1247 LQNLLTCGE 1255
Score = 106 bits (254), Expect = 3e-22
Identities = 55/129 (42%), Positives = 68/129 (52%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP +W+CD +C D SDE+ C VC +F C +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEG--CP----VCSAAQFPC-AR 1307
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G C+ RCD ADC D SDE C+ C P +F C G+CV + CD PDC DG
Sbjct: 1308 GQCVDLRLRCDGEADCQDRSDEADCDA-ICLPNQFRCAS--GQCVLIKQQCDSFPDCIDG 1364
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1365 SDELMCEIT 1373
Score = 100 bits (239), Expect = 2e-20
Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 24/339 (7%)
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
TR C+KRT GG + +D E R CE++NGGCS C
Sbjct: 257 TRSIHACNKRT-----GGKRKEILSALYSPMDIQVLSQE-RQPFFHTRCEEDNGGCSHLC 310
Query: 368 VDTPIG--YYCDCEKGYKLIDN-RTC----EDIDECADPGSCSQICINEKGTFKCECHTG 420
+ +P Y C C G +L DN RTC E++ A +I ++
Sbjct: 311 LLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVD 370
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN---DTKSATALDYVFRT 477
R EG+ IR+ LD +VN + A+D+V R
Sbjct: 371 DIRH-AIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARN 429
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIEL 536
++W+D ++I ++ GT R +++ E L +A+ V +YWTD G N IE
Sbjct: 430 --LYWTDTGTDRIEVTRLN-GTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIEC 486
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDV 596
++L G R++L+ L P +AL+ EG ++W D + KIE +DG+ R T++ +
Sbjct: 487 ANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGD-AKTDKIEVINVDGTKRRTLL--ED 543
Query: 597 KWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
K P+ L+ +YW D + +I + + R +I+
Sbjct: 544 KLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVII 582
Score = 95.1 bits (226), Expect = 8e-19
Identities = 47/134 (35%), Positives = 62/134 (46%), Gaps = 5/134 (3%)
Query: 102 EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQM 161
E C P++F C +C+P W CD P+C D SDE+ C C + +F C G+C+ +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGC-PVCSAAQFPCARGQCVDL 1313
Query: 162 RWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCV 221
R E C C P + F C GQC+ CD DC DGSDE+ C
Sbjct: 1314 RLRCDGEADCQDRSDEADCDA-ICLP-NQFRCASGQCVLIKQQCDSFPDCIDGSDELMCE 1371
Query: 222 ST--PKVRSPCIST 233
T P SP S+
Sbjct: 1372 ITKPPSDDSPAHSS 1385
Score = 86.2 bits (204), Expect = 4e-16
Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+CV L
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPV--CSAAQFPCAR--GQCVDLR 1314
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR 162
CD DC D SDE C+ C ++F C +G+C+ ++
Sbjct: 1315 LRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIK 1352
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/291 (23%), Positives = 117/291 (40%), Gaps = 17/291 (5%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C NGGCS C TP C C G +L+ D +TC E + +I +
Sbjct: 601 GTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISL 660
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D + SL + + S++H +V D
Sbjct: 661 ETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEH--VVEFGLD 718
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I A +D G R V++ L LA+D ++
Sbjct: 719 YPEGMAVDWMGKN--LYWADTGTNRIEVARLD-GQFRQVLVWRDLDNPRSLALDPTKGYI 775
Query: 525 YWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMD 584
YWT+ G + + + D++ + ++ + ++WTD IE + M
Sbjct: 776 YWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDL-DTNMIESSNML 834
Query: 585 GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLI 634
G R +++ D+ P GLT +YW D +++I + G R LI
Sbjct: 835 GQER-VVIADDLPHPFGLT--QYSDYIYWTDWNLHSIERADKTSGRNRTLI 882
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/140 (32%), Positives = 56/140 (40%), Gaps = 25/140 (17%)
Query: 183 PTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGC-----VSTPKVRSPCISTEF 235
PTC P F+C G+ CI W CDG +C D SDE GC P R C+
Sbjct: 1257 PTCSPDQ-FACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRL 1315
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C+ C R+ EA C + C +QF+C C+ C+
Sbjct: 1316 RCDGEADCQDRS-------------DEAD--C--DAICLPNQFRCASGQCVLIKQQCDSF 1358
Query: 296 KDCPDGSDEYNCTRQKTICD 315
DC DGSDE C K D
Sbjct: 1359 PDCIDGSDELMCEITKPPSD 1378
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 230 CISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPG 288
C +F C I C+ AW E G C QF C C+
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDE-----EGCPVCSAAQFPCARGQCVDL 1313
Query: 289 ALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
L C+G DC D SDE +C IC +F C G C+ + + CD DC + DE
Sbjct: 1314 RLRCDGEADCQDRSDEADC---DAIC-LPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 38.7 bits (86), Expect = 0.076
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
G N+C NNG C Q C+ P G+ C C Y L +R C
Sbjct: 902 GLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNC 941
>AB209683-1|BAD92920.1| 1477|Homo sapiens low density lipoprotein
receptor-related protein 6 variant protein.
Length = 1477
Score = 272 bits (667), Expect = 3e-72
Identities = 149/357 (41%), Positives = 207/357 (57%), Gaps = 24/357 (6%)
Query: 398 DPGSCSQICINE--KGTFKCECHTGYARDPRDRTRCK--ATEGHPSLLFARKHDIRKISL 453
D G CS +C+ K ++C C TG +T CK ATE LL AR+ D+R+ISL
Sbjct: 153 DNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKT-CKDGATE---LLLLARRTDLRRISL 208
Query: 454 DHHEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLI 510
D + IV D + A A+DY G I+W+D I ++ ID G+ V+ Q+
Sbjct: 209 DTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFID-GSGSQFVVTAQIA 267
Query: 511 TSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWT 570
DG+AVDWV +LYWTDTG + IE++ L G MRKILI + LEEPRAI L+P+ G+M+WT
Sbjct: 268 HPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWT 327
Query: 571 DWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSG 630
DWG++PKIERA +DGS R +V+ + WPNGL LD ++YW DAK + I N DG+G
Sbjct: 328 DWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTG 387
Query: 631 RRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVI 690
RR+++ + + H F T D+VYWTDW + ++ R +K + + I L
Sbjct: 388 RRVLVE--DKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKAT 445
Query: 691 HVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+V+ G N CA NG CSHLCL P+ + CACP G +L+ D + C+
Sbjct: 446 NVHRVI----GSNPCAEENGGCSHLCLYRPQ------GLRCACPIGFELISDMKTCI 492
Score = 264 bits (647), Expect = 8e-70
Identities = 146/354 (41%), Positives = 209/354 (59%), Gaps = 19/354 (5%)
Query: 396 CADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLD 454
CA+ G CS +C+ +C C G+ D C E LLF+R+ DIR+ISL+
Sbjct: 456 CAEENGGCSHLCLYRPQGLRCACPIGFELIS-DMKTCIVPEAF--LLFSRRADIRRISLE 512
Query: 455 -HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
++ VAI + K A+ALD+ I+W+D++ + I +A ++ G+ V+ L
Sbjct: 513 TNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMN-GSALEHVVEFGLDYP 571
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
+G+AVDW+ +LYW DTG N IE+S L G R++L+ L+ PRA+AL+P EG+M+WT+W
Sbjct: 572 EGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEW 631
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G PKI+RA MDGS R+T+V +V NGLT+D ++R+YW D N I S N G R
Sbjct: 632 GGKPKIDRAAMDGSERTTLVP-NVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNRE 690
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+I + L HPF +T ++D++YWTDW + ++ RANK +G++ I H L M I V
Sbjct: 691 VI---ADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQN-RTIIQGH-LDYVMDILV 745
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+H RQ G N CA+ NGHCSHLCL P G C CP L D++ C
Sbjct: 746 FHSSRQ-SGWNECASSNGHCSHLCLAVPVGG-----FVCGCPAHYSLNADNRTC 793
Score = 212 bits (517), Expect = 5e-54
Identities = 95/195 (48%), Positives = 128/195 (65%), Gaps = 8/195 (4%)
Query: 552 LEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRV 611
L++PRAIAL+P G+M+WTDWG+VPKIERAGMDGS R I++ ++ WPNGLTLD Q++
Sbjct: 1 LDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDYEEQKL 60
Query: 612 YWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFN 671
YW DAK+N I N DG+ R+ ++ + L HPF++T FED +YWTDW ++ NK+
Sbjct: 61 YWADAKLNFIHKSNLDGTNRQAVVKGS--LPHPFALTLFEDILYWTDWSTHSILACNKYT 118
Query: 672 GKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSC 731
G+ + I S + +PM IH + RQP+ N C NG CSHLCL P P C
Sbjct: 119 GEGLREIHS--DIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCL----MSPVKPFYQC 172
Query: 732 ACPNGLKLLPDDQMC 746
ACP G+KLL + + C
Sbjct: 173 ACPTGVKLLENGKTC 187
Score = 157 bits (382), Expect = 1e-37
Identities = 107/366 (29%), Positives = 179/366 (48%), Gaps = 22/366 (6%)
Query: 394 DECADP-GSCSQICINEK-GTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKI 451
+ECA G CS +C+ G F C C Y+ + +RT C A LLF++K I ++
Sbjct: 755 NECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRT-CSAPTTF--LLFSQKSAINRM 811
Query: 452 SLDHHE---MVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG-- 506
+D + ++ ++ ++ A+DY ++W D I KA D TVV+
Sbjct: 812 VIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 871
Query: 507 --EQL-ITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPL 563
+ L I L++D ++YWT N I ++ L G ++++ + PRAI +NP
Sbjct: 872 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAIVVNPE 931
Query: 564 EGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTIS 622
+G+M++T+ + PKIERA +DG+ R + + P L LD +++W D+ + I
Sbjct: 932 KGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIE 991
Query: 623 SCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTH 682
S + G+ R++L + +L+ P +T FE+W+YW D + + + + G++
Sbjct: 992 SSDLSGA-NRIVLEDSNILQ-PVGLTVFENWLYWIDKQQQMIEKID-MTGREGRTKVQAR 1048
Query: 683 TLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPD 742
Q + V Q + CA NG CSH+CL G + R C+CP L LL D
Sbjct: 1049 IAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVK---GDGTTR--CSCPMHLVLLQD 1103
Query: 743 DQMCVE 748
+ C E
Sbjct: 1104 ELSCGE 1109
Score = 103 bits (247), Expect = 2e-21
Identities = 56/129 (43%), Positives = 71/129 (55%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP++W+CD +C D SDE C VC E +F+C S
Sbjct: 1109 EPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDE--LNCP----VCSESQFQCAS- 1161
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G CI + RC+ A+C D SDE CEV C ++F C G+C+ CD N DCSD
Sbjct: 1162 GQCIDGALRCNGDANCQDKSDEKNCEV-LCLIDQFRCAN--GQCIGKHKKCDHNVDCSDK 1218
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1219 SDELDCYPT 1227
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/167 (32%), Positives = 72/167 (43%), Gaps = 13/167 (7%)
Query: 67 QEYR-FECLSDG-----LCIPR---SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGK 116
QEYR C D +C+ + + RC DE C E C P++FTC
Sbjct: 1064 QEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTG 1123
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
+C+P+ W CD +C D SDE C C +F C +G+CI
Sbjct: 1124 EIDCIPVAWRCDGFTECEDHSDELNC-PVCSESQFQCASGQCIDGALRCNGDANCQDKSD 1182
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVST 223
E C Q F C +GQCI CD +VDC+D SDE+ C T
Sbjct: 1183 EKNCEVLCLIDQ--FRCANGQCIGKHKKCDHNVDCSDKSDELDCYPT 1227
Score = 87.8 bits (208), Expect = 1e-16
Identities = 46/135 (34%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+C+
Sbjct: 1113 CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPV--CSESQFQCAS--GQCIDGA 1168
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT 184
C+ + +C D SDEK C C D+F C NG+CI E+ C PT
Sbjct: 1169 LRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDELDC-YPT 1227
Query: 185 CQPQSHFSCTDGQCI 199
+P + T G I
Sbjct: 1228 EEPAPQATNTVGSVI 1242
Score = 75.8 bits (178), Expect = 5e-13
Identities = 72/292 (24%), Positives = 125/292 (42%), Gaps = 18/292 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C + NGGCS C+ P G C C G++LI D +TC E + +I +
Sbjct: 452 GSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISL 511
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D T + SL + + +L+H +V D
Sbjct: 512 ETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEH--VVEFGLD 569
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I + +D G R V++ + L + LA+D +
Sbjct: 570 YPEGMAVDWLGKN--LYWADTGTNRIEVSKLD-GQHRQVLVWKDLDSPRALALDPAEGFM 626
Query: 525 YWTDTGHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGM 583
YWT+ G I+ + + G+ R L+ + + ++ + ++WTD IE + M
Sbjct: 627 YWTEWGGKPKIDRAAMDGSERTTLV-PNVGRANGLTIDYAKRRLYWTDL-DTNLIESSNM 684
Query: 584 DGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
G +R +++ D+ P GLT + +YW D +I N R I+
Sbjct: 685 LGLNRE-VIADDLPHPFGLT--QYQDYIYWTDWSRRSIERANKTSGQNRTII 733
Score = 72.1 bits (169), Expect = 7e-12
Identities = 71/291 (24%), Positives = 125/291 (42%), Gaps = 19/291 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPI-GYYCDCEKGYKL-IDNRTCEDIDE---CADPGSCSQIC 406
G NEC +NG CS C+ P+ G+ C C Y L DNRTC + + +++
Sbjct: 753 GWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMV 812
Query: 407 INEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHE-MVAIVNDT 465
I+E+ + R+ R + + +R++ IRK D + +V+
Sbjct: 813 IDEQQSPDIILPIHSLRNVR-AIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSV 871
Query: 466 KSATA------LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
S L + I+W+ I +D + V+ GEQ + V+
Sbjct: 872 PSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAIVVNP 930
Query: 520 VYNHLYWTDTGHN--HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPK 577
++Y+T+ IE + L G R++L L +P A+AL+ G +FW D + +
Sbjct: 931 EKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWAD-SDLRR 989
Query: 578 IERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
IE + + G++R + ++ P GLT + +YW+D + I + G
Sbjct: 990 IESSDLSGANRIVLEDSNILQPVGLT--VFENWLYWIDKQQQMIEKIDMTG 1038
Score = 71.7 bits (168), Expect = 9e-12
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 216 DEVGCVSTPKVRSPCISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR 274
DE+ C P C +F C I C+ AW E C C
Sbjct: 1103 DELSCGEPPT----CSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELN--CP---VCS 1153
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
QFQC CI GAL CNG +C D SDE NC + +C +F C G CI K C
Sbjct: 1154 ESQFQCASGQCIDGALRCNGDANCQDKSDEKNC---EVLC-LIDQFRCANGQCIGKHKKC 1209
Query: 335 DKHVDCPNFEDE 346
D +VDC + DE
Sbjct: 1210 DHNVDCSDKSDE 1221
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 177 EVKC-PTPTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCIST 233
E+ C PTC PQ F+C G+ CI W CDG +C D SDE+ C C +
Sbjct: 1104 ELSCGEPPTCSPQQ-FTCFTGEIDCIPVAWRCDGFTECEDHSDELNC-------PVCSES 1155
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCN 293
+F+C C+ A E + C V C +DQF+C + CI C+
Sbjct: 1156 QFQCASG-QCIDGALRCNGDANCQDKSDE--KNCE--VLCLIDQFRCANGQCIGKHKKCD 1210
Query: 294 GVKDCPDGSDEYNC 307
DC D SDE +C
Sbjct: 1211 HNVDCSDKSDELDC 1224
Score = 66.9 bits (156), Expect = 3e-10
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 464 DTKSATALDYVFRTGMIFWSDVND-EKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYN 522
D A ALD +G ++W+D + KI +A +D G+ R ++I ++ +GL +D+
Sbjct: 2 DQPRAIALDP--SSGFMYWTDWGEVPKIERAGMD-GSSRFIIINSEIYWPNGLTLDYEEQ 58
Query: 523 HLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
LYW D N I S+L G R+ +++ L P A+ L E ++WTDW
Sbjct: 59 KLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTL--FEDILYWTDW 106
Score = 43.6 bits (98), Expect = 0.003
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIG--YYCDCEKGYKLIDN-RTCED 392
N C +NGGCS C+ +P+ Y C C G KL++N +TC+D
Sbjct: 148 NPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKD 189
>AB017498-1|BAA33051.1| 1615|Homo sapiens Lipoprotein Receptor
Related Protein 5 protein.
Length = 1615
Score = 272 bits (667), Expect = 3e-72
Identities = 134/314 (42%), Positives = 190/314 (60%), Gaps = 15/314 (4%)
Query: 438 PSLLFARKHDIRKISLD--HHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPI 495
P LLFA + D+R + E +V+ + A A+D+ F G ++W+DV++E I + +
Sbjct: 33 PLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYL 92
Query: 496 DE---GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRL 552
++ Q V+ G L++ DGLA DWV LYWTD+ N IE+++L G RK+L L
Sbjct: 93 NQTGAAVQNVVISG--LVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDL 150
Query: 553 EEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVY 612
++PRAIAL+P G+M+WTDWG+ P+IERAGMDGS R IV D+ WPNGLT+DL Q++Y
Sbjct: 151 DQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLY 210
Query: 613 WVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNG 672
W DAK++ I N DGS R+ ++ + L HPF++T D +YWTDW +++ NK G
Sbjct: 211 WADAKLSFIHRANLDGSFRQKVVEGS--LTHPFALTLSGDTLYWTDWQTRSIHACNKRTG 268
Query: 673 KDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCA 732
+ I S L +PM I V RQP C NG CSHLCL P+ P +CA
Sbjct: 269 GKRKEILS--ALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCL----LSPSEPFYTCA 322
Query: 733 CPNGLKLLPDDQMC 746
CP G++L + + C
Sbjct: 323 CPTGVQLQDNGRTC 336
Score = 263 bits (645), Expect = 1e-69
Identities = 143/355 (40%), Positives = 199/355 (56%), Gaps = 20/355 (5%)
Query: 398 DPGSCSQICINEKGT--FKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH 455
D G CS +C+ + C C TG RT CKA LL AR+ D+R+ISLD
Sbjct: 302 DNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRT-CKAG-AEEVLLLARRTDLRRISLDT 359
Query: 456 HEMVAIV---NDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITS 512
+ IV +D + A A+DY G ++W+D I +A +D G+ ++ ++
Sbjct: 360 PDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLD-GSGAQTLVNTEINDP 418
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
DG+AVDWV +LYWTDTG + IE++ L G RKIL+ + L+EPRAIAL+P+ G M+WTDW
Sbjct: 419 DGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDW 478
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
G+ PKIE A +DG R +V+ + WPNGL LDL ++YW DAK + I N DG+ RR
Sbjct: 479 GENPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRR 538
Query: 633 LILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHV 692
+L + L H F T D++YWTDW + ++ R +K I L ++V
Sbjct: 539 TLLE--DKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNV 596
Query: 693 YHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
+ G N CA NG CSHLC F P++ R C CP GL+LL D + C+
Sbjct: 597 ----AKVVGTNPCADRNGGCSHLCF----FTPHATR--CGCPIGLELLSDMKTCI 641
Score = 217 bits (530), Expect = 1e-55
Identities = 133/369 (36%), Positives = 199/369 (53%), Gaps = 20/369 (5%)
Query: 381 GYKLIDNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPS 439
G K ++ + CAD G CS +C +C C G D C E
Sbjct: 590 GLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLEL-LSDMKTCIVPEAF-- 646
Query: 440 LLFARKHDIRKISLD-HHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
L+F + I +ISL+ ++ VAI + K A+ALD+ I+W+DV+ + I +A ++
Sbjct: 647 LVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMN- 705
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
G+ V+ L +G+AVDW+ +LYW DTG N IE++ L G R++L+ L+ PR+
Sbjct: 706 GSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRS 765
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAK 617
+AL+P +G+++WT+WG P+I RA MDG++ T+V V N LT+D QR+YW D
Sbjct: 766 LALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVD-KVGRANDLTIDYADQRLYWTDLD 824
Query: 618 MNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEA 677
N I S N G R +I + L HPF +T + D++YWTDW+ ++ RA+K +G++
Sbjct: 825 TNMIESSNMLGQERVVI---ADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRN-RT 880
Query: 678 ITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGL 737
+ H L M I V+H RQ DG+N C NG C LCL P G + C C +
Sbjct: 881 LIQGH-LDFVMDILVFHSSRQ-DGLNDCMHNNGQCGQLCLAIP--GGH----RCGCASHY 932
Query: 738 KLLPDDQMC 746
L P + C
Sbjct: 933 TLDPSSRNC 941
Score = 142 bits (343), Expect = 6e-33
Identities = 107/369 (28%), Positives = 174/369 (47%), Gaps = 25/369 (6%)
Query: 391 EDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDI- 448
+ +++C + G C Q+C+ G +C C + Y DP R T LLF++K I
Sbjct: 901 DGLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTT---FLLFSQKSAIS 957
Query: 449 RKISLDHH--EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIG 506
R I D H +++ ++ ++ A+DY I+W D + I +A D+GTQ V+
Sbjct: 958 RMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVD-GRQNIKRAK-DDGTQPFVLTS 1015
Query: 507 -EQLITSD----GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALN 561
Q D L++D L+WT N I + L G +++R ++PRAI +N
Sbjct: 1016 LSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVN 1075
Query: 562 PLEGWMFWTDW-GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT 620
G++++T+ + KIERA +DG+ R + + + P L +D +++WVDA +
Sbjct: 1076 AERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKR 1135
Query: 621 ISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITS 680
I SC+ G+ RL L +++ P +T +YW D + + R K G I
Sbjct: 1136 IESCDLSGA-NRLTLEDANIVQ-PLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQG 1193
Query: 681 THTLQNPMVIHVYHPYRQPDGVNH-CAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKL 739
+ + IH + H CA NG CSH+C+ G +PR C+CP L L
Sbjct: 1194 --RVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAK---GDGTPR--CSCPVHLVL 1246
Query: 740 LPDDQMCVE 748
L + C E
Sbjct: 1247 LQNLLTCGE 1255
Score = 105 bits (253), Expect = 4e-22
Identities = 55/129 (42%), Positives = 68/129 (52%), Gaps = 12/129 (9%)
Query: 19 ESRTCTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
E TC+ +F C TG CIP +W+CD +C D SDE+ C VC +F C +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEG--CP----VCSAAQFPC-AR 1307
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
G C+ RCD ADC D SDE C+ C P +F C G+CV + CD PDC DG
Sbjct: 1308 GQCVDLRLRCDGEADCQDRSDEVDCDA-ICLPNQFRCAS--GQCVLIKQQCDSFPDCIDG 1364
Query: 137 SDEKACNET 145
SDE C T
Sbjct: 1365 SDELMCEIT 1373
Score = 100 bits (239), Expect = 2e-20
Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 24/339 (7%)
Query: 308 TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRC 367
TR C+KRT GG + +D E R CE++NGGCS C
Sbjct: 257 TRSIHACNKRT-----GGKRKEILSALYSPMDIQVLSQE-RQPFFHTRCEEDNGGCSHLC 310
Query: 368 VDTPIG--YYCDCEKGYKLIDN-RTC----EDIDECADPGSCSQICINEKGTFKCECHTG 420
+ +P Y C C G +L DN RTC E++ A +I ++
Sbjct: 311 LLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVD 370
Query: 421 YARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVN---DTKSATALDYVFRT 477
R EG+ IR+ LD +VN + A+D+V R
Sbjct: 371 DIRH-AIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARN 429
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN-HIEL 536
++W+D ++I ++ GT R +++ E L +A+ V +YWTD G N IE
Sbjct: 430 --LYWTDTGTDRIEVTRLN-GTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIEC 486
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDV 596
++L G R++L+ L P +AL+ EG ++W D + KIE +DG+ R T++ +
Sbjct: 487 ANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGD-AKTDKIEVINVDGTKRRTLL--ED 543
Query: 597 KWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLIL 635
K P+ L+ +YW D + +I + + R +I+
Sbjct: 544 KLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVII 582
Score = 96.7 bits (230), Expect = 3e-19
Identities = 48/134 (35%), Positives = 63/134 (47%), Gaps = 5/134 (3%)
Query: 102 EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQM 161
E C P++F C +C+P W CD P+C D SDE+ C C + +F C G+C+ +
Sbjct: 1255 EPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGC-PVCSAAQFPCARGQCVDL 1313
Query: 162 RWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCV 221
R EV C C P + F C GQC+ CD DC DGSDE+ C
Sbjct: 1314 RLRCDGEADCQDRSDEVDCDA-ICLP-NQFRCASGQCVLIKQQCDSFPDCIDGSDELMCE 1371
Query: 222 ST--PKVRSPCIST 233
T P SP S+
Sbjct: 1372 ITKPPSDDSPAHSS 1385
Score = 85.8 bits (203), Expect = 5e-16
Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
Query: 66 CQEYRFECLSDGL-CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLT 124
C +F C + + CIP +WRCD +C D SDE C V C +F C G+CV L
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPV--CSAAQFPCAR--GQCVDLR 1314
Query: 125 WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR 162
CD DC D SDE C+ C ++F C +G+C+ ++
Sbjct: 1315 LRCDGEADCQDRSDEVDCDAICLPNQFRCASGQCVLIK 1352
Score = 68.1 bits (159), Expect = 1e-10
Identities = 69/291 (23%), Positives = 117/291 (40%), Gaps = 17/291 (5%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTC---EDIDECADPGSCSQICI 407
G N C NGGCS C TP C C G +L+ D +TC E + +I +
Sbjct: 601 GTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISL 660
Query: 408 NEKGTFKCECHTGYARDPR---DRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVND 464
TG D + SL + + S++H +V D
Sbjct: 661 ETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEH--VVEFGLD 718
Query: 465 TKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHL 524
A+D++ + ++W+D +I A +D G R V++ L LA+D ++
Sbjct: 719 YPEGMAVDWMGKN--LYWADTGTNRIEVARLD-GQFRQVLVWRDLDNPRSLALDPTKGYI 775
Query: 525 YWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMD 584
YWT+ G + + + D++ + ++ + ++WTD IE + M
Sbjct: 776 YWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDL-DTNMIESSNML 834
Query: 585 GSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN-YDGSGRRLI 634
G R +++ D+ P GLT +YW D +++I + G R LI
Sbjct: 835 GQER-VVIADDLPHPFGLT--QYSDYIYWTDWNLHSIERADKTSGRNRTLI 882
Score = 64.9 bits (151), Expect = 1e-09
Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 25/140 (17%)
Query: 183 PTCQPQSHFSCTDGQ--CISAWWHCDGDVDCADGSDEVGC-----VSTPKVRSPCISTEF 235
PTC P F+C G+ CI W CDG +C D SDE GC P R C+
Sbjct: 1257 PTCSPDQ-FACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRL 1315
Query: 236 ECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGV 295
C+ C R+ + ++ C + C +QF+C C+ C+
Sbjct: 1316 RCDGEADCQDRS--------------DEVD-C--DAICLPNQFRCASGQCVLIKQQCDSF 1358
Query: 296 KDCPDGSDEYNCTRQKTICD 315
DC DGSDE C K D
Sbjct: 1359 PDCIDGSDELMCEITKPPSD 1378
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 230 CISTEFEC-NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPG 288
C +F C I C+ AW E G C QF C C+
Sbjct: 1259 CSPDQFACATGEIDCIPGAWRCDGFPECDDQSDE-----EGCPVCSAAQFPCARGQCVDL 1313
Query: 289 ALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
L C+G DC D SDE +C IC +F C G C+ + + CD DC + DE
Sbjct: 1314 RLRCDGEADCQDRSDEVDC---DAIC-LPNQFRCASGQCVLIKQQCDSFPDCIDGSDE 1367
Score = 38.7 bits (86), Expect = 0.076
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
G N+C NNG C Q C+ P G+ C C Y L +R C
Sbjct: 902 GLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNC 941
>AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppressor
protein protein.
Length = 881
Score = 259 bits (634), Expect = 3e-68
Identities = 168/519 (32%), Positives = 256/519 (49%), Gaps = 38/519 (7%)
Query: 268 RGNVTCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDC-G 323
R C +F C DH +C+ + C+G DCPD SDE C + I C G
Sbjct: 27 RDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLG 86
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGE--NECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C+ LS++C+ +DCP+ DE C E + C++ N C +C C CE G
Sbjct: 87 TNKCVHLSQLCNGVLDCPDGYDEGV-HCQELLSNCQQLN--CQYKCTMVRNSTRCYCEDG 143
Query: 382 YKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEG 436
+++ D R+C+D DECA G+CSQ C N G++ C C GY P +R+ CKA T+
Sbjct: 144 FEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRS-CKAKIEPTDR 202
Query: 437 HPSLLFARKHDIRKISLDHHEMVAI--VNDTKSATALDYVFRTGMIFWSDV----NDEKI 490
P LL A I L+ +M + VN + T LD+++ MI W + N K
Sbjct: 203 PPILLIANFETIEVFYLNGSKMATLSSVNGNEIHT-LDFIYNEDMICWIESRESSNQLKC 261
Query: 491 YKAPIDEGT--QRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILI 548
+ G + T+ I + +A+DW+ +LY+ D + I + + G++ LI
Sbjct: 262 IQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFVDHVGDRIFVCNSNGSVCVTLI 321
Query: 549 RDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
L P+AIA++P+ G +F+TD+G V K+ER MDG +R+ I+ + P L LDLV
Sbjct: 322 DLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALALDLVN 381
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+ VYWVD ++ + +Y G R ++ +V RH + IT FED++Y T+ D + R N
Sbjct: 382 KLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQV-RHLYGITVFEDYLYATNSDNYNIVRIN 440
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRFG 723
+FNG D+ ++ ++N I +Y QP +H V+ G CSH+CL + +
Sbjct: 441 RFNGTDIHSLIK---IENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYK 497
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHFLPFYNNFR 762
+C C G L D + FL FY R
Sbjct: 498 TR----TCRCRTGFNLGSDGRSYKRPKNELFL-FYGKGR 531
Score = 188 bits (458), Expect = 6e-47
Identities = 124/381 (32%), Positives = 188/381 (49%), Gaps = 36/381 (9%)
Query: 385 IDNRTCEDIDECADPGSCSQICINEKG--TFKCECHTGY--ARDPRDRTRCKAT------ 434
+ + CE +D PG CS IC+ T C C TG+ D R R K
Sbjct: 470 VRSHACE-VDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRSYKRPKNELFLFYG 528
Query: 435 EGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAP 494
+G P ++ R D+ D + M+ I N + ALD+ T I+++D I +
Sbjct: 529 KGRPGIV--RGMDLNTKIADEY-MIPIEN-LVNPRALDFHAETNYIYFADTTSFLIGRQK 584
Query: 495 IDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDR 551
ID GT+R ++ + L +G+AVDW+ N+LYWT+ GH I ++ L+ RK L+
Sbjct: 585 ID-GTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGE 643
Query: 552 LEEPRAIALNPLEGWMFWTDWGQ------VPKIERAGMDGSHRSTIVSYDVKWPNGLTLD 605
+ PR I ++P+ GWM+WTDW + V +IE+A MDG +R V+ + WPNGLTLD
Sbjct: 644 MSHPRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLD 703
Query: 606 LVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVY 665
+YW DA + I +G+ R+ I++S L HPF ++ ++V+WTD+ +++
Sbjct: 704 FHTNTLYWCDAYYDHIEKVFLNGTHRK-IVYSGRELNHPFGLSHHGNYVFWTDYMNGSIF 762
Query: 666 RANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPN 725
+ + E H + +Y P R+ G N C NG CS LCL P
Sbjct: 763 QLDLITS---EVTLLRHERPPLFGLQIYDP-RKQQGDNMCRVNNGGCSTLCLAIP----- 813
Query: 726 SPRVSCACPNGLKLLPDDQMC 746
RV CAC + L + C
Sbjct: 814 GGRV-CACADNQLLDENGTTC 833
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/168 (30%), Positives = 78/168 (46%), Gaps = 11/168 (6%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELC--RGNVTCRLDQFQC-KDHSCI 286
C EF C+D +TCV ++W+ E+L+ C + C L+ C + C+
Sbjct: 32 CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCV 91
Query: 287 PGALYCNGVKDCPDGSDE-YNCTRQKTICDK-RTEFDCGGGMCIPLSKVCDKHVDCPNFE 344
+ CNGV DCPDG DE +C + C + ++ C + S C D
Sbjct: 92 HLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKC---TMVRNSTRCYCE-DGFEIT 147
Query: 345 DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCE 391
++ R ++EC G CSQ C +T Y C C +GY + DNR+C+
Sbjct: 148 EDGRSCKDQDECAV-YGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCK 194
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/152 (29%), Positives = 63/152 (41%), Gaps = 18/152 (11%)
Query: 19 ESRTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVC-TATKMVCQEYRFECLSD 76
+ + C EF C C+ SW CD + DC D SDE C ++ C CL
Sbjct: 28 DQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGT 87
Query: 77 GLCIPRSWRCDATADCPDGSDEH-QCEVEACGPEEFTCRGK--------PGECVPLTWMC 127
C+ S C+ DCPDG DE C+ ++ C+ K C +
Sbjct: 88 NKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEIT 147
Query: 128 DDNPDCSDGSDEKA----CNETCRS--DEFTC 153
+D C D DE A C++TCR+ +TC
Sbjct: 148 EDGRSCKD-QDECAVYGTCSQTCRNTHGSYTC 178
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/106 (34%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
Query: 63 KMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE--HQC--EVE-ACGPEEFTCRGKP 117
+ +C F C C+ +SW CD DCPD SDE C EVE C C G
Sbjct: 29 QQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLG-T 87
Query: 118 GECVPLTWMCDDNPDCSDGSDEKA-CNETCRSDEFTCGNGKCIQMR 162
+CV L+ +C+ DC DG DE C E + + KC +R
Sbjct: 88 NKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVR 133
Score = 54.0 bits (124), Expect = 2e-06
Identities = 20/37 (54%), Positives = 22/37 (59%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVC 59
C + EFRCK CI WKCD + DC D SDED C
Sbjct: 845 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNC 881
Score = 45.6 bits (103), Expect = 7e-04
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 346 EPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPG-SCS 403
+PR + G+N C NNGGCS C+ P G C C L +N T C +PG +
Sbjct: 788 DPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGT-----TCTFNPGEALP 842
Query: 404 QICINEKGTFKCE 416
IC + G F+C+
Sbjct: 843 HIC--KAGEFRCK 853
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/62 (38%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 185 CQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C P F C D C+S W CDGD DC D SDE +V C C C
Sbjct: 32 CDP-GEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKC 90
Query: 244 VH 245
VH
Sbjct: 91 VH 92
Score = 44.8 bits (101), Expect = 0.001
Identities = 17/27 (62%), Positives = 18/27 (66%)
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDE 217
F C + CI A W CDGD DC DGSDE
Sbjct: 850 FRCKNRHCIQARWKCDGDDDCLDGSDE 876
Score = 43.2 bits (97), Expect = 0.004
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 8/58 (13%)
Query: 48 CSDSS--DEDPTVCT-----ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDE 98
C+D+ DE+ T CT A +C+ F C + CI W+CD DC DGSDE
Sbjct: 820 CADNQLLDENGTTCTFNPGEALPHICKAGEFRC-KNRHCIQARWKCDGDDDCLDGSDE 876
Score = 41.1 bits (92), Expect = 0.014
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C EF C+ + C+ W CD + DC DGSDE + N
Sbjct: 845 CKAGEFRCKNR--HCIQARWKCDGDDDCLDGSDEDSVN 880
Score = 40.7 bits (91), Expect = 0.019
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNC 307
C+ +F+CK+ CI C+G DC DGSDE NC
Sbjct: 845 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNC 881
Score = 31.9 bits (69), Expect = 8.8
Identities = 13/38 (34%), Positives = 19/38 (50%)
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRW 163
+ D+N + +A C++ EF C N CIQ RW
Sbjct: 825 LLDENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARW 862
>AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein.
Length = 425
Score = 243 bits (594), Expect = 2e-63
Identities = 148/435 (34%), Positives = 210/435 (48%), Gaps = 25/435 (5%)
Query: 145 TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTDGQ-CISA 201
+C ++F C KCI W+ E C TC FSC + C+
Sbjct: 2 SCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADM-FSCQGSRACVPR 60
Query: 202 WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXX 261
W CDG+ DC DGSDE+ + C F C++++ C+ + +V
Sbjct: 61 HWLCDGERDCPDGSDELSTAGCAP-NNTCDENAFMCHNKV-CIPKQFVCDHDDDCGDGSD 118
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALY-CNGVKDCPDGSDEY----NCTRQKTICDK 316
E+ + C G C ++F C D C+ + C+G DCPD SDE C + C+
Sbjct: 119 ESPQ-C-GYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNS 176
Query: 317 RTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC-EKNNGGCSQRCVDTPIGYY 375
+ F C G CIP +CD DC + DE C NEC K GCSQ C D P+ Y
Sbjct: 177 -SFFMCKNGRCIPSGGLCDNKDDCGDGSDERN--CHINECLSKKVSGCSQDCQDLPVSYK 233
Query: 376 CDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA- 433
C C G++L D+ +TC DIDEC+ CSQ CIN GT+KC C GY P + CK+
Sbjct: 234 CKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQPDNPNGCKSL 293
Query: 434 TEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSD---VNDEKI 490
++ P L+ A H+IRKIS D + + A+D+ +R I+W D N +I
Sbjct: 294 SDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRI 353
Query: 491 YKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRD 550
+ ++ G+ VV + LAVDW+ +LYW+DT IE+S L G IL+
Sbjct: 354 NRMCLN-GSDIKVV--HNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSK 410
Query: 551 RLEEPRAIALNPLEG 565
RL+ PR ++L+P G
Sbjct: 411 RLKFPRDLSLDPQAG 425
Score = 147 bits (357), Expect = 1e-34
Identities = 77/212 (36%), Positives = 102/212 (48%), Gaps = 18/212 (8%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
+C+ ++F C +CI W CD E DC D DE ++C A + C F C C+P
Sbjct: 2 SCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGA--ITCAADMFSCQGSRACVP 59
Query: 82 RSWRCDATADCPDGSDEHQ---CEV-EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
R W CD DCPDGSDE C C F C K C+P ++CD + DC DGS
Sbjct: 60 RHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNK--VCIPKQFVCDHDDDCGDGS 117
Query: 138 DEK-ACN-ETCRSDEFTCGNGKC-IQMRWVXXXXXXXXXXXXEV----KCPT--PTCQPQ 188
DE C C ++EF+C +G+C + +W E KC + +C
Sbjct: 118 DESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCN-S 176
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
S F C +G+CI + CD DC DGSDE C
Sbjct: 177 SFFMCKNGRCIPSGGLCDNKDDCGDGSDERNC 208
Score = 121 bits (292), Expect = 8e-27
Identities = 121/439 (27%), Positives = 191/439 (43%), Gaps = 45/439 (10%)
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
+ F+C+ +CIS W CDG+ DC DG DE + C + F C CV R W
Sbjct: 6 NQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAIT---CAADMFSCQGSRACVPRHW 62
Query: 249 VXXXXXXXXXXXXEALEL-CRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEY-N 306
+ E C N TC + F C + CIP C+ DC DGSDE
Sbjct: 63 LCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQ 122
Query: 307 CTRQKTICDKRTEFDCGGGMCIPLSK-VCDKHVDCPNFEDE----PRDRCGENECEKNNG 361
C ++ C EF C G C+ ++ CD DCP+ DE P+ + E C +
Sbjct: 123 CGYRQ--CGTE-EFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFF 179
Query: 362 GCSQ-RCVDTPIGYYCD----CEKGYKLIDNRTCEDIDECADP--GSCSQICINEKGTFK 414
C RC+ P G CD C G D R C I+EC CSQ C + ++K
Sbjct: 180 MCKNGRCI--PSGGLCDNKDDCGDGS---DERNCH-INECLSKKVSGCSQDCQDLPVSYK 233
Query: 415 CECHTGYARDPRDRTRCKATE---GHP-SLLFARKHDIRK-ISLDHHEMVAIVNDTKSAT 469
C+C G+ +T E G P S + K + D +E + N +
Sbjct: 234 CKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYE-IQPDNPNGCKS 292
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNH--LYWT 527
D + +D ++ I K D G+ T++ +Q + ++ +A+D+ Y +YW
Sbjct: 293 LSD---EEPFLILADHHE--IRKISTD-GSNYTLL--KQGL-NNVIAIDFDYREEFIYWI 343
Query: 528 DTGH-NHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGS 586
D+ N ++ + N I + P A+A++ + ++W+D + IE + ++G
Sbjct: 344 DSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDT-EKRIIEVSKLNGL 402
Query: 587 HRSTIVSYDVKWPNGLTLD 605
+ + +VS +K+P L+LD
Sbjct: 403 YPTILVSKRLKFPRDLSLD 421
Score = 99 bits (238), Expect = 3e-20
Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 13/131 (9%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
+ TC + F C CIP + CD++ DC D SDE P C + C F C +DG C
Sbjct: 85 NNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQ-CGYRQ--CGTEEFSC-ADGRC 140
Query: 80 IPRS-WRCDATADCPDGSDE----HQCE--VEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
+ + W+CD DCPD SDE +C+ ++C F C K G C+P +CD+ D
Sbjct: 141 LLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMC--KNGRCIPSGGLCDNKDD 198
Query: 133 CSDGSDEKACN 143
C DGSDE+ C+
Sbjct: 199 CGDGSDERNCH 209
Score = 87.8 bits (208), Expect = 1e-16
Identities = 48/143 (33%), Positives = 67/143 (46%), Gaps = 6/143 (4%)
Query: 21 RTCTSSEFRCKTGRCI-PLSWKCDNEKDCSDSSDEDPT--VCTATKMVCQEYRFECLSDG 77
R C + EF C GRC+ W+CD + DC D SDE P C + + C F C +G
Sbjct: 126 RQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMC-KNG 184
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP CD DC DGSDE C + C ++ + + + +P+++ C P
Sbjct: 185 RCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKD 244
Query: 138 DEKACNETCR-SDEFTCGNGKCI 159
D K C + S F C +CI
Sbjct: 245 DGKTCVDIDECSSGFPCSQ-QCI 266
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S ++C SS F CK GRCIP CDN+ DC D SDE C + + ++ C D
Sbjct: 169 SAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE--RNCHINECLSKKVS-GCSQDC 225
Query: 78 LCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTC 113
+P S++C D C +++ C F C
Sbjct: 226 QDLPVSYKCKCWPGFQLKDDGKTCVDIDECS-SGFPC 261
Score = 33.1 bits (72), Expect = 3.8
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 531 HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQV--PKIERAGMDGSHR 588
H+ I G+ L++ L AI + E +++W D + +I R ++GS
Sbjct: 305 HHEIRKISTDGS-NYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNGSDI 363
Query: 589 STIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDG 628
+ ++ PN L +D + + +YW D + I +G
Sbjct: 364 KVV--HNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNG 401
>X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for
kidney epidermal growth factor (EGF) precursor. ).
Length = 1207
Score = 242 bits (592), Expect = 4e-63
Identities = 137/395 (34%), Positives = 205/395 (51%), Gaps = 17/395 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICIN-EKGTF 413
C +N CS CV T G C C +G L D +TC D G CSQ+C+ ++
Sbjct: 401 CPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSS-PDNGGCSQLCVPLSPVSW 459
Query: 414 KCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSAT-ALD 472
+C+C GY D C A+ P LLFA DIR + D + +++ ALD
Sbjct: 460 ECDCFPGYDLQ-LDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALD 518
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
+ I+++ + I +A +D G+QR +I E + +GLAVDW+ YWTD G +
Sbjct: 519 HDPVENKIYFAHTALKWIERANMD-GSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKS 577
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I SDL G KI+ ++ + +PR IA++P+ +FWTD G P+IE + + G R I
Sbjct: 578 LIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIA 637
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S D+ WP+G+T+D + ++YW DAK + I N DGS RR + + + HPF++ FED
Sbjct: 638 SSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQND--VGHPFAVAVFED 695
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+V+++DW +V R NK GKD + ++ P + V HP +P G + C NG C
Sbjct: 696 YVWFSDWAMPSVIRVNKRTGKD--RVRLQGSMLKPSSLVVVHPLAKP-GADPCLYQNGGC 752
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
H+C R G C+C G D + C+
Sbjct: 753 EHIC--KKRLG----TAWCSCREGFMKASDGKTCL 781
Score = 111 bits (267), Expect = 9e-24
Identities = 79/331 (23%), Positives = 159/331 (48%), Gaps = 28/331 (8%)
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
P L+F+ + I +I + +V D + +D+ + I+W D+ + + + ++
Sbjct: 46 PFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNG 105
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
Q V E+ ++ G+A++W+ + W++ I ++D++GN IL+ L+ P
Sbjct: 106 SRQERVCNIEKNVS--GMAINWINEEVIWSNQQEGIITVTDMKGNNSHILL-SALKYPAN 162
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV--- 614
+A++P+E ++FW+ + RA +DG ++ K ++LD++ +R++W+
Sbjct: 163 VAVDPVERFIFWSS-EVAGSLYRADLDGVGVKALLETSEKI-TAVSLDVLDKRLFWIQYN 220
Query: 615 -DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
+ + I SC+YDG + H T+ + F+++ F D ++++ W ++ ANK GK
Sbjct: 221 REGSNSLICSCDYDGGSVHISKHPTQ--HNLFAMSLFGDRIFYSTWKMKTIWIANKHTGK 278
Query: 674 DVEAITSTHTLQNPM-VIHVYHPYRQPDGVNH--------CAAVNGHCSH-LCLPAPRFG 723
D+ I + H+ P+ + V HP QP + C G+CS +C G
Sbjct: 279 DMVRI-NLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVC------G 331
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHF 754
+ C C G L D + C + ++ F
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAF 362
Score = 109 bits (263), Expect = 3e-23
Identities = 93/358 (25%), Positives = 159/358 (44%), Gaps = 19/358 (5%)
Query: 348 RDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSC 402
RDR C + NEC N GC+ C +TP YYC C G+ L+ D + C + C + C
Sbjct: 349 RDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC 408
Query: 403 SQICINEKGTFKCECHTG--YARDPRDRTRCKATE-GHPSLLFARKHDIRKISLDHHEMV 459
S C+ C C G RD + + C + + G S L + D
Sbjct: 409 SHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPV-SWECDCFPGY 467
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
+ D KS A + ++F N + I D GT ++ +Q+ L D
Sbjct: 468 DLQLDEKSCAASGP--QPFLLF---ANSQDIRHMHFD-GTDYGTLLSQQMGMVYALDHDP 521
Query: 520 VYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIE 579
V N +Y+ T IE +++ G+ R+ LI + ++ P +A++ + +WTD G+ I
Sbjct: 522 VENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGK-SLIG 580
Query: 580 RAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMN-TISSCNYDGSGRRLILHST 638
R+ ++G I ++ P G+ + + +R++W D +N I S + G GR +I S
Sbjct: 581 RSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSD 640
Query: 639 EVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ +I D +YW D ++ + AN +G +T + + +P + V+ Y
Sbjct: 641 LIWPSGITIDFLTDKLYWCDAKQSVIEMAN-LDGSKRRRLTQ-NDVGHPFAVAVFEDY 696
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/310 (22%), Positives = 119/310 (38%), Gaps = 23/310 (7%)
Query: 448 IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGE 507
++++ L+ + N K+ + + + + WS+ E I +G +++
Sbjct: 98 LQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSN-QQEGIITVTDMKGNNSHILLSA 156
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
++ +AVD V ++W+ + +DL G K L+ + E+ A++L+ L+ +
Sbjct: 157 LKYPAN-VAVDPVERFIFWSSEVAGSLYRADLDGVGVKALL-ETSEKITAVSLDVLDKRL 214
Query: 568 FWTDW---GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
FW + G I DG S +S N + L R+++ KM TI
Sbjct: 215 FWIQYNREGSNSLICSCDYDGG--SVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIA 272
Query: 625 N-YDGSGR-RLILHSTEV------LRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVE 676
N + G R+ LHS+ V + HP + ED W K R +
Sbjct: 273 NKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDT-WEPEQKLCKLRKGNCSSTVCG 331
Query: 677 AITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNG 736
+H + + + VN CA N C+ C P C CP G
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPG------SYYCTCPVG 385
Query: 737 LKLLPDDQMC 746
LLPD + C
Sbjct: 386 FVLLPDGKRC 395
Score = 47.6 bits (108), Expect = 2e-04
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Query: 354 NECEKNNGGC---SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICI 407
+ECE C S +C++T GY C C +GY+ D C DIDEC SC + C
Sbjct: 872 DECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCT 930
Query: 408 NEKGTFKCEC 417
N +G + C C
Sbjct: 931 NTEGGYTCMC 940
Score = 46.0 bits (104), Expect = 5e-04
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 9/70 (12%)
Query: 362 GCSQ--RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-----ADPGSCSQICINEKGTFK 414
GCS RC+ C C KG+ D + C DIDEC P + S+ CIN +G +
Sbjct: 839 GCSMYARCISEGEDATCQCLKGFAG-DGKLCSDIDECEMGVPVCPPASSK-CINTEGGYV 896
Query: 415 CECHTGYARD 424
C C GY D
Sbjct: 897 CRCSEGYQGD 906
Score = 34.3 bits (75), Expect = 1.6
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDID 394
P + G + C NGGC C +C C +G+ K D +TC +D
Sbjct: 736 PLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 242 bits (592), Expect = 4e-63
Identities = 137/395 (34%), Positives = 205/395 (51%), Gaps = 17/395 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICIN-EKGTF 413
C +N CS CV T G C C +G L D +TC D G CSQ+C+ ++
Sbjct: 401 CPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSS-PDNGGCSQLCVPLSPVSW 459
Query: 414 KCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSAT-ALD 472
+C+C GY D C A+ P LLFA DIR + D + +++ ALD
Sbjct: 460 ECDCFPGYDLQ-LDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALD 518
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
+ I+++ + I +A +D G+QR +I E + +GLAVDW+ YWTD G +
Sbjct: 519 HDPVENKIYFAHTALKWIERANMD-GSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKS 577
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I SDL G KI+ ++ + +PR IA++P+ +FWTD G P+IE + + G R I
Sbjct: 578 LIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIA 637
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S D+ WP+G+T+D + ++YW DAK + I N DGS RR + + + HPF++ FED
Sbjct: 638 SSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQND--VGHPFAVAVFED 695
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+V+++DW +V R NK GKD + ++ P + V HP +P G + C NG C
Sbjct: 696 YVWFSDWAMPSVIRVNKRTGKD--RVRLQGSMLKPSSLVVVHPLAKP-GADPCLYQNGGC 752
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
H+C R G C+C G D + C+
Sbjct: 753 EHIC--KKRLG----TAWCSCREGFMKASDGKTCL 781
Score = 111 bits (267), Expect = 9e-24
Identities = 79/331 (23%), Positives = 159/331 (48%), Gaps = 28/331 (8%)
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
P L+F+ + I +I + +V D + +D+ + I+W D+ + + + ++
Sbjct: 46 PFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNG 105
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
Q V E+ ++ G+A++W+ + W++ I ++D++GN IL+ L+ P
Sbjct: 106 SRQERVCNIEKNVS--GMAINWINEEVIWSNQQEGIITVTDMKGNNSHILL-SALKYPAN 162
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV--- 614
+A++P+E ++FW+ + RA +DG ++ K ++LD++ +R++W+
Sbjct: 163 VAVDPVERFIFWSS-EVAGSLYRADLDGVGVKALLETSEKI-TAVSLDVLDKRLFWIQYN 220
Query: 615 -DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
+ + I SC+YDG + H T+ + F+++ F D ++++ W ++ ANK GK
Sbjct: 221 REGSNSLICSCDYDGGSVHISKHPTQ--HNLFAMSLFGDRIFYSTWKMKTIWIANKHTGK 278
Query: 674 DVEAITSTHTLQNPM-VIHVYHPYRQPDGVNH--------CAAVNGHCSH-LCLPAPRFG 723
D+ I + H+ P+ + V HP QP + C G+CS +C G
Sbjct: 279 DMVRI-NLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVC------G 331
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHF 754
+ C C G L D + C + ++ F
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAF 362
Score = 109 bits (263), Expect = 3e-23
Identities = 93/358 (25%), Positives = 159/358 (44%), Gaps = 19/358 (5%)
Query: 348 RDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSC 402
RDR C + NEC N GC+ C +TP YYC C G+ L+ D + C + C + C
Sbjct: 349 RDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC 408
Query: 403 SQICINEKGTFKCECHTG--YARDPRDRTRCKATE-GHPSLLFARKHDIRKISLDHHEMV 459
S C+ C C G RD + + C + + G S L + D
Sbjct: 409 SHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPV-SWECDCFPGY 467
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
+ D KS A + ++F N + I D GT ++ +Q+ L D
Sbjct: 468 DLQLDEKSCAASGP--QPFLLF---ANSQDIRHMHFD-GTDYGTLLSQQMGMVYALDHDP 521
Query: 520 VYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIE 579
V N +Y+ T IE +++ G+ R+ LI + ++ P +A++ + +WTD G+ I
Sbjct: 522 VENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGK-SLIG 580
Query: 580 RAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMN-TISSCNYDGSGRRLILHST 638
R+ ++G I ++ P G+ + + +R++W D +N I S + G GR +I S
Sbjct: 581 RSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSD 640
Query: 639 EVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ +I D +YW D ++ + AN +G +T + + +P + V+ Y
Sbjct: 641 LIWPSGITIDFLTDKLYWCDAKQSVIEMAN-LDGSKRRRLTQ-NDVGHPFAVAVFEDY 696
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/310 (22%), Positives = 119/310 (38%), Gaps = 23/310 (7%)
Query: 448 IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGE 507
++++ L+ + N K+ + + + + WS+ E I +G +++
Sbjct: 98 LQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSN-QQEGIITVTDMKGNNSHILLSA 156
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
++ +AVD V ++W+ + +DL G K L+ + E+ A++L+ L+ +
Sbjct: 157 LKYPAN-VAVDPVERFIFWSSEVAGSLYRADLDGVGVKALL-ETSEKITAVSLDVLDKRL 214
Query: 568 FWTDW---GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
FW + G I DG S +S N + L R+++ KM TI
Sbjct: 215 FWIQYNREGSNSLICSCDYDGG--SVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIA 272
Query: 625 N-YDGSGR-RLILHSTEV------LRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVE 676
N + G R+ LHS+ V + HP + ED W K R +
Sbjct: 273 NKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDT-WEPEQKLCKLRKGNCSSTVCG 331
Query: 677 AITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNG 736
+H + + + VN CA N C+ C P C CP G
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPG------SYYCTCPVG 385
Query: 737 LKLLPDDQMC 746
LLPD + C
Sbjct: 386 FVLLPDGKRC 395
Score = 47.6 bits (108), Expect = 2e-04
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Query: 354 NECEKNNGGC---SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICI 407
+ECE C S +C++T GY C C +GY+ D C DIDEC SC + C
Sbjct: 872 DECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCT 930
Query: 408 NEKGTFKCEC 417
N +G + C C
Sbjct: 931 NTEGGYTCMC 940
Score = 46.0 bits (104), Expect = 5e-04
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 9/70 (12%)
Query: 362 GCSQ--RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-----ADPGSCSQICINEKGTFK 414
GCS RC+ C C KG+ D + C DIDEC P + S+ CIN +G +
Sbjct: 839 GCSMYARCISEGEDATCQCLKGFAG-DGKLCSDIDECEMGVPVCPPASSK-CINTEGGYV 896
Query: 415 CECHTGYARD 424
C C GY D
Sbjct: 897 CRCSEGYQGD 906
Score = 34.3 bits (75), Expect = 1.6
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDID 394
P + G + C NGGC C +C C +G+ K D +TC +D
Sbjct: 736 PLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 242 bits (592), Expect = 4e-63
Identities = 137/395 (34%), Positives = 205/395 (51%), Gaps = 17/395 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICIN-EKGTF 413
C +N CS CV T G C C +G L D +TC D G CSQ+C+ ++
Sbjct: 401 CPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSS-PDNGGCSQLCVPLSPVSW 459
Query: 414 KCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSAT-ALD 472
+C+C GY D C A+ P LLFA DIR + D + +++ ALD
Sbjct: 460 ECDCFPGYDLQ-LDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALD 518
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
+ I+++ + I +A +D G+QR +I E + +GLAVDW+ YWTD G +
Sbjct: 519 HDPVENKIYFAHTALKWIERANMD-GSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKS 577
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I SDL G KI+ ++ + +PR IA++P+ +FWTD G P+IE + + G R I
Sbjct: 578 LIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIA 637
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S D+ WP+G+T+D + ++YW DAK + I N DGS RR + + + HPF++ FED
Sbjct: 638 SSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQND--VGHPFAVAVFED 695
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+V+++DW +V R NK GKD + ++ P + V HP +P G + C NG C
Sbjct: 696 YVWFSDWAMPSVIRVNKRTGKD--RVRLQGSMLKPSSLVVVHPLAKP-GADPCLYQNGGC 752
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
H+C R G C+C G D + C+
Sbjct: 753 EHIC--KKRLG----TAWCSCREGFMKASDGKTCL 781
Score = 111 bits (267), Expect = 9e-24
Identities = 79/331 (23%), Positives = 159/331 (48%), Gaps = 28/331 (8%)
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
P L+F+ + I +I + +V D + +D+ + I+W D+ + + + ++
Sbjct: 46 PFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNG 105
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
Q V E+ ++ G+A++W+ + W++ I ++D++GN IL+ L+ P
Sbjct: 106 SRQERVCNIEKNVS--GMAINWINEEVIWSNQQEGIITVTDMKGNNSHILL-SALKYPAN 162
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV--- 614
+A++P+E ++FW+ + RA +DG ++ K ++LD++ +R++W+
Sbjct: 163 VAVDPVERFIFWSS-EVAGSLYRADLDGVGVKALLETSEKI-TAVSLDVLDKRLFWIQYN 220
Query: 615 -DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
+ + I SC+YDG + H T+ + F+++ F D ++++ W ++ ANK GK
Sbjct: 221 REGSNSLICSCDYDGGSVHISKHPTQ--HNLFAMSLFGDRIFYSTWKMKTIWIANKHTGK 278
Query: 674 DVEAITSTHTLQNPM-VIHVYHPYRQPDGVNH--------CAAVNGHCSH-LCLPAPRFG 723
D+ I + H+ P+ + V HP QP + C G+CS +C G
Sbjct: 279 DMVRI-NLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVC------G 331
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHF 754
+ C C G L D + C + ++ F
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAF 362
Score = 109 bits (263), Expect = 3e-23
Identities = 93/358 (25%), Positives = 159/358 (44%), Gaps = 19/358 (5%)
Query: 348 RDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSC 402
RDR C + NEC N GC+ C +TP YYC C G+ L+ D + C + C + C
Sbjct: 349 RDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC 408
Query: 403 SQICINEKGTFKCECHTG--YARDPRDRTRCKATE-GHPSLLFARKHDIRKISLDHHEMV 459
S C+ C C G RD + + C + + G S L + D
Sbjct: 409 SHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPV-SWECDCFPGY 467
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
+ D KS A + ++F N + I D GT ++ +Q+ L D
Sbjct: 468 DLQLDEKSCAASGP--QPFLLF---ANSQDIRHMHFD-GTDYGTLLSQQMGMVYALDHDP 521
Query: 520 VYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIE 579
V N +Y+ T IE +++ G+ R+ LI + ++ P +A++ + +WTD G+ I
Sbjct: 522 VENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGK-SLIG 580
Query: 580 RAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMN-TISSCNYDGSGRRLILHST 638
R+ ++G I ++ P G+ + + +R++W D +N I S + G GR +I S
Sbjct: 581 RSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSD 640
Query: 639 EVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ +I D +YW D ++ + AN +G +T + + +P + V+ Y
Sbjct: 641 LIWPSGITIDFLTDKLYWCDAKQSVIEMAN-LDGSKRRRLTQ-NDVGHPFAVAVFEDY 696
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/310 (22%), Positives = 119/310 (38%), Gaps = 23/310 (7%)
Query: 448 IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGE 507
++++ L+ + N K+ + + + + WS+ E I +G +++
Sbjct: 98 LQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSN-QQEGIITVTDMKGNNSHILLSA 156
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
++ +AVD V ++W+ + +DL G K L+ + E+ A++L+ L+ +
Sbjct: 157 LKYPAN-VAVDPVERFIFWSSEVAGSLYRADLDGVGVKALL-ETSEKITAVSLDVLDKRL 214
Query: 568 FWTDW---GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
FW + G I DG S +S N + L R+++ KM TI
Sbjct: 215 FWIQYNREGSNSLICSCDYDGG--SVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIA 272
Query: 625 N-YDGSGR-RLILHSTEV------LRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVE 676
N + G R+ LHS+ V + HP + ED W K R +
Sbjct: 273 NKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDT-WEPEQKLCKLRKGNCSSTVCG 331
Query: 677 AITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNG 736
+H + + + VN CA N C+ C P C CP G
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPG------SYYCTCPVG 385
Query: 737 LKLLPDDQMC 746
LLPD + C
Sbjct: 386 FVLLPDGKRC 395
Score = 47.6 bits (108), Expect = 2e-04
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Query: 354 NECEKNNGGC---SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICI 407
+ECE C S +C++T GY C C +GY+ D C DIDEC SC + C
Sbjct: 872 DECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCT 930
Query: 408 NEKGTFKCEC 417
N +G + C C
Sbjct: 931 NTEGGYTCMC 940
Score = 46.0 bits (104), Expect = 5e-04
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 9/70 (12%)
Query: 362 GCSQ--RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-----ADPGSCSQICINEKGTFK 414
GCS RC+ C C KG+ D + C DIDEC P + S+ CIN +G +
Sbjct: 839 GCSMYARCISEGEDATCQCLKGFAG-DGKLCSDIDECEMGVPVCPPASSK-CINTEGGYV 896
Query: 415 CECHTGYARD 424
C C GY D
Sbjct: 897 CRCSEGYQGD 906
Score = 34.3 bits (75), Expect = 1.6
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDID 394
P + G + C NGGC C +C C +G+ K D +TC +D
Sbjct: 736 PLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal growth
factor (beta-urogastrone) protein.
Length = 1152
Score = 242 bits (592), Expect = 4e-63
Identities = 137/395 (34%), Positives = 205/395 (51%), Gaps = 17/395 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICIN-EKGTF 413
C +N CS CV T G C C +G L D +TC D G CSQ+C+ ++
Sbjct: 401 CPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSS-PDNGGCSQLCVPLSPVSW 459
Query: 414 KCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDHHEMVAIVNDTKSAT-ALD 472
+C+C GY D C A+ P LLFA DIR + D + +++ ALD
Sbjct: 460 ECDCFPGYDLQ-LDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALD 518
Query: 473 YVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHN 532
+ I+++ + I +A +D G+QR +I E + +GLAVDW+ YWTD G +
Sbjct: 519 HDPVENKIYFAHTALKWIERANMD-GSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKS 577
Query: 533 HIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I SDL G KI+ ++ + +PR IA++P+ +FWTD G P+IE + + G R I
Sbjct: 578 LIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIA 637
Query: 593 SYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFED 652
S D+ WP+G+T+D + ++YW DAK + I N DGS RR + + + HPF++ FED
Sbjct: 638 SSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQND--VGHPFAVAVFED 695
Query: 653 WVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHC 712
+V+++DW +V R NK GKD + ++ P + V HP +P G + C NG C
Sbjct: 696 YVWFSDWAMPSVIRVNKRTGKD--RVRLQGSMLKPSSLVVVHPLAKP-GADPCLYQNGGC 752
Query: 713 SHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCV 747
H+C R G C+C G D + C+
Sbjct: 753 EHIC--KKRLG----TAWCSCREGFMKASDGKTCL 781
Score = 111 bits (267), Expect = 9e-24
Identities = 79/331 (23%), Positives = 159/331 (48%), Gaps = 28/331 (8%)
Query: 438 PSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
P L+F+ + I +I + +V D + +D+ + I+W D+ + + + ++
Sbjct: 46 PFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNG 105
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRA 557
Q V E+ ++ G+A++W+ + W++ I ++D++GN IL+ L+ P
Sbjct: 106 SRQERVCNIEKNVS--GMAINWINEEVIWSNQQEGIITVTDMKGNNSHILL-SALKYPAN 162
Query: 558 IALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWV--- 614
+A++P+E ++FW+ + RA +DG ++ K ++LD++ +R++W+
Sbjct: 163 VAVDPVERFIFWSS-EVAGSLYRADLDGVGVKALLETSEKI-TAVSLDVLDKRLFWIQYN 220
Query: 615 -DAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGK 673
+ + I SC+YDG + H T+ + F+++ F D ++++ W ++ ANK GK
Sbjct: 221 REGSNSLICSCDYDGGSVHISKHPTQ--HNLFAMSLFGDRIFYSTWKMKTIWIANKHTGK 278
Query: 674 DVEAITSTHTLQNPM-VIHVYHPYRQPDGVNH--------CAAVNGHCSH-LCLPAPRFG 723
D+ I + H+ P+ + V HP QP + C G+CS +C G
Sbjct: 279 DMVRI-NLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVC------G 331
Query: 724 PNSPRVSCACPNGLKLLPDDQMCVEDSKYHF 754
+ C C G L D + C + ++ F
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAF 362
Score = 109 bits (263), Expect = 3e-23
Identities = 93/358 (25%), Positives = 159/358 (44%), Gaps = 19/358 (5%)
Query: 348 RDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSC 402
RDR C + NEC N GC+ C +TP YYC C G+ L+ D + C + C + C
Sbjct: 349 RDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSEC 408
Query: 403 SQICINEKGTFKCECHTG--YARDPRDRTRCKATE-GHPSLLFARKHDIRKISLDHHEMV 459
S C+ C C G RD + + C + + G S L + D
Sbjct: 409 SHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPV-SWECDCFPGY 467
Query: 460 AIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDW 519
+ D KS A + ++F N + I D GT ++ +Q+ L D
Sbjct: 468 DLQLDEKSCAASGP--QPFLLF---ANSQDIRHMHFD-GTDYGTLLSQQMGMVYALDHDP 521
Query: 520 VYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIE 579
V N +Y+ T IE +++ G+ R+ LI + ++ P +A++ + +WTD G+ I
Sbjct: 522 VENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGK-SLIG 580
Query: 580 RAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMN-TISSCNYDGSGRRLILHST 638
R+ ++G I ++ P G+ + + +R++W D +N I S + G GR +I S
Sbjct: 581 RSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSD 640
Query: 639 EVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPY 696
+ +I D +YW D ++ + AN +G +T + + +P + V+ Y
Sbjct: 641 LIWPSGITIDFLTDKLYWCDAKQSVIEMAN-LDGSKRRRLTQ-NDVGHPFAVAVFEDY 696
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/310 (22%), Positives = 119/310 (38%), Gaps = 23/310 (7%)
Query: 448 IRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGE 507
++++ L+ + N K+ + + + + WS+ E I +G +++
Sbjct: 98 LQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSN-QQEGIITVTDMKGNNSHILLSA 156
Query: 508 QLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWM 567
++ +AVD V ++W+ + +DL G K L+ + E+ A++L+ L+ +
Sbjct: 157 LKYPAN-VAVDPVERFIFWSSEVAGSLYRADLDGVGVKALL-ETSEKITAVSLDVLDKRL 214
Query: 568 FWTDW---GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSC 624
FW + G I DG S +S N + L R+++ KM TI
Sbjct: 215 FWIQYNREGSNSLICSCDYDGG--SVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIA 272
Query: 625 N-YDGSGR-RLILHSTEV------LRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVE 676
N + G R+ LHS+ V + HP + ED W K R +
Sbjct: 273 NKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDT-WEPEQKLCKLRKGNCSSTVCG 331
Query: 677 AITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNG 736
+H + + + VN CA N C+ C P C CP G
Sbjct: 332 QDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPG------SYYCTCPVG 385
Query: 737 LKLLPDDQMC 746
LLPD + C
Sbjct: 386 FVLLPDGKRC 395
Score = 47.6 bits (108), Expect = 2e-04
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Query: 354 NECEKNNGGC---SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICI 407
+ECE C S +C++T GY C C +GY+ D C DIDEC SC + C
Sbjct: 872 DECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ-GDGIHCLDIDECQLGVHSCGENASCT 930
Query: 408 NEKGTFKCEC 417
N +G + C C
Sbjct: 931 NTEGGYTCMC 940
Score = 46.0 bits (104), Expect = 5e-04
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 9/70 (12%)
Query: 362 GCSQ--RCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-----ADPGSCSQICINEKGTFK 414
GCS RC+ C C KG+ D + C DIDEC P + S+ CIN +G +
Sbjct: 839 GCSMYARCISEGEDATCQCLKGFAG-DGKLCSDIDECEMGVPVCPPASSK-CINTEGGYV 896
Query: 415 CECHTGYARD 424
C C GY D
Sbjct: 897 CRCSEGYQGD 906
Score = 34.3 bits (75), Expect = 1.6
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDID 394
P + G + C NGGC C +C C +G+ K D +TC +D
Sbjct: 736 PLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein.
Length = 439
Score = 234 bits (572), Expect = 1e-60
Identities = 133/382 (34%), Positives = 204/382 (53%), Gaps = 20/382 (5%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVNDE------KIYKAPI 495
A +I L ++ I T+ TA+D+ + + W V D K + P
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPG 263
Query: 496 DEG--TQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLE 553
+G + T+ I L + +A+DW+ + Y+ D + I + + G+ L+ L
Sbjct: 264 LKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELY 323
Query: 554 EPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYW 613
P+ IAL+P G +F+TD+GQ+PK+ER MDG +R+ +V + +P+G+TLDLV + VYW
Sbjct: 324 NPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYW 383
Query: 614 VDAKMNTISSCNYDGSGRRLIL 635
DA ++ I +Y+G GR+ I+
Sbjct: 384 ADAYLDYIEVVDYEGKGRQTII 405
Score = 91.1 bits (216), Expect = 1e-17
Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 37/397 (9%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECADPGSCSQICINEK--GTFKCECHT----------------GYARDPRDRTRCKATEG 436
E D I ++ T+ YA + +
Sbjct: 193 EPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAA 252
Query: 437 HPSLLFARKHDIRKISLDHHEMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPID 496
L AR ++ +H +++ A+D++ TG ++ D D++I+
Sbjct: 253 QTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWL--TGNFYFVDDIDDRIFVCN-R 309
Query: 497 EGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGH-NHIELSDLQGNMRKILIRDRLEEP 555
G ++ +L G+A+D +++TD G +E D+ G R L+ ++ P
Sbjct: 310 NGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFP 369
Query: 556 RAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIV 592
I L+ + ++W D + IE +G R TI+
Sbjct: 370 HGITLDLVSRLVYWAD-AYLDYIEVVDYEGKGRQTII 405
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 41.9 bits (94), Expect = 0.008
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 478 GMIFWSDVND-EKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIEL 536
G +F++D K+ + +D G RT ++ +++ G+ +D V +YW D ++IE+
Sbjct: 335 GKVFFTDYGQIPKVERCDMD-GQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEV 393
Query: 537 SDLQGNMRKILIR 549
D +G R+ +I+
Sbjct: 394 VDYEGKGRQTIIQ 406
Score = 38.7 bits (86), Expect = 0.076
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 590 TIVSYDVKWPNGLTLDLVRQRVYWVD-AKMNTISSCNYDGSGRRLILHSTEVLRHPFSIT 648
T++ ++ P G+ LD +V++ D ++ + C+ DG R ++ S V H ++
Sbjct: 316 TLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLD 375
Query: 649 TFEDWVYWTD 658
VYW D
Sbjct: 376 LVSRLVYWAD 385
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein.
Length = 2214
Score = 221 bits (539), Expect = 1e-56
Identities = 134/401 (33%), Positives = 182/401 (45%), Gaps = 34/401 (8%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQ-EYRFECLSDG 77
E TC +++RC G CI W CD + DC D SDE C T +C + +F C G
Sbjct: 1074 EENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERN--CPTT--ICDLDTQFRCQESG 1129
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP S++CD DC D SDE CE+ C +E+ C G C+ +W+CD + DC D S
Sbjct: 1130 TCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNC--SSGMCIRSSWVCDGDNDCRDWS 1187
Query: 138 DEKACN---ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH-FSC 193
DE C TC + F C NG CI RW E C+ + + F C
Sbjct: 1188 DEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDE---DPVNCEKKCNGFRC 1244
Query: 194 TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXX 253
+G CI + HCDG DC+DGSDE C P +F C +R C+ + V
Sbjct: 1245 PNGTCIPSSKHCDGLRDCSDGSDEQHC--EPLCTH---FMDFVCKNRQQCLFHSMVCDGI 1299
Query: 254 XXXXXXXXE--ALELC----RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E A C + C FQC++ CI C+G+ DC D SDE NC
Sbjct: 1300 IQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANC 1359
Query: 308 TR--QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+ C + +F C G CIP CD+ DC ++ DE +D CG++ +
Sbjct: 1360 ENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDE-KD-CGDSHILPFSTPGPS 1417
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC 406
C+ Y C G ++D C+ +CAD GS + C
Sbjct: 1418 TCLPN----YYRCSSGTCVMDTWVCDGYRDCAD-GSDEEAC 1453
Score = 208 bits (507), Expect = 7e-53
Identities = 128/358 (35%), Positives = 158/358 (44%), Gaps = 42/358 (11%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC +S F+C+ G CIP W CD + DC D SDEDP C + C +R C +G CIP
Sbjct: 1198 TCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNC---EKKCNGFR--C-PNGTCIP 1251
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
S CD DC DGSDE CE +F C+ + +C+ + +CD C DGSDE A
Sbjct: 1252 SSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQ-QCLFHSMVCDGIIQCRDGSDEDA 1310
Query: 142 CNETCRSDE----------FTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT----CQP 187
C D F C NG CI + W E C PT C
Sbjct: 1311 AFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSR 1370
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC-------VSTPKVRSPCISTEFECNDR 240
F C +G CI W CD + DC D SDE C STP S C+ + C+
Sbjct: 1371 YFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPG-PSTCLPNYYRCSSG 1429
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTC--------RLDQFQCKDH---SCIPGA 289
TCV WV E NVT R D+F+ + H +CIP
Sbjct: 1430 -TCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNW 1488
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDE 346
C+G +DC DG DE NC T+ EF C G CI LS+ CD +DC + DE
Sbjct: 1489 KRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDE 1546
Score = 182 bits (444), Expect = 3e-45
Identities = 109/322 (33%), Positives = 174/322 (54%), Gaps = 21/322 (6%)
Query: 431 CKATEGHPSLLFARKHDIRKISLDHHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEK 489
C E + +L+A + I + L + + ++A ALD+ + ++WSD+ +
Sbjct: 752 CPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDV 811
Query: 490 IYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIR 549
I + ++ T + V+I L T + LA + + LYW D G IE+++ G+ R ++
Sbjct: 812 IQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVN 871
Query: 550 DR-LEEPRAIALNPLEGWMFWTDWGQV-PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLV 607
L+ PRA+ L P EG MFWTDWG + P I R+ MDGS +VS DVKWPNG+++D
Sbjct: 872 SSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVD-- 929
Query: 608 RQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRA 667
Q +YW DA + I + G R +IL + L HP++I F++ +YW DW + +++RA
Sbjct: 930 DQWIYWTDAYLECIERITFSGQQRSVILDN---LPHPYAIAVFKNEIYWDDWSQLSIFRA 986
Query: 668 NKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSP 727
+K++G +E + + L M + +++ + G N C V CS LCLP N+
Sbjct: 987 SKYSGSQMEIL--ANQLTGLMDMKIFYKGKN-TGSNAC--VPRPCSLLCLPK----ANNS 1037
Query: 728 RVSCACPNGL--KLLPD-DQMC 746
R SC CP + +LP D MC
Sbjct: 1038 R-SCRCPEDVSSSVLPSGDLMC 1058
Score = 159 bits (386), Expect = 3e-38
Identities = 114/321 (35%), Positives = 140/321 (43%), Gaps = 42/321 (13%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLCIPRSWRC 86
FRC G CIP S CD +DCSD SDE C + +C + F C + C+ S C
Sbjct: 1242 FRCPNGTCIPSSKHCDGLRDCSDGSDEQH--C---EPLCTHFMDFVCKNRQQCLFHSMVC 1296
Query: 87 DATADCPDGSDEHQCEVEACG--PE------EFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
D C DGSDE C PE EF + + G C+ L W CD DC D SD
Sbjct: 1297 DGIIQCRDGSDE-DAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSD 1355
Query: 139 EKAC-NET----C-RSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC----------PT 182
E C N T C R +F C NG CI RW E C P
Sbjct: 1356 EANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPG 1415
Query: 183 P-TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC--------VSTPKVRSPCIST 233
P TC P +++ C+ G C+ W CDG DCADGSDE C STP C
Sbjct: 1416 PSTCLP-NYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRF 1474
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYC 292
EFEC+ TC+ EA +TC +FQC+D +CI + C
Sbjct: 1475 EFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERC 1534
Query: 293 NGVKDCPDGSDEYNCTRQKTI 313
+G DC D SDE C+ + T+
Sbjct: 1535 DGFLDCSDESDEKACSDELTV 1555
Score = 128 bits (309), Expect = 7e-29
Identities = 85/229 (37%), Positives = 99/229 (43%), Gaps = 31/229 (13%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGLC 79
+ C F+C+ G CI L WKCD DC D SDE C Y +F C +G C
Sbjct: 1323 KVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRC-ENGHC 1381
Query: 80 IPRSWRCDATADCPDGSDEHQCE----VEACGPEEFTC-----RGKPGECVPLTWMCDDN 130
IP W+CD DC D SDE C + P TC R G CV TW+CD
Sbjct: 1382 IPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGY 1441
Query: 131 PDCSDGSDEKAC----NET----------CRSDEFTCGNGKCIQMRWVXXXXXXX-XXXX 175
DC+DGSDE+AC N T C EF C K W
Sbjct: 1442 RDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGR 1501
Query: 176 XEVKCPTP---TCQPQSHFSCTDGQ-CISAWWHCDGDVDCADGSDEVGC 220
E CPT TC + F C DG+ CI CDG +DC+D SDE C
Sbjct: 1502 DEANCPTHSTLTCMSRE-FQCEDGEACIVLSERCDGFLDCSDESDEKAC 1549
Score = 105 bits (253), Expect = 4e-22
Identities = 57/147 (38%), Positives = 73/147 (49%), Gaps = 15/147 (10%)
Query: 11 HIYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMV--- 65
HI F TC + +RC +G C+ +W CD +DC+D SDE+ P + T
Sbjct: 1407 HILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPT 1466
Query: 66 ----CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPG 118
C + FEC CIP RCD DC DG DE C + C EF C + G
Sbjct: 1467 QLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQC--EDG 1524
Query: 119 E-CVPLTWMCDDNPDCSDGSDEKACNE 144
E C+ L+ CD DCSD SDEKAC++
Sbjct: 1525 EACIVLSERCDGFLDCSDESDEKACSD 1551
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/84 (40%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 23 CTSSEFRCKTGR-CIPLSWK-CDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
C EF C + CIP +WK CD +DC D DE T + + C F+C CI
Sbjct: 1471 CDRFEFECHQPKTCIP-NWKRCDGHQDCQDGRDE-ANCPTHSTLTCMSREFQCEDGEACI 1528
Query: 81 PRSWRCDATADCPDGSDEHQCEVE 104
S RCD DC D SDE C E
Sbjct: 1529 VLSERCDGFLDCSDESDEKACSDE 1552
>U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein.
Length = 2214
Score = 221 bits (539), Expect = 1e-56
Identities = 134/401 (33%), Positives = 182/401 (45%), Gaps = 34/401 (8%)
Query: 19 ESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQ-EYRFECLSDG 77
E TC +++RC G CI W CD + DC D SDE C T +C + +F C G
Sbjct: 1074 EENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERN--CPTT--ICDLDTQFRCQESG 1129
Query: 78 LCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGS 137
CIP S++CD DC D SDE CE+ C +E+ C G C+ +W+CD + DC D S
Sbjct: 1130 TCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNC--SSGMCIRSSWVCDGDNDCRDWS 1187
Query: 138 DEKACN---ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH-FSC 193
DE C TC + F C NG CI RW E C+ + + F C
Sbjct: 1188 DEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDE---DPVNCEKKCNGFRC 1244
Query: 194 TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXX 253
+G CI + HCDG DC+DGSDE C P +F C +R C+ + V
Sbjct: 1245 PNGTCIPSSKHCDGLRDCSDGSDEQHC--EPLCTH---FMDFVCKNRQQCLFHSMVCDGI 1299
Query: 254 XXXXXXXXE--ALELC----RGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E A C + C FQC++ CI C+G+ DC D SDE NC
Sbjct: 1300 IQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANC 1359
Query: 308 TR--QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ 365
+ C + +F C G CIP CD+ DC ++ DE +D CG++ +
Sbjct: 1360 ENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDE-KD-CGDSHILPFSTPGPS 1417
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC 406
C+ Y C G ++D C+ +CAD GS + C
Sbjct: 1418 TCLPN----YYRCSSGTCVMDTWVCDGYRDCAD-GSDEEAC 1453
Score = 208 bits (507), Expect = 7e-53
Identities = 128/358 (35%), Positives = 158/358 (44%), Gaps = 42/358 (11%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
TC +S F+C+ G CIP W CD + DC D SDEDP C + C +R C +G CIP
Sbjct: 1198 TCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNC---EKKCNGFR--C-PNGTCIP 1251
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
S CD DC DGSDE CE +F C+ + +C+ + +CD C DGSDE A
Sbjct: 1252 SSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQ-QCLFHSMVCDGIIQCRDGSDEDA 1310
Query: 142 CNETCRSDE----------FTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT----CQP 187
C D F C NG CI + W E C PT C
Sbjct: 1311 AFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSR 1370
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC-------VSTPKVRSPCISTEFECNDR 240
F C +G CI W CD + DC D SDE C STP S C+ + C+
Sbjct: 1371 YFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPG-PSTCLPNYYRCSSG 1429
Query: 241 ITCVHRAWVXXXXXXXXXXXXEALELCRGNVTC--------RLDQFQCKDH---SCIPGA 289
TCV WV E NVT R D+F+ + H +CIP
Sbjct: 1430 -TCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNW 1488
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVCDKHVDCPNFEDE 346
C+G +DC DG DE NC T+ EF C G CI LS+ CD +DC + DE
Sbjct: 1489 KRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDE 1546
Score = 182 bits (444), Expect = 3e-45
Identities = 109/322 (33%), Positives = 174/322 (54%), Gaps = 21/322 (6%)
Query: 431 CKATEGHPSLLFARKHDIRKISLDHHEMVAI-VNDTKSATALDYVFRTGMIFWSDVNDEK 489
C E + +L+A + I + L + + ++A ALD+ + ++WSD+ +
Sbjct: 752 CPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDV 811
Query: 490 IYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIR 549
I + ++ T + V+I L T + LA + + LYW D G IE+++ G+ R ++
Sbjct: 812 IQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVN 871
Query: 550 DR-LEEPRAIALNPLEGWMFWTDWGQV-PKIERAGMDGSHRSTIVSYDVKWPNGLTLDLV 607
L+ PRA+ L P EG MFWTDWG + P I R+ MDGS +VS DVKWPNG+++D
Sbjct: 872 SSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVD-- 929
Query: 608 RQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRA 667
Q +YW DA + I + G R +IL + L HP++I F++ +YW DW + +++RA
Sbjct: 930 DQWIYWTDAYLECIERITFSGQQRSVILDN---LPHPYAIAVFKNEIYWDDWSQLSIFRA 986
Query: 668 NKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSP 727
+K++G +E + + L M + +++ + G N C V CS LCLP N+
Sbjct: 987 SKYSGSQMEIL--ANQLTGLMDMKIFYKGKN-TGSNAC--VPRPCSLLCLPK----ANNS 1037
Query: 728 RVSCACPNGL--KLLPD-DQMC 746
R SC CP + +LP D MC
Sbjct: 1038 R-SCRCPEDVSSSVLPSGDLMC 1058
Score = 159 bits (386), Expect = 3e-38
Identities = 114/321 (35%), Positives = 140/321 (43%), Gaps = 42/321 (13%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYR-FECLSDGLCIPRSWRC 86
FRC G CIP S CD +DCSD SDE C + +C + F C + C+ S C
Sbjct: 1242 FRCPNGTCIPSSKHCDGLRDCSDGSDEQH--C---EPLCTHFMDFVCKNRQQCLFHSMVC 1296
Query: 87 DATADCPDGSDEHQCEVEACG--PE------EFTCRGKPGECVPLTWMCDDNPDCSDGSD 138
D C DGSDE C PE EF + + G C+ L W CD DC D SD
Sbjct: 1297 DGIIQCRDGSDE-DAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSD 1355
Query: 139 EKAC-NET----C-RSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC----------PT 182
E C N T C R +F C NG CI RW E C P
Sbjct: 1356 EANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPG 1415
Query: 183 P-TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC--------VSTPKVRSPCIST 233
P TC P +++ C+ G C+ W CDG DCADGSDE C STP C
Sbjct: 1416 PSTCLP-NYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPTQLGRCDRF 1474
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYC 292
EFEC+ TC+ EA +TC +FQC+D +CI + C
Sbjct: 1475 EFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERC 1534
Query: 293 NGVKDCPDGSDEYNCTRQKTI 313
+G DC D SDE C+ + T+
Sbjct: 1535 DGFLDCSDESDEKACSDELTV 1555
Score = 128 bits (309), Expect = 7e-29
Identities = 85/229 (37%), Positives = 99/229 (43%), Gaps = 31/229 (13%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEY-RFECLSDGLC 79
+ C F+C+ G CI L WKCD DC D SDE C Y +F C +G C
Sbjct: 1323 KVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRC-ENGHC 1381
Query: 80 IPRSWRCDATADCPDGSDEHQCE----VEACGPEEFTC-----RGKPGECVPLTWMCDDN 130
IP W+CD DC D SDE C + P TC R G CV TW+CD
Sbjct: 1382 IPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGY 1441
Query: 131 PDCSDGSDEKAC----NET----------CRSDEFTCGNGKCIQMRWVXXXXXXX-XXXX 175
DC+DGSDE+AC N T C EF C K W
Sbjct: 1442 RDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGR 1501
Query: 176 XEVKCPTP---TCQPQSHFSCTDGQ-CISAWWHCDGDVDCADGSDEVGC 220
E CPT TC + F C DG+ CI CDG +DC+D SDE C
Sbjct: 1502 DEANCPTHSTLTCMSRE-FQCEDGEACIVLSERCDGFLDCSDESDEKAC 1549
Score = 105 bits (253), Expect = 4e-22
Identities = 57/147 (38%), Positives = 73/147 (49%), Gaps = 15/147 (10%)
Query: 11 HIYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED--PTVCTATKMV--- 65
HI F TC + +RC +G C+ +W CD +DC+D SDE+ P + T
Sbjct: 1407 HILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLANVTAASTPT 1466
Query: 66 ----CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA---CGPEEFTCRGKPG 118
C + FEC CIP RCD DC DG DE C + C EF C + G
Sbjct: 1467 QLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQC--EDG 1524
Query: 119 E-CVPLTWMCDDNPDCSDGSDEKACNE 144
E C+ L+ CD DCSD SDEKAC++
Sbjct: 1525 EACIVLSERCDGFLDCSDESDEKACSD 1551
Score = 64.1 bits (149), Expect = 2e-09
Identities = 34/84 (40%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 23 CTSSEFRCKTGR-CIPLSWK-CDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
C EF C + CIP +WK CD +DC D DE T + + C F+C CI
Sbjct: 1471 CDRFEFECHQPKTCIP-NWKRCDGHQDCQDGRDE-ANCPTHSTLTCMSREFQCEDGEACI 1528
Query: 81 PRSWRCDATADCPDGSDEHQCEVE 104
S RCD DC D SDE C E
Sbjct: 1529 VLSERCDGFLDCSDESDEKACSDE 1552
>AC073319-1|AAX93075.1| 585|Homo sapiens unknown protein.
Length = 585
Score = 190 bits (462), Expect = 2e-47
Identities = 119/378 (31%), Positives = 187/378 (49%), Gaps = 30/378 (7%)
Query: 385 IDNRTCEDIDECADPGSCSQICINEKG--TFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
+ + CE +D PG CS IC+ T C C TG+ R+ CK + L +
Sbjct: 132 VRSHACE-VDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRS-CKRPKNELFLFY 189
Query: 443 ARKHD--IRKISLDHH---EMVAIVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDE 497
+ +R + L+ E + + + + ALD+ T I+++D I + ID
Sbjct: 190 GKGRPGIVRGMDLNTKIADEYMIPIENLVNPRALDFHAETNYIYFADTTSFLIGRQKID- 248
Query: 498 GTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNH-IELSDLQ--GNMRKILIRDRLEE 554
GT+R ++ + L +G+AVDW+ N+LYWT+ GH I ++ L+ RK L+ +
Sbjct: 249 GTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSH 308
Query: 555 PRAIALNPLEGWMFWTDWGQ------VPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVR 608
PR I ++P+ GWM+WTDW + V +IE+A MDG +R V+ + WPNGLTLD
Sbjct: 309 PRGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHT 368
Query: 609 QRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRAN 668
+YW DA + I +G+ R+ I++S L HPF ++ ++V+WTD+ ++++ +
Sbjct: 369 NTLYWCDAYYDHIEKVFLNGTHRK-IVYSGRELNHPFGLSHHGNYVFWTDYMNGSIFQLD 427
Query: 669 KFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPR 728
E H + +Y P R+ G N C NG CS LCL P R
Sbjct: 428 LITS---EVTLLRHERPPLFGLQIYDP-RKQQGDNMCRVNNGGCSTLCLAIP-----GGR 478
Query: 729 VSCACPNGLKLLPDDQMC 746
V CAC + L + C
Sbjct: 479 V-CACADNQLLDENGTTC 495
Score = 124 bits (298), Expect = 2e-27
Identities = 68/201 (33%), Positives = 103/201 (51%), Gaps = 14/201 (6%)
Query: 567 MFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNY 626
+F+TD+G V K+ER MDG +R+ I+ + P L LDLV + VYWVD ++ + +Y
Sbjct: 2 LFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALALDLVNKLVYWVDLYLDYVGVVDY 61
Query: 627 DGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQN 686
G R ++ +V RH + IT FED++Y T+ D + R N+FNG D+ ++ ++N
Sbjct: 62 QGKNRHTVIQGRQV-RHLYGITVFEDYLYATNSDNYNIVRINRFNGTDIHSLIK---IEN 117
Query: 687 PMVIHVYHPYRQPDGVNHCAAVN-----GHCSHLCLPAPRFGPNSPRVSCACPNGLKLLP 741
I +Y QP +H V+ G CSH+CL + + +C C G L
Sbjct: 118 AWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYKTR----TCRCRTGFNLGS 173
Query: 742 DDQMCVEDSKYHFLPFYNNFR 762
D + C FL FY R
Sbjct: 174 DGRSCKRPKNELFL-FYGKGR 193
Score = 78.2 bits (184), Expect = 1e-13
Identities = 33/76 (43%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C + EFRCK CI WKCD + DC D SDED C C + +F+C + CIP+
Sbjct: 507 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNC--FNHSCPDDQFKC-QNNRCIPK 563
Query: 83 SWRCDATADCPDGSDE 98
W CD DC DE
Sbjct: 564 RWLCDGANDCGSNEDE 579
Score = 74.5 bits (175), Expect = 1e-12
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 14/108 (12%)
Query: 48 CSDSS--DEDPTVCT-----ATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQ 100
C+D+ DE+ T CT A +C+ F C + CI W+CD DC DGSDE
Sbjct: 482 CADNQLLDENGTTCTFNPGEALPHICKAGEFRC-KNRHCIQARWKCDGDDDCLDGSDEDS 540
Query: 101 --CEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
C +C ++F C+ C+P W+CD DC GS+E N+TC
Sbjct: 541 VNCFNHSCPDDQFKCQNN--RCIPKRWLCDGANDC--GSNEDESNQTC 584
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--YNCTRQKTICDKRTEFDCGGGMCIPL 330
C+ +F+CK+ CI C+G DC DGSDE NC D +F C CIP
Sbjct: 507 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDD---QFKCQNNRCIPK 563
Query: 331 SKVCDKHVDCPNFEDEPRDRC 351
+CD DC + EDE C
Sbjct: 564 RWLCDGANDCGSNEDESNQTC 584
Score = 61.3 bits (142), Expect = 1e-08
Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 5/62 (8%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA--C-NETCRSDEFTCGNGKCIQMR 162
C EF C+ + C+ W CD + DC DGSDE + C N +C D+F C N +CI R
Sbjct: 507 CKAGEFRCKNR--HCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIPKR 564
Query: 163 WV 164
W+
Sbjct: 565 WL 566
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTP 183
+ D+N + +A C++ EF C N CIQ RW E V C
Sbjct: 487 LLDENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNH 546
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE 217
+C P F C + +CI W CDG DC DE
Sbjct: 547 SC-PDDQFKCQNNRCIPKRWLCDGANDCGSNEDE 579
Score = 52.0 bits (119), Expect = 8e-06
Identities = 35/104 (33%), Positives = 44/104 (42%), Gaps = 8/104 (7%)
Query: 211 CADGS--DEVG--CVSTPKVRSP--CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEAL 264
CAD DE G C P P C + EF C +R C+ W E
Sbjct: 482 CADNQLLDENGTTCTFNPGEALPHICKAGEFRCKNR-HCIQARWKCDGDDDCLDGSDEDS 540
Query: 265 ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
C N +C DQF+C+++ CIP C+G DC DE N T
Sbjct: 541 VNCF-NHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQT 583
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDE--VGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
F C + CI A W CDGD DC DGSDE V C + C +F+C + C+ + W
Sbjct: 512 FRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFN-----HSCPDDQFKCQNN-RCIPKRW 565
Query: 249 VXXXXXXXXXXXXEALELC 267
+ E+ + C
Sbjct: 566 LCDGANDCGSNEDESNQTC 584
Score = 49.6 bits (113), Expect = 4e-05
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCT 60
+ +C +F+C+ RCIP W CD DC + DE CT
Sbjct: 545 NHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCT 585
Score = 45.6 bits (103), Expect = 7e-04
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 346 EPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPG-SCS 403
+PR + G+N C NNGGCS C+ P G C C L +N T C +PG +
Sbjct: 450 DPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGT-----TCTFNPGEALP 504
Query: 404 QICINEKGTFKCE 416
IC + G F+C+
Sbjct: 505 HIC--KAGEFRCK 515
Score = 37.1 bits (82), Expect = 0.23
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 480 IFWSDV-NDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
+F++D N K+ + +D G RT +I + LA+D V +YW D +++ + D
Sbjct: 2 LFFTDYGNVAKVERCDMD-GMNRTRIIDSKTEQPAALALDLVNKLVYWVDLYLDYVGVVD 60
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKW 598
QG R +I+ R + + E +++ T+ + +G+ +++ + W
Sbjct: 61 YQGKNRHTVIQGR-QVRHLYGITVFEDYLYATNSDNYNIVRINRFNGTDIHSLIKIENAW 119
Score = 35.9 bits (79), Expect = 0.54
Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 268 RGNVTCRLDQFQCKDHS-CIPGALYC----NGVKDCPDGSDEYNCTRQKTICDKRTEFDC 322
+G+ CR++ C IPG C N + D + +N K EF C
Sbjct: 455 QGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGTTCTFNPGEALPHICKAGEFRC 514
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGC-SQRCVDTPIGYYCD 377
CI CD DC + DE C + C + C + RC+ P + CD
Sbjct: 515 KNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCI--PKRWLCD 568
>S73145-1|AAB30825.1| 268|Homo sapiens calcium sensor protein
protein.
Length = 268
Score = 178 bits (433), Expect = 7e-44
Identities = 96/227 (42%), Positives = 132/227 (58%), Gaps = 18/227 (7%)
Query: 513 DGLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDW 572
DG+AVDWV H+YW+D + IE++ L G RK LI L++P AIA+NP G MFWTDW
Sbjct: 7 DGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDW 66
Query: 573 GQVPKIERAGMDGSHRSTIVSYDVKWPNGLTLD-LVRQRVYWVDAKMNTISSCNYDGSGR 631
G+ PKIE A M+G R+ +V D+ WP GL++D L R+YW D K + I + YDG+ R
Sbjct: 67 GKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDR 126
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKF-NGKDVEAITSTHTLQNPMVI 690
R+I + E + +P+S+ FED +YW +K V++ NKF GK + + L +
Sbjct: 127 RVI--AKEAM-NPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQ---V 180
Query: 691 HVYHPYRQPDGV-NHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNG 736
++H R V N C + CSHLCL P SCACP G
Sbjct: 181 RIFHQLRYNKSVPNLCKQI---CSHLCLLRP------GGYSCACPQG 218
Score = 64.5 bits (150), Expect = 1e-09
Identities = 47/165 (28%), Positives = 83/165 (50%), Gaps = 9/165 (5%)
Query: 470 ALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDT 529
A+D+V R I+WSDV +++I A +D G R +I L +AV+ ++WTD
Sbjct: 10 AVDWVGRH--IYWSDVKNKRIEVAKLD-GRYRKWLISTDLDQPAAIAVNPKLGLMFWTDW 66
Query: 530 GHN-HIELSDLQGNMRKILIRDRLEEPRAIALNPLEG-WMFWTDWGQVPKIERAGMDGSH 587
G IE + + G R IL+ + L P ++++ L ++W+D+ + IE DG+
Sbjct: 67 GKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKE-DVIETIKYDGTD 125
Query: 588 RSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRR 632
R I + N +LD+ ++YW+ + + N G G++
Sbjct: 126 RRVIAKEAM---NPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKK 167
Score = 49.6 bits (113), Expect = 4e-05
Identities = 31/136 (22%), Positives = 65/136 (47%), Gaps = 6/136 (4%)
Query: 461 IVNDTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWV 520
I D A+ + G++FW+D E ++ G R +++ E L GL++D++
Sbjct: 42 ISTDLDQPAAIAVNPKLGLMFWTDWGKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYL 101
Query: 521 YN-HLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFW--TDWGQVPK 577
N +YW+D + IE G R+++ ++ + +L+ E ++W + G+V K
Sbjct: 102 NNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAM---NPYSLDIFEDQLYWISKEKGEVWK 158
Query: 578 IERAGMDGSHRSTIVS 593
+ G ++ +V+
Sbjct: 159 QNKFGQGKKEKTLVVN 174
Score = 45.2 bits (102), Expect = 9e-04
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 596 VKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFE--DW 653
V P+G+ +D V + +YW D K I DG R+ ++ ST+ L P +I
Sbjct: 3 VMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLI-STD-LDQPAAIAVNPKLGL 60
Query: 654 VYWTDWDKTAVYRANKFNGKD 674
++WTDW K + NG+D
Sbjct: 61 MFWTDWGKEPKIESAWMNGED 81
>AC117947-1|AAX88968.1| 346|Homo sapiens unknown protein.
Length = 346
Score = 176 bits (428), Expect = 3e-43
Identities = 98/277 (35%), Positives = 157/277 (56%), Gaps = 16/277 (5%)
Query: 480 IFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSDL 539
I+W+D+ KI +A D+ T + +I L +G+AVDW+ ++YWTD G N IE++ L
Sbjct: 4 IYWTDMGFNKISRAKRDQ-TWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARL 62
Query: 540 QGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVKWP 599
G+ R ++I L++PR+IA++P +G +FWT+WGQ+P I +A +DGS + +VS + WP
Sbjct: 63 NGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWP 122
Query: 600 NGLTLDLVRQRVYWVDAKMNTISSCNYD-GSGRRLILHSTEVLRHPFSITTFEDWVYWTD 658
NG+++D ++YW DA+ + I + + G R ++L + V FS+ F ++YW+D
Sbjct: 123 NGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNV--DMFSVAVFGAYIYWSD 180
Query: 659 --WDKTAVYRANKFNGKDVEAITSTHTL-QNPMVIHVYHPYRQPDGVNHCAAVNGHCSHL 715
+V R +K + E IT L N + +++ R+ G N CA NG C L
Sbjct: 181 RAHANGSVRRGHKNDA--TETITMRTGLGVNLKEVKIFNRVRE-KGTNVCARDNGGCKQL 237
Query: 716 CLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
CL + NS R +CAC +G L D C+ Y
Sbjct: 238 CL----YRGNSRR-TCACAHGY-LAEDGVTCLRHEGY 268
Score = 36.3 bits (80), Expect = 0.41
Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 448 IRKISLDHHEMVAIVN---DTKSATALDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVV 504
I K LD E V +V+ + ++DY ++W D +KI + ++ G R +V
Sbjct: 101 IGKARLDGSEKVVLVSMGIAWPNGISIDY--EENKLYWCDARTDKIERIDLETGGNREMV 158
Query: 505 IGEQLITSDGLAVDWVYNHLYWTDTGH 531
+ + +AV Y +YW+D H
Sbjct: 159 LSGSNVDMFSVAVFGAY--IYWSDRAH 183
Score = 33.9 bits (74), Expect = 2.2
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Query: 352 GENECEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNRTC 390
G N C ++NGGC Q C+ C C GY D TC
Sbjct: 223 GTNVCARDNGGCKQLCLYRGNSRRTCACAHGYLAEDGVTC 262
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 161 bits (392), Expect = 6e-39
Identities = 76/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%)
Query: 471 LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG 530
+DY R M++W+DV I +A ++ G + ++ LI+ +GLA+D + +YWTD+
Sbjct: 1148 IDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSV 1207
Query: 531 HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRS 589
+ IE + L G+ RK+L L PRAIA++P+ G ++WTDW + PKIE + +DG +R
Sbjct: 1208 LDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRR 1267
Query: 590 TIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITT 649
+++ D+ PNGLT D + + W DA + DG+GRR+I ++ L++PFSI +
Sbjct: 1268 ILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVS 1324
Query: 650 FEDWVYWTDWDKTAVYRANKFNGK 673
+ D Y TDW + V NK +G+
Sbjct: 1325 YADHFYHTDWRRDGVVSVNKHSGQ 1348
Score = 52.4 bits (120), Expect = 6e-06
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 346 EPRDRCGENECEKNNGGC--SQRC-VDTPIGYYCDCEKGYKLIDNRTCEDIDECADP-GS 401
E D N C + C + RC T + Y C+C GY+ D R C D +ECA
Sbjct: 754 EDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQG-DGRNCVDENECATGFHR 812
Query: 402 C--SQICINEKGTFKCECHTGY 421
C + +CIN G+++CEC +GY
Sbjct: 813 CGPNSVCINLPGSYRCECRSGY 834
Score = 52.4 bits (120), Expect = 6e-06
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 18/130 (13%)
Query: 327 CIPLSKVCDKHVDCPN-FEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYK 383
C P + V D +C + ++ + R+ ENEC C C++ P Y C+C GY+
Sbjct: 777 CHPGTGV-DYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYE 835
Query: 384 LIDNR-TCEDIDECADP---GS--CSQI----CINEKG-TFKCECHTGYARDPR---DRT 429
D+R TC I A+P GS C+ C++ G TF C C GYA D D
Sbjct: 836 FADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVD 895
Query: 430 RCKATEGHPS 439
C HP+
Sbjct: 896 ECSENRCHPA 905
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 354 NECEKNNGGCSQ----RCVDTPIGYY-CDCEKGYKLIDNRTCEDIDECADPGSC--SQIC 406
N CE + C+ RCV + C C GY D C D+DEC++ C + C
Sbjct: 851 NPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAG-DGHQCTDVDECSE-NRCHPAATC 908
Query: 407 INEKGTFKCECHTGYARD 424
N G+F C C GY D
Sbjct: 909 YNTPGSFSCRCQPGYYGD 926
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 161 bits (392), Expect = 6e-39
Identities = 76/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%)
Query: 471 LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG 530
+DY R M++W+DV I +A ++ G + ++ LI+ +GLA+D + +YWTD+
Sbjct: 741 IDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSV 800
Query: 531 HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRS 589
+ IE + L G+ RK+L L PRAIA++P+ G ++WTDW + PKIE + +DG +R
Sbjct: 801 LDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRR 860
Query: 590 TIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITT 649
+++ D+ PNGLT D + + W DA + DG+GRR+I ++ L++PFSI +
Sbjct: 861 ILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVS 917
Query: 650 FEDWVYWTDWDKTAVYRANKFNGK 673
+ D Y TDW + V NK +G+
Sbjct: 918 YADHFYHTDWRRDGVVSVNKHSGQ 941
Score = 50.0 bits (114), Expect = 3e-05
Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 7/82 (8%)
Query: 346 EPRDRCGENECEKNNGGC--SQRC-VDTPIGYYCDCEKGYKLIDNRTCEDIDECADP-GS 401
E D N C + C + RC T + Y C+C GY+ D R C D +ECA
Sbjct: 347 EDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQG-DGRNCVDENECATGFHR 405
Query: 402 C--SQICINEKGTFKCECHTGY 421
C + +CIN G+++CEC + Y
Sbjct: 406 CGPNSVCINLPGSYRCECRSAY 427
Score = 50.0 bits (114), Expect = 3e-05
Identities = 41/130 (31%), Positives = 58/130 (44%), Gaps = 18/130 (13%)
Query: 327 CIPLSKVCDKHVDCPN-FEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYK 383
C P + V D +C + ++ + R+ ENEC C C++ P Y C+C Y+
Sbjct: 370 CHPGTGV-DYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSAYE 428
Query: 384 LIDNR-TCEDIDECADP---GS--CSQI----CINEKG-TFKCECHTGYARDPR---DRT 429
D+R TC I A+P GS C+ C++ G TF C C GYA D D
Sbjct: 429 FADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVD 488
Query: 430 RCKATEGHPS 439
C HP+
Sbjct: 489 ECSENRCHPA 498
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 354 NECEKNNGGCSQ----RCVDTPIGYY-CDCEKGYKLIDNRTCEDIDECADPGSC--SQIC 406
N CE + C+ RCV + C C GY D C D+DEC++ C + C
Sbjct: 444 NPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAG-DGHQCTDVDECSE-NRCHPAATC 501
Query: 407 INEKGTFKCECHTGYARD 424
N G+F C C GY D
Sbjct: 502 YNTPGSFSCRCQPGYYGD 519
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 161 bits (392), Expect = 6e-39
Identities = 76/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%)
Query: 471 LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG 530
+DY R M++W+DV I +A ++ G + ++ LI+ +GLA+D + +YWTD+
Sbjct: 1147 IDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSV 1206
Query: 531 HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRS 589
+ IE + L G+ RK+L L PRAIA++P+ G ++WTDW + PKIE + +DG +R
Sbjct: 1207 LDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRR 1266
Query: 590 TIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITT 649
+++ D+ PNGLT D + + W DA + DG+GRR+I ++ L++PFSI +
Sbjct: 1267 ILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVS 1323
Query: 650 FEDWVYWTDWDKTAVYRANKFNGK 673
+ D Y TDW + V NK +G+
Sbjct: 1324 YADHFYHTDWRRDGVVSVNKHSGQ 1347
Score = 52.4 bits (120), Expect = 6e-06
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 346 EPRDRCGENECEKNNGGC--SQRC-VDTPIGYYCDCEKGYKLIDNRTCEDIDECADP-GS 401
E D N C + C + RC T + Y C+C GY+ D R C D +ECA
Sbjct: 753 EDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQG-DGRNCVDENECATGFHR 811
Query: 402 C--SQICINEKGTFKCECHTGY 421
C + +CIN G+++CEC +GY
Sbjct: 812 CGPNSVCINLPGSYRCECRSGY 833
Score = 52.4 bits (120), Expect = 6e-06
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 18/130 (13%)
Query: 327 CIPLSKVCDKHVDCPN-FEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYK 383
C P + V D +C + ++ + R+ ENEC C C++ P Y C+C GY+
Sbjct: 776 CHPGTGV-DYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYE 834
Query: 384 LIDNR-TCEDIDECADP---GS--CSQI----CINEKG-TFKCECHTGYARDPR---DRT 429
D+R TC I A+P GS C+ C++ G TF C C GYA D D
Sbjct: 835 FADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVD 894
Query: 430 RCKATEGHPS 439
C HP+
Sbjct: 895 ECSENRCHPA 904
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 354 NECEKNNGGCSQ----RCVDTPIGYY-CDCEKGYKLIDNRTCEDIDECADPGSC--SQIC 406
N CE + C+ RCV + C C GY D C D+DEC++ C + C
Sbjct: 850 NPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAG-DGHQCTDVDECSE-NRCHPAATC 907
Query: 407 INEKGTFKCECHTGYARD 424
N G+F C C GY D
Sbjct: 908 YNTPGSFSCRCQPGYYGD 925
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 161 bits (392), Expect = 6e-39
Identities = 76/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%)
Query: 471 LDYVFRTGMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTG 530
+DY R M++W+DV I +A ++ G + ++ LI+ +GLA+D + +YWTD+
Sbjct: 1148 IDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSV 1207
Query: 531 HNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG-QVPKIERAGMDGSHRS 589
+ IE + L G+ RK+L L PRAIA++P+ G ++WTDW + PKIE + +DG +R
Sbjct: 1208 LDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRR 1267
Query: 590 TIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITT 649
+++ D+ PNGLT D + + W DA + DG+GRR+I ++ L++PFSI +
Sbjct: 1268 ILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVS 1324
Query: 650 FEDWVYWTDWDKTAVYRANKFNGK 673
+ D Y TDW + V NK +G+
Sbjct: 1325 YADHFYHTDWRRDGVVSVNKHSGQ 1348
Score = 52.4 bits (120), Expect = 6e-06
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 346 EPRDRCGENECEKNNGGC--SQRC-VDTPIGYYCDCEKGYKLIDNRTCEDIDECADP-GS 401
E D N C + C + RC T + Y C+C GY+ D R C D +ECA
Sbjct: 754 EDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQG-DGRNCVDENECATGFHR 812
Query: 402 C--SQICINEKGTFKCECHTGY 421
C + +CIN G+++CEC +GY
Sbjct: 813 CGPNSVCINLPGSYRCECRSGY 834
Score = 52.4 bits (120), Expect = 6e-06
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 18/130 (13%)
Query: 327 CIPLSKVCDKHVDCPN-FEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYK 383
C P + V D +C + ++ + R+ ENEC C C++ P Y C+C GY+
Sbjct: 777 CHPGTGV-DYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYE 835
Query: 384 LIDNR-TCEDIDECADP---GS--CSQI----CINEKG-TFKCECHTGYARDPR---DRT 429
D+R TC I A+P GS C+ C++ G TF C C GYA D D
Sbjct: 836 FADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVD 895
Query: 430 RCKATEGHPS 439
C HP+
Sbjct: 896 ECSENRCHPA 905
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 354 NECEKNNGGCSQ----RCVDTPIGYY-CDCEKGYKLIDNRTCEDIDECADPGSC--SQIC 406
N CE + C+ RCV + C C GY D C D+DEC++ C + C
Sbjct: 851 NPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAG-DGHQCTDVDECSE-NRCHPAATC 908
Query: 407 INEKGTFKCECHTGYARD 424
N G+F C C GY D
Sbjct: 909 YNTPGSFSCRCQPGYYGD 926
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 325 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 383
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 384 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 443
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 444 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 500
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 501 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 558
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 559 ATP--GSR----TCRCPD 570
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 316 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 374
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 375 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 434
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 435 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 491
Query: 692 VY 693
Y
Sbjct: 492 SY 493
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 3 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 61
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 62 NNHPGTFRCECVEGY 76
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 13 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 69
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 70 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 123
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 124 LPGFSG-DGQACQDVDEC-QPSRCHPDAFCYNTPGSFTCQCKPGYQGD 169
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 542 GHNYCSVNNGGCTHLCLATPGSRTCRC 568
>BC045606-1|AAH45606.1| 1114|Homo sapiens NID1 protein protein.
Length = 1114
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 858 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 916
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 917 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 976
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 977 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1033
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1034 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1091
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1092 ATP--GSR----TCRCPD 1103
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 849 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 907
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 908 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 967
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 968 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1024
Query: 692 VY 693
Y
Sbjct: 1025 SY 1026
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1075 GHNYCSVNNGGCTHLCLATPGSRTCRC 1101
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 991 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 1049
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 1050 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 1109
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 1110 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1166
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1167 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1224
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1225 ATP--GSR----TCRCPD 1236
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 982 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 1040
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 1041 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 1100
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 1101 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1157
Query: 692 VY 693
Y
Sbjct: 1158 SY 1159
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 669 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 727
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 728 NNHPGTFRCECVEGY 742
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 735
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 736 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 790 LPGFSG-DGQACQDVDEC-QPSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1208 GHNYCSVNNGGCTHLCLATPGSRTCRC 1234
>AL139161-1|CAI23421.1| 1114|Homo sapiens nidogen 1 protein.
Length = 1114
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 858 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 916
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 917 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 976
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 977 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1033
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1034 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1091
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1092 ATP--GSR----TCRCPD 1103
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 849 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 907
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 908 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 967
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 968 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1024
Query: 692 VY 693
Y
Sbjct: 1025 SY 1026
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1075 GHNYCSVNNGGCTHLCLATPGSRTCRC 1101
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 991 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 1049
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 1050 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 1109
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 1110 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1166
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1167 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1224
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1225 ATP--GSR----TCRCPD 1236
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 982 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 1040
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 1041 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 1100
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 1101 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1157
Query: 692 VY 693
Y
Sbjct: 1158 SY 1159
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 669 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 727
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 728 NNHPGTFRCECVEGY 742
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 735
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 736 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 790 LPGFSG-DGQACQDVDEC-QPSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1208 GHNYCSVNNGGCTHLCLATPGSRTCRC 1234
>AL122018-1|CAI22680.1| 1114|Homo sapiens nidogen 1 protein.
Length = 1114
Score = 156 bits (379), Expect = 2e-37
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 858 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 916
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 917 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 976
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 977 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1033
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1034 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1091
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1092 ATP--GSR----TCRCPD 1103
Score = 82.6 bits (195), Expect = 5e-15
Identities = 54/182 (29%), Positives = 79/182 (43%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 849 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 907
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 908 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 967
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 968 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1024
Query: 692 VY 693
Y
Sbjct: 1025 SY 1026
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1075 GHNYCSVNNGGCTHLCLATPGSRTCRC 1101
>BC139736-1|AAI39737.1| 224|Homo sapiens LRP5L protein protein.
Length = 224
Score = 155 bits (375), Expect = 7e-37
Identities = 73/192 (38%), Positives = 113/192 (58%), Gaps = 3/192 (1%)
Query: 478 GMIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELS 537
G ++W+D I +A +D G+ +I ++ D +AV+WV LYWT TG HIE++
Sbjct: 3 GHVYWTDDEVWAIRRAYLD-GSGAQTLINTKINDPDDIAVNWVARSLYWTHTGTEHIEVT 61
Query: 538 DLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQVPKIERAGMDGSHRSTIVSYDVK 597
L KIL+ + ++EPRAIAL+P G +W DWG+ P+I+RA +D +V+ +
Sbjct: 62 CLNSTSHKILVSEDMDEPRAIALHPEMGLTYWIDWGENPEIKRANLDRQELRVLVNASLG 121
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
WPNGL LDL ++YW DAK + I + + D + R+ +L + L H F T D++YWT
Sbjct: 122 WPNGLALDLQEGKLYWGDAKTDKIEAISVDETKRQTLL--KDKLPHIFRFTLLGDFIYWT 179
Query: 658 DWDKTAVYRANK 669
W ++ R +K
Sbjct: 180 AWQHHSIKRVHK 191
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 153 bits (372), Expect = 2e-36
Identities = 85/258 (32%), Positives = 139/258 (53%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 990 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 1048
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 1049 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 1108
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGL D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 1109 LPNGLHFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1165
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1166 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1223
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1224 ATP--GSR----TCRCPD 1235
Score = 81.8 bits (193), Expect = 8e-15
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 981 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 1039
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 1040 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 1099
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + F + W D RA N + LQ P +
Sbjct: 1100 RILVQDDLGLPNGLHFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1156
Query: 692 VY 693
Y
Sbjct: 1157 SY 1158
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 668 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 726
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 727 NNHPGTFRCECVEGY 741
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 678 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 734
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 735 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 788
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 789 LPGFSG-DGQACQDVDEC-QPSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1207 GHNYCSVNNGGCTHLCLATPGSRTCRC 1233
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 153 bits (372), Expect = 2e-36
Identities = 85/258 (32%), Positives = 139/258 (53%), Gaps = 13/258 (5%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G + T +I + L + +G+AVD + +++WTD+ + IE++
Sbjct: 991 MVYWTDITEPSIGRASL-HGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAK 1049
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 1050 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 1109
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGL D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 1110 LPNGLHFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1166
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1167 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1224
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1225 ATP--GSR----TCRCPD 1236
Score = 81.8 bits (193), Expect = 8e-15
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 6/182 (3%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR L P IA++ L +FWTD
Sbjct: 982 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTD-S 1040
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 1041 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 1100
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + F + W D RA N + LQ P +
Sbjct: 1101 RILVQDDLGLPNGLHFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1157
Query: 692 VY 693
Y
Sbjct: 1158 SY 1159
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 669 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 727
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 728 NNHPGTFRCECVEGY 742
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 735
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 736 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 790 LPGFSG-DGQACQDVDEC-QPSRCHPDAFCYNTPGSFTCQCKPGYQGD 835
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1208 GHNYCSVNNGGCTHLCLATPGSRTCRC 1234
>AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein
protein.
Length = 363
Score = 151 bits (366), Expect = 9e-36
Identities = 77/216 (35%), Positives = 99/216 (45%), Gaps = 15/216 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD-GLCIP 81
C +EF+C+ G+CI W CD +C D SDE C + + C+ F C CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLS--VTCKSGDFSCGGRVNRCIP 84
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ WRCD DC +GSDE C + C +EF C G+C+ ++CD + DC DGSDE +
Sbjct: 85 QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCH--DGKCISRQFVCDSDRDCLDGSDEAS 142
Query: 142 CNE-TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCP-----TPTCQPQS--HF 191
C C F C + CI W E +C P S F
Sbjct: 143 CPVLICGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEF 202
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVR 227
C G+CI + W CDG DC D SDE C VR
Sbjct: 203 HCLSGECIHSSWRCDGGPDCKDKSDEENCGGRSTVR 238
Score = 134 bits (325), Expect = 8e-31
Identities = 77/222 (34%), Positives = 103/222 (46%), Gaps = 21/222 (9%)
Query: 104 EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE--KAC-NETCRSDEFTCGN--GKC 158
+ C EF C+ G+C+ W+CD + +C DGSDE + C + TC+S +F+CG +C
Sbjct: 25 DRCERNEFQCQD--GKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRC 82
Query: 159 IQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEV 218
I W E CP TC Q F C DG+CIS + CD D DC DGSDE
Sbjct: 83 IPQFWRCDGQVDCDNGSDEQGCPPKTCS-QDEFRCHDGKCISRQFVCDSDRDCLDGSDEA 141
Query: 219 GCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRG-------NV 271
C P + C F+CN TC+ + W E + CRG +
Sbjct: 142 SC---PVL--ICGPASFQCNSS-TCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSS 195
Query: 272 TCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI 313
C +F C CI + C+G DC D SDE NC + T+
Sbjct: 196 PCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCGGRSTV 237
Score = 111 bits (267), Expect = 9e-24
Identities = 78/224 (34%), Positives = 97/224 (43%), Gaps = 25/224 (11%)
Query: 141 ACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK--CPTPTCQPQSHFSCTD--G 196
A + C +EF C +GKCI +WV E + C + TC+ FSC
Sbjct: 22 AVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCK-SGDFSCGGRVN 80
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+CI +W CDG VDC +GSDE GC PK C EF C+D C+ R +V
Sbjct: 81 RCIPQFWRCDGQVDCDNGSDEQGC--PPKT---CSQDEFRCHDG-KCISRQFVCDSDRDC 134
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE--------YNCT 308
EA C + C FQC +CIP C+ DC DGSDE Y
Sbjct: 135 LDGSDEA--SC-PVLICGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQ 191
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCG 352
+ C EF C G CI S CD DC + DE + CG
Sbjct: 192 GDSSPC-SAFEFHCLSGECIHSSWRCDGGPDCKDKSDE--ENCG 232
Score = 108 bits (259), Expect = 8e-23
Identities = 52/132 (39%), Positives = 69/132 (52%), Gaps = 17/132 (12%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC+ EFRC G+CI + CD+++DC D SDE + ++C F+C + CI
Sbjct: 107 KTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE----ASCPVLICGPASFQC-NSSTCI 161
Query: 81 PRSWRCDATADCPDGSDE----------HQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
P+ W CD DC DGSDE Q + C EF C GEC+ +W CD
Sbjct: 162 PQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS--GECIHSSWRCDGG 219
Query: 131 PDCSDGSDEKAC 142
PDC D SDE+ C
Sbjct: 220 PDCKDKSDEENC 231
Score = 88.2 bits (209), Expect = 1e-16
Identities = 45/112 (40%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV------CQEYRFECLSD 76
C + F+C + CIP W CDN+ DC D SDE P C + C + F CLS
Sbjct: 148 CGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLS- 206
Query: 77 GLCIPRSWRCDATADCPDGSDEHQC----EVEACGPEEFTCRGKPGECVPLT 124
G CI SWRCD DC D SDE C V PE +G+P P T
Sbjct: 207 GECIHSSWRCDGGPDCKDKSDEENCGGRSTVRFSWPERTLRKGRPHPAAPGT 258
Score = 72.9 bits (171), Expect = 4e-12
Identities = 39/99 (39%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGG--GMCIPL 330
C ++FQC+D CI C+G +C DGSDE T C K +F CGG CIP
Sbjct: 27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTC-KSGDFSCGGRVNRCIPQ 85
Query: 331 SKVCDKHVDCPNFEDE---PRDRCGENECEKNNGGCSQR 366
CD VDC N DE P C ++E ++G C R
Sbjct: 86 FWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISR 124
Score = 50.4 bits (115), Expect = 2e-05
Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 12 IYFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED 55
+Y F +S C++ EF C +G CI SW+CD DC D SDE+
Sbjct: 187 LYVFQ-GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEE 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 316 KRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
+R EF C G CI VCD +C + DE ++ C C+ + C R V+ I +
Sbjct: 28 ERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGR-VNRCIPQF 86
Query: 376 CDCEKGYKLIDNRTCEDIDECADPGSCSQ 404
C+ G DN + E + P +CSQ
Sbjct: 87 WRCD-GQVDCDNGSDE---QGCPPKTCSQ 111
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 150 bits (364), Expect = 2e-35
Identities = 85/258 (32%), Positives = 136/258 (52%), Gaps = 18/258 (6%)
Query: 479 MIFWSDVNDEKIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIELSD 538
M++W+D+ + I +A + G T+ I +G+AVD + +++WTD+ + IE++
Sbjct: 990 MVYWTDITEPSIGRASLHGGEPTTI------IRQEGIAVDHLGRNIFWTDSNLDRIEVAK 1043
Query: 539 LQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ-VPKIERAGMDGSHRSTIVSYDVK 597
L G R++L L PR I + + G ++WTDW + PKIE + MDG++R +V D+
Sbjct: 1044 LDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLG 1103
Query: 598 WPNGLTLDLVRQRVYWVDAKMNTISSCNYDGSGRRLILHSTEVLRHPFSITTFEDWVYWT 657
PNGLT D ++ WVDA N N RR L E L++PF++T++ +Y+T
Sbjct: 1104 LPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKAL---EGLQYPFAVTSYGKNLYFT 1160
Query: 658 DWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCL 717
DW +V + K+ +A H Q + + P G N+C+ NG C+HLCL
Sbjct: 1161 DWKMNSVVALDLAISKETDAF-QPHK-QTRLYGITTALSQCPQGHNYCSVNNGGCTHLCL 1218
Query: 718 PAPRFGPNSPRVSCACPN 735
P G +C CP+
Sbjct: 1219 ATP--GSR----TCRCPD 1230
Score = 72.1 bits (169), Expect = 7e-12
Identities = 52/182 (28%), Positives = 77/182 (42%), Gaps = 11/182 (6%)
Query: 514 GLAVDWVYNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWG 573
GLA D V +YWTD I + L G +IR IA++ L +FWTD
Sbjct: 981 GLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQ-----EGIAVDHLGRNIFWTD-S 1034
Query: 574 QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNT--ISSCNYDGSGR 631
+ +IE A +DG+ R + D+ P G+ D VR +YW D + I + DG+ R
Sbjct: 1035 NLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNR 1094
Query: 632 RLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQNPMVIH 691
R+++ L + + F + W D RA N + LQ P +
Sbjct: 1095 RILVQDDLGLPNGLTFDAFSSQLCWVD---AGTNRAECLNPSQPSRRKALEGLQYPFAVT 1151
Query: 692 VY 693
Y
Sbjct: 1152 SY 1153
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/75 (40%), Positives = 38/75 (50%), Gaps = 7/75 (9%)
Query: 353 ENECEKNNGGCSQRCVDTP---IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ--IC 406
+N C GC P + C+C G++ D RTC DIDEC++ P C IC
Sbjct: 668 QNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRG-DGRTCYDIDECSEQPSVCGSHTIC 726
Query: 407 INEKGTFKCECHTGY 421
N GTF+CEC GY
Sbjct: 727 NNHPGTFRCECVEGY 741
Score = 51.2 bits (117), Expect = 1e-05
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 267 CRGNVTCR---LDQFQCKDHSCIPG-ALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFD 321
C N CR QF C+ G C + +C S++ + TIC+ F
Sbjct: 678 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDEC---SEQPSVCGSHTICNNHPGTFR 734
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR--CVDTP-IGYYCDC 378
C C+ + D+ + P + C E +N QR C+ T Y C C
Sbjct: 735 CE---CVEGYQFSDEGTCVAVVDQRPINYC---ETGLHNCDIPQRAQCIYTGGSSYTCSC 788
Query: 379 EKGYKLIDNRTCEDIDECADPGSC--SQICINEKGTFKCECHTGYARD 424
G+ D + C+D+DEC P C C N G+F C+C GY D
Sbjct: 789 LPGFSG-DGQACQDVDEC-HPSRCHPDAFCYNTPGSFTCQCKPGYQGD 834
Score = 35.1 bits (77), Expect = 0.94
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDC 378
G N C NNGGC+ C+ TP C C
Sbjct: 1202 GHNYCSVNNGGCTHLCLATPGSRTCRC 1228
>AL450467-1|CAH72452.1| 173|Homo sapiens very low density
lipoprotein receptor protein.
Length = 173
Score = 146 bits (353), Expect = 3e-34
Identities = 67/145 (46%), Positives = 82/145 (56%), Gaps = 10/145 (6%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C S+F+C GRCI L WKCD ++DC D SDE V K C E F C ++G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCV----KKTCAESDFVC-NNGQCVPS 87
Query: 83 SWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEK 140
W+CD DC DGSDE QC C P+EFTC G C+ ++C+ DCSDGSDE
Sbjct: 88 RWKCDGDPDCEDGSDESPEQCRNITCSPDEFTC--SSGRCISRNFVCNGQDDCSDGSDEL 145
Query: 141 AC-NETCRSDEFTCGNGKCIQMRWV 164
C TC + EF C CI + WV
Sbjct: 146 DCAPPTCGAHEFQCSTSSCIPISWV 170
Score = 135 bits (327), Expect = 5e-31
Identities = 62/150 (41%), Positives = 78/150 (52%), Gaps = 7/150 (4%)
Query: 60 TATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGE 119
T K C+ +F+C ++G CI W+CD DC DGSDE C + C +F C G+
Sbjct: 27 TGRKAKCEPSQFQC-TNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNN--GQ 83
Query: 120 CVPLTWMCDDNPDCSDGSDE--KAC-NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXX 176
CVP W CD +PDC DGSDE + C N TC DEFTC +G+CI +V
Sbjct: 84 CVPSRWKCDGDPDCEDGSDESPEQCRNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSD 143
Query: 177 EVKCPTPTCQPQSHFSCTDGQCISAWWHCD 206
E+ C PTC F C+ CI W CD
Sbjct: 144 ELDCAPPTCGAH-EFQCSTSSCIPISWVCD 172
Score = 125 bits (302), Expect = 5e-28
Identities = 64/151 (42%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 185 CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
C+P S F CT+G+CI+ W CDGD DC DGSDE C V+ C ++F CN+ CV
Sbjct: 33 CEP-SQFQCTNGRCITLLWKCDGDEDCVDGSDEKNC-----VKKTCAESDFVCNNG-QCV 85
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
W E+ E CR N+TC D+F C CI CNG DC DGSDE
Sbjct: 86 PSRWKCDGDPDCEDGSDESPEQCR-NITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDE 144
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCD 335
+C C EF C CIP+S VCD
Sbjct: 145 LDCA--PPTCGAH-EFQCSTSSCIPISWVCD 172
Score = 117 bits (281), Expect = 2e-25
Identities = 48/109 (44%), Positives = 61/109 (55%), Gaps = 5/109 (4%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
+TC S+F C G+C+P WKCD + DC D SDE P C + C F C S G CI
Sbjct: 70 KTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQC--RNITCSPDEFTC-SSGRCI 126
Query: 81 PRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDD 129
R++ C+ DC DGSDE C CG EF C C+P++W+CDD
Sbjct: 127 SRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQC--STSSCIPISWVCDD 173
Score = 76.6 bits (180), Expect = 3e-13
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
C QFQC + CI C+G +DC DGSDE NC + KT + ++F C G C+P
Sbjct: 33 CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVK-KTCAE--SDFVCNNGQCVPSRW 89
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC----DCEKGYKLID 386
CD DC + DE ++C C + CS RC+ + C DC G +D
Sbjct: 90 KCDGDPDCEDGSDESPEQCRNITCSPDEFTCSSGRCISR--NFVCNGQDDCSDGSDELD 146
>BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein.
Length = 296
Score = 140 bits (338), Expect = 2e-32
Identities = 80/226 (35%), Positives = 115/226 (50%), Gaps = 12/226 (5%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVND 487
A +I L ++ I T+ TA+D+ + + W V D
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGD 249
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 75.4 bits (177), Expect = 7e-13
Identities = 55/184 (29%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECAD 398
E D
Sbjct: 193 EPVD 196
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein.
Length = 296
Score = 140 bits (338), Expect = 2e-32
Identities = 80/226 (35%), Positives = 115/226 (50%), Gaps = 12/226 (5%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVND 487
A +I L ++ I T+ TA+D+ + + W V D
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGD 249
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 75.4 bits (177), Expect = 7e-13
Identities = 55/184 (29%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECAD 398
E D
Sbjct: 193 EPVD 196
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein.
Length = 292
Score = 140 bits (338), Expect = 2e-32
Identities = 80/226 (35%), Positives = 115/226 (50%), Gaps = 12/226 (5%)
Query: 272 TCRLDQFQCKDH-SCIPGALYCNGVKDCPDGSDEYN--CTRQKTICDKRTEFDC-GGGMC 327
TC QF C+D +CI C+G +DCPDGSDE C + K + E +C G +C
Sbjct: 26 TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELC 85
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-ID 386
+P+S++C+ DC + DE C E + + GC CV T G C C ++L D
Sbjct: 86 VPMSRLCNGVQDCMDGSDEG-PHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQAD 144
Query: 387 NRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKA----TEGHPSLLF 442
+TC+D DEC+ G+CSQ+C N G+F C C GY P +R+ CKA + P LL
Sbjct: 145 GKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRS-CKAKNEPVDRPPVLLI 203
Query: 443 ARKHDIRKISLDHHEMVAIV-NDTKSATALDYVFRTGMIFWSDVND 487
A +I L ++ I T+ TA+D+ + + W V D
Sbjct: 204 ANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGD 249
Score = 85.4 bits (202), Expect = 7e-16
Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 21 RTCTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATK-MVCQEYRFECLSDGL 78
+TC+ +F C+ CI W+CD E+DC D SDE P +C +K CQ CL L
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD--CSDG 136
C+P S C+ DC DGSDE E G + G CVP D P C+
Sbjct: 85 CVPMSRLCNGVQDCMDGSDEGPHCRELQG--NCSRLGCQHHCVPTL----DGPTCYCNSS 138
Query: 137 SDEKACNETCRSDEFTCGNGKCIQM 161
+A +TC+ + G C Q+
Sbjct: 139 FQLQADGKTCKDFDECSVYGTCSQL 163
Score = 75.4 bits (177), Expect = 7e-13
Identities = 55/184 (29%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVT--CRLDQF 278
+ PK SP +F C D+ITC+ + W EA E+C + C+ ++
Sbjct: 21 IDAPKTCSP---KQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEH 77
Query: 279 QC-KDHSCIPGALYCNGVKDCPDGSDE-YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C C+P + CNGV+DC DGSDE +C + C + C C+P
Sbjct: 78 NCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR---LGC-QHHCVPTLDGPTC 133
Query: 337 HVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDID 394
+ + C + +EC G CSQ C +T + C C +GY L DNR+C+ +
Sbjct: 134 YCNSSFQLQADGKTCKDFDECSV-YGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Query: 395 ECAD 398
E D
Sbjct: 193 EPVD 196
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 184 TCQPQSHFSCTDG-QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRIT 242
TC P+ F+C D CIS W CDG+ DC DGSDE + C E C
Sbjct: 26 TCSPKQ-FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 243 CV 244
CV
Sbjct: 85 CV 86
Score = 35.5 bits (78), Expect = 0.71
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 6/80 (7%)
Query: 144 ETCRSDEFTCGNG-KCIQMRWVXXXXXXXXXXXXEVK--CP---TPTCQPQSHFSCTDGQ 197
+TC +F C + CI W E CP CQP H
Sbjct: 25 KTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTEL 84
Query: 198 CISAWWHCDGDVDCADGSDE 217
C+ C+G DC DGSDE
Sbjct: 85 CVPMSRLCNGVQDCMDGSDE 104
>AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.
Length = 1322
Score = 139 bits (337), Expect = 3e-32
Identities = 90/297 (30%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 59 CTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPG 118
C C E C +G C+P W CD DC DGSDE C CG + TC G
Sbjct: 255 CEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTC--SSG 312
Query: 119 ECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEV 178
C+PL +CD DC DG+DE + C C +G+C+ + E
Sbjct: 313 HCLPLALLCDRQDDCGDGTDEP--SYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEE 370
Query: 179 KC-PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDE-VGCVSTPKVRSPCISTEFE 236
C TC P SC DG C+ A CDG DC DG+DE G P + +P ST
Sbjct: 371 SCLGQVTCVP-GEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPAST--- 426
Query: 237 CNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVK 296
+ L C +F+C C P C+ +
Sbjct: 427 ------------LPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEE 474
Query: 297 DCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE 353
DC DGSDE C C G C+ ++CD CP+ DE D C E
Sbjct: 475 DCADGSDERGCGGP---CAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACVE 528
Score = 111 bits (268), Expect = 7e-24
Identities = 87/288 (30%), Positives = 114/288 (39%), Gaps = 34/288 (11%)
Query: 23 CTSSEFRCK-TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C E C+ G C+P W CDN+ DC D SDE+ C A C E + C S G C+P
Sbjct: 262 CAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEG--CAAPG--CGEGQMTC-SSGHCLP 316
Query: 82 RSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA 141
+ CD DC DG+DE C C G C+P +CD +PDC D +DE++
Sbjct: 317 LALLCDRQDDCGDGTDEPS---YPCPQGLLAC--ADGRCLPPALLCDGHPDCLDAADEES 371
Query: 142 C--NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTDGQ 197
C TC E +C +G C+ + E CP P+ P S G
Sbjct: 372 CLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSL-PTPPASTLPGP 430
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
G +D A +++ PC EF C C R W
Sbjct: 431 -------SPGSLDTASSP-----LASASPAPPCGPFEFRCGSG-ECTPRGWRCDQEEDCA 477
Query: 258 XXXXEALELCRGNVTCRLDQFQC-KDHSCIPGALYCNGVKDCPDGSDE 304
E C G C C + C+ C+GV+ CPDGSDE
Sbjct: 478 DGSDE--RGCGG--PCAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDE 521
Score = 94.7 bits (225), Expect = 1e-18
Identities = 90/335 (26%), Positives = 120/335 (35%), Gaps = 47/335 (14%)
Query: 20 SRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
S C C GRC+P + CD DC D++DE+ C ++ C C+ DG C
Sbjct: 335 SYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEES--CLG-QVTCVPGEVSCV-DGTC 390
Query: 80 IPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDE 139
+ CD DCPDG+DE GP P P + + +P D +
Sbjct: 391 LGAIQLCDGVWDCPDGADE--------GPGHCPLPSLP--TPPASTLPGPSPGSLDTASS 440
Query: 140 KACNET----CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD 195
+ + C EF CG+G+C W E C P C P H C
Sbjct: 441 PLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGP-CAPH-HAPCAR 498
Query: 196 G-QCISAWWHCDGDVDCADGSDE--VGCV---STPKVRSPCISTEFECNDRITCV----- 244
G C+S CDG C DGSDE CV + P +R P + R
Sbjct: 499 GPHCVSPEQLCDGVRQCPDGSDEGPDACVEAPAPPAMRGPPGQAGGPTSSRAPSPPSPPE 558
Query: 245 -----HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
+ L LC G C + C+ C+G+ DCP
Sbjct: 559 AQGEGRKGQERSRTHLTVPAGSTQLPLCPGLFPCGV-----APGLCLTPEQLCDGIPDCP 613
Query: 300 DGSDEYNCTRQKTI-CDKRT-----EFDCGGGMCI 328
G DE +C + RT E+ C G CI
Sbjct: 614 QGEDELDCGGLPALGGPNRTGLPCPEYTCPNGTCI 648
Score = 80.2 bits (189), Expect = 3e-14
Identities = 68/234 (29%), Positives = 89/234 (38%), Gaps = 33/234 (14%)
Query: 74 LSDGLCI-PRSWRCD-ATADCPDGSD-EHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
L G C+ P S C+ P GS + C C ++ C G G C L
Sbjct: 206 LHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELV------ 259
Query: 131 PDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH 190
P C++G E C E NG C+ W+ E C P C +
Sbjct: 260 PACAEG--EALCQE----------NGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG-EGQ 306
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
+C+ G C+ CD DC DG+DE P PC C D C+ A +
Sbjct: 307 MTCSSGHCLPLALLCDRQDDCGDGTDE------PSY--PCPQGLLACADG-RCLPPALLC 357
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
E E C G VTC + C D +C+ C+GV DCPDG+DE
Sbjct: 358 DGHPDCLDAADE--ESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADE 409
Score = 73.3 bits (172), Expect = 3e-12
Identities = 40/103 (38%), Positives = 48/103 (46%), Gaps = 8/103 (7%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDG 77
S + C EFRC +G C P W+CD E+DC+D SDE C C + C
Sbjct: 446 SPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDE--RGCGGP---CAPHHAPCARGP 500
Query: 78 LCIPRSWRCDATADCPDGSDE-HQCEVEACGPEEFTCRGKPGE 119
C+ CD CPDGSDE VEA P RG PG+
Sbjct: 501 HCVSPEQLCDGVRQCPDGSDEGPDACVEAPAPP--AMRGPPGQ 541
Score = 58.8 bits (136), Expect = 7e-08
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 273 CRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
C + C+++ C+P C+ DC DGSDE C C + + C G C+PL+
Sbjct: 262 CAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPG--CGEG-QMTCSSGHCLPLA 318
Query: 332 KVCDKHVDCPNFEDEPRDRCGENECEKNNGGC 363
+CD+ DC + DEP C + +G C
Sbjct: 319 LLCDRQDDCGDGTDEPSYPCPQGLLACADGRC 350
Score = 44.8 bits (101), Expect = 0.001
Identities = 45/169 (26%), Positives = 57/169 (33%), Gaps = 31/169 (18%)
Query: 23 CTSSEFRCKTG-RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C C G C+ CD + C D SDE P C + G P
Sbjct: 489 CAPHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACVEAPAPPAMRGPPGQAGG---P 545
Query: 82 RSWRCDATADCPDGSDEHQ----------------CEVEACGPEEFTCRGKPGECVPLTW 125
S R + P+ E + ++ C P F C PG C+
Sbjct: 546 TSSRAPSPPSPPEAQGEGRKGQERSRTHLTVPAGSTQLPLC-PGLFPCGVAPGLCLTPEQ 604
Query: 126 MCDDNPDCSDGSDEKAC---------NET-CRSDEFTCGNGKCIQMRWV 164
+CD PDC G DE C N T E+TC NG CI + V
Sbjct: 605 LCDGIPDCPQGEDELDCGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLV 653
Score = 35.1 bits (77), Expect = 0.94
Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 13/102 (12%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
Q C + +C G +C G DG +C C + G C+P +CD
Sbjct: 233 QKDCGNCTCQEGQWHCGG-----DGG---HCEELVPACAEGEALCQENGHCVPHGWLCDN 284
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCD 377
DC + DE + C C + CS C+ P+ CD
Sbjct: 285 QDDCGDGSDE--EGCAAPGCGEGQMTCSSGHCL--PLALLCD 322
>AC108036-1|AAX93208.1| 449|Homo sapiens unknown protein.
Length = 449
Score = 134 bits (324), Expect = 1e-30
Identities = 75/218 (34%), Positives = 98/218 (44%), Gaps = 21/218 (9%)
Query: 18 SESRTCTS-SEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+++ +C + SEF C G CI CD C D SDE C C+ F+ +
Sbjct: 238 TKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRS--CRR-GFKPCYN 294
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDG 136
CIP CD DC D SDE C+V C EF C G C+P + C+ N DC+D
Sbjct: 295 RRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD--GTCIPRSARCNQNIDCADA 352
Query: 137 SDEKACNETCRSDEFTCG-----------NGKCIQMRWVXXXXXXXXXXXXEVKCPTPT- 184
SDEK CN T + + G C+ W+ E+KCP
Sbjct: 353 SDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNK 412
Query: 185 --CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
C+ +++FSC G+CI W CDG DC DG DE C
Sbjct: 413 HKCE-ENYFSCPSGRCILNTWICDGQKDCEDGRDEFHC 449
Score = 131 bits (316), Expect = 1e-29
Identities = 74/242 (30%), Positives = 125/242 (51%), Gaps = 16/242 (6%)
Query: 513 DGLAVDWVYNHLYWTD------TGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEGW 566
+GLA ++ LYWT T H + + ++ + P +AL+ +
Sbjct: 5 EGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNL 64
Query: 567 MFWTDWG-QVPKIERAGMDGSHRSTIVSYDVKWPNGLTLDLVRQRVYWVDAKMNTISSCN 625
MFWT+W Q P I R+ + G + +VS D+ PNGLT+D +++Y+ D + I C
Sbjct: 65 MFWTNWNEQHPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCE 124
Query: 626 YDGSGRRLILHSTEVLRHPFSITTFEDWVYWTDWDKTAVYRANKFNGKDVEAITSTHTLQ 685
YDGS R +I+ S S+ ++++++W+DW + A+ R+NK+ G D + + S Q
Sbjct: 125 YDGSQRHVIVKSGPGTF--LSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIPHQ 182
Query: 686 NPMVIHVYHPYRQPDGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQM 745
+I V + + ++ CA +NG C LCL P + RV+C+C G ++L +D
Sbjct: 183 PMGIIAVANDTNSCE-LSPCALLNGGCHDLCLLTP-----NGRVNCSC-RGDRILLEDNR 235
Query: 746 CV 747
CV
Sbjct: 236 CV 237
Score = 108 bits (259), Expect = 8e-23
Identities = 63/162 (38%), Positives = 77/162 (47%), Gaps = 19/162 (11%)
Query: 16 LFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE-DPTVCTATKMVCQEYRFECL 74
L+ E+R+C C RCIP CD E DC D+SDE D V T C F C
Sbjct: 278 LYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVST-----CATVEFRC- 331
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEAC------GPEE--FTCRGKPGECVPLTWM 126
+DG CIPRS RC+ DC D SDE C C G + F CV TW+
Sbjct: 332 ADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWI 391
Query: 127 CDDNPDCSDGSDEKAC----NETCRSDEFTCGNGKCIQMRWV 164
CD + DC D SDE C C + F+C +G+CI W+
Sbjct: 392 CDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWI 433
Score = 105 bits (253), Expect = 4e-22
Identities = 64/205 (31%), Positives = 81/205 (39%), Gaps = 10/205 (4%)
Query: 110 EFTCRGKPGECVPLTWMCDDNPDCSDGSDEKA--C-NETCRSDEFTCGNGKCIQMRWVXX 166
EF C GEC+ CD P C D SDEK C N +CR C N +CI +
Sbjct: 248 EFECGN--GECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCD 305
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKV 226
E+ C TC F C DG CI C+ ++DCAD SDE C +T
Sbjct: 306 GENDCGDNSDELDCKVSTCATVE-FRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCT 364
Query: 227 RSPCISTE----FECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD 282
+ + CN CV W+ E + C + F C
Sbjct: 365 HFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPS 424
Query: 283 HSCIPGALYCNGVKDCPDGSDEYNC 307
CI C+G KDC DG DE++C
Sbjct: 425 GRCILNTWICDGQKDCEDGRDEFHC 449
Score = 91.9 bits (218), Expect = 8e-18
Identities = 70/249 (28%), Positives = 91/249 (36%), Gaps = 23/249 (9%)
Query: 18 SESRTCTSSEFRCKTGRCIPLSWKCDNEK-DCSDSSDE---DPTVCTATKMVCQEY-RFE 72
+++ +C S G C L N + +CS D + C C Y FE
Sbjct: 191 NDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFE 250
Query: 73 CLSDGLCIPRSWRCDATADCPDGSDEH--QCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
C +G CI CD C D SDE CE +C C + C+P +CD
Sbjct: 251 C-GNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNR--RCIPHGKLCDGE 307
Query: 131 PDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTC---- 185
DC D SDE C TC + EF C +G CI E C C
Sbjct: 308 NDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFY 367
Query: 186 ----QPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDR 240
+ C + C+ W CDG DC D SDE+ C K + C F C
Sbjct: 368 KLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHK--CEENYFSCPSG 425
Query: 241 ITCVHRAWV 249
C+ W+
Sbjct: 426 -RCILNTWI 433
Score = 82.2 bits (194), Expect = 6e-15
Identities = 66/217 (30%), Positives = 90/217 (41%), Gaps = 23/217 (10%)
Query: 143 NETCRS-DEFTCGNGKCIQMRWVXXXXXXXXXXXXE--VKCPTPTCQPQSHFSCTDGQCI 199
N +C + EF CGNG+CI + E + C +C+ + C + +CI
Sbjct: 240 NSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCR-RGFKPCYNRRCI 298
Query: 200 SAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXX 259
CDG+ DC D SDE+ C KV S C + EF C D TC+ R+
Sbjct: 299 PHGKLCDGENDCGDNSDELDC----KV-STCATVEFRCADG-TCIPRSARCNQNIDCADA 352
Query: 260 XXEALELCRGNVTC--------RLDQF-QCKDHS-CIPGALYCNGVKDCPDGSDEYNCTR 309
E + C N C + F +C S C+ C+G DC D SDE C
Sbjct: 353 SDE--KNCN-NTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPV 409
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
Q + F C G CI + +CD DC + DE
Sbjct: 410 QNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDE 446
Score = 75.4 bits (177), Expect = 7e-13
Identities = 64/206 (31%), Positives = 94/206 (45%), Gaps = 18/206 (8%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
+C S F C +G+CI CDG C D SDE + + RS C C +R C
Sbjct: 242 SCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEK--LLYCENRS-CRRGFKPCYNR-RC 297
Query: 244 VHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSD 303
+ + E L+ C+ + TC +F+C D +CIP + CN DC D SD
Sbjct: 298 IPHGKLCDGENDCGDNSDE-LD-CKVS-TCATVEFRCADGTCIPRSARCNQNIDCADASD 354
Query: 304 EYN-----CTRQKTICDKRTEF-DCGG-GMCIPLSKVCDKHVDCPNFEDEPRDRC-GENE 355
E N CT + K T F C +C+ + +CD DC ++ DE + +++
Sbjct: 355 EKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHK 414
Query: 356 CEKNNGGC-SQRCVDTPIGYYCDCEK 380
CE+N C S RC+ + CD +K
Sbjct: 415 CEENYFSCPSGRCILNT--WICDGQK 438
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 303 DEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGG 362
++ C + + C+ +EF+CG G CI CD C + DE C C +
Sbjct: 232 EDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKP 291
Query: 363 C-SQRCVDTPIGYYC----DCEKGYKLIDNR--TCEDID-ECADPGSC 402
C ++RC+ P G C DC +D + TC ++ CAD G+C
Sbjct: 292 CYNRRCI--PHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD-GTC 336
Score = 51.2 bits (117), Expect = 1e-05
Identities = 24/98 (24%), Positives = 54/98 (55%), Gaps = 5/98 (5%)
Query: 479 MIFWSDVNDE--KIYKAPIDEGTQRTVVIGEQLITSDGLAVDWVYNHLYWTDTGHNHIEL 536
++FW++ N++ I ++ + G VV+ ++T +GL +D+ LY++D IE
Sbjct: 64 LMFWTNWNEQHPSIMRSTLT-GKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIER 122
Query: 537 SDLQGNMRKILIRDRLEEPRAIALNPLEGWMFWTDWGQ 574
+ G+ R ++++ ++L + ++FW+DWG+
Sbjct: 123 CEYDGSQRHVIVKS--GPGTFLSLAVYDNYIFWSDWGR 158
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 121 bits (291), Expect = 1e-26
Identities = 73/221 (33%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 197 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 253
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 254 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 311
Query: 135 DGSDEKACNET--CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTP----TCQPQ 188
DGSDE C C +EF CGNG C W E CPT C P
Sbjct: 312 DGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 371
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP 229
+ CI A +HCD + DC D SDE GC+ P+V +P
Sbjct: 372 QFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM-PPQVVTP 411
Score = 101 bits (242), Expect = 1e-20
Identities = 75/241 (31%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 198 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 256
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 257 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 313
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA-LELCRGNVTC 273
SDE+ C P PC EF C + C + W EA R C
Sbjct: 314 SDELDCGPPP----PCEPNEFPCGNG-HCALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 368
Query: 274 RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
QF+C + CIP + +C+ DCPD SDE+ C + + R G + +
Sbjct: 369 GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTC 428
Query: 333 V 333
V
Sbjct: 429 V 429
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +EF C G C W+CD + DC D +DE + VC +F C+S +CIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPA 384
Query: 83 SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLT 124
S+ CD +DCPD SDE C + P + + G+ V T
Sbjct: 385 SFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFT 427
Score = 75.4 bits (177), Expect = 7e-13
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 196 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 252
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 253 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 310
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
DGSDE +C C+ EF CG G C CD DC + DE C E+
Sbjct: 311 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDCEDRTDEA--NCPTKRPEE 366
Query: 359 NNGGCSQRCVDT----PIGYYCDCE 379
G RCV T P ++CD E
Sbjct: 367 VCGPTQFRCVSTNMCIPASFHCDEE 391
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT--RQKTICDKRTEFDC-GGGMCIP 329
C ++F C + C C+G DC D +DE NC R + +C T+F C MCIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGP-TQFRCVSTNMCIP 383
Query: 330 LSKVCDKHVDCPNFEDE 346
S CD+ DCP+ DE
Sbjct: 384 ASFHCDEESDCPDRSDE 400
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 121 bits (291), Expect = 1e-26
Identities = 73/221 (33%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 197 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 253
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 254 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 311
Query: 135 DGSDEKACNET--CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTP----TCQPQ 188
DGSDE C C +EF CGNG C W E CPT C P
Sbjct: 312 DGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 371
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP 229
+ CI A +HCD + DC D SDE GC+ P+V +P
Sbjct: 372 QFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM-PPQVVTP 411
Score = 101 bits (242), Expect = 1e-20
Identities = 75/241 (31%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 198 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 256
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 257 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 313
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA-LELCRGNVTC 273
SDE+ C P PC EF C + C + W EA R C
Sbjct: 314 SDELDCGPPP----PCEPNEFPCGNG-HCALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 368
Query: 274 RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
QF+C + CIP + +C+ DCPD SDE+ C + + R G + +
Sbjct: 369 GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTC 428
Query: 333 V 333
V
Sbjct: 429 V 429
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +EF C G C W+CD + DC D +DE + VC +F C+S +CIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPA 384
Query: 83 SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLT 124
S+ CD +DCPD SDE C + P + + G+ V T
Sbjct: 385 SFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFT 427
Score = 75.4 bits (177), Expect = 7e-13
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 196 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 252
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 253 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 310
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
DGSDE +C C+ EF CG G C CD DC + DE C E+
Sbjct: 311 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDCEDRTDEA--NCPTKRPEE 366
Query: 359 NNGGCSQRCVDT----PIGYYCDCE 379
G RCV T P ++CD E
Sbjct: 367 VCGPTQFRCVSTNMCIPASFHCDEE 391
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT--RQKTICDKRTEFDC-GGGMCIP 329
C ++F C + C C+G DC D +DE NC R + +C T+F C MCIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGP-TQFRCVSTNMCIP 383
Query: 330 LSKVCDKHVDCPNFEDE 346
S CD+ DCP+ DE
Sbjct: 384 ASFHCDEESDCPDRSDE 400
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate
proteoglycan 2 (perlecan) protein.
Length = 4391
Score = 121 bits (291), Expect = 1e-26
Identities = 73/221 (33%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 197 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 253
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 254 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 311
Query: 135 DGSDEKACNET--CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTP----TCQPQ 188
DGSDE C C +EF CGNG C W E CPT C P
Sbjct: 312 DGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 371
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP 229
+ CI A +HCD + DC D SDE GC+ P+V +P
Sbjct: 372 QFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM-PPQVVTP 411
Score = 101 bits (242), Expect = 1e-20
Identities = 75/241 (31%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 198 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 256
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 257 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 313
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA-LELCRGNVTC 273
SDE+ C P PC EF C + C + W EA R C
Sbjct: 314 SDELDCGPPP----PCEPNEFPCGNG-HCALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 368
Query: 274 RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
QF+C + CIP + +C+ DCPD SDE+ C + + R G + +
Sbjct: 369 GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTC 428
Query: 333 V 333
V
Sbjct: 429 V 429
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +EF C G C W+CD + DC D +DE + VC +F C+S +CIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPA 384
Query: 83 SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLT 124
S+ CD +DCPD SDE C + P + + G+ V T
Sbjct: 385 SFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFT 427
Score = 75.4 bits (177), Expect = 7e-13
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 196 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 252
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 253 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 310
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
DGSDE +C C+ EF CG G C CD DC + DE C E+
Sbjct: 311 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDCEDRTDEA--NCPTKRPEE 366
Query: 359 NNGGCSQRCVDT----PIGYYCDCE 379
G RCV T P ++CD E
Sbjct: 367 VCGPTQFRCVSTNMCIPASFHCDEE 391
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT--RQKTICDKRTEFDC-GGGMCIP 329
C ++F C + C C+G DC D +DE NC R + +C T+F C MCIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGP-TQFRCVSTNMCIP 383
Query: 330 LSKVCDKHVDCPNFEDE 346
S CD+ DCP+ DE
Sbjct: 384 ASFHCDEESDCPDRSDE 400
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate
proteoglycan 2 (perlecan) protein.
Length = 4391
Score = 121 bits (291), Expect = 1e-26
Identities = 73/221 (33%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 197 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 253
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 254 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 311
Query: 135 DGSDEKACNET--CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTP----TCQPQ 188
DGSDE C C +EF CGNG C W E CPT C P
Sbjct: 312 DGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 371
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP 229
+ CI A +HCD + DC D SDE GC+ P+V +P
Sbjct: 372 QFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM-PPQVVTP 411
Score = 101 bits (242), Expect = 1e-20
Identities = 75/241 (31%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 198 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 256
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 257 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 313
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA-LELCRGNVTC 273
SDE+ C P PC EF C + C + W EA R C
Sbjct: 314 SDELDCGPPP----PCEPNEFPCGNG-HCALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 368
Query: 274 RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
QF+C + CIP + +C+ DCPD SDE+ C + + R G + +
Sbjct: 369 GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTC 428
Query: 333 V 333
V
Sbjct: 429 V 429
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +EF C G C W+CD + DC D +DE + VC +F C+S +CIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPA 384
Query: 83 SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLT 124
S+ CD +DCPD SDE C + P + + G+ V T
Sbjct: 385 SFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFT 427
Score = 75.4 bits (177), Expect = 7e-13
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 196 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 252
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 253 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 310
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
DGSDE +C C+ EF CG G C CD DC + DE C E+
Sbjct: 311 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDCEDRTDEA--NCPTKRPEE 366
Query: 359 NNGGCSQRCVDT----PIGYYCDCE 379
G RCV T P ++CD E
Sbjct: 367 VCGPTQFRCVSTNMCIPASFHCDEE 391
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT--RQKTICDKRTEFDC-GGGMCIP 329
C ++F C + C C+G DC D +DE NC R + +C T+F C MCIP
Sbjct: 325 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGP-TQFRCVSTNMCIP 383
Query: 330 LSKVCDKHVDCPNFEDE 346
S CD+ DCP+ DE
Sbjct: 384 ASFHCDEESDCPDRSDE 400
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate
proteoglycan perlecan protein.
Length = 4370
Score = 121 bits (291), Expect = 1e-26
Identities = 73/221 (33%), Positives = 92/221 (41%), Gaps = 18/221 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 176 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 232
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 233 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 290
Query: 135 DGSDEKACNET--CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTP----TCQPQ 188
DGSDE C C +EF CGNG C W E CPT C P
Sbjct: 291 DGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPT 350
Query: 189 SHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP 229
+ CI A +HCD + DC D SDE GC+ P+V +P
Sbjct: 351 QFRCVSTNMCIPASFHCDEESDCPDRSDEFGCM-PPQVVTP 390
Score = 101 bits (242), Expect = 1e-20
Identities = 75/241 (31%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 177 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 235
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 236 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 292
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEA-LELCRGNVTC 273
SDE+ C P PC EF C + C + W EA R C
Sbjct: 293 SDELDCGPPP----PCEPNEFPCGNG-HCALKLWRCDGDFDCEDRTDEANCPTKRPEEVC 347
Query: 274 RLDQFQC-KDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
QF+C + CIP + +C+ DCPD SDE+ C + + R G + +
Sbjct: 348 GPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTC 407
Query: 333 V 333
V
Sbjct: 408 V 408
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/103 (35%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C +EF C G C W+CD + DC D +DE + VC +F C+S +CIP
Sbjct: 304 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPA 363
Query: 83 SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLT 124
S+ CD +DCPD SDE C + P + + G+ V T
Sbjct: 364 SFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFT 406
Score = 75.4 bits (177), Expect = 7e-13
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 17/205 (8%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 175 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 231
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 232 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 289
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEK 358
DGSDE +C C+ EF CG G C CD DC + DE C E+
Sbjct: 290 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDCEDRTDEA--NCPTKRPEE 345
Query: 359 NNGGCSQRCVDT----PIGYYCDCE 379
G RCV T P ++CD E
Sbjct: 346 VCGPTQFRCVSTNMCIPASFHCDEE 370
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT--RQKTICDKRTEFDC-GGGMCIP 329
C ++F C + C C+G DC D +DE NC R + +C T+F C MCIP
Sbjct: 304 CEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGP-TQFRCVSTNMCIP 362
Query: 330 LSKVCDKHVDCPNFEDE 346
S CD+ DCP+ DE
Sbjct: 363 ASFHCDEESDCPDRSDE 379
>BC110451-1|AAI10452.1| 1042|Homo sapiens corin, serine peptidase
protein.
Length = 1042
Score = 116 bits (279), Expect = 3e-25
Identities = 61/151 (40%), Positives = 77/151 (50%), Gaps = 12/151 (7%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C S G+CIP +C+ DC D SDE C C F C G+C+ + +CD
Sbjct: 275 FLCAS-GICIPGKLQCNGYNDCDDWSDEAHCN---CSENLFHCH--TGKCLNYSLVCDGY 328
Query: 131 PDCSDGSDEKACNETCR-SDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC D SDE+ C+ C + E CG+G+CI M WV EV C +C Q
Sbjct: 329 DDCGDLSDEQNCD--CNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNC---SCHSQG 383
Query: 190 HFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
C +GQCI + + CDGD DC DGSDE C
Sbjct: 384 LVECRNGQCIPSTFQCDGDEDCKDGSDEENC 414
Score = 103 bits (246), Expect = 3e-21
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 14/140 (10%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C+ + F C TG+C+ S CD DC D SDE C T E+R C DG CI
Sbjct: 306 CSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPT----TEHR--C-GDGRCIAM 358
Query: 83 SWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
W CD DC D SDE C + G E CR G+C+P T+ CD + DC DGSDE+ C
Sbjct: 359 EWVCDGDHDCVDKSDEVNCSCHSQGLVE--CRN--GQCIPSTFQCDGDEDCKDGSDEENC 414
Query: 143 N---ETCRSDEFTCGNGKCI 159
+ +C+ + C C+
Sbjct: 415 SVIQTSCQEGDQRCLYNPCL 434
Score = 89.4 bits (212), Expect = 4e-17
Identities = 44/120 (36%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C+ S F+C++G+C+ S +CD + DC D SDE+ C + +EC S+ C+
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDL------WECPSNKQCLKH 633
Query: 83 SWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
+ CD DCPD DE C C +E C CV CD DCSD SDE C
Sbjct: 634 TVICDGFPDCPDYMDEKNCSF--CQDDELECANH--ACVSRDLWCDGEADCSDSSDEWDC 689
Score = 88.2 bits (209), Expect = 1e-16
Identities = 51/144 (35%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 106 CGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
CG E F C G C+P C+ DC D SDE CN C + F C GKC+ V
Sbjct: 269 CGRGENFLCAS--GICIPGKLQCNGYNDCDDWSDEAHCN--CSENLFHCHTGKCLNYSLV 324
Query: 165 XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
E C C P + C DG+CI+ W CDGD DC D SDEV C
Sbjct: 325 CDGYDDCGDLSDEQNCD---CNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHS 381
Query: 225 K-----VRSPCISTEFECNDRITC 243
+ CI + F+C+ C
Sbjct: 382 QGLVECRNGQCIPSTFQCDGDEDC 405
Score = 87.0 bits (206), Expect = 2e-16
Identities = 53/134 (39%), Positives = 64/134 (47%), Gaps = 17/134 (12%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
F C +G CIP +C+ DC D SDE C C E F C G C+ S CD
Sbjct: 275 FLCASGICIPGKLQCNGYNDCDDWSDE--AHCN-----CSENLFHC-HTGKCLNYSLVCD 326
Query: 88 ATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
DC D SDE C+ C P E C G C+ + W+CD + DC D SDE C +C
Sbjct: 327 GYDDCGDLSDEQNCD---CNPTTEHRC--GDGRCIAMEWVCDGDHDCVDKSDEVNC--SC 379
Query: 147 RSDEFT-CGNGKCI 159
S C NG+CI
Sbjct: 380 HSQGLVECRNGQCI 393
Score = 78.2 bits (184), Expect = 1e-13
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 29/208 (13%)
Query: 133 CSDGSDEKACNETC-RSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHF 191
C E C R + F C +G CI + E C C ++ F
Sbjct: 256 CFSPQQENGKQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC---NCS-ENLF 311
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+C++ CDG DC D SDE C P +TE C D C+ WV
Sbjct: 312 HCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNP-------TTEHRCGDG-RCIAMEWVCD 363
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQF-QCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E N +C +C++ CIP C+G +DC DGSDE NC+
Sbjct: 364 GDHDCVDKSDEV------NCSCHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVI 417
Query: 311 KTIC---DKRTEFD-----CGG-GMCIP 329
+T C D+R ++ CGG +C P
Sbjct: 418 QTSCQEGDQRCLYNPCLDSCGGSSLCDP 445
Score = 77.4 bits (182), Expect = 2e-13
Identities = 60/210 (28%), Positives = 83/210 (39%), Gaps = 21/210 (10%)
Query: 185 CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
C +F C G CI C+G DC D SDE C C F C+ C+
Sbjct: 269 CGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC--------NCSENLFHCHTG-KCL 319
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
+ + V E + C N T + +C D CI C+G DC D SDE
Sbjct: 320 NYSLVCDGYDDCGDLSDE--QNCDCNPTT---EHRCGDGRCIAMEWVCDGDHDCVDKSDE 374
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
NC+ C + +C G CIP + CD DC + DE + C++ + C
Sbjct: 375 VNCS-----CHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCL 429
Query: 365 QR-CVDTPIGYYCDCEKGYKLIDNRTCEDI 393
C+D+ G C+ L + CE I
Sbjct: 430 YNPCLDS-CGGSSLCDPNNSLNNCSQCEPI 458
Score = 76.6 bits (180), Expect = 3e-13
Identities = 45/126 (35%), Positives = 62/126 (49%), Gaps = 11/126 (8%)
Query: 25 SSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSW 84
++E RC GRCI + W CD + DC D SDE C + +V EC +G CIP ++
Sbjct: 345 TTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLV------EC-RNGQCIPSTF 397
Query: 85 RCDATADCPDGSDEHQCEV--EACGPEEFTCRGKPG-ECVPLTWMCDDNPDCSDGSD-EK 140
+CD DC DGSDE C V +C + C P + + +CD N ++ S E
Sbjct: 398 QCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSLNNCSQCEP 457
Query: 141 ACNETC 146
E C
Sbjct: 458 ITLELC 463
Score = 72.5 bits (170), Expect = 5e-12
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 20/171 (11%)
Query: 63 KMVCQEYRFECLSDGLCIPRSWRCDATADCP----DGSDEHQC-----EVEACGPEEFTC 113
+ +C+ + C S + W D DC + SD C VE C P F C
Sbjct: 530 RALCEHSKERCESVLGIVGLQWPEDT--DCSQFPEENSDNQTCLMPDEYVEECSPSHFKC 587
Query: 114 RGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRS-DEFTC-GNGKCIQMRWVXXXXXXX 171
R G+CV + CD DC D SDE+ C C+ D + C N +C++ +
Sbjct: 588 RS--GQCVLASRRCDGQADCDDDSDEENCG--CKERDLWECPSNKQCLKHTVICDGFPDC 643
Query: 172 XXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVS 222
E C CQ C + C+S CDG+ DC+D SDE CV+
Sbjct: 644 PDYMDEKNCSF--CQ-DDELECANHACVSRDLWCDGEADCSDSSDEWDCVT 691
Score = 72.5 bits (170), Expect = 5e-12
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 13/123 (10%)
Query: 185 CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
C P SHF C GQC+ A CDG DC D SDE C + +EC C+
Sbjct: 580 CSP-SHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKER-------DLWECPSNKQCL 631
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
+ E + C+ D+ +C +H+C+ L+C+G DC D SDE
Sbjct: 632 KHTVICDGFPDCPDYMDE-----KNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDE 686
Query: 305 YNC 307
++C
Sbjct: 687 WDC 689
Score = 69.3 bits (162), Expect = 5e-11
Identities = 72/326 (22%), Positives = 116/326 (35%), Gaps = 35/326 (10%)
Query: 30 CKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
C+ G+CIP +++CD ++DC D SDE+ C+ + CQE CL + C+ C +
Sbjct: 387 CRNGQCIPSTFQCDGDEDCKDGSDEEN--CSVIQTSCQEGDQRCLYNP-CLDS---CGGS 440
Query: 90 ADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSD 149
+ C + + C C P C+ L + P+ +K + + S
Sbjct: 441 SLCDPNNSLNNCS--QCEPITLEL------CMNLPYNSTSYPNYFGHRTQKEASISWESS 492
Query: 150 EFTC-GNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISA--WWHCD 206
F C + P C+ S + +
Sbjct: 493 LFPALVQTNCYKYLMFFSCTILVPKCDVNTGERIPPCRALCEHSKERCESVLGIVGLQWP 552
Query: 207 GDVDCA----DGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXE 262
D DC+ + SD C+ + C + F+C CV + E
Sbjct: 553 EDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSG-QCVLASRRCDGQADCDDDSDE 611
Query: 263 ALELCRGNVTCR-LDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
N C+ D ++C + C+ + C+G DCPD DE NC+ C E
Sbjct: 612 E------NCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCS----FCQD-DEL 660
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE 346
+C C+ CD DC + DE
Sbjct: 661 ECANHACVSRDLWCDGEADCSDSSDE 686
Score = 62.1 bits (144), Expect = 7e-09
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLS 331
C F+C+ C+ + C+G DC D SDE NC C +R ++C C+ +
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCG-----CKERDLWECPSNKQCLKHT 634
Query: 332 KVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQR 366
+CD DCP++ DE C ++E E N C R
Sbjct: 635 VICDGFPDCPDYMDEKNCSFCQDDELECANHACVSR 670
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 15/121 (12%)
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGC------ 363
++ +C + F C G+CIP C+ + DC ++ DE C EN + G C
Sbjct: 265 KQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLV 324
Query: 364 ---SQRCVDTPIGYYCDCE--KGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECH 418
C D CDC ++ D R C ++ D C+++ C CH
Sbjct: 325 CDGYDDCGDLSDEQNCDCNPTTEHRCGDGR-CIAMEWVCDG---DHDCVDKSDEVNCSCH 380
Query: 419 T 419
+
Sbjct: 381 S 381
>AF133845-1|AAD31850.1| 1042|Homo sapiens corin protein.
Length = 1042
Score = 116 bits (279), Expect = 3e-25
Identities = 61/151 (40%), Positives = 77/151 (50%), Gaps = 12/151 (7%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C S G+CIP +C+ DC D SDE C C F C G+C+ + +CD
Sbjct: 275 FLCAS-GICIPGKLQCNGYNDCDDWSDEAHCN---CSENLFHCH--TGKCLNYSLVCDGY 328
Query: 131 PDCSDGSDEKACNETCR-SDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQS 189
DC D SDE+ C+ C + E CG+G+CI M WV EV C +C Q
Sbjct: 329 DDCGDLSDEQNCD--CNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNC---SCHSQG 383
Query: 190 HFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
C +GQCI + + CDGD DC DGSDE C
Sbjct: 384 LVECRNGQCIPSTFQCDGDEDCKDGSDEENC 414
Score = 103 bits (246), Expect = 3e-21
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 14/140 (10%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C+ + F C TG+C+ S CD DC D SDE C T E+R C DG CI
Sbjct: 306 CSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPT----TEHR--C-GDGRCIAM 358
Query: 83 SWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
W CD DC D SDE C + G E CR G+C+P T+ CD + DC DGSDE+ C
Sbjct: 359 EWVCDGDHDCVDKSDEVNCSCHSQGLVE--CRN--GQCIPSTFQCDGDEDCKDGSDEENC 414
Query: 143 N---ETCRSDEFTCGNGKCI 159
+ +C+ + C C+
Sbjct: 415 SVIQTSCQEGDQRCLYNPCL 434
Score = 89.4 bits (212), Expect = 4e-17
Identities = 44/120 (36%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C+ S F+C++G+C+ S +CD + DC D SDE+ C + +EC S+ C+
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDL------WECPSNKQCLKH 633
Query: 83 SWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
+ CD DCPD DE C C +E C CV CD DCSD SDE C
Sbjct: 634 TVICDGFPDCPDYMDEKNCSF--CQDDELECANH--ACVSRDLWCDGEADCSDSSDEWDC 689
Score = 88.2 bits (209), Expect = 1e-16
Identities = 51/144 (35%), Positives = 62/144 (43%), Gaps = 13/144 (9%)
Query: 106 CGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
CG E F C G C+P C+ DC D SDE CN C + F C GKC+ V
Sbjct: 269 CGRGENFLCAS--GICIPGKLQCNGYNDCDDWSDEAHCN--CSENLFHCHTGKCLNYSLV 324
Query: 165 XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
E C C P + C DG+CI+ W CDGD DC D SDEV C
Sbjct: 325 CDGYDDCGDLSDEQNCD---CNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHS 381
Query: 225 K-----VRSPCISTEFECNDRITC 243
+ CI + F+C+ C
Sbjct: 382 QGLVECRNGQCIPSTFQCDGDEDC 405
Score = 87.0 bits (206), Expect = 2e-16
Identities = 53/134 (39%), Positives = 64/134 (47%), Gaps = 17/134 (12%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
F C +G CIP +C+ DC D SDE C C E F C G C+ S CD
Sbjct: 275 FLCASGICIPGKLQCNGYNDCDDWSDE--AHCN-----CSENLFHC-HTGKCLNYSLVCD 326
Query: 88 ATADCPDGSDEHQCEVEACGP-EEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETC 146
DC D SDE C+ C P E C G C+ + W+CD + DC D SDE C +C
Sbjct: 327 GYDDCGDLSDEQNCD---CNPTTEHRC--GDGRCIAMEWVCDGDHDCVDKSDEVNC--SC 379
Query: 147 RSDEFT-CGNGKCI 159
S C NG+CI
Sbjct: 380 HSQGLVECRNGQCI 393
Score = 78.2 bits (184), Expect = 1e-13
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 29/208 (13%)
Query: 133 CSDGSDEKACNETC-RSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHF 191
C E C R + F C +G CI + E C C ++ F
Sbjct: 256 CFSPQQENGKQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC---NCS-ENLF 311
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
C G+C++ CDG DC D SDE C P +TE C D C+ WV
Sbjct: 312 HCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNP-------TTEHRCGDG-RCIAMEWVCD 363
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQF-QCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E N +C +C++ CIP C+G +DC DGSDE NC+
Sbjct: 364 GDHDCVDKSDEV------NCSCHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVI 417
Query: 311 KTIC---DKRTEFD-----CGG-GMCIP 329
+T C D+R ++ CGG +C P
Sbjct: 418 QTSCQEGDQRCLYNPCLDSCGGSSLCDP 445
Score = 77.4 bits (182), Expect = 2e-13
Identities = 60/210 (28%), Positives = 83/210 (39%), Gaps = 21/210 (10%)
Query: 185 CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
C +F C G CI C+G DC D SDE C C F C+ C+
Sbjct: 269 CGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHC--------NCSENLFHCHTG-KCL 319
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
+ + V E + C N T + +C D CI C+G DC D SDE
Sbjct: 320 NYSLVCDGYDDCGDLSDE--QNCDCNPTT---EHRCGDGRCIAMEWVCDGDHDCVDKSDE 374
Query: 305 YNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCS 364
NC+ C + +C G CIP + CD DC + DE + C++ + C
Sbjct: 375 VNCS-----CHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCL 429
Query: 365 QR-CVDTPIGYYCDCEKGYKLIDNRTCEDI 393
C+D+ G C+ L + CE I
Sbjct: 430 YNPCLDS-CGGSSLCDPNNSLNNCSQCEPI 458
Score = 76.6 bits (180), Expect = 3e-13
Identities = 45/126 (35%), Positives = 62/126 (49%), Gaps = 11/126 (8%)
Query: 25 SSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSW 84
++E RC GRCI + W CD + DC D SDE C + +V EC +G CIP ++
Sbjct: 345 TTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLV------EC-RNGQCIPSTF 397
Query: 85 RCDATADCPDGSDEHQCEV--EACGPEEFTCRGKPG-ECVPLTWMCDDNPDCSDGSD-EK 140
+CD DC DGSDE C V +C + C P + + +CD N ++ S E
Sbjct: 398 QCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSLNNCSQCEP 457
Query: 141 ACNETC 146
E C
Sbjct: 458 ITLELC 463
Score = 72.5 bits (170), Expect = 5e-12
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 20/171 (11%)
Query: 63 KMVCQEYRFECLSDGLCIPRSWRCDATADCP----DGSDEHQC-----EVEACGPEEFTC 113
+ +C+ + C S + W D DC + SD C VE C P F C
Sbjct: 530 RALCEHSKERCESVLGIVGLQWPEDT--DCSQFPEENSDNQTCLMPDEYVEECSPSHFKC 587
Query: 114 RGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRS-DEFTC-GNGKCIQMRWVXXXXXXX 171
R G+CV + CD DC D SDE+ C C+ D + C N +C++ +
Sbjct: 588 RS--GQCVLASRRCDGQADCDDDSDEENCG--CKERDLWECPSNKQCLKHTVICDGFPDC 643
Query: 172 XXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVS 222
E C CQ C + C+S CDG+ DC+D SDE CV+
Sbjct: 644 PDYMDEKNCSF--CQ-DDELECANHACVSRDLWCDGEADCSDSSDEWDCVT 691
Score = 72.5 bits (170), Expect = 5e-12
Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 13/123 (10%)
Query: 185 CQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
C P SHF C GQC+ A CDG DC D SDE C + +EC C+
Sbjct: 580 CSP-SHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKER-------DLWECPSNKQCL 631
Query: 245 HRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDE 304
+ E + C+ D+ +C +H+C+ L+C+G DC D SDE
Sbjct: 632 KHTVICDGFPDCPDYMDE-----KNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDE 686
Query: 305 YNC 307
++C
Sbjct: 687 WDC 689
Score = 69.3 bits (162), Expect = 5e-11
Identities = 72/326 (22%), Positives = 116/326 (35%), Gaps = 35/326 (10%)
Query: 30 CKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
C+ G+CIP +++CD ++DC D SDE+ C+ + CQE CL + C+ C +
Sbjct: 387 CRNGQCIPSTFQCDGDEDCKDGSDEEN--CSVIQTSCQEGDQRCLYNP-CLDS---CGGS 440
Query: 90 ADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSD 149
+ C + + C C P C+ L + P+ +K + + S
Sbjct: 441 SLCDPNNSLNNCS--QCEPITLEL------CMNLPYNSTSYPNYFGHRTQKEASISWESS 492
Query: 150 EFTC-GNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISA--WWHCD 206
F C + P C+ S + +
Sbjct: 493 LFPALVQTNCYKYLMFFSCTILVPKCDVNTGERIPPCRALCEHSKERCESVLGIVGLQWP 552
Query: 207 GDVDCA----DGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXE 262
D DC+ + SD C+ + C + F+C CV + E
Sbjct: 553 EDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSG-QCVLASRRCDGQADCDDDSDE 611
Query: 263 ALELCRGNVTCR-LDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF 320
N C+ D ++C + C+ + C+G DCPD DE NC+ C E
Sbjct: 612 E------NCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCS----FCQD-DEL 660
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE 346
+C C+ CD DC + DE
Sbjct: 661 ECANHACVSRDLWCDGEADCSDSSDE 686
Score = 62.1 bits (144), Expect = 7e-09
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLS 331
C F+C+ C+ + C+G DC D SDE NC C +R ++C C+ +
Sbjct: 580 CSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCG-----CKERDLWECPSNKQCLKHT 634
Query: 332 KVCDKHVDCPNFEDEPR-DRCGENECEKNNGGCSQR 366
+CD DCP++ DE C ++E E N C R
Sbjct: 635 VICDGFPDCPDYMDEKNCSFCQDDELECANHACVSR 670
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 15/121 (12%)
Query: 310 QKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGC------ 363
++ +C + F C G+CIP C+ + DC ++ DE C EN + G C
Sbjct: 265 KQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLV 324
Query: 364 ---SQRCVDTPIGYYCDCE--KGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECH 418
C D CDC ++ D R C ++ D C+++ C CH
Sbjct: 325 CDGYDDCGDLSDEQNCDCNPTTEHRCGDGR-CIAMEWVCDG---DHDCVDKSDEVNCSCH 380
Query: 419 T 419
+
Sbjct: 381 S 381
>BC042754-1|AAH42754.2| 345|Homo sapiens low density lipoprotein
receptor class A domain containing 3 protein.
Length = 345
Score = 101 bits (243), Expect = 7e-21
Identities = 48/120 (40%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
F C GRCIP +W+CD DC D SDE C K C F C S CI +RC+
Sbjct: 35 FMCSNGRCIPGAWQCDGLPDCFDKSDEKE--CPKAKSKCGPTFFPCASGIHCIIGRFRCN 92
Query: 88 ATADCPDGSDEHQCEVE--ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNET 145
DCPDGSDE C C + C K G C+ +++CD +C D SDE++C +
Sbjct: 93 GFEDCPDGSDEENCTANPLLCSTARYHC--KNGLCIDKSFICDGQNNCQDNSDEESCESS 150
Score = 81.4 bits (192), Expect = 1e-14
Identities = 44/127 (34%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 182 TPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
T C +F C++G+CI W CDG DC D SDE C PK +S C T F C I
Sbjct: 26 TNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKEC---PKAKSKCGPTFFPCASGI 82
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGN-VTCRLDQFQCKDHSCIPGALYCNGVKDCPD 300
C+ + E E C N + C ++ CK+ CI + C+G +C D
Sbjct: 83 HCIIGRFRCNGFEDCPDGSDE--ENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQD 140
Query: 301 GSDEYNC 307
SDE +C
Sbjct: 141 NSDEESC 147
Score = 73.7 bits (173), Expect = 2e-12
Identities = 44/136 (32%), Positives = 58/136 (42%), Gaps = 11/136 (8%)
Query: 93 PDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNET---CRSD 149
P + ++C + P F C G C+P W CD PDC D SDEK C + C
Sbjct: 21 PGNNFTNECNI----PGNFMCSN--GRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPT 74
Query: 150 EFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAWWHCDG 207
F C +G CI R+ E C P + + C +G CI + CDG
Sbjct: 75 FFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDG 134
Query: 208 DVDCADGSDEVGCVST 223
+C D SDE C S+
Sbjct: 135 QNNCQDNSDEESCESS 150
Score = 67.3 bits (157), Expect = 2e-10
Identities = 39/117 (33%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDH-SCIPGA 289
I F C++ C+ AW E E + C F C CI G
Sbjct: 31 IPGNFMCSNG-RCIPGAWQCDGLPDCFDKSDEK-ECPKAKSKCGPTFFPCASGIHCIIGR 88
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
CNG +DCPDGSDE NCT +C + C G+CI S +CD +C + DE
Sbjct: 89 FRCNGFEDCPDGSDEENCTANPLLC-STARYHCKNGLCIDKSFICDGQNNCQDNSDE 144
Score = 42.7 bits (96), Expect = 0.005
Identities = 14/33 (42%), Positives = 23/33 (69%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED 55
C+++ + CK G CI S+ CD + +C D+SDE+
Sbjct: 113 CSTARYHCKNGLCIDKSFICDGQNNCQDNSDEE 145
Score = 35.1 bits (77), Expect = 0.94
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 15/93 (16%)
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIG 373
C+ F C G CIP + CD DC D+ E EC K C G
Sbjct: 29 CNIPGNFMCSNGRCIPGAWQCDGLPDC-------FDKSDEKECPKAKSKCGPTFFPCASG 81
Query: 374 YYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC 406
+C +I C ++C D GS + C
Sbjct: 82 IHC-------IIGRFRCNGFEDCPD-GSDEENC 106
>AK075546-1|BAC11689.1| 345|Homo sapiens protein ( Homo sapiens
cDNA PSEC0246 fis, clone NT2RP3001359, weakly similar to
LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2
PRECURSOR. ).
Length = 345
Score = 101 bits (243), Expect = 7e-21
Identities = 48/120 (40%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 28 FRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
F C GRCIP +W+CD DC D SDE C K C F C S CI +RC+
Sbjct: 35 FMCSNGRCIPGAWQCDGLPDCFDKSDEKE--CPKAKSKCGPTFFPCASGIHCIIGRFRCN 92
Query: 88 ATADCPDGSDEHQCEVE--ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNET 145
DCPDGSDE C C + C K G C+ +++CD +C D SDE++C +
Sbjct: 93 GFEDCPDGSDEENCTANPLLCSTARYHC--KNGLCIDKSFICDGQNNCQDNSDEESCESS 150
Score = 81.4 bits (192), Expect = 1e-14
Identities = 44/127 (34%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 182 TPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
T C +F C++G+CI W CDG DC D SDE C PK +S C T F C I
Sbjct: 26 TNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKEC---PKAKSKCGPTFFPCASGI 82
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGN-VTCRLDQFQCKDHSCIPGALYCNGVKDCPD 300
C+ + E E C N + C ++ CK+ CI + C+G +C D
Sbjct: 83 HCIIGRFRCNGFEDCPDGSDE--ENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQD 140
Query: 301 GSDEYNC 307
SDE +C
Sbjct: 141 NSDEESC 147
Score = 73.7 bits (173), Expect = 2e-12
Identities = 44/136 (32%), Positives = 58/136 (42%), Gaps = 11/136 (8%)
Query: 93 PDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNET---CRSD 149
P + ++C + P F C G C+P W CD PDC D SDEK C + C
Sbjct: 21 PGNNFTNECNI----PGNFMCSN--GRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPT 74
Query: 150 EFTCGNG-KCIQMRWVXXXXXXXXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAWWHCDG 207
F C +G CI R+ E C P + + C +G CI + CDG
Sbjct: 75 FFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDG 134
Query: 208 DVDCADGSDEVGCVST 223
+C D SDE C S+
Sbjct: 135 QNNCQDNSDEESCESS 150
Score = 67.3 bits (157), Expect = 2e-10
Identities = 39/117 (33%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 231 ISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDH-SCIPGA 289
I F C++ C+ AW E E + C F C CI G
Sbjct: 31 IPGNFMCSNG-RCIPGAWQCDGLPDCFDKSDEK-ECPKAKSKCGPTFFPCASGIHCIIGR 88
Query: 290 LYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
CNG +DCPDGSDE NCT +C + C G+CI S +CD +C + DE
Sbjct: 89 FRCNGFEDCPDGSDEENCTANPLLC-STARYHCKNGLCIDKSFICDGQNNCQDNSDE 144
Score = 42.7 bits (96), Expect = 0.005
Identities = 14/33 (42%), Positives = 23/33 (69%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDED 55
C+++ + CK G CI S+ CD + +C D+SDE+
Sbjct: 113 CSTARYHCKNGLCIDKSFICDGQNNCQDNSDEE 145
Score = 35.1 bits (77), Expect = 0.94
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 15/93 (16%)
Query: 314 CDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIG 373
C+ F C G CIP + CD DC D+ E EC K C G
Sbjct: 29 CNIPGNFMCSNGRCIPGAWQCDGLPDC-------FDKSDEKECPKAKSKCGPTFFPCASG 81
Query: 374 YYCDCEKGYKLIDNRTCEDIDECADPGSCSQIC 406
+C +I C ++C D GS + C
Sbjct: 82 IHC-------IIGRFRCNGFEDCPD-GSDEENC 106
>AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein.
Length = 223
Score = 101 bits (243), Expect = 7e-21
Identities = 70/225 (31%), Positives = 110/225 (48%), Gaps = 17/225 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
+ C++ N C +C C CE G+++ D R+C+D DECA G+CSQ C N G+
Sbjct: 3 SNCQQLN--CQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGS 60
Query: 413 FKCECHTGYARDPRDRTRCKA----TEGHPSLLFARKHDIRKISLDHHEMVAI--VNDTK 466
+ C C GY P +R+ CKA T+ P LL A I L+ +M + VN +
Sbjct: 61 YTCSCVEGYLMQPDNRS-CKAKIEPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNE 119
Query: 467 SATALDYVFRTGMIFW----SDVNDEKIYKAPIDEG--TQRTVVIGEQLITSDGLAVDWV 520
T LD+++ MI W N K + G + T+ I + +A+DW+
Sbjct: 120 IHT-LDFIYNEDMICWIESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWL 178
Query: 521 YNHLYWTDTGHNHIELSDLQGNMRKILIRDRLEEPRAIALNPLEG 565
+LY+ D + I + + G++ LI L P+AIA++P+ G
Sbjct: 179 TRNLYFVDHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAG 223
>BC030532-1|AAH30532.1| 855|Homo sapiens suppression of
tumorigenicity 14 (colon carcinoma) protein.
Length = 855
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 444 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 496
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 497 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 551
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 552 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 493 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 544
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 545 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 604
Query: 145 TCRS 148
RS
Sbjct: 605 GLRS 608
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 407 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 465 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 516
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 517 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 570
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 571 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 605
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 456 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 510
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 511 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 544
>BC018146-1|AAH18146.1| 422|Homo sapiens ST14 protein protein.
Length = 422
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 11 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 63
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 64 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 118
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 119 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 147
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 60 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 111
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 112 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 171
Query: 145 TCRS 148
RS
Sbjct: 172 GLRS 175
Score = 82.2 bits (194), Expect = 6e-15
Identities = 51/164 (31%), Positives = 70/164 (42%), Gaps = 17/164 (10%)
Query: 191 FSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVX 250
F+C G+CI CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 24 FTCRTGRCIRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVC 75
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E +C F+C + C+ + CNG DC DGSDE +C +
Sbjct: 76 DSVNDCGDNSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKV 129
Query: 311 KTI-CDKRTEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
+ C K T + C G+C+ + CD DC + DE CG
Sbjct: 130 NVVTCTKHT-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 172
Score = 79.0 bits (186), Expect = 6e-14
Identities = 47/131 (35%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXX 167
P +FTCR G C+ CD DC+D SDE C+ +FTC N C + WV
Sbjct: 21 PGQFTCR--TGRCIRKELRCDGWADCTDHSDELNCSCDA-GHQFTCKNKFCKPLFWVCDS 77
Query: 168 XXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVR 227
E C +C Q+ F C++G+C+S C+G DC DGSDE C PKV
Sbjct: 78 VNDCGDNSDEQGC---SCPAQT-FRCSNGKCLSKSQQCNGKDDCGDGSDEASC---PKVN 130
Query: 228 -SPCISTEFEC 237
C + C
Sbjct: 131 VVTCTKHTYRC 141
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 23 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 77
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 78 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 111
>BC005826-1|AAH05826.2| 526|Homo sapiens ST14 protein protein.
Length = 526
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 115 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 167
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 168 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 222
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 223 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 251
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 164 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 215
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 216 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 275
Query: 145 TCRS 148
RS
Sbjct: 276 GLRS 279
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 78 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 135
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 136 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 187
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 188 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 241
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 242 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 276
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 127 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 181
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 182 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 215
>AF283256-1|AAG13949.1| 325|Homo sapiens serine protease SNC19
protein.
Length = 325
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 105 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 157
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 158 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 212
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 213 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 241
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 154 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 205
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 206 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 265
Query: 145 TCRS 148
RS
Sbjct: 266 GLRS 269
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 68 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 125
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 126 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 177
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 178 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 231
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 232 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 266
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 117 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 171
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 172 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 205
>AF133086-1|AAF00109.1| 855|Homo sapiens membrane-type serine
protease 1 protein.
Length = 855
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 444 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 496
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 497 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 551
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 552 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 493 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 544
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 545 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 604
Query: 145 TCRS 148
RS
Sbjct: 605 GLRS 608
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 407 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 465 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 516
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 517 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 570
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 571 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 605
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 456 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 510
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 511 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 544
>AF118224-1|AAD42765.2| 855|Homo sapiens matriptase protein.
Length = 855
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 444 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 496
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 497 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 551
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 552 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 493 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 544
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 545 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 604
Query: 145 TCRS 148
RS
Sbjct: 605 GLRS 608
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 407 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 465 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 516
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 517 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 570
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 571 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 605
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 456 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 510
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 511 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 544
>AF057145-1|AAG15395.1| 855|Homo sapiens serine protease TADG15
protein.
Length = 855
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 444 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 496
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 497 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 551
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 552 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 493 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 544
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 545 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 604
Query: 145 TCRS 148
RS
Sbjct: 605 GLRS 608
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 407 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 465 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 516
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 517 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 570
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 571 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 605
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 456 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 510
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 511 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 544
>AB030036-1|BAB20376.1| 855|Homo sapiens prostamin protein.
Length = 855
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/149 (35%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 15 FLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECL 74
+L +S +F C+TGRCI +CD DC+D SDE C A ++F C
Sbjct: 444 YLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDA------GHQFTC- 496
Query: 75 SDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+ C P W CD+ DC D SDE C +C + F C G+C+ + C+ DC
Sbjct: 497 KNKFCKPLFWVCDSVNDCGDNSDEQGC---SCPAQTFRCSN--GKCLSKSQQCNGKDDCG 551
Query: 135 DGSDEKACNE----TCRSDEFTCGNGKCI 159
DGSDE +C + TC + C NG C+
Sbjct: 552 DGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Score = 88.6 bits (210), Expect = 7e-17
Identities = 50/124 (40%), Positives = 62/124 (50%), Gaps = 10/124 (8%)
Query: 27 EFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRC 86
+F CK C PL W CD+ DC D+SDE C A C S+G C+ +S +C
Sbjct: 493 QFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRC--------SNGKCLSKSQQC 544
Query: 87 DATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWMCDDNPDCSDGSDEKACNE 144
+ DC DGSDE C +V + T R G C+ CD DCSDGSDEK C+
Sbjct: 545 NGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDC 604
Query: 145 TCRS 148
RS
Sbjct: 605 GLRS 608
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 19/216 (8%)
Query: 139 EKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQC 198
EK C E RS N I +R+ E + F+C G+C
Sbjct: 407 EKYCGE--RSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRC 464
Query: 199 ISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXX 258
I CDG DC D SDE+ C S +F C ++ C WV
Sbjct: 465 IRKELRCDGWADCTDHSDELNC-------SCDAGHQFTCKNKF-CKPLFWVCDSVNDCGD 516
Query: 259 XXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTI-CDKR 317
E +C F+C + C+ + CNG DC DGSDE +C + + C K
Sbjct: 517 NSDEQ------GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKH 570
Query: 318 TEFDCGGGMCIPL-SKVCDKHVDCPNFEDEPRDRCG 352
T + C G+C+ + CD DC + DE CG
Sbjct: 571 T-YRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCG 605
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 277 QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
QF C+ CI L C+G DC D SDE NC+ CD +F C C PL VCD
Sbjct: 456 QFTCRTGRCIRKELRCDGWADCTDHSDELNCS-----CDAGHQFTCKNKFCKPLFWVCDS 510
Query: 337 HVDCPNFEDEPRDRCGENECEKNNGGC---SQRC 367
DC + DE C +NG C SQ+C
Sbjct: 511 VNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQC 544
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 96.7 bits (230), Expect = 3e-19
Identities = 82/262 (31%), Positives = 111/262 (42%), Gaps = 42/262 (16%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD C D G + CV+ C S F +++ TC+HR+
Sbjct: 101 TCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRS 160
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------D 300
E +G V C C PG KDC +
Sbjct: 161 NEGMNCMNKDHGCAHICRETPKGGVAC----------DCRPGFDLAQNQKDCTLTCNYGN 210
Query: 301 GSDEYNCTRQKTI----CDKRTEFDCGGGMCIPLSKV----CDK---------HVDCP-N 342
G +++C T C ++ G CI V CD+ CP
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVG 270
Query: 343 FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADP 399
F +P + C + NEC NNGGC C +T + C C KGYKL+ D RTC+DIDEC+
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE 330
Query: 400 GSCSQICINEKGTFKCECHTGY 421
+C ICIN G+F+C CH GY
Sbjct: 331 RTCDHICINSPGSFQCLCHRGY 352
Score = 81.4 bits (192), Expect = 1e-14
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Query: 341 PNFEDEPRDRCGENECEKN--NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P ++ E + +ECE + NGGC C++ P Y C C G+ L D C D+DEC
Sbjct: 63 PGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQ 122
Query: 398 D-PGSCSQICINEKGTFKCECHTGY 421
D G C QIC+N G+++C+CH+G+
Sbjct: 123 DNNGGCQQICVNAMGSYECQCHSGF 147
Score = 74.5 bits (175), Expect = 1e-12
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC + C DT G C C G+ L D +TC+DI+EC + G C C N G+F
Sbjct: 245 CAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSF 304
Query: 414 KCECHTGYARDPRDRT 429
+C C GY +RT
Sbjct: 305 ECGCRKGYKLLTDERT 320
Score = 62.9 bits (146), Expect = 4e-09
Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTG 420
C C+++P + C C +GY L C D+DEC+ GSC Q C+N KG+++C C G
Sbjct: 333 CDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 60.1 bits (139), Expect = 3e-08
Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 339 DC-PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC 396
DC P F+ + C NGGC C DT G C C + Y L D RTC I+ C
Sbjct: 188 DCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETC 245
Query: 397 A-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
A + G C + C + +C C G+ P +T CK
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKT-CK 281
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP---GSCSQICIN 408
+EC + C C +TP Y C C+ GYK + + CEDIDEC + G C CIN
Sbjct: 35 DECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVHECIN 93
Query: 409 EKGTFKCECHTGY 421
G ++C C G+
Sbjct: 94 IPGNYRCTCFDGF 106
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC-----EDIDECADPGSCSQIC- 406
+EC+ NNGGC Q CV+ Y C C G+ L DN+ TC E ++ C+ IC
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICR 178
Query: 407 INEKGTFKCECHTGY--ARDPRDRT 429
KG C+C G+ A++ +D T
Sbjct: 179 ETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 10/84 (11%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-------- 400
CG+ +EC +NG C Q CV+T Y C C G +L N + C + +C
Sbjct: 360 CGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQL 419
Query: 401 SCSQICINEKGTFKCECHTGYARD 424
SCS+ E C HT + D
Sbjct: 420 SCSKAGGVESCFLSCPAHTLFVPD 443
Score = 35.1 bits (77), Expect = 0.94
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 698 QPDG-----VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
QPDG +N C NG C H C R S C C G KLL D++ C + +
Sbjct: 274 QPDGKTCKDINECLVNNGGCDHFC----RNTVGS--FECGCRKGYKLLTDERTCQDIDEC 327
Query: 753 HF 754
F
Sbjct: 328 SF 329
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 96.7 bits (230), Expect = 3e-19
Identities = 82/262 (31%), Positives = 111/262 (42%), Gaps = 42/262 (16%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD C D G + CV+ C S F +++ TC+HR+
Sbjct: 101 TCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRS 160
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------D 300
E +G V C C PG KDC +
Sbjct: 161 NEGMNCMNKDHGCAHICRETPKGGVAC----------DCRPGFDLAQNQKDCTLTCNYGN 210
Query: 301 GSDEYNCTRQKTI----CDKRTEFDCGGGMCIPLSKV----CDK---------HVDCP-N 342
G +++C T C ++ G CI V CD+ CP
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVG 270
Query: 343 FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADP 399
F +P + C + NEC NNGGC C +T + C C KGYKL+ D RTC+DIDEC+
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE 330
Query: 400 GSCSQICINEKGTFKCECHTGY 421
+C ICIN G+F+C CH GY
Sbjct: 331 RTCDHICINSPGSFQCLCHRGY 352
Score = 81.4 bits (192), Expect = 1e-14
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Query: 341 PNFEDEPRDRCGENECEKN--NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P ++ E + +ECE + NGGC C++ P Y C C G+ L D C D+DEC
Sbjct: 63 PGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQ 122
Query: 398 D-PGSCSQICINEKGTFKCECHTGY 421
D G C QIC+N G+++C+CH+G+
Sbjct: 123 DNNGGCQQICVNAMGSYECQCHSGF 147
Score = 74.5 bits (175), Expect = 1e-12
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC + C DT G C C G+ L D +TC+DI+EC + G C C N G+F
Sbjct: 245 CAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSF 304
Query: 414 KCECHTGYARDPRDRT 429
+C C GY +RT
Sbjct: 305 ECGCRKGYKLLTDERT 320
Score = 62.9 bits (146), Expect = 4e-09
Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTG 420
C C+++P + C C +GY L C D+DEC+ GSC Q C+N KG+++C C G
Sbjct: 333 CDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 60.1 bits (139), Expect = 3e-08
Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 339 DC-PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC 396
DC P F+ + C NGGC C DT G C C + Y L D RTC I+ C
Sbjct: 188 DCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETC 245
Query: 397 A-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
A + G C + C + +C C G+ P +T CK
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKT-CK 281
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP---GSCSQICIN 408
+EC + C C +TP Y C C+ GYK + + CEDIDEC + G C CIN
Sbjct: 35 DECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVHECIN 93
Query: 409 EKGTFKCECHTGY 421
G ++C C G+
Sbjct: 94 IPGNYRCTCFDGF 106
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC-----EDIDECADPGSCSQIC- 406
+EC+ NNGGC Q CV+ Y C C G+ L DN+ TC E ++ C+ IC
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICR 178
Query: 407 INEKGTFKCECHTGY--ARDPRDRT 429
KG C+C G+ A++ +D T
Sbjct: 179 ETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 42.7 bits (96), Expect = 0.005
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 10/84 (11%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-------- 400
CG+ +EC +NG C Q CV+T Y C C G +L N + C + +C
Sbjct: 360 CGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQL 419
Query: 401 SCSQICINEKGTFKCECHTGYARD 424
SCS+ E C HT + D
Sbjct: 420 SCSKAGGVESCFLSCPAHTLFVPD 443
Score = 35.1 bits (77), Expect = 0.94
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 698 QPDG-----VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
QPDG +N C NG C H C R S C C G KLL D++ C + +
Sbjct: 274 QPDGKTCKDINECLVNNGGCDHFC----RNTVGS--FECGCRKGYKLLTDERTCQDIDEC 327
Query: 753 HF 754
F
Sbjct: 328 SF 329
>CR457174-1|CAG33455.1| 282|Homo sapiens 8D6A protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>BC007083-1|AAH07083.1| 282|Homo sapiens CD320 molecule protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>BC000668-1|AAH00668.1| 282|Homo sapiens CD320 molecule protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>AY358420-1|AAQ88786.1| 282|Homo sapiens SGGW198 protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>AL365455-1|CAB97010.1| 282|Homo sapiens 8D6 antigen protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>AK222623-1|BAD96343.1| 282|Homo sapiens 8D6 antigen variant
protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 95.1 bits (226), Expect = 8e-19
Identities = 82/262 (31%), Positives = 111/262 (42%), Gaps = 42/262 (16%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD C D G + CV+ C S F +++ TC+HR+
Sbjct: 101 TCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRS 160
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------D 300
E +G V C C PG KDC +
Sbjct: 161 NEGMNCMNKDHGCAHICRETPKGGVAC----------DCRPGFDLAQNQKDCTLTCNYGN 210
Query: 301 GSDEYNCTRQKTI----CDKRTEFDCGGGMCIPLSKV----CDK---------HVDCP-N 342
G +++C T C ++ G CI V CD+ CP
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYAPHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVG 270
Query: 343 FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADP 399
F +P + C + NEC NNGGC C +T + C C KGYKL+ D RTC+DIDEC+
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE 330
Query: 400 GSCSQICINEKGTFKCECHTGY 421
+C ICIN G+F+C CH GY
Sbjct: 331 RTCDHICINSPGSFQCLCHRGY 352
Score = 84.2 bits (199), Expect = 2e-15
Identities = 36/86 (41%), Positives = 54/86 (62%), Gaps = 6/86 (6%)
Query: 341 PNFEDEPRDRCGE-NECEKN--NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC 396
P ++ E + +CG+ +ECE + NGGC C++ P Y C C G+ L D C D+DEC
Sbjct: 63 PGYKGEGK-QCGDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDEC 121
Query: 397 AD-PGSCSQICINEKGTFKCECHTGY 421
D G C QIC+N G+++C+CH+G+
Sbjct: 122 QDNNGGCQQICVNAMGSYECQCHSGF 147
Score = 74.5 bits (175), Expect = 1e-12
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC + C DT G C C G+ L D +TC+DI+EC + G C C N G+F
Sbjct: 245 CAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSF 304
Query: 414 KCECHTGYARDPRDRT 429
+C C GY +RT
Sbjct: 305 ECGCRKGYKLLTDERT 320
Score = 62.9 bits (146), Expect = 4e-09
Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTG 420
C C+++P + C C +GY L C D+DEC+ GSC Q C+N KG+++C C G
Sbjct: 333 CDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 57.2 bits (132), Expect = 2e-07
Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 6/97 (6%)
Query: 339 DC-PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDEC 396
DC P F+ + C NGGC C DT G C C + Y D RTC I+ C
Sbjct: 188 DCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTC--IETC 245
Query: 397 A-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
A + G C + C + +C C G+ P +T CK
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKT-CK 281
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC-----EDIDECADPGSCSQIC- 406
+EC+ NNGGC Q CV+ Y C C G+ L DN+ TC E ++ C+ IC
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICR 178
Query: 407 INEKGTFKCECHTGY--ARDPRDRT 429
KG C+C G+ A++ +D T
Sbjct: 179 ETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP---GSCSQICIN 408
+EC + C C + P Y C C+ GYK + + C DIDEC + G C CIN
Sbjct: 35 DECSEGTDDCHIDAICQNAPKSYKCLCKPGYK-GEGKQCGDIDECENDYYNGGCVHECIN 93
Query: 409 EKGTFKCECHTGY 421
G ++C C G+
Sbjct: 94 IPGNYRCTCFDGF 106
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 10/84 (11%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPG-------- 400
CG+ +EC +NG C Q CV+T Y C C G +L NR C + +C
Sbjct: 360 CGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCVETGKCLSRAKTSPRAQL 419
Query: 401 SCSQICINEKGTFKCECHTGYARD 424
SCS+ E C HT + D
Sbjct: 420 SCSKAGGVESCFLSCPAHTLFVPD 443
Score = 35.1 bits (77), Expect = 0.94
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 698 QPDG-----VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
QPDG +N C NG C H C R S C C G KLL D++ C + +
Sbjct: 274 QPDGKTCKDINECLVNNGGCDHFC----RNTVGS--FECGCRKGYKLLTDERTCQDIDEC 327
Query: 753 HF 754
F
Sbjct: 328 SF 329
>AF161254-1|AAF61850.1| 282|Homo sapiens 8D6 antigen protein.
Length = 282
Score = 95.1 bits (226), Expect = 8e-19
Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 20 SRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFE-CLSDG 77
S +C ++F+C+T G C+PL+W+CD + DCSD SDE +E R E C G
Sbjct: 51 SGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE------------EECRIEPCTQKG 98
Query: 78 LCIP---RSWRCDATADCPDGSDE--HQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPD 132
C P C +DC G+D+ C AC E C +C+PLTW CD +PD
Sbjct: 99 QCPPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCT-LSDDCIPLTWRCDGHPD 157
Query: 133 CSDGSDEKAC 142
C D SDE C
Sbjct: 158 CPDSSDELGC 167
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C +F+C + GLC+P +WRCD DC DGSDE +C +E C ++ C PG P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCP--- 109
Query: 126 MCDDNPDCSDGSDEKA--CNE-TCRSDEFTCG-NGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C DCS G+D+K C+ C + E C + CI + W E+ C
Sbjct: 110 -CTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCG 168
Query: 182 TPTCQPQ 188
T P+
Sbjct: 169 TNEILPE 175
Score = 79.0 bits (186), Expect = 6e-14
Identities = 44/118 (37%), Positives = 52/118 (44%), Gaps = 5/118 (4%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN-ETCRSDEFTCGNGKCIQMRW 163
+C P +F CR G CVPLTW CD + DCSDGSDE+ C E C + + C +
Sbjct: 53 SCPPTKFQCRTS-GLCVPLTWRCDRDLDCSDGSDEEECRIEPC-TQKGQCPPPPGLPCPC 110
Query: 164 VXXXXXXXXXXXXEVKCPTPTCQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGC 220
C C CT CI W CDG DC D SDE+GC
Sbjct: 111 TGVSDCSGGTDKKLRNCSRLACLA-GELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC 167
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 181 PTPTCQPQSHFSC-TDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFEC-- 237
P+ P + F C T G C+ W CD D+DC+DGSDE C ++ PC + + +C
Sbjct: 49 PSSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEEC----RI-EPC-TQKGQCPP 102
Query: 238 NDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCK-DHSCIPGALYCNGVK 296
+ C + L C + C + +C CIP C+G
Sbjct: 103 PPGLPC-----PCTGVSDCSGGTDKKLRNC-SRLACLAGELRCTLSDDCIPLTWRCDGHP 156
Query: 297 DCPDGSDEYNC 307
DCPD SDE C
Sbjct: 157 DCPDSSDELGC 167
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 33 GRCIP---LSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDAT 89
G+C P L C DCS +D+ C+ ++ C C CIP +WRCD
Sbjct: 98 GQCPPPPGLPCPCTGVSDCSGGTDKKLRNCS--RLACLAGELRCTLSDDCIPLTWRCDGH 155
Query: 90 ADCPDGSDEHQCEVEACGPE-EFTCRGKP 117
DCPD SDE C PE + T G P
Sbjct: 156 PDCPDSSDELGCGTNEILPEGDATTMGPP 184
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 230 CISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA 289
C T+F+C CV W E E CR + + QC +P
Sbjct: 54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDE--EECR--IEPCTQKGQCPPPPGLPCP 109
Query: 290 LYCNGVKDCPDGSDEY--NCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDE 346
C GV DC G+D+ NC+R + E C CIPL+ CD H DCP+ DE
Sbjct: 110 --CTGVSDCSGGTDKKLRNCSRLACLAG---ELRCTLSDDCIPLTWRCDGHPDCPDSSDE 164
Query: 347 PRDRCGENE 355
CG NE
Sbjct: 165 L--GCGTNE 171
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 93.9 bits (223), Expect = 2e-18
Identities = 79/261 (30%), Positives = 110/261 (42%), Gaps = 41/261 (15%)
Query: 192 SCTDGQCISAWWHCDGDVD-CADGSD--EVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD CA+G+ + CV+ C F +++ TC+ R
Sbjct: 96 TCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRP 155
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------DG 301
E +G + C C PG +DC +G
Sbjct: 156 EGMNCMNKNHGCAHICRETPKGGIACE----------CRPGFELTKNQRDCKLTCNYGNG 205
Query: 302 SDEYNC--TRQKTICDKRTEF--DCGGGMCIPLSKV----CDK---------HVDCP-NF 343
++ C T Q C +F G CI V CD H CP F
Sbjct: 206 GCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAIGVHCTCPVGF 265
Query: 344 EDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG 400
+P R C + +EC NNGGC C +T + C C+KGYKL+ N R C+DIDEC+
Sbjct: 266 MLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDR 325
Query: 401 SCSQICINEKGTFKCECHTGY 421
+C IC+N G+F+C CH GY
Sbjct: 326 TCDHICVNTPGSFQCLCHRGY 346
Score = 74.1 bits (174), Expect = 2e-12
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 354 NECEK-NNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADP-GSCSQICINEK 410
+ECE+ +N GC CV+ P Y C C G+ L D C D+DECA+ G C Q C+N
Sbjct: 72 DECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMM 131
Query: 411 GTFKCECHTGYARDPRDRTRCKATEG 436
G+++C C G+ T + EG
Sbjct: 132 GSYECHCREGFFLSDNQHTCIQRPEG 157
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
C CV+TP + C C +GY L C D+DEC+ + G C CIN G+++C C G
Sbjct: 327 CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQ 386
Query: 422 AR---DPRDRTRCKATEGHP 438
R + +D T +G P
Sbjct: 387 GRLHWNGKDCTEPLKCQGSP 406
Score = 58.4 bits (135), Expect = 9e-08
Identities = 54/179 (30%), Positives = 75/179 (41%), Gaps = 20/179 (11%)
Query: 265 ELCRGNVTCRLD---QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD 321
E G C +D Q + + CI + Y K C D DE C R+ + D
Sbjct: 32 ECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKD-VDE--CERED---NAGCVHD 85
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C + IP + C + D + + + +EC + NGGC Q CV+ Y C C +G
Sbjct: 86 C---VNIPGNYRCTCY-DGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Query: 382 YKLIDNR-TCEDIDE---CADPG-SCSQIC-INEKGTFKCECHTGYARDPRDRTRCKAT 434
+ L DN+ TC E C + C+ IC KG CEC G+ R CK T
Sbjct: 142 FFLSDNQHTCIQRPEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD-CKLT 199
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-D 398
P FE R + C NGGC C DT G C C + L D +TC I+ CA +
Sbjct: 185 PGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVN 242
Query: 399 PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G C C + C C G+ P DR CK
Sbjct: 243 NGGCDSKCHDAAIGVHCTCPVGFMLQP-DRKTCK 275
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDEC-ADPG-SCSQI 405
CG+ +EC N GGC C++TP Y C C G + + + C + +C PG S + +
Sbjct: 354 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAML 413
Query: 406 CINEKG 411
N G
Sbjct: 414 SCNRSG 419
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 92.7 bits (220), Expect = 4e-18
Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 4/89 (4%)
Query: 337 HVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H CP F +P R C + +EC NNGGC C +T + C C+KGYKL+ N R C+D
Sbjct: 259 HCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Query: 393 IDECADPGSCSQICINEKGTFKCECHTGY 421
IDEC+ +C IC+N G+F+C CH GY
Sbjct: 319 IDECSFDRTCDHICVNTPGSFQCLCHRGY 347
Score = 77.0 bits (181), Expect = 2e-13
Identities = 32/68 (47%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC +C D G +C C G+ L D +TC+DIDEC + G C IC N G+F
Sbjct: 240 CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSF 299
Query: 414 KCECHTGY 421
+C C GY
Sbjct: 300 ECSCKKGY 307
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
C CV+TP + C C +GY L C D+DEC+ + G C CIN G+++C C G
Sbjct: 328 CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQ 387
Query: 422 AR---DPRDRTRCKATEGHP 438
R + +D T +G P
Sbjct: 388 GRLHWNGKDCTEPLKCQGSP 407
Score = 58.4 bits (135), Expect = 9e-08
Identities = 54/180 (30%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 265 ELCRGNVTCRLD---QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD 321
E G C +D Q + + CI + Y K C D DE C R+ + D
Sbjct: 32 ECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKD-VDE--CERED---NAGCVHD 85
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C + IP + C + D + + + +EC + NGGC Q CV+ Y C C +G
Sbjct: 86 C---VNIPGNYRCTCY-DGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Query: 382 YKLIDNR-TC----EDIDECADPG-SCSQIC-INEKGTFKCECHTGYARDPRDRTRCKAT 434
+ L DN+ TC E+ C + C+ IC KG CEC G+ R CK T
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD-CKLT 200
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-D 398
P FE R + C NGGC C DT G C C + L D +TC I+ CA +
Sbjct: 186 PGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVN 243
Query: 399 PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G C C + C C G+ P DR CK
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQP-DRKTCK 276
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDEC-ADPG-SCSQI 405
CG+ +EC N GGC C++TP Y C C G + + + C + +C PG S + +
Sbjct: 355 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAML 414
Query: 406 CINEKG 411
N G
Sbjct: 415 SCNRSG 420
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 92.7 bits (220), Expect = 4e-18
Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 4/89 (4%)
Query: 337 HVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H CP F +P R C + +EC NNGGC C +T + C C+KGYKL+ N R C+D
Sbjct: 259 HCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Query: 393 IDECADPGSCSQICINEKGTFKCECHTGY 421
IDEC+ +C IC+N G+F+C CH GY
Sbjct: 319 IDECSFDRTCDHICVNTPGSFQCLCHRGY 347
Score = 77.0 bits (181), Expect = 2e-13
Identities = 32/68 (47%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC +C D G +C C G+ L D +TC+DIDEC + G C IC N G+F
Sbjct: 240 CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSF 299
Query: 414 KCECHTGY 421
+C C GY
Sbjct: 300 ECSCKKGY 307
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
C CV+TP + C C +GY L C D+DEC+ + G C CIN G+++C C G
Sbjct: 328 CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQ 387
Query: 422 AR---DPRDRTRCKATEGHP 438
R + +D T +G P
Sbjct: 388 GRLHWNGKDCTEPLKCQGSP 407
Score = 58.4 bits (135), Expect = 9e-08
Identities = 54/180 (30%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 265 ELCRGNVTCRLD---QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD 321
E G C +D Q + + CI + Y K C D DE C R+ + D
Sbjct: 32 ECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKD-VDE--CERED---NAGCVHD 85
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C + IP + C + D + + + +EC + NGGC Q CV+ Y C C +G
Sbjct: 86 C---VNIPGNYRCTCY-DGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Query: 382 YKLIDNR-TC----EDIDECADPG-SCSQIC-INEKGTFKCECHTGYARDPRDRTRCKAT 434
+ L DN+ TC E+ C + C+ IC KG CEC G+ R CK T
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD-CKLT 200
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-D 398
P FE R + C NGGC C DT G C C + L D +TC I+ CA +
Sbjct: 186 PGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVN 243
Query: 399 PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G C C + C C G+ P DR CK
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQP-DRKTCK 276
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDEC-ADPG-SCSQI 405
CG+ +EC N GGC C++TP Y C C G + + + C + +C PG S + +
Sbjct: 355 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAML 414
Query: 406 CINEKG 411
N G
Sbjct: 415 SCNRSG 420
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 92.7 bits (220), Expect = 4e-18
Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 4/89 (4%)
Query: 337 HVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H CP F +P R C + +EC NNGGC C +T + C C+KGYKL+ N R C+D
Sbjct: 146 HCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 205
Query: 393 IDECADPGSCSQICINEKGTFKCECHTGY 421
IDEC+ +C IC+N G+F+C CH GY
Sbjct: 206 IDECSFDRTCDHICVNTPGSFQCLCHRGY 234
Score = 78.6 bits (185), Expect = 8e-14
Identities = 47/140 (33%), Positives = 60/140 (42%), Gaps = 3/140 (2%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFE 344
C PG +DC + N Q T D CG + L + E
Sbjct: 55 CRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIGERRLE 114
Query: 345 DEPRDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGS 401
+ NE C NNGGC +C D G +C C G+ L D +TC+DIDEC + G
Sbjct: 115 QHIPTQAVSNETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGG 174
Query: 402 CSQICINEKGTFKCECHTGY 421
C IC N G+F+C C GY
Sbjct: 175 CDHICRNTVGSFECSCKKGY 194
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
C CV+TP + C C +GY L C D+DEC+ + G C CIN G+++C C G
Sbjct: 215 CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQ 274
Query: 422 AR---DPRDRTRCKATEGHP 438
R + +D T +G P
Sbjct: 275 GRLHWNGKDCTEPLKCQGSP 294
Score = 41.1 bits (92), Expect = 0.014
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 356 CEKNNGGCSQRCVDTPI-GYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQICINEKGTF 413
C N GC+ C +TP G C+C G++L N R C+ + G C C + +
Sbjct: 32 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGN-GGCQHTCDDTEQGP 90
Query: 414 KCECH 418
+C CH
Sbjct: 91 RCGCH 95
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDEC-ADPG-SCSQI 405
CG+ +EC N GGC C++TP Y C C G + + + C + +C PG S + +
Sbjct: 242 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAML 301
Query: 406 CINEKG 411
N G
Sbjct: 302 SCNRSG 307
Score = 36.3 bits (80), Expect = 0.41
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 374 YYCDCEKGYKLIDNR-TC----EDIDECADPG-SCSQIC-INEKGTFKCECHTGYARDPR 426
Y C C +G+ L DN+ TC E+ C + C+ IC KG CEC G+
Sbjct: 5 YECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKN 64
Query: 427 DRTRCKAT 434
R CK T
Sbjct: 65 QRD-CKLT 71
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 92.7 bits (220), Expect = 4e-18
Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 4/89 (4%)
Query: 337 HVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H CP F +P R C + +EC NNGGC C +T + C C+KGYKL+ N R C+D
Sbjct: 259 HCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Query: 393 IDECADPGSCSQICINEKGTFKCECHTGY 421
IDEC+ +C IC+N G+F+C CH GY
Sbjct: 319 IDECSFDRTCDHICVNTPGSFQCLCHRGY 347
Score = 77.0 bits (181), Expect = 2e-13
Identities = 32/68 (47%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTF 413
C NNGGC +C D G +C C G+ L D +TC+DIDEC + G C IC N G+F
Sbjct: 240 CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSF 299
Query: 414 KCECHTGY 421
+C C GY
Sbjct: 300 ECSCKKGY 307
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
C CV+TP + C C +GY L C D+DEC+ + G C CIN G+++C C G
Sbjct: 328 CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQ 387
Query: 422 AR---DPRDRTRCKATEGHP 438
R + +D T +G P
Sbjct: 388 GRLHWNGKDCTEPLKCQGSP 407
Score = 58.4 bits (135), Expect = 9e-08
Identities = 54/180 (30%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 265 ELCRGNVTCRLD---QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD 321
E G C +D Q + + CI + Y K C D DE C R+ + D
Sbjct: 32 ECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKD-VDE--CERED---NAGCVHD 85
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
C + IP + C + D + + + +EC + NGGC Q CV+ Y C C +G
Sbjct: 86 C---VNIPGNYRCTCY-DGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREG 141
Query: 382 YKLIDNR-TC----EDIDECADPG-SCSQIC-INEKGTFKCECHTGYARDPRDRTRCKAT 434
+ L DN+ TC E+ C + C+ IC KG CEC G+ R CK T
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRD-CKLT 200
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-D 398
P FE R + C NGGC C DT G C C + L D +TC I+ CA +
Sbjct: 186 PGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVN 243
Query: 399 PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G C C + C C G+ P DR CK
Sbjct: 244 NGGCDSKCHDAATGVHCTCPVGFMLQP-DRKTCK 276
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDEC-ADPG-SCSQI 405
CG+ +EC N GGC C++TP Y C C G + + + C + +C PG S + +
Sbjct: 355 CGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAML 414
Query: 406 CINEKG 411
N G
Sbjct: 415 SCNRSG 420
>CR456446-1|CAG30332.1| 824|Homo sapiens dJ1170K4.2 protein.
Length = 824
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 436 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 485
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 486 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 541
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 542 CDGRPDCRDGSDEEHCD 558
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 504
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 505 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 536
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 500
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 501 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 452 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 501
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 502 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 538
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 476 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 531
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 532 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 564
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 450 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 502
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 503 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 479 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 535
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 536 KKPNPQCDGRPDCRDGSDEEHCDCG 560
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 480 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 534
Query: 244 VHR 246
V +
Sbjct: 535 VKK 537
>AY358398-1|AAQ88764.1| 802|Homo sapiens PVAE354 protein.
Length = 802
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 436 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 485
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 486 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 541
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 542 CDGRPDCRDGSDEEHCD 558
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 504
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 505 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 536
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 500
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 501 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 452 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 501
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 502 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 538
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 476 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 531
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 532 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 564
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 450 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 502
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 503 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 479 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 535
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 536 KKPNPQCDGRPDCRDGSDEEHCDCG 560
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 480 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 534
Query: 244 VHR 246
V +
Sbjct: 535 VKK 537
>AY055384-1|AAL16414.1| 811|Homo sapiens type II transmembrane
serine protease 6 protein.
Length = 811
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 445 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 494
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 495 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 550
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 551 CDGRPDCRDGSDEEHCD 567
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 513
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 514 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 545
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 509
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 510 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 461 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 510
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 511 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 547
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 485 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 540
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 541 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 573
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 459 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 511
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 512 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 488 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 544
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 545 KKPNPQCDGRPDCRDGSDEEHCDCG 569
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 489 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 543
Query: 244 VHR 246
V +
Sbjct: 544 VKK 546
>AY055383-1|AAL16413.1| 811|Homo sapiens type II transmembrane
serine protease 6 protein.
Length = 811
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 445 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 494
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 495 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 550
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 551 CDGRPDCRDGSDEEHCD 567
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 513
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 514 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 545
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 509
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 510 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 461 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 510
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 511 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 547
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 485 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 540
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 541 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 573
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 459 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 511
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 512 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 488 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 544
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 545 KKPNPQCDGRPDCRDGSDEEHCDCG 569
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 489 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 543
Query: 244 VHR 246
V +
Sbjct: 544 VKK 546
>AL022314-2|CAI19335.1| 788|Homo sapiens protein ( Human DNA
sequence from clone RP5-1170K4 on chromosome
22q12.2-13.1.1. ).
Length = 788
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 422 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 471
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 472 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 527
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 528 CDGRPDCRDGSDEEHCD 544
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 439 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 490
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 491 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 522
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 439 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 486
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 487 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 543
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 438 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 487
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 488 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 524
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 462 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 517
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 518 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 550
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 436 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 488
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 489 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 543
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 465 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 521
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 522 KKPNPQCDGRPDCRDGSDEEHCDCG 546
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 466 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 520
Query: 244 VHR 246
V +
Sbjct: 521 VKK 523
>AJ319876-1|CAC85953.1| 802|Homo sapiens matriptase-2 protein.
Length = 802
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/137 (39%), Positives = 67/137 (48%), Gaps = 17/137 (12%)
Query: 10 VHIYFFLFSESRTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQE 68
V +++ L+++S C EF C G C+P CD KDC + DE VC AT
Sbjct: 436 VRVHYGLYNQSDPCPG-EFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT------ 485
Query: 69 YRFECLSDGLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL-TWM 126
F+C D CI CD DC +GSDE QC E CG F C + CV
Sbjct: 486 --FQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDR--SCVKKPNPQ 541
Query: 127 CDDNPDCSDGSDEKACN 143
CD PDC DGSDE+ C+
Sbjct: 542 CDGRPDCRDGSDEEHCD 558
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 71 FECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDN 130
F C +GLC+P CD DCP+G DE C A F C+ + C+ L +CD
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRAT----FQCK-EDSTCISLPKVCDGQ 504
Query: 131 PDCSDGSDEKACNE--TCRSDEFTCGNGKCIQ 160
PDC +GSDE+ C E C + F C + C++
Sbjct: 505 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVK 536
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 191 FSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C+ +G C+ A CDG DC +G DE CV C +T F+C + TC+ V
Sbjct: 453 FLCSVNGLCVPA---CDGVKDCPNGLDERNCV--------CRAT-FQCKEDSTCISLPKV 500
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEYNC 307
E E C+ V C FQC+D SC+ C+G DC DGSDE +C
Sbjct: 501 CDGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 277 QFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC-GGGMCIPLSKVC 334
+F C + C+P C+GVKDCP+G DE NC +C R F C CI L KVC
Sbjct: 452 EFLCSVNGLCVPA---CDGVKDCPNGLDERNC-----VC--RATFQCKEDSTCISLPKVC 501
Query: 335 DKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQR-CVDTP 371
D DC N DE ++C E C C R CV P
Sbjct: 502 DGQPDCLNGSDE--EQCQEGVPCGTFTFQCEDRSCVKKP 538
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 19 ESRTCTS-SEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
+ R C + F+CK CI L CD + DC + SDE+ C + C + F+C D
Sbjct: 476 DERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQ--CQEG-VPCGTFTFQC-ED 531
Query: 77 GLCIPR-SWRCDATADCPDGSDEHQCEVEACGP 108
C+ + + +CD DC DGSDE C+ GP
Sbjct: 532 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP 564
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 108 PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWVXX 166
P EF C G CVP CD DC +G DE+ C CR+ F C + CI + V
Sbjct: 450 PGEFLCSVN-GLCVPA---CDGVKDCPNGLDERNC--VCRAT-FQCKEDSTCISLPKVCD 502
Query: 167 XXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWW-HCDGDVDCADGSDEVGC 220
E +C F C D C+ CDG DC DGSDE C
Sbjct: 503 GQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 557
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 270 NVTCRLDQFQCK-DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCI 328
N CR FQCK D +CI C+G DC +GSDE C ++ C T F C C+
Sbjct: 479 NCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSDEEQC-QEGVPCGTFT-FQCEDRSCV 535
Query: 329 PL-SKVCDKHVDCPNFEDEPRDRCG 352
+ CD DC + DE CG
Sbjct: 536 KKPNPQCDGRPDCRDGSDEEHCDCG 560
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 185 CQPQSHFSCT-DGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITC 243
C ++ F C D CIS CDG DC +GSDE C + PC + F+C DR +C
Sbjct: 480 CVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC----QEGVPCGTFTFQCEDR-SC 534
Query: 244 VHR 246
V +
Sbjct: 535 VKK 537
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 89.4 bits (212), Expect = 4e-17
Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGT 412
N CE NNGGCS C T G C C +GY+L D RTC D+D+CAD C Q+C N G
Sbjct: 228 NSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 287
Query: 413 FKCECHTGY 421
++C C+ GY
Sbjct: 288 YECGCYAGY 296
Score = 73.3 bits (172), Expect = 3e-12
Identities = 49/158 (31%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM--CI 328
CR C+ H C+ PG+ C +C G + +R + GG C+
Sbjct: 60 CRTHNGGCQ-HRCVNTPGSYLC----ECKPGFRLHTDSRT-CLAINSCALGNGGCQHHCV 113
Query: 329 PLSKVCDKHVDC-PNFE--DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
L+ + C P F+ ++ R + C NG C RC C+C GY+L
Sbjct: 114 QLT-ITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 172
Query: 386 -DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGY 421
D + CED+DECA C+ C+N +G+FKC CH GY
Sbjct: 173 ADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY 210
Score = 72.9 bits (171), Expect = 4e-12
Identities = 62/215 (28%), Positives = 81/215 (37%), Gaps = 10/215 (4%)
Query: 227 RSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCI 286
RSPC + C R V R + + C C QC H C+
Sbjct: 140 RSPCANRNGSCMHRCQVV-RGLARCECHVGYQLAADG-KACEDVDECAAGLAQCA-HGCL 196
Query: 287 --PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN-F 343
G+ C G+D C R + E + GG CP +
Sbjct: 197 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 256
Query: 344 E-DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP-G 400
E D + C + + ++ C Q C + P GY C C GY+L D CED+DECA G
Sbjct: 257 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRG 316
Query: 401 SCSQICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C C N G+F+C C GY R DR C E
Sbjct: 317 GCEHHCTNLAGSFQCSCEAGY-RLHEDRRGCSPLE 350
Score = 69.3 bits (162), Expect = 5e-11
Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
+EC +NGGC RCV+TP Y C+C+ G++L D+RTC I+ CA G C C+
Sbjct: 58 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 117
Query: 412 T-FKCECHTGY 421
T +C+C G+
Sbjct: 118 TRHRCQCRPGF 128
Score = 46.4 bits (105), Expect = 4e-04
Identities = 100/412 (24%), Positives = 139/412 (33%), Gaps = 62/412 (15%)
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE------EFTCRGKPG-ECVPLT 124
+C + G C+ CD CP+G C E C P+ F+C + G C +T
Sbjct: 421 DCRNGGTCLLGLDGCD----CPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVT 475
Query: 125 WMCDDNP-----DCSDGSDEKACNETCRSDEFTCGN-GKCIQMRWVXXXXXXXXXXXXEV 178
C P +C DG + + CR + C N G+C ++ +
Sbjct: 476 GACRCPPGVSGTNCEDGCPKGYYGKHCRK-KCNCANRGRCHRLYGACLCDPGLYGRFCHL 534
Query: 179 KCPT----PTCQP-----QSHF-SCT--DGQC-ISAWWHCDG-DVDCADGSDEVGC--VS 222
CP P C Q H SC DG C A + + +C G GC
Sbjct: 535 TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC 594
Query: 223 TPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQFQCK 281
T V C S EC R + C G C QC+
Sbjct: 595 TCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 654
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICD--KRTEFDCGGGMCIP--LSKVCDKH 337
C PG + DCP+G C C R + + G +C+P + C
Sbjct: 655 ---CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 711
Query: 338 VDCPNFEDEPRDRC---GENECEKNNGGCSQRCVDTPIGYYCD--CEKGYKLIDNRTCED 392
+ + RC + C G CS C G+ C C+ G+ D C
Sbjct: 712 CPAGWYGPSCQTRCSCANDGHCHPATGHCS--CAPGWTGFSCQRACDTGHWGPD---CSH 766
Query: 393 IDEC-ADPGSC---SQICINEKGTF--KCE--CHTGYARDPRDRTRCKATEG 436
C A GSC S +C+ E G +CE C G+ P RC+ G
Sbjct: 767 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHF-GPGCEQRCQCQHG 817
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 349 DRCG---ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDE 395
D CG +EC + GGC C + + C CE GY+L D R C ++E
Sbjct: 301 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 39.1 bits (87), Expect = 0.058
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 379 EKGYKLIDNRTCEDIDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ GY + D+DEC G C C+N G++ CEC G+ RT
Sbjct: 43 QAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Score = 35.9 bits (79), Expect = 0.54
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%)
Query: 702 VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVE 748
VN C A NG CSH C GP C CP G +L D + C++
Sbjct: 227 VNSCEANNGGCSHGCSHTSA-GP-----LCTCPRGYELDTDQRTCID 267
Score = 32.7 bits (71), Expect = 5.0
Identities = 23/92 (25%), Positives = 32/92 (34%), Gaps = 8/92 (8%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE---EFTCRGKPGECVP 122
CQ R C +DG C P + C S + C+ GP+ C G C
Sbjct: 721 CQT-RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 779
Query: 123 LTWMCDDNPDCSDGSDEKACNETCRSDEFTCG 154
++ +C C G C + C F G
Sbjct: 780 ISGLC----LCEAGYVGPRCEQQCPQGHFGPG 807
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 89.4 bits (212), Expect = 4e-17
Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGT 412
N CE NNGGCS C T G C C +GY+L D RTC D+D+CAD C Q+C N G
Sbjct: 228 NSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 287
Query: 413 FKCECHTGY 421
++C C+ GY
Sbjct: 288 YECGCYAGY 296
Score = 73.3 bits (172), Expect = 3e-12
Identities = 49/158 (31%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM--CI 328
CR C+ H C+ PG+ C +C G + +R + GG C+
Sbjct: 60 CRTHNGGCQ-HRCVNTPGSYLC----ECKPGFRLHTDSRT-CLAINSCALGNGGCQHHCV 113
Query: 329 PLSKVCDKHVDC-PNFE--DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
L+ + C P F+ ++ R + C NG C RC C+C GY+L
Sbjct: 114 QLT-ITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 172
Query: 386 -DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGY 421
D + CED+DECA C+ C+N +G+FKC CH GY
Sbjct: 173 ADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY 210
Score = 72.9 bits (171), Expect = 4e-12
Identities = 62/215 (28%), Positives = 81/215 (37%), Gaps = 10/215 (4%)
Query: 227 RSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCI 286
RSPC + C R V R + + C C QC H C+
Sbjct: 140 RSPCANRNGSCMHRCQVV-RGLARCECHVGYQLAADG-KACEDVDECAAGLAQCA-HGCL 196
Query: 287 --PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN-F 343
G+ C G+D C R + E + GG CP +
Sbjct: 197 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 256
Query: 344 E-DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP-G 400
E D + C + + ++ C Q C + P GY C C GY+L D CED+DECA G
Sbjct: 257 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRG 316
Query: 401 SCSQICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C C N G+F+C C GY R DR C E
Sbjct: 317 GCEHHCTNLAGSFQCSCEAGY-RLHEDRRGCSPLE 350
Score = 69.3 bits (162), Expect = 5e-11
Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
+EC +NGGC RCV+TP Y C+C+ G++L D+RTC I+ CA G C C+
Sbjct: 58 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 117
Query: 412 T-FKCECHTGY 421
T +C+C G+
Sbjct: 118 TRHRCQCRPGF 128
Score = 46.4 bits (105), Expect = 4e-04
Identities = 100/412 (24%), Positives = 139/412 (33%), Gaps = 62/412 (15%)
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE------EFTCRGKPG-ECVPLT 124
+C + G C+ CD CP+G C E C P+ F+C + G C +T
Sbjct: 421 DCRNGGTCLLGLDGCD----CPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVT 475
Query: 125 WMCDDNP-----DCSDGSDEKACNETCRSDEFTCGN-GKCIQMRWVXXXXXXXXXXXXEV 178
C P +C DG + + CR + C N G+C ++ +
Sbjct: 476 GACRCPPGVSGTNCEDGCPKGYYGKHCRK-KCNCANRGRCHRLYGACLCDPGLYGRFCHL 534
Query: 179 KCPT----PTCQP-----QSHF-SCT--DGQC-ISAWWHCDG-DVDCADGSDEVGC--VS 222
CP P C Q H SC DG C A + + +C G GC
Sbjct: 535 TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC 594
Query: 223 TPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQFQCK 281
T V C S EC R + C G C QC+
Sbjct: 595 TCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 654
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICD--KRTEFDCGGGMCIP--LSKVCDKH 337
C PG + DCP+G C C R + + G +C+P + C
Sbjct: 655 ---CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 711
Query: 338 VDCPNFEDEPRDRC---GENECEKNNGGCSQRCVDTPIGYYCD--CEKGYKLIDNRTCED 392
+ + RC + C G CS C G+ C C+ G+ D C
Sbjct: 712 CPAGWYGPSCQTRCSCANDGHCHPATGHCS--CAPGWTGFSCQRACDTGHWGPD---CSH 766
Query: 393 IDEC-ADPGSC---SQICINEKGTF--KCE--CHTGYARDPRDRTRCKATEG 436
C A GSC S +C+ E G +CE C G+ P RC+ G
Sbjct: 767 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHF-GPGCEQRCQCQHG 817
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 349 DRCG---ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDE 395
D CG +EC + GGC C + + C CE GY+L D R C ++E
Sbjct: 301 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 39.1 bits (87), Expect = 0.058
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 379 EKGYKLIDNRTCEDIDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ GY + D+DEC G C C+N G++ CEC G+ RT
Sbjct: 43 QAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 94
Score = 35.9 bits (79), Expect = 0.54
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%)
Query: 702 VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVE 748
VN C A NG CSH C GP C CP G +L D + C++
Sbjct: 227 VNSCEANNGGCSHGCSHTSA-GP-----LCTCPRGYELDTDQRTCID 267
Score = 32.7 bits (71), Expect = 5.0
Identities = 23/92 (25%), Positives = 32/92 (34%), Gaps = 8/92 (8%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE---EFTCRGKPGECVP 122
CQ R C +DG C P + C S + C+ GP+ C G C
Sbjct: 721 CQT-RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 779
Query: 123 LTWMCDDNPDCSDGSDEKACNETCRSDEFTCG 154
++ +C C G C + C F G
Sbjct: 780 ISGLC----LCEAGYVGPRCEQQCPQGHFGPG 807
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 89.4 bits (212), Expect = 4e-17
Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGT 412
N CE NNGGCS C T G C C +GY+L D RTC D+D+CAD C Q+C N G
Sbjct: 408 NSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 467
Query: 413 FKCECHTGY 421
++C C+ GY
Sbjct: 468 YECGCYAGY 476
Score = 78.2 bits (184), Expect = 1e-13
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
GG C+P S + CP PR + +EC +NGGC RCV+TP Y C+C+ G++
Sbjct: 211 GGRCVPGSA---QPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFR 267
Query: 384 L-IDNRTCEDIDECA-DPGSCSQICINEKGT-FKCECHTGY 421
L D+RTC I+ CA G C C+ T +C+C G+
Sbjct: 268 LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 308
Score = 73.3 bits (172), Expect = 3e-12
Identities = 49/158 (31%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM--CI 328
CR C+ H C+ PG+ C +C G + +R + GG C+
Sbjct: 240 CRTHNGGCQ-HRCVNTPGSYLC----ECKPGFRLHTDSRT-CLAINSCALGNGGCQHHCV 293
Query: 329 PLSKVCDKHVDC-PNFE--DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
L+ + C P F+ ++ R + C NG C RC C+C GY+L
Sbjct: 294 QLT-ITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 352
Query: 386 -DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGY 421
D + CED+DECA C+ C+N +G+FKC CH GY
Sbjct: 353 ADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY 390
Score = 72.9 bits (171), Expect = 4e-12
Identities = 62/215 (28%), Positives = 81/215 (37%), Gaps = 10/215 (4%)
Query: 227 RSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCI 286
RSPC + C R V R + + C C QC H C+
Sbjct: 320 RSPCANRNGSCMHRCQVV-RGLARCECHVGYQLAADG-KACEDVDECAAGLAQCA-HGCL 376
Query: 287 --PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN-F 343
G+ C G+D C R + E + GG CP +
Sbjct: 377 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 436
Query: 344 E-DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP-G 400
E D + C + + ++ C Q C + P GY C C GY+L D CED+DECA G
Sbjct: 437 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRG 496
Query: 401 SCSQICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C C N G+F+C C GY R DR C E
Sbjct: 497 GCEHHCTNLAGSFQCSCEAGY-RLHEDRRGCSPLE 530
Score = 46.0 bits (104), Expect = 5e-04
Identities = 98/406 (24%), Positives = 135/406 (33%), Gaps = 63/406 (15%)
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE------EFTCRGKPG-ECVPLT 124
+C + G C+ CD CP+G C E C P+ F+C + G C +T
Sbjct: 601 DCRNGGTCLLGLDGCD----CPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVT 655
Query: 125 WMCDDNP-----DCSDGSDEKACNETCRSDEFTCGN-GKCIQMRWVXXXXXXXXXXXXEV 178
C P +C DG + + CR + C N G+C ++ +
Sbjct: 656 GACRCPPGVSGTNCEDGCPKGYYGKHCRK-KCNCANRGRCHRLYGACLCDPGLYGRFCHL 714
Query: 179 KCPT----PTCQP-----QSHF-SCT--DGQC-ISAWWHCDG-DVDCADGSDEVGC--VS 222
CP P C Q H SC DG C A + + +C G GC
Sbjct: 715 TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC 774
Query: 223 TPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQFQCK 281
T V C S EC R + C G C QC+
Sbjct: 775 TCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 834
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICD--KRTEFDCGGGMCIP--LSKVCDKH 337
C PG + DCP+G C C R + + G +C+P + C
Sbjct: 835 ---CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 891
Query: 338 VDCPNFEDEPRDRC---GENECEKNNGGCSQRCVDTPIGYYCD--CEKGYKLIDNRTCED 392
+ + RC + C G CS C G+ C C+ G+ D C
Sbjct: 892 CPAGWYGPSCQTRCSCANDGHCHPATGHCS--CAPGWTGFSCQRACDTGHWGPD---CSH 946
Query: 393 IDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C A GSC I + C C GY PR +C +GH
Sbjct: 947 PCNCSAGHGSCDAI------SGLCLCEAGYV-GPRCEQQC--PQGH 983
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 5/92 (5%)
Query: 340 CPNFEDEPRDR-CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-A 397
C + +P + C EC RCV C C G++ R D+DEC
Sbjct: 186 CRGWMQQPDEEGCLSAECSAGLCFHGGRCVPGS-AQPCHCPPGFQ--GPRCQYDVDECRT 242
Query: 398 DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
G C C+N G++ CEC G+ RT
Sbjct: 243 HNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 274
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 349 DRCG---ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDE 395
D CG +EC + GGC C + + C CE GY+L D R C ++E
Sbjct: 481 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 531
Score = 38.3 bits (85), Expect = 0.10
Identities = 87/398 (21%), Positives = 123/398 (30%), Gaps = 49/398 (12%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE---EFTCRGKPGECVP 122
CQ R C +DG C P + C S + C+ GP+ C G C
Sbjct: 901 CQT-RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 959
Query: 123 LTWMCDDNPDCSDGSDEKACNETCRSDEF--------TCGNG-KCIQMRWVXXXXXXXXX 173
++ +C C G C + C F C +G C +
Sbjct: 960 ISGLC----LCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRG 1015
Query: 174 XXXEVKCPTP--TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCI 231
E CP +S +CT G A +G C G C T P
Sbjct: 1016 TFCEHACPAGFFGLDCRSACNCTAGAACDA---VNGSCLCPAGRRGPRCAET----CPAH 1068
Query: 232 STEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCI-PGAL 290
+ C+ C + A C L C+ HSC+
Sbjct: 1069 TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR-HSCLCQNGG 1127
Query: 291 YCNGVKD---CPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVD-CPNFEDE 346
C+ V CP+G C ++ D R GG C+ +CD H C
Sbjct: 1128 TCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGG-CLN-GGLCDPHTGRCLCPAGW 1185
Query: 347 PRDRCGENECEKNNGG--CSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGS--- 401
D+C ++ C + G C+QRC P + T ++ PGS
Sbjct: 1186 TGDKC-QSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQACPPGSFGE 1244
Query: 402 -CSQIC-------INEKGTFKCECHTGYARDPRDRTRC 431
C+Q+C T C C GY P + RC
Sbjct: 1245 DCAQMCQCPGENPACHPATGTCSCAAGY-HGPSCQQRC 1281
Score = 35.9 bits (79), Expect = 0.54
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%)
Query: 702 VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVE 748
VN C A NG CSH C GP C CP G +L D + C++
Sbjct: 407 VNSCEANNGGCSHGCSHTSA-GP-----LCTCPRGYELDTDQRTCID 447
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 89.4 bits (212), Expect = 4e-17
Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGT 412
N CE NNGGCS C T G C C +GY+L D RTC D+D+CAD C Q+C N G
Sbjct: 245 NSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 304
Query: 413 FKCECHTGY 421
++C C+ GY
Sbjct: 305 YECGCYAGY 313
Score = 73.3 bits (172), Expect = 3e-12
Identities = 49/158 (31%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM--CI 328
CR C+ H C+ PG+ C +C G + +R + GG C+
Sbjct: 77 CRTHNGGCQ-HRCVNTPGSYLC----ECKPGFRLHTDSRT-CLAINSCALGNGGCQHHCV 130
Query: 329 PLSKVCDKHVDC-PNFE--DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
L+ + C P F+ ++ R + C NG C RC C+C GY+L
Sbjct: 131 QLT-ITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 189
Query: 386 -DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGY 421
D + CED+DECA C+ C+N +G+FKC CH GY
Sbjct: 190 ADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY 227
Score = 72.9 bits (171), Expect = 4e-12
Identities = 62/215 (28%), Positives = 81/215 (37%), Gaps = 10/215 (4%)
Query: 227 RSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCI 286
RSPC + C R V R + + C C QC H C+
Sbjct: 157 RSPCANRNGSCMHRCQVV-RGLARCECHVGYQLAADG-KACEDVDECAAGLAQCA-HGCL 213
Query: 287 --PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN-F 343
G+ C G+D C R + E + GG CP +
Sbjct: 214 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 273
Query: 344 E-DEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP-G 400
E D + C + + ++ C Q C + P GY C C GY+L D CED+DECA G
Sbjct: 274 ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRG 333
Query: 401 SCSQICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C C N G+F+C C GY R DR C E
Sbjct: 334 GCEHHCTNLAGSFQCSCEAGY-RLHEDRRGCSPLE 367
Score = 69.3 bits (162), Expect = 5e-11
Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
+EC +NGGC RCV+TP Y C+C+ G++L D+RTC I+ CA G C C+
Sbjct: 75 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 134
Query: 412 T-FKCECHTGY 421
T +C+C G+
Sbjct: 135 TRHRCQCRPGF 145
Score = 46.0 bits (104), Expect = 5e-04
Identities = 98/406 (24%), Positives = 135/406 (33%), Gaps = 63/406 (15%)
Query: 72 ECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE------EFTCRGKPG-ECVPLT 124
+C + G C+ CD CP+G C E C P+ F+C + G C +T
Sbjct: 438 DCRNGGTCLLGLDGCD----CPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVT 492
Query: 125 WMCDDNP-----DCSDGSDEKACNETCRSDEFTCGN-GKCIQMRWVXXXXXXXXXXXXEV 178
C P +C DG + + CR + C N G+C ++ +
Sbjct: 493 GACRCPPGVSGTNCEDGCPKGYYGKHCRK-KCNCANRGRCHRLYGACLCDPGLYGRFCHL 551
Query: 179 KCPT----PTCQP-----QSHF-SCT--DGQC-ISAWWHCDG-DVDCADGSDEVGC--VS 222
CP P C Q H SC DG C A + + +C G GC
Sbjct: 552 TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC 611
Query: 223 TPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQFQCK 281
T V C S EC R + C G C QC+
Sbjct: 612 TCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 671
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICD--KRTEFDCGGGMCIP--LSKVCDKH 337
C PG + DCP+G C C R + + G +C+P + C
Sbjct: 672 ---CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 728
Query: 338 VDCPNFEDEPRDRC---GENECEKNNGGCSQRCVDTPIGYYCD--CEKGYKLIDNRTCED 392
+ + RC + C G CS C G+ C C+ G+ D C
Sbjct: 729 CPAGWYGPSCQTRCSCANDGHCHPATGHCS--CAPGWTGFSCQRACDTGHWGPD---CSH 783
Query: 393 IDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
C A GSC I + C C GY PR +C +GH
Sbjct: 784 PCNCSAGHGSCDAI------SGLCLCEAGYV-GPRCEQQC--PQGH 820
Score = 43.2 bits (97), Expect = 0.004
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 349 DRCG---ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDE 395
D CG +EC + GGC C + + C CE GY+L D R C ++E
Sbjct: 318 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 368
Score = 39.1 bits (87), Expect = 0.058
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 379 EKGYKLIDNRTCEDIDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ GY + D+DEC G C C+N G++ CEC G+ RT
Sbjct: 60 QAGYPVSAGDQRPDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 111
Score = 35.9 bits (79), Expect = 0.54
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%)
Query: 702 VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVE 748
VN C A NG CSH C GP C CP G +L D + C++
Sbjct: 244 VNSCEANNGGCSHGCSHTSA-GP-----LCTCPRGYELDTDQRTCID 284
Score = 32.7 bits (71), Expect = 5.0
Identities = 23/92 (25%), Positives = 32/92 (34%), Gaps = 8/92 (8%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPE---EFTCRGKPGECVP 122
CQ R C +DG C P + C S + C+ GP+ C G C
Sbjct: 738 CQT-RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 796
Query: 123 LTWMCDDNPDCSDGSDEKACNETCRSDEFTCG 154
++ +C C G C + C F G
Sbjct: 797 ISGLC----LCEAGYVGPRCEQQCPQGHFGPG 824
>BC032109-1|AAH32109.1| 859|Homo sapiens low density
lipoprotein-related protein 12 protein.
Length = 859
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/108 (41%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 35 CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPD 94
C +CD C + DE T CT +CQ+ F C +G+C PRS RC+ CP+
Sbjct: 388 CYTEQQRCDGYWHCPNGRDE--TNCT----MCQKEEFPCSRNGVCYPRSDRCNYQNHCPN 441
Query: 95 GSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
GSDE C C P F C K CV +W+CD DC DGSDE+ C
Sbjct: 442 GSDEKNCFF--CQPGNFHC--KNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/105 (40%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Query: 13 YFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV------CTATKMVC 66
YF SE C +FRC G+CIP +WKC+N +C DSSDE+ A C
Sbjct: 156 YFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPC 215
Query: 67 QEYRFECLSD----GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
+F+CLS C+P S +CD DC D DE C+V CG
Sbjct: 216 AYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCG 260
Score = 72.5 bits (170), Expect = 5e-12
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C + C + C RCD CP+G DE C + C EEF C + G C P +
Sbjct: 375 CLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTM--CQKEEFPC-SRNGVCYPRSD 431
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C+ C +GSDEK C C+ F C N +C+ WV E CP
Sbjct: 432 RCNYQNHCPNGSDEKNC-FFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCP 486
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWV 164
C P E C G G C CD C +G DE C C+ +EF C NG C
Sbjct: 375 CLPWEIPCGGNWG-CYTEQQRCDGYWHCPNGRDETNCT-MCQKEEFPCSRNGVCYPRSDR 432
Query: 165 XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E C CQP +F C + +C+ W CD DC DGSDE C
Sbjct: 433 CNYQNHCPNGSDEKNCFF--CQP-GNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 60.9 bits (141), Expect = 2e-08
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 23 CTSSEFRC-KTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C EF C + G C P S +C+ + C + SDE C CQ F C + C+
Sbjct: 413 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKN--C----FFCQPGNFHC-KNNRCVF 465
Query: 82 RSWRCDATADCPDGSDEHQCEV 103
SW CD+ DC DGSDE C V
Sbjct: 466 ESWVCDSQDDCGDGSDEENCPV 487
Score = 56.0 bits (129), Expect = 5e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA----------CGPEEFTCRG 115
C +F C +G CIP +W+C+ +C D SDE C EA C +F C
Sbjct: 166 CACDQFRC-GNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLS 224
Query: 116 ---KPGECVPLTWMCDDNPDCSDGSDEKACN-ETC 146
K C+P + CD N DC D DE C+ TC
Sbjct: 225 RFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTC 259
Score = 50.4 bits (115), Expect = 2e-05
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-------TEFDCGGG 325
C DQF+C + CIP A CN + +C D SDE C ++ +F C
Sbjct: 166 CACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSR 225
Query: 326 M-----CIPLSKVCDKHVDCPNFEDE 346
C+P S CD ++DC + DE
Sbjct: 226 FTKVYTCLPESLKCDGNIDCLDLGDE 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 11/79 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR 350
C+G CP+G DE NC T+C K EF C G+C P S C+ CPN DE
Sbjct: 395 CDGYWHCPNGRDETNC----TMCQKE-EFPCSRNGVCYPRSDRCNYQNHCPNGSDE--KN 447
Query: 351 CGENECEKNNGGC-SQRCV 368
C C+ N C + RCV
Sbjct: 448 C--FFCQPGNFHCKNNRCV 464
Score = 49.6 bits (113), Expect = 4e-05
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 273 CRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
C+ ++F C + C P + CN CP+GSDE NC C + F C C+ S
Sbjct: 413 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNC----FFC-QPGNFHCKNNRCVFES 467
Query: 332 KVCDKHVDCPNFEDE 346
VCD DC + DE
Sbjct: 468 WVCDSQDDCGDGSDE 482
Score = 48.8 bits (111), Expect = 7e-05
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 25/141 (17%)
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVS-----TPKVRSPCIST 233
K P C F C +G+CI W C+ +C D SDE C T PC
Sbjct: 160 KSEEPNCACDQ-FRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYN 218
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTC--RLDQFQCKDHSCIPGALY 291
+F+C R T V+ E+L+ C GN+ C D+ C +C Y
Sbjct: 219 QFQCLSRFTKVYTC------------LPESLK-CDGNIDCLDLGDEIDCDVPTCGQWLKY 265
Query: 292 CNGVKDCPDGSDEY----NCT 308
G + P+ D Y NCT
Sbjct: 266 FYGTFNSPNYPDFYPPGSNCT 286
Score = 48.8 bits (111), Expect = 7e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
C + CDG C +G DE C C EF C+ C R+
Sbjct: 388 CYTEQQRCDGYWHCPNGRDETNCTM-------CQKEEFPCSRNGVCYPRSDRCNYQNHCP 440
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + C+ F CK++ C+ + C+ DC DGSDE NC
Sbjct: 441 NGSDE-----KNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 46.0 bits (104), Expect = 5e-04
Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 14/95 (14%)
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC------PTPTC-QP--QSH 190
K+ C D+F CGNGKCI W E C PT QP +
Sbjct: 160 KSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQ 219
Query: 191 FSCTDG-----QCISAWWHCDGDVDCADGSDEVGC 220
F C C+ CDG++DC D DE+ C
Sbjct: 220 FQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDC 254
Score = 32.3 bits (70), Expect = 6.6
Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
S+E NC CD +F CG G CIP + C+ +C + DE + C + E
Sbjct: 161 SEEPNCA-----CD---QFRCGNGKCIPEAWKCNNMDECGDSSDE--EICAK-EANPPTA 209
Query: 362 GCSQRCVDTPIGYYCDCEKGYK-LIDNRTCEDIDECADPG 400
Q C K Y L ++ C+ +C D G
Sbjct: 210 AAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLG 249
>AF166350-1|AAD44360.1| 859|Homo sapiens ST7 protein protein.
Length = 859
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/108 (41%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 35 CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPD 94
C +CD C + DE T CT +CQ+ F C +G+C PRS RC+ CP+
Sbjct: 388 CYTEQQRCDGYWHCPNGRDE--TNCT----MCQKEEFPCSRNGVCYPRSDRCNYQNHCPN 441
Query: 95 GSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
GSDE C C P F C K CV +W+CD DC DGSDE+ C
Sbjct: 442 GSDEKNCFF--CQPGNFHC--KNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/105 (40%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Query: 13 YFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV------CTATKMVC 66
YF SE C +FRC G+CIP +WKC+N +C DSSDE+ A C
Sbjct: 156 YFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPC 215
Query: 67 QEYRFECLSD----GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
+F+CLS C+P S +CD DC D DE C+V CG
Sbjct: 216 AYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCG 260
Score = 72.5 bits (170), Expect = 5e-12
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C + C + C RCD CP+G DE C + C EEF C + G C P +
Sbjct: 375 CLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTM--CQKEEFPC-SRNGVCYPRSD 431
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C+ C +GSDEK C C+ F C N +C+ WV E CP
Sbjct: 432 RCNYQNHCPNGSDEKNC-FFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCP 486
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWV 164
C P E C G G C CD C +G DE C C+ +EF C NG C
Sbjct: 375 CLPWEIPCGGNWG-CYTEQQRCDGYWHCPNGRDETNCT-MCQKEEFPCSRNGVCYPRSDR 432
Query: 165 XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E C CQP +F C + +C+ W CD DC DGSDE C
Sbjct: 433 CNYQNHCPNGSDEKNCFF--CQP-GNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 60.9 bits (141), Expect = 2e-08
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 23 CTSSEFRC-KTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C EF C + G C P S +C+ + C + SDE C CQ F C + C+
Sbjct: 413 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKN--C----FFCQPGNFHC-KNNRCVF 465
Query: 82 RSWRCDATADCPDGSDEHQCEV 103
SW CD+ DC DGSDE C V
Sbjct: 466 ESWVCDSQDDCGDGSDEENCPV 487
Score = 56.0 bits (129), Expect = 5e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA----------CGPEEFTCRG 115
C +F C +G CIP +W+C+ +C D SDE C EA C +F C
Sbjct: 166 CACDQFRC-GNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLS 224
Query: 116 ---KPGECVPLTWMCDDNPDCSDGSDEKACN-ETC 146
K C+P + CD N DC D DE C+ TC
Sbjct: 225 RFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTC 259
Score = 50.4 bits (115), Expect = 2e-05
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-------TEFDCGGG 325
C DQF+C + CIP A CN + +C D SDE C ++ +F C
Sbjct: 166 CACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSR 225
Query: 326 M-----CIPLSKVCDKHVDCPNFEDE 346
C+P S CD ++DC + DE
Sbjct: 226 FTKVYTCLPESLKCDGNIDCLDLGDE 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 11/79 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR 350
C+G CP+G DE NC T+C K EF C G+C P S C+ CPN DE
Sbjct: 395 CDGYWHCPNGRDETNC----TMCQKE-EFPCSRNGVCYPRSDRCNYQNHCPNGSDE--KN 447
Query: 351 CGENECEKNNGGC-SQRCV 368
C C+ N C + RCV
Sbjct: 448 C--FFCQPGNFHCKNNRCV 464
Score = 49.6 bits (113), Expect = 4e-05
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 273 CRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
C+ ++F C + C P + CN CP+GSDE NC C + F C C+ S
Sbjct: 413 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNC----FFC-QPGNFHCKNNRCVFES 467
Query: 332 KVCDKHVDCPNFEDE 346
VCD DC + DE
Sbjct: 468 WVCDSQDDCGDGSDE 482
Score = 48.8 bits (111), Expect = 7e-05
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 25/141 (17%)
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVS-----TPKVRSPCIST 233
K P C F C +G+CI W C+ +C D SDE C T PC
Sbjct: 160 KSEEPNCACDQ-FRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYN 218
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTC--RLDQFQCKDHSCIPGALY 291
+F+C R T V+ E+L+ C GN+ C D+ C +C Y
Sbjct: 219 QFQCLSRFTKVYTC------------LPESLK-CDGNIDCLDLGDEIDCDVPTCGQWLKY 265
Query: 292 CNGVKDCPDGSDEY----NCT 308
G + P+ D Y NCT
Sbjct: 266 FYGTFNSPNYPDFYPPGSNCT 286
Score = 48.8 bits (111), Expect = 7e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
C + CDG C +G DE C C EF C+ C R+
Sbjct: 388 CYTEQQRCDGYWHCPNGRDETNCTM-------CQKEEFPCSRNGVCYPRSDRCNYQNHCP 440
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + C+ F CK++ C+ + C+ DC DGSDE NC
Sbjct: 441 NGSDE-----KNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 485
Score = 46.0 bits (104), Expect = 5e-04
Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 14/95 (14%)
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC------PTPTC-QP--QSH 190
K+ C D+F CGNGKCI W E C PT QP +
Sbjct: 160 KSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQ 219
Query: 191 FSCTDG-----QCISAWWHCDGDVDCADGSDEVGC 220
F C C+ CDG++DC D DE+ C
Sbjct: 220 FQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDC 254
Score = 32.3 bits (70), Expect = 6.6
Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
S+E NC CD +F CG G CIP + C+ +C + DE + C + E
Sbjct: 161 SEEPNCA-----CD---QFRCGNGKCIPEAWKCNNMDECGDSSDE--EICAK-EANPPTA 209
Query: 362 GCSQRCVDTPIGYYCDCEKGYK-LIDNRTCEDIDECADPG 400
Q C K Y L ++ C+ +C D G
Sbjct: 210 AAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLG 249
>AB208957-1|BAD92194.1| 793|Homo sapiens suppression of
tumorigenicity variant protein.
Length = 793
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/108 (41%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 35 CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPD 94
C +CD C + DE T CT +CQ+ F C +G+C PRS RC+ CP+
Sbjct: 322 CYTEQQRCDGYWHCPNGRDE--TNCT----MCQKEEFPCSRNGVCYPRSDRCNYQNHCPN 375
Query: 95 GSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
GSDE C C P F C K CV +W+CD DC DGSDE+ C
Sbjct: 376 GSDEKNCFF--CQPGNFHC--KNNRCVFESWVCDSQDDCGDGSDEENC 419
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/105 (40%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Query: 13 YFFLFSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTV------CTATKMVC 66
YF SE C +FRC G+CIP +WKC+N +C DSSDE+ A C
Sbjct: 90 YFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPC 149
Query: 67 QEYRFECLSD----GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
+F+CLS C+P S +CD DC D DE C+V CG
Sbjct: 150 AYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCG 194
Score = 72.5 bits (170), Expect = 5e-12
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTW 125
C + C + C RCD CP+G DE C + C EEF C + G C P +
Sbjct: 309 CLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTM--CQKEEFPC-SRNGVCYPRSD 365
Query: 126 MCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCP 181
C+ C +GSDEK C C+ F C N +C+ WV E CP
Sbjct: 366 RCNYQNHCPNGSDEKNC-FFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCP 420
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCG-NGKCIQMRWV 164
C P E C G G C CD C +G DE C C+ +EF C NG C
Sbjct: 309 CLPWEIPCGGNWG-CYTEQQRCDGYWHCPNGRDETNCT-MCQKEEFPCSRNGVCYPRSDR 366
Query: 165 XXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E C CQP +F C + +C+ W CD DC DGSDE C
Sbjct: 367 CNYQNHCPNGSDEKNCFF--CQP-GNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 419
Score = 60.9 bits (141), Expect = 2e-08
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 23 CTSSEFRC-KTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
C EF C + G C P S +C+ + C + SDE C CQ F C + C+
Sbjct: 347 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKN--C----FFCQPGNFHC-KNNRCVF 399
Query: 82 RSWRCDATADCPDGSDEHQCEV 103
SW CD+ DC DGSDE C V
Sbjct: 400 ESWVCDSQDDCGDGSDEENCPV 421
Score = 56.0 bits (129), Expect = 5e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA----------CGPEEFTCRG 115
C +F C +G CIP +W+C+ +C D SDE C EA C +F C
Sbjct: 100 CACDQFRC-GNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLS 158
Query: 116 ---KPGECVPLTWMCDDNPDCSDGSDEKACN-ETC 146
K C+P + CD N DC D DE C+ TC
Sbjct: 159 RFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTC 193
Score = 50.4 bits (115), Expect = 2e-05
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-------TEFDCGGG 325
C DQF+C + CIP A CN + +C D SDE C ++ +F C
Sbjct: 100 CACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSR 159
Query: 326 M-----CIPLSKVCDKHVDCPNFEDE 346
C+P S CD ++DC + DE
Sbjct: 160 FTKVYTCLPESLKCDGNIDCLDLGDE 185
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 11/79 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCG-GGMCIPLSKVCDKHVDCPNFEDEPRDR 350
C+G CP+G DE NC T+C K EF C G+C P S C+ CPN DE
Sbjct: 329 CDGYWHCPNGRDETNC----TMCQKE-EFPCSRNGVCYPRSDRCNYQNHCPNGSDE--KN 381
Query: 351 CGENECEKNNGGC-SQRCV 368
C C+ N C + RCV
Sbjct: 382 C--FFCQPGNFHCKNNRCV 398
Score = 49.6 bits (113), Expect = 4e-05
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 273 CRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLS 331
C+ ++F C + C P + CN CP+GSDE NC C + F C C+ S
Sbjct: 347 CQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNC----FFC-QPGNFHCKNNRCVFES 401
Query: 332 KVCDKHVDCPNFEDE 346
VCD DC + DE
Sbjct: 402 WVCDSQDDCGDGSDE 416
Score = 48.8 bits (111), Expect = 7e-05
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 25/141 (17%)
Query: 179 KCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVS-----TPKVRSPCIST 233
K P C F C +G+CI W C+ +C D SDE C T PC
Sbjct: 94 KSEEPNCACDQ-FRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYN 152
Query: 234 EFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTC--RLDQFQCKDHSCIPGALY 291
+F+C R T V+ E+L+ C GN+ C D+ C +C Y
Sbjct: 153 QFQCLSRFTKVYTC------------LPESLK-CDGNIDCLDLGDEIDCDVPTCGQWLKY 199
Query: 292 CNGVKDCPDGSDEY----NCT 308
G + P+ D Y NCT
Sbjct: 200 FYGTFNSPNYPDFYPPGSNCT 220
Score = 48.8 bits (111), Expect = 7e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 198 CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXX 257
C + CDG C +G DE C C EF C+ C R+
Sbjct: 322 CYTEQQRCDGYWHCPNGRDETNCTM-------CQKEEFPCSRNGVCYPRSDRCNYQNHCP 374
Query: 258 XXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
E + C+ F CK++ C+ + C+ DC DGSDE NC
Sbjct: 375 NGSDE-----KNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENC 419
Score = 46.0 bits (104), Expect = 5e-04
Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 14/95 (14%)
Query: 140 KACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC------PTPTC-QP--QSH 190
K+ C D+F CGNGKCI W E C PT QP +
Sbjct: 94 KSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQ 153
Query: 191 FSCTDG-----QCISAWWHCDGDVDCADGSDEVGC 220
F C C+ CDG++DC D DE+ C
Sbjct: 154 FQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDC 188
Score = 32.3 bits (70), Expect = 6.6
Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
S+E NC CD +F CG G CIP + C+ +C + DE + C + E
Sbjct: 95 SEEPNCA-----CD---QFRCGNGKCIPEAWKCNNMDECGDSSDE--EICAK-EANPPTA 143
Query: 362 GCSQRCVDTPIGYYCDCEKGYK-LIDNRTCEDIDECADPG 400
Q C K Y L ++ C+ +C D G
Sbjct: 144 AAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLG 183
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 86.2 bits (204), Expect = 4e-16
Identities = 78/256 (30%), Positives = 107/256 (41%), Gaps = 42/256 (16%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD C D G + CV+ C S F +++ TC+HR+
Sbjct: 101 TCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRS 160
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------D 300
E +G V C C PG KDC +
Sbjct: 161 NEGMNCMNKDHGCAHICRETPKGGVAC----------DCRPGFDLAQNQKDCTLTCNYGN 210
Query: 301 GSDEYNCTRQKTI----CDKRTEFDCGGGMCIPLSKV----CDK---------HVDCP-N 342
G +++C T C ++ G CI V CD+ CP
Sbjct: 211 GGCQHSCEDTDTGPMCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVG 270
Query: 343 FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADP 399
F +P + C + NEC NNGGC C +T + C C KGYKL+ D RTC+DIDEC+
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE 330
Query: 400 GSCSQICINEKGTFKC 415
+C ICIN G+F+C
Sbjct: 331 RTCDHICINSPGSFQC 346
Score = 81.4 bits (192), Expect = 1e-14
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Query: 341 PNFEDEPRDRCGENECEKN--NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P ++ E + +ECE + NGGC C++ P Y C C G+ L D C D+DEC
Sbjct: 63 PGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQ 122
Query: 398 D-PGSCSQICINEKGTFKCECHTGY 421
D G C QIC+N G+++C+CH+G+
Sbjct: 123 DNNGGCQQICVNAMGSYECQCHSGF 147
Score = 60.5 bits (140), Expect = 2e-08
Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 339 DC-PNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC 396
DC P F+ + C NGGC C DT G C C + Y L D RTC I+ C
Sbjct: 188 DCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTC--IETC 245
Query: 397 A-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
A + G C + C + +C C G+ P +T CK
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKT-CK 281
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP---GSCSQICIN 408
+EC + C C +TP Y C C+ GYK + + CEDIDEC + G C CIN
Sbjct: 35 DECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVHECIN 93
Query: 409 EKGTFKCECHTGY 421
G ++C C G+
Sbjct: 94 IPGNYRCTCFDGF 106
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC-----EDIDECADPGSCSQIC- 406
+EC+ NNGGC Q CV+ Y C C G+ L DN+ TC E ++ C+ IC
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICR 178
Query: 407 INEKGTFKCECHTGY--ARDPRDRT 429
KG C+C G+ A++ +D T
Sbjct: 179 ETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 35.1 bits (77), Expect = 0.94
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 698 QPDG-----VNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMCVEDSKY 752
QPDG +N C NG C H C R S C C G KLL D++ C + +
Sbjct: 274 QPDGKTCKDINECLVNNGGCDHFC----RNTVGS--FECGCRKGYKLLTDERTCQDIDEC 327
Query: 753 HF 754
F
Sbjct: 328 SF 329
>AL590103-10|CAI12134.1| 179|Homo sapiens heparan sulfate
proteoglycan 2 (perlecan) protein.
Length = 179
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/151 (33%), Positives = 63/151 (41%), Gaps = 13/151 (8%)
Query: 21 RTCTSSEFRCKT-GRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
R CT +EF C + C+ L ++CD DC D SDE C + F L +
Sbjct: 23 RACTEAEFACHSYNECVALEYRCDRRPDCRDMSDE--LNCEEPVLGISP-TFSLLVETTS 79
Query: 80 IPRS-----WRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCS 134
+P R P CGP+E CR G C+P ++CD DC
Sbjct: 80 LPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRN--GHCIPRDYLCDGQEDCE 137
Query: 135 DGSDEKACN--ETCRSDEFTCGNGKCIQMRW 163
DGSDE C C +EF CGNG C W
Sbjct: 138 DGSDELDCGPPPPCEPNEFPCGNGHCALKLW 168
Score = 70.9 bits (166), Expect = 2e-11
Identities = 46/155 (29%), Positives = 57/155 (36%), Gaps = 8/155 (5%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEACG-PEEFTCRGKPGECVPLT 124
C E F C S C+ +RCD DC D SDE CE G F+ + P
Sbjct: 25 CTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPPRP 84
Query: 125 -WMCDDNPDCSDGSDEKACNET----CRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVK 179
P + C E C NG CI ++ E+
Sbjct: 85 ETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELD 144
Query: 180 C-PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCAD 213
C P P C+P + F C +G C W CDGD DC D
Sbjct: 145 CGPPPPCEP-NEFPCGNGHCALKLWRCDGDFDCED 178
Score = 69.7 bits (163), Expect = 4e-11
Identities = 53/154 (34%), Positives = 63/154 (40%), Gaps = 19/154 (12%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCR--SDEFTC--------G 154
AC EF C ECV L + CD PDC D SDE C E S F+
Sbjct: 24 ACTEAEFACHSY-NECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPP 82
Query: 155 NGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG 214
+ MR V+ P P C PQ +C +G CI + CDG DC DG
Sbjct: 83 RPETTIMRQPPVTHAPQPLLPGSVR-PLP-CGPQEA-ACRNGHCIPRDYLCDGQEDCEDG 139
Query: 215 SDEVGCVSTPKVRSPCISTEFECNDRITCVHRAW 248
SDE+ C P PC EF C + C + W
Sbjct: 140 SDELDCGPPP----PCEPNEFPCGNG-HCALKLW 168
Score = 63.7 bits (148), Expect = 2e-09
Identities = 47/162 (29%), Positives = 65/162 (40%), Gaps = 11/162 (6%)
Query: 183 PTCQPQSHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRI 241
P ++ F+C +C++ + CD DC D SDE+ C SP S E
Sbjct: 22 PRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETT--- 78
Query: 242 TCVHRAWVXXXXXXXXXXXXEALELCRGNV---TCRLDQFQCKDHSCIPGALYCNGVKDC 298
+ R + L G+V C + C++ CIP C+G +DC
Sbjct: 79 SLPPRPETTIMRQPPVTHAPQ--PLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDC 136
Query: 299 PDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC 340
DGSDE +C C+ EF CG G C CD DC
Sbjct: 137 EDGSDELDCGPPPP-CEP-NEFPCGNGHCALKLWRCDGDFDC 176
Score = 60.9 bits (141), Expect = 2e-08
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 23 CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPR 82
C E C+ G CIP + CD ++DC D SDE + C+ F C +G C +
Sbjct: 111 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE---LDCGPPPPCEPNEFPC-GNGHCALK 166
Query: 83 SWRCDATADCPD 94
WRCD DC D
Sbjct: 167 LWRCDGDFDCED 178
Score = 35.9 bits (79), Expect = 0.54
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 4/50 (8%)
Query: 319 EFDCGGGMCIPLSKVCDKHVDCPNFEDE----PRDRCGENECEKNNGGCS 364
E C G CIP +CD DC + DE P C NE NG C+
Sbjct: 115 EAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPPPPCEPNEFPCGNGHCA 164
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 85.4 bits (202), Expect = 7e-16
Identities = 114/454 (25%), Positives = 159/454 (35%), Gaps = 76/454 (16%)
Query: 14 FFLFSESRTCTS-SEFR-----CKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV-- 65
F L SE R CT E R C G+C+ + D E C + + + +
Sbjct: 1190 FALDSEERNCTDIDECRISPDLCGRGQCV--NTPGDFECKCDEGYESGFMMMKNCMDIDE 1247
Query: 66 CQEYRFECLSDGLC--IPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVP 122
CQ C G+C S+RC+ + C ++ C C G CV
Sbjct: 1248 CQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN--GRCVN 1304
Query: 123 LT--WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC 180
L + C NP D C + DE + NG C E C
Sbjct: 1305 LIGKYQCACNPGYHSTPDRLFCVDI---DECSIMNGGC-------ETFCTNSEGSYECSC 1354
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP-KVRSPCISTEFECND 239
SCTD C+ + + DG C + P + R C D
Sbjct: 1355 QPGFALMPDQRSCTDID------ECEDNPNICDGGQ---CTNIPGEYRCLCYDGFMASED 1405
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
TCV V E +G+ C D +S G C + +C
Sbjct: 1406 MKTCVD---VNECDLNPNICLSGTCENTKGSFICHCDM----GYSGKKGKTGCTDINECE 1458
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-------GGGM-CIPLSK------VCDKHVDCPNFED 345
G+ +NC + + F C G G+ C L + +C +H DC N
Sbjct: 1459 IGA--HNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG 1516
Query: 346 EPRDRCGE------------NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY-KLIDNRTCE 391
R C E +EC +N C +C++ P GY C+C+ G+ D + CE
Sbjct: 1517 SYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1576
Query: 392 DIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
DIDEC+ P C C N G F+CEC GY D
Sbjct: 1577 DIDECSLPNICVFGTCHNLPGLFRCECEIGYELD 1610
Score = 74.1 bits (174), Expect = 2e-12
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 13/160 (8%)
Query: 270 NVT--CRLDQFQCKDHSCIP--GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
NVT C+L ++ C++ CIP G+ C +C G + + + D+ + C GG
Sbjct: 579 NVTDYCQLVRYLCQNGRCIPTPGSYRC----ECNKGF-QLDLRGECIDVDECEKNPCAGG 633
Query: 326 MCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYK 383
CI R C + +EC +N C+ RC++T ++C C G+
Sbjct: 634 ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFH 693
Query: 384 LI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGY 421
+ D + CED+DEC+ C + +CINE G+FKC C G+
Sbjct: 694 VTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 733
Score = 66.5 bits (155), Expect = 3e-10
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 13/118 (11%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN--FEDEPRDRCGE-NECEKNNGGCSQR---CVDTPIGYY 375
C G+CI + V +CP F ++ C + +EC+ NG QR C++T Y
Sbjct: 1908 CENGVCINM--VGSFRCECPVGFFYNDKLLVCEDIDECQ--NGPVCQRNAECINTAGSYR 1963
Query: 376 CDCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
CDC+ GY+ C D +EC + P CS CI+ G+F C CHTG+ + D+T C
Sbjct: 1964 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND-DQTMC 2020
Score = 64.5 bits (150), Expect = 1e-09
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDP 425
RC+ TP Y C+C KG++L C D+DEC CIN +G++ C+C GY +
Sbjct: 595 RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGY-QST 653
Query: 426 RDRTRCK 432
RT C+
Sbjct: 654 LTRTECR 660
Score = 64.5 bits (150), Expect = 1e-09
Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICD----KRTEFDCGGGM 326
CR+ C C+ PG C C +G E K D +R C GG+
Sbjct: 1205 CRISPDLCGRGQCVNTPGDFECK----CDEGY-ESGFMMMKNCMDIDECQRDPLLCRGGV 1259
Query: 327 CIPLSKVCDKHVDCP-NFEDEPR-DRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
C +CP + P C + NECE + C RCV+ Y C C GY
Sbjct: 1260 CHNTEG--SYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1317
Query: 383 KLIDNRT-CEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
+R C DIDEC+ G C C N +G+++C C G+A P R+
Sbjct: 1318 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1366
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEK 380
C G CI +CP + C + +EC N + C + G+ C CE+
Sbjct: 2268 CKHGQCINTDG--SYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEE 2325
Query: 381 GYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G++ TCEDI+ECA +P C+ C+N G+++C+C GY DR CK
Sbjct: 2326 GFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL-REDRRMCK 2377
Score = 64.5 bits (150), Expect = 1e-09
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
NEC + C+ C +T Y C C KGY L D R+C+D+DECA +C +C+N G
Sbjct: 2577 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIG 2636
Query: 412 TFKCECHTGYAR 423
F C+C G+ +
Sbjct: 2637 GFTCKCPPGFTQ 2648
Score = 63.3 bits (147), Expect = 3e-09
Identities = 104/428 (24%), Positives = 155/428 (36%), Gaps = 48/428 (11%)
Query: 23 CTSSEFRCKTGRCIPL--SWKCDNEKDCS-DSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
C + C+ GRCIP S++C+ K D E V K C EC+++
Sbjct: 584 CQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINN--- 638
Query: 80 IPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL--TWMCDDNPDCSDG 136
S+ C A +C +++ C C G C+ ++ C N
Sbjct: 639 -QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNN--GRCINTDGSFHCVCNAGFHVT 695
Query: 137 SDEKACNETCR-SDEFTCGNGKCIQMRWVXXXXXX-XXXXXXEVKCPTPTCQPQSHFSCT 194
D K C + S C NG CI + + + ++ C
Sbjct: 696 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 755
Query: 195 DGQCISA--WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
+G+C++ + C+ A G D CV T +RS C + R C+ +
Sbjct: 756 NGRCVNTDGSYRCECFPGLAVGLDGRVCVDT-HMRSTC----YGGYKRGQCIKPLFGAVT 810
Query: 253 XXXXXXXXXEAL--ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E E C+ ++Q AL +G GSD C
Sbjct: 811 KSECCCASTEYAFGEPCQPCPAQNSAEYQ---------ALCSSGPGMTSAGSDINECALD 861
Query: 311 KTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFE-DEPRDRCGE-NECEKNNGGCSQ-RC 367
IC G+C L K + +E D C + NEC N+ C +C
Sbjct: 862 PDICPN--------GICENLRGTY-KCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 912
Query: 368 VDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
+TP + C C KG+ D +TCEDIDEC + +C N G+F CEC + DP
Sbjct: 913 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP- 971
Query: 427 DRTRCKAT 434
+T C T
Sbjct: 972 TKTICIET 979
Score = 62.5 bits (145), Expect = 5e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 339 DC-PNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CEDID 394
DC P + +C + NEC++ CS +C+DT +YC C G+K D++T C DI+
Sbjct: 1965 DCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN 2024
Query: 395 ECADPGSCSQICINEKGTFKCECHTGY 421
EC + C N G+F C C+ G+
Sbjct: 2025 ECERDACGNGTCRNTIGSFNCRCNHGF 2051
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/114 (35%), Positives = 55/114 (48%), Gaps = 9/114 (7%)
Query: 322 CGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDC 378
C G CI S C H +D+ C + NECE++ G + C +T + C C
Sbjct: 1991 CSHGQCIDTVGSFYCLCHTGFKTNDDQTM--CLDINECERDACG-NGTCRNTIGSFNCRC 2047
Query: 379 EKGYKLIDNRTCEDIDECADPGS--C-SQICINEKGTFKCECHTGYARDPRDRT 429
G+ L N C D+DECA C + CIN G+F+C+C+ GY P RT
Sbjct: 2048 NHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRT 2101
Score = 60.5 bits (140), Expect = 2e-08
Identities = 83/358 (23%), Positives = 131/358 (36%), Gaps = 32/358 (8%)
Query: 92 CPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNE-TCRSDE 150
C + ++CE C P +T G ECV NP C +G+ + C +E
Sbjct: 2273 CINTDGSYRCE---C-PFGYTLAGN--ECVDTDECSVGNP-CGNGTCKNVIGGFECTCEE 2325
Query: 151 -------FTCGN-GKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD-GQCISA 201
TC + +C Q + E KCP + C D +C
Sbjct: 2326 GFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEG 2385
Query: 202 WWHC-DGDVDCADGSDEVGCVSTPKV-RSPCISTEFECNDRITCVHRAWVXXXXXXXXXX 259
C + ++C + C+ P R P C D C + +
Sbjct: 2386 KHDCTEKQMECKNLIGTYMCICGPGYQRRP---DGEGCVDENECQTKPGICENGRCLNTR 2442
Query: 260 XXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKD-CPDGSDEYN-CTRQKTICDKR 317
E C T +Q +C D+ G + +++ C GS N T+ + CD
Sbjct: 2443 GSYTCE-CNDGFTASPNQDECLDNR--EGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGG 2499
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC 376
+ +C V K + CP+ + +EC+ + C CV+ Y+C
Sbjct: 2500 RGWGPHCEICPFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC 2558
Query: 377 DCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C+ GY I +C D++EC P C+ IC N +G+++C C GY D CK
Sbjct: 2559 ICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ-EDGRSCK 2615
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA 397
P F NEC + C + C +TP + C+C++G+ L +CED+DEC
Sbjct: 2644 PGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE 2703
Query: 398 DPGSCSQICINEKGTFKCECHTGY 421
C C N G ++C C GY
Sbjct: 2704 GNHRCQHGCQNIIGGYRCSCPQGY 2727
Score = 59.3 bits (137), Expect = 5e-08
Identities = 47/174 (27%), Positives = 66/174 (37%), Gaps = 16/174 (9%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTEFD-----CG 323
D +C D C G C+ DC + Y C T C E CG
Sbjct: 1488 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG 1547
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
G C+ D C + +EC N C + P + C+CE GY
Sbjct: 1548 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGY 1607
Query: 383 KLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
+L C D++EC DP +C S C+N G++ C+C + +P R C T
Sbjct: 1608 ELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNP-TRVGCVDT 1660
Score = 58.4 bits (135), Expect = 9e-08
Identities = 57/172 (33%), Positives = 73/172 (42%), Gaps = 26/172 (15%)
Query: 269 GNVTCR--LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM 326
GN TCR + F C+ C G + + DC D DE C C G
Sbjct: 2032 GNGTCRNTIGSFNCR---CNHGFILSHN-NDCID-VDE---------CASGNGNLCRNGQ 2077
Query: 327 CIPLSKVCDKHVDC-PNFEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
CI + V C +E P R C + NEC C+ C + Y C C GY
Sbjct: 2078 CI--NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 2135
Query: 383 KLIDNRTCEDIDECA-DPGSCS-QICINEKGTFKCECHTGYARDPRDRTRCK 432
L N CEDIDEC +P C+ C N +G+FKC C G++ R RC+
Sbjct: 2136 SL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGR-RCQ 2185
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSC-SQICINE 409
+EC+ G C C++T + C C G+KL + ++ CEDIDEC+ PG C C N
Sbjct: 379 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 438
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
++ C+C G+ P D TRC
Sbjct: 439 VSSYFCKCPPGFYTSP-DGTRC 459
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C KGY I CEDIDEC PG C +C+N +G+FKC+C +G D R
Sbjct: 1027 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 1079
Score = 56.8 bits (131), Expect = 3e-07
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 346 EPRDRC-GENECEKNNGGCSQRCVDTP--IG-YYCDCEKGY-KLIDNRTCEDIDEC-ADP 399
E R C E+ECE+ C+++ ++ IG Y C C GY + D C D +EC P
Sbjct: 2371 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2430
Query: 400 GSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
G C C+N +G++ CEC+ G+ P EG+
Sbjct: 2431 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY 2469
Score = 55.6 bits (128), Expect = 6e-07
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQ-ICINEK 410
+EC++ G C +C++T + C C GY L D R C+D++EC PG C C N
Sbjct: 1739 DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTV 1798
Query: 411 GTFKCECHTGY 421
G + C C Y
Sbjct: 1799 GNYTCICPPDY 1809
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGT 412
+EC++ + +C++T Y C+C GY L N C D DEC+ C C N G
Sbjct: 2260 DECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNE-CVDTDECSVGNPCGNGTCKNVIGG 2318
Query: 413 FKCECHTGYARDP 425
F+C C G+ P
Sbjct: 2319 FECTCEEGFEPGP 2331
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGY-----KLIDNRTC-EDIDECADPGSCSQICI 407
+EC C CV+T G+ C C G+ IDN C DI+ C G IC
Sbjct: 2618 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG----ICQ 2673
Query: 408 NEKGTFKCECHTGYARD 424
N G+F CEC G++ D
Sbjct: 2674 NTPGSFTCECQRGFSLD 2690
Score = 46.0 bits (104), Expect = 5e-04
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 353 ENECEKNN--GGCSQRCVDTPIGYYCDCEKGYKLID-NRTCEDIDECADPGS-CSQICIN 408
ENEC + GG S C +T Y C C G++ + C+DI+EC + CS C N
Sbjct: 2739 ENECLSAHICGGAS--CHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSN 2796
Query: 409 EKGTFKCECHTGYAR 423
+G + C C GY R
Sbjct: 2797 TEGGYLCGCPPGYFR 2811
Score = 41.9 bits (94), Expect = 0.008
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C CIN G+F+C+C G+
Sbjct: 362 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGH 408
Score = 39.5 bits (88), Expect = 0.044
Identities = 15/31 (48%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 392 DIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
D+DEC +P C CIN G+++CEC GY
Sbjct: 2258 DMDECKEPDVCKHGQCINTDGSYRCECPFGY 2288
Score = 36.7 bits (81), Expect = 0.31
Identities = 38/133 (28%), Positives = 51/133 (38%), Gaps = 16/133 (12%)
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS-DEYNCTRQKTICDKRTEF 320
E ++ C GN C Q C++ I G C+ CP G Y + + +
Sbjct: 2697 EDVDECEGNHRC---QHGCQN---IIGGYRCS----CPQGYLQHYQWNQCVDENECLSAH 2746
Query: 321 DCGGGMCIPLSKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCD 377
CGG C + + CP F+ E C + NEC CS C +T GY C
Sbjct: 2747 ICGGASCH--NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCG 2804
Query: 378 CEKGYKLIDNRTC 390
C GY I C
Sbjct: 2805 CPPGYFRIGQGHC 2817
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC P C+ C N G+FKC C +G+A D +R
Sbjct: 1158 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1197
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 85.4 bits (202), Expect = 7e-16
Identities = 114/454 (25%), Positives = 159/454 (35%), Gaps = 76/454 (16%)
Query: 14 FFLFSESRTCTS-SEFR-----CKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV-- 65
F L SE R CT E R C G+C+ + D E C + + + +
Sbjct: 1059 FALDSEERNCTDIDECRISPDLCGRGQCV--NTPGDFECKCDEGYESGFMMMKNCMDIDE 1116
Query: 66 CQEYRFECLSDGLC--IPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVP 122
CQ C G+C S+RC+ + C ++ C C G CV
Sbjct: 1117 CQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN--GRCVN 1173
Query: 123 LT--WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC 180
L + C NP D C + DE + NG C E C
Sbjct: 1174 LIGKYQCACNPGYHSTPDRLFCVDI---DECSIMNGGC-------ETFCTNSEGSYECSC 1223
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP-KVRSPCISTEFECND 239
SCTD C+ + + DG C + P + R C D
Sbjct: 1224 QPGFALMPDQRSCTDID------ECEDNPNICDGGQ---CTNIPGEYRCLCYDGFMASED 1274
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
TCV V E +G+ C D +S G C + +C
Sbjct: 1275 MKTCVD---VNECDLNPNICLSGTCENTKGSFICHCDM----GYSGKKGKTGCTDINECE 1327
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-------GGGM-CIPLSK------VCDKHVDCPNFED 345
G+ +NC + + F C G G+ C L + +C +H DC N
Sbjct: 1328 IGA--HNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG 1385
Query: 346 EPRDRCGE------------NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY-KLIDNRTCE 391
R C E +EC +N C +C++ P GY C+C+ G+ D + CE
Sbjct: 1386 SYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1445
Query: 392 DIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
DIDEC+ P C C N G F+CEC GY D
Sbjct: 1446 DIDECSLPNICVFGTCHNLPGLFRCECEIGYELD 1479
Score = 74.1 bits (174), Expect = 2e-12
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 13/160 (8%)
Query: 270 NVT--CRLDQFQCKDHSCIP--GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
NVT C+L ++ C++ CIP G+ C +C G + + + D+ + C GG
Sbjct: 448 NVTDYCQLVRYLCQNGRCIPTPGSYRC----ECNKGF-QLDLRGECIDVDECEKNPCAGG 502
Query: 326 MCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYK 383
CI R C + +EC +N C+ RC++T ++C C G+
Sbjct: 503 ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFH 562
Query: 384 LI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGY 421
+ D + CED+DEC+ C + +CINE G+FKC C G+
Sbjct: 563 VTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
Score = 66.5 bits (155), Expect = 3e-10
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 13/118 (11%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN--FEDEPRDRCGE-NECEKNNGGCSQR---CVDTPIGYY 375
C G+CI + V +CP F ++ C + +EC+ NG QR C++T Y
Sbjct: 1777 CENGVCINM--VGSFRCECPVGFFYNDKLLVCEDIDECQ--NGPVCQRNAECINTAGSYR 1832
Query: 376 CDCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
CDC+ GY+ C D +EC + P CS CI+ G+F C CHTG+ + D+T C
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND-DQTMC 1889
Score = 64.5 bits (150), Expect = 1e-09
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDP 425
RC+ TP Y C+C KG++L C D+DEC CIN +G++ C+C GY +
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGY-QST 522
Query: 426 RDRTRCK 432
RT C+
Sbjct: 523 LTRTECR 529
Score = 64.5 bits (150), Expect = 1e-09
Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICD----KRTEFDCGGGM 326
CR+ C C+ PG C C +G E K D +R C GG+
Sbjct: 1074 CRISPDLCGRGQCVNTPGDFECK----CDEGY-ESGFMMMKNCMDIDECQRDPLLCRGGV 1128
Query: 327 CIPLSKVCDKHVDCP-NFEDEPR-DRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
C +CP + P C + NECE + C RCV+ Y C C GY
Sbjct: 1129 CHNTEG--SYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 383 KLIDNRT-CEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
+R C DIDEC+ G C C N +G+++C C G+A P R+
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEK 380
C G CI +CP + C + +EC N + C + G+ C CE+
Sbjct: 2137 CKHGQCINTDG--SYRCECPFGYTLAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEE 2194
Query: 381 GYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G++ TCEDI+ECA +P C+ C+N G+++C+C GY DR CK
Sbjct: 2195 GFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL-REDRRMCK 2246
Score = 64.5 bits (150), Expect = 1e-09
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
NEC + C+ C +T Y C C KGY L D R+C+D+DECA +C +C+N G
Sbjct: 2446 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIG 2505
Query: 412 TFKCECHTGYAR 423
F C+C G+ +
Sbjct: 2506 GFTCKCPPGFTQ 2517
Score = 63.3 bits (147), Expect = 3e-09
Identities = 104/428 (24%), Positives = 155/428 (36%), Gaps = 48/428 (11%)
Query: 23 CTSSEFRCKTGRCIPL--SWKCDNEKDCS-DSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
C + C+ GRCIP S++C+ K D E V K C EC+++
Sbjct: 453 CQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINN--- 507
Query: 80 IPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL--TWMCDDNPDCSDG 136
S+ C A +C +++ C C G C+ ++ C N
Sbjct: 508 -QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNN--GRCINTDGSFHCVCNAGFHVT 564
Query: 137 SDEKACNETCR-SDEFTCGNGKCIQMRWVXXXXXX-XXXXXXEVKCPTPTCQPQSHFSCT 194
D K C + S C NG CI + + + ++ C
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 195 DGQCISA--WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXX 252
+G+C++ + C+ A G D CV T +RS C + R C+ +
Sbjct: 625 NGRCVNTDGSYRCECFPGLAVGLDGRVCVDT-HMRSTC----YGGYKRGQCIKPLFGAVT 679
Query: 253 XXXXXXXXXEAL--ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQ 310
E E C+ ++Q AL +G GSD C
Sbjct: 680 KSECCCASTEYAFGEPCQPCPAQNSAEYQ---------ALCSSGPGMTSAGSDINECALD 730
Query: 311 KTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFE-DEPRDRCGE-NECEKNNGGCSQ-RC 367
IC G+C L K + +E D C + NEC N+ C +C
Sbjct: 731 PDICPN--------GICENLRGTY-KCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
Query: 368 VDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDPR 426
+TP + C C KG+ D +TCEDIDEC + +C N G+F CEC + DP
Sbjct: 782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP- 840
Query: 427 DRTRCKAT 434
+T C T
Sbjct: 841 TKTICIET 848
Score = 62.5 bits (145), Expect = 5e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 339 DC-PNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CEDID 394
DC P + +C + NEC++ CS +C+DT +YC C G+K D++T C DI+
Sbjct: 1834 DCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN 1893
Query: 395 ECADPGSCSQICINEKGTFKCECHTGY 421
EC + C N G+F C C+ G+
Sbjct: 1894 ECERDACGNGTCRNTIGSFNCRCNHGF 1920
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/114 (35%), Positives = 55/114 (48%), Gaps = 9/114 (7%)
Query: 322 CGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDC 378
C G CI S C H +D+ C + NECE++ G + C +T + C C
Sbjct: 1860 CSHGQCIDTVGSFYCLCHTGFKTNDDQTM--CLDINECERDACG-NGTCRNTIGSFNCRC 1916
Query: 379 EKGYKLIDNRTCEDIDECADPGS--C-SQICINEKGTFKCECHTGYARDPRDRT 429
G+ L N C D+DECA C + CIN G+F+C+C+ GY P RT
Sbjct: 1917 NHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRT 1970
Score = 60.5 bits (140), Expect = 2e-08
Identities = 83/358 (23%), Positives = 131/358 (36%), Gaps = 32/358 (8%)
Query: 92 CPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNE-TCRSDE 150
C + ++CE C P +T G ECV NP C +G+ + C +E
Sbjct: 2142 CINTDGSYRCE---C-PFGYTLAGN--ECVDTDECSVGNP-CGNGTCKNVIGGFECTCEE 2194
Query: 151 -------FTCGN-GKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTD-GQCISA 201
TC + +C Q + E KCP + C D +C
Sbjct: 2195 GFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEG 2254
Query: 202 WWHC-DGDVDCADGSDEVGCVSTPKV-RSPCISTEFECNDRITCVHRAWVXXXXXXXXXX 259
C + ++C + C+ P R P C D C + +
Sbjct: 2255 KHDCTEKQMECKNLIGTYMCICGPGYQRRP---DGEGCVDENECQTKPGICENGRCLNTR 2311
Query: 260 XXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKD-CPDGSDEYN-CTRQKTICDKR 317
E C T +Q +C D+ G + +++ C GS N T+ + CD
Sbjct: 2312 GSYTCE-CNDGFTASPNQDECLDNR--EGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGG 2368
Query: 318 TEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYC 376
+ +C V K + CP+ + +EC+ + C CV+ Y+C
Sbjct: 2369 RGWGPHCEICPFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC 2427
Query: 377 DCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C+ GY I +C D++EC P C+ IC N +G+++C C GY D CK
Sbjct: 2428 ICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ-EDGRSCK 2484
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA 397
P F NEC + C + C +TP + C+C++G+ L +CED+DEC
Sbjct: 2513 PGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE 2572
Query: 398 DPGSCSQICINEKGTFKCECHTGY 421
C C N G ++C C GY
Sbjct: 2573 GNHRCQHGCQNIIGGYRCSCPQGY 2596
Score = 59.3 bits (137), Expect = 5e-08
Identities = 47/174 (27%), Positives = 66/174 (37%), Gaps = 16/174 (9%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTEFD-----CG 323
D +C D C G C+ DC + Y C T C E CG
Sbjct: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG 1416
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
G C+ D C + +EC N C + P + C+CE GY
Sbjct: 1417 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGY 1476
Query: 383 KLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
+L C D++EC DP +C S C+N G++ C+C + +P R C T
Sbjct: 1477 ELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNP-TRVGCVDT 1529
Score = 58.4 bits (135), Expect = 9e-08
Identities = 57/172 (33%), Positives = 73/172 (42%), Gaps = 26/172 (15%)
Query: 269 GNVTCR--LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM 326
GN TCR + F C+ C G + + DC D DE C C G
Sbjct: 1901 GNGTCRNTIGSFNCR---CNHGFILSHN-NDCID-VDE---------CASGNGNLCRNGQ 1946
Query: 327 CIPLSKVCDKHVDC-PNFEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
CI + V C +E P R C + NEC C+ C + Y C C GY
Sbjct: 1947 CI--NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004
Query: 383 KLIDNRTCEDIDECA-DPGSCS-QICINEKGTFKCECHTGYARDPRDRTRCK 432
L N CEDIDEC +P C+ C N +G+FKC C G++ R RC+
Sbjct: 2005 SL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGR-RCQ 2054
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSC-SQICINE 409
+EC+ G C C++T + C C G+KL + ++ CEDIDEC+ PG C C N
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
++ C+C G+ P D TRC
Sbjct: 308 VSSYFCKCPPGFYTSP-DGTRC 328
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C KGY I CEDIDEC PG C +C+N +G+FKC+C +G D R
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Score = 56.8 bits (131), Expect = 3e-07
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 346 EPRDRC-GENECEKNNGGCSQRCVDTP--IG-YYCDCEKGY-KLIDNRTCEDIDEC-ADP 399
E R C E+ECE+ C+++ ++ IG Y C C GY + D C D +EC P
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 400 GSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
G C C+N +G++ CEC+ G+ P EG+
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY 2338
Score = 55.6 bits (128), Expect = 6e-07
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQ-ICINEK 410
+EC++ G C +C++T + C C GY L D R C+D++EC PG C C N
Sbjct: 1608 DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTV 1667
Query: 411 GTFKCECHTGY 421
G + C C Y
Sbjct: 1668 GNYTCICPPDY 1678
Score = 51.6 bits (118), Expect = 1e-05
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGT 412
+EC++ + +C++T Y C+C GY L N C D DEC+ C C N G
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYTLAGNE-CVDTDECSVGNPCGNGTCKNVIGG 2187
Query: 413 FKCECHTGYARDP 425
F+C C G+ P
Sbjct: 2188 FECTCEEGFEPGP 2200
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGY-----KLIDNRTC-EDIDECADPGSCSQICI 407
+EC C CV+T G+ C C G+ IDN C DI+ C G IC
Sbjct: 2487 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG----ICQ 2542
Query: 408 NEKGTFKCECHTGYARD 424
N G+F CEC G++ D
Sbjct: 2543 NTPGSFTCECQRGFSLD 2559
Score = 46.0 bits (104), Expect = 5e-04
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 353 ENECEKNN--GGCSQRCVDTPIGYYCDCEKGYKLID-NRTCEDIDECADPGS-CSQICIN 408
ENEC + GG S C +T Y C C G++ + C+DI+EC + CS C N
Sbjct: 2608 ENECLSAHICGGAS--CHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSN 2665
Query: 409 EKGTFKCECHTGYAR 423
+G + C C GY R
Sbjct: 2666 TEGGYLCGCPPGYFR 2680
Score = 41.9 bits (94), Expect = 0.008
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C CIN G+F+C+C G+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGH 277
Score = 39.5 bits (88), Expect = 0.044
Identities = 15/31 (48%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 392 DIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
D+DEC +P C CIN G+++CEC GY
Sbjct: 2127 DMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
Score = 36.7 bits (81), Expect = 0.31
Identities = 38/133 (28%), Positives = 51/133 (38%), Gaps = 16/133 (12%)
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS-DEYNCTRQKTICDKRTEF 320
E ++ C GN C Q C++ I G C+ CP G Y + + +
Sbjct: 2566 EDVDECEGNHRC---QHGCQN---IIGGYRCS----CPQGYLQHYQWNQCVDENECLSAH 2615
Query: 321 DCGGGMCIPLSKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCD 377
CGG C + + CP F+ E C + NEC CS C +T GY C
Sbjct: 2616 ICGGASCH--NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCG 2673
Query: 378 CEKGYKLIDNRTC 390
C GY I C
Sbjct: 2674 CPPGYFRIGQGHC 2686
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC P C+ C N G+FKC C +G+A D +R
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1066
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 85.4 bits (202), Expect = 7e-16
Identities = 114/454 (25%), Positives = 159/454 (35%), Gaps = 76/454 (16%)
Query: 14 FFLFSESRTCTS-SEFR-----CKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMV-- 65
F L SE R CT E R C G+C+ + D E C + + + +
Sbjct: 1059 FALDSEERNCTDIDECRISPDLCGRGQCV--NTPGDFECKCDEGYESGFMMMKNCMDIDE 1116
Query: 66 CQEYRFECLSDGLC--IPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVP 122
CQ C G+C S+RC+ + C ++ C C G CV
Sbjct: 1117 CQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN--GRCVN 1173
Query: 123 LT--WMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKC 180
L + C NP D C + DE + NG C E C
Sbjct: 1174 LIGKYQCACNPGYHSTPDRLFCVDI---DECSIMNGGC-------ETFCTNSEGSYECSC 1223
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP-KVRSPCISTEFECND 239
SCTD C+ + + DG C + P + R C D
Sbjct: 1224 QPGFALMPDQRSCTDID------ECEDNPNICDGGQ---CTNIPGEYRCLCYDGFMASED 1274
Query: 240 RITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP 299
TCV V E +G+ C D +S G C + +C
Sbjct: 1275 MKTCVD---VNECDLNPNICLSGTCENTKGSFICHCDM----GYSGKKGKTGCTDINECE 1327
Query: 300 DGSDEYNCTRQKTICDKRTEFDC-------GGGM-CIPLSK------VCDKHVDCPNFED 345
G+ +NC + + F C G G+ C L + +C +H DC N
Sbjct: 1328 IGA--HNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG 1385
Query: 346 EPRDRCGE------------NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY-KLIDNRTCE 391
R C E +EC +N C +C++ P GY C+C+ G+ D + CE
Sbjct: 1386 SYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1445
Query: 392 DIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
DIDEC+ P C C N G F+CEC GY D
Sbjct: 1446 DIDECSLPNICVFGTCHNLPGLFRCECEIGYELD 1479
Score = 74.5 bits (175), Expect = 1e-12
Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Query: 270 NVT--CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC 327
NVT C+L ++ C++ CIP C +C G + + + D+ + C GG C
Sbjct: 448 NVTDYCQLVRYLCQNGRCIPTPGSCRC--ECNKGF-QLDLRGECIDVDECEKNPCAGGEC 504
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI 385
I R C + +EC +N C+ RC++T ++C C G+ +
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGY 421
D + CED+DEC+ C + +CINE G+FKC C G+
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
Score = 66.5 bits (155), Expect = 3e-10
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 13/118 (11%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN--FEDEPRDRCGE-NECEKNNGGCSQR---CVDTPIGYY 375
C G+CI + V +CP F ++ C + +EC+ NG QR C++T Y
Sbjct: 1777 CENGVCINM--VGSFRCECPVGFFYNDKLLVCEDIDECQ--NGPVCQRNAECINTAGSYR 1832
Query: 376 CDCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
CDC+ GY+ C D +EC + P CS CI+ G+F C CHTG+ + D+T C
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND-DQTMC 1889
Score = 64.5 bits (150), Expect = 1e-09
Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICD----KRTEFDCGGGM 326
CR+ C C+ PG C C +G E K D +R C GG+
Sbjct: 1074 CRISPDLCGRGQCVNTPGDFECK----CDEGY-ESGFMMMKNCMDIDECQRDPLLCRGGV 1128
Query: 327 CIPLSKVCDKHVDCP-NFEDEPR-DRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
C +CP + P C + NECE + C RCV+ Y C C GY
Sbjct: 1129 CHNTEG--SYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 383 KLIDNRT-CEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
+R C DIDEC+ G C C N +G+++C C G+A P R+
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
Score = 64.5 bits (150), Expect = 1e-09
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKG 411
NEC + C+ C +T Y C C KGY L D R+C+D+DECA +C +C+N G
Sbjct: 2446 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIG 2505
Query: 412 TFKCECHTGYAR 423
F C+C G+ +
Sbjct: 2506 GFTCKCPPGFTQ 2517
Score = 63.7 bits (148), Expect = 2e-09
Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEK 380
C G CI +CP + C + +EC N + C + G+ C CE+
Sbjct: 2137 CKHGQCINTDG--SYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEE 2194
Query: 381 GYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
G++ TCEDI+ECA +P C+ C+N G+++C+C GY DR CK
Sbjct: 2195 GFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL-REDRRMCK 2246
Score = 62.9 bits (146), Expect = 4e-09
Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKG 411
NEC N+ C +C +TP + C C KG+ D +TCEDIDEC + +C N G
Sbjct: 767 NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPG 826
Query: 412 TFKCECHTGYARDPRDRTRCKAT 434
+F CEC + DP +T C T
Sbjct: 827 SFICECSSESTLDP-TKTICIET 848
Score = 62.5 bits (145), Expect = 5e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 339 DC-PNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CEDID 394
DC P + +C + NEC++ CS +C+DT +YC C G+K D++T C DI+
Sbjct: 1834 DCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN 1893
Query: 395 ECADPGSCSQICINEKGTFKCECHTGY 421
EC + C N G+F C C+ G+
Sbjct: 1894 ECERDACGNGTCRNTIGSFNCRCNHGF 1920
Score = 61.7 bits (143), Expect = 9e-09
Identities = 47/159 (29%), Positives = 69/159 (43%), Gaps = 14/159 (8%)
Query: 275 LDQFQCKDHSCIPGALYCN-GVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGGMCI 328
+D +C+ + C G N G C + Y T +T C E C G CI
Sbjct: 489 IDVDECEKNPCAGGECINNQGSYTCQCRAG-YQSTLTRTECRDIDECLQNGRICNNGRCI 547
Query: 329 PLSKVCDKHVDCPNFEDEPRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
H C RD C + +EC N + C++ + C C+ G++L
Sbjct: 548 NTDG--SFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLA 605
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
D R C+DI+EC PG C + C+N G+++CEC G A
Sbjct: 606 SDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLA 644
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/114 (35%), Positives = 55/114 (48%), Gaps = 9/114 (7%)
Query: 322 CGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDC 378
C G CI S C H +D+ C + NECE++ G + C +T + C C
Sbjct: 1860 CSHGQCIDTVGSFYCLCHTGFKTNDDQTM--CLDINECERDACG-NGTCRNTIGSFNCRC 1916
Query: 379 EKGYKLIDNRTCEDIDECADPGS--C-SQICINEKGTFKCECHTGYARDPRDRT 429
G+ L N C D+DECA C + CIN G+F+C+C+ GY P RT
Sbjct: 1917 NHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRT 1970
Score = 60.9 bits (141), Expect = 2e-08
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDP 425
RC+ TP C+C KG++L C D+DEC CIN +G++ C+C GY +
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGY-QST 522
Query: 426 RDRTRCK 432
RT C+
Sbjct: 523 LTRTECR 529
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA 397
P F NEC + C + C +TP + C+C++G+ L +CED+DEC
Sbjct: 2513 PGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE 2572
Query: 398 DPGSCSQICINEKGTFKCECHTGY 421
C C N G ++C C GY
Sbjct: 2573 GNHRCQHGCQNIIGGYRCSCPQGY 2596
Score = 59.3 bits (137), Expect = 5e-08
Identities = 47/174 (27%), Positives = 66/174 (37%), Gaps = 16/174 (9%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTEFD-----CG 323
D +C D C G C+ DC + Y C T C E CG
Sbjct: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG 1416
Query: 324 GGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
G C+ D C + +EC N C + P + C+CE GY
Sbjct: 1417 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGY 1476
Query: 383 KLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDPRDRTRCKAT 434
+L C D++EC DP +C S C+N G++ C+C + +P R C T
Sbjct: 1477 ELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNP-TRVGCVDT 1529
Score = 59.3 bits (137), Expect = 5e-08
Identities = 71/307 (23%), Positives = 111/307 (36%), Gaps = 18/307 (5%)
Query: 136 GSDEKACNETCRSDEF-TCGN-GKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSC 193
G E C E TC + +C Q + E KCP + C
Sbjct: 2186 GGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC 2245
Query: 194 TD-GQCISAWWHC-DGDVDCADGSDEVGCVSTPKV-RSPCISTEFECNDRITCVHRAWVX 250
D +C C + ++C + C+ P R P C D C + +
Sbjct: 2246 KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRP---DGEGCVDENECQTKPGIC 2302
Query: 251 XXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKD-CPDGSDEYN-CT 308
E C T +Q +C D+ G + +++ C GS N T
Sbjct: 2303 ENGRCLNTRGSYTCE-CNDGFTASPNQDECLDNR--EGYCFTEVLQNMCQIGSSNRNPVT 2359
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RC 367
+ + CD + +C V K + CP+ + +EC+ + C C
Sbjct: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKL-CPHGRGFMTNGADIDECKVIHDVCRNGEC 2418
Query: 368 VDTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDP 425
V+ Y+C C+ GY I +C D++EC P C+ IC N +G+++C C GY
Sbjct: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ- 2477
Query: 426 RDRTRCK 432
D CK
Sbjct: 2478 EDGRSCK 2484
Score = 58.4 bits (135), Expect = 9e-08
Identities = 57/172 (33%), Positives = 73/172 (42%), Gaps = 26/172 (15%)
Query: 269 GNVTCR--LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGM 326
GN TCR + F C+ C G + + DC D DE C C G
Sbjct: 1901 GNGTCRNTIGSFNCR---CNHGFILSHN-NDCID-VDE---------CASGNGNLCRNGQ 1946
Query: 327 CIPLSKVCDKHVDC-PNFEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
CI + V C +E P R C + NEC C+ C + Y C C GY
Sbjct: 1947 CI--NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004
Query: 383 KLIDNRTCEDIDECA-DPGSCS-QICINEKGTFKCECHTGYARDPRDRTRCK 432
L N CEDIDEC +P C+ C N +G+FKC C G++ R RC+
Sbjct: 2005 SL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGR-RCQ 2054
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSC-SQICINE 409
+EC+ G C C++T + C C G+KL + ++ CEDIDEC+ PG C C N
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
++ C+C G+ P D TRC
Sbjct: 308 VSSYFCKCPPGFYTSP-DGTRC 328
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C KGY I CEDIDEC PG C +C+N +G+FKC+C +G D R
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Score = 56.8 bits (131), Expect = 3e-07
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 346 EPRDRC-GENECEKNNGGCSQRCVDTP--IG-YYCDCEKGY-KLIDNRTCEDIDEC-ADP 399
E R C E+ECE+ C+++ ++ IG Y C C GY + D C D +EC P
Sbjct: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 400 GSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
G C C+N +G++ CEC+ G+ P EG+
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGY 2338
Score = 55.6 bits (128), Expect = 6e-07
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQ-ICINEK 410
+EC++ G C +C++T + C C GY L D R C+D++EC PG C C N
Sbjct: 1608 DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTV 1667
Query: 411 GTFKCECHTGY 421
G + C C Y
Sbjct: 1668 GNYTCICPPDY 1678
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGY-----KLIDNRTC-EDIDECADPGSCSQICI 407
+EC C CV+T G+ C C G+ IDN C DI+ C G IC
Sbjct: 2487 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG----ICQ 2542
Query: 408 NEKGTFKCECHTGYARD 424
N G+F CEC G++ D
Sbjct: 2543 NTPGSFTCECQRGFSLD 2559
Score = 50.8 bits (116), Expect = 2e-05
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGT 412
+EC++ + +C++T Y C+C GY L N C D DEC+ C C N G
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILAGNE-CVDTDECSVGNPCGNGTCKNVIGG 2187
Query: 413 FKCECHTGYARDP 425
F+C C G+ P
Sbjct: 2188 FECTCEEGFEPGP 2200
Score = 46.8 bits (106), Expect = 3e-04
Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 16/161 (9%)
Query: 272 TCR-LDQFQCKDHSCIPGALYCNG--VKDCPDGSDEYNCTR-QKTICDKRTEFDCGG-GM 326
+C+ LD+ K H+C + G CP G +++ + C CG G+
Sbjct: 2482 SCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINL-CGSKGI 2540
Query: 327 C--IPLSKVCDKHVDCPNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
C P S C+ F D+ C + +ECE N+ C C + GY C C +GY
Sbjct: 2541 CQNTPGSFTCECQ---RGFSLDQTGSSCEDVDECEGNHR-CQHGCQNIIGGYRCSCPQGY 2596
Query: 383 -KLIDNRTCEDIDECADPGSCSQI-CINEKGTFKCECHTGY 421
+ C D +EC C C N G++KC C G+
Sbjct: 2597 LQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGF 2637
Score = 43.6 bits (98), Expect = 0.003
Identities = 78/335 (23%), Positives = 116/335 (34%), Gaps = 46/335 (13%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD---EKACNETCRSDEFTCGNGKCI--Q 160
C + C+ G C+P C +C+ G C + ++ C G+CI Q
Sbjct: 453 CQLVRYLCQN--GRCIPTPGSC--RCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQ 508
Query: 161 MRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
+ +C Q+ C +G+CI+ DG C + G
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT----DGSFHCVCNA---GF 561
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQC 280
T ++ C + EC+ R C++ + +C+ D C
Sbjct: 562 HVTRDGKN-CEDMD-ECSIRNMCLNGMCINEDGSFKC--------ICKPGFQLASDGRYC 611
Query: 281 KD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP--LSKVCD-- 335
KD + C + NG DGS Y C C G +C+ + C
Sbjct: 612 KDINECETPGICMNGRCVNTDGS--YRCE-----CFPGLAVGLDGRVCVDTHMRSTCYGG 664
Query: 336 -KHVDC--PNFEDEPRDRCGENECEKNNGGCSQRC-VDTPIGYYCDCEKGYKLIDNRTCE 391
K C P F + C E G Q C Y C G + +
Sbjct: 665 YKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS-- 722
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGYARD 424
DI+ECA DP C IC N +GT+KC C++GY D
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVD 757
Score = 41.9 bits (94), Expect = 0.008
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C CIN G+F+C+C G+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGH 277
Score = 41.9 bits (94), Expect = 0.008
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 353 ENECEKNN--GGCSQRCVDTPIGYYCDCEKGYKLID-NRTCEDIDECADPGS-CSQICIN 408
ENEC + GG S C +T Y C C G++ + C+DI+EC + CS N
Sbjct: 2608 ENECLSAHICGGAS--CHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSSN 2665
Query: 409 EKGTFKCECHTGYAR 423
+G + C C GY R
Sbjct: 2666 TEGGYLCGCPPGYFR 2680
Score = 39.5 bits (88), Expect = 0.044
Identities = 15/31 (48%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 392 DIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
D+DEC +P C CIN G+++CEC GY
Sbjct: 2127 DMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC P C+ C N G+FKC C +G+A D +R
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1066
Score = 32.7 bits (71), Expect = 5.0
Identities = 37/133 (27%), Positives = 50/133 (37%), Gaps = 16/133 (12%)
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGS-DEYNCTRQKTICDKRTEF 320
E ++ C GN C Q C++ I G C+ CP G Y + + +
Sbjct: 2566 EDVDECEGNHRC---QHGCQN---IIGGYRCS----CPQGYLQHYQWNQCVDENECLSAH 2615
Query: 321 DCGGGMCIPLSKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCD 377
CGG C + + CP F+ E C + NEC CS +T GY C
Sbjct: 2616 ICGGASCH--NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSSNTEGGYLCG 2673
Query: 378 CEKGYKLIDNRTC 390
C GY I C
Sbjct: 2674 CPPGYFRIGQGHC 2686
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 59.3 bits (137), Expect = 5e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCQ----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 83.0 bits (196), Expect = 4e-15
Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C+ +C G+ C CP G + T + T C+ E G+C
Sbjct: 1082 CARDPLLCRGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1134
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1135 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1194
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1195 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1242
Score = 74.9 bits (176), Expect = 9e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1291 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRG--DC--- 1345
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1346 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1401
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1402 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1444
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2356 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2414
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2415 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2474
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2475 FTCRCPPGFTQHHQACFDNDECSAQPG 2501
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 458 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 515
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 516 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 572
Score = 65.7 bits (153), Expect = 6e-10
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D CI C+ DC + Y CT ++ C+ R E C
Sbjct: 1322 DGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1381
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1382 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1440
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1441 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1486
Score = 64.1 bits (149), Expect = 2e-09
Identities = 103/411 (25%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ Q E C
Sbjct: 1769 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGQNE---CREIP 1820
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1821 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1878
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1879 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1938
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1939 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1998
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1999 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2055
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2056 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2112
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2113 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2163
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2479 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2538
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2539 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2566
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1739 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1796
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1797 KCTRGYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1852
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 995 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1054
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1055 PGSFECECFPGY 1066
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1205 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1264
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1265 KGSFVCHCQLGY 1276
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 402 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 457
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 458 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 515
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 516 EGSFQCVCNAGFELSP-DGKNC 536
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2328 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2387
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2388 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2447
Query: 427 DRTRCK 432
RT CK
Sbjct: 2448 GRT-CK 2452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2438 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2496
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2497 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2524
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 1004 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1061
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1062 CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1109
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 727 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 786
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 787 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 817
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1747 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1795
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G+NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1796 CK----CTRGYKLSPGGACVGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1851
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1852 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1883
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2143 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2200
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2201 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2257
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 465 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 517
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 518 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 577
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 578 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 610
Score = 52.4 bits (120), Expect = 6e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSCSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ G C C N
Sbjct: 1572 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNT 1631
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1632 LGNYTCVCPAEY 1643
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2135 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2194
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2195 YLCTCPAGY 2203
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 735 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 790
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 791 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 850
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 851 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 910
Query: 425 PRDR 428
R
Sbjct: 911 ASGR 914
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2537 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2595
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2596 GGFRCVCPSGFDFD 2609
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 239 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 285
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1569 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1601
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2216 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2275
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2276 VNTAGSFRCDCDEGFQPSP 2294
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2602 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2661
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2662 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2702
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 689 DINECALDPEVCANGVCENLRGSYRCVCNLGY 720
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 992 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1031
Score = 32.7 bits (71), Expect = 5.0
Identities = 39/154 (25%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +CIS C DC + C R F C DR C +
Sbjct: 1324 FECHDLDECISQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1379
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1380 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1435
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1436 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1464
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 81.4 bits (192), Expect = 1e-14
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Query: 341 PNFEDEPRDRCGENECEKN--NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P ++ E + +ECE + NGGC C++ P Y C C G+ L D C D+DEC
Sbjct: 63 PGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQ 122
Query: 398 D-PGSCSQICINEKGTFKCECHTGY 421
D G C QIC+N G+++C+CH+G+
Sbjct: 123 DNNGGCQQICVNAMGSYECQCHSGF 147
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP---GSCSQICIN 408
+EC + C C +TP Y C C+ GYK + + CEDIDEC + G C CIN
Sbjct: 35 DECSEGTDDCHIDAICQNTPKSYKCLCKPGYK-GEGKQCEDIDECENDYYNGGCVHECIN 93
Query: 409 EKGTFKCECHTGY 421
G ++C C G+
Sbjct: 94 IPGNYRCTCFDGF 106
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC-----EDIDECADPGSCSQIC- 406
+EC+ NNGGC Q CV+ Y C C G+ L DN+ TC E ++ C+ IC
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICR 178
Query: 407 INEKGTFKCECHTGY--ARDPRDRT 429
KG C+C G+ A++ +D T
Sbjct: 179 ETPKGGVACDCRPGFDLAQNQKDCT 203
Score = 46.0 bits (104), Expect = 5e-04
Identities = 56/231 (24%), Positives = 84/231 (36%), Gaps = 33/231 (14%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTP-KVRSPCISTEFECNDRITCVHRA 247
+C DG ++ H DVD C D G + CV+ C S F +++ TC+HR+
Sbjct: 101 TCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRS 160
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCP------D 300
E +G V C C PG KDC +
Sbjct: 161 NEGMNCMNKDHGCAHICRETPKGGVAC----------DCRPGFDLAQNQKDCTLTCNYGN 210
Query: 301 GSDEYNCTRQKTI----CDKRTEFDCGGGMCIPLSKVCDKH-----VDCPNFEDEPRDRC 351
G +++C T C ++ G CI + + + + + R
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNATSVADVDKRVKRRL 270
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTC--EDIDECADP 399
C NNGGC + C DT G C C G+ L D +TC + ++ C P
Sbjct: 271 LMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKGQHVELCGCP 321
Score = 41.5 bits (93), Expect = 0.011
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 1/75 (1%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFK 414
C + GC+ C +TP G CDC G+ L N+ + G C C +
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPT 225
Query: 415 CECHTGYARDPRDRT 429
C CH YA RT
Sbjct: 226 CGCHQKYALHSDGRT 240
>L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific
protein protein.
Length = 678
Score = 81.0 bits (191), Expect = 1e-14
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEKG 411
NEC + NGGC Q C + P ++C C G++L D RTC+DIDECAD +C + C N G
Sbjct: 158 NECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPG 217
Query: 412 TFKCECHTGYARDPRDR 428
++ C C G+A +++
Sbjct: 218 SYSCLCDEGFAYSSQEK 234
Score = 62.5 bits (145), Expect = 5e-09
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQK----TICDKRTEFDCG--GGMCIPL--SKVCDK 336
C P G + C D + C + +CDK +C G C+ + +K
Sbjct: 120 CTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVN-ECSQENGGCLQICHNKPGSF 178
Query: 337 HVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H C + FE R C + +EC + RC + P Y C C++G+ + C D
Sbjct: 179 HCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRD 238
Query: 393 IDECADPGSCSQICINEKGTFKCEC 417
+DEC G C Q+C+N G++ C C
Sbjct: 239 VDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 349 DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE-DIDECA-DPGSCSQIC 406
D+C N C++ +Q C D ++C C+ G+ R C+ D++EC+ + G C QIC
Sbjct: 118 DQCTPNPCDRKG---TQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQIC 171
Query: 407 INEKGTFKCECHTGYARDPRDRT 429
N+ G+F C CH+G+ RT
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRT 194
Score = 41.1 bits (92), Expect = 0.014
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL----SKVCDKHVDCPN 342
PG+ +C+ SD C D CG C L S +CD+ +
Sbjct: 175 PGSFHCSCHSGFELSSDGRTCQDIDECADSEA---CGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 343 FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE--KGYKLI-DNRTCEDIDEC 396
E RD +EC + G C Q CV++P Y C C+ G KL D TCEDI C
Sbjct: 232 QEKACRD---VDECLQ--GRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 81.0 bits (191), Expect = 1e-14
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEKG 411
NEC + NGGC Q C + P ++C C G++L D RTC+DIDECAD +C + C N G
Sbjct: 158 NECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPG 217
Query: 412 TFKCECHTGYARDPRDR 428
++ C C G+A +++
Sbjct: 218 SYSCLCDEGFAYSSQEK 234
Score = 62.5 bits (145), Expect = 5e-09
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQK----TICDKRTEFDCG--GGMCIPL--SKVCDK 336
C P G + C D + C + +CDK +C G C+ + +K
Sbjct: 120 CTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVN-ECSQENGGCLQICHNKPGSF 178
Query: 337 HVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H C + FE R C + +EC + RC + P Y C C++G+ + C D
Sbjct: 179 HCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRD 238
Query: 393 IDECADPGSCSQICINEKGTFKCEC 417
+DEC G C Q+C+N G++ C C
Sbjct: 239 VDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 349 DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE-DIDECA-DPGSCSQIC 406
D+C N C++ +Q C D ++C C+ G+ R C+ D++EC+ + G C QIC
Sbjct: 118 DQCTPNPCDRKG---TQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQIC 171
Query: 407 INEKGTFKCECHTGYARDPRDRT 429
N+ G+F C CH+G+ RT
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRT 194
Score = 41.1 bits (92), Expect = 0.014
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL----SKVCDKHVDCPN 342
PG+ +C+ SD C D CG C L S +CD+ +
Sbjct: 175 PGSFHCSCHSGFELSSDGRTCQDIDECADSEA---CGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 343 FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE--KGYKLI-DNRTCEDIDEC 396
E RD +EC + G C Q CV++P Y C C+ G KL D TCEDI C
Sbjct: 232 QEKACRD---VDECLQ--GRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific 6
protein.
Length = 678
Score = 81.0 bits (191), Expect = 1e-14
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEKG 411
NEC + NGGC Q C + P ++C C G++L D RTC+DIDECAD +C + C N G
Sbjct: 158 NECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPG 217
Query: 412 TFKCECHTGYARDPRDR 428
++ C C G+A +++
Sbjct: 218 SYSCLCDEGFAYSSQEK 234
Score = 62.5 bits (145), Expect = 5e-09
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQK----TICDKRTEFDCG--GGMCIPL--SKVCDK 336
C P G + C D + C + +CDK +C G C+ + +K
Sbjct: 120 CTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVN-ECSQENGGCLQICHNKPGSF 178
Query: 337 HVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H C + FE R C + +EC + RC + P Y C C++G+ + C D
Sbjct: 179 HCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRD 238
Query: 393 IDECADPGSCSQICINEKGTFKCEC 417
+DEC G C Q+C+N G++ C C
Sbjct: 239 VDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 349 DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE-DIDECA-DPGSCSQIC 406
D+C N C++ +Q C D ++C C+ G+ R C+ D++EC+ + G C QIC
Sbjct: 118 DQCTPNPCDRKG---TQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQIC 171
Query: 407 INEKGTFKCECHTGYARDPRDRT 429
N+ G+F C CH+G+ RT
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRT 194
Score = 41.1 bits (92), Expect = 0.014
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL----SKVCDKHVDCPN 342
PG+ +C+ SD C D CG C L S +CD+ +
Sbjct: 175 PGSFHCSCHSGFELSSDGRTCQDIDECADSEA---CGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 343 FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE--KGYKLI-DNRTCEDIDEC 396
E RD +EC + G C Q CV++P Y C C+ G KL D TCEDI C
Sbjct: 232 QEKACRD---VDECLQ--GRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specific 6
protein.
Length = 678
Score = 81.0 bits (191), Expect = 1e-14
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEKG 411
NEC + NGGC Q C + P ++C C G++L D RTC+DIDECAD +C + C N G
Sbjct: 158 NECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPG 217
Query: 412 TFKCECHTGYARDPRDR 428
++ C C G+A +++
Sbjct: 218 SYSCLCDEGFAYSSQEK 234
Score = 62.5 bits (145), Expect = 5e-09
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQK----TICDKRTEFDCG--GGMCIPL--SKVCDK 336
C P G + C D + C + +CDK +C G C+ + +K
Sbjct: 120 CTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVN-ECSQENGGCLQICHNKPGSF 178
Query: 337 HVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H C + FE R C + +EC + RC + P Y C C++G+ + C D
Sbjct: 179 HCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRD 238
Query: 393 IDECADPGSCSQICINEKGTFKCEC 417
+DEC G C Q+C+N G++ C C
Sbjct: 239 VDECLQ-GRCEQVCVNSPGSYTCHC 262
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 349 DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE-DIDECA-DPGSCSQIC 406
D+C N C++ +Q C D ++C C+ G+ R C+ D++EC+ + G C QIC
Sbjct: 118 DQCTPNPCDRKG---TQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQIC 171
Query: 407 INEKGTFKCECHTGYARDPRDRT 429
N+ G+F C CH+G+ RT
Sbjct: 172 HNKPGSFHCSCHSGFELSSDGRT 194
Score = 41.1 bits (92), Expect = 0.014
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL----SKVCDKHVDCPN 342
PG+ +C+ SD C D CG C L S +CD+ +
Sbjct: 175 PGSFHCSCHSGFELSSDGRTCQDIDECADSEA---CGEARCKNLPGSYSCLCDEGFAYSS 231
Query: 343 FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE--KGYKLI-DNRTCEDIDEC 396
E RD +EC + G C Q CV++P Y C C+ G KL D TCEDI C
Sbjct: 232 QEKACRD---VDECLQ--GRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 283
>AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens
cDNA FLJ44569 fis, clone UTERU3009979, highly similar
to Homo sapiens growth arrest-specific 6 (GAS6). ).
Length = 624
Score = 81.0 bits (191), Expect = 1e-14
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQI-CINEKG 411
NEC + NGGC Q C + P ++C C G++L D RTC+DIDECAD +C + C N G
Sbjct: 104 NECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPG 163
Query: 412 TFKCECHTGYARDPRDR 428
++ C C G+A +++
Sbjct: 164 SYSCLCDEGFAYSSQEK 180
Score = 62.5 bits (145), Expect = 5e-09
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQK----TICDKRTEFDCG--GGMCIPL--SKVCDK 336
C P G + C D + C + +CDK +C G C+ + +K
Sbjct: 66 CTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVN-ECSQENGGCLQICHNKPGSF 124
Query: 337 HVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
H C + FE R C + +EC + RC + P Y C C++G+ + C D
Sbjct: 125 HCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRD 184
Query: 393 IDECADPGSCSQICINEKGTFKCEC 417
+DEC G C Q+C+N G++ C C
Sbjct: 185 VDECLQ-GRCEQVCVNSPGSYTCHC 208
Score = 61.3 bits (142), Expect = 1e-08
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 349 DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE-DIDECA-DPGSCSQIC 406
D+C N C++ +Q C D ++C C+ G+ R C+ D++EC+ + G C QIC
Sbjct: 64 DQCTPNPCDRKG---TQACQDLMGNFFCLCKAGW---GGRLCDKDVNECSQENGGCLQIC 117
Query: 407 INEKGTFKCECHTGYARDPRDRT 429
N+ G+F C CH+G+ RT
Sbjct: 118 HNKPGSFHCSCHSGFELSSDGRT 140
Score = 41.1 bits (92), Expect = 0.014
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 15/117 (12%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL----SKVCDKHVDCPN 342
PG+ +C+ SD C D CG C L S +CD+ +
Sbjct: 121 PGSFHCSCHSGFELSSDGRTCQDIDECADSEA---CGEARCKNLPGSYSCLCDEGFAYSS 177
Query: 343 FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE--KGYKLI-DNRTCEDIDEC 396
E RD +EC + G C Q CV++P Y C C+ G KL D TCEDI C
Sbjct: 178 QEKACRD---VDECLQ--GRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPC 229
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 81.0 bits (191), Expect = 1e-14
Identities = 54/168 (32%), Positives = 74/168 (44%), Gaps = 18/168 (10%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP- 329
C D C +C G+ C CP G + T + T C+ E G+C
Sbjct: 1075 CARDPLLCWGGTCTNTDGSYKCQ----CPPG---HELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 330 --LSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
++ + C F+ P R C + NEC NGGC C++T Y C C +GY L
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 385 I-DNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
+ D R C D+DEC + P C Q C N G +C C+ G+ P RT
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRT 1235
Score = 75.4 bits (177), Expect = 7e-13
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 20/163 (12%)
Query: 273 CRLDQFQCKDH-SC--IPGALYCN----GVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
C + C H SC IPG+ C V D + D C Q+ C R DC
Sbjct: 1284 CEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG--DC--- 1338
Query: 326 MCIPLSK--VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ +P S C + F E RD C EN +NG +C++ P GY C+CE G+
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG----QCLNAPGGYRCECEMGFD 1394
Query: 384 LI-DNRTCEDIDECADPGSCS-QICINEKGTFKCECHTGYARD 424
D+R C+D+DECA C+ C N G F+C C+ GY D
Sbjct: 1395 PTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 296 KDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-N 354
K CP GS R C C G CI H D C + +
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 355 ECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD-PGSCSQICINEKGT 412
EC + C+ C +T + C C +GY L D RTC+D+DEC +C +C+N G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 413 FKCECHTGYARDPR---DRTRCKATEG 436
F C C G+ + + D C A G
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 315 DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDT 370
D+ T C G C+ + H C P F+ P R C + +EC + G C RCV+T
Sbjct: 451 DECTSSPCHHGDCVNIPGTY--HCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 371 PIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
+ C C G++L D + C D +ECA C + +C+NE G+F C C G+ P
Sbjct: 509 EGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Score = 65.3 bits (152), Expect = 8e-10
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTI------CDKRTEFD-----CG 323
D F+C D C+ C+ DC + Y CT ++ C+ R E C
Sbjct: 1315 DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 324 GGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKG 381
G C+ P C+ + ED R +EC + N C + P + C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDH-RACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 382 YKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
Y+L C DI+ECADP +C + +CIN G++ C C + +P
Sbjct: 1434 YELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Score = 64.1 bits (149), Expect = 2e-09
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 340 CPNFEDEPRDRCGEN-ECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDN-RTCEDIDE 395
CP + C +N EC G C C +TP + C+C +G+ L+ + CED++E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 396 CADPGSCSQICINEKGTFKCECHTGYAR 423
C P C C N+ G ++C C G+ +
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQ 2559
Score = 62.5 bits (145), Expect = 5e-09
Identities = 102/411 (24%), Positives = 143/411 (34%), Gaps = 59/411 (14%)
Query: 54 EDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCDATAD---CPDGSDEHQCEVEACGPEE 110
ED C + + CQ+ +C++ IP S+RC T P G+ + E C
Sbjct: 1762 EDVDECGSRESPCQQ-NADCIN----IPGSYRCKCTRGYKLSPGGACVGRNE---CREIP 1813
Query: 111 FTCRGKPGECVPL--TWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXX 168
C G+C+ ++MC + +D+ C + D CGNG C +
Sbjct: 1814 NVC--SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCL 1871
Query: 169 XX-XXXXXXEVKCPT-PTCQPQSHFSCTDGQCISAW--WHC---DGDVDCADGSDEVG-- 219
C C C G C++ +HC DG ADG + V
Sbjct: 1872 CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 220 -CVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCR-GNVTCRLDQ 277
C+S P E + R C V E LC G T
Sbjct: 1932 ECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGS 1991
Query: 278 FQCKDHSCIPGALYCNGVKDCPDGSDEY----------------NCTRQKTICDKRTEFD 321
FQC C PG + + C D + N T+ + C KR
Sbjct: 1992 FQCL---CPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEG 2048
Query: 322 CGGG--MC-----IPLSKVCD-KHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDTPI 372
G +C ++C H P +D D NEC +N G C+ CV+T
Sbjct: 2049 WGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED---VNECAENPGVCTNGVCVNTDG 2105
Query: 373 GYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGY 421
+ C+C GY L C D DEC+ C Q C N G F+C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFEDEPRDRCGENECEKNNGGCSQR--CVDTPIGYYC 376
C G+CI +++ +CP N+ +EC C Q C++ P Y C
Sbjct: 1732 CANGICI--NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC 1789
Query: 377 DCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRC 431
C +GYKL C +EC + P CS C++ +G++ C CH G+ + D+T C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLC 1845
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINE 409
NEC+ G C+ C +T ++C C G+ L R C DIDEC P C Q C+N
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNT 1047
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1048 PGSFECECFPGY 1059
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINE 409
+ECE+N C Q C + P G+ C C G+ D RTC D+DEC +P C C N
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENT 1257
Query: 410 KGTFKCECHTGY 421
KG+F C C GY
Sbjct: 1258 KGSFVCHCQLGY 1269
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 299 PDGSDEYNCTRQKTI--CDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFEDEPRDRCGE- 353
P S+ T +TI C T C G C+P S C+ +V + + R C +
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNL-CLNGRCLPTPSSYRCECNV---GYTQDVRGECIDV 450
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADPGSCSQI--CINE 409
+EC + C CV+ P Y+C C G++ R C D+DEC G + C+N
Sbjct: 451 DEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNT 508
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F+C C+ G+ P D C
Sbjct: 509 EGSFQCVCNAGFELSP-DGKNC 529
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 317 RTEFDCGGGM-----C--IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCV 368
R E CGGG C PL CP+ + +EC C+ C+
Sbjct: 2321 RAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 369 DTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTFKCECHTGYARDPR 426
++ + C C+ GY TC D+DEC+ P C+ +C N KG+F C C GY +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEED 2440
Query: 427 DRTRCK 432
RT CK
Sbjct: 2441 GRT-CK 2445
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 340 CPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC 396
CP E++ R +EC C CV+T + C C G+ ++ C D DEC
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ-HHQACFDNDEC 2489
Query: 397 -ADPGSCSQ--ICINEKGTFKCECHTGY 421
A PG C C N G+F+CECH G+
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C G C + V H C F + ++R C + +EC + C Q CV+TP + C+
Sbjct: 997 CTHGTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE 1054
Query: 378 CEKGYK--LIDNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
C GY+ + + C D+DECA DP C C N G++KC+C G+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGH 1102
Score = 55.6 bits (128), Expect = 6e-07
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 348 RDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQI 405
+D +EC N+ C C ++P Y C C G+ D C+D+DEC S +
Sbjct: 720 KDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV 779
Query: 406 CINEKGTFKCECHTGYARDPRDRTRCKATEG 436
C N G++ C+C G DP +T+G
Sbjct: 780 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKG 810
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 19/152 (12%)
Query: 274 RLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
++ F+C+ C G Y + + C D DE C +++ C + DC + IP S
Sbjct: 1740 QIGSFRCE---CPAGFNYNSILLACED-VDE--CGSRESPCQQNA--DC---INIPGSYR 1788
Query: 334 CDKHVDCPN-FEDEPRDRC-GENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDNRT- 389
C C ++ P C G NEC + CS C+DT Y C C +G++ ++T
Sbjct: 1789 CK----CTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 390 CEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C DIDEC + C N G++ C C G+
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/117 (34%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCE 379
CG G C + + C + FE C + +EC N C+ RC +T Y C C
Sbjct: 2136 CGQGTCTNV--IGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 380 KGYKL-IDNRTCEDIDECAD-PGSC---SQICINEKGTFKCECHTGYARDPRDRTRC 431
GY L D C D+DECAD C C N GTF C C G P C
Sbjct: 2194 AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 17/153 (11%)
Query: 280 CKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC-IPLSKVCDK 336
C C IPG +C C G + T + C E GG+C + +
Sbjct: 458 CHHGDCVNIPGTYHCR----CYPG---FQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 337 HVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
C FE P + C + NEC + + C++ + C C+ G+ L C
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Query: 391 EDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
DIDEC PG C + C N +G+F+C+C G A
Sbjct: 571 MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 52.0 bits (119), Expect = 8e-06
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGS-CSQ-ICINE 409
+EC++ G C CV+T + C+C GY L ++ R CEDIDEC+ S C C N
Sbjct: 1565 DECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNT 1624
Query: 410 KGTFKCECHTGY 421
G + C C Y
Sbjct: 1625 LGNYTCVCPAEY 1636
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C + G+ C C G++ TCEDIDEC+ +P C+ C N +G+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGS 2187
Query: 413 FKCECHTGY 421
+ C C GY
Sbjct: 2188 YLCTCPAGY 2196
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/184 (28%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L+ C + C PG+ C+ CP G + T D+ C G+C L
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCS----CPPGFHFWQDTEICKDVDECLSSPCVSGVCRNL 783
Query: 331 --SKVCD----KHVDCPNFE--DEPRDRCG----ENECEKNNGGCSQR--CVDT---PIG 373
S C +D D + C E+ CE N G S R C T G
Sbjct: 784 AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWG 843
Query: 374 YYCD-------CEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARD 424
C+ C +G+ + TC+D++EC PG C C+N G+F+CEC G D
Sbjct: 844 SPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 425 PRDR 428
R
Sbjct: 904 ASGR 907
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICINEK 410
NEC+ + C C + GY C C +G+ C D +ECA P +C S C N
Sbjct: 2530 NECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Query: 411 GTFKCECHTGYARD 424
G F+C C +G+ D
Sbjct: 2589 GGFRCVCPSGFDFD 2602
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C C+N G+F C C G+
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Score = 40.3 bits (90), Expect = 0.025
Identities = 18/33 (54%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGY 421
EDIDEC + PG C C+N G+F+CEC GY
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 40.3 bits (90), Expect = 0.025
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 354 NECEKNNGGCSQRCVDTP--IGYY-CDCEKGYKLI--DNRTCEDIDEC-ADPGSC-SQIC 406
+EC C R ++ IG + C C G + + C D +EC A P C + C
Sbjct: 2209 DECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRC 2268
Query: 407 INEKGTFKCECHTGYARDP 425
+N G+F+C+C G+ P
Sbjct: 2269 VNTAGSFRCDCDEGFQPSP 2287
Score = 39.9 bits (89), Expect = 0.033
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 340 CPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTC-EDIDE 395
CP+ F+ D+ C + +EC G CS C +TP G+ C C +GY C +
Sbjct: 2595 CPSGFDFDQALGGCQDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLGF 2654
Query: 396 CADPGSC--SQICINEKGTFKCECHTGYARDPRDRTRCKATEGH 437
P + ++ + ++C+ + PRDR R A H
Sbjct: 2655 SPGPQDTPDKEELLSSEACYECKIN---GLSPRDRPRRSAHRDH 2695
Score = 36.7 bits (81), Expect = 0.31
Identities = 15/32 (46%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGY 421
DI+ECA DP C+ +C N +G+++C C+ GY
Sbjct: 682 DINECALDPEVCANGVCENLRGSYRCVCNLGY 713
Score = 35.5 bits (78), Expect = 0.71
Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+D++EC PG C+ C N G+F C C G+A D ++R
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Score = 32.3 bits (70), Expect = 6.6
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 15/154 (9%)
Query: 191 FSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWV 249
F C D +C+S C DC + C R F C DR C +
Sbjct: 1317 FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTC----RQGFAGDGFFCEDRDECAENVDL 1372
Query: 250 XXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCT 308
E C D C+D C G L G C + + C
Sbjct: 1373 CDNGQCLNAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRC- 1428
Query: 309 RQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPN 342
IC+ E D GGG C +++ C V+C N
Sbjct: 1429 ----ICNGGYELDRGGGNCTDINE-CADPVNCIN 1457
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 79.8 bits (188), Expect = 3e-14
Identities = 67/247 (27%), Positives = 100/247 (40%), Gaps = 22/247 (8%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTPKVRSPCISTEFECND-RITCVHRA 247
+C DG ++ H DVD C + G + CV+ C F +D + TC+HR+
Sbjct: 112 TCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRS 171
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLD---QFQCKDHSCIPGALYCNG--VKDCPDG 301
E RG+V C + CI + NG C D
Sbjct: 172 EEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDT 231
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIP----LSKVCDKHV-DCPNFEDEPRDRCGENEC 356
+D C+ C + + G C+ + +V + + + + + R C
Sbjct: 232 ADGPECS-----CHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETC 286
Query: 357 EKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFK 414
NNGGC + C DT G +C C G+ L +D +TC+DIDEC G C C N G+F
Sbjct: 287 AVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD 346
Query: 415 CECHTGY 421
C C G+
Sbjct: 347 CGCKKGF 353
Score = 79.8 bits (188), Expect = 3e-14
Identities = 30/69 (43%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
+EC+ NGGC C + + C C+KG+KL+ D ++C+D+DEC+ +C CIN GT
Sbjct: 325 DECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGT 384
Query: 413 FKCECHTGY 421
F C C+ GY
Sbjct: 385 FACACNRGY 393
Score = 66.1 bits (154), Expect = 4e-10
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKN-NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD 398
P ++ E R +EC NGGC C++ P Y C C G+ L D C D+DEC +
Sbjct: 75 PGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLE 134
Query: 399 -PGSCSQICINEKGTFKCECHTGY 421
G C C+N G+++C C G+
Sbjct: 135 NNGGCQHTCVNVMGSYECCCKEGF 158
Score = 65.7 bits (153), Expect = 6e-10
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C C++ P + C C +GY L C D +EC+ + G C Q+C+N G+
Sbjct: 366 DECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGS 424
Query: 413 FKCECHTGY 421
++C+CH GY
Sbjct: 425 YECQCHPGY 433
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINE 409
+EC + C C +TP Y C C+ GY+ + R CEDIDEC + G C C+N
Sbjct: 47 DECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCVHDCLNI 105
Query: 410 KGTFKCECHTGY 421
G ++C C G+
Sbjct: 106 PGNYRCTCFDGF 117
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/83 (38%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC----EDIDECADPG-SCSQICI 407
+EC +NNGGC CV+ Y C C++G+ L DN+ TC E+ C + CS IC
Sbjct: 130 DECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICK 189
Query: 408 N-EKGTFKCECHTGY--ARDPRD 427
+G+ CEC G+ A++ RD
Sbjct: 190 EAPRGSVACECRPGFELAKNQRD 212
Score = 50.8 bits (116), Expect = 2e-05
Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR 388
CG+ NEC NNGGC Q CV+T Y C C GYKL N+
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 33.5 bits (73), Expect = 2.9
Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 391 EDIDECA---DPGSCSQICINEKGTFKCECHTGYARDPR 426
ED+DECA D +C N ++KC C GY + R
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR 82
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 79.8 bits (188), Expect = 3e-14
Identities = 30/69 (43%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
+EC+ NGGC C + + C C+KG+KL+ D ++C+D+DEC+ +C CIN GT
Sbjct: 325 DECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGT 384
Query: 413 FKCECHTGY 421
F C C+ GY
Sbjct: 385 FACACNRGY 393
Score = 78.2 bits (184), Expect = 1e-13
Identities = 66/247 (26%), Positives = 97/247 (39%), Gaps = 22/247 (8%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTPKVRSPCISTEFECND-RITCVHRA 247
+C DG ++ H DVD C + G + CV+ C F +D + TC+HR+
Sbjct: 112 TCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRS 171
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLD---QFQCKDHSCIPGALYCNG--VKDCPDG 301
E RG+V C + CI + NG C D
Sbjct: 172 EEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDT 231
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE-----C 356
+D C+ C + + G C+ + + D+ + + C
Sbjct: 232 ADGPECS-----CHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRQLLMETC 286
Query: 357 EKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFK 414
NNGGC + C DT G +C C G+ L +D +TC+DIDEC G C C N G+F
Sbjct: 287 AVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD 346
Query: 415 CECHTGY 421
C C G+
Sbjct: 347 CGCKKGF 353
Score = 66.1 bits (154), Expect = 4e-10
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKN-NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD 398
P ++ E R +EC NGGC C++ P Y C C G+ L D C D+DEC +
Sbjct: 75 PGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLE 134
Query: 399 -PGSCSQICINEKGTFKCECHTGY 421
G C C+N G+++C C G+
Sbjct: 135 NNGGCQHTCVNVMGSYECCCKEGF 158
Score = 65.7 bits (153), Expect = 6e-10
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C C++ P + C C +GY L C D +EC+ + G C Q+C+N G+
Sbjct: 366 DECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGS 424
Query: 413 FKCECHTGY 421
++C+CH GY
Sbjct: 425 YECQCHPGY 433
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINE 409
+EC + C C +TP Y C C+ GY+ + R CEDIDEC + G C C+N
Sbjct: 47 DECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCVHDCLNI 105
Query: 410 KGTFKCECHTGY 421
G ++C C G+
Sbjct: 106 PGNYRCTCFDGF 117
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/83 (38%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC----EDIDECADPG-SCSQICI 407
+EC +NNGGC CV+ Y C C++G+ L DN+ TC E+ C + CS IC
Sbjct: 130 DECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICK 189
Query: 408 N-EKGTFKCECHTGY--ARDPRD 427
+G+ CEC G+ A++ RD
Sbjct: 190 EAPRGSVACECRPGFELAKNQRD 212
Score = 50.8 bits (116), Expect = 2e-05
Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR 388
CG+ NEC NNGGC Q CV+T Y C C GYKL N+
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 33.5 bits (73), Expect = 2.9
Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 391 EDIDECA---DPGSCSQICINEKGTFKCECHTGYARDPR 426
ED+DECA D +C N ++KC C GY + R
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR 82
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 79.8 bits (188), Expect = 3e-14
Identities = 67/247 (27%), Positives = 100/247 (40%), Gaps = 22/247 (8%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTPKVRSPCISTEFECND-RITCVHRA 247
+C DG ++ H DVD C + G + CV+ C F +D + TC+HR+
Sbjct: 112 TCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRS 171
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLD---QFQCKDHSCIPGALYCNG--VKDCPDG 301
E RG+V C + CI + NG C D
Sbjct: 172 EEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDT 231
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIP----LSKVCDKHV-DCPNFEDEPRDRCGENEC 356
+D C+ C + + G C+ + +V + + + + + R C
Sbjct: 232 ADGPECS-----CHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETC 286
Query: 357 EKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFK 414
NNGGC + C DT G +C C G+ L +D +TC+DIDEC G C C N G+F
Sbjct: 287 AVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD 346
Query: 415 CECHTGY 421
C C G+
Sbjct: 347 CGCKKGF 353
Score = 79.8 bits (188), Expect = 3e-14
Identities = 30/69 (43%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
+EC+ NGGC C + + C C+KG+KL+ D ++C+D+DEC+ +C CIN GT
Sbjct: 325 DECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGT 384
Query: 413 FKCECHTGY 421
F C C+ GY
Sbjct: 385 FACACNRGY 393
Score = 66.1 bits (154), Expect = 4e-10
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKN-NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD 398
P ++ E R +EC NGGC C++ P Y C C G+ L D C D+DEC +
Sbjct: 75 PGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLE 134
Query: 399 -PGSCSQICINEKGTFKCECHTGY 421
G C C+N G+++C C G+
Sbjct: 135 NNGGCQHTCVNVMGSYECCCKEGF 158
Score = 65.7 bits (153), Expect = 6e-10
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C C++ P + C C +GY L C D +EC+ + G C Q+C+N G+
Sbjct: 366 DECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGS 424
Query: 413 FKCECHTGY 421
++C+CH GY
Sbjct: 425 YECQCHPGY 433
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINE 409
+EC + C C +TP Y C C+ GY+ + R CEDIDEC + G C C+N
Sbjct: 47 DECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCVHDCLNI 105
Query: 410 KGTFKCECHTGY 421
G ++C C G+
Sbjct: 106 PGNYRCTCFDGF 117
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/83 (38%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC----EDIDECADPG-SCSQICI 407
+EC +NNGGC CV+ Y C C++G+ L DN+ TC E+ C + CS IC
Sbjct: 130 DECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICK 189
Query: 408 N-EKGTFKCECHTGY--ARDPRD 427
+G+ CEC G+ A++ RD
Sbjct: 190 EAPRGSVACECRPGFELAKNQRD 212
Score = 50.8 bits (116), Expect = 2e-05
Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR 388
CG+ NEC NNGGC Q CV+T Y C C GYKL N+
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 33.5 bits (73), Expect = 2.9
Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 391 EDIDECA---DPGSCSQICINEKGTFKCECHTGYARDPR 426
ED+DECA D +C N ++KC C GY + R
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR 82
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 79.8 bits (188), Expect = 3e-14
Identities = 67/247 (27%), Positives = 100/247 (40%), Gaps = 22/247 (8%)
Query: 192 SCTDGQCISAWWHCDGDVD-CAD--GSDEVGCVSTPKVRSPCISTEFECND-RITCVHRA 247
+C DG ++ H DVD C + G + CV+ C F +D + TC+HR+
Sbjct: 112 TCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRS 171
Query: 248 WVXXXXXXXXXXXXEAL-ELCRGNVTCRLD---QFQCKDHSCIPGALYCNG--VKDCPDG 301
E RG+V C + CI + NG C D
Sbjct: 172 EEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDT 231
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGMCIP----LSKVCDKHV-DCPNFEDEPRDRCGENEC 356
+D C+ C + + G C+ + +V + + + + + R C
Sbjct: 232 ADGPECS-----CHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETC 286
Query: 357 EKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFK 414
NNGGC + C DT G +C C G+ L +D +TC+DIDEC G C C N G+F
Sbjct: 287 AVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD 346
Query: 415 CECHTGY 421
C C G+
Sbjct: 347 CGCKKGF 353
Score = 79.8 bits (188), Expect = 3e-14
Identities = 30/69 (43%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGT 412
+EC+ NGGC C + + C C+KG+KL+ D ++C+D+DEC+ +C CIN GT
Sbjct: 325 DECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGT 384
Query: 413 FKCECHTGY 421
F C C+ GY
Sbjct: 385 FACACNRGY 393
Score = 66.1 bits (154), Expect = 4e-10
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 341 PNFEDEPRDRCGENECEKN-NGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECAD 398
P ++ E R +EC NGGC C++ P Y C C G+ L D C D+DEC +
Sbjct: 75 PGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLE 134
Query: 399 -PGSCSQICINEKGTFKCECHTGY 421
G C C+N G+++C C G+
Sbjct: 135 NNGGCQHTCVNVMGSYECCCKEGF 158
Score = 65.7 bits (153), Expect = 6e-10
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGT 412
+EC + C C++ P + C C +GY L C D +EC+ + G C Q+C+N G+
Sbjct: 366 DECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGS 424
Query: 413 FKCECHTGY 421
++C+CH GY
Sbjct: 425 YECQCHPGY 433
Score = 60.1 bits (139), Expect = 3e-08
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP--GSCSQICINE 409
+EC + C C +TP Y C C+ GY+ + R CEDIDEC + G C C+N
Sbjct: 47 DECAQGLDDCHADALCQNTPTSYKCSCKPGYQ-GEGRQCEDIDECGNELNGGCVHDCLNI 105
Query: 410 KGTFKCECHTGY 421
G ++C C G+
Sbjct: 106 PGNYRCTCFDGF 117
Score = 56.4 bits (130), Expect = 4e-07
Identities = 32/83 (38%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR-TC----EDIDECADPG-SCSQICI 407
+EC +NNGGC CV+ Y C C++G+ L DN+ TC E+ C + CS IC
Sbjct: 130 DECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICK 189
Query: 408 N-EKGTFKCECHTGY--ARDPRD 427
+G+ CEC G+ A++ RD
Sbjct: 190 EAPRGSVACECRPGFELAKNQRD 212
Score = 50.8 bits (116), Expect = 2e-05
Identities = 22/39 (56%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 351 CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNR 388
CG+ NEC NNGGC Q CV+T Y C C GYKL N+
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 33.5 bits (73), Expect = 2.9
Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 391 EDIDECA---DPGSCSQICINEKGTFKCECHTGYARDPR 426
ED+DECA D +C N ++KC C GY + R
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR 82
>BC113716-1|AAI13717.1| 713|Homo sapiens low density lipoprotein
receptor-related protein 10 protein.
Length = 713
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 34 RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-----CIPRSWRCDA 88
RC + +CD DC+D +DE+ C C F C + G C + RC+
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEED--CPG----CPPGHFPCGAAGTSGATACYLPADRCNY 383
Query: 89 TADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C DG+DE +C C P F CR + +CV TW+CD PDC+DGSDE C+
Sbjct: 384 QTFCADGADERRCR--HCQPGNFRCRDE--KCVYETWVCDGQPDCADGSDEWDCS 434
Score = 62.5 bits (145), Expect = 5e-09
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTC--RGKPGE--CVPLTWMCDDNPDCS 134
C + RCD + DC DG+DE C C P F C G G C C+ C+
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDCP--GCPPGHFPCGAAGTSGATACYLPADRCNYQTFCA 388
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
DG+DE+ C C+ F C + KC+ WV
Sbjct: 389 DGADERRCRH-CQPGNFRCRDEKCVYETWV 417
Score = 62.1 bits (144), Expect = 7e-09
Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+C S CDG DCADG+DE C P PC + + C A
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAG--TSGATACYLPADRCNYQTFC 387
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
E CR C+ F+C+D C+ C+G DC DGSDE++C+
Sbjct: 388 ADGADE--RRCRH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCS 434
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 120 CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG------KCIQMRWVXXXXXXXXX 173
C CD + DC+DG+DE+ C C F CG C
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDC-PGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCAD 389
Query: 174 XXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E +C CQP +F C D +C+ W CDG DCADGSDE C
Sbjct: 390 GADERRCRH--CQP-GNFRCRDEKCVYETWVCDGQPDCADGSDEWDC 433
Score = 46.8 bits (106), Expect = 3e-04
Identities = 19/37 (51%), Positives = 22/37 (59%)
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
Q F C + +C+SA CDG C DGSDE GC S P
Sbjct: 142 QEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDP 178
Score = 44.8 bits (101), Expect = 0.001
Identities = 16/36 (44%), Positives = 22/36 (61%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
C ++FQC +H C+ C+GV C DGSDE C+
Sbjct: 140 CLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
R C FRC+ +C+ +W CD + DC+D SDE
Sbjct: 397 RHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDE 430
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 15 FLFSESRT---CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
FL S S+ C EF+C RC+ +CD C D SDE
Sbjct: 129 FLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDE 171
Score = 35.9 bits (79), Expect = 0.54
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 64 MVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQC 101
++C + F+CL+ C+ RCD C DGSDE C
Sbjct: 138 LMCLQEEFQCLNHR-CVSAVQRCDGVDACGDGSDEAGC 174
Score = 33.5 bits (73), Expect = 2.9
Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C EEF C CV CD C DGSDE C+
Sbjct: 140 CLQEEFQCLNH--RCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 33.5 bits (73), Expect = 2.9
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF 343
+C A CN C DG+DE C C F C C+ + VCD DC +
Sbjct: 373 ACYLPADRCNYQTFCADGADERRCRH----CQPGN-FRCRDEKCVYETWVCDGQPDCADG 427
Query: 344 EDE 346
DE
Sbjct: 428 SDE 430
Score = 32.3 bits (70), Expect = 6.6
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
Query: 183 PTCQPQSHFSC----TDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFE 236
P C P HF C T G C C+ CADG+DE C C F
Sbjct: 354 PGCPP-GHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC-------RHCQPGNFR 405
Query: 237 CNDRITCVHRAWV 249
C D CV+ WV
Sbjct: 406 CRDE-KCVYETWV 417
>BC113714-1|AAI13715.1| 713|Homo sapiens low density lipoprotein
receptor-related protein 10 protein.
Length = 713
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 34 RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-----CIPRSWRCDA 88
RC + +CD DC+D +DE+ C C F C + G C + RC+
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEED--CPG----CPPGHFPCGAAGTSGATACYLPADRCNY 383
Query: 89 TADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C DG+DE +C C P F CR + +CV TW+CD PDC+DGSDE C+
Sbjct: 384 QTFCADGADERRCR--HCQPGNFRCRDE--KCVYETWVCDGQPDCADGSDEWDCS 434
Score = 62.5 bits (145), Expect = 5e-09
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTC--RGKPGE--CVPLTWMCDDNPDCS 134
C + RCD + DC DG+DE C C P F C G G C C+ C+
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDCP--GCPPGHFPCGAAGTSGATACYLPADRCNYQTFCA 388
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
DG+DE+ C C+ F C + KC+ WV
Sbjct: 389 DGADERRCRH-CQPGNFRCRDEKCVYETWV 417
Score = 62.1 bits (144), Expect = 7e-09
Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+C S CDG DCADG+DE C P PC + + C A
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAG--TSGATACYLPADRCNYQTFC 387
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
E CR C+ F+C+D C+ C+G DC DGSDE++C+
Sbjct: 388 ADGADE--RRCRH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCS 434
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 120 CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG------KCIQMRWVXXXXXXXXX 173
C CD + DC+DG+DE+ C C F CG C
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDC-PGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCAD 389
Query: 174 XXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E +C CQP +F C D +C+ W CDG DCADGSDE C
Sbjct: 390 GADERRCRH--CQP-GNFRCRDEKCVYETWVCDGQPDCADGSDEWDC 433
Score = 46.8 bits (106), Expect = 3e-04
Identities = 19/37 (51%), Positives = 22/37 (59%)
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
Q F C + +C+SA CDG C DGSDE GC S P
Sbjct: 142 QEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDP 178
Score = 44.8 bits (101), Expect = 0.001
Identities = 16/36 (44%), Positives = 22/36 (61%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
C ++FQC +H C+ C+GV C DGSDE C+
Sbjct: 140 CLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
R C FRC+ +C+ +W CD + DC+D SDE
Sbjct: 397 RHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDE 430
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 15 FLFSESRT---CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
FL S S+ C EF+C RC+ +CD C D SDE
Sbjct: 129 FLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDE 171
Score = 35.9 bits (79), Expect = 0.54
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 64 MVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQC 101
++C + F+CL+ C+ RCD C DGSDE C
Sbjct: 138 LMCLQEEFQCLNHR-CVSAVQRCDGVDACGDGSDEAGC 174
Score = 33.5 bits (73), Expect = 2.9
Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C EEF C CV CD C DGSDE C+
Sbjct: 140 CLQEEFQCLNH--RCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 33.5 bits (73), Expect = 2.9
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF 343
+C A CN C DG+DE C C F C C+ + VCD DC +
Sbjct: 373 ACYLPADRCNYQTFCADGADERRCRH----CQPGN-FRCRDEKCVYETWVCDGQPDCADG 427
Query: 344 EDE 346
DE
Sbjct: 428 SDE 430
Score = 32.3 bits (70), Expect = 6.6
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
Query: 183 PTCQPQSHFSC----TDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFE 236
P C P HF C T G C C+ CADG+DE C C F
Sbjct: 354 PGCPP-GHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC-------RHCQPGNFR 405
Query: 237 CNDRITCVHRAWV 249
C D CV+ WV
Sbjct: 406 CRDE-KCVYETWV 417
>BC064901-1|AAH64901.1| 457|Homo sapiens LRP10 protein protein.
Length = 457
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 34 RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-----CIPRSWRCDA 88
RC + +CD DC+D +DE+ C C F C + G C + RC+
Sbjct: 231 RCYSEAQRCDGSWDCADGTDEED--CPG----CPPGHFPCGAAGTSGATACYLPADRCNY 284
Query: 89 TADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C DG+DE +C C P F CR + +CV TW+CD PDC+DGSDE C+
Sbjct: 285 QTFCADGADERRCR--HCQPGNFRCRDE--KCVYETWVCDGQPDCADGSDEWDCS 335
Score = 62.5 bits (145), Expect = 5e-09
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTC--RGKPGE--CVPLTWMCDDNPDCS 134
C + RCD + DC DG+DE C C P F C G G C C+ C+
Sbjct: 232 CYSEAQRCDGSWDCADGTDEEDCP--GCPPGHFPCGAAGTSGATACYLPADRCNYQTFCA 289
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
DG+DE+ C C+ F C + KC+ WV
Sbjct: 290 DGADERRCRH-CQPGNFRCRDEKCVYETWV 318
Score = 62.1 bits (144), Expect = 7e-09
Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+C S CDG DCADG+DE C P PC + + C A
Sbjct: 231 RCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAG--TSGATACYLPADRCNYQTFC 288
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
E CR C+ F+C+D C+ C+G DC DGSDE++C+
Sbjct: 289 ADGADE--RRCRH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCS 335
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 120 CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG------KCIQMRWVXXXXXXXXX 173
C CD + DC+DG+DE+ C C F CG C
Sbjct: 232 CYSEAQRCDGSWDCADGTDEEDC-PGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCAD 290
Query: 174 XXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E +C CQP +F C D +C+ W CDG DCADGSDE C
Sbjct: 291 GADERRCRH--CQP-GNFRCRDEKCVYETWVCDGQPDCADGSDEWDC 334
Score = 46.8 bits (106), Expect = 3e-04
Identities = 19/37 (51%), Positives = 22/37 (59%)
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
Q F C + +C+SA CDG C DGSDE GC S P
Sbjct: 43 QEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDP 79
Score = 44.8 bits (101), Expect = 0.001
Identities = 16/36 (44%), Positives = 22/36 (61%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
C ++FQC +H C+ C+GV C DGSDE C+
Sbjct: 41 CLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCS 76
Score = 44.4 bits (100), Expect = 0.002
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
R C FRC+ +C+ +W CD + DC+D SDE
Sbjct: 298 RHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDE 331
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 15 FLFSESRT---CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
FL S S+ C EF+C RC+ +CD C D SDE
Sbjct: 30 FLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDE 72
Score = 35.9 bits (79), Expect = 0.54
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 64 MVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQC 101
++C + F+CL+ C+ RCD C DGSDE C
Sbjct: 39 LMCLQEEFQCLNHR-CVSAVQRCDGVDACGDGSDEAGC 75
Score = 33.5 bits (73), Expect = 2.9
Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C EEF C CV CD C DGSDE C+
Sbjct: 41 CLQEEFQCLNH--RCVSAVQRCDGVDACGDGSDEAGCS 76
Score = 33.5 bits (73), Expect = 2.9
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF 343
+C A CN C DG+DE C C F C C+ + VCD DC +
Sbjct: 274 ACYLPADRCNYQTFCADGADERRCRH----CQPGN-FRCRDEKCVYETWVCDGQPDCADG 328
Query: 344 EDE 346
DE
Sbjct: 329 SDE 331
Score = 32.3 bits (70), Expect = 6.6
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
Query: 183 PTCQPQSHFSC----TDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFE 236
P C P HF C T G C C+ CADG+DE C C F
Sbjct: 255 PGCPP-GHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC-------RHCQPGNFR 306
Query: 237 CNDRITCVHRAWV 249
C D CV+ WV
Sbjct: 307 CRDE-KCVYETWV 318
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 77.4 bits (182), Expect = 2e-13
Identities = 54/172 (31%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 265 ELCRGNVTCRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC 322
+LC ++ C + C H CI PG+ C + SD+ C R + +C + +C
Sbjct: 235 KLCTAHM-CSTLEHNCA-HFCINIPGSYVCRCKQGYILNSDQTTC-RIQDLCAME-DHNC 290
Query: 323 GGGMCI--PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEK 380
+C+ P S VC + ED R + C N GC CV+ Y C C +
Sbjct: 291 EQ-LCVNVPGSFVCQCYSGYALAEDGKRC-VAVDYCASENHGCEHECVNADGSYLCQCHE 348
Query: 381 GYKLI-DNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
G+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 349 GFALNPDEKTCTRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 399
Score = 72.9 bits (171), Expect = 4e-12
Identities = 41/129 (31%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICIN 408
C + C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN 296
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVND 464
G+F C+C++GYA D RC A + S +H+ + HE A+ D
Sbjct: 297 VPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 465 TKSATALDY 473
K+ T ++Y
Sbjct: 356 EKTCTRINY 364
Score = 72.5 bits (170), Expect = 5e-12
Identities = 48/162 (29%), Positives = 66/162 (40%), Gaps = 17/162 (10%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 276 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 335
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKG 381
S +C H DE C N C N GC CV+ YYC C +G
Sbjct: 336 VNA---DGSYLCQCHEGFALNPDEKT--CTRINYCALNKPGCEHECVNMEESYYCRCHRG 390
Query: 382 YKLIDN-RTCEDIDECADPG-SCSQICINEKGTFKCECHTGY 421
Y L N +TC +D CA C Q+C+N + +F C+C G+
Sbjct: 391 YTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 432
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPG-SCSQICINEKGTF 413
C+ + GC CV++ Y C+C +G++L D + C D C C IC+N ++
Sbjct: 529 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSY 588
Query: 414 KCECHTGYARDPRDRTRC-KATEGHPSLLF 442
C+C G+ D RC K TEG L+F
Sbjct: 589 ICKCSEGFVL-AEDGRRCKKCTEGPIDLVF 617
Score = 58.0 bits (134), Expect = 1e-07
Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 21/177 (11%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNG--VKDCPDG----SDEYNCTRQK--TICDKRTEF 320
G R+D +DH C L V C +G D C+R + D E+
Sbjct: 397 GKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY 456
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCD 377
C + + S C CP D C + + C + GC CV + + C
Sbjct: 457 SC---VNMDRSFACQ----CPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQ 509
Query: 378 CEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C +GY L D +TC D C A C IC+N ++ CEC G+ R D RC+
Sbjct: 510 CFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGF-RLAEDGKRCR 565
>AY358399-1|AAQ88765.1| 713|Homo sapiens LRP10 protein.
Length = 713
Score = 77.4 bits (182), Expect = 2e-13
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 34 RCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-----CIPRSWRCDA 88
RC + +CD DC+D +DE+ C C F C + G C + RC+
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEED--CPG----CPPGHFPCGAAGTSGATACYLPADRCNY 383
Query: 89 TADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C DG+DE +C C P F CR + +CV TW+CD PDC+DGSDE C+
Sbjct: 384 QTFCADGADERRCR--HCQPGNFRCRDE--KCVYETWVCDGQPDCADGSDEWDCS 434
Score = 62.5 bits (145), Expect = 5e-09
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 79 CIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTC--RGKPGE--CVPLTWMCDDNPDCS 134
C + RCD + DC DG+DE C C P F C G G C C+ C+
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDCP--GCPPGHFPCGAAGTSGATACYLPADRCNYQTFCA 388
Query: 135 DGSDEKACNETCRSDEFTCGNGKCIQMRWV 164
DG+DE+ C C+ F C + KC+ WV
Sbjct: 389 DGADERRCRH-CQPGNFRCRDEKCVYETWV 417
Score = 62.1 bits (144), Expect = 7e-09
Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 197 QCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXX 256
+C S CDG DCADG+DE C P PC + + C A
Sbjct: 330 RCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAG--TSGATACYLPADRCNYQTFC 387
Query: 257 XXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
E CR C+ F+C+D C+ C+G DC DGSDE++C+
Sbjct: 388 ADGADE--RRCRH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCS 434
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 120 CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG------KCIQMRWVXXXXXXXXX 173
C CD + DC+DG+DE+ C C F CG C
Sbjct: 331 CYSEAQRCDGSWDCADGTDEEDC-PGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCAD 389
Query: 174 XXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
E +C CQP +F C D +C+ W CDG DCADGSDE C
Sbjct: 390 GADERRCRH--CQP-GNFRCRDEKCVYETWVCDGQPDCADGSDEWDC 433
Score = 46.8 bits (106), Expect = 3e-04
Identities = 19/37 (51%), Positives = 22/37 (59%)
Query: 188 QSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTP 224
Q F C + +C+SA CDG C DGSDE GC S P
Sbjct: 142 QEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDP 178
Score = 44.8 bits (101), Expect = 0.001
Identities = 16/36 (44%), Positives = 22/36 (61%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
C ++FQC +H C+ C+GV C DGSDE C+
Sbjct: 140 CLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
R C FRC+ +C+ +W CD + DC+D SDE
Sbjct: 397 RHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDE 430
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 15 FLFSESRT---CTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
FL S S+ C EF+C RC+ +CD C D SDE
Sbjct: 129 FLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDE 171
Score = 35.9 bits (79), Expect = 0.54
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 64 MVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQC 101
++C + F+CL+ C+ RCD C DGSDE C
Sbjct: 138 LMCLQEEFQCLNHR-CVSAVQRCDGVDACGDGSDEAGC 174
Score = 33.5 bits (73), Expect = 2.9
Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
C EEF C CV CD C DGSDE C+
Sbjct: 140 CLQEEFQCLNH--RCVSAVQRCDGVDACGDGSDEAGCS 175
Score = 33.5 bits (73), Expect = 2.9
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF 343
+C A CN C DG+DE C C F C C+ + VCD DC +
Sbjct: 373 ACYLPADRCNYQTFCADGADERRCRH----CQPGN-FRCRDEKCVYETWVCDGQPDCADG 427
Query: 344 EDE 346
DE
Sbjct: 428 SDE 430
Score = 32.3 bits (70), Expect = 6.6
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
Query: 183 PTCQPQSHFSC----TDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFE 236
P C P HF C T G C C+ CADG+DE C C F
Sbjct: 354 PGCPP-GHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC-------RHCQPGNFR 405
Query: 237 CNDRITCVHRAWV 249
C D CV+ WV
Sbjct: 406 CRDE-KCVYETWV 417
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/181 (30%), Positives = 75/181 (41%), Gaps = 21/181 (11%)
Query: 267 CRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTE 319
C T D C+D C G L NG +GS C + K C+ E
Sbjct: 737 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 796
Query: 320 FD----CGGGMCI----PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDT 370
C G C VCD+ D D NEC ++ C + C++T
Sbjct: 797 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI---NECLEDKSVCQRGDCINT 853
Query: 371 PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDR 428
Y C C G++L DN+TC+DI+EC PG C C+N +G+F C C G++ R
Sbjct: 854 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 913
Query: 429 T 429
T
Sbjct: 914 T 914
Score = 69.3 bits (162), Expect = 5e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYCD 377
C G CI + D CP+ F+ + C + NECE + G C + C++T ++C
Sbjct: 845 CQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCV 901
Query: 378 CEKGYKL-IDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDRTRC 431
C++G+ + D RTCEDIDEC + C C N G+F+C C+ G+ + P+D C
Sbjct: 902 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF-QAPQDGQGC 957
Score = 66.5 bits (155), Expect = 3e-10
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYC-DCE 379
CG G C+ + R RC + +EC + ++CV++P Y C C
Sbjct: 640 CGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCT 699
Query: 380 KGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ N C D+DEC +P C+ C N +G++ C CH GY R P D C+
Sbjct: 700 EGFRGW-NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCR 751
Score = 60.1 bits (139), Expect = 3e-08
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 19/143 (13%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDK-RTEFDCGGGMCI-PLSKVCDKH-VDCP 341
C G + + C D DE CT+ + +C + R E G +CI P + + +C
Sbjct: 573 CYEGYRFSEQQRKCVD-IDE--CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCI 629
Query: 342 NFEDEPR-DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPG 400
+ ++ R D CGE C G RC YCD GY++ CEDIDEC +P
Sbjct: 630 DVDECLRPDVCGEGHCVNTVGAF--RCE------YCD--SGYRMTQRGRCEDIDECLNPS 679
Query: 401 SC-SQICINEKGTFKC-ECHTGY 421
+C + C+N G+++C C G+
Sbjct: 680 TCPDEQCVNSPGSYQCVPCTEGF 702
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSCSQ-ICINE 409
NEC N C C++ P+ Y C C +GY+ + R C DIDEC CSQ C N
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F C C G+ + T C
Sbjct: 608 EGSFLCICPAGFMAS-EEGTNC 628
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/94 (39%), Positives = 47/94 (50%), Gaps = 15/94 (15%)
Query: 342 NFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP 399
+FE+ + CG N CE NG RCV GY CDC GY L TC D++EC +
Sbjct: 1289 SFEELQAEECGILNGCE--NG----RCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDEL 1342
Query: 400 GS----CSQI-CINEKGTFKCECHTGYARDPRDR 428
+ C CIN G++KC C GY P D+
Sbjct: 1343 NNRMSLCKNAKCINTDGSYKCLCLPGYV--PSDK 1374
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC-SQICINEK 410
G N+C+K C ++ +C GYK ++N C+DI+EC G C + C+N
Sbjct: 264 GFNKCQK----CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTM 319
Query: 411 GTFKCECHTGYARDP 425
G+++C C G+ DP
Sbjct: 320 GSYRCTCKIGFGPDP 334
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 367 CVDTPIGYYCDCEKG-YKLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
C++T GY C C++G Y C D+DEC DP SC C+N +G++ C C D
Sbjct: 1114 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLD 1173
Query: 425 PRDRTRC 431
++ RC
Sbjct: 1174 ASEK-RC 1179
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/181 (30%), Positives = 75/181 (41%), Gaps = 21/181 (11%)
Query: 267 CRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTE 319
C T D C+D C G L NG +GS C + K C+ E
Sbjct: 738 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 797
Query: 320 FD----CGGGMCI----PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDT 370
C G C VCD+ D D NEC ++ C + C++T
Sbjct: 798 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI---NECLEDKSVCQRGDCINT 854
Query: 371 PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDR 428
Y C C G++L DN+TC+DI+EC PG C C+N +G+F C C G++ R
Sbjct: 855 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 914
Query: 429 T 429
T
Sbjct: 915 T 915
Score = 69.3 bits (162), Expect = 5e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYCD 377
C G CI + D CP+ F+ + C + NECE + G C + C++T ++C
Sbjct: 846 CQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCV 902
Query: 378 CEKGYKL-IDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDRTRC 431
C++G+ + D RTCEDIDEC + C C N G+F+C C+ G+ + P+D C
Sbjct: 903 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF-QAPQDGQGC 958
Score = 66.5 bits (155), Expect = 3e-10
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYC-DCE 379
CG G C+ + R RC + +EC + ++CV++P Y C C
Sbjct: 641 CGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCT 700
Query: 380 KGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ N C D+DEC +P C+ C N +G++ C CH GY R P D C+
Sbjct: 701 EGFRGW-NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCR 752
Score = 60.1 bits (139), Expect = 3e-08
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 19/143 (13%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDK-RTEFDCGGGMCI-PLSKVCDKH-VDCP 341
C G + + C D DE CT+ + +C + R E G +CI P + + +C
Sbjct: 574 CYEGYRFSEQQRKCVD-IDE--CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCI 630
Query: 342 NFEDEPR-DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPG 400
+ ++ R D CGE C G RC YCD GY++ CEDIDEC +P
Sbjct: 631 DVDECLRPDVCGEGHCVNTVGAF--RCE------YCD--SGYRMTQRGRCEDIDECLNPS 680
Query: 401 SC-SQICINEKGTFKC-ECHTGY 421
+C + C+N G+++C C G+
Sbjct: 681 TCPDEQCVNSPGSYQCVPCTEGF 703
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSCSQ-ICINE 409
NEC N C C++ P+ Y C C +GY+ + R C DIDEC CSQ C N
Sbjct: 549 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 608
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F C C G+ + T C
Sbjct: 609 EGSFLCICPAGFMAS-EEGTNC 629
Score = 55.2 bits (127), Expect = 8e-07
Identities = 37/94 (39%), Positives = 47/94 (50%), Gaps = 15/94 (15%)
Query: 342 NFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP 399
+FE+ + CG N CE NG RCV GY CDC GY L TC D++EC +
Sbjct: 1290 SFEELQAEECGILNGCE--NG----RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDEL 1343
Query: 400 GS----CSQI-CINEKGTFKCECHTGYARDPRDR 428
+ C CIN G++KC C GY P D+
Sbjct: 1344 NNRMSLCKNAKCINTDGSYKCLCLPGYV--PSDK 1375
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC-SQICINEK 410
G N+C+K C ++ +C GYK ++N C+DI+EC G C + C+N
Sbjct: 264 GFNKCQK----CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTM 319
Query: 411 GTFKCECHTGYARDP 425
G+++C C G+ DP
Sbjct: 320 GSYRCTCKIGFGPDP 334
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 367 CVDTPIGYYCDCEKG-YKLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
C++T GY C C++G Y C D+DEC DP SC C+N +G++ C C D
Sbjct: 1115 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLD 1174
Query: 425 PRDRTRC 431
++ RC
Sbjct: 1175 ASEK-RC 1180
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/181 (30%), Positives = 75/181 (41%), Gaps = 21/181 (11%)
Query: 267 CRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTE 319
C T D C+D C G L NG +GS C + K C+ E
Sbjct: 737 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 796
Query: 320 FD----CGGGMCI----PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDT 370
C G C VCD+ D D NEC ++ C + C++T
Sbjct: 797 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI---NECLEDKSVCQRGDCINT 853
Query: 371 PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDR 428
Y C C G++L DN+TC+DI+EC PG C C+N +G+F C C G++ R
Sbjct: 854 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 913
Query: 429 T 429
T
Sbjct: 914 T 914
Score = 69.3 bits (162), Expect = 5e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYCD 377
C G CI + D CP+ F+ + C + NECE + G C + C++T ++C
Sbjct: 845 CQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCV 901
Query: 378 CEKGYKL-IDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDRTRC 431
C++G+ + D RTCEDIDEC + C C N G+F+C C+ G+ + P+D C
Sbjct: 902 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF-QAPQDGQGC 957
Score = 66.5 bits (155), Expect = 3e-10
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYC-DCE 379
CG G C+ + R RC + +EC + ++CV++P Y C C
Sbjct: 640 CGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCT 699
Query: 380 KGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ N C D+DEC +P C+ C N +G++ C CH GY R P D C+
Sbjct: 700 EGFRGW-NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCR 751
Score = 60.1 bits (139), Expect = 3e-08
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 19/143 (13%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDK-RTEFDCGGGMCI-PLSKVCDKH-VDCP 341
C G + + C D DE CT+ + +C + R E G +CI P + + +C
Sbjct: 573 CYEGYRFSEQQRKCVD-IDE--CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCI 629
Query: 342 NFEDEPR-DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPG 400
+ ++ R D CGE C G RC YCD GY++ CEDIDEC +P
Sbjct: 630 DVDECLRPDVCGEGHCVNTVGAF--RCE------YCD--SGYRMTQRGRCEDIDECLNPS 679
Query: 401 SC-SQICINEKGTFKC-ECHTGY 421
+C + C+N G+++C C G+
Sbjct: 680 TCPDEQCVNSPGSYQCVPCTEGF 702
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSCSQ-ICINE 409
NEC N C C++ P+ Y C C +GY+ + R C DIDEC CSQ C N
Sbjct: 548 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F C C G+ + T C
Sbjct: 608 EGSFLCICPAGFMAS-EEGTNC 628
Score = 55.2 bits (127), Expect = 8e-07
Identities = 37/94 (39%), Positives = 47/94 (50%), Gaps = 15/94 (15%)
Query: 342 NFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP 399
+FE+ + CG N CE NG RCV GY CDC GY L TC D++EC +
Sbjct: 1289 SFEELQAEECGILNGCE--NG----RCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDEL 1342
Query: 400 GS----CSQI-CINEKGTFKCECHTGYARDPRDR 428
+ C CIN G++KC C GY P D+
Sbjct: 1343 NNRMSLCKNAKCINTDGSYKCLCLPGYV--PSDK 1374
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC-SQICINEK 410
G N+C+K C ++ +C GYK ++N C+DI+EC G C + C+N
Sbjct: 264 GFNKCQK----CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTM 319
Query: 411 GTFKCECHTGYARDP 425
G+++C C G+ DP
Sbjct: 320 GSYRCTCKIGFGPDP 334
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 367 CVDTPIGYYCDCEKG-YKLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
C++T GY C C++G Y C D+DEC DP SC C+N +G++ C C D
Sbjct: 1114 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLD 1173
Query: 425 PRDRTRC 431
++ RC
Sbjct: 1174 ASEK-RC 1179
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/181 (30%), Positives = 75/181 (41%), Gaps = 21/181 (11%)
Query: 267 CRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTE 319
C T D C+D C G L NG +GS C + K C+ E
Sbjct: 191 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 250
Query: 320 FD----CGGGMCI----PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDT 370
C G C VCD+ D D NEC ++ C + C++T
Sbjct: 251 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI---NECLEDKSVCQRGDCINT 307
Query: 371 PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDR 428
Y C C G++L DN+TC+DI+EC PG C C+N +G+F C C G++ R
Sbjct: 308 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 367
Query: 429 T 429
T
Sbjct: 368 T 368
Score = 69.3 bits (162), Expect = 5e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYCD 377
C G CI + D CP+ F+ + C + NECE + G C + C++T ++C
Sbjct: 299 CQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCV 355
Query: 378 CEKGYKL-IDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDRTRC 431
C++G+ + D RTCEDIDEC + C C N G+F+C C+ G+ + P+D C
Sbjct: 356 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF-QAPQDGQGC 411
Score = 66.5 bits (155), Expect = 3e-10
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYC-DCE 379
CG G C+ + R RC + +EC + ++CV++P Y C C
Sbjct: 94 CGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCT 153
Query: 380 KGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ N C D+DEC +P C+ C N +G++ C CH GY R P D C+
Sbjct: 154 EGFRGW-NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCR 205
Score = 60.1 bits (139), Expect = 3e-08
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 19/143 (13%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDK-RTEFDCGGGMCI-PLSKVCDKH-VDCP 341
C G + + C D DE CT+ + +C + R E G +CI P + + +C
Sbjct: 27 CYEGYRFSEQQRKCVD-IDE--CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCI 83
Query: 342 NFEDEPR-DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPG 400
+ ++ R D CGE C G RC YCD GY++ CEDIDEC +P
Sbjct: 84 DVDECLRPDVCGEGHCVNTVGAF--RCE------YCD--SGYRMTQRGRCEDIDECLNPS 133
Query: 401 SC-SQICINEKGTFKC-ECHTGY 421
+C + C+N G+++C C G+
Sbjct: 134 TCPDEQCVNSPGSYQCVPCTEGF 156
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSCSQ-ICINE 409
NEC N C C++ P+ Y C C +GY+ + R C DIDEC CSQ C N
Sbjct: 2 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 61
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F C C G+ + T C
Sbjct: 62 EGSFLCICPAGFMAS-EEGTNC 82
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 367 CVDTPIGYYCDCEKG-YKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARD 424
C++T GY C C++G Y C D+DEC DP SC C+N +G++ C C D
Sbjct: 568 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLD 627
Query: 425 PRDRTRC 431
++ RC
Sbjct: 628 ASEK-RC 633
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/181 (30%), Positives = 75/181 (41%), Gaps = 21/181 (11%)
Query: 267 CRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNC------TRQKTICDKRTE 319
C T D C+D C G L NG +GS C + K C+ E
Sbjct: 691 CHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 750
Query: 320 FD----CGGGMCI----PLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQR-CVDT 370
C G C VCD+ D D NEC ++ C + C++T
Sbjct: 751 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI---NECLEDKSVCQRGDCINT 807
Query: 371 PIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDR 428
Y C C G++L DN+TC+DI+EC PG C C+N +G+F C C G++ R
Sbjct: 808 AGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 867
Query: 429 T 429
T
Sbjct: 868 T 868
Score = 69.3 bits (162), Expect = 5e-11
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 322 CGGGMCIPLSKVCDKHVDCPN-FEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYCD 377
C G CI + D CP+ F+ + C + NECE + G C + C++T ++C
Sbjct: 799 CQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCV 855
Query: 378 CEKGYKL-IDNRTCEDIDECADPGSCSQ--ICINEKGTFKCECHTGYARDPRDRTRC 431
C++G+ + D RTCEDIDEC + C C N G+F+C C+ G+ + P+D C
Sbjct: 856 CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF-QAPQDGQGC 911
Score = 66.5 bits (155), Expect = 3e-10
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query: 322 CGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYC-DCE 379
CG G C+ + R RC + +EC + ++CV++P Y C C
Sbjct: 594 CGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCT 653
Query: 380 KGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ N C D+DEC +P C+ C N +G++ C CH GY R P D C+
Sbjct: 654 EGFRGW-NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCR 705
Score = 60.1 bits (139), Expect = 3e-08
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 19/143 (13%)
Query: 285 CIPGALYCNGVKDCPDGSDEYNCTRQKTICDK-RTEFDCGGGMCI-PLSKVCDKH-VDCP 341
C G + + C D DE CT+ + +C + R E G +CI P + + +C
Sbjct: 527 CYEGYRFSEQQRKCVD-IDE--CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCI 583
Query: 342 NFEDEPR-DRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPG 400
+ ++ R D CGE C G RC YCD GY++ CEDIDEC +P
Sbjct: 584 DVDECLRPDVCGEGHCVNTVGAF--RCE------YCD--SGYRMTQRGRCEDIDECLNPS 633
Query: 401 SC-SQICINEKGTFKC-ECHTGY 421
+C + C+N G+++C C G+
Sbjct: 634 TCPDEQCVNSPGSYQCVPCTEGF 656
Score = 56.8 bits (131), Expect = 3e-07
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSCSQ-ICINE 409
NEC N C C++ P+ Y C C +GY+ + R C DIDEC CSQ C N
Sbjct: 502 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 561
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
+G+F C C G+ + T C
Sbjct: 562 EGSFLCICPAGFMAS-EEGTNC 582
Score = 55.2 bits (127), Expect = 8e-07
Identities = 37/94 (39%), Positives = 47/94 (50%), Gaps = 15/94 (15%)
Query: 342 NFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADP 399
+FE+ + CG N CE NG RCV GY CDC GY L TC D++EC +
Sbjct: 1243 SFEELQAEECGILNGCE--NG----RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDEL 1296
Query: 400 GS----CSQI-CINEKGTFKCECHTGYARDPRDR 428
+ C CIN G++KC C GY P D+
Sbjct: 1297 NNRMSLCKNAKCINTDGSYKCLCLPGYV--PSDK 1328
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 5/75 (6%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC-SQICINEK 410
G N+C+K C ++ +C GYK ++N C+DI+EC G C + C+N
Sbjct: 270 GFNKCQK----CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTM 325
Query: 411 GTFKCECHTGYARDP 425
G+++C C G+ DP
Sbjct: 326 GSYRCTCKIGFGPDP 340
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 367 CVDTPIGYYCDCEKG-YKLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
C++T GY C C++G Y C D+DEC DP SC C+N +G++ C C D
Sbjct: 1068 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLD 1127
Query: 425 PRDRTRC 431
++ RC
Sbjct: 1128 ASEK-RC 1133
>BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein.
Length = 321
Score = 75.4 bits (177), Expect = 7e-13
Identities = 34/76 (44%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 348 RDRC-GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ 404
R C ENECE+NNGGCS+ CV+ Y C+C G L D +TCED++ C + G CS
Sbjct: 177 RQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH 236
Query: 405 ICINEKGTFKCECHTG 420
C+ + ++CEC G
Sbjct: 237 SCLGSEKGYQCECPRG 252
Score = 46.8 bits (106), Expect = 3e-04
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCE 391
C NNGGCS C+ + GY C+C +G L DN TC+
Sbjct: 227 CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
Score = 32.7 bits (71), Expect = 5.0
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 6/47 (12%)
Query: 700 DGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ V C NG CSH CL + + C CP GL L D+ C
Sbjct: 222 EDVEGCHNNNGGCSHSCLGSEK------GYQCECPRGLVLSEDNHTC 262
>AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein.
Length = 545
Score = 75.4 bits (177), Expect = 7e-13
Identities = 34/76 (44%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 348 RDRC-GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ 404
R C ENECE+NNGGCS+ CV+ Y C+C G L D +TCED++ C + G CS
Sbjct: 177 RQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH 236
Query: 405 ICINEKGTFKCECHTG 420
C+ + ++CEC G
Sbjct: 237 SCLGSEKGYQCECPRG 252
Score = 46.8 bits (106), Expect = 3e-04
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCE 391
C NNGGCS C+ + GY C+C +G L DN TC+
Sbjct: 227 CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
Score = 32.7 bits (71), Expect = 5.0
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 6/47 (12%)
Query: 700 DGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ V C NG CSH CL + + C CP GL L D+ C
Sbjct: 222 EDVEGCHNNNGGCSHSCLGSEK------GYQCECPRGLVLSEDNHTC 262
>AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein.
Length = 545
Score = 75.4 bits (177), Expect = 7e-13
Identities = 34/76 (44%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 348 RDRC-GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ 404
R C ENECE+NNGGCS+ CV+ Y C+C G L D +TCED++ C + G CS
Sbjct: 177 RQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH 236
Query: 405 ICINEKGTFKCECHTG 420
C+ + ++CEC G
Sbjct: 237 SCLGSEKGYQCECPRG 252
Score = 46.8 bits (106), Expect = 3e-04
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCE 391
C NNGGCS C+ + GY C+C +G L DN TC+
Sbjct: 227 CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
Score = 32.7 bits (71), Expect = 5.0
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 6/47 (12%)
Query: 700 DGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ V C NG CSH CL + + C CP GL L D+ C
Sbjct: 222 EDVEGCHNNNGGCSHSCLGSEK------GYQCECPRGLVLSEDNHTC 262
>AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ39116 fis, clone NTONG2006301, highly similar to
Mus musculus EF-9 mRNA. ).
Length = 545
Score = 75.4 bits (177), Expect = 7e-13
Identities = 34/76 (44%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 348 RDRC-GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ 404
R C ENECE+NNGGCS+ CV+ Y C+C G L D +TCED++ C + G CS
Sbjct: 177 RQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSH 236
Query: 405 ICINEKGTFKCECHTG 420
C+ + ++CEC G
Sbjct: 237 SCLGSEKGYQCECPRG 252
Score = 46.8 bits (106), Expect = 3e-04
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCE 391
C NNGGCS C+ + GY C+C +G L DN TC+
Sbjct: 227 CHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQ 263
Score = 32.7 bits (71), Expect = 5.0
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 6/47 (12%)
Query: 700 DGVNHCAAVNGHCSHLCLPAPRFGPNSPRVSCACPNGLKLLPDDQMC 746
+ V C NG CSH CL + + C CP GL L D+ C
Sbjct: 222 EDVEGCHNNNGGCSHSCLGSEK------GYQCECPRGLVLSEDNHTC 262
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 74.9 bits (176), Expect = 9e-13
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICIN 408
C + C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN 296
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVND 464
G+F C+C++GYA D RC A + S +H+ + HE A+ D
Sbjct: 297 VPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 465 TKSATALDY 473
K+ T +DY
Sbjct: 356 KKTCTKIDY 364
Score = 72.9 bits (171), Expect = 4e-12
Identities = 52/172 (30%), Positives = 73/172 (42%), Gaps = 21/172 (12%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 276 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 335
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEK 380
S +C H F P + C + + C +N GC CV+T Y C C K
Sbjct: 336 VNA---DGSYLCQCH---EGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLK 389
Query: 381 GYKL-IDNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
G+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 390 GFTLNPDKKTCRRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 440
Score = 70.1 bits (164), Expect = 3e-11
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-SCSQICINEKG 411
N C N GC CV+ YYC C +GY L N +TC +D CA C Q+C+N +
Sbjct: 404 NYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTED 463
Query: 412 TFKCECHTGY 421
+F C+C G+
Sbjct: 464 SFVCQCSEGF 473
Score = 59.3 bits (137), Expect = 5e-08
Identities = 86/391 (21%), Positives = 135/391 (34%), Gaps = 36/391 (9%)
Query: 58 VCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVE-ACGPEEFTCRGK 116
+CTA +C C + IP S+ C SD+ C ++ C E+ C
Sbjct: 236 LCTAH--MCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 293
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXX 174
VP +++C + D K C + C S+ C + +C+
Sbjct: 294 CVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVN---ADGSYLCQCHE 348
Query: 175 XXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTE 234
+ TC + + ++ C + D C G P ++ C
Sbjct: 349 GFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLK---GFTLNPDKKT-CRRIN 404
Query: 235 FECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNG 294
+ ++ C H L+ G R+D +DH C L
Sbjct: 405 YCALNKPGCEHECVNMEESYYCRCHRGYTLDP-NGKTCSRVDHCAQQDHGCEQLCLNTED 463
Query: 295 --VKDCPDG----SDEYNCTRQK--TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
V C +G D C+R + D E+ C + + S C CP
Sbjct: 464 SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC---VNMDRSFACQ----CPEGHVL 516
Query: 347 PRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGS 401
D C + + C + GC CV + + C C +GY L D +TC D C A
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHG 576
Query: 402 CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C IC+N ++ CEC G+ R D RC+
Sbjct: 577 CEHICVNSDDSYTCECLVGF-RLAEDGKRCR 606
Score = 58.8 bits (136), Expect = 7e-08
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPG-SCSQICINEKGTF 413
C+ + GC CV++ Y C+C G++L D + C D C C IC+N ++
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSY 629
Query: 414 KCECHTGYARDPRDRTRC-KATEGHPSLLF 442
C+C G+ D RC K TEG L+F
Sbjct: 630 ICKCSEGFVL-AEDGRRCKKCTEGPIDLVF 658
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 74.9 bits (176), Expect = 9e-13
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICIN 408
C + C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN 296
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVND 464
G+F C+C++GYA D RC A + S +H+ + HE A+ D
Sbjct: 297 VPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 465 TKSATALDY 473
K+ T +DY
Sbjct: 356 EKTCTKIDY 364
Score = 73.7 bits (173), Expect = 2e-12
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 19/171 (11%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 276 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 335
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEKG 381
S +C H DE C + + C +N GC CV+T Y C C KG
Sbjct: 336 VNA---DGSYLCQCHEGFALNPDEKT--CTKIDYCASSNHGCQHECVNTDDSYSCHCLKG 390
Query: 382 YKL-IDNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 391 FTLNPDKKTCRRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 440
Score = 70.1 bits (164), Expect = 3e-11
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-SCSQICINEKG 411
N C N GC CV+ YYC C +GY L N +TC +D CA C Q+C+N +
Sbjct: 404 NYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTED 463
Query: 412 TFKCECHTGY 421
+F C+C G+
Sbjct: 464 SFVCQCSEGF 473
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPG-SCSQICINEKGTF 413
C+ + GC CV++ Y C+C +G++L D + C D C C IC+N ++
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSY 629
Query: 414 KCECHTGYARDPRDRTRC-KATEGHPSLLF 442
C+C G+ D RC K TEG L+F
Sbjct: 630 ICKCSEGFVL-AEDGRRCKKCTEGPIDLVF 658
Score = 58.8 bits (136), Expect = 7e-08
Identities = 86/391 (21%), Positives = 135/391 (34%), Gaps = 36/391 (9%)
Query: 58 VCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVE-ACGPEEFTCRGK 116
+CTA +C C + IP S+ C SD+ C ++ C E+ C
Sbjct: 236 LCTAH--MCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 293
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXX 174
VP +++C + D K C + C S+ C + +C+
Sbjct: 294 CVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVN---ADGSYLCQCHE 348
Query: 175 XXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTE 234
+ TC + + ++ C + D C G P ++ C
Sbjct: 349 GFALNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLK---GFTLNPDKKT-CRRIN 404
Query: 235 FECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNG 294
+ ++ C H L+ G R+D +DH C L
Sbjct: 405 YCALNKPGCEHECVNMEESYYCRCHRGYTLDP-NGKTCSRVDHCAQQDHGCEQLCLNTED 463
Query: 295 --VKDCPDG----SDEYNCTRQK--TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
V C +G D C+R + D E+ C + + S C CP
Sbjct: 464 SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC---VNMDRSFACQ----CPEGHVL 516
Query: 347 PRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGS 401
D C + + C + GC CV + + C C +GY L D +TC D C A
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHG 576
Query: 402 CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C IC+N ++ CEC G+ R D RC+
Sbjct: 577 CEHICVNSDDSYTCECLEGF-RLAEDGKRCR 606
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 74.9 bits (176), Expect = 9e-13
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICIN 408
C + C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N
Sbjct: 297 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN 356
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVND 464
G+F C+C++GYA D RC A + S +H+ + HE A+ D
Sbjct: 357 VPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 415
Query: 465 TKSATALDY 473
K+ T +DY
Sbjct: 416 EKTCTKIDY 424
Score = 73.7 bits (173), Expect = 2e-12
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 19/171 (11%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 336 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 395
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEKG 381
S +C H DE C + + C +N GC CV+T Y C C KG
Sbjct: 396 VNA---DGSYLCQCHEGFALNPDEKT--CTKIDYCASSNHGCQHECVNTDDSYSCHCLKG 450
Query: 382 YKL-IDNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 451 FTLNPDKKTCRRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 500
Score = 70.1 bits (164), Expect = 3e-11
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-SCSQICINEKG 411
N C N GC CV+ YYC C +GY L N +TC +D CA C Q+C+N +
Sbjct: 464 NYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTED 523
Query: 412 TFKCECHTGY 421
+F C+C G+
Sbjct: 524 SFVCQCSEGF 533
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPG-SCSQICINEKGTF 413
C+ + GC CV++ Y C+C +G++L D + C D C C IC+N ++
Sbjct: 630 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSY 689
Query: 414 KCECHTGYARDPRDRTRC-KATEGHPSLLF 442
C+C G+ D RC K TEG L+F
Sbjct: 690 ICKCSEGFVL-AEDGRRCKKCTEGPIDLVF 718
Score = 58.8 bits (136), Expect = 7e-08
Identities = 86/391 (21%), Positives = 135/391 (34%), Gaps = 36/391 (9%)
Query: 58 VCTATKMVCQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVE-ACGPEEFTCRGK 116
+CTA +C C + IP S+ C SD+ C ++ C E+ C
Sbjct: 296 LCTAH--MCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 353
Query: 117 PGECVPLTWMCDDNPDCSDGSDEKACN--ETCRSDEFTCGNGKCIQMRWVXXXXXXXXXX 174
VP +++C + D K C + C S+ C + +C+
Sbjct: 354 CVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVN---ADGSYLCQCHE 408
Query: 175 XXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTE 234
+ TC + + ++ C + D C G P ++ C
Sbjct: 409 GFALNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLK---GFTLNPDKKT-CRRIN 464
Query: 235 FECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNG 294
+ ++ C H L+ G R+D +DH C L
Sbjct: 465 YCALNKPGCEHECVNMEESYYCRCHRGYTLDP-NGKTCSRVDHCAQQDHGCEQLCLNTED 523
Query: 295 --VKDCPDG----SDEYNCTRQK--TICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDE 346
V C +G D C+R + D E+ C + + S C CP
Sbjct: 524 SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC---VNMDRSFACQ----CPEGHVL 576
Query: 347 PRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGS 401
D C + + C + GC CV + + C C +GY L D +TC D C A
Sbjct: 577 RSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHG 636
Query: 402 CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C IC+N ++ CEC G+ R D RC+
Sbjct: 637 CEHICVNSDDSYTCECLEGF-RLAEDGKRCR 666
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 74.9 bits (176), Expect = 9e-13
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICIN 408
C + C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N
Sbjct: 237 CTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN 296
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVND 464
G+F C+C++GYA D RC A + S +H+ + HE A+ D
Sbjct: 297 VPGSFVCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPD 355
Query: 465 TKSATALDY 473
K+ T +DY
Sbjct: 356 KKTCTKIDY 364
Score = 72.9 bits (171), Expect = 4e-12
Identities = 52/172 (30%), Positives = 73/172 (42%), Gaps = 21/172 (12%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 276 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 335
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEP-RDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEK 380
S +C H F P + C + + C +N GC CV+T Y C C K
Sbjct: 336 VNA---DGSYLCQCH---EGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLK 389
Query: 381 GYKL-IDNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
G+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 390 GFTLNPDKKTCRRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 440
Score = 41.5 bits (93), Expect = 0.011
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTC 390
N C N GC CV+ YYC C +GY L N +TC
Sbjct: 404 NYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTC 441
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 118 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 177
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 178 ELS-SDRLNCE 187
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 126 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 181
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 182 D--RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 239
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 240 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 273
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 343 FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP 399
+E + C + +EC C Q C++ + C C GY+ + C DIDEC P
Sbjct: 57 YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP 115
Query: 400 GSCSQICINEKGTFKCECHTGY 421
C Q C+N G+F C+C G+
Sbjct: 116 PYCHQRCVNTPGSFYCQCSPGF 137
Score = 52.8 bits (121), Expect = 4e-06
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 347 PRDRCGENECE-KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSC-- 402
P + G N + N QR P + C GY+ ++ C+DIDEC A +C
Sbjct: 22 PEMQTGRNNFVIRRNPADPQRIPSNP-SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRA 80
Query: 403 SQICINEKGTFKCECHTGYAR 423
Q+CIN +G+F C+C GY +
Sbjct: 81 DQVCINLRGSFACQCPPGYQK 101
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 283
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 284 ELS-SDRLNCE 293
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 232 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 287
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 288 D--RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 379
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 343 FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP 399
+E + C + +EC C Q C++ + C C GY+ + C DIDEC P
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP 221
Query: 400 GSCSQICINEKGTFKCECHTGY 421
C Q C+N G+F C+C G+
Sbjct: 222 PYCHQRCVNTPGSFYCQCSPGF 243
Score = 52.8 bits (121), Expect = 4e-06
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 347 PRDRCGENECE-KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSC-- 402
P + G N + N QR P + C GY+ ++ C+DIDEC A +C
Sbjct: 128 PEMQTGRNNFVIRRNPADPQRIPSNP-SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRA 186
Query: 403 SQICINEKGTFKCECHTGYAR 423
Q+CIN +G+F C+C GY +
Sbjct: 187 DQVCINLRGSFACQCPPGYQK 207
>BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein.
Length = 219
Score = 74.5 bits (175), Expect = 1e-12
Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 13/156 (8%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-TEFDCGGGMC 327
G+ T L F C CI V C DG C C + + C G C
Sbjct: 64 GHCTLPLCSFGCGSGICI-----APNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGC 118
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-I 385
+++VC V E RC + +EC ++ C CV+T G+ C+C G +L
Sbjct: 119 QEVARVCP--VGFSMTETAVGIRCTDIDECVTSS--CEGHCVNTEGGFVCECGPGMQLSA 174
Query: 386 DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
D +C+D DEC C Q C N G++KC C TG+
Sbjct: 175 DRHSCQDTDECLGT-PCQQRCKNSIGSYKCSCRTGF 209
>BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein.
Length = 219
Score = 74.5 bits (175), Expect = 1e-12
Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 13/156 (8%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-TEFDCGGGMC 327
G+ T L F C CI V C DG C C + + C G C
Sbjct: 64 GHCTLPLCSFGCGSGICI-----APNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGC 118
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-I 385
+++VC V E RC + +EC ++ C CV+T G+ C+C G +L
Sbjct: 119 QEVARVCP--VGFSMTETAVGIRCTDIDECVTSS--CEGHCVNTEGGFVCECGPGMQLSA 174
Query: 386 DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
D +C+D DEC C Q C N G++KC C TG+
Sbjct: 175 DRHSCQDTDECLGT-PCQQRCKNSIGSYKCSCRTGF 209
>BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein.
Length = 237
Score = 74.5 bits (175), Expect = 1e-12
Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 13/156 (8%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-TEFDCGGGMC 327
G+ T L F C CI V C DG C C + + C G C
Sbjct: 82 GHCTLPLCSFGCGSGICI-----APNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGC 136
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-I 385
+++VC V E RC + +EC ++ C CV+T G+ C+C G +L
Sbjct: 137 QEVARVCP--VGFSMTETAVGIRCTDIDECVTSS--CEGHCVNTEGGFVCECGPGMQLSA 192
Query: 386 DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
D +C+D DEC C Q C N G++KC C TG+
Sbjct: 193 DRHSCQDTDECLGT-PCQQRCKNSIGSYKCSCRTGF 227
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 283
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 284 ELS-SDRLNCE 293
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 232 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 287
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 288 D--RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 379
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 343 FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP 399
+E + C + +EC C Q C++ + C C GY+ + C DIDEC P
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP 221
Query: 400 GSCSQICINEKGTFKCECHTGY 421
C Q C+N G+F C+C G+
Sbjct: 222 PYCHQRCVNTPGSFYCQCSPGF 243
Score = 52.8 bits (121), Expect = 4e-06
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 347 PRDRCGENECE-KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSC-- 402
P + G N + N QR P + C GY+ ++ C+DIDEC A +C
Sbjct: 128 PEMQTGRNNFVIRRNPADPQRIPSNP-SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRA 186
Query: 403 SQICINEKGTFKCECHTGYAR 423
Q+CIN +G+F C+C GY +
Sbjct: 187 DQVCINLRGSFACQCPPGYQK 207
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 224 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 283
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 284 ELS-SDRLNCE 293
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 232 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 287
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 288 D--RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 345
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 346 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 379
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 343 FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP 399
+E + C + +EC C Q C++ + C C GY+ + C DIDEC P
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP 221
Query: 400 GSCSQICINEKGTFKCECHTGY 421
C Q C+N G+F C+C G+
Sbjct: 222 PYCHQRCVNTPGSFYCQCSPGF 243
Score = 52.8 bits (121), Expect = 4e-06
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 347 PRDRCGENECE-KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSC-- 402
P + G N + N QR P + C GY+ ++ C+DIDEC A +C
Sbjct: 128 PEMQTGRNNFVIRRNPADPQRIPSNP-SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRA 186
Query: 403 SQICINEKGTFKCECHTGYAR 423
Q+CIN +G+F C+C GY +
Sbjct: 187 DQVCINLRGSFACQCPPGYQK 207
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 51 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 110
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 111 ELS-SDRLNCE 120
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 59 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 114
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 115 D--RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 172
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 173 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 206
Score = 56.8 bits (131), Expect = 3e-07
Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 354 NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKG 411
+EC C Q C++ + C C GY+ + C DIDEC P C Q C+N G
Sbjct: 2 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIPPYCHQRCVNTPG 60
Query: 412 TFKCECHTGY 421
+F C+C G+
Sbjct: 61 SFYCQCSPGF 70
Score = 35.9 bits (79), Expect = 0.54
Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
Query: 393 IDEC-ADPGSC--SQICINEKGTFKCECHTGYAR 423
IDEC A +C Q+CIN +G+F C+C GY +
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQK 34
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 74.5 bits (175), Expect = 1e-12
Identities = 32/71 (45%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C QRCV+TP +YC C G++L +N TC DI+EC C+Q C N G+F C+C+ GY
Sbjct: 149 CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGY 208
Query: 422 ARDPRDRTRCK 432
DR C+
Sbjct: 209 ELS-SDRLNCE 218
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--SKVCDKHVDCPNFE 344
PG+ YC ++ Y C CD + C C + S +C +
Sbjct: 157 PGSFYCQCSPGFQLAANNYTCVDINE-CDASNQ--CAQ-QCYNILGSFICQCNQGYELSS 212
Query: 345 DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC- 402
D R C + +EC ++ C +CV+ P + C C +GY+++ +RTC+DI+EC C
Sbjct: 213 D--RLNCEDIDECRTSSYLCQYQCVNQPGKFSCMCPQGYQVVRSRTCQDINECETTNECR 270
Query: 403 -SQICINEKGTFKC----ECHTGYARDPRDRTRC 431
++C N G F+C C Y P +R C
Sbjct: 271 EDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVC 304
Score = 58.0 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 343 FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP 399
+E + C + +EC C Q C++ + C C GY+ + C DIDEC P
Sbjct: 88 YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ-CVDIDECTIP 146
Query: 400 GSCSQICINEKGTFKCECHTGY 421
C Q C+N G+F C+C G+
Sbjct: 147 PYCHQRCVNTPGSFYCQCSPGF 168
Score = 52.8 bits (121), Expect = 4e-06
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 347 PRDRCGENECE-KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSC-- 402
P + G N + N QR P + C GY+ ++ C+DIDEC A +C
Sbjct: 53 PEMQTGRNNFVIRRNPADPQRIPSNP-SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRA 111
Query: 403 SQICINEKGTFKCECHTGYAR 423
Q+CIN +G+F C+C GY +
Sbjct: 112 DQVCINLRGSFACQCPPGYQK 132
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 74.5 bits (175), Expect = 1e-12
Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Query: 270 NVT--CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC 327
NVT C+L ++ C++ CIP C +C G + + + D+ + C GG C
Sbjct: 448 NVTDYCQLVRYLCQNGRCIPTPGSCRC--ECNKGF-QLDLRGECIDVDECEKNPCAGGEC 504
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI 385
I R C + +EC +N C+ RC++T ++C C G+ +
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGY 421
D + CED+DEC+ C + +CINE G+FKC C G+
Sbjct: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
Score = 69.3 bits (162), Expect = 5e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 20/161 (12%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMC 327
C+ D C+ C G+ C +CP G S + C+ C G C
Sbjct: 1117 CQRDPLLCRGGVCHNTEGSYRC----ECPPGHQLSPNISACIDINECELSAHL-CPNGRC 1171
Query: 328 IPLSKVCDKHVDC-PNFEDEPRDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ L + C P + P DR C + +EC NGGC C ++ Y C C+ G+
Sbjct: 1172 VNL--IGKYQCACNPGYHSTP-DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFA 1228
Query: 384 LI-DNRTCEDIDECAD-PGSC-SQICINEKGTFKCECHTGY 421
L+ D R+C DIDEC D P C C N G ++C C+ G+
Sbjct: 1229 LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
Score = 64.5 bits (150), Expect = 1e-09
Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICD----KRTEFDCGGGM 326
CR+ C C+ PG C C +G E K D +R C GG+
Sbjct: 1074 CRISPDLCGRGQCVNTPGDFECK----CDEGY-ESGFMMMKNCMDIDECQRDPLLCRGGV 1128
Query: 327 CIPLSKVCDKHVDCP-NFEDEPR-DRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
C +CP + P C + NECE + C RCV+ Y C C GY
Sbjct: 1129 CHNTEG--SYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Query: 383 KLIDNRT-CEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
+R C DIDEC+ G C C N +G+++C C G+A P R+
Sbjct: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
Score = 62.9 bits (146), Expect = 4e-09
Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKG 411
NEC N+ C +C +TP + C C KG+ D +TCEDIDEC + +C N G
Sbjct: 767 NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPG 826
Query: 412 TFKCECHTGYARDPRDRTRCKAT 434
+F CEC + DP +T C T
Sbjct: 827 SFICECSSESTLDP-TKTICIET 848
Score = 61.7 bits (143), Expect = 9e-09
Identities = 47/159 (29%), Positives = 69/159 (43%), Gaps = 14/159 (8%)
Query: 275 LDQFQCKDHSCIPGALYCN-GVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGGMCI 328
+D +C+ + C G N G C + Y T +T C E C G CI
Sbjct: 489 IDVDECEKNPCAGGECINNQGSYTCQCRAG-YQSTLTRTECRDIDECLQNGRICNNGRCI 547
Query: 329 PLSKVCDKHVDCPNFEDEPRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
H C RD C + +EC N + C++ + C C+ G++L
Sbjct: 548 NTDG--SFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLA 605
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYA 422
D R C+DI+EC PG C + C+N G+++CEC G A
Sbjct: 606 SDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLA 644
Score = 60.9 bits (141), Expect = 2e-08
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGYARDP 425
RC+ TP C+C KG++L C D+DEC CIN +G++ C+C GY +
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGY-QST 522
Query: 426 RDRTRCK 432
RT C+
Sbjct: 523 LTRTECR 529
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECAD-PGSC-SQICINE 409
+EC+ G C C++T + C C G+KL + ++ CEDIDEC+ PG C C N
Sbjct: 248 DECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNT 307
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
++ C+C G+ P D TRC
Sbjct: 308 VSSYFCKCPPGFYTSP-DGTRC 328
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C KGY I CEDIDEC PG C +C+N +G+FKC+C +G D R
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 948
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/148 (32%), Positives = 62/148 (41%), Gaps = 19/148 (12%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMC--IPLSKVCDKHVDCP 341
SC PG + C D DE C ICD GG C IP C +
Sbjct: 1222 SCQPGFALMPDQRSCTD-IDE--CEDNPNICD--------GGQCTNIPGEYRCLCYDGFM 1270
Query: 342 NFEDEPRDRCGENECEKNNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECA-D 398
ED + NEC+ N C S C +T + C C+ GY +T C DI+EC
Sbjct: 1271 ASEDM-KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
Query: 399 PGSCSQ--ICINEKGTFKCECHTGYARD 424
+C + +C N G+FKC C G+ D
Sbjct: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIGD 1357
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ-ICINE 409
NEC+ C+ +C +T + C C+ G+ L + R C DIDEC P C + C+N
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 410 KGTFKCECHTGY 421
G F+C+C GY
Sbjct: 1090 PGDFECKCDEGY 1101
Score = 43.6 bits (98), Expect = 0.003
Identities = 78/335 (23%), Positives = 116/335 (34%), Gaps = 46/335 (13%)
Query: 106 CGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSD---EKACNETCRSDEFTCGNGKCI--Q 160
C + C+ G C+P C +C+ G C + ++ C G+CI Q
Sbjct: 453 CQLVRYLCQN--GRCIPTPGSC--RCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQ 508
Query: 161 MRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
+ +C Q+ C +G+CI+ DG C + G
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT----DGSFHCVCNA---GF 561
Query: 221 VSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQC 280
T ++ C + EC+ R C++ + +C+ D C
Sbjct: 562 HVTRDGKN-CEDMD-ECSIRNMCLNGMCINEDGSFKC--------ICKPGFQLASDGRYC 611
Query: 281 KD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP--LSKVCD-- 335
KD + C + NG DGS Y C C G +C+ + C
Sbjct: 612 KDINECETPGICMNGRCVNTDGS--YRCE-----CFPGLAVGLDGRVCVDTHMRSTCYGG 664
Query: 336 -KHVDC--PNFEDEPRDRCGENECEKNNGGCSQRC-VDTPIGYYCDCEKGYKLIDNRTCE 391
K C P F + C E G Q C Y C G + +
Sbjct: 665 YKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS-- 722
Query: 392 DIDECA-DPGSCSQ-ICINEKGTFKCECHTGYARD 424
DI+ECA DP C IC N +GT+KC C++GY D
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVD 757
Score = 41.9 bits (94), Expect = 0.008
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C CIN G+F+C+C G+
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGH 277
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC P C+ C N G+FKC C +G+A D +R
Sbjct: 1027 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1066
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 18/160 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMC 327
C + C+ +C+ G+ C DCP G E + +R+ + C G C
Sbjct: 410 CERNPLLCRGGTCVNTEGSFQC----DCPLGH-ELSPSREDCVDINECSLSDNLCRNGKC 464
Query: 328 IPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
+ + + C P ++ P R C + +EC NGGC +C ++ Y C C +GY L
Sbjct: 465 VNM--IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 522
Query: 385 I-DNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
+ D R+C DIDEC +P C C N G ++C C+ G+
Sbjct: 523 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF 562
Score = 73.3 bits (172), Expect = 3e-12
Identities = 51/165 (30%), Positives = 70/165 (42%), Gaps = 11/165 (6%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
CR+ C C+ PG+ C + G C+ R C GG C+
Sbjct: 367 CRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCE-RNPLLCRGGTCVNT 425
Query: 331 SKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI- 385
DCP E P R+ C + NEC ++ C +CV+ Y C C GY+
Sbjct: 426 EG--SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 483
Query: 386 DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
D + C DIDEC G C C N +G+++C C GYA P R+
Sbjct: 484 DRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRS 528
Score = 72.1 bits (169), Expect = 7e-12
Identities = 91/393 (23%), Positives = 137/393 (34%), Gaps = 48/393 (12%)
Query: 77 GLCI--PRSWRCDATADCPDG--SDEHQCEVEACGPEEFTCRGKPGECVPL--TWMCDD- 129
G+C+ P S+ C+ G ++ +++ C CRG G CV ++ CD
Sbjct: 377 GICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRG--GTCVNTEGSFQCDCP 434
Query: 130 -NPDCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQ 188
+ S ++ C + C NGKC+ M + C
Sbjct: 435 LGHELSPSREDCVDINECSLSDNLCRNGKCVNM-----------IGTYQCSCNPGYQATP 483
Query: 189 SHFSCTD-GQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRA 247
CTD +C+ CD ++GS E C + S C D C +
Sbjct: 484 DRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRS----CADIDECENNP 539
Query: 248 WVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKD-HSCIPGALYCNGVKDCPDGSDEYN 306
+ E LC +D C D + C + C +C + +
Sbjct: 540 DICDGGQCTNIPG-EYRCLCYDGFMASMDMKTCIDVNECDLNSNICM-FGECENTKGSFI 597
Query: 307 CTRQKTICDKRTEFDCGG-GMCIPLSKVCDKHVDCPNFEDEPRDRCGE------------ 353
C Q K+ C C + CD H C N + C E
Sbjct: 598 CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDR 657
Query: 354 NECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADP-GSCSQ-ICINE 409
+EC CS +CV+TP Y C C +G+ D TC D+DECA+ C C+N
Sbjct: 658 DECSNGTHQCSINAQCVNTPGSYRCACSEGFTG-DGFTCSDVDECAENINLCENGQCLNV 716
Query: 410 KGTFKCECHTGYARDPRDRTRCKATEGHPSLLF 442
G ++CEC G+ D C+ L+F
Sbjct: 717 PGAYRCECEMGFT-PASDSRSCQGGSPGFQLIF 748
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSC-SQICINE 409
NEC+ G C+ +C +T + C C G+ L ++ R C DIDEC P C S IC+N
Sbjct: 323 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNT 382
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 383 PGSFECECFEGY 394
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKG 411
+EC N C C +TP Y C C GY + TCEDI+EC + C N G
Sbjct: 60 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLG 119
Query: 412 TFKCECHTG 420
+F CEC G
Sbjct: 120 SFNCECSPG 128
Score = 52.0 bits (119), Expect = 8e-06
Identities = 47/165 (28%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 272 TCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIP-L 330
TC D +C+ + C+ GA C + +NC C ++ G +CI L
Sbjct: 97 TCE-DINECESNPCVNGA--------CRNNLGSFNCE-----CSPGSKLSSTGLICIDSL 142
Query: 331 SKVCDKHVDCPNFEDEPRDRCGENECEKNNGGC----SQRC-VDTPIGYYCDCEKGYKLI 385
C ++ E ++EC G +RC +DT C +G I
Sbjct: 143 KGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTA------CPRGLARI 196
Query: 386 DNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
TCED++EC PG C C+N KG+F CEC G D R
Sbjct: 197 KGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGR 241
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ-ICINE 409
NEC + C+ C + Y C+C GY+ R C DIDEC + C +C N
Sbjct: 18 NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT 77
Query: 410 KGTFKCECHTGY 421
G++ C C GY
Sbjct: 78 PGSYSCTCPPGY 89
Score = 41.9 bits (94), Expect = 0.008
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 6/54 (11%)
Query: 378 CEKGYKL-IDNRTCEDIDECA-DPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C G + +D R DI+ECA DP C+ IC N +G+++C C++GY D R
Sbjct: 4 CSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGR 54
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC A PG C+ C N G+FKC C++G+A D +R
Sbjct: 320 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 359
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 18/160 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMC 327
C + C+ +C+ G+ C DCP G E + +R+ + C G C
Sbjct: 1161 CERNPLLCRGGTCVNTEGSFQC----DCPLGH-ELSPSREDCVDINECSLSDNLCRNGKC 1215
Query: 328 IPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
+ + + C P ++ P R C + +EC NGGC +C ++ Y C C +GY L
Sbjct: 1216 VNM--IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 1273
Query: 385 I-DNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
+ D R+C DIDEC +P C C N G ++C C+ G+
Sbjct: 1274 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF 1313
Score = 73.3 bits (172), Expect = 3e-12
Identities = 51/165 (30%), Positives = 70/165 (42%), Gaps = 11/165 (6%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
CR+ C C+ PG+ C + G C+ R C GG C+
Sbjct: 1118 CRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCE-RNPLLCRGGTCVNT 1176
Query: 331 SKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI- 385
DCP E P R+ C + NEC ++ C +CV+ Y C C GY+
Sbjct: 1177 EG--SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 1234
Query: 386 DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
D + C DIDEC G C C N +G+++C C GYA P R+
Sbjct: 1235 DRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRS 1279
Score = 71.3 bits (167), Expect = 1e-11
Identities = 53/156 (33%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 280 CKDHSCI--PGALYCNGVKDCPDGSD-EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C + CI G+ C +CP G + +Y R + CG G C + +
Sbjct: 2181 CSNGQCINTDGSFRC----ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNV--IGSF 2234
Query: 337 HVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDI 393
+C FE P C + NEC +N C+ RC++T Y C C GY L D + C+D+
Sbjct: 2235 ECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDL 2294
Query: 394 DECA----DPGSCSQICINEKGTFKCECHTGYARDP 425
DECA D S +C N GTF C C G AR P
Sbjct: 2295 DECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRP 2330
Score = 70.5 bits (165), Expect = 2e-11
Identities = 39/122 (31%), Positives = 67/122 (54%), Gaps = 20/122 (16%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFED-----EPRDRC--GENECEKNNGGCSQRCVDTP 371
C G+CI +++ +CP ++ D E D C G+N C++N C+++P
Sbjct: 1818 CANGVCI--NQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD-----CINSP 1870
Query: 372 IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
Y C+C G+KL N C D +EC + P CS +C++ +G+++C CH G+ + +D+T
Sbjct: 1871 GSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF-KASQDQT 1929
Query: 430 RC 431
C
Sbjct: 1930 MC 1931
Score = 68.5 bits (160), Expect = 8e-11
Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 315 DKRTEFDCGGGMCI--PLSKVCDKHVDCPNFEDEP-RDRCGE-NECEKNNGGCSQ-RCVD 369
D+ T C G C+ P S C H F+ P + C + +EC +N C RCV+
Sbjct: 536 DECTSNPCTNGDCVNTPGSYYCKCHA---GFQRTPTKQACIDIDECIQNGVLCKNGRCVN 592
Query: 370 TPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDPRD 427
+ + C C G++L D + C D DEC C + +CINE G+FKC C G+ P
Sbjct: 593 SDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNG 652
Query: 428 R 428
R
Sbjct: 653 R 653
Score = 64.9 bits (151), Expect = 1e-09
Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 356 CEKNNGGC-SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQICINEKGTFK 414
C+ + C + RC+ T Y C+C GYK N C D+DEC + C+N G++
Sbjct: 497 CKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYY 556
Query: 415 CECHTGYARDP 425
C+CH G+ R P
Sbjct: 557 CKCHAGFQRTP 567
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSC-SQICINE 409
NEC+ G C+ +C +T + C C G+ L ++ R C DIDEC P C S IC+N
Sbjct: 1074 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNT 1133
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 1134 PGSFECECFEGY 1145
Score = 62.9 bits (146), Expect = 4e-09
Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQICINEKG 411
+EC ++ C+ C +T Y C C +GY L D +TC+D+DEC +C +C+N G
Sbjct: 2492 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLG 2551
Query: 412 TFKCECHTGYAR 423
F C+C G+ +
Sbjct: 2552 GFTCKCPPGFTQ 2563
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 298 CPDGSDEYNC-TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC 356
C S N T+ + CD + +C PL CP+ D +EC
Sbjct: 2394 CQMASSSRNLVTKSECCCDGGRGWGHQCELC-PLPGTAQYKKICPHGPGYTTDGRDIDEC 2452
Query: 357 EKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTF 413
+ C+ +C++T + C C+ GY I +C D+DEC+ P C+ IC N +G++
Sbjct: 2453 KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSY 2512
Query: 414 KCECHTGYARDPRDRTRCK 432
+C C GY +T CK
Sbjct: 2513 QCSCPRGYVLQEDGKT-CK 2530
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/162 (28%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 273 CRLDQFQCKDHS-CI--PGALYCNGVKDCPDG--SDEYNCTRQKTICDKRTEFDCGGGMC 327
C QC ++ C+ PG+ C C +G D + C+ C + C G C
Sbjct: 1411 CSNGTHQCSINAQCVNTPGSYRCA----CSEGFTGDGFTCSDVDE-CAENINL-CENGQC 1464
Query: 328 --IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
+P + C+ + D R +EC N S C + P ++C C+ GY+L
Sbjct: 1465 LNVPGAYRCECEMGFTPASDS-RSCQDIDECSFQNICVSGTCNNLPGMFHCICDDGYELD 1523
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
C DIDECADP +C + +C+N G ++C C + +P
Sbjct: 1524 RTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNP 1565
Score = 60.9 bits (141), Expect = 2e-08
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSCSQ-ICINEKG 411
+EC N + C++ + C C+ G+ L N R C D+DEC PG C CIN +G
Sbjct: 618 DECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEG 677
Query: 412 TFKCECHTGYA 422
+F+C+C G A
Sbjct: 678 SFRCDCPPGLA 688
Score = 60.9 bits (141), Expect = 2e-08
Identities = 86/375 (22%), Positives = 136/375 (36%), Gaps = 55/375 (14%)
Query: 86 CDATADCPDGSDEHQCEVEACG---PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
C +C G+ H C++ A P F C + G + C D +CS+G+ + +
Sbjct: 1364 CTDVDECEIGA--HNCDMHASCLNIPGSFKCSCREG-WIGNGIKCIDLDECSNGTHQCSI 1420
Query: 143 NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISA- 201
N C + T G+ +C +V C + C +GQC++
Sbjct: 1421 NAQCVN---TPGSYRCA----CSEGFTGDGFTCSDVD----ECAENINL-CENGQCLNVP 1468
Query: 202 -WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXX 260
+ C+ ++ SD C + I CN+ H
Sbjct: 1469 GAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCNNLPGMFHCICDDGYELDRTGGN 1528
Query: 261 XEALELCRGNVTC-------RLDQFQCK---DHSCIPGALYC--NGVKDC-----PDGSD 303
++ C + C +++C D P + C N V +C P G
Sbjct: 1529 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 1588
Query: 304 EYNCTRQKTICDKRTEFDCGGGM--------CIPLSKVCDKHVDCPN---FEDEPRDRCG 352
+C + + R+ C G C P++ + + CP F P
Sbjct: 1589 SLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNST-EYYTLCPGGEGFRPNPITIIL 1647
Query: 353 EN--ECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-IC 406
E+ EC++ G C C++T + C+C +GY L D R CEDIDEC A PG C C
Sbjct: 1648 EDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTC 1707
Query: 407 INEKGTFKCECHTGY 421
N G + C C Y
Sbjct: 1708 YNTLGNYTCICPPEY 1722
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 23/171 (13%)
Query: 280 CKD-HSCIPGALYCNGVKDCPDGSDEYNCT-------RQKTICDKRTEF-----DCGGGM 326
C+D C G C DC + Y C C R E C G+
Sbjct: 1847 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL 1906
Query: 327 CIPL--SKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
C+ L S C H +D+ C + +ECE++ G + C +T Y C C G++
Sbjct: 1907 CVDLQGSYQCICHNGFKASQDQTM--CMDVDECERHPCG-NGTCKNTVGSYNCLCYPGFE 1963
Query: 384 LIDNRTCEDIDECAD--PGSC-SQICINEKGTFKCECHTGYARDPRDRTRC 431
L N C DIDEC+ C + C NE G+FKC C+ GY P D C
Sbjct: 1964 LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP-DGKNC 2013
Score = 59.7 bits (138), Expect = 4e-08
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 16/164 (9%)
Query: 272 TCR-LDQFQCKDHSCIPGALYCNG--VKDCPDG-SDEYNCTRQKTICDKRTEFDCGG-GM 326
TC+ LD+ Q K H+C + G CP G + + C + CGG G+
Sbjct: 2528 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLL-CGGKGI 2586
Query: 327 C--IPLSKVCDKHVDCPNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
C P S C+ F D C + +EC+ N+ C C + GY C C +GY
Sbjct: 2587 CQNTPGSFSCECQ---RGFSLDATGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGY 2642
Query: 383 -KLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
+ C D +EC++P +C S C N G++KC C +G++ D
Sbjct: 2643 IQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD 2686
Score = 59.3 bits (137), Expect = 5e-08
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 12/127 (9%)
Query: 305 YNCTRQKTIC---DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKN 359
+ ++ +T+C D+ CG G C + V + C P FE + C + +EC
Sbjct: 1922 FKASQDQTMCMDVDECERHPCGNGTC--KNTVGSYNCLCYPGFELTHNNDCLDIDECSSF 1979
Query: 360 NGGCSQ--RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINEKGTFK 414
G + RC + + C C +GY+L D + C D +EC A PGSCS C N +G+F+
Sbjct: 1980 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 2039
Query: 415 CECHTGY 421
C C GY
Sbjct: 2040 CICPPGY 2046
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 322 CGGGMCIPLSKVCDKHVDCP-NFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDC 378
C G CI +CP + D RC + +EC N + C + + C+C
Sbjct: 2181 CSNGQCINTDG--SFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNC 2238
Query: 379 EKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ CEDI+ECA +P C+ C+N G+++C C GYA D+ CK
Sbjct: 2239 NEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYAL-REDQKMCK 2292
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 354 NECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKG 411
+EC N C C +TP Y C C GY + TCEDI+EC + C N G
Sbjct: 811 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLG 870
Query: 412 TFKCECHTG 420
+F CEC G
Sbjct: 871 SFNCECSPG 879
Score = 52.8 bits (121), Expect = 4e-06
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECAD-PGSCSQ-ICINE 409
+EC+ G C C++T + C C G+K + + CEDIDEC+ PG C C N
Sbjct: 277 DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNT 336
Query: 410 KGTFKCECHTGYARDPRDRTRC 431
G++ C C GY D +RC
Sbjct: 337 VGSYFCVCPRGYVTS-TDGSRC 357
Score = 52.8 bits (121), Expect = 4e-06
Identities = 110/447 (24%), Positives = 155/447 (34%), Gaps = 73/447 (16%)
Query: 23 CTSSEFRCKTGRCIPL--SWKCDNEKDCSDSSDE----DPTVCTATKMVCQEYRFECLSD 76
C + CK GRC+ S++C ++D D CT T M CL+
Sbjct: 578 CIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNM--------CLN- 628
Query: 77 GLCIPR--SWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL--TWMCDDNP 131
G+CI S++C + C +V+ C C G C+ ++ CD P
Sbjct: 629 GMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGI-CMN--GHCINSEGSFRCDCPP 685
Query: 132 DCSDGSDEKACNETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPT------C 185
+ G D + C +T TC G + V E C P C
Sbjct: 686 GLAVGMDGRVCVDTHMRS--TCYGGI---KKGVCVRPFPGAVTKSECCCANPDYGFGEPC 740
Query: 186 QPQSHFSCTDGQCISAWWHCDGDVDCA-DGSDEVGCVSTPKVRSPCISTEFECNDRITCV 244
QP C C V DG D C P + + I + R C
Sbjct: 741 QP-----CPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNC- 794
Query: 245 HRAWVXXXXXXXXXXXXEAL--ELCRGNVTCRLD--QFQCKDHSCIPGALYCNGVKDCPD 300
+ + E L L N CR + C +C PG ++ + C D
Sbjct: 795 NSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSC---TCPPGYVFRTETETCED 851
Query: 301 GSD-EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGEN----E 355
++ E N + F+C C P SK+ + C D + C N
Sbjct: 852 INECESNPCVNGACRNNLGSFNCE---CSPGSKLSSTGLICI---DSLKGTCWLNIQDSR 905
Query: 356 CEKNNGGCSQR--CVDT---PIGYYCD-------CEKGYKLIDNRTCEDIDEC-ADPGSC 402
CE N G + + C T G C+ C +G I TCED++EC PG C
Sbjct: 906 CEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVC 965
Query: 403 SQ-ICINEKGTFKCECHTGYARDPRDR 428
C+N KG+F CEC G D R
Sbjct: 966 PNGRCVNSKGSFHCECPEGLTLDGTGR 992
Score = 52.4 bits (120), Expect = 6e-06
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Query: 354 NECEKNNGGCS-QRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECA-DPGSCSQ--ICIN 408
NEC+ N+ C C +T + C C+ GY + T C D+DEC +C C+N
Sbjct: 1326 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1385
Query: 409 EKGTFKCECHTGY 421
G+FKC C G+
Sbjct: 1386 IPGSFKCSCREGW 1398
Score = 52.4 bits (120), Expect = 6e-06
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 353 ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLID-NRTCEDIDECADPGS-CSQICINEK 410
ENEC N S C +T Y C C G+ + C D++EC+ + C+ C N +
Sbjct: 2654 ENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTE 2713
Query: 411 GTFKCECHTGYAR 423
G + C C GY R
Sbjct: 2714 GGYLCGCPPGYYR 2726
Score = 51.2 bits (117), Expect = 1e-05
Identities = 45/161 (27%), Positives = 64/161 (39%), Gaps = 18/161 (11%)
Query: 273 CRLDQFQCKDHSCIP--GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L C++ C+ G C+ C G Y T + C E G C
Sbjct: 1203 CSLSDNLCRNGKCVNMIGTYQCS----CNPG---YQATPDRQGCTDIDECMIMNGGCDTQ 1255
Query: 331 SKVCDKHVDCPNFEDE---PRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL 384
+ +C E P R C + +ECE N C +C + P Y C C G+
Sbjct: 1256 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 1315
Query: 385 -IDNRTCEDIDECADPGSCSQI--CINEKGTFKCECHTGYA 422
+D +TC D++EC + C N KG+F C C GY+
Sbjct: 1316 SMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS 1356
Score = 48.8 bits (111), Expect = 7e-05
Identities = 54/221 (24%), Positives = 84/221 (38%), Gaps = 21/221 (9%)
Query: 216 DEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR- 274
D C+ P V S + + + + + C H + E GN TC+
Sbjct: 1891 DRNECLEIPNVCSHGLCVDLQGSYQCIC-HNGFKASQDQTMCMDVDECERHPCGNGTCKN 1949
Query: 275 -LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
+ + C C PG + DC D DE + + + R + G C+
Sbjct: 1950 TVGSYNCL---CYPGFELTHN-NDCLD-IDECSSFFGQVCRNGRCFNEIGSFKCL----- 1999
Query: 334 CDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCED 392
C++ + + ++ NEC G CS C + + C C GY+ + + C D
Sbjct: 2000 CNEGYE---LTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE-VKSENCID 2055
Query: 393 IDEC-ADPGSCS-QICINEKGTFKCECHTGYARDPRDRTRC 431
I+EC DP C C N G F+C C G+ R RC
Sbjct: 2056 INECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGR-RC 2095
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 354 NECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCS--QICIN 408
+ECE C C++ P + C C +G+ + + C D+DEC++ CS C+N
Sbjct: 1368 DECEIGAHNCDMHASCLNIPGSFKCSCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVN 1426
Query: 409 EKGTFKCECHTGYARD 424
G+++C C G+ D
Sbjct: 1427 TPGSYRCACSEGFTGD 1442
Score = 41.5 bits (93), Expect = 0.011
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 378 CEKGY-KLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGY 421
C +G+ I C+D+DEC A PG C CIN G+F+C C G+
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGH 306
Score = 41.5 bits (93), Expect = 0.011
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Query: 349 DRCGE--NECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDEC-ADPGSCSQ 404
D C E ++CE C + + T + C C G + D C D +EC PG C
Sbjct: 2295 DECAEGLHDCESRGMMC-KNLIGT---FMCICPPGMARRPDGEGCVDENECRTKPGICEN 2350
Query: 405 -ICINEKGTFKCECHTGY 421
C+N G+++CEC+ G+
Sbjct: 2351 GRCVNIIGSYRCECNEGF 2368
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC A PG C+ C N G+FKC C++G+A D +R
Sbjct: 1071 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 1110
Score = 37.5 bits (83), Expect = 0.18
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 20/147 (13%)
Query: 23 CTSSEFRCK-TGRCI--PLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
C++ +C +C+ P S++C CS+ D C+ C E C +G C
Sbjct: 1411 CSNGTHQCSINAQCVNTPGSYRCA----CSEGFTGDGFTCSDVDE-CAENINLC-ENGQC 1464
Query: 80 --IPRSWRCDATADCPDGSDEHQC-EVEACGPEEF----TCRGKPGECVPLTWMCDDNPD 132
+P ++RC+ SD C +++ C + TC PG +CDD +
Sbjct: 1465 LNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSGTCNNLPG---MFHCICDDGYE 1521
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCI 159
+ C +D C NG C+
Sbjct: 1522 LDRTGGNCTDIDEC-ADPINCVNGLCV 1547
Score = 37.1 bits (82), Expect = 0.23
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 20/135 (14%)
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRT 318
E ++ C GN C Q C++ I G C CP G ++N + C
Sbjct: 2612 EDVDECDGNHRC---QHGCQN---ILGGYRCG----CPQGYIQHYQWNQCVDENECSNPN 2661
Query: 319 EFDCGGGMCIPLSKVCDKHVDCPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYY 375
CG C + + CP+ F D+ C + NEC + C+ C +T GY
Sbjct: 2662 A--CGSASCY--NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYL 2717
Query: 376 CDCEKGYKLIDNRTC 390
C C GY + C
Sbjct: 2718 CGCPPGYYRVGQGHC 2732
Score = 36.3 bits (80), Expect = 0.41
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCS-QRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
P +E + + NEC+++ C C +TP G+ C C G+ L DN R C D
Sbjct: 2044 PGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2097
Score = 34.7 bits (76), Expect = 1.2
Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 14/110 (12%)
Query: 322 CGGGMCIPLSKVCDKHVDCP--NFEDEPRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCD 377
C GG CI + V CP + + E +C + +EC G C C +T Y+C
Sbjct: 286 CQGGNCI--NTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 343
Query: 378 CEKGY-------KLIDNRTCEDIDECADPGSCSQICINEKGTFKCECHTG 420
C +GY + ID RT + G C+Q +C C G
Sbjct: 344 CPRGYVTSTDGSRCIDQRTGMCFSGLVN-GRCAQELPGRMTKMQCCCEPG 392
Score = 33.5 bits (73), Expect = 2.9
Identities = 29/139 (20%), Positives = 52/139 (37%), Gaps = 11/139 (7%)
Query: 30 CKTGRCIPL--SWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
C G C + S++C+ C++ + P + C + C + S+ C
Sbjct: 2222 CGNGTCTNVIGSFECN----CNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECT 2277
Query: 88 ATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL--TWMCDDNPDCSDGSDEKAC-- 142
D+ C +++ C C + C L T+MC P + D + C
Sbjct: 2278 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2337
Query: 143 NETCRSDEFTCGNGKCIQM 161
CR+ C NG+C+ +
Sbjct: 2338 ENECRTKPGICENGRCVNI 2356
Score = 32.3 bits (70), Expect = 6.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 353 ENECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CED 392
ENEC G C RCV+ Y C+C +G++ + T C D
Sbjct: 2338 ENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLD 2379
>BC088378-1|AAH88378.1| 377|Homo sapiens LRP10 protein protein.
Length = 377
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/108 (37%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 41 KCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGL-----CIPRSWRCDATADCPDG 95
+CD DC+D +DE+ C C F C + G C + RC+ C DG
Sbjct: 1 RCDGSWDCADGTDEED--CPG----CPPGHFPCGAAGTSGATACYLPADRCNYQTFCADG 54
Query: 96 SDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
+DE +C C P F CR + +CV TW+CD PDC+DGSDE C+
Sbjct: 55 ADERRCR--HCQPGNFRCRDE--KCVYETWVCDGQPDCADGSDEWDCS 98
Score = 60.9 bits (141), Expect = 2e-08
Identities = 36/100 (36%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 127 CDDNPDCSDGSDEKACNETCRSDEFTCGNG------KCIQMRWVXXXXXXXXXXXXEVKC 180
CD + DC+DG+DE+ C C F CG C E +C
Sbjct: 2 CDGSWDCADGTDEEDC-PGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC 60
Query: 181 PTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGC 220
CQP +F C D +C+ W CDG DCADGSDE C
Sbjct: 61 RH--CQP-GNFRCRDEKCVYETWVCDGQPDCADGSDEWDC 97
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTC--RGKPGE--CVPLTWMCDDNPDCSDGSDEK 140
RCD + DC DG+DE C C P F C G G C C+ C+DG+DE+
Sbjct: 1 RCDGSWDCADGTDEEDCP--GCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGADER 58
Query: 141 ACNETCRSDEFTCGNGKCIQMRWV 164
C C+ F C + KC+ WV
Sbjct: 59 RCRH-CQPGNFRCRDEKCVYETWV 81
Score = 59.3 bits (137), Expect = 5e-08
Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 7/104 (6%)
Query: 205 CDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEAL 264
CDG DCADG+DE C P PC + + C A E
Sbjct: 2 CDGSWDCADGTDEEDCPGCPPGHFPCGAAG--TSGATACYLPADRCNYQTFCADGADE-- 57
Query: 265 ELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCT 308
CR C+ F+C+D C+ C+G DC DGSDE++C+
Sbjct: 58 RRCRH---CQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCS 98
Score = 44.4 bits (100), Expect = 0.002
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 21 RTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDE 54
R C FRC+ +C+ +W CD + DC+D SDE
Sbjct: 61 RHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDE 94
Score = 33.5 bits (73), Expect = 2.9
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 284 SCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF 343
+C A CN C DG+DE C C F C C+ + VCD DC +
Sbjct: 37 ACYLPADRCNYQTFCADGADERRCRH----CQPGN-FRCRDEKCVYETWVCDGQPDCADG 91
Query: 344 EDE 346
DE
Sbjct: 92 SDE 94
Score = 32.3 bits (70), Expect = 6.6
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
Query: 183 PTCQPQSHFSC----TDGQ--CISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFE 236
P C P HF C T G C C+ CADG+DE C C F
Sbjct: 18 PGCPP-GHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRC-------RHCQPGNFR 69
Query: 237 CNDRITCVHRAWV 249
C D CV+ WV
Sbjct: 70 CRDE-KCVYETWV 81
>BC007408-1|AAH07408.1| 770|Homo sapiens low density lipoprotein
receptor-related protein 3 protein.
Length = 770
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATK---MVCQEYRFEC--LSD 76
+C + EFRC G+C+P W+C+ +C D SDE A++ +C F C
Sbjct: 165 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
C+P RCD DC DGSDE C ACG
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGCPDLACG 255
Score = 68.9 bits (161), Expect = 6e-11
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 74 LSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
L D C RCD C G DE C AC P+++ C G G C C++ C
Sbjct: 386 LGDQGCFSEPQRCDGWWHCASGRDEQGC--PACPPDQYPCEGGSGLCYTPADRCNNQKSC 443
Query: 134 SDGSDEKACNETCRSDEFTCGNGKCIQMRW 163
DG+DEK C +C+ F CG CI W
Sbjct: 444 PDGADEKNC-FSCQPGTFHCGTNLCIFETW 472
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA-------CGPEEFTCRG-KP 117
CQ F C +G C+P W+C+ +C DGSDE C A C F C G +
Sbjct: 166 CQADEFRC-DNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 118 GECVPLTWMCDDNPDCSDGSDEKAC 142
C+P+ CD DC DGSDE C
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGC 249
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK-----TICDKRTEFDCG 323
G +C+ D+F+C + C+PG CN V +C DGSDE NC+ ++C T F C
Sbjct: 162 GQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGT-FPCS 220
Query: 324 GG---MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
G C+P+ + CD DC + DE C + C + G
Sbjct: 221 GARSTRCLPVERRCDGLQDCGDGSDEA--GCPDLACGRRLG 259
Score = 64.5 bits (150), Expect = 1e-09
Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 9/81 (11%)
Query: 23 CTSSEFRCK--TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
C ++ C+ +G C + +C+N+K C D +DE C + CQ F C LCI
Sbjct: 416 CPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKN--CFS----CQPGTFHC-GTNLCI 468
Query: 81 PRSWRCDATADCPDGSDEHQC 101
+WRCD DC DGSDEH C
Sbjct: 469 FETWRCDGQEDCQDGSDEHGC 489
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/123 (32%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 104 EACGPEEFTCRGKPGE--CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTC--GNGKCI 159
+ CG + G G+ C CD C+ G DE+ C C D++ C G+G C
Sbjct: 373 QPCGSSSDSDGGSLGDQGCFSEPQRCDGWWHCASGRDEQGC-PACPPDQYPCEGGSGLCY 431
Query: 160 QMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVG 219
E C + CQP + F C CI W CDG DC DGSDE G
Sbjct: 432 TPADRCNNQKSCPDGADEKNCFS--CQPGT-FHCGTNLCIFETWRCDGQEDCQDGSDEHG 488
Query: 220 CVS 222
C++
Sbjct: 489 CLA 491
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 145 TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH------FSCTDG-- 196
+C++DEF C NGKC+ W E C P +P F C+
Sbjct: 165 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 197 -QCISAWWHCDGDVDCADGSDEVGC 220
+C+ CDG DC DGSDE GC
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGC 249
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/81 (39%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 268 RGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
+G C DQ+ C+ S C A CN K CPDG+DE NC C T F CG
Sbjct: 411 QGCPACPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNCFS----CQPGT-FHCGTN 465
Query: 326 MCIPLSKVCDKHVDCPNFEDE 346
+CI + CD DC + DE
Sbjct: 466 LCIFETWRCDGQEDCQDGSDE 486
Score = 49.6 bits (113), Expect = 4e-05
Identities = 37/116 (31%), Positives = 46/116 (39%), Gaps = 11/116 (9%)
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
S D C S CDG CA G DE GC + P + PC C T R
Sbjct: 385 SLGDQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGSGLC---YTPADRC---- 437
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
A E + +C+ F C + CI C+G +DC DGSDE+ C
Sbjct: 438 --NNQKSCPDGADE--KNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGC 489
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/65 (30%), Positives = 29/65 (44%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
+C F C T CI +W+CD ++DC D SDE + + V L GL +
Sbjct: 454 SCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLV 513
Query: 82 RSWRC 86
+ C
Sbjct: 514 IALGC 518
Score = 41.5 bits (93), Expect = 0.011
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECN 238
+CQ F C +G+C+ W C+ +C DGSDE C S P P C F C+
Sbjct: 165 SCQADE-FRCDNGKCLPGPWQCNTVDECGDGSDEGNC-SAPASEPPGSLCPGGTFPCS 220
Score = 41.1 bits (92), Expect = 0.014
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
+C +EF C G+C+P W C+ +C DGSDE C+
Sbjct: 165 SCQADEFRCDN--GKCLPGPWQCNTVDECGDGSDEGNCS 201
Score = 32.7 bits (71), Expect = 5.0
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 7/67 (10%)
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC--GGGMCIPLSKVCDKHVD 339
D C C+G C G DE C C ++ C G G+C + C+
Sbjct: 388 DQGCFSEPQRCDGWWHCASGRDEQGC----PACPP-DQYPCEGGSGLCYTPADRCNNQKS 442
Query: 340 CPNFEDE 346
CP+ DE
Sbjct: 443 CPDGADE 449
>AK129963-1|BAC85262.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ26453 fis, clone KDN03319, highly similar to
Homo sapiens immunoglobulin superfamily, member 1
(IGSF1). ).
Length = 284
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATK---MVCQEYRFEC--LSD 76
+C + EFRC G+C+P W+C+ +C D SDE A++ +C F C
Sbjct: 39 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
C+P RCD DC DGSDE C ACG
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGCPDLACG 129
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA-------CGPEEFTCRG-KP 117
CQ F C +G C+P W+C+ +C DGSDE C A C F C G +
Sbjct: 40 CQADEFRC-DNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 118 GECVPLTWMCDDNPDCSDGSDEKAC 142
C+P+ CD DC DGSDE C
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGC 123
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK-----TICDKRTEFDCG 323
G +C+ D+F+C + C+PG CN V +C DGSDE NC+ ++C T F C
Sbjct: 36 GQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGT-FPCS 94
Query: 324 GG---MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
G C+P+ + CD DC + DE C + C + G
Sbjct: 95 GARSTRCLPVERRCDGLQDCGDGSDEA--GCPDLACGRRLG 133
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 145 TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH------FSCTDG-- 196
+C++DEF C NGKC+ W E C P +P F C+
Sbjct: 39 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 197 -QCISAWWHCDGDVDCADGSDEVGC 220
+C+ CDG DC DGSDE GC
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGC 123
Score = 41.5 bits (93), Expect = 0.011
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECN 238
+CQ F C +G+C+ W C+ +C DGSDE C S P P C F C+
Sbjct: 39 SCQADE-FRCDNGKCLPGPWQCNTVDECGDGSDEGNC-SAPASEPPGSLCPGGTFPCS 94
Score = 41.1 bits (92), Expect = 0.014
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
+C +EF C G+C+P W C+ +C DGSDE C+
Sbjct: 39 SCQADEFRCDN--GKCLPGPWQCNTVDECGDGSDEGNCS 75
>AK126750-1|BAC86671.1| 644|Homo sapiens protein ( Homo sapiens
cDNA FLJ44797 fis, clone BRACE3040644, highly similar
to Homo sapiens low density lipoprotein receptor-related
protein 3 (LRP3). ).
Length = 644
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATK---MVCQEYRFEC--LSD 76
+C + EFRC G+C+P W+C+ +C D SDE A++ +C F C
Sbjct: 39 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
C+P RCD DC DGSDE C ACG
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGCPDLACG 129
Score = 68.5 bits (160), Expect = 8e-11
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 74 LSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
L D C RCD C G DE C AC P+++ C G G C C++ C
Sbjct: 260 LGDQGCFSEPQRCDGWWHCASGRDEQGC--PACPPDQYPCEGGGGLCYTPADRCNNQKSC 317
Query: 134 SDGSDEKACNETCRSDEFTCGNGKCIQMRW 163
DG+DEK C +C+ F CG CI W
Sbjct: 318 PDGADEKNC-FSCQPGTFHCGTNLCIFETW 346
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA-------CGPEEFTCRG-KP 117
CQ F C +G C+P W+C+ +C DGSDE C A C F C G +
Sbjct: 40 CQADEFRC-DNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 118 GECVPLTWMCDDNPDCSDGSDEKAC 142
C+P+ CD DC DGSDE C
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGC 123
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK-----TICDKRTEFDCG 323
G +C+ D+F+C + C+PG CN V +C DGSDE NC+ ++C T F C
Sbjct: 36 GQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGT-FPCS 94
Query: 324 GG---MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
G C+P+ + CD DC + DE C + C + G
Sbjct: 95 GARSTRCLPVERRCDGLQDCGDGSDEA--GCPDLACGRRLG 133
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/123 (32%), Positives = 51/123 (41%), Gaps = 8/123 (6%)
Query: 104 EACGPEEFTCRGKPGE--CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTC--GNGKCI 159
+ CG + G G+ C CD C+ G DE+ C C D++ C G G C
Sbjct: 247 QPCGSSSDSDGGSLGDQGCFSEPQRCDGWWHCASGRDEQGC-PACPPDQYPCEGGGGLCY 305
Query: 160 QMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVG 219
E C + CQP + F C CI W CDG DC DGSDE G
Sbjct: 306 TPADRCNNQKSCPDGADEKNCFS--CQPGT-FHCGTNLCIFETWRCDGQEDCQDGSDEHG 362
Query: 220 CVS 222
C++
Sbjct: 363 CLA 365
Score = 63.3 bits (147), Expect = 3e-09
Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 9/81 (11%)
Query: 23 CTSSEFRCKTGR--CIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
C ++ C+ G C + +C+N+K C D +DE C + CQ F C LCI
Sbjct: 290 CPPDQYPCEGGGGLCYTPADRCNNQKSCPDGADEKN--CFS----CQPGTFHC-GTNLCI 342
Query: 81 PRSWRCDATADCPDGSDEHQC 101
+WRCD DC DGSDEH C
Sbjct: 343 FETWRCDGQEDCQDGSDEHGC 363
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 145 TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH------FSCTDG-- 196
+C++DEF C NGKC+ W E C P +P F C+
Sbjct: 39 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 98
Query: 197 -QCISAWWHCDGDVDCADGSDEVGC 220
+C+ CDG DC DGSDE GC
Sbjct: 99 TRCLPVERRCDGLQDCGDGSDEAGC 123
Score = 53.2 bits (122), Expect = 3e-06
Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 268 RGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
+G C DQ+ C+ C A CN K CPDG+DE NC C T F CG
Sbjct: 285 QGCPACPPDQYPCEGGGGLCYTPADRCNNQKSCPDGADEKNCFS----CQPGT-FHCGTN 339
Query: 326 MCIPLSKVCDKHVDCPNFEDE 346
+CI + CD DC + DE
Sbjct: 340 LCIFETWRCDGQEDCQDGSDE 360
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/116 (31%), Positives = 46/116 (39%), Gaps = 11/116 (9%)
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
S D C S CDG CA G DE GC + P + PC C T R
Sbjct: 259 SLGDQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGGGLC---YTPADRC---- 311
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
A E + +C+ F C + CI C+G +DC DGSDE+ C
Sbjct: 312 --NNQKSCPDGADE--KNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGC 363
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/65 (30%), Positives = 29/65 (44%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
+C F C T CI +W+CD ++DC D SDE + + V L GL +
Sbjct: 328 SCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLV 387
Query: 82 RSWRC 86
+ C
Sbjct: 388 IALGC 392
Score = 41.5 bits (93), Expect = 0.011
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECN 238
+CQ F C +G+C+ W C+ +C DGSDE C S P P C F C+
Sbjct: 39 SCQADE-FRCDNGKCLPGPWQCNTVDECGDGSDEGNC-SAPASEPPGSLCPGGTFPCS 94
Score = 41.1 bits (92), Expect = 0.014
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
+C +EF C G+C+P W C+ +C DGSDE C+
Sbjct: 39 SCQADEFRCDN--GKCLPGPWQCNTVDECGDGSDEGNCS 75
Score = 35.1 bits (77), Expect = 0.94
Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC--GGGMCIPLSKVCDKHVD 339
D C C+G C G DE C C ++ C GGG+C + C+
Sbjct: 262 DQGCFSEPQRCDGWWHCASGRDEQGC----PACPP-DQYPCEGGGGLCYTPADRCNNQKS 316
Query: 340 CPNFEDE 346
CP+ DE
Sbjct: 317 CPDGADE 323
>AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens
cDNA FLJ32009 fis, clone NT2RP7009498, weakly similar to
FIBULIN-1, ISOFORM A PRECURSOR. ).
Length = 955
Score = 74.1 bits (174), Expect = 2e-12
Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 13/156 (8%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKR-TEFDCGGGMC 327
G+ T L F C CI V C DG C C + + C G C
Sbjct: 64 GHCTLPLCSFGCGSGICI-----APNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGC 118
Query: 328 IPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-I 385
+++VC V E RC + +EC ++ C CV+T G+ C+C G +L
Sbjct: 119 QEVARVCP--VGFSMTEAAVGIRCTDIDECVTSS--CEGHCVNTEGGFVCECGPGMQLSA 174
Query: 386 DNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
D +C+D DEC C Q C N G++KC C TG+
Sbjct: 175 DRHSCQDTDECLGT-PCQQRCKNSIGSYKCSCRTGF 209
Score = 56.4 bits (130), Expect = 4e-07
Identities = 29/75 (38%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKLIDNR-TCEDIDECADP---GSCSQICINEKGTFKCECH 418
C QRC ++ Y C C G+ L NR +C D++EC P C C N G+F C C
Sbjct: 190 CQQRCKNSIGSYKCSCRTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCR 249
Query: 419 TGYARDPRDRTRCKA 433
G+ R DR C+A
Sbjct: 250 PGF-RLRADRVSCEA 263
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 18/160 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMC 327
C + C+ +C+ G+ C DCP G E + +R+ + C G C
Sbjct: 226 CERNPLLCRGGTCVNTEGSFQC----DCPLGH-ELSPSREDCVDINECSLSDNLCRNGKC 280
Query: 328 IPLSKVCDKHVDC-PNFEDEP-RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL 384
+ + + C P ++ P R C + +EC NGGC +C ++ Y C C +GY L
Sbjct: 281 VNM--IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 338
Query: 385 I-DNRTCEDIDECA-DPGSC-SQICINEKGTFKCECHTGY 421
+ D R+C DIDEC +P C C N G ++C C+ G+
Sbjct: 339 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF 378
Score = 73.7 bits (173), Expect = 2e-12
Identities = 51/165 (30%), Positives = 70/165 (42%), Gaps = 11/165 (6%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
CR+ C C+ PG+ C + G C+ R C GG C+
Sbjct: 183 CRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECE-RNPLLCRGGTCVNT 241
Query: 331 SKVCDKHVDCP-NFEDEP-RDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI- 385
DCP E P R+ C + NEC ++ C +CV+ Y C C GY+
Sbjct: 242 EG--SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 299
Query: 386 DNRTCEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
D + C DIDEC G C C N +G+++C C GYA P R+
Sbjct: 300 DRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRS 344
Score = 70.9 bits (166), Expect = 2e-11
Identities = 53/156 (33%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 280 CKDHSCI--PGALYCNGVKDCPDGSD-EYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDK 336
C + CI G+ C +CP G + +Y R + CG G C + +
Sbjct: 1246 CSNGQCINTDGSFRC----ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNV--IGSF 1299
Query: 337 HVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDI 393
+C FE P C + NEC +N C+ RC++T Y C C GY L D + C+D+
Sbjct: 1300 ECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDL 1359
Query: 394 DECA----DPGSCSQICINEKGTFKCECHTGYARDP 425
DECA D S +C N GTF C C G AR P
Sbjct: 1360 DECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRP 1395
Score = 70.5 bits (165), Expect = 2e-11
Identities = 39/122 (31%), Positives = 67/122 (54%), Gaps = 20/122 (16%)
Query: 322 CGGGMCIPLSKVCDKHVDCP---NFED-----EPRDRC--GENECEKNNGGCSQRCVDTP 371
C G+CI +++ +CP ++ D E D C G+N C++N C+++P
Sbjct: 883 CANGVCI--NQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD-----CINSP 935
Query: 372 IGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
Y C+C G+KL N C D +EC + P CS +C++ +G+++C CH G+ + +D+T
Sbjct: 936 GSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF-KASQDQT 994
Query: 430 RC 431
C
Sbjct: 995 MC 996
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSC-SQICINE 409
NEC+ G C+ +C +T + C C G+ L ++ R C DIDEC P C S IC+N
Sbjct: 139 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNT 198
Query: 410 KGTFKCECHTGY 421
G+F+CEC GY
Sbjct: 199 PGSFECECFEGY 210
Score = 62.9 bits (146), Expect = 4e-09
Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQICINEKG 411
+EC ++ C+ C +T Y C C +GY L D +TC+D+DEC +C +C+N G
Sbjct: 1557 DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLG 1616
Query: 412 TFKCECHTGYAR 423
F C+C G+ +
Sbjct: 1617 GFTCKCPPGFTQ 1628
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 298 CPDGSDEYNC-TRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENEC 356
C S N T+ + CD + +C PL CP+ D +EC
Sbjct: 1459 CQMASSSRNLVTKSECCCDGGRGWGHQCELC-PLPGTAQYKKICPHGPGYTTDGRDIDEC 1517
Query: 357 EKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINEKGTF 413
+ C+ +C++T + C C+ GY I +C D+DEC+ P C+ IC N +G++
Sbjct: 1518 KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSY 1577
Query: 414 KCECHTGYARDPRDRTRCK 432
+C C GY +T CK
Sbjct: 1578 QCSCPRGYVLQEDGKT-CK 1595
Score = 60.5 bits (140), Expect = 2e-08
Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 23/171 (13%)
Query: 280 CKD-HSCIPGALYCNGVKDCPDGSDEYNCT-------RQKTICDKRTEF-----DCGGGM 326
C+D C G C DC + Y C C R E C G+
Sbjct: 912 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL 971
Query: 327 CIPL--SKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
C+ L S C H +D+ C + +ECE++ G + C +T Y C C G++
Sbjct: 972 CVDLQGSYQCICHNGFKASQDQTM--CMDVDECERHPCG-NGTCKNTVGSYNCLCYPGFE 1028
Query: 384 LIDNRTCEDIDECAD--PGSC-SQICINEKGTFKCECHTGYARDPRDRTRC 431
L N C DIDEC+ C + C NE G+FKC C+ GY P D C
Sbjct: 1029 LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTP-DGKNC 1078
Score = 59.7 bits (138), Expect = 4e-08
Identities = 86/375 (22%), Positives = 136/375 (36%), Gaps = 55/375 (14%)
Query: 86 CDATADCPDGSDEHQCEVEACG---PEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKAC 142
C +C G+ H C++ A P F C + G + C D +CS+G+ + +
Sbjct: 429 CTDVDECEIGA--HNCDMHASCLNIPGSFKCSCREG-WIGNGIKCIDLDECSNGTHQCSI 485
Query: 143 NETCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISA- 201
N C + T G+ +C +V C + C +GQC++
Sbjct: 486 NAQCVN---TPGSYRCA----CSEGFTGDGFTCSDVD----ECAENINL-CENGQCLNVP 533
Query: 202 -WWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXX 260
+ C+ ++ SD C + I CN+ H
Sbjct: 534 GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGN 593
Query: 261 XEALELCRGNVTC-------RLDQFQCK---DHSCIPGALYC--NGVKDC-----PDGSD 303
++ C + C +++C D P + C N V +C P G
Sbjct: 594 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 653
Query: 304 EYNCTRQKTICDKRTEFDCGGGM--------CIPLSKVCDKHVDCPN---FEDEPRDRCG 352
+C + + R+ C G C P++ + + CP F P
Sbjct: 654 SLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNST-EYYTLCPGGEGFRPNPITIIL 712
Query: 353 EN--ECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-IC 406
E+ EC++ G C C++T + C+C +GY L D R CEDIDEC A PG C C
Sbjct: 713 EDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTC 772
Query: 407 INEKGTFKCECHTGY 421
N G + C C Y
Sbjct: 773 YNTLGNYTCICPPEY 787
Score = 59.3 bits (137), Expect = 5e-08
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 12/127 (9%)
Query: 305 YNCTRQKTIC---DKRTEFDCGGGMCIPLSKVCDKHVDC-PNFEDEPRDRCGE-NECEKN 359
+ ++ +T+C D+ CG G C + V + C P FE + C + +EC
Sbjct: 987 FKASQDQTMCMDVDECERHPCGNGTC--KNTVGSYNCLCYPGFELTHNNDCLDIDECSSF 1044
Query: 360 NGGCSQ--RCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGSCSQ-ICINEKGTFK 414
G + RC + + C C +GY+L D + C D +EC A PGSCS C N +G+F+
Sbjct: 1045 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFR 1104
Query: 415 CECHTGY 421
C C GY
Sbjct: 1105 CICPPGY 1111
Score = 58.8 bits (136), Expect = 7e-08
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 16/162 (9%)
Query: 273 CRLDQFQCKDHS-CI--PGALYCNGVKDCPDG--SDEYNCTRQKTICDKRTEFDCGGGMC 327
C QC ++ C+ PG+ C C +G D + C+ C + C G C
Sbjct: 476 CSNGTHQCSINAQCVNTPGSYRCA----CSEGFTGDGFTCSDVDE-CAENINL-CENGQC 529
Query: 328 --IPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI 385
+P + C+ + D R +EC N C + P ++C C+ GY+L
Sbjct: 530 LNVPGAYRCECEMGFTPASDS-RSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELD 588
Query: 386 -DNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARDP 425
C DIDECADP +C + +C+N G ++C C + +P
Sbjct: 589 RTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNP 630
Score = 58.4 bits (135), Expect = 9e-08
Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Query: 272 TCR-LDQFQCKDHSCIPGALYCNG--VKDCPDG-SDEYNCTRQKTICDKRTEFDCGG-GM 326
TC+ LD+ Q K H+C + G CP G + + C + CG G+
Sbjct: 1593 TCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSL-CGAKGI 1651
Query: 327 C--IPLSKVCDKHVDCPNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGY 382
C P S C+ F D C + +EC+ N+ C C + GY C C +GY
Sbjct: 1652 CQNTPGSFSCECQ---RGFSLDATGLNCEDVDECDGNHR-CQHGCQNILGGYRCGCPQGY 1707
Query: 383 -KLIDNRTCEDIDECADPGSC-SQICINEKGTFKCECHTGYARD 424
+ C D +EC++P +C S C N G++KC C +G++ D
Sbjct: 1708 IQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFD 1751
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 322 CGGGMCIPLSKVCDKHVDCP-NFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDC 378
C G CI +CP + D RC + +EC N + C + + C+C
Sbjct: 1246 CSNGQCINTDG--SFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNC 1303
Query: 379 EKGYKLIDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
+G++ CEDI+ECA +P C+ C+N G+++C C GYA D+ CK
Sbjct: 1304 NEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYAL-REDQKMCK 1357
Score = 52.4 bits (120), Expect = 6e-06
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Query: 354 NECEKNNGGCS-QRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECA-DPGSCSQ--ICIN 408
NEC+ N+ C C +T + C C+ GY + T C D+DEC +C C+N
Sbjct: 391 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 450
Query: 409 EKGTFKCECHTGY 421
G+FKC C G+
Sbjct: 451 IPGSFKCSCREGW 463
Score = 52.4 bits (120), Expect = 6e-06
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 353 ENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLID-NRTCEDIDECADPGS-CSQICINEK 410
ENEC N S C +T Y C C G+ + C D++EC+ + C+ C N +
Sbjct: 1719 ENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTE 1778
Query: 411 GTFKCECHTGYAR 423
G + C C GY R
Sbjct: 1779 GGYLCGCPPGYYR 1791
Score = 51.2 bits (117), Expect = 1e-05
Identities = 45/161 (27%), Positives = 64/161 (39%), Gaps = 18/161 (11%)
Query: 273 CRLDQFQCKDHSCIP--GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L C++ C+ G C+ C G Y T + C E G C
Sbjct: 268 CSLSDNLCRNGKCVNMIGTYQCS----CNPG---YQATPDRQGCTDIDECMIMNGGCDTQ 320
Query: 331 SKVCDKHVDCPNFEDE---PRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL 384
+ +C E P R C + +ECE N C +C + P Y C C G+
Sbjct: 321 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 380
Query: 385 -IDNRTCEDIDECADPGSCSQI--CINEKGTFKCECHTGYA 422
+D +TC D++EC + C N KG+F C C GY+
Sbjct: 381 SMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS 421
Score = 48.8 bits (111), Expect = 7e-05
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C +G I TCED++EC PG C C+N KG+F CEC G D R
Sbjct: 5 CPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGR 57
Score = 48.8 bits (111), Expect = 7e-05
Identities = 54/221 (24%), Positives = 84/221 (38%), Gaps = 21/221 (9%)
Query: 216 DEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCR- 274
D C+ P V S + + + + + C H + E GN TC+
Sbjct: 956 DRNECLEIPNVCSHGLCVDLQGSYQCIC-HNGFKASQDQTMCMDVDECERHPCGNGTCKN 1014
Query: 275 -LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
+ + C C PG + DC D DE + + + R + G C+
Sbjct: 1015 TVGSYNCL---CYPGFELTHN-NDCLD-IDECSSFFGQVCRNGRCFNEIGSFKCL----- 1064
Query: 334 CDKHVDCPNFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRTCED 392
C++ + + ++ NEC G CS C + + C C GY+ + + C D
Sbjct: 1065 CNEGYE---LTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE-VKSENCID 1120
Query: 393 IDEC-ADPGSCS-QICINEKGTFKCECHTGYARDPRDRTRC 431
I+EC DP C C N G F+C C G+ R RC
Sbjct: 1121 INECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGR-RC 1160
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 354 NECEKNNGGCSQR--CVDTPIGYYCDCEKGYKLIDNRTCEDIDECAD-PGSCS--QICIN 408
+ECE C C++ P + C C +G+ + + C D+DEC++ CS C+N
Sbjct: 433 DECEIGAHNCDMHASCLNIPGSFKCSCREGW-IGNGIKCIDLDECSNGTHQCSINAQCVN 491
Query: 409 EKGTFKCECHTGYARD 424
G+++C C G+ D
Sbjct: 492 TPGSYRCACSEGFTGD 507
Score = 41.5 bits (93), Expect = 0.011
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Query: 349 DRCGE--NECEKNNGGCSQRCVDTPIGYYCDCEKGY-KLIDNRTCEDIDEC-ADPGSCSQ 404
D C E ++CE C + + T + C C G + D C D +EC PG C
Sbjct: 1360 DECAEGLHDCESRGMMC-KNLIGT---FMCICPPGMARRPDGEGCVDENECRTKPGICEN 1415
Query: 405 -ICINEKGTFKCECHTGY 421
C+N G+++CEC+ G+
Sbjct: 1416 GRCVNIIGSYRCECNEGF 1433
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 391 EDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC A PG C+ C N G+FKC C++G+A D +R
Sbjct: 136 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER 175
Score = 37.5 bits (83), Expect = 0.18
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 20/147 (13%)
Query: 23 CTSSEFRCK-TGRCI--PLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLC 79
C++ +C +C+ P S++C CS+ D C+ C E C +G C
Sbjct: 476 CSNGTHQCSINAQCVNTPGSYRCA----CSEGFTGDGFTCSDVDE-CAENINLC-ENGQC 529
Query: 80 --IPRSWRCDATADCPDGSDEHQC-EVEACGPEEF----TCRGKPGECVPLTWMCDDNPD 132
+P ++RC+ SD C +++ C + TC PG +CDD +
Sbjct: 530 LNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPG---MFHCICDDGYE 586
Query: 133 CSDGSDEKACNETCRSDEFTCGNGKCI 159
+ C +D C NG C+
Sbjct: 587 LDRTGGNCTDIDEC-ADPINCVNGLCV 612
Score = 37.1 bits (82), Expect = 0.23
Identities = 36/135 (26%), Positives = 52/135 (38%), Gaps = 20/135 (14%)
Query: 262 EALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRT 318
E ++ C GN C Q C++ I G C CP G ++N + C
Sbjct: 1677 EDVDECDGNHRC---QHGCQN---ILGGYRCG----CPQGYIQHYQWNQCVDENECSNPN 1726
Query: 319 EFDCGGGMCIPLSKVCDKHVDCPN-FE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYY 375
CG C + + CP+ F D+ C + NEC + C+ C +T GY
Sbjct: 1727 A--CGSASCY--NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYL 1782
Query: 376 CDCEKGYKLIDNRTC 390
C C GY + C
Sbjct: 1783 CGCPPGYYRVGQGHC 1797
Score = 36.3 bits (80), Expect = 0.41
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 341 PNFEDEPRDRCGENECEKNNGGCS-QRCVDTPIGYYCDCEKGYKLIDN-RTCED 392
P +E + + NEC+++ C C +TP G+ C C G+ L DN R C D
Sbjct: 1109 PGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 1162
Score = 33.5 bits (73), Expect = 2.9
Identities = 29/139 (20%), Positives = 52/139 (37%), Gaps = 11/139 (7%)
Query: 30 CKTGRCIPL--SWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIPRSWRCD 87
C G C + S++C+ C++ + P + C + C + S+ C
Sbjct: 1287 CGNGTCTNVIGSFECN----CNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECT 1342
Query: 88 ATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPL--TWMCDDNPDCSDGSDEKAC-- 142
D+ C +++ C C + C L T+MC P + D + C
Sbjct: 1343 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 1402
Query: 143 NETCRSDEFTCGNGKCIQM 161
CR+ C NG+C+ +
Sbjct: 1403 ENECRTKPGICENGRCVNI 1421
Score = 33.1 bits (72), Expect = 3.8
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLI-DNRTCEDI 393
NECE G C RCV++ ++C+C +G L R C DI
Sbjct: 21 NECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 62
Score = 32.3 bits (70), Expect = 6.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 353 ENECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CED 392
ENEC G C RCV+ Y C+C +G++ + T C D
Sbjct: 1403 ENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLD 1444
>AB009462-1|BAA32330.1| 770|Homo sapiens LDL receptor related
protein 105 protein.
Length = 770
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATK---MVCQEYRFEC--LSD 76
+C + EFRC G+C+P W+C+ +C D SDE A++ +C F C
Sbjct: 165 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 77 GLCIPRSWRCDATADCPDGSDEHQCEVEACG 107
C+P RCD DC DGSDE C ACG
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGCPDLACG 255
Score = 68.9 bits (161), Expect = 6e-11
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 74 LSDGLCIPRSWRCDATADCPDGSDEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDC 133
L D C RCD C G DE C AC P+++ C G G C C++ C
Sbjct: 386 LGDQGCFSEPQRCDGWWHCASGRDEQGC--PACPPDQYPCEGGSGLCYTPADRCNNQKSC 443
Query: 134 SDGSDEKACNETCRSDEFTCGNGKCIQMRW 163
DG+DEK C +C+ F CG CI W
Sbjct: 444 PDGADEKNC-FSCQPGTFHCGTNLCIFETW 472
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 66 CQEYRFECLSDGLCIPRSWRCDATADCPDGSDEHQCEVEA-------CGPEEFTCRG-KP 117
CQ F C +G C+P W+C+ +C DGSDE C A C F C G +
Sbjct: 166 CQADEFRC-DNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 118 GECVPLTWMCDDNPDCSDGSDEKAC 142
C+P+ CD DC DGSDE C
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGC 249
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQK-----TICDKRTEFDCG 323
G +C+ D+F+C + C+PG CN V +C DGSDE NC+ ++C T F C
Sbjct: 162 GQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGT-FPCS 220
Query: 324 GG---MCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNNG 361
G C+P+ + CD DC + DE C + C + G
Sbjct: 221 GARSTRCLPVERRCDGLQDCGDGSDEA--GCPDLACGRRLG 259
Score = 64.5 bits (150), Expect = 1e-09
Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 9/81 (11%)
Query: 23 CTSSEFRCK--TGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCI 80
C ++ C+ +G C + +C+N+K C D +DE C + CQ F C LCI
Sbjct: 416 CPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKN--CFS----CQPGTFHC-GTNLCI 468
Query: 81 PRSWRCDATADCPDGSDEHQC 101
+WRCD DC DGSDEH C
Sbjct: 469 FETWRCDGQEDCQDGSDEHGC 489
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/123 (32%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 104 EACGPEEFTCRGKPGE--CVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTC--GNGKCI 159
+ CG + G G+ C CD C+ G DE+ C C D++ C G+G C
Sbjct: 373 QPCGSSSDSDGGSLGDQGCFSEPQRCDGWWHCASGRDEQGC-PACPPDQYPCEGGSGLCY 431
Query: 160 QMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVG 219
E C + CQP + F C CI W CDG DC DGSDE G
Sbjct: 432 TPADRCNNQKSCPDGADEKNCFS--CQPGT-FHCGTNLCIFETWRCDGQEDCQDGSDEHG 488
Query: 220 CVS 222
C++
Sbjct: 489 CLA 491
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 145 TCRSDEFTCGNGKCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSH------FSCTDG-- 196
+C++DEF C NGKC+ W E C P +P F C+
Sbjct: 165 SCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARS 224
Query: 197 -QCISAWWHCDGDVDCADGSDEVGC 220
+C+ CDG DC DGSDE GC
Sbjct: 225 TRCLPVERRCDGLQDCGDGSDEAGC 249
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/81 (39%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 268 RGNVTCRLDQFQCKDHS--CIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGG 325
+G C DQ+ C+ S C A CN K CPDG+DE NC C T F CG
Sbjct: 411 QGCPACPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNCFS----CQPGT-FHCGTN 465
Query: 326 MCIPLSKVCDKHVDCPNFEDE 346
+CI + CD DC + DE
Sbjct: 466 LCIFETWRCDGQEDCQDGSDE 486
Score = 49.6 bits (113), Expect = 4e-05
Identities = 37/116 (31%), Positives = 46/116 (39%), Gaps = 11/116 (9%)
Query: 192 SCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHRAWVXX 251
S D C S CDG CA G DE GC + P + PC C T R
Sbjct: 385 SLGDQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGSGLC---YTPADRC---- 437
Query: 252 XXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNC 307
A E + +C+ F C + CI C+G +DC DGSDE+ C
Sbjct: 438 --NNQKSCPDGADE--KNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGC 489
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/65 (30%), Positives = 29/65 (44%)
Query: 22 TCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSDGLCIP 81
+C F C T CI +W+CD ++DC D SDE + + V L GL +
Sbjct: 454 SCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLV 513
Query: 82 RSWRC 86
+ C
Sbjct: 514 IALGC 518
Score = 41.5 bits (93), Expect = 0.011
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 184 TCQPQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSP---CISTEFECN 238
+CQ F C +G+C+ W C+ +C DGSDE C S P P C F C+
Sbjct: 165 SCQADE-FRCDNGKCLPGPWQCNTVDECGDGSDEGNC-SAPASEPPGSLCPGGTFPCS 220
Score = 41.1 bits (92), Expect = 0.014
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 105 ACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACN 143
+C +EF C G+C+P W C+ +C DGSDE C+
Sbjct: 165 SCQADEFRCDN--GKCLPGPWQCNTVDECGDGSDEGNCS 201
Score = 32.7 bits (71), Expect = 5.0
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 7/67 (10%)
Query: 282 DHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDC--GGGMCIPLSKVCDKHVD 339
D C C+G C G DE C C ++ C G G+C + C+
Sbjct: 388 DQGCFSEPQRCDGWWHCASGRDEQGC----PACPP-DQYPCEGGSGLCYTPADRCNNQKS 442
Query: 340 CPNFEDE 346
CP+ DE
Sbjct: 443 CPDGADE 449
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 218
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 219 NIPGDFECECPEGY 232
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 121 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 178
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 239 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 154 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 211
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 212 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 271
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 272 GFKLAQDQKSCEVVSVC 288
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 218
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 219 NIPGDFECECPEGY 232
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 121 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 178
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 239 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 154 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 211
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 212 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 271
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 272 GFKLAQDQKSCEVVSVC 288
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 133 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 192
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 193 NIPGDFECECPEGY 206
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 95 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 152
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 153 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 212
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 213 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 241
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 128 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 185
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 186 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 245
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 246 GFKLAQDQKSCEVVSVC 262
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 218
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 219 NIPGDFECECPEGY 232
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 121 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 178
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 239 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 154 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 211
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 212 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 271
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 272 GFKLAQDQKSCEVVSVC 288
>BC117322-1|AAI17323.1| 572|Homo sapiens TMPRSS7 protein protein.
Length = 572
Score = 73.7 bits (173), Expect = 2e-12
Identities = 45/131 (34%), Positives = 57/131 (43%), Gaps = 13/131 (9%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
++ S+ C FRC +G C+P + +CD DC D SDE C + + C F
Sbjct: 207 YNISQPCPVGSFRCSSGLCVPQAQRCDGVNDCFDESDE--LFCVSPQPACNTSSFR--QH 262
Query: 77 GLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
G I CD DC +G DE C + C F C G CD DC D
Sbjct: 263 GPLI-----CDGFRDCENGRDEQNCTQSIPCNNRTFKC-GNDICFRKQNAKCDGTVDCPD 316
Query: 136 GSDEKACNETC 146
GSDE+ C TC
Sbjct: 317 GSDEEGC--TC 325
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/123 (30%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHR 246
P F C+ G C+ CDG DC D SDE+ CVS + C ++ F + + C
Sbjct: 214 PVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSP---QPACNTSSFRQHGPLIC--- 267
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEY 305
+ C ++ C F+C + C C+G DCPDGSDE
Sbjct: 268 ------DGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEE 321
Query: 306 NCT 308
CT
Sbjct: 322 GCT 324
Score = 59.3 bits (137), Expect = 5e-08
Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 288 GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV-CDKHVDCPNFEDE 346
G L C+G +DC +G DE NCT Q C+ RT F CG +C CD VDCP+ DE
Sbjct: 263 GPLICDGFRDCENGRDEQNCT-QSIPCNNRT-FKCGNDICFRKQNAKCDGTVDCPDGSDE 320
Query: 347 PRDRCGEN 354
C +
Sbjct: 321 EGCTCSRS 328
Score = 50.0 bits (114), Expect = 3e-05
Identities = 37/113 (32%), Positives = 47/113 (41%), Gaps = 20/113 (17%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
C + F+C C+P A C+GV DC D SDE C + C+ + G PL
Sbjct: 213 CPVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSPQPACNTSSFRQHG-----PL-- 265
Query: 333 VCDKHVDCPNFEDEPR-----------DRCGENEC-EKNNGGCSQRCVDTPIG 373
+CD DC N DE +CG + C K N C VD P G
Sbjct: 266 ICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKC-DGTVDCPDG 317
Score = 46.4 bits (105), Expect = 4e-04
Identities = 37/119 (31%), Positives = 41/119 (34%), Gaps = 8/119 (6%)
Query: 104 EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR- 162
+ C F C G CVP CD DC D SDE C S + C Q
Sbjct: 211 QPCPVGSFRCSS--GLCVPQAQRCDGVNDCFDESDELFCV----SPQPACNTSSFRQHGP 264
Query: 163 WVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAW-WHCDGDVDCADGSDEVGC 220
+ E C F C + C CDG VDC DGSDE GC
Sbjct: 265 LICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGC 323
Score = 34.7 bits (76), Expect = 1.2
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 18 SESRTCTSSEFRCKTGRCI-PLSWKCDNEKDCSDSSDEDPTVCT 60
++S C + F+C C + KCD DC D SDE+ C+
Sbjct: 283 TQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCS 326
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 73.7 bits (173), Expect = 2e-12
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 19/171 (11%)
Query: 272 TCRL-DQFQCKDHSC------IPGALYCNGVKDCPDGSDEYNCTRQKTICDKR--TEFDC 322
TCR+ D +DH+C +PG+ C D C + E +C
Sbjct: 35 TCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHEC 94
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGENE-CEKNNGGCSQRCVDTPIGYYCDCEKG 381
S +C H DE C + + C +N GC CV+T Y C C KG
Sbjct: 95 VNA---DGSYLCQCHEGFALNPDEKT--CTKIDYCASSNHGCQHECVNTDDSYSCHCLKG 149
Query: 382 YKL-IDNRTCEDIDECA--DPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
+ L D +TC I+ CA PG C C+N + ++ C CH GY DP +T
Sbjct: 150 FTLNPDKKTCRRINYCALNKPG-CEHECVNMEESYYCRCHRGYTLDPNGKT 199
Score = 72.9 bits (171), Expect = 4e-12
Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA-DPGSCSQICINEKGTF 413
C C+ C++ P Y C C++GY L D TC D CA + +C Q+C+N G+F
Sbjct: 1 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF 60
Query: 414 KCECHTGYARDPRDRTRCKATEGHPSLLFARKHDIRKISLDH----HEMVAIVNDTKSAT 469
C+C++GYA D RC A + S +H+ + HE A+ D K+ T
Sbjct: 61 VCQCYSGYAL-AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCT 119
Query: 470 ALDY 473
+DY
Sbjct: 120 KIDY 123
Score = 70.1 bits (164), Expect = 3e-11
Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPG-SCSQICINEKG 411
N C N GC CV+ YYC C +GY L N +TC +D CA C Q+C+N +
Sbjct: 163 NYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTED 222
Query: 412 TFKCECHTGY 421
+F C+C G+
Sbjct: 223 SFVCQCSEGF 232
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPG-SCSQICINEKGTF 413
C+ + GC CV++ Y C+C +G++L D + C D C C IC+N ++
Sbjct: 329 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSY 388
Query: 414 KCECHTGYARDPRDRTRC-KATEGHPSLLF 442
C+C G+ D RC K TEG L+F
Sbjct: 389 ICKCSEGFVL-AEDGRRCKKCTEGPIDLVF 417
Score = 58.0 bits (134), Expect = 1e-07
Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 21/177 (11%)
Query: 269 GNVTCRLDQFQCKDHSCIPGALYCNG--VKDCPDG----SDEYNCTRQK--TICDKRTEF 320
G R+D +DH C L V C +G D C+R + D E+
Sbjct: 197 GKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY 256
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDEPRD--RCGE-NECEKNNGGCSQRCVDTPIGYYCD 377
C + + S C CP D C + + C + GC CV + + C
Sbjct: 257 SC---VNMDRSFACQ----CPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQ 309
Query: 378 CEKGYKL-IDNRTCEDIDEC-ADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
C +GY L D +TC D C A C IC+N ++ CEC G+ R D RC+
Sbjct: 310 CFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGF-RLAEDGKRCR 365
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 218
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 219 NIPGDFECECPEGY 232
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 121 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 178
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 239 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 154 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 211
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 212 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 271
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 272 GFKLAQDQKSCEVVSVC 288
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 218
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 219 NIPGDFECECPEGY 232
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 121 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 178
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQR-CVDTPIGYYCDCEKGYKL-IDN 387
H C N +D +EC C C + P + C+C +GY+ + +
Sbjct: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G + C C
Sbjct: 239 KSCEDIDECSE-NMCAQLCVNYPGGYTCYC 267
Score = 50.4 bits (115), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 154 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 211
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P GY YCD +K
Sbjct: 212 CGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKK 271
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 272 GFKLAQDQKSCEVVSVC 288
>AK131211-1|BAD18401.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ16088 fis, clone NT2RP7008435, weakly similar
to EPITHIN (EC 3.4.21.-). ).
Length = 572
Score = 73.7 bits (173), Expect = 2e-12
Identities = 45/131 (34%), Positives = 57/131 (43%), Gaps = 13/131 (9%)
Query: 17 FSESRTCTSSEFRCKTGRCIPLSWKCDNEKDCSDSSDEDPTVCTATKMVCQEYRFECLSD 76
++ S+ C FRC +G C+P + +CD DC D SDE C + + C F
Sbjct: 207 YNISQPCPVGSFRCSSGLCVPQAQRCDGVNDCFDESDE--LFCVSPQPACNTSSFR--QH 262
Query: 77 GLCIPRSWRCDATADCPDGSDEHQC-EVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSD 135
G I CD DC +G DE C + C F C G CD DC D
Sbjct: 263 GPLI-----CDGFRDCENGRDEQNCTQSIPCNNRTFKC-GNDICFRKQNAKCDGTVDCPD 316
Query: 136 GSDEKACNETC 146
GSDE+ C TC
Sbjct: 317 GSDEEGC--TC 325
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/123 (30%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 187 PQSHFSCTDGQCISAWWHCDGDVDCADGSDEVGCVSTPKVRSPCISTEFECNDRITCVHR 246
P F C+ G C+ CDG DC D SDE+ CVS + C ++ F + + C
Sbjct: 214 PVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSP---QPACNTSSFRQHGPLIC--- 267
Query: 247 AWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIPGA-LYCNGVKDCPDGSDEY 305
+ C ++ C F+C + C C+G DCPDGSDE
Sbjct: 268 ------DGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEE 321
Query: 306 NCT 308
CT
Sbjct: 322 GCT 324
Score = 59.3 bits (137), Expect = 5e-08
Identities = 29/68 (42%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 288 GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV-CDKHVDCPNFEDE 346
G L C+G +DC +G DE NCT Q C+ RT F CG +C CD VDCP+ DE
Sbjct: 263 GPLICDGFRDCENGRDEQNCT-QSIPCNNRT-FKCGNDICFRKQNAKCDGTVDCPDGSDE 320
Query: 347 PRDRCGEN 354
C +
Sbjct: 321 EGCTCSRS 328
Score = 50.0 bits (114), Expect = 3e-05
Identities = 37/113 (32%), Positives = 47/113 (41%), Gaps = 20/113 (17%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSK 332
C + F+C C+P A C+GV DC D SDE C + C+ + G PL
Sbjct: 213 CPVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSPQPACNTSSFRQHG-----PL-- 265
Query: 333 VCDKHVDCPNFEDEPR-----------DRCGENEC-EKNNGGCSQRCVDTPIG 373
+CD DC N DE +CG + C K N C VD P G
Sbjct: 266 ICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKC-DGTVDCPDG 317
Score = 46.4 bits (105), Expect = 4e-04
Identities = 37/119 (31%), Positives = 41/119 (34%), Gaps = 8/119 (6%)
Query: 104 EACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNGKCIQMR- 162
+ C F C G CVP CD DC D SDE C S + C Q
Sbjct: 211 QPCPVGSFRCSS--GLCVPQAQRCDGVNDCFDESDELFCV----SPQPACNTSSFRQHGP 264
Query: 163 WVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAW-WHCDGDVDCADGSDEVGC 220
+ E C F C + C CDG VDC DGSDE GC
Sbjct: 265 LICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGC 323
Score = 34.7 bits (76), Expect = 1.2
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 18 SESRTCTSSEFRCKTGRCI-PLSWKCDNEKDCSDSSDEDPTVCT 60
++S C + F+C C + KCD DC D SDE+ C+
Sbjct: 283 TQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCS 326
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
Score = 58.4 bits (135), Expect = 9e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGGFRCLAFECPENYRR 562
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
Score = 58.4 bits (135), Expect = 9e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGGFRCLAFECPENYRR 562
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 62.1 bits (144), Expect = 7e-09
Identities = 37/94 (39%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYARDPRDRTRCKATEGH 437
N +G F+C EC Y R TRC+ H
Sbjct: 543 FNIQGAFRCLAFECPENYRRSA--ATRCERLPCH 574
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 61.3 bits (142), Expect = 1e-08
Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYARDPRDRTRCKATEGHPS 439
N +G F+C EC Y R + K + P+
Sbjct: 543 FNIQGAFRCLAFECPENYRRSAATQKSKKGRQNTPA 578
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 59.3 bits (137), Expect = 5e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGAFRCLAFECPENYRR 562
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 133 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 192
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 193 NILGDFECECPEGY 206
Score = 63.3 bits (147), Expect = 3e-09
Identities = 45/150 (30%), Positives = 67/150 (44%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 95 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 152
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIG-YYCDCEKGYKL-IDN 387
H C N +D +EC C +G + C+C +GY+ + +
Sbjct: 153 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKS 212
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G C C
Sbjct: 213 KSCEDIDECSE-NMCAQLCVNYPGGHTCYC 241
Score = 48.4 bits (110), Expect = 9e-05
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 128 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 185
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P G+ YCD +K
Sbjct: 186 CGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGHTCYCDGKK 245
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 246 GFKLAQDQKSCEVVSVC 262
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 59.3 bits (137), Expect = 5e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGAFRCLAFECPENYRR 562
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 73.3 bits (172), Expect = 3e-12
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 6/74 (8%)
Query: 354 NECEKN---NGGCSQRCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECA-DPGSC-SQICI 407
NEC+ NGGCSQ C +TP Y+C C+ G+ ++ N + C+D+DEC+ P C + +C
Sbjct: 133 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCK 192
Query: 408 NEKGTFKCECHTGY 421
N G F+CEC GY
Sbjct: 193 NILGDFECECPEGY 206
Score = 63.3 bits (147), Expect = 3e-09
Identities = 45/150 (30%), Positives = 67/150 (44%), Gaps = 20/150 (13%)
Query: 285 CIPGALYCN--GVKDCPDGSDEYNCTRQKTICDKRTEFD---CGGGMCIP--LSKVCDK- 336
C P L CN G C DG + CT + ++ EFD C I S++CD
Sbjct: 95 CSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT 152
Query: 337 ----HVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIG-YYCDCEKGYKL-IDN 387
H C N +D +EC C +G + C+C +GY+ + +
Sbjct: 153 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKS 212
Query: 388 RTCEDIDECADPGSCSQICINEKGTFKCEC 417
++CEDIDEC++ C+Q+C+N G C C
Sbjct: 213 KSCEDIDECSE-NMCAQLCVNYPGGHTCYC 241
Score = 48.4 bits (110), Expect = 9e-05
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 273 CRLDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF----DCGGGMCI 328
C D +CKD S I G C+ + D GS +C + + + +C I
Sbjct: 128 CEFDINECKDPSNINGG--CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI 185
Query: 329 PLSKVC-----DKHVDCPN-FEDEPRDRCGENECEKNNGGCSQRCVDTPIGY--YCDCEK 380
+ VC D +CP + + + E+ E + C+Q CV+ P G+ YCD +K
Sbjct: 186 CGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGHTCYCDGKK 245
Query: 381 GYKLI-DNRTCEDIDEC 396
G+KL D ++CE + C
Sbjct: 246 GFKLAQDQKSCEVVSVC 262
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 68.9 bits (161), Expect = 6e-11
Identities = 36/78 (46%), Positives = 45/78 (57%), Gaps = 8/78 (10%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDP 425
G+F+C C +GY P
Sbjct: 501 IPGSFQCSCPSSGYRLAP 518
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
Score = 58.8 bits (136), Expect = 7e-08
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDNRT-CEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N + C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYARDPRDRTRCKATEGH 437
N +G F+C EC Y R TRC+ H
Sbjct: 543 FNIQGGFRCLAFECPENYRRSA--ATRCERLPCH 574
>AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein.
Length = 622
Score = 73.3 bits (172), Expect = 3e-12
Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
Query: 351 CGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICIN 408
CG+++C + GC +CV+ ++C C GYKL DN++C ID CA+ C C+N
Sbjct: 214 CGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVN 273
Query: 409 EKGTFKCECHTGYARDPRDRTRCKATE 435
G++ C C G+ +D+ C+A +
Sbjct: 274 SPGSYFCHCQVGFVLQ-QDQRSCRAID 299
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC--ADPGSCSQICINEKGT 412
C N C CV TP G C C +G+ L D R+C+ D C D G C C++E +
Sbjct: 301 CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHG-CEFQCVSEGLS 359
Query: 413 FKCECHTG--YARDPRDRTRCKATEGHPSLL 441
++C C G D + RC+ EGH L+
Sbjct: 360 YRCLCPEGRQLQADGKSCNRCR--EGHVDLV 388
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
Score = 58.4 bits (135), Expect = 9e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGGFRCLAFECPENYRR 562
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 258 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 315
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 316 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 374
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 375 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 415
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 378 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 435
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 436 IPGSFQCSCPSSGYRLAPNGR 456
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 120 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 171
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 172 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 227
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 228 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 287
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 288 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 326
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 103 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 161
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 162 CRLGESCINTVGSFRCQRDSSCGTGY 187
Score = 58.4 bits (135), Expect = 9e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 418 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 477
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 478 FNIQGGFRCLAFECPENYRR 497
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 193 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 250
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 251 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 309
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 310 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 350
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 313 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 370
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 371 IPGSFQCSCPSSGYRLAPNGR 391
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 55 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 106
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 107 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 162
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 163 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 222
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 223 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 261
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/94 (39%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 353 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 412
Query: 407 INEKGTFKC---ECHTGYARDPRDRTRCKATEGH 437
N +G F+C EC Y R TRC+ H
Sbjct: 413 FNIQGGFRCLAFECPENYRRSA--ATRCERLPCH 444
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 38 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 96
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 97 CRLGESCINTVGSFRCQRDSSCGTGY 122
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 283 HSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEF-----DCGGG-MCI--PLSK 332
H+CI G+ C K+ P+ Y+ + T C E CG G C+ P S
Sbjct: 323 HTCINTEGSYTCQ--KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSF 380
Query: 333 VCDKHVDCPNFEDEPRDRCGENECEKNNGG-CSQRCVDTPIGYYCDCEKGYKL-IDNRTC 390
C+ F+ R NEC++ G C +C +T Y C C G++L +D R+C
Sbjct: 381 RCECKTGY-YFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 391 EDIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRTRCK 432
EDI+EC+ CSQ C N G+++C C GY D C+
Sbjct: 440 EDINECSS-SPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Score = 70.5 bits (165), Expect = 2e-11
Identities = 37/81 (45%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS---CSQICIN 408
NEC ++ CSQ C + Y C C +GY+L +D TCEDIDECA P CS CIN
Sbjct: 443 NEC--SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCIN 500
Query: 409 EKGTFKCEC-HTGYARDPRDR 428
G+F+C C +GY P R
Sbjct: 501 IPGSFQCSCPSSGYRLAPNGR 521
Score = 62.5 bits (145), Expect = 5e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 35/219 (15%)
Query: 229 PCISTEFECNDRITCVHRAWVXXXXXXXXXXXXEALELCRGNVTCRLDQFQCKDHSCIP- 287
PC + D + C +V + E G+ +CRL + SCI
Sbjct: 185 PCKQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGE------SCINT 236
Query: 288 -GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL--------SKVCDKHV 338
G+ C C G Y T + C E + G C+P S C +
Sbjct: 237 VGSFRCQRDSSCGTG---YELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 339 DCPN-FEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYC-----DCEKGYKLIDNRT 389
C + F + C + NEC + C C++T Y C +C +GY L + T
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 390 -CEDIDECADPGS-CSQ--ICINEKGTFKCECHTGYARD 424
C D+DECA P C + C+N G+F+CEC TGY D
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Score = 59.3 bits (137), Expect = 5e-08
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
Query: 354 NECEKNNGG--CSQRCVDTPIGYYCDC-EKGYKLIDN-RTCEDIDECADP-GSCS--QIC 406
+EC GG CS RC++ P + C C GY+L N R C+DIDEC +CS + C
Sbjct: 483 DECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETC 542
Query: 407 INEKGTFKC---ECHTGYAR 423
N +G F+C EC Y R
Sbjct: 543 FNIQGAFRCLAFECPENYRR 562
Score = 58.8 bits (136), Expect = 7e-08
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 9/86 (10%)
Query: 344 EDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDEC-ADPGS 401
E+E D + C + G C Q+C DT C C GY+L+ D +CED++EC S
Sbjct: 168 EEEQEDPYLNDRC-RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 402 C--SQICINEKGTFKCE----CHTGY 421
C + CIN G+F+C+ C TGY
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGY 252
>AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding protein
1 variant protein.
Length = 620
Score = 72.9 bits (171), Expect = 4e-12
Identities = 32/79 (40%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 263 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 322
Query: 422 ARDPRDRTRCKATEGHPSL 440
RD C P++
Sbjct: 323 ELH-RDGFSCSGESSIPAV 340
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 422 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 481
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 482 GGYRCVDTNRCVEPYIQVSENRCLCPAS 509
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 71.3 bits (167), Expect = 1e-11
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGS--CSQICINE 409
+EC C+Q C +T ++C CE+GY L D C+D+DEC PG C +C N
Sbjct: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
Query: 410 KGTFKCECHTGYARDP 425
+G+F C C G+ P
Sbjct: 447 QGSFHCGCLPGWVLAP 462
Score = 69.7 bits (163), Expect = 4e-11
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 323 GGGMCIPLSKVCDKHVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE 379
GG C+ + CP + D +EC+ + C+Q CV+TP G+ C+C
Sbjct: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECW 370
Query: 380 KGYKL--IDNRTCEDIDECADPGS-CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
GY+ C+D+DECA S C+Q C N G+F C C GY D T+C+
Sbjct: 371 VGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNR-TCEDIDEC-ADPGSCSQICI-NEKG 411
C NNGGC Q C + G + C C G++L+D+ TC + C + P C+ G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 412 -TFKCECHTGYARD 424
+ C C GY D
Sbjct: 324 KNYTCRCPQGYQLD 337
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 71.3 bits (167), Expect = 1e-11
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGS--CSQICINE 409
+EC C+Q C +T ++C CE+GY L D C+D+DEC PG C +C N
Sbjct: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
Query: 410 KGTFKCECHTGYARDP 425
+G+F C C G+ P
Sbjct: 447 QGSFHCGCLPGWVLAP 462
Score = 69.7 bits (163), Expect = 4e-11
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 323 GGGMCIPLSKVCDKHVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE 379
GG C+ + CP + D +EC+ + C+Q CV+TP G+ C+C
Sbjct: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECW 370
Query: 380 KGYKL--IDNRTCEDIDECADPGS-CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
GY+ C+D+DECA S C+Q C N G+F C C GY D T+C+
Sbjct: 371 VGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNR-TCEDIDEC-ADPGSCSQICI-NEKG 411
C NNGGC Q C + G + C C G++L+D+ TC + C + P C+ G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 412 -TFKCECHTGYARD 424
+ C C GY D
Sbjct: 324 KNYTCRCPQGYQLD 337
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 71.3 bits (167), Expect = 1e-11
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGS--CSQICINE 409
+EC C+Q C +T ++C CE+GY L D C+D+DEC PG C +C N
Sbjct: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
Query: 410 KGTFKCECHTGYARDP 425
+G+F C C G+ P
Sbjct: 447 QGSFHCGCLPGWVLAP 462
Score = 69.7 bits (163), Expect = 4e-11
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 323 GGGMCIPLSKVCDKHVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE 379
GG C+ + CP + D +EC+ + C+Q CV+TP G+ C+C
Sbjct: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECW 370
Query: 380 KGYKL--IDNRTCEDIDECADPGS-CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
GY+ C+D+DECA S C+Q C N G+F C C GY D T+C+
Sbjct: 371 VGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNR-TCEDIDEC-ADPGSCSQICI-NEKG 411
C NNGGC Q C + G + C C G++L+D+ TC + C + P C+ G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 412 -TFKCECHTGYARD 424
+ C C GY D
Sbjct: 324 KNYTCRCPQGYQLD 337
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 71.3 bits (167), Expect = 1e-11
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGS--CSQICINE 409
+EC C+Q C +T ++C CE+GY L D C+D+DEC PG C +C N
Sbjct: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
Query: 410 KGTFKCECHTGYARDP 425
+G+F C C G+ P
Sbjct: 447 QGSFHCGCLPGWVLAP 462
Score = 69.3 bits (162), Expect = 5e-11
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL--IDNRTCEDIDECADPGS-CSQICINEK 410
+EC+ + C+Q CV+TP G+ C+C GY+ C+D+DECA S C+Q C N
Sbjct: 347 DECQ--DSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
Query: 411 GTFKCECHTGYARDPRDRTRCK 432
G+F C C GY D T+C+
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQ 426
Score = 62.1 bits (144), Expect = 7e-09
Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 19/127 (14%)
Query: 302 SDEYNCTRQKTICDKRTEFDCGGGM----CIPLSKVCDKHVDCPNFEDEPRDRCGENECE 357
S +Y C C + F+ G G C P ++ D V C + R+ C + C
Sbjct: 259 SPKYGCNFNNGGCHQDC-FEGGDGSFLCGCRPGFRLLDDLVTCAS-----RNPCSSSPCR 312
Query: 358 KNNGGCSQRCVDTPIG--YYCDCEKGYKLIDNRT-CEDIDECADPGSCSQICINEKGTFK 414
GG + C P G Y C C +GY+L ++ C D+DEC D C+Q C+N G F+
Sbjct: 313 ---GGAT--CALGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD-SPCAQECVNTPGGFR 366
Query: 415 CECHTGY 421
CEC GY
Sbjct: 367 CECWVGY 373
Score = 44.8 bits (101), Expect = 0.001
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNR-TCEDIDEC-ADPGSCSQIC-INEKG 411
C NNGGC Q C + G + C C G++L+D+ TC + C + P C + G
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHG 323
Query: 412 -TFKCECHTGYARD 424
+ C C GY D
Sbjct: 324 KNYTCRCPQGYQLD 337
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 71.3 bits (167), Expect = 1e-11
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI--DNRTCEDIDECADPGS--CSQICINE 409
+EC C+Q C +T ++C CE+GY L D C+D+DEC PG C +C N
Sbjct: 406 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 465
Query: 410 KGTFKCECHTGYARDP 425
+G+F C C G+ P
Sbjct: 466 QGSFHCGCLPGWVLAP 481
Score = 69.7 bits (163), Expect = 4e-11
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 323 GGGMCIPLSKVCDKHVDCPN---FEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCE 379
GG C+ + CP + D +EC+ + C+Q CV+TP G+ C+C
Sbjct: 332 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECW 389
Query: 380 KGYKL--IDNRTCEDIDECADPGS-CSQICINEKGTFKCECHTGYARDPRDRTRCK 432
GY+ C+D+DECA S C+Q C N G+F C C GY D T+C+
Sbjct: 390 VGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQ 445
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 356 CEKNNGGCSQRCVDTPIG-YYCDCEKGYKLIDNR-TCEDIDEC-ADPGSCSQICI-NEKG 411
C NNGGC Q C + G + C C G++L+D+ TC + C + P C+ G
Sbjct: 283 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 342
Query: 412 -TFKCECHTGYARD 424
+ C C GY D
Sbjct: 343 KNYTCRCPQGYQLD 356
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 65.3 bits (152), Expect = 8e-10
Identities = 34/85 (40%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Query: 341 PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECA 397
P F+ P +R C + NEC+ C QRC ++ + C C +GY+L D +C DIDEC+
Sbjct: 190 PGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECS 248
Query: 398 -DPGSCSQICINEKGTFKCECHTGY 421
C C+NE G F C C GY
Sbjct: 249 YSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEK--NNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + ++ SQ C + Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 169 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 228
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 113 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 172
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 173 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 231
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 232 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 269
Score = 62.9 bits (146), Expect = 4e-09
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 10/154 (6%)
Query: 280 CKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHV 338
C+D + C+ C G C + Y C + G G P+ V + +
Sbjct: 49 CRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPVNTQPL 105
Query: 339 DCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDE 395
+E + +D C + +EC + C SQ C + P Y C C GY+ I C DIDE
Sbjct: 106 PT-GYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CVDIDE 163
Query: 396 CADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
C C C+N G+F+C+C G+ P +R+
Sbjct: 164 CRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 196
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC---ADPGSCSQICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC A S +Q C+N
Sbjct: 241 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQWSEAQTCVNFH 300
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 301 GGYRCVDTNRCVEPYIQVSENRCLCPAS 328
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 70.9 bits (166), Expect = 2e-11
Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Query: 363 CSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQICINEKGTFKCECHTGY 421
C RCV+ P + C CE G++L +NR+C D++EC C Q C N GTF C CH GY
Sbjct: 173 CQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGY 232
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/158 (28%), Positives = 67/158 (42%), Gaps = 9/158 (5%)
Query: 276 DQFQCKD-HSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
D C+D + C+ C G C + Y C + G G P+
Sbjct: 48 DSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLH---GEGPPPPVPPAQ 104
Query: 335 DKHVDCPNFEDEPRDRCGE-NECEKNNGGC--SQRCVDTPIGYYCDCEKGYKLIDNRTCE 391
+ P +E + +D C + +EC + C SQ C + P Y C C GY+ I C
Sbjct: 105 HPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPE-CV 163
Query: 392 DIDECADPGSCSQICINEKGTFKCECHTGYARDPRDRT 429
DIDEC C C+N G+F+C+C G+ P +R+
Sbjct: 164 DIDECRYR-YCQHRCVNLPGSFRCQCEPGFQLGPNNRS 200
Score = 67.3 bits (157), Expect = 2e-10
Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 13/158 (8%)
Query: 276 DQFQCKDHSCIPGALY-CNGVKDCPDGSDEYNCT---RQKTICDKRTEFD-CGGGMCIPL 330
DQ C D AL+ C +DC + Y CT + I + + D C C
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHR 176
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKL- 384
C P F+ P +R C + NEC+ C QRC ++ + C C +GY+L
Sbjct: 177 CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMG-APCEQRCFNSYGTFLCRCHQGYELH 235
Query: 385 IDNRTCEDIDECA-DPGSCSQICINEKGTFKCECHTGY 421
D +C DIDEC+ C C+NE G F C C GY
Sbjct: 236 RDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGY 273
Score = 61.7 bits (143), Expect = 9e-09
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 354 NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCS--QICINEK 410
+EC ++ C RCV+ P + C C +GY+L+ R C+DIDEC + CS Q C+N
Sbjct: 245 DECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFH 304
Query: 411 GTFKC----ECHTGYARDPRDRTRCKAT 434
G ++C C Y + +R C A+
Sbjct: 305 GGYRCVDTNRCVEPYIQVSENRCLCPAS 332
>AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein.
Length = 432
Score = 69.7 bits (163), Expect = 4e-11
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Query: 352 GENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECAD-PGSCSQICINE 409
G+++C + GC +CV+ ++C C GYKL DN++C ID CA+ C C+N
Sbjct: 25 GKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNS 84
Query: 410 KGTFKCECHTGYARDPRDRTRCKATE 435
G++ C C G+ +D+ C+A +
Sbjct: 85 PGSYFCHCQVGFVLQ-QDQRSCRAID 109
Score = 53.2 bits (122), Expect = 3e-06
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 356 CEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC--ADPGSCSQICINEKGT 412
C N C CV TP G C C +G+ L D R+C+ D C D G C C++E +
Sbjct: 111 CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHG-CEFQCVSEGLS 169
Query: 413 FKCECHTG--YARDPRDRTRCKATEGHPSLL 441
++C C G D + RC+ EGH L+
Sbjct: 170 YRCLCPEGRQLQADGKSCNRCR--EGHVDLV 198
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 69.3 bits (162), Expect = 5e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 20/161 (12%)
Query: 273 CRLDQFQCKDHSC--IPGALYCNGVKDCPDG---SDEYNCTRQKTICDKRTEFDCGGGMC 327
C+ D C+ C G+ C +CP G S + C+ C G C
Sbjct: 321 CQRDPLLCRGGVCHNTEGSYRC----ECPPGHQLSPNISACIDINECELSAHL-CPNGRC 375
Query: 328 IPLSKVCDKHVDC-PNFEDEPRDR--CGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYK 383
+ L + C P + P DR C + +EC NGGC C ++ Y C C+ G+
Sbjct: 376 VNL--IGKYQCACNPGYHSTP-DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFA 432
Query: 384 LI-DNRTCEDIDECAD-PGSC-SQICINEKGTFKCECHTGY 421
L+ D R+C DIDEC D P C C N G ++C C+ G+
Sbjct: 433 LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 473
Score = 64.5 bits (150), Expect = 1e-09
Identities = 52/169 (30%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query: 273 CRLDQFQCKDHSCI--PGALYCNGVKDCPDGSDEYNCTRQKTICD----KRTEFDCGGGM 326
CR+ C C+ PG C C +G E K D +R C GG+
Sbjct: 278 CRISPDLCGRGQCVNTPGDFECK----CDEGY-ESGFMMMKNCMDIDECQRDPLLCRGGV 332
Query: 327 CIPLSKVCDKHVDCP-NFEDEPR-DRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGY 382
C +CP + P C + NECE + C RCV+ Y C C GY
Sbjct: 333 CHNTEG--SYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 390
Query: 383 KLIDNRT-CEDIDECADP-GSCSQICINEKGTFKCECHTGYARDPRDRT 429
+R C DIDEC+ G C C N +G+++C C G+A P R+
Sbjct: 391 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 439
Score = 60.1 bits (139), Expect = 3e-08
Identities = 49/161 (30%), Positives = 66/161 (40%), Gaps = 18/161 (11%)
Query: 273 CRLDQFQCKDHSCIP--GALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPL 330
C L C + C+ G C C G Y+ T + C E G C
Sbjct: 363 CELSAHLCPNGRCVNLIGKYQCA----CNPG---YHSTPDRLFCVDIDECSIMNGGCETF 415
Query: 331 SKVCDKHVDC---PNFEDEPRDR-CGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL 384
+ +C P F P R C + +ECE N C +C + P Y C C G+
Sbjct: 416 CTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 475
Query: 385 I-DNRTCEDIDEC-ADPGSC-SQICINEKGTFKCECHTGYA 422
D +TC D++EC +P C S C N KG+F C C GY+
Sbjct: 476 SEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS 516
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 378 CEKGYKLIDNRTCEDIDEC-ADPGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
C KGY I CEDIDEC PG C +C+N +G+FKC+C +G D R
Sbjct: 100 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGR 152
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 354 NECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKL-IDNRTCEDIDEC-ADPGSCSQ-ICINE 409
NEC+ C+ +C +T + C C+ G+ L + R C DIDEC P C + C+N
Sbjct: 234 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 293
Query: 410 KGTFKCECHTGY 421
G F+C+C GY
Sbjct: 294 PGDFECKCDEGY 305
Score = 35.9 bits (79), Expect = 0.54
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 391 EDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDPRDR 428
+DI+EC P C+ C N G+FKC C +G+A D +R
Sbjct: 231 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 270
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 68.9 bits (161), Expect = 6e-11
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHT 419
G C Q C + P Y C C G+ L D R+C+D++ECA C Q C+N G+F C C
Sbjct: 175 GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDP 234
Query: 420 GYARDPRDRTRC 431
GY + D C
Sbjct: 235 GYELE-EDGVHC 245
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 10/103 (9%)
Query: 341 PNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P +E +E C + +EC + C CV+ P Y+C C GY L+ DNR+C+DI+EC
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 398 DPG-SCS--QICINEKGTFKC----ECHTGYARDPRDRTRCKA 433
+C+ Q C N +G FKC C Y R +R C A
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA 336
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 345 DEPRDRCGENECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC 402
DE +EC ++ C+ Q C++T GY C C GY L++ + C DIDEC G C
Sbjct: 120 DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDIDECR-YGYC 177
Query: 403 SQICINEKGTFKCECHTGYARDPRDRT 429
Q+C N G++ C C+ G+ + R+
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRS 204
Score = 49.2 bits (112), Expect = 5e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 378 CEKGYKLIDNRTCEDIDECA-DPGSCS--QICINEKGTFKCECHTGY 421
C GY++ ++ C D+DECA D C+ QICIN +G + C C GY
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY 159
Score = 32.7 bits (71), Expect = 5.0
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTCR----GKPG----ECVPLTWMCDDNPDCSDG 136
RCD + + H +++ C EF C+ +PG C P + DDN C D
Sbjct: 231 RCDPGYELEEDG-VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDI 289
Query: 137 SDEKACNETCRSDEFTC----GNGKCI 159
++ + N TC + TC G KCI
Sbjct: 290 NECEHRNHTCNLQQ-TCYNLQGGFKCI 315
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 68.9 bits (161), Expect = 6e-11
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHT 419
G C Q C + P Y C C G+ L D R+C+D++ECA C Q C+N G+F C C
Sbjct: 175 GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDP 234
Query: 420 GYARDPRDRTRC 431
GY + D C
Sbjct: 235 GYELE-EDGVHC 245
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 10/103 (9%)
Query: 341 PNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P +E +E C + +EC + C CV+ P Y+C C GY L+ DNR+C+DI+EC
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 398 DPG-SCS--QICINEKGTFKC----ECHTGYARDPRDRTRCKA 433
+C+ Q C N +G FKC C Y R +R C A
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA 336
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 345 DEPRDRCGENECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC 402
DE +EC ++ C+ Q C++T GY C C GY L++ + C DIDEC G C
Sbjct: 120 DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDIDECR-YGYC 177
Query: 403 SQICINEKGTFKCECHTGYARDPRDRT 429
Q+C N G++ C C+ G+ + R+
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRS 204
Score = 49.2 bits (112), Expect = 5e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 378 CEKGYKLIDNRTCEDIDECA-DPGSCS--QICINEKGTFKCECHTGY 421
C GY++ ++ C D+DECA D C+ QICIN +G + C C GY
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY 159
Score = 32.7 bits (71), Expect = 5.0
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTCR----GKPG----ECVPLTWMCDDNPDCSDG 136
RCD + + H +++ C EF C+ +PG C P + DDN C D
Sbjct: 231 RCDPGYELEEDG-VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDI 289
Query: 137 SDEKACNETCRSDEFTC----GNGKCI 159
++ + N TC + TC G KCI
Sbjct: 290 NECEHRNHTCNLQQ-TCYNLQGGFKCI 315
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 68.9 bits (161), Expect = 6e-11
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHT 419
G C Q C + P Y C C G+ L D R+C+D++ECA C Q C+N G+F C C
Sbjct: 175 GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDP 234
Query: 420 GYARDPRDRTRC 431
GY + D C
Sbjct: 235 GYELE-EDGVHC 245
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 10/103 (9%)
Query: 341 PNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P +E +E C + +EC + C CV+ P Y+C C GY L+ DNR+C+DI+EC
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 398 DPG-SCS--QICINEKGTFKC----ECHTGYARDPRDRTRCKA 433
+C+ Q C N +G FKC C Y R +R C A
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA 336
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 345 DEPRDRCGENECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC 402
DE +EC ++ C+ Q C++T GY C C GY L++ + C DIDEC G C
Sbjct: 120 DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDIDECR-YGYC 177
Query: 403 SQICINEKGTFKCECHTGYARDPRDRT 429
Q+C N G++ C C+ G+ + R+
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRS 204
Score = 49.2 bits (112), Expect = 5e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 378 CEKGYKLIDNRTCEDIDECA-DPGSCS--QICINEKGTFKCECHTGY 421
C GY++ ++ C D+DECA D C+ QICIN +G + C C GY
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY 159
Score = 32.7 bits (71), Expect = 5.0
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTCR----GKPG----ECVPLTWMCDDNPDCSDG 136
RCD + + H +++ C EF C+ +PG C P + DDN C D
Sbjct: 231 RCDPGYELEEDG-VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDI 289
Query: 137 SDEKACNETCRSDEFTC----GNGKCI 159
++ + N TC + TC G KCI
Sbjct: 290 NECEHRNHTCNLQQ-TCYNLQGGFKCI 315
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 68.9 bits (161), Expect = 6e-11
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHT 419
G C Q C + P Y C C G+ L D R+C+D++ECA C Q C+N G+F C C
Sbjct: 175 GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDP 234
Query: 420 GYARDPRDRTRC 431
GY + D C
Sbjct: 235 GYELE-EDGVHC 245
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 10/103 (9%)
Query: 341 PNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P +E +E C + +EC + C CV+ P Y+C C GY L+ DNR+C+DI+EC
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 398 DPG-SCS--QICINEKGTFKC----ECHTGYARDPRDRTRCKA 433
+C+ Q C N +G FKC C Y R +R C A
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA 336
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 345 DEPRDRCGENECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC 402
DE +EC ++ C+ Q C++T GY C C GY L++ + C DIDEC G C
Sbjct: 120 DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQ-CLDIDECR-YGYC 177
Query: 403 SQICINEKGTFKCECHTGYARDPRDRT 429
Q+C N G++ C C+ G+ + R+
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRS 204
Score = 49.2 bits (112), Expect = 5e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 378 CEKGYKLIDNRTCEDIDECA-DPGSCS--QICINEKGTFKCECHTGY 421
C GY++ ++ C D+DECA D C+ QICIN +G + C C GY
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGY 159
Score = 32.7 bits (71), Expect = 5.0
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTCR----GKPG----ECVPLTWMCDDNPDCSDG 136
RCD + + H +++ C EF C+ +PG C P + DDN C D
Sbjct: 231 RCDPGYELEEDG-VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDI 289
Query: 137 SDEKACNETCRSDEFTC----GNGKCI 159
++ + N TC + TC G KCI
Sbjct: 290 NECEHRNHTCNLQQ-TCYNLQGGFKCI 315
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 68.9 bits (161), Expect = 6e-11
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 361 GGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECADPGSCSQICINEKGTFKCECHT 419
G C Q C + P Y C C G+ L D R+C+D++ECA C Q C+N G+F C C
Sbjct: 175 GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDP 234
Query: 420 GYARDPRDRTRC 431
GY + D C
Sbjct: 235 GYELE-EDGVHC 245
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 10/103 (9%)
Query: 341 PNFE-DEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCEDIDECA 397
P +E +E C + +EC + C CV+ P Y+C C GY L+ DNR+C+DI+EC
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 398 DPG-SCS--QICINEKGTFKC----ECHTGYARDPRDRTRCKA 433
+C+ Q C N +G FKC C Y R +R C A
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA 336
Score = 62.1 bits (144), Expect = 7e-09
Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 345 DEPRDRCGENECEKNNGGCS--QRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSC 402
DE +EC ++ C+ Q C++ GY C C GY L++ + C DIDEC G C
Sbjct: 120 DESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQ-CLDIDECR-YGYC 177
Query: 403 SQICINEKGTFKCECHTGYARDPRDRT 429
Q+C N G++ C C+ G+ + R+
Sbjct: 178 QQLCANVPGSYSCTCNPGFTLNEDGRS 204
Score = 50.4 bits (115), Expect = 2e-05
Identities = 22/47 (46%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Query: 378 CEKGYKLIDNRTCEDIDECA-DPGSCS--QICINEKGTFKCECHTGY 421
C GY++ ++ C D+DECA D C+ QICIN KG + C C GY
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGY 159
Score = 32.7 bits (71), Expect = 5.0
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 85 RCDATADCPDGSDEHQCEVEACGPEEFTCR----GKPG----ECVPLTWMCDDNPDCSDG 136
RCD + + H +++ C EF C+ +PG C P + DDN C D
Sbjct: 231 RCDPGYELEEDG-VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDI 289
Query: 137 SDEKACNETCRSDEFTC----GNGKCI 159
++ + N TC + TC G KCI
Sbjct: 290 NECEHRNHTCNLQQ-TCYNLQGGFKCI 315
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 68.1 bits (159), Expect = 1e-10
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 18/162 (11%)
Query: 273 CRLDQFQCKDHSCIPG----ALYCN-GVKDCPDGS---DEYNCTRQKTICDKRTEFDCGG 324
CRL+Q C C+PG + +CN G + P D C + + + GG
Sbjct: 65 CRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG 124
Query: 325 GMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNN-GGCSQRCVDTPIGYYCDCEKGYK 383
++ HV R NEC K + G C++ P Y C+C GY+
Sbjct: 125 SYNCHCNRGYRLHVGAGG-----RSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 179
Query: 384 LIDNR--TCEDIDECADPGSCSQ-ICINEKGTFKC-ECHTGY 421
L +R CEDIDEC DP SC C N+ G+FKC C GY
Sbjct: 180 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 221
Score = 63.7 bits (148), Expect = 2e-09
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Query: 336 KHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCED 392
K + C P + + C + NEC + + C + P + C C +GY D R+C D
Sbjct: 213 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 272
Query: 393 IDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+DEC C IC N G+F+C+C +GY RDR+ C+
Sbjct: 273 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLS-RDRSHCE 312
Score = 60.9 bits (141), Expect = 2e-08
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 20/150 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF-EDEP--- 347
C CPDG E K I + GGG C +++ + P + E+ P
Sbjct: 194 CRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSF 253
Query: 348 RDRCGE--------------NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CED 392
R C + +ECE + + C +TP + C C GY L +R+ CED
Sbjct: 254 RCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 313
Query: 393 IDECADPGSC-SQICINEKGTFKCECHTGY 421
IDEC P +C CIN G+++C C G+
Sbjct: 314 IDECDFPAACIGGDCINTNGSYRCLCPQGH 343
Score = 58.8 bits (136), Expect = 7e-08
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 348 RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSC--S 403
R C + +EC+ C++T Y C C +G++L+ R C+DIDEC+ DP C
Sbjct: 308 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 367
Query: 404 QICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C N +G++ C C G+ +D+ C+ E
Sbjct: 368 GACKNLQGSYVCVCDEGFT-PTQDQHGCEEVE 398
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECADPGS---- 401
PRD E S RCV P G C+C G++L +R C DIDEC +
Sbjct: 648 PRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLL 707
Query: 402 C-SQICINEKGTFKCECHTGYAR 423
C S+ C+N G+F+C C G+AR
Sbjct: 708 CKSERCVNTSGSFRCVCKAGFAR 730
Score = 56.0 bits (129), Expect = 5e-07
Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 31/177 (17%)
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
+D +C+ C PG G+ C + YNC + R GG C+ L++
Sbjct: 102 VDVNECEAEPCGPG----RGI--CMNTGGSYNCHCNRGY---RLHVGAGGRSCVDLNECA 152
Query: 335 DKHVD-----CPNFEDEPRDRCGE---------------NECEKNNGGCSQRCVDTPIGY 374
H+ C NF + C +EC + +C + P +
Sbjct: 153 KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSF 212
Query: 375 YC-DCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
C C+ GY+ C D++ECA+ CS C N G+F+C C GYA P R+
Sbjct: 213 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRS 269
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSC-SQICINEKGTFKCECHTGYAR 423
+CV+T GY C C++G+ N C D+DEC D +C + +C N +G ++C C
Sbjct: 496 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEY 555
Query: 424 DPRDRTRCKATE 435
P R +C + E
Sbjct: 556 SPAQR-QCLSPE 566
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 68.1 bits (159), Expect = 1e-10
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 18/162 (11%)
Query: 273 CRLDQFQCKDHSCIPG----ALYCN-GVKDCPDGS---DEYNCTRQKTICDKRTEFDCGG 324
CRL+Q C C+PG + +CN G + P D C + + + GG
Sbjct: 657 CRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG 716
Query: 325 GMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNN-GGCSQRCVDTPIGYYCDCEKGYK 383
++ HV R NEC K + G C++ P Y C+C GY+
Sbjct: 717 SYNCHCNRGYRLHVGAGG-----RSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 771
Query: 384 LIDNR--TCEDIDECADPGSCSQ-ICINEKGTFKC-ECHTGY 421
L +R CEDIDEC DP SC C N+ G+FKC C GY
Sbjct: 772 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 813
Score = 63.7 bits (148), Expect = 2e-09
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Query: 336 KHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCED 392
K + C P + + C + NEC + + C + P + C C +GY D R+C D
Sbjct: 805 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 864
Query: 393 IDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+DEC C IC N G+F+C+C +GY RDR+ C+
Sbjct: 865 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLS-RDRSHCE 904
Score = 60.9 bits (141), Expect = 2e-08
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 20/150 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF-EDEP--- 347
C CPDG E K I + GGG C +++ + P + E+ P
Sbjct: 786 CRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSF 845
Query: 348 RDRCGE--------------NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CED 392
R C + +ECE + + C +TP + C C GY L +R+ CED
Sbjct: 846 RCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 905
Query: 393 IDECADPGSC-SQICINEKGTFKCECHTGY 421
IDEC P +C CIN G+++C C G+
Sbjct: 906 IDECDFPAACIGGDCINTNGSYRCLCPQGH 935
Score = 59.7 bits (138), Expect = 4e-08
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 377 DCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKA 433
DC +GYK +++ C+DI+ECA PG C C+N G+++C C G++ P RT+C A
Sbjct: 419 DCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGP-SRTQCIA 475
Score = 58.8 bits (136), Expect = 7e-08
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 348 RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSC--S 403
R C + +EC+ C++T Y C C +G++L+ R C+DIDEC+ DP C
Sbjct: 900 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 959
Query: 404 QICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C N +G++ C C G+ +D+ C+ E
Sbjct: 960 GACKNLQGSYVCVCDEGFT-PTQDQHGCEEVE 990
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECADPGS---- 401
PRD E S RCV P G C+C G++L +R C DIDEC +
Sbjct: 1287 PRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLL 1346
Query: 402 C-SQICINEKGTFKCECHTGYAR 423
C S+ C+N G+F+C C G+AR
Sbjct: 1347 CKSERCVNTSGSFRCVCKAGFAR 1369
Score = 56.0 bits (129), Expect = 5e-07
Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 31/177 (17%)
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
+D +C+ C PG G+ C + YNC + R GG C+ L++
Sbjct: 694 VDVNECEAEPCGPG----RGI--CMNTGGSYNCHCNRGY---RLHVGAGGRSCVDLNECA 744
Query: 335 DKHVD-----CPNFEDEPRDRCGE---------------NECEKNNGGCSQRCVDTPIGY 374
H+ C NF + C +EC + +C + P +
Sbjct: 745 KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSF 804
Query: 375 YC-DCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
C C+ GY+ C D++ECA+ CS C N G+F+C C GYA P R+
Sbjct: 805 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRS 861
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSC-SQICINEKGTFKCECHTGYAR 423
+CV+T GY C C++G+ N C D+DEC D +C + +C N +G ++C C
Sbjct: 1088 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEY 1147
Query: 424 DPRDRTRCKATE 435
P R +C + E
Sbjct: 1148 SPAQR-QCLSPE 1158
Score = 48.8 bits (111), Expect = 7e-05
Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 338 VDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA 397
VD DE C CE GG RC TP Y ++ + D+DEC
Sbjct: 1114 VDVDECLDE--SNCRNGVCENTRGG--YRCACTPPAEYSPAQRQCLSPEEM---DVDECQ 1166
Query: 398 DPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKATE 435
DP +C C+N G+++CEC + P R C+ E
Sbjct: 1167 DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRD-CQLPE 1204
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 68.1 bits (159), Expect = 1e-10
Identities = 53/162 (32%), Positives = 71/162 (43%), Gaps = 18/162 (11%)
Query: 273 CRLDQFQCKDHSCIPG----ALYCN-GVKDCPDGS---DEYNCTRQKTICDKRTEFDCGG 324
CRL+Q C C+PG + +CN G + P D C + + + GG
Sbjct: 578 CRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG 637
Query: 325 GMCIPLSKVCDKHVDCPNFEDEPRDRCGENECEKNN-GGCSQRCVDTPIGYYCDCEKGYK 383
++ HV R NEC K + G C++ P Y C+C GY+
Sbjct: 638 SYNCHCNRGYRLHVGAGG-----RSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 384 LIDNR--TCEDIDECADPGSCSQ-ICINEKGTFKC-ECHTGY 421
L +R CEDIDEC DP SC C N+ G+FKC C GY
Sbjct: 693 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 734
Score = 63.7 bits (148), Expect = 2e-09
Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Query: 336 KHVDC-PNFEDEPRDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLI-DNRTCED 392
K + C P + + C + NEC + + C + P + C C +GY D R+C D
Sbjct: 726 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 393 IDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCK 432
+DEC C IC N G+F+C+C +GY RDR+ C+
Sbjct: 786 VDECEAGDVCDNGICSNTPGSFQCQCLSGYHLS-RDRSHCE 825
Score = 60.9 bits (141), Expect = 2e-08
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 20/150 (13%)
Query: 292 CNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDCPNF-EDEP--- 347
C CPDG E K I + GGG C +++ + P + E+ P
Sbjct: 707 CRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSF 766
Query: 348 RDRCGE--------------NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CED 392
R C + +ECE + + C +TP + C C GY L +R+ CED
Sbjct: 767 RCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 826
Query: 393 IDECADPGSC-SQICINEKGTFKCECHTGY 421
IDEC P +C CIN G+++C C G+
Sbjct: 827 IDECDFPAACIGGDCINTNGSYRCLCPQGH 856
Score = 59.7 bits (138), Expect = 4e-08
Identities = 25/58 (43%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 377 DCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRTRCKA 433
DC +GYK +++ C+DI+ECA PG C C+N G+++C C G++ P RT+C A
Sbjct: 340 DCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGP-SRTQCIA 396
Score = 58.8 bits (136), Expect = 7e-08
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 348 RDRCGE-NECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECA-DPGSC--S 403
R C + +EC+ C++T Y C C +G++L+ R C+DIDEC+ DP C
Sbjct: 821 RSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPH 880
Query: 404 QICINEKGTFKCECHTGYARDPRDRTRCKATE 435
C N +G++ C C G+ +D+ C+ E
Sbjct: 881 GACKNLQGSYVCVCDEGFT-PTQDQHGCEEVE 911
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 347 PRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECADPGS---- 401
PRD E S RCV P G C+C G++L +R C DIDEC +
Sbjct: 1161 PRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLL 1220
Query: 402 C-SQICINEKGTFKCECHTGYAR 423
C S+ C+N G+F+C C G+AR
Sbjct: 1221 CKSERCVNTSGSFRCVCKAGFAR 1243
Score = 56.0 bits (129), Expect = 5e-07
Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 31/177 (17%)
Query: 275 LDQFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGGGMCIPLSKVC 334
+D +C+ C PG G+ C + YNC + R GG C+ L++
Sbjct: 615 VDVNECEAEPCGPG----RGI--CMNTGGSYNCHCNRGY---RLHVGAGGRSCVDLNECA 665
Query: 335 DKHVD-----CPNFEDEPRDRCGE---------------NECEKNNGGCSQRCVDTPIGY 374
H+ C NF + C +EC + +C + P +
Sbjct: 666 KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSF 725
Query: 375 YC-DCEKGYKLIDNRTCEDIDECADPGSCSQ-ICINEKGTFKCECHTGYARDPRDRT 429
C C+ GY+ C D++ECA+ CS C N G+F+C C GYA P R+
Sbjct: 726 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRS 782
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 366 RCVDTPIGYYCDCEKGYKLIDN-RTCEDIDECADPGSC-SQICINEKGTFKCECHTGYAR 423
+CV+T GY C C++G+ N C D+DEC D +C + +C N +G ++C C
Sbjct: 1009 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEY 1068
Query: 424 DPRDRTRCKATE 435
P R +C + E
Sbjct: 1069 SPAQR-QCLSPE 1079
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 67.7 bits (158), Expect = 1e-10
Identities = 89/353 (25%), Positives = 125/353 (35%), Gaps = 42/353 (11%)
Query: 97 DEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG 156
D C C CR C PL D P G K C C G
Sbjct: 288 DGDHCRNCTCKSGAVECRRM--SCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEG 345
Query: 157 KCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG-- 214
+ I + E+ CP C + H + QC C G CA+G
Sbjct: 346 QRILTKSCRECRGGVLVKITEM-CPPLNCSEKDHI-LPENQCCRV---CRGHNFCAEGPK 400
Query: 215 -SDEVGCVS-----TPKVRSPCISTEFE---CNDRITCVHRA-WVXXXXXXXXXXXXEAL 264
+ C + T + +S IS + + C D C + +
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 265 ELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK------TICDKR 317
+ G + R+D F C +H C G C+ C + ++CT + TIC
Sbjct: 461 DCVPGYI--RVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAF 518
Query: 318 TEFDCG-GGMCIPLSK-VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
E C GG C+ +K VC + E + D C E E +N RCV+ P Y+
Sbjct: 519 CEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDI-DECSEGIIECHN---HSRCVNLPGWYH 574
Query: 376 CDCEKGYK-----LIDNRTCEDIDECA-DPGSC--SQICINEKGTFKCECHTG 420
C+C G+ + +C DIDECA +C CIN G F C C +G
Sbjct: 575 CECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC-----GENEC-EKNNGGCSQRCVDTPIG 373
+C GG+ + ++++C ++C + P ++C G N C E G + C +
Sbjct: 355 ECRGGVLVKITEMCPP-LNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTK 413
Query: 374 YYCDCEKGYKLI--DNRTCEDIDECADPGS---CSQICINEKGTFKCECHTGYAR 423
C+C+ GY + D+ CEDIDECA + +C+N G ++C+C GY R
Sbjct: 414 ATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIR 468
Score = 46.0 bits (104), Expect = 5e-04
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 367 CVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICINEKGTFKCECHTGY 421
CV+ P Y CDC GY +D+ +C + DEC + +C + IC N C C GY
Sbjct: 451 CVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 67.7 bits (158), Expect = 1e-10
Identities = 89/353 (25%), Positives = 125/353 (35%), Gaps = 42/353 (11%)
Query: 97 DEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG 156
D C C CR C PL D P G K C C G
Sbjct: 288 DGDHCRNCTCKSGAVECRRM--SCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEG 345
Query: 157 KCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG-- 214
+ I + E+ CP C + H + QC C G CA+G
Sbjct: 346 QRILTKSCRECRGGVLVKITEM-CPPLNCSEKDHI-LPENQCCRV---CRGHNFCAEGPK 400
Query: 215 -SDEVGCVS-----TPKVRSPCISTEFE---CNDRITCVHRA-WVXXXXXXXXXXXXEAL 264
+ C + T + +S IS + + C D C + +
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 265 ELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK------TICDKR 317
+ G + R+D F C +H C G C+ C + ++CT + TIC
Sbjct: 461 DCVPGYI--RVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAF 518
Query: 318 TEFDCG-GGMCIPLSK-VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
E C GG C+ +K VC + E + D C E E +N RCV+ P Y+
Sbjct: 519 CEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDI-DECSEGIIECHN---HSRCVNLPGWYH 574
Query: 376 CDCEKGYK-----LIDNRTCEDIDECA-DPGSC--SQICINEKGTFKCECHTG 420
C+C G+ + +C DIDECA +C CIN G F C C +G
Sbjct: 575 CECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC-----GENEC-EKNNGGCSQRCVDTPIG 373
+C GG+ + ++++C ++C + P ++C G N C E G + C +
Sbjct: 355 ECRGGVLVKITEMCPP-LNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTK 413
Query: 374 YYCDCEKGYKLI--DNRTCEDIDECADPGS---CSQICINEKGTFKCECHTGYAR 423
C+C+ GY + D+ CEDIDECA + +C+N G ++C+C GY R
Sbjct: 414 ATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIR 468
Score = 46.0 bits (104), Expect = 5e-04
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 367 CVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICINEKGTFKCECHTGY 421
CV+ P Y CDC GY +D+ +C + DEC + +C + IC N C C GY
Sbjct: 451 CVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 67.7 bits (158), Expect = 1e-10
Identities = 89/353 (25%), Positives = 125/353 (35%), Gaps = 42/353 (11%)
Query: 97 DEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG 156
D C C CR C PL D P G K C C G
Sbjct: 288 DGDHCRNCTCKSGAVECRRM--SCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEG 345
Query: 157 KCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG-- 214
+ I + E+ CP C + H + QC C G CA+G
Sbjct: 346 QRILTKSCRECRGGVLVKITEM-CPPLNCSEKDHI-LPENQCCRV---CRGHNFCAEGPK 400
Query: 215 -SDEVGCVS-----TPKVRSPCISTEFE---CNDRITCVHRA-WVXXXXXXXXXXXXEAL 264
+ C + T + +S IS + + C D C + +
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 265 ELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK------TICDKR 317
+ G + R+D F C +H C G C+ C + ++CT + TIC
Sbjct: 461 DCVPGYI--RVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAF 518
Query: 318 TEFDCG-GGMCIPLSK-VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
E C GG C+ +K VC + E + D C E E +N RCV+ P Y+
Sbjct: 519 CEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDI-DECSEGIIECHN---HSRCVNLPGWYH 574
Query: 376 CDCEKGYK-----LIDNRTCEDIDECA-DPGSC--SQICINEKGTFKCECHTG 420
C+C G+ + +C DIDECA +C CIN G F C C +G
Sbjct: 575 CECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC-----GENEC-EKNNGGCSQRCVDTPIG 373
+C GG+ + ++++C ++C + P ++C G N C E G + C +
Sbjct: 355 ECRGGVLVKITEMCPP-LNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTK 413
Query: 374 YYCDCEKGYKLI--DNRTCEDIDECADPGS---CSQICINEKGTFKCECHTGYAR 423
C+C+ GY + D+ CEDIDECA + +C+N G ++C+C GY R
Sbjct: 414 ATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIR 468
Score = 46.0 bits (104), Expect = 5e-04
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 367 CVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICINEKGTFKCECHTGY 421
CV+ P Y CDC GY +D+ +C + DEC + +C + IC N C C GY
Sbjct: 451 CVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 67.7 bits (158), Expect = 1e-10
Identities = 89/353 (25%), Positives = 125/353 (35%), Gaps = 42/353 (11%)
Query: 97 DEHQCEVEACGPEEFTCRGKPGECVPLTWMCDDNPDCSDGSDEKACNETCRSDEFTCGNG 156
D C C CR C PL D P G K C C G
Sbjct: 288 DGDHCRNCTCKSGAVECRRM--SCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEG 345
Query: 157 KCIQMRWVXXXXXXXXXXXXEVKCPTPTCQPQSHFSCTDGQCISAWWHCDGDVDCADG-- 214
+ I + E+ CP C + H + QC C G CA+G
Sbjct: 346 QRILTKSCRECRGGVLVKITEM-CPPLNCSEKDHI-LPENQCCRV---CRGHNFCAEGPK 400
Query: 215 -SDEVGCVS-----TPKVRSPCISTEFE---CNDRITCVHRA-WVXXXXXXXXXXXXEAL 264
+ C + T + +S IS + + C D C + +
Sbjct: 401 CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRC 460
Query: 265 ELCRGNVTCRLDQFQCKDHS-CIPGALYCNGVKDCPDGSDEYNCTRQK------TICDKR 317
+ G + R+D F C +H C G C+ C + ++CT + TIC
Sbjct: 461 DCVPGYI--RVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAF 518
Query: 318 TEFDCG-GGMCIPLSK-VCDKHVDCPNFEDEPRDRCGENECEKNNGGCSQRCVDTPIGYY 375
E C GG C+ +K VC + E + D C E E +N RCV+ P Y+
Sbjct: 519 CEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDI-DECSEGIIECHN---HSRCVNLPGWYH 574
Query: 376 CDCEKGYK-----LIDNRTCEDIDECA-DPGSC--SQICINEKGTFKCECHTG 420
C+C G+ + +C DIDECA +C CIN G F C C +G
Sbjct: 575 CECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSG 627
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 321 DCGGGMCIPLSKVCDKHVDCPNFEDE-PRDRC-----GENEC-EKNNGGCSQRCVDTPIG 373
+C GG+ + ++++C ++C + P ++C G N C E G + C +
Sbjct: 355 ECRGGVLVKITEMCPP-LNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTK 413
Query: 374 YYCDCEKGYKLI--DNRTCEDIDECADPGS---CSQICINEKGTFKCECHTGYAR 423
C+C+ GY + D+ CEDIDECA + +C+N G ++C+C GY R
Sbjct: 414 ATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIR 468
Score = 46.0 bits (104), Expect = 5e-04
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 367 CVDTPIGYYCDCEKGYKLIDNRTCEDIDEC-ADPGSCSQ--ICINEKGTFKCECHTGY 421
CV+ P Y CDC GY +D+ +C + DEC + +C + IC N C C GY
Sbjct: 451 CVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGY 508
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/186 (30%), Positives = 83/186 (44%), Gaps = 27/186 (14%)
Query: 265 ELCRGNVTCRLD-QFQCKDHSCIPGALYCNGVKDCPDGSDEYNCTRQKTIC-DKRTEFDC 322
+LC+ + D F+C C PG + C D DE R +C +R E
Sbjct: 891 DLCQSGICTNTDGSFEC---ICPPGHRAGPDLASCLD-VDECR-ERGPALCGSQRCENSP 945
Query: 323 GGGMCIPLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGG-C-SQRCVDTPIGYYCD-- 377
G C+ + CD P + P C + +EC++ C +QRC +TP Y C
Sbjct: 946 GSYRCV---RDCD-----PGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 997
Query: 378 CEKGYKLIDNRTCEDIDECADPGSCS--QICINEKGTFKCECHTGY--ARDPR---DRTR 430
C+ GY+ C+D+DEC + C +C N G+F+C C GY ARD R D
Sbjct: 998 CDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE 1057
Query: 431 CKATEG 436
C+ +G
Sbjct: 1058 CETLQG 1063
Score = 60.9 bits (141), Expect = 2e-08
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 6/83 (7%)
Query: 346 EPRDRCGENECEKNNGGCSQRCVDTPIGYYCDCEKGYKL-IDNRTCEDIDECADPGSCSQ 404
EP + EC +G + RCV P G+ C C GY+L + C DI+EC + + S
Sbjct: 1490 EPYEELEAEECGILDGCTNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 405 ICINEK-----GTFKCECHTGYA 422
+C+N + G+F+C C G+A
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGFA 1572
Score = 60.5 bits (140), Expect = 2e-08
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
Query: 356 CEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLIDNRT-CEDIDECAD-PGSCSQ-ICINEKG 411
C++N C RC+ P GY C C+ G++L T C D+DEC P C+ C N G
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 412 TFKCECHTGYARDPR 426
+F+C C G+ PR
Sbjct: 572 SFRCVCGPGFRAGPR 586
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 16/164 (9%)
Query: 267 CRGNVTCRLDQFQCKDHSC--IPGALYCNGVKDCPDGSDEYNCTRQKTICDKRTEFDCGG 324
C+ C C C +PG+ C CP G C C + CG
Sbjct: 632 CQDVDECTQSPGLCGRGGCKNLPGSFRCV----CPAGFRGSACEEDVDECAQEPP-PCGP 686
Query: 325 GMCIPLSKVCDKHVDCP-NFEDE-PRDRCGE-NECEKNNGGCSQ-RCVDTPIGYYCDCEK 380
G C + H CP F P C + +EC ++ C+ RC +T + C C
Sbjct: 687 GRCD--NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPM 744
Query: 381 GYKL-IDNRTCEDIDECADPGSC-SQICINEKGTFKCE-CHTGY 421
G++ CED+DEC + +C Q C+N G+F+C C +G+
Sbjct: 745 GFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGH 788
Score = 56.0 bits (129), Expect = 5e-07
Identities = 36/114 (31%), Positives = 48/114 (42%), Gaps = 12/114 (10%)
Query: 322 CGGGMCI--PLSKVCDKHVDCPNFEDEPRDRCGE-NECEKNNGGCSQR--CVDTPIGYYC 376
C G C+ P S C CP+ R RC + +EC C C +T + C
Sbjct: 767 CPGQECVNSPGSFQCRT---CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC 823
Query: 377 DCEKGYKLIDNRT--CEDIDECADPGSCSQI--CINEKGTFKCECHTGYARDPR 426
C GY+ R C D++EC + C C+N G+F C C GY PR
Sbjct: 824 SCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877
Score = 55.6 bits (128), Expect = 6e-07
Identities = 49/147 (33%), Positives = 66/147 (44%), Gaps = 24/147 (16%)
Query: 287 PGALYCNGVKDCPDGSDEYNCTRQKTICDKRT-EFDCGGGMCIPLSKVCDKHVDCPNFED 345
P C V +C S+E C Q IC F+C +C P + C + D
Sbjct: 876 PRGASCLDVDEC---SEEDLC--QSGICTNTDGSFEC---ICPPGHRAGPDLASCLDV-D 926
Query: 346 EPRDRCGENECEKNNGGCSQRCVDTPIGYYC--DCEKGYKLIDNRTCEDIDECAD--PGS 401
E R+R G C SQRC ++P Y C DC+ GY TC+D+DEC + P
Sbjct: 927 ECRER-GPALCG------SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEI 979
Query: 402 C-SQICINEKGTFKC--ECHTGYARDP 425
C +Q C N G+++C C GY P
Sbjct: 980 CGAQRCENTPGSYRCTPACDPGYQPTP 1006
Score = 49.6 bits (113), Expect = 4e-05
Identities = 28/72 (38%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 367 CVDTPIGYYCDCEKGYKLIDNR-TCEDIDECAD--PGSCSQICINEKGTFKCECHTGYAR 423
CV+T GY C C GY R C D DECAD P C+N G++ C C
Sbjct: 1233 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVL 1292
Query: 424 DPRDRTRCKATE 435
D R RC + E
Sbjct: 1293 DGSQR-RCVSNE 1303
Score = 48.8 bits (111), Expect = 7e-05
Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 22/146 (15%)
Query: 287 PGALYC---NGVKDCPDGS---DEYNCTRQKTICDKRTEFDCGGGMCIPLSKVCDKHVDC 340
PG+ C G + P G+ D CT+ +C + GG +P S C C
Sbjct: 612 PGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR------GGCKNLPGSFRCV----C 661
Query: 341 P-NFEDEPRDRCGENECEKNNGGCSQ-RCVDTPIGYYCDCEKGYKLID-NRTCEDIDECA 397
P F + +EC + C RC +T ++C C G++ C+D+DECA
Sbjct: 662 PAGFRGSACEE-DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECA 720
Query: 398 -DPGSCSQ-ICINEKGTFKCECHTGY 421
P C+ C N +G+F+C C G+
Sbjct: 721 RSPPPCTYGRCENTEGSFQCVCPMGF 746
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 313 ICDKRTEFDCGGGMCIPLSKVCDKHVDCPN-FEDEPRD-RCGE-NECEKNNGGCSQ-RCV 368
+C + + CG G CI S+ C + F P+ RC + +EC + C+ RC
Sbjct: 511 MCQRNPQV-CGPGRCI--SRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE 567
Query: 369 DTPIGYYCDCEKGYKLIDNRT-CEDIDECAD-PGSCSQ-ICINEKGTFKCECHTGYARDP 425
++P + C C G++ C D+DEC P C C N G+F C C GY P
Sbjct: 568 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 627
Score = 46.8 bits (106), Expect = 3e-04
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 9/83 (10%)
Query: 352 GENECE--KNNGGCSQRCVDTPIGYYCDCEKGYKLIDNRTCEDIDECADPGSCSQ-ICIN 408
G ++C+ G S+R V P G C G++ + N +CED+DECA G C C N
Sbjct: 283 GVHDCQLCSERLGNSER-VSAPDG---PCPTGFERV-NGSCEDVDECATGGRCQHGECAN 337
Query: 409 EKGTFKCECHTGYARDPRDRTRC 431
+G + C C G+ D R+ C
Sbjct: 338 TRGGYTCVCPDGFLLD-SSRSSC 359
Score = 32.7 bits (71), Expect = 5.0
Identities = 27/108 (25%), Positives = 39/108 (36%), Gaps = 9/108 (8%)
Query: 280 CKDHSCIPGALYCNGVKDCPDG------SDEYNCTRQKTICDKRTEFDCGGGMCIPLSKV 333
C+ C PG CP G S + + R C + C G+C+ +
Sbjct: 1181 CRIQQC-PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1239
Query: 334 CDKHVDCPNFEDEPRDRCGEN-ECEKNNGGCSQ-RCVDTPIGYYCDCE 379
+ + R C +N EC C RCV+T Y+C CE
Sbjct: 1240 YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1287
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.473
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 133,238,980
Number of Sequences: 224733
Number of extensions: 6483607
Number of successful extensions: 30136
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 495
Number of HSP's successfully gapped in prelim test: 460
Number of HSP's that attempted gapping in prelim test: 13371
Number of HSP's gapped (non-prelim): 6777
length of query: 766
length of database: 73,234,838
effective HSP length: 96
effective length of query: 670
effective length of database: 51,660,470
effective search space: 34612514900
effective search space used: 34612514900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)
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