Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002651-TA|BGIBMGA002651-PA|IPR013132|N-acetylneuraminic
acid synthase, N-terminal
(349 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 321 1e-86
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 251 2e-65
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 193 7e-48
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 190 4e-47
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 188 2e-46
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 186 8e-46
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 182 9e-45
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 175 1e-42
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 173 4e-42
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 172 1e-41
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 170 5e-41
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 167 5e-40
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 165 2e-39
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 161 3e-38
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 156 7e-37
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 155 2e-36
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 154 4e-36
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 154 4e-36
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 153 7e-36
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 153 9e-36
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 152 2e-35
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 146 8e-34
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 146 8e-34
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 144 3e-33
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 144 3e-33
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 144 3e-33
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 143 5e-33
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 139 9e-32
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 136 6e-31
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 136 8e-31
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 135 2e-30
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 134 2e-30
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 134 2e-30
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 134 4e-30
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 133 6e-30
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 132 2e-29
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 132 2e-29
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 131 2e-29
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 130 4e-29
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 130 4e-29
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 130 5e-29
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 130 5e-29
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 129 1e-28
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 127 4e-28
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 126 6e-28
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 124 3e-27
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 124 5e-27
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 123 6e-27
UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum gryphiswald... 122 1e-26
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 121 2e-26
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 121 2e-26
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 121 2e-26
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 120 7e-26
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 114 3e-24
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 113 5e-24
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 113 9e-24
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 113 9e-24
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 111 3e-23
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 110 5e-23
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 110 6e-23
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 108 2e-22
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 107 3e-22
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 107 4e-22
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 106 7e-22
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 106 1e-21
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 105 2e-21
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 104 3e-21
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 102 1e-20
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 100 5e-20
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 99 9e-20
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 99 2e-19
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 97 5e-19
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 95 2e-18
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 90 9e-17
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 89 2e-16
UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase, N-ter... 85 3e-15
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 73 8e-12
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 73 1e-11
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 73 1e-11
UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid ... 72 2e-11
UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix o... 58 3e-07
UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus... 58 5e-07
UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide bios... 55 2e-06
UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase, N-ter... 51 4e-05
UniRef50_Q9P0B2 Cluster: HSPC269; n=2; Homo sapiens|Rep: HSPC269... 51 5e-05
UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis ... 47 8e-04
UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide bios... 42 0.018
UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;... 38 0.52
UniRef50_Q55G26 Cluster: Putative uncharacterized protein; n=1; ... 35 3.6
UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein... 34 4.8
UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;... 34 6.3
UniRef50_Q7VQK1 Cluster: Survival protein SurA; n=1; Candidatus ... 33 8.4
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 321 bits (789), Expect = 1e-86
Identities = 157/345 (45%), Positives = 214/345 (62%), Gaps = 1/345 (0%)
Query: 2 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 61
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 62 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFL 121
+K LERPY + +SWGKTYGEHK HLEFS QYREL RYA+EVGI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 122 VNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLL 181
L VPF K+GSGD+NN +L+ A K P++IS+GM +K +Y I+ + FC L
Sbjct: 123 HELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFL 182
Query: 182 HCISAYPVPFEDCNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLD 240
C SAYP+ ED NL V+ +Y+ F D+P+GYSG E E+HITLD
Sbjct: 183 QCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLD 242
Query: 241 KSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKN 300
K+ KG+DH SL P E +LVR VR++E +LG+P K+++ E+ C +KL KS+V
Sbjct: 243 KTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIP 302
Query: 301 KGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNE 345
+G IL + +KV EPKG + +++ K ++ +ED+ + E
Sbjct: 303 EGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIME 347
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 251 bits (614), Expect = 2e-65
Identities = 144/350 (41%), Positives = 195/350 (55%), Gaps = 25/350 (7%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
+IIAE GQNHQG G CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 138
TYGEHK +LEFS QY +L + +E+ + FTASAMD S +FL L VPFIKIGSGD+NN
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 139 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FCLLHCISAYPVPFEDCNLT 197
LK AA+ +PL+ISTGM V+ I + K+ + L+HC+S+YP +DC+L
Sbjct: 136 FPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQ 195
Query: 198 VLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSE 256
++ + F +V +GYSG E E+H TLDKS KG+DH CSL P E
Sbjct: 196 LISVLRTRFPNVAIGYSGHELGVIISQAAVLLGARIVERHFTLDKSQKGSDHRCSLEPQE 255
Query: 257 F-------------------QQLVRDV---RVIEASL-GTPIKKVVTSEIPCIDKLQKSL 293
Q++V+ + +EA+L K ++ E+PC +KL KS+
Sbjct: 256 LKALTTAITNFKLSSVPMPPQEIVKKLNGDEELEAALQHVESKTILPCELPCRNKLGKSI 315
Query: 294 VMGSTKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
V NKG L D+ IKV+EP GL A D++ K L + EDEP+
Sbjct: 316 VAARNLNKGYRLQLADMAIKVSEPSGLTAEDFLDLVGKELADNIGEDEPI 365
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 193 bits (470), Expect = 7e-48
Identities = 115/340 (33%), Positives = 168/340 (49%), Gaps = 6/340 (1%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
+IG P FIIAE G NH G GA CVKFQ + + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNEGDDD-- 180
Query: 71 DNPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 129
D G Y + + D ++ E+F Y ++ IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 130 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 189
K+ S D N LKY A+KK+PLI+STGM + + + +++ + F LLHC S YP
Sbjct: 241 KVASADLTNHRLLKYLAAKKVPLILSTGMSVEQEIISAVELLEKESASFALLHCNSTYPA 300
Query: 190 PFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
PF+D NLT L+ K+ VGYSG E EKH T+DKSM+G DH
Sbjct: 301 PFKDVNLTYLKRLKSLGRTVVGYSGHERGYAIPIASIPLGAKIVEKHFTIDKSMEGNDHK 360
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTP-IKKVVT-SEIPCIDKLQKSLVMGSTKNKGEILYP 307
SL P EF ++V+ +R +E SLG+P I K +T E+ + L KS+V KG+++
Sbjct: 361 VSLLPDEFNEMVKAIRAVEESLGSPEISKTITQGEMMNRETLAKSVVADVNIKKGDVITE 420
Query: 308 GDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+ IK + KGL L +++ + V D +++ L + D
Sbjct: 421 EMLAIK-SPGKGLAPYKLSELVNRVAVRDIPKNDFLYQSD 459
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 190 bits (464), Expect = 4e-47
Identities = 113/338 (33%), Positives = 164/338 (48%), Gaps = 4/338 (1%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
RI P +IIAE G NH G+ GA+ VKFQK L + + + L+ P
Sbjct: 14 RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYREDVLKDP- 72
Query: 71 DNPNSWG-KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 129
N S G + + + +EF D Y+EL Y +E I F + D+ S +FL +P
Sbjct: 73 -NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFLEKFDLPAY 131
Query: 130 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 189
KI S D N + PLI+STGM + ++ + + +F LLHC S YP
Sbjct: 132 KIASADMTNFPLISSLIQTGKPLIVSTGMSNMNEIEKTVSFMKEKNAKFALLHCNSTYPA 191
Query: 190 PFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
P E NL ++ K F V +GYSG E E+HITLDK+M+G D
Sbjct: 192 PVETLNLELISLLKEKFQVLIGYSGHEPGIVSTLAAVMLGAIIVERHITLDKTMEGLDQA 251
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGD 309
SL P EF++LV+D+R E + G PIKK+ EI + L KS+ + K EI +
Sbjct: 252 ASLEPDEFKKLVKDIREAEKAKGKPIKKMTRGEILQKEVLGKSITAKNDIKKDEIFSENN 311
Query: 310 VKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+ IK KGL+ + +++ K + K ++ L + D
Sbjct: 312 LAIK-GPAKGLSPQYYYEILGKKSKREIKRNDYLQDDD 348
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 188 bits (458), Expect = 2e-46
Identities = 108/338 (31%), Positives = 162/338 (47%), Gaps = 6/338 (1%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 75
NP F+IAE G NHQGD GA VK QK FT + + YD+ N+
Sbjct: 16 NPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYDSENA 75
Query: 76 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 135
+ TYG H+ LEF+ QY EL Y +++ ILF ++A D S + L + +P KI SGD
Sbjct: 76 YAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKIASGD 135
Query: 136 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCN 195
N LK AS P+I+STG + Y+ I ++ C++ C S YP P E+ N
Sbjct: 136 LVNTPLLKKVASYGKPIIVSTGGGTLADARLAYETIMPINRNLCIMQCTSGYPPPHEELN 195
Query: 196 LTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTP 254
L V++ ++ F D+ +G+S + EKH TL+++ KGTD SL P
Sbjct: 196 LRVIETFRREFPDIVIGFSSHDSGIAMPLVGYMLGARVFEKHFTLNRTWKGTDQAFSLEP 255
Query: 255 SEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIKV 314
+++VRD+ +LG +K SE ++K+ K +V KG +L D+ ++
Sbjct: 256 QGLRRVVRDLDRTRQALGDGVKVPYASETGPLNKMVKRVVAARELKKGHMLAAEDLAFRI 315
Query: 315 -----AEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
L E ++ L D +EP+ D
Sbjct: 316 PVGAKITSHTLRPFEAEQIVGHALKRDIGFEEPITRVD 353
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 186 bits (453), Expect = 8e-46
Identities = 111/342 (32%), Positives = 171/342 (50%), Gaps = 16/342 (4%)
Query: 1 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 60
M ++KI D +G P FIIAE G NH GD GA +KFQ +
Sbjct: 1 MEKIKIGDRY-VGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSYHTEDF 59
Query: 61 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 120
+KK Y E LE S+ ++ EL YA+++GI+F ++ +D+ D
Sbjct: 60 ISKK-------------SEYYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 121 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFC 179
L + VP KI SGD L+ A P+I+STGM D + ++ ++ +
Sbjct: 107 LNKMNVPAFKIASGDLTFYPLLEKVAKTGKPVILSTGMSDIGEIWEAVKVLENNGCRDII 166
Query: 180 LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITL 239
LLHCIS+YP P+ED NL ++ K+ F++PVGYS EKH TL
Sbjct: 167 LLHCISSYPTPYEDVNLNAIKTLKSIFNIPVGYSDHTLGILAPVVSVALGADVIEKHFTL 226
Query: 240 DKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTK 299
DK+M+G DH S P EF+++V ++R++E LG+ K + SE I + ++S+V
Sbjct: 227 DKNMEGPDHALSADPEEFKEMVNNIRLVEKMLGSGEKIPMPSERDVIVEARRSIVAKRNI 286
Query: 300 NKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDE 341
KGE L ++ K +G+ +L ++ + + DK+ED+
Sbjct: 287 KKGEYLSVDNISFK-RPGRGIETKYLSIILNRKIKNDKEEDD 327
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 182 bits (444), Expect = 9e-45
Identities = 97/280 (34%), Positives = 145/280 (51%), Gaps = 4/280 (1%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
+G + PC++IAE G NH GD G VKFQK + +T L +P +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAKPRE 79
Query: 72 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
NP +G T G+ K LEF +++E+ RY +EV + + ASA D S DF+ VP KI
Sbjct: 80 NP--FGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 191
S + L++ + P+++STGM + D++ D+ LL S YP +
Sbjct: 138 ASASLTDDNLLRHTRATGKPVMLSTGMSTVEQIDHAVDVLGKDN--LILLQACSTYPAYY 195
Query: 192 EDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
E+ NL + + + VPVGYSG E E+HITLD++M G+D S
Sbjct: 196 EELNLKAIHTLMDRYGVPVGYSGHETGLPASIAAAAMGACVLERHITLDRAMWGSDQAAS 255
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQK 291
L P+ QLVR +R++E S+G +K+V+ E P I KL++
Sbjct: 256 LEPNGITQLVRYLRIVEKSMGDGVKRVLEREQPVIQKLRR 295
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 175 bits (427), Expect = 1e-42
Identities = 107/333 (32%), Positives = 161/333 (48%), Gaps = 5/333 (1%)
Query: 14 GNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 73
G FIIAEAG NH G G VKFQ T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 74 NSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
N+ ++ +++ LE S+ + L+ Y QE GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPVP 190
S D NN+ FLK+ A KK P+IISTGM ++ + + ++ + + LLHC+++YP
Sbjct: 130 SSTDLNNIPFLKHIAKKKKPVIISTGMGTLCEIEEAVTALKNAGNHEIMLLHCVTSYPAK 189
Query: 191 FEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVC 250
E NL V+ +N F + VG+S EKH TLD + G DH
Sbjct: 190 DESLNLNVIHTLRNAFKLDVGFSDHSLGIYASIAAVSMGATIIEKHFTLDNELPGPDHKA 249
Query: 251 SLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDV 310
SL P++ ++LV +R +E + G IK++ EI ++S+V + I+ D+
Sbjct: 250 SLNPTQLKELVIGIRSVEKAFGDGIKRLTEEEIEIKKVARRSIVTKKDIAENSII-TEDM 308
Query: 311 KIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
I G+ +L+D+I K + D K+D L
Sbjct: 309 IILKRPGTGIKPKYLQDIIGKKVKKDVKKDSVL 341
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 173 bits (422), Expect = 4e-42
Identities = 105/292 (35%), Positives = 146/292 (50%), Gaps = 8/292 (2%)
Query: 18 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPNS- 75
CFIIAEAG NH GD GA VKFQ T + K +E+ Y N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQ-TFKADTLVNKTVEKAEYQKNNAP 61
Query: 76 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 135
T E LE S+ + L A +GI F ++ D S DFL++L V +KI SG+
Sbjct: 62 ESSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSGE 121
Query: 136 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-----SSDHKQFCLLHCISAYPVP 190
N+ +L++ ASKK+PLIISTGM D V+ D + +S LLHC S YP
Sbjct: 122 ITNVPYLQHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLSDYLVLLHCTSNYPAS 181
Query: 191 FEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVC 250
++D NL +Q + F +PVGYS EKH T+DKS+ G DH+
Sbjct: 182 YQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTMDKSLPGPDHLA 241
Query: 251 SLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKG 302
S+ P E + LV+ +R E LG+ KK +E+P +++S+ + KG
Sbjct: 242 SMDPEEMKNLVQSIRDAETVLGSGEKKPSDNELPIRALVRRSITLRRDLVKG 293
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 172 bits (419), Expect = 1e-41
Identities = 113/332 (34%), Positives = 157/332 (47%), Gaps = 6/332 (1%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPN 74
N +IIAEAG NH G GA VKFQ T EK + E Y N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQ-TWKTEKIVTRNAELAVYQENN 61
Query: 75 SWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIG 132
KT + K LE S + + + E+GI F ++ ++ S DFL N +PFIK+G
Sbjct: 62 ISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLG 121
Query: 133 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIY-DIISSDHKQFCLLHCISAYPVPF 191
SGD N+ FL+ S+ I +++STGM V+ Y +I + K LLHC + YP P
Sbjct: 122 SGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCPM 181
Query: 192 EDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
+ NL +Q K+ F VGYS EKH TLDK M G DH S
Sbjct: 182 HEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKAS 241
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVK 311
L P E +Q+V +R IE +LG IK+ SE + + K +V + +GE+L ++
Sbjct: 242 LNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNMT 301
Query: 312 IKVAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
+K GL A + V + + DEP+
Sbjct: 302 VK-RSTVGLKASLWDLVNGRIATCNYAIDEPI 332
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 170 bits (413), Expect = 5e-41
Identities = 104/343 (30%), Positives = 163/343 (47%), Gaps = 6/343 (1%)
Query: 9 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 68
++ +G NP ++IAE G NH GD GA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 69 --PY-DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 125
Y D +G K++ + + Q+RE Y +E GI F ++ D L +L
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTY-QLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLD 126
Query: 126 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCI 184
VPF KI S D +L FLKY A K+ P+++STGM ++ + + ++ + Q LLHC+
Sbjct: 127 VPFFKIASMDIVHLPFLKYVARKRRPMLLSTGMATLAEIEAAVETVRAEGNDQVVLLHCV 186
Query: 185 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
S YP +E +L + + FDVPVG+S EKH TLD+ M+
Sbjct: 187 SIYPPDYEMIHLRNMATLQQAFDVPVGFSDHTMGTAIPLAAIALGACVIEKHFTLDQDME 246
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
G DH S TP++ + +V + R I +LG + V +E+ K ++SLV +G +
Sbjct: 247 GWDHAISATPTDLRTIVEEGRNIRIALGGGKRIVTEAEMEKRKKFRRSLVTRRALPQGHV 306
Query: 305 LYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
L D+ K G++ + + + L D +ED+ + D
Sbjct: 307 LVEADLDAK-RPGTGISPAEMTYALGRRLARDMQEDDVIRWED 348
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 167 bits (405), Expect = 5e-40
Identities = 103/333 (30%), Positives = 158/333 (47%), Gaps = 7/333 (2%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
IG +PCF+IAE G NH GD GA C KFQ +G+ ++ + D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 72 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
+ G Y + + SD + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 131 IGSGD-SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 189
+ S D +N+ L + AA+ K PLI STGM + +++ + + LLHC S YP
Sbjct: 246 VASADFTNHALITQLAATGK-PLICSTGMASELEIRSGIRHLQKAGANYVLLHCNSTYPT 304
Query: 190 PFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
PF+D NL L+ + D PVGYSG E EKHITLD+ M+G DH
Sbjct: 305 PFKDVNLRYLERLRELADAPVGYSGHERGIEIPLAAAALGAVVIEKHITLDRGMEGNDHK 364
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVT-SEIPCIDKLQKSLVMGSTKNKGEILYPG 308
SL P EF Q++ +R +E S+G ++ ++ E+ + L KSLV + G +
Sbjct: 365 VSLLPDEFSQMILGIRRVEESMGQGGERSISQGEMMNREVLAKSLVASCDIDAGTTITEA 424
Query: 309 DVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDE 341
V+I+ + +GL L +++ + L KK+ +
Sbjct: 425 MVRIQ-SPGQGLQPNRLHELVGQKLPISKKKGD 456
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 165 bits (400), Expect = 2e-39
Identities = 92/301 (30%), Positives = 142/301 (47%), Gaps = 2/301 (0%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
IG + CF+IAEAG NH GD GA +KFQ + + Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 72 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
N+ ++ E LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 131 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPV 189
+ SGD N L+ A+K P+IISTGM + ++ + + ++ ++ C L C S+YP
Sbjct: 143 VSSGDLTNHFLLEAVAAKGKPVIISTGMANLADIEGALACLRTAGAREVCALQCTSSYPA 202
Query: 190 PFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
P + NL + + F +P+GYS EKH+TLD+S+ G DH
Sbjct: 203 PPDQINLRTIATMRAAFGIPIGYSDHTLGIPVAIAAATLGAAVIEKHVTLDRSLLGPDHS 262
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGD 309
SL P E +++ +R +EA+LG+P+K+ + E + ++SL G ++ D
Sbjct: 263 ASLVPEELSRMIAGIREVEAALGSPVKRPMQIEEDTREVARRSLFAARDIEAGGVIGRSD 322
Query: 310 V 310
+
Sbjct: 323 L 323
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 161 bits (390), Expect = 3e-38
Identities = 107/347 (30%), Positives = 153/347 (44%), Gaps = 4/347 (1%)
Query: 1 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 60
M +KI +D I +PCFIIAEAG NH G G CVKFQ
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 61 FTKKYLERPYD-NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFD 119
TKK + Y ++ E LE S Y ++ + I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 120 FLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQF 178
FL L V KI SG L FL++ A P+I+S+GM V + + I + + Q
Sbjct: 120 FLNKLGVSAFKIASGQIVELAFLEHVAKFGKPIILSSGMATLAEVYEAVMTIREAGNNQM 179
Query: 179 CLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHIT 238
+L C + YP ED N+ + N+ D+ GYS EKH T
Sbjct: 180 AILQCTTNYPSQNEDANIRAMISMGNSLDLIYGYSDHIEENYACFAAVALGAKVIEKHFT 239
Query: 239 LDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGST 298
LD+++ G DH SL EF L+ +R E +LG+PIK+ EI +++S+V+ S
Sbjct: 240 LDRNLPGPDHKASLNVLEFGSLIEGIRKTETALGSPIKRPSLKEIQNTKGMRRSIVLNSP 299
Query: 299 KNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNE 345
KGE + G++ K G+ +D+I K D D PL E
Sbjct: 300 IKKGETITMGNMAFK-RPATGIAPKRKKDLIGKKAAVDIDLDVPLKE 345
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 156 bits (379), Expect = 7e-37
Identities = 100/348 (28%), Positives = 163/348 (46%), Gaps = 16/348 (4%)
Query: 1 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 60
M ++KI + I IG +PCFIIAEAG NH GD GA+ VKFQ +
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 61 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 120
F+K + N K + EF ++E+ Y + GI+F + + D
Sbjct: 60 FSKNH------PANKIVKNF-------EFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 121 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FC 179
L L + KI SGD + L Y ++ P+I+++GM VK ++ I + +
Sbjct: 107 LEKLNIEGYKIASGDMDYYPLLDYISNTGKPIILASGMAYMDEVKEAFNRIKNGKTEDIA 166
Query: 180 LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITL 239
+LHC+S YP ED NL +Q K F+VPVG+S EKH T+
Sbjct: 167 ILHCVSNYPPKDEDINLKAIQTIKEEFNVPVGFSDHSMGITVPIAAVALGANIIEKHFTI 226
Query: 240 DKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTK 299
+ ++G DH +L P E +Q+V ++R +E S+G IK V +E ++ ++
Sbjct: 227 SRKLEGMDHFYALEPKELKQMVIEIRKVEKSMGVGIKTPVKAEFAERHYARRGIIAACNL 286
Query: 300 NKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+G+++ + V G+ + + E+VI + + + D P++ D
Sbjct: 287 KEGQVI-KEEYLDYVRPVDGIESKYYEEVIGRKVNKNIDVDSPIHWED 333
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 155 bits (375), Expect = 2e-36
Identities = 102/340 (30%), Positives = 149/340 (43%), Gaps = 6/340 (1%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
RI +P +I+AE G NH G+ GA VKFQ E + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 71 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
N+ E S + EL+R+ GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 131 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS--SDHKQFCLLHCISAYP 188
SG+ N + L AA ++P+I+STGM + + + D I+ + +L C+S YP
Sbjct: 131 WASGELTNKMLLDQAAKTRLPIILSTGM---SRINDVDDAITWIGRNTPLVVLQCVSNYP 187
Query: 189 VPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDH 248
D NL VL +N + PVG+S EKH TLD+++ G DH
Sbjct: 188 AAMSDQNLRVLPFLENRYQCPVGFSDHTQGFQCAIAAKGLGMSVLEKHFTLDRNLDGPDH 247
Query: 249 VCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPG 308
S+ + ++LV +VR IE +LG +K SE+ +KSL + G I+
Sbjct: 248 KASVDFTGLKELVSEVRSIEVALGNGVKLPAPSELDAKTVARKSLFYARSLKAGHIITKN 307
Query: 309 DVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
D+ K G+ E + K L D +D L+ DF
Sbjct: 308 DLAAK-RPSFGIPPSEYEAFLGKQLKIDSVKDVALSYEDF 346
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 154 bits (373), Expect = 4e-36
Identities = 98/296 (33%), Positives = 131/296 (44%), Gaps = 3/296 (1%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN-SWG 77
++IAE G NH G GA+ VKFQ + +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 78 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 137
+ E LE S + + + Y + I F ++ D S DFL + V KIGSGD
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 138 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLT 197
NL FL+ +P+++STGM D V D +LHC S YP ED NL
Sbjct: 127 NLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFIDS--PVTILHCTSNYPASSEDINLL 184
Query: 198 VLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEF 257
+ K F +PVGYS EKH TLDK + G DH SL P EF
Sbjct: 185 AINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEF 244
Query: 258 QQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIK 313
V+ +R E LG +K+ + SE+ + +KSLV+ N G+IL + IK
Sbjct: 245 ADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIK 300
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 154 bits (373), Expect = 4e-36
Identities = 90/279 (32%), Positives = 135/279 (48%), Gaps = 4/279 (1%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
++IAE G NH GD G VKFQK + ++ + L RP +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPRENV--FGT 65
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 138
T G+ K LEF Y + + +E+GI + AS D S DFL++ P+IK+ S +
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVASAMVTD 125
Query: 139 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNLT 197
FL+Y A PL++STGM D VK+ D+I S + CL HC S YP ++ NL
Sbjct: 126 RDFLEYCARSGRPLLVSTGMSDMAMVKSFVDVIERSGGEIACLYHCTSTYPTRDDEINLR 185
Query: 198 VLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSE 256
+ K F + +G+SG E E+H+TLD+S G+D SL E
Sbjct: 186 GISTLKEAFPHLKIGFSGHEEGILPSVCAAALGACSIERHVTLDRSDWGSDQKASLEMPE 245
Query: 257 FQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVM 295
+V +R +E G + + E P +KL++ + +
Sbjct: 246 VADMVSQIRRVEIVRGDGVLRFYEDEKPIAEKLRRKVTL 284
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 153 bits (371), Expect = 7e-36
Identities = 97/291 (33%), Positives = 132/291 (45%), Gaps = 2/291 (0%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 75
N F++AEAG NH G GA +KFQ T + Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 76 WGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
T E S LE S++Q+R + + VGI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFED 193
D +L FL++ A K P+IISTGM + ++ D I ++ +LHC+S YP
Sbjct: 133 DLTHLAFLQHVARKGRPMIISTGMANLADIEEAVDAIEAAGSPPLAILHCVSDYPADPAS 192
Query: 194 CNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLT 253
NL + F PVG+S EKH TLDKS+ G DH+ SL
Sbjct: 193 SNLMAIPTLAAAFRRPVGWSDHTLGEATSLASIPLASKMIEKHFTLDKSLPGPDHIASLE 252
Query: 254 PSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
P E + V ++R IE +LG K+ E ++SLV KGE+
Sbjct: 253 PDELVRFVANIRTIEVALGDGRKRPHDVERDTARVARRSLVTLKEVKKGEL 303
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 153 bits (370), Expect = 9e-36
Identities = 83/268 (30%), Positives = 132/268 (49%), Gaps = 5/268 (1%)
Query: 48 SCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGIL 107
+ VK K L E+ + + YDNPNS+G+TYGEH++ LE D + E+++YA+ +G+
Sbjct: 45 NAVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD 104
Query: 108 FTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTI 167
F + L +K+ S D NL L+ A IP+I+STGM + +
Sbjct: 105 FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNA 164
Query: 168 YDIISSDHKQFCLLHCISAYPVPFEDCNL---TVLQDYKNTFDVPVGYSGQEXXXXXXXX 224
D+I+ H +LHC+S YP + NL T L+ + N F+ +G+S
Sbjct: 165 LDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFE--IGFSDHTIGISAATA 222
Query: 225 XXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIP 284
EKH+T+D+ MKGTD + SL P +++RD+R+ E LGT +
Sbjct: 223 AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVEK 282
Query: 285 CIDKLQKSLVMGSTKNKGEILYPGDVKI 312
KL++S+ G I+ D+ +
Sbjct: 283 SKIKLERSIATRKYIPAGSIIQESDIHL 310
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 152 bits (368), Expect = 2e-35
Identities = 87/272 (31%), Positives = 127/272 (46%), Gaps = 2/272 (0%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
F+IAE G NH GD G VKFQK + +T + L +P +P WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVLAQPRQSP--WGD 91
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 138
T K LEF +Y + Y +E+G+ + ASA D+ S FL +P+ KI S +
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIASAMLTH 151
Query: 139 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 198
++ A++ + STGM + T +I+ + F L+H +S YP P D NL
Sbjct: 152 RPLIEAVAAEGKLVFASTGMCTFEQIDTAVEILRAAACPFVLMHTVSTYPTPPADLNLLT 211
Query: 199 LQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQ 258
+ + + PVGYSG E E+HITLD++M G+D SL P E +
Sbjct: 212 IDTLRRRYGAPVGYSGHESSVEPSLVAAMLGAVAIERHITLDRTMYGSDQSASLEPDELK 271
Query: 259 QLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQ 290
LV +R + LG K++ E KL+
Sbjct: 272 VLVSRLRDLREWLGDGEKRITPGEASVAGKLR 303
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 146 bits (354), Expect = 8e-34
Identities = 97/338 (28%), Positives = 145/338 (42%), Gaps = 6/338 (1%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
+G PC++IAE G NH GD GA C KFQ L E + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLSGK-D 77
Query: 72 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
+ + T + E + Q +++ Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 191
S D NL L + LI+STGM +K + + + LLHC S YP
Sbjct: 137 ASADLTNLPLLARLIATGKTLIVSTGMSTTEEIKAAAEFLDERKAGYVLLHCQSTYPAAL 196
Query: 192 EDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
+ +L + + + VGYSG E E+HITLD+ M+G DH S
Sbjct: 197 HNIHLRFMDTLREIHPL-VGYSGHERGTAVSTAAVALGAIVIERHITLDREMEGPDHAAS 255
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDK--LQKSLVMGSTKNKGEILYPGD 309
L P EF+ LV +R +EA+ G + + S+ I++ L KSLV G ++ D
Sbjct: 256 LEPEEFKALVTGIREVEAARGEKLAERALSQGELINRENLAKSLVAARDIEAGTVISDDD 315
Query: 310 VKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+ +K + +GL+ L + +I K L D+ + D
Sbjct: 316 IAVK-SPGQGLSPLKMPALIGKILKRKMAADDYFFQSD 352
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 146 bits (354), Expect = 8e-34
Identities = 91/309 (29%), Positives = 146/309 (47%), Gaps = 15/309 (4%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
+IG N P +I+AE G NH GD G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQT------YTAKELVSDT 64
Query: 71 DNPNSWG-------KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN 123
D +WG +T G+ + ++E+F YA ++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 124 LKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDK-TAVKTIYDIISSDHKQFCLLH 182
L+VP K+ + D + L LK K P+++S G A I +I S ++ ++H
Sbjct: 125 LEVPCFKVAASDVDYLDILKEIGKTKKPVMLSLGKCTLGEADLAIETLIESGCEKIVIMH 184
Query: 183 CISAYPVPFEDCNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDK 241
C+S YP P + NL V++ K+ + + +G+S EKH TLDK
Sbjct: 185 CVSQYPSPINEMNLKVIEGLKSIYPEFVIGFSDHSMGITADLGAVALGARVIEKHFTLDK 244
Query: 242 SMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNK 301
+ G DH S+ P + + LVR+VR +EA++G P K+V+ E +SLV+ K
Sbjct: 245 NTDGPDHWFSMDPEDMKSLVREVRNLEAAMGHPRKRVLKCEEQGRKNSIRSLVVNRDIMK 304
Query: 302 GEILYPGDV 310
GE++ D+
Sbjct: 305 GEVIKKEDL 313
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 144 bits (349), Expect = 3e-33
Identities = 102/325 (31%), Positives = 139/325 (42%), Gaps = 35/325 (10%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ----KTCLGEKFTKK-YLERPYDNPN 74
IIAEAG NH G GA VKFQ K G K Y +R D
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 75 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
S LE + L A E GI F ++ D S FL++LK+P IKIGSG
Sbjct: 67 SQLAML----ERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSG 122
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH------------------- 175
D N L AA LI+STGM + ++ +++ +
Sbjct: 123 DLTNAPLLHAAARAGATLILSTGMATLSEIEEALGVLAHGYAQRSDPAGVASFRAAWRDP 182
Query: 176 -------KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXX 228
+ LLHC + YP P ED NL + ++ F +PVGYS
Sbjct: 183 AARATLARHVSLLHCTTEYPCPIEDVNLAAMATMRSAFQLPVGYSDHTDGFEISVAAVAL 242
Query: 229 XXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDK 288
EKH+TLD++ G DH SL P +F ++V +R +EA+LG +K SE+ +
Sbjct: 243 GATVIEKHLTLDRNAPGPDHAASLEPGDFGRMVSAIRNVEAALGDGVKTPKESEVRNVPV 302
Query: 289 LQKSLVMGSTKNKGEILYPGDVKIK 313
+KS+V GEI+ P D+ K
Sbjct: 303 ARKSIVAARALRAGEIIGPADITAK 327
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 144 bits (349), Expect = 3e-33
Identities = 105/340 (30%), Positives = 154/340 (45%), Gaps = 13/340 (3%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG- 77
+I+AE G NH GD G VKFQ T E+ KY + G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 78 -KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 136
+T E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 137 NNLLFLKYAASKKIP---LIISTGM--VDKT--AVKTIYDIISSDHKQFCLLHCISAYPV 189
NL +L+ A I +++STGM VD+ A+K D H+ +LHC + YP
Sbjct: 128 LNLPYLEKIAKLPIEDKKIVLSTGMATVDEINLALKVFIDN-GITHRNITILHCNTEYPT 186
Query: 190 PFEDCNLTVLQDYKNTFD-VPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDH 248
PFED NL + +K F +G+S EKH TLDK+ +G DH
Sbjct: 187 PFEDVNLNTISGFKKIFSQYNIGFSDHSPGYFAGIASVPYGITFIEKHFTLDKNFEGPDH 246
Query: 249 VCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPG 308
S+TP E + L +R +E SLG+ K V SE +KS+V KG+I
Sbjct: 247 KASVTPEELKLLCEGIRAVEISLGSYEKLVTNSERKNKVVARKSIVAKCAIKKGDIFTTE 306
Query: 309 DVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
++ K G++ ++ +V+ K D ED+ + DF
Sbjct: 307 NITTK-RPGNGISPMYWYEVLGKIAEKDFDEDQLIEHSDF 345
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 144 bits (349), Expect = 3e-33
Identities = 90/293 (30%), Positives = 136/293 (46%), Gaps = 7/293 (2%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 79
IIAEAG NH G+ GA +KFQ E + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 80 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 139
E + LE ++ +++ + Y +++ I F ++A D L+ LKV IK+ SG+ +
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 140 LFLKYAASK----KIPLIISTGMVDKTAVKTIYDI-ISSDHK--QFCLLHCISAYPVPFE 192
LK A K + + +STGM + ++ DI I D + +LHC S YP P+
Sbjct: 125 PLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYPAPYN 184
Query: 193 DCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSL 252
N+ L+ +NTF VGYS EKHITLD++MKG DH SL
Sbjct: 185 AVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDHKASL 244
Query: 253 TPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEIL 305
P EF+ +V+++R E LG K + E ++S+ NKG++L
Sbjct: 245 NPQEFRSMVKEIRNCEEILGQEEKTLQDCERDTRYVARRSIRASEIINKGDVL 297
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 143 bits (347), Expect = 5e-33
Identities = 84/279 (30%), Positives = 131/279 (46%), Gaps = 10/279 (3%)
Query: 6 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKY 65
I ++ +G +P ++AE G NH D GA VKFQ T+++
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQSYV-----TEEF 63
Query: 66 LERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 125
++ NP++ K + E S+T +R+ + A++ G+ F ++ + + S L++LK
Sbjct: 64 ID--VHNPDA--KILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 126 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCI 184
VP IKI SGD N L A K+P+I+S+G D V + + + CLLHC+
Sbjct: 120 VPAIKIASGDITNKTLLLETAKSKLPVILSSGAADFFEVNRAISFLEKEGTDKLCLLHCV 179
Query: 185 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
S YP P E NL V++ +KN + PVG+S EKH TLD+++
Sbjct: 180 SLYPTPPEKANLKVVETFKNLYPFPVGFSDHTIGNIAASIAVSLGACMIEKHFTLDRNLD 239
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEI 283
G DH S P E + + + + G KK EI
Sbjct: 240 GPDHGISANPEELKTVCENALIAWKMKGNGEKKPWPEEI 278
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 139 bits (337), Expect = 9e-32
Identities = 65/113 (57%), Positives = 77/113 (68%)
Query: 2 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 61
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 62 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMD 114
+K LERPY + +SWGKTYGEHK HLEF+ QYREL RYA+EVGI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
Score = 107 bits (257), Expect = 4e-22
Identities = 54/147 (36%), Positives = 85/147 (57%), Gaps = 1/147 (0%)
Query: 200 QDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQ 258
++Y+ F D+P+GYSG E E+HITLDK+ KG+DH SL P E
Sbjct: 116 EEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELA 175
Query: 259 QLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIKVAEPK 318
+LVR VR++E +LG+P K+++ E+ C +KL KS+V +G IL + +KV EPK
Sbjct: 176 ELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPK 235
Query: 319 GLNALHLEDVIYKTLVYDKKEDEPLNE 345
G + +++ K ++ +ED+ + E
Sbjct: 236 GYPPEDIFNLVGKKVLVTVEEDDTIME 262
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 136 bits (330), Expect = 6e-31
Identities = 101/339 (29%), Positives = 145/339 (42%), Gaps = 11/339 (3%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
+I+AE G NH G G + VKFQ T +K + + G+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQ-TFKADKLISAIAPKAEYQIKNTGE 63
Query: 79 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 136
E LE Y L YA + + ++ D S DFL +LK KI SG+
Sbjct: 64 LESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGEL 123
Query: 137 NNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISSDHK---QFCLLHCISAYPVP 190
NL +L+ A IP +IISTGM +K I ++ +LHC + YP P
Sbjct: 124 LNLPYLEKIAKLPIPDKKIIISTGMATIDEIKQSVSIFINNKVPVGNITILHCNTEYPTP 183
Query: 191 FEDCNLTVLQDYKNTFDVP-VGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
FED NL + D K F +G+S EKH TLDKSM G DH+
Sbjct: 184 FEDVNLNAINDLKKHFPKNNIGFSDHSSGFYAAIAAVPYGITFIEKHFTLDKSMSGPDHL 243
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGD 309
S+ P E + L VR +E SLG+ K V SE +KS++ + KGE+ +
Sbjct: 244 ASIEPDELKHLCIGVRCVEKSLGSNSKVVTASERKNKIVARKSIIAKTEIKKGEVFSEKN 303
Query: 310 VKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
+ K G++ + +++ K D DE + +F
Sbjct: 304 ITTK-RPGNGISPMEWYNLLGKIAEQDFIPDELIIHSEF 341
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 136 bits (329), Expect = 8e-31
Identities = 94/330 (28%), Positives = 148/330 (44%), Gaps = 11/330 (3%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTK--KYLERPYDNPNSWG 77
+IAEAG NH G GA +KFQ T E L + NS+
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQ-TFKSESLASFSAPLAQYQKKSNSYK 63
Query: 78 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 137
KS LE +D + +F + E+GI F +S + FL++L + IKI SG+
Sbjct: 64 SQIDMLKS-LELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGEIT 122
Query: 138 NLLFL----KYAASKKIPLIISTGMVDKTAVKTIYDIISSDH--KQFCLLHCISAYPVPF 191
N + K+ + I +++STGM ++ ++ ++ ++HC+S+YP P
Sbjct: 123 NYALISEIGKFISEGNINVLLSTGMSSLGDIEEALSLLRFKETLERITIMHCVSSYPAPN 182
Query: 192 EDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
+D NL VL +N F GYS EKH+TLDK + G DH S
Sbjct: 183 KDLNLKVLSTLQNCFGCKTGYSDHSENIIAPIISIALGASAIEKHLTLDKDLPGPDHKAS 242
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVK 311
+TP F ++V D+R E LG K+ SEI ++S+ + KG ++ ++
Sbjct: 243 ITPKLFAKMVSDIRATEVMLGNSRKETKESEIENKLIARRSIRAFNNIQKGSLITKKNI- 301
Query: 312 IKVAEPKGLNALHLEDVIYKTLVYDKKEDE 341
I GL+ + ++ VI D K+ +
Sbjct: 302 IFQRPGNGLSPMEIDKVIGAVASKDYKDGD 331
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 135 bits (326), Expect = 2e-30
Identities = 95/305 (31%), Positives = 136/305 (44%), Gaps = 17/305 (5%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
++G + FIIAE G NH G+ GA VKFQ + +K Y
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMF-----YPEKLCSEIY 64
Query: 71 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
K E S ++L Y +G+ F + D S D ++NL IK
Sbjct: 65 R------KDEIEMLKKYVLSFENMKKLRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 131 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPV 189
+ SG+ ++ F+K AAS PLIISTG + + V + + I S ++ +LHC+S YP
Sbjct: 119 VASGELTHIPFIKKAASYNKPLIISTGASNLSDVERAVIAIKSVADEKISILHCVSTYPS 178
Query: 190 PFEDCNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDH 248
P E NL L+ + F D +G+S EKHITLDK++KG DH
Sbjct: 179 PDECLNLRALKTLEVAFNDCIIGFSDHSLGYTASNLAVALGASIIEKHITLDKNLKGPDH 238
Query: 249 VCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPG 308
S + EF +V D+R E LG KK C + + +S+V GE+L
Sbjct: 239 KASASQGEFVNMVYDIRKAEKMLGDGYKKPQA----CEEIIGRSIVAARDLEAGEVLRKE 294
Query: 309 DVKIK 313
D+ K
Sbjct: 295 DIDYK 299
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 134 bits (325), Expect = 2e-30
Identities = 108/322 (33%), Positives = 146/322 (45%), Gaps = 13/322 (4%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ--KTCLGEKFTKKYLERPYDNP 73
N FIIAEAG NH GD G VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENT 62
Query: 74 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 133
+T E LE S + EL Y + GI F ++ + S FL L+ F KIGS
Sbjct: 63 QR-EETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 134 GDSNNLLFLKYAASKKIPLIISTGM----VDKTAVKTIYDI-ISSDHKQFCLLHCISAYP 188
G+ N FL++ AS P+I+STGM + AV T+ D +S D +LH + YP
Sbjct: 121 GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGLSLD--MITVLHATTDYP 178
Query: 189 VPFEDCNLTVLQDYKNTFD-VPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTD 247
ED NL ++ + F + VGYS EKH TLDK+M G D
Sbjct: 179 TAPEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPD 238
Query: 248 HVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYP 307
H SL P E +V +R IE +LG K +E + ++KSLV G G I+
Sbjct: 239 HKASLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICA 298
Query: 308 GDVKIKVAEPKGLNALHLEDVI 329
++IK G++ ++V+
Sbjct: 299 DMLEIK-RPGNGISPTRWDEVV 319
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 134 bits (325), Expect = 2e-30
Identities = 98/325 (30%), Positives = 147/325 (45%), Gaps = 33/325 (10%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 79
IIAEAG NH GD GA VKFQ T+K + Y N G+
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKNL-GRE 62
Query: 80 YGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 136
+ LE S + EL Y E+GI F ++A D S +FLVN L + +K+ SG+
Sbjct: 63 ESQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEI 122
Query: 137 NNL-LFLKYAASKKIPLIISTGMVDKTAVKTI-----YDIISSDHKQ------------- 177
N L LK+A + LI+STGM ++++ Y ++ KQ
Sbjct: 123 TNAPLVLKHAQTG-CDLIVSTGMATMAEIESVLGVIAYGYLNPHAKQATRADFETAYASE 181
Query: 178 ---------FCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXX 228
+LHC + YP P E+ NL + TF + +GYS
Sbjct: 182 SGQQILREKVTVLHCTTEYPAPMEEINLNAMNTIGTTFRLQIGYSDHSRGITIPIAAVAK 241
Query: 229 XXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDK 288
EKH TLD++++G DH SL P E ++V +R +E ++G +K+ SE+ +
Sbjct: 242 GATIIEKHFTLDRNLEGPDHKASLEPDELAEMVTAIRDVEKAMGDGVKRPTVSEVNNKNI 301
Query: 289 LQKSLVMGSTKNKGEILYPGDVKIK 313
+KSLV + KG+++ D+ +K
Sbjct: 302 ARKSLVTVNPLKKGQVITADDIAVK 326
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 134 bits (323), Expect = 4e-30
Identities = 101/340 (29%), Positives = 154/340 (45%), Gaps = 12/340 (3%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
+IG ++ ++I E NH G G +K Q T + T ++RP
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLD-VDRPE 75
Query: 71 DNPNS--W-GKTYGE--HKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 125
+ W G+T E ++H F + +F A++ G+ +S D + D L +L
Sbjct: 76 FKIHGGLWDGRTLYELYEEAHTPFE--WHAAIFERARQRGVTIFSSPFDETAVDLLDSLG 133
Query: 126 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDI-ISSDHKQFCLLHCI 184
P KI S ++ +L +KYAA+K PLIISTGM + T ++T D +S+ LLHC+
Sbjct: 134 APAFKIASFEAVDLPLIKYAAAKGKPLIISTGMANLTEMQTALDTALSAGAPGVLLLHCV 193
Query: 185 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
S+YP F D N+ + D F P+G S EKH TL ++
Sbjct: 194 SSYPATFADANVRTVPDMAARFGCPIGLSDHTPGTAASVAAVSLGACAVEKHFTLARADG 253
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
G D SL P+EF+ LV D + A+LG V+ SE + ++SL + + GE
Sbjct: 254 GPDAAFSLEPAEFKALVDDTKNAWAALGRAHYDVLGSEATSL-LFRRSLYVTADVKAGEP 312
Query: 305 LYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLN 344
L +V+ V GL L+ V+ D EPL+
Sbjct: 313 LTRANVR-SVRPGNGLPPADLDKVLAGKATRDLARGEPLD 351
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 133 bits (322), Expect = 6e-30
Identities = 95/323 (29%), Positives = 140/323 (43%), Gaps = 29/323 (8%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK- 78
IIAEAG NH GD GA VKFQ T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 137
+ S LE S + +L ++ + +GI F ++A D S DFLVN L + +K+ SG+
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 138 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-----SDH----------------- 175
N + A LI+STGM ++ +I+ +DH
Sbjct: 124 NAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFGYTAADHVAPSVLAFQQAYASNEG 183
Query: 176 -----KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXX 230
++ +LHC + YP P + NL + FD+P GYS
Sbjct: 184 QKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVARGA 243
Query: 231 XXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQ 290
EKH TLDK+M+G DH SL P E +V+ +R +E +LG+ +K SE+ +
Sbjct: 244 VLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKAVAR 303
Query: 291 KSLVMGSTKNKGEILYPGDVKIK 313
KSLV G+ +V IK
Sbjct: 304 KSLVASQAIQAGDAFSADNVTIK 326
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 132 bits (318), Expect = 2e-29
Identities = 81/264 (30%), Positives = 122/264 (46%), Gaps = 13/264 (4%)
Query: 9 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 68
+I+IGGNNP FIIAEAG NH GD A+ +KFQ E+F +
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAV 68
Query: 69 PYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 128
P +GK ++ L +Q+ ILF A+ D+ + + L + V
Sbjct: 69 NLVKPAEFGK-------------KEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 129 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP 188
+KI S D N+ L+ AA + +I+S G + ++T I F LLHC+S+YP
Sbjct: 116 LKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYP 175
Query: 189 VPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDH 248
+ D NL+ +Q K+ ++ P+GYS EKH T+D++++G D
Sbjct: 176 MNEIDANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDW 235
Query: 249 VCSLTPSEFQQLVRDVRVIEASLG 272
S P E +LV + I LG
Sbjct: 236 EISAEPKELAKLVTETERIRKILG 259
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 132 bits (318), Expect = 2e-29
Identities = 87/298 (29%), Positives = 134/298 (44%), Gaps = 5/298 (1%)
Query: 17 PCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSW 76
P +IIAE G N G VK Q T E + K +D N+
Sbjct: 10 PIYIIAEIGGNFT-TFEEAKALVDAAASCGVDAVKLQ-TYRAETVSSK--SAIFDMENTG 65
Query: 77 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 136
+ E E + +R++F Y + G+ + ++ D L L V KIGS D+
Sbjct: 66 IASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDA 125
Query: 137 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFEDCN 195
N+ FL+Y A+K P++++TGM V+ D+I + + + LLH +++YP E N
Sbjct: 126 VNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTHPEHVN 185
Query: 196 LTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPS 255
L +Q F++PVGYS EKH T DK+ +G DH+ S P+
Sbjct: 186 LLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHILSADPA 245
Query: 256 EFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIK 313
E + +V VR +EA +G+ +K SE +KS+V G L D+ +K
Sbjct: 246 EMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDIAVK 303
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 131 bits (317), Expect = 2e-29
Identities = 95/339 (28%), Positives = 151/339 (44%), Gaps = 11/339 (3%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
+I+AE G NH GD G VKFQ T ++ KY + G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 79 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 136
E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGEL 123
Query: 137 NNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISSDH---KQFCLLHCISAYPVP 190
NL +L+ + I +++STGM +K ++++ + ++ +LHC + YP P
Sbjct: 124 LNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMAPEKITILHCNTEYPTP 183
Query: 191 FEDCNLTVLQDYKNTFD-VPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
+ED NL + KN F VG+S EKH TL+K+ +G DH
Sbjct: 184 YEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKNFEGPDHK 243
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGD 309
S+TP E + L +R +E LG+ K V SE +KS+V KGEI +
Sbjct: 244 ASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYTIDN 303
Query: 310 VKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
+ K G++ ++ D++ K + ED+ ++ F
Sbjct: 304 ITTK-RPGNGISPMYWYDILGKKAEKNFDEDQLISHSGF 341
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 130 bits (315), Expect = 4e-29
Identities = 100/344 (29%), Positives = 158/344 (45%), Gaps = 19/344 (5%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFT----KKYL 66
+IG FIIAE NH D GA +K Q T + T +Y
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQ-TYTPDTITFDSDNEYF 69
Query: 67 ERPYDNPNSWGKTYGEHKSHLE-FSDTQYR-ELFRYAQEVGILFTASAMDMVSFDFLVNL 124
+ W T HK + E ++ Q++ +L A+E G++ +S D S DFL +
Sbjct: 70 Q--IKQGTIWDGTT-LHKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKM 126
Query: 125 KVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ----FCL 180
+VP K+ S + ++ F++Y ASK P+I+STG+ + + IY+ +++ +Q L
Sbjct: 127 EVPAYKVASFELTDIPFIEYIASKGKPVIMSTGIAE---MGEIYEAVAACRRQGNENVIL 183
Query: 181 LHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLD 240
L C S+YP P ED NL + + + F+ VG S EKH TL
Sbjct: 184 LKCSSSYPSPLEDINLKTIPNMREAFNCSVGLSDHTMGYSVATAAVALGATVIEKHFTLK 243
Query: 241 KSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKN 300
+S G D S+ P EF +V+ +R +E +LG + +T + + +SL +
Sbjct: 244 RSDGGPDSAFSMEPEEFSAMVKSIREVEKALG-KVTYELTEKQKNSRQHSRSLFVVKDIK 302
Query: 301 KGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLN 344
KGE +VK + GL ++E+VI K D K+ PL+
Sbjct: 303 KGETFTKENVK-SIRPAFGLKTKYIEEVIGKKARVDVKKGTPLD 345
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 130 bits (315), Expect = 4e-29
Identities = 92/336 (27%), Positives = 145/336 (43%), Gaps = 5/336 (1%)
Query: 18 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG 77
C +I E G NH G +K Q+ ++ + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 78 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 136
++ + LE D + F Y ++ G+ F +A D S DFL + L +KI S +
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPSPEV 135
Query: 137 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH--KQFCLLHCISAYPVPFEDC 194
+N L++ A + L++STG V D ++++ ++ L+HC+S YP P E
Sbjct: 136 SNKPLLQHMARRFDGLLLSTGASYLGEVANAIDWLAAEAGPRELALMHCLSEYPAPVEQA 195
Query: 195 NLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTP 254
NL + + F VPVGYS EKH TLDK++ G DH SL
Sbjct: 196 NLRAMASMRAAFKVPVGYSDHTPGQVAAVVAVGLGAAMIEKHYTLDKNLPGPDHQASLDI 255
Query: 255 SEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMG-STKNKGEILYPGDVKIK 313
E + V VR ASLG IK+ +EI ++KS+V G + + +K
Sbjct: 256 PELRAFVTAVRQASASLGDGIKRPAPAEIDNRPLIRKSVVCAVPAIEAGTAVTAAMLGVK 315
Query: 314 VAEPKG-LNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
+G + +E ++ +L +DK+ DE + DF
Sbjct: 316 RPWTRGAVEPFEIEKILGLSLRHDKQYDEAILWSDF 351
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 130 bits (314), Expect = 5e-29
Identities = 106/338 (31%), Positives = 144/338 (42%), Gaps = 16/338 (4%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE---KFTKK--YLERPYDNP 73
FIIAEAG NH GD A VKFQ GE +F K YLE +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 74 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIG 132
S Y E L +REL + + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 133 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPF 191
S + + +L+ P I+STG+ V K + + LLHC S YP P
Sbjct: 130 STEVTHPQYLEAIGRTGRPAILSTGLSTLGEVEKAVAALRRGGVGPLALLHCTSEYPAPD 189
Query: 192 EDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
NL + F +PVG S EKH TLD+S+ G DH S
Sbjct: 190 SQMNLRAMTTLGRAFGLPVGLSDHSLGGEAALAAIALGAVIIEKHFTLDRSLPGPDHQAS 249
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVK 311
L P V +R +EA LG IK+ +E+ ++ +++ +V G IL D
Sbjct: 250 LDPQGLAAFVAAIRRVEAMLGDQIKRPTATELANMNGIRRGVVAARNLAAGTIL---DTT 306
Query: 312 IKVAEPK--GLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+ V + G+ L+ + TL D EDEPL+ D
Sbjct: 307 MLVCKRPGGGIEPEDLDRLAGFTLRRDLAEDEPLSWDD 344
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 130 bits (314), Expect = 5e-29
Identities = 87/290 (30%), Positives = 141/290 (48%), Gaps = 16/290 (5%)
Query: 19 FIIAEAGQNH-----QGDXX---XXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
FI+AEAG N+ +G+ GA +KFQ T E+ KY +
Sbjct: 19 FIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-TYKAERIASKYSPAYW 77
Query: 71 DNPNSWGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 129
D K+ Y K +F + +Y+EL YA ILF ++ D + DFL L +P
Sbjct: 78 DVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFDNEAVDFLDKL-MPVF 136
Query: 130 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 188
KI S D N+ F+ Y A K+ P+ +STG +K + I S+ + + +LHCI YP
Sbjct: 137 KISSSDITNIPFISYVARKRKPIFLSTGASTIEEIKEAVNAIESEGNDKIVILHCILNYP 196
Query: 189 VPFEDCNLTVLQDYKNTFD-VPVGYSGQ---EXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
+ED NL +++ + F VGYS + EKH TLDK+++
Sbjct: 197 TKYEDANLGMIKHIQKVFPGYLVGYSDHTLPDSCMLVLTTAVLLGAKVIEKHFTLDKTLQ 256
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLV 294
G DH S+ P + ++++++V+++ +G K+ + SE+ I ++S+V
Sbjct: 257 GNDHYHSMDPHDLEKIIKNVKLLGKIIGEHEKRPLESELIAIKYARRSIV 306
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 129 bits (311), Expect = 1e-28
Identities = 93/349 (26%), Positives = 150/349 (42%), Gaps = 7/349 (2%)
Query: 1 MVEVKITDDIR-IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE 59
M + IT D R IG +IIAE NH+G G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 60 KFTKKYLERPYD-NPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 117
T ++ + N W G+T + ++ LF +A++ + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 118 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHK 176
+ L + + P KI S + N++ + AA P+++STG+ ++ + +++
Sbjct: 120 IELLESCECPAYKISSFEINDIGLIMAAAKTGKPIVMSTGLATLAEIEEAVEAVANAGGT 179
Query: 177 QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKH 236
Q LLHCIS YP P EDCNL + D F+ P+G S EKH
Sbjct: 180 QLALLHCISGYPTPIEDCNLKTVADLCQRFNFPIGLSDHTTDILASVTSVALGASIIEKH 239
Query: 237 ITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMG 296
TLDK+ G D SL P EF L ++ + ++LG + SE D ++S+ +
Sbjct: 240 FTLDKTDGGVDAAFSLEPDEFGLLKKETQRAHSALGYAGYDIKPSEAGGRD-FRRSVYVA 298
Query: 297 STKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNE 345
KGE+ +V+ V GL+ +L +I + D P+ E
Sbjct: 299 DDIRKGELFTASNVR-SVRPGLGLHTRYLPQIIGQKSSQDIAFGSPMKE 346
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 127 bits (307), Expect = 4e-28
Identities = 86/296 (29%), Positives = 121/296 (40%), Gaps = 9/296 (3%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
F+IAEAG NH G GA VKFQ E T + Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 138
T E LE D + L R+ E GI F ++ + D L+ L + IKI SG+ N
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASGEIVN 131
Query: 139 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK---------QFCLLHCISAYPV 189
+ A P+I+STGM + V D I + +LHC S YP
Sbjct: 132 KPLIDKVAGSGRPIILSTGMAEMAEVVRAVDWIRTAQSAAGIAMSPGDLVVLHCTSEYPA 191
Query: 190 PFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
P NL + DVPVGYS EKH T + G DH
Sbjct: 192 PAASVNLRAMDTLAAALDVPVGYSDHSLGIEIAVAAVARGAAVIEKHFTENSRDHGPDHA 251
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEIL 305
SL P++ + +V +R +E +LG +K+ E+P +++S + N+G+ L
Sbjct: 252 ASLEPAQLRAMVDAIRNVEVALGDGVKRPAPLELPTRALVRRSAFALTDINRGDRL 307
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 126 bits (305), Expect = 6e-28
Identities = 101/359 (28%), Positives = 153/359 (42%), Gaps = 29/359 (8%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 75
N FIIAEAG NH G GA VKFQ G + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 76 W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGS 133
++ + LE S + +L ++ ++ GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 134 GDSNNLLFLKYAASKKIPLIISTGM-------------------VDKTAVKTIY-DIISS 173
G+ N FL A +P+I+STGM + +T +T + + +S
Sbjct: 122 GELTNAPFLLKIAGYGLPVIVSTGMSTLGEAEMALGVLAFGFLGLSETPSETAFRNAFAS 181
Query: 174 DHKQFCL------LHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXX 227
D Q L L C + YP PF NL + F +PVG S
Sbjct: 182 DAGQAVLREKVTILQCTTEYPAPFAQVNLKAMDTLGAAFGLPVGLSDHTPGYAIPIAAVA 241
Query: 228 XXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCID 287
EKH TLD+++ G DH+ SL P E + +V +R + ++G K+ EI
Sbjct: 242 RGATLIEKHFTLDRNLPGPDHMASLEPHELKAMVEGIRQVTVAIGDGCKRPSADEIGNRT 301
Query: 288 KLQKSLVMGSTKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEG 346
++SLV + +GEI ++ K G++ D I K D + DE L+ G
Sbjct: 302 IARRSLVAATAVKRGEIWTESNLTCK-RPGDGVSPYRFWDFIGKPATRDYRADEKLDAG 359
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 124 bits (300), Expect = 3e-27
Identities = 97/345 (28%), Positives = 146/345 (42%), Gaps = 9/345 (2%)
Query: 1 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 60
M E+ I D IG N+P ++IAEAG +H GA +KFQ E
Sbjct: 1 MTELHI-DGRAIGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQTYTADEL 59
Query: 61 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 120
T+ Y + + + S T+YR LF YA+E+GI ++ D S D
Sbjct: 60 VTR--WAPLYWTDARFETQHQVFSTKRGLSPTEYRSLFDYARELGITPLSTPFDPASVDL 117
Query: 121 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCL 180
L L + K+ S D + L+ A K P+++STG V++ +++ S+ L
Sbjct: 118 LDGLGMAAFKVASADITHRPLLQDIAGKGKPVLLSTGAASMAEVRSALEVLESEGVPVAL 177
Query: 181 LHCISAYPVPFEDCNLTVLQDYKNTFDVPV-GYSGQ---EXXXXXXXXXXXXXXXXXEKH 236
LHC AYP P + NL+ L F V GYS EKH
Sbjct: 178 LHCSLAYPTPVDQANLSRLGLLAEQFPGRVLGYSDHTPPRDSALPCPASVLLGARVIEKH 237
Query: 237 ITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMG 296
+L++ + G DH S+ P +LVRD R A + P ++ +E + ++S+V
Sbjct: 238 FSLNRHLAGDDHYHSVDPDGLARLVRDCRDAWA-MSRPAAEITAAEESARTQARRSVVAA 296
Query: 297 STKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDE 341
+ G L G + K G+ ED+I + L D DE
Sbjct: 297 TDLPAGTTLAAGHLAYK-RPGTGVPPTQAEDLIGRRLAVDLAHDE 340
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 124 bits (298), Expect = 5e-27
Identities = 84/281 (29%), Positives = 134/281 (47%), Gaps = 10/281 (3%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXX-GASCVKFQKTCLGEKFTKKYLERPYDNP-NSWG 77
+IAE G NH+G+ VKFQK E T + P+ P NS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 78 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 137
KTYGEH+ LEF+ Q+++L ++ + G++++ S D+ + +V++ IKI S +
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 138 NLLFLKYAASKKIPLI-ISTGMV---DKTAVKTIYDIISSDHKQFCLLHCISAYPVPFED 193
L+Y + I +S GM ++ V T ++ K + C S YPVPFED
Sbjct: 126 KFDMLEYLCKEYDGEIHLSFGMTTNEEEEKVVTFFE-DRGRGKDLIIYSCTSGYPVPFED 184
Query: 194 CNLTVLQDYKNTFDVPV---GYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVC 250
L + + F+ V G+SG E+H TLD++ KGTDH
Sbjct: 185 ICLKEILRIRAKFEKRVKGIGFSGHHLGIAADIAALAYGAKYFERHFTLDRTWKGTDHAA 244
Query: 251 SLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQK 291
SL P ++L RD+R + +L K+++ E +KL++
Sbjct: 245 SLEPDGMRRLARDLRNVSKALTYKQKEILDIEEIQRNKLKR 285
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 123 bits (297), Expect = 6e-27
Identities = 92/330 (27%), Positives = 139/330 (42%), Gaps = 8/330 (2%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
FIIAE NH D G +K Q T + T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 79 TYGEHKSHLEF-SDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
G++ L + T Y + LF YA+ +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHKQFCLLHCISAYPVPFED 193
+ +L ++ A P+I+STGM K+ ++ ++ + LL C S YP ED
Sbjct: 130 ELTDLPLIEAVARTGKPMIMSTGMATKSEIEEAVSLVRLIGDNEITLLKCTSTYPAKIED 189
Query: 194 CNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLT 253
NL L D ++F VG S EKH LD+S G D S+
Sbjct: 190 SNLITLSDLASSFHCKVGLSDHTQGIAAAVTATALGASVIEKHFVLDRSAGGVDAAFSME 249
Query: 254 PSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIK 313
P E LV R +SLG + T+ K ++S+ + G+ L +++I
Sbjct: 250 PDEMSLLVETCRQASSSLGA-VTYGGTAAEQDFKKYRRSIYIAQDCKAGDQLDSSNIQI- 307
Query: 314 VAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
+ GL H DV+ +TLV D K+ E L
Sbjct: 308 IRPSLGLAPKHWSDVLGQTLVQDVKKGEAL 337
>UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum
gryphiswaldense|Rep: NeuB - Magnetospirillum
gryphiswaldense
Length = 337
Score = 122 bits (294), Expect = 1e-26
Identities = 72/246 (29%), Positives = 119/246 (48%), Gaps = 2/246 (0%)
Query: 88 EFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAAS 147
E + + EL +E+G+ + ++ + D L K GS D N FL+ A
Sbjct: 77 ELTRDDHVELIDLCRELGVAWMSTPSHVSDLDLLEPFDPIAYKTGSDDLTNTRFLRQIAE 136
Query: 148 KKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTF 206
K P+++STGM ++ D+I+ + + + LLHC+ +YP ED NL ++ + F
Sbjct: 137 KGRPMVVSTGMCTLAEIERAVDVITRTGNTELILLHCVVSYPAKAEDANLRAIETLQRAF 196
Query: 207 DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRV 266
+PVG S EKH TLD ++K DH SL P+ F+ LV VR+
Sbjct: 197 GLPVGLSDHTIDEFTSVLATQMGACIIEKHFTLDHALKLPDHQASLDPAAFKLLVDRVRL 256
Query: 267 IEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIKVAEPKGLNALHLE 326
+ A++G K+++ +E +KSL G+I+ D+ I+ G++ HL+
Sbjct: 257 VSAAMGDGTKRILPTEEKWRAAARKSLYAARDIAAGQIISDDDIAIR-RPADGIHPHHLD 315
Query: 327 DVIYKT 332
VI +T
Sbjct: 316 LVIGRT 321
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 121 bits (292), Expect = 2e-26
Identities = 92/352 (26%), Positives = 162/352 (46%), Gaps = 14/352 (3%)
Query: 4 VKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEK 60
+++ + I G +P ++IAE G NH+G GA KFQ L K
Sbjct: 15 IQLGNKIIAGFFDP-YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASK 73
Query: 61 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 120
+ Y +R + S + + ++ S F +Y L ++ Q VGI F ++ D+ + +
Sbjct: 74 NSPSYWDRTQEPTASQFELFKKYDS---FGWKEYEILAKHCQSVGIDFLSTPFDLEAVEH 130
Query: 121 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFC 179
L + ++PFIK+ S D ++ L+ A P+I+STG + + ++ ++ +
Sbjct: 131 LAS-QMPFIKVASADITSVPLLRSVAKYSKPVILSTGSSTIPEIDFAMRELHANGANEII 189
Query: 180 LLHCISAYPVPFEDCNLTVLQDYKNTFDVP-VGYSGQ---EXXXXXXXXXXXXXXXXXEK 235
LLHCI YP E+ NL ++QD + F VGYS + EK
Sbjct: 190 LLHCILNYPTKPENANLGMIQDLQRIFPHHWVGYSDHTPPDLEMKSLITATLFGSVVLEK 249
Query: 236 HITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVM 295
H T DK++ G DH ++ + ++ R ++ E+ +G+ K + SE ++S+V+
Sbjct: 250 HFTHDKTLPGNDHYHAMDKEDLKRFKRKLKEFESLIGSSEKAPLQSEELSRKNARRSIVL 309
Query: 296 GSTKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+KG + D+ K G++ + +DVI + + D ED LN D
Sbjct: 310 SKNLSKGSKIKEQDITFK-RPAHGISPIFWDDVIGRVINRDLLEDHILNWED 360
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 121 bits (292), Expect = 2e-26
Identities = 93/310 (30%), Positives = 138/310 (44%), Gaps = 25/310 (8%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG-K 78
IIAEAG NH G GA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 137
+ + LE S+ + L + ++ GI F +S D +S +FL++ L + IK+GSG+
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGELT 124
Query: 138 NLLFLKYAASKKIPLIISTGMVD--KTA--------------VKTIYDIISSDH------ 175
N L A + +I+STGM D +TA T +I ++ H
Sbjct: 125 NGPLLLQAGASGRNIILSTGMADLAETAQAVGVIGCGANGVLAPTESEIQAAAHCPSPDL 184
Query: 176 -KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXE 234
++ LLHC + YP P + NL ++ + TF + VG+S E
Sbjct: 185 IRRLTLLHCTTEYPAPMDQVNLRAMETLRQTFGLRVGFSDHTPGITAAVAAAALGASVIE 244
Query: 235 KHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLV 294
KH+TLD+ + G DH SL P E + LV VR + A+LG K + SE D +KSL
Sbjct: 245 KHLTLDRGLPGPDHKASLEPLEMKALVDSVRQVTAALGDGRKVPMPSERGNADIARKSLA 304
Query: 295 MGSTKNKGEI 304
+ + +GE+
Sbjct: 305 VAAPIGRGEV 314
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 121 bits (292), Expect = 2e-26
Identities = 82/301 (27%), Positives = 135/301 (44%), Gaps = 5/301 (1%)
Query: 11 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 70
+IG +P +IAE G NH GD G VK Q + ++ T++ R
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEE--ARQI 64
Query: 71 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
PN+ + E S + EL RY + +G+++ ++ + DFL +L VP K
Sbjct: 65 FPPNA-DVSIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 131 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVP 190
IGSG+++NL +++ A P+I+STGM +++ I+ + LL C + YP P
Sbjct: 124 IGSGEADNLPLIRHIARMGKPVIMSTGMQSIESIRASVAILDGAGVDYALLECTNLYPSP 183
Query: 191 FEDCNLTVLQDYKNTFD-VPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHV 249
E +L + D KN F +G+S E+H T + KG D +
Sbjct: 184 PEIVSLQGVTDLKNAFPRAVIGFSDHSIGPNMALASVALGACILERHYTDSRYRKGPDII 243
Query: 250 CSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGD 309
S+ P+E + L+ R I +L P K+ +E P + S+V G ++ D
Sbjct: 244 NSMDPAELRYLIDRSREIHTALRNP-KQRTAAEEPVYRFARASVVADRDLPAGHVITEAD 302
Query: 310 V 310
+
Sbjct: 303 I 303
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 120 bits (288), Expect = 7e-26
Identities = 86/318 (27%), Positives = 134/318 (42%), Gaps = 3/318 (0%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 79
+IAE GQ H+G G VKFQ + E LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQ-VHIAEA-ESSILEPFRIKFSEQDKT 60
Query: 80 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 139
++ +EFS +++ + + ++ + F AS + D L + V KIGSG+ NN
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 140 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 199
L L+ A +IIS+GM + + F LL C ++YP + L V+
Sbjct: 121 LLLEKIAKTGKQVIISSGMSSFDELDATVSFLRERKISFSLLQCTTSYPTTPANYGLNVI 180
Query: 200 QDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQ 259
Q+ K + V VGYS E H + G D SL SE +
Sbjct: 181 QELKQRYKVKVGYSDHSSKIETCIAATAMGAEILEFHAVFSRKSFGPDVSSSLELSEIRM 240
Query: 260 LVRDVRVIEASLGTPIKKVVTSEIPCIDKL-QKSLVMGSTKNKGEILYPGDVKIKVAEPK 318
LV +R I +L P+ K S+ + ++ +KSL + KGEI+ ++ K +
Sbjct: 241 LVAAIRNISTALNEPVSKADNSKYSGLKQIFEKSLAVNKDLRKGEIIKFEHLEAKKPKEY 300
Query: 319 GLNALHLEDVIYKTLVYD 336
G++A + VI K + D
Sbjct: 301 GIDASQFDQVIGKKIAND 318
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 114 bits (275), Expect = 3e-24
Identities = 91/346 (26%), Positives = 144/346 (41%), Gaps = 9/346 (2%)
Query: 6 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEKFT 62
I + I ++P + IA+ NH GD GA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 63 KKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV 122
K L + ++W K+ E + E EL ++ I F S D D++
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADYID 130
Query: 123 NLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLH 182
VP KIGSGD L++ A K P ++TG + V + + + L+
Sbjct: 131 QF-VPAHKIGSGDITWHAMLEHIAKKNKPYFLATGASELADVVAAVEACLKINPKLVLMQ 189
Query: 183 CISAYPVPFED---CNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHIT 238
C + Y E+ NL VL+ Y+ F ++ +G S EKH T
Sbjct: 190 CNTNYTASLENFAYINLNVLKTYRTLFPELVLGLSDHTPGHSTVLGAVALGARVIEKHFT 249
Query: 239 LDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGST 298
D G DH S+ P ++++V R +EA+LG+PIKKV +E + ++S+ +
Sbjct: 250 DDNQRNGPDHKFSMNPVTWKEMVDRTRELEAALGSPIKKVEANEAETVVLQRRSVRLTRD 309
Query: 299 KNKGEILYPGDVK-IKVAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
GE+L D++ ++ A L+DVI +L D + E L
Sbjct: 310 MKAGEVLVEADLECLRPAPVDAFLPYQLQDVIGLSLKQDMVKGEHL 355
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 113 bits (273), Expect = 5e-24
Identities = 94/323 (29%), Positives = 136/323 (42%), Gaps = 25/323 (7%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 74
N+ F+IAEAG NH GD GA +KFQ T + E +
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQ-TFIPEALVTTTARKAGYQKT 61
Query: 75 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
+ ++ L + EL YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIY---------DIISSDHKQFC-- 179
+ NL FL A+ + LI+STGM + A+ +IY IS+ K +
Sbjct: 122 ELTNLPFLIEHAALQQDLILSTGMATLGEIELALASIYWGRVQKDYPPSISALRKAWIER 181
Query: 180 ---------LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXX 230
LLHC S+YP + N+ + F +PVGYS
Sbjct: 182 DPSVALNTTLLHCTSSYPAAPDTVNIRAMTTLAEIFQLPVGYSDHTQGTTASIMAIAKGA 241
Query: 231 XXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQ 290
EKH+TLDK++ G DH S++P+E + V R + LG K+ TSE+ +
Sbjct: 242 RVIEKHVTLDKTLSGPDHRASMSPAELHEWVAVCREAVSMLGDGNKQPQTSEMDVKQAAR 301
Query: 291 KSLVMGSTKNKGEILYPGDVKIK 313
KSLV + KG++ ++ IK
Sbjct: 302 KSLVAKTAIRKGDVFTSENLAIK 324
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 113 bits (271), Expect = 9e-24
Identities = 87/332 (26%), Positives = 143/332 (43%), Gaps = 6/332 (1%)
Query: 8 DDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLE 67
D I + +IIAE NH GD G S +K Q T + T L+
Sbjct: 4 DQTNINEAHKPYIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQ 62
Query: 68 RPYDNPNS-W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 125
+ + W G++ E + + ELF +A+ G+ ++ D + D L +L
Sbjct: 63 DDFIVKDGLWAGRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLN 122
Query: 126 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCI 184
P KI S + +L +KY ASK P+++STGM +T + + + + ++ + L HCI
Sbjct: 123 TPAYKIASFEIVDLPLVKYIASKNKPILMSTGMASQTEIEEAVTSVRANGDCELLLFHCI 182
Query: 185 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
S+YP ED NL L + F V VG S EKH LD +
Sbjct: 183 SSYPAVTEDSNLRNLNWLREKFGVEVGLSDHTTNNIAALTAIGMGAVAVEKHFKLDTNDC 242
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
G D SL+ E Q LV + + G+ K SE + ++SL ++ KG+
Sbjct: 243 GPDSSFSLSVEELQSLVIECNEAWTAKGSFGFKRAHSEAQNM-VFRRSLYFVNSLKKGQS 301
Query: 305 LYPGDVKIKVAEPKGLNALHLEDVIYKTLVYD 336
+ D++ ++ GL + + ++ + + D
Sbjct: 302 ISRNDIR-RIRPGYGLPPKYFDSILGREVTKD 332
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 113 bits (271), Expect = 9e-24
Identities = 80/277 (28%), Positives = 122/277 (44%), Gaps = 9/277 (3%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
+G + P FIIAEAG NH G GA VKFQ + + Y + P
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQMF----QADRMYQKDPGL 66
Query: 72 NPNSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 129
+ GK +E L Y +E ++F ++ D S D L +
Sbjct: 67 YKTAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAF 126
Query: 130 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 188
KI S + N+L LKY A P+I ST + + V + I ++ + Q ++HC++ YP
Sbjct: 127 KIASYEINHLPLLKYVARLNRPMIFSTAGAEISDVHEAWRTIRAEGNNQIAIMHCVAKYP 186
Query: 189 VPFEDCNLTVLQDYKNTF-DVPVGYSGQ-EXXXXXXXXXXXXXXXXXEKHITLDKSMKGT 246
P E NL+V+ F + +G+S E EKH T+DK++ G
Sbjct: 187 APPEYSNLSVIPMLAAAFPEAVIGFSDHSEHPTEAPCAAVRLGAKLIEKHFTIDKNLPGA 246
Query: 247 DHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEI 283
DH +L P E +++V +R EA L I K V+ ++
Sbjct: 247 DHSFALNPDELKEMVDGIRKTEAELKQGITKPVSEKL 283
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 111 bits (267), Expect = 3e-23
Identities = 74/271 (27%), Positives = 117/271 (43%), Gaps = 13/271 (4%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 74
+N ++IAE G NH GD G VKFQ T L EK P ++P
Sbjct: 12 DNKVYVIAEIGLNHGGDMNTAKRLIDSASKTGVDAVKFQ-TYLTEK------RVPKNSP- 63
Query: 75 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
+ E ++EL Y + I F ++ D S DFL ++ K+ S
Sbjct: 64 -----IFDILKKCELPFEVFKELKDYTETYNIEFFSTPFDEESVDFLESVNCALYKVASF 118
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 194
D N L A K +I+S GM + + ++ + I+ + + ++HC+SAYP ED
Sbjct: 119 DVVNYKLLSKIADTKKTIIMSVGMANLSEIEGAFKILKNKTDKLAIMHCVSAYPTKEEDA 178
Query: 195 NLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTP 254
NL+ + K+ FD +G S EKH +D+ M D S+T
Sbjct: 179 NLSAIYTLKDKFDCIIGQSDHTAGVTVPLYAIAAGAQIIEKHYKIDEDMNCVDAPVSITE 238
Query: 255 SEFQQLVRDVRVIEASLGTPIKKVVTSEIPC 285
+ + L++++R +E+ LG V +E C
Sbjct: 239 EQMRNLIKEIRRLESILGNGEFGVRAAEAGC 269
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 110 bits (265), Expect = 5e-23
Identities = 87/340 (25%), Positives = 139/340 (40%), Gaps = 8/340 (2%)
Query: 2 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 61
++V D IG P F+IAE NH GAS +K Q T +
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 62 TKKYLERPY---DNPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 117
T + D N W G++ + S ++ LF YA+ +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 118 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-K 176
++L L VP KI S ++N+ L A P+I+STGM + + ++ +
Sbjct: 120 VEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCR 179
Query: 177 QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKH 236
LL C S YP D NL+ + FD VG S EKH
Sbjct: 180 DLILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKH 239
Query: 237 ITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMG 296
+D++ G D SL P EF+ LV + +LG EI K ++SL +
Sbjct: 240 FVIDRNEGGVDSEFSLEPREFKSLVMETERARVALGRVHYGCTAKEI-ASRKYRRSLYVS 298
Query: 297 STKNKGEILYPGDVKIKVAEPKGLNALHLEDVIYKTLVYD 336
+ G+IL +++ V G+ +L ++ K + D
Sbjct: 299 RDMSAGDILTVDNLR-SVRPGLGIAPKYLHQLLGKAVKQD 337
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 110 bits (264), Expect = 6e-23
Identities = 85/337 (25%), Positives = 136/337 (40%), Gaps = 5/337 (1%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
IG ++ ++AE G NH+G GA +K Q + ++ + +
Sbjct: 18 IGYDHDPVVVAEIGINHEGSLETAYEMVDAAVSAGAEIIKHQTHVVEDEMSA---DAKKV 74
Query: 72 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
P + + E ++ +L Y + G +F ++ + + L + V KI
Sbjct: 75 IPGNADVSIYEIMERCALNEEDETKLKEYVESKGAIFISTPFSRAAAERLERMGVEAYKI 134
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 191
GSG+ NN L+ AS K P+I+STGM D ++ DI Q+ LLHC + YP P
Sbjct: 135 GSGECNNYPLLELVASYKKPIILSTGMNDIPSIAKAVDIFRKHGVQYALLHCTNVYPTPD 194
Query: 192 EDCNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVC 250
L + ++ F D VG S E+H T K G D C
Sbjct: 195 NLIRLGAMNQLQDAFDDAVVGLSDHSIDNLACLGAVAVGASILERHFTDHKQRTGPDINC 254
Query: 251 SLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDV 310
S+ E + L+++ + ++A G K V E ID S+V KGE ++
Sbjct: 255 SMDTEECRSLIQESKRMKAMRGGQ-KGAVAEEQVTIDFAYASVVTIKPIKKGETFSQDNL 313
Query: 311 KIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+K A E+++ KT D + D L D
Sbjct: 314 WVKRPGTGQFLADDYENLMGKTAAQDIENDVQLRSED 350
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 108 bits (260), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 8/330 (2%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY---DNPNS 75
FIIAE NH D G +K Q T + T + ++ +
Sbjct: 11 FIIAELSGNHDQDFELAKAMIHAAAEAGVDAIKLQ-TYTPDTMTLDVRHGEFMVSESDSL 69
Query: 76 W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
W G + ++ LF A+ +G++ +S D+ + FL ++ VP KI S
Sbjct: 70 WRGSNLYDLYKKASTPWEWHKPLFELAESLGLVAFSSPFDLSAVAFLESIDVPLYKIASF 129
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFED 193
+ ++ ++ A P+I+STGM + + + + I + LL C S YP ED
Sbjct: 130 EMTDIPLIQAVARTGKPIIMSTGMASEEEIAEAVATIRAIGDNPLTLLKCTSTYPSKIED 189
Query: 194 CNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLT 253
NL + D PVG S EKH LD+S G D S+
Sbjct: 190 SNLVTMADLAAKTGCPVGLSDHTQGLGAAVAATALGATVIEKHFVLDRSAGGVDAEFSME 249
Query: 254 PSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKIK 313
P E + LV R +A+LGT +E K ++S+ + G IL +KI
Sbjct: 250 PEEMKALVVACRAAKAALGTVTYGGSDAE-QAAKKYRRSIYVAVDLPAGTILTEEHLKI- 307
Query: 314 VAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
+ GL + +V+ KTL+ D ++ +PL
Sbjct: 308 IRPSFGLAPKYWPEVLGKTLMEDAQKGQPL 337
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 107 bits (258), Expect = 3e-22
Identities = 80/339 (23%), Positives = 143/339 (42%), Gaps = 12/339 (3%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
+G +P FI+AE NH G GA +K Q T + T + +
Sbjct: 15 LGPGHPAFIVAEMSGNHGGSLEYALEIVHAAKRSGADAIKLQ-TYTADTITLNSDRQDFC 73
Query: 72 NPNSWGKTYGEHKSHLEFSDTQY------RELFRYAQEVGILFTASAMDMVSFDFLVNLK 125
P+ G + +H + + Y +FR A+ + + +S D + + L L
Sbjct: 74 IPS--GTPWADHSTLWSLYNKAYTPWDWHESIFREARSLDLEIFSSPFDESAVELLEQLG 131
Query: 126 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCI 184
KI S + ++ L A P+I+STG+ ++ + + ++ + LL C
Sbjct: 132 ASAYKIASPEITHIPLLDKVARTGKPVILSTGLAALEDIELALATLRAAGSGEIILLKCT 191
Query: 185 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
+AYP P E+ NL + D + F V G S EKH T+DK+ +
Sbjct: 192 TAYPAPIEEANLRTISDMISRFGVLAGLSDHTTGAISSIVAVSMGASFIEKHFTIDKAKE 251
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
D S SEF LV+D+R+ E ++G ++ S + ++ ++SL + G++
Sbjct: 252 TVDSFFSADESEFASLVKDIRLAEKAMGEVSYEIARSALSSLNS-RRSLYVAEAIKAGDL 310
Query: 305 LYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPL 343
+ +VK V GL+ +++I + D + + L
Sbjct: 311 ITDSNVK-TVRPAFGLHPRFYKEIIGRQAKCDMQAGDRL 348
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 107 bits (257), Expect = 4e-22
Identities = 84/278 (30%), Positives = 114/278 (41%), Gaps = 19/278 (6%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
I NP F+IAE G NH+GD GA VK Q G+ + +E P
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQ-VYAGDALVSR-VESPDR 62
Query: 72 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
N H E S QY L + G+ F ASA D + + V K
Sbjct: 63 N---------RHFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQ--FCLLHCIS 185
GSGD L+ S PL++STG+ + AV+ I + SS Q LL C S
Sbjct: 113 GSGDLTAYPMLRALVSTGKPLVLSTGLSTMPEVEAAVRYIGSLDSSYITQGKLALLQCSS 172
Query: 186 AYPVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKG 245
AYP P D NL V+ + F +PVGYS E H T + K
Sbjct: 173 AYPCPDGDANLNVMHSLRQAFGLPVGYSDHTTDSEAAYAAAVMGAQILELHFTDTREGKS 232
Query: 246 -TDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSE 282
DH+ S+T E + L++ +R G+ +K+ +E
Sbjct: 233 FRDHLVSITRDELRDLLKRIRRARTLQGSWVKQPTDTE 270
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 106 bits (255), Expect = 7e-22
Identities = 88/340 (25%), Positives = 142/340 (41%), Gaps = 6/340 (1%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-TCLGEKFTKKYLERPY 70
I N+ F+IAE NH GA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 71 DNPNSWGKTYGEHKSHLE-FSDTQYRE-LFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 128
+ NS K H+ + + ++ ++ +F A+ G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 129 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFCLLHCISAY 187
KI S ++ + + LK A P+I+STG+ ++ ++ + K+ LL C S Y
Sbjct: 129 YKIASFENTDHILLKKVAQTNKPVIMSTGVSTIADIQESVKVLRDNGCKELVLLKCTSTY 188
Query: 188 PVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTD 247
P E N+ + FDVPVG S EKH TL ++ G D
Sbjct: 189 PATPESTNIYTIPHMSTLFDVPVGLSDHTMGIGVAIASVALGARIIEKHFTLSRADGGVD 248
Query: 248 HVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYP 307
SL P E + LV + SLG + +++ + + ++SL + KGE
Sbjct: 249 SSFSLEPEELKNLVVETERAFLSLG-KVNYILSEKEKKSLQFKRSLYVVKDIKKGEAFTA 307
Query: 308 GDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
+V+ + GL+ + + V+ K D K PL+ D
Sbjct: 308 LNVR-SIRPCNGLHTRYYDSVLTKQANQDIKAGTPLSLDD 346
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 106 bits (254), Expect = 1e-21
Identities = 94/336 (27%), Positives = 140/336 (41%), Gaps = 12/336 (3%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
FIIAE NH G GA +K Q T + T L ++ G
Sbjct: 13 FIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQ-TYTPDSLT---LNSDKEDFIIKGG 68
Query: 79 TYGEHKSH--LEFSDTQYR---ELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 133
+ + K + E + T Y ++F AQ GIL +S +FL KI S
Sbjct: 69 LWDKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIAS 128
Query: 134 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYPVPFE 192
++N+ F++ A +K P I+STG+ + + I +I + + L C S YP E
Sbjct: 129 FEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAIE 188
Query: 193 DCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSL 252
D NL + K F+V VG S EKH LDKS++ D SL
Sbjct: 189 DMNLKGIVSLKEKFNVEVGLSDHSFGFLAPVMAVALGARVIEKHFMLDKSIESEDSKFSL 248
Query: 253 TPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKI 312
EF+ +V VR E++LG K + ++ +SL KGE+ +VK
Sbjct: 249 DFDEFKAMVDAVRQAESALGDG-KLDLDEKVLKNRVFARSLYASKDIKKGEMFSEENVK- 306
Query: 313 KVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
V GL+ ++++ K D K + L +GDF
Sbjct: 307 SVRPSFGLHPKFYQELLGKKASKDIKFGDALKQGDF 342
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 105 bits (252), Expect = 2e-21
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 11/336 (3%)
Query: 19 FIIAEAGQN-----HQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 73
F+IAEAG N + D GA VKFQ + Y
Sbjct: 14 FVIAEAGSNWKCGDYSDDLEQAKKLIETAAKAGADAVKFQTYKPETIYVSDAGNSDYLEK 73
Query: 74 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 133
+ E HL EL +Y E I F ++ + V+ K+ S
Sbjct: 74 YGIKENINEIFEHLSMPYEMIPELKKYCDEKNIQFMSTPFSVQDAKE-VDKFTEIHKVAS 132
Query: 134 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYPVPFE 192
+ N++ L++ A + P+I+STG + ++I + + L+ C S YP P +
Sbjct: 133 FEINHIRLLEFLAKTQKPIIVSTGASTFKEIDFAINLIRKNGNDNIALMQCTSKYPCPID 192
Query: 193 DCNLTVLQDYKNTFDVPVGYSGQEXXXXXX-XXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
NL + + +PVG S EKH TLDK++ G DH +
Sbjct: 193 SLNLKTISTMGQKYKIPVGLSDHSLDPIIGPITAISLGAKFIEKHFTLDKNLPGPDHPFA 252
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVK 311
L P E + ++ +R E +LGT IK+++ E ++S+ KG++L G
Sbjct: 253 LNPDELELMITSIRNTEKALGTGIKEILPVEDELRKFAKRSIQAIQDIKKGDLLIEGQ-N 311
Query: 312 IKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
++ P N L D +Y + KK + + +GD
Sbjct: 312 FEILRPG--NRLRGMDPLYLDTISGKKSKKDVQKGD 345
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 104 bits (250), Expect = 3e-21
Identities = 87/306 (28%), Positives = 132/306 (43%), Gaps = 19/306 (6%)
Query: 16 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 75
NP IAE G +H G GA VKFQ E D P
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEILHPN--TGYVDLPTG 75
Query: 76 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 135
Y KS LE + Y+EL Y++ +LF+AS S + L LK FIKI S +
Sbjct: 76 KIPLYDRFKS-LELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 136 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ--FCLLHCISAYPVPFED 193
N + LKY A IP+I+S+G+ ++ + S++K LLHCI++YP P ++
Sbjct: 135 LNYVQLLKYCAGFNIPMILSSGVSILKDIEKAVSFLRSENKDLPLALLHCITSYPAPEKE 194
Query: 194 CNLTVLQDYKNTFDVPVGYSGQEXX-XXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSL 252
N++V+++ F + G S EKHI L + +G D +L
Sbjct: 195 YNVSVIKNLSRIFGIACGVSDHSLDPILVPALTLAAGGFIIEKHICLSRKEEGLDDPVAL 254
Query: 253 TPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVKI 312
P F+++ ++L + KK I + KL S+ + E++ G+ K+
Sbjct: 255 EPDMFKKMC-------SALNSFSKKTYDEIIEGLTKLNYSIEL-----INEVIGSGEKKL 302
Query: 313 KVAEPK 318
AE K
Sbjct: 303 SPAETK 308
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 102 bits (245), Expect = 1e-20
Identities = 87/340 (25%), Positives = 137/340 (40%), Gaps = 19/340 (5%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN---SW 76
IIAE NH GA VK Q +T + L + P+ S
Sbjct: 15 IIAELSANHNQSLEIAKDSIRAIAACGADGVKLQT------YTPECLTLQSNEPHFCISG 68
Query: 77 GKTYGEHKSHLEFSDTQ-----YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 131
G + + + + + Q ++ELF A+E+G+L +S FL +L+ P K+
Sbjct: 69 GTLWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKV 128
Query: 132 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHKQFCLLHCISAYPVP 190
S + + ++ A K P+IISTG+ +KT +I K LLHCIS YP P
Sbjct: 129 ASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLHCISEYPAP 188
Query: 191 FEDCNLTVLQDYKNT---FDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTD 247
E NL + T +++ G S EKH LD S+ G D
Sbjct: 189 LESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFILDSSLGGVD 248
Query: 248 HVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYP 307
S+ EF+ +V VR +LG K+ + +S+ + + KGE
Sbjct: 249 SAFSMNKDEFKAMVEQVRDTALALGCKKPKISADIRKKRRQFARSIWVSADIKKGEKFTH 308
Query: 308 GDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
++ + V G + +L ++ K+ K +PL D
Sbjct: 309 KNLSV-VRPSGGEHPRYLHKILGKSAKVALKAAQPLRLSD 347
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 100 bits (240), Expect = 5e-20
Identities = 72/265 (27%), Positives = 111/265 (41%), Gaps = 4/265 (1%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 79
+IAE G NH GD GA VKFQ T E ++++ D +
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQ-TLTREGLIARFVKGA-DGTVTENPK 63
Query: 80 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 139
+ + D + L A + G+ F ++ + + + + +L V KI SGD
Sbjct: 64 FAAF-GNAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGDLTFT 122
Query: 140 LFLKYAASKKIPLIISTGMVDKTAVKT-IYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 198
L+ + LI+STG V T + + S LHC ++YP +ED NL+
Sbjct: 123 PLLEALGATGKRLILSTGASYLDEVTTAVTTLTRSGCPHLTALHCAASYPPAWEDLNLSA 182
Query: 199 LQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQ 258
+ + T +PVG S EKH+T D++ G DH ++ E
Sbjct: 183 ITTLQKTLGLPVGLSDHSPGAMAPIAAAALGAVVIEKHVTFDRATPGPDHPFAMEMDELA 242
Query: 259 QLVRDVRVIEASLGTPIKKVVTSEI 283
L+ D+R +E +LG KK SEI
Sbjct: 243 ALIADLRNLEIALGDGDKKPAASEI 267
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 99 bits (238), Expect = 9e-20
Identities = 86/335 (25%), Positives = 134/335 (40%), Gaps = 9/335 (2%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 74
+NP +IIAE G H G GA VKFQ T + E T P
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQ-THIAEAETLPNAPSPSYFSA 62
Query: 75 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
Y + FS Q+R L A+ + F +S + + D L ++ V KI SG
Sbjct: 63 EPRTAYFKRTG---FSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 194
+ +N+ L A P+ +S+GM + + + LL C S YP P E
Sbjct: 120 EVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGS--ALTLLQCTSKYPCPPEQV 177
Query: 195 NLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTP 254
L + + + +PVGYS EKH T K M G+D S+ P
Sbjct: 178 GLNAMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEP 237
Query: 255 SEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKL-QKSLVMGSTKNKGEILYPGDVKIK 313
EF++L R+++ + +P+ K S + + + +KS+V + + + K
Sbjct: 238 DEFRRLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFK 297
Query: 314 VAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGDF 348
G++A +DVI + +V D DF
Sbjct: 298 -KPGDGISAAKYKDVIGRRIVRALPRDHKFAYEDF 331
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 98.7 bits (235), Expect = 2e-19
Identities = 84/336 (25%), Positives = 144/336 (42%), Gaps = 13/336 (3%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEKFTKKYLERPYDNPNSW 76
IIAE G NH GD G VKFQ + K +K Y + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 77 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 136
+ + ++ +F +++++ Y + +LF ++ D S +++ L K+ S D
Sbjct: 83 FELFSKYD---KFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANYINQLS-KIHKVASVDI 138
Query: 137 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCN 195
N + + AS +I+STG + +K +I S K LLHC+ YP +D N
Sbjct: 139 TNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDAN 198
Query: 196 LTVLQDYKNTF-DVPVGYSGQ---EXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCS 251
L ++ K +F + +GYS + EKH T DK ++G DH S
Sbjct: 199 LLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALIIEKHFTYDKKIQGNDHYHS 258
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDVK 311
+ ++ + L ++ + G K + +E I ++SL KG IL ++
Sbjct: 259 MNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSLTSKFLIKKGSIL-SKEMI 317
Query: 312 IKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEGD 347
I G+ +E+V+ + + + KED P+N D
Sbjct: 318 IPKRPGNGICPSKIEEVLGRKVKKEIKEDSPINWED 353
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 97.5 bits (232), Expect = 5e-19
Identities = 72/277 (25%), Positives = 116/277 (41%), Gaps = 9/277 (3%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK----TCLGEKFTKKYLERPY 70
+NP + IA+ G NH GA KFQ + + + K+
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 71 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 130
+ W ++ + S EL Y +E GI + + D+ +FL N V K
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTEELHSYCKECGISYMTTPYDISILEFL-NQYVACWK 125
Query: 131 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP-- 188
IGSGD L + + P+ I+TG + T V + + K+ L+ C + Y
Sbjct: 126 IGSGDITWLDLISKVSQLGKPIAIATGASNFTEVCQAVNTVLQHTKKIILMQCNTNYTGC 185
Query: 189 -VPFEDCNLTVLQDYKNTFD-VPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGT 246
F+ NL+VL YKN+F + +G S EKH T D + KG
Sbjct: 186 LSNFDYLNLSVLTTYKNSFPGITLGISDHTPGHISVLGAITLGAQVIEKHFTDDNNRKGP 245
Query: 247 DHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEI 283
DH S++PS ++ +V ++ S+G +K++ +EI
Sbjct: 246 DHSFSMSPSAWESMVEASYLLHRSIGDGVKRIEDNEI 282
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 95.1 bits (226), Expect = 2e-18
Identities = 69/245 (28%), Positives = 105/245 (42%), Gaps = 10/245 (4%)
Query: 22 AEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYG 81
AE NH G+ GA +K QK + +T++ L Y +P +G TY
Sbjct: 98 AEFTTNHMGNFNVLMRMVEQAVDAGADYIKMQKKDVENFYTEEKLNSNYKSP--YGHTYR 155
Query: 82 EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN--- 138
E++ EF T + +++ I + A+ D+ S F++ +P++K+ S +S N
Sbjct: 156 EYRKIFEFDRTDFDRFDEKCEDLDIEWFATPQDIKSLHFVLEYNMPYVKVASTNSRNDEM 215
Query: 139 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC---N 195
L L+ K L+IS G VK DH L HC+S YPVP E+ N
Sbjct: 216 LTELRDKVPKNTGLVISIGGSTMNEVKDTLSHF-PDH-NIILQHCVSEYPVPPENLGLGN 273
Query: 196 LTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPS 255
+ VL++ + V +GYSG E E+H L + SL P
Sbjct: 274 IPVLEEKFGSDRVSIGYSGHETGIGASLAAIDMGAELVERHFCLSRRSFVHHIEPSLEPD 333
Query: 256 EFQQL 260
EF +L
Sbjct: 334 EFDEL 338
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 89.8 bits (213), Expect = 9e-17
Identities = 77/296 (26%), Positives = 109/296 (36%), Gaps = 18/296 (6%)
Query: 20 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 79
IIAE G NH GD GA VK Q F L P
Sbjct: 24 IIAEVGLNHGGDADLAWEMIESAWEHGADLVKLQS------FAPGGLLHP-------SLP 70
Query: 80 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 139
Y + S Q+ LF A+ GI + D + D ++ +K+ S D +N
Sbjct: 71 YAASMEGMMLSLRQHEALFERARRQGIALITTPFDAPTLDLCTRFRIAAVKVASMDLDNT 130
Query: 140 LFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 198
L+ A +P+I+S GM D + K + + S LLHCIS YP ED L
Sbjct: 131 AHLRAVARTGLPVILSCGMGDHADIGKALATLRESGATDVTLLHCISDYPARLEDMQLAE 190
Query: 199 LQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSM----KGTDHVCSLTP 254
+ F VPVG S E+H T D ++ DH S+TP
Sbjct: 191 MPRLAARFGVPVGLSDHSLGLEASRMALALGARVIERHFTTDPALMERIPDADHDISITP 250
Query: 255 SEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEILYPGDV 310
++ ++L +LG + + E ++ L + G IL DV
Sbjct: 251 AQLRELRLAAERTALALGGAERVLAPQESAGRTASRRGLYARTRLAAGHILRAEDV 306
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 88.6 bits (210), Expect = 2e-16
Identities = 86/342 (25%), Positives = 137/342 (40%), Gaps = 13/342 (3%)
Query: 12 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 71
IG ++IAE NH G+ GAS VK Q T + T K +RP
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLKS-DRPEF 65
Query: 72 NPNSWGKTYGEHKSH--LEFSDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKV 126
+ G + H + E++ T + + LF +E+G+ +S D + D L +L
Sbjct: 66 QIH--GGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDC 123
Query: 127 PFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDI-ISSDHKQFCLLHCIS 185
P KI S + +L ++YAA PLI+STGM ++ + ++ + Q LLHC+S
Sbjct: 124 PAYKIASFELVDLPLIRYAAQTGKPLIMSTGMANEAEIAAAVEMALKHGSGQLALLHCVS 183
Query: 186 AYPVPFEDCNLTVLQDYKN-TFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMK 244
YP P + NL + + + TL ++
Sbjct: 184 GYPAPAAEYNLRTIPMLRQLLWRRGRALRSHSGVGDRHRRHSTRGDPSSRSTFTLARADG 243
Query: 245 GTDHVCSLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPCIDKLQKSLVMGSTKNKGEI 304
G D S+ P E +L+ V A+LG ++ SE ++SL + GE
Sbjct: 244 GPDCAFSMEPVELTELIASVNTAHAALGVADYQLTQSE-QGNRAFRRSLYLVKDIAAGEA 302
Query: 305 LYPGDVKIKVAEPKGLNALHLEDVIYKTLVYDKKEDEPLNEG 346
L +K V GL + +I K + D ++P G
Sbjct: 303 LTADHIK-SVRPALGLPPADYDRIIGKRVSRDMAANQPAELG 343
>UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=2; Proteobacteria|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Magnetococcus sp. (strain MC-1)
Length = 500
Score = 85.0 bits (201), Expect = 3e-15
Identities = 72/271 (26%), Positives = 108/271 (39%), Gaps = 8/271 (2%)
Query: 19 FIIAEAGQN----HQG-DXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 73
+IIAEAG N H D GA VKFQ + + + Y
Sbjct: 161 YIIAEAGSNWRMGHPARDLAMGKALIDAAVVSGADAVKFQTYRPEKVYVANAGQSNYLAE 220
Query: 74 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 133
+ + + + L + +L Y ++ GI F ++ + F ++ VP KI S
Sbjct: 221 SGIKQDIRDIFADLAMPYSMIEDLAGYCKKAGIQFLSTGFSVEDFQ-AIDPWVPLHKIAS 279
Query: 134 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPVPFE 192
+ ++L L AA+ PL++STG + + S + CLL C + YP P
Sbjct: 280 YEISHLRLLDLAANSGKPLLLSTGASRAEDIAWAVERYHSQGGRDLCLLQCTAKYPAPLA 339
Query: 193 DCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXX-XEKHITLDKSMKGTDHVCS 251
N VL + + V VG S EKH TL ++ G DH +
Sbjct: 340 TVNSAVLPWLQRRYGVSVGLSDHSRDPITAPVAAVAQGARCIEKHYTLHNALPGPDHSFA 399
Query: 252 LTPSEFQQLVRDVRVIEASLGTPIKKVVTSE 282
+T E Q+VR +R E G IK+V E
Sbjct: 400 ITADELTQMVRRIREAEEVRGDGIKQVQPQE 430
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 73.3 bits (172), Expect = 8e-12
Identities = 57/254 (22%), Positives = 104/254 (40%), Gaps = 13/254 (5%)
Query: 21 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 80
IAE G N GD GA+ KFQ +K +DN G+
Sbjct: 4 IAEIGWNFMGDMKLAEDMIAAAAQSGATTAKFQYWN-----PEKLKAGAWDND---GRRE 55
Query: 81 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 140
+K+ L Q +L + + F S + +F+ IKI S + N+
Sbjct: 56 IYNKACLNADKIQ--QLTELCSKHNVKFLLSVFNKEDAEFVSQFSTEAIKIPSHEVANIE 113
Query: 141 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISS---DHKQFCLLHCISAYPVPFEDCNLT 197
++YA S + +S G + +K + +++ S + + +HC+S+YP P E NL
Sbjct: 114 LIRYALSTYKRVFLSLGACTEEELKDVSELVGSIRSNGEDVVAMHCVSSYPCPVEKVNLP 173
Query: 198 VLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEF 257
+ + + F+ +G S EKH T++ + G D+ ++ P F
Sbjct: 174 RMAELQKLFNGELGLSDHSQSVNVPAYAVAMGATVIEKHFTVNHDLPGRDNKFAVLPEGF 233
Query: 258 QQLVRDVRVIEASL 271
+ +V + + +++L
Sbjct: 234 EAMVANCQEAKSAL 247
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 72.5 bits (170), Expect = 1e-11
Identities = 72/278 (25%), Positives = 114/278 (41%), Gaps = 29/278 (10%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 74
++P FI AE NH D G VKFQ + E F + L +
Sbjct: 4 HSPLFI-AEVSSNHHRDLQRCIEFIKTAAEIGCDAVKFQLFKIEELFAPEILSK------ 56
Query: 75 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 134
+ E + +L + E GI F+ + + D + L+ PF+
Sbjct: 57 ---SEMHRKRKEWELPVSFLPQLKQSCDEYGIQFSCTPFYL---DAVAELE-PFVDFYKI 109
Query: 135 DSNNLLF---LKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQFCLLHCISAY 187
S LL+ L P++IS GM A+KT+ + +SD LLHC+SAY
Sbjct: 110 ASYELLWDDLLAACVKTGKPVVISAGMATIEEIDHALKTLKENGASD---ITLLHCVSAY 166
Query: 188 PVPFEDCNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXX-XXXXXEKHITLDKSMKGT 246
P P +CNL VL ++N + V VG+S E H+ LD++ G
Sbjct: 167 PTPEHECNLAVLGSFRNRYQVKVGWSDHTVSSAVINRAVHRWEADVVEFHLDLDET--GD 224
Query: 247 DHVCS--LTPSEFQQLVRDVRVIEASLGTPIKKVVTSE 282
++ P + +++ V++ G+P+K+ V SE
Sbjct: 225 EYAAGHCWLPQQIATVIQGVKLATVIDGSPVKQFVASE 262
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 72.5 bits (170), Expect = 1e-11
Identities = 64/244 (26%), Positives = 97/244 (39%), Gaps = 7/244 (2%)
Query: 21 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 80
IAE G H G A+ VKFQ E L P+ Y
Sbjct: 18 IAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHP--LTGAVRLPSGAVSLY 75
Query: 81 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 140
+ LE + Y + F +A+ G+L S S + LK F+K+ S + N
Sbjct: 76 -QRFEELEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELNYPT 134
Query: 141 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ---FCLLHCISAYPVPFEDCNLT 197
+ A+ ++PLI+S+G+ ++ KQ LLHCI+AYP P + NL
Sbjct: 135 LISTLAAAELPLILSSGVCLLKEIEGALAQCRQYTKQGSSHALLHCITAYPAPETEYNLA 194
Query: 198 VLQDYKNTFDVPVGYSGQEXX-XXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSE 256
+L F++ VG S EKHI L ++ G D +L P++
Sbjct: 195 LLPALATIFNINVGVSDHSVDPLLVPLLARAHGACIVEKHICLSRTDAGLDDSIALDPAD 254
Query: 257 FQQL 260
F+ +
Sbjct: 255 FRTM 258
>UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid
synthetase NeuB; n=1; Methylophilales bacterium
HTCC2181|Rep: putative N-acetyl neuramic acid synthetase
NeuB - Methylophilales bacterium HTCC2181
Length = 615
Score = 72.1 bits (169), Expect = 2e-11
Identities = 62/247 (25%), Positives = 93/247 (37%), Gaps = 9/247 (3%)
Query: 15 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP- 73
+ P FIIAE G NH GD + +KFQ L + + +
Sbjct: 7 SKPIFIIAEIGINHGGDFSIALELIKAAAQAKVNGIKFQYRNLDNAYADGAKQIGDEMLL 66
Query: 74 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 133
K Y + L D + E GI F A D+ F ++ F K S
Sbjct: 67 KEITKNYLSPEVILRLVDDAHS----LDIEAGISFFDEA-DIADFGDGIH-HFDFFKSPS 120
Query: 134 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFED 193
+ NN + P+ +S G + + + ++ D + LHC+S YPV +
Sbjct: 121 VELNNAPLINKMLGFDKPVYVSLGCHHEDQIDDAF--MALDKNNWIALHCVSNYPVSLSN 178
Query: 194 CNLTVLQDYKNTFDVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLT 253
+L L + + P GYS + E+HIT DK+ G DH S T
Sbjct: 179 AHLGYLSHMREKWQRPYGYSSHDEDWEVCLIAMSMGATVIERHITFDKNADGLDHTTSST 238
Query: 254 PSEFQQL 260
P EF ++
Sbjct: 239 PEEFAKI 245
>UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix
orenii H 168|Rep: Antifreeze-like - Halothermothrix
orenii H 168
Length = 350
Score = 58.0 bits (134), Expect = 3e-07
Identities = 65/297 (21%), Positives = 116/297 (39%), Gaps = 22/297 (7%)
Query: 19 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 78
+II E NHQGD G VKF E YL+ N + K
Sbjct: 4 YIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPES----YLQ----NKHPLIK 55
Query: 79 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFL--VNLKVPFIKIGSGDS 136
E F++ ++ E+ Y+++ G+ A D+ S F+ + + I+I +
Sbjct: 56 KIKEWI----FTEKEWDEIINYSKQKGLDMIALCDDLDSLKFIKKYHRDLKGIEIHASSL 111
Query: 137 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FCLLHCISAYPVPFEDCN 195
N+ L+ A +I+ G ++ + + K+ L++ +YP + N
Sbjct: 112 NDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGFQSYPTDYTQIN 171
Query: 196 LTVLQDYKNTFDVPVGYS-----GQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVC 250
L +Q KN F++PVGY+ + EKH T D +K D+
Sbjct: 172 LAKMQKLKNLFNLPVGYADHTAYDDKYNVDISVMAAAMGINILEKHYTPDYGVKRIDYHA 231
Query: 251 SLTPSEFQQLVRDVRVIEASLGTPIKKVVTSEIPC--IDKLQKSLVMGSTKNKGEIL 305
++ + +Q+ + + LG + SE+ ++K++V KGE L
Sbjct: 232 AVGKKQMKQIKDKMELYLTVLGDGSLSMSDSELKYGNTGPMKKAIVARRPIKKGEKL 288
>UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus
sp. CC9311|Rep: NeuB family protein - Synechococcus sp.
(strain CC9311)
Length = 353
Score = 57.6 bits (133), Expect = 5e-07
Identities = 45/194 (23%), Positives = 75/194 (38%), Gaps = 2/194 (1%)
Query: 93 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 152
Q+RELF + G+ F S + S DF V+ IKI S + N L ++ +A +PL
Sbjct: 96 QHRELFNLIKSYGLNFIVSVYTLESVDFAVSEGAIAIKIASSNINFLPLIEKSARTGLPL 155
Query: 153 IISTGMVDKTAVKTIYDIISSDHKQFCLL--HCISAYPVPFEDCNLTVLQDYKNTFDVPV 210
+I TG + S ++ L+ H +A P P E +L+ + N
Sbjct: 156 LIDTGKSTLCEIFEARHAAYSANQDVKLIFEHSPAAPPAPIERQDLSFMNYLSNLLGEHA 215
Query: 211 GYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEAS 270
G S E + D D ++ + QLV ++ + +
Sbjct: 216 GLSHHSDDLLMIIASVAIGAKVIEFGLCRDNEADDQDVFHAVKEGQLMQLVENINRVNIA 275
Query: 271 LGTPIKKVVTSEIP 284
LG P ++ +P
Sbjct: 276 LGDPYSRIDNEVMP 289
>UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide
biosynthesis protein E; n=1; Prochlorococcus marinus
str. MIT 9312|Rep: Putative spore coat polysaccharide
biosynthesis protein E - Prochlorococcus marinus (strain
MIT 9312)
Length = 521
Score = 55.2 bits (127), Expect = 2e-06
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 2/128 (1%)
Query: 91 DTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKI 150
D Q+ ++ ++ G + D S + + KI S L+ A++
Sbjct: 88 DEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNK 147
Query: 151 PLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDV- 208
P+ ISTG + V IY + +F ++HC YP P +D NL + +K + +
Sbjct: 148 PVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTINIFKERYPLA 207
Query: 209 PVGYSGQE 216
+GYSG E
Sbjct: 208 KIGYSGHE 215
>UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=1; Pseudomonas putida F1|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Pseudomonas putida F1
Length = 369
Score = 51.2 bits (117), Expect = 4e-05
Identities = 29/127 (22%), Positives = 52/127 (40%)
Query: 80 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 139
Y + + ++ + + + + A+ D S D V +P IKI S D N+
Sbjct: 74 YVKKTEDTRLTKAEFARMVEEVRNLSCIPMATPFDEASVDLCVEFDMPIIKIASSDMNDW 133
Query: 140 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 199
++ AS + P IISTG + + I + HC+S YP ++ L +
Sbjct: 134 PLIEKIASTRRPTIISTGGASEKDLDDIVRYFEKRDIPLAINHCVSLYPSEDDELQLDQI 193
Query: 200 QDYKNTF 206
+N +
Sbjct: 194 DYLRNRY 200
>UniRef50_Q9P0B2 Cluster: HSPC269; n=2; Homo sapiens|Rep: HSPC269 -
Homo sapiens (Human)
Length = 120
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 192 EDCNLTVLQDYKNTF-DVPVGYSGQEXXXXXXXXXXXXXXXXXEKHITLDKSMKG 245
ED NL V+ +Y+ F D+P+GYSG E E+HITLDK+ KG
Sbjct: 3 EDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKG 57
>UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis
protein E; n=5; Legionella pneumophila|Rep: Spore coat
polysaccharide biosynthesis protein E - Legionella
pneumophila (strain Corby)
Length = 368
Score = 46.8 bits (106), Expect = 8e-04
Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 94 YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLI 153
Y LF + + F S ++ + DF + +K S + ++ +++ A +PLI
Sbjct: 107 YSMLFSLLKNANLPFIVSIYELDTIDFAIKQGACALKTSSSNIVHIPLIRHLAKTGLPLI 166
Query: 154 ISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGY 212
I TG T + K + S+ ++ + H +P E NL +L+ F +PVG
Sbjct: 167 IDTGRSSLTDICKAVETAKSAGCEKIIIEHSPDGHPALPEAHNLRMLRTLNQCFSLPVGL 226
Query: 213 S 213
S
Sbjct: 227 S 227
>UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide
biosynthesis protein E; n=1; Chromobacterium
violaceum|Rep: Probable spore coat polysaccharide
biosynthesis protein E - Chromobacterium violaceum
Length = 495
Score = 42.3 bits (95), Expect = 0.018
Identities = 37/183 (20%), Positives = 69/183 (37%), Gaps = 4/183 (2%)
Query: 93 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 152
Q ++L + G + D S D + + IKI S + L+ A P+
Sbjct: 77 QMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPV 136
Query: 153 IISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTF-DVPVG 211
+ ST + + + + K ++HC++ YP P + +L ++ + + V +G
Sbjct: 137 VASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTPDDHLHLARIKTLRQQYAGVRIG 196
Query: 212 YSGQE--XXXXXXXXXXXXXXXXXEKHITLDKSMKGTDHVCSLTPSEFQQLVRDVRVIEA 269
YS E EKH+ L G ++ S P + ++ + A
Sbjct: 197 YSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNY-SANPEQVRRWLAAAARALA 255
Query: 270 SLG 272
LG
Sbjct: 256 MLG 258
>UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 100
Score = 37.5 bits (83), Expect = 0.52
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 113 MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASK 148
MD ++ +FL + VPF K+ S D+NN+ +L+ A K
Sbjct: 1 MDEMAVEFLHEINVPFFKVASADTNNIPYLEKTAKK 36
>UniRef50_Q55G26 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 830
Score = 34.7 bits (76), Expect = 3.6
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 4/111 (3%)
Query: 93 QYRELFRYAQEVGILFTASAMDMVSF-DFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIP 151
+Y +LF+ Q I + S +D F ++L N++ ++IG G+ NN +F + +I
Sbjct: 188 KYMKLFKIHQFKMIFSSISKLDAYPFKEYLYNVQ---LEIGGGERNNEVFNYQHETMEIN 244
Query: 152 LIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQDY 202
+ + D +V I D+ +C S+ P + N DY
Sbjct: 245 DYLENNLPDSISVLNIIDLNKEFSNGYCRYIRPSSIPCSVKVLNFIKQSDY 295
>UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein;
n=1; Fusobacterium nucleatum subsp. nucleatum|Rep:
Tetratricopeptide repeat family protein - Fusobacterium
nucleatum subsp. nucleatum
Length = 628
Score = 34.3 bits (75), Expect = 4.8
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 102 QEVGILFTASA-MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVD 160
+E+GI +T S D+++ + NL FIK+ SG+ Y K M+D
Sbjct: 548 EEIGIFYTPSGKQDIINNKY--NLPEDFIKLKSGEIKTFFIDWYNNKTKEKFYELFNMID 605
Query: 161 KTAVKTIYDIISSDHK 176
KT++K ++++ K
Sbjct: 606 KTSIKVYLKYLNTEKK 621
>UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;
Candida albicans|Rep: Sterol 3-beta-glucosyltransferase
- Candida albicans (Yeast)
Length = 1513
Score = 33.9 bits (74), Expect = 6.3
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 52 FQKTCLG--EKFTKKYLERPYDNPNSWGKTYGE--HKSHLEFSDTQYRELFRYAQEVGIL 107
FQK L E+ K RP P WG + +K+ +E+SD++ RE+ +Y + I
Sbjct: 912 FQKVVLSVLERLHSKEGFRP--EPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIK 969
Query: 108 FTASAMDM 115
F ++M
Sbjct: 970 FAEKKIEM 977
>UniRef50_Q7VQK1 Cluster: Survival protein SurA; n=1; Candidatus
Blochmannia floridanus|Rep: Survival protein SurA -
Blochmannia floridanus
Length = 426
Score = 33.5 bits (73), Expect = 8.4
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 135 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 194
D N L + S++I IST +++TA K + + HKQF +H I P+P E
Sbjct: 136 DILNKLICNHIISQRIK--ISTHEINQTAQKLSF---INFHKQFKFIHTIIELPIPAETT 190
Query: 195 NLTVLQDY 202
+ +L ++
Sbjct: 191 QINILNNF 198
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.137 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 359,789,753
Number of Sequences: 1657284
Number of extensions: 13584969
Number of successful extensions: 27054
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 26784
Number of HSP's gapped (non-prelim): 111
length of query: 349
length of database: 575,637,011
effective HSP length: 101
effective length of query: 248
effective length of database: 408,251,327
effective search space: 101246329096
effective search space used: 101246329096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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