Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002650-TA|BGIBMGA002650-PA|IPR000891|Pyruvate
carboxyltransferase
(147 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC024194-1|AAH24194.2| 340|Homo sapiens 3-hydroxymethyl-3-methy... 171 6e-43
AL590406-2|CAI40662.1| 241|Homo sapiens protein ( Human DNA seq... 171 6e-43
AF131827-1|AAD20054.1| 191|Homo sapiens Unknown protein. 171 6e-43
U49719-1|AAB19099.1| 305|Homo sapiens hydroxymethylglutaryl-CoA... 161 1e-39
L07033-1|AAA92733.1| 325|Homo sapiens hydroxymethylglutaryl-CoA... 161 1e-39
CR456884-1|CAG33165.1| 325|Homo sapiens HMGCL protein. 161 1e-39
BT009792-1|AAP88794.1| 325|Homo sapiens 3-hydroxymethyl-3-methy... 161 1e-39
BC010570-1|AAH10570.1| 325|Homo sapiens 3-hydroxymethyl-3-methy... 161 1e-39
AL031295-19|CAI23161.1| 300|Homo sapiens 3-hydroxymethyl-3-meth... 161 1e-39
AK127587-1|BAC87045.1| 297|Homo sapiens protein ( Homo sapiens ... 63 4e-10
AL358532-3|CAH71058.1| 361|Homo sapiens lipase-like, ab-hydrola... 31 1.5
U30891-1|AAA82937.1| 1178|Homo sapiens pyruvate carboxylase prec... 30 3.6
U04641-1|AAA99537.1| 1178|Homo sapiens pyruvate: carbon-dioxide ... 30 3.6
BC011617-1|AAH11617.1| 1178|Homo sapiens pyruvate carboxylase pr... 30 3.6
>BC024194-1|AAH24194.2| 340|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1
protein.
Length = 340
Score = 171 bits (417), Expect = 6e-43
Identities = 76/124 (61%), Positives = 97/124 (78%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI
Sbjct: 210 MGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGIN 269
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDS++SGLGGCPYA+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T
Sbjct: 270 VVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTT 329
Query: 121 ESKV 124
SKV
Sbjct: 330 NSKV 333
>AL590406-2|CAI40662.1| 241|Homo sapiens protein ( Human DNA
sequence from clone RP11-418P12 on chromosome 6. ).
Length = 241
Score = 171 bits (417), Expect = 6e-43
Identities = 76/124 (61%), Positives = 97/124 (78%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI
Sbjct: 111 MGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGIN 170
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDS++SGLGGCPYA+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T
Sbjct: 171 VVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTT 230
Query: 121 ESKV 124
SKV
Sbjct: 231 NSKV 234
>AF131827-1|AAD20054.1| 191|Homo sapiens Unknown protein.
Length = 191
Score = 171 bits (417), Expect = 6e-43
Identities = 76/124 (61%), Positives = 97/124 (78%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI
Sbjct: 61 MGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGIN 120
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDS++SGLGGCPYA+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T
Sbjct: 121 VVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTT 180
Query: 121 ESKV 124
SKV
Sbjct: 181 NSKV 184
>U49719-1|AAB19099.1| 305|Homo sapiens hydroxymethylglutaryl-CoA
lyase protein.
Length = 305
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 175 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVS 234
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 235 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 294
Query: 121 ESKV 124
SKV
Sbjct: 295 SSKV 298
>L07033-1|AAA92733.1| 325|Homo sapiens hydroxymethylglutaryl-CoA
lyase protein.
Length = 325
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 195 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALTNTLMALQMGVS 254
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 255 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 314
Query: 121 ESKV 124
SKV
Sbjct: 315 SSKV 318
>CR456884-1|CAG33165.1| 325|Homo sapiens HMGCL protein.
Length = 325
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 195 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVS 254
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 255 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 314
Query: 121 ESKV 124
SKV
Sbjct: 315 SSKV 318
>BT009792-1|AAP88794.1| 325|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
(hydroxymethylglutaricaciduri protein.
Length = 325
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 195 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVS 254
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 255 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 314
Query: 121 ESKV 124
SKV
Sbjct: 315 SSKV 318
>BC010570-1|AAH10570.1| 325|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
(hydroxymethylglutaricaciduri protein.
Length = 325
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 195 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVS 254
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 255 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 314
Query: 121 ESKV 124
SKV
Sbjct: 315 SSKV 318
>AL031295-19|CAI23161.1| 300|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyaseclass T
protein.
Length = 300
Score = 161 bits (390), Expect = 1e-39
Identities = 73/124 (58%), Positives = 93/124 (75%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIK 60
MGCYE+SLGDTIGVGT G ++ +L ++ LA+H HDTYGQ L+N L L+ G+
Sbjct: 170 MGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVS 229
Query: 61 TVDSSISGLGGCPYARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPT 120
VDSS++GLGGCPYA+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T
Sbjct: 230 VVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKT 289
Query: 121 ESKV 124
SKV
Sbjct: 290 SSKV 293
>AK127587-1|BAC87045.1| 297|Homo sapiens protein ( Homo sapiens
cDNA FLJ45682 fis, clone FCBBF3001018, moderately
similar to Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4).
).
Length = 297
Score = 62.9 bits (146), Expect = 4e-10
Identities = 26/43 (60%), Positives = 33/43 (76%)
Query: 1 MGCYEVSLGDTIGVGTAGSVRRLLHEILTVAKPEQLALHFHDT 43
MGCYE+SLGDTIGVGT GS++R+L ++ P LA+H HDT
Sbjct: 240 MGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDT 282
>AL358532-3|CAH71058.1| 361|Homo sapiens lipase-like,
ab-hydrolase domain containing 2 protein.
Length = 361
Score = 31.1 bits (67), Expect = 1.5
Identities = 14/39 (35%), Positives = 20/39 (51%)
Query: 56 EFGIKTVDSSISGLGGCPYARGASGNLATEDLVYFLYGL 94
E+ + T D I G+ P+ RG G A + VY +GL
Sbjct: 10 EYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGL 48
>U30891-1|AAA82937.1| 1178|Homo sapiens pyruvate carboxylase
precursor protein.
Length = 1178
Score = 29.9 bits (64), Expect = 3.6
Identities = 13/36 (36%), Positives = 20/36 (55%)
Query: 36 LALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGG 71
L +H HDT G G++ +LA + G VD + + G
Sbjct: 768 LHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSG 803
>U04641-1|AAA99537.1| 1178|Homo sapiens pyruvate: carbon-dioxide
ligase (ADP-forming) protein.
Length = 1178
Score = 29.9 bits (64), Expect = 3.6
Identities = 13/36 (36%), Positives = 20/36 (55%)
Query: 36 LALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGG 71
L +H HDT G G++ +LA + G VD + + G
Sbjct: 768 LHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSG 803
>BC011617-1|AAH11617.1| 1178|Homo sapiens pyruvate carboxylase
protein.
Length = 1178
Score = 29.9 bits (64), Expect = 3.6
Identities = 13/36 (36%), Positives = 20/36 (55%)
Query: 36 LALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGG 71
L +H HDT G G++ +LA + G VD + + G
Sbjct: 768 LHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSG 803
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.139 0.408
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 20,005,901
Number of Sequences: 224733
Number of extensions: 753435
Number of successful extensions: 1212
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1198
Number of HSP's gapped (non-prelim): 14
length of query: 147
length of database: 73,234,838
effective HSP length: 83
effective length of query: 64
effective length of database: 54,581,999
effective search space: 3493247936
effective search space used: 3493247936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 61 (28.7 bits)
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